probability spectrum expect ions peptide protein num_prots calc_neutral_pep_mass xpress index start_scan assumed_charge precursor_neutral_mass MZratio protein_descr pI retention_time_sec compensation_voltage precursor_intensity collision_energy inverse_reduced_ion_mobility xlink_type ppm experiment_label xcorr deltacn deltacnstar spscore sprank num_tol_term num_missed_cleavages massdiff pep_length num_saavs_min num_saavs_max peff_mods light_area heavy_area light_intensity heavy_intensity intensity_ratio fval 0.975 221125_WJC_METTL3_EV_vs_WT_F01.02629.02629.2 0.0643 14-Apr R.DQINSDHR.T sp|Q12874|SF3A3_HUMAN 1 983.4421 999 24 2629 2 983.439232 492.7283 Splicing factor 3A subunit 3 OS=Homo sapiens OX=9606 GN=SF3A3 PE=1 SV=1 5.21 1242.3 - 46584 - - - -2.8868 - 0.992 0.262 - 98 1 2 0 -0.0028 8 0 0 0 1.38E+06 0.00E+00 - - - 0.951 0.9977 221125_WJC_METTL3_EV_vs_WT_F01.03142.03142.2 0.00654 16-Jun R.AAVAGEDGR.M "sp|P0DMR1|HNRC4_HUMAN,sp|P07910|HNRPC_HUMAN,sp|O60812|HNRC1_HUMAN,sp|B2RXH8|HNRC2_HUMAN,sp|B7ZW38|HNRC3_HUMAN,tr|G3V251|G3V251_HUMAN,tr|B4DY08|B4DY08_HUMAN,tr|G3V575|G3V575_HUMAN,tr|B4DSU6|B4DSU6_HUMAN,tr|G3V3K6|G3V3K6_HUMAN,tr|B2R5W2|B2R5W2_HUMAN,tr|G3V4C1|G3V4C1_HUMAN,tr|A0A0G2JPF8|A0A0G2JPF8_HUMAN,tr|A0A0G2JNQ3|A0A0G2JNQ3_HUMAN,tr|G3V576|G3V576_HUMAN,tr|G3V5X6|G3V5X6_HUMAN,tr|G3V4W0|G3V4W0_HUMAN,tr|G3V555|G3V555_HUMAN,tr|G3V2Q1|G3V2Q1_HUMAN" 19 844.4039 1.31 49 3142 2 844.401149 423.2092 Heterogeneous nuclear ribonucleoprotein C-like 4 OS=Homo sapiens OX=9606 GN=HNRNPCL4 PE=3 SV=1 4.37 1335.9 - 74705.3 - - - -3.252 - 1.459 0.412 - 140.9 1 2 0 -0.0027 9 0 0 0 3.19E+06 2.44E+06 - - - 3.176 0.9418 221125_WJC_METTL3_EV_vs_WT_F01.03151.03151.2 12.1 16-Jul R.AAVAGEDGR[166.11].M "sp|P0DMR1|HNRC4_HUMAN,sp|P07910|HNRPC_HUMAN,sp|O60812|HNRC1_HUMAN,sp|B2RXH8|HNRC2_HUMAN,sp|B7ZW38|HNRC3_HUMAN,tr|G3V251|G3V251_HUMAN,tr|B4DY08|B4DY08_HUMAN,tr|G3V575|G3V575_HUMAN,tr|B4DSU6|B4DSU6_HUMAN,tr|G3V3K6|G3V3K6_HUMAN,tr|B2R5W2|B2R5W2_HUMAN,tr|G3V4C1|G3V4C1_HUMAN,tr|A0A0G2JPF8|A0A0G2JPF8_HUMAN,tr|A0A0G2JNQ3|A0A0G2JNQ3_HUMAN,tr|G3V576|G3V576_HUMAN,tr|G3V5X6|G3V5X6_HUMAN,tr|G3V4W0|G3V4W0_HUMAN,tr|G3V555|G3V555_HUMAN,tr|G3V2Q1|G3V2Q1_HUMAN" 19 854.4122 1.31 52 3151 2 854.410173 428.2134 Heterogeneous nuclear ribonucleoprotein C-like 4 OS=Homo sapiens OX=9606 GN=HNRNPCL4 PE=3 SV=1 4.37 1337.3 - 71582.8 - - - -2.3314 - 1.041 0.127 - 198.7 1 2 0 -0.002 9 0 0 0 3.19E+06 2.44E+06 - - - 0.0946 0.9917 221125_WJC_METTL3_EV_vs_WT_F01.03156.03156.2 0.018 12-Jun R.MVQEAEK[136.11].Y "sp|P0DMV8|HS71A_HUMAN,sp|P11142|HSP7C_HUMAN,sp|P0DMV9|HS71B_HUMAN,tr|E9PNE6|E9PNE6_HUMAN,tr|A8K7Q2|A8K7Q2_HUMAN,tr|E9PKE3|E9PKE3_HUMAN,tr|E9PM13|E9PM13_HUMAN,tr|E9PS65|E9PS65_HUMAN,tr|V9GZ37|V9GZ37_HUMAN,tr|A0A0G2JIW1|A0A0G2JIW1_HUMAN" 10 841.4095 0.13 53 3156 2 841.405586 421.712 Heat shock 70 kDa protein 1A OS=Homo sapiens OX=9606 GN=HSPA1A PE=1 SV=1 4.53 1338 - 138423 - - - -4.6565 - 1.396 0.381 - 144.6 1 2 0 -0.0039 7 0 0 0 1.88E+06 1.43E+07 - - - 2.9109 0.7821 221125_WJC_METTL3_EV_vs_WT_F01.03500.03500.2 2.85 14-Apr R.ASAQSSVR.S "sp|Q15057|ACAP2_HUMAN,tr|A0A087X1H5|A0A087X1H5_HUMAN" 2 804.409 219.19 73 3500 2 804.406456 403.2118 "Arf-GAP with coiled-coil, ANK repeat and PH domain-containing protein 2 OS=Homo sapiens OX=9606 GN=ACAP2 PE=1 SV=3" 9.79 1400.1 - 2.11E+06 - - - -3.1377 - 0.85 0.15 - 27.4 2 2 0 -0.0025 8 0 0 0 3.98E+07 1.81E+05 - - - -0.4765 0.9426 221125_WJC_METTL3_EV_vs_WT_F01.03716.03716.2 4.54 14-May K.IQNDAGVR.L "sp|Q96I24|FUBP3_HUMAN,sp|Q92945|FUBP2_HUMAN,sp|Q96AE4|FUBP1_HUMAN,tr|M0R0I5|M0R0I5_HUMAN,tr|E9PEB5|E9PEB5_HUMAN,tr|M0R0C6|M0R0C6_HUMAN,tr|A0A087WTP3|A0A087WTP3_HUMAN" 7 871.4512 1.84 79 3716 2 871.448585 436.7329 Far upstream element-binding protein 3 OS=Homo sapiens OX=9606 GN=FUBP3 PE=1 SV=2 5.84 1439.6 - 116046 - - - -2.9766 - 1.127 0.155 - 73.1 2 2 0 -0.0026 8 0 0 0 3.24E+06 1.76E+06 - - - 0.4111 0.881 221125_WJC_METTL3_EV_vs_WT_F01.03839.03839.2 0.307 12-Jun R.NSTIPTK[136.11].Q "sp|P0DMV8|HS71A_HUMAN,sp|P34931|HS71L_HUMAN,sp|P0DMV9|HS71B_HUMAN,tr|Q53FA3|Q53FA3_HUMAN,tr|V9GZ37|V9GZ37_HUMAN,tr|A0A0G2JIW1|A0A0G2JIW1_HUMAN" 6 767.4269 0.28 84 3839 2 767.423552 384.7207 Heat shock 70 kDa protein 1A OS=Homo sapiens OX=9606 GN=HSPA1A PE=1 SV=1 8.75 1462.5 - 433886 - - - -4.3222 - 1.059 0.178 - 157.9 1 2 0 -0.0033 7 0 0 0 6.14E+06 2.21E+07 - - - 0.5363 0.9568 221125_WJC_METTL3_EV_vs_WT_F01.03925.03925.2 0.921 12-May R.FTDEESR.V "sp|Q9NYF8|BCLF1_HUMAN,tr|H0YF00|H0YF00_HUMAN,tr|E9PKI6|E9PKI6_HUMAN,tr|A0A1W2PQ43|A0A1W2PQ43_HUMAN,tr|E9PK91|E9PK91_HUMAN,tr|E9PK09|E9PK09_HUMAN,tr|E9PQN2|E9PQN2_HUMAN" 7 882.3719 2.48 89 3925 2 882.369035 442.1932 Bcl-2-associated transcription factor 1 OS=Homo sapiens OX=9606 GN=BCLAF1 PE=1 SV=2 4.14 1477.8 - 193183 - - - -3.2764 - 0.923 0.267 - 86.7 1 2 0 -0.0029 7 0 0 0 1.75E+07 7.05E+06 - - - 0.7583 0.9814 221125_WJC_METTL3_EV_vs_WT_F01.03939.03939.2 0.0766 18-Oct R.IAGQVAAANK.K "sp|P39019|RS19_HUMAN,tr|A0A075B6E2|A0A075B6E2_HUMAN" 2 941.5294 1.29 90 3939 2 941.524712 471.772 40S ribosomal protein S19 OS=Homo sapiens OX=9606 GN=RPS19 PE=1 SV=2 8.75 1480.1 - 654247 - - - -5.011 - 1.597 0.277 - 130.9 1 2 0 -0.0047 10 0 0 0 1.28E+07 9.93E+06 - - - 2.3921 0.7993 221125_WJC_METTL3_EV_vs_WT_F01.03956.03956.2 1.5 12-May R.FTDEESR[166.11].V "sp|Q9NYF8|BCLF1_HUMAN,tr|H0YF00|H0YF00_HUMAN,tr|E9PKI6|E9PKI6_HUMAN,tr|A0A1W2PQ43|A0A1W2PQ43_HUMAN,tr|E9PK91|E9PK91_HUMAN,tr|E9PK09|E9PK09_HUMAN,tr|E9PQN2|E9PQN2_HUMAN" 7 892.3802 2.48 91 3956 2 892.374813 447.1974 Bcl-2-associated transcription factor 1 OS=Homo sapiens OX=9606 GN=BCLAF1 PE=1 SV=2 4.14 1483.1 - 188743 - - - -6.0322 - 1.146 0.199 - 95.1 1 2 0 -0.0054 7 0 0 0 1.75E+07 7.05E+06 - - - 0.9409 0.9795 221125_WJC_METTL3_EV_vs_WT_F01.03988.03988.2 0.688 12-Sep R.K[136.11]GVITVK[136.11].D "sp|P10809|CH60_HUMAN,tr|A0A7I2V599|A0A7I2V599_HUMAN,tr|E7EXB4|E7EXB4_HUMAN,tr|A0A7I2YQ71|A0A7I2YQ71_HUMAN,tr|A0A7I2V5M1|A0A7I2V5M1_HUMAN,tr|A0A7I2V5K3|A0A7I2V5K3_HUMAN,tr|A0A7I2V369|A0A7I2V369_HUMAN" 7 759.5189 0.001 94 3988 2 759.516857 380.7667 "60 kDa heat shock protein, mitochondrial OS=Homo sapiens OX=9606 GN=HSPD1 PE=1 SV=2" 10 1488.7 - 251025 - - - -2.7228 - 1.537 0.082 - 298.3 1 2 0 -0.0021 7 0 0 0 0.00E+00 6.09E+06 - - - 1.008 0.9982 221125_WJC_METTL3_EV_vs_WT_F01.03996.03996.2 0.0219 14-Aug R.NTEEEGLK.Y "sp|Q9NYF8|BCLF1_HUMAN,tr|E9PKI6|E9PKI6_HUMAN,tr|A0A1W2PQ43|A0A1W2PQ43_HUMAN,tr|E9PK91|E9PK91_HUMAN,tr|E9PK09|E9PK09_HUMAN,tr|E9PQN2|E9PQN2_HUMAN" 6 918.4294 1.65 95 3996 2 918.427756 460.222 Bcl-2-associated transcription factor 1 OS=Homo sapiens OX=9606 GN=BCLAF1 PE=1 SV=2 4.25 1490.1 - 724242 - - - -1.8347 - 1.532 0.282 - 138.3 1 2 0 -0.0017 8 0 0 0 2.11E+07 1.28E+07 - - - 2.4099 0.9783 221125_WJC_METTL3_EV_vs_WT_F01.04024.04024.2 0.242 12-May R.EAQVNVR.M "sp|Q9Y2W1|TR150_HUMAN,tr|A0A3B3ITZ9|A0A3B3ITZ9_HUMAN" 2 814.4297 1.56 99 4024 2 814.426886 408.2221 Thyroid hormone receptor-associated protein 3 OS=Homo sapiens OX=9606 GN=THRAP3 PE=1 SV=2 6.1 1494.6 - 212297 - - - -3.4748 - 1.227 0.227 - 209.1 1 2 0 -0.0028 7 0 0 0 1.51E+07 9.64E+06 - - - 1.3649 0.8094 221125_WJC_METTL3_EV_vs_WT_F01.04051.04051.2 9.23 16-May R.TAQDLSSPR.T "sp|Q9UHI6|DDX20_HUMAN,tr|A0A7P0TBA6|A0A7P0TBA6_HUMAN,tr|A0A7P0Z4I9|A0A7P0Z4I9_HUMAN,tr|A0A7P0T8G7|A0A7P0T8G7_HUMAN,tr|A0A7P0TB94|A0A7P0TB94_HUMAN,tr|A0A7P0T9T8|A0A7P0T9T8_HUMAN,tr|A0A7P0Z4K8|A0A7P0Z4K8_HUMAN" 7 973.4829 114.48 104 4051 2 973.480446 487.7487 Probable ATP-dependent RNA helicase DDX20 OS=Homo sapiens OX=9606 GN=DDX20 PE=1 SV=2 5.5 1499 - 159990 - - - -2.4931 - 1.038 0.054 - 109 3 2 0 -0.0024 9 0 0 0 2.89E+06 2.52E+04 - - - -0.6662 0.8795 221125_WJC_METTL3_EV_vs_WT_F01.04239.04239.2 2.91 14-Apr R.GFSANSAR.L "sp|P48668|K2C6C_HUMAN,sp|P04259|K2C6B_HUMAN,sp|P02538|K2C6A_HUMAN" 3 808.3828 0.12 119 4239 2 808.383657 405.1987 "Keratin, type II cytoskeletal 6C OS=Homo sapiens OX=9606 GN=KRT6C PE=1 SV=3" 9.75 1531.3 - 215549 - - - 1.1034 - 0.886 0.119 - 46.5 7 2 0 0.0009 8 0 0 0 3.16E+06 2.74E+07 - - - -0.8229 0.7764 221125_WJC_METTL3_EV_vs_WT_F01.04278.04278.2 3.74 14-Apr K.SVLADQGK.S "sp|Q9NYF8|BCLF1_HUMAN,tr|E9PKI6|E9PKI6_HUMAN,tr|A0A1W2PQ43|A0A1W2PQ43_HUMAN,tr|E9PK91|E9PK91_HUMAN,tr|E9PK09|E9PK09_HUMAN,tr|E9PQN2|E9PQN2_HUMAN" 6 816.4341 0.95 122 4278 2 816.431599 409.2243 Bcl-2-associated transcription factor 1 OS=Homo sapiens OX=9606 GN=BCLAF1 PE=1 SV=2 5.55 1538 - 152159 - - - -3.1025 - 1.004 0.101 - 45.2 5 2 0 -0.0025 8 0 0 0 2.24E+07 2.35E+07 - - - -0.514 0.7637 221125_WJC_METTL3_EV_vs_WT_F01.04442.04442.2 1.9 14-Jun R.TSIEVGVK.G sp|Q03052|PO3F1_HUMAN 1 831.4702 999 126 4442 2 831.467233 416.7424 "POU domain, class 3, transcription factor 1 OS=Homo sapiens OX=9606 GN=POU3F1 PE=2 SV=3" 5.66 1566.7 - 2.08E+06 - - - -3.5479 - 1.196 0.027 - 118.8 2 2 0 -0.0029 8 0 0 0 1.80E+09 0.00E+00 - - - -0.3552 0.9509 221125_WJC_METTL3_EV_vs_WT_F01.04521.04521.2 5.04 16-Jun K.EGVVAAAEK.T "sp|Q16143|SYUB_HUMAN,sp|P37840|SYUA_HUMAN,tr|A0A669KB41|A0A669KB41_HUMAN,tr|G4Y816|G4Y816_HUMAN,tr|D6RA31|D6RA31_HUMAN,tr|A0A669KBH5|A0A669KBH5_HUMAN,tr|H6UYS7|H6UYS7_HUMAN,tr|E7EPV7|E7EPV7_HUMAN" 8 872.4603 1.79 131 4521 2 872.46103 437.2374 Beta-synuclein OS=Homo sapiens OX=9606 GN=SNCB PE=1 SV=1 4.53 1580.5 - 130288 - - - 0.7828 - 0.928 0.146 - 60.7 3 2 0 0.0007 9 0 0 0 3.53E+06 1.97E+06 - - - -0.3102 0.9997 221125_WJC_METTL3_EV_vs_WT_F01.04713.04713.2 0.000187 24-May R.FSSSSGYGGGSSR.V sp|P35527|K1C9_HUMAN 1 1234.5214 999 139 4713 2 1234.519611 618.268 "Keratin, type I cytoskeletal 9 OS=Homo sapiens OX=9606 GN=KRT9 PE=1 SV=3" 8.75 1615.6 - 39894.4 - - - -1.4848 - 1.091 0.632 - 77.5 1 2 0 -0.0018 13 0 0 0 2.28E+06 0.00E+00 - - - 3.9319 0.9893 221125_WJC_METTL3_EV_vs_WT_F01.04848.04848.2 0.316 26-Apr K.K[136.11]GPGEVAGTVTGQK[136.11].R "sp|Q86U44|MTA70_HUMAN,tr|F5H6D8|F5H6D8_HUMAN,tr|H0YFV6|H0YFV6_HUMAN,tr|B4DTN4|B4DTN4_HUMAN" 4 1343.738 0.001 142 4848 2 1343.737007 672.8763 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 8.59 1639.6 - 0 - - - -0.7234 - 0.964 0.227 - 31.9 1 2 0 -0.001 14 0 0 0 0.00E+00 4.36E+06 - - - 0.6253 0.9986 221125_WJC_METTL3_EV_vs_WT_F01.04897.04897.3 0.00157 Sep-52 K.K[136.11]GPGEVAGTVTGQK[136.11].R "sp|Q86U44|MTA70_HUMAN,tr|F5H6D8|F5H6D8_HUMAN,tr|H0YFV6|H0YFV6_HUMAN,tr|B4DTN4|B4DTN4_HUMAN" 4 1343.738 0 144 4897 3 1343.734883 448.9199 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 8.59 1648.2 - 284603 - - - -2.304 - 1.673 0.338 - 95.7 1 2 0 -0.0031 14 0 0 0 1.02E+05 3.23E+07 - - - 3.6751 0.9926 221125_WJC_METTL3_EV_vs_WT_F01.04908.04908.2 0.0815 12-Jun K.SDSFAPK[136.11].T "sp|Q9Y2W1|TR150_HUMAN,tr|A0A3B3ITZ9|A0A3B3ITZ9_HUMAN" 2 758.369 0.001 146 4908 2 758.368518 380.1918 Thyroid hormone receptor-associated protein 3 OS=Homo sapiens OX=9606 GN=THRAP3 PE=1 SV=2 5.55 1650 - 72340.9 - - - -0.6606 - 1.072 0.218 - 195.5 1 2 0 -0.0005 7 0 0 0 0.00E+00 3.66E+06 - - - 0.8713 0.8618 221125_WJC_METTL3_EV_vs_WT_F01.05012.05012.2 2.78 16-Apr R.SQESGYYDR.M "sp|P43243|MATR3_HUMAN,tr|A8MXP9|A8MXP9_HUMAN,tr|D6R991|D6R991_HUMAN,tr|A0A0R4J2E8|A0A0R4J2E8_HUMAN,tr|D6REM6|D6REM6_HUMAN" 5 1103.452 1.45 151 5012 2 1103.449574 552.7333 Matrin-3 OS=Homo sapiens OX=9606 GN=MATR3 PE=1 SV=2 4.37 1669.6 - 121565 - - - -2.1686 - 0.738 0.171 - 43.4 1 2 0 -0.0024 9 0 0 0 1.59E+06 1.10E+06 - - - -0.5757 0.9985 221125_WJC_METTL3_EV_vs_WT_F01.05213.05213.2 0.208 22-Jul K.VGGTSDVEVNEK.K "sp|P10809|CH60_HUMAN,tr|A0A7I2V2X6|A0A7I2V2X6_HUMAN,tr|A0A7I2YQK6|A0A7I2YQK6_HUMAN,tr|A0A7I2V599|A0A7I2V599_HUMAN" 4 1232.5885 3.3 161 5213 2 1232.586306 617.3015 "60 kDa heat shock protein, mitochondrial OS=Homo sapiens OX=9606 GN=HSPD1 PE=1 SV=2" 4.14 1705.4 - 85491.2 - - - -1.7484 - 1.658 0.296 - 172.5 1 2 0 -0.0022 12 0 0 0 7.85E+06 2.38E+06 - - - 2.5569 0.9369 221125_WJC_METTL3_EV_vs_WT_F01.05250.05250.2 7.27 12-May K.NADELVK[136.11].Q "sp|P17987|TCPA_HUMAN,tr|F5H726|F5H726_HUMAN,tr|F5H136|F5H136_HUMAN,tr|E7ERF2|E7ERF2_HUMAN,tr|F5H676|F5H676_HUMAN" 5 795.4218 0.46 166 5250 2 795.421139 398.7182 T-complex protein 1 subunit alpha OS=Homo sapiens OX=9606 GN=TCP1 PE=1 SV=1 4.37 1711.7 - 301703 - - - -0.8096 - 1.053 0.037 - 65.1 1 2 0 -0.0006 7 0 0 0 5.30E+06 1.14E+07 - - - -0.5223 0.8439 221125_WJC_METTL3_EV_vs_WT_F01.05265.05265.2 6.75 14-May R.TQNVLGEK[136.11].G "sp|P23396|RS3_HUMAN,tr|E9PL09|E9PL09_HUMAN,tr|E9PK82|E9PK82_HUMAN,tr|F2Z2S8|F2Z2S8_HUMAN,tr|H0YCJ7|H0YCJ7_HUMAN,tr|E9PQ96|E9PQ96_HUMAN,tr|E9PJH4|E9PJH4_HUMAN,tr|E9PPU1|E9PPU1_HUMAN,tr|H0YF32|H0YF32_HUMAN" 9 895.4854 0.82 167 5265 2 895.484546 448.75 40S ribosomal protein S3 OS=Homo sapiens OX=9606 GN=RPS3 PE=1 SV=2 5.66 1714.5 - 92121.7 - - - -1.005 - 0.77 0.088 - 96.3 1 2 0 -0.0009 8 0 0 0 2.48E+06 3.04E+06 - - - -1.0976 0.9914 221125_WJC_METTL3_EV_vs_WT_F01.05438.05438.2 0.807 12-Jun K.LAEPYGK.L "sp|P43243|MATR3_HUMAN,tr|B3KM87|B3KM87_HUMAN,tr|A8MXP9|A8MXP9_HUMAN,tr|D6RBK5|D6RBK5_HUMAN,tr|A0A0R4J2E8|A0A0R4J2E8_HUMAN,tr|H0Y8T4|H0Y8T4_HUMAN,tr|D6REM6|D6REM6_HUMAN" 7 776.4069 1.6 176 5438 2 776.407714 389.2107 Matrin-3 OS=Homo sapiens OX=9606 GN=MATR3 PE=1 SV=2 6 1746.1 - 351108 - - - 1.1064 - 1.23 0.17 - 153.2 1 2 0 0.0009 7 0 0 0 2.92E+07 1.83E+07 - - - 0.9523 0.9887 221125_WJC_METTL3_EV_vs_WT_F01.05454.05454.2 0.0249 12-Jun K.LAEPYGK[136.11].L "sp|P43243|MATR3_HUMAN,tr|B3KM87|B3KM87_HUMAN,tr|A8MXP9|A8MXP9_HUMAN,tr|D6RBK5|D6RBK5_HUMAN,tr|A0A0R4J2E8|A0A0R4J2E8_HUMAN,tr|H0Y8T4|H0Y8T4_HUMAN,tr|D6REM6|D6REM6_HUMAN" 7 784.4211 1.59 177 5454 2 784.418188 393.2178 Matrin-3 OS=Homo sapiens OX=9606 GN=MATR3 PE=1 SV=2 6 1749 - 468433 - - - -3.6549 - 1.165 0.333 - 133.2 1 2 0 -0.0029 7 0 0 0 2.89E+07 1.83E+07 - - - 1.9835 0.9947 221125_WJC_METTL3_EV_vs_WT_F01.05519.05519.2 0.00358 16-Sep K.SAVEDEGLK[136.11].G "sp|P0DMV8|HS71A_HUMAN,sp|P0DMV9|HS71B_HUMAN,tr|V9GZ37|V9GZ37_HUMAN,tr|A0A0G2JIW1|A0A0G2JIW1_HUMAN" 4 954.4749 0.04 180 5519 2 954.473145 478.2447 Heat shock 70 kDa protein 1A OS=Homo sapiens OX=9606 GN=HSPA1A PE=1 SV=1 4.14 1760.8 - 292955 - - - -1.8817 - 1.708 0.133 - 321.5 1 2 0 -0.0018 9 0 0 0 1.39E+06 3.51E+07 - - - 1.5715 0.9855 221125_WJC_METTL3_EV_vs_WT_F01.05601.05601.2 4.99 14-Jun R.STLEPVEK[136.11].A "sp|P48741|HSP77_HUMAN,sp|P0DMV8|HS71A_HUMAN,sp|P0DMV9|HS71B_HUMAN,sp|P17066|HSP76_HUMAN,tr|V9GZ37|V9GZ37_HUMAN,tr|A0A0G2JIW1|A0A0G2JIW1_HUMAN" 6 909.4899 0.12 181 5601 2 909.490191 455.7522 Putative heat shock 70 kDa protein 7 OS=Homo sapiens OX=9606 GN=HSPA7 PE=5 SV=2 4.53 1776 - 204687 - - - 0.3606 - 1.189 0.114 - 167 1 2 0 0.0003 8 0 0 0 4.43E+06 3.57E+07 - - - 0.405 0.9245 221125_WJC_METTL3_EV_vs_WT_F01.05744.05744.2 3.01 16-Apr R.VTDALNATR[166.11].A "sp|P10809|CH60_HUMAN,tr|A0A7I2V2X6|A0A7I2V2X6_HUMAN,tr|A0A7I2YQK6|A0A7I2YQK6_HUMAN,tr|A0A7I2V599|A0A7I2V599_HUMAN" 4 969.5119 1.29 190 5744 2 969.511028 485.7632 "60 kDa heat shock protein, mitochondrial OS=Homo sapiens OX=9606 GN=HSPD1 PE=1 SV=2" 5.81 1802.6 - 88856.9 - - - -0.8778 - 0.948 0.113 - 43.7 6 2 0 -0.0009 9 0 0 0 6.14E+07 4.76E+07 - - - -0.6267 0.9967 221125_WJC_METTL3_EV_vs_WT_F01.05902.05902.2 0.00437 20-Apr R.ADTQTYQPYNK.D sp|P84090|ERH_HUMAN 1 1327.6044 3.25 199 5902 2 1327.600532 664.8095 Enhancer of rudimentary homolog OS=Homo sapiens OX=9606 GN=ERH PE=1 SV=1 5.88 1830.6 - 57154.1 - - - -2.9474 - 0.976 0.491 - 43.3 1 2 0 -0.0039 11 0 0 0 2.18E+06 6.71E+05 - - - 2.6006 0.9697 221125_WJC_METTL3_EV_vs_WT_F01.05921.05921.2 0.85 18-Jul R.IADGYEQAAR[166.11].V "sp|P48643|TCPE_HUMAN,tr|E9PCA1|E9PCA1_HUMAN,tr|B7ZAR1|B7ZAR1_HUMAN,tr|E7ENZ3|E7ENZ3_HUMAN" 4 1102.5283 0.79 202 5921 2 1102.525393 552.2714 T-complex protein 1 subunit epsilon OS=Homo sapiens OX=9606 GN=CCT5 PE=1 SV=1 4.37 1833.9 - 101497 - - - -2.5977 - 1.14 0.171 - 123.7 1 2 0 -0.0029 10 0 0 0 1.65E+06 2.09E+06 - - - 0.6688 0.984 221125_WJC_METTL3_EV_vs_WT_F01.06003.06003.2 0.119 16-Jun K.GPSSVEDIK[136.11].A "sp|P06748|NPM_HUMAN,tr|E5RI98|E5RI98_HUMAN,tr|A0A7I2YQC0|A0A7I2YQC0_HUMAN,tr|A0A7I2V5J8|A0A7I2V5J8_HUMAN,tr|A0A7I2V5S2|A0A7I2V5S2_HUMAN" 5 938.48 0.17 208 6003 2 938.475859 470.2473 Nucleophosmin OS=Homo sapiens OX=9606 GN=NPM1 PE=1 SV=2 4.37 1848.7 - 160627 - - - -4.4402 - 1.305 0.319 - 132.8 1 2 0 -0.0042 9 0 0 0 9.27E+05 5.31E+06 - - - 2.166 0.9851 221125_WJC_METTL3_EV_vs_WT_F01.06138.06138.2 1.36 14-Jun K.VISELNGK[136.11].N "sp|P05387|RLA2_HUMAN,tr|H0YDD8|H0YDD8_HUMAN" 2 866.4953 1.91 212 6138 2 866.494585 434.2549 60S acidic ribosomal protein P2 OS=Homo sapiens OX=9606 GN=RPLP2 PE=1 SV=1 5.97 1872.9 - 317622 - - - -0.8055 - 1.144 0.132 - 105.1 1 2 0 -0.0007 8 0 0 0 2.47E+07 1.29E+07 - - - 0.4215 0.9966 221125_WJC_METTL3_EV_vs_WT_F01.06142.06142.2 0.154 14-Jun K.VISELNGK.N "sp|P05387|RLA2_HUMAN,tr|H0YDD8|H0YDD8_HUMAN" 2 858.4811 2.61 213 6142 2 858.481322 430.2478 60S acidic ribosomal protein P2 OS=Homo sapiens OX=9606 GN=RPLP2 PE=1 SV=1 5.97 1873.6 - 402608 - - - 0.2784 - 1.215 0.242 - 140.7 1 2 0 0.0002 8 0 0 0 3.37E+07 1.29E+07 - - - 1.4157 0.998 221125_WJC_METTL3_EV_vs_WT_F01.06206.06206.2 0.0125 18-Aug K.AGFAGDDAPR.A "sp|Q6S8J3|POTEE_HUMAN,sp|P63261|ACTG_HUMAN,sp|P68133|ACTS_HUMAN,sp|P62736|ACTA_HUMAN,sp|P68032|ACTC_HUMAN,sp|P60709|ACTB_HUMAN,sp|P63267|ACTH_HUMAN,sp|A5A3E0|POTEF_HUMAN,sp|P0CG38|POTEI_HUMAN,sp|P0CG39|POTEJ_HUMAN,tr|A0A804GS07|A0A804GS07_HUMAN,tr|I3L3I0|I3L3I0_HUMAN,tr|G5E9R0|G5E9R0_HUMAN,tr|E7EVS6|E7EVS6_HUMAN,tr|A0A6Q8PGD7|A0A6Q8PGD7_HUMAN,tr|B8ZZJ2|B8ZZJ2_HUMAN,tr|J3KT65|J3KT65_HUMAN,tr|I3L3R2|I3L3R2_HUMAN,tr|K7EM38|K7EM38_HUMAN,tr|F6QUT6|F6QUT6_HUMAN,tr|C9JTX5|C9JTX5_HUMAN,tr|A0A6Q8PH58|A0A6Q8PH58_HUMAN,tr|F6UVQ4|F6UVQ4_HUMAN,tr|F8WB63|F8WB63_HUMAN,tr|I3L1U9|I3L1U9_HUMAN,tr|A0A2R8Y793|A0A2R8Y793_HUMAN,tr|I3L4N8|I3L4N8_HUMAN,tr|C9JUM1|C9JUM1_HUMAN,tr|F8WCH0|F8WCH0_HUMAN,tr|C9JZR7|C9JZR7_HUMAN,tr|C9JFL5|C9JFL5_HUMAN,tr|A0A2R8YGF8|A0A2R8YGF8_HUMAN,tr|A6NL76|A6NL76_HUMAN,tr|A0A7P0TBL1|A0A7P0TBL1_HUMAN" 34 975.441 3.77 216 6206 2 975.438377 488.7278 POTE ankyrin domain family member E OS=Homo sapiens OX=9606 GN=POTEE PE=2 SV=3 4.21 1885.8 - 215772 - - - -2.6983 - 1.391 0.399 - 170.5 1 2 0 -0.0026 10 0 0 0 9.21E+06 2.44E+06 - - - 2.9084 0.9987 221125_WJC_METTL3_EV_vs_WT_F01.06207.06207.2 0.0321 18-Jun K.YEELQQTAGR.H "sp|P13647|K2C5_HUMAN,tr|H0YI76|H0YI76_HUMAN,tr|H0YIN9|H0YIN9_HUMAN" 3 1193.5677 999 217 6207 2 1193.564627 597.7911 "Keratin, type II cytoskeletal 5 OS=Homo sapiens OX=9606 GN=KRT5 PE=1 SV=3" 4.53 1885.9 - 66067.7 - - - -2.5461 - 1.59 0.391 - 117.2 1 2 0 -0.003 10 0 0 0 2.38E+06 0.00E+00 - - - 3.2224 0.9975 221125_WJC_METTL3_EV_vs_WT_F01.06221.06221.2 0.00494 16-Jul K.SFQQSSLSR[166.11].D "sp|P43243|MATR3_HUMAN,tr|A0A1B0GX04|A0A1B0GX04_HUMAN,tr|D6RBS2|D6RBS2_HUMAN,tr|A8MXP9|A8MXP9_HUMAN,tr|D6R991|D6R991_HUMAN,tr|D6REK4|D6REK4_HUMAN,tr|D6R9F3|D6R9F3_HUMAN,tr|A0A0R4J2E8|A0A0R4J2E8_HUMAN,tr|D6RB45|D6RB45_HUMAN,tr|D6RCM3|D6RCM3_HUMAN,tr|D6R8Z5|D6R8Z5_HUMAN,tr|D6REM6|D6REM6_HUMAN" 12 1048.5177 2.25 218 6221 2 1048.514784 525.2661 Matrin-3 OS=Homo sapiens OX=9606 GN=MATR3 PE=1 SV=2 9.47 1888.4 - 120105 - - - -2.7744 - 1.245 0.414 - 136.1 1 2 0 -0.0029 9 0 0 0 1.89E+07 8.41E+06 - - - 2.7319 0.9681 221125_WJC_METTL3_EV_vs_WT_F01.06323.06323.2 0.0124 16-Jun K.AQYEDIAQK.S sp|P04264|K2C1_HUMAN 1 1064.5138 2.09 227 6323 2 1064.50793 533.2642 "Keratin, type II cytoskeletal 1 OS=Homo sapiens OX=9606 GN=KRT1 PE=1 SV=6" 4.37 1906.2 - 485592 - - - -5.5509 - 1.258 0.344 - 89.2 1 2 0 -0.0059 9 0 0 0 1.84E+07 8.81E+06 - - - 2.244 0.9828 221125_WJC_METTL3_EV_vs_WT_F01.06390.06390.2 0.0243 24-Aug K.GPGEVAGTVTGQK[136.11].R "sp|Q86U44|MTA70_HUMAN,tr|F5H6D8|F5H6D8_HUMAN,tr|H0YFV6|H0YFV6_HUMAN,tr|B4DTN4|B4DTN4_HUMAN" 4 1207.6288 0 232 6390 2 1207.621719 604.8217 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 6 1917.4 - 221252 - - - -5.8768 - 1.675 0.363 - 114.5 1 2 0 -0.0071 13 0 0 0 3.81E+04 4.67E+07 - - - 3.0437 0.9078 221125_WJC_METTL3_EV_vs_WT_F01.06433.06433.2 0.0874 14-Jul R.GTLDPVEK[136.11].A "sp|P11142|HSP7C_HUMAN,tr|E9PNE6|E9PNE6_HUMAN,tr|A8K7Q2|A8K7Q2_HUMAN,tr|E9PKE3|E9PKE3_HUMAN,tr|E9PN89|E9PN89_HUMAN" 5 865.4636 0.21 237 6433 2 865.459973 433.7391 Heat shock cognate 71 kDa protein OS=Homo sapiens OX=9606 GN=HSPA8 PE=1 SV=1 4.37 1924.4 - 685495 - - - -4.2463 - 1.424 0.079 - 201.8 1 2 0 -0.0037 8 0 0 0 1.43E+07 6.67E+07 - - - 0.6894 0.9284 221125_WJC_METTL3_EV_vs_WT_F01.06491.06491.2 9.17 12-May K.IIAPPER.K "sp|P63261|ACTG_HUMAN,sp|P68133|ACTS_HUMAN,sp|P62736|ACTA_HUMAN,sp|P68032|ACTC_HUMAN,sp|Q562R1|ACTBL_HUMAN,sp|P60709|ACTB_HUMAN,sp|P63267|ACTH_HUMAN,tr|A0A2R8YFE2|A0A2R8YFE2_HUMAN,tr|A0A804GS07|A0A804GS07_HUMAN,tr|A0A6Q8PFE4|A0A6Q8PFE4_HUMAN,tr|A0A804HKV3|A0A804HKV3_HUMAN,tr|I3L4N8|I3L4N8_HUMAN" 12 794.465 3.53 241 6491 2 794.464812 398.2398 "Actin, cytoplasmic 2 OS=Homo sapiens OX=9606 GN=ACTG1 PE=1 SV=1" 6 1934.5 - 376085 - - - -0.2845 - 1.025 0.028 - 98.3 1 2 0 -0.0002 7 0 0 0 4.09E+07 1.16E+07 - - - -0.674 0.9879 221125_WJC_METTL3_EV_vs_WT_F01.06511.06511.2 0.635 12-May R.FSGVPDR.F "sp|A0A075B6R9|KVD24_HUMAN,sp|A0A0C4DH68|KV224_HUMAN,sp|A2NJV5|KV229_HUMAN,sp|A0A075B6S2|KVD29_HUMAN,sp|A0A0A0MRZ7|KVD26_HUMAN" 5 776.3817 1741.69 243 6511 2 776.380791 389.1981 Probable non-functional immunoglobulin kappa variable 2D-24 OS=Homo sapiens OX=9606 GN=IGKV2D-24 PE=1 SV=1 5.84 1937.9 - 161839 - - - -1.1747 - 1.134 0.184 - 79.6 2 2 0 -0.0009 7 0 0 0 1.56E+09 8.95E+05 - - - 0.6637 0.998 221125_WJC_METTL3_EV_vs_WT_F01.06572.06572.2 0.261 16-Jun K.SAAMTLNER[166.11].F "sp|Q9NYF8|BCLF1_HUMAN,tr|E9PKI6|E9PKI6_HUMAN,tr|A0A1W2PQ43|A0A1W2PQ43_HUMAN,tr|E9PK91|E9PK91_HUMAN,tr|E9PK09|E9PK09_HUMAN,tr|E9PQN2|E9PQN2_HUMAN" 6 1001.484 2.2 249 6572 2 1001.483032 501.7493 Bcl-2-associated transcription factor 1 OS=Homo sapiens OX=9606 GN=BCLAF1 PE=1 SV=2 5.72 1948.4 - 99291.7 - - - -0.9166 - 1.499 0.227 - 170 1 2 0 -0.0009 9 0 0 0 1.08E+07 4.92E+06 - - - 1.8884 0.9843 221125_WJC_METTL3_EV_vs_WT_F01.06594.06594.2 0.92 18-Aug K.AEAESLYQSK.Y sp|P04264|K2C1_HUMAN 1 1124.535 2.5 253 6594 2 1124.537233 563.2748 "Keratin, type II cytoskeletal 1 OS=Homo sapiens OX=9606 GN=KRT1 PE=1 SV=6" 4.53 1951.8 - 154588 - - - 2.0133 - 1.395 0.124 - 110.3 1 2 0 0.0023 10 0 0 0 5.51E+06 2.20E+06 - - - 0.8854 0.9994 221125_WJC_METTL3_EV_vs_WT_F01.06613.06613.2 0.00246 24-May R.EVATNSELVQSGK.S "sp|Q04695|K1C17_HUMAN,sp|P02533|K1C14_HUMAN,tr|K7ESE1|K7ESE1_HUMAN,tr|F5GWP8|F5GWP8_HUMAN" 4 1360.6834 999 256 6613 2 1360.683911 681.349 "Keratin, type I cytoskeletal 17 OS=Homo sapiens OX=9606 GN=KRT17 PE=1 SV=2" 4.53 1955 - 48754.8 - - - 0.3579 - 1.17 0.468 - 52.5 1 2 0 0.0005 13 0 0 0 2.96E+06 0.00E+00 - - - 2.9004 0.9968 221125_WJC_METTL3_EV_vs_WT_F01.06696.06696.2 0.0124 14-Jul K.GANPVEIR.R "sp|P10809|CH60_HUMAN,tr|A0A7I2V2X6|A0A7I2V2X6_HUMAN,tr|A0A7I2YQK6|A0A7I2YQK6_HUMAN,tr|A0A7I2V599|A0A7I2V599_HUMAN,tr|E7EXB4|E7EXB4_HUMAN,tr|A0A7I2YQ71|A0A7I2YQ71_HUMAN,tr|E7ESH4|E7ESH4_HUMAN,tr|A0A7I2V5M1|A0A7I2V5M1_HUMAN,tr|A0A7I2V5K3|A0A7I2V5K3_HUMAN,tr|A0A7I2V369|A0A7I2V369_HUMAN" 10 854.461 0.91 264 6696 2 854.458714 428.2378 "60 kDa heat shock protein, mitochondrial OS=Homo sapiens OX=9606 GN=HSPD1 PE=1 SV=2" 6 1969.3 - 609365 - - - -2.6941 - 1.282 0.362 - 201.5 1 2 0 -0.0023 8 0 0 0 3.62E+07 3.98E+07 - - - 2.4632 0.9768 221125_WJC_METTL3_EV_vs_WT_F01.06710.06710.2 0.811 12-May R.FSGVPDR.F "sp|A0A075B6R9|KVD24_HUMAN,sp|A0A0C4DH68|KV224_HUMAN,sp|A2NJV5|KV229_HUMAN,sp|A0A075B6S2|KVD29_HUMAN,sp|A0A0A0MRZ7|KVD26_HUMAN" 5 776.3817 189.53 267 6710 2 776.379665 389.1981 Probable non-functional immunoglobulin kappa variable 2D-24 OS=Homo sapiens OX=9606 GN=IGKV2D-24 PE=1 SV=1 5.84 1971.4 - 240028 - - - -2.625 - 1.169 0.199 - 84 2 2 0 -0.002 7 0 0 0 2.67E+07 1.41E+05 - - - 0.8705 0.8425 221125_WJC_METTL3_EV_vs_WT_F01.06723.06723.2 4.79 14-May R.ELTAVVQK[136.11].R "sp|P23396|RS3_HUMAN,tr|E9PL09|E9PL09_HUMAN,tr|E9PK82|E9PK82_HUMAN,tr|F2Z2S8|F2Z2S8_HUMAN,tr|H0YCJ7|H0YCJ7_HUMAN,tr|E9PQ96|E9PQ96_HUMAN,tr|E9PJH4|E9PJH4_HUMAN,tr|E9PPU1|E9PPU1_HUMAN,tr|H0YF32|H0YF32_HUMAN" 9 894.5266 0.57 268 6723 2 894.524431 448.2706 40S ribosomal protein S3 OS=Homo sapiens OX=9606 GN=RPS3 PE=1 SV=2 6.1 1973.6 - 118010 - - - -2.4057 - 1.047 0.053 - 94.5 2 2 0 -0.0022 8 0 0 0 3.20E+06 5.66E+06 - - - -0.5642 0.9122 221125_WJC_METTL3_EV_vs_WT_F01.06728.06728.2 2.6 14-May R.K[136.11]ATC[160.03]LLGR[166.11].S "sp|P19883|FST_HUMAN,tr|H0YA75|H0YA75_HUMAN,tr|H0YAF9|H0YAF9_HUMAN" 3 935.5341 0 269 6728 2 935.531393 468.7743 Follistatin OS=Homo sapiens OX=9606 GN=FST PE=1 SV=2 9.51 1974.4 - 162474 - - - -2.9374 - 1.202 0.068 - 100.2 1 2 0 -0.0027 8 0 0 0 1.24E+04 5.07E+06 - - - 0.0973 0.9961 221125_WJC_METTL3_EV_vs_WT_F01.06737.06737.2 0.0674 14-Jun K.GANPVEIR[166.11].R "sp|P10809|CH60_HUMAN,tr|A0A7I2V2X6|A0A7I2V2X6_HUMAN,tr|A0A7I2YQK6|A0A7I2YQK6_HUMAN,tr|A0A7I2V599|A0A7I2V599_HUMAN,tr|E7EXB4|E7EXB4_HUMAN,tr|A0A7I2YQ71|A0A7I2YQ71_HUMAN,tr|E7ESH4|E7ESH4_HUMAN,tr|A0A7I2V5M1|A0A7I2V5M1_HUMAN,tr|A0A7I2V5K3|A0A7I2V5K3_HUMAN,tr|A0A7I2V369|A0A7I2V369_HUMAN" 10 864.4693 0.9 270 6737 2 864.470595 433.2419 "60 kDa heat shock protein, mitochondrial OS=Homo sapiens OX=9606 GN=HSPD1 PE=1 SV=2" 6 1976 - 348799 - - - 1.5142 - 1.169 0.297 - 158.2 1 2 0 0.0013 8 0 0 0 3.64E+07 4.05E+07 - - - 1.7052 0.9972 221125_WJC_METTL3_EV_vs_WT_F01.06747.06747.2 2.36 14-Sep K.QEIAEINR.M "sp|P48668|K2C6C_HUMAN,sp|P04259|K2C6B_HUMAN,sp|P02538|K2C6A_HUMAN" 3 971.5036 225.73 272 6747 2 971.503023 486.7591 "Keratin, type II cytoskeletal 6C OS=Homo sapiens OX=9606 GN=KRT6C PE=1 SV=3" 4.53 1977.6 - 198692 - - - -0.6032 - 1.617 0.145 - 360.1 1 2 0 -0.0006 8 0 0 0 8.38E+06 3.71E+04 - - - 1.5612 0.9995 221125_WJC_METTL3_EV_vs_WT_F01.06749.06749.2 0.015 14-Aug K.VGEVIVTK[136.11].D "sp|P10809|CH60_HUMAN,tr|A0A7I2V2X6|A0A7I2V2X6_HUMAN,tr|A0A7I2YQK6|A0A7I2YQK6_HUMAN,tr|A0A7I2V599|A0A7I2V599_HUMAN" 4 851.5208 1.21 273 6749 2 851.520407 426.7677 "60 kDa heat shock protein, mitochondrial OS=Homo sapiens OX=9606 GN=HSPD1 PE=1 SV=2" 5.97 1977.8 - 202275 - - - -0.4251 - 1.761 0.31 - 188.9 1 2 0 -0.0004 8 0 0 0 1.01E+08 8.35E+07 - - - 3.0372 0.9998 221125_WJC_METTL3_EV_vs_WT_F01.06765.06765.2 0.0293 14-Oct K.VGEVIVTK.D "sp|P10809|CH60_HUMAN,tr|A0A7I2V2X6|A0A7I2V2X6_HUMAN,tr|A0A7I2YQK6|A0A7I2YQK6_HUMAN,tr|A0A7I2V599|A0A7I2V599_HUMAN" 4 843.5066 1.21 276 6765 2 843.505833 422.7606 "60 kDa heat shock protein, mitochondrial OS=Homo sapiens OX=9606 GN=HSPD1 PE=1 SV=2" 5.97 1980.4 - 911971 - - - -0.8725 - 2.229 0.339 - 291.8 1 2 0 -0.0007 8 0 0 0 1.01E+08 8.35E+07 - - - 3.9621 0.9995 221125_WJC_METTL3_EV_vs_WT_F01.06875.06875.2 0.0116 16-Jul K.AQYEEIAQR.S "sp|P48668|K2C6C_HUMAN,sp|Q01546|K22O_HUMAN,sp|P19013|K2C4_HUMAN,sp|P04259|K2C6B_HUMAN,sp|P35908|K22E_HUMAN,sp|P02538|K2C6A_HUMAN" 6 1106.5356 2.28 286 6875 2 1106.534387 554.2751 "Keratin, type II cytoskeletal 6C OS=Homo sapiens OX=9606 GN=KRT6C PE=1 SV=3" 4.53 1999.2 - 73607 - - - -1.1297 - 1.32 0.456 - 204.3 1 2 0 -0.0013 9 0 0 0 1.48E+07 6.52E+06 - - - 3.2118 0.923 221125_WJC_METTL3_EV_vs_WT_F01.07098.07098.3 0.0627 Aug-44 R.TLVAVKPDGVQR.R "sp|O00746|NDKM_HUMAN,tr|Q4TT34|Q4TT34_HUMAN,tr|A0A087WVT9|A0A087WVT9_HUMAN,tr|H0Y6J0|H0Y6J0_HUMAN,tr|F2Z2X0|F2Z2X0_HUMAN" 5 1281.7405 1.64 308 7098 3 1281.733135 428.2541 "Nucleoside diphosphate kinase, mitochondrial OS=Homo sapiens OX=9606 GN=NME4 PE=1 SV=1" 8.41 2036.8 - 203957 - - - -5.7344 - 1.296 0.295 - 69.7 1 2 0 -0.0073 12 0 0 0 6.96E+06 4.26E+06 - - - 2.5456 0.9428 221125_WJC_METTL3_EV_vs_WT_F01.07099.07099.2 0.0888 14-Jun R.VLLGETGK.E "sp|P62280|RS11_HUMAN,tr|M0QZC5|M0QZC5_HUMAN,tr|M0R1H6|M0R1H6_HUMAN" 3 815.4753 1.03 309 7099 2 815.471807 408.7449 40S ribosomal protein S11 OS=Homo sapiens OX=9606 GN=RPS11 PE=1 SV=3 5.97 2036.9 - 142133 - - - -4.2454 - 1.16 0.211 - 122.9 1 2 0 -0.0035 8 0 0 0 9.02E+06 8.74E+06 - - - 1.046 0.9875 221125_WJC_METTL3_EV_vs_WT_F01.07112.07112.3 0.182 Jul-36 K.ILAHNNFVGR.L "sp|Q9NZI8|IF2B1_HUMAN,sp|O00425|IF2B3_HUMAN" 2 1139.62 0.01 314 7112 3 1139.618245 380.8806 Insulin-like growth factor 2 mRNA-binding protein 1 OS=Homo sapiens OX=9606 GN=IGF2BP1 PE=1 SV=2 9.76 2038.6 - 75443.5 - - - -1.5189 - 1.423 0.203 - 51.5 1 2 0 -0.0017 10 0 0 0 2.06E+06 2.24E+08 - - - 1.833 0.9998 221125_WJC_METTL3_EV_vs_WT_F01.07131.07131.2 0.000124 16-Sep K.VTMQNLNDR.L "sp|P13645|K1C10_HUMAN,sp|Q7Z3Z0|K1C25_HUMAN,sp|Q7Z3Y9|K1C26_HUMAN,sp|P02533|K1C14_HUMAN,sp|Q7Z3Y8|K1C27_HUMAN,sp|P08779|K1C16_HUMAN,sp|Q7Z3Y7|K1C28_HUMAN,tr|A0A1B0GVI3|A0A1B0GVI3_HUMAN" 8 1089.5237 2268.27 318 7131 2 1089.523928 545.7691 "Keratin, type I cytoskeletal 10 OS=Homo sapiens OX=9606 GN=KRT10 PE=1 SV=6" 5.81 2041.7 - 219930 - - - 0.2166 - 1.813 0.431 - 325.8 1 2 0 0.0002 9 0 0 0 2.27E+07 1.00E+04 - - - 3.9456 0.9379 221125_WJC_METTL3_EV_vs_WT_F01.07158.07158.2 0.378 26-Mar R.GFSSGSAVVSGGSR.R sp|P35908|K22E_HUMAN 1 1253.6 999 325 7158 2 1253.602351 627.8073 "Keratin, type II cytoskeletal 2 epidermal OS=Homo sapiens OX=9606 GN=KRT2 PE=1 SV=2" 9.75 2046 - 33192 - - - 1.8523 - 0.731 0.221 - 14.2 1 2 0 0.0023 14 0 0 0 1.53E+06 0.00E+00 - - - -0.1137 0.9988 221125_WJC_METTL3_EV_vs_WT_F01.07240.07240.2 0.0191 20-Jun R.VEIIANDQGNR[166.11].L "sp|P11021|BIP_HUMAN,sp|P48741|HSP77_HUMAN,sp|P54652|HSP72_HUMAN,sp|P0DMV8|HS71A_HUMAN,sp|P34931|HS71L_HUMAN,sp|P11142|HSP7C_HUMAN,sp|P0DMV9|HS71B_HUMAN,sp|P17066|HSP76_HUMAN,tr|E9PQQ4|E9PQQ4_HUMAN,tr|E9PNE6|E9PNE6_HUMAN,tr|E9PKE3|E9PKE3_HUMAN,tr|A0A7P0TB36|A0A7P0TB36_HUMAN,tr|E9PLF4|E9PLF4_HUMAN,tr|A0A7P0TAI0|A0A7P0TAI0_HUMAN,tr|Q53FA3|Q53FA3_HUMAN,tr|E9PI65|E9PI65_HUMAN,tr|E9PK54|E9PK54_HUMAN,tr|E9PN25|E9PN25_HUMAN,tr|E9PPY6|E9PPY6_HUMAN,tr|E9PQK7|E9PQK7_HUMAN,tr|A0A0G2JIW1|A0A0G2JIW1_HUMAN" 21 1237.629 0.15 339 7240 2 1237.628239 619.8218 Endoplasmic reticulum chaperone BiP OS=Homo sapiens OX=9606 GN=HSPA5 PE=1 SV=2 4.37 2059.4 - 80195.8 - - - -0.6424 - 1.569 0.274 - 109.8 1 2 0 -0.0008 11 0 0 0 1.23E+06 8.34E+06 - - - 2.2831 0.9964 221125_WJC_METTL3_EV_vs_WT_F01.07293.07293.2 0.128 14-Aug R.FSELTAEK.L "sp|P48643|TCPE_HUMAN,tr|E9PCA1|E9PCA1_HUMAN,tr|B7ZAR1|B7ZAR1_HUMAN,tr|E7ENZ3|E7ENZ3_HUMAN" 4 923.46 0.65 345 7293 2 923.459281 462.7373 T-complex protein 1 subunit epsilon OS=Homo sapiens OX=9606 GN=CCT5 PE=1 SV=1 4.53 2068.4 - 172249 - - - -0.7927 - 1.505 0.154 - 162.4 1 2 0 -0.0007 8 0 0 0 7.81E+06 1.20E+07 - - - 1.4111 0.9979 221125_WJC_METTL3_EV_vs_WT_F01.07326.07326.2 0.996 18-May R.YPDGIISK[136.11]PK[136.11].N sp|Q86U44|MTA70_HUMAN 1 1132.6463 0 350 7326 2 1132.647298 567.3304 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 8.5 2074.3 - 108552 - - - 0.8723 - 1.327 0.315 - 61.8 3 2 0 0.001 10 0 0 0 1.32E+05 6.11E+07 - - - 1.9439 0.9863 221125_WJC_METTL3_EV_vs_WT_F01.07349.07349.2 1.19 12-Apr R.EIAQDFK.T "sp|Q16695|H31T_HUMAN,sp|P84243|H33_HUMAN,sp|Q71DI3|H32_HUMAN,sp|P68431|H31_HUMAN,tr|B4DEB1|B4DEB1_HUMAN,tr|K7EK07|K7EK07_HUMAN,tr|K7ES00|K7ES00_HUMAN,tr|K7EMV3|K7EMV3_HUMAN,tr|A0A590UJJ6|A0A590UJJ6_HUMAN" 9 849.4232 1.06 354 7349 2 849.423596 425.7189 Histone H3.1t OS=Homo sapiens OX=9606 GN=H3-4 PE=1 SV=3 4.37 2078.4 - 251810 - - - 0.4273 - 0.922 0.226 - 99.6 1 2 0 0.0004 7 0 0 0 9.58E+06 9.00E+06 - - - 0.4528 0.9974 221125_WJC_METTL3_EV_vs_WT_F01.07358.07358.2 0.0246 16-Jun K.DVDGAYMTK.V sp|P04264|K2C1_HUMAN 1 998.4379 1.67 356 7358 2 998.438882 500.2262 "Keratin, type II cytoskeletal 1 OS=Homo sapiens OX=9606 GN=KRT1 PE=1 SV=6" 4.21 2079.9 - 277971 - - - 0.9865 - 1.235 0.289 - 75.5 1 2 0 0.001 9 0 0 0 1.43E+07 8.58E+06 - - - 1.7859 0.9709 221125_WJC_METTL3_EV_vs_WT_F01.07368.07368.2 0.0244 16-Sep Y.PDGIISK[136.11]PK[136.11].N sp|Q86U44|MTA70_HUMAN 1 969.583 0.001 357 7368 2 969.584378 485.7988 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 9.01 2081.8 - 423630 - - - 1.4398 - 1.871 0.368 - 249.9 1 1 0 0.0014 9 0 0 0 0.00E+00 2.31E+07 - - - 3.571 0.8055 221125_WJC_METTL3_EV_vs_WT_F01.07384.07384.2 0.225 12-May M.VSMVMDR[166.11].E "sp|Q9UJ98|STAG3_HUMAN,tr|D6W5U7|D6W5U7_HUMAN" 2 846.3967 1.47 361 7384 2 846.397412 424.2056 Cohesin subunit SA-3 OS=Homo sapiens OX=9606 GN=STAG3 PE=1 SV=2 5.81 2084.4 - 211580 - - - 0.8247 - 1.197 0.244 - 106.4 1 1 0 0.0007 7 0 0 0 2.00E+08 1.36E+08 - - - 1.4127 0.9992 221125_WJC_METTL3_EV_vs_WT_F01.07435.07435.2 0.00643 16-Sep R.TLLEGEESR.M sp|P04264|K2C1_HUMAN 1 1032.5088 680.59 368 7435 2 1032.507269 517.2617 "Keratin, type II cytoskeletal 1 OS=Homo sapiens OX=9606 GN=KRT1 PE=1 SV=6" 4.25 2093.1 - 1.09E+06 - - - -1.4382 - 1.525 0.368 - 260.1 1 2 0 -0.0015 9 0 0 0 7.21E+07 1.06E+05 - - - 2.9794 0.9991 221125_WJC_METTL3_EV_vs_WT_F01.07537.07537.2 0.00434 20-Jul R.ISSVLAGGSC[160.03]R.A "sp|P02533|K1C14_HUMAN,sp|P08779|K1C16_HUMAN,tr|K7ENV3|K7ENV3_HUMAN" 3 1105.555 999 379 7537 2 1105.553481 553.7848 "Keratin, type I cytoskeletal 14 OS=Homo sapiens OX=9606 GN=KRT14 PE=1 SV=4" 8.25 2110.6 - 285361 - - - -1.3676 - 1.562 0.348 - 88 1 2 0 -0.0015 11 0 0 0 1.83E+07 0.00E+00 - - - 2.8173 0.9969 221125_WJC_METTL3_EV_vs_WT_F01.07574.07574.2 0.0557 16-May K.DVDAAYMNK.V "sp|P48668|K2C6C_HUMAN,sp|P04259|K2C6B_HUMAN,sp|P13647|K2C5_HUMAN,sp|Q14CN4|K2C72_HUMAN,sp|O95678|K2C75_HUMAN,sp|P02538|K2C6A_HUMAN,tr|F8W0C6|F8W0C6_HUMAN,tr|H0YIN9|H0YIN9_HUMAN" 8 1025.4488 347.23 383 7574 2 1025.448265 513.7317 "Keratin, type II cytoskeletal 6C OS=Homo sapiens OX=9606 GN=KRT6C PE=1 SV=3" 4.21 2116.9 - 111755 - - - -0.5178 - 0.969 0.359 - 61.5 2 2 0 -0.0005 9 0 0 0 6.68E+06 1.92E+04 - - - 1.4668 0.9869 221125_WJC_METTL3_EV_vs_WT_F01.07620.07620.2 2.26 12-Jun K.VLAAVYK.A "sp|P05062|ALDOB_HUMAN,sp|P04075|ALDOA_HUMAN,sp|P09972|ALDOC_HUMAN,tr|H3BU78|H3BU78_HUMAN,tr|H3BQN4|H3BQN4_HUMAN,tr|A8MVZ9|A8MVZ9_HUMAN,tr|A0A3B3IS80|A0A3B3IS80_HUMAN,tr|J3KPS3|J3KPS3_HUMAN,tr|A0A087WXX2|A0A087WXX2_HUMAN,tr|H3BPS8|H3BPS8_HUMAN" 10 762.464 2.38 390 7620 2 762.463051 382.2393 Fructose-bisphosphate aldolase B OS=Homo sapiens OX=9606 GN=ALDOB PE=1 SV=2 8.56 2124.4 - 113278 - - - -1.2132 - 1.19 0.14 - 120.8 1 2 0 -0.0009 7 0 0 0 1.29E+08 5.41E+07 - - - 0.6259 0.9999 221125_WJC_METTL3_EV_vs_WT_F01.07631.07631.3 0.000111 Dec-60 K.ATAGDTHLGGEDFDNR.L "sp|P48741|HSP77_HUMAN,sp|P0DMV8|HS71A_HUMAN,sp|P34931|HS71L_HUMAN,sp|P0DMV9|HS71B_HUMAN,sp|P17066|HSP76_HUMAN,tr|Q53FA3|Q53FA3_HUMAN,tr|V9GZ37|V9GZ37_HUMAN,tr|A0A0G2JIW1|A0A0G2JIW1_HUMAN" 8 1674.7234 15.43 392 7631 3 1674.719794 559.2484 Putative heat shock 70 kDa protein 7 OS=Homo sapiens OX=9606 GN=HSPA7 PE=5 SV=2 4.22 2126.1 - 728970 - - - -2.1478 - 1.861 0.527 - 88.1 1 2 0 -0.0036 16 0 0 0 1.24E+07 8.01E+05 - - - 6.0082 0.9801 221125_WJC_METTL3_EV_vs_WT_F01.07636.07636.2 0.309 12-Jul K.VLAAVYK[136.11].A "sp|P05062|ALDOB_HUMAN,sp|P04075|ALDOA_HUMAN,sp|P09972|ALDOC_HUMAN,tr|H3BU78|H3BU78_HUMAN,tr|H3BQN4|H3BQN4_HUMAN,tr|A8MVZ9|A8MVZ9_HUMAN,tr|A0A3B3IS80|A0A3B3IS80_HUMAN,tr|J3KPS3|J3KPS3_HUMAN,tr|A0A087WXX2|A0A087WXX2_HUMAN,tr|H3BPS8|H3BPS8_HUMAN" 10 770.4782 2.38 393 7636 2 770.475976 386.2464 Fructose-bisphosphate aldolase B OS=Homo sapiens OX=9606 GN=ALDOB PE=1 SV=2 8.56 2126.9 - 449394 - - - -2.8554 - 1.362 0.146 - 181.4 1 2 0 -0.0022 7 0 0 0 1.29E+08 5.41E+07 - - - 1.0976 0.9429 221125_WJC_METTL3_EV_vs_WT_F01.07667.07667.2 1.2 14-May K.YENEVALR.Q "sp|P13645|K1C10_HUMAN,tr|A0A1B0GVI3|A0A1B0GVI3_HUMAN" 2 992.4927 1.67 398 7667 2 992.490049 497.2536 "Keratin, type I cytoskeletal 10 OS=Homo sapiens OX=9606 GN=KRT10 PE=1 SV=6" 4.53 2131.9 - 96838.2 - - - -2.6811 - 1.04 0.169 - 48.1 2 2 0 -0.0027 8 0 0 0 6.78E+06 4.07E+06 - - - 0.2722 0.8853 221125_WJC_METTL3_EV_vs_WT_F01.07668.07668.2 9.05 16-May R.AEDAVEAIR[166.11].G "sp|Q9BWF3|RBM4_HUMAN,sp|Q9BQ04|RBM4B_HUMAN,tr|E9PM61|E9PM61_HUMAN,tr|D6R9K7|D6R9K7_HUMAN,tr|J3QRR5|J3QRR5_HUMAN,tr|E9PB51|E9PB51_HUMAN,tr|U3KQD5|U3KQD5_HUMAN,tr|E9PLB0|E9PLB0_HUMAN" 8 982.4959 1.67 399 7668 2 982.495059 492.2552 RNA-binding protein 4 OS=Homo sapiens OX=9606 GN=RBM4 PE=1 SV=1 4.14 2132 - 54209.4 - - - -0.8499 - 0.983 0.049 - 68.6 4 2 0 -0.0008 9 0 0 0 4.05E+06 2.43E+06 - - - -0.9159 0.9916 221125_WJC_METTL3_EV_vs_WT_F01.07693.07693.2 0.0381 12-May R.SNWQNYR.Q "sp|Q9Y2W1|TR150_HUMAN,tr|A0A3B3ITZ9|A0A3B3ITZ9_HUMAN" 2 966.4308 0.64 403 7693 2 966.429378 484.2227 Thyroid hormone receptor-associated protein 3 OS=Homo sapiens OX=9606 GN=THRAP3 PE=1 SV=2 8.46 2136.2 - 169912 - - - -1.4486 - 1.041 0.251 - 89.3 1 2 0 -0.0014 7 0 0 0 5.88E+06 9.22E+06 - - - 1.0218 0.994 221125_WJC_METTL3_EV_vs_WT_F01.07711.07711.2 1.33 12-Aug R.LLAVAER[166.11].Y sp|Q06609|RAD51_HUMAN 1 780.4733 0.73 408 7711 2 780.473402 391.2439 DNA repair protein RAD51 homolog 1 OS=Homo sapiens OX=9606 GN=RAD51 PE=1 SV=1 6 2138.9 - 344580 - - - 0.1204 - 1.542 0.077 - 215.1 1 2 0 0.0001 7 0 0 0 1.01E+07 1.38E+07 - - - 0.9819 0.9664 221125_WJC_METTL3_EV_vs_WT_F01.07716.07716.2 5.68 16-May R.VPPPPPIAR.A "sp|P07910|HNRPC_HUMAN,tr|B4DY08|B4DY08_HUMAN,tr|G3V575|G3V575_HUMAN,tr|G3V5V7|G3V5V7_HUMAN,tr|B2R5W2|B2R5W2_HUMAN,tr|G3V4C1|G3V4C1_HUMAN,tr|G3V576|G3V576_HUMAN,tr|G3V2D6|G3V2D6_HUMAN,tr|G3V4W0|G3V4W0_HUMAN,tr|G3V555|G3V555_HUMAN,tr|G3V2Q1|G3V2Q1_HUMAN" 11 942.5651 1.26 411 7716 2 942.566406 472.2898 Heterogeneous nuclear ribonucleoproteins C1\C2 OS=Homo sapiens OX=9606 GN=HNRNPC PE=1 SV=4 9.72 2139.5 - 110433 - - - 1.3994 - 1.031 0.135 - 101 1 2 0 0.0013 9 0 0 0 1.61E+07 1.28E+07 - - - 0.126 0.9993 221125_WJC_METTL3_EV_vs_WT_F01.07731.07731.2 0.0263 18-Nov K.LLNTVEETTK.D "sp|P52732|KIF11_HUMAN,tr|A0A7I2YQY4|A0A7I2YQY4_HUMAN,tr|A0A7I2V3A9|A0A7I2V3A9_HUMAN" 3 1146.6132 14.42 414 7731 2 1146.61596 574.3139 Kinesin-like protein KIF11 OS=Homo sapiens OX=9606 GN=KIF11 PE=1 SV=2 4.53 2142 - 369815 - - - 2.3905 - 2.019 0.378 - 339.8 1 2 0 0.0027 10 0 0 0 1.21E+07 8.39E+05 - - - 3.7932 0.968 221125_WJC_METTL3_EV_vs_WT_F01.07766.07766.2 2.16 14-May R.EFIQEPAK.N "sp|O14744|ANM5_HUMAN,tr|C9JSX3|C9JSX3_HUMAN,tr|G3V580|G3V580_HUMAN,tr|G3V2L6|G3V2L6_HUMAN,tr|G3V5L5|G3V5L5_HUMAN" 5 960.4916 5.42 423 7766 2 960.490175 481.2531 Protein arginine N-methyltransferase 5 OS=Homo sapiens OX=9606 GN=PRMT5 PE=1 SV=4 4.53 2147.6 - 144422 - - - -1.5325 - 1.113 0.124 - 78.8 2 2 0 -0.0015 8 0 0 0 9.17E+06 1.69E+06 - - - 0.1448 0.9518 221125_WJC_METTL3_EV_vs_WT_F01.07775.07775.2 1.96 14-May R.IVVAAVAR[166.11].A "sp|Q7Z2T5|TRM1L_HUMAN,tr|X6RK96|X6RK96_HUMAN" 2 807.5206 0.62 425 7775 2 807.519328 404.7676 TRMT1-like protein OS=Homo sapiens OX=9606 GN=TRMT1L PE=1 SV=2 9.75 2149 - 287130 - - - -1.5665 - 0.975 0.143 - 76.4 2 2 0 -0.0013 8 0 0 0 8.82E+06 1.41E+07 - - - -0.114 0.9975 221125_WJC_METTL3_EV_vs_WT_F01.07846.07846.2 0.136 18-Jun R.GLDNTEFQGK.R "sp|Q9BWF3|RBM4_HUMAN,sp|Q9BQ04|RBM4B_HUMAN,tr|E9PB51|E9PB51_HUMAN" 3 1107.5197 1.52 440 7846 2 1107.52153 554.7671 RNA-binding protein 4 OS=Homo sapiens OX=9606 GN=RBM4 PE=1 SV=1 4.37 2161 - 94196 - - - 1.6948 - 0.921 0.452 - 66.5 1 2 0 0.0019 10 0 0 0 4.04E+06 2.65E+06 - - - 2.1492 0.9985 221125_WJC_METTL3_EV_vs_WT_F01.07875.07875.2 0.0726 14-May R.DC[160.03]LINAAK[136.11].T "sp|P17987|TCPA_HUMAN,tr|F5H136|F5H136_HUMAN,tr|F5H7Y1|F5H7Y1_HUMAN,tr|E7ERF2|E7ERF2_HUMAN" 4 911.4626 0.41 447 7875 2 911.461547 456.7386 T-complex protein 1 subunit alpha OS=Homo sapiens OX=9606 GN=TCP1 PE=1 SV=1 5.83 2165.5 - 86067.5 - - - -1.1575 - 1.131 0.38 - 68 1 2 0 -0.0011 8 0 0 0 1.09E+06 2.62E+06 - - - 2.2186 0.9325 221125_WJC_METTL3_EV_vs_WT_F01.08034.08034.2 0.000171 20-Aug K.FAEALGSTEAK[136.11].A "sp|P78347|GTF2I_HUMAN,tr|A0A494C0Q7|A0A494C0Q7_HUMAN,tr|A0A494C1K3|A0A494C1K3_HUMAN" 3 1130.5699 2.25 473 8034 2 1130.559535 566.2922 General transcription factor II-I OS=Homo sapiens OX=9606 GN=GTF2I PE=1 SV=2 4.53 2191.3 - 84163.9 - - - -9.1715 - 1.427 0.426 - 146.5 1 2 0 -0.0104 11 0 0 0 3.71E+06 1.65E+06 - - - 3.1461 0.9965 221125_WJC_METTL3_EV_vs_WT_F01.08044.08044.2 0.244 12-May K.DNNLLGR[166.11].F "sp|P0DMV8|HS71A_HUMAN,sp|P34931|HS71L_HUMAN,sp|P0DMV9|HS71B_HUMAN,sp|P17066|HSP76_HUMAN,tr|Q53FA3|Q53FA3_HUMAN,tr|V9GZ37|V9GZ37_HUMAN,tr|A0A0G2JIW1|A0A0G2JIW1_HUMAN" 7 810.4223 0.23 476 8044 2 810.423603 406.2184 Heat shock 70 kDa protein 1A OS=Homo sapiens OX=9606 GN=HSPA1A PE=1 SV=1 5.84 2192.7 - 212524 - - - 1.5634 - 1.326 0.283 - 136.3 3 2 0 0.0013 7 0 0 0 2.39E+06 1.02E+07 - - - 1.8118 0.9661 221125_WJC_METTL3_EV_vs_WT_F01.08074.08074.2 1.48 14-Apr K.VGVNGFGR[166.11].L sp|P04406|G3P_HUMAN 1 814.4325 0.57 481 8074 2 814.432084 408.2235 Glyceraldehyde-3-phosphate dehydrogenase OS=Homo sapiens OX=9606 GN=GAPDH PE=1 SV=3 9.72 2197.7 - 102916 - - - -0.5182 - 0.932 0.165 - 40.7 3 2 0 -0.0004 8 0 0 0 9.49E+06 1.65E+07 - - - -0.166 0.9968 221125_WJC_METTL3_EV_vs_WT_F01.08099.08099.2 0.244 14-Jun K.VGVNGFGR.L sp|P04406|G3P_HUMAN 1 804.4242 0.68 483 8099 2 804.42276 403.2194 Glyceraldehyde-3-phosphate dehydrogenase OS=Homo sapiens OX=9606 GN=GAPDH PE=1 SV=3 9.72 2202.1 - 261950 - - - -1.8349 - 1.385 0.258 - 98.6 1 2 0 -0.0015 8 0 0 0 9.22E+06 1.36E+07 - - - 1.9284 0.8839 221125_WJC_METTL3_EV_vs_WT_F01.08113.08113.2 1.11 12-Mar K.IFC[160.03]ASSR.L "sp|A6NES4|MRO2A_HUMAN,tr|A0A087WT58|A0A087WT58_HUMAN" 2 839.396 100.02 485 8113 2 839.396387 420.7053 Maestro heat-like repeat-containing protein family member 2A OS=Homo sapiens OX=9606 GN=MROH2A PE=4 SV=4 8.25 2204.4 - 292534 - - - 0.4932 - 0.732 0.19 - 17.1 8 2 0 0.0004 7 0 0 0 1.49E+07 1.49E+05 - - - -0.9477 0.9917 221125_WJC_METTL3_EV_vs_WT_F01.08128.08128.2 0.776 16-May R.ILQDSLGGR.T "sp|P52732|KIF11_HUMAN,tr|A0A7I2YQY4|A0A7I2YQY4_HUMAN,tr|A0A7I2V3A9|A0A7I2V3A9_HUMAN,tr|A0A7I2V3V3|A0A7I2V3V3_HUMAN" 4 957.5243 5.57 489 8128 2 957.523525 479.7694 Kinesin-like protein KIF11 OS=Homo sapiens OX=9606 GN=KIF11 PE=1 SV=2 5.84 2206.6 - 123695 - - - -0.8553 - 0.966 0.256 - 62.1 1 2 0 -0.0008 9 0 0 0 4.17E+06 7.49E+05 - - - 0.8315 0.9992 221125_WJC_METTL3_EV_vs_WT_F01.08373.08373.2 1.62E-06 22-Oct K.GSFSDTGLGDGK.M "sp|Q9Y2W1|TR150_HUMAN,tr|A0A3B3ITZ9|A0A3B3ITZ9_HUMAN" 2 1139.5095 2.7 519 8373 2 1139.505122 570.762 Thyroid hormone receptor-associated protein 3 OS=Homo sapiens OX=9606 GN=THRAP3 PE=1 SV=2 4.21 2247.5 - 541613 - - - -3.8262 - 1.899 0.613 - 227.4 1 2 0 -0.0044 12 0 0 0 3.33E+07 1.23E+07 - - - 5.2547 0.9985 221125_WJC_METTL3_EV_vs_WT_F01.08394.08394.2 0.000203 22-Sep K.GSFSDTGLGDGK[136.11].M "sp|Q9Y2W1|TR150_HUMAN,tr|A0A3B3ITZ9|A0A3B3ITZ9_HUMAN" 2 1147.5237 2.7 523 8394 2 1147.51979 574.7691 Thyroid hormone receptor-associated protein 3 OS=Homo sapiens OX=9606 GN=THRAP3 PE=1 SV=2 4.21 2250.7 - 298454 - - - -3.3917 - 1.579 0.48 - 126 1 2 0 -0.0039 12 0 0 0 3.33E+07 1.23E+07 - - - 3.787 0.9988 221125_WJC_METTL3_EV_vs_WT_F01.08400.08400.2 0.000106 16-Oct R.LENEIQTYR.S "sp|P13645|K1C10_HUMAN,tr|A0A1B0GVI3|A0A1B0GVI3_HUMAN" 2 1164.5775 2.91 527 8400 2 1164.575911 583.296 "Keratin, type I cytoskeletal 10 OS=Homo sapiens OX=9606 GN=KRT10 PE=1 SV=6" 4.53 2251.4 - 612946 - - - -1.3662 - 1.809 0.243 - 197.6 1 2 0 -0.0016 9 0 0 0 1.74E+07 5.97E+06 - - - 2.5502 0.9662 221125_WJC_METTL3_EV_vs_WT_F01.08403.08403.2 1.32 12-Jun K.IIDAALR[166.11].A "sp|P20674|COX5A_HUMAN,tr|H3BNX8|H3BNX8_HUMAN,tr|H3BV69|H3BV69_HUMAN,tr|H3BRM5|H3BRM5_HUMAN" 4 780.4733 1.83 528 8403 2 780.470881 391.2439 "Cytochrome c oxidase subunit 5A, mitochondrial OS=Homo sapiens OX=9606 GN=COX5A PE=1 SV=2" 5.84 2251.8 - 690971 - - - -3.1097 - 1.317 0.127 - 95.1 1 2 0 -0.0024 7 0 0 0 1.81E+09 9.90E+08 - - - 0.8507 0.9864 221125_WJC_METTL3_EV_vs_WT_F01.08414.08414.2 0.0845 12-Aug K.IIDAALR.A "sp|P20674|COX5A_HUMAN,tr|H3BNX8|H3BNX8_HUMAN,tr|H3BV69|H3BV69_HUMAN,tr|H3BRM5|H3BRM5_HUMAN" 4 770.465 1.83 530 8414 2 770.462118 386.2398 "Cytochrome c oxidase subunit 5A, mitochondrial OS=Homo sapiens OX=9606 GN=COX5A PE=1 SV=2" 5.84 2253.6 - 3.06E+06 - - - -3.7899 - 1.506 0.213 - 193.5 1 2 0 -0.0029 7 0 0 0 1.81E+09 9.89E+08 - - - 1.9107 0.9685 221125_WJC_METTL3_EV_vs_WT_F01.08458.08458.2 0.0419 26-Feb R.SSFYPDGGDQETAK.T "sp|Q9NYF8|BCLF1_HUMAN,tr|H0YF00|H0YF00_HUMAN,tr|E9PKI6|E9PKI6_HUMAN,tr|A0A1W2PQ43|A0A1W2PQ43_HUMAN,tr|E9PK91|E9PK91_HUMAN,tr|E9PJA7|E9PJA7_HUMAN,tr|E9PK09|E9PK09_HUMAN,tr|E9PQN2|E9PQN2_HUMAN" 8 1500.6369 5.15 537 8458 2 1500.632755 751.3257 Bcl-2-associated transcription factor 1 OS=Homo sapiens OX=9606 GN=BCLAF1 PE=1 SV=2 4.03 2260.7 - 89183.8 - - - -2.7408 - 0.604 0.398 - 6.7 1 2 0 -0.0041 14 0 0 0 1.92E+06 3.73E+05 - - - 0.7141 0.9377 221125_WJC_METTL3_EV_vs_WT_F01.08474.08474.2 0.39 12-Jul R.LAADDFR.T "sp|Q04695|K1C17_HUMAN,sp|P13645|K1C10_HUMAN,sp|O76015|KRT38_HUMAN,sp|Q2M2I5|K1C24_HUMAN,sp|Q15323|K1H1_HUMAN,sp|P02533|K1C14_HUMAN,sp|P05783|K1C18_HUMAN,sp|P08727|K1C19_HUMAN,sp|P08779|K1C16_HUMAN,sp|Q7Z3Y7|K1C28_HUMAN,sp|Q14532|K1H2_HUMAN,sp|P19012|K1C15_HUMAN,sp|O76013|KRT36_HUMAN,sp|Q14525|KT33B_HUMAN,sp|Q92764|KRT35_HUMAN,sp|O76014|KRT37_HUMAN,sp|P13646|K1C13_HUMAN,tr|F8VZY9|F8VZY9_HUMAN,tr|K7EPJ9|K7EPJ9_HUMAN,tr|C9JM50|C9JM50_HUMAN,tr|A0A1B0GVI3|A0A1B0GVI3_HUMAN,tr|K7EMD9|K7EMD9_HUMAN,tr|F5GWP8|F5GWP8_HUMAN,tr|K7ERE3|K7ERE3_HUMAN,tr|C4AM86|C4AM86_HUMAN" 25 806.3923 3.2 539 8474 2 806.386977 404.2034 "Keratin, type I cytoskeletal 17 OS=Homo sapiens OX=9606 GN=KRT17 PE=1 SV=2" 4.21 2263.3 - 421715 - - - -6.5601 - 1.511 0.256 - 205.4 1 2 0 -0.0053 7 0 0 0 4.88E+07 1.52E+07 - - - 2.238 0.8211 221125_WJC_METTL3_EV_vs_WT_F01.08557.08557.2 2.25 12-Jun R.LVGEIVR[166.11].R "sp|Q13232|NDK3_HUMAN,sp|Q15021|CND1_HUMAN,sp|Q3MIP1|IPIL2_HUMAN,tr|H3BRA8|H3BRA8_HUMAN,tr|H3BMQ7|H3BMQ7_HUMAN,tr|H3BPD9|H3BPD9_HUMAN,tr|E7EN77|E7EN77_HUMAN" 7 794.489 3.4 551 8557 2 794.486005 398.2518 Nucleoside diphosphate kinase 3 OS=Homo sapiens OX=9606 GN=NME3 PE=1 SV=2 6 2276.8 - 3.00E+06 - - - -3.7181 - 1.275 0.036 - 133.4 2 2 0 -0.003 7 0 0 0 4.86E+08 1.43E+08 - - - -0.0587 0.9859 221125_WJC_METTL3_EV_vs_WT_F01.08559.08559.3 0.0103 Jul-36 R.LKYENEVALR.Q "sp|P13645|K1C10_HUMAN,tr|A0A1B0GVI3|A0A1B0GVI3_HUMAN" 2 1233.6717 1.06 552 8559 3 1233.667299 412.2312 "Keratin, type I cytoskeletal 10 OS=Homo sapiens OX=9606 GN=KRT10 PE=1 SV=6" 6.14 2277 - 325820 - - - -3.5974 - 1.639 0.34 - 65.3 1 2 1 -0.0044 10 0 0 0 3.80E+07 3.59E+07 - - - 3.7724 0.9984 221125_WJC_METTL3_EV_vs_WT_F01.08570.08570.2 1.64E-06 28-Sep R.APSTYGGGLSVSSSR.F sp|P02533|K1C14_HUMAN 1 1424.6896 999 554 8570 2 1424.683135 713.3521 "Keratin, type I cytoskeletal 14 OS=Homo sapiens OX=9606 GN=KRT14 PE=1 SV=4" 8.79 2278.7 - 102758 - - - -4.5182 - 2.155 0.545 - 201.2 1 2 0 -0.0064 15 0 0 0 3.51E+06 0.00E+00 - - - 4.952 0.9882 221125_WJC_METTL3_EV_vs_WT_F01.08624.08624.2 0.613 20-Jul K.ALAAAGYDVEK.N "sp|P10412|H14_HUMAN,sp|Q02539|H11_HUMAN,sp|P22492|H1T_HUMAN,sp|P16403|H12_HUMAN,sp|P16402|H13_HUMAN" 5 1106.5608 1.74 571 8624 2 1106.563165 554.2877 Histone H1.4 OS=Homo sapiens OX=9606 GN=H1-4 PE=1 SV=2 4.37 2286.8 - 99819.1 - - - 2.1472 - 1.521 0.132 - 125.9 1 2 0 0.0024 11 0 0 0 4.22E+06 2.42E+06 - - - 1.1497 0.9999 221125_WJC_METTL3_EV_vs_WT_F01.08646.08646.3 0.000319 13/44 R.DNIQGITK[136.11]PAIR[166.11].R sp|P62805|H4_HUMAN 1 1342.7688 1.42 576 8646 3 1342.768924 448.5969 Histone H4 OS=Homo sapiens OX=9606 GN=H4C1 PE=1 SV=2 8.75 2290.6 - 239332 - - - 0.1154 - 2.031 0.449 - 246.4 1 2 0 0.0002 12 0 0 0 1.09E+07 7.70E+06 - - - 5.5098 0.9729 221125_WJC_METTL3_EV_vs_WT_F01.08650.08650.2 0.125 16-Aug R.LEQEIATYR.R "sp|Q04695|K1C17_HUMAN,sp|P02533|K1C14_HUMAN,sp|P08727|K1C19_HUMAN,sp|P35900|K1C20_HUMAN,sp|P08779|K1C16_HUMAN,sp|P19012|K1C15_HUMAN,sp|Q8N1A0|KT222_HUMAN,sp|P13646|K1C13_HUMAN,tr|A0A3B3IS58|A0A3B3IS58_HUMAN,tr|F5GWP8|F5GWP8_HUMAN,tr|K7ERE3|K7ERE3_HUMAN,tr|A8MT21|A8MT21_HUMAN" 12 1121.5717 999 578 8650 2 1121.575986 561.7931 "Keratin, type I cytoskeletal 17 OS=Homo sapiens OX=9606 GN=KRT17 PE=1 SV=2" 4.53 2291.1 - 162023 - - - 3.8321 - 1.64 0.127 - 201.6 1 2 0 0.0043 9 0 0 0 9.85E+06 0.00E+00 - - - 1.4089 0.9994 221125_WJC_METTL3_EV_vs_WT_F01.08662.08662.2 0.00945 26-Jul R.APSTYGGGLSVSSR.F sp|P08779|K1C16_HUMAN 1 1337.6575 999 581 8662 2 1337.656083 669.836 "Keratin, type I cytoskeletal 16 OS=Homo sapiens OX=9606 GN=KRT16 PE=1 SV=4" 8.79 2293 - 82970.6 - - - -1.0915 - 1.488 0.414 - 113.7 1 2 0 -0.0015 14 0 0 0 4.95E+06 0.00E+00 - - - 3.0957 0.9993 221125_WJC_METTL3_EV_vs_WT_F01.08676.08676.2 0.00686 12-Jul R.FANYIDK[136.11].V "sp|P08670|VIME_HUMAN,tr|B0YJC4|B0YJC4_HUMAN,tr|A0A1B0GTT5|A0A1B0GTT5_HUMAN" 3 877.4425 1.96 583 8676 2 877.442314 439.7285 Vimentin OS=Homo sapiens OX=9606 GN=VIM PE=1 SV=4 5.83 2295.5 - 311839 - - - -0.2336 - 1.344 0.362 - 125.9 1 2 0 -0.0002 7 0 0 0 2.69E+07 1.38E+07 - - - 2.6515 0.9998 221125_WJC_METTL3_EV_vs_WT_F01.08701.08701.2 5.78E-06 16-Aug K.DVNQQEFVR.A "sp|P39019|RS19_HUMAN,tr|M0R140|M0R140_HUMAN,tr|M0R2L9|M0R2L9_HUMAN,tr|M0QYF7|M0QYF7_HUMAN" 4 1133.5465 1.14 589 8701 2 1133.545911 567.7805 40S ribosomal protein S19 OS=Homo sapiens OX=9606 GN=RPS19 PE=1 SV=2 4.37 2299.5 - 120364 - - - -0.5514 - 1.689 0.528 - 265.5 1 2 0 -0.0006 9 0 0 0 5.28E+06 4.63E+06 - - - 4.457 0.9797 221125_WJC_METTL3_EV_vs_WT_F01.08711.08711.2 0.923 12-Jul K.VITTVLK[136.11].F "sp|Q13439|GOGA4_HUMAN,tr|H0Y6I0|H0Y6I0_HUMAN" 2 780.52 2.18 590 8711 2 780.519206 391.2673 Golgin subfamily A member 4 OS=Homo sapiens OX=9606 GN=GOLGA4 PE=1 SV=1 8.72 2301.3 - 358033 - - - -1.0698 - 1.133 0.115 - 148.5 1 2 0 -0.0008 7 0 0 0 3.40E+07 1.56E+07 - - - 0.2858 0.9933 221125_WJC_METTL3_EV_vs_WT_F01.08717.08717.2 0.399 14-Jun K.QLIVGVNK[136.11].M "sp|Q05639|EF1A2_HUMAN,sp|P68104|EF1A1_HUMAN,sp|Q5VTE0|EF1A3_HUMAN,sp|P06276|CHLE_HUMAN,tr|A0A2R8Y488|A0A2R8Y488_HUMAN,tr|A0A7I2V659|A0A7I2V659_HUMAN,tr|A0A7I2V3H3|A0A7I2V3H3_HUMAN,tr|F8WF14|F8WF14_HUMAN,tr|A0A2U3TZH3|A0A2U3TZH3_HUMAN,tr|A0A7I2V5N4|A0A7I2V5N4_HUMAN,tr|A0A087WVQ9|A0A087WVQ9_HUMAN,tr|A0A087WV01|A0A087WV01_HUMAN,tr|F8WEX7|F8WEX7_HUMAN" 13 877.5477 0.39 593 8717 2 877.547986 439.7811 Elongation factor 1-alpha 2 OS=Homo sapiens OX=9606 GN=EEF1A2 PE=1 SV=1 8.75 2302.1 - 245011 - - - 0.3806 - 1.268 0.159 - 106.5 1 2 0 0.0003 8 0 0 0 9.45E+06 2.44E+07 - - - 0.9314 0.7643 221125_WJC_METTL3_EV_vs_WT_F01.08760.08760.2 0.291 14-Jul R.PVGVVVPR[166.11].G "sp|O75525|KHDR3_HUMAN,tr|H0YAQ3|H0YAQ3_HUMAN,tr|E5RJZ9|E5RJZ9_HUMAN,tr|H0YAQ1|H0YAQ1_HUMAN" 4 831.5206 1.68 600 8760 2 831.520003 416.7676 "KH domain-containing, RNA-binding, signal transduction-associated protein 3 OS=Homo sapiens OX=9606 GN=KHDRBS3 PE=1 SV=1" 10.18 2309.3 - 197413 - - - -0.7095 - 1.162 0.223 - 112.3 1 1 0 -0.0006 8 0 0 0 1.73E+07 1.03E+07 - - - 1.1407 0.9989 221125_WJC_METTL3_EV_vs_WT_F01.08784.08784.2 0.00383 14-Jul K.VIPELNGK[136.11].L "sp|P04406|G3P_HUMAN,tr|E7EUT5|E7EUT5_HUMAN" 2 876.516 1.09 606 8784 2 876.515325 439.2653 Glyceraldehyde-3-phosphate dehydrogenase OS=Homo sapiens OX=9606 GN=GAPDH PE=1 SV=3 5.97 2313.2 - 215500 - - - -0.7906 - 1.504 0.281 - 166.5 1 2 0 -0.0007 8 0 0 0 4.99E+07 4.57E+07 - - - 2.3471 0.9986 221125_WJC_METTL3_EV_vs_WT_F01.08792.08792.2 0.00267 16-Jul R.QTVAVGVIK.N "sp|Q05639|EF1A2_HUMAN,sp|P68104|EF1A1_HUMAN,sp|Q5VTE0|EF1A3_HUMAN,tr|A0A7I2V659|A0A7I2V659_HUMAN,tr|A0A2U3TZH3|A0A2U3TZH3_HUMAN,tr|A0A087WVQ9|A0A087WVQ9_HUMAN" 6 913.5597 0.73 610 8792 2 913.557994 457.7871 Elongation factor 1-alpha 2 OS=Homo sapiens OX=9606 GN=EEF1A2 PE=1 SV=1 8.75 2314.3 - 570341 - - - -1.8313 - 1.536 0.32 - 229.6 1 2 0 -0.0017 9 0 0 0 2.09E+07 2.85E+07 - - - 2.6456 0.9943 221125_WJC_METTL3_EV_vs_WT_F01.08806.08806.2 0.0187 14-Jun K.VIPELNGK.L "sp|P04406|G3P_HUMAN,tr|E7EUT5|E7EUT5_HUMAN" 2 868.5018 1.09 614 8806 2 868.499845 435.2582 Glyceraldehyde-3-phosphate dehydrogenase OS=Homo sapiens OX=9606 GN=GAPDH PE=1 SV=3 5.97 2316.5 - 752746 - - - -2.2717 - 1.229 0.298 - 86.2 2 2 0 -0.002 8 0 0 0 4.99E+07 4.57E+07 - - - 1.7288 0.8272 221125_WJC_METTL3_EV_vs_WT_F01.08814.08814.2 2.93 12-May R.TWAEAAK[136.11].T "sp|Q76L83|ASXL2_HUMAN,tr|E7EWD6|E7EWD6_HUMAN" 2 783.4007 1.56 618 8814 2 783.402636 392.7076 Putative Polycomb group protein ASXL2 OS=Homo sapiens OX=9606 GN=ASXL2 PE=1 SV=1 5.66 2317.5 - 1.53E+06 - - - 2.53 - 1.013 0.05 - 156.6 1 2 0 0.002 7 0 0 0 1.56E+08 1.00E+08 - - - -0.5494 0.9378 221125_WJC_METTL3_EV_vs_WT_F01.08833.08833.3 0.309 Jul-40 K.NFYQEHPDLAR[166.11].R "sp|P17844|DDX5_HUMAN,tr|J3QR02|J3QR02_HUMAN,tr|X6RLV5|X6RLV5_HUMAN,tr|A0A7I2V507|A0A7I2V507_HUMAN,tr|J3KTA4|J3KTA4_HUMAN,tr|J3KTQ4|J3KTQ4_HUMAN,tr|A0A7I2V2S0|A0A7I2V2S0_HUMAN,tr|J3QRQ7|J3QRQ7_HUMAN" 8 1398.6556 2.03 624 8833 3 1398.653701 467.2258 Probable ATP-dependent RNA helicase DDX5 OS=Homo sapiens OX=9606 GN=DDX5 PE=1 SV=1 5.32 2320.3 - 92329.6 - - - -1.3456 - 1.31 0.136 - 74.6 1 2 0 -0.0019 11 0 0 0 5.79E+06 2.85E+06 - - - 0.8228 0.9976 221125_WJC_METTL3_EV_vs_WT_F01.08843.08843.3 0.00988 Jun-40 K.NFYQEHPDLAR.R "sp|P17844|DDX5_HUMAN,tr|J3QR02|J3QR02_HUMAN,tr|X6RLV5|X6RLV5_HUMAN,tr|A0A7I2V507|A0A7I2V507_HUMAN,tr|J3KTA4|J3KTA4_HUMAN,tr|J3KTQ4|J3KTQ4_HUMAN,tr|A0A7I2V2S0|A0A7I2V2S0_HUMAN,tr|J3QRQ7|J3QRQ7_HUMAN" 8 1388.6473 2.03 628 8843 3 1388.646349 463.8897 Probable ATP-dependent RNA helicase DDX5 OS=Homo sapiens OX=9606 GN=DDX5 PE=1 SV=1 5.32 2321.7 - 159542 - - - -0.6942 - 1.428 0.283 - 49.3 1 2 0 -0.001 11 0 0 0 5.79E+06 2.85E+06 - - - 2.707 0.9953 221125_WJC_METTL3_EV_vs_WT_F01.08860.08860.2 0.353 14-May R.NNFAVGYR.T "sp|P45880|VDAC2_HUMAN,tr|Q5JSD1|Q5JSD1_HUMAN,tr|Q5JSD2|Q5JSD2_HUMAN,tr|A0A0A0MR02|A0A0A0MR02_HUMAN" 4 939.4563 1.09 633 8860 2 939.456262 470.7354 Voltage-dependent anion-selective channel protein 2 OS=Homo sapiens OX=9606 GN=VDAC2 PE=1 SV=2 8.75 2324.2 - 74440 - - - -0.0032 - 1.093 0.249 - 68.1 1 2 0 0 8 0 0 0 2.15E+06 1.98E+06 - - - 1.1483 0.9977 221125_WJC_METTL3_EV_vs_WT_F01.08862.08862.2 0.311 14-Jul R.LVGDVIQR.F "sp|O00746|NDKM_HUMAN,tr|Q4TT34|Q4TT34_HUMAN,tr|A0A087WVT9|A0A087WVT9_HUMAN,tr|H0Y6J0|H0Y6J0_HUMAN,tr|F2Z2X0|F2Z2X0_HUMAN" 5 898.5236 2.41 635 8862 2 898.523201 450.2691 "Nucleoside diphosphate kinase, mitochondrial OS=Homo sapiens OX=9606 GN=NME4 PE=1 SV=1" 5.84 2324.5 - 379273 - - - -0.4619 - 1.288 0.255 - 142.9 1 2 0 -0.0004 8 0 0 0 3.15E+07 1.31E+07 - - - 1.6876 0.9306 221125_WJC_METTL3_EV_vs_WT_F01.08867.08867.2 3.13 12-Jun R.DLAENIR.K tr|A0A0C4DGZ7|A0A0C4DGZ7_HUMAN 1 829.4294 0.53 637 8867 2 829.429071 415.722 Ankyrin repeat and death domain-containing protein 1A OS=Homo sapiens OX=9606 GN=ANKDD1A PE=4 SV=1 4.37 2325.2 - 690480 - - - -0.3738 - 1.068 0.014 - 141.1 1 2 0 -0.0003 7 0 0 0 2.91E+07 5.45E+07 - - - -0.6472 0.8248 221125_WJC_METTL3_EV_vs_WT_F01.08933.08933.2 5.14 14-Jun K.IVTSLGLK[136.11].L "sp|Q7Z2Z2|EFL1_HUMAN,tr|A0A3B3ITU1|A0A3B3ITU1_HUMAN" 2 837.5415 1.02 649 8933 2 837.539817 419.778 Elongation factor-like GTPase 1 OS=Homo sapiens OX=9606 GN=EFL1 PE=1 SV=2 8.75 2336.1 - 200698 - - - -2.0142 - 1.018 0.041 - 61.9 3 2 0 -0.0017 8 0 0 0 1.22E+07 1.19E+07 - - - -0.816 0.9892 221125_WJC_METTL3_EV_vs_WT_F01.09052.09052.2 0.512 16-May K.VQFLEQQNK.V sp|P19013|K2C4_HUMAN 1 1132.5877 0.88 680 9052 2 1132.588516 567.3011 "Keratin, type II cytoskeletal 4 OS=Homo sapiens OX=9606 GN=KRT4 PE=1 SV=5" 5.97 2354.1 - 111214 - - - 0.7443 - 1.145 0.169 - 96.8 1 2 0 0.0008 9 0 0 0 3.79E+06 4.33E+06 - - - 0.6807 0.9312 221125_WJC_METTL3_EV_vs_WT_F01.09081.09081.2 7.33 14-May R.LLTGPVVR.G "sp|Q9P2D1|CHD7_HUMAN,sp|Q3L8U1|CHD9_HUMAN,tr|H3BTW3|H3BTW3_HUMAN,tr|A0A087WU44|A0A087WU44_HUMAN" 4 853.5385 1.23 685 9081 2 853.538597 427.7765 Chromodomain-helicase-DNA-binding protein 7 OS=Homo sapiens OX=9606 GN=CHD7 PE=1 SV=3 9.75 2358.9 - 212448 - - - 0.0691 - 1.073 0.032 - 68.7 2 2 0 0.0001 8 0 0 0 3.52E+07 2.86E+07 - - - -0.6446 0.9968 221125_WJC_METTL3_EV_vs_WT_F01.09091.09091.2 0.579 14-Jul R.LLTGPVVR[166.11].G "sp|Q9P2D1|CHD7_HUMAN,sp|Q3L8U1|CHD9_HUMAN,tr|H3BTW3|H3BTW3_HUMAN,tr|A0A087WU44|A0A087WU44_HUMAN" 4 863.5468 1.23 689 9091 2 863.545982 432.7807 Chromodomain-helicase-DNA-binding protein 7 OS=Homo sapiens OX=9606 GN=CHD7 PE=1 SV=3 9.75 2360.2 - 468558 - - - -0.9565 - 1.565 0.157 - 125 1 2 0 -0.0008 8 0 0 0 3.52E+07 2.86E+07 - - - 1.5511 0.9803 221125_WJC_METTL3_EV_vs_WT_F01.09105.09105.2 1.69 12-Jun K.LEPVPLK[136.11].G "sp|Q13045|FLII_HUMAN,tr|J3KS54|J3KS54_HUMAN" 2 802.5044 1.09 693 9105 2 802.50381 402.2595 Protein flightless-1 homolog OS=Homo sapiens OX=9606 GN=FLII PE=1 SV=2 6 2362.4 - 467192 - - - -0.724 - 1.196 0.083 - 156.9 1 2 0 -0.0006 7 0 0 0 1.73E+07 1.58E+07 - - - 0.221 0.9928 221125_WJC_METTL3_EV_vs_WT_F01.09114.09114.2 0.0105 18-Jul R.GYSFTTTAER[166.11].E "sp|P63261|ACTG_HUMAN,sp|P60709|ACTB_HUMAN,tr|A0A804GS07|A0A804GS07_HUMAN,tr|I3L3I0|I3L3I0_HUMAN,tr|E7EVS6|E7EVS6_HUMAN,tr|A0A6Q8PFE4|A0A6Q8PFE4_HUMAN,tr|I3L1U9|I3L1U9_HUMAN,tr|A0A2R8YEA7|A0A2R8YEA7_HUMAN,tr|A0A2R8Y793|A0A2R8Y793_HUMAN,tr|I3L4N8|I3L4N8_HUMAN" 10 1141.5279 1.16 696 9114 2 1141.524497 571.7712 "Actin, cytoplasmic 2 OS=Homo sapiens OX=9606 GN=ACTG1 PE=1 SV=1" 6 2363.7 - 165120 - - - -3.0012 - 1.187 0.331 - 89.2 1 2 0 -0.0034 10 0 0 0 1.03E+07 8.87E+06 - - - 1.9632 0.9997 221125_WJC_METTL3_EV_vs_WT_F01.09159.09159.2 0.00185 18-Oct K.FADLSEAANR.N "sp|P08670|VIME_HUMAN,tr|B0YJC5|B0YJC5_HUMAN,tr|B0YJC4|B0YJC4_HUMAN" 3 1092.52 1.66 705 9159 2 1092.518347 547.2673 Vimentin OS=Homo sapiens OX=9606 GN=VIM PE=1 SV=4 4.37 2371.1 - 155120 - - - -1.5011 - 1.785 0.457 - 322.2 1 2 0 -0.0016 10 0 0 0 1.97E+07 1.19E+07 - - - 4.0332 0.9998 221125_WJC_METTL3_EV_vs_WT_F01.09174.09174.3 0.0126 Sep-40 R.SLGTADVHFER[166.11].K "sp|Q86V81|THOC4_HUMAN,tr|E9PB61|E9PB61_HUMAN" 2 1240.6076 0.5 709 9174 3 1240.605333 414.5431 THO complex subunit 4 OS=Homo sapiens OX=9606 GN=ALYREF PE=1 SV=3 5.3 2373.4 - 147862 - - - -1.8031 - 2.015 0.419 - 98 1 2 0 -0.0022 11 0 0 0 3.39E+06 6.77E+06 - - - 5.2012 0.9998 221125_WJC_METTL3_EV_vs_WT_F01.09181.09181.2 0.00668 18-Sep K.YEELQVTAGR.H "sp|P48668|K2C6C_HUMAN,sp|O95678|K2C75_HUMAN,sp|P02538|K2C6A_HUMAN" 3 1164.5775 2.37 711 9181 2 1164.576994 583.296 "Keratin, type II cytoskeletal 6C OS=Homo sapiens OX=9606 GN=KRT6C PE=1 SV=3" 4.53 2374.4 - 165959 - - - -0.4362 - 1.873 0.422 - 342.1 1 2 0 -0.0005 10 0 0 0 8.13E+06 3.42E+06 - - - 3.9094 0.9977 221125_WJC_METTL3_EV_vs_WT_F01.09184.09184.2 0.0849 14-Jun K.ALVAYYQK[136.11].Y "sp|P62249|RS16_HUMAN,tr|M0R210|M0R210_HUMAN,tr|M0R3H0|M0R3H0_HUMAN,tr|M0QX76|M0QX76_HUMAN,tr|M0R1M5|M0R1M5_HUMAN" 5 962.5317 2.1 712 9184 2 962.530826 482.2731 40S ribosomal protein S16 OS=Homo sapiens OX=9606 GN=RPS16 PE=1 SV=2 8.54 2374.9 - 175603 - - - -0.8748 - 1.332 0.256 - 115.2 1 2 0 -0.0008 8 0 0 0 9.59E+06 4.57E+06 - - - 1.7962 0.9618 221125_WJC_METTL3_EV_vs_WT_F01.09215.09215.2 6.38 14-Jul K.GITLSVRP.- tr|A0A075B6Z2|A0A075B6Z2_HUMAN 1 841.5022 152.72 720 9215 2 841.501404 421.7584 T cell receptor alpha joining 56 (Fragment) OS=Homo sapiens OX=9606 GN=TRAJ56 PE=4 SV=1 9.75 2379.4 - 4.27E+06 - - - -0.8889 - 1.306 0.015 - 193.8 2 2 0 -0.0007 8 0 0 0 5.72E+08 3.74E+06 - - - -0.1777 0.9952 221125_WJC_METTL3_EV_vs_WT_F01.09216.09216.2 0.643 12-Jul K.LEATMLR.L "sp|Q12788|TBL3_HUMAN,tr|J3KNP2|J3KNP2_HUMAN" 2 832.4477 1.13 721 9216 2 832.447119 417.2311 Transducin beta-like protein 3 OS=Homo sapiens OX=9606 GN=TBL3 PE=1 SV=2 6 2379.6 - 460813 - - - -0.6667 - 1.436 0.134 - 149.1 1 2 0 -0.0006 7 0 0 0 2.58E+07 2.28E+07 - - - 1.1771 0.9737 221125_WJC_METTL3_EV_vs_WT_F01.09220.09220.2 5.28 12-Jun K.ILLSPER.V "sp|P24928|RPB1_HUMAN,tr|H3BVE3|H3BVE3_HUMAN,tr|A0A6Q8PGB0|A0A6Q8PGB0_HUMAN" 3 826.4913 1.33 722 9220 2 826.490465 414.2529 DNA-directed RNA polymerase II subunit RPB1 OS=Homo sapiens OX=9606 GN=POLR2A PE=1 SV=2 6 2380.2 - 266534 - - - -0.9534 - 1.202 0.062 - 117.2 1 2 0 -0.0008 7 0 0 0 4.22E+07 3.18E+07 - - - 0.0817 0.9349 221125_WJC_METTL3_EV_vs_WT_F01.09263.09263.2 2.77 12-Jul R.MIVGTLK.G "sp|O95777|LSM8_HUMAN,tr|C9JNV3|C9JNV3_HUMAN,tr|C9JIZ0|C9JIZ0_HUMAN,tr|F2Z2Y6|F2Z2Y6_HUMAN" 4 760.4517 2.37 731 9263 2 760.452088 381.2331 U6 snRNA-associated Sm-like protein LSm8 OS=Homo sapiens OX=9606 GN=LSM8 PE=1 SV=3 8.5 2387.2 - 699955 - - - 0.5142 - 1.105 0.012 - 203.4 1 2 0 0.0004 7 0 0 0 4.22E+08 1.78E+08 - - - -0.5541 0.9992 221125_WJC_METTL3_EV_vs_WT_F01.09275.09275.2 0.0366 16-Sep K.IVVVTAGVR[166.11].Q "sp|P07195|LDHB_HUMAN,tr|A8MW50|A8MW50_HUMAN,tr|A0A3B3IS95|A0A3B3IS95_HUMAN,tr|C9J7H8|C9J7H8_HUMAN,tr|F5H793|F5H793_HUMAN,tr|A0A5F9ZHM4|A0A5F9ZHM4_HUMAN" 6 922.5839 0.75 733 9275 2 922.583123 462.2992 L-lactate dehydrogenase B chain OS=Homo sapiens OX=9606 GN=LDHB PE=1 SV=2 9.75 2389.2 - 566942 - - - -0.866 - 1.803 0.27 - 307.7 1 2 0 -0.0008 9 0 0 0 1.19E+08 1.59E+08 - - - 2.7403 0.9995 221125_WJC_METTL3_EV_vs_WT_F01.09285.09285.2 0.00848 16-Sep K.IVVVTAGVR.Q "sp|P07195|LDHB_HUMAN,tr|A8MW50|A8MW50_HUMAN,tr|A0A3B3IS95|A0A3B3IS95_HUMAN,tr|C9J7H8|C9J7H8_HUMAN,tr|F5H793|F5H793_HUMAN,tr|A0A5F9ZHM4|A0A5F9ZHM4_HUMAN" 6 912.5757 0.75 736 9285 2 912.575067 457.2951 L-lactate dehydrogenase B chain OS=Homo sapiens OX=9606 GN=LDHB PE=1 SV=2 9.75 2390.7 - 770367 - - - -0.641 - 1.84 0.3 - 299.4 1 2 0 -0.0006 9 0 0 0 1.19E+08 1.59E+08 - - - 3.0207 0.9988 221125_WJC_METTL3_EV_vs_WT_F01.09299.09299.2 0.00133 16-Jun R.QLDNIVGER.G sp|P04259|K2C6B_HUMAN 1 1042.5407 2.66 741 9299 2 1042.538843 522.2776 "Keratin, type II cytoskeletal 6B OS=Homo sapiens OX=9606 GN=KRT6B PE=1 SV=5" 4.37 2392.6 - 113407 - - - -1.8033 - 1.439 0.367 - 186 1 2 0 -0.0019 9 0 0 0 8.63E+06 3.24E+06 - - - 2.804 0.992 221125_WJC_METTL3_EV_vs_WT_F01.09327.09327.2 0.0666 28-May K.AIADTGANVVVTGGK[136.11].V "sp|P50990|TCPQ_HUMAN,tr|H7C4C8|H7C4C8_HUMAN" 2 1379.75 0.29 749 9327 2 1379.752933 690.8823 T-complex protein 1 subunit theta OS=Homo sapiens OX=9606 GN=CCT8 PE=1 SV=4 5.88 2396.9 - 56069.6 - - - 2.1301 - 1.256 0.248 - 55 1 2 0 0.0029 15 0 0 0 6.84E+05 2.36E+06 - - - 1.4322 0.9692 221125_WJC_METTL3_EV_vs_WT_F01.09377.09377.2 1.07 22-Apr R.ALEESNYELEGK.L "sp|P13645|K1C10_HUMAN,tr|A0A1B0GVI3|A0A1B0GVI3_HUMAN" 2 1380.6409 105.21 760 9377 2 1380.639752 691.3277 "Keratin, type I cytoskeletal 10 OS=Homo sapiens OX=9606 GN=KRT10 PE=1 SV=6" 4.09 2404.7 - 36310.1 - - - -0.8243 - 0.945 0.143 - 39.3 1 2 0 -0.0011 12 0 0 0 3.13E+07 2.97E+05 - - - -0.052 0.9995 221125_WJC_METTL3_EV_vs_WT_F01.09436.09436.2 0.0746 12-Aug R.LMDVMAK.E sp|Q12874|SF3A3_HUMAN 1 806.403 5.33 776 9436 2 806.402691 404.2088 Splicing factor 3A subunit 3 OS=Homo sapiens OX=9606 GN=SF3A3 PE=1 SV=1 5.84 2413.6 - 458073 - - - -0.4229 - 1.467 0.385 - 217.9 1 2 0 -0.0003 7 0 0 0 2.27E+08 4.25E+07 - - - 3.0988 0.9241 221125_WJC_METTL3_EV_vs_WT_F01.09440.09440.2 0.733 12-Jun R.LMDVMAK[136.11].E sp|Q12874|SF3A3_HUMAN 1 814.4172 5.37 778 9440 2 814.415164 408.2159 Splicing factor 3A subunit 3 OS=Homo sapiens OX=9606 GN=SF3A3 PE=1 SV=1 5.84 2414.1 - 194438 - - - -2.5392 - 1.109 0.087 - 107.9 1 2 0 -0.0021 7 0 0 0 2.26E+08 4.21E+07 - - - 0.0107 0.9924 221125_WJC_METTL3_EV_vs_WT_F01.09454.09454.2 0.0701 12-Jul K.LGPEAFR.F sp|P33908|MA1A1_HUMAN 1 788.4181 1.52 784 9454 2 788.416619 395.2163 "Mannosyl-oligosaccharide 1,2-alpha-mannosidase IA OS=Homo sapiens OX=9606 GN=MAN1A1 PE=1 SV=3" 6 2416.1 - 306036 - - - -1.8632 - 1.307 0.189 - 152.8 1 2 0 -0.0015 7 0 0 0 2.86E+07 1.88E+07 - - - 1.2848 0.9682 221125_WJC_METTL3_EV_vs_WT_F01.09473.09473.2 0.0597 24-Apr K.ITESVAETAQTIK[136.11].K sp|Q96A49|SYAP1_HUMAN 1 1397.7493 1.26 789 9473 2 1397.747858 699.8819 Synapse-associated protein 1 OS=Homo sapiens OX=9606 GN=SYAP1 PE=1 SV=1 4.53 2419 - 59255.7 - - - -1.0495 - 0.975 0.173 - 24.1 4 2 0 -0.0015 13 0 0 0 4.04E+06 3.20E+06 - - - -0.0156 0.8773 221125_WJC_METTL3_EV_vs_WT_F01.09516.09516.2 1.67 24-Apr K.ITESVAETAQTIK.K sp|Q96A49|SYAP1_HUMAN 1 1389.7351 1.26 806 9516 2 1389.733614 695.8748 Synapse-associated protein 1 OS=Homo sapiens OX=9606 GN=SYAP1 PE=1 SV=1 4.53 2425.1 - 43709.8 - - - -1.0873 - 0.985 0.031 - 30.9 2 2 0 -0.0015 13 0 0 0 4.04E+06 3.20E+06 - - - -0.9038 0.998 221125_WJC_METTL3_EV_vs_WT_F01.09528.09528.2 0.226 20-Jul K.LVLVGDGGTGK.T "sp|P62826|RAN_HUMAN,tr|H0YFC6|H0YFC6_HUMAN,tr|B5MDF5|B5MDF5_HUMAN,tr|J3KQE5|J3KQE5_HUMAN,tr|F5H018|F5H018_HUMAN" 5 1014.571 1.34 808 9528 2 1014.570988 508.2928 GTP-binding nuclear protein Ran OS=Homo sapiens OX=9606 GN=RAN PE=1 SV=3 5.84 2427 - 136939 - - - 0.0276 - 1.449 0.238 - 106.4 1 2 0 0 11 0 0 0 8.64E+06 6.46E+06 - - - 1.8022 0.953 221125_WJC_METTL3_EV_vs_WT_F01.09541.09541.2 0.19 12-Jun K.LLNVGVR.E sp|O60512|B4GT3_HUMAN 1 769.481 1.15 810 9541 2 769.47859 385.7478 "Beta-1,4-galactosyltransferase 3 OS=Homo sapiens OX=9606 GN=B4GALT3 PE=1 SV=2" 9.75 2429.1 - 1.17E+06 - - - -3.1619 - 1.386 0.095 - 93.5 2 2 0 -0.0024 7 0 0 0 8.23E+07 7.13E+07 - - - 0.6417 0.927 221125_WJC_METTL3_EV_vs_WT_F01.09562.09562.2 1.23 14-Aug R.IIAEALTR[166.11].V "sp|Q969V3|NCLN_HUMAN,tr|K7EMW4|K7EMW4_HUMAN,tr|K7ELZ9|K7ELZ9_HUMAN,tr|K7ENM2|K7ENM2_HUMAN,tr|A0A0C4DGP7|A0A0C4DGP7_HUMAN" 5 895.5366 1.05 812 9562 2 895.532822 448.7756 Nicalin OS=Homo sapiens OX=9606 GN=NCLN PE=1 SV=2 6 2432.6 - 432505 - - - -4.26 - 1.405 0.109 - 179.7 1 2 0 -0.0038 8 0 0 0 3.75E+07 3.56E+07 - - - 0.8704 0.9989 221125_WJC_METTL3_EV_vs_WT_F01.09566.09566.2 0.000417 16-Sep R.QLDSIVGER.G "sp|P48668|K2C6C_HUMAN,sp|P13647|K2C5_HUMAN,sp|P02538|K2C6A_HUMAN,tr|F8W0C6|F8W0C6_HUMAN" 4 1015.5298 357.96 813 9566 2 1015.526778 508.7722 "Keratin, type II cytoskeletal 6C OS=Homo sapiens OX=9606 GN=KRT6C PE=1 SV=3" 4.37 2433.1 - 496529 - - - -2.9994 - 1.84 0.402 - 298.1 1 2 0 -0.003 9 0 0 0 3.39E+07 9.46E+04 - - - 3.7733 0.9463 221125_WJC_METTL3_EV_vs_WT_F01.09578.09578.2 0.627 14-Sep R.IIAEALTR.V "sp|Q969V3|NCLN_HUMAN,tr|K7EMW4|K7EMW4_HUMAN,tr|K7ELZ9|K7ELZ9_HUMAN,tr|K7ENM2|K7ENM2_HUMAN,tr|A0A0C4DGP7|A0A0C4DGP7_HUMAN" 5 885.5284 1.05 816 9578 2 885.525383 443.7715 Nicalin OS=Homo sapiens OX=9606 GN=NCLN PE=1 SV=2 6 2435 - 807739 - - - -3.3697 - 1.335 0.1 - 223 1 2 0 -0.003 8 0 0 0 3.75E+07 3.56E+07 - - - 0.6501 0.9083 221125_WJC_METTL3_EV_vs_WT_F01.09594.09594.2 4.49 12-Jun K.EGIVALR[166.11].R sp|P40227|TCPZ_HUMAN 1 766.4577 0.01 819 9594 2 766.455818 384.2361 T-complex protein 1 subunit zeta OS=Homo sapiens OX=9606 GN=CCT6A PE=1 SV=3 6.1 2437.4 - 500039 - - - -2.4007 - 1.228 0.035 - 166.7 2 2 0 -0.0018 7 0 0 0 7.13E+05 6.17E+07 - - - -0.1848 0.9884 221125_WJC_METTL3_EV_vs_WT_F01.09595.09595.2 0.209 14-Apr K.KPEVTPVK[136.11].V "sp|Q8WZ42|TITIN_HUMAN,tr|A0A0A0MTS7|A0A0A0MTS7_HUMAN" 2 904.5473 - 820 9595 2 904.545658 453.2809 Titin OS=Homo sapiens OX=9606 GN=TTN PE=1 SV=4 8.59 2437.6 - 69550.4 - - - -1.8352 - 1.058 0.238 - 54.8 1 2 0 -0.0017 8 0 0 0 - - - - - 0.9684 0.9647 221125_WJC_METTL3_EV_vs_WT_F01.09616.09616.2 3.32 12-May R.LYTVVPR.L "sp|P41252|SYIC_HUMAN,tr|A0A804HL54|A0A804HL54_HUMAN,tr|A0A804HIV9|A0A804HIV9_HUMAN,tr|A0A804HJN6|A0A804HJN6_HUMAN,tr|A0A804HHW9|A0A804HHW9_HUMAN,tr|A0A0A0MSX9|A0A0A0MSX9_HUMAN,tr|J3KR24|J3KR24_HUMAN,tr|A0A804HJ36|A0A804HJ36_HUMAN" 8 846.4963 0.79 828 9616 2 846.496846 424.2554 "Isoleucine--tRNA ligase, cytoplasmic OS=Homo sapiens OX=9606 GN=IARS1 PE=1 SV=2" 8.75 2440.6 - 150904 - - - 0.5989 - 1.053 0.118 - 82.1 3 2 0 0.0005 7 0 0 0 3.24E+07 4.08E+07 - - - -0.1371 0.9988 221125_WJC_METTL3_EV_vs_WT_F01.09629.09629.2 0.0121 12-Jul R.LYTVVPR[166.11].L "sp|P41252|SYIC_HUMAN,tr|A0A804HL54|A0A804HL54_HUMAN,tr|A0A804HIV9|A0A804HIV9_HUMAN,tr|A0A804HJN6|A0A804HJN6_HUMAN,tr|A0A804HHW9|A0A804HHW9_HUMAN,tr|A0A0A0MSX9|A0A0A0MSX9_HUMAN,tr|J3KR24|J3KR24_HUMAN,tr|A0A804HJ36|A0A804HJ36_HUMAN" 8 856.5046 0.78 833 9629 2 856.504734 429.2596 "Isoleucine--tRNA ligase, cytoplasmic OS=Homo sapiens OX=9606 GN=IARS1 PE=1 SV=2" 8.75 2442.4 - 586333 - - - 0.1459 - 1.403 0.286 - 219.9 1 2 0 0.0001 7 0 0 0 3.25E+07 4.16E+07 - - - 2.2263 0.7928 221125_WJC_METTL3_EV_vs_WT_F01.09639.09639.2 0.216 18-Jul R.VGATAAVYSA.A "sp|P0C0S5|H2AZ_HUMAN,sp|Q71UI9|H2AV_HUMAN,tr|E5RJU1|E5RJU1_HUMAN,tr|C9J0D1|C9J0D1_HUMAN,tr|A0A494C189|A0A494C189_HUMAN" 5 908.4603 - 838 9639 2 908.46043 455.2374 Histone H2A.Z OS=Homo sapiens OX=9606 GN=H2AZ1 PE=1 SV=2 5.49 2443.7 - 540347 - - - 0.0914 - 1.116 0.252 - 133.6 1 1 0 0.0001 10 0 0 0 - - - - - 1.2086 0.9944 221125_WJC_METTL3_EV_vs_WT_F01.09656.09656.2 0.146 12-Jul R.VLYSLAK.K "sp|P55265|DSRAD_HUMAN,tr|A0A3B3IRQ9|A0A3B3IRQ9_HUMAN,tr|A0A3B3ISU1|A0A3B3ISU1_HUMAN,tr|A0A7P0Z4K3|A0A7P0Z4K3_HUMAN,tr|A0A3B3ISX1|A0A3B3ISX1_HUMAN" 5 792.4745 1.01 842 9656 2 792.473723 397.2445 Double-stranded RNA-specific adenosine deaminase OS=Homo sapiens OX=9606 GN=ADAR PE=1 SV=4 8.56 2446.3 - 1.05E+06 - - - -1.0322 - 1.461 0.125 - 186.9 1 2 0 -0.0008 7 0 0 0 4.45E+07 4.40E+07 - - - 1.1653 0.9957 221125_WJC_METTL3_EV_vs_WT_F01.09665.09665.3 0.000819 Sep-48 R.NREEEWDPEYTPK.S "sp|Q9Y2W1|TR150_HUMAN,tr|A0A3B3ITZ9|A0A3B3ITZ9_HUMAN" 2 1691.7427 4.7 847 9665 3 1691.749036 564.9215 Thyroid hormone receptor-associated protein 3 OS=Homo sapiens OX=9606 GN=THRAP3 PE=1 SV=2 4.25 2447.4 - 92182.2 - - - 3.7275 - 1.714 0.436 - 119.6 1 2 1 0.0063 13 0 0 0 4.03E+06 8.58E+05 - - - 4.8601 0.9998 221125_WJC_METTL3_EV_vs_WT_F01.09666.09666.2 0.000456 22-Oct R.AQVQEFC[160.03]DYGTK[136.11].E "sp|Q86U44|MTA70_HUMAN,tr|H0YFV6|H0YFV6_HUMAN" 2 1452.6435 0 848 9666 2 1452.645351 727.329 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 4.37 2447.6 - 143502 - - - 1.288 - 2.236 0.506 - 192 1 2 0 0.0019 12 0 0 0 1.69E+05 4.79E+07 - - - 4.895 0.9983 221125_WJC_METTL3_EV_vs_WT_F01.09682.09682.2 1.31 14-Aug R.LLTGPVVR.G "sp|Q9P2D1|CHD7_HUMAN,sp|Q3L8U1|CHD9_HUMAN,tr|H3BTW3|H3BTW3_HUMAN,tr|A0A087WU44|A0A087WU44_HUMAN" 4 853.5385 1.18 856 9682 2 853.539193 427.7765 Chromodomain-helicase-DNA-binding protein 7 OS=Homo sapiens OX=9606 GN=CHD7 PE=1 SV=3 9.75 2449.7 - 964961 - - - 0.7674 - 1.536 0.237 - 181.7 1 2 0 0.0007 8 0 0 0 3.03E+08 2.57E+08 - - - 2.0857 0.9369 221125_WJC_METTL3_EV_vs_WT_F01.09735.09735.2 0.875 12-Jun R.VAPVLIR[166.11].E "sp|P30419|NMT1_HUMAN,sp|O60551|NMT2_HUMAN,tr|A0A7I2V3X4|A0A7I2V3X4_HUMAN,tr|A0A7I2V539|A0A7I2V539_HUMAN,tr|Q5VUC6|Q5VUC6_HUMAN,tr|A0A7I2V3U5|A0A7I2V3U5_HUMAN" 6 776.5148 0.33 869 9735 2 776.511575 389.2647 Glycylpeptide N-tetradecanoyltransferase 1 OS=Homo sapiens OX=9606 GN=NMT1 PE=1 SV=2 9.72 2458.1 - 1.29E+06 - - - -4.1261 - 1.089 0.217 - 140.3 1 2 0 -0.0032 7 0 0 0 2.41E+07 7.30E+07 - - - 0.9129 0.9694 221125_WJC_METTL3_EV_vs_WT_F01.09813.09813.2 0.068 16-Aug K.LSDGVAVLK[136.11].V "sp|P10809|CH60_HUMAN,tr|A0A7I2V2X6|A0A7I2V2X6_HUMAN,tr|A0A7I2YQK6|A0A7I2YQK6_HUMAN,tr|A0A7I2V599|A0A7I2V599_HUMAN" 4 908.5422 1.32 878 9813 2 908.536988 455.2784 "60 kDa heat shock protein, mitochondrial OS=Homo sapiens OX=9606 GN=HSPD1 PE=1 SV=2" 5.84 2470.8 - 712868 - - - -5.773 - 1.654 0.26 - 129.4 1 2 0 -0.0052 9 0 0 0 1.69E+08 1.28E+08 - - - 2.4155 0.9773 221125_WJC_METTL3_EV_vs_WT_F01.09825.09825.2 0.0808 16-Sep K.LSDGVAVLK.V "sp|P10809|CH60_HUMAN,tr|A0A7I2V2X6|A0A7I2V2X6_HUMAN,tr|A0A7I2YQK6|A0A7I2YQK6_HUMAN,tr|A0A7I2V599|A0A7I2V599_HUMAN" 4 900.528 1.32 881 9825 2 900.522592 451.2713 "60 kDa heat shock protein, mitochondrial OS=Homo sapiens OX=9606 GN=HSPD1 PE=1 SV=2" 5.84 2472.5 - 1.09E+06 - - - -6.042 - 1.604 0.334 - 174.2 1 2 0 -0.0054 9 0 0 0 1.69E+08 1.28E+08 - - - 2.8732 0.9462 221125_WJC_METTL3_EV_vs_WT_F01.09850.09850.2 2.48 12-Aug R.LLAALER[166.11].R sp|Q96A98|TIP39_HUMAN 1 794.489 1.15 883 9850 2 794.485473 398.2518 Tuberoinfundibular peptide of 39 residues OS=Homo sapiens OX=9606 GN=PTH2 PE=1 SV=1 6 2476.6 - 1.20E+07 - - - -4.3877 - 1.733 0.081 - 195.8 3 2 0 -0.0035 7 0 0 0 6.61E+08 5.76E+08 - - - 1.1673 0.9965 221125_WJC_METTL3_EV_vs_WT_F01.09865.09865.2 0.0021 12-Jun R.LVDMMER.G "sp|O00571|DDX3X_HUMAN,sp|O15523|DDX3Y_HUMAN,tr|A0A2R8YFR4|A0A2R8YFR4_HUMAN,tr|A0A2R8YCW1|A0A2R8YCW1_HUMAN,tr|A0A2R8YDH3|A0A2R8YDH3_HUMAN,tr|A0A2R8YDT5|A0A2R8YDT5_HUMAN,tr|A0A2R8Y645|A0A2R8Y645_HUMAN,tr|A0A2R8YF78|A0A2R8YF78_HUMAN,tr|A0A0D9SFB3|A0A0D9SFB3_HUMAN,tr|A0A2R8YFS5|A0A2R8YFS5_HUMAN,tr|A0A0D9SF53|A0A0D9SF53_HUMAN,tr|A0A2R8Y5G6|A0A2R8Y5G6_HUMAN,tr|A0A2R8Y7T2|A0A2R8Y7T2_HUMAN,tr|A0A0D9SG12|A0A0D9SG12_HUMAN,tr|F6S8Q4|F6S8Q4_HUMAN,tr|A0A2U3TZJ9|A0A2U3TZJ9_HUMAN,tr|A0A2R8Y4A4|A0A2R8Y4A4_HUMAN" 17 892.4147 1.2 884 9865 2 892.411191 447.2146 ATP-dependent RNA helicase DDX3X OS=Homo sapiens OX=9606 GN=DDX3X PE=1 SV=3 4.37 2479.1 - 1.31E+06 - - - -3.8861 - 1.185 0.494 - 118.4 1 2 0 -0.0035 7 0 0 0 2.47E+08 2.06E+08 - - - 3.2264 0.9994 221125_WJC_METTL3_EV_vs_WT_F01.09871.09871.2 0.00294 12-Jul R.LVDMMER[166.11].G "sp|O00571|DDX3X_HUMAN,sp|O15523|DDX3Y_HUMAN,tr|A0A2R8YFR4|A0A2R8YFR4_HUMAN,tr|A0A2R8YCW1|A0A2R8YCW1_HUMAN,tr|A0A2R8YDH3|A0A2R8YDH3_HUMAN,tr|A0A2R8YDT5|A0A2R8YDT5_HUMAN,tr|A0A2R8Y645|A0A2R8Y645_HUMAN,tr|A0A2R8YF78|A0A2R8YF78_HUMAN,tr|A0A0D9SFB3|A0A0D9SFB3_HUMAN,tr|A0A2R8YFS5|A0A2R8YFS5_HUMAN,tr|A0A0D9SF53|A0A0D9SF53_HUMAN,tr|A0A2R8Y5G6|A0A2R8Y5G6_HUMAN,tr|A0A2R8Y7T2|A0A2R8Y7T2_HUMAN,tr|A0A0D9SG12|A0A0D9SG12_HUMAN,tr|F6S8Q4|F6S8Q4_HUMAN,tr|A0A2U3TZJ9|A0A2U3TZJ9_HUMAN,tr|A0A2R8Y4A4|A0A2R8Y4A4_HUMAN" 17 902.4229 1.2 886 9871 2 902.423602 452.2187 ATP-dependent RNA helicase DDX3X OS=Homo sapiens OX=9606 GN=DDX3X PE=1 SV=3 4.37 2479.8 - 2.04E+06 - - - 0.7458 - 1.207 0.446 - 127 1 2 0 0.0007 7 0 0 0 2.47E+08 2.06E+08 - - - 2.9311 0.9441 221125_WJC_METTL3_EV_vs_WT_F01.09910.09910.2 0.0118 14-Jul K.PSPLLVGR.E "sp|Q13283|G3BP1_HUMAN,sp|Q9UN86|G3BP2_HUMAN,tr|A0A7I2V3E2|A0A7I2V3E2_HUMAN,tr|A0A7I2V5M7|A0A7I2V5M7_HUMAN,tr|A0A7I2V2R0|A0A7I2V2R0_HUMAN,tr|E5RH00|E5RH00_HUMAN,tr|E5RH42|E5RH42_HUMAN,tr|A0A7I2V4Y8|A0A7I2V4Y8_HUMAN,tr|D6RAC7|D6RAC7_HUMAN,tr|D6RGJ4|D6RGJ4_HUMAN,tr|A0A7I2V3C4|A0A7I2V3C4_HUMAN,tr|A0A7P0P2U7|A0A7P0P2U7_HUMAN,tr|A0A7I2V2S5|A0A7I2V2S5_HUMAN,tr|D6RB17|D6RB17_HUMAN,tr|A0A7I2YQU8|A0A7I2YQU8_HUMAN,tr|E5RJU8|E5RJU8_HUMAN,tr|A0A7I2YQS2|A0A7I2YQS2_HUMAN,tr|A0A7I2YQD9|A0A7I2YQD9_HUMAN,tr|D6R9A4|D6R9A4_HUMAN,tr|A0A7I2V651|A0A7I2V651_HUMAN,tr|E5RIF8|E5RIF8_HUMAN,tr|E5RI46|E5RI46_HUMAN,tr|A0A7I2YQN9|A0A7I2YQN9_HUMAN,tr|D6RBR0|D6RBR0_HUMAN,tr|D6RBW8|D6RBW8_HUMAN" 25 837.5072 1.29 890 9910 2 837.50569 419.7609 Ras GTPase-activating protein-binding protein 1 OS=Homo sapiens OX=9606 GN=G3BP1 PE=1 SV=1 10.18 2486.2 - 799574 - - - -1.8483 - 1.645 0.334 - 197.7 1 1 0 -0.0015 8 0 0 0 1.77E+08 1.38E+08 - - - 3.0086 0.9955 221125_WJC_METTL3_EV_vs_WT_F01.09930.09930.2 0.0569 12-Jun K.IQDWYDK.K sp|P35527|K1C9_HUMAN 1 966.4447 116.75 893 9930 2 966.441557 484.2296 "Keratin, type I cytoskeletal 9 OS=Homo sapiens OX=9606 GN=KRT9 PE=1 SV=3" 4.21 2489.3 - 244550 - - - -3.249 - 1.292 0.362 - 78.3 1 2 0 -0.0031 7 0 0 0 8.17E+06 7.00E+04 - - - 2.5255 0.9672 221125_WJC_METTL3_EV_vs_WT_F01.09932.09932.2 0.301 12-Jul K.FIGELGK.L "sp|P78344|IF4G2_HUMAN,tr|H0YEC5|H0YEC5_HUMAN,tr|H0Y3P2|H0Y3P2_HUMAN,tr|H0YCH5|H0YCH5_HUMAN,tr|H0YD77|H0YD77_HUMAN,tr|D3DQV9|D3DQV9_HUMAN" 6 762.4276 2.05 894 9932 2 762.425133 382.2211 Eukaryotic translation initiation factor 4 gamma 2 OS=Homo sapiens OX=9606 GN=EIF4G2 PE=1 SV=1 6 2489.5 - 974860 - - - -3.2226 - 1.288 0.147 - 166.2 1 2 0 -0.0025 7 0 0 0 1.08E+08 5.25E+07 - - - 0.9279 0.8124 221125_WJC_METTL3_EV_vs_WT_F01.09934.09934.2 0.0943 12-Jun K.FIGELGK[136.11].L "sp|P78344|IF4G2_HUMAN,tr|H0YEC5|H0YEC5_HUMAN,tr|H0Y3P2|H0Y3P2_HUMAN,tr|H0YCH5|H0YCH5_HUMAN,tr|H0YD77|H0YD77_HUMAN,tr|D3DQV9|D3DQV9_HUMAN" 6 770.4418 2.29 895 9934 2 770.437927 386.2282 Eukaryotic translation initiation factor 4 gamma 2 OS=Homo sapiens OX=9606 GN=EIF4G2 PE=1 SV=1 6 2489.7 - 657144 - - - -5.014 - 1.29 0.09 - 134.2 1 2 0 -0.0039 7 0 0 0 1.22E+08 5.31E+07 - - - 0.5114 0.9975 221125_WJC_METTL3_EV_vs_WT_F01.09954.09954.2 0.0176 26-Jun K.VQALEEANNDLENK.L sp|P35527|K1C9_HUMAN 1 1585.7584 999 902 9954 2 1585.753347 793.8865 "Keratin, type I cytoskeletal 9 OS=Homo sapiens OX=9606 GN=KRT9 PE=1 SV=3" 4 2492.7 - 105281 - - - -3.1739 - 1.335 0.442 - 103.6 1 2 0 -0.005 14 0 0 0 1.96E+06 0.00E+00 - - - 3.0291 0.9982 221125_WJC_METTL3_EV_vs_WT_F01.09959.09959.2 0.0122 14-Sep R.LGPLQVAR.V sp|P38117|ETFB_HUMAN 1 852.5181 1.67 905 9959 2 852.516068 427.2663 Electron transfer flavoprotein subunit beta OS=Homo sapiens OX=9606 GN=ETFB PE=1 SV=3 9.75 2493.3 - 509215 - - - -2.4269 - 1.709 0.295 - 256.5 1 2 0 -0.0021 8 0 0 0 7.09E+07 4.25E+07 - - - 2.8355 0.9987 221125_WJC_METTL3_EV_vs_WT_F01.09960.09960.2 0.0954 14-Aug R.VVLLAEGR[166.11].L sp|O43865|SAHH2_HUMAN 1 865.5261 0.65 906 9960 2 865.524149 433.7703 S-adenosylhomocysteine hydrolase-like protein 1 OS=Homo sapiens OX=9606 GN=AHCYL1 PE=1 SV=2 5.97 2493.4 - 500208 - - - -2.2218 - 1.56 0.357 - 338.1 1 2 0 -0.0019 8 0 0 0 1.62E+07 2.49E+07 - - - 3.0184 0.978 221125_WJC_METTL3_EV_vs_WT_F01.09988.09988.2 0.737 14-May K.GFVVINQK[136.11].G "sp|Q92526|TCPW_HUMAN,sp|P40227|TCPZ_HUMAN" 2 911.532 0.35 913 9988 2 911.53046 456.7733 T-complex protein 1 subunit zeta-2 OS=Homo sapiens OX=9606 GN=CCT6B PE=1 SV=5 8.75 2497.6 - 72103.1 - - - -1.6917 - 1.129 0.179 - 76.9 4 2 0 -0.0015 8 0 0 0 6.27E+05 1.79E+06 - - - 0.4596 0.9036 221125_WJC_METTL3_EV_vs_WT_F01.10000.10000.2 0.676 12-May R.ILADNPR.Y "sp|P42126|ECI1_HUMAN,tr|H3BS70|H3BS70_HUMAN,tr|Q96DC0|Q96DC0_HUMAN" 3 797.4396 11.4 918 10000 2 797.44296 399.7271 "Enoyl-CoA delta isomerase 1, mitochondrial OS=Homo sapiens OX=9606 GN=ECI1 PE=1 SV=1" 5.84 2499.3 - 265608 - - - 4.2737 - 1.093 0.185 - 66.9 1 2 0 0.0034 7 0 0 0 2.09E+07 1.83E+06 - - - 0.6881 0.9845 221125_WJC_METTL3_EV_vs_WT_F01.10002.10002.2 0.419 12-Jun K.GDVQTIR.W sp|Q702N8|XIRP1_HUMAN 1 787.4188 2992.73 919 10002 2 787.418123 394.7167 Xin actin-binding repeat-containing protein 1 OS=Homo sapiens OX=9606 GN=XIRP1 PE=1 SV=1 5.84 2499.5 - 464136 - - - -0.8814 - 1.276 0.081 - 175.9 1 2 0 -0.0007 7 0 0 0 1.24E+09 4.14E+05 - - - 0.4113 0.9968 221125_WJC_METTL3_EV_vs_WT_F01.10016.10016.2 0.392 12-Jul K.LVVALSR[166.11].T "sp|Q9BPX3|CND3_HUMAN,tr|D6RA93|D6RA93_HUMAN" 2 766.494 0.33 926 10016 2 766.493958 384.2543 Condensin complex subunit 3 OS=Homo sapiens OX=9606 GN=NCAPG PE=1 SV=1 9.75 2501.5 - 718118 - - - -0.1122 - 1.501 0.147 - 181.5 1 2 0 -0.0001 7 0 0 0 3.19E+07 9.55E+07 - - - 1.4136 0.9675 221125_WJC_METTL3_EV_vs_WT_F01.10024.10024.2 0.181 12-Jun K.AIFAGYK[136.11].R "sp|P18077|RL35A_HUMAN,tr|F8WB72|F8WB72_HUMAN,tr|C9K025|C9K025_HUMAN,tr|F8WBS5|F8WBS5_HUMAN" 4 776.4312 0.32 931 10024 2 776.434253 389.2229 60S ribosomal protein L35a OS=Homo sapiens OX=9606 GN=RPL35A PE=1 SV=2 8.63 2502.6 - 190835 - - - 3.8986 - 1.319 0.188 - 116.3 1 2 0 0.003 7 0 0 0 1.02E+07 3.22E+07 - - - 1.3059 0.9973 221125_WJC_METTL3_EV_vs_WT_F01.10091.10091.2 0.0408 12-Jun R.FLAPYGR.Q "sp|Q8N3Z3|GTPB8_HUMAN,tr|F8WBY6|F8WBY6_HUMAN,tr|A0A087WUP3|A0A087WUP3_HUMAN" 3 822.4388 0.56 951 10091 2 822.437306 412.2267 GTP-binding protein 8 OS=Homo sapiens OX=9606 GN=GTPBP8 PE=1 SV=1 8.75 2512.5 - 1.19E+06 - - - -1.8457 - 1.299 0.3 - 146.2 1 2 0 -0.0015 7 0 0 0 6.30E+07 1.13E+08 - - - 2.0852 0.9827 221125_WJC_METTL3_EV_vs_WT_F01.10099.10099.2 0.00434 12-Jul R.VVDLMAH.M "sp|P04406|G3P_HUMAN,tr|E7EUT5|E7EUT5_HUMAN" 2 783.3949 - 954 10099 2 783.393406 392.7047 Glyceraldehyde-3-phosphate dehydrogenase OS=Homo sapiens OX=9606 GN=GAPDH PE=1 SV=3 5.08 2513.6 - 1.54E+07 - - - -1.9198 - 1.583 0.551 - 187.1 1 1 0 -0.0015 7 0 0 0 - - - - - 4.5656 0.9842 221125_WJC_METTL3_EV_vs_WT_F01.10100.10100.2 2.11 12-Jun R.VLISSLK.D "sp|Q8N684|CPSF7_HUMAN,sp|Q8NH83|OR4A5_HUMAN,tr|F5H669|F5H669_HUMAN" 3 758.4902 0.73 955 10100 2 758.488775 380.2524 Cleavage and polyadenylation specificity factor subunit 7 OS=Homo sapiens OX=9606 GN=CPSF7 PE=1 SV=1 8.72 2513.8 - 840329 - - - -1.8669 - 1.41 0.086 - 135.4 1 2 0 -0.0014 7 0 0 0 3.61E+07 4.97E+07 - - - 0.7644 0.9195 221125_WJC_METTL3_EV_vs_WT_F01.10104.10104.2 9.52 14-Apr K.TDTGC[160.03]PAR.L tr|D6RC99|D6RC99_HUMAN 1 876.376 1.71 957 10104 2 876.374945 439.1953 Guanylate cyclase OS=Homo sapiens OX=9606 GN=GUCY1B1 PE=1 SV=1 5.5 2514.3 - 151332 - - - -1.165 - 0.752 0.166 - 64.5 1 2 0 -0.001 8 0 0 0 1.87E+07 1.09E+07 - - - -0.5928 0.9006 221125_WJC_METTL3_EV_vs_WT_F01.10116.10116.2 0.0023 14-Jun K.MAPTVLVH.S "sp|Q6W2J9|BCOR_HUMAN,tr|H7BZ37|H7BZ37_HUMAN,tr|H7C2V9|H7C2V9_HUMAN,tr|H7BYY2|H7BYY2_HUMAN,tr|H7C231|H7C231_HUMAN" 5 866.4684 - 964 10116 2 866.466067 434.2415 BCL-6 corepressor OS=Homo sapiens OX=9606 GN=BCOR PE=1 SV=1 6.49 2515.8 - 334325 - - - -2.7029 - 1.363 0.41 - 159 1 1 0 -0.0023 8 0 0 0 - - - - - 3.0025 0.9894 221125_WJC_METTL3_EV_vs_WT_F01.10124.10124.2 2.25 12-Jul R.IVEGILK.R "sp|Q15370|ELOB_HUMAN,tr|I3L0M9|I3L0M9_HUMAN,tr|A0A0B4J296|A0A0B4J296_HUMAN,tr|B8ZZU8|B8ZZU8_HUMAN" 4 770.4902 0.97 967 10124 2 770.488426 386.2524 Elongin-B OS=Homo sapiens OX=9606 GN=ELOB PE=1 SV=1 6 2516.8 - 692278 - - - -2.2907 - 1.449 0.142 - 105.8 1 2 0 -0.0018 7 0 0 0 4.23E+08 4.35E+08 - - - 1.2644 0.98 221125_WJC_METTL3_EV_vs_WT_F01.10128.10128.2 1.84 14-Jun K.LLEATELK[136.11].G "sp|Q13813|SPTN1_HUMAN,tr|A0A0D9SF54|A0A0D9SF54_HUMAN,tr|A0A0D9SGF6|A0A0D9SGF6_HUMAN" 3 923.5419 1.65 968 10128 2 923.540057 462.7782 "Spectrin alpha chain, non-erythrocytic 1 OS=Homo sapiens OX=9606 GN=SPTAN1 PE=1 SV=3" 4.53 2517.4 - 436902 - - - -1.9934 - 1.244 0.13 - 87 1 2 0 -0.0018 8 0 0 0 2.28E+07 1.38E+07 - - - 0.6591 0.994 221125_WJC_METTL3_EV_vs_WT_F01.10140.10140.2 0.164 14-Jul K.YVPLADVK.S "sp|P42167|LAP2B_HUMAN,tr|G5E972|G5E972_HUMAN,tr|H0YJH7|H0YJH7_HUMAN" 3 903.5066 1.49 972 10140 2 903.504702 452.7606 "Lamina-associated polypeptide 2, isoforms beta\gamma OS=Homo sapiens OX=9606 GN=TMPO PE=1 SV=2" 5.83 2519.1 - 608642 - - - -2.0664 - 1.258 0.248 - 168.3 1 2 0 -0.0019 8 0 0 0 3.53E+07 2.37E+07 - - - 1.5644 0.996 221125_WJC_METTL3_EV_vs_WT_F01.10177.10177.2 1.39 12-Jul K.LTGMAFR[166.11].V "sp|O14556|G3PT_HUMAN,sp|P04406|G3P_HUMAN,tr|E7EUT5|E7EUT5_HUMAN" 3 804.4192 0.91 983 10177 2 804.41771 403.2169 "Glyceraldehyde-3-phosphate dehydrogenase, testis-specific OS=Homo sapiens OX=9606 GN=GAPDHS PE=1 SV=2" 9.75 2524.5 - 1.23E+06 - - - -1.8075 - 1.668 0.148 - 147.6 1 2 0 -0.0015 7 0 0 0 9.14E+09 1.00E+10 - - - 1.7548 0.9967 221125_WJC_METTL3_EV_vs_WT_F01.10182.10182.2 0.557 12-Jul R.MGLVMDR[166.11].M "sp|P52272|HNRPM_HUMAN,tr|A0A087X0X3|A0A087X0X3_HUMAN,tr|M0QZM1|M0QZM1_HUMAN" 3 830.4018 1.22 985 10182 2 830.39977 416.2082 Heterogeneous nuclear ribonucleoprotein M OS=Homo sapiens OX=9606 GN=HNRNPM PE=1 SV=3 5.59 2525.2 - 347995 - - - -2.4446 - 1.603 0.237 - 197.8 1 2 0 -0.002 7 0 0 0 1.77E+09 1.45E+09 - - - 2.286 0.9994 221125_WJC_METTL3_EV_vs_WT_F01.10188.10188.2 0.0651 12-Aug K.LTGMAFR.V "sp|O14556|G3PT_HUMAN,sp|P04406|G3P_HUMAN,tr|E7EUT5|E7EUT5_HUMAN" 3 794.4109 0.91 988 10188 2 794.409851 398.2127 "Glyceraldehyde-3-phosphate dehydrogenase, testis-specific OS=Homo sapiens OX=9606 GN=GAPDHS PE=1 SV=2" 9.75 2526 - 1.91E+06 - - - -1.3129 - 1.822 0.303 - 201.9 1 2 0 -0.001 7 0 0 0 9.14E+09 1.00E+10 - - - 3.1796 0.992 221125_WJC_METTL3_EV_vs_WT_F01.10192.10192.2 0.058 12-Jul R.MGLVMDR.M "sp|P52272|HNRPM_HUMAN,tr|A0A087X0X3|A0A087X0X3_HUMAN,tr|M0QZM1|M0QZM1_HUMAN" 3 820.3935 1.26 989 10192 2 820.389743 411.204 Heterogeneous nuclear ribonucleoprotein M OS=Homo sapiens OX=9606 GN=HNRNPM PE=1 SV=3 5.59 2526.6 - 941327 - - - -4.6161 - 1.682 0.303 - 228.3 1 2 0 -0.0038 7 0 0 0 1.77E+09 1.40E+09 - - - 2.9254 0.9771 221125_WJC_METTL3_EV_vs_WT_F01.10201.10201.2 1.46 16-Apr R.VLMGGTLGR.S sp|Q9H6T0|ESRP2_HUMAN 1 902.5008 1.48 996 10201 2 902.49988 452.2577 Epithelial splicing regulatory protein 2 OS=Homo sapiens OX=9606 GN=ESRP2 PE=1 SV=1 9.72 2527.8 - 152613 - - - -0.9884 - 0.888 0.201 - 57.9 1 2 0 -0.0009 9 0 0 0 1.94E+07 1.31E+07 - - - 0.1817 0.9536 221125_WJC_METTL3_EV_vs_WT_F01.10243.10243.2 11.9 12-Jul R.LIITQVR.R "sp|P42704|LPPRC_HUMAN,tr|A0A804HI14|A0A804HI14_HUMAN,tr|A0A804HL40|A0A804HL40_HUMAN,tr|A0A804HKJ0|A0A804HKJ0_HUMAN,tr|A0A804HKR3|A0A804HKR3_HUMAN,tr|A0A804HIN4|A0A804HIN4_HUMAN,tr|A0A804HLG8|A0A804HLG8_HUMAN,tr|A0A804HJA1|A0A804HJA1_HUMAN,tr|A0A804HHY9|A0A804HHY9_HUMAN,tr|A0A804HI40|A0A804HI40_HUMAN,tr|A0A804HJZ1|A0A804HJZ1_HUMAN,tr|A0A804HIQ7|A0A804HIQ7_HUMAN,tr|A0A804HK30|A0A804HK30_HUMAN,tr|A0A804HKI2|A0A804HKI2_HUMAN,tr|A0A804HJI0|A0A804HJI0_HUMAN,tr|A0A804HKX6|A0A804HKX6_HUMAN,tr|A0A804HKK7|A0A804HKK7_HUMAN,tr|A0A804HIG4|A0A804HIG4_HUMAN" 18 841.5385 0.72 1008 10243 2 841.53517 421.7765 "Leucine-rich PPR motif-containing protein, mitochondrial OS=Homo sapiens OX=9606 GN=LRPPRC PE=1 SV=3" 9.75 2534 - 5.74E+06 - - - -4.0022 - 1.35 0.147 - 185.4 1 2 0 -0.0034 7 0 0 0 2.08E+08 2.91E+08 - - - 1.0766 0.9967 221125_WJC_METTL3_EV_vs_WT_F01.10260.10260.2 0.00252 16-Aug R.QEYEQLIAK.N "sp|P35527|K1C9_HUMAN,tr|K7EQQ3|K7EQQ3_HUMAN" 2 1120.5764 27.41 1015 10260 2 1120.572118 561.2955 "Keratin, type I cytoskeletal 9 OS=Homo sapiens OX=9606 GN=KRT9 PE=1 SV=3" 4.53 2536.3 - 212752 - - - -3.8569 - 1.573 0.396 - 221.7 1 2 0 -0.0043 9 0 0 0 2.45E+07 8.96E+05 - - - 3.275 0.9879 221125_WJC_METTL3_EV_vs_WT_F01.10276.10276.2 0.99 12-Jun R.VFASPLR.L sp|Q9UK33|ZN580_HUMAN 1 788.4545 1.71 1022 10276 2 788.452422 395.2345 Zinc finger protein 580 OS=Homo sapiens OX=9606 GN=ZNF580 PE=1 SV=1 9.72 2538.5 - 881115 - - - -2.6026 - 1.203 0.231 - 94.4 1 2 0 -0.0021 7 0 0 0 5.94E+07 3.48E+07 - - - 1.3321 0.9983 221125_WJC_METTL3_EV_vs_WT_F01.10294.10294.2 0.0599 18-Jul R.IITEGFEAAK[136.11].E sp|P40227|TCPZ_HUMAN 1 1085.5848 0.44 1027 10294 2 1085.582672 543.7997 T-complex protein 1 subunit zeta OS=Homo sapiens OX=9606 GN=CCT6A PE=1 SV=3 4.53 2541 - 175587 - - - -1.9842 - 1.543 0.317 - 97.3 1 2 0 -0.0022 10 0 0 0 5.47E+06 1.25E+07 - - - 2.5924 0.9819 221125_WJC_METTL3_EV_vs_WT_F01.10303.10303.2 2.08 12-Jun K.VLPTIPK[136.11].E "sp|P35606|COPB2_HUMAN,sp|Q8ND07|BBOF1_HUMAN,tr|H0Y938|H0Y938_HUMAN,tr|A0A7I2V258|A0A7I2V258_HUMAN,tr|H0YAC7|H0YAC7_HUMAN" 5 774.5095 0.76 1031 10303 2 774.507953 388.262 Coatomer subunit beta' OS=Homo sapiens OX=9606 GN=COPB2 PE=1 SV=2 8.72 2542.1 - 287004 - - - -1.9664 - 1.237 0.136 - 99.3 1 2 0 -0.0015 7 0 0 0 1.75E+07 2.29E+07 - - - 0.7189 0.9593 221125_WJC_METTL3_EV_vs_WT_F01.10315.10315.2 1.39 16-Jun K.SPLQSVVVR.R "sp|Q9Y2W1|TR150_HUMAN,tr|A0A3B3ITZ9|A0A3B3ITZ9_HUMAN" 2 983.5764 2.57 1036 10315 2 983.574149 492.7955 Thyroid hormone receptor-associated protein 3 OS=Homo sapiens OX=9606 GN=THRAP3 PE=1 SV=2 9.47 2543.7 - 145816 - - - -2.2683 - 1.225 0.092 - 154.1 1 2 0 -0.0022 9 0 0 0 3.23E+07 1.26E+07 - - - 0.3069 0.9555 221125_WJC_METTL3_EV_vs_WT_F01.10321.10321.2 0.417 14-Jun R.AVAEMVLK[136.11].G sp|Q96CU9|FXRD1_HUMAN 1 867.4979 25.13 1038 10321 2 867.495531 434.7562 FAD-dependent oxidoreductase domain-containing protein 1 OS=Homo sapiens OX=9606 GN=FOXRED1 PE=1 SV=2 6.05 2544.7 - 215306 - - - -2.7597 - 1.028 0.184 - 77 1 2 0 -0.0024 8 0 0 0 1.75E+08 6.95E+06 - - - 0.4826 0.9924 221125_WJC_METTL3_EV_vs_WT_F01.10343.10343.2 0.0723 16-Apr R.LLPLAANGR[166.11].L "sp|Q6P1X6|CH082_HUMAN,tr|H0YF29|H0YF29_HUMAN" 2 933.5635 0.4 1048 10343 2 933.563877 467.789 UPF0598 protein C8orf82 OS=Homo sapiens OX=9606 GN=C8orf82 PE=1 SV=2 9.75 2547.7 - 94514.1 - - - 0.3824 - 0.991 0.248 - 45 1 2 0 0.0004 9 0 0 0 1.67E+06 4.19E+06 - - - 0.8465 0.9992 221125_WJC_METTL3_EV_vs_WT_F01.10345.10345.2 0.0546 16-Jun K.SPLQSVVVR[166.11].R "sp|Q9Y2W1|TR150_HUMAN,tr|A0A3B3ITZ9|A0A3B3ITZ9_HUMAN" 2 993.5847 2.57 1049 10345 2 993.584295 497.7996 Thyroid hormone receptor-associated protein 3 OS=Homo sapiens OX=9606 GN=THRAP3 PE=1 SV=2 9.47 2547.9 - 177029 - - - -0.3573 - 1.499 0.314 - 124.8 1 2 0 -0.0004 9 0 0 0 3.23E+07 1.26E+07 - - - 2.5312 0.9728 221125_WJC_METTL3_EV_vs_WT_F01.10351.10351.2 1.54 12-May K.AC[160.03]TILLR[166.11].G "sp|P49368|TCPG_HUMAN,tr|B4DUR8|B4DUR8_HUMAN" 2 855.4876 2.62 1051 10351 2 855.485864 428.7511 T-complex protein 1 subunit gamma OS=Homo sapiens OX=9606 GN=CCT3 PE=1 SV=4 8.29 2548.7 - 373945 - - - -2.0047 - 1.227 0.146 - 97.9 5 2 0 -0.0017 7 0 0 0 4.47E+07 1.71E+07 - - - 0.4548 0.9991 221125_WJC_METTL3_EV_vs_WT_F01.10361.10361.2 0.25 12-Aug R.LNELLVK.A "sp|Q12931|TRAP1_HUMAN,tr|I3L0K7|I3L0K7_HUMAN,tr|I3L253|I3L253_HUMAN" 3 827.5117 1.72 1055 10361 2 827.511688 414.7631 "Heat shock protein 75 kDa, mitochondrial OS=Homo sapiens OX=9606 GN=TRAP1 PE=1 SV=3" 6 2550 - 1.64E+06 - - - 0.0411 - 1.791 0.219 - 201.6 1 2 0 0 7 0 0 0 4.36E+08 2.54E+08 - - - 2.5051 0.9994 221125_WJC_METTL3_EV_vs_WT_F01.10363.10363.2 0.00764 20-Oct K.LSAMMGAVAEK[136.11].K "sp|Q86U44|MTA70_HUMAN,tr|F5H6D8|F5H6D8_HUMAN,tr|H0YFV6|H0YFV6_HUMAN,tr|B4DTN4|B4DTN4_HUMAN" 4 1114.5606 0.02 1056 10363 2 1114.561892 558.2876 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 6 2550.2 - 280994 - - - 1.1574 - 1.894 0.336 - 152.7 1 2 0 0.0013 11 0 0 0 2.46E+07 1.51E+09 - - - 3.2501 0.9808 221125_WJC_METTL3_EV_vs_WT_F01.10366.10366.2 3.18 14-Jun R.VITALVER[166.11].T "sp|P52732|KIF11_HUMAN,tr|A0A7I2YQY4|A0A7I2YQY4_HUMAN,tr|A0A7I2V3A9|A0A7I2V3A9_HUMAN,tr|A0A7I2V3V3|A0A7I2V3V3_HUMAN" 4 909.5523 4.24 1057 10366 2 909.551773 455.7834 Kinesin-like protein KIF11 OS=Homo sapiens OX=9606 GN=KIF11 PE=1 SV=2 5.97 2550.7 - 242158 - - - -0.5651 - 1.18 0.091 - 119 1 2 0 -0.0005 8 0 0 0 3.13E+09 7.39E+08 - - - 0.2121 0.9994 221125_WJC_METTL3_EV_vs_WT_F01.10371.10371.2 0.0118 26-May R.SLYASSPGGVYATR[166.11].S "sp|P08670|VIME_HUMAN,tr|B0YJC4|B0YJC4_HUMAN,tr|A0A1B0GVG8|A0A1B0GVG8_HUMAN,tr|A0A1B0GTT5|A0A1B0GTT5_HUMAN" 4 1437.7128 1.99 1058 10371 2 1437.712228 719.8637 Vimentin OS=Homo sapiens OX=9606 GN=VIM PE=1 SV=4 8.31 2551.5 - 54088.3 - - - -0.3728 - 1.301 0.427 - 47.9 1 2 0 -0.0005 14 0 0 0 1.16E+07 5.85E+06 - - - 2.855 0.9997 221125_WJC_METTL3_EV_vs_WT_F01.10376.10376.2 0.00315 14-Aug R.VITALVER.T "sp|P52732|KIF11_HUMAN,tr|A0A7I2YQY4|A0A7I2YQY4_HUMAN,tr|A0A7I2V3A9|A0A7I2V3A9_HUMAN,tr|A0A7I2V3V3|A0A7I2V3V3_HUMAN" 4 899.544 4.24 1059 10376 2 899.543085 450.7793 Kinesin-like protein KIF11 OS=Homo sapiens OX=9606 GN=KIF11 PE=1 SV=2 5.97 2552.3 - 2.49E+06 - - - -1.0361 - 1.808 0.383 - 201.9 1 2 0 -0.0009 8 0 0 0 3.13E+09 7.39E+08 - - - 3.6557 0.9967 221125_WJC_METTL3_EV_vs_WT_F01.10397.10397.2 1.81 12-Jun R.LILPEAK[136.11].V "sp|O75147|OBSL1_HUMAN,tr|A6NN50|A6NN50_HUMAN,tr|A8MSZ8|A8MSZ8_HUMAN" 3 790.5044 0.99 1068 10397 2 790.503501 396.2595 Obscurin-like protein 1 OS=Homo sapiens OX=9606 GN=OBSL1 PE=1 SV=4 6 2555.1 - 641053 - - - -1.1259 - 1.084 0.311 - 119.8 1 2 0 -0.0009 7 0 0 0 3.94E+07 4.00E+07 - - - 1.5933 0.9128 221125_WJC_METTL3_EV_vs_WT_F01.10402.10402.2 0.00777 20-May K.LSAMMGAVAEK.K "sp|Q86U44|MTA70_HUMAN,tr|F5H6D8|F5H6D8_HUMAN,tr|H0YFV6|H0YFV6_HUMAN,tr|B4DTN4|B4DTN4_HUMAN" 4 1106.5464 0.02 1070 10402 2 1107.546527 554.2805 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 6 2555.9 - 211566 - - - 903.8256 - 1.636 0.406 - 51.5 2 2 0 1.0001 11 0 0 0 2.46E+07 1.51E+09 - - - 2.9229 0.9997 221125_WJC_METTL3_EV_vs_WT_F01.10406.10406.2 5.76E-05 13/26 R.SLYASSPGGVYATR.S "sp|P08670|VIME_HUMAN,tr|B0YJC4|B0YJC4_HUMAN,tr|A0A1B0GVG8|A0A1B0GVG8_HUMAN,tr|A0A1B0GTT5|A0A1B0GTT5_HUMAN" 4 1427.7045 2.01 1072 10406 2 1427.701942 714.8595 Vimentin OS=Homo sapiens OX=9606 GN=VIM PE=1 SV=4 8.31 2556.4 - 340908 - - - -1.7875 - 1.871 0.55 - 319.6 1 2 0 -0.0026 14 0 0 0 1.17E+07 5.85E+06 - - - 4.6746 0.9911 221125_WJC_METTL3_EV_vs_WT_F01.10431.10431.2 1.29 12-Jul R.LNELLVK[136.11].A "sp|Q12931|TRAP1_HUMAN,tr|I3L0K7|I3L0K7_HUMAN,tr|I3L253|I3L253_HUMAN" 3 835.5259 1.74 1083 10431 2 835.523585 418.7702 "Heat shock protein 75 kDa, mitochondrial OS=Homo sapiens OX=9606 GN=TRAP1 PE=1 SV=3" 6 2559.7 - 2.57E+06 - - - -2.7157 - 1.867 0.083 - 143.5 1 2 0 -0.0023 7 0 0 0 4.36E+08 2.50E+08 - - - 1.6316 0.8778 221125_WJC_METTL3_EV_vs_WT_F01.10448.10448.2 0.799 14-Jun R.AIVPLEAR.M "sp|O14776|TCRG1_HUMAN,tr|A0A7P0T8N8|A0A7P0T8N8_HUMAN,tr|G3V220|G3V220_HUMAN" 3 867.5178 1.91 1092 10448 2 867.515017 434.7662 Transcription elongation regulator 1 OS=Homo sapiens OX=9606 GN=TCERG1 PE=1 SV=2 6.05 2562 - 403675 - - - -3.2103 - 1.294 0.052 - 106.4 3 2 0 -0.0028 8 0 0 0 1.36E+08 7.12E+07 - - - -0.0116 0.9997 221125_WJC_METTL3_EV_vs_WT_F01.10449.10449.2 1.18E-05 22-Oct R.FLEQQNQVLQTK.W "sp|Q7Z794|K2C1B_HUMAN,sp|P04264|K2C1_HUMAN,sp|P35908|K22E_HUMAN" 3 1474.778 2921.23 1093 10449 2 1474.775017 738.3963 "Keratin, type II cytoskeletal 1b OS=Homo sapiens OX=9606 GN=KRT77 PE=1 SV=3" 6 2562.2 - 227112 - - - -2.0179 - 2.11 0.466 - 287.5 1 2 0 -0.003 12 0 0 0 9.61E+07 3.29E+04 - - - 4.4466 0.996 221125_WJC_METTL3_EV_vs_WT_F01.10454.10454.2 1.11 14-Jun R.LLVVTDPR[166.11].A "sp|P08865|RSSA_HUMAN,tr|C9J9K3|C9J9K3_HUMAN,tr|A0A0C4DG17|A0A0C4DG17_HUMAN" 3 921.5523 0.77 1096 10454 2 921.552104 461.7834 40S ribosomal protein SA OS=Homo sapiens OX=9606 GN=RPSA PE=1 SV=4 5.84 2562.8 - 664827 - - - -0.1986 - 1.38 0.169 - 138.7 1 2 0 -0.0002 8 0 0 0 5.94E+08 7.67E+08 - - - 1.2606 0.9919 221125_WJC_METTL3_EV_vs_WT_F01.10456.10456.2 0.05 14-Jun R.LPLETAYR.R "sp|P58107|EPIPL_HUMAN,tr|A0A075B730|A0A075B730_HUMAN" 2 961.5233 2.67 1098 10456 2 961.520699 481.7689 Epiplakin OS=Homo sapiens OX=9606 GN=EPPK1 PE=1 SV=3 6 2563.1 - 1.05E+06 - - - -2.6864 - 1.226 0.275 - 65.5 1 2 0 -0.0026 8 0 0 0 2.30E+07 8.61E+06 - - - 1.6859 0.9974 221125_WJC_METTL3_EV_vs_WT_F01.10460.10460.2 0.0663 14-Jul R.LPLETAYR[166.11].R "sp|P58107|EPIPL_HUMAN,tr|A0A075B730|A0A075B730_HUMAN" 2 971.5316 2.54 1099 10460 2 971.530808 486.7731 Epiplakin OS=Homo sapiens OX=9606 GN=EPPK1 PE=1 SV=3 6 2563.6 - 303345 - - - -0.7658 - 1.333 0.236 - 179.6 1 2 0 -0.0007 8 0 0 0 2.18E+07 8.61E+06 - - - 1.6507 0.9936 221125_WJC_METTL3_EV_vs_WT_F01.10480.10480.2 0.00952 14-Sep R.VFVNPSLR[166.11].V sp|Q9HBH1|DEFM_HUMAN 1 940.537 0.97 1103 10480 2 940.535438 471.2758 "Peptide deformylase, mitochondrial OS=Homo sapiens OX=9606 GN=PDF PE=1 SV=1" 9.72 2566.7 - 1.47E+06 - - - -1.6299 - 1.393 0.17 - 250.8 1 2 0 -0.0015 8 0 0 0 1.49E+08 1.54E+08 - - - 1.2958 0.9028 221125_WJC_METTL3_EV_vs_WT_F01.10511.10511.2 0.019 14-Jul Q.VLVLAPTR[166.11].E "sp|Q9NR30|DDX21_HUMAN,sp|Q9BQ39|DDX50_HUMAN" 2 877.5625 1.09 1114 10511 2 877.560553 439.7885 Nucleolar RNA helicase 2 OS=Homo sapiens OX=9606 GN=DDX21 PE=1 SV=5 9.72 2571.2 - 1.05E+06 - - - -2.1708 - 1.541 0.312 - 283.1 1 1 0 -0.0019 8 0 0 0 4.53E+07 4.16E+07 - - - 2.649 0.9353 221125_WJC_METTL3_EV_vs_WT_F01.10525.10525.2 0.251 12-Jul R.IVELMGR[166.11].E sp|P43304|GPDM_HUMAN 1 826.461 0.9 1119 10525 2 826.458187 414.2378 "Glycerol-3-phosphate dehydrogenase, mitochondrial OS=Homo sapiens OX=9606 GN=GPD2 PE=1 SV=3" 6 2573.3 - 356494 - - - -3.4388 - 1.404 0.059 - 137.3 1 2 0 -0.0028 7 0 0 0 1.32E+07 1.46E+07 - - - 0.5511 0.9933 221125_WJC_METTL3_EV_vs_WT_F01.10545.10545.2 0.411 12-May R.LIPTELR[166.11].R "sp|Q96G21|IMP4_HUMAN,tr|F8WCN0|F8WCN0_HUMAN,tr|B8ZZ47|B8ZZ47_HUMAN,tr|H0Y714|H0Y714_HUMAN" 4 850.5152 2.99 1124 10545 2 850.513972 426.2649 U3 small nucleolar ribonucleoprotein protein IMP4 OS=Homo sapiens OX=9606 GN=IMP4 PE=1 SV=1 6 2576.2 - 754821 - - - -1.4121 - 1.158 0.244 - 93.2 2 2 0 -0.0012 7 0 0 0 2.76E+08 9.24E+07 - - - 1.1731 0.7893 221125_WJC_METTL3_EV_vs_WT_F01.10561.10561.2 0.681 12-Jul L.QGEVNIK.S sp|Q9Y5T5|UBP16_HUMAN 1 786.4236 1.76 1134 10561 2 786.423119 394.2191 Ubiquitin carboxyl-terminal hydrolase 16 OS=Homo sapiens OX=9606 GN=USP16 PE=1 SV=1 6 2578.3 - 374166 - - - -0.5709 - 1.409 0.148 - 193.5 1 1 0 -0.0004 7 0 0 0 1.30E+08 7.40E+07 - - - 1.2204 0.7707 221125_WJC_METTL3_EV_vs_WT_F01.10566.10566.2 0.213 12-Jun K.LPLVTPH.T sp|P62191|PRS4_HUMAN 1 775.4592 - 1136 10566 2 775.459138 388.7369 26S proteasome regulatory subunit 4 OS=Homo sapiens OX=9606 GN=PSMC1 PE=1 SV=1 6.74 2578.9 - 845413 - - - -0.1122 - 1.136 0.225 - 115.7 1 1 0 -0.0001 7 0 0 0 - - - - - 1.1069 0.999 221125_WJC_METTL3_EV_vs_WT_F01.10570.10570.2 0.114 14-Aug K.GIYALAAR.D "sp|O00139|KIF2A_HUMAN,tr|D6R9M0|D6R9M0_HUMAN,tr|A0A6Q8PFA6|A0A6Q8PFA6_HUMAN,tr|A0A6Q8PGG1|A0A6Q8PGG1_HUMAN,tr|A0A6Q8PGH7|A0A6Q8PGH7_HUMAN,tr|A0A6Q8PG37|A0A6Q8PG37_HUMAN,tr|A0A6Q8PH57|A0A6Q8PH57_HUMAN" 7 833.4759 1.45 1138 10570 2 833.475174 417.7452 Kinesin-like protein KIF2A OS=Homo sapiens OX=9606 GN=KIF2A PE=1 SV=3 8.75 2579.5 - 692976 - - - -0.9166 - 1.536 0.295 - 279.4 1 2 0 -0.0008 8 0 0 0 2.64E+07 1.83E+07 - - - 2.514 0.9979 221125_WJC_METTL3_EV_vs_WT_F01.10579.10579.2 0.569 14-Aug R.LLVVTDPR.A "sp|P08865|RSSA_HUMAN,tr|C9J9K3|C9J9K3_HUMAN,tr|A0A0C4DG17|A0A0C4DG17_HUMAN" 3 911.544 0.71 1141 10579 2 911.54333 456.7793 40S ribosomal protein SA OS=Homo sapiens OX=9606 GN=RPSA PE=1 SV=4 5.84 2580.7 - 2.46E+06 - - - -0.7537 - 1.812 0.136 - 216 1 2 0 -0.0007 8 0 0 0 5.42E+08 7.65E+08 - - - 1.8381 0.9954 221125_WJC_METTL3_EV_vs_WT_F01.10587.10587.2 0.0454 22-Jul K.NAGVEGSLIVEK[136.11].L "sp|P10809|CH60_HUMAN,tr|A0A7I2V2X6|A0A7I2V2X6_HUMAN,tr|A0A7I2YQK6|A0A7I2YQK6_HUMAN,tr|A0A7I2V599|A0A7I2V599_HUMAN" 4 1222.6649 1.32 1144 10587 2 1222.666178 612.3397 "60 kDa heat shock protein, mitochondrial OS=Homo sapiens OX=9606 GN=HSPD1 PE=1 SV=2" 4.53 2581.8 - 181265 - - - 1.0722 - 1.458 0.184 - 119.7 1 2 0 0.0013 12 0 0 0 1.32E+08 1.00E+08 - - - 1.3917 0.9993 221125_WJC_METTL3_EV_vs_WT_F01.10589.10589.2 0.000187 22-Sep K.NAGVEGSLIVEK.L "sp|P10809|CH60_HUMAN,tr|A0A7I2V2X6|A0A7I2V2X6_HUMAN,tr|A0A7I2YQK6|A0A7I2YQK6_HUMAN,tr|A0A7I2V599|A0A7I2V599_HUMAN" 4 1214.6507 1.32 1145 10589 2 1214.647966 608.3326 "60 kDa heat shock protein, mitochondrial OS=Homo sapiens OX=9606 GN=HSPD1 PE=1 SV=2" 4.53 2582 - 262332 - - - -2.2237 - 1.747 0.437 - 244.8 1 2 0 -0.0027 12 0 0 0 1.32E+08 1.00E+08 - - - 3.7358 0.9935 221125_WJC_METTL3_EV_vs_WT_F01.10599.10599.2 0.352 12-Aug K.FIEIAAR.K "sp|Q00839|HNRPU_HUMAN,tr|A0A1W2PQL0|A0A1W2PQL0_HUMAN,tr|A0A1W2PPE9|A0A1W2PPE9_HUMAN,tr|A0A1W2PPL4|A0A1W2PPL4_HUMAN,tr|A0A1W2PQ74|A0A1W2PQ74_HUMAN,tr|Q5RI18|Q5RI18_HUMAN,tr|A0A1W2PP35|A0A1W2PP35_HUMAN,tr|A0A1W2PPS1|A0A1W2PPS1_HUMAN,tr|A0A1W2PRZ7|A0A1W2PRZ7_HUMAN,tr|A0A1W2PPH7|A0A1W2PPH7_HUMAN,tr|A0A1W2PQD4|A0A1W2PQD4_HUMAN,tr|A0A1W2PP34|A0A1W2PP34_HUMAN,tr|A0A1X7SBS1|A0A1X7SBS1_HUMAN" 13 818.465 0.98 1148 10599 2 818.46386 410.2398 Heterogeneous nuclear ribonucleoprotein U OS=Homo sapiens OX=9606 GN=HNRNPU PE=1 SV=6 6 2583.4 - 2.26E+06 - - - -1.4393 - 1.321 0.174 - 244.6 1 2 0 -0.0012 7 0 0 0 1.90E+10 1.94E+10 - - - 1.2079 0.9658 221125_WJC_METTL3_EV_vs_WT_F01.10615.10615.2 0.943 12-Jul R.VYLGALK[136.11].Y sp|Q6P2Q9|PRP8_HUMAN 1 770.4782 1.01 1154 10615 2 770.47668 386.2464 Pre-mRNA-processing-splicing factor 8 OS=Homo sapiens OX=9606 GN=PRPF8 PE=1 SV=2 8.56 2585.7 - 1.61E+06 - - - -1.9417 - 1.256 0.069 - 168.1 1 2 0 -0.0015 7 0 0 0 1.20E+08 1.18E+08 - - - 0.2724 0.9882 221125_WJC_METTL3_EV_vs_WT_F01.10630.10630.2 0.299 12-Jun K.IIMGLDK[136.11].M sp|P52298|NCBP2_HUMAN 1 796.4608 1.36 1158 10630 2 796.458316 399.2377 Nuclear cap-binding protein subunit 2 OS=Homo sapiens OX=9606 GN=NCBP2 PE=1 SV=1 5.84 2588 - 1.66E+06 - - - -3.1326 - 1.325 0.232 - 101.5 1 2 0 -0.0025 7 0 0 0 1.65E+08 1.22E+08 - - - 1.6454 0.9998 221125_WJC_METTL3_EV_vs_WT_F01.10632.10632.2 2.68E-06 20-Oct R.QGVDADINGLR.Q "sp|P35527|K1C9_HUMAN,tr|K7EQQ3|K7EQQ3_HUMAN" 2 1156.5837 85.48 1160 10632 2 1156.582626 579.2991 "Keratin, type I cytoskeletal 9 OS=Homo sapiens OX=9606 GN=KRT9 PE=1 SV=3" 4.21 2588.2 - 346387 - - - -0.8854 - 1.874 0.51 - 326.9 1 2 0 -0.001 11 0 0 0 2.49E+07 2.91E+05 - - - 4.5066 0.9814 221125_WJC_METTL3_EV_vs_WT_F01.10637.10637.2 0.0594 12-Jul K.DDAMLLK.G "sp|P10809|CH60_HUMAN,tr|A0A7I2V2X6|A0A7I2V2X6_HUMAN,tr|A0A7I2YQK6|A0A7I2YQK6_HUMAN,tr|A0A7I2V599|A0A7I2V599_HUMAN" 4 804.4051 1.17 1161 10637 2 804.40261 403.2098 "60 kDa heat shock protein, mitochondrial OS=Homo sapiens OX=9606 GN=HSPD1 PE=1 SV=2" 4.21 2589 - 353771 - - - -3.1452 - 1.347 0.179 - 191.6 1 2 0 -0.0025 7 0 0 0 2.87E+07 2.45E+07 - - - 1.3061 0.968 221125_WJC_METTL3_EV_vs_WT_F01.10641.10641.2 1.02 12-Jun K.LGITQLR[166.11].F "sp|Q9Y285|SYFA_HUMAN,tr|K7EPH2|K7EPH2_HUMAN,tr|K7ER00|K7ER00_HUMAN" 3 809.4999 1.7 1162 10641 2 809.499898 405.7572 Phenylalanine--tRNA ligase alpha subunit OS=Homo sapiens OX=9606 GN=FARSA PE=1 SV=3 9.75 2589.5 - 581482 - - - 0.0494 - 1.292 0 - 82.8 1 2 0 0 7 0 0 0 7.38E+07 4.34E+07 - - - -0.1473 0.8281 221125_WJC_METTL3_EV_vs_WT_F01.10674.10674.2 2.67 12-Jun R.VTVPLVR.R "sp|Q9UKM9|RALY_HUMAN,tr|Q5QPM0|Q5QPM0_HUMAN,tr|Q5QPM1|Q5QPM1_HUMAN,tr|Q5QPL9|Q5QPL9_HUMAN" 4 782.5014 1.15 1168 10674 2 782.496991 392.258 RNA-binding protein Raly OS=Homo sapiens OX=9606 GN=RALY PE=1 SV=1 9.72 2594.5 - 671415 - - - -5.6652 - 1.135 0.197 - 120.9 1 2 0 -0.0044 7 0 0 0 2.75E+08 2.40E+08 - - - 0.8959 0.9161 221125_WJC_METTL3_EV_vs_WT_F01.10677.10677.2 0.465 14-Aug K.IEISELNR.V "sp|P04264|K2C1_HUMAN,sp|P35908|K22E_HUMAN" 2 972.524 86.94 1169 10677 2 972.520058 487.2693 "Keratin, type II cytoskeletal 1 OS=Homo sapiens OX=9606 GN=KRT1 PE=1 SV=6" 4.53 2594.9 - 1.41E+06 - - - -4.0637 - 1.479 0.079 - 172.4 2 2 0 -0.004 8 0 0 0 7.25E+07 8.34E+05 - - - 0.6691 0.9778 221125_WJC_METTL3_EV_vs_WT_F01.10687.10687.2 0.772 12-Jun R.VTVPLVR[166.11].R "sp|Q9UKM9|RALY_HUMAN,tr|Q5QPM0|Q5QPM0_HUMAN,tr|Q5QPM1|Q5QPM1_HUMAN,tr|Q5QPL9|Q5QPL9_HUMAN" 4 792.5097 1.17 1172 10687 2 792.506811 397.2621 RNA-binding protein Raly OS=Homo sapiens OX=9606 GN=RALY PE=1 SV=1 9.72 2596.4 - 1.47E+06 - - - -3.6378 - 1.471 0.159 - 141.1 1 2 0 -0.0029 7 0 0 0 2.75E+08 2.35E+08 - - - 1.4373 0.9992 221125_WJC_METTL3_EV_vs_WT_F01.10701.10701.2 0.00375 20-Jul K.IGGIGTVPVGR.V "sp|Q05639|EF1A2_HUMAN,sp|P68104|EF1A1_HUMAN,sp|Q5VTE0|EF1A3_HUMAN,tr|A0A7I2V659|A0A7I2V659_HUMAN,tr|A0A7I2V3H3|A0A7I2V3H3_HUMAN,tr|A0A2U3TZH3|A0A2U3TZH3_HUMAN,tr|A0A7I2V5N4|A0A7I2V5N4_HUMAN,tr|A0A087WVQ9|A0A087WVQ9_HUMAN" 8 1024.6029 4.03 1178 10701 2 1024.601707 513.3087 Elongation factor 1-alpha 2 OS=Homo sapiens OX=9606 GN=EEF1A2 PE=1 SV=1 9.75 2598.1 - 232733 - - - -1.1927 - 1.76 0.325 - 129.1 2 2 0 -0.0012 11 0 0 0 8.57E+07 2.13E+07 - - - 2.8359 0.9795 221125_WJC_METTL3_EV_vs_WT_F01.10703.10703.3 0.0765 Jun-40 K.IWHHTFYNELR.V "sp|Q6S8J3|POTEE_HUMAN,sp|P63261|ACTG_HUMAN,sp|P68133|ACTS_HUMAN,sp|Q9BYX7|ACTBM_HUMAN,sp|P68032|ACTC_HUMAN,sp|P60709|ACTB_HUMAN,sp|A5A3E0|POTEF_HUMAN,sp|P0CG38|POTEI_HUMAN,sp|P0CG39|POTEJ_HUMAN,tr|A0A804GS07|A0A804GS07_HUMAN,tr|I3L3I0|I3L3I0_HUMAN,tr|G5E9R0|G5E9R0_HUMAN,tr|E7EVS6|E7EVS6_HUMAN,tr|A0A6Q8PFE4|A0A6Q8PFE4_HUMAN,tr|J3KT65|J3KT65_HUMAN,tr|I3L3R2|I3L3R2_HUMAN,tr|K7EM38|K7EM38_HUMAN,tr|A0A6Q8PH58|A0A6Q8PH58_HUMAN,tr|I3L1U9|I3L1U9_HUMAN,tr|A0A804HKV3|A0A804HKV3_HUMAN,tr|A0A2R8Y793|A0A2R8Y793_HUMAN,tr|I3L4N8|I3L4N8_HUMAN,tr|C9JUM1|C9JUM1_HUMAN,tr|C9JZR7|C9JZR7_HUMAN,tr|A0A2R8YGF8|A0A2R8YGF8_HUMAN,tr|A6NL76|A6NL76_HUMAN" 26 1514.7419 2.17 1179 10703 3 1514.740841 505.9212 POTE ankyrin domain family member E OS=Homo sapiens OX=9606 GN=POTEE PE=2 SV=3 6.92 2598.3 - 225040 - - - -0.6872 - 1.334 0.181 - 36.3 1 2 0 -0.001 11 0 0 0 9.81E+06 4.52E+06 - - - 1.3764 0.999 221125_WJC_METTL3_EV_vs_WT_F01.10717.10717.2 0.0103 12-Jul K.LPYSTFR[166.11].T "sp|Q13207|TBX2_HUMAN,sp|O15119|TBX3_HUMAN" 2 892.4682 1.46 1184 10717 2 892.46663 447.2414 T-box transcription factor TBX2 OS=Homo sapiens OX=9606 GN=TBX2 PE=1 SV=3 8.75 2600.2 - 3.27E+06 - - - -1.7849 - 1.326 0.415 - 210.3 1 2 0 -0.0016 7 0 0 0 3.90E+08 2.68E+08 - - - 2.9998 0.8126 221125_WJC_METTL3_EV_vs_WT_F01.10739.10739.2 18.8 14-May R.LLGDPGLR[166.11].G sp|Q2M3V2|SWAHA_HUMAN 1 849.4948 1.26 1195 10739 2 849.492866 425.7547 Ankyrin repeat domain-containing protein SOWAHA OS=Homo sapiens OX=9606 GN=SOWAHA PE=1 SV=3 5.84 2603.2 - 309101 - - - -2.2437 - 1.115 0 - 63.9 2 2 0 -0.0019 8 0 0 0 1.50E+07 1.19E+07 - - - -0.7658 0.9824 221125_WJC_METTL3_EV_vs_WT_F01.10742.10742.2 2.26 12-Jun K.FIEIAAR[166.11].K "sp|Q00839|HNRPU_HUMAN,tr|A0A1W2PQL0|A0A1W2PQL0_HUMAN,tr|A0A1W2PPE9|A0A1W2PPE9_HUMAN,tr|A0A1W2PPL4|A0A1W2PPL4_HUMAN,tr|A0A1W2PQ74|A0A1W2PQ74_HUMAN,tr|Q5RI18|Q5RI18_HUMAN,tr|A0A1W2PP35|A0A1W2PP35_HUMAN,tr|A0A1W2PPS1|A0A1W2PPS1_HUMAN,tr|A0A1W2PRZ7|A0A1W2PRZ7_HUMAN,tr|A0A1W2PPH7|A0A1W2PPH7_HUMAN,tr|A0A1W2PQD4|A0A1W2PQD4_HUMAN,tr|A0A1W2PP34|A0A1W2PP34_HUMAN,tr|A0A1X7SBS1|A0A1X7SBS1_HUMAN" 13 828.4733 0.98 1197 10742 2 828.472188 415.2439 Heterogeneous nuclear ribonucleoprotein U OS=Homo sapiens OX=9606 GN=HNRNPU PE=1 SV=6 6 2603.6 - 4.14E+06 - - - -1.3519 - 1.256 0.096 - 144.1 1 2 0 -0.0011 7 0 0 0 1.90E+10 1.94E+10 - - - 0.4719 0.9967 221125_WJC_METTL3_EV_vs_WT_F01.10744.10744.2 0.0399 12-Jul K.LPYSTFR.T "sp|Q13207|TBX2_HUMAN,sp|O15119|TBX3_HUMAN" 2 882.46 1.46 1198 10744 2 882.458873 442.2373 T-box transcription factor TBX2 OS=Homo sapiens OX=9606 GN=TBX2 PE=1 SV=3 8.75 2603.8 - 2.99E+06 - - - -1.2239 - 1.225 0.261 - 209.1 1 2 0 -0.0011 7 0 0 0 3.90E+08 2.68E+08 - - - 1.6114 0.9638 221125_WJC_METTL3_EV_vs_WT_F01.10756.10756.2 2.6 20-Jul K.LSAMMGAVAEK[136.11].K "sp|Q86U44|MTA70_HUMAN,tr|F5H6D8|F5H6D8_HUMAN,tr|H0YFV6|H0YFV6_HUMAN,tr|B4DTN4|B4DTN4_HUMAN" 4 1114.5606 0.01 1204 10756 2 1114.559008 558.2876 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 6 2605.4 - 88429.4 - - - -1.4302 - 1 0.133 - 70.1 1 2 0 -0.0016 11 0 0 0 3.09E+04 5.91E+06 - - - 0.0228 0.9994 221125_WJC_METTL3_EV_vs_WT_F01.10759.10759.2 0.0289 20-Nov K.IGGIGTVPVGR[166.11].V "sp|Q05639|EF1A2_HUMAN,sp|P68104|EF1A1_HUMAN,sp|Q5VTE0|EF1A3_HUMAN,tr|A0A7I2V659|A0A7I2V659_HUMAN,tr|A0A7I2V3H3|A0A7I2V3H3_HUMAN,tr|A0A2U3TZH3|A0A2U3TZH3_HUMAN,tr|A0A7I2V5N4|A0A7I2V5N4_HUMAN,tr|A0A087WVQ9|A0A087WVQ9_HUMAN" 8 1034.6112 5.62 1205 10759 2 1034.610245 518.3129 Elongation factor 1-alpha 2 OS=Homo sapiens OX=9606 GN=EEF1A2 PE=1 SV=1 9.75 2605.8 - 366721 - - - -0.9221 - 2.044 0.283 - 410.6 1 2 0 -0.001 11 0 0 0 8.03E+07 1.43E+07 - - - 3.0649 0.9958 221125_WJC_METTL3_EV_vs_WT_F01.10772.10772.2 0.0101 12-Jul K.FMTDPIR.L "sp|P38919|IF4A3_HUMAN,tr|I3L3H2|I3L3H2_HUMAN" 2 878.432 1.43 1210 10772 2 878.431282 440.2233 Eukaryotic initiation factor 4A-III OS=Homo sapiens OX=9606 GN=EIF4A3 PE=1 SV=4 5.84 2607.6 - 2.24E+06 - - - -0.8447 - 1.238 0.217 - 223.6 1 2 0 -0.0007 7 0 0 0 1.42E+08 9.93E+07 - - - 1.32 0.988 221125_WJC_METTL3_EV_vs_WT_F01.10774.10774.2 1.58 14-Jun K.MLDAAVIK[136.11].M sp|Q9BXP5|SRRT_HUMAN 1 867.4979 1.13 1212 10774 2 867.497962 434.7562 Serrate RNA effector molecule homolog OS=Homo sapiens OX=9606 GN=SRRT PE=1 SV=1 5.59 2607.9 - 982123 - - - 0.0427 - 1.119 0.151 - 112.9 1 2 0 0 8 0 0 0 1.01E+08 8.90E+07 - - - 0.4954 0.9841 221125_WJC_METTL3_EV_vs_WT_F01.10777.10777.2 1.46 14-Aug K.MLDAAVIK.M sp|Q9BXP5|SRRT_HUMAN 1 859.4837 1.15 1214 10777 2 859.485741 430.7491 Serrate RNA effector molecule homolog OS=Homo sapiens OX=9606 GN=SRRT PE=1 SV=1 5.59 2608.2 - 1.39E+06 - - - 2.3456 - 1.44 0.121 - 239.1 1 2 0 0.002 8 0 0 0 9.58E+07 8.33E+07 - - - 1.0338 0.9978 221125_WJC_METTL3_EV_vs_WT_F01.10779.10779.2 0.0487 12-Jul K.FMTDPIR[166.11].L "sp|P38919|IF4A3_HUMAN,tr|I3L3H2|I3L3H2_HUMAN" 2 888.4403 1.43 1215 10779 2 888.439665 445.2274 Eukaryotic initiation factor 4A-III OS=Homo sapiens OX=9606 GN=EIF4A3 PE=1 SV=4 5.84 2608.5 - 1.99E+06 - - - -0.708 - 1.253 0.275 - 218.6 1 2 0 -0.0006 7 0 0 0 1.42E+08 9.93E+07 - - - 1.7866 0.9883 221125_WJC_METTL3_EV_vs_WT_F01.10782.10782.2 0.376 16-Jul R.MVGGVLVER.T sp|Q9UHV9|PFD2_HUMAN 1 958.527 0.57 1218 10782 2 958.523625 480.2708 Prefoldin subunit 2 OS=Homo sapiens OX=9606 GN=PFDN2 PE=1 SV=1 5.75 2608.8 - 314273 - - - -3.5075 - 1.505 0.223 - 149.3 1 2 0 -0.0034 9 0 0 0 4.24E+07 7.38E+07 - - - 1.8697 0.9968 221125_WJC_METTL3_EV_vs_WT_F01.10801.10801.2 0.0155 14-Aug R.VLAVTAIR[166.11].E sp|P22102|PUR2_HUMAN 1 851.5468 0.72 1226 10801 2 851.547545 426.7807 Trifunctional purine biosynthetic protein adenosine-3 OS=Homo sapiens OX=9606 GN=GART PE=1 SV=1 9.72 2611.5 - 141314 - - - 0.8655 - 1.767 0.114 - 170.3 1 2 0 0.0007 8 0 0 0 1.88E+08 2.62E+08 - - - 1.5997 0.9939 221125_WJC_METTL3_EV_vs_WT_F01.10805.10805.2 0.193 14-May K.LLAESLPR.R sp|Q5THJ4|VP13D_HUMAN 1 897.5284 0.08 1228 10805 2 897.528005 449.7715 Vacuolar protein sorting-associated protein 13D OS=Homo sapiens OX=9606 GN=VPS13D PE=1 SV=2 6 2611.9 - 213918 - - - -0.4033 - 0.997 0.263 - 52.1 1 2 0 -0.0004 8 0 0 0 1.85E+07 2.30E+08 - - - 0.9743 0.9998 221125_WJC_METTL3_EV_vs_WT_F01.10816.10816.2 0.000558 12-Jul K.MMVAGFK.K "sp|Q00839|HNRPU_HUMAN,tr|A0A1W2PQL0|A0A1W2PQL0_HUMAN,tr|A0A1W2PPL4|A0A1W2PPL4_HUMAN,tr|A0A1W2PQ74|A0A1W2PQ74_HUMAN,tr|Q5RI18|Q5RI18_HUMAN,tr|A0A1W2PP35|A0A1W2PP35_HUMAN,tr|A0A1W2PPS1|A0A1W2PPS1_HUMAN,tr|A0A1W2PRZ7|A0A1W2PRZ7_HUMAN,tr|A0A1W2PPH7|A0A1W2PPH7_HUMAN,tr|A0A1W2PQD4|A0A1W2PQD4_HUMAN,tr|A0A1W2PP34|A0A1W2PP34_HUMAN,tr|A0A1X7SBS1|A0A1X7SBS1_HUMAN" 12 782.3819 0.95 1234 10816 2 782.381173 392.1982 Heterogeneous nuclear ribonucleoprotein U OS=Homo sapiens OX=9606 GN=HNRNPU PE=1 SV=6 8.5 2613.4 - 8.42E+06 - - - -0.9318 - 1.642 0.553 - 244.2 1 2 0 -0.0007 7 0 0 0 3.79E+09 4.01E+09 - - - 4.6966 0.9859 221125_WJC_METTL3_EV_vs_WT_F01.10819.10819.2 0.297 12-Aug R.MLVELSK[136.11].A sp|P50991|TCPD_HUMAN 1 826.4714 0.22 1235 10819 2 826.468674 414.243 T-complex protein 1 subunit delta OS=Homo sapiens OX=9606 GN=CCT4 PE=1 SV=4 5.75 2613.9 - 2.28E+06 - - - -3.2693 - 1.525 0.163 - 295.7 1 2 0 -0.0027 7 0 0 0 1.24E+08 5.59E+08 - - - 1.5812 0.9972 221125_WJC_METTL3_EV_vs_WT_F01.10820.10820.2 0.000493 12-Aug K.MMEIMTR[166.11].E "sp|P61247|RS3A_HUMAN,tr|H0Y8L7|H0Y8L7_HUMAN,tr|D6R9B6|D6R9B6_HUMAN,tr|H0Y9Y4|H0Y9Y4_HUMAN,tr|D6RB09|D6RB09_HUMAN,tr|E9PFI5|E9PFI5_HUMAN,tr|D6RAT0|D6RAT0_HUMAN,tr|D6RG13|D6RG13_HUMAN" 8 920.4157 0.83 1236 10820 2 920.414793 461.2151 40S ribosomal protein S3a OS=Homo sapiens OX=9606 GN=RPS3A PE=1 SV=2 5.75 2614 - 1.00E+06 - - - -1.0235 - 1.289 0.247 - 223.6 1 2 0 -0.0009 7 0 0 0 1.01E+08 1.22E+08 - - - 1.6694 0.9922 221125_WJC_METTL3_EV_vs_WT_F01.10825.10825.2 0.155 12-Jul K.LAPFIAK[136.11].R "sp|P22830|HEMH_HUMAN,tr|A0A499FJN5|A0A499FJN5_HUMAN,tr|K7ELX4|K7ELX4_HUMAN" 3 766.4833 0.89 1239 10825 2 766.482341 384.2489 "Ferrochelatase, mitochondrial OS=Homo sapiens OX=9606 GN=FECH PE=1 SV=2" 8.75 2614.6 - 887730 - - - -1.2003 - 1.439 0.106 - 170.4 1 2 0 -0.0009 7 0 0 0 2.90E+08 3.25E+08 - - - 0.9768 0.9991 221125_WJC_METTL3_EV_vs_WT_F01.10829.10829.2 1.15 14-Sep R.VLAVTAIR.E sp|P22102|PUR2_HUMAN 1 841.5385 0.72 1241 10829 2 841.537126 421.7765 Trifunctional purine biosynthetic protein adenosine-3 OS=Homo sapiens OX=9606 GN=GART PE=1 SV=1 9.72 2615.2 - 993166 - - - -1.6779 - 1.948 0.255 - 352.6 1 2 0 -0.0014 8 0 0 0 1.88E+08 2.62E+08 - - - 2.935 0.9967 221125_WJC_METTL3_EV_vs_WT_F01.10831.10831.2 0.154 12-Jul K.LAPFIAK.R "sp|P22830|HEMH_HUMAN,tr|A0A499FJN5|A0A499FJN5_HUMAN,tr|K7ELX4|K7ELX4_HUMAN" 3 758.4691 0.9 1243 10831 2 758.467899 380.2418 "Ferrochelatase, mitochondrial OS=Homo sapiens OX=9606 GN=FECH PE=1 SV=2" 8.75 2615.4 - 513260 - - - -1.532 - 1.58 0.172 - 166.8 1 2 0 -0.0012 7 0 0 0 2.90E+08 3.24E+08 - - - 1.7604 0.9986 221125_WJC_METTL3_EV_vs_WT_F01.10835.10835.2 0.127 12-Jul R.IVYLYTK[136.11].K sp|P49207|RL34_HUMAN 1 906.5306 0.84 1244 10835 2 906.529088 454.2726 60S ribosomal protein L34 OS=Homo sapiens OX=9606 GN=RPL34 PE=1 SV=3 8.5 2616 - 2.74E+06 - - - -1.6734 - 1.574 0.279 - 172.1 1 2 0 -0.0015 7 0 0 0 4.39E+08 5.25E+08 - - - 2.5385 0.8351 221125_WJC_METTL3_EV_vs_WT_F01.10841.10841.2 5.53 14-Jul K.IVGYVLAK[136.11].M "sp|Q9BSU3|NAA11_HUMAN,sp|P41227|NAA10_HUMAN,tr|A8MWP7|A8MWP7_HUMAN,tr|F8W808|F8W808_HUMAN" 4 869.5466 0.56 1246 10841 2 869.545162 435.7806 N-alpha-acetyltransferase 11 OS=Homo sapiens OX=9606 GN=NAA11 PE=1 SV=3 8.59 2616.8 - 772868 - - - -1.6422 - 0.987 0.01 - 103.1 1 2 0 -0.0014 8 0 0 0 1.07E+08 1.90E+08 - - - -0.9251 0.9996 221125_WJC_METTL3_EV_vs_WT_F01.10851.10851.2 0.00398 12-Aug K.MMEIMTR.E "sp|P61247|RS3A_HUMAN,tr|H0Y8L7|H0Y8L7_HUMAN,tr|D6R9B6|D6R9B6_HUMAN,tr|H0Y9Y4|H0Y9Y4_HUMAN,tr|D6RB09|D6RB09_HUMAN,tr|E9PFI5|E9PFI5_HUMAN,tr|D6RAT0|D6RAT0_HUMAN,tr|D6RG13|D6RG13_HUMAN" 8 910.4075 0.83 1248 10851 2 910.405724 456.211 40S ribosomal protein S3a OS=Homo sapiens OX=9606 GN=RPS3A PE=1 SV=2 5.75 2618.3 - 2.29E+06 - - - -1.9123 - 1.711 0.451 - 347.7 1 2 0 -0.0017 7 0 0 0 1.01E+08 1.22E+08 - - - 4.0733 0.9955 221125_WJC_METTL3_EV_vs_WT_F01.10859.10859.2 0.25 14-Sep K.IVGYVLAK.M "sp|Q9BSU3|NAA11_HUMAN,sp|P41227|NAA10_HUMAN,tr|A8MWP7|A8MWP7_HUMAN,tr|F8W808|F8W808_HUMAN" 4 861.5324 0.56 1251 10859 2 861.530063 431.7735 N-alpha-acetyltransferase 11 OS=Homo sapiens OX=9606 GN=NAA11 PE=1 SV=3 8.59 2619.4 - 1.29E+06 - - - -2.701 - 1.468 0.267 - 176.5 1 2 0 -0.0023 8 0 0 0 1.07E+08 1.90E+08 - - - 2.1702 0.9889 221125_WJC_METTL3_EV_vs_WT_F01.10885.10885.2 0.383 14-Aug K.FGPALSVK.V "sp|Q9H361|PABP3_HUMAN,sp|P11940|PABP1_HUMAN,tr|A0A7I2YQE4|A0A7I2YQE4_HUMAN,tr|A0A7I2V649|A0A7I2V649_HUMAN,tr|H0YAR2|H0YAR2_HUMAN,tr|E7ERJ7|E7ERJ7_HUMAN,tr|A0A7I2YQ88|A0A7I2YQ88_HUMAN,tr|H0YBN4|H0YBN4_HUMAN,tr|A0A087WTT1|A0A087WTT1_HUMAN,tr|H0YAP2|H0YAP2_HUMAN,tr|A0A7I2YQ90|A0A7I2YQ90_HUMAN,tr|A0A7I2V4N4|A0A7I2V4N4_HUMAN,tr|E7EQV3|E7EQV3_HUMAN" 13 817.4698 1.29 1258 10885 2 817.467243 409.7422 Polyadenylate-binding protein 3 OS=Homo sapiens OX=9606 GN=PABPC3 PE=1 SV=2 8.75 2623.1 - 5.37E+06 - - - -3.1157 - 1.67 0.148 - 186.6 1 2 0 -0.0025 8 0 0 0 3.76E+08 2.93E+08 - - - 1.68 0.9404 221125_WJC_METTL3_EV_vs_WT_F01.10941.10941.2 5.11 12-Jun R.FPGAYLK[136.11].G "sp|P41252|SYIC_HUMAN,tr|A0A804HL54|A0A804HL54_HUMAN,tr|A0A804HKU1|A0A804HKU1_HUMAN,tr|A0A804HK69|A0A804HK69_HUMAN,tr|A0A804HIV9|A0A804HIV9_HUMAN,tr|A0A804HJN6|A0A804HJN6_HUMAN,tr|A0A804HHW9|A0A804HHW9_HUMAN,tr|A0A0A0MSX9|A0A0A0MSX9_HUMAN,tr|J3KR24|J3KR24_HUMAN,tr|A0A804HIG2|A0A804HIG2_HUMAN,tr|A0A804HJ36|A0A804HJ36_HUMAN" 11 802.4469 0.83 1281 10941 2 802.445809 402.2307 "Isoleucine--tRNA ligase, cytoplasmic OS=Homo sapiens OX=9606 GN=IARS1 PE=1 SV=2" 8.59 2630.8 - 601640 - - - -1.3297 - 1.042 0.066 - 76.6 1 2 0 -0.0011 7 0 0 0 6.93E+07 8.34E+07 - - - -0.3415 0.9907 221125_WJC_METTL3_EV_vs_WT_F01.10963.10963.2 0.259 12-Jul R.FPGAYLK.G "sp|P41252|SYIC_HUMAN,tr|A0A804HL54|A0A804HL54_HUMAN,tr|A0A804HKU1|A0A804HKU1_HUMAN,tr|A0A804HK69|A0A804HK69_HUMAN,tr|A0A804HIV9|A0A804HIV9_HUMAN,tr|A0A804HJN6|A0A804HJN6_HUMAN,tr|A0A804HHW9|A0A804HHW9_HUMAN,tr|A0A0A0MSX9|A0A0A0MSX9_HUMAN,tr|J3KR24|J3KR24_HUMAN,tr|A0A804HIG2|A0A804HIG2_HUMAN,tr|A0A804HJ36|A0A804HJ36_HUMAN" 11 794.4327 0.7 1291 10963 2 794.432618 398.2236 "Isoleucine--tRNA ligase, cytoplasmic OS=Homo sapiens OX=9606 GN=IARS1 PE=1 SV=2" 8.59 2633.9 - 568442 - - - -0.073 - 1.262 0.12 - 111.5 1 2 0 -0.0001 7 0 0 0 4.96E+07 7.10E+07 - - - 0.6646 0.9386 221125_WJC_METTL3_EV_vs_WT_F01.10978.10978.2 1.24 12-Jul R.VAGIFPR[166.11].L "sp|O96005|CLPT1_HUMAN,tr|K7EJ16|K7EJ16_HUMAN" 2 768.4522 0.52 1295 10978 2 768.450714 385.2334 Cleft lip and palate transmembrane protein 1 OS=Homo sapiens OX=9606 GN=CLPTM1 PE=1 SV=1 9.72 2636.1 - 780718 - - - -1.9064 - 1.274 0.008 - 190.9 1 2 0 -0.0015 7 0 0 0 2.62E+07 5.01E+07 - - - -0.1331 0.87 221125_WJC_METTL3_EV_vs_WT_F01.10988.10988.2 2.38 12-Jun R.YLLYGEK[136.11].G "sp|P51398|RT29_HUMAN,tr|V9GZ03|V9GZ03_HUMAN,tr|V9GYL9|V9GYL9_HUMAN" 3 892.4786 1.67 1299 10988 2 892.482269 447.2466 "28S ribosomal protein S29, mitochondrial OS=Homo sapiens OX=9606 GN=DAP3 PE=1 SV=1" 6 2637.4 - 262470 - - - 4.1446 - 1.247 0.108 - 130.7 2 2 0 0.0037 7 0 0 0 1.91E+07 1.14E+07 - - - 0.4025 0.9593 221125_WJC_METTL3_EV_vs_WT_F01.10989.10989.2 0.913 14-May K.AITAVALK.E sp|Q9NQX4|MYO5C_HUMAN 1 785.5011 25.25 1300 10989 2 785.502206 393.7578 Unconventional myosin-Vc OS=Homo sapiens OX=9606 GN=MYO5C PE=1 SV=2 8.8 2637.6 - 111909 - - - 1.4207 - 1.068 0.104 - 54.9 1 2 0 0.0011 8 0 0 0 5.55E+06 2.20E+05 - - - 0.0072 0.9989 221125_WJC_METTL3_EV_vs_WT_F01.10992.10992.2 0.00613 20-Jun R.EEAENTLQSFR.Q "sp|P08670|VIME_HUMAN,tr|B0YJC5|B0YJC5_HUMAN,tr|B0YJC4|B0YJC4_HUMAN" 3 1322.6103 1.79 1301 10992 2 1322.610358 662.3124 Vimentin OS=Homo sapiens OX=9606 GN=VIM PE=1 SV=4 4.25 2638 - 71700.4 - - - 0.0749 - 1.196 0.369 - 67.1 1 2 0 0.0001 11 0 0 0 2.34E+06 1.30E+06 - - - 2.2506 0.9989 221125_WJC_METTL3_EV_vs_WT_F01.11010.11010.2 0.00538 14-Jul K.GLYPAPLK[136.11].L "sp|P40939|ECHA_HUMAN,tr|A0A2R8YG21|A0A2R8YG21_HUMAN,tr|A0A2R8Y688|A0A2R8Y688_HUMAN,tr|H0YFD6|H0YFD6_HUMAN,tr|A0A2R8Y4F5|A0A2R8Y4F5_HUMAN" 5 865.5153 1.13 1308 11010 2 865.515736 433.7649 "Trifunctional enzyme subunit alpha, mitochondrial OS=Homo sapiens OX=9606 GN=HADHA PE=1 SV=2" 8.59 2640.4 - 291666 - - - 0.5153 - 1.581 0.258 - 156.3 1 2 0 0.0004 8 0 0 0 3.31E+07 2.92E+07 - - - 2.3279 0.9996 221125_WJC_METTL3_EV_vs_WT_F01.11039.11039.2 0.00194 14-Aug R.LGMGLVSR.S "sp|Q8N6H7|ARFG2_HUMAN,tr|E9PIY6|E9PIY6_HUMAN,tr|E9PQP3|E9PQP3_HUMAN,tr|G5E9L0|G5E9L0_HUMAN,tr|A0A0D9SF70|A0A0D9SF70_HUMAN" 5 831.4637 1.09 1318 11039 2 831.462749 416.7391 ADP-ribosylation factor GTPase-activating protein 2 OS=Homo sapiens OX=9606 GN=ARFGAP2 PE=1 SV=1 9.75 2644.6 - 566605 - - - -1.0933 - 1.781 0.372 - 164.8 1 2 0 -0.0009 8 0 0 0 1.54E+08 1.42E+08 - - - 3.529 0.992 221125_WJC_METTL3_EV_vs_WT_F01.11043.11043.2 0.941 20-Jul R.LLASTLVHSVK.K "sp|Q9NYF8|BCLF1_HUMAN,tr|E9PKI6|E9PKI6_HUMAN,tr|A0A1W2PQ43|A0A1W2PQ43_HUMAN,tr|E9PK91|E9PK91_HUMAN,tr|E9PJA7|E9PJA7_HUMAN,tr|E9PK09|E9PK09_HUMAN,tr|E9PQN2|E9PQN2_HUMAN" 7 1166.7023 2.47 1320 11043 2 1166.7011 584.3584 Bcl-2-associated transcription factor 1 OS=Homo sapiens OX=9606 GN=BCLAF1 PE=1 SV=2 8.76 2645.1 - 75074.8 - - - -1.0363 - 1.385 0.134 - 117.7 1 2 0 -0.0012 11 0 0 0 3.50E+07 1.42E+07 - - - 0.9114 0.9997 221125_WJC_METTL3_EV_vs_WT_F01.11046.11046.2 0.00354 14-Oct R.LGMGLVSR[166.11].S "sp|Q8N6H7|ARFG2_HUMAN,tr|E9PIY6|E9PIY6_HUMAN,tr|E9PQP3|E9PQP3_HUMAN,tr|G5E9L0|G5E9L0_HUMAN,tr|A0A0D9SF70|A0A0D9SF70_HUMAN" 5 841.4719 1.09 1321 11046 2 841.471029 421.7432 ADP-ribosylation factor GTPase-activating protein 2 OS=Homo sapiens OX=9606 GN=ARFGAP2 PE=1 SV=1 9.75 2645.6 - 1.35E+06 - - - -1.0684 - 2.016 0.369 - 314 1 2 0 -0.0009 8 0 0 0 1.54E+08 1.42E+08 - - - 3.8807 0.95 221125_WJC_METTL3_EV_vs_WT_F01.11047.11047.2 0.334 12-Jun D.YDIALVR.L sp|P56730|NETR_HUMAN 1 848.4756 2.77 1322 11047 2 848.475537 425.2451 Neurotrypsin OS=Homo sapiens OX=9606 GN=PRSS12 PE=2 SV=2 5.84 2645.7 - 604335 - - - -0.0778 - 1.483 0.297 - 159.6 1 1 0 -0.0001 7 0 0 0 2.42E+07 8.73E+06 - - - 2.4832 0.9994 221125_WJC_METTL3_EV_vs_WT_F01.11050.11050.2 0.0243 14-Jul R.VILPDDVR[166.11].D "sp|Q3YEC7|RABL6_HUMAN,tr|F2Z2T0|F2Z2T0_HUMAN,tr|H0Y7H6|H0Y7H6_HUMAN,tr|G3V154|G3V154_HUMAN" 4 935.5316 0.87 1323 11050 2 935.530953 468.7731 Rab-like protein 6 OS=Homo sapiens OX=9606 GN=RABL6 PE=1 SV=2 4.21 2646.1 - 521184 - - - -0.6403 - 1.425 0.381 - 165.1 1 2 0 -0.0006 8 0 0 0 1.21E+07 1.39E+07 - - - 2.923 0.9997 221125_WJC_METTL3_EV_vs_WT_F01.11052.11052.3 0.00206 16/40 R.LLASTLVHSVK.K "sp|Q9NYF8|BCLF1_HUMAN,tr|E9PKI6|E9PKI6_HUMAN,tr|A0A1W2PQ43|A0A1W2PQ43_HUMAN,tr|E9PK91|E9PK91_HUMAN,tr|E9PJA7|E9PJA7_HUMAN,tr|E9PK09|E9PK09_HUMAN,tr|E9PQN2|E9PQN2_HUMAN" 7 1166.7023 2.07 1324 11052 3 1166.701001 389.908 Bcl-2-associated transcription factor 1 OS=Homo sapiens OX=9606 GN=BCLAF1 PE=1 SV=2 8.76 2646.3 - 760804 - - - -1.1211 - 2.672 0.256 - 214 1 2 0 -0.0013 11 0 0 0 1.20E+08 5.77E+07 - - - 4.1858 0.9996 221125_WJC_METTL3_EV_vs_WT_F01.11056.11056.2 0.327 18-Nov K.YEELQITAGR.H "sp|P04264|K2C1_HUMAN,sp|P04259|K2C6B_HUMAN" 2 1178.5932 2.07 1326 11056 2 1178.592717 590.3039 "Keratin, type II cytoskeletal 1 OS=Homo sapiens OX=9606 GN=KRT1 PE=1 SV=6" 4.53 2646.7 - 180027 - - - -0.3691 - 2.109 0.28 - 493.9 1 2 0 -0.0004 10 0 0 0 1.78E+07 8.58E+06 - - - 3.1919 0.9785 221125_WJC_METTL3_EV_vs_WT_F01.11058.11058.2 0.0109 16-Oct N.LVIITAGAR[166.11].Q "sp|Q9BYZ2|LDH6B_HUMAN,sp|Q6ZMR3|LDH6A_HUMAN,sp|P00338|LDHA_HUMAN,tr|A0A087WUM2|A0A087WUM2_HUMAN,tr|F5GXH2|F5GXH2_HUMAN,tr|F5GYU2|F5GYU2_HUMAN,tr|F5GXY2|F5GXY2_HUMAN" 7 922.5839 1.11 1328 11058 2 922.583939 462.2992 L-lactate dehydrogenase A-like 6B OS=Homo sapiens OX=9606 GN=LDHAL6B PE=1 SV=3 9.75 2647 - 1.23E+06 - - - 0.0184 - 2.015 0.309 - 377.5 1 1 0 0 9 0 0 0 1.37E+08 1.24E+08 - - - 3.3502 0.9997 221125_WJC_METTL3_EV_vs_WT_F01.11065.11065.3 0.00472 14/40 R.LLASTLVHSVK[136.11].K "sp|Q9NYF8|BCLF1_HUMAN,tr|E9PKI6|E9PKI6_HUMAN,tr|A0A1W2PQ43|A0A1W2PQ43_HUMAN,tr|E9PK91|E9PK91_HUMAN,tr|E9PJA7|E9PJA7_HUMAN,tr|E9PK09|E9PK09_HUMAN,tr|E9PQN2|E9PQN2_HUMAN" 7 1174.7165 2.07 1333 11065 3 1174.714954 392.5794 Bcl-2-associated transcription factor 1 OS=Homo sapiens OX=9606 GN=BCLAF1 PE=1 SV=2 8.76 2647.9 - 1.09E+06 - - - -1.3237 - 2.637 0.285 - 150.5 1 2 0 -0.0016 11 0 0 0 1.19E+08 5.76E+07 - - - 4.4716 0.9524 221125_WJC_METTL3_EV_vs_WT_F01.11067.11067.2 0.0622 16-Sep N.LVIITAGAR.Q "sp|Q9BYZ2|LDH6B_HUMAN,sp|Q6ZMR3|LDH6A_HUMAN,sp|P00338|LDHA_HUMAN,tr|A0A087WUM2|A0A087WUM2_HUMAN,tr|F5GXH2|F5GXH2_HUMAN,tr|F5GYU2|F5GYU2_HUMAN,tr|F5GXY2|F5GXY2_HUMAN" 7 912.5757 1.11 1335 11067 2 912.575067 457.2951 L-lactate dehydrogenase A-like 6B OS=Homo sapiens OX=9606 GN=LDHAL6B PE=1 SV=3 9.75 2648.1 - 1.89E+06 - - - -0.641 - 1.805 0.249 - 295.9 1 1 0 -0.0006 9 0 0 0 1.37E+08 1.24E+08 - - - 2.5885 0.996 221125_WJC_METTL3_EV_vs_WT_F01.11068.11068.2 0.074 12-Jul K.VFSPVIR.S "sp|Q96RK0|CIC_HUMAN,tr|A0A0A0MQR4|A0A0A0MQR4_HUMAN,tr|I3L2J0|I3L2J0_HUMAN,tr|A0A7P0T9K5|A0A7P0T9K5_HUMAN" 4 816.4858 0.03 1336 11068 2 816.485293 409.2502 Protein capicua homolog OS=Homo sapiens OX=9606 GN=CIC PE=1 SV=2 9.72 2648.3 - 360456 - - - -0.5891 - 1.32 0.186 - 129.9 1 2 0 -0.0005 7 0 0 0 8.48E+06 2.73E+08 - - - 1.2943 0.9894 221125_WJC_METTL3_EV_vs_WT_F01.11069.11069.2 2.63 14-Jun R.IGLETSLR[166.11].Y sp|Q9Y230|RUVB2_HUMAN 1 897.5159 1.01 1337 11069 2 897.514144 449.7652 RuvB-like 2 OS=Homo sapiens OX=9606 GN=RUVBL2 PE=1 SV=3 6 2648.4 - 218437 - - - -1.9587 - 1.296 0.172 - 81.3 1 2 0 -0.0018 8 0 0 0 1.45E+07 1.44E+07 - - - 1.0928 0.9817 221125_WJC_METTL3_EV_vs_WT_F01.11079.11079.2 2.08 14-May R.VYVSGLMK[136.11].G "sp|Q9HDC9|APMAP_HUMAN,tr|H0Y512|H0Y512_HUMAN" 2 903.4979 0.87 1342 11079 2 903.498168 452.7562 Adipocyte plasma membrane-associated protein OS=Homo sapiens OX=9606 GN=APMAP PE=1 SV=2 8.56 2649.8 - 227216 - - - 0.269 - 0.911 0.2 - 73.1 1 2 0 0.0002 8 0 0 0 9.10E+06 1.04E+07 - - - 0.237 0.998 221125_WJC_METTL3_EV_vs_WT_F01.11083.11083.2 0.0226 14-Jul R.MVLVGDVK[136.11].D "sp|P60891|PRPS1_HUMAN,sp|P11908|PRPS2_HUMAN,tr|A0A2R8Y7H4|A0A2R8Y7H4_HUMAN,tr|B1ALA9|B1ALA9_HUMAN,tr|A0A6Q8PEU0|A0A6Q8PEU0_HUMAN,tr|A0A6Q8PHI4|A0A6Q8PHI4_HUMAN,tr|A0A6Q8PG82|A0A6Q8PG82_HUMAN" 7 867.4979 0.81 1344 11083 2 867.496182 434.7562 Ribose-phosphate pyrophosphokinase 1 OS=Homo sapiens OX=9606 GN=PRPS1 PE=1 SV=2 5.59 2650.2 - 1.26E+06 - - - -2.0092 - 1.606 0.27 - 200.6 1 2 0 -0.0017 8 0 0 0 1.47E+08 1.82E+08 - - - 2.4635 0.9781 221125_WJC_METTL3_EV_vs_WT_F01.11084.11084.2 4.65 14-Jun R.MVLVGDVK.D "sp|P60891|PRPS1_HUMAN,sp|P11908|PRPS2_HUMAN,tr|A0A2R8Y7H4|A0A2R8Y7H4_HUMAN,tr|B1ALA9|B1ALA9_HUMAN,tr|A0A6Q8PEU0|A0A6Q8PEU0_HUMAN,tr|A0A6Q8PHI4|A0A6Q8PHI4_HUMAN,tr|A0A6Q8PG82|A0A6Q8PG82_HUMAN" 7 859.4837 0.81 1345 11084 2 859.483245 430.7491 Ribose-phosphate pyrophosphokinase 1 OS=Homo sapiens OX=9606 GN=PRPS1 PE=1 SV=2 5.59 2650.3 - 696155 - - - -0.5585 - 1.227 0.063 - 136.6 1 2 0 -0.0005 8 0 0 0 1.47E+08 1.82E+08 - - - 0.1231 0.988 221125_WJC_METTL3_EV_vs_WT_F01.11090.11090.2 0.889 14-Jul K.LINAVELK.K sp|P56192|SYMC_HUMAN 1 898.5488 0.81 1349 11090 2 898.548362 450.2817 "Methionine--tRNA ligase, cytoplasmic OS=Homo sapiens OX=9606 GN=MARS1 PE=1 SV=2" 6 2651.1 - 373761 - - - -0.4518 - 1.212 0.12 - 85.8 1 2 0 -0.0004 8 0 0 0 1.34E+08 1.65E+08 - - - 0.5071 0.9752 221125_WJC_METTL3_EV_vs_WT_F01.11092.11092.2 0.435 12-Jul K.IIVDELK[136.11].Q "sp|P63244|RACK1_HUMAN,tr|H0YAM7|H0YAM7_HUMAN,tr|H0YAF8|H0YAF8_HUMAN,tr|H0Y9P0|H0Y9P0_HUMAN,tr|D6RF23|D6RF23_HUMAN,tr|J3KPE3|J3KPE3_HUMAN,tr|D6RAC2|D6RAC2_HUMAN,tr|D6REE5|D6REE5_HUMAN,tr|H0Y8W2|H0Y8W2_HUMAN" 9 836.5099 1.03 1350 11092 2 836.508962 419.2622 Receptor of activated protein C kinase 1 OS=Homo sapiens OX=9606 GN=RACK1 PE=1 SV=3 4.37 2651.3 - 2.27E+06 - - - -1.0855 - 1.429 0.016 - 142.4 2 2 0 -0.0009 7 0 0 0 3.21E+08 3.11E+08 - - - 0.1555 0.8664 221125_WJC_METTL3_EV_vs_WT_F01.11094.11094.2 0.0168 16-Jun L.ASTLVHSVK.K "sp|Q9NYF8|BCLF1_HUMAN,tr|E9PKI6|E9PKI6_HUMAN,tr|A0A1W2PQ43|A0A1W2PQ43_HUMAN,tr|E9PK91|E9PK91_HUMAN,tr|E9PJA7|E9PJA7_HUMAN,tr|E9PK09|E9PK09_HUMAN,tr|E9PQN2|E9PQN2_HUMAN" 7 940.5342 2.33 1352 11094 2 940.535207 471.2744 Bcl-2-associated transcription factor 1 OS=Homo sapiens OX=9606 GN=BCLAF1 PE=1 SV=2 8.8 2651.5 - 226375 - - - 1.0909 - 1.461 0.261 - 110.6 3 1 0 0.001 9 0 0 0 5.98E+06 2.56E+06 - - - 1.8521 0.9999 221125_WJC_METTL3_EV_vs_WT_F01.11104.11104.2 2.54E-05 12-Aug K.C[160.03]PVFVVR.W "sp|Q9C0J8|WDR33_HUMAN,tr|C9J8B4|C9J8B4_HUMAN" 2 875.4687 1.84 1355 11104 2 875.468324 438.7416 pre-mRNA 3' end processing protein WDR33 OS=Homo sapiens OX=9606 GN=WDR33 PE=1 SV=2 8.25 2652.9 - 611239 - - - -0.4797 - 1.818 0.538 - 349.7 1 2 0 -0.0004 7 0 0 0 4.25E+07 2.31E+07 - - - 4.9085 0.9995 221125_WJC_METTL3_EV_vs_WT_F01.11108.11108.2 0.0175 14-Sep R.LLGQIVDR.C sp|Q96I24|FUBP3_HUMAN 1 912.5393 1.72 1357 11108 2 912.538021 457.2769 Far upstream element-binding protein 3 OS=Homo sapiens OX=9606 GN=FUBP3 PE=1 SV=2 5.84 2653.5 - 6.18E+06 - - - -1.3643 - 1.606 0.392 - 227 1 2 0 -0.0012 8 0 0 0 1.93E+09 1.13E+09 - - - 3.3647 0.9984 221125_WJC_METTL3_EV_vs_WT_F01.11109.11109.2 0.0499 14-Sep R.LLGQIVDR[166.11].C sp|Q96I24|FUBP3_HUMAN 1 922.5475 1.72 1358 11109 2 922.546043 462.281 Far upstream element-binding protein 3 OS=Homo sapiens OX=9606 GN=FUBP3 PE=1 SV=2 5.84 2653.5 - 5.25E+06 - - - -1.6183 - 1.674 0.244 - 231.8 1 2 0 -0.0015 8 0 0 0 1.93E+09 1.12E+09 - - - 2.3966 0.9661 221125_WJC_METTL3_EV_vs_WT_F01.11117.11117.2 4.41 14-Jun R.LVSLIGSK.T "sp|P25786|PSA1_HUMAN,tr|F5GX11|F5GX11_HUMAN" 2 815.5117 0.72 1362 11117 2 815.510465 408.7631 Proteasome subunit alpha type-1 OS=Homo sapiens OX=9606 GN=PSMA1 PE=1 SV=1 8.75 2654.6 - 290279 - - - -1.458 - 1.174 0.075 - 78.3 1 2 0 -0.0012 8 0 0 0 1.02E+07 1.42E+07 - - - 0.0784 0.9821 221125_WJC_METTL3_EV_vs_WT_F01.11133.11133.2 0.921 12-Aug K.LGLQSLR[166.11].N "sp|P18085|ARF4_HUMAN,tr|C9JAK5|C9JAK5_HUMAN,tr|U3KQF2|U3KQF2_HUMAN" 3 795.4842 0.92 1368 11133 2 795.481812 398.7494 ADP-ribosylation factor 4 OS=Homo sapiens OX=9606 GN=ARF4 PE=1 SV=3 9.75 2656.8 - 2.06E+06 - - - -3.012 - 1.556 0.111 - 176.5 1 2 0 -0.0024 7 0 0 0 1.66E+08 1.81E+08 - - - 1.261 0.9925 221125_WJC_METTL3_EV_vs_WT_F01.11134.11134.2 0.0756 12-Jun K.LGLQSLR.N "sp|P18085|ARF4_HUMAN,tr|C9JAK5|C9JAK5_HUMAN,tr|U3KQF2|U3KQF2_HUMAN" 3 785.4759 0.92 1369 11134 2 785.474019 393.7452 ADP-ribosylation factor 4 OS=Homo sapiens OX=9606 GN=ARF4 PE=1 SV=3 9.75 2656.9 - 1.25E+06 - - - -2.4431 - 1.549 0.159 - 93.4 1 2 0 -0.0019 7 0 0 0 1.66E+08 1.82E+08 - - - 1.6014 0.9865 221125_WJC_METTL3_EV_vs_WT_F01.11154.11154.2 2.14 16-Jun R.LILENHAAK[136.11].L "sp|Q9ULL1|PKHG1_HUMAN,tr|H0YD71|H0YD71_HUMAN" 2 1015.5906 0 1376 11154 2 1015.589825 508.8026 Pleckstrin homology domain-containing family G member 1 OS=Homo sapiens OX=9606 GN=PLEKHG1 PE=1 SV=2 6.75 2659.7 - 455509 - - - -0.7434 - 1.277 0.098 - 73.5 1 2 0 -0.0008 9 0 0 0 3.89E+04 1.13E+08 - - - 0.472 0.9941 221125_WJC_METTL3_EV_vs_WT_F01.11167.11167.2 0.0208 12-Jul R.VFVVMEK.L "sp|Q15139|KPCD1_HUMAN,sp|O94806|KPCD3_HUMAN,sp|Q9BZL6|KPCD2_HUMAN,tr|M0R2Z8|M0R2Z8_HUMAN,tr|F8WBA3|F8WBA3_HUMAN" 5 850.4623 0.13 1381 11167 2 850.460493 426.2384 Serine\threonine-protein kinase D1 OS=Homo sapiens OX=9606 GN=PRKD1 PE=1 SV=2 5.97 2661.5 - 191764 - - - -2.0789 - 1.381 0.207 - 165.2 1 2 0 -0.0018 7 0 0 0 9.16E+06 6.95E+07 - - - 1.5922 0.998 221125_WJC_METTL3_EV_vs_WT_F01.11177.11177.2 0.0326 16-Jul R.LLPAELPAK[136.11].R sp|P78527|PRKDC_HUMAN 1 958.5943 4.43 1384 11177 2 958.592326 480.3044 DNA-dependent protein kinase catalytic subunit OS=Homo sapiens OX=9606 GN=PRKDC PE=1 SV=3 6 2662.9 - 471717 - - - -2.0259 - 1.665 0.281 - 128.5 2 2 0 -0.0019 9 0 0 0 1.09E+08 2.46E+07 - - - 2.4563 0.9954 221125_WJC_METTL3_EV_vs_WT_F01.11189.11189.2 0.385 12-Jun R.IILEEVR.E sp|P37287|PIGA_HUMAN 1 870.5175 0.24 1388 11189 2 870.517404 436.266 Phosphatidylinositol N-acetylglucosaminyltransferase subunit A OS=Homo sapiens OX=9606 GN=PIGA PE=1 SV=1 4.53 2664.6 - 227631 - - - -0.0735 - 1.416 0.138 - 125.6 1 2 0 -0.0001 7 0 0 0 5.95E+06 2.43E+07 - - - 1.1624 0.999 221125_WJC_METTL3_EV_vs_WT_F01.11223.11223.2 0.0145 20-Jun K.LLAETVAPAVR[166.11].G "sp|Q9BSJ8|ESYT1_HUMAN,tr|F8VZB1|F8VZB1_HUMAN" 2 1148.6793 1 1403 11223 2 1148.678491 575.3469 Extended synaptotagmin-1 OS=Homo sapiens OX=9606 GN=ESYT1 PE=1 SV=1 6 2669.4 - 159034 - - - -0.686 - 1.533 0.308 - 92.5 1 2 0 -0.0008 11 0 0 0 1.86E+07 1.86E+07 - - - 2.4714 0.9994 221125_WJC_METTL3_EV_vs_WT_F01.11227.11227.2 0.00952 16-Aug R.DYQELMNTK.L sp|P04264|K2C1_HUMAN 1 1140.5121 999 1404 11227 2 1140.511388 571.2633 "Keratin, type II cytoskeletal 1 OS=Homo sapiens OX=9606 GN=KRT1 PE=1 SV=6" 4.37 2669.9 - 457302 - - - -0.6462 - 1.256 0.443 - 211.6 1 2 0 -0.0007 9 0 0 0 9.29E+07 0.00E+00 - - - 2.9722 0.9774 221125_WJC_METTL3_EV_vs_WT_F01.11237.11237.2 0.313 12-May R.VVVEYLR.A sp|O60645|EXOC3_HUMAN 1 876.5069 0.94 1408 11237 2 876.504948 439.2607 Exocyst complex component 3 OS=Homo sapiens OX=9606 GN=EXOC3 PE=1 SV=3 5.97 2671.2 - 422668 - - - -2.2304 - 0.976 0.234 - 107.4 1 2 0 -0.002 7 0 0 0 2.54E+07 2.71E+07 - - - 0.6917 0.9987 221125_WJC_METTL3_EV_vs_WT_F01.11239.11239.2 0.137 16-Jul K.NDLAVVDVR[166.11].L "sp|P19338|NUCL_HUMAN,tr|A0A7I2V506|A0A7I2V506_HUMAN,tr|A0A7I2V699|A0A7I2V699_HUMAN,tr|A0A7I2V2U7|A0A7I2V2U7_HUMAN,tr|A0A7I2V3F3|A0A7I2V3F3_HUMAN,tr|A0A7I2V428|A0A7I2V428_HUMAN,tr|A0A7I2V349|A0A7I2V349_HUMAN,tr|H7BY16|H7BY16_HUMAN,tr|A0A7I2V5M5|A0A7I2V5M5_HUMAN,tr|A0A7I2V2S8|A0A7I2V2S8_HUMAN,tr|C9JLB1|C9JLB1_HUMAN" 11 1009.5432 0.72 1410 11239 2 1009.54238 505.7789 Nucleolin OS=Homo sapiens OX=9606 GN=NCL PE=1 SV=3 4.21 2671.4 - 134092 - - - -0.7914 - 1.488 0.276 - 187.4 1 2 0 -0.0008 9 0 0 0 5.47E+06 7.62E+06 - - - 2.2291 0.9969 221125_WJC_METTL3_EV_vs_WT_F01.11251.11251.2 0.00183 16-Jul R.AGAAAILIR[166.11].D sp|Q5T440|CAF17_HUMAN 1 864.5421 1.51 1415 11251 2 864.540986 433.2783 "Putative transferase CAF17, mitochondrial OS=Homo sapiens OX=9606 GN=IBA57 PE=1 SV=1" 9.79 2672.9 - 215197 - - - -1.2388 - 1.72 0.144 - 159.6 1 2 0 -0.0011 9 0 0 0 1.28E+07 8.50E+06 - - - 1.6732 0.9996 221125_WJC_METTL3_EV_vs_WT_F01.11256.11256.2 0.00285 16-Jul K.NDLAVVDVR.L "sp|P19338|NUCL_HUMAN,tr|A0A7I2V506|A0A7I2V506_HUMAN,tr|A0A7I2V699|A0A7I2V699_HUMAN,tr|A0A7I2V2U7|A0A7I2V2U7_HUMAN,tr|A0A7I2V3F3|A0A7I2V3F3_HUMAN,tr|A0A7I2V428|A0A7I2V428_HUMAN,tr|A0A7I2V349|A0A7I2V349_HUMAN,tr|H7BY16|H7BY16_HUMAN,tr|A0A7I2V5M5|A0A7I2V5M5_HUMAN,tr|A0A7I2V2S8|A0A7I2V2S8_HUMAN,tr|C9JLB1|C9JLB1_HUMAN" 11 999.5349 0.77 1418 11256 2 999.53351 500.7747 Nucleolin OS=Homo sapiens OX=9606 GN=NCL PE=1 SV=3 4.21 2673.5 - 246376 - - - -1.3997 - 1.676 0.412 - 202.3 1 2 0 -0.0014 9 0 0 0 5.32E+06 6.88E+06 - - - 3.5776 0.9882 221125_WJC_METTL3_EV_vs_WT_F01.11262.11262.2 1.43 12-Oct R.VVVEYLR[166.11].A sp|O60645|EXOC3_HUMAN 1 886.5152 1.14 1421 11262 2 886.512781 444.2649 Exocyst complex component 3 OS=Homo sapiens OX=9606 GN=EXOC3 PE=1 SV=3 5.97 2674.3 - 687860 - - - -2.6982 - 1.394 0.177 - 461.5 1 2 0 -0.0024 7 0 0 0 2.33E+07 2.04E+07 - - - 1.4001 0.7975 221125_WJC_METTL3_EV_vs_WT_F01.11269.11269.2 0.111 14-Jul D.GGLNLYTR[166.11].S "sp|Q8IVL0|NAV3_HUMAN,tr|A0A2R8YFX5|A0A2R8YFX5_HUMAN" 2 902.4849 1.15 1423 11269 2 902.482901 452.2497 Neuron navigator 3 OS=Homo sapiens OX=9606 GN=NAV3 PE=1 SV=3 8.75 2675.2 - 320383 - - - -2.2549 - 1.381 0.263 - 246.7 1 1 0 -0.002 8 0 0 0 5.62E+07 4.90E+07 - - - 1.9565 0.8583 221125_WJC_METTL3_EV_vs_WT_F01.11270.11270.2 0.00393 22-Sep W.ELISNASDALDK.L "sp|Q58FF8|H90B2_HUMAN,sp|P08238|HS90B_HUMAN,sp|Q58FF6|H90B4_HUMAN,sp|Q58FF7|H90B3_HUMAN,sp|P14625|ENPL_HUMAN,tr|A0A7P0T917|A0A7P0T917_HUMAN,tr|A0A7P0Z405|A0A7P0Z405_HUMAN,tr|A0A7P0T823|A0A7P0T823_HUMAN,tr|A0A7P0TAE1|A0A7P0TAE1_HUMAN,tr|H0YIV0|H0YIV0_HUMAN,tr|A0A7P0T8R3|A0A7P0T8R3_HUMAN,tr|A0A7P0T885|A0A7P0T885_HUMAN,tr|A0A7P0TAY2|A0A7P0TAY2_HUMAN,tr|A0A087WT78|A0A087WT78_HUMAN,tr|F8W026|F8W026_HUMAN,tr|A0A7P0TBC2|A0A7P0TBC2_HUMAN,tr|A0A7P0TAT8|A0A7P0TAT8_HUMAN" 17 1274.6354 130.1 1424 11270 2 1274.631833 638.325 Putative heat shock protein HSP 90-beta 2 OS=Homo sapiens OX=9606 GN=HSP90AB2P PE=1 SV=2 4.03 2675.3 - 263520 - - - -2.8071 - 1.5 0.349 - 201 1 1 0 -0.0036 12 0 0 0 1.38E+07 1.06E+05 - - - 2.6844 0.96 221125_WJC_METTL3_EV_vs_WT_F01.11274.11274.2 1.81 12-Jun K.LDPVLYR[166.11].K "sp|Q92896|GSLG1_HUMAN,tr|H3BM42|H3BM42_HUMAN" 2 884.4995 1.23 1426 11274 2 884.499333 443.257 Golgi apparatus protein 1 OS=Homo sapiens OX=9606 GN=GLG1 PE=1 SV=2 5.84 2675.9 - 648936 - - - -0.2148 - 1.121 0.041 - 190.8 1 2 0 -0.0002 7 0 0 0 1.28E+08 1.04E+08 - - - -0.2943 0.9741 221125_WJC_METTL3_EV_vs_WT_F01.11276.11276.2 2.71 12-Jun K.FLEATLR.S "sp|Q9NXS2|QPCTL_HUMAN,tr|A0A7I2V5X1|A0A7I2V5X1_HUMAN" 2 848.4756 0.82 1427 11276 2 848.476853 425.2451 Glutaminyl-peptide cyclotransferase-like protein OS=Homo sapiens OX=9606 GN=QPCTL PE=1 SV=2 6 2676.1 - 460512 - - - 1.4732 - 1.329 0.052 - 127.1 1 2 0 0.0013 7 0 0 0 2.15E+07 2.64E+07 - - - 0.3259 0.9993 221125_WJC_METTL3_EV_vs_WT_F01.11278.11278.2 0.0141 14-Jul R.ILDAPEIR[166.11].N sp|Q12834|CDC20_HUMAN 1 935.5316 1.69 1428 11278 2 935.530648 468.7731 Cell division cycle protein 20 homolog OS=Homo sapiens OX=9606 GN=CDC20 PE=1 SV=2 4.37 2676.3 - 168112 - - - -0.9663 - 1.63 0.317 - 139.1 1 2 0 -0.0009 8 0 0 0 1.45E+07 8.57E+06 - - - 2.8556 0.9822 221125_WJC_METTL3_EV_vs_WT_F01.11280.11280.2 0.0178 16-Oct K.VGLQVVAVK[136.11].A "sp|P10809|CH60_HUMAN,tr|A0A7I2V2X6|A0A7I2V2X6_HUMAN,tr|A0A7I2YQK6|A0A7I2YQK6_HUMAN,tr|A0A7I2V599|A0A7I2V599_HUMAN,tr|A0A7I2V5M1|A0A7I2V5M1_HUMAN" 5 919.5946 1.2 1429 11280 2 919.589945 460.8046 "60 kDa heat shock protein, mitochondrial OS=Homo sapiens OX=9606 GN=HSPD1 PE=1 SV=2" 8.72 2676.6 - 625566 - - - -5.0653 - 1.965 0.199 - 255.1 1 2 0 -0.0047 9 0 0 0 2.25E+08 1.87E+08 - - - 2.4636 0.9897 221125_WJC_METTL3_EV_vs_WT_F01.11286.11286.2 1.22 12-Jun R.LGLTEIR.K "sp|Q8WWY3|PRP31_HUMAN,tr|E7EVX8|E7EVX8_HUMAN" 2 800.4756 2.36 1432 11286 2 800.473864 401.2451 U4\U6 small nuclear ribonucleoprotein Prp31 OS=Homo sapiens OX=9606 GN=PRPF31 PE=1 SV=2 6 2677.3 - 5.54E+06 - - - -2.1725 - 1.542 0.109 - 110.7 1 2 0 -0.0017 7 0 0 0 1.20E+09 5.09E+08 - - - 1.2178 0.9991 221125_WJC_METTL3_EV_vs_WT_F01.11291.11291.2 0.741 16-Nov K.VGLQVVAVK.A "sp|P10809|CH60_HUMAN,tr|A0A7I2V2X6|A0A7I2V2X6_HUMAN,tr|A0A7I2YQK6|A0A7I2YQK6_HUMAN,tr|A0A7I2V599|A0A7I2V599_HUMAN,tr|A0A7I2V5M1|A0A7I2V5M1_HUMAN" 5 911.5804 1.2 1434 11291 2 911.578312 456.7975 "60 kDa heat shock protein, mitochondrial OS=Homo sapiens OX=9606 GN=HSPD1 PE=1 SV=2" 8.72 2677.9 - 990856 - - - -2.2938 - 2.156 0.298 - 374.2 1 2 0 -0.0021 9 0 0 0 2.25E+08 1.87E+08 - - - 3.464 0.9848 221125_WJC_METTL3_EV_vs_WT_F01.11294.11294.2 1.31 12-Sep K.LEDLIVK.D "sp|P24752|THIL_HUMAN,tr|A0A5F9ZHJ7|A0A5F9ZHJ7_HUMAN,tr|A0A5F9ZHD4|A0A5F9ZHD4_HUMAN,tr|A0A5F9ZHH9|A0A5F9ZHH9_HUMAN,tr|A0A5F9ZHJ0|A0A5F9ZHJ0_HUMAN,tr|A0A5F9ZHL1|A0A5F9ZHL1_HUMAN,tr|A0A5F9ZI66|A0A5F9ZI66_HUMAN,tr|H0YEL7|H0YEL7_HUMAN" 8 828.4957 1.23 1436 11294 2 828.492682 415.2551 "Acetyl-CoA acetyltransferase, mitochondrial OS=Homo sapiens OX=9606 GN=ACAT1 PE=1 SV=1" 4.37 2678.2 - 3.61E+07 - - - -3.6065 - 1.734 0.126 - 269.7 1 2 0 -0.003 7 0 0 0 1.60E+09 1.29E+09 - - - 1.7148 0.9923 221125_WJC_METTL3_EV_vs_WT_F01.11298.11298.2 0.269 14-Jul R.ILDAPEIR.N sp|Q12834|CDC20_HUMAN 1 925.5233 1.69 1438 11298 2 925.520525 463.7689 Cell division cycle protein 20 homolog OS=Homo sapiens OX=9606 GN=CDC20 PE=1 SV=2 4.37 2678.6 - 239565 - - - -2.9789 - 1.496 0.222 - 115.9 1 2 0 -0.0028 8 0 0 0 1.49E+07 8.83E+06 - - - 1.8946 0.9916 221125_WJC_METTL3_EV_vs_WT_F01.11319.11319.2 1.11 12-Sep K.LEDLIVK[136.11].D "sp|P24752|THIL_HUMAN,tr|A0A5F9ZHJ7|A0A5F9ZHJ7_HUMAN,tr|A0A5F9ZHD4|A0A5F9ZHD4_HUMAN,tr|A0A5F9ZHH9|A0A5F9ZHH9_HUMAN,tr|A0A5F9ZHJ0|A0A5F9ZHJ0_HUMAN,tr|A0A5F9ZHL1|A0A5F9ZHL1_HUMAN,tr|A0A5F9ZI66|A0A5F9ZI66_HUMAN,tr|H0YEL7|H0YEL7_HUMAN" 8 836.5099 1.23 1447 11319 2 836.506934 419.2622 "Acetyl-CoA acetyltransferase, mitochondrial OS=Homo sapiens OX=9606 GN=ACAT1 PE=1 SV=1" 4.37 2681.4 - 2.63E+07 - - - -3.5098 - 1.992 0.124 - 265.6 1 2 0 -0.0029 7 0 0 0 1.60E+09 1.29E+09 - - - 2.1395 0.9908 221125_WJC_METTL3_EV_vs_WT_F01.11337.11337.2 1.65 12-Jul R.LGLTEIR[166.11].K "sp|Q8WWY3|PRP31_HUMAN,tr|E7EVX8|E7EVX8_HUMAN" 2 810.4839 2.36 1454 11337 2 810.481762 406.2492 U4\U6 small nuclear ribonucleoprotein Prp31 OS=Homo sapiens OX=9606 GN=PRPF31 PE=1 SV=2 6 2683.7 - 1.35E+07 - - - -2.6046 - 1.611 0.134 - 148.8 1 2 0 -0.0021 7 0 0 0 1.20E+09 5.09E+08 - - - 1.541 0.8844 221125_WJC_METTL3_EV_vs_WT_F01.11348.11348.2 0.84 16-May R.VIMAELATK[136.11].N "sp|Q9HAN9|NMNA1_HUMAN,tr|B1AN62|B1AN62_HUMAN" 2 982.5613 30.21 1461 11348 2 982.563973 492.2879 Nicotinamide\nicotinic acid mononucleotide adenylyltransferase 1 OS=Homo sapiens OX=9606 GN=NMNAT1 PE=1 SV=1 5.97 2685 - 134141 - - - 2.7673 - 0.921 0.141 - 45.7 1 2 0 0.0027 9 0 0 0 1.40E+08 4.64E+06 - - - -0.1565 0.9946 221125_WJC_METTL3_EV_vs_WT_F01.11349.11349.2 0.399 14-Aug R.ALLGPALK[136.11].D sp|P35250|RFC2_HUMAN 1 789.5204 0.83 1462 11349 2 789.519518 395.7675 Replication factor C subunit 2 OS=Homo sapiens OX=9606 GN=RFC2 PE=1 SV=3 8.8 2685.2 - 602042 - - - -1.0855 - 1.429 0.147 - 184.3 1 2 0 -0.0009 8 0 0 0 4.43E+07 5.30E+07 - - - 1.2031 0.9964 221125_WJC_METTL3_EV_vs_WT_F01.11358.11358.2 0.0587 14-Sep R.ALLGPALK.D sp|P35250|RFC2_HUMAN 1 781.5062 0.83 1467 11358 2 781.504025 391.7604 Replication factor C subunit 2 OS=Homo sapiens OX=9606 GN=RFC2 PE=1 SV=3 8.8 2686.4 - 704667 - - - -2.7511 - 1.713 0.234 - 241.3 1 2 0 -0.0022 8 0 0 0 4.44E+07 5.33E+07 - - - 2.392 0.9481 221125_WJC_METTL3_EV_vs_WT_F01.11373.11373.2 0.0593 12-Jun K.LDPVLYR.K "sp|Q92896|GSLG1_HUMAN,tr|H3BM42|H3BM42_HUMAN" 2 874.4913 1.23 1474 11373 2 874.490203 438.2529 Golgi apparatus protein 1 OS=Homo sapiens OX=9606 GN=GLG1 PE=1 SV=2 5.84 2688.4 - 507133 - - - -1.2007 - 1.223 0.004 - 168.3 1 2 0 -0.001 7 0 0 0 1.28E+08 1.04E+08 - - - -0.2919 1 221125_WJC_METTL3_EV_vs_WT_F01.11386.11386.3 5.68E-11 13/68 K.YVHYEIDAC[160.03]MDSEAPGSK[136.11].D "sp|Q86U44|MTA70_HUMAN,tr|H0YFV6|H0YFV6_HUMAN" 2 2078.8805 0.001 1482 11386 3 2078.881818 693.9674 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 4.31 2690 - 124738 - - - 0.6378 - 2.59 0.736 - 175.6 1 2 0 0.0013 18 0 0 0 0.00E+00 4.50E+06 - - - 9.115 0.9874 221125_WJC_METTL3_EV_vs_WT_F01.11392.11392.2 0.243 14-Aug R.IGLAEEIR.H "sp|Q13085|ACACA_HUMAN,tr|Q59FY4|Q59FY4_HUMAN" 2 899.5076 0.66 1486 11392 2 899.503245 450.7611 Acetyl-CoA carboxylase 1 OS=Homo sapiens OX=9606 GN=ACACA PE=1 SV=2 4.53 2690.7 - 220094 - - - -4.8771 - 1.609 0.296 - 183.2 1 2 0 -0.0044 8 0 0 0 4.25E+06 6.43E+06 - - - 2.6603 0.9947 221125_WJC_METTL3_EV_vs_WT_F01.11397.11397.2 1.18E-07 Sep-32 N.IVSNASC[160.03]TTNC[160.03]LAPLAK.V "sp|O14556|G3PT_HUMAN,tr|K7EP73|K7EP73_HUMAN" 2 1818.8968 999 1489 11397 2 1818.895992 910.4557 "Glyceraldehyde-3-phosphate dehydrogenase, testis-specific OS=Homo sapiens OX=9606 GN=GAPDHS PE=1 SV=2" 8.06 2691.4 - 118062 - - - -0.447 - 1.969 0.652 - 150.9 1 1 0 -0.0008 17 0 0 0 9.66E+06 0.00E+00 - - - 5.5221 0.9993 221125_WJC_METTL3_EV_vs_WT_F01.11426.11426.2 0.0357 14-Aug K.LIEQYALR.E sp|Q9NUQ3|TXLNG_HUMAN 1 1004.5655 1.01 1506 11426 2 1004.564655 503.29 Gamma-taxilin OS=Homo sapiens OX=9606 GN=TXLNG PE=1 SV=2 6 2695.2 - 861321 - - - -0.8222 - 1.723 0.281 - 227.2 1 2 0 -0.0008 8 0 0 0 4.69E+07 4.63E+07 - - - 2.7571 0.9662 221125_WJC_METTL3_EV_vs_WT_F01.11427.11427.2 0.448 12-Jul K.ILLVDER[166.11].S "sp|A5YKK6|CNOT1_HUMAN,tr|H3BMZ2|H3BMZ2_HUMAN" 2 866.5101 0.66 1507 11427 2 866.506008 434.2623 CCR4-NOT transcription complex subunit 1 OS=Homo sapiens OX=9606 GN=CNOT1 PE=1 SV=2 4.37 2695.3 - 753295 - - - -4.7085 - 1.563 0.169 - 172 1 2 0 -0.0041 7 0 0 0 2.01E+07 3.04E+07 - - - 1.7031 0.9029 221125_WJC_METTL3_EV_vs_WT_F01.11432.11432.2 9.56 12-Jul R.YPDPLIK[136.11].V "sp|P62701|RS4X_HUMAN,sp|Q8TD47|RS4Y2_HUMAN" 2 852.4837 2.33 1510 11432 2 852.482126 427.2491 "40S ribosomal protein S4, X isoform OS=Homo sapiens OX=9606 GN=RPS4X PE=1 SV=2" 5.83 2696 - 523501 - - - -1.7936 - 1.125 0.013 - 143.8 1 2 0 -0.0015 7 0 0 0 3.95E+08 1.69E+08 - - - -0.4903 0.9906 221125_WJC_METTL3_EV_vs_WT_F01.11433.11433.2 0.0438 12-Jun R.YPDPLIK.V "sp|P62701|RS4X_HUMAN,sp|Q8TD47|RS4Y2_HUMAN" 2 844.4695 1.47 1511 11433 2 844.468348 423.242 "40S ribosomal protein S4, X isoform OS=Homo sapiens OX=9606 GN=RPS4X PE=1 SV=2" 5.83 2696.1 - 590731 - - - -1.3109 - 1.37 0.115 - 122.6 1 2 0 -0.0011 7 0 0 0 2.16E+09 1.47E+09 - - - 0.8875 0.9085 221125_WJC_METTL3_EV_vs_WT_F01.11437.11437.2 0.147 12-Jun K.GLVLMSR[166.11].A "sp|P27824|CALX_HUMAN,tr|A0A7P0T937|A0A7P0T937_HUMAN,tr|A0A7P0T840|A0A7P0T840_HUMAN,tr|D6RFL1|D6RFL1_HUMAN,tr|A0A7P0Z4H2|A0A7P0Z4H2_HUMAN,tr|A0A7P0TB65|A0A7P0TB65_HUMAN,tr|A0A7P0TAN9|A0A7P0TAN9_HUMAN,tr|A0A7P0TAE9|A0A7P0TAE9_HUMAN,tr|A0A7P0T8N1|A0A7P0T8N1_HUMAN,tr|D6RGY2|D6RGY2_HUMAN,tr|A0A7P0T8G1|A0A7P0T8G1_HUMAN,tr|A0A7P0Z4D6|A0A7P0Z4D6_HUMAN,tr|A0A7P0Z484|A0A7P0Z484_HUMAN,tr|A0A7P0TAR9|A0A7P0TAR9_HUMAN,tr|A0A7P0T9L0|A0A7P0T9L0_HUMAN,tr|D6RAU8|D6RAU8_HUMAN" 16 784.4505 1.14 1513 11437 2 784.449113 393.2325 Calnexin OS=Homo sapiens OX=9606 GN=CANX PE=1 SV=2 9.75 2696.6 - 1.25E+06 - - - -1.7235 - 1.164 0 - 181.1 1 2 0 -0.0014 7 0 0 0 5.96E+08 5.21E+08 - - - -0.4782 0.7832 221125_WJC_METTL3_EV_vs_WT_F01.11438.11438.2 0.136 18-Sep R.IVATKPLYVA.L "sp|Q9H361|PABP3_HUMAN,sp|P11940|PABP1_HUMAN,tr|A0A7I2YQE4|A0A7I2YQE4_HUMAN,tr|A0A7I2V649|A0A7I2V649_HUMAN,tr|H0YB86|H0YB86_HUMAN,tr|H0YAR2|H0YAR2_HUMAN,tr|E7ERJ7|E7ERJ7_HUMAN,tr|A0A7I2YQ88|A0A7I2YQ88_HUMAN,tr|A0A087WTT1|A0A087WTT1_HUMAN,tr|A0A7I2YQ90|A0A7I2YQ90_HUMAN,tr|A0A7I2V4N4|A0A7I2V4N4_HUMAN,tr|E7EQV3|E7EQV3_HUMAN" 12 1073.6485 1.34 1514 11438 2 1073.650357 537.8315 Polyadenylate-binding protein 3 OS=Homo sapiens OX=9606 GN=PABPC3 PE=1 SV=2 8.59 2696.7 - 610898 - - - 1.7464 - 1.19 0.291 - 151.6 1 1 0 0.0019 10 0 0 0 1.77E+08 1.32E+08 - - - 1.6753 0.9383 221125_WJC_METTL3_EV_vs_WT_F01.11453.11453.2 1.13 20-Jun R.DLARPGAAHLR.V tr|F8WEC8|F8WEC8_HUMAN 1 1175.6523 999 1520 11453 2 1175.652031 588.8334 Mitochondrial-processing peptidase subunit beta OS=Homo sapiens OX=9606 GN=PMPCB PE=4 SV=1 9.61 2698.8 - 605329 - - - -0.262 - 0.941 0.103 - 54 3 2 0 -0.0003 11 0 0 0 5.66E+07 0.00E+00 - - - -0.576 0.9986 221125_WJC_METTL3_EV_vs_WT_F01.11459.11459.2 0.565 12-Sep K.LTELLVK.A "sp|O95470|SGPL1_HUMAN,tr|H0Y3V8|H0Y3V8_HUMAN,tr|H7BXL7|H7BXL7_HUMAN" 3 814.5164 1.8 1523 11459 2 814.515107 408.2655 Sphingosine-1-phosphate lyase 1 OS=Homo sapiens OX=9606 GN=SGPL1 PE=1 SV=3 6 2699.6 - 667932 - - - -1.5936 - 1.871 0.201 - 247.8 1 2 0 -0.0013 7 0 0 0 4.07E+07 2.27E+07 - - - 2.5102 0.9885 221125_WJC_METTL3_EV_vs_WT_F01.11462.11462.2 2.31 12-Sep K.IDPLLPK.E sp|Q9BYD6|RM01_HUMAN 1 794.4902 3.42 1524 11462 2 794.488339 398.2524 "39S ribosomal protein L1, mitochondrial OS=Homo sapiens OX=9606 GN=MRPL1 PE=1 SV=2" 5.84 2700 - 1.27E+06 - - - -2.3311 - 1.44 0.168 - 215.9 3 2 0 -0.0019 7 0 0 0 2.06E+08 6.02E+07 - - - 1.2235 0.995 221125_WJC_METTL3_EV_vs_WT_F01.11463.11463.2 0.717 12-Aug K.FVNLYTR[166.11].E "sp|Q15650|TRIP4_HUMAN,tr|H0YL91|H0YL91_HUMAN" 2 921.4948 1.25 1525 11463 2 921.494358 461.7547 Activating signal cointegrator 1 OS=Homo sapiens OX=9606 GN=TRIP4 PE=1 SV=4 8.75 2700.1 - 297065 - - - -0.4493 - 1.413 0.133 - 235.6 1 2 0 -0.0004 7 0 0 0 1.68E+07 1.35E+07 - - - 1.1186 0.998 221125_WJC_METTL3_EV_vs_WT_F01.11470.11470.2 0.104 12-Aug K.VPVNLLR[166.11].A "sp|Q14204|DYHC1_HUMAN,tr|A0A7P0T8N2|A0A7P0T8N2_HUMAN,tr|A0A7P0T9C4|A0A7P0T9C4_HUMAN,tr|A0A7P0TBJ7|A0A7P0TBJ7_HUMAN,tr|A0A2R8Y706|A0A2R8Y706_HUMAN,tr|A0A7P0T916|A0A7P0T916_HUMAN,tr|A0A7P0TAW9|A0A7P0TAW9_HUMAN,tr|A0A7P0TA13|A0A7P0TA13_HUMAN,tr|A0A7P0T7V5|A0A7P0T7V5_HUMAN,tr|A0A7P0T9R4|A0A7P0T9R4_HUMAN,tr|A0A2R8Y5T0|A0A2R8Y5T0_HUMAN" 11 819.5206 0.92 1528 11470 2 819.518916 410.7676 Cytoplasmic dynein 1 heavy chain 1 OS=Homo sapiens OX=9606 GN=DYNC1H1 PE=1 SV=5 9.72 2701 - 497990 - - - -2.0463 - 1.623 0.256 - 347.4 1 2 0 -0.0017 7 0 0 0 5.02E+07 5.46E+07 - - - 2.4657 0.9989 221125_WJC_METTL3_EV_vs_WT_F01.11473.11473.2 0.0369 16-Aug R.LITGLGVGR.E sp|Q9BQG0|MBB1A_HUMAN 1 884.5444 0.84 1529 11473 2 884.543511 443.2795 Myb-binding protein 1A OS=Homo sapiens OX=9606 GN=MYBBP1A PE=1 SV=2 9.75 2701.4 - 478795 - - - -0.9496 - 1.327 0.351 - 144.9 1 2 0 -0.0008 9 0 0 0 3.95E+07 4.72E+07 - - - 2.4517 0.9868 221125_WJC_METTL3_EV_vs_WT_F01.11474.11474.2 0.0727 12-Jul R.AAYIYIR[166.11].G "sp|P49821|NDUV1_HUMAN,tr|G3V0I5|G3V0I5_HUMAN,tr|B4DE93|B4DE93_HUMAN,tr|E9PJL9|E9PJL9_HUMAN,tr|E9PPR0|E9PPR0_HUMAN,tr|E9PLC6|E9PLC6_HUMAN,tr|E9PMX3|E9PMX3_HUMAN,tr|E9PQP1|E9PQP1_HUMAN" 8 878.489 1.1 1530 11474 2 878.485388 440.2518 "NADH dehydrogenase [ubiquinone] flavoprotein 1, mitochondrial OS=Homo sapiens OX=9606 GN=NDUFV1 PE=1 SV=4" 8.63 2701.5 - 498140 - - - -4.0649 - 1.546 0.228 - 192.7 1 2 0 -0.0036 7 0 0 0 2.40E+07 2.19E+07 - - - 2.1043 0.9965 221125_WJC_METTL3_EV_vs_WT_F01.11477.11477.2 0.434 12-Aug K.IDPLLPK[136.11].E sp|Q9BYD6|RM01_HUMAN 1 802.5044 3.43 1531 11477 2 802.502795 402.2595 "39S ribosomal protein L1, mitochondrial OS=Homo sapiens OX=9606 GN=MRPL1 PE=1 SV=2" 5.84 2701.9 - 795623 - - - -1.9888 - 1.464 0.232 - 226.9 1 2 0 -0.0016 7 0 0 0 2.06E+08 6.02E+07 - - - 1.9618 0.9354 221125_WJC_METTL3_EV_vs_WT_F01.11533.11533.2 0.0107 16-Aug H.LLDPDVVAR[166.11].F sp|Q86U44|MTA70_HUMAN 1 1006.5687 0.02 1555 11533 2 1006.570813 504.2916 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 4.21 2709.2 - 604597 - - - 2.134 - 1.495 0.395 - 166.4 1 1 0 0.0021 9 0 0 0 5.69E+07 2.45E+09 - - - 3.1212 0.9998 221125_WJC_METTL3_EV_vs_WT_F01.11537.11537.2 8.51E-05 Nov-32 R.ISIGGGSC[160.03]AISGGYGSR.A "sp|P48668|K2C6C_HUMAN,sp|P04259|K2C6B_HUMAN,sp|P02538|K2C6A_HUMAN" 3 1597.7519 999 1558 11537 2 1597.754805 799.8832 "Keratin, type II cytoskeletal 6C OS=Homo sapiens OX=9606 GN=KRT6C PE=1 SV=3" 8.22 2709.7 - 96634.8 - - - 1.8463 - 2.48 0.601 - 298.2 1 2 0 0.0029 17 0 0 0 4.14E+06 0.00E+00 - - - 5.7121 0.9991 221125_WJC_METTL3_EV_vs_WT_F01.11547.11547.2 0.0154 14-Aug K.ILVDALQK.F "sp|O75787|RENR_HUMAN,tr|B7Z413|B7Z413_HUMAN,tr|A0A1B0GTU8|A0A1B0GTU8_HUMAN,tr|A0A1B0GVI9|A0A1B0GVI9_HUMAN,tr|B7Z1I9|B7Z1I9_HUMAN,tr|A0A1B0GVC7|A0A1B0GVC7_HUMAN,tr|H7C3E1|H7C3E1_HUMAN,tr|A0A1B0GUT7|A0A1B0GUT7_HUMAN,tr|A0A1B0GU12|A0A1B0GU12_HUMAN,tr|A0A1C7CYW4|A0A1C7CYW4_HUMAN,tr|A0A1B0GWD6|A0A1B0GWD6_HUMAN,tr|A0A1B0GVB9|A0A1B0GVB9_HUMAN,tr|A0A1B0GWJ8|A0A1B0GWJ8_HUMAN,tr|A0A1B0GVW0|A0A1B0GVW0_HUMAN,tr|A0A1B0GTB0|A0A1B0GTB0_HUMAN" 15 898.5488 1.13 1561 11547 2 898.549214 450.2817 Renin receptor OS=Homo sapiens OX=9606 GN=ATP6AP2 PE=1 SV=2 5.84 2711.3 - 1.23E+06 - - - 0.4964 - 1.601 0.277 - 159.2 1 2 0 0.0004 8 0 0 0 4.78E+07 4.22E+07 - - - 2.5062 0.9948 221125_WJC_METTL3_EV_vs_WT_F01.11548.11548.2 0.429 14-Jul R.LAAQFIPK.F "sp|Q9BZZ5|API5_HUMAN,tr|E9PQK6|E9PQK6_HUMAN,tr|G3V1C3|G3V1C3_HUMAN" 3 886.5276 1.94 1562 11548 2 886.527376 444.2711 Apoptosis inhibitor 5 OS=Homo sapiens OX=9606 GN=API5 PE=1 SV=3 8.75 2711.4 - 435971 - - - -0.2967 - 1.295 0.169 - 110.9 1 2 0 -0.0003 8 0 0 0 3.36E+07 1.73E+07 - - - 1.0688 0.988 221125_WJC_METTL3_EV_vs_WT_F01.11550.11550.2 0.046 12-Jul K.GLVLMSR.A "sp|P27824|CALX_HUMAN,tr|A0A7P0T937|A0A7P0T937_HUMAN,tr|A0A7P0T840|A0A7P0T840_HUMAN,tr|D6RFL1|D6RFL1_HUMAN,tr|A0A7P0Z4H2|A0A7P0Z4H2_HUMAN,tr|A0A7P0TB65|A0A7P0TB65_HUMAN,tr|A0A7P0TAN9|A0A7P0TAN9_HUMAN,tr|A0A7P0TAE9|A0A7P0TAE9_HUMAN,tr|A0A7P0T8N1|A0A7P0T8N1_HUMAN,tr|D6RGY2|D6RGY2_HUMAN,tr|A0A7P0T8G1|A0A7P0T8G1_HUMAN,tr|A0A7P0Z4D6|A0A7P0Z4D6_HUMAN,tr|A0A7P0Z484|A0A7P0Z484_HUMAN,tr|A0A7P0TAR9|A0A7P0TAR9_HUMAN,tr|A0A7P0T9L0|A0A7P0T9L0_HUMAN,tr|D6RAU8|D6RAU8_HUMAN" 16 774.4422 1.13 1563 11550 2 774.442321 388.2284 Calnexin OS=Homo sapiens OX=9606 GN=CANX PE=1 SV=2 9.75 2711.6 - 1.44E+06 - - - 0.1627 - 1.589 0 - 312.1 1 2 0 0.0001 7 0 0 0 5.87E+08 5.20E+08 - - - 0.5083 0.9985 221125_WJC_METTL3_EV_vs_WT_F01.11554.11554.2 0.0531 24-Sep R.GGIGAGLGGGLC[160.03]R.R "sp|Q9NXV2|KCTD5_HUMAN,tr|H3BSS5|H3BSS5_HUMAN" 2 1143.5819 4.29 1565 11554 2 1143.58012 572.7982 BTB\POZ domain-containing protein KCTD5 OS=Homo sapiens OX=9606 GN=KCTD5 PE=1 SV=1 8.25 2712.1 - 346608 - - - -1.5355 - 1.728 0.269 - 156 1 2 0 -0.0018 13 0 0 0 6.14E+06 1.43E+06 - - - 2.4311 0.9234 221125_WJC_METTL3_EV_vs_WT_F01.11563.11563.2 0.0154 14-Jul R.LLASTLVH.S "sp|Q9NYF8|BCLF1_HUMAN,tr|E9PKI6|E9PKI6_HUMAN,tr|A0A1W2PQ43|A0A1W2PQ43_HUMAN,tr|E9PK91|E9PK91_HUMAN,tr|E9PJA7|E9PJA7_HUMAN,tr|E9PK09|E9PK09_HUMAN,tr|E9PQN2|E9PQN2_HUMAN" 7 852.5069 - 1569 11563 2 852.50617 427.2607 Bcl-2-associated transcription factor 1 OS=Homo sapiens OX=9606 GN=BCLAF1 PE=1 SV=2 6.74 2713.3 - 4.18E+06 - - - -0.8598 - 1.169 0.364 - 140.3 1 1 0 -0.0007 8 0 0 0 - - - - - 2.2002 0.9752 221125_WJC_METTL3_EV_vs_WT_F01.11582.11582.2 1.85 12-Jun R.ILLYAC[160.03]R[166.11].N "sp|P36954|RPB9_HUMAN,tr|K7EKS1|K7EKS1_HUMAN" 2 917.5032 1.27 1579 11582 2 917.501973 459.7589 DNA-directed RNA polymerase II subunit RPB9 OS=Homo sapiens OX=9606 GN=POLR2I PE=1 SV=1 8.22 2715.8 - 738348 - - - -1.3689 - 1.152 0.103 - 133.4 1 2 0 -0.0013 7 0 0 0 6.09E+07 4.78E+07 - - - 0.2497 0.9932 221125_WJC_METTL3_EV_vs_WT_F01.11585.11585.2 0.269 14-Jul R.LLEEGVLR.Q "sp|Q6P996|PDXD1_HUMAN,tr|H3BND4|H3BND4_HUMAN" 2 927.5389 1.43 1582 11585 2 927.536309 464.7767 Pyridoxal-dependent decarboxylase domain-containing protein 1 OS=Homo sapiens OX=9606 GN=PDXDC1 PE=1 SV=2 4.53 2716.2 - 151426 - - - -2.8279 - 1.386 0.255 - 131.2 1 2 0 -0.0026 8 0 0 0 1.36E+08 9.49E+07 - - - 1.9081 0.9917 221125_WJC_METTL3_EV_vs_WT_F01.11593.11593.2 0.501 12-Jul R.ILLYAC[160.03]R.N "sp|P36954|RPB9_HUMAN,tr|K7EKS1|K7EKS1_HUMAN" 2 907.495 1.28 1586 11593 2 907.493456 454.7548 DNA-directed RNA polymerase II subunit RPB9 OS=Homo sapiens OX=9606 GN=POLR2I PE=1 SV=1 8.22 2717.1 - 1.11E+06 - - - -1.6562 - 1.357 0.151 - 168.3 1 2 0 -0.0015 7 0 0 0 6.09E+07 4.78E+07 - - - 1.1231 0.825 221125_WJC_METTL3_EV_vs_WT_F01.11601.11601.2 0.012 12-Jun L.GNFGEVR.L "sp|P48067|SC6A9_HUMAN,tr|J3KPA5|J3KPA5_HUMAN,tr|B7Z3A9|B7Z3A9_HUMAN,tr|B7Z589|B7Z589_HUMAN" 4 777.377 2.88 1590 11601 2 777.374498 389.6958 Sodium- and chloride-dependent glycine transporter 1 OS=Homo sapiens OX=9606 GN=SLC6A9 PE=1 SV=3 6 2718.2 - 1.90E+06 - - - -3.1568 - 1.346 0.367 - 166.1 1 1 0 -0.0025 7 0 0 0 1.27E+08 4.40E+07 - - - 2.6924 0.9747 221125_WJC_METTL3_EV_vs_WT_F01.11604.11604.2 2.75 14-Jul R.TFGVSPLR.R sp|Q5T750|XP32_HUMAN 1 875.4865 14.3 1591 11604 2 875.486689 438.7505 Skin-specific protein 32 OS=Homo sapiens OX=9606 GN=XP32 PE=1 SV=1 9.41 2718.6 - 752108 - - - 0.2136 - 1.177 0.066 - 132 1 2 0 0.0002 8 0 0 0 5.54E+07 3.88E+06 - - - 0.0199 0.9123 221125_WJC_METTL3_EV_vs_WT_F01.11607.11607.2 0.114 16-Sep H.LLDPDVVAR.F sp|Q86U44|MTA70_HUMAN 1 996.5604 0.02 1593 11607 2 996.558414 499.2875 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 4.21 2718.9 - 618130 - - - -1.9878 - 1.747 0.268 - 264.1 1 1 0 -0.002 9 0 0 0 5.07E+07 2.43E+09 - - - 2.6339 0.7788 221125_WJC_METTL3_EV_vs_WT_F01.11611.11611.2 0.537 12-Aug K.IAIYLSK.S "sp|Q9H583|HEAT1_HUMAN,tr|Q5T3Q7|Q5T3Q7_HUMAN" 2 806.4902 0.34 1595 11611 2 806.484681 404.2524 HEAT repeat-containing protein 1 OS=Homo sapiens OX=9606 GN=HEATR1 PE=1 SV=3 8.59 2719.5 - 210486 - - - -6.8321 - 1.736 0.061 - 194.8 1 2 0 -0.0055 7 0 0 0 7.90E+06 2.29E+07 - - - 1.2375 0.9917 221125_WJC_METTL3_EV_vs_WT_F01.11615.11615.2 0.689 12-Jul K.IPVIIER.Y "sp|A6NCE7|MP3B2_HUMAN,sp|Q9GZQ8|MLP3B_HUMAN,sp|Q9H492|MLP3A_HUMAN,tr|H3BTL1|H3BTL1_HUMAN" 4 838.5276 1.35 1597 11615 2 838.525686 420.2711 Microtubule-associated proteins 1A\1B light chain 3 beta 2 OS=Homo sapiens OX=9606 GN=MAP1LC3B2 PE=2 SV=1 6 2720 - 570568 - - - -2.3291 - 1.431 0.174 - 205.3 1 2 0 -0.002 7 0 0 0 5.56E+07 4.11E+07 - - - 1.4611 0.9442 221125_WJC_METTL3_EV_vs_WT_F01.11616.11616.2 2.93 14-Jun R.LLEEGVLR[166.11].Q "sp|Q6P996|PDXD1_HUMAN,tr|H3BND4|H3BND4_HUMAN" 2 937.5472 1.43 1598 11616 2 937.545048 469.7809 Pyridoxal-dependent decarboxylase domain-containing protein 1 OS=Homo sapiens OX=9606 GN=PDXDC1 PE=1 SV=2 4.53 2720.1 - 1.71E+06 - - - -2.2975 - 1.217 0.093 - 102.3 3 2 0 -0.0022 8 0 0 0 1.36E+08 9.49E+07 - - - 0.1064 0.7885 221125_WJC_METTL3_EV_vs_WT_F01.11630.11630.2 12.8 14-May R.VFVSPLAK[136.11].K "sp|P10515|ODP2_HUMAN,tr|A0A7P0TBE2|A0A7P0TBE2_HUMAN,tr|A0A7P0Z4G4|A0A7P0Z4G4_HUMAN,tr|A0A7P0TAX2|A0A7P0TAX2_HUMAN,tr|A0A7P0TBK2|A0A7P0TBK2_HUMAN,tr|E9PEJ4|E9PEJ4_HUMAN,tr|A0A7P0TAG1|A0A7P0TAG1_HUMAN,tr|A0A7P0TA47|A0A7P0TA47_HUMAN,tr|A0A7P0T997|A0A7P0T997_HUMAN,tr|H0YDD4|H0YDD4_HUMAN" 10 867.5309 0.97 1602 11630 2 867.528113 434.7727 "Dihydrolipoyllysine-residue acetyltransferase component of pyruvate dehydrogenase complex, mitochondrial OS=Homo sapiens OX=9606 GN=DLAT PE=1 SV=3" 8.72 2722 - 3.85E+06 - - - -3.2587 - 1.158 0.063 - 63.6 6 2 0 -0.0028 8 0 0 0 1.64E+08 1.69E+08 - - - -0.3997 0.9995 221125_WJC_METTL3_EV_vs_WT_F01.11634.11634.2 0.000405 24-Nov R.FSGSGSGTDFTLK.L "sp|A2NJV5|KV229_HUMAN,sp|A0A087WW87|KV240_HUMAN,sp|P06310|KV230_HUMAN,sp|A0A075B6S2|KVD29_HUMAN,sp|P01614|KVD40_HUMAN,sp|P01615|KVD28_HUMAN,sp|A0A075B6S6|KVD30_HUMAN,sp|A0A075B6P5|KV228_HUMAN,sp|A0A0A0MRZ7|KVD26_HUMAN" 9 1302.6092 29994.34 1603 11634 2 1302.60573 652.3119 Immunoglobulin kappa variable 2-29 OS=Homo sapiens OX=9606 GN=IGKV2-29 PE=3 SV=2 5.84 2722.6 - 2.00E+06 - - - -2.6608 - 1.997 0.523 - 224.3 1 2 0 -0.0035 13 0 0 0 1.90E+09 6.33E+04 - - - 4.6779 0.7751 221125_WJC_METTL3_EV_vs_WT_F01.11640.11640.2 0.0378 14-Jun K.LLDVVHPA.A "sp|Q99832|TCPH_HUMAN,tr|F8WAM2|F8WAM2_HUMAN" 2 862.4913 - 1604 11640 2 862.488548 432.2529 T-complex protein 1 subunit eta OS=Homo sapiens OX=9606 GN=CCT7 PE=1 SV=2 5.08 2723.5 - 2.74E+06 - - - -3.1363 - 1.336 0.354 - 73.9 2 1 0 -0.0027 8 0 0 0 - - - - - 2.394 0.9805 221125_WJC_METTL3_EV_vs_WT_F01.11644.11644.2 0.617 12-Jun K.LSIVPVR.R "sp|P15880|RS2_HUMAN,tr|I3L404|I3L404_HUMAN,tr|E9PM36|E9PM36_HUMAN,tr|E9PPT0|E9PPT0_HUMAN,tr|E9PMM9|E9PMM9_HUMAN,tr|H0YEN5|H0YEN5_HUMAN" 6 782.5014 1 1605 11644 2 782.499354 392.258 40S ribosomal protein S2 OS=Homo sapiens OX=9606 GN=RPS2 PE=1 SV=2 9.75 2724.1 - 4.14E+06 - - - -2.6454 - 1.389 0.125 - 105 1 2 0 -0.0021 7 0 0 0 5.28E+08 5.27E+08 - - - 1.0047 0.9975 221125_WJC_METTL3_EV_vs_WT_F01.11646.11646.2 0.0258 16-Jul K.LVPVGYGIK.K sp|P24534|EF1B_HUMAN 1 944.5695 0.78 1607 11646 2 944.570395 473.292 Elongation factor 1-beta OS=Homo sapiens OX=9606 GN=EEF1B2 PE=1 SV=3 8.59 2724.3 - 313834 - - - 0.9433 - 1.364 0.273 - 143.2 2 2 0 0.0009 9 0 0 0 7.18E+08 9.26E+08 - - - 1.8207 0.9917 221125_WJC_METTL3_EV_vs_WT_F01.11648.11648.2 0.0888 14-Jul R.VFVSPLAK.K "sp|P10515|ODP2_HUMAN,tr|A0A7P0TBE2|A0A7P0TBE2_HUMAN,tr|A0A7P0Z4G4|A0A7P0Z4G4_HUMAN,tr|A0A7P0TAX2|A0A7P0TAX2_HUMAN,tr|A0A7P0TBK2|A0A7P0TBK2_HUMAN,tr|E9PEJ4|E9PEJ4_HUMAN,tr|A0A7P0TAG1|A0A7P0TAG1_HUMAN,tr|A0A7P0TA47|A0A7P0TA47_HUMAN,tr|A0A7P0T997|A0A7P0T997_HUMAN,tr|H0YDD4|H0YDD4_HUMAN" 10 859.5167 0.97 1608 11648 2 859.514488 430.7656 "Dihydrolipoyllysine-residue acetyltransferase component of pyruvate dehydrogenase complex, mitochondrial OS=Homo sapiens OX=9606 GN=DLAT PE=1 SV=3" 8.72 2724.6 - 2.54E+06 - - - -2.6201 - 1.25 0.259 - 189.1 1 2 0 -0.0023 8 0 0 0 1.64E+08 1.68E+08 - - - 1.6263 0.9998 221125_WJC_METTL3_EV_vs_WT_F01.11652.11652.2 0.000112 20-Nov R.NPEAALSPTFR[166.11].S "sp|Q86U44|MTA70_HUMAN,tr|B4E349|B4E349_HUMAN,tr|F5H6D8|F5H6D8_HUMAN,tr|B4DTN4|B4DTN4_HUMAN" 4 1211.6174 0.02 1611 11652 2 1211.614918 606.816 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 6 2724.9 - 1.59E+06 - - - -2.0543 - 2.431 0.529 - 533.7 1 2 0 -0.0025 11 0 0 0 9.07E+07 3.89E+09 - - - 5.3505 0.9996 221125_WJC_METTL3_EV_vs_WT_F01.11653.11653.2 0.00211 16-Aug K.LVPVGYGIK[136.11].K sp|P24534|EF1B_HUMAN 1 952.5837 0.78 1612 11653 2 952.584058 477.2991 Elongation factor 1-beta OS=Homo sapiens OX=9606 GN=EEF1B2 PE=1 SV=3 8.59 2725.1 - 670246 - - - 0.3716 - 1.546 0.419 - 246 1 2 0 0.0004 9 0 0 0 7.18E+08 9.26E+08 - - - 3.396 0.9927 221125_WJC_METTL3_EV_vs_WT_F01.11663.11663.2 0.0709 12-Jun R.YPDPLIK.V "sp|P62701|RS4X_HUMAN,sp|Q8TD47|RS4Y2_HUMAN" 2 844.4695 1.47 1617 11663 2 844.467716 423.242 "40S ribosomal protein S4, X isoform OS=Homo sapiens OX=9606 GN=RPS4X PE=1 SV=2" 5.83 2726.4 - 1.39E+07 - - - -2.0593 - 1.078 0.289 - 101.4 1 2 0 -0.0017 7 0 0 0 2.16E+09 1.47E+09 - - - 1.413 0.9993 221125_WJC_METTL3_EV_vs_WT_F01.11665.11665.2 0.00351 16-Sep R.NVIEAVYSR.L "sp|O75688|PPM1B_HUMAN,tr|B8ZZF0|B8ZZF0_HUMAN,tr|A0A3B3IS24|A0A3B3IS24_HUMAN,tr|C9JIR6|C9JIR6_HUMAN" 4 1049.5506 4.04 1618 11665 2 1049.549801 525.7826 Protein phosphatase 1B OS=Homo sapiens OX=9606 GN=PPM1B PE=1 SV=1 6 2726.6 - 310199 - - - -0.7222 - 1.453 0.353 - 268.4 1 2 0 -0.0008 9 0 0 0 3.14E+07 7.78E+06 - - - 2.729 0.9979 221125_WJC_METTL3_EV_vs_WT_F01.11679.11679.2 0.0111 12-Sep R.YPDPLIK[136.11].V "sp|P62701|RS4X_HUMAN,sp|Q8TD47|RS4Y2_HUMAN" 2 852.4837 1.36 1624 11679 2 852.481597 427.2491 "40S ribosomal protein S4, X isoform OS=Homo sapiens OX=9606 GN=RPS4X PE=1 SV=2" 5.83 2728.4 - 1.23E+07 - - - -2.4141 - 1.493 0.321 - 234.3 1 2 0 -0.0021 7 0 0 0 1.80E+09 1.32E+09 - - - 2.6812 0.999 221125_WJC_METTL3_EV_vs_WT_F01.11686.11686.2 0.00985 14-Aug R.LYDAYELK.H "sp|P08758|ANXA5_HUMAN,tr|E9PHT9|E9PHT9_HUMAN,tr|D6RBL5|D6RBL5_HUMAN" 3 1013.507 1.2 1627 11686 2 1013.506352 507.7608 Annexin A5 OS=Homo sapiens OX=9606 GN=ANXA5 PE=1 SV=2 4.37 2729.4 - 309998 - - - -0.6029 - 1.368 0.324 - 131.4 1 2 0 -0.0006 8 0 0 0 1.43E+07 1.19E+07 - - - 2.3789 0.9966 221125_WJC_METTL3_EV_vs_WT_F01.11689.11689.2 0.0139 12-Jul K.LMELYER[166.11].L "sp|Q9UG63|ABCF2_HUMAN,tr|C9JZV3|C9JZV3_HUMAN,tr|C9JHK9|C9JHK9_HUMAN" 3 962.4771 0.56 1628 11689 2 962.474174 482.2458 ATP-binding cassette sub-family F member 2 OS=Homo sapiens OX=9606 GN=ABCF2 PE=1 SV=2 4.53 2729.8 - 2.06E+06 - - - -3.012 - 1.552 0.295 - 221.4 1 2 0 -0.0029 7 0 0 0 4.91E+07 8.82E+07 - - - 2.6117 0.9998 221125_WJC_METTL3_EV_vs_WT_F01.11700.11700.3 0.000817 Nov-40 R.NPEAALSPTFR[166.11].S "sp|Q86U44|MTA70_HUMAN,tr|B4E349|B4E349_HUMAN,tr|F5H6D8|F5H6D8_HUMAN,tr|B4DTN4|B4DTN4_HUMAN" 4 1211.6174 0.02 1632 11700 3 1211.613655 404.8797 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 6 2731.3 - 2.12E+06 - - - -3.0967 - 2.436 0.436 - 275.5 1 2 0 -0.0038 11 0 0 0 3.73E+06 2.29E+08 - - - 5.9293 0.9877 221125_WJC_METTL3_EV_vs_WT_F01.11704.11704.2 0.439 16-Jul R.LSESQLSFR.R sp|Q96PK6|RBM14_HUMAN 1 1065.5455 1.98 1634 11704 2 1065.542273 533.78 RNA-binding protein 14 OS=Homo sapiens OX=9606 GN=RBM14 PE=1 SV=2 6 2731.7 - 377062 - - - -3.0041 - 1.293 0.238 - 131.2 1 2 0 -0.0032 9 0 0 0 8.90E+06 4.50E+06 - - - 1.5413 0.9961 221125_WJC_METTL3_EV_vs_WT_F01.11707.11707.2 0.154 14-Aug K.LLEYSGLK.K sp|A8K2U0|A2ML1_HUMAN 1 921.5171 61.42 1635 11707 2 921.515576 461.7658 Alpha-2-macroglobulin-like protein 1 OS=Homo sapiens OX=9606 GN=A2ML1 PE=1 SV=3 6 2732.1 - 403642 - - - -1.6907 - 1.377 0.23 - 162.5 1 2 0 -0.0016 8 0 0 0 4.78E+07 7.78E+05 - - - 1.7041 0.9997 221125_WJC_METTL3_EV_vs_WT_F01.11714.11714.2 0.00156 20-Aug R.NPEAALSPTFR.S "sp|Q86U44|MTA70_HUMAN,tr|B4E349|B4E349_HUMAN,tr|F5H6D8|F5H6D8_HUMAN,tr|B4DTN4|B4DTN4_HUMAN" 4 1201.6091 0.02 1638 11714 2 1201.606767 601.8118 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 6 2733 - 1.18E+06 - - - -1.9724 - 2.024 0.461 - 98.5 1 2 0 -0.0024 11 0 0 0 9.07E+07 3.89E+09 - - - 4.3526 0.9801 221125_WJC_METTL3_EV_vs_WT_F01.11716.11716.2 0.184 12-May K.LSIVPVR[166.11].R "sp|P15880|RS2_HUMAN,tr|I3L404|I3L404_HUMAN,tr|E9PM36|E9PM36_HUMAN,tr|E9PPT0|E9PPT0_HUMAN,tr|E9PMM9|E9PMM9_HUMAN,tr|H0YEN5|H0YEN5_HUMAN" 6 792.5097 1 1640 11716 2 792.507504 397.2621 40S ribosomal protein S2 OS=Homo sapiens OX=9606 GN=RPS2 PE=1 SV=2 9.75 2733.1 - 7.26E+06 - - - -2.7634 - 1.13 0.22 - 55.2 1 2 0 -0.0022 7 0 0 0 5.28E+08 5.27E+08 - - - 1.0525 0.9736 221125_WJC_METTL3_EV_vs_WT_F01.11720.11720.2 2.47 14-May K.AAAISTSR[166.11].V "sp|Q9NVU7|SDA1_HUMAN,tr|E7EW05|E7EW05_HUMAN" 2 785.4271 0.02 1642 11720 2 785.426127 393.7208 Protein SDA1 homolog OS=Homo sapiens OX=9606 GN=SDAD1 PE=1 SV=3 9.79 2733.6 - 8.04E+06 - - - -1.2223 - 1.132 0.137 - 45.5 4 2 0 -0.001 8 0 0 0 8.38E+06 4.71E+08 - - - 0.1576 0.9672 221125_WJC_METTL3_EV_vs_WT_F01.11760.11760.2 0.00143 20-Jul R.TNAENEFVTIK.K sp|P04264|K2C1_HUMAN 1 1264.6299 18.82 1657 11760 2 1264.622233 633.3222 "Keratin, type II cytoskeletal 1 OS=Homo sapiens OX=9606 GN=KRT1 PE=1 SV=6" 4.53 2738.9 - 268653 - - - -6.0879 - 1.671 0.287 - 131.1 1 2 0 -0.0077 11 0 0 0 2.92E+07 1.55E+06 - - - 2.5473 0.9033 221125_WJC_METTL3_EV_vs_WT_F01.11774.11774.2 0.0652 12-Jul T.LVDEVFR.L "sp|P15927|RFA2_HUMAN,tr|Q5TEJ7|Q5TEJ7_HUMAN" 2 876.4705 1.38 1665 11774 2 876.470113 439.2425 Replication protein A 32 kDa subunit OS=Homo sapiens OX=9606 GN=RPA2 PE=1 SV=1 4.37 2740.9 - 243702 - - - -0.4621 - 1.24 0.295 - 119.1 1 1 0 -0.0004 7 0 0 0 2.95E+07 2.14E+07 - - - 1.9013 0.9994 221125_WJC_METTL3_EV_vs_WT_F01.11775.11775.2 0.00879 16-Aug K.VLEGMEVVR.K "sp|P23284|PPIB_HUMAN,tr|A0A7P0Z497|A0A7P0Z497_HUMAN,tr|A0A7P0TB45|A0A7P0TB45_HUMAN" 3 1030.5481 0.39 1666 11775 2 1030.547778 516.2813 Peptidyl-prolyl cis-trans isomerase B OS=Homo sapiens OX=9606 GN=PPIB PE=1 SV=2 4.53 2741 - 183306 - - - -0.328 - 1.687 0.321 - 243.2 1 2 0 -0.0003 9 0 0 0 1.25E+08 3.17E+08 - - - 2.9247 0.8873 221125_WJC_METTL3_EV_vs_WT_F01.11780.11780.2 0.0691 14-Aug R.PLEMIEPR[166.11].T "sp|P62249|RS16_HUMAN,tr|M0R3H0|M0R3H0_HUMAN,tr|M0R1M5|M0R1M5_HUMAN,tr|Q6IPX4|Q6IPX4_HUMAN" 4 993.5193 0.89 1667 11780 2 993.519083 497.7669 40S ribosomal protein S16 OS=Homo sapiens OX=9606 GN=RPS16 PE=1 SV=2 4.53 2741.8 - 142961 - - - -0.1902 - 1.473 0.208 - 262.7 1 1 0 -0.0002 8 0 0 0 2.01E+08 2.26E+08 - - - 1.7453 0.8066 221125_WJC_METTL3_EV_vs_WT_F01.11798.11798.2 0.345 16-May R.YMLEPDPDK[136.11].R "sp|Q2M2I8|AAK1_HUMAN,tr|E9PG46|E9PG46_HUMAN,tr|A0A096LP25|A0A096LP25_HUMAN" 3 1114.5096 0.03 1676 11798 2 1114.51517 558.2621 AP2-associated protein kinase 1 OS=Homo sapiens OX=9606 GN=AAK1 PE=1 SV=3 4.03 2744.2 - 406115 - - - 4.9869 - 0.912 0.233 - 54 1 2 0 0.0056 9 0 0 0 8.79E+05 2.84E+07 - - - 0.4937 0.8103 221125_WJC_METTL3_EV_vs_WT_F01.11831.11831.2 5.13E-05 14-Oct R.PLEMIEPR.T "sp|P62249|RS16_HUMAN,tr|M0R3H0|M0R3H0_HUMAN,tr|M0R1M5|M0R1M5_HUMAN,tr|Q6IPX4|Q6IPX4_HUMAN" 4 983.511 0.9 1684 11831 2 983.505948 492.7628 40S ribosomal protein S16 OS=Homo sapiens OX=9606 GN=RPS16 PE=1 SV=2 4.53 2749 - 2.22E+06 - - - -5.1387 - 2.066 0.403 - 447.8 1 1 0 -0.0051 8 0 0 0 2.03E+08 2.26E+08 - - - 4.2044 0.9908 221125_WJC_METTL3_EV_vs_WT_F01.11848.11848.2 0.189 14-Jul R.EMLAAALR[166.11].T "sp|P23193|TCEA1_HUMAN,tr|A0A1W2PRL9|A0A1W2PRL9_HUMAN,tr|A0A1W2PPZ5|A0A1W2PPZ5_HUMAN" 3 883.4825 5.46 1691 11848 2 883.479637 442.7485 Transcription elongation factor A protein 1 OS=Homo sapiens OX=9606 GN=TCEA1 PE=1 SV=2 6.1 2751.3 - 759821 - - - -3.2327 - 1.422 0.243 - 183.7 1 2 0 -0.0029 8 0 0 0 5.20E+08 9.52E+07 - - - 1.8967 0.9381 221125_WJC_METTL3_EV_vs_WT_F01.11879.11879.2 0.185 12-Jul R.LLSVNIR[166.11].V sp|P07814|SYEP_HUMAN 1 823.5155 0.73 1698 11879 2 823.510999 412.765 Bifunctional glutamate\proline--tRNA ligase OS=Homo sapiens OX=9606 GN=EPRS1 PE=1 SV=5 9.75 2755.7 - 1.11E+06 - - - -5.4753 - 1.47 0.186 - 170.1 1 2 0 -0.0045 7 0 0 0 1.23E+08 1.68E+08 - - - 1.6341 0.9713 221125_WJC_METTL3_EV_vs_WT_F01.11881.11881.2 0.331 14-Aug K.LIGEYGLR.N "sp|P46781|RS9_HUMAN,tr|C9JM19|C9JM19_HUMAN,tr|B5MCT8|B5MCT8_HUMAN,tr|F2Z3C0|F2Z3C0_HUMAN,tr|A8MXK4|A8MXK4_HUMAN" 5 919.5127 0.98 1699 11881 2 919.509492 460.7636 40S ribosomal protein S9 OS=Homo sapiens OX=9606 GN=RPS9 PE=1 SV=3 6 2755.9 - 1.16E+06 - - - -3.5073 - 1.664 0.081 - 173 1 2 0 -0.0032 8 0 0 0 1.65E+09 1.68E+09 - - - 1.1741 0.9439 221125_WJC_METTL3_EV_vs_WT_F01.11886.11886.2 1.03 12-May R.YPDPLIK.V "sp|P62701|RS4X_HUMAN,sp|Q8TD47|RS4Y2_HUMAN" 2 844.4695 1.09 1700 11886 2 844.466782 423.242 "40S ribosomal protein S4, X isoform OS=Homo sapiens OX=9606 GN=RPS4X PE=1 SV=2" 5.83 2756.7 - 5.37E+06 - - - -3.1653 - 1.246 0.124 - 73.6 2 2 0 -0.0027 7 0 0 0 1.43E+09 1.31E+09 - - - 0.5184 0.9112 221125_WJC_METTL3_EV_vs_WT_F01.11887.11887.2 1.91 14-Jun K.IIGDAYLK.Q "sp|Q9Y2H2|SAC2_HUMAN,tr|A0A3B3ISI3|A0A3B3ISI3_HUMAN,tr|A0A3B3IRJ9|A0A3B3IRJ9_HUMAN,tr|A0A3B3ITL0|A0A3B3ITL0_HUMAN,tr|A0A3B3ITR9|A0A3B3ITR9_HUMAN,tr|A0A3B3ISJ5|A0A3B3ISJ5_HUMAN" 6 891.5066 0.57 1701 11887 2 891.503852 446.7606 Phosphatidylinositide phosphatase SAC2 OS=Homo sapiens OX=9606 GN=INPP5F PE=1 SV=3 5.83 2756.8 - 854859 - - - -3.0477 - 1.09 0.15 - 61.7 4 2 0 -0.0027 8 0 0 0 3.37E+07 5.92E+07 - - - 0.139 0.9776 221125_WJC_METTL3_EV_vs_WT_F01.11888.11888.2 0.0137 16-Oct R.PLISVYSEK[136.11].G "sp|P36578|RL4_HUMAN,tr|H3BTP7|H3BTP7_HUMAN,tr|H3BU31|H3BU31_HUMAN" 3 1042.579 1.2 1702 11888 2 1042.577556 522.2968 60S ribosomal protein L4 OS=Homo sapiens OX=9606 GN=RPL4 PE=1 SV=5 6.42 2756.9 - 281025 - - - -1.3965 - 1.876 0.39 - 345.6 1 1 0 -0.0015 9 0 0 0 1.82E+07 1.51E+07 - - - 3.7412 0.9906 221125_WJC_METTL3_EV_vs_WT_F01.11892.11892.2 1.12 12-Jul R.LLSVNIR.V sp|P07814|SYEP_HUMAN 1 813.5072 0.74 1704 11892 2 813.504276 407.7609 Bifunctional glutamate\proline--tRNA ligase OS=Homo sapiens OX=9606 GN=EPRS1 PE=1 SV=5 9.75 2757.4 - 1.50E+06 - - - -3.641 - 1.468 0.253 - 125.3 1 2 0 -0.003 7 0 0 0 1.22E+08 1.65E+08 - - - 2.1251 0.9887 221125_WJC_METTL3_EV_vs_WT_F01.11900.11900.2 0.258 12-Jul K.TC[160.03]PLLLR[166.11].V "sp|O00422|SAP18_HUMAN,tr|U3KQ12|U3KQ12_HUMAN,tr|U3KPY7|U3KPY7_HUMAN,tr|H7BZW6|H7BZW6_HUMAN" 4 881.5032 1.05 1707 11900 2 881.500999 441.7589 Histone deacetylase complex subunit SAP18 OS=Homo sapiens OX=9606 GN=SAP18 PE=1 SV=1 7.91 2758.4 - 1.66E+06 - - - -2.5298 - 1.335 0.188 - 222.3 1 2 0 -0.0022 7 0 0 0 4.88E+08 4.64E+08 - - - 1.3444 0.9989 221125_WJC_METTL3_EV_vs_WT_F01.11902.11902.2 0.000208 12-Sep R.YPDPLIK[136.11].V "sp|P62701|RS4X_HUMAN,sp|Q8TD47|RS4Y2_HUMAN" 2 852.4837 1.1 1708 11902 2 852.481647 427.2491 "40S ribosomal protein S4, X isoform OS=Homo sapiens OX=9606 GN=RPS4X PE=1 SV=2" 5.83 2758.6 - 3.60E+06 - - - -2.3555 - 1.682 0.354 - 227.1 1 2 0 -0.002 7 0 0 0 1.42E+09 1.29E+09 - - - 3.3026 0.9533 221125_WJC_METTL3_EV_vs_WT_F01.11904.11904.2 0.0244 16-Sep R.PLISVYSEK.G "sp|P36578|RL4_HUMAN,tr|H3BTP7|H3BTP7_HUMAN,tr|H3BU31|H3BU31_HUMAN" 3 1034.5648 1.18 1710 11904 2 1034.56363 518.2897 60S ribosomal protein L4 OS=Homo sapiens OX=9606 GN=RPL4 PE=1 SV=5 6.42 2758.9 - 498144 - - - -1.1425 - 1.652 0.31 - 296.1 1 1 0 -0.0012 9 0 0 0 1.82E+07 1.54E+07 - - - 2.7826 0.9964 221125_WJC_METTL3_EV_vs_WT_F01.11907.11907.2 0.0232 12-Jul K.TC[160.03]PLLLR.V "sp|O00422|SAP18_HUMAN,tr|U3KQ12|U3KQ12_HUMAN,tr|U3KPY7|U3KPY7_HUMAN,tr|H7BZW6|H7BZW6_HUMAN" 4 871.495 1.06 1711 11907 2 871.493068 436.7548 Histone deacetylase complex subunit SAP18 OS=Homo sapiens OX=9606 GN=SAP18 PE=1 SV=1 7.91 2759.3 - 1.55E+06 - - - -2.1698 - 1.314 0.289 - 234.6 1 2 0 -0.0019 7 0 0 0 4.90E+08 4.64E+08 - - - 2.0402 0.9991 221125_WJC_METTL3_EV_vs_WT_F01.11929.11929.2 0.256 12-Aug R.WLGEPIK.A "sp|O14744|ANM5_HUMAN,tr|H0YJX6|H0YJX6_HUMAN" 2 841.4698 2.71 1717 11929 2 841.469016 421.7422 Protein arginine N-methyltransferase 5 OS=Homo sapiens OX=9606 GN=PRMT5 PE=1 SV=4 6 2762.4 - 2.28E+06 - - - -0.9198 - 1.451 0.316 - 349.7 1 2 0 -0.0008 7 0 0 0 1.88E+09 6.94E+08 - - - 2.5542 0.996 221125_WJC_METTL3_EV_vs_WT_F01.11932.11932.2 0.111 12-Jul R.WLGEPIK[136.11].A "sp|O14744|ANM5_HUMAN,tr|H0YJX6|H0YJX6_HUMAN" 2 849.484 2.7 1718 11932 2 849.482793 425.7493 Protein arginine N-methyltransferase 5 OS=Homo sapiens OX=9606 GN=PRMT5 PE=1 SV=4 6 2762.8 - 1.38E+06 - - - -1.4091 - 1.169 0.273 - 250.2 1 2 0 -0.0012 7 0 0 0 1.88E+09 6.96E+08 - - - 1.5518 0.78 221125_WJC_METTL3_EV_vs_WT_F01.11933.11933.2 1.87 12-Aug K.FASFIDK.V "sp|Q86Y46|K2C73_HUMAN,sp|Q7RTS7|K2C74_HUMAN,sp|Q9NSB2|KRT84_HUMAN,sp|P48668|K2C6C_HUMAN,sp|Q3SY84|K2C71_HUMAN,sp|P05787|K2C8_HUMAN,sp|Q01546|K22O_HUMAN,sp|P19013|K2C4_HUMAN,sp|Q7Z794|K2C1B_HUMAN,sp|Q8N1N4|K2C78_HUMAN,sp|P12035|K2C3_HUMAN,sp|P04264|K2C1_HUMAN,sp|P04259|K2C6B_HUMAN,sp|P13647|K2C5_HUMAN,sp|P35908|K22E_HUMAN,sp|Q14CN4|K2C72_HUMAN,sp|P08729|K2C7_HUMAN,sp|O95678|K2C75_HUMAN,sp|Q5XKE5|K2C79_HUMAN,sp|P02538|K2C6A_HUMAN,tr|F8VUG2|F8VUG2_HUMAN,tr|F8W0C6|F8W0C6_HUMAN,tr|F8W1U3|F8W1U3_HUMAN,tr|H0YHD9|H0YHD9_HUMAN,tr|F8W1S1|F8W1S1_HUMAN,tr|F8VS61|F8VS61_HUMAN" 26 826.4225 38.86 1719 11933 2 827.424219 414.2185 "Keratin, type II cytoskeletal 73 OS=Homo sapiens OX=9606 GN=KRT73 PE=1 SV=1" 5.84 2762.9 - 2.95E+06 - - - 1212.1088 - 1.728 0.131 - 172.7 1 2 0 1.0017 7 0 0 0 7.68E+08 1.98E+07 - - - 1.4271 0.9968 221125_WJC_METTL3_EV_vs_WT_F01.11937.11937.2 0.478 12-Aug K.FASFIDK.V "sp|Q86Y46|K2C73_HUMAN,sp|Q7RTS7|K2C74_HUMAN,sp|Q9NSB2|KRT84_HUMAN,sp|P48668|K2C6C_HUMAN,sp|Q3SY84|K2C71_HUMAN,sp|P05787|K2C8_HUMAN,sp|Q01546|K22O_HUMAN,sp|P19013|K2C4_HUMAN,sp|Q7Z794|K2C1B_HUMAN,sp|Q8N1N4|K2C78_HUMAN,sp|P12035|K2C3_HUMAN,sp|P04264|K2C1_HUMAN,sp|P04259|K2C6B_HUMAN,sp|P13647|K2C5_HUMAN,sp|P35908|K22E_HUMAN,sp|Q14CN4|K2C72_HUMAN,sp|P08729|K2C7_HUMAN,sp|O95678|K2C75_HUMAN,sp|Q5XKE5|K2C79_HUMAN,sp|P02538|K2C6A_HUMAN,tr|F8VUG2|F8VUG2_HUMAN,tr|F8W0C6|F8W0C6_HUMAN,tr|F8W1U3|F8W1U3_HUMAN,tr|H0YHD9|H0YHD9_HUMAN,tr|F8W1S1|F8W1S1_HUMAN,tr|F8VS61|F8VS61_HUMAN" 26 826.4225 38.86 1721 11937 2 826.421323 414.2185 "Keratin, type II cytoskeletal 73 OS=Homo sapiens OX=9606 GN=KRT73 PE=1 SV=1" 5.84 2763.4 - 3.91E+06 - - - -1.4303 - 1.693 0.138 - 174.9 1 2 0 -0.0012 7 0 0 0 7.68E+08 1.98E+07 - - - 1.7281 0.9996 221125_WJC_METTL3_EV_vs_WT_F01.11944.11944.2 3.38E-06 24-Oct R.FSGSGSGTDFTLK.L "sp|A2NJV5|KV229_HUMAN,sp|A0A087WW87|KV240_HUMAN,sp|P06310|KV230_HUMAN,sp|A0A075B6S2|KVD29_HUMAN,sp|P01614|KVD40_HUMAN,sp|P01615|KVD28_HUMAN,sp|A0A075B6S6|KVD30_HUMAN,sp|A0A075B6P5|KV228_HUMAN,sp|A0A0A0MRZ7|KVD26_HUMAN" 9 1302.6092 999 1724 11944 2 1302.605586 652.3119 Immunoglobulin kappa variable 2-29 OS=Homo sapiens OX=9606 GN=IGKV2-29 PE=3 SV=2 5.84 2764.3 - 122709 - - - -2.7714 - 2.051 0.553 - 191 1 2 0 -0.0036 13 0 0 0 8.82E+06 0.00E+00 - - - 4.9679 0.9988 221125_WJC_METTL3_EV_vs_WT_F01.11973.11973.2 0.00716 12-Jul R.LVVFDAR.- sp|P53803|RPAB4_HUMAN 1 818.465 0.99 1731 11973 2 818.463893 410.2398 "DNA-directed RNA polymerases I, II, and III subunit RPABC4 OS=Homo sapiens OX=9606 GN=POLR2K PE=1 SV=1" 5.84 2768.7 - 720049 - - - -1.399 - 1.471 0.311 - 156 1 2 0 -0.0011 7 0 0 0 1.60E+08 1.62E+08 - - - 2.5606 0.9988 221125_WJC_METTL3_EV_vs_WT_F01.11977.11977.2 0.0531 18-Sep R.RVLQALEGLK.M "sp|P39019|RS19_HUMAN,tr|A0A075B6E2|A0A075B6E2_HUMAN" 2 1125.687 1.1 1733 11977 2 1125.68477 563.8508 40S ribosomal protein S19 OS=Homo sapiens OX=9606 GN=RPS19 PE=1 SV=2 8.75 2769.2 - 330687 - - - -1.9748 - 1.935 0.274 - 272 1 2 0 -0.0022 10 0 0 0 1.31E+07 1.19E+07 - - - 2.9066 0.9943 221125_WJC_METTL3_EV_vs_WT_F01.11990.11990.2 0.326 12-Jul R.VAFLVSR.L sp|Q6ICC9|RTL6_HUMAN 1 790.4701 1.3 1742 11990 2 790.468501 396.2423 Retrotransposon Gag-like protein 6 OS=Homo sapiens OX=9606 GN=RTL6 PE=2 SV=1 9.72 2770.8 - 736633 - - - -2.0532 - 1.515 0.168 - 169.4 1 2 0 -0.0016 7 0 0 0 3.61E+07 2.76E+07 - - - 1.5976 0.9483 221125_WJC_METTL3_EV_vs_WT_F01.12000.12000.2 0.102 14-Jul R.LPLQDVYK[136.11].L "sp|Q05639|EF1A2_HUMAN,sp|P68104|EF1A1_HUMAN,sp|Q5VTE0|EF1A3_HUMAN,tr|A0A7I2V659|A0A7I2V659_HUMAN,tr|A0A7I2V3H3|A0A7I2V3H3_HUMAN,tr|A0A2U3TZH3|A0A2U3TZH3_HUMAN,tr|A0A7I2V5N4|A0A7I2V5N4_HUMAN,tr|A0A087WVQ9|A0A087WVQ9_HUMAN,tr|A0A087WV01|A0A087WV01_HUMAN" 9 982.5579 0.64 1748 12000 2 982.55159 492.2862 Elongation factor 1-alpha 2 OS=Homo sapiens OX=9606 GN=EEF1A2 PE=1 SV=1 5.83 2772 - 357291 - - - -6.4047 - 1.513 0.275 - 157.2 1 2 0 -0.0063 8 0 0 0 3.96E+08 6.21E+08 - - - 2.3191 0.8379 221125_WJC_METTL3_EV_vs_WT_F01.12006.12006.2 10.9 12-Jun R.GLGQLIR[166.11].A "sp|Q5UIP0|RIF1_HUMAN,tr|H7C2B5|H7C2B5_HUMAN" 2 765.4736 0.001 1752 12006 2 765.472283 383.7441 Telomere-associated protein RIF1 OS=Homo sapiens OX=9606 GN=RIF1 PE=1 SV=2 9.75 2772.8 - 716040 - - - -1.7767 - 1.018 0.006 - 153.7 1 2 0 -0.0014 7 0 0 0 0.00E+00 2.35E+07 - - - -0.8586 0.9995 221125_WJC_METTL3_EV_vs_WT_F01.12019.12019.4 0.00073 10/108 R.GLLQDDAHPTLVTYADHSK[136.11].L "sp|Q86U44|MTA70_HUMAN,tr|F5H6D8|F5H6D8_HUMAN,tr|H0YFV6|H0YFV6_HUMAN,tr|B4DTN4|B4DTN4_HUMAN" 4 2088.0367 0.01 1760 12019 4 2088.029494 523.0165 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 5.13 2774.5 - 586470 - - - -3.4669 - 2.264 0.415 - 45.6 1 2 0 -0.0072 19 0 0 0 1.60E+05 3.00E+07 - - - 3.1126 0.9993 221125_WJC_METTL3_EV_vs_WT_F01.12025.12025.3 0.000407 Oct-72 R.GLLQDDAHPTLVTYADHSK[136.11].L "sp|Q86U44|MTA70_HUMAN,tr|F5H6D8|F5H6D8_HUMAN,tr|H0YFV6|H0YFV6_HUMAN,tr|B4DTN4|B4DTN4_HUMAN" 4 2088.0367 0.76 1764 12025 3 2088.02791 697.0195 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 5.13 2775.3 - 182953 - - - -4.2255 - 1.957 0.475 - 101.2 1 2 0 -0.0088 19 0 0 0 7.17E+06 9.48E+06 - - - 5.4829 0.9966 221125_WJC_METTL3_EV_vs_WT_F01.12049.12049.2 0.0289 12-Jun R.LVVFDAR[166.11].- sp|P53803|RPAB4_HUMAN 1 828.4733 1.01 1772 12049 2 828.471805 415.2439 "DNA-directed RNA polymerases I, II, and III subunit RPABC4 OS=Homo sapiens OX=9606 GN=POLR2K PE=1 SV=1" 5.84 2778.5 - 1.98E+06 - - - -1.8142 - 1.264 0.285 - 148.8 1 2 0 -0.0015 7 0 0 0 1.59E+08 1.58E+08 - - - 1.8879 0.9991 221125_WJC_METTL3_EV_vs_WT_F01.12055.12055.2 0.00354 14-Sep R.LPLQDVYK.L "sp|Q05639|EF1A2_HUMAN,sp|P68104|EF1A1_HUMAN,sp|Q5VTE0|EF1A3_HUMAN,tr|A0A7I2V659|A0A7I2V659_HUMAN,tr|A0A7I2V3H3|A0A7I2V3H3_HUMAN,tr|A0A2U3TZH3|A0A2U3TZH3_HUMAN,tr|A0A7I2V5N4|A0A7I2V5N4_HUMAN,tr|A0A087WVQ9|A0A087WVQ9_HUMAN,tr|A0A087WV01|A0A087WV01_HUMAN" 9 974.5437 0.56 1775 12055 2 974.542165 488.2791 Elongation factor 1-alpha 2 OS=Homo sapiens OX=9606 GN=EEF1A2 PE=1 SV=1 5.83 2779.2 - 1.23E+06 - - - -1.5577 - 1.722 0.303 - 310.7 1 2 0 -0.0015 8 0 0 0 3.50E+08 6.20E+08 - - - 2.9176 0.9995 221125_WJC_METTL3_EV_vs_WT_F01.12059.12059.2 0.279 14-Dec R.LGNSLLLK[136.11].Y sp|Q10570|CPSF1_HUMAN 1 864.5524 0.73 1776 12059 2 864.550865 433.2835 Cleavage and polyadenylation specificity factor subunit 1 OS=Homo sapiens OX=9606 GN=CPSF1 PE=1 SV=2 8.75 2779.8 - 1.59E+06 - - - -1.779 - 2.528 0.257 - 331.2 1 2 0 -0.0015 8 0 0 0 4.47E+07 6.10E+07 - - - 3.7358 0.9961 221125_WJC_METTL3_EV_vs_WT_F01.12069.12069.2 0.05 14-Sep K.LSAAIVLK.N sp|Q8WUM0|NU133_HUMAN 1 813.5324 1.63 1781 12069 2 813.530178 407.7735 Nuclear pore complex protein Nup133 OS=Homo sapiens OX=9606 GN=NUP133 PE=1 SV=2 8.75 2781.2 - 1.20E+06 - - - -2.719 - 1.972 0.166 - 166.9 1 2 0 -0.0022 8 0 0 0 1.79E+08 1.10E+08 - - - 2.3144 0.9982 221125_WJC_METTL3_EV_vs_WT_F01.12070.12070.2 0.845 12-Jul K.FLALEER.K "sp|Q8NEF3|CC112_HUMAN,tr|D6RF76|D6RF76_HUMAN" 2 876.4705 3.13 1782 12070 2 876.46896 439.2425 Coiled-coil domain-containing protein 112 OS=Homo sapiens OX=9606 GN=CCDC112 PE=1 SV=2 4.53 2781.4 - 765817 - - - -1.7776 - 1.52 0.273 - 186.8 1 2 0 -0.0016 7 0 0 0 3.28E+07 1.05E+07 - - - 2.3836 0.9983 221125_WJC_METTL3_EV_vs_WT_F01.12075.12075.2 0.133 12-Aug R.LAILYAK.R "sp|P50502|F10A1_HUMAN,sp|Q8NFI4|F10A5_HUMAN,sp|Q8IZP2|ST134_HUMAN,tr|Q3KNR6|Q3KNR6_HUMAN,tr|H7C3I1|H7C3I1_HUMAN,tr|F6VDH7|F6VDH7_HUMAN" 6 790.4953 1.23 1784 12075 2 790.494549 396.2549 Hsc70-interacting protein OS=Homo sapiens OX=9606 GN=ST13 PE=1 SV=2 8.59 2782.1 - 1.39E+06 - - - -0.9197 - 1.797 0.154 - 194.8 1 2 0 -0.0007 7 0 0 0 2.54E+08 2.06E+08 - - - 2.0354 0.9765 221125_WJC_METTL3_EV_vs_WT_F01.12079.12079.2 0.497 14-Jul R.LGNSLLLK.Y sp|Q10570|CPSF1_HUMAN 1 856.5382 0.73 1786 12079 2 856.535574 429.2764 Cleavage and polyadenylation specificity factor subunit 1 OS=Homo sapiens OX=9606 GN=CPSF1 PE=1 SV=2 8.75 2782.6 - 1.24E+06 - - - -3.0693 - 1.282 0.176 - 73.8 1 2 0 -0.0026 8 0 0 0 4.47E+07 6.10E+07 - - - 1.0893 0.9944 221125_WJC_METTL3_EV_vs_WT_F01.12086.12086.2 0.034 16-Sep K.IGPLGLSPK[136.11].K sp|P30050|RL12_HUMAN 1 888.5524 1.44 1788 12086 2 888.550654 445.2835 60S ribosomal protein L12 OS=Homo sapiens OX=9606 GN=RPL12 PE=1 SV=1 8.75 2783.6 - 1.61E+06 - - - -1.9684 - 1.858 0.099 - 179.9 1 2 0 -0.0017 9 0 0 0 1.01E+10 7.00E+09 - - - 1.5639 0.9884 221125_WJC_METTL3_EV_vs_WT_F01.12087.12087.2 1.63 12-Sep R.TLQVLIK[136.11].Q "sp|Q7Z3B4|NUP54_HUMAN,sp|P35219|CAH8_HUMAN" 2 821.5466 1.63 1789 12087 2 821.544209 411.7806 Nucleoporin p54 OS=Homo sapiens OX=9606 GN=NUP54 PE=1 SV=2 8.41 2783.6 - 1.47E+06 - - - -2.8982 - 1.485 0.167 - 193.5 1 2 0 -0.0024 7 0 0 0 1.79E+08 1.10E+08 - - - 1.5266 0.9753 221125_WJC_METTL3_EV_vs_WT_F01.12091.12091.2 1.16 12-Jul R.LLASLYR.D sp|P57740|NU107_HUMAN 1 834.4963 0.89 1791 12091 2 834.49425 418.2554 Nuclear pore complex protein Nup107 OS=Homo sapiens OX=9606 GN=NUP107 PE=1 SV=1 8.75 2784.2 - 1.58E+06 - - - -2.5033 - 1.24 0.141 - 139.9 1 2 0 -0.0021 7 0 0 0 1.55E+08 1.74E+08 - - - 0.7634 0.9904 221125_WJC_METTL3_EV_vs_WT_F01.12093.12093.2 0.0188 16-Jun K.IGPLGLSPK.K sp|P30050|RL12_HUMAN 1 880.5382 1.38 1792 12093 2 880.535901 441.2764 60S ribosomal protein L12 OS=Homo sapiens OX=9606 GN=RPL12 PE=1 SV=1 8.75 2784.4 - 2.90E+06 - - - -2.6143 - 1.189 0.267 - 85.2 1 2 0 -0.0023 9 0 0 0 1.01E+10 7.31E+09 - - - 1.5132 0.9774 221125_WJC_METTL3_EV_vs_WT_F01.12103.12103.2 0.143 14-Jul K.IPYTTVLR.L "sp|Q08945|SSRP1_HUMAN,tr|E9PMD4|E9PMD4_HUMAN" 2 961.5597 0.1 1797 12103 2 961.556842 481.7871 FACT complex subunit SSRP1 OS=Homo sapiens OX=9606 GN=SSRP1 PE=1 SV=1 8.75 2785.8 - 613625 - - - -2.9379 - 1.263 0.177 - 156.8 1 2 0 -0.0028 8 0 0 0 4.48E+07 4.29E+08 - - - 1.0516 0.9997 221125_WJC_METTL3_EV_vs_WT_F01.12107.12107.2 0.000162 16-Sep R.LYEALTPVH.- "sp|Q9UKF6|CPSF3_HUMAN,tr|G5E9W3|G5E9W3_HUMAN" 2 1041.5495 - 1799 12107 2 1041.548133 521.782 Cleavage and polyadenylation specificity factor subunit 3 OS=Homo sapiens OX=9606 GN=CPSF3 PE=1 SV=1 5.24 2786.2 - 800459 - - - -1.3086 - 1.78 0.428 - 239 1 2 0 -0.0014 9 0 0 0 - - - - - 3.87 0.9034 221125_WJC_METTL3_EV_vs_WT_F01.12126.12126.2 3.13 12-May R.GDIQTLK[136.11].N sp|Q9HC62|SENP2_HUMAN 1 781.4425 1.59 1808 12126 2 781.440733 391.7285 Sentrin-specific protease 2 OS=Homo sapiens OX=9606 GN=SENP2 PE=1 SV=3 5.84 2788.9 - 1.63E+06 - - - -2.2855 - 1.065 0.066 - 107 1 2 0 -0.0018 7 0 0 0 4.34E+08 2.73E+08 - - - -0.2725 0.8107 221125_WJC_METTL3_EV_vs_WT_F01.12127.12127.2 3.29 12-May K.LTATIWK[136.11].N sp|O15226|NKRF_HUMAN 1 839.4996 1.26 1809 12127 2 839.496997 420.7571 NF-kappa-B-repressing factor OS=Homo sapiens OX=9606 GN=NKRF PE=1 SV=2 8.75 2788.9 - 853650 - - - -3.1483 - 1.134 0.045 - 58 2 2 0 -0.0026 7 0 0 0 4.39E+07 3.50E+07 - - - -0.3635 0.9823 221125_WJC_METTL3_EV_vs_WT_F01.12131.12131.2 6.65 16-Jul K.LVPVGYGIR.K "sp|P29692|EF1D_HUMAN,tr|A0A087X1X7|A0A087X1X7_HUMAN,tr|E9PQZ1|E9PQZ1_HUMAN,tr|E9PQC9|E9PQC9_HUMAN,tr|E9PRY8|E9PRY8_HUMAN,tr|E9PK01|E9PK01_HUMAN,tr|H0YE58|H0YE58_HUMAN" 7 972.5757 1.79 1811 12131 2 972.574605 487.2951 Elongation factor 1-delta OS=Homo sapiens OX=9606 GN=EEF1D PE=1 SV=5 8.75 2789.5 - 6.65E+06 - - - -1.0765 - 1.198 0.11 - 164.9 1 2 0 -0.001 9 0 0 0 9.31E+08 5.21E+08 - - - 0.3758 0.9958 221125_WJC_METTL3_EV_vs_WT_F01.12132.12132.2 0.267 12-Jul K.FLEPTLR.L "sp|P14868|SYDC_HUMAN,tr|H7BZ35|H7BZ35_HUMAN" 2 874.4913 0.86 1812 12132 2 874.490437 438.2529 "Aspartate--tRNA ligase, cytoplasmic OS=Homo sapiens OX=9606 GN=DARS1 PE=1 SV=2" 6 2789.5 - 4.87E+06 - - - -0.9331 - 1.465 0.166 - 205.8 2 2 0 -0.0008 7 0 0 0 1.73E+08 2.01E+08 - - - 1.3423 0.9988 221125_WJC_METTL3_EV_vs_WT_F01.12137.12137.2 0.00156 20-Sep R.TAAENDFVTLK.K sp|P35908|K22E_HUMAN 1 1207.6085 134.04 1815 12137 2 1207.606264 604.8115 "Keratin, type II cytoskeletal 2 epidermal OS=Homo sapiens OX=9606 GN=KRT2 PE=1 SV=2" 4.37 2790.2 - 161652 - - - -1.8251 - 1.914 0.275 - 231.2 1 2 0 -0.0022 11 0 0 0 8.73E+06 6.51E+04 - - - 2.8277 0.9956 221125_WJC_METTL3_EV_vs_WT_F01.12138.12138.2 0.791 12-Aug R.LAILYAK[136.11].R "sp|P50502|F10A1_HUMAN,sp|Q8NFI4|F10A5_HUMAN,sp|Q8IZP2|ST134_HUMAN,tr|Q3KNR6|Q3KNR6_HUMAN,tr|H7C3I1|H7C3I1_HUMAN,tr|F6VDH7|F6VDH7_HUMAN" 6 798.5095 1.21 1816 12138 2 798.508364 400.262 Hsc70-interacting protein OS=Homo sapiens OX=9606 GN=ST13 PE=1 SV=2 8.59 2790.2 - 3.98E+06 - - - -1.3926 - 1.764 0.086 - 212.2 1 2 0 -0.0011 7 0 0 0 2.55E+08 2.10E+08 - - - 1.4743 0.9862 221125_WJC_METTL3_EV_vs_WT_F01.12157.12157.2 0.741 12-Jul R.LLTGLYR[166.11].D "sp|Q9Y5M8|SRPRB_HUMAN,tr|C9J5Z8|C9J5Z8_HUMAN" 2 844.5046 0.82 1827 12157 2 844.503663 423.2596 Signal recognition particle receptor subunit beta OS=Homo sapiens OX=9606 GN=SRPRB PE=1 SV=3 8.75 2792.6 - 2.89E+06 - - - -1.1202 - 1.52 0.026 - 147.3 1 2 0 -0.0009 7 0 0 0 1.61E+08 1.96E+08 - - - 0.5594 0.9233 221125_WJC_METTL3_EV_vs_WT_F01.12162.12162.2 4.36 12-May R.LVNQWIK[136.11].Q "sp|P43246|MSH2_HUMAN,tr|A0A2R8YG02|A0A2R8YG02_HUMAN,tr|A0A2R8Y7S8|A0A2R8Y7S8_HUMAN,tr|E9PHA6|E9PHA6_HUMAN,tr|A0A2R8YFH0|A0A2R8YFH0_HUMAN,tr|A0A2R8Y6P0|A0A2R8Y6P0_HUMAN" 6 907.5371 0.63 1830 12162 2 907.535862 454.7758 DNA mismatch repair protein Msh2 OS=Homo sapiens OX=9606 GN=MSH2 PE=1 SV=1 8.75 2793.2 - 693125 - - - -1.3509 - 0.991 0.066 - 65.2 1 2 0 -0.0012 7 0 0 0 1.51E+07 2.41E+07 - - - -0.5006 0.9936 221125_WJC_METTL3_EV_vs_WT_F01.12164.12164.2 0.261 16-Jul K.LVPVGYGIR[166.11].K "sp|P29692|EF1D_HUMAN,tr|A0A087X1X7|A0A087X1X7_HUMAN,tr|E9PQZ1|E9PQZ1_HUMAN,tr|E9PQC9|E9PQC9_HUMAN,tr|E9PRY8|E9PRY8_HUMAN,tr|E9PK01|E9PK01_HUMAN,tr|H0YE58|H0YE58_HUMAN" 7 982.5839 1.78 1831 12164 2 982.583018 492.2992 Elongation factor 1-delta OS=Homo sapiens OX=9606 GN=EEF1D PE=1 SV=5 8.75 2793.5 - 7.10E+06 - - - -0.92 - 1.261 0.178 - 158.6 1 2 0 -0.0009 9 0 0 0 9.24E+08 5.18E+08 - - - 1.0263 0.9975 221125_WJC_METTL3_EV_vs_WT_F01.12182.12182.2 0.0367 12-Jul R.TILMMGR[166.11].Y sp|P13639|EF2_HUMAN 1 830.4382 0.38 1839 12182 2 830.436705 416.2264 Elongation factor 2 OS=Homo sapiens OX=9606 GN=EEF2 PE=1 SV=4 9.41 2795.8 - 2.35E+06 - - - -1.7822 - 1.182 0.343 - 179.5 1 2 0 -0.0015 7 0 0 0 1.50E+08 4.01E+08 - - - 2.1037 0.9976 221125_WJC_METTL3_EV_vs_WT_F01.12205.12205.2 0.00963 18-Sep K.DVNAAIATIK[136.11].T "sp|Q6PEY2|TBA3E_HUMAN,sp|P0DPH7|TBA3C_HUMAN,sp|Q71U36|TBA1A_HUMAN,sp|P0DPH8|TBA3D_HUMAN,sp|P68363|TBA1B_HUMAN,sp|Q9BQE3|TBA1C_HUMAN,tr|A0A1W2PQM2|A0A1W2PQM2_HUMAN,tr|F5H5D3|F5H5D3_HUMAN" 8 1022.5852 0.82 1846 12205 2 1022.581917 512.2999 Tubulin alpha-3E chain OS=Homo sapiens OX=9606 GN=TUBA3E PE=1 SV=2 5.84 2799.1 - 243457 - - - -3.1714 - 1.63 0.363 - 197.3 1 2 0 -0.0032 10 0 0 0 4.91E+06 6.00E+06 - - - 3.0849 0.9979 221125_WJC_METTL3_EV_vs_WT_F01.12209.12209.2 0.177 14-Sep K.FGELVMTK[136.11].E "sp|P40939|ECHA_HUMAN,tr|A0A2R8YG21|A0A2R8YG21_HUMAN,tr|H0YFD6|H0YFD6_HUMAN,tr|A0A2R8Y4F5|A0A2R8Y4F5_HUMAN" 4 931.4928 4.42 1847 12209 2 931.490866 466.7537 "Trifunctional enzyme subunit alpha, mitochondrial OS=Homo sapiens OX=9606 GN=HADHA PE=1 SV=2" 6 2799.6 - 1.35E+06 - - - -2.1192 - 1.573 0.279 - 202.9 1 2 0 -0.002 8 0 0 0 5.34E+08 1.21E+08 - - - 2.4673 0.9889 221125_WJC_METTL3_EV_vs_WT_F01.12212.12212.2 10.7 12-Jul R.VC[160.03]DLLLK.K "sp|O75179|ANR17_HUMAN,tr|A0A1W2PQ15|A0A1W2PQ15_HUMAN,tr|H0YLQ3|H0YLQ3_HUMAN" 3 859.4837 3.37 1848 12212 2 859.482134 430.7491 Ankyrin repeat domain-containing protein 17 OS=Homo sapiens OX=9606 GN=ANKRD17 PE=1 SV=3 5.8 2800 - 1.11E+06 - - - -1.8511 - 1.163 0.201 - 111.7 1 2 0 -0.0016 7 0 0 0 4.63E+07 1.37E+07 - - - 1.0035 0.9459 221125_WJC_METTL3_EV_vs_WT_F01.12218.12218.2 2.95 12-May R.GDIQTLK.N sp|Q9HC62|SENP2_HUMAN 1 773.4283 1.34 1850 12218 2 773.42705 387.7214 Sentrin-specific protease 2 OS=Homo sapiens OX=9606 GN=SENP2 PE=1 SV=3 5.84 2800.8 - 2.18E+06 - - - -1.6407 - 1.197 0.031 - 137.2 1 2 0 -0.0013 7 0 0 0 4.89E+08 3.64E+08 - - - -0.1607 0.9722 221125_WJC_METTL3_EV_vs_WT_F01.12219.12219.2 3.99 18-Jun R.LIAAATSVLK[136.11].T "sp|P24863|CCNC_HUMAN,tr|E5RFX8|E5RFX8_HUMAN,tr|E5RI39|E5RI39_HUMAN,tr|J3KP90|J3KP90_HUMAN,tr|E5RFK5|E5RFK5_HUMAN,tr|G5E954|G5E954_HUMAN,tr|H0YBQ5|H0YBQ5_HUMAN" 7 993.6314 0.67 1851 12219 2 993.632631 497.823 Cyclin-C OS=Homo sapiens OX=9606 GN=CCNC PE=1 SV=2 8.75 2801 - 444704 - - - 1.257 - 1.23 0.137 - 49.4 9 2 0 0.0012 10 0 0 0 4.55E+06 6.80E+06 - - - 0.2041 0.9852 221125_WJC_METTL3_EV_vs_WT_F01.12222.12222.2 2.15 12-May R.TILMMGR.Y sp|P13639|EF2_HUMAN 1 820.4299 0.38 1852 12222 2 820.428664 411.2222 Elongation factor 2 OS=Homo sapiens OX=9606 GN=EEF2 PE=1 SV=4 9.41 2801.4 - 3.34E+06 - - - -1.5248 - 1.158 0.156 - 86.3 1 2 0 -0.0013 7 0 0 0 1.50E+08 4.01E+08 - - - 0.6576 0.999 221125_WJC_METTL3_EV_vs_WT_F01.12225.12225.2 0.0164 18-Jun R.QVLDNLTMEK.S "sp|P35527|K1C9_HUMAN,tr|K7EQQ3|K7EQQ3_HUMAN" 2 1189.6013 999 1854 12225 2 1189.601017 595.8079 "Keratin, type I cytoskeletal 9 OS=Homo sapiens OX=9606 GN=KRT9 PE=1 SV=3" 4.37 2801.7 - 283034 - - - -0.216 - 1.31 0.351 - 106.1 1 2 0 -0.0003 10 0 0 0 1.84E+07 0.00E+00 - - - 2.3871 0.9655 221125_WJC_METTL3_EV_vs_WT_F01.12232.12232.2 2.08 12-Jul K.LLEGIVK[136.11].D "sp|O15504|NUP42_HUMAN,tr|B4DT96|B4DT96_HUMAN,tr|C9JYA1|C9JYA1_HUMAN" 3 778.5044 1.18 1856 12232 2 778.502121 390.2595 Nucleoporin NUP42 OS=Homo sapiens OX=9606 GN=NUP42 PE=1 SV=1 6 2802.7 - 417835 - - - -2.9158 - 1.428 0.095 - 109.9 2 2 0 -0.0023 7 0 0 0 6.36E+07 5.40E+07 - - - 0.7364 0.9873 221125_WJC_METTL3_EV_vs_WT_F01.12234.12234.2 0.812 12-Aug K.LLEGIVK.D "sp|O15504|NUP42_HUMAN,tr|B4DT96|B4DT96_HUMAN,tr|C9JYA1|C9JYA1_HUMAN" 3 770.4902 1.2 1858 12234 2 770.488336 386.2524 Nucleoporin NUP42 OS=Homo sapiens OX=9606 GN=NUP42 PE=1 SV=1 6 2802.9 - 1.12E+06 - - - -2.4076 - 1.517 0.112 - 160.4 1 2 0 -0.0019 7 0 0 0 6.36E+07 5.32E+07 - - - 1.1881 0.9959 221125_WJC_METTL3_EV_vs_WT_F01.12238.12238.2 0.0246 14-Jul K.SALALAIK.V "sp|P25789|PSA4_HUMAN,tr|H0YKS0|H0YKS0_HUMAN,tr|H0YKT8|H0YKT8_HUMAN,tr|H0YMI6|H0YMI6_HUMAN,tr|H0YMA1|H0YMA1_HUMAN,tr|H0YL69|H0YL69_HUMAN,tr|H0YN18|H0YN18_HUMAN,tr|H0YMZ1|H0YMZ1_HUMAN" 8 785.5011 1.09 1860 12238 2 785.499556 393.7578 Proteasome subunit alpha type-4 OS=Homo sapiens OX=9606 GN=PSMA4 PE=1 SV=1 8.47 2803.4 - 3.51E+06 - - - -1.9529 - 1.469 0.217 - 172.1 1 2 0 -0.0015 8 0 0 0 2.19E+08 2.00E+08 - - - 1.8032 0.8522 221125_WJC_METTL3_EV_vs_WT_F01.12240.12240.3 0.203 Jul-36 R.LVNHFVEEFK[136.11].R "sp|P0DMV8|HS71A_HUMAN,sp|P0DMV9|HS71B_HUMAN,tr|V9GZ37|V9GZ37_HUMAN,tr|A0A0G2JIW1|A0A0G2JIW1_HUMAN" 4 1268.6645 0.16 1861 12240 3 1268.662695 423.8954 Heat shock 70 kDa protein 1A OS=Homo sapiens OX=9606 GN=HSPA1A PE=1 SV=1 5.4 2803.6 - 526311 - - - -1.4015 - 1.317 0.107 - 60.7 3 2 0 -0.0018 10 0 0 0 1.28E+07 7.86E+07 - - - 0.3158 0.9994 221125_WJC_METTL3_EV_vs_WT_F01.12253.12253.2 0.00642 18-Jul R.VLTAVEMGMK.N sp|Q9BVS4|RIOK2_HUMAN 1 1077.5562 0.76 1867 12253 2 1077.554404 539.7854 Serine\threonine-protein kinase RIO2 OS=Homo sapiens OX=9606 GN=RIOK2 PE=1 SV=2 5.97 2805.5 - 145957 - - - -1.702 - 1.682 0.388 - 120.4 1 2 0 -0.0018 10 0 0 0 6.98E+06 9.17E+06 - - - 3.3576 0.9988 221125_WJC_METTL3_EV_vs_WT_F01.12265.12265.2 0.029 14-Jul K.LGIYEAMK.L sp|P15924|DESP_HUMAN 1 923.4786 4.43 1872 12265 2 923.47776 462.7466 Desmoplakin OS=Homo sapiens OX=9606 GN=DSP PE=1 SV=3 6 2806.9 - 1.26E+07 - - - -0.9529 - 1.557 0.267 - 123.3 1 2 0 -0.0009 8 0 0 0 5.33E+08 1.20E+08 - - - 2.3481 0.9994 221125_WJC_METTL3_EV_vs_WT_F01.12273.12273.2 1.29E-05 14/18 R.LVNHFVEEFK[136.11].R "sp|P0DMV8|HS71A_HUMAN,sp|P0DMV9|HS71B_HUMAN,tr|V9GZ37|V9GZ37_HUMAN,tr|A0A0G2JIW1|A0A0G2JIW1_HUMAN" 4 1268.6645 0.18 1875 12273 2 1268.660845 635.3395 Heat shock 70 kDa protein 1A OS=Homo sapiens OX=9606 GN=HSPA1A PE=1 SV=1 5.4 2808 - 443944 - - - -2.8597 - 2.267 0.45 - 451.8 1 2 0 -0.0036 10 0 0 0 3.47E+06 1.97E+07 - - - 4.6481 0.9101 221125_WJC_METTL3_EV_vs_WT_F01.12304.12304.2 0.503 14-Aug D.IADIEALK[136.11].E "sp|Q70CQ2|UBP34_HUMAN,sp|O75792|RNH2A_HUMAN,tr|A0A2R8Y606|A0A2R8Y606_HUMAN,tr|A0A2R8Y658|A0A2R8Y658_HUMAN" 4 879.5157 1.57 1889 12304 2 879.515299 440.7651 Ubiquitin carboxyl-terminal hydrolase 34 OS=Homo sapiens OX=9606 GN=USP34 PE=1 SV=2 4.37 2812.2 - 4.88E+06 - - - -0.4377 - 1.688 0.182 - 131.1 1 1 0 -0.0004 8 0 0 0 3.03E+08 1.92E+08 - - - 1.9641 0.9491 221125_WJC_METTL3_EV_vs_WT_F01.12309.12309.2 6.43 Apr-32 K.IISNASC[160.03]TTNC[160.03]LAPLAK[136.11].V "sp|P04406|G3P_HUMAN,tr|E7EUT5|E7EUT5_HUMAN" 2 1840.9267 1.38 1891 12309 2 1840.928174 921.4706 Glyceraldehyde-3-phosphate dehydrogenase OS=Homo sapiens OX=9606 GN=GAPDH PE=1 SV=3 8.06 2812.9 - 62959 - - - 0.8251 - 0.657 0.226 - 30.8 1 2 0 0.0015 17 0 0 0 1.52E+06 1.10E+06 - - - -0.323 0.9995 221125_WJC_METTL3_EV_vs_WT_F01.12316.12316.2 0.00483 16-Nov K.IGPLGLSPK[136.11].K sp|P30050|RL12_HUMAN 1 888.5524 1.44 1894 12316 2 888.551577 445.2835 60S ribosomal protein L12 OS=Homo sapiens OX=9606 GN=RPL12 PE=1 SV=1 8.75 2813.8 - 902856 - - - -0.9296 - 1.704 0.344 - 302.7 1 2 0 -0.0008 9 0 0 0 1.01E+10 7.00E+09 - - - 3.1235 0.9983 221125_WJC_METTL3_EV_vs_WT_F01.12318.12318.2 0.00237 May-32 K.IISNASC[160.03]TTNC[160.03]LAPLAK.V "sp|P04406|G3P_HUMAN,tr|E7EUT5|E7EUT5_HUMAN" 2 1832.9125 1.38 1896 12318 2 1832.912213 917.4635 Glyceraldehyde-3-phosphate dehydrogenase OS=Homo sapiens OX=9606 GN=GAPDH PE=1 SV=3 8.06 2814 - 72018.3 - - - -0.132 - 1.002 0.387 - 49.3 1 2 0 -0.0002 17 0 0 0 1.52E+06 1.10E+06 - - - 1.9042 0.987 221125_WJC_METTL3_EV_vs_WT_F01.12325.12325.2 0.325 14-Jul K.LGIYEAMK.L sp|P15924|DESP_HUMAN 1 923.4786 4.43 1900 12325 2 923.479214 462.7466 Desmoplakin OS=Homo sapiens OX=9606 GN=DSP PE=1 SV=3 6 2814.9 - 529615 - - - 0.6216 - 1.275 0.102 - 96.9 1 2 0 0.0006 8 0 0 0 5.33E+08 1.20E+08 - - - 0.5269 0.86 221125_WJC_METTL3_EV_vs_WT_F01.12328.12328.2 13.9 14-Jun K.IGDFGLAR.D "sp|P08922|ROS1_HUMAN,sp|P07333|CSF1R_HUMAN,sp|P51617|IRAK1_HUMAN,sp|Q96PY6|NEK1_HUMAN,sp|P51955|NEK2_HUMAN,sp|Q6P3R8|NEK5_HUMAN,sp|Q16659|MK06_HUMAN,sp|P31152|MK04_HUMAN,tr|E9PIX7|E9PIX7_HUMAN,tr|H7C2I6|H7C2I6_HUMAN,tr|K7EN18|K7EN18_HUMAN,tr|A0A494C168|A0A494C168_HUMAN,tr|F6U4U2|F6U4U2_HUMAN,tr|H7C224|H7C224_HUMAN,tr|K7ELV1|K7ELV1_HUMAN,tr|Q5H8Y1|Q5H8Y1_HUMAN,tr|A0A3B3ITQ6|A0A3B3ITQ6_HUMAN,tr|D3YTB5|D3YTB5_HUMAN" 18 847.4552 19.02 1902 12328 2 847.455737 424.7349 Proto-oncogene tyrosine-protein kinase ROS OS=Homo sapiens OX=9606 GN=ROS1 PE=1 SV=3 5.84 2815.3 - 487503 - - - 0.6313 - 1.019 0.022 - 51.8 5 2 0 0.0005 8 0 0 0 3.38E+07 1.78E+06 - - - -1.0521 0.9693 221125_WJC_METTL3_EV_vs_WT_F01.12330.12330.2 0.187 12-May R.FPPYYMR[166.11].R "sp|P67809|YBOX1_HUMAN,tr|H0Y449|H0Y449_HUMAN,tr|C9J5V9|C9J5V9_HUMAN" 3 982.461 0.97 1904 12330 2 982.459399 492.2378 Y-box-binding protein 1 OS=Homo sapiens OX=9606 GN=YBX1 PE=1 SV=3 8.59 2815.5 - 212478 - - - -1.6591 - 0.926 0.193 - 83.5 1 2 0 -0.0016 7 0 0 0 4.80E+06 4.95E+06 - - - 0.2224 0.9693 221125_WJC_METTL3_EV_vs_WT_F01.12331.12331.2 0.471 16-May R.YVMVGLASR.R "sp|Q9C0C7|AMRA1_HUMAN,tr|A0A075B6T1|A0A075B6T1_HUMAN" 2 994.527 0.24 1905 12331 2 994.527718 498.2708 Activating molecule in BECN1-regulated autophagy protein 1 OS=Homo sapiens OX=9606 GN=AMBRA1 PE=1 SV=2 8.75 2815.6 - 130941 - - - 0.735 - 0.982 0.153 - 54.9 2 2 0 0.0007 9 0 0 0 4.86E+06 2.00E+07 - - - -0.0162 0.9978 221125_WJC_METTL3_EV_vs_WT_F01.12336.12336.2 0.888 14-Aug R.LPVDIAYK.R sp|P15924|DESP_HUMAN 1 917.5222 16.35 1908 12336 2 917.522415 459.7684 Desmoplakin OS=Homo sapiens OX=9606 GN=DSP PE=1 SV=3 5.83 2816.4 - 1.18E+06 - - - 0.2136 - 1.456 0.211 - 220.9 1 2 0 0.0002 8 0 0 0 4.50E+08 2.75E+07 - - - 1.7325 0.9981 221125_WJC_METTL3_EV_vs_WT_F01.12342.12342.2 0.14 16-Jun R.LVPLVNGVR[166.11].E "sp|Q6UB35|C1TM_HUMAN,tr|A0A087WVM4|A0A087WVM4_HUMAN,tr|B7ZM99|B7ZM99_HUMAN" 3 975.6105 0.79 1911 12342 2 975.611295 488.8125 "Monofunctional C1-tetrahydrofolate synthase, mitochondrial OS=Homo sapiens OX=9606 GN=MTHFD1L PE=1 SV=1" 9.75 2817.2 - 189253 - - - 0.8446 - 1.429 0.263 - 86.6 1 2 0 0.0008 9 0 0 0 7.54E+07 9.53E+07 - - - 2.016 0.9674 221125_WJC_METTL3_EV_vs_WT_F01.12364.12364.2 0.632 16-May K.EMEQLVLDK.K sp|Q96A49|SYAP1_HUMAN 1 1103.5533 1.23 1922 12364 2 1103.554236 552.7839 Synapse-associated protein 1 OS=Homo sapiens OX=9606 GN=SYAP1 PE=1 SV=1 4.14 2820.1 - 134731 - - - 0.8835 - 1.044 0.129 - 91.1 2 2 0 0.001 9 0 0 0 3.00E+06 2.45E+06 - - - -0.0164 0.9977 221125_WJC_METTL3_EV_vs_WT_F01.12371.12371.2 0.0213 14-Aug K.GYGFGMVK[136.11].L "sp|Q9Y277|VDAC3_HUMAN,tr|E5RHE1|E5RHE1_HUMAN,tr|E5RJN6|E5RJN6_HUMAN,tr|E5RFL1|E5RFL1_HUMAN,tr|E5RFP6|E5RFP6_HUMAN,tr|E5RHZ6|E5RHZ6_HUMAN" 6 865.4248 1.02 1927 12371 2 865.424699 433.7197 Voltage-dependent anion-selective channel protein 3 OS=Homo sapiens OX=9606 GN=VDAC3 PE=1 SV=1 8.59 2820.9 - 748671 - - - -0.0705 - 1.27 0.258 - 169.4 1 2 0 -0.0001 8 0 0 0 1.87E+07 1.83E+07 - - - 1.6674 0.9994 221125_WJC_METTL3_EV_vs_WT_F01.12373.12373.2 0.792 18-Oct R.ISGLIYEETR.G sp|P62805|H4_HUMAN 1 1179.6136 1.7 1929 12373 2 1179.61508 590.8141 Histone H4 OS=Homo sapiens OX=9606 GN=H4C1 PE=1 SV=2 4.53 2821.2 - 150935 - - - 1.2945 - 2.023 0.301 - 304.2 1 2 0 0.0015 10 0 0 0 9.03E+06 5.33E+06 - - - 3.2304 0.998 221125_WJC_METTL3_EV_vs_WT_F01.12379.12379.2 0.189 12-Aug R.VAIFIEK[136.11].T sp|Q9P258|RCC2_HUMAN 1 826.5044 0.64 1933 12379 2 826.503181 414.2595 Protein RCC2 OS=Homo sapiens OX=9606 GN=RCC2 PE=1 SV=2 5.97 2821.8 - 923041 - - - -1.464 - 1.958 0.131 - 202.4 1 2 0 -0.0012 7 0 0 0 3.61E+07 5.61E+07 - - - 2.1372 0.8215 221125_WJC_METTL3_EV_vs_WT_F01.12381.12381.2 1.1 12-Jul A.LLLIESR.C "sp|Q15386|UBE3C_HUMAN,sp|P62277|RS13_HUMAN,sp|Q14406|CSHL_HUMAN,tr|J3QT06|J3QT06_HUMAN,tr|H0YKQ4|H0YKQ4_HUMAN,tr|A0A0B4J1R0|A0A0B4J1R0_HUMAN,tr|H7C3R7|H7C3R7_HUMAN" 7 842.5226 1 1935 12381 2 842.521513 422.2686 Ubiquitin-protein ligase E3C OS=Homo sapiens OX=9606 GN=UBE3C PE=1 SV=3 6 2822 - 1.11E+06 - - - -1.2344 - 1.507 0.165 - 177.7 1 1 0 -0.001 7 0 0 0 2.70E+09 2.69E+09 - - - 1.5589 0.9939 221125_WJC_METTL3_EV_vs_WT_F01.12395.12395.2 0.201 14-Aug R.VIAQLEIR.Q "sp|Q9UPN3|MACF1_HUMAN,tr|H3BQK9|H3BQK9_HUMAN,tr|A0A7P0MQR8|A0A7P0MQR8_HUMAN,tr|E9PNZ4|E9PNZ4_HUMAN,tr|H0Y390|H0Y390_HUMAN,tr|E9PLY5|E9PLY5_HUMAN,tr|H3BPE1|H3BPE1_HUMAN,tr|A0A669KBB0|A0A669KBB0_HUMAN,tr|A0A590UJG2|A0A590UJG2_HUMAN,tr|A0A5F9ZGX0|A0A5F9ZGX0_HUMAN" 10 940.5706 1.64 1942 12395 2 940.569835 471.2926 "Microtubule-actin cross-linking factor 1, isoforms 1\2\3\5 OS=Homo sapiens OX=9606 GN=MACF1 PE=1 SV=4" 5.97 2823.7 - 507209 - - - -0.7772 - 1.24 0.181 - 205.1 1 2 0 -0.0007 8 0 0 0 8.60E+06 5.23E+06 - - - 1.0264 0.9889 221125_WJC_METTL3_EV_vs_WT_F01.12400.12400.2 0.167 14-Jul R.LPVDIAYK[136.11].R sp|P15924|DESP_HUMAN 1 925.5364 16.09 1945 12400 2 925.533664 463.7755 Desmoplakin OS=Homo sapiens OX=9606 GN=DSP PE=1 SV=3 5.83 2824.3 - 633765 - - - -2.9767 - 1.402 0.209 - 118.5 1 2 0 -0.0028 8 0 0 0 4.50E+08 2.80E+07 - - - 1.6029 0.9744 221125_WJC_METTL3_EV_vs_WT_F01.12402.12402.2 0.089 12-Jun R.LSSFIVK.E sp|P24278|ZBT25_HUMAN 1 792.4745 0.82 1946 12402 2 792.474462 397.2445 Zinc finger and BTB domain-containing protein 25 OS=Homo sapiens OX=9606 GN=ZBTB25 PE=1 SV=2 8.75 2824.5 - 516705 - - - -0.0997 - 1.439 0.009 - 75.4 4 2 0 -0.0001 7 0 0 0 2.49E+07 3.03E+07 - - - -0.0083 0.9935 221125_WJC_METTL3_EV_vs_WT_F01.12412.12412.2 0.577 14-Jul R.QMAAVLLR.R "sp|O00410|IPO5_HUMAN,tr|E7ETV3|E7ETV3_HUMAN,tr|E7ETV8|E7ETV8_HUMAN,tr|C9JQT6|C9JQT6_HUMAN,tr|C9JZD8|C9JZD8_HUMAN,tr|E7EWK4|E7EWK4_HUMAN,tr|E7EV12|E7EV12_HUMAN,tr|E7EX05|E7EX05_HUMAN,tr|H0Y8C6|H0Y8C6_HUMAN,tr|E7EQT5|E7EQT5_HUMAN,tr|E7ESZ1|E7ESZ1_HUMAN" 11 900.5215 0.92 1951 12412 2 900.51972 451.268 Importin-5 OS=Homo sapiens OX=9606 GN=IPO5 PE=1 SV=4 9.75 2825.8 - 388969 - - - -1.9855 - 1.504 0.162 - 216.1 1 2 0 -0.0018 8 0 0 0 4.81E+07 5.22E+07 - - - 1.4679 0.9991 221125_WJC_METTL3_EV_vs_WT_F01.12417.12417.2 0.000574 16-Jul K.AFADPEVLR.R "sp|O75179|ANR17_HUMAN,sp|Q8IWZ3|ANKH1_HUMAN,tr|E9PDP5|E9PDP5_HUMAN,tr|H0YM23|H0YM23_HUMAN,tr|A0A1W2PQ15|A0A1W2PQ15_HUMAN" 5 1016.5291 2.54 1954 12417 2 1016.527346 509.2718 Ankyrin repeat domain-containing protein 17 OS=Homo sapiens OX=9606 GN=ANKRD17 PE=1 SV=3 4.37 2826.5 - 458229 - - - -1.7206 - 1.447 0.39 - 175 1 2 0 -0.0018 9 0 0 0 1.46E+08 5.76E+07 - - - 2.99 0.9991 221125_WJC_METTL3_EV_vs_WT_F01.12425.12425.2 0.0144 20-Oct K.LIADVAPSAIR[166.11].E "sp|P39748|FEN1_HUMAN,tr|F5H1Y3|F5H1Y3_HUMAN" 2 1134.6636 0.55 1957 12425 2 1134.662728 568.3391 Flap endonuclease 1 OS=Homo sapiens OX=9606 GN=FEN1 PE=1 SV=1 5.84 2827.5 - 246478 - - - -0.7941 - 1.739 0.272 - 333.6 1 2 0 -0.0009 11 0 0 0 4.03E+07 7.31E+07 - - - 2.5465 0.9991 221125_WJC_METTL3_EV_vs_WT_F01.12427.12427.2 0.301 12-Jun R.MLLDQYR.K sp|Q16706|MA2A1_HUMAN 1 937.4691 1.14 1958 12427 2 937.468265 469.7418 Alpha-mannosidase 2 OS=Homo sapiens OX=9606 GN=MAN2A1 PE=1 SV=2 5.59 2827.7 - 500223 - - - -0.9312 - 1.39 0.335 - 168.2 1 2 0 -0.0009 7 0 0 0 1.61E+07 1.41E+07 - - - 2.5585 0.9835 221125_WJC_METTL3_EV_vs_WT_F01.12430.12430.2 1.16 12-Jun K.ELVTLYR.R sp|Q8TD55|PKHO2_HUMAN 1 892.5018 1 1961 12430 2 892.498994 447.2582 Pleckstrin homology domain-containing family O member 2 OS=Homo sapiens OX=9606 GN=PLEKHO2 PE=1 SV=1 6.1 2828 - 542456 - - - -3.1641 - 1.4 0.176 - 158 1 2 0 -0.0028 7 0 0 0 2.18E+07 2.18E+07 - - - 1.4062 0.9982 221125_WJC_METTL3_EV_vs_WT_F01.12436.12436.2 0.738 20-Aug K.LIADVAPSAIR.E "sp|P39748|FEN1_HUMAN,tr|F5H1Y3|F5H1Y3_HUMAN" 2 1124.6554 0.55 1965 12436 2 1124.653787 563.335 Flap endonuclease 1 OS=Homo sapiens OX=9606 GN=FEN1 PE=1 SV=1 5.84 2828.8 - 152958 - - - -1.3978 - 1.816 0.206 - 193.5 1 2 0 -0.0016 11 0 0 0 4.03E+07 7.31E+07 - - - 2.1761 0.9949 221125_WJC_METTL3_EV_vs_WT_F01.12439.12439.2 0.0488 16-Jul K.MLVVGGIDR.V sp|Q15046|SYK_HUMAN 1 958.527 1.08 1966 12439 2 958.525128 480.2708 Lysine--tRNA ligase OS=Homo sapiens OX=9606 GN=KARS1 PE=1 SV=3 5.59 2829.2 - 1.04E+06 - - - -1.9394 - 1.685 0.145 - 211.5 1 2 0 -0.0019 9 0 0 0 1.80E+08 1.66E+08 - - - 1.6209 0.9886 221125_WJC_METTL3_EV_vs_WT_F01.12454.12454.2 0.0358 14-Jul K.LTPVLLAK[136.11].Q "sp|Q13561|DCTN2_HUMAN,tr|H0YI98|H0YI98_HUMAN,tr|A8K8J9|A8K8J9_HUMAN,tr|F8W1I6|F8W1I6_HUMAN,tr|A0A7I2V4H4|A0A7I2V4H4_HUMAN,tr|A0A7I2V390|A0A7I2V390_HUMAN,tr|A0A7I2V4Y9|A0A7I2V4Y9_HUMAN,tr|F8VW18|F8VW18_HUMAN" 8 861.5779 2.81 1971 12454 2 861.574918 431.7962 Dynactin subunit 2 OS=Homo sapiens OX=9606 GN=DCTN2 PE=1 SV=4 8.75 2831.2 - 3.75E+06 - - - -3.4495 - 1.255 0.288 - 214.6 1 2 0 -0.003 8 0 0 0 6.95E+08 2.48E+08 - - - 1.8523 0.9897 221125_WJC_METTL3_EV_vs_WT_F01.12460.12460.2 0.334 16-Jul K.AFADPEVLR[166.11].R "sp|O75179|ANR17_HUMAN,sp|Q8IWZ3|ANKH1_HUMAN,tr|E9PDP5|E9PDP5_HUMAN,tr|H0YM23|H0YM23_HUMAN,tr|A0A1W2PQ15|A0A1W2PQ15_HUMAN" 5 1026.5374 2.47 1975 12460 2 1026.53773 514.276 Ankyrin repeat domain-containing protein 17 OS=Homo sapiens OX=9606 GN=ANKRD17 PE=1 SV=3 4.37 2832 - 866645 - - - 0.3556 - 1.128 0.197 - 89.5 3 2 0 0.0004 9 0 0 0 1.42E+08 5.76E+07 - - - 0.6313 0.9465 221125_WJC_METTL3_EV_vs_WT_F01.12467.12467.2 0.0915 12-Aug R.FASFIER[166.11].V sp|P07196|NFL_HUMAN 1 878.4526 1.9 1978 12467 2 878.447712 440.2336 Neurofilament light polypeptide OS=Homo sapiens OX=9606 GN=NEFL PE=1 SV=3 6 2833 - 271159 - - - -5.5336 - 1.423 0.221 - 182.1 1 2 0 -0.0049 7 0 0 0 1.72E+08 9.07E+07 - - - 1.7895 0.9101 221125_WJC_METTL3_EV_vs_WT_F01.12473.12473.2 0.966 12-May R.ELLASLR[166.11].R sp|Q13158|FADD_HUMAN 1 810.4839 1.37 1982 12473 2 810.482786 406.2492 FAS-associated death domain protein OS=Homo sapiens OX=9606 GN=FADD PE=1 SV=1 6.1 2833.6 - 781720 - - - -1.3412 - 1.088 0.074 - 73.5 11 2 0 -0.0011 7 0 0 0 4.19E+07 3.06E+07 - - - -0.6107 0.998 221125_WJC_METTL3_EV_vs_WT_F01.12480.12480.2 0.00729 12-Jun K.FEPTVFR[166.11].D "sp|Q9Y6E2|BZW2_HUMAN,tr|F8WDX8|F8WDX8_HUMAN,tr|E7EMS9|E7EMS9_HUMAN,tr|E9PFE3|E9PFE3_HUMAN,tr|E7ETZ4|E7ETZ4_HUMAN,tr|C9JF98|C9JF98_HUMAN,tr|Q75MG1|Q75MG1_HUMAN" 7 904.4682 1.1 1984 12480 2 904.467641 453.2414 Basic leucine zipper and W2 domain-containing protein 2 OS=Homo sapiens OX=9606 GN=BZW2 PE=1 SV=1 6 2834.7 - 375117 - - - -0.6435 - 1.191 0.306 - 131.3 1 2 0 -0.0006 7 0 0 0 1.98E+07 1.80E+07 - - - 1.8548 0.9752 221125_WJC_METTL3_EV_vs_WT_F01.12486.12486.2 0.948 14-Aug R.ALEGLVYR[166.11].S "sp|Q9Y4R8|TELO2_HUMAN,tr|H3BU45|H3BU45_HUMAN" 2 929.521 0.7 1986 12486 2 929.518949 465.7678 Telomere length regulation protein TEL2 homolog OS=Homo sapiens OX=9606 GN=TELO2 PE=1 SV=2 6.05 2835.5 - 438262 - - - -2.1925 - 1.247 0.122 - 245.9 1 2 0 -0.002 8 0 0 0 1.07E+07 1.52E+07 - - - 0.6072 0.9909 221125_WJC_METTL3_EV_vs_WT_F01.12491.12491.2 0.18 14-Jul K.LTPVLLAK.Q "sp|Q13561|DCTN2_HUMAN,tr|H0YI98|H0YI98_HUMAN,tr|A8K8J9|A8K8J9_HUMAN,tr|F8W1I6|F8W1I6_HUMAN,tr|A0A7I2V4H4|A0A7I2V4H4_HUMAN,tr|A0A7I2V390|A0A7I2V390_HUMAN,tr|A0A7I2V4Y9|A0A7I2V4Y9_HUMAN,tr|F8VW18|F8VW18_HUMAN" 8 853.5637 2.81 1987 12491 2 853.561159 427.7891 Dynactin subunit 2 OS=Homo sapiens OX=9606 GN=DCTN2 PE=1 SV=4 8.75 2836.2 - 1.66E+07 - - - -2.9652 - 1.158 0.307 - 132.4 1 2 0 -0.0025 8 0 0 0 6.95E+08 2.48E+08 - - - 1.7501 0.9637 221125_WJC_METTL3_EV_vs_WT_F01.12504.12504.2 3.76 12-May R.FSGVPDR.F "sp|A0A075B6R9|KVD24_HUMAN,sp|A0A0C4DH68|KV224_HUMAN,sp|A2NJV5|KV229_HUMAN,sp|A0A075B6S2|KVD29_HUMAN,sp|A0A0A0MRZ7|KVD26_HUMAN" 5 776.3817 570.17 1992 12504 2 776.38035 389.1981 Probable non-functional immunoglobulin kappa variable 2D-24 OS=Homo sapiens OX=9606 GN=IGKV2D-24 PE=1 SV=1 5.84 2838 - 1.80E+07 - - - -1.7427 - 1.147 0.109 - 74.6 2 2 0 -0.0014 7 0 0 0 1.23E+09 2.16E+06 - - - 0.1457 0.9801 221125_WJC_METTL3_EV_vs_WT_F01.12510.12510.2 0.0827 16-Aug R.ALGEEALLR[166.11].Y "sp|Q92503|S14L1_HUMAN,tr|K7EJ08|K7EJ08_HUMAN" 2 980.553 1.26 1994 12510 2 980.548812 491.2838 SEC14-like protein 1 OS=Homo sapiens OX=9606 GN=SEC14L1 PE=1 SV=2 4.53 2838.8 - 343566 - - - -4.2864 - 1.413 0.251 - 184.7 1 2 0 -0.0042 9 0 0 0 7.30E+06 5.77E+06 - - - 1.8937 0.9985 221125_WJC_METTL3_EV_vs_WT_F01.12522.12522.2 0.00318 14-Aug K.VVLVLAGR[166.11].Y "sp|P61353|RL27_HUMAN,tr|K7ERY7|K7ERY7_HUMAN,tr|K7EQQ9|K7EQQ9_HUMAN" 3 835.5519 0.83 1999 12522 2 835.549788 418.7832 60S ribosomal protein L27 OS=Homo sapiens OX=9606 GN=RPL27 PE=1 SV=2 9.72 2840.5 - 3.63E+06 - - - -2.5193 - 1.682 0.335 - 200.3 1 2 0 -0.0021 8 0 0 0 6.60E+08 7.95E+08 - - - 3.0829 0.9967 221125_WJC_METTL3_EV_vs_WT_F01.12530.12530.2 0.148 14-Aug K.VVLVLAGR.Y "sp|P61353|RL27_HUMAN,tr|K7ERY7|K7ERY7_HUMAN,tr|K7EQQ9|K7EQQ9_HUMAN" 3 825.5436 0.83 2003 12530 2 825.541281 413.7791 60S ribosomal protein L27 OS=Homo sapiens OX=9606 GN=RPL27 PE=1 SV=2 9.72 2841.5 - 4.09E+06 - - - -2.8369 - 1.428 0.329 - 308.3 1 2 0 -0.0023 8 0 0 0 6.60E+08 7.94E+08 - - - 2.5448 0.9953 221125_WJC_METTL3_EV_vs_WT_F01.12536.12536.2 0.0237 12-Aug K.VLEIPYK.G "sp|P48594|SPB4_HUMAN,sp|P29508|SPB3_HUMAN,tr|C9JZ65|C9JZ65_HUMAN,tr|H0Y5H9|H0Y5H9_HUMAN" 4 860.5008 100.89 2007 12536 2 860.499394 431.2577 Serpin B4 OS=Homo sapiens OX=9606 GN=SERPINB4 PE=1 SV=2 5.97 2842.2 - 916269 - - - -1.5816 - 1.47 0.168 - 233.7 1 2 0 -0.0014 7 0 0 0 2.83E+08 2.81E+06 - - - 1.5021 0.9993 221125_WJC_METTL3_EV_vs_WT_F01.12544.12544.2 0.00198 14-Aug R.IFNTFGPR.M "sp|Q8NBZ7|UXS1_HUMAN,tr|C9JCB7|C9JCB7_HUMAN,tr|C9JFU6|C9JFU6_HUMAN,tr|C9JE50|C9JE50_HUMAN" 4 950.4974 1.6 2013 12544 2 950.496874 476.256 UDP-glucuronic acid decarboxylase 1 OS=Homo sapiens OX=9606 GN=UXS1 PE=1 SV=1 9.75 2843.2 - 993961 - - - -0.5544 - 1.523 0.33 - 170.6 1 2 0 -0.0005 8 0 0 0 4.35E+07 2.71E+07 - - - 2.747 0.9978 221125_WJC_METTL3_EV_vs_WT_F01.12545.12545.2 0.0182 12-Jul K.ILMEFNK.M sp|Q9UQE7|SMC3_HUMAN 1 893.4681 0.86 2014 12545 2 893.466404 447.7413 Structural maintenance of chromosomes protein 3 OS=Homo sapiens OX=9606 GN=SMC3 PE=1 SV=2 6 2843.3 - 606652 - - - -1.8702 - 1.366 0.303 - 125.2 1 2 0 -0.0017 7 0 0 0 4.81E+07 5.60E+07 - - - 2.2667 0.9814 221125_WJC_METTL3_EV_vs_WT_F01.12550.12550.2 0.619 12-May K.ILMEFNK[136.11].M sp|Q9UQE7|SMC3_HUMAN 1 901.4823 0.86 2017 12550 2 901.481275 451.7484 Structural maintenance of chromosomes protein 3 OS=Homo sapiens OX=9606 GN=SMC3 PE=1 SV=2 6 2843.9 - 1.21E+06 - - - -1.1093 - 1.102 0.136 - 53 1 2 0 -0.001 7 0 0 0 4.80E+07 5.60E+07 - - - 0.3529 0.9984 221125_WJC_METTL3_EV_vs_WT_F01.12559.12559.2 0.256 18-Aug R.LGLMPPPEPK.V sp|O43395|PRPF3_HUMAN 1 1077.5893 2.78 2022 12559 2 1077.588936 539.8019 U4\U6 small nuclear ribonucleoprotein Prp3 OS=Homo sapiens OX=9606 GN=PRPF3 PE=1 SV=2 6 2845.1 - 206882 - - - -0.2942 - 1.421 0.264 - 147.8 1 2 0 -0.0003 10 0 0 0 9.57E+06 3.45E+06 - - - 1.9716 0.9989 221125_WJC_METTL3_EV_vs_WT_F01.12560.12560.2 0.00733 26-Aug R.LVPGGGATEIELAK[136.11].Q sp|P50990|TCPQ_HUMAN 1 1361.7646 0.39 2023 12560 2 1361.765133 681.8896 T-complex protein 1 subunit theta OS=Homo sapiens OX=9606 GN=CCT8 PE=1 SV=4 4.53 2845.3 - 134963 - - - 0.4054 - 1.292 0.364 - 123.5 1 2 0 0.0006 14 0 0 0 3.80E+06 9.79E+06 - - - 2.3722 0.9981 221125_WJC_METTL3_EV_vs_WT_F01.12563.12563.2 0.0159 12-Jun R.FPPYYMR[166.11].R "sp|P67809|YBOX1_HUMAN,tr|H0Y449|H0Y449_HUMAN,tr|C9J5V9|C9J5V9_HUMAN" 3 982.461 0.97 2024 12563 2 982.460164 492.2378 Y-box-binding protein 1 OS=Homo sapiens OX=9606 GN=YBX1 PE=1 SV=3 8.59 2845.7 - 243582 - - - -0.8804 - 1.074 0.362 - 124.3 1 2 0 -0.0009 7 0 0 0 1.34E+07 1.39E+07 - - - 1.9407 0.9848 221125_WJC_METTL3_EV_vs_WT_F01.12566.12566.2 0.376 12-Jun K.AVFLVPK[136.11].W sp|Q9H2M9|RBGPR_HUMAN 1 780.4989 0.9 2025 12566 2 780.499379 391.2567 Rab3 GTPase-activating protein non-catalytic subunit OS=Homo sapiens OX=9606 GN=RAB3GAP2 PE=1 SV=1 8.8 2846.1 - 794219 - - - 0.5996 - 1.098 0.146 - 160.6 1 2 0 0.0005 7 0 0 0 1.57E+07 1.75E+07 - - - 0.4154 0.9952 221125_WJC_METTL3_EV_vs_WT_F01.12572.12572.2 0.00111 12-Jul R.GFLAEMK.R "sp|A6ZKI3|RTL8C_HUMAN,sp|Q9BWD3|RTL8A_HUMAN,sp|Q17RB0|RTL8B_HUMAN" 3 794.3997 1.07 2029 12572 2 794.396618 398.2071 Retrotransposon Gag-like protein 8C OS=Homo sapiens OX=9606 GN=RTL8C PE=1 SV=1 6 2846.9 - 313330 - - - -3.8306 - 1.354 0.388 - 133.6 1 2 0 -0.003 7 0 0 0 3.25E+07 3.03E+07 - - - 2.8661 0.9953 221125_WJC_METTL3_EV_vs_WT_F01.12584.12584.2 2 14-Sep K.IADFGLAR[166.11].L "sp|P07947|YES_HUMAN,sp|P51451|BLK_HUMAN,sp|Q9UPZ9|CILK1_HUMAN,sp|Q00537|CDK17_HUMAN,sp|P24941|CDK2_HUMAN,sp|P50750|CDK9_HUMAN,sp|Q07002|CDK18_HUMAN,sp|P22455|FGFR4_HUMAN,sp|Q00526|CDK3_HUMAN,sp|Q9NYV4|CDK12_HUMAN,sp|Q00534|CDK6_HUMAN,sp|P11802|CDK4_HUMAN,sp|Q00536|CDK16_HUMAN,sp|P09769|FGR_HUMAN,sp|P06239|LCK_HUMAN,sp|P20794|MAK_HUMAN,sp|P07948|LYN_HUMAN,sp|P06493|CDK1_HUMAN,sp|Q14004|CDK13_HUMAN,sp|P11362|FGFR1_HUMAN,sp|O94921|CDK14_HUMAN,sp|P08631|HCK_HUMAN,sp|Q00535|CDK5_HUMAN,sp|P06241|FYN_HUMAN,sp|P21802|FGFR2_HUMAN,sp|Q96Q40|CDK15_HUMAN,sp|P22607|FGFR3_HUMAN,sp|Q8IZL9|CDK20_HUMAN,tr|D2CGD1|D2CGD1_HUMAN,tr|A0A3B3ISD1|A0A3B3ISD1_HUMAN,tr|A0A0S2Z3T4|A0A0S2Z3T4_HUMAN,tr|A0A6Q8PG01|A0A6Q8PG01_HUMAN,tr|J3QSD7|J3QSD7_HUMAN,tr|Q573B4|Q573B4_HUMAN,tr|E9PJX5|E9PJX5_HUMAN,tr|E5RIU6|E5RIU6_HUMAN,tr|H0YE20|H0YE20_HUMAN,tr|E7EVR7|E7EVR7_HUMAN,tr|H0Y3C5|H0Y3C5_HUMAN,tr|A0A2R8Y4Z0|A0A2R8Y4Z0_HUMAN,tr|G3V5T9|G3V5T9_HUMAN,tr|F8VWX7|F8VWX7_HUMAN,tr|A0A2R8YD28|A0A2R8YD28_HUMAN,tr|F5H6Z0|F5H6Z0_HUMAN,tr|J3KPD6|J3KPD6_HUMAN,tr|F8VXD2|F8VXD2_HUMAN,tr|A0A2R8YEB7|A0A2R8YEB7_HUMAN,tr|S4R381|S4R381_HUMAN,tr|Q9BVE2|Q9BVE2_HUMAN,tr|A0A804HIF1|A0A804HIF1_HUMAN,tr|E5RGN0|E5RGN0_HUMAN,tr|A0A2R8YF61|A0A2R8YF61_HUMAN,tr|A0A087X209|A0A087X209_HUMAN,tr|E7EUK8|E7EUK8_HUMAN,tr|E7ESI2|E7ESI2_HUMAN,tr|K7EJ83|K7EJ83_HUMAN,tr|A0A1W2PQT9|A0A1W2PQT9_HUMAN,tr|H7BXU9|H7BXU9_HUMAN,tr|A0A024QZP7|A0A024QZP7_HUMAN,tr|Q8IXN4|Q8IXN4_HUMAN,tr|A0A087WZZ9|A0A087WZZ9_HUMAN,tr|A0A7I2PIU1|A0A7I2PIU1_HUMAN,tr|H0Y9P2|H0Y9P2_HUMAN,tr|A0A7I2RW32|A0A7I2RW32_HUMAN,tr|A0A0A0MR25|A0A0A0MR25_HUMAN,tr|F8VZZ0|F8VZZ0_HUMAN,tr|J3QRU1|J3QRU1_HUMAN,tr|F8VTV8|F8VTV8_HUMAN,tr|H7C265|H7C265_HUMAN,tr|E7EU09|E7EU09_HUMAN,tr|A0A2R8Y7W5|A0A2R8Y7W5_HUMAN,tr|H0YAZ9|H0YAZ9_HUMAN,tr|F8VYH9|F8VYH9_HUMAN,tr|A0A2R8Y644|A0A2R8Y644_HUMAN,tr|A0A804HI76|A0A804HI76_HUMAN,tr|F8W9L4|F8W9L4_HUMAN,tr|A0A5S6RJB7|A0A5S6RJB7_HUMAN,tr|F8VZ51|F8VZ51_HUMAN,tr|A0A087WZU2|A0A087WZU2_HUMAN,tr|A0A6Q8PH30|A0A6Q8PH30_HUMAN,tr|J3KPQ0|J3KPQ0_HUMAN" 81 871.4791 0.67 2035 12584 2 871.479212 436.7468 Tyrosine-protein kinase Yes OS=Homo sapiens OX=9606 GN=YES1 PE=1 SV=3 5.84 2848.6 - 1.19E+06 - - - 0.1033 - 1.548 0.107 - 222.8 1 2 0 0.0001 8 0 0 0 4.37E+07 6.54E+07 - - - 1.1491 0.9975 221125_WJC_METTL3_EV_vs_WT_F01.12604.12604.2 0.122 14-Sep K.IGDFGLAR.D "sp|P08922|ROS1_HUMAN,sp|P07333|CSF1R_HUMAN,sp|P51617|IRAK1_HUMAN,sp|Q96PY6|NEK1_HUMAN,sp|P51955|NEK2_HUMAN,sp|Q6P3R8|NEK5_HUMAN,sp|Q16659|MK06_HUMAN,sp|P31152|MK04_HUMAN,tr|E9PIX7|E9PIX7_HUMAN,tr|H7C2I6|H7C2I6_HUMAN,tr|K7EN18|K7EN18_HUMAN,tr|A0A494C168|A0A494C168_HUMAN,tr|F6U4U2|F6U4U2_HUMAN,tr|H7C224|H7C224_HUMAN,tr|K7ELV1|K7ELV1_HUMAN,tr|Q5H8Y1|Q5H8Y1_HUMAN,tr|A0A3B3ITQ6|A0A3B3ITQ6_HUMAN,tr|D3YTB5|D3YTB5_HUMAN" 18 847.4552 1.43 2045 12604 2 847.45375 424.7349 Proto-oncogene tyrosine-protein kinase ROS OS=Homo sapiens OX=9606 GN=ROS1 PE=1 SV=3 5.84 2851.2 - 984700 - - - -1.7134 - 2.038 0.121 - 248.8 1 2 0 -0.0015 8 0 0 0 8.91E+07 6.21E+07 - - - 2.0815 0.8963 221125_WJC_METTL3_EV_vs_WT_F01.12606.12606.2 0.0517 14-Sep E.ILNPLVSK.A "sp|Q6NUP7|PP4R4_HUMAN,sp|Q9BSC4|NOL10_HUMAN,tr|G3V431|G3V431_HUMAN" 3 882.5539 1.13 2047 12606 2 882.553038 442.2842 Serine\threonine-protein phosphatase 4 regulatory subunit 4 OS=Homo sapiens OX=9606 GN=PPP4R4 PE=1 SV=1 8.75 2851.4 - 1.90E+06 - - - -0.9246 - 1.426 0.248 - 198.8 1 1 0 -0.0008 8 0 0 0 8.53E+07 7.52E+07 - - - 1.9428 0.9998 221125_WJC_METTL3_EV_vs_WT_F01.12607.12607.2 0.000304 18-Oct R.LAEVALAYAK.A sp|P13716|HEM2_HUMAN 1 1047.5964 19.65 2048 12607 2 1047.595863 524.8055 Delta-aminolevulinic acid dehydratase OS=Homo sapiens OX=9606 GN=ALAD PE=1 SV=1 6 2851.5 - 497236 - - - -0.5575 - 2.263 0.345 - 271 1 2 0 -0.0006 10 0 0 0 2.07E+07 1.06E+06 - - - 3.8686 0.8276 221125_WJC_METTL3_EV_vs_WT_F01.12609.12609.2 1.7 26-May R.LVPGGGATEIELAK.Q sp|P50990|TCPQ_HUMAN 1 1353.7504 0.39 2050 12609 2 1353.74805 677.8825 T-complex protein 1 subunit theta OS=Homo sapiens OX=9606 GN=CCT8 PE=1 SV=4 4.53 2851.8 - 76460.3 - - - -1.7219 - 0.981 0.04 - 26.9 3 2 0 -0.0023 14 0 0 0 3.80E+06 9.75E+06 - - - -0.9256 1 221125_WJC_METTL3_EV_vs_WT_F01.12623.12623.4 0.0111 10/198 R.SDSPVPTAPTSGGPK[136.11]PSTASAVPELATDPELEK[136.11]K[136.11].L "sp|Q86U44|MTA70_HUMAN,tr|B4E349|B4E349_HUMAN,tr|F5H6D8|F5H6D8_HUMAN,tr|B4DTN4|B4DTN4_HUMAN" 4 3384.7363 0.001 2057 12623 4 3384.73113 847.1913 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 4.51 2853.6 - 287721 - - - -1.5159 - 2.335 0.526 - 39.5 1 2 0 -0.0051 34 0 0 0 0.00E+00 8.19E+06 - - - 4.0558 0.9376 221125_WJC_METTL3_EV_vs_WT_F01.12628.12628.2 0.103 14-Aug R.ILFR[166.11]PVAS.Q "sp|P35232|PHB_HUMAN,tr|C9JZ20|C9JZ20_HUMAN,tr|E7ESE2|E7ESE2_HUMAN,tr|E9PCW0|E9PCW0_HUMAN,tr|C9JW96|C9JW96_HUMAN" 5 911.5468 1.31 2060 12628 2 911.545948 456.7807 Prohibitin OS=Homo sapiens OX=9606 GN=PHB PE=1 SV=1 9.75 2854.1 - 1.43E+06 - - - -0.9435 - 1.449 0.306 - 124.2 1 1 0 -0.0009 8 0 0 0 5.18E+07 3.96E+07 - - - 2.4194 0.9987 221125_WJC_METTL3_EV_vs_WT_F01.12634.12634.2 0.211 14-Sep K.IGDFGLAR[166.11].D "sp|P08922|ROS1_HUMAN,sp|P07333|CSF1R_HUMAN,sp|P51617|IRAK1_HUMAN,sp|Q96PY6|NEK1_HUMAN,sp|P51955|NEK2_HUMAN,sp|Q6P3R8|NEK5_HUMAN,sp|Q16659|MK06_HUMAN,sp|P31152|MK04_HUMAN,tr|E9PIX7|E9PIX7_HUMAN,tr|H7C2I6|H7C2I6_HUMAN,tr|K7EN18|K7EN18_HUMAN,tr|A0A494C168|A0A494C168_HUMAN,tr|F6U4U2|F6U4U2_HUMAN,tr|H7C224|H7C224_HUMAN,tr|K7ELV1|K7ELV1_HUMAN,tr|Q5H8Y1|Q5H8Y1_HUMAN,tr|A0A3B3ITQ6|A0A3B3ITQ6_HUMAN,tr|D3YTB5|D3YTB5_HUMAN" 18 857.4635 1.44 2064 12634 2 857.463247 429.739 Proto-oncogene tyrosine-protein kinase ROS OS=Homo sapiens OX=9606 GN=ROS1 PE=1 SV=3 5.84 2854.8 - 2.18E+06 - - - -0.2624 - 2.132 0.11 - 246 1 2 0 -0.0002 8 0 0 0 8.65E+07 6.01E+07 - - - 2.1366 0.999 221125_WJC_METTL3_EV_vs_WT_F01.12641.12641.2 0.0236 14-Aug K.VVNPLFEK[136.11].R "sp|P62424|RL7A_HUMAN,tr|Q5T8U3|Q5T8U3_HUMAN" 2 952.5473 1.02 2067 12641 2 952.54661 477.2809 60S ribosomal protein L7a OS=Homo sapiens OX=9606 GN=RPL7A PE=1 SV=2 5.97 2855.7 - 718524 - - - -0.7433 - 1.506 0.294 - 203.8 1 2 0 -0.0007 8 0 0 0 3.45E+07 3.38E+07 - - - 2.4472 0.8923 221125_WJC_METTL3_EV_vs_WT_F01.12646.12646.2 0.215 14-Jul R.ILFRPVAS.Q "sp|P35232|PHB_HUMAN,tr|C9JZ20|C9JZ20_HUMAN,tr|E7ESE2|E7ESE2_HUMAN,tr|E9PCW0|E9PCW0_HUMAN,tr|C9JW96|C9JW96_HUMAN" 5 901.5385 1.26 2070 12646 2 901.537795 451.7765 Prohibitin OS=Homo sapiens OX=9606 GN=PHB PE=1 SV=1 9.75 2856.3 - 1.33E+06 - - - -0.8241 - 1.363 0.258 - 100.5 1 1 0 -0.0007 8 0 0 0 5.18E+07 4.11E+07 - - - 1.8804 0.9547 221125_WJC_METTL3_EV_vs_WT_F01.12651.12651.2 0.895 12-Jun R.FPPYYMR.R "sp|P67809|YBOX1_HUMAN,tr|H0Y449|H0Y449_HUMAN,tr|C9J5V9|C9J5V9_HUMAN" 3 972.4528 0.94 2073 12651 2 972.453937 487.2337 Y-box-binding protein 1 OS=Homo sapiens OX=9606 GN=YBX1 PE=1 SV=3 8.59 2856.8 - 186224 - - - 1.2114 - 0.945 0.136 - 132.4 1 2 0 0.0012 7 0 0 0 1.45E+07 1.54E+07 - - - -0.1341 0.9989 221125_WJC_METTL3_EV_vs_WT_F01.12655.12655.2 0.121 16-Aug R.ILVLNGGYR[166.11].G "sp|O60870|KIN17_HUMAN,tr|S4R357|S4R357_HUMAN" 2 1013.5897 0.67 2075 12655 2 1013.590456 507.8021 DNA\RNA-binding protein KIN17 OS=Homo sapiens OX=9606 GN=KIN PE=1 SV=2 8.75 2857.3 - 860834 - - - 0.7113 - 1.816 0.219 - 149.2 1 2 0 0.0007 9 0 0 0 1.70E+07 2.53E+07 - - - 2.3844 0.9807 221125_WJC_METTL3_EV_vs_WT_F01.12663.12663.2 0.292 14-Aug K.INELLLAK.E "sp|Q8IWJ2|GCC2_HUMAN,tr|B8ZZW2|B8ZZW2_HUMAN" 2 912.5644 2.33 2081 12663 2 912.567482 457.2895 GRIP and coiled-coil domain-containing protein 2 OS=Homo sapiens OX=9606 GN=GCC2 PE=1 SV=4 6 2858.4 - 707973 - - - 3.3576 - 1.544 0.143 - 100.7 1 2 0 0.0031 8 0 0 0 4.33E+07 1.86E+07 - - - 1.4063 0.9969 221125_WJC_METTL3_EV_vs_WT_F01.12664.12664.3 0.00013 Dec-40 K.FAAQELIEVK[136.11]R[166.11].G "sp|Q86U44|MTA70_HUMAN,tr|F5H6D8|F5H6D8_HUMAN,tr|H0YFV6|H0YFV6_HUMAN,tr|B4DTN4|B4DTN4_HUMAN" 4 1320.7521 0.14 2082 12664 3 1320.753205 441.258 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 6.14 2858.4 - 1.52E+06 - - - 0.87 - 2.208 0.16 - 140.9 1 2 0 0.0011 11 0 0 0 4.59E+06 3.30E+07 - - - 2.5737 0.9346 221125_WJC_METTL3_EV_vs_WT_F01.12665.12665.2 3.27 12-Apr R.IGLLDPR[166.11].W "sp|Q15459|SF3A1_HUMAN,tr|H7C1L2|H7C1L2_HUMAN" 2 792.4733 0.94 2083 12665 2 792.472176 397.2439 Splicing factor 3A subunit 1 OS=Homo sapiens OX=9606 GN=SF3A1 PE=1 SV=1 5.84 2858.6 - 442414 - - - -1.4284 - 1.01 0.076 - 58 1 2 0 -0.0011 7 0 0 0 1.97E+08 2.09E+08 - - - -0.3665 0.9995 221125_WJC_METTL3_EV_vs_WT_F01.12675.12675.2 3.91E-06 14-Sep -.MFAPAVMR.A sp|Q9P0S2|COX16_HUMAN 1 921.4565 1.48 2091 12675 2 921.457027 461.7355 "Cytochrome c oxidase assembly protein COX16 homolog, mitochondrial OS=Homo sapiens OX=9606 GN=COX16 PE=1 SV=1" 9.5 2859.8 - 1.14E+06 - - - 0.611 - 1.689 0.34 - 291 1 2 0 0.0006 8 0 0 0 5.43E+07 3.68E+07 - - - 3.1328 0.9984 221125_WJC_METTL3_EV_vs_WT_F01.12676.12676.2 0.108 14-Jun R.VAELLLAK.A sp|Q5T6V5|QSPP_HUMAN 1 855.543 0.58 2092 12676 2 855.543335 428.7788 Queuosine salvage protein OS=Homo sapiens OX=9606 GN=C9orf64 PE=1 SV=1 5.97 2859.9 - 1.09E+06 - - - 0.4453 - 1.361 0.282 - 106.4 1 2 0 0.0004 8 0 0 0 2.47E+07 4.29E+07 - - - 2.0533 0.9912 221125_WJC_METTL3_EV_vs_WT_F01.12686.12686.2 0.511 12-Jun R.LALEELR.S sp|Q99496|RING2_HUMAN 1 842.4862 1.38 2100 12686 2 842.485556 422.2504 E3 ubiquitin-protein ligase RING2 OS=Homo sapiens OX=9606 GN=RNF2 PE=1 SV=1 4.53 2861.1 - 1.18E+06 - - - -0.7264 - 1.34 0.107 - 125 1 2 0 -0.0006 7 0 0 0 3.08E+08 2.24E+08 - - - 0.7585 0.9941 221125_WJC_METTL3_EV_vs_WT_F01.12693.12693.2 0.339 14-Jun K.VLPITVPK[136.11].S sp|Q9ULW0|TPX2_HUMAN 1 873.5779 0.65 2105 12693 2 873.57805 437.7962 Targeting protein for Xklp2 OS=Homo sapiens OX=9606 GN=TPX2 PE=1 SV=2 8.72 2862 - 389316 - - - 0.1832 - 1.109 0.223 - 79.6 1 2 0 0.0002 8 0 0 0 2.56E+07 3.93E+07 - - - 1.0001 0.9995 221125_WJC_METTL3_EV_vs_WT_F01.12698.12698.2 1.17E-05 14-Sep -.MFAPAVMR[166.11].A sp|Q9P0S2|COX16_HUMAN 1 931.4647 1.47 2107 12698 2 931.464758 466.7396 "Cytochrome c oxidase assembly protein COX16 homolog, mitochondrial OS=Homo sapiens OX=9606 GN=COX16 PE=1 SV=1" 9.5 2862.7 - 1.46E+06 - - - 0.0258 - 1.85 0.28 - 360.7 1 2 0 0 8 0 0 0 5.41E+07 3.68E+07 - - - 2.9644 0.9954 221125_WJC_METTL3_EV_vs_WT_F01.12699.12699.2 0.134 14-Jul R.LFVGSIPK[136.11].S "sp|O60506|HNRPQ_HUMAN,sp|O43390|HNRPR_HUMAN,tr|A0A7I2YQV8|A0A7I2YQV8_HUMAN,tr|B4DT28|B4DT28_HUMAN,tr|A0A7I2YQN2|A0A7I2YQN2_HUMAN,tr|A0A7I2V5Q6|A0A7I2V5Q6_HUMAN,tr|A0A7I2V4Z0|A0A7I2V4Z0_HUMAN,tr|A0A6Q8PHG0|A0A6Q8PHG0_HUMAN,tr|B7Z645|B7Z645_HUMAN,tr|A0A6Q8PH31|A0A6Q8PH31_HUMAN,tr|A0A6Q8PEX7|A0A6Q8PEX7_HUMAN,tr|A0A7I2V2F2|A0A7I2V2F2_HUMAN,tr|A0A7I2V346|A0A7I2V346_HUMAN,tr|A0A7I2V309|A0A7I2V309_HUMAN" 14 867.5309 1.22 2108 12699 2 867.530569 434.7727 Heterogeneous nuclear ribonucleoprotein Q OS=Homo sapiens OX=9606 GN=SYNCRIP PE=1 SV=2 8.75 2862.8 - 769358 - - - -0.4277 - 1.252 0.196 - 138.6 1 2 0 -0.0004 8 0 0 0 9.21E+08 7.54E+08 - - - 1.1664 0.986 221125_WJC_METTL3_EV_vs_WT_F01.12705.12705.2 0.12 14-Jun K.LLTLVSTR.D "sp|Q9NRL2|BAZ1A_HUMAN,tr|A0A087WWN7|A0A087WWN7_HUMAN" 2 901.5597 0.49 2112 12705 2 901.559315 451.7871 Bromodomain adjacent to zinc finger domain protein 1A OS=Homo sapiens OX=9606 GN=BAZ1A PE=1 SV=2 9.75 2863.6 - 681640 - - - -0.3904 - 1.402 0.064 - 83.7 2 2 0 -0.0004 8 0 0 0 1.84E+07 3.76E+07 - - - 0.3982 0.9989 221125_WJC_METTL3_EV_vs_WT_F01.12706.12706.2 0.0021 14-Sep K.LALDYGIK.F "sp|P61006|RAB8A_HUMAN,sp|Q92930|RAB8B_HUMAN,tr|H0YNE9|H0YNE9_HUMAN" 3 891.5066 0.74 2113 12706 2 891.505164 446.7606 Ras-related protein Rab-8A OS=Homo sapiens OX=9606 GN=RAB8A PE=1 SV=1 5.83 2863.7 - 553840 - - - -1.576 - 1.743 0.27 - 192.5 1 2 0 -0.0014 8 0 0 0 2.03E+07 2.74E+07 - - - 2.7105 0.8082 221125_WJC_METTL3_EV_vs_WT_F01.12711.12711.2 0.363 16-Jun K.LPIGDVATQ.Y sp|Q99832|TCPH_HUMAN 1 912.4916 - 2116 12711 2 912.491345 457.2531 T-complex protein 1 subunit eta OS=Homo sapiens OX=9606 GN=CCT7 PE=1 SV=2 3.8 2864.4 - 2.04E+06 - - - -0.331 - 1.186 0.236 - 81 1 1 0 -0.0003 9 0 0 0 - - - - - 1.2775 0.9968 221125_WJC_METTL3_EV_vs_WT_F01.12712.12712.2 1.48 14-Aug K.LALDYGIK[136.11].F "sp|P61006|RAB8A_HUMAN,sp|Q92930|RAB8B_HUMAN,tr|H0YNE9|H0YNE9_HUMAN" 3 899.5208 0.89 2117 12712 2 899.519651 450.7677 Ras-related protein Rab-8A OS=Homo sapiens OX=9606 GN=RAB8A PE=1 SV=1 5.83 2864.5 - 761908 - - - -1.2429 - 1.546 0.177 - 146.3 1 2 0 -0.0011 8 0 0 0 2.02E+07 2.28E+07 - - - 1.6619 0.9105 221125_WJC_METTL3_EV_vs_WT_F01.12716.12716.2 0.485 16-Jul H.VVVLVATVR[166.11].A "sp|P11586|C1TC_HUMAN,sp|Q6UB35|C1TM_HUMAN,tr|A0A087WVM4|A0A087WVM4_HUMAN,tr|B7ZM99|B7ZM99_HUMAN,tr|F5H2F4|F5H2F4_HUMAN,tr|V9GZ78|V9GZ78_HUMAN,tr|V9GYY3|V9GYY3_HUMAN,tr|A0A494C1T2|A0A494C1T2_HUMAN" 8 964.6309 1.23 2119 12716 2 964.630446 483.3227 "C-1-tetrahydrofolate synthase, cytoplasmic OS=Homo sapiens OX=9606 GN=MTHFD1 PE=1 SV=4" 9.72 2865.1 - 193642 - - - -0.4416 - 1.858 0.196 - 136.5 5 1 0 -0.0004 9 0 0 0 1.08E+07 8.78E+06 - - - 1.9685 0.9994 221125_WJC_METTL3_EV_vs_WT_F01.12723.12723.2 0.00121 14-Sep R.LLAAFEER.E "sp|Q9HC52|CBX8_HUMAN,tr|C9J6K3|C9J6K3_HUMAN,tr|C9JM54|C9JM54_HUMAN" 3 947.5076 1.73 2124 12723 2 947.50727 474.7611 Chromobox protein homolog 8 OS=Homo sapiens OX=9606 GN=CBX8 PE=1 SV=3 4.53 2865.9 - 909178 - - - -0.3821 - 1.863 0.261 - 294.4 1 2 0 -0.0004 8 0 0 0 1.28E+08 7.42E+07 - - - 2.8451 0.9936 221125_WJC_METTL3_EV_vs_WT_F01.12732.12732.2 0.831 12-Jul K.SVIISIK.G "sp|Q0IIM8|TBC8B_HUMAN,sp|P09496|CLCA_HUMAN,tr|J3KN75|J3KN75_HUMAN,tr|C9J8P9|C9J8P9_HUMAN,tr|D6RFZ2|D6RFZ2_HUMAN" 5 758.4902 0.38 2129 12732 2 758.489673 380.2524 TBC1 domain family member 8B OS=Homo sapiens OX=9606 GN=TBC1D8B PE=1 SV=2 8.47 2867.1 - 711651 - - - -0.6829 - 1.314 0.144 - 182.9 1 2 0 -0.0005 7 0 0 0 5.25E+07 1.37E+08 - - - 0.9697 0.9757 221125_WJC_METTL3_EV_vs_WT_F01.12749.12749.2 1.21 12-Jun K.YGVDLIR.Y sp|Q6UXN9|WDR82_HUMAN 1 834.46 0.61 2137 12749 2 834.460521 418.2373 WD repeat-containing protein 82 OS=Homo sapiens OX=9606 GN=WDR82 PE=1 SV=1 5.84 2869.5 - 1.70E+06 - - - 0.6807 - 1.187 0.073 - 97.1 1 2 0 0.0006 7 0 0 0 6.19E+07 1.02E+08 - - - 0.1232 0.9557 221125_WJC_METTL3_EV_vs_WT_F01.12750.12750.2 1.1 12-May K.FIPLYSK[136.11].V "sp|Q14694|UBP10_HUMAN,tr|J3KT19|J3KT19_HUMAN,tr|H3BVF1|H3BVF1_HUMAN" 3 874.5044 0.82 2138 12750 2 874.503035 438.2595 Ubiquitin carboxyl-terminal hydrolase 10 OS=Homo sapiens OX=9606 GN=USP10 PE=1 SV=2 8.59 2869.6 - 1.23E+06 - - - -1.5506 - 0.95 0.172 - 68.9 3 2 0 -0.0014 7 0 0 0 4.20E+07 5.11E+07 - - - -0.0647 0.9778 221125_WJC_METTL3_EV_vs_WT_F01.12752.12752.2 1.01 16-Jun K.TLGTGSFGR[166.11].V "sp|P22694|KAPCB_HUMAN,sp|P17612|KAPCA_HUMAN,tr|B1APF9|B1APF9_HUMAN,tr|B1APG0|B1APG0_HUMAN,tr|A0A087WVC4|A0A087WVC4_HUMAN,tr|B1APG2|B1APG2_HUMAN,tr|B1APF7|B1APF7_HUMAN,tr|Q15136|Q15136_HUMAN,tr|B1APF8|B1APF8_HUMAN,tr|B1APG1|B1APG1_HUMAN,tr|B1APG3|B1APG3_HUMAN,tr|K7ERP6|K7ERP6_HUMAN,tr|A0A0A0MS54|A0A0A0MS54_HUMAN" 13 904.4642 1.61 2140 12752 2 904.465298 453.2394 cAMP-dependent protein kinase catalytic subunit beta OS=Homo sapiens OX=9606 GN=PRKACB PE=1 SV=2 9.41 2869.8 - 277365 - - - 1.214 - 1.079 0.146 - 68.8 1 2 0 0.0011 9 0 0 0 4.76E+07 2.95E+07 - - - 0.339 0.9838 221125_WJC_METTL3_EV_vs_WT_F01.12758.12758.2 0.387 14-May R.ALNGLLYK[136.11].A "sp|Q8N0V3|RBFA_HUMAN,tr|K7EIS1|K7EIS1_HUMAN" 2 898.5368 0.78 2143 12758 2 898.535552 450.2757 "Putative ribosome-binding factor A, mitochondrial OS=Homo sapiens OX=9606 GN=RBFA PE=1 SV=3" 8.63 2870.7 - 465157 - - - -1.3366 - 1.173 0.154 - 52.3 2 2 0 -0.0012 8 0 0 0 2.00E+07 2.57E+07 - - - 0.5248 0.9867 221125_WJC_METTL3_EV_vs_WT_F01.12760.12760.2 0.137 20-Jun K.YGQISEVVVVK.D "sp|Q14011|CIRBP_HUMAN,tr|K7ER40|K7ER40_HUMAN,tr|K7ENX8|K7ENX8_HUMAN,tr|K7EJV1|K7EJV1_HUMAN,tr|K7EJV5|K7EJV5_HUMAN,tr|K7ELT6|K7ELT6_HUMAN,tr|K7EMY9|K7EMY9_HUMAN,tr|K7ELV6|K7ELV6_HUMAN,tr|K7EQR7|K7EQR7_HUMAN,tr|K7EPM4|K7EPM4_HUMAN,tr|D6W5Y5|D6W5Y5_HUMAN" 11 1219.6812 0.97 2145 12760 2 1219.682777 610.8479 Cold-inducible RNA-binding protein OS=Homo sapiens OX=9606 GN=CIRBP PE=1 SV=1 6 2871 - 87385.5 - - - 1.261 - 1.048 0.208 - 84.4 1 2 0 0.0015 11 0 0 0 1.95E+06 2.02E+06 - - - 0.7036 0.9923 221125_WJC_METTL3_EV_vs_WT_F01.12770.12770.2 4.17E-05 16-Nov K.PGTYVIYVR[166.11].F "sp|O75369|FLNB_HUMAN,tr|E7EN95|E7EN95_HUMAN,tr|A0A804HK76|A0A804HK76_HUMAN,tr|A0A804HL72|A0A804HL72_HUMAN" 4 1076.5894 0.84 2151 12770 2 1076.588914 539.302 Filamin-B OS=Homo sapiens OX=9606 GN=FLNB PE=1 SV=2 9 2872.2 - 160411 - - - -0.4524 - 2.253 0.457 - 422.7 1 1 0 -0.0005 9 0 0 0 7.55E+06 8.97E+06 - - - 4.7662 0.9994 221125_WJC_METTL3_EV_vs_WT_F01.12773.12773.2 0.0372 14-Aug R.LLAAFEER[166.11].E "sp|Q9HC52|CBX8_HUMAN,tr|C9J6K3|C9J6K3_HUMAN,tr|C9JM54|C9JM54_HUMAN" 3 957.5159 1.78 2153 12773 2 957.515405 479.7652 Chromobox protein homolog 8 OS=Homo sapiens OX=9606 GN=CBX8 PE=1 SV=3 4.53 2872.5 - 2.02E+06 - - - -0.5191 - 1.518 0.355 - 196.9 1 2 0 -0.0005 8 0 0 0 1.28E+08 7.21E+07 - - - 2.9217 0.995 221125_WJC_METTL3_EV_vs_WT_F01.12776.12776.2 0.158 12-Jul R.NLPMHLR.R "sp|Q9P2E3|ZNFX1_HUMAN,tr|Q5JXR6|Q5JXR6_HUMAN,tr|Q5JXR7|Q5JXR7_HUMAN,tr|Q5JXR5|Q5JXR5_HUMAN" 4 879.4749 38.8 2156 12776 2 879.473413 440.7447 NFX1-type zinc finger-containing protein 1 OS=Homo sapiens OX=9606 GN=ZNFX1 PE=2 SV=2 9.76 2872.8 - 595019 - - - -1.6817 - 1.4 0.189 - 156.3 1 2 0 -0.0015 7 0 0 0 4.06E+07 1.05E+06 - - - 1.5026 0.8566 221125_WJC_METTL3_EV_vs_WT_F01.12777.12777.2 1.47 14-May R.ALNGLLYK.A "sp|Q8N0V3|RBFA_HUMAN,tr|K7EIS1|K7EIS1_HUMAN" 2 890.5226 0.77 2157 12777 2 890.520333 446.2686 "Putative ribosome-binding factor A, mitochondrial OS=Homo sapiens OX=9606 GN=RBFA PE=1 SV=3" 8.63 2872.9 - 467323 - - - -2.4929 - 1.096 0.073 - 60.3 5 2 0 -0.0022 8 0 0 0 1.96E+07 2.54E+07 - - - -0.4563 0.9989 221125_WJC_METTL3_EV_vs_WT_F01.12781.12781.2 0.083 14-Jul R.IFTNLYGR.H "sp|P49821|NDUV1_HUMAN,tr|G3V0I5|G3V0I5_HUMAN,tr|E9PQP1|E9PQP1_HUMAN,tr|E9PPS5|E9PPS5_HUMAN" 4 982.5236 0.97 2159 12781 2 982.522603 492.2691 "NADH dehydrogenase [ubiquinone] flavoprotein 1, mitochondrial OS=Homo sapiens OX=9606 GN=NDUFV1 PE=1 SV=4" 8.75 2873.4 - 1.15E+06 - - - -1.031 - 1.446 0.31 - 164.1 1 2 0 -0.001 8 0 0 0 6.07E+07 6.24E+07 - - - 2.4426 0.9916 221125_WJC_METTL3_EV_vs_WT_F01.12795.12795.2 5.78E-05 16-Oct K.PGTYVIYVR.F "sp|O75369|FLNB_HUMAN,tr|E7EN95|E7EN95_HUMAN,tr|A0A804HK76|A0A804HK76_HUMAN,tr|A0A804HL72|A0A804HL72_HUMAN" 4 1066.5811 0.83 2167 12795 2 1066.582228 534.2978 Filamin-B OS=Homo sapiens OX=9606 GN=FLNB PE=1 SV=2 9 2875 - 333531 - - - 1.0285 - 2.1 0.531 - 479.9 1 1 0 0.0011 9 0 0 0 7.55E+06 9.13E+06 - - - 5.1091 0.9985 221125_WJC_METTL3_EV_vs_WT_F01.12802.12802.2 0.0225 14-Aug K.MMMVLGAK[136.11].W "sp|Q14839|CHD4_HUMAN,tr|A0A2U3TZM0|A0A2U3TZM0_HUMAN,tr|A0A2R8Y685|A0A2R8Y685_HUMAN,tr|A0A2R8Y445|A0A2R8Y445_HUMAN,tr|F5H6N4|F5H6N4_HUMAN,tr|A0A2R8Y5J0|A0A2R8Y5J0_HUMAN,tr|A0A2R8Y425|A0A2R8Y425_HUMAN,tr|A0A2R8YFK9|A0A2R8YFK9_HUMAN,tr|A0A2R8Y8B3|A0A2R8Y8B3_HUMAN,tr|A0A2R8Y8C1|A0A2R8Y8C1_HUMAN,tr|A0A0C4DGG9|A0A0C4DGG9_HUMAN,tr|A0A2R8YFD8|A0A2R8YFD8_HUMAN,tr|A0A2R8Y5Z7|A0A2R8Y5Z7_HUMAN,tr|F5GWX5|F5GWX5_HUMAN,tr|A0A2R8YER1|A0A2R8YER1_HUMAN,tr|A0A2R8Y521|A0A2R8Y521_HUMAN,tr|A0A2R8Y212|A0A2R8Y212_HUMAN" 17 887.4522 0.55 2170 12802 2 887.450922 444.7334 Chromodomain-helicase-DNA-binding protein 4 OS=Homo sapiens OX=9606 GN=CHD4 PE=1 SV=2 8.5 2876 - 733804 - - - -1.4818 - 1.374 0.324 - 209.3 1 2 0 -0.0013 8 0 0 0 1.48E+07 2.67E+07 - - - 2.3919 0.9204 221125_WJC_METTL3_EV_vs_WT_F01.12804.12804.2 2.28 12-Jun K.SLLFNAR.L "sp|Q6KC79|NIPBL_HUMAN,tr|A0A590UJS4|A0A590UJS4_HUMAN" 2 819.4603 1.55 2172 12804 2 819.458028 410.7374 Nipped-B-like protein OS=Homo sapiens OX=9606 GN=NIPBL PE=1 SV=2 9.47 2876.2 - 641630 - - - -2.7567 - 1.204 0.061 - 156.3 1 2 0 -0.0023 7 0 0 0 3.92E+07 2.54E+07 - - - 0.0791 0.9977 221125_WJC_METTL3_EV_vs_WT_F01.12811.12811.2 0.199 12-Aug K.IVVLLQR[166.11].L "sp|Q06323|PSME1_HUMAN,tr|H0YLU2|H0YLU2_HUMAN" 2 849.5675 0.72 2176 12811 2 849.566275 425.791 Proteasome activator complex subunit 1 OS=Homo sapiens OX=9606 GN=PSME1 PE=1 SV=1 9.75 2877.1 - 1.09E+06 - - - -1.4925 - 1.533 0.222 - 241.5 1 2 0 -0.0013 7 0 0 0 2.47E+07 3.43E+07 - - - 2.034 0.9994 221125_WJC_METTL3_EV_vs_WT_F01.12818.12818.2 0.000406 14-Aug K.MMMVLGAK.W "sp|Q14839|CHD4_HUMAN,tr|A0A2U3TZM0|A0A2U3TZM0_HUMAN,tr|A0A2R8Y685|A0A2R8Y685_HUMAN,tr|A0A2R8Y445|A0A2R8Y445_HUMAN,tr|F5H6N4|F5H6N4_HUMAN,tr|A0A2R8Y5J0|A0A2R8Y5J0_HUMAN,tr|A0A2R8Y425|A0A2R8Y425_HUMAN,tr|A0A2R8YFK9|A0A2R8YFK9_HUMAN,tr|A0A2R8Y8B3|A0A2R8Y8B3_HUMAN,tr|A0A2R8Y8C1|A0A2R8Y8C1_HUMAN,tr|A0A0C4DGG9|A0A0C4DGG9_HUMAN,tr|A0A2R8YFD8|A0A2R8YFD8_HUMAN,tr|A0A2R8Y5Z7|A0A2R8Y5Z7_HUMAN,tr|F5GWX5|F5GWX5_HUMAN,tr|A0A2R8YER1|A0A2R8YER1_HUMAN,tr|A0A2R8Y521|A0A2R8Y521_HUMAN,tr|A0A2R8Y212|A0A2R8Y212_HUMAN" 17 879.438 0.42 2179 12818 2 879.436731 440.7263 Chromodomain-helicase-DNA-binding protein 4 OS=Homo sapiens OX=9606 GN=CHD4 PE=1 SV=2 8.5 2878 - 524022 - - - -1.485 - 1.448 0.422 - 174 1 2 0 -0.0013 8 0 0 0 1.50E+07 3.54E+07 - - - 3.2739 0.9804 221125_WJC_METTL3_EV_vs_WT_F01.12826.12826.2 5.5 12-Jul K.LLDIVAR[166.11].S sp|Q12931|TRAP1_HUMAN 1 808.5046 1.92 2182 12826 2 808.503866 405.2596 "Heat shock protein 75 kDa, mitochondrial OS=Homo sapiens OX=9606 GN=TRAP1 PE=1 SV=3" 5.84 2879 - 4.06E+06 - - - -0.919 - 1.369 0.031 - 155.2 1 2 0 -0.0007 7 0 0 0 3.02E+08 1.58E+08 - - - 0.2649 0.9857 221125_WJC_METTL3_EV_vs_WT_F01.12833.12833.2 0.838 14-Aug K.LLIIGPQK.T "sp|P52848|NDST1_HUMAN,tr|E7EVJ3|E7EVJ3_HUMAN" 2 880.5746 0.93 2187 12833 2 880.571303 441.2946 Bifunctional heparan sulfate N-deacetylase\N-sulfotransferase 1 OS=Homo sapiens OX=9606 GN=NDST1 PE=1 SV=1 8.75 2879.8 - 437161 - - - -3.7317 - 1.345 0.258 - 160.5 1 2 0 -0.0033 8 0 0 0 1.44E+07 1.55E+07 - - - 1.8395 0.9997 221125_WJC_METTL3_EV_vs_WT_F01.12834.12834.2 0.000391 14-Sep K.VMMVALGR[166.11].S sp|Q9UKD2|MRT4_HUMAN 1 885.4804 0.57 2188 12834 2 885.479111 443.7475 mRNA turnover protein 4 homolog OS=Homo sapiens OX=9606 GN=MRTO4 PE=1 SV=2 9.72 2879.9 - 701271 - - - -1.4376 - 1.668 0.465 - 299.7 1 2 0 -0.0013 8 0 0 0 1.08E+07 1.90E+07 - - - 4.0181 0.9989 221125_WJC_METTL3_EV_vs_WT_F01.12835.12835.2 0.0544 18-Aug R.AFGSLGPGLR.L "sp|Q96JG8|MAGD4_HUMAN,tr|D6RBW3|D6RBW3_HUMAN,tr|A0A804HHZ9|A0A804HHZ9_HUMAN" 3 973.5345 2 2189 12835 2 973.535216 487.7745 Melanoma-associated antigen D4 OS=Homo sapiens OX=9606 GN=MAGED4 PE=1 SV=3 9.79 2880 - 336011 - - - 0.7201 - 1.512 0.303 - 154 1 2 0 0.0007 10 0 0 0 9.82E+06 4.90E+06 - - - 2.4328 0.9958 221125_WJC_METTL3_EV_vs_WT_F01.12844.12844.2 1.05 12-Jun R.EALGLLR.A "sp|Q8N0Y2|ZN444_HUMAN,tr|K7EK55|K7EK55_HUMAN,tr|K7ELZ3|K7ELZ3_HUMAN,tr|K7EMV5|K7EMV5_HUMAN,tr|K7EJH4|K7EJH4_HUMAN,tr|K7ESL2|K7ESL2_HUMAN,tr|K7EJ91|K7EJ91_HUMAN" 7 770.465 1.28 2193 12844 2 770.464304 386.2398 Zinc finger protein 444 OS=Homo sapiens OX=9606 GN=ZNF444 PE=1 SV=1 6.1 2881.3 - 2.20E+06 - - - -0.9527 - 1.346 0.184 - 155.8 1 2 0 -0.0007 7 0 0 0 8.83E+07 6.93E+07 - - - 1.3413 0.9989 221125_WJC_METTL3_EV_vs_WT_F01.12845.12845.2 0.0337 14-Aug K.LLIIGPQK[136.11].T "sp|P52848|NDST1_HUMAN,tr|E7EVJ3|E7EVJ3_HUMAN" 2 888.5888 0.94 2194 12845 2 888.588015 445.3017 Bifunctional heparan sulfate N-deacetylase\N-sulfotransferase 1 OS=Homo sapiens OX=9606 GN=NDST1 PE=1 SV=1 8.75 2881.4 - 464633 - - - -0.871 - 1.408 0.319 - 194.3 1 2 0 -0.0008 8 0 0 0 1.45E+07 1.55E+07 - - - 2.4289 0.9972 221125_WJC_METTL3_EV_vs_WT_F01.12846.12846.2 0.112 12-Jun K.ELVVLPR.E "sp|Q70IA6|MOB2_HUMAN,tr|A0A087WVS8|A0A087WVS8_HUMAN" 2 824.512 3.55 2195 12846 2 824.511795 413.2633 MOB kinase activator 2 OS=Homo sapiens OX=9606 GN=MOB2 PE=1 SV=1 6.1 2881.5 - 2.04E+06 - - - -0.2353 - 1.258 0.239 - 185.4 1 2 0 -0.0002 7 0 0 0 4.51E+08 1.27E+08 - - - 1.5335 0.9991 221125_WJC_METTL3_EV_vs_WT_F01.12850.12850.2 0.015 12-Jul R.VVFQEFR.Q sp|P35579|MYH9_HUMAN 1 923.4865 0.87 2197 12850 2 923.485929 462.7505 Myosin-9 OS=Homo sapiens OX=9606 GN=MYH9 PE=1 SV=4 5.97 2882 - 604639 - - - -0.6205 - 1.443 0.307 - 202.6 1 2 0 -0.0006 7 0 0 0 1.32E+08 1.51E+08 - - - 2.4703 0.992 221125_WJC_METTL3_EV_vs_WT_F01.12852.12852.2 0.274 14-Jul R.VYLLPDGR[166.11].E sp|O95248|MTMR5_HUMAN 1 941.521 0.67 2199 12852 2 941.522053 471.7678 Myotubularin-related protein 5 OS=Homo sapiens OX=9606 GN=SBF1 PE=1 SV=4 5.81 2882.3 - 143688 - - - 1.1322 - 1.43 0.121 - 130 1 2 0 0.0011 8 0 0 0 6.36E+06 9.43E+06 - - - 1.0131 0.9992 221125_WJC_METTL3_EV_vs_WT_F01.12857.12857.2 0.0138 12-Jul R.VVFQEFR[166.11].Q sp|P35579|MYH9_HUMAN 1 933.4948 0.87 2201 12857 2 933.493987 467.7547 Myosin-9 OS=Homo sapiens OX=9606 GN=MYH9 PE=1 SV=4 5.97 2882.9 - 1.66E+06 - - - -0.8409 - 1.361 0.355 - 235.1 1 2 0 -0.0008 7 0 0 0 1.32E+08 1.51E+08 - - - 2.6394 0.9989 221125_WJC_METTL3_EV_vs_WT_F01.12860.12860.2 0.0742 14-Aug R.ILEVLPGR[166.11].R sp|Q9UI43|MRM2_HUMAN 1 905.5574 1.14 2204 12860 2 905.557962 453.786 "rRNA methyltransferase 2, mitochondrial OS=Homo sapiens OX=9606 GN=MRM2 PE=1 SV=1" 6 2883.2 - 289592 - - - 0.6515 - 1.586 0.268 - 170.8 1 2 0 0.0006 8 0 0 0 2.07E+07 1.83E+07 - - - 2.4113 0.9967 221125_WJC_METTL3_EV_vs_WT_F01.12861.12861.2 0.0147 14-Jun R.FLAYMEDR[166.11].R "sp|Q9HCK8|CHD8_HUMAN,tr|H0YJG4|H0YJG4_HUMAN" 2 1053.4829 0.64 2205 12861 2 1053.482703 527.7487 Chromodomain-helicase-DNA-binding protein 8 OS=Homo sapiens OX=9606 GN=CHD8 PE=1 SV=5 4.37 2883.3 - 169337 - - - -0.1747 - 1.18 0.251 - 141.9 1 2 0 -0.0002 8 0 0 0 3.10E+06 4.87E+06 - - - 1.394 0.9991 221125_WJC_METTL3_EV_vs_WT_F01.12873.12873.2 0.123 18-Nov R.LLAEPVPGIK.A "sp|P61088|UBE2N_HUMAN,sp|Q5JXB2|UE2NL_HUMAN,tr|F8VZ29|F8VZ29_HUMAN,tr|F8VSD4|F8VSD4_HUMAN,tr|F8VV71|F8VV71_HUMAN" 5 1035.6328 0.89 2213 12873 2 1035.632577 518.8237 Ubiquitin-conjugating enzyme E2 N OS=Homo sapiens OX=9606 GN=UBE2N PE=1 SV=1 6 2884.8 - 816748 - - - -0.2462 - 1.797 0.239 - 340.3 1 2 0 -0.0003 10 0 0 0 9.38E+07 1.06E+08 - - - 2.4422 0.9989 221125_WJC_METTL3_EV_vs_WT_F01.12874.12874.2 0.455 14-Sep R.LGALALPR[166.11].G "sp|Q6SPF0|SAMD1_HUMAN,tr|E9PIW9|E9PIW9_HUMAN" 2 819.5206 2.37 2214 12874 2 819.520583 410.7676 Sterile alpha motif domain-containing protein 1 OS=Homo sapiens OX=9606 GN=SAMD1 PE=1 SV=1 9.75 2884.9 - 683805 - - - -0.0122 - 1.82 0.192 - 293.1 1 2 0 0 8 0 0 0 2.74E+08 1.16E+08 - - - 2.2652 0.9585 221125_WJC_METTL3_EV_vs_WT_F01.12881.12881.2 0.147 12-Apr R.YYTVFDR.D "sp|P07339|CATD_HUMAN,tr|A0A1B0GW44|A0A1B0GW44_HUMAN,tr|A0A1B0GVD5|A0A1B0GVD5_HUMAN,tr|A0A1B0GV23|A0A1B0GV23_HUMAN,tr|C9JH19|C9JH19_HUMAN,tr|H7C469|H7C469_HUMAN,tr|A0A1B0GWE8|A0A1B0GWE8_HUMAN,tr|A0A1B0GVP3|A0A1B0GVP3_HUMAN,tr|F8W787|F8W787_HUMAN" 9 962.4498 0.38 2218 12881 2 962.447356 482.2322 Cathepsin D OS=Homo sapiens OX=9606 GN=CTSD PE=1 SV=1 5.83 2885.9 - 290463 - - - -2.5207 - 1.024 0.194 - 47.1 2 2 0 -0.0024 7 0 0 0 9.92E+06 2.59E+07 - - - 0.4138 0.9998 221125_WJC_METTL3_EV_vs_WT_F01.12890.12890.2 0.0016 16-Nov K.TLLDIDNTR.M sp|P35527|K1C9_HUMAN 1 1059.556 231.29 2225 12890 2 1059.555323 530.7853 "Keratin, type I cytoskeletal 9 OS=Homo sapiens OX=9606 GN=KRT9 PE=1 SV=3" 4.21 2887 - 949982 - - - -0.6748 - 1.998 0.45 - 391.8 1 2 0 -0.0007 9 0 0 0 2.84E+07 1.23E+05 - - - 4.3669 0.9991 221125_WJC_METTL3_EV_vs_WT_F01.12891.12891.2 0.644 14-Aug K.LVALNLDR.L "sp|Q9Y3D3|RT16_HUMAN,tr|A6ND22|A6ND22_HUMAN" 2 912.5393 2.18 2226 12891 2 912.538788 457.2769 "28S ribosomal protein S16, mitochondrial OS=Homo sapiens OX=9606 GN=MRPS16 PE=1 SV=1" 5.84 2887.1 - 901423 - - - -0.5238 - 1.706 0.243 - 209 1 2 0 -0.0005 8 0 0 0 6.33E+07 2.90E+07 - - - 2.4466 0.8306 221125_WJC_METTL3_EV_vs_WT_F01.12893.12893.2 8.94 12-May R.FPPYYMR.R "sp|P67809|YBOX1_HUMAN,tr|H0Y449|H0Y449_HUMAN,tr|C9J5V9|C9J5V9_HUMAN" 3 972.4528 1.36 2228 12893 2 972.453362 487.2337 Y-box-binding protein 1 OS=Homo sapiens OX=9606 GN=YBX1 PE=1 SV=3 8.59 2887.4 - 265962 - - - 0.6201 - 0.878 0.024 - 87.2 1 2 0 0.0006 7 0 0 0 1.93E+07 1.42E+07 - - - -1.1942 0.9951 221125_WJC_METTL3_EV_vs_WT_F01.12897.12897.2 0.687 16-Aug R.ILVGTNLVR.L sp|Q96QK1|VPS35_HUMAN 1 983.6128 0.72 2230 12897 2 983.612258 492.8137 Vacuolar protein sorting-associated protein 35 OS=Homo sapiens OX=9606 GN=VPS35 PE=1 SV=2 9.75 2887.9 - 664755 - - - -0.5154 - 1.442 0.14 - 170.8 1 2 0 -0.0005 9 0 0 0 3.73E+07 5.17E+07 - - - 1.1338 0.9992 221125_WJC_METTL3_EV_vs_WT_F01.12898.12898.2 0.0162 18-Oct R.LLAEPVPGIK[136.11].A "sp|P61088|UBE2N_HUMAN,sp|Q5JXB2|UE2NL_HUMAN,tr|F8VZ29|F8VZ29_HUMAN,tr|F8VSD4|F8VSD4_HUMAN,tr|F8VV71|F8VV71_HUMAN" 5 1043.647 0.89 2231 12898 2 1043.646286 522.8308 Ubiquitin-conjugating enzyme E2 N OS=Homo sapiens OX=9606 GN=UBE2N PE=1 SV=1 6 2887.9 - 2.31E+06 - - - -0.7148 - 2.087 0.203 - 297.4 1 2 0 -0.0007 10 0 0 0 9.38E+07 1.06E+08 - - - 2.5938 0.9561 221125_WJC_METTL3_EV_vs_WT_F01.12906.12906.2 3.25 16-Jun R.ILVGTNLVR[166.11].L sp|Q96QK1|VPS35_HUMAN 1 993.621 0.72 2236 12906 2 993.619679 497.8178 Vacuolar protein sorting-associated protein 35 OS=Homo sapiens OX=9606 GN=VPS35 PE=1 SV=2 9.75 2888.9 - 1.53E+06 - - - -1.3647 - 0.994 0.115 - 64.1 1 2 0 -0.0014 9 0 0 0 3.73E+07 5.17E+07 - - - -0.1274 0.9977 221125_WJC_METTL3_EV_vs_WT_F01.12920.12920.2 0.0258 16-May R.MPVGSPLLR[166.11].D "sp|Q9NVS2|RT18A_HUMAN,tr|Q5QPA5|Q5QPA5_HUMAN" 2 978.556 0.94 2244 12920 2 978.554358 490.2853 "39S ribosomal protein S18a, mitochondrial OS=Homo sapiens OX=9606 GN=MRPS18A PE=1 SV=1" 9.5 2890.6 - 351369 - - - -1.6698 - 1.224 0.34 - 69 1 2 0 -0.0016 9 0 0 0 3.62E+07 3.85E+07 - - - 2.1365 0.9988 221125_WJC_METTL3_EV_vs_WT_F01.12921.12921.2 0.0111 14-Jul R.ILEVLPGR.R sp|Q9UI43|MRM2_HUMAN 1 895.5491 1.13 2245 12921 2 895.549965 448.7818 "rRNA methyltransferase 2, mitochondrial OS=Homo sapiens OX=9606 GN=MRM2 PE=1 SV=1" 6 2890.7 - 613809 - - - 0.9637 - 1.447 0.307 - 124.7 1 2 0 0.0009 8 0 0 0 2.07E+07 1.83E+07 - - - 2.4226 0.9994 221125_WJC_METTL3_EV_vs_WT_F01.12927.12927.2 0.00394 12-Aug R.VVFQEFR.Q sp|P35579|MYH9_HUMAN 1 923.4865 0.87 2249 12927 2 923.485773 462.7505 Myosin-9 OS=Homo sapiens OX=9606 GN=MYH9 PE=1 SV=4 5.97 2891.5 - 3.56E+06 - - - -0.7894 - 1.485 0.37 - 242.6 1 2 0 -0.0007 7 0 0 0 1.32E+08 1.51E+08 - - - 3.0265 0.9698 221125_WJC_METTL3_EV_vs_WT_F01.12931.12931.2 0.76 16-Jun R.IIEETLALK.F "sp|O15144|ARPC2_HUMAN,tr|C9JTV5|C9JTV5_HUMAN,tr|G5E9J0|G5E9J0_HUMAN,tr|G5E9S7|G5E9S7_HUMAN" 4 1028.6118 0.55 2251 12931 2 1028.614107 515.3132 Actin-related protein 2\3 complex subunit 2 OS=Homo sapiens OX=9606 GN=ARPC2 PE=1 SV=1 4.53 2892 - 131344 - - - 2.2798 - 1.081 0.174 - 63.4 1 2 0 0.0023 9 0 0 0 3.28E+07 5.93E+07 - - - 0.5508 0.9984 221125_WJC_METTL3_EV_vs_WT_F01.12952.12952.2 0.0398 14-Sep R.IGVAILQR[166.11].S "sp|Q68CQ4|UTP25_HUMAN,tr|H7C2R4|H7C2R4_HUMAN" 2 878.5577 0.49 2260 12952 2 878.556579 440.2861 U3 small nucleolar RNA-associated protein 25 homolog OS=Homo sapiens OX=9606 GN=UTP25 PE=1 SV=2 9.75 2894.8 - 478224 - - - -1.2839 - 1.668 0.227 - 223.6 1 2 0 -0.0011 8 0 0 0 6.80E+06 1.39E+07 - - - 2.2603 0.9715 221125_WJC_METTL3_EV_vs_WT_F01.12957.12957.2 1.24 12-May K.ELVVLPR[166.11].E "sp|Q70IA6|MOB2_HUMAN,tr|A0A087WVS8|A0A087WVS8_HUMAN" 2 834.5203 3.61 2261 12957 2 834.520376 418.2674 MOB kinase activator 2 OS=Homo sapiens OX=9606 GN=MOB2 PE=1 SV=1 6.1 2895.6 - 1.48E+06 - - - 0.1402 - 1.126 0.07 - 105.1 1 2 0 0.0001 7 0 0 0 4.49E+08 1.24E+08 - - - -0.066 0.8328 221125_WJC_METTL3_EV_vs_WT_F01.12958.12958.2 0.336 12-Jun K.ALFTYPK.G "sp|Q96DE5|APC16_HUMAN,tr|A0A087WUN5|A0A087WUN5_HUMAN" 2 838.4589 1.86 2262 12958 2 838.454171 420.2367 Anaphase-promoting complex subunit 16 OS=Homo sapiens OX=9606 GN=ANAPC16 PE=1 SV=1 8.63 2895.7 - 625030 - - - -5.6282 - 1.153 0.191 - 114.8 1 2 0 -0.0047 7 0 0 0 4.24E+07 2.28E+07 - - - 0.9013 0.9812 221125_WJC_METTL3_EV_vs_WT_F01.12961.12961.2 0.0558 12-Aug K.PSVYFIK[136.11].F "sp|Q99865|SPI2A_HUMAN,sp|Q56A73|SPIN4_HUMAN,sp|Q9BPZ2|SPI2B_HUMAN,sp|Q5JUX0|SPIN3_HUMAN,sp|Q9Y657|SPIN1_HUMAN,tr|A0A087X074|A0A087X074_HUMAN,tr|Q5JZB8|Q5JZB8_HUMAN,tr|Q5JZB7|Q5JZB7_HUMAN,tr|A0A1W2PR54|A0A1W2PR54_HUMAN" 9 860.4887 1.92 2263 12961 2 860.487468 431.2516 Spindlin-2A OS=Homo sapiens OX=9606 GN=SPIN2A PE=1 SV=3 9.01 2896.1 - 4.57E+06 - - - -1.4794 - 1.925 0.395 - 177.3 1 1 0 -0.0013 7 0 0 0 3.36E+08 1.75E+08 - - - 4.0332 0.9929 221125_WJC_METTL3_EV_vs_WT_F01.12962.12962.2 0.724 12-May K.VLLDQLR[166.11].F "sp|Q9HDC9|APMAP_HUMAN,tr|H0Y512|H0Y512_HUMAN" 2 865.5261 0.97 2264 12962 2 865.525156 433.7703 Adipocyte plasma membrane-associated protein OS=Homo sapiens OX=9606 GN=APMAP PE=1 SV=2 5.81 2896.2 - 2.29E+06 - - - -1.0583 - 1.102 0.223 - 86.4 1 2 0 -0.0009 7 0 0 0 1.85E+08 1.92E+08 - - - 0.9955 0.9962 221125_WJC_METTL3_EV_vs_WT_F01.12979.12979.2 0.471 12-Jul K.VLLDQLR.F "sp|Q9HDC9|APMAP_HUMAN,tr|H0Y512|H0Y512_HUMAN" 2 855.5178 0.94 2274 12979 2 855.516765 428.7662 Adipocyte plasma membrane-associated protein OS=Homo sapiens OX=9606 GN=APMAP PE=1 SV=2 5.81 2898.2 - 4.74E+06 - - - -1.2121 - 1.485 0.165 - 216.7 1 2 0 -0.001 7 0 0 0 1.85E+08 1.98E+08 - - - 1.5123 0.9999 221125_WJC_METTL3_EV_vs_WT_F01.12980.12980.2 0.000281 12-Sep K.C[160.03]FLTAMR.E "sp|Q8WVD3|RN138_HUMAN,tr|J3QKM8|J3QKM8_HUMAN,tr|J3KSI2|J3KSI2_HUMAN" 3 897.4201 1.32 2275 12980 2 897.419436 449.7173 E3 ubiquitin-protein ligase RNF138 OS=Homo sapiens OX=9606 GN=RNF138 PE=1 SV=1 8.25 2898.3 - 1.47E+06 - - - -0.7165 - 1.905 0.491 - 420.3 1 2 0 -0.0006 7 0 0 0 6.53E+07 4.97E+07 - - - 4.7094 0.9703 221125_WJC_METTL3_EV_vs_WT_F01.12992.12992.2 0.0199 12-Jul P.FPAALLR.V "sp|Q9H0D2|ZN541_HUMAN,sp|Q9UJV9|DDX41_HUMAN,tr|H7BXG6|H7BXG6_HUMAN,tr|M0R167|M0R167_HUMAN,tr|A0A499FJW5|A0A499FJW5_HUMAN,tr|A0A075B6F0|A0A075B6F0_HUMAN,tr|H0Y8L8|H0Y8L8_HUMAN" 7 786.4752 0.49 2282 12992 2 786.474636 394.2449 Zinc finger protein 541 OS=Homo sapiens OX=9606 GN=ZNF541 PE=1 SV=3 9.75 2899.8 - 3.09E+06 - - - -0.7286 - 1.661 0.33 - 220.8 1 1 0 -0.0006 7 0 0 0 2.32E+08 4.72E+08 - - - 3.086 0.9734 221125_WJC_METTL3_EV_vs_WT_F01.12997.12997.2 0.048 14-Jul K.LLQPLVPR[166.11].Y sp|Q8N8A6|DDX51_HUMAN 1 944.6047 1.07 2285 12997 2 944.60263 473.3096 ATP-dependent RNA helicase DDX51 OS=Homo sapiens OX=9606 GN=DDX51 PE=1 SV=3 9.75 2900.4 - 183646 - - - -2.1459 - 1.309 0.093 - 130.5 1 2 0 -0.002 8 0 0 0 5.35E+07 5.00E+07 - - - 0.5393 0.9995 221125_WJC_METTL3_EV_vs_WT_F01.13000.13000.2 0.0929 14-Sep K.LLQLVEDR[166.11].G "sp|P17844|DDX5_HUMAN,tr|J3KTA4|J3KTA4_HUMAN,tr|A0A0G2JLI4|A0A0G2JLI4_HUMAN" 3 994.5687 1.27 2286 13000 2 994.56802 498.2916 Probable ATP-dependent RNA helicase DDX5 OS=Homo sapiens OX=9606 GN=DDX5 PE=1 SV=1 4.37 2900.8 - 888926 - - - -0.6485 - 2.048 0.257 - 333.3 1 2 0 -0.0006 8 0 0 0 1.81E+08 1.43E+08 - - - 3.101 0.9993 221125_WJC_METTL3_EV_vs_WT_F01.13004.13004.2 0.164 16-Oct K.VVLLTEVDK.L sp|P40938|RFC3_HUMAN 1 1014.5961 1 2290 13004 2 1014.598004 508.3053 Replication factor C subunit 3 OS=Homo sapiens OX=9606 GN=RFC3 PE=1 SV=2 4.37 2901.3 - 263989 - - - 1.8648 - 2.007 0.325 - 326.2 1 2 0 0.0019 9 0 0 0 2.16E+07 2.16E+07 - - - 3.4563 0.9987 221125_WJC_METTL3_EV_vs_WT_F01.13007.13007.2 0.591 14-Sep K.IADFGLAR.L "sp|P07947|YES_HUMAN,sp|P51451|BLK_HUMAN,sp|Q9UPZ9|CILK1_HUMAN,sp|Q00537|CDK17_HUMAN,sp|P24941|CDK2_HUMAN,sp|P50750|CDK9_HUMAN,sp|Q07002|CDK18_HUMAN,sp|P22455|FGFR4_HUMAN,sp|Q00526|CDK3_HUMAN,sp|Q9NYV4|CDK12_HUMAN,sp|Q00534|CDK6_HUMAN,sp|P11802|CDK4_HUMAN,sp|Q00536|CDK16_HUMAN,sp|P09769|FGR_HUMAN,sp|P06239|LCK_HUMAN,sp|P20794|MAK_HUMAN,sp|P07948|LYN_HUMAN,sp|P06493|CDK1_HUMAN,sp|Q14004|CDK13_HUMAN,sp|P11362|FGFR1_HUMAN,sp|O94921|CDK14_HUMAN,sp|P08631|HCK_HUMAN,sp|Q00535|CDK5_HUMAN,sp|P06241|FYN_HUMAN,sp|P21802|FGFR2_HUMAN,sp|Q96Q40|CDK15_HUMAN,sp|P22607|FGFR3_HUMAN,sp|Q8IZL9|CDK20_HUMAN,tr|D2CGD1|D2CGD1_HUMAN,tr|A0A3B3ISD1|A0A3B3ISD1_HUMAN,tr|A0A0S2Z3T4|A0A0S2Z3T4_HUMAN,tr|A0A6Q8PG01|A0A6Q8PG01_HUMAN,tr|J3QSD7|J3QSD7_HUMAN,tr|Q573B4|Q573B4_HUMAN,tr|E9PJX5|E9PJX5_HUMAN,tr|E5RIU6|E5RIU6_HUMAN,tr|H0YE20|H0YE20_HUMAN,tr|E7EVR7|E7EVR7_HUMAN,tr|H0Y3C5|H0Y3C5_HUMAN,tr|A0A2R8Y4Z0|A0A2R8Y4Z0_HUMAN,tr|G3V5T9|G3V5T9_HUMAN,tr|F8VWX7|F8VWX7_HUMAN,tr|A0A2R8YD28|A0A2R8YD28_HUMAN,tr|F5H6Z0|F5H6Z0_HUMAN,tr|J3KPD6|J3KPD6_HUMAN,tr|F8VXD2|F8VXD2_HUMAN,tr|A0A2R8YEB7|A0A2R8YEB7_HUMAN,tr|S4R381|S4R381_HUMAN,tr|Q9BVE2|Q9BVE2_HUMAN,tr|A0A804HIF1|A0A804HIF1_HUMAN,tr|E5RGN0|E5RGN0_HUMAN,tr|A0A2R8YF61|A0A2R8YF61_HUMAN,tr|A0A087X209|A0A087X209_HUMAN,tr|E7EUK8|E7EUK8_HUMAN,tr|E7ESI2|E7ESI2_HUMAN,tr|K7EJ83|K7EJ83_HUMAN,tr|A0A1W2PQT9|A0A1W2PQT9_HUMAN,tr|H7BXU9|H7BXU9_HUMAN,tr|A0A024QZP7|A0A024QZP7_HUMAN,tr|Q8IXN4|Q8IXN4_HUMAN,tr|A0A087WZZ9|A0A087WZZ9_HUMAN,tr|A0A7I2PIU1|A0A7I2PIU1_HUMAN,tr|H0Y9P2|H0Y9P2_HUMAN,tr|A0A7I2RW32|A0A7I2RW32_HUMAN,tr|A0A0A0MR25|A0A0A0MR25_HUMAN,tr|F8VZZ0|F8VZZ0_HUMAN,tr|J3QRU1|J3QRU1_HUMAN,tr|F8VTV8|F8VTV8_HUMAN,tr|H7C265|H7C265_HUMAN,tr|E7EU09|E7EU09_HUMAN,tr|A0A2R8Y7W5|A0A2R8Y7W5_HUMAN,tr|H0YAZ9|H0YAZ9_HUMAN,tr|F8VYH9|F8VYH9_HUMAN,tr|A0A2R8Y644|A0A2R8Y644_HUMAN,tr|A0A804HI76|A0A804HI76_HUMAN,tr|F8W9L4|F8W9L4_HUMAN,tr|A0A5S6RJB7|A0A5S6RJB7_HUMAN,tr|F8VZ51|F8VZ51_HUMAN,tr|A0A087WZU2|A0A087WZU2_HUMAN,tr|A0A6Q8PH30|A0A6Q8PH30_HUMAN,tr|J3KPQ0|J3KPQ0_HUMAN" 81 861.4709 0.81 2291 13007 2 861.469396 431.7427 Tyrosine-protein kinase Yes OS=Homo sapiens OX=9606 GN=YES1 PE=1 SV=3 5.84 2901.7 - 6.10E+06 - - - -1.6901 - 1.751 0.261 - 266.7 1 2 0 -0.0015 8 0 0 0 3.56E+08 4.41E+08 - - - 2.6578 0.9955 221125_WJC_METTL3_EV_vs_WT_F01.13013.13013.2 0.215 14-Aug K.LLQLVEDR.G "sp|P17844|DDX5_HUMAN,tr|J3KTA4|J3KTA4_HUMAN,tr|A0A0G2JLI4|A0A0G2JLI4_HUMAN" 3 984.5604 0.45 2295 13013 2 984.557856 493.2875 Probable ATP-dependent RNA helicase DDX5 OS=Homo sapiens OX=9606 GN=DDX5 PE=1 SV=1 4.37 2902.4 - 2.75E+06 - - - -2.5788 - 1.646 0.211 - 169.4 1 2 0 -0.0025 8 0 0 0 2.08E+08 4.62E+08 - - - 2.1016 0.9181 221125_WJC_METTL3_EV_vs_WT_F01.13015.13015.2 0.313 14-Aug R.ALVIVMGK[136.11].E "tr|G5E9Q6|G5E9Q6_HUMAN,tr|C9J0J7|C9J0J7_HUMAN" 2 837.5237 0.84 2297 13015 2 837.520566 419.7691 Profilin OS=Homo sapiens OX=9606 GN=PFN2 PE=1 SV=1 8.8 2902.6 - 1.79E+06 - - - -3.7969 - 1.563 0.023 - 199.6 1 2 0 -0.0032 8 0 0 0 4.65E+07 5.56E+07 - - - 0.5568 0.9996 221125_WJC_METTL3_EV_vs_WT_F01.13018.13018.2 0.00628 22-Aug R.LLSASPVDAAIR[166.11].V "sp|Q9NRG9|AAAS_HUMAN,tr|H3BU82|H3BU82_HUMAN,tr|F8VZ44|F8VZ44_HUMAN" 3 1221.6957 1.63 2300 13018 2 1221.693917 611.8551 Aladin OS=Homo sapiens OX=9606 GN=AAAS PE=1 SV=1 5.84 2903 - 245560 - - - -1.4242 - 1.733 0.429 - 197.6 1 2 0 -0.0017 12 0 0 0 1.57E+07 9.67E+06 - - - 3.6558 0.9996 221125_WJC_METTL3_EV_vs_WT_F01.13019.13019.2 5.10E-05 24-Oct R.TTPSYVAFTDTER[166.11].L "sp|P48741|HSP77_HUMAN,sp|P54652|HSP72_HUMAN,sp|P0DMV8|HS71A_HUMAN,sp|P34931|HS71L_HUMAN,sp|P11142|HSP7C_HUMAN,sp|P0DMV9|HS71B_HUMAN,sp|P17066|HSP76_HUMAN,tr|E9PQQ4|E9PQQ4_HUMAN,tr|E9PNE6|E9PNE6_HUMAN,tr|E9PKE3|E9PKE3_HUMAN,tr|E9PLF4|E9PLF4_HUMAN,tr|Q53FA3|Q53FA3_HUMAN,tr|E9PI65|E9PI65_HUMAN,tr|E9PK54|E9PK54_HUMAN,tr|E9PN25|E9PN25_HUMAN,tr|E9PPY6|E9PPY6_HUMAN,tr|E9PQK7|E9PQK7_HUMAN,tr|A0A0G2JIW1|A0A0G2JIW1_HUMAN" 18 1496.7023 0.14 2301 13019 2 1496.704593 749.3584 Putative heat shock 70 kDa protein 7 OS=Homo sapiens OX=9606 GN=HSPA7 PE=5 SV=2 4.37 2903.1 - 228909 - - - 1.5594 - 1.802 0.476 - 124.9 1 2 0 0.0023 13 0 0 0 4.49E+06 3.25E+07 - - - 4.0674 0.9892 221125_WJC_METTL3_EV_vs_WT_F01.13023.13023.2 0.00968 20-Jul K.QAGVFEPTIVK[136.11].V "sp|P17987|TCPA_HUMAN,tr|F5H282|F5H282_HUMAN,tr|E7EQR6|E7EQR6_HUMAN" 3 1195.6692 0.43 2303 13023 2 1195.671101 598.8419 T-complex protein 1 subunit alpha OS=Homo sapiens OX=9606 GN=TCP1 PE=1 SV=1 6 2903.6 - 143464 - - - 1.5698 - 1.272 0.172 - 138.8 1 2 0 0.0019 11 0 0 0 1.84E+06 4.28E+06 - - - 0.9617 0.9722 221125_WJC_METTL3_EV_vs_WT_F01.13035.13035.2 0.0714 14-Jul K.LLQPLVPR.Y sp|Q8N8A6|DDX51_HUMAN 1 934.5964 1.07 2309 13035 2 934.594607 468.3055 ATP-dependent RNA helicase DDX51 OS=Homo sapiens OX=9606 GN=DDX51 PE=1 SV=3 9.75 2905.2 - 589137 - - - -1.9046 - 1.432 0.055 - 153.6 2 2 0 -0.0018 8 0 0 0 5.35E+07 4.99E+07 - - - 0.3951 0.9993 221125_WJC_METTL3_EV_vs_WT_F01.13037.13037.2 5.11E-06 24-Sep R.TTPSYVAFTDTER.L "sp|P48741|HSP77_HUMAN,sp|P54652|HSP72_HUMAN,sp|P0DMV8|HS71A_HUMAN,sp|P34931|HS71L_HUMAN,sp|P11142|HSP7C_HUMAN,sp|P0DMV9|HS71B_HUMAN,sp|P17066|HSP76_HUMAN,tr|E9PQQ4|E9PQQ4_HUMAN,tr|E9PNE6|E9PNE6_HUMAN,tr|E9PKE3|E9PKE3_HUMAN,tr|E9PLF4|E9PLF4_HUMAN,tr|Q53FA3|Q53FA3_HUMAN,tr|E9PI65|E9PI65_HUMAN,tr|E9PK54|E9PK54_HUMAN,tr|E9PN25|E9PN25_HUMAN,tr|E9PPY6|E9PPY6_HUMAN,tr|E9PQK7|E9PQK7_HUMAN,tr|A0A0G2JIW1|A0A0G2JIW1_HUMAN" 18 1486.694 0.14 2310 13037 2 1486.68924 744.3543 Putative heat shock 70 kDa protein 7 OS=Homo sapiens OX=9606 GN=HSPA7 PE=5 SV=2 4.37 2905.4 - 116306 - - - -3.1943 - 1.842 0.553 - 212.6 1 2 0 -0.0047 13 0 0 0 4.49E+06 3.24E+07 - - - 4.6917 0.9997 221125_WJC_METTL3_EV_vs_WT_F01.13040.13040.2 0.000479 22-Oct R.LLSASPVDAAIR.V "sp|Q9NRG9|AAAS_HUMAN,tr|H3BU82|H3BU82_HUMAN,tr|F8VZ44|F8VZ44_HUMAN" 3 1211.6874 1.63 2312 13040 2 1211.686344 606.851 Aladin OS=Homo sapiens OX=9606 GN=AAAS PE=1 SV=1 5.84 2905.8 - 688599 - - - -0.8608 - 1.816 0.412 - 206.3 1 2 0 -0.001 12 0 0 0 1.57E+07 9.67E+06 - - - 3.6536 0.9797 221125_WJC_METTL3_EV_vs_WT_F01.13044.13044.2 1.33 12-May K.IMMEFER.Q "sp|O43633|CHM2A_HUMAN,tr|M0R1L7|M0R1L7_HUMAN,tr|M0R1T5|M0R1T5_HUMAN" 3 954.4303 0.84 2314 13044 2 954.429134 478.2224 Charged multivesicular body protein 2a OS=Homo sapiens OX=9606 GN=CHMP2A PE=1 SV=1 4.53 2906.3 - 472880 - - - -1.2311 - 1.003 0.174 - 77.5 1 2 0 -0.0012 7 0 0 0 1.50E+07 1.79E+07 - - - 0.3353 0.8823 221125_WJC_METTL3_EV_vs_WT_F01.13055.13055.2 0.219 18-Sep L.FLGVAYGATR[166.11].Y sp|P56385|ATP5I_HUMAN 1 1063.569 1.82 2321 13055 2 1063.569539 532.7918 "ATP synthase subunit e, mitochondrial OS=Homo sapiens OX=9606 GN=ATP5ME PE=1 SV=2" 8.75 2907.7 - 373688 - - - 0.5068 - 1.77 0.155 - 243.9 1 1 0 0.0005 10 0 0 0 1.63E+07 8.96E+06 - - - 1.7794 0.9995 221125_WJC_METTL3_EV_vs_WT_F01.13069.13069.2 0.0153 14-Aug R.ALVIVMGK.E "tr|G5E9Q6|G5E9Q6_HUMAN,tr|C9J0J7|C9J0J7_HUMAN" 2 829.5095 0.84 2329 13069 2 829.509147 415.762 Profilin OS=Homo sapiens OX=9606 GN=PFN2 PE=1 SV=1 8.8 2909.4 - 1.24E+06 - - - -0.481 - 1.645 0.341 - 268.6 1 2 0 -0.0004 8 0 0 0 4.65E+07 5.56E+07 - - - 3.0607 0.9748 221125_WJC_METTL3_EV_vs_WT_F01.13070.13070.2 8.5 18-Apr R.IISDISVPC[160.03]K.V "sp|A6H8Z2|F221B_HUMAN,tr|F8W8N9|F8W8N9_HUMAN" 2 1130.6005 1.31 2330 13070 2 1130.601085 566.3075 Protein FAM221B OS=Homo sapiens OX=9606 GN=FAM221B PE=1 SV=2 5.83 2909.6 - 115736 - - - 0.4767 - 0.901 0.177 - 30.6 1 2 0 0.0005 10 0 0 0 8.63E+06 6.61E+06 - - - 0.0572 0.9997 221125_WJC_METTL3_EV_vs_WT_F01.13073.13073.2 0.00142 28-Jun K.NQVAMNPTNTVFDAK[136.11].R "sp|P11142|HSP7C_HUMAN,tr|E9PQQ4|E9PQQ4_HUMAN,tr|E9PNE6|E9PNE6_HUMAN,tr|E9PKE3|E9PKE3_HUMAN,tr|E9PLF4|E9PLF4_HUMAN,tr|E9PK54|E9PK54_HUMAN,tr|E9PN25|E9PN25_HUMAN,tr|E9PPY6|E9PPY6_HUMAN,tr|E9PQK7|E9PQK7_HUMAN" 9 1656.8021 0.05 2331 13073 2 1656.801462 829.4083 Heat shock cognate 71 kDa protein OS=Homo sapiens OX=9606 GN=HSPA8 PE=1 SV=1 5.84 2910 - 140789 - - - -0.3887 - 1.377 0.505 - 92 1 2 0 -0.0006 15 0 0 0 2.99E+05 6.06E+06 - - - 3.5572 0.995 221125_WJC_METTL3_EV_vs_WT_F01.13075.13075.2 2.85 16-Aug K.LPPLPAVER.V "sp|O95793|STAU1_HUMAN,tr|Q5JW30|Q5JW30_HUMAN,tr|Q5JW28|Q5JW28_HUMAN" 3 990.5862 1.78 2333 13075 2 990.585997 496.3004 Double-stranded RNA-binding protein Staufen homolog 1 OS=Homo sapiens OX=9606 GN=STAU1 PE=1 SV=2 6 2910.2 - 2.55E+06 - - - -0.2211 - 1.766 0.056 - 233.4 1 2 0 -0.0002 9 0 0 0 2.59E+08 1.46E+08 - - - 1.0999 0.9963 221125_WJC_METTL3_EV_vs_WT_F01.13082.13082.2 0.212 14-Sep K.LAVEAVLR.L "sp|P78371|TCPB_HUMAN,tr|F8VQ14|F8VQ14_HUMAN,tr|F5GWF6|F5GWF6_HUMAN" 3 869.5335 0.51 2337 13082 2 869.534133 435.774 T-complex protein 1 subunit beta OS=Homo sapiens OX=9606 GN=CCT2 PE=1 SV=4 6 2911 - 3.83E+06 - - - 0.7832 - 1.616 0.131 - 297.6 1 2 0 0.0007 8 0 0 0 9.39E+08 1.83E+09 - - - 1.4559 0.9975 221125_WJC_METTL3_EV_vs_WT_F01.13083.13083.2 1.25 12-Jul K.EAVLLLK[136.11].K "sp|P36578|RL4_HUMAN,tr|H3BTP7|H3BTP7_HUMAN,tr|H3BM89|H3BM89_HUMAN" 3 792.52 1.02 2338 13083 2 792.520082 397.2673 60S ribosomal protein L4 OS=Homo sapiens OX=9606 GN=RPL4 PE=1 SV=5 6.1 2911.1 - 1.96E+06 - - - 0.0517 - 1.415 0.198 - 236.8 1 2 0 0 7 0 0 0 2.01E+08 1.97E+08 - - - 1.6033 0.9873 221125_WJC_METTL3_EV_vs_WT_F01.13084.13084.2 3.91 12-Jun K.EAVLLLK.K "sp|P36578|RL4_HUMAN,tr|H3BTP7|H3BTP7_HUMAN,tr|H3BM89|H3BM89_HUMAN" 3 784.5058 1.02 2339 13084 2 784.505895 393.2602 60S ribosomal protein L4 OS=Homo sapiens OX=9606 GN=RPL4 PE=1 SV=5 6.1 2911.2 - 1.63E+06 - - - 0.0688 - 1.339 0.067 - 153.2 1 2 0 0.0001 7 0 0 0 2.03E+08 1.98E+08 - - - 0.4608 0.9629 221125_WJC_METTL3_EV_vs_WT_F01.13090.13090.2 0.0391 12-Jul P.LVLYIDR[166.11].F "sp|Q9NQV6|PRD10_HUMAN,sp|Q9UBB9|TFP11_HUMAN,tr|E9PLV1|E9PLV1_HUMAN" 3 900.5308 0.88 2343 13090 2 900.530712 451.2727 PR domain zinc finger protein 10 OS=Homo sapiens OX=9606 GN=PRDM10 PE=1 SV=3 5.84 2911.8 - 645196 - - - -0.1233 - 1.597 0.304 - 192 1 1 0 -0.0001 7 0 0 0 1.67E+07 1.91E+07 - - - 2.7696 0.9883 221125_WJC_METTL3_EV_vs_WT_F01.13094.13094.2 0.729 12-Jun R.YLLLNPK.E "sp|O14776|TCRG1_HUMAN,tr|A0A7P0T8N8|A0A7P0T8N8_HUMAN,tr|G3V220|G3V220_HUMAN" 3 859.5167 0.07 2345 13094 2 859.516836 430.7656 Transcription elongation regulator 1 OS=Homo sapiens OX=9606 GN=TCERG1 PE=1 SV=2 8.59 2912.4 - 1.78E+06 - - - 0.1117 - 1.274 0.096 - 141 1 2 0 0.0001 7 0 0 0 8.57E+07 1.27E+09 - - - 0.5173 0.9938 221125_WJC_METTL3_EV_vs_WT_F01.13102.13102.2 0.431 12-Jul R.YLDELMK.L "sp|P46940|IQGA1_HUMAN,tr|A0A0J9YXZ5|A0A0J9YXZ5_HUMAN" 2 910.447 0.97 2351 13102 2 910.445563 456.2308 Ras GTPase-activating-like protein IQGAP1 OS=Homo sapiens OX=9606 GN=IQGAP1 PE=1 SV=1 4.37 2913.4 - 831867 - - - -1.5838 - 1.195 0.23 - 144.6 1 2 0 -0.0014 7 0 0 0 3.61E+07 3.71E+07 - - - 1.3038 0.9589 221125_WJC_METTL3_EV_vs_WT_F01.13109.13109.2 6.33 12-Jun K.VLEILGK.K "sp|P43490|NAMPT_HUMAN,tr|A0A7P0T862|A0A7P0T862_HUMAN,tr|A0A7P0T931|A0A7P0T931_HUMAN,tr|A0A7P0T8L3|A0A7P0T8L3_HUMAN,tr|A0A7P0T973|A0A7P0T973_HUMAN,tr|A0A7P0T895|A0A7P0T895_HUMAN,tr|A0A0C4DFS8|A0A0C4DFS8_HUMAN,tr|A0A7P0TAS5|A0A7P0TAS5_HUMAN,tr|A0A7P0T9I9|A0A7P0T9I9_HUMAN,tr|A0A7P0T8D2|A0A7P0T8D2_HUMAN" 10 770.4902 0.92 2356 13109 2 770.489155 386.2524 Nicotinamide phosphoribosyltransferase OS=Homo sapiens OX=9606 GN=NAMPT PE=1 SV=1 5.97 2914.3 - 744243 - - - -1.3446 - 1.238 0.026 - 143.6 1 2 0 -0.001 7 0 0 0 4.63E+07 5.02E+07 - - - -0.0908 0.9861 221125_WJC_METTL3_EV_vs_WT_F01.13110.13110.2 0.0033 16-Sep K.PLYVALAQR[166.11].K "sp|Q13310|PABP4_HUMAN,sp|Q9H361|PABP3_HUMAN,sp|Q4VXU2|PAP1L_HUMAN,sp|P11940|PABP1_HUMAN,tr|A0A7I2V5W9|A0A7I2V5W9_HUMAN,tr|H0YEU6|H0YEU6_HUMAN,tr|A0A7I2YQE4|A0A7I2YQE4_HUMAN,tr|A0A7I2V649|A0A7I2V649_HUMAN,tr|B1ANR0|B1ANR0_HUMAN,tr|A0A6Q8JFT6|A0A6Q8JFT6_HUMAN,tr|A0A7I2V4L7|A0A7I2V4L7_HUMAN,tr|H0YB86|H0YB86_HUMAN,tr|H0YAR2|H0YAR2_HUMAN,tr|E7ERJ7|E7ERJ7_HUMAN,tr|A0A7I2V598|A0A7I2V598_HUMAN,tr|A0A7I2YQ88|A0A7I2YQ88_HUMAN,tr|A0A7I2V4V6|A0A7I2V4V6_HUMAN,tr|H0Y5F5|H0Y5F5_HUMAN,tr|A0A6I8PIK9|A0A6I8PIK9_HUMAN,tr|A0A6I8PS38|A0A6I8PS38_HUMAN,tr|A0A6I8PLA1|A0A6I8PLA1_HUMAN,tr|A0A087WTT1|A0A087WTT1_HUMAN,tr|A0A7I2YQ90|A0A7I2YQ90_HUMAN,tr|A0A7I2V4N4|A0A7I2V4N4_HUMAN,tr|E7EQV3|E7EQV3_HUMAN" 25 1039.6054 1.5 2357 13110 2 1039.604636 520.81 Polyadenylate-binding protein 4 OS=Homo sapiens OX=9606 GN=PABPC4 PE=1 SV=1 9.18 2914.3 - 4.47E+06 - - - -0.7205 - 1.911 0.414 - 358.2 1 1 0 -0.0007 9 0 0 0 2.95E+08 1.97E+08 - - - 3.9722 0.9884 221125_WJC_METTL3_EV_vs_WT_F01.13113.13113.2 1.78 12-Jul K.VLEILGK[136.11].K "sp|P43490|NAMPT_HUMAN,tr|A0A7P0T862|A0A7P0T862_HUMAN,tr|A0A7P0T931|A0A7P0T931_HUMAN,tr|A0A7P0T8L3|A0A7P0T8L3_HUMAN,tr|A0A7P0T973|A0A7P0T973_HUMAN,tr|A0A7P0T895|A0A7P0T895_HUMAN,tr|A0A0C4DFS8|A0A0C4DFS8_HUMAN,tr|A0A7P0TAS5|A0A7P0TAS5_HUMAN,tr|A0A7P0T9I9|A0A7P0T9I9_HUMAN,tr|A0A7P0T8D2|A0A7P0T8D2_HUMAN" 10 778.5044 1.08 2358 13113 2 778.503216 390.2595 Nicotinamide phosphoribosyltransferase OS=Homo sapiens OX=9606 GN=NAMPT PE=1 SV=1 5.97 2914.7 - 620090 - - - -1.5093 - 1.317 0.123 - 166.3 1 2 0 -0.0012 7 0 0 0 4.17E+07 3.85E+07 - - - 0.8216 0.9976 221125_WJC_METTL3_EV_vs_WT_F01.13115.13115.2 0.166 16-Aug R.LIEVTGLAR[166.11].S sp|Q9Y6X8|ZHX2_HUMAN 1 980.5894 5.13 2359 13115 2 980.589048 491.302 Zinc fingers and homeoboxes protein 2 OS=Homo sapiens OX=9606 GN=ZHX2 PE=1 SV=1 6 2915 - 455689 - - - -0.36 - 1.514 0.192 - 191.6 1 2 0 -0.0004 9 0 0 0 6.73E+07 1.31E+07 - - - 1.6589 0.9928 221125_WJC_METTL3_EV_vs_WT_F01.13117.13117.2 0.975 12-Jun K.LIVYLQR.F "sp|Q9BU02|THTPA_HUMAN,tr|G3V5Q5|G3V5Q5_HUMAN,tr|H0YJU8|H0YJU8_HUMAN" 3 903.5542 0.97 2360 13117 2 903.552978 452.7844 Thiamine-triphosphatase OS=Homo sapiens OX=9606 GN=THTPA PE=1 SV=3 8.75 2915.2 - 427836 - - - -1.3392 - 1.298 0.165 - 106.3 1 2 0 -0.0012 7 0 0 0 1.06E+07 1.09E+07 - - - 1.0857 0.9867 221125_WJC_METTL3_EV_vs_WT_F01.13119.13119.2 1.66 12-Jun K.AMVLELK[136.11].Q "sp|Q9Y5A7|NUB1_HUMAN,tr|H3BM74|H3BM74_HUMAN,tr|C9JRT6|C9JRT6_HUMAN,tr|H3BM14|H3BM14_HUMAN,tr|F8WDB6|F8WDB6_HUMAN" 5 810.4765 0.9 2362 13119 2 810.475306 406.2455 NEDD8 ultimate buster 1 OS=Homo sapiens OX=9606 GN=NUB1 PE=1 SV=2 6.05 2915.4 - 614881 - - - -1.4251 - 1.114 0.177 - 90.1 1 2 0 -0.0012 7 0 0 0 1.74E+07 1.94E+07 - - - 0.69 0.9925 221125_WJC_METTL3_EV_vs_WT_F01.13120.13120.2 0.423 12-Jun K.ILEVDLK[136.11].N "sp|Q08170|SRSF4_HUMAN,sp|Q13247|SRSF6_HUMAN,tr|S4R2X6|S4R2X6_HUMAN,tr|A0A590UK80|A0A590UK80_HUMAN,tr|A0A590UJK4|A0A590UJK4_HUMAN,tr|A0A590UJP7|A0A590UJP7_HUMAN,tr|A0A0D9SEM4|A0A0D9SEM4_HUMAN,tr|A0A590UK01|A0A590UK01_HUMAN" 8 836.5099 1.19 2363 13120 2 836.509266 419.2622 Serine\arginine-rich splicing factor 4 OS=Homo sapiens OX=9606 GN=SRSF4 PE=1 SV=2 4.37 2915.6 - 229795 - - - -0.722 - 1.093 0.21 - 94.4 1 2 0 -0.0006 7 0 0 0 2.53E+08 2.13E+08 - - - 0.8736 0.9975 221125_WJC_METTL3_EV_vs_WT_F01.13129.13129.2 0.0596 14-Jun R.YDVYLYDR[166.11].L "sp|Q9Y6Y8|S23IP_HUMAN,tr|H7C4C4|H7C4C4_HUMAN,tr|H7C0V8|H7C0V8_HUMAN" 3 1115.5163 0.94 2368 13129 2 1115.514988 558.7654 SEC23-interacting protein OS=Homo sapiens OX=9606 GN=SEC23IP PE=1 SV=1 4.21 2916.8 - 94159.2 - - - -1.1726 - 1.082 0.342 - 111.5 1 2 0 -0.0013 8 0 0 0 2.19E+06 2.33E+06 - - - 1.8043 0.9654 221125_WJC_METTL3_EV_vs_WT_F01.13133.13133.2 0.148 16-Jun K.VTAVPTLLK.Y "sp|Q9BRA2|TXD17_HUMAN,tr|I3L2R6|I3L2R6_HUMAN" 2 940.5957 0.78 2370 13133 2 940.599129 471.3051 Thioredoxin domain-containing protein 17 OS=Homo sapiens OX=9606 GN=TXNDC17 PE=1 SV=1 8.72 2917.2 - 214952 - - - 3.6264 - 1.28 0.184 - 73.9 1 2 0 0.0034 9 0 0 0 8.50E+06 1.09E+07 - - - 1.1131 0.8043 221125_WJC_METTL3_EV_vs_WT_F01.13136.13136.2 3.66 12-Apr R.FPPYYMR.R "sp|P67809|YBOX1_HUMAN,tr|H0Y449|H0Y449_HUMAN,tr|C9J5V9|C9J5V9_HUMAN" 3 972.4528 1.13 2372 13136 2 972.451936 487.2337 Y-box-binding protein 1 OS=Homo sapiens OX=9606 GN=YBX1 PE=1 SV=3 8.59 2917.6 - 1.26E+06 - - - -0.8463 - 0.585 0.183 - 35.6 1 2 0 -0.0008 7 0 0 0 3.78E+07 3.34E+07 - - - -1.3064 0.9953 221125_WJC_METTL3_EV_vs_WT_F01.13141.13141.2 0.441 12-Jun K.ILEVDLK.N "sp|Q08170|SRSF4_HUMAN,sp|Q13247|SRSF6_HUMAN,tr|S4R2X6|S4R2X6_HUMAN,tr|A0A590UK80|A0A590UK80_HUMAN,tr|A0A590UJK4|A0A590UJK4_HUMAN,tr|A0A590UJP7|A0A590UJP7_HUMAN,tr|A0A0D9SEM4|A0A0D9SEM4_HUMAN,tr|A0A590UK01|A0A590UK01_HUMAN" 8 828.4957 1.19 2374 13141 2 828.494471 415.2551 Serine\arginine-rich splicing factor 4 OS=Homo sapiens OX=9606 GN=SRSF4 PE=1 SV=2 4.37 2918.2 - 1.53E+06 - - - -1.4472 - 1.425 0.173 - 106.6 1 2 0 -0.0012 7 0 0 0 2.51E+08 2.11E+08 - - - 1.4406 0.848 221125_WJC_METTL3_EV_vs_WT_F01.13157.13157.2 0.0167 12-Jun F.FMDPIYR.V "sp|Q03112|MECOM_HUMAN,tr|H9KVD4|H9KVD4_HUMAN,tr|E7EUL6|E7EUL6_HUMAN,tr|A0A0C3SFZ7|A0A0C3SFZ7_HUMAN,tr|D6RFY3|D6RFY3_HUMAN,tr|H0YA13|H0YA13_HUMAN" 6 940.4477 0.21 2381 13157 2 940.447031 471.2311 Histone-lysine N-methyltransferase MECOM OS=Homo sapiens OX=9606 GN=MECOM PE=1 SV=3 5.84 2920.4 - 277190 - - - -0.6837 - 1.072 0.308 - 125.8 1 1 0 -0.0006 7 0 0 0 1.35E+07 6.50E+07 - - - 1.536 0.9993 221125_WJC_METTL3_EV_vs_WT_F01.13163.13163.2 0.0226 18-Aug R.ILEGGPILPK[136.11].K sp|Q9ULW0|TPX2_HUMAN 1 1043.647 0.75 2384 13163 2 1043.645437 522.8308 Targeting protein for Xklp2 OS=Homo sapiens OX=9606 GN=TPX2 PE=1 SV=2 6 2921.1 - 311920 - - - -1.5283 - 1.809 0.341 - 121.4 1 2 0 -0.0016 10 0 0 0 1.72E+07 2.28E+07 - - - 3.2137 0.9325 221125_WJC_METTL3_EV_vs_WT_F01.13171.13171.2 0.046 16-Oct K.PLYVALAQR.K "sp|Q13310|PABP4_HUMAN,sp|Q9H361|PABP3_HUMAN,sp|Q4VXU2|PAP1L_HUMAN,sp|P11940|PABP1_HUMAN,tr|A0A7I2V5W9|A0A7I2V5W9_HUMAN,tr|H0YEU6|H0YEU6_HUMAN,tr|A0A7I2YQE4|A0A7I2YQE4_HUMAN,tr|A0A7I2V649|A0A7I2V649_HUMAN,tr|B1ANR0|B1ANR0_HUMAN,tr|A0A6Q8JFT6|A0A6Q8JFT6_HUMAN,tr|A0A7I2V4L7|A0A7I2V4L7_HUMAN,tr|H0YB86|H0YB86_HUMAN,tr|H0YAR2|H0YAR2_HUMAN,tr|E7ERJ7|E7ERJ7_HUMAN,tr|A0A7I2V598|A0A7I2V598_HUMAN,tr|A0A7I2YQ88|A0A7I2YQ88_HUMAN,tr|A0A7I2V4V6|A0A7I2V4V6_HUMAN,tr|H0Y5F5|H0Y5F5_HUMAN,tr|A0A6I8PIK9|A0A6I8PIK9_HUMAN,tr|A0A6I8PS38|A0A6I8PS38_HUMAN,tr|A0A6I8PLA1|A0A6I8PLA1_HUMAN,tr|A0A087WTT1|A0A087WTT1_HUMAN,tr|A0A7I2YQ90|A0A7I2YQ90_HUMAN,tr|A0A7I2V4N4|A0A7I2V4N4_HUMAN,tr|E7EQV3|E7EQV3_HUMAN" 25 1029.5971 1.5 2387 13171 2 1029.594951 515.8058 Polyadenylate-binding protein 4 OS=Homo sapiens OX=9606 GN=PABPC4 PE=1 SV=1 9.18 2922.2 - 1.79E+06 - - - -2.1018 - 2.06 0.251 - 502.9 1 1 0 -0.0022 9 0 0 0 2.98E+08 1.99E+08 - - - 2.985 0.9837 221125_WJC_METTL3_EV_vs_WT_F01.13184.13184.2 0.0643 12-Jul K.MSILGVR[166.11].S "sp|Q92878|RAD50_HUMAN,tr|E7EN38|E7EN38_HUMAN,tr|A0A494BZX5|A0A494BZX5_HUMAN,tr|A0A494C1B7|A0A494C1B7_HUMAN,tr|E7ESD9|E7ESD9_HUMAN,tr|A0A494C122|A0A494C122_HUMAN,tr|E9PM98|E9PM98_HUMAN,tr|A0A494BZW0|A0A494BZW0_HUMAN" 8 784.4505 1.03 2394 13184 2 784.449845 393.2325 DNA repair protein RAD50 OS=Homo sapiens OX=9606 GN=RAD50 PE=1 SV=1 9.5 2923.7 - 942988 - - - -0.7904 - 1.404 0.033 - 116.7 1 2 0 -0.0006 7 0 0 0 3.58E+07 3.47E+07 - - - 0.3597 0.9979 221125_WJC_METTL3_EV_vs_WT_F01.13190.13190.2 0.912 18-Oct K.LAELEEALQK.A "sp|P13647|K2C5_HUMAN,tr|H0YI76|H0YI76_HUMAN" 2 1142.6183 156.98 2398 13190 2 1142.619645 572.3164 "Keratin, type II cytoskeletal 5 OS=Homo sapiens OX=9606 GN=KRT5 PE=1 SV=3" 4.25 2924.4 - 319348 - - - 1.1736 - 1.957 0.154 - 146.5 1 2 0 0.0013 10 0 0 0 1.22E+07 7.78E+04 - - - 2.0521 0.9968 221125_WJC_METTL3_EV_vs_WT_F01.13195.13195.2 2.88 14-Oct K.LAVEAVLR[166.11].L "sp|P78371|TCPB_HUMAN,tr|F8VQ14|F8VQ14_HUMAN,tr|F5GWF6|F5GWF6_HUMAN" 3 879.5417 0.51 2401 13195 2 879.540116 440.7781 T-complex protein 1 subunit beta OS=Homo sapiens OX=9606 GN=CCT2 PE=1 SV=4 6 2925 - 1.56E+07 - - - -1.826 - 1.873 0.136 - 506.9 1 2 0 -0.0016 8 0 0 0 9.48E+08 1.85E+09 - - - 1.9376 0.9055 221125_WJC_METTL3_EV_vs_WT_F01.13199.13199.2 1.88 12-Jul K.LLNVVKV.- sp|P17028|ZNF24_HUMAN 1 783.5218 0.73 2403 13199 2 783.519587 392.7682 Zinc finger protein 24 OS=Homo sapiens OX=9606 GN=ZNF24 PE=1 SV=4 8.75 2925.6 - 1.41E+06 - - - -2.8563 - 1.261 0.06 - 118 3 2 0 -0.0022 7 0 0 0 5.08E+07 6.92E+07 - - - 0.0051 0.9866 221125_WJC_METTL3_EV_vs_WT_F01.13201.13201.2 8.2 12-Aug R.LVQLLVK.A sp|P14923|PLAK_HUMAN 1 811.5531 43.29 2405 13201 2 811.552068 406.7838 Junction plakoglobin OS=Homo sapiens OX=9606 GN=JUP PE=1 SV=3 8.75 2925.8 - 958687 - - - -1.3024 - 1.657 0 - 139.1 1 2 0 -0.0011 7 0 0 0 7.38E+08 1.70E+07 - - - 0.6408 0.7774 221125_WJC_METTL3_EV_vs_WT_F01.13206.13206.2 0.432 12-Jul R.FESILPR.P sp|Q08211|DHX9_HUMAN 1 860.4756 0.96 2406 13206 2 860.475929 431.2451 ATP-dependent RNA helicase A OS=Homo sapiens OX=9606 GN=DHX9 PE=1 SV=4 6 2926.5 - 619347 - - - 0.3789 - 1.359 0.158 - 114.4 1 1 0 0.0003 7 0 0 0 4.01E+07 4.19E+07 - - - 1.1798 0.7913 221125_WJC_METTL3_EV_vs_WT_F01.13213.13213.2 0.0204 14-Aug L.FAEFGTLK[136.11].K "sp|Q86V81|THOC4_HUMAN,tr|E9PB61|E9PB61_HUMAN" 2 919.4895 0.72 2409 13213 2 919.486868 460.752 THO complex subunit 4 OS=Homo sapiens OX=9606 GN=ALYREF PE=1 SV=3 6 2927.4 - 1.14E+06 - - - -2.8287 - 1.386 0.305 - 144.3 1 1 0 -0.0026 8 0 0 0 3.49E+07 4.86E+07 - - - 2.2774 0.9455 221125_WJC_METTL3_EV_vs_WT_F01.13222.13222.2 0.0306 12-Jun K.FTAILYR[166.11].T "sp|Q8IWC1|MA7D3_HUMAN,tr|A0A0A0MRP0|A0A0A0MRP0_HUMAN" 2 892.5046 1.03 2414 13222 2 892.501713 447.2596 MAP7 domain-containing protein 3 OS=Homo sapiens OX=9606 GN=MAP7D3 PE=1 SV=2 8.75 2928.4 - 2.55E+06 - - - -3.2448 - 1.456 0.065 - 133.7 2 2 0 -0.0029 7 0 0 0 1.80E+08 1.74E+08 - - - 0.5761 0.9491 221125_WJC_METTL3_EV_vs_WT_F01.13228.13228.2 0.392 12-Aug K.LVYILNR[166.11].D sp|Q15393|SF3B3_HUMAN 1 899.5468 1.11 2416 13228 2 899.542447 450.7807 Splicing factor 3B subunit 3 OS=Homo sapiens OX=9606 GN=SF3B3 PE=1 SV=4 8.75 2929.2 - 772977 - - - -4.848 - 1.227 0.239 - 249.3 1 2 0 -0.0044 7 0 0 0 2.58E+08 2.33E+08 - - - 1.4531 0.9999 221125_WJC_METTL3_EV_vs_WT_F01.13243.13243.2 2.09E-05 18-Oct K.NMQDMVEDYR.N sp|P04264|K2C1_HUMAN 1 1299.5224 999 2421 13243 2 1299.521599 650.7685 "Keratin, type II cytoskeletal 1 OS=Homo sapiens OX=9606 GN=KRT1 PE=1 SV=6" 4.03 2931.3 - 531522 - - - -0.5948 - 1.784 0.617 - 395.3 1 2 0 -0.0008 10 0 0 0 1.74E+07 0.00E+00 - - - 5.2137 0.9785 221125_WJC_METTL3_EV_vs_WT_F01.13251.13251.2 1.13 12-Jul K.LLNPLVR[166.11].Q "sp|Q9Y3S1|WNK2_HUMAN,tr|H0Y7J9|H0Y7J9_HUMAN,tr|H0Y493|H0Y493_HUMAN,tr|F8W9F9|F8W9F9_HUMAN,tr|H0Y7R3|H0Y7R3_HUMAN,tr|E9PCD1|E9PCD1_HUMAN,tr|H0Y7T5|H0Y7T5_HUMAN" 7 833.5362 1.14 2425 13251 2 833.534219 417.7754 Serine\threonine-protein kinase WNK2 OS=Homo sapiens OX=9606 GN=WNK2 PE=1 SV=4 9.75 2932.3 - 946560 - - - -2.4282 - 1.264 0.141 - 127.6 1 2 0 -0.002 7 0 0 0 3.67E+07 3.22E+07 - - - 0.8241 0.9948 221125_WJC_METTL3_EV_vs_WT_F01.13256.13256.2 0.0504 12-Aug K.LVYILNR.D sp|Q15393|SF3B3_HUMAN 1 889.5385 1.11 2428 13256 2 889.536293 445.7765 Splicing factor 3B subunit 3 OS=Homo sapiens OX=9606 GN=SF3B3 PE=1 SV=4 8.75 2933 - 5.70E+06 - - - -2.5238 - 1.333 0.27 - 277.7 1 2 0 -0.0022 7 0 0 0 2.59E+08 2.33E+08 - - - 1.9453 0.943 221125_WJC_METTL3_EV_vs_WT_F01.13269.13269.2 0.748 18-Jul R.VPGATMLLAK[136.11].L sp|Q02252|MMSA_HUMAN 1 1007.5929 2.23 2436 13269 2 1007.59246 504.8037 "Methylmalonate-semialdehyde dehydrogenase [acylating], mitochondrial OS=Homo sapiens OX=9606 GN=ALDH6A1 PE=1 SV=2" 8.72 2934.5 - 390437 - - - -0.4248 - 1.23 0.011 - 105.1 3 2 0 -0.0004 10 0 0 0 3.48E+07 1.56E+07 - - - -0.5132 0.8293 221125_WJC_METTL3_EV_vs_WT_F01.13276.13276.2 1.33 18-Jul C.VLGASSGNLR[166.11].T sp|Q86YW7|GPHB5_HUMAN 1 982.5435 1.87 2441 13276 2 982.544713 492.279 Glycoprotein hormone beta-5 OS=Homo sapiens OX=9606 GN=GPHB5 PE=1 SV=1 9.72 2935.4 - 982126 - - - 1.2213 - 1.635 0.171 - 114.6 1 1 0 0.0012 10 0 0 0 8.81E+07 4.72E+07 - - - 1.676 0.9985 221125_WJC_METTL3_EV_vs_WT_F01.13285.13285.2 0.043 16-Aug R.VLLLEAGPK[136.11].D "sp|Q8NE62|CHDH_HUMAN,tr|C9J7D8|C9J7D8_HUMAN,tr|C9JYW4|C9JYW4_HUMAN" 3 946.5943 0.71 2448 13285 2 946.596657 474.3044 "Choline dehydrogenase, mitochondrial OS=Homo sapiens OX=9606 GN=CHDH PE=1 SV=2" 5.97 2936.5 - 352822 - - - 2.5238 - 1.606 0.366 - 142.1 1 2 0 0.0024 9 0 0 0 6.12E+06 8.59E+06 - - - 3.1141 0.9918 221125_WJC_METTL3_EV_vs_WT_F01.13296.13296.2 1.65 12-Jun R.ISPLQFR[166.11].- "sp|P53621|COPA_HUMAN,sp|Q12770|SCAP_HUMAN,tr|A0A3B3ISC6|A0A3B3ISC6_HUMAN,tr|A0A3B3IS84|A0A3B3IS84_HUMAN,tr|A0A0A0MTG6|A0A0A0MTG6_HUMAN,tr|A0A3B3ITI7|A0A3B3ITI7_HUMAN,tr|A0A3B3IT15|A0A3B3IT15_HUMAN" 7 869.4999 0.41 2455 13296 2 869.499275 435.7572 Coatomer subunit alpha OS=Homo sapiens OX=9606 GN=COPA PE=1 SV=2 9.75 2937.9 - 5.44E+06 - - - -0.6705 - 1.459 0.076 - 154 1 2 0 -0.0006 7 0 0 0 7.50E+07 1.82E+08 - - - 0.7991 0.9968 221125_WJC_METTL3_EV_vs_WT_F01.13306.13306.2 0.0855 14-Sep R.DLAPIGIR.V "sp|Q99714|HCD2_HUMAN,tr|A0A804HHW5|A0A804HHW5_HUMAN" 2 853.5022 0.79 2463 13306 2 853.501654 427.7584 3-hydroxyacyl-CoA dehydrogenase type-2 OS=Homo sapiens OX=9606 GN=HSD17B10 PE=1 SV=3 5.84 2939.1 - 2.25E+06 - - - -0.5835 - 1.629 0.129 - 353.6 1 2 0 -0.0005 8 0 0 0 5.89E+07 7.49E+07 - - - 1.4653 0.9993 221125_WJC_METTL3_EV_vs_WT_F01.13307.13307.2 0.733 14-Aug K.ITAFIVER.D "sp|Q9H845|ACAD9_HUMAN,tr|A0A7P0T871|A0A7P0T871_HUMAN,tr|A0A7P0T7Z1|A0A7P0T7Z1_HUMAN,tr|A0A7P0T9N9|A0A7P0T9N9_HUMAN,tr|A0A7P0T8U3|A0A7P0T8U3_HUMAN,tr|A0A7P0TB58|A0A7P0TB58_HUMAN,tr|Q9H9W4|Q9H9W4_HUMAN,tr|H0Y8Z9|H0Y8Z9_HUMAN" 8 947.544 0.66 2464 13307 2 947.544082 474.7793 "Complex I assembly factor ACAD9, mitochondrial OS=Homo sapiens OX=9606 GN=ACAD9 PE=1 SV=1" 6 2939.2 - 943063 - - - 0.0686 - 1.769 0.264 - 178.9 1 2 0 0.0001 8 0 0 0 3.01E+07 4.56E+07 - - - 2.7112 0.9956 221125_WJC_METTL3_EV_vs_WT_F01.13308.13308.2 0.422 12-Jul R.TIPVVFK.D "sp|P25685|DNJB1_HUMAN,tr|A0A7I2V3K7|A0A7I2V3K7_HUMAN" 2 802.4953 0.64 2465 13308 2 802.495443 402.2549 DnaJ homolog subfamily B member 1 OS=Homo sapiens OX=9606 GN=DNAJB1 PE=1 SV=4 8.41 2939.3 - 537353 - - - 0.2081 - 1.204 0.213 - 191.7 1 2 0 0.0002 7 0 0 0 1.75E+07 2.72E+07 - - - 1.2024 0.9982 221125_WJC_METTL3_EV_vs_WT_F01.13312.13312.2 0.487 12-Jun K.VIVFLNK.V sp|Q7Z5H4|VN1R5_HUMAN 1 831.5218 1070.67 2467 13312 2 831.521831 416.7682 Vomeronasal type-1 receptor 5 OS=Homo sapiens OX=9606 GN=VN1R5 PE=2 SV=2 8.72 2939.9 - 1.50E+06 - - - 0.0072 - 1.19 0.306 - 93.3 1 2 0 0 7 0 0 0 2.19E+08 2.05E+05 - - - 1.8523 0.999 221125_WJC_METTL3_EV_vs_WT_F01.13318.13318.2 0.0436 14-Aug K.LALDYGIK.F "sp|P61006|RAB8A_HUMAN,sp|Q92930|RAB8B_HUMAN,tr|H0YNE9|H0YNE9_HUMAN" 3 891.5066 2.89 2471 13318 2 891.506214 446.7606 Ras-related protein Rab-8A OS=Homo sapiens OX=9606 GN=RAB8A PE=1 SV=1 5.83 2940.6 - 5.42E+06 - - - -0.3982 - 1.667 0.246 - 163.5 1 2 0 -0.0004 8 0 0 0 6.30E+08 2.18E+08 - - - 2.3991 0.9993 221125_WJC_METTL3_EV_vs_WT_F01.13319.13319.2 0.573 14-Aug K.LALDYGIK[136.11].F "sp|P61006|RAB8A_HUMAN,sp|Q92930|RAB8B_HUMAN,tr|H0YNE9|H0YNE9_HUMAN" 3 899.5208 2.47 2472 13319 2 899.519815 450.7677 Ras-related protein Rab-8A OS=Homo sapiens OX=9606 GN=RAB8A PE=1 SV=1 5.83 2940.7 - 5.25E+06 - - - -1.0606 - 1.7 0.314 - 180.3 1 2 0 -0.001 8 0 0 0 5.37E+08 2.18E+08 - - - 2.9603 0.9975 221125_WJC_METTL3_EV_vs_WT_F01.13331.13331.2 0.0561 12-Jun R.YYFEGIK[136.11].Q "sp|O95433|AHSA1_HUMAN,tr|H0YJU2|H0YJU2_HUMAN,tr|G3V438|G3V438_HUMAN" 3 926.4629 1.36 2480 13331 2 926.46265 464.2387 Activator of 90 kDa heat shock protein ATPase homolog 1 OS=Homo sapiens OX=9606 GN=AHSA1 PE=1 SV=1 6 2942.1 - 373083 - - - -0.2914 - 1.134 0.296 - 96.6 1 2 0 -0.0003 7 0 0 0 7.13E+07 5.23E+07 - - - 1.6256 0.9977 221125_WJC_METTL3_EV_vs_WT_F01.13333.13333.2 3.59 14-Aug K.LAVEAVLR.L "sp|P78371|TCPB_HUMAN,tr|F8VQ14|F8VQ14_HUMAN,tr|F5GWF6|F5GWF6_HUMAN" 3 869.5335 0.48 2482 13333 2 869.532504 435.774 T-complex protein 1 subunit beta OS=Homo sapiens OX=9606 GN=CCT2 PE=1 SV=4 6 2942.2 - 4.14E+06 - - - -1.0902 - 1.673 0.169 - 209.4 1 2 0 -0.0009 8 0 0 0 1.22E+08 2.54E+08 - - - 1.841 0.9996 221125_WJC_METTL3_EV_vs_WT_F01.13335.13335.2 0.00292 14-Aug K.VLVPQIPR[166.11].L sp|Q10469|MGAT2_HUMAN 1 930.589 1.36 2484 13335 2 930.589279 466.3018 "Alpha-1,6-mannosyl-glycoprotein 2-beta-N-acetylglucosaminyltransferase OS=Homo sapiens OX=9606 GN=MGAT2 PE=1 SV=1" 9.72 2942.5 - 300958 - - - 0.2923 - 1.64 0.366 - 232.7 1 2 0 0.0003 8 0 0 0 1.37E+08 1.01E+08 - - - 3.2362 0.8699 221125_WJC_METTL3_EV_vs_WT_F01.13340.13340.2 1.19 18-Aug K.PLIPTEASIR.V "sp|Q9BUK6|MSTO1_HUMAN,tr|A0A3B3IUD2|A0A3B3IUD2_HUMAN" 2 1095.6288 2.48 2486 13340 2 1095.627044 548.8217 Protein misato homolog 1 OS=Homo sapiens OX=9606 GN=MSTO1 PE=1 SV=1 6.43 2943.2 - 393704 - - - -1.6109 - 1.574 0.233 - 188.2 1 1 0 -0.0018 10 0 0 0 1.64E+07 6.61E+06 - - - 2.0276 0.9877 221125_WJC_METTL3_EV_vs_WT_F01.13346.13346.2 0.886 14-Jul R.LYELDGLR[166.11].E "sp|Q9Y5K5|UCHL5_HUMAN,tr|H0Y4E0|H0Y4E0_HUMAN,tr|Q5LJA9|Q5LJA9_HUMAN,tr|H0Y6Y4|H0Y6Y4_HUMAN,tr|Q5LJB0|Q5LJB0_HUMAN,tr|Q5LJA5|Q5LJA5_HUMAN" 6 987.5265 0.63 2489 13346 2 987.525493 494.7705 Ubiquitin carboxyl-terminal hydrolase isozyme L5 OS=Homo sapiens OX=9606 GN=UCHL5 PE=1 SV=3 4.37 2944 - 198899 - - - -0.9853 - 1.337 0.092 - 99 1 2 0 -0.001 8 0 0 0 2.04E+07 3.24E+07 - - - 0.5961 0.9993 221125_WJC_METTL3_EV_vs_WT_F01.13359.13359.2 0.0254 12-May K.LFEMAYK[136.11].K "sp|P38646|GRP75_HUMAN,tr|A0A7I2V2S7|A0A7I2V2S7_HUMAN,tr|A0A7I2V2G2|A0A7I2V2G2_HUMAN,tr|A0A7I2V3F7|A0A7I2V3F7_HUMAN,tr|A0A7I2YQB2|A0A7I2YQB2_HUMAN,tr|D6RCD7|D6RCD7_HUMAN" 6 908.4557 0.37 2497 13359 2 908.455633 455.2351 "Stress-70 protein, mitochondrial OS=Homo sapiens OX=9606 GN=HSPA9 PE=1 SV=2" 6 2945.6 - 5.43E+06 - - - -0.1024 - 1.345 0.362 - 93.5 1 2 0 -0.0001 7 0 0 0 6.81E+08 1.83E+09 - - - 2.6538 0.9904 221125_WJC_METTL3_EV_vs_WT_F01.13360.13360.2 0.0616 14-Aug R.LATEFELR.K sp|A5YKK6|CNOT1_HUMAN 1 977.5182 0.65 2498 13360 2 977.517438 489.7664 CCR4-NOT transcription complex subunit 1 OS=Homo sapiens OX=9606 GN=CNOT1 PE=1 SV=2 4.53 2945.7 - 347506 - - - -0.7754 - 1.649 0.022 - 176.9 1 2 0 -0.0008 8 0 0 0 2.01E+07 3.08E+07 - - - 0.7117 0.9542 221125_WJC_METTL3_EV_vs_WT_F01.13363.13363.2 3.91 14-May R.IPTSTPLR.D "sp|Q14159|SPIDR_HUMAN,tr|H0YBC9|H0YBC9_HUMAN,tr|E5RGX8|E5RGX8_HUMAN" 3 883.5127 1.54 2499 13363 2 883.513117 442.7636 DNA repair-scaffolding protein OS=Homo sapiens OX=9606 GN=SPIDR PE=1 SV=2 9.75 2946.2 - 4.31E+06 - - - 0.4527 - 1.091 0.049 - 69.8 1 2 0 0.0004 8 0 0 0 7.20E+08 4.69E+08 - - - -0.3345 0.9572 221125_WJC_METTL3_EV_vs_WT_F01.13370.13370.2 0.921 12-Jul K.TISLVIR.G "sp|Q15149|PLEC_HUMAN,tr|H0YDN1|H0YDN1_HUMAN" 2 800.512 1.63 2504 13370 2 800.513987 401.2633 Plectin OS=Homo sapiens OX=9606 GN=PLEC PE=1 SV=3 9.41 2947 - 818332 - - - 2.4959 - 1.374 0.049 - 165.1 1 2 0 0.002 7 0 0 0 2.73E+07 1.67E+07 - - - 0.409 0.8966 221125_WJC_METTL3_EV_vs_WT_F01.13373.13373.2 2.7 20-Jun K.LLSMAYSAVGK[136.11].L "sp|Q5VYK3|ECM29_HUMAN,tr|J3KN16|J3KN16_HUMAN,tr|A0A804HJA4|A0A804HJA4_HUMAN,tr|R4GMY1|R4GMY1_HUMAN" 4 1146.6198 0.73 2507 13373 2 1146.622041 574.3172 Proteasome adapter and scaffold protein ECM29 OS=Homo sapiens OX=9606 GN=ECPAS PE=1 SV=2 8.59 2947.4 - 135488 - - - 1.9274 - 1.13 0.027 - 65.5 1 2 0 0.0022 11 0 0 0 4.12E+06 5.68E+06 - - - -0.4296 0.9995 221125_WJC_METTL3_EV_vs_WT_F01.13376.13376.2 0.0097 12-Jul K.LFEMAYK.K "sp|P38646|GRP75_HUMAN,tr|A0A7I2V2S7|A0A7I2V2S7_HUMAN,tr|A0A7I2V2G2|A0A7I2V2G2_HUMAN,tr|A0A7I2V3F7|A0A7I2V3F7_HUMAN,tr|A0A7I2YQB2|A0A7I2YQB2_HUMAN,tr|D6RCD7|D6RCD7_HUMAN" 6 900.4415 0.37 2508 13376 2 900.441437 451.228 "Stress-70 protein, mitochondrial OS=Homo sapiens OX=9606 GN=HSPA9 PE=1 SV=2" 6 2947.8 - 6.60E+06 - - - -0.0988 - 1.443 0.389 - 145.1 1 2 0 -0.0001 7 0 0 0 6.81E+08 1.83E+09 - - - 3.0761 0.9784 221125_WJC_METTL3_EV_vs_WT_F01.13386.13386.2 1.16 12-Jun K.ESPLLFK[136.11].F "sp|P26038|MOES_HUMAN,tr|V9GZ54|V9GZ54_HUMAN" 2 840.4837 0.63 2514 13386 2 840.481982 421.2491 Moesin OS=Homo sapiens OX=9606 GN=MSN PE=1 SV=3 6.1 2949.1 - 775800 - - - -1.9905 - 1.225 0.125 - 120.2 1 2 0 -0.0017 7 0 0 0 1.35E+07 2.15E+07 - - - 0.6068 0.9999 221125_WJC_METTL3_EV_vs_WT_F01.13388.13388.2 8.39E-05 22-Oct R.TVIIEQSWGSPK[136.11].V "sp|P10809|CH60_HUMAN,tr|C9JL25|C9JL25_HUMAN,tr|A0A7I2V2X6|A0A7I2V2X6_HUMAN,tr|A0A7I2YQK6|A0A7I2YQK6_HUMAN,tr|A0A7I2V599|A0A7I2V599_HUMAN,tr|E7EXB4|E7EXB4_HUMAN,tr|C9JL19|C9JL19_HUMAN,tr|A0A7I2YQ71|A0A7I2YQ71_HUMAN,tr|E7ESH4|E7ESH4_HUMAN,tr|A0A7I2V5M1|A0A7I2V5M1_HUMAN,tr|A0A7I2V5K3|A0A7I2V5K3_HUMAN,tr|A0A7I2V369|A0A7I2V369_HUMAN,tr|C9JCQ4|C9JCQ4_HUMAN" 13 1351.7227 1.29 2516 13388 2 1351.723581 676.8686 "60 kDa heat shock protein, mitochondrial OS=Homo sapiens OX=9606 GN=HSPD1 PE=1 SV=2" 5.66 2949.4 - 140514 - - - 0.6399 - 2.175 0.499 - 294.8 1 2 0 0.0009 12 0 0 0 1.45E+07 1.13E+07 - - - 4.7708 0.9597 221125_WJC_METTL3_EV_vs_WT_F01.13396.13396.2 0.645 16-Aug R.IIFSPVAPK.E sp|O15294|OGT1_HUMAN 1 970.5852 2.35 2520 13396 2 970.588734 486.2999 UDP-N-acetylglucosamine--peptide N-acetylglucosaminyltransferase 110 kDa subunit OS=Homo sapiens OX=9606 GN=OGT PE=1 SV=3 8.75 2950.5 - 2.52E+06 - - - 3.6885 - 1.366 0.166 - 103.7 2 2 0 0.0036 9 0 0 0 1.34E+08 5.69E+07 - - - 1.0338 0.998 221125_WJC_METTL3_EV_vs_WT_F01.13407.13407.2 0.0551 12-Jun R.LVWYC[160.03]AR[166.11].C "sp|Q96CB8|INT12_HUMAN,tr|A0A087WXN4|A0A087WXN4_HUMAN" 2 976.4828 0.89 2526 13407 2 976.482074 489.2487 Integrator complex subunit 12 OS=Homo sapiens OX=9606 GN=INTS12 PE=1 SV=1 8.22 2951.8 - 1.16E+06 - - - -0.7722 - 1.16 0.318 - 127.8 1 2 0 -0.0008 7 0 0 0 4.29E+07 4.81E+07 - - - 1.8598 0.8528 221125_WJC_METTL3_EV_vs_WT_F01.13410.13410.2 0.797 14-Jul K.IAADILIK.E "sp|Q9H583|HEAT1_HUMAN,tr|Q5T3Q7|Q5T3Q7_HUMAN" 2 855.543 0.98 2529 13410 2 855.538567 428.7788 HEAT repeat-containing protein 1 OS=Homo sapiens OX=9606 GN=HEATR1 PE=1 SV=3 5.84 2952.1 - 242989 - - - -5.1277 - 1.433 0.141 - 90 8 2 0 -0.0044 8 0 0 0 1.05E+07 1.07E+07 - - - 0.7627 0.9482 221125_WJC_METTL3_EV_vs_WT_F01.13412.13412.2 0.0318 16-Sep K.PLYVALAQR.K "sp|Q13310|PABP4_HUMAN,sp|Q9H361|PABP3_HUMAN,sp|Q4VXU2|PAP1L_HUMAN,sp|P11940|PABP1_HUMAN,tr|A0A7I2V5W9|A0A7I2V5W9_HUMAN,tr|H0YEU6|H0YEU6_HUMAN,tr|A0A7I2YQE4|A0A7I2YQE4_HUMAN,tr|A0A7I2V649|A0A7I2V649_HUMAN,tr|B1ANR0|B1ANR0_HUMAN,tr|A0A6Q8JFT6|A0A6Q8JFT6_HUMAN,tr|A0A7I2V4L7|A0A7I2V4L7_HUMAN,tr|H0YB86|H0YB86_HUMAN,tr|H0YAR2|H0YAR2_HUMAN,tr|E7ERJ7|E7ERJ7_HUMAN,tr|A0A7I2V598|A0A7I2V598_HUMAN,tr|A0A7I2YQ88|A0A7I2YQ88_HUMAN,tr|A0A7I2V4V6|A0A7I2V4V6_HUMAN,tr|H0Y5F5|H0Y5F5_HUMAN,tr|A0A6I8PIK9|A0A6I8PIK9_HUMAN,tr|A0A6I8PS38|A0A6I8PS38_HUMAN,tr|A0A6I8PLA1|A0A6I8PLA1_HUMAN,tr|A0A087WTT1|A0A087WTT1_HUMAN,tr|A0A7I2YQ90|A0A7I2YQ90_HUMAN,tr|A0A7I2V4N4|A0A7I2V4N4_HUMAN,tr|E7EQV3|E7EQV3_HUMAN" 25 1029.5971 1.53 2530 13412 2 1029.598779 515.8058 Polyadenylate-binding protein 4 OS=Homo sapiens OX=9606 GN=PABPC4 PE=1 SV=1 9.18 2952.3 - 243009 - - - 1.6162 - 1.728 0.326 - 329.5 1 1 0 0.0017 9 0 0 0 1.41E+07 9.21E+06 - - - 3.0307 0.9953 221125_WJC_METTL3_EV_vs_WT_F01.13419.13419.2 0.485 14-Aug R.LPLATIVK.D sp|O94776|MTA2_HUMAN 1 853.5637 0.94 2533 13419 2 853.563316 427.7891 Metastasis-associated protein MTA2 OS=Homo sapiens OX=9606 GN=MTA2 PE=1 SV=1 8.75 2953.3 - 335082 - - - -0.4382 - 1.349 0.164 - 117.5 1 2 0 -0.0004 8 0 0 0 1.43E+08 1.52E+08 - - - 1.1551 0.9966 221125_WJC_METTL3_EV_vs_WT_F01.13440.13440.2 1.28 12-Sep R.LVQLLVK.A sp|P14923|PLAK_HUMAN 1 811.5531 30.22 2540 13440 2 811.552046 406.7838 Junction plakoglobin OS=Homo sapiens OX=9606 GN=JUP PE=1 SV=3 8.75 2956.1 - 727235 - - - -1.3295 - 1.817 0.097 - 218.5 1 2 0 -0.0011 7 0 0 0 7.48E+07 2.47E+06 - - - 1.6493 0.7877 221125_WJC_METTL3_EV_vs_WT_F01.13442.13442.2 1.34 20-Apr R.LVGTPGAELLK[136.11].K "sp|Q16539|MK14_HUMAN,tr|B4E0K5|B4E0K5_HUMAN" 2 1104.6634 0.36 2541 13442 2 1104.66043 553.339 Mitogen-activated protein kinase 14 OS=Homo sapiens OX=9606 GN=MAPK14 PE=1 SV=3 6 2956.3 - 116136 - - - -2.6986 - 0.939 0.093 - 29.1 3 2 0 -0.003 11 0 0 0 1.68E+06 4.71E+06 - - - -0.6564 0.9957 221125_WJC_METTL3_EV_vs_WT_F01.13444.13444.2 0.9 14-Sep K.LAVEAVLR[166.11].L "sp|P78371|TCPB_HUMAN,tr|F8VQ14|F8VQ14_HUMAN,tr|F5GWF6|F5GWF6_HUMAN" 3 879.5417 0.48 2542 13444 2 879.541772 440.7781 T-complex protein 1 subunit beta OS=Homo sapiens OX=9606 GN=CCT2 PE=1 SV=4 6 2956.6 - 7.39E+06 - - - 0.0568 - 1.649 0.09 - 382.4 1 2 0 0.0001 8 0 0 0 2.22E+08 4.64E+08 - - - 1.2142 0.9975 221125_WJC_METTL3_EV_vs_WT_F01.13445.13445.2 0.111 14-Jul R.LPLATIVK[136.11].D sp|O94776|MTA2_HUMAN 1 861.5779 0.94 2543 13445 2 861.577671 431.7962 Metastasis-associated protein MTA2 OS=Homo sapiens OX=9606 GN=MTA2 PE=1 SV=1 8.75 2956.7 - 607788 - - - -0.2542 - 1.345 0.228 - 84.2 1 2 0 -0.0002 8 0 0 0 1.43E+08 1.53E+08 - - - 1.6188 0.999 221125_WJC_METTL3_EV_vs_WT_F01.13448.13448.2 0.366 14-Aug R.IGADFLAR.W sp|P17174|AATC_HUMAN 1 861.4709 2.33 2545 13448 2 861.471146 431.7427 "Aspartate aminotransferase, cytoplasmic OS=Homo sapiens OX=9606 GN=GOT1 PE=1 SV=3" 5.84 2957 - 588049 - - - 0.3413 - 1.541 0.275 - 114.9 1 2 0 0.0003 8 0 0 0 3.30E+07 1.42E+07 - - - 2.3763 0.9997 221125_WJC_METTL3_EV_vs_WT_F01.13450.13450.2 0.0377 18-Oct K.VLQSALAAIR[166.11].H "sp|Q12905|ILF2_HUMAN,tr|B4DY09|B4DY09_HUMAN" 2 1050.6425 1.22 2546 13450 2 1050.641958 526.3285 Interleukin enhancer-binding factor 2 OS=Homo sapiens OX=9606 GN=ILF2 PE=1 SV=2 9.72 2957.3 - 1.47E+06 - - - -0.5149 - 1.899 0.373 - 343.7 1 2 0 -0.0005 10 0 0 0 1.64E+08 1.34E+08 - - - 3.5859 0.9998 221125_WJC_METTL3_EV_vs_WT_F01.13457.13457.2 0.00468 18-Nov K.VLQSALAAIR.H "sp|Q12905|ILF2_HUMAN,tr|B4DY09|B4DY09_HUMAN" 2 1040.6342 1.22 2550 13457 2 1040.633969 521.3244 Interleukin enhancer-binding factor 2 OS=Homo sapiens OX=9606 GN=ILF2 PE=1 SV=2 9.72 2958.1 - 1.97E+06 - - - -0.2498 - 2.077 0.382 - 452.7 1 2 0 -0.0003 10 0 0 0 1.64E+08 1.34E+08 - - - 3.9026 0.9993 221125_WJC_METTL3_EV_vs_WT_F01.13470.13470.2 0.00477 18-Sep R.VLAESLGPLR[166.11].E sp|Q4KMQ1|TPRN_HUMAN 1 1063.6265 2.86 2558 13470 2 1063.626074 532.8205 Taperin OS=Homo sapiens OX=9606 GN=TPRN PE=1 SV=2 5.97 2959.7 - 843050 - - - -0.4146 - 1.702 0.287 - 276.2 1 2 0 -0.0004 10 0 0 0 1.25E+08 4.38E+07 - - - 2.6451 0.9988 221125_WJC_METTL3_EV_vs_WT_F01.13474.13474.2 2.56 14-Jul R.VLVLVPTR.E "sp|Q96GQ7|DDX27_HUMAN,tr|B7Z6D5|B7Z6D5_HUMAN,tr|A0A087X059|A0A087X059_HUMAN" 3 895.5855 0.85 2560 13474 2 895.585152 448.8 Probable ATP-dependent RNA helicase DDX27 OS=Homo sapiens OX=9606 GN=DDX27 PE=1 SV=2 9.72 2960.3 - 633879 - - - -0.3752 - 1.55 0.249 - 197.2 1 2 0 -0.0003 8 0 0 0 3.02E+07 3.57E+07 - - - 2.2018 0.9983 221125_WJC_METTL3_EV_vs_WT_F01.13475.13475.2 0.0319 16-Jul R.IIFSPVAPK[136.11].E sp|O15294|OGT1_HUMAN 1 978.5994 2.37 2561 13475 2 978.599525 490.307 UDP-N-acetylglucosamine--peptide N-acetylglucosaminyltransferase 110 kDa subunit OS=Homo sapiens OX=9606 GN=OGT PE=1 SV=3 8.75 2960.4 - 487515 - - - 0.1747 - 1.334 0.277 - 91 1 2 0 0.0002 9 0 0 0 1.34E+08 5.65E+07 - - - 1.9206 0.9995 221125_WJC_METTL3_EV_vs_WT_F01.13482.13482.2 0.0087 14-Jun R.YPEEFALR.D "sp|O60825|F262_HUMAN,sp|P16118|F261_HUMAN,tr|I1Z9G3|I1Z9G3_HUMAN,tr|Q4VBA9|Q4VBA9_HUMAN" 4 1023.5025 3.09 2566 13482 2 1023.503209 512.7585 "6-phosphofructo-2-kinase\fructose-2,6-bisphosphatase 2 OS=Homo sapiens OX=9606 GN=PFKFB2 PE=1 SV=2" 4.53 2961.3 - 190040 - - - 0.6478 - 1.401 0.418 - 146 1 2 0 0.0007 8 0 0 0 9.19E+07 2.98E+07 - - - 3.1451 0.9698 221125_WJC_METTL3_EV_vs_WT_F01.13489.13489.2 0.616 14-May K.IDVAFVDR.A sp|Q15645|PCH2_HUMAN 1 933.492 0.6 2570 13489 2 933.49165 467.7533 Pachytene checkpoint protein 2 homolog OS=Homo sapiens OX=9606 GN=TRIP13 PE=1 SV=2 4.21 2962.2 - 271401 - - - -0.3557 - 1.129 0.108 - 42 5 2 0 -0.0003 8 0 0 0 1.01E+07 1.68E+07 - - - -0.1077 0.97 221125_WJC_METTL3_EV_vs_WT_F01.13503.13503.2 3.01 14-May K.DVMQETIR[166.11].N "sp|Q9Y2A4|ZN443_HUMAN,sp|Q8N8Z8|ZN441_HUMAN,sp|Q96GE5|ZN799_HUMAN,tr|A0A0A0MSF7|A0A0A0MSF7_HUMAN,tr|F8WDY2|F8WDY2_HUMAN,tr|M0R135|M0R135_HUMAN" 6 1000.4887 0.89 2578 13503 2 1000.488385 501.2516 Zinc finger protein 443 OS=Homo sapiens OX=9606 GN=ZNF443 PE=2 SV=2 4.37 2963.9 - 1.05E+06 - - - -0.3158 - 1.132 0.065 - 127.7 1 2 0 -0.0003 8 0 0 0 1.64E+08 1.85E+08 - - - -0.1051 0.891 221125_WJC_METTL3_EV_vs_WT_F01.13513.13513.2 2.28 14-Jun K.ENEVSVVK[136.11].E "sp|O00400|ACATN_HUMAN,tr|H7C577|H7C577_HUMAN,tr|A0A2R8Y5I5|A0A2R8Y5I5_HUMAN" 3 910.4851 0.46 2583 13513 2 910.486121 456.2498 Acetyl-coenzyme A transporter 1 OS=Homo sapiens OX=9606 GN=SLC33A1 PE=1 SV=1 4.53 2965.2 - 398377 - - - 1.1082 - 1.08 0.039 - 60.3 5 2 0 0.001 8 0 0 0 6.63E+07 1.45E+08 - - - -0.7514 0.9993 221125_WJC_METTL3_EV_vs_WT_F01.13514.13514.2 0.00461 14-Oct K.IDNIVLMK[136.11].D "sp|Q86U06|RBM23_HUMAN,tr|H0YJJ3|H0YJJ3_HUMAN,tr|G3XAP0|G3XAP0_HUMAN,tr|G3V5Z6|G3V5Z6_HUMAN" 4 952.5507 1.71 2584 13514 2 952.548578 477.2826 Probable RNA-binding protein 23 OS=Homo sapiens OX=9606 GN=RBM23 PE=1 SV=1 5.84 2965.3 - 1.36E+06 - - - -2.2162 - 1.868 0.366 - 255.2 1 2 0 -0.0021 8 0 0 0 1.91E+08 1.12E+08 - - - 3.6282 0.9941 221125_WJC_METTL3_EV_vs_WT_F01.13517.13517.2 0.316 12-Jul R.SLILAMK.A sp|Q7Z353|HDX_HUMAN 1 774.4673 3.28 2585 13517 2 774.465968 388.2409 Highly divergent homeobox OS=Homo sapiens OX=9606 GN=HDX PE=1 SV=1 8.47 2965.7 - 1.64E+06 - - - -1.7806 - 1.291 0.214 - 207.9 1 2 0 -0.0014 7 0 0 0 5.95E+07 1.81E+07 - - - 1.4305 0.9991 221125_WJC_METTL3_EV_vs_WT_F01.13524.13524.2 0.00275 14-Aug K.LYLADPMK[136.11].A "sp|P49458|SRP09_HUMAN,tr|Q659G3|Q659G3_HUMAN,tr|E9PE20|E9PE20_HUMAN,tr|Q6P2S0|Q6P2S0_HUMAN" 4 957.5085 1.2 2589 13524 2 957.506211 479.7615 Signal recognition particle 9 kDa protein OS=Homo sapiens OX=9606 GN=SRP9 PE=1 SV=2 5.83 2966.6 - 2.49E+06 - - - -2.3801 - 1.625 0.408 - 158.1 1 2 0 -0.0023 8 0 0 0 4.68E+08 3.89E+08 - - - 3.518 0.9985 221125_WJC_METTL3_EV_vs_WT_F01.13526.13526.2 0.0223 12-Aug R.FTDILVR[166.11].H sp|O43143|DHX15_HUMAN 1 872.4995 1.06 2591 13526 2 872.497739 437.257 Pre-mRNA-splicing factor ATP-dependent RNA helicase DHX15 OS=Homo sapiens OX=9606 GN=DHX15 PE=1 SV=2 5.84 2966.7 - 4.68E+06 - - - -2.0447 - 1.536 0.312 - 241.2 1 2 0 -0.0018 7 0 0 0 5.50E+08 5.21E+08 - - - 2.7048 0.9801 221125_WJC_METTL3_EV_vs_WT_F01.13531.13531.2 0.489 14-Jul K.LLGPVLVK.Q "sp|O15212|PFD6_HUMAN,tr|A2AB88|A2AB88_HUMAN" 2 837.5688 2.85 2593 13531 2 837.566811 419.7917 Prefoldin subunit 6 OS=Homo sapiens OX=9606 GN=PFDN6 PE=1 SV=1 8.75 2967.3 - 1.66E+06 - - - -2.3449 - 1.413 0.102 - 88.2 1 2 0 -0.002 8 0 0 0 1.21E+09 4.27E+08 - - - 0.8364 0.999 221125_WJC_METTL3_EV_vs_WT_F01.13533.13533.2 0.0257 18-Nov K.LAEALYIADR.K "sp|Q13573|SNW1_HUMAN,tr|G3V4X8|G3V4X8_HUMAN,tr|G3V3A4|G3V3A4_HUMAN" 3 1133.6081 1.1 2594 13533 2 1133.604933 567.8113 SNW domain-containing protein 1 OS=Homo sapiens OX=9606 GN=SNW1 PE=1 SV=1 4.37 2967.5 - 270585 - - - -2.7708 - 2.093 0.354 - 330.2 1 2 0 -0.0031 10 0 0 0 7.40E+07 6.73E+07 - - - 3.7163 0.9364 221125_WJC_METTL3_EV_vs_WT_F01.13535.13535.2 1.59 12-Jul R.AWGALIK[136.11].E "sp|Q53F19|NCBP3_HUMAN,tr|K7ELP6|K7ELP6_HUMAN" 2 765.4629 0.13 2595 13535 2 765.460366 383.7387 Nuclear cap-binding protein subunit 3 OS=Homo sapiens OX=9606 GN=NCBP3 PE=1 SV=2 8.8 2967.7 - 931692 - - - -3.2582 - 1.231 0.105 - 156 1 2 0 -0.0025 7 0 0 0 6.68E+06 5.19E+07 - - - 0.4743 0.9981 221125_WJC_METTL3_EV_vs_WT_F01.13538.13538.2 0.0163 20-Jul K.VMPTLAPVVAK.L sp|Q8IWI9|MGAP_HUMAN 1 1124.6628 0.83 2598 13538 2 1124.660546 563.3387 MAX gene-associated protein OS=Homo sapiens OX=9606 GN=MGA PE=1 SV=4 8.72 2968.1 - 225590 - - - -1.9615 - 1.461 0.326 - 158.1 1 2 0 -0.0022 11 0 0 0 9.42E+06 1.13E+07 - - - 2.4738 0.9975 221125_WJC_METTL3_EV_vs_WT_F01.13542.13542.2 0.046 14-Aug R.VWAEYALK[136.11].R sp|Q6P2Q9|PRP8_HUMAN 1 986.5317 1.11 2600 13542 2 986.529102 494.2731 Pre-mRNA-processing-splicing factor 8 OS=Homo sapiens OX=9606 GN=PRPF8 PE=1 SV=2 5.97 2968.5 - 5.11E+06 - - - -2.601 - 1.498 0.32 - 225.6 1 2 0 -0.0026 8 0 0 0 2.59E+08 2.34E+08 - - - 2.6226 0.996 221125_WJC_METTL3_EV_vs_WT_F01.13545.13545.2 0.000176 13/18 K.LAEALYIADR[166.11].K "sp|Q13573|SNW1_HUMAN,tr|G3V4X8|G3V4X8_HUMAN,tr|G3V3A4|G3V3A4_HUMAN" 3 1143.6163 1.1 2603 13545 2 1143.610411 572.8154 SNW domain-containing protein 1 OS=Homo sapiens OX=9606 GN=SNW1 PE=1 SV=1 4.37 2968.9 - 284160 - - - -5.1879 - 2.374 0.372 - 803.8 1 2 0 -0.0059 10 0 0 0 7.40E+07 6.73E+07 - - - 4.2 0.9919 221125_WJC_METTL3_EV_vs_WT_F01.13551.13551.2 0.336 14-Aug K.LFVADLQR[166.11].V sp|Q92830|KAT2A_HUMAN 1 970.5475 3.01 2605 13551 2 970.544553 486.281 Histone acetyltransferase KAT2A OS=Homo sapiens OX=9606 GN=KAT2A PE=1 SV=3 5.84 2969.7 - 671072 - - - -3.0735 - 1.734 0.164 - 187.5 1 2 0 -0.003 8 0 0 0 7.55E+07 2.51E+07 - - - 1.9114 0.9997 221125_WJC_METTL3_EV_vs_WT_F01.13556.13556.2 0.00121 18-Oct R.LTPYEVDELR.R "sp|Q92841|DDX17_HUMAN,tr|A0A5H1ZRQ2|A0A5H1ZRQ2_HUMAN,tr|A0A1X7SBZ2|A0A1X7SBZ2_HUMAN" 3 1233.6241 1.23 2606 13556 2 1233.623092 617.8193 Probable ATP-dependent RNA helicase DDX17 OS=Homo sapiens OX=9606 GN=DDX17 PE=1 SV=2 4.14 2970.5 - 1.40E+06 - - - -0.8317 - 1.942 0.381 - 518.6 1 2 0 -0.001 10 0 0 0 8.49E+07 6.91E+07 - - - 3.7074 0.809 221125_WJC_METTL3_EV_vs_WT_F01.13561.13561.2 0.0138 18-Jul R.VGAGAPVYMA.A "sp|Q16777|H2A2C_HUMAN,sp|Q6FI13|H2A2A_HUMAN" 2 934.4582 - 2608 13561 2 934.456029 468.2364 Histone H2A type 2-C OS=Homo sapiens OX=9606 GN=H2AC20 PE=1 SV=4 5.49 2971.2 - 4.60E+06 - - - -2.365 - 1.123 0.368 - 100.8 1 1 0 -0.0022 10 0 0 0 - - - - - 2.0822 0.9997 221125_WJC_METTL3_EV_vs_WT_F01.13565.13565.2 0.000616 18-Sep R.LTPYEVDELR[166.11].R "sp|Q92841|DDX17_HUMAN,tr|A0A5H1ZRQ2|A0A5H1ZRQ2_HUMAN,tr|A0A1X7SBZ2|A0A1X7SBZ2_HUMAN" 3 1243.6324 1.23 2609 13565 2 1243.631852 622.8235 Probable ATP-dependent RNA helicase DDX17 OS=Homo sapiens OX=9606 GN=DDX17 PE=1 SV=2 4.14 2971.8 - 1.07E+06 - - - -0.431 - 1.934 0.381 - 351.5 1 2 0 -0.0005 10 0 0 0 8.49E+07 6.91E+07 - - - 3.696 0.9794 221125_WJC_METTL3_EV_vs_WT_F01.13569.13569.2 2.51 12-Jun R.VFDMLNR.R "sp|Q14240|IF4A2_HUMAN,sp|P60842|IF4A1_HUMAN,tr|J3KTB5|J3KTB5_HUMAN,tr|J3KT12|J3KT12_HUMAN,tr|J3QKZ9|J3QKZ9_HUMAN,tr|J3QS69|J3QS69_HUMAN,tr|J3QL43|J3QL43_HUMAN,tr|E7EQG2|E7EQG2_HUMAN,tr|J3KS25|J3KS25_HUMAN,tr|J3KSZ0|J3KSZ0_HUMAN,tr|J3QLN6|J3QLN6_HUMAN,tr|J3QR64|J3QR64_HUMAN" 12 893.4429 1.09 2611 13569 2 893.440509 447.7287 Eukaryotic initiation factor 4A-II OS=Homo sapiens OX=9606 GN=EIF4A2 PE=1 SV=2 5.81 2972.3 - 1.14E+06 - - - -2.7019 - 1.282 0.158 - 132.8 1 2 0 -0.0024 7 0 0 0 9.04E+07 8.31E+07 - - - 0.9944 0.9677 221125_WJC_METTL3_EV_vs_WT_F01.13578.13578.2 3.86 14-Jul K.LLGPVLVK[136.11].Q "sp|O15212|PFD6_HUMAN,tr|A2AB88|A2AB88_HUMAN" 2 845.583 2.85 2615 13578 2 845.581325 423.7988 Prefoldin subunit 6 OS=Homo sapiens OX=9606 GN=PFDN6 PE=1 SV=1 8.75 2973.3 - 1.28E+07 - - - -1.9513 - 1.189 0.102 - 103.3 1 2 0 -0.0016 8 0 0 0 1.21E+09 4.27E+08 - - - 0.316 0.9977 221125_WJC_METTL3_EV_vs_WT_F01.13580.13580.2 0.0253 20-Oct R.LLADPTGAFGK[136.11].E sp|P30044|PRDX5_HUMAN 1 1096.6008 1.97 2617 13580 2 1096.603795 549.3077 "Peroxiredoxin-5, mitochondrial OS=Homo sapiens OX=9606 GN=PRDX5 PE=1 SV=4" 5.84 2973.5 - 919979 - - - 2.722 - 1.834 0.29 - 228.2 1 2 0 0.003 11 0 0 0 6.62E+07 3.36E+07 - - - 2.8227 0.9995 221125_WJC_METTL3_EV_vs_WT_F01.13583.13583.2 0.0182 12-Aug R.VFDMLNR[166.11].R "sp|Q14240|IF4A2_HUMAN,sp|P60842|IF4A1_HUMAN,tr|J3KTB5|J3KTB5_HUMAN,tr|J3KT12|J3KT12_HUMAN,tr|J3QKZ9|J3QKZ9_HUMAN,tr|J3QS69|J3QS69_HUMAN,tr|J3QL43|J3QL43_HUMAN,tr|E7EQG2|E7EQG2_HUMAN,tr|J3KS25|J3KS25_HUMAN,tr|J3KSZ0|J3KSZ0_HUMAN,tr|J3QLN6|J3QLN6_HUMAN,tr|J3QR64|J3QR64_HUMAN" 12 903.4512 1.13 2618 13583 2 903.449884 452.7329 Eukaryotic initiation factor 4A-II OS=Homo sapiens OX=9606 GN=EIF4A2 PE=1 SV=2 5.81 2973.9 - 2.20E+06 - - - -1.4489 - 1.635 0.373 - 264 1 2 0 -0.0013 7 0 0 0 8.92E+07 7.87E+07 - - - 3.3534 0.9997 221125_WJC_METTL3_EV_vs_WT_F01.13591.13591.2 0.000528 14-Aug K.LYLADPMK.A "sp|P49458|SRP09_HUMAN,tr|Q659G3|Q659G3_HUMAN,tr|E9PE20|E9PE20_HUMAN,tr|Q6P2S0|Q6P2S0_HUMAN" 4 949.4943 1.17 2624 13591 2 949.492805 475.7544 Signal recognition particle 9 kDa protein OS=Homo sapiens OX=9606 GN=SRP9 PE=1 SV=2 5.83 2974.8 - 1.15E+07 - - - -1.564 - 1.772 0.445 - 274.4 1 2 0 -0.0015 8 0 0 0 4.56E+08 3.89E+08 - - - 4.0528 0.973 221125_WJC_METTL3_EV_vs_WT_F01.13599.13599.2 0.111 12-Jun R.LYFC[160.03]VDR.G "sp|O14654|IRS4_HUMAN,tr|A0A804CF45|A0A804CF45_HUMAN" 2 971.4535 0.69 2628 13599 2 971.44787 486.734 Insulin receptor substrate 4 OS=Homo sapiens OX=9606 GN=IRS4 PE=1 SV=1 5.83 2975.9 - 775250 - - - -5.7831 - 1.435 0.319 - 132.2 1 2 0 -0.0056 7 0 0 0 3.22E+07 4.67E+07 - - - 2.5397 0.8257 221125_WJC_METTL3_EV_vs_WT_F01.13600.13600.2 2.56 12-May R.TVPFLPK[136.11].Y sp|Q96EV8|DTBP1_HUMAN 1 808.4938 1.42 2629 13600 2 808.492563 405.2542 Dysbindin OS=Homo sapiens OX=9606 GN=DTNBP1 PE=1 SV=1 8.41 2975.9 - 903110 - - - -1.5622 - 0.977 0.023 - 110.1 2 2 0 -0.0013 7 0 0 0 5.41E+07 3.80E+07 - - - -0.9977 0.9936 221125_WJC_METTL3_EV_vs_WT_F01.13601.13601.2 0.327 12-Jun K.LYLEQLR.Q sp|O43818|U3IP2_HUMAN 1 933.5284 0.68 2630 13601 2 933.527997 467.7715 U3 small nucleolar RNA-interacting protein 2 OS=Homo sapiens OX=9606 GN=RRP9 PE=1 SV=1 6 2976 - 5.50E+06 - - - -0.3963 - 1.292 0.147 - 129.6 1 2 0 -0.0004 7 0 0 0 1.27E+08 1.86E+08 - - - 0.9384 0.9998 221125_WJC_METTL3_EV_vs_WT_F01.13609.13609.3 0.00048 Oct-68 R.VAPEEHPVLLTEAPLNPK.A "sp|P63261|ACTG_HUMAN,sp|P60709|ACTB_HUMAN,tr|A0A804GS07|A0A804GS07_HUMAN,tr|I3L3I0|I3L3I0_HUMAN,tr|G5E9R0|G5E9R0_HUMAN,tr|E7EVS6|E7EVS6_HUMAN,tr|A0A6Q8PFE4|A0A6Q8PFE4_HUMAN,tr|J3KT65|J3KT65_HUMAN,tr|I3L3R2|I3L3R2_HUMAN,tr|K7EM38|K7EM38_HUMAN,tr|A0A6Q8PH58|A0A6Q8PH58_HUMAN,tr|I3L1U9|I3L1U9_HUMAN,tr|A0A2R8Y793|A0A2R8Y793_HUMAN,tr|I3L4N8|I3L4N8_HUMAN,tr|A0A2R8YGF8|A0A2R8YGF8_HUMAN" 15 1953.0571 4.61 2636 13609 3 1953.056574 652.0263 "Actin, cytoplasmic 2 OS=Homo sapiens OX=9606 GN=ACTG1 PE=1 SV=1" 4.75 2977 - 151932 - - - -0.2837 - 1.968 0.382 - 75.8 1 2 0 -0.0006 18 0 0 0 3.78E+06 8.19E+05 - - - 4.4846 0.9983 221125_WJC_METTL3_EV_vs_WT_F01.13612.13612.2 0.0145 14-Sep K.LAVEAVLR.L "sp|P78371|TCPB_HUMAN,tr|F8VQ14|F8VQ14_HUMAN,tr|F5GWF6|F5GWF6_HUMAN" 3 869.5335 0.4 2637 13612 2 869.533017 435.774 T-complex protein 1 subunit beta OS=Homo sapiens OX=9606 GN=CCT2 PE=1 SV=4 6 2977.4 - 2.84E+06 - - - -0.5003 - 1.725 0.167 - 299.3 1 2 0 -0.0004 8 0 0 0 2.49E+08 6.15E+08 - - - 1.9187 0.9446 221125_WJC_METTL3_EV_vs_WT_F01.13613.13613.2 0.00651 20-Aug R.IINEPTAAAIA.Y "sp|P11021|BIP_HUMAN,sp|P54652|HSP72_HUMAN,sp|P0DMV8|HS71A_HUMAN,sp|P34931|HS71L_HUMAN,sp|P11142|HSP7C_HUMAN,sp|P0DMV9|HS71B_HUMAN,sp|P17066|HSP76_HUMAN,tr|E9PKE3|E9PKE3_HUMAN,tr|E9PN89|E9PN89_HUMAN,tr|A0A7P0TB36|A0A7P0TB36_HUMAN,tr|E9PLF4|E9PLF4_HUMAN,tr|A0A7P0TAI0|A0A7P0TAI0_HUMAN,tr|Q53FA3|Q53FA3_HUMAN,tr|E9PI65|E9PI65_HUMAN,tr|E9PK54|E9PK54_HUMAN,tr|A0A0G2JIW1|A0A0G2JIW1_HUMAN" 16 1082.5972 - 2638 13613 2 1082.596792 542.3059 Endoplasmic reticulum chaperone BiP OS=Homo sapiens OX=9606 GN=HSPA5 PE=1 SV=2 4 2977.5 - 2.82E+06 - - - -0.3538 - 1.65 0.271 - 91.3 1 1 0 -0.0004 11 0 0 0 - - - - - 2.3972 0.9921 221125_WJC_METTL3_EV_vs_WT_F01.13614.13614.2 0.669 12-Jul K.IAWALSR[166.11].K sp|Q04760|LGUL_HUMAN 1 825.4736 1.04 2639 13614 2 825.475016 413.7441 Lactoylglutathione lyase OS=Homo sapiens OX=9606 GN=GLO1 PE=1 SV=4 9.75 2977.6 - 1.84E+06 - - - 1.6633 - 1.499 0.122 - 157.7 1 2 0 0.0014 7 0 0 0 6.64E+07 6.36E+07 - - - 1.2243 0.9997 221125_WJC_METTL3_EV_vs_WT_F01.13615.13615.2 0.000408 14-Sep R.MLQAMGWK.E sp|P98175|RBM10_HUMAN 1 963.467 3.48 2640 13615 2 963.466775 482.7408 RNA-binding protein 10 OS=Homo sapiens OX=9606 GN=RBM10 PE=1 SV=3 8.5 2977.6 - 1.53E+06 - - - -0.2636 - 1.639 0.431 - 286.2 1 2 0 -0.0003 8 0 0 0 4.45E+07 1.28E+07 - - - 3.7144 0.9995 221125_WJC_METTL3_EV_vs_WT_F01.13619.13619.2 0.0842 16-Oct R.SVILISTVR[166.11].S "sp|Q9HCE1|MOV10_HUMAN,tr|Q5JR04|Q5JR04_HUMAN" 2 996.6207 0.8 2642 13619 2 996.619848 499.3176 Helicase MOV-10 OS=Homo sapiens OX=9606 GN=MOV10 PE=1 SV=2 9.47 2978.2 - 761286 - - - -0.8559 - 2.052 0.268 - 297.1 1 2 0 -0.0009 9 0 0 0 1.53E+07 1.92E+07 - - - 3.0998 0.8864 221125_WJC_METTL3_EV_vs_WT_F01.13620.13620.2 0.388 14-May K.FVDGEWYR.A sp|Q7KZF4|SND1_HUMAN 1 1070.4821 0.66 2643 13620 2 1070.484541 536.2483 Staphylococcal nuclease domain-containing protein 1 OS=Homo sapiens OX=9606 GN=SND1 PE=1 SV=1 4.37 2978.3 - 390987 - - - 2.2382 - 0.906 0.12 - 68.9 1 2 0 0.0024 8 0 0 0 7.24E+06 1.10E+07 - - - -0.3712 0.9974 221125_WJC_METTL3_EV_vs_WT_F01.13621.13621.2 0.0313 12-Jul K.LYLEQLR[166.11].Q sp|O43818|U3IP2_HUMAN 1 943.5366 0.67 2644 13621 2 943.536489 472.7756 U3 small nucleolar RNA-interacting protein 2 OS=Homo sapiens OX=9606 GN=RRP9 PE=1 SV=1 6 2978.4 - 3.51E+06 - - - -0.1569 - 1.309 0.228 - 169.1 1 2 0 -0.0001 7 0 0 0 1.27E+08 1.91E+08 - - - 1.5781 0.9998 221125_WJC_METTL3_EV_vs_WT_F01.13623.13623.2 0.000447 14-Aug K.LYLADPMK.A "sp|P49458|SRP09_HUMAN,tr|Q659G3|Q659G3_HUMAN,tr|E9PE20|E9PE20_HUMAN,tr|Q6P2S0|Q6P2S0_HUMAN" 4 949.4943 1.17 2645 13623 2 949.494865 475.7544 Signal recognition particle 9 kDa protein OS=Homo sapiens OX=9606 GN=SRP9 PE=1 SV=2 5.83 2978.6 - 5.67E+06 - - - 0.6056 - 1.758 0.44 - 276.4 1 2 0 0.0006 8 0 0 0 4.56E+08 3.89E+08 - - - 3.9922 0.9976 221125_WJC_METTL3_EV_vs_WT_F01.13632.13632.2 0.0915 14-Jul R.MLQAMGWK[136.11].E sp|P98175|RBM10_HUMAN 1 971.4812 3.69 2651 13632 2 971.481945 486.7479 RNA-binding protein 10 OS=Homo sapiens OX=9606 GN=RBM10 PE=1 SV=3 8.5 2979.7 - 729400 - - - 0.737 - 1.156 0.31 - 124.9 1 2 0 0.0007 8 0 0 0 4.33E+07 1.17E+07 - - - 1.7676 0.9995 221125_WJC_METTL3_EV_vs_WT_F01.13633.13633.2 0.162 18-Sep R.VPLVAPEDLR.D "sp|O14744|ANM5_HUMAN,tr|C9JSX3|C9JSX3_HUMAN,tr|G3V580|G3V580_HUMAN,tr|G3V2X6|G3V2X6_HUMAN,tr|G3V5L5|G3V5L5_HUMAN,tr|H0YJX6|H0YJX6_HUMAN" 6 1107.6288 3.1 2652 13633 2 1107.626342 554.8217 Protein arginine N-methyltransferase 5 OS=Homo sapiens OX=9606 GN=PRMT5 PE=1 SV=4 4.37 2979.8 - 278686 - - - -2.2273 - 2.263 0.366 - 380.5 1 2 0 -0.0025 10 0 0 0 3.08E+09 9.91E+08 - - - 4.0231 0.9982 221125_WJC_METTL3_EV_vs_WT_F01.13640.13640.2 0.118 14-Jul K.GIGLAIVR[166.11].D "sp|P16152|CBR1_HUMAN,tr|E9PQ63|E9PQ63_HUMAN,tr|A8MTM1|A8MTM1_HUMAN" 3 807.5206 1.16 2657 13640 2 807.521089 404.7676 Carbonyl reductase [NADPH] 1 OS=Homo sapiens OX=9606 GN=CBR1 PE=1 SV=3 9.75 2980.7 - 663399 - - - 0.6142 - 1.443 0.247 - 195.1 1 2 0 0.0005 8 0 0 0 1.08E+08 9.37E+07 - - - 1.9712 0.9997 221125_WJC_METTL3_EV_vs_WT_F01.13641.13641.2 9.91E-05 18-Oct R.VPLVAPEDLR[166.11].D "sp|O14744|ANM5_HUMAN,tr|C9JSX3|C9JSX3_HUMAN,tr|G3V580|G3V580_HUMAN,tr|G3V2X6|G3V2X6_HUMAN,tr|G3V5L5|G3V5L5_HUMAN,tr|H0YJX6|H0YJX6_HUMAN" 6 1117.6371 3.11 2658 13641 2 1117.638484 559.8258 Protein arginine N-methyltransferase 5 OS=Homo sapiens OX=9606 GN=PRMT5 PE=1 SV=4 4.37 2980.8 - 315327 - - - 1.2571 - 2.114 0.385 - 517 1 2 0 0.0014 10 0 0 0 3.08E+09 9.91E+08 - - - 3.9737 1 221125_WJC_METTL3_EV_vs_WT_F01.13644.13644.2 5.20E-09 13/28 K.NQVALNPQNTVFDAK[136.11].R "sp|P0DMV8|HS71A_HUMAN,sp|P0DMV9|HS71B_HUMAN,tr|A0A0G2JIW1|A0A0G2JIW1_HUMAN" 3 1665.8566 0.1 2661 13644 2 1665.858458 833.9356 Heat shock 70 kDa protein 1A OS=Homo sapiens OX=9606 GN=HSPA1A PE=1 SV=1 5.84 2981.2 - 120516 - - - 1.1249 - 2.73 0.647 - 424.4 1 2 0 0.0019 15 0 0 0 1.01E+06 1.01E+07 - - - 6.2883 0.9999 221125_WJC_METTL3_EV_vs_WT_F01.13649.13649.2 0.00045 20-Dec K.YFVEAGAMAVR[166.11].R "sp|P17987|TCPA_HUMAN,tr|F5GZ03|F5GZ03_HUMAN,tr|F5H282|F5H282_HUMAN,tr|E7EQR6|E7EQR6_HUMAN,tr|E7ERF2|E7ERF2_HUMAN" 5 1222.6044 0.38 2664 13649 2 1222.605261 612.3095 T-complex protein 1 subunit alpha OS=Homo sapiens OX=9606 GN=TCP1 PE=1 SV=1 6 2981.8 - 1.63E+06 - - - 0.7051 - 2.104 0.57 - 498.9 1 2 0 0.0009 11 0 0 0 2.07E+08 5.51E+08 - - - 5.263 0.9991 221125_WJC_METTL3_EV_vs_WT_F01.13650.13650.2 0.39 14-Sep K.GIGLAIVR.D "sp|P16152|CBR1_HUMAN,tr|E9PQ63|E9PQ63_HUMAN,tr|A8MTM1|A8MTM1_HUMAN" 3 797.5123 1.15 2665 13650 2 797.512272 399.7634 Carbonyl reductase [NADPH] 1 OS=Homo sapiens OX=9606 GN=CBR1 PE=1 SV=3 9.75 2981.9 - 987317 - - - -0.0639 - 1.76 0.238 - 269.5 1 2 0 -0.0001 8 0 0 0 1.08E+08 9.37E+07 - - - 2.5038 0.9545 221125_WJC_METTL3_EV_vs_WT_F01.13651.13651.2 2.08 12-Jul R.NLFYVER.D "sp|Q02487|DSC2_HUMAN,tr|A0A3B3ISU0|A0A3B3ISU0_HUMAN" 2 939.4814 0.04 2666 13651 2 939.483764 470.748 Desmocollin-2 OS=Homo sapiens OX=9606 GN=DSC2 PE=1 SV=1 6 2982 - 623377 - - - 2.4982 - 1.188 0.106 - 179.4 1 2 0 0.0023 7 0 0 0 1.08E+07 2.90E+08 - - - 0.369 0.9998 221125_WJC_METTL3_EV_vs_WT_F01.13653.13653.2 4.78E-06 20-Nov K.YFVEAGAMAVR.R "sp|P17987|TCPA_HUMAN,tr|F5GZ03|F5GZ03_HUMAN,tr|F5H282|F5H282_HUMAN,tr|E7EQR6|E7EQR6_HUMAN,tr|E7ERF2|E7ERF2_HUMAN" 5 1212.5961 0.38 2668 13653 2 1212.597865 607.3053 T-complex protein 1 subunit alpha OS=Homo sapiens OX=9606 GN=TCP1 PE=1 SV=1 6 2982.3 - 361782 - - - 1.4316 - 2.242 0.54 - 425.4 1 2 0 0.0017 11 0 0 0 2.07E+08 5.52E+08 - - - 5.213 0.9995 221125_WJC_METTL3_EV_vs_WT_F01.13654.13654.2 0.00121 18-Aug K.NLQEAEEWYK.S "sp|P08670|VIME_HUMAN,sp|P41219|PERI_HUMAN,tr|H7C5W5|H7C5W5_HUMAN,tr|F8W835|F8W835_HUMAN,tr|B0YJC5|B0YJC5_HUMAN,tr|B0YJC4|B0YJC4_HUMAN" 6 1308.5986 999 2669 13654 2 1308.600534 655.3066 Vimentin OS=Homo sapiens OX=9606 GN=VIM PE=1 SV=4 4.25 2982.4 - 329428 - - - 1.4535 - 1.703 0.426 - 176.6 1 2 0 0.0019 10 0 0 0 1.15E+07 0.00E+00 - - - 3.6729 0.9998 221125_WJC_METTL3_EV_vs_WT_F01.13659.13659.2 0.0018 16-Oct R.VLDELTLTK.A "sp|P13645|K1C10_HUMAN,tr|A0A1B0GVI3|A0A1B0GVI3_HUMAN" 2 1030.591 124.32 2673 13659 2 1030.591503 516.3028 "Keratin, type I cytoskeletal 10 OS=Homo sapiens OX=9606 GN=KRT10 PE=1 SV=6" 4.37 2983.1 - 1.63E+06 - - - 0.4619 - 2.164 0.438 - 352.7 1 2 0 0.0005 9 0 0 0 3.58E+07 2.88E+05 - - - 4.5092 0.9984 221125_WJC_METTL3_EV_vs_WT_F01.13670.13670.2 0.00793 16-Jul R.VPPEFLVQR[166.11].A "sp|Q13724|MOGS_HUMAN,tr|A0A3B3IRK6|A0A3B3IRK6_HUMAN,tr|A0A3B3IRW2|A0A3B3IRW2_HUMAN" 3 1093.616 3.14 2682 13670 2 1093.616058 547.8153 Mannosyl-oligosaccharide glucosidase OS=Homo sapiens OX=9606 GN=MOGS PE=1 SV=5 5.97 2984.4 - 213559 - - - 0.0988 - 1.307 0.291 - 185.1 1 2 0 0.0001 9 0 0 0 3.78E+07 1.20E+07 - - - 1.9649 0.9971 221125_WJC_METTL3_EV_vs_WT_F01.13676.13676.2 0.699 12-Jul K.ALVLQLK[136.11].E "sp|P46020|KPB1_HUMAN,tr|A6NMN0|A6NMN0_HUMAN,tr|A6NIT2|A6NIT2_HUMAN" 3 791.536 0.97 2686 13676 2 791.536428 396.7753 "Phosphorylase b kinase regulatory subunit alpha, skeletal muscle isoform OS=Homo sapiens OX=9606 GN=PHKA1 PE=1 SV=2" 8.8 2985.1 - 479106 - - - 0.5091 - 1.49 0.171 - 173 1 2 0 0.0004 7 0 0 0 3.56E+07 3.68E+07 - - - 1.5674 0.9984 221125_WJC_METTL3_EV_vs_WT_F01.13680.13680.2 0.0212 22-Jul K.SPILVATAVAAR[166.11].G "sp|O00571|DDX3X_HUMAN,sp|O15523|DDX3Y_HUMAN,tr|A0A2R8YFR4|A0A2R8YFR4_HUMAN,tr|A0A2R8YCW1|A0A2R8YCW1_HUMAN,tr|A0A2R8YDT5|A0A2R8YDT5_HUMAN,tr|A0A2R8Y645|A0A2R8Y645_HUMAN,tr|A0A2R8YF78|A0A2R8YF78_HUMAN,tr|A0A0D9SFB3|A0A0D9SFB3_HUMAN,tr|A0A2R8YFS5|A0A2R8YFS5_HUMAN,tr|A0A0D9SF53|A0A0D9SF53_HUMAN,tr|A0A087WVZ1|A0A087WVZ1_HUMAN,tr|A0A0J9YVQ7|A0A0J9YVQ7_HUMAN,tr|A0A2R8Y5G6|A0A2R8Y5G6_HUMAN,tr|A0A2R8Y7T2|A0A2R8Y7T2_HUMAN,tr|A0A0D9SG12|A0A0D9SG12_HUMAN,tr|F6S8Q4|F6S8Q4_HUMAN,tr|A0A2U3TZJ9|A0A2U3TZJ9_HUMAN,tr|A0A2R8Y4A4|A0A2R8Y4A4_HUMAN" 18 1177.7058 1.21 2688 13680 2 1177.706954 589.8602 ATP-dependent RNA helicase DDX3X OS=Homo sapiens OX=9606 GN=DDX3X PE=1 SV=3 9.47 2985.7 - 90605.7 - - - 0.9561 - 1.539 0.271 - 114.7 1 2 0 0.0011 12 0 0 0 4.26E+08 3.53E+08 - - - 2.1766 0.998 221125_WJC_METTL3_EV_vs_WT_F01.13682.13682.2 1.19 16-Sep K.LADMGIAIR.V sp|Q9Y3I0|RTCB_HUMAN 1 958.527 1.28 2690 13682 2 958.529151 480.2708 RNA-splicing ligase RtcB homolog OS=Homo sapiens OX=9606 GN=RTCB PE=1 SV=1 5.84 2985.9 - 1.01E+06 - - - 2.2576 - 1.88 0.243 - 222.6 1 2 0 0.0022 9 0 0 0 3.13E+08 2.44E+08 - - - 2.6614 0.9933 221125_WJC_METTL3_EV_vs_WT_F01.13702.13702.2 1.01 12-Jul K.ALVLQLK.E "sp|P46020|KPB1_HUMAN,tr|A6NMN0|A6NMN0_HUMAN,tr|A6NIT2|A6NIT2_HUMAN" 3 783.5218 0.97 2704 13702 2 783.522127 392.7682 "Phosphorylase b kinase regulatory subunit alpha, skeletal muscle isoform OS=Homo sapiens OX=9606 GN=PHKA1 PE=1 SV=2" 8.8 2988.3 - 1.07E+06 - - - 0.3854 - 1.408 0.11 - 177.6 1 2 0 0.0003 7 0 0 0 3.56E+07 3.68E+07 - - - 0.9376 0.9998 221125_WJC_METTL3_EV_vs_WT_F01.13704.13704.2 0.000409 13/22 K.SPILVATAVAAR.G "sp|O00571|DDX3X_HUMAN,sp|O15523|DDX3Y_HUMAN,tr|A0A2R8YFR4|A0A2R8YFR4_HUMAN,tr|A0A2R8YCW1|A0A2R8YCW1_HUMAN,tr|A0A2R8YDT5|A0A2R8YDT5_HUMAN,tr|A0A2R8Y645|A0A2R8Y645_HUMAN,tr|A0A2R8YF78|A0A2R8YF78_HUMAN,tr|A0A0D9SFB3|A0A0D9SFB3_HUMAN,tr|A0A2R8YFS5|A0A2R8YFS5_HUMAN,tr|A0A0D9SF53|A0A0D9SF53_HUMAN,tr|A0A087WVZ1|A0A087WVZ1_HUMAN,tr|A0A0J9YVQ7|A0A0J9YVQ7_HUMAN,tr|A0A2R8Y5G6|A0A2R8Y5G6_HUMAN,tr|A0A2R8Y7T2|A0A2R8Y7T2_HUMAN,tr|A0A0D9SG12|A0A0D9SG12_HUMAN,tr|F6S8Q4|F6S8Q4_HUMAN,tr|A0A2U3TZJ9|A0A2U3TZJ9_HUMAN,tr|A0A2R8Y4A4|A0A2R8Y4A4_HUMAN" 18 1167.6976 1.21 2706 13704 2 1167.69851 584.8561 ATP-dependent RNA helicase DDX3X OS=Homo sapiens OX=9606 GN=DDX3X PE=1 SV=3 9.47 2988.5 - 544393 - - - 0.8153 - 2.322 0.422 - 628.4 1 2 0 0.001 12 0 0 0 4.27E+08 3.53E+08 - - - 4.3742 0.9508 221125_WJC_METTL3_EV_vs_WT_F01.13705.13705.2 9.17 12-May R.MLETILR[166.11].M "sp|O75175|CNOT3_HUMAN,tr|B7Z6J7|B7Z6J7_HUMAN,tr|A0A2H2FJL5|A0A2H2FJL5_HUMAN,tr|A0A2R8Y7Z8|A0A2R8Y7Z8_HUMAN,tr|H7C3F5|H7C3F5_HUMAN,tr|A0A2R8Y6N5|A0A2R8Y6N5_HUMAN,tr|A0A0G2JNJ7|A0A0G2JNJ7_HUMAN,tr|H7C148|H7C148_HUMAN" 8 884.5029 2.4 2707 13705 2 884.502949 443.2587 CCR4-NOT transcription complex subunit 3 OS=Homo sapiens OX=9606 GN=CNOT3 PE=1 SV=1 5.75 2988.6 - 1.71E+06 - - - 0.0622 - 0.973 0.084 - 63.3 1 2 0 0.0001 7 0 0 0 9.08E+07 3.79E+07 - - - -0.4253 0.9981 221125_WJC_METTL3_EV_vs_WT_F01.13710.13710.2 0.0736 12-Jun K.LWNGLVK[136.11].V "sp|Q86SF2|GALT7_HUMAN,tr|H0YAH3|H0YAH3_HUMAN,tr|E9PBY3|E9PBY3_HUMAN" 3 836.5 1.25 2710 13710 2 836.501236 419.2573 N-acetylgalactosaminyltransferase 7 OS=Homo sapiens OX=9606 GN=GALNT7 PE=1 SV=1 8.75 2989.3 - 685731 - - - 1.5087 - 1.514 0.261 - 68.2 1 2 0 0.0013 7 0 0 0 1.09E+08 8.68E+07 - - - 2.2825 0.9987 221125_WJC_METTL3_EV_vs_WT_F01.13711.13711.2 0.0198 16-Jul K.VLPLEEAYR.F sp|Q9H223|EHD4_HUMAN 1 1088.5866 2.47 2711 13711 2 1088.58781 545.3006 EH domain-containing protein 4 OS=Homo sapiens OX=9606 GN=EHD4 PE=1 SV=1 4.53 2989.4 - 168141 - - - 1.1023 - 1.451 0.311 - 158 1 2 0 0.0012 9 0 0 0 2.59E+08 1.05E+08 - - - 2.4146 0.9888 221125_WJC_METTL3_EV_vs_WT_F01.13717.13717.2 1.83 12-Jul K.LWNGLVK.V "sp|Q86SF2|GALT7_HUMAN,tr|H0YAH3|H0YAH3_HUMAN,tr|E9PBY3|E9PBY3_HUMAN" 3 828.4858 1.25 2715 13717 2 828.487877 415.2502 N-acetylgalactosaminyltransferase 7 OS=Homo sapiens OX=9606 GN=GALNT7 PE=1 SV=1 8.75 2990.2 - 639008 - - - 2.5384 - 1.294 0.207 - 105.6 1 2 0 0.0021 7 0 0 0 1.08E+08 8.68E+07 - - - 1.3859 0.9997 221125_WJC_METTL3_EV_vs_WT_F01.13721.13721.2 0.00197 14-Aug K.VITMFVQR.Q "sp|P13010|XRCC5_HUMAN,tr|C9JZ81|C9JZ81_HUMAN,tr|H7C0H9|H7C0H9_HUMAN" 3 992.5477 2.47 2717 13721 2 992.548648 497.2811 X-ray repair cross-complementing protein 5 OS=Homo sapiens OX=9606 GN=XRCC5 PE=1 SV=3 9.72 2990.7 - 634346 - - - 0.933 - 1.789 0.393 - 212.4 1 2 0 0.0009 8 0 0 0 1.33E+08 5.37E+07 - - - 3.6977 0.9979 221125_WJC_METTL3_EV_vs_WT_F01.13724.13724.2 2.47 14-Nov K.LAVEAVLR[166.11].L "sp|P78371|TCPB_HUMAN,tr|F8VQ14|F8VQ14_HUMAN,tr|F5GWF6|F5GWF6_HUMAN" 3 879.5417 0.41 2718 13724 2 879.540886 440.7781 T-complex protein 1 subunit beta OS=Homo sapiens OX=9606 GN=CCT2 PE=1 SV=4 6 2991.1 - 4.98E+06 - - - -0.9505 - 1.822 0.137 - 605.4 1 2 0 -0.0008 8 0 0 0 2.31E+08 5.70E+08 - - - 1.862 0.7765 221125_WJC_METTL3_EV_vs_WT_F01.13732.13732.2 8.49 12-May R.AIILETR.Q "sp|P78423|X3CL1_HUMAN,tr|H3BSR6|H3BSR6_HUMAN,tr|J3QRA1|J3QRA1_HUMAN" 3 814.4913 18.59 2722 13732 2 814.493293 408.2529 Fractalkine OS=Homo sapiens OX=9606 GN=CX3CL1 PE=1 SV=1 6.05 2992.1 - 389799 - - - 2.5046 - 1.155 0.026 - 54.2 10 2 0 0.002 7 0 0 0 3.56E+07 1.92E+06 - - - -0.7577 0.8761 221125_WJC_METTL3_EV_vs_WT_F01.13733.13733.2 5.32 14-Jun K.YGIPLAYK[136.11].K "sp|Q96PY6|NEK1_HUMAN,tr|H0Y8M6|H0Y8M6_HUMAN" 2 931.5259 1.14 2723 13733 2 931.525015 466.7702 Serine\threonine-protein kinase Nek1 OS=Homo sapiens OX=9606 GN=NEK1 PE=1 SV=2 8.5 2992.2 - 141552 - - - -0.9007 - 0.898 0.044 - 69.3 1 2 0 -0.0008 8 0 0 0 5.76E+06 5.05E+06 - - - -0.9588 0.9957 221125_WJC_METTL3_EV_vs_WT_F01.13749.13749.2 0.282 12-Jul R.LWEAGWK[136.11].Q sp|Q9H0D6|XRN2_HUMAN 1 896.4636 0.91 2732 13749 2 896.463531 449.2391 5'-3' exoribonuclease 2 OS=Homo sapiens OX=9606 GN=XRN2 PE=1 SV=1 6 2994.3 - 3.52E+06 - - - -0.0636 - 1.421 0.142 - 159.2 1 2 0 -0.0001 7 0 0 0 2.52E+08 2.76E+08 - - - 1.2031 0.9843 221125_WJC_METTL3_EV_vs_WT_F01.13758.13758.2 0.118 14-Jul K.VLLSALER[166.11].L "sp|P11586|C1TC_HUMAN,tr|F5H2F4|F5H2F4_HUMAN,tr|V9GZ78|V9GZ78_HUMAN,tr|V9GYY3|V9GYY3_HUMAN,tr|A0A494C1T2|A0A494C1T2_HUMAN" 5 909.5523 1.51 2739 13758 2 909.54993 455.7834 "C-1-tetrahydrofolate synthase, cytoplasmic OS=Homo sapiens OX=9606 GN=MTHFD1 PE=1 SV=4" 5.97 2995.4 - 722395 - - - -2.5914 - 1.239 0.196 - 129.6 1 2 0 -0.0024 8 0 0 0 6.20E+08 4.12E+08 - - - 1.1342 0.9988 221125_WJC_METTL3_EV_vs_WT_F01.13761.13761.3 0.0572 Oct-48 R.LVHPGVAEVVFVK[136.11].K "sp|Q9BY77|PDIP3_HUMAN,tr|F6VRR5|F6VRR5_HUMAN" 2 1400.8271 2.43 2740 13761 3 1400.825322 467.9497 Polymerase delta-interacting protein 3 OS=Homo sapiens OX=9606 GN=POLDIP3 PE=1 SV=2 6.75 2995.7 - 314000 - - - -1.285 - 1.943 0.261 - 64.6 1 2 0 -0.0018 13 0 0 0 1.46E+07 6.01E+06 - - - 3.2503 0.9967 221125_WJC_METTL3_EV_vs_WT_F01.13763.13763.2 0.0179 16-Sep R.VLGVLEVSR[166.11].S "sp|Q9H0C8|ILKAP_HUMAN,tr|F8SNU7|F8SNU7_HUMAN,tr|H7C2I8|H7C2I8_HUMAN" 3 980.5894 1.22 2741 13763 2 980.587964 491.302 Integrin-linked kinase-associated serine\threonine phosphatase 2C OS=Homo sapiens OX=9606 GN=ILKAP PE=1 SV=1 5.97 2996 - 801310 - - - -1.4654 - 1.735 0.147 - 264 1 2 0 -0.0014 9 0 0 0 4.87E+07 3.97E+07 - - - 1.7204 0.9472 221125_WJC_METTL3_EV_vs_WT_F01.13764.13764.2 1.58 12-May K.IVQWDIR[166.11].S "sp|O60508|PRP17_HUMAN,tr|Q5SRN1|Q5SRN1_HUMAN" 2 938.5213 0.79 2742 13764 2 938.522917 470.2679 Pre-mRNA-processing factor 17 OS=Homo sapiens OX=9606 GN=CDC40 PE=1 SV=1 5.84 2996.1 - 266056 - - - 1.7005 - 1.096 0.082 - 73.1 1 2 0 0.0016 7 0 0 0 1.01E+07 1.27E+07 - - - -0.0634 0.9627 221125_WJC_METTL3_EV_vs_WT_F01.13769.13769.2 2.58 12-Jun K.EIMLGLK[136.11].R "sp|Q06210|GFPT1_HUMAN,tr|A0A6I8PRN4|A0A6I8PRN4_HUMAN,tr|A0A6I8PTT9|A0A6I8PTT9_HUMAN" 3 810.4765 0.85 2744 13769 2 810.474378 406.2455 Glutamine--fructose-6-phosphate aminotransferase [isomerizing] 1 OS=Homo sapiens OX=9606 GN=GFPT1 PE=1 SV=3 6.1 2996.7 - 2.31E+06 - - - -2.5701 - 1.323 0.079 - 131.3 1 2 0 -0.0021 7 0 0 0 1.39E+08 1.64E+08 - - - 0.5107 0.9935 221125_WJC_METTL3_EV_vs_WT_F01.13781.13781.2 0.216 14-Jul K.VLETFLAK[136.11].S "sp|Q14258|TRI25_HUMAN,tr|A0A3B3IUA7|A0A3B3IUA7_HUMAN" 2 927.5521 0.63 2753 13781 2 927.550834 464.7833 E3 ubiquitin\ISG15 ligase TRIM25 OS=Homo sapiens OX=9606 GN=TRIM25 PE=1 SV=2 5.97 2998 - 533212 - - - -1.3315 - 1.254 0.194 - 103.5 1 2 0 -0.0012 8 0 0 0 4.73E+07 7.56E+07 - - - 1.1561 0.9991 221125_WJC_METTL3_EV_vs_WT_F01.13782.13782.2 0.0867 16-Sep R.VLGVLEVSR.S "sp|Q9H0C8|ILKAP_HUMAN,tr|F8SNU7|F8SNU7_HUMAN,tr|H7C2I8|H7C2I8_HUMAN" 3 970.5811 0.42 2754 13782 2 970.581172 486.2978 Integrin-linked kinase-associated serine\threonine phosphatase 2C OS=Homo sapiens OX=9606 GN=ILKAP PE=1 SV=1 5.97 2998.1 - 808742 - - - 0.0422 - 1.682 0.261 - 168 1 2 0 0 9 0 0 0 1.63E+07 3.85E+07 - - - 2.4731 0.9859 221125_WJC_METTL3_EV_vs_WT_F01.13787.13787.2 0.684 12-Jun R.MLETILR.M "sp|O75175|CNOT3_HUMAN,tr|B7Z6J7|B7Z6J7_HUMAN,tr|A0A2H2FJL5|A0A2H2FJL5_HUMAN,tr|A0A2R8Y7Z8|A0A2R8Y7Z8_HUMAN,tr|H7C3F5|H7C3F5_HUMAN,tr|A0A2R8Y6N5|A0A2R8Y6N5_HUMAN,tr|A0A0G2JNJ7|A0A0G2JNJ7_HUMAN,tr|H7C148|H7C148_HUMAN" 8 874.4946 2.4 2756 13787 2 874.493154 438.2546 CCR4-NOT transcription complex subunit 3 OS=Homo sapiens OX=9606 GN=CNOT3 PE=1 SV=1 5.75 2998.7 - 633053 - - - -1.681 - 1.283 0.126 - 149.4 1 2 0 -0.0015 7 0 0 0 9.07E+07 3.77E+07 - - - 0.7608 0.9993 221125_WJC_METTL3_EV_vs_WT_F01.13794.13794.2 0.0369 14-Aug K.VLLSALER.L "sp|P11586|C1TC_HUMAN,tr|F5H2F4|F5H2F4_HUMAN,tr|V9GZ78|V9GZ78_HUMAN,tr|V9GYY3|V9GYY3_HUMAN,tr|A0A494C1T2|A0A494C1T2_HUMAN" 5 899.544 1.51 2759 13794 2 899.542811 450.7793 "C-1-tetrahydrofolate synthase, cytoplasmic OS=Homo sapiens OX=9606 GN=MTHFD1 PE=1 SV=4" 5.97 2999.7 - 9.07E+06 - - - -1.3407 - 1.69 0.33 - 270.3 1 2 0 -0.0012 8 0 0 0 6.20E+08 4.12E+08 - - - 3.0606 0.9998 221125_WJC_METTL3_EV_vs_WT_F01.13799.13799.2 2.45E-05 26-Sep K.IFVGGLSPDTPEEK[136.11].L "sp|Q14103|HNRPD_HUMAN,tr|H0Y8G5|H0Y8G5_HUMAN,tr|D6RF44|D6RF44_HUMAN,tr|D6RAF8|D6RAF8_HUMAN,tr|H0YA96|H0YA96_HUMAN" 5 1495.765 1.57 2762 13799 2 1495.766956 748.8898 Heterogeneous nuclear ribonucleoprotein D0 OS=Homo sapiens OX=9606 GN=HNRNPD PE=1 SV=1 4.14 3000.3 - 103683 - - - 1.3244 - 1.705 0.566 - 143.4 1 2 0 0.002 14 0 0 0 5.43E+06 3.45E+06 - - - 4.5598 0.999 221125_WJC_METTL3_EV_vs_WT_F01.13800.13800.2 0.000901 16-Aug K.LLVLDPAQR[166.11].L sp|P50750|CDK9_HUMAN 1 1033.616 0.7 2763 13800 2 1033.615517 517.8153 Cyclin-dependent kinase 9 OS=Homo sapiens OX=9606 GN=CDK9 PE=1 SV=3 5.84 3000.4 - 470464 - - - -0.4189 - 1.605 0.262 - 214.1 1 2 0 -0.0004 9 0 0 0 2.56E+07 3.68E+07 - - - 2.3448 0.9957 221125_WJC_METTL3_EV_vs_WT_F01.13819.13819.2 0.302 12-Jun K.LSAFAFK.Q sp|O75717|WDHD1_HUMAN 1 782.4327 0.62 2775 13819 2 782.43249 392.2236 WD repeat and HMG-box DNA-binding protein 1 OS=Homo sapiens OX=9606 GN=WDHD1 PE=1 SV=1 8.75 3002.7 - 399031 - - - -0.2377 - 1.402 0.148 - 76.8 1 2 0 -0.0002 7 0 0 0 1.13E+07 1.83E+07 - - - 1.2047 0.9763 221125_WJC_METTL3_EV_vs_WT_F01.13828.13828.2 0.0559 16-Jun R.EYQDLLNVK[136.11].M "sp|P08670|VIME_HUMAN,sp|P14136|GFAP_HUMAN,sp|P17661|DESM_HUMAN,sp|Q16352|AINX_HUMAN,sp|P07197|NFM_HUMAN,sp|P12036|NFH_HUMAN,sp|P07196|NFL_HUMAN,tr|A0A1W2PR46|A0A1W2PR46_HUMAN,tr|A0A1X7SBR3|A0A1X7SBR3_HUMAN,tr|K7EJU1|K7EJU1_HUMAN,tr|A0A1X7SCE1|A0A1X7SCE1_HUMAN,tr|A0A1W2PRT3|A0A1W2PRT3_HUMAN,tr|B0YJC5|B0YJC5_HUMAN,tr|B0YJC4|B0YJC4_HUMAN,tr|E7ESP9|E7ESP9_HUMAN,tr|E7EMV2|E7EMV2_HUMAN" 16 1128.5906 2.22 2780 13828 2 1128.588023 565.3026 Vimentin OS=Homo sapiens OX=9606 GN=VIM PE=1 SV=4 4.37 3003.8 - 212141 - - - -2.3188 - 1.116 0.182 - 132.4 1 2 0 -0.0026 9 0 0 0 1.22E+07 5.50E+06 - - - 0.7019 0.9993 221125_WJC_METTL3_EV_vs_WT_F01.13830.13830.2 0.0033 16-Aug K.VLPLEEAYR[166.11].F sp|Q9H223|EHD4_HUMAN 1 1098.5949 2.47 2781 13830 2 1098.594018 550.3047 EH domain-containing protein 4 OS=Homo sapiens OX=9606 GN=EHD4 PE=1 SV=1 4.53 3004 - 1.78E+06 - - - -0.7846 - 1.409 0.372 - 349.3 1 2 0 -0.0009 9 0 0 0 2.59E+08 1.05E+08 - - - 2.7803 0.9652 221125_WJC_METTL3_EV_vs_WT_F01.13833.13833.2 0.543 18-Jul K.LFTPSPEIVK.Y sp|Q8TCS8|PNPT1_HUMAN 1 1129.6383 1.12 2783 13833 2 1129.637028 565.8264 "Polyribonucleotide nucleotidyltransferase 1, mitochondrial OS=Homo sapiens OX=9606 GN=PNPT1 PE=1 SV=2" 6 3004.4 - 328128 - - - -1.1358 - 1.346 0.029 - 139.3 2 2 0 -0.0013 10 0 0 0 4.03E+06 3.60E+06 - - - -0.0503 0.9987 221125_WJC_METTL3_EV_vs_WT_F01.13863.13863.2 3.07 14-Sep K.LAVEAVLR.L "sp|P78371|TCPB_HUMAN,tr|F8VQ14|F8VQ14_HUMAN,tr|F5GWF6|F5GWF6_HUMAN" 3 869.5335 0.41 2804 13863 2 869.533244 435.774 T-complex protein 1 subunit beta OS=Homo sapiens OX=9606 GN=CCT2 PE=1 SV=4 6 3008.1 - 1.56E+06 - - - -0.2392 - 1.829 0.176 - 267 1 2 0 -0.0002 8 0 0 0 2.32E+08 5.71E+08 - - - 2.1618 0.9966 221125_WJC_METTL3_EV_vs_WT_F01.13865.13865.2 0.148 12-Jul R.VVEFLVK[136.11].H sp|P42773|CDN2C_HUMAN 1 840.52 1.97 2805 13865 2 840.52087 421.2673 Cyclin-dependent kinase 4 inhibitor C OS=Homo sapiens OX=9606 GN=CDKN2C PE=1 SV=1 5.97 3008.3 - 740706 - - - 0.9863 - 1.466 0.181 - 150.8 1 2 0 0.0008 7 0 0 0 6.35E+07 3.22E+07 - - - 1.5897 0.9986 221125_WJC_METTL3_EV_vs_WT_F01.13866.13866.2 0.205 16-Oct R.LAEYYGLYR[166.11].D sp|Q96DV4|RM38_HUMAN 1 1156.5792 1.26 2806 13866 2 1156.580065 579.2969 "39S ribosomal protein L38, mitochondrial OS=Homo sapiens OX=9606 GN=MRPL38 PE=1 SV=2" 6 3008.4 - 537142 - - - 0.722 - 1.832 0.193 - 462.9 1 2 0 0.0008 9 0 0 0 4.43E+07 3.51E+07 - - - 2.2177 0.9997 221125_WJC_METTL3_EV_vs_WT_F01.13882.13882.2 0.187 18-Nov R.VPLVAPEDLR.D "sp|O14744|ANM5_HUMAN,tr|C9JSX3|C9JSX3_HUMAN,tr|G3V580|G3V580_HUMAN,tr|G3V2X6|G3V2X6_HUMAN,tr|G3V5L5|G3V5L5_HUMAN,tr|H0YJX6|H0YJX6_HUMAN" 6 1107.6288 3.1 2816 13882 2 1107.629447 554.8217 Protein arginine N-methyltransferase 5 OS=Homo sapiens OX=9606 GN=PRMT5 PE=1 SV=4 4.37 3010.5 - 769770 - - - 0.576 - 2.226 0.305 - 547.9 1 2 0 0.0006 10 0 0 0 3.08E+09 9.91E+08 - - - 3.5271 0.9996 221125_WJC_METTL3_EV_vs_WT_F01.13896.13896.2 0.0306 16-Sep K.LNSLAIGLR.Q sp|P54886|P5CS_HUMAN 1 955.5815 0.75 2825 13896 2 955.581292 478.798 Delta-1-pyrroline-5-carboxylate synthase OS=Homo sapiens OX=9606 GN=ALDH18A1 PE=1 SV=2 9.75 3012.2 - 1.36E+06 - - - -0.181 - 1.84 0.35 - 228.8 1 2 0 -0.0002 9 0 0 0 3.51E+07 4.70E+07 - - - 3.3901 0.9995 221125_WJC_METTL3_EV_vs_WT_F01.13899.13899.2 0.0439 16-Aug R.AYALAFAER[166.11].G "sp|P51659|DHB4_HUMAN,tr|A0A2R8YD50|A0A2R8YD50_HUMAN,tr|A0A804HLJ0|A0A804HLJ0_HUMAN,tr|A0A804HIR1|A0A804HIR1_HUMAN,tr|E7ER27|E7ER27_HUMAN,tr|A0A2R8YF45|A0A2R8YF45_HUMAN,tr|E7EPL9|E7EPL9_HUMAN,tr|A0A804HKU2|A0A804HKU2_HUMAN,tr|A0A804HKT2|A0A804HKT2_HUMAN,tr|A0A2R8YDT8|A0A2R8YDT8_HUMAN,tr|A0A804HK65|A0A804HK65_HUMAN,tr|A0A2R8YEG2|A0A2R8YEG2_HUMAN" 12 1020.5268 0.75 2827 13899 2 1020.525776 511.2707 Peroxisomal multifunctional enzyme type 2 OS=Homo sapiens OX=9606 GN=HSD17B4 PE=1 SV=3 6.05 3012.6 - 543868 - - - -1.0044 - 1.85 0.319 - 285.1 1 2 0 -0.001 9 0 0 0 2.46E+07 3.29E+07 - - - 3.1766 0.9659 221125_WJC_METTL3_EV_vs_WT_F01.13901.13901.2 9.21 12-Jun R.MLFVTPR.R "sp|Q9P2N6|KANL3_HUMAN,tr|C9J491|C9J491_HUMAN,tr|M0R3B6|M0R3B6_HUMAN,tr|A0A590UJ53|A0A590UJ53_HUMAN,tr|F8WB58|F8WB58_HUMAN,tr|F8WEN2|F8WEN2_HUMAN,tr|F8WD76|F8WD76_HUMAN" 7 862.4735 0.19 2829 13901 2 862.472937 432.244 KAT8 regulatory NSL complex subunit 3 OS=Homo sapiens OX=9606 GN=KANSL3 PE=1 SV=2 9.5 3012.8 - 609696 - - - -0.647 - 1.138 0.054 - 119.8 1 2 0 -0.0006 7 0 0 0 2.69E+07 1.39E+08 - - - -0.1507 0.9991 221125_WJC_METTL3_EV_vs_WT_F01.13904.13904.2 0.0151 18-Aug K.IMLVEPPVAK[136.11].V sp|P18583|SON_HUMAN 1 1103.6504 1.69 2830 13904 2 1103.650081 552.8325 Protein SON OS=Homo sapiens OX=9606 GN=SON PE=1 SV=4 6 3013.2 - 329370 - - - -0.2918 - 1.659 0.267 - 187.7 1 2 0 -0.0003 10 0 0 0 1.78E+08 1.06E+08 - - - 2.426 0.9979 221125_WJC_METTL3_EV_vs_WT_F01.13907.13907.2 0.0565 14-Oct K.VPGIFISR[166.11].M "sp|Q9BYG4|PAR6G_HUMAN,sp|Q9NPB6|PAR6A_HUMAN,sp|Q9BYG5|PAR6B_HUMAN,tr|R4GMM2|R4GMM2_HUMAN" 4 897.5312 0.02 2833 13907 2 897.531129 449.7729 Partitioning defective 6 homolog gamma OS=Homo sapiens OX=9606 GN=PARD6G PE=1 SV=1 9.72 3013.4 - 1.44E+06 - - - -0.0323 - 1.859 0.116 - 301.3 1 2 0 0 8 0 0 0 1.28E+07 5.64E+08 - - - 1.7678 0.9989 221125_WJC_METTL3_EV_vs_WT_F01.13910.13910.2 0.0213 12-Aug R.FLDPEFR.E sp|Q5VUA4|ZN318_HUMAN 1 922.4549 1.67 2835 13910 2 922.453859 462.2347 Zinc finger protein 318 OS=Homo sapiens OX=9606 GN=ZNF318 PE=1 SV=2 4.37 3013.8 - 1.47E+06 - - - -1.0938 - 1.49 0.29 - 229.9 1 2 0 -0.001 7 0 0 0 4.63E+07 2.78E+07 - - - 2.4462 0.9996 221125_WJC_METTL3_EV_vs_WT_F01.13914.13914.2 0.00285 18-Dec R.IATANMLGIR[166.11].K sp|Q9NX20|RM16_HUMAN 1 1068.5989 0.11 2839 13914 2 1068.598946 535.3067 "39S ribosomal protein L16, mitochondrial OS=Homo sapiens OX=9606 GN=MRPL16 PE=1 SV=1" 9.75 3014.3 - 528483 - - - 0.0243 - 2.129 0.298 - 495.5 1 2 0 0 10 0 0 0 3.41E+06 3.00E+07 - - - 3.3513 0.9998 221125_WJC_METTL3_EV_vs_WT_F01.13916.13916.2 0.00572 16-Oct K.LNSLAIGLR[166.11].Q sp|P54886|P5CS_HUMAN 1 965.5897 0.74 2840 13916 2 965.58936 483.8021 Delta-1-pyrroline-5-carboxylate synthase OS=Homo sapiens OX=9606 GN=ALDH18A1 PE=1 SV=2 9.75 3014.5 - 1.68E+06 - - - -0.3884 - 2.274 0.335 - 349.2 1 2 0 -0.0004 9 0 0 0 3.52E+07 4.75E+07 - - - 3.892 0.9997 221125_WJC_METTL3_EV_vs_WT_F01.13918.13918.2 0.00051 18-Sep K.IMLVEPPVAK.V sp|P18583|SON_HUMAN 1 1095.6362 1.87 2841 13918 2 1095.636285 548.8254 Protein SON OS=Homo sapiens OX=9606 GN=SON PE=1 SV=4 6 3014.7 - 624013 - - - 0.0748 - 1.852 0.398 - 306.6 1 2 0 0.0001 10 0 0 0 2.64E+07 1.41E+07 - - - 3.7008 0.9998 221125_WJC_METTL3_EV_vs_WT_F01.13919.13919.2 2.19E-05 16-Oct K.MYLQAAIVR[166.11].L "sp|Q13617|CUL2_HUMAN,tr|A0A0A0MTN0|A0A0A0MTN0_HUMAN" 2 1073.5931 0.55 2842 13919 2 1073.592877 537.8038 Cullin-2 OS=Homo sapiens OX=9606 GN=CUL2 PE=1 SV=2 8.5 3014.8 - 495782 - - - -0.2133 - 2.034 0.449 - 357.4 1 2 0 -0.0002 9 0 0 0 4.91E+06 8.89E+06 - - - 4.4113 0.9679 221125_WJC_METTL3_EV_vs_WT_F01.13922.13922.2 0.727 12-Jul K.TLPIAFK.V "sp|Q01196|RUNX1_HUMAN,tr|A8MZI9|A8MZI9_HUMAN,tr|C9JWM1|C9JWM1_HUMAN,tr|H9KVB1|H9KVB1_HUMAN" 4 788.4796 0.42 2845 13922 2 788.478799 395.2471 Runt-related transcription factor 1 OS=Homo sapiens OX=9606 GN=RUNX1 PE=1 SV=3 8.41 3015.1 - 439293 - - - -1.0489 - 1.239 0.035 - 176.3 1 2 0 -0.0008 7 0 0 0 1.05E+07 2.51E+07 - - - -0.0217 0.9965 221125_WJC_METTL3_EV_vs_WT_F01.13930.13930.2 0.0878 18-Sep K.LPAVVTADLR[166.11].L "sp|P38117|ETFB_HUMAN,tr|M0QY67|M0QY67_HUMAN" 2 1063.6265 1.65 2851 13930 2 1063.623303 532.8205 Electron transfer flavoprotein subunit beta OS=Homo sapiens OX=9606 GN=ETFB PE=1 SV=3 5.84 3016.1 - 396444 - - - -3.0199 - 1.675 0.287 - 254 1 2 0 -0.0032 10 0 0 0 1.81E+08 1.10E+08 - - - 2.5996 0.9992 221125_WJC_METTL3_EV_vs_WT_F01.13936.13936.2 0.0111 28-Jun R.GALQNIIPASTGAAK[136.11].A "sp|P04406|G3P_HUMAN,tr|E7EUT5|E7EUT5_HUMAN" 2 1418.7973 1.29 2855 13936 2 1418.796273 710.4059 Glyceraldehyde-3-phosphate dehydrogenase OS=Homo sapiens OX=9606 GN=GAPDH PE=1 SV=3 8.75 3016.9 - 145608 - - - -0.7083 - 1.43 0.375 - 42.8 1 2 0 -0.001 15 0 0 0 2.01E+07 1.56E+07 - - - 2.6898 0.9989 221125_WJC_METTL3_EV_vs_WT_F01.13941.13941.2 0.0329 14-Jul K.LITEDFVR.Q sp|Q96MG7|NSE3_HUMAN 1 991.5338 11.72 2858 13941 2 991.532322 496.7742 Non-structural maintenance of chromosomes element 3 homolog OS=Homo sapiens OX=9606 GN=NSMCE3 PE=1 SV=1 4.37 3017.6 - 580119 - - - -1.537 - 1.545 0.32 - 129.7 1 2 0 -0.0015 8 0 0 0 1.26E+07 1.07E+06 - - - 2.7161 0.8889 221125_WJC_METTL3_EV_vs_WT_F01.13942.13942.2 2.12 16-Oct R.AGVIFPVGR[166.11].L "sp|Q9P0M6|H2AW_HUMAN,sp|O75367|H2AY_HUMAN,tr|A0A7I2YQD6|A0A7I2YQD6_HUMAN,tr|B4DJC3|B4DJC3_HUMAN,tr|A0A7I2V412|A0A7I2V412_HUMAN,tr|Q5SQT3|Q5SQT3_HUMAN,tr|A0A7I2V423|A0A7I2V423_HUMAN,tr|A0A7I2V2N7|A0A7I2V2N7_HUMAN,tr|A0A7I2V4D9|A0A7I2V4D9_HUMAN,tr|D6RCF2|D6RCF2_HUMAN,tr|A0A7I2V6E9|A0A7I2V6E9_HUMAN,tr|A0A7I2YQB9|A0A7I2YQB9_HUMAN,tr|A0A7I2YQR8|A0A7I2YQR8_HUMAN" 13 924.5421 0.59 2859 13942 2 924.546236 463.2783 Core histone macro-H2A.2 OS=Homo sapiens OX=9606 GN=MACROH2A2 PE=1 SV=3 9.79 3017.7 - 543597 - - - 4.5201 - 1.442 0.082 - 333.2 1 2 0 0.0042 9 0 0 0 3.28E+07 5.55E+07 - - - 0.7043 0.9993 221125_WJC_METTL3_EV_vs_WT_F01.13947.13947.2 0.00038 28-Aug R.GALQNIIPASTGAAK.A "sp|P04406|G3P_HUMAN,tr|E7EUT5|E7EUT5_HUMAN" 2 1410.7831 1.32 2862 13947 2 1410.780976 706.3988 Glyceraldehyde-3-phosphate dehydrogenase OS=Homo sapiens OX=9606 GN=GAPDH PE=1 SV=3 8.75 3018.3 - 234874 - - - -1.49 - 1.731 0.38 - 101.3 1 2 0 -0.0021 15 0 0 0 1.98E+07 1.50E+07 - - - 3.196 0.9516 221125_WJC_METTL3_EV_vs_WT_F01.13950.13950.2 0.0227 12-Aug A.KELAEER[166.11].M sp|Q7RTP6|MICA3_HUMAN 1 883.4639 - 2863 13950 2 883.462781 442.7392 [F-actin]-monooxygenase MICAL3 OS=Homo sapiens OX=9606 GN=MICAL3 PE=1 SV=2 4.79 3018.7 - 2.34E+06 - - - -1.2281 - 1.822 0.25 - 329.4 1 1 0 -0.0011 7 0 0 0 - - - - - 2.7881 0.9942 221125_WJC_METTL3_EV_vs_WT_F01.13953.13953.2 0.627 16-Jul R.IMDPEIALK.L sp|Q9H0L4|CSTFT_HUMAN 1 1028.5576 3.04 2866 13953 2 1028.556894 515.2861 Cleavage stimulation factor subunit 2 tau variant OS=Homo sapiens OX=9606 GN=CSTF2T PE=1 SV=1 4.37 3019.1 - 307657 - - - -0.7039 - 1.307 0.167 - 93.9 1 2 0 -0.0007 9 0 0 0 1.30E+07 4.26E+06 - - - 1.0488 0.991 221125_WJC_METTL3_EV_vs_WT_F01.13957.13957.2 0.304 14-Aug K.VPGIFISR.M "sp|Q9BYG4|PAR6G_HUMAN,sp|Q9NPB6|PAR6A_HUMAN,sp|Q9BYG5|PAR6B_HUMAN,tr|R4GMM2|R4GMM2_HUMAN" 4 887.5229 0.12 2869 13957 2 887.522501 444.7687 Partitioning defective 6 homolog gamma OS=Homo sapiens OX=9606 GN=PARD6G PE=1 SV=1 9.72 3019.6 - 2.84E+06 - - - -0.436 - 1.398 0.088 - 189.8 1 2 0 -0.0004 8 0 0 0 6.86E+07 5.90E+08 - - - 0.7013 0.9911 221125_WJC_METTL3_EV_vs_WT_F01.13959.13959.2 11.8 12-Aug K.IGIEIIK.R "sp|P10809|CH60_HUMAN,tr|A0A7I2V2X6|A0A7I2V2X6_HUMAN,tr|A0A7I2YQK6|A0A7I2YQK6_HUMAN,tr|A0A7I2V599|A0A7I2V599_HUMAN" 4 784.5058 1.27 2870 13959 2 784.505396 393.2602 "60 kDa heat shock protein, mitochondrial OS=Homo sapiens OX=9606 GN=HSPD1 PE=1 SV=2" 6 3019.8 - 6.69E+06 - - - -0.5672 - 1.77 0.001 - 133.6 2 2 0 -0.0004 7 0 0 0 2.51E+10 1.97E+10 - - - 0.723 0.9009 221125_WJC_METTL3_EV_vs_WT_F01.13960.13960.2 0.165 14-Aug M.PTPVILLK[136.11].E "sp|Q99832|TCPH_HUMAN,tr|A0A0D9SG95|A0A0D9SG95_HUMAN,tr|F8WBP8|F8WBP8_HUMAN" 3 887.5935 0.15 2871 13960 2 887.593052 444.804 T-complex protein 1 subunit eta OS=Homo sapiens OX=9606 GN=CCT7 PE=1 SV=2 9.18 3019.8 - 2.92E+06 - - - -0.5498 - 1.362 0.26 - 171.3 1 1 0 -0.0005 8 0 0 0 1.07E+07 7.19E+07 - - - 1.893 0.999 221125_WJC_METTL3_EV_vs_WT_F01.13962.13962.2 0.0519 16-Sep R.VLQALEGLK[136.11].M "sp|P39019|RS19_HUMAN,tr|A0A075B6E2|A0A075B6E2_HUMAN" 2 977.6001 1.16 2873 13962 2 977.598568 489.8073 40S ribosomal protein S19 OS=Homo sapiens OX=9606 GN=RPS19 PE=1 SV=2 5.97 3020 - 1.67E+06 - - - -1.5487 - 1.706 0.301 - 216.6 1 2 0 -0.0015 9 0 0 0 6.82E+08 5.90E+08 - - - 2.809 0.9994 221125_WJC_METTL3_EV_vs_WT_F01.13965.13965.2 0.000823 16-Aug R.FLAEEGFYK[136.11].F "sp|P46977|STT3A_HUMAN,tr|A0A0C4DH80|A0A0C4DH80_HUMAN,tr|E9PN73|E9PN73_HUMAN,tr|E9PI32|E9PI32_HUMAN" 4 1110.5477 1.18 2876 13965 2 1110.547923 556.2811 Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit STT3A OS=Homo sapiens OX=9606 GN=STT3A PE=1 SV=2 4.53 3020.3 - 375305 - - - 0.19 - 1.472 0.375 - 150.5 1 2 0 0.0002 9 0 0 0 1.16E+08 9.84E+07 - - - 2.9292 0.9996 221125_WJC_METTL3_EV_vs_WT_F01.13970.13970.2 0.00215 16-Oct R.VLAGLYMGR[166.11].S sp|Q92616|GCN1_HUMAN 1 988.5403 0.59 2879 13970 2 988.539442 495.2774 eIF-2-alpha kinase activator GCN1 OS=Homo sapiens OX=9606 GN=GCN1 PE=1 SV=6 8.72 3021 - 575761 - - - -0.9104 - 1.705 0.37 - 255.1 1 2 0 -0.0009 9 0 0 0 1.34E+07 2.27E+07 - - - 3.3172 0.9995 221125_WJC_METTL3_EV_vs_WT_F01.13976.13976.2 0.0063 12-Sep R.IAAYLFK[136.11].G "sp|Q00610|CLH1_HUMAN,tr|K7EJJ5|K7EJJ5_HUMAN,tr|J3KS13|J3KS13_HUMAN,tr|A0A087WVQ6|A0A087WVQ6_HUMAN,tr|J3KRF5|J3KRF5_HUMAN" 5 832.4938 0.91 2883 13976 2 832.492885 417.2542 Clathrin heavy chain 1 OS=Homo sapiens OX=9606 GN=CLTC PE=1 SV=5 8.59 3021.8 - 7.02E+06 - - - -1.1303 - 1.84 0.324 - 238.5 1 2 0 -0.0009 7 0 0 0 1.44E+08 1.58E+08 - - - 3.3658 0.9998 221125_WJC_METTL3_EV_vs_WT_F01.13978.13978.2 0.00927 16-Oct R.FLAEEGFYK.F "sp|P46977|STT3A_HUMAN,tr|A0A0C4DH80|A0A0C4DH80_HUMAN,tr|E9PN73|E9PN73_HUMAN,tr|E9PI32|E9PI32_HUMAN" 4 1102.5335 1.18 2885 13978 2 1102.532758 552.274 Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit STT3A OS=Homo sapiens OX=9606 GN=STT3A PE=1 SV=2 4.53 3021.9 - 1.16E+06 - - - -0.6839 - 1.659 0.48 - 254.3 1 2 0 -0.0008 9 0 0 0 1.16E+08 9.84E+07 - - - 4.0506 0.9986 221125_WJC_METTL3_EV_vs_WT_F01.13979.13979.2 0.113 12-Jun R.FWETLDR.Y "sp|Q6P1J9|CDC73_HUMAN,tr|A0A1B0GUB2|A0A1B0GUB2_HUMAN" 2 965.4607 1.22 2886 13979 2 965.45952 483.7376 Parafibromin OS=Homo sapiens OX=9606 GN=CDC73 PE=1 SV=1 4.37 3022.1 - 931518 - - - -1.2025 - 1.356 0.316 - 134.1 1 2 0 -0.0012 7 0 0 0 4.41E+07 3.62E+07 - - - 2.3396 0.9965 221125_WJC_METTL3_EV_vs_WT_F01.13985.13985.2 0.162 14-Jun R.IGFIEEVK.A sp|Q96P63|SPB12_HUMAN 1 933.5171 15.33 2891 13985 2 933.516659 467.7658 Serpin B12 OS=Homo sapiens OX=9606 GN=SERPINB12 PE=1 SV=1 4.53 3022.8 - 7.50E+06 - - - -0.5088 - 1.288 0.214 - 83.1 1 2 0 -0.0005 8 0 0 0 4.18E+08 2.73E+07 - - - 1.3848 0.9983 221125_WJC_METTL3_EV_vs_WT_F01.13987.13987.2 0.47 12-Aug R.IAAYLFK.G "sp|Q00610|CLH1_HUMAN,tr|K7EJJ5|K7EJJ5_HUMAN,tr|J3KS13|J3KS13_HUMAN,tr|A0A087WVQ6|A0A087WVQ6_HUMAN,tr|J3KRF5|J3KRF5_HUMAN" 5 824.4796 0.91 2892 13987 2 824.478885 413.2471 Clathrin heavy chain 1 OS=Homo sapiens OX=9606 GN=CLTC PE=1 SV=5 8.59 3023 - 5.98E+06 - - - -0.8987 - 1.61 0.2 - 172 1 2 0 -0.0007 7 0 0 0 1.44E+08 1.58E+08 - - - 2.0269 0.9906 221125_WJC_METTL3_EV_vs_WT_F01.13991.13991.2 0.00899 18-Aug K.WTLLQEQGTK.T "sp|P48668|K2C6C_HUMAN,sp|P04259|K2C6B_HUMAN,sp|P13647|K2C5_HUMAN,sp|P02538|K2C6A_HUMAN,tr|F8W0C6|F8W0C6_HUMAN" 5 1202.6295 128.92 2896 13991 2 1202.63092 602.322 "Keratin, type II cytoskeletal 6C OS=Homo sapiens OX=9606 GN=KRT6C PE=1 SV=3" 6 3023.5 - 393073 - - - 1.1491 - 1.638 0.066 - 152.2 1 2 0 0.0014 10 0 0 0 3.30E+07 2.56E+05 - - - 0.9055 0.9985 221125_WJC_METTL3_EV_vs_WT_F01.13992.13992.2 0.0057 20-Jul K.LIPGPLSPVAR.G sp|P48634|PRC2A_HUMAN 1 1118.6812 1.07 2897 13992 2 1118.679862 560.3479 Protein PRRC2A OS=Homo sapiens OX=9606 GN=PRRC2A PE=1 SV=3 9.75 3023.6 - 336728 - - - -1.1773 - 1.542 0.278 - 125.5 1 2 0 -0.0013 11 0 0 0 4.37E+08 4.10E+08 - - - 2.2655 0.9993 221125_WJC_METTL3_EV_vs_WT_F01.13998.13998.2 0.653 18-Oct K.LPAVVTADLR.L "sp|P38117|ETFB_HUMAN,tr|M0QY67|M0QY67_HUMAN" 2 1053.6182 1.58 2901 13998 2 1053.616758 527.8164 Electron transfer flavoprotein subunit beta OS=Homo sapiens OX=9606 GN=ETFB PE=1 SV=3 5.84 3024.4 - 1.33E+06 - - - -1.4113 - 2.105 0.263 - 424.9 1 2 0 -0.0015 10 0 0 0 1.85E+08 1.17E+08 - - - 3.0607 0.9799 221125_WJC_METTL3_EV_vs_WT_F01.14004.14004.2 1.49 14-Jul K.ALLSDMVR[166.11].S "sp|O14776|TCRG1_HUMAN,tr|A0A7P0T8N8|A0A7P0T8N8_HUMAN,tr|G3V220|G3V220_HUMAN" 3 913.4931 1.12 2904 14004 2 913.491236 457.7538 Transcription elongation regulator 1 OS=Homo sapiens OX=9606 GN=TCERG1 PE=1 SV=2 5.88 3025.2 - 1.06E+06 - - - -1.9945 - 1.244 0.13 - 113.8 1 2 0 -0.0018 8 0 0 0 7.94E+07 7.12E+07 - - - 0.6591 0.9986 221125_WJC_METTL3_EV_vs_WT_F01.14005.14005.2 0.0685 20-Jul K.LIPGPLSPVAR[166.11].G sp|P48634|PRC2A_HUMAN 1 1128.6894 1.07 2905 14005 2 1128.687579 565.352 Protein PRRC2A OS=Homo sapiens OX=9606 GN=PRRC2A PE=1 SV=3 9.75 3025.3 - 1.14E+06 - - - -1.6568 - 1.609 0.305 - 142.4 1 2 0 -0.0019 11 0 0 0 4.39E+08 4.10E+08 - - - 2.5798 0.8803 221125_WJC_METTL3_EV_vs_WT_F01.14014.14014.2 3.96 14-Jul R.LPEDVLLK[136.11].E "sp|Q92696|PGTA_HUMAN,tr|H0YLH3|H0YLH3_HUMAN" 2 933.5626 1.24 2912 14014 2 933.560362 467.7886 Geranylgeranyl transferase type-2 subunit alpha OS=Homo sapiens OX=9606 GN=RABGGTA PE=1 SV=2 4.37 3026.2 - 1.37E+06 - - - -2.4337 - 0.938 0.108 - 101 1 2 0 -0.0023 8 0 0 0 7.09E+07 5.74E+07 - - - -0.3551 0.9995 221125_WJC_METTL3_EV_vs_WT_F01.14017.14017.2 0.104 16-Oct R.GSPLLIGVR[166.11].S "sp|Q06210|GFPT1_HUMAN,sp|O94808|GFPT2_HUMAN,tr|A0A6I8PRN4|A0A6I8PRN4_HUMAN,tr|E5RJP4|E5RJP4_HUMAN,tr|A0A6I8PTT9|A0A6I8PTT9_HUMAN" 5 920.5683 1.04 2913 14017 2 920.566473 461.2914 Glutamine--fructose-6-phosphate aminotransferase [isomerizing] 1 OS=Homo sapiens OX=9606 GN=GFPT1 PE=1 SV=3 9.75 3026.6 - 2.03E+06 - - - -1.9542 - 2.051 0.357 - 400 1 2 0 -0.0018 9 0 0 0 2.52E+08 2.42E+08 - - - 3.7554 0.9978 221125_WJC_METTL3_EV_vs_WT_F01.14021.14021.2 0.00591 16-Sep R.GSPLLIGVR.S "sp|Q06210|GFPT1_HUMAN,sp|O94808|GFPT2_HUMAN,tr|A0A6I8PRN4|A0A6I8PRN4_HUMAN,tr|E5RJP4|E5RJP4_HUMAN,tr|A0A6I8PTT9|A0A6I8PTT9_HUMAN" 5 910.56 1.05 2914 14021 2 910.556662 456.2873 Glutamine--fructose-6-phosphate aminotransferase [isomerizing] 1 OS=Homo sapiens OX=9606 GN=GFPT1 PE=1 SV=3 9.75 3027.1 - 1.63E+06 - - - -3.6681 - 1.678 0.409 - 244.7 1 2 0 -0.0033 9 0 0 0 2.52E+08 2.41E+08 - - - 3.5583 0.9969 221125_WJC_METTL3_EV_vs_WT_F01.14033.14033.2 0.0645 16-Sep R.VLQALEGLK.M "sp|P39019|RS19_HUMAN,tr|A0A075B6E2|A0A075B6E2_HUMAN" 2 969.5859 1.16 2922 14033 2 969.582943 485.8002 40S ribosomal protein S19 OS=Homo sapiens OX=9606 GN=RPS19 PE=1 SV=2 5.97 3028.5 - 2.32E+07 - - - -3.0312 - 1.81 0.268 - 275.5 1 2 0 -0.0029 9 0 0 0 6.82E+08 5.90E+08 - - - 2.7361 0.9303 221125_WJC_METTL3_EV_vs_WT_F01.14035.14035.2 5.01 14-Aug K.ALLSDMVR.S "sp|O14776|TCRG1_HUMAN,tr|A0A7P0T8N8|A0A7P0T8N8_HUMAN,tr|G3V220|G3V220_HUMAN" 3 903.4848 1.12 2923 14035 2 903.482117 452.7497 Transcription elongation regulator 1 OS=Homo sapiens OX=9606 GN=TCERG1 PE=1 SV=2 5.88 3028.7 - 1.45E+06 - - - -2.9563 - 1.306 0.057 - 209.1 1 2 0 -0.0027 8 0 0 0 7.98E+07 7.13E+07 - - - 0.2663 0.9991 221125_WJC_METTL3_EV_vs_WT_F01.14036.14036.2 0.00127 20-Nov K.ILATTPSAVFR.V "sp|Q9NRG9|AAAS_HUMAN,tr|H3BU82|H3BU82_HUMAN,tr|F8VZ44|F8VZ44_HUMAN" 3 1174.671 1.4 2924 14036 2 1174.66792 588.3428 Aladin OS=Homo sapiens OX=9606 GN=AAAS PE=1 SV=1 9.75 3028.9 - 1.09E+06 - - - -2.6297 - 1.919 0.39 - 338.4 1 2 0 -0.0031 11 0 0 0 7.94E+07 5.66E+07 - - - 3.6839 0.9976 221125_WJC_METTL3_EV_vs_WT_F01.14037.14037.2 0.0044 20-Oct K.ILATTPSAVFR[166.11].V "sp|Q9NRG9|AAAS_HUMAN,tr|H3BU82|H3BU82_HUMAN,tr|F8VZ44|F8VZ44_HUMAN" 3 1184.6793 1.4 2925 14037 2 1184.674905 593.3469 Aladin OS=Homo sapiens OX=9606 GN=AAAS PE=1 SV=1 9.75 3029 - 687336 - - - -3.6921 - 1.871 0.375 - 260.9 1 2 0 -0.0044 11 0 0 0 7.94E+07 5.66E+07 - - - 3.5041 0.8872 221125_WJC_METTL3_EV_vs_WT_F01.14042.14042.2 9.97 12-May K.QLQEAHR[166.11].D "sp|P46939|UTRN_HUMAN,tr|Q5T097|Q5T097_HUMAN" 2 890.4598 1.25 2928 14042 2 890.460243 446.2372 Utrophin OS=Homo sapiens OX=9606 GN=UTRN PE=1 SV=2 6.75 3029.6 - 3.50E+06 - - - 0.5155 - 1.026 0.012 - 72.3 2 2 0 0.0005 7 0 0 0 1.10E+08 8.81E+07 - - - -0.9237 0.9981 221125_WJC_METTL3_EV_vs_WT_F01.14047.14047.2 0.035 16-Oct K.TLAIELAPR[166.11].N "sp|P0CG22|DR4L1_HUMAN,sp|Q6PKH6|DR4L2_HUMAN,sp|Q9BTZ2|DHRS4_HUMAN,tr|A0A087WSZ6|A0A087WSZ6_HUMAN,tr|F6TD35|F6TD35_HUMAN,tr|F6VUV4|F6VUV4_HUMAN,tr|A0A087WXI8|A0A087WXI8_HUMAN,tr|H0YKN3|H0YKN3_HUMAN" 8 992.5894 1.47 2930 14047 2 992.585698 497.302 Putative dehydrogenase\reductase SDR family member 4-like 1 OS=Homo sapiens OX=9606 GN=DHRS4L1 PE=5 SV=1 5.66 3030.2 - 937361 - - - -3.7306 - 1.928 0.388 - 411.9 1 2 0 -0.0037 9 0 0 0 7.97E+08 5.43E+08 - - - 3.8048 0.9892 221125_WJC_METTL3_EV_vs_WT_F01.14057.14057.2 0.0494 14-Jun K.FVADGIFK.A "sp|P23396|RS3_HUMAN,tr|H0YEU2|H0YEU2_HUMAN,tr|E9PL09|E9PL09_HUMAN,tr|E9PK82|E9PK82_HUMAN,tr|H0YES8|H0YES8_HUMAN,tr|F2Z2S8|F2Z2S8_HUMAN,tr|H0YCJ7|H0YCJ7_HUMAN,tr|E9PQ96|E9PQ96_HUMAN,tr|E9PJH4|E9PJH4_HUMAN,tr|E9PQX2|E9PQX2_HUMAN,tr|E9PPU1|E9PPU1_HUMAN" 11 895.4804 0.45 2936 14057 2 895.477998 448.7475 40S ribosomal protein S3 OS=Homo sapiens OX=9606 GN=RPS3 PE=1 SV=2 5.84 3031.4 - 376759 - - - -2.631 - 1.118 0.278 - 89.2 1 2 0 -0.0024 8 0 0 0 2.56E+07 5.64E+07 - - - 1.43 0.9976 221125_WJC_METTL3_EV_vs_WT_F01.14058.14058.2 0.0118 16-Oct K.TLAIELAPR.N "sp|P0CG22|DR4L1_HUMAN,sp|Q6PKH6|DR4L2_HUMAN,sp|Q9BTZ2|DHRS4_HUMAN,tr|A0A087WSZ6|A0A087WSZ6_HUMAN,tr|F6TD35|F6TD35_HUMAN,tr|F6VUV4|F6VUV4_HUMAN,tr|A0A087WXI8|A0A087WXI8_HUMAN,tr|H0YKN3|H0YKN3_HUMAN" 8 982.5811 1.47 2937 14058 2 982.578115 492.2978 Putative dehydrogenase\reductase SDR family member 4-like 1 OS=Homo sapiens OX=9606 GN=DHRS4L1 PE=5 SV=1 5.66 3031.5 - 2.32E+06 - - - -3.0695 - 1.815 0.3 - 385.3 1 2 0 -0.003 9 0 0 0 7.94E+08 5.42E+08 - - - 2.9804 0.9969 221125_WJC_METTL3_EV_vs_WT_F01.14060.14060.2 0.0254 12-May R.YFAC[160.03]LMR.A "sp|Q9Y6M9|NDUB9_HUMAN,tr|A0A7I2V620|A0A7I2V620_HUMAN,tr|A0A3B3IT57|A0A3B3IT57_HUMAN,tr|E7EWZ0|E7EWZ0_HUMAN,tr|E9PF49|E9PF49_HUMAN" 5 959.4357 3.35 2939 14060 2 959.435841 480.7251 NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 9 OS=Homo sapiens OX=9606 GN=NDUFB9 PE=1 SV=3 8.22 3031.8 - 744879 - - - 0.1167 - 1.123 0.279 - 60 1 2 0 0.0001 7 0 0 0 1.69E+07 5.05E+06 - - - 1.4692 0.988 221125_WJC_METTL3_EV_vs_WT_F01.14064.14064.2 5.01 12-Jul R.ELLEIVK[136.11].K sp|P31153|METK2_HUMAN 1 850.5255 0.56 2941 14064 2 850.523003 426.27 S-adenosylmethionine synthase isoform type-2 OS=Homo sapiens OX=9606 GN=MAT2A PE=1 SV=1 4.53 3032.3 - 798650 - - - -2.9593 - 1.571 0.144 - 208.1 1 2 0 -0.0025 7 0 0 0 2.93E+07 5.25E+07 - - - 1.5351 0.7841 221125_WJC_METTL3_EV_vs_WT_F01.14067.14067.2 0.311 12-Jul D.GVDSEIR.C "sp|Q9UBF8|PI4KB_HUMAN,tr|A0A0B4J1S8|A0A0B4J1S8_HUMAN,tr|A0A0A0MSL0|A0A0A0MSL0_HUMAN" 3 774.3872 51.87 2944 14067 2 774.384992 388.2009 Phosphatidylinositol 4-kinase beta OS=Homo sapiens OX=9606 GN=PI4KB PE=1 SV=1 4.37 3032.7 - 1.01E+06 - - - -2.828 - 1.617 0.227 - 167.9 1 1 0 -0.0022 7 0 0 0 6.84E+07 1.32E+06 - - - 2.2397 0.9993 221125_WJC_METTL3_EV_vs_WT_F01.14068.14068.2 0.00397 16-Aug R.IIPEITAMK[136.11].A sp|Q02880|TOP2B_HUMAN 1 1022.5926 1.43 2945 14068 2 1022.590782 512.3036 DNA topoisomerase 2-beta OS=Homo sapiens OX=9606 GN=TOP2B PE=1 SV=3 6 3032.8 - 764016 - - - -1.7329 - 1.599 0.389 - 158.3 1 2 0 -0.0018 9 0 0 0 3.13E+07 2.19E+07 - - - 3.2715 0.9543 221125_WJC_METTL3_EV_vs_WT_F01.14070.14070.2 0.000103 18-Nov R.VGPGPALMLR.G "sp|O15067|PUR4_HUMAN,tr|H0YGH1|H0YGH1_HUMAN" 2 1009.5743 0.48 2947 14070 2 1009.566994 505.7944 Phosphoribosylformylglycinamidine synthase OS=Homo sapiens OX=9606 GN=PFAS PE=1 SV=4 9.72 3033.1 - 511621 - - - -7.208 - 2.073 0.25 - 347.3 1 2 0 -0.0073 10 0 0 0 2.26E+07 4.76E+07 - - - 2.9201 0.9934 221125_WJC_METTL3_EV_vs_WT_F01.14073.14073.2 0.0459 14-Jul R.ELVITIAR[166.11].E "sp|Q9NWS0|PIHD1_HUMAN,tr|M0QYF4|M0QYF4_HUMAN,tr|M0QZZ1|M0QZZ1_HUMAN,tr|M0QXD5|M0QXD5_HUMAN,tr|M0R3A4|M0R3A4_HUMAN,tr|M0R028|M0R028_HUMAN,tr|M0QZ61|M0QZ61_HUMAN,tr|M0R2P8|M0R2P8_HUMAN,tr|M0QZM3|M0QZM3_HUMAN,tr|M0QYA2|M0QYA2_HUMAN" 10 923.5679 1.29 2948 14073 2 923.565265 462.7912 PIH1 domain-containing protein 1 OS=Homo sapiens OX=9606 GN=PIH1D1 PE=1 SV=1 6.1 3033.4 - 6.48E+06 - - - -2.8931 - 1.509 0.229 - 228.2 1 2 0 -0.0027 8 0 0 0 5.61E+08 4.34E+08 - - - 1.9725 0.8478 221125_WJC_METTL3_EV_vs_WT_F01.14078.14078.2 0.037 20-Sep R.VGAGAPVYMAA.V "sp|Q16777|H2A2C_HUMAN,sp|Q6FI13|H2A2A_HUMAN" 2 1005.4954 - 2951 14078 2 1005.493995 503.755 Histone H2A type 2-C OS=Homo sapiens OX=9606 GN=H2AC20 PE=1 SV=4 5.49 3034 - 726639 - - - -1.3496 - 1.219 0.295 - 157.1 1 1 0 -0.0014 11 0 0 0 - - - - - 1.7552 0.9994 221125_WJC_METTL3_EV_vs_WT_F01.14081.14081.2 0.000642 16-Aug R.VYSYALALK[136.11].H "sp|Q9UKK9|NUDT5_HUMAN,tr|A6NFX8|A6NFX8_HUMAN" 2 1034.5892 1.84 2952 14081 2 1034.587723 518.3019 ADP-sugar pyrophosphatase OS=Homo sapiens OX=9606 GN=NUDT5 PE=1 SV=1 8.47 3034.4 - 382971 - - - -1.4112 - 1.329 0.461 - 147.9 1 2 0 -0.0015 9 0 0 0 4.08E+07 2.22E+07 - - - 3.2683 0.9778 221125_WJC_METTL3_EV_vs_WT_F01.14083.14083.2 0.471 12-Jul R.LMDLLQK[136.11].K sp|Q9UJV9|DDX41_HUMAN 1 867.4979 0.94 2954 14083 2 867.496786 434.7562 Probable ATP-dependent RNA helicase DDX41 OS=Homo sapiens OX=9606 GN=DDX41 PE=1 SV=2 5.84 3034.6 - 2.67E+06 - - - -1.313 - 1.487 0.001 - 137.4 1 2 0 -0.0011 7 0 0 0 7.90E+07 8.43E+07 - - - 0.3052 0.9994 221125_WJC_METTL3_EV_vs_WT_F01.14084.14084.2 0.000126 16-Sep R.VYSYALALK.H "sp|Q9UKK9|NUDT5_HUMAN,tr|A6NFX8|A6NFX8_HUMAN" 2 1026.575 1.71 2955 14084 2 1026.576678 514.2948 ADP-sugar pyrophosphatase OS=Homo sapiens OX=9606 GN=NUDT5 PE=1 SV=1 8.47 3034.7 - 583389 - - - 1.6511 - 1.503 0.437 - 226.6 1 2 0 0.0017 9 0 0 0 3.74E+07 2.19E+07 - - - 3.447 0.9902 221125_WJC_METTL3_EV_vs_WT_F01.14092.14092.2 0.111 12-Jun R.LLC[160.03]NFMR[166.11].Q "sp|P25786|PSA1_HUMAN,tr|F5GX11|F5GX11_HUMAN,tr|B4DEV8|B4DEV8_HUMAN" 3 962.4705 0.77 2958 14092 2 962.467939 482.2426 Proteasome subunit alpha type-1 OS=Homo sapiens OX=9606 GN=PSMA1 PE=1 SV=1 8.25 3036 - 728298 - - - -2.7107 - 1.28 0.234 - 96.8 1 2 0 -0.0026 7 0 0 0 1.53E+07 1.99E+07 - - - 1.5507 0.9997 221125_WJC_METTL3_EV_vs_WT_F01.14096.14096.2 8.31E-05 14-Sep K.LYANMFER.L "sp|Q02790|FKBP4_HUMAN,tr|H0YFG2|H0YFG2_HUMAN" 2 1042.4906 1.36 2960 14096 2 1042.489397 522.2526 Peptidyl-prolyl cis-trans isomerase FKBP4 OS=Homo sapiens OX=9606 GN=FKBP4 PE=1 SV=3 6 3036.5 - 940331 - - - -1.1549 - 1.68 0.464 - 275.8 1 2 0 -0.0012 8 0 0 0 3.24E+07 2.38E+07 - - - 4.0324 0.928 221125_WJC_METTL3_EV_vs_WT_F01.14097.14097.2 0.0233 14-Jun L.GVIAEVDK[136.11].A sp|Q96N76|HUTU_HUMAN 1 837.4687 0.02 2961 14097 2 837.468192 419.7416 Urocanate hydratase OS=Homo sapiens OX=9606 GN=UROC1 PE=1 SV=1 4.37 3036.6 - 687720 - - - -0.646 - 1.483 0.267 - 86.7 1 1 0 -0.0005 8 0 0 0 9.43E+05 5.04E+07 - - - 2.2014 0.9481 221125_WJC_METTL3_EV_vs_WT_F01.14101.14101.2 0.842 16-Oct L.PGPLSPVAR.G sp|P48634|PRC2A_HUMAN 1 892.5131 1.83 2962 14101 2 892.513823 447.2638 Protein PRRC2A OS=Homo sapiens OX=9606 GN=PRRC2A PE=1 SV=3 10.18 3037.2 - 760526 - - - 0.865 - 1.983 0.221 - 322.1 1 1 0 0.0008 9 0 0 0 2.94E+07 1.61E+07 - - - 2.6537 0.9993 221125_WJC_METTL3_EV_vs_WT_F01.14106.14106.2 0.00303 16-Sep K.FVGNIYTLK[136.11].C "sp|O95785|WIZ_HUMAN,tr|A0A669KBG4|A0A669KBG4_HUMAN,tr|A0A2R8YFV2|A0A2R8YFV2_HUMAN,tr|A0A669KAV7|A0A669KAV7_HUMAN,tr|M0QXA7|M0QXA7_HUMAN,tr|A0A669KBH9|A0A669KBH9_HUMAN,tr|B9EGQ5|B9EGQ5_HUMAN" 7 1061.6001 1.17 2965 14106 2 1061.6009 531.8073 Protein Wiz OS=Homo sapiens OX=9606 GN=WIZ PE=1 SV=2 8.59 3037.8 - 1.62E+06 - - - 0.7705 - 1.437 0.369 - 195.2 1 2 0 0.0008 9 0 0 0 1.14E+08 9.76E+07 - - - 2.8151 0.9974 221125_WJC_METTL3_EV_vs_WT_F01.14107.14107.2 0.197 16-Jul K.LVTEPLVLK[136.11].S sp|O43896|KIF1C_HUMAN 1 1018.6518 0.15 2966 14107 2 1018.653197 510.3332 Kinesin-like protein KIF1C OS=Homo sapiens OX=9606 GN=KIF1C PE=1 SV=3 6 3037.9 - 781332 - - - 1.3881 - 1.415 0.261 - 139 1 2 0 0.0014 9 0 0 0 1.95E+07 1.31E+08 - - - 1.9726 0.9988 221125_WJC_METTL3_EV_vs_WT_F01.14110.14110.2 0.0216 16-Aug K.LVTEPLVLK.S sp|O43896|KIF1C_HUMAN 1 1010.6376 0.25 2969 14110 2 1010.63691 506.3261 Kinesin-like protein KIF1C OS=Homo sapiens OX=9606 GN=KIF1C PE=1 SV=3 6 3038.2 - 463975 - - - -0.6659 - 1.43 0.295 - 147.3 1 2 0 -0.0007 9 0 0 0 1.95E+07 7.85E+07 - - - 2.2544 0.9997 221125_WJC_METTL3_EV_vs_WT_F01.14115.14115.2 0.0211 14-Oct R.YADLLLEK.E sp|Q99459|CDC5L_HUMAN 1 963.5277 1.31 2972 14115 2 963.528017 482.7711 Cell division cycle 5-like protein OS=Homo sapiens OX=9606 GN=CDC5L PE=1 SV=2 4.37 3038.8 - 1.99E+06 - - - 0.3311 - 1.804 0.356 - 249.7 1 2 0 0.0003 8 0 0 0 3.52E+08 2.69E+08 - - - 3.4497 0.9959 221125_WJC_METTL3_EV_vs_WT_F01.14116.14116.2 1.21 12-Jul R.ELLEIVK.K sp|P31153|METK2_HUMAN 1 842.5113 0.55 2973 14116 2 842.509956 422.2629 S-adenosylmethionine synthase isoform type-2 OS=Homo sapiens OX=9606 GN=MAT2A PE=1 SV=1 4.53 3038.9 - 1.08E+06 - - - -1.619 - 1.586 0.152 - 201.2 1 2 0 -0.0014 7 0 0 0 2.93E+07 5.31E+07 - - - 1.6246 0.9984 221125_WJC_METTL3_EV_vs_WT_F01.14122.14122.2 0.0134 16-Sep K.FVGNIYTLK.C "sp|O95785|WIZ_HUMAN,tr|A0A669KBG4|A0A669KBG4_HUMAN,tr|A0A2R8YFV2|A0A2R8YFV2_HUMAN,tr|A0A669KAV7|A0A669KAV7_HUMAN,tr|M0QXA7|M0QXA7_HUMAN,tr|A0A669KBH9|A0A669KBH9_HUMAN,tr|B9EGQ5|B9EGQ5_HUMAN" 7 1053.5859 1.17 2977 14122 2 1053.584354 527.8002 Protein Wiz OS=Homo sapiens OX=9606 GN=WIZ PE=1 SV=2 8.59 3039.6 - 2.64E+06 - - - -1.4503 - 1.209 0.37 - 174 1 2 0 -0.0015 9 0 0 0 1.15E+08 9.76E+07 - - - 2.3224 0.9995 221125_WJC_METTL3_EV_vs_WT_F01.14123.14123.2 0.0861 16-Sep K.LGIIGVVNR[166.11].S "sp|O00429|DNM1L_HUMAN,tr|F8VZ52|F8VZ52_HUMAN" 2 949.5948 1.05 2978 14123 2 949.594533 475.8047 Dynamin-1-like protein OS=Homo sapiens OX=9606 GN=DNM1L PE=1 SV=2 9.75 3039.7 - 932733 - - - -0.3033 - 1.812 0.297 - 196.3 1 2 0 -0.0003 9 0 0 0 8.06E+07 7.66E+07 - - - 2.9543 0.9939 221125_WJC_METTL3_EV_vs_WT_F01.14124.14124.2 0.171 14-May K.LTPLLSVR.E "sp|Q9BXP5|SRRT_HUMAN,tr|H7C3A1|H7C3A1_HUMAN" 2 897.5648 1.08 2979 14124 2 897.564132 449.7897 Serrate RNA effector molecule homolog OS=Homo sapiens OX=9606 GN=SRRT PE=1 SV=1 9.75 3039.8 - 811156 - - - -0.6919 - 1.29 0.162 - 75.3 1 2 0 -0.0006 8 0 0 0 1.74E+08 1.61E+08 - - - 1.0053 0.9993 221125_WJC_METTL3_EV_vs_WT_F01.14130.14130.2 0.0131 18-Jul K.GVAYTLLTPK[136.11].D "sp|Q86XP3|DDX42_HUMAN,tr|A0A0A0MSJ0|A0A0A0MSJ0_HUMAN" 2 1069.6263 3.4 2983 14130 2 1069.625645 535.8204 ATP-dependent RNA helicase DDX42 OS=Homo sapiens OX=9606 GN=DDX42 PE=1 SV=1 8.59 3040.7 - 507436 - - - -0.6096 - 1.502 0.35 - 141.9 1 2 0 -0.0007 10 0 0 0 6.94E+07 2.04E+07 - - - 2.7614 0.9989 221125_WJC_METTL3_EV_vs_WT_F01.14136.14136.2 0.00864 12-Jul K.VSTVFWK[136.11].S sp|Q14152|EIF3A_HUMAN 1 873.484 0.68 2987 14136 2 873.484287 437.7493 Eukaryotic translation initiation factor 3 subunit A OS=Homo sapiens OX=9606 GN=EIF3A PE=1 SV=1 8.72 3041.4 - 1.75E+06 - - - 0.34 - 1.335 0.323 - 130.6 1 2 0 0.0003 7 0 0 0 2.44E+07 3.61E+07 - - - 2.3421 0.9989 221125_WJC_METTL3_EV_vs_WT_F01.14138.14138.2 0.054 14-Sep R.YADLLLEK[136.11].E sp|Q99459|CDC5L_HUMAN 1 971.5419 1.31 2989 14138 2 971.541791 486.7782 Cell division cycle 5-like protein OS=Homo sapiens OX=9606 GN=CDC5L PE=1 SV=2 4.37 3041.6 - 6.03E+06 - - - -0.1101 - 1.616 0.246 - 208.1 1 2 0 -0.0001 8 0 0 0 3.52E+08 2.69E+08 - - - 2.3054 0.9993 221125_WJC_METTL3_EV_vs_WT_F01.14145.14145.2 0.0112 14-Aug K.IIYIAPMR.S "sp|O75643|U520_HUMAN,tr|A0A494C1A5|A0A494C1A5_HUMAN" 2 975.5576 1.13 2995 14145 2 975.558229 488.7861 U5 small nuclear ribonucleoprotein 200 kDa helicase OS=Homo sapiens OX=9606 GN=SNRNP200 PE=1 SV=2 8.75 3042.3 - 6.66E+06 - - - 0.6868 - 1.556 0.343 - 235.5 1 2 0 0.0007 8 0 0 0 1.80E+08 1.59E+08 - - - 2.9076 0.9996 221125_WJC_METTL3_EV_vs_WT_F01.14149.14149.2 0.0711 16-Sep K.LGIIGVVNR.S "sp|O00429|DNM1L_HUMAN,tr|F8VZ52|F8VZ52_HUMAN" 2 939.5866 1.05 2998 14149 2 939.585813 470.8006 Dynamin-1-like protein OS=Homo sapiens OX=9606 GN=DNM1L PE=1 SV=2 9.75 3042.7 - 2.20E+06 - - - -0.7855 - 1.945 0.337 - 150.6 1 2 0 -0.0007 9 0 0 0 8.07E+07 7.66E+07 - - - 3.4545 0.9976 221125_WJC_METTL3_EV_vs_WT_F01.14152.14152.2 0.106 12-Jul K.VSTVFWK.S sp|Q14152|EIF3A_HUMAN 1 865.4698 0.69 3000 14152 2 865.469493 433.7422 Eukaryotic translation initiation factor 3 subunit A OS=Homo sapiens OX=9606 GN=EIF3A PE=1 SV=1 8.72 3043.1 - 1.21E+06 - - - -0.3432 - 1.366 0.221 - 133.5 1 2 0 -0.0003 7 0 0 0 2.25E+07 3.27E+07 - - - 1.6614 0.982 221125_WJC_METTL3_EV_vs_WT_F01.14154.14154.2 0.092 18-Aug K.IMLVEPPVAK[136.11].V sp|P18583|SON_HUMAN 1 1103.6504 1.66 3001 14154 2 1103.645549 552.8325 Protein SON OS=Homo sapiens OX=9606 GN=SON PE=1 SV=4 6 3043.3 - 627265 - - - -4.3981 - 1.558 0.239 - 149.6 1 2 0 -0.0049 10 0 0 0 1.53E+08 9.21E+07 - - - 2.0424 0.9993 221125_WJC_METTL3_EV_vs_WT_F01.14162.14162.2 0.0198 20-Aug M.VPPVQVSPLIK.L sp|P56385|ATP5I_HUMAN 1 1175.7278 1.83 3006 14162 2 1175.72694 588.8712 "ATP synthase subunit e, mitochondrial OS=Homo sapiens OX=9606 GN=ATP5ME PE=1 SV=2" 8.72 3044.3 - 224166 - - - -0.7272 - 1.337 0.39 - 107 1 2 0 -0.0009 11 0 0 0 6.12E+06 3.35E+06 - - - 2.7069 0.9964 221125_WJC_METTL3_EV_vs_WT_F01.14171.14171.2 14.7 12-Oct K.IGIEIIK[136.11].R "sp|P10809|CH60_HUMAN,tr|A0A7I2V2X6|A0A7I2V2X6_HUMAN,tr|A0A7I2YQK6|A0A7I2YQK6_HUMAN,tr|A0A7I2V599|A0A7I2V599_HUMAN" 4 792.52 1.2 3011 14171 2 792.519326 397.2673 "60 kDa heat shock protein, mitochondrial OS=Homo sapiens OX=9606 GN=HSPD1 PE=1 SV=2" 6 3045.4 - 8.16E+06 - - - -0.9022 - 2.009 0.026 - 249.4 1 2 0 -0.0007 7 0 0 0 1.61E+08 1.34E+08 - - - 1.4433 0.9998 221125_WJC_METTL3_EV_vs_WT_F01.14176.14176.2 0.000747 16-Sep R.MGPNIYELR[166.11].T "sp|Q9BPW8|NIPS1_HUMAN,tr|C9JDV8|C9JDV8_HUMAN,tr|H7C2U6|H7C2U6_HUMAN" 3 1101.5516 1.36 3013 14176 2 1101.550709 551.7831 Protein NipSnap homolog 1 OS=Homo sapiens OX=9606 GN=NIPSNAP1 PE=1 SV=1 5.75 3046.1 - 390706 - - - -0.8406 - 1.889 0.492 - 306.6 1 2 0 -0.0009 9 0 0 0 4.35E+07 3.20E+07 - - - 4.5147 0.9998 221125_WJC_METTL3_EV_vs_WT_F01.14177.14177.2 2.90E-05 16-Sep R.MGPNIYELR.T "sp|Q9BPW8|NIPS1_HUMAN,tr|C9JDV8|C9JDV8_HUMAN,tr|H7C2U6|H7C2U6_HUMAN" 3 1091.5434 1.36 3014 14177 2 1091.542601 546.779 Protein NipSnap homolog 1 OS=Homo sapiens OX=9606 GN=NIPSNAP1 PE=1 SV=1 5.75 3046.2 - 510170 - - - -0.6999 - 1.959 0.45 - 454.5 1 2 0 -0.0008 9 0 0 0 4.34E+07 3.20E+07 - - - 4.3098 0.994 221125_WJC_METTL3_EV_vs_WT_F01.14178.14178.2 0.137 12-Aug R.FLSEMLK.S sp|P15924|DESP_HUMAN 1 866.4572 19.7 3015 14178 2 866.455023 434.2359 Desmoplakin OS=Homo sapiens OX=9606 GN=DSP PE=1 SV=3 6 3046.2 - 1.11E+06 - - - -2.4848 - 1.399 0.23 - 173.6 1 2 0 -0.0022 7 0 0 0 3.62E+08 1.84E+07 - - - 1.803 0.9993 221125_WJC_METTL3_EV_vs_WT_F01.14182.14182.2 0.00256 16-Aug K.EIIDPVLDR.L "sp|P68366|TBA4A_HUMAN,tr|C9JJQ8|C9JJQ8_HUMAN,tr|C9JQ00|C9JQ00_HUMAN,tr|C9JEV8|C9JEV8_HUMAN" 4 1068.5815 11.98 3017 14182 2 1068.582869 535.298 Tubulin alpha-4A chain OS=Homo sapiens OX=9606 GN=TUBA4A PE=1 SV=1 4.03 3046.8 - 361597 - - - 1.2577 - 1.517 0.38 - 236.9 1 2 0 0.0013 9 0 0 0 3.11E+07 2.59E+06 - - - 3.0529 0.9907 221125_WJC_METTL3_EV_vs_WT_F01.14184.14184.2 0.142 14-May K.IIYIAPMR[166.11].S "sp|O75643|U520_HUMAN,tr|A0A494C1A5|A0A494C1A5_HUMAN" 2 985.5658 0.99 3019 14184 2 985.567373 493.7902 U5 small nuclear ribonucleoprotein 200 kDa helicase OS=Homo sapiens OX=9606 GN=SNRNP200 PE=1 SV=2 8.75 3047 - 2.87E+06 - - - 1.5666 - 1.341 0.173 - 57.9 2 2 0 0.0015 8 0 0 0 1.80E+08 1.83E+08 - - - 1.0688 0.9917 221125_WJC_METTL3_EV_vs_WT_F01.14185.14185.2 0.573 12-Jul R.VLVTVFR.Q "sp|O95163|ELP1_HUMAN,tr|A0A6Q8PFB7|A0A6Q8PFB7_HUMAN,tr|A0A6Q8PFH9|A0A6Q8PFH9_HUMAN,tr|A0A6Q8PH48|A0A6Q8PH48_HUMAN,tr|A0A6Q8PHC9|A0A6Q8PHC9_HUMAN,tr|A0A6Q8PHA0|A0A6Q8PHA0_HUMAN,tr|A0A6Q8PHI5|A0A6Q8PHI5_HUMAN,tr|A0A6Q8PF69|A0A6Q8PF69_HUMAN,tr|A0A6Q8PF66|A0A6Q8PF66_HUMAN,tr|A0A6Q8PGW3|A0A6Q8PGW3_HUMAN,tr|A0A6Q8PG86|A0A6Q8PG86_HUMAN,tr|A0A6Q8PGR0|A0A6Q8PGR0_HUMAN,tr|A0A6Q8PEX6|A0A6Q8PEX6_HUMAN,tr|F5H2T0|F5H2T0_HUMAN,tr|A0A6Q8PHF4|A0A6Q8PHF4_HUMAN,tr|A0A6Q8PFN8|A0A6Q8PFN8_HUMAN" 16 832.5171 0.74 3020 14185 2 832.516437 417.2658 Elongator complex protein 1 OS=Homo sapiens OX=9606 GN=ELP1 PE=1 SV=3 9.72 3047.1 - 352406 - - - -0.7651 - 1.382 0.101 - 155.9 1 2 0 -0.0006 7 0 0 0 1.44E+07 1.94E+07 - - - 0.8119 0.9997 221125_WJC_METTL3_EV_vs_WT_F01.14188.14188.2 0.000603 20-Sep K.DAVEDLESVGK.G sp|P81605|DCD_HUMAN 1 1160.5561 999 3021 14188 2 1160.556024 581.2853 Dermcidin OS=Homo sapiens OX=9606 GN=DCD PE=1 SV=2 3.92 3047.5 - 402980 - - - -0.0638 - 1.686 0.44 - 167.9 1 2 0 -0.0001 11 0 0 0 2.99E+06 0.00E+00 - - - 3.7039 0.9997 221125_WJC_METTL3_EV_vs_WT_F01.14196.14196.3 0.000934 Oct-48 R.GYFEYIEENKYSR.A "sp|Q00839|HNRPU_HUMAN,tr|Q5RI18|Q5RI18_HUMAN,tr|A0A1W2PP35|A0A1W2PP35_HUMAN,tr|A0A1W2PPS1|A0A1W2PPS1_HUMAN,tr|A0A1W2PRI6|A0A1W2PRI6_HUMAN" 5 1696.7733 0.97 3027 14196 3 1696.772595 566.5984 Heterogeneous nuclear ribonucleoprotein U OS=Homo sapiens OX=9606 GN=HNRNPU PE=1 SV=6 4.79 3048.5 - 187126 - - - -0.4167 - 2.057 0.464 - 98.3 1 2 1 -0.0007 13 0 0 0 3.60E+06 3.73E+06 - - - 5.6685 0.9985 221125_WJC_METTL3_EV_vs_WT_F01.14207.14207.2 0.081 14-Jul K.YGLKPPTL.- sp|O94826|TOM70_HUMAN 1 887.5117 1.73 3034 14207 2 887.512446 444.7631 Mitochondrial import receptor subunit TOM70 OS=Homo sapiens OX=9606 GN=TOMM70 PE=1 SV=1 8.59 3049.8 - 953348 - - - 0.8924 - 1.358 0.302 - 113.2 1 2 0 0.0008 8 0 0 0 4.41E+07 2.55E+07 - - - 2.1942 0.995 221125_WJC_METTL3_EV_vs_WT_F01.14213.14213.2 0.00984 12-Jul R.VAFVNFR.R "sp|Q96T37|RBM15_HUMAN,tr|A0A494C001|A0A494C001_HUMAN,tr|A0A499FJY3|A0A499FJY3_HUMAN,tr|A0A087WWP4|A0A087WWP4_HUMAN" 4 851.4654 1.01 3039 14213 2 851.465877 426.74 RNA-binding protein 15 OS=Homo sapiens OX=9606 GN=RBM15 PE=1 SV=2 9.72 3050.5 - 3.24E+06 - - - 0.5919 - 1.634 0.079 - 200.5 1 2 0 0.0005 7 0 0 0 6.62E+07 6.56E+07 - - - 1.1802 0.9979 221125_WJC_METTL3_EV_vs_WT_F01.14215.14215.2 0.0483 12-Jul K.VTFLITR[166.11].L "sp|A6ZKI3|RTL8C_HUMAN,sp|Q9BWD3|RTL8A_HUMAN,sp|Q17RB0|RTL8B_HUMAN" 3 858.5203 1.14 3041 14215 2 858.520835 430.2674 Retrotransposon Gag-like protein 8C OS=Homo sapiens OX=9606 GN=RTL8C PE=1 SV=1 9.72 3050.7 - 2.76E+06 - - - 0.6709 - 1.52 0.201 - 236.2 1 2 0 0.0006 7 0 0 0 1.03E+08 8.97E+07 - - - 1.8521 0.9043 221125_WJC_METTL3_EV_vs_WT_F01.14216.14216.2 0.37 12-Jun K.NVGIFLK.N sp|Q9Y5B9|SP16H_HUMAN 1 789.4749 0.87 3042 14216 2 789.475008 395.7447 FACT complex subunit SPT16 OS=Homo sapiens OX=9606 GN=SUPT16H PE=1 SV=1 8.75 3050.7 - 1.88E+06 - - - 0.1685 - 0.939 0.059 - 111.8 2 2 0 0.0001 7 0 0 0 1.24E+08 1.42E+08 - - - -0.8572 0.9673 221125_WJC_METTL3_EV_vs_WT_F01.14219.14219.2 2.38 12-Jul K.ILGIPYK.N "sp|Q9UIV8|SPB13_HUMAN,tr|A0A0A0MQW3|A0A0A0MQW3_HUMAN,tr|H7BZS9|H7BZS9_HUMAN" 3 802.4953 0.77 3045 14219 2 802.494927 402.2549 Serpin B13 OS=Homo sapiens OX=9606 GN=SERPINB13 PE=1 SV=2 8.59 3051 - 703192 - - - -0.4349 - 1.041 0.092 - 96.1 1 2 0 -0.0003 7 0 0 0 4.42E+07 5.74E+07 - - - -0.1523 0.9977 221125_WJC_METTL3_EV_vs_WT_F01.14223.14223.2 0.042 12-Jul K.VTFLITR.L "sp|A6ZKI3|RTL8C_HUMAN,sp|Q9BWD3|RTL8A_HUMAN,sp|Q17RB0|RTL8B_HUMAN" 3 848.512 1.14 3047 14223 2 848.512184 425.2633 Retrotransposon Gag-like protein 8C OS=Homo sapiens OX=9606 GN=RTL8C PE=1 SV=1 9.72 3051.5 - 3.02E+06 - - - 0.2298 - 1.489 0.189 - 270.9 1 2 0 0.0002 7 0 0 0 1.02E+08 8.97E+07 - - - 1.6983 0.9995 221125_WJC_METTL3_EV_vs_WT_F01.14224.14224.2 0.00121 14-Jul K.LLESDYFR[166.11].Y "sp|Q96HE7|ERO1A_HUMAN,tr|G3V503|G3V503_HUMAN,tr|G3V3E6|G3V3E6_HUMAN" 3 1051.5214 0.44 3048 14224 2 1051.522893 526.768 ERO1-like protein alpha OS=Homo sapiens OX=9606 GN=ERO1A PE=1 SV=2 4.37 3051.6 - 397065 - - - 1.4379 - 1.625 0.418 - 155.1 1 2 0 0.0015 8 0 0 0 5.65E+06 1.27E+07 - - - 3.5921 0.9996 221125_WJC_METTL3_EV_vs_WT_F01.14230.14230.2 0.0388 18-Oct R.VVVDALSGLK.G "sp|P12532|KCRU_HUMAN,tr|C9JSQ1|C9JSQ1_HUMAN,tr|F8WCN3|F8WCN3_HUMAN" 3 999.5964 1.94 3052 14230 2 999.59642 500.8055 "Creatine kinase U-type, mitochondrial OS=Homo sapiens OX=9606 GN=CKMT1A PE=1 SV=1" 5.81 3052.4 - 663167 - - - -0.027 - 1.846 0.346 - 182 1 2 0 0 10 0 0 0 1.48E+08 7.63E+07 - - - 3.3077 0.9847 221125_WJC_METTL3_EV_vs_WT_F01.14237.14237.2 0.566 12-Jun R.AVTIFIR[166.11].G "sp|P48643|TCPE_HUMAN,sp|Q6ZVL6|K154L_HUMAN,tr|E9PCA1|E9PCA1_HUMAN,tr|B7ZAR1|B7ZAR1_HUMAN,tr|E7ENZ3|E7ENZ3_HUMAN,tr|H0YDE5|H0YDE5_HUMAN,tr|A0A590UJI0|A0A590UJI0_HUMAN,tr|A0A5F9UK30|A0A5F9UK30_HUMAN" 8 828.5097 0.65 3057 14237 2 828.509311 415.2621 T-complex protein 1 subunit epsilon OS=Homo sapiens OX=9606 GN=CCT5 PE=1 SV=1 9.79 3053.2 - 5.48E+06 - - - -0.4623 - 1.314 0.06 - 174.1 1 2 0 -0.0004 7 0 0 0 2.55E+09 3.91E+09 - - - 0.3493 0.9824 221125_WJC_METTL3_EV_vs_WT_F01.14238.14238.2 6.7 12-Jun R.AVTIFIR.G "sp|P48643|TCPE_HUMAN,sp|Q6ZVL6|K154L_HUMAN,tr|E9PCA1|E9PCA1_HUMAN,tr|B7ZAR1|B7ZAR1_HUMAN,tr|E7ENZ3|E7ENZ3_HUMAN,tr|H0YDE5|H0YDE5_HUMAN,tr|A0A590UJI0|A0A590UJI0_HUMAN,tr|A0A5F9UK30|A0A5F9UK30_HUMAN" 8 818.5014 0.65 3058 14238 2 818.501077 410.258 T-complex protein 1 subunit epsilon OS=Homo sapiens OX=9606 GN=CCT5 PE=1 SV=1 9.79 3053.3 - 2.33E+06 - - - -0.4239 - 1.196 0.087 - 166 1 2 0 -0.0003 7 0 0 0 2.55E+09 3.91E+09 - - - 0.2506 0.9745 221125_WJC_METTL3_EV_vs_WT_F01.14239.14239.2 7.84 12-Jul K.LVLILNK.S "sp|Q9BVP2|GNL3_HUMAN,sp|Q96RW7|HMCN1_HUMAN" 2 811.5531 1.11 3059 14239 2 811.552624 406.7838 Guanine nucleotide-binding protein-like 3 OS=Homo sapiens OX=9606 GN=GNL3 PE=1 SV=2 8.75 3053.4 - 1.23E+06 - - - -0.6173 - 1.365 0.001 - 208.2 1 2 0 -0.0005 7 0 0 0 6.33E+07 5.72E+07 - - - 0.0341 0.9996 221125_WJC_METTL3_EV_vs_WT_F01.14240.14240.2 0.224 18-Jul R.VLLGEGVLTK.E "sp|Q96S99|PKHF1_HUMAN,sp|Q9H8W4|PKHF2_HUMAN,tr|K7ELB8|K7ELB8_HUMAN,tr|K7EIX0|K7EIX0_HUMAN" 4 1027.6277 2.14 3060 14240 2 1027.627765 514.8211 Pleckstrin homology domain-containing family F member 1 OS=Homo sapiens OX=9606 GN=PLEKHF1 PE=1 SV=3 5.97 3053.5 - 471671 - - - 0.0175 - 1.635 0.385 - 110.5 1 2 0 0 10 0 0 0 4.18E+07 1.95E+07 - - - 3.2569 0.9964 221125_WJC_METTL3_EV_vs_WT_F01.14247.14247.2 0.574 12-Jul R.YIELLTR.S sp|P15924|DESP_HUMAN 1 906.5175 33.31 3065 14247 2 906.516825 454.266 Desmoplakin OS=Homo sapiens OX=9606 GN=DSP PE=1 SV=3 6 3054.3 - 2.77E+06 - - - -0.7093 - 1.326 0.198 - 187.1 1 2 0 -0.0006 7 0 0 0 6.41E+08 1.93E+07 - - - 1.3973 0.9993 221125_WJC_METTL3_EV_vs_WT_F01.14250.14250.2 0.0158 16-Oct R.VLDELTLAR.A "sp|Q04695|K1C17_HUMAN,sp|P02533|K1C14_HUMAN,sp|P08727|K1C19_HUMAN,sp|P08779|K1C16_HUMAN,sp|P19012|K1C15_HUMAN,tr|K7EPJ9|K7EPJ9_HUMAN,tr|C9JM50|C9JM50_HUMAN,tr|C9JTG5|C9JTG5_HUMAN,tr|F5GWP8|F5GWP8_HUMAN,tr|K7EMS3|K7EMS3_HUMAN,tr|A8MT21|A8MT21_HUMAN" 11 1028.5866 101365.66 3066 14250 2 1028.584985 515.3006 "Keratin, type I cytoskeletal 17 OS=Homo sapiens OX=9606 GN=KRT17 PE=1 SV=2" 4.37 3054.7 - 1.02E+06 - - - -1.5798 - 1.913 0.304 - 311.7 1 2 0 -0.0016 9 0 0 0 7.18E+10 7.08E+05 - - - 3.1625 0.8058 221125_WJC_METTL3_EV_vs_WT_F01.14252.14252.2 0.00356 14-Jun Y.RDLQIYSR[166.11].Q "sp|O00159|MYO1C_HUMAN,tr|I3L3Y6|I3L3Y6_HUMAN,tr|I3L3F5|I3L3F5_HUMAN,tr|F5H6E2|F5H6E2_HUMAN,tr|I3L501|I3L501_HUMAN" 5 1059.5701 - 3068 14252 2 1059.568969 530.7923 Unconventional myosin-Ic OS=Homo sapiens OX=9606 GN=MYO1C PE=1 SV=4 8.75 3054.9 - 891411 - - - -1.0316 - 1.771 0.116 - 126 3 1 0 -0.0011 8 0 0 0 - - - - - 1.4081 0.999 221125_WJC_METTL3_EV_vs_WT_F01.14258.14258.2 0.0712 14-Aug R.VPTWGPLR.G "sp|Q12906|ILF3_HUMAN,tr|K7EQR9|K7EQR9_HUMAN,tr|K7EKJ9|K7EKJ9_HUMAN" 3 924.5181 0.78 3071 14258 2 924.51721 463.2663 Interleukin enhancer-binding factor 3 OS=Homo sapiens OX=9606 GN=ILF3 PE=1 SV=3 9.72 3055.8 - 568519 - - - -1.0027 - 1.7 0.252 - 217.8 1 2 0 -0.0009 8 0 0 0 3.08E+07 3.94E+07 - - - 2.5023 0.9669 221125_WJC_METTL3_EV_vs_WT_F01.14264.14264.2 0.000243 16-Jul A.YC[160.03]TGLLLAR[166.11].R "sp|P46777|RL5_HUMAN,tr|A0A2R8Y6J3|A0A2R8Y6J3_HUMAN,tr|A0A2R8Y4A2|A0A2R8Y4A2_HUMAN,tr|Q5T7N0|Q5T7N0_HUMAN" 4 1075.5724 0.65 3075 14264 2 1075.570302 538.7935 60S ribosomal protein L5 OS=Homo sapiens OX=9606 GN=RPL5 PE=1 SV=3 8.22 3056.5 - 645436 - - - -1.9236 - 1.651 0.43 - 156.1 1 1 0 -0.0021 9 0 0 0 9.80E+06 1.52E+07 - - - 3.6669 0.9775 221125_WJC_METTL3_EV_vs_WT_F01.14269.14269.2 0.192 18-Oct R.LLENMTEVVR.K "sp|Q6P996|PDXD1_HUMAN,tr|H3BND4|H3BND4_HUMAN" 2 1202.6329 5.84 3077 14269 2 1202.627405 602.3237 Pyridoxal-dependent decarboxylase domain-containing protein 1 OS=Homo sapiens OX=9606 GN=PDXDC1 PE=1 SV=2 4.53 3057.1 - 409562 - - - -4.5766 - 1.63 0.211 - 312 1 2 0 -0.0055 10 0 0 0 1.17E+07 2.00E+06 - - - 1.9615 0.9989 221125_WJC_METTL3_EV_vs_WT_F01.14271.14271.2 0.173 18-Sep R.VLLGEGVLTK[136.11].E "sp|Q96S99|PKHF1_HUMAN,sp|Q9H8W4|PKHF2_HUMAN,tr|K7ELB8|K7ELB8_HUMAN,tr|K7EIX0|K7EIX0_HUMAN" 4 1035.6419 2.14 3078 14271 2 1035.640593 518.8282 Pleckstrin homology domain-containing family F member 1 OS=Homo sapiens OX=9606 GN=PLEKHF1 PE=1 SV=3 5.97 3057.4 - 949078 - - - -1.3074 - 1.555 0.317 - 158.9 1 2 0 -0.0014 10 0 0 0 4.18E+07 1.95E+07 - - - 2.6142 0.9985 221125_WJC_METTL3_EV_vs_WT_F01.14276.14276.2 0.000331 12-Aug K.FDLMYAK[136.11].R "sp|Q9NY65|TBA8_HUMAN,sp|Q6PEY2|TBA3E_HUMAN,sp|P0DPH7|TBA3C_HUMAN,sp|Q71U36|TBA1A_HUMAN,sp|P0DPH8|TBA3D_HUMAN,sp|A6NHL2|TBAL3_HUMAN,sp|P68366|TBA4A_HUMAN,sp|P68363|TBA1B_HUMAN,sp|Q9BQE3|TBA1C_HUMAN,tr|F5H5D3|F5H5D3_HUMAN,tr|C9J2C0|C9J2C0_HUMAN,tr|V9GZ17|V9GZ17_HUMAN,tr|A0A7P0T945|A0A7P0T945_HUMAN" 13 894.4401 0.54 3080 14276 2 894.437992 448.2273 Tubulin alpha-8 chain OS=Homo sapiens OX=9606 GN=TUBA8 PE=1 SV=1 5.83 3058 - 1.42E+06 - - - -2.3299 - 1.669 0.304 - 192.4 1 2 0 -0.0021 7 0 0 0 8.74E+08 1.63E+09 - - - 2.9087 0.9912 221125_WJC_METTL3_EV_vs_WT_F01.14284.14284.2 2.43 14-Jun R.ELVITIAR.E "sp|Q9NWS0|PIHD1_HUMAN,tr|M0QYF4|M0QYF4_HUMAN,tr|M0QZZ1|M0QZZ1_HUMAN,tr|M0QXD5|M0QXD5_HUMAN,tr|M0R3A4|M0R3A4_HUMAN,tr|M0R028|M0R028_HUMAN,tr|M0QZ61|M0QZ61_HUMAN,tr|M0R2P8|M0R2P8_HUMAN,tr|M0QZM3|M0QZM3_HUMAN,tr|M0QYA2|M0QYA2_HUMAN" 10 913.5597 1.58 3083 14284 2 913.557809 457.7871 PIH1 domain-containing protein 1 OS=Homo sapiens OX=9606 GN=PIH1D1 PE=1 SV=1 6.1 3059 - 1.39E+06 - - - -2.0338 - 1.437 0.153 - 114.8 1 2 0 -0.0019 8 0 0 0 5.63E+07 3.56E+07 - - - 1.2639 0.9996 221125_WJC_METTL3_EV_vs_WT_F01.14297.14297.2 0.00117 12-Aug K.FDLMYAK.R "sp|Q9NY65|TBA8_HUMAN,sp|Q6PEY2|TBA3E_HUMAN,sp|P0DPH7|TBA3C_HUMAN,sp|Q71U36|TBA1A_HUMAN,sp|P0DPH8|TBA3D_HUMAN,sp|A6NHL2|TBAL3_HUMAN,sp|P68366|TBA4A_HUMAN,sp|P68363|TBA1B_HUMAN,sp|Q9BQE3|TBA1C_HUMAN,tr|F5H5D3|F5H5D3_HUMAN,tr|C9J2C0|C9J2C0_HUMAN,tr|V9GZ17|V9GZ17_HUMAN,tr|A0A7P0T945|A0A7P0T945_HUMAN" 13 886.4259 0.54 3087 14297 2 886.425233 444.2202 Tubulin alpha-8 chain OS=Homo sapiens OX=9606 GN=TUBA8 PE=1 SV=1 5.83 3060.9 - 4.08E+06 - - - -0.7254 - 1.601 0.365 - 184.9 1 2 0 -0.0006 7 0 0 0 8.73E+08 1.63E+09 - - - 3.2279 0.9398 221125_WJC_METTL3_EV_vs_WT_F01.14302.14302.2 0.118 12-Jul R.IVFQEFR[166.11].Q "sp|P35580|MYH10_HUMAN,sp|P35749|MYH11_HUMAN" 2 947.5104 0.91 3090 14302 2 947.504968 474.7625 Myosin-10 OS=Homo sapiens OX=9606 GN=MYH10 PE=1 SV=3 6 3061.4 - 4.01E+06 - - - -5.7561 - 1.434 0.221 - 185 1 2 0 -0.0055 7 0 0 0 3.25E+08 3.56E+08 - - - 1.8138 0.9991 221125_WJC_METTL3_EV_vs_WT_F01.14306.14306.2 0.000415 16-Sep R.VVFAELAC[160.03]R[166.11].E "sp|Q8NE71|ABCF1_HUMAN,tr|A0A0G2JIC2|A0A0G2JIC2_HUMAN,tr|Q5STZ8|Q5STZ8_HUMAN,tr|H0YGW7|H0YGW7_HUMAN" 4 1073.5567 0.52 3094 14306 2 1073.554526 537.7856 ATP-binding cassette sub-family F member 1 OS=Homo sapiens OX=9606 GN=ABCF1 PE=1 SV=2 5.97 3062 - 995098 - - - -2.0446 - 1.994 0.3 - 367.1 1 2 0 -0.0022 9 0 0 0 2.72E+07 5.28E+07 - - - 3.2527 0.9969 221125_WJC_METTL3_EV_vs_WT_F01.14312.14312.2 0.138 12-Jul K.FLSVLER[166.11].Q sp|P07099|HYEP_HUMAN 1 872.4995 1.01 3098 14312 2 872.499718 437.257 Epoxide hydrolase 1 OS=Homo sapiens OX=9606 GN=EPHX1 PE=1 SV=1 6 3062.7 - 2.61E+06 - - - 0.2235 - 1.453 0.17 - 142.4 1 2 0 0.0002 7 0 0 0 1.07E+08 1.06E+08 - - - 1.4804 0.9947 221125_WJC_METTL3_EV_vs_WT_F01.14315.14315.2 0.33 12-Aug K.FLSVLER.Q sp|P07099|HYEP_HUMAN 1 862.4913 1 3100 14315 2 862.489835 432.2529 Epoxide hydrolase 1 OS=Homo sapiens OX=9606 GN=EPHX1 PE=1 SV=1 6 3063.1 - 1.48E+06 - - - -1.6441 - 1.446 0.167 - 222.4 1 2 0 -0.0014 7 0 0 0 1.07E+08 1.06E+08 - - - 1.4426 0.9681 221125_WJC_METTL3_EV_vs_WT_F01.14323.14323.2 0.204 14-Aug V.LDELTLAR.A "sp|Q04695|K1C17_HUMAN,sp|P02533|K1C14_HUMAN,sp|P08727|K1C19_HUMAN,sp|P08779|K1C16_HUMAN,sp|P19012|K1C15_HUMAN,tr|K7EPJ9|K7EPJ9_HUMAN,tr|C9JM50|C9JM50_HUMAN,tr|C9JTG5|C9JTG5_HUMAN,tr|F5GWP8|F5GWP8_HUMAN,tr|K7EMS3|K7EMS3_HUMAN,tr|A8MT21|A8MT21_HUMAN" 11 929.5182 999 3104 14323 2 929.519168 465.7664 "Keratin, type I cytoskeletal 17 OS=Homo sapiens OX=9606 GN=KRT17 PE=1 SV=2" 4.37 3064.1 - 8.67E+06 - - - 1.0457 - 1.998 0.286 - 230.3 1 1 0 0.001 8 0 0 0 1.23E+08 0.00E+00 - - - 3.2406 0.9411 221125_WJC_METTL3_EV_vs_WT_F01.14328.14328.2 0.13 12-Jul K.YVLALVK.K "sp|Q5T8P6|RBM26_HUMAN,tr|A0A087X0H9|A0A087X0H9_HUMAN" 2 804.5109 0.78 3106 14328 2 804.508079 403.2627 RNA-binding protein 26 OS=Homo sapiens OX=9606 GN=RBM26 PE=1 SV=3 8.59 3064.7 - 8.38E+06 - - - -3.5388 - 1.042 0.221 - 115.5 2 2 0 -0.0028 7 0 0 0 6.69E+07 8.63E+07 - - - 0.6683 0.8735 221125_WJC_METTL3_EV_vs_WT_F01.14330.14330.2 4.67 12-Jul K.LGFEEFK.Y "sp|P04632|CPNS1_HUMAN,sp|Q96L46|CPNS2_HUMAN,tr|A0A075B7C0|A0A075B7C0_HUMAN,tr|A0A0C4DGQ5|A0A0C4DGQ5_HUMAN,tr|K7ELJ7|K7ELJ7_HUMAN,tr|U3KPR7|U3KPR7_HUMAN,tr|U3KQE2|U3KQE2_HUMAN,tr|K7EIV0|K7EIV0_HUMAN,tr|K7EKD8|K7EKD8_HUMAN" 9 868.4331 1.42 3107 14330 2 868.430638 435.2238 Calpain small subunit 1 OS=Homo sapiens OX=9606 GN=CAPNS1 PE=1 SV=1 4.53 3064.9 - 1.49E+06 - - - -2.8004 - 1.01 0.095 - 108 1 2 0 -0.0024 7 0 0 0 3.77E+08 2.65E+08 - - - -0.2266 0.9978 221125_WJC_METTL3_EV_vs_WT_F01.14336.14336.2 0.0171 16-Oct K.LISYSYMVR.G sp|P07099|HYEP_HUMAN 1 1130.5794 1.03 3109 14336 2 1130.575144 566.297 Epoxide hydrolase 1 OS=Homo sapiens OX=9606 GN=EPHX1 PE=1 SV=1 8.59 3065.7 - 760497 - - - -3.7786 - 1.87 0.38 - 285.5 1 2 0 -0.0043 9 0 0 0 3.06E+07 2.98E+07 - - - 3.6572 0.9984 221125_WJC_METTL3_EV_vs_WT_F01.14339.14339.2 2.18 14-Oct R.LIEILSEK.A "sp|Q9P2E9|RRBP1_HUMAN,tr|A0A087WVV2|A0A087WVV2_HUMAN,tr|F8W7S5|F8W7S5_HUMAN" 3 943.559 1.62 3110 14339 2 943.557743 472.7868 Ribosome-binding protein 1 OS=Homo sapiens OX=9606 GN=RRBP1 PE=1 SV=5 4.53 3066.1 - 5.59E+06 - - - -1.3311 - 1.606 0.244 - 275.2 1 2 0 -0.0013 8 0 0 0 1.51E+08 9.31E+07 - - - 2.2716 0.9782 221125_WJC_METTL3_EV_vs_WT_F01.14340.14340.2 0.107 12-Jun K.LGFEEFK[136.11].Y "sp|P04632|CPNS1_HUMAN,sp|Q96L46|CPNS2_HUMAN,tr|A0A075B7C0|A0A075B7C0_HUMAN,tr|A0A0C4DGQ5|A0A0C4DGQ5_HUMAN,tr|K7ELJ7|K7ELJ7_HUMAN,tr|U3KPR7|U3KPR7_HUMAN,tr|U3KQE2|U3KQE2_HUMAN,tr|K7EIV0|K7EIV0_HUMAN,tr|K7EKD8|K7EKD8_HUMAN" 9 876.4473 1.42 3111 14340 2 876.444523 439.2309 Calpain small subunit 1 OS=Homo sapiens OX=9606 GN=CAPNS1 PE=1 SV=1 4.53 3066.3 - 1.92E+06 - - - -3.1342 - 1.307 0.175 - 73.4 1 2 0 -0.0027 7 0 0 0 3.77E+08 2.65E+08 - - - 1.181 0.9527 221125_WJC_METTL3_EV_vs_WT_F01.14341.14341.2 0.0425 14-Jul K.LLFYATSR[166.11].A "sp|Q7Z2W4|ZCCHV_HUMAN,tr|C9J6P4|C9J6P4_HUMAN,tr|A0A7P0T8C6|A0A7P0T8C6_HUMAN" 3 979.5366 0.63 3112 14341 2 979.53055 490.7756 Zinc finger CCCH-type antiviral protein 1 OS=Homo sapiens OX=9606 GN=ZC3HAV1 PE=1 SV=3 8.75 3066.4 - 2.46E+06 - - - -6.2142 - 1.439 0.291 - 175.6 1 2 0 -0.0061 8 0 0 0 5.32E+07 8.44E+07 - - - 2.2861 0.9972 221125_WJC_METTL3_EV_vs_WT_F01.14344.14344.2 0.0911 14-Jul R.ELVITIAR[166.11].E "sp|Q9NWS0|PIHD1_HUMAN,tr|M0QYF4|M0QYF4_HUMAN,tr|M0QZZ1|M0QZZ1_HUMAN,tr|M0QXD5|M0QXD5_HUMAN,tr|M0R3A4|M0R3A4_HUMAN,tr|M0R028|M0R028_HUMAN,tr|M0QZ61|M0QZ61_HUMAN,tr|M0R2P8|M0R2P8_HUMAN,tr|M0QZM3|M0QZM3_HUMAN,tr|M0QYA2|M0QYA2_HUMAN" 10 923.5679 1.38 3113 14344 2 923.568774 462.7912 PIH1 domain-containing protein 1 OS=Homo sapiens OX=9606 GN=PIH1D1 PE=1 SV=1 6.1 3066.8 - 943525 - - - 0.9063 - 1.486 0.199 - 177.3 1 2 0 0.0008 8 0 0 0 9.36E+07 6.77E+07 - - - 1.7051 0.926 221125_WJC_METTL3_EV_vs_WT_F01.14353.14353.2 0.00309 20-Jul R.SLYASSPGGVY.A "sp|P08670|VIME_HUMAN,tr|B0YJC4|B0YJC4_HUMAN,tr|A0A1B0GVG8|A0A1B0GVG8_HUMAN,tr|A0A1B0GTT5|A0A1B0GTT5_HUMAN" 4 1099.5186 - 3116 14353 2 1099.517818 550.7666 Vimentin OS=Homo sapiens OX=9606 GN=VIM PE=1 SV=4 5.24 3068 - 1.03E+06 - - - -0.7021 - 1.175 0.367 - 104.6 1 1 0 -0.0008 11 0 0 0 - - - - - 2.1877 0.9855 221125_WJC_METTL3_EV_vs_WT_F01.14358.14358.2 0.741 14-Sep R.LYELDGLR.E "sp|Q9Y5K5|UCHL5_HUMAN,tr|H0Y4E0|H0Y4E0_HUMAN,tr|Q5LJA9|Q5LJA9_HUMAN,tr|H0Y6Y4|H0Y6Y4_HUMAN,tr|Q5LJB0|Q5LJB0_HUMAN,tr|Q5LJA5|Q5LJA5_HUMAN" 6 977.5182 1.77 3117 14358 2 977.514338 489.7664 Ubiquitin carboxyl-terminal hydrolase isozyme L5 OS=Homo sapiens OX=9606 GN=UCHL5 PE=1 SV=3 4.37 3068.8 - 3.10E+06 - - - -3.9467 - 1.587 0.206 - 330.1 1 2 0 -0.0039 8 0 0 0 1.26E+09 7.14E+08 - - - 1.9542 0.9449 221125_WJC_METTL3_EV_vs_WT_F01.14359.14359.2 0.0573 14-Sep R.LYELDGLR[166.11].E "sp|Q9Y5K5|UCHL5_HUMAN,tr|H0Y4E0|H0Y4E0_HUMAN,tr|Q5LJA9|Q5LJA9_HUMAN,tr|H0Y6Y4|H0Y6Y4_HUMAN,tr|Q5LJB0|Q5LJB0_HUMAN,tr|Q5LJA5|Q5LJA5_HUMAN" 6 987.5265 1.76 3118 14359 2 987.519081 494.7705 Ubiquitin carboxyl-terminal hydrolase isozyme L5 OS=Homo sapiens OX=9606 GN=UCHL5 PE=1 SV=3 4.37 3068.9 - 2.25E+06 - - - -7.4783 - 1.77 0.287 - 342.5 1 2 0 -0.0074 8 0 0 0 1.25E+09 7.14E+08 - - - 2.8805 0.9925 221125_WJC_METTL3_EV_vs_WT_F01.14377.14377.2 0.447 14-Jun R.IVAEEFLK[136.11].N "sp|P59998|ARPC4_HUMAN,tr|H7C0A3|H7C0A3_HUMAN,tr|F8WCF6|F8WCF6_HUMAN,tr|R4GN08|R4GN08_HUMAN" 4 955.547 0.6 3126 14377 2 955.545275 478.7808 Actin-related protein 2\3 complex subunit 4 OS=Homo sapiens OX=9606 GN=ARPC4 PE=1 SV=3 4.53 3071.2 - 1.11E+06 - - - -1.7885 - 1.315 0.189 - 59.8 1 2 0 -0.0017 8 0 0 0 2.87E+07 4.82E+07 - - - 1.2623 0.9808 221125_WJC_METTL3_EV_vs_WT_F01.14393.14393.2 0.207 12-Jul R.IFLQDIK[136.11].K "sp|P02794|FRIH_HUMAN,tr|E9PRK8|E9PRK8_HUMAN,tr|E9PKY7|E9PKY7_HUMAN,tr|G3V1D1|G3V1D1_HUMAN,tr|E9PPQ4|E9PPQ4_HUMAN,tr|G3V192|G3V192_HUMAN" 6 883.5259 1.27 3133 14393 2 883.523458 442.7702 Ferritin heavy chain OS=Homo sapiens OX=9606 GN=FTH1 PE=1 SV=2 5.84 3073.2 - 2.71E+06 - - - -2.7119 - 1.442 0.115 - 145.1 1 2 0 -0.0024 7 0 0 0 1.31E+08 1.03E+08 - - - 1.0494 0.9995 221125_WJC_METTL3_EV_vs_WT_F01.14397.14397.2 0.0794 16-Sep R.AFSYYGPLR[166.11].T "sp|Q16629|SRSF7_HUMAN,tr|C9JAB2|C9JAB2_HUMAN,tr|A0A0B4J1Z1|A0A0B4J1Z1_HUMAN" 3 1082.5425 1.29 3135 14397 2 1082.541065 542.2785 Serine\arginine-rich splicing factor 7 OS=Homo sapiens OX=9606 GN=SRSF7 PE=1 SV=1 8.63 3073.8 - 1.06E+06 - - - -1.2803 - 1.768 0.376 - 308.7 1 2 0 -0.0014 9 0 0 0 2.87E+08 2.23E+08 - - - 3.4663 0.9998 221125_WJC_METTL3_EV_vs_WT_F01.14404.14404.2 0.0344 20-Nov K.ILQLVATGAVR.D "sp|P47897|SYQ_HUMAN,tr|B4DDN1|B4DDN1_HUMAN,tr|H7C0R3|H7C0R3_HUMAN,tr|A0A1B0GTT3|A0A1B0GTT3_HUMAN,tr|A0A1B0GVU9|A0A1B0GVU9_HUMAN,tr|A0A0U1RQQ5|A0A0U1RQQ5_HUMAN" 6 1139.7026 1.12 3139 14404 2 1139.702433 570.8586 Glutamine--tRNA ligase OS=Homo sapiens OX=9606 GN=QARS1 PE=1 SV=1 9.75 3074.6 - 696934 - - - -0.1843 - 2.202 0.386 - 391.1 1 2 0 -0.0002 11 0 0 0 2.40E+07 2.14E+07 - - - 4.0274 0.9997 221125_WJC_METTL3_EV_vs_WT_F01.14410.14410.2 0.00527 14/20 K.ILQLVATGAVR[166.11].D "sp|P47897|SYQ_HUMAN,tr|B4DDN1|B4DDN1_HUMAN,tr|H7C0R3|H7C0R3_HUMAN,tr|A0A1B0GTT3|A0A1B0GTT3_HUMAN,tr|A0A1B0GVU9|A0A1B0GVU9_HUMAN,tr|A0A0U1RQQ5|A0A0U1RQQ5_HUMAN" 6 1149.7109 1.12 3143 14410 2 1149.709203 575.8627 Glutamine--tRNA ligase OS=Homo sapiens OX=9606 GN=QARS1 PE=1 SV=1 9.75 3075.5 - 818091 - - - -1.4873 - 2.321 0.352 - 952.4 1 2 0 -0.0017 11 0 0 0 2.40E+07 2.14E+07 - - - 3.9181 0.9984 221125_WJC_METTL3_EV_vs_WT_F01.14412.14412.2 0.00204 12-Aug K.FADFMVK.D "sp|P41250|GARS_HUMAN,tr|H7C443|H7C443_HUMAN,tr|A0A6Q8PGI6|A0A6Q8PGI6_HUMAN,tr|A0A6Q8PGA8|A0A6Q8PGA8_HUMAN,tr|A0A6Q8PGW4|A0A6Q8PGW4_HUMAN,tr|A0A6Q8PGZ8|A0A6Q8PGZ8_HUMAN,tr|A0A6Q8PH49|A0A6Q8PH49_HUMAN,tr|A0A6Q8PHH9|A0A6Q8PHH9_HUMAN,tr|A0A6Q8PF45|A0A6Q8PF45_HUMAN,tr|A0A6Q8PGN7|A0A6Q8PGN7_HUMAN,tr|A0A6Q8PGZ9|A0A6Q8PGZ9_HUMAN,tr|A0A6Q8PHI7|A0A6Q8PHI7_HUMAN,tr|A0A6Q8PFZ6|A0A6Q8PFZ6_HUMAN,tr|F8WCK4|F8WCK4_HUMAN" 14 856.4153 1.35 3145 14412 2 856.411908 429.2149 Glycine--tRNA ligase OS=Homo sapiens OX=9606 GN=GARS1 PE=1 SV=3 5.84 3075.7 - 1.43E+06 - - - -3.9735 - 1.708 0.473 - 161.1 1 2 0 -0.0034 7 0 0 0 6.49E+07 4.82E+07 - - - 4.2297 0.9973 221125_WJC_METTL3_EV_vs_WT_F01.14418.14418.2 0.167 12-Aug K.FADFMVK[136.11].D "sp|P41250|GARS_HUMAN,tr|H7C443|H7C443_HUMAN,tr|A0A6Q8PGI6|A0A6Q8PGI6_HUMAN,tr|A0A6Q8PGA8|A0A6Q8PGA8_HUMAN,tr|A0A6Q8PGW4|A0A6Q8PGW4_HUMAN,tr|A0A6Q8PGZ8|A0A6Q8PGZ8_HUMAN,tr|A0A6Q8PH49|A0A6Q8PH49_HUMAN,tr|A0A6Q8PHH9|A0A6Q8PHH9_HUMAN,tr|A0A6Q8PF45|A0A6Q8PF45_HUMAN,tr|A0A6Q8PGN7|A0A6Q8PGN7_HUMAN,tr|A0A6Q8PGZ9|A0A6Q8PGZ9_HUMAN,tr|A0A6Q8PHI7|A0A6Q8PHI7_HUMAN,tr|A0A6Q8PFZ6|A0A6Q8PFZ6_HUMAN,tr|F8WCK4|F8WCK4_HUMAN" 14 864.4295 1.4 3148 14418 2 864.426174 433.222 Glycine--tRNA ligase OS=Homo sapiens OX=9606 GN=GARS1 PE=1 SV=3 5.84 3076.5 - 1.87E+06 - - - -3.8603 - 1.766 0.358 - 153.9 1 2 0 -0.0033 7 0 0 0 6.76E+07 4.81E+07 - - - 3.4862 0.9952 221125_WJC_METTL3_EV_vs_WT_F01.14419.14419.2 1.12 14-Jun K.IEPPGLFR.G "sp|P11387|TOP1_HUMAN,sp|Q969P6|TOP1M_HUMAN,tr|E5RJ95|E5RJ95_HUMAN,tr|E5RIC7|E5RIC7_HUMAN,tr|E5RFS0|E5RFS0_HUMAN" 5 927.5178 0.88 3149 14419 2 927.517383 464.7662 DNA topoisomerase 1 OS=Homo sapiens OX=9606 GN=TOP1 PE=1 SV=2 6 3076.6 - 766385 - - - -0.4517 - 1.192 0.213 - 98.2 1 2 0 -0.0004 8 0 0 0 1.54E+07 1.75E+07 - - - 1.1438 0.9996 221125_WJC_METTL3_EV_vs_WT_F01.14422.14422.2 0.000258 16-Jul R.AFSYYGPLR.T "sp|Q16629|SRSF7_HUMAN,tr|C9JAB2|C9JAB2_HUMAN,tr|A0A0B4J1Z1|A0A0B4J1Z1_HUMAN" 3 1072.5342 1.29 3150 14422 2 1072.531873 537.2744 Serine\arginine-rich splicing factor 7 OS=Homo sapiens OX=9606 GN=SRSF7 PE=1 SV=1 8.63 3077 - 6.32E+06 - - - -2.1519 - 1.559 0.533 - 161.8 1 2 0 -0.0023 9 0 0 0 2.87E+08 2.23E+08 - - - 4.2617 0.9257 221125_WJC_METTL3_EV_vs_WT_F01.14423.14423.2 6.45 12-Jun K.LILEYVK[136.11].A "sp|Q7L5N1|CSN6_HUMAN,tr|E7EM64|E7EM64_HUMAN" 2 884.5463 1.06 3151 14423 2 884.544059 443.2804 COP9 signalosome complex subunit 6 OS=Homo sapiens OX=9606 GN=COPS6 PE=1 SV=1 6 3077.1 - 846328 - - - -2.4826 - 1.238 0.038 - 84.1 1 2 0 -0.0022 7 0 0 0 3.28E+07 3.10E+07 - - - -0.0025 0.9995 221125_WJC_METTL3_EV_vs_WT_F01.14424.14424.2 0.00548 20-Nov K.LVLLGESAVGK[136.11].S "sp|P61020|RAB5B_HUMAN,sp|P20339|RAB5A_HUMAN,sp|P51148|RAB5C_HUMAN,tr|F8VVZ0|F8VVZ0_HUMAN,tr|F8VWZ7|F8VWZ7_HUMAN,tr|K7ERI8|K7ERI8_HUMAN,tr|F8VPW9|F8VPW9_HUMAN,tr|F8VSF8|F8VSF8_HUMAN,tr|F8WCY6|F8WCY6_HUMAN,tr|F8WD79|F8WD79_HUMAN,tr|F8VUA5|F8VUA5_HUMAN,tr|K7ERQ8|K7ERQ8_HUMAN,tr|F8VWU4|F8VWU4_HUMAN,tr|F8VVK3|F8VVK3_HUMAN" 14 1092.6634 1.08 3152 14424 2 1092.661479 547.339 Ras-related protein Rab-5B OS=Homo sapiens OX=9606 GN=RAB5B PE=1 SV=1 6 3077.2 - 687234 - - - -1.7682 - 2.35 0.325 - 312.7 1 2 0 -0.0019 11 0 0 0 1.21E+08 1.11E+08 - - - 3.7522 0.8943 221125_WJC_METTL3_EV_vs_WT_F01.14425.14425.2 0.0407 14-Sep R.PIVTVWER[166.11].E "sp|Q96P16|RPR1A_HUMAN,tr|A0A0C4DGQ6|A0A0C4DGQ6_HUMAN,tr|K7EQR8|K7EQR8_HUMAN" 3 1008.5632 1.53 3153 14425 2 1008.560782 505.2889 Regulation of nuclear pre-mRNA domain-containing protein 1A OS=Homo sapiens OX=9606 GN=RPRD1A PE=1 SV=1 6.43 3077.4 - 468477 - - - -2.3836 - 1.678 0.285 - 292.5 1 1 0 -0.0024 8 0 0 0 4.35E+07 2.85E+07 - - - 2.7063 0.9877 221125_WJC_METTL3_EV_vs_WT_F01.14429.14429.2 0.387 12-Aug K.LILEYVK.A "sp|Q7L5N1|CSN6_HUMAN,tr|E7EM64|E7EM64_HUMAN" 2 876.5321 1.08 3155 14429 2 876.533434 439.2733 COP9 signalosome complex subunit 6 OS=Homo sapiens OX=9606 GN=COPS6 PE=1 SV=1 6 3077.8 - 1.01E+06 - - - 1.5732 - 1.205 0.168 - 140.9 1 2 0 0.0014 7 0 0 0 3.53E+07 3.27E+07 - - - 0.8723 0.9989 221125_WJC_METTL3_EV_vs_WT_F01.14433.14433.2 0.476 18-Oct R.INEILSNALK.R "sp|P52272|HNRPM_HUMAN,tr|M0R019|M0R019_HUMAN,tr|A0A087X0X3|A0A087X0X3_HUMAN" 3 1113.6394 1.61 3159 14433 2 1113.637434 557.827 Heterogeneous nuclear ribonucleoprotein M OS=Homo sapiens OX=9606 GN=HNRNPM PE=1 SV=3 6 3078.2 - 278633 - - - -1.742 - 2.016 0.251 - 259.2 1 2 0 -0.0019 10 0 0 0 9.01E+06 5.60E+06 - - - 2.8513 0.9926 221125_WJC_METTL3_EV_vs_WT_F01.14438.14438.2 0.271 12-Jul R.GPIFELK[136.11].S sp|Q9NQS1|AVEN_HUMAN 1 810.4731 1.74 3162 14438 2 810.471715 406.2438 Cell death regulator Aven OS=Homo sapiens OX=9606 GN=AVEN PE=1 SV=1 6 3078.8 - 480369 - - - -1.6965 - 1.302 0.183 - 163 1 2 0 -0.0014 7 0 0 0 1.54E+07 8.87E+06 - - - 1.2284 0.9994 221125_WJC_METTL3_EV_vs_WT_F01.14444.14444.2 0.00561 12-Jul K.YNIMLVR[166.11].L "sp|P50990|TCPQ_HUMAN,tr|H7C4C8|H7C4C8_HUMAN" 2 917.5032 0.34 3165 14444 2 917.501788 459.7589 T-complex protein 1 subunit theta OS=Homo sapiens OX=9606 GN=CCT8 PE=1 SV=4 8.75 3079.6 - 2.56E+07 - - - -1.5695 - 1.551 0.4 - 196.4 1 2 0 -0.0014 7 0 0 0 3.53E+08 1.05E+09 - - - 3.3856 0.9998 221125_WJC_METTL3_EV_vs_WT_F01.14446.14446.2 0.148 13/20 R.MGAGMGFGLER[166.11].M "sp|P52272|HNRPM_HUMAN,tr|M0R2I7|M0R2I7_HUMAN,tr|A0A087X0X3|A0A087X0X3_HUMAN,tr|M0QZM1|M0QZM1_HUMAN" 4 1134.519 1.61 3167 14446 2 1134.518755 568.2668 Heterogeneous nuclear ribonucleoprotein M OS=Homo sapiens OX=9606 GN=HNRNPM PE=1 SV=3 5.75 3079.8 - 958962 - - - -0.1763 - 2.133 0.393 - 593 1 2 0 -0.0002 11 0 0 0 2.36E+08 1.47E+08 - - - 3.9929 0.7673 221125_WJC_METTL3_EV_vs_WT_F01.14451.14451.2 7.74 12-Apr K.LVPGLFK[136.11].N "sp|P35226|BMI1_HUMAN,sp|P35227|PCGF2_HUMAN,tr|Q5T8Z6|Q5T8Z6_HUMAN,tr|A0A087X259|A0A087X259_HUMAN,tr|J3KT13|J3KT13_HUMAN,tr|R4GMX3|R4GMX3_HUMAN,tr|Q5T8Z4|Q5T8Z4_HUMAN" 7 780.4989 0.68 3170 14451 2 780.4967 391.2567 Polycomb complex protein BMI-1 OS=Homo sapiens OX=9606 GN=BMI1 PE=1 SV=2 8.75 3080.5 - 3.52E+06 - - - -2.8328 - 0.983 0.065 - 58.4 2 2 0 -0.0022 7 0 0 0 4.47E+07 6.60E+07 - - - -0.6684 0.8402 221125_WJC_METTL3_EV_vs_WT_F01.14453.14453.2 0.648 12-Jul P.LILEELR[166.11].V "sp|Q9Y467|SALL2_HUMAN,sp|Q9Y592|CEP83_HUMAN,sp|Q96QE3|ATAD5_HUMAN,sp|Q5TFE4|NT5D1_HUMAN,sp|Q9UJ70|NAGK_HUMAN,tr|A0A075B754|A0A075B754_HUMAN,tr|H0YEB7|H0YEB7_HUMAN,tr|C9JEV6|C9JEV6_HUMAN,tr|F5H433|F5H433_HUMAN,tr|H0YE82|H0YE82_HUMAN,tr|H7C3G9|H7C3G9_HUMAN,tr|A0A338VFC5|A0A338VFC5_HUMAN,tr|F8VYN8|F8VYN8_HUMAN,tr|H7C1L7|H7C1L7_HUMAN" 14 894.5414 2.62 3172 14453 2 894.54082 448.278 Sal-like protein 2 OS=Homo sapiens OX=9606 GN=SALL2 PE=1 SV=4 4.53 3080.7 - 868675 - - - -0.635 - 1.454 0.17 - 132.3 1 1 0 -0.0006 7 0 0 0 3.94E+07 1.51E+07 - - - 1.4825 0.9292 221125_WJC_METTL3_EV_vs_WT_F01.14454.14454.2 0.617 14-Sep R.PFTLGQLK.E "sp|Q9UKV3|ACINU_HUMAN,tr|G3V3B0|G3V3B0_HUMAN,tr|S4R3H4|S4R3H4_HUMAN,tr|E7EQT4|E7EQT4_HUMAN" 4 902.5226 1.24 3173 14454 2 902.521565 452.2686 Apoptotic chromatin condensation inducer in the nucleus OS=Homo sapiens OX=9606 GN=ACIN1 PE=1 SV=2 9.18 3080.9 - 648107 - - - -1.0947 - 1.624 0.251 - 228.6 1 1 0 -0.001 8 0 0 0 1.84E+07 1.48E+07 - - - 2.357 0.9981 221125_WJC_METTL3_EV_vs_WT_F01.14458.14458.2 0.00822 22-Jun K.FAQALGLTEAVK[136.11].V "sp|P78347|GTF2I_HUMAN,tr|A0A494C1K3|A0A494C1K3_HUMAN" 2 1254.7063 2.32 3177 14458 2 1254.705401 628.3604 General transcription factor II-I OS=Homo sapiens OX=9606 GN=GTF2I PE=1 SV=2 6 3081.4 - 160729 - - - -0.7468 - 1.226 0.316 - 77.9 1 2 0 -0.0009 12 0 0 0 3.20E+06 1.38E+06 - - - 1.9108 0.9942 221125_WJC_METTL3_EV_vs_WT_F01.14462.14462.2 0.0536 20-Aug K.LIPGPLSPVAR[166.11].G sp|P48634|PRC2A_HUMAN 1 1128.6894 -1 3180 14462 2 1128.68914 565.352 Protein PRRC2A OS=Homo sapiens OX=9606 GN=PRRC2A PE=1 SV=3 9.75 3081.7 - 1.49E+06 - - - -0.2738 - 1.384 0.146 - 107.2 1 2 0 -0.0003 11 0 0 0 0.00E+00 0.00E+00 - - - 0.9984 0.9983 221125_WJC_METTL3_EV_vs_WT_F01.14463.14463.2 0.0231 16-Aug K.YLPELMAEK[136.11].D "sp|Q5VWX1|KHDR2_HUMAN,sp|Q07666|KHDR1_HUMAN,sp|O75525|KHDR3_HUMAN,tr|A0A6Q8PGH5|A0A6Q8PGH5_HUMAN" 4 1100.5667 0.98 3181 14463 2 1100.56564 551.2906 "KH domain-containing, RNA-binding, signal transduction-associated protein 2 OS=Homo sapiens OX=9606 GN=KHDRBS2 PE=1 SV=1" 4.53 3081.8 - 1.01E+06 - - - -0.9931 - 1.3 0.305 - 177.3 1 2 0 -0.0011 9 0 0 0 1.25E+08 1.28E+08 - - - 2.0524 0.9975 221125_WJC_METTL3_EV_vs_WT_F01.14464.14464.2 0.0272 14-Jul K.LIYLVPEK.Q "sp|Q9NZM3|ITSN2_HUMAN,tr|A0A087WVF7|A0A087WVF7_HUMAN,tr|E7EPJ2|E7EPJ2_HUMAN" 3 973.5848 3.03 3182 14464 2 973.585447 487.7997 Intersectin-2 OS=Homo sapiens OX=9606 GN=ITSN2 PE=1 SV=3 6 3081.9 - 930541 - - - 0.645 - 1.304 0.256 - 152 1 2 0 0.0006 8 0 0 0 4.31E+07 1.42E+07 - - - 1.7322 0.9981 221125_WJC_METTL3_EV_vs_WT_F01.14465.14465.2 0.0374 16-Aug R.ILDSAEFIK.F "sp|P78347|GTF2I_HUMAN,tr|A0A494C1K3|A0A494C1K3_HUMAN" 2 1034.5648 0.87 3183 14465 2 1034.564237 518.2897 General transcription factor II-I OS=Homo sapiens OX=9606 GN=GTF2I PE=1 SV=2 4.37 3082 - 1.33E+06 - - - -0.5558 - 1.315 0.274 - 130.2 1 2 0 -0.0006 9 0 0 0 1.29E+06 1.49E+06 - - - 1.8568 0.9527 221125_WJC_METTL3_EV_vs_WT_F01.14470.14470.2 1.24 14-Apr K.LTPLLSVR.E "sp|Q9BXP5|SRRT_HUMAN,tr|H7C3A1|H7C3A1_HUMAN" 2 897.5648 0.81 3186 14470 2 897.564767 449.7897 Serrate RNA effector molecule homolog OS=Homo sapiens OX=9606 GN=SRRT PE=1 SV=1 9.75 3082.6 - 515477 - - - 0.0156 - 1.017 0.129 - 45.2 10 2 0 0 8 0 0 0 3.03E+06 3.76E+06 - - - -0.4021 0.9997 221125_WJC_METTL3_EV_vs_WT_F01.14471.14471.2 0.0157 14-Oct R.YADLLLEK.E sp|Q99459|CDC5L_HUMAN 1 963.5277 0.65 3187 14471 2 963.526558 482.7711 Cell division cycle 5-like protein OS=Homo sapiens OX=9606 GN=CDC5L PE=1 SV=2 4.37 3082.7 - 947580 - - - -1.1832 - 1.906 0.386 - 251.3 1 2 0 -0.0011 8 0 0 0 4.68E+06 7.15E+06 - - - 3.8369 0.9987 221125_WJC_METTL3_EV_vs_WT_F01.14472.14472.2 0.0747 20-Aug K.LIPGPLSPVAR.G sp|P48634|PRC2A_HUMAN 1 1118.6812 -1 3188 14472 2 1118.680757 560.3479 Protein PRRC2A OS=Homo sapiens OX=9606 GN=PRRC2A PE=1 SV=3 9.75 3082.8 - 2.26E+06 - - - -0.3772 - 1.577 0.257 - 267.2 1 2 0 -0.0004 11 0 0 0 0.00E+00 0.00E+00 - - - 2.1714 0.9997 221125_WJC_METTL3_EV_vs_WT_F01.14473.14473.2 0.0385 16-Sep R.ILDSAEFIK[136.11].F "sp|P78347|GTF2I_HUMAN,tr|A0A494C1K3|A0A494C1K3_HUMAN" 2 1042.579 1.46 3189 14473 2 1042.578808 522.2968 General transcription factor II-I OS=Homo sapiens OX=9606 GN=GTF2I PE=1 SV=2 4.37 3082.9 - 1.75E+06 - - - -0.1957 - 1.812 0.37 - 162.9 1 2 0 -0.0002 9 0 0 0 3.80E+09 2.59E+09 - - - 3.4935 0.993 221125_WJC_METTL3_EV_vs_WT_F01.14478.14478.2 0.214 16-Sep K.TLAIELAPR[166.11].N "sp|P0CG22|DR4L1_HUMAN,sp|Q6PKH6|DR4L2_HUMAN,sp|Q9BTZ2|DHRS4_HUMAN,tr|A0A087WSZ6|A0A087WSZ6_HUMAN,tr|F6TD35|F6TD35_HUMAN,tr|F6VUV4|F6VUV4_HUMAN,tr|A0A087WXI8|A0A087WXI8_HUMAN,tr|H0YKN3|H0YKN3_HUMAN" 8 992.5894 1 3194 14478 2 992.593876 497.302 Putative dehydrogenase\reductase SDR family member 4-like 1 OS=Homo sapiens OX=9606 GN=DHRS4L1 PE=5 SV=1 5.66 3083.5 - 243722 - - - 4.5084 - 1.806 0.305 - 210.8 1 2 0 0.0045 9 0 0 0 1.67E+06 1.67E+06 - - - 3.0025 0.9772 221125_WJC_METTL3_EV_vs_WT_F01.14480.14480.2 0.582 12-Jul R.AVTIFIR[166.11].G "sp|P48643|TCPE_HUMAN,sp|Q6ZVL6|K154L_HUMAN,tr|E9PCA1|E9PCA1_HUMAN,tr|B7ZAR1|B7ZAR1_HUMAN,tr|E7ENZ3|E7ENZ3_HUMAN,tr|H0YDE5|H0YDE5_HUMAN,tr|A0A590UJI0|A0A590UJI0_HUMAN,tr|A0A5F9UK30|A0A5F9UK30_HUMAN" 8 828.5097 0.59 3195 14480 2 828.509606 415.2621 T-complex protein 1 subunit epsilon OS=Homo sapiens OX=9606 GN=CCT5 PE=1 SV=1 9.79 3083.7 - 3.01E+06 - - - -0.1062 - 1.357 0.026 - 210.5 2 2 0 -0.0001 7 0 0 0 4.93E+07 8.31E+07 - - - 0.0658 0.9901 221125_WJC_METTL3_EV_vs_WT_F01.14481.14481.2 4.97 12-Jun R.AVTIFIR.G "sp|P48643|TCPE_HUMAN,sp|Q6ZVL6|K154L_HUMAN,tr|E9PCA1|E9PCA1_HUMAN,tr|B7ZAR1|B7ZAR1_HUMAN,tr|E7ENZ3|E7ENZ3_HUMAN,tr|H0YDE5|H0YDE5_HUMAN,tr|A0A590UJI0|A0A590UJI0_HUMAN,tr|A0A5F9UK30|A0A5F9UK30_HUMAN" 8 818.5014 0.55 3196 14481 2 818.501232 410.258 T-complex protein 1 subunit epsilon OS=Homo sapiens OX=9606 GN=CCT5 PE=1 SV=1 9.79 3083.8 - 1.48E+06 - - - -0.2346 - 1.246 0.12 - 139.1 1 2 0 -0.0002 7 0 0 0 6.70E+07 1.22E+08 - - - 0.6241 0.9354 221125_WJC_METTL3_EV_vs_WT_F01.14482.14482.2 4.55 14-May K.IEPPGLFR[166.11].G "sp|P11387|TOP1_HUMAN,sp|Q969P6|TOP1M_HUMAN,tr|E5RJ95|E5RJ95_HUMAN,tr|E5RIC7|E5RIC7_HUMAN,tr|E5RFS0|E5RFS0_HUMAN" 5 937.5261 0.63 3197 14482 2 937.526623 469.7703 DNA topoisomerase 1 OS=Homo sapiens OX=9606 GN=TOP1 PE=1 SV=2 6 3083.8 - 2.16E+06 - - - 0.5877 - 0.995 0.096 - 87 4 2 0 0.0006 8 0 0 0 5.25E+07 8.30E+07 - - - -0.5342 0.995 221125_WJC_METTL3_EV_vs_WT_F01.14483.14483.2 0.0313 14-Aug R.DAFVYAIK.N "sp|Q9HD45|TM9S3_HUMAN,tr|Q5TB53|Q5TB53_HUMAN" 2 925.4909 1.19 3198 14483 2 925.491318 463.7527 Transmembrane 9 superfamily member 3 OS=Homo sapiens OX=9606 GN=TM9SF3 PE=1 SV=2 5.83 3083.9 - 1.85E+06 - - - 0.4311 - 1.364 0.158 - 253.4 1 2 0 0.0004 8 0 0 0 1.45E+08 1.22E+08 - - - 1.1441 0.9935 221125_WJC_METTL3_EV_vs_WT_F01.14484.14484.2 0.197 12-Jun R.QMSLLLR.R sp|P25705|ATPA_HUMAN 1 859.495 1.42 3199 14484 2 859.494309 430.7548 "ATP synthase subunit alpha, mitochondrial OS=Homo sapiens OX=9606 GN=ATP5F1A PE=1 SV=1" 9.75 3084 - 1.61E+06 - - - -0.7551 - 1.381 0.124 - 225.3 1 2 0 -0.0006 7 0 0 0 3.73E+08 2.63E+08 - - - 0.9795 0.9952 221125_WJC_METTL3_EV_vs_WT_F01.14485.14485.2 0.132 12-Jul R.QMSLLLR[166.11].R sp|P25705|ATPA_HUMAN 1 869.5032 1.44 3200 14485 2 869.503474 435.7589 "ATP synthase subunit alpha, mitochondrial OS=Homo sapiens OX=9606 GN=ATP5F1A PE=1 SV=1" 9.75 3084 - 1.59E+06 - - - 0.2829 - 1.524 0.106 - 197.5 1 2 0 0.0002 7 0 0 0 3.69E+08 2.57E+08 - - - 1.1589 0.993 221125_WJC_METTL3_EV_vs_WT_F01.14487.14487.2 20.4 12-Aug K.IGIEIIK[136.11].R "sp|P10809|CH60_HUMAN,tr|A0A7I2V2X6|A0A7I2V2X6_HUMAN,tr|A0A7I2YQK6|A0A7I2YQK6_HUMAN,tr|A0A7I2V599|A0A7I2V599_HUMAN" 4 792.52 91.68 3202 14487 2 792.519171 397.2673 "60 kDa heat shock protein, mitochondrial OS=Homo sapiens OX=9606 GN=HSPD1 PE=1 SV=2" 6 3084.2 - 823115 - - - -1.0978 - 1.523 0.088 - 155.4 1 2 0 -0.0009 7 0 0 0 4.93E+09 5.38E+07 - - - 1.0236 0.9957 221125_WJC_METTL3_EV_vs_WT_F01.14489.14489.2 0.103 12-Jul R.LNLYELK[136.11].E "sp|P49720|PSB3_HUMAN,tr|A0A087WXQ8|A0A087WXQ8_HUMAN,tr|A0A087WUL2|A0A087WUL2_HUMAN,tr|A0A087WY10|A0A087WY10_HUMAN" 4 899.5208 0.75 3204 14489 2 899.522132 450.7677 Proteasome subunit beta type-3 OS=Homo sapiens OX=9606 GN=PSMB3 PE=1 SV=2 6 3084.4 - 501946 - - - 1.5153 - 1.547 0.161 - 152.8 1 2 0 0.0014 7 0 0 0 5.27E+07 7.02E+07 - - - 1.6122 0.9815 221125_WJC_METTL3_EV_vs_WT_F01.14490.14490.2 2.45 12-Jun K.MILTFEK[136.11].R "sp|Q8WYA6|CTBL1_HUMAN,tr|A0A087WUB9|A0A087WUB9_HUMAN,tr|A2A2P1|A2A2P1_HUMAN" 3 888.487 0.35 3205 14490 2 888.487379 445.2508 Beta-catenin-like protein 1 OS=Homo sapiens OX=9606 GN=CTNNBL1 PE=1 SV=1 5.75 3084.5 - 526062 - - - 0.3973 - 1.212 0.081 - 103.5 1 2 0 0.0004 7 0 0 0 4.72E+06 1.34E+07 - - - 0.2484 1 221125_WJC_METTL3_EV_vs_WT_F01.14493.14493.2 1.12E-05 13/20 R.MGAGMGFGLER.M "sp|P52272|HNRPM_HUMAN,tr|M0R2I7|M0R2I7_HUMAN,tr|A0A087X0X3|A0A087X0X3_HUMAN,tr|M0QZM1|M0QZM1_HUMAN" 4 1124.5107 1.61 3207 14493 2 1124.510646 563.2626 Heterogeneous nuclear ribonucleoprotein M OS=Homo sapiens OX=9606 GN=HNRNPM PE=1 SV=3 5.75 3084.9 - 9.23E+06 - - - -0.0347 - 2.776 0.598 - 800.9 1 2 0 0 11 0 0 0 2.36E+08 1.47E+08 - - - 6.2199 0.9995 221125_WJC_METTL3_EV_vs_WT_F01.14495.14495.2 0.0535 20-Oct K.LVLLGESAVGK.S "sp|P61020|RAB5B_HUMAN,sp|P20339|RAB5A_HUMAN,sp|P51148|RAB5C_HUMAN,tr|F8VVZ0|F8VVZ0_HUMAN,tr|F8VWZ7|F8VWZ7_HUMAN,tr|K7ERI8|K7ERI8_HUMAN,tr|F8VPW9|F8VPW9_HUMAN,tr|F8VSF8|F8VSF8_HUMAN,tr|F8WCY6|F8WCY6_HUMAN,tr|F8WD79|F8WD79_HUMAN,tr|F8VUA5|F8VUA5_HUMAN,tr|K7ERQ8|K7ERQ8_HUMAN,tr|F8VWU4|F8VWU4_HUMAN,tr|F8VVK3|F8VVK3_HUMAN" 14 1084.6492 1.08 3208 14495 2 1084.649062 543.3319 Ras-related protein Rab-5B OS=Homo sapiens OX=9606 GN=RAB5B PE=1 SV=1 6 3085.1 - 5.72E+06 - - - -0.1374 - 2.067 0.263 - 308.1 1 2 0 -0.0001 11 0 0 0 1.21E+08 1.11E+08 - - - 2.9477 0.9887 221125_WJC_METTL3_EV_vs_WT_F01.14497.14497.2 0.00795 14-Aug R.DAFVYAIK[136.11].N "sp|Q9HD45|TM9S3_HUMAN,tr|Q5TB53|Q5TB53_HUMAN" 2 933.5051 1.19 3210 14497 2 933.50095 467.7598 Transmembrane 9 superfamily member 3 OS=Homo sapiens OX=9606 GN=TM9SF3 PE=1 SV=2 5.83 3085.3 - 2.31E+06 - - - -4.466 - 1.615 0.272 - 240.4 1 2 0 -0.0042 8 0 0 0 1.45E+08 1.22E+08 - - - 2.4943 0.9998 221125_WJC_METTL3_EV_vs_WT_F01.14500.14500.2 8.44E-05 20-Sep R.FGSLTMDGGLR.N "sp|Q9UHD2|TBK1_HUMAN,tr|A0A7I2V646|A0A7I2V646_HUMAN,tr|A0A7I2V4W4|A0A7I2V4W4_HUMAN,tr|A0A494C148|A0A494C148_HUMAN,tr|A0A494C0X2|A0A494C0X2_HUMAN,tr|A0A494C167|A0A494C167_HUMAN,tr|A0A7I2V2F4|A0A7I2V2F4_HUMAN,tr|A0A7I2V643|A0A7I2V643_HUMAN" 8 1152.5597 2.41 3213 14500 2 1152.558166 577.2871 Serine\threonine-protein kinase TBK1 OS=Homo sapiens OX=9606 GN=TBK1 PE=1 SV=1 5.84 3085.6 - 117455 - - - -1.3691 - 2.034 0.516 - 263.5 1 2 0 -0.0016 11 0 0 0 3.64E+06 1.51E+06 - - - 4.7724 0.9998 221125_WJC_METTL3_EV_vs_WT_F01.14503.14503.2 0.000545 14-Sep R.VGEIVVFR.L "sp|P67812|SC11A_HUMAN,tr|H0YNA5|H0YNA5_HUMAN,tr|H0YNG3|H0YNG3_HUMAN,tr|H0YNX5|H0YNX5_HUMAN" 4 917.5335 1.99 3214 14503 2 917.534263 459.774 Signal peptidase complex catalytic subunit SEC11A OS=Homo sapiens OX=9606 GN=SEC11A PE=1 SV=1 5.97 3086.1 - 960225 - - - 0.8839 - 1.998 0.43 - 389 1 2 0 0.0008 8 0 0 0 8.93E+07 4.50E+07 - - - 4.3042 0.9995 221125_WJC_METTL3_EV_vs_WT_F01.14505.14505.2 0.00191 16-Sep K.YLPELMAEK.D "sp|Q5VWX1|KHDR2_HUMAN,sp|Q07666|KHDR1_HUMAN,sp|O75525|KHDR3_HUMAN,tr|A0A6Q8PGH5|A0A6Q8PGH5_HUMAN" 4 1092.5525 0.97 3216 14505 2 1092.553077 547.2835 "KH domain-containing, RNA-binding, signal transduction-associated protein 2 OS=Homo sapiens OX=9606 GN=KHDRBS2 PE=1 SV=1" 4.53 3086.2 - 4.00E+06 - - - 0.4979 - 1.417 0.419 - 250.1 1 2 0 0.0005 9 0 0 0 1.25E+08 1.28E+08 - - - 3.1439 0.9996 221125_WJC_METTL3_EV_vs_WT_F01.14506.14506.2 0.039 18-Oct R.ILALEADMTK[136.11].W "sp|Q4VCS5|AMOT_HUMAN,sp|Q9Y2J4|AMOL2_HUMAN,sp|Q8IY63|AMOL1_HUMAN,tr|A6NP16|A6NP16_HUMAN,tr|E7ERM3|E7ERM3_HUMAN" 5 1111.6038 1.62 3217 14506 2 1111.603771 556.8092 Angiomotin OS=Homo sapiens OX=9606 GN=AMOT PE=1 SV=1 4.37 3086.4 - 228469 - - - -0.0684 - 1.874 0.341 - 226.3 1 2 0 -0.0001 10 0 0 0 3.32E+07 2.06E+07 - - - 3.3128 0.9992 221125_WJC_METTL3_EV_vs_WT_F01.14510.14510.2 0.00919 14-Aug K.LIYLVPEK[136.11].Q "sp|Q9NZM3|ITSN2_HUMAN,tr|A0A087WVF7|A0A087WVF7_HUMAN,tr|E7EPJ2|E7EPJ2_HUMAN" 3 981.599 3.04 3219 14510 2 981.600253 491.8068 Intersectin-2 OS=Homo sapiens OX=9606 GN=ITSN2 PE=1 SV=3 6 3086.9 - 631121 - - - 1.2571 - 1.419 0.392 - 169.1 1 2 0 0.0012 8 0 0 0 4.41E+07 1.45E+07 - - - 2.9914 0.9994 221125_WJC_METTL3_EV_vs_WT_F01.14511.14511.2 0.000168 18-Aug R.FLIC[160.03]TDVAAR[166.11].G "sp|Q92499|DDX1_HUMAN,tr|A0A7I2V2M5|A0A7I2V2M5_HUMAN,tr|A0A087X2G1|A0A087X2G1_HUMAN,tr|A0A7I2V430|A0A7I2V430_HUMAN,tr|A0A7I2V4F0|A0A7I2V4F0_HUMAN,tr|A0A087WZ71|A0A087WZ71_HUMAN" 6 1174.6044 1.44 3220 14511 2 1174.602025 588.3095 ATP-dependent RNA helicase DDX1 OS=Homo sapiens OX=9606 GN=DDX1 PE=1 SV=2 5.83 3087 - 263047 - - - -2.0211 - 1.606 0.46 - 254.4 1 2 0 -0.0024 10 0 0 0 3.39E+07 2.35E+07 - - - 3.7602 0.8356 221125_WJC_METTL3_EV_vs_WT_F01.14542.14542.2 8.28 14-Jun K.EALVSAAK[136.11].L "sp|Q7Z6B0|CCD91_HUMAN,tr|F5GZH9|F5GZH9_HUMAN,tr|A0A0A0MTK0|A0A0A0MTK0_HUMAN,tr|A0A0A0MTP0|A0A0A0MTP0_HUMAN,tr|F5GWR1|F5GWR1_HUMAN" 5 795.4582 0.33 3238 14542 2 795.456233 398.7364 Coiled-coil domain-containing protein 91 OS=Homo sapiens OX=9606 GN=CCDC91 PE=1 SV=2 6.1 3090.9 - 487870 - - - -2.4338 - 1.081 0.048 - 66.5 3 2 0 -0.0019 8 0 0 0 4.24E+06 1.30E+07 - - - -0.5833 0.9985 221125_WJC_METTL3_EV_vs_WT_F01.14543.14543.2 0.178 16-Aug K.ILTLTYVDK[136.11].L sp|P08240|SRPRA_HUMAN 1 1072.626 2.07 3239 14543 2 1072.625448 537.3203 Signal recognition particle receptor subunit alpha OS=Homo sapiens OX=9606 GN=SRPRA PE=1 SV=2 5.83 3091.1 - 294244 - - - -0.4792 - 1.394 0.274 - 156.3 1 2 0 -0.0005 9 0 0 0 2.20E+07 1.06E+07 - - - 2.0256 0.9936 221125_WJC_METTL3_EV_vs_WT_F01.14549.14549.3 0.0355 Nov-44 R.YLYTLVITDKEK.A "sp|P63173|RL38_HUMAN,tr|J3KT73|J3KT73_HUMAN,tr|J3QL01|J3QL01_HUMAN" 3 1484.8126 1.31 3243 14549 3 1484.810884 495.9448 60S ribosomal protein L38 OS=Homo sapiens OX=9606 GN=RPL38 PE=1 SV=2 6.07 3091.8 - 715713 - - - -1.1874 - 1.718 0.278 - 86.4 1 2 1 -0.0018 12 0 0 0 1.77E+07 1.35E+07 - - - 3.139 0.9994 221125_WJC_METTL3_EV_vs_WT_F01.14557.14557.2 0.0715 14-Jul K.FLVGFTNK[136.11].G "sp|P43307|SSRA_HUMAN,tr|A0A3B3IRT8|A0A3B3IRT8_HUMAN,tr|E9PAL7|E9PAL7_HUMAN,tr|C9IZQ1|C9IZQ1_HUMAN,tr|C9J3L8|C9J3L8_HUMAN,tr|C9J5W0|C9J5W0_HUMAN" 6 932.5211 1.38 3249 14557 2 932.521239 467.2678 Translocon-associated protein subunit alpha OS=Homo sapiens OX=9606 GN=SSR1 PE=1 SV=3 8.75 3092.9 - 6.24E+06 - - - 0.1458 - 1.521 0.355 - 129.3 1 2 0 0.0001 8 0 0 0 2.77E+08 2.00E+08 - - - 2.9278 0.9991 221125_WJC_METTL3_EV_vs_WT_F01.14558.14558.2 0.061 12-Jul R.FLTVMMK[136.11].H "sp|P62244|RS15A_HUMAN,tr|I3L246|I3L246_HUMAN,tr|I3L3P7|I3L3P7_HUMAN,tr|I3L303|I3L303_HUMAN,tr|H3BT37|H3BT37_HUMAN,tr|H3BV27|H3BV27_HUMAN,tr|H3BN98|H3BN98_HUMAN" 7 876.4693 0.87 3250 14558 2 876.467885 439.2419 40S ribosomal protein S15a OS=Homo sapiens OX=9606 GN=RPS15A PE=1 SV=2 8.75 3092.9 - 2.13E+06 - - - -1.5768 - 1.479 0.362 - 158.5 1 2 0 -0.0014 7 0 0 0 1.53E+08 1.75E+08 - - - 2.9544 0.9984 221125_WJC_METTL3_EV_vs_WT_F01.14560.14560.2 0.0869 14-Sep R.LLEIVSYK[136.11].L "sp|Q93009|UBP7_HUMAN,tr|A0A669KBL1|A0A669KBL1_HUMAN,tr|H3BND8|H3BND8_HUMAN" 3 971.5783 1 3252 14560 2 971.57826 486.7964 Ubiquitin carboxyl-terminal hydrolase 7 OS=Homo sapiens OX=9606 GN=USP7 PE=1 SV=2 6 3093.1 - 793804 - - - -0.0247 - 1.453 0.241 - 220.2 1 2 0 0 8 0 0 0 1.33E+08 1.34E+08 - - - 1.9479 0.9982 221125_WJC_METTL3_EV_vs_WT_F01.14566.14566.2 0.0657 14-Sep K.FLVGFTNK.G "sp|P43307|SSRA_HUMAN,tr|A0A3B3IRT8|A0A3B3IRT8_HUMAN,tr|E9PAL7|E9PAL7_HUMAN,tr|C9IZQ1|C9IZQ1_HUMAN,tr|C9J3L8|C9J3L8_HUMAN,tr|C9J5W0|C9J5W0_HUMAN" 6 924.5069 1.38 3256 14566 2 924.506647 463.2607 Translocon-associated protein subunit alpha OS=Homo sapiens OX=9606 GN=SSR1 PE=1 SV=3 8.75 3093.8 - 9.74E+06 - - - -0.2769 - 1.541 0.204 - 255.5 1 2 0 -0.0003 8 0 0 0 2.77E+08 2.01E+08 - - - 1.8519 0.9996 221125_WJC_METTL3_EV_vs_WT_F01.14569.14569.2 0.00545 14-Jul R.EIGMWYAK.K sp|Q9H2U1|DHX36_HUMAN 1 996.4739 0.98 3259 14569 2 996.473393 499.2442 ATP-dependent DNA\RNA helicase DHX36 OS=Homo sapiens OX=9606 GN=DHX36 PE=1 SV=2 6.1 3094.1 - 866898 - - - -0.4978 - 1.316 0.452 - 178.3 1 2 0 -0.0005 8 0 0 0 2.51E+07 2.57E+07 - - - 3.2075 0.9997 221125_WJC_METTL3_EV_vs_WT_F01.14571.14571.2 0.00175 22-Aug K.LIVTSATLDAVK[136.11].F "sp|Q14562|DHX8_HUMAN,tr|F5H658|F5H658_HUMAN" 2 1237.7373 1.27 3261 14571 2 1237.73594 619.8759 ATP-dependent RNA helicase DHX8 OS=Homo sapiens OX=9606 GN=DHX8 PE=1 SV=1 5.84 3094.3 - 176277 - - - -1.102 - 1.78 0.467 - 139.6 1 2 0 -0.0014 12 0 0 0 5.26E+06 4.14E+06 - - - 4.007 0.9998 221125_WJC_METTL3_EV_vs_WT_F01.14575.14575.2 0.000484 18-Oct R.ILALEADMTK.W "sp|Q4VCS5|AMOT_HUMAN,sp|Q9Y2J4|AMOL2_HUMAN,sp|Q8IY63|AMOL1_HUMAN,tr|A6NP16|A6NP16_HUMAN,tr|E7ERM3|E7ERM3_HUMAN" 5 1103.5896 1.57 3263 14575 2 1103.590078 552.8021 Angiomotin OS=Homo sapiens OX=9606 GN=AMOT PE=1 SV=1 4.37 3094.9 - 698317 - - - 0.3905 - 1.992 0.396 - 249.6 1 2 0 0.0004 10 0 0 0 3.32E+07 2.11E+07 - - - 3.8893 0.9894 221125_WJC_METTL3_EV_vs_WT_F01.14576.14576.2 4.27E-06 Dec-34 K.PSTASAVPELATDPELEK[136.11].K "sp|Q86U44|MTA70_HUMAN,tr|B4E349|B4E349_HUMAN,tr|F5H6D8|F5H6D8_HUMAN,tr|H0YFV6|H0YFV6_HUMAN,tr|B4DTN4|B4DTN4_HUMAN" 5 1861.94 0.01 3264 14576 2 1861.93835 931.9773 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 4 3095 - 196220 - - - -0.9071 - 2.07 0.49 - 184.2 1 1 0 -0.0017 18 0 0 0 5.52E+04 6.16E+06 - - - 4.4483 0.8362 221125_WJC_METTL3_EV_vs_WT_F01.14586.14586.2 1.03 12-Sep Q.IGELILK.R "sp|Q9HCG8|CWC22_HUMAN,tr|B7WP74|B7WP74_HUMAN" 2 784.5058 1.95 3270 14586 2 784.505715 393.2602 Pre-mRNA-splicing factor CWC22 homolog OS=Homo sapiens OX=9606 GN=CWC22 PE=1 SV=3 6 3096.2 - 9.10E+06 - - - -0.1606 - 1.8 0.069 - 209.1 1 1 0 -0.0001 7 0 0 0 8.33E+07 4.26E+07 - - - 1.413 0.9934 221125_WJC_METTL3_EV_vs_WT_F01.14591.14591.2 0.604 16-Jul K.MLLYTEVTR[166.11].Y "sp|P31150|GDIA_HUMAN,sp|P50395|GDIB_HUMAN,tr|G5E9U5|G5E9U5_HUMAN,tr|Q5SX86|Q5SX86_HUMAN,tr|Q5SX90|Q5SX90_HUMAN,tr|V9GYF8|V9GYF8_HUMAN,tr|V9GYJ7|V9GYJ7_HUMAN" 7 1134.5983 1.57 3273 14591 2 1134.596959 568.3064 Rab GDP dissociation inhibitor alpha OS=Homo sapiens OX=9606 GN=GDI1 PE=1 SV=2 5.75 3096.8 - 455017 - - - -1.1387 - 1.384 0.149 - 183.2 1 2 0 -0.0013 9 0 0 0 5.16E+07 3.28E+07 - - - 1.0813 0.9996 221125_WJC_METTL3_EV_vs_WT_F01.14592.14592.2 0.00157 16-Aug K.ANPALYVLR.E sp|Q6P2Q9|PRP8_HUMAN 1 1015.5815 999 3274 14592 2 1015.582515 508.798 Pre-mRNA-processing-splicing factor 8 OS=Homo sapiens OX=9606 GN=PRPF8 PE=1 SV=2 8.79 3096.9 - 2.27E+06 - - - 1.0339 - 1.841 0.368 - 450.9 1 2 0 0.001 9 0 0 0 1.29E+08 0.00E+00 - - - 3.5244 0.9986 221125_WJC_METTL3_EV_vs_WT_F01.14597.14597.2 0.91 12-Aug R.FAVFIEK.V sp|Q16352|AINX_HUMAN 1 852.4745 0.96 3277 14597 2 852.474495 427.2445 Alpha-internexin OS=Homo sapiens OX=9606 GN=INA PE=1 SV=2 6 3097.5 - 2.26E+06 - - - -0.054 - 1.805 0.159 - 205 1 2 0 0 7 0 0 0 1.94E+08 2.01E+08 - - - 2.0866 0.9979 221125_WJC_METTL3_EV_vs_WT_F01.14601.14601.2 0.232 12-Aug K.MDLLLTK.T "sp|Q6P3W7|SCYL2_HUMAN,tr|H0YIK6|H0YIK6_HUMAN,tr|F8VSC5|F8VSC5_HUMAN,tr|A0A0U1RQQ9|A0A0U1RQQ9_HUMAN" 4 832.4728 3.01 3279 14601 2 832.471878 417.2437 SCY1-like protein 2 OS=Homo sapiens OX=9606 GN=SCYL2 PE=1 SV=1 5.59 3098 - 4.13E+06 - - - -1.1388 - 1.58 0.195 - 270.1 1 2 0 -0.0009 7 0 0 0 1.98E+08 6.56E+07 - - - 1.9303 0.9995 221125_WJC_METTL3_EV_vs_WT_F01.14603.14603.2 1.32E-05 20-Dec K.LVGDVDFEGVR[166.11].Q "sp|P13995|MTDC_HUMAN,tr|A0A7I2V482|A0A7I2V482_HUMAN,tr|A0A7I2V2U6|A0A7I2V2U6_HUMAN,tr|B9A062|B9A062_HUMAN" 4 1214.6171 1.31 3280 14603 2 1214.620811 608.3158 "Bifunctional methylenetetrahydrofolate dehydrogenase\cyclohydrolase, mitochondrial OS=Homo sapiens OX=9606 GN=MTHFD2 PE=1 SV=2" 4.03 3098.2 - 629925 - - - 3.0783 - 2.148 0.529 - 444.2 1 2 0 0.0037 11 0 0 0 6.16E+07 4.71E+07 - - - 5.0153 0.9981 221125_WJC_METTL3_EV_vs_WT_F01.14605.14605.2 0.00882 12-Aug R.FLTVMMK.H "sp|P62244|RS15A_HUMAN,tr|I3L246|I3L246_HUMAN,tr|I3L3P7|I3L3P7_HUMAN,tr|I3L303|I3L303_HUMAN,tr|H3BT37|H3BT37_HUMAN,tr|H3BV27|H3BV27_HUMAN,tr|H3BN98|H3BN98_HUMAN" 7 868.4551 0.87 3282 14605 2 868.454802 435.2348 40S ribosomal protein S15a OS=Homo sapiens OX=9606 GN=RPS15A PE=1 SV=2 8.75 3098.4 - 5.57E+06 - - - -0.3051 - 1.285 0.27 - 180.1 1 2 0 -0.0003 7 0 0 0 1.53E+08 1.75E+08 - - - 1.8297 0.9921 221125_WJC_METTL3_EV_vs_WT_F01.14611.14611.2 1.91 14-Aug K.LLIESLEK[136.11].Y "sp|Q8TC07|TBC15_HUMAN,tr|F8VV61|F8VV61_HUMAN,tr|C9JA93|C9JA93_HUMAN" 3 951.5732 0.67 3286 14611 2 951.5727 476.7939 TBC1 domain family member 15 OS=Homo sapiens OX=9606 GN=TBC1D15 PE=1 SV=2 4.53 3099.1 - 1.09E+06 - - - -0.5244 - 1.234 0.152 - 144.7 1 2 0 -0.0005 8 0 0 0 1.84E+07 2.74E+07 - - - 0.7977 0.9997 221125_WJC_METTL3_EV_vs_WT_F01.14612.14612.2 1.34E-05 16-Oct R.AFGYYGPLR[166.11].S "sp|P84103|SRSF3_HUMAN,tr|A0A087X2D0|A0A087X2D0_HUMAN" 2 1052.5319 1.21 3287 14612 2 1052.530332 527.2732 Serine\arginine-rich splicing factor 3 OS=Homo sapiens OX=9606 GN=SRSF3 PE=1 SV=1 8.63 3099.2 - 1.07E+06 - - - -1.4764 - 1.998 0.44 - 371.7 1 2 0 -0.0016 9 0 0 0 1.53E+09 1.26E+09 - - - 4.2928 0.9983 221125_WJC_METTL3_EV_vs_WT_F01.14616.14616.2 0.0825 16-Sep R.LLGYVATLK.D "sp|O75534|CSDE1_HUMAN,tr|E9PLT0|E9PLT0_HUMAN" 2 976.5957 0.49 3289 14616 2 976.594338 489.3051 Cold shock domain-containing protein E1 OS=Homo sapiens OX=9606 GN=CSDE1 PE=1 SV=2 8.59 3099.7 - 3.50E+06 - - - -1.4131 - 1.435 0.291 - 166.7 1 2 0 -0.0014 9 0 0 0 1.00E+08 2.05E+08 - - - 2.2348 0.9933 221125_WJC_METTL3_EV_vs_WT_F01.14617.14617.2 0.0416 14-Jun K.NVPYVFVR.S "sp|P55769|NH2L1_HUMAN,tr|B1AHD1|B1AHD1_HUMAN,tr|A0A3B3ISH1|A0A3B3ISH1_HUMAN,tr|A0A3B3IUA2|A0A3B3IUA2_HUMAN,tr|A0A3B3IRU2|A0A3B3IRU2_HUMAN" 5 992.5444 1.7 3290 14617 2 992.543518 497.2795 NHP2-like protein 1 OS=Homo sapiens OX=9606 GN=SNU13 PE=1 SV=3 8.75 3099.9 - 612857 - - - -0.8393 - 1.105 0.222 - 123.2 1 2 0 -0.0008 8 0 0 0 7.42E+08 4.37E+08 - - - 0.9816 0.9987 221125_WJC_METTL3_EV_vs_WT_F01.14619.14619.2 0.00508 16-Aug K.ELGVGIALR.K sp|Q01469|FABP5_HUMAN 1 926.5549 45.56 3292 14619 2 926.553597 464.2847 Fatty acid-binding protein 5 OS=Homo sapiens OX=9606 GN=FABP5 PE=1 SV=3 6.1 3100 - 4.38E+06 - - - -1.4236 - 1.712 0.253 - 242.7 1 2 0 -0.0013 9 0 0 0 6.44E+08 1.41E+07 - - - 2.4647 0.9981 221125_WJC_METTL3_EV_vs_WT_F01.14623.14623.2 0.0197 16-Jun R.AFGYYGPLR.S "sp|P84103|SRSF3_HUMAN,tr|A0A087X2D0|A0A087X2D0_HUMAN" 2 1042.5236 1.2 3294 14623 2 1042.522116 522.2691 Serine\arginine-rich splicing factor 3 OS=Homo sapiens OX=9606 GN=SRSF3 PE=1 SV=1 8.63 3100.5 - 2.63E+06 - - - -1.4388 - 1.126 0.378 - 121.4 1 2 0 -0.0015 9 0 0 0 1.51E+09 1.26E+09 - - - 2.1758 0.9725 221125_WJC_METTL3_EV_vs_WT_F01.14625.14625.2 0.149 14-Aug K.GLVFLNGK.L sp|L0R8F8|MIDUO_HUMAN 1 846.4963 1.17 3296 14625 2 846.492491 424.2554 MIEF1 upstream open reading frame protein OS=Homo sapiens OX=9606 GN=MIEF1 PE=1 SV=1 8.75 3100.7 - 800128 - - - -4.5458 - 1.584 0.183 - 205.2 1 2 0 -0.0038 8 0 0 0 8.55E+07 7.31E+07 - - - 1.7786 0.9524 221125_WJC_METTL3_EV_vs_WT_F01.14631.14631.2 0.00337 14-Jul R.YPDGIISK[136.11].P sp|Q86U44|MTA70_HUMAN 1 899.4844 0.13 3299 14631 2 899.483054 450.7495 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 5.83 3101.3 - 1.43E+06 - - - -1.4775 - 1.509 0.36 - 130.9 1 1 0 -0.0013 8 0 0 0 1.96E+07 1.54E+08 - - - 2.9404 0.9991 221125_WJC_METTL3_EV_vs_WT_F01.14647.14647.2 0.0723 16-Sep R.LLLPTPTVK.Q "sp|Q8IX12|CCAR1_HUMAN,tr|A0A0C4DGG8|A0A0C4DGG8_HUMAN" 2 980.627 4.33 3308 14647 2 980.625444 491.3208 Cell division cycle and apoptosis regulator protein 1 OS=Homo sapiens OX=9606 GN=CCAR1 PE=1 SV=2 8.75 3103.3 - 4.78E+06 - - - -1.6061 - 1.58 0.356 - 268.5 1 2 0 -0.0016 9 0 0 0 5.84E+08 1.35E+08 - - - 2.9933 0.9985 221125_WJC_METTL3_EV_vs_WT_F01.14652.14652.2 0.0439 14-Jul K.NVPYVFVR[166.11].S "sp|P55769|NH2L1_HUMAN,tr|B1AHD1|B1AHD1_HUMAN,tr|A0A3B3ISH1|A0A3B3ISH1_HUMAN,tr|A0A3B3IUA2|A0A3B3IUA2_HUMAN,tr|A0A3B3IRU2|A0A3B3IRU2_HUMAN" 5 1002.5526 1.7 3311 14652 2 1002.551591 502.2836 NHP2-like protein 1 OS=Homo sapiens OX=9606 GN=SNU13 PE=1 SV=3 8.75 3104 - 1.35E+06 - - - -1.0274 - 1.282 0.325 - 226.3 1 2 0 -0.001 8 0 0 0 7.45E+08 4.38E+08 - - - 2.1904 0.953 221125_WJC_METTL3_EV_vs_WT_F01.14653.14653.2 0.023 12-Jul K.LYGFPYK.L "sp|Q9Y6G9|DC1L1_HUMAN,tr|E9PHI6|E9PHI6_HUMAN" 2 886.4589 0.31 3312 14653 2 886.455377 444.2367 Cytoplasmic dynein 1 light intermediate chain 1 OS=Homo sapiens OX=9606 GN=DYNC1LI1 PE=1 SV=3 8.5 3104.1 - 865923 - - - -3.963 - 1.131 0.219 - 153.6 1 2 0 -0.0035 7 0 0 0 1.96E+07 6.35E+07 - - - 1.0475 0.9936 221125_WJC_METTL3_EV_vs_WT_F01.14660.14660.2 0.0956 14-Jul K.LIINSLYK[136.11].N "sp|P14625|ENPL_HUMAN,tr|A0A7P0T917|A0A7P0T917_HUMAN,tr|A0A7P0Z405|A0A7P0Z405_HUMAN,tr|A0A7P0T823|A0A7P0T823_HUMAN,tr|A0A7P0TAE1|A0A7P0TAE1_HUMAN,tr|H0YIV0|H0YIV0_HUMAN,tr|A0A7P0T8R3|A0A7P0T8R3_HUMAN,tr|A0A7P0T885|A0A7P0T885_HUMAN,tr|A0A7P0TAY2|A0A7P0TAY2_HUMAN,tr|A0A087WT78|A0A087WT78_HUMAN,tr|F8W026|F8W026_HUMAN,tr|A0A7P0TBC2|A0A7P0TBC2_HUMAN,tr|A0A7P0TAT8|A0A7P0TAT8_HUMAN" 13 970.5943 0.85 3317 14660 2 970.592171 486.3044 Endoplasmin OS=Homo sapiens OX=9606 GN=HSP90B1 PE=1 SV=1 8.59 3104.9 - 1.00E+06 - - - -2.1605 - 1.389 0.209 - 120.5 1 2 0 -0.0021 8 0 0 0 1.35E+08 1.59E+08 - - - 1.575 0.9994 221125_WJC_METTL3_EV_vs_WT_F01.14661.14661.2 0.0854 18-Dec K.FGVVVVGVGR[166.11].A "sp|P53004|BIEA_HUMAN,tr|C9J1E1|C9J1E1_HUMAN" 2 997.5948 0.31 3318 14661 2 997.592646 499.8047 Biliverdin reductase A OS=Homo sapiens OX=9606 GN=BLVRA PE=1 SV=2 9.75 3105 - 1.51E+06 - - - -2.1802 - 2.25 0.328 - 432.3 1 2 0 -0.0022 10 0 0 0 2.44E+07 7.87E+07 - - - 3.7265 0.9997 221125_WJC_METTL3_EV_vs_WT_F01.14663.14663.2 2.09E-05 16-Sep K.MGYANEFLR.S "sp|Q8NDX5|PHC3_HUMAN,tr|E7EX82|E7EX82_HUMAN" 2 1099.5121 5.51 3320 14663 2 1099.510008 550.7633 Polyhomeotic-like protein 3 OS=Homo sapiens OX=9606 GN=PHC3 PE=1 SV=1 5.75 3105.2 - 635158 - - - -1.8708 - 1.695 0.51 - 305.1 1 2 0 -0.0021 9 0 0 0 3.41E+07 6.18E+06 - - - 4.3338 0.9998 221125_WJC_METTL3_EV_vs_WT_F01.14664.14664.2 0.000584 18-Oct R.FLSTTIVYPK.Y sp|Q8N5W9|RFLB_HUMAN 1 1167.654 0.96 3321 14664 2 1167.654517 584.8343 Refilin-B OS=Homo sapiens OX=9606 GN=RFLNB PE=1 SV=1 8.59 3105.4 - 561507 - - - 0.4753 - 1.721 0.465 - 243 1 2 0 0.0006 10 0 0 0 4.36E+07 4.54E+07 - - - 3.9907 0.9308 221125_WJC_METTL3_EV_vs_WT_F01.14669.14669.2 12.2 12-Aug R.LELLLQK[136.11].R "sp|Q8N3U4|STAG2_HUMAN,sp|Q53SZ7|PRR30_HUMAN,sp|Q8WVM7|STAG1_HUMAN,tr|Q68DW7|Q68DW7_HUMAN,tr|B1AMT4|B1AMT4_HUMAN" 5 863.5572 0.98 3323 14669 2 863.555108 432.7859 Cohesin subunit SA-2 OS=Homo sapiens OX=9606 GN=STAG2 PE=1 SV=3 6 3106 - 1.64E+06 - - - -2.3693 - 1.287 0.021 - 109.1 1 2 0 -0.002 7 0 0 0 5.93E+07 6.06E+07 - - - -0.0051 0.9976 221125_WJC_METTL3_EV_vs_WT_F01.14673.14673.2 0.0287 14-Aug K.GLVFLNGK[136.11].L sp|L0R8F8|MIDUO_HUMAN 1 854.5105 1.27 3325 14673 2 854.509074 428.2625 MIEF1 upstream open reading frame protein OS=Homo sapiens OX=9606 GN=MIEF1 PE=1 SV=1 8.75 3106.4 - 2.19E+06 - - - -1.7144 - 1.357 0.291 - 181.4 1 2 0 -0.0015 8 0 0 0 9.45E+07 7.42E+07 - - - 2.1106 0.9989 221125_WJC_METTL3_EV_vs_WT_F01.14681.14681.2 0.0292 16-Jul R.LLLPTPTVK[136.11].Q "sp|Q8IX12|CCAR1_HUMAN,tr|A0A0C4DGG8|A0A0C4DGG8_HUMAN" 2 988.6412 4.33 3328 14681 2 988.639551 495.3279 Cell division cycle and apoptosis regulator protein 1 OS=Homo sapiens OX=9606 GN=CCAR1 PE=1 SV=2 8.75 3107.4 - 2.74E+06 - - - -1.6862 - 1.411 0.374 - 167.5 1 2 0 -0.0017 9 0 0 0 6.04E+08 1.39E+08 - - - 2.7989 0.9996 221125_WJC_METTL3_EV_vs_WT_F01.14689.14689.2 9.33E-05 20-Nov R.VFSGLVSTGLK.V sp|P13639|EF2_HUMAN 1 1106.6336 0.48 3334 14689 2 1106.631121 554.3241 Elongation factor 2 OS=Homo sapiens OX=9606 GN=EEF2 PE=1 SV=4 8.72 3108.2 - 651623 - - - -2.204 - 1.808 0.524 - 324.9 1 2 0 -0.0024 11 0 0 0 4.48E+07 9.28E+07 - - - 4.5126 0.9998 221125_WJC_METTL3_EV_vs_WT_F01.14691.14691.2 6.83E-05 20-Oct R.VFSGLVSTGLK[136.11].V sp|P13639|EF2_HUMAN 1 1114.6478 0.48 3335 14691 2 1114.648863 558.3312 Elongation factor 2 OS=Homo sapiens OX=9606 GN=EEF2 PE=1 SV=4 8.72 3108.4 - 2.00E+06 - - - 0.9896 - 1.86 0.499 - 267.2 1 2 0 0.0011 11 0 0 0 4.48E+07 9.28E+07 - - - 4.4051 0.9978 221125_WJC_METTL3_EV_vs_WT_F01.14704.14704.2 0.0074 16-Aug K.LVELPYTVK[136.11].G sp|Q9NPF4|OSGEP_HUMAN 1 1068.631 0.41 3343 14704 2 1068.633229 535.3228 Probable tRNA N6-adenosine threonylcarbamoyltransferase OS=Homo sapiens OX=9606 GN=OSGEP PE=1 SV=1 6 3110 - 507431 - - - 2.0409 - 1.573 0.28 - 176.7 1 2 0 0.0022 9 0 0 0 1.49E+07 3.65E+07 - - - 2.4189 0.9996 221125_WJC_METTL3_EV_vs_WT_F01.14705.14705.2 0.00033 20-Sep R.LLC[160.03]GATLIAPR.W "sp|Q9UBX7|KLK11_HUMAN,tr|A0A0A0MR55|A0A0A0MR55_HUMAN,tr|M0QZV0|M0QZV0_HUMAN,tr|M0QZI8|M0QZI8_HUMAN" 4 1183.6747 999 3344 14705 2 1183.676242 592.8446 Kallikrein-11 OS=Homo sapiens OX=9606 GN=KLK11 PE=1 SV=2 8.25 3110.2 - 366129 - - - 1.2909 - 1.637 0.457 - 251.4 1 2 0 0.0015 11 0 0 0 5.16E+06 0.00E+00 - - - 3.7492 0.9996 221125_WJC_METTL3_EV_vs_WT_F01.14711.14711.2 2.98E-07 16-Nov K.YMAC[160.03]C[160.03]LLYR[166.11].G "sp|Q71U36|TBA1A_HUMAN,sp|A6NHL2|TBAL3_HUMAN,sp|P68366|TBA4A_HUMAN,sp|P68363|TBA1B_HUMAN,sp|Q9BQE3|TBA1C_HUMAN,tr|A0A1W2PQM2|A0A1W2PQM2_HUMAN,tr|F5H5D3|F5H5D3_HUMAN" 7 1258.5536 0.44 3348 14711 2 1258.549862 630.2841 Tubulin alpha-1A chain OS=Homo sapiens OX=9606 GN=TUBA1A PE=1 SV=1 8.05 3110.9 - 736522 - - - -2.9907 - 1.995 0.574 - 462.7 1 2 0 -0.0038 9 0 0 0 7.43E+07 1.69E+08 - - - 5.2775 0.9917 221125_WJC_METTL3_EV_vs_WT_F01.14717.14717.2 1.62 12-Jun K.LVFDGLR.K sp|P15924|DESP_HUMAN 1 818.465 2.99 3351 14717 2 818.464019 410.2398 Desmoplakin OS=Homo sapiens OX=9606 GN=DSP PE=1 SV=3 5.84 3111.6 - 2.89E+06 - - - -1.245 - 1.354 0.129 - 124.4 1 2 0 -0.001 7 0 0 0 5.58E+08 1.86E+08 - - - 0.9537 0.9998 221125_WJC_METTL3_EV_vs_WT_F01.14723.14723.2 9.77E-05 16-Sep K.YMAC[160.03]C[160.03]LLYR.G "sp|Q71U36|TBA1A_HUMAN,sp|A6NHL2|TBAL3_HUMAN,sp|P68366|TBA4A_HUMAN,sp|P68363|TBA1B_HUMAN,sp|Q9BQE3|TBA1C_HUMAN,tr|A0A1W2PQM2|A0A1W2PQM2_HUMAN,tr|F5H5D3|F5H5D3_HUMAN" 7 1248.5454 0.44 3355 14723 2 1248.545772 625.28 Tubulin alpha-1A chain OS=Homo sapiens OX=9606 GN=TUBA1A PE=1 SV=1 8.05 3112.4 - 868178 - - - 0.3332 - 1.573 0.524 - 296.1 1 2 0 0.0004 9 0 0 0 7.43E+07 1.69E+08 - - - 4.2216 0.9991 221125_WJC_METTL3_EV_vs_WT_F01.14736.14736.2 0.00264 16-Jul K.LVELPYTVK.G sp|Q9NPF4|OSGEP_HUMAN 1 1060.6168 0.4 3362 14736 2 1060.617973 531.3157 Probable tRNA N6-adenosine threonylcarbamoyltransferase OS=Homo sapiens OX=9606 GN=OSGEP PE=1 SV=1 6 3113.9 - 460537 - - - 1.0607 - 1.389 0.375 - 119 1 2 0 0.0011 9 0 0 0 1.49E+07 3.70E+07 - - - 2.761 0.9948 221125_WJC_METTL3_EV_vs_WT_F01.14738.14738.2 0.633 12-Jul K.FLAVLGR.G "sp|Q16512|PKN1_HUMAN,sp|Q86VR2|RETR3_HUMAN,tr|K7EQI9|K7EQI9_HUMAN,tr|K7EJ42|K7EJ42_HUMAN,tr|K7EL10|K7EL10_HUMAN" 5 774.4752 2 3364 14738 2 774.474409 388.2449 Serine\threonine-protein kinase N1 OS=Homo sapiens OX=9606 GN=PKN1 PE=1 SV=2 9.75 3114.1 - 1.58E+06 - - - -1.033 - 1.461 0.131 - 157.7 1 2 0 -0.0008 7 0 0 0 7.01E+07 3.51E+07 - - - 1.2096 0.9974 221125_WJC_METTL3_EV_vs_WT_F01.14746.14746.2 0.545 12-Jul R.IFIGTFK[136.11].A "sp|P63162|RSMN_HUMAN,sp|P14678|RSMB_HUMAN,tr|J3KRY3|J3KRY3_HUMAN,tr|J3QLE5|J3QLE5_HUMAN,tr|S4R3P3|S4R3P3_HUMAN" 5 832.4938 0.69 3370 14746 2 832.493613 417.2542 Small nuclear ribonucleoprotein-associated protein N OS=Homo sapiens OX=9606 GN=SNRPN PE=1 SV=1 8.75 3114.9 - 4.42E+06 - - - -0.2559 - 1.641 0.13 - 173.2 1 2 0 -0.0002 7 0 0 0 1.98E+09 2.89E+09 - - - 1.5705 0.9783 221125_WJC_METTL3_EV_vs_WT_F01.14747.14747.2 3.85 12-Jul R.IFIGTFK.A "sp|P63162|RSMN_HUMAN,sp|P14678|RSMB_HUMAN,tr|J3KRY3|J3KRY3_HUMAN,tr|J3QLE5|J3QLE5_HUMAN,tr|S4R3P3|S4R3P3_HUMAN" 5 824.4796 0.69 3371 14747 2 824.478758 413.2471 Small nuclear ribonucleoprotein-associated protein N OS=Homo sapiens OX=9606 GN=SNRPN PE=1 SV=1 8.75 3115 - 2.11E+06 - - - -1.0528 - 1.193 0.086 - 131.6 1 2 0 -0.0009 7 0 0 0 1.98E+09 2.89E+09 - - - 0.2351 0.9938 221125_WJC_METTL3_EV_vs_WT_F01.14754.14754.2 0.244 16-Sep R.LPEAAFLAR.T "sp|P35606|COPB2_HUMAN,tr|H0Y938|H0Y938_HUMAN,tr|A0A7I2V258|A0A7I2V258_HUMAN,tr|H0YAC7|H0YAC7_HUMAN" 4 986.5549 0.47 3376 14754 2 986.554414 494.2847 Coatomer subunit beta' OS=Homo sapiens OX=9606 GN=COPB2 PE=1 SV=2 6 3115.9 - 489693 - - - -0.5088 - 1.235 0.179 - 168.7 1 2 0 -0.0005 9 0 0 0 8.37E+07 1.77E+08 - - - 0.9736 0.9576 221125_WJC_METTL3_EV_vs_WT_F01.14763.14763.2 2.79 12-Jul K.LQQLWLK[136.11].A "sp|Q9NPC8|SIX2_HUMAN,sp|Q15475|SIX1_HUMAN" 2 935.5684 3.45 3381 14763 2 935.568878 468.7915 Homeobox protein SIX2 OS=Homo sapiens OX=9606 GN=SIX2 PE=1 SV=1 8.75 3117 - 1.16E+06 - - - 0.5237 - 1.158 0.03 - 152.7 1 2 0 0.0005 7 0 0 0 1.54E+08 4.46E+07 - - - -0.2728 0.9508 221125_WJC_METTL3_EV_vs_WT_F01.14771.14771.2 3.77 14-May R.LFIGGIPK.M "sp|A0AV96|RBM47_HUMAN,tr|D6RBS9|D6RBS9_HUMAN,tr|B7Z8Z7|B7Z8Z7_HUMAN,tr|D6REZ6|D6REZ6_HUMAN,tr|D6R9D6|D6R9D6_HUMAN" 5 843.5218 1.58 3386 14771 2 843.52108 422.7682 RNA-binding protein 47 OS=Homo sapiens OX=9606 GN=RBM47 PE=1 SV=2 8.75 3117.8 - 536718 - - - -0.8832 - 1.096 0.097 - 74.4 7 2 0 -0.0007 8 0 0 0 9.69E+07 6.12E+07 - - - -0.3438 0.9755 221125_WJC_METTL3_EV_vs_WT_F01.14780.14780.2 0.0975 16-Jul R.YLYLSTMER[166.11].S "sp|Q10570|CPSF1_HUMAN,tr|A0A087X101|A0A087X101_HUMAN" 2 1184.5775 34.39 3391 14780 2 1184.572165 593.296 Cleavage and polyadenylation specificity factor subunit 1 OS=Homo sapiens OX=9606 GN=CPSF1 PE=1 SV=2 6 3118.8 - 326878 - - - -4.5172 - 1.263 0.29 - 168.6 1 2 0 -0.0053 9 0 0 0 7.46E+08 2.17E+07 - - - 1.8568 0.9971 221125_WJC_METTL3_EV_vs_WT_F01.14792.14792.2 0.169 12-Jul K.SEFVILR.D "sp|P54577|SYYC_HUMAN,tr|A0A6Q8PFX2|A0A6Q8PFX2_HUMAN" 2 862.4913 0.55 3395 14792 2 862.491558 432.2529 "Tyrosine--tRNA ligase, cytoplasmic OS=Homo sapiens OX=9606 GN=YARS1 PE=1 SV=4" 5.72 3120.4 - 489356 - - - 0.3536 - 1.433 0.185 - 190.8 1 2 0 0.0003 7 0 0 0 5.23E+07 9.57E+07 - - - 1.5473 0.9607 221125_WJC_METTL3_EV_vs_WT_F01.14794.14794.2 1.06 12-Jun K.SEFVILR[166.11].D "sp|P54577|SYYC_HUMAN,tr|A0A6Q8PFX2|A0A6Q8PFX2_HUMAN" 2 872.4995 0.55 3396 14794 2 872.496864 437.257 "Tyrosine--tRNA ligase, cytoplasmic OS=Homo sapiens OX=9606 GN=YARS1 PE=1 SV=4" 5.72 3120.6 - 1.17E+06 - - - -3.0476 - 1.231 0.137 - 122 1 2 0 -0.0027 7 0 0 0 5.23E+07 9.60E+07 - - - 0.7106 0.9996 221125_WJC_METTL3_EV_vs_WT_F01.14797.14797.2 0.000311 16-Sep R.LPEAAFLAR[166.11].T "sp|P35606|COPB2_HUMAN,tr|H0Y938|H0Y938_HUMAN,tr|A0A7I2V258|A0A7I2V258_HUMAN,tr|H0YAC7|H0YAC7_HUMAN" 4 996.5632 0.49 3397 14797 2 996.561944 499.2889 Coatomer subunit beta' OS=Homo sapiens OX=9606 GN=COPB2 PE=1 SV=2 6 3121 - 3.92E+06 - - - -1.2463 - 1.792 0.402 - 293 1 2 0 -0.0012 9 0 0 0 8.72E+07 1.80E+08 - - - 3.6974 0.9393 221125_WJC_METTL3_EV_vs_WT_F01.14819.14819.2 4.19 14-Jun R.LFIGGIPK[136.11].M "sp|A0AV96|RBM47_HUMAN,tr|D6RBS9|D6RBS9_HUMAN,tr|B7Z8Z7|B7Z8Z7_HUMAN,tr|D6REZ6|D6REZ6_HUMAN,tr|D6R9D6|D6R9D6_HUMAN" 5 851.536 1.47 3403 14819 2 851.538022 426.7753 RNA-binding protein 47 OS=Homo sapiens OX=9606 GN=RBM47 PE=1 SV=2 8.75 3124.1 - 1.06E+06 - - - 2.3452 - 1.187 0.103 - 105.5 3 2 0 0.002 8 0 0 0 8.97E+07 6.12E+07 - - - 0.105 0.9742 221125_WJC_METTL3_EV_vs_WT_F01.14821.14821.2 0.968 12-Aug R.IYLYLTK.V "sp|P41250|GARS_HUMAN,tr|H7C443|H7C443_HUMAN,tr|A0A6Q8PGI6|A0A6Q8PGI6_HUMAN,tr|A0A6Q8PGA8|A0A6Q8PGA8_HUMAN,tr|A0A6Q8PGW4|A0A6Q8PGW4_HUMAN,tr|A0A6Q8PGZ8|A0A6Q8PGZ8_HUMAN,tr|A0A6Q8PHH9|A0A6Q8PHH9_HUMAN,tr|A0A6Q8PHI7|A0A6Q8PHI7_HUMAN,tr|A0A6Q8PFZ6|A0A6Q8PFZ6_HUMAN" 9 912.5321 1.26 3404 14821 2 912.530059 457.2733 Glycine--tRNA ligase OS=Homo sapiens OX=9606 GN=GARS1 PE=1 SV=3 8.5 3124.3 - 6.21E+06 - - - -2.1873 - 1.436 0.053 - 236.1 1 2 0 -0.002 7 0 0 0 2.10E+08 1.66E+08 - - - 0.5784 0.9996 221125_WJC_METTL3_EV_vs_WT_F01.14829.14829.2 0.000101 15/20 R.IALTDNALIAR[166.11].S "sp|P18124|RL7_HUMAN,tr|A8MUD9|A8MUD9_HUMAN" 2 1179.6851 0.88 3407 14829 2 1179.682234 590.8498 60S ribosomal protein L7 OS=Homo sapiens OX=9606 GN=RPL7 PE=1 SV=1 5.84 3125.4 - 1.08E+06 - - - -2.4227 - 2.699 0.386 - 818.8 1 2 0 -0.0029 11 0 0 0 5.73E+07 6.54E+07 - - - 4.5771 0.9746 221125_WJC_METTL3_EV_vs_WT_F01.14831.14831.2 0.00838 16-Aug R.PAVLSGYFK[136.11].Q "sp|Q9Y520|PRC2C_HUMAN,tr|E7EPN9|E7EPN9_HUMAN" 2 988.5473 0.92 3408 14831 2 988.548609 495.2809 Protein PRRC2C OS=Homo sapiens OX=9606 GN=PRRC2C PE=1 SV=4 9.01 3125.6 - 2.72E+06 - - - 1.306 - 1.978 0.357 - 204.7 1 1 0 0.0013 9 0 0 0 1.48E+08 1.61E+08 - - - 3.6507 0.9816 221125_WJC_METTL3_EV_vs_WT_F01.14835.14835.2 0.000816 16-Oct R.PAVLSGYFK.Q "sp|Q9Y520|PRC2C_HUMAN,tr|E7EPN9|E7EPN9_HUMAN" 2 980.5331 0.92 3409 14835 2 980.531417 491.2738 Protein PRRC2C OS=Homo sapiens OX=9606 GN=PRRC2C PE=1 SV=4 9.01 3126.2 - 3.34E+06 - - - -1.7348 - 1.991 0.44 - 378.4 1 1 0 -0.0017 9 0 0 0 1.48E+08 1.60E+08 - - - 4.2826 0.9678 221125_WJC_METTL3_EV_vs_WT_F01.14836.14836.2 0.0253 12-Aug K.TSILVFK.D sp|Q9BRS2|RIOK1_HUMAN 1 806.4902 1.11 3410 14836 2 806.485725 404.2524 Serine\threonine-protein kinase RIO1 OS=Homo sapiens OX=9606 GN=RIOK1 PE=1 SV=2 8.41 3126.3 - 1.02E+06 - - - -5.5376 - 1.519 0.252 - 198 1 2 0 -0.0045 7 0 0 0 3.95E+07 3.57E+07 - - - 2.2255 0.9994 221125_WJC_METTL3_EV_vs_WT_F01.14837.14837.2 0.00753 14-Aug R.GFTLVGMK[136.11].M "sp|O00746|NDKM_HUMAN,tr|Q4TT34|Q4TT34_HUMAN,tr|A0A087WVT9|A0A087WVT9_HUMAN,tr|H0Y6J0|H0Y6J0_HUMAN,tr|F2Z2X0|F2Z2X0_HUMAN" 5 859.4717 1.66 3411 14837 2 859.471205 430.7431 "Nucleoside diphosphate kinase, mitochondrial OS=Homo sapiens OX=9606 GN=NME4 PE=1 SV=1" 8.75 3126.4 - 2.09E+06 - - - -0.5876 - 1.754 0.301 - 258.9 1 2 0 -0.0005 8 0 0 0 7.42E+08 4.47E+08 - - - 2.9587 0.9983 221125_WJC_METTL3_EV_vs_WT_F01.14838.14838.2 0.000112 14-Aug R.FADFTVYR.N "sp|Q9NY61|AATF_HUMAN,tr|A0A7P0T868|A0A7P0T868_HUMAN,tr|A0A7P0TAR0|A0A7P0TAR0_HUMAN,tr|A0A7P0TBI0|A0A7P0TBI0_HUMAN,tr|A0A7P0Z4P2|A0A7P0Z4P2_HUMAN,tr|A0A7P0Z4N2|A0A7P0Z4N2_HUMAN,tr|A0A087WTH8|A0A087WTH8_HUMAN,tr|A0A7P0Z434|A0A7P0Z434_HUMAN" 8 1017.492 1.23 3412 14838 2 1017.488998 509.7533 Protein AATF OS=Homo sapiens OX=9606 GN=AATF PE=1 SV=1 5.84 3126.5 - 978444 - - - -2.9327 - 1.689 0.361 - 164.1 1 2 0 -0.003 8 0 0 0 3.97E+07 3.21E+07 - - - 3.2872 0.9403 221125_WJC_METTL3_EV_vs_WT_F01.14843.14843.2 0.174 12-Aug R.WGGLDLR.R sp|Q9H7N4|SFR19_HUMAN 1 815.429 999 3415 14843 2 815.425003 408.7218 "Splicing factor, arginine\serine-rich 19 OS=Homo sapiens OX=9606 GN=SCAF1 PE=1 SV=3" 5.84 3127.1 - 1.77E+06 - - - -4.8858 - 1.238 0.221 - 250.6 1 2 0 -0.004 7 0 0 0 5.13E+07 0.00E+00 - - - 1.3485 0.9818 221125_WJC_METTL3_EV_vs_WT_F01.14845.14845.2 1.07 12-Aug K.LC[160.03]TFILK[136.11].N "sp|P55010|IF5_HUMAN,tr|H0YLZ1|H0YLZ1_HUMAN,tr|H0YN40|H0YN40_HUMAN" 3 901.5187 0.71 3417 14845 2 901.518185 451.7666 Eukaryotic translation initiation factor 5 OS=Homo sapiens OX=9606 GN=EIF5 PE=1 SV=2 8.22 3127.3 - 945346 - - - -0.528 - 1.263 0.062 - 172.6 1 2 0 -0.0005 7 0 0 0 1.98E+07 2.80E+07 - - - 0.2386 0.9199 221125_WJC_METTL3_EV_vs_WT_F01.14848.14848.2 7.2 16-Jun R.VGVAAVGNR.L "sp|Q6TDP4|KLH17_HUMAN,tr|Q0VGE6|Q0VGE6_HUMAN" 2 841.477 2.38 3418 14848 2 841.477876 421.7458 Kelch-like protein 17 OS=Homo sapiens OX=9606 GN=KLHL17 PE=1 SV=1 9.72 3127.7 - 2.26E+06 - - - 1.041 - 1.195 0.002 - 85.1 2 2 0 0.0009 9 0 0 0 7.14E+07 3.00E+07 - - - -0.5636 0.9793 221125_WJC_METTL3_EV_vs_WT_F01.14849.14849.2 0.0668 12-Jun R.ALTALFK[136.11].E "sp|Q9UBB4|ATX10_HUMAN,tr|A0A1W2PQD2|A0A1W2PQD2_HUMAN" 2 770.4782 8.04 3419 14849 2 770.47747 386.2464 Ataxin-10 OS=Homo sapiens OX=9606 GN=ATXN10 PE=1 SV=1 8.8 3127.8 - 2.13E+06 - - - -0.9163 - 1.317 0.061 - 127.1 2 2 0 -0.0007 7 0 0 0 3.02E+08 3.75E+07 - - - 0.2293 0.9995 221125_WJC_METTL3_EV_vs_WT_F01.14851.14851.2 0.000189 28-Dec R.NFILDQTNVSAAAQR[166.11].R "sp|Q00839|HNRPU_HUMAN,tr|A0A1W2PQL0|A0A1W2PQL0_HUMAN,tr|A0A1W2PPL4|A0A1W2PPL4_HUMAN,tr|A0A1W2PQ74|A0A1W2PQ74_HUMAN,tr|Q5RI18|Q5RI18_HUMAN,tr|A0A1W2PP35|A0A1W2PP35_HUMAN,tr|A0A1W2PPS1|A0A1W2PPS1_HUMAN,tr|A0A1W2PRZ7|A0A1W2PRZ7_HUMAN,tr|A0A1W2PPH7|A0A1W2PPH7_HUMAN,tr|A0A1W2PQD4|A0A1W2PQD4_HUMAN,tr|A0A1W2PP34|A0A1W2PP34_HUMAN,tr|A0A1X7SBS1|A0A1X7SBS1_HUMAN" 12 1656.8459 0.6 3421 14851 2 1656.843075 829.4302 Heterogeneous nuclear ribonucleoprotein U OS=Homo sapiens OX=9606 GN=HNRNPU PE=1 SV=6 5.84 3128.1 - 649570 - - - -1.7069 - 1.965 0.398 - 173 1 2 0 -0.0028 15 0 0 0 7.16E+06 1.19E+07 - - - 3.6405 0.9983 221125_WJC_METTL3_EV_vs_WT_F01.14862.14862.2 1.6 18-Aug K.IVLLSANSIR.A "sp|O95071|UBR5_HUMAN,tr|E7EMW7|E7EMW7_HUMAN" 2 1084.6604 15.13 3427 14862 2 1084.658559 543.3375 E3 ubiquitin-protein ligase UBR5 OS=Homo sapiens OX=9606 GN=UBR5 PE=1 SV=2 9.75 3129.5 - 606162 - - - -1.7379 - 1.769 0.242 - 186.9 1 2 0 -0.0019 10 0 0 0 1.79E+07 1.18E+06 - - - 2.42 0.9944 221125_WJC_METTL3_EV_vs_WT_F01.14865.14865.2 0.119 14-Aug K.LGFESIYK.L "sp|P49643|PRI2_HUMAN,tr|A0A5F9ZHU7|A0A5F9ZHU7_HUMAN" 2 955.5015 8.44 3429 14865 2 955.502214 478.758 DNA primase large subunit OS=Homo sapiens OX=9606 GN=PRIM2 PE=1 SV=2 6 3129.8 - 667263 - - - 0.764 - 1.534 0.11 - 120.9 1 2 0 0.0007 8 0 0 0 1.91E+08 2.26E+07 - - - 1.1437 0.9998 221125_WJC_METTL3_EV_vs_WT_F01.14866.14866.2 7.96E-05 20-Nov K.IGLFGGAGVGK[136.11].T "sp|P06576|ATPB_HUMAN,tr|F8W079|F8W079_HUMAN,tr|F8W0P7|F8W0P7_HUMAN,tr|H0YH81|H0YH81_HUMAN" 4 982.5691 1.95 3430 14866 2 982.569274 492.2918 "ATP synthase subunit beta, mitochondrial OS=Homo sapiens OX=9606 GN=ATP5F1B PE=1 SV=3" 8.75 3129.9 - 3.47E+06 - - - 0.1608 - 2.238 0.374 - 248.4 1 2 0 0.0002 11 0 0 0 5.69E+08 2.91E+08 - - - 3.9826 0.9943 221125_WJC_METTL3_EV_vs_WT_F01.14870.14870.2 0.977 16-Sep K.ELGVGIALR.K sp|Q01469|FABP5_HUMAN 1 926.5549 9.36 3433 14870 2 926.553419 464.2847 Fatty acid-binding protein 5 OS=Homo sapiens OX=9606 GN=FABP5 PE=1 SV=3 6.1 3130.4 - 1.71E+06 - - - -1.6157 - 1.503 0.157 - 291.4 1 2 0 -0.0015 9 0 0 0 1.58E+08 1.69E+07 - - - 1.3789 0.9877 221125_WJC_METTL3_EV_vs_WT_F01.14872.14872.2 0.151 12-Jun K.GDLLEVK[136.11].D sp|Q14CX7|NAA25_HUMAN 1 780.4473 1.09 3435 14872 2 780.44577 391.2309 "N-alpha-acetyltransferase 25, NatB auxiliary subunit OS=Homo sapiens OX=9606 GN=NAA25 PE=1 SV=1" 4.37 3130.7 - 786023 - - - -1.922 - 1.342 0.135 - 149.2 1 2 0 -0.0015 7 0 0 0 1.00E+07 9.19E+06 - - - 0.9697 0.9976 221125_WJC_METTL3_EV_vs_WT_F01.14875.14875.2 0.0218 14-Jun K.NVPYVFVR.S "sp|P55769|NH2L1_HUMAN,tr|B1AHD1|B1AHD1_HUMAN,tr|A0A3B3ISH1|A0A3B3ISH1_HUMAN,tr|A0A3B3IUA2|A0A3B3IUA2_HUMAN,tr|A0A3B3IRU2|A0A3B3IRU2_HUMAN" 5 992.5444 1.7 3436 14875 2 992.544921 497.2795 NHP2-like protein 1 OS=Homo sapiens OX=9606 GN=SNU13 PE=1 SV=3 8.75 3131.1 - 3.29E+06 - - - 0.5743 - 1.117 0.318 - 123 1 2 0 0.0006 8 0 0 0 7.45E+08 4.39E+08 - - - 1.7233 0.9837 221125_WJC_METTL3_EV_vs_WT_F01.14881.14881.2 0.219 14-Jul R.LLFGPTVR[166.11].L "sp|Q9Y399|RT02_HUMAN,tr|Q5T8A0|Q5T8A0_HUMAN" 2 911.5468 0.33 3439 14881 2 911.544507 456.7807 "28S ribosomal protein S2, mitochondrial OS=Homo sapiens OX=9606 GN=MRPS2 PE=1 SV=1" 9.75 3131.8 - 1.33E+06 - - - -2.5243 - 1.202 0.2 - 136.3 1 2 0 -0.0023 8 0 0 0 2.50E+07 7.63E+07 - - - 1.0724 0.9996 221125_WJC_METTL3_EV_vs_WT_F01.14885.14885.2 0.00108 18-Sep R.LITLEEEMTK.Y "sp|P07237|PDIA1_HUMAN,tr|A0A7P0TA97|A0A7P0TA97_HUMAN,tr|A0A7P0T8C0|A0A7P0T8C0_HUMAN,tr|H7BZ94|H7BZ94_HUMAN,tr|A0A7P0TA71|A0A7P0TA71_HUMAN,tr|I3L4M2|I3L4M2_HUMAN,tr|A0A7P0T9D6|A0A7P0T9D6_HUMAN,tr|A0A7P0T9K9|A0A7P0T9K9_HUMAN,tr|H0Y3Z3|H0Y3Z3_HUMAN,tr|A0A7P0TA35|A0A7P0TA35_HUMAN,tr|I3L514|I3L514_HUMAN,tr|A0A7P0TB26|A0A7P0TB26_HUMAN,tr|A0A7P0T9U6|A0A7P0T9U6_HUMAN,tr|I3L0S0|I3L0S0_HUMAN,tr|I3L3P5|I3L3P5_HUMAN,tr|A0A7P0T8J3|A0A7P0T8J3_HUMAN,tr|A0A7P0T8X1|A0A7P0T8X1_HUMAN" 17 1205.6213 1.33 3443 14885 2 1205.618268 603.8179 Protein disulfide-isomerase OS=Homo sapiens OX=9606 GN=P4HB PE=1 SV=3 4.25 3132.1 - 920998 - - - -2.5489 - 2.017 0.497 - 187.3 1 2 0 -0.0031 10 0 0 0 7.80E+07 5.88E+07 - - - 4.6693 0.9718 221125_WJC_METTL3_EV_vs_WT_F01.14887.14887.2 0.0239 22-Jul K.VLPPPAGYVPIR.T sp|O75533|SF3B1_HUMAN 1 1277.7496 1.29 3445 14887 2 1277.744245 639.8821 Splicing factor 3B subunit 1 OS=Homo sapiens OX=9606 GN=SF3B1 PE=1 SV=3 8.72 3132.4 - 248287 - - - -4.1855 - 1.468 0.204 - 102.2 1 2 0 -0.0053 12 0 0 0 4.65E+07 3.60E+07 - - - 1.5562 0.9994 221125_WJC_METTL3_EV_vs_WT_F01.14891.14891.2 4.27E-05 16-Nov K.LGEWVGLC[160.03]K.L sp|P25398|RS12_HUMAN 1 1060.5376 1.76 3447 14891 2 1060.534306 531.2761 40S ribosomal protein S12 OS=Homo sapiens OX=9606 GN=RPS12 PE=1 SV=3 5.99 3132.9 - 2.06E+06 - - - -3.0607 - 2.187 0.475 - 455.2 1 2 0 -0.0032 9 0 0 0 3.93E+08 2.23E+08 - - - 4.8122 0.9997 221125_WJC_METTL3_EV_vs_WT_F01.14892.14892.2 0.0484 14-Aug R.GFTLVGMK.M "sp|O00746|NDKM_HUMAN,tr|Q4TT34|Q4TT34_HUMAN,tr|A0A087WVT9|A0A087WVT9_HUMAN,tr|H0Y6J0|H0Y6J0_HUMAN,tr|F2Z2X0|F2Z2X0_HUMAN" 5 851.4575 1.66 3448 14892 2 851.456772 426.736 "Nucleoside diphosphate kinase, mitochondrial OS=Homo sapiens OX=9606 GN=NME4 PE=1 SV=1" 8.75 3132.9 - 4.50E+07 - - - -0.8667 - 1.833 0.386 - 266.2 1 2 0 -0.0007 8 0 0 0 7.42E+08 4.47E+08 - - - 3.7193 0.9998 221125_WJC_METTL3_EV_vs_WT_F01.14894.14894.2 0.0022 18-Sep R.LITLEEEMTK[136.11].Y "sp|P07237|PDIA1_HUMAN,tr|A0A7P0TA97|A0A7P0TA97_HUMAN,tr|A0A7P0T8C0|A0A7P0T8C0_HUMAN,tr|H7BZ94|H7BZ94_HUMAN,tr|A0A7P0TA71|A0A7P0TA71_HUMAN,tr|I3L4M2|I3L4M2_HUMAN,tr|A0A7P0T9D6|A0A7P0T9D6_HUMAN,tr|A0A7P0T9K9|A0A7P0T9K9_HUMAN,tr|H0Y3Z3|H0Y3Z3_HUMAN,tr|A0A7P0TA35|A0A7P0TA35_HUMAN,tr|I3L514|I3L514_HUMAN,tr|A0A7P0TB26|A0A7P0TB26_HUMAN,tr|A0A7P0T9U6|A0A7P0T9U6_HUMAN,tr|I3L0S0|I3L0S0_HUMAN,tr|I3L3P5|I3L3P5_HUMAN,tr|A0A7P0T8J3|A0A7P0T8J3_HUMAN,tr|A0A7P0T8X1|A0A7P0T8X1_HUMAN" 17 1213.6355 1.32 3450 14894 2 1213.63506 607.825 Protein disulfide-isomerase OS=Homo sapiens OX=9606 GN=P4HB PE=1 SV=3 4.25 3133.1 - 1.51E+06 - - - -0.3963 - 1.963 0.451 - 215.7 1 2 0 -0.0005 10 0 0 0 7.76E+07 5.88E+07 - - - 4.2546 0.9801 221125_WJC_METTL3_EV_vs_WT_F01.14895.14895.2 1.3 14-Jun R.LLFGPTVR.L "sp|Q9Y399|RT02_HUMAN,tr|Q5T8A0|Q5T8A0_HUMAN" 2 901.5385 0.36 3451 14895 2 901.537179 451.7765 "28S ribosomal protein S2, mitochondrial OS=Homo sapiens OX=9606 GN=MRPS2 PE=1 SV=1" 9.75 3133.1 - 1.10E+06 - - - -1.5074 - 1.225 0.108 - 94.1 1 2 0 -0.0014 8 0 0 0 2.48E+07 6.94E+07 - - - 0.4503 0.9918 221125_WJC_METTL3_EV_vs_WT_F01.14899.14899.2 0.192 22-Jun K.VLPPPAGYVPIR[166.11].T sp|O75533|SF3B1_HUMAN 1 1287.7579 1.29 3455 14899 2 1287.756918 644.8862 Splicing factor 3B subunit 1 OS=Homo sapiens OX=9606 GN=SF3B1 PE=1 SV=3 8.72 3133.7 - 220500 - - - -0.7338 - 1.29 0.149 - 80.5 1 2 0 -0.0009 12 0 0 0 4.65E+07 3.60E+07 - - - 0.8112 0.9999 221125_WJC_METTL3_EV_vs_WT_F01.14902.14902.2 0.0111 15/20 K.IGLFGGAGVGK.T "sp|P06576|ATPB_HUMAN,tr|F8W079|F8W079_HUMAN,tr|F8W0P7|F8W0P7_HUMAN,tr|H0YH81|H0YH81_HUMAN" 4 974.5549 1.75 3456 14902 2 974.554 488.2847 "ATP synthase subunit beta, mitochondrial OS=Homo sapiens OX=9606 GN=ATP5F1B PE=1 SV=3" 8.75 3134.1 - 2.46E+07 - - - -0.9399 - 2.512 0.46 - 587.9 1 2 0 -0.0009 11 0 0 0 5.08E+08 2.90E+08 - - - 4.93 0.9994 221125_WJC_METTL3_EV_vs_WT_F01.14904.14904.2 0.264 14-Aug R.IGQFVFAR.D sp|Q9NRN7|ADPPT_HUMAN 1 936.5181 0.49 3458 14904 2 936.51783 469.2663 L-aminoadipate-semialdehyde dehydrogenase-phosphopantetheinyl transferase OS=Homo sapiens OX=9606 GN=AASDHPPT PE=1 SV=2 9.75 3134.3 - 1.05E+06 - - - -0.3278 - 1.826 0.272 - 206.3 1 2 0 -0.0003 8 0 0 0 2.48E+07 5.04E+07 - - - 2.8659 0.9993 221125_WJC_METTL3_EV_vs_WT_F01.14905.14905.2 0.00372 18-Oct K.VLFTGVVDAR.G sp|Q14676|MDC1_HUMAN 1 1075.6026 0.99 3459 14905 2 1075.599345 538.8086 Mediator of DNA damage checkpoint protein 1 OS=Homo sapiens OX=9606 GN=MDC1 PE=1 SV=3 5.81 3134.4 - 849211 - - - -3.0216 - 2.265 0.428 - 418.2 1 2 0 -0.0032 10 0 0 0 2.68E+07 2.70E+07 - - - 4.4833 0.9781 221125_WJC_METTL3_EV_vs_WT_F01.14914.14914.2 3.53 14-Jul K.NVPYVFVR[166.11].S "sp|P55769|NH2L1_HUMAN,tr|B1AHD1|B1AHD1_HUMAN,tr|A0A3B3ISH1|A0A3B3ISH1_HUMAN,tr|A0A3B3IUA2|A0A3B3IUA2_HUMAN,tr|A0A3B3IRU2|A0A3B3IRU2_HUMAN" 5 1002.5526 1.7 3467 14914 2 1002.551118 502.2836 NHP2-like protein 1 OS=Homo sapiens OX=9606 GN=SNU13 PE=1 SV=3 8.75 3135.6 - 1.51E+06 - - - -1.4992 - 1.189 0.111 - 201.9 1 2 0 -0.0015 8 0 0 0 7.36E+08 4.33E+08 - - - 0.3825 0.9996 221125_WJC_METTL3_EV_vs_WT_F01.14915.14915.2 0.00219 14-Sep K.LFQVLAPR[166.11].Y "sp|Q9NRX2|RM17_HUMAN,tr|E9PKV2|E9PKV2_HUMAN" 2 952.5734 1.63 3468 14915 2 952.571915 477.294 "39S ribosomal protein L17, mitochondrial OS=Homo sapiens OX=9606 GN=MRPL17 PE=1 SV=1" 9.75 3135.6 - 2.41E+06 - - - -1.5138 - 1.957 0.379 - 335.1 1 2 0 -0.0014 8 0 0 0 7.92E+07 4.86E+07 - - - 3.8648 0.9962 221125_WJC_METTL3_EV_vs_WT_F01.14916.14916.2 0.911 12-Jul R.FLVTVIK.D "sp|O14980|XPO1_HUMAN,tr|A0A7I2V488|A0A7I2V488_HUMAN,tr|A0A7I2V461|A0A7I2V461_HUMAN,tr|A0A7I2V2H0|A0A7I2V2H0_HUMAN,tr|A0A7I2V3N0|A0A7I2V3N0_HUMAN,tr|A0A7I2V4A3|A0A7I2V4A3_HUMAN,tr|A0A7I2V3W6|A0A7I2V3W6_HUMAN,tr|A0A7I2YQV4|A0A7I2YQV4_HUMAN,tr|A0A7I2YQX3|A0A7I2YQX3_HUMAN,tr|A0A7I2V2Y6|A0A7I2V2Y6_HUMAN,tr|A0A7I2V6B9|A0A7I2V6B9_HUMAN,tr|A0A7I2V3P3|A0A7I2V3P3_HUMAN,tr|A0A7I2V2S3|A0A7I2V2S3_HUMAN" 13 818.5266 0.52 3469 14916 2 818.525514 410.2706 Exportin-1 OS=Homo sapiens OX=9606 GN=XPO1 PE=1 SV=1 8.75 3135.7 - 933847 - - - -1.2975 - 1.509 0.162 - 142 1 2 0 -0.0011 7 0 0 0 1.63E+07 3.15E+07 - - - 1.5409 0.8436 221125_WJC_METTL3_EV_vs_WT_F01.14937.14937.2 2.06 12-May R.LDPVLFK[136.11].D "sp|Q16394|EXT1_HUMAN,sp|Q92935|EXTL1_HUMAN" 2 838.5044 32.2 3486 14937 2 838.505837 420.2595 Exostosin-1 OS=Homo sapiens OX=9606 GN=EXT1 PE=1 SV=2 5.84 3138.3 - 448020 - - - 1.7245 - 1.197 0.014 - 47.7 14 2 0 0.0014 7 0 0 0 2.46E+08 7.65E+06 - - - -0.7983 0.9989 221125_WJC_METTL3_EV_vs_WT_F01.14939.14939.2 0.15 18-Aug K.SYLYPSTLVR.T "sp|P52732|KIF11_HUMAN,tr|A0A7I2V3A9|A0A7I2V3A9_HUMAN" 2 1197.6394 4.29 3488 14939 2 1197.641566 599.827 Kinesin-like protein KIF11 OS=Homo sapiens OX=9606 GN=KIF11 PE=1 SV=2 8.31 3138.6 - 378924 - - - 1.8303 - 1.837 0.305 - 260.8 1 2 0 0.0022 10 0 0 0 1.23E+09 2.87E+08 - - - 2.9905 0.9012 221125_WJC_METTL3_EV_vs_WT_F01.14952.14952.2 0.489 14-Jul A.LSGISLLK.L tr|H3BNU2|H3BNU2_HUMAN 1 829.5273 0.8 3497 14952 2 829.526745 415.7709 N-acetylgalactosamine-6-sulfatase OS=Homo sapiens OX=9606 GN=GALNS PE=4 SV=1 8.75 3140.2 - 602234 - - - -0.6739 - 1.475 0.231 - 136.5 1 1 0 -0.0006 8 0 0 0 5.23E+07 6.54E+07 - - - 1.9192 0.9994 221125_WJC_METTL3_EV_vs_WT_F01.14958.14958.2 0.00774 12-Jul M.GVPAFFR[166.11].W sp|Q9H0D6|XRN2_HUMAN 1 802.4365 0.9 3501 14958 2 802.436841 402.2255 5'-3' exoribonuclease 2 OS=Homo sapiens OX=9606 GN=XRN2 PE=1 SV=1 9.75 3140.9 - 862952 - - - 0.3888 - 1.387 0.374 - 200.2 1 2 0 0.0003 7 0 0 0 1.63E+08 1.81E+08 - - - 2.8398 0.9944 221125_WJC_METTL3_EV_vs_WT_F01.14959.14959.2 0.26 12-Jun M.GVPAFFR.W sp|Q9H0D6|XRN2_HUMAN 1 792.4283 0.9 3502 14959 2 792.42852 397.2214 5'-3' exoribonuclease 2 OS=Homo sapiens OX=9606 GN=XRN2 PE=1 SV=1 9.75 3141.1 - 558191 - - - 0.3294 - 1.187 0.198 - 149.4 1 2 0 0.0003 7 0 0 0 1.62E+08 1.80E+08 - - - 1.0465 0.9999 221125_WJC_METTL3_EV_vs_WT_F01.14963.14963.2 0.000369 16-Oct K.LGEWVGLC[160.03]K[136.11].L sp|P25398|RS12_HUMAN 1 1068.5518 1.97 3505 14963 2 1068.551607 535.2832 40S ribosomal protein S12 OS=Homo sapiens OX=9606 GN=RPS12 PE=1 SV=3 5.99 3141.5 - 8.07E+06 - - - -0.1357 - 2.214 0.466 - 376 1 2 0 -0.0001 9 0 0 0 4.41E+08 2.24E+08 - - - 4.7822 0.999 221125_WJC_METTL3_EV_vs_WT_F01.14965.14965.2 0.0493 18-Aug K.SYLYPSTLVR[166.11].T "sp|P52732|KIF11_HUMAN,tr|A0A7I2V3A9|A0A7I2V3A9_HUMAN" 2 1207.6476 4.29 3506 14965 2 1207.649355 604.8311 Kinesin-like protein KIF11 OS=Homo sapiens OX=9606 GN=KIF11 PE=1 SV=2 8.31 3141.7 - 3.07E+06 - - - 1.4168 - 1.682 0.317 - 244 1 2 0 0.0017 10 0 0 0 1.23E+09 2.87E+08 - - - 2.8333 0.9994 221125_WJC_METTL3_EV_vs_WT_F01.14968.14968.2 0.25 18-Sep K.LVIIEGDLER[166.11].T "sp|P06753|TPM3_HUMAN,tr|A0A2R2Y2Q3|A0A2R2Y2Q3_HUMAN,tr|A0A087WWU8|A0A087WWU8_HUMAN,tr|J3KN67|J3KN67_HUMAN,tr|A0A494C0P6|A0A494C0P6_HUMAN" 5 1165.6582 1.17 3509 14968 2 1165.659043 583.8364 Tropomyosin alpha-3 chain OS=Homo sapiens OX=9606 GN=TPM3 PE=1 SV=2 4.14 3142.1 - 802674 - - - 0.7155 - 2.006 0.271 - 272 1 2 0 0.0008 10 0 0 0 3.73E+07 3.20E+07 - - - 2.9855 0.9995 221125_WJC_METTL3_EV_vs_WT_F01.14974.14974.2 0.024 18-Sep K.LVIIEGDLER.T "sp|P06753|TPM3_HUMAN,tr|A0A2R2Y2Q3|A0A2R2Y2Q3_HUMAN,tr|A0A087WWU8|A0A087WWU8_HUMAN,tr|J3KN67|J3KN67_HUMAN,tr|A0A494C0P6|A0A494C0P6_HUMAN" 5 1155.6499 1.17 3513 14974 2 1155.650552 578.8322 Tropomyosin alpha-3 chain OS=Homo sapiens OX=9606 GN=TPM3 PE=1 SV=2 4.14 3142.9 - 927098 - - - 0.5304 - 1.813 0.326 - 268.6 1 2 0 0.0006 10 0 0 0 3.75E+07 3.20E+07 - - - 3.1094 0.9465 221125_WJC_METTL3_EV_vs_WT_F01.14976.14976.2 0.00553 16-Aug R.AVFPSIVGR.P "sp|Q6S8J3|POTEE_HUMAN,sp|P63261|ACTG_HUMAN,sp|P68133|ACTS_HUMAN,sp|P62736|ACTA_HUMAN,sp|P68032|ACTC_HUMAN,sp|P60709|ACTB_HUMAN,sp|P63267|ACTH_HUMAN,sp|A5A3E0|POTEF_HUMAN,sp|P0CG38|POTEI_HUMAN,tr|A0A804GS07|A0A804GS07_HUMAN,tr|I3L3I0|I3L3I0_HUMAN,tr|G5E9R0|G5E9R0_HUMAN,tr|E7EVS6|E7EVS6_HUMAN,tr|B8ZZJ2|B8ZZJ2_HUMAN,tr|J3KT65|J3KT65_HUMAN,tr|I3L3R2|I3L3R2_HUMAN,tr|K7EM38|K7EM38_HUMAN,tr|F6QUT6|F6QUT6_HUMAN,tr|C9JTX5|C9JTX5_HUMAN,tr|A0A6Q8PH58|A0A6Q8PH58_HUMAN,tr|F6UVQ4|F6UVQ4_HUMAN,tr|F8WB63|F8WB63_HUMAN,tr|I3L1U9|I3L1U9_HUMAN,tr|A0A2R8Y793|A0A2R8Y793_HUMAN,tr|I3L4N8|I3L4N8_HUMAN,tr|C9JUM1|C9JUM1_HUMAN,tr|F8WCH0|F8WCH0_HUMAN,tr|C9JZR7|C9JZR7_HUMAN,tr|C9JFL5|C9JFL5_HUMAN,tr|A0A2R8YGF8|A0A2R8YGF8_HUMAN,tr|A6NL76|A6NL76_HUMAN" 31 944.5444 1.02 3515 14976 2 944.544151 473.2795 POTE ankyrin domain family member E OS=Homo sapiens OX=9606 GN=POTEE PE=2 SV=3 9.79 3143.1 - 1.40E+07 - - - -0.2117 - 1.454 0.311 - 245.8 1 1 0 -0.0002 9 0 0 0 5.65E+08 5.55E+08 - - - 2.4209 0.9997 221125_WJC_METTL3_EV_vs_WT_F01.14978.14978.2 0.000366 22-Nov K.AVASAAAALVLK.A sp|Q9Y490|TLN1_HUMAN 1 1083.6652 0.8 3517 14978 2 1083.666515 542.8399 Talin-1 OS=Homo sapiens OX=9606 GN=TLN1 PE=1 SV=3 8.8 3143.3 - 350444 - - - 1.2181 - 2.012 0.422 - 313.1 1 2 0 0.0013 12 0 0 0 1.54E+07 1.93E+07 - - - 3.997 0.9952 221125_WJC_METTL3_EV_vs_WT_F01.14983.14983.2 1.42 22-Oct K.AVASAAAALVLK[136.11].A sp|Q9Y490|TLN1_HUMAN 1 1091.6794 0.8 3520 14983 2 1091.679532 546.847 Talin-1 OS=Homo sapiens OX=9606 GN=TLN1 PE=1 SV=3 8.8 3143.8 - 622168 - - - 0.1255 - 1.785 0.096 - 203.4 2 2 0 0.0001 12 0 0 0 1.54E+07 1.93E+07 - - - 1.1401 0.9984 221125_WJC_METTL3_EV_vs_WT_F01.14987.14987.2 0.0958 12-Jul K.YIQELWR.K "sp|P61313|RL15_HUMAN,tr|A0A2R8YEM3|A0A2R8YEM3_HUMAN,tr|A0A2R8Y738|A0A2R8Y738_HUMAN,tr|E7EQV9|E7EQV9_HUMAN,tr|E7EX53|E7EX53_HUMAN,tr|E7ENU7|E7ENU7_HUMAN" 6 1006.5236 0.93 3522 14987 2 1006.524042 504.2691 60S ribosomal protein L15 OS=Homo sapiens OX=9606 GN=RPL15 PE=1 SV=2 6 3144.3 - 2.45E+06 - - - 0.4232 - 1.585 0.207 - 215.1 1 2 0 0.0004 7 0 0 0 4.96E+07 5.36E+07 - - - 2.0292 0.9997 221125_WJC_METTL3_EV_vs_WT_F01.14988.14988.2 0.000763 16-Aug R.AATLMMLGR[166.11].F "sp|Q99615|DNJC7_HUMAN,tr|A0A6I8PR93|A0A6I8PR93_HUMAN,tr|K7ESP1|K7ESP1_HUMAN,tr|A0A6I8PRZ0|A0A6I8PRZ0_HUMAN,tr|A0A6I8PLE7|A0A6I8PLE7_HUMAN,tr|K7EJE9|K7EJE9_HUMAN,tr|A0A6I8PR89|A0A6I8PR89_HUMAN,tr|A0A6I8PIK4|A0A6I8PIK4_HUMAN,tr|K7ELJ8|K7ELJ8_HUMAN,tr|K7EN19|K7EN19_HUMAN,tr|A0A6I8PUC2|A0A6I8PUC2_HUMAN,tr|A0A6I8PS32|A0A6I8PS32_HUMAN,tr|K7EJL5|K7EJL5_HUMAN,tr|K7EPP7|K7EPP7_HUMAN,tr|A0A6I8PUD4|A0A6I8PUD4_HUMAN,tr|K7EIH8|K7EIH8_HUMAN,tr|K7ER44|K7ER44_HUMAN,tr|A0A6I8PU73|A0A6I8PU73_HUMAN,tr|K7EK03|K7EK03_HUMAN,tr|K7EJV7|K7EJV7_HUMAN,tr|A0A6I8PU89|A0A6I8PU89_HUMAN" 21 972.5124 0.61 3523 14988 2 972.512818 487.2635 DnaJ homolog subfamily C member 7 OS=Homo sapiens OX=9606 GN=DNAJC7 PE=1 SV=2 9.79 3144.4 - 1.70E+06 - - - 0.4164 - 1.841 0.411 - 196.8 1 2 0 0.0004 9 0 0 0 3.00E+07 4.90E+07 - - - 3.8422 0.998 221125_WJC_METTL3_EV_vs_WT_F01.14990.14990.2 0.106 22-Aug K.VLPPPAGYVPIR[166.11].T sp|O75533|SF3B1_HUMAN 1 1287.7579 1.29 3525 14990 2 1287.759419 644.8862 Splicing factor 3B subunit 1 OS=Homo sapiens OX=9606 GN=SF3B1 PE=1 SV=3 8.72 3144.6 - 551359 - - - 1.2083 - 1.584 0.249 - 132.2 1 2 0 0.0016 12 0 0 0 4.65E+07 3.60E+07 - - - 2.0898 0.9969 221125_WJC_METTL3_EV_vs_WT_F01.14995.14995.2 0.125 12-Aug R.C[160.03]ILPFDK[136.11].E "sp|Q9GZT3|SLIRP_HUMAN,tr|H0YJW7|H0YJW7_HUMAN,tr|A0A087WUN7|A0A087WUN7_HUMAN,tr|G3V2S9|G3V2S9_HUMAN,tr|H0YJ40|H0YJ40_HUMAN,tr|G3V4X6|G3V4X6_HUMAN" 6 899.4666 1.93 3528 14995 2 899.466226 450.7406 "SRA stem-loop-interacting RNA-binding protein, mitochondrial OS=Homo sapiens OX=9606 GN=SLIRP PE=1 SV=1" 5.83 3145.3 - 710119 - - - -0.4436 - 1.296 0.217 - 264.8 1 2 0 -0.0004 7 0 0 0 1.38E+08 7.18E+07 - - - 1.4652 0.8854 221125_WJC_METTL3_EV_vs_WT_F01.15006.15006.2 5.31 16-Jun K.ILLLEAGPK[136.11].K "sp|Q9Y2Z9|COQ6_HUMAN,tr|G3V4A6|G3V4A6_HUMAN,tr|G3V2L5|G3V2L5_HUMAN,tr|G3V434|G3V434_HUMAN" 4 960.6099 1.28 3536 15006 2 960.609891 481.3122 "Ubiquinone biosynthesis monooxygenase COQ6, mitochondrial OS=Homo sapiens OX=9606 GN=COQ6 PE=1 SV=2" 6 3146.6 - 711113 - - - -0.0281 - 0.814 0.076 - 54.4 1 2 0 0 9 0 0 0 5.43E+07 4.25E+07 - - - -0.993 0.9998 221125_WJC_METTL3_EV_vs_WT_F01.15007.15007.2 0.00221 16-Oct R.ILDELTLC[160.03]K.S "sp|Q15323|K1H1_HUMAN,sp|O76011|KRT34_HUMAN,sp|O76013|KRT36_HUMAN,tr|A0A140TA62|A0A140TA62_HUMAN,tr|A0A140TA69|A0A140TA69_HUMAN" 5 1103.5896 54.91 3537 15007 2 1103.590212 552.8021 "Keratin, type I cuticular Ha1 OS=Homo sapiens OX=9606 GN=KRT31 PE=1 SV=3" 4.37 3146.8 - 491022 - - - 0.512 - 1.881 0.441 - 262.9 1 2 0 0.0006 9 0 0 0 1.55E+07 2.83E+05 - - - 4.1259 0.9984 221125_WJC_METTL3_EV_vs_WT_F01.15008.15008.2 0.18 14-Sep R.LGDLVWGK.L "sp|Q49A26|GLYR1_HUMAN,sp|Q9UBC3|DNM3B_HUMAN,tr|K7EQB2|K7EQB2_HUMAN,tr|K7ELL0|K7ELL0_HUMAN" 4 886.4913 0.87 3538 15008 2 886.490297 444.2529 Putative oxidoreductase GLYR1 OS=Homo sapiens OX=9606 GN=GLYR1 PE=1 SV=4 5.84 3146.8 - 620813 - - - -1.0784 - 1.691 0.208 - 233.9 1 2 0 -0.001 8 0 0 0 3.93E+07 4.54E+07 - - - 2.1613 0.9998 221125_WJC_METTL3_EV_vs_WT_F01.15010.15010.2 0.00331 18-Oct K.GGVADALLYR.A "sp|P14406|CX7A2_HUMAN,tr|D6RIE3|D6RIE3_HUMAN,tr|H0UI06|H0UI06_HUMAN,tr|D6RGV5|D6RGV5_HUMAN,tr|D6R9C3|D6R9C3_HUMAN" 5 1033.5556 1.25 3539 15010 2 1033.555982 517.7851 "Cytochrome c oxidase subunit 7A2, mitochondrial OS=Homo sapiens OX=9606 GN=COX7A2 PE=1 SV=1" 5.84 3147.1 - 1.42E+06 - - - 0.327 - 2.004 0.419 - 346.3 1 2 0 0.0003 10 0 0 0 4.23E+07 3.37E+07 - - - 4.076 0.9988 221125_WJC_METTL3_EV_vs_WT_F01.15018.15018.2 0.228 14-Jul R.GLVVPVIR.N sp|P36957|ODO2_HUMAN 1 851.5593 1.54 3544 15018 2 851.560209 426.7869 "Dihydrolipoyllysine-residue succinyltransferase component of 2-oxoglutarate dehydrogenase complex, mitochondrial OS=Homo sapiens OX=9606 GN=DLST PE=1 SV=4" 9.75 3147.9 - 3.75E+06 - - - 1.0992 - 1.667 0.262 - 233.5 1 2 0 0.0009 8 0 0 0 8.75E+07 5.68E+07 - - - 2.5171 0.9648 221125_WJC_METTL3_EV_vs_WT_F01.15030.15030.2 0.0126 16-Aug A.GGVMTVLIK[136.11].R "sp|P11142|HSP7C_HUMAN,tr|E9PNE6|E9PNE6_HUMAN,tr|A8K7Q2|A8K7Q2_HUMAN,tr|E9PKE3|E9PKE3_HUMAN" 4 924.5558 0.12 3553 15030 2 924.555945 463.2852 Heat shock cognate 71 kDa protein OS=Homo sapiens OX=9606 GN=HSPA8 PE=1 SV=1 8.75 3149.4 - 3.59E+06 - - - 0.185 - 1.506 0.355 - 190 1 1 0 0.0002 9 0 0 0 1.40E+07 1.13E+08 - - - 2.8476 0.9791 221125_WJC_METTL3_EV_vs_WT_F01.15031.15031.2 3.28 14-May R.GLVVPVIR[166.11].N sp|P36957|ODO2_HUMAN 1 861.5675 1.54 3554 15031 2 861.567608 431.791 "Dihydrolipoyllysine-residue succinyltransferase component of 2-oxoglutarate dehydrogenase complex, mitochondrial OS=Homo sapiens OX=9606 GN=DLST PE=1 SV=4" 9.75 3149.4 - 2.40E+06 - - - 0.0754 - 1.343 0.027 - 128.7 1 2 0 0.0001 8 0 0 0 8.75E+07 5.68E+07 - - - 0.1298 0.992 221125_WJC_METTL3_EV_vs_WT_F01.15036.15036.2 0.0706 16-Sep R.LYQVEYAFK[136.11].A "sp|P60900|PSA6_HUMAN,tr|G3V5Z7|G3V5Z7_HUMAN,tr|G3V295|G3V295_HUMAN,tr|G3V3I1|G3V3I1_HUMAN,tr|G3V3U4|G3V3U4_HUMAN" 5 1167.6056 0.82 3557 15036 2 1167.610506 584.8101 Proteasome subunit alpha type-6 OS=Homo sapiens OX=9606 GN=PSMA6 PE=1 SV=1 6 3150 - 463948 - - - 4.2352 - 1.451 0.347 - 224 1 2 0 0.0049 9 0 0 0 1.67E+07 2.05E+07 - - - 2.6793 0.9994 221125_WJC_METTL3_EV_vs_WT_F01.15053.15053.2 0.000217 18-Sep K.AGVDPLVPLR.S "sp|Q9UJ70|NAGK_HUMAN,tr|H0YEB7|H0YEB7_HUMAN,tr|C9JEV6|C9JEV6_HUMAN,tr|H0YE82|H0YE82_HUMAN,tr|H7C3G9|H7C3G9_HUMAN,tr|H7C1L7|H7C1L7_HUMAN" 6 1035.6077 1.59 3568 15053 2 1035.609885 518.8111 N-acetyl-D-glucosamine kinase OS=Homo sapiens OX=9606 GN=NAGK PE=1 SV=4 5.88 3152.2 - 367051 - - - 2.1292 - 1.77 0.424 - 259.8 1 2 0 0.0022 10 0 0 0 1.09E+07 6.86E+06 - - - 3.7657 0.9952 221125_WJC_METTL3_EV_vs_WT_F01.15060.15060.2 0.0927 12-Jul K.DDLVLLK[136.11].R "sp|P56962|STX17_HUMAN,tr|E9PIC2|E9PIC2_HUMAN" 2 822.4942 0.76 3573 15060 2 822.495534 412.2544 Syntaxin-17 OS=Homo sapiens OX=9606 GN=STX17 PE=1 SV=2 4.21 3153.1 - 178080 - - - 1.5976 - 1.433 0.188 - 153.7 1 2 0 0.0013 7 0 0 0 6.00E+06 7.87E+06 - - - 1.5691 0.9924 221125_WJC_METTL3_EV_vs_WT_F01.15062.15062.2 0.463 12-Jul K.DDLVLLK.R "sp|P56962|STX17_HUMAN,tr|E9PIC2|E9PIC2_HUMAN" 2 814.48 0.81 3575 15062 2 814.481733 408.2473 Syntaxin-17 OS=Homo sapiens OX=9606 GN=STX17 PE=1 SV=2 4.21 3153.3 - 105381 - - - 2.1032 - 1.548 0.14 - 147.1 1 2 0 0.0017 7 0 0 0 5.89E+06 7.29E+06 - - - 1.459 0.9929 221125_WJC_METTL3_EV_vs_WT_F01.15066.15066.2 0.0492 18-Aug R.LGTVLPVIEK[136.11].E sp|O75691|UTP20_HUMAN 1 1075.6732 35.15 3577 15066 2 1075.675966 538.8439 Small subunit processome component 20 homolog OS=Homo sapiens OX=9606 GN=UTP20 PE=1 SV=3 6 3153.9 - 239756 - - - 2.5277 - 1.439 0.226 - 170.1 1 2 0 0.0027 10 0 0 0 1.84E+08 5.24E+06 - - - 1.7253 0.9901 221125_WJC_METTL3_EV_vs_WT_F01.15076.15076.2 0.11 16-May R.LIDGIVLTK.F sp|P08240|SRPRA_HUMAN 1 970.6063 1.02 3585 15076 2 970.607638 486.3104 Signal recognition particle receptor subunit alpha OS=Homo sapiens OX=9606 GN=SRPRA PE=1 SV=2 5.84 3155.1 - 1.14E+06 - - - 1.396 - 1.054 0.275 - 45.8 4 2 0 0.0014 9 0 0 0 3.17E+07 3.09E+07 - - - 0.9549 0.9831 221125_WJC_METTL3_EV_vs_WT_F01.15078.15078.2 0.36 14-Jun R.LNISDPLR.L tr|A0A1W2PRW1|A0A1W2PRW1_HUMAN 1 926.5185 0.97 3587 15078 2 926.519635 464.2665 "N-acetyllactosaminide beta-1,6-N-acetylglucosaminyl-transferase OS=Homo sapiens OX=9606 GN=GCNT2 PE=1 SV=1" 5.84 3155.3 - 668176 - - - 1.1916 - 1.312 0.107 - 100.5 2 2 0 0.0011 8 0 0 0 1.59E+07 1.65E+07 - - - 0.5155 0.9851 221125_WJC_METTL3_EV_vs_WT_F01.15079.15079.2 0.00101 14-Aug R.LLEC[160.03]YFTR[166.11].S "sp|Q7Z6Z7|HUWE1_HUMAN,tr|H0Y659|H0Y659_HUMAN" 2 1110.5407 1.53 3588 15079 2 1110.542889 556.2776 E3 ubiquitin-protein ligase HUWE1 OS=Homo sapiens OX=9606 GN=HUWE1 PE=1 SV=3 5.99 3155.4 - 291441 - - - 1.9387 - 1.422 0.107 - 248.1 1 2 0 0.0022 8 0 0 0 1.29E+07 8.44E+06 - - - 0.8924 0.9984 221125_WJC_METTL3_EV_vs_WT_F01.15080.15080.2 0.047 16-Aug K.LITWSPVC[160.03]R.N "sp|P07203|GPX1_HUMAN,tr|A0A2R8Y6B6|A0A2R8Y6B6_HUMAN" 2 1130.5907 1.02 3589 15080 2 1130.592822 566.3026 Glutathione peroxidase 1 OS=Homo sapiens OX=9606 GN=GPX1 PE=1 SV=4 8.25 3155.6 - 264041 - - - 1.9211 - 1.794 0.259 - 183.1 1 2 0 0.0022 9 0 0 0 8.72E+06 8.52E+06 - - - 2.6441 0.9997 221125_WJC_METTL3_EV_vs_WT_F01.15084.15084.2 0.00143 14-Aug K.YYVLNALK[136.11].H "sp|Q6P2Q9|PRP8_HUMAN,tr|I3L0J9|I3L0J9_HUMAN" 2 990.563 8.57 3592 15084 2 990.563804 496.2888 Pre-mRNA-processing-splicing factor 8 OS=Homo sapiens OX=9606 GN=PRPF8 PE=1 SV=2 8.5 3156.1 - 1.63E+06 - - - 0.844 - 1.445 0.503 - 158.2 1 2 0 0.0008 8 0 0 0 2.91E+08 3.39E+07 - - - 3.8661 0.9894 221125_WJC_METTL3_EV_vs_WT_F01.15086.15086.2 0.614 14-Jul R.LLPEQLIK.E "sp|Q92621|NU205_HUMAN,sp|Q8TBZ9|TEX47_HUMAN" 2 952.5957 1.28 3593 15086 2 952.597134 477.3051 Nuclear pore complex protein Nup205 OS=Homo sapiens OX=9606 GN=NUP205 PE=1 SV=3 6 3156.4 - 1.43E+06 - - - 1.4865 - 1.088 0.223 - 116.5 1 2 0 0.0014 8 0 0 0 5.43E+07 4.25E+07 - - - 0.942 0.9994 221125_WJC_METTL3_EV_vs_WT_F01.15089.15089.2 0.00269 16-Sep K.YMTDGMLLR.E "sp|Q14562|DHX8_HUMAN,sp|O60231|DHX16_HUMAN,sp|O43143|DHX15_HUMAN,tr|A0A140T947|A0A140T947_HUMAN,tr|F5H658|F5H658_HUMAN" 5 1098.5202 1.09 3596 15089 2 1098.522429 550.2674 ATP-dependent RNA helicase DHX8 OS=Homo sapiens OX=9606 GN=DHX8 PE=1 SV=1 5.84 3156.7 - 505356 - - - 2.0409 - 1.579 0.462 - 278.6 1 2 0 0.0022 9 0 0 0 6.95E+07 6.40E+07 - - - 3.7742 0.9891 221125_WJC_METTL3_EV_vs_WT_F01.15094.15094.2 0.375 12-Jul K.DFLLTAR.R "sp|P63173|RL38_HUMAN,tr|J3KT73|J3KT73_HUMAN,tr|J3QL01|J3QL01_HUMAN,tr|J3KSP2|J3KSP2_HUMAN" 4 834.46 1.07 3599 15094 2 834.461148 418.2373 60S ribosomal protein L38 OS=Homo sapiens OX=9606 GN=RPL38 PE=1 SV=2 5.84 3157.4 - 4.94E+07 - - - 1.4321 - 1.33 0.13 - 238.6 1 2 0 0.0012 7 0 0 0 8.68E+08 8.10E+08 - - - 0.9044 0.946 221125_WJC_METTL3_EV_vs_WT_F01.15106.15106.2 0.498 14-Jun R.FAPPLVIK[136.11].E sp|P04181|OAT_HUMAN 1 891.5673 7.81 3609 15106 2 891.567241 446.7909 "Ornithine aminotransferase, mitochondrial OS=Homo sapiens OX=9606 GN=OAT PE=1 SV=1" 8.75 3158.9 - 759637 - - - -0.0942 - 0.843 0.133 - 88.5 1 2 0 -0.0001 8 0 0 0 1.69E+08 2.16E+07 - - - -0.4918 0.9986 221125_WJC_METTL3_EV_vs_WT_F01.15107.15107.2 0.116 16-Jul R.LIDGIVLTK[136.11].F sp|P08240|SRPRA_HUMAN 1 978.6205 1.05 3610 15107 2 978.621198 490.3175 Signal recognition particle receptor subunit alpha OS=Homo sapiens OX=9606 GN=SRPRA PE=1 SV=2 5.84 3158.9 - 1.98E+06 - - - 0.7306 - 1.284 0.332 - 97.3 1 2 0 0.0007 9 0 0 0 3.16E+07 3.00E+07 - - - 2.2161 0.988 221125_WJC_METTL3_EV_vs_WT_F01.15108.15108.2 0.384 16-Jun K.FVPLLPGNR.S sp|P78527|PRKDC_HUMAN 1 1011.5866 0.59 3611 15108 2 1011.587187 506.8006 DNA-dependent protein kinase catalytic subunit OS=Homo sapiens OX=9606 GN=PRKDC PE=1 SV=3 9.75 3159 - 869044 - - - 0.6287 - 1.146 0.155 - 117.1 1 2 0 0.0006 9 0 0 0 1.53E+07 2.58E+07 - - - 0.5799 0.973 221125_WJC_METTL3_EV_vs_WT_F01.15110.15110.2 0.137 12-Jul K.LVIDVIR.Y "sp|Q14683|SMC1A_HUMAN,tr|G8JLG1|G8JLG1_HUMAN,tr|A0A6Q8PHC3|A0A6Q8PHC3_HUMAN" 3 826.5276 0.6 3613 15110 2 826.528816 414.2711 Structural maintenance of chromosomes protein 1A OS=Homo sapiens OX=9606 GN=SMC1A PE=1 SV=2 5.84 3159.2 - 541427 - - - 1.424 - 1.395 0.025 - 169.1 1 2 0 0.0012 7 0 0 0 1.45E+08 2.43E+08 - - - 0.2801 0.994 221125_WJC_METTL3_EV_vs_WT_F01.15111.15111.2 0.0147 16-Sep R.VLGMTLIQK.C sp|Q04760|LGUL_HUMAN 1 1001.5943 1 3614 15111 2 1001.596334 501.8044 Lactoylglutathione lyase OS=Homo sapiens OX=9606 GN=GLO1 PE=1 SV=4 8.72 3159.4 - 421449 - - - 1.9928 - 1.633 0.152 - 177.3 1 2 0 0.002 9 0 0 0 3.58E+07 3.60E+07 - - - 1.5819 0.9995 221125_WJC_METTL3_EV_vs_WT_F01.15116.15116.2 0.00644 16-Oct R.LFEGNALLR.R "sp|P46781|RS9_HUMAN,tr|C9JM19|C9JM19_HUMAN,tr|B5MCT8|B5MCT8_HUMAN" 3 1031.5764 1.14 3617 15116 2 1031.577652 516.7955 40S ribosomal protein S9 OS=Homo sapiens OX=9606 GN=RPS9 PE=1 SV=3 6 3160 - 807953 - - - 1.2331 - 1.793 0.377 - 352.9 1 2 0 0.0013 9 0 0 0 8.08E+08 7.09E+08 - - - 3.5143 0.9969 221125_WJC_METTL3_EV_vs_WT_F01.15118.15118.2 0.246 16-Jul R.VLGMTLIQK[136.11].C sp|Q04760|LGUL_HUMAN 1 1009.6085 1 3619 15118 2 1009.609559 505.8115 Lactoylglutathione lyase OS=Homo sapiens OX=9606 GN=GLO1 PE=1 SV=4 8.72 3160.3 - 937322 - - - 1.0113 - 1.517 0.193 - 130.8 1 2 0 0.001 9 0 0 0 3.58E+07 3.60E+07 - - - 1.6718 0.9991 221125_WJC_METTL3_EV_vs_WT_F01.15119.15119.2 0.0479 16-Aug R.VPLDPLIGK[136.11].N sp|P53384|NUBP1_HUMAN 1 958.5943 1.67 3620 15119 2 958.59476 480.3044 Cytosolic Fe-S cluster assembly factor NUBP1 OS=Homo sapiens OX=9606 GN=NUBP1 PE=1 SV=2 5.81 3160.4 - 708442 - - - 0.5133 - 1.544 0.299 - 163 1 2 0 0.0005 9 0 0 0 4.97E+07 2.97E+07 - - - 2.5059 0.9231 221125_WJC_METTL3_EV_vs_WT_F01.15124.15124.2 5.6 16-Jun R.VVLGEFGVR[166.11].N "sp|O15160|RPAC1_HUMAN,tr|A0A2R8YEZ4|A0A2R8YEZ4_HUMAN,tr|H0Y723|H0Y723_HUMAN,tr|E7EQB9|E7EQB9_HUMAN,tr|A0A2R8Y5D3|A0A2R8Y5D3_HUMAN,tr|A0A2R8Y8D6|A0A2R8Y8D6_HUMAN" 6 984.5632 0.31 3624 15124 2 984.564568 493.2889 DNA-directed RNA polymerases I and III subunit RPAC1 OS=Homo sapiens OX=9606 GN=POLR1C PE=1 SV=1 5.97 3161.1 - 907692 - - - 1.4037 - 1.165 0.042 - 85.4 3 2 0 0.0014 9 0 0 0 9.03E+07 2.94E+08 - - - -0.4205 0.9992 221125_WJC_METTL3_EV_vs_WT_F01.15126.15126.2 0.0164 12-Jul K.FVSELWK[136.11].D sp|P35579|MYH9_HUMAN 1 915.4946 0.8 3625 15126 2 915.495272 458.7546 Myosin-9 OS=Homo sapiens OX=9606 GN=MYH9 PE=1 SV=4 6 3161.3 - 3.09E+06 - - - 0.7843 - 1.386 0.356 - 137.3 1 2 0 0.0007 7 0 0 0 1.35E+08 1.68E+08 - - - 2.7045 0.9994 221125_WJC_METTL3_EV_vs_WT_F01.15128.15128.2 0.0222 16-Oct K.LLPDTILEK[136.11].L "sp|Q9UMY1|NOL7_HUMAN,tr|H7C2B1|H7C2B1_HUMAN" 2 1048.626 0.57 3627 15128 2 1048.625627 525.3203 Nucleolar protein 7 OS=Homo sapiens OX=9606 GN=NOL7 PE=1 SV=2 4.37 3161.5 - 309154 - - - -0.3195 - 1.651 0.32 - 229.6 1 2 0 -0.0003 9 0 0 0 4.99E+07 8.73E+07 - - - 2.8549 0.9937 221125_WJC_METTL3_EV_vs_WT_F01.15132.15132.2 0.0791 14-Jul K.FVADGIFK.A "sp|P23396|RS3_HUMAN,tr|H0YEU2|H0YEU2_HUMAN,tr|E9PL09|E9PL09_HUMAN,tr|E9PK82|E9PK82_HUMAN,tr|H0YES8|H0YES8_HUMAN,tr|F2Z2S8|F2Z2S8_HUMAN,tr|H0YCJ7|H0YCJ7_HUMAN,tr|E9PQ96|E9PQ96_HUMAN,tr|E9PJH4|E9PJH4_HUMAN,tr|E9PQX2|E9PQX2_HUMAN,tr|E9PPU1|E9PPU1_HUMAN" 11 895.4804 0.68 3629 15132 2 895.48192 448.7475 40S ribosomal protein S3 OS=Homo sapiens OX=9606 GN=RPS3 PE=1 SV=2 5.84 3162 - 1.60E+06 - - - 1.7488 - 1.126 0.275 - 105.1 1 2 0 0.0016 8 0 0 0 2.35E+09 3.44E+09 - - - 1.4296 0.9972 221125_WJC_METTL3_EV_vs_WT_F01.15134.15134.2 0.695 14-Jun K.FVADGIFK[136.11].A "sp|P23396|RS3_HUMAN,tr|H0YEU2|H0YEU2_HUMAN,tr|E9PL09|E9PL09_HUMAN,tr|E9PK82|E9PK82_HUMAN,tr|H0YES8|H0YES8_HUMAN,tr|F2Z2S8|F2Z2S8_HUMAN,tr|H0YCJ7|H0YCJ7_HUMAN,tr|E9PQ96|E9PQ96_HUMAN,tr|E9PJH4|E9PJH4_HUMAN,tr|E9PQX2|E9PQX2_HUMAN,tr|E9PPU1|E9PPU1_HUMAN" 11 903.4946 0.68 3631 15134 2 903.494689 452.7546 40S ribosomal protein S3 OS=Homo sapiens OX=9606 GN=RPS3 PE=1 SV=2 5.84 3162.1 - 3.05E+06 - - - 0.1494 - 1.267 0.243 - 83 1 2 0 0.0001 8 0 0 0 2.35E+09 3.44E+09 - - - 1.5495 0.9994 221125_WJC_METTL3_EV_vs_WT_F01.15135.15135.2 0.0264 16-Sep R.VPLDPLIGK.N sp|P53384|NUBP1_HUMAN 1 950.5801 1.62 3632 15135 2 950.580633 476.2973 Cytosolic Fe-S cluster assembly factor NUBP1 OS=Homo sapiens OX=9606 GN=NUBP1 PE=1 SV=2 5.81 3162.2 - 1.20E+06 - - - 0.5944 - 1.62 0.351 - 295.4 1 2 0 0.0006 9 0 0 0 4.97E+07 3.06E+07 - - - 3.029 0.9998 221125_WJC_METTL3_EV_vs_WT_F01.15141.15141.2 0.000124 22-Nov K.VLPPPAGYVPIR.T sp|O75533|SF3B1_HUMAN 1 1277.7496 1.29 3637 15141 2 1277.750361 639.8821 Splicing factor 3B subunit 1 OS=Homo sapiens OX=9606 GN=SF3B1 PE=1 SV=3 8.72 3162.9 - 1.08E+06 - - - 0.6011 - 1.989 0.433 - 252.8 1 2 0 0.0008 12 0 0 0 1.02E+08 7.89E+07 - - - 4.0482 0.9993 221125_WJC_METTL3_EV_vs_WT_F01.15145.15145.2 0.0517 16-Aug R.LIVNVNDLR[166.11].R sp|P25205|MCM3_HUMAN 1 1064.6218 0.54 3640 15145 2 1064.622189 533.3182 DNA replication licensing factor MCM3 OS=Homo sapiens OX=9606 GN=MCM3 PE=1 SV=3 5.84 3163.4 - 451878 - - - 0.3992 - 1.562 0.321 - 196.7 1 2 0 0.0004 9 0 0 0 2.98E+07 5.50E+07 - - - 2.702 0.9964 221125_WJC_METTL3_EV_vs_WT_F01.15146.15146.2 0.373 18-Sep R.ELLQESALIR.K "sp|Q12931|TRAP1_HUMAN,tr|I3L0K7|I3L0K7_HUMAN,tr|I3L239|I3L239_HUMAN" 3 1170.6608 2.06 3641 15146 2 1170.66226 586.3377 "Heat shock protein 75 kDa, mitochondrial OS=Homo sapiens OX=9606 GN=TRAP1 PE=1 SV=3" 4.53 3163.5 - 396813 - - - 1.2147 - 1.475 0.205 - 309.5 1 2 0 0.0014 10 0 0 0 5.52E+07 2.67E+07 - - - 1.6395 0.9997 221125_WJC_METTL3_EV_vs_WT_F01.15148.15148.2 0.0128 18-Sep R.ELLQESALIR[166.11].K "sp|Q12931|TRAP1_HUMAN,tr|I3L0K7|I3L0K7_HUMAN,tr|I3L239|I3L239_HUMAN" 3 1180.6691 2.06 3643 15148 2 1180.669605 591.3418 "Heat shock protein 75 kDa, mitochondrial OS=Homo sapiens OX=9606 GN=TRAP1 PE=1 SV=3" 4.53 3163.8 - 212805 - - - 0.4209 - 2.062 0.332 - 338 1 2 0 0.0005 10 0 0 0 5.52E+07 2.67E+07 - - - 3.513 0.9973 221125_WJC_METTL3_EV_vs_WT_F01.15153.15153.2 1.97 14-Jul K.TAVLTLIR.E "sp|O75410|TACC1_HUMAN,tr|E7EVI4|E7EVI4_HUMAN,tr|B4E3H6|B4E3H6_HUMAN,tr|E5RFM9|E5RFM9_HUMAN,tr|R4GMT7|R4GMT7_HUMAN,tr|H0YAY0|H0YAY0_HUMAN,tr|H0YBT8|H0YBT8_HUMAN,tr|E7ET87|E7ET87_HUMAN" 8 885.5648 1.09 3645 15153 2 885.564942 443.7897 Transforming acidic coiled-coil-containing protein 1 OS=Homo sapiens OX=9606 GN=TACC1 PE=1 SV=2 9.41 3164.4 - 3.41E+06 - - - 0.2134 - 1.676 0.133 - 273.4 1 2 0 0.0002 8 0 0 0 1.66E+08 1.52E+08 - - - 1.5807 0.998 221125_WJC_METTL3_EV_vs_WT_F01.15154.15154.2 0.319 14-Aug K.MLLSLPEK[136.11].V "sp|Q8N163|CCAR2_HUMAN,tr|A0A087X2B6|A0A087X2B6_HUMAN,tr|H0YB24|H0YB24_HUMAN,tr|G3V119|G3V119_HUMAN" 4 937.5398 1.01 3646 15154 2 937.540765 469.7772 Cell cycle and apoptosis regulator protein 2 OS=Homo sapiens OX=9606 GN=CCAR2 PE=1 SV=2 5.75 3164.5 - 809091 - - - 1.04 - 1.444 0.254 - 211.4 1 2 0 0.001 8 0 0 0 1.83E+07 1.81E+07 - - - 2.0249 0.9992 221125_WJC_METTL3_EV_vs_WT_F01.15155.15155.2 0.0135 14-Aug K.VFNLGVYR.R "sp|O60825|F262_HUMAN,tr|F6RAZ1|F6RAZ1_HUMAN" 2 966.5287 2.72 3647 15155 2 966.530037 484.2716 "6-phosphofructo-2-kinase\fructose-2,6-bisphosphatase 2 OS=Homo sapiens OX=9606 GN=PFKFB2 PE=1 SV=2" 8.72 3164.6 - 225099 - - - 1.3823 - 1.663 0.33 - 193.3 1 2 0 0.0013 8 0 0 0 9.46E+07 3.47E+07 - - - 3.0119 0.9951 221125_WJC_METTL3_EV_vs_WT_F01.15156.15156.2 0.0342 16-Jun R.LLYEELYNK[136.11].T sp|O75330|HMMR_HUMAN 1 1191.6267 0.05 3648 15156 2 1191.624574 596.8206 Hyaluronan mediated motility receptor OS=Homo sapiens OX=9606 GN=HMMR PE=1 SV=2 4.53 3164.8 - 220330 - - - -1.7766 - 1.196 0.273 - 81.2 1 2 0 -0.0021 9 0 0 0 4.23E+06 8.49E+07 - - - 1.5745 0.9961 221125_WJC_METTL3_EV_vs_WT_F01.15168.15168.2 0.142 14-Jun R.IAVPVLVR.D sp|P52952|NKX25_HUMAN 1 865.5749 2.17 3655 15168 2 865.573225 433.7947 Homeobox protein Nkx-2.5 OS=Homo sapiens OX=9606 GN=NKX2-5 PE=1 SV=1 9.75 3166.4 - 459774 - - - -1.9617 - 1.25 0.288 - 121.7 1 2 0 -0.0017 8 0 0 0 3.32E+07 1.54E+07 - - - 1.8406 0.9979 221125_WJC_METTL3_EV_vs_WT_F01.15169.15169.2 0.163 12-Jun K.AFLFVNK[136.11].G sp|Q8N0X7|SPART_HUMAN 1 845.4891 1.1 3656 15169 2 845.488658 423.7518 Spartin OS=Homo sapiens OX=9606 GN=SPART PE=1 SV=1 8.8 3166.4 - 9.96E+06 - - - -0.4932 - 1.303 0.256 - 151.1 1 2 0 -0.0004 7 0 0 0 2.06E+08 1.88E+08 - - - 1.7703 0.9997 221125_WJC_METTL3_EV_vs_WT_F01.15171.15171.2 0.000568 16-Sep R.AMAVLESLR[166.11].V "sp|P47897|SYQ_HUMAN,tr|B4DDN1|B4DDN1_HUMAN,tr|H7C0R3|H7C0R3_HUMAN,tr|A0A1B0GVU9|A0A1B0GVU9_HUMAN" 4 998.5458 0.99 3658 15171 2 998.54688 500.2802 Glutamine--tRNA ligase OS=Homo sapiens OX=9606 GN=QARS1 PE=1 SV=1 6.05 3166.5 - 1.24E+06 - - - 1.0595 - 1.946 0.402 - 435.3 1 2 0 0.0011 9 0 0 0 3.07E+07 3.11E+07 - - - 3.936 0.9878 221125_WJC_METTL3_EV_vs_WT_F01.15174.15174.2 0.245 14-Aug R.TVETLLLR.F "sp|Q9H845|ACAD9_HUMAN,tr|A0A7P0T871|A0A7P0T871_HUMAN,tr|A0A7P0T7Z1|A0A7P0T7Z1_HUMAN,tr|A0A7P0T8U3|A0A7P0T8U3_HUMAN,tr|Q9H9W4|Q9H9W4_HUMAN,tr|H0Y8Z9|H0Y8Z9_HUMAN" 6 943.5702 0.16 3659 15174 2 943.571811 472.7924 "Complex I assembly factor ACAD9, mitochondrial OS=Homo sapiens OX=9606 GN=ACAD9 PE=1 SV=1" 5.66 3166.9 - 547753 - - - 1.6734 - 1.256 0.161 - 218 1 2 0 0.0016 8 0 0 0 3.90E+07 2.48E+08 - - - 0.9171 0.9793 221125_WJC_METTL3_EV_vs_WT_F01.15178.15178.2 0.479 16-Jun K.MYATIYELK.E "sp|P80188|NGAL_HUMAN,tr|X6R8F3|X6R8F3_HUMAN" 2 1130.5682 28.8 3663 15178 2 1130.567892 566.2914 Neutrophil gelatinase-associated lipocalin OS=Homo sapiens OX=9606 GN=LCN2 PE=1 SV=2 5.75 3167.3 - 322178 - - - -0.2574 - 0.896 0.191 - 62.6 1 2 0 -0.0003 9 0 0 0 4.45E+06 1.55E+05 - - - 0.1339 0.9972 221125_WJC_METTL3_EV_vs_WT_F01.15188.15188.2 0.433 14-Aug K.NLYIISVK[136.11].G "sp|P62829|RL23_HUMAN,tr|J3KT29|J3KT29_HUMAN,tr|B9ZVP7|B9ZVP7_HUMAN,tr|C9JD32|C9JD32_HUMAN" 4 956.5786 1 3669 15188 2 956.577719 479.2966 60S ribosomal protein L23 OS=Homo sapiens OX=9606 GN=RPL23 PE=1 SV=1 8.59 3168.5 - 2.10E+06 - - - -0.9398 - 1.538 0.177 - 273.4 1 2 0 -0.0009 8 0 0 0 5.44E+09 5.42E+09 - - - 1.6464 0.9949 221125_WJC_METTL3_EV_vs_WT_F01.15189.15189.2 0.00137 14-Jul K.NLYIISVK.G "sp|P62829|RL23_HUMAN,tr|J3KT29|J3KT29_HUMAN,tr|B9ZVP7|B9ZVP7_HUMAN,tr|C9JD32|C9JD32_HUMAN" 4 948.5644 1 3670 15189 2 948.563728 475.2895 60S ribosomal protein L23 OS=Homo sapiens OX=9606 GN=RPL23 PE=1 SV=1 8.59 3168.6 - 1.58E+06 - - - -0.7274 - 1.375 0.155 - 168 1 2 0 -0.0007 8 0 0 0 5.44E+09 5.42E+09 - - - 1.1461 0.9991 221125_WJC_METTL3_EV_vs_WT_F01.15190.15190.2 0.00137 18-Oct K.LLANMVYQYK.G "sp|P28074|PSB5_HUMAN,tr|H0YJM8|H0YJM8_HUMAN" 2 1241.6478 0.65 3671 15190 2 1241.64301 621.8312 Proteasome subunit beta type-5 OS=Homo sapiens OX=9606 GN=PSMB5 PE=1 SV=3 8.5 3168.8 - 690842 - - - -3.8819 - 2.021 0.555 - 333.2 1 2 0 -0.0048 10 0 0 0 2.71E+07 4.17E+07 - - - 5.1027 0.9998 221125_WJC_METTL3_EV_vs_WT_F01.15196.15196.2 3.80E-05 20-Nov R.VIGTLLGTVDK.H "sp|O00303|EIF3F_HUMAN,tr|A0A1W2PP79|A0A1W2PP79_HUMAN,tr|H0YDT6|H0YDT6_HUMAN,tr|A0A7I2YQA0|A0A7I2YQA0_HUMAN" 4 1114.6598 1.12 3675 15196 2 1114.658776 558.3372 Eukaryotic translation initiation factor 3 subunit F OS=Homo sapiens OX=9606 GN=EIF3F PE=1 SV=1 5.81 3169.5 - 922416 - - - -0.8962 - 2.147 0.433 - 245.2 1 2 0 -0.001 11 0 0 0 1.22E+08 1.09E+08 - - - 4.3058 0.9983 221125_WJC_METTL3_EV_vs_WT_F01.15197.15197.2 0.000423 20-Oct K.WEGLVYAPPGK.E "sp|Q9Y2W1|TR150_HUMAN,tr|A0A3B3ITZ9|A0A3B3ITZ9_HUMAN" 2 1215.6288 2.09 3676 15197 2 1215.632599 608.8217 Thyroid hormone receptor-associated protein 3 OS=Homo sapiens OX=9606 GN=THRAP3 PE=1 SV=2 6 3169.6 - 310080 - - - 3.1177 - 1.756 0.391 - 250.5 1 2 0 0.0038 11 0 0 0 3.32E+07 1.59E+07 - - - 3.4509 0.9998 221125_WJC_METTL3_EV_vs_WT_F01.15201.15201.2 0.000502 13/20 R.VIGTLLGTVDK[136.11].H "sp|O00303|EIF3F_HUMAN,tr|A0A1W2PP79|A0A1W2PP79_HUMAN,tr|H0YDT6|H0YDT6_HUMAN,tr|A0A7I2YQA0|A0A7I2YQA0_HUMAN" 4 1122.674 1.12 3678 15201 2 1122.673128 562.3443 Eukaryotic translation initiation factor 3 subunit F OS=Homo sapiens OX=9606 GN=EIF3F PE=1 SV=1 5.81 3170.1 - 1.22E+06 - - - -0.7544 - 2.498 0.385 - 428.7 1 2 0 -0.0008 11 0 0 0 1.22E+08 1.09E+08 - - - 4.361 0.9994 221125_WJC_METTL3_EV_vs_WT_F01.15202.15202.2 0.00174 16-Aug R.AMAVLESLR.V "sp|P47897|SYQ_HUMAN,tr|B4DDN1|B4DDN1_HUMAN,tr|H7C0R3|H7C0R3_HUMAN,tr|A0A1B0GVU9|A0A1B0GVU9_HUMAN" 4 988.5376 0.99 3679 15202 2 988.538441 495.2761 Glutamine--tRNA ligase OS=Homo sapiens OX=9606 GN=QARS1 PE=1 SV=1 6.05 3170.2 - 2.14E+06 - - - 0.8993 - 1.509 0.39 - 145.7 1 2 0 0.0009 9 0 0 0 3.07E+07 3.11E+07 - - - 3.1116 0.9943 221125_WJC_METTL3_EV_vs_WT_F01.15209.15209.2 0.0456 16-Jul R.FFMGNQVLK[136.11].V sp|P13010|XRCC5_HUMAN 1 1090.5725 0.96 3684 15209 2 1090.568737 546.2935 X-ray repair cross-complementing protein 5 OS=Homo sapiens OX=9606 GN=XRCC5 PE=1 SV=3 8.75 3171 - 447907 - - - -3.4386 - 1.165 0.399 - 96.5 1 2 0 -0.0037 9 0 0 0 1.23E+08 1.29E+08 - - - 2.4287 0.7949 221125_WJC_METTL3_EV_vs_WT_F01.15210.15210.2 0.174 16-Jul R.FFMGNQVLK.V sp|P13010|XRCC5_HUMAN 1 1082.5583 0.96 3685 15210 2 1082.549727 542.2864 X-ray repair cross-complementing protein 5 OS=Homo sapiens OX=9606 GN=XRCC5 PE=1 SV=3 8.75 3171.2 - 308729 - - - -7.9072 - 1.26 0.279 - 89.7 1 2 0 -0.0086 9 0 0 0 1.23E+08 1.29E+08 - - - 1.7676 0.9996 221125_WJC_METTL3_EV_vs_WT_F01.15213.15213.2 0.000122 16-Aug R.LIVNVNDLR.R sp|P25205|MCM3_HUMAN 1 1054.6135 0.53 3687 15213 2 1054.611552 528.314 DNA replication licensing factor MCM3 OS=Homo sapiens OX=9606 GN=MCM3 PE=1 SV=3 5.84 3171.5 - 731763 - - - -1.8414 - 1.687 0.453 - 203.2 1 2 0 -0.0019 9 0 0 0 2.94E+07 5.50E+07 - - - 3.8992 0.9778 221125_WJC_METTL3_EV_vs_WT_F01.15217.15217.2 0.743 14-Jun K.AVIELLEK[136.11].S "sp|Q6UB35|C1TM_HUMAN,tr|A0A087WVM4|A0A087WVM4_HUMAN,tr|B7ZM99|B7ZM99_HUMAN,tr|H0Y327|H0Y327_HUMAN,tr|Q5JYA8|Q5JYA8_HUMAN,tr|Q5JYA3|Q5JYA3_HUMAN" 6 921.5626 6.41 3690 15217 2 921.560979 461.7886 "Monofunctional C1-tetrahydrofolate synthase, mitochondrial OS=Homo sapiens OX=9606 GN=MTHFD1L PE=1 SV=1" 4.53 3171.9 - 1.78E+06 - - - -1.7959 - 1.383 0.083 - 118.9 2 2 0 -0.0017 8 0 0 0 2.53E+08 3.95E+07 - - - 0.497 0.9874 221125_WJC_METTL3_EV_vs_WT_F01.15239.15239.2 0.266 14-Jun K.FVIPLHSA.- sp|Q96F86|EDC3_HUMAN 1 882.4963 - 3704 15239 2 882.495167 442.2554 Enhancer of mRNA-decapping protein 3 OS=Homo sapiens OX=9606 GN=EDC3 PE=1 SV=1 6.74 3174.7 - 749985 - - - -1.3281 - 1.191 0.152 - 107.3 1 2 0 -0.0012 8 0 0 0 - - - - - 0.6905 0.9994 221125_WJC_METTL3_EV_vs_WT_F01.15241.15241.2 0.002 22-Dec K.VLPPPAGYVPIR[166.11].T sp|O75533|SF3B1_HUMAN 1 1287.7579 1.3 3705 15241 2 1287.756506 644.8862 Splicing factor 3B subunit 1 OS=Homo sapiens OX=9606 GN=SF3B1 PE=1 SV=3 8.72 3174.9 - 1.16E+06 - - - -1.0538 - 1.777 0.335 - 280.2 1 2 0 -0.0014 12 0 0 0 5.79E+07 4.45E+07 - - - 3.0276 0.9998 221125_WJC_METTL3_EV_vs_WT_F01.15242.15242.2 6.78E-05 18-Aug K.LLANMVYQYK[136.11].G "sp|P28074|PSB5_HUMAN,tr|H0YJM8|H0YJM8_HUMAN" 2 1249.662 0.65 3706 15242 2 1249.661141 625.8383 Proteasome subunit beta type-5 OS=Homo sapiens OX=9606 GN=PSMB5 PE=1 SV=3 8.5 3175 - 666433 - - - -0.7114 - 1.866 0.482 - 202.7 1 2 0 -0.0009 10 0 0 0 2.71E+07 4.15E+07 - - - 4.342 0.9845 221125_WJC_METTL3_EV_vs_WT_F01.15243.15243.2 0.309 16-Jul R.FLPSPVVIK.K "sp|Q13618|CUL3_HUMAN,tr|H7C399|H7C399_HUMAN,tr|A0A087WTG3|A0A087WTG3_HUMAN" 3 998.6165 1.88 3707 15243 2 998.614629 500.3155 Cullin-3 OS=Homo sapiens OX=9606 GN=CUL3 PE=1 SV=2 8.75 3175.1 - 3.66E+06 - - - -1.8275 - 1.126 0.186 - 139.2 1 2 0 -0.0018 9 0 0 0 9.79E+07 5.20E+07 - - - 0.7575 0.9888 221125_WJC_METTL3_EV_vs_WT_F01.15244.15244.2 2.15 16-Aug R.SLQGTLVSK[136.11].L sp|Q15648|MED1_HUMAN 1 939.548 0.89 3708 15244 2 939.548857 470.7813 Mediator of RNA polymerase II transcription subunit 1 OS=Homo sapiens OX=9606 GN=MED1 PE=1 SV=4 8.47 3175.2 - 1.11E+06 - - - 0.8632 - 1.349 0.106 - 202.3 1 2 0 0.0008 9 0 0 0 2.87E+07 3.21E+07 - - - 0.6897 0.9993 221125_WJC_METTL3_EV_vs_WT_F01.15246.15246.2 0.000427 22-Oct K.NYIQGINLVQAK.K "sp|P52815|RM12_HUMAN,tr|B4DLN1|B4DLN1_HUMAN" 2 1359.7511 6.67 3710 15246 2 1359.748821 680.8828 "39S ribosomal protein L12, mitochondrial OS=Homo sapiens OX=9606 GN=MRPL12 PE=1 SV=2" 8.59 3175.5 - 323981 - - - -1.6393 - 1.645 0.389 - 170.4 1 2 0 -0.0022 12 0 0 0 4.60E+06 6.90E+05 - - - 3.2231 0.9991 221125_WJC_METTL3_EV_vs_WT_F01.15251.15251.2 0.0862 18-Jul R.LIYTAGGYFR.Q sp|Q14145|KEAP1_HUMAN 1 1159.6026 1.41 3712 15251 2 1159.600861 580.8086 Kelch-like ECH-associated protein 1 OS=Homo sapiens OX=9606 GN=KEAP1 PE=1 SV=2 8.59 3176.1 - 342522 - - - -1.4953 - 1.458 0.376 - 131 1 2 0 -0.0017 10 0 0 0 8.81E+06 6.26E+06 - - - 2.8701 0.9969 221125_WJC_METTL3_EV_vs_WT_F01.15253.15253.2 0.00497 12-Aug R.LLMLYTR[166.11].K "sp|Q8N1F7|NUP93_HUMAN,tr|H3BVG0|H3BVG0_HUMAN" 2 918.5236 1.21 3713 15253 2 918.52117 460.2691 Nuclear pore complex protein Nup93 OS=Homo sapiens OX=9606 GN=NUP93 PE=1 SV=2 8.75 3176.3 - 841969 - - - -2.6782 - 1.533 0.283 - 209.6 1 2 0 -0.0025 7 0 0 0 3.73E+07 3.07E+07 - - - 2.4842 0.8535 221125_WJC_METTL3_EV_vs_WT_F01.15256.15256.2 0.00852 14-Sep E.KDEPLSVK.H "sp|Q6P1J6|PLB1_HUMAN,tr|H7C012|H7C012_HUMAN,tr|H7BYX7|H7BYX7_HUMAN" 3 914.5073 1.55 3716 15256 2 914.509357 458.2609 "Phospholipase B1, membrane-associated OS=Homo sapiens OX=9606 GN=PLB1 PE=1 SV=3" 6.07 3176.7 - 948459 - - - 2.2526 - 1.526 0.273 - 229 1 1 0 0.0021 8 0 0 0 2.44E+07 1.57E+07 - - - 2.3314 0.9991 221125_WJC_METTL3_EV_vs_WT_F01.15260.15260.2 0.00213 20-Aug K.WEGLVYAPPGK[136.11].E "sp|Q9Y2W1|TR150_HUMAN,tr|A0A3B3ITZ9|A0A3B3ITZ9_HUMAN" 2 1223.643 2.08 3717 15260 2 1223.643902 612.8288 Thyroid hormone receptor-associated protein 3 OS=Homo sapiens OX=9606 GN=THRAP3 PE=1 SV=2 6 3177.3 - 420046 - - - 0.7298 - 1.429 0.35 - 151.2 1 2 0 0.0009 11 0 0 0 3.32E+07 1.60E+07 - - - 2.5915 0.9991 221125_WJC_METTL3_EV_vs_WT_F01.15270.15270.2 0.288 18-Sep K.ATLLLESGIR.L "sp|O60524|NEMF_HUMAN,tr|G3V547|G3V547_HUMAN,tr|G3V5V3|G3V5V3_HUMAN,tr|G3V4D9|G3V4D9_HUMAN" 4 1071.6288 0.89 3723 15270 2 1071.628713 536.8217 Nuclear export mediator factor NEMF OS=Homo sapiens OX=9606 GN=NEMF PE=1 SV=4 6.05 3178.5 - 607033 - - - -0.0896 - 1.843 0.23 - 222.9 1 2 0 -0.0001 10 0 0 0 1.12E+07 1.26E+07 - - - 2.4463 0.9685 221125_WJC_METTL3_EV_vs_WT_F01.15280.15280.2 5 14-Jun K.LVWIPSER[166.11].H "sp|P35580|MYH10_HUMAN,tr|E7ERA5|E7ERA5_HUMAN" 2 1008.5632 0.74 3729 15280 2 1008.563097 505.2889 Myosin-10 OS=Homo sapiens OX=9606 GN=MYH10 PE=1 SV=3 6 3179.8 - 1.46E+06 - - - -0.0882 - 1.174 0.045 - 148.1 1 2 0 -0.0001 8 0 0 0 3.67E+07 4.94E+07 - - - -0.1428 0.9845 221125_WJC_METTL3_EV_vs_WT_F01.15286.15286.2 0.419 12-Jul R.LLLAFQK[136.11].K sp|Q14781|CBX2_HUMAN 1 839.536 1.18 3732 15286 2 839.535567 420.7753 Chromobox protein homolog 2 OS=Homo sapiens OX=9606 GN=CBX2 PE=1 SV=2 8.75 3180.5 - 1.12E+06 - - - -0.5455 - 1.436 0.022 - 116.1 1 2 0 -0.0005 7 0 0 0 2.79E+07 2.36E+07 - - - 0.3499 0.9952 221125_WJC_METTL3_EV_vs_WT_F01.15287.15287.2 0.00326 20-Aug K.VLVEGPLNNLR[166.11].E sp|Q92900|RENT1_HUMAN 1 1232.7116 0.49 3733 15287 2 1232.714586 617.3631 Regulator of nonsense transcripts 1 OS=Homo sapiens OX=9606 GN=UPF1 PE=1 SV=2 5.97 3180.6 - 266142 - - - 2.389 - 1.464 0.257 - 111.3 1 2 0 0.0029 11 0 0 0 4.74E+06 9.61E+06 - - - 1.9694 0.9693 221125_WJC_METTL3_EV_vs_WT_F01.15289.15289.2 1.81 18-Jun K.VMEALSLYTK[136.11].L sp|Q92783|STAM1_HUMAN 1 1161.6195 2.48 3735 15289 2 1161.617118 581.817 Signal transducing adapter molecule 1 OS=Homo sapiens OX=9606 GN=STAM PE=1 SV=3 5.97 3180.9 - 226807 - - - -2.048 - 1.25 0.099 - 68.4 1 2 0 -0.0024 10 0 0 0 6.65E+06 2.68E+06 - - - 0.3943 0.9996 221125_WJC_METTL3_EV_vs_WT_F01.15297.15297.2 0.0312 18-Jul K.VMEALSLYTK.L sp|Q92783|STAM1_HUMAN 1 1153.6053 2.27 3741 15297 2 1153.6062 577.8099 Signal transducing adapter molecule 1 OS=Homo sapiens OX=9606 GN=STAM PE=1 SV=3 5.97 3181.9 - 273089 - - - 0.7828 - 1.893 0.349 - 132 1 2 0 0.0009 10 0 0 0 6.65E+06 2.93E+06 - - - 3.3997 0.9599 221125_WJC_METTL3_EV_vs_WT_F01.15305.15305.2 0.0479 14-Aug N.IIEEALIR[166.11].R "sp|Q96EQ8|RN125_HUMAN,sp|P78527|PRKDC_HUMAN" 2 965.5785 43.33 3747 15305 2 965.578006 483.7965 E3 ubiquitin-protein ligase RNF125 OS=Homo sapiens OX=9606 GN=RNF125 PE=1 SV=4 4.53 3182.7 - 1.80E+06 - - - -0.5137 - 1.788 0.262 - 200.4 1 1 0 -0.0005 8 0 0 0 2.28E+09 5.26E+07 - - - 2.7285 0.9982 221125_WJC_METTL3_EV_vs_WT_F01.15313.15313.2 0.0101 18-Aug R.GLIENPALLR.W sp|O95168|NDUB4_HUMAN 1 1094.6448 1.35 3753 15313 2 1094.646891 548.3297 NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 4 OS=Homo sapiens OX=9606 GN=NDUFB4 PE=1 SV=3 6 3183.6 - 497208 - - - 1.9157 - 1.933 0.223 - 122.6 1 2 0 0.0021 10 0 0 0 3.47E+07 2.58E+07 - - - 2.5271 0.9546 221125_WJC_METTL3_EV_vs_WT_F01.15314.15314.2 0.385 16-May K.LIPPQDILR[166.11].D sp|Q96A65|EXOC4_HUMAN 1 1073.6472 0.79 3754 15314 2 1073.648682 537.8309 Exocyst complex component 4 OS=Homo sapiens OX=9606 GN=EXOC4 PE=1 SV=1 5.84 3183.8 - 218933 - - - 1.3338 - 1.103 0.097 - 67.8 2 2 0 0.0014 9 0 0 0 1.40E+07 1.78E+07 - - - -0.0939 0.9996 221125_WJC_METTL3_EV_vs_WT_F01.15315.15315.2 0.00127 20-Sep R.LFSGDVVLTAR.D "sp|P16152|CBR1_HUMAN,tr|E9PQ63|E9PQ63_HUMAN,tr|A8MTM1|A8MTM1_HUMAN" 3 1176.6503 1.07 3755 15315 2 1176.649067 589.3324 Carbonyl reductase [NADPH] 1 OS=Homo sapiens OX=9606 GN=CBR1 PE=1 SV=3 5.84 3183.9 - 187990 - - - -1.0249 - 1.906 0.349 - 232.4 1 2 0 -0.0012 11 0 0 0 8.92E+07 8.34E+07 - - - 3.3632 0.9999 221125_WJC_METTL3_EV_vs_WT_F01.15319.15319.3 6.15E-05 Sep-36 R.ILIAK[136.11]PIMFR[166.11].G "sp|Q9UN86|G3BP2_HUMAN,tr|A0A7I2V647|A0A7I2V647_HUMAN,tr|A0A7I2YQD9|A0A7I2YQD9_HUMAN,tr|A0A7I2V3P9|A0A7I2V3P9_HUMAN" 4 1218.7641 1.27 3757 15319 3 1218.765401 407.262 Ras GTPase-activating protein-binding protein 2 OS=Homo sapiens OX=9606 GN=G3BP2 PE=1 SV=2 11 3184.4 - 1.53E+06 - - - 1.0338 - 2.033 0.432 - 76.6 1 2 0 0.0013 10 0 0 0 2.74E+08 2.15E+08 - - - 5.4281 0.9998 221125_WJC_METTL3_EV_vs_WT_F01.15320.15320.2 0.00121 18-Nov R.GLIENPALLR[166.11].W sp|O95168|NDUB4_HUMAN 1 1104.6531 1.35 3758 15320 2 1104.653371 553.3338 NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 4 OS=Homo sapiens OX=9606 GN=NDUFB4 PE=1 SV=3 6 3184.6 - 727387 - - - 0.2779 - 2.348 0.382 - 344.2 1 2 0 0.0003 10 0 0 0 3.47E+07 2.58E+07 - - - 4.2449 0.9999 221125_WJC_METTL3_EV_vs_WT_F01.15321.15321.3 0.000212 Nov-36 R.ILIAKPIMFR.G "sp|Q9UN86|G3BP2_HUMAN,tr|A0A7I2V647|A0A7I2V647_HUMAN,tr|A0A7I2YQD9|A0A7I2YQD9_HUMAN,tr|A0A7I2V3P9|A0A7I2V3P9_HUMAN" 4 1200.7417 1.27 3759 15321 3 1200.74421 401.2545 Ras GTPase-activating protein-binding protein 2 OS=Homo sapiens OX=9606 GN=G3BP2 PE=1 SV=2 11 3184.6 - 1.22E+06 - - - 2.1145 - 2.194 0.471 - 137.9 1 2 0 0.0025 10 0 0 0 2.74E+08 2.15E+08 - - - 6.0851 0.9994 221125_WJC_METTL3_EV_vs_WT_F01.15322.15322.2 0.00566 20-Nov K.ALILVGGYGTR.L "sp|Q9Y5P6|GMPPB_HUMAN,tr|A0A7I2V691|A0A7I2V691_HUMAN,tr|A0A7I2V2Y5|A0A7I2V2Y5_HUMAN,tr|A0A7I2YQI5|A0A7I2YQI5_HUMAN,tr|A0A7I2V4B5|A0A7I2V4B5_HUMAN" 5 1118.6448 1.02 3760 15322 2 1118.646173 560.3297 Mannose-1-phosphate guanyltransferase beta OS=Homo sapiens OX=9606 GN=GMPPB PE=1 SV=2 8.79 3184.8 - 780223 - - - 1.2327 - 2.16 0.293 - 330.7 1 2 0 0.0014 11 0 0 0 2.47E+07 2.43E+07 - - - 3.288 0.9998 221125_WJC_METTL3_EV_vs_WT_F01.15333.15333.2 0.000352 20-Aug R.LFSGDVVLTAR[166.11].D "sp|P16152|CBR1_HUMAN,tr|E9PQ63|E9PQ63_HUMAN,tr|A8MTM1|A8MTM1_HUMAN" 3 1186.6585 1.06 3770 15333 2 1186.659096 594.3365 Carbonyl reductase [NADPH] 1 OS=Homo sapiens OX=9606 GN=CBR1 PE=1 SV=3 5.84 3186.2 - 886550 - - - 0.466 - 1.701 0.496 - 185.3 1 2 0 0.0006 11 0 0 0 9.06E+07 8.51E+07 - - - 4.1413 0.9999 221125_WJC_METTL3_EV_vs_WT_F01.15334.15334.2 0.000681 13/22 R.VLVTGATGLLGR[166.11].A "sp|Q9NZL9|MAT2B_HUMAN,tr|E5RJR3|E5RJR3_HUMAN" 2 1165.7058 0.85 3771 15334 2 1165.706508 583.8602 Methionine adenosyltransferase 2 subunit beta OS=Homo sapiens OX=9606 GN=MAT2B PE=1 SV=1 9.72 3186.3 - 595568 - - - 0.5833 - 2.607 0.51 - 507.9 1 2 0 0.0007 12 0 0 0 1.74E+07 2.06E+07 - - - 5.3288 0.9298 221125_WJC_METTL3_EV_vs_WT_F01.15335.15335.2 2.02 16-May K.IYPVGYFTK.E "sp|Q15517|CDSN_HUMAN,tr|G8JLG2|G8JLG2_HUMAN,tr|Q2L6G8|Q2L6G8_HUMAN" 3 1086.575 11.11 3772 15335 2 1086.576113 544.2948 Corneodesmosin OS=Homo sapiens OX=9606 GN=CDSN PE=1 SV=3 8.5 3186.4 - 357239 - - - 1.04 - 1.111 0.082 - 44.7 9 2 0 0.0011 9 0 0 0 5.18E+07 4.66E+06 - - - -0.4754 0.9998 221125_WJC_METTL3_EV_vs_WT_F01.15336.15336.2 0.00305 22-Nov R.VLVTGATGLLGR.A "sp|Q9NZL9|MAT2B_HUMAN,tr|E5RJR3|E5RJR3_HUMAN" 2 1155.6976 0.85 3773 15336 2 1155.698063 578.8561 Methionine adenosyltransferase 2 subunit beta OS=Homo sapiens OX=9606 GN=MAT2B PE=1 SV=1 9.72 3186.6 - 293736 - - - 0.437 - 2.167 0.432 - 409.7 1 2 0 0.0005 12 0 0 0 1.74E+07 2.06E+07 - - - 4.2664 0.9984 221125_WJC_METTL3_EV_vs_WT_F01.15342.15342.2 0.00081 14-Jul R.ELYPVEFR[166.11].N "sp|Q5BJF2|SGMR2_HUMAN,tr|J3KT68|J3KT68_HUMAN" 2 1061.5421 1.6 3777 15342 2 1061.538973 531.7783 Sigma intracellular receptor 2 OS=Homo sapiens OX=9606 GN=TMEM97 PE=1 SV=1 4.53 3187.3 - 637905 - - - -2.9608 - 1.484 0.42 - 199 1 2 0 -0.0031 8 0 0 0 2.62E+07 1.65E+07 - - - 3.3327 0.9994 221125_WJC_METTL3_EV_vs_WT_F01.15343.15343.2 0.00577 18-Aug R.ILIAKPIMFR.G "sp|Q9UN86|G3BP2_HUMAN,tr|A0A7I2V647|A0A7I2V647_HUMAN,tr|A0A7I2YQD9|A0A7I2YQD9_HUMAN,tr|A0A7I2V3P9|A0A7I2V3P9_HUMAN" 4 1200.7417 1.37 3778 15343 2 1200.741046 601.3781 Ras GTPase-activating protein-binding protein 2 OS=Homo sapiens OX=9606 GN=G3BP2 PE=1 SV=2 11 3187.4 - 513155 - - - -0.5205 - 1.705 0.324 - 265.9 1 2 0 -0.0006 10 0 0 0 2.60E+07 1.90E+07 - - - 2.9232 0.9775 221125_WJC_METTL3_EV_vs_WT_F01.15344.15344.2 0.0171 16-Aug L.LIAKPIMFR.G "sp|Q9UN86|G3BP2_HUMAN,tr|A0A7I2V647|A0A7I2V647_HUMAN,tr|A0A7I2YQD9|A0A7I2YQD9_HUMAN,tr|A0A7I2V3P9|A0A7I2V3P9_HUMAN" 4 1087.6576 2.65 3779 15344 2 1087.657236 544.8361 Ras GTPase-activating protein-binding protein 2 OS=Homo sapiens OX=9606 GN=G3BP2 PE=1 SV=2 11 3187.6 - 431625 - - - -0.3411 - 1.478 0.424 - 180.3 1 1 0 -0.0004 9 0 0 0 1.90E+07 7.17E+06 - - - 3.3028 0.9799 221125_WJC_METTL3_EV_vs_WT_F01.15355.15355.2 0.0196 18-Oct H.ILSPWGAEVK.A "sp|P09874|PARP1_HUMAN,tr|A0A7I2V3E1|A0A7I2V3E1_HUMAN" 2 1098.6073 1.07 3785 15355 2 1098.606799 550.3109 Poly [ADP-ribose] polymerase 1 OS=Homo sapiens OX=9606 GN=PARP1 PE=1 SV=4 6 3188.9 - 1.24E+06 - - - -0.4979 - 2.057 0.325 - 272.1 1 1 0 -0.0005 10 0 0 0 1.32E+08 1.23E+08 - - - 3.4545 0.9387 221125_WJC_METTL3_EV_vs_WT_F01.15359.15359.2 0.00176 18-Nov H.ILSPWGAEVK[136.11].A "sp|P09874|PARP1_HUMAN,tr|A0A7I2V3E1|A0A7I2V3E1_HUMAN" 2 1106.6215 1.11 3788 15359 2 1106.618468 554.318 Poly [ADP-ribose] polymerase 1 OS=Homo sapiens OX=9606 GN=PARP1 PE=1 SV=4 6 3189.3 - 1.70E+06 - - - -2.7814 - 1.893 0.381 - 282.9 1 1 0 -0.0031 10 0 0 0 1.32E+08 1.18E+08 - - - 3.6354 0.9698 221125_WJC_METTL3_EV_vs_WT_F01.15360.15360.2 0.00272 14-Jul L.IAKPIMFR.G "sp|Q9UN86|G3BP2_HUMAN,tr|A0A7I2V647|A0A7I2V647_HUMAN,tr|A0A7I2YQD9|A0A7I2YQD9_HUMAN,tr|A0A7I2V3P9|A0A7I2V3P9_HUMAN" 4 974.5735 1.65 3789 15360 2 974.572655 488.294 Ras GTPase-activating protein-binding protein 2 OS=Homo sapiens OX=9606 GN=G3BP2 PE=1 SV=2 11 3189.4 - 911286 - - - -0.9112 - 1.542 0.377 - 149.4 1 1 0 -0.0009 8 0 0 0 2.83E+07 1.72E+07 - - - 3.1314 0.9979 221125_WJC_METTL3_EV_vs_WT_F01.15363.15363.2 0.000102 14-Aug K.YFEYIMAK[136.11].E sp|P13674|P4HA1_HUMAN 1 1071.5191 1.54 3790 15363 2 1071.516269 536.7668 Prolyl 4-hydroxylase subunit alpha-1 OS=Homo sapiens OX=9606 GN=P4HA1 PE=1 SV=2 6 3189.8 - 593000 - - - -2.5991 - 1.451 0.356 - 173.8 1 2 0 -0.0028 8 0 0 0 1.60E+08 1.04E+08 - - - 2.7922 0.9977 221125_WJC_METTL3_EV_vs_WT_F01.15364.15364.2 0.0288 12-Jul K.YLDWAYR[166.11].S sp|Q9NYH9|UTP6_HUMAN 1 995.474 1.42 3791 15364 2 995.474571 498.7443 U3 small nucleolar RNA-associated protein 6 homolog OS=Homo sapiens OX=9606 GN=UTP6 PE=1 SV=2 5.83 3189.9 - 969291 - - - 0.5364 - 1.274 0.265 - 164.8 1 2 0 0.0005 7 0 0 0 2.72E+07 1.92E+07 - - - 1.7654 0.9743 221125_WJC_METTL3_EV_vs_WT_F01.15366.15366.2 0.017 14-Jul R.ELYPVEFR.N "sp|Q5BJF2|SGMR2_HUMAN,tr|J3KT68|J3KT68_HUMAN" 2 1051.5338 2.03 3793 15366 2 1051.528416 526.7742 Sigma intracellular receptor 2 OS=Homo sapiens OX=9606 GN=TMEM97 PE=1 SV=1 4.53 3190.1 - 956141 - - - -5.1639 - 1.329 0.312 - 209.9 1 2 0 -0.0054 8 0 0 0 4.08E+07 2.01E+07 - - - 2.2015 0.9689 221125_WJC_METTL3_EV_vs_WT_F01.15371.15371.2 0.057 16-Jul K.VLPVGVLYK.V "sp|Q03393|PTPS_HUMAN,tr|E9PNN3|E9PNN3_HUMAN" 2 986.6165 3.54 3796 15371 2 986.612746 494.3155 6-pyruvoyl tetrahydrobiopterin synthase OS=Homo sapiens OX=9606 GN=PTS PE=1 SV=1 8.56 3190.7 - 1.09E+06 - - - -3.7583 - 1.291 0.199 - 104.9 1 2 0 -0.0037 9 0 0 0 3.71E+08 1.05E+08 - - - 1.2486 0.9933 221125_WJC_METTL3_EV_vs_WT_F01.15372.15372.2 0.9 12-Jul K.AGFLDLK[136.11].D sp|Q9Y490|TLN1_HUMAN 1 770.4418 0.83 3797 15372 2 770.439885 386.2282 Talin-1 OS=Homo sapiens OX=9606 GN=TLN1 PE=1 SV=3 5.88 3190.8 - 1.24E+06 - - - -2.4726 - 1.396 0.219 - 147.7 1 2 0 -0.0019 7 0 0 0 2.59E+07 3.13E+07 - - - 1.715 0.9998 221125_WJC_METTL3_EV_vs_WT_F01.15386.15386.2 0.00352 14-Oct K.NLQLLMDR.V "sp|O15372|EIF3H_HUMAN,tr|B3KS98|B3KS98_HUMAN,tr|A0A087WZK9|A0A087WZK9_HUMAN,tr|E5RJT0|E5RJT0_HUMAN" 4 1001.5328 999 3803 15386 2 1001.532362 501.7737 Eukaryotic translation initiation factor 3 subunit H OS=Homo sapiens OX=9606 GN=EIF3H PE=1 SV=1 5.84 3192.6 - 6.93E+06 - - - -0.4383 - 1.994 0.372 - 475.1 1 2 0 -0.0004 8 0 0 0 2.32E+08 0.00E+00 - - - 3.8699 0.9587 221125_WJC_METTL3_EV_vs_WT_F01.15395.15395.2 1.69 16-Aug R.ILPQDVILK[136.11].F "sp|Q96GQ7|DDX27_HUMAN,tr|B7Z6D5|B7Z6D5_HUMAN" 2 1045.6627 1.17 3810 15395 2 1045.661605 523.8386 Probable ATP-dependent RNA helicase DDX27 OS=Homo sapiens OX=9606 GN=DDX27 PE=1 SV=2 5.84 3193.8 - 1.31E+06 - - - -1.03 - 0.926 0.134 - 112.8 1 2 0 -0.0011 9 0 0 0 3.31E+07 2.84E+07 - - - -0.192 0.9781 221125_WJC_METTL3_EV_vs_WT_F01.15401.15401.2 0.146 22-Sep K.VLPPPAGYVPIR.T sp|O75533|SF3B1_HUMAN 1 1277.7496 1.31 3814 15401 2 1277.743646 639.8821 Splicing factor 3B subunit 1 OS=Homo sapiens OX=9606 GN=SF3B1 PE=1 SV=3 8.72 3194.5 - 872792 - - - -4.6543 - 1.506 0.259 - 166.2 1 2 0 -0.0059 12 0 0 0 5.84E+07 4.46E+07 - - - 2.0295 0.9992 221125_WJC_METTL3_EV_vs_WT_F01.15405.15405.2 0.0121 14-Sep K.GIAYIEFK.T "sp|P19338|NUCL_HUMAN,tr|A0A7I2V506|A0A7I2V506_HUMAN,tr|A0A7I2V2U7|A0A7I2V2U7_HUMAN,tr|A0A7I2V3F3|A0A7I2V3F3_HUMAN,tr|A0A7I2V428|A0A7I2V428_HUMAN,tr|A0A7I2V349|A0A7I2V349_HUMAN,tr|H7BY16|H7BY16_HUMAN,tr|A0A7I2V5M5|A0A7I2V5M5_HUMAN,tr|C9JLB1|C9JLB1_HUMAN" 9 939.5066 1.16 3816 15405 2 939.505111 470.7606 Nucleolin OS=Homo sapiens OX=9606 GN=NCL PE=1 SV=3 6 3195 - 3.10E+06 - - - -1.5519 - 1.788 0.295 - 262.5 1 2 0 -0.0015 8 0 0 0 6.34E+08 5.48E+08 - - - 2.972 0.9985 221125_WJC_METTL3_EV_vs_WT_F01.15406.15406.2 0.000759 16-Sep K.VLPVGVLYK[136.11].V "sp|Q03393|PTPS_HUMAN,tr|E9PNN3|E9PNN3_HUMAN" 2 994.6307 3.53 3817 15406 2 994.6277 498.3226 6-pyruvoyl tetrahydrobiopterin synthase OS=Homo sapiens OX=9606 GN=PTS PE=1 SV=1 8.56 3195.1 - 1.51E+06 - - - -2.9699 - 1.675 0.396 - 197.6 1 2 0 -0.003 9 0 0 0 3.71E+08 1.05E+08 - - - 3.4572 0.9978 221125_WJC_METTL3_EV_vs_WT_F01.15407.15407.2 0.00312 20-Sep K.FSPAGPVLSIR.V "sp|Q13310|PABP4_HUMAN,tr|B1ANR0|B1ANR0_HUMAN,tr|A0A7I2V4L7|A0A7I2V4L7_HUMAN,tr|B1ANR1|B1ANR1_HUMAN" 4 1142.6448 1.35 3818 15407 2 1142.640594 572.3297 Polyadenylate-binding protein 4 OS=Homo sapiens OX=9606 GN=PABPC4 PE=1 SV=1 9.75 3195.2 - 671272 - - - -3.6757 - 1.678 0.427 - 208.8 1 2 0 -0.0042 11 0 0 0 4.63E+07 3.42E+07 - - - 3.5937 0.9962 221125_WJC_METTL3_EV_vs_WT_F01.15412.15412.2 1.75E-06 20-Oct K.FSPAGPVLSIR[166.11].V "sp|Q13310|PABP4_HUMAN,tr|B1ANR0|B1ANR0_HUMAN,tr|A0A7I2V4L7|A0A7I2V4L7_HUMAN,tr|B1ANR1|B1ANR1_HUMAN" 4 1152.6531 1.48 3820 15412 2 1152.646782 577.3338 Polyadenylate-binding protein 4 OS=Homo sapiens OX=9606 GN=PABPC4 PE=1 SV=1 9.75 3195.9 - 872927 - - - -5.45 - 1.725 0.55 - 358.2 1 2 0 -0.0063 11 0 0 0 4.62E+07 3.13E+07 - - - 4.5763 0.9922 221125_WJC_METTL3_EV_vs_WT_F01.15414.15414.2 0.116 14-Jul R.LLGWIQNK[136.11].L "sp|O75369|FLNB_HUMAN,sp|Q14315|FLNC_HUMAN,sp|P21333|FLNA_HUMAN,tr|A0A7P0NMY4|A0A7P0NMY4_HUMAN,tr|Q60FE5|Q60FE5_HUMAN,tr|A0A7I2V3E6|A0A7I2V3E6_HUMAN,tr|A0A804HK76|A0A804HK76_HUMAN,tr|A0A804HJC2|A0A804HJC2_HUMAN,tr|A0A087WWY3|A0A087WWY3_HUMAN,tr|A0A804HL72|A0A804HL72_HUMAN,tr|F8WE98|F8WE98_HUMAN" 11 978.5742 2.72 3822 15414 2 978.57359 490.2944 Filamin-B OS=Homo sapiens OX=9606 GN=FLNB PE=1 SV=2 8.75 3196.1 - 943474 - - - -0.6254 - 1.173 0.177 - 100.2 1 2 0 -0.0006 8 0 0 0 3.54E+07 1.30E+07 - - - 0.8294 0.9225 221125_WJC_METTL3_EV_vs_WT_F01.15417.15417.2 0.0113 20-Dec R.ILMVGLDAAGK.T "sp|P18085|ARF4_HUMAN,sp|P84077|ARF1_HUMAN,sp|P61204|ARF3_HUMAN,sp|P84085|ARF5_HUMAN,tr|F5H423|F5H423_HUMAN,tr|F5H1V1|F5H1V1_HUMAN,tr|C9J1Z8|C9J1Z8_HUMAN,tr|F5H6T5|F5H6T5_HUMAN,tr|C9JPM4|C9JPM4_HUMAN,tr|F8WDB3|F8WDB3_HUMAN,tr|F5H0C7|F5H0C7_HUMAN" 11 1086.6107 0.95 3823 15417 2 1086.620704 544.3126 ADP-ribosylation factor 4 OS=Homo sapiens OX=9606 GN=ARF4 PE=1 SV=3 5.84 3196.5 - 2.70E+06 - - - 9.191 - 1.66 0.32 - 288 1 2 0 0.01 11 0 0 0 3.48E+08 3.66E+08 - - - 2.7724 0.9908 221125_WJC_METTL3_EV_vs_WT_F01.15418.15418.2 0.0116 14-Aug K.AVWLPAVK[136.11].A "sp|P63010|AP2B1_HUMAN,tr|A0A087X253|A0A087X253_HUMAN" 2 890.5469 0.96 3824 15418 2 890.543684 446.2807 AP-2 complex subunit beta OS=Homo sapiens OX=9606 GN=AP2B1 PE=1 SV=1 8.8 3196.6 - 1.01E+06 - - - -3.6382 - 1.399 0.283 - 261.4 1 2 0 -0.0032 8 0 0 0 3.69E+07 3.85E+07 - - - 2.1429 0.9928 221125_WJC_METTL3_EV_vs_WT_F01.15419.15419.2 0.112 12-Aug R.LYDGLFK.V "sp|Q16531|DDB1_HUMAN,tr|F5GWI0|F5GWI0_HUMAN,tr|F5H2L3|F5H2L3_HUMAN,tr|A0A7P0TAK7|A0A7P0TAK7_HUMAN,tr|A0A7P0Z3Z5|A0A7P0Z3Z5_HUMAN,tr|F5GZY8|F5GZY8_HUMAN,tr|F5GY55|F5GY55_HUMAN,tr|A0A7P0Z4B9|A0A7P0Z4B9_HUMAN,tr|A0A7P0Z4L2|A0A7P0Z4L2_HUMAN,tr|A0A7P0T965|A0A7P0T965_HUMAN" 10 854.4538 1.12 3825 15419 2 854.450389 428.2342 DNA damage-binding protein 1 OS=Homo sapiens OX=9606 GN=DDB1 PE=1 SV=1 5.83 3196.7 - 3.93E+06 - - - -3.9979 - 1.355 0.351 - 177.9 1 2 0 -0.0034 7 0 0 0 1.71E+08 1.53E+08 - - - 2.595 0.9988 221125_WJC_METTL3_EV_vs_WT_F01.15423.15423.2 0.0125 14-Jul K.GIAYIEFK[136.11].T "sp|P19338|NUCL_HUMAN,tr|A0A7I2V506|A0A7I2V506_HUMAN,tr|A0A7I2V2U7|A0A7I2V2U7_HUMAN,tr|A0A7I2V3F3|A0A7I2V3F3_HUMAN,tr|A0A7I2V428|A0A7I2V428_HUMAN,tr|A0A7I2V349|A0A7I2V349_HUMAN,tr|H7BY16|H7BY16_HUMAN,tr|A0A7I2V5M5|A0A7I2V5M5_HUMAN,tr|C9JLB1|C9JLB1_HUMAN" 9 947.5208 1.16 3827 15423 2 947.519628 474.7677 Nucleolin OS=Homo sapiens OX=9606 GN=NCL PE=1 SV=3 6 3197.2 - 1.05E+07 - - - -1.2042 - 1.519 0.287 - 153.4 1 2 0 -0.0011 8 0 0 0 6.32E+08 5.44E+08 - - - 2.4212 0.9995 221125_WJC_METTL3_EV_vs_WT_F01.15424.15424.2 0.000109 20-Dec R.ILMVGLDAAGK[136.11].T "sp|P18085|ARF4_HUMAN,sp|P84077|ARF1_HUMAN,sp|P61204|ARF3_HUMAN,sp|P84085|ARF5_HUMAN,tr|F5H423|F5H423_HUMAN,tr|F5H1V1|F5H1V1_HUMAN,tr|C9J1Z8|C9J1Z8_HUMAN,tr|F5H6T5|F5H6T5_HUMAN,tr|C9JPM4|C9JPM4_HUMAN,tr|F8WDB3|F8WDB3_HUMAN,tr|F5H0C7|F5H0C7_HUMAN" 11 1094.6249 0.95 3828 15424 2 1094.622079 548.3197 ADP-ribosylation factor 4 OS=Homo sapiens OX=9606 GN=ARF4 PE=1 SV=3 5.84 3197.2 - 3.70E+06 - - - -2.5927 - 2.355 0.415 - 420.6 1 2 0 -0.0028 11 0 0 0 3.46E+08 3.66E+08 - - - 4.4224 0.8356 221125_WJC_METTL3_EV_vs_WT_F01.15434.15434.2 0.092 18-May D.VDEATGAVKK[136.11].H sp|Q96ST3|SIN3A_HUMAN 1 1024.5644 - 3835 15434 2 1024.566137 513.2895 Paired amphipathic helix protein Sin3a OS=Homo sapiens OX=9606 GN=SIN3A PE=1 SV=2 6.04 3198.5 - 1.14E+07 - - - 1.671 - 1.322 0.283 - 50.1 1 1 0 0.0017 10 0 0 0 - - - - - 1.9099 0.9968 221125_WJC_METTL3_EV_vs_WT_F01.15436.15436.2 0.0951 16-Sep R.LLLPGELAK[136.11].H "sp|Q8N257|H2B3B_HUMAN,sp|A0A2R8Y619|H2BE1_HUMAN,sp|P33778|H2B1B_HUMAN,sp|Q96A08|H2B1A_HUMAN,sp|Q5QNW6|H2B2F_HUMAN,sp|P58876|H2B1D_HUMAN,sp|Q99880|H2B1L_HUMAN,sp|P62807|H2B1C_HUMAN,sp|Q99877|H2B1N_HUMAN,sp|P57053|H2BFS_HUMAN,sp|P23527|H2B1O_HUMAN,sp|O60814|H2B1K_HUMAN,sp|Q93079|H2B1H_HUMAN,sp|Q99879|H2B1M_HUMAN,sp|Q16778|H2B2E_HUMAN,sp|P06899|H2B1J_HUMAN,tr|U3KQK0|U3KQK0_HUMAN" 17 960.6099 1.04 3836 15436 2 960.607529 481.3122 Histone H2B type 3-B OS=Homo sapiens OX=9606 GN=H2BU1 PE=1 SV=3 6 3198.7 - 2.62E+08 - - - -2.487 - 1.522 0.282 - 259.6 1 2 0 -0.0024 9 0 0 0 1.12E+10 1.07E+10 - - - 2.3383 0.9997 221125_WJC_METTL3_EV_vs_WT_F01.15438.15438.2 0.000296 18-Nov K.IGDLGLATLK.R "sp|Q9H4A3|WNK1_HUMAN,sp|Q96J92|WNK4_HUMAN,sp|Q9Y3S1|WNK2_HUMAN,tr|F5GWT4|F5GWT4_HUMAN,tr|A6PVV2|A6PVV2_HUMAN,tr|K7ENT7|K7ENT7_HUMAN,tr|F8W9F9|F8W9F9_HUMAN,tr|H0Y7T5|H0Y7T5_HUMAN,tr|F6UYG0|F6UYG0_HUMAN" 9 999.5964 1.47 3838 15438 2 999.594571 500.8055 Serine\threonine-protein kinase WNK1 OS=Homo sapiens OX=9606 GN=WNK1 PE=1 SV=2 5.84 3198.9 - 4.13E+06 - - - -1.8768 - 2.242 0.417 - 270.9 1 2 0 -0.0019 10 0 0 0 1.46E+08 9.88E+07 - - - 4.374 0.9998 221125_WJC_METTL3_EV_vs_WT_F01.15439.15439.2 0.00205 16-Oct R.MNVLADALK.S "sp|P62244|RS15A_HUMAN,tr|I3L246|I3L246_HUMAN,tr|I3L3P7|I3L3P7_HUMAN,tr|I3L303|I3L303_HUMAN,tr|H3BT37|H3BT37_HUMAN,tr|H3BV27|H3BV27_HUMAN,tr|H3BN98|H3BN98_HUMAN" 7 973.5267 0.83 3839 15439 2 973.525883 487.7706 40S ribosomal protein S15a OS=Homo sapiens OX=9606 GN=RPS15A PE=1 SV=2 5.59 3199 - 560310 - - - -0.7909 - 2.13 0.435 - 318.4 1 2 0 -0.0008 9 0 0 0 3.42E+08 4.14E+08 - - - 4.4412 0.9976 221125_WJC_METTL3_EV_vs_WT_F01.15441.15441.2 0.175 16-Sep R.LLLPGELAK.H "sp|Q8N257|H2B3B_HUMAN,sp|A0A2R8Y619|H2BE1_HUMAN,sp|P33778|H2B1B_HUMAN,sp|Q96A08|H2B1A_HUMAN,sp|Q5QNW6|H2B2F_HUMAN,sp|P58876|H2B1D_HUMAN,sp|Q99880|H2B1L_HUMAN,sp|P62807|H2B1C_HUMAN,sp|Q99877|H2B1N_HUMAN,sp|P57053|H2BFS_HUMAN,sp|P23527|H2B1O_HUMAN,sp|O60814|H2B1K_HUMAN,sp|Q93079|H2B1H_HUMAN,sp|Q99879|H2B1M_HUMAN,sp|Q16778|H2B2E_HUMAN,sp|P06899|H2B1J_HUMAN,tr|U3KQK0|U3KQK0_HUMAN" 17 952.5957 1.04 3840 15441 2 952.594928 477.3051 Histone H2B type 3-B OS=Homo sapiens OX=9606 GN=H2BU1 PE=1 SV=3 6 3199.2 - 2.79E+08 - - - -0.8293 - 1.564 0.19 - 269.9 1 2 0 -0.0008 9 0 0 0 1.12E+10 1.07E+10 - - - 1.738 0.9949 221125_WJC_METTL3_EV_vs_WT_F01.15443.15443.2 0.0184 12-Aug K.YGAFLLR[166.11].R "sp|Q14690|RRP5_HUMAN,tr|A0A3B3IUD7|A0A3B3IUD7_HUMAN" 2 848.4784 0.88 3841 15443 2 848.475131 425.2465 Protein RRP5 homolog OS=Homo sapiens OX=9606 GN=PDCD11 PE=1 SV=3 8.75 3199.4 - 843572 - - - -3.8457 - 1.792 0.26 - 216.8 1 2 0 -0.0033 7 0 0 0 1.00E+07 1.14E+07 - - - 2.8087 0.9668 221125_WJC_METTL3_EV_vs_WT_F01.15444.15444.2 5.47E-05 18-Aug Q.LLLSDC[160.03]PPDR[166.11].L sp|Q9H611|PIF1_HUMAN 1 1194.5942 0.04 3842 15444 2 1194.591538 598.3044 ATP-dependent DNA helicase PIF1 OS=Homo sapiens OX=9606 GN=PIF1 PE=1 SV=2 4.21 3199.6 - 302368 - - - -2.2526 - 1.546 0.5 - 145.2 1 1 0 -0.0027 10 0 0 0 2.13E+05 5.61E+06 - - - 3.9492 0.9995 221125_WJC_METTL3_EV_vs_WT_F01.15445.15445.2 5.48E-05 16-Oct R.MNVLADALK[136.11].S "sp|P62244|RS15A_HUMAN,tr|I3L246|I3L246_HUMAN,tr|I3L3P7|I3L3P7_HUMAN,tr|I3L303|I3L303_HUMAN,tr|H3BT37|H3BT37_HUMAN,tr|H3BV27|H3BV27_HUMAN,tr|H3BN98|H3BN98_HUMAN" 7 981.5409 0.83 3843 15445 2 981.538692 491.7777 40S ribosomal protein S15a OS=Homo sapiens OX=9606 GN=RPS15A PE=1 SV=2 5.59 3199.7 - 1.40E+06 - - - -2.2016 - 2.101 0.388 - 418 1 2 0 -0.0022 9 0 0 0 3.42E+08 4.14E+08 - - - 4.0539 0.8077 221125_WJC_METTL3_EV_vs_WT_F01.15446.15446.2 0.00163 12-Aug L.PVGVLYK.V "sp|Q03393|PTPS_HUMAN,tr|E9PNN3|E9PNN3_HUMAN" 2 774.464 2.08 3844 15446 2 774.461274 388.2393 6-pyruvoyl tetrahydrobiopterin synthase OS=Homo sapiens OX=9606 GN=PTS PE=1 SV=1 9.01 3199.8 - 732856 - - - -3.4889 - 1.662 0.293 - 191.7 1 1 0 -0.0027 7 0 0 0 7.00E+07 3.37E+07 - - - 2.8139 0.9751 221125_WJC_METTL3_EV_vs_WT_F01.15453.15453.2 5.92 14-Jul R.TLINELVK.G "sp|Q14204|DYHC1_HUMAN,tr|A0A7P0T9C4|A0A7P0T9C4_HUMAN,tr|A0A2R8Y706|A0A2R8Y706_HUMAN,tr|A0A7P0TAW9|A0A7P0TAW9_HUMAN,tr|A0A7P0TA13|A0A7P0TA13_HUMAN,tr|A0A7P0T9R4|A0A7P0T9R4_HUMAN,tr|A0A2R8Y5T0|A0A2R8Y5T0_HUMAN" 7 928.5593 0.8 3848 15453 2 928.558044 465.2869 Cytoplasmic dynein 1 heavy chain 1 OS=Homo sapiens OX=9606 GN=DYNC1H1 PE=1 SV=5 5.66 3200.7 - 889255 - - - -1.3882 - 1.177 0.098 - 113.1 1 2 0 -0.0013 8 0 0 0 1.84E+07 2.31E+07 - - - 0.2559 0.9996 221125_WJC_METTL3_EV_vs_WT_F01.15461.15461.2 0.0582 16-Sep R.LLLQLEATK[136.11].N "sp|Q13561|DCTN2_HUMAN,tr|H0YI98|H0YI98_HUMAN,tr|A8K8J9|A8K8J9_HUMAN,tr|F8W1I6|F8W1I6_HUMAN,tr|A0A7I2V4H4|A0A7I2V4H4_HUMAN,tr|A0A7I2V390|A0A7I2V390_HUMAN,tr|A0A7I2V4Y9|A0A7I2V4Y9_HUMAN,tr|F8VW18|F8VW18_HUMAN" 8 1035.6419 2.98 3853 15461 2 1035.640757 518.8282 Dynactin subunit 2 OS=Homo sapiens OX=9606 GN=DCTN2 PE=1 SV=4 6 3201.6 - 1.44E+06 - - - -1.149 - 1.785 0.364 - 204.1 1 2 0 -0.0012 9 0 0 0 2.01E+08 6.75E+07 - - - 3.4054 0.9974 221125_WJC_METTL3_EV_vs_WT_F01.15462.15462.2 0.142 18-Oct R.LAWGQPVGLR[166.11].H "sp|P47897|SYQ_HUMAN,tr|B4DDN1|B4DDN1_HUMAN,tr|H7C0R3|H7C0R3_HUMAN,tr|A0A0U1RQX5|A0A0U1RQX5_HUMAN,tr|A0A1B0GVU9|A0A1B0GVU9_HUMAN,tr|A0A0U1RQX9|A0A0U1RQX9_HUMAN,tr|A0A0U1RRC8|A0A0U1RRC8_HUMAN" 7 1105.6272 5.73 3854 15462 2 1105.62531 553.8209 Glutamine--tRNA ligase OS=Homo sapiens OX=9606 GN=QARS1 PE=1 SV=1 9.75 3201.7 - 621964 - - - -1.6941 - 1.555 0.239 - 303.5 1 2 0 -0.0019 10 0 0 0 2.57E+08 4.49E+07 - - - 2.038 0.9608 221125_WJC_METTL3_EV_vs_WT_F01.15463.15463.2 0.227 16-Jun K.VDLEQHLAR.L "sp|Q9BSA4|TTYH2_HUMAN,tr|B4DKD1|B4DKD1_HUMAN" 2 1079.5724 3.35 3855 15463 2 1079.573315 540.7935 Protein tweety homolog 2 OS=Homo sapiens OX=9606 GN=TTYH2 PE=1 SV=3 5.32 3201.8 - 596708 - - - 0.8874 - 1.31 0.024 - 81.7 2 2 0 0.001 9 0 0 0 2.24E+07 6.69E+06 - - - -0.1353 0.9957 221125_WJC_METTL3_EV_vs_WT_F01.15467.15467.2 1.55 12-Jul K.ILIEDWK[136.11].K "sp|P14314|GLU2B_HUMAN,tr|K7ELL7|K7ELL7_HUMAN,tr|A0A7I2V2T6|A0A7I2V2T6_HUMAN,tr|K7EPW7|K7EPW7_HUMAN" 4 923.5208 5.05 3858 15467 2 923.519665 462.7677 Glucosidase 2 subunit beta OS=Homo sapiens OX=9606 GN=PRKCSH PE=1 SV=2 4.37 3202.3 - 1.37E+06 - - - -1.1954 - 1.426 0.168 - 142.2 1 2 0 -0.0011 7 0 0 0 2.30E+08 4.56E+07 - - - 1.4059 0.9939 221125_WJC_METTL3_EV_vs_WT_F01.15469.15469.2 0.112 14-Jul K.AVWLPAVK.A "sp|P63010|AP2B1_HUMAN,tr|A0A087X253|A0A087X253_HUMAN" 2 882.5327 0.96 3859 15469 2 882.532596 442.2736 AP-2 complex subunit beta OS=Homo sapiens OX=9606 GN=AP2B1 PE=1 SV=1 8.8 3202.5 - 1.08E+06 - - - -0.145 - 1.328 0.143 - 185.5 1 2 0 -0.0001 8 0 0 0 3.69E+07 3.85E+07 - - - 0.9527 0.9965 221125_WJC_METTL3_EV_vs_WT_F01.15470.15470.2 0.008 16-Sep R.VFNPYTEFK.E sp|Q96C19|EFHD2_HUMAN 1 1143.5601 1.02 3860 15470 2 1143.556806 572.7873 EF-hand domain-containing protein D2 OS=Homo sapiens OX=9606 GN=EFHD2 PE=1 SV=1 5.97 3202.6 - 1.23E+06 - - - -2.8464 - 1.558 0.292 - 204.4 1 2 0 -0.0033 9 0 0 0 2.65E+07 2.60E+07 - - - 2.4795 0.9659 221125_WJC_METTL3_EV_vs_WT_F01.15471.15471.2 1.8 12-Jul R.LILQIGR[166.11].G "sp|Q9NP73|ALG13_HUMAN,tr|A0A096LNJ4|A0A096LNJ4_HUMAN,tr|A0A087WX43|A0A087WX43_HUMAN,tr|A0A087WTT9|A0A087WTT9_HUMAN,tr|D6RE84|D6RE84_HUMAN,tr|A0A096LP10|A0A096LP10_HUMAN,tr|A0A096LNL2|A0A096LNL2_HUMAN,tr|A0A1B0GVW6|A0A1B0GVW6_HUMAN" 8 821.5362 0.96 3861 15471 2 821.534939 411.7754 Putative bifunctional UDP-N-acetylglucosamine transferase and deubiquitinase ALG13 OS=Homo sapiens OX=9606 GN=ALG13 PE=1 SV=2 9.75 3202.7 - 2.62E+06 - - - -1.5873 - 1.553 0 - 169.2 5 2 0 -0.0013 7 0 0 0 1.55E+08 1.61E+08 - - - 0.1231 0.9971 221125_WJC_METTL3_EV_vs_WT_F01.15472.15472.2 0.486 12-Sep K.IIAALFK[136.11].A "sp|Q9Y4A5|TRRAP_HUMAN,tr|H0Y4W2|H0Y4W2_HUMAN,tr|F2Z2U4|F2Z2U4_HUMAN" 3 782.5146 1.58 3862 15472 2 782.513391 392.2646 Transformation\transcription domain-associated protein OS=Homo sapiens OX=9606 GN=TRRAP PE=1 SV=3 8.75 3202.8 - 642452 - - - -1.4952 - 1.757 0.139 - 202 1 2 0 -0.0012 7 0 0 0 2.39E+07 1.52E+07 - - - 1.8531 0.7624 221125_WJC_METTL3_EV_vs_WT_F01.15476.15476.2 11.4 12-Jul S.LIQLLGR.N "sp|Q9P035|HACD3_HUMAN,sp|P82930|RT34_HUMAN,tr|H3BPZ1|H3BPZ1_HUMAN,tr|H3BS72|H3BS72_HUMAN,tr|C9JJ19|C9JJ19_HUMAN,tr|H3BMZ1|H3BMZ1_HUMAN,tr|H3BRL8|H3BRL8_HUMAN" 7 811.528 0.96 3864 15476 2 811.526812 406.7713 Very-long-chain (3R)-3-hydroxyacyl-CoA dehydratase 3 OS=Homo sapiens OX=9606 GN=HACD3 PE=1 SV=2 9.75 3203.3 - 2.55E+06 - - - -1.4306 - 1.453 0.155 - 151.9 1 1 0 -0.0012 7 0 0 0 1.55E+08 1.61E+08 - - - 1.3693 0.9975 221125_WJC_METTL3_EV_vs_WT_F01.15477.15477.2 0.0474 14-Sep R.TAYLLYYR[166.11].R sp|Q14694|UBP10_HUMAN 1 1071.5629 0.95 3865 15477 2 1071.561849 536.7887 Ubiquitin carboxyl-terminal hydrolase 10 OS=Homo sapiens OX=9606 GN=USP10 PE=1 SV=2 8.16 3203.4 - 765807 - - - -0.936 - 1.228 0.281 - 263.1 1 2 0 -0.001 8 0 0 0 2.46E+07 2.60E+07 - - - 1.7356 0.9996 221125_WJC_METTL3_EV_vs_WT_F01.15485.15485.2 0.00218 14-Sep R.VLSIWEER.S "sp|Q96P16|RPR1A_HUMAN,tr|A0A0C4DGQ6|A0A0C4DGQ6_HUMAN" 2 1030.5447 0.53 3871 15485 2 1030.543449 516.2796 Regulation of nuclear pre-mRNA domain-containing protein 1A OS=Homo sapiens OX=9606 GN=RPRD1A PE=1 SV=1 4.53 3204.3 - 2.58E+06 - - - -1.2576 - 1.822 0.386 - 217.3 1 2 0 -0.0013 8 0 0 0 9.93E+07 1.86E+08 - - - 3.701 0.9917 221125_WJC_METTL3_EV_vs_WT_F01.15490.15490.2 0.000286 24-Oct K.LGPGAGAGFGVLR[166.11].R "sp|Q9BUL5|PHF23_HUMAN,tr|I3L1N0|I3L1N0_HUMAN,tr|I3L410|I3L410_HUMAN,tr|I3L4Q4|I3L4Q4_HUMAN" 4 1180.6592 1.7 3876 15490 2 1180.664723 591.3369 PHD finger protein 23 OS=Homo sapiens OX=9606 GN=PHF23 PE=1 SV=1 9.75 3205 - 220993 - - - 4.6677 - 1.929 0.302 - 248.3 1 2 0 0.0055 13 0 0 0 2.71E+07 1.60E+07 - - - 2.9561 0.997 221125_WJC_METTL3_EV_vs_WT_F01.15492.15492.2 0.0112 22-Jul K.VLPPPAGYVPIR[166.11].T sp|O75533|SF3B1_HUMAN 1 1287.7579 1.31 3877 15492 2 1287.759 644.8862 Splicing factor 3B subunit 1 OS=Homo sapiens OX=9606 GN=SF3B1 PE=1 SV=3 8.72 3205.2 - 310124 - - - 0.8829 - 1.616 0.183 - 65.3 1 2 0 0.0011 12 0 0 0 5.84E+07 4.46E+07 - - - 1.6551 0.998 221125_WJC_METTL3_EV_vs_WT_F01.15495.15495.2 0.0226 12-Jul K.MIFVGIK.K "sp|P99999|CYC_HUMAN,tr|C9JFR7|C9JFR7_HUMAN" 2 806.4724 1.26 3879 15495 2 806.472042 404.2435 Cytochrome c OS=Homo sapiens OX=9606 GN=CYCS PE=1 SV=2 8.5 3205.6 - 1.67E+06 - - - -0.4836 - 1.321 0.258 - 198.9 1 2 0 -0.0004 7 0 0 0 3.52E+07 2.80E+07 - - - 1.8286 0.999 221125_WJC_METTL3_EV_vs_WT_F01.15497.15497.2 0.117 12-Jul R.MIEFVVR[166.11].E "sp|O15042|SR140_HUMAN,tr|E7ET15|E7ET15_HUMAN" 2 902.4923 0.34 3881 15497 2 902.492109 452.2534 U2 snRNP-associated SURP motif-containing protein OS=Homo sapiens OX=9606 GN=U2SURP PE=1 SV=2 5.75 3205.7 - 704717 - - - -0.2438 - 1.389 0.306 - 201.8 1 2 0 -0.0002 7 0 0 0 9.07E+06 2.68E+07 - - - 2.3422 1 221125_WJC_METTL3_EV_vs_WT_F01.15498.15498.3 8.01E-07 15/64 R.IINEPTAAAIAYGLDK[136.11]K[136.11].G "sp|P54652|HSP72_HUMAN,sp|P11142|HSP7C_HUMAN,tr|E9PKE3|E9PKE3_HUMAN,tr|E9PN89|E9PN89_HUMAN,tr|E9PI65|E9PI65_HUMAN" 5 1803.0113 0.8 3882 15498 3 1803.010809 602.011 Heat shock-related 70 kDa protein 2 OS=Homo sapiens OX=9606 GN=HSPA2 PE=1 SV=1 6.07 3205.9 - 389897 - - - -0.2723 - 2.929 0.573 - 192.8 1 2 0 -0.0005 17 0 0 0 2.16E+07 2.70E+07 - - - 7.6432 0.9997 221125_WJC_METTL3_EV_vs_WT_F01.15503.15503.2 0.00181 18-Oct R.TVPLLLAESK[136.11].F sp|Q709C8|VP13C_HUMAN 1 1077.6525 0.51 3885 15503 2 1077.651366 539.8335 Vacuolar protein sorting-associated protein 13C OS=Homo sapiens OX=9606 GN=VPS13C PE=1 SV=1 5.66 3206.5 - 647210 - - - -1.0625 - 1.774 0.408 - 338.3 1 2 0 -0.0011 10 0 0 0 7.75E+06 1.51E+07 - - - 3.6542 0.9965 221125_WJC_METTL3_EV_vs_WT_F01.15504.15504.2 0.165 12-Jul R.MIEFVVR.E "sp|O15042|SR140_HUMAN,tr|E7ET15|E7ET15_HUMAN" 2 892.4841 0.36 3886 15504 2 892.484161 447.2493 U2 snRNP-associated SURP motif-containing protein OS=Homo sapiens OX=9606 GN=U2SURP PE=1 SV=2 5.75 3206.6 - 546285 - - - 0.1143 - 1.204 0.234 - 211.1 1 2 0 0.0001 7 0 0 0 8.98E+06 2.50E+07 - - - 1.3575 0.9998 221125_WJC_METTL3_EV_vs_WT_F01.15508.15508.3 9.33E-06 14/64 R.IINEPTAAAIAYGLDKK.G "sp|P54652|HSP72_HUMAN,sp|P11142|HSP7C_HUMAN,tr|E9PKE3|E9PKE3_HUMAN,tr|E9PN89|E9PN89_HUMAN,tr|E9PI65|E9PI65_HUMAN" 5 1786.9829 0.8 3888 15508 3 1786.984313 596.6682 Heat shock-related 70 kDa protein 2 OS=Homo sapiens OX=9606 GN=HSPA2 PE=1 SV=1 6.07 3207.2 - 406819 - - - 0.7907 - 2.602 0.337 - 54.4 1 2 0 0.0014 17 0 0 0 2.16E+07 2.70E+07 - - - 4.7127 0.9989 221125_WJC_METTL3_EV_vs_WT_F01.15519.15519.2 0.00206 12-Jul K.FGDFVLK[136.11].S "sp|P11172|UMPS_HUMAN,tr|F2Z303|F2Z303_HUMAN,tr|F2Z3P2|F2Z3P2_HUMAN,tr|F8WDG4|F8WDG4_HUMAN,tr|E9PFD2|E9PFD2_HUMAN" 5 832.4574 0.77 3895 15519 2 832.457793 417.236 Uridine 5'-monophosphate synthase OS=Homo sapiens OX=9606 GN=UMPS PE=1 SV=1 5.84 3208.5 - 450880 - - - 0.424 - 1.361 0.314 - 117.4 1 2 0 0.0004 7 0 0 0 3.92E+07 5.06E+07 - - - 2.3367 0.996 221125_WJC_METTL3_EV_vs_WT_F01.15520.15520.2 0.0328 24-Aug K.LGPGAGAGFGVLR.R "sp|Q9BUL5|PHF23_HUMAN,tr|I3L1N0|I3L1N0_HUMAN,tr|I3L410|I3L410_HUMAN,tr|I3L4Q4|I3L4Q4_HUMAN" 4 1170.6509 0.54 3896 15520 2 1170.65251 586.3327 PHD finger protein 23 OS=Homo sapiens OX=9606 GN=PHF23 PE=1 SV=1 9.75 3208.7 - 284194 - - - 1.3394 - 1.633 0.205 - 51.8 3 2 0 0.0016 13 0 0 0 8.47E+06 1.57E+07 - - - 1.6002 0.9764 221125_WJC_METTL3_EV_vs_WT_F01.15525.15525.2 0.0528 22-May R.EIFGLYGQTTGK[136.11].G "sp|Q9NR31|SAR1A_HUMAN,tr|H0Y5E8|H0Y5E8_HUMAN" 2 1320.6805 0.25 3899 15525 2 1320.682278 661.3475 GTP-binding protein SAR1a OS=Homo sapiens OX=9606 GN=SAR1A PE=1 SV=1 6.1 3209.3 - 84218.1 - - - 1.3334 - 1.061 0.173 - 49.3 2 2 0 0.0018 12 0 0 0 4.85E+05 1.97E+06 - - - 0.3396 0.994 221125_WJC_METTL3_EV_vs_WT_F01.15528.15528.2 0.387 12-Aug K.VFGIQLK.E "sp|Q9UNF1|MAGD2_HUMAN,tr|Q5H907|Q5H907_HUMAN,tr|Q5H909|Q5H909_HUMAN" 3 803.4905 1.49 3900 15528 2 803.490815 402.7525 Melanoma-associated antigen D2 OS=Homo sapiens OX=9606 GN=MAGED2 PE=1 SV=2 8.72 3209.7 - 1.21E+06 - - - 0.3609 - 1.195 0.19 - 191.2 1 2 0 0.0003 7 0 0 0 2.43E+07 1.63E+07 - - - 1.0087 0.9996 221125_WJC_METTL3_EV_vs_WT_F01.15535.15535.2 0.74 16-Oct R.TEIIILATR.T "sp|P23396|RS3_HUMAN,tr|H0YEU2|H0YEU2_HUMAN,tr|E9PL09|E9PL09_HUMAN,tr|E9PK82|E9PK82_HUMAN,tr|F2Z2S8|F2Z2S8_HUMAN,tr|H0YCJ7|H0YCJ7_HUMAN,tr|E9PQ96|E9PQ96_HUMAN,tr|E9PJH4|E9PJH4_HUMAN,tr|E9PPU1|E9PPU1_HUMAN,tr|H0YF32|H0YF32_HUMAN" 10 1028.623 0.89 3905 15535 2 1028.624044 515.3188 40S ribosomal protein S3 OS=Homo sapiens OX=9606 GN=RPS3 PE=1 SV=2 5.66 3210.6 - 7.82E+06 - - - 1.0188 - 2.038 0.349 - 474.5 1 2 0 0.001 9 0 0 0 5.10E+08 5.74E+08 - - - 3.6781 0.9967 221125_WJC_METTL3_EV_vs_WT_F01.15543.15543.2 5.16 14-Jun K.LFIGNLPR[166.11].E "sp|Q9BWF3|RBM4_HUMAN,sp|Q9BQ04|RBM4B_HUMAN,tr|E9PM61|E9PM61_HUMAN,tr|D6R9K7|D6R9K7_HUMAN,tr|J3QRR5|J3QRR5_HUMAN,tr|E9PB51|E9PB51_HUMAN,tr|U3KQD5|U3KQD5_HUMAN,tr|E9PLB0|E9PLB0_HUMAN" 8 938.5577 1.4 3911 15543 2 938.558017 470.2861 RNA-binding protein 4 OS=Homo sapiens OX=9606 GN=RBM4 PE=1 SV=1 9.75 3211.6 - 2.49E+06 - - - 0.3303 - 1.376 0.194 - 121.5 1 2 0 0.0003 8 0 0 0 5.42E+09 3.86E+09 - - - 1.4364 0.8458 221125_WJC_METTL3_EV_vs_WT_F01.15547.15547.2 0.31 12-Jul V.DEIIWVK[136.11].T sp|Q86U44|MTA70_HUMAN 1 909.5051 0.21 3915 15547 2 909.506217 455.7598 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 4.37 3211.9 - 710183 - - - 1.2072 - 1.557 0.179 - 236.5 1 1 0 0.0011 7 0 0 0 2.11E+07 9.94E+07 - - - 1.7657 0.9993 221125_WJC_METTL3_EV_vs_WT_F01.15548.15548.2 0.0597 18-Oct R.LPAAFAPLPR.V "sp|O14561|ACPM_HUMAN,tr|H3BNE8|H3BNE8_HUMAN,tr|H3BNK3|H3BNK3_HUMAN" 3 1051.6179 3.66 3916 15548 2 1051.618974 526.8162 "Acyl carrier protein, mitochondrial OS=Homo sapiens OX=9606 GN=NDUFAB1 PE=1 SV=3" 9.75 3212.1 - 241634 - - - 1.0679 - 2.113 0.263 - 313.5 1 2 0 0.0011 10 0 0 0 1.17E+07 3.21E+06 - - - 3.0714 0.9701 221125_WJC_METTL3_EV_vs_WT_F01.15551.15551.2 2.45 12-Jun R.R[166.11]TGDYLR[166.11].R "sp|Q93097|WNT2B_HUMAN,tr|Q5TEH8|Q5TEH8_HUMAN" 2 899.4728 0.13 3918 15551 2 899.47376 450.7437 Protein Wnt-2b OS=Homo sapiens OX=9606 GN=WNT2B PE=1 SV=2 8.75 3212.4 - 560788 - - - 1.0617 - 1.217 0.058 - 91.4 1 2 0 0.001 7 0 0 0 1.82E+06 1.37E+07 - - - 0.0914 0.9991 221125_WJC_METTL3_EV_vs_WT_F01.15553.15553.2 0.00492 16-Jul K.VIVPNMEFR[166.11].A sp|P55060|XPO2_HUMAN 1 1113.588 0.91 3919 15553 2 1113.58966 557.8013 Exportin-2 OS=Homo sapiens OX=9606 GN=CSE1L PE=1 SV=3 5.97 3212.6 - 608784 - - - 1.4718 - 1.419 0.388 - 177.1 1 2 0 0.0016 9 0 0 0 1.15E+08 1.27E+08 - - - 2.9187 0.9996 221125_WJC_METTL3_EV_vs_WT_F01.15556.15556.2 0.00232 16-Aug K.VIVPNMEFR.A sp|P55060|XPO2_HUMAN 1 1103.5798 0.9 3922 15556 2 1103.581106 552.7972 Exportin-2 OS=Homo sapiens OX=9606 GN=CSE1L PE=1 SV=3 5.97 3213 - 396169 - - - 1.2278 - 1.675 0.422 - 247 1 2 0 0.0014 9 0 0 0 1.15E+08 1.27E+08 - - - 3.6497 0.985 221125_WJC_METTL3_EV_vs_WT_F01.15557.15557.2 0.231 12-Jun R.ANIWLVR[166.11].G sp|Q68D91|MBLC2_HUMAN 1 880.5158 1.33 3923 15557 2 880.518236 441.2652 Acyl-coenzyme A thioesterase MBLAC2 OS=Homo sapiens OX=9606 GN=MBLAC2 PE=1 SV=3 9.79 3213.2 - 267384 - - - 2.7189 - 1.305 0.186 - 156.9 1 2 0 0.0024 7 0 0 0 5.93E+06 4.47E+06 - - - 1.2575 0.9954 221125_WJC_METTL3_EV_vs_WT_F01.15564.15564.2 0.236 12-Aug R.LSAIFLR.L "sp|Q86U86|PB1_HUMAN,tr|H0Y5B5|H0Y5B5_HUMAN,tr|E7EVG2|E7EVG2_HUMAN" 3 818.5014 1.21 3928 15564 2 818.501676 410.258 Protein polybromo-1 OS=Homo sapiens OX=9606 GN=PBRM1 PE=1 SV=1 9.75 3214.1 - 1.30E+06 - - - 0.3079 - 1.767 0.046 - 210.9 1 2 0 0.0003 7 0 0 0 6.47E+07 5.36E+07 - - - 1.1845 0.9994 221125_WJC_METTL3_EV_vs_WT_F01.15568.15568.2 0.03 18-Aug K.ILPEEITNLR.N sp|Q9H9A6|LRC40_HUMAN 1 1196.6765 1.36 3932 15568 2 1196.677785 599.3455 Leucine-rich repeat-containing protein 40 OS=Homo sapiens OX=9606 GN=LRRC40 PE=1 SV=1 4.53 3214.5 - 485281 - - - 1.0838 - 1.632 0.38 - 242.2 1 2 0 0.0013 10 0 0 0 1.04E+08 7.66E+07 - - - 3.2145 0.9982 221125_WJC_METTL3_EV_vs_WT_F01.15571.15571.2 0.144 12-Jul K.FGDFVLK.S "sp|P11172|UMPS_HUMAN,tr|F2Z303|F2Z303_HUMAN,tr|F2Z3P2|F2Z3P2_HUMAN,tr|F8WDG4|F8WDG4_HUMAN,tr|E9PFD2|E9PFD2_HUMAN" 5 824.4432 0.78 3933 15571 2 824.443371 413.2289 Uridine 5'-monophosphate synthase OS=Homo sapiens OX=9606 GN=UMPS PE=1 SV=1 5.84 3214.9 - 3.00E+06 - - - 0.1589 - 1.366 0.252 - 117.4 1 2 0 0.0001 7 0 0 0 3.92E+07 5.05E+07 - - - 1.8905 0.998 221125_WJC_METTL3_EV_vs_WT_F01.15572.15572.2 0.00854 14-Jul K.ELPTVVFR[166.11].A sp|Q9BVP2|GNL3_HUMAN 1 969.5523 0.93 3934 15572 2 969.5529 485.7834 Guanine nucleotide-binding protein-like 3 OS=Homo sapiens OX=9606 GN=GNL3 PE=1 SV=2 6.1 3215 - 1.21E+06 - - - 0.6323 - 1.375 0.256 - 214.5 1 2 0 0.0006 8 0 0 0 6.97E+07 7.49E+07 - - - 1.8921 0.886 221125_WJC_METTL3_EV_vs_WT_F01.15573.15573.2 0.127 16-Jul S.GVELGEESR[166.11].S "sp|O75410|TACC1_HUMAN,tr|E7EVI4|E7EVI4_HUMAN,tr|E5RJU4|E5RJU4_HUMAN,tr|E5RFM9|E5RFM9_HUMAN,tr|R4GMT7|R4GMT7_HUMAN,tr|H0YAY0|H0YAY0_HUMAN,tr|E7ET87|E7ET87_HUMAN" 7 984.4752 2.03 3935 15573 2 984.47555 493.2449 Transforming acidic coiled-coil-containing protein 1 OS=Homo sapiens OX=9606 GN=TACC1 PE=1 SV=2 4.25 3215.1 - 732639 - - - 0.3972 - 1.546 0.201 - 143.2 1 1 0 0.0004 9 0 0 0 1.05E+08 5.17E+07 - - - 1.7859 0.9996 221125_WJC_METTL3_EV_vs_WT_F01.15574.15574.2 0.000135 18-Sep K.ILPEEITNLR[166.11].N sp|Q9H9A6|LRC40_HUMAN 1 1206.6848 1.87 3936 15574 2 1206.686765 604.3497 Leucine-rich repeat-containing protein 40 OS=Homo sapiens OX=9606 GN=LRRC40 PE=1 SV=1 4.53 3215.2 - 544307 - - - 1.6632 - 1.785 0.452 - 345.8 1 2 0 0.002 10 0 0 0 1.02E+08 5.45E+07 - - - 3.9962 0.9992 221125_WJC_METTL3_EV_vs_WT_F01.15575.15575.2 0.0113 20-Jun R.VAYMNPIAMAR[166.11].S "sp|Q5BKY9|F133B_HUMAN,sp|Q8N9E0|F133A_HUMAN,tr|G3XAI9|G3XAI9_HUMAN" 3 1245.6238 0.61 3937 15575 2 1245.624639 623.8192 Protein FAM133B OS=Homo sapiens OX=9606 GN=FAM133B PE=1 SV=1 8.72 3215.4 - 138053 - - - 0.7105 - 1.387 0.37 - 106.9 1 2 0 0.0009 11 0 0 0 3.33E+06 5.50E+06 - - - 2.6585 0.9446 221125_WJC_METTL3_EV_vs_WT_F01.15580.15580.2 4.16 14-Jun K.LIYQWVSR.S "sp|Q9BRG1|VPS25_HUMAN,tr|K7ENE3|K7ENE3_HUMAN" 2 1063.5815 1.96 3940 15580 2 1063.579514 532.798 Vacuolar protein-sorting-associated protein 25 OS=Homo sapiens OX=9606 GN=VPS25 PE=1 SV=1 8.75 3216.1 - 592471 - - - -1.8344 - 1.216 0.037 - 98.1 1 2 0 -0.002 8 0 0 0 1.01E+07 5.15E+06 - - - -0.0965 0.9993 221125_WJC_METTL3_EV_vs_WT_F01.15590.15590.2 0.000431 16-Jul K.IYPVGYFTK.E "sp|Q15517|CDSN_HUMAN,tr|G8JLG2|G8JLG2_HUMAN,tr|Q2L6G8|Q2L6G8_HUMAN" 3 1086.575 1165.85 3949 15590 2 1086.574598 544.2948 Corneodesmosin OS=Homo sapiens OX=9606 GN=CDSN PE=1 SV=3 8.5 3217.2 - 3.73E+06 - - - -0.3543 - 1.417 0.361 - 160.8 1 2 0 -0.0004 9 0 0 0 2.73E+08 2.34E+05 - - - 2.7156 0.9761 221125_WJC_METTL3_EV_vs_WT_F01.15592.15592.2 1.02 12-Jul R.NLVLLVR[166.11].E sp|Q9H2W6|RM46_HUMAN 1 835.5519 1.21 3950 15592 2 835.551027 418.7832 "39S ribosomal protein L46, mitochondrial OS=Homo sapiens OX=9606 GN=MRPL46 PE=1 SV=1" 9.75 3217.4 - 2.14E+06 - - - -1.0364 - 1.424 0.001 - 267.6 1 2 0 -0.0009 7 0 0 0 5.55E+07 4.58E+07 - - - 0.1681 0.8168 221125_WJC_METTL3_EV_vs_WT_F01.15593.15593.2 12.1 12-Aug A.LDIILEK.M "sp|O75191|XYLB_HUMAN,sp|Q13616|CUL1_HUMAN,sp|Q96JB5|CK5P3_HUMAN,tr|A0A3B3IS07|A0A3B3IS07_HUMAN,tr|A0A0C4DGX4|A0A0C4DGX4_HUMAN,tr|A0A590UJ21|A0A590UJ21_HUMAN,tr|A0A590UJ50|A0A590UJ50_HUMAN,tr|A0A590UJR3|A0A590UJR3_HUMAN,tr|J3QRM1|J3QRM1_HUMAN,tr|A0A590UJC4|A0A590UJC4_HUMAN,tr|A0A590UK34|A0A590UK34_HUMAN" 11 842.5113 1.32 3951 15593 2 842.510075 422.2629 Xylulose kinase OS=Homo sapiens OX=9606 GN=XYLB PE=1 SV=3 4.37 3217.6 - 448084 - - - -1.4777 - 1.79 0.102 - 197.4 1 1 0 -0.0012 7 0 0 0 1.73E+07 1.30E+07 - - - 1.6388 0.9992 221125_WJC_METTL3_EV_vs_WT_F01.15595.15595.2 0.00124 20-Sep R.LVDAVLGAEIR.N "sp|Q9UBN7|HDAC6_HUMAN,tr|A6NDI8|A6NDI8_HUMAN,tr|A0A2R8Y758|A0A2R8Y758_HUMAN,tr|A0A2R8Y559|A0A2R8Y559_HUMAN,tr|A0A2R8YDE6|A0A2R8YDE6_HUMAN" 5 1154.6659 1.66 3953 15595 2 1154.662506 578.3402 Histone deacetylase 6 OS=Homo sapiens OX=9606 GN=HDAC6 PE=1 SV=2 4.37 3217.8 - 395952 - - - -2.9593 - 2.066 0.429 - 278.4 1 2 0 -0.0034 11 0 0 0 1.70E+07 1.02E+07 - - - 4.1715 0.916 221125_WJC_METTL3_EV_vs_WT_F01.15596.15596.2 0.0156 18-Aug A.MVWEGYNVVR.A "sp|O00746|NDKM_HUMAN,tr|Q4TT34|Q4TT34_HUMAN,tr|H0Y6J0|H0Y6J0_HUMAN,tr|F2Z2X0|F2Z2X0_HUMAN" 4 1251.607 2.02 3954 15596 2 1251.60624 626.8108 "Nucleoside diphosphate kinase, mitochondrial OS=Homo sapiens OX=9606 GN=NME4 PE=1 SV=1" 5.75 3218 - 132342 - - - -0.6296 - 1.379 0.287 - 254 1 1 0 -0.0008 10 0 0 0 2.46E+07 1.22E+07 - - - 2.0575 0.9257 221125_WJC_METTL3_EV_vs_WT_F01.15601.15601.2 0.0227 14-Jul F.AFLWAGGR[166.11].A "sp|Q00839|HNRPU_HUMAN,tr|A0A1W2PQL0|A0A1W2PQL0_HUMAN,tr|A0A1W2PPL4|A0A1W2PPL4_HUMAN,tr|A0A1W2PQ74|A0A1W2PQ74_HUMAN,tr|Q5RI18|Q5RI18_HUMAN,tr|A0A1W2PP35|A0A1W2PP35_HUMAN,tr|A0A1W2PPS1|A0A1W2PPS1_HUMAN,tr|A0A1W2PPH7|A0A1W2PPH7_HUMAN,tr|A0A1W2PP34|A0A1W2PP34_HUMAN,tr|A0A1W2PRI6|A0A1W2PRI6_HUMAN,tr|A0A1X7SBS1|A0A1X7SBS1_HUMAN,tr|A0A1W2PNG3|A0A1W2PNG3_HUMAN" 12 886.4689 1.1 3957 15601 2 886.467568 444.2417 Heterogeneous nuclear ribonucleoprotein U OS=Homo sapiens OX=9606 GN=HNRNPU PE=1 SV=6 9.79 3218.6 - 790325 - - - -1.4936 - 1.401 0.331 - 191.4 1 1 0 -0.0013 8 0 0 0 2.61E+09 2.38E+09 - - - 2.5023 0.9997 221125_WJC_METTL3_EV_vs_WT_F01.15603.15603.2 0.00026 18-Sep R.GYFEYIEENK.Y "sp|Q00839|HNRPU_HUMAN,tr|Q5RI18|Q5RI18_HUMAN,tr|A0A1W2PP35|A0A1W2PP35_HUMAN,tr|A0A1W2PPS1|A0A1W2PPS1_HUMAN,tr|A0A1W2PRI6|A0A1W2PRI6_HUMAN" 5 1290.5768 1.28 3959 15603 2 1290.575289 646.2957 Heterogeneous nuclear ribonucleoprotein U OS=Homo sapiens OX=9606 GN=HNRNPU PE=1 SV=6 4.25 3218.9 - 169884 - - - -1.1964 - 2.011 0.415 - 255.5 1 2 0 -0.0015 10 0 0 0 3.57E+06 2.78E+06 - - - 4.0558 0.9993 221125_WJC_METTL3_EV_vs_WT_F01.15607.15607.2 0.0657 20-Aug K.ILITTVPPNLR.K "sp|Q12905|ILF2_HUMAN,tr|B4DY09|B4DY09_HUMAN" 2 1235.7602 1.24 3961 15607 2 1235.760415 618.8874 Interleukin enhancer-binding factor 2 OS=Homo sapiens OX=9606 GN=ILF2 PE=1 SV=2 9.75 3219.3 - 859264 - - - 0.208 - 1.707 0.306 - 209.5 1 2 0 0.0003 11 0 0 0 4.26E+08 3.43E+08 - - - 2.7476 0.9992 221125_WJC_METTL3_EV_vs_WT_F01.15608.15608.2 0.0321 20-Oct K.ILITTVPPNLR[166.11].K "sp|Q12905|ILF2_HUMAN,tr|B4DY09|B4DY09_HUMAN" 2 1245.7684 1.24 3962 15608 2 1245.766709 623.8915 Interleukin enhancer-binding factor 2 OS=Homo sapiens OX=9606 GN=ILF2 PE=1 SV=2 9.75 3219.4 - 699087 - - - -1.3799 - 1.881 0.297 - 385.7 1 2 0 -0.0017 11 0 0 0 4.26E+08 3.43E+08 - - - 2.9433 0.9957 221125_WJC_METTL3_EV_vs_WT_F01.15609.15609.2 0.206 16-Jul R.LMGSILGVR[166.11].R "sp|Q15643|TRIPB_HUMAN,tr|H0YJ97|H0YJ97_HUMAN" 2 954.556 0.58 3963 15609 2 954.55414 478.2853 Thyroid receptor-interacting protein 11 OS=Homo sapiens OX=9606 GN=TRIP11 PE=1 SV=3 9.75 3219.5 - 3.63E+06 - - - -1.9402 - 1.589 0.186 - 124.5 1 2 0 -0.0019 9 0 0 0 1.13E+08 1.95E+08 - - - 1.754 0.9997 221125_WJC_METTL3_EV_vs_WT_F01.15610.15610.2 0.00882 20-Dec K.LLLIGDSGVGK.T "sp|P61006|RAB8A_HUMAN,sp|P51153|RAB13_HUMAN,sp|P61026|RAB10_HUMAN,sp|Q15286|RAB35_HUMAN,sp|Q9H0U4|RAB1B_HUMAN,sp|P59190|RAB15_HUMAN,sp|P62820|RAB1A_HUMAN,sp|Q92930|RAB8B_HUMAN,sp|Q92928|RAB1C_HUMAN,tr|H0YMN7|H0YMN7_HUMAN,tr|H0YL94|H0YL94_HUMAN,tr|A0A2R8YDI9|A0A2R8YDI9_HUMAN,tr|H0YNE9|H0YNE9_HUMAN,tr|G3V196|G3V196_HUMAN,tr|A0A2R8YFB8|A0A2R8YFB8_HUMAN,tr|H0YLJ8|H0YLJ8_HUMAN,tr|E9PLD0|E9PLD0_HUMAN,tr|E7END7|E7END7_HUMAN,tr|F5H157|F5H157_HUMAN" 19 1070.6336 1.07 3964 15610 2 1070.632585 536.3241 Ras-related protein Rab-8A OS=Homo sapiens OX=9606 GN=RAB8A PE=1 SV=1 5.84 3219.5 - 2.51E+06 - - - -0.9107 - 2.291 0.356 - 432.5 1 2 0 -0.001 11 0 0 0 7.43E+08 6.92E+08 - - - 3.9127 0.945 221125_WJC_METTL3_EV_vs_WT_F01.15611.15611.2 0.00664 14-Jul F.AFLWAGGR.A "sp|Q00839|HNRPU_HUMAN,tr|A0A1W2PQL0|A0A1W2PQL0_HUMAN,tr|A0A1W2PPL4|A0A1W2PPL4_HUMAN,tr|A0A1W2PQ74|A0A1W2PQ74_HUMAN,tr|Q5RI18|Q5RI18_HUMAN,tr|A0A1W2PP35|A0A1W2PP35_HUMAN,tr|A0A1W2PPS1|A0A1W2PPS1_HUMAN,tr|A0A1W2PPH7|A0A1W2PPH7_HUMAN,tr|A0A1W2PP34|A0A1W2PP34_HUMAN,tr|A0A1W2PRI6|A0A1W2PRI6_HUMAN,tr|A0A1X7SBS1|A0A1X7SBS1_HUMAN,tr|A0A1W2PNG3|A0A1W2PNG3_HUMAN" 12 876.4606 1.1 3965 15611 2 876.459038 439.2376 Heterogeneous nuclear ribonucleoprotein U OS=Homo sapiens OX=9606 GN=HNRNPU PE=1 SV=6 9.79 3219.6 - 693229 - - - -1.8073 - 1.523 0.364 - 209.3 1 1 0 -0.0016 8 0 0 0 2.61E+09 2.38E+09 - - - 2.9978 0.9867 221125_WJC_METTL3_EV_vs_WT_F01.15613.15613.2 4.59E-06 18-Oct A.MVWEGYNVVR[166.11].A "sp|O00746|NDKM_HUMAN,tr|Q4TT34|Q4TT34_HUMAN,tr|H0Y6J0|H0Y6J0_HUMAN,tr|F2Z2X0|F2Z2X0_HUMAN" 4 1261.6153 2.02 3967 15613 2 1261.616827 631.8149 "Nucleoside diphosphate kinase, mitochondrial OS=Homo sapiens OX=9606 GN=NME4 PE=1 SV=1" 5.75 3219.9 - 262430 - - - 1.2119 - 1.948 0.483 - 297 1 1 0 0.0015 10 0 0 0 2.46E+07 1.22E+07 - - - 4.4692 0.9839 221125_WJC_METTL3_EV_vs_WT_F01.15616.15616.2 0.177 12-Jun K.LFQLYPR[166.11].N sp|Q8IXM3|RM41_HUMAN 1 945.5312 1.43 3968 15616 2 945.529619 473.7729 "39S ribosomal protein L41, mitochondrial OS=Homo sapiens OX=9606 GN=MRPL41 PE=1 SV=1" 8.75 3220.4 - 3.53E+06 - - - -1.6277 - 1.263 0.117 - 123.4 1 2 0 -0.0015 7 0 0 0 2.61E+08 1.82E+08 - - - 0.6445 0.952 221125_WJC_METTL3_EV_vs_WT_F01.15617.15617.2 1.59 12-Jul R.NLVLLVR.E sp|Q9H2W6|RM46_HUMAN 1 825.5436 1.09 3969 15617 2 825.541868 413.7791 "39S ribosomal protein L46, mitochondrial OS=Homo sapiens OX=9606 GN=MRPL46 PE=1 SV=1" 9.75 3220.4 - 2.30E+06 - - - -2.1259 - 1.407 0.001 - 236 1 2 0 -0.0018 7 0 0 0 4.88E+07 4.47E+07 - - - 0.1298 0.9961 221125_WJC_METTL3_EV_vs_WT_F01.15618.15618.2 9.01E-05 14-Sep K.FC[160.03]ELLIGR.G "sp|O75179|ANR17_HUMAN,tr|H0YM23|H0YM23_HUMAN,tr|H0YLQ3|H0YLQ3_HUMAN" 3 1006.527 10.63 3970 15618 2 1006.522304 504.2708 Ankyrin repeat domain-containing protein 17 OS=Homo sapiens OX=9606 GN=ANKRD17 PE=1 SV=3 5.99 3220.5 - 805467 - - - -4.6526 - 1.924 0.37 - 325.9 1 2 0 -0.0047 8 0 0 0 2.70E+08 2.54E+07 - - - 3.746 0.9996 221125_WJC_METTL3_EV_vs_WT_F01.15621.15621.2 7.64E-06 18-Oct K.FAEAFEAIPR.A sp|P50990|TCPQ_HUMAN 1 1149.5819 0.4 3973 15621 2 1149.57885 575.7982 T-complex protein 1 subunit theta OS=Homo sapiens OX=9606 GN=CCT8 PE=1 SV=4 4.53 3220.9 - 369811 - - - -2.6175 - 2.189 0.527 - 347.4 1 2 0 -0.003 10 0 0 0 4.63E+08 1.15E+09 - - - 5.1193 0.9998 221125_WJC_METTL3_EV_vs_WT_F01.15622.15622.2 6.40E-05 18-Aug R.GYFEYIEENK[136.11].Y "sp|Q00839|HNRPU_HUMAN,tr|Q5RI18|Q5RI18_HUMAN,tr|A0A1W2PP35|A0A1W2PP35_HUMAN,tr|A0A1W2PPS1|A0A1W2PPS1_HUMAN,tr|A0A1W2PRI6|A0A1W2PRI6_HUMAN" 5 1298.591 1.28 3974 15622 2 1298.589251 650.3028 Heterogeneous nuclear ribonucleoprotein U OS=Homo sapiens OX=9606 GN=HNRNPU PE=1 SV=6 4.25 3221 - 305874 - - - -1.3723 - 1.915 0.477 - 162.9 1 2 0 -0.0018 10 0 0 0 3.57E+06 2.78E+06 - - - 4.3771 0.9999 221125_WJC_METTL3_EV_vs_WT_F01.15625.15625.2 0.00122 18-Dec K.FAEAFEAIPR[166.11].A sp|P50990|TCPQ_HUMAN 1 1159.5901 0.4 3975 15625 2 1159.589094 580.8023 T-complex protein 1 subunit theta OS=Homo sapiens OX=9606 GN=CCT8 PE=1 SV=4 4.53 3221.4 - 2.95E+06 - - - -0.8926 - 2.368 0.537 - 570.4 1 2 0 -0.001 10 0 0 0 4.63E+08 1.15E+09 - - - 5.4132 0.9218 221125_WJC_METTL3_EV_vs_WT_F01.15626.15626.2 4.58 14-May K.ADMVDGIK.E "sp|Q96JN8|NEUL4_HUMAN,tr|K7ESM1|K7ESM1_HUMAN,tr|K7ESJ6|K7ESJ6_HUMAN,tr|I3L2W2|I3L2W2_HUMAN,tr|I3L100|I3L100_HUMAN" 5 847.411 1.32 3976 15626 2 847.409742 424.7128 Neuralized-like protein 4 OS=Homo sapiens OX=9606 GN=NEURL4 PE=1 SV=2 4.21 3221.5 - 1.20E+06 - - - -1.4302 - 1.049 0.081 - 83.2 4 2 0 -0.0012 8 0 0 0 2.68E+07 2.04E+07 - - - -0.4858 0.9974 221125_WJC_METTL3_EV_vs_WT_F01.15627.15627.2 0.766 12-Jul R.LIFDNLK.K "sp|P05023|AT1A1_HUMAN,sp|P13637|AT1A3_HUMAN,sp|Q13733|AT1A4_HUMAN,sp|P50993|AT1A2_HUMAN,sp|P54707|AT12A_HUMAN,sp|P20648|ATP4A_HUMAN,tr|A0A0A0MT26|A0A0A0MT26_HUMAN,tr|H0Y7C1|H0Y7C1_HUMAN,tr|A0A2R8YEY8|A0A2R8YEY8_HUMAN,tr|B1AKY9|B1AKY9_HUMAN,tr|M0R116|M0R116_HUMAN" 11 861.496 1.26 3977 15627 2 861.495024 431.7553 Sodium\potassium-transporting ATPase subunit alpha-1 OS=Homo sapiens OX=9606 GN=ATP1A1 PE=1 SV=1 5.84 3221.6 - 967714 - - - -1.1376 - 1.337 0.245 - 119.7 1 2 0 -0.001 7 0 0 0 5.69E+07 4.50E+07 - - - 1.7705 0.9653 221125_WJC_METTL3_EV_vs_WT_F01.15630.15630.2 1.47 14-Jul K.LIPVLQVK[136.11].L sp|Q63ZY3|KANK2_HUMAN 1 916.6201 1.44 3980 15630 2 916.619806 459.3173 KN motif and ankyrin repeat domain-containing protein 2 OS=Homo sapiens OX=9606 GN=KANK2 PE=1 SV=1 8.75 3222 - 778780 - - - -0.3087 - 1.065 0.077 - 103.7 1 2 0 -0.0003 8 0 0 0 2.78E+07 1.92E+07 - - - -0.2004 0.9998 221125_WJC_METTL3_EV_vs_WT_F01.15631.15631.2 2.93E-05 14/20 R.LVDAVLGAEIR[166.11].N "sp|Q9UBN7|HDAC6_HUMAN,tr|A6NDI8|A6NDI8_HUMAN,tr|A0A2R8Y758|A0A2R8Y758_HUMAN,tr|A0A2R8Y559|A0A2R8Y559_HUMAN,tr|A0A2R8YDE6|A0A2R8YDE6_HUMAN" 5 1164.6742 1.66 3981 15631 2 1164.675602 583.3444 Histone deacetylase 6 OS=Homo sapiens OX=9606 GN=HDAC6 PE=1 SV=2 4.37 3222.1 - 551645 - - - 1.2098 - 2.299 0.474 - 514.2 1 2 0 0.0014 11 0 0 0 1.70E+07 1.02E+07 - - - 4.7936 0.9987 221125_WJC_METTL3_EV_vs_WT_F01.15632.15632.2 0.00253 14-Jul R.GFVLYPVK.Y sp|P62487|RPB7_HUMAN 1 921.5324 0.01 3982 15632 2 921.531593 461.7735 DNA-directed RNA polymerase II subunit RPB7 OS=Homo sapiens OX=9606 GN=POLR2G PE=1 SV=1 8.59 3222.2 - 362276 - - - -0.8649 - 1.494 0.268 - 159.1 1 2 0 -0.0008 8 0 0 0 2.45E+07 2.66E+09 - - - 2.231 0.9758 221125_WJC_METTL3_EV_vs_WT_F01.15633.15633.2 0.125 16-Aug K.LYENLGFVR[166.11].D "sp|Q147X3|NAA30_HUMAN,tr|J3KNC2|J3KNC2_HUMAN,tr|B4DK34|B4DK34_HUMAN" 3 1119.5952 0.59 3983 15633 2 1119.599299 560.8049 N-alpha-acetyltransferase 30 OS=Homo sapiens OX=9606 GN=NAA30 PE=1 SV=1 6 3222.4 - 346705 - - - 3.6477 - 1.36 0.198 - 188.2 1 2 0 0.0041 9 0 0 0 9.53E+06 1.61E+07 - - - 1.3917 0.9441 221125_WJC_METTL3_EV_vs_WT_F01.15645.15645.2 0.0517 14-Jun K.QMAFMLGR[166.11].H sp|Q13200|PSMD2_HUMAN 1 962.4705 0.92 3990 15645 2 962.46551 482.2426 26S proteasome non-ATPase regulatory subunit 2 OS=Homo sapiens OX=9606 GN=PSMD2 PE=1 SV=3 9.75 3223.8 - 1.38E+06 - - - -5.2344 - 1.119 0.299 - 102.9 1 2 0 -0.005 8 0 0 0 2.86E+07 3.11E+07 - - - 1.5869 0.9735 221125_WJC_METTL3_EV_vs_WT_F01.15646.15646.2 0.131 14-Aug S.DGGLVALR[166.11].N sp|P55290|CAD13_HUMAN 1 809.4635 0.46 3991 15646 2 809.462844 405.739 Cadherin-13 OS=Homo sapiens OX=9606 GN=CDH13 PE=1 SV=1 5.84 3223.9 - 913935 - - - -0.7758 - 1.846 0.316 - 268.4 1 1 0 -0.0006 8 0 0 0 1.09E+07 2.36E+07 - - - 3.2236 0.9985 221125_WJC_METTL3_EV_vs_WT_F01.15647.15647.2 0.00544 16-Sep K.VYEAVELLK.S sp|Q8TEQ6|GEMI5_HUMAN 1 1062.5961 999 3992 15647 2 1062.593448 532.3053 Gem-associated protein 5 OS=Homo sapiens OX=9606 GN=GEMIN5 PE=1 SV=3 4.53 3224.1 - 524106 - - - -2.5071 - 1.664 0.341 - 186.5 1 2 0 -0.0027 9 0 0 0 1.19E+07 0.00E+00 - - - 3.032 0.9969 221125_WJC_METTL3_EV_vs_WT_F01.15651.15651.2 0.16 14-Aug R.LISLPLSR[166.11].L "sp|Q9NRG0|CHRC1_HUMAN,tr|E5RGS9|E5RGS9_HUMAN" 2 907.573 1.1 3994 15651 2 907.571501 454.7938 Chromatin accessibility complex protein 1 OS=Homo sapiens OX=9606 GN=CHRAC1 PE=1 SV=1 9.75 3224.6 - 1.23E+06 - - - -1.677 - 1.709 0.166 - 178.4 1 2 0 -0.0015 8 0 0 0 9.76E+07 8.87E+07 - - - 1.8829 0.9919 221125_WJC_METTL3_EV_vs_WT_F01.15661.15661.2 0.345 14-Jul K.LLTYEFVK[136.11].Q sp|Q9Y5V3|MAGD1_HUMAN 1 1019.5783 2.27 3999 15661 2 1019.578135 510.7964 Melanoma-associated antigen D1 OS=Homo sapiens OX=9606 GN=MAGED1 PE=1 SV=3 6 3225.9 - 1.05E+06 - - - -0.1461 - 1.444 0.083 - 102.4 1 2 0 -0.0001 8 0 0 0 1.23E+08 5.40E+07 - - - 0.7621 0.9996 221125_WJC_METTL3_EV_vs_WT_F01.15664.15664.3 0.0189 Dec-36 K.FAEAFEAIPR[166.11].A sp|P50990|TCPQ_HUMAN 1 1159.5901 0.66 4002 15664 3 1159.58852 387.5373 T-complex protein 1 subunit theta OS=Homo sapiens OX=9606 GN=CCT8 PE=1 SV=4 4.53 3226.3 - 785187 - - - -1.3876 - 1.892 0.334 - 233.9 1 2 0 -0.0016 10 0 0 0 1.24E+07 1.86E+07 - - - 4.1255 0.9943 221125_WJC_METTL3_EV_vs_WT_F01.15668.15668.2 0.202 12-Jun K.LQLVVLR.D "sp|Q9UDY2|ZO2_HUMAN,tr|A0A3B3IT83|A0A3B3IT83_HUMAN,tr|A0A2R8YDH4|A0A2R8YDH4_HUMAN,tr|A0A3B3ISF1|A0A3B3ISF1_HUMAN,tr|A0A1B0GTW1|A0A1B0GTW1_HUMAN,tr|A0A3B3ISZ5|A0A3B3ISZ5_HUMAN,tr|A0A3B3IRV6|A0A3B3IRV6_HUMAN,tr|A0A3B3IU51|A0A3B3IU51_HUMAN,tr|A0A3B3IRI3|A0A3B3IRI3_HUMAN,tr|A0A3B3ITE1|A0A3B3ITE1_HUMAN" 10 839.5593 1.07 4004 15668 2 839.558152 420.7869 Tight junction protein ZO-2 OS=Homo sapiens OX=9606 GN=TJP2 PE=1 SV=2 9.75 3226.8 - 767623 - - - -1.3352 - 1.501 0.126 - 112.7 1 2 0 -0.0011 7 0 0 0 1.86E+07 1.75E+07 - - - 1.2581 0.9937 221125_WJC_METTL3_EV_vs_WT_F01.15669.15669.2 0.0347 14-Jun R.WLPEEDFR[166.11].R sp|Q8IXT5|RB12B_HUMAN 1 1100.5166 1.13 4005 15669 2 1100.513208 551.2656 RNA-binding protein 12B OS=Homo sapiens OX=9606 GN=RBM12B PE=1 SV=2 4.14 3226.9 - 404492 - - - -3.1094 - 1.177 0.354 - 141.4 1 2 0 -0.0034 8 0 0 0 1.79E+07 1.59E+07 - - - 2.1461 0.9922 221125_WJC_METTL3_EV_vs_WT_F01.15673.15673.2 0.436 12-Jul K.ILPDILK[136.11].K "sp|P35520|CBS_HUMAN,tr|C9JMA6|C9JMA6_HUMAN" 2 818.5357 0.34 4007 15673 2 818.534126 410.2751 Cystathionine beta-synthase OS=Homo sapiens OX=9606 GN=CBS PE=1 SV=2 5.84 3227.4 - 909686 - - - -1.912 - 1.303 0.191 - 106.9 1 2 0 -0.0016 7 0 0 0 3.16E+07 9.22E+07 - - - 1.2899 0.9978 221125_WJC_METTL3_EV_vs_WT_F01.15686.15686.2 0.104 14-Jun M.VLLTMIAR.V sp|O75396|SC22B_HUMAN 1 915.5576 1.03 4016 15686 2 915.556698 458.7861 Vesicle-trafficking protein SEC22b OS=Homo sapiens OX=9606 GN=SEC22B PE=1 SV=5 9.72 3229 - 2.29E+06 - - - -0.9404 - 1.348 0.259 - 128.4 1 2 0 -0.0009 8 0 0 0 9.30E+07 9.06E+07 - - - 1.8543 0.9971 221125_WJC_METTL3_EV_vs_WT_F01.15687.15687.2 0.0313 14-Oct R.LEEIPLIK[136.11].S sp|Q14152|EIF3A_HUMAN 1 961.5939 1.05 4017 15687 2 961.590926 481.8042 Eukaryotic translation initiation factor 3 subunit A OS=Homo sapiens OX=9606 GN=EIF3A PE=1 SV=1 4.53 3229.1 - 1.43E+06 - - - -3.1281 - 1.831 0.27 - 246.2 1 2 0 -0.003 8 0 0 0 9.05E+07 8.63E+07 - - - 2.8585 0.9959 221125_WJC_METTL3_EV_vs_WT_F01.15688.15688.2 0.00136 16-Aug K.YEDGIALLR.N "sp|Q9UJX3|APC7_HUMAN,tr|H0YIW2|H0YIW2_HUMAN" 2 1048.5553 0.18 4018 15688 2 1048.559066 525.2849 Anaphase-promoting complex subunit 7 OS=Homo sapiens OX=9606 GN=ANAPC7 PE=1 SV=4 4.37 3229.2 - 781247 - - - 3.5821 - 1.465 0.367 - 140.3 1 2 0 0.0038 9 0 0 0 1.59E+07 8.71E+07 - - - 2.8552 0.9998 221125_WJC_METTL3_EV_vs_WT_F01.15689.15689.2 1.39E-05 20-Dec M.PMFIVNTNVPR.A sp|P14174|MIF_HUMAN 1 1286.6805 0.84 4019 15689 2 1286.682538 644.3475 Macrophage migration inhibitory factor OS=Homo sapiens OX=9606 GN=MIF PE=1 SV=4 10.18 3229.4 - 301189 - - - 1.5629 - 2.38 0.552 - 559.1 1 2 0 0.002 11 0 0 0 1.80E+07 2.14E+07 - - - 5.4632 0.9991 221125_WJC_METTL3_EV_vs_WT_F01.15690.15690.2 0.00323 18-Aug K.ILVEEMAPLK.G "sp|Q16670|ZSC26_HUMAN,tr|A0A087WXM4|A0A087WXM4_HUMAN,tr|A0A024RCN4|A0A024RCN4_HUMAN,tr|A0A087X2F1|A0A087X2F1_HUMAN" 4 1141.6417 999 4020 15690 2 1141.643522 571.8281 Zinc finger and SCAN domain-containing protein 26 OS=Homo sapiens OX=9606 GN=ZSCAN26 PE=1 SV=2 4.53 3229.5 - 229870 - - - 1.6117 - 1.556 0.377 - 139.7 1 2 0 0.0018 10 0 0 0 2.99E+06 0.00E+00 - - - 3.059 0.9849 221125_WJC_METTL3_EV_vs_WT_F01.15695.15695.2 0.117 12-Jun K.FAPFEIK[136.11].E "sp|Q13111|CAF1A_HUMAN,tr|K7EPA1|K7EPA1_HUMAN" 2 858.4731 1.23 4023 15695 2 858.474163 430.2438 Chromatin assembly factor 1 subunit A OS=Homo sapiens OX=9606 GN=CHAF1A PE=1 SV=3 6 3230.1 - 944937 - - - 1.2499 - 1.327 0.091 - 94.3 1 2 0 0.0011 7 0 0 0 3.39E+07 2.76E+07 - - - 0.6092 0.9661 221125_WJC_METTL3_EV_vs_WT_F01.15696.15696.3 1.12 Sep-40 K.ILITTVPPNLR[166.11].K "sp|Q12905|ILF2_HUMAN,tr|B4DY09|B4DY09_HUMAN" 2 1245.7684 1.09 4024 15696 3 1245.768041 416.2634 Interleukin enhancer-binding factor 2 OS=Homo sapiens OX=9606 GN=ILF2 PE=1 SV=2 9.75 3230.2 - 421033 - - - -0.3107 - 1.699 0.093 - 169.2 1 2 0 -0.0004 11 0 0 0 2.86E+07 2.61E+07 - - - 1.0825 0.9896 221125_WJC_METTL3_EV_vs_WT_F01.15700.15700.2 0.00887 14-Jul R.LEEIPLIK.S sp|Q14152|EIF3A_HUMAN 1 953.5797 1.05 4026 15700 2 953.582597 477.7971 Eukaryotic translation initiation factor 3 subunit A OS=Homo sapiens OX=9606 GN=EIF3A PE=1 SV=1 4.53 3230.8 - 2.17E+06 - - - 3.0024 - 1.536 0.183 - 113.7 1 2 0 0.0029 8 0 0 0 9.05E+07 8.61E+07 - - - 1.6861 0.9987 221125_WJC_METTL3_EV_vs_WT_F01.15704.15704.2 0.956 14-Jul K.LFIGNLPR.E "sp|Q9BWF3|RBM4_HUMAN,sp|Q9BQ04|RBM4B_HUMAN,tr|E9PM61|E9PM61_HUMAN,tr|D6R9K7|D6R9K7_HUMAN,tr|J3QRR5|J3QRR5_HUMAN,tr|E9PB51|E9PB51_HUMAN,tr|U3KQD5|U3KQD5_HUMAN,tr|E9PLB0|E9PLB0_HUMAN" 8 928.5494 1.4 4029 15704 2 928.549408 465.282 RNA-binding protein 4 OS=Homo sapiens OX=9606 GN=RBM4 PE=1 SV=1 9.75 3231.3 - 4.86E+07 - - - -0.0312 - 1.555 0.236 - 169.1 1 2 0 0 8 0 0 0 5.42E+09 3.86E+09 - - - 2.1156 0.994 221125_WJC_METTL3_EV_vs_WT_F01.15706.15706.2 0.00348 16-Jul K.AFIGFEGVK.G sp|P15924|DESP_HUMAN 1 966.5175 2.72 4030 15706 2 966.51367 484.266 Desmoplakin OS=Homo sapiens OX=9606 GN=DSP PE=1 SV=3 6.05 3231.5 - 434108 - - - -3.9296 - 1.38 0.373 - 106.3 1 2 0 -0.0038 9 0 0 0 1.12E+08 4.10E+07 - - - 2.7266 0.9995 221125_WJC_METTL3_EV_vs_WT_F01.15707.15707.2 2.99E-06 20-Oct M.PMFIVNTNVPR[166.11].A sp|P14174|MIF_HUMAN 1 1296.6888 0.84 4031 15707 2 1296.68533 649.3517 Macrophage migration inhibitory factor OS=Homo sapiens OX=9606 GN=MIF PE=1 SV=4 10.18 3231.6 - 500567 - - - -2.6737 - 2.051 0.491 - 418 1 2 0 -0.0035 11 0 0 0 1.80E+07 2.14E+07 - - - 4.6097 0.9992 221125_WJC_METTL3_EV_vs_WT_F01.15715.15715.2 0.0866 18-Sep K.AMTILLEEAK.A "sp|P55265|DSRAD_HUMAN,tr|A0A3B3ITG9|A0A3B3ITG9_HUMAN,tr|A0A3B3IRQ9|A0A3B3IRQ9_HUMAN,tr|A0A3B3ISU1|A0A3B3ISU1_HUMAN,tr|A0A7P0Z4K3|A0A7P0Z4K3_HUMAN,tr|A0A3B3ISX1|A0A3B3ISX1_HUMAN,tr|A0A7P0Z4F9|A0A7P0Z4F9_HUMAN" 7 1117.6053 0.72 4037 15715 2 1117.605228 559.8099 Double-stranded RNA-specific adenosine deaminase OS=Homo sapiens OX=9606 GN=ADAR PE=1 SV=4 4.53 3232.6 - 366703 - - - -0.0617 - 1.579 0.31 - 199.3 1 2 0 -0.0001 10 0 0 0 5.19E+07 7.23E+07 - - - 2.6057 0.9892 221125_WJC_METTL3_EV_vs_WT_F01.15719.15719.2 9.08 12-Jul M.LPLSLLK.T "sp|Q9Y4Z0|LSM4_HUMAN,sp|Q969I6|S38A4_HUMAN,tr|F8VQY9|F8VQY9_HUMAN,tr|M0QXB0|M0QXB0_HUMAN,tr|V9GZ56|V9GZ56_HUMAN" 5 782.5266 145.81 4040 15719 2 782.525886 392.2706 U6 snRNA-associated Sm-like protein LSm4 OS=Homo sapiens OX=9606 GN=LSM4 PE=1 SV=1 8.75 3233 - 9.66E+06 - - - -0.8818 - 1.618 0.012 - 173.5 1 2 0 -0.0007 7 0 0 0 2.11E+08 1.45E+06 - - - 0.6541 0.9994 221125_WJC_METTL3_EV_vs_WT_F01.15722.15722.2 2.77E-05 16-Sep K.GPLMMYISK[136.11].M sp|P13639|EF2_HUMAN 1 1046.5384 0.38 4042 15722 2 1046.535617 524.2765 Elongation factor 2 OS=Homo sapiens OX=9606 GN=EEF2 PE=1 SV=4 8.59 3233.4 - 576038 - - - -2.6688 - 1.875 0.473 - 321.9 1 2 0 -0.0028 9 0 0 0 5.95E+07 1.56E+08 - - - 4.3523 0.9984 221125_WJC_METTL3_EV_vs_WT_F01.15723.15723.2 0.0657 18-Sep K.AMTILLEEAK[136.11].A "sp|P55265|DSRAD_HUMAN,tr|A0A3B3ITG9|A0A3B3ITG9_HUMAN,tr|A0A3B3IRQ9|A0A3B3IRQ9_HUMAN,tr|A0A3B3ISU1|A0A3B3ISU1_HUMAN,tr|A0A7P0Z4K3|A0A7P0Z4K3_HUMAN,tr|A0A3B3ISX1|A0A3B3ISX1_HUMAN,tr|A0A7P0Z4F9|A0A7P0Z4F9_HUMAN" 7 1125.6195 0.72 4043 15723 2 1125.616596 563.817 Double-stranded RNA-specific adenosine deaminase OS=Homo sapiens OX=9606 GN=ADAR PE=1 SV=4 4.53 3233.5 - 767745 - - - -2.5772 - 1.824 0.316 - 277 1 2 0 -0.0029 10 0 0 0 5.19E+07 7.26E+07 - - - 3.0517 0.9893 221125_WJC_METTL3_EV_vs_WT_F01.15725.15725.2 0.138 22-May R.IVNEGGIDPLLR[166.11].G sp|Q92626|PXDN_HUMAN 1 1304.7328 1.57 4045 15725 2 1304.730308 653.3737 Peroxidasin homolog OS=Homo sapiens OX=9606 GN=PXDN PE=1 SV=2 4.37 3233.7 - 141881 - - - -1.8877 - 1.276 0.203 - 68 2 2 0 -0.0025 12 0 0 0 2.81E+06 1.79E+06 - - - 1.0464 0.9996 221125_WJC_METTL3_EV_vs_WT_F01.15738.15738.2 0.00405 20-Oct K.C[160.03]ILVASPGFVR[166.11].E sp|Q9BRX2|PELO_HUMAN 1 1227.6673 0.33 4052 15738 2 1227.667652 614.8409 Protein pelota homolog OS=Homo sapiens OX=9606 GN=PELO PE=1 SV=2 8.25 3235.4 - 377268 - - - 0.259 - 2.006 0.324 - 307.4 1 2 0 0.0003 11 0 0 0 3.59E+06 1.08E+07 - - - 3.3172 0.9997 221125_WJC_METTL3_EV_vs_WT_F01.15741.15741.2 0.00224 18-Oct K.FLDGIYVSEK[136.11].G "sp|P32969|RL9_HUMAN,tr|H0Y9R4|H0Y9R4_HUMAN,tr|D6RAN4|D6RAN4_HUMAN,tr|H0Y9V9|H0Y9V9_HUMAN,tr|A0A2R8Y5Y7|A0A2R8Y5Y7_HUMAN" 5 1177.611 0.77 4055 15741 2 1177.611945 589.8128 60S ribosomal protein L9 OS=Homo sapiens OX=9606 GN=RPL9 PE=1 SV=1 4.37 3235.8 - 476036 - - - 0.7677 - 1.781 0.413 - 222 1 2 0 0.0009 10 0 0 0 2.13E+07 2.75E+07 - - - 3.7022 0.9921 221125_WJC_METTL3_EV_vs_WT_F01.15745.15745.2 1.03 12-Jun K.LIIFDAR.Q "sp|Q13613|MTMR1_HUMAN,tr|Q8NEC6|Q8NEC6_HUMAN,tr|F8WA39|F8WA39_HUMAN,tr|H0YDX3|H0YDX3_HUMAN" 4 846.4963 0.55 4057 15745 2 846.497577 424.2554 Myotubularin-related protein 1 OS=Homo sapiens OX=9606 GN=MTMR1 PE=1 SV=4 5.84 3236.3 - 528160 - - - 1.4625 - 1.291 0.175 - 122.8 1 2 0 0.0012 7 0 0 0 2.67E+07 4.86E+07 - - - 1.1425 0.9996 221125_WJC_METTL3_EV_vs_WT_F01.15748.15748.2 0.000185 18-Oct K.FLDGIYVSEK.G "sp|P32969|RL9_HUMAN,tr|H0Y9R4|H0Y9R4_HUMAN,tr|D6RAN4|D6RAN4_HUMAN,tr|H0Y9V9|H0Y9V9_HUMAN,tr|A0A2R8Y5Y7|A0A2R8Y5Y7_HUMAN" 5 1169.5968 0.77 4058 15748 2 1169.597636 585.8057 60S ribosomal protein L9 OS=Homo sapiens OX=9606 GN=RPL9 PE=1 SV=1 4.37 3236.7 - 495481 - - - 0.6797 - 1.694 0.388 - 233.4 1 2 0 0.0008 10 0 0 0 2.13E+07 2.77E+07 - - - 3.3778 0.9984 221125_WJC_METTL3_EV_vs_WT_F01.15749.15749.2 0.0771 16-Aug R.LLGLEEQLR.A "sp|P28290|ITPI2_HUMAN,tr|E9PHV5|E9PHV5_HUMAN,tr|E7EUL7|E7EUL7_HUMAN" 3 1069.6132 2.46 4059 15749 2 1069.613342 535.8139 Protein ITPRID2 OS=Homo sapiens OX=9606 GN=ITPRID2 PE=1 SV=3 4.53 3236.8 - 557582 - - - 0.1711 - 1.472 0.245 - 167.1 1 2 0 0.0002 9 0 0 0 1.20E+07 4.89E+06 - - - 1.969 0.9962 221125_WJC_METTL3_EV_vs_WT_F01.15754.15754.2 0.0743 16-Sep K.VVDVLDSIK[136.11].T sp|P00918|CAH2_HUMAN 1 994.579 0.86 4062 15754 2 994.580239 498.2968 Carbonic anhydrase 2 OS=Homo sapiens OX=9606 GN=CA2 PE=1 SV=2 4.21 3237.5 - 461782 - - - 1.2337 - 1.527 0.18 - 200.7 1 2 0 0.0012 9 0 0 0 3.22E+07 3.74E+07 - - - 1.5947 0.9944 221125_WJC_METTL3_EV_vs_WT_F01.15755.15755.2 0.00107 20-Aug K.C[160.03]ILVASPGFVR.E sp|Q9BRX2|PELO_HUMAN 1 1217.6591 0.34 4063 15755 2 1217.662931 609.8368 Protein pelota homolog OS=Homo sapiens OX=9606 GN=PELO PE=1 SV=2 8.25 3237.6 - 187398 - - - 3.1758 - 1.806 0.226 - 194.1 1 2 0 0.0039 11 0 0 0 3.59E+06 1.05E+07 - - - 2.3081 0.9988 221125_WJC_METTL3_EV_vs_WT_F01.15758.15758.2 0.033 18-Jul K.LLADELISPK[136.11].D "sp|Q93100|KPBB_HUMAN,tr|I3L0Z1|I3L0Z1_HUMAN" 2 1105.6474 1.17 4066 15758 2 1105.647051 553.831 Phosphorylase b kinase regulatory subunit beta OS=Homo sapiens OX=9606 GN=PHKB PE=1 SV=3 4.37 3238 - 235125 - - - -0.3392 - 1.441 0.292 - 113 1 2 0 -0.0004 10 0 0 0 4.94E+07 4.23E+07 - - - 2.2174 0.9988 221125_WJC_METTL3_EV_vs_WT_F01.15764.15764.2 0.00356 16-Jul R.LLSVLATVK.Q sp|O75063|XYLK_HUMAN 1 942.6114 1.43 4070 15764 2 942.613249 472.313 Glycosaminoglycan xylosylkinase OS=Homo sapiens OX=9606 GN=FAM20B PE=1 SV=1 8.75 3238.7 - 655170 - - - 1.9955 - 1.483 0.379 - 68.5 1 2 0 0.0019 9 0 0 0 2.77E+07 1.94E+07 - - - 2.9798 0.9989 221125_WJC_METTL3_EV_vs_WT_F01.15765.15765.2 0.0476 18-Oct K.LLADELISPK.D "sp|Q93100|KPBB_HUMAN,tr|I3L0Z1|I3L0Z1_HUMAN" 2 1097.6332 1.17 4071 15765 2 1097.631742 549.8239 Phosphorylase b kinase regulatory subunit beta OS=Homo sapiens OX=9606 GN=PHKB PE=1 SV=3 4.37 3238.9 - 340066 - - - -1.352 - 1.904 0.242 - 223 1 2 0 -0.0015 10 0 0 0 4.96E+07 4.23E+07 - - - 2.6254 0.9995 221125_WJC_METTL3_EV_vs_WT_F01.15766.15766.2 0.00218 16-Aug K.FLADDFDVK[136.11].E sp|P83436|COG7_HUMAN 1 1076.527 0.69 4072 15766 2 1076.525416 539.2708 Conserved oligomeric Golgi complex subunit 7 OS=Homo sapiens OX=9606 GN=COG7 PE=1 SV=1 3.93 3239 - 297999 - - - -1.45 - 1.458 0.445 - 153.9 1 2 0 -0.0016 9 0 0 0 5.49E+06 7.96E+06 - - - 3.4182 0.9964 221125_WJC_METTL3_EV_vs_WT_F01.15770.15770.2 0.164 18-Jul K.IPVSGPFLVK[136.11].T "sp|O00425|IF2B3_HUMAN,tr|F8WD15|F8WD15_HUMAN" 2 1063.6521 1.42 4074 15770 2 1063.65114 532.8333 Insulin-like growth factor 2 mRNA-binding protein 3 OS=Homo sapiens OX=9606 GN=IGF2BP3 PE=1 SV=2 8.75 3239.5 - 575119 - - - -0.9195 - 1.422 0.194 - 107 1 2 0 -0.001 10 0 0 0 2.99E+08 2.10E+08 - - - 1.4563 0.9978 221125_WJC_METTL3_EV_vs_WT_F01.15773.15773.2 0.0252 14-Jun K.FYSFALDK.T sp|Q96T58|MINT_HUMAN 1 989.4858 0.15 4077 15773 2 989.485721 495.7502 Msx2-interacting protein OS=Homo sapiens OX=9606 GN=SPEN PE=1 SV=1 5.83 3239.8 - 653700 - - - -0.1142 - 1.238 0.272 - 84.4 1 2 0 -0.0001 8 0 0 0 3.50E+07 2.33E+08 - - - 1.6939 0.9939 221125_WJC_METTL3_EV_vs_WT_F01.15777.15777.2 0.693 14-Jul R.LMGLEALK.S "sp|P48643|TCPE_HUMAN,tr|D6RIZ7|D6RIZ7_HUMAN,tr|E7ENZ3|E7ENZ3_HUMAN,tr|H0Y914|H0Y914_HUMAN" 4 873.4994 0.53 4079 15777 2 873.500005 437.757 T-complex protein 1 subunit epsilon OS=Homo sapiens OX=9606 GN=CCT5 PE=1 SV=1 6 3240.4 - 3.62E+07 - - - 0.7212 - 1.276 0.176 - 133.5 1 2 0 0.0006 8 0 0 0 1.15E+09 2.16E+09 - - - 1.0758 0.995 221125_WJC_METTL3_EV_vs_WT_F01.15786.15786.2 0.00299 16-Aug K.GYGFVEYMK.K sp|Q9HCJ3|RAVR2_HUMAN 1 1092.495 1.11 4084 15786 2 1092.490193 547.2548 Ribonucleoprotein PTB-binding 2 OS=Homo sapiens OX=9606 GN=RAVER2 PE=1 SV=2 6 3241.5 - 200080 - - - -4.4165 - 1.535 0.403 - 184.6 1 2 0 -0.0048 9 0 0 0 1.02E+07 9.16E+06 - - - 3.2558 0.8953 221125_WJC_METTL3_EV_vs_WT_F01.15787.15787.2 1.1 12-May R.LASLLFK.R sp|Q13064|MKRN3_HUMAN 1 790.4953 0.97 4085 15787 2 790.497133 396.2549 Probable E3 ubiquitin-protein ligase makorin-3 OS=Homo sapiens OX=9606 GN=MKRN3 PE=1 SV=1 8.75 3241.7 - 160142 - - - 2.3492 - 1.313 0.028 - 54.3 7 2 0 0.0019 7 0 0 0 1.12E+07 1.15E+07 - - - -0.2674 0.9999 221125_WJC_METTL3_EV_vs_WT_F01.15790.15790.2 0.0103 20-Nov K.NSLESYAFNMK[136.11].A "sp|P11142|HSP7C_HUMAN,tr|E9PNE6|E9PNE6_HUMAN,tr|A8K7Q2|A8K7Q2_HUMAN,tr|E9PKE3|E9PKE3_HUMAN,tr|E9PM13|E9PM13_HUMAN,tr|E9PS65|E9PS65_HUMAN" 6 1310.6056 0.1 4088 15790 2 1310.605677 656.3101 Heat shock cognate 71 kDa protein OS=Homo sapiens OX=9606 GN=HSPA8 PE=1 SV=1 6 3242.1 - 198151 - - - 0.0298 - 2.289 0.443 - 525.2 1 2 0 0 11 0 0 0 1.52E+06 1.50E+07 - - - 4.5532 0.9993 221125_WJC_METTL3_EV_vs_WT_F01.15793.15793.2 0.0782 16-Sep R.IGLINDMVR.F sp|Q14152|EIF3A_HUMAN 1 1029.5641 1.36 4089 15793 2 1029.564721 515.7893 Eukaryotic translation initiation factor 3 subunit A OS=Homo sapiens OX=9606 GN=EIF3A PE=1 SV=1 5.84 3242.5 - 3.09E+06 - - - 0.6022 - 1.89 0.266 - 232 1 2 0 0.0006 9 0 0 0 6.00E+07 4.42E+07 - - - 2.8471 0.9991 221125_WJC_METTL3_EV_vs_WT_F01.15794.15794.2 0.082 18-Sep K.IPVSGPFLVK.T "sp|O00425|IF2B3_HUMAN,tr|F8WD15|F8WD15_HUMAN" 2 1055.6379 1.43 4090 15794 2 1055.637583 528.8262 Insulin-like growth factor 2 mRNA-binding protein 3 OS=Homo sapiens OX=9606 GN=IGF2BP3 PE=1 SV=2 8.75 3242.5 - 2.24E+06 - - - -0.3173 - 1.63 0.28 - 241.4 1 2 0 -0.0003 10 0 0 0 2.99E+08 2.10E+08 - - - 2.4728 0.9948 221125_WJC_METTL3_EV_vs_WT_F01.15801.15801.2 0.193 12-Jul R.LSAILFK[136.11].L "sp|Q9NSV4|DIAP3_HUMAN,sp|Q12830|BPTF_HUMAN,tr|E9PE19|E9PE19_HUMAN,tr|J3KSK9|J3KSK9_HUMAN,tr|J3QQQ8|J3QQQ8_HUMAN,tr|E7ETD6|E7ETD6_HUMAN,tr|A0A2R8Y7Q1|A0A2R8Y7Q1_HUMAN" 7 798.5095 0.97 4095 15801 2 798.509166 400.262 Protein diaphanous homolog 3 OS=Homo sapiens OX=9606 GN=DIAPH3 PE=1 SV=4 8.75 3243.4 - 453632 - - - -0.3882 - 1.605 0.092 - 103.7 2 2 0 -0.0003 7 0 0 0 1.12E+07 1.15E+07 - - - 1.0851 0.9875 221125_WJC_METTL3_EV_vs_WT_F01.15802.15802.2 0.0669 14-Aug R.LIGWGQIR[166.11].R "sp|Q2VIR3|IF2GL_HUMAN,sp|P41091|IF2G_HUMAN" 2 951.553 0.98 4096 15802 2 951.55278 476.7838 Eukaryotic translation initiation factor 2 subunit 3B OS=Homo sapiens OX=9606 GN=EIF2S3B PE=2 SV=2 9.75 3243.4 - 1.26E+06 - - - -0.185 - 1.324 0.078 - 159.4 1 2 0 -0.0002 8 0 0 0 2.24E+08 2.29E+08 - - - 0.4635 0.9983 221125_WJC_METTL3_EV_vs_WT_F01.15807.15807.2 0.0462 14-Jul R.LMGLEALK[136.11].S "sp|P48643|TCPE_HUMAN,tr|D6RIZ7|D6RIZ7_HUMAN,tr|E7ENZ3|E7ENZ3_HUMAN,tr|H0Y914|H0Y914_HUMAN" 4 881.5136 0.53 4100 15807 2 881.513077 441.7641 T-complex protein 1 subunit epsilon OS=Homo sapiens OX=9606 GN=CCT5 PE=1 SV=1 6 3244.1 - 8.64E+07 - - - -0.5649 - 1.46 0.24 - 141.8 1 2 0 -0.0005 8 0 0 0 1.15E+09 2.16E+09 - - - 1.9548 0.9991 221125_WJC_METTL3_EV_vs_WT_F01.15811.15811.2 0.384 12-Jul K.LMFEELR.N sp|Q9Y3I0|RTCB_HUMAN 1 936.4739 1.05 4103 15811 2 936.474255 469.2442 RNA-splicing ligase RtcB homolog OS=Homo sapiens OX=9606 GN=RTCB PE=1 SV=1 4.53 3244.5 - 623771 - - - 0.3908 - 1.485 0.303 - 163.8 1 2 0 0.0004 7 0 0 0 1.54E+08 1.47E+08 - - - 2.5317 0.9998 221125_WJC_METTL3_EV_vs_WT_F01.15821.15821.2 6.55E-05 16-Sep R.IGFGSFVEK.T "sp|P05556|ITB1_HUMAN,sp|P18564|ITB6_HUMAN,tr|A0A7I2V2F9|A0A7I2V2F9_HUMAN,tr|A0A087WXP3|A0A087WXP3_HUMAN,tr|A0A7I2V5T3|A0A7I2V5T3_HUMAN,tr|H7C4K3|H7C4K3_HUMAN,tr|E7EUI6|E7EUI6_HUMAN,tr|E9PEE8|E9PEE8_HUMAN,tr|A0A7I2V5Z8|A0A7I2V5Z8_HUMAN,tr|A0A7I2V348|A0A7I2V348_HUMAN,tr|C9JPK5|C9JPK5_HUMAN" 11 982.5124 1.05 4109 15821 2 982.511924 492.2635 Integrin beta-1 OS=Homo sapiens OX=9606 GN=ITGB1 PE=1 SV=2 6 3245.8 - 956472 - - - -0.4672 - 1.795 0.473 - 149.1 1 2 0 -0.0005 9 0 0 0 1.68E+07 1.60E+07 - - - 4.2269 0.9998 221125_WJC_METTL3_EV_vs_WT_F01.15822.15822.2 1.42E-05 16-Oct R.FDDPLLGPR[166.11].R "sp|Q9P2J5|SYLC_HUMAN,tr|A0A6I8PIV1|A0A6I8PIV1_HUMAN,tr|A0A6I8PRS0|A0A6I8PRS0_HUMAN,tr|A0A6I8PIT3|A0A6I8PIT3_HUMAN,tr|A0A6I8PLB3|A0A6I8PLB3_HUMAN,tr|A0A6I8PS05|A0A6I8PS05_HUMAN,tr|B4DER1|B4DER1_HUMAN,tr|A0A6I8PL42|A0A6I8PL42_HUMAN" 8 1038.5374 1.08 4110 15822 2 1038.535413 520.276 "Leucine--tRNA ligase, cytoplasmic OS=Homo sapiens OX=9606 GN=LARS1 PE=1 SV=2" 4.21 3245.9 - 2.76E+06 - - - -1.8796 - 2.036 0.509 - 348.4 1 2 0 -0.002 9 0 0 0 8.91E+07 8.23E+07 - - - 4.8568 0.9958 221125_WJC_METTL3_EV_vs_WT_F01.15824.15824.2 0.239 12-Jun K.LWVLETK.E "sp|Q15061|WDR43_HUMAN,tr|C9JEE7|C9JEE7_HUMAN,tr|C9IZK7|C9IZK7_HUMAN" 3 887.5117 0.99 4112 15824 2 887.511106 444.7631 WD repeat-containing protein 43 OS=Homo sapiens OX=9606 GN=WDR43 PE=1 SV=3 6 3246.1 - 655203 - - - -0.6175 - 1.23 0.231 - 96.9 2 2 0 -0.0005 7 0 0 0 4.95E+07 4.98E+07 - - - 1.2685 0.9955 221125_WJC_METTL3_EV_vs_WT_F01.15827.15827.2 0.53 12-Jun R.IFVMIPK[136.11].S sp|Q8IUH3|RBM45_HUMAN 1 854.5179 1.97 4115 15827 2 854.517829 428.2662 RNA-binding protein 45 OS=Homo sapiens OX=9606 GN=RBM45 PE=1 SV=1 8.75 3246.4 - 455602 - - - -0.1205 - 1.165 0.223 - 97.1 1 2 0 -0.0001 7 0 0 0 3.37E+07 1.71E+07 - - - 1.172 0.9997 221125_WJC_METTL3_EV_vs_WT_F01.15836.15836.2 0.111 16-Aug K.IYPVGYFTK.E "sp|Q15517|CDSN_HUMAN,tr|G8JLG2|G8JLG2_HUMAN,tr|Q2L6G8|Q2L6G8_HUMAN" 3 1086.575 1173.58 4122 15836 2 1086.575286 544.2948 Corneodesmosin OS=Homo sapiens OX=9606 GN=CDSN PE=1 SV=3 8.5 3247.5 - 907151 - - - 0.2789 - 1.494 0.447 - 196.7 1 2 0 0.0003 9 0 0 0 2.75E+08 2.34E+05 - - - 3.5039 0.9869 221125_WJC_METTL3_EV_vs_WT_F01.15839.15839.2 3.44 14-Jul K.ALLPVLAK.R "sp|O75127|PTCD1_HUMAN,tr|G3V325|G3V325_HUMAN" 2 823.5531 0.88 4125 15839 2 823.553479 412.7838 "Pentatricopeptide repeat-containing protein 1, mitochondrial OS=Homo sapiens OX=9606 GN=PTCD1 PE=1 SV=2" 8.8 3247.9 - 328699 - - - 0.4298 - 1.312 0.113 - 119.5 3 2 0 0.0004 8 0 0 0 6.88E+06 7.87E+06 - - - 0.4814 0.9938 221125_WJC_METTL3_EV_vs_WT_F01.15841.15841.2 0.000231 18-Sep K.VNDVLIVPYR[166.11].K sp|Q14966|ZN638_HUMAN 1 1196.6793 1.69 4127 15841 2 1196.673348 599.3469 Zinc finger protein 638 OS=Homo sapiens OX=9606 GN=ZNF638 PE=1 SV=2 5.81 3248.1 - 150413 - - - -4.9562 - 1.742 0.389 - 297.9 1 2 0 -0.0059 10 0 0 0 5.40E+06 3.19E+06 - - - 3.4616 0.9999 221125_WJC_METTL3_EV_vs_WT_F01.15843.15843.2 0.000229 18-Oct K.FAAQELIEVK[136.11].R "sp|Q86U44|MTA70_HUMAN,tr|F5H6D8|F5H6D8_HUMAN,tr|H0YFV6|H0YFV6_HUMAN,tr|B4DTN4|B4DTN4_HUMAN" 4 1154.6427 0.02 4128 15843 2 1154.642871 578.3286 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 4.53 3248.3 - 4.18E+07 - - - 0.1697 - 2.079 0.466 - 267.4 1 2 0 0.0002 10 0 0 0 2.65E+07 1.12E+09 - - - 4.5257 0.9992 221125_WJC_METTL3_EV_vs_WT_F01.15845.15845.2 0.245 12-Aug K.LMFEELR[166.11].N sp|Q9Y3I0|RTCB_HUMAN 1 946.4822 1.24 4129 15845 2 946.482191 474.2484 RNA-splicing ligase RtcB homolog OS=Homo sapiens OX=9606 GN=RTCB PE=1 SV=1 4.53 3248.6 - 3.66E+06 - - - 0.0338 - 1.551 0.289 - 249.3 1 2 0 0 7 0 0 0 1.84E+08 1.49E+08 - - - 2.5662 0.9873 221125_WJC_METTL3_EV_vs_WT_F01.15846.15846.2 2.55 12-Jun K.FVSFLGR[166.11].T "sp|P52292|IMA1_HUMAN,tr|J3QLL0|J3QLL0_HUMAN,tr|J3KS65|J3KS65_HUMAN,tr|A0A7I2V3Z3|A0A7I2V3Z3_HUMAN,tr|A0A7I2YQE1|A0A7I2YQE1_HUMAN,tr|A0A7I2V487|A0A7I2V487_HUMAN,tr|A0A7I2V351|A0A7I2V351_HUMAN" 7 834.4627 1.14 4130 15846 2 834.462614 418.2386 Importin subunit alpha-1 OS=Homo sapiens OX=9606 GN=KPNA2 PE=1 SV=1 9.75 3248.6 - 1.48E+06 - - - -0.1558 - 1.149 0.132 - 102.9 1 2 0 -0.0001 7 0 0 0 4.94E+08 4.34E+08 - - - 0.456 0.9852 221125_WJC_METTL3_EV_vs_WT_F01.15847.15847.2 0.00173 14-Jul R.VVDLMAHM.A "sp|P04406|G3P_HUMAN,tr|E7EUT5|E7EUT5_HUMAN" 2 914.4354 - 4131 15847 2 914.435217 458.225 Glyceraldehyde-3-phosphate dehydrogenase OS=Homo sapiens OX=9606 GN=GAPDH PE=1 SV=3 5.08 3248.7 - 3.26E+06 - - - -0.1947 - 1.489 0.48 - 137.7 1 1 0 -0.0002 8 0 0 0 - - - - - 3.7869 0.9659 221125_WJC_METTL3_EV_vs_WT_F01.15848.15848.2 0.299 12-Jun K.FVSFLGR.T "sp|P52292|IMA1_HUMAN,tr|J3QLL0|J3QLL0_HUMAN,tr|J3KS65|J3KS65_HUMAN,tr|A0A7I2V3Z3|A0A7I2V3Z3_HUMAN,tr|A0A7I2YQE1|A0A7I2YQE1_HUMAN,tr|A0A7I2V487|A0A7I2V487_HUMAN,tr|A0A7I2V351|A0A7I2V351_HUMAN" 7 824.4545 1.13 4132 15848 2 824.454509 413.2345 Importin subunit alpha-1 OS=Homo sapiens OX=9606 GN=KPNA2 PE=1 SV=1 9.75 3248.8 - 897449 - - - 0.0425 - 1.288 0.014 - 109.9 2 2 0 0 7 0 0 0 4.90E+08 4.33E+08 - - - -0.1881 0.9084 221125_WJC_METTL3_EV_vs_WT_F01.15852.15852.2 0.629 12-May K.LWYTLDR[166.11].A sp|P00387|NB5R3_HUMAN 1 975.5053 1.31 4134 15852 2 975.5029 488.7599 NADH-cytochrome b5 reductase 3 OS=Homo sapiens OX=9606 GN=CYB5R3 PE=1 SV=3 5.84 3249.3 - 366794 - - - -2.4982 - 1.13 0.077 - 66.6 2 2 0 -0.0024 7 0 0 0 5.11E+07 3.90E+07 - - - -0.1383 0.9993 221125_WJC_METTL3_EV_vs_WT_F01.15854.15854.2 0.00114 16-Aug R.SAVYPLLYR[166.11].D "sp|Q9Y618|NCOR2_HUMAN,tr|C9J7T7|C9J7T7_HUMAN,tr|C9JE98|C9JE98_HUMAN,tr|H7C184|H7C184_HUMAN,tr|C9J0Q5|C9J0Q5_HUMAN,tr|A0A384DVL6|A0A384DVL6_HUMAN" 6 1090.6051 1.84 4136 15854 2 1090.607116 546.3098 Nuclear receptor corepressor 2 OS=Homo sapiens OX=9606 GN=NCOR2 PE=1 SV=3 8.31 3249.6 - 527297 - - - 1.8934 - 1.725 0.379 - 274.4 1 2 0 0.0021 9 0 0 0 6.70E+07 3.65E+07 - - - 3.417 0.9997 221125_WJC_METTL3_EV_vs_WT_F01.15859.15859.2 0.0032 20-Oct K.ILITTVPPNLR.K "sp|Q12905|ILF2_HUMAN,tr|B4DY09|B4DY09_HUMAN" 2 1235.7602 1.12 4140 15859 2 1235.76005 618.8874 Interleukin enhancer-binding factor 2 OS=Homo sapiens OX=9606 GN=ILF2 PE=1 SV=2 9.75 3250.2 - 2.67E+06 - - - -0.0874 - 2.053 0.372 - 324.4 1 2 0 -0.0001 11 0 0 0 1.27E+08 1.13E+08 - - - 3.7344 0.9998 221125_WJC_METTL3_EV_vs_WT_F01.15860.15860.2 0.0445 20-Oct K.ILITTVPPNLR[166.11].K "sp|Q12905|ILF2_HUMAN,tr|B4DY09|B4DY09_HUMAN" 2 1245.7684 1.24 4141 15860 2 1245.76841 623.8915 Interleukin enhancer-binding factor 2 OS=Homo sapiens OX=9606 GN=ILF2 PE=1 SV=2 9.75 3250.3 - 2.17E+06 - - - -0.0144 - 1.946 0.439 - 323.1 1 2 0 0 11 0 0 0 6.29E+07 5.06E+07 - - - 4.0845 0.9997 221125_WJC_METTL3_EV_vs_WT_F01.15861.15861.2 0.0237 14-Sep K.VTNLLMLK[136.11].G "sp|O95758|PTBP3_HUMAN,sp|P26599|PTBP1_HUMAN,sp|Q9UKA9|PTBP2_HUMAN,tr|A0A6Q8PEX4|A0A6Q8PEX4_HUMAN,tr|B4DI28|B4DI28_HUMAN,tr|A0A0U1RRM4|A0A0U1RRM4_HUMAN,tr|A0A6Q8PEZ3|A0A6Q8PEZ3_HUMAN,tr|A6NLN1|A6NLN1_HUMAN,tr|K7EKJ7|K7EKJ7_HUMAN,tr|X6R242|X6R242_HUMAN,tr|A0A6Q8PH43|A0A6Q8PH43_HUMAN,tr|K7ELW5|K7ELW5_HUMAN,tr|A0A7I2RVZ4|A0A7I2RVZ4_HUMAN,tr|K7ES59|K7ES59_HUMAN,tr|A0A6Q8PFE6|A0A6Q8PFE6_HUMAN,tr|A0A6Q8PFC0|A0A6Q8PFC0_HUMAN,tr|A0A7I2V4H6|A0A7I2V4H6_HUMAN,tr|A0A7I2V621|A0A7I2V621_HUMAN" 18 938.5714 0.95 4142 15861 2 938.571237 470.293 Polypyrimidine tract-binding protein 3 OS=Homo sapiens OX=9606 GN=PTBP3 PE=1 SV=2 8.72 3250.3 - 1.17E+07 - - - -0.1992 - 1.862 0.366 - 264.4 1 2 0 -0.0002 8 0 0 0 1.66E+09 1.74E+09 - - - 3.6191 0.9774 221125_WJC_METTL3_EV_vs_WT_F01.15863.15863.2 0.113 12-Jun K.LWYTLDR[166.11].A sp|P00387|NB5R3_HUMAN 1 975.5053 1.31 4144 15863 2 975.502076 488.7599 NADH-cytochrome b5 reductase 3 OS=Homo sapiens OX=9606 GN=CYB5R3 PE=1 SV=3 5.84 3250.5 - 397094 - - - -3.3429 - 1.356 0.189 - 101 2 2 0 -0.0033 7 0 0 0 5.11E+07 3.90E+07 - - - 1.2664 0.9902 221125_WJC_METTL3_EV_vs_WT_F01.15867.15867.2 0.214 14-Jul K.SIILEGFK.S sp|O95347|SMC2_HUMAN 1 905.5222 1.12 4146 15867 2 905.519772 453.7684 Structural maintenance of chromosomes protein 2 OS=Homo sapiens OX=9606 GN=SMC2 PE=1 SV=2 5.72 3251 - 405752 - - - -2.7023 - 1.243 0.25 - 157.3 1 2 0 -0.0024 8 0 0 0 6.41E+07 5.71E+07 - - - 1.5428 0.9297 221125_WJC_METTL3_EV_vs_WT_F01.15875.15875.2 0.324 18-Sep L.RPHGVLDNTR.V sp|Q68EN5|K895L_HUMAN 1 1163.616 3.03 4151 15875 2 1163.617385 582.8153 Uncharacterized protein KIAA0895-like OS=Homo sapiens OX=9606 GN=KIAA0895L PE=1 SV=1 9.61 3252 - 625958 - - - 1.2306 - 1.455 0.329 - 210.6 1 1 0 0.0014 10 0 0 0 1.29E+07 4.26E+06 - - - 2.5173 0.9957 221125_WJC_METTL3_EV_vs_WT_F01.15877.15877.2 0.292 14-Jun R.EPLLTLVK[136.11].E sp|Q13200|PSMD2_HUMAN 1 919.5834 0.57 4152 15877 2 919.582769 460.799 26S proteasome non-ATPase regulatory subunit 2 OS=Homo sapiens OX=9606 GN=PSMD2 PE=1 SV=3 6.1 3252.2 - 2.53E+06 - - - -0.6525 - 1.442 0.151 - 119.1 1 2 0 -0.0006 8 0 0 0 4.17E+07 7.26E+07 - - - 1.26 1 221125_WJC_METTL3_EV_vs_WT_F01.15879.15879.2 1.69E-08 13/22 R.VFASELNAGIIK[136.11].T "sp|Q9P2J5|SYLC_HUMAN,tr|A0A6I8PIV1|A0A6I8PIV1_HUMAN,tr|A0A6I8PRS0|A0A6I8PRS0_HUMAN,tr|A0A6I8PLB8|A0A6I8PLB8_HUMAN,tr|A0A6I8PIT3|A0A6I8PIT3_HUMAN,tr|A0A6I8PLB3|A0A6I8PLB3_HUMAN,tr|A0A6I8PS05|A0A6I8PS05_HUMAN,tr|B4DER1|B4DER1_HUMAN,tr|A0A6I8PL42|A0A6I8PL42_HUMAN" 9 1268.722 0.96 4154 15879 2 1268.7196 635.3683 "Leucine--tRNA ligase, cytoplasmic OS=Homo sapiens OX=9606 GN=LARS1 PE=1 SV=2" 5.97 3252.5 - 246647 - - - -1.8822 - 2.59 0.609 - 485.9 1 2 0 -0.0024 12 0 0 0 3.26E+07 3.41E+07 - - - 6.0423 0.9993 221125_WJC_METTL3_EV_vs_WT_F01.15882.15882.2 0.0274 12-Jul R.LAADDFR.T "sp|Q04695|K1C17_HUMAN,sp|P13645|K1C10_HUMAN,sp|O76015|KRT38_HUMAN,sp|Q2M2I5|K1C24_HUMAN,sp|Q15323|K1H1_HUMAN,sp|P02533|K1C14_HUMAN,sp|P05783|K1C18_HUMAN,sp|P08727|K1C19_HUMAN,sp|P08779|K1C16_HUMAN,sp|Q7Z3Y7|K1C28_HUMAN,sp|Q14532|K1H2_HUMAN,sp|P19012|K1C15_HUMAN,sp|O76013|KRT36_HUMAN,sp|Q14525|KT33B_HUMAN,sp|Q92764|KRT35_HUMAN,sp|O76014|KRT37_HUMAN,sp|P13646|K1C13_HUMAN,tr|F8VZY9|F8VZY9_HUMAN,tr|K7EPJ9|K7EPJ9_HUMAN,tr|C9JM50|C9JM50_HUMAN,tr|A0A1B0GVI3|A0A1B0GVI3_HUMAN,tr|K7EMD9|K7EMD9_HUMAN,tr|F5GWP8|F5GWP8_HUMAN,tr|K7ERE3|K7ERE3_HUMAN,tr|C4AM86|C4AM86_HUMAN" 25 806.3923 45.04 4155 15882 2 806.392398 404.2034 "Keratin, type I cytoskeletal 17 OS=Homo sapiens OX=9606 GN=KRT17 PE=1 SV=2" 4.21 3252.9 - 822706 - - - 0.1625 - 1.689 0.272 - 171 1 2 0 0.0001 7 0 0 0 8.40E+07 1.87E+06 - - - 2.7107 0.9769 221125_WJC_METTL3_EV_vs_WT_F01.15883.15883.2 0.652 12-May K.LWYTLDR.A sp|P00387|NB5R3_HUMAN 1 965.4971 1.16 4156 15883 2 965.49544 483.7558 NADH-cytochrome b5 reductase 3 OS=Homo sapiens OX=9606 GN=CYB5R3 PE=1 SV=3 5.84 3253 - 858163 - - - -1.6851 - 1.206 0.125 - 85.2 2 2 0 -0.0016 7 0 0 0 5.11E+07 4.40E+07 - - - 0.4228 0.9997 221125_WJC_METTL3_EV_vs_WT_F01.15884.15884.2 0.00235 18-Nov K.LGLTEDQFIR.T "sp|P28340|DPOD1_HUMAN,tr|M0QZR8|M0QZR8_HUMAN,tr|A0A2R8Y7K6|A0A2R8Y7K6_HUMAN,tr|A0A2R8Y705|A0A2R8Y705_HUMAN,tr|M0R2B7|M0R2B7_HUMAN,tr|A0A087WYJ2|A0A087WYJ2_HUMAN" 6 1190.6295 0.66 4157 15884 2 1190.629823 596.322 DNA polymerase delta catalytic subunit OS=Homo sapiens OX=9606 GN=POLD1 PE=1 SV=2 4.37 3253.1 - 503274 - - - 0.2394 - 2.046 0.355 - 326.8 1 2 0 0.0003 10 0 0 0 1.13E+07 1.69E+07 - - - 3.6612 0.9021 221125_WJC_METTL3_EV_vs_WT_F01.15887.15887.2 0.254 14-Aug G.TVNVSLPR.F sp|Q9BZF2|OSBL7_HUMAN 1 884.508 265.83 4158 15887 2 884.506907 443.2613 Oxysterol-binding protein-related protein 7 OS=Homo sapiens OX=9606 GN=OSBPL7 PE=1 SV=1 9.41 3253.5 - 5.34E+06 - - - -1.1973 - 1.468 0.257 - 261.9 1 1 0 -0.0011 8 0 0 0 8.92E+09 3.36E+07 - - - 2.0967 0.9998 221125_WJC_METTL3_EV_vs_WT_F01.15890.15890.2 0.000693 20-Dec K.LLDSITVPVAR[166.11].A sp|O00203|AP3B1_HUMAN 1 1192.7055 0.67 4161 15890 2 1192.704073 597.36 AP-3 complex subunit beta-1 OS=Homo sapiens OX=9606 GN=AP3B1 PE=1 SV=3 5.84 3253.9 - 591069 - - - -1.1906 - 2.345 0.467 - 369.3 1 2 0 -0.0014 11 0 0 0 2.25E+07 3.34E+07 - - - 4.7954 0.9999 221125_WJC_METTL3_EV_vs_WT_F01.15891.15891.2 4.35E-06 22-Oct R.VFASELNAGIIK.T "sp|Q9P2J5|SYLC_HUMAN,tr|A0A6I8PIV1|A0A6I8PIV1_HUMAN,tr|A0A6I8PRS0|A0A6I8PRS0_HUMAN,tr|A0A6I8PLB8|A0A6I8PLB8_HUMAN,tr|A0A6I8PIT3|A0A6I8PIT3_HUMAN,tr|A0A6I8PLB3|A0A6I8PLB3_HUMAN,tr|A0A6I8PS05|A0A6I8PS05_HUMAN,tr|B4DER1|B4DER1_HUMAN,tr|A0A6I8PL42|A0A6I8PL42_HUMAN" 9 1260.7078 0.96 4162 15891 2 1260.707777 631.3612 "Leucine--tRNA ligase, cytoplasmic OS=Homo sapiens OX=9606 GN=LARS1 PE=1 SV=2" 5.97 3254 - 453477 - - - -0.0087 - 1.898 0.573 - 270.6 1 2 0 0 12 0 0 0 3.26E+07 3.41E+07 - - - 4.9592 0.9995 221125_WJC_METTL3_EV_vs_WT_F01.15892.15892.2 0.00371 16-Jul R.SLFVVVGDR.G "sp|Q9H0A0|NAT10_HUMAN,tr|E9PMU0|E9PMU0_HUMAN,tr|E9PJN6|E9PJN6_HUMAN" 3 990.5498 0.69 4163 15892 2 990.548061 496.2822 RNA cytidine acetyltransferase OS=Homo sapiens OX=9606 GN=NAT10 PE=1 SV=2 5.55 3254.1 - 349607 - - - -1.7869 - 1.817 0.402 - 172.3 1 2 0 -0.0018 9 0 0 0 2.58E+07 3.72E+07 - - - 3.7373 0.967 221125_WJC_METTL3_EV_vs_WT_F01.15896.15896.2 0.00513 20-Nov R.ATVVVGDLHPL.R "sp|Q9NSI2|SLX9_HUMAN,tr|C9JJU7|C9JJU7_HUMAN" 2 1119.6288 - 4165 15896 2 1119.628325 560.8217 Ribosome biogenesis protein SLX9 homolog OS=Homo sapiens OX=9606 GN=SLX9 PE=1 SV=2 5.08 3254.6 - 819442 - - - -0.4323 - 1.947 0.28 - 320.4 1 1 0 -0.0005 11 0 0 0 - - - - - 2.9114 0.9995 221125_WJC_METTL3_EV_vs_WT_F01.15897.15897.2 0.000392 16-Oct R.SPVYLTVLK.H "sp|P55786|PSA_HUMAN,tr|A0A7I2V3W8|A0A7I2V3W8_HUMAN,tr|A0A7I2V389|A0A7I2V389_HUMAN,tr|E9PLK3|E9PLK3_HUMAN" 4 1018.6063 0.76 4166 15897 2 1018.608127 510.3104 Puromycin-sensitive aminopeptidase OS=Homo sapiens OX=9606 GN=NPEPPS PE=1 SV=2 8.31 3254.7 - 630664 - - - 1.8103 - 1.927 0.389 - 304.7 1 2 0 0.0018 9 0 0 0 3.34E+07 4.43E+07 - - - 3.8113 0.9451 221125_WJC_METTL3_EV_vs_WT_F01.15898.15898.2 0.00209 12-Jul Q.AAILHLK[136.11].R "sp|Q68DA7|FMN1_HUMAN,sp|Q8NHP7|EXD1_HUMAN,tr|H0YM30|H0YM30_HUMAN,tr|A0A5F9ZHS8|A0A5F9ZHS8_HUMAN" 4 772.5051 0.7 4167 15898 2 772.503616 387.2598 Formin-1 OS=Homo sapiens OX=9606 GN=FMN1 PE=1 SV=3 8.8 3254.8 - 2.36E+06 - - - -1.8679 - 1.506 0.366 - 210.1 1 1 0 -0.0014 7 0 0 0 5.58E+07 7.96E+07 - - - 3.0412 0.9894 221125_WJC_METTL3_EV_vs_WT_F01.15899.15899.2 2.38 12-Aug K.LPLLLSR.M "sp|P49902|5NTC_HUMAN,sp|O95866|G6B_HUMAN,tr|A0A140T9L8|A0A140T9L8_HUMAN,tr|A0A6Q8PHB5|A0A6Q8PHB5_HUMAN,tr|A0A140T9V1|A0A140T9V1_HUMAN,tr|A0A6Q8PHP0|A0A6Q8PHP0_HUMAN,tr|B7ZLJ5|B7ZLJ5_HUMAN,tr|A0A0G2JJG8|A0A0G2JJG8_HUMAN,tr|F8WDG3|F8WDG3_HUMAN,tr|Q5JUV4|Q5JUV4_HUMAN" 10 810.5327 1.57 4168 15899 2 810.531068 406.2736 Cytosolic purine 5'-nucleotidase OS=Homo sapiens OX=9606 GN=NT5C2 PE=1 SV=1 9.75 3254.9 - 644328 - - - -2.0431 - 1.629 0.074 - 276.7 1 2 0 -0.0017 7 0 0 0 3.11E+07 1.98E+07 - - - 1.1332 0.9732 221125_WJC_METTL3_EV_vs_WT_F01.15901.15901.2 0.843 14-Jul K.LFELTVER.T sp|Q9H0V9|LMA2L_HUMAN 1 1005.5495 1.05 4170 15901 2 1005.547556 503.782 VIP36-like protein OS=Homo sapiens OX=9606 GN=LMAN2L PE=1 SV=1 4.53 3255.1 - 396710 - - - -1.9293 - 1.267 0.11 - 142.6 2 2 0 -0.0019 8 0 0 0 2.28E+07 2.16E+07 - - - 0.4321 0.9999 221125_WJC_METTL3_EV_vs_WT_F01.15907.15907.2 0.00225 20-Nov K.LLDSITVPVAR.A sp|O00203|AP3B1_HUMAN 1 1182.6972 0.67 4174 15907 2 1182.697191 592.3559 AP-3 complex subunit beta-1 OS=Homo sapiens OX=9606 GN=AP3B1 PE=1 SV=3 5.84 3255.9 - 824518 - - - -0.0271 - 2.362 0.487 - 389.4 1 2 0 0 11 0 0 0 2.25E+07 3.34E+07 - - - 4.9631 1 221125_WJC_METTL3_EV_vs_WT_F01.15917.15917.2 7.86E-08 14/32 K.GILFVGSGVSGGEEGAR[166.11].Y "sp|P52209|6PGD_HUMAN,tr|K7EMN2|K7EMN2_HUMAN,tr|K7EPF6|K7EPF6_HUMAN,tr|K7EM49|K7EM49_HUMAN" 4 1600.8085 0.01 4180 15917 2 1600.80556 801.4115 "6-phosphogluconate dehydrogenase, decarboxylating OS=Homo sapiens OX=9606 GN=PGD PE=1 SV=3" 4.53 3257.1 - 288083 - - - -1.8085 - 2.774 0.602 - 494.1 1 2 0 -0.0029 17 0 0 0 1.04E+05 8.09E+06 - - - 5.9949 0.9907 221125_WJC_METTL3_EV_vs_WT_F01.15920.15920.2 0.366 16-Jul R.IVLNGIDLK.A sp|O15294|OGT1_HUMAN 1 983.6015 1.49 4183 15920 2 983.600832 492.808 UDP-N-acetylglucosamine--peptide N-acetylglucosaminyltransferase 110 kDa subunit OS=Homo sapiens OX=9606 GN=OGT PE=1 SV=3 5.84 3257.4 - 487606 - - - -0.7117 - 1.192 0.159 - 97.5 1 2 0 -0.0007 9 0 0 0 2.03E+07 1.37E+07 - - - 0.7233 0.9995 221125_WJC_METTL3_EV_vs_WT_F01.15924.15924.2 0.00312 22-Oct K.LGALTAEEIALK.M sp|Q13601|KRR1_HUMAN 1 1227.7075 2 4185 15924 2 1227.704575 614.861 KRR1 small subunit processome component homolog OS=Homo sapiens OX=9606 GN=KRR1 PE=1 SV=4 4.53 3257.9 - 690615 - - - -2.345 - 2.206 0.426 - 270.3 1 2 0 -0.0029 12 0 0 0 7.74E+07 3.86E+07 - - - 4.2683 0.9998 221125_WJC_METTL3_EV_vs_WT_F01.15939.15939.2 0.00211 16-Sep K.FGLFTPGSR.L "sp|P36551|HEM6_HUMAN,tr|H0YA22|H0YA22_HUMAN" 2 980.508 1.21 4193 15939 2 980.507532 491.2613 "Oxygen-dependent coproporphyrinogen-III oxidase, mitochondrial OS=Homo sapiens OX=9606 GN=CPOX PE=1 SV=3" 9.75 3259.6 - 971304 - - - -0.4426 - 2.098 0.374 - 262 1 2 0 -0.0004 9 0 0 0 1.05E+08 8.62E+07 - - - 3.9469 0.9871 221125_WJC_METTL3_EV_vs_WT_F01.15944.15944.2 1.17 12-Jun R.FLWNQVR[166.11].S "sp|Q8IW35|CEP97_HUMAN,tr|E9PG22|E9PG22_HUMAN,tr|A0A0U1RR97|A0A0U1RR97_HUMAN" 3 971.5217 0.48 4195 15944 2 971.521859 486.7681 Centrosomal protein of 97 kDa OS=Homo sapiens OX=9606 GN=CEP97 PE=1 SV=1 9.75 3260.3 - 488483 - - - 0.209 - 1.189 0.118 - 118.8 1 2 0 0.0002 7 0 0 0 6.67E+06 1.38E+07 - - - 0.461 0.9999 221125_WJC_METTL3_EV_vs_WT_F01.15946.15946.2 6.08E-05 20-Nov R.VGASEAALFLK.K "sp|Q9UBC2|EP15R_HUMAN,tr|M0QX30|M0QX30_HUMAN,tr|K7EJR2|K7EJR2_HUMAN,tr|M0R1V5|M0R1V5_HUMAN,tr|M0R330|M0R330_HUMAN,tr|M0R165|M0R165_HUMAN" 6 1104.6179 1.52 4196 15946 2 1104.618504 553.3162 Epidermal growth factor receptor substrate 15-like 1 OS=Homo sapiens OX=9606 GN=EPS15L1 PE=1 SV=1 5.97 3260.6 - 847692 - - - 0.5377 - 2.359 0.502 - 338.2 1 2 0 0.0006 11 0 0 0 2.83E+07 1.86E+07 - - - 5.0703 0.9978 221125_WJC_METTL3_EV_vs_WT_F01.15948.15948.2 0.113 12-Jul R.SFDLLVK[136.11].N sp|Q9HB71|CYBP_HUMAN 1 828.4837 0.47 4197 15948 2 828.482966 415.2491 Calcyclin-binding protein OS=Homo sapiens OX=9606 GN=CACYBP PE=1 SV=2 5.55 3260.8 - 2.73E+06 - - - -0.8316 - 1.422 0.222 - 175.1 1 2 0 -0.0007 7 0 0 0 8.19E+07 1.74E+08 - - - 1.796 0.9996 221125_WJC_METTL3_EV_vs_WT_F01.15950.15950.2 0.00323 22-Sep K.LGALTAEEIALK[136.11].M sp|Q13601|KRR1_HUMAN 1 1235.7217 1.96 4199 15950 2 1235.720266 618.8681 KRR1 small subunit processome component homolog OS=Homo sapiens OX=9606 GN=KRR1 PE=1 SV=4 4.53 3261 - 1.47E+06 - - - -1.1232 - 1.982 0.358 - 205.7 1 2 0 -0.0014 12 0 0 0 7.55E+07 3.86E+07 - - - 3.4848 0.9995 221125_WJC_METTL3_EV_vs_WT_F01.15951.15951.2 7.50E-05 20-Oct R.VGASEAALFLK[136.11].K "sp|Q9UBC2|EP15R_HUMAN,tr|M0QX30|M0QX30_HUMAN,tr|K7EJR2|K7EJR2_HUMAN,tr|M0R1V5|M0R1V5_HUMAN,tr|M0R330|M0R330_HUMAN,tr|M0R165|M0R165_HUMAN" 6 1112.6321 1.52 4200 15951 2 1112.634618 557.3233 Epidermal growth factor receptor substrate 15-like 1 OS=Homo sapiens OX=9606 GN=EPS15L1 PE=1 SV=1 5.97 3261.1 - 761227 - - - 2.2541 - 2.156 0.43 - 348.5 1 2 0 0.0025 11 0 0 0 2.83E+07 1.87E+07 - - - 4.2945 0.9992 221125_WJC_METTL3_EV_vs_WT_F01.15952.15952.2 0.298 20-Sep R.IDALLAVDPPR.A sp|P50219|MNX1_HUMAN 1 1178.6659 1.99 4201 15952 2 1178.664826 590.3402 Motor neuron and pancreas homeobox protein 1 OS=Homo sapiens OX=9606 GN=MNX1 PE=1 SV=3 4.21 3261.3 - 899066 - - - -0.9307 - 2.124 0.225 - 267.6 1 2 0 -0.0011 11 0 0 0 2.17E+07 1.09E+07 - - - 2.7404 0.9981 221125_WJC_METTL3_EV_vs_WT_F01.15954.15954.2 0.043 14-Jun K.VTNLLMLK.G "sp|O95758|PTBP3_HUMAN,sp|P26599|PTBP1_HUMAN,sp|Q9UKA9|PTBP2_HUMAN,tr|A0A6Q8PEX4|A0A6Q8PEX4_HUMAN,tr|B4DI28|B4DI28_HUMAN,tr|A0A0U1RRM4|A0A0U1RRM4_HUMAN,tr|A0A6Q8PEZ3|A0A6Q8PEZ3_HUMAN,tr|A6NLN1|A6NLN1_HUMAN,tr|K7EKJ7|K7EKJ7_HUMAN,tr|X6R242|X6R242_HUMAN,tr|A0A6Q8PH43|A0A6Q8PH43_HUMAN,tr|K7ELW5|K7ELW5_HUMAN,tr|A0A7I2RVZ4|A0A7I2RVZ4_HUMAN,tr|K7ES59|K7ES59_HUMAN,tr|A0A6Q8PFE6|A0A6Q8PFE6_HUMAN,tr|A0A6Q8PFC0|A0A6Q8PFC0_HUMAN,tr|A0A7I2V4H6|A0A7I2V4H6_HUMAN,tr|A0A7I2V621|A0A7I2V621_HUMAN" 18 930.5572 0.96 4202 15954 2 930.55699 466.2859 Polypyrimidine tract-binding protein 3 OS=Homo sapiens OX=9606 GN=PTBP3 PE=1 SV=2 8.72 3261.5 - 1.37E+07 - - - -0.2515 - 1.573 0.192 - 104.6 1 2 0 -0.0002 8 0 0 0 1.67E+09 1.74E+09 - - - 1.8252 0.9997 221125_WJC_METTL3_EV_vs_WT_F01.15958.15958.2 0.000292 20-Oct R.LLTGVEYVVGR.K "sp|O60934|NBN_HUMAN,tr|E2QRP0|E2QRP0_HUMAN,tr|E5RGU1|E5RGU1_HUMAN" 3 1204.6816 1.46 4205 15958 2 1204.682378 603.3481 Nibrin OS=Homo sapiens OX=9606 GN=NBN PE=1 SV=1 6 3261.9 - 938822 - - - 0.6682 - 2.024 0.37 - 234.5 1 2 0 0.0008 11 0 0 0 2.74E+07 1.87E+07 - - - 3.681 0.9997 221125_WJC_METTL3_EV_vs_WT_F01.15960.15960.2 0.000413 24-Sep R.ILGPAESDEFLAR[166.11].V "sp|Q5T4S7|UBR4_HUMAN,tr|A0A0A0MSW0|A0A0A0MSW0_HUMAN" 2 1426.7332 0.89 4207 15960 2 1426.734352 714.3739 E3 ubiquitin-protein ligase UBR4 OS=Homo sapiens OX=9606 GN=UBR4 PE=1 SV=1 4.14 3262.2 - 123784 - - - 0.832 - 1.783 0.463 - 128.1 1 2 0 0.0012 13 0 0 0 2.37E+06 2.65E+06 - - - 3.9446 0.9996 221125_WJC_METTL3_EV_vs_WT_F01.15962.15962.2 0.16 16-Sep K.FGLFTPGSR[166.11].L "sp|P36551|HEM6_HUMAN,tr|H0YA22|H0YA22_HUMAN" 2 990.5162 1.21 4208 15962 2 990.515685 496.2654 "Oxygen-dependent coproporphyrinogen-III oxidase, mitochondrial OS=Homo sapiens OX=9606 GN=CPOX PE=1 SV=3" 9.75 3262.4 - 2.91E+06 - - - -0.5563 - 1.993 0.293 - 284 1 2 0 -0.0006 9 0 0 0 1.04E+08 8.62E+07 - - - 3.2001 0.9985 221125_WJC_METTL3_EV_vs_WT_F01.15964.15964.2 0.0496 12-Aug R.SFDLLVK.N sp|Q9HB71|CYBP_HUMAN 1 820.4695 0.47 4209 15964 2 820.469334 411.242 Calcyclin-binding protein OS=Homo sapiens OX=9606 GN=CACYBP PE=1 SV=2 5.55 3262.6 - 2.78E+06 - - - -0.1475 - 1.384 0.261 - 232.8 1 2 0 -0.0001 7 0 0 0 8.19E+07 1.75E+08 - - - 1.9984 0.9777 221125_WJC_METTL3_EV_vs_WT_F01.15966.15966.2 0.00038 18-Jul L.VLPVVFETEK.L sp|Q9NS69|TOM22_HUMAN 1 1159.6489 1.47 4211 15966 2 1159.650052 580.8317 Mitochondrial import receptor subunit TOM22 homolog OS=Homo sapiens OX=9606 GN=TOMM22 PE=1 SV=3 4.53 3262.8 - 1.17E+06 - - - 1.0141 - 1.578 0.45 - 138 1 1 0 0.0012 10 0 0 0 3.32E+07 2.26E+07 - - - 3.6376 0.913 221125_WJC_METTL3_EV_vs_WT_F01.15967.15967.2 0.899 16-Jun K.TVIGSVLLR.E sp|O00203|AP3B1_HUMAN 1 956.6019 1.28 4212 15967 2 956.604809 479.3082 AP-3 complex subunit beta-1 OS=Homo sapiens OX=9606 GN=AP3B1 PE=1 SV=3 9.41 3262.9 - 282745 - - - 3.0765 - 1.074 0.145 - 112.6 2 2 0 0.0029 9 0 0 0 2.86E+07 2.24E+07 - - - 0.1831 0.9713 221125_WJC_METTL3_EV_vs_WT_F01.15971.15971.2 0.814 12-Jul K.YYTLFGR[166.11].S sp|P07814|SYEP_HUMAN 1 928.4682 0.76 4214 15971 2 928.467978 465.2414 Bifunctional glutamate\proline--tRNA ligase OS=Homo sapiens OX=9606 GN=EPRS1 PE=1 SV=5 8.59 3263.5 - 6.19E+06 - - - -0.2639 - 1.124 0.069 - 143 1 2 0 -0.0002 7 0 0 0 9.58E+07 1.26E+08 - - - -0.0791 0.9998 221125_WJC_METTL3_EV_vs_WT_F01.15981.15981.2 9.29E-05 18-Sep K.AAPEMVSLLK[136.11].R "sp|Q92947|GCDH_HUMAN,tr|K7ESA6|K7ESA6_HUMAN,tr|K7EQ99|K7EQ99_HUMAN" 3 1065.5984 0.86 4222 15981 2 1065.597822 533.8065 "Glutaryl-CoA dehydrogenase, mitochondrial OS=Homo sapiens OX=9606 GN=GCDH PE=1 SV=1" 6.05 3264.6 - 1.25E+06 - - - -0.5114 - 1.904 0.492 - 348.2 1 2 0 -0.0005 10 0 0 0 6.50E+07 7.60E+07 - - - 4.4722 0.9923 221125_WJC_METTL3_EV_vs_WT_F01.15982.15982.2 0.733 14-Jun K.VIILSLDR.S "sp|P78344|IF4G2_HUMAN,tr|E9PKF8|E9PKF8_HUMAN,tr|H0Y3P2|H0Y3P2_HUMAN,tr|D3DQV9|D3DQV9_HUMAN" 4 927.5753 2.18 4223 15982 2 927.575276 464.7949 Eukaryotic translation initiation factor 4 gamma 2 OS=Homo sapiens OX=9606 GN=EIF4G2 PE=1 SV=1 5.81 3264.6 - 6.29E+06 - - - -0.0442 - 1.277 0.138 - 159.2 1 2 0 0 8 0 0 0 5.98E+08 2.74E+08 - - - 0.7977 0.9995 221125_WJC_METTL3_EV_vs_WT_F01.15985.15985.2 0.00885 16-Oct K.NAIVVLIPK[136.11].Y "sp|Q9Y2L1|RRP44_HUMAN,tr|G3V1J5|G3V1J5_HUMAN" 2 973.6416 1.51 4226 15985 2 973.641902 487.8281 Exosome complex exonuclease RRP44 OS=Homo sapiens OX=9606 GN=DIS3 PE=1 SV=2 8.75 3264.9 - 541858 - - - 0.3584 - 1.541 0.389 - 272.3 1 2 0 0.0003 9 0 0 0 1.84E+08 1.22E+08 - - - 3.1651 0.8433 221125_WJC_METTL3_EV_vs_WT_F01.15990.15990.2 0.386 20-Jul K.VLEVPPVVYSR[166.11].Q "sp|O00154|BACH_HUMAN,tr|K7EKP8|K7EKP8_HUMAN" 2 1266.7211 0.01 4231 15990 2 1267.72364 634.3678 Cytosolic acyl coenzyme A thioester hydrolase OS=Homo sapiens OX=9606 GN=ACOT7 PE=1 SV=3 5.97 3265.6 - 129505 - - - 791.411 - 1.484 0.194 - 183.5 1 2 0 1.0025 11 0 0 0 3.37E+05 2.39E+07 - - - 1.227 0.9993 221125_WJC_METTL3_EV_vs_WT_F01.15993.15993.2 0.0259 14-Aug K.VIILSLDR[166.11].S "sp|P78344|IF4G2_HUMAN,tr|E9PKF8|E9PKF8_HUMAN,tr|H0Y3P2|H0Y3P2_HUMAN,tr|D3DQV9|D3DQV9_HUMAN" 4 937.5836 2.18 4232 15993 2 937.583103 469.7991 Eukaryotic translation initiation factor 4 gamma 2 OS=Homo sapiens OX=9606 GN=EIF4G2 PE=1 SV=1 5.81 3266 - 5.72E+06 - - - -0.5162 - 1.69 0.285 - 279.5 1 2 0 -0.0005 8 0 0 0 5.98E+08 2.74E+08 - - - 2.7284 0.9534 221125_WJC_METTL3_EV_vs_WT_F01.15994.15994.2 2.45 14-Jul K.GITLSVRP.- tr|A0A075B6Z2|A0A075B6Z2_HUMAN 1 841.5022 197.75 4233 15994 2 841.501239 421.7584 T cell receptor alpha joining 56 (Fragment) OS=Homo sapiens OX=9606 GN=TRAJ56 PE=4 SV=1 9.75 3266.1 - 2.03E+06 - - - -1.085 - 1.332 0.007 - 178.3 3 2 0 -0.0009 8 0 0 0 1.76E+08 8.89E+05 - - - -0.2561 0.9998 221125_WJC_METTL3_EV_vs_WT_F01.15997.15997.2 0.000536 18-Sep R.VILDLTPNYR[166.11].G "sp|P08195|4F2_HUMAN,tr|A0A7P0TAN7|A0A7P0TAN7_HUMAN,tr|J3KPF3|J3KPF3_HUMAN,tr|F5H056|F5H056_HUMAN,tr|H0YH36|H0YH36_HUMAN,tr|F5GZI0|F5GZI0_HUMAN,tr|A0A7P0T8U7|A0A7P0T8U7_HUMAN,tr|A0A7P0T9F7|A0A7P0T9F7_HUMAN,tr|A0A7P0TBF8|A0A7P0TBF8_HUMAN,tr|A0A7P0T8F1|A0A7P0T8F1_HUMAN,tr|A0A7P0Z4A0|A0A7P0Z4A0_HUMAN,tr|F5GZS6|F5GZS6_HUMAN,tr|A0A7P0Z4P5|A0A7P0Z4P5_HUMAN,tr|A0A7P0TAS6|A0A7P0TAS6_HUMAN" 14 1212.6742 1.49 4236 15997 2 1212.674054 607.3444 4F2 cell-surface antigen heavy chain OS=Homo sapiens OX=9606 GN=SLC3A2 PE=1 SV=3 5.81 3266.3 - 709383 - - - -0.1146 - 1.966 0.475 - 296.6 1 2 0 -0.0001 10 0 0 0 3.29E+07 2.20E+07 - - - 4.4362 0.992 221125_WJC_METTL3_EV_vs_WT_F01.15998.15998.2 0.781 20-Oct R.IDALLAVDPPR[166.11].A sp|P50219|MNX1_HUMAN 1 1188.6742 1.72 4237 15998 2 1188.677244 595.3444 Motor neuron and pancreas homeobox protein 1 OS=Homo sapiens OX=9606 GN=MNX1 PE=1 SV=3 4.21 3266.4 - 423800 - - - 2.5667 - 1.999 0.101 - 330.3 1 2 0 0.0031 11 0 0 0 5.45E+07 3.16E+07 - - - 1.6598 0.9575 221125_WJC_METTL3_EV_vs_WT_F01.16004.16004.2 1.75 14-Jul K.GYGFGLIK[136.11].L "sp|P21796|VDAC1_HUMAN,tr|C9JI87|C9JI87_HUMAN" 2 861.484 1.16 4241 16004 2 861.482352 431.7493 Voltage-dependent anion-selective channel protein 1 OS=Homo sapiens OX=9606 GN=VDAC1 PE=1 SV=2 8.59 3267.1 - 1.21E+06 - - - -1.9014 - 1.103 0.123 - 113.4 2 2 0 -0.0016 8 0 0 0 6.44E+08 5.54E+08 - - - 0.1102 0.9988 221125_WJC_METTL3_EV_vs_WT_F01.16006.16006.2 0.00589 16-Sep K.GLIDYETFK.E sp|P15924|DESP_HUMAN 1 1084.5441 7.31 4243 16006 2 1084.546795 543.2793 Desmoplakin OS=Homo sapiens OX=9606 GN=DSP PE=1 SV=3 4.37 3267.4 - 509101 - - - 2.5061 - 1.734 0.371 - 186.5 1 2 0 0.0027 9 0 0 0 7.53E+07 1.03E+07 - - - 3.3728 0.9996 221125_WJC_METTL3_EV_vs_WT_F01.16011.16011.2 0.0107 18-Jul R.VILDLTPNYR.G "sp|P08195|4F2_HUMAN,tr|A0A7P0TAN7|A0A7P0TAN7_HUMAN,tr|J3KPF3|J3KPF3_HUMAN,tr|F5H056|F5H056_HUMAN,tr|H0YH36|H0YH36_HUMAN,tr|F5GZI0|F5GZI0_HUMAN,tr|A0A7P0T8U7|A0A7P0T8U7_HUMAN,tr|A0A7P0T9F7|A0A7P0T9F7_HUMAN,tr|A0A7P0TBF8|A0A7P0TBF8_HUMAN,tr|A0A7P0T8F1|A0A7P0T8F1_HUMAN,tr|A0A7P0Z4A0|A0A7P0Z4A0_HUMAN,tr|F5GZS6|F5GZS6_HUMAN,tr|A0A7P0Z4P5|A0A7P0Z4P5_HUMAN,tr|A0A7P0TAS6|A0A7P0TAS6_HUMAN" 14 1202.6659 1.49 4247 16011 2 1202.665264 602.3402 4F2 cell-surface antigen heavy chain OS=Homo sapiens OX=9606 GN=SLC3A2 PE=1 SV=3 5.81 3268 - 985183 - - - -0.5479 - 1.651 0.374 - 163.4 1 2 0 -0.0007 10 0 0 0 3.41E+07 2.29E+07 - - - 3.2027 0.895 221125_WJC_METTL3_EV_vs_WT_F01.16012.16012.2 0.00178 16-Sep M.FEEVPIVIK.N "sp|O15372|EIF3H_HUMAN,tr|B3KS98|B3KS98_HUMAN,tr|A0A087WZK9|A0A087WZK9_HUMAN,tr|E5RGU4|E5RGU4_HUMAN,tr|E5RJT0|E5RJT0_HUMAN" 5 1072.6168 3.2 4248 16012 2 1072.620655 537.3157 Eukaryotic translation initiation factor 3 subunit H OS=Homo sapiens OX=9606 GN=EIF3H PE=1 SV=1 4.53 3268.1 - 596715 - - - 3.5493 - 1.66 0.424 - 189.9 1 1 0 0.0038 9 0 0 0 1.11E+07 3.47E+06 - - - 3.6377 0.9953 221125_WJC_METTL3_EV_vs_WT_F01.16018.16018.2 4.54 14-Jul R.ALDIPLVK[136.11].N "sp|Q6P2Q9|PRP8_HUMAN,tr|I3L0J9|I3L0J9_HUMAN" 2 875.5572 1.16 4251 16018 2 875.557228 438.7859 Pre-mRNA-processing-splicing factor 8 OS=Homo sapiens OX=9606 GN=PRPF8 PE=1 SV=2 5.88 3268.9 - 1.70E+06 - - - 0.0845 - 1.33 0.169 - 153.7 1 2 0 0.0001 8 0 0 0 1.55E+08 1.34E+08 - - - 1.1493 0.9995 221125_WJC_METTL3_EV_vs_WT_F01.16019.16019.2 0.000133 22-Jul R.MPGSVIPPPLVR[166.11].G sp|Q86YP4|P66A_HUMAN 1 1271.7299 1.42 4252 16019 2 1271.731971 636.8722 Transcriptional repressor p66-alpha OS=Homo sapiens OX=9606 GN=GATAD2A PE=1 SV=1 9.5 3269 - 188780 - - - 1.6018 - 1.569 0.464 - 121.9 1 2 0 0.002 12 0 0 0 2.37E+07 1.67E+07 - - - 3.6526 0.9964 221125_WJC_METTL3_EV_vs_WT_F01.16025.16025.2 0.291 14-Sep K.LLELLPGK[136.11].V "sp|Q8N684|CPSF7_HUMAN,tr|F5H047|F5H047_HUMAN,tr|F5H669|F5H669_HUMAN,tr|F5H6M0|F5H6M0_HUMAN,tr|J3QT54|J3QT54_HUMAN" 5 889.5728 1.45 4256 16025 2 889.571266 445.7937 Cleavage and polyadenylation specificity factor subunit 7 OS=Homo sapiens OX=9606 GN=CPSF7 PE=1 SV=1 6 3269.8 - 989576 - - - -1.73 - 1.407 0.233 - 220.9 1 2 0 -0.0015 8 0 0 0 1.38E+08 9.45E+07 - - - 1.7913 0.9998 221125_WJC_METTL3_EV_vs_WT_F01.16026.16026.2 0.0375 16-Oct K.NAIVVLIPK.Y "sp|Q9Y2L1|RRP44_HUMAN,tr|G3V1J5|G3V1J5_HUMAN" 2 965.6274 1.51 4257 16026 2 965.62724 483.821 Exosome complex exonuclease RRP44 OS=Homo sapiens OX=9606 GN=DIS3 PE=1 SV=2 8.75 3269.8 - 2.97E+06 - - - -0.117 - 1.898 0.392 - 413.7 1 2 0 -0.0001 9 0 0 0 1.84E+08 1.22E+08 - - - 3.7901 0.9343 221125_WJC_METTL3_EV_vs_WT_F01.16027.16027.2 0.919 18-Jun R.LAC[160.03]GVIGIAQ.- "sp|P00441|SODC_HUMAN,tr|H7BYH4|H7BYH4_HUMAN" 2 1000.5376 - 4258 16027 2 1000.54075 501.2761 Superoxide dismutase [Cu-Zn] OS=Homo sapiens OX=9606 GN=SOD1 PE=1 SV=2 5.52 3269.9 - 1.48E+06 - - - 3.1963 - 1.145 0.138 - 80.9 1 2 0 0.0032 10 0 0 0 - - - - - 0.4372 0.9426 221125_WJC_METTL3_EV_vs_WT_F01.16033.16033.2 0.474 12-Mar K.YYTLFGR.S sp|P07814|SYEP_HUMAN 1 918.46 0.67 4261 16033 2 918.459865 460.2373 Bifunctional glutamate\proline--tRNA ligase OS=Homo sapiens OX=9606 GN=EPRS1 PE=1 SV=5 8.59 3270.8 - 758816 - - - -0.0958 - 0.938 0.19 - 21.4 54 2 0 -0.0001 7 0 0 0 9.78E+07 1.45E+08 - - - -0.5324 0.9852 221125_WJC_METTL3_EV_vs_WT_F01.16035.16035.2 0.457 14-Jul K.GYGFGLIK.L "sp|P21796|VDAC1_HUMAN,tr|C9JI87|C9JI87_HUMAN" 2 853.4698 1.16 4262 16035 2 853.470005 427.7422 Voltage-dependent anion-selective channel protein 1 OS=Homo sapiens OX=9606 GN=VDAC1 PE=1 SV=2 8.59 3271 - 1.17E+07 - - - 0.2519 - 0.938 0.207 - 123.3 1 2 0 0.0002 8 0 0 0 6.44E+08 5.54E+08 - - - 0.3768 0.9816 221125_WJC_METTL3_EV_vs_WT_F01.16038.16038.2 0.0649 14-Aug R.LIAELLSR.A "sp|Q02040|AK17A_HUMAN,sp|A6NCM1|IQCAL_HUMAN,tr|X6RAJ1|X6RAJ1_HUMAN" 3 913.5597 1.76 4265 16038 2 913.564047 457.7871 A-kinase anchor protein 17A OS=Homo sapiens OX=9606 GN=AKAP17A PE=1 SV=2 6 3271.3 - 681468 - - - 4.7944 - 1.428 0.295 - 150.9 1 2 0 0.0044 8 0 0 0 2.94E+07 1.68E+07 - - - 2.293 0.9987 221125_WJC_METTL3_EV_vs_WT_F01.16044.16044.2 0.0173 16-Sep R.LTQEVLLLR[166.11].E "sp|Q5VU43|MYOME_HUMAN,tr|E9PQG4|E9PQG4_HUMAN,tr|A0A087WX83|A0A087WX83_HUMAN,tr|A0A075B749|A0A075B749_HUMAN" 4 1093.6735 2.36 4268 16044 2 1093.671053 547.844 Myomegalin OS=Homo sapiens OX=9606 GN=PDE4DIP PE=1 SV=3 6 3272.1 - 346613 - - - -2.2054 - 2.148 0.231 - 231.1 1 2 0 -0.0024 9 0 0 0 1.63E+07 6.90E+06 - - - 2.9583 0.9996 221125_WJC_METTL3_EV_vs_WT_F01.16050.16050.2 0.00054 20-Sep K.VLEVPPVVYSR.Q "sp|O00154|BACH_HUMAN,tr|K7EKP8|K7EKP8_HUMAN" 2 1256.7129 0.92 4271 16050 2 1256.710182 629.3637 Cytosolic acyl coenzyme A thioester hydrolase OS=Homo sapiens OX=9606 GN=ACOT7 PE=1 SV=3 5.97 3272.9 - 454656 - - - -2.1413 - 2.089 0.454 - 272.1 1 2 0 -0.0027 11 0 0 0 2.14E+07 2.34E+07 - - - 4.3863 0.9992 221125_WJC_METTL3_EV_vs_WT_F01.16054.16054.2 0.0205 16-Oct K.YIIEELNVR.K "sp|P41252|SYIC_HUMAN,tr|A0A804HL54|A0A804HL54_HUMAN,tr|A0A804HIV9|A0A804HIV9_HUMAN,tr|A0A804HJN6|A0A804HJN6_HUMAN,tr|A0A804HHW9|A0A804HHW9_HUMAN,tr|A0A0A0MSX9|A0A0A0MSX9_HUMAN,tr|J3KR24|J3KR24_HUMAN,tr|A0A804HJ36|A0A804HJ36_HUMAN" 8 1147.6237 0.86 4273 16054 2 1147.622462 574.8191 "Isoleucine--tRNA ligase, cytoplasmic OS=Homo sapiens OX=9606 GN=IARS1 PE=1 SV=2" 4.53 3273.4 - 865863 - - - -1.0997 - 1.588 0.328 - 371.2 1 2 0 -0.0013 9 0 0 0 2.79E+07 3.24E+07 - - - 2.8012 0.9937 221125_WJC_METTL3_EV_vs_WT_F01.16062.16062.2 0.000171 26-Nov F.LLIGGGTAAFAAAR[166.11].S "sp|O95831|AIFM1_HUMAN,tr|A0A6Q8PFW2|A0A6Q8PFW2_HUMAN,tr|A0A6Q8PFA7|A0A6Q8PFA7_HUMAN,tr|A0A6Q8PHJ9|A0A6Q8PHJ9_HUMAN,tr|A0A6Q8PFS4|A0A6Q8PFS4_HUMAN,tr|A0A7I2PK44|A0A7I2PK44_HUMAN,tr|A0A6Q8PF87|A0A6Q8PF87_HUMAN,tr|A0A6Q8PG15|A0A6Q8PG15_HUMAN,tr|A0A6Q8PFE1|A0A6Q8PFE1_HUMAN,tr|A0A7I2RLJ8|A0A7I2RLJ8_HUMAN,tr|A0A6Q8PFQ8|A0A6Q8PFQ8_HUMAN,tr|A0A6Q8PHC0|A0A6Q8PHC0_HUMAN,tr|A0A6Q8PFM5|A0A6Q8PFM5_HUMAN" 13 1297.7382 0.6 4278 16062 2 1297.738465 649.8764 "Apoptosis-inducing factor 1, mitochondrial OS=Homo sapiens OX=9606 GN=AIFM1 PE=1 SV=1" 9.75 3274.4 - 708073 - - - 0.2119 - 2.186 0.561 - 291.7 1 1 0 0.0003 14 0 0 0 8.93E+06 1.50E+07 - - - 5.147 0.9992 221125_WJC_METTL3_EV_vs_WT_F01.16066.16066.2 0.00325 14-Oct R.IPQLLLER[166.11].Y "sp|Q7L2E3|DHX30_HUMAN,tr|H7BXY3|H7BXY3_HUMAN" 2 990.6101 1.31 4281 16066 2 990.607881 496.3123 ATP-dependent RNA helicase DHX30 OS=Homo sapiens OX=9606 GN=DHX30 PE=1 SV=1 6 3274.9 - 767923 - - - -2.2764 - 1.959 0.343 - 293.7 1 2 0 -0.0023 8 0 0 0 1.24E+08 9.43E+07 - - - 3.6017 0.9968 221125_WJC_METTL3_EV_vs_WT_F01.16067.16067.2 0.0135 16-Jul K.FEDENFILK[136.11].H "sp|P62937|PPIA_HUMAN,tr|C9J5S7|C9J5S7_HUMAN,tr|A0A7I2V4V1|A0A7I2V4V1_HUMAN,tr|F8WE65|F8WE65_HUMAN" 4 1161.5797 0.61 4282 16067 2 1161.581037 581.7971 Peptidyl-prolyl cis-trans isomerase A OS=Homo sapiens OX=9606 GN=PPIA PE=1 SV=2 4.14 3275 - 352370 - - - 1.1166 - 1.348 0.242 - 90.6 1 2 0 0.0013 9 0 0 0 5.02E+06 8.17E+06 - - - 1.6919 0.9945 221125_WJC_METTL3_EV_vs_WT_F01.16072.16072.2 0.554 14-Nov R.IPQLLLER.Y "sp|Q7L2E3|DHX30_HUMAN,tr|H7BXY3|H7BXY3_HUMAN" 2 980.6019 1.31 4285 16072 2 980.60605 491.3082 ATP-dependent RNA helicase DHX30 OS=Homo sapiens OX=9606 GN=DHX30 PE=1 SV=1 6 3275.6 - 799695 - - - 4.2668 - 1.929 0.279 - 466.9 1 2 0 0.0042 8 0 0 0 1.24E+08 9.43E+07 - - - 3.0819 0.9982 221125_WJC_METTL3_EV_vs_WT_F01.16073.16073.2 0.000129 16-Oct R.FLIIDEADR[166.11].M sp|Q8N8A6|DDX51_HUMAN 1 1100.5741 1 4286 16073 2 1100.569687 551.2943 ATP-dependent RNA helicase DDX51 OS=Homo sapiens OX=9606 GN=DDX51 PE=1 SV=3 4.03 3275.7 - 510934 - - - -4.0506 - 1.962 0.43 - 338.6 1 2 0 -0.0045 9 0 0 0 2.72E+07 2.71E+07 - - - 4.1654 0.9541 221125_WJC_METTL3_EV_vs_WT_F01.16079.16079.2 0.482 20-Jul R.LLEQMGALAVR.G "sp|Q96IU2|ZBED3_HUMAN,tr|D6RIC4|D6RIC4_HUMAN" 2 1199.6696 1.54 4291 16079 2 1199.666237 600.8421 Zinc finger BED domain-containing protein 3 OS=Homo sapiens OX=9606 GN=ZBED3 PE=1 SV=1 6 3276.4 - 546477 - - - -2.8266 - 1.399 0.11 - 119.8 4 2 0 -0.0034 11 0 0 0 1.29E+07 8.35E+06 - - - 0.4918 0.9984 221125_WJC_METTL3_EV_vs_WT_F01.16087.16087.2 1.52 14-Sep K.ALDYYMLR[166.11].N sp|Q9Y490|TLN1_HUMAN 1 1053.5193 0.73 4297 16087 2 1053.518469 527.7669 Talin-1 OS=Homo sapiens OX=9606 GN=TLN1 PE=1 SV=3 5.88 3277.3 - 1.19E+06 - - - -0.7622 - 1.509 0.241 - 370.2 1 2 0 -0.0008 8 0 0 0 1.48E+07 2.04E+07 - - - 2.0617 0.9993 221125_WJC_METTL3_EV_vs_WT_F01.16098.16098.2 0.00237 18-Sep K.FAAQELIEVK[136.11].R "sp|Q86U44|MTA70_HUMAN,tr|F5H6D8|F5H6D8_HUMAN,tr|H0YFV6|H0YFV6_HUMAN,tr|B4DTN4|B4DTN4_HUMAN" 4 1154.6427 0.42 4305 16098 2 1154.641305 578.3286 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 4.53 3278.6 - 453458 - - - -1.1865 - 1.419 0.389 - 152.5 1 2 0 -0.0014 10 0 0 0 1.39E+07 3.27E+07 - - - 2.8905 0.9284 221125_WJC_METTL3_EV_vs_WT_F01.16105.16105.2 0.044 22-Jul L.C[160.03]LEK[136.11]PLGPSVLR[166.11].H sp|Q9H790|EXO5_HUMAN 1 1385.782 0.8 4309 16105 2 1385.780841 693.8983 Exonuclease V OS=Homo sapiens OX=9606 GN=EXO5 PE=1 SV=1 8.22 3279.5 - 424243 - - - -0.819 - 1.279 0.347 - 102.4 1 1 0 -0.0011 12 0 0 0 1.75E+07 2.17E+07 - - - 2.2511 0.9989 221125_WJC_METTL3_EV_vs_WT_F01.16113.16113.2 0.0919 20-Jun R.LVMELSGEMVR[166.11].K "sp|O75306|NDUS2_HUMAN,tr|A0A7I2V4X8|A0A7I2V4X8_HUMAN,tr|A0A7I2V4G5|A0A7I2V4G5_HUMAN,tr|A0A7I2V5D5|A0A7I2V5D5_HUMAN,tr|A0A7I2YQG7|A0A7I2YQG7_HUMAN,tr|A0A7I2V596|A0A7I2V596_HUMAN,tr|A0A7I2V5G4|A0A7I2V5G4_HUMAN,tr|A0A7I2V410|A0A7I2V410_HUMAN,tr|A0A7I2V630|A0A7I2V630_HUMAN,tr|A0A7I2V2B9|A0A7I2V2B9_HUMAN,tr|A0A7I2YQD8|A0A7I2YQD8_HUMAN,tr|A0A7I2V517|A0A7I2V517_HUMAN,tr|A0A7I2V3J6|A0A7I2V3J6_HUMAN,tr|A0A7I2V5E2|A0A7I2V5E2_HUMAN,tr|A0A7I2V4W5|A0A7I2V4W5_HUMAN" 15 1272.6445 0.87 4314 16113 2 1272.645529 637.3296 "NADH dehydrogenase [ubiquinone] iron-sulfur protein 2, mitochondrial OS=Homo sapiens OX=9606 GN=NDUFS2 PE=1 SV=2" 4.53 3280.5 - 406840 - - - 0.7701 - 1.445 0.322 - 62.9 1 2 0 0.001 11 0 0 0 6.02E+06 6.89E+06 - - - 2.4148 0.9998 221125_WJC_METTL3_EV_vs_WT_F01.16116.16116.2 0.000649 20-Dec K.ILITTVPPNLR.K "sp|Q12905|ILF2_HUMAN,tr|B4DY09|B4DY09_HUMAN" 2 1235.7602 1.71 4316 16116 2 1235.759909 618.8874 Interleukin enhancer-binding factor 2 OS=Homo sapiens OX=9606 GN=ILF2 PE=1 SV=2 9.75 3280.9 - 1.45E+06 - - - -0.2015 - 2.233 0.367 - 515.1 1 2 0 -0.0002 11 0 0 0 5.70E+07 3.33E+07 - - - 3.9248 0.9997 221125_WJC_METTL3_EV_vs_WT_F01.16117.16117.2 0.0861 20-Oct K.ILITTVPPNLR[166.11].K "sp|Q12905|ILF2_HUMAN,tr|B4DY09|B4DY09_HUMAN" 2 1245.7684 1.81 4317 16117 2 1245.766982 623.8915 Interleukin enhancer-binding factor 2 OS=Homo sapiens OX=9606 GN=ILF2 PE=1 SV=2 9.75 3281 - 1.30E+06 - - - -1.1607 - 1.96 0.391 - 369.2 1 2 0 -0.0014 11 0 0 0 5.92E+07 3.27E+07 - - - 3.7489 0.9978 221125_WJC_METTL3_EV_vs_WT_F01.16118.16118.2 0.0192 12-Jun K.LFDFPGR[166.11].G sp|Q9P258|RCC2_HUMAN 1 860.442 0.43 4318 16118 2 860.441094 431.2283 Protein RCC2 OS=Homo sapiens OX=9606 GN=RCC2 PE=1 SV=2 5.84 3281.1 - 1.46E+06 - - - -1.0622 - 1.14 0.327 - 100.9 1 2 0 -0.0009 7 0 0 0 1.99E+07 4.59E+07 - - - 1.8711 0.9995 221125_WJC_METTL3_EV_vs_WT_F01.16119.16119.2 0.014 20-Oct K.ALTLIAGSPLK[136.11].L "sp|Q86VP6|CAND1_HUMAN,tr|A0A0C4DGH5|A0A0C4DGH5_HUMAN" 2 1090.6841 0.75 4319 16119 2 1090.683068 546.3493 Cullin-associated NEDD8-dissociated protein 1 OS=Homo sapiens OX=9606 GN=CAND1 PE=1 SV=2 8.8 3281.2 - 908560 - - - -0.9884 - 2.045 0.31 - 271.6 1 2 0 -0.0011 11 0 0 0 1.90E+07 2.54E+07 - - - 3.2656 0.9986 221125_WJC_METTL3_EV_vs_WT_F01.16126.16126.2 0.00529 20-Oct K.ALTLIAGSPLK.L "sp|Q86VP6|CAND1_HUMAN,tr|A0A0C4DGH5|A0A0C4DGH5_HUMAN" 2 1082.6699 0.75 4322 16126 2 1082.667754 542.3422 Cullin-associated NEDD8-dissociated protein 1 OS=Homo sapiens OX=9606 GN=CAND1 PE=1 SV=2 8.8 3282.1 - 838816 - - - -2.0246 - 2.068 0.242 - 304.8 1 2 0 -0.0022 11 0 0 0 1.90E+07 2.54E+07 - - - 2.7933 0.9996 221125_WJC_METTL3_EV_vs_WT_F01.16127.16127.2 0.0853 20-Oct R.ILLLGEAQVGK[136.11].T "sp|Q8IXI1|MIRO2_HUMAN,tr|I3L2C6|I3L2C6_HUMAN,tr|H3BST5|H3BST5_HUMAN,tr|H3BUX4|H3BUX4_HUMAN,tr|H3BMP9|H3BMP9_HUMAN,tr|H3BVI5|H3BVI5_HUMAN" 6 1147.7056 0.82 4323 16127 2 1147.706875 574.8601 Mitochondrial Rho GTPase 2 OS=Homo sapiens OX=9606 GN=RHOT2 PE=1 SV=2 6 3282.2 - 430900 - - - 1.1022 - 2.13 0.352 - 259.7 1 2 0 0.0013 11 0 0 0 4.39E+06 5.34E+06 - - - 3.686 0.9647 221125_WJC_METTL3_EV_vs_WT_F01.16128.16128.2 0.0136 18-Aug K.FAYVPFGAGR[166.11].H "sp|Q16850|CP51A_HUMAN,tr|H7C0D0|H7C0D0_HUMAN" 2 1093.5584 0.18 4324 16128 2 1094.559754 547.7865 Lanosterol 14-alpha demethylase OS=Homo sapiens OX=9606 GN=CYP51A1 PE=1 SV=4 8.75 3282.3 - 524171 - - - 915.652 - 1.794 0.374 - 165.2 1 2 0 1.0013 10 0 0 0 6.72E+05 3.77E+06 - - - 3.1203 0.9993 221125_WJC_METTL3_EV_vs_WT_F01.16131.16131.2 0.0142 14-Jul R.VDEIIWVK[136.11].T sp|Q86U44|MTA70_HUMAN 1 1008.5735 0.03 4325 16131 2 1008.573191 505.294 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 4.37 3282.7 - 1.50E+09 - - - -0.3391 - 1.839 0.251 - 152.1 1 2 0 -0.0003 8 0 0 0 1.35E+10 4.88E+11 - - - 2.7322 0.9993 221125_WJC_METTL3_EV_vs_WT_F01.16142.16142.2 0.0358 14-Aug R.VAFTLLEK.V "sp|O15498|YKT6_HUMAN,tr|A0A7I2V4L6|A0A7I2V4L6_HUMAN,tr|A0A7I2V3V7|A0A7I2V3V7_HUMAN,tr|A0A7I2V3A1|A0A7I2V3A1_HUMAN" 4 919.5379 12.76 4333 16142 2 919.538339 460.7762 Synaptobrevin homolog YKT6 OS=Homo sapiens OX=9606 GN=YKT6 PE=1 SV=1 5.97 3283.9 - 1.25E+06 - - - 0.5111 - 1.769 0.277 - 177 1 2 0 0.0005 8 0 0 0 2.43E+08 1.91E+07 - - - 2.8071 0.9988 221125_WJC_METTL3_EV_vs_WT_F01.16170.16170.2 0.145 14-Aug K.WISIMTER.S "sp|P07355|ANXA2_HUMAN,sp|A6NMY6|AXA2L_HUMAN,tr|H0YL33|H0YL33_HUMAN,tr|H0YMU9|H0YMU9_HUMAN,tr|H0YM50|H0YM50_HUMAN,tr|H0YMD0|H0YMD0_HUMAN,tr|H0YMW4|H0YMW4_HUMAN,tr|H0YN42|H0YN42_HUMAN,tr|H0YN28|H0YN28_HUMAN,tr|H0YNP5|H0YNP5_HUMAN" 10 1034.5219 53.82 4342 16170 2 1034.520689 518.2682 Annexin A2 OS=Homo sapiens OX=9606 GN=ANXA2 PE=1 SV=2 6 3287.8 - 3.77E+06 - - - -1.1716 - 1.514 0.289 - 175.4 1 2 0 -0.0012 8 0 0 0 1.71E+08 3.17E+06 - - - 2.4261 0.9252 221125_WJC_METTL3_EV_vs_WT_F01.16180.16180.2 0.0533 18-Jun D.VDEATGAVKK[136.11].H sp|Q96ST3|SIN3A_HUMAN 1 1024.5644 - 4344 16180 2 1024.565201 513.2895 Paired amphipathic helix protein Sin3a OS=Homo sapiens OX=9606 GN=SIN3A PE=1 SV=2 6.04 3289.2 - 6.10E+06 - - - 0.7574 - 1.525 0.277 - 74.9 1 1 0 0.0008 10 0 0 0 - - - - - 2.2646 0.9999 221125_WJC_METTL3_EV_vs_WT_F01.16182.16182.2 5.20E-07 13/22 K.VFGAAPLENVVR.K "sp|Q16656|NRF1_HUMAN,tr|C9JP85|C9JP85_HUMAN" 2 1270.7034 2.79 4345 16182 2 1270.704136 636.359 Nuclear respiratory factor 1 OS=Homo sapiens OX=9606 GN=NRF1 PE=1 SV=1 5.97 3289.4 - 5.05E+06 - - - 0.602 - 2.408 0.477 - 517.9 1 2 0 0.0008 12 0 0 0 5.38E+08 1.93E+08 - - - 4.8761 0.9973 221125_WJC_METTL3_EV_vs_WT_F01.16187.16187.2 0.00138 18-Oct K.LFDAPLSISK.R "sp|Q9NQA3|WASH6_HUMAN,sp|A8K0Z3|WASH1_HUMAN,sp|A8MWX3|WASH4_HUMAN,sp|C4AMC7|WASH3_HUMAN,sp|Q6VEQ5|WASH2_HUMAN,tr|A0A7I2YQU6|A0A7I2YQU6_HUMAN" 6 1089.607 3.66 4347 16187 2 1089.60333 545.8108 WAS protein family homolog 6 OS=Homo sapiens OX=9606 GN=WASH6P PE=1 SV=3 5.84 3290.1 - 0 - - - -3.3783 - 1.689 0.352 - 262.8 1 2 0 -0.0037 10 0 0 0 4.05E+07 1.11E+07 - - - 3.1027 0.9997 221125_WJC_METTL3_EV_vs_WT_F01.16191.16191.2 0.000385 13/24 K.VLIIGGGDGGVLR[166.11].E "sp|P19623|SPEE_HUMAN,tr|K7ESL0|K7ESL0_HUMAN" 2 1234.7273 0.14 4349 16191 2 1234.726818 618.3709 Spermidine synthase OS=Homo sapiens OX=9606 GN=SRM PE=1 SV=1 5.81 3290.5 - 2.44E+06 - - - -0.3831 - 2.263 0.358 - 514.8 1 2 0 -0.0005 13 0 0 0 1.48E+07 1.06E+08 - - - 3.7811 0.997 221125_WJC_METTL3_EV_vs_WT_F01.16192.16192.2 0.00233 13/22 K.VFGAAPLENVVR[166.11].K "sp|Q16656|NRF1_HUMAN,tr|C9JP85|C9JP85_HUMAN" 2 1280.7116 2.79 4350 16192 2 1280.705262 641.3631 Nuclear respiratory factor 1 OS=Homo sapiens OX=9606 GN=NRF1 PE=1 SV=1 5.97 3290.7 - 3.66E+06 - - - -4.9808 - 2.345 0.427 - 487.1 1 2 0 -0.0064 12 0 0 0 5.38E+08 1.93E+08 - - - 4.4353 0.9989 221125_WJC_METTL3_EV_vs_WT_F01.16198.16198.2 0.0128 12-Aug R.FVAELWK[136.11].D sp|P35580|MYH10_HUMAN 1 899.4996 0.89 4352 16198 2 899.498315 450.7571 Myosin-10 OS=Homo sapiens OX=9606 GN=MYH10 PE=1 SV=3 6 3291.4 - 2.90E+06 - - - -1.473 - 1.649 0.276 - 181.1 1 2 0 -0.0013 7 0 0 0 2.21E+08 2.48E+08 - - - 2.6639 0.9869 221125_WJC_METTL3_EV_vs_WT_F01.16205.16205.2 0.169 12-Jul R.FVAELWK.D sp|P35580|MYH10_HUMAN 1 891.4854 0.89 4354 16205 2 891.481492 446.75 Myosin-10 OS=Homo sapiens OX=9606 GN=MYH10 PE=1 SV=3 6 3292.4 - 3.45E+06 - - - -4.4286 - 1.527 0.264 - 143.7 1 2 0 -0.0039 7 0 0 0 2.21E+08 2.48E+08 - - - 2.3309 0.9998 221125_WJC_METTL3_EV_vs_WT_F01.16207.16207.2 8.51E-06 18-Nov R.GTPLISPLIK[136.11].W "sp|P49327|FAS_HUMAN,tr|A0A0U1RQF0|A0A0U1RQF0_HUMAN" 2 1045.6627 0.56 4355 16207 2 1045.663992 523.8386 Fatty acid synthase OS=Homo sapiens OX=9606 GN=FASN PE=1 SV=3 8.75 3292.6 - 3.54E+06 - - - 1.2528 - 1.855 0.524 - 470.4 1 2 0 0.0013 10 0 0 0 1.06E+08 1.91E+08 - - - 4.6356 0.9994 221125_WJC_METTL3_EV_vs_WT_F01.16215.16215.2 0.004 12-Jul K.FTVPMLK.E "sp|P12956|XRCC6_HUMAN,tr|B1AHC9|B1AHC9_HUMAN" 2 834.4673 1 4358 16215 2 834.4678 418.2409 X-ray repair cross-complementing protein 6 OS=Homo sapiens OX=9606 GN=XRCC6 PE=1 SV=2 8.75 3293.6 - 0 - - - 0.5429 - 1.543 0.338 - 157.5 1 2 0 0.0005 7 0 0 0 1.47E+08 1.48E+08 - - - 2.9116 0.9868 221125_WJC_METTL3_EV_vs_WT_F01.16219.16219.2 0.0143 14-Aug K.FIC[160.03]ISDLR.A sp|Q6P2Q9|PRP8_HUMAN 1 1022.5219 0.38 4360 16219 2 1022.516284 512.2682 Pre-mRNA-processing-splicing factor 8 OS=Homo sapiens OX=9606 GN=PRPF8 PE=1 SV=2 5.83 3294.1 - 2.67E+06 - - - -5.4943 - 1.561 0.36 - 224.6 1 2 0 -0.0056 8 0 0 0 7.11E+07 1.89E+08 - - - 3.0413 0.9993 221125_WJC_METTL3_EV_vs_WT_F01.16231.16231.2 0.00022 18-Oct R.LYLINSPVVR[166.11].A "sp|P41252|SYIC_HUMAN,tr|A0A804HL54|A0A804HL54_HUMAN,tr|A0A804HKU1|A0A804HKU1_HUMAN,tr|A0A804HK69|A0A804HK69_HUMAN,tr|A0A804HIV9|A0A804HIV9_HUMAN,tr|A0A804HJN6|A0A804HJN6_HUMAN,tr|A0A804HHW9|A0A804HHW9_HUMAN,tr|A0A0A0MSX9|A0A0A0MSX9_HUMAN,tr|J3KR24|J3KR24_HUMAN,tr|A0A804HJ36|A0A804HJ36_HUMAN" 10 1182.7 0.82 4365 16231 2 1182.698915 592.3573 "Isoleucine--tRNA ligase, cytoplasmic OS=Homo sapiens OX=9606 GN=IARS1 PE=1 SV=2" 8.75 3295.6 - 2.91E+06 - - - -0.9292 - 1.969 0.265 - 424.7 1 2 0 -0.0011 10 0 0 0 1.75E+08 2.13E+08 - - - 2.8891 0.9996 221125_WJC_METTL3_EV_vs_WT_F01.16235.16235.2 0.000715 18-Oct R.GTPLISPLIK.W "sp|P49327|FAS_HUMAN,tr|A0A0U1RQF0|A0A0U1RQF0_HUMAN" 2 1037.6485 0.56 4367 16235 2 1037.650013 519.8315 Fatty acid synthase OS=Homo sapiens OX=9606 GN=FASN PE=1 SV=3 8.75 3296 - 3.07E+06 - - - 1.4755 - 1.965 0.394 - 370.5 1 2 0 0.0015 10 0 0 0 1.06E+08 1.91E+08 - - - 3.8361 0.9994 221125_WJC_METTL3_EV_vs_WT_F01.16244.16244.2 0.0942 14-Aug R.VAFTLLEK[136.11].V "sp|O15498|YKT6_HUMAN,tr|A0A7I2V4L6|A0A7I2V4L6_HUMAN,tr|A0A7I2V3V7|A0A7I2V3V7_HUMAN,tr|A0A7I2V3A1|A0A7I2V3A1_HUMAN" 4 927.5521 12.73 4371 16244 2 927.552036 464.7833 Synaptobrevin homolog YKT6 OS=Homo sapiens OX=9606 GN=YKT6 PE=1 SV=1 5.97 3297.1 - 988571 - - - -0.0356 - 1.681 0.304 - 183.2 1 2 0 0 8 0 0 0 2.34E+08 1.84E+07 - - - 2.8528 0.9914 221125_WJC_METTL3_EV_vs_WT_F01.16248.16248.2 0.000274 20-Dec K.PVTALEYTFSR[166.11].S "sp|P54709|AT1B3_HUMAN,tr|C9JA36|C9JA36_HUMAN,tr|C9JXZ1|C9JXZ1_HUMAN" 3 1292.664 2.52 4373 16248 2 1292.662716 647.3393 Sodium\potassium-transporting ATPase subunit beta-3 OS=Homo sapiens OX=9606 GN=ATP1B3 PE=1 SV=1 6.43 3297.6 - 0 - - - -1.0103 - 2.554 0.446 - 448.7 1 1 0 -0.0013 11 0 0 0 2.51E+07 9.99E+06 - - - 4.8713 0.9993 221125_WJC_METTL3_EV_vs_WT_F01.16250.16250.2 0.0465 12-Jul K.LMIWDTR[166.11].S "sp|Q09028|RBBP4_HUMAN,sp|Q16576|RBBP7_HUMAN,tr|H0YCT5|H0YCT5_HUMAN,tr|H0YDK2|H0YDK2_HUMAN,tr|Q5JP02|Q5JP02_HUMAN,tr|Q5JP01|Q5JP01_HUMAN,tr|H0YF10|H0YF10_HUMAN,tr|E9PC52|E9PC52_HUMAN" 8 943.4825 1.2 4375 16250 2 943.483383 472.7485 Histone-binding protein RBBP4 OS=Homo sapiens OX=9606 GN=RBBP4 PE=1 SV=3 5.84 3297.9 - 1.53E+06 - - - 0.9433 - 1.463 0.36 - 203.3 1 2 0 0.0009 7 0 0 0 4.23E+08 3.53E+08 - - - 2.9053 0.9977 221125_WJC_METTL3_EV_vs_WT_F01.16263.16263.2 0.0702 12-Jun K.FTVPMLK[136.11].E "sp|P12956|XRCC6_HUMAN,tr|B1AHC9|B1AHC9_HUMAN" 2 842.4815 0.99 4380 16263 2 842.482472 422.248 X-ray repair cross-complementing protein 6 OS=Homo sapiens OX=9606 GN=XRCC6 PE=1 SV=2 8.75 3299.6 - 2.27E+06 - - - 1.0979 - 1.251 0.296 - 132.6 1 2 0 0.0009 7 0 0 0 1.47E+08 1.48E+08 - - - 1.9365 0.9995 221125_WJC_METTL3_EV_vs_WT_F01.16267.16267.2 0.0249 14-Aug R.VDEIIWVK.T sp|Q86U44|MTA70_HUMAN 1 1000.5593 0.03 4381 16267 2 1000.558765 501.2869 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 4.37 3300.2 - 5.96E+07 - - - -0.5677 - 2.001 0.272 - 195.2 1 2 0 -0.0006 8 0 0 0 1.35E+10 4.91E+11 - - - 3.1418 0.9742 221125_WJC_METTL3_EV_vs_WT_F01.16268.16268.2 0.11 12-Jul K.LMIWDTR.S "sp|Q09028|RBBP4_HUMAN,sp|Q16576|RBBP7_HUMAN,tr|H0YCT5|H0YCT5_HUMAN,tr|H0YDK2|H0YDK2_HUMAN,tr|Q5JP02|Q5JP02_HUMAN,tr|Q5JP01|Q5JP01_HUMAN,tr|H0YF10|H0YF10_HUMAN,tr|E9PC52|E9PC52_HUMAN" 8 933.4742 1.2 4382 16268 2 933.468792 467.7444 Histone-binding protein RBBP4 OS=Homo sapiens OX=9606 GN=RBBP4 PE=1 SV=3 5.84 3300.3 - 3.46E+06 - - - -5.8181 - 1.441 0.326 - 273.2 1 2 0 -0.0054 7 0 0 0 4.23E+08 3.53E+08 - - - 2.6047 0.9991 221125_WJC_METTL3_EV_vs_WT_F01.16269.16269.2 0.0531 16-Aug R.VLIFSQMTK[136.11].M "sp|Q14839|CHD4_HUMAN,sp|Q8TDI0|CHD5_HUMAN,sp|Q12873|CHD3_HUMAN,tr|A0A2R8Y4X2|A0A2R8Y4X2_HUMAN,tr|A0A2U3TZM0|A0A2U3TZM0_HUMAN,tr|A0A2R8Y685|A0A2R8Y685_HUMAN,tr|A0A2R8Y445|A0A2R8Y445_HUMAN,tr|F2Z2R5|F2Z2R5_HUMAN,tr|A0A2R8YD40|A0A2R8YD40_HUMAN,tr|A0A2R8Y5J0|A0A2R8Y5J0_HUMAN,tr|A0A2R8Y425|A0A2R8Y425_HUMAN,tr|A0A2R8YFK9|A0A2R8YFK9_HUMAN,tr|A0A2R8Y8B3|A0A2R8Y8B3_HUMAN,tr|A0A2R8Y8C1|A0A2R8Y8C1_HUMAN,tr|A0A0C4DGG9|A0A0C4DGG9_HUMAN,tr|A0A2R8YFD8|A0A2R8YFD8_HUMAN,tr|A0A2R8YDW2|A0A2R8YDW2_HUMAN,tr|A0A2R8Y5Z7|A0A2R8Y5Z7_HUMAN,tr|A0A5F9ZHX5|A0A5F9ZHX5_HUMAN,tr|F5GWX5|F5GWX5_HUMAN,tr|K7EMY3|K7EMY3_HUMAN,tr|A0A2R8YER1|A0A2R8YER1_HUMAN,tr|A0A2R8Y521|A0A2R8Y521_HUMAN,tr|A0A2R8YDJ9|A0A2R8YDJ9_HUMAN,tr|A0A2R8Y212|A0A2R8Y212_HUMAN" 25 1073.6035 17.47 4383 16269 2 1073.604385 537.809 Chromodomain-helicase-DNA-binding protein 4 OS=Homo sapiens OX=9606 GN=CHD4 PE=1 SV=2 8.72 3300.4 - 950967 - - - 0.8681 - 1.649 0.288 - 184.9 1 2 0 0.0009 9 0 0 0 1.10E+08 6.29E+06 - - - 2.6149 0.9995 221125_WJC_METTL3_EV_vs_WT_F01.16274.16274.2 0.001 16-Oct R.IMEAIELYR[166.11].E sp|Q9UNX4|WDR3_HUMAN 1 1146.5983 1.29 4385 16274 2 1146.595587 574.3064 WD repeat-containing protein 3 OS=Homo sapiens OX=9606 GN=WDR3 PE=1 SV=1 4.53 3301.1 - 1.06E+06 - - - -2.3234 - 2.138 0.386 - 318.1 1 2 0 -0.0027 9 0 0 0 1.97E+07 1.53E+07 - - - 4.0895 0.9992 221125_WJC_METTL3_EV_vs_WT_F01.16275.16275.2 0.00138 16-Dec K.LLC[160.03]GLLAER[166.11].L sp|P14174|MIF_HUMAN 1 1053.588 1.01 4386 16275 2 1053.586724 527.8013 Macrophage migration inhibitory factor OS=Homo sapiens OX=9606 GN=MIF PE=1 SV=4 5.99 3301.2 - 4.62E+06 - - - -1.231 - 2.252 0.205 - 492.9 1 2 0 -0.0013 9 0 0 0 1.37E+08 1.36E+08 - - - 2.9034 0.98 221125_WJC_METTL3_EV_vs_WT_F01.16276.16276.2 0.000243 16-Sep R.EGLEYIPLR.H "sp|Q15392|DHC24_HUMAN,tr|A0A0A0MTI1|A0A0A0MTI1_HUMAN" 2 1088.5866 1.4 4387 16276 2 1088.578802 545.3006 Delta(24)-sterol reductase OS=Homo sapiens OX=9606 GN=DHCR24 PE=1 SV=2 4.53 3301.3 - 1.52E+06 - - - -7.1726 - 2.063 0.366 - 250.4 1 2 0 -0.0078 9 0 0 0 2.48E+07 1.77E+07 - - - 3.8369 0.9999 221125_WJC_METTL3_EV_vs_WT_F01.16277.16277.2 6.33E-05 16-Sep R.EGLEYIPLR[166.11].H "sp|Q15392|DHC24_HUMAN,tr|A0A0A0MTI1|A0A0A0MTI1_HUMAN" 2 1098.5949 1.44 4388 16277 2 1098.59459 550.3047 Delta(24)-sterol reductase OS=Homo sapiens OX=9606 GN=DHCR24 PE=1 SV=2 4.53 3301.4 - 829779 - - - -0.264 - 2.128 0.46 - 305.8 1 2 0 -0.0003 9 0 0 0 2.56E+07 1.77E+07 - - - 4.6233 0.9813 221125_WJC_METTL3_EV_vs_WT_F01.16280.16280.2 2.97 12-Jun R.DLIDYVR.Y "sp|Q9Y3C1|NOP16_HUMAN,tr|A0A0C4DGU5|A0A0C4DGU5_HUMAN,tr|D6RIC3|D6RIC3_HUMAN,tr|A0A087X2G6|A0A087X2G6_HUMAN" 4 892.4654 0.69 4389 16280 2 892.464068 447.24 Nucleolar protein 16 OS=Homo sapiens OX=9606 GN=NOP16 PE=1 SV=2 4.21 3301.8 - 1.57E+06 - - - -1.5284 - 1.213 0.115 - 165.2 1 2 0 -0.0014 7 0 0 0 3.37E+07 4.89E+07 - - - 0.5018 0.9909 221125_WJC_METTL3_EV_vs_WT_F01.16281.16281.2 1.24 12-Jul R.LYEFIVR.H sp|Q13472|TOP3A_HUMAN 1 938.5226 3.58 4390 16281 2 938.521616 470.2686 DNA topoisomerase 3-alpha OS=Homo sapiens OX=9606 GN=TOP3A PE=1 SV=1 6 3302 - 760061 - - - -0.9984 - 1.355 0.109 - 135.8 1 2 0 -0.0009 7 0 0 0 1.71E+07 4.77E+06 - - - 0.8084 0.9889 221125_WJC_METTL3_EV_vs_WT_F01.16282.16282.2 5.03 18-Sep R.LYLINSPVVR.A "sp|P41252|SYIC_HUMAN,tr|A0A804HL54|A0A804HL54_HUMAN,tr|A0A804HKU1|A0A804HKU1_HUMAN,tr|A0A804HK69|A0A804HK69_HUMAN,tr|A0A804HIV9|A0A804HIV9_HUMAN,tr|A0A804HJN6|A0A804HJN6_HUMAN,tr|A0A804HHW9|A0A804HHW9_HUMAN,tr|A0A0A0MSX9|A0A0A0MSX9_HUMAN,tr|J3KR24|J3KR24_HUMAN,tr|A0A804HJ36|A0A804HJ36_HUMAN" 10 1172.6917 0.82 4391 16282 2 1172.687981 587.3531 "Isoleucine--tRNA ligase, cytoplasmic OS=Homo sapiens OX=9606 GN=IARS1 PE=1 SV=2" 8.75 3302 - 6.36E+06 - - - -3.2089 - 1.774 0.148 - 312.6 1 2 0 -0.0038 10 0 0 0 1.75E+08 2.13E+08 - - - 1.733 0.9903 221125_WJC_METTL3_EV_vs_WT_F01.16284.16284.2 1.33 12-Jul R.LTLLQLK.G sp|Q8NHP8|PLBL2_HUMAN 1 827.548 2.42 4393 16284 2 827.546948 414.7813 Putative phospholipase B-like 2 OS=Homo sapiens OX=9606 GN=PLBD2 PE=1 SV=2 8.75 3302.3 - 768893 - - - -1.3196 - 1.394 0.105 - 121.1 1 2 0 -0.0011 7 0 0 0 1.07E+07 4.43E+06 - - - 0.8687 0.9991 221125_WJC_METTL3_EV_vs_WT_F01.16292.16292.2 0.00263 16-Jul R.YVANLFPYK[136.11].G "sp|Q15181|IPYR_HUMAN,sp|Q9H2U2|IPYR2_HUMAN,tr|D6RGV9|D6RGV9_HUMAN,tr|Q5SQT6|Q5SQT6_HUMAN,tr|H0Y9D8|H0Y9D8_HUMAN,tr|D6RGI1|D6RGI1_HUMAN,tr|H0YAK2|H0YAK2_HUMAN" 7 1121.6001 0.47 4397 16292 2 1121.598661 561.8073 Inorganic pyrophosphatase OS=Homo sapiens OX=9606 GN=PPA1 PE=1 SV=2 8.5 3303.3 - 1.94E+06 - - - -1.2669 - 1.513 0.339 - 113.3 1 2 0 -0.0014 9 0 0 0 1.72E+07 3.68E+07 - - - 2.7424 0.9997 221125_WJC_METTL3_EV_vs_WT_F01.16293.16293.2 0.00889 18-Nov K.APGLGLVLER[166.11].V "sp|Q9Y606|TRUA_HUMAN,tr|G8JLB3|G8JLB3_HUMAN,tr|F5H1S9|F5H1S9_HUMAN" 3 1033.616 1.82 4398 16293 2 1033.614733 517.8153 tRNA pseudouridine synthase A OS=Homo sapiens OX=9606 GN=PUS1 PE=1 SV=3 6.05 3303.4 - 1.43E+06 - - - -1.1774 - 2.12 0.374 - 545.8 1 2 0 -0.0012 10 0 0 0 8.08E+07 4.45E+07 - - - 3.9004 0.9735 221125_WJC_METTL3_EV_vs_WT_F01.16301.16301.2 0.00179 16-Oct A.LDIEIATYR.K "sp|P08670|VIME_HUMAN,sp|Q86Y46|K2C73_HUMAN,sp|Q9NSB2|KRT84_HUMAN,sp|P14136|GFAP_HUMAN,sp|Q14533|KRT81_HUMAN,sp|Q6KB66|K2C80_HUMAN,sp|P05787|K2C8_HUMAN,sp|P41219|PERI_HUMAN,sp|P19013|K2C4_HUMAN,sp|P78386|KRT85_HUMAN,sp|Q9NSB4|KRT82_HUMAN,sp|P04264|K2C1_HUMAN,sp|O43790|KRT86_HUMAN,sp|P78385|KRT83_HUMAN,sp|P08729|K2C7_HUMAN,tr|A0A1W2PR46|A0A1W2PR46_HUMAN,tr|H7C5W5|H7C5W5_HUMAN,tr|A0A087X106|A0A087X106_HUMAN,tr|A0A1X7SBR3|A0A1X7SBR3_HUMAN,tr|A0A1W2PQU7|A0A1W2PQU7_HUMAN,tr|K7EJU1|K7EJU1_HUMAN,tr|A0A1X7SCE1|A0A1X7SCE1_HUMAN,tr|A0A1W2PRT3|A0A1W2PRT3_HUMAN,tr|A0A1W2PS58|A0A1W2PS58_HUMAN,tr|B0YJC5|B0YJC5_HUMAN,tr|F5GYI5|F5GYI5_HUMAN,tr|B0YJC4|B0YJC4_HUMAN,tr|H0YIC5|H0YIC5_HUMAN,tr|K7EPI4|K7EPI4_HUMAN,tr|K7EPT8|K7EPT8_HUMAN" 30 1092.5815 170.79 4403 16301 2 1092.580416 547.298 Vimentin OS=Homo sapiens OX=9606 GN=VIM PE=1 SV=4 4.37 3304.4 - 1.31E+06 - - - -1.015 - 2.123 0.285 - 306.5 1 1 0 -0.0011 9 0 0 0 4.21E+07 2.46E+05 - - - 3.3236 0.9384 221125_WJC_METTL3_EV_vs_WT_F01.16303.16303.2 4.36 14-Jul R.LGISSLIR[166.11].E sp|P35573|GDE_HUMAN 1 867.5417 0.16 4404 16303 2 867.539891 434.7781 Glycogen debranching enzyme OS=Homo sapiens OX=9606 GN=AGL PE=1 SV=3 9.75 3304.6 - 1.46E+06 - - - -2.1106 - 1.318 0.04 - 114.5 3 2 0 -0.0018 8 0 0 0 9.51E+06 6.03E+07 - - - -0.0445 0.995 221125_WJC_METTL3_EV_vs_WT_F01.16306.16306.2 0.332 14-Sep R.LGISSLIR.E sp|P35573|GDE_HUMAN 1 857.5335 0.23 4407 16306 2 857.534224 429.774 Glycogen debranching enzyme OS=Homo sapiens OX=9606 GN=AGL PE=1 SV=3 9.75 3305 - 880666 - - - 0.9003 - 1.595 0.112 - 204.9 1 2 0 0.0008 8 0 0 0 9.57E+06 4.13E+07 - - - 1.2761 0.9938 221125_WJC_METTL3_EV_vs_WT_F01.16307.16307.2 0.00206 20-Dec R.FGGLVLSPVGK.Q sp|Q9UJK0|TSR3_HUMAN 1 1072.6281 0.35 4408 16307 2 1072.621116 537.3213 18S rRNA aminocarboxypropyltransferase OS=Homo sapiens OX=9606 GN=TSR3 PE=1 SV=1 8.75 3305.2 - 818296 - - - -6.4934 - 2.414 0.478 - 499.6 1 2 0 -0.007 11 0 0 0 1.44E+07 4.11E+07 - - - 4.9534 0.9945 221125_WJC_METTL3_EV_vs_WT_F01.16309.16309.2 0.00395 18-Sep R.IFEPILGEGR.A "sp|P28340|DPOD1_HUMAN,tr|M0R3H8|M0R3H8_HUMAN,tr|M0QXQ2|M0QXQ2_HUMAN,tr|M0QXE6|M0QXE6_HUMAN,tr|M0R2B7|M0R2B7_HUMAN,tr|A0A087WYJ2|A0A087WYJ2_HUMAN" 6 1129.6132 0.67 4410 16309 2 1129.608246 565.8139 DNA polymerase delta catalytic subunit OS=Homo sapiens OX=9606 GN=POLD1 PE=1 SV=2 4.53 3305.4 - 675745 - - - -4.3493 - 1.789 0.331 - 253.5 1 2 0 -0.0049 10 0 0 0 6.51E+06 9.71E+06 - - - 3.1078 0.9999 221125_WJC_METTL3_EV_vs_WT_F01.16312.16312.2 5.75E-05 22-Sep R.MPGSVIPPPLVR.G sp|Q86YP4|P66A_HUMAN 1 1261.7217 17.02 4413 16312 2 1261.722052 631.8681 Transcriptional repressor p66-alpha OS=Homo sapiens OX=9606 GN=GATAD2A PE=1 SV=1 9.5 3305.8 - 412275 - - - 0.3075 - 2.109 0.502 - 193.4 1 2 0 0.0004 12 0 0 0 1.25E+07 7.32E+05 - - - 4.7121 1 221125_WJC_METTL3_EV_vs_WT_F01.16313.16313.2 7.29E-06 20-Nov Q.WGTLTDC[160.03]VVMR.D "sp|Q32P51|RA1L2_HUMAN,sp|P51991|ROA3_HUMAN,sp|P09651|ROA1_HUMAN,tr|A0A7I2V5D8|A0A7I2V5D8_HUMAN,tr|F8W646|F8W646_HUMAN,tr|A0A7I2V2R3|A0A7I2V2R3_HUMAN,tr|F8VZ49|F8VZ49_HUMAN,tr|A0A7I2V3R8|A0A7I2V3R8_HUMAN,tr|F8W6I7|F8W6I7_HUMAN,tr|A0A7I2V2L6|A0A7I2V2L6_HUMAN,tr|A0A7I2V4J6|A0A7I2V4J6_HUMAN,tr|A0A7I2V3W0|A0A7I2V3W0_HUMAN,tr|A0A7I2V4G0|A0A7I2V4G0_HUMAN,tr|A0A7I2V402|A0A7I2V402_HUMAN" 14 1336.6268 1.28 4414 16313 2 1336.62703 669.3207 Heterogeneous nuclear ribonucleoprotein A1-like 2 OS=Homo sapiens OX=9606 GN=HNRNPA1L2 PE=2 SV=2 5.83 3306 - 384762 - - - 0.1885 - 2.568 0.57 - 454.7 1 1 0 0.0003 11 0 0 0 2.66E+07 2.07E+07 - - - 5.8023 0.9995 221125_WJC_METTL3_EV_vs_WT_F01.16316.16316.2 0.0919 16-Oct K.MMLDDIVSR[166.11].G "sp|Q92945|FUBP2_HUMAN,tr|M0R0I5|M0R0I5_HUMAN,tr|M0QYH3|M0QYH3_HUMAN,tr|M0R0C6|M0R0C6_HUMAN,tr|M0QXW7|M0QXW7_HUMAN,tr|A0A087WTP3|A0A087WTP3_HUMAN" 6 1088.5234 0.93 4415 16316 2 1088.521343 545.269 Far upstream element-binding protein 2 OS=Homo sapiens OX=9606 GN=KHSRP PE=1 SV=4 4.21 3306.4 - 1.74E+06 - - - -1.864 - 1.947 0.368 - 480.1 1 2 0 -0.002 9 0 0 0 2.26E+07 2.42E+07 - - - 3.686 0.997 221125_WJC_METTL3_EV_vs_WT_F01.16317.16317.2 0.00102 16-Aug K.MMLDDIVSR.G "sp|Q92945|FUBP2_HUMAN,tr|M0R0I5|M0R0I5_HUMAN,tr|M0QYH3|M0QYH3_HUMAN,tr|M0R0C6|M0R0C6_HUMAN,tr|M0QXW7|M0QXW7_HUMAN,tr|A0A087WTP3|A0A087WTP3_HUMAN" 6 1078.5151 0.93 4416 16317 2 1078.511973 540.2648 Far upstream element-binding protein 2 OS=Homo sapiens OX=9606 GN=KHSRP PE=1 SV=4 4.21 3306.4 - 1.58E+06 - - - -2.9012 - 1.663 0.292 - 270.7 1 2 0 -0.0031 9 0 0 0 2.26E+07 2.42E+07 - - - 2.6682 0.9999 221125_WJC_METTL3_EV_vs_WT_F01.16318.16318.2 0.0149 18-Oct K.VYVIGSFVDK[136.11].S sp|Q7L0Y3|TM10C_HUMAN 1 1133.6212 0.97 4417 16318 2 1133.621238 567.8179 tRNA methyltransferase 10 homolog C OS=Homo sapiens OX=9606 GN=TRMT10C PE=1 SV=2 5.81 3306.6 - 1.26E+06 - - - 0.0238 - 2.148 0.475 - 361.4 1 2 0 0 10 0 0 0 2.06E+07 2.12E+07 - - - 4.6834 1 221125_WJC_METTL3_EV_vs_WT_F01.16319.16319.2 7.54E-06 20-Dec Q.WGTLTDC[160.03]VVMR[166.11].D "sp|Q32P51|RA1L2_HUMAN,sp|P51991|ROA3_HUMAN,sp|P09651|ROA1_HUMAN,tr|A0A7I2V5D8|A0A7I2V5D8_HUMAN,tr|F8W646|F8W646_HUMAN,tr|A0A7I2V2R3|A0A7I2V2R3_HUMAN,tr|F8VZ49|F8VZ49_HUMAN,tr|A0A7I2V3R8|A0A7I2V3R8_HUMAN,tr|F8W6I7|F8W6I7_HUMAN,tr|A0A7I2V2L6|A0A7I2V2L6_HUMAN,tr|A0A7I2V4J6|A0A7I2V4J6_HUMAN,tr|A0A7I2V3W0|A0A7I2V3W0_HUMAN,tr|A0A7I2V4G0|A0A7I2V4G0_HUMAN,tr|A0A7I2V402|A0A7I2V402_HUMAN" 14 1346.635 1.28 4418 16319 2 1346.632886 674.3248 Heterogeneous nuclear ribonucleoprotein A1-like 2 OS=Homo sapiens OX=9606 GN=HNRNPA1L2 PE=2 SV=2 5.83 3306.7 - 1.26E+06 - - - -1.6055 - 2.789 0.578 - 627.4 1 1 0 -0.0022 11 0 0 0 2.66E+07 2.07E+07 - - - 6.0841 0.9996 221125_WJC_METTL3_EV_vs_WT_F01.16320.16320.2 0.0338 12-Jul R.GFELTFK[136.11].T "sp|P39656|OST48_HUMAN,tr|U3KQ84|U3KQ84_HUMAN,tr|A0A0C4DGS1|A0A0C4DGS1_HUMAN" 3 848.4524 1.27 4419 16320 2 848.451865 425.2335 Dolichyl-diphosphooligosaccharide--protein glycosyltransferase 48 kDa subunit OS=Homo sapiens OX=9606 GN=DDOST PE=1 SV=4 6 3306.8 - 1.02E+06 - - - -0.5775 - 1.505 0.386 - 180.2 1 2 0 -0.0005 7 0 0 0 5.34E+07 4.19E+07 - - - 3.1871 0.9834 221125_WJC_METTL3_EV_vs_WT_F01.16321.16321.2 0.17 16-Jun K.EAGAIISTR.H "sp|Q6ZUV0|BACHL_HUMAN,sp|O00154|BACH_HUMAN,tr|K7EKP8|K7EKP8_HUMAN" 3 916.4978 4.21 4420 16321 2 916.494964 459.2562 Putative cytosolic acyl coenzyme A thioester hydrolase-like OS=Homo sapiens OX=9606 GN=ACOT7L PE=5 SV=1 6.1 3306.9 - 994601 - - - -3.0889 - 1.256 0.243 - 95.5 2 2 0 -0.0028 9 0 0 0 3.00E+07 7.11E+06 - - - 1.3599 0.9998 221125_WJC_METTL3_EV_vs_WT_F01.16326.16326.2 3.86E-07 22-Nov R.GYISPYFINTSK.G "sp|P10809|CH60_HUMAN,tr|A0A7I2V2X6|A0A7I2V2X6_HUMAN,tr|A0A7I2V599|A0A7I2V599_HUMAN,tr|A0A7I2YQ71|A0A7I2YQ71_HUMAN,tr|E7ESH4|E7ESH4_HUMAN,tr|A0A7I2V5M1|A0A7I2V5M1_HUMAN,tr|A0A7I2V5K3|A0A7I2V5K3_HUMAN,tr|A0A7I2V369|A0A7I2V369_HUMAN" 8 1388.6976 1.38 4425 16326 2 1388.694892 695.3561 "60 kDa heat shock protein, mitochondrial OS=Homo sapiens OX=9606 GN=HSPD1 PE=1 SV=2" 8.5 3307.6 - 494888 - - - -1.9623 - 2.137 0.571 - 409.2 1 2 0 -0.0027 12 0 0 0 2.94E+07 2.13E+07 - - - 5.2557 0.9995 221125_WJC_METTL3_EV_vs_WT_F01.16329.16329.2 0.024 16-Aug K.LLC[160.03]GLLAER.L sp|P14174|MIF_HUMAN 1 1043.5798 1.01 4427 16329 2 1043.578683 522.7972 Macrophage migration inhibitory factor OS=Homo sapiens OX=9606 GN=MIF PE=1 SV=4 5.99 3307.9 - 3.59E+06 - - - -1.0234 - 1.782 0.344 - 173.2 1 2 0 -0.0011 9 0 0 0 1.37E+08 1.36E+08 - - - 3.2529 0.9993 221125_WJC_METTL3_EV_vs_WT_F01.16332.16332.2 0.00178 14-Jul K.VFLENVIR.D sp|P62805|H4_HUMAN 1 988.5706 1.12 4430 16332 2 988.571596 495.2926 Histone H4 OS=Homo sapiens OX=9606 GN=H4C1 PE=1 SV=2 5.97 3308.1 - 3.63E+06 - - - 1.0419 - 1.561 0.356 - 180.7 1 2 0 0.001 8 0 0 0 5.27E+09 4.71E+09 - - - 3.0132 0.9919 221125_WJC_METTL3_EV_vs_WT_F01.16333.16333.2 6.04 12-Aug K.LDDLFLK[136.11].R "sp|P42704|LPPRC_HUMAN,tr|A0A804HI14|A0A804HI14_HUMAN,tr|A0A804HL40|A0A804HL40_HUMAN,tr|A0A804HKJ0|A0A804HKJ0_HUMAN,tr|A0A804HKR3|A0A804HKR3_HUMAN,tr|A0A804HIN4|A0A804HIN4_HUMAN,tr|A0A804HLG8|A0A804HLG8_HUMAN,tr|A0A804HHY9|A0A804HHY9_HUMAN,tr|A0A804HJZ1|A0A804HJZ1_HUMAN,tr|A0A804HK30|A0A804HK30_HUMAN,tr|A0A804HKI2|A0A804HKI2_HUMAN,tr|A0A804HIG4|A0A804HIG4_HUMAN" 12 870.4942 0.95 4431 16333 2 870.493624 436.2544 "Leucine-rich PPR motif-containing protein, mitochondrial OS=Homo sapiens OX=9606 GN=LRPPRC PE=1 SV=3" 4.21 3308.2 - 1.40E+06 - - - -0.6847 - 1.55 0.052 - 177.5 1 2 0 -0.0006 7 0 0 0 9.05E+07 9.56E+07 - - - 0.8135 1 221125_WJC_METTL3_EV_vs_WT_F01.16335.16335.2 4.93E-08 13/22 R.GYISPYFINTSK[136.11].G "sp|P10809|CH60_HUMAN,tr|A0A7I2V2X6|A0A7I2V2X6_HUMAN,tr|A0A7I2V599|A0A7I2V599_HUMAN,tr|A0A7I2YQ71|A0A7I2YQ71_HUMAN,tr|E7ESH4|E7ESH4_HUMAN,tr|A0A7I2V5M1|A0A7I2V5M1_HUMAN,tr|A0A7I2V5K3|A0A7I2V5K3_HUMAN,tr|A0A7I2V369|A0A7I2V369_HUMAN" 8 1396.7118 1.35 4433 16335 2 1396.71026 699.3632 "60 kDa heat shock protein, mitochondrial OS=Homo sapiens OX=9606 GN=HSPD1 PE=1 SV=2" 8.5 3308.5 - 926097 - - - -1.1148 - 2.314 0.643 - 511.3 1 2 0 -0.0016 12 0 0 0 2.84E+07 2.10E+07 - - - 5.9972 0.9857 221125_WJC_METTL3_EV_vs_WT_F01.16336.16336.2 0.193 16-Jun K.EAGAIISTR[166.11].H "sp|Q6ZUV0|BACHL_HUMAN,sp|O00154|BACH_HUMAN,tr|K7EKP8|K7EKP8_HUMAN" 3 926.5061 4.21 4434 16336 2 926.503775 464.2603 Putative cytosolic acyl coenzyme A thioester hydrolase-like OS=Homo sapiens OX=9606 GN=ACOT7L PE=5 SV=1 6.1 3308.6 - 712796 - - - -2.4717 - 1.162 0.225 - 71.6 1 2 0 -0.0023 9 0 0 0 3.00E+07 7.11E+06 - - - 1.1365 0.93 221125_WJC_METTL3_EV_vs_WT_F01.16337.16337.2 2.05 12-Aug K.LDDLFLK.R "sp|P42704|LPPRC_HUMAN,tr|A0A804HI14|A0A804HI14_HUMAN,tr|A0A804HL40|A0A804HL40_HUMAN,tr|A0A804HKJ0|A0A804HKJ0_HUMAN,tr|A0A804HKR3|A0A804HKR3_HUMAN,tr|A0A804HIN4|A0A804HIN4_HUMAN,tr|A0A804HLG8|A0A804HLG8_HUMAN,tr|A0A804HHY9|A0A804HHY9_HUMAN,tr|A0A804HJZ1|A0A804HJZ1_HUMAN,tr|A0A804HK30|A0A804HK30_HUMAN,tr|A0A804HKI2|A0A804HKI2_HUMAN,tr|A0A804HIG4|A0A804HIG4_HUMAN" 12 862.48 0.93 4435 16337 2 862.476011 432.2473 "Leucine-rich PPR motif-containing protein, mitochondrial OS=Homo sapiens OX=9606 GN=LRPPRC PE=1 SV=3" 4.21 3308.7 - 595227 - - - -4.6482 - 1.721 0.046 - 187.2 1 2 0 -0.004 7 0 0 0 8.91E+07 9.56E+07 - - - 1.0997 0.983 221125_WJC_METTL3_EV_vs_WT_F01.16339.16339.2 0.00061 16-Nov K.PLALVEEIR[166.11].N "sp|Q9BSD7|NTPCR_HUMAN,tr|Q5TDF0|Q5TDF0_HUMAN" 2 1048.6156 1.21 4437 16339 2 1048.613501 525.3151 Cancer-related nucleoside-triphosphatase OS=Homo sapiens OX=9606 GN=NTPCR PE=1 SV=1 4.53 3309 - 456411 - - - -2.0169 - 2.398 0.424 - 440 1 1 0 -0.0021 9 0 0 0 1.07E+07 8.85E+06 - - - 4.7024 0.9995 221125_WJC_METTL3_EV_vs_WT_F01.16343.16343.2 0.0098 14-Aug K.VFLENVIR[166.11].D sp|P62805|H4_HUMAN 1 998.5788 1.12 4439 16343 2 998.579968 500.2967 Histone H4 OS=Homo sapiens OX=9606 GN=H4C1 PE=1 SV=2 5.97 3309.5 - 1.82E+07 - - - 1.1336 - 1.755 0.372 - 285.2 1 2 0 0.0011 8 0 0 0 5.27E+09 4.71E+09 - - - 3.4846 0.9994 221125_WJC_METTL3_EV_vs_WT_F01.16345.16345.2 0.00114 16-Jun R.YVANLFPYK.G "sp|Q15181|IPYR_HUMAN,sp|Q9H2U2|IPYR2_HUMAN,tr|D6RGV9|D6RGV9_HUMAN,tr|Q5SQT6|Q5SQT6_HUMAN,tr|H0Y9D8|H0Y9D8_HUMAN,tr|D6RGI1|D6RGI1_HUMAN,tr|H0YAK2|H0YAK2_HUMAN" 7 1113.5859 0.46 4441 16345 2 1113.586642 557.8002 Inorganic pyrophosphatase OS=Homo sapiens OX=9606 GN=PPA1 PE=1 SV=2 8.5 3309.6 - 1.62E+06 - - - 0.6825 - 1.285 0.441 - 103.4 1 2 0 0.0008 9 0 0 0 3.10E+07 6.73E+07 - - - 3.0234 0.9988 221125_WJC_METTL3_EV_vs_WT_F01.16354.16354.2 0.167 12-Jul R.GFELTFK.T "sp|P39656|OST48_HUMAN,tr|U3KQ84|U3KQ84_HUMAN,tr|A0A0C4DGS1|A0A0C4DGS1_HUMAN" 3 840.4382 1.27 4448 16354 2 840.437399 421.2264 Dolichyl-diphosphooligosaccharide--protein glycosyltransferase 48 kDa subunit OS=Homo sapiens OX=9606 GN=DDOST PE=1 SV=4 6 3310.6 - 3.26E+06 - - - -0.8995 - 1.241 0.351 - 170.2 1 2 0 -0.0008 7 0 0 0 5.34E+07 4.21E+07 - - - 2.3174 0.9909 221125_WJC_METTL3_EV_vs_WT_F01.16358.16358.2 0.141 14-Jun K.YVVGLIIK[136.11].T "sp|O14980|XPO1_HUMAN,tr|A0A7I2V461|A0A7I2V461_HUMAN,tr|A0A7I2V2H0|A0A7I2V2H0_HUMAN,tr|A0A7I2V3N0|A0A7I2V3N0_HUMAN,tr|A0A7I2V4A3|A0A7I2V4A3_HUMAN,tr|C9J673|C9J673_HUMAN,tr|C9JKM9|C9JKM9_HUMAN,tr|A0A7I2V3W6|A0A7I2V3W6_HUMAN,tr|A0A7I2YQV4|A0A7I2YQV4_HUMAN,tr|A0A7I2YQX3|A0A7I2YQX3_HUMAN,tr|A0A7I2V2Y6|A0A7I2V2Y6_HUMAN,tr|A0A7I2V3P3|A0A7I2V3P3_HUMAN,tr|A0A7I2V2S3|A0A7I2V2S3_HUMAN" 13 911.5935 0.63 4452 16358 2 911.595504 456.804 Exportin-1 OS=Homo sapiens OX=9606 GN=XPO1 PE=1 SV=1 8.59 3311 - 529288 - - - 2.1545 - 1.021 0.304 - 96.8 1 2 0 0.002 8 0 0 0 1.72E+07 2.73E+07 - - - 1.3484 0.9997 221125_WJC_METTL3_EV_vs_WT_F01.16361.16361.2 0.0105 20-Oct K.ILITTVPPNLR.K "sp|Q12905|ILF2_HUMAN,tr|B4DY09|B4DY09_HUMAN" 2 1235.7602 1.23 4454 16361 2 1235.760638 618.8874 Interleukin enhancer-binding factor 2 OS=Homo sapiens OX=9606 GN=ILF2 PE=1 SV=2 9.75 3311.4 - 1.01E+06 - - - 0.3884 - 2.076 0.368 - 371.1 1 2 0 0.0005 11 0 0 0 6.09E+07 4.97E+07 - - - 3.7349 0.9998 221125_WJC_METTL3_EV_vs_WT_F01.16362.16362.2 0.000332 20-Oct K.ILITTVPPNLR[166.11].K "sp|Q12905|ILF2_HUMAN,tr|B4DY09|B4DY09_HUMAN" 2 1245.7684 1.23 4455 16362 2 1245.769125 623.8915 Interleukin enhancer-binding factor 2 OS=Homo sapiens OX=9606 GN=ILF2 PE=1 SV=2 9.75 3311.5 - 908379 - - - 0.5595 - 2.062 0.435 - 342.5 1 2 0 0.0007 11 0 0 0 6.09E+07 4.97E+07 - - - 4.2114 0.9983 221125_WJC_METTL3_EV_vs_WT_F01.16363.16363.2 0.0206 14-Aug R.LYEFYLSK[136.11].C "sp|Q5VZL5|ZMYM4_HUMAN,tr|H7C1I7|H7C1I7_HUMAN" 2 1069.5575 0.33 4456 16363 2 1069.55774 535.7861 Zinc finger MYM-type protein 4 OS=Homo sapiens OX=9606 GN=ZMYM4 PE=1 SV=1 6 3311.6 - 373052 - - - 0.1795 - 1.286 0.287 - 174.6 1 2 0 0.0002 8 0 0 0 4.95E+06 1.50E+07 - - - 1.9193 0.999 221125_WJC_METTL3_EV_vs_WT_F01.16365.16365.2 0.125 16-Aug R.LLVAVLTSR[166.11].A "sp|Q9P2E5|CHPF2_HUMAN,tr|G5E9W2|G5E9W2_HUMAN,tr|C9JZF7|C9JZF7_HUMAN" 3 980.6258 1.07 4458 16365 2 980.626463 491.3202 Chondroitin sulfate glucuronyltransferase OS=Homo sapiens OX=9606 GN=CHPF2 PE=2 SV=2 9.75 3311.9 - 210843 - - - 0.6904 - 1.696 0.256 - 153.5 1 2 0 0.0007 9 0 0 0 3.21E+06 3.01E+06 - - - 2.4599 0.9981 221125_WJC_METTL3_EV_vs_WT_F01.16371.16371.2 0.896 16-Sep K.R[166.11]VLGLVLLR[166.11].G "sp|P63162|RSMN_HUMAN,sp|P14678|RSMB_HUMAN,tr|J3QLE5|J3QLE5_HUMAN" 3 1057.7239 0.87 4462 16371 2 1057.721955 529.8692 Small nuclear ribonucleoprotein-associated protein N OS=Homo sapiens OX=9606 GN=SNRPN PE=1 SV=1 12 3312.6 - 1.01E+06 - - - -1.8143 - 1.484 0.298 - 129.8 1 2 0 -0.0019 9 0 0 0 1.44E+07 1.65E+07 - - - 2.3834 0.9502 221125_WJC_METTL3_EV_vs_WT_F01.16372.16372.2 6.77 12-Jun R.FLNVIER.H "sp|O94953|KDM4B_HUMAN,tr|A0A0C4DFL8|A0A0C4DFL8_HUMAN,tr|F5GX28|F5GX28_HUMAN,tr|K7EQ54|K7EQ54_HUMAN" 4 889.5022 0.88 4463 16372 2 889.501627 445.7584 Lysine-specific demethylase 4B OS=Homo sapiens OX=9606 GN=KDM4B PE=1 SV=4 6 3312.7 - 497244 - - - -0.5902 - 1.227 0.016 - 113.8 3 2 0 -0.0005 7 0 0 0 1.88E+07 2.15E+07 - - - -0.4059 0.999 221125_WJC_METTL3_EV_vs_WT_F01.16373.16373.2 0.0198 22-Sep R.VLIGNVQPGILR[166.11].F "sp|Q5VT06|CE350_HUMAN,tr|H0Y7F7|H0Y7F7_HUMAN" 2 1287.7902 2.2 4464 16373 2 1287.791961 644.9024 Centrosome-associated protein 350 OS=Homo sapiens OX=9606 GN=CEP350 PE=1 SV=1 9.72 3312.8 - 405133 - - - 1.3473 - 1.699 0.316 - 172 1 2 0 0.0017 12 0 0 0 2.41E+07 1.10E+07 - - - 2.7691 0.9994 221125_WJC_METTL3_EV_vs_WT_F01.16375.16375.2 1.17E-05 22-Oct K.LMDEVAGIVAAR[166.11].H "sp|O00154|BACH_HUMAN,tr|K7EKP8|K7EKP8_HUMAN" 2 1253.6677 0.79 4466 16375 2 1253.669668 627.8411 Cytosolic acyl coenzyme A thioester hydrolase OS=Homo sapiens OX=9606 GN=ACOT7 PE=1 SV=3 4.37 3313.1 - 144328 - - - 1.5475 - 2.183 0.315 - 353.7 1 2 0 0.0019 12 0 0 0 6.10E+06 7.69E+06 - - - 3.4211 0.9707 221125_WJC_METTL3_EV_vs_WT_F01.16378.16378.2 5.15 12-Jun R.VPFSLLR.G "sp|P04792|HSPB1_HUMAN,tr|A0A6Q8PGY2|A0A6Q8PGY2_HUMAN,tr|A0A6Q8PHJ6|A0A6Q8PHJ6_HUMAN,tr|A0A6Q8PHA6|A0A6Q8PHA6_HUMAN,tr|A0A6Q8PF43|A0A6Q8PF43_HUMAN,tr|A0A6Q8PFK8|A0A6Q8PFK8_HUMAN,tr|A0A6Q8PGK1|A0A6Q8PGK1_HUMAN,tr|A0A6Q8PH65|A0A6Q8PH65_HUMAN,tr|A0A6Q8PFE7|A0A6Q8PFE7_HUMAN" 9 830.5014 1.51 4467 16378 2 830.500115 416.258 Heat shock protein beta-1 OS=Homo sapiens OX=9606 GN=HSPB1 PE=1 SV=2 9.72 3313.5 - 1.99E+06 - - - -1.5762 - 1.115 0.113 - 151.9 1 2 0 -0.0013 7 0 0 0 1.91E+08 1.26E+08 - - - 0.2201 0.9943 221125_WJC_METTL3_EV_vs_WT_F01.16380.16380.2 0.881 12-Aug R.LLQLWEK[136.11].N "sp|Q8IWX8|CHERP_HUMAN,tr|J3QK89|J3QK89_HUMAN" 2 936.5524 1.42 4469 16380 2 936.555049 469.2835 Calcium homeostasis endoplasmic reticulum protein OS=Homo sapiens OX=9606 GN=CHERP PE=1 SV=3 6 3313.7 - 3.35E+06 - - - 2.8253 - 1.539 0.226 - 185 1 2 0 0.0026 7 0 0 0 7.34E+07 5.16E+07 - - - 2.0755 0.863 221125_WJC_METTL3_EV_vs_WT_F01.16381.16381.2 7.33 14-May K.YVVGLIIK.T "sp|O14980|XPO1_HUMAN,tr|A0A7I2V461|A0A7I2V461_HUMAN,tr|A0A7I2V2H0|A0A7I2V2H0_HUMAN,tr|A0A7I2V3N0|A0A7I2V3N0_HUMAN,tr|A0A7I2V4A3|A0A7I2V4A3_HUMAN,tr|C9J673|C9J673_HUMAN,tr|C9JKM9|C9JKM9_HUMAN,tr|A0A7I2V3W6|A0A7I2V3W6_HUMAN,tr|A0A7I2YQV4|A0A7I2YQV4_HUMAN,tr|A0A7I2YQX3|A0A7I2YQX3_HUMAN,tr|A0A7I2V2Y6|A0A7I2V2Y6_HUMAN,tr|A0A7I2V3P3|A0A7I2V3P3_HUMAN,tr|A0A7I2V2S3|A0A7I2V2S3_HUMAN" 13 903.5793 0.63 4470 16381 2 903.578596 452.7969 Exportin-1 OS=Homo sapiens OX=9606 GN=XPO1 PE=1 SV=1 8.59 3313.8 - 725018 - - - -0.8234 - 0.943 0.041 - 57.4 3 2 0 -0.0007 8 0 0 0 1.73E+07 2.75E+07 - - - -1.0465 0.9996 221125_WJC_METTL3_EV_vs_WT_F01.16382.16382.2 0.00799 14-Aug R.LMGDYLLR.G "sp|O60232|ZNRD2_HUMAN,tr|H0YEK1|H0YEK1_HUMAN,tr|E9PK41|E9PK41_HUMAN,tr|H0YEB6|H0YEB6_HUMAN" 4 979.5161 4.08 4471 16382 2 979.51572 490.7653 Protein ZNRD2 OS=Homo sapiens OX=9606 GN=ZNRD2 PE=1 SV=1 5.84 3313.9 - 483704 - - - -0.3757 - 1.436 0.435 - 180.1 1 2 0 -0.0004 8 0 0 0 6.97E+07 1.71E+07 - - - 3.3452 0.9987 221125_WJC_METTL3_EV_vs_WT_F01.16383.16383.2 0.0063 18-Aug R.LNYGIPAIVK.L sp|P14923|PLAK_HUMAN 1 1086.6437 180.12 4472 16383 2 1086.64169 544.3291 Junction plakoglobin OS=Homo sapiens OX=9606 GN=JUP PE=1 SV=3 8.59 3314.1 - 425509 - - - -1.8783 - 1.658 0.31 - 150.1 1 2 0 -0.002 10 0 0 0 3.41E+07 1.90E+05 - - - 2.7413 0.9694 221125_WJC_METTL3_EV_vs_WT_F01.16389.16389.2 0.0446 16-Aug R.EPGEFALLR.S sp|O43505|B4GA1_HUMAN 1 1030.5447 0.82 4476 16389 2 1030.53858 516.2796 "Beta-1,4-glucuronyltransferase 1 OS=Homo sapiens OX=9606 GN=B4GAT1 PE=1 SV=1" 4.53 3314.9 - 599597 - - - -5.9823 - 1.719 0.263 - 295.5 1 2 0 -0.0062 9 0 0 0 1.40E+08 1.72E+08 - - - 2.5489 0.9991 221125_WJC_METTL3_EV_vs_WT_F01.16391.16391.2 0.598 14-Sep K.VITLC[160.03]LYR[166.11].D sp|Q10570|CPSF1_HUMAN 1 1046.5822 0.44 4478 16391 2 1046.583172 524.2984 Cleavage and polyadenylation specificity factor subunit 1 OS=Homo sapiens OX=9606 GN=CPSF1 PE=1 SV=2 8.19 3315.1 - 459407 - - - 0.922 - 1.945 0.22 - 236.6 1 2 0 0.001 8 0 0 0 4.45E+06 1.02E+07 - - - 2.672 0.9994 221125_WJC_METTL3_EV_vs_WT_F01.16392.16392.2 0.0778 18-Sep K.ALFLETEQLK.K "sp|Q13740|CD166_HUMAN,tr|F5GXJ9|F5GXJ9_HUMAN" 2 1190.6547 1.18 4479 16392 2 1190.653832 596.3346 CD166 antigen OS=Homo sapiens OX=9606 GN=ALCAM PE=1 SV=2 4.53 3315.2 - 336046 - - - -0.7206 - 1.809 0.303 - 251.5 1 2 0 -0.0009 10 0 0 0 3.79E+06 3.22E+06 - - - 2.9333 0.9952 221125_WJC_METTL3_EV_vs_WT_F01.16394.16394.2 0.0204 14-Sep R.VDEIIWVK[136.11].T sp|Q86U44|MTA70_HUMAN 1 1008.5735 0.01 4480 16394 2 1008.569445 505.294 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 4.37 3315.5 - 7.19E+07 - - - -4.0532 - 2.016 0.253 - 266 1 2 0 -0.0041 8 0 0 0 2.71E+07 3.83E+09 - - - 3.0229 0.9917 221125_WJC_METTL3_EV_vs_WT_F01.16398.16398.2 0.187 12-Aug R.VPFSLLR[166.11].G "sp|P04792|HSPB1_HUMAN,tr|A0A6Q8PGY2|A0A6Q8PGY2_HUMAN,tr|A0A6Q8PHJ6|A0A6Q8PHJ6_HUMAN,tr|A0A6Q8PHA6|A0A6Q8PHA6_HUMAN,tr|A0A6Q8PF43|A0A6Q8PF43_HUMAN,tr|A0A6Q8PFK8|A0A6Q8PFK8_HUMAN,tr|A0A6Q8PGK1|A0A6Q8PGK1_HUMAN,tr|A0A6Q8PH65|A0A6Q8PH65_HUMAN,tr|A0A6Q8PFE7|A0A6Q8PFE7_HUMAN" 9 840.5097 1.51 4483 16398 2 840.508408 421.2621 Heat shock protein beta-1 OS=Homo sapiens OX=9606 GN=HSPB1 PE=1 SV=2 9.72 3315.9 - 3.53E+06 - - - -1.53 - 1.253 0.177 - 268.5 1 2 0 -0.0013 7 0 0 0 1.91E+08 1.26E+08 - - - 1.0626 0.9971 221125_WJC_METTL3_EV_vs_WT_F01.16399.16399.2 0.0621 14-Jun R.VLFLSTVR[166.11].T "sp|P42694|HELZ_HUMAN,tr|J3QS41|J3QS41_HUMAN" 2 943.573 1.78 4484 16399 2 943.571726 472.7938 Probable helicase with zinc finger domain OS=Homo sapiens OX=9606 GN=HELZ PE=1 SV=2 9.72 3315.9 - 2.01E+06 - - - -1.3746 - 1.43 0.224 - 101.9 1 2 0 -0.0013 8 0 0 0 8.70E+07 4.89E+07 - - - 1.7738 0.9997 221125_WJC_METTL3_EV_vs_WT_F01.16405.16405.2 0.00242 14-Sep R.VLFLSTVR.T "sp|P42694|HELZ_HUMAN,tr|J3QS41|J3QS41_HUMAN" 2 933.5648 1.78 4488 16405 2 933.563854 467.7897 Probable helicase with zinc finger domain OS=Homo sapiens OX=9606 GN=HELZ PE=1 SV=2 9.72 3316.7 - 3.94E+06 - - - -0.963 - 1.828 0.41 - 310 1 2 0 -0.0009 8 0 0 0 8.71E+07 4.90E+07 - - - 3.8883 0.9998 221125_WJC_METTL3_EV_vs_WT_F01.16406.16406.2 0.0006 16-Aug R.ATLNAFLYR[166.11].T "sp|Q5T2N8|ATD3C_HUMAN,sp|Q9NVI7|ATD3A_HUMAN,tr|Q5SV16|Q5SV16_HUMAN" 3 1077.5847 1.08 4489 16406 2 1077.584116 539.7996 ATPase family AAA domain-containing protein 3C OS=Homo sapiens OX=9606 GN=ATAD3C PE=2 SV=2 8.79 3316.9 - 1.21E+06 - - - -0.4956 - 1.928 0.412 - 228.6 1 2 0 -0.0005 9 0 0 0 6.86E+07 6.36E+07 - - - 3.9831 0.9995 221125_WJC_METTL3_EV_vs_WT_F01.16407.16407.2 0.000129 18-Oct R.FVNVVPTFGK[136.11].K "sp|P62861|RS30_HUMAN,tr|E9PR30|E9PR30_HUMAN" 2 1114.6266 0.46 4490 16407 2 1114.626576 558.3206 40S ribosomal protein S30 OS=Homo sapiens OX=9606 GN=FAU PE=1 SV=1 8.75 3316.9 - 1.45E+06 - - - -0.0493 - 1.89 0.3 - 287.1 1 2 0 -0.0001 10 0 0 0 2.37E+07 5.11E+07 - - - 3.0337 0.9997 221125_WJC_METTL3_EV_vs_WT_F01.16408.16408.2 0.0013 16-Sep R.ATLNAFLYR.T "sp|Q5T2N8|ATD3C_HUMAN,sp|Q9NVI7|ATD3A_HUMAN,tr|Q5SV16|Q5SV16_HUMAN" 3 1067.5764 1.08 4491 16408 2 1067.575463 534.7955 ATPase family AAA domain-containing protein 3C OS=Homo sapiens OX=9606 GN=ATAD3C PE=2 SV=2 8.79 3317 - 1.12E+06 - - - -0.859 - 2.017 0.39 - 254.9 1 2 0 -0.0009 9 0 0 0 6.86E+07 6.36E+07 - - - 3.9511 0.9998 221125_WJC_METTL3_EV_vs_WT_F01.16409.16409.2 0.00011 18-Oct K.IVAFENAFER[166.11].L sp|O60763|USO1_HUMAN 1 1204.6116 0.52 4492 16409 2 1204.610853 603.3131 General vesicular transport factor p115 OS=Homo sapiens OX=9606 GN=USO1 PE=1 SV=2 4.53 3317.2 - 946344 - - - -0.6143 - 1.787 0.438 - 314 1 2 0 -0.0007 10 0 0 0 1.05E+07 2.02E+07 - - - 3.8963 0.9999 221125_WJC_METTL3_EV_vs_WT_F01.16411.16411.2 1.63E-06 24-Oct R.MVIITGPPEAQFK.A "sp|Q9NZI8|IF2B1_HUMAN,sp|O00425|IF2B3_HUMAN,sp|Q9Y6M1|IF2B2_HUMAN,tr|F8W930|F8W930_HUMAN" 4 1429.7639 1.95 4494 16411 2 1429.763413 715.8892 Insulin-like growth factor 2 mRNA-binding protein 1 OS=Homo sapiens OX=9606 GN=IGF2BP1 PE=1 SV=2 5.75 3317.4 - 327337 - - - -0.3567 - 2.187 0.616 - 283.8 1 2 0 -0.0005 13 0 0 0 8.00E+06 4.09E+06 - - - 5.599 0.9996 221125_WJC_METTL3_EV_vs_WT_F01.16414.16414.2 0.0012 18-Sep R.FVNVVPTFGK.K "sp|P62861|RS30_HUMAN,tr|E9PR30|E9PR30_HUMAN" 2 1106.6124 0.46 4495 16414 2 1106.612979 554.3135 40S ribosomal protein S30 OS=Homo sapiens OX=9606 GN=FAU PE=1 SV=1 8.75 3317.8 - 767197 - - - 0.4952 - 1.586 0.392 - 225.7 1 2 0 0.0005 10 0 0 0 2.37E+07 5.10E+07 - - - 3.2235 0.9967 221125_WJC_METTL3_EV_vs_WT_F01.16416.16416.2 0.162 14-Aug R.ILELDQFK[136.11].G "sp|P12956|XRCC6_HUMAN,tr|B1AHC9|B1AHC9_HUMAN" 2 1012.5684 0.96 4496 16416 2 1012.564406 507.2915 X-ray repair cross-complementing protein 6 OS=Homo sapiens OX=9606 GN=XRCC6 PE=1 SV=2 4.37 3318 - 1.79E+07 - - - -3.9908 - 1.86 0.335 - 167.7 1 2 0 -0.004 8 0 0 0 3.45E+08 3.59E+08 - - - 3.3857 0.9978 221125_WJC_METTL3_EV_vs_WT_F01.16417.16417.2 0.152 13/22 R.VLIGNVQPGILR.F "sp|Q5VT06|CE350_HUMAN,tr|H0Y7F7|H0Y7F7_HUMAN" 2 1277.782 2.2 4497 16417 2 1277.781189 639.8983 Centrosome-associated protein 350 OS=Homo sapiens OX=9606 GN=CEP350 PE=1 SV=1 9.72 3318.2 - 1.23E+06 - - - -0.6003 - 1.75 0.168 - 188.7 1 2 0 -0.0008 12 0 0 0 2.41E+07 1.10E+07 - - - 1.7541 0.9976 221125_WJC_METTL3_EV_vs_WT_F01.16418.16418.2 0.611 12-Aug R.IQLIFER.A "sp|Q15020|SART3_HUMAN,tr|A0A499FI31|A0A499FI31_HUMAN" 2 917.5335 1.5 4498 16418 2 917.532332 459.774 Squamous cell carcinoma antigen recognized by T-cells 3 OS=Homo sapiens OX=9606 GN=SART3 PE=1 SV=1 6 3318.2 - 4.23E+06 - - - -1.2207 - 1.756 0.141 - 238 1 2 0 -0.0011 7 0 0 0 9.26E+07 6.18E+07 - - - 1.8661 0.9977 221125_WJC_METTL3_EV_vs_WT_F01.16420.16420.2 0.0479 14-Jun R.VFPMPLPR[166.11].K "sp|Q15003|CND2_HUMAN,tr|C9J470|C9J470_HUMAN,tr|C9JZP1|C9JZP1_HUMAN,tr|E9PHA2|E9PHA2_HUMAN" 4 965.5396 1.66 4500 16420 2 965.540372 483.7771 Condensin complex subunit 2 OS=Homo sapiens OX=9606 GN=NCAPH PE=1 SV=3 9.72 3318.4 - 826158 - - - 0.7851 - 1.287 0.274 - 143.9 1 2 0 0.0008 8 0 0 0 6.01E+07 3.63E+07 - - - 1.8255 0.8668 221125_WJC_METTL3_EV_vs_WT_F01.16425.16425.2 0.0216 16-Jul R.LSPFMADIR[166.11].D "sp|P21333|FLNA_HUMAN,tr|A0A7P0NMY4|A0A7P0NMY4_HUMAN,tr|Q60FE5|Q60FE5_HUMAN" 3 1058.5458 0.44 4503 16425 2 1058.536836 530.2802 Filamin-A OS=Homo sapiens OX=9606 GN=FLNA PE=1 SV=4 5.84 3319 - 1.11E+06 - - - -8.489 - 1.47 0.299 - 187.6 1 2 0 -0.009 9 0 0 0 3.79E+07 8.54E+07 - - - 2.3612 0.9997 221125_WJC_METTL3_EV_vs_WT_F01.16426.16426.2 0.00961 16-Sep R.LSPFMADIR.D "sp|P21333|FLNA_HUMAN,tr|A0A7P0NMY4|A0A7P0NMY4_HUMAN,tr|Q60FE5|Q60FE5_HUMAN" 3 1048.5376 0.45 4504 16426 2 1048.536892 525.2761 Filamin-A OS=Homo sapiens OX=9606 GN=FLNA PE=1 SV=4 5.84 3319.2 - 699201 - - - -0.6294 - 1.643 0.408 - 307 1 2 0 -0.0007 9 0 0 0 3.82E+07 8.42E+07 - - - 3.4908 0.7968 221125_WJC_METTL3_EV_vs_WT_F01.16431.16431.2 0.036 18-Jun D.VDEATGAVKK[136.11].H sp|Q96ST3|SIN3A_HUMAN 1 1024.5644 - 4508 16431 2 1024.566185 513.2895 Paired amphipathic helix protein Sin3a OS=Homo sapiens OX=9606 GN=SIN3A PE=1 SV=2 6.04 3319.6 - 3.76E+06 - - - 1.7178 - 1.432 0.228 - 79.4 1 1 0 0.0018 10 0 0 0 - - - - - 1.7267 0.7796 221125_WJC_METTL3_EV_vs_WT_F01.16432.16432.2 0.104 22-Jul R.MPGSVIPPPLVR[166.11].G sp|Q86YP4|P66A_HUMAN 1 1271.7299 1.64 4509 16432 2 1271.721558 636.8722 Transcriptional repressor p66-alpha OS=Homo sapiens OX=9606 GN=GATAD2A PE=1 SV=1 9.5 3319.8 - 289124 - - - -6.5863 - 1.257 0.201 - 92.2 1 2 0 -0.0084 12 0 0 0 8.27E+06 5.04E+06 - - - 1.1248 0.9629 221125_WJC_METTL3_EV_vs_WT_F01.16436.16436.2 2.77 12-Jun K.SIVAFLK[136.11].D "sp|Q14554|PDIA5_HUMAN,tr|C9JY10|C9JY10_HUMAN" 2 784.4938 0.59 4513 16436 2 784.492332 393.2542 Protein disulfide-isomerase A5 OS=Homo sapiens OX=9606 GN=PDIA5 PE=1 SV=1 8.47 3320.3 - 187469 - - - -1.9044 - 1.189 0.083 - 100.2 1 2 0 -0.0015 7 0 0 0 2.20E+06 3.70E+06 - - - 0.2021 0.9419 221125_WJC_METTL3_EV_vs_WT_F01.16439.16439.2 3.39 14-Jun K.LPLDVLGR.V "sp|Q9UBC2|EP15R_HUMAN,tr|M0R2S2|M0R2S2_HUMAN,tr|M0R165|M0R165_HUMAN" 3 881.5335 2.13 4514 16439 2 881.532618 441.774 Epidermal growth factor receptor substrate 15-like 1 OS=Homo sapiens OX=9606 GN=EPS15L1 PE=1 SV=1 5.84 3320.7 - 1.82E+06 - - - -0.9461 - 1.228 0.029 - 107.2 5 2 0 -0.0008 8 0 0 0 5.79E+07 2.72E+07 - - - -0.4379 0.8092 221125_WJC_METTL3_EV_vs_WT_F01.16441.16441.2 0.696 18-Jul R.EALEEETVAR.A "sp|Q9H5N1|RABE2_HUMAN,tr|B4DHR0|B4DHR0_HUMAN" 2 1145.5564 0.13 4516 16441 2 1145.551903 573.7855 Rab GTPase-binding effector protein 2 OS=Homo sapiens OX=9606 GN=RABEP2 PE=1 SV=2 4.09 3321 - 360449 - - - -3.9535 - 1.412 0.018 - 100.6 2 2 0 -0.0045 10 0 0 0 9.61E+06 7.61E+07 - - - 0.0011 0.9973 221125_WJC_METTL3_EV_vs_WT_F01.16444.16444.2 0.0354 18-Jun K.AVYTLTSLYR.Q "sp|Q9NR28|DBLOH_HUMAN,tr|H7BZQ7|H7BZQ7_HUMAN,tr|A0A2U3TZH2|A0A2U3TZH2_HUMAN,tr|A0A024RBT2|A0A024RBT2_HUMAN,tr|H7BZK7|H7BZK7_HUMAN" 5 1185.6394 1.81 4517 16444 2 1185.63804 593.827 "Diablo homolog, mitochondrial OS=Homo sapiens OX=9606 GN=DIABLO PE=1 SV=1" 8.63 3321.4 - 347753 - - - -1.1251 - 1.295 0.268 - 120 1 2 0 -0.0013 10 0 0 0 9.56E+06 5.27E+06 - - - 1.7416 0.9991 221125_WJC_METTL3_EV_vs_WT_F01.16449.16449.2 0.0276 12-Jul K.TDFGIFR[166.11].M "sp|Q9HCC0|MCCB_HUMAN,tr|A0A804HJC1|A0A804HJC1_HUMAN,tr|A0A804HK37|A0A804HK37_HUMAN,tr|A0A804HJ24|A0A804HJ24_HUMAN,tr|A0A804HL02|A0A804HL02_HUMAN,tr|A0A804HKE8|A0A804HKE8_HUMAN,tr|A0A804HJ84|A0A804HJ84_HUMAN,tr|A0A804HLJ9|A0A804HLJ9_HUMAN,tr|A0A804HJL2|A0A804HJL2_HUMAN,tr|A0A804HJ31|A0A804HJ31_HUMAN" 10 864.4369 0.85 4520 16449 2 864.436852 433.2257 "Methylcrotonoyl-CoA carboxylase beta chain, mitochondrial OS=Homo sapiens OX=9606 GN=MCCC2 PE=1 SV=1" 5.5 3322 - 806820 - - - -0.0821 - 1.546 0.27 - 195.8 1 2 0 -0.0001 7 0 0 0 1.60E+07 1.88E+07 - - - 2.4156 0.8798 221125_WJC_METTL3_EV_vs_WT_F01.16450.16450.2 0.0238 16-May R.LVNHFVEEF.K "sp|P0DMV8|HS71A_HUMAN,sp|P0DMV9|HS71B_HUMAN,tr|V9GZ37|V9GZ37_HUMAN,tr|A0A0G2JIW1|A0A0G2JIW1_HUMAN" 4 1132.5553 - 4521 16450 2 1132.554147 567.2849 Heat shock 70 kDa protein 1A OS=Homo sapiens OX=9606 GN=HSPA1A PE=1 SV=1 4.51 3322.1 - 670152 - - - -1.0269 - 1.198 0.327 - 57.3 2 1 0 -0.0012 9 0 0 0 - - - - - 1.844 0.9983 221125_WJC_METTL3_EV_vs_WT_F01.16457.16457.2 0.192 14-Jul R.VWDISGLR.K "sp|P53621|COPA_HUMAN,tr|A0A3B3ISC6|A0A3B3ISC6_HUMAN,tr|A0A3B3ITV3|A0A3B3ITV3_HUMAN,tr|A0A3B3IU78|A0A3B3IU78_HUMAN,tr|A0A3B3IS84|A0A3B3IS84_HUMAN,tr|A0A3B3ISK1|A0A3B3ISK1_HUMAN,tr|A0A3B3IT15|A0A3B3IT15_HUMAN" 7 944.508 0.19 4526 16457 2 944.508706 473.2613 Coatomer subunit alpha OS=Homo sapiens OX=9606 GN=COPA PE=1 SV=2 5.81 3322.9 - 880934 - - - 0.7835 - 1.615 0.218 - 157.2 1 2 0 0.0007 8 0 0 0 1.49E+07 7.93E+07 - - - 2.0966 0.9981 221125_WJC_METTL3_EV_vs_WT_F01.16462.16462.2 0.0322 16-Jun K.LFSELPLAK[136.11].K "sp|Q9Y291|RT33_HUMAN,tr|C9JBY7|C9JBY7_HUMAN" 2 1024.6048 1.19 4529 16462 2 1024.604969 513.3097 "28S ribosomal protein S33, mitochondrial OS=Homo sapiens OX=9606 GN=MRPS33 PE=1 SV=1" 6 3323.5 - 3.13E+06 - - - 0.1327 - 1.247 0.29 - 93.2 1 2 0 0.0001 9 0 0 0 1.37E+08 1.15E+08 - - - 1.8215 0.9916 221125_WJC_METTL3_EV_vs_WT_F01.16463.16463.2 0.0819 12-Jul K.TDFGIFR.M "sp|Q9HCC0|MCCB_HUMAN,tr|A0A804HJC1|A0A804HJC1_HUMAN,tr|A0A804HK37|A0A804HK37_HUMAN,tr|A0A804HJ24|A0A804HJ24_HUMAN,tr|A0A804HL02|A0A804HL02_HUMAN,tr|A0A804HKE8|A0A804HKE8_HUMAN,tr|A0A804HJ84|A0A804HJ84_HUMAN,tr|A0A804HLJ9|A0A804HLJ9_HUMAN,tr|A0A804HJL2|A0A804HJL2_HUMAN,tr|A0A804HJ31|A0A804HJ31_HUMAN" 10 854.4287 0.85 4530 16463 2 854.42824 428.2216 "Methylcrotonoyl-CoA carboxylase beta chain, mitochondrial OS=Homo sapiens OX=9606 GN=MCCC2 PE=1 SV=1" 5.5 3323.7 - 1.02E+06 - - - -0.4834 - 1.191 0.157 - 215.4 1 2 0 -0.0004 7 0 0 0 1.60E+07 1.88E+07 - - - 0.7543 0.9995 221125_WJC_METTL3_EV_vs_WT_F01.16464.16464.2 0.0933 18-Nov R.LLLNNDNLLR[166.11].E "sp|P52907|CAZA1_HUMAN,sp|P47755|CAZA2_HUMAN,tr|C9JUG7|C9JUG7_HUMAN,tr|A0A0D9SET8|A0A0D9SET8_HUMAN,tr|F8W9N7|F8W9N7_HUMAN" 5 1206.696 1.06 4531 16464 2 1206.698258 604.3553 F-actin-capping protein subunit alpha-1 OS=Homo sapiens OX=9606 GN=CAPZA1 PE=1 SV=3 5.84 3323.8 - 688694 - - - 1.8787 - 2.255 0.352 - 386.1 1 2 0 0.0023 10 0 0 0 1.66E+08 1.58E+08 - - - 3.9099 0.9998 221125_WJC_METTL3_EV_vs_WT_F01.16470.16470.2 0.0002 12-Aug R.YGDFFIR.Q "sp|Q9Y262|EIF3L_HUMAN,tr|B0QY89|B0QY89_HUMAN,tr|H0Y7E6|H0Y7E6_HUMAN,tr|B0QY90|B0QY90_HUMAN" 4 916.4443 1.05 4535 16470 2 916.44462 459.2294 Eukaryotic translation initiation factor 3 subunit L OS=Homo sapiens OX=9606 GN=EIF3L PE=1 SV=1 5.84 3324.5 - 1.73E+06 - - - 0.3459 - 1.766 0.453 - 219.3 1 2 0 0.0003 7 0 0 0 3.15E+07 2.99E+07 - - - 4.1888 0.9997 221125_WJC_METTL3_EV_vs_WT_F01.16471.16471.2 0.00231 16-Sep K.LFSELPLAK.K "sp|Q9Y291|RT33_HUMAN,tr|C9JBY7|C9JBY7_HUMAN" 2 1016.5906 1.18 4536 16471 2 1016.591074 509.3026 "28S ribosomal protein S33, mitochondrial OS=Homo sapiens OX=9606 GN=MRPS33 PE=1 SV=1" 6 3324.6 - 4.62E+06 - - - 0.4338 - 1.643 0.447 - 247.1 1 2 0 0.0004 9 0 0 0 1.40E+08 1.19E+08 - - - 3.7789 0.9962 221125_WJC_METTL3_EV_vs_WT_F01.16472.16472.2 8.60E-05 12-Aug R.YGDFFIR[166.11].Q "sp|Q9Y262|EIF3L_HUMAN,tr|B0QY89|B0QY89_HUMAN,tr|H0Y7E6|H0Y7E6_HUMAN,tr|B0QY90|B0QY90_HUMAN" 4 926.4526 1.06 4537 16472 2 926.457154 464.2336 Eukaryotic translation initiation factor 3 subunit L OS=Homo sapiens OX=9606 GN=EIF3L PE=1 SV=1 5.84 3324.6 - 1.94E+06 - - - 4.9447 - 1.597 0.48 - 201.8 1 2 0 0.0046 7 0 0 0 3.16E+07 2.99E+07 - - - 4.0681 0.9998 221125_WJC_METTL3_EV_vs_WT_F01.16473.16473.2 0.0346 20-Oct R.ALAAQLPVLPR.S "sp|Q96GK7|FAH2A_HUMAN,tr|C9JGM0|C9JGM0_HUMAN" 2 1147.7077 1.6 4538 16473 2 1147.70856 574.8611 Fumarylacetoacetate hydrolase domain-containing protein 2A OS=Homo sapiens OX=9606 GN=FAHD2A PE=1 SV=1 9.79 3324.8 - 508367 - - - 0.7249 - 2.454 0.403 - 272.7 1 2 0 0.0008 11 0 0 0 1.47E+07 9.18E+06 - - - 4.4458 0.8669 221125_WJC_METTL3_EV_vs_WT_F01.16474.16474.2 4 12-May K.LFNPLIR.L sp|Q9Y5B6|PAXB1_HUMAN 1 871.528 0.11 4539 16474 2 871.528738 436.7713 PAX3- and PAX7-binding protein 1 OS=Homo sapiens OX=9606 GN=PAXBP1 PE=1 SV=2 9.75 3324.9 - 350714 - - - 0.8778 - 1.102 0.026 - 63.2 13 2 0 0.0008 7 0 0 0 6.49E+06 5.73E+07 - - - -0.9571 0.9992 221125_WJC_METTL3_EV_vs_WT_F01.16478.16478.2 0.0106 18-Oct R.LLLNNDNLLR.E "sp|P52907|CAZA1_HUMAN,sp|P47755|CAZA2_HUMAN,tr|C9JUG7|C9JUG7_HUMAN,tr|A0A0D9SET8|A0A0D9SET8_HUMAN,tr|F8W9N7|F8W9N7_HUMAN" 5 1196.6877 1.03 4541 16478 2 1196.691528 599.3511 F-actin-capping protein subunit alpha-1 OS=Homo sapiens OX=9606 GN=CAPZA1 PE=1 SV=3 5.84 3325.5 - 1.39E+06 - - - 3.1813 - 2.268 0.429 - 311.7 1 2 0 0.0038 10 0 0 0 1.67E+08 1.62E+08 - - - 4.4942 0.9984 221125_WJC_METTL3_EV_vs_WT_F01.16479.16479.2 0.0394 18-Aug R.VIAIDIDPVK.L sp|Q96RS0|TGS1_HUMAN 1 1081.6383 1.3 4542 16479 2 1081.639405 541.8264 Trimethylguanosine synthase OS=Homo sapiens OX=9606 GN=TGS1 PE=1 SV=3 4.21 3325.5 - 991625 - - - 1.0114 - 1.725 0.222 - 195.1 1 2 0 0.0011 10 0 0 0 2.12E+07 1.63E+07 - - - 2.2022 0.9999 221125_WJC_METTL3_EV_vs_WT_F01.16480.16480.2 3.78E-05 14/20 R.ALDEGDIALLK[136.11].T "sp|P35998|PRS7_HUMAN,tr|C9JX88|C9JX88_HUMAN,tr|C9JLS9|C9JLS9_HUMAN" 3 1164.6482 0.99 4543 16480 2 1164.648873 583.3314 26S proteasome regulatory subunit 7 OS=Homo sapiens OX=9606 GN=PSMC2 PE=1 SV=3 4.03 3325.6 - 627439 - - - 0.6174 - 2.7 0.534 - 533.6 1 2 0 0.0007 11 0 0 0 2.04E+07 2.06E+07 - - - 5.6719 0.9492 221125_WJC_METTL3_EV_vs_WT_F01.16490.16490.2 0.274 14-Jul R.LELSVLYK[136.11].E "sp|Q96FW1|OTUB1_HUMAN,tr|F5GYN4|F5GYN4_HUMAN,tr|F5GYJ8|F5GYJ8_HUMAN,tr|J3KR44|J3KR44_HUMAN,tr|F5H6Q1|F5H6Q1_HUMAN" 5 971.5783 1.62 4551 16490 2 971.582457 486.7964 Ubiquitin thioesterase OTUB1 OS=Homo sapiens OX=9606 GN=OTUB1 PE=1 SV=2 6 3326.9 - 477950 - - - 4.2951 - 1.476 0.131 - 124.2 1 2 0 0.0042 8 0 0 0 1.16E+07 7.13E+06 - - - 1.1815 0.9991 221125_WJC_METTL3_EV_vs_WT_F01.16492.16492.2 0.213 20-Oct K.IILEAALQAAK.S sp|Q08378|GOGA3_HUMAN 1 1139.6914 0.42 4553 16492 2 1139.694109 570.853 Golgin subfamily A member 3 OS=Homo sapiens OX=9606 GN=GOLGA3 PE=1 SV=2 6 3327.2 - 273157 - - - 2.3682 - 1.725 0.406 - 207.2 1 2 0 0.0027 11 0 0 0 5.81E+06 1.39E+07 - - - 3.5138 0.9996 221125_WJC_METTL3_EV_vs_WT_F01.16504.16504.2 0.00482 18-Sep K.ILETTTFFQR[166.11].A sp|Q9NYU2|UGGG1_HUMAN 1 1264.6691 3.17 4563 16504 2 1264.671383 633.3418 UDP-glucose:glycoprotein glucosyltransferase 1 OS=Homo sapiens OX=9606 GN=UGGT1 PE=1 SV=3 6 3328.7 - 237115 - - - 1.7989 - 1.917 0.465 - 321.1 1 2 0 0.0023 10 0 0 0 1.34E+07 4.22E+06 - - - 4.2912 0.9984 221125_WJC_METTL3_EV_vs_WT_F01.16505.16505.2 0.293 22-Aug R.VLPAPILQYGGR.N "sp|Q9UL18|AGO1_HUMAN,tr|A0A6I8PTZ8|A0A6I8PTZ8_HUMAN,tr|Q5TA58|Q5TA58_HUMAN" 3 1282.7398 2.39 4564 16505 2 1282.741449 642.3772 Protein argonaute-1 OS=Homo sapiens OX=9606 GN=AGO1 PE=1 SV=3 8.72 3328.9 - 198259 - - - 1.3191 - 1.698 0.26 - 186.6 1 2 0 0.0017 12 0 0 0 4.05E+06 1.69E+06 - - - 2.3539 0.9915 221125_WJC_METTL3_EV_vs_WT_F01.16506.16506.2 0.00119 20-Sep R.LYPEGLAQLAR.A "sp|P61421|VA0D1_HUMAN,tr|J3QL14|J3QL14_HUMAN,tr|F5GYQ1|F5GYQ1_HUMAN,tr|R4GN72|R4GN72_HUMAN" 4 1229.6768 1.28 4565 16506 2 1229.682184 615.8457 V-type proton ATPase subunit d 1 OS=Homo sapiens OX=9606 GN=ATP6V0D1 PE=1 SV=1 6 3329 - 192881 - - - 4.3605 - 1.533 0.341 - 232.4 1 2 0 0.0054 11 0 0 0 1.52E+07 1.19E+07 - - - 2.7137 0.9994 221125_WJC_METTL3_EV_vs_WT_F01.16516.16516.2 0.00134 18-Sep K.VFEVMLATDR[166.11].S "sp|P22061|PIMT_HUMAN,tr|F6S8N6|F6S8N6_HUMAN,tr|F8WAV5|F8WAV5_HUMAN,tr|A0A0A0MRJ6|A0A0A0MRJ6_HUMAN,tr|F8WDT3|F8WDT3_HUMAN,tr|F8WAX2|F8WAX2_HUMAN" 6 1189.6041 0.74 4573 16516 2 1189.605183 595.8093 Protein-L-isoaspartate(D-aspartate) O-methyltransferase OS=Homo sapiens OX=9606 GN=PCMT1 PE=1 SV=4 4.37 3330.2 - 166727 - - - 0.9398 - 2.078 0.284 - 291.4 1 2 0 0.0011 10 0 0 0 6.73E+06 9.05E+06 - - - 3.1798 0.9915 221125_WJC_METTL3_EV_vs_WT_F01.16520.16520.2 4.44 14-Aug R.DILLQGLK[136.11].A "sp|Q99986|VRK1_HUMAN,tr|A0A7P0T838|A0A7P0T838_HUMAN,tr|H0YJJ9|H0YJJ9_HUMAN,tr|A0A7P0TA16|A0A7P0TA16_HUMAN,tr|A0A7P0T8N0|A0A7P0T8N0_HUMAN,tr|H0YJF7|H0YJF7_HUMAN,tr|A0A7P0T9T1|A0A7P0T9T1_HUMAN,tr|A0A7P0Z445|A0A7P0Z445_HUMAN,tr|A0A7P0TAA6|A0A7P0TAA6_HUMAN,tr|A0A7P0T9E5|A0A7P0T9E5_HUMAN,tr|A0A7P0TBB8|A0A7P0TBB8_HUMAN,tr|A0A7P0Z462|A0A7P0Z462_HUMAN,tr|A0A7P0TBE4|A0A7P0TBE4_HUMAN,tr|A0A7P0T925|A0A7P0T925_HUMAN,tr|H0YJ50|H0YJ50_HUMAN,tr|A0A7P0TA65|A0A7P0TA65_HUMAN,tr|A0A7P0T824|A0A7P0T824_HUMAN,tr|A0A7P0T9I1|A0A7P0T9I1_HUMAN,tr|A0A7P0T977|A0A7P0T977_HUMAN,tr|A0A7P0Z3Z7|A0A7P0Z3Z7_HUMAN,tr|A0A7P0TAS8|A0A7P0TAS8_HUMAN,tr|A0A7P0TB15|A0A7P0TB15_HUMAN,tr|A0A7P0T952|A0A7P0T952_HUMAN" 23 906.563 0.07 4575 16520 2 906.56418 454.2888 Serine\threonine-protein kinase VRK1 OS=Homo sapiens OX=9606 GN=VRK1 PE=1 SV=1 5.84 3330.7 - 2.35E+06 - - - 1.3369 - 1.608 0.077 - 201.1 1 2 0 0.0012 8 0 0 0 2.36E+06 3.20E+07 - - - 1.0419 0.9996 221125_WJC_METTL3_EV_vs_WT_F01.16522.16522.2 0.035 13/18 R.ALEAELAALR[166.11].Q sp|Q16352|AINX_HUMAN 1 1065.6058 1.59 4577 16522 2 1065.606939 533.8102 Alpha-internexin OS=Homo sapiens OX=9606 GN=INA PE=1 SV=2 4.53 3330.9 - 1.00E+06 - - - 1.0886 - 2.375 0.305 - 754.2 1 2 0 0.0012 10 0 0 0 5.46E+07 3.44E+07 - - - 3.7078 0.9994 221125_WJC_METTL3_EV_vs_WT_F01.16531.16531.2 0.0037 18-Sep K.AVFVPDIYSR[166.11].T sp|O94874|UFL1_HUMAN 1 1175.6214 1.04 4584 16531 2 1175.621331 588.818 E3 UFM1-protein ligase 1 OS=Homo sapiens OX=9606 GN=UFL1 PE=1 SV=2 5.88 3332 - 996509 - - - -0.0834 - 1.806 0.284 - 245.3 1 2 0 -0.0001 10 0 0 0 1.63E+07 1.56E+07 - - - 2.7886 0.9995 221125_WJC_METTL3_EV_vs_WT_F01.16532.16532.2 0.0725 22-Nov K.ALLTPVAIAAGR.K sp|P00390|GSHR_HUMAN 1 1151.7026 0.44 4585 16532 2 1151.70473 576.8586 "Glutathione reductase, mitochondrial OS=Homo sapiens OX=9606 GN=GSR PE=1 SV=2" 9.79 3332.1 - 709081 - - - 1.8121 - 2.46 0.325 - 419.2 1 2 0 0.0021 12 0 0 0 1.06E+07 2.40E+07 - - - 3.8093 0.9994 221125_WJC_METTL3_EV_vs_WT_F01.16534.16534.2 0.00112 16-Aug R.ELLTEFGYK.G sp|P49411|EFTU_HUMAN 1 1098.5597 1.08 4587 16534 2 1098.560844 550.2871 "Elongation factor Tu, mitochondrial OS=Homo sapiens OX=9606 GN=TUFM PE=1 SV=2" 4.53 3332.3 - 449125 - - - 1.0168 - 1.508 0.382 - 196.3 1 2 0 0.0011 9 0 0 0 3.31E+07 3.06E+07 - - - 3.0505 0.9995 221125_WJC_METTL3_EV_vs_WT_F01.16537.16537.2 0.00256 22-Sep -.MVPPVQVSPLIK[136.11].L sp|P56385|ATP5I_HUMAN 1 1314.7825 1.94 4590 16537 2 1314.784139 658.3985 "ATP synthase subunit e, mitochondrial OS=Homo sapiens OX=9606 GN=ATP5ME PE=1 SV=2" 8.5 3332.7 - 243247 - - - 1.2618 - 1.836 0.38 - 169.2 1 2 0 0.0017 12 0 0 0 1.23E+07 6.34E+06 - - - 3.4458 0.9989 221125_WJC_METTL3_EV_vs_WT_F01.16543.16543.2 0.381 18-Aug R.ALEAELAALR.Q sp|Q16352|AINX_HUMAN 1 1055.5975 1.57 4594 16543 2 1055.598267 528.806 Alpha-internexin OS=Homo sapiens OX=9606 GN=INA PE=1 SV=2 4.53 3333.5 - 3.64E+06 - - - 0.7181 - 1.869 0.223 - 210.3 1 2 0 0.0008 10 0 0 0 5.40E+07 3.44E+07 - - - 2.4335 0.9994 221125_WJC_METTL3_EV_vs_WT_F01.16544.16544.2 0.00723 18-Oct R.LGLSTLGELK.Q "sp|O43399|TPD54_HUMAN,tr|A0A087WZ51|A0A087WZ51_HUMAN,tr|A0A087WYR3|A0A087WYR3_HUMAN" 3 1029.607 1.58 4595 16544 2 1029.608495 515.8108 Tumor protein D54 OS=Homo sapiens OX=9606 GN=TPD52L2 PE=1 SV=2 6 3333.6 - 3.70E+06 - - - 1.4413 - 1.886 0.353 - 213.7 1 2 0 0.0015 10 0 0 0 1.07E+08 6.80E+07 - - - 3.4188 0.9995 221125_WJC_METTL3_EV_vs_WT_F01.16545.16545.2 0.00237 18-Sep K.VVPEMTEILK.K "sp|P13804|ETFA_HUMAN,tr|H0YK49|H0YK49_HUMAN,tr|H0YL83|H0YL83_HUMAN" 3 1157.6366 1.7 4596 16545 2 1157.637029 579.8256 "Electron transfer flavoprotein subunit alpha, mitochondrial OS=Homo sapiens OX=9606 GN=ETFA PE=1 SV=1" 4.53 3333.6 - 2.89E+06 - - - 0.3732 - 1.659 0.357 - 328.5 1 2 0 0.0004 10 0 0 0 1.02E+08 6.02E+07 - - - 3.0907 0.9998 221125_WJC_METTL3_EV_vs_WT_F01.16546.16546.2 0.000596 18-Oct R.LGLSTLGELK[136.11].Q "sp|O43399|TPD54_HUMAN,tr|A0A087WZ51|A0A087WZ51_HUMAN,tr|A0A087WYR3|A0A087WYR3_HUMAN" 3 1037.6212 1.63 4597 16546 2 1037.621919 519.8179 Tumor protein D54 OS=Homo sapiens OX=9606 GN=TPD52L2 PE=1 SV=2 6 3333.7 - 2.58E+06 - - - 0.6823 - 2.16 0.396 - 212.6 1 2 0 0.0007 10 0 0 0 1.07E+08 6.53E+07 - - - 4.1152 0.9997 221125_WJC_METTL3_EV_vs_WT_F01.16547.16547.2 0.00183 18-Sep K.AVFVPDIYSR.T sp|O94874|UFL1_HUMAN 1 1165.6132 1.09 4598 16547 2 1165.613656 583.8139 E3 UFM1-protein ligase 1 OS=Homo sapiens OX=9606 GN=UFL1 PE=1 SV=2 5.88 3333.7 - 1.89E+06 - - - 0.4264 - 1.827 0.398 - 329 1 2 0 0.0005 10 0 0 0 1.63E+07 1.49E+07 - - - 3.6627 0.9994 221125_WJC_METTL3_EV_vs_WT_F01.16551.16551.2 0.00496 22-Oct -.MVPPVQVSPLIK.L sp|P56385|ATP5I_HUMAN 1 1306.7683 2.07 4602 16551 2 1306.769089 654.3914 "ATP synthase subunit e, mitochondrial OS=Homo sapiens OX=9606 GN=ATP5ME PE=1 SV=2" 8.5 3334.2 - 603336 - - - 0.6191 - 1.762 0.32 - 203.4 1 2 0 0.0008 12 0 0 0 1.56E+07 7.51E+06 - - - 2.8947 0.9596 221125_WJC_METTL3_EV_vs_WT_F01.16554.16554.2 0.255 16-Sep R.WGEPEPFLR[166.11].L "sp|P28340|DPOD1_HUMAN,tr|M0QZR8|M0QZR8_HUMAN,tr|A0A2R8Y7K6|A0A2R8Y7K6_HUMAN,tr|M0R2B7|M0R2B7_HUMAN,tr|A0A087WYJ2|A0A087WYJ2_HUMAN" 5 1139.5639 0.47 4605 16554 2 1139.569534 570.7892 DNA polymerase delta catalytic subunit OS=Homo sapiens OX=9606 GN=POLD1 PE=1 SV=2 4.53 3334.6 - 280414 - - - 4.9317 - 1.409 0.227 - 242.6 1 2 0 0.0056 9 0 0 0 1.55E+06 3.29E+06 - - - 1.7078 0.9888 221125_WJC_METTL3_EV_vs_WT_F01.16556.16556.2 0.403 14-Jul R.LLLAALGR[166.11].R "sp|P30876|RPB2_HUMAN,tr|C9J4M6|C9J4M6_HUMAN,tr|C9J2Y9|C9J2Y9_HUMAN" 3 835.5519 1.04 4607 16556 2 835.552169 418.7832 DNA-directed RNA polymerase II subunit RPB2 OS=Homo sapiens OX=9606 GN=POLR2B PE=1 SV=1 9.75 3334.8 - 227120 - - - 0.3303 - 1.316 0.095 - 134.5 1 2 0 0.0003 8 0 0 0 6.15E+06 5.92E+06 - - - 0.5708 0.9466 221125_WJC_METTL3_EV_vs_WT_F01.16558.16558.2 0.0054 22-Jun H.LVPVYDVEPLEK[136.11].L "sp|Q6P2Q9|PRP8_HUMAN,tr|I3L0J9|I3L0J9_HUMAN" 2 1407.7741 1.43 4609 16558 2 1407.773341 704.8943 Pre-mRNA-processing-splicing factor 8 OS=Homo sapiens OX=9606 GN=PRPF8 PE=1 SV=2 4.14 3335.1 - 189695 - - - -0.5271 - 1.242 0.385 - 80.2 1 1 0 -0.0007 12 0 0 0 1.86E+06 1.30E+06 - - - 2.4546 0.9154 221125_WJC_METTL3_EV_vs_WT_F01.16562.16562.2 2.34 16-May K.C[160.03]SLPATLSR[166.11].S "sp|Q9NQ88|TIGAR_HUMAN,tr|A0A0U1RQD1|A0A0U1RQD1_HUMAN,tr|A0A6Q8PFP0|A0A6Q8PFP0_HUMAN" 3 1013.5203 0.01 4611 16562 2 1013.520126 507.7674 "Fructose-2,6-bisphosphatase TIGAR OS=Homo sapiens OX=9606 GN=TIGAR PE=1 SV=1" 8.25 3335.7 - 2.85E+06 - - - -0.2062 - 0.92 0.056 - 47.5 1 2 0 -0.0002 9 0 0 0 8.28E+05 1.42E+08 - - - -0.7867 0.9948 221125_WJC_METTL3_EV_vs_WT_F01.16564.16564.2 1.29 12-Jun R.EIVWLER[166.11].E "sp|Q14244|MAP7_HUMAN,tr|A0A087WZ40|A0A087WZ40_HUMAN" 2 953.521 1.17 4613 16564 2 953.523038 477.7678 Ensconsin OS=Homo sapiens OX=9606 GN=MAP7 PE=1 SV=1 4.53 3335.8 - 1.54E+06 - - - 2.151 - 1.327 0.25 - 179.1 1 2 0 0.0021 7 0 0 0 3.80E+07 3.24E+07 - - - 1.7833 0.999 221125_WJC_METTL3_EV_vs_WT_F01.16565.16565.2 0.232 14-Jun R.ITVLEALR.H "sp|Q5T2N8|ATD3C_HUMAN,sp|Q5T9A4|ATD3B_HUMAN,sp|Q9NVI7|ATD3A_HUMAN,tr|A0A5K1VW56|A0A5K1VW56_HUMAN" 4 913.5597 1.11 4614 16565 2 913.560807 457.7871 ATPase family AAA domain-containing protein 3C OS=Homo sapiens OX=9606 GN=ATAD3C PE=2 SV=2 6 3335.9 - 1.44E+06 - - - 1.2479 - 1.634 0.303 - 112.3 1 2 0 0.0011 8 0 0 0 6.50E+07 5.84E+07 - - - 2.7595 0.9988 221125_WJC_METTL3_EV_vs_WT_F01.16566.16566.2 0.0199 14-Sep K.TLVLLMGK.E "sp|P07737|PROF1_HUMAN,tr|K7EJ44|K7EJ44_HUMAN" 2 873.5358 1.04 4615 16566 2 873.536767 437.7752 Profilin-1 OS=Homo sapiens OX=9606 GN=PFN1 PE=1 SV=2 8.41 3336 - 723570 - - - 1.1516 - 1.466 0.318 - 311.1 1 2 0 0.001 8 0 0 0 4.59E+07 4.44E+07 - - - 2.5431 0.9938 221125_WJC_METTL3_EV_vs_WT_F01.16571.16571.2 0.282 12-Jun R.DGFGFIK.C "sp|O75534|CSDE1_HUMAN,tr|E9PLT0|E9PLT0_HUMAN" 2 782.3963 0.48 4620 16571 2 782.396997 392.2054 Cold shock domain-containing protein E1 OS=Homo sapiens OX=9606 GN=CSDE1 PE=1 SV=2 5.84 3336.5 - 304093 - - - 0.9036 - 1.179 0.21 - 130.4 1 2 0 0.0007 7 0 0 0 1.63E+07 3.37E+07 - - - 1.1136 0.9996 221125_WJC_METTL3_EV_vs_WT_F01.16573.16573.2 0.000543 20-Aug R.FEEAPDYMYLR.Q "sp|P48729|KC1A_HUMAN,tr|H0Y9X2|H0Y9X2_HUMAN,tr|A0A590UJ43|A0A590UJ43_HUMAN,tr|D6REM4|D6REM4_HUMAN,tr|E7ETM0|E7ETM0_HUMAN,tr|U3KPX3|U3KPX3_HUMAN,tr|A0A5F9W493|A0A5F9W493_HUMAN,tr|U3KQK7|U3KQK7_HUMAN" 8 1432.6333 2.14 4622 16573 2 1432.635535 717.3239 Casein kinase I isoform alpha OS=Homo sapiens OX=9606 GN=CSNK1A1 PE=1 SV=2 4.14 3336.7 - 116519 - - - 1.558 - 1.757 0.465 - 162.1 1 2 0 0.0022 11 0 0 0 7.76E+05 3.62E+05 - - - 3.9995 0.989 221125_WJC_METTL3_EV_vs_WT_F01.16576.16576.2 0.177 22-Jun R.MPGSVIPPPLVR.G sp|Q86YP4|P66A_HUMAN 1 1261.7217 1.54 4624 16576 2 1261.723593 631.8681 Transcriptional repressor p66-alpha OS=Homo sapiens OX=9606 GN=GATAD2A PE=1 SV=1 9.5 3337.1 - 81182.5 - - - 1.5289 - 1.372 0.144 - 94.7 1 2 0 0.0019 12 0 0 0 1.14E+07 7.41E+06 - - - 0.9361 0.9962 221125_WJC_METTL3_EV_vs_WT_F01.16579.16579.2 0.0476 14-Jul K.TLVLLMGK[136.11].E "sp|P07737|PROF1_HUMAN,tr|K7EJ44|K7EJ44_HUMAN" 2 881.55 1.04 4626 16579 2 881.550937 441.7823 Profilin-1 OS=Homo sapiens OX=9606 GN=PFN1 PE=1 SV=2 8.41 3337.4 - 2.11E+06 - - - 1.1071 - 1.484 0.179 - 169.3 1 2 0 0.001 8 0 0 0 4.69E+07 4.49E+07 - - - 1.5533 0.9999 221125_WJC_METTL3_EV_vs_WT_F01.16580.16580.2 1.92E-05 13/18 K.VTDAIVLLDR.E "sp|P11172|UMPS_HUMAN,tr|E9PFD2|E9PFD2_HUMAN" 2 1113.6394 0.85 4627 16580 2 1113.640494 557.827 Uridine 5'-monophosphate synthase OS=Homo sapiens OX=9606 GN=UMPS PE=1 SV=1 4.21 3337.4 - 1.35E+06 - - - 1.0057 - 2.831 0.5 - 881.2 1 2 0 0.0011 10 0 0 0 2.91E+07 3.43E+07 - - - 5.6384 0.9996 221125_WJC_METTL3_EV_vs_WT_F01.16585.16585.2 0.0167 18-Nov R.LVLSTFSNIR.E sp|Q8WVV4|POF1B_HUMAN 1 1148.6554 999 4632 16585 2 1148.657431 575.335 Protein POF1B OS=Homo sapiens OX=9606 GN=POF1B PE=1 SV=3 9.75 3338.1 - 653718 - - - 1.8038 - 2.01 0.418 - 436.6 1 2 0 0.0021 10 0 0 0 8.17E+06 0.00E+00 - - - 4.0764 0.9302 221125_WJC_METTL3_EV_vs_WT_F01.16587.16587.2 0.998 22-Apr R.TEADVEEEALR[166.11]R[166.11].K "sp|Q9BV36|MELPH_HUMAN,tr|H7C3K9|H7C3K9_HUMAN,tr|H7C2D8|H7C2D8_HUMAN,tr|H7C371|H7C371_HUMAN" 4 1436.701 0.21 4634 16587 2 1436.695315 719.3578 Melanophilin OS=Homo sapiens OX=9606 GN=MLPH PE=1 SV=1 4.25 3338.3 - 283017 - - - -3.9751 - 0.938 0.256 - 40.6 1 2 0 -0.0057 12 0 0 0 5.01E+05 2.40E+06 - - - 0.7616 0.9986 221125_WJC_METTL3_EV_vs_WT_F01.16589.16589.2 8.45E-06 24-Oct R.ILGVGPDDPDLVR[166.11].A "sp|P48449|LSS_HUMAN,tr|C9J315|C9J315_HUMAN" 2 1374.7383 2.08 4636 16589 2 1374.74423 688.3764 Lanosterol synthase OS=Homo sapiens OX=9606 GN=LSS PE=1 SV=1 3.93 3338.6 - 203698 - - - 4.3499 - 2.11 0.551 - 358 1 2 0 0.006 13 0 0 0 5.70E+06 2.74E+06 - - - 5.0252 0.9992 221125_WJC_METTL3_EV_vs_WT_F01.16590.16590.2 5.96E-05 24-Oct R.ILGVGPDDPDLVR.A "sp|P48449|LSS_HUMAN,tr|C9J315|C9J315_HUMAN" 2 1364.73 2.08 4637 16590 2 1364.734734 683.3723 Lanosterol synthase OS=Homo sapiens OX=9606 GN=LSS PE=1 SV=1 3.93 3338.7 - 167323 - - - 3.4835 - 1.989 0.532 - 339.6 1 2 0 0.0048 13 0 0 0 5.70E+06 2.74E+06 - - - 4.7337 0.9983 221125_WJC_METTL3_EV_vs_WT_F01.16593.16593.2 0.0415 14-Aug K.AGPIWDLR.L "sp|O60506|HNRPQ_HUMAN,sp|O43390|HNRPR_HUMAN,tr|B4DT28|B4DT28_HUMAN,tr|A0A7I2YQN2|A0A7I2YQN2_HUMAN,tr|A0A7I2V5Q6|A0A7I2V5Q6_HUMAN,tr|A0A7I2V4Z0|A0A7I2V4Z0_HUMAN,tr|B7Z645|B7Z645_HUMAN,tr|A0A6Q8PH31|A0A6Q8PH31_HUMAN,tr|A0A6Q8PEX7|A0A6Q8PEX7_HUMAN,tr|A0A7I2V2F2|A0A7I2V2F2_HUMAN,tr|A0A7I2V346|A0A7I2V346_HUMAN,tr|A0A7I2V309|A0A7I2V309_HUMAN,tr|A0A6Q8PH35|A0A6Q8PH35_HUMAN" 13 926.4974 1.28 4639 16593 2 926.498673 464.256 Heterogeneous nuclear ribonucleoprotein Q OS=Homo sapiens OX=9606 GN=SYNCRIP PE=1 SV=2 5.88 3339.1 - 3.96E+06 - - - 1.3729 - 1.367 0.317 - 238.9 1 2 0 0.0013 8 0 0 0 3.25E+08 2.55E+08 - - - 2.3248 0.9961 221125_WJC_METTL3_EV_vs_WT_F01.16594.16594.2 0.0229 14-Jul K.VFLENVIR.D sp|P62805|H4_HUMAN 1 988.5706 1.12 4640 16594 2 988.57275 495.2926 Histone H4 OS=Homo sapiens OX=9606 GN=H4C1 PE=1 SV=2 5.97 3339.1 - 1.17E+06 - - - 2.2093 - 1.47 0.248 - 195.6 1 2 0 0.0022 8 0 0 0 5.27E+09 4.71E+09 - - - 2.034 0.9996 221125_WJC_METTL3_EV_vs_WT_F01.16595.16595.2 0.00491 14-Sep R.ITVLEALR[166.11].H "sp|Q5T2N8|ATD3C_HUMAN,sp|Q5T9A4|ATD3B_HUMAN,sp|Q9NVI7|ATD3A_HUMAN,tr|A0A5K1VW56|A0A5K1VW56_HUMAN" 4 923.5679 1.11 4641 16595 2 923.568785 462.7912 ATPase family AAA domain-containing protein 3C OS=Homo sapiens OX=9606 GN=ATAD3C PE=2 SV=2 6 3339.2 - 6.71E+06 - - - 0.9182 - 1.884 0.367 - 310.1 1 2 0 0.0008 8 0 0 0 6.50E+07 5.84E+07 - - - 3.6617 0.9999 221125_WJC_METTL3_EV_vs_WT_F01.16598.16598.2 0.000782 14-Sep K.VDLVLLGK[136.11].Q sp|P38117|ETFB_HUMAN 1 863.5572 0.93 4644 16598 2 863.557532 432.7859 Electron transfer flavoprotein subunit beta OS=Homo sapiens OX=9606 GN=ETFB PE=1 SV=3 5.81 3339.4 - 1.45E+06 - - - 0.4377 - 1.982 0.477 - 316 1 2 0 0.0004 8 0 0 0 9.75E+07 1.05E+08 - - - 4.6272 0.9593 221125_WJC_METTL3_EV_vs_WT_F01.16600.16600.2 1.92 12-Jun K.EGIILFK.E sp|P05455|LA_HUMAN 1 818.4902 0.93 4646 16600 2 818.491336 410.2524 Lupus La protein OS=Homo sapiens OX=9606 GN=SSB PE=1 SV=2 6.1 3339.6 - 453456 - - - 1.3989 - 1.139 0.074 - 123.3 1 2 0 0.0011 7 0 0 0 1.08E+08 1.16E+08 - - - -0.0004 0.9998 221125_WJC_METTL3_EV_vs_WT_F01.16603.16603.2 0.000105 22-Nov K.VLQGDLVMNVYR[166.11].D "sp|P49327|FAS_HUMAN,tr|A0A0U1RQF0|A0A0U1RQF0_HUMAN" 2 1415.747 0.4 4649 16603 2 1415.747166 708.8808 Fatty acid synthase OS=Homo sapiens OX=9606 GN=FASN PE=1 SV=3 5.81 3340 - 331060 - - - 0.0883 - 2.146 0.438 - 493.8 1 2 0 0.0001 12 0 0 0 1.65E+06 4.14E+06 - - - 4.2852 0.9997 221125_WJC_METTL3_EV_vs_WT_F01.16604.16604.2 5.09E-05 22-Oct K.VLQGDLVMNVYR.D "sp|P49327|FAS_HUMAN,tr|A0A0U1RQF0|A0A0U1RQF0_HUMAN" 2 1405.7388 0.4 4650 16604 2 1405.739349 703.8767 Fatty acid synthase OS=Homo sapiens OX=9606 GN=FASN PE=1 SV=3 5.81 3340.2 - 184883 - - - 0.4112 - 1.877 0.419 - 248.1 1 2 0 0.0006 12 0 0 0 1.65E+06 4.14E+06 - - - 3.7923 0.9925 221125_WJC_METTL3_EV_vs_WT_F01.16605.16605.2 0.0562 22-Apr K.ILLNAC[160.03]C[160.03]PGWVR.T sp|P16152|CBR1_HUMAN 1 1457.7272 1.41 4651 16605 2 1457.733141 729.8709 Carbonyl reductase [NADPH] 1 OS=Homo sapiens OX=9606 GN=CBR1 PE=1 SV=3 8.07 3340.3 - 141053 - - - 4.1023 - 1.297 0.397 - 48.1 1 2 0 0.006 12 0 0 0 3.69E+06 2.62E+06 - - - 2.6556 0.9996 221125_WJC_METTL3_EV_vs_WT_F01.16609.16609.2 0.00139 14-Aug K.VDLVLLGK.Q sp|P38117|ETFB_HUMAN 1 855.543 1.03 4654 16609 2 855.544267 428.7788 Electron transfer flavoprotein subunit beta OS=Homo sapiens OX=9606 GN=ETFB PE=1 SV=3 5.81 3340.8 - 5.41E+06 - - - 1.5347 - 1.772 0.429 - 245.4 1 2 0 0.0013 8 0 0 0 9.75E+07 9.48E+07 - - - 3.9346 0.9997 221125_WJC_METTL3_EV_vs_WT_F01.16612.16612.2 0.0171 16-Oct R.FAVGIVIGR.N "sp|Q96I24|FUBP3_HUMAN,sp|Q96AE4|FUBP1_HUMAN,tr|E9PEB5|E9PEB5_HUMAN" 3 930.5651 1.76 4657 16612 2 930.565868 466.2898 Far upstream element-binding protein 3 OS=Homo sapiens OX=9606 GN=FUBP3 PE=1 SV=2 9.75 3341.1 - 1.34E+06 - - - 0.8393 - 2.064 0.392 - 359.2 1 2 0 0.0008 9 0 0 0 3.22E+08 1.83E+08 - - - 4.0325 0.9825 221125_WJC_METTL3_EV_vs_WT_F01.16613.16613.2 0.00116 16-Nov F.ADALLIIPK[136.11].V "sp|Q92526|TCPW_HUMAN,sp|P40227|TCPZ_HUMAN" 2 960.6099 0.53 4658 16613 2 960.610768 481.3122 T-complex protein 1 subunit zeta-2 OS=Homo sapiens OX=9606 GN=CCT6B PE=1 SV=5 5.88 3341.2 - 1.18E+06 - - - 0.8849 - 1.917 0.398 - 366.1 1 1 0 0.0008 9 0 0 0 1.08E+08 2.04E+08 - - - 3.863 0.9969 221125_WJC_METTL3_EV_vs_WT_F01.16614.16614.2 1.09E-05 18-Aug R.FFNYVPSGIR[166.11].C "sp|Q969X6|UTP4_HUMAN,tr|H3BPD7|H3BPD7_HUMAN" 2 1208.6218 2.09 4659 16614 2 1208.626405 605.3182 U3 small nucleolar RNA-associated protein 4 homolog OS=Homo sapiens OX=9606 GN=UTP4 PE=1 SV=1 8.75 3341.2 - 1.03E+06 - - - 3.8399 - 1.571 0.411 - 210.4 1 2 0 0.0046 10 0 0 0 2.70E+07 1.29E+07 - - - 3.3361 0.9597 221125_WJC_METTL3_EV_vs_WT_F01.16615.16615.2 0.0723 12-Jun K.LYLVFSK.E sp|P57740|NU107_HUMAN 1 868.5058 0.63 4660 16615 2 868.505841 435.2602 Nuclear pore complex protein Nup107 OS=Homo sapiens OX=9606 GN=NUP107 PE=1 SV=1 8.59 3341.3 - 595723 - - - 0 - 1.229 0.001 - 110.9 1 2 0 0 7 0 0 0 6.65E+06 1.06E+07 - - - -0.2983 0.9901 221125_WJC_METTL3_EV_vs_WT_F01.16616.16616.2 12.5 12-Jul K.ALLLELK[136.11].G sp|P49427|UB2R1_HUMAN 1 806.5357 0.75 4661 16616 2 806.536304 404.2751 Ubiquitin-conjugating enzyme E2 R1 OS=Homo sapiens OX=9606 GN=CDC34 PE=1 SV=2 6.05 3341.4 - 306039 - - - 0.76 - 1.283 0.124 - 146 1 2 0 0.0006 7 0 0 0 2.50E+06 3.33E+06 - - - 0.7463 0.9957 221125_WJC_METTL3_EV_vs_WT_F01.16620.16620.2 0.000247 14-Sep K.LMNLWTER[166.11].F "sp|P52732|KIF11_HUMAN,tr|A0A7I2V3A9|A0A7I2V3A9_HUMAN" 2 1071.5411 4.46 4664 16620 2 1071.535316 536.7778 Kinesin-like protein KIF11 OS=Homo sapiens OX=9606 GN=KIF11 PE=1 SV=2 6 3341.9 - 1.64E+06 - - - -5.3708 - 1.851 0.46 - 396.6 1 2 0 -0.0058 8 0 0 0 8.42E+08 1.89E+08 - - - 4.2938 0.9946 221125_WJC_METTL3_EV_vs_WT_F01.16622.16622.2 0.226 14-Aug K.AGISFIIK.R "sp|P78347|GTF2I_HUMAN,tr|A0A494C1K3|A0A494C1K3_HUMAN" 2 847.5167 1.29 4665 16622 2 847.517594 424.7656 General transcription factor II-I OS=Homo sapiens OX=9606 GN=GTF2I PE=1 SV=2 8.8 3342.1 - 7.94E+06 - - - 1.0076 - 1.458 0.146 - 152.5 1 2 0 0.0009 8 0 0 0 1.88E+09 1.45E+09 - - - 1.2563 0.9989 221125_WJC_METTL3_EV_vs_WT_F01.16624.16624.2 0.000881 18-Dec K.VTDAIVLLDR[166.11].E "sp|P11172|UMPS_HUMAN,tr|E9PFD2|E9PFD2_HUMAN" 2 1123.6476 0.85 4667 16624 2 1123.651509 562.8311 Uridine 5'-monophosphate synthase OS=Homo sapiens OX=9606 GN=UMPS PE=1 SV=1 4.21 3342.2 - 4.71E+06 - - - 3.4397 - 2.143 0.415 - 450.7 1 2 0 0.0039 10 0 0 0 2.91E+07 3.43E+07 - - - 4.2325 0.9033 221125_WJC_METTL3_EV_vs_WT_F01.16625.16625.2 5.34 12-May K.EGIILFK[136.11].E sp|P05455|LA_HUMAN 1 826.5044 0.93 4668 16625 2 826.504801 414.2595 Lupus La protein OS=Homo sapiens OX=9606 GN=SSB PE=1 SV=2 6.1 3342.3 - 4.04E+06 - - - 0.4961 - 1.087 0.001 - 91.8 2 2 0 0.0004 7 0 0 0 1.08E+08 1.16E+08 - - - -0.8219 0.9997 221125_WJC_METTL3_EV_vs_WT_F01.16628.16628.2 0.000653 16-Oct R.FAVGIVIGR[166.11].N "sp|Q96I24|FUBP3_HUMAN,sp|Q96AE4|FUBP1_HUMAN,tr|E9PEB5|E9PEB5_HUMAN" 3 940.5734 1.75 4671 16628 2 940.574272 471.294 Far upstream element-binding protein 3 OS=Homo sapiens OX=9606 GN=FUBP3 PE=1 SV=2 9.75 3342.4 - 2.59E+06 - - - 0.9728 - 2.093 0.388 - 334 1 2 0 0.0009 9 0 0 0 3.13E+08 1.78E+08 - - - 4.0433 0.9496 221125_WJC_METTL3_EV_vs_WT_F01.16632.16632.2 2.53 12-May K.EFSMMFK.H "sp|Q13813|SPTN1_HUMAN,tr|A0A0D9SF54|A0A0D9SF54_HUMAN,tr|A0A0D9SGF6|A0A0D9SGF6_HUMAN" 3 918.3979 2.38 4675 16632 2 918.398301 460.2062 "Spectrin alpha chain, non-erythrocytic 1 OS=Homo sapiens OX=9606 GN=SPTAN1 PE=1 SV=3" 6.1 3342.9 - 535215 - - - 0.3855 - 0.871 0.134 - 62.3 1 2 0 0.0004 7 0 0 0 9.07E+06 3.80E+06 - - - -0.407 0.8591 221125_WJC_METTL3_EV_vs_WT_F01.16635.16635.2 6.72 18-Jun R.LLYEALVDC[160.03]K[136.11].K "sp|Q7L2H7|EIF3M_HUMAN,tr|J3KNJ2|J3KNJ2_HUMAN,tr|E9PRY0|E9PRY0_HUMAN,tr|H0YCQ8|H0YCQ8_HUMAN" 4 1230.641 0.83 4678 16635 2 1230.637379 616.3278 Eukaryotic translation initiation factor 3 subunit M OS=Homo sapiens OX=9606 GN=EIF3M PE=1 SV=1 4.37 3343.2 - 268843 - - - -2.9107 - 1.077 0.11 - 55.9 5 2 0 -0.0036 10 0 0 0 1.95E+06 2.34E+06 - - - -0.2528 0.9996 221125_WJC_METTL3_EV_vs_WT_F01.16636.16636.2 0.000346 22-Aug K.ILLNAC[160.03]C[160.03]PGWVR[166.11].T sp|P16152|CBR1_HUMAN 1 1467.7354 1.41 4679 16636 2 1467.737222 734.875 Carbonyl reductase [NADPH] 1 OS=Homo sapiens OX=9606 GN=CBR1 PE=1 SV=3 8.07 3343.3 - 227417 - - - 1.2202 - 1.644 0.453 - 190.8 1 2 0 0.0018 12 0 0 0 3.69E+06 2.62E+06 - - - 3.6943 0.9735 221125_WJC_METTL3_EV_vs_WT_F01.16639.16639.2 0.00328 18-Jul R.FFNYVPSGIR.C "sp|Q969X6|UTP4_HUMAN,tr|H3BPD7|H3BPD7_HUMAN" 2 1198.6135 1.37 4681 16639 2 1198.621203 600.314 U3 small nucleolar RNA-associated protein 4 homolog OS=Homo sapiens OX=9606 GN=UTP4 PE=1 SV=1 8.75 3343.7 - 1.02E+06 - - - 6.4316 - 1.325 0.424 - 98.6 1 2 0 0.0077 10 0 0 0 1.55E+07 1.13E+07 - - - 2.9558 0.9843 221125_WJC_METTL3_EV_vs_WT_F01.16641.16641.2 0.00317 16-Oct F.ADALLIIPK.V "sp|Q92526|TCPW_HUMAN,sp|P40227|TCPZ_HUMAN" 2 952.5957 0.5 4682 16641 2 952.595991 477.3051 T-complex protein 1 subunit zeta-2 OS=Homo sapiens OX=9606 GN=CCT6B PE=1 SV=5 5.88 3343.9 - 2.83E+06 - - - 0.2866 - 1.798 0.409 - 328.9 1 1 0 0.0003 9 0 0 0 1.01E+08 2.02E+08 - - - 3.7591 0.9976 221125_WJC_METTL3_EV_vs_WT_F01.16643.16643.2 0.262 16-Aug R.GLVGEIIKR.F "sp|P15531|NDKA_HUMAN,sp|P22392|NDKB_HUMAN,tr|Q32Q12|Q32Q12_HUMAN,tr|Q32Q12|Q32Q12_HUMAN,tr|J3KPD9|J3KPD9_HUMAN,tr|F6XY72|F6XY72_HUMAN,tr|E5RHP0|E5RHP0_HUMAN,tr|E7ERL0|E7ERL0_HUMAN,tr|C9K028|C9K028_HUMAN" 9 983.6128 1.21 4684 16643 2 983.613952 492.8137 Nucleoside diphosphate kinase A OS=Homo sapiens OX=9606 GN=NME1 PE=1 SV=1 8.75 3344.1 - 1.23E+06 - - - 1.2068 - 1.556 0.222 - 165.5 1 2 0 0.0012 9 0 0 0 4.42E+08 3.66E+08 - - - 1.9594 0.9765 221125_WJC_METTL3_EV_vs_WT_F01.16644.16644.2 0.0542 14-Aug R.IASFLQLK.N "sp|P42694|HELZ_HUMAN,tr|J3KT20|J3KT20_HUMAN,tr|J3QS41|J3QS41_HUMAN,tr|A0A075B6R3|A0A075B6R3_HUMAN" 4 918.5539 0.85 4685 16644 2 918.557003 460.2842 Probable helicase with zinc finger domain OS=Homo sapiens OX=9606 GN=HELZ PE=1 SV=2 8.75 3344.2 - 1.06E+06 - - - 3.4282 - 1.717 0.085 - 125.9 1 2 0 0.0032 8 0 0 0 6.94E+07 8.17E+07 - - - 1.2982 0.9952 221125_WJC_METTL3_EV_vs_WT_F01.16646.16646.2 0.0474 14-Jul K.AVPSWFVR[166.11].V "sp|P41252|SYIC_HUMAN,tr|A0A804HL54|A0A804HL54_HUMAN,tr|A0A804HKU1|A0A804HKU1_HUMAN,tr|A0A804HK69|A0A804HK69_HUMAN,tr|A0A804HIV9|A0A804HIV9_HUMAN,tr|A0A804HJN6|A0A804HJN6_HUMAN,tr|A0A804HHW9|A0A804HHW9_HUMAN,tr|A0A0A0MSX9|A0A0A0MSX9_HUMAN,tr|J3KR24|J3KR24_HUMAN,tr|A0A804HIG2|A0A804HIG2_HUMAN,tr|A0A804HJ36|A0A804HJ36_HUMAN" 11 970.5264 2.54 4687 16646 2 970.527352 486.2705 "Isoleucine--tRNA ligase, cytoplasmic OS=Homo sapiens OX=9606 GN=IARS1 PE=1 SV=2" 9.79 3344.3 - 535840 - - - 0.9737 - 1.481 0.148 - 173.9 1 2 0 0.0009 8 0 0 0 1.94E+08 7.65E+07 - - - 1.3182 0.9997 221125_WJC_METTL3_EV_vs_WT_F01.16656.16656.2 0.0212 14-Sep R.VDEIIWVK[136.11].T sp|Q86U44|MTA70_HUMAN 1 1008.5735 0.01 4695 16656 2 1008.572542 505.294 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 4.37 3345.7 - 8.26E+06 - - - -0.9826 - 2.17 0.321 - 300.4 1 2 0 -0.001 8 0 0 0 1.25E+06 2.23E+08 - - - 3.7481 0.9973 221125_WJC_METTL3_EV_vs_WT_F01.16657.16657.2 1.38 16-Jun R.GLVGEIIK[136.11]R[166.11].F "sp|P15531|NDKA_HUMAN,sp|P22392|NDKB_HUMAN,tr|Q32Q12|Q32Q12_HUMAN,tr|Q32Q12|Q32Q12_HUMAN,tr|J3KPD9|J3KPD9_HUMAN,tr|F6XY72|F6XY72_HUMAN,tr|E5RHP0|E5RHP0_HUMAN,tr|E7ERL0|E7ERL0_HUMAN,tr|C9K028|C9K028_HUMAN" 9 1001.6352 1.19 4696 16657 2 1001.634105 501.8249 Nucleoside diphosphate kinase A OS=Homo sapiens OX=9606 GN=NME1 PE=1 SV=1 8.75 3345.7 - 5.82E+06 - - - -1.1282 - 1.459 0.217 - 118.1 1 2 0 -0.0011 9 0 0 0 4.22E+08 3.54E+08 - - - 1.7363 0.9997 221125_WJC_METTL3_EV_vs_WT_F01.16658.16658.2 0.246 16-Oct R.VLIFSQMTR.V "sp|O60264|SMCA5_HUMAN,sp|P28370|SMCA1_HUMAN,tr|A0A0A0MRP6|A0A0A0MRP6_HUMAN,tr|B7ZLQ5|B7ZLQ5_HUMAN" 4 1093.5954 0.61 4697 16658 2 1093.594437 547.805 SWI\SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A member 5 OS=Homo sapiens OX=9606 GN=SMARCA5 PE=1 SV=1 9.72 3345.8 - 787419 - - - -0.8815 - 2.078 0.377 - 356.9 1 2 0 -0.001 9 0 0 0 1.51E+07 2.48E+07 - - - 3.9412 0.9996 221125_WJC_METTL3_EV_vs_WT_F01.16661.16661.2 0.0318 16-Sep K.ILAPYLEMK.D "sp|Q96FV9|THOC1_HUMAN,tr|A0A087WWS1|A0A087WWS1_HUMAN" 2 1076.594 1.48 4700 16661 2 1076.594417 539.3043 THO complex subunit 1 OS=Homo sapiens OX=9606 GN=THOC1 PE=1 SV=1 6 3346.2 - 321471 - - - 0.3836 - 1.668 0.377 - 213.5 1 2 0 0.0004 9 0 0 0 1.83E+07 1.24E+07 - - - 3.3056 0.9999 221125_WJC_METTL3_EV_vs_WT_F01.16665.16665.2 1.54E-06 20-Oct R.IDGLAALSMDR.T "sp|Q6W2J9|BCOR_HUMAN,tr|H7BZ37|H7BZ37_HUMAN,tr|H7C2V9|H7C2V9_HUMAN,tr|A0A5F9ZGX7|A0A5F9ZGX7_HUMAN,tr|H7BYY2|H7BYY2_HUMAN,tr|H7C231|H7C231_HUMAN" 6 1160.586 1.05 4702 16665 2 1160.58584 581.3003 BCL-6 corepressor OS=Homo sapiens OX=9606 GN=BCOR PE=1 SV=1 4.21 3346.7 - 1.52E+06 - - - -0.1017 - 2.391 0.503 - 328.6 1 2 0 -0.0001 11 0 0 0 6.02E+07 5.74E+07 - - - 5.1143 0.9457 221125_WJC_METTL3_EV_vs_WT_F01.16668.16668.2 0.00323 20-Sep R.QLYHLGVVEAY.S sp|Q08211|DHX9_HUMAN 1 1290.6608 - 4705 16668 2 1290.664539 646.3377 ATP-dependent RNA helicase A OS=Homo sapiens OX=9606 GN=DHX9 PE=1 SV=4 5.24 3347.1 - 322171 - - - 2.8675 - 1.703 0.464 - 227.4 1 1 0 0.0037 11 0 0 0 - - - - - 3.9072 0.9998 221125_WJC_METTL3_EV_vs_WT_F01.16673.16673.2 0.00103 20-Oct R.IDGLAALSMDR[166.11].T "sp|Q6W2J9|BCOR_HUMAN,tr|H7BZ37|H7BZ37_HUMAN,tr|H7C2V9|H7C2V9_HUMAN,tr|A0A5F9ZGX7|A0A5F9ZGX7_HUMAN,tr|H7BYY2|H7BYY2_HUMAN,tr|H7C231|H7C231_HUMAN" 6 1170.5942 1.08 4708 16673 2 1170.593832 586.3044 BCL-6 corepressor OS=Homo sapiens OX=9606 GN=BCOR PE=1 SV=1 4.21 3347.6 - 1.46E+06 - - - -0.3383 - 2.252 0.417 - 339.8 1 2 0 -0.0004 11 0 0 0 6.02E+07 5.55E+07 - - - 4.317 0.9897 221125_WJC_METTL3_EV_vs_WT_F01.16674.16674.2 2.13 14-Jul R.EILETLIK[136.11].G "sp|Q06210|GFPT1_HUMAN,tr|A0A6I8PTT9|A0A6I8PTT9_HUMAN,tr|A0A6I8PRT6|A0A6I8PRT6_HUMAN" 3 965.5888 1 4709 16674 2 965.589487 483.8017 Glutamine--fructose-6-phosphate aminotransferase [isomerizing] 1 OS=Homo sapiens OX=9606 GN=GFPT1 PE=1 SV=3 4.53 3347.7 - 615714 - - - 0.6607 - 1.351 0.101 - 142.4 1 2 0 0.0006 8 0 0 0 1.47E+08 1.47E+08 - - - 0.6941 0.9996 221125_WJC_METTL3_EV_vs_WT_F01.16684.16684.2 0.0369 16-Sep K.ILAPYLEMK[136.11].D "sp|Q96FV9|THOC1_HUMAN,tr|A0A087WWS1|A0A087WWS1_HUMAN" 2 1084.6082 1.53 4715 16684 2 1084.607093 543.3114 THO complex subunit 1 OS=Homo sapiens OX=9606 GN=THOC1 PE=1 SV=1 6 3349.1 - 597107 - - - -1.0243 - 1.78 0.368 - 204.4 1 2 0 -0.0011 9 0 0 0 1.93E+07 1.26E+07 - - - 3.4269 0.9998 221125_WJC_METTL3_EV_vs_WT_F01.16686.16686.2 0.000226 14-Sep K.LMNLWTER.F "sp|P52732|KIF11_HUMAN,tr|A0A7I2V3A9|A0A7I2V3A9_HUMAN" 2 1061.5328 4.45 4716 16686 2 1061.532122 531.7737 Kinesin-like protein KIF11 OS=Homo sapiens OX=9606 GN=KIF11 PE=1 SV=2 6 3349.3 - 4.20E+07 - - - -0.6396 - 1.896 0.432 - 397.7 1 2 0 -0.0007 8 0 0 0 8.44E+08 1.90E+08 - - - 4.161 0.9999 221125_WJC_METTL3_EV_vs_WT_F01.16688.16688.2 2.59E-06 14-Sep K.MVGFIIGR.G "sp|Q96I24|FUBP3_HUMAN,sp|Q96AE4|FUBP1_HUMAN,tr|E9PEB5|E9PEB5_HUMAN,tr|C9JSZ1|C9JSZ1_HUMAN" 4 891.5 1.59 4717 16688 2 891.499513 446.7573 Far upstream element-binding protein 3 OS=Homo sapiens OX=9606 GN=FUBP3 PE=1 SV=2 9.5 3349.5 - 1.06E+08 - - - -0.5956 - 1.843 0.559 - 304.2 1 2 0 -0.0005 8 0 0 0 2.65E+09 1.66E+09 - - - 5.0135 0.9985 221125_WJC_METTL3_EV_vs_WT_F01.16691.16691.2 0.161 20-Sep K.ILITTVPPNLR[166.11].K "sp|Q12905|ILF2_HUMAN,tr|B4DY09|B4DY09_HUMAN" 2 1245.7684 1.32 4720 16691 2 1245.767198 623.8915 Interleukin enhancer-binding factor 2 OS=Homo sapiens OX=9606 GN=ILF2 PE=1 SV=2 9.75 3349.9 - 419218 - - - -0.9873 - 1.63 0.247 - 274.6 1 2 0 -0.0012 11 0 0 0 1.73E+07 1.32E+07 - - - 2.1867 0.9996 221125_WJC_METTL3_EV_vs_WT_F01.16697.16697.2 0.00917 20-Nov K.ILITTVPPNLR.K "sp|Q12905|ILF2_HUMAN,tr|B4DY09|B4DY09_HUMAN" 2 1235.7602 1.34 4724 16697 2 1235.76127 618.8874 Interleukin enhancer-binding factor 2 OS=Homo sapiens OX=9606 GN=ILF2 PE=1 SV=2 9.75 3350.6 - 520126 - - - 0.8999 - 2.171 0.322 - 448.5 1 2 0 0.0011 11 0 0 0 1.68E+07 1.26E+07 - - - 3.516 0.9834 221125_WJC_METTL3_EV_vs_WT_F01.16700.16700.2 1.46 14-Jun R.EILETLIK.G "sp|Q06210|GFPT1_HUMAN,tr|A0A6I8PTT9|A0A6I8PTT9_HUMAN,tr|A0A6I8PRT6|A0A6I8PRT6_HUMAN" 3 957.5746 1 4725 16700 2 957.573665 479.7946 Glutamine--fructose-6-phosphate aminotransferase [isomerizing] 1 OS=Homo sapiens OX=9606 GN=GFPT1 PE=1 SV=3 4.53 3351.1 - 5.77E+06 - - - -1.0276 - 1.385 0.052 - 112.2 1 2 0 -0.001 8 0 0 0 1.47E+08 1.47E+08 - - - 0.4071 0.9996 221125_WJC_METTL3_EV_vs_WT_F01.16701.16701.2 4.47E-05 16-Sep R.AGFVPVYLR.Q "sp|Q9H0A0|NAT10_HUMAN,tr|A0A087WV29|A0A087WV29_HUMAN" 2 1020.5757 0.37 4726 16701 2 1020.573491 511.2951 RNA cytidine acetyltransferase OS=Homo sapiens OX=9606 GN=NAT10 PE=1 SV=2 8.79 3351.1 - 1.98E+06 - - - -2.1174 - 1.643 0.498 - 244.4 1 2 0 -0.0022 9 0 0 0 4.38E+07 1.19E+08 - - - 4.155 0.9856 221125_WJC_METTL3_EV_vs_WT_F01.16702.16702.2 0.000237 16-Aug F.VLVLYDEIK.K "sp|P12235|ADT1_HUMAN,sp|P05141|ADT2_HUMAN,sp|P12236|ADT3_HUMAN" 3 1090.6274 1.07 4727 16702 2 1090.627209 546.321 ADP\ATP translocase 1 OS=Homo sapiens OX=9606 GN=SLC25A4 PE=1 SV=4 4.37 3351.3 - 424391 - - - -0.1861 - 1.737 0.431 - 201.4 1 1 0 -0.0002 9 0 0 0 9.65E+06 9.05E+06 - - - 3.8217 0.9995 221125_WJC_METTL3_EV_vs_WT_F01.16704.16704.2 0.00719 18-Sep R.LLDYVPIGPR.F "sp|P46459|NSF_HUMAN,tr|K7EQD6|K7EQD6_HUMAN,tr|I3L0N3|I3L0N3_HUMAN,tr|I3L2G1|I3L2G1_HUMAN" 4 1141.6495 1.69 4729 16704 2 1141.649779 571.832 Vesicle-fusing ATPase OS=Homo sapiens OX=9606 GN=NSF PE=1 SV=3 5.84 3351.5 - 283634 - - - 0.205 - 1.915 0.301 - 225.5 1 2 0 0.0002 10 0 0 0 3.27E+07 1.93E+07 - - - 3.0777 0.9794 221125_WJC_METTL3_EV_vs_WT_F01.16714.16714.2 0.751 14-Jun R.TFLVPEIK.S sp|Q9P1Y5|CAMP3_HUMAN 1 945.5535 44.66 4737 16714 2 945.552692 473.784 Calmodulin-regulated spectrin-associated protein 3 OS=Homo sapiens OX=9606 GN=CAMSAP3 PE=1 SV=2 5.66 3352.8 - 369886 - - - -0.8746 - 1.103 0.12 - 97.6 1 2 0 -0.0008 8 0 0 0 7.03E+06 1.58E+05 - - - 0.2227 0.9996 221125_WJC_METTL3_EV_vs_WT_F01.16716.16716.2 0.000222 14-Aug K.MVGFIIGR[166.11].G "sp|Q96I24|FUBP3_HUMAN,sp|Q96AE4|FUBP1_HUMAN,tr|E9PEB5|E9PEB5_HUMAN,tr|C9JSZ1|C9JSZ1_HUMAN" 4 901.5083 1.59 4738 16716 2 901.506154 451.7614 Far upstream element-binding protein 3 OS=Homo sapiens OX=9606 GN=FUBP3 PE=1 SV=2 9.5 3353 - 6.88E+07 - - - -2.396 - 1.751 0.508 - 233.3 1 2 0 -0.0022 8 0 0 0 2.63E+09 1.65E+09 - - - 4.4819 0.9988 221125_WJC_METTL3_EV_vs_WT_F01.16718.16718.2 0.00329 18-Oct R.LGGIGQFLAK[136.11].A sp|Q08211|DHX9_HUMAN 1 1010.6004 0.97 4739 16718 2 1010.602577 506.3075 ATP-dependent RNA helicase A OS=Homo sapiens OX=9606 GN=DHX9 PE=1 SV=4 8.75 3353.3 - 7.74E+06 - - - 2.1383 - 2.224 0.248 - 260.1 1 2 0 0.0022 10 0 0 0 3.02E+08 3.10E+08 - - - 3.1032 0.9997 221125_WJC_METTL3_EV_vs_WT_F01.16720.16720.2 0.0187 16-Oct R.LLDLELTSR[166.11].F "sp|Q9Y2Q9|RT28_HUMAN,tr|H0YAT2|H0YAT2_HUMAN,tr|E5RK86|E5RK86_HUMAN,tr|E5RGC7|E5RGC7_HUMAN,tr|E5RFH3|E5RFH3_HUMAN" 5 1068.6054 1.63 4741 16720 2 1068.603799 535.31 "28S ribosomal protein S28, mitochondrial OS=Homo sapiens OX=9606 GN=MRPS28 PE=1 SV=1" 4.37 3353.4 - 1.89E+06 - - - -1.5403 - 2.054 0.431 - 351.9 1 2 0 -0.0016 9 0 0 0 6.88E+07 4.21E+07 - - - 4.3062 0.999 221125_WJC_METTL3_EV_vs_WT_F01.16727.16727.2 0.0027 18-Aug R.LGGIGQFLAK.A sp|Q08211|DHX9_HUMAN 1 1002.5862 0.99 4746 16727 2 1002.585896 502.3004 ATP-dependent RNA helicase A OS=Homo sapiens OX=9606 GN=DHX9 PE=1 SV=4 8.75 3354.3 - 8.40E+06 - - - -0.3192 - 1.594 0.278 - 132.3 1 2 0 -0.0003 10 0 0 0 3.07E+08 3.10E+08 - - - 2.3956 0.9918 221125_WJC_METTL3_EV_vs_WT_F01.16728.16728.2 0.0277 14-Jun R.VIPLPQWK.A sp|Q96ES7|SGF29_HUMAN 1 979.5855 1.34 4747 16728 2 979.584394 490.8 SAGA-associated factor 29 OS=Homo sapiens OX=9606 GN=SGF29 PE=1 SV=1 8.72 3354.4 - 1.48E+06 - - - -1.1168 - 0.962 0.27 - 99.8 1 2 0 -0.0011 8 0 0 0 6.51E+07 4.86E+07 - - - 0.918 0.9998 221125_WJC_METTL3_EV_vs_WT_F01.16729.16729.2 0.00543 16-Oct K.LNNLVLFDK.A sp|P62851|RS25_HUMAN 1 1074.6073 1.22 4748 16729 2 1074.606843 538.3109 40S ribosomal protein S25 OS=Homo sapiens OX=9606 GN=RPS25 PE=1 SV=1 5.84 3354.5 - 829078 - - - -0.4681 - 2.381 0.349 - 265.3 1 2 0 -0.0005 9 0 0 0 6.16E+08 5.06E+08 - - - 4.1283 0.9966 221125_WJC_METTL3_EV_vs_WT_F01.16731.16731.2 0.142 16-Aug R.FGIWTGEYK[136.11].C sp|Q9NUD5|ZCHC3_HUMAN 1 1107.548 2.71 4750 16731 2 1107.54783 554.7813 Zinc finger CCHC domain-containing protein 3 OS=Homo sapiens OX=9606 GN=ZCCHC3 PE=1 SV=2 6 3354.8 - 364624 - - - -0.195 - 1.626 0.125 - 122.3 1 2 0 -0.0002 9 0 0 0 3.07E+07 1.14E+07 - - - 1.3706 0.9994 221125_WJC_METTL3_EV_vs_WT_F01.16732.16732.2 0.000317 16-Sep R.TFTNVYWMK[136.11].V sp|Q9HBH1|DEFM_HUMAN 1 1196.578 1.93 4751 16732 2 1196.579804 599.2963 "Peptide deformylase, mitochondrial OS=Homo sapiens OX=9606 GN=PDF PE=1 SV=1" 8.26 3354.9 - 356443 - - - 1.536 - 1.632 0.403 - 243.6 1 2 0 0.0018 9 0 0 0 4.98E+07 2.59E+07 - - - 3.434 0.9998 221125_WJC_METTL3_EV_vs_WT_F01.16738.16738.2 5.51E-05 14/28 K.VIIIGSGVSGLAAAR.Q "sp|O60341|KDM1A_HUMAN,tr|R4GMQ1|R4GMQ1_HUMAN" 2 1382.8245 1.43 4755 16738 2 1382.827269 692.4196 Lysine-specific histone demethylase 1A OS=Homo sapiens OX=9606 GN=KDM1A PE=1 SV=2 9.72 3355.7 - 280088 - - - 1.967 - 2.704 0.509 - 580.7 1 2 0 0.0027 15 0 0 0 1.03E+07 7.19E+06 - - - 5.2452 0.9996 221125_WJC_METTL3_EV_vs_WT_F01.16740.16740.2 0.00231 28-Dec K.VIIIGSGVSGLAAAR[166.11].Q "sp|O60341|KDM1A_HUMAN,tr|R4GMQ1|R4GMQ1_HUMAN" 2 1392.8328 1.43 4757 16740 2 1392.830352 697.4237 Lysine-specific histone demethylase 1A OS=Homo sapiens OX=9606 GN=KDM1A PE=1 SV=2 9.72 3356 - 221231 - - - -1.7712 - 2.382 0.392 - 410.5 1 2 0 -0.0025 15 0 0 0 1.03E+07 7.19E+06 - - - 4.0694 0.9998 221125_WJC_METTL3_EV_vs_WT_F01.16744.16744.2 0.000378 16-Oct K.LNNLVLFDK[136.11].A sp|P62851|RS25_HUMAN 1 1082.6215 1.22 4759 16744 2 1082.621925 542.318 40S ribosomal protein S25 OS=Homo sapiens OX=9606 GN=RPS25 PE=1 SV=1 5.84 3356.5 - 4.60E+06 - - - 0.3501 - 2.432 0.394 - 394 1 2 0 0.0004 9 0 0 0 6.16E+08 5.06E+08 - - - 4.5221 0.9995 221125_WJC_METTL3_EV_vs_WT_F01.16745.16745.2 0.0362 14-Oct R.IVEVLLMK.D "sp|O75526|RMXL2_HUMAN,sp|P38159|RBMX_HUMAN,tr|H3BT71|H3BT71_HUMAN,tr|H0Y6E7|H0Y6E7_HUMAN,tr|H3BR27|H3BR27_HUMAN" 5 943.5776 1.27 4760 16745 2 943.578084 472.7961 "RNA-binding motif protein, X-linked-like-2 OS=Homo sapiens OX=9606 GN=RBMXL2 PE=1 SV=3" 6 3356.6 - 3.32E+06 - - - 0.4864 - 2.222 0.227 - 271.9 1 2 0 0.0005 8 0 0 0 1.16E+09 9.13E+08 - - - 3.1254 0.7807 221125_WJC_METTL3_EV_vs_WT_F01.16747.16747.2 1.36 18-Jun R.AQELIENINK[136.11].S sp|Q6PIF2|SYCE2_HUMAN 1 1178.6387 0.001 4762 16747 2 1178.64366 590.3266 Synaptonemal complex central element protein 2 OS=Homo sapiens OX=9606 GN=SYCE2 PE=1 SV=2 4.53 3356.8 - 386489 - - - 4.249 - 1.153 0.082 - 74 1 2 0 0.005 10 0 0 0 0.00E+00 7.86E+06 - - - 0.0425 0.9986 221125_WJC_METTL3_EV_vs_WT_F01.16748.16748.2 0.0266 20-Oct R.LALEAEVSELR.A "sp|Q7Z406|MYH14_HUMAN,tr|A0A0C4DFM8|A0A0C4DFM8_HUMAN" 2 1228.6663 1.18 4763 16748 2 1228.668476 615.3404 Myosin-14 OS=Homo sapiens OX=9606 GN=MYH14 PE=1 SV=2 4.25 3356.9 - 184440 - - - 1.7572 - 1.877 0.26 - 209.2 1 2 0 0.0022 11 0 0 0 1.69E+06 1.44E+06 - - - 2.6641 0.9993 221125_WJC_METTL3_EV_vs_WT_F01.16752.16752.2 0.00134 14-Jul K.LFDFVNAK[136.11].K "sp|Q08945|SSRP1_HUMAN,tr|A0A0U1RRK2|A0A0U1RRK2_HUMAN" 2 960.516 0.53 4765 16752 2 960.516932 481.2653 FACT complex subunit SSRP1 OS=Homo sapiens OX=9606 GN=SSRP1 PE=1 SV=1 5.84 3357.4 - 6.07E+06 - - - 0.9516 - 1.348 0.413 - 120.2 1 2 0 0.0009 8 0 0 0 1.02E+08 1.93E+08 - - - 2.9918 0.9996 221125_WJC_METTL3_EV_vs_WT_F01.16753.16753.2 0.386 14-Oct R.IVEVLLMK[136.11].D "sp|O75526|RMXL2_HUMAN,sp|P38159|RBMX_HUMAN,tr|H3BT71|H3BT71_HUMAN,tr|H0Y6E7|H0Y6E7_HUMAN,tr|H3BR27|H3BR27_HUMAN" 5 951.5918 1.27 4766 16753 2 951.592115 476.8032 "RNA-binding motif protein, X-linked-like-2 OS=Homo sapiens OX=9606 GN=RBMXL2 PE=1 SV=3" 6 3357.5 - 7.10E+06 - - - 0.3048 - 2.058 0.273 - 242.7 1 2 0 0.0003 8 0 0 0 1.16E+09 9.13E+08 - - - 3.234 0.9994 221125_WJC_METTL3_EV_vs_WT_F01.16764.16764.2 0.0285 16-Sep R.LLDLELTSR.F "sp|Q9Y2Q9|RT28_HUMAN,tr|H0YAT2|H0YAT2_HUMAN,tr|E5RK86|E5RK86_HUMAN,tr|E5RGC7|E5RGC7_HUMAN,tr|E5RFH3|E5RFH3_HUMAN" 5 1058.5972 1.63 4775 16764 2 1058.597329 530.3059 "28S ribosomal protein S28, mitochondrial OS=Homo sapiens OX=9606 GN=MRPS28 PE=1 SV=1" 4.37 3358.6 - 2.37E+06 - - - 0.1455 - 1.875 0.277 - 230.7 1 2 0 0.0002 9 0 0 0 6.88E+07 4.21E+07 - - - 2.9055 0.9796 221125_WJC_METTL3_EV_vs_WT_F01.16767.16767.2 0.0072 16-Oct D.IPIILVGNK[136.11].S "sp|P55040|GEM_HUMAN,sp|Q8IXI2|MIRO1_HUMAN,tr|H7BXZ6|H7BXZ6_HUMAN" 3 973.6416 0.82 4778 16767 2 973.641418 487.8281 GTP-binding protein GEM OS=Homo sapiens OX=9606 GN=GEM PE=1 SV=1 8.75 3358.9 - 539873 - - - -0.1387 - 2.255 0.272 - 290.6 1 1 0 -0.0001 9 0 0 0 8.08E+06 9.90E+06 - - - 3.4024 0.9992 221125_WJC_METTL3_EV_vs_WT_F01.16776.16776.2 0.00133 18-Nov K.VALDLDPYVK.K sp|O95295|SNAPN_HUMAN 1 1131.6176 0.93 4785 16776 2 1131.621222 566.8161 SNARE-associated protein Snapin OS=Homo sapiens OX=9606 GN=SNAPIN PE=1 SV=1 4.21 3360.1 - 228103 - - - 3.2219 - 2.123 0.454 - 374.5 1 2 0 0.0036 10 0 0 0 3.62E+07 3.91E+07 - - - 4.4945 0.9995 221125_WJC_METTL3_EV_vs_WT_F01.16780.16780.2 0.000822 20-Sep R.LYPVLQQSLVR[166.11].A sp|Q5RKV6|EXOS6_HUMAN 1 1324.7742 1 4786 16780 2 1324.775262 663.3944 Exosome complex component MTR3 OS=Homo sapiens OX=9606 GN=EXOSC6 PE=1 SV=1 8.75 3360.7 - 344973 - - - 0.7699 - 1.658 0.392 - 203.2 1 2 0 0.001 11 0 0 0 9.64E+06 9.60E+06 - - - 3.3038 0.9989 221125_WJC_METTL3_EV_vs_WT_F01.16785.16785.2 0.00243 14-Aug R.SAVFLSFK[136.11].S sp|Q96JM7|LMBL3_HUMAN 1 905.5102 1.11 4789 16785 2 905.512167 453.7624 Lethal(3)malignant brain tumor-like protein 3 OS=Homo sapiens OX=9606 GN=L3MBTL3 PE=1 SV=2 8.47 3361.4 - 685619 - - - 2.1678 - 1.675 0.354 - 211.4 1 2 0 0.002 8 0 0 0 1.19E+07 1.08E+07 - - - 3.2107 0.9617 221125_WJC_METTL3_EV_vs_WT_F01.16790.16790.2 15.7 14-Jul K.LIEPFFNK[136.11].L "sp|O95453|PARN_HUMAN,tr|A0A494C0Q6|A0A494C0Q6_HUMAN,tr|A0A494BZW7|A0A494BZW7_HUMAN,tr|A0A494C0Q2|A0A494C0Q2_HUMAN,tr|A0A494BZU6|A0A494BZU6_HUMAN,tr|A0A494C1G3|A0A494C1G3_HUMAN,tr|A0A494C1K5|A0A494C1K5_HUMAN,tr|A0A494C156|A0A494C156_HUMAN,tr|A0A494C1N1|A0A494C1N1_HUMAN,tr|A0A494C0W0|A0A494C0W0_HUMAN,tr|A0A494C0P9|A0A494C0P9_HUMAN,tr|A0A494C0K5|A0A494C0K5_HUMAN,tr|H3BRK1|H3BRK1_HUMAN" 13 1014.563 0.6 4792 16790 2 1014.563696 508.2888 Poly(A)-specific ribonuclease PARN OS=Homo sapiens OX=9606 GN=PARN PE=1 SV=1 6 3361.9 - 2.80E+06 - - - 0.7176 - 1.239 0.02 - 111.1 1 2 0 0.0007 8 0 0 0 4.06E+07 6.73E+07 - - - -0.1652 0.9996 221125_WJC_METTL3_EV_vs_WT_F01.16795.16795.2 0.000165 24-Oct K.LLLGAGAVAYGVR[166.11].E "sp|Q99623|PHB2_HUMAN,tr|F5H3X6|F5H3X6_HUMAN,tr|A0A7I2V5F0|A0A7I2V5F0_HUMAN,tr|F5GWA7|F5GWA7_HUMAN,tr|J3KPX7|J3KPX7_HUMAN,tr|F5GY37|F5GY37_HUMAN,tr|A0A3G2KQ93|A0A3G2KQ93_HUMAN,tr|F5H2D2|F5H2D2_HUMAN,tr|F5H0C5|F5H0C5_HUMAN" 9 1268.748 1.1 4795 16795 2 1268.745115 635.3813 Prohibitin-2 OS=Homo sapiens OX=9606 GN=PHB2 PE=1 SV=2 8.75 3362.6 - 248593 - - - -2.2952 - 2.079 0.478 - 267.4 1 2 0 -0.0029 13 0 0 0 1.55E+08 1.41E+08 - - - 4.449 0.9958 221125_WJC_METTL3_EV_vs_WT_F01.16797.16797.2 0.0367 26-Sep R.LGGIPVGVVAVETR[166.11].T "sp|Q13085|ACACA_HUMAN,tr|Q59FY4|Q59FY4_HUMAN" 2 1375.8063 0.73 4797 16797 2 1375.803631 688.9104 Acetyl-CoA carboxylase 1 OS=Homo sapiens OX=9606 GN=ACACA PE=1 SV=2 6 3362.9 - 171825 - - - -1.9181 - 1.47 0.238 - 170.6 1 2 0 -0.0026 14 0 0 0 4.14E+06 5.70E+06 - - - 1.7648 0.9964 221125_WJC_METTL3_EV_vs_WT_F01.16799.16799.2 0.00257 20-Jul R.LYPVLQQSLVR.A sp|Q5RKV6|EXOS6_HUMAN 1 1314.766 0.99 4798 16799 2 1314.769652 658.3903 Exosome complex component MTR3 OS=Homo sapiens OX=9606 GN=EXOSC6 PE=1 SV=1 8.75 3363.1 - 374143 - - - 2.799 - 1.431 0.33 - 153.7 1 2 0 0.0037 11 0 0 0 1.01E+07 1.02E+07 - - - 2.4467 0.9995 221125_WJC_METTL3_EV_vs_WT_F01.16801.16801.2 0.00957 18-Oct K.VALDLDPYVK[136.11].K sp|O95295|SNAPN_HUMAN 1 1139.6318 0.9 4799 16801 2 1139.629974 570.8232 SNARE-associated protein Snapin OS=Homo sapiens OX=9606 GN=SNAPIN PE=1 SV=1 4.21 3363.3 - 972441 - - - -1.5812 - 1.902 0.377 - 304.4 1 2 0 -0.0018 10 0 0 0 3.54E+07 3.93E+07 - - - 3.6195 0.9974 221125_WJC_METTL3_EV_vs_WT_F01.16803.16803.2 0.127 12-Jun K.VSMDWLR.L "sp|Q92540|SMG7_HUMAN,tr|E9PD50|E9PD50_HUMAN,tr|B1ALB4|B1ALB4_HUMAN" 3 905.4429 0.96 4801 16803 2 905.443661 453.7287 Protein SMG7 OS=Homo sapiens OX=9606 GN=SMG7 PE=1 SV=2 5.81 3363.5 - 484222 - - - 0.8151 - 1.508 0.188 - 104.4 1 2 0 0.0007 7 0 0 0 1.13E+07 1.18E+07 - - - 1.7309 0.9998 221125_WJC_METTL3_EV_vs_WT_F01.16804.16804.2 0.00032 24-Nov K.LLLGAGAVAYGVR.E "sp|Q99623|PHB2_HUMAN,tr|F5H3X6|F5H3X6_HUMAN,tr|A0A7I2V5F0|A0A7I2V5F0_HUMAN,tr|F5GWA7|F5GWA7_HUMAN,tr|J3KPX7|J3KPX7_HUMAN,tr|F5GY37|F5GY37_HUMAN,tr|A0A3G2KQ93|A0A3G2KQ93_HUMAN,tr|F5H2D2|F5H2D2_HUMAN,tr|F5H0C5|F5H0C5_HUMAN" 9 1258.7398 1.08 4802 16804 2 1258.741447 630.3772 Prohibitin-2 OS=Homo sapiens OX=9606 GN=PHB2 PE=1 SV=2 8.75 3363.7 - 409046 - - - 1.3426 - 2.161 0.468 - 429.3 1 2 0 0.0017 13 0 0 0 1.57E+08 1.45E+08 - - - 4.4748 0.9998 221125_WJC_METTL3_EV_vs_WT_F01.16810.16810.2 0.000473 18-Nov R.VLISTDVWAR.G "sp|P38919|IF4A3_HUMAN,tr|I3L3H2|I3L3H2_HUMAN" 2 1158.6397 1.55 4807 16810 2 1158.639973 580.3271 Eukaryotic initiation factor 4A-III OS=Homo sapiens OX=9606 GN=EIF4A3 PE=1 SV=4 5.81 3364.4 - 1.68E+07 - - - 0.2287 - 2.218 0.402 - 497.4 1 2 0 0.0003 10 0 0 0 6.00E+08 3.88E+08 - - - 4.2337 0.9998 221125_WJC_METTL3_EV_vs_WT_F01.16811.16811.2 0.00122 18-Oct R.VLISTDVWAR[166.11].G "sp|P38919|IF4A3_HUMAN,tr|I3L3H2|I3L3H2_HUMAN" 2 1168.648 1.55 4808 16811 2 1168.648064 585.3313 Eukaryotic initiation factor 4A-III OS=Homo sapiens OX=9606 GN=EIF4A3 PE=1 SV=4 5.81 3364.4 - 9.19E+06 - - - 0.0736 - 2.141 0.422 - 312.4 1 2 0 0.0001 10 0 0 0 6.00E+08 3.88E+08 - - - 4.2828 0.9573 221125_WJC_METTL3_EV_vs_WT_F01.16812.16812.2 0.0467 22-Jun R.IINEPTAAAIAY.G "sp|P11021|BIP_HUMAN,sp|P54652|HSP72_HUMAN,sp|P0DMV8|HS71A_HUMAN,sp|P34931|HS71L_HUMAN,sp|P11142|HSP7C_HUMAN,sp|P0DMV9|HS71B_HUMAN,sp|P17066|HSP76_HUMAN,tr|E9PKE3|E9PKE3_HUMAN,tr|E9PN89|E9PN89_HUMAN,tr|A0A7P0TB36|A0A7P0TB36_HUMAN,tr|E9PLF4|E9PLF4_HUMAN,tr|A0A7P0TAI0|A0A7P0TAI0_HUMAN,tr|Q53FA3|Q53FA3_HUMAN,tr|E9PI65|E9PI65_HUMAN,tr|E9PK54|E9PK54_HUMAN,tr|A0A0G2JIW1|A0A0G2JIW1_HUMAN" 16 1245.6605 - 4809 16812 2 1245.661008 623.8375 Endoplasmic reticulum chaperone BiP OS=Homo sapiens OX=9606 GN=HSPA5 PE=1 SV=2 4 3364.5 - 1.20E+07 - - - 0.4046 - 1.469 0.358 - 98.4 1 1 0 0.0005 12 0 0 0 - - - - - 2.6969 0.9982 221125_WJC_METTL3_EV_vs_WT_F01.16813.16813.2 0.226 16-Jul R.IELLIDAAR[166.11].Q sp|Q8IU81|I2BP1_HUMAN 1 1022.6 1.22 4810 16813 2 1022.600435 512.3073 Interferon regulatory factor 2-binding protein 1 OS=Homo sapiens OX=9606 GN=IRF2BP1 PE=1 SV=1 4.37 3364.5 - 2.89E+06 - - - 0.4586 - 1.907 0.137 - 187.6 1 2 0 0.0005 9 0 0 0 5.32E+07 4.35E+07 - - - 1.9203 0.9997 221125_WJC_METTL3_EV_vs_WT_F01.16816.16816.2 0.00525 18-Aug R.LLGPC[160.03]MDIMK.R "sp|P13861|KAP2_HUMAN,tr|H7C330|H7C330_HUMAN" 2 1176.5705 1.72 4813 16816 2 1176.570218 589.2925 cAMP-dependent protein kinase type II-alpha regulatory subunit OS=Homo sapiens OX=9606 GN=PRKAR2A PE=1 SV=2 5.83 3364.8 - 333350 - - - -0.2465 - 1.635 0.422 - 136 1 2 0 -0.0003 10 0 0 0 9.91E+06 5.77E+06 - - - 3.5301 0.9999 221125_WJC_METTL3_EV_vs_WT_F01.16817.16817.2 0.000131 26-Nov R.LGGIPVGVVAVETR.T "sp|Q13085|ACACA_HUMAN,tr|Q59FY4|Q59FY4_HUMAN" 2 1365.798 0.73 4814 16817 2 1365.796792 683.9063 Acetyl-CoA carboxylase 1 OS=Homo sapiens OX=9606 GN=ACACA PE=1 SV=2 6 3365 - 258389 - - - -0.8845 - 1.885 0.557 - 310.1 1 2 0 -0.0012 14 0 0 0 4.14E+06 5.70E+06 - - - 4.7454 0.9964 221125_WJC_METTL3_EV_vs_WT_F01.16818.16818.2 0.0165 22-Aug -.MVPPVQVSPLIK.L sp|P56385|ATP5I_HUMAN 1 1306.7683 1.99 4815 16818 2 1306.770745 654.3914 "ATP synthase subunit e, mitochondrial OS=Homo sapiens OX=9606 GN=ATP5ME PE=1 SV=2" 8.5 3365.1 - 255210 - - - 1.8863 - 1.497 0.248 - 106.4 1 2 0 0.0025 12 0 0 0 1.23E+07 6.19E+06 - - - 1.9335 0.9796 221125_WJC_METTL3_EV_vs_WT_F01.16824.16824.2 0.119 18-Aug R.LAEVWMDEYK.E "sp|Q14435|GALT3_HUMAN,tr|E7EUL0|E7EUL0_HUMAN,tr|C9J2C3|C9J2C3_HUMAN" 3 1282.5904 1.79 4819 16824 2 1282.585603 642.3025 Polypeptide N-acetylgalactosaminyltransferase 3 OS=Homo sapiens OX=9606 GN=GALNT3 PE=1 SV=2 4.14 3365.9 - 255068 - - - -3.7206 - 1.593 0.164 - 210.5 1 2 0 -0.0048 10 0 0 0 3.35E+06 1.87E+06 - - - 1.5505 0.9999 221125_WJC_METTL3_EV_vs_WT_F01.16831.16831.2 6.94E-07 20-Sep R.IENVVLVVPVK.T "sp|Q9NQW7|XPP1_HUMAN,tr|Q5T6H7|Q5T6H7_HUMAN" 2 1207.754 1.7 4824 16831 2 1207.754761 604.8843 Xaa-Pro aminopeptidase 1 OS=Homo sapiens OX=9606 GN=XPNPEP1 PE=1 SV=3 6 3366.7 - 551486 - - - 0.6218 - 2.088 0.551 - 204.8 1 2 0 0.0008 11 0 0 0 1.25E+07 7.34E+06 - - - 5.1021 0.9818 221125_WJC_METTL3_EV_vs_WT_F01.16832.16832.2 0.159 12-Jun K.TSFFLVR[166.11].E sp|Q8TDD1|DDX54_HUMAN 1 878.489 0.61 4825 16832 2 878.486787 440.2518 ATP-dependent RNA helicase DDX54 OS=Homo sapiens OX=9606 GN=DDX54 PE=1 SV=2 9.41 3366.9 - 256438 - - - -2.4724 - 1.204 0.181 - 108.3 1 2 0 -0.0022 7 0 0 0 2.17E+06 3.56E+06 - - - 0.9654 0.999 221125_WJC_METTL3_EV_vs_WT_F01.16833.16833.2 0.0045 24-Oct R.SLLVNPEGPTLMR[166.11].L "sp|P49327|FAS_HUMAN,tr|A0A0U1RQF0|A0A0U1RQF0_HUMAN" 2 1435.7733 0.73 4826 16833 2 1435.775141 718.8939 Fatty acid synthase OS=Homo sapiens OX=9606 GN=FASN PE=1 SV=3 5.72 3367 - 235970 - - - 1.3136 - 2.059 0.255 - 359.7 1 2 0 0.0019 13 0 0 0 1.33E+07 1.83E+07 - - - 2.7774 0.9949 221125_WJC_METTL3_EV_vs_WT_F01.16834.16834.2 2.97E-05 22-Nov R.IVPGQFLAVDPK.G sp|Q15393|SF3B3_HUMAN 1 1282.7285 1.18 4827 16834 2 1282.735915 642.3715 Splicing factor 3B subunit 3 OS=Homo sapiens OX=9606 GN=SF3B3 PE=1 SV=4 5.84 3367.1 - 223814 - - - 5.7619 - 1.979 0.49 - 274.7 1 2 0 0.0074 12 0 0 0 6.22E+07 5.29E+07 - - - 4.4538 0.9999 221125_WJC_METTL3_EV_vs_WT_F01.16837.16837.3 3.07E-06 13/48 K.LLLGAGAVAYGVR.E "sp|Q99623|PHB2_HUMAN,tr|F5H3X6|F5H3X6_HUMAN,tr|A0A7I2V5F0|A0A7I2V5F0_HUMAN,tr|F5GWA7|F5GWA7_HUMAN,tr|J3KPX7|J3KPX7_HUMAN,tr|F5GY37|F5GY37_HUMAN,tr|A0A3G2KQ93|A0A3G2KQ93_HUMAN,tr|F5H2D2|F5H2D2_HUMAN,tr|F5H0C5|F5H0C5_HUMAN" 9 1258.7398 1.07 4828 16837 3 1258.739877 420.5872 Prohibitin-2 OS=Homo sapiens OX=9606 GN=PHB2 PE=1 SV=2 8.75 3367.5 - 855640 - - - 0.0953 - 2.36 0.443 - 213.9 1 2 0 0.0001 13 0 0 0 1.62E+07 1.51E+07 - - - 5.8071 0.9997 221125_WJC_METTL3_EV_vs_WT_F01.16839.16839.2 0.00165 22-Sep R.IVPGQFLAVDPK[136.11].G sp|Q15393|SF3B3_HUMAN 1 1290.7427 1.18 4830 16839 2 1290.743594 646.3786 Splicing factor 3B subunit 3 OS=Homo sapiens OX=9606 GN=SF3B3 PE=1 SV=4 5.84 3367.8 - 395590 - - - 0.674 - 1.82 0.419 - 184.9 1 2 0 0.0009 12 0 0 0 6.22E+07 5.29E+07 - - - 3.7111 0.9997 221125_WJC_METTL3_EV_vs_WT_F01.16849.16849.2 4.54E-05 24-Oct R.SLLVNPEGPTLMR.L "sp|P49327|FAS_HUMAN,tr|A0A0U1RQF0|A0A0U1RQF0_HUMAN" 2 1425.765 0.73 4839 16849 2 1425.767072 713.8898 Fatty acid synthase OS=Homo sapiens OX=9606 GN=FASN PE=1 SV=3 5.72 3368.9 - 259234 - - - 1.4638 - 2.144 0.459 - 314.6 1 2 0 0.0021 13 0 0 0 1.33E+07 1.83E+07 - - - 4.3879 1 221125_WJC_METTL3_EV_vs_WT_F01.16850.16850.2 5.09E-08 14/22 R.MSVDAVEIETLR.K "sp|P78347|GTF2I_HUMAN,tr|A0A494C1K3|A0A494C1K3_HUMAN" 2 1361.6861 1.76 4840 16850 2 1361.689178 681.8503 General transcription factor II-I OS=Homo sapiens OX=9606 GN=GTF2I PE=1 SV=2 4.14 3369.1 - 207154 - - - 2.2854 - 2.862 0.557 - 738.6 1 2 0 0.0031 12 0 0 0 7.25E+06 4.11E+06 - - - 5.9208 0.9996 221125_WJC_METTL3_EV_vs_WT_F01.16855.16855.2 0.00189 18-Sep K.VVDLLAPYAK[136.11].G "sp|P06576|ATPB_HUMAN,tr|F8W079|F8W079_HUMAN,tr|H0YH81|H0YH81_HUMAN" 3 1095.6419 1.88 4843 16855 2 1095.642821 548.8282 "ATP synthase subunit beta, mitochondrial OS=Homo sapiens OX=9606 GN=ATP5F1B PE=1 SV=3" 5.81 3369.7 - 6.21E+06 - - - 0.7977 - 1.82 0.39 - 215.8 1 2 0 0.0009 10 0 0 0 1.41E+09 7.47E+08 - - - 3.5928 0.9987 221125_WJC_METTL3_EV_vs_WT_F01.16856.16856.2 0.149 14-Jul R.EFDMILGK[136.11].L "sp|Q8N1F7|NUP93_HUMAN,tr|H3BVG0|H3BVG0_HUMAN" 2 959.4878 2.06 4844 16856 2 959.488223 480.7512 Nuclear pore complex protein Nup93 OS=Homo sapiens OX=9606 GN=NUP93 PE=1 SV=2 4.37 3369.8 - 852316 - - - 0.4888 - 1.277 0.327 - 157.8 1 2 0 0.0005 8 0 0 0 2.47E+07 1.20E+07 - - - 2.1935 0.9866 221125_WJC_METTL3_EV_vs_WT_F01.16857.16857.2 0.0395 18-Nov M.ALDIEIATYR.K "sp|P08670|VIME_HUMAN,sp|P14136|GFAP_HUMAN,sp|Q6KB66|K2C80_HUMAN,sp|P05787|K2C8_HUMAN,sp|P41219|PERI_HUMAN,sp|P19013|K2C4_HUMAN,sp|P04264|K2C1_HUMAN,sp|P08729|K2C7_HUMAN,tr|A0A1W2PR46|A0A1W2PR46_HUMAN,tr|H7C5W5|H7C5W5_HUMAN,tr|A0A1X7SBR3|A0A1X7SBR3_HUMAN,tr|A0A1W2PQU7|A0A1W2PQU7_HUMAN,tr|K7EJU1|K7EJU1_HUMAN,tr|A0A1X7SCE1|A0A1X7SCE1_HUMAN,tr|A0A1W2PRT3|A0A1W2PRT3_HUMAN,tr|A0A1W2PS58|A0A1W2PS58_HUMAN,tr|B0YJC5|B0YJC5_HUMAN,tr|B0YJC4|B0YJC4_HUMAN,tr|K7EPI4|K7EPI4_HUMAN,tr|K7EPT8|K7EPT8_HUMAN" 20 1163.6186 59.35 4845 16857 2 1163.619326 582.8166 Vimentin OS=Homo sapiens OX=9606 GN=VIM PE=1 SV=4 4.37 3369.9 - 1.02E+06 - - - 0.5904 - 2.27 0.372 - 565.8 1 1 0 0.0007 10 0 0 0 1.50E+07 2.53E+05 - - - 4.0766 0.9976 221125_WJC_METTL3_EV_vs_WT_F01.16858.16858.2 0.0691 16-Jun R.MLPPPPMWR[166.11].R "sp|Q15287|RNPS1_HUMAN,tr|H3BMM9|H3BMM9_HUMAN,tr|H3BV80|H3BV80_HUMAN,tr|H3BTC0|H3BTC0_HUMAN,tr|H3BPG5|H3BPG5_HUMAN" 5 1133.5753 1.06 4846 16858 2 1133.577182 567.795 RNA-binding protein with serine-rich domain 1 OS=Homo sapiens OX=9606 GN=RNPS1 PE=1 SV=1 9.5 3370 - 950668 - - - 1.6179 - 1.251 0.332 - 157.6 1 2 0 0.0018 9 0 0 0 2.10E+07 1.98E+07 - - - 2.1405 0.9994 221125_WJC_METTL3_EV_vs_WT_F01.16864.16864.2 0.000363 22-Aug R.ILYIVASDPYSR[166.11].L "sp|Q9ULT8|HECD1_HUMAN,tr|H0YJD4|H0YJD4_HUMAN,tr|A0A087X2H1|A0A087X2H1_HUMAN,tr|H0YJP0|H0YJP0_HUMAN" 4 1405.7481 0.38 4851 16864 2 1405.750665 703.8813 E3 ubiquitin-protein ligase HECTD1 OS=Homo sapiens OX=9606 GN=HECTD1 PE=1 SV=3 5.83 3370.7 - 202339 - - - 1.8339 - 1.867 0.399 - 231.2 1 2 0 0.0026 12 0 0 0 2.48E+06 6.49E+06 - - - 3.6299 0.9985 221125_WJC_METTL3_EV_vs_WT_F01.16867.16867.2 0.0645 14-Jun R.EFDMILGK.L "sp|Q8N1F7|NUP93_HUMAN,tr|H3BVG0|H3BVG0_HUMAN" 2 951.4736 2.09 4854 16867 2 951.474546 476.7441 Nuclear pore complex protein Nup93 OS=Homo sapiens OX=9606 GN=NUP93 PE=1 SV=2 4.37 3370.9 - 1.96E+06 - - - 1.0426 - 1.284 0.335 - 123.5 1 2 0 0.001 8 0 0 0 2.50E+07 1.20E+07 - - - 2.2689 1 221125_WJC_METTL3_EV_vs_WT_F01.16871.16871.2 4.47E-07 22-Oct R.MSVDAVEIETLR[166.11].K "sp|P78347|GTF2I_HUMAN,tr|A0A494C1K3|A0A494C1K3_HUMAN" 2 1371.6943 1.79 4858 16871 2 1371.692252 686.8544 General transcription factor II-I OS=Homo sapiens OX=9606 GN=GTF2I PE=1 SV=2 4.14 3371.4 - 349536 - - - -1.5193 - 2.589 0.574 - 413.7 1 2 0 -0.0021 12 0 0 0 7.38E+06 4.11E+06 - - - 5.7829 0.9929 221125_WJC_METTL3_EV_vs_WT_F01.16874.16874.2 0.32 14-Aug R.AYILNLVK.Q sp|P50991|TCPD_HUMAN 1 932.5695 0.32 4860 16874 2 932.570413 467.292 T-complex protein 1 subunit delta OS=Homo sapiens OX=9606 GN=CCT4 PE=1 SV=4 8.63 3371.8 - 3.38E+06 - - - 0.9747 - 1.188 0.201 - 212.6 1 2 0 0.0009 8 0 0 0 1.98E+08 6.10E+08 - - - 1.0449 0.9998 221125_WJC_METTL3_EV_vs_WT_F01.16876.16876.2 0.00155 18-Dec K.WVGVILDEAK.G "sp|Q14203|DCTN1_HUMAN,tr|C9JTE5|C9JTE5_HUMAN,tr|A0A804CDA6|A0A804CDA6_HUMAN,tr|C9JJN7|C9JJN7_HUMAN,tr|E7EX90|E7EX90_HUMAN,tr|C9JJD0|C9JJD0_HUMAN,tr|A0A7P0Z4C3|A0A7P0Z4C3_HUMAN,tr|Q6AWB1|Q6AWB1_HUMAN,tr|C9JZA4|C9JZA4_HUMAN,tr|E9PCY0|E9PCY0_HUMAN,tr|C9J1B7|C9J1B7_HUMAN,tr|C9JKG6|C9JKG6_HUMAN" 12 1128.6179 2.02 4862 16876 2 1128.619466 565.3162 Dynactin subunit 1 OS=Homo sapiens OX=9606 GN=DCTN1 PE=1 SV=3 4.37 3371.9 - 3.36E+06 - - - 1.3787 - 2.275 0.445 - 502.4 1 2 0 0.0016 10 0 0 0 3.07E+08 1.52E+08 - - - 4.6217 0.9973 221125_WJC_METTL3_EV_vs_WT_F01.16877.16877.2 0.956 14-Sep R.TEMDWVLK.H "sp|P52597|HNRPF_HUMAN,tr|A0A1B0GW42|A0A1B0GW42_HUMAN" 2 1020.495 0.69 4863 16877 2 1020.49566 511.2548 Heterogeneous nuclear ribonucleoprotein F OS=Homo sapiens OX=9606 GN=HNRNPF PE=1 SV=3 4.37 3371.9 - 1.23E+06 - - - 0.6291 - 1.659 0.147 - 304.3 1 2 0 0.0006 8 0 0 0 2.15E+07 3.12E+07 - - - 1.6533 0.9956 221125_WJC_METTL3_EV_vs_WT_F01.16884.16884.2 0.0832 14-Aug R.AYILNLVK[136.11].Q sp|P50991|TCPD_HUMAN 1 940.5837 0.33 4869 16884 2 940.583633 471.2991 T-complex protein 1 subunit delta OS=Homo sapiens OX=9606 GN=CCT4 PE=1 SV=4 8.63 3372.7 - 5.43E+06 - - - -0.0755 - 1.19 0.219 - 213.3 1 2 0 -0.0001 8 0 0 0 1.97E+08 6.00E+08 - - - 1.1831 0.9984 221125_WJC_METTL3_EV_vs_WT_F01.16887.16887.2 0.592 14-Jul R.TEMDWVLK[136.11].H "sp|P52597|HNRPF_HUMAN,tr|A0A1B0GW42|A0A1B0GW42_HUMAN" 2 1028.5092 0.69 4872 16887 2 1028.509568 515.2619 Heterogeneous nuclear ribonucleoprotein F OS=Homo sapiens OX=9606 GN=HNRNPF PE=1 SV=3 4.37 3372.9 - 1.98E+06 - - - 0.3403 - 1.504 0.233 - 219 1 2 0 0.0003 8 0 0 0 2.18E+07 3.15E+07 - - - 1.9927 0.8947 221125_WJC_METTL3_EV_vs_WT_F01.16892.16892.2 1.13 12-Aug N.IC[160.03]LDILK[136.11].E "sp|O00762|UBE2C_HUMAN,sp|P61086|UBE2K_HUMAN,sp|P61088|UBE2N_HUMAN,sp|Q96LR5|UB2E2_HUMAN,sp|P51965|UB2E1_HUMAN,sp|Q969T4|UB2E3_HUMAN,sp|Q92785|REQU_HUMAN,tr|F8VSD4|F8VSD4_HUMAN,tr|B7Z306|B7Z306_HUMAN,tr|R4GND1|R4GND1_HUMAN,tr|J3KMZ8|J3KMZ8_HUMAN,tr|H7C061|H7C061_HUMAN,tr|F8VQQ8|F8VQQ8_HUMAN,tr|F8VV71|F8VV71_HUMAN,tr|A0A1B0GX65|A0A1B0GX65_HUMAN,tr|A0A087X283|A0A087X283_HUMAN,tr|H0YEI1|H0YEI1_HUMAN,tr|C9J2P0|C9J2P0_HUMAN" 18 881.5136 2.95 4877 16892 2 881.513412 441.7641 Ubiquitin-conjugating enzyme E2 C OS=Homo sapiens OX=9606 GN=UBE2C PE=1 SV=1 5.83 3373.4 - 422194 - - - -0.1849 - 1.813 0.119 - 147.8 1 1 0 -0.0002 7 0 0 0 4.30E+07 1.46E+07 - - - 1.8051 0.9798 221125_WJC_METTL3_EV_vs_WT_F01.16893.16893.2 0.00204 20-Jun K.WGDAGAEYVVE.S "sp|P04406|G3P_HUMAN,tr|E7EUT5|E7EUT5_HUMAN" 2 1194.5193 - 4878 16893 2 1194.520015 598.2669 Glyceraldehyde-3-phosphate dehydrogenase OS=Homo sapiens OX=9606 GN=GAPDH PE=1 SV=3 3.91 3373.6 - 360250 - - - 0.5827 - 1.543 0.452 - 110.7 1 1 0 0.0007 11 0 0 0 - - - - - 3.5526 0.9998 221125_WJC_METTL3_EV_vs_WT_F01.16896.16896.2 8.26E-05 20-Nov R.EAMGIYISTLK[136.11].T "sp|O95433|AHSA1_HUMAN,tr|H0YJU2|H0YJU2_HUMAN,tr|G3V438|G3V438_HUMAN,tr|H0YJG7|H0YJG7_HUMAN" 4 1232.6566 1.72 4880 16896 2 1232.65557 617.3356 Activator of 90 kDa heat shock protein ATPase homolog 1 OS=Homo sapiens OX=9606 GN=AHSA1 PE=1 SV=1 6.1 3373.9 - 544181 - - - -0.8445 - 1.745 0.525 - 394.6 1 2 0 -0.001 11 0 0 0 1.85E+07 1.08E+07 - - - 4.4245 0.9998 221125_WJC_METTL3_EV_vs_WT_F01.16899.16899.2 0.00591 18-Oct R.FSNLLGTVYR.R "sp|Q15269|PWP2_HUMAN,tr|A0A0B4J2E5|A0A0B4J2E5_HUMAN,tr|C9J544|C9J544_HUMAN" 3 1168.6241 1.14 4882 16899 2 1168.623798 585.3193 Periodic tryptophan protein 2 homolog OS=Homo sapiens OX=9606 GN=PWP2 PE=2 SV=2 8.75 3374.3 - 612327 - - - -0.2225 - 1.939 0.433 - 323.7 1 2 0 -0.0003 10 0 0 0 3.23E+07 2.84E+07 - - - 4.0874 0.9982 221125_WJC_METTL3_EV_vs_WT_F01.16900.16900.2 0.0288 16-Aug K.VLGIYTFTK[136.11].R "sp|Q5T4S7|UBR4_HUMAN,tr|X6R960|X6R960_HUMAN" 2 1048.6048 1.41 4883 16900 2 1048.602737 525.3097 E3 ubiquitin-protein ligase UBR4 OS=Homo sapiens OX=9606 GN=UBR4 PE=1 SV=1 8.56 3374.4 - 240078 - - - -1.9988 - 1.746 0.256 - 131 1 2 0 -0.0021 9 0 0 0 7.96E+06 5.65E+06 - - - 2.5435 0.9816 221125_WJC_METTL3_EV_vs_WT_F01.16904.16904.2 0.71 12-May K.LLLDMYR.S "sp|Q5VTR2|BRE1A_HUMAN,sp|O60308|CE104_HUMAN,tr|A0A6Q8PH38|A0A6Q8PH38_HUMAN,tr|A0A6Q8PHR0|A0A6Q8PHR0_HUMAN,tr|A0A6Q8PGF0|A0A6Q8PGF0_HUMAN,tr|J3QLL3|J3QLL3_HUMAN,tr|A0A6Q8PH69|A0A6Q8PH69_HUMAN,tr|A0A6Q8PHE1|A0A6Q8PHE1_HUMAN,tr|Q5SR27|Q5SR27_HUMAN,tr|A0A6Q8PGB3|A0A6Q8PGB3_HUMAN,tr|A0A6Q8PFR4|A0A6Q8PFR4_HUMAN" 11 922.4946 0.75 4885 16904 2 922.496188 462.2546 E3 ubiquitin-protein ligase BRE1A OS=Homo sapiens OX=9606 GN=RNF20 PE=1 SV=2 5.84 3374.8 - 317784 - - - 1.6954 - 1.156 0.155 - 74.5 1 2 0 0.0016 7 0 0 0 7.04E+06 9.41E+06 - - - 0.6447 0.9432 221125_WJC_METTL3_EV_vs_WT_F01.16907.16907.2 3.38 16-May R.GLVGEIIKR.F "sp|P15531|NDKA_HUMAN,sp|P22392|NDKB_HUMAN,tr|Q32Q12|Q32Q12_HUMAN,tr|Q32Q12|Q32Q12_HUMAN,tr|J3KPD9|J3KPD9_HUMAN,tr|F6XY72|F6XY72_HUMAN,tr|E5RHP0|E5RHP0_HUMAN,tr|E7ERL0|E7ERL0_HUMAN,tr|C9K028|C9K028_HUMAN" 9 983.6128 0.77 4888 16907 2 983.610994 492.8137 Nucleoside diphosphate kinase A OS=Homo sapiens OX=9606 GN=NME1 PE=1 SV=1 8.75 3375.2 - 277265 - - - -1.8005 - 1.15 0.105 - 52.1 6 2 0 -0.0018 9 0 0 0 5.68E+06 7.33E+06 - - - -0.1273 0.9984 221125_WJC_METTL3_EV_vs_WT_F01.16910.16910.2 0.0128 12-Jun R.DFYFSVK.L sp|Q9NY12|GAR1_HUMAN 1 904.4331 1.12 4889 16910 2 904.432819 453.2238 H\ACA ribonucleoprotein complex subunit 1 OS=Homo sapiens OX=9606 GN=GAR1 PE=1 SV=1 5.83 3375.6 - 2.37E+06 - - - -0.2775 - 1.171 0.327 - 152 1 2 0 -0.0003 7 0 0 0 1.24E+08 1.11E+08 - - - 1.9563 0.9999 221125_WJC_METTL3_EV_vs_WT_F01.16913.16913.2 1.90E-05 22-Dec R.YVVGVLEAAGVR.Y sp|Q9H9S5|FKRP_HUMAN 1 1231.6925 0.61 4892 16913 2 1231.692929 616.8535 Fukutin-related protein OS=Homo sapiens OX=9606 GN=FKRP PE=1 SV=1 6 3375.9 - 607461 - - - 0.371 - 2.372 0.562 - 495.8 1 2 0 0.0005 12 0 0 0 1.21E+07 1.99E+07 - - - 5.4644 0.9995 221125_WJC_METTL3_EV_vs_WT_F01.16917.16917.2 0.00595 14-Sep R.VDEIIWVK[136.11].T sp|Q86U44|MTA70_HUMAN 1 1008.5735 0 4895 16917 2 1008.574272 505.294 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 4.37 3376.4 - 3.49E+06 - - - 0.7327 - 2.089 0.252 - 282.6 1 2 0 0.0007 8 0 0 0 3.81E+04 9.66E+07 - - - 3.1238 0.9998 221125_WJC_METTL3_EV_vs_WT_F01.16924.16924.2 0.000745 18-Oct R.LLFNDVQTLK[136.11].D "sp|Q15149|PLEC_HUMAN,tr|E9PMV1|E9PMV1_HUMAN,tr|H0YDN1|H0YDN1_HUMAN" 3 1197.6849 1.45 4900 16924 2 1197.683396 599.8497 Plectin OS=Homo sapiens OX=9606 GN=PLEC PE=1 SV=3 5.84 3377.1 - 866297 - - - -1.234 - 2.142 0.432 - 260.6 1 2 0 -0.0015 10 0 0 0 5.00E+07 3.44E+07 - - - 4.3575 0.9757 221125_WJC_METTL3_EV_vs_WT_F01.16925.16925.2 0.016 20-Jul K.ALVMYSNLDLK[136.11].T sp|O95900|TRUB2_HUMAN 1 1273.6832 0.76 4901 16925 2 1273.687909 637.8489 Mitochondrial mRNA pseudouridine synthase TRUB2 OS=Homo sapiens OX=9606 GN=TRUB2 PE=1 SV=1 5.88 3377.3 - 241527 - - - 3.7286 - 1.697 0.149 - 138.2 2 2 0 0.0047 11 0 0 0 2.98E+06 3.91E+06 - - - 1.4362 0.9923 221125_WJC_METTL3_EV_vs_WT_F01.16927.16927.2 0.881 12-Jun R.DILVAFK.G sp|Q6NUJ1|SAPL1_HUMAN 1 804.4745 7.49 4902 16927 2 804.474111 403.2445 Proactivator polypeptide-like 1 OS=Homo sapiens OX=9606 GN=PSAPL1 PE=2 SV=2 5.84 3377.5 - 363909 - - - -0.5345 - 1.206 0.161 - 149.4 1 2 0 -0.0004 7 0 0 0 6.97E+06 9.31E+05 - - - 0.8235 0.9648 221125_WJC_METTL3_EV_vs_WT_F01.16930.16930.2 1.28 12-May K.GWDPYVG.- "sp|Q9H3G5|CPVL_HUMAN,tr|H7C218|H7C218_HUMAN,tr|H7C0X5|H7C0X5_HUMAN" 3 792.3443 - 4904 16930 2 792.344382 397.1794 Probable serine carboxypeptidase CPVL OS=Homo sapiens OX=9606 GN=CPVL PE=1 SV=2 3.8 3377.8 - 281372 - - - 0.1603 - 0.837 0.179 - 68.7 1 2 0 0.0001 7 0 0 0 - - - - - -0.2007 0.9997 221125_WJC_METTL3_EV_vs_WT_F01.16931.16931.2 0.0203 16-Oct R.LSNIFVIGK[136.11].G sp|P62701|RS4X_HUMAN 1 997.6052 0.95 4905 16931 2 997.606119 499.8099 "40S ribosomal protein S4, X isoform OS=Homo sapiens OX=9606 GN=RPS4X PE=1 SV=2" 8.75 3377.9 - 2.25E+06 - - - 0.9543 - 2.095 0.397 - 279.8 1 2 0 0.001 9 0 0 0 1.37E+09 1.44E+09 - - - 4.1125 0.9998 221125_WJC_METTL3_EV_vs_WT_F01.16932.16932.2 5.69E-05 18-Oct K.VVDDEIYYFR[166.11].K "sp|Q86U86|PB1_HUMAN,tr|E7EVG2|E7EVG2_HUMAN" 2 1327.6324 1.52 4906 16932 2 1327.633042 664.8235 Protein polybromo-1 OS=Homo sapiens OX=9606 GN=PBRM1 PE=1 SV=1 4.03 3377.9 - 2.23E+06 - - - 0.4926 - 2.078 0.451 - 331.6 1 2 0 0.0007 10 0 0 0 1.05E+08 6.95E+07 - - - 4.4135 0.9999 221125_WJC_METTL3_EV_vs_WT_F01.16934.16934.2 2.10E-06 13/22 K.ISEIEDAAFLAR[166.11].E "sp|O94905|ERLN2_HUMAN,sp|O75477|ERLN1_HUMAN,tr|E5RHW4|E5RHW4_HUMAN,tr|B0QZ43|B0QZ43_HUMAN" 4 1343.6961 1.33 4908 16934 2 1343.695226 672.8553 Erlin-2 OS=Homo sapiens OX=9606 GN=ERLIN2 PE=1 SV=1 4.14 3378.2 - 167624 - - - -0.614 - 2.651 0.441 - 559 1 2 0 -0.0008 12 0 0 0 1.79E+07 1.35E+07 - - - 4.8632 0.9983 221125_WJC_METTL3_EV_vs_WT_F01.16937.16937.2 0.0469 12-Jun R.DFYFSVK[136.11].L sp|Q9NY12|GAR1_HUMAN 1 912.4473 1.12 4909 16937 2 912.447598 457.2309 H\ACA ribonucleoprotein complex subunit 1 OS=Homo sapiens OX=9606 GN=GAR1 PE=1 SV=1 5.83 3378.6 - 6.17E+06 - - - 0.3595 - 1.215 0.315 - 156.2 1 2 0 0.0003 7 0 0 0 1.24E+08 1.11E+08 - - - 1.9845 0.9824 221125_WJC_METTL3_EV_vs_WT_F01.16941.16941.2 0.00119 26-Sep L.FVGGGIGGTILYAK[136.11].W "sp|Q16891|MIC60_HUMAN,tr|B9A067|B9A067_HUMAN,tr|A0A087WYS0|A0A087WYS0_HUMAN,tr|D6RAW4|D6RAW4_HUMAN" 4 1359.7642 1.21 4913 16941 2 1359.766311 680.8894 MICOS complex subunit MIC60 OS=Homo sapiens OX=9606 GN=IMMT PE=1 SV=1 8.59 3379 - 321852 - - - 1.562 - 1.925 0.494 - 149.8 1 1 0 0.0021 14 0 0 0 2.07E+07 1.71E+07 - - - 4.3325 0.9849 221125_WJC_METTL3_EV_vs_WT_F01.16944.16944.2 0.000763 16-Jul K.LHVGYLQPL.V sp|P54709|AT1B3_HUMAN 1 1038.5862 - 4914 16944 2 1038.58648 520.3004 Sodium\potassium-transporting ATPase subunit beta-3 OS=Homo sapiens OX=9606 GN=ATP1B3 PE=1 SV=1 6.74 3379.4 - 1.28E+06 - - - 0.2542 - 1.606 0.459 - 164.1 1 1 0 0.0003 9 0 0 0 - - - - - 3.8017 0.9883 221125_WJC_METTL3_EV_vs_WT_F01.16948.16948.2 0.0287 12-Jul R.TLYFLPR[166.11].E "sp|P09884|DPOLA_HUMAN,tr|A6NMQ1|A6NMQ1_HUMAN,tr|A0A7I2V2V3|A0A7I2V2V3_HUMAN" 3 918.5203 0.78 4918 16948 2 918.523144 460.2674 DNA polymerase alpha catalytic subunit OS=Homo sapiens OX=9606 GN=POLA1 PE=1 SV=2 8.41 3379.9 - 416155 - - - 3.1409 - 1.069 0.328 - 186.9 1 2 0 0.0029 7 0 0 0 8.66E+06 1.11E+07 - - - 1.6741 0.9665 221125_WJC_METTL3_EV_vs_WT_F01.16949.16949.2 1.15E-06 26-Nov L.FVGGGIGGTILYAK.W "sp|Q16891|MIC60_HUMAN,tr|B9A067|B9A067_HUMAN,tr|A0A087WYS0|A0A087WYS0_HUMAN,tr|D6RAW4|D6RAW4_HUMAN" 4 1351.75 1.21 4919 16949 2 1351.754711 676.8823 MICOS complex subunit MIC60 OS=Homo sapiens OX=9606 GN=IMMT PE=1 SV=1 8.59 3380 - 384018 - - - 3.4947 - 2.289 0.597 - 188.6 1 1 0 0.0047 14 0 0 0 2.07E+07 1.71E+07 - - - 5.5271 0.8619 221125_WJC_METTL3_EV_vs_WT_F01.16950.16950.2 1.37 18-Jul R.TILMC[160.03]GPLIK[136.11].E "sp|Q8IZL8|PELP1_HUMAN,tr|E7EV54|E7EV54_HUMAN,tr|C9JFV4|C9JFV4_HUMAN" 3 1152.649 0.08 4920 16950 2 1152.65408 577.3318 "Proline-, glutamic acid- and leucine-rich protein 1 OS=Homo sapiens OX=9606 GN=PELP1 PE=1 SV=2" 7.89 3380.1 - 354787 - - - 4.3873 - 1.246 0.111 - 73.4 1 2 0 0.0051 10 0 0 0 5.94E+05 7.66E+06 - - - 0.4732 0.9693 221125_WJC_METTL3_EV_vs_WT_F01.16954.16954.2 0.0336 14-Aug K.MVGFIIGR.G "sp|Q96I24|FUBP3_HUMAN,sp|Q96AE4|FUBP1_HUMAN,tr|E9PEB5|E9PEB5_HUMAN,tr|C9JSZ1|C9JSZ1_HUMAN" 4 891.5 2.79 4923 16954 2 891.503991 446.7573 Far upstream element-binding protein 3 OS=Homo sapiens OX=9606 GN=FUBP3 PE=1 SV=2 9.5 3380.7 - 832824 - - - 4.4274 - 1.267 0.256 - 153.6 1 2 0 0.0039 8 0 0 0 2.71E+07 9.73E+06 - - - 1.6443 0.8005 221125_WJC_METTL3_EV_vs_WT_F01.16958.16958.2 0.354 18-Jul S.AETLTPTPER.N tr|J3KPG6|J3KPG6_HUMAN 1 1113.5666 0.64 4926 16958 2 1113.566254 557.7906 Proline-serine-threonine phosphatase-interacting protein 1 OS=Homo sapiens OX=9606 GN=PSTPIP1 PE=1 SV=1 4.53 3381.1 - 734980 - - - -0.3134 - 1.502 0.144 - 121.8 1 1 0 -0.0003 10 0 0 0 2.05E+07 3.19E+07 - - - 1.24 0.9996 221125_WJC_METTL3_EV_vs_WT_F01.16963.16963.2 0.0606 22-Dec K.VLAGVLDSVDVR[166.11].L "sp|Q8NCH0|CHSTE_HUMAN,tr|H0YN65|H0YN65_HUMAN" 2 1251.7062 12.24 4931 16963 2 1251.705162 626.8604 Carbohydrate sulfotransferase 14 OS=Homo sapiens OX=9606 GN=CHST14 PE=1 SV=2 4.21 3381.8 - 249221 - - - -0.8468 - 2.147 0.306 - 636.6 1 2 0 -0.0011 12 0 0 0 1.79E+07 1.46E+06 - - - 3.3112 0.9745 221125_WJC_METTL3_EV_vs_WT_F01.16964.16964.2 1.76 20-Jul K.MLSALLTGVNR.A sp|Q03701|CEBPZ_HUMAN 1 1173.654 0.48 4932 16964 2 1173.654879 587.8343 CCAAT\enhancer-binding protein zeta OS=Homo sapiens OX=9606 GN=CEBPZ PE=1 SV=3 9.5 3381.9 - 234028 - - - 0.7677 - 1.219 0.091 - 89.2 2 2 0 0.0009 11 0 0 0 1.82E+06 3.79E+06 - - - 0.1141 0.9645 221125_WJC_METTL3_EV_vs_WT_F01.16967.16967.2 0.00218 14-Jul D.FALPEMLK[136.11].L tr|E9PLF1|E9PLF1_HUMAN 1 955.5292 2.03 4933 16967 2 955.529723 478.7719 Glutathione S-transferase Mu 2 (Fragment) OS=Homo sapiens OX=9606 GN=GSTM2 PE=1 SV=2 6 3382.3 - 1.00E+06 - - - 0.5212 - 1.41 0.384 - 149.9 1 1 0 0.0005 8 0 0 0 1.64E+08 8.08E+07 - - - 2.9133 0.9966 221125_WJC_METTL3_EV_vs_WT_F01.16968.16968.2 2.71 14-Aug K.GLGILSLK[136.11].Q sp|Q92616|GCN1_HUMAN 1 807.5309 0.69 4934 16968 2 807.53098 404.7727 eIF-2-alpha kinase activator GCN1 OS=Homo sapiens OX=9606 GN=GCN1 PE=1 SV=6 8.75 3382.4 - 730107 - - - 0.0495 - 1.422 0.173 - 180.5 1 2 0 0 8 0 0 0 1.08E+07 1.58E+07 - - - 1.3806 0.999 221125_WJC_METTL3_EV_vs_WT_F01.16971.16971.2 0.00157 16-Sep K.YFNYLYTYK.M "sp|Q93063|EXT2_HUMAN,tr|A0A804HKG2|A0A804HKG2_HUMAN,tr|A0A804HL74|A0A804HL74_HUMAN,tr|A0A804HHX4|A0A804HHX4_HUMAN" 4 1273.6019 0.46 4937 16971 2 1273.602899 637.8082 Exostosin-2 OS=Homo sapiens OX=9606 GN=EXT2 PE=1 SV=1 8.38 3382.7 - 175651 - - - 0.764 - 1.348 0.356 - 198.7 1 2 0 0.001 9 0 0 0 1.36E+06 2.94E+06 - - - 2.534 0.9999 221125_WJC_METTL3_EV_vs_WT_F01.16973.16973.2 0.00188 18-Nov K.VVDLLAPYAK.G "sp|P06576|ATPB_HUMAN,tr|F8W079|F8W079_HUMAN,tr|H0YH81|H0YH81_HUMAN" 3 1087.6277 1.89 4938 16973 2 1087.628854 544.8211 "ATP synthase subunit beta, mitochondrial OS=Homo sapiens OX=9606 GN=ATP5F1B PE=1 SV=3" 5.81 3383 - 7.84E+06 - - - 1.0178 - 2.346 0.485 - 459.7 1 2 0 0.0011 10 0 0 0 1.41E+09 7.50E+08 - - - 5.003 0.9984 221125_WJC_METTL3_EV_vs_WT_F01.16978.16978.2 0.13 14-Aug R.GIFEPFGK.L "sp|Q86U06|RBM23_HUMAN,tr|H0YJJ3|H0YJJ3_HUMAN,tr|G3XAP0|G3XAP0_HUMAN,tr|G3V5Z6|G3V5Z6_HUMAN" 4 893.4647 0.64 4942 16978 2 893.465037 447.7396 Probable RNA-binding protein 23 OS=Homo sapiens OX=9606 GN=RBM23 PE=1 SV=1 6 3383.5 - 837002 - - - 0.3727 - 1.484 0.242 - 202.5 1 2 0 0.0003 8 0 0 0 9.26E+07 1.44E+08 - - - 2.0188 0.979 221125_WJC_METTL3_EV_vs_WT_F01.16979.16979.2 0.019 16-Dec R.PLVALLDGR[166.11].D "sp|P56545|CTBP2_HUMAN,sp|Q13363|CTBP1_HUMAN,tr|E7ESU7|E7ESU7_HUMAN,tr|E7EUB3|E7EUB3_HUMAN,tr|D6RAX2|D6RAX2_HUMAN,tr|E7EPF8|E7EPF8_HUMAN,tr|E9PGB1|E9PGB1_HUMAN" 7 962.5788 1.05 4943 16979 2 962.579675 482.2967 C-terminal-binding protein 2 OS=Homo sapiens OX=9606 GN=CTBP2 PE=1 SV=1 6.27 3383.6 - 643037 - - - 0.8716 - 2.286 0.298 - 480.1 1 1 0 0.0008 9 0 0 0 3.15E+07 3.00E+07 - - - 3.6338 0.9954 221125_WJC_METTL3_EV_vs_WT_F01.16986.16986.2 1.17 16-Jul K.IILEPMDLK.L "sp|Q86U86|PB1_HUMAN,tr|H0Y5B5|H0Y5B5_HUMAN,tr|E7EVG2|E7EVG2_HUMAN" 3 1070.6046 1.62 4949 16986 2 1070.606195 536.3096 Protein polybromo-1 OS=Homo sapiens OX=9606 GN=PBRM1 PE=1 SV=1 4.37 3384.4 - 1.97E+06 - - - 1.5188 - 1.351 0.224 - 108.1 1 2 0 0.0016 9 0 0 0 7.34E+07 4.53E+07 - - - 1.5653 0.9999 221125_WJC_METTL3_EV_vs_WT_F01.16988.16988.2 3.63E-05 14/20 R.MGPGIGAILER[166.11].S "sp|Q9P2K5|MYEF2_HUMAN,tr|A0A0A0MR39|A0A0A0MR39_HUMAN,tr|A0A0C4DGV1|A0A0C4DGV1_HUMAN,tr|A0A087WUT0|A0A087WUT0_HUMAN,tr|H0YKS1|H0YKS1_HUMAN,tr|H0YN19|H0YN19_HUMAN,tr|A0A0A0MQW0|A0A0A0MQW0_HUMAN" 7 1122.6095 1.2 4950 16988 2 1122.610354 562.312 Myelin expression factor 2 OS=Homo sapiens OX=9606 GN=MYEF2 PE=1 SV=3 5.75 3384.7 - 2.35E+06 - - - 0.775 - 2.361 0.495 - 692.1 1 2 0 0.0009 11 0 0 0 1.65E+08 1.37E+08 - - - 5.0208 0.8954 221125_WJC_METTL3_EV_vs_WT_F01.16989.16989.2 0.0287 22-Jul K.LSPVVGAVYGPE.L "sp|O43251|RFOX2_HUMAN,tr|B0QYV1|B0QYV1_HUMAN,tr|B0QYY4|B0QYY4_HUMAN,tr|S4R469|S4R469_HUMAN,tr|A0A0G2JRD1|A0A0G2JRD1_HUMAN,tr|A0A0G2JRA5|A0A0G2JRA5_HUMAN,tr|S4R3K7|S4R3K7_HUMAN" 7 1186.6234 - 4951 16989 2 1186.623775 594.319 RNA binding protein fox-1 homolog 2 OS=Homo sapiens OX=9606 GN=RBFOX2 PE=1 SV=3 4.6 3384.7 - 1.70E+06 - - - 0.3245 - 1.148 0.331 - 115.7 1 1 0 0.0004 12 0 0 0 - - - - - 1.8488 0.9999 221125_WJC_METTL3_EV_vs_WT_F01.16990.16990.2 4.18E-05 20-Dec R.MGPGIGAILER.S "sp|Q9P2K5|MYEF2_HUMAN,tr|A0A0A0MR39|A0A0A0MR39_HUMAN,tr|A0A0C4DGV1|A0A0C4DGV1_HUMAN,tr|A0A087WUT0|A0A087WUT0_HUMAN,tr|H0YKS1|H0YKS1_HUMAN,tr|H0YN19|H0YN19_HUMAN,tr|A0A0A0MQW0|A0A0A0MQW0_HUMAN" 7 1112.6012 1.19 4952 16990 2 1112.601186 557.3079 Myelin expression factor 2 OS=Homo sapiens OX=9606 GN=MYEF2 PE=1 SV=3 5.75 3384.8 - 2.17E+06 - - - -0.0252 - 2.301 0.502 - 467.4 1 2 0 0 11 0 0 0 1.63E+08 1.37E+08 - - - 5.0032 0.9984 221125_WJC_METTL3_EV_vs_WT_F01.16991.16991.2 0.173 14-Jul K.FYFEELGK.Y sp|Q10471|GALT2_HUMAN 1 1031.4964 1.08 4953 16991 2 1031.494797 516.7555 Polypeptide N-acetylgalactosaminyltransferase 2 OS=Homo sapiens OX=9606 GN=GALNT2 PE=1 SV=1 4.53 3384.8 - 1.64E+06 - - - -1.5521 - 1.401 0.315 - 136.2 1 2 0 -0.0016 8 0 0 0 5.20E+07 4.81E+07 - - - 2.384 0.9998 221125_WJC_METTL3_EV_vs_WT_F01.16992.16992.2 0.000175 18-Sep R.VVLPIEAPIR[166.11].M sp|P00403|COX2_HUMAN 1 1115.6942 1.34 4954 16992 2 1115.694265 558.8544 Cytochrome c oxidase subunit 2 OS=Homo sapiens OX=9606 GN=MT-CO2 PE=1 SV=1 5.97 3384.9 - 1.23E+06 - - - 0.0583 - 1.897 0.422 - 335.5 1 2 0 0.0001 10 0 0 0 3.25E+08 2.42E+08 - - - 3.9451 0.9918 221125_WJC_METTL3_EV_vs_WT_F01.16995.16995.2 0.165 12-Aug K.IVVLFYK[136.11].A "sp|Q9Y6E2|BZW2_HUMAN,sp|Q7L1Q6|BZW1_HUMAN,tr|B5MCH7|B5MCH7_HUMAN,tr|E9PFD4|E9PFD4_HUMAN,tr|E7ETZ4|E7ETZ4_HUMAN,tr|B5MCE7|B5MCE7_HUMAN" 6 888.5564 0.7 4957 16995 2 888.557178 445.2855 Basic leucine zipper and W2 domain-containing protein 2 OS=Homo sapiens OX=9606 GN=BZW2 PE=1 SV=1 8.59 3385.3 - 611092 - - - 0.8463 - 1.35 0.123 - 201 1 2 0 0.0008 7 0 0 0 1.12E+07 1.61E+07 - - - 0.9001 0.9996 221125_WJC_METTL3_EV_vs_WT_F01.17003.17003.2 0.0209 18-Aug R.VVLPIEAPIR.M sp|P00403|COX2_HUMAN 1 1105.6859 1.34 4963 17003 2 1105.685973 553.8502 Cytochrome c oxidase subunit 2 OS=Homo sapiens OX=9606 GN=MT-CO2 PE=1 SV=1 5.97 3386.3 - 4.56E+06 - - - 0.0389 - 1.728 0.375 - 259.1 1 2 0 0 10 0 0 0 3.25E+08 2.42E+08 - - - 3.3375 0.9996 221125_WJC_METTL3_EV_vs_WT_F01.17004.17004.2 0.00306 16-Dec R.LPLALNPLK.S "sp|Q0P6D6|CCD15_HUMAN,tr|E9PKB1|E9PKB1_HUMAN" 2 977.6274 2.01 4964 17004 2 977.629015 489.821 Coiled-coil domain-containing protein 15 OS=Homo sapiens OX=9606 GN=CCDC15 PE=2 SV=2 8.75 3386.4 - 852034 - - - 1.7 - 2.07 0.4 - 416.9 1 2 0 0.0017 9 0 0 0 1.01E+07 5.00E+06 - - - 4.0997 0.9996 221125_WJC_METTL3_EV_vs_WT_F01.17006.17006.2 0.000249 20-Oct R.FLPEFAGTQLK.L sp|Q9UBZ4|APEX2_HUMAN 1 1249.6707 0.95 4966 17006 2 1249.67158 625.8426 DNA-(apurinic or apyrimidinic site) endonuclease 2 OS=Homo sapiens OX=9606 GN=APEX2 PE=1 SV=1 6 3386.6 - 916329 - - - 0.725 - 1.629 0.412 - 323.8 1 2 0 0.0009 11 0 0 0 3.13E+07 3.30E+07 - - - 3.4038 0.9961 221125_WJC_METTL3_EV_vs_WT_F01.17008.17008.2 0.00682 16-Jul K.ITPLMSAFR[166.11].K "sp|Q8IWZ3|ANKH1_HUMAN,tr|E9PDP5|E9PDP5_HUMAN,tr|H3BLS9|H3BLS9_HUMAN,tr|H0Y4P6|H0Y4P6_HUMAN,tr|H7C2F5|H7C2F5_HUMAN" 5 1044.5666 3.25 4968 17008 2 1044.564513 523.2906 Ankyrin repeat and KH domain-containing protein 1 OS=Homo sapiens OX=9606 GN=ANKHD1 PE=1 SV=1 9.75 3386.8 - 677486 - - - -1.9568 - 1.383 0.252 - 116 1 2 0 -0.002 9 0 0 0 1.30E+09 4.00E+08 - - - 1.8397 0.9991 221125_WJC_METTL3_EV_vs_WT_F01.17010.17010.2 0.00324 18-Jun K.LEMYVLNPVK.S "sp|P46821|MAP1B_HUMAN,tr|D6RA32|D6RA32_HUMAN,tr|D6RA40|D6RA40_HUMAN" 3 1204.6526 0.88 4970 17010 2 1204.653947 603.3336 Microtubule-associated protein 1B OS=Homo sapiens OX=9606 GN=MAP1B PE=1 SV=2 6 3387.1 - 305117 - - - 1.1339 - 1.563 0.362 - 106.8 3 2 0 0.0014 10 0 0 0 5.57E+06 6.33E+06 - - - 2.7478 0.9988 221125_WJC_METTL3_EV_vs_WT_F01.17015.17015.2 0.0311 14-Jul K.DIVYIGLR.D "sp|P05089|ARGI1_HUMAN,tr|A0A5F9ZGN6|A0A5F9ZGN6_HUMAN" 2 947.544 999 4973 17015 2 947.544683 474.7793 Arginase-1 OS=Homo sapiens OX=9606 GN=ARG1 PE=1 SV=2 5.84 3387.8 - 7.05E+06 - - - 0.7029 - 1.433 0.301 - 208.7 1 2 0 0.0007 8 0 0 0 7.28E+07 0.00E+00 - - - 2.349 0.8113 221125_WJC_METTL3_EV_vs_WT_F01.17017.17017.2 0.0489 22-Jun R.VINEPTAAALAY.G "sp|P38646|GRP75_HUMAN,tr|H0Y8K0|H0Y8K0_HUMAN,tr|A0A7I2V2S7|A0A7I2V2S7_HUMAN,tr|A0A7I2V2G2|A0A7I2V2G2_HUMAN,tr|A0A7I2V3F7|A0A7I2V3F7_HUMAN,tr|A0A7I2YQB2|A0A7I2YQB2_HUMAN,tr|D6RCD7|D6RCD7_HUMAN" 7 1231.6449 - 4975 17017 2 1231.64272 616.8297 "Stress-70 protein, mitochondrial OS=Homo sapiens OX=9606 GN=HSPA9 PE=1 SV=2" 4 3388 - 1.69E+06 - - - -1.7318 - 1.262 0.282 - 96.1 1 1 0 -0.0021 12 0 0 0 - - - - - 1.7354 0.9962 221125_WJC_METTL3_EV_vs_WT_F01.17018.17018.2 0.00659 20-Sep R.VGMIPVPYVEK[136.11].L sp|P46109|CRKL_HUMAN 1 1238.6824 0.39 4976 17018 2 1238.685205 620.3485 Crk-like protein OS=Homo sapiens OX=9606 GN=CRKL PE=1 SV=1 5.97 3388 - 1.05E+06 - - - 2.2395 - 1.555 0.251 - 215.7 1 2 0 0.0028 11 0 0 0 4.88E+06 1.26E+07 - - - 2.0883 0.9606 221125_WJC_METTL3_EV_vs_WT_F01.17019.17019.2 0.0168 20-Oct R.FLPEFAGTQLK[136.11].L sp|Q9UBZ4|APEX2_HUMAN 1 1257.6849 1.03 4977 17019 2 1258.688042 629.8497 DNA-(apurinic or apyrimidinic site) endonuclease 2 OS=Homo sapiens OX=9606 GN=APEX2 PE=1 SV=1 6 3388.1 - 973059 - - - 797.6306 - 1.666 0.306 - 300 1 2 0 1.0032 11 0 0 0 3.21E+07 3.12E+07 - - - 2.3669 0.9998 221125_WJC_METTL3_EV_vs_WT_F01.17021.17021.2 0.000414 13/22 R.LGASLAFNNIYR[166.11].E sp|P78527|PRKDC_HUMAN 1 1347.7175 0.59 4979 17021 2 1347.716045 674.866 DNA-dependent protein kinase catalytic subunit OS=Homo sapiens OX=9606 GN=PRKDC PE=1 SV=3 8.75 3388.4 - 633782 - - - -1.0462 - 2.581 0.435 - 675.8 1 2 0 -0.0014 12 0 0 0 5.43E+06 9.21E+06 - - - 4.7483 0.9989 221125_WJC_METTL3_EV_vs_WT_F01.17024.17024.2 0.00771 18-Aug R.EGDLLFTVAK[136.11].D "sp|Q13347|EIF3I_HUMAN,tr|A0A7I2V613|A0A7I2V613_HUMAN,tr|A0A7I2V3N2|A0A7I2V3N2_HUMAN,tr|A0A7I2YQU2|A0A7I2YQU2_HUMAN,tr|A0A7I2YQX4|A0A7I2YQX4_HUMAN,tr|A0A7I2YQI6|A0A7I2YQI6_HUMAN,tr|A0A7I2YQF8|A0A7I2YQF8_HUMAN,tr|Q5TFK1|Q5TFK1_HUMAN,tr|A0A7I2V3U3|A0A7I2V3U3_HUMAN,tr|A0A7I2V607|A0A7I2V607_HUMAN,tr|A0A7I2V640|A0A7I2V640_HUMAN,tr|A0A7P0MRT9|A0A7P0MRT9_HUMAN,tr|A0A7I2V3T4|A0A7I2V3T4_HUMAN,tr|A0A7I2V3K6|A0A7I2V3K6_HUMAN,tr|A0A7I2V4S8|A0A7I2V4S8_HUMAN,tr|A0A7I2V5V8|A0A7I2V5V8_HUMAN,tr|A0A7I2V391|A0A7I2V391_HUMAN,tr|A0A7I2V5E4|A0A7I2V5E4_HUMAN,tr|A0A7I2YQN1|A0A7I2YQN1_HUMAN,tr|A0A7I2V2M3|A0A7I2V2M3_HUMAN,tr|A0A7I2V4C2|A0A7I2V4C2_HUMAN,tr|A0A7I2YQP9|A0A7I2YQP9_HUMAN,tr|A0A7I2YQI2|A0A7I2YQI2_HUMAN,tr|A0A7I2V685|A0A7I2V685_HUMAN" 24 1099.6005 1.37 4982 17024 2 1099.600904 550.8075 Eukaryotic translation initiation factor 3 subunit I OS=Homo sapiens OX=9606 GN=EIF3I PE=1 SV=1 4.37 3388.8 - 344713 - - - 0.3892 - 1.46 0.303 - 169.4 1 2 0 0.0004 10 0 0 0 2.27E+07 1.66E+07 - - - 2.3352 0.8955 221125_WJC_METTL3_EV_vs_WT_F01.17027.17027.2 3.58 12-May R.ALSDLFK.H sp|Q9NU22|MDN1_HUMAN 1 792.4382 0.65 4985 17027 2 792.437958 397.2264 Midasin OS=Homo sapiens OX=9606 GN=MDN1 PE=1 SV=2 5.88 3389.1 - 268054 - - - -0.2486 - 0.882 0.058 - 66.9 1 2 0 -0.0002 7 0 0 0 3.02E+06 4.65E+06 - - - -0.9285 0.9999 221125_WJC_METTL3_EV_vs_WT_F01.17032.17032.2 4.31E-05 18-Nov K.WTETEIEMLR.A "sp|Q8IXM2|BAP18_HUMAN,tr|H0YIS7|H0YIS7_HUMAN,tr|F8W038|F8W038_HUMAN,tr|F8W1H0|F8W1H0_HUMAN" 4 1306.6227 0.31 4988 17032 2 1306.623543 654.3186 Chromatin complexes subunit BAP18 OS=Homo sapiens OX=9606 GN=BAP18 PE=1 SV=1 4.25 3389.7 - 979014 - - - 0.6161 - 2.259 0.484 - 517.3 1 2 0 0.0008 10 0 0 0 1.12E+07 3.60E+07 - - - 4.8903 0.9997 221125_WJC_METTL3_EV_vs_WT_F01.17033.17033.2 0.000676 14-Aug R.LNVWDLSK.L "sp|Q09028|RBBP4_HUMAN,sp|Q16576|RBBP7_HUMAN,tr|H0YCT5|H0YCT5_HUMAN,tr|H0YDK2|H0YDK2_HUMAN,tr|Q5JP02|Q5JP02_HUMAN,tr|H0YEU5|H0YEU5_HUMAN,tr|Q5JNZ6|Q5JNZ6_HUMAN,tr|H0YF10|H0YF10_HUMAN,tr|E9PC52|E9PC52_HUMAN" 9 973.5233 3.47 4989 17033 2 973.524068 487.7689 Histone-binding protein RBBP4 OS=Homo sapiens OX=9606 GN=RBBP4 PE=1 SV=3 5.84 3389.8 - 803174 - - - 0.8074 - 1.826 0.407 - 191.9 1 2 0 0.0008 8 0 0 0 1.53E+07 4.41E+06 - - - 3.8628 0.9999 221125_WJC_METTL3_EV_vs_WT_F01.17034.17034.2 2.25E-05 18-Nov R.QIDQFLVVAR.A "sp|Q9BTC8|MTA3_HUMAN,sp|O94776|MTA2_HUMAN,sp|Q13330|MTA1_HUMAN,tr|E9PCS8|E9PCS8_HUMAN,tr|H0Y4T7|H0Y4T7_HUMAN,tr|E7EQY4|E7EQY4_HUMAN,tr|E7EV10|E7EV10_HUMAN,tr|F6RRE2|F6RRE2_HUMAN,tr|E7ESY4|E7ESY4_HUMAN" 9 1187.6663 2.07 4990 17034 2 1187.667538 594.8404 Metastasis-associated protein MTA3 OS=Homo sapiens OX=9606 GN=MTA3 PE=1 SV=2 5.84 3389.9 - 848215 - - - 1.0777 - 2.193 0.549 - 672 1 2 0 0.0013 10 0 0 0 4.92E+07 2.38E+07 - - - 5.2874 0.9037 221125_WJC_METTL3_EV_vs_WT_F01.17035.17035.2 0.0854 14-Jul V.VGDIAQVK[136.11].Y "sp|Q01814|AT2B2_HUMAN,sp|P20020|AT2B1_HUMAN,sp|Q16720|AT2B3_HUMAN,sp|P23634|AT2B4_HUMAN,tr|A0A804HKZ0|A0A804HKZ0_HUMAN,tr|A0A2U3TZI3|A0A2U3TZI3_HUMAN,tr|A0A2U3U055|A0A2U3U055_HUMAN" 7 836.4847 2.66 4991 17035 2 836.484719 419.2496 Plasma membrane calcium-transporting ATPase 2 OS=Homo sapiens OX=9606 GN=ATP2B2 PE=1 SV=2 5.81 3390 - 639108 - - - 0.0012 - 1.32 0.272 - 117.1 1 1 0 0 8 0 0 0 2.04E+07 7.66E+06 - - - 1.8873 0.9998 221125_WJC_METTL3_EV_vs_WT_F01.17037.17037.2 0.000217 18-Nov K.AVVMLEYVER[166.11].A "sp|Q13617|CUL2_HUMAN,tr|Q5T2B5|Q5T2B5_HUMAN,tr|Q5T2B7|Q5T2B7_HUMAN,tr|A0A0A0MTN0|A0A0A0MTN0_HUMAN" 4 1217.6354 0.37 4993 17037 2 1217.637322 609.825 Cullin-2 OS=Homo sapiens OX=9606 GN=CUL2 PE=1 SV=2 4.53 3390.3 - 458846 - - - 1.6072 - 2.37 0.505 - 679.9 1 2 0 0.002 10 0 0 0 3.03E+06 8.12E+06 - - - 5.1789 0.9988 221125_WJC_METTL3_EV_vs_WT_F01.17042.17042.2 0.034 16-Aug K.LAFNSLLEK[136.11].A "sp|O75400|PR40A_HUMAN,tr|A0A7N4I394|A0A7N4I394_HUMAN" 2 1041.595 1.35 4996 17042 2 1041.597195 521.8048 Pre-mRNA-processing factor 40 homolog A OS=Homo sapiens OX=9606 GN=PRPF40A PE=1 SV=2 6 3390.8 - 3.24E+06 - - - 2.1102 - 1.649 0.352 - 153.7 1 2 0 0.0022 9 0 0 0 6.74E+07 4.98E+07 - - - 3.0872 0.9994 221125_WJC_METTL3_EV_vs_WT_F01.17043.17043.2 0.00921 16-Oct K.SALLALGLK.C sp|Q12874|SF3A3_HUMAN 1 884.5695 4.05 4997 17043 2 884.570664 443.292 Splicing factor 3A subunit 3 OS=Homo sapiens OX=9606 GN=SF3A3 PE=1 SV=1 8.47 3390.9 - 1.59E+06 - - - 1.3114 - 2.092 0.294 - 297.8 1 2 0 0.0012 9 0 0 0 7.85E+08 1.94E+08 - - - 3.3475 0.994 221125_WJC_METTL3_EV_vs_WT_F01.17044.17044.2 0.16 18-Jun R.EGDLLFTVAK.D "sp|Q13347|EIF3I_HUMAN,tr|A0A7I2V613|A0A7I2V613_HUMAN,tr|A0A7I2V3N2|A0A7I2V3N2_HUMAN,tr|A0A7I2YQU2|A0A7I2YQU2_HUMAN,tr|A0A7I2YQX4|A0A7I2YQX4_HUMAN,tr|A0A7I2YQI6|A0A7I2YQI6_HUMAN,tr|A0A7I2YQF8|A0A7I2YQF8_HUMAN,tr|Q5TFK1|Q5TFK1_HUMAN,tr|A0A7I2V3U3|A0A7I2V3U3_HUMAN,tr|A0A7I2V607|A0A7I2V607_HUMAN,tr|A0A7I2V640|A0A7I2V640_HUMAN,tr|A0A7P0MRT9|A0A7P0MRT9_HUMAN,tr|A0A7I2V3T4|A0A7I2V3T4_HUMAN,tr|A0A7I2V3K6|A0A7I2V3K6_HUMAN,tr|A0A7I2V4S8|A0A7I2V4S8_HUMAN,tr|A0A7I2V5V8|A0A7I2V5V8_HUMAN,tr|A0A7I2V391|A0A7I2V391_HUMAN,tr|A0A7I2V5E4|A0A7I2V5E4_HUMAN,tr|A0A7I2YQN1|A0A7I2YQN1_HUMAN,tr|A0A7I2V2M3|A0A7I2V2M3_HUMAN,tr|A0A7I2V4C2|A0A7I2V4C2_HUMAN,tr|A0A7I2YQP9|A0A7I2YQP9_HUMAN,tr|A0A7I2YQI2|A0A7I2YQI2_HUMAN,tr|A0A7I2V685|A0A7I2V685_HUMAN" 24 1091.5863 1.37 4998 17044 2 1091.589647 546.8004 Eukaryotic translation initiation factor 3 subunit I OS=Homo sapiens OX=9606 GN=EIF3I PE=1 SV=1 4.37 3391 - 1.09E+06 - - - 3.0882 - 1.462 0.283 - 97.6 1 2 0 0.0034 10 0 0 0 2.27E+07 1.66E+07 - - - 2.1903 0.9997 221125_WJC_METTL3_EV_vs_WT_F01.17045.17045.2 0.000194 14-Sep K.GFGFGLVK.L "sp|P45880|VDAC2_HUMAN,tr|A2A3S1|A2A3S1_HUMAN,tr|Q5JSD1|Q5JSD1_HUMAN,tr|Q5JSD2|Q5JSD2_HUMAN,tr|A0A0A0MR02|A0A0A0MR02_HUMAN" 5 823.4592 1.26 4999 17045 2 823.459552 412.7369 Voltage-dependent anion-selective channel protein 2 OS=Homo sapiens OX=9606 GN=VDAC2 PE=1 SV=2 8.75 3391.1 - 941847 - - - 0.3971 - 1.553 0.429 - 254.1 1 2 0 0.0003 8 0 0 0 6.41E+08 5.09E+08 - - - 3.5371 0.9997 221125_WJC_METTL3_EV_vs_WT_F01.17046.17046.2 0.000477 14-Aug K.GFGFGLVK[136.11].L "sp|P45880|VDAC2_HUMAN,tr|A2A3S1|A2A3S1_HUMAN,tr|Q5JSD1|Q5JSD1_HUMAN,tr|Q5JSD2|Q5JSD2_HUMAN,tr|A0A0A0MR02|A0A0A0MR02_HUMAN" 5 831.4734 1.25 5000 17046 2 831.474286 416.744 Voltage-dependent anion-selective channel protein 2 OS=Homo sapiens OX=9606 GN=VDAC2 PE=1 SV=2 8.75 3391.2 - 900051 - - - 1.0355 - 1.463 0.488 - 205.3 1 2 0 0.0009 8 0 0 0 6.38E+08 5.08E+08 - - - 3.7926 0.9857 221125_WJC_METTL3_EV_vs_WT_F01.17047.17047.2 0.000487 20-Sep N.VPVGIDYVIPK[136.11].T "sp|P43243|MATR3_HUMAN,tr|B3KM87|B3KM87_HUMAN,tr|A8MXP9|A8MXP9_HUMAN,tr|A0A0R4J2E8|A0A0R4J2E8_HUMAN" 4 1206.7104 3.43 5001 17047 2 1206.710315 604.3625 Matrin-3 OS=Homo sapiens OX=9606 GN=MATR3 PE=1 SV=2 5.81 3391.3 - 547727 - - - -0.0381 - 1.717 0.451 - 147.3 1 1 0 0 11 0 0 0 6.03E+07 1.76E+07 - - - 3.8345 0.9926 221125_WJC_METTL3_EV_vs_WT_F01.17054.17054.2 0.0451 12-Jul K.SYFLIVR[166.11].K sp|O00429|DNM1L_HUMAN 1 906.5203 1.07 5007 17054 2 906.522558 454.2674 Dynamin-1-like protein OS=Homo sapiens OX=9606 GN=DNM1L PE=1 SV=2 8.46 3392.2 - 328238 - - - 2.5361 - 1.287 0.252 - 150 1 2 0 0.0023 7 0 0 0 1.36E+07 1.27E+07 - - - 1.701 0.999 221125_WJC_METTL3_EV_vs_WT_F01.17055.17055.2 0.0429 16-Aug K.IAFAITAIK[136.11].G "sp|P62269|RS18_HUMAN,tr|A0A0G2JQH2|A0A0G2JQH2_HUMAN,tr|Q5GGW2|Q5GGW2_HUMAN" 3 954.5994 0.99 5008 17055 2 954.600633 478.307 40S ribosomal protein S18 OS=Homo sapiens OX=9606 GN=RPS18 PE=1 SV=3 8.75 3392.2 - 6.05E+06 - - - 1.3398 - 1.791 0.282 - 127.1 1 2 0 0.0013 9 0 0 0 1.76E+09 1.78E+09 - - - 2.8094 0.9496 221125_WJC_METTL3_EV_vs_WT_F01.17059.17059.2 0.0143 22-Jun R.LNVGGTYFLTTR.Q "sp|Q9NXV2|KCTD5_HUMAN,tr|H3BSS5|H3BSS5_HUMAN" 2 1340.7089 1.57 5012 17059 2 1340.70133 671.3617 BTB\POZ domain-containing protein KCTD5 OS=Homo sapiens OX=9606 GN=KCTD5 PE=1 SV=1 8.75 3392.7 - 234336 - - - -5.6097 - 1.487 0.28 - 53 4 2 0 -0.0075 12 0 0 0 1.77E+06 1.13E+06 - - - 1.8817 0.9998 221125_WJC_METTL3_EV_vs_WT_F01.17062.17062.2 0.00703 16-Nov K.IAFAITAIK.G "sp|P62269|RS18_HUMAN,tr|A0A0G2JQH2|A0A0G2JQH2_HUMAN,tr|Q5GGW2|Q5GGW2_HUMAN" 3 946.5852 0.99 5013 17062 2 946.585443 474.2999 40S ribosomal protein S18 OS=Homo sapiens OX=9606 GN=RPS18 PE=1 SV=3 8.75 3393.1 - 9.54E+06 - - - 0.3053 - 2.068 0.379 - 303.9 1 2 0 0.0003 9 0 0 0 1.76E+09 1.78E+09 - - - 3.9422 0.9715 221125_WJC_METTL3_EV_vs_WT_F01.17064.17064.2 0.36 14-Aug K.TILSLMTR.E sp|P53396|ACLY_HUMAN 1 933.5317 1.07 5015 17064 2 933.533249 467.7731 ATP-citrate synthase OS=Homo sapiens OX=9606 GN=ACLY PE=1 SV=3 9.41 3393.2 - 1.56E+06 - - - 1.6186 - 1.338 0.054 - 197.4 1 2 0 0.0015 8 0 0 0 5.56E+07 5.22E+07 - - - 0.3175 0.9577 221125_WJC_METTL3_EV_vs_WT_F01.17065.17065.2 5.32 14-Jun R.LEMYNILK.A "sp|P26639|SYTC_HUMAN,tr|D6RCA5|D6RCA5_HUMAN,tr|D6R9F8|D6R9F8_HUMAN,tr|D6RDJ6|D6RDJ6_HUMAN" 4 1022.5471 0.47 5016 17065 2 1022.546768 512.2808 "Threonine--tRNA ligase 1, cytoplasmic OS=Homo sapiens OX=9606 GN=TARS1 PE=1 SV=3" 6 3393.4 - 870452 - - - -0.2797 - 1.09 0.05 - 67.7 1 2 0 -0.0003 8 0 0 0 6.53E+06 1.38E+07 - - - -0.3299 0.9995 221125_WJC_METTL3_EV_vs_WT_F01.17066.17066.2 0.00409 28-Sep R.IITGPAPVLPPAALR.T "sp|Q96PU8|QKI_HUMAN,tr|H0YG47|H0YG47_HUMAN,tr|H0YGD6|H0YGD6_HUMAN" 3 1484.9079 4.15 5017 17066 2 1484.907356 743.4612 Protein quaking OS=Homo sapiens OX=9606 GN=QKI PE=1 SV=1 9.75 3393.5 - 337190 - - - -0.3563 - 1.606 0.37 - 167.6 1 2 0 -0.0005 15 0 0 0 5.65E+08 1.36E+08 - - - 2.9384 0.9999 221125_WJC_METTL3_EV_vs_WT_F01.17067.17067.2 2.56E-06 22-Sep R.LLLENYEEYAAR[166.11].A "sp|Q16763|UBE2S_HUMAN,tr|K7EPJ1|K7EPJ1_HUMAN" 2 1492.7437 0.79 5018 17067 2 1492.745045 747.3791 Ubiquitin-conjugating enzyme E2 S OS=Homo sapiens OX=9606 GN=UBE2S PE=1 SV=2 4.25 3393.6 - 220409 - - - 0.8816 - 2.157 0.565 - 248.2 1 2 0 0.0013 12 0 0 0 1.81E+06 2.28E+06 - - - 5.2363 0.9977 221125_WJC_METTL3_EV_vs_WT_F01.17073.17073.2 0.0527 16-Sep K.SALLALGLK[136.11].C sp|Q12874|SF3A3_HUMAN 1 892.5837 4.06 5022 17073 2 892.582442 447.2991 Splicing factor 3A subunit 3 OS=Homo sapiens OX=9606 GN=SF3A3 PE=1 SV=1 8.47 3394.2 - 6.17E+06 - - - -1.4139 - 1.722 0.188 - 277.9 1 2 0 -0.0013 9 0 0 0 7.83E+08 1.93E+08 - - - 2.0015 0.9995 221125_WJC_METTL3_EV_vs_WT_F01.17076.17076.2 0.00876 16-Sep K.ALQFLEEVK[136.11].V sp|P40227|TCPZ_HUMAN 1 1083.6056 0.34 5025 17076 2 1083.603929 542.8101 T-complex protein 1 subunit zeta OS=Homo sapiens OX=9606 GN=CCT6A PE=1 SV=3 4.53 3394.4 - 1.94E+06 - - - -1.5061 - 1.939 0.339 - 279.2 1 2 0 -0.0016 9 0 0 0 5.41E+07 1.58E+08 - - - 3.46 0.8185 221125_WJC_METTL3_EV_vs_WT_F01.17078.17078.2 0.261 16-Jul K.ALQFLEEVK.V sp|P40227|TCPZ_HUMAN 1 1075.5914 0.33 5027 17078 2 1075.596506 538.803 T-complex protein 1 subunit zeta OS=Homo sapiens OX=9606 GN=CCT6A PE=1 SV=3 4.53 3394.6 - 1.16E+06 - - - 4.7834 - 1.189 0.123 - 103.6 1 2 0 0.0051 9 0 0 0 5.17E+07 1.57E+08 - - - 0.4487 0.9986 221125_WJC_METTL3_EV_vs_WT_F01.17079.17079.2 0.00748 16-Sep K.IFTQLEEFR[166.11].A sp|O60306|AQR_HUMAN 1 1191.6163 0.99 5028 17079 2 1191.612485 596.8154 RNA helicase aquarius OS=Homo sapiens OX=9606 GN=AQR PE=1 SV=4 4.53 3394.7 - 942273 - - - -3.2385 - 1.935 0.373 - 293.3 1 2 0 -0.0039 9 0 0 0 9.63E+06 9.74E+06 - - - 3.7045 0.9997 221125_WJC_METTL3_EV_vs_WT_F01.17082.17082.2 0.00773 18-Oct K.IYVISLAEPR.L "sp|P14868|SYDC_HUMAN,tr|C9JQM9|C9JQM9_HUMAN,tr|C9J7S3|C9J7S3_HUMAN,tr|C9JLC1|C9JLC1_HUMAN" 4 1159.6601 1.04 5030 17082 2 1159.658086 580.8373 "Aspartate--tRNA ligase, cytoplasmic OS=Homo sapiens OX=9606 GN=DARS1 PE=1 SV=2" 6 3395.1 - 2.44E+06 - - - -1.7453 - 2.245 0.434 - 493.6 1 2 0 -0.002 10 0 0 0 6.29E+07 6.07E+07 - - - 4.5032 0.9999 221125_WJC_METTL3_EV_vs_WT_F01.17083.17083.2 0.000823 18-Dec K.IYVISLAEPR[166.11].L "sp|P14868|SYDC_HUMAN,tr|C9JQM9|C9JQM9_HUMAN,tr|C9J7S3|C9J7S3_HUMAN,tr|C9JLC1|C9JLC1_HUMAN" 4 1169.6684 1.03 5031 17083 2 1169.667725 585.8415 "Aspartate--tRNA ligase, cytoplasmic OS=Homo sapiens OX=9606 GN=DARS1 PE=1 SV=2" 6 3395.2 - 1.84E+06 - - - -0.56 - 2.476 0.447 - 554.9 1 2 0 -0.0007 10 0 0 0 6.29E+07 6.08E+07 - - - 4.8731 0.9998 221125_WJC_METTL3_EV_vs_WT_F01.17084.17084.2 0.00773 16-Sep R.YLDVSILGK.F sp|Q86U44|MTA70_HUMAN 1 1006.5699 0.03 5032 17084 2 1006.569587 504.2922 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 5.83 3395.2 - 2.84E+07 - - - -0.309 - 1.715 0.448 - 175.9 1 2 0 -0.0003 9 0 0 0 1.79E+10 6.33E+11 - - - 3.9104 0.9995 221125_WJC_METTL3_EV_vs_WT_F01.17087.17087.2 2.90E-06 13/20 K.VADIGLAAWGR.K sp|P23526|SAHH_HUMAN 1 1127.6087 0.49 5035 17087 2 1127.605379 564.8116 Adenosylhomocysteinase OS=Homo sapiens OX=9606 GN=AHCY PE=1 SV=4 5.81 3395.5 - 1.23E+06 - - - -2.9833 - 2.679 0.437 - 685.4 1 2 0 -0.0034 11 0 0 0 1.92E+07 3.91E+07 - - - 4.9335 0.9939 221125_WJC_METTL3_EV_vs_WT_F01.17090.17090.2 0.00241 18-Jul R.LGLPGEVFGR.S sp|O95409|ZIC2_HUMAN 1 1043.5764 3.08 5036 17090 2 1043.572077 522.7955 Zinc finger protein ZIC 2 OS=Homo sapiens OX=9606 GN=ZIC2 PE=1 SV=2 6 3395.9 - 6.02E+06 - - - -4.1233 - 1.593 0.339 - 125.7 1 2 0 -0.0043 10 0 0 0 7.15E+08 2.33E+08 - - - 2.8432 0.9998 221125_WJC_METTL3_EV_vs_WT_F01.17092.17092.2 0.00521 16-Sep R.YLDVSILGK[136.11].F sp|Q86U44|MTA70_HUMAN 1 1014.5841 0.03 5037 17092 2 1014.583858 508.2993 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 5.83 3396.1 - 4.50E+09 - - - -0.2366 - 1.822 0.471 - 178.8 1 2 0 -0.0002 9 0 0 0 1.79E+10 6.33E+11 - - - 4.2554 0.9905 221125_WJC_METTL3_EV_vs_WT_F01.17094.17094.2 0.00809 18-Oct R.LGLPGEVFGR[166.11].S sp|O95409|ZIC2_HUMAN 1 1053.5847 3.08 5039 17094 2 1053.579457 527.7996 Zinc finger protein ZIC 2 OS=Homo sapiens OX=9606 GN=ZIC2 PE=1 SV=2 6 3396.3 - 3.49E+06 - - - -4.9289 - 1.521 0.375 - 246 1 2 0 -0.0052 10 0 0 0 7.16E+08 2.33E+08 - - - 2.9797 0.8359 221125_WJC_METTL3_EV_vs_WT_F01.17097.17097.2 1.99 12-Jun K.ELEFYLR[166.11].K "sp|P62241|RS8_HUMAN,tr|Q5JR95|Q5JR95_HUMAN" 2 978.505 1 5040 17097 2 978.502102 490.2598 40S ribosomal protein S8 OS=Homo sapiens OX=9606 GN=RPS8 PE=1 SV=2 4.53 3396.7 - 3.76E+06 - - - -2.9647 - 0.979 0.093 - 143.7 1 2 0 -0.0029 7 0 0 0 2.27E+08 2.28E+08 - - - -0.3403 0.9604 221125_WJC_METTL3_EV_vs_WT_F01.17100.17100.2 0.0485 12-Aug K.ELEFYLR.K "sp|P62241|RS8_HUMAN,tr|Q5JR95|Q5JR95_HUMAN" 2 968.4967 1 5041 17100 2 968.492167 485.2556 40S ribosomal protein S8 OS=Homo sapiens OX=9606 GN=RPS8 PE=1 SV=2 4.53 3397.1 - 3.11E+06 - - - -4.7145 - 1.528 0.162 - 260.5 1 2 0 -0.0046 7 0 0 0 2.27E+08 2.28E+08 - - - 1.5794 0.9992 221125_WJC_METTL3_EV_vs_WT_F01.17104.17104.2 0.000637 16-Nov K.LQYEGIFIK.D sp|Q15459|SF3A1_HUMAN 1 1109.6121 0.76 5045 17104 2 1109.609531 555.8133 Splicing factor 3A subunit 1 OS=Homo sapiens OX=9606 GN=SF3A1 PE=1 SV=1 6 3397.5 - 2.74E+06 - - - -2.3125 - 1.866 0.363 - 275.9 1 2 0 -0.0026 9 0 0 0 3.74E+07 4.93E+07 - - - 3.526 0.9986 221125_WJC_METTL3_EV_vs_WT_F01.17109.17109.2 0.00777 14-Aug R.GLFIIDGK[136.11].G sp|P32119|PRDX2_HUMAN 1 869.5102 1.06 5046 17109 2 869.508397 435.7624 Peroxiredoxin-2 OS=Homo sapiens OX=9606 GN=PRDX2 PE=1 SV=5 5.84 3398.2 - 3.29E+06 - - - -2.0782 - 1.511 0.34 - 275 1 2 0 -0.0018 8 0 0 0 5.80E+08 5.46E+08 - - - 2.7966 0.9194 221125_WJC_METTL3_EV_vs_WT_F01.17116.17116.2 0.0136 14-Nov Y.LDVSILGK[136.11].F sp|Q86U44|MTA70_HUMAN 1 851.5208 0.02 5047 17116 2 851.518276 426.7677 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 5.84 3399.3 - 2.88E+06 - - - -2.9277 - 2.056 0.299 - 365.2 1 1 0 -0.0025 8 0 0 0 5.42E+06 2.90E+08 - - - 3.4224 0.9923 221125_WJC_METTL3_EV_vs_WT_F01.17121.17121.2 0.0205 14-Jul R.GLFIIDGK.G sp|P32119|PRDX2_HUMAN 1 861.496 1.06 5049 17121 2 861.492921 431.7553 Peroxiredoxin-2 OS=Homo sapiens OX=9606 GN=PRDX2 PE=1 SV=5 5.84 3399.9 - 6.33E+06 - - - -3.5787 - 1.407 0.297 - 177.3 1 2 0 -0.0031 8 0 0 0 5.80E+08 5.46E+08 - - - 2.2635 0.9984 221125_WJC_METTL3_EV_vs_WT_F01.17134.17134.2 0.00407 20-Oct K.FSPAGPILSIR.L "sp|Q9H361|PABP3_HUMAN,sp|Q5JQF8|PAP1M_HUMAN,sp|Q4VXU2|PAP1L_HUMAN,sp|P11940|PABP1_HUMAN,tr|A0A7I2V3J9|A0A7I2V3J9_HUMAN,tr|A0A7I2V649|A0A7I2V649_HUMAN,tr|A0A6Q8JFT6|A0A6Q8JFT6_HUMAN,tr|E5RHG7|E5RHG7_HUMAN,tr|E5RFD8|E5RFD8_HUMAN,tr|H0YAR2|H0YAR2_HUMAN,tr|E7ERJ7|E7ERJ7_HUMAN,tr|E5RJB9|E5RJB9_HUMAN,tr|A0A7I2YQ88|A0A7I2YQ88_HUMAN,tr|E5RGC4|E5RGC4_HUMAN,tr|E5RH24|E5RH24_HUMAN,tr|H0YBN4|H0YBN4_HUMAN,tr|A0A087WTT1|A0A087WTT1_HUMAN,tr|A0A7I2YQ90|A0A7I2YQ90_HUMAN,tr|A0A6Q8JFV4|A0A6Q8JFV4_HUMAN" 19 1156.6604 1.33 5052 17134 2 1156.655894 579.3375 Polyadenylate-binding protein 3 OS=Homo sapiens OX=9606 GN=PABPC3 PE=1 SV=2 9.75 3401.8 - 4.86E+06 - - - -3.9337 - 1.71 0.5 - 234.4 1 2 0 -0.0046 11 0 0 0 3.52E+09 2.65E+09 - - - 4.1839 0.9967 221125_WJC_METTL3_EV_vs_WT_F01.17145.17145.2 0.000144 20-Nov K.FSPAGPILSIR[166.11].L "sp|Q9H361|PABP3_HUMAN,sp|Q5JQF8|PAP1M_HUMAN,sp|Q4VXU2|PAP1L_HUMAN,sp|P11940|PABP1_HUMAN,tr|A0A7I2V3J9|A0A7I2V3J9_HUMAN,tr|A0A7I2V649|A0A7I2V649_HUMAN,tr|A0A6Q8JFT6|A0A6Q8JFT6_HUMAN,tr|E5RHG7|E5RHG7_HUMAN,tr|E5RFD8|E5RFD8_HUMAN,tr|H0YAR2|H0YAR2_HUMAN,tr|E7ERJ7|E7ERJ7_HUMAN,tr|E5RJB9|E5RJB9_HUMAN,tr|A0A7I2YQ88|A0A7I2YQ88_HUMAN,tr|E5RGC4|E5RGC4_HUMAN,tr|E5RH24|E5RH24_HUMAN,tr|H0YBN4|H0YBN4_HUMAN,tr|A0A087WTT1|A0A087WTT1_HUMAN,tr|A0A7I2YQ90|A0A7I2YQ90_HUMAN,tr|A0A6Q8JFV4|A0A6Q8JFV4_HUMAN" 19 1166.6687 1.33 5055 17145 2 1166.662668 584.3416 Polyadenylate-binding protein 3 OS=Homo sapiens OX=9606 GN=PABPC3 PE=1 SV=2 9.75 3403.3 - 6.90E+06 - - - -5.1823 - 2.134 0.458 - 452.3 1 2 0 -0.006 11 0 0 0 3.52E+09 2.65E+09 - - - 4.4725 0.9964 221125_WJC_METTL3_EV_vs_WT_F01.17152.17152.2 0.275 18-Oct K.ALLAEGVILR.R "sp|Q9Y3D9|RT23_HUMAN,tr|J3QLR8|J3QLR8_HUMAN" 2 1053.6546 1.44 5056 17152 2 1053.650966 527.8346 "28S ribosomal protein S23, mitochondrial OS=Homo sapiens OX=9606 GN=MRPS23 PE=1 SV=2" 6.05 3404.4 - 7.59E+06 - - - -3.4774 - 1.843 0.292 - 278.9 1 2 0 -0.0037 10 0 0 0 6.37E+08 4.43E+08 - - - 2.9032 0.9329 221125_WJC_METTL3_EV_vs_WT_F01.17157.17157.2 0.000907 18-Oct D.TLDNDIMLIK.L "sp|P35030|TRY3_HUMAN,tr|A0A7P0MNE9|A0A7P0MNE9_HUMAN" 2 1174.6268 86.06 5058 17157 2 1174.623009 588.3207 Trypsin-3 OS=Homo sapiens OX=9606 GN=PRSS3 PE=1 SV=2 4.21 3405 - 4.23E+06 - - - -3.1942 - 1.84 0.426 - 182.6 1 1 0 -0.0038 10 0 0 0 1.19E+09 1.38E+07 - - - 3.8883 0.9998 221125_WJC_METTL3_EV_vs_WT_F01.17169.17169.2 0.00207 16-Oct R.YLDVSILGK[136.11].F sp|Q86U44|MTA70_HUMAN 1 1014.5841 0.03 5062 17169 2 1014.583322 508.2993 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 5.83 3406.6 - 7.46E+09 - - - -0.7648 - 1.921 0.475 - 230.9 1 2 0 -0.0008 9 0 0 0 1.79E+10 6.33E+11 - - - 4.4378 0.9929 221125_WJC_METTL3_EV_vs_WT_F01.17170.17170.2 0.0145 14-Jul R.GLFIIDDK[136.11].G "sp|Q06830|PRDX1_HUMAN,sp|Q13162|PRDX4_HUMAN,tr|A0A0A0MRQ5|A0A0A0MRQ5_HUMAN,tr|H7C3T4|H7C3T4_HUMAN,tr|A0A0A0MSI0|A0A0A0MSI0_HUMAN" 5 927.5157 0.65 5063 17170 2 927.514927 464.7651 Peroxiredoxin-1 OS=Homo sapiens OX=9606 GN=PRDX1 PE=1 SV=1 4.21 3406.6 - 4.76E+06 - - - -0.8162 - 1.863 0.002 - 185.5 1 2 0 -0.0008 8 0 0 0 1.62E+09 2.48E+09 - - - 0.932 0.9954 221125_WJC_METTL3_EV_vs_WT_F01.17174.17174.2 8.47E-07 16/28 R.IITGPAPVLPPAALR[166.11].T "sp|Q96PU8|QKI_HUMAN,tr|H0YG47|H0YG47_HUMAN,tr|H0YGD6|H0YGD6_HUMAN" 3 1494.9162 4.15 5065 17174 2 1494.90659 748.4654 Protein quaking OS=Homo sapiens OX=9606 GN=QKI PE=1 SV=1 9.75 3407.1 - 2.94E+06 - - - -6.3984 - 2.631 0.547 - 691.1 1 2 0 -0.0096 15 0 0 0 5.65E+08 1.36E+08 - - - 5.4564 0.9962 221125_WJC_METTL3_EV_vs_WT_F01.17185.17185.2 0.451 13/18 K.ALLAEGVILR[166.11].R "sp|Q9Y3D9|RT23_HUMAN,tr|J3QLR8|J3QLR8_HUMAN" 2 1063.6629 1.44 5067 17185 2 1063.660545 532.8387 "28S ribosomal protein S23, mitochondrial OS=Homo sapiens OX=9606 GN=MRPS23 PE=1 SV=2" 6.05 3408.8 - 1.10E+07 - - - -2.214 - 2.105 0.123 - 822.4 1 2 0 -0.0024 10 0 0 0 6.37E+08 4.43E+08 - - - 2.0263 0.9903 221125_WJC_METTL3_EV_vs_WT_F01.17191.17191.2 7.58E-08 15/26 R.GLLQDDAHPTLVTY.A "sp|Q86U44|MTA70_HUMAN,tr|F5H6D8|F5H6D8_HUMAN,tr|H0YFV6|H0YFV6_HUMAN,tr|B4DTN4|B4DTN4_HUMAN" 4 1541.7726 - 5070 17191 2 1541.769691 771.8936 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 4.2 3409.4 - 3.35E+06 - - - -1.8693 - 2.468 0.594 - 514.4 1 1 0 -0.0029 14 0 0 0 - - - - - 5.6944 0.8349 221125_WJC_METTL3_EV_vs_WT_F01.17207.17207.2 0.261 12-May R.SIFDGFR.D sp|O94888|UBXN7_HUMAN 1 840.413 1.7 5077 17207 2 840.408929 421.2138 UBX domain-containing protein 7 OS=Homo sapiens OX=9606 GN=UBXN7 PE=1 SV=2 5.55 3411.5 - 1.22E+06 - - - -4.8476 - 1.008 0.199 - 96 1 2 0 -0.0041 7 0 0 0 3.48E+07 2.04E+07 - - - 0.5348 0.9964 221125_WJC_METTL3_EV_vs_WT_F01.17211.17211.2 0.0257 12-Aug R.IIFDDFR[166.11].E sp|P46977|STT3A_HUMAN 1 934.4788 1.14 5078 17211 2 934.476134 468.2467 Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit STT3A OS=Homo sapiens OX=9606 GN=STT3A PE=1 SV=2 4.21 3412 - 2.49E+06 - - - -2.8401 - 1.259 0.364 - 153.8 1 2 0 -0.0027 7 0 0 0 1.35E+08 1.19E+08 - - - 2.4584 0.9991 221125_WJC_METTL3_EV_vs_WT_F01.17212.17212.2 0.0402 12-Jul R.ISPWLLR[166.11].V "sp|P24928|RPB1_HUMAN,tr|A0A6Q8PGB0|A0A6Q8PGB0_HUMAN" 2 893.5362 1.34 5079 17212 2 893.535658 447.7754 DNA-directed RNA polymerase II subunit RPB1 OS=Homo sapiens OX=9606 GN=POLR2A PE=1 SV=2 9.75 3412.2 - 752749 - - - -0.6547 - 1.644 0.258 - 202.8 1 2 0 -0.0006 7 0 0 0 5.69E+07 4.25E+07 - - - 2.5216 0.9921 221125_WJC_METTL3_EV_vs_WT_F01.17213.17213.2 0.00821 16-Aug K.FPTLWSGAR.S "sp|Q1KMD3|HNRL2_HUMAN,tr|H3BQZ7|H3BQZ7_HUMAN" 2 1033.5345 1.75 5080 17213 2 1033.528801 517.7745 Heterogeneous nuclear ribonucleoprotein U-like protein 2 OS=Homo sapiens OX=9606 GN=HNRNPUL2 PE=1 SV=1 9.75 3412.3 - 2.46E+06 - - - -5.5286 - 1.839 0.384 - 245.6 1 2 0 -0.0057 9 0 0 0 7.83E+07 4.48E+07 - - - 3.6379 0.9961 221125_WJC_METTL3_EV_vs_WT_F01.17219.17219.2 0.00056 18-Nov K.VGDQILLAIK[136.11].G sp|Q6P1L8|RM14_HUMAN 1 1076.6685 1.12 5083 17219 2 1076.663171 539.3415 "39S ribosomal protein L14, mitochondrial OS=Homo sapiens OX=9606 GN=MRPL14 PE=1 SV=1" 5.81 3413 - 1.76E+06 - - - -4.9458 - 2.015 0.406 - 373.2 1 2 0 -0.0053 10 0 0 0 7.23E+07 6.45E+07 - - - 3.9937 0.9935 221125_WJC_METTL3_EV_vs_WT_F01.17227.17227.2 0.00382 16-Sep R.IMFEVQDLK[136.11].Y "sp|Q14204|DYHC1_HUMAN,tr|A0A7P0T8N2|A0A7P0T8N2_HUMAN,tr|A0A7P0T9C4|A0A7P0T9C4_HUMAN,tr|A0A7P0TBJ7|A0A7P0TBJ7_HUMAN,tr|A0A804HHY6|A0A804HHY6_HUMAN,tr|A0A7P0T9K2|A0A7P0T9K2_HUMAN,tr|A0A7P0TB64|A0A7P0TB64_HUMAN,tr|A0A2R8Y706|A0A2R8Y706_HUMAN,tr|A0A7P0T916|A0A7P0T916_HUMAN,tr|A0A7P0TB75|A0A7P0TB75_HUMAN,tr|A0A7P0T8W5|A0A7P0T8W5_HUMAN,tr|A0A7P0TAF3|A0A7P0TAF3_HUMAN,tr|A0A7P0T9F1|A0A7P0T9F1_HUMAN,tr|A0A7P0TAW9|A0A7P0TAW9_HUMAN,tr|A0A2R8YGC7|A0A2R8YGC7_HUMAN,tr|A0A7P0TA13|A0A7P0TA13_HUMAN,tr|A0A7P0TAV5|A0A7P0TAV5_HUMAN,tr|A0A7P0T7V5|A0A7P0T7V5_HUMAN,tr|A0A7P0T9R4|A0A7P0T9R4_HUMAN,tr|A0A2R8Y5T0|A0A2R8Y5T0_HUMAN,tr|A0A7P0T990|A0A7P0T990_HUMAN,tr|A0A7P0T942|A0A7P0T942_HUMAN,tr|A0A2R8YFZ7|A0A2R8YFZ7_HUMAN,tr|A0A7P0T825|A0A7P0T825_HUMAN,tr|A0A2R8Y6H2|A0A2R8Y6H2_HUMAN,tr|A0A7P0TAM4|A0A7P0TAM4_HUMAN" 26 1129.5933 2.11 5089 17227 2 1129.586746 565.8039 Cytoplasmic dynein 1 heavy chain 1 OS=Homo sapiens OX=9606 GN=DYNC1H1 PE=1 SV=5 4.37 3414 - 804480 - - - -5.7862 - 1.746 0.47 - 245.6 1 2 0 -0.0065 9 0 0 0 1.77E+07 8.42E+06 - - - 4.1227 0.8157 221125_WJC_METTL3_EV_vs_WT_F01.17234.17234.2 0.0207 14-Aug R.FLYSELMK[136.11].Y "sp|P55265|DSRAD_HUMAN,tr|A0A3B3IRQ9|A0A3B3IRQ9_HUMAN,tr|A0A3B3ISU1|A0A3B3ISU1_HUMAN,tr|A0A7P0Z4K3|A0A7P0Z4K3_HUMAN,tr|A0A7P0Z4F9|A0A7P0Z4F9_HUMAN" 5 1037.5347 0.02 5094 17234 2 1037.526899 519.7746 Double-stranded RNA-specific adenosine deaminase OS=Homo sapiens OX=9606 GN=ADAR PE=1 SV=4 6 3414.9 - 1.51E+06 - - - -7.5236 - 1.267 0.267 - 141.5 1 2 0 -0.0078 8 0 0 0 6.57E+06 3.67E+08 - - - 1.7243 0.9568 221125_WJC_METTL3_EV_vs_WT_F01.17236.17236.2 0.0016 18-Jul R.NPEAALSPTF.R "sp|Q86U44|MTA70_HUMAN,tr|B4E349|B4E349_HUMAN,tr|F5H6D8|F5H6D8_HUMAN,tr|B4DTN4|B4DTN4_HUMAN" 4 1045.508 - 5096 17236 2 1045.506055 523.7613 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 4 3415.1 - 4.43E+06 - - - -1.8852 - 1.553 0.413 - 154.9 1 1 0 -0.002 10 0 0 0 - - - - - 3.3195 0.9994 221125_WJC_METTL3_EV_vs_WT_F01.17237.17237.2 0.0715 18-Oct K.VGDQILLAIK.G sp|Q6P1L8|RM14_HUMAN 1 1068.6543 1.1 5097 17237 2 1068.651848 535.3344 "39S ribosomal protein L14, mitochondrial OS=Homo sapiens OX=9606 GN=MRPL14 PE=1 SV=1" 5.81 3415.1 - 3.28E+06 - - - -2.2907 - 1.838 0.437 - 237.6 1 2 0 -0.0024 10 0 0 0 7.23E+07 6.55E+07 - - - 3.9669 0.9124 221125_WJC_METTL3_EV_vs_WT_F01.17238.17238.2 0.343 16-Jun K.ALVDNEQLR.H sp|O75146|HIP1R_HUMAN 1 1056.5564 1.8 5098 17238 2 1056.553112 529.2855 Huntingtin-interacting protein 1-related protein OS=Homo sapiens OX=9606 GN=HIP1R PE=1 SV=2 4.37 3415.2 - 1.64E+06 - - - -3.0864 - 1.333 0.04 - 90.7 1 2 0 -0.0033 9 0 0 0 2.97E+07 1.65E+07 - - - 0.167 0.9995 221125_WJC_METTL3_EV_vs_WT_F01.17239.17239.2 0.00386 18-Oct R.IAEFAFEYAR.N "sp|P50213|IDH3A_HUMAN,tr|H0YL72|H0YL72_HUMAN,tr|H0YMU3|H0YMU3_HUMAN" 3 1215.5924 1.5 5099 17239 2 1215.590868 608.8035 "Isocitrate dehydrogenase [NAD] subunit alpha, mitochondrial OS=Homo sapiens OX=9606 GN=IDH3A PE=1 SV=1" 4.53 3415.4 - 1.06E+06 - - - -1.28 - 2.325 0.258 - 408.3 1 2 0 -0.0016 10 0 0 0 2.32E+07 1.55E+07 - - - 3.3012 0.9994 221125_WJC_METTL3_EV_vs_WT_F01.17242.17242.2 1.37 22-Dec K.TPAILYTYSGLR[166.11].N "sp|Q8N684|CPSF7_HUMAN,tr|C9J323|C9J323_HUMAN,tr|F5H047|F5H047_HUMAN,tr|F5H669|F5H669_HUMAN,tr|F5H6M0|F5H6M0_HUMAN,tr|F5H5B7|F5H5B7_HUMAN,tr|J3QT54|J3QT54_HUMAN,tr|F5H2K8|F5H2K8_HUMAN,tr|F5GXA3|F5GXA3_HUMAN,tr|F5H1W4|F5H1W4_HUMAN,tr|F5H6A8|F5H6A8_HUMAN,tr|C9JM38|C9JM38_HUMAN,tr|C9J286|C9J286_HUMAN,tr|F5H6P5|F5H6P5_HUMAN" 14 1363.7375 1.26 5102 17242 2 1363.732959 682.876 Cleavage and polyadenylation specificity factor subunit 7 OS=Homo sapiens OX=9606 GN=CPSF7 PE=1 SV=1 8.25 3415.7 - 472837 - - - -3.346 - 2.638 0.463 - 694.7 1 2 0 -0.0046 12 0 0 0 4.25E+07 3.36E+07 - - - 5.0116 0.9859 221125_WJC_METTL3_EV_vs_WT_F01.17248.17248.2 0.00115 18-Dec R.IAEFAFEYAR[166.11].N "sp|P50213|IDH3A_HUMAN,tr|H0YL72|H0YL72_HUMAN,tr|H0YMU3|H0YMU3_HUMAN" 3 1225.6007 1.5 5107 17248 2 1225.593602 613.8076 "Isocitrate dehydrogenase [NAD] subunit alpha, mitochondrial OS=Homo sapiens OX=9606 GN=IDH3A PE=1 SV=1" 4.53 3416.5 - 1.07E+06 - - - -5.7866 - 2.325 0.243 - 667.4 1 2 0 -0.0071 10 0 0 0 2.32E+07 1.55E+07 - - - 3.1887 0.9956 221125_WJC_METTL3_EV_vs_WT_F01.17251.17251.2 0.022 14-Sep K.NVFNALIR[166.11].L "sp|Q02978|M2OM_HUMAN,tr|I3L1P8|I3L1P8_HUMAN" 2 955.5479 1.16 5110 17251 2 955.544021 478.7812 Mitochondrial 2-oxoglutarate\malate carrier protein OS=Homo sapiens OX=9606 GN=SLC25A11 PE=1 SV=3 9.75 3416.9 - 489673 - - - -4.0281 - 1.652 0.346 - 252.1 1 2 0 -0.0038 8 0 0 0 1.73E+07 1.48E+07 - - - 3.1093 0.9996 221125_WJC_METTL3_EV_vs_WT_F01.17253.17253.2 7.74E-05 16-Sep K.MIFDVESMK[136.11].K sp|P09874|PARP1_HUMAN 1 1106.5232 1.13 5112 17253 2 1106.524474 554.2689 Poly [ADP-ribose] polymerase 1 OS=Homo sapiens OX=9606 GN=PARP1 PE=1 SV=4 4.37 3417.1 - 385026 - - - 1.1929 - 1.691 0.419 - 240.1 1 2 0 0.0013 9 0 0 0 3.92E+07 3.48E+07 - - - 3.6551 0.9976 221125_WJC_METTL3_EV_vs_WT_F01.17256.17256.2 0.0231 14-Jun K.LMWIPDTK.G sp|P61962|DCAF7_HUMAN 1 1002.5208 1.35 5113 17256 2 1002.521016 502.2677 DDB1- and CUL4-associated factor 7 OS=Homo sapiens OX=9606 GN=DCAF7 PE=1 SV=1 5.84 3417.5 - 7.94E+06 - - - 0.1766 - 1.198 0.282 - 108.8 1 2 0 0.0002 8 0 0 0 2.04E+08 1.51E+08 - - - 1.6686 0.9906 221125_WJC_METTL3_EV_vs_WT_F01.17258.17258.2 0.143 14-Aug K.AGISFIIK.R "sp|P78347|GTF2I_HUMAN,tr|A0A494C1K3|A0A494C1K3_HUMAN" 2 847.5167 1.63 5115 17258 2 847.515716 424.7656 General transcription factor II-I OS=Homo sapiens OX=9606 GN=GTF2I PE=1 SV=2 8.8 3417.7 - 3.55E+06 - - - -1.2082 - 1.347 0.123 - 155.1 1 2 0 -0.001 8 0 0 0 4.38E+07 2.69E+07 - - - 0.8475 0.9991 221125_WJC_METTL3_EV_vs_WT_F01.17259.17259.2 0.0234 12-Jul R.YLNFFTK[136.11].A sp|P12004|PCNA_HUMAN 1 939.4946 1.01 5116 17259 2 939.493932 470.7546 Proliferating cell nuclear antigen OS=Homo sapiens OX=9606 GN=PCNA PE=1 SV=1 8.59 3417.7 - 2.75E+06 - - - -0.6621 - 1.22 0.382 - 134.8 1 2 0 -0.0006 7 0 0 0 9.31E+07 9.22E+07 - - - 2.4923 0.9461 221125_WJC_METTL3_EV_vs_WT_F01.17272.17272.2 3.88 20-Nov K.VLADLAIYEPK[136.11].T sp|Q9BYC9|RM20_HUMAN 1 1238.7002 0.74 5128 17272 2 1238.700619 620.3574 "39S ribosomal protein L20, mitochondrial OS=Homo sapiens OX=9606 GN=MRPL20 PE=1 SV=1" 4.37 3419.2 - 879763 - - - 0.3463 - 1.025 0.059 - 253 1 2 0 0.0004 11 0 0 0 1.30E+07 1.76E+07 - - - -0.4566 0.9814 221125_WJC_METTL3_EV_vs_WT_F01.17274.17274.2 3.09 12-Jun R.LILMDLK.G "sp|Q9BUK6|MSTO1_HUMAN,tr|A0A3B3IUD2|A0A3B3IUD2_HUMAN" 2 844.5092 0.42 5129 17274 2 844.508282 423.2619 Protein misato homolog 1 OS=Homo sapiens OX=9606 GN=MSTO1 PE=1 SV=1 5.84 3419.4 - 3.48E+06 - - - -1.1012 - 1.343 0.051 - 120.1 1 2 0 -0.0009 7 0 0 0 6.45E+07 1.53E+08 - - - 0.3518 0.9997 221125_WJC_METTL3_EV_vs_WT_F01.17277.17277.2 0.000338 22-Nov K.TPAILYTYSGLR.N "sp|Q8N684|CPSF7_HUMAN,tr|C9J323|C9J323_HUMAN,tr|F5H047|F5H047_HUMAN,tr|F5H669|F5H669_HUMAN,tr|F5H6M0|F5H6M0_HUMAN,tr|F5H5B7|F5H5B7_HUMAN,tr|J3QT54|J3QT54_HUMAN,tr|F5H2K8|F5H2K8_HUMAN,tr|F5GXA3|F5GXA3_HUMAN,tr|F5H1W4|F5H1W4_HUMAN,tr|F5H6A8|F5H6A8_HUMAN,tr|C9JM38|C9JM38_HUMAN,tr|C9J286|C9J286_HUMAN,tr|F5H6P5|F5H6P5_HUMAN" 14 1353.7293 1.26 5132 17277 2 1353.727649 677.8719 Cleavage and polyadenylation specificity factor subunit 7 OS=Homo sapiens OX=9606 GN=CPSF7 PE=1 SV=1 8.25 3419.7 - 1.64E+06 - - - -1.1841 - 2.508 0.314 - 489 1 2 0 -0.0016 12 0 0 0 4.25E+07 3.36E+07 - - - 3.779 0.9994 221125_WJC_METTL3_EV_vs_WT_F01.17286.17286.2 6.88E-06 13/22 K.LPVGTTATLYFR.D "sp|Q9NZ01|TECR_HUMAN,tr|M0R2N5|M0R2N5_HUMAN" 2 1337.7343 1.29 5141 17286 2 1337.729581 669.8744 Very-long-chain enoyl-CoA reductase OS=Homo sapiens OX=9606 GN=TECR PE=1 SV=1 8.75 3420.7 - 375030 - - - -3.5553 - 2.592 0.52 - 587.7 1 2 0 -0.0048 12 0 0 0 8.74E+06 6.80E+06 - - - 5.3862 0.9944 221125_WJC_METTL3_EV_vs_WT_F01.17288.17288.2 0.00145 14/18 N.PEAALSPTFR[166.11].S "sp|Q86U44|MTA70_HUMAN,tr|B4E349|B4E349_HUMAN,tr|F5H6D8|F5H6D8_HUMAN,tr|B4DTN4|B4DTN4_HUMAN" 4 1097.5745 0.14 5142 17288 2 1097.574182 549.7945 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 6.43 3420.9 - 7.62E+06 - - - -0.2706 - 2.645 0.49 - 968.7 1 1 0 -0.0003 10 0 0 0 3.73E+07 2.67E+08 - - - 5.3751 0.9963 221125_WJC_METTL3_EV_vs_WT_F01.17290.17290.2 0.184 12-Jun R.YLNFFTK.A sp|P12004|PCNA_HUMAN 1 931.4804 1.01 5143 17290 2 931.479753 466.7475 Proliferating cell nuclear antigen OS=Homo sapiens OX=9606 GN=PCNA PE=1 SV=1 8.59 3421.1 - 5.47E+06 - - - -0.6452 - 1.113 0.269 - 96.2 1 2 0 -0.0006 7 0 0 0 9.31E+07 9.22E+07 - - - 1.3669 0.9984 221125_WJC_METTL3_EV_vs_WT_F01.17291.17291.2 0.081 12-Jun R.IIFDDFR.E sp|P46977|STT3A_HUMAN 1 924.4705 1.01 5144 17291 2 924.469681 463.2425 Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit STT3A OS=Homo sapiens OX=9606 GN=STT3A PE=1 SV=2 4.21 3421.2 - 3.56E+06 - - - -0.9054 - 1.414 0.262 - 98.5 1 2 0 -0.0008 7 0 0 0 1.42E+08 1.41E+08 - - - 2.0735 0.9996 221125_WJC_METTL3_EV_vs_WT_F01.17292.17292.2 0.0032 16-Oct R.LAVLPYELR[166.11].F "sp|Q9ULX3|NOB1_HUMAN,tr|H3BUR4|H3BUR4_HUMAN" 2 1082.6364 0.82 5145 17292 2 1082.63441 542.3255 RNA-binding protein NOB1 OS=Homo sapiens OX=9606 GN=NOB1 PE=1 SV=1 6 3421.2 - 4.75E+06 - - - -1.7928 - 2.157 0.375 - 553 1 2 0 -0.0019 9 0 0 0 1.03E+08 1.25E+08 - - - 4.0341 0.9991 221125_WJC_METTL3_EV_vs_WT_F01.17293.17293.2 0.116 16-Oct R.LAVLPYELR.F "sp|Q9ULX3|NOB1_HUMAN,tr|H3BUR4|H3BUR4_HUMAN" 2 1072.6281 0.82 5146 17293 2 1072.626784 537.3213 RNA-binding protein NOB1 OS=Homo sapiens OX=9606 GN=NOB1 PE=1 SV=1 6 3421.3 - 3.91E+06 - - - -1.2092 - 2.073 0.213 - 518.8 1 2 0 -0.0013 9 0 0 0 1.03E+08 1.25E+08 - - - 2.7228 0.9991 221125_WJC_METTL3_EV_vs_WT_F01.17294.17294.2 0.0102 14-Sep K.WLTLEVC[160.03]R[166.11].E "sp|Q9NR56|MBNL1_HUMAN,sp|Q5VZF2|MBNL2_HUMAN,sp|Q9NUK0|MBNL3_HUMAN,tr|H7C4T5|H7C4T5_HUMAN,tr|A0A0A0MQX8|A0A0A0MQX8_HUMAN,tr|A0A7P0T9I3|A0A7P0T9I3_HUMAN,tr|B1AKI6|B1AKI6_HUMAN,tr|C9JP00|C9JP00_HUMAN,tr|O95205|O95205_HUMAN" 9 1085.5567 1.43 5147 17294 2 1085.55861 543.7856 Muscleblind-like protein 1 OS=Homo sapiens OX=9606 GN=MBNL1 PE=1 SV=2 5.99 3421.4 - 3.60E+06 - - - 1.7401 - 1.779 0.324 - 387 1 2 0 0.0019 8 0 0 0 2.33E+08 1.63E+08 - - - 3.1708 0.9995 221125_WJC_METTL3_EV_vs_WT_F01.17296.17296.2 0.0721 20-Nov R.ELLIIGGVAAR[166.11].D "sp|Q92499|DDX1_HUMAN,tr|A0A7I2V2M5|A0A7I2V2M5_HUMAN,tr|A0A087X2G1|A0A087X2G1_HUMAN,tr|A0A7I2V430|A0A7I2V430_HUMAN,tr|A0A7I2V421|A0A7I2V421_HUMAN,tr|A0A7I2V4F0|A0A7I2V4F0_HUMAN,tr|A0A7I2V4J3|A0A7I2V4J3_HUMAN,tr|A0A087WZ71|A0A087WZ71_HUMAN,tr|A0A7I2YQ77|A0A7I2YQ77_HUMAN" 9 1120.6844 1.3 5149 17296 2 1120.683569 561.3495 ATP-dependent RNA helicase DDX1 OS=Homo sapiens OX=9606 GN=DDX1 PE=1 SV=2 6.1 3421.5 - 2.89E+06 - - - -0.7094 - 2.008 0.29 - 501.7 1 2 0 -0.0008 11 0 0 0 3.56E+08 2.74E+08 - - - 3.0686 0.9995 221125_WJC_METTL3_EV_vs_WT_F01.17297.17297.2 0.0822 20-Nov R.ELLIIGGVAAR.D "sp|Q92499|DDX1_HUMAN,tr|A0A7I2V2M5|A0A7I2V2M5_HUMAN,tr|A0A087X2G1|A0A087X2G1_HUMAN,tr|A0A7I2V430|A0A7I2V430_HUMAN,tr|A0A7I2V421|A0A7I2V421_HUMAN,tr|A0A7I2V4F0|A0A7I2V4F0_HUMAN,tr|A0A7I2V4J3|A0A7I2V4J3_HUMAN,tr|A0A087WZ71|A0A087WZ71_HUMAN,tr|A0A7I2YQ77|A0A7I2YQ77_HUMAN" 9 1110.6761 1.3 5150 17297 2 1110.674986 556.3453 ATP-dependent RNA helicase DDX1 OS=Homo sapiens OX=9606 GN=DDX1 PE=1 SV=2 6.1 3421.6 - 2.78E+06 - - - -0.9976 - 2.253 0.272 - 467.2 1 2 0 -0.0011 11 0 0 0 3.56E+08 2.74E+08 - - - 3.247 0.998 221125_WJC_METTL3_EV_vs_WT_F01.17298.17298.2 0.0232 14-Jun R.AFFSSYLK.S "sp|Q6ZRP7|QSOX2_HUMAN,tr|H0Y430|H0Y430_HUMAN" 2 961.4909 1.24 5151 17298 2 961.492005 481.7527 Sulfhydryl oxidase 2 OS=Homo sapiens OX=9606 GN=QSOX2 PE=1 SV=3 8.63 3421.6 - 1.81E+06 - - - 1.1295 - 1.107 0.366 - 88.9 1 2 0 0.0011 8 0 0 0 4.08E+07 3.30E+07 - - - 2.0505 0.9997 221125_WJC_METTL3_EV_vs_WT_F01.17299.17299.3 0.000443 16/56 R.IITGPAPVLPPAALR.T "sp|Q96PU8|QKI_HUMAN,tr|H0YG47|H0YG47_HUMAN,tr|H0YGD6|H0YGD6_HUMAN" 3 1484.9079 3.39 5152 17299 3 1484.906056 495.9766 Protein quaking OS=Homo sapiens OX=9606 GN=QKI PE=1 SV=1 9.75 3421.7 - 1.34E+06 - - - -1.2317 - 2.519 0.301 - 340.6 1 2 0 -0.0018 15 0 0 0 2.71E+07 7.99E+06 - - - 4.306 0.9906 221125_WJC_METTL3_EV_vs_WT_F01.17301.17301.2 0.085 12-Jul R.NIIFFGK.F sp|P36952|SPB5_HUMAN 1 837.4749 999 5154 17301 2 837.472882 419.7447 Serpin B5 OS=Homo sapiens OX=9606 GN=SERPINB5 PE=1 SV=2 8.75 3422 - 608785 - - - -2.3798 - 1.243 0.226 - 198.5 1 2 0 -0.002 7 0 0 0 3.09E+07 0.00E+00 - - - 1.3989 0.9996 221125_WJC_METTL3_EV_vs_WT_F01.17304.17304.2 0.00473 14-Sep K.WLTLEVC[160.03]R.E "sp|Q9NR56|MBNL1_HUMAN,sp|Q5VZF2|MBNL2_HUMAN,sp|Q9NUK0|MBNL3_HUMAN,tr|H7C4T5|H7C4T5_HUMAN,tr|A0A0A0MQX8|A0A0A0MQX8_HUMAN,tr|A0A7P0T9I3|A0A7P0T9I3_HUMAN,tr|B1AKI6|B1AKI6_HUMAN,tr|C9JP00|C9JP00_HUMAN,tr|O95205|O95205_HUMAN" 9 1075.5485 1.43 5155 17304 2 1075.547261 538.7815 Muscleblind-like protein 1 OS=Homo sapiens OX=9606 GN=MBNL1 PE=1 SV=2 5.99 3422.4 - 5.45E+06 - - - -1.1064 - 1.692 0.402 - 396.4 1 2 0 -0.0012 8 0 0 0 2.33E+08 1.63E+08 - - - 3.5959 0.9997 221125_WJC_METTL3_EV_vs_WT_F01.17305.17305.2 1.62 14-Oct R.IVEVLLIK.D "sp|Q96E39|RMXL1_HUMAN,tr|A0A1B0GUK8|A0A1B0GUK8_HUMAN" 2 925.6212 1.41 5156 17305 2 925.620426 463.8179 "RNA binding motif protein, X-linked-like-1 OS=Homo sapiens OX=9606 GN=RBMXL1 PE=1 SV=1" 6 3422.4 - 3.26E+06 - - - -0.8416 - 1.906 0.351 - 210 1 2 0 -0.0008 8 0 0 0 5.10E+07 3.63E+07 - - - 3.5786 0.9972 221125_WJC_METTL3_EV_vs_WT_F01.17308.17308.2 0.0284 16-Aug R.LIDFLESGK[136.11].T "sp|Q92841|DDX17_HUMAN,tr|A0A5H1ZRQ2|A0A5H1ZRQ2_HUMAN,tr|A0A1X7SBZ2|A0A1X7SBZ2_HUMAN" 3 1028.5634 0.89 5159 17308 2 1028.561074 515.289 Probable ATP-dependent RNA helicase DDX17 OS=Homo sapiens OX=9606 GN=DDX17 PE=1 SV=2 4.37 3422.7 - 2.03E+06 - - - -2.2245 - 1.583 0.257 - 99.2 1 2 0 -0.0023 9 0 0 0 2.09E+08 2.34E+08 - - - 2.2673 0.9311 221125_WJC_METTL3_EV_vs_WT_F01.17310.17310.2 0.145 16-Jul R.ELNLVLSVR[166.11].E "sp|P49327|FAS_HUMAN,tr|A0A0U1RQF0|A0A0U1RQF0_HUMAN" 2 1051.6265 0.62 5161 17310 2 1051.627682 526.8205 Fatty acid synthase OS=Homo sapiens OX=9606 GN=FASN PE=1 SV=3 6.1 3422.9 - 1.13E+06 - - - 1.1097 - 0.904 0.187 - 28.2 19 2 0 0.0012 9 0 0 0 8.91E+06 1.43E+07 - - - -0.4414 0.9999 221125_WJC_METTL3_EV_vs_WT_F01.17311.17311.2 7.05E-05 14/24 R.LAYINPDLALEEK.N sp|P31948|STIP1_HUMAN 1 1487.7872 1.1 5162 17311 2 1487.78598 744.9009 Stress-induced-phosphoprotein 1 OS=Homo sapiens OX=9606 GN=STIP1 PE=1 SV=1 4.14 3423 - 1.04E+06 - - - -0.7938 - 2.522 0.457 - 505.3 1 2 0 -0.0012 13 0 0 0 6.14E+07 5.57E+07 - - - 4.7902 0.9999 221125_WJC_METTL3_EV_vs_WT_F01.17316.17316.2 0.000234 28-Dec R.IITGPAPVLPPAALR.T "sp|Q96PU8|QKI_HUMAN,tr|H0YG47|H0YG47_HUMAN,tr|H0YGD6|H0YGD6_HUMAN" 3 1484.9079 2.49 5165 17316 2 1484.906942 743.4612 Protein quaking OS=Homo sapiens OX=9606 GN=QKI PE=1 SV=1 9.75 3423.7 - 3.13E+06 - - - -0.6351 - 2.215 0.529 - 349.7 1 2 0 -0.0009 15 0 0 0 1.11E+08 4.47E+07 - - - 4.9031 0.9997 221125_WJC_METTL3_EV_vs_WT_F01.17317.17317.2 0.00738 16-Oct R.LIDFLESGK.T "sp|Q92841|DDX17_HUMAN,tr|A0A5H1ZRQ2|A0A5H1ZRQ2_HUMAN,tr|A0A1X7SBZ2|A0A1X7SBZ2_HUMAN" 3 1020.5492 0.89 5166 17317 2 1020.548142 511.2819 Probable ATP-dependent RNA helicase DDX17 OS=Homo sapiens OX=9606 GN=DDX17 PE=1 SV=2 4.37 3423.8 - 2.68E+06 - - - -0.9995 - 1.707 0.425 - 251 1 2 0 -0.001 9 0 0 0 2.09E+08 2.36E+08 - - - 3.7268 0.9993 221125_WJC_METTL3_EV_vs_WT_F01.17319.17319.2 0.000431 13/24 R.LAYINPDLALEEK[136.11].N sp|P31948|STIP1_HUMAN 1 1495.8014 1.1 5168 17319 2 1495.797846 748.908 Stress-induced-phosphoprotein 1 OS=Homo sapiens OX=9606 GN=STIP1 PE=1 SV=1 4.14 3424 - 2.04E+06 - - - -2.3499 - 1.882 0.424 - 370.8 1 2 0 -0.0035 13 0 0 0 6.14E+07 5.57E+07 - - - 3.7945 0.9863 221125_WJC_METTL3_EV_vs_WT_F01.17321.17321.2 1.48 16-Jun R.GAGWLFGAK[136.11].V sp|O00743|PPP6_HUMAN 1 913.4901 0.81 5170 17321 2 913.492289 457.7523 Serine\threonine-protein phosphatase 6 catalytic subunit OS=Homo sapiens OX=9606 GN=PPP6C PE=1 SV=1 8.75 3424.2 - 903601 - - - 2.3547 - 1.201 0.213 - 131.4 1 2 0 0.0022 9 0 0 0 2.00E+07 2.45E+07 - - - 1.1434 1 221125_WJC_METTL3_EV_vs_WT_F01.17322.17322.2 0.000125 13/22 K.LGLDYSYDLAPR.A sp|Q6P4A8|PLBL1_HUMAN 1 1381.6878 999 5171 17322 2 1381.688844 691.8512 Phospholipase B-like 1 OS=Homo sapiens OX=9606 GN=PLBD1 PE=1 SV=2 4.21 3424.4 - 614990 - - - 0.7693 - 2.911 0.565 - 898.8 1 2 0 0.0011 12 0 0 0 1.30E+07 0.00E+00 - - - 6.0252 1 221125_WJC_METTL3_EV_vs_WT_F01.17325.17325.2 1.44E-08 13/18 K.LGDDIDLIVR[166.11].C sp|O15371|EIF3D_HUMAN 1 1137.6269 1.11 5173 17325 2 1137.625774 569.8207 Eukaryotic translation initiation factor 3 subunit D OS=Homo sapiens OX=9606 GN=EIF3D PE=1 SV=1 3.93 3424.7 - 1.62E+07 - - - -0.9977 - 2.812 0.587 - 615.1 1 2 0 -0.0011 10 0 0 0 3.41E+08 3.07E+08 - - - 6.2621 0.9999 221125_WJC_METTL3_EV_vs_WT_F01.17327.17327.2 2.04E-05 20-Nov K.EVFSMAGVVVR.A "sp|P52272|HNRPM_HUMAN,tr|M0R019|M0R019_HUMAN,tr|M0R0N3|M0R0N3_HUMAN,tr|A0A087X0X3|A0A087X0X3_HUMAN,tr|M0QZM1|M0QZM1_HUMAN,tr|M0QYQ7|M0QYQ7_HUMAN,tr|M0R2T0|M0R2T0_HUMAN" 7 1192.6274 1.55 5174 17327 2 1192.627822 597.321 Heterogeneous nuclear ribonucleoprotein M OS=Homo sapiens OX=9606 GN=HNRNPM PE=1 SV=3 6.1 3424.9 - 2.27E+06 - - - 0.3295 - 2.08 0.541 - 506.9 1 2 0 0.0004 11 0 0 0 2.70E+08 1.73E+08 - - - 5.0179 0.9996 221125_WJC_METTL3_EV_vs_WT_F01.17328.17328.2 0.000993 16-Aug K.VNIIPIIAK.A "sp|Q9NVA2|SEP11_HUMAN,sp|Q92599|SEPT8_HUMAN,sp|Q6ZU15|SEP14_HUMAN,sp|Q14141|SEPT6_HUMAN,sp|Q16181|SEPT7_HUMAN,tr|B1AMS2|B1AMS2_HUMAN,tr|A6NMH6|A6NMH6_HUMAN,tr|A0A087X142|A0A087X142_HUMAN,tr|A0A0U1RRH9|A0A0U1RRH9_HUMAN,tr|F8W8I8|F8W8I8_HUMAN,tr|A0A0U1RRE1|A0A0U1RRE1_HUMAN,tr|E7EPK1|E7EPK1_HUMAN,tr|G3V1Q4|G3V1Q4_HUMAN,tr|A6NFQ9|A6NFQ9_HUMAN,tr|E7ES33|E7ES33_HUMAN,tr|C9JV02|C9JV02_HUMAN,tr|D6RGI3|D6RGI3_HUMAN,tr|D6RER5|D6RER5_HUMAN,tr|D6RDU5|D6RDU5_HUMAN" 19 979.643 0.87 5175 17328 2 979.64221 490.8288 Septin-11 OS=Homo sapiens OX=9606 GN=SEPTIN11 PE=1 SV=3 8.72 3425 - 1.18E+06 - - - -0.8095 - 1.655 0.381 - 265.7 1 2 0 -0.0008 9 0 0 0 3.58E+07 4.14E+07 - - - 3.3123 0.9337 221125_WJC_METTL3_EV_vs_WT_F01.17329.17329.2 0.0184 20-Oct R.LAFPSTLASTP.Y "sp|O95785|WIZ_HUMAN,tr|A0A2R8YFV2|A0A2R8YFV2_HUMAN,tr|A0A669KAV7|A0A669KAV7_HUMAN" 3 1103.5863 - 5176 17329 2 1103.586541 552.8004 Protein Wiz OS=Homo sapiens OX=9606 GN=WIZ PE=1 SV=2 5.52 3425.1 - 2.23E+06 - - - 0.2401 - 1.785 0.222 - 302.6 1 1 0 0.0003 11 0 0 0 - - - - - 2.2481 0.9996 221125_WJC_METTL3_EV_vs_WT_F01.17330.17330.2 0.00303 20-Dec K.EVFSMAGVVVR[166.11].A "sp|P52272|HNRPM_HUMAN,tr|M0R019|M0R019_HUMAN,tr|M0R0N3|M0R0N3_HUMAN,tr|A0A087X0X3|A0A087X0X3_HUMAN,tr|M0QZM1|M0QZM1_HUMAN,tr|M0QYQ7|M0QYQ7_HUMAN,tr|M0R2T0|M0R2T0_HUMAN" 7 1202.6357 1.55 5177 17330 2 1202.632963 602.3251 Heterogeneous nuclear ribonucleoprotein M OS=Homo sapiens OX=9606 GN=HNRNPM PE=1 SV=3 6.1 3425.3 - 1.70E+06 - - - -2.275 - 2.133 0.438 - 579.9 1 2 0 -0.0027 11 0 0 0 2.70E+08 1.73E+08 - - - 4.3245 0.9998 221125_WJC_METTL3_EV_vs_WT_F01.17331.17331.2 0.00624 16-Sep K.VNIIPIIAK[136.11].A "sp|Q9NVA2|SEP11_HUMAN,sp|Q92599|SEPT8_HUMAN,sp|Q6ZU15|SEP14_HUMAN,sp|Q14141|SEPT6_HUMAN,sp|Q16181|SEPT7_HUMAN,tr|B1AMS2|B1AMS2_HUMAN,tr|A6NMH6|A6NMH6_HUMAN,tr|A0A087X142|A0A087X142_HUMAN,tr|A0A0U1RRH9|A0A0U1RRH9_HUMAN,tr|F8W8I8|F8W8I8_HUMAN,tr|A0A0U1RRE1|A0A0U1RRE1_HUMAN,tr|E7EPK1|E7EPK1_HUMAN,tr|G3V1Q4|G3V1Q4_HUMAN,tr|A6NFQ9|A6NFQ9_HUMAN,tr|E7ES33|E7ES33_HUMAN,tr|C9JV02|C9JV02_HUMAN,tr|D6RGI3|D6RGI3_HUMAN,tr|D6RER5|D6RER5_HUMAN,tr|D6RDU5|D6RDU5_HUMAN" 19 987.6572 0.87 5178 17331 2 987.656228 494.8359 Septin-11 OS=Homo sapiens OX=9606 GN=SEPTIN11 PE=1 SV=3 8.72 3425.4 - 1.36E+06 - - - -0.9872 - 1.772 0.482 - 296.3 1 2 0 -0.001 9 0 0 0 3.58E+07 4.14E+07 - - - 4.2559 1 221125_WJC_METTL3_EV_vs_WT_F01.17335.17335.2 2.66E-07 18-Nov K.LGDDIDLIVR.C sp|O15371|EIF3D_HUMAN 1 1127.6186 1.11 5181 17335 2 1127.617871 564.8166 Eukaryotic translation initiation factor 3 subunit D OS=Homo sapiens OX=9606 GN=EIF3D PE=1 SV=1 3.93 3425.8 - 1.84E+07 - - - -0.6811 - 2.697 0.562 - 415.1 1 2 0 -0.0008 10 0 0 0 3.41E+08 3.07E+08 - - - 5.9611 0.9989 221125_WJC_METTL3_EV_vs_WT_F01.17337.17337.2 0.00606 14-Aug R.VDEIIWVK[136.11].T sp|Q86U44|MTA70_HUMAN 1 1008.5735 0 5182 17337 2 1008.572555 505.294 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 4.37 3426.1 - 2.32E+06 - - - -0.9697 - 1.598 0.269 - 163.5 1 2 0 -0.001 8 0 0 0 1.19E+05 9.18E+07 - - - 2.4413 0.9949 221125_WJC_METTL3_EV_vs_WT_F01.17338.17338.2 0.141 12-Aug R.WLITLNK.Q "sp|P06730|IF4E_HUMAN,tr|H0Y8J7|H0Y8J7_HUMAN,tr|D6RBW1|D6RBW1_HUMAN" 3 886.5276 1.36 5183 17338 2 886.526306 444.2711 Eukaryotic translation initiation factor 4E OS=Homo sapiens OX=9606 GN=EIF4E PE=1 SV=2 8.75 3426.1 - 2.08E+06 - - - -1.5036 - 1.635 0.11 - 325.1 1 2 0 -0.0013 7 0 0 0 2.85E+08 2.09E+08 - - - 1.4108 0.9992 221125_WJC_METTL3_EV_vs_WT_F01.17339.17339.2 0.000732 16-Oct R.GAGWLFGAK.V sp|O00743|PPP6_HUMAN 1 905.4759 0.81 5184 17339 2 905.473973 453.7452 Serine\threonine-protein phosphatase 6 catalytic subunit OS=Homo sapiens OX=9606 GN=PPP6C PE=1 SV=1 8.75 3426.3 - 1.30E+06 - - - -2.1701 - 1.774 0.372 - 397.6 1 2 0 -0.002 9 0 0 0 2.00E+07 2.45E+07 - - - 3.4464 0.9811 221125_WJC_METTL3_EV_vs_WT_F01.17344.17344.2 0.000972 20-Nov R.IVATKPLYVAL.A "sp|Q9H361|PABP3_HUMAN,sp|P11940|PABP1_HUMAN,tr|A0A7I2YQE4|A0A7I2YQE4_HUMAN,tr|A0A7I2V649|A0A7I2V649_HUMAN,tr|H0YB86|H0YB86_HUMAN,tr|H0YAR2|H0YAR2_HUMAN,tr|E7ERJ7|E7ERJ7_HUMAN,tr|A0A7I2YQ88|A0A7I2YQ88_HUMAN,tr|A0A087WTT1|A0A087WTT1_HUMAN,tr|A0A7I2YQ90|A0A7I2YQ90_HUMAN,tr|A0A7I2V4N4|A0A7I2V4N4_HUMAN,tr|E7EQV3|E7EQV3_HUMAN" 12 1186.7325 1.34 5187 17344 2 1186.733131 594.3735 Polyadenylate-binding protein 3 OS=Homo sapiens OX=9606 GN=PABPC3 PE=1 SV=2 8.59 3426.9 - 809976 - - - 0.493 - 1.95 0.372 - 257.4 1 1 0 0.0006 11 0 0 0 1.46E+08 1.09E+08 - - - 3.595 0.9999 221125_WJC_METTL3_EV_vs_WT_F01.17346.17346.2 1.52E-06 18-Dec R.FGFGFGNGMK[136.11].Q "sp|Q9ULX6|AKP8L_HUMAN,tr|A0A7P0T9N5|A0A7P0T9N5_HUMAN,tr|A0A7P0TAD3|A0A7P0TAD3_HUMAN,tr|V9GZ50|V9GZ50_HUMAN,tr|A0A7P0TBP0|A0A7P0TBP0_HUMAN,tr|A0A7P0TAJ5|A0A7P0TAJ5_HUMAN,tr|A0A7P0TAE3|A0A7P0TAE3_HUMAN,tr|A0A7P0T847|A0A7P0T847_HUMAN" 8 1068.4942 0.75 5189 17346 2 1068.494604 535.2544 A-kinase anchor protein 8-like OS=Homo sapiens OX=9606 GN=AKAP8L PE=1 SV=4 8.75 3427.2 - 1.66E+06 - - - 0.3435 - 2.057 0.568 - 252.7 1 2 0 0.0004 10 0 0 0 2.61E+07 3.46E+07 - - - 5.2494 0.9976 221125_WJC_METTL3_EV_vs_WT_F01.17348.17348.2 0.0167 14-Jul R.AFFSSYLK[136.11].S "sp|Q6ZRP7|QSOX2_HUMAN,tr|H0Y430|H0Y430_HUMAN" 2 969.5051 1.24 5190 17348 2 969.504351 485.7598 Sulfhydryl oxidase 2 OS=Homo sapiens OX=9606 GN=QSOX2 PE=1 SV=3 8.63 3427.4 - 739198 - - - -0.7922 - 1.201 0.287 - 134 1 2 0 -0.0008 8 0 0 0 4.07E+07 3.29E+07 - - - 1.7129 0.9925 221125_WJC_METTL3_EV_vs_WT_F01.17355.17355.2 0.0495 24-Jul K.VLVPLAAPSMSVR.G "sp|Q96RK0|CIC_HUMAN,tr|A0A0A0MQR4|A0A0A0MQR4_HUMAN,tr|I3L2J0|I3L2J0_HUMAN,tr|A0A7P0T9K5|A0A7P0T9K5_HUMAN" 4 1338.7693 3.05 5194 17355 2 1338.766032 670.3919 Protein capicua homolog OS=Homo sapiens OX=9606 GN=CIC PE=1 SV=2 9.72 3428.1 - 173041 - - - -2.4724 - 1.579 0.191 - 179.8 1 2 0 -0.0033 13 0 0 0 3.08E+06 1.01E+06 - - - 1.6231 0.9836 221125_WJC_METTL3_EV_vs_WT_F01.17356.17356.2 1.9 14-Oct K.LASFFLSR[166.11].V "sp|Q8IZL8|PELP1_HUMAN,tr|E7EV54|E7EV54_HUMAN,tr|C9JFV4|C9JFV4_HUMAN,tr|I3L4P1|I3L4P1_HUMAN,tr|I3L445|I3L445_HUMAN" 5 949.5261 0.36 5195 17356 2 949.526032 475.7703 "Proline-, glutamic acid- and leucine-rich protein 1 OS=Homo sapiens OX=9606 GN=PELP1 PE=1 SV=2" 9.75 3428.3 - 760951 - - - -0.0421 - 1.376 0.038 - 272.2 1 2 0 0 8 0 0 0 5.87E+06 1.63E+07 - - - 0.2843 0.9776 221125_WJC_METTL3_EV_vs_WT_F01.17358.17358.2 0.0662 14-Jul R.GLFIIDDK.G "sp|Q06830|PRDX1_HUMAN,sp|Q13162|PRDX4_HUMAN,tr|A0A0A0MRQ5|A0A0A0MRQ5_HUMAN,tr|H7C3T4|H7C3T4_HUMAN,tr|A0A0A0MSI0|A0A0A0MSI0_HUMAN" 5 919.5015 0.76 5197 17358 2 919.501369 460.758 Peroxiredoxin-1 OS=Homo sapiens OX=9606 GN=PRDX1 PE=1 SV=1 4.21 3428.5 - 393735 - - - -0.1251 - 1.394 0.005 - 119.5 1 2 0 -0.0001 8 0 0 0 1.00E+07 1.31E+07 - - - 0.0797 0.9887 221125_WJC_METTL3_EV_vs_WT_F01.17361.17361.2 0.00684 14-Aug K.LILTPFER[166.11].N "sp|Q9H089|LSG1_HUMAN,tr|F8WFC6|F8WFC6_HUMAN" 2 997.5836 0.92 5198 17361 2 997.58823 499.7991 Large subunit GTPase 1 homolog OS=Homo sapiens OX=9606 GN=LSG1 PE=1 SV=2 6 3428.9 - 1.21E+06 - - - 4.6542 - 1.548 0.309 - 174 1 2 0 0.0046 8 0 0 0 4.37E+07 4.75E+07 - - - 2.6397 0.999 221125_WJC_METTL3_EV_vs_WT_F01.17362.17362.2 0.00544 18-Aug R.FGFGFGNGMK.Q "sp|Q9ULX6|AKP8L_HUMAN,tr|A0A7P0T9N5|A0A7P0T9N5_HUMAN,tr|A0A7P0TAD3|A0A7P0TAD3_HUMAN,tr|V9GZ50|V9GZ50_HUMAN,tr|A0A7P0TBP0|A0A7P0TBP0_HUMAN,tr|A0A7P0TAJ5|A0A7P0TAJ5_HUMAN,tr|A0A7P0TAE3|A0A7P0TAE3_HUMAN,tr|A0A7P0T847|A0A7P0T847_HUMAN" 8 1060.48 0.74 5199 17362 2 1060.479773 531.2473 A-kinase anchor protein 8-like OS=Homo sapiens OX=9606 GN=AKAP8L PE=1 SV=4 8.75 3429 - 1.22E+06 - - - -0.2489 - 1.33 0.343 - 62.4 1 2 0 -0.0003 10 0 0 0 2.62E+07 3.53E+07 - - - 2.3703 0.9944 221125_WJC_METTL3_EV_vs_WT_F01.17363.17363.2 0.969 14-Aug K.LILTPFER.N "sp|Q9H089|LSG1_HUMAN,tr|F8WFC6|F8WFC6_HUMAN" 2 987.5753 0.92 5200 17363 2 987.575079 494.7949 Large subunit GTPase 1 homolog OS=Homo sapiens OX=9606 GN=LSG1 PE=1 SV=2 6 3429.1 - 1.96E+06 - - - -0.241 - 1.417 0.126 - 191 1 2 0 -0.0002 8 0 0 0 4.37E+07 4.75E+07 - - - 1.0227 0.9999 221125_WJC_METTL3_EV_vs_WT_F01.17365.17365.3 5.20E-05 Oct-40 K.EVFSMAGVVVR.A "sp|P52272|HNRPM_HUMAN,tr|M0R019|M0R019_HUMAN,tr|M0R0N3|M0R0N3_HUMAN,tr|A0A087X0X3|A0A087X0X3_HUMAN,tr|M0QZM1|M0QZM1_HUMAN,tr|M0QYQ7|M0QYQ7_HUMAN,tr|M0R2T0|M0R2T0_HUMAN" 7 1192.6274 1.59 5202 17365 3 1192.625138 398.5498 Heterogeneous nuclear ribonucleoprotein M OS=Homo sapiens OX=9606 GN=HNRNPM PE=1 SV=3 6.1 3429.3 - 391566 - - - -1.921 - 1.881 0.505 - 154.2 1 2 0 -0.0023 11 0 0 0 6.07E+06 3.83E+06 - - - 5.9645 0.9997 221125_WJC_METTL3_EV_vs_WT_F01.17366.17366.3 0.000627 Oct-40 K.EVFSMAGVVVR[166.11].A "sp|P52272|HNRPM_HUMAN,tr|M0R019|M0R019_HUMAN,tr|M0R0N3|M0R0N3_HUMAN,tr|A0A087X0X3|A0A087X0X3_HUMAN,tr|M0QZM1|M0QZM1_HUMAN,tr|M0QYQ7|M0QYQ7_HUMAN,tr|M0R2T0|M0R2T0_HUMAN" 7 1202.6357 1.59 5203 17366 3 1202.635993 401.8858 Heterogeneous nuclear ribonucleoprotein M OS=Homo sapiens OX=9606 GN=HNRNPM PE=1 SV=3 6.1 3429.4 - 262882 - - - 0.2445 - 1.803 0.368 - 136 1 2 0 0.0003 11 0 0 0 6.07E+06 3.83E+06 - - - 4.3173 0.9997 221125_WJC_METTL3_EV_vs_WT_F01.17369.17369.2 0.0377 16-Sep R.IQDIVGILR[166.11].D "sp|P46087|NOP2_HUMAN,tr|F5H5X6|F5H5X6_HUMAN,tr|F5GYR3|F5GYR3_HUMAN" 3 1035.6316 1.14 5204 17369 2 1035.631024 518.8231 Probable 28S rRNA (cytosine(4447)-C(5))-methyltransferase OS=Homo sapiens OX=9606 GN=NOP2 PE=1 SV=2 5.84 3429.9 - 2.17E+06 - - - -0.5562 - 1.962 0.376 - 246.4 1 2 0 -0.0006 9 0 0 0 3.97E+07 3.49E+07 - - - 3.7678 0.992 221125_WJC_METTL3_EV_vs_WT_F01.17371.17371.2 0.5 14-Jul K.FYEFYLSK[136.11].C "sp|Q14202|ZMYM3_HUMAN,tr|A6NHB5|A6NHB5_HUMAN,tr|A6NHN7|A6NHN7_HUMAN" 3 1103.5419 0.26 5206 17371 2 1103.541033 552.7782 Zinc finger MYM-type protein 3 OS=Homo sapiens OX=9606 GN=ZMYM3 PE=1 SV=2 6 3430.1 - 564129 - - - -0.7838 - 1.125 0.195 - 142 1 2 0 -0.0009 8 0 0 0 2.87E+06 1.11E+07 - - - 0.8362 0.9991 221125_WJC_METTL3_EV_vs_WT_F01.17373.17373.2 0.000569 22-Oct R.LPVPESITGFAR.L "sp|Q8N5K1|CISD2_HUMAN,tr|I3L1N9|I3L1N9_HUMAN,tr|A0A2R8Y540|A0A2R8Y540_HUMAN" 3 1285.703 1.31 5208 17373 2 1285.705488 643.8588 CDGSH iron-sulfur domain-containing protein 2 OS=Homo sapiens OX=9606 GN=CISD2 PE=1 SV=1 6 3430.4 - 515681 - - - 1.9064 - 1.921 0.34 - 115.6 1 2 0 0.0024 12 0 0 0 8.20E+06 6.25E+06 - - - 3.2692 0.9969 221125_WJC_METTL3_EV_vs_WT_F01.17375.17375.2 0.356 14-Aug R.QVLILGLR[166.11].R sp|O94927|HAUS5_HUMAN 1 920.6047 0.52 5210 17375 2 920.60604 461.3096 HAUS augmin-like complex subunit 5 OS=Homo sapiens OX=9606 GN=HAUS5 PE=1 SV=2 9.75 3430.6 - 294219 - - - 1.5023 - 1.54 0.207 - 171.5 1 2 0 0.0014 8 0 0 0 3.46E+06 6.66E+06 - - - 1.8717 0.9996 221125_WJC_METTL3_EV_vs_WT_F01.17381.17381.2 0.000137 14-Sep R.LSVLLGLK.K "sp|Q9H0F7|ARL6_HUMAN,tr|C9IZ13|C9IZ13_HUMAN" 2 841.5637 1.24 5214 17381 2 841.563542 421.7891 ADP-ribosylation factor-like protein 6 OS=Homo sapiens OX=9606 GN=ARL6 PE=1 SV=1 8.75 3431.4 - 719526 - - - -0.1759 - 1.851 0.32 - 205.7 1 2 0 -0.0001 8 0 0 0 7.63E+06 6.16E+06 - - - 3.2615 0.9999 221125_WJC_METTL3_EV_vs_WT_F01.17382.17382.2 4.40E-06 20-Oct K.FATEAAITILR[166.11].L "sp|P17987|TCPA_HUMAN,tr|F5H282|F5H282_HUMAN,tr|E7EQR6|E7EQR6_HUMAN" 3 1214.6898 0.57 5215 17382 2 1214.689923 608.3522 T-complex protein 1 subunit alpha OS=Homo sapiens OX=9606 GN=TCP1 PE=1 SV=1 6 3431.5 - 624252 - - - 0.0659 - 2.275 0.538 - 372.2 1 2 0 0.0001 11 0 0 0 2.86E+08 4.98E+08 - - - 5.2383 0.9996 221125_WJC_METTL3_EV_vs_WT_F01.17384.17384.3 0.0228 Dec-36 R.FSVLLLHGIR[166.11].F "sp|Q96IU4|ABHEB_HUMAN,tr|B4DQI4|B4DQI4_HUMAN,tr|F8W9U3|F8W9U3_HUMAN" 3 1163.7054 1.22 5217 17384 3 1163.704812 388.9091 Protein ABHD14B OS=Homo sapiens OX=9606 GN=ABHD14B PE=1 SV=1 9.76 3431.7 - 463963 - - - -0.5345 - 2.167 0.293 - 146.3 1 2 0 -0.0006 10 0 0 0 6.22E+06 5.10E+06 - - - 4.065 0.9553 221125_WJC_METTL3_EV_vs_WT_F01.17386.17386.2 0.0613 18-Oct N.ALLNSLEFTK[136.11].A "sp|Q14974|IMB1_HUMAN,tr|J3KTM9|J3KTM9_HUMAN" 2 1142.6427 2.18 5219 17386 2 1142.642435 572.3286 Importin subunit beta-1 OS=Homo sapiens OX=9606 GN=KPNB1 PE=1 SV=2 6.05 3432 - 405328 - - - -0.21 - 1.886 0.241 - 255.4 1 1 0 -0.0002 10 0 0 0 2.11E+07 9.64E+06 - - - 2.5919 0.9997 221125_WJC_METTL3_EV_vs_WT_F01.17393.17393.2 10.2 16-Oct R.IQDIVGILR.D "sp|P46087|NOP2_HUMAN,tr|F5H5X6|F5H5X6_HUMAN,tr|F5GYR3|F5GYR3_HUMAN" 3 1025.6233 1.07 5224 17393 2 1025.623824 513.8189 Probable 28S rRNA (cytosine(4447)-C(5))-methyltransferase OS=Homo sapiens OX=9606 GN=NOP2 PE=1 SV=2 5.84 3432.9 - 2.60E+06 - - - 0.4817 - 2.203 0.337 - 308.9 1 2 0 0.0005 9 0 0 0 3.70E+07 3.48E+07 - - - 3.8149 0.9739 221125_WJC_METTL3_EV_vs_WT_F01.17394.17394.2 0.000574 20-Aug R.LVHPGVAEVVF.V "sp|Q9BY77|PDIP3_HUMAN,tr|F6VRR5|F6VRR5_HUMAN" 2 1165.6495 - 5225 17394 2 1165.650916 583.832 Polymerase delta-interacting protein 3 OS=Homo sapiens OX=9606 GN=POLDIP3 PE=1 SV=2 5.24 3433 - 891700 - - - 1.1762 - 1.675 0.42 - 213 1 1 0 0.0014 11 0 0 0 - - - - - 3.5381 0.9998 221125_WJC_METTL3_EV_vs_WT_F01.17397.17397.3 0.017 Dec-36 R.FSVLLLHGIR.F "sp|Q96IU4|ABHEB_HUMAN,tr|B4DQI4|B4DQI4_HUMAN,tr|F8W9U3|F8W9U3_HUMAN" 3 1153.6972 1.22 5228 17397 3 1153.697749 385.573 Protein ABHD14B OS=Homo sapiens OX=9606 GN=ABHD14B PE=1 SV=1 9.76 3433.3 - 688223 - - - 0.5071 - 2.021 0.35 - 183.2 1 2 0 0.0006 10 0 0 0 6.22E+06 5.10E+06 - - - 4.4968 0.9834 221125_WJC_METTL3_EV_vs_WT_F01.17411.17411.2 0.000545 20-Oct R.IVATK[136.11]PLYVAL.A "sp|Q9H361|PABP3_HUMAN,sp|P11940|PABP1_HUMAN,tr|A0A7I2YQE4|A0A7I2YQE4_HUMAN,tr|A0A7I2V649|A0A7I2V649_HUMAN,tr|H0YB86|H0YB86_HUMAN,tr|H0YAR2|H0YAR2_HUMAN,tr|E7ERJ7|E7ERJ7_HUMAN,tr|A0A7I2YQ88|A0A7I2YQ88_HUMAN,tr|A0A087WTT1|A0A087WTT1_HUMAN,tr|A0A7I2YQ90|A0A7I2YQ90_HUMAN,tr|A0A7I2V4N4|A0A7I2V4N4_HUMAN,tr|E7EQV3|E7EQV3_HUMAN" 12 1194.7467 1.34 5240 17411 2 1194.747917 598.3806 Polyadenylate-binding protein 3 OS=Homo sapiens OX=9606 GN=PABPC3 PE=1 SV=2 8.59 3435.2 - 1.00E+07 - - - 0.9801 - 1.787 0.457 - 248 1 1 0 0.0012 11 0 0 0 1.46E+08 1.09E+08 - - - 3.9865 0.9998 221125_WJC_METTL3_EV_vs_WT_F01.17412.17412.2 0.000286 20-Nov K.FATEAAITILR.L "sp|P17987|TCPA_HUMAN,tr|F5H282|F5H282_HUMAN,tr|E7EQR6|E7EQR6_HUMAN" 3 1204.6816 0.57 5241 17412 2 1204.683728 603.3481 T-complex protein 1 subunit alpha OS=Homo sapiens OX=9606 GN=TCP1 PE=1 SV=1 6 3435.2 - 7.60E+06 - - - 1.7889 - 2.454 0.527 - 476.6 1 2 0 0.0022 11 0 0 0 2.86E+08 4.97E+08 - - - 5.3613 0.9982 221125_WJC_METTL3_EV_vs_WT_F01.17414.17414.2 0.00663 18-Jun R.DVEDVPITVE.- sp|Q13895|BYST_HUMAN 1 1114.5394 - 5243 17414 2 1114.541402 558.277 Bystin OS=Homo sapiens OX=9606 GN=BYSL PE=1 SV=3 3.7 3435.3 - 2.00E+06 - - - 1.8097 - 1.333 0.361 - 144.1 1 2 0 0.002 10 0 0 0 - - - - - 2.509 0.9984 221125_WJC_METTL3_EV_vs_WT_F01.17415.17415.2 0.719 16-Sep R.AVDVGAFLR.D "sp|Q96BT3|CENPT_HUMAN,tr|H3BUW2|H3BUW2_HUMAN,tr|H3BTR4|H3BTR4_HUMAN" 3 946.5236 0.42 5244 17415 2 946.521655 474.2691 Centromere protein T OS=Homo sapiens OX=9606 GN=CENPT PE=1 SV=2 5.88 3435.4 - 1.64E+06 - - - -2.0718 - 1.947 0.234 - 326.3 1 2 0 -0.002 9 0 0 0 1.42E+07 3.37E+07 - - - 2.6963 0.999 221125_WJC_METTL3_EV_vs_WT_F01.17416.17416.2 0.119 16-Aug R.AVDVGAFLR[166.11].D "sp|Q96BT3|CENPT_HUMAN,tr|H3BUW2|H3BUW2_HUMAN,tr|H3BTR4|H3BTR4_HUMAN" 3 956.5319 1.29 5245 17416 2 956.530844 479.2732 Centromere protein T OS=Homo sapiens OX=9606 GN=CENPT PE=1 SV=2 5.88 3435.5 - 1.43E+06 - - - -1.0894 - 1.682 0.28 - 239.8 1 2 0 -0.001 9 0 0 0 1.03E+07 8.01E+06 - - - 2.6131 0.9995 221125_WJC_METTL3_EV_vs_WT_F01.17418.17418.2 0.00916 16-Sep R.FLVQLDDYR[166.11].F "sp|Q9HAD4|WDR41_HUMAN,tr|D6RE66|D6RE66_HUMAN,tr|B4DK73|B4DK73_HUMAN,tr|D6RH33|D6RH33_HUMAN,tr|D6RA22|D6RA22_HUMAN,tr|B4DHS8|B4DHS8_HUMAN,tr|D6R9E7|D6R9E7_HUMAN,tr|H0YAA3|H0YAA3_HUMAN,tr|D6RBY6|D6RBY6_HUMAN,tr|H0YAI6|H0YAI6_HUMAN,tr|D6RB94|D6RB94_HUMAN" 11 1177.6007 0.58 5247 17418 2 1177.603171 589.8076 WD repeat-containing protein 41 OS=Homo sapiens OX=9606 GN=WDR41 PE=1 SV=3 4.21 3435.7 - 747378 - - - 2.1034 - 1.847 0.458 - 374.2 1 2 0 0.0025 9 0 0 0 3.93E+06 6.76E+06 - - - 4.1981 0.9998 221125_WJC_METTL3_EV_vs_WT_F01.17419.17419.2 0.000136 20-Sep R.YIVQVSPLGIR.L sp|Q10570|CPSF1_HUMAN 1 1243.7289 0.7 5248 17419 2 1243.730102 622.8717 Cleavage and polyadenylation specificity factor subunit 1 OS=Homo sapiens OX=9606 GN=CPSF1 PE=1 SV=2 8.75 3435.9 - 729854 - - - 1.0002 - 1.965 0.477 - 245.9 1 2 0 0.0012 11 0 0 0 5.13E+06 7.30E+06 - - - 4.3911 0.9995 221125_WJC_METTL3_EV_vs_WT_F01.17421.17421.2 0.0405 14-Aug R.LSVLLGLK[136.11].K "sp|Q9H0F7|ARL6_HUMAN,tr|C9IZ13|C9IZ13_HUMAN" 2 849.5779 1.24 5250 17421 2 849.578455 425.7962 ADP-ribosylation factor-like protein 6 OS=Homo sapiens OX=9606 GN=ARL6 PE=1 SV=1 8.75 3436.1 - 633941 - - - 0.665 - 1.813 0.317 - 120 1 2 0 0.0006 8 0 0 0 7.43E+06 6.01E+06 - - - 3.1766 0.9797 221125_WJC_METTL3_EV_vs_WT_F01.17424.17424.2 1.97 20-Jun K.VGALSTEVLGR.Q "sp|Q8N398|VW5B2_HUMAN,tr|E9PF42|E9PF42_HUMAN" 2 1100.619 4.21 5253 17424 2 1100.618737 551.3168 von Willebrand factor A domain-containing protein 5B2 OS=Homo sapiens OX=9606 GN=VWA5B2 PE=2 SV=3 5.97 3436.5 - 465146 - - - -0.2144 - 1.505 0.018 - 109.7 2 2 0 -0.0002 11 0 0 0 4.23E+06 1.00E+06 - - - 0.1453 0.9999 221125_WJC_METTL3_EV_vs_WT_F01.17425.17425.3 0.00155 13/40 K.FATEAAITILR.L "sp|P17987|TCPA_HUMAN,tr|F5H282|F5H282_HUMAN,tr|E7EQR6|E7EQR6_HUMAN" 3 1204.6816 0.46 5254 17425 3 1204.682142 402.5678 T-complex protein 1 subunit alpha OS=Homo sapiens OX=9606 GN=TCP1 PE=1 SV=1 6 3436.6 - 458986 - - - 0.4723 - 2.131 0.384 - 191.7 1 2 0 0.0006 11 0 0 0 1.18E+07 2.59E+07 - - - 4.9704 0.9988 221125_WJC_METTL3_EV_vs_WT_F01.17429.17429.2 0.896 14-Sep K.ILILQGLK[136.11].Q "sp|Q9UNX4|WDR3_HUMAN,tr|D6RCT0|D6RCT0_HUMAN" 2 904.6201 0.98 5258 17429 2 904.620403 453.3173 WD repeat-containing protein 3 OS=Homo sapiens OX=9606 GN=WDR3 PE=1 SV=1 8.75 3437.1 - 418345 - - - 0.3471 - 1.774 0.203 - 197.9 1 2 0 0.0003 8 0 0 0 1.12E+07 1.15E+07 - - - 2.2691 0.9716 221125_WJC_METTL3_EV_vs_WT_F01.17430.17430.2 0.00351 20-Nov K.SEIEYYAMLAK[136.11].T "sp|P62888|RL30_HUMAN,tr|E5RI99|E5RI99_HUMAN" 2 1324.6464 0.61 5259 17430 2 1325.652062 663.3305 60S ribosomal protein L30 OS=Homo sapiens OX=9606 GN=RPL30 PE=1 SV=2 4.53 3437.2 - 292108 - - - 759.1626 - 1.899 0.391 - 187.5 1 2 0 1.0056 11 0 0 0 2.91E+07 4.76E+07 - - - 3.3481 0.9996 221125_WJC_METTL3_EV_vs_WT_F01.17432.17432.2 0.0122 16-Oct R.YLDVSILGK[136.11].F sp|Q86U44|MTA70_HUMAN 1 1014.5841 0.04 5260 17432 2 1014.585648 508.2993 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 5.83 3437.5 - 3.50E+07 - - - 1.5277 - 1.825 0.445 - 235.8 1 2 0 0.0015 9 0 0 0 1.16E+08 2.90E+09 - - - 4.0677 0.9999 221125_WJC_METTL3_EV_vs_WT_F01.17433.17433.2 1.50E-06 15/28 R.IITGPAPVLPPAALR[166.11].T "sp|Q96PU8|QKI_HUMAN,tr|H0YG47|H0YG47_HUMAN,tr|H0YGD6|H0YGD6_HUMAN" 3 1494.9162 2.53 5261 17433 2 1494.917199 748.4654 Protein quaking OS=Homo sapiens OX=9606 GN=QKI PE=1 SV=1 9.75 3437.6 - 906607 - - - 0.6984 - 2.315 0.582 - 584 1 2 0 0.001 15 0 0 0 3.91E+07 1.55E+07 - - - 5.4031 0.9999 221125_WJC_METTL3_EV_vs_WT_F01.17434.17434.2 0.000278 18-Nov K.IIQLLDDYPK[136.11].C "sp|Q8NHW5|RLA0L_HUMAN,sp|P05388|RLA0_HUMAN,tr|G3V210|G3V210_HUMAN,tr|F8VU65|F8VU65_HUMAN,tr|F8VWS0|F8VWS0_HUMAN,tr|F8VS58|F8VS58_HUMAN,tr|F8VZS0|F8VZS0_HUMAN,tr|F8VRK7|F8VRK7_HUMAN,tr|F8VQY6|F8VQY6_HUMAN" 9 1224.6845 1.13 5262 17434 2 1224.684401 613.3495 60S acidic ribosomal protein P0-like OS=Homo sapiens OX=9606 GN=RPLP0P6 PE=5 SV=1 4.21 3437.7 - 5.02E+06 - - - -0.1135 - 2.34 0.46 - 393.5 1 2 0 -0.0001 10 0 0 0 6.57E+08 5.81E+08 - - - 4.8115 0.9998 221125_WJC_METTL3_EV_vs_WT_F01.17435.17435.3 0.00115 Aug-40 K.FATEAAITILR[166.11].L "sp|P17987|TCPA_HUMAN,tr|F5H282|F5H282_HUMAN,tr|E7EQR6|E7EQR6_HUMAN" 3 1214.6898 0.46 5263 17435 3 1214.690222 405.9039 T-complex protein 1 subunit alpha OS=Homo sapiens OX=9606 GN=TCP1 PE=1 SV=1 6 3437.7 - 3.53E+06 - - - 0.312 - 1.898 0.378 - 96 1 2 0 0.0004 11 0 0 0 1.19E+07 2.60E+07 - - - 4.5746 0.9974 221125_WJC_METTL3_EV_vs_WT_F01.17436.17436.2 0.0629 14-Aug R.LFGALLER[166.11].G sp|Q9BVI4|NOC4L_HUMAN 1 927.5417 1.2 5264 17436 2 927.542987 464.7781 Nucleolar complex protein 4 homolog OS=Homo sapiens OX=9606 GN=NOC4L PE=1 SV=1 6 3437.8 - 2.30E+06 - - - 1.3638 - 1.748 0.166 - 181.6 1 2 0 0.0013 8 0 0 0 4.04E+07 3.36E+07 - - - 1.951 0.9991 221125_WJC_METTL3_EV_vs_WT_F01.17438.17438.2 0.0173 14-Sep R.LFGALLER.G sp|Q9BVI4|NOC4L_HUMAN 1 917.5335 1.2 5266 17438 2 917.533594 459.774 Nucleolar complex protein 4 homolog OS=Homo sapiens OX=9606 GN=NOC4L PE=1 SV=1 6 3437.9 - 1.55E+06 - - - 0.1548 - 1.884 0.213 - 266.9 1 2 0 0.0001 8 0 0 0 4.01E+07 3.35E+07 - - - 2.5245 0.9985 221125_WJC_METTL3_EV_vs_WT_F01.17439.17439.2 0.38 14-Jul R.DILIDPIR.V "sp|Q86XP3|DDX42_HUMAN,tr|A0A0A0MSJ0|A0A0A0MSJ0_HUMAN" 2 953.5546 1.82 5267 17439 2 953.555301 477.7846 ATP-dependent RNA helicase DDX42 OS=Homo sapiens OX=9606 GN=DDX42 PE=1 SV=1 4.21 3438 - 1.15E+06 - - - 0.754 - 1.566 0.239 - 180.2 1 2 0 0.0007 8 0 0 0 2.72E+07 1.50E+07 - - - 2.1588 0.9804 221125_WJC_METTL3_EV_vs_WT_F01.17440.17440.2 2.69E-05 30-Nov K.LLAAYPGASGLGSAAA.A sp|Q9H7S9|ZN703_HUMAN 1 1388.73 - 5268 17440 2 1388.727933 695.3723 Zinc finger protein 703 OS=Homo sapiens OX=9606 GN=ZNF703 PE=1 SV=1 5.52 3438.1 - 909554 - - - -1.474 - 2.098 0.421 - 103.9 1 1 0 -0.002 16 0 0 0 - - - - - 3.9716 0.9929 221125_WJC_METTL3_EV_vs_WT_F01.17445.17445.2 0.23 18-Aug K.LQVLVGDVLK.T "sp|Q9UNQ2|DIM1_HUMAN,tr|A0A494C0G7|A0A494C0G7_HUMAN,tr|B4DRY2|B4DRY2_HUMAN,tr|A0A0C4DGB1|A0A0C4DGB1_HUMAN,tr|A0A7P0T9J1|A0A7P0T9J1_HUMAN,tr|A0A7P0Z4I0|A0A7P0Z4I0_HUMAN,tr|A0A7P0T9Y7|A0A7P0T9Y7_HUMAN,tr|D6RCL3|D6RCL3_HUMAN" 8 1082.6699 0.96 5273 17445 2 1082.672125 542.3422 Probable dimethyladenosine transferase OS=Homo sapiens OX=9606 GN=DIMT1 PE=1 SV=1 5.84 3438.8 - 474447 - - - 2.0126 - 1.644 0.14 - 146.5 1 2 0 0.0022 10 0 0 0 1.85E+06 1.92E+06 - - - 1.462 0.9725 221125_WJC_METTL3_EV_vs_WT_F01.17446.17446.2 0.00586 14-Aug A.FSFYETLR.E "sp|Q9H6R4|NOL6_HUMAN,tr|A0A0A0MRW6|A0A0A0MRW6_HUMAN" 2 1061.5182 1.33 5274 17446 2 1061.518787 531.7664 Nucleolar protein 6 OS=Homo sapiens OX=9606 GN=NOL6 PE=1 SV=2 6 3438.9 - 452510 - - - 0.5567 - 1.551 0.383 - 171.1 1 1 0 0.0006 8 0 0 0 2.11E+06 1.58E+06 - - - 3.1934 0.9998 221125_WJC_METTL3_EV_vs_WT_F01.17447.17447.2 2.97E-09 14/22 R.VFIGNLNTALVK[136.11].K "sp|Q9UKM9|RALY_HUMAN,sp|Q86SE5|RALYL_HUMAN,tr|Q5QPM0|Q5QPM0_HUMAN,tr|Q5QPM2|Q5QPM2_HUMAN,tr|Q5QPM1|Q5QPM1_HUMAN,tr|E5RG71|E5RG71_HUMAN,tr|Q5QPL9|Q5QPL9_HUMAN,tr|B3KT61|B3KT61_HUMAN,tr|E5RIX9|E5RIX9_HUMAN" 9 1295.7693 0 5275 17447 2 1295.772004 648.8919 RNA-binding protein Raly OS=Homo sapiens OX=9606 GN=RALY PE=1 SV=1 8.72 3439 - 411234 - - - 2.1076 - 2.636 0.501 - 502.7 1 2 0 0.0027 12 0 0 0 5.05E+05 1.72E+08 - - - 5.2908 0.9968 221125_WJC_METTL3_EV_vs_WT_F01.17454.17454.2 0.0384 24-May R.VPPVIVLENQGLR.W "sp|Q9Y3B6|EMC9_HUMAN,tr|H0YNH6|H0YNH6_HUMAN" 2 1432.8402 1.18 5281 17454 2 1432.841586 717.4274 ER membrane protein complex subunit 9 OS=Homo sapiens OX=9606 GN=EMC9 PE=1 SV=3 5.97 3439.9 - 128288 - - - 0.968 - 1.27 0.268 - 59 1 2 0 0.0014 13 0 0 0 9.76E+05 8.30E+05 - - - 1.6335 0.9999 221125_WJC_METTL3_EV_vs_WT_F01.17455.17455.2 0.000623 20-Nov R.IVLLDSSLEYK.K "sp|P49368|TCPG_HUMAN,tr|B4DUR8|B4DUR8_HUMAN,tr|Q5SZX6|Q5SZX6_HUMAN" 3 1278.7071 0.25 5282 17455 2 1278.707496 640.3608 T-complex protein 1 subunit gamma OS=Homo sapiens OX=9606 GN=CCT3 PE=1 SV=4 4.37 3439.9 - 3.47E+06 - - - 0.2948 - 2.43 0.511 - 365.1 1 2 0 0.0004 11 0 0 0 5.71E+08 2.31E+09 - - - 5.2171 0.9989 221125_WJC_METTL3_EV_vs_WT_F01.17459.17459.2 0.0455 16-Jul R.FLVQLDDYR.F "sp|Q9HAD4|WDR41_HUMAN,tr|D6RE66|D6RE66_HUMAN,tr|B4DK73|B4DK73_HUMAN,tr|D6RH33|D6RH33_HUMAN,tr|D6RA22|D6RA22_HUMAN,tr|B4DHS8|B4DHS8_HUMAN,tr|D6R9E7|D6R9E7_HUMAN,tr|H0YAA3|H0YAA3_HUMAN,tr|D6RBY6|D6RBY6_HUMAN,tr|H0YAI6|H0YAI6_HUMAN,tr|D6RB94|D6RB94_HUMAN" 11 1167.5924 0.6 5286 17459 2 1167.591711 584.8035 WD repeat-containing protein 41 OS=Homo sapiens OX=9606 GN=WDR41 PE=1 SV=3 4.21 3440.3 - 783304 - - - -0.6107 - 1.481 0.297 - 187.9 1 2 0 -0.0007 9 0 0 0 3.87E+06 6.50E+06 - - - 2.3706 0.9371 221125_WJC_METTL3_EV_vs_WT_F01.17461.17461.2 0.387 22-Jul G.AVAGLALGPILR.L sp|Q8NBP5|MFSD9_HUMAN 1 1149.7234 999 5288 17461 2 1149.723269 575.869 Major facilitator superfamily domain-containing protein 9 OS=Homo sapiens OX=9606 GN=MFSD9 PE=2 SV=2 9.79 3440.6 - 771378 - - - -0.0957 - 1.481 0.297 - 172.7 1 1 0 -0.0001 12 0 0 0 8.01E+06 0.00E+00 - - - 2.2679 0.9935 221125_WJC_METTL3_EV_vs_WT_F01.17465.17465.2 1.49E-06 24-Dec F.LLPVEAVYSVPGR[166.11].G sp|P49411|EFTU_HUMAN 1 1408.7954 1.26 5292 17465 2 1408.795777 705.405 "Elongation factor Tu, mitochondrial OS=Homo sapiens OX=9606 GN=TUFM PE=1 SV=2" 6 3441 - 594767 - - - 0.2882 - 2.195 0.549 - 330.2 1 1 0 0.0004 13 0 0 0 1.98E+07 1.57E+07 - - - 5.1135 0.8503 221125_WJC_METTL3_EV_vs_WT_F01.17470.17470.2 0.0782 12-May R.VVHIMDF.Q "sp|P43243|MATR3_HUMAN,tr|D6RE02|D6RE02_HUMAN,tr|B3KM87|B3KM87_HUMAN,tr|A8MXP9|A8MXP9_HUMAN,tr|D6RAY2|D6RAY2_HUMAN,tr|D6R991|D6R991_HUMAN,tr|A0A0R4J2E8|A0A0R4J2E8_HUMAN,tr|D6RAM9|D6RAM9_HUMAN,tr|D6RIA2|D6RIA2_HUMAN,tr|H0Y8T4|H0Y8T4_HUMAN,tr|D6REM6|D6REM6_HUMAN,tr|D6RBI2|D6RBI2_HUMAN" 12 859.4262 - 5295 17470 2 859.425647 430.7204 Matrin-3 OS=Homo sapiens OX=9606 GN=MATR3 PE=1 SV=2 5.08 3441.7 - 2.84E+06 - - - -0.6551 - 1.18 0.268 - 95.1 1 1 0 -0.0006 7 0 0 0 - - - - - 1.5447 0.9999 221125_WJC_METTL3_EV_vs_WT_F01.17471.17471.2 1.08E-05 20-Dec R.YGLIGLNGIGK[136.11].S "sp|Q9UG63|ABCF2_HUMAN,tr|C9JZV3|C9JZV3_HUMAN,tr|C9JHK9|C9JHK9_HUMAN" 3 1111.6481 0.46 5296 17471 2 1111.646793 556.8313 ATP-binding cassette sub-family F member 2 OS=Homo sapiens OX=9606 GN=ABCF2 PE=1 SV=2 8.59 3441.8 - 1.42E+06 - - - -1.1712 - 2.323 0.554 - 321.7 1 2 0 -0.0013 11 0 0 0 3.16E+07 6.83E+07 - - - 5.4126 0.8473 221125_WJC_METTL3_EV_vs_WT_F01.17473.17473.2 0.189 26-Aug K.LLAAYPGASGLGSA.A sp|Q9H7S9|ZN703_HUMAN 1 1246.6558 - 5298 17473 2 1246.657279 624.3352 Zinc finger protein 703 OS=Homo sapiens OX=9606 GN=ZNF703 PE=1 SV=1 5.52 3442 - 820721 - - - 1.2249 - 1.281 0.287 - 133.6 1 1 0 0.0015 14 0 0 0 - - - - - 1.7817 0.995 221125_WJC_METTL3_EV_vs_WT_F01.17474.17474.2 3.10E-07 24-Dec F.LLPVEAVYSVPGR.G sp|P49411|EFTU_HUMAN 1 1398.7871 1.27 5299 17474 2 1398.78674 700.4008 "Elongation factor Tu, mitochondrial OS=Homo sapiens OX=9606 GN=TUFM PE=1 SV=2" 6 3442.2 - 631416 - - - -0.2581 - 2.244 0.613 - 547.5 1 1 0 -0.0004 13 0 0 0 1.98E+07 1.56E+07 - - - 5.6429 0.9933 221125_WJC_METTL3_EV_vs_WT_F01.17480.17480.2 0.0182 12-Aug R.WLITLNK[136.11].Q "sp|P06730|IF4E_HUMAN,tr|H0Y8J7|H0Y8J7_HUMAN,tr|D6RBW1|D6RBW1_HUMAN" 3 894.5418 1.47 5304 17480 2 894.541252 448.2782 Eukaryotic translation initiation factor 4E OS=Homo sapiens OX=9606 GN=EIF4E PE=1 SV=2 8.75 3442.9 - 1.51E+06 - - - -0.6562 - 1.43 0.104 - 156.2 1 2 0 -0.0006 7 0 0 0 2.82E+07 1.92E+07 - - - 0.9423 0.9992 221125_WJC_METTL3_EV_vs_WT_F01.17482.17482.2 0.0101 14-Aug R.LDTIFFAK[136.11].Q "sp|Q9Y5K5|UCHL5_HUMAN,tr|Q5LJA9|Q5LJA9_HUMAN,tr|Q5LJB0|Q5LJB0_HUMAN,tr|Q5LJA5|Q5LJA5_HUMAN" 4 961.5364 1.64 5305 17482 2 961.534832 481.7755 Ubiquitin carboxyl-terminal hydrolase isozyme L5 OS=Homo sapiens OX=9606 GN=UCHL5 PE=1 SV=3 5.84 3443.1 - 4.59E+06 - - - -1.6505 - 1.794 0.311 - 189.4 1 2 0 -0.0016 8 0 0 0 6.70E+08 4.08E+08 - - - 3.1002 0.9947 221125_WJC_METTL3_EV_vs_WT_F01.17484.17484.2 2.73 14-Aug K.ILILQGLK.Q "sp|Q9UNX4|WDR3_HUMAN,tr|D6RCT0|D6RCT0_HUMAN" 2 896.6059 1 5307 17484 2 896.60523 449.3102 WD repeat-containing protein 3 OS=Homo sapiens OX=9606 GN=WDR3 PE=1 SV=1 8.75 3443.3 - 875613 - - - -0.735 - 1.483 0.12 - 117.1 1 2 0 -0.0007 8 0 0 0 1.12E+07 1.12E+07 - - - 1.1156 0.9996 221125_WJC_METTL3_EV_vs_WT_F01.17486.17486.2 0.00555 16-Sep K.IIGNLLYYR[166.11].Y "sp|P46940|IQGA1_HUMAN,tr|H0YLE8|H0YLE8_HUMAN" 2 1133.6472 0.98 5309 17486 2 1133.647546 567.8309 Ras GTPase-activating-like protein IQGAP1 OS=Homo sapiens OX=9606 GN=IQGAP1 PE=1 SV=1 8.59 3443.5 - 755584 - - - 0.2611 - 1.965 0.312 - 207.2 1 2 0 0.0003 9 0 0 0 3.83E+07 3.93E+07 - - - 3.2996 0.942 221125_WJC_METTL3_EV_vs_WT_F01.17491.17491.2 0.309 18-Jul R.FLLADNLYC[160.03]K.A sp|P61758|PFD3_HUMAN 1 1255.6271 0.74 5312 17491 2 1255.621604 628.8208 Prefoldin subunit 3 OS=Homo sapiens OX=9606 GN=VBP1 PE=1 SV=4 5.83 3444.2 - 1.17E+06 - - - -4.3731 - 1.287 0.184 - 131.3 1 2 0 -0.0055 10 0 0 0 5.51E+07 7.40E+07 - - - 1.1026 0.9999 221125_WJC_METTL3_EV_vs_WT_F01.17492.17492.2 2.54E-05 18-Dec R.LVQNC[160.03]LWTLR.N "sp|P35222|CTNB1_HUMAN,sp|P14923|PLAK_HUMAN,tr|A0A2R8Y6G0|A0A2R8Y6G0_HUMAN,tr|A0A2R8Y5C3|A0A2R8Y5C3_HUMAN,tr|A0A2R8YCH5|A0A2R8YCH5_HUMAN,tr|A0A2R8Y543|A0A2R8Y543_HUMAN,tr|A0A2R8Y750|A0A2R8Y750_HUMAN,tr|B4DGU4|B4DGU4_HUMAN,tr|A0A2R8Y5A3|A0A2R8Y5A3_HUMAN,tr|A0A2R8Y804|A0A2R8Y804_HUMAN,tr|A0A2R8Y5Z1|A0A2R8Y5Z1_HUMAN,tr|A0A2R8Y7Z0|A0A2R8Y7Z0_HUMAN" 12 1301.6914 254.14 5313 17492 2 1301.691038 651.853 Catenin beta-1 OS=Homo sapiens OX=9606 GN=CTNNB1 PE=1 SV=1 8.25 3444.3 - 747060 - - - -0.2988 - 2.18 0.526 - 644 1 2 0 -0.0004 10 0 0 0 3.99E+07 1.57E+05 - - - 5.1012 0.9987 221125_WJC_METTL3_EV_vs_WT_F01.17493.17493.2 0.0186 12-Jul K.ILFFNDK[136.11].S sp|P29084|T2EB_HUMAN 1 903.4946 1.6 5314 17493 2 903.493388 452.7546 Transcription initiation factor IIE subunit beta OS=Homo sapiens OX=9606 GN=GTF2E2 PE=1 SV=1 5.84 3444.4 - 906216 - - - -1.2905 - 1.423 0.304 - 123.5 1 2 0 -0.0012 7 0 0 0 2.62E+07 1.63E+07 - - - 2.4037 0.9998 221125_WJC_METTL3_EV_vs_WT_F01.17497.17497.2 3.22E-05 18-Oct R.LGSVSLIPLR.G "sp|Q96P48|ARAP1_HUMAN,tr|F5GWQ2|F5GWQ2_HUMAN,tr|H0YGD1|H0YGD1_HUMAN,tr|A0A0A0MSJ2|A0A0A0MSJ2_HUMAN,tr|E7EU13|E7EU13_HUMAN" 5 1053.6546 1.91 5318 17497 2 1053.653639 527.8346 "Arf-GAP with Rho-GAP domain, ANK repeat and PH domain-containing protein 1 OS=Homo sapiens OX=9606 GN=ARAP1 PE=1 SV=3" 9.75 3444.9 - 297354 - - - -0.9405 - 2.344 0.366 - 249.1 1 2 0 -0.001 10 0 0 0 1.16E+07 6.06E+06 - - - 4.1218 0.998 221125_WJC_METTL3_EV_vs_WT_F01.17501.17501.2 0.0192 16-Aug R.SSIAGLLLK[136.11].A "sp|Q15149|PLEC_HUMAN,tr|H0YDN1|H0YDN1_HUMAN" 2 908.5786 1.68 5320 17501 2 908.576887 455.2966 Plectin OS=Homo sapiens OX=9606 GN=PLEC PE=1 SV=3 8.47 3445.5 - 702692 - - - -1.9052 - 1.733 0.238 - 129.6 1 2 0 -0.0017 9 0 0 0 6.24E+07 3.72E+07 - - - 2.3891 0.9999 221125_WJC_METTL3_EV_vs_WT_F01.17506.17506.2 1.45E-05 18-Oct K.VEDAMLMFDK[136.11].T "sp|Q96DH6|MSI2H_HUMAN,tr|B4DHE8|B4DHE8_HUMAN,tr|A0A6Q8PGD8|A0A6Q8PGD8_HUMAN,tr|A0A6Q8PF05|A0A6Q8PF05_HUMAN,tr|B4DM51|B4DM51_HUMAN,tr|A0A6Q8PHP1|A0A6Q8PHP1_HUMAN" 6 1205.5552 1.62 5323 17506 2 1205.554916 603.7849 RNA-binding protein Musashi homolog 2 OS=Homo sapiens OX=9606 GN=MSI2 PE=1 SV=1 4.03 3446.1 - 6.62E+06 - - - -0.2206 - 2.282 0.54 - 396.8 1 2 0 -0.0003 10 0 0 0 3.62E+08 2.24E+08 - - - 5.3323 0.9473 221125_WJC_METTL3_EV_vs_WT_F01.17510.17510.2 0.00524 14-Jun L.ATFLALLK.R tr|A0A1B0GTQ7|A0A1B0GTQ7_HUMAN 1 875.548 999 5327 17510 2 875.547114 438.7813 Acid ceramidase OS=Homo sapiens OX=9606 GN=ASAH1 PE=4 SV=1 8.8 3446.5 - 681949 - - - -1.0576 - 1.326 0.37 - 78.3 1 1 0 -0.0009 8 0 0 0 1.59E+07 0.00E+00 - - - 2.6245 0.9986 221125_WJC_METTL3_EV_vs_WT_F01.17516.17516.2 0.16 14-Jul R.LDTIFFAK.Q "sp|Q9Y5K5|UCHL5_HUMAN,tr|Q5LJA9|Q5LJA9_HUMAN,tr|Q5LJB0|Q5LJB0_HUMAN,tr|Q5LJA5|Q5LJA5_HUMAN" 4 953.5222 1.64 5332 17516 2 953.521446 477.7684 Ubiquitin carboxyl-terminal hydrolase isozyme L5 OS=Homo sapiens OX=9606 GN=UCHL5 PE=1 SV=3 5.84 3447.3 - 3.37E+07 - - - -0.8107 - 1.742 0.194 - 172.1 1 2 0 -0.0008 8 0 0 0 6.75E+08 4.11E+08 - - - 2.1476 1 221125_WJC_METTL3_EV_vs_WT_F01.17518.17518.2 0.000569 18-Dec K.VEDAMLMFDK.T "sp|Q96DH6|MSI2H_HUMAN,tr|B4DHE8|B4DHE8_HUMAN,tr|A0A6Q8PGD8|A0A6Q8PGD8_HUMAN,tr|A0A6Q8PF05|A0A6Q8PF05_HUMAN,tr|B4DM51|B4DM51_HUMAN,tr|A0A6Q8PHP1|A0A6Q8PHP1_HUMAN" 6 1197.541 1.62 5333 17518 2 1197.541772 599.7778 RNA-binding protein Musashi homolog 2 OS=Homo sapiens OX=9606 GN=MSI2 PE=1 SV=1 4.03 3447.5 - 1.44E+07 - - - 0.6597 - 2.466 0.588 - 597.6 1 2 0 0.0008 10 0 0 0 3.63E+08 2.24E+08 - - - 5.9031 0.9994 221125_WJC_METTL3_EV_vs_WT_F01.17519.17519.2 0.00469 16-Aug R.AVALYFIDK.L "sp|P11387|TOP1_HUMAN,sp|Q969P6|TOP1M_HUMAN,tr|A0A7P0T852|A0A7P0T852_HUMAN,tr|E5RIC7|E5RIC7_HUMAN" 4 1038.575 0.75 5334 17519 2 1038.574319 520.2948 DNA topoisomerase 1 OS=Homo sapiens OX=9606 GN=TOP1 PE=1 SV=2 5.88 3447.5 - 4.29E+06 - - - -0.6393 - 1.78 0.3 - 211.9 1 2 0 -0.0007 9 0 0 0 6.17E+07 8.22E+07 - - - 2.9248 0.9987 221125_WJC_METTL3_EV_vs_WT_F01.17521.17521.2 0.0552 16-Sep R.SSIAGLLLK.A "sp|Q15149|PLEC_HUMAN,tr|H0YDN1|H0YDN1_HUMAN" 2 900.5644 1.68 5336 17521 2 900.564139 451.2895 Plectin OS=Homo sapiens OX=9606 GN=PLEC PE=1 SV=3 8.47 3447.7 - 2.10E+06 - - - -0.3098 - 1.457 0.277 - 181.6 1 2 0 -0.0003 9 0 0 0 6.24E+07 3.72E+07 - - - 2.1757 0.8583 221125_WJC_METTL3_EV_vs_WT_F01.17523.17523.2 1.05 14-Sep L.LTITTPLK.N "sp|Q8NEM8|CBPC3_HUMAN,tr|F8W7R4|F8W7R4_HUMAN" 2 885.5535 160 5338 17523 2 885.553743 443.784 Cytosolic carboxypeptidase 3 OS=Homo sapiens OX=9606 GN=AGBL3 PE=2 SV=2 8.75 3447.8 - 1.21E+06 - - - 0.2529 - 1.673 0.132 - 191.4 1 1 0 0.0002 8 0 0 0 8.80E+07 5.50E+05 - - - 1.5679 1 221125_WJC_METTL3_EV_vs_WT_F01.17525.17525.2 4.81E-08 18-Dec K.VDDAMLMFDK.T "sp|O43347|MSI1H_HUMAN,tr|H0YHB7|H0YHB7_HUMAN" 2 1183.5253 1.41 5340 17525 2 1183.531402 592.7699 RNA-binding protein Musashi homolog 1 OS=Homo sapiens OX=9606 GN=MSI1 PE=1 SV=1 3.93 3448.1 - 518261 - - - 5.1287 - 2.638 0.615 - 559.6 1 2 0 0.0061 10 0 0 0 4.69E+08 3.32E+08 - - - 6.2891 0.9999 221125_WJC_METTL3_EV_vs_WT_F01.17532.17532.2 5.33E-06 22-Dec R.IGPLSPFTNAYR.R "sp|O75486|SUPT3_HUMAN,tr|A0A6I8PRV1|A0A6I8PRV1_HUMAN" 2 1334.6983 3.9 5345 17532 2 1334.696295 668.3564 Transcription initiation protein SPT3 homolog OS=Homo sapiens OX=9606 GN=SUPT3H PE=1 SV=3 8.75 3448.9 - 1.83E+06 - - - -1.4917 - 2.342 0.552 - 382.7 1 2 0 -0.002 12 0 0 0 8.44E+07 2.16E+07 - - - 5.3566 0.9992 221125_WJC_METTL3_EV_vs_WT_F01.17534.17534.2 0.00867 16-Sep R.FLSPEFIPR[166.11].R "sp|P49406|RM19_HUMAN,tr|A0A0A0MRF4|A0A0A0MRF4_HUMAN" 2 1114.6051 1.13 5347 17534 2 1114.604358 558.3098 "39S ribosomal protein L19, mitochondrial OS=Homo sapiens OX=9606 GN=MRPL19 PE=1 SV=2" 6 3449.1 - 2.90E+06 - - - -0.6217 - 1.487 0.334 - 334.4 1 2 0 -0.0007 9 0 0 0 5.59E+07 4.94E+07 - - - 2.6556 0.9999 221125_WJC_METTL3_EV_vs_WT_F01.17542.17542.2 7.52E-07 20-Oct K.LTPVPDSFFAK.H sp|O94906|PRP6_HUMAN 1 1220.6441 3.16 5353 17542 2 1220.642577 611.3293 Pre-mRNA-processing factor 6 OS=Homo sapiens OX=9606 GN=PRPF6 PE=1 SV=1 5.84 3450 - 7.20E+06 - - - -1.2682 - 1.942 0.586 - 257.5 1 2 0 -0.0015 11 0 0 0 1.84E+08 5.82E+07 - - - 5.1642 0.9997 221125_WJC_METTL3_EV_vs_WT_F01.17549.17549.2 0.000901 14-Jun R.GYMMMFPR.V "sp|O14654|IRS4_HUMAN,tr|A0A804CF45|A0A804CF45_HUMAN" 2 1031.4391 0.53 5358 17549 2 1031.43869 516.7268 Insulin receptor substrate 4 OS=Homo sapiens OX=9606 GN=IRS4 PE=1 SV=1 8.75 3450.9 - 635222 - - - -0.3975 - 1.385 0.49 - 101.5 1 2 0 -0.0004 8 0 0 0 2.14E+07 4.07E+07 - - - 3.6423 0.9972 221125_WJC_METTL3_EV_vs_WT_F01.17550.17550.2 0.242 16-Jul R.LLESMIPIK[136.11].M "sp|Q9GZM5|YIPF3_HUMAN,tr|D6RGY8|D6RGY8_HUMAN,tr|E7EQR8|E7EQR8_HUMAN,tr|H0Y9A1|H0Y9A1_HUMAN,tr|D6RFI3|D6RFI3_HUMAN" 5 1050.6239 1.45 5359 17550 2 1050.624564 526.3192 Protein YIPF3 OS=Homo sapiens OX=9606 GN=YIPF3 PE=1 SV=1 6 3450.9 - 966579 - - - 0.6758 - 1.476 0.198 - 100.6 1 2 0 0.0007 9 0 0 0 5.29E+07 3.64E+07 - - - 1.6296 0.9994 221125_WJC_METTL3_EV_vs_WT_F01.17552.17552.2 0.000151 16-Oct K.NFDMVIVYK.D sp|Q9Y5B9|SP16H_HUMAN 1 1127.5685 0.43 5361 17552 2 1127.569889 564.7915 FACT complex subunit SPT16 OS=Homo sapiens OX=9606 GN=SUPT16H PE=1 SV=1 5.83 3451.2 - 645384 - - - 1.2168 - 1.417 0.423 - 283.8 1 2 0 0.0014 9 0 0 0 7.83E+06 1.82E+07 - - - 3.1732 0.9311 221125_WJC_METTL3_EV_vs_WT_F01.17554.17554.2 0.00529 18-Sep K.LPVATDFEFK.L "sp|Q96EK7|F120B_HUMAN,tr|A0A0D9SEJ5|A0A0D9SEJ5_HUMAN,tr|F5GY05|F5GY05_HUMAN" 3 1165.6019 0.61 5363 17554 2 1165.60638 583.8082 Constitutive coactivator of peroxisome proliferator-activated receptor gamma OS=Homo sapiens OX=9606 GN=FAM120B PE=1 SV=1 4.37 3451.4 - 307357 - - - 3.8212 - 1.645 0.038 - 193.9 1 2 0 0.0045 10 0 0 0 1.97E+06 3.24E+06 - - - 0.7096 0.9993 221125_WJC_METTL3_EV_vs_WT_F01.17560.17560.2 4.52E-05 18-Nov R.FLLADNLYC[160.03]K[136.11].A sp|P61758|PFD3_HUMAN 1 1263.6413 0.9 5367 17560 2 1263.6373 632.8279 Prefoldin subunit 3 OS=Homo sapiens OX=9606 GN=VBP1 PE=1 SV=4 5.83 3452.1 - 1.58E+06 - - - -3.1615 - 2.136 0.481 - 379 1 2 0 -0.004 10 0 0 0 6.79E+07 7.53E+07 - - - 4.7108 0.9902 221125_WJC_METTL3_EV_vs_WT_F01.17563.17563.2 0.00867 18-Oct R.LITTQQWLIK[136.11].L sp|P00846|ATP6_HUMAN 1 1250.7478 0.93 5370 17563 2 1250.741594 626.3812 ATP synthase subunit a OS=Homo sapiens OX=9606 GN=MT-ATP6 PE=1 SV=1 8.75 3452.4 - 911694 - - - -4.969 - 1.878 0.294 - 310.5 1 2 0 -0.0062 10 0 0 0 1.18E+07 1.27E+07 - - - 2.9696 0.9998 221125_WJC_METTL3_EV_vs_WT_F01.17568.17568.2 5.17E-07 18-Nov K.VDDAMLMFDK[136.11].T "sp|O43347|MSI1H_HUMAN,tr|H0YHB7|H0YHB7_HUMAN" 2 1191.5395 1.41 5373 17568 2 1191.538827 596.777 RNA-binding protein Musashi homolog 1 OS=Homo sapiens OX=9606 GN=MSI1 PE=1 SV=1 3.93 3453.1 - 1.06E+07 - - - -0.5917 - 2.532 0.393 - 775 1 2 0 -0.0007 10 0 0 0 4.70E+08 3.32E+08 - - - 4.5366 0.8174 221125_WJC_METTL3_EV_vs_WT_F01.17571.17571.2 1.01 12-Sep A.IFEILEK[136.11].S "sp|P22234|PUR6_HUMAN,sp|O60264|SMCA5_HUMAN,sp|P28370|SMCA1_HUMAN,tr|A0A0A0MRP6|A0A0A0MRP6_HUMAN,tr|B7ZLQ5|B7ZLQ5_HUMAN,tr|D6RF62|D6RF62_HUMAN,tr|E9PBS1|E9PBS1_HUMAN" 7 898.5255 0.86 5376 17571 2 898.525754 450.27 Multifunctional protein ADE2 OS=Homo sapiens OX=9606 GN=PAICS PE=1 SV=3 4.53 3453.3 - 2.46E+06 - - - 0.2604 - 1.81 0.057 - 244.6 1 1 0 0.0002 7 0 0 0 9.19E+07 1.07E+08 - - - 1.3419 0.9959 221125_WJC_METTL3_EV_vs_WT_F01.17572.17572.2 0.272 14-Aug R.ADLIAYLK.K "sp|P99999|CYC_HUMAN,tr|C9JFR7|C9JFR7_HUMAN" 2 905.5222 1.76 5377 17572 2 905.521211 453.7684 Cytochrome c OS=Homo sapiens OX=9606 GN=CYCS PE=1 SV=2 5.88 3453.3 - 2.32E+06 - - - -1.1132 - 1.764 0.089 - 204.6 1 2 0 -0.001 8 0 0 0 5.68E+07 3.22E+07 - - - 1.4098 0.9978 221125_WJC_METTL3_EV_vs_WT_F01.17573.17573.2 0.102 16-Aug R.LLESMIPIK.M "sp|Q9GZM5|YIPF3_HUMAN,tr|D6RGY8|D6RGY8_HUMAN,tr|E7EQR8|E7EQR8_HUMAN,tr|H0Y9A1|H0Y9A1_HUMAN,tr|D6RFI3|D6RFI3_HUMAN" 5 1042.6097 1.58 5378 17573 2 1042.611113 522.3121 Protein YIPF3 OS=Homo sapiens OX=9606 GN=YIPF3 PE=1 SV=1 6 3453.4 - 2.05E+06 - - - 1.3994 - 1.442 0.272 - 157.3 1 2 0 0.0015 9 0 0 0 5.77E+07 3.64E+07 - - - 2.1085 0.984 221125_WJC_METTL3_EV_vs_WT_F01.17574.17574.2 2.53E-06 Dec-32 K.LLAAYPGASGLGSAAAA.A sp|Q9H7S9|ZN703_HUMAN 1 1459.7671 - 5379 17574 2 1459.764047 730.8908 Zinc finger protein 703 OS=Homo sapiens OX=9606 GN=ZNF703 PE=1 SV=1 5.52 3453.5 - 1.50E+06 - - - -2.0873 - 2.437 0.497 - 376.7 1 1 0 -0.003 17 0 0 0 - - - - - 4.9009 0.9998 221125_WJC_METTL3_EV_vs_WT_F01.17575.17575.2 0.000145 18-Sep R.EC[160.03]LNLWGYER[166.11].V sp|Q86U44|MTA70_HUMAN 1 1348.6109 0.26 5380 17575 2 1348.609059 675.3127 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 4.53 3453.6 - 1.19E+06 - - - -1.3955 - 1.875 0.505 - 416.1 1 2 0 -0.0019 10 0 0 0 5.96E+06 2.33E+07 - - - 4.525 0.9994 221125_WJC_METTL3_EV_vs_WT_F01.17576.17576.2 0.00943 18-Nov K.EVLLVALGSR[166.11].Q sp|Q10570|CPSF1_HUMAN 1 1065.6422 0.84 5381 17576 2 1065.64072 533.8284 Cleavage and polyadenylation specificity factor subunit 1 OS=Homo sapiens OX=9606 GN=CPSF1 PE=1 SV=2 6.1 3453.7 - 1.06E+06 - - - -1.356 - 2.114 0.272 - 429.2 1 2 0 -0.0014 10 0 0 0 3.50E+07 4.19E+07 - - - 3.1391 0.9998 221125_WJC_METTL3_EV_vs_WT_F01.17580.17580.2 8.54E-06 16/28 R.IITGPAPVLPPAALR.T "sp|Q96PU8|QKI_HUMAN,tr|H0YG47|H0YG47_HUMAN,tr|H0YGD6|H0YGD6_HUMAN" 3 1484.9079 2.73 5384 17580 2 1484.910311 743.4612 Protein quaking OS=Homo sapiens OX=9606 GN=QKI PE=1 SV=1 9.75 3454.2 - 2.17E+06 - - - 1.6338 - 2.465 0.581 - 573.5 1 2 0 0.0024 15 0 0 0 6.34E+07 2.32E+07 - - - 5.5496 0.8882 221125_WJC_METTL3_EV_vs_WT_F01.17582.17582.2 3.28 18-Jul R.TVSVGLTLLR.V sp|Q8TEM1|PO210_HUMAN 1 1057.6495 1.84 5385 17582 2 1057.652117 529.832 Nuclear pore membrane glycoprotein 210 OS=Homo sapiens OX=9606 GN=NUP210 PE=1 SV=3 9.41 3454.4 - 1.46E+06 - - - 2.4318 - 1.083 0.062 - 104.6 1 2 0 0.0026 10 0 0 0 3.19E+07 1.74E+07 - - - -0.2793 0.9992 221125_WJC_METTL3_EV_vs_WT_F01.17584.17584.2 0.00142 18-Oct K.VLALLDVPDK[136.11].S sp|Q9NX62|IMPA3_HUMAN 1 1089.6525 3.69 5387 17584 2 1089.651113 545.8335 "Golgi-resident adenosine 3',5'-bisphosphate 3'-phosphatase OS=Homo sapiens OX=9606 GN=BPNT2 PE=1 SV=1" 4.21 3454.7 - 752567 - - - -1.283 - 2.174 0.229 - 383.6 1 2 0 -0.0014 10 0 0 0 1.99E+08 5.41E+07 - - - 2.8996 0.9997 221125_WJC_METTL3_EV_vs_WT_F01.17585.17585.2 0.00294 22-Sep R.IIYVPLPDAATR.R "sp|Q8NB90|AFG2H_HUMAN,tr|A0A6Q8PGU6|A0A6Q8PGU6_HUMAN" 2 1327.75 2.08 5388 17585 2 1327.748618 664.8823 ATPase family protein 2 homolog OS=Homo sapiens OX=9606 GN=SPATA5 PE=1 SV=3 5.84 3454.8 - 591106 - - - -1.0311 - 1.795 0.419 - 226.1 1 2 0 -0.0014 12 0 0 0 1.34E+07 6.42E+06 - - - 3.6746 0.9999 221125_WJC_METTL3_EV_vs_WT_F01.17592.17592.2 3.64E-05 15/24 K.VLATTFDPYLGGR[166.11].N "sp|O95757|HS74L_HUMAN,tr|D6RJ96|D6RJ96_HUMAN,tr|E9PDE8|E9PDE8_HUMAN" 3 1418.7433 0.15 5393 17592 2 1418.743162 710.3789 Heat shock 70 kDa protein 4L OS=Homo sapiens OX=9606 GN=HSPA4L PE=1 SV=3 5.81 3455.7 - 1.05E+06 - - - -0.1219 - 2.894 0.443 - 544.4 1 2 0 -0.0002 13 0 0 0 3.11E+07 2.07E+08 - - - 5.0402 0.9955 221125_WJC_METTL3_EV_vs_WT_F01.17600.17600.2 14.5 12-Sep R.LLDFLQK.R "sp|Q8NEM7|SP20H_HUMAN,tr|B4E2D5|B4E2D5_HUMAN,tr|R4GND2|R4GND2_HUMAN,tr|F6S7C4|F6S7C4_HUMAN" 4 875.5117 1.15 5397 17600 2 875.510294 438.7631 Transcription factor SPT20 homolog OS=Homo sapiens OX=9606 GN=SUPT20H PE=1 SV=2 5.84 3456.7 - 811678 - - - -1.5534 - 1.607 0.134 - 197.2 1 2 0 -0.0014 7 0 0 0 1.34E+08 1.17E+08 - - - 1.5334 0.9945 221125_WJC_METTL3_EV_vs_WT_F01.17604.17604.2 0.983 14-Jul K.NLEIELLK[136.11].L "sp|Q9NVX0|HAUS2_HUMAN,tr|H3BP24|H3BP24_HUMAN,tr|J3QT48|J3QT48_HUMAN,tr|H3BQU2|H3BQU2_HUMAN,tr|H3BP16|H3BP16_HUMAN" 5 978.5841 0.67 5401 17604 2 978.584082 490.2993 HAUS augmin-like complex subunit 2 OS=Homo sapiens OX=9606 GN=HAUS2 PE=1 SV=1 4.53 3457.3 - 344117 - - - -0.0164 - 1.476 0.128 - 116.7 2 2 0 0 8 0 0 0 4.52E+06 6.73E+06 - - - 1.0262 0.9956 221125_WJC_METTL3_EV_vs_WT_F01.17609.17609.2 2.44 12-Aug R.ALLFIPR.R "sp|P08238|HS90B_HUMAN,sp|O00585|CCL21_HUMAN,tr|Q5VZ73|Q5VZ73_HUMAN" 3 828.5222 0.78 5404 17609 2 828.520917 415.2684 Heat shock protein HSP 90-beta OS=Homo sapiens OX=9606 GN=HSP90AB1 PE=1 SV=4 9.79 3457.8 - 2.56E+06 - - - -1.4991 - 1.585 0.156 - 270 2 2 0 -0.0012 7 0 0 0 4.10E+08 5.29E+08 - - - 1.5177 0.911 221125_WJC_METTL3_EV_vs_WT_F01.17610.17610.2 1.17 14-Jul K.IISLDAWR[166.11].V "sp|Q8IZH2|XRN1_HUMAN,tr|H7C5E4|H7C5E4_HUMAN" 2 982.5475 1.75 5405 17610 2 982.543805 492.281 5'-3' exoribonuclease 1 OS=Homo sapiens OX=9606 GN=XRN1 PE=1 SV=1 5.84 3457.9 - 765878 - - - -3.7973 - 1.208 0.12 - 110.9 1 2 0 -0.0037 8 0 0 0 8.01E+07 4.58E+07 - - - 0.4961 0.9919 221125_WJC_METTL3_EV_vs_WT_F01.17611.17611.3 0.000391 13/56 R.IITGPAPVLPPAALR.T "sp|Q96PU8|QKI_HUMAN,tr|H0YG47|H0YG47_HUMAN,tr|H0YGD6|H0YGD6_HUMAN" 3 1484.9079 3.26 5406 17611 3 1484.91137 495.9766 Protein quaking OS=Homo sapiens OX=9606 GN=QKI PE=1 SV=1 9.75 3458.1 - 675895 - - - 2.3469 - 2.543 0.136 - 207.1 1 2 0 0.0035 15 0 0 0 1.58E+07 4.85E+06 - - - 2.4907 0.9997 221125_WJC_METTL3_EV_vs_WT_F01.17616.17616.2 8.62E-05 20-Nov R.LLALNSLYSPK[136.11].L sp|P78527|PRKDC_HUMAN 1 1225.7162 0.85 5409 17616 2 1225.717933 613.8654 DNA-dependent protein kinase catalytic subunit OS=Homo sapiens OX=9606 GN=PRKDC PE=1 SV=3 8.59 3458.6 - 1.81E+06 - - - 1.4351 - 2.194 0.449 - 334.6 1 2 0 0.0018 11 0 0 0 4.60E+07 5.42E+07 - - - 4.4823 0.9983 221125_WJC_METTL3_EV_vs_WT_F01.17618.17618.2 0.051 14-Sep R.VVDLLVIK.G "sp|P56556|NDUA6_HUMAN,tr|R4GN43|R4GN43_HUMAN,tr|A0A2Y9D025|A0A2Y9D025_HUMAN" 3 897.5899 1.47 5411 17618 2 897.588198 449.8022 NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 6 OS=Homo sapiens OX=9606 GN=NDUFA6 PE=1 SV=4 5.81 3458.7 - 4.26E+06 - - - -1.9018 - 1.431 0.323 - 216.1 1 2 0 -0.0017 8 0 0 0 2.19E+08 1.49E+08 - - - 2.507 0.9999 221125_WJC_METTL3_EV_vs_WT_F01.17621.17621.2 2.20E-05 16-Nov R.LSMMLLDSR[166.11].A "sp|Q9H6R4|NOL6_HUMAN,tr|A0A0A0MRW6|A0A0A0MRW6_HUMAN" 2 1074.5441 0.78 5414 17621 2 1074.543335 538.2793 Nucleolar protein 6 OS=Homo sapiens OX=9606 GN=NOL6 PE=1 SV=2 5.84 3459.1 - 735200 - - - -0.7184 - 2.203 0.494 - 417.6 1 2 0 -0.0008 9 0 0 0 2.57E+07 3.30E+07 - - - 4.9744 0.9997 221125_WJC_METTL3_EV_vs_WT_F01.17626.17626.2 6.95E-05 20-Sep R.AVVPSYIPLVK[136.11].K sp|P36551|HEM6_HUMAN 1 1192.7311 1.14 5417 17626 2 1192.730063 597.3728 "Oxygen-dependent coproporphyrinogen-III oxidase, mitochondrial OS=Homo sapiens OX=9606 GN=CPOX PE=1 SV=3" 8.63 3459.7 - 9.56E+06 - - - -0.8661 - 1.833 0.41 - 297.4 1 2 0 -0.001 11 0 0 0 2.05E+08 1.80E+08 - - - 3.7082 0.9097 221125_WJC_METTL3_EV_vs_WT_F01.17627.17627.2 0.899 12-Jun H.ILLWDTR[166.11].N "sp|Q9BTV6|DPH7_HUMAN,sp|Q9BQA1|MEP50_HUMAN,tr|H0Y711|H0Y711_HUMAN" 3 925.5261 2.47 5418 17627 2 925.525327 463.7703 Diphthine methyltransferase OS=Homo sapiens OX=9606 GN=DPH7 PE=1 SV=2 5.84 3459.8 - 6.56E+06 - - - -0.8049 - 1.374 0.269 - 142.7 1 1 0 -0.0007 7 0 0 0 1.54E+09 6.26E+08 - - - 2.0343 0.9998 221125_WJC_METTL3_EV_vs_WT_F01.17628.17628.2 0.00013 16-Sep R.LSMMLLDSR.A "sp|Q9H6R4|NOL6_HUMAN,tr|A0A0A0MRW6|A0A0A0MRW6_HUMAN" 2 1064.5358 0.78 5419 17628 2 1064.535412 533.2752 Nucleolar protein 6 OS=Homo sapiens OX=9606 GN=NOL6 PE=1 SV=2 5.84 3459.9 - 976761 - - - -0.3992 - 1.913 0.402 - 280.1 1 2 0 -0.0004 9 0 0 0 2.57E+07 3.30E+07 - - - 3.8867 0.9995 221125_WJC_METTL3_EV_vs_WT_F01.17630.17630.2 0.00163 16-Jul R.LGIQLDFEK[136.11].N "sp|Q14683|SMC1A_HUMAN,tr|G8JLG1|G8JLG1_HUMAN,tr|A0A6Q8PHC3|A0A6Q8PHC3_HUMAN" 3 1069.5899 1.25 5421 17630 2 1069.590218 535.8022 Structural maintenance of chromosomes protein 1A OS=Homo sapiens OX=9606 GN=SMC1A PE=1 SV=2 4.37 3460 - 704520 - - - 0.287 - 1.562 0.377 - 89.3 1 2 0 0.0003 9 0 0 0 5.10E+07 4.07E+07 - - - 3.1156 0.9998 221125_WJC_METTL3_EV_vs_WT_F01.17633.17633.2 2.99E-05 18-Sep R.MMGLEVLGEK.K sp|Q08J23|NSUN2_HUMAN 1 1105.5512 1 5423 17633 2 1105.549896 553.7829 RNA cytosine C(5)-methyltransferase NSUN2 OS=Homo sapiens OX=9606 GN=NSUN2 PE=1 SV=2 4.53 3460.5 - 1.97E+06 - - - -1.137 - 1.83 0.501 - 200.2 1 2 0 -0.0013 10 0 0 0 3.93E+07 3.93E+07 - - - 4.4278 0.9997 221125_WJC_METTL3_EV_vs_WT_F01.17635.17635.2 3.55E-05 20-Jul R.AVVPSYIPLVK.K sp|P36551|HEM6_HUMAN 1 1184.7169 1.14 5424 17635 2 1184.715888 593.3657 "Oxygen-dependent coproporphyrinogen-III oxidase, mitochondrial OS=Homo sapiens OX=9606 GN=CPOX PE=1 SV=3" 8.63 3460.7 - 1.13E+07 - - - -0.8508 - 1.746 0.455 - 171.6 1 2 0 -0.001 11 0 0 0 2.05E+08 1.80E+08 - - - 3.909 0.9996 221125_WJC_METTL3_EV_vs_WT_F01.17637.17637.2 0.000909 20-Nov R.IVLLDSSLEYK[136.11].K "sp|P49368|TCPG_HUMAN,tr|B4DUR8|B4DUR8_HUMAN,tr|Q5SZX6|Q5SZX6_HUMAN" 3 1286.7213 0.26 5426 17637 2 1286.719433 644.3679 T-complex protein 1 subunit gamma OS=Homo sapiens OX=9606 GN=CCT3 PE=1 SV=4 4.37 3460.8 - 1.37E+06 - - - -1.4657 - 2.064 0.368 - 283.2 1 2 0 -0.0019 11 0 0 0 1.14E+07 4.43E+07 - - - 3.7188 0.983 221125_WJC_METTL3_EV_vs_WT_F01.17639.17639.2 0.296 16-Aug K.LQGILADLR.D "sp|Q9NRL3|STRN4_HUMAN,tr|F5GYK2|F5GYK2_HUMAN,tr|R4GN16|R4GN16_HUMAN" 3 997.592 2.57 5428 17639 2 997.58861 499.8033 Striatin-4 OS=Homo sapiens OX=9606 GN=STRN4 PE=1 SV=2 5.84 3461 - 562053 - - - -3.4283 - 1.682 0.133 - 171.9 1 2 0 -0.0034 9 0 0 0 2.33E+07 9.05E+06 - - - 1.5266 0.9999 221125_WJC_METTL3_EV_vs_WT_F01.17648.17648.2 3.97E-05 13/24 K.VLATTFDPYLGGR.N "sp|O95757|HS74L_HUMAN,tr|D6RJ96|D6RJ96_HUMAN,tr|E9PDE8|E9PDE8_HUMAN" 3 1408.7351 0.15 5435 17648 2 1408.735012 705.3748 Heat shock 70 kDa protein 4L OS=Homo sapiens OX=9606 GN=HSPA4L PE=1 SV=3 5.81 3462.2 - 1.39E+06 - - - -0.0376 - 2.565 0.53 - 424.9 1 2 0 -0.0001 13 0 0 0 3.01E+07 2.07E+08 - - - 5.3731 0.9502 221125_WJC_METTL3_EV_vs_WT_F01.17650.17650.2 0.0954 12-May R.LVVLPFR[166.11].R sp|Q10570|CPSF1_HUMAN 1 852.5461 3.85 5437 17650 2 852.545084 427.2803 Cleavage and polyadenylation specificity factor subunit 1 OS=Homo sapiens OX=9606 GN=CPSF1 PE=1 SV=2 9.75 3462.4 - 457507 - - - -1.1671 - 1.12 0.044 - 74.5 1 2 0 -0.001 7 0 0 0 3.02E+07 7.84E+06 - - - -0.2752 0.9942 221125_WJC_METTL3_EV_vs_WT_F01.17655.17655.2 0.828 12-Oct R.LLDFLQK[136.11].R "sp|Q8NEM7|SP20H_HUMAN,tr|B4E2D5|B4E2D5_HUMAN,tr|R4GND2|R4GND2_HUMAN,tr|F6S7C4|F6S7C4_HUMAN" 4 883.5259 1.15 5440 17655 2 883.52515 442.7702 Transcription factor SPT20 homolog OS=Homo sapiens OX=9606 GN=SUPT20H PE=1 SV=2 5.84 3463.1 - 7.18E+06 - - - -0.7968 - 1.712 0.044 - 242.1 1 2 0 -0.0007 7 0 0 0 1.34E+08 1.17E+08 - - - 1.0694 0.9996 221125_WJC_METTL3_EV_vs_WT_F01.17656.17656.2 0.0128 16-Sep K.LFLVQLQEK[136.11].A "sp|O43809|CPSF5_HUMAN,tr|H3BND3|H3BND3_HUMAN" 2 1124.6685 0.96 5441 17656 2 1124.667562 563.3415 Cleavage and polyadenylation specificity factor subunit 5 OS=Homo sapiens OX=9606 GN=NUDT21 PE=1 SV=1 6 3463.1 - 917264 - - - -0.8305 - 1.868 0.343 - 218.4 1 2 0 -0.0009 9 0 0 0 4.20E+07 4.36E+07 - - - 3.3819 0.9985 221125_WJC_METTL3_EV_vs_WT_F01.17660.17660.2 7.37E-05 22-Sep R.FLPSYQAVEYMR.R "sp|P20933|ASPG_HUMAN,tr|H0Y9C7|H0Y9C7_HUMAN" 2 1502.7228 18.63 5443 17660 2 1502.717331 752.3687 N(4)-(beta-N-acetylglucosaminyl)-L-asparaginase OS=Homo sapiens OX=9606 GN=AGA PE=1 SV=2 6 3463.7 - 494498 - - - -3.6301 - 1.611 0.498 - 183.4 1 2 0 -0.0055 12 0 0 0 9.02E+06 4.84E+05 - - - 3.9722 0.9255 221125_WJC_METTL3_EV_vs_WT_F01.17661.17661.2 4.58 18-Jun K.TIFLLTNPMK.L sp|Q0VAA2|LR74A_HUMAN 1 1176.6577 26.23 5444 17661 2 1176.654918 589.3361 Leucine-rich repeat-containing protein 74A OS=Homo sapiens OX=9606 GN=LRRC74A PE=2 SV=2 8.41 3463.8 - 330648 - - - -2.3363 - 1.17 0.061 - 119.8 1 2 0 -0.0027 10 0 0 0 7.02E+06 2.68E+05 - - - -0.0711 0.9996 221125_WJC_METTL3_EV_vs_WT_F01.17662.17662.2 0.00152 14-Sep K.LDYILGLK[136.11].L "sp|P46781|RS9_HUMAN,tr|C9JM19|C9JM19_HUMAN,tr|B5MCT8|B5MCT8_HUMAN" 3 941.5677 0.85 5445 17662 2 941.5677 471.7911 40S ribosomal protein S9 OS=Homo sapiens OX=9606 GN=RPS9 PE=1 SV=3 5.83 3463.9 - 1.85E+06 - - - -0.0202 - 1.92 0.293 - 247.2 1 2 0 0 8 0 0 0 1.65E+08 1.94E+08 - - - 3.1725 0.9995 221125_WJC_METTL3_EV_vs_WT_F01.17671.17671.2 0.00882 14-Sep K.LDYILGLK.L "sp|P46781|RS9_HUMAN,tr|C9JM19|C9JM19_HUMAN,tr|B5MCT8|B5MCT8_HUMAN" 3 933.5535 0.84 5452 17671 2 933.553185 467.784 40S ribosomal protein S9 OS=Homo sapiens OX=9606 GN=RPS9 PE=1 SV=3 5.83 3464.9 - 2.47E+06 - - - -0.3578 - 1.893 0.289 - 243.9 1 2 0 -0.0003 8 0 0 0 1.65E+08 1.96E+08 - - - 3.1001 0.9996 221125_WJC_METTL3_EV_vs_WT_F01.17672.17672.2 0.0957 16-Oct K.LFLVQLQEK.A "sp|O43809|CPSF5_HUMAN,tr|H3BND3|H3BND3_HUMAN" 2 1116.6543 0.89 5453 17672 2 1116.654246 559.3344 Cleavage and polyadenylation specificity factor subunit 5 OS=Homo sapiens OX=9606 GN=NUDT21 PE=1 SV=1 6 3465 - 1.78E+06 - - - -0.0448 - 1.836 0.325 - 353.4 1 2 0 -0.0001 9 0 0 0 4.59E+07 5.18E+07 - - - 3.1992 0.9937 221125_WJC_METTL3_EV_vs_WT_F01.17675.17675.2 0.0618 16-Aug K.YFELEPLAR.G "sp|Q9NXU5|ARL15_HUMAN,tr|A0A087WUW9|A0A087WUW9_HUMAN" 2 1136.5866 0.72 5456 17675 2 1136.583114 569.3006 ADP-ribosylation factor-like protein 15 OS=Homo sapiens OX=9606 GN=ARL15 PE=1 SV=1 4.53 3465.3 - 371023 - - - -3.0759 - 1.442 0.273 - 153.5 1 2 0 -0.0035 9 0 0 0 4.20E+06 5.86E+06 - - - 2.1152 0.9949 221125_WJC_METTL3_EV_vs_WT_F01.17680.17680.2 0.181 12-Jun R.AVFWDIK[136.11].N sp|Q6P2Q9|PRP8_HUMAN 1 885.484 0.81 5459 17680 2 885.483453 443.7493 Pre-mRNA-processing-splicing factor 8 OS=Homo sapiens OX=9606 GN=PRPF8 PE=1 SV=2 5.88 3465.8 - 4.19E+06 - - - -0.6064 - 1.331 0.159 - 119.2 1 2 0 -0.0005 7 0 0 0 7.91E+07 9.78E+07 - - - 1.1212 0.9997 221125_WJC_METTL3_EV_vs_WT_F01.17681.17681.2 0.00691 16-Sep R.YLTVATVFR[166.11].G "sp|Q13509|TBB3_HUMAN,sp|Q9BUF5|TBB6_HUMAN,tr|A0A0B4J269|A0A0B4J269_HUMAN,tr|K7ESM5|K7ESM5_HUMAN" 4 1078.6051 1.34 5460 17681 2 1078.604962 540.3098 Tubulin beta-3 chain OS=Homo sapiens OX=9606 GN=TUBB3 PE=1 SV=2 8.75 3465.8 - 2.21E+06 - - - -0.0825 - 1.858 0.37 - 270.4 1 2 0 -0.0001 9 0 0 0 5.86E+07 4.37E+07 - - - 3.566 0.9998 221125_WJC_METTL3_EV_vs_WT_F01.17682.17682.2 0.000526 20-Sep K.VLTPELYAELR[166.11].A "sp|P12277|KCRB_HUMAN,tr|G3V461|G3V461_HUMAN,tr|G3V4N7|G3V4N7_HUMAN" 3 1312.7266 0.88 5461 17682 2 1312.726115 657.3706 Creatine kinase B-type OS=Homo sapiens OX=9606 GN=CKB PE=1 SV=1 4.53 3465.9 - 1.95E+06 - - - -0.387 - 2.097 0.426 - 307.6 1 2 0 -0.0005 11 0 0 0 1.01E+08 1.14E+08 - - - 4.1905 0.9994 221125_WJC_METTL3_EV_vs_WT_F01.17683.17683.2 2.09E-05 16-Aug R.YDLTVPFAR[166.11].Y "sp|P49590|SYHM_HUMAN,sp|P12081|HARS1_HUMAN,tr|A0A6Q8PF47|A0A6Q8PF47_HUMAN,tr|A0A2R8Y5P7|A0A2R8Y5P7_HUMAN,tr|A0A6Q8PF07|A0A6Q8PF07_HUMAN,tr|A0A2R8Y5E8|A0A2R8Y5E8_HUMAN,tr|A0A2R8Y6I1|A0A2R8Y6I1_HUMAN,tr|A0A6Q8PHA5|A0A6Q8PHA5_HUMAN,tr|E7ETE2|E7ETE2_HUMAN,tr|A0A2R8Y3N3|A0A2R8Y3N3_HUMAN,tr|A0A6Q8PFF2|A0A6Q8PFF2_HUMAN,tr|A0A2R8Y4X6|A0A2R8Y4X6_HUMAN,tr|A0A6Q8PFG9|A0A6Q8PFG9_HUMAN,tr|D6RJE6|D6RJE6_HUMAN,tr|A0A6Q8PFN6|A0A6Q8PFN6_HUMAN" 15 1090.5687 0.66 5462 17683 2 1090.568634 546.2916 "Histidine--tRNA ligase, mitochondrial OS=Homo sapiens OX=9606 GN=HARS2 PE=1 SV=1" 5.84 3466 - 1.19E+06 - - - -0.0284 - 1.7 0.3 - 231.8 1 2 0 0 9 0 0 0 1.17E+07 1.77E+07 - - - 2.7919 0.9852 221125_WJC_METTL3_EV_vs_WT_F01.17684.17684.2 0.0109 20-Nov R.SALLVQLATAR.P "sp|Q9BSV6|SEN34_HUMAN,tr|A0A590UJ73|A0A590UJ73_HUMAN,tr|E7EQB3|E7EQB3_HUMAN,tr|A0A0G2JNK5|A0A0G2JNK5_HUMAN,tr|A0A0G2JNL0|A0A0G2JNL0_HUMAN,tr|A0A590UJW4|A0A590UJW4_HUMAN,tr|B0V3J0|B0V3J0_HUMAN" 7 1141.6819 1.98 5463 17684 2 1141.682661 571.8482 tRNA-splicing endonuclease subunit Sen34 OS=Homo sapiens OX=9606 GN=TSEN34 PE=1 SV=1 9.47 3466.1 - 754049 - - - 0.6596 - 2.159 0.385 - 352.9 1 1 0 0.0008 11 0 0 0 5.45E+07 2.76E+07 - - - 3.9664 0.9995 221125_WJC_METTL3_EV_vs_WT_F01.17690.17690.3 0.00184 Sep-36 R.IC[160.03]DDELILIK.N "sp|P17987|TCPA_HUMAN,tr|F5GZ03|F5GZ03_HUMAN,tr|F5H282|F5H282_HUMAN,tr|E7EQR6|E7EQR6_HUMAN,tr|E7ERF2|E7ERF2_HUMAN" 5 1230.653 0.56 5467 17690 3 1230.651826 411.2249 T-complex protein 1 subunit alpha OS=Homo sapiens OX=9606 GN=TCP1 PE=1 SV=1 4.03 3466.8 - 707400 - - - -0.9345 - 1.594 0.346 - 97 1 2 0 -0.0011 10 0 0 0 1.06E+07 1.90E+07 - - - 3.7589 0.9998 221125_WJC_METTL3_EV_vs_WT_F01.17691.17691.2 1.55E-05 22-Oct K.LFVTNDAATILR[166.11].E "sp|P50990|TCPQ_HUMAN,tr|H7C4C8|H7C4C8_HUMAN" 2 1342.7484 0.37 5468 17691 2 1342.74727 672.3815 T-complex protein 1 subunit theta OS=Homo sapiens OX=9606 GN=CCT8 PE=1 SV=4 5.84 3466.9 - 686413 - - - -0.8572 - 2.084 0.41 - 290.1 1 2 0 -0.0012 12 0 0 0 9.37E+08 2.51E+09 - - - 4.0009 0.9074 221125_WJC_METTL3_EV_vs_WT_F01.17692.17692.2 0.158 18-Aug G.AGALQVVGLK[136.11].T sp|Q9P1Q0|VPS54_HUMAN 1 962.6004 1.21 5469 17692 2 962.601588 482.3075 Vacuolar protein sorting-associated protein 54 OS=Homo sapiens OX=9606 GN=VPS54 PE=1 SV=2 8.8 3467.1 - 410122 - - - 1.2175 - 1.527 0.274 - 121.7 1 1 0 0.0012 10 0 0 0 2.75E+08 2.27E+08 - - - 2.246 0.9958 221125_WJC_METTL3_EV_vs_WT_F01.17694.17694.3 0.014 Aug-40 K.VLTPELYAELR.A "sp|P12277|KCRB_HUMAN,tr|G3V461|G3V461_HUMAN,tr|G3V4N7|G3V4N7_HUMAN" 3 1302.7184 0.55 5471 17694 3 1302.720843 435.2467 Creatine kinase B-type OS=Homo sapiens OX=9606 GN=CKB PE=1 SV=1 4.53 3467.3 - 255809 - - - 1.9114 - 1.762 0.232 - 80.3 1 2 0 0.0025 11 0 0 0 4.04E+06 7.40E+06 - - - 2.7351 0.9997 221125_WJC_METTL3_EV_vs_WT_F01.17697.17697.2 0.00121 16-Sep R.YLDVSILGK[136.11].F sp|Q86U44|MTA70_HUMAN 1 1014.5841 0.08 5472 17697 2 1014.582888 508.2993 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 5.83 3467.7 - 1.29E+07 - - - -1.1926 - 1.766 0.448 - 188.6 1 2 0 -0.0012 9 0 0 0 6.38E+07 8.05E+08 - - - 3.9949 0.9997 221125_WJC_METTL3_EV_vs_WT_F01.17698.17698.2 0.000414 16-Jul K.VLEALQVLR[166.11].C "sp|Q9H7D7|WDR26_HUMAN,tr|A0A7P0SXD0|A0A7P0SXD0_HUMAN,tr|A0A7I2YQL3|A0A7I2YQL3_HUMAN,tr|C9JCS7|C9JCS7_HUMAN,tr|A0A7I2YQQ9|A0A7I2YQQ9_HUMAN,tr|A0A499FIZ0|A0A499FIZ0_HUMAN" 6 1049.6472 0.76 5473 17698 2 1049.646414 525.8309 WD repeat-containing protein 26 OS=Homo sapiens OX=9606 GN=WDR26 PE=1 SV=3 5.97 3467.8 - 1.30E+06 - - - -0.7965 - 1.877 0.396 - 129 1 2 0 -0.0008 9 0 0 0 1.29E+07 1.71E+07 - - - 3.7873 0.997 221125_WJC_METTL3_EV_vs_WT_F01.17702.17702.2 3.52E-05 16-Sep K.SPLQSVVVR.R "sp|Q9Y2W1|TR150_HUMAN,tr|A0A3B3ITZ9|A0A3B3ITZ9_HUMAN" 2 983.5764 2.11 5477 17702 2 983.581213 492.7955 Thyroid hormone receptor-associated protein 3 OS=Homo sapiens OX=9606 GN=THRAP3 PE=1 SV=2 9.47 3468.1 - 933998 - - - 4.9137 - 1.977 0.456 - 254.5 1 2 0 0.0048 9 0 0 0 1.70E+07 8.06E+06 - - - 4.3793 0.9997 221125_WJC_METTL3_EV_vs_WT_F01.17703.17703.2 0.13 22-Oct R.LLQTIAVLEAQR.S sp|Q8IYH5|ZZZ3_HUMAN 1 1353.798 2 5478 17703 2 1353.79724 677.9063 ZZ-type zinc finger-containing protein 3 OS=Homo sapiens OX=9606 GN=ZZZ3 PE=1 SV=1 6 3468.2 - 629382 - - - -0.5614 - 2.32 0.349 - 380.8 1 2 0 -0.0008 12 0 0 0 1.14E+07 5.70E+06 - - - 3.8328 0.9998 221125_WJC_METTL3_EV_vs_WT_F01.17704.17704.2 0.000426 22-Dec K.LFVTNDAATILR.E "sp|P50990|TCPQ_HUMAN,tr|H7C4C8|H7C4C8_HUMAN" 2 1332.7402 0.37 5479 17704 2 1332.737525 667.3774 T-complex protein 1 subunit theta OS=Homo sapiens OX=9606 GN=CCT8 PE=1 SV=4 5.84 3468.3 - 588965 - - - -1.9704 - 2.415 0.52 - 553.2 1 2 0 -0.0026 12 0 0 0 9.37E+08 2.51E+09 - - - 5.2008 0.9997 221125_WJC_METTL3_EV_vs_WT_F01.17710.17710.2 0.0159 28-Oct R.IITGPAPVLPPAALR[166.11].T "sp|Q96PU8|QKI_HUMAN,tr|H0YG47|H0YG47_HUMAN,tr|H0YGD6|H0YGD6_HUMAN" 3 1494.9162 2.89 5484 17710 2 1494.914359 748.4654 Protein quaking OS=Homo sapiens OX=9606 GN=QKI PE=1 SV=1 9.75 3469.1 - 476534 - - - -1.2014 - 1.996 0.42 - 225.9 1 2 0 -0.0018 15 0 0 0 3.28E+07 1.13E+07 - - - 3.8418 0.9862 221125_WJC_METTL3_EV_vs_WT_F01.17712.17712.2 0.118 20-Nov R.SALLVQLATAR[166.11].P "sp|Q9BSV6|SEN34_HUMAN,tr|A0A590UJ73|A0A590UJ73_HUMAN,tr|E7EQB3|E7EQB3_HUMAN,tr|A0A0G2JNK5|A0A0G2JNK5_HUMAN,tr|A0A0G2JNL0|A0A0G2JNL0_HUMAN,tr|A0A590UJW4|A0A590UJW4_HUMAN,tr|B0V3J0|B0V3J0_HUMAN" 7 1151.6902 1.97 5486 17712 2 1151.69003 576.8524 tRNA-splicing endonuclease subunit Sen34 OS=Homo sapiens OX=9606 GN=TSEN34 PE=1 SV=1 9.47 3469.3 - 1.51E+06 - - - -0.1285 - 2.385 0.336 - 285.9 1 1 0 -0.0001 11 0 0 0 5.45E+07 2.77E+07 - - - 3.874 0.8269 221125_WJC_METTL3_EV_vs_WT_F01.17713.17713.2 0.899 Apr-32 R.ASSGGGAGGAAGYAPVK[136.11].Y sp|P25067|CO8A2_HUMAN 1 1384.6826 0.88 5487 17713 2 1384.678508 693.3486 Collagen alpha-2(VIII) chain OS=Homo sapiens OX=9606 GN=COL8A2 PE=1 SV=2 8.63 3469.4 - 1.44E+06 - - - -2.9855 - 1.031 0.174 - 20 53 2 0 -0.0041 17 0 0 0 1.27E+08 1.45E+08 - - - -0.3703 0.9978 221125_WJC_METTL3_EV_vs_WT_F01.17714.17714.2 0.000314 20-Oct R.LLESSLISLSR.Y sp|Q9C0C7|AMRA1_HUMAN 1 1216.7027 0.49 5488 17714 2 1216.70771 609.3586 Activating molecule in BECN1-regulated autophagy protein 1 OS=Homo sapiens OX=9606 GN=AMBRA1 PE=1 SV=2 6 3469.5 - 683572 - - - 4.1152 - 1.907 0.44 - 216.4 1 2 0 0.005 11 0 0 0 3.16E+07 6.45E+07 - - - 4.0356 0.9998 221125_WJC_METTL3_EV_vs_WT_F01.17718.17718.2 0.0156 13/22 R.LLQTIAVLEAQR[166.11].S sp|Q8IYH5|ZZZ3_HUMAN 1 1363.8063 2 5492 17718 2 1363.806658 682.9104 ZZ-type zinc finger-containing protein 3 OS=Homo sapiens OX=9606 GN=ZZZ3 PE=1 SV=1 6 3470 - 360697 - - - 0.2845 - 2.608 0.372 - 771.9 1 2 0 0.0004 12 0 0 0 1.14E+07 5.70E+06 - - - 4.3107 0.9939 221125_WJC_METTL3_EV_vs_WT_F01.17724.17724.2 0.000145 16-Oct R.PLVETIFER[166.11].G "sp|O00139|KIF2A_HUMAN,tr|D6R9M0|D6R9M0_HUMAN,tr|A0A6Q8PFA6|A0A6Q8PFA6_HUMAN,tr|A0A6Q8PGG1|A0A6Q8PGG1_HUMAN,tr|A0A6Q8PGH7|A0A6Q8PGH7_HUMAN,tr|A0A6Q8PG37|A0A6Q8PG37_HUMAN,tr|A0A6Q8PH57|A0A6Q8PH57_HUMAN" 7 1112.6105 1.17 5496 17724 2 1112.610206 557.3125 Kinesin-like protein KIF2A OS=Homo sapiens OX=9606 GN=KIF2A PE=1 SV=3 4.53 3470.8 - 2.12E+06 - - - -0.2912 - 2.216 0.52 - 431.8 1 1 0 -0.0003 9 0 0 0 4.15E+07 3.54E+07 - - - 5.1836 0.9997 221125_WJC_METTL3_EV_vs_WT_F01.17726.17726.2 0.0617 14-Sep R.SSLLLGFR[166.11].R "sp|P42704|LPPRC_HUMAN,tr|A0A804HI14|A0A804HI14_HUMAN,tr|A0A804HL40|A0A804HL40_HUMAN,tr|A0A804HKJ0|A0A804HKJ0_HUMAN,tr|A0A804HKR3|A0A804HKR3_HUMAN,tr|A0A804HIN4|A0A804HIN4_HUMAN,tr|A0A804HLG8|A0A804HLG8_HUMAN,tr|A0A804HIV5|A0A804HIV5_HUMAN,tr|A0A804HHY9|A0A804HHY9_HUMAN,tr|A0A804HJH8|A0A804HJH8_HUMAN,tr|B8ZZ38|B8ZZ38_HUMAN,tr|A0A804HI40|A0A804HI40_HUMAN,tr|A0A804HJZ1|A0A804HJZ1_HUMAN,tr|C9JCA9|C9JCA9_HUMAN,tr|A0A804HIQ7|A0A804HIQ7_HUMAN,tr|A0A804HK30|A0A804HK30_HUMAN,tr|A0A804HKI2|A0A804HKI2_HUMAN,tr|A0A804HJI0|A0A804HJI0_HUMAN,tr|A0A804HIG4|A0A804HIG4_HUMAN,tr|A0A804HK02|A0A804HK02_HUMAN" 20 901.5261 0.69 5498 17726 2 901.526002 451.7703 "Leucine-rich PPR motif-containing protein, mitochondrial OS=Homo sapiens OX=9606 GN=LRPPRC PE=1 SV=3" 9.47 3470.9 - 1.91E+06 - - - -0.0776 - 1.848 0.339 - 296.6 1 2 0 -0.0001 8 0 0 0 5.22E+07 7.56E+07 - - - 3.3969 0.9985 221125_WJC_METTL3_EV_vs_WT_F01.17731.17731.2 0.0105 18-Aug R.VLAMLVQEMK[136.11].S sp|O15047|SET1A_HUMAN 1 1168.6439 0.97 5503 17731 2 1168.646072 585.3292 Histone-lysine N-methyltransferase SETD1A OS=Homo sapiens OX=9606 GN=SETD1A PE=1 SV=3 5.97 3471.5 - 405006 - - - 1.8269 - 1.612 0.313 - 128.9 1 2 0 0.0021 10 0 0 0 5.59E+06 5.76E+06 - - - 2.6849 1 221125_WJC_METTL3_EV_vs_WT_F01.17732.17732.2 0.000431 14/26 K.LLDVTGGLGTDELR[166.11].L "sp|Q9Y4W2|LAS1L_HUMAN,tr|A0A7I2V3R6|A0A7I2V3R6_HUMAN,tr|A0A7I2V3Q3|A0A7I2V3Q3_HUMAN,tr|A0A7I2V4V0|A0A7I2V4V0_HUMAN,tr|A0A7I2V5R7|A0A7I2V5R7_HUMAN,tr|A0A7I2V653|A0A7I2V653_HUMAN,tr|A0A7I2YQI7|A0A7I2YQI7_HUMAN" 7 1467.7808 1.16 5504 17732 2 1467.778219 734.8977 Ribosomal biogenesis protein LAS1L OS=Homo sapiens OX=9606 GN=LAS1L PE=1 SV=2 4.03 3471.6 - 353129 - - - -1.7877 - 2.938 0.551 - 804.4 1 2 0 -0.0026 14 0 0 0 5.22E+06 4.49E+06 - - - 5.8144 0.9999 221125_WJC_METTL3_EV_vs_WT_F01.17735.17735.2 9.42E-05 18-Nov R.IC[160.03]DDELILIK[136.11].N "sp|P17987|TCPA_HUMAN,tr|F5GZ03|F5GZ03_HUMAN,tr|F5H282|F5H282_HUMAN,tr|E7EQR6|E7EQR6_HUMAN,tr|E7ERF2|E7ERF2_HUMAN" 5 1238.6672 0.46 5506 17735 2 1238.667014 620.3409 T-complex protein 1 subunit alpha OS=Homo sapiens OX=9606 GN=TCP1 PE=1 SV=1 4.03 3472 - 1.55E+07 - - - -0.1308 - 2.676 0.45 - 288.7 1 2 0 -0.0002 10 0 0 0 7.97E+08 1.71E+09 - - - 5.1122 0.9994 221125_WJC_METTL3_EV_vs_WT_F01.17738.17738.2 0.0934 16-Nov R.VSVGLLLVK.S "sp|Q96DA0|ZG16B_HUMAN,tr|I3L1H9|I3L1H9_HUMAN,tr|A0A0C4DGN4|A0A0C4DGN4_HUMAN,tr|I3L3X0|I3L3X0_HUMAN" 4 926.6165 999 5508 17738 2 926.616479 464.3155 Zymogen granule protein 16 homolog B OS=Homo sapiens OX=9606 GN=ZG16B PE=1 SV=3 8.72 3472.3 - 4.16E+06 - - - 0.027 - 1.753 0.304 - 342.5 1 2 0 0 9 0 0 0 6.93E+07 0.00E+00 - - - 2.9103 1 221125_WJC_METTL3_EV_vs_WT_F01.17739.17739.3 4.27E-05 Dec-44 K.LFVTNDAATILR[166.11].E "sp|P50990|TCPQ_HUMAN,tr|H7C4C8|H7C4C8_HUMAN" 2 1342.7484 0.44 5509 17739 3 1342.748594 448.5901 T-complex protein 1 subunit theta OS=Homo sapiens OX=9606 GN=CCT8 PE=1 SV=4 5.84 3472.3 - 3.72E+06 - - - 0.1288 - 2.136 0.507 - 241.7 1 2 0 0.0002 12 0 0 0 5.14E+07 1.18E+08 - - - 6.2962 0.9998 221125_WJC_METTL3_EV_vs_WT_F01.17740.17740.2 0.000119 18-Sep K.YLAIAPPIIK[136.11].Q "sp|Q16531|DDB1_HUMAN,tr|F5GWI0|F5GWI0_HUMAN,tr|A0A7P0TAK7|A0A7P0TAK7_HUMAN,tr|A0A7P0T870|A0A7P0T870_HUMAN,tr|A0A7P0TB30|A0A7P0TB30_HUMAN,tr|F5GY55|F5GY55_HUMAN,tr|A0A7P0Z4B9|A0A7P0Z4B9_HUMAN,tr|A0A7P0T965|A0A7P0T965_HUMAN" 8 1105.6991 0.67 5510 17740 2 1105.699122 553.8568 DNA damage-binding protein 1 OS=Homo sapiens OX=9606 GN=DDB1 PE=1 SV=1 8.59 3472.4 - 2.42E+06 - - - 0.0488 - 1.77 0.478 - 257.2 1 2 0 0.0001 10 0 0 0 7.31E+07 1.09E+08 - - - 4.1653 0.9759 221125_WJC_METTL3_EV_vs_WT_F01.17741.17741.2 0.00413 18-Aug A.MVWEGLNVVK.T "sp|O60361|NDK8_HUMAN,sp|P15531|NDKA_HUMAN,sp|P22392|NDKB_HUMAN,tr|Q32Q12|Q32Q12_HUMAN,tr|Q32Q12|Q32Q12_HUMAN,tr|J3KPD9|J3KPD9_HUMAN,tr|E7ERL0|E7ERL0_HUMAN" 7 1173.6216 1.37 5511 17741 2 1173.621184 587.8181 Putative nucleoside diphosphate kinase OS=Homo sapiens OX=9606 GN=NME2P1 PE=5 SV=1 5.75 3472.4 - 1.43E+06 - - - -0.3681 - 1.642 0.38 - 153.2 1 1 0 -0.0004 10 0 0 0 4.54E+07 3.32E+07 - - - 3.2318 0.9985 221125_WJC_METTL3_EV_vs_WT_F01.17742.17742.2 0.152 12-Jun R.AVFWDIK.N sp|Q6P2Q9|PRP8_HUMAN 1 877.4698 0.81 5512 17742 2 877.470157 439.7422 Pre-mRNA-processing-splicing factor 8 OS=Homo sapiens OX=9606 GN=PRPF8 PE=1 SV=2 5.88 3472.5 - 1.41E+06 - - - 0.4182 - 1.335 0.289 - 147.9 1 2 0 0.0004 7 0 0 0 7.89E+07 9.73E+07 - - - 2.0909 0.9995 221125_WJC_METTL3_EV_vs_WT_F01.17745.17745.2 0.0223 22-Oct K.WELLQQVDTSTR.T sp|P04264|K2C1_HUMAN 1 1474.7416 92.32 5515 17745 2 1474.743043 738.3781 "Keratin, type II cytoskeletal 1 OS=Homo sapiens OX=9606 GN=KRT1 PE=1 SV=6" 4.37 3472.9 - 369344 - - - 0.9737 - 1.971 0.345 - 304 1 2 0 0.0014 12 0 0 0 8.57E+06 9.28E+04 - - - 3.3741 1 221125_WJC_METTL3_EV_vs_WT_F01.17749.17749.2 1.96E-09 13/20 R.FPC[160.03]VVYINEVR[166.11].V sp|Q69YN4|VIR_HUMAN 1 1404.7099 1.06 5518 17749 2 1404.705709 703.3622 Protein virilizer homolog OS=Homo sapiens OX=9606 GN=VIRMA PE=1 SV=2 5.99 3473.3 - 590446 - - - -3.0028 - 2.463 0.609 - 645.3 1 2 0 -0.0042 11 0 0 0 6.81E+06 6.44E+06 - - - 5.9762 0.9993 221125_WJC_METTL3_EV_vs_WT_F01.17751.17751.2 0.000357 20-Jun K.LPVVISQC[160.03]GEM.- "sp|O43447|PPIH_HUMAN,tr|H0YEL5|H0YEL5_HUMAN,tr|A0A7I2YQS4|A0A7I2YQS4_HUMAN,tr|C9JQD4|C9JQD4_HUMAN" 4 1231.5941 - 5519 17751 2 1231.594898 616.8043 Peptidyl-prolyl cis-trans isomerase H OS=Homo sapiens OX=9606 GN=PPIH PE=1 SV=1 4 3473.5 - 8.26E+06 - - - 0.6642 - 1.293 0.421 - 140.1 1 2 0 0.0008 11 0 0 0 - - - - - 2.8454 0.9997 221125_WJC_METTL3_EV_vs_WT_F01.17752.17752.2 0.00666 18-Dec K.LAVNMVPFPR[166.11].L "sp|P04350|TBB4A_HUMAN,sp|Q9BVA1|TBB2B_HUMAN,sp|A6NNZ2|TBB8B_HUMAN,sp|P07437|TBB5_HUMAN,sp|Q13509|TBB3_HUMAN,sp|Q13885|TBB2A_HUMAN,sp|P68371|TBB4B_HUMAN,sp|Q9BUF5|TBB6_HUMAN,sp|Q3ZCM7|TBB8_HUMAN,sp|Q9H4B7|TBB1_HUMAN,tr|A0A0B4J269|A0A0B4J269_HUMAN,tr|Q5ST81|Q5ST81_HUMAN,tr|Q5JP53|Q5JP53_HUMAN,tr|K7ESM5|K7ESM5_HUMAN,tr|A0A075B736|A0A075B736_HUMAN,tr|Q5SQY0|Q5SQY0_HUMAN" 16 1152.6353 0.72 5520 17752 2 1152.635642 577.3249 Tubulin beta-4A chain OS=Homo sapiens OX=9606 GN=TUBB4A PE=1 SV=2 9.75 3473.6 - 5.20E+06 - - - 0.2924 - 2.144 0.326 - 645.6 1 2 0 0.0003 10 0 0 0 8.04E+08 1.12E+09 - - - 3.5776 0.9827 221125_WJC_METTL3_EV_vs_WT_F01.17753.17753.2 0.00738 18-Sep A.MVWEGLNVVK[136.11].T "sp|O60361|NDK8_HUMAN,sp|P15531|NDKA_HUMAN,sp|P22392|NDKB_HUMAN,tr|Q32Q12|Q32Q12_HUMAN,tr|Q32Q12|Q32Q12_HUMAN,tr|J3KPD9|J3KPD9_HUMAN,tr|E7ERL0|E7ERL0_HUMAN" 7 1181.6358 1.37 5521 17753 2 1181.636773 591.8252 Putative nucleoside diphosphate kinase OS=Homo sapiens OX=9606 GN=NME2P1 PE=5 SV=1 5.75 3473.6 - 2.27E+06 - - - 0.8099 - 1.93 0.401 - 230.8 1 1 0 0.001 10 0 0 0 4.54E+07 3.31E+07 - - - 3.8378 0.9994 221125_WJC_METTL3_EV_vs_WT_F01.17755.17755.2 0.00113 16-Jul K.LLQDFFNGK[136.11].E "sp|P54652|HSP72_HUMAN,sp|P11142|HSP7C_HUMAN,sp|P17066|HSP76_HUMAN,tr|E9PNE6|E9PNE6_HUMAN,tr|A8K7Q2|A8K7Q2_HUMAN,tr|E9PKE3|E9PKE3_HUMAN,tr|E9PN89|E9PN89_HUMAN" 7 1088.5746 0.33 5523 17755 2 1088.574605 545.2946 Heat shock-related 70 kDa protein 2 OS=Homo sapiens OX=9606 GN=HSPA2 PE=1 SV=1 5.84 3473.8 - 750329 - - - 0.0092 - 1.47 0.367 - 115.4 1 2 0 0 9 0 0 0 1.70E+07 5.08E+07 - - - 2.8662 0.9998 221125_WJC_METTL3_EV_vs_WT_F01.17760.17760.2 1.76E-05 20-Nov K.VLTPELYAELR.A "sp|P12277|KCRB_HUMAN,tr|G3V461|G3V461_HUMAN,tr|G3V4N7|G3V4N7_HUMAN" 3 1302.7184 0.88 5526 17760 2 1302.718355 652.3665 Creatine kinase B-type OS=Homo sapiens OX=9606 GN=CKB PE=1 SV=1 4.53 3474.5 - 4.07E+06 - - - 0.0015 - 2.411 0.361 - 513.8 1 2 0 0 11 0 0 0 1.01E+08 1.14E+08 - - - 4.0881 0.9992 221125_WJC_METTL3_EV_vs_WT_F01.17761.17761.2 0.007 18-Aug K.LAVNMVPFPR.L "sp|P04350|TBB4A_HUMAN,sp|Q9BVA1|TBB2B_HUMAN,sp|A6NNZ2|TBB8B_HUMAN,sp|P07437|TBB5_HUMAN,sp|Q13509|TBB3_HUMAN,sp|Q13885|TBB2A_HUMAN,sp|P68371|TBB4B_HUMAN,sp|Q9BUF5|TBB6_HUMAN,sp|Q3ZCM7|TBB8_HUMAN,sp|Q9H4B7|TBB1_HUMAN,tr|A0A0B4J269|A0A0B4J269_HUMAN,tr|Q5ST81|Q5ST81_HUMAN,tr|Q5JP53|Q5JP53_HUMAN,tr|K7ESM5|K7ESM5_HUMAN,tr|A0A075B736|A0A075B736_HUMAN,tr|Q5SQY0|Q5SQY0_HUMAN" 16 1142.627 0.72 5527 17761 2 1142.62658 572.3208 Tubulin beta-4A chain OS=Homo sapiens OX=9606 GN=TUBB4A PE=1 SV=2 9.75 3474.5 - 4.94E+06 - - - -0.3982 - 1.775 0.257 - 247.4 1 2 0 -0.0005 10 0 0 0 8.04E+08 1.12E+09 - - - 2.5407 0.9829 221125_WJC_METTL3_EV_vs_WT_F01.17772.17772.2 0.155 16-Aug R.EHALLAYTL.G "sp|Q05639|EF1A2_HUMAN,sp|P68104|EF1A1_HUMAN,sp|Q5VTE0|EF1A3_HUMAN,tr|A0A2R8Y488|A0A2R8Y488_HUMAN,tr|A0A7I2V659|A0A7I2V659_HUMAN,tr|A0A7I2V3H3|A0A7I2V3H3_HUMAN,tr|Q5JR01|Q5JR01_HUMAN,tr|A0A2U3TZH3|A0A2U3TZH3_HUMAN,tr|A0A7I2V5N4|A0A7I2V5N4_HUMAN,tr|A0A087WVQ9|A0A087WVQ9_HUMAN,tr|A0A087WV01|A0A087WV01_HUMAN,tr|A0A2R8Y660|A0A2R8Y660_HUMAN" 12 1029.5495 - 5536 17772 2 1029.548892 515.782 Elongation factor 1-alpha 2 OS=Homo sapiens OX=9606 GN=EEF1A2 PE=1 SV=1 5.24 3475.9 - 1.02E+07 - - - -0.5867 - 1.896 0.376 - 355.7 1 1 0 -0.0006 9 0 0 0 - - - - - 3.6688 0.9999 221125_WJC_METTL3_EV_vs_WT_F01.17774.17774.3 0.0043 Nov-44 K.LFVTNDAATILR.E "sp|P50990|TCPQ_HUMAN,tr|H7C4C8|H7C4C8_HUMAN" 2 1332.7402 0.42 5538 17774 3 1332.739289 445.254 T-complex protein 1 subunit theta OS=Homo sapiens OX=9606 GN=CCT8 PE=1 SV=4 5.84 3476 - 4.62E+06 - - - -0.6468 - 2.236 0.423 - 247.7 1 2 0 -0.0009 12 0 0 0 4.97E+07 1.18E+08 - - - 5.4863 0.9999 221125_WJC_METTL3_EV_vs_WT_F01.17775.17775.2 2.76E-06 16-Nov R.LIDFLEC[160.03]GK.T "sp|P17844|DDX5_HUMAN,tr|A0A7I2V5F5|A0A7I2V5F5_HUMAN,tr|J3KRZ1|J3KRZ1_HUMAN,tr|J3QSF1|J3QSF1_HUMAN,tr|A0A7I2V507|A0A7I2V507_HUMAN,tr|J3KTA4|J3KTA4_HUMAN,tr|A0A0G2JLI4|A0A0G2JLI4_HUMAN,tr|A0A7I2V2S0|A0A7I2V2S0_HUMAN" 8 1093.5478 0.85 5539 17775 2 1093.546982 547.7812 Probable ATP-dependent RNA helicase DDX5 OS=Homo sapiens OX=9606 GN=DDX5 PE=1 SV=1 4.37 3476.1 - 4.14E+06 - - - -0.7316 - 2.08 0.575 - 346.7 1 2 0 -0.0008 9 0 0 0 3.89E+08 4.60E+08 - - - 5.4065 0.9998 221125_WJC_METTL3_EV_vs_WT_F01.17778.17778.2 0.000606 20-Oct K.LIVAYVDDLDR.R "sp|O14776|TCRG1_HUMAN,tr|A0A7P0T8N8|A0A7P0T8N8_HUMAN" 2 1290.682 1.03 5542 17778 2 1290.680646 646.3483 Transcription elongation regulator 1 OS=Homo sapiens OX=9606 GN=TCERG1 PE=1 SV=2 3.93 3476.4 - 824274 - - - -1.0235 - 2.138 0.454 - 391.2 1 2 0 -0.0013 11 0 0 0 1.10E+07 1.06E+07 - - - 4.4495 0.997 221125_WJC_METTL3_EV_vs_WT_F01.17783.17783.2 0.00159 20-Sep K.VITC[160.03]GWDGLIK.L sp|O60508|PRP17_HUMAN 1 1260.6536 1.36 5547 17783 2 1260.648346 631.3341 Pre-mRNA-processing factor 17 OS=Homo sapiens OX=9606 GN=CDC40 PE=1 SV=1 5.8 3477 - 425099 - - - -4.2026 - 1.662 0.438 - 252 1 2 0 -0.0053 11 0 0 0 4.03E+06 2.97E+06 - - - 3.6487 0.9997 221125_WJC_METTL3_EV_vs_WT_F01.17787.17787.2 0.0223 16-Sep R.LIDFLEC[160.03]GK[136.11].T "sp|P17844|DDX5_HUMAN,tr|A0A7I2V5F5|A0A7I2V5F5_HUMAN,tr|J3KRZ1|J3KRZ1_HUMAN,tr|J3QSF1|J3QSF1_HUMAN,tr|A0A7I2V507|A0A7I2V507_HUMAN,tr|J3KTA4|J3KTA4_HUMAN,tr|A0A0G2JLI4|A0A0G2JLI4_HUMAN,tr|A0A7I2V2S0|A0A7I2V2S0_HUMAN" 8 1101.562 0.83 5549 17787 2 1101.560653 551.7883 Probable ATP-dependent RNA helicase DDX5 OS=Homo sapiens OX=9606 GN=DDX5 PE=1 SV=1 4.37 3477.6 - 6.33E+06 - - - -1.2065 - 1.821 0.437 - 217.7 1 2 0 -0.0013 9 0 0 0 3.83E+08 4.60E+08 - - - 4.0023 0.9964 221125_WJC_METTL3_EV_vs_WT_F01.17792.17792.2 0.00401 14-Aug K.MLLVDELR.D "sp|P18085|ARF4_HUMAN,tr|C9JPM4|C9JPM4_HUMAN,tr|C9JAK5|C9JAK5_HUMAN,tr|U3KQF2|U3KQF2_HUMAN" 4 987.5423 0.37 5554 17792 2 987.546138 494.7784 ADP-ribosylation factor 4 OS=Homo sapiens OX=9606 GN=ARF4 PE=1 SV=3 4.37 3477.9 - 1.45E+06 - - - 3.8834 - 1.734 0.342 - 275.4 1 2 0 0.0038 8 0 0 0 4.48E+07 1.22E+08 - - - 3.2259 0.9997 221125_WJC_METTL3_EV_vs_WT_F01.17793.17793.2 0.0001 20-Oct K.LIVAYVDDLDR[166.11].R "sp|O14776|TCRG1_HUMAN,tr|A0A7P0T8N8|A0A7P0T8N8_HUMAN" 2 1300.6902 1.03 5555 17793 2 1300.687964 651.3524 Transcription elongation regulator 1 OS=Homo sapiens OX=9606 GN=TCERG1 PE=1 SV=2 3.93 3478 - 1.32E+06 - - - -1.7475 - 2.029 0.468 - 342.5 1 2 0 -0.0023 11 0 0 0 1.10E+07 1.06E+07 - - - 4.411 0.8074 221125_WJC_METTL3_EV_vs_WT_F01.17799.17799.2 0.103 16-Jul K.LLQDFFNGK.E "sp|P54652|HSP72_HUMAN,sp|P11142|HSP7C_HUMAN,sp|P17066|HSP76_HUMAN,tr|E9PNE6|E9PNE6_HUMAN,tr|A8K7Q2|A8K7Q2_HUMAN,tr|E9PKE3|E9PKE3_HUMAN,tr|E9PN89|E9PN89_HUMAN" 7 1080.5604 0.1 5561 17799 2 1080.554404 541.2875 Heat shock-related 70 kDa protein 2 OS=Homo sapiens OX=9606 GN=HSPA2 PE=1 SV=1 5.84 3478.8 - 490847 - - - -5.5443 - 1.15 0.176 - 97.9 1 2 0 -0.006 9 0 0 0 4.97E+06 4.77E+07 - - - 0.7434 0.9989 221125_WJC_METTL3_EV_vs_WT_F01.17800.17800.2 0.779 12-Jul K.ILVDLLK.L "sp|Q6P582|MZT2A_HUMAN,sp|Q6NZ67|MZT2B_HUMAN,tr|H7C202|H7C202_HUMAN,tr|B8ZZ87|B8ZZ87_HUMAN,tr|A0A494C0V9|A0A494C0V9_HUMAN,tr|H7BZ50|H7BZ50_HUMAN,tr|H7C173|H7C173_HUMAN" 7 812.5371 2.05 5562 17800 2 812.536864 407.2758 Mitotic-spindle organizing protein 2A OS=Homo sapiens OX=9606 GN=MZT2A PE=1 SV=2 5.84 3478.9 - 489553 - - - -0.3409 - 1.721 0.203 - 101.1 1 2 0 -0.0003 7 0 0 0 3.03E+07 1.47E+07 - - - 2.2605 0.9981 221125_WJC_METTL3_EV_vs_WT_F01.17803.17803.2 0.146 16-Aug K.TLGILGLGR.L "sp|O43175|SERA_HUMAN,sp|Q13363|CTBP1_HUMAN,tr|A0A286YF78|A0A286YF78_HUMAN,tr|A0A2C9F2M7|A0A2C9F2M7_HUMAN,tr|A0A286YF22|A0A286YF22_HUMAN,tr|H0Y9M9|H0Y9M9_HUMAN,tr|A0A286YFL2|A0A286YFL2_HUMAN,tr|A0A286YFA2|A0A286YFA2_HUMAN,tr|D6RAX2|D6RAX2_HUMAN,tr|A0A286YFM8|A0A286YFM8_HUMAN,tr|A0A286YFE1|A0A286YFE1_HUMAN" 11 898.56 1.2 5563 17803 2 898.559057 450.2873 D-3-phosphoglycerate dehydrogenase OS=Homo sapiens OX=9606 GN=PHGDH PE=1 SV=4 9.41 3479.3 - 1.45E+07 - - - -1.0517 - 1.696 0.193 - 197 1 2 0 -0.0009 9 0 0 0 6.14E+08 5.13E+08 - - - 1.9945 0.9997 221125_WJC_METTL3_EV_vs_WT_F01.17804.17804.2 0.0162 14-Sep K.MLLVDELR[166.11].D "sp|P18085|ARF4_HUMAN,tr|C9JPM4|C9JPM4_HUMAN,tr|C9JAK5|C9JAK5_HUMAN,tr|U3KQF2|U3KQF2_HUMAN" 4 997.5506 0.37 5564 17804 2 997.550112 499.7826 ADP-ribosylation factor 4 OS=Homo sapiens OX=9606 GN=ARF4 PE=1 SV=3 4.37 3479.4 - 4.85E+06 - - - -0.4621 - 1.86 0.348 - 395.6 1 2 0 -0.0005 8 0 0 0 4.49E+07 1.23E+08 - - - 3.4828 0.9996 221125_WJC_METTL3_EV_vs_WT_F01.17806.17806.2 1.15 18-Sep R.VLITTDLLAR[166.11].G "sp|Q14240|IF4A2_HUMAN,sp|P60842|IF4A1_HUMAN,tr|E7EQG2|E7EQG2_HUMAN" 3 1123.684 1.07 5566 17806 2 1123.68409 562.8493 Eukaryotic initiation factor 4A-II OS=Homo sapiens OX=9606 GN=EIF4A2 PE=1 SV=2 5.81 3479.5 - 2.96E+06 - - - 0.0534 - 1.983 0.313 - 259 1 2 0 0.0001 10 0 0 0 5.76E+08 5.37E+08 - - - 3.2638 0.9998 221125_WJC_METTL3_EV_vs_WT_F01.17807.17807.2 0.013 18-Nov R.VLITTDLLAR.G "sp|Q14240|IF4A2_HUMAN,sp|P60842|IF4A1_HUMAN,tr|E7EQG2|E7EQG2_HUMAN" 3 1113.6758 1.07 5567 17807 2 1113.674975 557.8452 Eukaryotic initiation factor 4A-II OS=Homo sapiens OX=9606 GN=EIF4A2 PE=1 SV=2 5.81 3479.5 - 2.46E+06 - - - -0.7049 - 2.193 0.382 - 430.9 1 2 0 -0.0008 10 0 0 0 5.76E+08 5.37E+08 - - - 4.0541 0.9998 221125_WJC_METTL3_EV_vs_WT_F01.17810.17810.2 0.00601 20-Dec R.VVGVLLGSWQK[136.11].K "sp|P51665|PSMD7_HUMAN,tr|H3BNT7|H3BNT7_HUMAN,tr|H3BTM8|H3BTM8_HUMAN" 3 1192.7059 0.62 5570 17810 2 1192.705582 597.3602 26S proteasome non-ATPase regulatory subunit 7 OS=Homo sapiens OX=9606 GN=PSMD7 PE=1 SV=2 8.72 3479.9 - 1.03E+06 - - - -0.3035 - 2.413 0.322 - 499.6 1 2 0 -0.0004 11 0 0 0 3.74E+07 6.06E+07 - - - 3.8021 0.9973 221125_WJC_METTL3_EV_vs_WT_F01.17813.17813.2 0.474 12-Aug K.ILVDLLK[136.11].L "sp|Q6P582|MZT2A_HUMAN,sp|Q6NZ67|MZT2B_HUMAN,tr|H7C202|H7C202_HUMAN,tr|B8ZZ87|B8ZZ87_HUMAN,tr|A0A494C0V9|A0A494C0V9_HUMAN,tr|H7BZ50|H7BZ50_HUMAN,tr|H7C173|H7C173_HUMAN" 7 820.5513 2.06 5573 17813 2 820.550561 411.2829 Mitotic-spindle organizing protein 2A OS=Homo sapiens OX=9606 GN=MZT2A PE=1 SV=2 5.84 3480.2 - 515223 - - - -0.9506 - 1.333 0.233 - 145.1 1 2 0 -0.0008 7 0 0 0 3.02E+07 1.47E+07 - - - 1.6724 0.9015 221125_WJC_METTL3_EV_vs_WT_F01.17814.17814.3 0.935 Jun-36 K.LAVNMVPFPR.L "sp|P04350|TBB4A_HUMAN,sp|Q9BVA1|TBB2B_HUMAN,sp|A6NNZ2|TBB8B_HUMAN,sp|P07437|TBB5_HUMAN,sp|Q13509|TBB3_HUMAN,sp|Q13885|TBB2A_HUMAN,sp|P68371|TBB4B_HUMAN,sp|Q9BUF5|TBB6_HUMAN,sp|Q3ZCM7|TBB8_HUMAN,sp|Q9H4B7|TBB1_HUMAN,tr|A0A0B4J269|A0A0B4J269_HUMAN,tr|Q5ST81|Q5ST81_HUMAN,tr|Q5JP53|Q5JP53_HUMAN,tr|K7ESM5|K7ESM5_HUMAN,tr|A0A075B736|A0A075B736_HUMAN,tr|Q5SQY0|Q5SQY0_HUMAN" 16 1142.627 0.71 5574 17814 3 1142.625532 381.883 Tubulin beta-4A chain OS=Homo sapiens OX=9606 GN=TUBB4A PE=1 SV=2 9.75 3480.4 - 397129 - - - -1.3154 - 1.462 0.115 - 57.8 7 2 0 -0.0015 10 0 0 0 8.73E+06 1.23E+07 - - - 0.5398 0.998 221125_WJC_METTL3_EV_vs_WT_F01.17820.17820.2 0.00355 14-Jul R.DVDFELIK.V "sp|P48643|TCPE_HUMAN,tr|E9PCA1|E9PCA1_HUMAN,tr|B7ZAR1|B7ZAR1_HUMAN,tr|E7ENZ3|E7ENZ3_HUMAN" 4 977.507 0.65 5578 17820 2 977.506968 489.7608 T-complex protein 1 subunit epsilon OS=Homo sapiens OX=9606 GN=CCT5 PE=1 SV=1 4.03 3481.1 - 5.92E+06 - - - 0.0051 - 1.394 0.237 - 113.2 1 2 0 0 8 0 0 0 9.57E+08 1.48E+09 - - - 1.7933 0.9728 221125_WJC_METTL3_EV_vs_WT_F01.17821.17821.2 0.039 16-Jul K.GNLLLTGDK.D "sp|Q5T4S7|UBR4_HUMAN,tr|X6R960|X6R960_HUMAN" 2 929.5182 2.72 5579 17821 2 929.517918 465.7664 E3 ubiquitin-protein ligase UBR4 OS=Homo sapiens OX=9606 GN=UBR4 PE=1 SV=1 5.84 3481.2 - 2.94E+06 - - - -0.2991 - 1.288 0.025 - 163.9 1 2 0 -0.0003 9 0 0 0 5.75E+07 2.11E+07 - - - -0.0422 0.9998 221125_WJC_METTL3_EV_vs_WT_F01.17824.17824.2 7.53E-05 14/20 R.VVGVLLGSWQK.K "sp|P51665|PSMD7_HUMAN,tr|H3BNT7|H3BNT7_HUMAN,tr|H3BTM8|H3BTM8_HUMAN" 3 1184.6917 0.62 5582 17824 2 1184.689387 593.3531 26S proteasome non-ATPase regulatory subunit 7 OS=Homo sapiens OX=9606 GN=PSMD7 PE=1 SV=2 8.72 3481.5 - 1.12E+06 - - - -1.9895 - 2.451 0.483 - 705.3 1 2 0 -0.0024 11 0 0 0 3.74E+07 6.06E+07 - - - 5.0329 0.8211 221125_WJC_METTL3_EV_vs_WT_F01.17825.17825.2 0.117 18-Aug N.MVVDAVLAIK.Y "sp|P17987|TCPA_HUMAN,tr|E7EQR6|E7EQR6_HUMAN,tr|E7ERF2|E7ERF2_HUMAN" 3 1057.6206 0.44 5583 17825 2 1057.622284 529.8176 T-complex protein 1 subunit alpha OS=Homo sapiens OX=9606 GN=TCP1 PE=1 SV=1 5.59 3481.6 - 953481 - - - 1.6367 - 1.488 0.225 - 160.9 1 1 0 0.0017 10 0 0 0 2.29E+07 5.24E+07 - - - 1.8117 0.9984 221125_WJC_METTL3_EV_vs_WT_F01.17826.17826.2 0.0521 18-Jul K.ILDATPAC[160.03]LP.- "sp|Q9Y5Y2|NUBP2_HUMAN,tr|B7Z6P0|B7Z6P0_HUMAN,tr|H3BQR2|H3BQR2_HUMAN" 3 1069.5478 - 5584 17826 2 1069.547294 535.7812 Cytosolic Fe-S cluster assembly factor NUBP2 OS=Homo sapiens OX=9606 GN=NUBP2 PE=1 SV=1 3.8 3481.7 - 833392 - - - -0.4563 - 1.255 0.31 - 101.8 1 2 0 -0.0005 10 0 0 0 - - - - - 1.9645 0.9942 221125_WJC_METTL3_EV_vs_WT_F01.17827.17827.3 0.165 Oct-36 K.LAVNMVPFPR[166.11].L "sp|P04350|TBB4A_HUMAN,sp|Q9BVA1|TBB2B_HUMAN,sp|A6NNZ2|TBB8B_HUMAN,sp|P07437|TBB5_HUMAN,sp|Q13509|TBB3_HUMAN,sp|Q13885|TBB2A_HUMAN,sp|P68371|TBB4B_HUMAN,sp|Q9BUF5|TBB6_HUMAN,sp|Q3ZCM7|TBB8_HUMAN,sp|Q9H4B7|TBB1_HUMAN,tr|A0A0B4J269|A0A0B4J269_HUMAN,tr|Q5ST81|Q5ST81_HUMAN,tr|Q5JP53|Q5JP53_HUMAN,tr|K7ESM5|K7ESM5_HUMAN,tr|A0A075B736|A0A075B736_HUMAN,tr|Q5SQY0|Q5SQY0_HUMAN" 16 1152.6353 0.71 5585 17827 3 1152.634259 385.219 Tubulin beta-4A chain OS=Homo sapiens OX=9606 GN=TUBB4A PE=1 SV=2 9.75 3481.8 - 747741 - - - -0.9075 - 1.658 0.191 - 213.3 1 2 0 -0.001 10 0 0 0 8.73E+06 1.24E+07 - - - 2.1458 0.9994 221125_WJC_METTL3_EV_vs_WT_F01.17834.17834.2 0.0286 12-Aug R.LDFNLIR.V "sp|P31939|PUR9_HUMAN,tr|C9JLK0|C9JLK0_HUMAN" 2 889.5022 0.75 5590 17834 2 889.502648 445.7584 Bifunctional purine biosynthesis protein ATIC OS=Homo sapiens OX=9606 GN=ATIC PE=1 SV=3 5.84 3482.6 - 1.08E+06 - - - 0.5576 - 1.733 0.283 - 205.9 1 2 0 0.0005 7 0 0 0 6.21E+07 8.30E+07 - - - 2.8733 0.9971 221125_WJC_METTL3_EV_vs_WT_F01.17837.17837.2 0.00116 20-Sep R.SIGVYDVVELK.F "sp|Q8N684|CPSF7_HUMAN,tr|C9J323|C9J323_HUMAN,tr|F5H047|F5H047_HUMAN,tr|F5H669|F5H669_HUMAN,tr|F5H6M0|F5H6M0_HUMAN,tr|J3QT54|J3QT54_HUMAN,tr|C9JM38|C9JM38_HUMAN,tr|C9J286|C9J286_HUMAN" 8 1220.6653 2.24 5593 17837 2 1220.660541 611.3399 Cleavage and polyadenylation specificity factor subunit 7 OS=Homo sapiens OX=9606 GN=CPSF7 PE=1 SV=1 4.37 3482.9 - 756701 - - - -3.8618 - 1.483 0.448 - 200.8 1 2 0 -0.0047 11 0 0 0 1.20E+07 5.38E+06 - - - 3.4145 0.9917 221125_WJC_METTL3_EV_vs_WT_F01.17840.17840.2 0.304 22-Jul R.VVLEGGIDPILR.G "sp|P05164|PERM_HUMAN,tr|J3QSF7|J3QSF7_HUMAN" 2 1279.75 999 5594 17840 2 1279.751527 640.8823 Myeloperoxidase OS=Homo sapiens OX=9606 GN=MPO PE=1 SV=1 4.37 3483.3 - 199700 - - - 1.2034 - 1.497 0.123 - 120.8 1 2 0 0.0015 12 0 0 0 3.41E+06 0.00E+00 - - - 1.0106 0.9964 221125_WJC_METTL3_EV_vs_WT_F01.17842.17842.2 0.358 16-Oct K.TLGILGLGR[166.11].L "sp|O43175|SERA_HUMAN,sp|Q13363|CTBP1_HUMAN,tr|A0A286YF78|A0A286YF78_HUMAN,tr|A0A2C9F2M7|A0A2C9F2M7_HUMAN,tr|A0A286YF22|A0A286YF22_HUMAN,tr|H0Y9M9|H0Y9M9_HUMAN,tr|A0A286YFL2|A0A286YFL2_HUMAN,tr|A0A286YFA2|A0A286YFA2_HUMAN,tr|D6RAX2|D6RAX2_HUMAN,tr|A0A286YFM8|A0A286YFM8_HUMAN,tr|A0A286YFE1|A0A286YFE1_HUMAN" 11 908.5683 1.2 5595 17842 2 908.567832 455.2914 D-3-phosphoglycerate dehydrogenase OS=Homo sapiens OX=9606 GN=PHGDH PE=1 SV=4 9.41 3483.5 - 2.68E+07 - - - -0.4843 - 1.575 0.136 - 321.6 1 2 0 -0.0004 9 0 0 0 6.13E+08 5.13E+08 - - - 1.3595 0.9437 221125_WJC_METTL3_EV_vs_WT_F01.17843.17843.2 0.00475 14/26 R.GLTLAPGLSPARPL.F sp|Q8IU81|I2BP1_HUMAN 1 1361.8031 1.79 5596 17843 2 1361.805294 681.9088 Interferon regulatory factor 2-binding protein 1 OS=Homo sapiens OX=9606 GN=IRF2BP1 PE=1 SV=1 9.75 3483.6 - 567149 - - - 1.6221 - 1.855 0.319 - 467.4 1 1 0 0.0022 14 0 0 0 1.14E+07 6.36E+06 - - - 2.947 0.9815 221125_WJC_METTL3_EV_vs_WT_F01.17847.17847.2 0.003 18-Oct N.MVVDAVLAIK[136.11].Y "sp|P17987|TCPA_HUMAN,tr|E7EQR6|E7EQR6_HUMAN,tr|E7ERF2|E7ERF2_HUMAN" 3 1065.6348 0.44 5599 17847 2 1065.634919 533.8247 T-complex protein 1 subunit alpha OS=Homo sapiens OX=9606 GN=TCP1 PE=1 SV=1 5.59 3484.1 - 3.14E+06 - - - 0.1558 - 1.749 0.398 - 228.6 1 1 0 0.0002 10 0 0 0 2.29E+07 5.24E+07 - - - 3.541 0.9996 221125_WJC_METTL3_EV_vs_WT_F01.17849.17849.2 0.0601 14-Sep K.MAILQIMK[136.11].E "sp|Q13263|TIF1B_HUMAN,tr|M0R3C0|M0R3C0_HUMAN" 2 954.5486 0.7 5600 17849 2 954.548412 478.2816 Transcription intermediary factor 1-beta OS=Homo sapiens OX=9606 GN=TRIM28 PE=1 SV=5 8.5 3484.3 - 1.32E+06 - - - -0.176 - 1.883 0.304 - 254.2 1 2 0 -0.0002 8 0 0 0 8.89E+07 1.27E+08 - - - 3.195 0.9999 221125_WJC_METTL3_EV_vs_WT_F01.17850.17850.2 0.000314 13/28 R.IITGPAPVLPPAALR.T "sp|Q96PU8|QKI_HUMAN,tr|H0YG47|H0YG47_HUMAN,tr|H0YGD6|H0YGD6_HUMAN" 3 1484.9079 2.49 5601 17850 2 1484.906984 743.4612 Protein quaking OS=Homo sapiens OX=9606 GN=QKI PE=1 SV=1 9.75 3484.4 - 913999 - - - -0.6068 - 2.28 0.548 - 374.9 1 2 0 -0.0009 15 0 0 0 3.03E+07 1.22E+07 - - - 5.1145 0.9965 221125_WJC_METTL3_EV_vs_WT_F01.17852.17852.2 0.00897 22-Oct R.LLTFNPTYC[160.03]ALK[136.11].E sp|Q14139|UBE4A_HUMAN 1 1447.7625 1.14 5603 17852 2 1447.756773 724.8885 Ubiquitin conjugation factor E4 A OS=Homo sapiens OX=9606 GN=UBE4A PE=1 SV=2 8.2 3484.7 - 339033 - - - -3.9371 - 1.881 0.35 - 258.9 1 2 0 -0.0057 12 0 0 0 6.77E+06 5.92E+06 - - - 3.2867 0.9878 221125_WJC_METTL3_EV_vs_WT_F01.17854.17854.2 0.00817 16-Sep R.VC[160.03]MDFNIIR.K "sp|P41252|SYIC_HUMAN,tr|A0A804HL54|A0A804HL54_HUMAN,tr|A0A804HKU1|A0A804HKU1_HUMAN,tr|A0A804HK69|A0A804HK69_HUMAN,tr|A0A804HIV9|A0A804HIV9_HUMAN,tr|A0A804HJN6|A0A804HJN6_HUMAN,tr|A0A804HHW9|A0A804HHW9_HUMAN,tr|A0A0A0MSX9|A0A0A0MSX9_HUMAN,tr|J3KR24|J3KR24_HUMAN,tr|A0A804HIG2|A0A804HIG2_HUMAN,tr|A0A804HJ36|A0A804HJ36_HUMAN" 11 1166.5576 2.05 5605 17854 2 1166.552542 584.2861 "Isoleucine--tRNA ligase, cytoplasmic OS=Homo sapiens OX=9606 GN=IARS1 PE=1 SV=2" 5.8 3485 - 243224 - - - -4.3658 - 1.461 0.301 - 161.1 1 2 0 -0.0051 9 0 0 0 4.76E+06 2.32E+06 - - - 2.3594 0.999 221125_WJC_METTL3_EV_vs_WT_F01.17857.17857.2 0.000346 14-Sep K.MAILQIMK.E "sp|Q13263|TIF1B_HUMAN,tr|M0R3C0|M0R3C0_HUMAN" 2 946.5344 0.7 5606 17857 2 946.53269 474.2745 Transcription intermediary factor 1-beta OS=Homo sapiens OX=9606 GN=TRIM28 PE=1 SV=5 8.5 3485.4 - 1.57E+06 - - - -1.7855 - 1.864 0.275 - 251.8 1 2 0 -0.0017 8 0 0 0 8.89E+07 1.27E+08 - - - 2.9497 0.9666 221125_WJC_METTL3_EV_vs_WT_F01.17858.17858.2 1.11 12-Jun R.SILEYLR.V sp|Q8N1G4|LRC47_HUMAN 1 892.5018 0.68 5607 17858 2 892.500577 447.2582 Leucine-rich repeat-containing protein 47 OS=Homo sapiens OX=9606 GN=LRRC47 PE=1 SV=1 5.72 3485.5 - 1.14E+06 - - - -1.3905 - 1.2 0.06 - 138.9 1 2 0 -0.0012 7 0 0 0 5.65E+07 8.34E+07 - - - 0.0615 0.9999 221125_WJC_METTL3_EV_vs_WT_F01.17859.17859.2 2.32E-07 16-Nov K.YMAEALLLR.A sp|O94826|TOM70_HUMAN 1 1078.5845 2.99 5608 17859 2 1078.583195 540.2995 Mitochondrial import receptor subunit TOM70 OS=Homo sapiens OX=9606 GN=TOMM70 PE=1 SV=1 6 3485.6 - 1.27E+06 - - - -1.2118 - 2.204 0.533 - 463.1 1 2 0 -0.0013 9 0 0 0 2.49E+07 8.33E+06 - - - 5.2636 0.9998 221125_WJC_METTL3_EV_vs_WT_F01.17868.17868.2 0.00801 20-Nov K.LLELALQQYPR[166.11].G sp|Q96KC8|DNJC1_HUMAN 1 1352.7692 1.05 5615 17868 2 1352.769261 677.3919 DnaJ homolog subfamily C member 1 OS=Homo sapiens OX=9606 GN=DNAJC1 PE=1 SV=1 6 3486.7 - 230416 - - - 0.0776 - 2.391 0.372 - 551.7 1 2 0 0.0001 11 0 0 0 7.95E+06 7.61E+06 - - - 4.1467 0.9997 221125_WJC_METTL3_EV_vs_WT_F01.17871.17871.2 0.00452 16-Sep K.GIFLGDQWR[166.11].D "sp|Q14671|PUM1_HUMAN,tr|Q5T1Z8|Q5T1Z8_HUMAN,tr|H0YEH2|H0YEH2_HUMAN,tr|Q5T1Z4|Q5T1Z4_HUMAN" 4 1100.5642 1.76 5616 17871 2 1100.563964 551.2894 Pumilio homolog 1 OS=Homo sapiens OX=9606 GN=PUM1 PE=1 SV=3 5.84 3487.1 - 1.91E+07 - - - -0.259 - 1.6 0.423 - 290.5 1 2 0 -0.0003 9 0 0 0 7.05E+08 4.01E+08 - - - 3.5249 0.9966 221125_WJC_METTL3_EV_vs_WT_F01.17873.17873.2 0.042 16-Sep K.TGPLLIELR[166.11].G sp|Q9Y6W3|CAN7_HUMAN 1 1020.6207 0.64 5618 17873 2 1020.619838 511.3176 Calpain-7 OS=Homo sapiens OX=9606 GN=CAPN7 PE=1 SV=1 5.66 3487.4 - 214529 - - - -0.8456 - 1.183 0.265 - 153.9 1 2 0 -0.0009 9 0 0 0 2.72E+06 4.27E+06 - - - 1.4842 0.9991 221125_WJC_METTL3_EV_vs_WT_F01.17882.17882.2 0.025 14-Aug R.DVDFELIK[136.11].V "sp|P48643|TCPE_HUMAN,tr|E9PCA1|E9PCA1_HUMAN,tr|B7ZAR1|B7ZAR1_HUMAN,tr|E7ENZ3|E7ENZ3_HUMAN" 4 985.5212 0.67 5624 17882 2 985.520491 493.7679 T-complex protein 1 subunit epsilon OS=Homo sapiens OX=9606 GN=CCT5 PE=1 SV=1 4.03 3488.4 - 6.51E+07 - - - -0.6819 - 1.375 0.336 - 162.4 1 2 0 -0.0007 8 0 0 0 9.53E+08 1.42E+09 - - - 2.4829 0.9993 221125_WJC_METTL3_EV_vs_WT_F01.17884.17884.2 0.00891 13/22 K.IPGIIIAASAVR[166.11].A "sp|P33992|MCM5_HUMAN,tr|B1AHB1|B1AHB1_HUMAN,tr|B1AHA9|B1AHA9_HUMAN,tr|B1AHB2|B1AHB2_HUMAN" 4 1189.7422 0.53 5626 17884 2 1189.746495 595.8784 DNA replication licensing factor MCM5 OS=Homo sapiens OX=9606 GN=MCM5 PE=1 SV=5 9.75 3488.6 - 1.63E+06 - - - 3.5991 - 2.54 0.492 - 644.4 1 2 0 0.0043 12 0 0 0 3.06E+07 5.77E+07 - - - 5.1262 0.9924 221125_WJC_METTL3_EV_vs_WT_F01.17888.17888.2 5.41E-07 22-Oct A.LVMLQEDELLSK.M sp|Q96A49|SYAP1_HUMAN 1 1416.7534 1.36 5630 17888 2 1416.751598 709.384 Synapse-associated protein 1 OS=Homo sapiens OX=9606 GN=SYAP1 PE=1 SV=1 4.14 3489.1 - 242448 - - - -1.2846 - 2.378 0.549 - 316.2 1 1 0 -0.0018 12 0 0 0 8.37E+06 6.14E+06 - - - 5.3746 0.9993 221125_WJC_METTL3_EV_vs_WT_F01.17889.17889.3 0.00141 Oct-44 K.IPGIIIAASAVR[166.11].A "sp|P33992|MCM5_HUMAN,tr|B1AHB1|B1AHB1_HUMAN,tr|B1AHA9|B1AHA9_HUMAN,tr|B1AHB2|B1AHB2_HUMAN" 4 1189.7422 0.32 5631 17889 3 1189.742296 397.588 DNA replication licensing factor MCM5 OS=Homo sapiens OX=9606 GN=MCM5 PE=1 SV=5 9.75 3489.2 - 121713 - - - 0.0698 - 2.185 0.26 - 117.1 1 2 0 0.0001 12 0 0 0 1.00E+06 3.09E+06 - - - 3.6052 0.9979 221125_WJC_METTL3_EV_vs_WT_F01.17897.17897.3 0.819 Nov-44 R.FLAVGLVDNTVR[166.11].L sp|Q15393|SF3B3_HUMAN 1 1312.7379 1.75 5637 17897 3 1312.737491 438.5866 Splicing factor 3B subunit 3 OS=Homo sapiens OX=9606 GN=SF3B3 PE=1 SV=4 5.84 3490 - 770108 - - - -0.278 - 1.992 0.21 - 145.1 1 2 0 -0.0004 12 0 0 0 2.82E+07 1.62E+07 - - - 2.7914 0.9984 221125_WJC_METTL3_EV_vs_WT_F01.17906.17906.2 0.167 16-Aug K.WMPGITQWK[136.11].V sp|Q08J23|NSUN2_HUMAN 1 1153.5834 0.87 5644 17906 2 1153.583631 577.799 RNA cytosine C(5)-methyltransferase NSUN2 OS=Homo sapiens OX=9606 GN=NSUN2 PE=1 SV=2 8.75 3491.1 - 1.49E+06 - - - 0.2124 - 1.361 0.276 - 227.9 1 2 0 0.0002 9 0 0 0 1.69E+07 1.96E+07 - - - 1.9712 0.9847 221125_WJC_METTL3_EV_vs_WT_F01.17907.17907.2 0.00407 13/22 H.IISELILTAQER.D sp|Q96I24|FUBP3_HUMAN 1 1384.7926 1.95 5645 17907 2 1384.793789 693.4036 Far upstream element-binding protein 3 OS=Homo sapiens OX=9606 GN=FUBP3 PE=1 SV=2 4.53 3491.2 - 1.20E+06 - - - 0.8731 - 2.466 0.355 - 506.2 1 1 0 0.0012 12 0 0 0 3.45E+07 1.77E+07 - - - 4.0375 0.999 221125_WJC_METTL3_EV_vs_WT_F01.17908.17908.2 0.00699 14-Jul R.GFGFVQFK[136.11].N "sp|Q9NW13|RBM28_HUMAN,tr|C9JE21|C9JE21_HUMAN" 2 936.4949 1.1 5646 17908 2 936.496209 469.2547 RNA-binding protein 28 OS=Homo sapiens OX=9606 GN=RBM28 PE=1 SV=3 8.75 3491.3 - 953976 - - - 1.4095 - 1.379 0.385 - 124 1 2 0 0.0013 8 0 0 0 1.66E+07 1.51E+07 - - - 2.8534 0.9859 221125_WJC_METTL3_EV_vs_WT_F01.17910.17910.2 0.0012 16/22 H.IISELILTAQER[166.11].D sp|Q96I24|FUBP3_HUMAN 1 1394.8009 1.89 5648 17910 2 1394.798135 698.4077 Far upstream element-binding protein 3 OS=Homo sapiens OX=9606 GN=FUBP3 PE=1 SV=2 4.53 3491.5 - 625730 - - - -1.9465 - 2.782 0.437 - 1034.4 1 1 0 -0.0027 12 0 0 0 3.33E+07 1.76E+07 - - - 4.96 0.9992 221125_WJC_METTL3_EV_vs_WT_F01.17913.17913.2 2.19E-05 22-Nov R.AAMEALVVEVTK[136.11].Q sp|Q08211|DHX9_HUMAN 1 1267.6937 1.73 5651 17913 2 1267.697016 634.8541 ATP-dependent RNA helicase A OS=Homo sapiens OX=9606 GN=DHX9 PE=1 SV=4 4.53 3491.9 - 281162 - - - 2.5968 - 1.833 0.441 - 313.4 1 2 0 0.0033 12 0 0 0 4.21E+06 2.43E+06 - - - 3.8916 0.9998 221125_WJC_METTL3_EV_vs_WT_F01.17916.17916.2 0.000714 18-Sep K.NPGLWLESVR[166.11].L sp|O94906|PRP6_HUMAN 1 1179.6276 2.15 5652 17916 2 1179.628371 590.8211 Pre-mRNA-processing factor 6 OS=Homo sapiens OX=9606 GN=PRPF6 PE=1 SV=1 6 3492.3 - 1.49E+06 - - - 0.6731 - 1.717 0.5 - 322.4 1 2 0 0.0008 10 0 0 0 4.83E+07 2.24E+07 - - - 4.2427 0.9979 221125_WJC_METTL3_EV_vs_WT_F01.17918.17918.2 0.0813 16-Jul R.ILFLDPSGK[136.11].V sp|O95881|TXD12_HUMAN 1 996.5735 1.25 5654 17918 2 996.574276 499.294 Thioredoxin domain-containing protein 12 OS=Homo sapiens OX=9606 GN=TXNDC12 PE=1 SV=1 5.84 3492.5 - 1.08E+06 - - - 0.7456 - 1.442 0.24 - 107 1 2 0 0.0007 9 0 0 0 1.79E+09 1.44E+09 - - - 1.8724 0.8156 221125_WJC_METTL3_EV_vs_WT_F01.17920.17920.2 0.281 14-Sep V.ILSILLSK.A "sp|Q6UXB4|CLC4G_HUMAN,sp|Q02040|AK17A_HUMAN,tr|A0A7I2V4C7|A0A7I2V4C7_HUMAN,tr|M0R277|M0R277_HUMAN,tr|A0A7I2V4U5|A0A7I2V4U5_HUMAN" 5 885.5899 1.19 5656 17920 2 885.591412 443.8022 C-type lectin domain family 4 member G OS=Homo sapiens OX=9606 GN=CLEC4G PE=1 SV=1 8.75 3492.7 - 653302 - - - 1.7017 - 1.35 0.253 - 189.6 1 1 0 0.0015 8 0 0 0 9.99E+06 8.41E+06 - - - 1.8143 0.948 221125_WJC_METTL3_EV_vs_WT_F01.17921.17921.2 0.492 14-Jul K.GPFLLGIK[136.11].A sp|P21399|ACOHC_HUMAN 1 851.536 0.61 5657 17921 2 851.537887 426.7753 Cytoplasmic aconitate hydratase OS=Homo sapiens OX=9606 GN=ACO1 PE=1 SV=3 8.75 3492.8 - 287030 - - - 2.1866 - 1.413 0.026 - 127.1 2 2 0 0.0019 8 0 0 0 1.82E+06 3.00E+06 - - - 0.1406 0.9844 221125_WJC_METTL3_EV_vs_WT_F01.17924.17924.2 9.15E-05 22-Nov A.LVMLQEDELLSK[136.11].M sp|Q96A49|SYAP1_HUMAN 1 1424.7676 1.36 5659 17924 2 1424.770051 713.3911 Synapse-associated protein 1 OS=Homo sapiens OX=9606 GN=SYAP1 PE=1 SV=1 4.14 3493.1 - 439410 - - - 1.7076 - 2.282 0.466 - 366.2 1 1 0 0.0024 12 0 0 0 8.37E+06 6.14E+06 - - - 4.653 0.9989 221125_WJC_METTL3_EV_vs_WT_F01.17927.17927.2 0.154 14-Sep K.VALLLLEK.E "sp|Q9Y4W6|AFG32_HUMAN,sp|Q01484|ANK2_HUMAN,tr|A0A5F9ZHE4|A0A5F9ZHE4_HUMAN,tr|A0A5F9ZHM6|A0A5F9ZHM6_HUMAN,tr|A0A5F9ZH58|A0A5F9ZH58_HUMAN,tr|A0A5F9ZH38|A0A5F9ZH38_HUMAN,tr|A0A5F9ZHL5|A0A5F9ZHL5_HUMAN,tr|A0A5F9ZH35|A0A5F9ZH35_HUMAN,tr|A0A5F9ZI15|A0A5F9ZI15_HUMAN,tr|A0A5F9ZHY6|A0A5F9ZHY6_HUMAN,tr|A0A5F9ZHJ6|A0A5F9ZHJ6_HUMAN,tr|B7Z651|B7Z651_HUMAN,tr|A0A5F9ZI73|A0A5F9ZI73_HUMAN,tr|A0A5F9ZGX3|A0A5F9ZGX3_HUMAN,tr|A0A5F9ZI56|A0A5F9ZI56_HUMAN,tr|A0A5F9ZGS7|A0A5F9ZGS7_HUMAN,tr|A0A5F9ZH39|A0A5F9ZH39_HUMAN,tr|A0A5F9ZI45|A0A5F9ZI45_HUMAN,tr|A0A5F9ZGY1|A0A5F9ZGY1_HUMAN,tr|A0A5F9ZGZ1|A0A5F9ZGZ1_HUMAN,tr|A0A5F9ZI81|A0A5F9ZI81_HUMAN,tr|A0A5F9ZGY3|A0A5F9ZGY3_HUMAN,tr|A0A5F9ZHJ4|A0A5F9ZHJ4_HUMAN,tr|A0A5F9ZH34|A0A5F9ZH34_HUMAN,tr|A0A5F9ZHS1|A0A5F9ZHS1_HUMAN,tr|D6RHE1|D6RHE1_HUMAN,tr|A0A5F9ZI65|A0A5F9ZI65_HUMAN,tr|A0A5F9ZHC9|A0A5F9ZHC9_HUMAN,tr|A0A5F9ZI53|A0A5F9ZI53_HUMAN,tr|A0A5F9ZH70|A0A5F9ZH70_HUMAN,tr|A0A5F9ZHN5|A0A5F9ZHN5_HUMAN,tr|A0A5F9ZI40|A0A5F9ZI40_HUMAN,tr|A0A5F9ZGY4|A0A5F9ZGY4_HUMAN,tr|A0A5F9ZHR8|A0A5F9ZHR8_HUMAN,tr|A0A5F9ZHR2|A0A5F9ZHR2_HUMAN,tr|E9PHW9|E9PHW9_HUMAN,tr|A0A5F9ZHG3|A0A5F9ZHG3_HUMAN,tr|A0A5F9ZHA1|A0A5F9ZHA1_HUMAN,tr|A0A5F9ZH30|A0A5F9ZH30_HUMAN,tr|A0A5F9ZI69|A0A5F9ZI69_HUMAN,tr|A0A5F9ZI18|A0A5F9ZI18_HUMAN,tr|A0A5F9ZGS5|A0A5F9ZGS5_HUMAN,tr|A0A5F9ZI30|A0A5F9ZI30_HUMAN,tr|I6L894|I6L894_HUMAN,tr|A0A5F9ZHQ5|A0A5F9ZHQ5_HUMAN,tr|A0A0U1RQN6|A0A0U1RQN6_HUMAN,tr|A0A5F9ZH19|A0A5F9ZH19_HUMAN,tr|A0A5F9ZHL9|A0A5F9ZHL9_HUMAN,tr|A0A5F9ZGX8|A0A5F9ZGX8_HUMAN,tr|A0A5F9ZGZ5|A0A5F9ZGZ5_HUMAN,tr|A0A5F9ZHD2|A0A5F9ZHD2_HUMAN" 51 897.5899 1.15 5661 17927 2 897.590595 449.8022 AFG3-like protein 2 OS=Homo sapiens OX=9606 GN=AFG3L2 PE=1 SV=2 5.97 3493.4 - 3.27E+06 - - - 0.7687 - 1.726 0.234 - 315.1 1 2 0 0.0007 8 0 0 0 4.24E+07 3.68E+07 - - - 2.4152 0.9984 221125_WJC_METTL3_EV_vs_WT_F01.17929.17929.2 0.161 18-Oct R.ILELDQELIK[136.11].A "sp|Q92878|RAD50_HUMAN,tr|E7EN38|E7EN38_HUMAN,tr|A0A494BZX5|A0A494BZX5_HUMAN,tr|A0A494C1B7|A0A494C1B7_HUMAN,tr|E7ESD9|E7ESD9_HUMAN,tr|A0A494C122|A0A494C122_HUMAN,tr|A0A494C0Y7|A0A494C0Y7_HUMAN,tr|A0A1W2PQ90|A0A1W2PQ90_HUMAN" 8 1220.7108 1.29 5663 17929 2 1220.712403 611.3627 DNA repair protein RAD50 OS=Homo sapiens OX=9606 GN=RAD50 PE=1 SV=1 4.14 3493.5 - 936922 - - - 1.35 - 1.813 0.227 - 226 1 2 0 0.0016 10 0 0 0 3.46E+07 2.68E+07 - - - 2.3779 0.9994 221125_WJC_METTL3_EV_vs_WT_F01.17930.17930.2 0.0216 16-Oct R.SLIAEVLVK.L sp|O95969|SG1D2_HUMAN 1 970.6063 324.02 5664 17930 2 970.606023 486.3104 Secretoglobin family 1D member 2 OS=Homo sapiens OX=9606 GN=SCGB1D2 PE=2 SV=1 5.72 3493.6 - 823282 - - - -0.2679 - 1.79 0.29 - 279.3 1 2 0 -0.0003 9 0 0 0 1.48E+08 4.58E+05 - - - 2.8672 0.973 221125_WJC_METTL3_EV_vs_WT_F01.17938.17938.2 0.0378 20-Oct K.NLIDAGVDALR[166.11].V "sp|P12268|IMDH2_HUMAN,tr|A0A7I2YQK5|A0A7I2YQK5_HUMAN,tr|H0Y4R1|H0Y4R1_HUMAN,tr|A0A7I2V2T3|A0A7I2V2T3_HUMAN,tr|E7ETK5|E7ETK5_HUMAN" 5 1165.6331 0.28 5670 17938 2 1165.626956 583.8238 Inosine-5'-monophosphate dehydrogenase 2 OS=Homo sapiens OX=9606 GN=IMPDH2 PE=1 SV=2 4.21 3494.7 - 2.37E+06 - - - -5.2341 - 1.919 0.189 - 254.6 1 2 0 -0.0061 11 0 0 0 7.61E+06 2.71E+07 - - - 2.1983 0.9995 221125_WJC_METTL3_EV_vs_WT_F01.17939.17939.2 0.000318 16-Sep R.YYIDADLLR.E sp|Q7Z3B4|NUP54_HUMAN 1 1140.5815 2.45 5671 17939 2 1140.583254 571.298 Nucleoporin p54 OS=Homo sapiens OX=9606 GN=NUP54 PE=1 SV=2 4.21 3494.8 - 2.09E+06 - - - 1.5159 - 1.622 0.426 - 244.2 1 2 0 0.0017 9 0 0 0 2.13E+08 8.71E+07 - - - 3.5861 0.9984 221125_WJC_METTL3_EV_vs_WT_F01.17940.17940.2 0.522 14-Sep K.VALLLLEK[136.11].E "sp|Q9Y4W6|AFG32_HUMAN,sp|Q01484|ANK2_HUMAN,tr|A0A5F9ZHE4|A0A5F9ZHE4_HUMAN,tr|A0A5F9ZHM6|A0A5F9ZHM6_HUMAN,tr|A0A5F9ZH58|A0A5F9ZH58_HUMAN,tr|A0A5F9ZH38|A0A5F9ZH38_HUMAN,tr|A0A5F9ZHL5|A0A5F9ZHL5_HUMAN,tr|A0A5F9ZH35|A0A5F9ZH35_HUMAN,tr|A0A5F9ZI15|A0A5F9ZI15_HUMAN,tr|A0A5F9ZHY6|A0A5F9ZHY6_HUMAN,tr|A0A5F9ZHJ6|A0A5F9ZHJ6_HUMAN,tr|B7Z651|B7Z651_HUMAN,tr|A0A5F9ZI73|A0A5F9ZI73_HUMAN,tr|A0A5F9ZGX3|A0A5F9ZGX3_HUMAN,tr|A0A5F9ZI56|A0A5F9ZI56_HUMAN,tr|A0A5F9ZGS7|A0A5F9ZGS7_HUMAN,tr|A0A5F9ZH39|A0A5F9ZH39_HUMAN,tr|A0A5F9ZI45|A0A5F9ZI45_HUMAN,tr|A0A5F9ZGY1|A0A5F9ZGY1_HUMAN,tr|A0A5F9ZGZ1|A0A5F9ZGZ1_HUMAN,tr|A0A5F9ZI81|A0A5F9ZI81_HUMAN,tr|A0A5F9ZGY3|A0A5F9ZGY3_HUMAN,tr|A0A5F9ZHJ4|A0A5F9ZHJ4_HUMAN,tr|A0A5F9ZH34|A0A5F9ZH34_HUMAN,tr|A0A5F9ZHS1|A0A5F9ZHS1_HUMAN,tr|D6RHE1|D6RHE1_HUMAN,tr|A0A5F9ZI65|A0A5F9ZI65_HUMAN,tr|A0A5F9ZHC9|A0A5F9ZHC9_HUMAN,tr|A0A5F9ZI53|A0A5F9ZI53_HUMAN,tr|A0A5F9ZH70|A0A5F9ZH70_HUMAN,tr|A0A5F9ZHN5|A0A5F9ZHN5_HUMAN,tr|A0A5F9ZI40|A0A5F9ZI40_HUMAN,tr|A0A5F9ZGY4|A0A5F9ZGY4_HUMAN,tr|A0A5F9ZHR8|A0A5F9ZHR8_HUMAN,tr|A0A5F9ZHR2|A0A5F9ZHR2_HUMAN,tr|E9PHW9|E9PHW9_HUMAN,tr|A0A5F9ZHG3|A0A5F9ZHG3_HUMAN,tr|A0A5F9ZHA1|A0A5F9ZHA1_HUMAN,tr|A0A5F9ZH30|A0A5F9ZH30_HUMAN,tr|A0A5F9ZI69|A0A5F9ZI69_HUMAN,tr|A0A5F9ZI18|A0A5F9ZI18_HUMAN,tr|A0A5F9ZGS5|A0A5F9ZGS5_HUMAN,tr|A0A5F9ZI30|A0A5F9ZI30_HUMAN,tr|I6L894|I6L894_HUMAN,tr|A0A5F9ZHQ5|A0A5F9ZHQ5_HUMAN,tr|A0A0U1RQN6|A0A0U1RQN6_HUMAN,tr|A0A5F9ZH19|A0A5F9ZH19_HUMAN,tr|A0A5F9ZHL9|A0A5F9ZHL9_HUMAN,tr|A0A5F9ZGX8|A0A5F9ZGX8_HUMAN,tr|A0A5F9ZGZ5|A0A5F9ZGZ5_HUMAN,tr|A0A5F9ZHD2|A0A5F9ZHD2_HUMAN" 51 905.6041 1.16 5672 17940 2 905.604447 453.8093 AFG3-like protein 2 OS=Homo sapiens OX=9606 GN=AFG3L2 PE=1 SV=2 5.97 3494.9 - 1.97E+06 - - - 0.3776 - 2.136 0.096 - 283.8 1 2 0 0.0003 8 0 0 0 4.26E+07 3.67E+07 - - - 2.0389 0.9994 221125_WJC_METTL3_EV_vs_WT_F01.17941.17941.2 5.19E-05 18-Sep R.YLYTLVITDK.E "sp|P63173|RL38_HUMAN,tr|J3KT73|J3KT73_HUMAN,tr|J3QL01|J3QL01_HUMAN" 3 1227.6751 1.12 5673 17941 2 1227.676066 614.8448 60S ribosomal protein L38 OS=Homo sapiens OX=9606 GN=RPL38 PE=1 SV=2 5.83 3494.9 - 1.68E+06 - - - 0.7942 - 1.59 0.366 - 223.9 1 2 0 0.001 10 0 0 0 1.55E+09 1.39E+09 - - - 3.0384 0.9995 221125_WJC_METTL3_EV_vs_WT_F01.17942.17942.2 0.00355 16-Aug R.YYIDADLLR[166.11].E sp|Q7Z3B4|NUP54_HUMAN 1 1150.5898 2.59 5674 17942 2 1150.590654 576.3022 Nucleoporin p54 OS=Homo sapiens OX=9606 GN=NUP54 PE=1 SV=2 4.21 3495 - 1.67E+06 - - - 0.7466 - 1.557 0.39 - 182.9 1 2 0 0.0009 9 0 0 0 2.11E+08 8.16E+07 - - - 3.2022 0.9988 221125_WJC_METTL3_EV_vs_WT_F01.17943.17943.2 0.0385 18-Nov R.ILELDQELIK.A "sp|Q92878|RAD50_HUMAN,tr|E7EN38|E7EN38_HUMAN,tr|A0A494BZX5|A0A494BZX5_HUMAN,tr|A0A494C1B7|A0A494C1B7_HUMAN,tr|E7ESD9|E7ESD9_HUMAN,tr|A0A494C122|A0A494C122_HUMAN,tr|A0A494C0Y7|A0A494C0Y7_HUMAN,tr|A0A1W2PQ90|A0A1W2PQ90_HUMAN" 8 1212.6966 1.28 5675 17943 2 1212.699082 607.3556 DNA repair protein RAD50 OS=Homo sapiens OX=9606 GN=RAD50 PE=1 SV=1 4.14 3495.1 - 1.50E+06 - - - 2.0838 - 2.069 0.267 - 223.4 1 2 0 0.0025 10 0 0 0 3.55E+07 2.78E+07 - - - 3.0417 0.9997 221125_WJC_METTL3_EV_vs_WT_F01.17944.17944.2 2.21E-06 20-Sep K.FGEPVLAGFAR[166.11].S sp|O15067|PUR4_HUMAN 1 1172.6218 0.72 5676 17944 2 1172.62293 587.3182 Phosphoribosylformylglycinamidine synthase OS=Homo sapiens OX=9606 GN=PFAS PE=1 SV=4 6 3495.1 - 1.44E+06 - - - 0.9944 - 2.068 0.426 - 368.6 1 2 0 0.0012 11 0 0 0 3.01E+07 4.18E+07 - - - 4.1526 0.9983 221125_WJC_METTL3_EV_vs_WT_F01.17948.17948.2 0.0532 14-Jul R.TLEFQVFR[166.11].N sp|Q92545|TM131_HUMAN 1 1048.5581 2.37 5680 17948 2 1048.559622 525.2863 Transmembrane protein 131 OS=Homo sapiens OX=9606 GN=TMEM131 PE=1 SV=3 5.66 3495.6 - 508226 - - - 1.4506 - 1.253 0.357 - 164.3 1 2 0 0.0015 8 0 0 0 1.46E+07 6.14E+06 - - - 2.3575 0.9999 221125_WJC_METTL3_EV_vs_WT_F01.17950.17950.2 7.82E-05 26-Nov K.IIVPNSTAGLIIGK[136.11].G "sp|P51513|NOVA1_HUMAN,sp|Q9UNW9|NOVA2_HUMAN,tr|F8VW64|F8VW64_HUMAN,tr|F8VWX1|F8VWX1_HUMAN,tr|M0R1A0|M0R1A0_HUMAN,tr|J3KQU3|J3KQU3_HUMAN,tr|A0A6Q8PFC2|A0A6Q8PFC2_HUMAN,tr|G8JLA5|G8JLA5_HUMAN" 8 1402.8639 0.52 5682 17950 2 1402.863463 702.4392 RNA-binding protein Nova-1 OS=Homo sapiens OX=9606 GN=NOVA1 PE=1 SV=2 8.75 3495.9 - 258745 - - - -0.3122 - 1.988 0.531 - 278.8 1 2 0 -0.0004 14 0 0 0 1.98E+06 3.79E+06 - - - 4.6871 0.9999 221125_WJC_METTL3_EV_vs_WT_F01.17953.17953.2 2.78E-05 22-Dec K.VLETVGVFEVPK[136.11].Q "sp|Q9Y2S7|PDIP2_HUMAN,tr|B4DEM9|B4DEM9_HUMAN" 2 1323.753 1.53 5685 17953 2 1323.751861 662.8838 Polymerase delta-interacting protein 2 OS=Homo sapiens OX=9606 GN=POLDIP2 PE=1 SV=1 4.53 3496.2 - 140303 - - - -0.8257 - 2.147 0.517 - 421.5 1 2 0 -0.0011 12 0 0 0 1.29E+07 8.47E+06 - - - 4.8696 1 221125_WJC_METTL3_EV_vs_WT_F01.17954.17954.2 4.95E-09 Oct-38 K.GNPQGFNQGLDC[160.03]DVIVAEVR[166.11].S sp|Q86U44|MTA70_HUMAN 1 2197.0461 0.001 5686 17954 2 2197.047352 1099.5303 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 4.03 3496.4 - 118578 - - - 0.5535 - 2.44 0.682 - 235.1 1 2 0 0.0012 20 0 0 0 0.00E+00 2.62E+06 - - - 6.2709 0.9889 221125_WJC_METTL3_EV_vs_WT_F01.17957.17957.2 0.107 18-Aug K.LWTMPISSVR[166.11].F "sp|Q86U86|PB1_HUMAN,tr|H0Y5B5|H0Y5B5_HUMAN,tr|E7EVG2|E7EVG2_HUMAN" 3 1198.6408 1.22 5688 17957 2 1198.646213 600.3277 Protein polybromo-1 OS=Homo sapiens OX=9606 GN=PBRM1 PE=1 SV=1 9.75 3496.8 - 587919 - - - 4.5285 - 1.874 0.242 - 172 1 2 0 0.0054 10 0 0 0 4.21E+07 3.44E+07 - - - 2.5799 0.9998 221125_WJC_METTL3_EV_vs_WT_F01.17959.17959.2 0.0191 22-Dec K.IPGIIIAASAVR.A "sp|P33992|MCM5_HUMAN,tr|B1AHB1|B1AHB1_HUMAN,tr|B1AHA9|B1AHA9_HUMAN,tr|B1AHB2|B1AHB2_HUMAN" 4 1179.7339 0.51 5690 17959 2 1179.734696 590.8742 DNA replication licensing factor MCM5 OS=Homo sapiens OX=9606 GN=MCM5 PE=1 SV=5 9.75 3497 - 1.16E+06 - - - 0.6383 - 2.584 0.416 - 486.6 1 2 0 0.0008 12 0 0 0 3.07E+07 5.98E+07 - - - 4.6112 0.9998 221125_WJC_METTL3_EV_vs_WT_F01.17967.17967.2 0.000391 16-Sep R.YLDVSILGK[136.11].F sp|Q86U44|MTA70_HUMAN 1 1014.5841 0.23 5697 17967 2 1014.584563 508.2993 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 5.83 3497.9 - 4.17E+06 - - - 0.4583 - 1.81 0.431 - 190 1 2 0 0.0005 9 0 0 0 3.23E+07 1.43E+08 - - - 3.9407 0.9997 221125_WJC_METTL3_EV_vs_WT_F01.17969.17969.2 0.00478 18-Nov R.YLYTLVITDK[136.11].E "sp|P63173|RL38_HUMAN,tr|J3KT73|J3KT73_HUMAN,tr|J3QL01|J3QL01_HUMAN" 3 1235.6893 1.12 5699 17969 2 1235.690257 618.8519 60S ribosomal protein L38 OS=Homo sapiens OX=9606 GN=RPL38 PE=1 SV=2 5.83 3498.1 - 2.48E+07 - - - 0.7817 - 2.007 0.365 - 312 1 2 0 0.001 10 0 0 0 1.55E+09 1.39E+09 - - - 3.6811 0.9998 221125_WJC_METTL3_EV_vs_WT_F01.17971.17971.2 6.09E-06 18-Nov K.APDFVFYAPR.L "sp|P15311|EZRI_HUMAN,sp|P26038|MOES_HUMAN,sp|P35241|RADI_HUMAN,tr|A0A2R8Y5S7|A0A2R8Y5S7_HUMAN,tr|E7EQR4|E7EQR4_HUMAN,tr|A0A2R8Y7M3|A0A2R8Y7M3_HUMAN" 6 1181.5869 0.59 5701 17971 2 1181.588591 591.8007 Ezrin OS=Homo sapiens OX=9606 GN=EZR PE=1 SV=4 5.88 3498.2 - 969259 - - - 1.393 - 2.062 0.482 - 423.6 1 2 0 0.0016 10 0 0 0 2.95E+07 5.01E+07 - - - 4.6205 0.9993 221125_WJC_METTL3_EV_vs_WT_F01.17972.17972.2 0.00213 16-Sep K.LYMVLITTK.N "sp|P48444|COPD_HUMAN,tr|B0YIW6|B0YIW6_HUMAN,tr|Q6P1Q5|Q6P1Q5_HUMAN" 3 1080.6253 0.99 5702 17972 2 1080.623623 541.3199 Coatomer subunit delta OS=Homo sapiens OX=9606 GN=ARCN1 PE=1 SV=1 8.59 3498.4 - 429109 - - - -1.5556 - 1.761 0.338 - 189.3 1 2 0 -0.0017 9 0 0 0 1.87E+07 1.90E+07 - - - 3.1741 0.9964 221125_WJC_METTL3_EV_vs_WT_F01.17973.17973.2 0.441 12-Jun R.NYLSIFR.K sp|P07384|CAN1_HUMAN 1 911.4865 12.16 5703 17973 2 911.486325 456.7505 Calpain-1 catalytic subunit OS=Homo sapiens OX=9606 GN=CAPN1 PE=1 SV=1 8.75 3498.5 - 293955 - - - -0.1942 - 1.284 0.204 - 126.3 1 2 0 -0.0002 7 0 0 0 5.79E+07 4.76E+06 - - - 1.3398 0.9968 221125_WJC_METTL3_EV_vs_WT_F01.17974.17974.2 0.00045 22-Jul K.LFVTNDAATILR[166.11].E "sp|P50990|TCPQ_HUMAN,tr|H7C4C8|H7C4C8_HUMAN" 2 1342.7484 0.37 5704 17974 2 1342.753397 672.3815 T-complex protein 1 subunit theta OS=Homo sapiens OX=9606 GN=CCT8 PE=1 SV=4 5.84 3498.6 - 268044 - - - 3.7058 - 1.706 0.373 - 155.4 1 2 0 0.005 12 0 0 0 9.37E+08 2.51E+09 - - - 3.1999 0.9989 221125_WJC_METTL3_EV_vs_WT_F01.17981.17981.2 0.285 14-Aug R.EMVLEIIR[166.11].E "sp|Q96I24|FUBP3_HUMAN,sp|Q96AE4|FUBP1_HUMAN,tr|E9PEB5|E9PEB5_HUMAN" 3 1011.5662 2.12 5709 17981 2 1011.566384 506.7904 Far upstream element-binding protein 3 OS=Homo sapiens OX=9606 GN=FUBP3 PE=1 SV=2 4.53 3499.4 - 8.35E+06 - - - 0.1592 - 1.774 0.21 - 406.8 1 2 0 0.0002 8 0 0 0 1.89E+09 8.91E+08 - - - 2.3209 0.9901 221125_WJC_METTL3_EV_vs_WT_F01.17982.17982.2 0.435 16-Aug K.ILLITEDLK.N sp|Q08752|PPID_HUMAN 1 1056.6431 2.2 5710 17982 2 1056.64357 529.3288 Peptidyl-prolyl cis-trans isomerase D OS=Homo sapiens OX=9606 GN=PPID PE=1 SV=3 4.37 3499.5 - 2.40E+06 - - - 0.4798 - 1.563 0.047 - 179.5 1 2 0 0.0005 9 0 0 0 7.46E+07 3.39E+07 - - - 0.68 0.9998 221125_WJC_METTL3_EV_vs_WT_F01.17983.17983.2 2.66E-06 20-Nov K.FGEPVLAGFAR.S sp|O15067|PUR4_HUMAN 1 1162.6135 0.55 5711 17983 2 1162.614069 582.314 Phosphoribosylformylglycinamidine synthase OS=Homo sapiens OX=9606 GN=PFAS PE=1 SV=4 6 3499.6 - 1.32E+06 - - - 0.4946 - 2.101 0.467 - 537.8 1 2 0 0.0006 11 0 0 0 3.58E+07 6.47E+07 - - - 4.4985 0.9893 221125_WJC_METTL3_EV_vs_WT_F01.17984.17984.2 0.3 12-Jun R.EIFITFR[166.11].V sp|Q96EY1|DNJA3_HUMAN 1 934.5152 1.02 5712 17984 2 934.514899 468.2649 "DnaJ homolog subfamily A member 3, mitochondrial OS=Homo sapiens OX=9606 GN=DNAJA3 PE=1 SV=2" 6.1 3499.7 - 1.12E+06 - - - -0.2932 - 1.282 0.101 - 170.6 1 2 0 -0.0003 7 0 0 0 2.41E+07 2.36E+07 - - - 0.574 0.9998 221125_WJC_METTL3_EV_vs_WT_F01.17993.17993.2 0.000103 28-Aug R.IITGPAPVLPPAALR[166.11].T "sp|Q96PU8|QKI_HUMAN,tr|H0YG47|H0YG47_HUMAN,tr|H0YGD6|H0YGD6_HUMAN" 3 1494.9162 1.63 5721 17993 2 1494.915426 748.4654 Protein quaking OS=Homo sapiens OX=9606 GN=QKI PE=1 SV=1 9.75 3500.8 - 162021 - - - -0.4877 - 1.789 0.483 - 138.7 1 2 0 -0.0007 15 0 0 0 1.07E+07 6.57E+06 - - - 4.0382 0.9993 221125_WJC_METTL3_EV_vs_WT_F01.17996.17996.2 0.0769 16-Sep K.ILLITEDLK[136.11].N sp|Q08752|PPID_HUMAN 1 1064.6573 2.2 5722 17996 2 1064.657889 533.3359 Peptidyl-prolyl cis-trans isomerase D OS=Homo sapiens OX=9606 GN=PPID PE=1 SV=3 4.37 3501.2 - 2.67E+06 - - - 0.588 - 1.922 0.249 - 243.9 1 2 0 0.0006 9 0 0 0 7.46E+07 3.39E+07 - - - 2.7701 0.9997 221125_WJC_METTL3_EV_vs_WT_F01.17998.17998.2 0.00599 20-Nov K.LALDVEIATYR.K "sp|P48668|K2C6C_HUMAN,sp|Q01546|K22O_HUMAN,sp|P12035|K2C3_HUMAN,sp|P04259|K2C6B_HUMAN,sp|P13647|K2C5_HUMAN,sp|P35908|K22E_HUMAN,sp|O95678|K2C75_HUMAN,sp|Q5XKE5|K2C79_HUMAN,sp|P02538|K2C6A_HUMAN,tr|H0YI76|H0YI76_HUMAN,tr|H0YID6|H0YID6_HUMAN" 11 1262.6871 135.98 5724 17998 2 1262.686176 632.3508 "Keratin, type II cytoskeletal 6C OS=Homo sapiens OX=9606 GN=KRT6C PE=1 SV=3" 4.37 3501.4 - 1.74E+06 - - - -0.6946 - 2.446 0.301 - 475.2 1 2 0 -0.0009 11 0 0 0 8.64E+08 6.35E+06 - - - 3.6836 0.9999 221125_WJC_METTL3_EV_vs_WT_F01.18000.18000.2 2.63E-06 14/26 K.VLIPSYAAGSIIGK.G "sp|P51513|NOVA1_HUMAN,sp|Q9UNW9|NOVA2_HUMAN,tr|F8VWX1|F8VWX1_HUMAN,tr|F8W659|F8W659_HUMAN,tr|J3KQU3|J3KQU3_HUMAN,tr|F8VYI3|F8VYI3_HUMAN,tr|A0A6Q8PFC2|A0A6Q8PFC2_HUMAN,tr|I3L2B5|I3L2B5_HUMAN" 8 1387.8075 2.14 5726 18000 2 1387.805551 694.911 RNA-binding protein Nova-1 OS=Homo sapiens OX=9606 GN=NOVA1 PE=1 SV=2 8.56 3501.6 - 1.44E+06 - - - -1.4058 - 2.202 0.58 - 490.3 1 2 0 -0.002 14 0 0 0 1.61E+07 7.50E+06 - - - 5.3051 0.9902 221125_WJC_METTL3_EV_vs_WT_F01.18001.18001.2 0.00673 22-Nov L.PLIPIVVEQTGR.G sp|Q16740|CLPP_HUMAN 1 1320.7765 1.03 5727 18001 2 1320.775727 661.3955 "ATP-dependent Clp protease proteolytic subunit, mitochondrial OS=Homo sapiens OX=9606 GN=CLPP PE=1 SV=1" 6.43 3501.7 - 1.28E+06 - - - -0.6125 - 2.038 0.477 - 284.7 1 1 0 -0.0008 12 0 0 0 1.39E+07 1.34E+07 - - - 4.4372 0.9892 221125_WJC_METTL3_EV_vs_WT_F01.18002.18002.2 8.53E-05 20-Dec R.LLDLVVQPVPR[166.11].P sp|Q8WYP5|ELYS_HUMAN 1 1257.7684 1.12 5728 18002 2 1257.76657 629.8915 Protein ELYS OS=Homo sapiens OX=9606 GN=AHCTF1 PE=1 SV=3 5.84 3501.8 - 1.13E+06 - - - -1.4772 - 2.526 0.452 - 737 1 1 0 -0.0019 11 0 0 0 2.13E+07 1.91E+07 - - - 4.8857 0.9998 221125_WJC_METTL3_EV_vs_WT_F01.18004.18004.2 2.35E-05 22-Oct K.LIVDPALDPALR.R "sp|O15047|SET1A_HUMAN,tr|A0A804HLA6|A0A804HLA6_HUMAN,tr|C9J2Z9|C9J2Z9_HUMAN" 3 1291.75 1.43 5730 18004 2 1291.748618 646.8823 Histone-lysine N-methyltransferase SETD1A OS=Homo sapiens OX=9606 GN=SETD1A PE=1 SV=3 4.21 3502 - 914864 - - - -1.0598 - 2.104 0.444 - 269.7 1 2 0 -0.0014 12 0 0 0 7.25E+07 5.07E+07 - - - 4.2771 0.9999 221125_WJC_METTL3_EV_vs_WT_F01.18006.18006.2 8.20E-05 20-Oct K.VMVTNVTSLLK.T "sp|Q9Y4G6|TLN2_HUMAN,sp|Q9Y490|TLN1_HUMAN,tr|A0A1B0GVU7|A0A1B0GVU7_HUMAN,tr|H0YMT1|H0YMT1_HUMAN" 4 1203.6897 0.38 5732 18006 2 1203.689587 602.8521 Talin-2 OS=Homo sapiens OX=9606 GN=TLN2 PE=1 SV=4 8.72 3502.2 - 732353 - - - -0.0897 - 2.038 0.488 - 311.4 1 2 0 -0.0001 11 0 0 0 9.83E+06 2.58E+07 - - - 4.5714 0.8203 221125_WJC_METTL3_EV_vs_WT_F01.18010.18010.2 0.25 16-Jun K.RAAPDLDVR[166.11].K sp|P01178|NEU1_HUMAN 1 1021.5544 - 5736 18010 2 1021.548346 511.7845 Oxytocin-neurophysin 1 OS=Homo sapiens OX=9606 GN=OXT PE=1 SV=1 5.96 3502.7 - 473410 - - - -5.938 - 1.019 0.257 - 83.4 1 2 0 -0.0061 9 0 0 0 - - - - - 0.9917 0.9999 221125_WJC_METTL3_EV_vs_WT_F01.18013.18013.2 1.86E-06 30-Dec R.IINEPTAAAIAYGLDK[136.11].R "sp|P11021|BIP_HUMAN,sp|P54652|HSP72_HUMAN,sp|P34931|HS71L_HUMAN,sp|P11142|HSP7C_HUMAN,tr|E9PKE3|E9PKE3_HUMAN,tr|E9PN89|E9PN89_HUMAN,tr|A0A7P0TB36|A0A7P0TB36_HUMAN,tr|E9PLF4|E9PLF4_HUMAN,tr|A0A7P0TAI0|A0A7P0TAI0_HUMAN,tr|Q53FA3|Q53FA3_HUMAN,tr|E9PI65|E9PI65_HUMAN" 11 1666.9021 0.25 5737 18013 2 1666.899566 834.4583 Endoplasmic reticulum chaperone BiP OS=Homo sapiens OX=9606 GN=HSPA5 PE=1 SV=2 4.37 3503.1 - 2.51E+06 - - - -1.5424 - 2.493 0.571 - 369.8 1 2 0 -0.0026 16 0 0 0 1.93E+07 7.76E+07 - - - 5.5034 0.9989 221125_WJC_METTL3_EV_vs_WT_F01.18017.18017.2 0.0654 16-Sep R.FEELTNLIR.T "sp|Q99613|EIF3C_HUMAN,sp|B5ME19|EIFCL_HUMAN,tr|H3BPE4|H3BPE4_HUMAN" 3 1133.6081 1.23 5741 18017 2 1133.607029 567.8113 Eukaryotic translation initiation factor 3 subunit C OS=Homo sapiens OX=9606 GN=EIF3C PE=1 SV=1 4.53 3503.4 - 1.58E+06 - - - -0.9218 - 1.836 0.214 - 295.5 1 2 0 -0.001 9 0 0 0 4.52E+07 3.68E+07 - - - 2.3791 0.9998 221125_WJC_METTL3_EV_vs_WT_F01.18018.18018.2 0.00733 22-Dec K.LIVDPALDPALR[166.11].R "sp|O15047|SET1A_HUMAN,tr|A0A804HLA6|A0A804HLA6_HUMAN,tr|C9J2Z9|C9J2Z9_HUMAN" 3 1301.7583 1.43 5742 18018 2 1301.756891 651.8864 Histone-lysine N-methyltransferase SETD1A OS=Homo sapiens OX=9606 GN=SETD1A PE=1 SV=3 4.21 3503.5 - 1.44E+06 - - - -1.0493 - 2.234 0.47 - 446.2 1 2 0 -0.0014 12 0 0 0 7.25E+07 5.07E+07 - - - 4.6269 0.9891 221125_WJC_METTL3_EV_vs_WT_F01.18020.18020.2 0.0751 12-Jun R.TIFSYFK.G sp|Q9UJV9|DDX41_HUMAN 1 904.4695 0.72 5744 18020 2 904.467648 453.242 Probable ATP-dependent RNA helicase DDX41 OS=Homo sapiens OX=9606 GN=DDX41 PE=1 SV=2 8.26 3503.7 - 574474 - - - -1.9979 - 1.135 0.223 - 111.1 1 2 0 -0.0018 7 0 0 0 7.59E+07 1.06E+08 - - - 1.0888 0.9994 221125_WJC_METTL3_EV_vs_WT_F01.18022.18022.3 0.00179 Dec-40 K.LALDVEIATYR.K "sp|P48668|K2C6C_HUMAN,sp|Q01546|K22O_HUMAN,sp|P12035|K2C3_HUMAN,sp|P04259|K2C6B_HUMAN,sp|P13647|K2C5_HUMAN,sp|P35908|K22E_HUMAN,sp|O95678|K2C75_HUMAN,sp|Q5XKE5|K2C79_HUMAN,sp|P02538|K2C6A_HUMAN,tr|H0YI76|H0YI76_HUMAN,tr|H0YID6|H0YID6_HUMAN" 11 1262.6871 51.33 5746 18022 3 1262.685192 421.903 "Keratin, type II cytoskeletal 6C OS=Homo sapiens OX=9606 GN=KRT6C PE=1 SV=3" 4.37 3504 - 389201 - - - -1.4738 - 2.282 0.264 - 238.5 1 2 0 -0.0019 11 0 0 0 2.09E+07 4.07E+05 - - - 3.8267 0.9998 221125_WJC_METTL3_EV_vs_WT_F01.18026.18026.2 6.19E-06 18-Oct K.APDFVFYAPR[166.11].L "sp|P15311|EZRI_HUMAN,sp|P26038|MOES_HUMAN,sp|P35241|RADI_HUMAN,tr|A0A2R8Y5S7|A0A2R8Y5S7_HUMAN,tr|E7EQR4|E7EQR4_HUMAN,tr|A0A2R8Y7M3|A0A2R8Y7M3_HUMAN" 6 1191.5952 0.64 5749 18026 2 1191.593579 596.8049 Ezrin OS=Homo sapiens OX=9606 GN=EZR PE=1 SV=4 5.88 3504.4 - 1.95E+06 - - - -1.3729 - 2.14 0.517 - 483.9 1 2 0 -0.0016 10 0 0 0 3.89E+07 6.11E+07 - - - 4.9827 0.9988 221125_WJC_METTL3_EV_vs_WT_F01.18028.18028.2 0.00392 20-Aug R.LGIPDAVSYIK.K sp|O94874|UFL1_HUMAN 1 1174.6598 1.02 5750 18028 2 1174.662047 588.3372 E3 UFM1-protein ligase 1 OS=Homo sapiens OX=9606 GN=UFL1 PE=1 SV=2 5.83 3504.6 - 2.17E+06 - - - 1.9342 - 1.586 0.361 - 123 1 2 0 0.0023 11 0 0 0 5.39E+07 5.27E+07 - - - 2.9543 0.9999 221125_WJC_METTL3_EV_vs_WT_F01.18029.18029.2 5.04E-05 18-Dec K.IGSDVELLLR[166.11].T sp|Q5U5X0|LYRM7_HUMAN 1 1123.6476 1.19 5751 18029 2 1123.647177 562.8311 Complex III assembly factor LYRM7 OS=Homo sapiens OX=9606 GN=LYRM7 PE=1 SV=1 4.37 3504.7 - 1.39E+06 - - - -0.4156 - 2.577 0.487 - 432.5 1 2 0 -0.0005 10 0 0 0 1.44E+08 1.20E+08 - - - 5.2802 0.9806 221125_WJC_METTL3_EV_vs_WT_F01.18030.18030.2 1.19 14-Jun K.LFNQINIS.- sp|Q92905|CSN5_HUMAN 1 947.5076 - 5752 18030 2 947.507986 474.7611 COP9 signalosome complex subunit 5 OS=Homo sapiens OX=9606 GN=COPS5 PE=1 SV=4 5.52 3504.8 - 1.27E+06 - - - 0.3736 - 1.096 0.121 - 73.2 1 2 0 0.0004 8 0 0 0 - - - - - 0.2111 0.9986 221125_WJC_METTL3_EV_vs_WT_F01.18038.18038.2 0.0315 20-Oct R.LGIPDAVSYIK[136.11].K sp|O94874|UFL1_HUMAN 1 1182.674 2.34 5758 18038 2 1182.674791 592.3443 E3 UFM1-protein ligase 1 OS=Homo sapiens OX=9606 GN=UFL1 PE=1 SV=2 5.83 3505.6 - 1.53E+06 - - - 0.69 - 1.414 0.304 - 187.1 1 2 0 0.0008 11 0 0 0 4.94E+07 2.11E+07 - - - 2.2232 0.9948 221125_WJC_METTL3_EV_vs_WT_F01.18040.18040.2 0.131 16-Jul K.LYMVLITTK[136.11].N "sp|P48444|COPD_HUMAN,tr|B0YIW6|B0YIW6_HUMAN,tr|Q6P1Q5|Q6P1Q5_HUMAN" 3 1088.6395 0.86 5760 18040 2 1088.639831 545.327 Coatomer subunit delta OS=Homo sapiens OX=9606 GN=ARCN1 PE=1 SV=1 8.59 3505.8 - 905115 - - - 0.3004 - 1.247 0.192 - 137.3 1 2 0 0.0003 9 0 0 0 1.61E+07 1.87E+07 - - - 1.0976 0.9999 221125_WJC_METTL3_EV_vs_WT_F01.18044.18044.2 1.02E-06 18-Oct K.FYALDPSFPR.M sp|Q08J23|NSUN2_HUMAN 1 1211.5975 0.95 5762 18044 2 1211.597272 606.806 RNA cytosine C(5)-methyltransferase NSUN2 OS=Homo sapiens OX=9606 GN=NSUN2 PE=1 SV=2 5.84 3506.4 - 1.84E+06 - - - -0.1956 - 2.015 0.592 - 298.7 1 2 0 -0.0002 10 0 0 0 4.52E+07 4.76E+07 - - - 5.3691 0.9993 221125_WJC_METTL3_EV_vs_WT_F01.18045.18045.2 0.0181 14-Aug K.AFSIDIIR[166.11].H "sp|Q9UPN3|MACF1_HUMAN,tr|A0A804HL78|A0A804HL78_HUMAN,tr|H3BQK9|H3BQK9_HUMAN,tr|A0A7P0MQR8|A0A7P0MQR8_HUMAN,tr|H0Y390|H0Y390_HUMAN,tr|H3BPE1|H3BPE1_HUMAN,tr|A0A590UJG2|A0A590UJG2_HUMAN" 7 943.5366 1.53 5763 18045 2 943.536526 472.7756 "Microtubule-actin cross-linking factor 1, isoforms 1\2\3\5 OS=Homo sapiens OX=9606 GN=MACF1 PE=1 SV=4" 5.88 3506.5 - 689172 - - - -0.1176 - 1.635 0.287 - 214.1 1 2 0 -0.0001 8 0 0 0 1.61E+07 1.05E+07 - - - 2.6435 0.8224 221125_WJC_METTL3_EV_vs_WT_F01.18047.18047.2 0.329 24-Jul K.ITTVFSHAQTVVL.C "sp|Q71UM5|RS27L_HUMAN,sp|P42677|RS27_HUMAN,tr|H0YMV8|H0YMV8_HUMAN,tr|C9J1C5|C9J1C5_HUMAN,tr|C9JLI6|C9JLI6_HUMAN" 5 1414.782 - 5765 18047 2 1414.782934 708.3983 40S ribosomal protein S27-like OS=Homo sapiens OX=9606 GN=RPS27L PE=1 SV=3 6.74 3506.7 - 597756 - - - 0.6489 - 1.254 0.247 - 148.4 1 1 0 0.0009 13 0 0 0 - - - - - 1.446 0.9996 221125_WJC_METTL3_EV_vs_WT_F01.18052.18052.2 0.00302 18-Jun K.FYALDPSFPR[166.11].M sp|Q08J23|NSUN2_HUMAN 1 1221.6058 0.95 5769 18052 2 1221.606299 611.8102 RNA cytosine C(5)-methyltransferase NSUN2 OS=Homo sapiens OX=9606 GN=NSUN2 PE=1 SV=2 5.84 3507.3 - 1.59E+06 - - - 0.4257 - 1.583 0.398 - 100.5 1 2 0 0.0005 10 0 0 0 4.51E+07 4.77E+07 - - - 3.2626 0.9999 221125_WJC_METTL3_EV_vs_WT_F01.18054.18054.2 0.000145 18-Oct K.IGSDVELLLR.T sp|Q5U5X0|LYRM7_HUMAN 1 1113.6394 1.17 5770 18054 2 1113.639078 557.827 Complex III assembly factor LYRM7 OS=Homo sapiens OX=9606 GN=LYRM7 PE=1 SV=1 4.37 3507.5 - 7.97E+06 - - - -0.2658 - 2.121 0.52 - 274.9 1 2 0 -0.0003 10 0 0 0 1.44E+08 1.23E+08 - - - 4.9804 0.9998 221125_WJC_METTL3_EV_vs_WT_F01.18056.18056.2 0.00176 16-Sep R.LYSVSYLLK.D "sp|P21333|FLNA_HUMAN,tr|A0A7P0NMY4|A0A7P0NMY4_HUMAN,tr|Q60FE5|Q60FE5_HUMAN" 3 1084.6168 0.82 5772 18056 2 1084.615899 543.3157 Filamin-A OS=Homo sapiens OX=9606 GN=FLNA PE=1 SV=4 8.5 3507.6 - 1.55E+06 - - - -0.875 - 1.816 0.471 - 187.2 1 2 0 -0.0009 9 0 0 0 3.32E+07 4.06E+07 - - - 4.2456 0.9999 221125_WJC_METTL3_EV_vs_WT_F01.18057.18057.2 0.000468 18-Dec K.TLVQILTEPR.N sp|O76031|CLPX_HUMAN 1 1168.6816 1.5 5773 18057 2 1168.682741 585.3481 "ATP-dependent Clp protease ATP-binding subunit clpX-like, mitochondrial OS=Homo sapiens OX=9606 GN=CLPX PE=1 SV=2" 5.66 3507.8 - 860376 - - - 0.9994 - 2.36 0.489 - 459.1 1 2 0 0.0012 10 0 0 0 4.55E+07 3.03E+07 - - - 5.0492 0.94 221125_WJC_METTL3_EV_vs_WT_F01.18060.18060.2 1.62 18-Apr K.FQMAYSNLLR.A sp|P37108|SRP14_HUMAN 1 1241.6227 0.86 5775 18060 2 1241.620166 621.8186 Signal recognition particle 14 kDa protein OS=Homo sapiens OX=9606 GN=SRP14 PE=1 SV=2 8.75 3508.1 - 1.30E+06 - - - -2.0232 - 0.99 0.19 - 43.3 12 2 0 -0.0025 10 0 0 0 4.02E+07 4.68E+07 - - - -0.0666 0.9996 221125_WJC_METTL3_EV_vs_WT_F01.18062.18062.2 0.00191 16-Aug R.ILFLDPSGK.V sp|O95881|TXD12_HUMAN 1 988.5593 1.25 5776 18062 2 988.55966 495.2869 Thioredoxin domain-containing protein 12 OS=Homo sapiens OX=9606 GN=TXNDC12 PE=1 SV=1 5.84 3508.3 - 7.34E+07 - - - 0.3308 - 1.638 0.401 - 209.9 1 2 0 0.0003 9 0 0 0 1.79E+09 1.44E+09 - - - 3.4303 0.9995 221125_WJC_METTL3_EV_vs_WT_F01.18063.18063.2 0.000739 20-Oct K.LDPGLIMEQVK.V sp|Q9Y5L4|TIM13_HUMAN 1 1241.669 1.67 5777 18063 2 1241.670825 621.8418 Mitochondrial import inner membrane translocase subunit Tim13 OS=Homo sapiens OX=9606 GN=TIMM13 PE=1 SV=1 4.37 3508.3 - 1.59E+06 - - - 1.502 - 1.822 0.414 - 227.6 1 2 0 0.0019 11 0 0 0 4.47E+07 2.68E+07 - - - 3.7212 1 221125_WJC_METTL3_EV_vs_WT_F01.18064.18064.2 2.89E-08 26-Dec K.FYGPEGPYGVFAGR.D sp|O00264|PGRC1_HUMAN 1 1515.7147 1.3 5778 18064 2 1515.71332 758.8646 Membrane-associated progesterone receptor component 1 OS=Homo sapiens OX=9606 GN=PGRMC1 PE=1 SV=3 6 3508.5 - 863403 - - - -0.8867 - 2.28 0.656 - 456.9 1 2 0 -0.0013 14 0 0 0 2.37E+08 1.83E+08 - - - 5.954 0.9892 221125_WJC_METTL3_EV_vs_WT_F01.18066.18066.2 0.000358 18-Oct R.ADPALC[160.03]FLER[166.11].V "sp|Q9P2D1|CHD7_HUMAN,sp|Q3L8U1|CHD9_HUMAN,tr|H3BTW3|H3BTW3_HUMAN,tr|A0A087WU44|A0A087WU44_HUMAN" 4 1200.5837 2 5780 18066 2 1200.590883 601.2991 Chromodomain-helicase-DNA-binding protein 7 OS=Homo sapiens OX=9606 GN=CHD7 PE=1 SV=3 4.37 3508.7 - 347826 - - - 6.0129 - 1.801 0.404 - 327.5 1 2 0 0.0072 10 0 0 0 9.21E+06 4.60E+06 - - - 3.6649 0.9971 221125_WJC_METTL3_EV_vs_WT_F01.18069.18069.2 0.243 18-Jul K.FLALYLHGAA.- "sp|Q9BZE1|RM37_HUMAN,tr|A6NHR2|A6NHR2_HUMAN" 2 1074.5862 - 5781 18069 2 1074.586866 538.3004 "39S ribosomal protein L37, mitochondrial OS=Homo sapiens OX=9606 GN=MRPL37 PE=1 SV=2" 6.74 3509.1 - 2.33E+06 - - - 0.6049 - 1.337 0.236 - 98.8 1 2 0 0.0006 10 0 0 0 - - - - - 1.5946 0.9999 221125_WJC_METTL3_EV_vs_WT_F01.18071.18071.2 1.94E-05 20-Dec R.MLDMGFEPQIR[166.11].R "sp|O00571|DDX3X_HUMAN,sp|O15523|DDX3Y_HUMAN,sp|Q92841|DDX17_HUMAN,sp|P17844|DDX5_HUMAN,tr|A0A2R8YFR4|A0A2R8YFR4_HUMAN,tr|A0A2R8YCW1|A0A2R8YCW1_HUMAN,tr|A0A7I2V5F5|A0A7I2V5F5_HUMAN,tr|A0A2R8YDH3|A0A2R8YDH3_HUMAN,tr|A0A2R8YDT5|A0A2R8YDT5_HUMAN,tr|A0A2R8Y645|A0A2R8Y645_HUMAN,tr|A0A2R8YF78|A0A2R8YF78_HUMAN,tr|J3KRZ1|J3KRZ1_HUMAN,tr|A0A0D9SFB3|A0A0D9SFB3_HUMAN,tr|A0A2R8YFS5|A0A2R8YFS5_HUMAN,tr|J3QSF1|J3QSF1_HUMAN,tr|A0A7I2V507|A0A7I2V507_HUMAN,tr|A0A5H1ZRQ2|A0A5H1ZRQ2_HUMAN,tr|A0A0D9SF53|A0A0D9SF53_HUMAN,tr|J3KTA4|J3KTA4_HUMAN,tr|A0A0G2JLI4|A0A0G2JLI4_HUMAN,tr|A0A1X7SBZ2|A0A1X7SBZ2_HUMAN,tr|A0A2R8Y5G6|A0A2R8Y5G6_HUMAN,tr|A0A2R8Y7T2|A0A2R8Y7T2_HUMAN,tr|A0A0D9SG12|A0A0D9SG12_HUMAN,tr|A0A7I2V2S0|A0A7I2V2S0_HUMAN,tr|F6S8Q4|F6S8Q4_HUMAN,tr|A0A2U3TZJ9|A0A2U3TZJ9_HUMAN,tr|A0A2R8Y4A4|A0A2R8Y4A4_HUMAN" 28 1345.6398 1.3 5783 18071 2 1345.639547 673.8272 ATP-dependent RNA helicase DDX3X OS=Homo sapiens OX=9606 GN=DDX3X PE=1 SV=3 4.37 3509.3 - 1.03E+06 - - - -0.1865 - 2.311 0.505 - 561.1 1 2 0 -0.0003 11 0 0 0 5.77E+08 4.43E+08 - - - 5.037 0.9999 221125_WJC_METTL3_EV_vs_WT_F01.18072.18072.2 0.000379 20-Oct R.MLDMGFEPQIR.R "sp|O00571|DDX3X_HUMAN,sp|O15523|DDX3Y_HUMAN,sp|Q92841|DDX17_HUMAN,sp|P17844|DDX5_HUMAN,tr|A0A2R8YFR4|A0A2R8YFR4_HUMAN,tr|A0A2R8YCW1|A0A2R8YCW1_HUMAN,tr|A0A7I2V5F5|A0A7I2V5F5_HUMAN,tr|A0A2R8YDH3|A0A2R8YDH3_HUMAN,tr|A0A2R8YDT5|A0A2R8YDT5_HUMAN,tr|A0A2R8Y645|A0A2R8Y645_HUMAN,tr|A0A2R8YF78|A0A2R8YF78_HUMAN,tr|J3KRZ1|J3KRZ1_HUMAN,tr|A0A0D9SFB3|A0A0D9SFB3_HUMAN,tr|A0A2R8YFS5|A0A2R8YFS5_HUMAN,tr|J3QSF1|J3QSF1_HUMAN,tr|A0A7I2V507|A0A7I2V507_HUMAN,tr|A0A5H1ZRQ2|A0A5H1ZRQ2_HUMAN,tr|A0A0D9SF53|A0A0D9SF53_HUMAN,tr|J3KTA4|J3KTA4_HUMAN,tr|A0A0G2JLI4|A0A0G2JLI4_HUMAN,tr|A0A1X7SBZ2|A0A1X7SBZ2_HUMAN,tr|A0A2R8Y5G6|A0A2R8Y5G6_HUMAN,tr|A0A2R8Y7T2|A0A2R8Y7T2_HUMAN,tr|A0A0D9SG12|A0A0D9SG12_HUMAN,tr|A0A7I2V2S0|A0A7I2V2S0_HUMAN,tr|F6S8Q4|F6S8Q4_HUMAN,tr|A0A2U3TZJ9|A0A2U3TZJ9_HUMAN,tr|A0A2R8Y4A4|A0A2R8Y4A4_HUMAN" 28 1335.6315 1.3 5784 18072 2 1335.630986 668.823 ATP-dependent RNA helicase DDX3X OS=Homo sapiens OX=9606 GN=DDX3X PE=1 SV=3 4.37 3509.4 - 866128 - - - -0.4058 - 2.011 0.492 - 400.1 1 2 0 -0.0005 11 0 0 0 5.77E+08 4.43E+08 - - - 4.5647 0.999 221125_WJC_METTL3_EV_vs_WT_F01.18074.18074.2 0.00246 16-Oct K.SGFEGMFIR.K sp|P49792|RBP2_HUMAN 1 1042.4906 0.56 5786 18074 2 1042.492616 522.2526 E3 SUMO-protein ligase RanBP2 OS=Homo sapiens OX=9606 GN=RANBP2 PE=1 SV=2 5.72 3509.7 - 648773 - - - 1.9329 - 1.574 0.38 - 260.9 1 2 0 0.002 9 0 0 0 1.21E+07 2.18E+07 - - - 3.1594 0.9998 221125_WJC_METTL3_EV_vs_WT_F01.18075.18075.2 0.0024 12-Sep K.C[160.03]ALDFFR[166.11].Q sp|P51970|NDUA8_HUMAN 1 937.4355 1.16 5787 18075 2 937.434741 469.725 NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 8 OS=Homo sapiens OX=9606 GN=NDUFA8 PE=1 SV=3 5.83 3509.8 - 546803 - - - -0.8555 - 1.736 0.448 - 255.7 1 2 0 -0.0008 7 0 0 0 5.86E+07 5.05E+07 - - - 4.0974 0.9995 221125_WJC_METTL3_EV_vs_WT_F01.18076.18076.2 0.0477 16-Oct M.AILFAVVAR.G "sp|P51809|VAMP7_HUMAN,tr|E5RH06|E5RH06_HUMAN" 2 958.5964 0.14 5788 18076 2 958.597179 480.3055 Vesicle-associated membrane protein 7 OS=Homo sapiens OX=9606 GN=VAMP7 PE=1 SV=3 9.79 3509.9 - 485330 - - - 0.8262 - 2.081 0.287 - 311.5 1 2 0 0.0008 9 0 0 0 9.61E+06 6.94E+07 - - - 3.2807 0.9998 221125_WJC_METTL3_EV_vs_WT_F01.18079.18079.2 3.77E-06 13/26 K.FYGPEGPYGVFAGR[166.11].D sp|O00264|PGRC1_HUMAN 1 1525.7229 1.3 5789 18079 2 1525.722384 763.8687 Membrane-associated progesterone receptor component 1 OS=Homo sapiens OX=9606 GN=PGRMC1 PE=1 SV=3 6 3510.4 - 2.34E+06 - - - -0.3605 - 1.921 0.512 - 200.1 1 2 0 -0.0006 14 0 0 0 2.37E+08 1.83E+08 - - - 4.4607 0.9953 221125_WJC_METTL3_EV_vs_WT_F01.18080.18080.2 0.129 12-Jun R.WMAQYID.- "sp|Q9Y6B6|SAR1B_HUMAN,tr|Q9H029|Q9H029_HUMAN" 2 925.4004 - 5790 18080 2 925.400378 463.7075 GTP-binding protein SAR1b OS=Homo sapiens OX=9606 GN=SAR1B PE=1 SV=1 4.3 3510.5 - 1.62E+06 - - - -0.0119 - 1.037 0.269 - 83.3 1 2 0 0 7 0 0 0 - - - - - 1.143 1 221125_WJC_METTL3_EV_vs_WT_F01.18081.18081.2 2.70E-06 13/22 K.SLNNQFASFIDK.V sp|P04264|K2C1_HUMAN 1 1382.683 152.11 5791 18081 2 1382.67807 692.3488 "Keratin, type II cytoskeletal 1 OS=Homo sapiens OX=9606 GN=KRT1 PE=1 SV=6" 5.55 3510.6 - 1.44E+06 - - - -3.5872 - 2.577 0.57 - 555.6 1 2 0 -0.005 12 0 0 0 2.58E+07 1.69E+05 - - - 5.7402 0.9968 221125_WJC_METTL3_EV_vs_WT_F01.18082.18082.2 0.142 14-Aug K.SIGDIFLK[136.11].Y "sp|Q9H8V3|ECT2_HUMAN,tr|H7C3G1|H7C3G1_HUMAN" 2 899.5208 1.19 5792 18082 2 899.521446 450.7677 Protein ECT2 OS=Homo sapiens OX=9606 GN=ECT2 PE=1 SV=4 5.55 3510.7 - 1.32E+06 - - - 0.7526 - 1.296 0.234 - 157.4 1 2 0 0.0007 8 0 0 0 1.91E+07 1.61E+07 - - - 1.5511 0.998 221125_WJC_METTL3_EV_vs_WT_F01.18085.18085.2 0.224 16-Oct M.AILFAVVAR[166.11].G "sp|P51809|VAMP7_HUMAN,tr|E5RH06|E5RH06_HUMAN" 2 968.6047 0.08 5795 18085 2 968.60523 485.3096 Vesicle-associated membrane protein 7 OS=Homo sapiens OX=9606 GN=VAMP7 PE=1 SV=3 9.79 3510.9 - 787073 - - - 0.5916 - 1.869 0.138 - 322.1 1 2 0 0.0006 9 0 0 0 1.18E+07 1.44E+08 - - - 1.8694 0.8133 221125_WJC_METTL3_EV_vs_WT_F01.18086.18086.2 17.2 12-May K.LIPFLEK.L sp|Q05D32|CTSL2_HUMAN 1 858.5215 1.44 5796 18086 2 858.520704 430.268 CTD small phosphatase-like protein 2 OS=Homo sapiens OX=9606 GN=CTDSPL2 PE=1 SV=2 6 3511.1 - 735256 - - - -0.9167 - 1.036 0.026 - 51.3 22 2 0 -0.0008 7 0 0 0 1.33E+07 9.25E+06 - - - -1.2548 0.9144 221125_WJC_METTL3_EV_vs_WT_F01.18089.18089.2 0.0361 12-May K.GQYISPF.H "sp|Q15181|IPYR_HUMAN,tr|Q5SQT6|Q5SQT6_HUMAN" 2 810.3912 - 5799 18089 2 810.390974 406.2029 Inorganic pyrophosphatase OS=Homo sapiens OX=9606 GN=PPA1 PE=1 SV=2 5.52 3511.4 - 352002 - - - -0.285 - 1.115 0.353 - 81.9 1 1 0 -0.0002 7 0 0 0 - - - - - 1.9931 0.9997 221125_WJC_METTL3_EV_vs_WT_F01.18093.18093.2 0.00146 16-Nov K.LEVDIPLVK.S "sp|P78344|IF4G2_HUMAN,tr|E9PKF8|E9PKF8_HUMAN,tr|H0Y3P2|H0Y3P2_HUMAN,tr|H0YE22|H0YE22_HUMAN,tr|D3DQV9|D3DQV9_HUMAN" 5 1024.6168 2.36 5801 18093 2 1024.615798 513.3157 Eukaryotic translation initiation factor 4 gamma 2 OS=Homo sapiens OX=9606 GN=EIF4G2 PE=1 SV=1 4.37 3511.9 - 2.69E+06 - - - -1.0248 - 1.845 0.399 - 380.5 1 2 0 -0.001 9 0 0 0 2.52E+08 1.07E+08 - - - 3.7596 0.8933 221125_WJC_METTL3_EV_vs_WT_F01.18094.18094.2 0.216 18-Jul K.SFYPEEVSSM.V "sp|P11142|HSP7C_HUMAN,tr|E9PQQ4|E9PQQ4_HUMAN,tr|E9PKE3|E9PKE3_HUMAN,tr|E9PN89|E9PN89_HUMAN,tr|E9PLF4|E9PLF4_HUMAN,tr|E9PI65|E9PI65_HUMAN,tr|E9PK54|E9PK54_HUMAN,tr|E9PN25|E9PN25_HUMAN,tr|E9PPY6|E9PPY6_HUMAN,tr|E9PQK7|E9PQK7_HUMAN" 10 1174.4852 - 5802 18094 2 1174.485557 588.2499 Heat shock cognate 71 kDa protein OS=Homo sapiens OX=9606 GN=HSPA8 PE=1 SV=1 3.79 3512 - 1.63E+06 - - - 0.2691 - 0.96 0.392 - 132.9 1 1 0 0.0003 10 0 0 0 - - - - - 1.8223 0.9894 221125_WJC_METTL3_EV_vs_WT_F01.18095.18095.2 0.000636 18-Oct R.IPLNPYLNLH.S "tr|E9PAU2|E9PAU2_HUMAN,tr|A0A087WZ13|A0A087WZ13_HUMAN" 2 1192.6604 - 5803 18095 2 1192.660078 597.3375 Ribonucleoprotein PTB-binding 1 OS=Homo sapiens OX=9606 GN=RAVER1 PE=1 SV=1 6.74 3512.1 - 1.88E+06 - - - -0.3069 - 2.041 0.435 - 408.1 1 1 0 -0.0004 10 0 0 0 - - - - - 4.2452 0.9997 221125_WJC_METTL3_EV_vs_WT_F01.18096.18096.2 0.0148 16-Sep K.LEVDIPLVK[136.11].S "sp|P78344|IF4G2_HUMAN,tr|E9PKF8|E9PKF8_HUMAN,tr|H0Y3P2|H0Y3P2_HUMAN,tr|H0YE22|H0YE22_HUMAN,tr|D3DQV9|D3DQV9_HUMAN" 5 1032.631 2.35 5804 18096 2 1032.630871 517.3228 Eukaryotic translation initiation factor 4 gamma 2 OS=Homo sapiens OX=9606 GN=EIF4G2 PE=1 SV=1 4.37 3512.1 - 1.27E+06 - - - -0.1714 - 1.894 0.391 - 227.1 1 2 0 -0.0002 9 0 0 0 2.52E+08 1.07E+08 - - - 3.7766 0.9968 221125_WJC_METTL3_EV_vs_WT_F01.18098.18098.2 0.558 12-Jun R.LFLEFER[166.11].K "sp|O43663|PRC1_HUMAN,sp|Q96I25|SPF45_HUMAN,tr|H0YL53|H0YL53_HUMAN" 3 962.5101 0.4 5806 18098 2 962.511008 482.2623 Protein regulator of cytokinesis 1 OS=Homo sapiens OX=9606 GN=PRC1 PE=1 SV=2 4.53 3512.3 - 869769 - - - 0.9558 - 1.406 0.203 - 111.1 1 2 0 0.0009 7 0 0 0 2.30E+07 5.70E+07 - - - 1.6198 0.9669 221125_WJC_METTL3_EV_vs_WT_F01.18105.18105.2 1.88 14-Jul K.SIGDIFLK.Y "sp|Q9H8V3|ECT2_HUMAN,tr|H7C3G1|H7C3G1_HUMAN" 2 891.5066 1.02 5812 18105 2 891.506497 446.7606 Protein ECT2 OS=Homo sapiens OX=9606 GN=ECT2 PE=1 SV=4 5.55 3513.2 - 1.61E+06 - - - -0.0808 - 0.96 0.123 - 129.1 1 2 0 -0.0001 8 0 0 0 2.03E+07 1.99E+07 - - - -0.1737 0.9999 221125_WJC_METTL3_EV_vs_WT_F01.18108.18108.2 0.00508 20-Dec R.ALDTMNFDVIK[136.11].G "sp|Q13310|PABP4_HUMAN,sp|Q9H361|PABP3_HUMAN,sp|P11940|PABP1_HUMAN,tr|A0A7I2V5W9|A0A7I2V5W9_HUMAN,tr|A0A7I2V649|A0A7I2V649_HUMAN,tr|B1ANR0|B1ANR0_HUMAN,tr|A0A7I2V4L7|A0A7I2V4L7_HUMAN,tr|B1ANR1|B1ANR1_HUMAN,tr|H0YAR2|H0YAR2_HUMAN,tr|E7ERJ7|E7ERJ7_HUMAN,tr|E5RJB9|E5RJB9_HUMAN,tr|A0A7I2YQ88|A0A7I2YQ88_HUMAN,tr|H0YEQ8|H0YEQ8_HUMAN,tr|E5RH24|E5RH24_HUMAN,tr|H0YBN4|H0YBN4_HUMAN,tr|E5RGH3|E5RGH3_HUMAN,tr|A0A087WTT1|A0A087WTT1_HUMAN,tr|A0A7I2YQ90|A0A7I2YQ90_HUMAN,tr|A0A7I2V4N4|A0A7I2V4N4_HUMAN,tr|E7EQV3|E7EQV3_HUMAN" 20 1273.6468 1.31 5814 18108 2 1273.646483 637.8307 Polyadenylate-binding protein 4 OS=Homo sapiens OX=9606 GN=PABPC4 PE=1 SV=1 4.21 3513.5 - 2.16E+06 - - - -0.2285 - 2.456 0.423 - 377 1 2 0 -0.0003 11 0 0 0 2.32E+08 1.77E+08 - - - 4.5959 0.9998 221125_WJC_METTL3_EV_vs_WT_F01.18110.18110.3 0.00308 Aug-40 R.MLDMGFEPQIR[166.11].R "sp|O00571|DDX3X_HUMAN,sp|O15523|DDX3Y_HUMAN,sp|Q92841|DDX17_HUMAN,sp|P17844|DDX5_HUMAN,tr|A0A2R8YFR4|A0A2R8YFR4_HUMAN,tr|A0A2R8YCW1|A0A2R8YCW1_HUMAN,tr|A0A7I2V5F5|A0A7I2V5F5_HUMAN,tr|A0A2R8YDH3|A0A2R8YDH3_HUMAN,tr|A0A2R8YDT5|A0A2R8YDT5_HUMAN,tr|A0A2R8Y645|A0A2R8Y645_HUMAN,tr|A0A2R8YF78|A0A2R8YF78_HUMAN,tr|J3KRZ1|J3KRZ1_HUMAN,tr|A0A0D9SFB3|A0A0D9SFB3_HUMAN,tr|A0A2R8YFS5|A0A2R8YFS5_HUMAN,tr|J3QSF1|J3QSF1_HUMAN,tr|A0A7I2V507|A0A7I2V507_HUMAN,tr|A0A5H1ZRQ2|A0A5H1ZRQ2_HUMAN,tr|A0A0D9SF53|A0A0D9SF53_HUMAN,tr|J3KTA4|J3KTA4_HUMAN,tr|A0A0G2JLI4|A0A0G2JLI4_HUMAN,tr|A0A1X7SBZ2|A0A1X7SBZ2_HUMAN,tr|A0A2R8Y5G6|A0A2R8Y5G6_HUMAN,tr|A0A2R8Y7T2|A0A2R8Y7T2_HUMAN,tr|A0A0D9SG12|A0A0D9SG12_HUMAN,tr|A0A7I2V2S0|A0A7I2V2S0_HUMAN,tr|F6S8Q4|F6S8Q4_HUMAN,tr|A0A2U3TZJ9|A0A2U3TZJ9_HUMAN,tr|A0A2R8Y4A4|A0A2R8Y4A4_HUMAN" 28 1345.6398 1.92 5816 18110 3 1345.640132 449.5539 ATP-dependent RNA helicase DDX3X OS=Homo sapiens OX=9606 GN=DDX3X PE=1 SV=3 4.37 3513.6 - 1.42E+06 - - - 0.2482 - 1.812 0.394 - 90.3 1 2 0 0.0003 11 0 0 0 4.65E+07 2.42E+07 - - - 4.6213 0.9998 221125_WJC_METTL3_EV_vs_WT_F01.18111.18111.2 0.000217 20-Nov K.LDPGLIMEQVK[136.11].V sp|Q9Y5L4|TIM13_HUMAN 1 1249.6832 1.67 5817 18111 2 1249.683618 625.8489 Mitochondrial import inner membrane translocase subunit Tim13 OS=Homo sapiens OX=9606 GN=TIMM13 PE=1 SV=1 4.37 3513.7 - 1.21E+06 - - - 0.3665 - 1.916 0.474 - 455.6 1 2 0 0.0005 11 0 0 0 4.46E+07 2.68E+07 - - - 4.3009 0.9991 221125_WJC_METTL3_EV_vs_WT_F01.18113.18113.2 0.0194 18-Nov R.LGLLGLPAPK.N sp|Q99459|CDC5L_HUMAN 1 977.6274 1.35 5819 18113 2 977.627808 489.821 Cell division cycle 5-like protein OS=Homo sapiens OX=9606 GN=CDC5L PE=1 SV=2 8.75 3513.9 - 549278 - - - 0.4654 - 2.267 0.16 - 237.6 1 2 0 0.0005 10 0 0 0 3.89E+08 2.87E+08 - - - 2.5072 0.9999 221125_WJC_METTL3_EV_vs_WT_F01.18115.18115.2 0.000172 22-Oct K.VIGPEPTGFLLK[136.11].F sp|Q8IUH4|ZDH13_HUMAN 1 1277.7475 1.36 5821 18115 2 1277.747546 639.881 Palmitoyltransferase ZDHHC13 OS=Homo sapiens OX=9606 GN=ZDHHC13 PE=1 SV=3 5.97 3514.2 - 524376 - - - 0.0556 - 2.046 0.497 - 251.4 1 2 0 0.0001 12 0 0 0 1.79E+07 1.32E+07 - - - 4.5954 0.9999 221125_WJC_METTL3_EV_vs_WT_F01.18116.18116.2 4.12E-05 20-Nov K.LVNIYDSMPLR.Y sp|Q9UBQ6|EXTL2_HUMAN 1 1319.6908 1.52 5822 18116 2 1319.689356 660.8527 Exostosin-like 2 OS=Homo sapiens OX=9606 GN=EXTL2 PE=1 SV=1 5.84 3514.3 - 378329 - - - -1.0624 - 2.408 0.505 - 559.6 1 2 0 -0.0014 11 0 0 0 1.55E+07 1.02E+07 - - - 5.1478 0.9999 221125_WJC_METTL3_EV_vs_WT_F01.18117.18117.2 1.58E-05 20-Nov K.LVNIYDSMPLR[166.11].Y sp|Q9UBQ6|EXTL2_HUMAN 1 1329.699 1.52 5823 18117 2 1329.699043 665.8568 Exostosin-like 2 OS=Homo sapiens OX=9606 GN=EXTL2 PE=1 SV=1 5.84 3514.5 - 317019 - - - 0.0113 - 2.343 0.506 - 555.5 1 2 0 0 11 0 0 0 1.55E+07 1.02E+07 - - - 5.0816 0.9999 221125_WJC_METTL3_EV_vs_WT_F01.18121.18121.2 0.000669 28-Dec R.IITGPAPVLPPAALR.T "sp|Q96PU8|QKI_HUMAN,tr|H0YG47|H0YG47_HUMAN,tr|H0YGD6|H0YGD6_HUMAN" 3 1484.9079 3.79 5826 18121 2 1484.906747 743.4612 Protein quaking OS=Homo sapiens OX=9606 GN=QKI PE=1 SV=1 9.75 3515 - 288100 - - - -0.7664 - 2.344 0.531 - 391.5 1 2 0 -0.0011 15 0 0 0 1.23E+07 3.24E+06 - - - 5.0569 0.9999 221125_WJC_METTL3_EV_vs_WT_F01.18123.18123.2 0.00116 20-Oct R.ALDTMNFDVIK.G "sp|Q13310|PABP4_HUMAN,sp|Q9H361|PABP3_HUMAN,sp|P11940|PABP1_HUMAN,tr|A0A7I2V5W9|A0A7I2V5W9_HUMAN,tr|A0A7I2V649|A0A7I2V649_HUMAN,tr|B1ANR0|B1ANR0_HUMAN,tr|A0A7I2V4L7|A0A7I2V4L7_HUMAN,tr|B1ANR1|B1ANR1_HUMAN,tr|H0YAR2|H0YAR2_HUMAN,tr|E7ERJ7|E7ERJ7_HUMAN,tr|E5RJB9|E5RJB9_HUMAN,tr|A0A7I2YQ88|A0A7I2YQ88_HUMAN,tr|H0YEQ8|H0YEQ8_HUMAN,tr|E5RH24|E5RH24_HUMAN,tr|H0YBN4|H0YBN4_HUMAN,tr|E5RGH3|E5RGH3_HUMAN,tr|A0A087WTT1|A0A087WTT1_HUMAN,tr|A0A7I2YQ90|A0A7I2YQ90_HUMAN,tr|A0A7I2V4N4|A0A7I2V4N4_HUMAN,tr|E7EQV3|E7EQV3_HUMAN" 20 1265.6326 1.31 5827 18123 2 1265.633053 633.8236 Polyadenylate-binding protein 4 OS=Homo sapiens OX=9606 GN=PABPC4 PE=1 SV=1 4.21 3515.2 - 7.02E+06 - - - 0.3785 - 2.355 0.449 - 235.1 1 2 0 0.0005 11 0 0 0 2.32E+08 1.77E+08 - - - 4.6743 0.9998 221125_WJC_METTL3_EV_vs_WT_F01.18125.18125.2 0.000646 18-Sep R.VLLMELEEAR[166.11].G sp|P12270|TPR_HUMAN 1 1211.6459 2.27 5829 18125 2 1211.646192 606.8302 Nucleoprotein TPR OS=Homo sapiens OX=9606 GN=TPR PE=1 SV=3 4.25 3515.3 - 1.77E+06 - - - 0.2162 - 2.023 0.383 - 367.5 1 2 0 0.0003 10 0 0 0 1.34E+08 5.90E+07 - - - 3.8365 0.9996 221125_WJC_METTL3_EV_vs_WT_F01.18127.18127.2 0.000778 16-Oct R.ELGELIPLR[166.11].Q "sp|Q14980|NUMA1_HUMAN,tr|A0A087WY61|A0A087WY61_HUMAN,tr|H0YFY6|H0YFY6_HUMAN,tr|K4DIE0|K4DIE0_HUMAN" 4 1048.6156 1.11 5831 18127 2 1048.61623 525.3151 Nuclear mitotic apparatus protein 1 OS=Homo sapiens OX=9606 GN=NUMA1 PE=1 SV=2 4.53 3515.5 - 610713 - - - 0.5855 - 1.792 0.353 - 287.3 1 2 0 0.0006 9 0 0 0 3.14E+07 2.84E+07 - - - 3.3357 0.9934 221125_WJC_METTL3_EV_vs_WT_F01.18142.18142.2 0.212 14-Jun K.DLYSALIK.L sp|O75844|FACE1_HUMAN 1 921.5171 0.96 5842 18142 2 921.516072 461.7658 CAAX prenyl protease 1 homolog OS=Homo sapiens OX=9606 GN=ZMPSTE24 PE=1 SV=2 5.83 3517.5 - 2.56E+06 - - - -1.1524 - 1.276 0.213 - 94.8 4 2 0 -0.0011 8 0 0 0 3.67E+07 3.82E+07 - - - 1.08 0.9987 221125_WJC_METTL3_EV_vs_WT_F01.18144.18144.2 0.0424 16-Sep K.LSDGVAVLK[136.11].V "sp|P10809|CH60_HUMAN,tr|A0A7I2V2X6|A0A7I2V2X6_HUMAN,tr|A0A7I2YQK6|A0A7I2YQK6_HUMAN,tr|A0A7I2V599|A0A7I2V599_HUMAN" 4 908.5422 1.54 5844 18144 2 908.540634 455.2784 "60 kDa heat shock protein, mitochondrial OS=Homo sapiens OX=9606 GN=HSPD1 PE=1 SV=2" 5.84 3517.7 - 793604 - - - -1.76 - 1.774 0.269 - 143.2 1 2 0 -0.0016 9 0 0 0 3.13E+07 2.03E+07 - - - 2.6857 0.9333 221125_WJC_METTL3_EV_vs_WT_F01.18151.18151.2 0.0041 16-Jul K.LLQDFFNGR.D "sp|P0DMV8|HS71A_HUMAN,sp|P0DMV9|HS71B_HUMAN,tr|V9GZ37|V9GZ37_HUMAN,tr|A0A0G2JIW1|A0A0G2JIW1_HUMAN" 4 1108.5665 0.15 5849 18151 2 1108.559292 555.2905 Heat shock 70 kDa protein 1A OS=Homo sapiens OX=9606 GN=HSPA1A PE=1 SV=1 5.84 3518.6 - 1.44E+07 - - - -6.5409 - 1.629 0.232 - 129 1 2 0 -0.0073 9 0 0 0 5.50E+08 3.61E+09 - - - 2.164 0.9398 221125_WJC_METTL3_EV_vs_WT_F01.18152.18152.2 0.164 12-Jun K.DFISVLR[166.11].G sp|Q9Y3B9|RRP15_HUMAN 1 858.4839 1.03 5850 18152 2 858.485198 430.2492 RRP15-like protein OS=Homo sapiens OX=9606 GN=RRP15 PE=1 SV=2 5.84 3518.7 - 1.01E+06 - - - 1.5434 - 1.259 0.003 - 148.6 1 2 0 0.0013 7 0 0 0 4.24E+07 4.13E+07 - - - -0.2075 0.9999 221125_WJC_METTL3_EV_vs_WT_F01.18153.18153.2 6.69E-06 18-Nov K.LGMNLMNELK.Q "sp|Q16890|TPD53_HUMAN,tr|E9PNK6|E9PNK6_HUMAN,tr|E9PNQ9|E9PNQ9_HUMAN,tr|E9PPQ1|E9PPQ1_HUMAN,tr|J3KNE7|J3KNE7_HUMAN" 5 1161.5886 1.4 5851 18153 2 1161.587422 581.8016 Tumor protein D53 OS=Homo sapiens OX=9606 GN=TPD52L1 PE=1 SV=1 6 3518.9 - 1.74E+06 - - - -1.015 - 2.352 0.482 - 349.5 1 2 0 -0.0012 10 0 0 0 2.60E+07 1.85E+07 - - - 4.988 0.9983 221125_WJC_METTL3_EV_vs_WT_F01.18155.18155.2 0.00631 14-Sep R.EMVLEIIR.E "sp|Q96I24|FUBP3_HUMAN,sp|Q96AE4|FUBP1_HUMAN,tr|E9PEB5|E9PEB5_HUMAN" 3 1001.558 1.2 5853 18155 2 1001.556578 501.7863 Far upstream element-binding protein 3 OS=Homo sapiens OX=9606 GN=FUBP3 PE=1 SV=2 4.53 3519 - 794878 - - - -1.3729 - 1.77 0.196 - 227.8 1 2 0 -0.0014 8 0 0 0 1.62E+07 1.35E+07 - - - 2.2103 0.9997 221125_WJC_METTL3_EV_vs_WT_F01.18157.18157.2 0.000268 22-Sep K.GLTPSQIGVILR.D "sp|P62277|RS13_HUMAN,tr|J3KMX5|J3KMX5_HUMAN" 2 1252.7503 1.05 5855 18157 2 1252.749958 627.3824 40S ribosomal protein S13 OS=Homo sapiens OX=9606 GN=RPS13 PE=1 SV=2 9.75 3519.3 - 559831 - - - -0.2906 - 2.134 0.322 - 348.1 1 2 0 -0.0004 12 0 0 0 8.01E+07 7.66E+07 - - - 3.4136 0.9998 221125_WJC_METTL3_EV_vs_WT_F01.18163.18163.2 0.00264 16-Nov R.ELGELIPLR.Q "sp|Q14980|NUMA1_HUMAN,tr|A0A087WY61|A0A087WY61_HUMAN,tr|H0YFY6|H0YFY6_HUMAN,tr|K4DIE0|K4DIE0_HUMAN" 4 1038.6073 1.12 5860 18163 2 1038.606832 520.3109 Nuclear mitotic apparatus protein 1 OS=Homo sapiens OX=9606 GN=NUMA1 PE=1 SV=2 4.53 3520 - 1.55E+06 - - - -0.4949 - 2.04 0.376 - 574.5 1 2 0 -0.0005 9 0 0 0 3.13E+07 2.79E+07 - - - 3.8806 0.999 221125_WJC_METTL3_EV_vs_WT_F01.18165.18165.2 0.0957 18-Aug R.LGLLGLPAPK[136.11].N sp|Q99459|CDC5L_HUMAN 1 985.6416 1.35 5861 18165 2 985.640894 493.8281 Cell division cycle 5-like protein OS=Homo sapiens OX=9606 GN=CDC5L PE=1 SV=2 8.75 3520.2 - 1.02E+07 - - - -0.6686 - 1.755 0.241 - 160.9 1 2 0 -0.0007 10 0 0 0 3.89E+08 2.87E+08 - - - 2.3908 0.9877 221125_WJC_METTL3_EV_vs_WT_F01.18172.18172.2 0.295 18-Jul K.LGMNLMNELK[136.11].Q "sp|Q16890|TPD53_HUMAN,tr|E9PNK6|E9PNK6_HUMAN,tr|E9PNQ9|E9PNQ9_HUMAN,tr|E9PPQ1|E9PPQ1_HUMAN,tr|J3KNE7|J3KNE7_HUMAN" 5 1169.6028 1.39 5868 18172 2 1169.601515 585.8087 Tumor protein D53 OS=Homo sapiens OX=9606 GN=TPD52L1 PE=1 SV=1 6 3520.8 - 930441 - - - -1.0995 - 1.253 0.159 - 101.5 3 2 0 -0.0013 10 0 0 0 2.60E+07 1.87E+07 - - - 0.6314 0.8964 221125_WJC_METTL3_EV_vs_WT_F01.18176.18176.2 0.897 20-Sep F.IGAIAIGDLVK[136.11].S "sp|P78371|TCPB_HUMAN,tr|F8VQ14|F8VQ14_HUMAN,tr|F5GWF6|F5GWF6_HUMAN" 3 1076.6685 0.52 5870 18176 2 1076.669232 539.3415 T-complex protein 1 subunit beta OS=Homo sapiens OX=9606 GN=CCT2 PE=1 SV=4 5.84 3521.2 - 1.83E+06 - - - 0.6836 - 1.989 0.141 - 150.9 1 1 0 0.0007 11 0 0 0 7.97E+07 1.52E+08 - - - 1.9424 0.9977 221125_WJC_METTL3_EV_vs_WT_F01.18177.18177.2 0.0229 12-Jul R.VWSDFLR[166.11].V "sp|Q9BUK6|MSTO1_HUMAN,tr|A0A3B3IUD2|A0A3B3IUD2_HUMAN" 2 931.4791 1.41 5871 18177 2 931.480642 466.7468 Protein misato homolog 1 OS=Homo sapiens OX=9606 GN=MSTO1 PE=1 SV=1 5.81 3521.3 - 1.02E+06 - - - 1.6318 - 1.29 0.315 - 174.7 1 2 0 0.0015 7 0 0 0 6.29E+07 4.47E+07 - - - 2.174 0.9285 221125_WJC_METTL3_EV_vs_WT_F01.18178.18178.2 2.97 12-May R.NITLWLK[136.11].Y "sp|Q9BZJ0|CRNL1_HUMAN,tr|Q5JY65|Q5JY65_HUMAN" 2 894.5418 1.31 5872 18178 2 894.54129 448.2782 Crooked neck-like protein 1 OS=Homo sapiens OX=9606 GN=CRNKL1 PE=1 SV=4 8.75 3521.4 - 1.51E+06 - - - -0.6137 - 1.059 0.061 - 68.3 5 2 0 -0.0005 7 0 0 0 3.72E+07 2.85E+07 - - - -0.6392 0.9985 221125_WJC_METTL3_EV_vs_WT_F01.18183.18183.2 0.0075 12-Jul R.VWSDFLR.V "sp|Q9BUK6|MSTO1_HUMAN,tr|A0A3B3IUD2|A0A3B3IUD2_HUMAN" 2 921.4709 1.4 5875 18183 2 921.470486 461.7427 Protein misato homolog 1 OS=Homo sapiens OX=9606 GN=MSTO1 PE=1 SV=1 5.81 3522.1 - 1.60E+06 - - - -0.3972 - 1.32 0.288 - 247.4 1 2 0 -0.0004 7 0 0 0 6.25E+07 4.46E+07 - - - 2.0477 0.8551 221125_WJC_METTL3_EV_vs_WT_F01.18184.18184.2 0.215 20-Oct F.IGAIAIGDLVK.S "sp|P78371|TCPB_HUMAN,tr|F8VQ14|F8VQ14_HUMAN,tr|F5GWF6|F5GWF6_HUMAN" 3 1068.6543 0.52 5876 18184 2 1068.654046 535.3344 T-complex protein 1 subunit beta OS=Homo sapiens OX=9606 GN=CCT2 PE=1 SV=4 5.84 3522.1 - 1.73E+06 - - - -0.2339 - 2.15 0.074 - 163.2 2 1 0 -0.0003 11 0 0 0 7.97E+07 1.52E+08 - - - 1.5238 0.9998 221125_WJC_METTL3_EV_vs_WT_F01.18185.18185.2 0.00983 22-Dec R.LEALLEAAGIGK[136.11].L "sp|O75179|ANR17_HUMAN,sp|Q8IWZ3|ANKH1_HUMAN,tr|E9PDP5|E9PDP5_HUMAN,tr|H0YM23|H0YM23_HUMAN,tr|A0A1W2PQ15|A0A1W2PQ15_HUMAN" 5 1191.6954 2.27 5877 18185 2 1191.695532 596.855 Ankyrin repeat domain-containing protein 17 OS=Homo sapiens OX=9606 GN=ANKRD17 PE=1 SV=3 4.53 3522.2 - 4.47E+06 - - - 0.078 - 2.434 0.386 - 471 1 2 0 0.0001 12 0 0 0 2.38E+08 1.05E+08 - - - 4.2325 0.9672 221125_WJC_METTL3_EV_vs_WT_F01.18186.18186.2 0.277 14-Aug K.DLIPYLEK.L sp|O75643|U520_HUMAN 1 989.5433 2.43 5878 18186 2 989.539314 495.779 U5 small nuclear ribonucleoprotein 200 kDa helicase OS=Homo sapiens OX=9606 GN=SNRNP200 PE=1 SV=2 4.37 3522.2 - 2.76E+06 - - - -4.0766 - 1.27 0.219 - 147 1 2 0 -0.004 8 0 0 0 7.70E+07 3.17E+07 - - - 1.3781 0.9998 221125_WJC_METTL3_EV_vs_WT_F01.18197.18197.2 0.000146 22-Oct K.YILAATLDNTLK.L sp|P61964|WDR5_HUMAN 1 1334.7446 1.25 5885 18197 2 1334.74351 668.3796 WD repeat-containing protein 5 OS=Homo sapiens OX=9606 GN=WDR5 PE=1 SV=1 5.83 3523.6 - 2.14E+06 - - - -0.7927 - 1.843 0.531 - 246.4 1 2 0 -0.0011 12 0 0 0 4.04E+07 3.24E+07 - - - 4.5713 0.9998 221125_WJC_METTL3_EV_vs_WT_F01.18200.18200.2 3.01E-05 22-Nov K.GLTPSQIGVILR[166.11].D "sp|P62277|RS13_HUMAN,tr|J3KMX5|J3KMX5_HUMAN" 2 1262.7586 1.05 5886 18200 2 1262.758413 632.3866 40S ribosomal protein S13 OS=Homo sapiens OX=9606 GN=RPS13 PE=1 SV=2 9.75 3524 - 3.56E+06 - - - -0.1418 - 2.424 0.374 - 560.7 1 2 0 -0.0002 12 0 0 0 8.01E+07 7.66E+07 - - - 4.133 0.9998 221125_WJC_METTL3_EV_vs_WT_F01.18203.18203.2 4.32E-05 20-Sep R.FVVMVTPEDLK[136.11].A "sp|Q13085|ACACA_HUMAN,sp|O00763|ACACB_HUMAN,tr|S4R3S7|S4R3S7_HUMAN,tr|A0A087X0W4|A0A087X0W4_HUMAN" 4 1284.6879 0.91 5889 18203 2 1284.687443 643.3512 Acetyl-CoA carboxylase 1 OS=Homo sapiens OX=9606 GN=ACACA PE=1 SV=2 4.37 3524.3 - 267253 - - - -0.3643 - 1.802 0.481 - 192.2 1 2 0 -0.0005 11 0 0 0 3.93E+06 4.33E+06 - - - 4.1866 0.9888 221125_WJC_METTL3_EV_vs_WT_F01.18208.18208.2 0.0218 14-Jul K.YLELLGYR[166.11].K "sp|O94979|SC31A_HUMAN,tr|H0Y9K1|H0Y9K1_HUMAN,tr|H7BXG7|H7BXG7_HUMAN,tr|D6RHZ5|D6RHZ5_HUMAN,tr|D6REX3|D6REX3_HUMAN,tr|H0YAB3|H0YAB3_HUMAN,tr|H0Y8V7|H0Y8V7_HUMAN" 7 1035.5629 1.23 5892 18208 2 1035.562638 518.7887 Protein transport protein Sec31A OS=Homo sapiens OX=9606 GN=SEC31A PE=1 SV=3 6 3524.9 - 1.60E+06 - - - -0.2067 - 1.642 0 - 157.3 1 2 0 -0.0002 8 0 0 0 2.73E+07 2.22E+07 - - - 0.5366 0.778 221125_WJC_METTL3_EV_vs_WT_F01.18214.18214.2 0.0577 18-Jul K.GDITR[166.11]DR[166.11]HSK.T "sp|Q9H270|VPS11_HUMAN,tr|A0A087WXL6|A0A087WXL6_HUMAN,tr|B7Z879|B7Z879_HUMAN" 3 1203.6223 - 5896 18214 2 1203.621417 602.8184 Vacuolar protein sorting-associated protein 11 homolog OS=Homo sapiens OX=9606 GN=VPS11 PE=1 SV=1 8.75 3525.7 - 1.28E+06 - - - -0.7527 - 1.327 0.033 - 150.7 1 2 2 -0.0009 10 0 0 0 - - - - - 0.0742 0.9995 221125_WJC_METTL3_EV_vs_WT_F01.18215.18215.2 0.0014 16-Oct R.TTLLPGLLK[136.11].T sp|Q9NSD9|SYFB_HUMAN 1 962.6256 0.56 5897 18215 2 962.624727 482.3201 Phenylalanine--tRNA ligase beta subunit OS=Homo sapiens OX=9606 GN=FARSB PE=1 SV=3 8.41 3525.8 - 1.23E+06 - - - -0.8737 - 1.804 0.313 - 296.7 1 2 0 -0.0008 9 0 0 0 9.49E+06 1.70E+07 - - - 3.0595 0.9984 221125_WJC_METTL3_EV_vs_WT_F01.18216.18216.2 0.0485 12-Aug K.LYSLFLK.Y "sp|Q9P2R7|SUCB1_HUMAN,tr|Q5T9Q5|Q5T9Q5_HUMAN,tr|A0A0U1RRI1|A0A0U1RRI1_HUMAN,tr|A0A2R8YDQ9|A0A2R8YDQ9_HUMAN,tr|A0A2R8Y6Y7|A0A2R8Y6Y7_HUMAN,tr|Q5T9Q8|Q5T9Q8_HUMAN" 6 882.5215 1.17 5898 18216 2 882.521602 442.268 "Succinate--CoA ligase [ADP-forming] subunit beta, mitochondrial OS=Homo sapiens OX=9606 GN=SUCLA2 PE=1 SV=3" 8.59 3525.9 - 980494 - - - 0.1258 - 1.301 0.287 - 139.5 1 2 0 0.0001 7 0 0 0 1.36E+07 1.16E+07 - - - 1.9945 0.9916 221125_WJC_METTL3_EV_vs_WT_F01.18217.18217.2 0.808 12-Jul K.LYSLFLK[136.11].Y "sp|Q9P2R7|SUCB1_HUMAN,tr|Q5T9Q5|Q5T9Q5_HUMAN,tr|A0A0U1RRI1|A0A0U1RRI1_HUMAN,tr|A0A2R8YDQ9|A0A2R8YDQ9_HUMAN,tr|A0A2R8Y6Y7|A0A2R8Y6Y7_HUMAN,tr|Q5T9Q8|Q5T9Q8_HUMAN" 6 890.5357 1.14 5899 18217 2 890.535587 446.2751 "Succinate--CoA ligase [ADP-forming] subunit beta, mitochondrial OS=Homo sapiens OX=9606 GN=SUCLA2 PE=1 SV=3" 8.59 3526.1 - 900788 - - - -0.1168 - 1.04 0.212 - 116.4 1 2 0 -0.0001 7 0 0 0 1.46E+07 1.28E+07 - - - 0.7311 0.9965 221125_WJC_METTL3_EV_vs_WT_F01.18218.18218.2 0.297 16-Sep R.FLGTEVLLR[166.11].L "sp|Q8IXT5|RB12B_HUMAN,tr|B9ZVT1|B9ZVT1_HUMAN" 2 1056.6207 1.9 5900 18218 2 1056.61805 529.3176 RNA-binding protein 12B OS=Homo sapiens OX=9606 GN=RBM12B PE=1 SV=2 6 3526.2 - 891227 - - - -2.5089 - 1.811 0.203 - 216.3 1 2 0 -0.0027 9 0 0 0 2.76E+07 1.45E+07 - - - 2.2576 0.9846 221125_WJC_METTL3_EV_vs_WT_F01.18224.18224.2 0.0574 20-Jul K.NATMPVTMLIR.V sp|Q9UKX7|NUP50_HUMAN 1 1245.6573 2.37 5904 18224 2 1245.662336 623.836 Nuclear pore complex protein Nup50 OS=Homo sapiens OX=9606 GN=NUP50 PE=1 SV=2 9.75 3527 - 317022 - - - 4.0035 - 1.41 0.269 - 130.5 1 2 0 0.005 11 0 0 0 6.67E+06 2.81E+06 - - - 1.9558 0.9998 221125_WJC_METTL3_EV_vs_WT_F01.18228.18228.2 0.000163 24-Oct K.LFPDTPLALDANK.K sp|Q12906|ILF3_HUMAN 1 1413.7504 1.16 5908 18228 2 1413.749843 707.8825 Interleukin enhancer-binding factor 3 OS=Homo sapiens OX=9606 GN=ILF3 PE=1 SV=3 4.21 3527.4 - 408087 - - - -0.3805 - 1.73 0.498 - 295.6 1 2 0 -0.0005 13 0 0 0 1.33E+08 1.15E+08 - - - 4.1258 0.9115 221125_WJC_METTL3_EV_vs_WT_F01.18229.18229.2 1.84 14-Jun R.WVVPVLPK.G "sp|O00507|USP9Y_HUMAN,sp|Q93008|USP9X_HUMAN" 2 936.5797 1.27 5909 18229 2 936.57741 469.2971 Probable ubiquitin carboxyl-terminal hydrolase FAF-Y OS=Homo sapiens OX=9606 GN=USP9Y PE=2 SV=2 8.75 3527.6 - 381485 - - - -2.4173 - 1.208 0.061 - 80.8 3 2 0 -0.0023 8 0 0 0 4.48E+06 3.53E+06 - - - -0.1524 0.9997 221125_WJC_METTL3_EV_vs_WT_F01.18231.18231.2 0.000275 24-Oct K.LFPDTPLALDANK[136.11].K sp|Q12906|ILF3_HUMAN 1 1421.7646 0.73 5911 18231 2 1421.76672 711.8896 Interleukin enhancer-binding factor 3 OS=Homo sapiens OX=9606 GN=ILF3 PE=1 SV=3 4.21 3527.8 - 363101 - - - 1.5045 - 2.069 0.443 - 294.8 1 2 0 0.0021 13 0 0 0 3.07E+06 4.19E+06 - - - 4.1784 0.9998 221125_WJC_METTL3_EV_vs_WT_F01.18237.18237.2 0.00273 16-Sep K.LLQDFFNGR[166.11].D "sp|P0DMV8|HS71A_HUMAN,sp|P0DMV9|HS71B_HUMAN,tr|V9GZ37|V9GZ37_HUMAN,tr|A0A0G2JIW1|A0A0G2JIW1_HUMAN" 4 1118.5748 0.16 5916 18237 2 1118.575929 560.2947 Heat shock 70 kDa protein 1A OS=Homo sapiens OX=9606 GN=HSPA1A PE=1 SV=1 5.84 3528.6 - 1.76E+07 - - - 0.9977 - 1.998 0.482 - 333.1 1 2 0 0.0011 9 0 0 0 5.71E+08 3.62E+09 - - - 4.6031 0.9905 221125_WJC_METTL3_EV_vs_WT_F01.18238.18238.2 1.92 18-Sep R.YLYTLVITDK[136.11].E "sp|P63173|RL38_HUMAN,tr|J3KT73|J3KT73_HUMAN,tr|J3QL01|J3QL01_HUMAN" 3 1235.6893 1.38 5917 18238 2 1235.690672 618.8519 60S ribosomal protein L38 OS=Homo sapiens OX=9606 GN=RPL38 PE=1 SV=2 5.83 3528.7 - 670996 - - - 1.1176 - 1.272 0.159 - 205.6 1 2 0 0.0014 10 0 0 0 1.99E+07 1.44E+07 - - - 0.8865 0.9978 221125_WJC_METTL3_EV_vs_WT_F01.18239.18239.2 0.0225 14-Jul R.ILFFNTPK[136.11].K "sp|P48556|PSMD8_HUMAN,tr|K7EJR3|K7EJR3_HUMAN,tr|R4GMR5|R4GMR5_HUMAN,tr|K7EJC1|K7EJC1_HUMAN" 4 986.5681 0.56 5918 18239 2 986.569122 494.2913 26S proteasome non-ATPase regulatory subunit 8 OS=Homo sapiens OX=9606 GN=PSMD8 PE=1 SV=2 8.75 3528.7 - 4.55E+06 - - - 1.0825 - 1.495 0.233 - 122.3 1 2 0 0.0011 8 0 0 0 4.13E+07 7.42E+07 - - - 1.9744 0.9814 221125_WJC_METTL3_EV_vs_WT_F01.18240.18240.2 0.000432 16-Oct R.FLGTEVLLR.L "sp|Q8IXT5|RB12B_HUMAN,tr|B9ZVT1|B9ZVT1_HUMAN" 2 1046.6124 2.24 5919 18240 2 1046.619327 524.3135 RNA-binding protein 12B OS=Homo sapiens OX=9606 GN=RBM12B PE=1 SV=2 6 3528.8 - 1.87E+06 - - - 6.5889 - 1.571 0.419 - 240.9 1 2 0 0.0069 9 0 0 0 3.32E+07 1.48E+07 - - - 3.4404 0.9644 221125_WJC_METTL3_EV_vs_WT_F01.18242.18242.2 0.515 12-Jul K.DLLLPIK[136.11].T "sp|Q5VT66|MARC1_HUMAN,tr|H7BYZ9|H7BYZ9_HUMAN,tr|A0A494C1P3|A0A494C1P3_HUMAN" 3 818.5357 1.16 5921 18242 2 818.536176 410.2751 Mitochondrial amidoxime-reducing component 1 OS=Homo sapiens OX=9606 GN=MTARC1 PE=1 SV=1 5.84 3529 - 1.27E+06 - - - 0.5925 - 1.29 0.001 - 198.9 1 2 0 0.0005 7 0 0 0 1.56E+07 1.35E+07 - - - -0.1449 0.9996 221125_WJC_METTL3_EV_vs_WT_F01.18243.18243.2 0.00481 14-Jul R.VDEIIWVK[136.11].T sp|Q86U44|MTA70_HUMAN 1 1008.5735 0.3 5922 18243 2 1008.574619 505.294 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 4.37 3529.1 - 1.15E+06 - - - 1.0768 - 1.859 0.368 - 136 1 2 0 0.0011 8 0 0 0 1.10E+07 3.65E+07 - - - 3.6287 0.9997 221125_WJC_METTL3_EV_vs_WT_F01.18246.18246.2 2.53E-05 18-Nov R.YLNWIGVPTK.V "sp|Q16875|F263_HUMAN,sp|O60825|F262_HUMAN,tr|A0A1W2PR17|A0A1W2PR17_HUMAN,tr|Q5W015|Q5W015_HUMAN,tr|A0A1W2PNV9|A0A1W2PNV9_HUMAN,tr|F2Z2I2|F2Z2I2_HUMAN,tr|F6RAZ1|F6RAZ1_HUMAN,tr|F6XNB3|F6XNB3_HUMAN,tr|Q5VX20|Q5VX20_HUMAN" 9 1189.6495 1.1 5925 18246 2 1189.648273 595.832 "6-phosphofructo-2-kinase\fructose-2,6-bisphosphatase 3 OS=Homo sapiens OX=9606 GN=PFKFB3 PE=1 SV=1" 8.59 3529.4 - 812268 - - - -1.0692 - 1.768 0.43 - 394.4 1 2 0 -0.0013 10 0 0 0 3.88E+07 3.52E+07 - - - 3.8072 0.998 221125_WJC_METTL3_EV_vs_WT_F01.18247.18247.2 0.15 22-Oct K.ALAVGGLGSIIR.V sp|Q9BPX5|ARP5L_HUMAN 1 1125.687 1.08 5926 18247 2 1125.689839 563.8508 Actin-related protein 2\3 complex subunit 5-like protein OS=Homo sapiens OX=9606 GN=ARPC5L PE=1 SV=1 9.79 3529.5 - 643005 - - - 2.5282 - 2.133 0.243 - 354.1 1 2 0 0.0028 12 0 0 0 4.88E+06 4.51E+06 - - - 2.8281 0.9717 221125_WJC_METTL3_EV_vs_WT_F01.18249.18249.2 0.0835 12-Jul R.NAFDLFK[136.11].L "sp|Q99549|MPP8_HUMAN,tr|A0A0A0MT47|A0A0A0MT47_HUMAN" 2 861.4476 0.73 5928 18249 2 861.449072 431.7311 M-phase phosphoprotein 8 OS=Homo sapiens OX=9606 GN=MPHOSPH8 PE=1 SV=2 5.84 3529.7 - 497858 - - - 1.7041 - 1.37 0.043 - 192.7 1 2 0 0.0015 7 0 0 0 2.65E+06 3.63E+06 - - - 0.3556 0.9997 221125_WJC_METTL3_EV_vs_WT_F01.18254.18254.2 0.00317 16-Oct R.YLDVSILGK[136.11].F sp|Q86U44|MTA70_HUMAN 1 1014.5841 0.29 5932 18254 2 1014.585951 508.2993 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 5.83 3530.3 - 2.44E+06 - - - 1.8264 - 1.963 0.478 - 246.6 1 2 0 0.0019 9 0 0 0 2.90E+07 9.88E+07 - - - 4.5222 0.9983 221125_WJC_METTL3_EV_vs_WT_F01.18255.18255.2 0.0102 14-Jul R.EALAFIIR[166.11].S "sp|O00541|PESC_HUMAN,tr|B3KXD6|B3KXD6_HUMAN,tr|B5MCF9|B5MCF9_HUMAN" 3 941.5574 0.59 5933 18255 2 941.558923 471.786 Pescadillo homolog OS=Homo sapiens OX=9606 GN=PES1 PE=1 SV=1 6.1 3530.3 - 2.11E+06 - - - 1.6473 - 1.568 0.277 - 157.2 1 2 0 0.0016 8 0 0 0 7.61E+06 1.30E+07 - - - 2.443 0.9718 221125_WJC_METTL3_EV_vs_WT_F01.18256.18256.2 1.1 12-Jul K.DLLLPIK.T "sp|Q5VT66|MARC1_HUMAN,tr|H7BYZ9|H7BYZ9_HUMAN,tr|A0A494C1P3|A0A494C1P3_HUMAN" 3 810.5215 1.16 5934 18256 2 810.522193 406.268 Mitochondrial amidoxime-reducing component 1 OS=Homo sapiens OX=9606 GN=MTARC1 PE=1 SV=1 5.84 3530.4 - 2.06E+06 - - - 0.8661 - 1.376 0.003 - 203.5 1 2 0 0.0007 7 0 0 0 1.56E+07 1.35E+07 - - - 0.0743 0.9944 221125_WJC_METTL3_EV_vs_WT_F01.18257.18257.2 0.575 12-Jun K.LIFYDLR[166.11].G "sp|Q15046|SYK_HUMAN,sp|Q5VW00|DC122_HUMAN,sp|Q5T6F0|DCA12_HUMAN,tr|H3BVA8|H3BVA8_HUMAN" 4 948.5308 0.73 5935 18257 2 948.532274 475.2727 Lysine--tRNA ligase OS=Homo sapiens OX=9606 GN=KARS1 PE=1 SV=3 5.84 3530.4 - 1.79E+06 - - - 1.5297 - 1.335 0.199 - 148 1 2 0 0.0015 7 0 0 0 3.02E+07 4.13E+07 - - - 1.4259 0.9984 221125_WJC_METTL3_EV_vs_WT_F01.18258.18258.2 0.000294 14-Sep K.MDELQLFR.G "sp|P55072|TERA_HUMAN,tr|A0A7P0Z4C6|A0A7P0Z4C6_HUMAN,tr|A0A7I2V2Y2|A0A7I2V2Y2_HUMAN,tr|A0A7P0T8Q5|A0A7P0T8Q5_HUMAN,tr|C9JUP7|C9JUP7_HUMAN,tr|A0A7P0T971|A0A7P0T971_HUMAN,tr|A0A7P0TAW3|A0A7P0TAW3_HUMAN,tr|A0A7P0Z4D1|A0A7P0Z4D1_HUMAN,tr|A0A7I2V540|A0A7I2V540_HUMAN,tr|A0A7P0T8A3|A0A7P0T8A3_HUMAN,tr|A0A7P0TAQ1|A0A7P0TAQ1_HUMAN,tr|A0A7I2V5G8|A0A7I2V5G8_HUMAN,tr|A0A7P0T946|A0A7P0T946_HUMAN,tr|A0A7P0TBK7|A0A7P0TBK7_HUMAN" 14 1050.5168 1.25 5936 18258 2 1050.519902 526.2657 Transitional endoplasmic reticulum ATPase OS=Homo sapiens OX=9606 GN=VCP PE=1 SV=4 4.37 3530.5 - 1.72E+06 - - - 2.9376 - 2.143 0.275 - 488.3 1 2 0 0.0031 8 0 0 0 1.88E+07 1.50E+07 - - - 3.37 0.9888 221125_WJC_METTL3_EV_vs_WT_F01.18259.18259.2 0.185 16-Oct R.TTLLPGLLK.T sp|Q9NSD9|SYFB_HUMAN 1 954.6114 0.56 5937 18259 2 954.611876 478.313 Phenylalanine--tRNA ligase beta subunit OS=Homo sapiens OX=9606 GN=FARSB PE=1 SV=3 8.41 3530.6 - 1.08E+06 - - - 0.5322 - 1.589 0.031 - 261.2 1 2 0 0.0005 9 0 0 0 9.49E+06 1.70E+07 - - - 0.6096 0.9988 221125_WJC_METTL3_EV_vs_WT_F01.18261.18261.2 0.000255 18-Oct R.YLNWIGVPTK[136.11].V "sp|Q16875|F263_HUMAN,sp|O60825|F262_HUMAN,tr|A0A1W2PR17|A0A1W2PR17_HUMAN,tr|Q5W015|Q5W015_HUMAN,tr|A0A1W2PNV9|A0A1W2PNV9_HUMAN,tr|F2Z2I2|F2Z2I2_HUMAN,tr|F6RAZ1|F6RAZ1_HUMAN,tr|F6XNB3|F6XNB3_HUMAN,tr|Q5VX20|Q5VX20_HUMAN" 9 1197.6637 1.15 5939 18261 2 1197.665444 599.8391 "6-phosphofructo-2-kinase\fructose-2,6-bisphosphatase 3 OS=Homo sapiens OX=9606 GN=PFKFB3 PE=1 SV=1" 8.59 3530.8 - 852472 - - - 1.4186 - 1.515 0.333 - 330.7 1 2 0 0.0017 10 0 0 0 3.88E+07 3.38E+07 - - - 2.6596 0.8929 221125_WJC_METTL3_EV_vs_WT_F01.18263.18263.3 0.0163 Aug-32 R.LLLYHLHPF.L sp|O60512|B4GT3_HUMAN 1 1151.6492 - 5941 18263 3 1151.651372 384.8903 "Beta-1,4-galactosyltransferase 3 OS=Homo sapiens OX=9606 GN=B4GALT3 PE=1 SV=2" 6.92 3531 - 472971 - - - 1.9285 - 1.48 0.354 - 60.9 1 1 0 0.0022 9 0 0 0 - - - - - 3.6677 0.864 221125_WJC_METTL3_EV_vs_WT_F01.18265.18265.2 2.54 12-Jun R.NLPFLIK.K sp|Q86TB9|PATL1_HUMAN 1 843.5218 0.89 5943 18265 2 843.522882 422.7682 Protein PAT1 homolog 1 OS=Homo sapiens OX=9606 GN=PATL1 PE=1 SV=2 8.75 3531.3 - 350632 - - - 1.2531 - 0.966 0.057 - 82.6 3 2 0 0.0011 7 0 0 0 6.53E+06 7.31E+06 - - - -0.8611 1 221125_WJC_METTL3_EV_vs_WT_F01.18266.18266.2 1.45E-06 18/28 R.LPAAGVGDMVMATVK.K "sp|P62829|RL23_HUMAN,tr|J3KT29|J3KT29_HUMAN,tr|B9ZVP7|B9ZVP7_HUMAN,tr|C9JD32|C9JD32_HUMAN" 4 1458.7575 0.94 5944 18266 2 1458.756044 730.386 60S ribosomal protein L23 OS=Homo sapiens OX=9606 GN=RPL23 PE=1 SV=1 5.84 3531.4 - 286099 - - - -0.9686 - 3.291 0.585 - 867.4 1 2 0 -0.0014 15 0 0 0 5.96E+08 6.35E+08 - - - 6.29 1 221125_WJC_METTL3_EV_vs_WT_F01.18267.18267.2 1.79E-09 18/28 R.LPAAGVGDMVMATVK[136.11].K "sp|P62829|RL23_HUMAN,tr|J3KT29|J3KT29_HUMAN,tr|B9ZVP7|B9ZVP7_HUMAN,tr|C9JD32|C9JD32_HUMAN" 4 1466.7717 0.94 5945 18267 2 1466.770568 734.3931 60S ribosomal protein L23 OS=Homo sapiens OX=9606 GN=RPL23 PE=1 SV=1 5.84 3531.6 - 284185 - - - -0.7424 - 3.521 0.597 - 1312.2 1 2 0 -0.0011 15 0 0 0 5.96E+08 6.35E+08 - - - 6.5448 0.9997 221125_WJC_METTL3_EV_vs_WT_F01.18272.18272.3 5.56E-06 Dec-72 R.IQEIIEQLDVTTSEYEKEK.L "sp|P10809|CH60_HUMAN,tr|A0A7I2V2X6|A0A7I2V2X6_HUMAN,tr|A0A7I2YQK6|A0A7I2YQK6_HUMAN,tr|A0A7I2V599|A0A7I2V599_HUMAN" 4 2294.1529 2.84 5950 18272 3 2294.156247 765.7249 "60 kDa heat shock protein, mitochondrial OS=Homo sapiens OX=9606 GN=HSPD1 PE=1 SV=2" 4.14 3532.2 - 220674 - - - 1.4419 - 2.543 0.468 - 128.9 1 2 1 0.0033 19 0 0 0 1.24E+06 4.35E+05 - - - 6.0499 0.9965 221125_WJC_METTL3_EV_vs_WT_F01.18277.18277.2 0.615 12-Jun K.LIFYDLR.G "sp|Q15046|SYK_HUMAN,sp|Q5VW00|DC122_HUMAN,sp|Q5T6F0|DCA12_HUMAN,tr|H3BVA8|H3BVA8_HUMAN" 4 938.5226 0.73 5954 18277 2 938.523268 470.2686 Lysine--tRNA ligase OS=Homo sapiens OX=9606 GN=KARS1 PE=1 SV=3 5.84 3532.7 - 3.19E+06 - - - 0.7618 - 1.403 0.206 - 116.3 2 2 0 0.0007 7 0 0 0 3.02E+07 4.14E+07 - - - 1.5007 0.9832 221125_WJC_METTL3_EV_vs_WT_F01.18280.18280.2 0.787 12-Jul K.LYNLFLK[136.11].L "sp|Q96I99|SUCB2_HUMAN,tr|E9PDQ8|E9PDQ8_HUMAN" 2 917.5466 4.45 5957 18280 2 917.547579 459.7806 "Succinate--CoA ligase [GDP-forming] subunit beta, mitochondrial OS=Homo sapiens OX=9606 GN=SUCLG2 PE=1 SV=2" 8.59 3533 - 1.37E+06 - - - 1.0779 - 1.418 0.045 - 160.8 1 2 0 0.001 7 0 0 0 6.01E+07 1.35E+07 - - - 0.4797 0.8713 221125_WJC_METTL3_EV_vs_WT_F01.18281.18281.2 0.0577 12-Apr K.DFDFESA.N "sp|Q8ND56|LS14A_HUMAN,tr|A0A140TA76|A0A140TA76_HUMAN,tr|K7EMZ9|K7EMZ9_HUMAN" 3 829.313 - 5958 18281 2 829.313638 415.6638 Protein LSM14 homolog A OS=Homo sapiens OX=9606 GN=LSM14A PE=1 SV=3 3.49 3533.1 - 924328 - - - 0.7524 - 1.019 0.361 - 99.5 1 1 0 0.0006 7 0 0 0 - - - - - 1.7668 0.9633 221125_WJC_METTL3_EV_vs_WT_F01.18282.18282.2 2.56 14-Aug K.C[160.03]QLLFALK[136.11].V "sp|Q9BRJ7|TIRR_HUMAN,tr|K7EIN2|K7EIN2_HUMAN" 2 999.5667 1.33 5959 18282 2 999.568489 500.7906 Tudor-interacting repair regulator protein OS=Homo sapiens OX=9606 GN=NUDT16L1 PE=1 SV=1 8.22 3533.2 - 848316 - - - 1.8158 - 1.266 0.064 - 182.5 1 2 0 0.0018 8 0 0 0 8.54E+06 6.45E+06 - - - 0.2245 0.9857 221125_WJC_METTL3_EV_vs_WT_F01.18283.18283.2 5.65 14-Aug R.ILFFNTPK.K "sp|P48556|PSMD8_HUMAN,tr|K7EJR3|K7EJR3_HUMAN,tr|R4GMR5|R4GMR5_HUMAN,tr|K7EJC1|K7EJC1_HUMAN" 4 978.5539 0.55 5960 18283 2 978.554868 490.2842 26S proteasome non-ATPase regulatory subunit 8 OS=Homo sapiens OX=9606 GN=PSMD8 PE=1 SV=2 8.75 3533.3 - 809315 - - - 1.0362 - 1.284 0.106 - 120.7 1 2 0 0.001 8 0 0 0 4.15E+07 7.48E+07 - - - 0.5775 0.9843 221125_WJC_METTL3_EV_vs_WT_F01.18284.18284.2 0.879 12-Jul R.NLPFLIK[136.11].K sp|Q86TB9|PATL1_HUMAN 1 851.536 1.12 5961 18284 2 851.537207 426.7753 Protein PAT1 homolog 1 OS=Homo sapiens OX=9606 GN=PATL1 PE=1 SV=2 8.75 3533.4 - 777967 - - - 1.3881 - 1.307 0.101 - 164.9 1 2 0 0.0012 7 0 0 0 8.48E+06 7.59E+06 - - - 0.6349 0.9993 221125_WJC_METTL3_EV_vs_WT_F01.18285.18285.2 0.211 16-Nov K.SLLAWQSLR[166.11].R "sp|Q15149|PLEC_HUMAN,tr|H0YDN1|H0YDN1_HUMAN" 2 1082.6112 1.45 5962 18285 2 1082.612268 542.3129 Plectin OS=Homo sapiens OX=9606 GN=PLEC PE=1 SV=3 9.47 3533.5 - 607033 - - - 0.9874 - 2.06 0.255 - 491.2 1 2 0 0.0011 9 0 0 0 4.11E+06 2.84E+06 - - - 3.0149 0.9904 221125_WJC_METTL3_EV_vs_WT_F01.18287.18287.2 2.4 12-Jun R.VLVEWLR[166.11].D "sp|P49354|FNTA_HUMAN,tr|E9PQP6|E9PQP6_HUMAN,tr|E9PPM9|E9PPM9_HUMAN,tr|H0YCW1|H0YCW1_HUMAN,tr|B3KVN2|B3KVN2_HUMAN" 5 923.5468 0.84 5964 18287 2 923.545908 462.7807 Protein farnesyltransferase\geranylgeranyltransferase type-1 subunit alpha OS=Homo sapiens OX=9606 GN=FNTA PE=1 SV=1 5.97 3533.8 - 303130 - - - -0.9745 - 1.3 0.121 - 104.7 1 2 0 -0.0009 7 0 0 0 1.84E+06 2.21E+06 - - - 0.7657 0.9998 221125_WJC_METTL3_EV_vs_WT_F01.18296.18296.2 0.0523 20-Nov K.LVFLGLDNAGK[136.11].T "sp|Q9NR31|SAR1A_HUMAN,sp|Q9Y6B6|SAR1B_HUMAN,tr|D6RAA2|D6RAA2_HUMAN,tr|D6RD69|D6RD69_HUMAN,tr|X1WI22|X1WI22_HUMAN,tr|Q5SQT8|Q5SQT8_HUMAN,tr|D6RDB2|D6RDB2_HUMAN" 7 1153.6587 1.1 5971 18296 2 1153.659562 577.8366 GTP-binding protein SAR1a OS=Homo sapiens OX=9606 GN=SAR1A PE=1 SV=1 5.84 3534.9 - 8.97E+06 - - - 0.7827 - 2.218 0.431 - 379.2 1 2 0 0.0009 11 0 0 0 2.38E+09 2.17E+09 - - - 4.3791 0.9998 221125_WJC_METTL3_EV_vs_WT_F01.18297.18297.2 0.00461 20-Nov K.LVFLGLDNAGK.T "sp|Q9NR31|SAR1A_HUMAN,sp|Q9Y6B6|SAR1B_HUMAN,tr|D6RAA2|D6RAA2_HUMAN,tr|D6RD69|D6RD69_HUMAN,tr|X1WI22|X1WI22_HUMAN,tr|Q5SQT8|Q5SQT8_HUMAN,tr|D6RDB2|D6RDB2_HUMAN" 7 1145.6445 1.1 5972 18297 2 1145.646001 573.8295 GTP-binding protein SAR1a OS=Homo sapiens OX=9606 GN=SAR1A PE=1 SV=1 5.84 3534.9 - 7.70E+06 - - - 1.346 - 2.202 0.491 - 413.6 1 2 0 0.0015 11 0 0 0 2.38E+09 2.17E+09 - - - 4.8025 0.9917 221125_WJC_METTL3_EV_vs_WT_F01.18299.18299.2 0.165 14-Jun R.FLIQNVLR[166.11].L "sp|P41252|SYIC_HUMAN,tr|A0A804HL54|A0A804HL54_HUMAN,tr|A0A804HKU1|A0A804HKU1_HUMAN,tr|A0A804HK69|A0A804HK69_HUMAN,tr|A0A804HIV9|A0A804HIV9_HUMAN,tr|A0A804HJN6|A0A804HJN6_HUMAN,tr|A0A804HHW9|A0A804HHW9_HUMAN,tr|A0A0A0MSX9|A0A0A0MSX9_HUMAN,tr|J3KR24|J3KR24_HUMAN,tr|A0A804HJ36|A0A804HJ36_HUMAN" 10 1011.6105 0.78 5974 18299 2 1011.611773 506.8125 "Isoleucine--tRNA ligase, cytoplasmic OS=Homo sapiens OX=9606 GN=IARS1 PE=1 SV=2" 9.75 3535 - 4.27E+06 - - - 1.2871 - 1.45 0.119 - 125.8 1 2 0 0.0013 8 0 0 0 4.98E+07 6.36E+07 - - - 1.0401 0.9999 221125_WJC_METTL3_EV_vs_WT_F01.18302.18302.3 3.86E-06 Dec-56 R.LPAAGVGDMVMATVK.K "sp|P62829|RL23_HUMAN,tr|J3KT29|J3KT29_HUMAN,tr|B9ZVP7|B9ZVP7_HUMAN,tr|C9JD32|C9JD32_HUMAN" 4 1458.7575 0.94 5977 18302 3 1458.760161 487.2598 60S ribosomal protein L23 OS=Homo sapiens OX=9606 GN=RPL23 PE=1 SV=1 5.84 3535.2 - 1.46E+06 - - - 1.8536 - 2.386 0.414 - 99.7 1 2 0 0.0027 15 0 0 0 1.93E+08 2.06E+08 - - - 5.4241 0.948 221125_WJC_METTL3_EV_vs_WT_F01.18303.18303.2 0.00757 20-Sep K.FENAFLSHVVS.Q sp|P25705|ATPA_HUMAN 1 1248.6139 - 5978 18303 2 1248.615732 625.3142 "ATP synthase subunit alpha, mitochondrial OS=Homo sapiens OX=9606 GN=ATP5F1A PE=1 SV=1" 5.24 3535.3 - 1.32E+06 - - - 1.4768 - 1.544 0.37 - 120.6 1 1 0 0.0018 11 0 0 0 - - - - - 2.9483 0.9998 221125_WJC_METTL3_EV_vs_WT_F01.18304.18304.2 7.97E-06 16-Oct R.MADFWLTEK.D sp|Q9NRX2|RM17_HUMAN 1 1139.5321 1.54 5979 18304 2 1139.534256 570.7733 "39S ribosomal protein L17, mitochondrial OS=Homo sapiens OX=9606 GN=MRPL17 PE=1 SV=1" 4.37 3535.3 - 1.24E+06 - - - 1.8639 - 2.017 0.531 - 367 1 2 0 0.0021 9 0 0 0 7.63E+06 4.95E+06 - - - 4.9921 0.9949 221125_WJC_METTL3_EV_vs_WT_F01.18306.18306.2 0.0856 12-Jun R.FPFEIVK[136.11].M "sp|Q9UQ16|DYN3_HUMAN,sp|Q05193|DYN1_HUMAN,sp|P50570|DYN2_HUMAN,tr|A0A0D9SFB1|A0A0D9SFB1_HUMAN,tr|A0A1B0GU67|A0A1B0GU67_HUMAN,tr|A0A0D9SFE4|A0A0D9SFE4_HUMAN,tr|H7C5U0|H7C5U0_HUMAN,tr|E5RIK2|E5RIK2_HUMAN,tr|K7EMQ3|K7EMQ3_HUMAN,tr|A0A0U1RQP1|A0A0U1RQP1_HUMAN,tr|E5RHK8|E5RHK8_HUMAN" 11 886.5044 0.71 5981 18306 2 886.503333 444.2595 Dynamin-3 OS=Homo sapiens OX=9606 GN=DNM3 PE=1 SV=4 6 3535.5 - 762861 - - - -1.1935 - 1.21 0.221 - 109.8 1 2 0 -0.0011 7 0 0 0 1.06E+07 1.49E+07 - - - 1.277 0.9997 221125_WJC_METTL3_EV_vs_WT_F01.18308.18308.2 0.000101 20-Dec K.YAALYQPLFDK.R "sp|Q99733|NP1L4_HUMAN,tr|A8MXH2|A8MXH2_HUMAN,tr|C9J6D1|C9J6D1_HUMAN,tr|E9PJJ2|E9PJJ2_HUMAN,tr|E9PNW0|E9PNW0_HUMAN,tr|E9PKT8|E9PKT8_HUMAN,tr|E9PS34|E9PS34_HUMAN,tr|C9JZI7|C9JZI7_HUMAN,tr|E9PNJ7|E9PNJ7_HUMAN" 9 1327.6812 0.96 5983 18308 2 1327.683916 664.8479 Nucleosome assembly protein 1-like 4 OS=Homo sapiens OX=9606 GN=NAP1L4 PE=1 SV=1 5.83 3535.7 - 494586 - - - 2.0163 - 2.227 0.452 - 479.2 1 2 0 0.0027 11 0 0 0 5.15E+06 5.37E+06 - - - 4.5446 0.9995 221125_WJC_METTL3_EV_vs_WT_F01.18309.18309.2 0.000636 20-Nov R.FYSLLDPSYAK.N sp|P46977|STT3A_HUMAN 1 1302.6496 3.13 5984 18309 2 1302.652818 652.3321 Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit STT3A OS=Homo sapiens OX=9606 GN=STT3A PE=1 SV=2 5.83 3535.9 - 488809 - - - 2.4673 - 1.86 0.489 - 380.5 1 2 0 0.0032 11 0 0 0 8.41E+06 2.69E+06 - - - 4.3306 0.9657 221125_WJC_METTL3_EV_vs_WT_F01.18311.18311.2 1.12 16-Jun R.GFTIPEAFR.G sp|O00299|CLIC1_HUMAN 1 1036.5342 1.94 5986 18311 2 1036.53504 519.2744 Chloride intracellular channel protein 1 OS=Homo sapiens OX=9606 GN=CLIC1 PE=1 SV=4 6 3536.1 - 478953 - - - 0.8287 - 1.139 0.099 - 62.5 3 2 0 0.0009 9 0 0 0 2.32E+06 1.20E+06 - - - -0.0647 0.9998 221125_WJC_METTL3_EV_vs_WT_F01.18315.18315.2 0.000863 22-Oct R.VPLSTVLLDPTR[166.11].S sp|Q9Y2I1|NISCH_HUMAN 1 1319.7688 0.55 5990 18315 2 1319.76984 660.8917 Nischarin OS=Homo sapiens OX=9606 GN=NISCH PE=1 SV=3 5.81 3536.6 - 182567 - - - 0.7713 - 2.039 0.426 - 263 1 2 0 0.001 12 0 0 0 8.35E+05 1.52E+06 - - - 4.0617 0.9993 221125_WJC_METTL3_EV_vs_WT_F01.18317.18317.2 1.83E-05 20-Sep R.ALMDSLGPEWR.L sp|Q15785|TOM34_HUMAN 1 1273.6125 1.19 5991 18317 2 1273.61623 637.8135 Mitochondrial import receptor subunit TOM34 OS=Homo sapiens OX=9606 GN=TOMM34 PE=1 SV=2 4.37 3536.9 - 459447 - - - 2.9232 - 1.998 0.477 - 386.2 1 2 0 0.0037 11 0 0 0 1.05E+07 8.84E+06 - - - 4.4354 1 221125_WJC_METTL3_EV_vs_WT_F01.18319.18319.3 9.49E-08 13/56 R.LPAAGVGDMVMATVK[136.11].K "sp|P62829|RL23_HUMAN,tr|J3KT29|J3KT29_HUMAN,tr|B9ZVP7|B9ZVP7_HUMAN,tr|C9JD32|C9JD32_HUMAN" 4 1466.7717 0.94 5993 18319 3 1466.772976 489.9312 60S ribosomal protein L23 OS=Homo sapiens OX=9606 GN=RPL23 PE=1 SV=1 5.84 3537.1 - 3.01E+06 - - - 0.8993 - 2.727 0.537 - 222.5 1 2 0 0.0013 15 0 0 0 1.93E+08 2.06E+08 - - - 7.1444 0.9983 221125_WJC_METTL3_EV_vs_WT_F01.18320.18320.2 0.275 16-Sep R.GDLLFLTNR.V "sp|P67812|SC11A_HUMAN,tr|H0YNA5|H0YNA5_HUMAN,tr|H0YNG3|H0YNG3_HUMAN,tr|H0YNX5|H0YNX5_HUMAN" 4 1047.5713 1.51 5994 18320 2 1047.572442 524.7929 Signal peptidase complex catalytic subunit SEC11A OS=Homo sapiens OX=9606 GN=SEC11A PE=1 SV=1 5.84 3537.2 - 1.51E+06 - - - 1.0949 - 1.969 0.163 - 283.4 1 2 0 0.0011 9 0 0 0 1.60E+07 1.06E+07 - - - 2.2047 0.999 221125_WJC_METTL3_EV_vs_WT_F01.18324.18324.2 0.00269 18-Sep K.ELLTSFGPLK[136.11].A "sp|P26368|U2AF2_HUMAN,tr|K7ENG2|K7ENG2_HUMAN" 2 1111.6369 0.87 5998 18324 2 1111.6344 556.8257 Splicing factor U2AF 65 kDa subunit OS=Homo sapiens OX=9606 GN=U2AF2 PE=1 SV=4 6.1 3537.5 - 806766 - - - -2.2139 - 1.708 0.365 - 235.7 1 2 0 -0.0025 10 0 0 0 1.19E+08 1.36E+08 - - - 3.2304 0.998 221125_WJC_METTL3_EV_vs_WT_F01.18325.18325.2 0.161 12-Jul R.FPFEIVK.M "sp|Q9UQ16|DYN3_HUMAN,sp|Q05193|DYN1_HUMAN,sp|P50570|DYN2_HUMAN,tr|A0A0D9SFB1|A0A0D9SFB1_HUMAN,tr|A0A1B0GU67|A0A1B0GU67_HUMAN,tr|A0A0D9SFE4|A0A0D9SFE4_HUMAN,tr|H7C5U0|H7C5U0_HUMAN,tr|E5RIK2|E5RIK2_HUMAN,tr|K7EMQ3|K7EMQ3_HUMAN,tr|A0A0U1RQP1|A0A0U1RQP1_HUMAN,tr|E5RHK8|E5RHK8_HUMAN" 11 878.4902 0.7 5999 18325 2 878.488971 440.2524 Dynamin-3 OS=Homo sapiens OX=9606 GN=DNM3 PE=1 SV=4 6 3537.6 - 607678 - - - -1.3887 - 1.57 0.218 - 158.3 1 2 0 -0.0012 7 0 0 0 1.03E+07 1.46E+07 - - - 2.08 0.9992 221125_WJC_METTL3_EV_vs_WT_F01.18329.18329.2 0.0021 20-Jul R.ALMDSLGPEWR[166.11].L sp|Q15785|TOM34_HUMAN 1 1283.6208 1.19 6003 18329 2 1283.623118 642.8177 Mitochondrial import receptor subunit TOM34 OS=Homo sapiens OX=9606 GN=TOMM34 PE=1 SV=2 4.37 3538.1 - 279901 - - - 1.8237 - 1.658 0.387 - 221.6 1 2 0 0.0023 11 0 0 0 1.05E+07 8.84E+06 - - - 3.2664 0.9999 221125_WJC_METTL3_EV_vs_WT_F01.18334.18334.2 0.000176 22-Nov K.GGIVGMTLPIAR.D "sp|Q99714|HCD2_HUMAN,tr|A0A804HHW5|A0A804HHW5_HUMAN" 2 1183.6747 0.66 6007 18334 2 1183.674466 592.8446 3-hydroxyacyl-CoA dehydrogenase type-2 OS=Homo sapiens OX=9606 GN=HSD17B10 PE=1 SV=3 9.75 3538.6 - 1.78E+06 - - - -0.2095 - 2.136 0.5 - 369.7 1 2 0 -0.0002 12 0 0 0 2.38E+07 3.59E+07 - - - 4.7308 0.9998 221125_WJC_METTL3_EV_vs_WT_F01.18335.18335.2 0.000161 20-Nov R.LYEAYLPETFR.R "sp|Q8WU79|SMAP2_HUMAN,tr|A0A087WV97|A0A087WV97_HUMAN,tr|X6RCC3|X6RCC3_HUMAN" 3 1400.6976 1.63 6008 18335 2 1400.69882 701.3561 Stromal membrane-associated protein 2 OS=Homo sapiens OX=9606 GN=SMAP2 PE=1 SV=1 4.53 3538.7 - 1.49E+06 - - - 0.8589 - 2.315 0.466 - 474.5 1 2 0 0.0012 11 0 0 0 1.98E+08 1.22E+08 - - - 4.7533 0.9853 221125_WJC_METTL3_EV_vs_WT_F01.18338.18338.2 5.65E-05 16-Sep K.LFTTMELMR.W sp|O00232|PSD12_HUMAN 1 1140.5671 0.92 6011 18338 2 1140.575702 571.2908 26S proteasome non-ATPase regulatory subunit 12 OS=Homo sapiens OX=9606 GN=PSMD12 PE=1 SV=3 6 3539 - 648609 - - - 7.5094 - 1.82 0.481 - 270.5 1 2 0 0.0086 9 0 0 0 1.68E+07 1.83E+07 - - - 4.3234 0.9974 221125_WJC_METTL3_EV_vs_WT_F01.18339.18339.2 0.00215 20-Oct K.YAALYQPLFDK[136.11].R "sp|Q99733|NP1L4_HUMAN,tr|A8MXH2|A8MXH2_HUMAN,tr|C9J6D1|C9J6D1_HUMAN,tr|E9PJJ2|E9PJJ2_HUMAN,tr|E9PNW0|E9PNW0_HUMAN,tr|E9PKT8|E9PKT8_HUMAN,tr|E9PS34|E9PS34_HUMAN,tr|C9JZI7|C9JZI7_HUMAN,tr|E9PNJ7|E9PNJ7_HUMAN" 9 1335.6954 0.96 6012 18339 2 1335.689722 668.855 Nucleosome assembly protein 1-like 4 OS=Homo sapiens OX=9606 GN=NAP1L4 PE=1 SV=1 5.83 3539.1 - 638308 - - - -4.2802 - 1.917 0.418 - 294.7 1 2 0 -0.0057 11 0 0 0 5.15E+06 5.37E+06 - - - 3.887 0.9996 221125_WJC_METTL3_EV_vs_WT_F01.18344.18344.2 0.00185 18-Sep K.ELLTSFGPLK.A "sp|P26368|U2AF2_HUMAN,tr|K7ENG2|K7ENG2_HUMAN" 2 1103.6227 0.87 6015 18344 2 1103.623321 552.8186 Splicing factor U2AF 65 kDa subunit OS=Homo sapiens OX=9606 GN=U2AF2 PE=1 SV=4 6.1 3539.8 - 3.53E+06 - - - 0.598 - 1.849 0.369 - 257.3 1 2 0 0.0007 10 0 0 0 1.19E+08 1.36E+08 - - - 3.4819 0.9999 221125_WJC_METTL3_EV_vs_WT_F01.18347.18347.2 0.000194 13/20 K.LGLENAEALIR[166.11].L sp|P10155|RO60_HUMAN 1 1207.68 1.54 6018 18347 2 1207.679451 604.8473 60 kDa SS-A\Ro ribonucleoprotein OS=Homo sapiens OX=9606 GN=RO60 PE=1 SV=2 4.53 3540 - 1.75E+06 - - - -0.4604 - 2.811 0.367 - 525 1 2 0 -0.0006 11 0 0 0 2.88E+07 1.87E+07 - - - 4.5475 0.9922 221125_WJC_METTL3_EV_vs_WT_F01.18348.18348.2 0.00282 16-Aug R.SPTWFGIPR[166.11].L "sp|P78347|GTF2I_HUMAN,tr|A0A494C1K3|A0A494C1K3_HUMAN" 2 1069.5584 1.3 6019 18348 2 1069.562857 535.7865 General transcription factor II-I OS=Homo sapiens OX=9606 GN=GTF2I PE=1 SV=2 9.47 3540.1 - 3.06E+06 - - - 4.1344 - 1.66 0.289 - 319.1 1 2 0 0.0044 9 0 0 0 4.63E+08 3.56E+08 - - - 2.6404 0.9997 221125_WJC_METTL3_EV_vs_WT_F01.18350.18350.2 0.00101 20-Oct K.NPLIINSIIDK[136.11].A "sp|Q9UNQ2|DIM1_HUMAN,tr|A0A494C0G7|A0A494C0G7_HUMAN,tr|B4DRY2|B4DRY2_HUMAN,tr|A0A7P0T8X7|A0A7P0T8X7_HUMAN,tr|A0A0C4DGB1|A0A0C4DGB1_HUMAN,tr|A0A7P0T967|A0A7P0T967_HUMAN,tr|A0A7P0T9J1|A0A7P0T9J1_HUMAN,tr|A0A7P0Z4I0|A0A7P0Z4I0_HUMAN,tr|A0A7P0T9Y7|A0A7P0T9Y7_HUMAN,tr|D6RCL3|D6RCL3_HUMAN" 10 1246.7376 0.93 6021 18350 2 1246.736478 624.3761 Probable dimethyladenosine transferase OS=Homo sapiens OX=9606 GN=DIMT1 PE=1 SV=1 5.84 3540.3 - 1.00E+06 - - - -0.9304 - 2.181 0.375 - 489.4 1 2 0 -0.0012 11 0 0 0 7.51E+06 8.12E+06 - - - 3.9199 0.9429 221125_WJC_METTL3_EV_vs_WT_F01.18352.18352.2 0.0195 12-Aug L.SGFLVWR[166.11].R "sp|Q9NP84|TNR12_HUMAN,sp|Q96T88|UHRF1_HUMAN,tr|I3L1J9|I3L1J9_HUMAN,tr|A0A087WWG9|A0A087WWG9_HUMAN,tr|A0A087WTW0|A0A087WTW0_HUMAN,tr|A0A087WVR3|A0A087WVR3_HUMAN" 6 873.4736 1.1 6023 18352 2 873.472361 437.7441 Tumor necrosis factor receptor superfamily member 12A OS=Homo sapiens OX=9606 GN=TNFRSF12A PE=1 SV=1 9.47 3540.6 - 696073 - - - -1.4677 - 1.658 0.285 - 234.2 1 1 0 -0.0013 7 0 0 0 1.64E+07 1.49E+07 - - - 2.7477 0.9933 221125_WJC_METTL3_EV_vs_WT_F01.18353.18353.2 0.143 14-Aug R.FLVALISR[166.11].R "sp|Q9Y2H2|SAC2_HUMAN,tr|A0A3B3ISI3|A0A3B3ISI3_HUMAN,tr|A0A3B3IRJ9|A0A3B3IRJ9_HUMAN,tr|A0A3B3ITL0|A0A3B3ITL0_HUMAN,tr|A0A3B3ITR9|A0A3B3ITR9_HUMAN,tr|A0A3B3ISJ5|A0A3B3ISJ5_HUMAN" 6 927.5781 0.83 6024 18353 2 927.581403 464.7963 Phosphatidylinositide phosphatase SAC2 OS=Homo sapiens OX=9606 GN=INPP5F PE=1 SV=3 9.75 3540.7 - 638649 - - - 3.5523 - 1.767 0.22 - 192.4 1 2 0 0.0033 8 0 0 0 6.03E+06 7.23E+06 - - - 2.3818 0.9999 221125_WJC_METTL3_EV_vs_WT_F01.18355.18355.2 1.61E-06 14/22 R.LLYMAIDGVAPR.A sp|Q9H0D6|XRN2_HUMAN 1 1317.7115 1.07 6026 18355 2 1317.712248 659.863 5'-3' exoribonuclease 2 OS=Homo sapiens OX=9606 GN=XRN2 PE=1 SV=1 5.84 3541 - 533269 - - - 0.573 - 2.597 0.524 - 919.1 1 2 0 0.0008 12 0 0 0 7.14E+07 6.65E+07 - - - 5.4221 1 221125_WJC_METTL3_EV_vs_WT_F01.18356.18356.2 2.00E-05 15/22 R.LLYMAIDGVAPR[166.11].A sp|Q9H0D6|XRN2_HUMAN 1 1327.7198 1.08 6027 18356 2 1327.721766 664.8672 5'-3' exoribonuclease 2 OS=Homo sapiens OX=9606 GN=XRN2 PE=1 SV=1 5.84 3541.1 - 479549 - - - 1.5086 - 2.731 0.555 - 983.1 1 2 0 0.002 12 0 0 0 7.12E+07 6.60E+07 - - - 5.7831 0.9998 221125_WJC_METTL3_EV_vs_WT_F01.18361.18361.2 5.64E-05 22-Nov K.FGEAIGMGFPVK[136.11].V "sp|P78347|GTF2I_HUMAN,tr|A0A494C1K3|A0A494C1K3_HUMAN" 2 1259.6464 1.45 6030 18361 2 1259.644503 630.8305 General transcription factor II-I OS=Homo sapiens OX=9606 GN=GTF2I PE=1 SV=2 6 3541.8 - 6.12E+06 - - - -1.4901 - 2.08 0.527 - 322.6 1 2 0 -0.0019 12 0 0 0 3.35E+08 2.31E+08 - - - 4.8598 0.9999 221125_WJC_METTL3_EV_vs_WT_F01.18362.18362.2 3.18E-05 16-Sep R.SPTWFGIPR[166.11].L "sp|P78347|GTF2I_HUMAN,tr|A0A494C1K3|A0A494C1K3_HUMAN" 2 1069.5584 1.3 6031 18362 2 1069.557896 535.7865 General transcription factor II-I OS=Homo sapiens OX=9606 GN=GTF2I PE=1 SV=2 9.47 3541.8 - 5.08E+06 - - - -0.5039 - 1.933 0.53 - 469.4 1 2 0 -0.0005 9 0 0 0 4.63E+08 3.56E+08 - - - 4.8621 0.9997 221125_WJC_METTL3_EV_vs_WT_F01.18363.18363.2 0.00105 16-Sep R.SPTWFGIPR.L "sp|P78347|GTF2I_HUMAN,tr|A0A494C1K3|A0A494C1K3_HUMAN" 2 1059.5502 1.3 6032 18363 2 1059.550103 530.7824 General transcription factor II-I OS=Homo sapiens OX=9606 GN=GTF2I PE=1 SV=2 9.47 3541.9 - 4.97E+06 - - - -0.0585 - 1.903 0.371 - 460.5 1 2 0 -0.0001 9 0 0 0 4.63E+08 3.56E+08 - - - 3.6427 0.9576 221125_WJC_METTL3_EV_vs_WT_F01.18365.18365.2 0.000491 18-Sep V.PFVDAFQLER.A sp|Q14152|EIF3A_HUMAN 1 1220.619 1.23 6034 18365 2 1220.61614 611.3168 Eukaryotic translation initiation factor 3 subunit A OS=Homo sapiens OX=9606 GN=EIF3A PE=1 SV=1 4.37 3542 - 1.17E+06 - - - -2.321 - 1.778 0.413 - 271.2 1 1 0 -0.0028 10 0 0 0 1.02E+07 8.26E+06 - - - 3.6969 0.8807 221125_WJC_METTL3_EV_vs_WT_F01.18366.18366.2 0.0955 12-Jun L.SGFLVWR.R "sp|Q9NP84|TNR12_HUMAN,sp|Q96T88|UHRF1_HUMAN,tr|I3L1J9|I3L1J9_HUMAN,tr|A0A087WWG9|A0A087WWG9_HUMAN,tr|A0A087WTW0|A0A087WTW0_HUMAN,tr|A0A087WVR3|A0A087WVR3_HUMAN" 6 863.4654 1.1 6035 18366 2 863.463644 432.74 Tumor necrosis factor receptor superfamily member 12A OS=Homo sapiens OX=9606 GN=TNFRSF12A PE=1 SV=1 9.47 3542.1 - 1.16E+06 - - - -2.0024 - 1.528 0.264 - 147 1 1 0 -0.0017 7 0 0 0 1.62E+07 1.47E+07 - - - 2.3337 0.9964 221125_WJC_METTL3_EV_vs_WT_F01.18370.18370.3 0.0917 Sep-40 K.LVFLGLDNAGK.T "sp|Q9NR31|SAR1A_HUMAN,sp|Q9Y6B6|SAR1B_HUMAN,tr|D6RAA2|D6RAA2_HUMAN,tr|D6RD69|D6RD69_HUMAN,tr|X1WI22|X1WI22_HUMAN,tr|Q5SQT8|Q5SQT8_HUMAN,tr|D6RDB2|D6RDB2_HUMAN" 7 1145.6445 1.22 6039 18370 3 1145.642318 382.8888 GTP-binding protein SAR1a OS=Homo sapiens OX=9606 GN=SAR1A PE=1 SV=1 5.84 3542.6 - 595146 - - - -1.8688 - 1.584 0.262 - 83.7 1 2 0 -0.0021 11 0 0 0 4.04E+06 3.30E+06 - - - 2.7671 0.9999 221125_WJC_METTL3_EV_vs_WT_F01.18376.18376.2 0.00031 13/22 R.IGFDVVTLSGTR[166.11].G "sp|Q9BSD7|NTPCR_HUMAN,tr|Q5TDF0|Q5TDF0_HUMAN" 2 1273.6906 1.11 6043 18376 2 1273.688858 637.8526 Cancer-related nucleoside-triphosphatase OS=Homo sapiens OX=9606 GN=NTPCR PE=1 SV=1 5.84 3543.4 - 3.00E+06 - - - -1.3457 - 2.58 0.488 - 719.6 1 2 0 -0.0017 12 0 0 0 2.72E+08 2.45E+08 - - - 5.1386 0.9995 221125_WJC_METTL3_EV_vs_WT_F01.18379.18379.2 0.0241 18-Aug K.VLLLIDDEYK.V sp|Q8N766|EMC1_HUMAN 1 1219.67 0.23 6046 18379 2 1219.672252 610.8423 ER membrane protein complex subunit 1 OS=Homo sapiens OX=9606 GN=EMC1 PE=1 SV=1 4.03 3543.5 - 1.39E+06 - - - 1.8415 - 1.771 0.427 - 211.7 1 2 0 0.0022 10 0 0 0 1.02E+07 4.46E+07 - - - 3.7895 0.9995 221125_WJC_METTL3_EV_vs_WT_F01.18380.18380.3 0.0147 Oct-40 R.LYEAYLPETFR[166.11].R "sp|Q8WU79|SMAP2_HUMAN,tr|A0A087WV97|A0A087WV97_HUMAN,tr|X6RCC3|X6RCC3_HUMAN" 3 1410.7059 1.67 6047 18380 3 1410.705197 471.2426 Stromal membrane-associated protein 2 OS=Homo sapiens OX=9606 GN=SMAP2 PE=1 SV=1 4.53 3543.6 - 887151 - - - -0.4891 - 1.682 0.34 - 80 1 2 0 -0.0007 11 0 0 0 1.84E+07 1.10E+07 - - - 3.8077 0.9968 221125_WJC_METTL3_EV_vs_WT_F01.18381.18381.2 0.547 14-Sep R.FLVALISR.R "sp|Q9Y2H2|SAC2_HUMAN,tr|A0A3B3ISI3|A0A3B3ISI3_HUMAN,tr|A0A3B3IRJ9|A0A3B3IRJ9_HUMAN,tr|A0A3B3ITL0|A0A3B3ITL0_HUMAN,tr|A0A3B3ITR9|A0A3B3ITR9_HUMAN,tr|A0A3B3ISJ5|A0A3B3ISJ5_HUMAN" 6 917.5698 0.82 6048 18381 2 917.572485 459.7922 Phosphatidylinositide phosphatase SAC2 OS=Homo sapiens OX=9606 GN=INPP5F PE=1 SV=3 9.75 3543.8 - 817757 - - - 2.8848 - 1.836 0.238 - 271.9 1 2 0 0.0026 8 0 0 0 5.90E+06 7.23E+06 - - - 2.6305 0.95 221125_WJC_METTL3_EV_vs_WT_F01.18382.18382.2 0.000611 18-Sep K.AFHPFIAGPY.N "sp|Q00341|VIGLN_HUMAN,tr|A0A024R4E5|A0A024R4E5_HUMAN,tr|H7C0A4|H7C0A4_HUMAN,tr|H0Y394|H0Y394_HUMAN" 4 1118.5549 - 6049 18382 2 1118.552507 560.2847 Vigilin OS=Homo sapiens OX=9606 GN=HDLBP PE=1 SV=2 6.78 3543.9 - 699306 - - - -2.1537 - 1.455 0.443 - 173.9 1 1 0 -0.0024 10 0 0 0 - - - - - 3.359 0.9995 221125_WJC_METTL3_EV_vs_WT_F01.18385.18385.2 0.00556 14-Sep R.LMDNFLIR[166.11].E "sp|Q9NS91|RAD18_HUMAN,tr|F8WE49|F8WE49_HUMAN" 2 1030.5509 19.3 6052 18385 2 1030.549592 516.2827 E3 ubiquitin-protein ligase RAD18 OS=Homo sapiens OX=9606 GN=RAD18 PE=1 SV=2 5.84 3544.3 - 621213 - - - -1.276 - 1.755 0.341 - 221 1 2 0 -0.0013 8 0 0 0 1.40E+08 7.24E+06 - - - 3.2556 0.9999 221125_WJC_METTL3_EV_vs_WT_F01.18387.18387.2 1.49E-05 18-Nov R.YYAFDEAFVR[166.11].E "sp|O43427|FIBP_HUMAN,tr|E9PSD3|E9PSD3_HUMAN,tr|E9PJW6|E9PJW6_HUMAN" 3 1289.5956 0.69 6054 18387 2 1289.593924 645.8051 Acidic fibroblast growth factor intracellular-binding protein OS=Homo sapiens OX=9606 GN=FIBP PE=1 SV=3 4.37 3544.5 - 430051 - - - -1.3066 - 2.14 0.591 - 351.3 1 2 0 -0.0017 10 0 0 0 2.36E+06 3.43E+06 - - - 5.5292 0.9998 221125_WJC_METTL3_EV_vs_WT_F01.18390.18390.2 0.0012 22-Nov R.IGFDVVTLSGTR.G "sp|Q9BSD7|NTPCR_HUMAN,tr|Q5TDF0|Q5TDF0_HUMAN" 2 1263.6823 1.11 6055 18390 2 1263.682291 632.8484 Cancer-related nucleoside-triphosphatase OS=Homo sapiens OX=9606 GN=NTPCR PE=1 SV=1 5.84 3544.9 - 8.35E+06 - - - -0.0087 - 2.304 0.372 - 322 1 2 0 0 12 0 0 0 2.72E+08 2.45E+08 - - - 3.9847 0.9993 221125_WJC_METTL3_EV_vs_WT_F01.18391.18391.2 0.000751 18-Oct R.EDIVVPVYLR[166.11].E "sp|P51784|UBP11_HUMAN,tr|G5E9A6|G5E9A6_HUMAN" 2 1211.6789 0.55 6056 18391 2 1211.676294 606.8467 Ubiquitin carboxyl-terminal hydrolase 11 OS=Homo sapiens OX=9606 GN=USP11 PE=1 SV=3 4.37 3545 - 2.21E+06 - - - -2.187 - 1.898 0.377 - 372.3 1 2 0 -0.0027 10 0 0 0 1.41E+07 2.57E+07 - - - 3.6134 0.8552 221125_WJC_METTL3_EV_vs_WT_F01.18392.18392.2 0.0517 20-Jul K.VNAVYLLPVPK[136.11].Q "sp|P42694|HELZ_HUMAN,tr|J3QS41|J3QS41_HUMAN,tr|A0A075B6R3|A0A075B6R3_HUMAN" 3 1219.742 1.28 6057 18392 2 1220.743211 610.8783 Probable helicase with zinc finger domain OS=Homo sapiens OX=9606 GN=HELZ PE=1 SV=2 8.56 3545.1 - 1.59E+06 - - - 820.8424 - 1.396 0.28 - 136.3 1 2 0 1.0012 11 0 0 0 2.73E+08 2.14E+08 - - - 1.6972 0.9759 221125_WJC_METTL3_EV_vs_WT_F01.18393.18393.2 0.000968 12-Jul R.WFEAFVK.R "sp|Q99543|DNJC2_HUMAN,tr|F2Z3H0|F2Z3H0_HUMAN,tr|H7C3L7|H7C3L7_HUMAN,tr|F2Z3N9|F2Z3N9_HUMAN" 4 925.4698 0.62 6058 18393 2 925.467989 463.7422 DnaJ homolog subfamily C member 2 OS=Homo sapiens OX=9606 GN=DNAJC2 PE=1 SV=4 6 3545.2 - 1.57E+06 - - - -1.946 - 1.345 0.072 - 203.8 1 2 0 -0.0018 7 0 0 0 1.28E+07 2.06E+07 - - - 0.5114 0.9958 221125_WJC_METTL3_EV_vs_WT_F01.18394.18394.2 0.245 12-Jul R.VLFLIPK[136.11].N "sp|Q9P289|STK26_HUMAN,sp|O00506|STK25_HUMAN,sp|Q9Y6E0|STK24_HUMAN,tr|C9JDH9|C9JDH9_HUMAN,tr|C9J232|C9J232_HUMAN,tr|B4E0Y9|B4E0Y9_HUMAN,tr|B4DR80|B4DR80_HUMAN,tr|Q5JV98|Q5JV98_HUMAN,tr|Q8NBY1|Q8NBY1_HUMAN,tr|H7C279|H7C279_HUMAN,tr|C9JCC0|C9JCC0_HUMAN,tr|H0Y630|H0Y630_HUMAN,tr|C9J6L2|C9J6L2_HUMAN" 13 836.5615 0.98 6059 18394 2 836.560386 419.288 Serine\threonine-protein kinase 26 OS=Homo sapiens OX=9606 GN=STK26 PE=1 SV=2 8.72 3545.3 - 1.38E+06 - - - -1.346 - 1.326 0.209 - 206.5 1 2 0 -0.0011 7 0 0 0 2.07E+07 2.12E+07 - - - 1.4784 0.7936 221125_WJC_METTL3_EV_vs_WT_F01.18395.18395.2 0.0835 18-Sep R.LLVPDIQEIR.V "sp|Q12756|KIF1A_HUMAN,tr|A0A3B3ITW6|A0A3B3ITW6_HUMAN,tr|A0A3B3ITF7|A0A3B3ITF7_HUMAN,tr|A0A3B3ITE5|A0A3B3ITE5_HUMAN,tr|H7C3Y8|H7C3Y8_HUMAN,tr|A0A3B3IUA1|A0A3B3IUA1_HUMAN,tr|A0A3B3IT28|A0A3B3IT28_HUMAN,tr|A0A3F2YNW9|A0A3F2YNW9_HUMAN,tr|A0A3B3IU40|A0A3B3IU40_HUMAN,tr|A0A3B3ITK3|A0A3B3ITK3_HUMAN" 10 1194.6972 1.13 6060 18395 2 1194.689777 598.3559 Kinesin-like protein KIF1A OS=Homo sapiens OX=9606 GN=KIF1A PE=1 SV=2 4.37 3545.4 - 997649 - - - -6.2325 - 1.561 0.099 - 251.9 1 2 0 -0.0074 10 0 0 0 1.09E+07 9.60E+06 - - - 1.0129 0.9997 221125_WJC_METTL3_EV_vs_WT_F01.18396.18396.2 0.00298 16-Oct K.ALIEILATR.T "sp|P08133|ANXA6_HUMAN,tr|E5RK69|E5RK69_HUMAN,tr|E7EMC6|E7EMC6_HUMAN" 3 998.6124 1.19 6061 18396 2 998.613038 500.3135 Annexin A6 OS=Homo sapiens OX=9606 GN=ANXA6 PE=1 SV=3 6.05 3545.6 - 719273 - - - 0.6078 - 2.2 0.325 - 280.9 1 2 0 0.0006 9 0 0 0 5.71E+06 4.81E+06 - - - 3.7223 0.9999 221125_WJC_METTL3_EV_vs_WT_F01.18397.18397.2 5.78E-06 22-Dec R.VIQEGLEGLVLK[136.11].D sp|P49916|DNLI3_HUMAN 1 1304.7795 1.28 6062 18397 2 1304.780895 653.397 DNA ligase 3 OS=Homo sapiens OX=9606 GN=LIG3 PE=1 SV=2 4.53 3545.7 - 644166 - - - 1.0668 - 2.343 0.56 - 418.1 1 2 0 0.0014 12 0 0 0 1.06E+07 8.32E+06 - - - 5.417 0.8224 221125_WJC_METTL3_EV_vs_WT_F01.18400.18400.2 0.207 12-Jul S.LYITLIR[166.11].E "sp|P55160|NCKPL_HUMAN,sp|Q9BTE3|MCMBP_HUMAN,tr|F8W050|F8W050_HUMAN" 3 900.5672 0.19 6065 18400 2 900.566807 451.2909 Nck-associated protein 1-like OS=Homo sapiens OX=9606 GN=NCKAP1L PE=1 SV=3 8.75 3546.1 - 375905 - - - -0.4464 - 1.256 0.216 - 124.1 1 1 0 -0.0004 7 0 0 0 7.97E+05 4.26E+06 - - - 1.3585 0.9998 221125_WJC_METTL3_EV_vs_WT_F01.18404.18404.2 0.132 16-Oct R.YLTVAAVFR.G "sp|P04350|TBB4A_HUMAN,sp|P07437|TBB5_HUMAN,sp|P68371|TBB4B_HUMAN,tr|Q5ST81|Q5ST81_HUMAN,tr|Q5JP53|Q5JP53_HUMAN" 5 1038.5862 0.67 6067 18404 2 1038.585994 520.3004 Tubulin beta-4A chain OS=Homo sapiens OX=9606 GN=TUBB4A PE=1 SV=2 8.75 3546.6 - 1.09E+07 - - - -0.2138 - 2.066 0.389 - 364.1 1 2 0 -0.0002 9 0 0 0 5.21E+08 7.77E+08 - - - 4.0133 0.9998 221125_WJC_METTL3_EV_vs_WT_F01.18405.18405.2 0.00252 16-Oct R.LVLDWDSVR.A "sp|Q68EM7|RHG17_HUMAN,tr|C9IZD3|C9IZD3_HUMAN,tr|I3L4P6|I3L4P6_HUMAN" 3 1101.5819 1.45 6068 18405 2 1101.581217 551.7982 Rho GTPase-activating protein 17 OS=Homo sapiens OX=9606 GN=ARHGAP17 PE=1 SV=1 4.21 3546.7 - 8.66E+06 - - - -0.5828 - 1.959 0.476 - 359.8 1 2 0 -0.0006 9 0 0 0 8.14E+07 5.60E+07 - - - 4.5019 0.9978 221125_WJC_METTL3_EV_vs_WT_F01.18407.18407.2 0.175 12-Jul K.WMGIAFR.L "sp|Q9BUJ2|HNRL1_HUMAN,tr|M0QYZ0|M0QYZ0_HUMAN,tr|A0A0A0MRA5|A0A0A0MRA5_HUMAN,tr|M0R3F1|M0R3F1_HUMAN,tr|B7Z4B8|B7Z4B8_HUMAN" 5 879.4425 1.21 6070 18407 2 879.441631 440.7285 Heterogeneous nuclear ribonucleoprotein U-like protein 1 OS=Homo sapiens OX=9606 GN=HNRNPUL1 PE=1 SV=2 9.75 3546.7 - 3.60E+06 - - - -1.0211 - 1.295 0.271 - 228.3 1 2 0 -0.0009 7 0 0 0 4.12E+07 3.42E+07 - - - 1.8614 0.9998 221125_WJC_METTL3_EV_vs_WT_F01.18410.18410.2 5.54E-06 22-Nov R.VIQEGLEGLVLK.D sp|P49916|DNLI3_HUMAN 1 1296.7653 1.3 6073 18410 2 1296.763502 649.3899 DNA ligase 3 OS=Homo sapiens OX=9606 GN=LIG3 PE=1 SV=2 4.53 3547.1 - 1.17E+06 - - - -1.3888 - 2.362 0.521 - 352.3 1 2 0 -0.0018 12 0 0 0 1.08E+07 8.32E+06 - - - 5.1501 0.9996 221125_WJC_METTL3_EV_vs_WT_F01.18417.18417.2 0.000207 16-Oct R.FEALNLSFK[136.11].N "sp|P14859|PO2F1_HUMAN,sp|P09086|PO2F2_HUMAN,sp|Q9UKI9|PO2F3_HUMAN,tr|U3KQ96|U3KQ96_HUMAN,tr|U3KQN1|U3KQN1_HUMAN,tr|H0YKT2|H0YKT2_HUMAN,tr|H0YNW1|H0YNW1_HUMAN,tr|B5ME60|B5ME60_HUMAN,tr|H0YLC5|H0YLC5_HUMAN,tr|A0A0C4DG88|A0A0C4DG88_HUMAN,tr|A0A0A0MT46|A0A0A0MT46_HUMAN,tr|H0YLL6|H0YLL6_HUMAN" 12 1075.5793 1.46 6078 18417 2 1075.576947 538.7969 "POU domain, class 2, transcription factor 1 OS=Homo sapiens OX=9606 GN=POU2F1 PE=1 SV=2" 6 3548 - 4.41E+06 - - - -2.2314 - 1.869 0.473 - 248.1 1 2 0 -0.0024 9 0 0 0 2.34E+08 1.60E+08 - - - 4.3432 0.9979 221125_WJC_METTL3_EV_vs_WT_F01.18418.18418.2 0.0866 12-Jul K.WMGIAFR[166.11].L "sp|Q9BUJ2|HNRL1_HUMAN,tr|M0QYZ0|M0QYZ0_HUMAN,tr|A0A0A0MRA5|A0A0A0MRA5_HUMAN,tr|M0R3F1|M0R3F1_HUMAN,tr|B7Z4B8|B7Z4B8_HUMAN" 5 889.4508 1.21 6079 18418 2 889.450204 445.7327 Heterogeneous nuclear ribonucleoprotein U-like protein 1 OS=Homo sapiens OX=9606 GN=HNRNPUL1 PE=1 SV=2 9.75 3548 - 3.57E+06 - - - -0.669 - 1.145 0.314 - 269.7 1 2 0 -0.0006 7 0 0 0 4.12E+07 3.42E+07 - - - 1.7891 0.9998 221125_WJC_METTL3_EV_vs_WT_F01.18422.18422.2 0.000108 18-Nov R.APELFSYIAK.N "sp|Q8IZH2|XRN1_HUMAN,tr|H7C5E4|H7C5E4_HUMAN" 2 1137.607 3.19 6083 18422 2 1137.607644 569.8108 5'-3' exoribonuclease 1 OS=Homo sapiens OX=9606 GN=XRN1 PE=1 SV=1 6.05 3548.5 - 777927 - - - 0.5564 - 2.103 0.47 - 387.6 1 2 0 0.0006 10 0 0 0 3.33E+07 1.05E+07 - - - 4.5872 0.9991 221125_WJC_METTL3_EV_vs_WT_F01.18428.18428.2 1.77 12-Aug R.VLFLIPK.N "sp|Q9P289|STK26_HUMAN,sp|O00506|STK25_HUMAN,sp|Q9Y6E0|STK24_HUMAN,tr|C9JDH9|C9JDH9_HUMAN,tr|C9J232|C9J232_HUMAN,tr|B4E0Y9|B4E0Y9_HUMAN,tr|B4DR80|B4DR80_HUMAN,tr|Q5JV98|Q5JV98_HUMAN,tr|Q8NBY1|Q8NBY1_HUMAN,tr|H7C279|H7C279_HUMAN,tr|C9JCC0|C9JCC0_HUMAN,tr|H0Y630|H0Y630_HUMAN,tr|C9J6L2|C9J6L2_HUMAN" 13 828.5473 0.98 6087 18428 2 828.546553 415.2809 Serine\threonine-protein kinase 26 OS=Homo sapiens OX=9606 GN=STK26 PE=1 SV=2 8.72 3549.2 - 1.74E+06 - - - -0.9161 - 1.589 0.287 - 261.1 1 2 0 -0.0008 7 0 0 0 2.07E+07 2.12E+07 - - - 2.6279 0.9994 221125_WJC_METTL3_EV_vs_WT_F01.18431.18431.2 0.0033 22-Oct R.LGMIVAEVVSAR.L sp|Q9Y4R8|TELO2_HUMAN 1 1243.6958 4.22 6090 18431 2 1243.694626 622.8552 Telomere length regulation protein TEL2 homolog OS=Homo sapiens OX=9606 GN=TELO2 PE=1 SV=2 6 3549.5 - 737797 - - - -0.9785 - 1.532 0.397 - 162.1 1 2 0 -0.0012 12 0 0 0 1.41E+07 3.35E+06 - - - 3.0952 0.7896 221125_WJC_METTL3_EV_vs_WT_F01.18432.18432.2 1.66 18-Aug R.FPPVVFYTPK[136.11].E "sp|Q6P2Q9|PRP8_HUMAN,tr|I3L3Z8|I3L3Z8_HUMAN" 2 1201.6627 0.59 6091 18432 2 1201.667669 601.8386 Pre-mRNA-processing-splicing factor 8 OS=Homo sapiens OX=9606 GN=PRPF8 PE=1 SV=2 8.59 3549.6 - 674564 - - - 4.1501 - 1.211 0.062 - 148.1 1 2 0 0.005 10 0 0 0 8.35E+06 1.41E+07 - - - 0.0318 0.9999 221125_WJC_METTL3_EV_vs_WT_F01.18434.18434.2 4.94E-07 13/24 K.ILTPLVSLDTPGK[136.11].A "sp|Q9HC38|GLOD4_HUMAN,tr|I3L1I0|I3L1I0_HUMAN,tr|F6TLX2|F6TLX2_HUMAN" 3 1360.8057 0.8 6093 18434 2 1360.804642 681.4101 Glyoxalase domain-containing protein 4 OS=Homo sapiens OX=9606 GN=GLOD4 PE=1 SV=1 5.84 3549.9 - 582337 - - - -0.7907 - 2.432 0.545 - 691.5 1 2 0 -0.0011 13 0 0 0 5.22E+06 6.53E+06 - - - 5.3469 0.9985 221125_WJC_METTL3_EV_vs_WT_F01.18436.18436.2 0.00214 14-Aug R.AEWLLAVR[166.11].S sp|Q9NRN7|ADPPT_HUMAN 1 966.5526 0.59 6095 18436 2 966.554973 484.2836 L-aminoadipate-semialdehyde dehydrogenase-phosphopantetheinyl transferase OS=Homo sapiens OX=9606 GN=AASDHPPT PE=1 SV=2 6.05 3550.1 - 485137 - - - 2.4334 - 1.65 0.341 - 316.5 1 2 0 0.0024 8 0 0 0 1.12E+07 1.89E+07 - - - 3.0692 0.9624 221125_WJC_METTL3_EV_vs_WT_F01.18437.18437.2 6.93E-05 20-Oct F.PDTPLALDANK[136.11].K sp|Q12906|ILF3_HUMAN 1 1161.6121 0.43 6096 18437 2 1161.614711 581.8133 Interleukin enhancer-binding factor 3 OS=Homo sapiens OX=9606 GN=ILF3 PE=1 SV=3 4.21 3550.3 - 469942 - - - 2.2452 - 1.906 0.415 - 277.3 1 1 0 0.0026 11 0 0 0 3.17E+06 7.44E+06 - - - 3.8503 0.9996 221125_WJC_METTL3_EV_vs_WT_F01.18443.18443.2 0.0389 14-Sep K.TVALWDLR[166.11].N "sp|Q09028|RBBP4_HUMAN,sp|Q16576|RBBP7_HUMAN,tr|H0YCT5|H0YCT5_HUMAN,tr|H0YDK2|H0YDK2_HUMAN,tr|Q5JP02|Q5JP02_HUMAN,tr|H0YEU5|H0YEU5_HUMAN,tr|H0YF10|H0YF10_HUMAN,tr|E9PC52|E9PC52_HUMAN" 8 982.5475 1.38 6100 18443 2 982.548061 492.281 Histone-binding protein RBBP4 OS=Homo sapiens OX=9606 GN=RBBP4 PE=1 SV=3 5.5 3551 - 4.31E+06 - - - 0.5343 - 1.908 0.332 - 283.1 1 2 0 0.0005 8 0 0 0 5.65E+08 4.10E+08 - - - 3.4415 0.9983 221125_WJC_METTL3_EV_vs_WT_F01.18444.18444.2 1.59 14-Jul K.TVALWDLR.N "sp|Q09028|RBBP4_HUMAN,sp|Q16576|RBBP7_HUMAN,tr|H0YCT5|H0YCT5_HUMAN,tr|H0YDK2|H0YDK2_HUMAN,tr|Q5JP02|Q5JP02_HUMAN,tr|H0YEU5|H0YEU5_HUMAN,tr|H0YF10|H0YF10_HUMAN,tr|E9PC52|E9PC52_HUMAN" 8 972.5393 1.38 6101 18444 2 972.538872 487.2769 Histone-binding protein RBBP4 OS=Homo sapiens OX=9606 GN=RBBP4 PE=1 SV=3 5.5 3551.1 - 3.65E+06 - - - -0.4051 - 1.405 0.252 - 190.8 1 2 0 -0.0004 8 0 0 0 5.65E+08 4.10E+08 - - - 1.9277 0.9996 221125_WJC_METTL3_EV_vs_WT_F01.18450.18450.2 0.00737 24-Aug R.FFQELPGSDPVFK.A "sp|Q6P996|PDXD1_HUMAN,sp|Q6P474|PDXD2_HUMAN,tr|Q86XE2|Q86XE2_HUMAN,tr|H3BND4|H3BND4_HUMAN,tr|Q6XYB5|Q6XYB5_HUMAN" 5 1509.7504 8.91 6107 18450 2 1509.750117 755.8825 Pyridoxal-dependent decarboxylase domain-containing protein 1 OS=Homo sapiens OX=9606 GN=PDXDC1 PE=1 SV=2 4.37 3551.7 - 220635 - - - -0.1749 - 1.508 0.417 - 115.4 1 2 0 -0.0003 13 0 0 0 2.57E+06 2.88E+05 - - - 3.1752 0.9863 221125_WJC_METTL3_EV_vs_WT_F01.18451.18451.2 0.000113 26-Sep R.VVYGGGAAEISC[160.03]AL.A "sp|P48643|TCPE_HUMAN,tr|E9PCA1|E9PCA1_HUMAN,tr|B7ZAR1|B7ZAR1_HUMAN,tr|E7ENZ3|E7ENZ3_HUMAN" 4 1365.6599 - 6108 18451 2 1365.661549 683.8372 T-complex protein 1 subunit epsilon OS=Homo sapiens OX=9606 GN=CCT5 PE=1 SV=1 4 3551.8 - 152448 - - - 1.2426 - 1.758 0.54 - 242.9 1 1 0 0.0017 14 0 0 0 - - - - - 4.4447 0.9996 221125_WJC_METTL3_EV_vs_WT_F01.18454.18454.2 0.349 18-Nov K.AIAINTFLPK[136.11].N sp|Q92615|LAR4B_HUMAN 1 1094.6579 1.2 6109 18454 2 1094.657438 548.3362 La-related protein 4B OS=Homo sapiens OX=9606 GN=LARP4B PE=1 SV=3 8.8 3552.2 - 6.66E+06 - - - -0.4504 - 2.274 0.252 - 340.1 1 2 0 -0.0005 10 0 0 0 7.22E+07 6.04E+07 - - - 3.1953 0.9939 221125_WJC_METTL3_EV_vs_WT_F01.18457.18457.2 1.2 12-Jul R.YILDYLR.D "sp|Q96CX2|KCD12_HUMAN,sp|Q68DU8|KCD16_HUMAN" 2 954.5175 1.02 6112 18457 2 954.517981 478.266 BTB\POZ domain-containing protein KCTD12 OS=Homo sapiens OX=9606 GN=KCTD12 PE=1 SV=1 5.83 3552.4 - 1.41E+06 - - - 0.5374 - 1.467 0.105 - 181.3 1 2 0 0.0005 7 0 0 0 1.32E+07 1.30E+07 - - - 1.0306 0.9993 221125_WJC_METTL3_EV_vs_WT_F01.18458.18458.2 0.0416 18-Oct R.ILVATNLFGR[166.11].G "sp|Q13838|DX39B_HUMAN,sp|O00148|DX39A_HUMAN,tr|H0Y400|H0Y400_HUMAN,tr|Q5STU3|Q5STU3_HUMAN,tr|A0A0G2JJZ9|A0A0G2JJZ9_HUMAN,tr|A0A140T9X3|A0A140T9X3_HUMAN" 6 1112.6581 1.11 6113 18458 2 1112.660039 557.3364 Spliceosome RNA helicase DDX39B OS=Homo sapiens OX=9606 GN=DDX39B PE=1 SV=1 9.75 3552.5 - 1.41E+06 - - - 1.6986 - 2.066 0.309 - 256.6 1 2 0 0.0019 10 0 0 0 3.62E+08 3.27E+08 - - - 3.3481 0.9994 221125_WJC_METTL3_EV_vs_WT_F01.18459.18459.2 3.57E-06 18-Nov K.LYGEFADPFK.L "sp|O75694|NU155_HUMAN,tr|E9PF10|E9PF10_HUMAN" 2 1185.5706 1.01 6114 18459 2 1185.574324 593.7926 Nuclear pore complex protein Nup155 OS=Homo sapiens OX=9606 GN=NUP155 PE=1 SV=1 4.37 3552.6 - 966722 - - - 3.1192 - 1.958 0.517 - 347.8 1 2 0 0.0037 10 0 0 0 1.43E+07 1.42E+07 - - - 4.7339 0.9999 221125_WJC_METTL3_EV_vs_WT_F01.18460.18460.2 2.07E-05 18-Dec R.FEELC[160.03]SDLFR[166.11].S "sp|P48741|HSP77_HUMAN,sp|P0DMV8|HS71A_HUMAN,sp|P0DMV9|HS71B_HUMAN,sp|P17066|HSP76_HUMAN,tr|V9GZ37|V9GZ37_HUMAN,tr|A0A0G2JIW1|A0A0G2JIW1_HUMAN" 6 1324.5997 0.08 6115 18460 2 1324.599513 663.3071 Putative heat shock 70 kDa protein 7 OS=Homo sapiens OX=9606 GN=HSPA7 PE=5 SV=2 4.14 3552.7 - 812699 - - - -0.1472 - 2.379 0.552 - 575.9 1 2 0 -0.0002 10 0 0 0 3.80E+06 4.84E+07 - - - 5.5372 0.9998 221125_WJC_METTL3_EV_vs_WT_F01.18465.18465.2 0.012 18-Oct R.ILVATNLFGR.G "sp|Q13838|DX39B_HUMAN,sp|O00148|DX39A_HUMAN,tr|H0Y400|H0Y400_HUMAN,tr|Q5STU3|Q5STU3_HUMAN,tr|A0A0G2JJZ9|A0A0G2JJZ9_HUMAN,tr|A0A140T9X3|A0A140T9X3_HUMAN" 6 1102.6499 1.11 6118 18465 2 1102.648804 552.3322 Spliceosome RNA helicase DDX39B OS=Homo sapiens OX=9606 GN=DDX39B PE=1 SV=1 9.75 3553.4 - 3.97E+06 - - - -0.9749 - 2.082 0.457 - 305.8 1 2 0 -0.0011 10 0 0 0 3.62E+08 3.27E+08 - - - 4.463 0.9946 221125_WJC_METTL3_EV_vs_WT_F01.18466.18466.2 0.385 12-Aug R.YILDYLR[166.11].D "sp|Q96CX2|KCD12_HUMAN,sp|Q68DU8|KCD16_HUMAN" 2 964.5257 1.05 6119 18466 2 964.525722 483.2701 BTB\POZ domain-containing protein KCTD12 OS=Homo sapiens OX=9606 GN=KCTD12 PE=1 SV=1 5.83 3553.5 - 1.71E+06 - - - -0.0166 - 1.437 0.116 - 276.8 1 2 0 0 7 0 0 0 1.37E+07 1.30E+07 - - - 1.0466 0.9997 221125_WJC_METTL3_EV_vs_WT_F01.18467.18467.2 0.00895 16-Aug R.SLDLLGLEK[136.11].L "sp|O95551|TYDP2_HUMAN,tr|X6R5A3|X6R5A3_HUMAN" 2 994.579 0.39 6120 18467 2 994.579074 498.2968 Tyrosyl-DNA phosphodiesterase 2 OS=Homo sapiens OX=9606 GN=TDP2 PE=1 SV=1 4.37 3553.5 - 1.50E+06 - - - 0.0623 - 1.656 0.409 - 168.9 1 2 0 0.0001 9 0 0 0 6.31E+06 1.63E+07 - - - 3.5211 0.9999 221125_WJC_METTL3_EV_vs_WT_F01.18469.18469.2 3.35E-05 26-Dec K.YILVTGGVISGIGK[136.11].G "sp|P17812|PYRG1_HUMAN,sp|Q9NRF8|PYRG2_HUMAN,tr|A0A3B3ITH9|A0A3B3ITH9_HUMAN,tr|A0A3B3ITF6|A0A3B3ITF6_HUMAN,tr|A0A3B3IRQ8|A0A3B3IRQ8_HUMAN,tr|A0A3B3ITB8|A0A3B3ITB8_HUMAN,tr|A0A3B3IRI2|A0A3B3IRI2_HUMAN" 7 1383.8217 0.57 6122 18469 2 1383.821525 692.9181 CTP synthase 1 OS=Homo sapiens OX=9606 GN=CTPS1 PE=1 SV=2 8.59 3553.8 - 429340 - - - -0.1279 - 2.183 0.535 - 352.6 1 2 0 -0.0002 14 0 0 0 2.85E+06 4.98E+06 - - - 4.9516 0.9987 221125_WJC_METTL3_EV_vs_WT_F01.18473.18473.2 0.00808 22-Sep K.IIATVLMTEDIK[136.11].L "sp|Q04637|IF4G1_HUMAN,tr|C9J2Z7|C9J2Z7_HUMAN,tr|E7EUU4|E7EUU4_HUMAN,tr|E9PGM1|E9PGM1_HUMAN,tr|C9J6B6|C9J6B6_HUMAN,tr|E7EX73|E7EX73_HUMAN,tr|C9K073|C9K073_HUMAN,tr|A0A7I2Y1C3|A0A7I2Y1C3_HUMAN,tr|C9JF13|C9JF13_HUMAN" 9 1353.7669 1.75 6126 18473 2 1353.76976 677.8907 Eukaryotic translation initiation factor 4 gamma 1 OS=Homo sapiens OX=9606 GN=EIF4G1 PE=1 SV=4 4.37 3554.3 - 244849 - - - 2.1207 - 1.635 0.354 - 196.9 1 2 0 0.0029 12 0 0 0 4.63E+06 2.64E+06 - - - 2.9483 0.7996 221125_WJC_METTL3_EV_vs_WT_F01.18474.18474.2 0.00805 12-Jul A.IYELLFK.E "sp|P46783|RS10_HUMAN,tr|A0A2R8Y6L3|A0A2R8Y6L3_HUMAN,tr|F6U211|F6U211_HUMAN,tr|A0A1W2PQS6|A0A1W2PQS6_HUMAN,tr|A0A2R8YFH6|A0A2R8YFH6_HUMAN,tr|A0A2R8Y7H1|A0A2R8Y7H1_HUMAN" 6 924.5321 1.21 6127 18474 2 924.530212 463.2733 40S ribosomal protein S10 OS=Homo sapiens OX=9606 GN=RPS10 PE=1 SV=1 6 3554.4 - 192076 - - - -1.9934 - 1.36 0.244 - 97.5 1 1 0 -0.0018 7 0 0 0 1.40E+06 1.15E+06 - - - 1.8169 0.9999 221125_WJC_METTL3_EV_vs_WT_F01.18478.18478.2 5.87E-09 15/26 R.ALMGSPQLVAAVVR.T "sp|P14923|PLAK_HUMAN,tr|C9JKY1|C9JKY1_HUMAN,tr|C9JK18|C9JK18_HUMAN,tr|C9JTX4|C9JTX4_HUMAN,tr|C9J826|C9J826_HUMAN" 5 1410.8017 3.22 6129 18478 2 1410.801169 706.4081 Junction plakoglobin OS=Homo sapiens OX=9606 GN=JUP PE=1 SV=3 9.79 3554.9 - 2.25E+06 - - - -0.3799 - 2.81 0.529 - 696.7 1 2 0 -0.0005 14 0 0 0 1.07E+08 3.33E+07 - - - 5.5407 1 221125_WJC_METTL3_EV_vs_WT_F01.18479.18479.2 3.10E-09 17/30 R.IINEPTAAAIAYGLDR.T "sp|P0DMV8|HS71A_HUMAN,sp|P0DMV9|HS71B_HUMAN,sp|P17066|HSP76_HUMAN,tr|A0A0G2JIW1|A0A0G2JIW1_HUMAN" 4 1686.8941 0.17 6130 18479 2 1686.894069 844.4543 Heat shock 70 kDa protein 1A OS=Homo sapiens OX=9606 GN=HSPA1A PE=1 SV=1 4.37 3555.1 - 1.21E+06 - - - -0.0095 - 3.258 0.579 - 875.5 1 2 0 0 16 0 0 0 3.59E+08 2.14E+09 - - - 6.2213 0.8903 221125_WJC_METTL3_EV_vs_WT_F01.18483.18483.2 11.2 16-Aug R.GLNIILISR[166.11].N "sp|Q3SXM5|HSDL1_HUMAN,tr|H3BQI7|H3BQI7_HUMAN,tr|H3BT52|H3BT52_HUMAN" 3 1007.6367 0.8 6134 18483 2 1007.636869 504.8256 Inactive hydroxysteroid dehydrogenase-like protein 1 OS=Homo sapiens OX=9606 GN=HSDL1 PE=1 SV=3 9.75 3555.5 - 544570 - - - 0.1826 - 1.08 0 - 89.5 3 2 0 0.0002 9 0 0 0 3.78E+06 4.75E+06 - - - -0.9495 0.9971 221125_WJC_METTL3_EV_vs_WT_F01.18487.18487.2 0.0345 14-Jun K.GPLDNFLR.N "sp|Q13111|CAF1A_HUMAN,tr|K7EJF1|K7EJF1_HUMAN" 2 930.4923 1.39 6138 18487 2 930.493666 466.2534 Chromatin assembly factor 1 subunit A OS=Homo sapiens OX=9606 GN=CHAF1A PE=1 SV=3 5.84 3556 - 356687 - - - 1.4508 - 1.286 0.284 - 87.9 1 2 0 0.0014 8 0 0 0 4.02E+06 2.89E+06 - - - 1.8968 0.9984 221125_WJC_METTL3_EV_vs_WT_F01.18494.18494.2 0.0419 18-Aug R.LWTPPEDYRL.- "sp|Q9BYD1|RM13_HUMAN,tr|H0YAX3|H0YAX3_HUMAN" 2 1288.6452 1.67 6144 18494 2 1288.644351 645.3299 "39S ribosomal protein L13, mitochondrial OS=Homo sapiens OX=9606 GN=MRPL13 PE=1 SV=1" 4.37 3557.1 - 909843 - - - -0.6495 - 1.612 0.226 - 195.3 1 2 0 -0.0008 10 0 0 0 2.87E+07 1.72E+07 - - - 2.0428 1 221125_WJC_METTL3_EV_vs_WT_F01.18496.18496.2 1.29E-10 16/30 R.IINEPTAAAIAYGLDR[166.11].T "sp|P0DMV8|HS71A_HUMAN,sp|P0DMV9|HS71B_HUMAN,sp|P17066|HSP76_HUMAN,tr|A0A0G2JIW1|A0A0G2JIW1_HUMAN" 4 1696.9024 0.17 6145 18496 2 1696.899729 849.4585 Heat shock 70 kDa protein 1A OS=Homo sapiens OX=9606 GN=HSPA1A PE=1 SV=1 4.37 3557.3 - 5.28E+07 - - - -1.5475 - 3.283 0.631 - 767.2 1 2 0 -0.0026 16 0 0 0 3.54E+08 2.13E+09 - - - 6.6234 1 221125_WJC_METTL3_EV_vs_WT_F01.18497.18497.3 7.18E-07 15/60 R.IINEPTAAAIAYGLDR.T "sp|P0DMV8|HS71A_HUMAN,sp|P0DMV9|HS71B_HUMAN,sp|P17066|HSP76_HUMAN,tr|A0A0G2JIW1|A0A0G2JIW1_HUMAN" 4 1686.8941 0.16 6146 18497 3 1686.897459 563.3053 Heat shock 70 kDa protein 1A OS=Homo sapiens OX=9606 GN=HSPA1A PE=1 SV=1 4.37 3557.3 - 7.21E+06 - - - 2.0001 - 3.218 0.532 - 311.8 1 2 0 0.0034 16 0 0 0 2.68E+08 1.65E+09 - - - 7.4692 1 221125_WJC_METTL3_EV_vs_WT_F01.18498.18498.3 3.24E-11 17/60 R.IINEPTAAAIAYGLDR[166.11].T "sp|P0DMV8|HS71A_HUMAN,sp|P0DMV9|HS71B_HUMAN,sp|P17066|HSP76_HUMAN,tr|A0A0G2JIW1|A0A0G2JIW1_HUMAN" 4 1696.9024 0.16 6147 18498 3 1696.900578 566.6414 Heat shock 70 kDa protein 1A OS=Homo sapiens OX=9606 GN=HSPA1A PE=1 SV=1 4.37 3557.3 - 5.56E+07 - - - -1.0472 - 3.539 0.629 - 307.8 1 2 0 -0.0018 16 0 0 0 2.67E+08 1.65E+09 - - - 8.7951 0.9974 221125_WJC_METTL3_EV_vs_WT_F01.18499.18499.2 1.46 16-Nov K.GLLNAIVIK.E sp|P04181|OAT_HUMAN 1 939.6117 1.12 6148 18499 2 939.611144 470.8131 "Ornithine aminotransferase, mitochondrial OS=Homo sapiens OX=9606 GN=OAT PE=1 SV=1" 8.75 3557.4 - 2.27E+06 - - - -0.5949 - 1.638 0.155 - 236 1 2 0 -0.0006 9 0 0 0 2.97E+07 2.65E+07 - - - 1.6133 0.9992 221125_WJC_METTL3_EV_vs_WT_F01.18500.18500.2 0.00993 16-Sep K.GLLNAIVIK[136.11].E sp|P04181|OAT_HUMAN 1 947.6259 1.12 6149 18500 2 947.62538 474.8202 "Ornithine aminotransferase, mitochondrial OS=Homo sapiens OX=9606 GN=OAT PE=1 SV=1" 8.75 3557.5 - 2.00E+06 - - - -0.5519 - 1.898 0.232 - 184.3 1 2 0 -0.0005 9 0 0 0 2.97E+07 2.65E+07 - - - 2.6083 0.9772 221125_WJC_METTL3_EV_vs_WT_F01.18507.18507.2 0.000658 Nov-36 K.LLAAYPGASGLGSAAAAAA.A sp|Q9H7S9|ZN703_HUMAN 1 1601.8413 - 6156 18507 2 1601.841615 801.9279 Zinc finger protein 703 OS=Homo sapiens OX=9606 GN=ZNF703 PE=1 SV=1 5.52 3558.2 - 859055 - - - 0.1829 - 2.04 0.34 - 284 1 1 0 0.0003 19 0 0 0 - - - - - 3.305 0.9992 221125_WJC_METTL3_EV_vs_WT_F01.18508.18508.2 0.0164 14-Sep R.LGAFFLER[166.11].S sp|Q9BRX5|PSF3_HUMAN 1 961.5261 0.7 6157 18508 2 961.528141 481.7703 DNA replication complex GINS protein PSF3 OS=Homo sapiens OX=9606 GN=GINS3 PE=1 SV=1 6 3558.3 - 700060 - - - 2.1518 - 1.93 0.334 - 223.2 1 2 0 0.0021 8 0 0 0 7.57E+06 1.08E+07 - - - 3.4903 0.9927 221125_WJC_METTL3_EV_vs_WT_F01.18512.18512.2 0.382 18-Jun R.LWTPPEDYR[166.11]L.- "sp|Q9BYD1|RM13_HUMAN,tr|H0YAX3|H0YAX3_HUMAN" 2 1298.6535 1.63 6161 18512 2 1298.651519 650.334 "39S ribosomal protein L13, mitochondrial OS=Homo sapiens OX=9606 GN=MRPL13 PE=1 SV=1" 4.37 3558.8 - 607500 - - - -1.4931 - 1.508 0.129 - 139.5 1 2 0 -0.0019 10 0 0 0 2.76E+07 1.70E+07 - - - 1.1398 0.9999 221125_WJC_METTL3_EV_vs_WT_F01.18513.18513.2 2.39E-05 20-Nov K.FLC[160.03]YLSQAGFR[166.11].V sp|Q7Z2T5|TRM1L_HUMAN 1 1370.6681 0.39 6162 18513 2 1370.666213 686.3413 TRMT1-like protein OS=Homo sapiens OX=9606 GN=TRMT1L PE=1 SV=2 8.22 3559 - 420029 - - - -1.349 - 2.299 0.52 - 449.5 1 2 0 -0.0018 11 0 0 0 2.30E+06 5.88E+06 - - - 5.1332 0.9297 221125_WJC_METTL3_EV_vs_WT_F01.18514.18514.2 0.234 16-Sep K.FSPTDFLAK.M "sp|P42704|LPPRC_HUMAN,tr|A0A804HI14|A0A804HI14_HUMAN,tr|A0A804HL40|A0A804HL40_HUMAN,tr|A0A804HKJ0|A0A804HKJ0_HUMAN,tr|A0A804HKR3|A0A804HKR3_HUMAN,tr|A0A0C4DG06|A0A0C4DG06_HUMAN,tr|A0A804HIN4|A0A804HIN4_HUMAN,tr|A0A804HLG8|A0A804HLG8_HUMAN,tr|A0A804HIV5|A0A804HIV5_HUMAN,tr|A0A804HHY9|A0A804HHY9_HUMAN,tr|A0A804HJH8|A0A804HJH8_HUMAN,tr|B8ZZ38|B8ZZ38_HUMAN,tr|A0A804HI40|A0A804HI40_HUMAN,tr|A0A804HJZ1|A0A804HJZ1_HUMAN,tr|C9JCA9|C9JCA9_HUMAN,tr|A0A804HIQ7|A0A804HIQ7_HUMAN,tr|A0A804HK30|A0A804HK30_HUMAN,tr|A0A804HKI2|A0A804HKI2_HUMAN,tr|A0A804HKR5|A0A804HKR5_HUMAN,tr|A0A804HKX0|A0A804HKX0_HUMAN,tr|A0A804HIG4|A0A804HIG4_HUMAN,tr|A0A804HK02|A0A804HK02_HUMAN" 22 1024.5229 0.87 6163 18514 2 1024.527138 513.2687 "Leucine-rich PPR motif-containing protein, mitochondrial OS=Homo sapiens OX=9606 GN=LRPPRC PE=1 SV=3" 5.84 3559.1 - 376750 - - - 4.0907 - 1.286 0.144 - 169 1 2 0 0.0042 9 0 0 0 5.29E+06 6.07E+06 - - - 0.831 0.8455 221125_WJC_METTL3_EV_vs_WT_F01.18518.18518.2 4.92 16-Jul K.LLQDFFNGR[166.11].D "sp|P0DMV8|HS71A_HUMAN,sp|P0DMV9|HS71B_HUMAN,tr|V9GZ37|V9GZ37_HUMAN,tr|A0A0G2JIW1|A0A0G2JIW1_HUMAN" 4 1118.5748 0.05 6166 18518 2 1118.577554 560.2947 Heat shock 70 kDa protein 1A OS=Homo sapiens OX=9606 GN=HSPA1A PE=1 SV=1 5.84 3559.5 - 609377 - - - 2.4504 - 1.039 0.047 - 64.1 1 2 0 0.0027 9 0 0 0 9.89E+05 2.17E+07 - - - -0.502 0.9998 221125_WJC_METTL3_EV_vs_WT_F01.18519.18519.2 0.00442 18-Oct R.FLLQDTVELR.E "sp|P78344|IF4G2_HUMAN,tr|H0Y3P2|H0Y3P2_HUMAN,tr|H0YCH5|H0YCH5_HUMAN,tr|D3DQV9|D3DQV9_HUMAN" 4 1232.6765 1.93 6167 18519 2 1232.675567 617.3455 Eukaryotic translation initiation factor 4 gamma 2 OS=Homo sapiens OX=9606 GN=EIF4G2 PE=1 SV=1 4.37 3559.6 - 6.01E+06 - - - -0.7472 - 2.295 0.391 - 387.2 1 2 0 -0.0009 10 0 0 0 1.95E+08 1.01E+08 - - - 4.2475 0.9313 221125_WJC_METTL3_EV_vs_WT_F01.18520.18520.3 0.0693 Sep-60 R.LIDAGHSEAATIAEWK[136.11].D "sp|P11277|SPTB1_HUMAN,tr|H0YJE6|H0YJE6_HUMAN" 2 1718.8719 0.02 6168 18520 3 1718.87941 573.9646 "Spectrin beta chain, erythrocytic OS=Homo sapiens OX=9606 GN=SPTB PE=1 SV=5" 4.65 3559.6 - 5.82E+06 - - - 4.3691 - 1.802 0.19 - 56.5 2 2 0 0.0075 16 0 0 0 1.93E+06 8.93E+07 - - - 2.0279 0.9999 221125_WJC_METTL3_EV_vs_WT_F01.18521.18521.2 0.11 18-Nov R.FLLQDTVELR[166.11].E "sp|P78344|IF4G2_HUMAN,tr|H0Y3P2|H0Y3P2_HUMAN,tr|H0YCH5|H0YCH5_HUMAN,tr|D3DQV9|D3DQV9_HUMAN" 4 1242.6848 1.97 6169 18521 2 1242.684585 622.3497 Eukaryotic translation initiation factor 4 gamma 2 OS=Homo sapiens OX=9606 GN=EIF4G2 PE=1 SV=1 4.37 3559.7 - 3.30E+06 - - - -0.1392 - 2.228 0.443 - 525 1 2 0 -0.0002 10 0 0 0 1.95E+08 9.87E+07 - - - 4.5491 0.9964 221125_WJC_METTL3_EV_vs_WT_F01.18525.18525.2 0.118 22-Aug R.QVVNGLMLGQAR[166.11].L tr|H0YHV6|H0YHV6_HUMAN 1 1294.7055 0.17 6173 18525 2 1294.703516 648.36 WD repeat-containing protein 90 (Fragment) OS=Homo sapiens OX=9606 GN=WDR90 PE=4 SV=1 9.75 3560.1 - 1.39E+06 - - - -1.5401 - 1.709 0.168 - 74 1 2 0 -0.002 12 0 0 0 5.76E+06 3.33E+07 - - - 1.6913 0.9998 221125_WJC_METTL3_EV_vs_WT_F01.18528.18528.2 0.0194 13/22 R.IPELAINPLGDR.L "sp|Q99653|CHP1_HUMAN,tr|H0YLY7|H0YLY7_HUMAN,tr|F5GX29|F5GX29_HUMAN,tr|H0YKE7|H0YKE7_HUMAN,tr|H0YNG9|H0YNG9_HUMAN" 5 1306.7245 2.72 6176 18528 2 1306.723282 654.3695 Calcineurin B homologous protein 1 OS=Homo sapiens OX=9606 GN=CHP1 PE=1 SV=3 4.37 3560.4 - 666315 - - - -0.9329 - 2.379 0.375 - 696.1 1 2 0 -0.0012 12 0 0 0 8.01E+06 2.94E+06 - - - 4.0908 0.9883 221125_WJC_METTL3_EV_vs_WT_F01.18536.18536.2 4.91E-05 22-Nov E.PTAAAIAYGLDR[166.11].T "sp|P0DMV8|HS71A_HUMAN,sp|P0DMV9|HS71B_HUMAN,sp|P17066|HSP76_HUMAN,tr|A0A0G2JIW1|A0A0G2JIW1_HUMAN" 4 1227.6487 0.03 6182 18536 2 1227.646938 614.8316 Heat shock 70 kDa protein 1A OS=Homo sapiens OX=9606 GN=HSPA1A PE=1 SV=1 6.26 3561.3 - 1.26E+06 - - - -1.441 - 2.509 0.44 - 173.7 1 1 0 -0.0018 12 0 0 0 4.32E+05 1.53E+07 - - - 4.7107 0.9991 221125_WJC_METTL3_EV_vs_WT_F01.18537.18537.2 0.000425 20-Oct K.FLIPDYNDEIR.Q "sp|O75525|KHDR3_HUMAN,tr|H0YAQ3|H0YAQ3_HUMAN,tr|E5RJZ9|E5RJZ9_HUMAN,tr|H0YAQ1|H0YAQ1_HUMAN,tr|E5RG12|E5RG12_HUMAN" 5 1393.6878 1.4 6183 18537 2 1393.691003 697.8512 "KH domain-containing, RNA-binding, signal transduction-associated protein 3 OS=Homo sapiens OX=9606 GN=KHDRBS3 PE=1 SV=1" 4.03 3561.4 - 1.35E+06 - - - 2.3119 - 1.692 0.415 - 310.6 1 2 0 0.0032 11 0 0 0 1.40E+07 1.00E+07 - - - 3.5279 0.9993 221125_WJC_METTL3_EV_vs_WT_F01.18538.18538.2 0.199 16-Oct R.LDALLAELR[166.11].A sp|Q96L58|B3GT6_HUMAN 1 1022.6 1.07 6184 18538 2 1022.601428 512.3073 "Beta-1,3-galactosyltransferase 6 OS=Homo sapiens OX=9606 GN=B3GALT6 PE=1 SV=2" 4.37 3561.6 - 833462 - - - 1.4297 - 2.475 0.199 - 416.8 1 2 0 0.0015 9 0 0 0 1.86E+07 1.73E+07 - - - 3.1322 0.9921 221125_WJC_METTL3_EV_vs_WT_F01.18539.18539.2 2.79E-08 14/26 L.NEPTAAAIAYGLDR[166.11].T "sp|P0DMV8|HS71A_HUMAN,sp|P0DMV9|HS71B_HUMAN,sp|P17066|HSP76_HUMAN,tr|A0A0G2JIW1|A0A0G2JIW1_HUMAN" 4 1470.7342 0.1 6185 18539 2 1470.735478 736.3744 Heat shock 70 kDa protein 1A OS=Homo sapiens OX=9606 GN=HSPA1A PE=1 SV=1 4.37 3561.7 - 721401 - - - 0.8506 - 2.807 0.468 - 740.6 1 1 0 0.0013 14 0 0 0 8.88E+05 8.98E+06 - - - 5.0873 0.9997 221125_WJC_METTL3_EV_vs_WT_F01.18544.18544.2 0.000348 22-Oct R.SLVPAAELLESR.V "sp|Q15149|PLEC_HUMAN,tr|H0YDN1|H0YDN1_HUMAN" 2 1283.7085 2.27 6188 18544 2 1283.709346 642.8615 Plectin OS=Homo sapiens OX=9606 GN=PLEC PE=1 SV=3 4.53 3562.3 - 425795 - - - 0.6466 - 1.999 0.418 - 340 1 2 0 0.0008 12 0 0 0 2.77E+07 1.22E+07 - - - 3.9506 0.9998 221125_WJC_METTL3_EV_vs_WT_F01.18546.18546.2 0.00578 18-Dec R.IPDEIIDMVK.E "sp|Q9Y4Z0|LSM4_HUMAN,tr|U3KQK1|U3KQK1_HUMAN,tr|V9GZ56|V9GZ56_HUMAN" 3 1171.6159 1.93 6190 18546 2 1171.616975 586.8152 U6 snRNA-associated Sm-like protein LSm4 OS=Homo sapiens OX=9606 GN=LSM4 PE=1 SV=1 4.03 3562.4 - 2.87E+06 - - - 0.95 - 2.181 0.471 - 386.7 1 2 0 0.0011 10 0 0 0 1.20E+08 6.22E+07 - - - 4.6961 0.9998 221125_WJC_METTL3_EV_vs_WT_F01.18552.18552.2 0.0123 20-Sep K.VANVSLLALYK[136.11].G sp|P62266|RS23_HUMAN 1 1197.7213 0.95 6194 18552 2 1197.720039 599.8679 40S ribosomal protein S23 OS=Homo sapiens OX=9606 GN=RPS23 PE=1 SV=3 8.56 3563.2 - 2.70E+06 - - - -1.0194 - 2.282 0.405 - 291.6 1 2 0 -0.0012 11 0 0 0 5.85E+08 6.14E+08 - - - 4.2639 0.9952 221125_WJC_METTL3_EV_vs_WT_F01.18554.18554.2 0.411 14-Jul K.FIIPQIVK[136.11].Y "sp|P07195|LDHB_HUMAN,tr|A8MW50|A8MW50_HUMAN,tr|A0A3B3IS95|A0A3B3IS95_HUMAN,tr|C9J7H8|C9J7H8_HUMAN,tr|A0A5F9ZHM4|A0A5F9ZHM4_HUMAN" 5 964.6201 0.79 6196 18554 2 964.619168 483.3173 L-lactate dehydrogenase B chain OS=Homo sapiens OX=9606 GN=LDHB PE=1 SV=2 8.75 3563.4 - 1.25E+06 - - - -0.9548 - 1.244 0.21 - 161.3 1 2 0 -0.0009 8 0 0 0 2.18E+07 2.76E+07 - - - 1.2502 0.986 221125_WJC_METTL3_EV_vs_WT_F01.18555.18555.2 0.251 14-May K.LGTLFAFK[136.11].K sp|Q6F5E8|CARL2_HUMAN 1 903.5309 1.38 6197 18555 2 903.529728 452.7727 "Capping protein, Arp2\3 and myosin-I linker protein 2 OS=Homo sapiens OX=9606 GN=CARMIL2 PE=1 SV=2" 8.75 3563.5 - 672220 - - - -1.3414 - 1.183 0.182 - 48.6 4 2 0 -0.0012 8 0 0 0 1.20E+07 8.70E+06 - - - 0.6228 1 221125_WJC_METTL3_EV_vs_WT_F01.18556.18556.2 9.14E-08 22-Nov K.SLAMEMVLTGDR.L sp|P30084|ECHM_HUMAN 1 1321.637 1.22 6198 18556 2 1321.636234 661.8258 "Enoyl-CoA hydratase, mitochondrial OS=Homo sapiens OX=9606 GN=ECHS1 PE=1 SV=4" 4.37 3563.7 - 611174 - - - -0.5856 - 2.486 0.604 - 501.1 1 2 0 -0.0008 12 0 0 0 8.63E+06 7.07E+06 - - - 5.898 0.9996 221125_WJC_METTL3_EV_vs_WT_F01.18559.18559.2 0.00306 18-Oct K.AIAINTFLPK.N sp|Q92615|LAR4B_HUMAN 1 1086.6437 1.22 6200 18559 2 1086.642813 544.3291 La-related protein 4B OS=Homo sapiens OX=9606 GN=LARP4B PE=1 SV=3 8.8 3564 - 2.35E+07 - - - -0.8448 - 1.834 0.373 - 279.6 1 2 0 -0.0009 10 0 0 0 3.46E+08 2.84E+08 - - - 3.4886 0.9999 221125_WJC_METTL3_EV_vs_WT_F01.18562.18562.2 3.88E-05 16-Oct K.GFGFVSFER[166.11].H "sp|Q9H361|PABP3_HUMAN,sp|P11940|PABP1_HUMAN,tr|A0A7I2YQE4|A0A7I2YQE4_HUMAN,tr|A0A7I2V649|A0A7I2V649_HUMAN,tr|H0YAR2|H0YAR2_HUMAN,tr|E7ERJ7|E7ERJ7_HUMAN,tr|A0A7I2YQ88|A0A7I2YQ88_HUMAN,tr|A0A087WTT1|A0A087WTT1_HUMAN,tr|H0YAP2|H0YAP2_HUMAN,tr|A0A7I2YQ90|A0A7I2YQ90_HUMAN,tr|A0A7I2V4N4|A0A7I2V4N4_HUMAN,tr|E7EQV3|E7EQV3_HUMAN" 12 1054.5112 1.29 6202 18562 2 1054.510993 528.2629 Polyadenylate-binding protein 3 OS=Homo sapiens OX=9606 GN=PABPC3 PE=1 SV=2 6 3564.3 - 1.42E+06 - - - -0.1498 - 1.814 0.522 - 411.4 1 2 0 -0.0002 9 0 0 0 1.13E+09 8.81E+08 - - - 4.6194 0.9997 221125_WJC_METTL3_EV_vs_WT_F01.18563.18563.2 0.00655 16-Sep K.GFGFVSFER.H "sp|Q9H361|PABP3_HUMAN,sp|P11940|PABP1_HUMAN,tr|A0A7I2YQE4|A0A7I2YQE4_HUMAN,tr|A0A7I2V649|A0A7I2V649_HUMAN,tr|H0YAR2|H0YAR2_HUMAN,tr|E7ERJ7|E7ERJ7_HUMAN,tr|A0A7I2YQ88|A0A7I2YQ88_HUMAN,tr|A0A087WTT1|A0A087WTT1_HUMAN,tr|H0YAP2|H0YAP2_HUMAN,tr|A0A7I2YQ90|A0A7I2YQ90_HUMAN,tr|A0A7I2V4N4|A0A7I2V4N4_HUMAN,tr|E7EQV3|E7EQV3_HUMAN" 12 1044.5029 1.29 6203 18563 2 1044.501439 523.2587 Polyadenylate-binding protein 3 OS=Homo sapiens OX=9606 GN=PABPC3 PE=1 SV=2 6 3564.4 - 1.41E+06 - - - -1.3806 - 1.847 0.436 - 342.9 1 2 0 -0.0014 9 0 0 0 1.13E+09 8.81E+08 - - - 4.0359 0.9978 221125_WJC_METTL3_EV_vs_WT_F01.18564.18564.2 0.0914 14-Oct K.LLQQLFLK.A sp|Q9P287|BCCIP_HUMAN 1 1001.6274 0.65 6204 18564 2 1001.625557 501.821 BRCA2 and CDKN1A-interacting protein OS=Homo sapiens OX=9606 GN=BCCIP PE=1 SV=1 8.75 3564.5 - 1.10E+06 - - - -1.7931 - 1.587 0.241 - 193.4 1 2 0 -0.0018 8 0 0 0 1.53E+07 2.34E+07 - - - 2.2134 0.9988 221125_WJC_METTL3_EV_vs_WT_F01.18570.18570.2 1.65E-06 14/20 K.IGDFGLVTSLK[136.11].N "sp|P19525|E2AK2_HUMAN,tr|A0A7P0TAL9|A0A7P0TAL9_HUMAN,tr|A0A7P0TBA9|A0A7P0TBA9_HUMAN" 3 1156.6583 1.26 6208 18570 2 1156.654914 579.3364 "Interferon-induced, double-stranded RNA-activated protein kinase OS=Homo sapiens OX=9606 GN=EIF2AK2 PE=1 SV=2" 5.84 3565.3 - 1.10E+06 - - - -2.949 - 2.696 0.266 - 393.7 1 2 0 -0.0034 11 0 0 0 3.68E+07 2.91E+07 - - - 3.6876 0.9999 221125_WJC_METTL3_EV_vs_WT_F01.18571.18571.2 0.00119 13/18 R.IPDEIIDMVK[136.11].E "sp|Q9Y4Z0|LSM4_HUMAN,tr|U3KQK1|U3KQK1_HUMAN,tr|V9GZ56|V9GZ56_HUMAN" 3 1179.6301 1.93 6209 18571 2 1179.629527 590.8223 U6 snRNA-associated Sm-like protein LSm4 OS=Homo sapiens OX=9606 GN=LSM4 PE=1 SV=1 4.03 3565.3 - 4.07E+06 - - - -0.4535 - 2.356 0.421 - 619.3 1 2 0 -0.0005 10 0 0 0 1.20E+08 6.22E+07 - - - 4.5424 0.9995 221125_WJC_METTL3_EV_vs_WT_F01.18573.18573.2 0.000993 13/24 K.AEPLLGAPGELLK[136.11].Q sp|P17482|HXB9_HUMAN 1 1314.7639 1.37 6211 18573 2 1314.760801 658.3892 Homeobox protein Hox-B9 OS=Homo sapiens OX=9606 GN=HOXB9 PE=1 SV=2 4.53 3565.6 - 691976 - - - -2.3213 - 2.317 0.39 - 446.4 1 2 0 -0.0031 13 0 0 0 4.20E+07 3.08E+07 - - - 4.0772 0.9982 221125_WJC_METTL3_EV_vs_WT_F01.18576.18576.2 0.00114 24-Oct R.SLLINAVEASC[160.03]IR[166.11].T "sp|P32322|P5CR1_HUMAN,sp|Q96C36|P5CR2_HUMAN,tr|A0A087WZR9|A0A087WZR9_HUMAN,tr|J3QKT4|J3QKT4_HUMAN,tr|E2QRB3|E2QRB3_HUMAN,tr|A0A087WTV6|A0A087WTV6_HUMAN,tr|J3KR12|J3KR12_HUMAN" 7 1454.7791 0.56 6214 18576 2 1454.784215 728.3968 "Pyrroline-5-carboxylate reductase 1, mitochondrial OS=Homo sapiens OX=9606 GN=PYCR1 PE=1 SV=2" 5.72 3565.9 - 548220 - - - 3.5373 - 2.118 0.374 - 266.3 1 2 0 0.0051 13 0 0 0 3.36E+06 6.02E+06 - - - 3.7279 1 221125_WJC_METTL3_EV_vs_WT_F01.18579.18579.2 4.29E-10 30-Dec K.SYELPDGQVITIGNER.F "sp|Q6S8J3|POTEE_HUMAN,sp|P63261|ACTG_HUMAN,sp|P68133|ACTS_HUMAN,sp|P62736|ACTA_HUMAN,sp|Q9BYX7|ACTBM_HUMAN,sp|P68032|ACTC_HUMAN,sp|Q562R1|ACTBL_HUMAN,sp|P60709|ACTB_HUMAN,sp|P63267|ACTH_HUMAN,sp|A5A3E0|POTEF_HUMAN,tr|A0A804GS07|A0A804GS07_HUMAN,tr|E7EVS6|E7EVS6_HUMAN,tr|A0A6Q8PFE4|A0A6Q8PFE4_HUMAN,tr|A0A2R8YEA7|A0A2R8YEA7_HUMAN,tr|A0A804HKV3|A0A804HKV3_HUMAN,tr|A0A2R8Y793|A0A2R8Y793_HUMAN,tr|I3L4N8|I3L4N8_HUMAN,tr|A6NL76|A6NL76_HUMAN" 18 1789.8846 999 6217 18579 2 1789.878975 895.9496 POTE ankyrin domain family member E OS=Homo sapiens OX=9606 GN=POTEE PE=2 SV=3 4.14 3566.3 - 292731 - - - -3.1667 - 2.45 0.675 - 431.4 1 2 0 -0.0057 16 0 0 0 3.90E+06 0.00E+00 - - - 6.2278 0.9967 221125_WJC_METTL3_EV_vs_WT_F01.18581.18581.2 0.773 16-Aug R.YLDVSILGK[136.11].F sp|Q86U44|MTA70_HUMAN 1 1014.5841 0.23 6218 18581 2 1014.585082 508.2993 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 5.83 3566.6 - 2.45E+06 - - - 0.9699 - 1.584 0.168 - 154.3 1 2 0 0.001 9 0 0 0 6.78E+06 2.89E+07 - - - 1.6122 0.9999 221125_WJC_METTL3_EV_vs_WT_F01.18584.18584.2 0.000118 20-Nov K.VVVEQLNLLVK.R "sp|P34949|MPI_HUMAN,tr|H3BPB8|H3BPB8_HUMAN,tr|H3BP57|H3BP57_HUMAN,tr|H3BT48|H3BT48_HUMAN,tr|H3BUZ9|H3BUZ9_HUMAN,tr|H3BPP3|H3BPP3_HUMAN,tr|F5GX71|F5GX71_HUMAN,tr|H3BMZ9|H3BMZ9_HUMAN" 8 1252.7755 1.43 6221 18584 2 1252.775099 627.395 Mannose-6-phosphate isomerase OS=Homo sapiens OX=9606 GN=MPI PE=1 SV=2 5.97 3566.8 - 1.36E+06 - - - -0.2993 - 2.389 0.456 - 401.4 1 2 0 -0.0004 11 0 0 0 1.98E+07 1.38E+07 - - - 4.7648 0.9998 221125_WJC_METTL3_EV_vs_WT_F01.18585.18585.2 0.00108 20-Nov K.VVVEQLNLLVK[136.11].R "sp|P34949|MPI_HUMAN,tr|H3BPB8|H3BPB8_HUMAN,tr|H3BP57|H3BP57_HUMAN,tr|H3BT48|H3BT48_HUMAN,tr|H3BUZ9|H3BUZ9_HUMAN,tr|H3BPP3|H3BPP3_HUMAN,tr|F5GX71|F5GX71_HUMAN,tr|H3BMZ9|H3BMZ9_HUMAN" 8 1260.7897 1.43 6222 18585 2 1260.788396 631.4021 Mannose-6-phosphate isomerase OS=Homo sapiens OX=9606 GN=MPI PE=1 SV=2 5.97 3566.9 - 1.14E+06 - - - -1.0137 - 2.34 0.415 - 376.1 1 2 0 -0.0013 11 0 0 0 1.98E+07 1.38E+07 - - - 4.4056 0.9999 221125_WJC_METTL3_EV_vs_WT_F01.18586.18586.2 6.87E-06 15/24 K.AEPLLGAPGELLK.Q sp|P17482|HXB9_HUMAN 1 1306.7497 1.46 6223 18586 2 1306.750044 654.3821 Homeobox protein Hox-B9 OS=Homo sapiens OX=9606 GN=HOXB9 PE=1 SV=2 4.53 3567 - 1.09E+06 - - - 0.2992 - 2.589 0.541 - 629.9 1 2 0 0.0004 13 0 0 0 4.20E+07 2.88E+07 - - - 5.4782 0.991 221125_WJC_METTL3_EV_vs_WT_F01.18588.18588.2 0.746 12-Jul K.DLIIFDK.Q "sp|Q8NHQ1|CEP70_HUMAN,tr|C9J966|C9J966_HUMAN,tr|C9J710|C9J710_HUMAN,tr|C9JZ04|C9JZ04_HUMAN" 4 862.48 2.66 6225 18588 2 862.47992 432.2473 Centrosomal protein of 70 kDa OS=Homo sapiens OX=9606 GN=CEP70 PE=1 SV=2 4.21 3567.3 - 630017 - - - -0.1159 - 1.42 0.072 - 153.2 1 2 0 -0.0001 7 0 0 0 6.13E+06 2.30E+06 - - - 0.6838 0.8277 221125_WJC_METTL3_EV_vs_WT_F01.18592.18592.2 1.39 18-Mar K.WVAASC[160.03]MFTR[166.11].R sp|Q6TDP4|KLH17_HUMAN 1 1237.5612 0.13 6229 18592 2 1237.565059 619.7879 Kelch-like protein 17 OS=Homo sapiens OX=9606 GN=KLHL17 PE=1 SV=1 8.25 3567.7 - 760775 - - - 3.1554 - 1.028 0.18 - 19.6 41 2 0 0.0039 10 0 0 0 8.85E+05 6.83E+06 - - - -0.2741 0.9998 221125_WJC_METTL3_EV_vs_WT_F01.18594.18594.2 6.88E-06 24-Sep R.SLLINAVEASC[160.03]IR.T "sp|P32322|P5CR1_HUMAN,sp|Q96C36|P5CR2_HUMAN,tr|A0A087WZR9|A0A087WZR9_HUMAN,tr|J3QKT4|J3QKT4_HUMAN,tr|E2QRB3|E2QRB3_HUMAN,tr|A0A087WTV6|A0A087WTV6_HUMAN,tr|J3KR12|J3KR12_HUMAN" 7 1444.7708 0.56 6231 18594 2 1444.76829 723.3927 "Pyrroline-5-carboxylate reductase 1, mitochondrial OS=Homo sapiens OX=9606 GN=PYCR1 PE=1 SV=2" 5.72 3568 - 312175 - - - -1.7366 - 2.195 0.486 - 271.3 1 2 0 -0.0025 13 0 0 0 3.36E+06 6.02E+06 - - - 4.6476 0.9979 221125_WJC_METTL3_EV_vs_WT_F01.18595.18595.3 0.0496 Sep-40 K.VANVSLLALYK[136.11].G sp|P62266|RS23_HUMAN 1 1197.7213 1.12 6232 18595 3 1197.720474 400.2477 40S ribosomal protein S23 OS=Homo sapiens OX=9606 GN=RPS23 PE=1 SV=3 8.56 3568.1 - 297653 - - - -0.6562 - 1.769 0.237 - 84.8 1 2 0 -0.0008 11 0 0 0 5.66E+06 5.06E+06 - - - 2.8025 0.9997 221125_WJC_METTL3_EV_vs_WT_F01.18596.18596.3 0.000873 Sep-40 K.VANVSLLALYK.G sp|P62266|RS23_HUMAN 1 1189.7071 1.12 6233 18596 3 1189.705141 397.5763 40S ribosomal protein S23 OS=Homo sapiens OX=9606 GN=RPS23 PE=1 SV=3 8.56 3568.2 - 281802 - - - -1.613 - 1.931 0.356 - 94.6 1 2 0 -0.0019 11 0 0 0 5.66E+06 5.06E+06 - - - 4.3779 0.9993 221125_WJC_METTL3_EV_vs_WT_F01.18599.18599.2 0.0177 20-Nov R.IGFVGFPSVGK[136.11].S sp|Q9Y295|DRG1_HUMAN 1 1114.6266 0.51 6235 18599 2 1114.623975 558.3206 Developmentally-regulated GTP-binding protein 1 OS=Homo sapiens OX=9606 GN=DRG1 PE=1 SV=1 8.75 3568.6 - 3.41E+06 - - - -2.3829 - 2.039 0.395 - 336.8 1 2 0 -0.0027 11 0 0 0 6.23E+07 1.23E+08 - - - 3.885 0.9997 221125_WJC_METTL3_EV_vs_WT_F01.18605.18605.2 0.000588 16-Oct R.DITAEFLVK.S "sp|O60341|KDM1A_HUMAN,tr|R4GMQ1|R4GMQ1_HUMAN" 2 1034.5648 0.81 6240 18605 2 1034.565981 518.2897 Lysine-specific histone demethylase 1A OS=Homo sapiens OX=9606 GN=KDM1A PE=1 SV=2 4.37 3569.1 - 1.15E+06 - - - 1.1299 - 1.785 0.466 - 211 1 2 0 0.0012 9 0 0 0 1.95E+07 2.41E+07 - - - 4.1588 0.9977 221125_WJC_METTL3_EV_vs_WT_F01.18611.18611.2 0.000432 24-Jul K.LLLNLAENPAMTR[166.11].E sp|Q9UH62|ARMX3_HUMAN 1 1464.7998 -1 6246 18611 2 1464.796442 733.4072 Armadillo repeat-containing X-linked protein 3 OS=Homo sapiens OX=9606 GN=ARMCX3 PE=1 SV=1 6 3569.9 - 168933 - - - -2.2959 - 1.407 0.35 - 146 1 2 0 -0.0034 13 0 0 0 0.00E+00 0.00E+00 - - - 2.5014 0.9999 221125_WJC_METTL3_EV_vs_WT_F01.18614.18614.2 2.13E-05 18-Nov R.FEELNADLFR[166.11].G "sp|P54652|HSP72_HUMAN,sp|P11142|HSP7C_HUMAN,tr|E9PNE6|E9PNE6_HUMAN,tr|A8K7Q2|A8K7Q2_HUMAN,tr|E9PKE3|E9PKE3_HUMAN,tr|E9PN89|E9PN89_HUMAN" 6 1262.6171 0.17 6247 18614 2 1262.616941 632.3158 Heat shock-related 70 kDa protein 2 OS=Homo sapiens OX=9606 GN=HSPA2 PE=1 SV=1 4.14 3570.2 - 7.88E+06 - - - -0.1038 - 2.244 0.441 - 453.9 1 2 0 -0.0001 10 0 0 0 4.66E+08 2.75E+09 - - - 4.5543 0.9981 221125_WJC_METTL3_EV_vs_WT_F01.18620.18620.2 0.000112 20-Aug R.LAQPYVGVFLK[136.11].R "sp|P36776|LONM_HUMAN,tr|K7EQF8|K7EQF8_HUMAN,tr|K7EJE8|K7EJE8_HUMAN,tr|K7EKE6|K7EKE6_HUMAN" 4 1241.7263 1.46 6253 18620 2 1241.730785 621.8704 "Lon protease homolog, mitochondrial OS=Homo sapiens OX=9606 GN=LONP1 PE=1 SV=2" 8.59 3570.9 - 415966 - - - 3.5757 - 1.764 0.422 - 164.8 1 2 0 0.0044 11 0 0 0 9.58E+06 6.58E+06 - - - 3.6919 0.9999 221125_WJC_METTL3_EV_vs_WT_F01.18624.18624.2 4.55E-05 18-Nov R.FEELNADLFR.G "sp|P54652|HSP72_HUMAN,sp|P11142|HSP7C_HUMAN,tr|E9PNE6|E9PNE6_HUMAN,tr|A8K7Q2|A8K7Q2_HUMAN,tr|E9PKE3|E9PKE3_HUMAN,tr|E9PN89|E9PN89_HUMAN" 6 1252.6088 0.17 6255 18624 2 1252.606653 627.3117 Heat shock-related 70 kDa protein 2 OS=Homo sapiens OX=9606 GN=HSPA2 PE=1 SV=1 4.14 3571.4 - 3.71E+06 - - - -1.7156 - 2.269 0.586 - 463.3 1 2 0 -0.0021 10 0 0 0 4.66E+08 2.75E+09 - - - 5.6555 0.9897 221125_WJC_METTL3_EV_vs_WT_F01.18628.18628.2 0.0771 18-Aug R.FLITSNLELR.K tr|H0Y4V9|H0Y4V9_HUMAN 1 1204.6816 1.19 6259 18628 2 1204.68603 603.3481 La-related protein 4B (Fragment) OS=Homo sapiens OX=9606 GN=LARP4B PE=1 SV=1 6 3571.8 - 1.29E+06 - - - 3.6997 - 1.422 0.282 - 185.5 1 2 0 0.0045 10 0 0 0 1.55E+07 1.30E+07 - - - 2.1052 0.9831 221125_WJC_METTL3_EV_vs_WT_F01.18631.18631.2 0.151 16-Jun R.YQFTPAFLR.L "sp|Q13432|U119A_HUMAN,sp|A6NIH7|U119B_HUMAN,tr|K7EN86|K7EN86_HUMAN,tr|C9JSK0|C9JSK0_HUMAN,tr|K7EJU3|K7EJU3_HUMAN" 5 1141.592 0.96 6262 18631 2 1141.58759 571.8033 Protein unc-119 homolog A OS=Homo sapiens OX=9606 GN=UNC119 PE=1 SV=1 8.75 3572.1 - 432988 - - - -3.8893 - 1.333 0.26 - 85.3 1 2 0 -0.0044 9 0 0 0 2.49E+06 2.59E+06 - - - 1.7915 0.9269 221125_WJC_METTL3_EV_vs_WT_F01.18632.18632.2 1.32 22-Sep R.APGSGLALLPLK.L "sp|P58107|EPIPL_HUMAN,tr|A0A075B730|A0A075B730_HUMAN" 2 1135.6965 4.85 6263 18632 2 1135.694077 568.8555 Epiplakin OS=Homo sapiens OX=9606 GN=EPPK1 PE=1 SV=3 8.8 3572.3 - 379334 - - - -2.1291 - 1.047 0.093 - 107 1 2 0 -0.0024 12 0 0 0 1.37E+07 2.82E+06 - - - -0.152 0.9997 221125_WJC_METTL3_EV_vs_WT_F01.18634.18634.2 0.00287 16-Aug R.VSFELFADK[136.11].V "sp|P62937|PPIA_HUMAN,tr|C9J5S7|C9J5S7_HUMAN,tr|F8WE65|F8WE65_HUMAN,tr|A0A7I2V5J5|A0A7I2V5J5_HUMAN" 4 1062.5477 0.001 6264 18634 2 1062.546718 532.2811 Peptidyl-prolyl cis-trans isomerase A OS=Homo sapiens OX=9606 GN=PPIA PE=1 SV=2 4.37 3572.5 - 3.42E+06 - - - -0.9355 - 1.774 0.404 - 258.4 1 2 0 -0.001 9 0 0 0 0.00E+00 4.37E+07 - - - 3.683 0.9465 221125_WJC_METTL3_EV_vs_WT_F01.18638.18638.2 0.247 18-Jun K.LEPAFLSGLR.C "sp|Q9Y4A5|TRRAP_HUMAN,tr|H0Y4W2|H0Y4W2_HUMAN,tr|F2Z2U4|F2Z2U4_HUMAN" 3 1101.6182 0.84 6267 18638 2 1101.616458 551.8164 Transformation\transcription domain-associated protein OS=Homo sapiens OX=9606 GN=TRRAP PE=1 SV=3 6 3572.9 - 1.25E+06 - - - -1.6222 - 1.315 0.047 - 67.1 5 2 0 -0.0018 10 0 0 0 3.48E+07 4.13E+07 - - - -0.1603 0.9999 221125_WJC_METTL3_EV_vs_WT_F01.18646.18646.2 1.99E-06 24-Dec K.DIPVLVATDVAAR.G "sp|Q86XP3|DDX42_HUMAN,tr|A0A0A0MSJ0|A0A0A0MSJ0_HUMAN" 2 1338.7507 1.32 6275 18646 2 1338.750317 670.3826 ATP-dependent RNA helicase DDX42 OS=Homo sapiens OX=9606 GN=DDX42 PE=1 SV=1 4.21 3573.9 - 414021 - - - -0.298 - 2.256 0.483 - 438 1 2 0 -0.0004 13 0 0 0 1.82E+07 1.38E+07 - - - 4.6964 0.9995 221125_WJC_METTL3_EV_vs_WT_F01.18654.18654.3 0.0011 Sep-36 K.IEVIEIMTDR.G "sp|Q32P51|RA1L2_HUMAN,sp|P09651|ROA1_HUMAN,tr|A0A7I2YQX9|A0A7I2YQX9_HUMAN,tr|F8VZ49|F8VZ49_HUMAN,tr|A0A7I2V3R8|A0A7I2V3R8_HUMAN,tr|F8VTQ5|F8VTQ5_HUMAN,tr|F8W6I7|F8W6I7_HUMAN,tr|H0YH80|H0YH80_HUMAN,tr|A0A7I2V2L6|A0A7I2V2L6_HUMAN,tr|A0A7I2V3W0|A0A7I2V3W0_HUMAN,tr|A0A7I2V5U9|A0A7I2V5U9_HUMAN,tr|A0A2R8Y4L2|A0A2R8Y4L2_HUMAN" 12 1217.6326 0.72 6281 18654 3 1217.630983 406.8848 Heterogeneous nuclear ribonucleoprotein A1-like 2 OS=Homo sapiens OX=9606 GN=HNRNPA1L2 PE=2 SV=2 4.14 3574.9 - 542168 - - - -1.3066 - 1.79 0.339 - 135.8 1 2 0 -0.0016 10 0 0 0 6.26E+06 8.65E+06 - - - 4.0194 0.9998 221125_WJC_METTL3_EV_vs_WT_F01.18657.18657.2 0.000143 20-Nov K.TPPPVLIFAEK.K sp|Q9UJV9|DDX41_HUMAN 1 1210.6962 1.17 6283 18657 2 1210.695855 606.3554 Probable ATP-dependent RNA helicase DDX41 OS=Homo sapiens OX=9606 GN=DDX41 PE=1 SV=2 5.66 3575.3 - 9.65E+06 - - - -0.2527 - 1.979 0.466 - 386.5 1 2 0 -0.0003 11 0 0 0 1.84E+08 1.58E+08 - - - 4.3294 0.9967 221125_WJC_METTL3_EV_vs_WT_F01.18659.18659.2 0.0598 14-Jun R.FYTIEILK.V sp|P12273|PIP_HUMAN 1 1025.5797 53.78 6284 18659 2 1025.579155 513.7971 Prolactin-inducible protein OS=Homo sapiens OX=9606 GN=PIP PE=1 SV=1 6 3575.5 - 5.35E+06 - - - -0.5646 - 1.122 0.294 - 72.9 2 2 0 -0.0006 8 0 0 0 7.66E+08 1.42E+07 - - - 1.425 0.9999 221125_WJC_METTL3_EV_vs_WT_F01.18660.18660.2 9.32E-07 13/18 R.LMALLGQALK[136.11].W sp|Q2TAY7|SMU1_HUMAN 1 1064.6507 0.92 6285 18660 2 1064.6501 533.3326 WD40 repeat-containing protein SMU1 OS=Homo sapiens OX=9606 GN=SMU1 PE=1 SV=2 8.75 3575.5 - 3.75E+06 - - - -0.5983 - 2.461 0.496 - 615.2 1 2 0 -0.0006 10 0 0 0 5.37E+07 5.86E+07 - - - 5.218 0.9998 221125_WJC_METTL3_EV_vs_WT_F01.18661.18661.3 0.00579 Aug-36 R.FEELNADLFR[166.11].G "sp|P54652|HSP72_HUMAN,sp|P11142|HSP7C_HUMAN,tr|E9PNE6|E9PNE6_HUMAN,tr|A8K7Q2|A8K7Q2_HUMAN,tr|E9PKE3|E9PKE3_HUMAN,tr|E9PN89|E9PN89_HUMAN" 6 1262.6171 0.2 6286 18661 3 1262.615556 421.8796 Heat shock-related 70 kDa protein 2 OS=Homo sapiens OX=9606 GN=HSPA2 PE=1 SV=1 4.14 3575.6 - 1.30E+06 - - - -1.2007 - 1.879 0.37 - 139.8 1 2 0 -0.0015 10 0 0 0 2.76E+06 1.38E+07 - - - 4.5067 0.8649 221125_WJC_METTL3_EV_vs_WT_F01.18662.18662.2 5.4 12-Jun R.TWLQSPV.- sp|Q9BST9|RTKN_HUMAN 1 829.4334 - 6287 18662 2 829.432103 415.724 Rhotekin OS=Homo sapiens OX=9606 GN=RTKN PE=1 SV=2 5.19 3575.8 - 728786 - - - -1.5685 - 0.918 0.057 - 113.8 1 2 0 -0.0013 7 0 0 0 - - - - - -0.8095 0.8265 221125_WJC_METTL3_EV_vs_WT_F01.18663.18663.2 3.83 16-Jul K.VQTFPFLGR[166.11].V "sp|P28340|DPOD1_HUMAN,tr|M0QZR8|M0QZR8_HUMAN,tr|A0A2R8Y7K6|A0A2R8Y7K6_HUMAN,tr|A0A2R8Y705|A0A2R8Y705_HUMAN,tr|M0R2B7|M0R2B7_HUMAN,tr|A0A087WYJ2|A0A087WYJ2_HUMAN" 6 1073.5897 0.4 6288 18663 2 1073.585969 537.8021 DNA polymerase delta catalytic subunit OS=Homo sapiens OX=9606 GN=POLD1 PE=1 SV=2 9.72 3575.9 - 685534 - - - -3.5079 - 1.206 0.057 - 104.7 2 2 0 -0.0038 9 0 0 0 3.37E+06 8.32E+06 - - - -0.1318 0.9999 221125_WJC_METTL3_EV_vs_WT_F01.18664.18664.2 2.01E-05 26-Dec R.VDYLVTEEEINLTR.G "sp|P57105|SYJ2B_HUMAN,tr|A0A087X1F5|A0A087X1F5_HUMAN,tr|A0A087WYV9|A0A087WYV9_HUMAN,tr|A0A087WTA2|A0A087WTA2_HUMAN" 4 1692.857 1.86 6289 18664 2 1692.856563 847.4358 Synaptojanin-2-binding protein OS=Homo sapiens OX=9606 GN=SYNJ2BP PE=1 SV=2 4 3576 - 624378 - - - -0.2765 - 2.732 0.542 - 419.7 1 2 0 -0.0005 14 0 0 0 7.02E+06 3.78E+06 - - - 5.5661 0.9999 221125_WJC_METTL3_EV_vs_WT_F01.18666.18666.2 0.0167 14/26 R.VDYLVTEEEINLTR[166.11].G "sp|P57105|SYJ2B_HUMAN,tr|A0A087X1F5|A0A087X1F5_HUMAN,tr|A0A087WYV9|A0A087WYV9_HUMAN,tr|A0A087WTA2|A0A087WTA2_HUMAN" 4 1702.8653 1.86 6291 18666 2 1702.864898 852.4399 Synaptojanin-2-binding protein OS=Homo sapiens OX=9606 GN=SYNJ2BP PE=1 SV=2 4 3576.3 - 479972 - - - -0.2367 - 2.574 0.526 - 554.8 1 2 0 -0.0004 14 0 0 0 7.02E+06 3.78E+06 - - - 5.2985 0.9996 221125_WJC_METTL3_EV_vs_WT_F01.18667.18667.2 0.0407 16-Sep R.LVLELESLR[166.11].R sp|O95613|PCNT_HUMAN 1 1080.6418 1.27 6292 18667 2 1080.640402 541.3282 Pericentrin OS=Homo sapiens OX=9606 GN=PCNT PE=1 SV=4 4.53 3576.4 - 445468 - - - -1.3214 - 2.093 0.321 - 220.6 1 2 0 -0.0014 9 0 0 0 4.61E+06 3.61E+06 - - - 3.5483 0.9997 221125_WJC_METTL3_EV_vs_WT_F01.18670.18670.2 0.00623 18-Nov K.IEVIEIMTDR.G "sp|Q32P51|RA1L2_HUMAN,sp|P09651|ROA1_HUMAN,tr|A0A7I2YQX9|A0A7I2YQX9_HUMAN,tr|F8VZ49|F8VZ49_HUMAN,tr|A0A7I2V3R8|A0A7I2V3R8_HUMAN,tr|F8VTQ5|F8VTQ5_HUMAN,tr|F8W6I7|F8W6I7_HUMAN,tr|H0YH80|H0YH80_HUMAN,tr|A0A7I2V2L6|A0A7I2V2L6_HUMAN,tr|A0A7I2V3W0|A0A7I2V3W0_HUMAN,tr|A0A7I2V5U9|A0A7I2V5U9_HUMAN,tr|A0A2R8Y4L2|A0A2R8Y4L2_HUMAN" 12 1217.6326 1.18 6293 18670 2 1217.631061 609.8236 Heterogeneous nuclear ribonucleoprotein A1-like 2 OS=Homo sapiens OX=9606 GN=HNRNPA1L2 PE=2 SV=2 4.14 3576.8 - 5.70E+07 - - - -1.2426 - 2.26 0.367 - 467.3 1 2 0 -0.0015 10 0 0 0 8.54E+08 7.21E+08 - - - 4.0271 0.9998 221125_WJC_METTL3_EV_vs_WT_F01.18671.18671.2 0.00052 18-Aug K.GIFLGDDEWR.E "sp|Q8TB72|PUM2_HUMAN,tr|C9JW01|C9JW01_HUMAN" 2 1206.5669 1.49 6294 18671 2 1206.566733 604.2907 Pumilio homolog 2 OS=Homo sapiens OX=9606 GN=PUM2 PE=1 SV=2 4.03 3576.8 - 9.48E+06 - - - -0.1691 - 1.87 0.48 - 170.9 1 2 0 -0.0002 10 0 0 0 1.14E+08 7.65E+07 - - - 4.3334 0.9991 221125_WJC_METTL3_EV_vs_WT_F01.18672.18672.2 0.205 16-Oct K.LTQILSYLR[166.11].Q sp|Q13123|RED_HUMAN 1 1115.6578 1.33 6295 18672 2 1115.660679 558.8362 Protein Red OS=Homo sapiens OX=9606 GN=IK PE=1 SV=3 8.75 3576.9 - 6.80E+06 - - - 2.5671 - 2.103 0.337 - 439.3 1 2 0 0.0029 9 0 0 0 9.26E+07 6.97E+07 - - - 3.6798 0.9998 221125_WJC_METTL3_EV_vs_WT_F01.18675.18675.2 1.45E-06 13/20 R.YLLEQDFPGMR.L "sp|Q9H223|EHD4_HUMAN,sp|Q9NZN3|EHD3_HUMAN" 2 1367.6544 1.43 6298 18675 2 1367.653504 684.8345 EH domain-containing protein 4 OS=Homo sapiens OX=9606 GN=EHD4 PE=1 SV=1 4.37 3577.1 - 1.21E+06 - - - -0.6347 - 2.071 0.408 - 636.9 1 2 0 -0.0009 11 0 0 0 1.52E+07 1.07E+07 - - - 4.0237 0.9965 221125_WJC_METTL3_EV_vs_WT_F01.18677.18677.2 0.000252 20-Sep R.YLLEQDFPGMR[166.11].L "sp|Q9H223|EHD4_HUMAN,sp|Q9NZN3|EHD3_HUMAN" 2 1377.6626 1.43 6300 18677 2 1377.658617 689.8386 EH domain-containing protein 4 OS=Homo sapiens OX=9606 GN=EHD4 PE=1 SV=1 4.37 3577.4 - 950384 - - - -2.9216 - 1.852 0.247 - 293.6 1 2 0 -0.004 11 0 0 0 1.52E+07 1.07E+07 - - - 2.5312 0.9999 221125_WJC_METTL3_EV_vs_WT_F01.18679.18679.2 0.000368 14/24 R.ILLAEVPTMAVEK[136.11].V "sp|O15160|RPAC1_HUMAN,tr|D6RDJ3|D6RDJ3_HUMAN,tr|A0A2R8YEZ4|A0A2R8YEZ4_HUMAN,tr|H0Y723|H0Y723_HUMAN,tr|E7EQB9|E7EQB9_HUMAN,tr|A0A2R8Y5D3|A0A2R8Y5D3_HUMAN,tr|A0A2R8YEY5|A0A2R8YEY5_HUMAN,tr|A0A2R8Y8D6|A0A2R8Y8D6_HUMAN" 8 1420.8091 0.21 6302 18679 2 1420.808024 711.4118 DNA-directed RNA polymerases I and III subunit RPAC1 OS=Homo sapiens OX=9606 GN=POLR1C PE=1 SV=1 4.53 3577.6 - 768465 - - - -0.7496 - 2.466 0.47 - 567.6 1 2 0 -0.0011 13 0 0 0 2.23E+07 1.08E+08 - - - 4.8286 0.9218 221125_WJC_METTL3_EV_vs_WT_F01.18680.18680.2 0.332 14-Aug L.LALIDALR.D "sp|Q9NYL9|TMOD3_HUMAN,tr|H0YKU1|H0YKU1_HUMAN,tr|H0YNJ8|H0YNJ8_HUMAN" 3 883.5491 0.87 6303 18680 2 883.547716 442.7818 Tropomodulin-3 OS=Homo sapiens OX=9606 GN=TMOD3 PE=1 SV=1 5.84 3577.8 - 674149 - - - -1.5687 - 1.737 0.242 - 233.2 1 1 0 -0.0014 8 0 0 0 6.29E+06 7.24E+06 - - - 2.4933 0.9992 221125_WJC_METTL3_EV_vs_WT_F01.18684.18684.2 0.0207 14-Aug R.DFVNYLVR[166.11].L sp|Q08211|DHX9_HUMAN 1 1034.5425 0.97 6306 18684 2 1034.540776 518.2785 ATP-dependent RNA helicase A OS=Homo sapiens OX=9606 GN=DHX9 PE=1 SV=4 5.84 3578.2 - 2.26E+07 - - - -1.6191 - 1.71 0.333 - 270.2 1 2 0 -0.0017 8 0 0 0 2.91E+08 2.99E+08 - - - 3.1181 0.9998 221125_WJC_METTL3_EV_vs_WT_F01.18685.18685.2 0.000182 16-Nov K.LTQILSYLR.Q sp|Q13123|RED_HUMAN 1 1105.6495 1.34 6307 18685 2 1105.648575 553.832 Protein Red OS=Homo sapiens OX=9606 GN=IK PE=1 SV=3 8.75 3578.3 - 8.48E+06 - - - -0.8773 - 2.245 0.378 - 623.2 1 2 0 -0.001 9 0 0 0 9.45E+07 7.04E+07 - - - 4.1722 0.9997 221125_WJC_METTL3_EV_vs_WT_F01.18687.18687.2 0.000186 18-Dec R.LMALLGQALK.W sp|Q2TAY7|SMU1_HUMAN 1 1056.6365 0.92 6309 18687 2 1056.635016 529.3255 WD40 repeat-containing protein SMU1 OS=Homo sapiens OX=9606 GN=SMU1 PE=1 SV=2 8.75 3578.4 - 6.10E+06 - - - -1.4395 - 2.31 0.347 - 529.8 1 2 0 -0.0015 10 0 0 0 5.37E+07 5.86E+07 - - - 3.9405 0.9995 221125_WJC_METTL3_EV_vs_WT_F01.18688.18688.2 0.0122 16-Sep K.ASSLISLLK.Q "sp|P78344|IF4G2_HUMAN,tr|E9PKF8|E9PKF8_HUMAN,tr|H0Y3P2|H0Y3P2_HUMAN,tr|D3DQV9|D3DQV9_HUMAN" 4 930.575 2.39 6310 18688 2 930.573589 466.2948 Eukaryotic translation initiation factor 4 gamma 2 OS=Homo sapiens OX=9606 GN=EIF4G2 PE=1 SV=1 8.8 3578.4 - 4.92E+06 - - - -1.498 - 1.77 0.387 - 259 1 2 0 -0.0014 9 0 0 0 5.11E+07 2.13E+07 - - - 3.5508 0.9998 221125_WJC_METTL3_EV_vs_WT_F01.18690.18690.2 6.85E-05 16-Nov K.GLDFALLQK.V "sp|Q13123|RED_HUMAN,tr|D6REL4|D6REL4_HUMAN,tr|E7EQZ7|E7EQZ7_HUMAN" 3 1003.5702 0.95 6312 18690 2 1003.56929 502.7924 Protein Red OS=Homo sapiens OX=9606 GN=IK PE=1 SV=3 5.84 3578.6 - 1.99E+06 - - - -0.9386 - 1.959 0.453 - 277.5 1 2 0 -0.0009 9 0 0 0 9.27E+07 9.73E+07 - - - 4.332 0.9841 221125_WJC_METTL3_EV_vs_WT_F01.18691.18691.2 0.0213 18-Oct R.TLDLPIYVTR.V "sp|P53621|COPA_HUMAN,tr|A0A3B3ISC6|A0A3B3ISC6_HUMAN,tr|A0A3B3IS84|A0A3B3IS84_HUMAN,tr|A0A3B3IU89|A0A3B3IU89_HUMAN,tr|A0A3B3IT15|A0A3B3IT15_HUMAN" 5 1189.6707 0.15 6313 18691 2 1189.663288 595.8426 Coatomer subunit alpha OS=Homo sapiens OX=9606 GN=COPA PE=1 SV=2 5.5 3578.6 - 1.50E+06 - - - -6.2084 - 1.779 0.369 - 359.4 1 2 0 -0.0074 10 0 0 0 1.45E+07 9.60E+07 - - - 3.372 0.9963 221125_WJC_METTL3_EV_vs_WT_F01.18694.18694.2 1.17E-05 16-Oct K.MC[160.03]LFAGFQR[166.11].K "sp|Q00839|HNRPU_HUMAN,tr|A0A1W2PQL0|A0A1W2PQL0_HUMAN,tr|A0A1W2PPL4|A0A1W2PPL4_HUMAN,tr|A0A1W2PQ74|A0A1W2PQ74_HUMAN,tr|Q5RI18|Q5RI18_HUMAN,tr|A0A1W2PP35|A0A1W2PP35_HUMAN,tr|A0A1W2PPS1|A0A1W2PPS1_HUMAN,tr|A0A1W2PRZ7|A0A1W2PRZ7_HUMAN,tr|A0A1W2PPH7|A0A1W2PPH7_HUMAN,tr|A0A1W2PQD4|A0A1W2PQD4_HUMAN,tr|A0A1W2PP34|A0A1W2PP34_HUMAN,tr|A0A1X7SBS1|A0A1X7SBS1_HUMAN" 12 1138.5291 0.92 6316 18694 2 1138.524077 570.2718 Heterogeneous nuclear ribonucleoprotein U OS=Homo sapiens OX=9606 GN=HNRNPU PE=1 SV=6 8 3579 - 994646 - - - -4.4347 - 2.014 0.346 - 313.6 1 2 0 -0.005 9 0 0 0 2.58E+08 2.82E+08 - - - 3.6205 0.9996 221125_WJC_METTL3_EV_vs_WT_F01.18695.18695.2 0.312 14-Sep R.VLLLPLER[166.11].D sp|O95071|UBR5_HUMAN 1 961.62 0.55 6317 18695 2 961.618946 481.8173 E3 ubiquitin-protein ligase UBR5 OS=Homo sapiens OX=9606 GN=UBR5 PE=1 SV=2 5.97 3579.1 - 927761 - - - -1.068 - 2.002 0.31 - 344.7 1 2 0 -0.001 8 0 0 0 1.16E+07 2.12E+07 - - - 3.4239 0.9991 221125_WJC_METTL3_EV_vs_WT_F01.18697.18697.2 0.0212 15/24 K.DIPVLVATDVAAR[166.11].G "sp|Q86XP3|DDX42_HUMAN,tr|A0A0A0MSJ0|A0A0A0MSJ0_HUMAN" 2 1348.759 1.35 6319 18697 2 1348.755052 675.3868 ATP-dependent RNA helicase DDX42 OS=Homo sapiens OX=9606 GN=DDX42 PE=1 SV=1 4.21 3579.4 - 769446 - - - -2.9168 - 2.514 0.353 - 505.7 1 2 0 -0.0039 13 0 0 0 1.77E+07 1.31E+07 - - - 4.013 0.9999 221125_WJC_METTL3_EV_vs_WT_F01.18699.18699.2 0.0205 14/22 K.IIENELEGFGIR[166.11].L sp|Q9Y295|DRG1_HUMAN 1 1398.7383 0.47 6321 18699 2 1398.736995 700.3764 Developmentally-regulated GTP-binding protein 1 OS=Homo sapiens OX=9606 GN=DRG1 PE=1 SV=1 4.25 3579.6 - 317247 - - - -0.8972 - 2.715 0.478 - 596.1 1 2 0 -0.0013 12 0 0 0 1.69E+07 3.60E+07 - - - 5.1991 0.9998 221125_WJC_METTL3_EV_vs_WT_F01.18705.18705.2 0.000105 16-Aug K.GLDFALLQK[136.11].V "sp|Q13123|RED_HUMAN,tr|D6REL4|D6REL4_HUMAN,tr|E7EQZ7|E7EQZ7_HUMAN" 3 1011.5844 0.95 6325 18705 2 1011.584559 506.7995 Protein Red OS=Homo sapiens OX=9606 GN=IK PE=1 SV=3 5.84 3580.2 - 6.01E+06 - - - 0.1255 - 1.757 0.504 - 176.6 1 2 0 0.0001 9 0 0 0 9.27E+07 9.73E+07 - - - 4.3941 0.9996 221125_WJC_METTL3_EV_vs_WT_F01.18706.18706.2 0.00081 20-Nov R.LMMDPLTGLNR[166.11].G "sp|O60506|HNRPQ_HUMAN,tr|A0A7I2YQN2|A0A7I2YQN2_HUMAN,tr|A0A7I2V5Q6|A0A7I2V5Q6_HUMAN,tr|A0A7I2V4Z0|A0A7I2V4Z0_HUMAN,tr|B7Z645|B7Z645_HUMAN,tr|A0A7I2V2F2|A0A7I2V2F2_HUMAN,tr|A0A7I2V346|A0A7I2V346_HUMAN,tr|A0A7I2V309|A0A7I2V309_HUMAN" 8 1269.6449 0.76 6326 18706 2 1269.641781 635.8297 Heterogeneous nuclear ribonucleoprotein Q OS=Homo sapiens OX=9606 GN=SYNCRIP PE=1 SV=2 5.84 3580.3 - 3.28E+06 - - - -2.444 - 2.105 0.505 - 277.4 1 2 0 -0.0031 11 0 0 0 4.28E+07 5.63E+07 - - - 4.7835 0.9998 221125_WJC_METTL3_EV_vs_WT_F01.18707.18707.2 0.000102 16-Sep K.MC[160.03]LFAGFQR.K "sp|Q00839|HNRPU_HUMAN,tr|A0A1W2PQL0|A0A1W2PQL0_HUMAN,tr|A0A1W2PPL4|A0A1W2PPL4_HUMAN,tr|A0A1W2PQ74|A0A1W2PQ74_HUMAN,tr|Q5RI18|Q5RI18_HUMAN,tr|A0A1W2PP35|A0A1W2PP35_HUMAN,tr|A0A1W2PPS1|A0A1W2PPS1_HUMAN,tr|A0A1W2PRZ7|A0A1W2PRZ7_HUMAN,tr|A0A1W2PPH7|A0A1W2PPH7_HUMAN,tr|A0A1W2PQD4|A0A1W2PQD4_HUMAN,tr|A0A1W2PP34|A0A1W2PP34_HUMAN,tr|A0A1X7SBS1|A0A1X7SBS1_HUMAN" 12 1128.5209 0.92 6327 18707 2 1128.520797 565.2677 Heterogeneous nuclear ribonucleoprotein U OS=Homo sapiens OX=9606 GN=HNRNPU PE=1 SV=6 8 3580.4 - 2.74E+06 - - - -0.0523 - 1.902 0.394 - 463.3 1 2 0 -0.0001 9 0 0 0 2.58E+08 2.82E+08 - - - 3.811 0.9987 221125_WJC_METTL3_EV_vs_WT_F01.18709.18709.2 1.36E-05 20-Nov R.FLMSLVNQVPK[136.11].L "sp|O00303|EIF3F_HUMAN,tr|H0YDT6|H0YDT6_HUMAN" 2 1282.7199 0.9 6329 18709 2 1282.722239 642.3672 Eukaryotic translation initiation factor 3 subunit F OS=Homo sapiens OX=9606 GN=EIF3F PE=1 SV=1 8.75 3580.6 - 927958 - - - 1.8391 - 1.847 0.282 - 334.9 1 2 0 0.0024 11 0 0 0 4.33E+07 4.79E+07 - - - 2.7829 0.9907 221125_WJC_METTL3_EV_vs_WT_F01.18710.18710.2 1.71 14-Sep R.VLLLPLER.D sp|O95071|UBR5_HUMAN 1 951.6117 0.55 6330 18710 2 951.609873 476.8131 E3 ubiquitin-protein ligase UBR5 OS=Homo sapiens OX=9606 GN=UBR5 PE=1 SV=2 5.97 3580.7 - 1.16E+06 - - - -1.9231 - 1.578 0.102 - 236.2 1 2 0 -0.0018 8 0 0 0 1.16E+07 2.12E+07 - - - 1.1695 0.9988 221125_WJC_METTL3_EV_vs_WT_F01.18716.18716.2 0.156 16-Jul K.SGILPILVK[136.11].C sp|O00505|IMA4_HUMAN 1 946.6307 0.71 6334 18716 2 946.629717 474.3226 Importin subunit alpha-4 OS=Homo sapiens OX=9606 GN=KPNA3 PE=1 SV=2 8.47 3581.5 - 2.41E+06 - - - -0.9898 - 1.524 0.284 - 106.7 1 2 0 -0.0009 9 0 0 0 2.01E+07 2.81E+07 - - - 2.3573 0.8532 221125_WJC_METTL3_EV_vs_WT_F01.18717.18717.2 0.534 22-Jul K.GGEAEKQTAEFK[136.11].L sp|Q6NT04|TIGD7_HUMAN 1 1301.6343 - 6335 18717 2 1301.630351 651.8244 Tigger transposable element-derived protein 7 OS=Homo sapiens OX=9606 GN=TIGD7 PE=1 SV=1 4.79 3581.6 - 4.09E+06 - - - -3.03 - 1.465 0.183 - 155.8 1 2 1 -0.0039 12 0 0 0 - - - - - 1.3961 0.9998 221125_WJC_METTL3_EV_vs_WT_F01.18718.18718.2 8.62E-06 20-Oct R.FLMSLVNQVPK.L "sp|O00303|EIF3F_HUMAN,tr|H0YDT6|H0YDT6_HUMAN" 2 1274.7057 0.9 6336 18718 2 1274.70525 638.3601 Eukaryotic translation initiation factor 3 subunit F OS=Homo sapiens OX=9606 GN=EIF3F PE=1 SV=1 8.75 3581.6 - 1.69E+06 - - - -0.3373 - 1.916 0.488 - 298 1 2 0 -0.0004 11 0 0 0 4.29E+07 4.74E+07 - - - 4.4043 0.9997 221125_WJC_METTL3_EV_vs_WT_F01.18720.18720.2 4.14E-06 18-Nov K.TIC[160.03]AEFAILR.M "sp|O75643|U520_HUMAN,tr|A0A494C1A5|A0A494C1A5_HUMAN" 2 1192.6274 0.51 6338 18720 2 1192.628573 597.321 U5 small nuclear ribonucleoprotein 200 kDa helicase OS=Homo sapiens OX=9606 GN=SNRNP200 PE=1 SV=2 5.66 3581.8 - 956928 - - - 0.9592 - 1.922 0.415 - 358.2 1 2 0 0.0011 10 0 0 0 1.27E+07 2.49E+07 - - - 3.9296 0.9905 221125_WJC_METTL3_EV_vs_WT_F01.18722.18722.2 0.129 12-Jun R.GLLEYFK.A "sp|Q6DD88|ATLA3_HUMAN,tr|F5H6I7|F5H6I7_HUMAN" 2 868.4695 1.32 6340 18722 2 868.469829 435.242 Atlastin-3 OS=Homo sapiens OX=9606 GN=ATL3 PE=1 SV=1 6 3582.1 - 744667 - - - 0.4306 - 1.199 0.147 - 107 1 2 0 0.0004 7 0 0 0 1.09E+07 8.23E+06 - - - 0.7017 0.9334 221125_WJC_METTL3_EV_vs_WT_F01.18723.18723.2 0.457 Jun-34 R.GSAAALC[160.03]NNLSVLQLPAR.N sp|Q9H977|WDR54_HUMAN 1 1853.9782 999 6341 18723 2 1853.98331 927.9964 WD repeat-containing protein 54 OS=Homo sapiens OX=9606 GN=WDR54 PE=1 SV=1 8.25 3582.2 - 633718 - - - 2.7746 - 1.398 0.068 - 62.1 2 2 0 0.0051 18 0 0 0 7.67E+06 0.00E+00 - - - 0.2309 0.9999 221125_WJC_METTL3_EV_vs_WT_F01.18729.18729.2 1.50E-05 20-Nov R.LLDMDGIIVEK[136.11].Q sp|Q14152|EIF3A_HUMAN 1 1252.6828 1.16 6345 18729 2 1252.681972 627.3487 Eukaryotic translation initiation factor 3 subunit A OS=Homo sapiens OX=9606 GN=EIF3A PE=1 SV=1 4.03 3582.9 - 4.95E+06 - - - -0.6809 - 2.037 0.502 - 338.6 1 2 0 -0.0009 11 0 0 0 5.91E+07 5.11E+07 - - - 4.6732 0.9964 221125_WJC_METTL3_EV_vs_WT_F01.18731.18731.2 5.32E-05 16-Oct K.VFDAIMNFK[136.11].K sp|P13639|EF2_HUMAN 1 1091.5565 0.45 6347 18731 2 1091.552243 546.7855 Elongation factor 2 OS=Homo sapiens OX=9606 GN=EEF2 PE=1 SV=4 5.81 3583.1 - 1.32E+06 - - - -3.9027 - 1.77 0.341 - 254.6 1 2 0 -0.0043 9 0 0 0 3.77E+07 8.33E+07 - - - 3.2102 0.9818 221125_WJC_METTL3_EV_vs_WT_F01.18732.18732.2 0.362 12-Apr R.GLLEYFK[136.11].A "sp|Q6DD88|ATLA3_HUMAN,tr|F5H6I7|F5H6I7_HUMAN" 2 876.4837 1.86 6348 18732 2 876.483299 439.2491 Atlastin-3 OS=Homo sapiens OX=9606 GN=ATL3 PE=1 SV=1 6 3583.2 - 831153 - - - -0.4062 - 1.081 0.185 - 41.8 9 2 0 -0.0004 7 0 0 0 1.60E+07 8.64E+06 - - - 0.2278 0.9952 221125_WJC_METTL3_EV_vs_WT_F01.18737.18737.2 0.0949 26-Jun R.FGFPEGSVELYAEK.V "sp|P23396|RS3_HUMAN,tr|F2Z2S8|F2Z2S8_HUMAN,tr|H0YCJ7|H0YCJ7_HUMAN,tr|E9PPU1|E9PPU1_HUMAN,tr|H0YF32|H0YF32_HUMAN" 5 1571.7508 0.14 6353 18737 2 1571.750468 786.8827 40S ribosomal protein S3 OS=Homo sapiens OX=9606 GN=RPS3 PE=1 SV=2 4.25 3583.9 - 259758 - - - -0.1953 - 1.175 0.256 - 34.5 3 2 0 -0.0003 14 0 0 0 4.88E+06 3.56E+07 - - - 1.1233 0.9953 221125_WJC_METTL3_EV_vs_WT_F01.18739.18739.2 0.0518 14-Sep R.IPLNDLFR[166.11].C sp|P13473|LAMP2_HUMAN 1 996.5632 0.47 6354 18739 2 996.567473 499.2889 Lysosome-associated membrane glycoprotein 2 OS=Homo sapiens OX=9606 GN=LAMP2 PE=1 SV=2 5.84 3584.1 - 2.52E+06 - - - 4.3018 - 1.782 0.336 - 313.6 1 2 0 0.0043 8 0 0 0 4.83E+07 1.02E+08 - - - 3.2638 0.9999 221125_WJC_METTL3_EV_vs_WT_F01.18742.18742.2 0.000139 20-Dec R.LAVDLSEVVIK.W "sp|Q9Y4A5|TRRAP_HUMAN,tr|H0Y4W2|H0Y4W2_HUMAN,tr|F2Z2U4|F2Z2U4_HUMAN" 3 1184.7016 1.44 6356 18742 2 1184.700906 593.3581 Transformation\transcription domain-associated protein OS=Homo sapiens OX=9606 GN=TRRAP PE=1 SV=3 4.37 3584.4 - 1.35E+06 - - - -0.6196 - 2.562 0.461 - 442.8 1 2 0 -0.0007 11 0 0 0 1.84E+07 1.28E+07 - - - 4.9908 0.9921 221125_WJC_METTL3_EV_vs_WT_F01.18743.18743.2 0.438 14-Jul R.IPLNDLFR.C sp|P13473|LAMP2_HUMAN 1 986.5549 0.47 6357 18743 2 986.558315 494.2847 Lysosome-associated membrane glycoprotein 2 OS=Homo sapiens OX=9606 GN=LAMP2 PE=1 SV=2 5.84 3584.4 - 1.33E+06 - - - 3.4453 - 1.614 0.229 - 128.7 1 2 0 0.0034 8 0 0 0 4.83E+07 1.02E+08 - - - 2.1751 0.995 221125_WJC_METTL3_EV_vs_WT_F01.18745.18745.2 6.91E-05 18-Sep K.TIC[160.03]AEFAILR[166.11].M "sp|O75643|U520_HUMAN,tr|A0A494C1A5|A0A494C1A5_HUMAN" 2 1202.6357 0.38 6359 18745 2 1202.631033 602.3251 U5 small nuclear ribonucleoprotein 200 kDa helicase OS=Homo sapiens OX=9606 GN=SNRNP200 PE=1 SV=2 5.66 3584.6 - 711621 - - - -3.8798 - 1.583 0.343 - 212.9 1 2 0 -0.0047 10 0 0 0 1.28E+07 3.40E+07 - - - 2.855 0.9297 221125_WJC_METTL3_EV_vs_WT_F01.18746.18746.2 0.0589 16-Jul V.ALLPFVDER.R sp|Q9H0D6|XRN2_HUMAN 1 1058.576 1.95 6360 18746 2 1058.576251 530.2953 5'-3' exoribonuclease 2 OS=Homo sapiens OX=9606 GN=XRN2 PE=1 SV=1 4.37 3584.8 - 699327 - - - 0.1937 - 1.54 0.257 - 138.1 1 1 0 0.0002 9 0 0 0 5.52E+06 2.83E+06 - - - 2.1883 0.9965 221125_WJC_METTL3_EV_vs_WT_F01.18747.18747.2 0.23 12-Jul R.IQLLVFK.H "sp|Q9Y262|EIF3L_HUMAN,tr|B0QY89|B0QY89_HUMAN,tr|B0QY90|B0QY90_HUMAN" 3 859.5531 0.95 6361 18747 2 859.552926 430.7838 Eukaryotic translation initiation factor 3 subunit L OS=Homo sapiens OX=9606 GN=EIF3L PE=1 SV=1 8.75 3584.9 - 610595 - - - -0.2315 - 1.654 0.098 - 149.7 1 2 0 -0.0002 7 0 0 0 2.51E+07 2.64E+07 - - - 1.3592 0.9998 221125_WJC_METTL3_EV_vs_WT_F01.18748.18748.2 2.50E-05 20-Nov R.LEPLVNDLTLR[166.11].L sp|Q70UQ0|IKIP_HUMAN 1 1291.7375 1.07 6362 18748 2 1291.738639 646.876 Inhibitor of nuclear factor kappa-B kinase-interacting protein OS=Homo sapiens OX=9606 GN=IKBIP PE=1 SV=1 4.37 3585 - 556574 - - - 0.8647 - 2.107 0.49 - 508.3 1 2 0 0.0011 11 0 0 0 1.13E+07 1.06E+07 - - - 4.6759 0.9863 221125_WJC_METTL3_EV_vs_WT_F01.18752.18752.2 0.000184 18-Sep R.LYDVVAVFPK.T "sp|P78346|RPP30_HUMAN,tr|Q5VU11|Q5VU11_HUMAN,tr|Q5VU10|Q5VU10_HUMAN" 3 1149.6434 1.22 6366 18752 2 1149.65046 575.829 Ribonuclease P protein subunit p30 OS=Homo sapiens OX=9606 GN=RPP30 PE=1 SV=1 5.83 3585.6 - 286219 - - - 6.1436 - 1.715 0.398 - 184.1 1 2 0 0.0071 10 0 0 0 6.45E+06 5.31E+06 - - - 3.4841 0.9999 221125_WJC_METTL3_EV_vs_WT_F01.18755.18755.2 0.000149 15/24 R.ILLAEVPTMAVEK.V "sp|O15160|RPAC1_HUMAN,tr|D6RDJ3|D6RDJ3_HUMAN,tr|A0A2R8YEZ4|A0A2R8YEZ4_HUMAN,tr|H0Y723|H0Y723_HUMAN,tr|E7EQB9|E7EQB9_HUMAN,tr|A0A2R8Y5D3|A0A2R8Y5D3_HUMAN,tr|A0A2R8YEY5|A0A2R8YEY5_HUMAN,tr|A0A2R8Y8D6|A0A2R8Y8D6_HUMAN" 8 1412.7949 0.21 6368 18755 2 1412.795525 707.4047 DNA-directed RNA polymerases I and III subunit RPAC1 OS=Homo sapiens OX=9606 GN=POLR1C PE=1 SV=1 4.53 3585.9 - 1.33E+06 - - - 0.4502 - 2.568 0.455 - 709.2 1 2 0 0.0006 13 0 0 0 2.23E+07 1.08E+08 - - - 4.822 1 221125_WJC_METTL3_EV_vs_WT_F01.18757.18757.2 8.86E-09 14/20 M.PPYTVVYFPVR.G "sp|P09211|GSTP1_HUMAN,tr|A0A2R8Y5E5|A0A2R8Y5E5_HUMAN,tr|A8MX94|A8MX94_HUMAN" 3 1336.718 2.16 6369 18757 2 1336.71837 669.3663 Glutathione S-transferase P OS=Homo sapiens OX=9606 GN=GSTP1 PE=1 SV=2 9 3586.1 - 8.05E+06 - - - 0.3075 - 2.782 0.569 - 954.5 1 2 0 0.0004 11 0 0 0 8.41E+07 3.90E+07 - - - 6.0114 1 221125_WJC_METTL3_EV_vs_WT_F01.18758.18758.2 5.52E-07 14/20 M.PPYTVVYFPVR[166.11].G "sp|P09211|GSTP1_HUMAN,tr|A0A2R8Y5E5|A0A2R8Y5E5_HUMAN,tr|A8MX94|A8MX94_HUMAN" 3 1346.7262 2.16 6370 18758 2 1346.727005 674.3704 Glutathione S-transferase P OS=Homo sapiens OX=9606 GN=GSTP1 PE=1 SV=2 9 3586.2 - 4.01E+06 - - - 0.5762 - 2.829 0.524 - 826.5 1 2 0 0.0008 11 0 0 0 8.41E+07 3.90E+07 - - - 5.7243 0.9963 221125_WJC_METTL3_EV_vs_WT_F01.18759.18759.2 0.0253 12-Sep R.IQLLVFK[136.11].H "sp|Q9Y262|EIF3L_HUMAN,tr|B0QY89|B0QY89_HUMAN,tr|B0QY90|B0QY90_HUMAN" 3 867.5673 0.95 6371 18759 2 867.566856 434.7909 Eukaryotic translation initiation factor 3 subunit L OS=Homo sapiens OX=9606 GN=EIF3L PE=1 SV=1 8.75 3586.2 - 2.49E+06 - - - -0.5406 - 1.731 0.077 - 239.7 1 2 0 -0.0005 7 0 0 0 2.51E+07 2.64E+07 - - - 1.3482 0.9999 221125_WJC_METTL3_EV_vs_WT_F01.18760.18760.2 8.72E-06 20-Dec R.LMMDPLTGLNR.G "sp|O60506|HNRPQ_HUMAN,tr|A0A7I2YQN2|A0A7I2YQN2_HUMAN,tr|A0A7I2V5Q6|A0A7I2V5Q6_HUMAN,tr|A0A7I2V4Z0|A0A7I2V4Z0_HUMAN,tr|B7Z645|B7Z645_HUMAN,tr|A0A7I2V2F2|A0A7I2V2F2_HUMAN,tr|A0A7I2V346|A0A7I2V346_HUMAN,tr|A0A7I2V309|A0A7I2V309_HUMAN" 8 1259.6366 0.75 6372 18760 2 1259.636365 630.8256 Heterogeneous nuclear ribonucleoprotein Q OS=Homo sapiens OX=9606 GN=SYNCRIP PE=1 SV=2 5.84 3586.3 - 1.89E+06 - - - -0.1977 - 2.093 0.528 - 400.1 1 2 0 -0.0002 11 0 0 0 4.24E+07 5.63E+07 - - - 4.9388 0.9988 221125_WJC_METTL3_EV_vs_WT_F01.18762.18762.2 0.00963 12-Jun K.DYVDLFR.H sp|P78527|PRKDC_HUMAN 1 926.4498 0.09 6374 18762 2 926.450504 464.2322 DNA-dependent protein kinase catalytic subunit OS=Homo sapiens OX=9606 GN=PRKDC PE=1 SV=3 4.21 3586.5 - 1.04E+06 - - - 0.7793 - 1.323 0.329 - 167.1 1 2 0 0.0007 7 0 0 0 1.11E+07 1.29E+08 - - - 2.3577 1 221125_WJC_METTL3_EV_vs_WT_F01.18763.18763.2 2.47E-08 13/24 R.TPFTTSQLLALER[166.11].K sp|P35548|MSX2_HUMAN 1 1485.8067 1.49 6375 18763 2 1485.808394 743.9106 Homeobox protein MSX-2 OS=Homo sapiens OX=9606 GN=MSX2 PE=1 SV=3 5.66 3586.7 - 803406 - - - 1.1644 - 2.85 0.605 - 703.4 1 2 0 0.0017 13 0 0 0 1.22E+07 8.19E+06 - - - 6.197 0.9998 221125_WJC_METTL3_EV_vs_WT_F01.18764.18764.2 0.00247 14/28 R.AILVDLEPGTMDSVR[166.11].S "sp|Q9BVA1|TBB2B_HUMAN,sp|P07437|TBB5_HUMAN,sp|Q13509|TBB3_HUMAN,sp|Q13885|TBB2A_HUMAN,tr|A0A0B4J269|A0A0B4J269_HUMAN,tr|Q5JP53|Q5JP53_HUMAN,tr|G3V3R4|G3V3R4_HUMAN,tr|G3V5W4|G3V5W4_HUMAN,tr|G3V2R8|G3V2R8_HUMAN,tr|G3V2N6|G3V2N6_HUMAN" 10 1624.837 0.66 6376 18764 2 1624.83645 813.4258 Tubulin beta-2B chain OS=Homo sapiens OX=9606 GN=TUBB2B PE=1 SV=1 4.03 3586.8 - 697583 - - - -0.325 - 2.607 0.37 - 523.6 1 2 0 -0.0005 15 0 0 0 2.31E+07 3.53E+07 - - - 4.1294 0.9997 221125_WJC_METTL3_EV_vs_WT_F01.18766.18766.2 0.0695 16-Sep K.LLIYWASTR.E sp|P06312|KV401_HUMAN 1 1121.6233 22.98 6378 18766 2 1121.622416 561.8189 Immunoglobulin kappa variable 4-1 OS=Homo sapiens OX=9606 GN=IGKV4-1 PE=1 SV=1 8.75 3587 - 472763 - - - -0.8149 - 1.995 0.361 - 248.1 1 2 0 -0.0009 9 0 0 0 2.56E+07 1.12E+06 - - - 3.7051 0.9996 221125_WJC_METTL3_EV_vs_WT_F01.18773.18773.2 0.178 18-Oct K.SVVTSIFGVK.N "sp|P41252|SYIC_HUMAN,tr|A0A804HL54|A0A804HL54_HUMAN,tr|A0A804HJN6|A0A804HJN6_HUMAN,tr|A0A0A0MSX9|A0A0A0MSX9_HUMAN" 4 1035.5964 0.83 6383 18773 2 1035.596597 518.8055 "Isoleucine--tRNA ligase, cytoplasmic OS=Homo sapiens OX=9606 GN=IARS1 PE=1 SV=2" 8.47 3587.8 - 2.50E+06 - - - 0.1448 - 1.895 0.32 - 281.9 1 2 0 0.0001 10 0 0 0 2.61E+07 3.13E+07 - - - 3.1887 0.9998 221125_WJC_METTL3_EV_vs_WT_F01.18774.18774.2 0.0126 18-Oct R.LFDQAFGLPR.L "sp|P04792|HSPB1_HUMAN,tr|A0A6Q8PGY2|A0A6Q8PGY2_HUMAN,tr|A0A6Q8PHJ6|A0A6Q8PHJ6_HUMAN,tr|A0A6Q8PHA6|A0A6Q8PHA6_HUMAN,tr|A0A6Q8PF43|A0A6Q8PF43_HUMAN,tr|A0A6Q8PFK8|A0A6Q8PFK8_HUMAN,tr|A0A6Q8PGK1|A0A6Q8PGK1_HUMAN,tr|A0A6Q8PH65|A0A6Q8PH65_HUMAN,tr|A0A6Q8PFE7|A0A6Q8PFE7_HUMAN" 9 1162.6135 1.53 6384 18774 2 1162.613821 582.314 Heat shock protein beta-1 OS=Homo sapiens OX=9606 GN=HSPB1 PE=1 SV=2 5.84 3587.9 - 2.82E+06 - - - 0.2813 - 2.144 0.42 - 387.7 1 2 0 0.0003 10 0 0 0 7.65E+08 5.01E+08 - - - 4.2719 0.9997 221125_WJC_METTL3_EV_vs_WT_F01.18775.18775.2 0.00321 16-Oct K.FALNSLLQR.Q "sp|P39880|CUX1_HUMAN,tr|A0A2R8Y852|A0A2R8Y852_HUMAN" 2 1060.6029 1.41 6385 18775 2 1060.604529 531.3087 Homeobox protein cut-like 1 OS=Homo sapiens OX=9606 GN=CUX1 PE=1 SV=3 9.75 3588 - 1.52E+06 - - - 1.5086 - 2.089 0.426 - 386.2 1 2 0 0.0016 9 0 0 0 5.84E+07 4.15E+07 - - - 4.3182 0.9751 221125_WJC_METTL3_EV_vs_WT_F01.18777.18777.2 0.757 14-Jun R.VPNAEEIF.- "sp|Q9BW92|SYTM_HUMAN,tr|F6S7Q7|F6S7Q7_HUMAN,tr|U3KQG0|U3KQG0_HUMAN" 3 917.4494 - 6387 18777 2 917.449714 459.732 "Threonine--tRNA ligase, mitochondrial OS=Homo sapiens OX=9606 GN=TARS2 PE=1 SV=1" 3.79 3588.2 - 1.27E+06 - - - 0.2899 - 0.98 0.143 - 95.9 1 2 0 0.0003 8 0 0 0 - - - - - 0.0362 0.9998 221125_WJC_METTL3_EV_vs_WT_F01.18778.18778.2 0.142 13/28 R.AILVDLEPGTMDSVR.S "sp|Q9BVA1|TBB2B_HUMAN,sp|P07437|TBB5_HUMAN,sp|Q13509|TBB3_HUMAN,sp|Q13885|TBB2A_HUMAN,tr|A0A0B4J269|A0A0B4J269_HUMAN,tr|Q5JP53|Q5JP53_HUMAN,tr|G3V3R4|G3V3R4_HUMAN,tr|G3V5W4|G3V5W4_HUMAN,tr|G3V2R8|G3V2R8_HUMAN,tr|G3V2N6|G3V2N6_HUMAN" 10 1614.8287 0.66 6388 18778 2 1614.828802 808.4216 Tubulin beta-2B chain OS=Homo sapiens OX=9606 GN=TUBB2B PE=1 SV=1 4.03 3588.3 - 928176 - - - 0.0582 - 2.822 0.391 - 362.2 1 2 0 0.0001 15 0 0 0 2.31E+07 3.53E+07 - - - 4.4795 0.956 221125_WJC_METTL3_EV_vs_WT_F01.18781.18781.2 4.39E-07 26-Nov R.PVELGFAESAPAWR[166.11].L "sp|Q16342|PDCD2_HUMAN,tr|J3QK82|J3QK82_HUMAN,tr|F5GWT2|F5GWT2_HUMAN,tr|A0A087WYJ3|A0A087WYJ3_HUMAN,tr|F5H4V9|F5H4V9_HUMAN" 5 1538.7757 1.7 6391 18781 2 1538.78078 770.3951 Programmed cell death protein 2 OS=Homo sapiens OX=9606 GN=PDCD2 PE=1 SV=2 4.53 3588.7 - 297680 - - - 3.3026 - 2.3 0.481 - 402.7 1 1 0 0.0051 14 0 0 0 3.72E+06 2.19E+06 - - - 4.6822 0.9911 221125_WJC_METTL3_EV_vs_WT_F01.18783.18783.2 0.0515 22-Jul R.YISPDQLADLYK.S "sp|P06733|ENOA_HUMAN,tr|A0A2R8Y6G6|A0A2R8Y6G6_HUMAN" 2 1424.7187 1.22 6393 18783 2 1424.723271 713.3666 Alpha-enolase OS=Homo sapiens OX=9606 GN=ENO1 PE=1 SV=2 4.21 3588.9 - 530775 - - - 3.1754 - 1.389 0.272 - 97 1 2 0 0.0045 12 0 0 0 1.62E+06 1.33E+06 - - - 1.9131 0.9853 221125_WJC_METTL3_EV_vs_WT_F01.18786.18786.2 0.344 14-Jul K.FITIFGTR[166.11].S "sp|P08758|ANXA5_HUMAN,tr|D6RBL5|D6RBL5_HUMAN,tr|D6RBE9|D6RBE9_HUMAN" 3 963.5417 1.97 6395 18786 2 963.544083 482.7781 Annexin A5 OS=Homo sapiens OX=9606 GN=ANXA5 PE=1 SV=2 9.75 3589.3 - 898158 - - - 2.4503 - 1.385 0.151 - 139.3 1 2 0 0.0024 8 0 0 0 2.45E+07 1.24E+07 - - - 1.1378 0.9999 221125_WJC_METTL3_EV_vs_WT_F01.18789.18789.2 0.00144 16-Oct K.FALNSLLQR[166.11].Q "sp|P39880|CUX1_HUMAN,tr|A0A2R8Y852|A0A2R8Y852_HUMAN" 2 1070.6112 1.41 6397 18789 2 1070.611135 536.3129 Homeobox protein cut-like 1 OS=Homo sapiens OX=9606 GN=CUX1 PE=1 SV=3 9.75 3589.5 - 3.45E+06 - - - -0.0598 - 1.979 0.471 - 401.7 1 2 0 -0.0001 9 0 0 0 5.84E+07 4.15E+07 - - - 4.4946 0.8783 221125_WJC_METTL3_EV_vs_WT_F01.18790.18790.2 0.171 18-Jun R.NGLQMHIK[136.11]AK[136.11].H "sp|P10074|TZAP_HUMAN,tr|K7EM76|K7EM76_HUMAN" 2 1154.6565 0.02 6398 18790 2 1154.654417 578.3355 Telomere zinc finger-associated protein OS=Homo sapiens OX=9606 GN=ZBTB48 PE=1 SV=2 10 3589.6 - 1.70E+06 - - - -1.8023 - 1.225 0.177 - 100.4 1 2 1 -0.0021 10 0 0 0 3.15E+05 2.02E+07 - - - 0.9141 0.9989 221125_WJC_METTL3_EV_vs_WT_F01.18791.18791.2 0.0205 14-Jun R.DLTDYLMK[136.11].L "sp|P63261|ACTG_HUMAN,sp|P68133|ACTS_HUMAN,sp|P62736|ACTA_HUMAN,sp|P68032|ACTC_HUMAN,sp|Q562R1|ACTBL_HUMAN,sp|P60709|ACTB_HUMAN,sp|P63267|ACTH_HUMAN,tr|A0A804GS07|A0A804GS07_HUMAN,tr|I3L3I0|I3L3I0_HUMAN,tr|E7EVS6|E7EVS6_HUMAN,tr|A0A6Q8PFE4|A0A6Q8PFE4_HUMAN,tr|I3L1U9|I3L1U9_HUMAN,tr|A0A2R8YEA7|A0A2R8YEA7_HUMAN,tr|A0A804HKV3|A0A804HKV3_HUMAN,tr|A0A2R8Y793|A0A2R8Y793_HUMAN,tr|I3L4N8|I3L4N8_HUMAN,tr|A6NL76|A6NL76_HUMAN" 17 1005.4932 0.96 6399 18791 2 1005.492403 503.7539 "Actin, cytoplasmic 2 OS=Homo sapiens OX=9606 GN=ACTG1 PE=1 SV=1" 4.21 3589.7 - 1.41E+06 - - - -0.8265 - 1.258 0.356 - 107.1 1 2 0 -0.0008 8 0 0 0 2.71E+08 2.81E+08 - - - 2.3624 1 221125_WJC_METTL3_EV_vs_WT_F01.18792.18792.2 4.01E-08 24-Dec R.TPFTTSQLLALER.K sp|P35548|MSX2_HUMAN 1 1475.7984 1.49 6400 18792 2 1475.798877 738.9065 Homeobox protein MSX-2 OS=Homo sapiens OX=9606 GN=MSX2 PE=1 SV=3 5.66 3589.8 - 1.32E+06 - - - 0.3273 - 2.841 0.626 - 594 1 2 0 0.0005 13 0 0 0 1.22E+07 8.19E+06 - - - 6.3443 0.9999 221125_WJC_METTL3_EV_vs_WT_F01.18793.18793.2 2.18E-05 18-Dec K.C[160.03]LEEFELLGK[136.11].A "sp|Q99613|EIF3C_HUMAN,sp|B5ME19|EIFCL_HUMAN,tr|H3BPE3|H3BPE3_HUMAN,tr|H3BPE4|H3BPE4_HUMAN,tr|H3BTY8|H3BTY8_HUMAN" 5 1244.6202 1.32 6401 18793 2 1244.621135 623.3174 Eukaryotic translation initiation factor 3 subunit C OS=Homo sapiens OX=9606 GN=EIF3C PE=1 SV=1 4.25 3589.9 - 938567 - - - 0.7311 - 2.307 0.547 - 438.3 1 2 0 0.0009 10 0 0 0 7.58E+06 5.73E+06 - - - 5.4142 0.9995 221125_WJC_METTL3_EV_vs_WT_F01.18796.18796.2 0.0102 12-Jul K.FGFIGFK.S sp|Q9Y4C8|RBM19_HUMAN 1 814.4378 1.07 6404 18796 2 814.437388 408.2262 Probable RNA-binding protein 19 OS=Homo sapiens OX=9606 GN=RBM19 PE=1 SV=3 8.75 3590.2 - 442199 - - - -0.458 - 1.576 0.35 - 134.2 1 2 0 -0.0004 7 0 0 0 3.63E+06 3.39E+06 - - - 3.0673 0.9963 221125_WJC_METTL3_EV_vs_WT_F01.18797.18797.2 0.0111 18-Aug R.LLLDTLQLSK.- "sp|O15357|SHIP2_HUMAN,tr|H7BXR2|H7BXR2_HUMAN" 2 1142.6911 0.61 6405 18797 2 1142.693443 572.3528 "Phosphatidylinositol 3,4,5-trisphosphate 5-phosphatase 2 OS=Homo sapiens OX=9606 GN=INPPL1 PE=1 SV=2" 5.84 3590.3 - 739813 - - - 2.0723 - 1.513 0.244 - 103.3 1 2 0 0.0024 10 0 0 0 2.44E+06 4.00E+06 - - - 1.9983 0.9998 221125_WJC_METTL3_EV_vs_WT_F01.18798.18798.2 5.49E-05 24-Dec R.LDYLGVSYGLTPR[166.11].L "sp|Q9H0A0|NAT10_HUMAN,tr|A0A087WV29|A0A087WV29_HUMAN" 2 1462.7695 0.78 6406 18798 2 1462.771672 732.3921 RNA cytidine acetyltransferase OS=Homo sapiens OX=9606 GN=NAT10 PE=1 SV=2 5.83 3590.4 - 363580 - - - 1.4507 - 2.227 0.526 - 380.4 1 2 0 0.0021 13 0 0 0 9.42E+06 1.21E+07 - - - 4.9803 0.9994 221125_WJC_METTL3_EV_vs_WT_F01.18799.18799.2 0.00138 20-Sep K.LLLNEDDYLIK[136.11].A "sp|Q52LR7|EPC2_HUMAN,tr|C9J1X4|C9J1X4_HUMAN,tr|E7ETK1|E7ETK1_HUMAN" 3 1355.7428 8.9 6407 18799 2 1355.743873 678.8787 Enhancer of polycomb homolog 2 OS=Homo sapiens OX=9606 GN=EPC2 PE=1 SV=2 4.03 3590.6 - 284777 - - - 0.804 - 1.716 0.336 - 248.1 1 2 0 0.0011 11 0 0 0 2.99E+07 3.36E+06 - - - 2.9832 0.9998 221125_WJC_METTL3_EV_vs_WT_F01.18800.18800.2 0.000449 24-Dec R.LDYLGVSYGLTPR.L "sp|Q9H0A0|NAT10_HUMAN,tr|A0A087WV29|A0A087WV29_HUMAN" 2 1452.7613 0.78 6408 18800 2 1452.763326 727.3879 RNA cytidine acetyltransferase OS=Homo sapiens OX=9606 GN=NAT10 PE=1 SV=2 5.83 3590.7 - 284754 - - - 1.4084 - 2.587 0.472 - 361.8 1 2 0 0.002 13 0 0 0 9.42E+06 1.21E+07 - - - 4.966 0.9999 221125_WJC_METTL3_EV_vs_WT_F01.18806.18806.2 3.06E-05 18-Oct K.SVVTSIFGVK[136.11].N "sp|P41252|SYIC_HUMAN,tr|A0A804HL54|A0A804HL54_HUMAN,tr|A0A804HJN6|A0A804HJN6_HUMAN,tr|A0A0A0MSX9|A0A0A0MSX9_HUMAN" 4 1043.6106 0.98 6413 18806 2 1043.611441 522.8126 "Isoleucine--tRNA ligase, cytoplasmic OS=Homo sapiens OX=9606 GN=IARS1 PE=1 SV=2" 8.47 3591.5 - 1.99E+06 - - - 0.7608 - 2.093 0.502 - 281.8 1 2 0 0.0008 10 0 0 0 2.93E+07 2.98E+07 - - - 4.8102 0.9997 221125_WJC_METTL3_EV_vs_WT_F01.18807.18807.2 0.00236 18-Sep R.LEPVIMELER[166.11].Q "sp|Q16875|F263_HUMAN,sp|O60825|F262_HUMAN,sp|P16118|F261_HUMAN,sp|Q16877|F264_HUMAN,tr|A0A1W2PR17|A0A1W2PR17_HUMAN,tr|I1Z9G3|I1Z9G3_HUMAN,tr|Q4VBA9|Q4VBA9_HUMAN,tr|Q66S35|Q66S35_HUMAN,tr|Q5W015|Q5W015_HUMAN,tr|F2Z2I2|F2Z2I2_HUMAN,tr|H0Y483|H0Y483_HUMAN,tr|Q5VX20|Q5VX20_HUMAN" 12 1237.6616 3.81 6414 18807 2 1237.661955 619.8381 "6-phosphofructo-2-kinase\fructose-2,6-bisphosphatase 3 OS=Homo sapiens OX=9606 GN=PFKFB3 PE=1 SV=1" 4.25 3591.6 - 3.50E+06 - - - 0.303 - 1.822 0.4 - 346.9 1 2 0 0.0004 10 0 0 0 1.17E+08 3.08E+07 - - - 3.6699 0.9959 221125_WJC_METTL3_EV_vs_WT_F01.18810.18810.2 0.0411 16-Aug K.GVILLIVDK.A "sp|P78344|IF4G2_HUMAN,tr|H0YE44|H0YE44_HUMAN,tr|H0YCF8|H0YCF8_HUMAN,tr|H0YEC5|H0YEC5_HUMAN,tr|H0Y3P2|H0Y3P2_HUMAN,tr|H0YCH5|H0YCH5_HUMAN,tr|H0YD77|H0YD77_HUMAN,tr|D3DQV9|D3DQV9_HUMAN" 8 968.627 1.67 6417 18810 2 968.626861 485.3208 Eukaryotic translation initiation factor 4 gamma 2 OS=Homo sapiens OX=9606 GN=EIF4G2 PE=1 SV=1 5.84 3591.7 - 2.23E+06 - - - -0.1631 - 1.639 0.105 - 183.5 1 2 0 -0.0002 9 0 0 0 2.29E+07 1.37E+07 - - - 1.2459 0.9995 221125_WJC_METTL3_EV_vs_WT_F01.18811.18811.2 0.0792 16-Sep K.GVILLIVDK[136.11].A "sp|P78344|IF4G2_HUMAN,tr|H0YE44|H0YE44_HUMAN,tr|H0YCF8|H0YCF8_HUMAN,tr|H0YEC5|H0YEC5_HUMAN,tr|H0Y3P2|H0Y3P2_HUMAN,tr|H0YCH5|H0YCH5_HUMAN,tr|H0YD77|H0YD77_HUMAN,tr|D3DQV9|D3DQV9_HUMAN" 8 976.6412 1.67 6418 18811 2 976.641083 489.3279 Eukaryotic translation initiation factor 4 gamma 2 OS=Homo sapiens OX=9606 GN=EIF4G2 PE=1 SV=1 5.84 3591.8 - 1.68E+06 - - - -0.1382 - 1.784 0.302 - 222.5 1 2 0 -0.0001 9 0 0 0 2.29E+07 1.37E+07 - - - 2.9462 0.9995 221125_WJC_METTL3_EV_vs_WT_F01.18813.18813.2 0.00342 18-Aug K.ILVPIQQVLK.E sp|P48723|HSP13_HUMAN 1 1149.7485 1.35 6420 18813 2 1149.748218 575.8815 Heat shock 70 kDa protein 13 OS=Homo sapiens OX=9606 GN=HSPA13 PE=1 SV=1 8.75 3592 - 1.03E+06 - - - -0.2722 - 1.446 0.391 - 159.9 1 2 0 -0.0003 10 0 0 0 9.10E+06 6.73E+06 - - - 2.9583 0.9061 221125_WJC_METTL3_EV_vs_WT_F01.18815.18815.2 30.1 14-Jun K.LAIVLFTK.E "sp|Q8NBN7|RDH13_HUMAN,tr|G8JLA1|G8JLA1_HUMAN" 2 903.5793 0.74 6422 18815 2 903.578254 452.7969 Retinol dehydrogenase 13 OS=Homo sapiens OX=9606 GN=RDH13 PE=1 SV=2 8.75 3592.2 - 598796 - - - -1.2019 - 1.134 0.028 - 73.9 5 2 0 -0.0011 8 0 0 0 1.36E+07 1.83E+07 - - - -0.6855 0.9989 221125_WJC_METTL3_EV_vs_WT_F01.18819.18819.2 0.00643 20-Sep K.ILVSLIEVAQK[136.11].L sp|Q9BSL1|UBAC1_HUMAN 1 1219.7631 1.01 6426 18819 2 1219.761752 610.8888 Ubiquitin-associated domain-containing protein 1 OS=Homo sapiens OX=9606 GN=UBAC1 PE=1 SV=1 6 3592.7 - 323992 - - - -1.1256 - 1.553 0.306 - 171 1 2 0 -0.0014 11 0 0 0 1.83E+06 1.81E+06 - - - 2.4915 0.9999 221125_WJC_METTL3_EV_vs_WT_F01.18822.18822.2 0.243 18-Oct R.LFDQAFGLPR[166.11].L "sp|P04792|HSPB1_HUMAN,tr|A0A6Q8PGY2|A0A6Q8PGY2_HUMAN,tr|A0A6Q8PHJ6|A0A6Q8PHJ6_HUMAN,tr|A0A6Q8PHA6|A0A6Q8PHA6_HUMAN,tr|A0A6Q8PF43|A0A6Q8PF43_HUMAN,tr|A0A6Q8PFK8|A0A6Q8PFK8_HUMAN,tr|A0A6Q8PGK1|A0A6Q8PGK1_HUMAN,tr|A0A6Q8PH65|A0A6Q8PH65_HUMAN,tr|A0A6Q8PFE7|A0A6Q8PFE7_HUMAN" 9 1172.6218 1.52 6428 18822 2 1172.621531 587.3182 Heat shock protein beta-1 OS=Homo sapiens OX=9606 GN=HSPB1 PE=1 SV=2 5.84 3593 - 4.27E+07 - - - -0.1987 - 2.087 0.49 - 435.8 1 2 0 -0.0002 10 0 0 0 7.66E+08 5.03E+08 - - - 4.7137 0.9997 221125_WJC_METTL3_EV_vs_WT_F01.18823.18823.2 0.0246 18-Aug R.LEPVIMELER.Q "sp|Q16875|F263_HUMAN,sp|O60825|F262_HUMAN,sp|P16118|F261_HUMAN,sp|Q16877|F264_HUMAN,tr|A0A1W2PR17|A0A1W2PR17_HUMAN,tr|I1Z9G3|I1Z9G3_HUMAN,tr|Q4VBA9|Q4VBA9_HUMAN,tr|Q66S35|Q66S35_HUMAN,tr|Q5W015|Q5W015_HUMAN,tr|F2Z2I2|F2Z2I2_HUMAN,tr|H0Y483|H0Y483_HUMAN,tr|Q5VX20|Q5VX20_HUMAN" 12 1227.6533 3.81 6429 18823 2 1227.652831 614.8339 "6-phosphofructo-2-kinase\fructose-2,6-bisphosphatase 3 OS=Homo sapiens OX=9606 GN=PFKFB3 PE=1 SV=1" 4.25 3593 - 1.27E+07 - - - -0.3902 - 1.738 0.405 - 249.6 1 2 0 -0.0005 10 0 0 0 1.17E+08 3.08E+07 - - - 3.575 0.9984 221125_WJC_METTL3_EV_vs_WT_F01.18824.18824.2 0.043 14-Jul R.DLTDYLMK.L "sp|P63261|ACTG_HUMAN,sp|P68133|ACTS_HUMAN,sp|P62736|ACTA_HUMAN,sp|P68032|ACTC_HUMAN,sp|Q562R1|ACTBL_HUMAN,sp|P60709|ACTB_HUMAN,sp|P63267|ACTH_HUMAN,tr|A0A804GS07|A0A804GS07_HUMAN,tr|I3L3I0|I3L3I0_HUMAN,tr|E7EVS6|E7EVS6_HUMAN,tr|A0A6Q8PFE4|A0A6Q8PFE4_HUMAN,tr|I3L1U9|I3L1U9_HUMAN,tr|A0A2R8YEA7|A0A2R8YEA7_HUMAN,tr|A0A804HKV3|A0A804HKV3_HUMAN,tr|A0A2R8Y793|A0A2R8Y793_HUMAN,tr|I3L4N8|I3L4N8_HUMAN,tr|A6NL76|A6NL76_HUMAN" 17 997.479 0.96 6430 18824 2 997.478896 499.7468 "Actin, cytoplasmic 2 OS=Homo sapiens OX=9606 GN=ACTG1 PE=1 SV=1" 4.21 3593.1 - 1.16E+07 - - - -0.1383 - 1.232 0.309 - 131.7 1 2 0 -0.0001 8 0 0 0 2.71E+08 2.81E+08 - - - 1.9525 0.9993 221125_WJC_METTL3_EV_vs_WT_F01.18828.18828.2 0.115 14-Oct K.LAIVLFTK[136.11].E "sp|Q8NBN7|RDH13_HUMAN,tr|G8JLA1|G8JLA1_HUMAN" 2 911.5935 0.74 6434 18828 2 911.593055 456.804 Retinol dehydrogenase 13 OS=Homo sapiens OX=9606 GN=RDH13 PE=1 SV=2 8.75 3593.3 - 1.67E+06 - - - -0.532 - 1.897 0.233 - 242.6 1 2 0 -0.0005 8 0 0 0 1.36E+07 1.83E+07 - - - 2.6928 0.9999 221125_WJC_METTL3_EV_vs_WT_F01.18829.18829.2 0.232 20-Dec K.MALDIEIATYR.K "sp|P08670|VIME_HUMAN,sp|P41219|PERI_HUMAN,tr|H7C5W5|H7C5W5_HUMAN,tr|B0YJC5|B0YJC5_HUMAN,tr|B0YJC4|B0YJC4_HUMAN" 5 1294.6591 1.69 6435 18829 2 1294.658224 648.3368 Vimentin OS=Homo sapiens OX=9606 GN=VIM PE=1 SV=4 4.37 3593.4 - 744944 - - - -0.6944 - 2.816 0.446 - 747.1 1 2 0 -0.0009 11 0 0 0 3.81E+07 2.25E+07 - - - 5.1357 1 221125_WJC_METTL3_EV_vs_WT_F01.18830.18830.3 0.000192 Dec-36 R.LFDQAFGLPR.L "sp|P04792|HSPB1_HUMAN,tr|A0A6Q8PGY2|A0A6Q8PGY2_HUMAN,tr|A0A6Q8PHJ6|A0A6Q8PHJ6_HUMAN,tr|A0A6Q8PHA6|A0A6Q8PHA6_HUMAN,tr|A0A6Q8PF43|A0A6Q8PF43_HUMAN,tr|A0A6Q8PFK8|A0A6Q8PFK8_HUMAN,tr|A0A6Q8PGK1|A0A6Q8PGK1_HUMAN,tr|A0A6Q8PH65|A0A6Q8PH65_HUMAN,tr|A0A6Q8PFE7|A0A6Q8PFE7_HUMAN" 9 1162.6135 1.85 6436 18830 3 1162.612068 388.5451 Heat shock protein beta-1 OS=Homo sapiens OX=9606 GN=HSPB1 PE=1 SV=2 5.84 3593.6 - 680103 - - - -1.2265 - 2.332 0.495 - 167.5 1 2 0 -0.0014 10 0 0 0 7.14E+06 3.85E+06 - - - 6.5312 0.9993 221125_WJC_METTL3_EV_vs_WT_F01.18831.18831.2 0.0867 14-Aug K.LDFNWVTR.W "sp|Q86W92|LIPB1_HUMAN,tr|F5GZP6|F5GZP6_HUMAN" 2 1049.5294 1.37 6437 18831 2 1049.529212 525.772 Liprin-beta-1 OS=Homo sapiens OX=9606 GN=PPFIBP1 PE=1 SV=2 5.84 3593.7 - 522301 - - - -0.2077 - 1.516 0.322 - 178.8 1 2 0 -0.0002 8 0 0 0 3.96E+06 2.89E+06 - - - 2.6741 0.9977 221125_WJC_METTL3_EV_vs_WT_F01.18833.18833.2 0.0961 24-Jul R.IELVVAPAGVTLK.E "sp|P20839|IMDH1_HUMAN,tr|C9J381|C9J381_HUMAN,tr|C9K0R9|C9K0R9_HUMAN,tr|A0A3B3IRL5|A0A3B3IRL5_HUMAN" 4 1308.8017 0.78 6439 18833 2 1308.80181 655.4081 Inosine-5'-monophosphate dehydrogenase 1 OS=Homo sapiens OX=9606 GN=IMPDH1 PE=1 SV=2 6 3594 - 252859 - - - 0.0932 - 1.645 0.187 - 94.3 1 2 0 0.0001 13 0 0 0 1.99E+06 2.57E+06 - - - 1.6996 0.8472 221125_WJC_METTL3_EV_vs_WT_F01.18834.18834.2 2.9 20-Jun R.LPPTEFAQLIK.R "sp|Q9Y2K2|SIK3_HUMAN,tr|H0Y4E8|H0Y4E8_HUMAN" 2 1255.7176 13.4 6440 18834 2 1255.719838 628.8661 Serine\threonine-protein kinase SIK3 OS=Homo sapiens OX=9606 GN=SIK3 PE=1 SV=4 6 3594.1 - 251134 - - - 1.7631 - 1.044 0.039 - 76.7 3 2 0 0.0022 11 0 0 0 3.38E+06 2.52E+05 - - - -0.7683 0.9996 221125_WJC_METTL3_EV_vs_WT_F01.18844.18844.2 0.000242 16-Sep R.LSYPTFFPR[166.11].F "sp|Q14527|HLTF_HUMAN,tr|A0A0C4DGA6|A0A0C4DGA6_HUMAN" 2 1136.5894 1.14 6448 18844 2 1136.587666 569.302 Helicase-like transcription factor OS=Homo sapiens OX=9606 GN=HLTF PE=1 SV=2 8.75 3595.2 - 581607 - - - -1.5265 - 1.744 0.436 - 227.5 1 2 0 -0.0017 9 0 0 0 3.05E+07 2.66E+07 - - - 3.8698 1 221125_WJC_METTL3_EV_vs_WT_F01.18845.18845.2 1.33E-10 13/24 R.LPMPEDYAMDELR.S "sp|P52948|NUP98_HUMAN,tr|H7C3P6|H7C3P6_HUMAN" 2 1578.7058 2.47 6449 18845 2 1578.704942 790.3602 Nuclear pore complex protein Nup98-Nup96 OS=Homo sapiens OX=9606 GN=NUP98 PE=1 SV=4 3.92 3595.3 - 376464 - - - -0.5536 - 2.59 0.707 - 506.2 1 2 0 -0.0009 13 0 0 0 4.68E+06 1.90E+06 - - - 6.7051 0.9993 221125_WJC_METTL3_EV_vs_WT_F01.18851.18851.2 0.217 16-Aug R.LQLPVWEYK[136.11].D sp|O43143|DHX15_HUMAN 1 1182.6528 1.03 6453 18851 2 1182.651766 592.3337 Pre-mRNA-splicing factor ATP-dependent RNA helicase DHX15 OS=Homo sapiens OX=9606 GN=DHX15 PE=1 SV=2 6 3596 - 3.54E+06 - - - -0.9132 - 1.658 0.321 - 255.5 1 2 0 -0.0011 9 0 0 0 7.00E+07 6.80E+07 - - - 2.8743 0.999 221125_WJC_METTL3_EV_vs_WT_F01.18852.18852.2 0.0134 16-Aug K.VFSIGPVFR[166.11].A sp|P14868|SYDC_HUMAN 1 1030.5839 0.98 6454 18852 2 1030.582865 516.2992 "Aspartate--tRNA ligase, cytoplasmic OS=Homo sapiens OX=9606 GN=DARS1 PE=1 SV=2" 9.72 3596.1 - 2.05E+06 - - - -1.0256 - 1.633 0.288 - 232.9 1 2 0 -0.0011 9 0 0 0 4.02E+07 4.11E+07 - - - 2.5866 0.9995 221125_WJC_METTL3_EV_vs_WT_F01.18856.18856.2 0.0147 16-Nov K.EAEILEVLR[166.11].H sp|P36551|HEM6_HUMAN 1 1080.6054 1.28 6458 18856 2 1080.602838 541.31 "Oxygen-dependent coproporphyrinogen-III oxidase, mitochondrial OS=Homo sapiens OX=9606 GN=CPOX PE=1 SV=3" 4.25 3596.4 - 1.10E+06 - - - -2.4125 - 2.258 0.388 - 459.8 1 2 0 -0.0026 9 0 0 0 3.78E+07 2.95E+07 - - - 4.2623 0.9926 221125_WJC_METTL3_EV_vs_WT_F01.18858.18858.2 1.36 12-Jul M.GLLSILR.K "sp|P36405|ARL3_HUMAN,sp|Q14517|FAT1_HUMAN,tr|A0A087WVP1|A0A087WVP1_HUMAN" 3 770.5014 0.87 6460 18858 2 770.50116 386.258 ADP-ribosylation factor-like protein 3 OS=Homo sapiens OX=9606 GN=ARL3 PE=1 SV=2 9.75 3596.6 - 477433 - - - -0.3426 - 1.385 0.102 - 184.5 1 2 0 -0.0003 7 0 0 0 4.40E+06 5.04E+06 - - - 0.8263 0.9826 221125_WJC_METTL3_EV_vs_WT_F01.18859.18859.2 0.117 12-Jul K.EFIEFLK.T "sp|Q9UJ41|RABX5_HUMAN,tr|E9PFK9|E9PFK9_HUMAN" 2 924.4957 0.59 6461 18859 2 924.494216 463.2551 Rab5 GDP\GTP exchange factor OS=Homo sapiens OX=9606 GN=RABGEF1 PE=1 SV=3 4.53 3596.8 - 319246 - - - -1.5727 - 1.322 0.087 - 137.1 1 2 0 -0.0015 7 0 0 0 2.98E+06 5.05E+06 - - - 0.5676 0.9988 221125_WJC_METTL3_EV_vs_WT_F01.18860.18860.2 0.00908 12-Aug K.EFIEFLK[136.11].T "sp|Q9UJ41|RABX5_HUMAN,tr|E9PFK9|E9PFK9_HUMAN" 2 932.5099 0.66 6462 18860 2 932.50782 467.2622 Rab5 GDP\GTP exchange factor OS=Homo sapiens OX=9606 GN=RABGEF1 PE=1 SV=3 4.53 3596.9 - 297666 - - - -2.1984 - 1.627 0.338 - 170.9 1 2 0 -0.002 7 0 0 0 2.98E+06 4.55E+06 - - - 3.0791 0.9807 221125_WJC_METTL3_EV_vs_WT_F01.18866.18866.2 0.00608 18-Sep K.SVPDEIILLR.S sp|Q9H9A6|LRC40_HUMAN 1 1153.6707 2.56 6466 18866 2 1153.672758 577.8426 Leucine-rich repeat-containing protein 40 OS=Homo sapiens OX=9606 GN=LRRC40 PE=1 SV=1 4.37 3597.6 - 4.35E+06 - - - 1.8064 - 1.692 0.038 - 320.3 2 2 0 0.0021 10 0 0 0 7.16E+07 2.80E+07 - - - 0.6545 0.9994 221125_WJC_METTL3_EV_vs_WT_F01.18868.18868.2 0.00747 16-Jul R.LSYPTFFPR.F "sp|Q14527|HLTF_HUMAN,tr|A0A0C4DGA6|A0A0C4DGA6_HUMAN" 2 1126.5811 1.14 6468 18868 2 1126.582017 564.2978 Helicase-like transcription factor OS=Homo sapiens OX=9606 GN=HLTF PE=1 SV=2 8.75 3597.7 - 1.23E+06 - - - 0.7865 - 1.526 0.367 - 133.4 1 2 0 0.0009 9 0 0 0 2.42E+07 2.12E+07 - - - 2.9741 0.9996 221125_WJC_METTL3_EV_vs_WT_F01.18869.18869.2 0.209 18-Dec K.LSLLLNDISR.K sp|Q15645|PCH2_HUMAN 1 1142.6659 0.2 6469 18869 2 1142.666808 572.3402 Pachytene checkpoint protein 2 homolog OS=Homo sapiens OX=9606 GN=TRIP13 PE=1 SV=2 5.84 3597.9 - 796488 - - - 0.7745 - 2.568 0.247 - 400.3 1 2 0 0.0009 10 0 0 0 8.92E+06 4.52E+07 - - - 3.4976 0.9809 221125_WJC_METTL3_EV_vs_WT_F01.18872.18872.2 2.69 12-Jun M.GLLSILR[166.11].K "sp|P36405|ARL3_HUMAN,sp|Q14517|FAT1_HUMAN,tr|A0A087WVP1|A0A087WVP1_HUMAN" 3 780.5097 0.87 6472 18872 2 780.509218 391.2621 ADP-ribosylation factor-like protein 3 OS=Homo sapiens OX=9606 GN=ARL3 PE=1 SV=2 9.75 3598.3 - 495304 - - - -0.6099 - 1.224 0.073 - 117.6 1 2 0 -0.0005 7 0 0 0 4.40E+06 5.04E+06 - - - 0.2205 0.9996 221125_WJC_METTL3_EV_vs_WT_F01.18876.18876.2 6.38E-07 24-Aug R.LPMPEDYAMDELR[166.11].S "sp|P52948|NUP98_HUMAN,tr|H7C3P6|H7C3P6_HUMAN" 2 1588.7141 2.47 6476 18876 2 1588.718109 795.3643 Nuclear pore complex protein Nup98-Nup96 OS=Homo sapiens OX=9606 GN=NUP98 PE=1 SV=4 3.92 3598.8 - 122561 - - - 2.5322 - 1.856 0.57 - 198.7 1 2 0 0.004 13 0 0 0 4.68E+06 1.90E+06 - - - 4.837 1 221125_WJC_METTL3_EV_vs_WT_F01.18880.18880.2 0.000762 20-Dec K.MALDIEIATYR[166.11].K "sp|P08670|VIME_HUMAN,sp|P41219|PERI_HUMAN,tr|H7C5W5|H7C5W5_HUMAN,tr|B0YJC5|B0YJC5_HUMAN,tr|B0YJC4|B0YJC4_HUMAN" 5 1304.6674 1.67 6478 18880 2 1304.669796 653.341 Vimentin OS=Homo sapiens OX=9606 GN=VIM PE=1 SV=4 4.37 3599.2 - 1.57E+06 - - - 1.8418 - 2.791 0.584 - 736.4 1 2 0 0.0024 11 0 0 0 3.96E+07 2.37E+07 - - - 6.1303 0.9998 221125_WJC_METTL3_EV_vs_WT_F01.18881.18881.2 0.00677 22-Dec K.GALPLDTVTFYK.V sp|P30040|ERP29_HUMAN 1 1323.7075 1.07 6479 18881 2 1323.708276 662.861 Endoplasmic reticulum resident protein 29 OS=Homo sapiens OX=9606 GN=ERP29 PE=1 SV=4 5.83 3599.4 - 1.01E+06 - - - 0.621 - 2.097 0.424 - 566.8 1 2 0 0.0008 12 0 0 0 1.25E+07 1.16E+07 - - - 4.1208 0.9999 221125_WJC_METTL3_EV_vs_WT_F01.18883.18883.2 1.58E-08 14/22 K.NIEDVIAQGIGK[136.11].L "sp|P05387|RLA2_HUMAN,tr|H0YDD8|H0YDD8_HUMAN" 2 1263.6914 0.96 6481 18883 2 1263.689619 632.853 60S acidic ribosomal protein P2 OS=Homo sapiens OX=9606 GN=RPLP2 PE=1 SV=1 4.37 3599.6 - 695622 - - - -1.422 - 2.459 0.525 - 484.6 1 2 0 -0.0018 12 0 0 0 8.30E+06 8.68E+06 - - - 5.2855 0.9943 221125_WJC_METTL3_EV_vs_WT_F01.18884.18884.2 0.00201 16-Jul K.LYQEMFAWK.M "sp|Q14204|DYHC1_HUMAN,tr|A0A7P0T8N2|A0A7P0T8N2_HUMAN,tr|A0A7P0T9C4|A0A7P0T9C4_HUMAN,tr|A0A7P0TBJ7|A0A7P0TBJ7_HUMAN,tr|A0A804HHY6|A0A804HHY6_HUMAN,tr|A0A7P0T9K2|A0A7P0T9K2_HUMAN,tr|A0A7P0TB64|A0A7P0TB64_HUMAN,tr|A0A2R8Y706|A0A2R8Y706_HUMAN,tr|A0A7P0T916|A0A7P0T916_HUMAN,tr|A0A7P0TB75|A0A7P0TB75_HUMAN,tr|A0A7P0T8W5|A0A7P0T8W5_HUMAN,tr|A0A7P0T9S3|A0A7P0T9S3_HUMAN,tr|A0A7P0TAF3|A0A7P0TAF3_HUMAN,tr|A0A7P0T9F1|A0A7P0T9F1_HUMAN,tr|A0A7P0TAW9|A0A7P0TAW9_HUMAN,tr|A0A2R8YGC7|A0A2R8YGC7_HUMAN,tr|A0A7P0TA13|A0A7P0TA13_HUMAN,tr|A0A7P0T934|A0A7P0T934_HUMAN,tr|A0A7P0TAV5|A0A7P0TAV5_HUMAN,tr|A0A7P0T9Y3|A0A7P0T9Y3_HUMAN,tr|A0A7P0T7V5|A0A7P0T7V5_HUMAN,tr|A0A7P0T9R4|A0A7P0T9R4_HUMAN,tr|A0A2R8Y5T0|A0A2R8Y5T0_HUMAN,tr|A0A7P0T990|A0A7P0T990_HUMAN,tr|A0A7P0T942|A0A7P0T942_HUMAN,tr|A0A2R8YFZ7|A0A2R8YFZ7_HUMAN,tr|A0A7P0T825|A0A7P0T825_HUMAN,tr|A0A2R8Y6H2|A0A2R8Y6H2_HUMAN,tr|A0A7P0TBC9|A0A7P0TBC9_HUMAN,tr|A0A7P0TAM4|A0A7P0TAM4_HUMAN" 30 1214.5794 1.72 6482 18884 2 1214.580701 608.297 Cytoplasmic dynein 1 heavy chain 1 OS=Homo sapiens OX=9606 GN=DYNC1H1 PE=1 SV=5 6 3599.7 - 462856 - - - 1.058 - 1.558 0.123 - 107 1 2 0 0.0013 9 0 0 0 8.30E+06 4.83E+06 - - - 1.2319 0.9999 221125_WJC_METTL3_EV_vs_WT_F01.18890.18890.2 2.03E-06 18-Sep K.YPYMVEWYTK.S "sp|Q9H0P0|5NT3A_HUMAN,tr|B9A035|B9A035_HUMAN,tr|X6RM59|X6RM59_HUMAN" 3 1378.6268 4.81 6488 18890 2 1378.625176 690.3207 Cytosolic 5'-nucleotidase 3A OS=Homo sapiens OX=9606 GN=NT5C3A PE=1 SV=3 6 3600.5 - 241399 - - - -1.1497 - 2.103 0.605 - 239.4 1 2 0 -0.0016 10 0 0 0 3.00E+06 6.23E+05 - - - 5.584 0.9237 221125_WJC_METTL3_EV_vs_WT_F01.18892.18892.2 0.00897 26-Jun R.YILPDEPAIIVHPN.W "sp|Q8IX12|CCAR1_HUMAN,tr|H0YFJ7|H0YFJ7_HUMAN,tr|F5H2E6|F5H2E6_HUMAN,tr|F5H1H2|F5H1H2_HUMAN,tr|A0A0C4DGG8|A0A0C4DGG8_HUMAN" 5 1589.8453 - 6490 18892 2 1589.845388 795.9299 Cell division cycle and apoptosis regulator protein 1 OS=Homo sapiens OX=9606 GN=CCAR1 PE=1 SV=2 4.35 3600.8 - 171758 - - - 0.0277 - 1.314 0.321 - 61.8 1 1 0 0 14 0 0 0 - - - - - 2.0972 0.9997 221125_WJC_METTL3_EV_vs_WT_F01.18897.18897.2 0.00383 16-Sep K.VFSIGPVFR.A sp|P14868|SYDC_HUMAN 1 1020.5757 0.97 6493 18897 2 1020.576346 511.2951 "Aspartate--tRNA ligase, cytoplasmic OS=Homo sapiens OX=9606 GN=DARS1 PE=1 SV=2" 9.72 3601.3 - 4.26E+06 - - - 0.68 - 1.798 0.404 - 314.7 1 2 0 0.0007 9 0 0 0 4.04E+07 4.17E+07 - - - 3.722 0.9387 221125_WJC_METTL3_EV_vs_WT_F01.18913.18913.2 1.42 14-Apr R.NGMAFLAC[160.03].- "sp|O75486|SUPT3_HUMAN,tr|A0A6I8PRV1|A0A6I8PRV1_HUMAN" 2 882.3728 - 6509 18913 2 882.373267 442.1937 Transcription initiation protein SPT3 homolog OS=Homo sapiens OX=9606 GN=SUPT3H PE=1 SV=3 5.52 3603.2 - 220387 - - - 0.5349 - 0.706 0.203 - 39 1 2 0 0.0005 8 0 0 0 - - - - - -0.5098 0.9998 221125_WJC_METTL3_EV_vs_WT_F01.18917.18917.2 5.97E-05 18-Oct K.SVPDEIILLR[166.11].S sp|Q9H9A6|LRC40_HUMAN 1 1163.6789 2.57 6511 18917 2 1163.67981 582.8467 Leucine-rich repeat-containing protein 40 OS=Homo sapiens OX=9606 GN=LRRC40 PE=1 SV=1 4.37 3603.7 - 1.97E+06 - - - 0.7442 - 1.871 0.451 - 444.4 1 2 0 0.0009 10 0 0 0 7.04E+07 2.74E+07 - - - 4.1205 0.9999 221125_WJC_METTL3_EV_vs_WT_F01.18918.18918.2 0.000101 22-Dec K.LSTIALALGVER[166.11].T "sp|P30153|2AAA_HUMAN,sp|P30154|2AAB_HUMAN,tr|C9J9C1|C9J9C1_HUMAN,tr|E9PHZ6|E9PHZ6_HUMAN,tr|E9PPI5|E9PPI5_HUMAN,tr|E9PNM7|E9PNM7_HUMAN" 6 1251.7426 0.74 6512 18918 2 1251.742908 626.8786 Serine\threonine-protein phosphatase 2A 65 kDa regulatory subunit A alpha isoform OS=Homo sapiens OX=9606 GN=PPP2R1A PE=1 SV=4 6 3603.8 - 1.57E+06 - - - 0.2405 - 2.465 0.462 - 537.1 1 2 0 0.0003 12 0 0 0 3.16E+07 4.25E+07 - - - 4.8271 0.9943 221125_WJC_METTL3_EV_vs_WT_F01.18920.18920.2 0.000289 22-Dec K.LSTIALALGVER.T "sp|P30153|2AAA_HUMAN,sp|P30154|2AAB_HUMAN,tr|C9J9C1|C9J9C1_HUMAN,tr|E9PHZ6|E9PHZ6_HUMAN,tr|E9PPI5|E9PPI5_HUMAN,tr|E9PNM7|E9PNM7_HUMAN" 6 1241.7343 0.74 6514 18920 2 1241.740738 621.8744 Serine\threonine-protein phosphatase 2A 65 kDa regulatory subunit A alpha isoform OS=Homo sapiens OX=9606 GN=PPP2R1A PE=1 SV=4 6 3604 - 1.02E+06 - - - 5.1549 - 2.408 0.326 - 509.6 1 2 0 0.0064 12 0 0 0 3.16E+07 4.25E+07 - - - 3.7591 0.9999 221125_WJC_METTL3_EV_vs_WT_F01.18923.18923.2 8.73E-06 18-Nov R.LWIANYSLPR.A sp|O43172|PRP4_HUMAN 1 1231.6713 3.1 6517 18923 2 1231.670856 616.8429 U4\U6 small nuclear ribonucleoprotein Prp4 OS=Homo sapiens OX=9606 GN=PRPF4 PE=1 SV=2 8.75 3604.3 - 727782 - - - -0.3954 - 2.328 0.509 - 612.4 1 2 0 -0.0005 10 0 0 0 2.18E+08 7.04E+07 - - - 5.159 0.9994 221125_WJC_METTL3_EV_vs_WT_F01.18926.18926.2 0.00398 16-Sep R.LDGFSVLMR[166.11].A sp|Q9NZL4|HPBP1_HUMAN 1 1046.5458 0.45 6520 18926 2 1046.546554 524.2802 Hsp70-binding protein 1 OS=Homo sapiens OX=9606 GN=HSPBP1 PE=1 SV=2 5.84 3604.6 - 426274 - - - 0.6994 - 1.764 0.314 - 175.7 1 2 0 0.0007 9 0 0 0 9.61E+06 2.13E+07 - - - 3.002 0.9996 221125_WJC_METTL3_EV_vs_WT_F01.18927.18927.2 0.000586 22-Sep K.YPYWPHQPIENL.- sp|O75947|ATP5H_HUMAN 1 1555.746 - 6521 18927 2 1555.748436 778.8803 "ATP synthase subunit d, mitochondrial OS=Homo sapiens OX=9606 GN=ATP5PD PE=1 SV=3" 5.24 3604.8 - 418922 - - - 1.5883 - 1.816 0.457 - 167.3 1 2 0 0.0025 12 0 0 0 - - - - - 3.9855 0.9986 221125_WJC_METTL3_EV_vs_WT_F01.18928.18928.2 0.00028 24-Oct K.FIAELGVPLSQVK[136.11].S sp|Q86T24|KAISO_HUMAN 1 1407.8217 0.17 6522 18928 2 1407.826372 704.9181 Transcriptional regulator Kaiso OS=Homo sapiens OX=9606 GN=ZBTB33 PE=1 SV=2 6 3604.9 - 264269 - - - 3.3172 - 1.79 0.448 - 248.8 1 2 0 0.0047 13 0 0 0 6.23E+05 3.70E+06 - - - 3.8427 0.9978 221125_WJC_METTL3_EV_vs_WT_F01.18933.18933.2 0.00594 18-Aug R.IIVAIDGWPR.N "sp|Q9Y2L1|RRP44_HUMAN,tr|F2Z2C0|F2Z2C0_HUMAN,tr|G3V1J5|G3V1J5_HUMAN" 3 1138.6499 1.59 6525 18933 2 1138.650329 570.3322 Exosome complex exonuclease RRP44 OS=Homo sapiens OX=9606 GN=DIS3 PE=1 SV=2 5.84 3605.6 - 3.97E+06 - - - 0.3952 - 1.954 0.116 - 187.4 1 2 0 0.0004 10 0 0 0 1.04E+08 6.55E+07 - - - 1.7675 0.9998 221125_WJC_METTL3_EV_vs_WT_F01.18935.18935.2 0.0142 18-Oct R.IIVAIDGWPR[166.11].N "sp|Q9Y2L1|RRP44_HUMAN,tr|F2Z2C0|F2Z2C0_HUMAN,tr|G3V1J5|G3V1J5_HUMAN" 3 1148.6581 1.57 6527 18935 2 1148.659157 575.3364 Exosome complex exonuclease RRP44 OS=Homo sapiens OX=9606 GN=DIS3 PE=1 SV=2 5.84 3605.7 - 3.26E+06 - - - 0.8775 - 2.172 0.394 - 311.8 1 2 0 0.001 10 0 0 0 1.03E+08 6.55E+07 - - - 4.1158 0.9342 221125_WJC_METTL3_EV_vs_WT_F01.18936.18936.2 0.247 12-Jun K.QFLDYFK[136.11].T "sp|P22314|UBA1_HUMAN,tr|Q5JRR6|Q5JRR6_HUMAN" 2 967.4895 0.46 6528 18936 2 967.490815 484.752 Ubiquitin-like modifier-activating enzyme 1 OS=Homo sapiens OX=9606 GN=UBA1 PE=1 SV=3 5.83 3605.8 - 2.00E+06 - - - 1.3912 - 1.125 0.036 - 143.4 1 2 0 0.0013 7 0 0 0 7.10E+06 1.53E+07 - - - -0.3203 0.9998 221125_WJC_METTL3_EV_vs_WT_F01.18937.18937.2 0.000864 16-Sep K.DIVENYFMR.D "sp|Q13263|TIF1B_HUMAN,tr|M0R2I3|M0R2I3_HUMAN" 2 1185.5488 0.68 6529 18937 2 1185.550069 593.7817 Transcription intermediary factor 1-beta OS=Homo sapiens OX=9606 GN=TRIM28 PE=1 SV=5 4.37 3605.8 - 1.80E+06 - - - 1.0324 - 2.08 0.46 - 270.7 1 2 0 0.0012 9 0 0 0 2.30E+07 3.36E+07 - - - 4.557 0.9695 221125_WJC_METTL3_EV_vs_WT_F01.18942.18942.2 0.0115 12-Sep K.ITDFIKF.D sp|P62701|RS4X_HUMAN 1 882.4851 0.76 6534 18942 2 882.485794 442.2498 "40S ribosomal protein S4, X isoform OS=Homo sapiens OX=9606 GN=RPS4X PE=1 SV=2" 5.84 3606.2 - 766861 - - - 0.7807 - 1.814 0.303 - 176.2 1 1 0 0.0007 7 0 0 0 1.29E+07 1.71E+07 - - - 3.1657 0.9991 221125_WJC_METTL3_EV_vs_WT_F01.18946.18946.2 0.0118 14-Sep R.WALGQVFR[166.11].Q "sp|P26572|MGAT1_HUMAN,tr|D6RF69|D6RF69_HUMAN" 2 985.5373 1.45 6538 18946 2 985.538785 493.7759 "Alpha-1,3-mannosyl-glycoprotein 2-beta-N-acetylglucosaminyltransferase OS=Homo sapiens OX=9606 GN=MGAT1 PE=1 SV=2" 9.75 3606.6 - 589864 - - - 1.5007 - 1.866 0.281 - 363.5 1 2 0 0.0015 8 0 0 0 1.09E+07 7.51E+06 - - - 2.9973 0.9814 221125_WJC_METTL3_EV_vs_WT_F01.18947.18947.2 0.0575 16-Jun R.YVALTSLLK.T sp|O43747|AP1G1_HUMAN 1 1006.6063 0.89 6539 18947 2 1006.607513 504.3104 AP-1 complex subunit gamma-1 OS=Homo sapiens OX=9606 GN=AP1G1 PE=1 SV=5 8.59 3606.7 - 538380 - - - 1.2219 - 1.032 0.18 - 67.7 1 2 0 0.0012 9 0 0 0 4.39E+06 4.93E+06 - - - 0.4612 0.9999 221125_WJC_METTL3_EV_vs_WT_F01.18948.18948.2 0.0032 13/20 K.LLEVQILEVQR.A "sp|Q8IWJ2|GCC2_HUMAN,tr|H7BYJ9|H7BYJ9_HUMAN" 2 1338.7871 2.36 6540 18948 2 1338.786452 670.4008 GRIP and coiled-coil domain-containing protein 2 OS=Homo sapiens OX=9606 GN=GCC2 PE=1 SV=4 4.53 3606.9 - 375768 - - - -0.4848 - 2.419 0.473 - 817.1 1 2 0 -0.0006 11 0 0 0 6.58E+06 2.79E+06 - - - 4.9241 0.9997 221125_WJC_METTL3_EV_vs_WT_F01.18956.18956.2 0.0122 12-Aug R.SGMFWLR.F sp|P31930|QCR1_HUMAN 1 895.4374 1.17 6546 18956 2 895.437369 448.726 "Cytochrome b-c1 complex subunit 1, mitochondrial OS=Homo sapiens OX=9606 GN=UQCRC1 PE=1 SV=3" 9.47 3607.9 - 1.87E+06 - - - -0.0838 - 1.597 0.422 - 291.5 1 2 0 -0.0001 7 0 0 0 1.40E+07 1.20E+07 - - - 3.6412 0.9715 221125_WJC_METTL3_EV_vs_WT_F01.18958.18958.2 0.0103 12-Jul K.ITDFIK[136.11]F.D sp|P62701|RS4X_HUMAN 1 890.4993 0.76 6548 18958 2 890.499565 446.2569 "40S ribosomal protein S4, X isoform OS=Homo sapiens OX=9606 GN=RPS4X PE=1 SV=2" 5.84 3608 - 1.91E+06 - - - 0.292 - 1.576 0.352 - 93.5 1 1 0 0.0003 7 0 0 0 1.31E+07 1.73E+07 - - - 3.0821 0.8571 221125_WJC_METTL3_EV_vs_WT_F01.18960.18960.2 0.00473 22-Aug K.GPAVGIDLGTTY.S "sp|P11142|HSP7C_HUMAN,tr|E9PQQ4|E9PQQ4_HUMAN,tr|E9PNE6|E9PNE6_HUMAN,tr|E9PKE3|E9PKE3_HUMAN,tr|E9PLF4|E9PLF4_HUMAN,tr|E9PI65|E9PI65_HUMAN,tr|E9PK54|E9PK54_HUMAN,tr|E9PN25|E9PN25_HUMAN,tr|E9PPY6|E9PPY6_HUMAN,tr|E9PQK7|E9PQK7_HUMAN" 10 1162.587 - 6550 18960 2 1162.584569 582.3008 Heat shock cognate 71 kDa protein OS=Homo sapiens OX=9606 GN=HSPA8 PE=1 SV=1 3.8 3608.2 - 1.48E+06 - - - -2.0945 - 1.333 0.327 - 165.9 1 1 0 -0.0024 12 0 0 0 - - - - - 2.2117 0.9995 221125_WJC_METTL3_EV_vs_WT_F01.18961.18961.2 0.0016 14-Aug R.WALGQVFR.Q "sp|P26572|MGAT1_HUMAN,tr|D6RF69|D6RF69_HUMAN" 2 975.529 1.26 6551 18961 2 975.530383 488.7718 "Alpha-1,3-mannosyl-glycoprotein 2-beta-N-acetylglucosaminyltransferase OS=Homo sapiens OX=9606 GN=MGAT1 PE=1 SV=2" 9.75 3608.2 - 1.29E+06 - - - 1.3808 - 1.606 0.403 - 189.2 1 2 0 0.0013 8 0 0 0 1.15E+07 9.15E+06 - - - 3.4459 0.9994 221125_WJC_METTL3_EV_vs_WT_F01.18963.18963.2 0.0165 18-Jul R.FMEPYIFGSR[166.11].L "sp|Q9Y399|RT02_HUMAN,tr|Q5T8A0|Q5T8A0_HUMAN" 2 1255.5935 1.11 6553 18963 2 1255.595408 628.804 "28S ribosomal protein S2, mitochondrial OS=Homo sapiens OX=9606 GN=MRPS2 PE=1 SV=1" 6 3608.4 - 1.69E+06 - - - 1.5196 - 1.645 0.401 - 205.2 1 2 0 0.0019 10 0 0 0 8.90E+06 8.05E+06 - - - 3.3915 0.9992 221125_WJC_METTL3_EV_vs_WT_F01.18966.18966.2 0.138 22-Nov R.AALEALLPYTER.H "sp|Q12788|TBL3_HUMAN,tr|J3KNP2|J3KNP2_HUMAN" 2 1345.7242 1.1 6556 18966 2 1345.727352 673.8694 Transducin beta-like protein 3 OS=Homo sapiens OX=9606 GN=TBL3 PE=1 SV=2 4.53 3608.8 - 501499 - - - 2.3675 - 2.511 0.303 - 500 1 2 0 0.0032 12 0 0 0 1.13E+07 1.03E+07 - - - 3.7004 0.9999 221125_WJC_METTL3_EV_vs_WT_F01.18967.18967.3 0.00131 Dec-36 R.LWIANYSLPR.A sp|O43172|PRP4_HUMAN 1 1231.6713 2.6 6557 18967 3 1231.671806 411.5644 U4\U6 small nuclear ribonucleoprotein Prp4 OS=Homo sapiens OX=9606 GN=PRPF4 PE=1 SV=2 8.75 3608.9 - 501011 - - - 0.3759 - 2.243 0.367 - 257.6 1 2 0 0.0005 10 0 0 0 5.31E+06 2.04E+06 - - - 4.9907 0.999 221125_WJC_METTL3_EV_vs_WT_F01.18971.18971.3 0.0435 Oct-44 K.LSTIALALGVER.T "sp|P30153|2AAA_HUMAN,sp|P30154|2AAB_HUMAN,tr|C9J9C1|C9J9C1_HUMAN,tr|E9PHZ6|E9PHZ6_HUMAN,tr|E9PPI5|E9PPI5_HUMAN,tr|E9PNM7|E9PNM7_HUMAN" 6 1241.7343 0.68 6561 18971 3 1241.735147 414.9187 Serine\threonine-protein phosphatase 2A 65 kDa regulatory subunit A alpha isoform OS=Homo sapiens OX=9606 GN=PPP2R1A PE=1 SV=4 6 3609.4 - 353072 - - - 0.6523 - 1.639 0.307 - 86.7 1 2 0 0.0008 12 0 0 0 2.22E+06 3.24E+06 - - - 3.3321 0.9973 221125_WJC_METTL3_EV_vs_WT_F01.18974.18974.2 0.0149 22-Oct R.IFSLSGTLETVR.G "sp|Q9Y2S7|PDIP2_HUMAN,tr|B4DEM9|B4DEM9_HUMAN" 2 1321.7242 0.59 6564 18974 2 1321.727396 661.8694 Polymerase delta-interacting protein 2 OS=Homo sapiens OX=9606 GN=POLDIP2 PE=1 SV=1 6 3609.8 - 162759 - - - 2.4438 - 1.689 0.279 - 174.2 1 2 0 0.0032 12 0 0 0 2.11E+06 3.56E+06 - - - 2.4798 0.9999 221125_WJC_METTL3_EV_vs_WT_F01.18978.18978.2 3.62E-05 16-Nov R.QINWTVLYR.R "sp|P83731|RL24_HUMAN,tr|C9JNW5|C9JNW5_HUMAN,tr|C9JXB8|C9JXB8_HUMAN" 3 1191.64 0.99 6566 18978 2 1191.640345 596.8273 60S ribosomal protein L24 OS=Homo sapiens OX=9606 GN=RPL24 PE=1 SV=1 8.75 3610.2 - 3.36E+06 - - - 0.2534 - 2.411 0.474 - 796.4 1 2 0 0.0003 9 0 0 0 3.53E+07 3.56E+07 - - - 5.0879 0.9932 221125_WJC_METTL3_EV_vs_WT_F01.18979.18979.2 1.52E-05 13/38 K.LLAAYPGASGLGSAAAAAAA.A sp|Q9H7S9|ZN703_HUMAN 1 1672.8784 - 6567 18979 2 1672.87776 837.4465 Zinc finger protein 703 OS=Homo sapiens OX=9606 GN=ZNF703 PE=1 SV=1 5.52 3610.3 - 1.42E+06 - - - -0.4035 - 2.494 0.501 - 359.9 1 1 0 -0.0007 20 0 0 0 - - - - - 4.988 0.9998 221125_WJC_METTL3_EV_vs_WT_F01.18980.18980.2 0.000145 13/20 R.TSLALDESLFR.G "sp|Q86U42|PABP2_HUMAN,tr|B4DEH8|B4DEH8_HUMAN,tr|G3V4T2|G3V4T2_HUMAN,tr|H0YJH9|H0YJH9_HUMAN,tr|A0A7I2V383|A0A7I2V383_HUMAN" 5 1250.6507 1.63 6568 18980 2 1250.651861 626.3326 Polyadenylate-binding protein 2 OS=Homo sapiens OX=9606 GN=PABPN1 PE=1 SV=3 4.37 3610.4 - 3.21E+06 - - - 0.9547 - 2.529 0.428 - 809.9 1 2 0 0.0012 11 0 0 0 8.66E+07 5.32E+07 - - - 4.7118 0.9141 221125_WJC_METTL3_EV_vs_WT_F01.18981.18981.2 0.000297 16-Sep S.GDLLSEVER[166.11].N "sp|O14513|NCKP5_HUMAN,tr|A0A0A0MSE4|A0A0A0MSE4_HUMAN,tr|A0A0A0MS79|A0A0A0MS79_HUMAN" 3 1026.5221 0.28 6569 18981 2 1026.524869 514.2683 Nck-associated protein 5 OS=Homo sapiens OX=9606 GN=NCKAP5 PE=1 SV=2 4.14 3610.4 - 1.68E+06 - - - 2.6887 - 1.943 0.302 - 373.3 1 1 0 0.0028 9 0 0 0 1.13E+07 4.07E+07 - - - 3.1924 1 221125_WJC_METTL3_EV_vs_WT_F01.18984.18984.2 1.24E-07 14/22 R.VVYSAFLMATPR.L sp|Q15029|U5S1_HUMAN 1 1353.7115 1.74 6572 18984 2 1353.711582 677.863 116 kDa U5 small nuclear ribonucleoprotein component OS=Homo sapiens OX=9606 GN=EFTUD2 PE=1 SV=1 8.72 3610.7 - 714041 - - - 0.0657 - 2.651 0.588 - 802.2 1 2 0 0.0001 12 0 0 0 2.05E+07 1.18E+07 - - - 5.9492 0.9977 221125_WJC_METTL3_EV_vs_WT_F01.18986.18986.2 0.0739 12-Jul R.DYLQLLR[166.11].K sp|L0R6Q1|S35U4_HUMAN 1 929.521 1.68 6574 18986 2 929.521909 465.7678 SLC35A4 upstream open reading frame protein OS=Homo sapiens OX=9606 GN=SLC35A4 PE=3 SV=1 5.84 3610.9 - 494421 - - - 0.9919 - 1.346 0.26 - 183.8 1 2 0 0.0009 7 0 0 0 5.86E+06 3.48E+06 - - - 1.9026 0.9999 221125_WJC_METTL3_EV_vs_WT_F01.18987.18987.2 5.53E-07 22-Dec R.VVYSAFLMATPR[166.11].L sp|Q15029|U5S1_HUMAN 1 1363.7198 1.74 6575 18987 2 1363.719498 682.8672 116 kDa U5 small nuclear ribonucleoprotein component OS=Homo sapiens OX=9606 GN=EFTUD2 PE=1 SV=1 8.72 3611.1 - 427112 - - - -0.1943 - 2.156 0.545 - 602.7 1 2 0 -0.0003 12 0 0 0 2.05E+07 1.18E+07 - - - 5.0877 0.9996 221125_WJC_METTL3_EV_vs_WT_F01.18991.18991.2 0.0216 16-Aug R.YLDVSILGK[136.11].F sp|Q86U44|MTA70_HUMAN 1 1014.5841 0.39 6578 18991 2 1014.584956 508.2993 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 5.83 3611.6 - 1.44E+06 - - - 0.8457 - 1.779 0.396 - 131.5 1 2 0 0.0009 9 0 0 0 9.77E+06 2.52E+07 - - - 3.6321 0.9997 221125_WJC_METTL3_EV_vs_WT_F01.18993.18993.2 0.000383 18-Sep R.SIPMTVDFIR.L sp|P00492|HPRT_HUMAN 1 1177.6165 0.69 6580 18993 2 1177.615321 589.8155 Hypoxanthine-guanine phosphoribosyltransferase OS=Homo sapiens OX=9606 GN=HPRT1 PE=1 SV=2 5.55 3611.9 - 1.57E+06 - - - -1.0266 - 1.89 0.42 - 326.9 1 2 0 -0.0012 10 0 0 0 2.00E+07 2.91E+07 - - - 3.9196 0.9997 221125_WJC_METTL3_EV_vs_WT_F01.18994.18994.2 0.00767 16-Oct R.VLEALLPLK[136.11].G "sp|P49327|FAS_HUMAN,tr|A0A0U1RQF0|A0A0U1RQF0_HUMAN" 2 1002.6569 0.65 6581 18994 2 1002.65674 502.3357 Fatty acid synthase OS=Homo sapiens OX=9606 GN=FASN PE=1 SV=3 5.97 3612 - 811258 - - - -0.1287 - 1.829 0.371 - 295.5 1 2 0 -0.0001 9 0 0 0 4.39E+07 6.76E+07 - - - 3.5279 0.9999 221125_WJC_METTL3_EV_vs_WT_F01.18996.18996.2 4.33E-06 13/20 K.YATLSLFNTYK.G "sp|Q9Y520|PRC2C_HUMAN,tr|E7EPN9|E7EPN9_HUMAN" 2 1319.6762 0.91 6583 18996 2 1319.676547 660.8454 Protein PRRC2C OS=Homo sapiens OX=9606 GN=PRRC2C PE=1 SV=4 8.5 3612.2 - 599315 - - - 0.2978 - 2.289 0.529 - 531.6 1 2 0 0.0004 11 0 0 0 9.75E+06 1.08E+07 - - - 5.1883 0.9998 221125_WJC_METTL3_EV_vs_WT_F01.19008.19008.2 1.54E-06 16-Aug K.MDLVTYFGK[136.11].R sp|P09543|CN37_HUMAN 1 1080.5405 0.23 6593 19008 2 1080.542117 541.2775 "2',3'-cyclic-nucleotide 3'-phosphodiesterase OS=Homo sapiens OX=9606 GN=CNP PE=1 SV=2" 5.59 3613.6 - 1.29E+06 - - - 1.4798 - 2.025 0.541 - 264.9 1 2 0 0.0016 9 0 0 0 4.56E+06 2.00E+07 - - - 5.0776 0.9998 221125_WJC_METTL3_EV_vs_WT_F01.19009.19009.2 0.0223 16-Oct R.VLEALLPLK.G "sp|P49327|FAS_HUMAN,tr|A0A0U1RQF0|A0A0U1RQF0_HUMAN" 2 994.6427 0.65 6594 19009 2 994.642556 498.3286 Fatty acid synthase OS=Homo sapiens OX=9606 GN=FASN PE=1 SV=3 5.97 3613.6 - 1.16E+06 - - - -0.1136 - 1.971 0.385 - 324.8 1 2 0 -0.0001 9 0 0 0 4.39E+07 6.76E+07 - - - 3.8476 0.8879 221125_WJC_METTL3_EV_vs_WT_F01.19010.19010.2 5.04 14-May R.QWELLLEK.M "sp|Q13813|SPTN1_HUMAN,tr|A0A0D9SFF6|A0A0D9SFF6_HUMAN,tr|A0A0D9SF54|A0A0D9SF54_HUMAN,tr|A0A0D9SGF6|A0A0D9SGF6_HUMAN,tr|A0A5F9ZHC3|A0A5F9ZHC3_HUMAN" 5 1057.5808 1.21 6595 19010 2 1057.581355 529.7977 "Spectrin alpha chain, non-erythrocytic 1 OS=Homo sapiens OX=9606 GN=SPTAN1 PE=1 SV=3" 4.53 3613.7 - 1.14E+06 - - - 0.5276 - 1.042 0.036 - 57.4 6 2 0 0.0006 8 0 0 0 1.37E+07 1.13E+07 - - - -0.9168 0.9994 221125_WJC_METTL3_EV_vs_WT_F01.19011.19011.2 0.000379 20-Nov K.YATLSLFNTYK[136.11].G "sp|Q9Y520|PRC2C_HUMAN,tr|E7EPN9|E7EPN9_HUMAN" 2 1327.6904 0.88 6596 19011 2 1327.694537 664.8525 Protein PRRC2C OS=Homo sapiens OX=9606 GN=PRRC2C PE=1 SV=4 8.5 3613.9 - 925835 - - - 3.1506 - 2.342 0.483 - 328.7 1 2 0 0.0042 11 0 0 0 9.82E+06 1.11E+07 - - - 4.9093 0.9991 221125_WJC_METTL3_EV_vs_WT_F01.19013.19013.2 0.0156 20-Jul K.ELFPIQMEGVK[136.11].L "sp|O96008|TOM40_HUMAN,tr|K7EJ57|K7EJ57_HUMAN" 2 1297.6832 1.18 6598 19013 2 1297.684136 649.8489 Mitochondrial import receptor subunit TOM40 homolog OS=Homo sapiens OX=9606 GN=TOMM40 PE=1 SV=1 4.53 3614.1 - 517822 - - - 0.7521 - 1.526 0.33 - 130.1 1 2 0 0.001 11 0 0 0 2.76E+07 2.33E+07 - - - 2.6214 0.7817 221125_WJC_METTL3_EV_vs_WT_F01.19017.19017.2 7.88 14-Jul E.AVAGAFSR[166.11].C sp|Q96NM4|TOX2_HUMAN 1 787.4216 0 6602 19017 2 787.421417 394.7181 TOX high mobility group box family member 2 OS=Homo sapiens OX=9606 GN=TOX2 PE=1 SV=2 9.79 3614.6 - 246719 - - - -0.2413 - 1.614 0.109 - 127.6 2 1 0 -0.0002 8 0 0 0 4.20E+04 2.00E+07 - - - 1.1553 0.9998 221125_WJC_METTL3_EV_vs_WT_F01.19021.19021.2 2.31E-05 18-Sep R.SIPMTVDFIR[166.11].L sp|P00492|HPRT_HUMAN 1 1187.6248 0.69 6604 19021 2 1187.625477 594.8197 Hypoxanthine-guanine phosphoribosyltransferase OS=Homo sapiens OX=9606 GN=HPRT1 PE=1 SV=2 5.55 3615.1 - 1.03E+06 - - - 0.57 - 1.988 0.489 - 304.6 1 2 0 0.0007 10 0 0 0 2.00E+07 2.91E+07 - - - 4.5705 0.997 221125_WJC_METTL3_EV_vs_WT_F01.19022.19022.2 0.00362 14-Sep K.SLLIGVFK[136.11].H "sp|Q9P2D1|CHD7_HUMAN,sp|Q9HCK8|CHD8_HUMAN,sp|Q3L8U1|CHD9_HUMAN,sp|Q8TD26|CHD6_HUMAN,tr|H3BTW3|H3BTW3_HUMAN,tr|H7C294|H7C294_HUMAN,tr|A0A087WU44|A0A087WU44_HUMAN,tr|A0A2R8Y840|A0A2R8Y840_HUMAN,tr|H0YJG4|H0YJG4_HUMAN" 9 883.5622 1.25 6605 19022 2 883.562456 442.7884 Chromodomain-helicase-DNA-binding protein 7 OS=Homo sapiens OX=9606 GN=CHD7 PE=1 SV=3 8.47 3615.2 - 1.02E+06 - - - 0.2445 - 1.515 0.163 - 279.8 1 2 0 0.0002 8 0 0 0 3.31E+07 2.65E+07 - - - 1.4977 0.9966 221125_WJC_METTL3_EV_vs_WT_F01.19024.19024.2 0.0113 14-Aug K.SLLIGVFK.H "sp|Q9P2D1|CHD7_HUMAN,sp|Q9HCK8|CHD8_HUMAN,sp|Q3L8U1|CHD9_HUMAN,sp|Q8TD26|CHD6_HUMAN,tr|H3BTW3|H3BTW3_HUMAN,tr|H7C294|H7C294_HUMAN,tr|A0A087WU44|A0A087WU44_HUMAN,tr|A0A2R8Y840|A0A2R8Y840_HUMAN,tr|H0YJG4|H0YJG4_HUMAN" 9 875.548 1.25 6607 19024 2 875.54867 438.7813 Chromodomain-helicase-DNA-binding protein 7 OS=Homo sapiens OX=9606 GN=CHD7 PE=1 SV=3 8.47 3615.4 - 1.04E+06 - - - 0.7195 - 1.516 0.163 - 221 1 2 0 0.0006 8 0 0 0 3.31E+07 2.65E+07 - - - 1.4996 0.9995 221125_WJC_METTL3_EV_vs_WT_F01.19031.19031.2 0.000675 14-Aug K.LVYVDLLR.E "sp|Q6W2J9|BCOR_HUMAN,tr|H7BZ37|H7BZ37_HUMAN,tr|A1A564|A1A564_HUMAN,tr|H7C2V9|H7C2V9_HUMAN,tr|H7BYY2|H7BYY2_HUMAN,tr|H7C231|H7C231_HUMAN" 6 989.591 1.5 6612 19031 2 989.591986 495.8028 BCL-6 corepressor OS=Homo sapiens OX=9606 GN=BCOR PE=1 SV=1 5.84 3616.4 - 852391 - - - 1.0297 - 1.592 0.384 - 248 1 2 0 0.001 8 0 0 0 5.78E+07 3.85E+07 - - - 3.2793 0.995 221125_WJC_METTL3_EV_vs_WT_F01.19035.19035.2 0.0176 20-Aug K.LPDTTSIFALK[136.11].E "sp|Q00536|CDK16_HUMAN,tr|H0YC60|H0YC60_HUMAN,tr|H0YC36|H0YC36_HUMAN,tr|H0YAZ9|H0YAZ9_HUMAN,tr|A0A087WZU2|A0A087WZU2_HUMAN" 5 1212.6845 0.08 6616 19035 2 1212.687447 607.3495 Cyclin-dependent kinase 16 OS=Homo sapiens OX=9606 GN=CDK16 PE=1 SV=1 5.84 3616.8 - 215800 - - - 2.3972 - 1.467 0.252 - 118.8 1 2 0 0.0029 11 0 0 0 1.74E+06 2.22E+07 - - - 1.9381 0.9999 221125_WJC_METTL3_EV_vs_WT_F01.19039.19039.2 0.00233 13/20 R.TSLALDESLFR[166.11].G "sp|Q86U42|PABP2_HUMAN,tr|B4DEH8|B4DEH8_HUMAN,tr|G3V4T2|G3V4T2_HUMAN,tr|H0YJH9|H0YJH9_HUMAN,tr|A0A7I2V383|A0A7I2V383_HUMAN" 5 1260.6589 1.63 6619 19039 2 1260.659884 631.3367 Polyadenylate-binding protein 2 OS=Homo sapiens OX=9606 GN=PABPN1 PE=1 SV=3 4.37 3617.3 - 1.49E+06 - - - 0.7512 - 2.833 0.427 - 975.4 1 2 0 0.0009 11 0 0 0 8.66E+07 5.32E+07 - - - 5.0116 0.9997 221125_WJC_METTL3_EV_vs_WT_F01.19045.19045.2 0.000281 16-Nov K.ISVNDFIIK[136.11].A "sp|P10515|ODP2_HUMAN,tr|A0A7P0TBE2|A0A7P0TBE2_HUMAN,tr|A0A7P0Z4G4|A0A7P0Z4G4_HUMAN,tr|A0A7P0TAX2|A0A7P0TAX2_HUMAN,tr|A0A7P0TBK2|A0A7P0TBK2_HUMAN,tr|E9PEJ4|E9PEJ4_HUMAN,tr|A0A7P0TAG1|A0A7P0TAG1_HUMAN,tr|A0A7P0TA47|A0A7P0TA47_HUMAN,tr|A0A7P0T997|A0A7P0T997_HUMAN,tr|H0YDD4|H0YDD4_HUMAN" 10 1055.6106 0.84 6624 19045 2 1055.612073 528.8126 "Dihydrolipoyllysine-residue acetyltransferase component of pyruvate dehydrogenase complex, mitochondrial OS=Homo sapiens OX=9606 GN=DLAT PE=1 SV=3" 5.84 3617.9 - 580097 - - - 1.3509 - 2.145 0.414 - 231.9 1 2 0 0.0014 9 0 0 0 7.40E+06 8.86E+06 - - - 4.3062 0.9997 221125_WJC_METTL3_EV_vs_WT_F01.19046.19046.2 0.00623 24-Oct R.IITLTGPTNAIFK[136.11].A sp|Q15365|PCBP1_HUMAN 1 1395.8217 0.84 6625 19046 2 1395.823995 698.9181 Poly(rC)-binding protein 1 OS=Homo sapiens OX=9606 GN=PCBP1 PE=1 SV=2 8.75 3618 - 487112 - - - 1.6428 - 2.14 0.431 - 263.8 1 2 0 0.0023 13 0 0 0 2.78E+08 3.33E+08 - - - 4.1763 0.9992 221125_WJC_METTL3_EV_vs_WT_F01.19047.19047.2 0.00114 24-Nov R.IITLTGPTNAIFK.A sp|Q15365|PCBP1_HUMAN 1 1387.8075 0.84 6626 19047 2 1387.80442 694.911 Poly(rC)-binding protein 1 OS=Homo sapiens OX=9606 GN=PCBP1 PE=1 SV=2 8.75 3618.1 - 425390 - - - -2.2208 - 1.976 0.363 - 296.5 1 2 0 -0.0031 13 0 0 0 2.78E+08 3.33E+08 - - - 3.4691 0.8631 221125_WJC_METTL3_EV_vs_WT_F01.19050.19050.2 0.000534 18-Aug K.ELPEYYELIR[166.11].K "sp|P51531|SMCA2_HUMAN,sp|P51532|SMCA4_HUMAN,tr|A0A2R8Y5K3|A0A2R8Y5K3_HUMAN,tr|B1ALF6|B1ALF6_HUMAN,tr|A0A2R8Y7S2|A0A2R8Y7S2_HUMAN,tr|A0A0U1RQX3|A0A0U1RQX3_HUMAN,tr|A0A0A0MSS5|A0A0A0MSS5_HUMAN,tr|A0A2R8Y7F3|A0A2R8Y7F3_HUMAN,tr|A0A2R8YGG3|A0A2R8YGG3_HUMAN,tr|A0A1W2PS06|A0A1W2PS06_HUMAN,tr|A0A2R8Y523|A0A2R8Y523_HUMAN,tr|A0A2R8Y6V2|A0A2R8Y6V2_HUMAN,tr|A0A0U1RRG6|A0A0U1RRG6_HUMAN,tr|Q9HBD4|Q9HBD4_HUMAN,tr|A0A0U1RRD6|A0A0U1RRD6_HUMAN,tr|K7EQF0|K7EQF0_HUMAN,tr|A0A0U1RR26|A0A0U1RR26_HUMAN,tr|F6T8Q0|F6T8Q0_HUMAN,tr|F6UH26|F6UH26_HUMAN,tr|A0A0U1RRF8|A0A0U1RRF8_HUMAN,tr|A0A0U1RR83|A0A0U1RR83_HUMAN,tr|B1ALG2|B1ALG2_HUMAN,tr|A0A2R8Y440|A0A2R8Y440_HUMAN,tr|A0A0U1RQU0|A0A0U1RQU0_HUMAN,tr|F6VDE0|F6VDE0_HUMAN,tr|A0A2R8YFK5|A0A2R8YFK5_HUMAN,tr|A0A0U1RRN2|A0A0U1RRN2_HUMAN,tr|A0A2R8Y7Y7|A0A2R8Y7Y7_HUMAN,tr|A0A2R8YF58|A0A2R8YF58_HUMAN,tr|A0A2R8Y526|A0A2R8Y526_HUMAN,tr|K7EP28|K7EP28_HUMAN,tr|A0A2R8YG32|A0A2R8YG32_HUMAN,tr|F6XE55|F6XE55_HUMAN,tr|B4DNT1|B4DNT1_HUMAN,tr|A0A2R8Y6N0|A0A2R8Y6N0_HUMAN,tr|A0A2R8YF80|A0A2R8YF80_HUMAN,tr|A0A0U1RRF5|A0A0U1RRF5_HUMAN,tr|A0A2R8Y4P4|A0A2R8Y4P4_HUMAN,tr|A0A0U1RQW7|A0A0U1RQW7_HUMAN,tr|A0A0U1RR09|A0A0U1RR09_HUMAN,tr|B1ALG1|B1ALG1_HUMAN" 41 1333.6793 0.17 6629 19050 2 1334.677575 667.8469 Probable global transcription activator SNF2L2 OS=Homo sapiens OX=9606 GN=SMARCA2 PE=1 SV=2 4.25 3618.5 - 285473 - - - 748.4835 - 1.779 0.373 - 285.4 1 2 0 0.9982 10 0 0 0 2.56E+06 1.53E+07 - - - 3.0905 0.9908 221125_WJC_METTL3_EV_vs_WT_F01.19051.19051.2 0.744 14-May K.DDIPVFLR[166.11].H "sp|Q9UBB4|ATX10_HUMAN,tr|B1AHE4|B1AHE4_HUMAN,tr|A0A1W2PQD2|A0A1W2PQD2_HUMAN" 3 983.5316 0.84 6630 19051 2 983.533087 492.7731 Ataxin-10 OS=Homo sapiens OX=9606 GN=ATXN10 PE=1 SV=1 4.21 3618.7 - 265336 - - - 1.5607 - 1.24 0.206 - 58.9 2 2 0 0.0015 8 0 0 0 3.55E+06 4.21E+06 - - - 1.0763 0.9995 221125_WJC_METTL3_EV_vs_WT_F01.19057.19057.2 0.00151 22-Sep K.TPLPPELADVQA.- "sp|Q9Y5V0|ZN706_HUMAN,tr|H0YC70|H0YC70_HUMAN" 2 1249.6554 - 6634 19057 2 1249.657058 625.835 Zinc finger protein 706 OS=Homo sapiens OX=9606 GN=ZNF706 PE=1 SV=1 3.67 3619.5 - 3.29E+06 - - - 1.3124 - 1.721 0.423 - 241.5 1 2 0 0.0016 12 0 0 0 - - - - - 3.5932 0.9997 221125_WJC_METTL3_EV_vs_WT_F01.19058.19058.2 0.000883 18-Oct K.QVSDLISVLR.E "sp|P17844|DDX5_HUMAN,tr|J3KTA4|J3KTA4_HUMAN,tr|A0A0G2JLI4|A0A0G2JLI4_HUMAN" 3 1128.6503 0.2 6635 19058 2 1128.651744 565.3324 Probable ATP-dependent RNA helicase DDX5 OS=Homo sapiens OX=9606 GN=DDX5 PE=1 SV=1 5.84 3619.5 - 1.34E+06 - - - 1.3033 - 1.808 0.494 - 364.7 1 2 0 0.0015 10 0 0 0 1.35E+07 6.83E+07 - - - 4.3423 0.9929 221125_WJC_METTL3_EV_vs_WT_F01.19059.19059.2 0.54 14-Jun R.ELLIQFYK.S "sp|Q9UKV8|AGO2_HUMAN,sp|Q9UL18|AGO1_HUMAN,sp|Q9H9G7|AGO3_HUMAN,sp|Q9HCK5|AGO4_HUMAN,tr|A0A6I8PTZ8|A0A6I8PTZ8_HUMAN,tr|Q5TA58|Q5TA58_HUMAN" 6 1052.5906 1.11 6636 19059 2 1052.593068 527.3026 Protein argonaute-2 OS=Homo sapiens OX=9606 GN=AGO2 PE=1 SV=3 6.1 3619.6 - 1.09E+06 - - - 2.3133 - 1.467 0.211 - 102.8 2 2 0 0.0024 8 0 0 0 1.34E+07 1.21E+07 - - - 1.62 0.9313 221125_WJC_METTL3_EV_vs_WT_F01.19060.19060.2 0.0598 14-Jun K.NALESYAF.N "sp|P0DMV8|HS71A_HUMAN,sp|P34931|HS71L_HUMAN,sp|P0DMV9|HS71B_HUMAN,tr|Q53FA3|Q53FA3_HUMAN,tr|V9GZ37|V9GZ37_HUMAN,tr|A0A0G2JIW1|A0A0G2JIW1_HUMAN" 6 913.4181 - 6637 19060 2 913.419274 457.7164 Heat shock 70 kDa protein 1A OS=Homo sapiens OX=9606 GN=HSPA1A PE=1 SV=1 4 3619.7 - 1.08E+06 - - - 1.2327 - 1.225 0.391 - 115.2 1 1 0 0.0011 8 0 0 0 - - - - - 2.5406 1 221125_WJC_METTL3_EV_vs_WT_F01.19062.19062.2 1.07E-06 15/24 V.ALVMLQEDELLSK.M sp|Q96A49|SYAP1_HUMAN 1 1487.7905 1.37 6639 19062 2 1487.792091 744.9025 Synapse-associated protein 1 OS=Homo sapiens OX=9606 GN=SYAP1 PE=1 SV=1 4.14 3619.9 - 756975 - - - 1.0479 - 3.073 0.53 - 811.7 1 1 0 0.0016 13 0 0 0 5.91E+07 4.32E+07 - - - 5.8364 0.9974 221125_WJC_METTL3_EV_vs_WT_F01.19063.19063.2 0.527 24-Oct K.LGLSLVVPGGGIK.K sp|Q99747|SNAG_HUMAN 1 1208.7493 1.64 6640 19063 2 1208.752202 605.3819 Gamma-soluble NSF attachment protein OS=Homo sapiens OX=9606 GN=NAPG PE=1 SV=1 8.75 3620.1 - 462685 - - - 2.4347 - 1.877 0.252 - 204.8 1 2 0 0.0029 13 0 0 0 8.77E+06 5.34E+06 - - - 2.5174 0.999 221125_WJC_METTL3_EV_vs_WT_F01.19064.19064.2 0.00573 18-Sep R.VIEQLLVGLK[136.11].D "sp|Q9BTW9|TBCD_HUMAN,tr|A0A804HJ32|A0A804HJ32_HUMAN,tr|A0A804HKT8|A0A804HKT8_HUMAN,tr|A0A804HHW7|A0A804HHW7_HUMAN,tr|A0A804HL21|A0A804HL21_HUMAN,tr|A0A804HKB9|A0A804HKB9_HUMAN,tr|A0A804HJY5|A0A804HJY5_HUMAN,tr|A0A804HI02|A0A804HI02_HUMAN,tr|A0A804HIU1|A0A804HIU1_HUMAN,tr|A0A804HJ57|A0A804HJ57_HUMAN,tr|A0A804HLF8|A0A804HLF8_HUMAN,tr|A0A804HL62|A0A804HL62_HUMAN,tr|A0A804HIC0|A0A804HIC0_HUMAN,tr|J3KR97|J3KR97_HUMAN,tr|A0A804HI57|A0A804HI57_HUMAN,tr|A0A804HIN6|A0A804HIN6_HUMAN,tr|A0A804HLI2|A0A804HLI2_HUMAN" 17 1118.7154 0.42 6641 19064 2 1118.716981 560.365 Tubulin-specific chaperone D OS=Homo sapiens OX=9606 GN=TBCD PE=1 SV=2 5.97 3620.2 - 427619 - - - 1.3721 - 1.558 0.343 - 151.4 1 2 0 0.0015 10 0 0 0 1.46E+06 3.50E+06 - - - 2.8116 0.9997 221125_WJC_METTL3_EV_vs_WT_F01.19066.19066.2 0.0234 24-Nov K.LGLSLVVPGGGIK[136.11].K sp|Q99747|SNAG_HUMAN 1 1216.7635 1.64 6643 19066 2 1216.763618 609.389 Gamma-soluble NSF attachment protein OS=Homo sapiens OX=9606 GN=NAPG PE=1 SV=1 8.75 3620.4 - 252829 - - - 0.1307 - 2.068 0.348 - 248 1 2 0 0.0002 13 0 0 0 8.77E+06 5.34E+06 - - - 3.4761 0.9997 221125_WJC_METTL3_EV_vs_WT_F01.19067.19067.2 7.46E-06 14/24 R.IPSPLGYAAIPIK[136.11].F sp|Q9Y3A4|RRP7A_HUMAN 1 1346.8053 1.31 6644 19067 2 1346.808332 674.4099 Ribosomal RNA-processing protein 7 homolog A OS=Homo sapiens OX=9606 GN=RRP7A PE=1 SV=2 8.59 3620.6 - 238329 - - - 2.2334 - 2.298 0.5 - 694.3 1 2 0 0.003 13 0 0 0 4.34E+07 3.31E+07 - - - 4.8685 0.9986 221125_WJC_METTL3_EV_vs_WT_F01.19069.19069.2 0.0964 16-Jul R.VVVLGLLPR.G "sp|Q15102|PA1B3_HUMAN,tr|M0R389|M0R389_HUMAN" 2 964.6433 0.97 6646 19069 2 964.644911 483.3289 Platelet-activating factor acetylhydrolase IB subunit alpha1 OS=Homo sapiens OX=9606 GN=PAFAH1B3 PE=1 SV=1 9.72 3620.8 - 196893 - - - 1.6317 - 1.645 0.294 - 145.1 1 2 0 0.0016 9 0 0 0 1.77E+06 1.82E+06 - - - 2.652 1 221125_WJC_METTL3_EV_vs_WT_F01.19070.19070.2 3.43E-06 20-Dec R.FFDEESYSLLR.K "sp|P51571|SSRD_HUMAN,tr|A6NLM8|A6NLM8_HUMAN" 2 1404.6561 2.18 6647 19070 2 1404.647334 703.3353 Translocon-associated protein subunit delta OS=Homo sapiens OX=9606 GN=SSR4 PE=1 SV=1 4.14 3621 - 190679 - - - -6.2734 - 2.494 0.618 - 367.1 1 2 0 -0.0088 11 0 0 0 1.38E+08 6.34E+07 - - - 6.0751 0.9959 221125_WJC_METTL3_EV_vs_WT_F01.19071.19071.2 0.127 28-Jul R.QLLAPGNSAGAFLIR[166.11].E sp|P07948|LYN_HUMAN 1 1536.8652 0.3 6648 19071 2 1536.866044 769.4399 Tyrosine-protein kinase Lyn OS=Homo sapiens OX=9606 GN=LYN PE=1 SV=3 9.75 3621.1 - 172936 - - - 0.5609 - 1.55 0.162 - 71.5 1 2 0 0.0009 15 0 0 0 2.11E+05 7.13E+05 - - - 1.3147 0.999 221125_WJC_METTL3_EV_vs_WT_F01.19075.19075.2 0.124 14-Aug R.LPLFGLGR[166.11].L "sp|P82930|RT34_HUMAN,tr|C9JJ19|C9JJ19_HUMAN" 2 881.5362 1.17 6650 19075 2 881.536671 441.7754 "28S ribosomal protein S34, mitochondrial OS=Homo sapiens OX=9606 GN=MRPS34 PE=1 SV=2" 9.75 3621.7 - 7.75E+06 - - - 0.4855 - 1.675 0.254 - 305.9 1 2 0 0.0004 8 0 0 0 1.14E+08 9.71E+07 - - - 2.4726 0.9943 221125_WJC_METTL3_EV_vs_WT_F01.19076.19076.2 0.508 14-Aug R.LPLFGLGR.L "sp|P82930|RT34_HUMAN,tr|C9JJ19|C9JJ19_HUMAN" 2 871.528 1.17 6651 19076 2 871.528395 436.7713 "28S ribosomal protein S34, mitochondrial OS=Homo sapiens OX=9606 GN=MRPS34 PE=1 SV=2" 9.75 3621.7 - 6.03E+06 - - - 0.4842 - 1.487 0.113 - 290.4 1 2 0 0.0004 8 0 0 0 1.14E+08 9.71E+07 - - - 1.0721 0.9995 221125_WJC_METTL3_EV_vs_WT_F01.19077.19077.2 0.0174 14-Jul K.LVYVDLLR[166.11].E "sp|Q6W2J9|BCOR_HUMAN,tr|H7BZ37|H7BZ37_HUMAN,tr|A1A564|A1A564_HUMAN,tr|H7C2V9|H7C2V9_HUMAN,tr|H7BYY2|H7BYY2_HUMAN,tr|H7C231|H7C231_HUMAN" 6 999.5992 1.51 6652 19077 2 999.599935 500.8069 BCL-6 corepressor OS=Homo sapiens OX=9606 GN=BCOR PE=1 SV=1 5.84 3621.7 - 5.16E+06 - - - 0.6983 - 1.563 0.377 - 233.2 1 2 0 0.0007 8 0 0 0 5.77E+07 3.83E+07 - - - 3.1722 0.9998 221125_WJC_METTL3_EV_vs_WT_F01.19078.19078.2 1.17E-05 22-Dec R.VFIGNLNTLVVK[136.11].K "sp|P0DMR1|HNRC4_HUMAN,sp|P07910|HNRPC_HUMAN,sp|O60812|HNRC1_HUMAN,sp|B2RXH8|HNRC2_HUMAN,sp|B7ZW38|HNRC3_HUMAN,tr|G3V251|G3V251_HUMAN,tr|B4DY08|B4DY08_HUMAN,tr|G3V575|G3V575_HUMAN,tr|B4DSU6|B4DSU6_HUMAN,tr|G3V3K6|G3V3K6_HUMAN,tr|B2R5W2|B2R5W2_HUMAN,tr|G3V4C1|G3V4C1_HUMAN,tr|A0A0G2JPF8|A0A0G2JPF8_HUMAN,tr|A0A0G2JNQ3|A0A0G2JNQ3_HUMAN,tr|G3V576|G3V576_HUMAN,tr|G3V5X6|G3V5X6_HUMAN,tr|G3V2H6|G3V2H6_HUMAN,tr|G3V4W0|G3V4W0_HUMAN,tr|G3V555|G3V555_HUMAN,tr|G3V4M8|G3V4M8_HUMAN,tr|G3V2Q1|G3V2Q1_HUMAN" 21 1323.8006 1.39 6653 19078 2 1323.801547 662.9076 Heterogeneous nuclear ribonucleoprotein C-like 4 OS=Homo sapiens OX=9606 GN=HNRNPCL4 PE=3 SV=1 8.72 3621.8 - 3.95E+06 - - - 0.7358 - 2.252 0.455 - 415.1 1 2 0 0.001 12 0 0 0 3.45E+09 2.48E+09 - - - 4.5374 0.9999 221125_WJC_METTL3_EV_vs_WT_F01.19079.19079.2 4.58E-06 22-Dec R.VFIGNLNTLVVK.K "sp|P0DMR1|HNRC4_HUMAN,sp|P07910|HNRPC_HUMAN,sp|O60812|HNRC1_HUMAN,sp|B2RXH8|HNRC2_HUMAN,sp|B7ZW38|HNRC3_HUMAN,tr|G3V251|G3V251_HUMAN,tr|B4DY08|B4DY08_HUMAN,tr|G3V575|G3V575_HUMAN,tr|B4DSU6|B4DSU6_HUMAN,tr|G3V3K6|G3V3K6_HUMAN,tr|B2R5W2|B2R5W2_HUMAN,tr|G3V4C1|G3V4C1_HUMAN,tr|A0A0G2JPF8|A0A0G2JPF8_HUMAN,tr|A0A0G2JNQ3|A0A0G2JNQ3_HUMAN,tr|G3V576|G3V576_HUMAN,tr|G3V5X6|G3V5X6_HUMAN,tr|G3V2H6|G3V2H6_HUMAN,tr|G3V4W0|G3V4W0_HUMAN,tr|G3V555|G3V555_HUMAN,tr|G3V4M8|G3V4M8_HUMAN,tr|G3V2Q1|G3V2Q1_HUMAN" 21 1315.7864 1.39 6654 19079 2 1315.788392 658.9005 Heterogeneous nuclear ribonucleoprotein C-like 4 OS=Homo sapiens OX=9606 GN=HNRNPCL4 PE=3 SV=1 8.72 3621.9 - 3.56E+06 - - - 1.5344 - 2.264 0.606 - 402.3 1 2 0 0.002 12 0 0 0 3.45E+09 2.48E+09 - - - 5.6663 0.9896 221125_WJC_METTL3_EV_vs_WT_F01.19081.19081.2 1.22E-05 13/24 V.ALVMLQEDELLSK[136.11].M sp|Q96A49|SYAP1_HUMAN 1 1495.8047 1.37 6656 19081 2 1495.806282 748.9096 Synapse-associated protein 1 OS=Homo sapiens OX=9606 GN=SYAP1 PE=1 SV=1 4.14 3621.9 - 2.56E+06 - - - 1.0362 - 2.814 0.41 - 548.8 1 1 0 0.0015 13 0 0 0 5.91E+07 4.32E+07 - - - 4.7241 0.9607 221125_WJC_METTL3_EV_vs_WT_F01.19082.19082.2 0.0117 20-Aug R.VPTANVSVVDL.T "sp|P04406|G3P_HUMAN,tr|E7EUT5|E7EUT5_HUMAN" 2 1112.6077 - 6657 19082 2 1112.608117 557.3111 Glyceraldehyde-3-phosphate dehydrogenase OS=Homo sapiens OX=9606 GN=GAPDH PE=1 SV=3 3.8 3622 - 2.32E+06 - - - 0.3388 - 1.515 0.352 - 166 1 1 0 0.0004 11 0 0 0 - - - - - 2.7646 0.9999 221125_WJC_METTL3_EV_vs_WT_F01.19084.19084.2 0.000586 16-Sep K.LPFPIIDDR.N sp|P30041|PRDX6_HUMAN 1 1084.5917 1 6659 19084 2 1084.592072 543.3031 Peroxiredoxin-6 OS=Homo sapiens OX=9606 GN=PRDX6 PE=1 SV=3 4.21 3622.1 - 1.86E+06 - - - 0.3467 - 2.116 0.466 - 398.8 1 2 0 0.0004 9 0 0 0 1.65E+08 1.65E+08 - - - 4.6512 0.9172 221125_WJC_METTL3_EV_vs_WT_F01.19085.19085.2 0.0373 18-Jul R.TAAENDFVTL.K sp|P35908|K22E_HUMAN 1 1079.5135 - 6660 19085 2 1079.514121 540.764 "Keratin, type II cytoskeletal 2 epidermal OS=Homo sapiens OX=9606 GN=KRT2 PE=1 SV=2" 3.67 3622.2 - 1.84E+06 - - - 0.5706 - 1.182 0.353 - 130.9 1 1 0 0.0006 10 0 0 0 - - - - - 2.1148 0.9998 221125_WJC_METTL3_EV_vs_WT_F01.19086.19086.2 0.000211 20-Nov R.FFDEESYSLLR[166.11].K "sp|P51571|SSRD_HUMAN,tr|A6NLM8|A6NLM8_HUMAN" 2 1414.6644 2.18 6661 19086 2 1414.666245 708.3395 Translocon-associated protein subunit delta OS=Homo sapiens OX=9606 GN=SSR4 PE=1 SV=1 4.14 3622.3 - 1.83E+06 - - - 1.2929 - 2.264 0.538 - 293.2 1 2 0 0.0018 11 0 0 0 1.38E+08 6.34E+07 - - - 5.2246 0.9996 221125_WJC_METTL3_EV_vs_WT_F01.19087.19087.2 0.00184 16-Oct K.IPSVLFLGK.L sp|Q8IW75|SPA12_HUMAN 1 972.6008 999 6662 19087 2 972.601363 487.3077 Serpin A12 OS=Homo sapiens OX=9606 GN=SERPINA12 PE=1 SV=1 8.75 3622.4 - 1.22E+06 - - - 0.5747 - 1.699 0.369 - 269.7 1 2 0 0.0006 9 0 0 0 9.80E+06 0.00E+00 - - - 3.2997 0.9997 221125_WJC_METTL3_EV_vs_WT_F01.19101.19101.2 0.000185 20-Nov R.LLGLGVTDFSR[166.11].A "sp|Q7Z406|MYH14_HUMAN,tr|M0QY43|M0QY43_HUMAN" 2 1186.6585 0.97 6675 19101 2 1186.660552 594.3365 Myosin-14 OS=Homo sapiens OX=9606 GN=MYH14 PE=1 SV=2 5.84 3623.7 - 1.30E+06 - - - 1.693 - 2.344 0.395 - 395.7 1 2 0 0.002 11 0 0 0 1.11E+07 1.14E+07 - - - 4.2623 0.9999 221125_WJC_METTL3_EV_vs_WT_F01.19104.19104.2 4.42E-07 24-Nov K.AFYGDTLVTGFAR[166.11].L "sp|Q9HCC0|MCCB_HUMAN,tr|A0A804HK37|A0A804HK37_HUMAN,tr|A0A804HJ24|A0A804HJ24_HUMAN,tr|A0A804HL02|A0A804HL02_HUMAN,tr|A0A804HKE8|A0A804HKE8_HUMAN,tr|A0A804HLJ9|A0A804HLJ9_HUMAN,tr|A0A804HJL2|A0A804HJL2_HUMAN,tr|A0A804HJ31|A0A804HJ31_HUMAN" 8 1426.712 0.09 6678 19104 2 1426.710098 714.3633 "Methylcrotonoyl-CoA carboxylase beta chain, mitochondrial OS=Homo sapiens OX=9606 GN=MCCC2 PE=1 SV=1" 5.88 3624.1 - 630835 - - - -1.3577 - 2.206 0.593 - 362.4 1 2 0 -0.0019 13 0 0 0 1.47E+06 1.65E+07 - - - 5.4509 1 221125_WJC_METTL3_EV_vs_WT_F01.19109.19109.2 1.02E-06 16/28 K.FIIENTDLAVANSIR[166.11].R "sp|P19387|RPB3_HUMAN,tr|H3BRR2|H3BRR2_HUMAN" 2 1684.9024 1.87 6683 19109 2 1684.897272 843.4585 DNA-directed RNA polymerase II subunit RPB3 OS=Homo sapiens OX=9606 GN=POLR2C PE=1 SV=2 4.37 3624.8 - 298563 - - - -3.0168 - 2.95 0.59 - 747.8 1 2 0 -0.0051 15 0 0 0 2.12E+06 1.13E+06 - - - 6.0568 0.8129 221125_WJC_METTL3_EV_vs_WT_F01.19112.19112.2 0.323 12-Jun L.PLFGLGR.L "sp|P82930|RT34_HUMAN,tr|C9JJ19|C9JJ19_HUMAN" 2 758.4439 0.69 6686 19112 2 758.44297 380.2292 "28S ribosomal protein S34, mitochondrial OS=Homo sapiens OX=9606 GN=MRPS34 PE=1 SV=2" 10.18 3625.2 - 152672 - - - -1.2381 - 1.377 0.198 - 120.6 1 1 0 -0.0009 7 0 0 0 1.41E+06 2.04E+06 - - - 1.5168 0.9998 221125_WJC_METTL3_EV_vs_WT_F01.19116.19116.2 0.00199 16-Sep K.LPFPIIDDR[166.11].N sp|P30041|PRDX6_HUMAN 1 1094.6 1 6688 19116 2 1094.598614 548.3073 Peroxiredoxin-6 OS=Homo sapiens OX=9606 GN=PRDX6 PE=1 SV=3 4.21 3625.7 - 1.14E+07 - - - -1.2352 - 2.066 0.486 - 434.4 1 2 0 -0.0014 9 0 0 0 1.65E+08 1.65E+08 - - - 4.7294 0.9813 221125_WJC_METTL3_EV_vs_WT_F01.19120.19120.2 1.15 16-Jun R.ALLNVSISR[166.11].E sp|Q9UHP6|RSP14_HUMAN 1 981.5847 0.01 6692 19120 2 981.584793 491.7996 Radial spoke head 14 homolog OS=Homo sapiens OX=9606 GN=RSPH14 PE=1 SV=1 9.79 3626.1 - 713458 - - - 0.1457 - 1.089 0.125 - 101.8 1 2 0 0.0001 9 0 0 0 1.07E+05 1.83E+07 - - - 0.2109 0.9998 221125_WJC_METTL3_EV_vs_WT_F01.19121.19121.2 3.93E-05 20-Oct K.ELLDTELDLYK.K "sp|Q5T8P6|RBM26_HUMAN,tr|A0A087X0H9|A0A087X0H9_HUMAN" 2 1350.6919 0.89 6693 19121 2 1350.692457 676.3532 RNA-binding protein 26 OS=Homo sapiens OX=9606 GN=RBM26 PE=1 SV=3 3.92 3626.2 - 663035 - - - 0.4398 - 2.114 0.468 - 299.8 1 2 0 0.0006 11 0 0 0 6.65E+06 7.48E+06 - - - 4.5226 0.9998 221125_WJC_METTL3_EV_vs_WT_F01.19132.19132.2 0.000506 16-Nov K.TLEEILLER[166.11].A "sp|O75152|ZC11A_HUMAN,tr|E9PBY7|E9PBY7_HUMAN,tr|E9PQ61|E9PQ61_HUMAN" 3 1124.6317 2.27 6703 19132 2 1124.630218 563.3231 Zinc finger CCCH domain-containing protein 11A OS=Homo sapiens OX=9606 GN=ZC3H11A PE=1 SV=3 4.25 3627.5 - 1.86E+06 - - - -1.2822 - 2.338 0.465 - 408.4 1 2 0 -0.0014 9 0 0 0 8.14E+07 3.58E+07 - - - 4.9321 0.9996 221125_WJC_METTL3_EV_vs_WT_F01.19135.19135.2 0.00228 14-Aug K.YWYLGPLK[136.11].L "sp|Q53H12|AGK_HUMAN,tr|E9PC15|E9PC15_HUMAN,tr|A0A0G2JLD0|A0A0G2JLD0_HUMAN,tr|E9PG39|E9PG39_HUMAN,tr|A0A3B3ITD0|A0A3B3ITD0_HUMAN,tr|A0A3B3ISY9|A0A3B3ISY9_HUMAN,tr|A0A0G2JLG5|A0A0G2JLG5_HUMAN,tr|A0A3B3ISZ0|A0A3B3ISZ0_HUMAN" 8 1046.5681 1.34 6706 19135 2 1046.568207 524.2913 "Acylglycerol kinase, mitochondrial OS=Homo sapiens OX=9606 GN=AGK PE=1 SV=2" 8.5 3627.7 - 1.23E+06 - - - 0.1462 - 1.496 0.415 - 231.5 1 2 0 0.0002 8 0 0 0 2.03E+07 1.51E+07 - - - 3.321 0.9515 221125_WJC_METTL3_EV_vs_WT_F01.19136.19136.2 1.79 12-Jun R.AFLPLLK[136.11].A "sp|Q14690|RRP5_HUMAN,tr|A0A3B3IUD7|A0A3B3IUD7_HUMAN" 2 808.5302 0.72 6707 19136 2 808.528734 405.2724 Protein RRP5 homolog OS=Homo sapiens OX=9606 GN=PDCD11 PE=1 SV=3 8.8 3627.8 - 724745 - - - -1.8268 - 1.122 0.079 - 174.6 1 2 0 -0.0015 7 0 0 0 1.54E+07 2.14E+07 - - - -0.0112 0.9987 221125_WJC_METTL3_EV_vs_WT_F01.19141.19141.3 0.00722 Aug-44 R.VFIGNLNTLVVK.K "sp|P0DMR1|HNRC4_HUMAN,sp|P07910|HNRPC_HUMAN,sp|O60812|HNRC1_HUMAN,sp|B2RXH8|HNRC2_HUMAN,sp|B7ZW38|HNRC3_HUMAN,tr|G3V251|G3V251_HUMAN,tr|B4DY08|B4DY08_HUMAN,tr|G3V575|G3V575_HUMAN,tr|B4DSU6|B4DSU6_HUMAN,tr|G3V3K6|G3V3K6_HUMAN,tr|B2R5W2|B2R5W2_HUMAN,tr|G3V4C1|G3V4C1_HUMAN,tr|A0A0G2JPF8|A0A0G2JPF8_HUMAN,tr|A0A0G2JNQ3|A0A0G2JNQ3_HUMAN,tr|G3V576|G3V576_HUMAN,tr|G3V5X6|G3V5X6_HUMAN,tr|G3V2H6|G3V2H6_HUMAN,tr|G3V4W0|G3V4W0_HUMAN,tr|G3V555|G3V555_HUMAN,tr|G3V4M8|G3V4M8_HUMAN,tr|G3V2Q1|G3V2Q1_HUMAN" 21 1315.7864 0.87 6710 19141 3 1315.783814 439.6027 Heterogeneous nuclear ribonucleoprotein C-like 4 OS=Homo sapiens OX=9606 GN=HNRNPCL4 PE=3 SV=1 8.72 3628.5 - 1.02E+07 - - - -1.9448 - 1.657 0.32 - 73.4 1 2 0 -0.0026 12 0 0 0 8.56E+07 9.88E+07 - - - 3.5068 0.9491 221125_WJC_METTL3_EV_vs_WT_F01.19142.19142.2 9.35E-07 24-Oct R.SYEAVAAAAASVY.N sp|Q9BWF3|RBM4_HUMAN 1 1271.6034 - 6711 19142 2 1271.598778 636.809 RNA-binding protein 4 OS=Homo sapiens OX=9606 GN=RBM4 PE=1 SV=1 4 3628.6 - 1.10E+06 - - - -3.6214 - 2.142 0.512 - 298.1 1 1 0 -0.0046 13 0 0 0 - - - - - 4.7762 0.8855 221125_WJC_METTL3_EV_vs_WT_F01.19143.19143.2 2.03 12-May R.AFLPLLK.A "sp|Q14690|RRP5_HUMAN,tr|A0A3B3IUD7|A0A3B3IUD7_HUMAN" 2 800.516 0.72 6712 19143 2 800.513656 401.2653 Protein RRP5 homolog OS=Homo sapiens OX=9606 GN=PDCD11 PE=1 SV=3 8.8 3628.8 - 781756 - - - -2.9419 - 1.113 0.072 - 117.2 1 2 0 -0.0024 7 0 0 0 1.54E+07 2.14E+07 - - - -0.0887 0.9948 221125_WJC_METTL3_EV_vs_WT_F01.19145.19145.2 0.265 14-Jun R.LWLLDDSK[136.11].T "sp|O43639|NCK2_HUMAN,sp|P16333|NCK1_HUMAN,tr|E7EPF5|E7EPF5_HUMAN,tr|E7ERP6|E7ERP6_HUMAN,tr|C9J0K5|C9J0K5_HUMAN,tr|C9K098|C9K098_HUMAN,tr|C9J869|C9J869_HUMAN,tr|C9JVV5|C9JVV5_HUMAN,tr|E9PEE2|E9PEE2_HUMAN,tr|H7C5C7|H7C5C7_HUMAN" 10 996.5371 0.82 6714 19145 2 996.536429 499.2758 Cytoplasmic protein NCK2 OS=Homo sapiens OX=9606 GN=NCK2 PE=1 SV=2 4.21 3629 - 486449 - - - -0.7205 - 1.491 0.12 - 99.6 1 2 0 -0.0007 8 0 0 0 3.33E+06 4.05E+06 - - - 1.1318 0.9998 221125_WJC_METTL3_EV_vs_WT_F01.19146.19146.2 0.00504 26-Dec K.VLELDPALAPVVSR.E "sp|O00170|AIP_HUMAN,tr|A0A804HKK3|A0A804HKK3_HUMAN,tr|A0A804HKL7|A0A804HKL7_HUMAN,tr|A0A804HJ46|A0A804HJ46_HUMAN,tr|E9PMH2|E9PMH2_HUMAN,tr|A0A804HKH9|A0A804HKH9_HUMAN" 6 1477.8504 1.87 6715 19146 2 1477.848366 739.9325 AH receptor-interacting protein OS=Homo sapiens OX=9606 GN=AIP PE=1 SV=2 4.37 3629.1 - 449137 - - - -1.3966 - 2.641 0.475 - 341.1 1 2 0 -0.0021 14 0 0 0 4.93E+07 2.64E+07 - - - 4.9858 0.9981 221125_WJC_METTL3_EV_vs_WT_F01.19151.19151.2 9.86E-05 13/20 K.VTGEVLDILTR[166.11].L "sp|O75955|FLOT1_HUMAN,tr|A0A140T9W4|A0A140T9W4_HUMAN,tr|A0A140T9R1|A0A140T9R1_HUMAN,tr|A0A140T974|A0A140T974_HUMAN" 4 1224.6953 1.62 6718 19151 2 1224.689286 613.3549 Flotillin-1 OS=Homo sapiens OX=9606 GN=FLOT1 PE=1 SV=3 4.37 3629.8 - 803243 - - - -4.9294 - 2.239 0.532 - 632.5 1 2 0 -0.006 11 0 0 0 1.75E+07 1.08E+07 - - - 5.149 0.9329 221125_WJC_METTL3_EV_vs_WT_F01.19158.19158.2 3.63 16-Jul K.QDVVLNYPM.- "sp|Q15029|U5S1_HUMAN,tr|K7EP67|K7EP67_HUMAN" 2 1077.5165 - 6723 19158 2 1077.5152 539.7655 116 kDa U5 small nuclear ribonucleoprotein component OS=Homo sapiens OX=9606 GN=EFTUD2 PE=1 SV=1 3.8 3630.7 - 2.11E+06 - - - -1.1898 - 0.96 0.083 - 73.5 1 2 0 -0.0013 9 0 0 0 - - - - - -0.4645 0.9999 221125_WJC_METTL3_EV_vs_WT_F01.19160.19160.2 0.000822 13/26 K.VLELDPALAPVVSR[166.11].E "sp|O00170|AIP_HUMAN,tr|A0A804HKK3|A0A804HKK3_HUMAN,tr|A0A804HKL7|A0A804HKL7_HUMAN,tr|A0A804HJ46|A0A804HJ46_HUMAN,tr|E9PMH2|E9PMH2_HUMAN,tr|A0A804HKH9|A0A804HKH9_HUMAN" 6 1487.8587 1.87 6725 19160 2 1487.85709 744.9366 AH receptor-interacting protein OS=Homo sapiens OX=9606 GN=AIP PE=1 SV=2 4.37 3631 - 1.51E+06 - - - -1.0821 - 2.642 0.525 - 446 1 2 0 -0.0016 14 0 0 0 4.93E+07 2.64E+07 - - - 5.3562 0.9978 221125_WJC_METTL3_EV_vs_WT_F01.19161.19161.2 0.00586 14-Aug R.EMVLEIIR.E "sp|Q96I24|FUBP3_HUMAN,sp|Q96AE4|FUBP1_HUMAN,tr|E9PEB5|E9PEB5_HUMAN" 3 1001.558 1.13 6726 19161 2 1001.555215 501.7863 Far upstream element-binding protein 3 OS=Homo sapiens OX=9606 GN=FUBP3 PE=1 SV=2 4.53 3631.1 - 1.16E+06 - - - -2.7337 - 1.863 0.264 - 314.2 1 2 0 -0.0027 8 0 0 0 4.27E+07 3.79E+07 - - - 2.8665 0.9988 221125_WJC_METTL3_EV_vs_WT_F01.19162.19162.2 0.00218 24-Aug R.LGFEGGQTPFYIR[166.11].L "sp|Q9P015|RM15_HUMAN,tr|E5RHF4|E5RHF4_HUMAN" 2 1493.7542 1.39 6727 19162 2 1493.751623 747.8844 "39S ribosomal protein L15, mitochondrial OS=Homo sapiens OX=9606 GN=MRPL15 PE=1 SV=1" 6 3631.2 - 642276 - - - -1.7486 - 1.677 0.323 - 147.7 1 2 0 -0.0026 13 0 0 0 7.63E+06 5.47E+06 - - - 2.7528 0.9995 221125_WJC_METTL3_EV_vs_WT_F01.19163.19163.2 0.0254 24-Nov R.IITLAGPTNAIFK[136.11].A "sp|Q15366|PCBP2_HUMAN,tr|F8W1G6|F8W1G6_HUMAN,tr|F8VZX2|F8VZX2_HUMAN,tr|F8W0G4|F8W0G4_HUMAN,tr|F8VXH9|F8VXH9_HUMAN,tr|H3BRU6|H3BRU6_HUMAN" 6 1365.8111 1.15 6728 19163 2 1365.808897 683.9128 Poly(rC)-binding protein 2 OS=Homo sapiens OX=9606 GN=PCBP2 PE=1 SV=1 8.75 3631.4 - 625485 - - - -1.6401 - 2.213 0.347 - 373.1 1 2 0 -0.0022 13 0 0 0 5.34E+08 4.65E+08 - - - 3.642 0.9686 221125_WJC_METTL3_EV_vs_WT_F01.19164.19164.2 3.55E-05 24-Oct K.EIAEAYLGYPVTN.A "sp|P0DMV8|HS71A_HUMAN,sp|P0DMV9|HS71B_HUMAN,tr|A0A0G2JIW1|A0A0G2JIW1_HUMAN" 3 1438.698 - 6729 19164 2 1438.69464 720.3563 Heat shock 70 kDa protein 1A OS=Homo sapiens OX=9606 GN=HSPA1A PE=1 SV=1 3.8 3631.5 - 529403 - - - -2.3431 - 1.788 0.485 - 271.4 1 1 0 -0.0034 13 0 0 0 - - - - - 4.1136 0.9997 221125_WJC_METTL3_EV_vs_WT_F01.19166.19166.2 6.28E-06 24-Dec R.IITLAGPTNAIFK.A "sp|Q15366|PCBP2_HUMAN,tr|F8W1G6|F8W1G6_HUMAN,tr|F8VZX2|F8VZX2_HUMAN,tr|F8W0G4|F8W0G4_HUMAN,tr|F8VXH9|F8VXH9_HUMAN,tr|H3BRU6|H3BRU6_HUMAN" 6 1357.7969 1.15 6731 19166 2 1357.794146 679.9057 Poly(rC)-binding protein 2 OS=Homo sapiens OX=9606 GN=PCBP2 PE=1 SV=1 8.75 3631.8 - 361744 - - - -2.0555 - 2.346 0.5 - 414.6 1 2 0 -0.0028 13 0 0 0 5.34E+08 4.65E+08 - - - 4.9216 0.9975 221125_WJC_METTL3_EV_vs_WT_F01.19171.19171.2 1.54 14-Aug R.EMVLEIIR[166.11].E "sp|Q96I24|FUBP3_HUMAN,sp|Q96AE4|FUBP1_HUMAN,tr|E9PEB5|E9PEB5_HUMAN" 3 1011.5662 1.13 6735 19171 2 1011.566243 506.7904 Far upstream element-binding protein 3 OS=Homo sapiens OX=9606 GN=FUBP3 PE=1 SV=2 4.53 3632.3 - 2.19E+06 - - - 0.0198 - 1.778 0.114 - 350 1 2 0 0 8 0 0 0 4.21E+07 3.73E+07 - - - 1.6186 0.9279 221125_WJC_METTL3_EV_vs_WT_F01.19174.19174.2 1.01 20-May K.GGFNRPLDFIA.- "sp|Q8WVK2|SNR27_HUMAN,tr|H0YBW5|H0YBW5_HUMAN" 2 1205.6193 1.04 6738 19174 2 1205.616717 603.8169 U4\U6.U5 small nuclear ribonucleoprotein 27 kDa protein OS=Homo sapiens OX=9606 GN=SNRNP27 PE=1 SV=1 5.84 3632.6 - 584785 - - - -2.1483 - 1.053 0.144 - 48.9 7 2 0 -0.0026 11 0 0 0 5.07E+06 4.86E+06 - - - -0.134 0.9974 221125_WJC_METTL3_EV_vs_WT_F01.19177.19177.2 0.552 18-Jul R.LLLQIPSTIR[166.11].S sp|Q16394|EXT1_HUMAN 1 1162.7313 1.38 6741 19177 2 1162.730805 582.3729 Exostosin-1 OS=Homo sapiens OX=9606 GN=EXT1 PE=1 SV=2 9.75 3633 - 291648 - - - -0.4378 - 1.558 0.178 - 116.1 1 2 0 -0.0005 10 0 0 0 4.58E+06 3.32E+06 - - - 1.5932 0.9997 221125_WJC_METTL3_EV_vs_WT_F01.19181.19181.2 0.0745 18-Nov K.AIDLFTDAIK.L "sp|P50502|F10A1_HUMAN,sp|Q8NFI4|F10A5_HUMAN,sp|Q8IZP2|ST134_HUMAN,tr|Q3KNR6|Q3KNR6_HUMAN,tr|H7C3I1|H7C3I1_HUMAN,tr|F6VDH7|F6VDH7_HUMAN" 6 1105.6019 1.1 6743 19181 2 1105.602574 553.8082 Hsc70-interacting protein OS=Homo sapiens OX=9606 GN=ST13 PE=1 SV=2 4.21 3633.6 - 6.86E+06 - - - 0.5861 - 2.149 0.36 - 314.1 2 2 0 0.0006 10 0 0 0 1.04E+08 9.46E+07 - - - 3.7006 0.9988 221125_WJC_METTL3_EV_vs_WT_F01.19182.19182.2 0.0498 16-Aug K.LSPEELLLR.W "sp|P13797|PLST_HUMAN,sp|Q14651|PLSI_HUMAN,sp|P13796|PLSL_HUMAN,tr|A0A0A0MSQ0|A0A0A0MSQ0_HUMAN,tr|C9JAM8|C9JAM8_HUMAN" 5 1068.6179 0.87 6744 19182 2 1068.616977 535.3162 Plastin-3 OS=Homo sapiens OX=9606 GN=PLS3 PE=1 SV=4 4.53 3633.7 - 1.08E+06 - - - -0.8731 - 1.589 0.268 - 156.8 1 2 0 -0.0009 9 0 0 0 2.63E+07 3.03E+07 - - - 2.3599 0.9993 221125_WJC_METTL3_EV_vs_WT_F01.19183.19183.2 0.0629 16-Oct K.NLLNLDVIK.K "sp|Q8NI36|WDR36_HUMAN,tr|A0A0A0MTB8|A0A0A0MTB8_HUMAN" 2 1040.623 1.04 6745 19183 2 1040.623093 521.3188 WD repeat-containing protein 36 OS=Homo sapiens OX=9606 GN=WDR36 PE=1 SV=1 5.84 3633.8 - 1.03E+06 - - - 0.0932 - 1.899 0.251 - 339 1 2 0 0.0001 9 0 0 0 4.03E+07 3.87E+07 - - - 2.7503 0.9933 221125_WJC_METTL3_EV_vs_WT_F01.19187.19187.2 0.00105 20-Sep K.FASVFGTMPLK.V "sp|Q93063|EXT2_HUMAN,tr|A0A804HKG2|A0A804HKG2_HUMAN,tr|A0A804HL74|A0A804HL74_HUMAN,tr|A0A804HHX4|A0A804HHX4_HUMAN" 4 1196.6264 0.44 6749 19187 2 1196.630995 599.3205 Exostosin-2 OS=Homo sapiens OX=9606 GN=EXT2 PE=1 SV=1 8.75 3634.3 - 485612 - - - 3.8675 - 1.725 0.282 - 157.9 1 2 0 0.0046 11 0 0 0 8.75E+06 2.01E+07 - - - 2.5974 0.9999 221125_WJC_METTL3_EV_vs_WT_F01.19188.19188.3 0.00313 16/52 K.VLELDPALAPVVSR[166.11].E "sp|O00170|AIP_HUMAN,tr|A0A804HKK3|A0A804HKK3_HUMAN,tr|A0A804HKL7|A0A804HKL7_HUMAN,tr|A0A804HJ46|A0A804HJ46_HUMAN,tr|E9PMH2|E9PMH2_HUMAN,tr|A0A804HKH9|A0A804HKH9_HUMAN" 6 1487.8587 1.8 6750 19188 3 1487.859668 496.9602 AH receptor-interacting protein OS=Homo sapiens OX=9606 GN=AIP PE=1 SV=2 4.37 3634.4 - 403617 - - - 0.6506 - 2.788 0.384 - 391.9 1 2 0 0.001 14 0 0 0 7.16E+06 3.98E+06 - - - 5.5458 0.9993 221125_WJC_METTL3_EV_vs_WT_F01.19191.19191.2 0.000184 22-Nov K.QVVPFVYQTIVK.D "sp|Q8IZH2|XRN1_HUMAN,tr|H7C5E4|H7C5E4_HUMAN" 2 1419.8126 1.29 6753 19191 2 1419.811596 710.9136 5'-3' exoribonuclease 1 OS=Homo sapiens OX=9606 GN=XRN1 PE=1 SV=1 8.59 3634.8 - 226859 - - - -0.6987 - 1.822 0.293 - 315 1 2 0 -0.001 12 0 0 0 2.94E+07 2.28E+07 - - - 2.7833 0.9183 221125_WJC_METTL3_EV_vs_WT_F01.19194.19194.2 1.75 22-Jun K.GLTPSQIGVILR.D "sp|P62277|RS13_HUMAN,tr|J3KMX5|J3KMX5_HUMAN" 2 1252.7503 17.36 6755 19194 2 1252.75336 627.3824 40S ribosomal protein S13 OS=Homo sapiens OX=9606 GN=RPS13 PE=1 SV=2 9.75 3635.2 - 1.24E+06 - - - 2.4251 - 1.184 0.09 - 77.8 3 2 0 0.003 12 0 0 0 8.65E+06 4.98E+05 - - - -0.0639 0.9999 221125_WJC_METTL3_EV_vs_WT_F01.19196.19196.2 0.00103 18-Dec R.LGLDDFESLK.V "sp|Q9Y2H1|ST38L_HUMAN,tr|F5GY51|F5GY51_HUMAN,tr|I3L0D0|I3L0D0_HUMAN,tr|F5H7Z3|F5H7Z3_HUMAN" 4 1135.5761 3.21 6756 19196 2 1135.576455 568.7953 Serine\threonine-protein kinase 38-like OS=Homo sapiens OX=9606 GN=STK38L PE=1 SV=3 4.03 3635.4 - 1.03E+07 - - - 0.3082 - 2.417 0.557 - 362.7 1 2 0 0.0003 10 0 0 0 2.87E+08 8.95E+07 - - - 5.6183 0.9993 221125_WJC_METTL3_EV_vs_WT_F01.19197.19197.2 0.0275 16-Sep K.NLLNLDVIK[136.11].K "sp|Q8NI36|WDR36_HUMAN,tr|A0A0A0MTB8|A0A0A0MTB8_HUMAN" 2 1048.6372 1.04 6757 19197 2 1048.63703 525.3259 WD repeat-containing protein 36 OS=Homo sapiens OX=9606 GN=WDR36 PE=1 SV=1 5.84 3635.5 - 3.07E+06 - - - -0.1583 - 1.878 0.251 - 268.7 1 2 0 -0.0002 9 0 0 0 4.03E+07 3.87E+07 - - - 2.7181 0.9999 221125_WJC_METTL3_EV_vs_WT_F01.19198.19198.2 0.000132 18-Oct R.LGLDDFESLK[136.11].V "sp|Q9Y2H1|ST38L_HUMAN,tr|F5GY51|F5GY51_HUMAN,tr|I3L0D0|I3L0D0_HUMAN,tr|F5H7Z3|F5H7Z3_HUMAN" 4 1143.5903 3.2 6758 19198 2 1143.590179 572.8024 Serine\threonine-protein kinase 38-like OS=Homo sapiens OX=9606 GN=STK38L PE=1 SV=3 4.03 3635.6 - 3.67E+06 - - - -0.1102 - 2.33 0.5 - 225.7 1 2 0 -0.0001 10 0 0 0 2.87E+08 8.98E+07 - - - 5.095 0.9999 221125_WJC_METTL3_EV_vs_WT_F01.19201.19201.2 2.05E-05 22-Dec K.QVVPFVYQTIVK[136.11].D "sp|Q8IZH2|XRN1_HUMAN,tr|H7C5E4|H7C5E4_HUMAN" 2 1427.8268 1.29 6761 19201 2 1427.826441 714.9207 5'-3' exoribonuclease 1 OS=Homo sapiens OX=9606 GN=XRN1 PE=1 SV=1 8.59 3635.9 - 538857 - - - -0.243 - 2.245 0.514 - 474.1 1 2 0 -0.0003 12 0 0 0 2.94E+07 2.28E+07 - - - 4.9651 0.9966 221125_WJC_METTL3_EV_vs_WT_F01.19202.19202.2 0.000423 16-Nov K.WQALLVQIR.K "sp|Q14204|DYHC1_HUMAN,tr|A0A7P0T8N2|A0A7P0T8N2_HUMAN,tr|A0A7P0T9C4|A0A7P0T9C4_HUMAN,tr|A0A7P0TBJ7|A0A7P0TBJ7_HUMAN,tr|A0A804HHY6|A0A804HHY6_HUMAN,tr|A0A7P0T9K2|A0A7P0T9K2_HUMAN,tr|A0A7P0TB64|A0A7P0TB64_HUMAN,tr|A0A2R8Y706|A0A2R8Y706_HUMAN,tr|A0A7P0T916|A0A7P0T916_HUMAN,tr|A0A7P0TB75|A0A7P0TB75_HUMAN,tr|A0A7P0T8W5|A0A7P0T8W5_HUMAN,tr|A0A7P0T9S3|A0A7P0T9S3_HUMAN,tr|A0A7P0TAF3|A0A7P0TAF3_HUMAN,tr|A0A7P0T9F1|A0A7P0T9F1_HUMAN,tr|A0A7P0TAW9|A0A7P0TAW9_HUMAN,tr|A0A2R8YGC7|A0A2R8YGC7_HUMAN,tr|A0A7P0TA13|A0A7P0TA13_HUMAN,tr|A0A7P0T934|A0A7P0T934_HUMAN,tr|A0A7P0TAV5|A0A7P0TAV5_HUMAN,tr|A0A7P0T9Y3|A0A7P0T9Y3_HUMAN,tr|A0A7P0T7V5|A0A7P0T7V5_HUMAN,tr|A0A7P0T9R4|A0A7P0T9R4_HUMAN,tr|A0A2R8Y5T0|A0A2R8Y5T0_HUMAN,tr|A0A7P0T990|A0A7P0T990_HUMAN,tr|A0A7P0T942|A0A7P0T942_HUMAN,tr|A0A2R8YFZ7|A0A2R8YFZ7_HUMAN,tr|A0A7P0T825|A0A7P0T825_HUMAN,tr|A0A2R8Y6H2|A0A2R8Y6H2_HUMAN,tr|A0A7P0TBC9|A0A7P0TBC9_HUMAN,tr|A0A7P0TAM4|A0A7P0TAM4_HUMAN" 30 1125.6659 0.46 6762 19202 2 1125.671419 563.8402 Cytoplasmic dynein 1 heavy chain 1 OS=Homo sapiens OX=9606 GN=DYNC1H1 PE=1 SV=5 9.75 3636 - 525168 - - - 4.9349 - 2.038 0.422 - 387.5 1 2 0 0.0056 9 0 0 0 3.63E+06 7.90E+06 - - - 4.2159 0.9999 221125_WJC_METTL3_EV_vs_WT_F01.19204.19204.2 6.00E-05 13/22 R.LLTWVIGTGSPR[166.11].L sp|Q92616|GCN1_HUMAN 1 1308.7429 0.81 6764 19204 2 1308.743257 655.3787 eIF-2-alpha kinase activator GCN1 OS=Homo sapiens OX=9606 GN=GCN1 PE=1 SV=6 9.75 3636.2 - 278093 - - - 0.2407 - 2.559 0.537 - 724.3 1 2 0 0.0003 12 0 0 0 8.00E+06 9.82E+06 - - - 5.4795 0.9998 221125_WJC_METTL3_EV_vs_WT_F01.19213.19213.2 0.000842 18-Oct K.AVQFFVQALR.M "sp|Q99615|DNJC7_HUMAN,tr|A0A6I8PRZ0|A0A6I8PRZ0_HUMAN,tr|A0A6I8PLE7|A0A6I8PLE7_HUMAN,tr|A0A6I8PR89|A0A6I8PR89_HUMAN,tr|A0A6I8PIK4|A0A6I8PIK4_HUMAN,tr|A0A6I8PUC2|A0A6I8PUC2_HUMAN,tr|A0A6I8PS32|A0A6I8PS32_HUMAN,tr|K7EPP7|K7EPP7_HUMAN,tr|A0A6I8PUD4|A0A6I8PUD4_HUMAN,tr|K7EIH8|K7EIH8_HUMAN,tr|K7ER44|K7ER44_HUMAN,tr|A0A6I8PU73|A0A6I8PU73_HUMAN,tr|K7EK03|K7EK03_HUMAN,tr|A0A6I8PU89|A0A6I8PU89_HUMAN" 14 1177.6608 0.65 6771 19213 2 1177.66037 589.8377 DnaJ homolog subfamily C member 7 OS=Homo sapiens OX=9606 GN=DNAJC7 PE=1 SV=2 9.79 3637.3 - 2.13E+06 - - - -0.3464 - 2.146 0.383 - 455.3 1 2 0 -0.0004 10 0 0 0 1.95E+07 2.98E+07 - - - 4.0012 0.9999 221125_WJC_METTL3_EV_vs_WT_F01.19215.19215.2 3.15E-06 20-Dec K.LWDLASGTLYK[136.11].E sp|O75529|TAF5L_HUMAN 1 1273.6798 0.95 6773 19215 2 1273.678277 637.8472 TAF5-like RNA polymerase II p300\CBP-associated factor-associated factor 65 kDa subunit 5L OS=Homo sapiens OX=9606 GN=TAF5L PE=1 SV=1 5.83 3637.4 - 1.65E+06 - - - -1.1871 - 2.393 0.545 - 473.4 1 2 0 -0.0015 11 0 0 0 1.60E+07 1.69E+07 - - - 5.4263 0.9998 221125_WJC_METTL3_EV_vs_WT_F01.19219.19219.2 2.18E-05 22-Oct K.VVLEGPAPWGFR[166.11].L "sp|Q9NR12|PDLI7_HUMAN,tr|D6RF83|D6RF83_HUMAN,tr|D6RAN1|D6RAN1_HUMAN,tr|H7BYK4|H7BYK4_HUMAN,tr|D6RH06|D6RH06_HUMAN" 5 1336.7167 0.43 6777 19219 2 1336.717191 669.3656 PDZ and LIM domain protein 7 OS=Homo sapiens OX=9606 GN=PDLIM7 PE=1 SV=1 5.97 3637.7 - 797528 - - - 0.3471 - 2.054 0.465 - 373.8 1 2 0 0.0005 12 0 0 0 4.64E+06 1.09E+07 - - - 4.3692 0.9994 221125_WJC_METTL3_EV_vs_WT_F01.19221.19221.2 0.00112 22-Nov R.LLTWVIGTGSPR.L sp|Q92616|GCN1_HUMAN 1 1298.7347 0.81 6779 19221 2 1298.736589 650.3746 eIF-2-alpha kinase activator GCN1 OS=Homo sapiens OX=9606 GN=GCN1 PE=1 SV=6 9.75 3637.9 - 587405 - - - 1.4761 - 2.038 0.331 - 495.9 1 2 0 0.0019 12 0 0 0 8.00E+06 9.82E+06 - - - 3.3585 0.9994 221125_WJC_METTL3_EV_vs_WT_F01.19223.19223.2 0.0741 16-Sep R.AELMQALWR[166.11].T "sp|Q9Y4A5|TRRAP_HUMAN,tr|H0Y4W2|H0Y4W2_HUMAN,tr|F2Z2U4|F2Z2U4_HUMAN" 3 1126.5833 1.29 6781 19223 2 1126.582719 564.2989 Transformation\transcription domain-associated protein OS=Homo sapiens OX=9606 GN=TRRAP PE=1 SV=3 6.05 3638.2 - 527533 - - - -0.4891 - 1.933 0.255 - 263.7 1 2 0 -0.0006 9 0 0 0 4.74E+06 3.68E+06 - - - 2.831 0.9982 221125_WJC_METTL3_EV_vs_WT_F01.19230.19230.2 0.0034 12-Jul R.EFEFLMR.Q sp|P85037|FOXK1_HUMAN 1 970.4582 0.93 6786 19230 2 970.457322 486.2364 Forkhead box protein K1 OS=Homo sapiens OX=9606 GN=FOXK1 PE=1 SV=1 4.53 3639.1 - 737361 - - - -0.9449 - 1.234 0.309 - 214.8 1 2 0 -0.0009 7 0 0 0 6.06E+06 6.49E+06 - - - 1.9892 0.9999 221125_WJC_METTL3_EV_vs_WT_F01.19232.19232.3 0.000148 Dec-48 R.IITLAGPTNAIFK[136.11].A "sp|Q15366|PCBP2_HUMAN,tr|F8W1G6|F8W1G6_HUMAN,tr|F8VZX2|F8VZX2_HUMAN,tr|F8W0G4|F8W0G4_HUMAN,tr|F8VXH9|F8VXH9_HUMAN,tr|H3BRU6|H3BRU6_HUMAN" 6 1365.8111 1.23 6788 19232 3 1365.810753 456.2777 Poly(rC)-binding protein 2 OS=Homo sapiens OX=9606 GN=PCBP2 PE=1 SV=1 8.75 3639.2 - 801649 - - - -0.2812 - 2.245 0.418 - 175.8 1 2 0 -0.0004 13 0 0 0 8.67E+06 7.08E+06 - - - 5.3928 0.9996 221125_WJC_METTL3_EV_vs_WT_F01.19233.19233.2 0.011 16-Sep R.MADLSELLK[136.11].E "sp|P30519|HMOX2_HUMAN,tr|I3L276|I3L276_HUMAN,tr|I3L159|I3L159_HUMAN,tr|I3L463|I3L463_HUMAN,tr|I3L4P8|I3L4P8_HUMAN,tr|A0A1B0GXH0|A0A1B0GXH0_HUMAN,tr|A0A087WT44|A0A087WT44_HUMAN,tr|I3L1F5|I3L1F5_HUMAN" 8 1026.5511 1.28 6789 19233 2 1026.550557 514.2828 Heme oxygenase 2 OS=Homo sapiens OX=9606 GN=HMOX2 PE=1 SV=2 4.37 3639.3 - 791258 - - - -0.5124 - 2.026 0.306 - 199 1 2 0 -0.0005 9 0 0 0 1.78E+07 1.39E+07 - - - 3.3436 0.9996 221125_WJC_METTL3_EV_vs_WT_F01.19235.19235.2 0.0012 18-Nov R.NALPALLIYK[136.11].G sp|Q13371|PHLP_HUMAN 1 1122.6892 0.31 6791 19235 2 1122.689963 562.3519 Phosducin-like protein OS=Homo sapiens OX=9606 GN=PDCL PE=1 SV=3 8.59 3639.6 - 664763 - - - 0.652 - 1.977 0.35 - 334.1 1 2 0 0.0007 10 0 0 0 2.16E+06 6.86E+06 - - - 3.5284 0.9128 221125_WJC_METTL3_EV_vs_WT_F01.19237.19237.2 0.635 22-Jun R.SPLLKSGPFGKK.Y sp|O95235|KI20A_HUMAN 1 1257.7445 999 6793 19237 2 1257.742334 629.8795 Kinesin-like protein KIF20A OS=Homo sapiens OX=9606 GN=KIF20A PE=1 SV=1 10.3 3639.9 - 420955 - - - -1.7285 - 1.435 0.156 - 104.9 1 2 1 -0.0022 12 0 0 0 5.24E+06 0.00E+00 - - - 1.1428 0.9997 221125_WJC_METTL3_EV_vs_WT_F01.19238.19238.2 5.36E-06 24-Sep R.LVSEFPYIEAEVK[136.11].Y sp|P43304|GPDM_HUMAN 1 1530.8061 0.38 6794 19238 2 1530.806603 766.4103 "Glycerol-3-phosphate dehydrogenase, mitochondrial OS=Homo sapiens OX=9606 GN=GPD2 PE=1 SV=3" 4.25 3640 - 270144 - - - 0.3207 - 1.949 0.385 - 183.4 1 2 0 0.0005 13 0 0 0 2.22E+06 5.85E+06 - - - 3.5971 0.9999 221125_WJC_METTL3_EV_vs_WT_F01.19242.19242.2 2.35E-07 20-Dec K.VGEVTYVELFK.D "sp|Q9P2K5|MYEF2_HUMAN,tr|A0A0A0MR39|A0A0A0MR39_HUMAN,tr|A0A087WUT0|A0A087WUT0_HUMAN,tr|A0A0A0MQW0|A0A0A0MQW0_HUMAN" 4 1282.6809 1.02 6796 19242 2 1282.680169 642.3477 Myelin expression factor 2 OS=Homo sapiens OX=9606 GN=MYEF2 PE=1 SV=3 4.53 3640.5 - 8.58E+06 - - - -0.5738 - 2.697 0.462 - 666.9 1 2 0 -0.0007 11 0 0 0 1.17E+08 1.14E+08 - - - 5.1371 0.9999 221125_WJC_METTL3_EV_vs_WT_F01.19243.19243.2 4.88E-06 20-Dec K.LGGNEIVSFLK[136.11].G "sp|O60762|DPM1_HUMAN,tr|A0A804HJ93|A0A804HJ93_HUMAN,tr|H0Y368|H0Y368_HUMAN,tr|Q5QPK2|Q5QPK2_HUMAN" 4 1183.6692 2.07 6797 19243 2 1183.668848 592.8419 Dolichol-phosphate mannosyltransferase subunit 1 OS=Homo sapiens OX=9606 GN=DPM1 PE=1 SV=1 6 3640.6 - 1.77E+06 - - - -0.3177 - 2.553 0.521 - 357.3 1 2 0 -0.0004 11 0 0 0 3.58E+07 1.73E+07 - - - 5.4245 0.9971 221125_WJC_METTL3_EV_vs_WT_F01.19244.19244.2 4.5 12-Jul R.EIFDLIR[166.11].S "sp|Q9Y3D0|CIA2B_HUMAN,tr|H3BNV7|H3BNV7_HUMAN,tr|J3KS95|J3KS95_HUMAN" 3 914.5101 1.88 6798 19244 2 914.509577 458.2623 Cytosolic iron-sulfur assembly component 2B OS=Homo sapiens OX=9606 GN=CIAO2B PE=1 SV=1 4.37 3640.7 - 1.84E+06 - - - -0.5588 - 1.509 0.162 - 234 1 2 0 -0.0005 7 0 0 0 8.24E+07 4.38E+07 - - - 1.5411 0.9997 221125_WJC_METTL3_EV_vs_WT_F01.19245.19245.2 0.00119 16-Sep K.GLMVLELPK.R "sp|Q99567|NUP88_HUMAN,tr|J3KMX1|J3KMX1_HUMAN" 2 998.5834 2.05 6799 19245 2 998.582302 500.299 Nuclear pore complex protein Nup88 OS=Homo sapiens OX=9606 GN=NUP88 PE=1 SV=2 6 3640.8 - 1.15E+06 - - - -1.1386 - 1.932 0.383 - 342.5 1 2 0 -0.0011 9 0 0 0 9.88E+06 4.81E+06 - - - 3.7747 0.9987 221125_WJC_METTL3_EV_vs_WT_F01.19248.19248.2 0.274 14-Aug R.LLFFAPTR[166.11].R sp|Q07820|MCL1_HUMAN 1 973.5625 1.03 6802 19248 2 973.561063 487.7885 Induced myeloid leukemia cell differentiation protein Mcl-1 OS=Homo sapiens OX=9606 GN=MCL1 PE=1 SV=3 9.75 3641.2 - 798072 - - - -1.4329 - 1.623 0.267 - 204.1 1 2 0 -0.0014 8 0 0 0 6.48E+06 6.28E+06 - - - 2.4732 0.9993 221125_WJC_METTL3_EV_vs_WT_F01.19250.19250.2 0.00296 18-Nov R.LIESLFTIQK[136.11].M "sp|Q12789|TF3C1_HUMAN,tr|H3BU37|H3BU37_HUMAN" 2 1198.7053 1.05 6804 19250 2 1198.707181 600.3599 General transcription factor 3C polypeptide 1 OS=Homo sapiens OX=9606 GN=GTF3C1 PE=1 SV=4 6 3641.5 - 568857 - - - 1.59 - 1.96 0.316 - 258.8 1 2 0 0.0019 10 0 0 0 6.53E+06 6.21E+06 - - - 3.2528 0.9997 221125_WJC_METTL3_EV_vs_WT_F01.19253.19253.2 2.97E-07 22-Oct K.LFGYEPTIYYPK.R "sp|Q8NCW5|NNRE_HUMAN,tr|A0A7P0Z426|A0A7P0Z426_HUMAN,tr|Q5T3I4|Q5T3I4_HUMAN,tr|A0A7P0T9Y2|A0A7P0T9Y2_HUMAN,tr|A0A7P0TAG8|A0A7P0TAG8_HUMAN,tr|Q5T3I3|Q5T3I3_HUMAN" 6 1489.7493 0.98 6807 19253 2 1489.745882 745.8819 NAD(P)H-hydrate epimerase OS=Homo sapiens OX=9606 GN=NAXE PE=1 SV=2 6 3641.9 - 426960 - - - -2.3071 - 2.154 0.525 - 272.7 1 2 0 -0.0034 12 0 0 0 4.42E+06 4.50E+06 - - - 4.9365 0.9995 221125_WJC_METTL3_EV_vs_WT_F01.19254.19254.2 0.00594 20-Aug R.AFSLASADLLR.A sp|Q9P219|DAPLE_HUMAN 1 1162.6346 1.15 6808 19254 2 1162.633289 582.3246 Protein Daple OS=Homo sapiens OX=9606 GN=CCDC88C PE=1 SV=3 5.88 3642 - 294807 - - - -1.1474 - 1.55 0.41 - 134.6 1 2 0 -0.0013 11 0 0 0 3.51E+06 3.06E+06 - - - 3.2544 0.9034 221125_WJC_METTL3_EV_vs_WT_F01.19256.19256.2 2.64 18-May R.LEMLGDSFLK[136.11].H "sp|Q9UPY3|DICER_HUMAN,tr|A0A7I2YBM0|A0A7I2YBM0_HUMAN,tr|H0YJZ6|H0YJZ6_HUMAN" 3 1159.6038 0.37 6810 19256 2 1159.602054 580.8092 Endoribonuclease Dicer OS=Homo sapiens OX=9606 GN=DICER1 PE=1 SV=3 4.37 3642.2 - 379381 - - - -1.5462 - 1.246 0.028 - 44.7 10 2 0 -0.0018 10 0 0 0 8.88E+05 2.42E+06 - - - -0.5855 1 221125_WJC_METTL3_EV_vs_WT_F01.19259.19259.2 2.80E-07 13/20 K.VGEVTYVELFK[136.11].D "sp|Q9P2K5|MYEF2_HUMAN,tr|A0A0A0MR39|A0A0A0MR39_HUMAN,tr|A0A087WUT0|A0A087WUT0_HUMAN,tr|A0A0A0MQW0|A0A0A0MQW0_HUMAN" 4 1290.6951 1.02 6811 19259 2 1290.694769 646.3548 Myelin expression factor 2 OS=Homo sapiens OX=9606 GN=MYEF2 PE=1 SV=3 4.53 3642.6 - 1.52E+07 - - - -0.2603 - 2.671 0.595 - 797.9 1 2 0 -0.0003 11 0 0 0 1.17E+08 1.14E+08 - - - 6.0933 0.9999 221125_WJC_METTL3_EV_vs_WT_F01.19266.19266.2 1.43E-06 22-Oct K.LFGYEPTIYYPK[136.11].R "sp|Q8NCW5|NNRE_HUMAN,tr|A0A7P0Z426|A0A7P0Z426_HUMAN,tr|Q5T3I4|Q5T3I4_HUMAN,tr|A0A7P0T9Y2|A0A7P0T9Y2_HUMAN,tr|A0A7P0TAG8|A0A7P0TAG8_HUMAN,tr|Q5T3I3|Q5T3I3_HUMAN" 6 1497.7635 0.98 6818 19266 2 1497.762353 749.889 NAD(P)H-hydrate epimerase OS=Homo sapiens OX=9606 GN=NAXE PE=1 SV=2 6 3643.4 - 576314 - - - -0.7785 - 2.217 0.538 - 285.8 1 2 0 -0.0012 12 0 0 0 4.42E+06 4.50E+06 - - - 5.1091 0.9996 221125_WJC_METTL3_EV_vs_WT_F01.19267.19267.2 0.00182 24-Nov R.LVSEFPYIEAEVK.Y sp|P43304|GPDM_HUMAN 1 1522.7919 0.4 6819 19267 2 1522.791233 762.4032 "Glycerol-3-phosphate dehydrogenase, mitochondrial OS=Homo sapiens OX=9606 GN=GPD2 PE=1 SV=3" 4.25 3643.6 - 437450 - - - -0.4459 - 1.916 0.357 - 199.6 1 2 0 -0.0007 13 0 0 0 2.22E+06 5.61E+06 - - - 3.3464 0.9999 221125_WJC_METTL3_EV_vs_WT_F01.19269.19269.2 4.31E-07 13/24 R.VESPVLPPVLVPR[166.11].H "sp|Q99717|SMAD5_HUMAN,sp|Q15797|SMAD1_HUMAN" 2 1410.8474 1.63 6821 19269 2 1410.846092 706.431 Mothers against decapentaplegic homolog 5 OS=Homo sapiens OX=9606 GN=SMAD5 PE=1 SV=1 5.97 3643.8 - 297997 - - - -0.9321 - 2.339 0.586 - 352.3 1 2 0 -0.0013 13 0 0 0 1.73E+07 1.06E+07 - - - 5.5496 0.9989 221125_WJC_METTL3_EV_vs_WT_F01.19270.19270.2 0.0018 20-Sep K.TYVGGILLLSK[136.11].Q sp|Q9UBV7|B4GT7_HUMAN 1 1170.7104 0.9 6822 19270 2 1170.708989 586.3625 "Beta-1,4-galactosyltransferase 7 OS=Homo sapiens OX=9606 GN=B4GALT7 PE=1 SV=1" 8.26 3643.9 - 288206 - - - -1.1719 - 1.439 0.34 - 154.6 1 2 0 -0.0014 11 0 0 0 1.25E+06 1.39E+06 - - - 2.5364 1 221125_WJC_METTL3_EV_vs_WT_F01.19271.19271.2 2.33E-06 13/24 R.TPFTTAQLLALER[166.11].K sp|P28360|MSX1_HUMAN 1 1469.8117 1.69 6823 19271 2 1469.813064 735.9132 Homeobox protein MSX-1 OS=Homo sapiens OX=9606 GN=MSX1 PE=1 SV=3 5.66 3644.1 - 280506 - - - 0.8947 - 2.899 0.581 - 547.8 1 2 0 0.0013 13 0 0 0 8.09E+06 4.80E+06 - - - 6.0636 0.9997 221125_WJC_METTL3_EV_vs_WT_F01.19276.19276.2 0.0296 18-Sep K.IELFADVVPK[136.11].T "sp|O43447|PPIH_HUMAN,tr|A0A7I2V2H6|A0A7I2V2H6_HUMAN,tr|A0A7I2V343|A0A7I2V343_HUMAN,tr|A0A7I2V5V0|A0A7I2V5V0_HUMAN,tr|C9JQD4|C9JQD4_HUMAN" 5 1137.6525 2.85 6827 19276 2 1137.653384 569.8335 Peptidyl-prolyl cis-trans isomerase H OS=Homo sapiens OX=9606 GN=PPIH PE=1 SV=1 4.37 3644.5 - 3.46E+06 - - - 0.7674 - 2.117 0.361 - 201.8 1 2 0 0.0009 10 0 0 0 1.26E+08 4.43E+07 - - - 3.8005 0.9997 221125_WJC_METTL3_EV_vs_WT_F01.19277.19277.2 0.083 18-Nov R.AEVVSLLLDR[166.11].K "sp|Q8IWZ3|ANKH1_HUMAN,tr|E9PDP5|E9PDP5_HUMAN,tr|H3BLS9|H3BLS9_HUMAN,tr|H7C2F5|H7C2F5_HUMAN" 4 1123.6476 2.62 6828 19277 2 1123.647828 562.8311 Ankyrin repeat and KH domain-containing protein 1 OS=Homo sapiens OX=9606 GN=ANKHD1 PE=1 SV=1 4.37 3644.6 - 3.19E+06 - - - 0.1638 - 2.128 0.326 - 623.4 1 2 0 0.0002 10 0 0 0 1.27E+08 4.86E+07 - - - 3.5567 0.9998 221125_WJC_METTL3_EV_vs_WT_F01.19279.19279.2 0.00253 18-Oct K.LTLSALIDGK[136.11].N "sp|Q9Y277|VDAC3_HUMAN,sp|P21796|VDAC1_HUMAN" 2 1037.6212 1.5 6830 19279 2 1037.621577 519.8179 Voltage-dependent anion-selective channel protein 3 OS=Homo sapiens OX=9606 GN=VDAC3 PE=1 SV=1 5.84 3644.8 - 1.12E+06 - - - 0.3527 - 2.141 0.402 - 220 1 2 0 0.0004 10 0 0 0 1.16E+07 7.69E+06 - - - 4.135 0.9999 221125_WJC_METTL3_EV_vs_WT_F01.19280.19280.2 0.0884 20-Nov R.VLITTLITAGR[166.11].L "sp|Q9HCE1|MOV10_HUMAN,tr|Q5JR04|Q5JR04_HUMAN" 2 1166.7262 0.98 6831 19280 2 1166.72641 584.3704 Helicase MOV-10 OS=Homo sapiens OX=9606 GN=MOV10 PE=1 SV=2 9.72 3644.9 - 912200 - - - 0.1551 - 2.378 0.448 - 340.9 1 2 0 0.0002 11 0 0 0 7.60E+06 7.74E+06 - - - 4.6933 1 221125_WJC_METTL3_EV_vs_WT_F01.19281.19281.2 3.33E-09 17/24 R.TPFTTAQLLALER.K sp|P28360|MSX1_HUMAN 1 1459.8035 1.69 6832 19281 2 1459.804185 730.909 Homeobox protein MSX-1 OS=Homo sapiens OX=9606 GN=MSX1 PE=1 SV=3 5.66 3645.1 - 876042 - - - 0.4836 - 3.274 0.559 - 1346.8 1 2 0 0.0007 13 0 0 0 8.09E+06 4.80E+06 - - - 6.2135 0.9513 221125_WJC_METTL3_EV_vs_WT_F01.19283.19283.2 2.64 16-Jun K.DAVAVWNGR[166.11].Q sp|Q96RY7|IF140_HUMAN 1 996.5016 0.03 6834 19283 2 996.501897 499.2581 Intraflagellar transport protein 140 homolog OS=Homo sapiens OX=9606 GN=IFT140 PE=1 SV=1 5.84 3645.3 - 618741 - - - 0.2489 - 1.225 0.014 - 107.8 2 2 0 0.0002 9 0 0 0 1.11E+05 3.66E+06 - - - -0.403 0.9997 221125_WJC_METTL3_EV_vs_WT_F01.19285.19285.2 9.04E-07 16/24 R.ILDIDNVDLAMGK[136.11].M sp|O43615|TIM44_HUMAN 1 1423.7472 1.07 6836 19285 2 1423.750229 712.8809 Mitochondrial import inner membrane translocase subunit TIM44 OS=Homo sapiens OX=9606 GN=TIMM44 PE=1 SV=2 3.93 3645.6 - 487330 - - - 2.1155 - 2.946 0.43 - 744.8 1 2 0 0.003 13 0 0 0 3.54E+07 3.32E+07 - - - 4.989 0.9933 221125_WJC_METTL3_EV_vs_WT_F01.19292.19292.2 0.000405 22-Dec K.VIHDNFGIVEGL.M "sp|P04406|G3P_HUMAN,tr|E7EUT5|E7EUT5_HUMAN" 2 1311.6823 - 6841 19292 2 1311.682415 656.8484 Glyceraldehyde-3-phosphate dehydrogenase OS=Homo sapiens OX=9606 GN=GAPDH PE=1 SV=3 4.35 3646.5 - 1.07E+07 - - - 0.0861 - 2.372 0.5 - 542 1 1 0 0.0001 12 0 0 0 - - - - - 5.0066 1 221125_WJC_METTL3_EV_vs_WT_F01.19293.19293.2 2.77E-05 13/24 R.ILDIDNVDLAMGK.M sp|O43615|TIM44_HUMAN 1 1415.733 1.07 6842 19293 2 1415.733039 708.8738 Mitochondrial import inner membrane translocase subunit TIM44 OS=Homo sapiens OX=9606 GN=TIMM44 PE=1 SV=2 3.93 3646.5 - 3.07E+06 - - - 0.0155 - 2.703 0.602 - 552.8 1 2 0 0 13 0 0 0 3.54E+07 3.32E+07 - - - 6.0394 0.9998 221125_WJC_METTL3_EV_vs_WT_F01.19296.19296.2 0.00492 20-Dec R.VLITTLITAGR.L "sp|Q9HCE1|MOV10_HUMAN,tr|Q5JR04|Q5JR04_HUMAN" 2 1156.718 0.98 6845 19296 2 1156.716983 579.3663 Helicase MOV-10 OS=Homo sapiens OX=9606 GN=MOV10 PE=1 SV=2 9.72 3646.8 - 1.52E+06 - - - -0.8438 - 2.406 0.348 - 504.7 1 2 0 -0.001 11 0 0 0 7.60E+06 7.74E+06 - - - 3.9861 0.9999 221125_WJC_METTL3_EV_vs_WT_F01.19297.19297.2 3.19E-07 14/24 R.VESPVLPPVLVPR.H "sp|Q99717|SMAD5_HUMAN,sp|Q15797|SMAD1_HUMAN" 2 1400.8391 1.63 6846 19297 2 1400.83897 701.4268 Mothers against decapentaplegic homolog 5 OS=Homo sapiens OX=9606 GN=SMAD5 PE=1 SV=1 5.97 3646.9 - 1.31E+06 - - - -0.1192 - 2.567 0.517 - 449.5 1 2 0 -0.0002 13 0 0 0 1.73E+07 1.06E+07 - - - 5.2791 0.9998 221125_WJC_METTL3_EV_vs_WT_F01.19300.19300.2 6.54E-05 16-Sep R.GWAPVFLDR[166.11].E "sp|Q9Y5Y2|NUBP2_HUMAN,tr|H3BQR2|H3BQR2_HUMAN,tr|H3BRE1|H3BRE1_HUMAN,tr|H3BNF0|H3BNF0_HUMAN,tr|H3BNS4|H3BNS4_HUMAN" 5 1069.5584 1.53 6849 19300 2 1069.559609 535.7865 Cytosolic Fe-S cluster assembly factor NUBP2 OS=Homo sapiens OX=9606 GN=NUBP2 PE=1 SV=1 5.84 3647.1 - 876088 - - - 1.0976 - 1.914 0.464 - 435.2 1 2 0 0.0012 9 0 0 0 1.08E+07 7.06E+06 - - - 4.3459 0.9236 221125_WJC_METTL3_EV_vs_WT_F01.19301.19301.2 7.46 16-May K.LILDFLNSK.K "sp|O94967|WDR47_HUMAN,tr|E9PKZ6|E9PKZ6_HUMAN,tr|A0A0A0MRE6|A0A0A0MRE6_HUMAN,tr|E9PR96|E9PR96_HUMAN" 4 1061.6121 0.86 6850 19301 2 1061.612704 531.8133 WD repeat-containing protein 47 OS=Homo sapiens OX=9606 GN=WDR47 PE=1 SV=1 5.84 3647.2 - 866446 - - - 0.5718 - 1.192 0.031 - 47.7 9 2 0 0.0006 9 0 0 0 3.74E+06 4.35E+06 - - - -0.6484 0.9989 221125_WJC_METTL3_EV_vs_WT_F01.19302.19302.2 0.0283 12-May R.EAYFWLR[166.11].Q sp|Q8TCJ2|STT3B_HUMAN 1 993.4948 0.81 6851 19302 2 993.494927 497.7547 Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit STT3B OS=Homo sapiens OX=9606 GN=STT3B PE=1 SV=1 6.1 3647.3 - 608578 - - - 0.156 - 1.24 0.354 - 108.4 1 2 0 0.0002 7 0 0 0 3.12E+06 3.87E+06 - - - 2.3372 0.9969 221125_WJC_METTL3_EV_vs_WT_F01.19304.19304.3 0.00277 13/48 R.TPFTTAQLLALER.K sp|P28360|MSX1_HUMAN 1 1459.8035 1.67 6853 19304 3 1459.804676 487.6084 Homeobox protein MSX-1 OS=Homo sapiens OX=9606 GN=MSX1 PE=1 SV=3 5.66 3647.5 - 538538 - - - 0.82 - 2.138 0.175 - 276 1 2 0 0.0012 13 0 0 0 2.29E+06 1.37E+06 - - - 2.551 0.9975 221125_WJC_METTL3_EV_vs_WT_F01.19307.19307.2 2.26 14-Jul K.SLLAGLLK[136.11].K "sp|P31751|AKT2_HUMAN,tr|M0R0P9|M0R0P9_HUMAN,tr|J3QKW1|J3QKW1_HUMAN,tr|J3QL45|J3QL45_HUMAN,tr|M0R283|M0R283_HUMAN,tr|M0QZW8|M0QZW8_HUMAN" 6 821.5466 1.4 6856 19307 2 821.546724 411.7806 RAC-beta serine\threonine-protein kinase OS=Homo sapiens OX=9606 GN=AKT2 PE=1 SV=2 8.47 3647.9 - 452425 - - - 0.1631 - 1.371 0.22 - 156.6 1 2 0 0.0001 8 0 0 0 2.41E+06 1.72E+06 - - - 1.6175 0.9996 221125_WJC_METTL3_EV_vs_WT_F01.19318.19318.2 0.00368 14-Sep R.YELALILK[136.11].A sp|P82932|RT06_HUMAN 1 969.599 0.77 6866 19318 2 969.598964 485.8068 "28S ribosomal protein S6, mitochondrial OS=Homo sapiens OX=9606 GN=MRPS6 PE=1 SV=3" 6 3649 - 1.22E+06 - - - -0.0567 - 1.674 0.373 - 188.8 1 2 0 -0.0001 8 0 0 0 4.78E+06 6.18E+06 - - - 3.3498 0.9998 221125_WJC_METTL3_EV_vs_WT_F01.19319.19319.2 4.17E-05 14-Aug R.NYFGLFPR[166.11].V sp|Q8WUF5|IASPP_HUMAN 1 1022.5213 2.04 6867 19319 2 1022.520852 512.2679 RelA-associated inhibitor OS=Homo sapiens OX=9606 GN=PPP1R13L PE=1 SV=4 8.75 3649.1 - 1.19E+06 - - - -0.4587 - 1.714 0.52 - 298.2 1 2 0 -0.0005 8 0 0 0 1.60E+07 7.83E+06 - - - 4.5067 0.9997 221125_WJC_METTL3_EV_vs_WT_F01.19320.19320.2 0.000384 14-Oct R.YELALILK.A sp|P82932|RT06_HUMAN 1 961.5848 0.74 6868 19320 2 961.585103 481.7997 "28S ribosomal protein S6, mitochondrial OS=Homo sapiens OX=9606 GN=MRPS6 PE=1 SV=3" 6 3649.2 - 875804 - - - 0.2953 - 1.751 0.371 - 265.4 1 2 0 0.0003 8 0 0 0 4.78E+06 6.48E+06 - - - 3.4706 0.7959 221125_WJC_METTL3_EV_vs_WT_F01.19321.19321.2 1.46 14-Jul S.GVLSSIGK[136.11].L "sp|Q9NZJ7|MTCH1_HUMAN,tr|H0Y8C3|H0Y8C3_HUMAN,tr|H7C196|H7C196_HUMAN" 3 767.4633 0.58 6869 19321 2 767.462983 384.7389 Mitochondrial carrier homolog 1 OS=Homo sapiens OX=9606 GN=MTCH1 PE=1 SV=1 8.75 3649.4 - 872748 - - - -0.3531 - 1.279 0.195 - 144 1 1 0 -0.0003 8 0 0 0 2.34E+06 4.00E+06 - - - 1.2233 0.8912 221125_WJC_METTL3_EV_vs_WT_F01.19322.19322.2 3.31 26-Jun K.VVIGMDVAASEFYR.N "sp|P13929|ENOB_HUMAN,tr|E5RGZ4|E5RGZ4_HUMAN" 2 1555.7705 1.63 6870 19322 2 1555.771426 778.8925 Beta-enolase OS=Homo sapiens OX=9606 GN=ENO3 PE=1 SV=5 4.37 3649.5 - 792550 - - - 0.6177 - 0.91 0.043 - 74.9 1 2 0 0.001 14 0 0 0 3.28E+07 2.01E+07 - - - -0.8784 0.9999 221125_WJC_METTL3_EV_vs_WT_F01.19324.19324.3 0.0015 Dec-48 R.VESPVLPPVLVPR.H "sp|Q99717|SMAD5_HUMAN,sp|Q15797|SMAD1_HUMAN" 2 1400.8391 1.82 6872 19324 3 1400.839399 467.9537 Mothers against decapentaplegic homolog 5 OS=Homo sapiens OX=9606 GN=SMAD5 PE=1 SV=1 5.97 3649.7 - 629340 - - - 0.187 - 2.279 0.381 - 257.7 1 2 0 0.0003 13 0 0 0 4.60E+06 2.53E+06 - - - 5.0211 0.9641 221125_WJC_METTL3_EV_vs_WT_F01.19325.19325.2 1.13 26-Jul K.VVIGMDVAASEFYR[166.11].N "sp|P13929|ENOB_HUMAN,tr|E5RGZ4|E5RGZ4_HUMAN" 2 1565.7787 1.63 6873 19325 2 1565.77685 783.8966 Beta-enolase OS=Homo sapiens OX=9606 GN=ENO3 PE=1 SV=5 4.37 3649.8 - 611785 - - - -1.2039 - 1.052 0.106 - 98.3 1 2 0 -0.0019 14 0 0 0 3.28E+07 2.01E+07 - - - -0.0495 1 221125_WJC_METTL3_EV_vs_WT_F01.19328.19328.2 9.88E-08 14/26 K.LPIGDVATQYFADR[166.11].D sp|Q99832|TCPH_HUMAN 1 1574.7968 0.19 6876 19328 2 1574.79668 788.4057 T-complex protein 1 subunit eta OS=Homo sapiens OX=9606 GN=CCT7 PE=1 SV=2 4.21 3650.2 - 324026 - - - -0.094 - 2.639 0.622 - 498 1 2 0 -0.0001 14 0 0 0 9.55E+05 5.08E+06 - - - 6.0702 0.998 221125_WJC_METTL3_EV_vs_WT_F01.19335.19335.2 0.0133 22-Oct K.TPLPPELADVQA.- "sp|Q9Y5V0|ZN706_HUMAN,tr|H0YC70|H0YC70_HUMAN" 2 1249.6554 - 6882 19335 2 1249.651992 625.835 Zinc finger protein 706 OS=Homo sapiens OX=9606 GN=ZNF706 PE=1 SV=1 3.67 3651.1 - 981174 - - - -2.7416 - 1.819 0.314 - 330.9 1 2 0 -0.0034 12 0 0 0 - - - - - 2.9333 0.9995 221125_WJC_METTL3_EV_vs_WT_F01.19336.19336.2 0.0104 18-Sep R.AEVVSLLLDR.K "sp|Q8IWZ3|ANKH1_HUMAN,tr|E9PDP5|E9PDP5_HUMAN,tr|H3BLS9|H3BLS9_HUMAN,tr|H7C2F5|H7C2F5_HUMAN" 4 1113.6394 2.62 6883 19336 2 1113.638786 557.827 Ankyrin repeat and KH domain-containing protein 1 OS=Homo sapiens OX=9606 GN=ANKHD1 PE=1 SV=1 4.37 3651.1 - 1.34E+07 - - - -0.528 - 1.66 0.343 - 362.7 1 2 0 -0.0006 10 0 0 0 1.27E+08 4.86E+07 - - - 2.9889 0.9997 221125_WJC_METTL3_EV_vs_WT_F01.19337.19337.2 0.00559 18-Sep R.EALLAALGYK.N sp|Q9BU76|MMTA2_HUMAN 1 1047.5964 0.79 6884 19337 2 1047.595954 524.8055 Multiple myeloma tumor-associated protein 2 OS=Homo sapiens OX=9606 GN=MMTAG2 PE=1 SV=1 6.1 3651.2 - 2.45E+06 - - - -0.4706 - 1.941 0.38 - 233.8 1 2 0 -0.0005 10 0 0 0 8.96E+06 1.14E+07 - - - 3.6987 0.9998 221125_WJC_METTL3_EV_vs_WT_F01.19338.19338.2 0.0177 16-Oct K.TFDPYIIIR[166.11].A sp|Q13601|KRR1_HUMAN 1 1146.6313 0.65 6885 19338 2 1146.630369 574.3229 KRR1 small subunit processome component homolog OS=Homo sapiens OX=9606 GN=KRR1 PE=1 SV=4 5.5 3651.3 - 2.23E+06 - - - -0.7823 - 2.081 0.389 - 390.5 1 2 0 -0.0009 9 0 0 0 7.89E+06 1.21E+07 - - - 4.034 0.9999 221125_WJC_METTL3_EV_vs_WT_F01.19340.19340.2 3.85E-07 22-Dec R.ELYLEDSPLELK.L sp|Q8TEM1|PO210_HUMAN 1 1447.7446 1.76 6887 19340 2 1447.745624 724.8796 Nuclear pore membrane glycoprotein 210 OS=Homo sapiens OX=9606 GN=NUP210 PE=1 SV=3 4 3651.4 - 1.59E+06 - - - 0.6887 - 2.339 0.554 - 419.8 1 2 0 0.001 12 0 0 0 1.63E+07 9.29E+06 - - - 5.3683 0.9992 221125_WJC_METTL3_EV_vs_WT_F01.19343.19343.2 0.0104 14-Aug K.GILVFQLK[136.11].R "sp|P55196|AFAD_HUMAN,tr|J3KN01|J3KN01_HUMAN,tr|H0Y7R8|H0Y7R8_HUMAN,tr|A0A804HJ20|A0A804HJ20_HUMAN,tr|Q5TIG5|Q5TIG5_HUMAN,tr|A8MQ02|A8MQ02_HUMAN" 6 924.5888 0.52 6890 19343 2 924.588494 463.3017 Afadin OS=Homo sapiens OX=9606 GN=AFDN PE=1 SV=3 8.75 3651.7 - 938565 - - - -0.3191 - 1.772 0.242 - 198.2 1 2 0 -0.0003 8 0 0 0 1.92E+06 3.70E+06 - - - 2.5538 0.9999 221125_WJC_METTL3_EV_vs_WT_F01.19344.19344.2 2.35E-07 20-Oct R.GWDEALLTMSK[136.11].G sp|Q00688|FKBP3_HUMAN 1 1257.6155 0.05 6891 19344 2 1257.615293 629.815 Peptidyl-prolyl cis-trans isomerase FKBP3 OS=Homo sapiens OX=9606 GN=FKBP3 PE=1 SV=1 4.37 3651.8 - 896863 - - - -0.1439 - 2.075 0.557 - 386.3 1 2 0 -0.0002 11 0 0 0 1.83E+05 3.74E+06 - - - 5.1297 0.9936 221125_WJC_METTL3_EV_vs_WT_F01.19345.19345.2 0.237 12-Jul K.LTFLDLR[166.11].N "sp|Q9H9A6|LRC40_HUMAN,tr|X6R5P2|X6R5P2_HUMAN" 2 886.5152 1.64 6892 19345 2 886.514697 444.2649 Leucine-rich repeat-containing protein 40 OS=Homo sapiens OX=9606 GN=LRRC40 PE=1 SV=1 5.84 3651.9 - 888996 - - - -0.5369 - 1.487 0.088 - 191.6 1 2 0 -0.0005 7 0 0 0 8.90E+06 5.44E+06 - - - 0.948 0.889 221125_WJC_METTL3_EV_vs_WT_F01.19346.19346.2 0.0056 12-Jun K.SLLVVHF.W sp|O76003|GLRX3_HUMAN 1 813.4749 - 6893 19346 2 813.473995 407.7447 Glutaredoxin-3 OS=Homo sapiens OX=9606 GN=GLRX3 PE=1 SV=2 6.46 3652 - 693978 - - - -1.0818 - 1.095 0.353 - 109.3 1 1 0 -0.0009 7 0 0 0 - - - - - 1.9355 0.9923 221125_WJC_METTL3_EV_vs_WT_F01.19348.19348.2 0.297 14-Aug K.LLILALER.L "sp|Q6P2Q9|PRP8_HUMAN,tr|I3L0J9|I3L0J9_HUMAN" 2 939.6117 1.37 6895 19348 2 939.611192 470.8131 Pre-mRNA-processing-splicing factor 8 OS=Homo sapiens OX=9606 GN=PRPF8 PE=1 SV=2 6 3652.3 - 670297 - - - -0.5438 - 1.606 0.066 - 181.9 2 2 0 -0.0005 8 0 0 0 9.89E+06 7.21E+06 - - - 0.8226 0.9999 221125_WJC_METTL3_EV_vs_WT_F01.19349.19349.2 0.00027 13/22 R.SQPAILLLTAAR[166.11].D "sp|Q5JTV8|TOIP1_HUMAN,tr|H0Y4R4|H0Y4R4_HUMAN,tr|J3KN66|J3KN66_HUMAN,tr|A0A0A0MSK5|A0A0A0MSK5_HUMAN" 4 1262.7586 1.55 6896 19349 2 1262.758844 632.3866 Torsin-1A-interacting protein 1 OS=Homo sapiens OX=9606 GN=TOR1AIP1 PE=1 SV=2 9.47 3652.4 - 514262 - - - 0.1996 - 2.463 0.485 - 691.2 1 2 0 0.0003 12 0 0 0 5.81E+06 3.75E+06 - - - 4.9948 0.9871 221125_WJC_METTL3_EV_vs_WT_F01.19353.19353.2 0.102 20-Aug R.DPIPYLPPLEK.L sp|P08621|RU17_HUMAN 1 1280.7016 2.4 6900 19353 2 1280.706414 641.3581 U1 small nuclear ribonucleoprotein 70 kDa OS=Homo sapiens OX=9606 GN=SNRNP70 PE=1 SV=2 4.37 3652.9 - 343529 - - - 3.7276 - 1.781 0.181 - 222.1 1 2 0 0.0048 11 0 0 0 2.47E+06 1.03E+06 - - - 1.9378 0.9998 221125_WJC_METTL3_EV_vs_WT_F01.19355.19355.2 0.000501 18-Nov R.VIVVWFQNAR.Q "sp|Q86UP3|ZFHX4_HUMAN,sp|Q15911|ZFHX3_HUMAN,tr|E7EVZ1|E7EVZ1_HUMAN" 3 1230.6873 1.84 6901 19355 2 1230.688106 616.3509 Zinc finger homeobox protein 4 OS=Homo sapiens OX=9606 GN=ZFHX4 PE=1 SV=1 9.72 3653.2 - 1.74E+06 - - - 0.633 - 2.076 0.411 - 539 1 2 0 0.0008 10 0 0 0 7.41E+06 4.03E+06 - - - 4.1153 0.997 221125_WJC_METTL3_EV_vs_WT_F01.19358.19358.2 0.507 12-Jul K.LTFLDLR.N "sp|Q9H9A6|LRC40_HUMAN,tr|X6R5P2|X6R5P2_HUMAN" 2 876.5069 1.64 6904 19358 2 876.507073 439.2607 Leucine-rich repeat-containing protein 40 OS=Homo sapiens OX=9606 GN=LRRC40 PE=1 SV=1 5.84 3653.4 - 2.38E+06 - - - 0.194 - 1.557 0.143 - 177.2 1 2 0 0.0002 7 0 0 0 8.90E+06 5.44E+06 - - - 1.5001 0.9997 221125_WJC_METTL3_EV_vs_WT_F01.19360.19360.2 0.0156 18-Oct R.EALLAALGYK[136.11].N sp|Q9BU76|MMTA2_HUMAN 1 1055.6106 0.78 6906 19360 2 1055.610205 528.8126 Multiple myeloma tumor-associated protein 2 OS=Homo sapiens OX=9606 GN=MMTAG2 PE=1 SV=1 6.1 3653.6 - 1.85E+06 - - - -0.4187 - 2.165 0.324 - 264.3 1 2 0 -0.0004 10 0 0 0 8.96E+06 1.14E+07 - - - 3.59 0.9992 221125_WJC_METTL3_EV_vs_WT_F01.19362.19362.2 0.239 14-Sep K.LLILALER[166.11].L "sp|Q6P2Q9|PRP8_HUMAN,tr|I3L0J9|I3L0J9_HUMAN" 2 949.62 1.37 6908 19362 2 949.620157 475.8173 Pre-mRNA-processing-splicing factor 8 OS=Homo sapiens OX=9606 GN=PRPF8 PE=1 SV=2 6 3653.7 - 1.37E+06 - - - 0.1938 - 1.657 0.273 - 293.4 1 2 0 0.0002 8 0 0 0 9.89E+06 7.21E+06 - - - 2.5804 0.9997 221125_WJC_METTL3_EV_vs_WT_F01.19363.19363.2 0.000947 18-Sep R.TALYNYIFAK.K "sp|Q5JPH6|SYEM_HUMAN,tr|H3BTB7|H3BTB7_HUMAN" 2 1202.6336 1.14 6909 19363 2 1202.631383 602.3241 "Probable glutamate--tRNA ligase, mitochondrial OS=Homo sapiens OX=9606 GN=EARS2 PE=1 SV=2" 8.17 3653.8 - 1.09E+06 - - - -1.8102 - 1.957 0.464 - 251.5 1 2 0 -0.0022 10 0 0 0 5.77E+06 5.05E+06 - - - 4.3415 0.9999 221125_WJC_METTL3_EV_vs_WT_F01.19364.19364.2 3.08E-07 15/20 R.LLESLDQLELR.V sp|O95816|BAG2_HUMAN 1 1327.7347 0.24 6910 19364 2 1327.735814 664.8746 BAG family molecular chaperone regulator 2 OS=Homo sapiens OX=9606 GN=BAG2 PE=1 SV=1 4.14 3653.9 - 1.00E+06 - - - 0.8157 - 2.696 0.449 - 856.6 1 2 0 0.0011 11 0 0 0 2.89E+07 1.22E+08 - - - 5.0399 0.806 221125_WJC_METTL3_EV_vs_WT_F01.19366.19366.2 0.144 12-Jun K.LQSIQPL.T tr|C9JG08|C9JG08_HUMAN 1 797.4647 - 6912 19366 2 797.464627 399.7396 Uncharacterized protein C2orf16 OS=Homo sapiens OX=9606 GN=C2orf16 PE=1 SV=2 5.52 3654.2 - 978176 - - - -0.0966 - 1.249 0.205 - 144.3 1 1 0 -0.0001 7 0 0 0 - - - - - 1.2596 0.9992 221125_WJC_METTL3_EV_vs_WT_F01.19367.19367.2 0.0303 14-Aug R.GLDIYVWR[166.11].G sp|Q13045|FLII_HUMAN 1 1030.5475 0.89 6913 19367 2 1030.548877 516.281 Protein flightless-1 homolog OS=Homo sapiens OX=9606 GN=FLII PE=1 SV=2 5.84 3654.3 - 913796 - - - 1.3013 - 1.77 0.296 - 282.1 1 2 0 0.0013 8 0 0 0 4.65E+06 5.24E+06 - - - 2.9489 0.9999 221125_WJC_METTL3_EV_vs_WT_F01.19370.19370.2 0.000993 14/26 R.LIVVLEGASLETVK[136.11].V "sp|Q92979|NEP1_HUMAN,tr|V9GYP5|V9GYP5_HUMAN,tr|A0A087WWQ2|A0A087WWQ2_HUMAN" 3 1477.8847 0.8 6916 19370 2 1477.88508 739.9496 Ribosomal RNA small subunit methyltransferase NEP1 OS=Homo sapiens OX=9606 GN=EMG1 PE=1 SV=4 4.53 3654.7 - 599272 - - - 0.2598 - 2.728 0.449 - 564.3 1 2 0 0.0004 14 0 0 0 2.33E+06 2.92E+06 - - - 4.8756 0.9999 221125_WJC_METTL3_EV_vs_WT_F01.19371.19371.2 0.00121 15/28 R.VGPDVVTDPAFLVTR.S sp|Q9NV31|IMP3_HUMAN 1 1584.8512 1.29 6917 19371 2 1584.85246 793.4329 U3 small nucleolar ribonucleoprotein protein IMP3 OS=Homo sapiens OX=9606 GN=IMP3 PE=1 SV=1 4.21 3654.8 - 490953 - - - 0.8215 - 2.483 0.532 - 440.7 1 2 0 0.0013 15 0 0 0 1.59E+07 1.23E+07 - - - 5.2059 0.9995 221125_WJC_METTL3_EV_vs_WT_F01.19372.19372.2 0.0151 20-Dec R.LALVISELEGK[136.11].A "sp|Q12899|TRI26_HUMAN,tr|A2AE48|A2AE48_HUMAN" 2 1178.7002 1.22 6918 19372 2 1178.701602 590.3574 Tripartite motif-containing protein 26 OS=Homo sapiens OX=9606 GN=TRIM26 PE=1 SV=1 4.53 3654.9 - 473177 - - - 1.1979 - 2.485 0.255 - 450.9 1 2 0 0.0014 11 0 0 0 5.48E+06 4.51E+06 - - - 3.3865 0.9999 221125_WJC_METTL3_EV_vs_WT_F01.19374.19374.2 4.70E-05 16/28 R.VGPDVVTDPAFLVTR[166.11].S sp|Q9NV31|IMP3_HUMAN 1 1594.8594 1.29 6920 19374 2 1594.861242 798.437 U3 small nucleolar ribonucleoprotein protein IMP3 OS=Homo sapiens OX=9606 GN=IMP3 PE=1 SV=1 4.21 3655.2 - 448304 - - - 1.1374 - 2.698 0.5 - 537.5 1 2 0 0.0018 15 0 0 0 1.59E+07 1.23E+07 - - - 5.1736 0.7939 221125_WJC_METTL3_EV_vs_WT_F01.19377.19377.2 0.0328 22-Jul K.TLVLSNLSYSAT.E "sp|P19338|NUCL_HUMAN,tr|A0A7I2V506|A0A7I2V506_HUMAN,tr|A0A7I2V699|A0A7I2V699_HUMAN,tr|A0A7I2V2U7|A0A7I2V2U7_HUMAN,tr|A0A7I2V3F3|A0A7I2V3F3_HUMAN,tr|A0A7I2V428|A0A7I2V428_HUMAN,tr|A0A7I2V349|A0A7I2V349_HUMAN,tr|H7BY16|H7BY16_HUMAN,tr|A0A7I2V5M5|A0A7I2V5M5_HUMAN,tr|C9JLB1|C9JLB1_HUMAN" 10 1267.666 - 6922 19377 2 1267.666151 634.8403 Nucleolin OS=Homo sapiens OX=9606 GN=NCL PE=1 SV=3 5.18 3655.5 - 1.28E+06 - - - 0.1325 - 1.189 0.233 - 131 1 1 0 0.0002 12 0 0 0 - - - - - 1.2174 0.999 221125_WJC_METTL3_EV_vs_WT_F01.19378.19378.2 7.18E-05 18-Dec R.IINDLLQSLR.S "sp|Q92945|FUBP2_HUMAN,tr|M0R0C6|M0R0C6_HUMAN,tr|A0A087WTP3|A0A087WTP3_HUMAN" 3 1183.6925 1.23 6923 19378 2 1183.693409 592.8535 Far upstream element-binding protein 2 OS=Homo sapiens OX=9606 GN=KHSRP PE=1 SV=4 5.84 3655.5 - 6.76E+06 - - - 0.7916 - 2.373 0.153 - 463.7 1 2 0 0.0009 10 0 0 0 1.07E+08 8.71E+07 - - - 2.5829 0.9991 221125_WJC_METTL3_EV_vs_WT_F01.19379.19379.2 4.31 18-Oct R.IINDLLQSLR[166.11].S "sp|Q92945|FUBP2_HUMAN,tr|M0R0C6|M0R0C6_HUMAN,tr|A0A087WTP3|A0A087WTP3_HUMAN" 3 1193.7007 1.23 6924 19379 2 1193.701311 597.8576 Far upstream element-binding protein 2 OS=Homo sapiens OX=9606 GN=KHSRP PE=1 SV=4 5.84 3655.6 - 6.06E+06 - - - 0.4767 - 2.128 0.182 - 256.1 1 2 0 0.0006 10 0 0 0 1.07E+08 8.71E+07 - - - 2.493 1 221125_WJC_METTL3_EV_vs_WT_F01.19380.19380.2 1.68E-05 16/26 K.LLDAVDTYIPVPAR.D sp|P49411|EFTU_HUMAN 1 1541.8453 1.6 6925 19380 2 1541.846296 771.9299 "Elongation factor Tu, mitochondrial OS=Homo sapiens OX=9606 GN=TUFM PE=1 SV=2" 4.21 3655.6 - 5.85E+06 - - - 0.6174 - 3.104 0.524 - 965.8 1 2 0 0.001 14 0 0 0 1.99E+08 1.25E+08 - - - 5.7534 0.9933 221125_WJC_METTL3_EV_vs_WT_F01.19383.19383.2 0.201 16-Jul K.LFSNVLILK.S "sp|Q86UP3|ZFHX4_HUMAN,tr|E7EVZ1|E7EVZ1_HUMAN" 2 1045.6536 1.64 6928 19383 2 1045.654698 523.8341 Zinc finger homeobox protein 4 OS=Homo sapiens OX=9606 GN=ZFHX4 PE=1 SV=1 8.75 3655.8 - 2.27E+06 - - - 1.0807 - 1.309 0.176 - 88 1 2 0 0.0011 9 0 0 0 8.97E+06 5.46E+06 - - - 1.1196 0.999 221125_WJC_METTL3_EV_vs_WT_F01.19385.19385.2 0.00623 16-Sep K.LFSNVLILK[136.11].S "sp|Q86UP3|ZFHX4_HUMAN,tr|E7EVZ1|E7EVZ1_HUMAN" 2 1053.6678 1.64 6930 19385 2 1053.667971 527.8412 Zinc finger homeobox protein 4 OS=Homo sapiens OX=9606 GN=ZFHX4 PE=1 SV=1 8.75 3655.9 - 1.69E+06 - - - 0.1927 - 1.543 0.279 - 162.4 1 2 0 0.0002 9 0 0 0 8.97E+06 5.46E+06 - - - 2.3564 0.996 221125_WJC_METTL3_EV_vs_WT_F01.19387.19387.3 0.0223 Sep-40 R.LLESLDQLELR[166.11].V sp|O95816|BAG2_HUMAN 1 1337.743 0.25 6932 19387 3 1337.743452 446.9216 BAG family molecular chaperone regulator 2 OS=Homo sapiens OX=9606 GN=BAG2 PE=1 SV=1 4.14 3656.1 - 948917 - - - 0.3371 - 1.888 0.182 - 172.7 1 2 0 0.0005 11 0 0 0 1.06E+06 4.33E+06 - - - 2.3744 0.9999 221125_WJC_METTL3_EV_vs_WT_F01.19389.19389.2 1.33E-05 14/26 R.LIVVLEGASLETVK.V "sp|Q92979|NEP1_HUMAN,tr|V9GYP5|V9GYP5_HUMAN,tr|A0A087WWQ2|A0A087WWQ2_HUMAN" 3 1469.8705 -1 6934 19389 2 1469.872216 735.9425 Ribosomal RNA small subunit methyltransferase NEP1 OS=Homo sapiens OX=9606 GN=EMG1 PE=1 SV=4 4.53 3656.4 - 885062 - - - 1.1702 - 2.787 0.521 - 604.4 1 2 0 0.0017 14 0 0 0 0.00E+00 0.00E+00 - - - 5.4607 0.9988 221125_WJC_METTL3_EV_vs_WT_F01.19390.19390.2 0.955 16-Sep R.VLLPVLLNK.N sp|O00186|STXB3_HUMAN 1 1007.6743 1.26 6935 19390 2 1007.674648 504.8444 Syntaxin-binding protein 3 OS=Homo sapiens OX=9606 GN=STXBP3 PE=1 SV=2 8.72 3656.5 - 817780 - - - 0.3424 - 1.743 0.215 - 209.7 1 2 0 0.0003 9 0 0 0 5.24E+06 4.17E+06 - - - 2.2363 0.9998 221125_WJC_METTL3_EV_vs_WT_F01.19391.19391.2 1.33E-05 22-Nov K.VLLSPDYLPAMR[166.11].R sp|Q7Z6Z7|HUWE1_HUMAN 1 1383.746 0.42 6936 19391 2 1383.747662 692.8803 E3 ubiquitin-protein ligase HUWE1 OS=Homo sapiens OX=9606 GN=HUWE1 PE=1 SV=3 5.81 3656.6 - 645412 - - - 1.217 - 2.281 0.46 - 446.2 1 2 0 0.0017 12 0 0 0 1.83E+06 4.38E+06 - - - 4.6077 0.9108 221125_WJC_METTL3_EV_vs_WT_F01.19393.19393.2 7.21 26-May R.NC[160.03]SSLPGLIGNDIK.S "sp|Q969S9|RRF2M_HUMAN,tr|D6RAL1|D6RAL1_HUMAN" 2 1486.745 -1 6938 19393 2 1486.745767 744.3798 "Ribosome-releasing factor 2, mitochondrial OS=Homo sapiens OX=9606 GN=GFM2 PE=1 SV=1" 5.83 3656.8 - 461910 - - - 0.53 - 1.205 0.024 - 44.3 10 2 0 0.0008 14 0 0 0 0.00E+00 0.00E+00 - - - -0.7607 0.9999 221125_WJC_METTL3_EV_vs_WT_F01.19397.19397.2 2.75E-06 22-Nov R.ELYLEDSPLELK[136.11].L sp|Q8TEM1|PO210_HUMAN 1 1455.7588 1.71 6941 19397 2 1455.759265 728.8867 Nuclear pore membrane glycoprotein 210 OS=Homo sapiens OX=9606 GN=NUP210 PE=1 SV=3 4 3657.3 - 622932 - - - 0.3009 - 2.253 0.472 - 353.6 1 2 0 0.0004 12 0 0 0 1.66E+07 9.75E+06 - - - 4.6643 1 221125_WJC_METTL3_EV_vs_WT_F01.19399.19399.2 2.04E-05 15/26 K.LLDAVDTYIPVPAR[166.11].D sp|P49411|EFTU_HUMAN 1 1551.8536 1.6 6943 19399 2 1551.852794 776.9341 "Elongation factor Tu, mitochondrial OS=Homo sapiens OX=9606 GN=TUFM PE=1 SV=2" 4.21 3657.4 - 1.52E+07 - - - -0.5284 - 2.774 0.56 - 773.7 1 2 0 -0.0008 14 0 0 0 1.99E+08 1.25E+08 - - - 5.7373 0.9999 221125_WJC_METTL3_EV_vs_WT_F01.19400.19400.3 0.00258 14/52 K.LLDAVDTYIPVPAR[166.11].D sp|P49411|EFTU_HUMAN 1 1551.8536 1.61 6944 19400 3 1551.853545 518.2918 "Elongation factor Tu, mitochondrial OS=Homo sapiens OX=9606 GN=TUFM PE=1 SV=2" 4.21 3657.5 - 3.56E+06 - - - -0.0445 - 2.847 0.389 - 189.8 1 2 0 -0.0001 14 0 0 0 4.20E+07 2.61E+07 - - - 5.6574 0.9994 221125_WJC_METTL3_EV_vs_WT_F01.19403.19403.2 0.00713 14-Aug R.NLFEQLVR.R "sp|Q9H0H5|RGAP1_HUMAN,tr|F8VV47|F8VV47_HUMAN,tr|F8VUW9|F8VUW9_HUMAN,tr|F8VWY4|F8VWY4_HUMAN,tr|F8VRD2|F8VRD2_HUMAN,tr|F8VVY0|F8VVY0_HUMAN,tr|F8VZ66|F8VZ66_HUMAN,tr|F8VWX0|F8VWX0_HUMAN,tr|F8VS54|F8VS54_HUMAN,tr|F8W0L1|F8W0L1_HUMAN,tr|F8VVE5|F8VVE5_HUMAN,tr|F8VV39|F8VV39_HUMAN,tr|F8VXH1|F8VXH1_HUMAN" 13 1017.5607 1.2 6947 19403 2 1017.560816 509.7876 Rac GTPase-activating protein 1 OS=Homo sapiens OX=9606 GN=RACGAP1 PE=1 SV=1 6 3657.6 - 1.93E+06 - - - 0.0845 - 1.474 0.357 - 238.1 1 2 0 0.0001 8 0 0 0 8.27E+06 6.87E+06 - - - 2.8479 0.9932 221125_WJC_METTL3_EV_vs_WT_F01.19406.19406.2 0.246 18-Jun R.LIPDDLSLLK[136.11].L sp|Q8NCF5|NF2IP_HUMAN 1 1133.6787 0.82 6950 19406 2 1133.678142 567.8466 NFATC2-interacting protein OS=Homo sapiens OX=9606 GN=NFATC2IP PE=1 SV=1 4.21 3658 - 645033 - - - -0.5151 - 1.202 0.219 - 55.3 4 2 0 -0.0006 10 0 0 0 9.84E+06 1.20E+07 - - - 0.903 1 221125_WJC_METTL3_EV_vs_WT_F01.19408.19408.2 1.48E-07 14/26 R.WTTEEQLLAVQAIR.K sp|Q9UKL0|RCOR1_HUMAN 1 1656.8835 1.82 6952 19408 2 1656.883924 829.449 REST corepressor 1 OS=Homo sapiens OX=9606 GN=RCOR1 PE=1 SV=2 4.53 3658.2 - 397028 - - - 0.2432 - 2.803 0.588 - 767.3 1 2 0 0.0004 14 0 0 0 1.87E+06 1.02E+06 - - - 5.9703 0.9998 221125_WJC_METTL3_EV_vs_WT_F01.19417.19417.2 0.00594 18-Nov K.GTAAILEYLR[166.11].D sp|Q9H9A6|LRC40_HUMAN 1 1115.6214 2.45 6959 19417 2 1115.620435 558.818 Leucine-rich repeat-containing protein 40 OS=Homo sapiens OX=9606 GN=LRRC40 PE=1 SV=1 6 3659.3 - 1.70E+06 - - - -0.891 - 2.238 0.378 - 532.9 1 2 0 -0.001 10 0 0 0 1.89E+07 7.73E+06 - - - 4.0812 0.9993 221125_WJC_METTL3_EV_vs_WT_F01.19418.19418.3 6.63E-05 13/52 K.LLDAVDTYIPVPAR.D sp|P49411|EFTU_HUMAN 1 1541.8453 1.61 6960 19418 3 1541.845989 514.9557 "Elongation factor Tu, mitochondrial OS=Homo sapiens OX=9606 GN=TUFM PE=1 SV=2" 4.21 3659.4 - 9.96E+06 - - - 0.4183 - 2.349 0.244 - 155.4 1 2 0 0.0006 14 0 0 0 4.20E+07 2.61E+07 - - - 3.5297 0.9997 221125_WJC_METTL3_EV_vs_WT_F01.19419.19419.2 0.00539 16-Sep K.ALEVYDLIR.T "sp|Q9H5X1|CIA2A_HUMAN,tr|H0YKV4|H0YKV4_HUMAN" 2 1090.6023 1.25 6961 19419 2 1090.602788 546.3084 Cytosolic iron-sulfur assembly component 2A OS=Homo sapiens OX=9606 GN=CIAO2A PE=1 SV=1 4.37 3659.4 - 1.80E+06 - - - 0.4841 - 1.94 0.346 - 325.8 1 2 0 0.0005 9 0 0 0 1.26E+07 1.00E+07 - - - 3.5136 0.9996 221125_WJC_METTL3_EV_vs_WT_F01.19421.19421.2 0.00504 16-Aug K.VIPTLALLK.D sp|O14530|TXND9_HUMAN 1 966.6478 2.27 6963 19421 2 966.647604 484.3312 Thioredoxin domain-containing protein 9 OS=Homo sapiens OX=9606 GN=TXNDC9 PE=1 SV=2 8.72 3659.6 - 1.52E+06 - - - -0.1552 - 1.468 0.405 - 163.9 1 2 0 -0.0001 9 0 0 0 9.62E+06 4.23E+06 - - - 3.1429 0.9999 221125_WJC_METTL3_EV_vs_WT_F01.19422.19422.2 6.16E-05 13/22 K.ILVVNAAYFVGK.W sp|P36952|SPB5_HUMAN 1 1292.7493 999 6964 19422 2 1292.748616 647.3819 Serpin B5 OS=Homo sapiens OX=9606 GN=SERPINB5 PE=1 SV=2 8.59 3659.7 - 1.19E+06 - - - -0.4974 - 2.176 0.506 - 466.3 1 2 0 -0.0006 12 0 0 0 5.01E+06 0.00E+00 - - - 4.8238 0.9953 221125_WJC_METTL3_EV_vs_WT_F01.19423.19423.2 1.41 20-Aug R.ALLLSEPSLLR.T "sp|Q9BTP7|FAP24_HUMAN,tr|K7EKQ4|K7EKQ4_HUMAN" 2 1210.7285 1.08 6965 19423 2 1210.731738 606.3715 Fanconi anemia core complex-associated protein 24 OS=Homo sapiens OX=9606 GN=FAAP24 PE=1 SV=2 6.05 3659.7 - 1.18E+06 - - - 2.6546 - 1.787 0.206 - 187.9 1 2 0 0.0032 11 0 0 0 5.19E+06 4.79E+06 - - - 2.132 0.9998 221125_WJC_METTL3_EV_vs_WT_F01.19425.19425.2 0.0122 18-Nov K.ELVLLLDEER[166.11].A sp|A6NKD9|CC85C_HUMAN 1 1237.6793 3.2 6967 19425 2 1237.67968 619.8469 Coiled-coil domain-containing protein 85C OS=Homo sapiens OX=9606 GN=CCDC85C PE=1 SV=1 4 3659.9 - 1.06E+06 - - - 0.2763 - 2.432 0.365 - 608.6 1 2 0 0.0003 10 0 0 0 1.66E+07 5.18E+06 - - - 4.2175 0.9999 221125_WJC_METTL3_EV_vs_WT_F01.19426.19426.2 7.19E-05 18-Oct R.C[160.03]LFQSPLFAK[136.11].A sp|Q86X55|CARM1_HUMAN 1 1217.6358 0.31 6968 19426 2 1217.63495 609.8252 Histone-arginine methyltransferase CARM1 OS=Homo sapiens OX=9606 GN=CARM1 PE=1 SV=3 8.22 3660 - 966721 - - - -0.7112 - 1.794 0.536 - 270 1 2 0 -0.0009 10 0 0 0 1.84E+06 5.85E+06 - - - 4.631 0.9979 221125_WJC_METTL3_EV_vs_WT_F01.19427.19427.2 0.168 16-Aug K.VIPTLALLK[136.11].D sp|O14530|TXND9_HUMAN 1 974.662 2.27 6969 19427 2 974.661477 488.3383 Thioredoxin domain-containing protein 9 OS=Homo sapiens OX=9606 GN=TXNDC9 PE=1 SV=2 8.72 3660.1 - 838814 - - - -0.4894 - 1.489 0.213 - 166.9 1 2 0 -0.0005 9 0 0 0 9.62E+06 4.23E+06 - - - 1.7658 0.9976 221125_WJC_METTL3_EV_vs_WT_F01.19434.19434.2 1 22-Nov K.IAILDIEPQTLK[136.11].L sp|Q00013|EM55_HUMAN 1 1360.8057 0.26 6976 19434 2 1360.804152 681.4101 55 kDa erythrocyte membrane protein OS=Homo sapiens OX=9606 GN=MPP1 PE=1 SV=2 4.37 3661 - 419598 - - - -1.1508 - 2.068 0.122 - 372.6 1 2 0 -0.0016 12 0 0 0 6.87E+05 2.64E+06 - - - 1.8534 0.9998 221125_WJC_METTL3_EV_vs_WT_F01.19437.19437.2 0.0131 18-Nov K.ELVLLLDEER.A sp|A6NKD9|CC85C_HUMAN 1 1227.6711 3.04 6978 19437 2 1227.670892 614.8428 Coiled-coil domain-containing protein 85C OS=Homo sapiens OX=9606 GN=CCDC85C PE=1 SV=1 4 3661.4 - 2.55E+06 - - - -0.1434 - 2.449 0.378 - 733.7 1 2 0 -0.0002 10 0 0 0 1.57E+07 5.18E+06 - - - 4.333 0.9999 221125_WJC_METTL3_EV_vs_WT_F01.19438.19438.2 0.000202 18-Oct K.EAFVVEEWVK[136.11].E "sp|P35606|COPB2_HUMAN,tr|H0Y938|H0Y938_HUMAN,tr|A0A7I2V258|A0A7I2V258_HUMAN,tr|H0YAC7|H0YAC7_HUMAN" 4 1242.6376 0.6 6979 19438 2 1242.637926 622.3261 Coatomer subunit beta' OS=Homo sapiens OX=9606 GN=COPB2 PE=1 SV=2 4.25 3661.5 - 1.29E+06 - - - 0.2704 - 2.121 0.475 - 336.8 1 2 0 0.0003 10 0 0 0 4.53E+06 7.56E+06 - - - 4.648 0.9992 221125_WJC_METTL3_EV_vs_WT_F01.19439.19439.2 0.00271 14-Aug R.NIPMLFVR[166.11].G sp|P62310|LSM3_HUMAN 1 998.5611 2.46 6980 19439 2 998.561245 500.2878 U6 snRNA-associated Sm-like protein LSm3 OS=Homo sapiens OX=9606 GN=LSM3 PE=1 SV=2 9.75 3661.6 - 1.72E+06 - - - 0.1672 - 1.402 0.337 - 244.4 1 2 0 0.0002 8 0 0 0 5.04E+07 2.05E+07 - - - 2.5491 0.9999 221125_WJC_METTL3_EV_vs_WT_F01.19440.19440.2 0.00823 14/22 K.DAGVIAGLNVLR[166.11].L "sp|P0DMV8|HS71A_HUMAN,sp|P34931|HS71L_HUMAN,sp|P0DMV9|HS71B_HUMAN,tr|Q53FA3|Q53FA3_HUMAN,tr|A0A0G2JIW1|A0A0G2JIW1_HUMAN" 5 1206.696 0.001 6981 19440 2 1206.69686 604.3553 Heat shock 70 kDa protein 1A OS=Homo sapiens OX=9606 GN=HSPA1A PE=1 SV=1 5.84 3661.7 - 1.28E+06 - - - 0.7201 - 2.649 0.432 - 744.7 1 2 0 0.0009 12 0 0 0 0.00E+00 2.77E+07 - - - 4.7947 0.999 221125_WJC_METTL3_EV_vs_WT_F01.19441.19441.2 0.0181 18-Aug K.EAFVVEEWVK.E "sp|P35606|COPB2_HUMAN,tr|H0Y938|H0Y938_HUMAN,tr|A0A7I2V258|A0A7I2V258_HUMAN,tr|H0YAC7|H0YAC7_HUMAN" 4 1234.6234 0.6 6982 19441 2 1234.622354 618.319 Coatomer subunit beta' OS=Homo sapiens OX=9606 GN=COPB2 PE=1 SV=2 4.25 3661.8 - 1.10E+06 - - - -0.8391 - 1.613 0.279 - 191.4 1 2 0 -0.001 10 0 0 0 4.53E+06 7.56E+06 - - - 2.4359 0.9997 221125_WJC_METTL3_EV_vs_WT_F01.19446.19446.2 6.13E-06 22-Dec K.QYPISLVLAPTR.E "sp|O00571|DDX3X_HUMAN,sp|O15523|DDX3Y_HUMAN,tr|A0A2R8YFR4|A0A2R8YFR4_HUMAN,tr|A0A2R8YCW1|A0A2R8YCW1_HUMAN,tr|A0A2R8YDH3|A0A2R8YDH3_HUMAN,tr|A0A2R8YDT5|A0A2R8YDT5_HUMAN,tr|A0A2R8Y645|A0A2R8Y645_HUMAN,tr|A0A2R8YF78|A0A2R8YF78_HUMAN,tr|A0A0D9SFB3|A0A0D9SFB3_HUMAN,tr|A0A2R8YFS5|A0A2R8YFS5_HUMAN,tr|A0A0D9SF53|A0A0D9SF53_HUMAN,tr|A0A2R8Y5G6|A0A2R8Y5G6_HUMAN,tr|A0A2R8Y7T2|A0A2R8Y7T2_HUMAN,tr|A0A0D9SG12|A0A0D9SG12_HUMAN,tr|A0A2U3TZJ9|A0A2U3TZJ9_HUMAN,tr|A0A2R8Y4A4|A0A2R8Y4A4_HUMAN" 16 1356.7765 1.41 6987 19446 2 1356.778592 679.3955 ATP-dependent RNA helicase DDX3X OS=Homo sapiens OX=9606 GN=DDX3X PE=1 SV=3 8.75 3662.4 - 503564 - - - 1.5154 - 2.08 0.432 - 438.2 1 2 0 0.0021 12 0 0 0 1.51E+07 1.07E+07 - - - 4.1581 1 221125_WJC_METTL3_EV_vs_WT_F01.19447.19447.2 6.89E-09 22-Dec K.QYPISLVLAPTR[166.11].E "sp|O00571|DDX3X_HUMAN,sp|O15523|DDX3Y_HUMAN,tr|A0A2R8YFR4|A0A2R8YFR4_HUMAN,tr|A0A2R8YCW1|A0A2R8YCW1_HUMAN,tr|A0A2R8YDH3|A0A2R8YDH3_HUMAN,tr|A0A2R8YDT5|A0A2R8YDT5_HUMAN,tr|A0A2R8Y645|A0A2R8Y645_HUMAN,tr|A0A2R8YF78|A0A2R8YF78_HUMAN,tr|A0A0D9SFB3|A0A0D9SFB3_HUMAN,tr|A0A2R8YFS5|A0A2R8YFS5_HUMAN,tr|A0A0D9SF53|A0A0D9SF53_HUMAN,tr|A0A2R8Y5G6|A0A2R8Y5G6_HUMAN,tr|A0A2R8Y7T2|A0A2R8Y7T2_HUMAN,tr|A0A0D9SG12|A0A0D9SG12_HUMAN,tr|A0A2U3TZJ9|A0A2U3TZJ9_HUMAN,tr|A0A2R8Y4A4|A0A2R8Y4A4_HUMAN" 16 1366.7848 1.41 6988 19447 2 1366.78335 684.3997 ATP-dependent RNA helicase DDX3X OS=Homo sapiens OX=9606 GN=DDX3X PE=1 SV=3 8.75 3662.5 - 444746 - - - -1.0653 - 2.336 0.632 - 508.6 1 2 0 -0.0015 12 0 0 0 1.51E+07 1.07E+07 - - - 5.9409 0.9791 221125_WJC_METTL3_EV_vs_WT_F01.19450.19450.2 0.374 20-Jul K.LFQLPTPPLSR.H "sp|Q9Y6K0|CEPT1_HUMAN,tr|A0A0C4DGS9|A0A0C4DGS9_HUMAN" 2 1267.7289 1 6991 19450 2 1267.726894 634.8717 Choline\ethanolaminephosphotransferase 1 OS=Homo sapiens OX=9606 GN=CEPT1 PE=1 SV=1 9.75 3662.9 - 272806 - - - -1.5492 - 1.418 0.061 - 137 1 2 0 -0.002 11 0 0 0 2.59E+06 2.58E+06 - - - 0.4357 0.9999 221125_WJC_METTL3_EV_vs_WT_F01.19453.19453.2 2.51E-06 26-Sep K.LISWYDNEFGYSNR[166.11].V "sp|P04406|G3P_HUMAN,tr|E7EUT5|E7EUT5_HUMAN" 2 1772.8034 -1 6994 19453 2 1772.80559 887.409 Glyceraldehyde-3-phosphate dehydrogenase OS=Homo sapiens OX=9606 GN=GAPDH PE=1 SV=3 4.37 3663.3 - 235083 - - - 1.2523 - 2.087 0.631 - 195.5 1 2 0 0.0022 14 0 0 0 0.00E+00 0.00E+00 - - - 5.5471 0.9992 221125_WJC_METTL3_EV_vs_WT_F01.19455.19455.2 0.114 20-Sep R.LPAYLTIQMVR.F "sp|P54578|UBP14_HUMAN,tr|A6NJA2|A6NJA2_HUMAN" 2 1303.7322 -1 6996 19455 2 1303.731271 652.8734 Ubiquitin carboxyl-terminal hydrolase 14 OS=Homo sapiens OX=9606 GN=USP14 PE=1 SV=3 8.75 3663.5 - 202597 - - - -0.7348 - 1.77 0.285 - 282.1 1 2 0 -0.001 11 0 0 0 0.00E+00 0.00E+00 - - - 2.6903 0.9996 221125_WJC_METTL3_EV_vs_WT_F01.19462.19462.2 5.00E-10 17/24 R.GAAGALLVYDITR.R "sp|P61019|RAB2A_HUMAN,sp|Q8WUD1|RAB2B_HUMAN,tr|A0A3B3ITL1|A0A3B3ITL1_HUMAN,tr|Q6PIK3|Q6PIK3_HUMAN,tr|E9PKL7|E9PKL7_HUMAN" 5 1318.7245 0.76 7002 19462 2 1318.726588 660.3695 Ras-related protein Rab-2A OS=Homo sapiens OX=9606 GN=RAB2A PE=1 SV=1 5.84 3664.1 - 2.77E+06 - - - 1.5826 - 3.688 0.231 - 1391.3 1 2 0 0.0021 13 0 0 0 4.91E+07 6.50E+07 - - - 4.096 0.9995 221125_WJC_METTL3_EV_vs_WT_F01.19463.19463.2 0.00155 18-Aug K.DLQEVIELTK.D sp|O75940|SPF30_HUMAN 1 1186.6445 0.81 7003 19463 2 1186.644888 594.3295 Survival of motor neuron-related-splicing factor 30 OS=Homo sapiens OX=9606 GN=SMNDC1 PE=1 SV=1 4.14 3664.2 - 2.71E+06 - - - 0.311 - 1.763 0.338 - 181.8 1 2 0 0.0004 10 0 0 0 1.19E+07 1.47E+07 - - - 3.1201 0.9992 221125_WJC_METTL3_EV_vs_WT_F01.19465.19465.2 0.0199 16-Sep K.LQLSLADFR.R "sp|O00541|PESC_HUMAN,tr|B5MCF9|B5MCF9_HUMAN" 2 1061.5869 0.71 7005 19465 2 1061.588411 531.8007 Pescadillo homolog OS=Homo sapiens OX=9606 GN=PES1 PE=1 SV=1 5.84 3664.3 - 1.57E+06 - - - 1.381 - 2.075 0.261 - 280.9 1 2 0 0.0015 9 0 0 0 7.39E+06 1.04E+07 - - - 3.0801 0.9994 221125_WJC_METTL3_EV_vs_WT_F01.19466.19466.2 0.00152 16-Oct R.YLDVSILGK[136.11].F sp|Q86U44|MTA70_HUMAN 1 1014.5841 0.5 7006 19466 2 1014.58602 508.2993 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 5.83 3664.4 - 1.36E+06 - - - 1.8944 - 1.866 0.386 - 240 1 2 0 0.0019 9 0 0 0 4.88E+06 9.73E+06 - - - 3.6961 0.9999 221125_WJC_METTL3_EV_vs_WT_F01.19467.19467.2 3.93E-05 14/22 R.TVQIAAVVDVIR.E sp|P12273|PIP_HUMAN 1 1282.7609 999 7007 19467 2 1282.761135 642.3877 Prolactin-inducible protein OS=Homo sapiens OX=9606 GN=PIP PE=1 SV=1 5.5 3664.5 - 1.06E+06 - - - 0.1941 - 2.739 0.496 - 809 1 2 0 0.0002 12 0 0 0 5.10E+06 0.00E+00 - - - 5.3555 0.9931 221125_WJC_METTL3_EV_vs_WT_F01.19472.19472.2 2.83E-06 26-Dec R.VETGVLK[136.11]PGMVVTF.A "sp|P68104|EF1A1_HUMAN,sp|Q5VTE0|EF1A3_HUMAN,tr|A0A7I2V659|A0A7I2V659_HUMAN,tr|A0A7I2V3H3|A0A7I2V3H3_HUMAN,tr|A0A7I2V5N4|A0A7I2V5N4_HUMAN,tr|A0A087WVQ9|A0A087WVQ9_HUMAN" 6 1483.82 0.31 7012 19472 2 1483.820923 742.9173 Elongation factor 1-alpha 1 OS=Homo sapiens OX=9606 GN=EEF1A1 PE=1 SV=1 5.97 3665.1 - 646355 - - - 0.6301 - 2.542 0.514 - 405 1 1 0 0.0009 14 0 0 0 1.56E+06 4.98E+06 - - - 5.1783 0.9999 221125_WJC_METTL3_EV_vs_WT_F01.19475.19475.2 2.25E-06 22-Sep K.YGLEGTVFFEEK[136.11].D "sp|Q9Y2L1|RRP44_HUMAN,tr|G3V1J5|G3V1J5_HUMAN" 2 1425.6907 1.89 7015 19475 2 1425.691549 713.8527 Exosome complex exonuclease RRP44 OS=Homo sapiens OX=9606 GN=DIS3 PE=1 SV=2 4.25 3665.5 - 395825 - - - 0.5618 - 2.004 0.517 - 218.8 1 2 0 0.0008 12 0 0 0 2.60E+06 1.38E+06 - - - 4.6884 0.9997 221125_WJC_METTL3_EV_vs_WT_F01.19476.19476.2 1.01E-05 22-Dec K.YGLEGTVFFEEK.D "sp|Q9Y2L1|RRP44_HUMAN,tr|G3V1J5|G3V1J5_HUMAN" 2 1417.6765 1.82 7016 19476 2 1417.680003 709.8456 Exosome complex exonuclease RRP44 OS=Homo sapiens OX=9606 GN=DIS3 PE=1 SV=2 4.25 3665.6 - 388009 - - - 2.4371 - 2.568 0.56 - 475.3 1 2 0 0.0035 12 0 0 0 2.51E+06 1.38E+06 - - - 5.6576 0.9996 221125_WJC_METTL3_EV_vs_WT_F01.19479.19479.2 0.0267 16-Sep K.LQLSLADFR[166.11].R "sp|O00541|PESC_HUMAN,tr|B5MCF9|B5MCF9_HUMAN" 2 1071.5952 0.71 7018 19479 2 1071.596115 536.8049 Pescadillo homolog OS=Homo sapiens OX=9606 GN=PES1 PE=1 SV=1 5.84 3666 - 2.45E+06 - - - 0.8399 - 2.009 0.312 - 284.3 1 2 0 0.0009 9 0 0 0 7.39E+06 1.04E+07 - - - 3.3635 0.9103 221125_WJC_METTL3_EV_vs_WT_F01.19481.19481.2 0.0553 18-Aug K.ALANVNIGSL.L sp|P05386|RLA1_HUMAN 1 970.5447 - 7020 19481 2 970.544584 486.2796 60S acidic ribosomal protein P1 OS=Homo sapiens OX=9606 GN=RPLP1 PE=1 SV=1 5.57 3666.2 - 3.35E+06 - - - -0.1659 - 1.439 0.256 - 123.4 1 1 0 -0.0002 10 0 0 0 - - - - - 1.9477 0.9998 221125_WJC_METTL3_EV_vs_WT_F01.19483.19483.2 0.00239 18-Sep K.SVLIGEFLEK.V "sp|O43148|MCES_HUMAN,tr|K7EP06|K7EP06_HUMAN" 2 1133.6332 0.96 7022 19483 2 1133.632401 567.8239 mRNA cap guanine-N7 methyltransferase OS=Homo sapiens OX=9606 GN=RNMT PE=1 SV=1 4.53 3666.3 - 1.75E+06 - - - -0.7277 - 1.812 0.455 - 275.3 1 2 0 -0.0008 10 0 0 0 9.66E+07 1.00E+08 - - - 4.0606 1 221125_WJC_METTL3_EV_vs_WT_F01.19484.19484.2 4.06E-09 13/26 R.IMGIPEEEQMGLLR[166.11].V sp|P35579|MYH9_HUMAN 1 1624.8192 0.88 7023 19484 2 1624.821048 813.4169 Myosin-9 OS=Homo sapiens OX=9606 GN=MYH9 PE=1 SV=4 4.25 3666.4 - 1.08E+06 - - - 1.1257 - 2.643 0.62 - 444.7 1 2 0 0.0018 14 0 0 0 3.31E+07 3.77E+07 - - - 6.0587 1 221125_WJC_METTL3_EV_vs_WT_F01.19486.19486.2 1.74E-09 13/22 R.TMGVMFTPLTVK.Y "sp|O00303|EIF3F_HUMAN,tr|H0YDT6|H0YDT6_HUMAN" 2 1323.6931 1.18 7025 19486 2 1323.694741 662.8538 Eukaryotic translation initiation factor 3 subunit F OS=Homo sapiens OX=9606 GN=EIF3F PE=1 SV=1 8.41 3666.7 - 973795 - - - 1.2654 - 2.409 0.645 - 583 1 2 0 0.0017 12 0 0 0 1.08E+07 9.16E+06 - - - 6.1178 0.9863 221125_WJC_METTL3_EV_vs_WT_F01.19487.19487.3 4.11E-06 14/48 R.GAAGALLVYDITR[166.11].R "sp|P61019|RAB2A_HUMAN,sp|Q8WUD1|RAB2B_HUMAN,tr|A0A3B3ITL1|A0A3B3ITL1_HUMAN,tr|Q6PIK3|Q6PIK3_HUMAN,tr|E9PKL7|E9PKL7_HUMAN" 5 1328.7328 1.15 7026 19487 3 1328.733279 443.9182 Ras-related protein Rab-2A OS=Homo sapiens OX=9606 GN=RAB2A PE=1 SV=1 5.84 3666.8 - 961941 - - - 0.3823 - 2.638 0.04 - 354.9 1 2 0 0.0005 13 0 0 0 7.16E+06 6.25E+06 - - - 1.6158 0.8794 221125_WJC_METTL3_EV_vs_WT_F01.19488.19488.2 0.0138 22-Jun N.NDGNAPSFGLLR[166.11].S sp|Q06190|P2R3A_HUMAN 1 1269.6341 0.86 7027 19488 2 1269.635123 635.8243 Serine\threonine-protein phosphatase 2A regulatory subunit B'' subunit alpha OS=Homo sapiens OX=9606 GN=PPP2R3A PE=1 SV=1 5.84 3667 - 957771 - - - 0.7908 - 1.251 0.299 - 79.9 1 1 0 0.001 12 0 0 0 5.34E+06 6.19E+06 - - - 1.8383 0.9999 221125_WJC_METTL3_EV_vs_WT_F01.19502.19502.2 8.32E-05 18-Nov R.LGLEDFESLK.V sp|Q15208|STK38_HUMAN 1 1149.5918 3.5 7040 19502 2 1149.591236 575.8032 Serine\threonine-protein kinase 38 OS=Homo sapiens OX=9606 GN=STK38 PE=1 SV=1 4.14 3668.5 - 1.18E+07 - - - -0.4515 - 2.366 0.507 - 323.6 1 2 0 -0.0005 10 0 0 0 1.49E+09 4.26E+08 - - - 5.1894 0.9999 221125_WJC_METTL3_EV_vs_WT_F01.19503.19503.2 0.000121 18-Nov K.LLDEVFFSEK.L "sp|P25789|PSA4_HUMAN,tr|H0YKT8|H0YKT8_HUMAN,tr|H0YMI6|H0YMI6_HUMAN,tr|H0YLS6|H0YLS6_HUMAN,tr|H0YMA1|H0YMA1_HUMAN,tr|H0YLC2|H0YLC2_HUMAN,tr|H0YL69|H0YL69_HUMAN,tr|H0YN18|H0YN18_HUMAN,tr|H0YMZ1|H0YMZ1_HUMAN" 9 1225.6231 1.24 7041 19503 2 1225.622982 613.8188 Proteasome subunit alpha type-4 OS=Homo sapiens OX=9606 GN=PSMA4 PE=1 SV=1 4.14 3668.5 - 5.34E+06 - - - -0.0596 - 2.289 0.477 - 340.3 1 2 0 -0.0001 10 0 0 0 1.29E+08 1.04E+08 - - - 4.8756 0.9999 221125_WJC_METTL3_EV_vs_WT_F01.19504.19504.2 2.12E-05 18-Oct K.LLDEVFFSEK[136.11].L "sp|P25789|PSA4_HUMAN,tr|H0YKT8|H0YKT8_HUMAN,tr|H0YMI6|H0YMI6_HUMAN,tr|H0YLS6|H0YLS6_HUMAN,tr|H0YMA1|H0YMA1_HUMAN,tr|H0YLC2|H0YLC2_HUMAN,tr|H0YL69|H0YL69_HUMAN,tr|H0YN18|H0YN18_HUMAN,tr|H0YMZ1|H0YMZ1_HUMAN" 9 1233.6373 1.24 7042 19504 2 1233.637392 617.8259 Proteasome subunit alpha type-4 OS=Homo sapiens OX=9606 GN=PSMA4 PE=1 SV=1 4.14 3668.6 - 5.25E+06 - - - 0.1111 - 2.205 0.474 - 289.1 1 2 0 0.0001 10 0 0 0 1.29E+08 1.04E+08 - - - 4.7491 0.9994 221125_WJC_METTL3_EV_vs_WT_F01.19505.19505.2 0.00929 18-Sep K.ELLGQGLLLR[166.11].S "sp|Q99613|EIF3C_HUMAN,sp|B5ME19|EIFCL_HUMAN" 2 1120.6844 0.93 7043 19505 2 1120.685671 561.3495 Eukaryotic translation initiation factor 3 subunit C OS=Homo sapiens OX=9606 GN=EIF3C PE=1 SV=1 6.1 3668.6 - 3.90E+06 - - - 1.1663 - 1.879 0.317 - 317 1 2 0 0.0013 10 0 0 0 6.26E+07 6.73E+07 - - - 3.1425 0.9058 221125_WJC_METTL3_EV_vs_WT_F01.19507.19507.2 0.0799 18-Jun K.GVLQTAAER[166.11]G.E sp|Q8TEQ6|GEMI5_HUMAN 1 1010.5384 4.66 7045 19507 2 1010.538579 506.2765 Gem-associated protein 5 OS=Homo sapiens OX=9606 GN=GEMIN5 PE=1 SV=3 6 3668.7 - 1.15E+06 - - - 0.1494 - 1.466 0.245 - 101.2 1 1 0 0.0002 10 0 0 0 3.48E+07 7.47E+06 - - - 1.9183 1 221125_WJC_METTL3_EV_vs_WT_F01.19508.19508.2 2.37E-10 14/26 L.GIETAGGVMTVLIK[136.11].R "sp|P11142|HSP7C_HUMAN,tr|E9PNE6|E9PNE6_HUMAN,tr|A8K7Q2|A8K7Q2_HUMAN,tr|E9PKE3|E9PKE3_HUMAN" 4 1395.7887 0.73 7046 19508 2 1395.786642 698.9016 Heat shock cognate 71 kDa protein OS=Homo sapiens OX=9606 GN=HSPA8 PE=1 SV=1 6 3668.8 - 917491 - - - -1.4651 - 2.837 0.607 - 444.3 1 1 0 -0.002 14 0 0 0 1.20E+07 1.66E+07 - - - 6.1404 0.9997 221125_WJC_METTL3_EV_vs_WT_F01.19509.19509.2 0.0308 24-Dec R.LENLGIPEEELLR[166.11].Q sp|Q01658|NC2B_HUMAN 1 1533.8278 1.25 7047 19509 2 1533.825262 767.9212 Protein Dr1 OS=Homo sapiens OX=9606 GN=DR1 PE=1 SV=1 4.09 3668.9 - 712111 - - - -1.6501 - 2.648 0.405 - 294.8 1 2 0 -0.0025 13 0 0 0 2.41E+07 1.92E+07 - - - 4.5308 0.9992 221125_WJC_METTL3_EV_vs_WT_F01.19510.19510.2 0.321 14-Aug K.DFLIPIGK[136.11].A "sp|P11177|ODPB_HUMAN,tr|F8WF02|F8WF02_HUMAN,tr|C9J634|C9J634_HUMAN" 3 909.5415 1.15 7048 19510 2 909.541436 455.778 "Pyruvate dehydrogenase E1 component subunit beta, mitochondrial OS=Homo sapiens OX=9606 GN=PDHB PE=1 SV=3" 5.84 3669.1 - 670913 - - - -0.0748 - 1.549 0.295 - 271.5 1 2 0 -0.0001 8 0 0 0 6.83E+07 5.94E+07 - - - 2.5397 1 221125_WJC_METTL3_EV_vs_WT_F01.19514.19514.2 1.07E-07 14/28 R.VMAGALEGDIFIGPK.A "sp|P61163|ACTZ_HUMAN,sp|P42025|ACTY_HUMAN,tr|R4GMT0|R4GMT0_HUMAN,tr|A0A1B0GVS3|A0A1B0GVS3_HUMAN" 4 1516.796 0.86 7052 19514 2 1516.795289 759.4053 Alpha-centractin OS=Homo sapiens OX=9606 GN=ACTR1A PE=1 SV=1 4.37 3669.6 - 165473 - - - -0.4364 - 2.713 0.608 - 543.1 1 2 0 -0.0007 15 0 0 0 2.00E+07 2.33E+07 - - - 5.9852 0.9998 221125_WJC_METTL3_EV_vs_WT_F01.19518.19518.2 0.00213 18-Sep K.SVLIGEFLEK[136.11].V "sp|O43148|MCES_HUMAN,tr|K7EP06|K7EP06_HUMAN" 2 1141.6474 0.95 7054 19518 2 1141.646824 571.831 mRNA cap guanine-N7 methyltransferase OS=Homo sapiens OX=9606 GN=RNMT PE=1 SV=1 4.53 3670 - 8.89E+06 - - - -0.5273 - 2.043 0.405 - 266 1 2 0 -0.0006 10 0 0 0 9.66E+07 1.01E+08 - - - 4.0263 0.9999 221125_WJC_METTL3_EV_vs_WT_F01.19519.19519.2 0.00049 20-Dec R.LFEAEAQDLFR.D sp|Q9H223|EHD4_HUMAN 1 1337.6616 1.71 7055 19519 2 1337.661204 669.8381 EH domain-containing protein 4 OS=Homo sapiens OX=9606 GN=EHD4 PE=1 SV=1 4.14 3670.1 - 1.63E+06 - - - -0.2706 - 2.443 0.473 - 569.8 1 2 0 -0.0004 11 0 0 0 6.57E+07 3.83E+07 - - - 4.9509 1 221125_WJC_METTL3_EV_vs_WT_F01.19520.19520.2 3.05E-09 13/26 R.IMGIPEEEQMGLLR.V sp|P35579|MYH9_HUMAN 1 1614.8109 0.88 7056 19520 2 1614.810088 808.4128 Myosin-9 OS=Homo sapiens OX=9606 GN=MYH9 PE=1 SV=4 4.25 3670.2 - 2.36E+06 - - - -0.5332 - 2.407 0.652 - 406.3 1 2 0 -0.0009 14 0 0 0 3.31E+07 3.77E+07 - - - 6.0607 0.9999 221125_WJC_METTL3_EV_vs_WT_F01.19521.19521.2 0.0174 13/20 R.LFEAEAQDLFR[166.11].D sp|Q9H223|EHD4_HUMAN 1 1347.6698 1.71 7057 19521 2 1347.668213 674.8422 EH domain-containing protein 4 OS=Homo sapiens OX=9606 GN=EHD4 PE=1 SV=1 4.14 3670.3 - 1.19E+06 - - - -1.2043 - 2.62 0.483 - 654 1 2 0 -0.0016 11 0 0 0 6.57E+07 3.83E+07 - - - 5.2135 0.9995 221125_WJC_METTL3_EV_vs_WT_F01.19523.19523.2 0.0398 20-Nov K.ALLLSSVLSEK[136.11].G "sp|O60315|ZEB2_HUMAN,tr|U3KQ51|U3KQ51_HUMAN,tr|E7EUW9|E7EUW9_HUMAN,tr|A0JP08|A0JP08_HUMAN,tr|A0A1B0GW50|A0A1B0GW50_HUMAN,tr|A0A1B0GV02|A0A1B0GV02_HUMAN,tr|A0A1B0GVV8|A0A1B0GVV8_HUMAN" 7 1166.7002 2.11 7059 19523 2 1166.698077 584.3574 Zinc finger E-box-binding homeobox 2 OS=Homo sapiens OX=9606 GN=ZEB2 PE=1 SV=1 6.05 3670.5 - 721952 - - - -1.8111 - 2.374 0.327 - 365.6 1 2 0 -0.0021 11 0 0 0 2.24E+07 1.06E+07 - - - 3.7944 0.9999 221125_WJC_METTL3_EV_vs_WT_F01.19525.19525.2 0.000602 13/22 R.LPADTC[160.03]LLEFAR[166.11].L "sp|Q8NF37|PCAT1_HUMAN,tr|A0A0G2JQ62|A0A0G2JQ62_HUMAN,tr|A0A0G2JRI7|A0A0G2JRI7_HUMAN" 3 1414.7154 0.67 7061 19525 2 1414.71364 708.365 Lysophosphatidylcholine acyltransferase 1 OS=Homo sapiens OX=9606 GN=LPCAT1 PE=1 SV=2 4.37 3670.8 - 432149 - - - -1.2483 - 2.589 0.491 - 738.3 1 2 0 -0.0018 12 0 0 0 5.81E+06 8.66E+06 - - - 5.1699 1 221125_WJC_METTL3_EV_vs_WT_F01.19529.19529.2 8.21E-06 14/24 A.TLSPTAVLILGPK.V "sp|Q8TDL5|BPIB1_HUMAN,tr|A2A2R0|A2A2R0_HUMAN" 2 1308.8017 999 7065 19529 2 1308.797014 655.4081 BPI fold-containing family B member 1 OS=Homo sapiens OX=9606 GN=BPIFB1 PE=1 SV=1 8.41 3671.3 - 308536 - - - -3.5712 - 2.893 0.628 - 629 1 1 0 -0.0047 13 0 0 0 1.10E+07 0.00E+00 - - - 6.4043 0.9947 221125_WJC_METTL3_EV_vs_WT_F01.19530.19530.2 0.335 12-Jun R.VLIWDIR[166.11].E "sp|Q96JK2|DCAF5_HUMAN,tr|G3V3S1|G3V3S1_HUMAN,tr|Q8TBB7|Q8TBB7_HUMAN" 3 923.5468 2.34 7066 19530 2 923.546488 462.7807 DDB1- and CUL4-associated factor 5 OS=Homo sapiens OX=9606 GN=DCAF5 PE=1 SV=2 5.81 3671.4 - 207688 - - - -0.3465 - 1.201 0.195 - 132.1 1 2 0 -0.0003 7 0 0 0 4.02E+06 1.72E+06 - - - 1.0615 0.9996 221125_WJC_METTL3_EV_vs_WT_F01.19537.19537.2 0.000195 20-Nov R.VLLQAFDVVER.S sp|Q15750|TAB1_HUMAN 1 1287.7187 1.59 7071 19537 2 1287.717449 644.8666 TGF-beta-activated kinase 1 and MAP3K7-binding protein 1 OS=Homo sapiens OX=9606 GN=TAB1 PE=1 SV=1 4.37 3672.2 - 811274 - - - -0.9614 - 2.329 0.269 - 582.2 1 2 0 -0.0012 11 0 0 0 2.18E+07 1.37E+07 - - - 3.3146 0.9975 221125_WJC_METTL3_EV_vs_WT_F01.19538.19538.2 0.573 14-Jul R.LSLELFGR.V "sp|O95071|UBR5_HUMAN,tr|E5RFK7|E5RFK7_HUMAN,tr|E7EMW7|E7EMW7_HUMAN" 3 933.5284 0.56 7072 19538 2 933.529436 467.7715 E3 ubiquitin-protein ligase UBR5 OS=Homo sapiens OX=9606 GN=UBR5 PE=1 SV=2 6 3672.4 - 422589 - - - 1.1451 - 1.673 0.177 - 135.9 1 2 0 0.0011 8 0 0 0 5.81E+06 1.04E+07 - - - 1.9001 0.9995 221125_WJC_METTL3_EV_vs_WT_F01.19554.19554.2 7.93E-06 20-Nov R.VLLQAFDVVER[166.11].S sp|Q15750|TAB1_HUMAN 1 1297.727 1.59 7084 19554 2 1297.724812 649.8708 TGF-beta-activated kinase 1 and MAP3K7-binding protein 1 OS=Homo sapiens OX=9606 GN=TAB1 PE=1 SV=1 4.37 3674.4 - 1.08E+06 - - - -1.6529 - 2.344 0.294 - 582.1 1 2 0 -0.0021 11 0 0 0 2.18E+07 1.37E+07 - - - 3.5163 0.9997 221125_WJC_METTL3_EV_vs_WT_F01.19555.19555.2 0.0097 18-Sep R.GPILLPYQFR.M "sp|Q9NY93|DDX56_HUMAN,tr|H7BZN7|H7BZN7_HUMAN,tr|H7C3E9|H7C3E9_HUMAN" 3 1202.6812 1.23 7085 19555 2 1202.681449 602.3479 Probable ATP-dependent RNA helicase DDX56 OS=Homo sapiens OX=9606 GN=DDX56 PE=1 SV=1 8.75 3674.5 - 1.17E+06 - - - 0.2245 - 1.832 0.37 - 338.3 1 2 0 0.0003 10 0 0 0 1.56E+07 1.27E+07 - - - 3.4636 0.9921 221125_WJC_METTL3_EV_vs_WT_F01.19557.19557.2 0.0937 18-Jul K.NIFSVPEIVR.E "sp|O60645|EXOC3_HUMAN,tr|D6RB59|D6RB59_HUMAN" 2 1172.6554 0.95 7087 19557 2 1172.656806 587.335 Exocyst complex component 3 OS=Homo sapiens OX=9606 GN=EXOC3 PE=1 SV=3 6 3674.7 - 578498 - - - 1.234 - 1.469 0.146 - 125.3 2 2 0 0.0014 10 0 0 0 9.13E+06 9.60E+06 - - - 1.0579 0.9976 221125_WJC_METTL3_EV_vs_WT_F01.19562.19562.2 0.365 16-Sep K.TLFPLIEAK[136.11].K sp|P13010|XRCC5_HUMAN 1 1038.6205 1.07 7091 19562 2 1038.620791 520.3175 X-ray repair cross-complementing protein 5 OS=Homo sapiens OX=9606 GN=XRCC5 PE=1 SV=3 5.66 3675.2 - 3.41E+06 - - - 0.2965 - 1.49 0.199 - 231.8 1 2 0 0.0003 9 0 0 0 2.05E+08 1.92E+08 - - - 1.6644 1 221125_WJC_METTL3_EV_vs_WT_F01.19563.19563.2 4.88E-06 13/22 R.IYGLGSLALYEK[136.11].A sp|P36542|ATPG_HUMAN 1 1333.7373 1.22 7092 19563 2 1333.736329 667.8759 "ATP synthase subunit gamma, mitochondrial OS=Homo sapiens OX=9606 GN=ATP5F1C PE=1 SV=1" 6 3675.3 - 5.93E+06 - - - -0.731 - 2.636 0.568 - 473.1 1 2 0 -0.001 12 0 0 0 1.95E+08 1.60E+08 - - - 5.7862 0.9987 221125_WJC_METTL3_EV_vs_WT_F01.19569.19569.2 0.00834 24-Aug K.FEQAQMLDPYLIK[136.11].G sp|Q9UJX3|APC7_HUMAN 1 1602.8207 0.87 7098 19569 2 1602.820915 802.4176 Anaphase-promoting complex subunit 7 OS=Homo sapiens OX=9606 GN=ANAPC7 PE=1 SV=4 4.37 3675.9 - 253166 - - - 0.1242 - 1.345 0.314 - 122.9 1 2 0 0.0002 13 0 0 0 1.50E+06 1.72E+06 - - - 2.1208 0.9795 221125_WJC_METTL3_EV_vs_WT_F01.19573.19573.2 0.0123 12-Sep L.PDWFLNR[166.11].Q "sp|P62269|RS18_HUMAN,tr|J3JS69|J3JS69_HUMAN" 2 956.4744 3.51 7100 19573 2 956.472992 479.2445 40S ribosomal protein S18 OS=Homo sapiens OX=9606 GN=RPS18 PE=1 SV=3 6.27 3676.5 - 987728 - - - -1.4418 - 1.847 0.393 - 317.7 1 1 0 -0.0014 7 0 0 0 4.72E+07 1.34E+07 - - - 3.8874 0.9874 221125_WJC_METTL3_EV_vs_WT_F01.19574.19574.2 0.000645 18-Sep A.GFMDVISIDK.T sp|P62701|RS4X_HUMAN 1 1123.5583 0.93 7101 19574 2 1123.55694 562.7864 "40S ribosomal protein S4, X isoform OS=Homo sapiens OX=9606 GN=RPS4X PE=1 SV=2" 4.21 3676.6 - 837694 - - - -1.2523 - 1.886 0.489 - 190.5 1 1 0 -0.0014 10 0 0 0 1.11E+07 1.20E+07 - - - 4.4233 0.9874 221125_WJC_METTL3_EV_vs_WT_F01.19575.19575.2 1.22E-05 18-Sep A.GFMDVISIDK[136.11].T sp|P62701|RS4X_HUMAN 1 1131.5725 0.92 7102 19575 2 1131.572801 566.7935 "40S ribosomal protein S4, X isoform OS=Homo sapiens OX=9606 GN=RPS4X PE=1 SV=2" 4.21 3676.7 - 851049 - - - 0.2245 - 1.853 0.443 - 212.6 1 1 0 0.0003 10 0 0 0 1.11E+07 1.21E+07 - - - 4.0346 0.9998 221125_WJC_METTL3_EV_vs_WT_F01.19583.19583.2 0.000531 14-Sep K.IPDWFLNR[166.11].Q "sp|P62269|RS18_HUMAN,tr|J3JS69|J3JS69_HUMAN" 2 1069.5584 0.94 7109 19583 2 1069.557838 535.7865 40S ribosomal protein S18 OS=Homo sapiens OX=9606 GN=RPS18 PE=1 SV=3 5.84 3677.7 - 1.01E+08 - - - -0.5582 - 1.991 0.45 - 425.3 1 2 0 -0.0006 8 0 0 0 1.38E+09 1.47E+09 - - - 4.4414 0.9996 221125_WJC_METTL3_EV_vs_WT_F01.19587.19587.2 0.00158 16-Sep R.ILDTLGLLR[166.11].Q "sp|Q9BWU0|NADAP_HUMAN,tr|A0A087X0M4|A0A087X0M4_HUMAN,tr|A0A087WWF4|A0A087WWF4_HUMAN" 3 1022.6364 0.81 7112 19587 2 1022.636704 512.3255 Kanadaptin OS=Homo sapiens OX=9606 GN=SLC4A1AP PE=1 SV=1 5.84 3678.1 - 848984 - - - 0.3452 - 1.928 0.331 - 195.4 1 2 0 0.0004 9 0 0 0 5.18E+06 6.41E+06 - - - 3.3849 0.9998 221125_WJC_METTL3_EV_vs_WT_F01.19589.19589.2 0.000289 24-Nov R.LLLFSSATDAAIR.V "sp|Q12788|TBL3_HUMAN,tr|J3KNP2|J3KNP2_HUMAN,tr|A0A087WYP7|A0A087WYP7_HUMAN" 3 1376.7664 0.54 7114 19589 2 1376.766132 689.3905 Transducin beta-like protein 3 OS=Homo sapiens OX=9606 GN=TBL3 PE=1 SV=2 5.84 3678.3 - 614967 - - - -0.17 - 2.046 0.476 - 362.4 1 2 0 -0.0002 13 0 0 0 5.27E+06 9.68E+06 - - - 4.394 0.9952 221125_WJC_METTL3_EV_vs_WT_F01.19592.19592.2 0.000112 20-Oct K.SFYGSTLFLC[160.03]R[166.11].R "sp|P49327|FAS_HUMAN,tr|A0A0U1RQF0|A0A0U1RQF0_HUMAN" 2 1359.6521 0.6 7117 19592 2 1359.659946 680.8333 Fatty acid synthase OS=Homo sapiens OX=9606 GN=FASN PE=1 SV=3 7.94 3678.7 - 578475 - - - 5.7868 - 2.013 0.497 - 306.6 1 2 0 0.0079 11 0 0 0 2.68E+06 4.49E+06 - - - 4.602 0.9977 221125_WJC_METTL3_EV_vs_WT_F01.19594.19594.2 0.0243 14-Jul K.LDGFPLLR.R "sp|P09661|RU2A_HUMAN,tr|H0YKK0|H0YKK0_HUMAN" 2 929.5335 1.26 7119 19594 2 929.535579 465.774 U2 small nuclear ribonucleoprotein A' OS=Homo sapiens OX=9606 GN=SNRPA1 PE=1 SV=2 5.84 3678.9 - 418028 - - - 2.2882 - 1.657 0.269 - 116.6 1 2 0 0.0021 8 0 0 0 5.87E+06 4.66E+06 - - - 2.5502 0.8547 221125_WJC_METTL3_EV_vs_WT_F01.19602.19602.2 1.52 18-Jul R.NVQALEIELQ.S "sp|P13645|K1C10_HUMAN,tr|A0A1B0GVI3|A0A1B0GVI3_HUMAN" 2 1155.6136 - 7125 19602 2 1155.613665 578.8141 "Keratin, type I cytoskeletal 10 OS=Homo sapiens OX=9606 GN=KRT10 PE=1 SV=6" 3.79 3680 - 2.26E+06 - - - 0.0969 - 1.413 0.206 - 163.8 1 1 0 0.0001 10 0 0 0 - - - - - 1.5275 0.9933 221125_WJC_METTL3_EV_vs_WT_F01.19603.19603.2 0.237 12-Jul K.LLDDLFR[166.11].K "sp|Q9UKV3|ACINU_HUMAN,tr|G3V3B0|G3V3B0_HUMAN,tr|S4R3H4|S4R3H4_HUMAN,tr|E7EQT4|E7EQT4_HUMAN" 4 900.4944 1.32 7126 19603 2 900.494271 451.2545 Apoptotic chromatin condensation inducer in the nucleus OS=Homo sapiens OX=9606 GN=ACIN1 PE=1 SV=2 4.21 3680.1 - 1.64E+06 - - - -0.1855 - 1.3 0.138 - 143.3 1 2 0 -0.0002 7 0 0 0 7.85E+07 5.95E+07 - - - 0.8915 0.9963 221125_WJC_METTL3_EV_vs_WT_F01.19604.19604.2 0.553 12-Jul K.LLDDLFR.K "sp|Q9UKV3|ACINU_HUMAN,tr|G3V3B0|G3V3B0_HUMAN,tr|S4R3H4|S4R3H4_HUMAN,tr|E7EQT4|E7EQT4_HUMAN" 4 890.4862 1.32 7127 19604 2 890.485753 446.2504 Apoptotic chromatin condensation inducer in the nucleus OS=Homo sapiens OX=9606 GN=ACIN1 PE=1 SV=2 4.21 3680.1 - 1.21E+06 - - - -0.466 - 1.331 0.187 - 147.9 1 2 0 -0.0004 7 0 0 0 7.85E+07 5.95E+07 - - - 1.328 0.932 221125_WJC_METTL3_EV_vs_WT_F01.19605.19605.2 0.0291 16-Sep K.QLLLSFKPV.M "sp|P78344|IF4G2_HUMAN,tr|H0Y3P2|H0Y3P2_HUMAN,tr|H0YE22|H0YE22_HUMAN,tr|D3DQV9|D3DQV9_HUMAN" 4 1043.6379 4.46 7128 19605 2 1043.638452 522.8262 Eukaryotic translation initiation factor 4 gamma 2 OS=Homo sapiens OX=9606 GN=EIF4G2 PE=1 SV=1 8.75 3680.3 - 1.12E+06 - - - 0.5117 - 1.589 0.257 - 214.3 1 1 0 0.0005 9 0 0 0 1.50E+07 3.36E+06 - - - 2.2788 1 221125_WJC_METTL3_EV_vs_WT_F01.19606.19606.2 2.15E-05 16/24 K.IYVDDGLISLQVK.Q "sp|P14618|KPYM_HUMAN,tr|H3BQ34|H3BQ34_HUMAN,tr|B4DNK4|B4DNK4_HUMAN,tr|A0A804F6T5|A0A804F6T5_HUMAN,tr|H3BTN5|H3BTN5_HUMAN,tr|A0A804F729|A0A804F729_HUMAN" 6 1461.8079 0.93 7129 19606 2 1461.808915 731.9112 Pyruvate kinase PKM OS=Homo sapiens OX=9606 GN=PKM PE=1 SV=4 4.21 3680.4 - 1.09E+06 - - - 0.6971 - 2.742 0.578 - 708.7 1 2 0 0.001 13 0 0 0 7.18E+06 7.71E+06 - - - 5.8986 0.9999 221125_WJC_METTL3_EV_vs_WT_F01.19608.19608.2 7.69E-07 13/24 K.IYVDDGLISLQVK[136.11].Q "sp|P14618|KPYM_HUMAN,tr|H3BQ34|H3BQ34_HUMAN,tr|B4DNK4|B4DNK4_HUMAN,tr|A0A804F6T5|A0A804F6T5_HUMAN,tr|H3BTN5|H3BTN5_HUMAN,tr|A0A804F729|A0A804F729_HUMAN" 6 1469.8221 0.93 7131 19608 2 1469.82227 735.9183 Pyruvate kinase PKM OS=Homo sapiens OX=9606 GN=PKM PE=1 SV=4 4.21 3680.6 - 1.05E+06 - - - 0.1184 - 2.271 0.542 - 419.5 1 2 0 0.0002 13 0 0 0 7.18E+06 7.71E+06 - - - 5.1493 1 221125_WJC_METTL3_EV_vs_WT_F01.19609.19609.2 7.13E-08 14/26 L.GLETAGGVMTALIK[136.11].R "sp|P0DMV8|HS71A_HUMAN,sp|P34931|HS71L_HUMAN,sp|P0DMV9|HS71B_HUMAN,tr|Q53FA3|Q53FA3_HUMAN,tr|V9GZ37|V9GZ37_HUMAN,tr|A0A0G2JIW1|A0A0G2JIW1_HUMAN" 6 1367.7574 0.06 7132 19609 2 1367.758142 684.886 Heat shock 70 kDa protein 1A OS=Homo sapiens OX=9606 GN=HSPA1A PE=1 SV=1 6 3680.7 - 983729 - - - 0.552 - 2.946 0.578 - 529.7 1 1 0 0.0008 14 0 0 0 3.37E+05 5.40E+06 - - - 6.0212 0.9987 221125_WJC_METTL3_EV_vs_WT_F01.19610.19610.2 0.02 18-Jul K.IINFAPSLLR.L "sp|O15397|IPO8_HUMAN,tr|F5H2I3|F5H2I3_HUMAN" 2 1142.6812 1.52 7133 19610 2 1142.683043 572.3479 Importin-8 OS=Homo sapiens OX=9606 GN=IPO8 PE=1 SV=2 9.75 3680.8 - 965174 - - - 1.6313 - 1.827 0.265 - 118.8 1 2 0 0.0019 10 0 0 0 2.13E+07 1.40E+07 - - - 2.68 0.9646 221125_WJC_METTL3_EV_vs_WT_F01.19613.19613.2 0.0273 20-Sep K.IFTMAEVYGIR[166.11].T sp|Q96P70|IPO9_HUMAN 1 1308.6776 0.39 7136 19613 2 1309.682363 655.3461 Importin-9 OS=Homo sapiens OX=9606 GN=IPO9 PE=1 SV=3 6 3681.2 - 314270 - - - 767.7972 - 2.048 0.286 - 234 1 2 0 1.0048 11 0 0 0 1.45E+06 3.68E+06 - - - 2.7772 0.9991 221125_WJC_METTL3_EV_vs_WT_F01.19616.19616.2 0.0185 16-Jul K.FFPLIEVNK[136.11].V "sp|P27694|RFA1_HUMAN,tr|I3L4R8|I3L4R8_HUMAN" 2 1113.6314 0.79 7138 19616 2 1113.631723 557.823 Replication protein A 70 kDa DNA-binding subunit OS=Homo sapiens OX=9606 GN=RPA1 PE=1 SV=2 6 3681.6 - 5.72E+06 - - - 0.3062 - 1.231 0.39 - 112.1 1 2 0 0.0003 9 0 0 0 2.01E+08 2.53E+08 - - - 2.5227 0.9997 221125_WJC_METTL3_EV_vs_WT_F01.19619.19619.2 0.000354 18-Aug K.GIYLWDVEGR.K sp|P04181|OAT_HUMAN 1 1206.6033 1.06 7141 19619 2 1206.604746 604.3089 "Ornithine aminotransferase, mitochondrial OS=Homo sapiens OX=9606 GN=OAT PE=1 SV=1" 4.37 3681.9 - 1.54E+06 - - - 1.1793 - 1.753 0.474 - 196.2 1 2 0 0.0014 10 0 0 0 7.58E+06 7.12E+06 - - - 4.1084 0.9997 221125_WJC_METTL3_EV_vs_WT_F01.19620.19620.2 0.000509 20-Nov -.MLLFVEQVASK.G "sp|Q71RC2|LARP4_HUMAN,tr|F8W1Z5|F8W1Z5_HUMAN" 2 1263.6897 0.28 7142 19620 2 1263.689595 632.8521 La-related protein 4 OS=Homo sapiens OX=9606 GN=LARP4 PE=1 SV=3 5.75 3682 - 1.37E+06 - - - -0.0791 - 2.199 0.331 - 373.9 1 2 0 -0.0001 11 0 0 0 9.00E+06 3.25E+07 - - - 3.6175 0.9998 221125_WJC_METTL3_EV_vs_WT_F01.19621.19621.2 0.017 13/22 K.LANILFTQELAR.R "sp|Q8TC12|RDH11_HUMAN,tr|G3V234|G3V234_HUMAN,tr|H0YIZ8|H0YIZ8_HUMAN,tr|G3V2G6|G3V2G6_HUMAN,tr|H0YJ46|H0YJ46_HUMAN" 5 1387.7823 1.06 7143 19621 2 1387.781735 694.8985 Retinol dehydrogenase 11 OS=Homo sapiens OX=9606 GN=RDH11 PE=1 SV=2 6 3682.1 - 1.25E+06 - - - -0.4432 - 2.814 0.289 - 718.5 1 2 0 -0.0006 12 0 0 0 1.26E+07 1.19E+07 - - - 3.8976 0.9998 221125_WJC_METTL3_EV_vs_WT_F01.19622.19622.2 2.28E-06 14/22 K.ALEDAFLAIDAK.L sp|O15355|PPM1G_HUMAN 1 1275.6711 0.73 7144 19622 2 1275.669216 638.8428 Protein phosphatase 1G OS=Homo sapiens OX=9606 GN=PPM1G PE=1 SV=1 4.03 3682.1 - 989352 - - - -1.4518 - 2.641 0.485 - 573 1 2 0 -0.0019 12 0 0 0 1.00E+07 1.38E+07 - - - 5.1779 0.9755 221125_WJC_METTL3_EV_vs_WT_F01.19631.19631.3 0.0736 Aug-96 R.AETSDVANAVLDGADC[160.03]IMLSGETAK.G sp|P30613|KPYR_HUMAN 1 2537.1625 999 7153 19631 3 2537.166826 846.7281 Pyruvate kinase PKLR OS=Homo sapiens OX=9606 GN=PKLR PE=1 SV=2 3.77 3683.3 - 335719 - - - 1.6917 - 1.423 0.197 - 62 1 2 0 0.0043 25 0 0 0 1.43E+06 0.00E+00 - - - 1.5468 0.9997 221125_WJC_METTL3_EV_vs_WT_F01.19637.19637.2 0.00214 14-Aug K.IPDWFLNR.Q "sp|P62269|RS18_HUMAN,tr|J3JS69|J3JS69_HUMAN" 2 1059.5502 0.94 7158 19637 2 1059.551371 530.7824 40S ribosomal protein S18 OS=Homo sapiens OX=9606 GN=RPS18 PE=1 SV=3 5.84 3684 - 3.64E+07 - - - 1.1382 - 1.746 0.443 - 304.1 1 2 0 0.0012 8 0 0 0 1.38E+09 1.47E+09 - - - 3.9935 0.9978 221125_WJC_METTL3_EV_vs_WT_F01.19639.19639.2 1.61 18-Aug K.IINFAPSLLR[166.11].L "sp|O15397|IPO8_HUMAN,tr|F5H2I3|F5H2I3_HUMAN" 2 1152.6894 1.52 7160 19639 2 1152.691348 577.352 Importin-8 OS=Homo sapiens OX=9606 GN=IPO8 PE=1 SV=2 9.75 3684.1 - 2.94E+06 - - - 1.6475 - 1.779 0.212 - 180.7 1 2 0 0.0019 10 0 0 0 2.13E+07 1.40E+07 - - - 2.2142 0.9999 221125_WJC_METTL3_EV_vs_WT_F01.19640.19640.2 2.25E-08 14/22 K.ALEDAFLAIDAK[136.11].L sp|O15355|PPM1G_HUMAN 1 1283.6853 0.8 7161 19640 2 1283.685377 642.8499 Protein phosphatase 1G OS=Homo sapiens OX=9606 GN=PPM1G PE=1 SV=1 4.03 3684.2 - 2.46E+06 - - - 0.0849 - 2.631 0.559 - 546.2 1 2 0 0.0001 12 0 0 0 9.26E+06 1.16E+07 - - - 5.715 0.9984 221125_WJC_METTL3_EV_vs_WT_F01.19641.19641.2 0.0222 18-Oct K.GIGFLTSGWR.F sp|Q8IXM3|RM41_HUMAN 1 1092.5716 1.38 7162 19641 2 1092.575205 547.2931 "39S ribosomal protein L41, mitochondrial OS=Homo sapiens OX=9606 GN=MRPL41 PE=1 SV=1" 9.75 3684.3 - 1.26E+06 - - - 3.273 - 1.965 0.365 - 311.5 1 2 0 0.0036 10 0 0 0 5.45E+07 3.95E+07 - - - 3.6213 0.9997 221125_WJC_METTL3_EV_vs_WT_F01.19642.19642.2 0.000314 20-Aug K.IESLPPLLIGK[136.11].F "sp|Q8N9N7|LRC57_HUMAN,tr|A0A3B3ISV5|A0A3B3ISV5_HUMAN,tr|H3BSW0|H3BSW0_HUMAN" 3 1186.7417 2.17 7163 19642 2 1186.741894 594.3781 Leucine-rich repeat-containing protein 57 OS=Homo sapiens OX=9606 GN=LRRC57 PE=1 SV=1 6 3684.4 - 576726 - - - 0.1963 - 1.671 0.423 - 144.4 1 2 0 0.0002 11 0 0 0 4.12E+06 1.90E+06 - - - 3.5541 0.9938 221125_WJC_METTL3_EV_vs_WT_F01.19646.19646.2 0.374 14-Sep R.SLLSILQR[166.11].S "sp|Q7Z6Z7|HUWE1_HUMAN,tr|H0Y659|H0Y659_HUMAN" 2 938.5788 0.88 7167 19646 2 938.58033 470.2967 E3 ubiquitin-protein ligase HUWE1 OS=Homo sapiens OX=9606 GN=HUWE1 PE=1 SV=3 9.47 3684.9 - 433296 - - - 1.5918 - 1.747 0.088 - 251.9 1 2 0 0.0015 8 0 0 0 3.77E+06 4.30E+06 - - - 1.3731 0.9859 221125_WJC_METTL3_EV_vs_WT_F01.19649.19649.2 0.375 12-Jul R.WLSQYID.- "sp|Q9NR31|SAR1A_HUMAN,tr|H0Y5E8|H0Y5E8_HUMAN" 2 923.4389 - 7170 19649 2 923.438999 462.7267 GTP-binding protein SAR1a OS=Homo sapiens OX=9606 GN=SAR1A PE=1 SV=1 4.3 3685.3 - 302446 - - - 0.1256 - 0.984 0.19 - 110.4 1 2 0 0.0001 7 0 0 0 - - - - - 0.3932 0.9993 221125_WJC_METTL3_EV_vs_WT_F01.19652.19652.2 0.424 28-Aug R.LLGVPIIVQASQAEK[136.11].N "sp|Q86U06|RBM23_HUMAN,tr|G3XAP0|G3XAP0_HUMAN,tr|G3V546|G3V546_HUMAN" 3 1572.933 1.38 7173 19652 2 1572.932388 787.4738 Probable RNA-binding protein 23 OS=Homo sapiens OX=9606 GN=RBM23 PE=1 SV=1 6 3685.7 - 222968 - - - -0.4171 - 1.636 0.332 - 64.7 1 2 0 -0.0007 15 0 0 0 4.02E+06 2.91E+06 - - - 2.7032 0.9994 221125_WJC_METTL3_EV_vs_WT_F01.19654.19654.2 7.63E-06 28-Dec R.LLGVPIIVQASQAEK.N "sp|Q86U06|RBM23_HUMAN,tr|G3XAP0|G3XAP0_HUMAN,tr|G3V546|G3V546_HUMAN" 3 1564.9188 1.38 7175 19654 2 1564.924112 783.4667 Probable RNA-binding protein 23 OS=Homo sapiens OX=9606 GN=RBM23 PE=1 SV=1 6 3685.9 - 210379 - - - 3.3663 - 2.281 0.568 - 345.1 1 2 0 0.0053 15 0 0 0 4.02E+06 2.91E+06 - - - 5.2619 1 221125_WJC_METTL3_EV_vs_WT_F01.19659.19659.2 5.14E-07 14/20 K.TAVETAVLLLR[166.11].L "sp|P49368|TCPG_HUMAN,tr|B4DUR8|B4DUR8_HUMAN" 2 1194.7211 0.23 7179 19659 2 1194.72233 598.3678 T-complex protein 1 subunit gamma OS=Homo sapiens OX=9606 GN=CCT3 PE=1 SV=4 5.66 3686.4 - 2.32E+07 - - - 0.9935 - 2.893 0.56 - 834.6 1 2 0 0.0012 11 0 0 0 2.29E+08 9.76E+08 - - - 6.0505 1 221125_WJC_METTL3_EV_vs_WT_F01.19660.19660.2 4.66E-05 20-Dec K.TAVETAVLLLR.L "sp|P49368|TCPG_HUMAN,tr|B4DUR8|B4DUR8_HUMAN" 2 1184.7129 0.23 7180 19660 2 1184.715036 593.3637 T-complex protein 1 subunit gamma OS=Homo sapiens OX=9606 GN=CCT3 PE=1 SV=4 5.66 3686.5 - 3.99E+06 - - - 1.8258 - 2.674 0.568 - 603.5 1 2 0 0.0022 11 0 0 0 2.29E+08 9.76E+08 - - - 5.8964 1 221125_WJC_METTL3_EV_vs_WT_F01.19661.19661.3 0.000493 15/40 K.TAVETAVLLLR[166.11].L "sp|P49368|TCPG_HUMAN,tr|B4DUR8|B4DUR8_HUMAN" 2 1194.7211 0.23 7181 19661 3 1194.722078 399.2477 T-complex protein 1 subunit gamma OS=Homo sapiens OX=9606 GN=CCT3 PE=1 SV=4 5.66 3686.6 - 1.54E+06 - - - 0.7826 - 2.489 0.448 - 410.1 1 2 0 0.0009 11 0 0 0 1.21E+07 5.18E+07 - - - 6.125 1 221125_WJC_METTL3_EV_vs_WT_F01.19663.19663.2 1.09E-07 19/30 K.K[136.11]VSQEILELLNTTTAK[136.11].E "sp|Q86U44|MTA70_HUMAN,tr|H0YFV6|H0YFV6_HUMAN" 2 1803.0324 0.001 7183 19663 2 1803.031988 902.5235 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 6.14 3686.8 - 1.13E+06 - - - -0.2451 - 4.072 0.67 - 1058.3 1 2 0 -0.0004 16 0 0 0 0.00E+00 1.24E+07 - - - 7.4416 0.9868 221125_WJC_METTL3_EV_vs_WT_F01.19668.19668.2 2.24 18-Sep R.NVEELVIVLK[136.11].K "sp|P53618|COPB_HUMAN,tr|E9PP73|E9PP73_HUMAN" 2 1162.7053 2.19 7188 19668 2 1162.706324 582.3599 Coatomer subunit beta OS=Homo sapiens OX=9606 GN=COPB1 PE=1 SV=3 4.53 3687.4 - 395180 - - - 0.9022 - 1.509 0.054 - 104.5 1 2 0 0.001 10 0 0 0 3.64E+06 1.67E+06 - - - 0.588 0.9955 221125_WJC_METTL3_EV_vs_WT_F01.19669.19669.2 1.19 14-Sep R.SLLSILQR.S "sp|Q7Z6Z7|HUWE1_HUMAN,tr|H0Y659|H0Y659_HUMAN" 2 928.5706 0.66 7189 19669 2 928.571184 465.2926 E3 ubiquitin-protein ligase HUWE1 OS=Homo sapiens OX=9606 GN=HUWE1 PE=1 SV=3 9.47 3687.5 - 389850 - - - 0.6655 - 1.523 0.132 - 177.8 1 2 0 0.0006 8 0 0 0 2.78E+06 4.22E+06 - - - 1.2845 0.9999 221125_WJC_METTL3_EV_vs_WT_F01.19670.19670.2 1.70E-07 30-Dec K.LVLVSPTSEQYDSLLR[166.11].Q sp|O00178|GTPB1_HUMAN 1 1828.981 0.5 7190 19670 2 1828.982045 915.4978 GTP-binding protein 1 OS=Homo sapiens OX=9606 GN=GTPBP1 PE=1 SV=3 4.37 3687.6 - 357660 - - - 0.5714 - 2.45 0.573 - 320.8 1 2 0 0.001 16 0 0 0 7.88E+05 1.58E+06 - - - 5.4759 0.9999 221125_WJC_METTL3_EV_vs_WT_F01.19671.19671.2 4.62E-07 24-Nov K.C[160.03]EFQDAYVLLSEK[136.11].K "sp|P10809|CH60_HUMAN,tr|A0A7I2V2X6|A0A7I2V2X6_HUMAN,tr|A0A7I2YQK6|A0A7I2YQK6_HUMAN,tr|A0A7I2V599|A0A7I2V599_HUMAN,tr|A0A7I2YQ71|A0A7I2YQ71_HUMAN,tr|A0A7I2V5M1|A0A7I2V5M1_HUMAN,tr|A0A7I2V5K3|A0A7I2V5K3_HUMAN,tr|A0A7I2V369|A0A7I2V369_HUMAN" 8 1608.7585 0.65 7191 19671 2 1608.759261 805.3865 "60 kDa heat shock protein, mitochondrial OS=Homo sapiens OX=9606 GN=HSPD1 PE=1 SV=2" 4.14 3687.8 - 302421 - - - 0.4668 - 2.332 0.561 - 318.8 1 2 0 0.0008 13 0 0 0 1.24E+06 1.91E+06 - - - 5.3575 0.9317 221125_WJC_METTL3_EV_vs_WT_F01.19674.19674.2 0.104 16-Sep C.LLSLLPVPR.D "sp|Q9ULV3|CIZ1_HUMAN,tr|Q5SYW2|Q5SYW2_HUMAN,tr|F5H2X7|F5H2X7_HUMAN,tr|H0Y5D5|H0Y5D5_HUMAN,tr|A0A0U1RQR2|A0A0U1RQR2_HUMAN,tr|A0A494C0L7|A0A494C0L7_HUMAN,tr|Q9BTG3|Q9BTG3_HUMAN" 7 1006.6539 3.86 7193 19674 2 1006.655592 504.3342 Cip1-interacting zinc finger protein OS=Homo sapiens OX=9606 GN=CIZ1 PE=1 SV=2 9.75 3688.1 - 1.27E+06 - - - 1.6788 - 1.823 0.271 - 282.2 1 1 0 0.0017 9 0 0 0 9.76E+06 2.53E+06 - - - 2.7793 0.9993 221125_WJC_METTL3_EV_vs_WT_F01.19677.19677.2 0.000206 13/22 R.AVLTFALDSVER[166.11].K "sp|Q9NQT4|EXOS5_HUMAN,tr|M0R050|M0R050_HUMAN" 2 1329.7168 1.22 7196 19677 2 1329.720417 665.8657 Exosome complex component RRP46 OS=Homo sapiens OX=9606 GN=EXOSC5 PE=1 SV=1 4.37 3688.4 - 930400 - - - 2.7307 - 2.34 0.402 - 541.4 1 2 0 0.0036 12 0 0 0 1.56E+07 1.28E+07 - - - 4.2459 0.9986 221125_WJC_METTL3_EV_vs_WT_F01.19678.19678.2 0.512 12-Aug R.WIVNLIR.N "sp|P60228|EIF3E_HUMAN,tr|A0A7I2V3I2|A0A7I2V3I2_HUMAN,tr|H0YBP5|H0YBP5_HUMAN,tr|A0A7I2V5Z6|A0A7I2V5Z6_HUMAN,tr|A0A7I2V2H9|A0A7I2V2H9_HUMAN,tr|B3KW56|B3KW56_HUMAN,tr|H0YAW4|H0YAW4_HUMAN,tr|A0A7I2V4B4|A0A7I2V4B4_HUMAN,tr|E5RGA2|E5RGA2_HUMAN,tr|A0A7I2V3I0|A0A7I2V3I0_HUMAN,tr|A0A7I2V3S3|A0A7I2V3S3_HUMAN,tr|A0A7I2V4G3|A0A7I2V4G3_HUMAN,tr|E5RHS5|E5RHS5_HUMAN,tr|A0A7I2V2W0|A0A7I2V2W0_HUMAN,tr|A0A7I2V5P9|A0A7I2V5P9_HUMAN" 15 912.5545 0.99 7197 19678 2 912.554017 457.2845 Eukaryotic translation initiation factor 3 subunit E OS=Homo sapiens OX=9606 GN=EIF3E PE=1 SV=1 9.75 3688.5 - 913144 - - - -0.5534 - 1.462 0.25 - 250.3 1 2 0 -0.0005 7 0 0 0 2.45E+07 2.48E+07 - - - 2.0908 0.9999 221125_WJC_METTL3_EV_vs_WT_F01.19679.19679.3 0.00458 14/40 K.TAVETAVLLLR.L "sp|P49368|TCPG_HUMAN,tr|B4DUR8|B4DUR8_HUMAN" 2 1184.7129 0.23 7198 19679 3 1184.712476 395.9116 T-complex protein 1 subunit gamma OS=Homo sapiens OX=9606 GN=CCT3 PE=1 SV=4 5.66 3688.6 - 698885 - - - -0.3351 - 2.468 0.375 - 241.9 1 2 0 -0.0004 11 0 0 0 1.21E+07 5.18E+07 - - - 5.2872 0.9999 221125_WJC_METTL3_EV_vs_WT_F01.19683.19683.2 0.000133 30-Oct K.LVLVSPTSEQYDSLLR.Q sp|O00178|GTPB1_HUMAN 1 1818.9727 -1 7202 19683 2 1818.973041 910.4936 GTP-binding protein 1 OS=Homo sapiens OX=9606 GN=GTPBP1 PE=1 SV=3 4.37 3689.1 - 223069 - - - 0.171 - 2.204 0.519 - 216.5 1 2 0 0.0003 16 0 0 0 0.00E+00 0.00E+00 - - - 4.8172 0.9992 221125_WJC_METTL3_EV_vs_WT_F01.19684.19684.2 9.93E-07 20-Nov K.TYSYLTPDLWK.E "sp|P15880|RS2_HUMAN,tr|E9PQD7|E9PQD7_HUMAN,tr|H0YEN5|H0YEN5_HUMAN" 3 1385.6867 0.96 7203 19684 2 1385.690396 693.8506 40S ribosomal protein S2 OS=Homo sapiens OX=9606 GN=RPS2 PE=1 SV=2 5.5 3689.2 - 210265 - - - 2.6543 - 1.853 0.428 - 157.9 1 2 0 0.0037 11 0 0 0 6.13E+07 6.41E+07 - - - 3.8697 0.9959 221125_WJC_METTL3_EV_vs_WT_F01.19688.19688.2 0.0309 12-Aug K.LFFLQVK[136.11].E "sp|P15311|EZRI_HUMAN,sp|P26038|MOES_HUMAN,sp|P35240|MERL_HUMAN,sp|P35241|RADI_HUMAN,tr|A0A2R8Y5P0|A0A2R8Y5P0_HUMAN,tr|A0A2R8Y5S7|A0A2R8Y5S7_HUMAN,tr|E7EQR4|E7EQR4_HUMAN,tr|E9PQ82|E9PQ82_HUMAN,tr|A0A5F9ZHA0|A0A5F9ZHA0_HUMAN,tr|A0A2R8Y7M3|A0A2R8Y7M3_HUMAN,tr|E9PNV3|E9PNV3_HUMAN,tr|V9GZ54|V9GZ54_HUMAN" 12 901.5517 0.5 7205 19688 2 901.550757 451.7831 Ezrin OS=Homo sapiens OX=9606 GN=EZR PE=1 SV=4 8.75 3689.8 - 6.08E+06 - - - -1.0182 - 1.305 0.202 - 172.7 1 2 0 -0.0009 7 0 0 0 2.49E+07 4.96E+07 - - - 1.3762 0.9998 221125_WJC_METTL3_EV_vs_WT_F01.19689.19689.2 0.000381 18-Sep K.GIGFLTSGWR[166.11].F sp|Q8IXM3|RM41_HUMAN 1 1102.5799 1.38 7206 19689 2 1102.58 552.2972 "39S ribosomal protein L41, mitochondrial OS=Homo sapiens OX=9606 GN=MRPL41 PE=1 SV=1" 9.75 3689.8 - 5.55E+06 - - - 0.0916 - 1.898 0.449 - 263.3 1 2 0 0.0001 10 0 0 0 5.45E+07 3.95E+07 - - - 4.146 0.9996 221125_WJC_METTL3_EV_vs_WT_F01.19690.19690.2 0.00408 18-Oct R.AAFVLPEFAR[166.11].K "sp|P19623|SPEE_HUMAN,tr|K7EL89|K7EL89_HUMAN" 2 1129.616 0.43 7207 19690 2 1129.6177 565.8153 Spermidine synthase OS=Homo sapiens OX=9606 GN=SRM PE=1 SV=1 6.05 3689.9 - 2.25E+06 - - - 1.5492 - 2.008 0.387 - 336.5 1 2 0 0.0018 10 0 0 0 2.04E+07 4.79E+07 - - - 3.8448 0.9991 221125_WJC_METTL3_EV_vs_WT_F01.19693.19693.2 0.000278 18-Oct R.AAFVLPEFAR.K "sp|P19623|SPEE_HUMAN,tr|K7EL89|K7EL89_HUMAN" 2 1119.6077 0.4 7210 19693 2 1119.608554 560.8111 Spermidine synthase OS=Homo sapiens OX=9606 GN=SRM PE=1 SV=1 6.05 3690.1 - 994820 - - - 0.7806 - 1.818 0.263 - 308.1 1 2 0 0.0009 10 0 0 0 2.04E+07 5.16E+07 - - - 2.6517 0.9965 221125_WJC_METTL3_EV_vs_WT_F01.19694.19694.2 0.736 16-Oct R.NLLGLALGR[166.11].L sp|Q8N5L8|RP25L_HUMAN 1 935.5792 1.08 7211 19694 2 935.580296 468.7969 Ribonuclease P protein subunit p25-like protein OS=Homo sapiens OX=9606 GN=RPP25L PE=1 SV=1 9.75 3690.3 - 979714 - - - 1.2025 - 1.855 0.112 - 359.5 1 2 0 0.0011 9 0 0 0 2.76E+07 2.57E+07 - - - 1.6555 1 221125_WJC_METTL3_EV_vs_WT_F01.19697.19697.2 2.49E-10 14/26 K.FYGPAGPYGIFAGR[166.11].D sp|O15173|PGRC2_HUMAN 1 1481.7331 1.28 7214 19697 2 1481.730386 741.8738 Membrane-associated progesterone receptor component 2 OS=Homo sapiens OX=9606 GN=PGRMC2 PE=1 SV=1 8.59 3690.7 - 493509 - - - -1.835 - 2.333 0.642 - 778.8 1 2 0 -0.0027 14 0 0 0 2.53E+07 1.98E+07 - - - 5.9079 0.9994 221125_WJC_METTL3_EV_vs_WT_F01.19698.19698.2 0.14 16-Sep R.GSLITSLLR.S sp|Q53FA7|QORX_HUMAN 1 958.5811 0.96 7215 19698 2 958.581436 480.2978 Quinone oxidoreductase PIG3 OS=Homo sapiens OX=9606 GN=TP53I3 PE=1 SV=2 9.75 3690.8 - 340949 - - - 0.3182 - 1.919 0.257 - 178.3 1 2 0 0.0003 9 0 0 0 2.12E+06 2.21E+06 - - - 2.8248 0.8 221125_WJC_METTL3_EV_vs_WT_F01.19699.19699.2 8.04 12-May K.GVQINIK[136.11].A "sp|Q12866|MERTK_HUMAN,tr|E9PHX8|E9PHX8_HUMAN" 2 778.4792 0.97 7216 19699 2 778.478358 390.2469 Tyrosine-protein kinase Mer OS=Homo sapiens OX=9606 GN=MERTK PE=1 SV=2 8.75 3690.9 - 304680 - - - -1.1304 - 0.952 0 - 67 2 2 0 -0.0009 7 0 0 0 2.43E+06 2.51E+06 - - - -1.2496 0.9917 221125_WJC_METTL3_EV_vs_WT_F01.19700.19700.2 0.402 14-Aug K.TLMIQLLR[166.11].G "sp|P21127|CD11B_HUMAN,sp|Q9UQ88|CD11A_HUMAN,tr|Q5QPR4|Q5QPR4_HUMAN,tr|A0A0D9SER5|A0A0D9SER5_HUMAN,tr|A0A0D9SEN2|A0A0D9SEN2_HUMAN,tr|Q5QPR3|Q5QPR3_HUMAN,tr|A0A0D9SEI3|A0A0D9SEI3_HUMAN" 7 996.6029 0.83 7217 19700 2 996.603084 499.3087 Cyclin-dependent kinase 11B OS=Homo sapiens OX=9606 GN=CDK11B PE=1 SV=4 9.41 3691.1 - 296939 - - - 0.1425 - 1.337 0.113 - 208.5 1 2 0 0.0001 8 0 0 0 1.43E+06 1.72E+06 - - - 0.7515 0.9979 221125_WJC_METTL3_EV_vs_WT_F01.19705.19705.2 0.232 12-Jul K.LFFLQVK.E "sp|P15311|EZRI_HUMAN,sp|P26038|MOES_HUMAN,sp|P35240|MERL_HUMAN,sp|P35241|RADI_HUMAN,tr|A0A2R8Y5P0|A0A2R8Y5P0_HUMAN,tr|A0A2R8Y5S7|A0A2R8Y5S7_HUMAN,tr|E7EQR4|E7EQR4_HUMAN,tr|E9PQ82|E9PQ82_HUMAN,tr|A0A5F9ZHA0|A0A5F9ZHA0_HUMAN,tr|A0A2R8Y7M3|A0A2R8Y7M3_HUMAN,tr|E9PNV3|E9PNV3_HUMAN,tr|V9GZ54|V9GZ54_HUMAN" 12 893.5375 0.5 7220 19705 2 893.537156 447.776 Ezrin OS=Homo sapiens OX=9606 GN=EZR PE=1 SV=4 8.75 3691.7 - 4.16E+06 - - - -0.357 - 1.522 0.188 - 165 1 2 0 -0.0003 7 0 0 0 2.49E+07 4.96E+07 - - - 1.7603 0.9998 221125_WJC_METTL3_EV_vs_WT_F01.19707.19707.2 0.000754 16-Oct K.SLTYLSILR[166.11].N "sp|P09661|RU2A_HUMAN,tr|H0YMA0|H0YMA0_HUMAN,tr|H0YKK0|H0YKK0_HUMAN" 3 1074.6313 1.07 7222 19707 2 1074.629853 538.3229 U2 small nuclear ribonucleoprotein A' OS=Homo sapiens OX=9606 GN=SNRPA1 PE=1 SV=2 8.46 3691.8 - 2.07E+06 - - - -1.3149 - 2.017 0.454 - 393.9 1 2 0 -0.0014 9 0 0 0 1.39E+07 1.30E+07 - - - 4.4236 0.9996 221125_WJC_METTL3_EV_vs_WT_F01.19708.19708.2 0.000402 16-Oct K.SLTYLSILR.N "sp|P09661|RU2A_HUMAN,tr|H0YMA0|H0YMA0_HUMAN,tr|H0YKK0|H0YKK0_HUMAN" 3 1064.623 1.07 7223 19708 2 1064.624785 533.3188 U2 small nuclear ribonucleoprotein A' OS=Homo sapiens OX=9606 GN=SNRPA1 PE=1 SV=2 8.46 3691.9 - 2.06E+06 - - - 1.6804 - 1.755 0.444 - 409.2 1 2 0 0.0018 9 0 0 0 1.39E+07 1.30E+07 - - - 3.9471 0.9992 221125_WJC_METTL3_EV_vs_WT_F01.19710.19710.2 0.00016 22-Nov K.LTVYTTLIDVTK.G "sp|Q13510|ASAH1_HUMAN,tr|A0A1B0GV06|A0A1B0GV06_HUMAN,tr|A0A1B0GUE3|A0A1B0GUE3_HUMAN,tr|A0A1B0GUH5|A0A1B0GUH5_HUMAN,tr|A0A1B0GUA4|A0A1B0GUA4_HUMAN,tr|A0A1B0GTM3|A0A1B0GTM3_HUMAN,tr|A0A1B0GW68|A0A1B0GW68_HUMAN,tr|A0A1B0GTZ5|A0A1B0GTZ5_HUMAN,tr|A0A1B0GUW4|A0A1B0GUW4_HUMAN,tr|E7EMM4|E7EMM4_HUMAN,tr|A0A1B0GTP7|A0A1B0GTP7_HUMAN,tr|A0A1B0GUG1|A0A1B0GUG1_HUMAN" 12 1365.7755 999 7225 19710 2 1365.771935 683.895 Acid ceramidase OS=Homo sapiens OX=9606 GN=ASAH1 PE=1 SV=5 5.83 3692 - 1.56E+06 - - - -2.6344 - 1.863 0.442 - 274.5 1 2 0 -0.0036 12 0 0 0 6.54E+06 0.00E+00 - - - 3.9416 0.9999 221125_WJC_METTL3_EV_vs_WT_F01.19711.19711.2 8.04E-10 14/26 K.FYGPAGPYGIFAGR.D sp|O15173|PGRC2_HUMAN 1 1471.7248 1.22 7226 19711 2 1471.724253 736.8697 Membrane-associated progesterone receptor component 2 OS=Homo sapiens OX=9606 GN=PGRMC2 PE=1 SV=1 8.59 3692.1 - 1.22E+06 - - - -0.3955 - 2.362 0.528 - 679.7 1 2 0 -0.0006 14 0 0 0 2.54E+07 2.08E+07 - - - 5.0975 1 221125_WJC_METTL3_EV_vs_WT_F01.19714.19714.2 5.21E-06 14/22 K.IYDALDVSLIER[166.11].G sp|P54136|SYRC_HUMAN 1 1415.7536 0.76 7229 19714 2 1415.750766 708.8841 "Arginine--tRNA ligase, cytoplasmic OS=Homo sapiens OX=9606 GN=RARS1 PE=1 SV=2" 4.03 3692.5 - 691165 - - - -1.9777 - 2.768 0.593 - 801.9 1 2 0 -0.0028 12 0 0 0 1.03E+07 1.36E+07 - - - 6.0989 0.9999 221125_WJC_METTL3_EV_vs_WT_F01.19715.19715.2 1.72E-05 22-Dec K.IYDALDVSLIER.G sp|P54136|SYRC_HUMAN 1 1405.7453 0.76 7230 19715 2 1405.74359 703.8799 "Arginine--tRNA ligase, cytoplasmic OS=Homo sapiens OX=9606 GN=RARS1 PE=1 SV=2" 4.03 3692.6 - 495667 - - - -1.2136 - 2.538 0.552 - 501.5 1 2 0 -0.0017 12 0 0 0 1.03E+07 1.36E+07 - - - 5.5681 0.9996 221125_WJC_METTL3_EV_vs_WT_F01.19722.19722.2 2.28E-05 20-Dec K.FDGILGMAYPR.L "sp|P07339|CATD_HUMAN,tr|A0A1B0GW44|A0A1B0GW44_HUMAN,tr|A0A1B0GVD5|A0A1B0GVD5_HUMAN,tr|A0A1B0GV23|A0A1B0GV23_HUMAN,tr|C9JH19|C9JH19_HUMAN,tr|H7C469|H7C469_HUMAN,tr|A0A1B0GWE8|A0A1B0GWE8_HUMAN,tr|A0A1B0GU03|A0A1B0GU03_HUMAN,tr|A0A1B0GVP3|A0A1B0GVP3_HUMAN,tr|F8WD96|F8WD96_HUMAN,tr|A0A1B0GU92|A0A1B0GU92_HUMAN,tr|F8W787|F8W787_HUMAN" 12 1238.6118 7.83 7236 19722 2 1238.608389 620.3132 Cathepsin D OS=Homo sapiens OX=9606 GN=CTSD PE=1 SV=1 5.84 3693.4 - 3.29E+06 - - - -2.7369 - 2.384 0.486 - 663.3 1 2 0 -0.0034 11 0 0 0 2.41E+07 3.08E+06 - - - 4.9798 0.9999 221125_WJC_METTL3_EV_vs_WT_F01.19723.19723.2 6.90E-05 14/20 K.LALDIEIATYR.K "sp|P14136|GFAP_HUMAN,sp|Q6KB66|K2C80_HUMAN,sp|P05787|K2C8_HUMAN,sp|P19013|K2C4_HUMAN,sp|P04264|K2C1_HUMAN,sp|P08729|K2C7_HUMAN,tr|A0A1W2PR46|A0A1W2PR46_HUMAN,tr|A0A1X7SBR3|A0A1X7SBR3_HUMAN,tr|A0A1W2PQU7|A0A1W2PQU7_HUMAN,tr|K7EJU1|K7EJU1_HUMAN,tr|A0A1X7SCE1|A0A1X7SCE1_HUMAN,tr|A0A1W2PRT3|A0A1W2PRT3_HUMAN,tr|A0A1W2PS58|A0A1W2PS58_HUMAN,tr|K7EPI4|K7EPI4_HUMAN" 14 1276.7027 91.53 7237 19723 2 1276.701911 639.3586 Glial fibrillary acidic protein OS=Homo sapiens OX=9606 GN=GFAP PE=1 SV=1 4.37 3693.4 - 4.13E+06 - - - -0.6203 - 2.792 0.418 - 966 1 2 0 -0.0008 11 0 0 0 3.12E+08 3.41E+06 - - - 4.9057 0.9998 221125_WJC_METTL3_EV_vs_WT_F01.19727.19727.2 7.91E-06 20-Nov R.QPVGFVIFDSR.A sp|Q6ZRY4|RBPS2_HUMAN 1 1263.6612 0.66 7241 19727 2 1263.659727 632.8379 RNA-binding protein with multiple splicing 2 OS=Homo sapiens OX=9606 GN=RBPMS2 PE=1 SV=1 5.84 3693.9 - 868318 - - - -1.1435 - 1.92 0.481 - 394.4 1 2 0 -0.0014 11 0 0 0 4.84E+06 7.29E+06 - - - 4.3579 0.9998 221125_WJC_METTL3_EV_vs_WT_F01.19731.19731.2 0.00241 18-Oct K.ALELNMLSLK[136.11].G sp|Q9Y617|SERC_HUMAN 1 1138.6511 0.001 7245 19731 2 1138.650651 570.3328 Phosphoserine aminotransferase OS=Homo sapiens OX=9606 GN=PSAT1 PE=1 SV=2 6.05 3694.4 - 663583 - - - -0.4216 - 2.203 0.406 - 304.5 1 2 0 -0.0005 10 0 0 0 0.00E+00 5.27E+06 - - - 4.2442 0.9996 221125_WJC_METTL3_EV_vs_WT_F01.19732.19732.2 6.49E-05 20-Sep K.FDGILGMAYPR[166.11].L "sp|P07339|CATD_HUMAN,tr|A0A1B0GW44|A0A1B0GW44_HUMAN,tr|A0A1B0GVD5|A0A1B0GVD5_HUMAN,tr|A0A1B0GV23|A0A1B0GV23_HUMAN,tr|C9JH19|C9JH19_HUMAN,tr|H7C469|H7C469_HUMAN,tr|A0A1B0GWE8|A0A1B0GWE8_HUMAN,tr|A0A1B0GU03|A0A1B0GU03_HUMAN,tr|A0A1B0GVP3|A0A1B0GVP3_HUMAN,tr|F8WD96|F8WD96_HUMAN,tr|A0A1B0GU92|A0A1B0GU92_HUMAN,tr|F8W787|F8W787_HUMAN" 12 1248.62 -1 7246 19732 2 1248.622367 625.3173 Cathepsin D OS=Homo sapiens OX=9606 GN=CTSD PE=1 SV=1 5.84 3694.5 - 495318 - - - 1.8564 - 2.066 0.406 - 243.4 1 2 0 0.0023 11 0 0 0 0.00E+00 0.00E+00 - - - 4.0019 0.9971 221125_WJC_METTL3_EV_vs_WT_F01.19734.19734.2 0.000674 22-Nov K.LGEAAVLEIVER[166.11].L "sp|Q92485|ASM3B_HUMAN,tr|Q5T0Y8|Q5T0Y8_HUMAN,tr|F8VWW8|F8VWW8_HUMAN" 3 1307.7324 1.77 7248 19734 2 1307.738478 654.8735 Acid sphingomyelinase-like phosphodiesterase 3b OS=Homo sapiens OX=9606 GN=SMPDL3B PE=1 SV=2 4.25 3694.7 - 315224 - - - 4.6202 - 2.308 0.392 - 350.1 1 2 0 0.006 12 0 0 0 4.68E+06 2.64E+06 - - - 4.1351 0.9999 221125_WJC_METTL3_EV_vs_WT_F01.19737.19737.2 0.00646 14/24 K.LDNLLLDTEGYVK.L "sp|Q16512|PKN1_HUMAN,tr|K7EL10|K7EL10_HUMAN" 2 1491.7821 1.91 7251 19737 2 1491.783647 746.8983 Serine\threonine-protein kinase N1 OS=Homo sapiens OX=9606 GN=PKN1 PE=1 SV=2 4.03 3695.1 - 289511 - - - 1.0538 - 2.929 0.492 - 748.1 1 2 0 0.0016 13 0 0 0 4.38E+06 2.30E+06 - - - 5.4326 0.9997 221125_WJC_METTL3_EV_vs_WT_F01.19739.19739.2 0.00523 28-Sep K.LLMADQDSPLDLTVR.K "sp|Q96JN0|LCOR_HUMAN,tr|A0A6Q8PH28|A0A6Q8PH28_HUMAN,tr|A0A6Q8PG83|A0A6Q8PG83_HUMAN,tr|A0A6Q8PFQ9|A0A6Q8PFQ9_HUMAN,tr|A0A6Q8PGR8|A0A6Q8PGR8_HUMAN,tr|A0A6Q8PGL8|A0A6Q8PGL8_HUMAN,tr|A0A6Q8PFM9|A0A6Q8PFM9_HUMAN,tr|A0A6Q8PGP3|A0A6Q8PGP3_HUMAN" 8 1685.8658 0.43 7253 19739 2 1685.865153 843.9402 Ligand-dependent corepressor OS=Homo sapiens OX=9606 GN=LCOR PE=1 SV=2 3.93 3695.4 - 183182 - - - -0.3968 - 1.897 0.427 - 179.5 1 2 0 -0.0007 15 0 0 0 1.26E+06 2.96E+06 - - - 3.7688 0.9995 221125_WJC_METTL3_EV_vs_WT_F01.19745.19745.2 7.80E-05 16-Sep R.MLFDYLADK.H "sp|P60228|EIF3E_HUMAN,tr|A0A7I2V3I2|A0A7I2V3I2_HUMAN,tr|A0A7I2V570|A0A7I2V570_HUMAN,tr|A0A7I2V2Q9|A0A7I2V2Q9_HUMAN,tr|H0YBP5|H0YBP5_HUMAN,tr|A0A7I2V5Z6|A0A7I2V5Z6_HUMAN,tr|A0A7I2V2H9|A0A7I2V2H9_HUMAN,tr|B3KW56|B3KW56_HUMAN,tr|A0A7I2V4B4|A0A7I2V4B4_HUMAN,tr|E5RGA2|E5RGA2_HUMAN,tr|A0A7I2V3I0|A0A7I2V3I0_HUMAN,tr|A0A7I2V3S3|A0A7I2V3S3_HUMAN,tr|A0A7I2V4G3|A0A7I2V4G3_HUMAN,tr|A0A7I2V5K7|A0A7I2V5K7_HUMAN,tr|A0A7I2V3W9|A0A7I2V3W9_HUMAN,tr|H0YBR5|H0YBR5_HUMAN,tr|A0A7I2V429|A0A7I2V429_HUMAN,tr|A0A7I2V2W0|A0A7I2V2W0_HUMAN,tr|A0A7I2V5P9|A0A7I2V5P9_HUMAN,tr|A0A161SXE1|A0A161SXE1_HUMAN" 20 1114.5369 0.33 7257 19745 2 1114.534097 558.2757 Eukaryotic translation initiation factor 3 subunit E OS=Homo sapiens OX=9606 GN=EIF3E PE=1 SV=1 4.21 3696 - 2.61E+06 - - - -2.4997 - 1.806 0.483 - 232.2 1 2 0 -0.0028 9 0 0 0 1.57E+07 4.74E+07 - - - 4.3177 1 221125_WJC_METTL3_EV_vs_WT_F01.19746.19746.2 1.24E-08 15/28 R.LYGPSSVSFADDFVR.S "sp|P50454|SERPH_HUMAN,tr|E9PNX1|E9PNX1_HUMAN,tr|E9PIG2|E9PIG2_HUMAN,tr|E9PPV6|E9PPV6_HUMAN,tr|E9PR70|E9PR70_HUMAN,tr|E9PMI5|E9PMI5_HUMAN,tr|E9PRS3|E9PRS3_HUMAN,tr|E9PJH8|E9PJH8_HUMAN,tr|E9PK86|E9PK86_HUMAN,tr|E9PQ34|E9PQ34_HUMAN" 10 1658.794 1.58 7258 19746 2 1658.794528 830.4043 Serpin H1 OS=Homo sapiens OX=9606 GN=SERPINH1 PE=1 SV=2 4.21 3696.1 - 2.23E+06 - - - 0.296 - 2.863 0.702 - 634.5 1 2 0 0.0005 15 0 0 0 1.65E+07 1.04E+07 - - - 6.8119 1 221125_WJC_METTL3_EV_vs_WT_F01.19747.19747.2 2.40E-06 13/24 R.SLVWGAEAVQALR.E "sp|Q9BSV6|SEN34_HUMAN,tr|A0A590UJ73|A0A590UJ73_HUMAN,tr|E7EQB3|E7EQB3_HUMAN,tr|A0A0G2JNK5|A0A0G2JNK5_HUMAN,tr|A0A0G2JNL0|A0A0G2JNL0_HUMAN,tr|A0A590UJW4|A0A590UJW4_HUMAN,tr|B0V3J0|B0V3J0_HUMAN" 7 1398.7619 1.52 7259 19747 2 1398.763691 700.3883 tRNA-splicing endonuclease subunit Sen34 OS=Homo sapiens OX=9606 GN=TSEN34 PE=1 SV=1 5.72 3696.1 - 1.81E+06 - - - 1.2454 - 2.646 0.575 - 631.7 1 2 0 0.0017 13 0 0 0 1.33E+07 8.78E+06 - - - 5.7848 0.9997 221125_WJC_METTL3_EV_vs_WT_F01.19749.19749.2 9.68E-06 18-Nov R.QEVVDLLLAR.G "sp|Q8IWZ3|ANKH1_HUMAN,tr|E9PDP5|E9PDP5_HUMAN,tr|H3BLS9|H3BLS9_HUMAN,tr|H7C2F5|H7C2F5_HUMAN" 4 1154.6659 1.32 7261 19749 2 1154.668939 578.3402 Ankyrin repeat and KH domain-containing protein 1 OS=Homo sapiens OX=9606 GN=ANKHD1 PE=1 SV=1 4.37 3696.3 - 1.39E+06 - - - 2.612 - 2.394 0.551 - 659.4 1 2 0 0.003 10 0 0 0 9.82E+07 7.41E+07 - - - 5.5465 0.9985 221125_WJC_METTL3_EV_vs_WT_F01.19750.19750.2 1.67E-05 18-Nov R.QEVVDLLLAR[166.11].G "sp|Q8IWZ3|ANKH1_HUMAN,tr|E9PDP5|E9PDP5_HUMAN,tr|H3BLS9|H3BLS9_HUMAN,tr|H7C2F5|H7C2F5_HUMAN" 4 1164.6742 1.32 7262 19750 2 1164.679705 583.3444 Ankyrin repeat and KH domain-containing protein 1 OS=Homo sapiens OX=9606 GN=ANKHD1 PE=1 SV=1 4.37 3696.4 - 1.28E+06 - - - 4.7327 - 2.411 0.538 - 682.3 1 2 0 0.0055 10 0 0 0 9.82E+07 7.41E+07 - - - 5.4694 1 221125_WJC_METTL3_EV_vs_WT_F01.19751.19751.2 3.49E-11 13/20 R.PMEVFMC[160.03]SVLK.R "sp|Q9NR31|SAR1A_HUMAN,tr|H0Y5E8|H0Y5E8_HUMAN" 2 1339.6338 1.05 7263 19751 2 1339.634057 670.8242 GTP-binding protein SAR1a OS=Homo sapiens OX=9606 GN=SAR1A PE=1 SV=1 6.38 3696.5 - 1.26E+06 - - - 0.1642 - 2.683 0.675 - 627.6 1 1 0 0.0002 11 0 0 0 2.36E+07 2.25E+07 - - - 6.6964 0.9999 221125_WJC_METTL3_EV_vs_WT_F01.19753.19753.2 7.22E-06 15/24 R.SLVWGAEAVQALR[166.11].E "sp|Q9BSV6|SEN34_HUMAN,tr|A0A590UJ73|A0A590UJ73_HUMAN,tr|E7EQB3|E7EQB3_HUMAN,tr|A0A0G2JNK5|A0A0G2JNK5_HUMAN,tr|A0A0G2JNL0|A0A0G2JNL0_HUMAN,tr|A0A590UJW4|A0A590UJW4_HUMAN,tr|B0V3J0|B0V3J0_HUMAN" 7 1408.7702 1.52 7265 19753 2 1408.770895 705.3924 tRNA-splicing endonuclease subunit Sen34 OS=Homo sapiens OX=9606 GN=TSEN34 PE=1 SV=1 5.72 3696.7 - 1.02E+06 - - - 0.4799 - 3.194 0.488 - 839 1 2 0 0.0007 13 0 0 0 1.33E+07 8.78E+06 - - - 5.6256 0.9996 221125_WJC_METTL3_EV_vs_WT_F01.19754.19754.2 0.00182 28-Sep R.LTPSASLPPAQLLLR.A "sp|P06576|ATPB_HUMAN,tr|F8W079|F8W079_HUMAN,tr|F8W0P7|F8W0P7_HUMAN,tr|H0YH81|H0YH81_HUMAN" 4 1575.9348 2.66 7266 19754 2 1575.935665 788.9747 "ATP synthase subunit beta, mitochondrial OS=Homo sapiens OX=9606 GN=ATP5F1B PE=1 SV=3" 9.75 3696.8 - 936602 - - - 0.5311 - 1.707 0.407 - 95.5 1 2 0 0.0008 15 0 0 0 2.77E+07 1.04E+07 - - - 3.3615 0.9995 221125_WJC_METTL3_EV_vs_WT_F01.19755.19755.2 0.0093 16-Aug K.DAIDPLLFK.Y sp|Q9NRL2|BAZ1A_HUMAN 1 1030.5699 1.43 7267 19755 2 1030.569658 516.2922 Bromodomain adjacent to zinc finger domain protein 1A OS=Homo sapiens OX=9606 GN=BAZ1A PE=1 SV=2 4.21 3696.9 - 921452 - - - -0.2329 - 1.594 0.36 - 151 1 2 0 -0.0002 9 0 0 0 5.32E+06 3.73E+06 - - - 3.0488 0.993 221125_WJC_METTL3_EV_vs_WT_F01.19756.19756.2 0.0291 16-Jul K.DAIDPLLFK[136.11].Y sp|Q9NRL2|BAZ1A_HUMAN 1 1038.5841 1.41 7268 19756 2 1038.579701 520.2993 Bromodomain adjacent to zinc finger domain protein 1A OS=Homo sapiens OX=9606 GN=BAZ1A PE=1 SV=2 4.21 3697 - 828043 - - - -4.2336 - 1.711 0.296 - 119.5 1 2 0 -0.0044 9 0 0 0 5.16E+06 3.66E+06 - - - 2.7797 0.9999 221125_WJC_METTL3_EV_vs_WT_F01.19759.19759.3 0.000188 14/40 K.LALDIEIATYR.K "sp|P14136|GFAP_HUMAN,sp|Q6KB66|K2C80_HUMAN,sp|P05787|K2C8_HUMAN,sp|P19013|K2C4_HUMAN,sp|P04264|K2C1_HUMAN,sp|P08729|K2C7_HUMAN,tr|A0A1W2PR46|A0A1W2PR46_HUMAN,tr|A0A1X7SBR3|A0A1X7SBR3_HUMAN,tr|A0A1W2PQU7|A0A1W2PQU7_HUMAN,tr|K7EJU1|K7EJU1_HUMAN,tr|A0A1X7SCE1|A0A1X7SCE1_HUMAN,tr|A0A1W2PRT3|A0A1W2PRT3_HUMAN,tr|A0A1W2PS58|A0A1W2PS58_HUMAN,tr|K7EPI4|K7EPI4_HUMAN" 14 1276.7027 96 7271 19759 3 1276.703569 426.5748 Glial fibrillary acidic protein OS=Homo sapiens OX=9606 GN=GFAP PE=1 SV=1 4.37 3697.4 - 605439 - - - 0.6783 - 2.65 0.352 - 342.9 1 2 0 0.0009 11 0 0 0 7.49E+06 7.80E+04 - - - 5.2328 0.9996 221125_WJC_METTL3_EV_vs_WT_F01.19761.19761.2 1.70E-06 14/24 R.AGLNGLQLAVLAR[166.11].L sp|Q96S55|WRIP1_HUMAN 1 1304.7804 0.73 7273 19761 2 1304.781056 653.3975 ATPase WRNIP1 OS=Homo sapiens OX=9606 GN=WRNIP1 PE=1 SV=2 9.79 3697.7 - 525364 - - - 0.5104 - 2.913 0.228 - 747.2 1 2 0 0.0007 13 0 0 0 2.05E+06 2.81E+06 - - - 3.4689 0.9999 221125_WJC_METTL3_EV_vs_WT_F01.19767.19767.2 0.000396 16-Oct K.YDWDLLAAR.S "sp|Q15029|U5S1_HUMAN,tr|K7EJ74|K7EJ74_HUMAN,tr|K7EP67|K7EP67_HUMAN" 3 1121.5506 2.04 7278 19767 2 1121.550653 561.7826 116 kDa U5 small nuclear ribonucleoprotein component OS=Homo sapiens OX=9606 GN=EFTUD2 PE=1 SV=1 4.21 3698.3 - 1.34E+07 - - - 0.0838 - 1.979 0.501 - 376.5 1 2 0 0.0001 9 0 0 0 6.79E+07 3.33E+07 - - - 4.7161 0.9991 221125_WJC_METTL3_EV_vs_WT_F01.19768.19768.2 0.031 14-Aug R.DWVLNEFK.H "sp|P17844|DDX5_HUMAN,tr|A0A7I2V5F5|A0A7I2V5F5_HUMAN,tr|A0A7I2V507|A0A7I2V507_HUMAN,tr|J3KTA4|J3KTA4_HUMAN,tr|A0A0G2JLI4|A0A0G2JLI4_HUMAN,tr|A0A7I2V2S0|A0A7I2V2S0_HUMAN" 6 1049.5182 1.59 7279 19768 2 1049.518487 525.7664 Probable ATP-dependent RNA helicase DDX5 OS=Homo sapiens OX=9606 GN=DDX5 PE=1 SV=1 4.37 3698.4 - 1.11E+07 - - - 0.2773 - 1.555 0.29 - 286.3 1 2 0 0.0003 8 0 0 0 1.60E+08 1.01E+08 - - - 2.5143 0.9989 221125_WJC_METTL3_EV_vs_WT_F01.19769.19769.2 0.0119 14-Jul R.DWVLNEFK[136.11].H "sp|P17844|DDX5_HUMAN,tr|A0A7I2V5F5|A0A7I2V5F5_HUMAN,tr|A0A7I2V507|A0A7I2V507_HUMAN,tr|J3KTA4|J3KTA4_HUMAN,tr|A0A0G2JLI4|A0A0G2JLI4_HUMAN,tr|A0A7I2V2S0|A0A7I2V2S0_HUMAN" 6 1057.5324 1.59 7280 19769 2 1057.532681 529.7735 Probable ATP-dependent RNA helicase DDX5 OS=Homo sapiens OX=9606 GN=DDX5 PE=1 SV=1 4.37 3698.4 - 8.19E+06 - - - 0.2695 - 1.42 0.301 - 201.7 1 2 0 0.0003 8 0 0 0 1.60E+08 1.01E+08 - - - 2.3217 0.9996 221125_WJC_METTL3_EV_vs_WT_F01.19770.19770.2 0.0099 12-Aug R.FELFVMK[136.11].K sp|Q15046|SYK_HUMAN 1 920.4921 0.54 7281 19770 2 920.491351 461.2533 Lysine--tRNA ligase OS=Homo sapiens OX=9606 GN=KARS1 PE=1 SV=3 6 3698.4 - 3.97E+06 - - - -0.8256 - 1.682 0.352 - 209.2 1 2 0 -0.0008 7 0 0 0 7.90E+06 1.47E+07 - - - 3.2882 0.9993 221125_WJC_METTL3_EV_vs_WT_F01.19771.19771.2 0.00999 12-Aug R.FELFVMK.K sp|Q15046|SYK_HUMAN 1 912.4779 0.53 7282 19771 2 912.475728 457.2462 Lysine--tRNA ligase OS=Homo sapiens OX=9606 GN=KARS1 PE=1 SV=3 6 3698.5 - 2.37E+06 - - - -2.3924 - 1.658 0.424 - 207.4 1 2 0 -0.0022 7 0 0 0 7.72E+06 1.47E+07 - - - 3.774 0.9907 221125_WJC_METTL3_EV_vs_WT_F01.19772.19772.2 0.0024 20-Nov R.IFGGLDMLAEK[136.11].L sp|Q92688|AN32B_HUMAN 1 1200.6304 0.44 7283 19772 2 1200.628085 601.3225 Acidic leucine-rich nuclear phosphoprotein 32 family member B OS=Homo sapiens OX=9606 GN=ANP32B PE=1 SV=1 4.37 3698.6 - 1.67E+06 - - - -1.9248 - 1.774 0.078 - 230.9 1 2 0 -0.0023 11 0 0 0 4.63E+06 1.05E+07 - - - 1.1671 0.9918 221125_WJC_METTL3_EV_vs_WT_F01.19773.19773.2 0.00425 16-Sep R.LTSFITVFK[136.11].Y "sp|Q13617|CUL2_HUMAN,tr|Q5T2B5|Q5T2B5_HUMAN,tr|A0A0A0MTN0|A0A0A0MTN0_HUMAN" 3 1062.6205 0.48 7284 19773 2 1062.625252 532.3175 Cullin-2 OS=Homo sapiens OX=9606 GN=CUL2 PE=1 SV=2 8.75 3698.6 - 1.38E+06 - - - 4.488 - 2.013 0.24 - 218.2 1 2 0 0.0048 9 0 0 0 3.57E+06 7.43E+06 - - - 2.8362 0.9996 221125_WJC_METTL3_EV_vs_WT_F01.19775.19775.2 0.000333 20-Aug R.VFSWGFGGYGR.L sp|Q9P258|RCC2_HUMAN 1 1231.5774 0.7 7286 19775 2 1231.57771 616.796 Protein RCC2 OS=Homo sapiens OX=9606 GN=RCC2 PE=1 SV=2 8.72 3698.8 - 933460 - - - 0.2168 - 1.39 0.437 - 140.6 1 2 0 0.0003 11 0 0 0 4.74E+06 6.80E+06 - - - 3.1594 0.9996 221125_WJC_METTL3_EV_vs_WT_F01.19776.19776.2 0.0124 20-Nov K.IIADIFEYTAK.H sp|P22033|MUTA_HUMAN 1 1282.6809 1.39 7287 19776 2 1282.680978 642.3477 "Methylmalonyl-CoA mutase, mitochondrial OS=Homo sapiens OX=9606 GN=MMUT PE=1 SV=4" 4.37 3698.9 - 1.59E+06 - - - 0.0569 - 2.273 0.261 - 281.2 1 2 0 0.0001 11 0 0 0 5.26E+06 3.79E+06 - - - 3.19 0.9999 221125_WJC_METTL3_EV_vs_WT_F01.19777.19777.2 6.05E-07 15/24 R.VETPVLPPVLVPR[166.11].H "sp|O15198|SMAD9_HUMAN,sp|Q15796|SMAD2_HUMAN,sp|P84022|SMAD3_HUMAN,tr|H3BVD1|H3BVD1_HUMAN,tr|H0YMP2|H0YMP2_HUMAN,tr|K7EJX0|K7EJX0_HUMAN,tr|H3BP09|H3BP09_HUMAN,tr|B7Z5N5|B7Z5N5_HUMAN,tr|H0YL71|H0YL71_HUMAN" 9 1424.8631 1.32 7288 19777 2 1424.864999 713.4388 Mothers against decapentaplegic homolog 9 OS=Homo sapiens OX=9606 GN=SMAD9 PE=1 SV=1 5.97 3699 - 735340 - - - 1.3629 - 2.507 0.572 - 574.9 1 2 0 0.0019 13 0 0 0 2.59E+07 1.97E+07 - - - 5.624 0.9989 221125_WJC_METTL3_EV_vs_WT_F01.19778.19778.2 0.00508 28-Jun R.LTPSASLPPAQLLLR[166.11].A "sp|P06576|ATPB_HUMAN,tr|F8W079|F8W079_HUMAN,tr|F8W0P7|F8W0P7_HUMAN,tr|H0YH81|H0YH81_HUMAN" 4 1585.9431 2.64 7289 19778 2 1585.943211 793.9788 "ATP synthase subunit beta, mitochondrial OS=Homo sapiens OX=9606 GN=ATP5F1B PE=1 SV=3" 9.75 3699.1 - 686552 - - - 0.0713 - 1.488 0.344 - 29.4 4 2 0 0.0001 15 0 0 0 2.83E+07 1.07E+07 - - - 2.2899 0.9999 221125_WJC_METTL3_EV_vs_WT_F01.19781.19781.2 6.96E-06 15/24 R.AIVFVVDSAAFQR[166.11].E "sp|Q9Y5M8|SRPRB_HUMAN,tr|H7C4H2|H7C4H2_HUMAN" 2 1431.775 1.48 7292 19781 2 1431.774077 716.8948 Signal recognition particle receptor subunit beta OS=Homo sapiens OX=9606 GN=SRPRB PE=1 SV=3 5.88 3699.5 - 562878 - - - -0.6237 - 2.896 0.525 - 862.7 1 2 0 -0.0009 13 0 0 0 3.50E+06 2.36E+06 - - - 5.6474 0.9998 221125_WJC_METTL3_EV_vs_WT_F01.19786.19786.2 0.00285 16-Sep R.YLDVSILGK[136.11].F sp|Q86U44|MTA70_HUMAN 1 1014.5841 0.23 7296 19786 2 1014.583552 508.2993 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 5.83 3700.1 - 1.34E+06 - - - -0.5382 - 1.844 0.421 - 184.3 1 2 0 -0.0005 9 0 0 0 4.72E+06 2.02E+07 - - - 3.9207 0.9994 221125_WJC_METTL3_EV_vs_WT_F01.19788.19788.2 0.1 18-Oct K.ISLLTDSLLK.V "sp|Q5VT06|CE350_HUMAN,tr|H0Y7F7|H0Y7F7_HUMAN,tr|Q5T2X4|Q5T2X4_HUMAN" 3 1101.6645 3.97 7298 19788 2 1101.663095 551.8395 Centrosome-associated protein 350 OS=Homo sapiens OX=9606 GN=CEP350 PE=1 SV=1 5.84 3700.3 - 2.33E+06 - - - -1.2989 - 1.976 0.312 - 188.4 1 2 0 -0.0014 10 0 0 0 1.35E+07 3.39E+06 - - - 3.2461 0.9998 221125_WJC_METTL3_EV_vs_WT_F01.19791.19791.2 0.0012 18-Oct R.LAEVWMDEFK.N "sp|Q10472|GALT1_HUMAN,sp|Q8IUC8|GLT13_HUMAN,tr|K7EJV8|K7EJV8_HUMAN" 3 1266.5955 1.68 7301 19791 2 1266.596839 634.305 Polypeptide N-acetylgalactosaminyltransferase 1 OS=Homo sapiens OX=9606 GN=GALNT1 PE=1 SV=1 4.14 3700.5 - 1.59E+06 - - - 1.0887 - 2.22 0.412 - 424.5 1 2 0 0.0014 10 0 0 0 9.81E+06 5.82E+06 - - - 4.3097 0.9995 221125_WJC_METTL3_EV_vs_WT_F01.19792.19792.2 0.00192 14-Aug K.AIFLFVDK[136.11].T "sp|P60520|GBRL2_HUMAN,tr|H3BQ50|H3BQ50_HUMAN,tr|H3BSM5|H3BSM5_HUMAN" 3 959.5572 0.97 7302 19792 2 959.557051 480.7859 Gamma-aminobutyric acid receptor-associated protein-like 2 OS=Homo sapiens OX=9606 GN=GABARAPL2 PE=1 SV=1 5.88 3700.6 - 1.53E+06 - - - -0.1073 - 1.512 0.361 - 238.6 1 2 0 -0.0001 8 0 0 0 1.35E+07 1.39E+07 - - - 2.9542 0.999 221125_WJC_METTL3_EV_vs_WT_F01.19794.19794.2 0.000213 18-Oct K.LIPVPMVGFK[136.11].E sp|Q7Z3B4|NUP54_HUMAN 1 1107.6606 4.1 7304 19794 2 1107.664641 554.8376 Nucleoporin p54 OS=Homo sapiens OX=9606 GN=NUP54 PE=1 SV=2 8.75 3700.8 - 1.41E+06 - - - 3.6717 - 1.942 0.519 - 248.3 1 2 0 0.0041 10 0 0 0 1.39E+08 3.40E+07 - - - 4.7257 0.9998 221125_WJC_METTL3_EV_vs_WT_F01.19795.19795.2 1.53E-05 24-Nov R.VETPVLPPVLVPR.H "sp|O15198|SMAD9_HUMAN,sp|Q15796|SMAD2_HUMAN,sp|P84022|SMAD3_HUMAN,tr|H3BVD1|H3BVD1_HUMAN,tr|H0YMP2|H0YMP2_HUMAN,tr|K7EJX0|K7EJX0_HUMAN,tr|H3BP09|H3BP09_HUMAN,tr|B7Z5N5|B7Z5N5_HUMAN,tr|H0YL71|H0YL71_HUMAN" 9 1414.8548 1.32 7305 19795 2 1414.853077 708.4347 Mothers against decapentaplegic homolog 9 OS=Homo sapiens OX=9606 GN=SMAD9 PE=1 SV=1 5.97 3700.8 - 1.34E+06 - - - -1.2086 - 2.083 0.526 - 302 1 2 0 -0.0017 13 0 0 0 2.59E+07 1.97E+07 - - - 4.8088 0.9978 221125_WJC_METTL3_EV_vs_WT_F01.19796.19796.2 0.3 14-Jul K.AIFLFVDK.T "sp|P60520|GBRL2_HUMAN,tr|H3BQ50|H3BQ50_HUMAN,tr|H3BSM5|H3BSM5_HUMAN" 3 951.543 0.99 7306 19796 2 951.54119 476.7788 Gamma-aminobutyric acid receptor-associated protein-like 2 OS=Homo sapiens OX=9606 GN=GABARAPL2 PE=1 SV=1 5.88 3700.9 - 1.33E+06 - - - -1.8538 - 1.524 0.263 - 160.5 1 2 0 -0.0018 8 0 0 0 1.30E+07 1.32E+07 - - - 2.2537 0.9991 221125_WJC_METTL3_EV_vs_WT_F01.19800.19800.2 0.273 20-Sep R.IAIQGIITAIK.Y sp|Q6NSI4|RADX_HUMAN 1 1139.7278 0.81 7310 19800 2 1139.729707 570.8712 RPA-related protein RADX OS=Homo sapiens OX=9606 GN=RADX PE=1 SV=2 8.75 3701.3 - 573017 - - - 1.6776 - 1.937 0.304 - 137.6 1 2 0 0.0019 11 0 0 0 1.67E+06 2.06E+06 - - - 3.0743 0.8583 221125_WJC_METTL3_EV_vs_WT_F01.19801.19801.2 8.85 16-Jun K.AFLFDVVSK.L "sp|Q9NQL2|RRAGD_HUMAN,sp|Q9HB90|RRAGC_HUMAN" 2 1024.5593 1.56 7311 19801 2 1024.560391 513.2869 Ras-related GTP-binding protein D OS=Homo sapiens OX=9606 GN=RRAGD PE=1 SV=1 5.88 3701.5 - 498259 - - - 1.0326 - 0.92 0.051 - 56.4 2 2 0 0.0011 9 0 0 0 2.52E+06 1.61E+06 - - - -0.9583 0.8651 221125_WJC_METTL3_EV_vs_WT_F01.19802.19802.2 0.674 14-Sep H.LWDLLEGK.E "sp|Q14444|CAPR1_HUMAN,tr|G3V153|G3V153_HUMAN" 2 972.528 1.15 7312 19802 2 972.527982 487.2713 Caprin-1 OS=Homo sapiens OX=9606 GN=CAPRIN1 PE=1 SV=2 4.37 3701.6 - 412332 - - - -0.0524 - 1.683 0.132 - 218.4 1 1 0 -0.0001 8 0 0 0 1.70E+06 1.48E+06 - - - 1.586 0.9996 221125_WJC_METTL3_EV_vs_WT_F01.19803.19803.2 2.82E-09 30-Nov R.FGPYYTEPVIAGLDPK.T "sp|P49720|PSB3_HUMAN,tr|A0A087WUL2|A0A087WUL2_HUMAN" 2 1765.8927 0.79 7313 19803 2 1765.886935 883.9536 Proteasome subunit beta type-3 OS=Homo sapiens OX=9606 GN=PSMB3 PE=1 SV=2 4.37 3701.7 - 405859 - - - -3.2578 - 2.189 0.637 - 258.1 1 2 0 -0.0058 16 0 0 0 4.60E+06 5.80E+06 - - - 5.6702 1 221125_WJC_METTL3_EV_vs_WT_F01.19804.19804.2 2.07E-12 15/30 R.FGPYYTEPVIAGLDPK[136.11].T "sp|P49720|PSB3_HUMAN,tr|A0A087WUL2|A0A087WUL2_HUMAN" 2 1773.9069 0.79 7314 19804 2 1773.904328 887.9607 Proteasome subunit beta type-3 OS=Homo sapiens OX=9606 GN=PSMB3 PE=1 SV=2 4.37 3701.9 - 356157 - - - -1.4431 - 2.599 0.65 - 537.3 1 2 0 -0.0026 16 0 0 0 4.60E+06 5.80E+06 - - - 6.1893 1 221125_WJC_METTL3_EV_vs_WT_F01.19807.19807.2 1.02E-08 20-Oct R.PMEVFMC[160.03]SVLK[136.11].R "sp|Q9NR31|SAR1A_HUMAN,tr|H0Y5E8|H0Y5E8_HUMAN" 2 1347.648 1.05 7316 19807 2 1347.646737 674.8313 GTP-binding protein SAR1a OS=Homo sapiens OX=9606 GN=SAR1A PE=1 SV=1 6.38 3702.2 - 2.35E+06 - - - -0.9646 - 2.361 0.65 - 307.6 1 1 0 -0.0013 11 0 0 0 2.36E+07 2.25E+07 - - - 6.1655 0.9997 221125_WJC_METTL3_EV_vs_WT_F01.19809.19809.2 0.000731 18-Aug K.YFSSMAEFLK.V "sp|Q8WWY3|PRP31_HUMAN,tr|E7EVX8|E7EVX8_HUMAN" 2 1221.574 2.32 7318 19809 2 1221.575309 611.7943 U4\U6 small nuclear ribonucleoprotein Prp31 OS=Homo sapiens OX=9606 GN=PRPF31 PE=1 SV=2 6 3702.3 - 1.57E+07 - - - 1.074 - 1.662 0.496 - 129.3 1 2 0 0.0013 10 0 0 0 1.05E+08 4.51E+07 - - - 4.1221 0.9998 221125_WJC_METTL3_EV_vs_WT_F01.19811.19811.2 0.0158 20-Dec R.TLVLLDNLNVR.E "sp|P39656|OST48_HUMAN,tr|U3KQ84|U3KQ84_HUMAN,tr|A0A0C4DGS1|A0A0C4DGS1_HUMAN" 3 1268.7452 1.41 7320 19811 2 1268.746601 635.3799 Dolichyl-diphosphooligosaccharide--protein glycosyltransferase 48 kDa subunit OS=Homo sapiens OX=9606 GN=DDOST PE=1 SV=4 5.5 3702.4 - 5.58E+06 - - - 1.0759 - 2.548 0.448 - 599.5 1 2 0 0.0014 11 0 0 0 8.45E+07 6.01E+07 - - - 4.8797 0.7915 221125_WJC_METTL3_EV_vs_WT_F01.19812.19812.2 0.0541 18-Jul H.DLLLLQLSEK.A "sp|P00746|CFAD_HUMAN,tr|K7ERG9|K7ERG9_HUMAN" 2 1170.686 15.56 7321 19812 2 1170.686889 586.3503 Complement factor D OS=Homo sapiens OX=9606 GN=CFD PE=1 SV=5 4.37 3702.5 - 2.58E+06 - - - 0.7679 - 1.739 0.101 - 146.3 1 1 0 0.0009 10 0 0 0 1.23E+07 7.88E+05 - - - 1.3312 0.7706 221125_WJC_METTL3_EV_vs_WT_F01.19813.19813.2 2.69 20-Jul K.FNIFYPDLIDK.R "sp|Q8WUQ7|CATIN_HUMAN,tr|K7EIU6|K7EIU6_HUMAN,tr|K7ENY9|K7ENY9_HUMAN" 3 1383.7075 -1 7322 19813 2 1383.720323 692.861 Cactin OS=Homo sapiens OX=9606 GN=CACTIN PE=1 SV=3 4.21 3702.5 - 1.68E+06 - - - 9.3004 - 2.098 0.124 - 173.2 4 2 0 0.0129 11 0 0 0 0.00E+00 0.00E+00 - - - 1.6884 0.965 221125_WJC_METTL3_EV_vs_WT_F01.19814.19814.2 1.69 12-Jun R.TLLEFLK[136.11].R "sp|Q14232|EI2BA_HUMAN,tr|F5H0D0|F5H0D0_HUMAN,tr|H0YGG4|H0YGG4_HUMAN" 3 870.5306 0.99 7323 19814 2 870.532151 436.2726 Translation initiation factor eIF-2B subunit alpha OS=Homo sapiens OX=9606 GN=EIF2B1 PE=1 SV=1 5.66 3702.6 - 1.18E+06 - - - 1.7759 - 1.255 0.065 - 126.3 1 2 0 0.0015 7 0 0 0 6.73E+06 6.77E+06 - - - 0.2403 0.9973 221125_WJC_METTL3_EV_vs_WT_F01.19815.19815.2 2.75 12-Aug R.IIWELIK[136.11].E "sp|O75874|IDHC_HUMAN,tr|C9JLU6|C9JLU6_HUMAN,tr|C9J4N6|C9J4N6_HUMAN,tr|C9JJE5|C9JJE5_HUMAN" 4 921.5779 2.79 7324 19815 2 921.578102 461.7962 Isocitrate dehydrogenase [NADP] cytoplasmic OS=Homo sapiens OX=9606 GN=IDH1 PE=1 SV=2 6 3702.7 - 1.06E+06 - - - 0.23 - 1.545 0.157 - 159.6 1 2 0 0.0002 7 0 0 0 1.45E+07 5.22E+06 - - - 1.5789 0.9997 221125_WJC_METTL3_EV_vs_WT_F01.19816.19816.2 2.13E-06 14/20 K.TVLELQYVLDK[136.11].L "sp|Q14444|CAPR1_HUMAN,tr|G3V153|G3V153_HUMAN,tr|E9PLA9|E9PLA9_HUMAN" 3 1327.7479 0.92 7325 19816 2 1327.751326 664.8812 Caprin-1 OS=Homo sapiens OX=9606 GN=CAPRIN1 PE=1 SV=2 4.37 3702.9 - 981353 - - - 2.6037 - 2.566 0.534 - 492.2 1 2 0 0.0035 11 0 0 0 1.05E+08 1.14E+08 - - - 5.5333 0.9944 221125_WJC_METTL3_EV_vs_WT_F01.19817.19817.2 0.899 12-Sep R.TLLEFLK.R "sp|Q14232|EI2BA_HUMAN,tr|F5H0D0|F5H0D0_HUMAN,tr|H0YGG4|H0YGG4_HUMAN" 3 862.5164 1.01 7326 19817 2 862.517637 432.2655 Translation initiation factor eIF-2B subunit alpha OS=Homo sapiens OX=9606 GN=EIF2B1 PE=1 SV=1 5.66 3703 - 948589 - - - 1.4284 - 1.537 0.132 - 251.8 1 2 0 0.0012 7 0 0 0 6.63E+06 6.57E+06 - - - 1.3775 0.9999 221125_WJC_METTL3_EV_vs_WT_F01.19818.19818.3 1.14E-05 15/48 R.VETPVLPPVLVPR.H "sp|O15198|SMAD9_HUMAN,sp|Q15796|SMAD2_HUMAN,sp|P84022|SMAD3_HUMAN,tr|H3BVD1|H3BVD1_HUMAN,tr|H0YMP2|H0YMP2_HUMAN,tr|K7EJX0|K7EJX0_HUMAN,tr|H3BP09|H3BP09_HUMAN,tr|B7Z5N5|B7Z5N5_HUMAN,tr|H0YL71|H0YL71_HUMAN" 9 1414.8548 1.37 7327 19818 3 1414.857973 472.6255 Mothers against decapentaplegic homolog 9 OS=Homo sapiens OX=9606 GN=SMAD9 PE=1 SV=1 5.97 3703.1 - 864688 - - - 2.2518 - 2.742 0.461 - 317.6 1 2 0 0.0032 13 0 0 0 7.47E+06 5.46E+06 - - - 6.4137 0.9997 221125_WJC_METTL3_EV_vs_WT_F01.19820.19820.2 8.34E-05 20-Nov R.YLLLLAAGDPR[166.11].E "sp|Q5VYK3|ECM29_HUMAN,tr|J3KN16|J3KN16_HUMAN,tr|A0A804HJA4|A0A804HJA4_HUMAN,tr|R4GMY1|R4GMY1_HUMAN" 4 1210.6949 2.28 7329 19820 2 1210.696095 606.3547 Proteasome adapter and scaffold protein ECM29 OS=Homo sapiens OX=9606 GN=ECPAS PE=1 SV=2 5.84 3703.3 - 486393 - - - 0.9631 - 2.202 0.372 - 338.6 1 2 0 0.0012 11 0 0 0 9.05E+06 3.96E+06 - - - 3.9236 0.9991 221125_WJC_METTL3_EV_vs_WT_F01.19823.19823.3 0.00164 Nov-52 R.GAAGALLVYDITSR.E "sp|P61018|RAB4B_HUMAN,sp|P20338|RAB4A_HUMAN" 2 1405.7565 1.66 7332 19823 3 1405.756495 469.5928 Ras-related protein Rab-4B OS=Homo sapiens OX=9606 GN=RAB4B PE=1 SV=1 5.84 3703.7 - 244731 - - - -0.0242 - 1.846 0.287 - 168.3 1 2 0 0 14 0 0 0 3.33E+06 2.00E+06 - - - 3.3689 0.9996 221125_WJC_METTL3_EV_vs_WT_F01.19827.19827.2 0.00274 20-Nov R.TLVLLDNLNVR[166.11].E "sp|P39656|OST48_HUMAN,tr|U3KQ84|U3KQ84_HUMAN,tr|A0A0C4DGS1|A0A0C4DGS1_HUMAN" 3 1278.7535 1.41 7334 19827 2 1278.755219 640.384 Dolichyl-diphosphooligosaccharide--protein glycosyltransferase 48 kDa subunit OS=Homo sapiens OX=9606 GN=DDOST PE=1 SV=4 5.5 3704.2 - 8.90E+06 - - - 1.3396 - 2.393 0.335 - 438.8 1 2 0 0.0017 11 0 0 0 8.45E+07 6.01E+07 - - - 3.8752 0.9998 221125_WJC_METTL3_EV_vs_WT_F01.19828.19828.2 0.00428 18-Dec R.DAVLLVFANK.Q "sp|P84077|ARF1_HUMAN,sp|P61204|ARF3_HUMAN,sp|P84085|ARF5_HUMAN,tr|F5H423|F5H423_HUMAN,tr|C9J1Z8|C9J1Z8_HUMAN" 5 1088.623 1.17 7335 19828 2 1088.623661 545.3188 ADP-ribosylation factor 1 OS=Homo sapiens OX=9606 GN=ARF1 PE=1 SV=2 5.84 3704.2 - 8.23E+06 - - - 0.6109 - 2.467 0.392 - 736.3 1 2 0 0.0007 10 0 0 0 2.78E+08 2.36E+08 - - - 4.4567 0.9999 221125_WJC_METTL3_EV_vs_WT_F01.19829.19829.2 0.000319 20-Dec K.TVLELQYVLDK.L "sp|Q14444|CAPR1_HUMAN,tr|G3V153|G3V153_HUMAN,tr|E9PLA9|E9PLA9_HUMAN" 3 1319.7337 0.92 7336 19829 2 1319.734262 660.8741 Caprin-1 OS=Homo sapiens OX=9606 GN=CAPRIN1 PE=1 SV=2 4.37 3704.3 - 4.05E+06 - - - 0.4493 - 2.398 0.468 - 354.5 1 2 0 0.0006 11 0 0 0 1.05E+08 1.14E+08 - - - 4.8636 0.9998 221125_WJC_METTL3_EV_vs_WT_F01.19831.19831.2 1.92E-06 18-Oct R.VFYYLVQDLK[136.11].C "sp|Q96A72|MGN2_HUMAN,sp|P61326|MGN_HUMAN,tr|F5H6P7|F5H6P7_HUMAN" 3 1294.7053 1.64 7338 19831 2 1294.706957 648.3599 Protein mago nashi homolog 2 OS=Homo sapiens OX=9606 GN=MAGOHB PE=1 SV=1 5.8 3704.4 - 1.66E+06 - - - 1.2991 - 2.242 0.529 - 401 1 2 0 0.0017 10 0 0 0 4.58E+07 2.80E+07 - - - 5.2013 0.9608 221125_WJC_METTL3_EV_vs_WT_F01.19832.19832.2 0.0915 18-Jul K.DLTSVNILLK.K "sp|O15020|SPTN2_HUMAN,sp|Q01082|SPTB2_HUMAN,tr|A0A087WUZ3|A0A087WUZ3_HUMAN" 3 1114.6598 1.8 7339 19832 2 1114.663453 558.3372 "Spectrin beta chain, non-erythrocytic 2 OS=Homo sapiens OX=9606 GN=SPTBN2 PE=1 SV=3" 5.84 3704.5 - 875637 - - - 3.2997 - 1.292 0.149 - 109.2 1 2 0 0.0037 10 0 0 0 7.89E+06 4.39E+06 - - - 0.8555 0.9997 221125_WJC_METTL3_EV_vs_WT_F01.19833.19833.3 0.0037 Oct-40 R.TLVLLDNLNVR[166.11].E "sp|P39656|OST48_HUMAN,tr|U3KQ84|U3KQ84_HUMAN,tr|A0A0C4DGS1|A0A0C4DGS1_HUMAN" 3 1278.7535 1.63 7340 19833 3 1278.753819 427.2584 Dolichyl-diphosphooligosaccharide--protein glycosyltransferase 48 kDa subunit OS=Homo sapiens OX=9606 GN=DDOST PE=1 SV=4 5.5 3704.7 - 574832 - - - 0.2448 - 2.073 0.319 - 207.2 1 2 0 0.0003 11 0 0 0 4.55E+06 2.79E+06 - - - 4.1674 0.9996 221125_WJC_METTL3_EV_vs_WT_F01.19835.19835.2 0.00687 20-Oct R.YVDQVLQLVYK[136.11].D sp|P11717|MPRI_HUMAN 1 1374.7639 2.58 7342 19835 2 1374.766028 688.3892 Cation-independent mannose-6-phosphate receptor OS=Homo sapiens OX=9606 GN=IGF2R PE=1 SV=3 5.83 3704.9 - 522996 - - - 1.5821 - 2.224 0.389 - 253.4 1 2 0 0.0022 11 0 0 0 8.11E+06 3.15E+06 - - - 4.0758 0.9877 221125_WJC_METTL3_EV_vs_WT_F01.19839.19839.2 0.0281 22-Aug R.GLSSLLYGSIPK.A sp|P53007|TXTP_HUMAN 1 1233.6969 0.44 7346 19839 2 1233.693491 617.8557 "Tricarboxylate transport protein, mitochondrial OS=Homo sapiens OX=9606 GN=SLC25A1 PE=1 SV=2" 8.59 3705.4 - 901036 - - - -2.7543 - 1.186 0.259 - 92 1 2 0 -0.0034 12 0 0 0 1.71E+06 3.86E+06 - - - 1.4017 0.9998 221125_WJC_METTL3_EV_vs_WT_F01.19841.19841.2 0.0124 26-Dec R.LEALLEAADPEVLR.R tr|D6RHC4|D6RHC4_HUMAN 1 1537.8352 1.85 7348 19841 2 1537.835282 769.9249 Ankyrin repeat and KH domain-containing protein 1 (Fragment) OS=Homo sapiens OX=9606 GN=ANKHD1 PE=1 SV=1 4 3705.7 - 196230 - - - 0.0702 - 2.423 0.399 - 415.6 1 2 0 0.0001 14 0 0 0 6.47E+06 3.51E+06 - - - 4.2089 0.9999 221125_WJC_METTL3_EV_vs_WT_F01.19845.19845.2 1.10E-06 18-Nov K.LMDVGLIAIR[166.11].- sp|P31948|STIP1_HUMAN 1 1109.6506 3.88 7350 19845 2 1109.651338 555.8326 Stress-induced-phosphoprotein 1 OS=Homo sapiens OX=9606 GN=STIP1 PE=1 SV=1 5.84 3706.2 - 5.86E+06 - - - 0.6461 - 2.177 0.503 - 413.3 1 2 0 0.0007 10 0 0 0 1.31E+08 3.38E+07 - - - 4.9274 0.8897 221125_WJC_METTL3_EV_vs_WT_F01.19846.19846.2 0.964 18-May K.VGDYGIGFSR[166.11].Y sp|Q8IWU2|LMTK2_HUMAN 1 1079.5275 0.01 7351 19846 2 1079.525348 540.771 Serine\threonine-protein kinase LMTK2 OS=Homo sapiens OX=9606 GN=LMTK2 PE=1 SV=2 5.81 3706.3 - 5.34E+06 - - - -2.0203 - 0.904 0.121 - 54 2 2 0 -0.0022 10 0 0 0 5.54E+05 7.72E+07 - - - -0.4822 0.9992 221125_WJC_METTL3_EV_vs_WT_F01.19851.19851.2 0.00401 22-Dec R.ALLANALTSALR.L "sp|P57088|TMM33_HUMAN,tr|D6RAA6|D6RAA6_HUMAN" 2 1212.719 0.89 7356 19851 2 1212.722848 607.3668 Transmembrane protein 33 OS=Homo sapiens OX=9606 GN=TMEM33 PE=1 SV=2 9.79 3706.7 - 971364 - - - 3.1557 - 2.437 0.411 - 517.1 1 2 0 0.0038 12 0 0 0 6.33E+06 7.12E+06 - - - 4.4192 0.9997 221125_WJC_METTL3_EV_vs_WT_F01.19853.19853.2 0.000734 18-Aug K.DLTSVNILLK[136.11].K "sp|O15020|SPTN2_HUMAN,sp|Q01082|SPTB2_HUMAN,tr|A0A087WUZ3|A0A087WUZ3_HUMAN" 3 1122.674 1.8 7358 19853 2 1122.674116 562.3443 "Spectrin beta chain, non-erythrocytic 2 OS=Homo sapiens OX=9606 GN=SPTBN2 PE=1 SV=3" 5.84 3706.8 - 867179 - - - 0.1256 - 1.764 0.378 - 149.2 1 2 0 0.0001 10 0 0 0 7.89E+06 4.39E+06 - - - 3.4172 0.9986 221125_WJC_METTL3_EV_vs_WT_F01.19854.19854.2 0.0813 16-Sep R.LELPADLLR.Q "sp|Q96NU1|SAM11_HUMAN,tr|A0A087WYW1|A0A087WYW1_HUMAN,tr|A0A087WX24|A0A087WX24_HUMAN,tr|A0A087X1J5|A0A087X1J5_HUMAN,tr|A0A087X223|A0A087X223_HUMAN,tr|H7BY14|H7BY14_HUMAN,tr|A0A087WXB3|A0A087WXB3_HUMAN,tr|H7C3J6|H7C3J6_HUMAN,tr|A0A087WYU3|A0A087WYU3_HUMAN,tr|A0A087WU74|A0A087WU74_HUMAN" 10 1038.6073 1.24 7359 19854 2 1038.609467 520.3109 Sterile alpha motif domain-containing protein 11 OS=Homo sapiens OX=9606 GN=SAMD11 PE=1 SV=3 4.37 3706.9 - 867081 - - - 2.0422 - 1.906 0.261 - 280.2 1 2 0 0.0021 9 0 0 0 1.17E+07 9.51E+06 - - - 2.8341 0.9999 221125_WJC_METTL3_EV_vs_WT_F01.19855.19855.3 0.000263 Nov-40 R.TLVLLDNLNVR.E "sp|P39656|OST48_HUMAN,tr|U3KQ84|U3KQ84_HUMAN,tr|A0A0C4DGS1|A0A0C4DGS1_HUMAN" 3 1268.7452 1.61 7360 19855 3 1268.745139 423.9224 Dolichyl-diphosphooligosaccharide--protein glycosyltransferase 48 kDa subunit OS=Homo sapiens OX=9606 GN=DDOST PE=1 SV=4 5.5 3707.1 - 711425 - - - -0.0765 - 2.266 0.38 - 268.7 1 2 0 -0.0001 11 0 0 0 4.55E+06 2.82E+06 - - - 5.1004 0.9979 221125_WJC_METTL3_EV_vs_WT_F01.19856.19856.2 0.425 14-Jul R.LLLTPWVK.F sp|Q14152|EIF3A_HUMAN 1 968.6059 1.17 7361 19856 2 968.605984 485.3102 Eukaryotic translation initiation factor 3 subunit A OS=Homo sapiens OX=9606 GN=EIF3A PE=1 SV=1 8.75 3707.2 - 617031 - - - 0.0981 - 1.413 0.227 - 124.8 1 2 0 0.0001 8 0 0 0 5.75E+06 4.93E+06 - - - 1.7603 1 221125_WJC_METTL3_EV_vs_WT_F01.19857.19857.2 1.85E-08 14/22 K.LYDNLLEQNLIR[166.11].V sp|O00231|PSD11_HUMAN 1 1512.8176 0.69 7362 19857 2 1512.816972 757.4161 26S proteasome non-ATPase regulatory subunit 11 OS=Homo sapiens OX=9606 GN=PSMD11 PE=1 SV=3 4.37 3707.3 - 552603 - - - -0.3907 - 3.039 0.616 - 842.5 1 2 0 -0.0006 12 0 0 0 1.49E+07 2.16E+07 - - - 6.5152 0.9996 221125_WJC_METTL3_EV_vs_WT_F01.19858.19858.2 0.00123 20-Oct R.YLLLLAAGDPR.E "sp|Q5VYK3|ECM29_HUMAN,tr|J3KN16|J3KN16_HUMAN,tr|A0A804HJA4|A0A804HJA4_HUMAN,tr|R4GMY1|R4GMY1_HUMAN" 4 1200.6867 1.7 7363 19858 2 1200.685086 601.3506 Proteasome adapter and scaffold protein ECM29 OS=Homo sapiens OX=9606 GN=ECPAS PE=1 SV=2 5.84 3707.4 - 521307 - - - -1.3101 - 2.106 0.33 - 269 1 2 0 -0.0016 11 0 0 0 6.75E+06 3.96E+06 - - - 3.4927 0.9992 221125_WJC_METTL3_EV_vs_WT_F01.19860.19860.2 0.008 20-Sep R.YVDQVLQLVYK.D sp|P11717|MPRI_HUMAN 1 1366.7497 1.19 7365 19860 2 1366.747638 684.3821 Cation-independent mannose-6-phosphate receptor OS=Homo sapiens OX=9606 GN=IGF2R PE=1 SV=3 5.83 3707.7 - 504056 - - - -1.4743 - 1.552 0.38 - 193.2 1 2 0 -0.002 11 0 0 0 3.57E+06 3.00E+06 - - - 3.0361 1 221125_WJC_METTL3_EV_vs_WT_F01.19862.19862.2 1.06E-08 15/22 K.LYDNLLEQNLIR.V sp|O00231|PSD11_HUMAN 1 1502.8093 0.7 7367 19862 2 1502.8107 752.4119 26S proteasome non-ATPase regulatory subunit 11 OS=Homo sapiens OX=9606 GN=PSMD11 PE=1 SV=3 4.37 3707.9 - 459421 - - - 0.9362 - 3.103 0.597 - 1000.1 1 2 0 0.0014 12 0 0 0 1.50E+07 2.16E+07 - - - 6.4295 0.98 221125_WJC_METTL3_EV_vs_WT_F01.19869.19869.2 1.46 14-Sep R.LLLTPWVK[136.11].F sp|Q14152|EIF3A_HUMAN 1 976.6201 1.1 7373 19869 2 976.620261 489.3173 Eukaryotic translation initiation factor 3 subunit A OS=Homo sapiens OX=9606 GN=EIF3A PE=1 SV=1 8.75 3708.7 - 1.12E+06 - - - 0.1761 - 1.126 0.104 - 183.9 1 2 0 0.0002 8 0 0 0 5.42E+06 4.93E+06 - - - 0.167 0.999 221125_WJC_METTL3_EV_vs_WT_F01.19870.19870.2 0.00691 20-Nov K.TYLQALPYFDR[166.11].L "sp|O75306|NDUS2_HUMAN,tr|A0A7I2V4X8|A0A7I2V4X8_HUMAN,tr|A0A7I2V4G5|A0A7I2V4G5_HUMAN,tr|A0A7I2V5D5|A0A7I2V5D5_HUMAN,tr|A0A7I2YQG7|A0A7I2YQG7_HUMAN,tr|A0A7I2V596|A0A7I2V596_HUMAN,tr|A0A7I2V5G4|A0A7I2V5G4_HUMAN,tr|A0A7I2V410|A0A7I2V410_HUMAN,tr|A0A7I2V630|A0A7I2V630_HUMAN,tr|A0A7I2V2B9|A0A7I2V2B9_HUMAN,tr|A0A7I2YQD8|A0A7I2YQD8_HUMAN,tr|A0A7I2V517|A0A7I2V517_HUMAN,tr|A0A7I2V3J6|A0A7I2V3J6_HUMAN,tr|A0A7I2V5E2|A0A7I2V5E2_HUMAN,tr|A0A7I2V4W5|A0A7I2V4W5_HUMAN" 15 1395.7062 1 7374 19870 2 1395.709321 698.8604 "NADH dehydrogenase [ubiquinone] iron-sulfur protein 2, mitochondrial OS=Homo sapiens OX=9606 GN=NDUFS2 PE=1 SV=2" 5.5 3708.9 - 782109 - - - 2.2204 - 1.749 0.371 - 301.8 1 2 0 0.0031 11 0 0 0 4.67E+06 4.68E+06 - - - 3.2926 0.9913 221125_WJC_METTL3_EV_vs_WT_F01.19875.19875.2 0.0118 16-Aug R.FPVDIFYTK[136.11].A "sp|O60231|DHX16_HUMAN,tr|A0A140T947|A0A140T947_HUMAN,tr|A0A140T9T4|A0A140T9T4_HUMAN,tr|Q5SQH5|Q5SQH5_HUMAN,tr|A0A140T8Y5|A0A140T8Y5_HUMAN" 5 1136.5997 1.34 7379 19875 2 1136.594892 569.3072 Pre-mRNA-splicing factor ATP-dependent RNA helicase DHX16 OS=Homo sapiens OX=9606 GN=DHX16 PE=1 SV=2 5.83 3709.5 - 317416 - - - -4.2724 - 1.558 0.309 - 146.3 1 2 0 -0.0049 9 0 0 0 5.63E+06 4.20E+06 - - - 2.6045 0.9999 221125_WJC_METTL3_EV_vs_WT_F01.19881.19881.2 2.12E-05 18-Nov R.DAVLLVFANK[136.11].Q "sp|P84077|ARF1_HUMAN,sp|P61204|ARF3_HUMAN,sp|P84085|ARF5_HUMAN,tr|F5H423|F5H423_HUMAN,tr|C9J1Z8|C9J1Z8_HUMAN" 5 1096.6372 1.17 7383 19881 2 1096.637052 549.3259 ADP-ribosylation factor 1 OS=Homo sapiens OX=9606 GN=ARF1 PE=1 SV=2 5.84 3710.3 - 3.22E+07 - - - -0.1313 - 2.339 0.533 - 618.6 1 2 0 -0.0001 10 0 0 0 2.78E+08 2.36E+08 - - - 5.3495 0.9729 221125_WJC_METTL3_EV_vs_WT_F01.19883.19883.2 0.000153 20-Jul K.FEQLVSIGSSY.N sp|Q9NXV2|KCTD5_HUMAN 1 1228.5976 - 7385 19883 2 1228.598644 615.3061 BTB\POZ domain-containing protein KCTD5 OS=Homo sapiens OX=9606 GN=KCTD5 PE=1 SV=1 4 3710.4 - 2.15E+06 - - - 0.875 - 1.492 0.435 - 152.3 1 1 0 0.0011 11 0 0 0 - - - - - 3.336 0.9016 221125_WJC_METTL3_EV_vs_WT_F01.19884.19884.2 1.69 12-Mar K.WSDMEDR[166.11].H "sp|Q8N0V5|GNT2A_HUMAN,tr|B7ZBL3|B7ZBL3_HUMAN" 2 947.3683 0.01 7386 19884 2 947.369205 474.6914 "N-acetyllactosaminide beta-1,6-N-acetylglucosaminyl-transferase OS=Homo sapiens OX=9606 GN=GCNT2 PE=1 SV=1" 4.03 3710.5 - 1.03E+06 - - - 1.007 - 0.618 0.24 - 32.3 1 2 0 0.001 7 0 0 0 3.96E+04 5.14E+06 - - - -0.7116 0.9999 221125_WJC_METTL3_EV_vs_WT_F01.19885.19885.2 8.11E-06 17/28 R.LPLPSPALEYTLGSR.L sp|Q8IU81|I2BP1_HUMAN 1 1612.8825 1.34 7387 19885 2 1612.882379 807.4485 Interferon regulatory factor 2-binding protein 1 OS=Homo sapiens OX=9606 GN=IRF2BP1 PE=1 SV=1 6 3710.7 - 1.02E+06 - - - -0.049 - 2.754 0.486 - 866.2 1 2 0 -0.0001 15 0 0 0 4.58E+07 3.41E+07 - - - 5.1212 0.9839 221125_WJC_METTL3_EV_vs_WT_F01.19887.19887.3 0.145 Jul-44 K.LYDNLLEQNLIR[166.11].V sp|O00231|PSD11_HUMAN 1 1512.8176 0.65 7389 19887 3 1512.817419 505.2798 26S proteasome non-ATPase regulatory subunit 11 OS=Homo sapiens OX=9606 GN=PSMD11 PE=1 SV=3 4.37 3710.8 - 965960 - - - -0.0952 - 1.701 0.155 - 85.9 3 2 0 -0.0001 12 0 0 0 2.86E+06 4.44E+06 - - - 1.5197 0.9788 221125_WJC_METTL3_EV_vs_WT_F01.19889.19889.2 7.01 18-Jul K.LGLFPSNFVK[136.11].E sp|Q9Y5K6|CD2AP_HUMAN 1 1128.6423 0.16 7391 19889 2 1128.642062 565.3284 CD2-associated protein OS=Homo sapiens OX=9606 GN=CD2AP PE=1 SV=1 8.75 3711 - 677472 - - - -0.194 - 1.261 0.058 - 79.5 1 2 0 -0.0002 10 0 0 0 7.22E+05 4.45E+06 - - - 0.1166 0.9998 221125_WJC_METTL3_EV_vs_WT_F01.19891.19891.2 0.00913 16-Oct R.IQEFIELIR.Q "sp|Q7L5Y9|MAEA_HUMAN,tr|B4DVN3|B4DVN3_HUMAN,tr|B4DQT1|B4DQT1_HUMAN,tr|E7ESC7|E7ESC7_HUMAN,tr|D6RE80|D6RE80_HUMAN" 5 1159.6601 0.1 7393 19891 2 1159.660259 580.8373 E3 ubiquitin-protein transferase MAEA OS=Homo sapiens OX=9606 GN=MAEA PE=1 SV=1 4.53 3711.3 - 631990 - - - 0.1285 - 2.145 0.392 - 316.4 1 2 0 0.0001 9 0 0 0 3.30E+06 3.37E+07 - - - 4.1441 0.995 221125_WJC_METTL3_EV_vs_WT_F01.19892.19892.2 1.81 13/22 R.ALLANALTSALR[166.11].L "sp|P57088|TMM33_HUMAN,tr|D6RAA6|D6RAA6_HUMAN" 2 1222.7273 0.89 7394 19892 2 1222.727954 612.3709 Transmembrane protein 33 OS=Homo sapiens OX=9606 GN=TMEM33 PE=1 SV=2 9.79 3711.4 - 609477 - - - 0.5422 - 1.661 0.107 - 397.3 1 2 0 0.0007 12 0 0 0 6.33E+06 7.12E+06 - - - 1.1662 0.9999 221125_WJC_METTL3_EV_vs_WT_F01.19893.19893.2 0.000407 15/28 R.LPLPSPALEYTLGSR[166.11].L sp|Q8IU81|I2BP1_HUMAN 1 1622.8907 1.34 7395 19893 2 1622.890087 812.4526 Interferon regulatory factor 2-binding protein 1 OS=Homo sapiens OX=9606 GN=IRF2BP1 PE=1 SV=1 6 3711.5 - 581047 - - - -0.395 - 2.524 0.465 - 592.1 1 2 0 -0.0006 15 0 0 0 4.58E+07 3.41E+07 - - - 4.7515 0.8328 221125_WJC_METTL3_EV_vs_WT_F01.19897.19897.2 0.0698 18-Jul R.IAHIPLYFVN.A "sp|Q9NRG9|AAAS_HUMAN,tr|F8VZ44|F8VZ44_HUMAN" 2 1185.6546 - 7399 19897 2 1185.65251 593.8346 Aladin OS=Homo sapiens OX=9606 GN=AAAS PE=1 SV=1 6.74 3712.1 - 458457 - - - -1.788 - 1.486 0.235 - 126.7 1 1 0 -0.0021 10 0 0 0 - - - - - 1.8816 0.9999 221125_WJC_METTL3_EV_vs_WT_F01.19898.19898.2 0.000914 18-Oct R.FSDFLGLYEK.L sp|Q13596|SNX1_HUMAN 1 1217.5968 1.46 7400 19898 2 1217.597575 609.8057 Sorting nexin-1 OS=Homo sapiens OX=9606 GN=SNX1 PE=1 SV=3 4.37 3712.2 - 443356 - - - 0.6028 - 2.201 0.532 - 227.9 1 2 0 0.0007 10 0 0 0 4.76E+06 3.26E+06 - - - 5.1722 0.9999 221125_WJC_METTL3_EV_vs_WT_F01.19899.19899.2 3.02E-08 28-Nov R.LASEYLTPEEMVTFK.K sp|O43290|SNUT1_HUMAN 1 1756.8593 4.33 7401 19899 2 1756.857355 879.4369 U4\U6.U5 tri-snRNP-associated protein 1 OS=Homo sapiens OX=9606 GN=SART1 PE=1 SV=1 4.25 3712.3 - 371287 - - - -1.1293 - 2.498 0.548 - 323.1 1 2 0 -0.002 15 0 0 0 2.07E+06 4.77E+05 - - - 5.3387 0.9996 221125_WJC_METTL3_EV_vs_WT_F01.19903.19903.2 1.85E-07 22-Nov K.IYYPDFIVPDPK.K sp|P49916|DNLI3_HUMAN 1 1465.7493 3.2 7404 19903 2 1465.745265 733.8819 DNA ligase 3 OS=Homo sapiens OX=9606 GN=LIG3 PE=1 SV=2 4.21 3712.8 - 228355 - - - -2.7658 - 2.077 0.547 - 402.4 1 2 0 -0.0041 12 0 0 0 1.30E+06 4.06E+05 - - - 5.0031 0.9823 221125_WJC_METTL3_EV_vs_WT_F01.19904.19904.2 0.363 20-Dec K.NAAIAVLEELK.K "sp|O95793|STAU1_HUMAN,tr|Q5JW30|Q5JW30_HUMAN,tr|Q5JW28|Q5JW28_HUMAN" 3 1169.6656 1.96 7405 19904 2 1169.671432 585.8401 Double-stranded RNA-binding protein Staufen homolog 1 OS=Homo sapiens OX=9606 GN=STAU1 PE=1 SV=2 4.53 3712.8 - 2.96E+06 - - - 4.9954 - 1.974 0.213 - 499.7 1 2 0 0.0058 11 0 0 0 3.93E+07 2.01E+07 - - - 2.4521 0.9949 221125_WJC_METTL3_EV_vs_WT_F01.19906.19906.2 0.00883 18-Nov R.QEVVELLLAR[166.11].G "sp|O75179|ANR17_HUMAN,tr|H0YM23|H0YM23_HUMAN,tr|H0YLQ3|H0YLQ3_HUMAN" 3 1178.6898 1.02 7407 19906 2 1178.687015 590.3522 Ankyrin repeat domain-containing protein 17 OS=Homo sapiens OX=9606 GN=ANKRD17 PE=1 SV=3 4.53 3713 - 1.90E+06 - - - -2.3993 - 2.147 0.096 - 574 1 2 0 -0.0028 10 0 0 0 1.59E+07 1.57E+07 - - - 1.8819 0.9991 221125_WJC_METTL3_EV_vs_WT_F01.19908.19908.2 0.0142 14-Sep K.EILIPVFK[136.11].N sp|P53396|ACLY_HUMAN 1 965.6041 0.62 7409 19908 2 965.605227 483.8093 ATP-citrate synthase OS=Homo sapiens OX=9606 GN=ACLY PE=1 SV=3 6.1 3713.1 - 1.41E+06 - - - 1.162 - 1.675 0.301 - 254.8 1 2 0 0.0011 8 0 0 0 1.02E+07 1.64E+07 - - - 2.8195 0.9987 221125_WJC_METTL3_EV_vs_WT_F01.19909.19909.2 0.0269 22-Sep K.ALFSLAPEVEVR[166.11].V "sp|Q8N3Z3|GTPB8_HUMAN,tr|C9J8V5|C9J8V5_HUMAN,tr|F8WBY6|F8WBY6_HUMAN" 3 1339.7375 0.41 7410 19909 2 1339.739133 670.876 GTP-binding protein 8 OS=Homo sapiens OX=9606 GN=GTPBP8 PE=1 SV=1 4.53 3713.2 - 1.25E+06 - - - 1.2025 - 1.636 0.286 - 163.1 1 2 0 0.0016 12 0 0 0 4.65E+06 1.13E+07 - - - 2.4481 0.999 221125_WJC_METTL3_EV_vs_WT_F01.19911.19911.2 0.0636 14-Sep K.EILIPVFK.N sp|P53396|ACLY_HUMAN 1 957.5899 0.62 7412 19911 2 957.591247 479.8022 ATP-citrate synthase OS=Homo sapiens OX=9606 GN=ACLY PE=1 SV=3 6.1 3713.5 - 908605 - - - 1.4014 - 1.67 0.305 - 249.3 1 2 0 0.0013 8 0 0 0 1.02E+07 1.64E+07 - - - 2.84 0.9999 221125_WJC_METTL3_EV_vs_WT_F01.19913.19913.3 5.05E-06 Dec-64 K.VALVTASTDGIGFAIAR.R "sp|Q6PKH6|DR4L2_HUMAN,sp|Q9BTZ2|DHRS4_HUMAN,tr|F5GWZ1|F5GWZ1_HUMAN,tr|F6TD35|F6TD35_HUMAN,tr|E9PFL3|E9PFL3_HUMAN" 5 1660.9148 1.81 7414 19913 3 1660.918055 554.6456 Dehydrogenase\reductase SDR family member 4-like 2 OS=Homo sapiens OX=9606 GN=DHRS4L2 PE=2 SV=2 5.81 3713.7 - 699345 - - - 1.9471 - 2.405 0.499 - 168.2 1 2 0 0.0032 17 0 0 0 2.48E+06 1.37E+06 - - - 6.3194 0.9282 221125_WJC_METTL3_EV_vs_WT_F01.19914.19914.2 3.28E-06 14/22 Y.VLNPLAPEFIPR.A "sp|P42694|HELZ_HUMAN,tr|J3QS41|J3QS41_HUMAN" 2 1364.7816 3.49 7415 19914 2 1364.787933 683.3981 Probable helicase with zinc finger domain OS=Homo sapiens OX=9606 GN=HELZ PE=1 SV=2 5.97 3713.8 - 693377 - - - 4.6242 - 2.64 0.543 - 707.1 1 1 0 0.0063 12 0 0 0 3.82E+06 1.10E+06 - - - 5.6039 1 221125_WJC_METTL3_EV_vs_WT_F01.19915.19915.2 6.88E-08 17/32 K.VALVTASTDGIGFAIAR[166.11].R "sp|Q6PKH6|DR4L2_HUMAN,sp|Q9BTZ2|DHRS4_HUMAN,tr|F5GWZ1|F5GWZ1_HUMAN,tr|F6TD35|F6TD35_HUMAN,tr|E9PFL3|E9PFL3_HUMAN" 5 1670.9231 1.28 7416 19915 2 1670.924914 836.4688 Dehydrogenase\reductase SDR family member 4-like 2 OS=Homo sapiens OX=9606 GN=DHRS4L2 PE=2 SV=2 5.81 3713.9 - 614766 - - - 1.091 - 3.545 0.499 - 899.7 1 2 0 0.0018 17 0 0 0 3.45E+06 2.69E+06 - - - 5.8374 0.8398 221125_WJC_METTL3_EV_vs_WT_F01.19917.19917.2 0.00064 24-Jul R.MLDNDSILVDAIR.K "sp|O75175|CNOT3_HUMAN,tr|B7Z6J7|B7Z6J7_HUMAN,tr|A0A2H2FJL5|A0A2H2FJL5_HUMAN,tr|H7C3F5|H7C3F5_HUMAN,tr|A0A2R8Y6N5|A0A2R8Y6N5_HUMAN,tr|A0A0G2JNJ7|A0A0G2JNJ7_HUMAN,tr|H7C148|H7C148_HUMAN" 7 1473.7497 5.4 7418 19917 2 1473.756023 737.8821 CCR4-NOT transcription complex subunit 3 OS=Homo sapiens OX=9606 GN=CNOT3 PE=1 SV=1 3.93 3714.2 - 406480 - - - 4.2707 - 1.405 0.071 - 72.7 2 2 0 0.0063 13 0 0 0 9.43E+06 1.75E+06 - - - 0.3017 0.9459 221125_WJC_METTL3_EV_vs_WT_F01.19923.19923.2 0.0517 20-Sep K.LFPGFEIETVK[136.11].N "sp|P08243|ASNS_HUMAN,tr|F8WEJ5|F8WEJ5_HUMAN" 2 1286.7002 0.01 7423 19923 2 1286.695835 644.3574 Asparagine synthetase [glutamine-hydrolyzing] OS=Homo sapiens OX=9606 GN=ASNS PE=1 SV=4 4.53 3714.9 - 796562 - - - -3.3846 - 1.496 0.089 - 187.3 2 2 0 -0.0044 11 0 0 0 3.63E+05 4.73E+07 - - - 0.6522 0.9999 221125_WJC_METTL3_EV_vs_WT_F01.19928.19928.2 0.000497 20/30 R.ALIAGGGAPEIELALR[166.11].L sp|P50991|TCPD_HUMAN 1 1559.8911 0.36 7428 19928 2 1559.893067 780.9528 T-complex protein 1 subunit delta OS=Homo sapiens OX=9606 GN=CCT4 PE=1 SV=4 4.53 3715.3 - 1.26E+06 - - - 1.2853 - 3.015 0.504 - 1674.1 1 2 0 0.002 16 0 0 0 7.31E+07 2.01E+08 - - - 5.4762 0.9994 221125_WJC_METTL3_EV_vs_WT_F01.19929.19929.2 0.0353 14-Oct K.QDILTIFK.R "sp|Q9NP61|ARFG3_HUMAN,tr|B0QYV8|B0QYV8_HUMAN" 2 976.5593 1.24 7429 19929 2 976.561105 489.2869 ADP-ribosylation factor GTPase-activating protein 3 OS=Homo sapiens OX=9606 GN=ARFGAP3 PE=1 SV=1 5.84 3715.4 - 1.16E+06 - - - 1.8145 - 1.996 0.342 - 309.1 1 2 0 0.0018 8 0 0 0 1.56E+07 1.26E+07 - - - 3.6509 0.9987 221125_WJC_METTL3_EV_vs_WT_F01.19933.19933.2 0.104 12-Jul R.DVFLMLK[136.11].K "sp|O00139|KIF2A_HUMAN,tr|D6R9M0|D6R9M0_HUMAN,tr|A0A6Q8PFA6|A0A6Q8PFA6_HUMAN,tr|A0A6Q8PGG1|A0A6Q8PGG1_HUMAN,tr|A0A6Q8PGH7|A0A6Q8PGH7_HUMAN,tr|A0A6Q8PG37|A0A6Q8PG37_HUMAN,tr|A0A6Q8PH57|A0A6Q8PH57_HUMAN" 7 872.4921 1.19 7433 19933 2 872.492978 437.2533 Kinesin-like protein KIF2A OS=Homo sapiens OX=9606 GN=KIF2A PE=1 SV=3 5.84 3715.9 - 580742 - - - 0.9937 - 1.356 0.319 - 167.3 1 2 0 0.0009 7 0 0 0 3.14E+06 2.64E+06 - - - 2.3618 0.9915 221125_WJC_METTL3_EV_vs_WT_F01.19934.19934.2 0.036 12-Jul K.YLFTLIR.A sp|P57740|NU107_HUMAN 1 924.5433 0.64 7434 19934 2 924.545304 463.2789 Nuclear pore complex protein Nup107 OS=Homo sapiens OX=9606 GN=NUP107 PE=1 SV=1 8.75 3716 - 574619 - - - 2.1795 - 1.395 0.178 - 167.4 1 2 0 0.002 7 0 0 0 1.64E+06 2.58E+06 - - - 1.4099 0.9987 221125_WJC_METTL3_EV_vs_WT_F01.19935.19935.2 0.0168 12-Jul R.DVFLMLK.K "sp|O00139|KIF2A_HUMAN,tr|D6R9M0|D6R9M0_HUMAN,tr|A0A6Q8PFA6|A0A6Q8PFA6_HUMAN,tr|A0A6Q8PGG1|A0A6Q8PGG1_HUMAN,tr|A0A6Q8PGH7|A0A6Q8PGH7_HUMAN,tr|A0A6Q8PG37|A0A6Q8PG37_HUMAN,tr|A0A6Q8PH57|A0A6Q8PH57_HUMAN" 7 864.4779 1.08 7435 19935 2 864.47917 433.2462 Kinesin-like protein KIF2A OS=Homo sapiens OX=9606 GN=KIF2A PE=1 SV=3 5.84 3716.1 - 538192 - - - 1.4564 - 1.389 0.341 - 168.1 1 2 0 0.0013 7 0 0 0 2.85E+06 2.64E+06 - - - 2.6004 0.9999 221125_WJC_METTL3_EV_vs_WT_F01.19936.19936.3 4.22E-05 Nov-40 K.NAAIAVLEELK.K "sp|O95793|STAU1_HUMAN,tr|Q5JW30|Q5JW30_HUMAN,tr|Q5JW28|Q5JW28_HUMAN" 3 1169.6656 2.27 7436 19936 3 1169.664444 390.8958 Double-stranded RNA-binding protein Staufen homolog 1 OS=Homo sapiens OX=9606 GN=STAU1 PE=1 SV=2 4.53 3716.2 - 512762 - - - -0.9789 - 2.101 0.429 - 143.6 1 2 0 -0.0011 11 0 0 0 2.20E+06 9.70E+05 - - - 5.4317 0.9999 221125_WJC_METTL3_EV_vs_WT_F01.19938.19938.2 1.00E-08 13/22 K.C[160.03]PLDPYFIMPDK.C "sp|P33992|MCM5_HUMAN,tr|B1AHB1|B1AHB1_HUMAN,tr|B1AHB2|B1AHB2_HUMAN" 3 1494.6887 0.6 7438 19938 2 1494.688701 748.3516 DNA replication licensing factor MCM5 OS=Homo sapiens OX=9606 GN=MCM5 PE=1 SV=5 4.21 3716.5 - 436779 - - - -0.0054 - 2.533 0.568 - 616.9 1 2 0 0 12 0 0 0 1.85E+06 3.09E+06 - - - 5.6817 0.9921 221125_WJC_METTL3_EV_vs_WT_F01.19939.19939.2 0.147 12-Jul K.YLFTLIR[166.11].A sp|P57740|NU107_HUMAN 1 934.5516 -1 7439 19939 2 934.553475 468.2831 Nuclear pore complex protein Nup107 OS=Homo sapiens OX=9606 GN=NUP107 PE=1 SV=1 8.75 3716.6 - 424840 - - - 2.0502 - 1.389 0.179 - 164.8 1 2 0 0.0019 7 0 0 0 0.00E+00 0.00E+00 - - - 1.4036 0.9969 221125_WJC_METTL3_EV_vs_WT_F01.19940.19940.2 0.134 26-Nov K.IPPPVIMVQNVSFK.Y sp|Q9UG63|ABCF2_HUMAN 1 1567.8796 -1 7440 19940 2 1567.880299 784.9471 ATP-binding cassette sub-family F member 2 OS=Homo sapiens OX=9606 GN=ABCF2 PE=1 SV=2 8.75 3716.8 - 337680 - - - 0.4324 - 1.656 0.161 - 242.9 1 2 0 0.0007 14 0 0 0 0.00E+00 0.00E+00 - - - 1.4957 0.9928 221125_WJC_METTL3_EV_vs_WT_F01.19941.19941.2 0.00212 24-Dec Y.IVGANIETYLLEK[136.11].S "sp|Q7Z406|MYH14_HUMAN,sp|P35580|MYH10_HUMAN,sp|P35749|MYH11_HUMAN,sp|P35579|MYH9_HUMAN,tr|A0A2R8Y4C3|A0A2R8Y4C3_HUMAN,tr|M0QY43|M0QY43_HUMAN,tr|A0A494C024|A0A494C024_HUMAN" 7 1469.8221 0.84 7441 19941 2 1469.823403 735.9183 Myosin-14 OS=Homo sapiens OX=9606 GN=MYH14 PE=1 SV=2 4.53 3716.9 - 322710 - - - 0.8892 - 2.337 0.555 - 326.9 1 1 0 0.0013 13 0 0 0 3.29E+06 3.90E+06 - - - 5.3185 0.9987 221125_WJC_METTL3_EV_vs_WT_F01.19942.19942.2 0.0194 20-Jul K.LLVYEALEYAK.R "sp|Q96DB5|RMD1_HUMAN,tr|H0YB83|H0YB83_HUMAN,tr|E5RH53|E5RH53_HUMAN,tr|H0YB03|H0YB03_HUMAN" 4 1310.7122 0.04 7442 19942 2 1310.712271 656.3634 Regulator of microtubule dynamics protein 1 OS=Homo sapiens OX=9606 GN=RMDN1 PE=1 SV=1 4.53 3717 - 320278 - - - 0.0504 - 1.473 0.281 - 96.3 1 2 0 0.0001 11 0 0 0 1.91E+06 5.16E+07 - - - 2.1642 0.9999 221125_WJC_METTL3_EV_vs_WT_F01.19946.19946.2 5.24E-06 17/30 R.ALIAGGGAPEIELALR.L sp|P50991|TCPD_HUMAN 1 1549.8828 0.36 7445 19946 2 1549.88414 775.9487 T-complex protein 1 subunit delta OS=Homo sapiens OX=9606 GN=CCT4 PE=1 SV=4 4.53 3717.6 - 3.17E+06 - - - 0.8697 - 3.008 0.528 - 838.3 1 2 0 0.0013 16 0 0 0 7.31E+07 2.01E+08 - - - 5.6479 1 221125_WJC_METTL3_EV_vs_WT_F01.19947.19947.3 3.55E-08 17/56 R.LPLPSPALEYTLGSR.L sp|Q8IU81|I2BP1_HUMAN 1 1612.8825 1.36 7446 19947 3 1612.883909 538.6348 Interferon regulatory factor 2-binding protein 1 OS=Homo sapiens OX=9606 GN=IRF2BP1 PE=1 SV=1 6 3717.6 - 2.37E+06 - - - 0.8996 - 2.462 0.538 - 405.3 1 2 0 0.0015 15 0 0 0 1.30E+07 9.58E+06 - - - 6.8887 0.9983 221125_WJC_METTL3_EV_vs_WT_F01.19948.19948.2 0.000974 20-Nov R.ELGLGLGLGLK.E "sp|Q9BTD8|RBM42_HUMAN,tr|K7EQ03|K7EQ03_HUMAN,tr|K7ER08|K7ER08_HUMAN,tr|K7EP90|K7EP90_HUMAN" 4 1068.6543 1.12 7447 19948 2 1068.657992 535.3344 RNA-binding protein 42 OS=Homo sapiens OX=9606 GN=RBM42 PE=1 SV=1 6.1 3717.7 - 1.86E+06 - - - 3.4586 - 1.766 0.421 - 312.1 1 2 0 0.0037 11 0 0 0 8.74E+06 7.83E+06 - - - 3.6879 1 221125_WJC_METTL3_EV_vs_WT_F01.19949.19949.3 6.87E-05 17/56 R.LPLPSPALEYTLGSR[166.11].L sp|Q8IU81|I2BP1_HUMAN 1 1622.8907 1.36 7448 19949 3 1622.892648 541.9709 Interferon regulatory factor 2-binding protein 1 OS=Homo sapiens OX=9606 GN=IRF2BP1 PE=1 SV=1 6 3717.8 - 1.70E+06 - - - 1.1831 - 2.942 0.51 - 397.7 1 2 0 0.0019 15 0 0 0 1.30E+07 9.58E+06 - - - 7.0412 0.9999 221125_WJC_METTL3_EV_vs_WT_F01.19950.19950.2 3.07E-08 20-Nov K.DSLTLVFVETK.K "sp|O00571|DDX3X_HUMAN,sp|O15523|DDX3Y_HUMAN,tr|A0A2R8YFR4|A0A2R8YFR4_HUMAN,tr|A0A2R8YCW1|A0A2R8YCW1_HUMAN,tr|A0A2R8YDH3|A0A2R8YDH3_HUMAN,tr|A0A2R8YDT5|A0A2R8YDT5_HUMAN,tr|A0A2R8Y645|A0A2R8Y645_HUMAN,tr|A0A2R8YF78|A0A2R8YF78_HUMAN,tr|A0A0D9SFB3|A0A0D9SFB3_HUMAN,tr|A0A2R8YFS5|A0A2R8YFS5_HUMAN,tr|A0A0D9SF53|A0A0D9SF53_HUMAN,tr|A0A0J9YVQ7|A0A0J9YVQ7_HUMAN,tr|A0A2R8Y5G6|A0A2R8Y5G6_HUMAN,tr|A0A2R8Y7T2|A0A2R8Y7T2_HUMAN,tr|A0A0D9SG12|A0A0D9SG12_HUMAN,tr|F6S8Q4|F6S8Q4_HUMAN,tr|A0A2U3TZJ9|A0A2U3TZJ9_HUMAN,tr|A0A2R8Y4A4|A0A2R8Y4A4_HUMAN" 18 1250.6758 0.87 7449 19950 2 1250.675442 626.3452 ATP-dependent RNA helicase DDX3X OS=Homo sapiens OX=9606 GN=DDX3X PE=1 SV=3 4.37 3717.8 - 1.70E+06 - - - -0.3014 - 2.31 0.513 - 688.5 1 2 0 -0.0004 11 0 0 0 6.43E+06 7.42E+06 - - - 5.0949 0.9782 221125_WJC_METTL3_EV_vs_WT_F01.19952.19952.2 0.0224 12-Jul R.FVFLLDR.G sp|Q13045|FLII_HUMAN 1 908.512 0.82 7451 19952 2 908.513913 455.2633 Protein flightless-1 homolog OS=Homo sapiens OX=9606 GN=FLII PE=1 SV=2 5.84 3718.1 - 727339 - - - 2.1177 - 1.45 0.066 - 174.9 1 2 0 0.0019 7 0 0 0 5.93E+06 7.22E+06 - - - 0.7052 0.9992 221125_WJC_METTL3_EV_vs_WT_F01.19953.19953.2 0.0284 16-Aug R.ALQLLYDLR.Y "sp|Q8WTW3|COG1_HUMAN,tr|E9PBL8|E9PBL8_HUMAN,tr|A0A087WVI0|A0A087WVI0_HUMAN" 3 1103.6339 0.86 7452 19953 2 1103.634831 552.8242 Conserved oligomeric Golgi complex subunit 1 OS=Homo sapiens OX=9606 GN=COG1 PE=1 SV=1 5.88 3718.1 - 667255 - - - 0.8481 - 1.725 0.299 - 245.6 1 2 0 0.0009 9 0 0 0 3.54E+06 4.11E+06 - - - 2.8265 0.9998 221125_WJC_METTL3_EV_vs_WT_F01.19957.19957.2 1.57E-06 22-Dec K.C[160.03]PLDPYFIMPDK[136.11].C "sp|P33992|MCM5_HUMAN,tr|B1AHB1|B1AHB1_HUMAN,tr|B1AHB2|B1AHB2_HUMAN" 3 1502.7029 0.6 7456 19957 2 1502.705294 752.3587 DNA replication licensing factor MCM5 OS=Homo sapiens OX=9606 GN=MCM5 PE=1 SV=5 4.21 3718.7 - 536070 - - - 1.5871 - 2.174 0.52 - 331.1 1 2 0 0.0024 12 0 0 0 1.85E+06 3.09E+06 - - - 4.9243 0.9726 221125_WJC_METTL3_EV_vs_WT_F01.19960.19960.2 0.00263 12-May K.GC[160.03]C[160.03]FVTF.Y "sp|Q92879|CELF1_HUMAN,sp|O95319|CELF2_HUMAN,tr|F5H4Y5|F5H4Y5_HUMAN,tr|G5EA30|G5EA30_HUMAN,tr|E9PSH0|E9PSH0_HUMAN,tr|E9PC62|E9PC62_HUMAN,tr|E9PQK4|E9PQK4_HUMAN,tr|A0A1B0GU44|A0A1B0GU44_HUMAN,tr|E9PKU1|E9PKU1_HUMAN,tr|A0A0J9YX66|A0A0J9YX66_HUMAN,tr|A0A1B0GUN8|A0A1B0GUN8_HUMAN,tr|Q5VZZ6|Q5VZZ6_HUMAN,tr|A0A0J9YXJ0|A0A0J9YXJ0_HUMAN,tr|V9GYD9|V9GYD9_HUMAN,tr|F5H0D8|F5H0D8_HUMAN" 15 889.3462 - 7459 19960 2 889.347086 445.6804 CUGBP Elav-like family member 1 OS=Homo sapiens OX=9606 GN=CELF1 PE=1 SV=2 5.51 3719 - 475404 - - - 0.9445 - 1.146 0.526 - 77.9 1 1 0 0.0008 7 0 0 0 - - - - - 3.3576 0.9996 221125_WJC_METTL3_EV_vs_WT_F01.19961.19961.2 0.00179 18-Sep R.LFALVLTPTR.E sp|Q9H0S4|DDX47_HUMAN 1 1129.6859 0.72 7460 19961 2 1129.688023 565.8502 Probable ATP-dependent RNA helicase DDX47 OS=Homo sapiens OX=9606 GN=DDX47 PE=1 SV=1 9.75 3719.1 - 439036 - - - 1.8527 - 2.106 0.432 - 340.7 1 2 0 0.0021 10 0 0 0 2.53E+06 3.49E+06 - - - 4.31 0.9995 221125_WJC_METTL3_EV_vs_WT_F01.19962.19962.2 0.000388 24-Oct R.FSPLMTAAVLGTR.G "sp|Q6P996|PDXD1_HUMAN,tr|H3BND4|H3BND4_HUMAN" 2 1362.733 1.26 7461 19962 2 1362.735062 682.3738 Pyridoxal-dependent decarboxylase domain-containing protein 1 OS=Homo sapiens OX=9606 GN=PDXDC1 PE=1 SV=2 9.75 3719.3 - 426747 - - - 1.5447 - 1.713 0.439 - 93.8 1 2 0 0.0021 13 0 0 0 1.86E+06 1.48E+06 - - - 3.6642 0.9572 221125_WJC_METTL3_EV_vs_WT_F01.19965.19965.2 0.723 14-May -.MLPLSLLK.T "sp|Q9Y4Z0|LSM4_HUMAN,tr|M0QXB0|M0QXB0_HUMAN,tr|V9GZ56|V9GZ56_HUMAN" 3 913.5671 1.83 7463 19965 2 913.56774 457.7908 U6 snRNA-associated Sm-like protein LSm4 OS=Homo sapiens OX=9606 GN=LSM4 PE=1 SV=1 8.5 3719.6 - 864269 - - - 0.7432 - 0.975 0.16 - 60.5 7 2 0 0.0007 8 0 0 0 1.12E+07 6.10E+06 - - - -0.2313 0.9527 221125_WJC_METTL3_EV_vs_WT_F01.19967.19967.2 0.249 16-Sep S.ALAFEQIIK.N "sp|Q8NCM8|DYHC2_HUMAN,sp|Q15643|TRIPB_HUMAN,tr|A0A3B3IT36|A0A3B3IT36_HUMAN,tr|A0A3B3ISP9|A0A3B3ISP9_HUMAN,tr|H0YJ97|H0YJ97_HUMAN" 5 1031.6015 1.05 7465 19967 2 1031.602385 516.808 Cytoplasmic dynein 2 heavy chain 1 OS=Homo sapiens OX=9606 GN=DYNC2H1 PE=1 SV=4 6.05 3719.8 - 7.32E+06 - - - 0.8269 - 1.708 0.29 - 262.5 1 1 0 0.0009 9 0 0 0 8.80E+07 8.37E+07 - - - 2.7314 0.9999 221125_WJC_METTL3_EV_vs_WT_F01.19969.19969.2 1.47E-05 18-Oct K.MDMSLDDIIK.L "sp|Q86V81|THOC4_HUMAN,tr|E9PB61|E9PB61_HUMAN" 2 1179.5515 0.44 7467 19969 2 1179.551635 590.783 THO complex subunit 4 OS=Homo sapiens OX=9606 GN=ALYREF PE=1 SV=3 3.93 3719.9 - 4.45E+06 - - - 0.0746 - 2.047 0.493 - 325.4 1 2 0 0.0001 10 0 0 0 1.33E+07 3.01E+07 - - - 4.6819 0.9503 221125_WJC_METTL3_EV_vs_WT_F01.19971.19971.2 0.00499 20-Jul R.IHFPLATYAPV.L "sp|Q6PEY2|TBA3E_HUMAN,sp|P0DPH7|TBA3C_HUMAN,sp|Q71U36|TBA1A_HUMAN,sp|P0DPH8|TBA3D_HUMAN,sp|P68366|TBA4A_HUMAN,sp|P68363|TBA1B_HUMAN,sp|Q9BQE3|TBA1C_HUMAN,tr|F8VVB9|F8VVB9_HUMAN,tr|C9JDS9|C9JDS9_HUMAN,tr|A0A1W2PQM2|A0A1W2PQM2_HUMAN,tr|F5H5D3|F5H5D3_HUMAN" 11 1227.6652 - 7469 19971 2 1227.668256 614.8399 Tubulin alpha-3E chain OS=Homo sapiens OX=9606 GN=TUBA3E PE=1 SV=2 6.74 3720 - 1.15E+06 - - - 2.4934 - 1.739 0.428 - 101.8 1 1 0 0.0031 11 0 0 0 - - - - - 3.6981 0.9998 221125_WJC_METTL3_EV_vs_WT_F01.19972.19972.2 0.00113 16/26 K.ALLAVIGADSVTLK.N sp|Q9NYH9|UTP6_HUMAN 1 1369.8181 1.2 7470 19972 2 1369.818466 685.9163 U3 small nucleolar RNA-associated protein 6 homolog OS=Homo sapiens OX=9606 GN=UTP6 PE=1 SV=2 5.88 3720.1 - 935193 - - - 0.2913 - 2.827 0.336 - 1026.9 1 2 0 0.0004 14 0 0 0 3.52E+06 2.93E+06 - - - 4.1304 0.9996 221125_WJC_METTL3_EV_vs_WT_F01.19975.19975.2 0.00714 24-Oct R.YWLEGGSLLGAAR.H sp|Q9H9S5|FKRP_HUMAN 1 1391.7197 6.6 7473 19975 2 1391.721487 696.8672 Fukutin-related protein OS=Homo sapiens OX=9606 GN=FKRP PE=1 SV=1 6 3720.5 - 510531 - - - 1.2481 - 1.956 0.384 - 309.9 1 2 0 0.0017 13 0 0 0 1.56E+06 2.36E+05 - - - 3.5986 0.9694 221125_WJC_METTL3_EV_vs_WT_F01.19980.19980.2 0.000197 22-Nov A.GIPNLITADMIK[136.11].E "sp|P13995|MTDC_HUMAN,tr|A0A7I2V482|A0A7I2V482_HUMAN,tr|A0A7I2V2U6|A0A7I2V2U6_HUMAN,tr|A0A7I2YQD4|A0A7I2YQD4_HUMAN,tr|B9A062|B9A062_HUMAN" 5 1292.7254 0.73 7478 19980 2 1292.724307 647.37 "Bifunctional methylenetetrahydrofolate dehydrogenase\cyclohydrolase, mitochondrial OS=Homo sapiens OX=9606 GN=MTHFD2 PE=1 SV=2" 5.84 3721.1 - 354392 - - - -0.8138 - 1.889 0.321 - 308.2 1 1 0 -0.0011 12 0 0 0 1.42E+06 1.94E+06 - - - 3.0851 0.9999 221125_WJC_METTL3_EV_vs_WT_F01.19981.19981.2 5.29E-05 24-Oct M.PLVVFC[160.03]GLPYSGK[136.11].S sp|Q96EK9|KTI12_HUMAN 1 1443.7676 -1 7479 19981 2 1443.766223 722.8911 Protein KTI12 homolog OS=Homo sapiens OX=9606 GN=KTI12 PE=1 SV=1 8.6 3721.3 - 352306 - - - -0.9247 - 2.293 0.55 - 261.3 1 2 0 -0.0013 13 0 0 0 0.00E+00 0.00E+00 - - - 5.2327 0.9998 221125_WJC_METTL3_EV_vs_WT_F01.19982.19982.2 9.70E-06 22-Oct K.EVDNLYNIEILR.L sp|Q53HL2|BOREA_HUMAN 1 1489.7777 -1 7480 19982 2 1489.77823 745.8961 Borealin OS=Homo sapiens OX=9606 GN=CDCA8 PE=1 SV=2 4.14 3721.4 - 296258 - - - 0.3833 - 2.329 0.362 - 387.9 1 2 0 0.0006 12 0 0 0 0.00E+00 0.00E+00 - - - 3.939 0.9997 221125_WJC_METTL3_EV_vs_WT_F01.19983.19983.2 0.0605 22-Aug R.QELIALYGYDIR.S "sp|O15234|CASC3_HUMAN,tr|J3KSY7|J3KSY7_HUMAN" 2 1452.7613 -1 7481 19983 2 1452.762301 727.3879 Protein CASC3 OS=Homo sapiens OX=9606 GN=CASC3 PE=1 SV=2 4.37 3721.5 - 296045 - - - 0.7028 - 1.89 0.39 - 206.5 1 2 0 0.001 12 0 0 0 0.00E+00 0.00E+00 - - - 3.5962 1 221125_WJC_METTL3_EV_vs_WT_F01.19984.19984.2 0.000167 14/24 M.PLVVFC[160.03]GLPYSGK.S sp|Q96EK9|KTI12_HUMAN 1 1435.7534 -1 7482 19984 2 1435.754215 718.884 Protein KTI12 homolog OS=Homo sapiens OX=9606 GN=KTI12 PE=1 SV=1 8.6 3721.7 - 248375 - - - 0.5969 - 2.774 0.617 - 575.9 1 2 0 0.0009 13 0 0 0 0.00E+00 0.00E+00 - - - 6.2165 0.9998 221125_WJC_METTL3_EV_vs_WT_F01.19988.19988.2 0.00159 13/20 R.AFITNIPFDVK[136.11].W "sp|P52272|HNRPM_HUMAN,tr|M0R019|M0R019_HUMAN,tr|M0R0Y6|M0R0Y6_HUMAN,tr|M0R0N3|M0R0N3_HUMAN,tr|A0A087X0X3|A0A087X0X3_HUMAN,tr|M0QYQ7|M0QYQ7_HUMAN,tr|M0R2T0|M0R2T0_HUMAN" 7 1271.7005 1.73 7485 19988 2 1271.701461 636.8575 Heterogeneous nuclear ribonucleoprotein M OS=Homo sapiens OX=9606 GN=HNRNPM PE=1 SV=3 5.88 3722.2 - 3.85E+06 - - - 0.7368 - 2.301 0.458 - 654.1 1 2 0 0.0009 11 0 0 0 9.94E+08 5.73E+08 - - - 4.6779 0.9997 221125_WJC_METTL3_EV_vs_WT_F01.19990.19990.2 1.47E-05 12-Sep R.YMDLLWR.Y "sp|O75694|NU155_HUMAN,tr|E9PF10|E9PF10_HUMAN" 2 995.4899 1.26 7487 19990 2 995.490135 498.7522 Nuclear pore complex protein Nup155 OS=Homo sapiens OX=9606 GN=NUP155 PE=1 SV=1 5.84 3722.4 - 1.08E+06 - - - 0.2632 - 1.495 0.473 - 343.4 1 2 0 0.0003 7 0 0 0 3.74E+06 2.96E+06 - - - 3.8087 0.9949 221125_WJC_METTL3_EV_vs_WT_F01.19991.19991.2 0.0313 14-Sep K.NFLSTLIK[136.11].L sp|O00268|TAF4_HUMAN 1 942.563 1.93 7488 19991 2 942.562884 472.2888 Transcription initiation factor TFIID subunit 4 OS=Homo sapiens OX=9606 GN=TAF4 PE=1 SV=2 8.75 3722.5 - 885544 - - - -0.0891 - 1.497 0.112 - 305.8 1 2 0 -0.0001 8 0 0 0 1.81E+07 9.36E+06 - - - 1.085 0.8645 221125_WJC_METTL3_EV_vs_WT_F01.19992.19992.2 0.111 12-Jun R.TFHIFYY.M "sp|P35749|MYH11_HUMAN,sp|P35579|MYH9_HUMAN,tr|A0A494C024|A0A494C024_HUMAN" 3 989.4647 - 7489 19992 2 989.464029 495.7396 Myosin-11 OS=Homo sapiens OX=9606 GN=MYH11 PE=1 SV=3 6.4 3722.6 - 843021 - - - -0.6822 - 1.123 0.302 - 116.1 1 1 0 -0.0007 7 0 0 0 - - - - - 1.6389 0.9998 221125_WJC_METTL3_EV_vs_WT_F01.19993.19993.2 1.25E-05 12-Sep R.YMDLLWR[166.11].Y "sp|O75694|NU155_HUMAN,tr|E9PF10|E9PF10_HUMAN" 2 1005.4981 1.44 7490 19993 2 1005.498742 503.7563 Nuclear pore complex protein Nup155 OS=Homo sapiens OX=9606 GN=NUP155 PE=1 SV=1 5.84 3722.7 - 802733 - - - 0.5957 - 1.619 0.543 - 335.5 1 2 0 0.0006 7 0 0 0 3.71E+06 2.58E+06 - - - 4.578 0.9999 221125_WJC_METTL3_EV_vs_WT_F01.19994.19994.2 4.72E-07 16-Nov R.WGYWGSWGK.S "sp|Q9NRY5|F1142_HUMAN,tr|E5RHI8|E5RHI8_HUMAN,tr|E5RHP2|E5RHP2_HUMAN,tr|E5RGF9|E5RGF9_HUMAN,tr|E5RFK2|E5RFK2_HUMAN" 5 1125.5032 1.39 7491 19994 2 1125.504394 563.7589 Protein FAM114A2 OS=Homo sapiens OX=9606 GN=FAM114A2 PE=1 SV=4 8.59 3722.8 - 801092 - - - 1.0475 - 2.078 0.611 - 425.7 1 2 0 0.0012 9 0 0 0 4.97E+06 3.58E+06 - - - 5.6695 0.9997 221125_WJC_METTL3_EV_vs_WT_F01.19995.19995.2 0.179 14/26 K.ALLAVIGADSVTLK[136.11].N sp|Q9NYH9|UTP6_HUMAN 1 1377.8323 1.2 7492 19995 2 1377.831758 689.9234 U3 small nucleolar RNA-associated protein 6 homolog OS=Homo sapiens OX=9606 GN=UTP6 PE=1 SV=2 5.88 3723 - 774882 - - - -0.3694 - 2.606 0.297 - 680.4 1 2 0 -0.0005 14 0 0 0 3.52E+06 2.93E+06 - - - 3.6381 0.9999 221125_WJC_METTL3_EV_vs_WT_F01.19996.19996.2 0.000143 16-Aug R.WGYWGSWGK[136.11].S "sp|Q9NRY5|F1142_HUMAN,tr|E5RHI8|E5RHI8_HUMAN,tr|E5RHP2|E5RHP2_HUMAN,tr|E5RGF9|E5RGF9_HUMAN,tr|E5RFK2|E5RFK2_HUMAN" 5 1133.5174 1.39 7493 19996 2 1133.516781 567.766 Protein FAM114A2 OS=Homo sapiens OX=9606 GN=FAM114A2 PE=1 SV=4 8.59 3723.1 - 655811 - - - -0.5593 - 1.808 0.531 - 183.8 1 2 0 -0.0006 9 0 0 0 4.97E+06 3.58E+06 - - - 4.6761 0.9996 221125_WJC_METTL3_EV_vs_WT_F01.19998.19998.2 0.00123 18-Sep R.LFALVLTPTR[166.11].E sp|Q9H0S4|DDX47_HUMAN 1 1139.6942 0.72 7495 19998 2 1139.696042 570.8544 Probable ATP-dependent RNA helicase DDX47 OS=Homo sapiens OX=9606 GN=DDX47 PE=1 SV=1 9.75 3723.4 - 573986 - - - 1.6162 - 1.945 0.399 - 235.7 1 2 0 0.0018 10 0 0 0 2.53E+06 3.49E+06 - - - 3.8444 0.9997 221125_WJC_METTL3_EV_vs_WT_F01.20007.20007.2 0.00479 20-Nov K.LALDIEIATYR.K "sp|P14136|GFAP_HUMAN,sp|Q6KB66|K2C80_HUMAN,sp|P05787|K2C8_HUMAN,sp|P19013|K2C4_HUMAN,sp|P04264|K2C1_HUMAN,sp|P08729|K2C7_HUMAN,tr|A0A1W2PR46|A0A1W2PR46_HUMAN,tr|A0A1X7SBR3|A0A1X7SBR3_HUMAN,tr|A0A1W2PQU7|A0A1W2PQU7_HUMAN,tr|K7EJU1|K7EJU1_HUMAN,tr|A0A1X7SCE1|A0A1X7SCE1_HUMAN,tr|A0A1W2PRT3|A0A1W2PRT3_HUMAN,tr|A0A1W2PS58|A0A1W2PS58_HUMAN,tr|K7EPI4|K7EPI4_HUMAN" 14 1276.7027 67.37 7503 20007 2 1276.702572 639.3586 Glial fibrillary acidic protein OS=Homo sapiens OX=9606 GN=GFAP PE=1 SV=1 4.37 3724.5 - 4.63E+06 - - - -0.1026 - 2.283 0.325 - 414.7 1 2 0 -0.0001 11 0 0 0 8.79E+07 1.30E+06 - - - 3.6746 0.9994 221125_WJC_METTL3_EV_vs_WT_F01.20009.20009.2 0.108 16-Aug K.LEATINELV.- sp|P10599|THIO_HUMAN 1 1000.5441 - 7505 20009 2 1000.544342 501.2793 Thioredoxin OS=Homo sapiens OX=9606 GN=TXN PE=1 SV=3 3.79 3724.6 - 9.93E+06 - - - 0.2649 - 1.536 0.343 - 144.2 1 2 0 0.0003 9 0 0 0 - - - - - 2.816 0.8062 221125_WJC_METTL3_EV_vs_WT_F01.20010.20010.2 0.41 18-Jun K.AFYPEEISSM.V "sp|P0DMV8|HS71A_HUMAN,sp|P34931|HS71L_HUMAN,sp|P0DMV9|HS71B_HUMAN,tr|Q53FA3|Q53FA3_HUMAN,tr|A0A0G2JIW1|A0A0G2JIW1_HUMAN" 5 1172.506 - 7506 20010 2 1172.506625 587.2603 Heat shock 70 kDa protein 1A OS=Homo sapiens OX=9606 GN=HSPA1A PE=1 SV=1 3.8 3724.7 - 6.90E+06 - - - 0.5527 - 0.983 0.318 - 118 1 1 0 0.0006 10 0 0 0 - - - - - 1.3417 0.9997 221125_WJC_METTL3_EV_vs_WT_F01.20011.20011.2 0.00366 14-Aug R.GFC[160.03]FITFK[136.11].E "sp|Q14103|HNRPD_HUMAN,tr|H0Y8G5|H0Y8G5_HUMAN,tr|H0YA96|H0YA96_HUMAN" 3 1026.5088 1.43 7507 20011 2 1026.509403 514.2617 Heterogeneous nuclear ribonucleoprotein D0 OS=Homo sapiens OX=9606 GN=HNRNPD PE=1 SV=1 8.22 3724.7 - 6.88E+06 - - - 0.564 - 1.549 0.45 - 260.3 1 2 0 0.0006 8 0 0 0 7.18E+07 5.02E+07 - - - 3.6843 0.9997 221125_WJC_METTL3_EV_vs_WT_F01.20012.20012.2 0.000446 14-Aug R.GFC[160.03]FITFK.E "sp|Q14103|HNRPD_HUMAN,tr|H0Y8G5|H0Y8G5_HUMAN,tr|H0YA96|H0YA96_HUMAN" 3 1018.4946 1.43 7508 20012 2 1018.495392 510.2546 Heterogeneous nuclear ribonucleoprotein D0 OS=Homo sapiens OX=9606 GN=HNRNPD PE=1 SV=1 8.22 3724.8 - 6.53E+06 - - - 0.7541 - 1.541 0.495 - 250.8 1 2 0 0.0008 8 0 0 0 7.18E+07 5.02E+07 - - - 4.001 0.9998 221125_WJC_METTL3_EV_vs_WT_F01.20013.20013.2 0.00649 20-Dec R.LLGDLLPEAVR.F sp|Q9H1B7|I2BPL_HUMAN 1 1194.6972 3.41 7509 20013 2 1194.697112 598.3559 Probable E3 ubiquitin-protein ligase IRF2BPL OS=Homo sapiens OX=9606 GN=IRF2BPL PE=1 SV=1 4.37 3724.8 - 3.87E+06 - - - -0.0929 - 2.174 0.359 - 361.3 1 2 0 -0.0001 11 0 0 0 2.55E+07 7.49E+06 - - - 3.7933 0.9981 221125_WJC_METTL3_EV_vs_WT_F01.20014.20014.3 3.12E-08 14/56 L.LVSVSALTLATETVR[166.11].S sp|P50991|TCPD_HUMAN 1 1568.9013 1.18 7510 20014 3 1568.900775 523.9744 T-complex protein 1 subunit delta OS=Homo sapiens OX=9606 GN=CCT4 PE=1 SV=4 6 3724.9 - 3.69E+06 - - - -0.3302 - 2.772 0.539 - 232.8 1 1 0 -0.0005 15 0 0 0 1.79E+07 1.51E+07 - - - 7.2096 0.9988 221125_WJC_METTL3_EV_vs_WT_F01.20015.20015.2 0.0217 20-Oct R.VLPSIVNEVLK.S "sp|Q99623|PHB2_HUMAN,tr|F5H3X6|F5H3X6_HUMAN,tr|A0A7I2V5F0|A0A7I2V5F0_HUMAN,tr|F5GWA7|F5GWA7_HUMAN,tr|J3KPX7|J3KPX7_HUMAN,tr|F5GY37|F5GY37_HUMAN" 6 1209.7333 1.17 7511 20015 2 1209.735643 605.8739 Prohibitin-2 OS=Homo sapiens OX=9606 GN=PHB2 PE=1 SV=2 5.97 3725 - 1.38E+06 - - - 1.9575 - 1.479 0.382 - 192.3 1 2 0 0.0024 11 0 0 0 2.57E+08 2.19E+08 - - - 2.9204 0.9994 221125_WJC_METTL3_EV_vs_WT_F01.20016.20016.2 2.71E-07 13/26 K.LLTGELLPTDGMIR.K sp|Q9UG63|ABCF2_HUMAN 1 1527.8331 0.48 7512 20016 2 1527.836482 764.9238 ATP-binding cassette sub-family F member 2 OS=Homo sapiens OX=9606 GN=ABCF2 PE=1 SV=2 4.37 3725.1 - 884814 - - - 2.2365 - 2.579 0.357 - 408.7 1 2 0 0.0034 14 0 0 0 3.90E+06 8.14E+06 - - - 4.0542 0.9999 221125_WJC_METTL3_EV_vs_WT_F01.20017.20017.2 3.19E-07 22-Nov R.LFTNFSGADLLK[136.11].L "sp|Q12800|TFCP2_HUMAN,tr|F8VWL0|F8VWL0_HUMAN" 2 1332.7169 1.99 7513 20017 2 1332.716516 667.3657 Alpha-globin transcription factor CP2 OS=Homo sapiens OX=9606 GN=TFCP2 PE=1 SV=2 5.84 3725.2 - 878706 - - - -0.2904 - 2.38 0.504 - 270.3 1 2 0 -0.0004 12 0 0 0 9.76E+06 4.90E+06 - - - 5.0449 0.9993 221125_WJC_METTL3_EV_vs_WT_F01.20020.20020.2 2.61 14-Oct R.LLNLELLR.Q sp|Q5JXC2|MIIP_HUMAN 1 982.6175 3.72 7516 20020 2 982.618337 492.316 Migration and invasion-inhibitory protein OS=Homo sapiens OX=9606 GN=MIIP PE=1 SV=3 6 3725.6 - 732992 - - - 0.8355 - 2.059 0.219 - 232.6 1 2 0 0.0008 8 0 0 0 2.54E+06 6.82E+05 - - - 2.8365 0.9999 221125_WJC_METTL3_EV_vs_WT_F01.20021.20021.2 0.000206 22-Nov R.LFTNFSGADLLK.L "sp|Q12800|TFCP2_HUMAN,tr|F8VWL0|F8VWL0_HUMAN" 2 1324.7027 1.09 7517 20021 2 1324.70228 663.3586 Alpha-globin transcription factor CP2 OS=Homo sapiens OX=9606 GN=TFCP2 PE=1 SV=2 5.84 3725.7 - 698054 - - - -0.3193 - 2.375 0.451 - 309.2 1 2 0 -0.0004 12 0 0 0 5.09E+06 4.68E+06 - - - 4.6479 0.9997 221125_WJC_METTL3_EV_vs_WT_F01.20024.20024.2 0.000662 20-Nov K.IGDLGLATLMR.T "sp|Q9BYP7|WNK3_HUMAN,tr|A0A087WYK2|A0A087WYK2_HUMAN" 2 1158.6431 1.26 7520 20024 2 1158.641539 580.3288 Serine\threonine-protein kinase WNK3 OS=Homo sapiens OX=9606 GN=WNK3 PE=1 SV=3 5.84 3726.1 - 428813 - - - -1.3291 - 2.336 0.344 - 293.9 1 2 0 -0.0015 11 0 0 0 1.91E+06 1.52E+06 - - - 3.8765 0.9999 221125_WJC_METTL3_EV_vs_WT_F01.20030.20030.2 1.04E-06 20-Dec R.FSYLAVIEGAK.F "sp|P18031|PTN1_HUMAN,tr|B4DSN5|B4DSN5_HUMAN" 2 1196.6441 1.33 7525 20030 2 1196.644682 599.3293 Tyrosine-protein phosphatase non-receptor type 1 OS=Homo sapiens OX=9606 GN=PTPN1 PE=1 SV=1 6 3726.7 - 3.15E+06 - - - 0.4655 - 2.367 0.48 - 417.5 1 2 0 0.0006 11 0 0 0 1.04E+07 7.77E+06 - - - 4.917 0.9985 221125_WJC_METTL3_EV_vs_WT_F01.20031.20031.2 0.00358 20-Oct R.VLPSIVNEVLK[136.11].S "sp|Q99623|PHB2_HUMAN,tr|F5H3X6|F5H3X6_HUMAN,tr|A0A7I2V5F0|A0A7I2V5F0_HUMAN,tr|F5GWA7|F5GWA7_HUMAN,tr|J3KPX7|J3KPX7_HUMAN,tr|F5GY37|F5GY37_HUMAN" 6 1217.7475 1.17 7526 20031 2 1217.749521 609.881 Prohibitin-2 OS=Homo sapiens OX=9606 GN=PHB2 PE=1 SV=2 5.97 3726.8 - 1.37E+06 - - - 1.6802 - 2.079 0.21 - 302 1 2 0 0.002 11 0 0 0 2.57E+08 2.19E+08 - - - 2.5713 1 221125_WJC_METTL3_EV_vs_WT_F01.20033.20033.2 8.13E-09 24-Dec K.ELAPYDENWFYTR.A "sp|P39019|RS19_HUMAN,tr|M0R140|M0R140_HUMAN,tr|M0R2L9|M0R2L9_HUMAN,tr|M0QYF7|M0QYF7_HUMAN" 4 1702.7627 1.43 7528 20033 2 1702.759009 852.3886 40S ribosomal protein S19 OS=Homo sapiens OX=9606 GN=RPS19 PE=1 SV=2 4.14 3727 - 1.14E+06 - - - -2.1894 - 2.533 0.657 - 609.9 1 2 0 -0.0037 13 0 0 0 8.62E+06 6.02E+06 - - - 6.2778 0.9986 221125_WJC_METTL3_EV_vs_WT_F01.20034.20034.3 2.80E-09 19/76 K.HAASDVDLEIESLLNQQSTK[136.11].E "sp|Q86U44|MTA70_HUMAN,tr|F5H6D8|F5H6D8_HUMAN,tr|H0YFV6|H0YFV6_HUMAN,tr|B4DTN4|B4DTN4_HUMAN" 4 2205.1005 -1 7529 20034 3 2206.096757 736.0408 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 4.31 3727.1 - 845282 - - - 451.8166 - 3.419 0.607 - 369.1 1 2 0 0.9963 20 0 0 0 0.00E+00 0.00E+00 - - - 8.0139 0.9999 221125_WJC_METTL3_EV_vs_WT_F01.20035.20035.2 2.44E-08 24-Dec K.ELAPYDENWFYTR[166.11].A "sp|P39019|RS19_HUMAN,tr|M0R140|M0R140_HUMAN,tr|M0R2L9|M0R2L9_HUMAN,tr|M0QYF7|M0QYF7_HUMAN" 4 1712.771 1.43 7530 20035 2 1712.769506 857.3928 40S ribosomal protein S19 OS=Homo sapiens OX=9606 GN=RPS19 PE=1 SV=2 4.14 3727.3 - 825460 - - - -0.8764 - 2.389 0.6 - 618 1 2 0 -0.0015 13 0 0 0 8.62E+06 6.02E+06 - - - 5.7073 0.9982 221125_WJC_METTL3_EV_vs_WT_F01.20047.20047.2 0.0601 28-Jul R.LTPSASLPPAQLLLR.A "sp|P06576|ATPB_HUMAN,tr|F8W079|F8W079_HUMAN,tr|F8W0P7|F8W0P7_HUMAN,tr|H0YH81|H0YH81_HUMAN" 4 1575.9348 2.16 7541 20047 2 1575.932161 788.9747 "ATP synthase subunit beta, mitochondrial OS=Homo sapiens OX=9606 GN=ATP5F1B PE=1 SV=3" 9.75 3728.8 - 360537 - - - -1.6923 - 1.592 0.294 - 81.7 1 2 0 -0.0027 15 0 0 0 1.99E+06 9.21E+05 - - - 2.3548 0.9998 221125_WJC_METTL3_EV_vs_WT_F01.20048.20048.2 0.000172 18-Oct K.LTLSALIDGK.N "sp|Q9Y277|VDAC3_HUMAN,sp|P21796|VDAC1_HUMAN" 2 1029.607 1.41 7542 20048 2 1029.60599 515.8108 Voltage-dependent anion-selective channel protein 3 OS=Homo sapiens OX=9606 GN=VDAC3 PE=1 SV=1 5.84 3728.8 - 1.61E+07 - - - -0.9916 - 2.15 0.48 - 296.2 1 2 0 -0.001 10 0 0 0 6.13E+07 4.35E+07 - - - 4.7226 0.9999 221125_WJC_METTL3_EV_vs_WT_F01.20050.20050.2 7.15E-08 22-Nov K.MFIGGLSWDTTK.K "sp|Q14103|HNRPD_HUMAN,tr|H0Y8G5|H0Y8G5_HUMAN,tr|D6RF44|D6RF44_HUMAN,tr|D6RD83|D6RD83_HUMAN,tr|D6RBQ9|D6RBQ9_HUMAN,tr|D6RAF8|D6RAF8_HUMAN,tr|H0YA96|H0YA96_HUMAN" 7 1354.6591 1.39 7544 20050 2 1354.658438 678.3368 Heterogeneous nuclear ribonucleoprotein D0 OS=Homo sapiens OX=9606 GN=HNRNPD PE=1 SV=1 5.59 3728.9 - 2.58E+06 - - - -0.5057 - 2.172 0.603 - 304.5 1 2 0 -0.0007 12 0 0 0 2.37E+07 1.71E+07 - - - 5.5354 0.9872 221125_WJC_METTL3_EV_vs_WT_F01.20051.20051.2 0.00961 14-Sep K.QFLPFLQR[166.11].A "sp|Q7KZF4|SND1_HUMAN,tr|H7C597|H7C597_HUMAN" 2 1057.5948 1.01 7545 20051 2 1057.601217 529.8047 Staphylococcal nuclease domain-containing protein 1 OS=Homo sapiens OX=9606 GN=SND1 PE=1 SV=1 9.75 3729 - 2.04E+06 - - - 6.0477 - 1.796 0.364 - 274.5 1 2 0 0.0064 8 0 0 0 1.70E+07 1.69E+07 - - - 3.4935 0.9999 221125_WJC_METTL3_EV_vs_WT_F01.20052.20052.2 0.000498 22-Dec K.MFIGGLSWDTTK[136.11].K "sp|Q14103|HNRPD_HUMAN,tr|H0Y8G5|H0Y8G5_HUMAN,tr|D6RF44|D6RF44_HUMAN,tr|D6RD83|D6RD83_HUMAN,tr|D6RBQ9|D6RBQ9_HUMAN,tr|D6RAF8|D6RAF8_HUMAN,tr|H0YA96|H0YA96_HUMAN" 7 1362.6733 1.39 7546 20052 2 1362.672355 682.3439 Heterogeneous nuclear ribonucleoprotein D0 OS=Homo sapiens OX=9606 GN=HNRNPD PE=1 SV=1 5.59 3729 - 1.90E+06 - - - -0.7104 - 2.037 0.533 - 345.1 1 2 0 -0.001 12 0 0 0 2.37E+07 1.71E+07 - - - 4.8495 0.9996 221125_WJC_METTL3_EV_vs_WT_F01.20053.20053.2 0.00693 18-Sep R.EYLLDMIPPR.S "sp|Q86YP4|P66A_HUMAN,sp|Q8WXI9|P66B_HUMAN,tr|A0A0U1RRM1|A0A0U1RRM1_HUMAN" 3 1245.6427 2.23 7547 20053 2 1245.643823 623.8286 Transcriptional repressor p66-alpha OS=Homo sapiens OX=9606 GN=GATAD2A PE=1 SV=1 4.37 3729.1 - 1.31E+06 - - - 0.8654 - 1.782 0.375 - 354.3 1 2 0 0.0011 10 0 0 0 1.63E+07 7.31E+06 - - - 3.423 0.9977 221125_WJC_METTL3_EV_vs_WT_F01.20054.20054.2 0.00321 18-Oct K.LQDMLDGFIK.K "sp|P55010|IF5_HUMAN,tr|H0YM54|H0YM54_HUMAN,tr|H0YLZ1|H0YLZ1_HUMAN,tr|H0YMJ8|H0YMJ8_HUMAN,tr|H0YN40|H0YN40_HUMAN" 5 1178.6005 -1 7548 20054 2 1178.603726 590.3075 Eukaryotic translation initiation factor 5 OS=Homo sapiens OX=9606 GN=EIF5 PE=1 SV=2 4.21 3729.2 - 1.15E+06 - - - 2.6981 - 1.558 0.341 - 232.7 1 2 0 0.0032 10 0 0 0 0.00E+00 0.00E+00 - - - 2.7963 0.9991 221125_WJC_METTL3_EV_vs_WT_F01.20056.20056.3 0.00274 Nov-40 R.AFITNIPFDVK[136.11].W "sp|P52272|HNRPM_HUMAN,tr|M0R019|M0R019_HUMAN,tr|M0R0Y6|M0R0Y6_HUMAN,tr|M0R0N3|M0R0N3_HUMAN,tr|A0A087X0X3|A0A087X0X3_HUMAN,tr|M0QYQ7|M0QYQ7_HUMAN,tr|M0R2T0|M0R2T0_HUMAN" 7 1271.7005 1.68 7550 20056 3 1271.695961 424.9075 Heterogeneous nuclear ribonucleoprotein M OS=Homo sapiens OX=9606 GN=HNRNPM PE=1 SV=3 5.88 3729.4 - 795858 - - - -3.5881 - 1.886 0.398 - 195.4 1 2 0 -0.0046 11 0 0 0 7.16E+06 4.25E+06 - - - 4.7784 0.9997 221125_WJC_METTL3_EV_vs_WT_F01.20058.20058.2 2.59E-05 18-Oct K.NGFLLDGFPR[166.11].T "sp|P54819|KAD2_HUMAN,tr|A0A5F9ZHP2|A0A5F9ZHP2_HUMAN,tr|G3V213|G3V213_HUMAN,tr|F8VY04|F8VY04_HUMAN,tr|F8W1A4|F8W1A4_HUMAN,tr|A0A5K1VW67|A0A5K1VW67_HUMAN,tr|F8VZG5|F8VZG5_HUMAN" 7 1144.5905 1.17 7552 20058 2 1144.592351 573.3025 "Adenylate kinase 2, mitochondrial OS=Homo sapiens OX=9606 GN=AK2 PE=1 SV=2" 5.84 3729.7 - 596401 - - - 1.6486 - 1.905 0.505 - 312.7 1 2 0 0.0019 10 0 0 0 8.33E+06 7.11E+06 - - - 4.5693 0.9997 221125_WJC_METTL3_EV_vs_WT_F01.20059.20059.2 0.000158 18-Sep K.MVYLLEC[160.03]LQK.T sp|Q9UJV9|DDX41_HUMAN 1 1295.6618 0.83 7553 20059 2 1295.660915 648.8382 Probable ATP-dependent RNA helicase DDX41 OS=Homo sapiens OX=9606 GN=DDX41 PE=1 SV=2 5.75 3729.8 - 572315 - - - -0.6568 - 1.915 0.37 - 277.6 1 2 0 -0.0009 10 0 0 0 2.63E+06 3.16E+06 - - - 3.5871 0.9248 221125_WJC_METTL3_EV_vs_WT_F01.20064.20064.2 0.000802 24-Aug K.NLPLGWDGK[136.11]PIPY.W sp|Q12874|SF3A3_HUMAN 1 1476.7857 2.17 7558 20064 2 1476.783496 739.4001 Splicing factor 3A subunit 3 OS=Homo sapiens OX=9606 GN=SF3A3 PE=1 SV=1 5.83 3730.5 - 229266 - - - -1.4593 - 1.32 0.368 - 117 1 1 0 -0.0022 13 0 0 0 9.19E+06 4.23E+06 - - - 2.4709 0.9998 221125_WJC_METTL3_EV_vs_WT_F01.20066.20066.2 0.00018 20-Sep R.FSYLAVIEGAK[136.11].F "sp|P18031|PTN1_HUMAN,tr|B4DSN5|B4DSN5_HUMAN" 2 1204.6583 1.33 7559 20066 2 1204.658187 603.3364 Tyrosine-protein phosphatase non-receptor type 1 OS=Homo sapiens OX=9606 GN=PTPN1 PE=1 SV=1 6 3730.8 - 369400 - - - -0.1146 - 1.921 0.441 - 165.6 1 2 0 -0.0001 11 0 0 0 1.04E+07 7.77E+06 - - - 4.0643 0.9997 221125_WJC_METTL3_EV_vs_WT_F01.20068.20068.2 0.0116 14-Sep K.VNLAELFK.G sp|P30044|PRDX5_HUMAN 1 932.5331 1.39 7561 20068 2 932.53236 467.2738 "Peroxiredoxin-5, mitochondrial OS=Homo sapiens OX=9606 GN=PRDX5 PE=1 SV=4" 5.97 3731 - 9.85E+06 - - - -0.8128 - 2.067 0.347 - 285.2 1 2 0 -0.0008 8 0 0 0 1.78E+08 1.28E+08 - - - 3.7936 0.9996 221125_WJC_METTL3_EV_vs_WT_F01.20069.20069.2 0.259 14-Aug K.VNLAELFK[136.11].G sp|P30044|PRDX5_HUMAN 1 940.5473 1.39 7562 20069 2 940.546425 471.2809 "Peroxiredoxin-5, mitochondrial OS=Homo sapiens OX=9606 GN=PRDX5 PE=1 SV=4" 5.97 3731 - 8.15E+06 - - - -0.9494 - 1.91 0.33 - 202.5 1 2 0 -0.0009 8 0 0 0 1.77E+08 1.28E+08 - - - 3.4297 0.9986 221125_WJC_METTL3_EV_vs_WT_F01.20071.20071.2 0.0101 14-Sep K.QFLPFLQR.A "sp|Q7KZF4|SND1_HUMAN,tr|H7C597|H7C597_HUMAN" 2 1047.5866 0.74 7564 20071 2 1047.588435 524.8006 Staphylococcal nuclease domain-containing protein 1 OS=Homo sapiens OX=9606 GN=SND1 PE=1 SV=1 9.75 3731.1 - 2.22E+06 - - - 1.7984 - 1.481 0.333 - 249.7 1 2 0 0.0019 8 0 0 0 1.25E+07 1.69E+07 - - - 2.6844 0.9976 221125_WJC_METTL3_EV_vs_WT_F01.20073.20073.2 0.000613 22-Oct K.FLQDTIEEMALK.N sp|O95202|LETM1_HUMAN 1 1436.7221 1.06 7566 20073 2 1436.717703 719.3683 Mitochondrial proton\calcium exchanger protein OS=Homo sapiens OX=9606 GN=LETM1 PE=1 SV=1 4.14 3731.3 - 1.36E+06 - - - -3.073 - 1.87 0.314 - 273.1 1 2 0 -0.0044 12 0 0 0 7.54E+06 7.10E+06 - - - 3.0058 0.9994 221125_WJC_METTL3_EV_vs_WT_F01.20074.20074.3 0.0268 Nov-40 R.AFITNIPFDVK.W "sp|P52272|HNRPM_HUMAN,tr|M0R019|M0R019_HUMAN,tr|M0R0Y6|M0R0Y6_HUMAN,tr|M0R0N3|M0R0N3_HUMAN,tr|A0A087X0X3|A0A087X0X3_HUMAN,tr|M0QYQ7|M0QYQ7_HUMAN,tr|M0R2T0|M0R2T0_HUMAN" 7 1263.6863 1.59 7567 20074 3 1263.685621 422.2361 Heterogeneous nuclear ribonucleoprotein M OS=Homo sapiens OX=9606 GN=HNRNPM PE=1 SV=3 5.88 3731.4 - 1.29E+06 - - - -0.5563 - 2.055 0.273 - 213.4 1 2 0 -0.0007 11 0 0 0 7.23E+06 4.54E+06 - - - 3.6297 0.9997 221125_WJC_METTL3_EV_vs_WT_F01.20075.20075.2 0.000486 13/20 K.GLAGAVSELLR[166.11].S sp|Q9Y490|TLN1_HUMAN 1 1094.6323 1.52 7568 20075 2 1094.63431 548.3234 Talin-1 OS=Homo sapiens OX=9606 GN=TLN1 PE=1 SV=3 6 3731.5 - 1.01E+06 - - - 1.8107 - 2.495 0.409 - 571.4 1 2 0 0.002 11 0 0 0 4.95E+07 3.26E+07 - - - 4.5346 0.9998 221125_WJC_METTL3_EV_vs_WT_F01.20078.20078.2 0.000434 13/20 K.IVFAAGNFWGR.T sp|P04181|OAT_HUMAN 1 1236.6404 0.29 7571 20078 2 1236.641641 619.3275 "Ornithine aminotransferase, mitochondrial OS=Homo sapiens OX=9606 GN=OAT PE=1 SV=1" 9.75 3731.9 - 794433 - - - 1.0221 - 2.247 0.461 - 564 1 2 0 0.0013 11 0 0 0 6.15E+06 2.15E+07 - - - 4.6357 0.9999 221125_WJC_METTL3_EV_vs_WT_F01.20079.20079.2 0.00547 18-Nov R.EYLLDMIPPR[166.11].S "sp|Q86YP4|P66A_HUMAN,sp|Q8WXI9|P66B_HUMAN,tr|A0A0U1RRM1|A0A0U1RRM1_HUMAN" 3 1255.651 2.25 7572 20079 2 1255.651192 628.8328 Transcriptional repressor p66-alpha OS=Homo sapiens OX=9606 GN=GATAD2A PE=1 SV=1 4.37 3732 - 720310 - - - 0.141 - 2.226 0.468 - 627.4 1 2 0 0.0002 10 0 0 0 1.63E+07 7.25E+06 - - - 4.7312 0.9998 221125_WJC_METTL3_EV_vs_WT_F01.20084.20084.2 2.60E-05 14/20 R.IPDQLVILDMK.H "sp|P49755|TMEDA_HUMAN,tr|G3V2K7|G3V2K7_HUMAN" 2 1283.7159 1.39 7575 20084 2 1283.714447 642.8652 Transmembrane emp24 domain-containing protein 10 OS=Homo sapiens OX=9606 GN=TMED10 PE=1 SV=2 4.21 3732.6 - 896153 - - - -1.1397 - 2.815 0.387 - 987.1 1 2 0 -0.0015 11 0 0 0 1.56E+08 1.12E+08 - - - 4.6987 0.9955 221125_WJC_METTL3_EV_vs_WT_F01.20085.20085.2 0.183 16-Aug R.FLYIWPNAR.L "sp|Q9HCC0|MCCB_HUMAN,tr|A0A804HJC1|A0A804HJC1_HUMAN,tr|A0A804HK37|A0A804HK37_HUMAN,tr|A0A804HJ24|A0A804HJ24_HUMAN,tr|A0A804HL02|A0A804HL02_HUMAN,tr|A0A804HKE8|A0A804HKE8_HUMAN,tr|A0A804HJ84|A0A804HJ84_HUMAN,tr|A0A804HLJ9|A0A804HLJ9_HUMAN,tr|A0A804HJL2|A0A804HJL2_HUMAN,tr|A0A804HKH3|A0A804HKH3_HUMAN,tr|A0A804HJ31|A0A804HJ31_HUMAN" 11 1178.6237 -1 7576 20085 2 1178.627485 590.3191 "Methylcrotonoyl-CoA carboxylase beta chain, mitochondrial OS=Homo sapiens OX=9606 GN=MCCC2 PE=1 SV=1" 8.75 3732.7 - 1.56E+06 - - - 3.2419 - 1.577 0.296 - 284.2 1 2 0 0.0038 9 0 0 0 0.00E+00 0.00E+00 - - - 2.5439 0.9987 221125_WJC_METTL3_EV_vs_WT_F01.20086.20086.2 0.0055 22-Sep K.SFSTALYGESDL.- "sp|O43707|ACTN4_HUMAN,sp|P12814|ACTN1_HUMAN,tr|A0A804HK61|A0A804HK61_HUMAN,tr|A0A804HJU8|A0A804HJU8_HUMAN,tr|A0A804HIN7|A0A804HIN7_HUMAN,tr|H9KV75|H9KV75_HUMAN,tr|A0A804HLF4|A0A804HLF4_HUMAN,tr|H0YJW3|H0YJW3_HUMAN,tr|A0A7I2V4Y4|A0A7I2V4Y4_HUMAN,tr|A0A804HII9|A0A804HII9_HUMAN,tr|A0A804HL31|A0A804HL31_HUMAN,tr|F5GXS2|F5GXS2_HUMAN,tr|A0A804HKE2|A0A804HKE2_HUMAN,tr|H7C144|H7C144_HUMAN" 14 1288.5823 - 7577 20086 2 1288.580858 645.2984 Alpha-actinin-4 OS=Homo sapiens OX=9606 GN=ACTN4 PE=1 SV=2 3.67 3732.8 - 771698 - - - -1.1291 - 1.668 0.262 - 225.6 1 2 0 -0.0015 12 0 0 0 - - - - - 2.3218 0.9998 221125_WJC_METTL3_EV_vs_WT_F01.20087.20087.2 9.45E-05 18-Aug K.NGFLLDGFPR.T "sp|P54819|KAD2_HUMAN,tr|A0A5F9ZHP2|A0A5F9ZHP2_HUMAN,tr|G3V213|G3V213_HUMAN,tr|F8VY04|F8VY04_HUMAN,tr|F8W1A4|F8W1A4_HUMAN,tr|A0A5K1VW67|A0A5K1VW67_HUMAN,tr|F8VZG5|F8VZG5_HUMAN" 7 1134.5822 1.21 7578 20087 2 1134.582423 568.2984 "Adenylate kinase 2, mitochondrial OS=Homo sapiens OX=9606 GN=AK2 PE=1 SV=2" 5.84 3733 - 755855 - - - 0.2018 - 1.756 0.478 - 206.6 1 2 0 0.0002 10 0 0 0 6.84E+06 5.63E+06 - - - 4.143 0.9799 221125_WJC_METTL3_EV_vs_WT_F01.20090.20090.2 1.34 12-May R.EFALWLK.D "sp|A6NHR9|SMHD1_HUMAN,tr|J3KTL8|J3KTL8_HUMAN" 2 905.5011 1.84 7581 20090 2 905.500391 453.7578 Structural maintenance of chromosomes flexible hinge domain-containing protein 1 OS=Homo sapiens OX=9606 GN=SMCHD1 PE=1 SV=2 6.1 3733.3 - 443184 - - - -0.7719 - 1.124 0.109 - 100 1 2 0 -0.0007 7 0 0 0 2.60E+06 1.41E+06 - - - 0.2162 0.9999 221125_WJC_METTL3_EV_vs_WT_F01.20104.20104.2 7.39E-05 24-Dec K.ILTFDQLALDSPK[136.11].G "sp|Q07020|RL18_HUMAN,tr|J3QQ67|J3QQ67_HUMAN,tr|F8VUA6|F8VUA6_HUMAN,tr|G3V203|G3V203_HUMAN,tr|H0YHA7|H0YHA7_HUMAN" 5 1467.8064 1.01 7593 20104 2 1467.805202 734.9105 60S ribosomal protein L18 OS=Homo sapiens OX=9606 GN=RPL18 PE=1 SV=2 4.21 3735 - 1.59E+06 - - - -0.8475 - 2.414 0.487 - 447.5 1 2 0 -0.0012 13 0 0 0 1.44E+08 1.43E+08 - - - 4.8994 0.9997 221125_WJC_METTL3_EV_vs_WT_F01.20106.20106.2 0.000919 16-Aug R.YLDVSILGK[136.11].F sp|Q86U44|MTA70_HUMAN 1 1014.5841 0.43 7595 20106 2 1014.584976 508.2993 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 5.83 3735.2 - 822267 - - - 0.8654 - 1.696 0.455 - 155.3 1 2 0 0.0009 9 0 0 0 3.04E+06 7.05E+06 - - - 3.9297 0.8658 221125_WJC_METTL3_EV_vs_WT_F01.20109.20109.2 0.0085 13/24 R.ALDPAAAAYLFQR[166.11].Q "sp|O75376|NCOR1_HUMAN,tr|E7EVK1|E7EVK1_HUMAN" 2 1415.7437 -1 7598 20109 2 1415.733289 708.8791 Nuclear receptor corepressor 1 OS=Homo sapiens OX=9606 GN=NCOR1 PE=1 SV=2 5.88 3735.5 - 684758 - - - -7.3325 - 2.094 0.136 - 376.5 1 2 0 -0.0104 13 0 0 0 0.00E+00 0.00E+00 - - - 1.9391 0.9951 221125_WJC_METTL3_EV_vs_WT_F01.20110.20110.2 0.166 14-Jul R.DLLIDEWK[136.11].S "sp|Q16539|MK14_HUMAN,tr|B4E0K5|B4E0K5_HUMAN" 2 1038.5477 0.66 7599 20110 2 1038.548741 520.2811 Mitogen-activated protein kinase 14 OS=Homo sapiens OX=9606 GN=MAPK14 PE=1 SV=3 4.03 3735.6 - 655122 - - - 0.9908 - 1.361 0.182 - 120.5 1 2 0 0.001 8 0 0 0 2.89E+06 4.38E+06 - - - 1.3145 0.9997 221125_WJC_METTL3_EV_vs_WT_F01.20111.20111.2 1.34E-05 18-Dec R.TLVEDLFADK.H "sp|O75643|U520_HUMAN,tr|A0A494C1A5|A0A494C1A5_HUMAN" 2 1149.5918 1.71 7600 20111 2 1149.594398 575.8032 U5 small nuclear ribonucleoprotein 200 kDa helicase OS=Homo sapiens OX=9606 GN=SNRNP200 PE=1 SV=2 4.03 3735.8 - 589270 - - - 2.2991 - 2.129 0.518 - 371.1 1 2 0 0.0026 10 0 0 0 5.82E+07 3.40E+07 - - - 4.9754 0.9997 221125_WJC_METTL3_EV_vs_WT_F01.20113.20113.2 6.95E-05 18-Nov R.TLVEDLFADK[136.11].H "sp|O75643|U520_HUMAN,tr|A0A494C1A5|A0A494C1A5_HUMAN" 2 1157.606 1.71 7602 20113 2 1157.608194 579.8103 U5 small nuclear ribonucleoprotein 200 kDa helicase OS=Homo sapiens OX=9606 GN=SNRNP200 PE=1 SV=2 4.03 3736 - 432714 - - - 1.9342 - 2.047 0.474 - 285.5 1 2 0 0.0022 10 0 0 0 5.82E+07 3.40E+07 - - - 4.5409 0.9998 221125_WJC_METTL3_EV_vs_WT_F01.20115.20115.2 0.00013 22-Oct K.FLQDTIEEMALK[136.11].N sp|O95202|LETM1_HUMAN 1 1444.7363 1.06 7604 20115 2 1444.735926 723.3754 Mitochondrial proton\calcium exchanger protein OS=Homo sapiens OX=9606 GN=LETM1 PE=1 SV=1 4.14 3736.3 - 357037 - - - -0.2713 - 1.878 0.494 - 242.2 1 2 0 -0.0004 12 0 0 0 7.54E+06 7.10E+06 - - - 4.3477 0.9992 221125_WJC_METTL3_EV_vs_WT_F01.20116.20116.2 1.16E-05 24-Nov R.LAALPNVYEVISK[136.11].S "sp|P33992|MCM5_HUMAN,tr|B1AHB1|B1AHB1_HUMAN" 2 1423.8166 0.48 7605 20116 2 1423.820554 712.9156 DNA replication licensing factor MCM5 OS=Homo sapiens OX=9606 GN=MCM5 PE=1 SV=5 6 3736.4 - 275938 - - - 2.7651 - 2.045 0.422 - 310.3 1 2 0 0.0039 13 0 0 0 2.52E+07 5.22E+07 - - - 3.9927 0.9996 221125_WJC_METTL3_EV_vs_WT_F01.20117.20117.2 8.64E-09 15/26 K.GLIGNLYLNDSPLK[136.11].N sp|Q8IW92|GLBL2_HUMAN 1 1523.8439 1.3 7606 20117 2 1523.839168 762.9292 Beta-galactosidase-1-like protein 2 OS=Homo sapiens OX=9606 GN=GLB1L2 PE=1 SV=1 5.83 3736.5 - 255193 - - - -3.1014 - 2.892 0.519 - 1019.2 1 2 0 -0.0047 14 0 0 0 6.38E+06 4.92E+06 - - - 5.5378 0.9999 221125_WJC_METTL3_EV_vs_WT_F01.20118.20118.2 1.66E-06 28-Nov K.ELVGPPLAETVFTPK.T sp|P49792|RBP2_HUMAN 1 1596.8763 0.9 7607 20118 2 1596.876925 799.4454 E3 SUMO-protein ligase RanBP2 OS=Homo sapiens OX=9606 GN=RANBP2 PE=1 SV=2 4.53 3736.7 - 253570 - - - 0.3851 - 2.21 0.538 - 288.2 1 2 0 0.0006 15 0 0 0 2.32E+07 2.58E+07 - - - 4.9641 0.9988 221125_WJC_METTL3_EV_vs_WT_F01.20119.20119.2 0.00364 18-Aug R.VLQDFYLELR[166.11].K "sp|Q9UJA3|MCM8_HUMAN,tr|A0A494C100|A0A494C100_HUMAN" 2 1304.7004 0.58 7608 20119 2 1304.703987 653.3575 DNA helicase MCM8 OS=Homo sapiens OX=9606 GN=MCM8 PE=1 SV=2 4.37 3736.8 - 233797 - - - 2.7432 - 1.936 0.353 - 311.6 1 2 0 0.0036 10 0 0 0 8.11E+05 1.39E+06 - - - 3.4911 0.9998 221125_WJC_METTL3_EV_vs_WT_F01.20122.20122.2 0.00407 20-Dec R.AFITNIPFDVK.W "sp|P52272|HNRPM_HUMAN,tr|M0R019|M0R019_HUMAN,tr|M0R0Y6|M0R0Y6_HUMAN,tr|M0R0N3|M0R0N3_HUMAN,tr|A0A087X0X3|A0A087X0X3_HUMAN,tr|M0QYQ7|M0QYQ7_HUMAN,tr|M0R2T0|M0R2T0_HUMAN" 7 1263.6863 1.73 7610 20122 2 1263.68696 632.8504 Heterogeneous nuclear ribonucleoprotein M OS=Homo sapiens OX=9606 GN=HNRNPM PE=1 SV=3 5.88 3737.2 - 2.24E+07 - - - 0.5033 - 2.156 0.445 - 566.1 1 2 0 0.0006 11 0 0 0 9.94E+08 5.73E+08 - - - 4.4059 0.9998 221125_WJC_METTL3_EV_vs_WT_F01.20124.20124.2 0.00099 18-Dec K.ILLAELEQLK.G "sp|P08670|VIME_HUMAN,tr|B0YJC4|B0YJC4_HUMAN,tr|A0A1B0GTT5|A0A1B0GTT5_HUMAN" 3 1168.7067 1.9 7611 20124 2 1168.707366 585.3606 Vimentin OS=Homo sapiens OX=9606 GN=VIM PE=1 SV=4 4.53 3737.4 - 1.31E+07 - - - 0.5485 - 2.37 0.403 - 410 1 2 0 0.0006 10 0 0 0 9.54E+09 5.02E+09 - - - 4.4259 0.9997 221125_WJC_METTL3_EV_vs_WT_F01.20125.20125.2 0.0106 18-Oct K.ILLAELEQLK[136.11].G "sp|P08670|VIME_HUMAN,tr|B0YJC4|B0YJC4_HUMAN,tr|A0A1B0GTT5|A0A1B0GTT5_HUMAN" 3 1176.7209 1.9 7612 20125 2 1176.721615 589.3677 Vimentin OS=Homo sapiens OX=9606 GN=VIM PE=1 SV=4 4.53 3737.5 - 9.31E+06 - - - 0.5864 - 2.194 0.335 - 256.6 1 2 0 0.0007 10 0 0 0 9.54E+09 5.02E+09 - - - 3.7083 0.9997 221125_WJC_METTL3_EV_vs_WT_F01.20126.20126.2 0.000464 14-Aug R.DWVLNEFR.S "sp|Q92841|DDX17_HUMAN,tr|A0A0U1RQJ0|A0A0U1RQJ0_HUMAN,tr|A0A5H1ZRQ2|A0A5H1ZRQ2_HUMAN,tr|A0A1X7SBZ2|A0A1X7SBZ2_HUMAN" 4 1077.5243 1.14 7613 20126 2 1077.525485 539.7694 Probable ATP-dependent RNA helicase DDX17 OS=Homo sapiens OX=9606 GN=DDX17 PE=1 SV=2 4.37 3737.5 - 1.23E+06 - - - 1.0589 - 1.885 0.418 - 373.8 1 2 0 0.0011 8 0 0 0 9.12E+07 7.97E+07 - - - 4.0399 0.9971 221125_WJC_METTL3_EV_vs_WT_F01.20129.20129.2 0.00407 12-Jul K.VFFDLMR.E "sp|P11234|RALB_HUMAN,sp|P11233|RALA_HUMAN" 2 926.4684 0.8 7616 20129 2 926.470703 464.2415 Ras-related protein Ral-B OS=Homo sapiens OX=9606 GN=RALB PE=1 SV=1 5.81 3737.9 - 796589 - - - 2.4761 - 1.392 0.32 - 206.4 1 2 0 0.0023 7 0 0 0 1.91E+07 2.38E+07 - - - 2.4518 1 221125_WJC_METTL3_EV_vs_WT_F01.20133.20133.2 1.70E-07 15/26 K.GLIGNLYLNDSPLK.N sp|Q8IW92|GLBL2_HUMAN 1 1515.8297 1.3 7620 20133 2 1515.830309 758.9221 Beta-galactosidase-1-like protein 2 OS=Homo sapiens OX=9606 GN=GLB1L2 PE=1 SV=1 5.83 3738.4 - 553636 - - - 0.4057 - 2.805 0.594 - 946.6 1 2 0 0.0006 14 0 0 0 6.38E+06 4.92E+06 - - - 6.0163 0.9998 221125_WJC_METTL3_EV_vs_WT_F01.20134.20134.2 3.33E-06 28-Dec K.ELVGPPLAETVFTPK[136.11].T sp|P49792|RBP2_HUMAN 1 1604.8905 0.9 7621 20134 2 1604.893717 803.4525 E3 SUMO-protein ligase RanBP2 OS=Homo sapiens OX=9606 GN=RANBP2 PE=1 SV=2 4.53 3738.5 - 472949 - - - 1.9983 - 2.526 0.538 - 362 1 2 0 0.0032 15 0 0 0 2.32E+07 2.58E+07 - - - 5.2918 0.9969 221125_WJC_METTL3_EV_vs_WT_F01.20137.20137.2 0.179 12-Aug K.LWDLYLR[166.11].T "sp|Q86U86|PB1_HUMAN,tr|H0Y5B5|H0Y5B5_HUMAN,tr|E7EVG2|E7EVG2_HUMAN,tr|C9JPI5|C9JPI5_HUMAN,tr|C9JQF1|C9JQF1_HUMAN" 5 987.5417 1.49 7624 20137 2 987.543549 494.7781 Protein polybromo-1 OS=Homo sapiens OX=9606 GN=PBRM1 PE=1 SV=1 5.84 3738.9 - 414557 - - - 1.85 - 1.736 0.17 - 246.6 1 2 0 0.0018 7 0 0 0 9.42E+06 6.34E+06 - - - 2.0438 0.9992 221125_WJC_METTL3_EV_vs_WT_F01.20139.20139.2 0.000368 24-Dec R.ALDPAAAAYLFQR.Q "sp|O75376|NCOR1_HUMAN,tr|E7EVK1|E7EVK1_HUMAN" 2 1405.7354 -1 7626 20139 2 1405.739339 703.875 Nuclear receptor corepressor 1 OS=Homo sapiens OX=9606 GN=NCOR1 PE=1 SV=2 5.88 3739.1 - 365967 - - - 2.8021 - 2.108 0.432 - 400.3 1 2 0 0.0039 13 0 0 0 0.00E+00 0.00E+00 - - - 4.1445 0.9998 221125_WJC_METTL3_EV_vs_WT_F01.20140.20140.2 2.92E-05 13/22 R.FGPLTPELMVPR[166.11].L "sp|P40937|RFC5_HUMAN,tr|F5H5S0|F5H5S0_HUMAN" 2 1365.7354 5.51 7627 20140 2 1365.737431 683.875 Replication factor C subunit 5 OS=Homo sapiens OX=9606 GN=RFC5 PE=1 SV=1 6 3739.3 - 212029 - - - 1.4776 - 2.453 0.498 - 479 1 2 0 0.002 12 0 0 0 9.16E+07 1.66E+07 - - - 5.0796 0.9954 221125_WJC_METTL3_EV_vs_WT_F01.20141.20141.3 0.299 Jul-36 R.EYLLDMIPPR.S "sp|Q86YP4|P66A_HUMAN,sp|Q8WXI9|P66B_HUMAN,tr|A0A0U1RRM1|A0A0U1RRM1_HUMAN" 3 1245.6427 3.6 7628 20141 3 1245.643967 416.2215 Transcriptional repressor p66-alpha OS=Homo sapiens OX=9606 GN=GATAD2A PE=1 SV=1 4.37 3739.4 - 189739 - - - 0.981 - 1.487 0.238 - 91.2 1 2 0 0.0012 10 0 0 0 3.45E+06 9.60E+05 - - - 2.3518 0.9968 221125_WJC_METTL3_EV_vs_WT_F01.20142.20142.3 0.00115 Nov-36 K.ILLAELEQLK[136.11].G "sp|P08670|VIME_HUMAN,tr|B0YJC4|B0YJC4_HUMAN,tr|A0A1B0GTT5|A0A1B0GTT5_HUMAN" 3 1176.7209 2 7629 20142 3 1176.71406 393.2476 Vimentin OS=Homo sapiens OX=9606 GN=VIM PE=1 SV=4 4.53 3739.5 - 159542 - - - -5.834 - 2.264 0.374 - 142.8 1 2 0 -0.0069 10 0 0 0 1.40E+08 7.01E+07 - - - 5.0942 0.9995 221125_WJC_METTL3_EV_vs_WT_F01.20147.20147.2 1.67E-05 14-Aug R.DWVLNEFR[166.11].S "sp|Q92841|DDX17_HUMAN,tr|A0A0U1RQJ0|A0A0U1RQJ0_HUMAN,tr|A0A5H1ZRQ2|A0A5H1ZRQ2_HUMAN,tr|A0A1X7SBZ2|A0A1X7SBZ2_HUMAN" 4 1087.5326 1.14 7632 20147 2 1087.531922 544.7736 Probable ATP-dependent RNA helicase DDX17 OS=Homo sapiens OX=9606 GN=DDX17 PE=1 SV=2 4.37 3740.1 - 6.42E+06 - - - -0.6363 - 1.838 0.308 - 382 1 2 0 -0.0007 8 0 0 0 9.12E+07 7.97E+07 - - - 3.1514 0.9993 221125_WJC_METTL3_EV_vs_WT_F01.20149.20149.2 0.0105 16-Aug R.DSVVLSLLK[136.11].Q sp|O43264|ZW10_HUMAN 1 980.5997 0.85 7634 20149 2 980.601307 491.3072 Centromere\kinetochore protein zw10 homolog OS=Homo sapiens OX=9606 GN=ZW10 PE=1 SV=3 5.84 3740.3 - 1.53E+06 - - - 1.5898 - 1.879 0.331 - 202.6 1 2 0 0.0016 9 0 0 0 9.69E+06 1.14E+07 - - - 3.31 0.9994 221125_WJC_METTL3_EV_vs_WT_F01.20151.20151.2 0.00425 24-Oct R.LAALPNVYEVISK.S "sp|P33992|MCM5_HUMAN,tr|B1AHB1|B1AHB1_HUMAN" 2 1415.8024 0.48 7636 20151 2 1415.802434 708.9085 DNA replication licensing factor MCM5 OS=Homo sapiens OX=9606 GN=MCM5 PE=1 SV=5 6 3740.5 - 883239 - - - 0.012 - 1.866 0.305 - 247.8 1 2 0 0 13 0 0 0 2.52E+07 5.22E+07 - - - 2.8947 0.9998 221125_WJC_METTL3_EV_vs_WT_F01.20153.20153.2 6.31E-05 28-Nov K.VLSVPESTPFTAVLK.F "sp|P61960|UFM1_HUMAN,tr|H0Y614|H0Y614_HUMAN" 2 1586.892 2.06 7638 20153 2 1586.892603 794.4533 Ubiquitin-fold modifier 1 OS=Homo sapiens OX=9606 GN=UFM1 PE=1 SV=1 5.97 3740.7 - 590570 - - - 0.4052 - 1.947 0.438 - 246.4 1 2 0 0.0006 15 0 0 0 1.01E+07 4.91E+06 - - - 3.914 0.9983 221125_WJC_METTL3_EV_vs_WT_F01.20156.20156.2 0.00203 26-Sep R.LFNGTEPIVLDSLK[136.11].Q "sp|Q96SI1|KCD15_HUMAN,tr|K7EN63|K7EN63_HUMAN,tr|K7EM48|K7EM48_HUMAN" 3 1552.8592 -1 7641 20156 2 1552.854397 777.4369 BTB\POZ domain-containing protein KCTD15 OS=Homo sapiens OX=9606 GN=KCTD15 PE=1 SV=1 4.37 3741.1 - 335207 - - - -3.0994 - 1.767 0.396 - 79.2 1 2 0 -0.0048 14 0 0 0 0.00E+00 0.00E+00 - - - 3.3929 0.9997 221125_WJC_METTL3_EV_vs_WT_F01.20157.20157.2 0.184 18-Dec R.VDILDPALLR.S "sp|P17980|PRS6A_HUMAN,tr|R4GNH3|R4GNH3_HUMAN,tr|E9PKD5|E9PKD5_HUMAN,tr|E9PM69|E9PM69_HUMAN" 4 1123.6601 0.73 7642 20157 2 1123.659144 562.8373 26S proteasome regulatory subunit 6A OS=Homo sapiens OX=9606 GN=PSMC3 PE=1 SV=3 4.21 3741.3 - 317800 - - - -0.8597 - 2.269 0.33 - 376.1 1 2 0 -0.001 10 0 0 0 9.72E+07 1.34E+08 - - - 3.7651 0.8185 221125_WJC_METTL3_EV_vs_WT_F01.20158.20158.2 0.68 26-May M.EPGGDHR[166.11]SR[166.11]SSGGR[166.11].G "sp|C9JLR9|ZFTA_HUMAN,tr|A0A087WZS6|A0A087WZS6_HUMAN" 2 1483.7019 0.02 7643 20158 2 1483.703659 742.8582 Zinc finger translocation-associated protein OS=Homo sapiens OX=9606 GN=ZFTA PE=1 SV=1 9.61 3741.4 - 234971 - - - 1.2125 - 1.048 0.172 - 58 1 2 2 0.0018 14 0 0 0 6.90E+04 4.57E+06 - - - 0.4285 0.8548 221125_WJC_METTL3_EV_vs_WT_F01.20162.20162.2 0.0119 16-Jul K.GPLQSVQVF.G "sp|P62249|RS16_HUMAN,tr|M0R210|M0R210_HUMAN,tr|M0R3H0|M0R3H0_HUMAN,tr|Q6IPX4|Q6IPX4_HUMAN" 4 973.5233 - 7645 20162 2 973.521619 487.7689 40S ribosomal protein S16 OS=Homo sapiens OX=9606 GN=RPS16 PE=1 SV=2 5.52 3741.9 - 2.93E+06 - - - -1.7082 - 1.349 0.28 - 139.4 1 1 0 -0.0017 9 0 0 0 - - - - - 1.9746 0.9991 221125_WJC_METTL3_EV_vs_WT_F01.20163.20163.2 0.918 18-Sep R.VDILDPALLR[166.11].S "sp|P17980|PRS6A_HUMAN,tr|R4GNH3|R4GNH3_HUMAN,tr|E9PKD5|E9PKD5_HUMAN,tr|E9PM69|E9PM69_HUMAN" 4 1133.6684 0.73 7646 20163 2 1133.668364 567.8415 26S proteasome regulatory subunit 6A OS=Homo sapiens OX=9606 GN=PSMC3 PE=1 SV=3 4.21 3742 - 2.07E+06 - - - -0.0141 - 2.015 0.202 - 238.2 1 2 0 0 10 0 0 0 9.72E+07 1.34E+08 - - - 2.4886 0.9333 221125_WJC_METTL3_EV_vs_WT_F01.20167.20167.2 0.0143 15/26 K.LLAESVTEVEIFGK.A "sp|Q14204|DYHC1_HUMAN,tr|A0A7P0T8N2|A0A7P0T8N2_HUMAN,tr|A0A7P0T9C4|A0A7P0T9C4_HUMAN,tr|A0A7P0TBJ7|A0A7P0TBJ7_HUMAN,tr|A0A804HHY6|A0A804HHY6_HUMAN,tr|A0A7P0T9K2|A0A7P0T9K2_HUMAN,tr|A0A7P0TB64|A0A7P0TB64_HUMAN,tr|A0A2R8Y706|A0A2R8Y706_HUMAN,tr|A0A7P0T916|A0A7P0T916_HUMAN,tr|A0A7P0TB75|A0A7P0TB75_HUMAN,tr|A0A7P0T8W5|A0A7P0T8W5_HUMAN,tr|A0A7P0T9S3|A0A7P0T9S3_HUMAN,tr|A0A7P0TAF3|A0A7P0TAF3_HUMAN,tr|A0A7P0T9F1|A0A7P0T9F1_HUMAN,tr|A0A7P0TAW9|A0A7P0TAW9_HUMAN,tr|A0A2R8YGC7|A0A2R8YGC7_HUMAN,tr|A0A7P0TA13|A0A7P0TA13_HUMAN,tr|A0A7P0T934|A0A7P0T934_HUMAN,tr|A0A7P0TAV5|A0A7P0TAV5_HUMAN,tr|A0A7P0T7V5|A0A7P0T7V5_HUMAN,tr|A0A7P0T9R4|A0A7P0T9R4_HUMAN,tr|A0A2R8Y5T0|A0A2R8Y5T0_HUMAN,tr|A0A7P0T990|A0A7P0T990_HUMAN,tr|A0A7P0T942|A0A7P0T942_HUMAN,tr|A0A2R8YFZ7|A0A2R8YFZ7_HUMAN,tr|A0A7P0T825|A0A7P0T825_HUMAN,tr|A0A2R8Y6H2|A0A2R8Y6H2_HUMAN,tr|A0A7P0TAM4|A0A7P0TAM4_HUMAN" 28 1533.829 2.31 7650 20167 2 1533.819954 767.9218 Cytoplasmic dynein 1 heavy chain 1 OS=Homo sapiens OX=9606 GN=DYNC1H1 PE=1 SV=5 4.25 3742.5 - 551086 - - - -5.9146 - 2.037 0.134 - 249 1 2 0 -0.0091 14 0 0 0 1.26E+07 5.44E+06 - - - 1.8133 0.9994 221125_WJC_METTL3_EV_vs_WT_F01.20168.20168.2 0.00187 16-Sep K.QVDLIDLVR.W sp|Q9UKN8|TF3C4_HUMAN 1 1069.6132 0.74 7651 20168 2 1069.614052 535.8139 General transcription factor 3C polypeptide 4 OS=Homo sapiens OX=9606 GN=GTF3C4 PE=1 SV=2 4.21 3742.6 - 544323 - - - 0.8349 - 1.633 0.354 - 296.5 1 2 0 0.0009 9 0 0 0 1.26E+07 1.70E+07 - - - 3.0742 1 221125_WJC_METTL3_EV_vs_WT_F01.20178.20178.2 1.27E-07 15/24 R.WVNLPEESLLRPA.Y sp|O43505|B4GA1_HUMAN 1 1522.8144 2.61 7659 20178 2 1522.810703 762.4145 "Beta-1,4-glucuronyltransferase 1 OS=Homo sapiens OX=9606 GN=B4GAT1 PE=1 SV=1" 4.53 3743.9 - 1.06E+06 - - - -2.4133 - 2.819 0.614 - 619.6 1 1 0 -0.0037 13 0 0 0 1.45E+07 5.53E+06 - - - 6.2348 0.8433 221125_WJC_METTL3_EV_vs_WT_F01.20179.20179.2 0.981 16-Dec L.LLAELEQLK.G "sp|P08670|VIME_HUMAN,tr|B0YJC4|B0YJC4_HUMAN,tr|A0A1B0GTT5|A0A1B0GTT5_HUMAN" 3 1055.6227 1.96 7660 20179 2 1055.618355 528.8186 Vimentin OS=Homo sapiens OX=9606 GN=VIM PE=1 SV=4 4.53 3744 - 1.05E+06 - - - -4.0791 - 2.319 0.278 - 361.5 1 1 0 -0.0043 9 0 0 0 1.20E+07 6.13E+06 - - - 3.5264 0.9998 221125_WJC_METTL3_EV_vs_WT_F01.20191.20191.2 1.28E-06 13/24 K.ILTFDQLALDSPK.G "sp|Q07020|RL18_HUMAN,tr|J3QQ67|J3QQ67_HUMAN,tr|F8VUA6|F8VUA6_HUMAN,tr|G3V203|G3V203_HUMAN,tr|H0YHA7|H0YHA7_HUMAN" 5 1459.7922 1.01 7669 20191 2 1459.788903 730.9034 60S ribosomal protein L18 OS=Homo sapiens OX=9606 GN=RPL18 PE=1 SV=2 4.21 3745.5 - 2.76E+06 - - - -2.2901 - 2.7 0.548 - 673.9 1 2 0 -0.0033 13 0 0 0 1.44E+08 1.43E+08 - - - 5.6367 0.9996 221125_WJC_METTL3_EV_vs_WT_F01.20195.20195.2 2.14E-06 22-Dec R.GNSIIMLEALER.V "sp|P62308|RUXG_HUMAN,sp|A8MWD9|RUXGL_HUMAN,tr|Q49AN9|Q49AN9_HUMAN,tr|F5H013|F5H013_HUMAN" 4 1344.7071 0.86 7672 20195 2 1344.703544 673.3608 Small nuclear ribonucleoprotein G OS=Homo sapiens OX=9606 GN=SNRPG PE=1 SV=1 4.53 3746 - 1.94E+06 - - - -2.6712 - 2.591 0.449 - 624.8 1 2 0 -0.0036 12 0 0 0 2.23E+07 2.59E+07 - - - 4.8612 0.9996 221125_WJC_METTL3_EV_vs_WT_F01.20196.20196.2 0.0018 14-Oct R.VLGLVLLR[166.11].G "sp|P63162|RSMN_HUMAN,sp|Q92611|EDEM1_HUMAN,sp|P14678|RSMB_HUMAN,tr|J3QLE5|J3QLE5_HUMAN" 4 891.6145 0.71 7673 20196 2 891.61351 446.8145 Small nuclear ribonucleoprotein-associated protein N OS=Homo sapiens OX=9606 GN=SNRPN PE=1 SV=1 9.72 3746.1 - 1.69E+06 - - - -1.1025 - 2.016 0.319 - 409.9 1 2 0 -0.001 8 0 0 0 2.51E+07 3.52E+07 - - - 3.5114 0.9993 221125_WJC_METTL3_EV_vs_WT_F01.20198.20198.2 0.000601 22-Nov R.NVYPEEMIVALR[166.11].E sp|Q5VT52|RPRD2_HUMAN 1 1442.7467 4.19 7675 20198 2 1442.742362 722.3806 Regulation of nuclear pre-mRNA domain-containing protein 2 OS=Homo sapiens OX=9606 GN=RPRD2 PE=1 SV=1 4.53 3746.4 - 673718 - - - -3.0109 - 2.072 0.467 - 421.5 1 2 0 -0.0043 12 0 0 0 3.31E+07 7.89E+06 - - - 4.4057 0.9984 221125_WJC_METTL3_EV_vs_WT_F01.20200.20200.3 0.0116 Aug-36 K.ILLAELEQLK.G "sp|P08670|VIME_HUMAN,tr|B0YJC4|B0YJC4_HUMAN,tr|A0A1B0GTT5|A0A1B0GTT5_HUMAN" 3 1168.7067 2 7676 20200 3 1168.704139 390.5762 Vimentin OS=Homo sapiens OX=9606 GN=VIM PE=1 SV=4 4.53 3746.6 - 8.02E+06 - - - -2.2127 - 1.778 0.296 - 84.1 1 2 0 -0.0026 10 0 0 0 1.40E+08 7.01E+07 - - - 3.5201 0.9978 221125_WJC_METTL3_EV_vs_WT_F01.20204.20204.2 0.00536 18-Sep K.DFLLQQTMLR[166.11].V sp|Q04760|LGUL_HUMAN 1 1273.6728 0.8 7679 20204 2 1273.667137 637.8437 Lactoylglutathione lyase OS=Homo sapiens OX=9606 GN=GLO1 PE=1 SV=4 5.84 3747 - 1.81E+06 - - - -4.4564 - 2.008 0.449 - 335.9 1 2 0 -0.0057 10 0 0 0 1.54E+07 1.92E+07 - - - 4.3015 0.9993 221125_WJC_METTL3_EV_vs_WT_F01.20206.20206.2 0.167 14-Oct R.VLGLVLLR.G "sp|P63162|RSMN_HUMAN,sp|Q92611|EDEM1_HUMAN,sp|P14678|RSMB_HUMAN,tr|J3QLE5|J3QLE5_HUMAN" 4 881.6062 0.71 7681 20206 2 881.604391 441.8104 Small nuclear ribonucleoprotein-associated protein N OS=Homo sapiens OX=9606 GN=SNRPN PE=1 SV=1 9.72 3747.2 - 1.63E+06 - - - -2.078 - 2.063 0.314 - 349.3 1 2 0 -0.0018 8 0 0 0 2.51E+07 3.52E+07 - - - 3.5437 0.9996 221125_WJC_METTL3_EV_vs_WT_F01.20211.20211.2 0.0158 14-Oct K.QELLELFK.E "sp|Q9H089|LSG1_HUMAN,tr|H7C2X7|H7C2X7_HUMAN" 2 1018.5699 0.91 7686 20211 2 1018.569161 510.2922 Large subunit GTPase 1 homolog OS=Homo sapiens OX=9606 GN=LSG1 PE=1 SV=2 4.53 3747.7 - 1.18E+06 - - - -0.7236 - 1.788 0.356 - 339.7 1 2 0 -0.0007 8 0 0 0 2.29E+07 2.53E+07 - - - 3.4227 0.9997 221125_WJC_METTL3_EV_vs_WT_F01.20222.20222.2 0.0027 16-Sep K.ELALSALLK[136.11].F "sp|Q9BVI4|NOC4L_HUMAN,tr|F5H303|F5H303_HUMAN" 2 964.6048 0.89 7695 20222 2 964.604995 483.3097 Nucleolar complex protein 4 homolog OS=Homo sapiens OX=9606 GN=NOC4L PE=1 SV=1 6.1 3748.9 - 875770 - - - 0.1679 - 1.818 0.411 - 251.7 1 2 0 0.0002 9 0 0 0 1.43E+07 1.61E+07 - - - 3.8059 0.9845 221125_WJC_METTL3_EV_vs_WT_F01.20224.20224.2 0.00645 24-Sep L.SLGIETLGGVFTK.L "sp|P38646|GRP75_HUMAN,tr|A0A7I2V2S7|A0A7I2V2S7_HUMAN,tr|A0A7I2V2G2|A0A7I2V2G2_HUMAN,tr|A0A7I2YQB2|A0A7I2YQB2_HUMAN,tr|D6RCD7|D6RCD7_HUMAN" 5 1320.7289 0.46 7697 20224 2 1320.730495 661.3717 "Stress-70 protein, mitochondrial OS=Homo sapiens OX=9606 GN=HSPA9 PE=1 SV=2" 5.72 3749.1 - 739443 - - - 1.1948 - 2.216 0.426 - 183.6 1 1 0 0.0016 13 0 0 0 8.54E+06 1.85E+07 - - - 4.2291 0.9999 221125_WJC_METTL3_EV_vs_WT_F01.20225.20225.2 1.41E-06 22-Oct R.LLTFMGMAVENK[136.11].E "sp|Q7L2H7|EIF3M_HUMAN,tr|H0YCQ8|H0YCQ8_HUMAN" 2 1360.6974 0.95 7698 20225 2 1360.696745 681.356 Eukaryotic translation initiation factor 3 subunit M OS=Homo sapiens OX=9606 GN=EIF3M PE=1 SV=1 6 3749.3 - 733055 - - - -0.5034 - 2.223 0.546 - 230.5 1 2 0 -0.0007 12 0 0 0 8.17E+06 8.60E+06 - - - 5.1755 0.9984 221125_WJC_METTL3_EV_vs_WT_F01.20226.20226.2 0.0165 16-Aug K.ELALSALLK.F "sp|Q9BVI4|NOC4L_HUMAN,tr|F5H303|F5H303_HUMAN" 2 956.5906 0.89 7699 20226 2 956.588937 479.3026 Nucleolar complex protein 4 homolog OS=Homo sapiens OX=9606 GN=NOC4L PE=1 SV=1 6.1 3749.4 - 692495 - - - -1.773 - 1.582 0.291 - 170.8 1 2 0 -0.0017 9 0 0 0 1.43E+07 1.61E+07 - - - 2.5168 0.9944 221125_WJC_METTL3_EV_vs_WT_F01.20230.20230.2 0.000141 22-Oct R.GYELLFQPEVVR.L "sp|O60716|CTND1_HUMAN,tr|A0A669KB62|A0A669KB62_HUMAN,tr|A0A804HJM1|A0A804HJM1_HUMAN,tr|A0A804HK15|A0A804HK15_HUMAN,tr|A0A669KB05|A0A669KB05_HUMAN,tr|C9JZR2|C9JZR2_HUMAN,tr|H0YC95|H0YC95_HUMAN,tr|A0A804HIL4|A0A804HIL4_HUMAN" 8 1448.7664 0.26 7703 20230 2 1448.766968 725.3905 Catenin delta-1 OS=Homo sapiens OX=9606 GN=CTNND1 PE=1 SV=1 4.53 3749.9 - 531198 - - - 0.4155 - 2.111 0.026 - 360.2 2 2 0 0.0006 12 0 0 0 5.97E+06 2.27E+07 - - - 1.0643 0.9238 221125_WJC_METTL3_EV_vs_WT_F01.20235.20235.2 0.0409 14-Aug R.VDEIIWVK[136.11].T sp|Q86U44|MTA70_HUMAN 1 1008.5735 0.05 7706 20235 2 1008.569561 505.294 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 4.37 3750.6 - 1.14E+06 - - - -3.9382 - 1.469 0.065 - 140.1 1 2 0 -0.004 8 0 0 0 4.79E+05 9.28E+06 - - - 0.6797 0.9992 221125_WJC_METTL3_EV_vs_WT_F01.20244.20244.2 0.000753 18-Oct K.LVFPQDLLEK[136.11].G "sp|Q8TCT9|HM13_HUMAN,tr|A0A3B3IT72|A0A3B3IT72_HUMAN,tr|A0A0S2Z6F0|A0A0S2Z6F0_HUMAN,tr|A0A3B3IUB5|A0A3B3IUB5_HUMAN,tr|A0A075B6F6|A0A075B6F6_HUMAN" 5 1208.6896 1.25 7715 20244 2 1208.69169 605.3521 Minor histocompatibility antigen H13 OS=Homo sapiens OX=9606 GN=HM13 PE=1 SV=1 4.37 3751.7 - 600450 - - - 1.7085 - 1.739 0.35 - 298.9 1 2 0 0.0021 10 0 0 0 1.31E+07 1.05E+07 - - - 3.1699 0.9571 221125_WJC_METTL3_EV_vs_WT_F01.20245.20245.2 0.493 12-Jul R.LNIPVLQ.D sp|Q86U44|MTA70_HUMAN 1 795.4854 - 7716 20245 2 795.485893 398.75 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 5.52 3751.9 - 534169 - - - 0.5695 - 1.603 0.298 - 205.8 1 1 0 0.0005 7 0 0 0 - - - - - 2.7371 0.9999 221125_WJC_METTL3_EV_vs_WT_F01.20249.20249.2 0.000479 20-Dec R.LEYC[160.03]EALAMLR[166.11].E "sp|P14868|SYDC_HUMAN,tr|H7BZ35|H7BZ35_HUMAN" 2 1377.666 0.86 7720 20249 2 1377.665243 689.8403 "Aspartate--tRNA ligase, cytoplasmic OS=Homo sapiens OX=9606 GN=DARS1 PE=1 SV=2" 4.53 3752.3 - 477796 - - - -0.5589 - 2.628 0.498 - 736.6 1 2 0 -0.0008 11 0 0 0 2.73E+06 3.19E+06 - - - 5.3328 0.9999 221125_WJC_METTL3_EV_vs_WT_F01.20252.20252.2 8.06E-05 14/24 K.LILLITQVTASEK[136.11].T sp|Q15061|WDR43_HUMAN 1 1435.8741 1.17 7723 20252 2 1435.874567 718.9443 WD repeat-containing protein 43 OS=Homo sapiens OX=9606 GN=WDR43 PE=1 SV=3 6 3752.7 - 398932 - - - 0.303 - 3.009 0.478 - 620 1 2 0 0.0004 13 0 0 0 4.86E+06 4.15E+06 - - - 5.3987 0.9998 221125_WJC_METTL3_EV_vs_WT_F01.20253.20253.2 1.03E-07 20-Oct R.LEYC[160.03]EALAMLR.E "sp|P14868|SYDC_HUMAN,tr|H7BZ35|H7BZ35_HUMAN" 2 1367.6577 0.86 7724 20253 2 1367.659793 684.8361 "Aspartate--tRNA ligase, cytoplasmic OS=Homo sapiens OX=9606 GN=DARS1 PE=1 SV=2" 4.53 3752.9 - 367248 - - - 1.4989 - 2.316 0.516 - 515.2 1 2 0 0.0021 11 0 0 0 2.73E+06 3.19E+06 - - - 5.1235 0.9993 221125_WJC_METTL3_EV_vs_WT_F01.20261.20261.2 2.67E-06 18-Sep K.GPDWILGEIK[136.11].T "sp|P49821|NDUV1_HUMAN,tr|G3V0I5|G3V0I5_HUMAN,tr|E9PPR0|E9PPR0_HUMAN,tr|E9PMX3|E9PMX3_HUMAN,tr|E9PQP1|E9PQP1_HUMAN,tr|E9PPS5|E9PPS5_HUMAN" 6 1134.6165 -1 7731 20261 2 1134.620226 568.3155 "NADH dehydrogenase [ubiquinone] flavoprotein 1, mitochondrial OS=Homo sapiens OX=9606 GN=NDUFV1 PE=1 SV=4" 4.37 3753.6 - 1.47E+06 - - - 3.3192 - 2.002 0.535 - 296.8 1 2 0 0.0038 10 0 0 0 0.00E+00 0.00E+00 - - - 4.9289 0.9274 221125_WJC_METTL3_EV_vs_WT_F01.20262.20262.2 0.0866 20-Aug L.SEGQVQLLLLR.L sp|Q5TH69|BIG3_HUMAN 1 1254.7296 9.6 7732 20262 2 1254.731361 628.3721 Brefeldin A-inhibited guanine nucleotide-exchange protein 3 OS=Homo sapiens OX=9606 GN=ARFGEF3 PE=1 SV=3 5.72 3753.6 - 1.47E+06 - - - 1.4146 - 1.624 0.301 - 185.7 1 1 0 0.0018 11 0 0 0 6.56E+06 6.83E+05 - - - 2.5754 0.9998 221125_WJC_METTL3_EV_vs_WT_F01.20263.20263.2 2.41E-05 20-Oct K.SIDPALSMLIK.S sp|Q9H501|ESF1_HUMAN 1 1186.6631 1.23 7733 20263 2 1186.664307 594.3388 ESF1 homolog OS=Homo sapiens OX=9606 GN=ESF1 PE=1 SV=1 5.55 3753.7 - 1.45E+06 - - - 0.9784 - 2.186 0.475 - 213.4 1 2 0 0.0012 11 0 0 0 7.95E+06 6.44E+06 - - - 4.6647 0.9999 221125_WJC_METTL3_EV_vs_WT_F01.20267.20267.2 0.00107 15/24 R.LAAVALINAAIQK.G "sp|P46940|IQGA1_HUMAN,tr|A0A0J9YXZ5|A0A0J9YXZ5_HUMAN" 2 1294.7973 0.76 7737 20267 2 1294.798406 648.4059 Ras GTPase-activating-like protein IQGAP1 OS=Homo sapiens OX=9606 GN=IQGAP1 PE=1 SV=1 8.75 3754.1 - 979615 - - - 0.8758 - 3.34 0.424 - 882.5 1 2 0 0.0011 13 0 0 0 4.47E+06 5.84E+06 - - - 5.2675 0.9998 221125_WJC_METTL3_EV_vs_WT_F01.20268.20268.2 0.00323 13/24 K.LILLITQVTASEK.T sp|Q15061|WDR43_HUMAN 1 1427.8599 1.17 7738 20268 2 1427.862319 714.9372 WD repeat-containing protein 43 OS=Homo sapiens OX=9606 GN=WDR43 PE=1 SV=3 6 3754.2 - 952553 - - - 1.6717 - 2.672 0.45 - 531.8 1 2 0 0.0024 13 0 0 0 4.86E+06 4.15E+06 - - - 4.8864 0.9989 221125_WJC_METTL3_EV_vs_WT_F01.20269.20269.2 0.00104 22-Nov R.LLTFMGMAVENK.E "sp|Q7L2H7|EIF3M_HUMAN,tr|H0YCQ8|H0YCQ8_HUMAN" 2 1352.6832 0.95 7739 20269 2 1352.685815 677.3489 Eukaryotic translation initiation factor 3 subunit M OS=Homo sapiens OX=9606 GN=EIF3M PE=1 SV=1 6 3754.3 - 909036 - - - 1.911 - 1.687 0.355 - 240.3 1 2 0 0.0026 12 0 0 0 8.28E+06 8.72E+06 - - - 3.0382 0.9998 221125_WJC_METTL3_EV_vs_WT_F01.20272.20272.2 0.00555 18-Oct K.ITIAAYLPLK.A sp|Q8TEM1|PO210_HUMAN 1 1101.6798 2.44 7742 20272 2 1101.681175 551.8472 Nuclear pore membrane glycoprotein 210 OS=Homo sapiens OX=9606 GN=NUP210 PE=1 SV=3 8.59 3754.7 - 672951 - - - 1.2644 - 2.205 0.487 - 247.3 1 2 0 0.0014 10 0 0 0 6.39E+06 2.62E+06 - - - 4.8447 0.9913 221125_WJC_METTL3_EV_vs_WT_F01.20273.20273.2 7.24E-06 22-Dec W.INTSDIILVGLR[166.11].D "sp|O14602|IF1AY_HUMAN,sp|P47813|IF1AX_HUMAN,tr|X6RAC9|X6RAC9_HUMAN" 3 1322.7797 0.76 7743 20273 2 1322.781399 662.3971 "Eukaryotic translation initiation factor 1A, Y-chromosomal OS=Homo sapiens OX=9606 GN=EIF1AY PE=1 SV=4" 5.84 3754.8 - 540224 - - - 1.2685 - 2.837 0.476 - 771 1 1 0 0.0017 12 0 0 0 1.38E+06 1.81E+06 - - - 5.2999 0.9735 221125_WJC_METTL3_EV_vs_WT_F01.20279.20279.2 0.0338 16-Jun K.C[160.03]EFQDAYVL.L "sp|P10809|CH60_HUMAN,tr|A0A7I2V2X6|A0A7I2V2X6_HUMAN,tr|A0A7I2YQK6|A0A7I2YQK6_HUMAN,tr|A0A7I2V599|A0A7I2V599_HUMAN,tr|A0A7I2YQ71|A0A7I2YQ71_HUMAN,tr|A0A7I2V5M1|A0A7I2V5M1_HUMAN,tr|A0A7I2V5K3|A0A7I2V5K3_HUMAN,tr|A0A7I2V369|A0A7I2V369_HUMAN" 8 1143.4907 - 7748 20279 2 1143.491393 572.7526 "60 kDa heat shock protein, mitochondrial OS=Homo sapiens OX=9606 GN=HSPD1 PE=1 SV=2" 3.67 3755.4 - 1.72E+06 - - - 0.6401 - 1.276 0.476 - 94.6 1 1 0 0.0007 9 0 0 0 - - - - - 3.2616 0.9998 221125_WJC_METTL3_EV_vs_WT_F01.20281.20281.2 0.000798 20-Dec R.IISLETYNLLR[166.11].E "sp|Q15149|PLEC_HUMAN,tr|H0YDN1|H0YDN1_HUMAN" 2 1343.7688 1.78 7750 20281 2 1343.769267 672.8917 Plectin OS=Homo sapiens OX=9606 GN=PLEC PE=1 SV=3 6 3755.5 - 1.35E+06 - - - 0.3312 - 2.167 0.398 - 465.9 1 2 0 0.0004 11 0 0 0 1.59E+07 8.93E+06 - - - 4.0726 0.9995 221125_WJC_METTL3_EV_vs_WT_F01.20285.20285.2 8.85E-05 18-Aug K.LLPFLSNPYR.N sp|Q13625|ASPP2_HUMAN 1 1218.6761 1.16 7754 20285 2 1218.675028 610.3453 Apoptosis-stimulating of p53 protein 2 OS=Homo sapiens OX=9606 GN=TP53BP2 PE=1 SV=2 8.75 3756 - 794736 - - - -0.8747 - 1.736 0.36 - 290.4 1 2 0 -0.0011 10 0 0 0 3.83E+06 3.30E+06 - - - 3.2393 0.9999 221125_WJC_METTL3_EV_vs_WT_F01.20287.20287.2 5.90E-05 22-Oct R.LFPPQWIC[160.03]C[160.03]DIR.Y sp|Q86U44|MTA70_HUMAN 1 1603.7639 0.02 7756 20287 2 1603.763686 802.8892 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 5.82 3756.3 - 613289 - - - -0.1584 - 2.036 0.529 - 283.2 1 2 0 -0.0003 12 0 0 0 2.07E+08 1.01E+10 - - - 4.8188 0.999 221125_WJC_METTL3_EV_vs_WT_F01.20290.20290.2 0.00586 20-Sep K.IGPITPLEFYR[166.11].E "sp|Q13867|BLMH_HUMAN,tr|K7ESE8|K7ESE8_HUMAN,tr|J3KSD8|J3KSD8_HUMAN,tr|K7ES02|K7ES02_HUMAN" 4 1314.7211 18.97 7759 20290 2 1314.721069 658.3678 Bleomycin hydrolase OS=Homo sapiens OX=9606 GN=BLMH PE=1 SV=1 6 3756.6 - 465165 - - - -0.0563 - 1.75 0.248 - 267.7 1 2 0 -0.0001 11 0 0 0 4.58E+07 2.41E+06 - - - 2.3866 0.9994 221125_WJC_METTL3_EV_vs_WT_F01.20293.20293.2 0.0186 12-Jun R.LASYLDK.V "sp|Q04695|K1C17_HUMAN,sp|Q99456|K1C12_HUMAN,sp|P13645|K1C10_HUMAN,sp|P02533|K1C14_HUMAN,sp|P08727|K1C19_HUMAN,sp|P35527|K1C9_HUMAN,sp|P08779|K1C16_HUMAN,sp|P19012|K1C15_HUMAN,tr|K7EPJ9|K7EPJ9_HUMAN,tr|C9JM50|C9JM50_HUMAN,tr|A0A1B0GVI3|A0A1B0GVI3_HUMAN,tr|A0A3B3ITG2|A0A3B3ITG2_HUMAN" 12 808.4331 132.01 7762 20293 2 808.43263 405.2238 "Keratin, type I cytoskeletal 17 OS=Homo sapiens OX=9606 GN=KRT17 PE=1 SV=2" 5.83 3757 - 252076 - - - -0.5443 - 1.422 0.369 - 114 1 2 0 -0.0004 7 0 0 0 9.33E+06 7.06E+04 - - - 2.8818 0.9951 221125_WJC_METTL3_EV_vs_WT_F01.20294.20294.2 0.223 Jul-34 K.IAIIGAGIGGTSAAYYLR.Q "sp|Q9UHG3|PCYOX_HUMAN,tr|F8W8W4|F8W8W4_HUMAN" 2 1765.9727 4.27 7763 20294 2 1765.972041 883.9936 Prenylcysteine oxidase 1 OS=Homo sapiens OX=9606 GN=PCYOX1 PE=1 SV=3 8.59 3757.2 - 232567 - - - -0.3562 - 1.47 0.189 - 60.8 4 2 0 -0.0006 18 0 0 0 1.39E+06 3.27E+05 - - - 1.115 0.9998 221125_WJC_METTL3_EV_vs_WT_F01.20296.20296.2 0.000134 20-Oct K.SIDPALSMLIK[136.11].S sp|Q9H501|ESF1_HUMAN 1 1194.6773 1.23 7764 20296 2 1194.676656 598.3459 ESF1 homolog OS=Homo sapiens OX=9606 GN=ESF1 PE=1 SV=1 5.55 3757.5 - 851575 - - - -0.5776 - 2.07 0.406 - 194.4 1 2 0 -0.0007 11 0 0 0 7.95E+06 6.44E+06 - - - 4.0077 1 221125_WJC_METTL3_EV_vs_WT_F01.20298.20298.3 3.41E-08 15/44 R.LFPPQWIC[160.03]C[160.03]DIR[166.11].Y sp|Q86U44|MTA70_HUMAN 1 1613.7722 0.02 7766 20298 3 1613.771883 538.9313 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 5.82 3757.6 - 3.43E+07 - - - -0.2026 - 2.589 0.633 - 340.2 1 2 0 -0.0003 12 0 0 0 4.73E+07 2.41E+09 - - - 8.234 0.9834 221125_WJC_METTL3_EV_vs_WT_F01.20299.20299.2 0.00319 14-Sep K.DIGFIK[136.11]LD.- "sp|P62273|RS29_HUMAN,tr|A0A087WTT6|A0A087WTT6_HUMAN" 2 927.5157 -1 7767 20299 2 927.514942 464.7651 40S ribosomal protein S29 OS=Homo sapiens OX=9606 GN=RPS29 PE=1 SV=2 4.54 3757.7 - 4.11E+06 - - - -0.8 - 1.474 0.257 - 145.1 1 2 1 -0.0007 8 0 0 0 0.00E+00 0.00E+00 - - - 2.1091 0.9888 221125_WJC_METTL3_EV_vs_WT_F01.20300.20300.2 0.00503 14-Oct K.DIGFIKLD.- "sp|P62273|RS29_HUMAN,tr|A0A087WTT6|A0A087WTT6_HUMAN" 2 919.5015 1.01 7768 20300 2 919.500872 460.758 40S ribosomal protein S29 OS=Homo sapiens OX=9606 GN=RPS29 PE=1 SV=2 4.54 3757.7 - 3.65E+06 - - - -0.6656 - 1.56 0.276 - 168 1 2 1 -0.0006 8 0 0 0 6.98E+06 6.90E+06 - - - 2.4205 0.9999 221125_WJC_METTL3_EV_vs_WT_F01.20302.20302.2 0.00959 15/24 R.GAVGALLVYDIAK[136.11].H "sp|Q15907|RB11B_HUMAN,sp|P62491|RB11A_HUMAN,tr|H3BMH2|H3BMH2_HUMAN,tr|H3BSC1|H3BSC1_HUMAN" 4 1296.7533 1.03 7770 20302 2 1296.751424 649.3839 Ras-related protein Rab-11B OS=Homo sapiens OX=9606 GN=RAB11B PE=1 SV=4 5.83 3757.8 - 2.35E+06 - - - -1.4374 - 3.088 0.467 - 1262 1 2 0 -0.0019 13 0 0 0 1.35E+08 1.31E+08 - - - 5.3835 1 221125_WJC_METTL3_EV_vs_WT_F01.20303.20303.2 4.81E-09 16/24 R.GAVGALLVYDIAK.H "sp|Q15907|RB11B_HUMAN,sp|P62491|RB11A_HUMAN,tr|H3BMH2|H3BMH2_HUMAN,tr|H3BSC1|H3BSC1_HUMAN" 4 1288.7391 1.03 7771 20303 2 1288.739752 645.3768 Ras-related protein Rab-11B OS=Homo sapiens OX=9606 GN=RAB11B PE=1 SV=4 5.83 3757.9 - 2.27E+06 - - - 0.5152 - 3.262 0.574 - 1538.1 1 2 0 0.0007 13 0 0 0 1.36E+08 1.32E+08 - - - 6.3149 0.9998 221125_WJC_METTL3_EV_vs_WT_F01.20304.20304.2 1.45E-06 22-Oct K.LNGFQLENFTLK.V sp|O00425|IF2B3_HUMAN 1 1422.7507 2.36 7772 20304 2 1422.749929 712.3826 Insulin-like growth factor 2 mRNA-binding protein 3 OS=Homo sapiens OX=9606 GN=IGF2BP3 PE=1 SV=2 6 3758 - 1.33E+06 - - - -0.5532 - 2.248 0.446 - 370 1 2 0 -0.0008 12 0 0 0 1.19E+07 5.01E+06 - - - 4.4663 1 221125_WJC_METTL3_EV_vs_WT_F01.20305.20305.2 3.06E-07 16/18 F.PPQWIC[160.03]C[160.03]DIR[166.11].Y sp|Q86U44|MTA70_HUMAN 1 1353.6197 0 7773 20305 2 1353.618765 677.8171 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 6.18 3758.1 - 1.23E+06 - - - -0.7144 - 2.936 0.53 - 1022.4 1 1 0 -0.001 10 0 0 0 2.26E+05 1.04E+08 - - - 5.9616 0.9994 221125_WJC_METTL3_EV_vs_WT_F01.20306.20306.2 0.00378 18-Oct K.INEWLTLVEK[136.11].E "sp|Q14204|DYHC1_HUMAN,tr|A0A7P0T8N2|A0A7P0T8N2_HUMAN,tr|A0A7P0T9C4|A0A7P0T9C4_HUMAN,tr|A0A7P0TBJ7|A0A7P0TBJ7_HUMAN,tr|A0A804HHY6|A0A804HHY6_HUMAN,tr|A0A7P0T9K2|A0A7P0T9K2_HUMAN,tr|A0A7P0TB64|A0A7P0TB64_HUMAN,tr|A0A2R8Y706|A0A2R8Y706_HUMAN,tr|A0A7P0T916|A0A7P0T916_HUMAN,tr|A0A7P0TB75|A0A7P0TB75_HUMAN,tr|A0A7P0T8W5|A0A7P0T8W5_HUMAN,tr|A0A7P0T9S3|A0A7P0T9S3_HUMAN,tr|A0A7P0TAF3|A0A7P0TAF3_HUMAN,tr|A0A7P0T9F1|A0A7P0T9F1_HUMAN,tr|A0A7P0TAW9|A0A7P0TAW9_HUMAN,tr|A0A2R8YGC7|A0A2R8YGC7_HUMAN,tr|A0A7P0TA13|A0A7P0TA13_HUMAN,tr|A0A7P0T934|A0A7P0T934_HUMAN,tr|A0A7P0TAV5|A0A7P0TAV5_HUMAN,tr|A0A7P0T7V5|A0A7P0T7V5_HUMAN,tr|A0A7P0T9R4|A0A7P0T9R4_HUMAN,tr|A0A2R8Y5T0|A0A2R8Y5T0_HUMAN,tr|A0A7P0T990|A0A7P0T990_HUMAN,tr|A0A7P0T942|A0A7P0T942_HUMAN,tr|A0A2R8YFZ7|A0A2R8YFZ7_HUMAN,tr|A0A7P0T825|A0A7P0T825_HUMAN,tr|A0A2R8Y6H2|A0A2R8Y6H2_HUMAN,tr|A0A7P0TAM4|A0A7P0TAM4_HUMAN" 28 1251.6954 1.09 7774 20306 2 1251.697215 626.855 Cytoplasmic dynein 1 heavy chain 1 OS=Homo sapiens OX=9606 GN=DYNC1H1 PE=1 SV=5 4.53 3758.1 - 1.17E+06 - - - 1.4189 - 1.743 0.384 - 324 1 2 0 0.0018 10 0 0 0 6.92E+06 6.35E+06 - - - 3.4275 0.9996 221125_WJC_METTL3_EV_vs_WT_F01.20307.20307.2 0.00122 16-Aug R.LVFGFLNGR.A "sp|P00491|PNPH_HUMAN,tr|G3V2H3|G3V2H3_HUMAN,tr|G3V5M2|G3V5M2_HUMAN" 3 1021.5709 4.56 7775 20307 2 1021.571509 511.7927 Purine nucleoside phosphorylase OS=Homo sapiens OX=9606 GN=PNP PE=1 SV=2 9.75 3758.2 - 1.13E+06 - - - 0.5952 - 1.661 0.408 - 220.5 1 2 0 0.0006 9 0 0 0 9.53E+06 2.09E+06 - - - 3.5223 0.9999 221125_WJC_METTL3_EV_vs_WT_F01.20310.20310.2 2.79E-05 22-Dec K.LNGFQLENFTLK[136.11].V sp|O00425|IF2B3_HUMAN 1 1430.7649 2.36 7778 20310 2 1430.764008 716.3897 Insulin-like growth factor 2 mRNA-binding protein 3 OS=Homo sapiens OX=9606 GN=IGF2BP3 PE=1 SV=2 6 3758.6 - 910214 - - - -0.6346 - 2.651 0.48 - 622.3 1 2 0 -0.0009 12 0 0 0 1.19E+07 5.01E+06 - - - 5.1512 0.9994 221125_WJC_METTL3_EV_vs_WT_F01.20311.20311.2 1.97E-05 22-Nov R.DLAQDEAVWLER.G "sp|P29372|3MG_HUMAN,tr|A2IDA3|A2IDA3_HUMAN" 2 1443.6994 -1 7779 20311 2 1443.69593 722.857 DNA-3-methyladenine glycosylase OS=Homo sapiens OX=9606 GN=MPG PE=1 SV=3 3.92 3758.7 - 666728 - - - -2.4091 - 2.466 0.367 - 463 1 2 0 -0.0035 12 0 0 0 0.00E+00 0.00E+00 - - - 4.1255 0.9946 221125_WJC_METTL3_EV_vs_WT_F01.20318.20318.2 3.66E-06 22-Oct R.IRDLLYEQYAIV.- sp|Q9P2I0|CPSF2_HUMAN 1 1494.8082 0.65 7785 20318 2 1494.804155 748.4114 Cleavage and polyadenylation specificity factor subunit 2 OS=Homo sapiens OX=9606 GN=CPSF2 PE=1 SV=2 4.37 3759.5 - 675649 - - - -2.7261 - 1.933 0.533 - 246 1 2 1 -0.0041 12 0 0 0 3.34E+06 5.12E+06 - - - 4.7106 0.9997 221125_WJC_METTL3_EV_vs_WT_F01.20321.20321.2 0.000249 20-Oct R.IISLETYNLLR.E "sp|Q15149|PLEC_HUMAN,tr|H0YDN1|H0YDN1_HUMAN" 2 1333.7606 1.78 7788 20321 2 1333.758256 667.8876 Plectin OS=Homo sapiens OX=9606 GN=PLEC PE=1 SV=3 6 3759.7 - 3.34E+06 - - - -1.7214 - 2.08 0.484 - 346.5 1 2 0 -0.0023 11 0 0 0 1.59E+07 8.93E+06 - - - 4.5963 0.9997 221125_WJC_METTL3_EV_vs_WT_F01.20322.20322.2 8.39E-05 22-Sep R.IMVANIEEVLQR.G "sp|O75396|SC22B_HUMAN,tr|A0A087X1A9|A0A087X1A9_HUMAN" 2 1413.765 40.93 7789 20322 2 1413.761766 707.8898 Vesicle-trafficking protein SEC22b OS=Homo sapiens OX=9606 GN=SEC22B PE=1 SV=5 4.53 3759.7 - 2.07E+06 - - - -2.2769 - 2.405 0.459 - 303 1 2 0 -0.0032 12 0 0 0 8.53E+07 2.08E+06 - - - 4.7391 1 221125_WJC_METTL3_EV_vs_WT_F01.20323.20323.2 5.02E-07 13/18 K.VLEAELLVLR.Q sp|P07196|NFL_HUMAN 1 1153.7071 1.97 7790 20323 2 1153.705503 577.8608 Neurofilament light polypeptide OS=Homo sapiens OX=9606 GN=NEFL PE=1 SV=3 4.53 3759.9 - 1.49E+06 - - - -1.3496 - 2.658 0.594 - 662.8 1 2 0 -0.0016 10 0 0 0 8.21E+07 4.17E+07 - - - 6.1565 0.9999 221125_WJC_METTL3_EV_vs_WT_F01.20324.20324.3 0.00408 15/48 R.GAVGALLVYDIAK.H "sp|Q15907|RB11B_HUMAN,sp|P62491|RB11A_HUMAN,tr|H3BMH2|H3BMH2_HUMAN,tr|H3BSC1|H3BSC1_HUMAN" 4 1288.7391 0.96 7791 20324 3 1288.736997 430.587 Ras-related protein Rab-11B OS=Homo sapiens OX=9606 GN=RAB11B PE=1 SV=4 5.83 3760 - 1.09E+06 - - - -1.6225 - 2.709 0.427 - 417.1 1 2 0 -0.0021 13 0 0 0 7.85E+06 8.20E+06 - - - 6.0021 0.9996 221125_WJC_METTL3_EV_vs_WT_F01.20326.20326.2 5.18E-05 18-Dec K.VLEAELLVLR[166.11].Q sp|P07196|NFL_HUMAN 1 1163.7153 1.97 7793 20326 2 1163.713806 582.8649 Neurofilament light polypeptide OS=Homo sapiens OX=9606 GN=NEFL PE=1 SV=3 4.53 3760.2 - 830425 - - - -1.3096 - 2.222 0.338 - 557.6 1 2 0 -0.0015 10 0 0 0 8.21E+07 4.17E+07 - - - 3.7656 0.9946 221125_WJC_METTL3_EV_vs_WT_F01.20330.20330.2 0.000165 22-Aug R.IR[166.11]DLLYEQYAIV.- sp|Q9P2I0|CPSF2_HUMAN 1 1504.8165 0.65 7797 20330 2 1504.813421 753.4155 Cleavage and polyadenylation specificity factor subunit 2 OS=Homo sapiens OX=9606 GN=CPSF2 PE=1 SV=2 4.37 3760.7 - 598799 - - - -2.0461 - 1.823 0.453 - 125.8 1 2 1 -0.0031 12 0 0 0 3.34E+06 5.12E+06 - - - 3.9659 0.9995 221125_WJC_METTL3_EV_vs_WT_F01.20331.20331.2 0.00563 24-Oct K.LFDVPSLNGVYPR.M "sp|Q8NHQ1|CEP70_HUMAN,tr|B7Z2D2|B7Z2D2_HUMAN" 2 1475.7773 999 7798 20331 2 1475.779547 738.8959 Centrosomal protein of 70 kDa OS=Homo sapiens OX=9606 GN=CEP70 PE=1 SV=2 5.84 3760.8 - 288909 - - - 1.5463 - 1.807 0.422 - 255.1 1 2 0 0.0023 13 0 0 0 2.15E+06 0.00E+00 - - - 3.6757 0.9921 221125_WJC_METTL3_EV_vs_WT_F01.20333.20333.2 0.133 18-Jul R.EYLLDMIPPR.S "sp|Q86YP4|P66A_HUMAN,sp|Q8WXI9|P66B_HUMAN,tr|A0A0U1RRM1|A0A0U1RRM1_HUMAN" 3 1245.6427 1.33 7799 20333 2 1245.641641 623.8286 Transcriptional repressor p66-alpha OS=Homo sapiens OX=9606 GN=GATAD2A PE=1 SV=1 4.37 3761.1 - 933581 - - - -0.8863 - 1.419 0.116 - 164.2 1 2 0 -0.0011 10 0 0 0 2.66E+07 2.01E+07 - - - 0.8743 0.998 221125_WJC_METTL3_EV_vs_WT_F01.20335.20335.2 0.0282 16-Sep K.EIIDLVLDR.L "sp|Q71U36|TBA1A_HUMAN,sp|P68363|TBA1B_HUMAN,sp|Q9BQE3|TBA1C_HUMAN,tr|F8VS66|F8VS66_HUMAN,tr|F8VRZ4|F8VRZ4_HUMAN,tr|F8VVB9|F8VVB9_HUMAN,tr|A0A1W2PQM2|A0A1W2PQM2_HUMAN,tr|F5H5D3|F5H5D3_HUMAN,tr|F8VQQ4|F8VQQ4_HUMAN" 9 1084.6128 0.64 7800 20335 2 1084.610183 543.3137 Tubulin alpha-1A chain OS=Homo sapiens OX=9606 GN=TUBA1A PE=1 SV=1 4.03 3761.3 - 1.22E+07 - - - -2.4359 - 1.835 0.264 - 360 1 2 0 -0.0026 9 0 0 0 3.54E+08 5.55E+08 - - - 2.7463 0.9998 221125_WJC_METTL3_EV_vs_WT_F01.20336.20336.2 0.00436 13/22 K.VESLQEEIAFLK.K "sp|P08670|VIME_HUMAN,tr|B0YJC5|B0YJC5_HUMAN,tr|B0YJC4|B0YJC4_HUMAN" 3 1404.75 1.84 7801 20336 2 1404.748205 703.3823 Vimentin OS=Homo sapiens OX=9606 GN=VIM PE=1 SV=4 4.25 3761.4 - 2.48E+06 - - - -1.3113 - 2.375 0.464 - 433.1 1 2 0 -0.0018 12 0 0 0 1.85E+08 1.01E+08 - - - 4.7435 0.9989 221125_WJC_METTL3_EV_vs_WT_F01.20341.20341.2 0.0532 22-Aug K.VILLDPSIIEAK[136.11].M sp|Q07617|SPAG1_HUMAN 1 1317.7999 0.88 7806 20341 2 1317.798987 659.9072 Sperm-associated antigen 1 OS=Homo sapiens OX=9606 GN=SPAG1 PE=1 SV=3 4.37 3762 - 636514 - - - -0.6959 - 1.376 0.334 - 105.3 1 2 0 -0.0009 12 0 0 0 3.23E+06 3.67E+06 - - - 2.3475 0.9994 221125_WJC_METTL3_EV_vs_WT_F01.20345.20345.2 0.0881 16-Sep K.EIIDLVLDR[166.11].L "sp|Q71U36|TBA1A_HUMAN,sp|P68363|TBA1B_HUMAN,sp|Q9BQE3|TBA1C_HUMAN,tr|F8VS66|F8VS66_HUMAN,tr|F8VRZ4|F8VRZ4_HUMAN,tr|F8VVB9|F8VVB9_HUMAN,tr|A0A1W2PQM2|A0A1W2PQM2_HUMAN,tr|F5H5D3|F5H5D3_HUMAN,tr|F8VQQ4|F8VQQ4_HUMAN" 9 1094.6211 0.64 7809 20345 2 1094.619759 548.3178 Tubulin alpha-1A chain OS=Homo sapiens OX=9606 GN=TUBA1A PE=1 SV=1 4.03 3762.5 - 4.09E+07 - - - -1.2205 - 1.836 0.324 - 371.6 1 2 0 -0.0013 9 0 0 0 3.54E+08 5.55E+08 - - - 3.1914 0.9966 221125_WJC_METTL3_EV_vs_WT_F01.20346.20346.2 9.14E-05 18-Oct K.TLQIFNIEMK.S "sp|Q00610|CLH1_HUMAN,sp|P53675|CLH2_HUMAN,tr|J3KSQ2|J3KSQ2_HUMAN,tr|J3KS13|J3KS13_HUMAN,tr|A0A087WVQ6|A0A087WVQ6_HUMAN,tr|F5H5N6|F5H5N6_HUMAN,tr|A0A087WX41|A0A087WX41_HUMAN" 7 1235.6584 0.84 7810 20346 2 1235.653391 618.8365 Clathrin heavy chain 1 OS=Homo sapiens OX=9606 GN=CLTC PE=1 SV=5 5.66 3762.6 - 1.10E+06 - - - -4.0497 - 1.913 0.343 - 280.3 1 2 0 -0.005 10 0 0 0 6.08E+06 7.28E+06 - - - 3.3835 0.9994 221125_WJC_METTL3_EV_vs_WT_F01.20350.20350.2 0.00129 20-Oct K.GIFNGFSVTLK[136.11].E "sp|Q00325|MPCP_HUMAN,tr|F8VWR4|F8VWR4_HUMAN,tr|F8VVM2|F8VVM2_HUMAN,tr|F8VWQ0|F8VWQ0_HUMAN" 4 1189.6587 0.8 7814 20350 2 1189.66027 595.8366 "Phosphate carrier protein, mitochondrial OS=Homo sapiens OX=9606 GN=SLC25A3 PE=1 SV=2" 8.75 3763 - 1.78E+06 - - - 1.3542 - 1.864 0.341 - 230.5 1 2 0 0.0016 11 0 0 0 1.08E+07 1.35E+07 - - - 3.2437 0.9987 221125_WJC_METTL3_EV_vs_WT_F01.20351.20351.2 0.00806 13/22 K.TVTAMDVVYALK[136.11].R sp|P62805|H4_HUMAN 1 1317.7094 1 7815 20351 2 1317.703615 659.862 Histone H4 OS=Homo sapiens OX=9606 GN=H4C1 PE=1 SV=2 5.5 3763.1 - 1.76E+06 - - - -4.3712 - 2.549 0.484 - 344.5 1 2 0 -0.0058 12 0 0 0 1.18E+09 1.19E+09 - - - 5.076 0.9996 221125_WJC_METTL3_EV_vs_WT_F01.20353.20353.2 0.00205 16-Oct R.LVSYYYFLR.F sp|Q7LGA3|HS2ST_HUMAN 1 1222.6386 1.05 7817 20353 2 1222.640784 612.3266 Heparan sulfate 2-O-sulfotransferase 1 OS=Homo sapiens OX=9606 GN=HS2ST1 PE=1 SV=1 8.5 3763.3 - 1.52E+06 - - - 1.7487 - 1.715 0.451 - 349.7 1 2 0 0.0021 9 0 0 0 7.16E+07 6.83E+07 - - - 3.932 0.9979 221125_WJC_METTL3_EV_vs_WT_F01.20354.20354.2 2.07E-06 16-Oct K.C[160.03]MPTFQFFK[136.11].K sp|P10599|THIO_HUMAN 1 1212.5551 0.68 7818 20354 2 1212.549749 607.2848 Thioredoxin OS=Homo sapiens OX=9606 GN=TXN PE=1 SV=3 8.22 3763.4 - 1.40E+06 - - - -4.432 - 1.714 0.51 - 233.4 1 2 0 -0.0054 9 0 0 0 1.96E+08 2.90E+08 - - - 4.365 0.9995 221125_WJC_METTL3_EV_vs_WT_F01.20358.20358.2 2.32E-05 22-Jul R.LFPPQWIC[160.03]C[160.03]DIR[166.11].Y sp|Q86U44|MTA70_HUMAN 1 1613.7722 0.02 7821 20358 2 1613.767939 807.8934 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 5.82 3763.9 - 3.36E+08 - - - -2.6466 - 1.87 0.518 - 116.8 1 2 0 -0.0043 12 0 0 0 2.07E+08 1.01E+10 - - - 4.5126 0.9996 221125_WJC_METTL3_EV_vs_WT_F01.20360.20360.2 6.82E-06 22-Dec K.TVTAMDVVYALK.R sp|P62805|H4_HUMAN 1 1309.6952 1 7822 20360 2 1309.690987 655.8549 Histone H4 OS=Homo sapiens OX=9606 GN=H4C1 PE=1 SV=2 5.5 3764.1 - 7.83E+06 - - - -3.1977 - 2.461 0.569 - 301 1 2 0 -0.0042 12 0 0 0 1.19E+09 1.19E+09 - - - 5.6119 0.9991 221125_WJC_METTL3_EV_vs_WT_F01.20362.20362.2 2.48E-07 16-Sep K.C[160.03]MPTFQFFK.K sp|P10599|THIO_HUMAN 1 1204.5409 0.68 7824 20362 2 1204.536277 603.2777 Thioredoxin OS=Homo sapiens OX=9606 GN=TXN PE=1 SV=3 8.22 3764.2 - 4.77E+06 - - - -3.8571 - 1.831 0.592 - 194.3 1 2 0 -0.0046 9 0 0 0 1.96E+08 2.90E+08 - - - 5.162 1 221125_WJC_METTL3_EV_vs_WT_F01.20363.20363.2 5.32E-05 18/26 R.YSALFLGVAYGATR.Y sp|P56385|ATP5I_HUMAN 1 1487.7773 1.62 7825 20363 2 1487.770321 744.8959 "ATP synthase subunit e, mitochondrial OS=Homo sapiens OX=9606 GN=ATP5ME PE=1 SV=2" 8.59 3764.4 - 2.74E+06 - - - -4.6674 - 2.956 0.557 - 1087.5 1 2 0 -0.0069 14 0 0 0 6.57E+07 4.04E+07 - - - 5.8727 0.9995 221125_WJC_METTL3_EV_vs_WT_F01.20364.20364.2 5.67E-05 13/20 K.FMELLEPLNER.K "sp|Q01082|SPTB2_HUMAN,tr|A0A087WUZ3|A0A087WUZ3_HUMAN" 2 1389.6962 1.76 7826 20364 2 1389.691984 695.8554 "Spectrin beta chain, non-erythrocytic 1 OS=Homo sapiens OX=9606 GN=SPTBN1 PE=1 SV=2" 4.25 3764.5 - 2.65E+06 - - - -3.0604 - 2.346 0.509 - 723 1 2 0 -0.0043 11 0 0 0 2.90E+07 1.65E+07 - - - 5.1059 0.988 221125_WJC_METTL3_EV_vs_WT_F01.20365.20365.2 0.00327 18-Dec K.MAEMLVELVR.R sp|Q9Y605|MOFA1_HUMAN 1 1189.6199 3.63 7827 20365 2 1189.610354 595.8172 MORF4 family-associated protein 1 OS=Homo sapiens OX=9606 GN=MRFAP1 PE=1 SV=1 4.53 3764.6 - 2.42E+06 - - - -8.0253 - 2.442 0.523 - 658.3 1 2 0 -0.0095 10 0 0 0 9.26E+07 2.55E+07 - - - 5.393 1 221125_WJC_METTL3_EV_vs_WT_F01.20369.20369.2 5.90E-10 15/26 R.YSALFLGVAYGATR[166.11].Y sp|P56385|ATP5I_HUMAN 1 1497.7855 1.62 7831 20369 2 1497.782064 749.9 "ATP synthase subunit e, mitochondrial OS=Homo sapiens OX=9606 GN=ATP5ME PE=1 SV=2" 8.59 3765.1 - 1.48E+06 - - - -2.3174 - 2.804 0.627 - 706.6 1 2 0 -0.0035 14 0 0 0 6.57E+07 4.04E+07 - - - 6.2583 0.9998 221125_WJC_METTL3_EV_vs_WT_F01.20376.20376.3 3.29E-06 17/44 K.TVTAMDVVYALK[136.11].R sp|P62805|H4_HUMAN 1 1317.7094 1.02 7836 20376 3 1317.702818 440.2437 Histone H4 OS=Homo sapiens OX=9606 GN=H4C1 PE=1 SV=2 5.5 3765.9 - 3.35E+06 - - - -4.9761 - 2.824 0.559 - 536.8 1 2 0 -0.0066 12 0 0 0 1.04E+08 1.03E+08 - - - 7.6481 1 221125_WJC_METTL3_EV_vs_WT_F01.20377.20377.3 3.80E-09 18/44 K.TVTAMDVVYALK.R sp|P62805|H4_HUMAN 1 1309.6952 1.02 7837 20377 3 1309.694633 437.5723 Histone H4 OS=Homo sapiens OX=9606 GN=H4C1 PE=1 SV=2 5.5 3766 - 2.63E+06 - - - -0.4138 - 2.926 0.574 - 601.5 1 2 0 -0.0005 12 0 0 0 1.04E+08 1.03E+08 - - - 7.9153 0.9994 221125_WJC_METTL3_EV_vs_WT_F01.20378.20378.2 0.0235 13/18 K.MAEMLVELVR[166.11].R sp|Q9Y605|MOFA1_HUMAN 1 1199.6282 3.63 7838 20378 2 1199.625269 600.8214 MORF4 family-associated protein 1 OS=Homo sapiens OX=9606 GN=MRFAP1 PE=1 SV=1 4.53 3766.2 - 1.51E+06 - - - -2.4191 - 2.506 0.345 - 1019.2 1 2 0 -0.0029 10 0 0 0 9.26E+07 2.55E+07 - - - 4.1526 0.9986 221125_WJC_METTL3_EV_vs_WT_F01.20379.20379.2 1.88E-05 20-Nov K.GIFNGFSVTLK.E "sp|Q00325|MPCP_HUMAN,tr|F8VWR4|F8VWR4_HUMAN,tr|F8VVM2|F8VVM2_HUMAN,tr|F8VWQ0|F8VWQ0_HUMAN" 4 1181.6445 0.8 7839 20379 2 1181.64 591.8295 "Phosphate carrier protein, mitochondrial OS=Homo sapiens OX=9606 GN=SLC25A3 PE=1 SV=2" 8.75 3766.3 - 1.48E+06 - - - -3.7736 - 2.083 0.437 - 315.9 1 2 0 -0.0045 11 0 0 0 1.08E+07 1.35E+07 - - - 4.2524 0.9974 221125_WJC_METTL3_EV_vs_WT_F01.20380.20380.2 0.108 16-Aug K.DVMDALILK[136.11].M sp|Q8N1G4|LRC47_HUMAN 1 1024.5718 0.55 7840 20380 2 1024.570693 513.2932 Leucine-rich repeat-containing protein 47 OS=Homo sapiens OX=9606 GN=LRRC47 PE=1 SV=1 4.21 3766.4 - 1.33E+06 - - - -1.098 - 1.367 0.245 - 154.4 1 2 0 -0.0011 9 0 0 0 2.60E+07 4.71E+07 - - - 1.7546 0.9916 221125_WJC_METTL3_EV_vs_WT_F01.20381.20381.2 0.0241 16-Aug K.DVMDALILK.M sp|Q8N1G4|LRC47_HUMAN 1 1016.5576 0.56 7841 20381 2 1016.554041 509.2861 Leucine-rich repeat-containing protein 47 OS=Homo sapiens OX=9606 GN=LRRC47 PE=1 SV=1 4.21 3766.5 - 1.17E+06 - - - -3.5187 - 1.368 0.299 - 146.1 1 2 0 -0.0036 9 0 0 0 2.63E+07 4.73E+07 - - - 2.1548 1 221125_WJC_METTL3_EV_vs_WT_F01.20386.20386.2 1.40E-11 15/28 K.GVYPDLLATSGDYLR[166.11].V sp|P61962|DCAF7_HUMAN 1 1648.8336 1.28 7844 20386 2 1648.82624 825.4241 DDB1- and CUL4-associated factor 7 OS=Homo sapiens OX=9606 GN=DCAF7 PE=1 SV=1 4.21 3767.2 - 2.79E+06 - - - -4.468 - 2.79 0.661 - 587.6 1 2 0 -0.0074 15 0 0 0 1.75E+08 1.36E+08 - - - 6.4434 1 221125_WJC_METTL3_EV_vs_WT_F01.20387.20387.2 1.68E-05 16/28 K.GVYPDLLATSGDYLR.V sp|P61962|DCAF7_HUMAN 1 1638.8253 1.29 7845 20387 2 1638.823754 820.4199 DDB1- and CUL4-associated factor 7 OS=Homo sapiens OX=9606 GN=DCAF7 PE=1 SV=1 4.21 3767.3 - 2.77E+06 - - - -0.9659 - 2.726 0.623 - 579.9 1 2 0 -0.0016 15 0 0 0 1.75E+08 1.36E+08 - - - 6.1075 1 221125_WJC_METTL3_EV_vs_WT_F01.20394.20394.2 7.09E-09 13/22 R.VALDMTTLTIMR[166.11].Y "sp|P62333|PRS10_HUMAN,tr|A0A087X2I1|A0A087X2I1_HUMAN,tr|H0YJC0|H0YJC0_HUMAN,tr|H0YJS8|H0YJS8_HUMAN" 4 1373.7286 0.55 7850 20394 2 1373.727375 687.8716 26S proteasome regulatory subunit 10B OS=Homo sapiens OX=9606 GN=PSMC6 PE=1 SV=1 5.81 3768.1 - 1.67E+06 - - - -0.9012 - 2.806 0.587 - 766 1 2 0 -0.0012 12 0 0 0 1.65E+07 2.98E+07 - - - 6.0909 0.9994 221125_WJC_METTL3_EV_vs_WT_F01.20397.20397.2 1.01E-05 20-Dec K.YFFFDDGNGLK[136.11].G sp|P61009|SPCS3_HUMAN 1 1329.6121 1.4 7851 20397 2 1329.607621 665.8133 Signal peptidase complex subunit 3 OS=Homo sapiens OX=9606 GN=SPCS3 PE=1 SV=1 4.21 3768.5 - 1.67E+06 - - - -3.3709 - 2.051 0.565 - 368.6 1 2 0 -0.0045 11 0 0 0 4.03E+07 2.89E+07 - - - 5.1559 0.8405 221125_WJC_METTL3_EV_vs_WT_F01.20400.20400.2 1.08 26-Jul K.TKPLAER[166.11]SIVPQTK[136.11].S sp|Q6P1M9|ARMX5_HUMAN 1 1584.9318 - 7854 20400 2 1584.931696 793.4732 Armadillo repeat-containing X-linked protein 5 OS=Homo sapiens OX=9606 GN=ARMCX5 PE=1 SV=1 9.99 3768.8 - 2.47E+06 - - - -0.0732 - 1.311 0.075 - 78.2 1 2 1 -0.0001 14 0 0 0 - - - - - 0.2744 1 221125_WJC_METTL3_EV_vs_WT_F01.20401.20401.2 4.70E-05 19/30 K.IITLEEGDIILTGTPK[136.11].G sp|Q6P587|FAHD1_HUMAN 1 1719.975 1.16 7855 20401 2 1719.970037 860.9948 "Acylpyruvase FAHD1, mitochondrial OS=Homo sapiens OX=9606 GN=FAHD1 PE=1 SV=2" 4.14 3768.9 - 1.41E+06 - - - -2.8669 - 3.386 0.58 - 1089.5 1 2 0 -0.0049 16 0 0 0 2.74E+07 2.38E+07 - - - 6.3219 1 221125_WJC_METTL3_EV_vs_WT_F01.20402.20402.3 1.78E-05 14/60 K.IITLEEGDIILTGTPK.G sp|Q6P587|FAHD1_HUMAN 1 1711.9608 0.87 7856 20402 3 1711.959816 571.6609 "Acylpyruvase FAHD1, mitochondrial OS=Homo sapiens OX=9606 GN=FAHD1 PE=1 SV=2" 4.14 3769.1 - 1.10E+06 - - - -0.5561 - 2.772 0.495 - 281.9 1 2 0 -0.001 16 0 0 0 1.66E+07 1.90E+07 - - - 6.6746 1 221125_WJC_METTL3_EV_vs_WT_F01.20403.20403.3 6.09E-09 17/56 K.GVYPDLLATSGDYLR[166.11].V sp|P61962|DCAF7_HUMAN 1 1648.8336 1.22 7857 20403 3 1648.829838 550.6185 DDB1- and CUL4-associated factor 7 OS=Homo sapiens OX=9606 GN=DCAF7 PE=1 SV=1 4.21 3769.2 - 1.09E+06 - - - -2.2859 - 2.745 0.597 - 264.6 1 2 0 -0.0038 15 0 0 0 2.59E+07 2.13E+07 - - - 7.8298 0.9848 221125_WJC_METTL3_EV_vs_WT_F01.20404.20404.2 0.00161 12-Aug Q.WIC[160.03]C[160.03]DIR[166.11].Y sp|Q86U44|MTA70_HUMAN 1 1031.4556 0.001 7858 20404 2 1031.455202 516.7351 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 5.82 3769.3 - 0 - - - -0.412 - 1.648 0.427 - 378.8 1 1 0 -0.0004 7 0 0 0 0.00E+00 1.70E+07 - - - 3.7776 1 221125_WJC_METTL3_EV_vs_WT_F01.20410.20410.2 6.35E-10 21/30 K.IITLEEGDIILTGTPK.G sp|Q6P587|FAHD1_HUMAN 1 1711.9608 1.16 7862 20410 2 1711.959381 856.9877 "Acylpyruvase FAHD1, mitochondrial OS=Homo sapiens OX=9606 GN=FAHD1 PE=1 SV=2" 4.14 3770 - 2.01E+06 - - - -0.8102 - 3.75 0.668 - 1384.7 1 2 0 -0.0014 16 0 0 0 2.74E+07 2.38E+07 - - - 7.224 0.9975 221125_WJC_METTL3_EV_vs_WT_F01.20411.20411.2 1.83E-05 14-Sep K.FGFYEVFK[136.11].V "sp|Q00325|MPCP_HUMAN,tr|F8VWR4|F8VWR4_HUMAN,tr|F8VVM2|F8VVM2_HUMAN,tr|F8VWQ0|F8VWQ0_HUMAN" 4 1043.5208 0.66 7863 20411 2 1043.51642 522.7677 "Phosphate carrier protein, mitochondrial OS=Homo sapiens OX=9606 GN=SLC25A3 PE=1 SV=2" 6 3770.1 - 1.90E+06 - - - -4.1676 - 1.763 0.424 - 175.1 1 2 0 -0.0043 8 0 0 0 1.50E+07 2.26E+07 - - - 3.8814 0.9993 221125_WJC_METTL3_EV_vs_WT_F01.20412.20412.2 0.0113 18-Nov R.LGGIAYFLSR[166.11].L "sp|Q9H2U1|DHX36_HUMAN,tr|E7EWK3|E7EWK3_HUMAN" 2 1105.616 1.49 7864 20412 2 1105.613732 553.8153 ATP-dependent DNA\RNA helicase DHX36 OS=Homo sapiens OX=9606 GN=DHX36 PE=1 SV=2 8.75 3770.2 - 1.84E+06 - - - -2.0061 - 2.031 0.332 - 326.4 1 2 0 -0.0022 10 0 0 0 2.20E+07 1.48E+07 - - - 3.4702 1 221125_WJC_METTL3_EV_vs_WT_F01.20413.20413.3 1.57E-06 16/60 K.IITLEEGDIILTGTPK[136.11].G sp|Q6P587|FAHD1_HUMAN 1 1719.975 0.87 7865 20413 3 1719.972606 574.3323 "Acylpyruvase FAHD1, mitochondrial OS=Homo sapiens OX=9606 GN=FAHD1 PE=1 SV=2" 4.14 3770.3 - 1.80E+06 - - - -1.3733 - 2.574 0.535 - 293 1 2 0 -0.0024 16 0 0 0 1.66E+07 1.90E+07 - - - 6.93 1 221125_WJC_METTL3_EV_vs_WT_F01.20414.20414.2 2.78E-06 13/22 R.VALDMTTLTIMR.Y "sp|P62333|PRS10_HUMAN,tr|A0A087X2I1|A0A087X2I1_HUMAN,tr|H0YJC0|H0YJC0_HUMAN,tr|H0YJS8|H0YJS8_HUMAN" 4 1363.7203 0.56 7866 20414 2 1363.718197 682.8674 26S proteasome regulatory subunit 10B OS=Homo sapiens OX=9606 GN=PSMC6 PE=1 SV=1 5.81 3770.4 - 1.77E+06 - - - -1.5736 - 2.529 0.59 - 732.9 1 2 0 -0.0021 12 0 0 0 1.65E+07 2.95E+07 - - - 5.8393 0.9979 221125_WJC_METTL3_EV_vs_WT_F01.20416.20416.2 0.0132 14-Oct K.FGFYEVFK.V "sp|Q00325|MPCP_HUMAN,tr|F8VWR4|F8VWR4_HUMAN,tr|F8VVM2|F8VVM2_HUMAN,tr|F8VWQ0|F8VWQ0_HUMAN" 4 1035.5066 0.66 7868 20416 2 1035.501975 518.7606 "Phosphate carrier protein, mitochondrial OS=Homo sapiens OX=9606 GN=SLC25A3 PE=1 SV=2" 6 3770.7 - 1.09E+06 - - - -4.4365 - 1.864 0.468 - 198.2 1 2 0 -0.0046 8 0 0 0 1.50E+07 2.26E+07 - - - 4.3743 0.9978 221125_WJC_METTL3_EV_vs_WT_F01.20418.20418.2 0.111 16-Sep R.FVC[160.03]PVILFK[136.11].G "sp|Q8NCE2|MTMRE_HUMAN,tr|B4DJ23|B4DJ23_HUMAN" 2 1129.6449 3.24 7870 20418 2 1129.643402 565.8297 Myotubularin-related protein 14 OS=Homo sapiens OX=9606 GN=MTMR14 PE=1 SV=2 8.22 3771 - 715863 - - - -1.3473 - 1.556 0.229 - 165.3 1 2 0 -0.0015 9 0 0 0 1.59E+07 4.90E+06 - - - 2.011 1 221125_WJC_METTL3_EV_vs_WT_F01.20424.20424.2 7.07E-08 17/34 R.IGPYQPNVPVGIDYVIPK[136.11].T "sp|P43243|MATR3_HUMAN,tr|B3KM87|B3KM87_HUMAN,tr|A8MXP9|A8MXP9_HUMAN,tr|A0A0R4J2E8|A0A0R4J2E8_HUMAN" 4 1976.0863 1.48 7874 20424 2 1976.080963 989.0504 Matrin-3 OS=Homo sapiens OX=9606 GN=MATR3 PE=1 SV=2 5.83 3771.7 - 1.56E+06 - - - -2.6755 - 2.758 0.616 - 505.6 1 2 0 -0.0053 18 0 0 0 1.67E+08 1.13E+08 - - - 6.0833 0.9841 221125_WJC_METTL3_EV_vs_WT_F01.20425.20425.2 0.00011 26-Nov R.IGPYQPNVPVGIDY.V "sp|P43243|MATR3_HUMAN,tr|B3KM87|B3KM87_HUMAN,tr|A8MXP9|A8MXP9_HUMAN,tr|A0A0R4J2E8|A0A0R4J2E8_HUMAN" 4 1530.7718 - 7875 20425 2 1530.769671 766.3932 Matrin-3 OS=Homo sapiens OX=9606 GN=MATR3 PE=1 SV=2 3.8 3771.8 - 1.44E+06 - - - -1.4202 - 1.749 0.511 - 281.2 1 1 0 -0.0022 14 0 0 0 - - - - - 4.2175 1 221125_WJC_METTL3_EV_vs_WT_F01.20426.20426.2 8.03E-09 17/34 R.IGPYQPNVPVGIDYVIPK.T "sp|P43243|MATR3_HUMAN,tr|B3KM87|B3KM87_HUMAN,tr|A8MXP9|A8MXP9_HUMAN,tr|A0A0R4J2E8|A0A0R4J2E8_HUMAN" 4 1968.072 1.48 7876 20426 2 1968.068328 985.0433 Matrin-3 OS=Homo sapiens OX=9606 GN=MATR3 PE=1 SV=2 5.83 3772 - 1.42E+06 - - - -1.8912 - 2.664 0.593 - 549.1 1 2 0 -0.0037 18 0 0 0 1.67E+08 1.13E+08 - - - 5.8287 0.9979 221125_WJC_METTL3_EV_vs_WT_F01.20429.20429.2 0.0598 14-Sep K.TFFLEALR[166.11].G "sp|Q9H0R4|HDHD2_HUMAN,tr|K7ER15|K7ER15_HUMAN" 2 1005.5523 0.63 7879 20429 2 1005.551144 503.7834 Haloacid dehalogenase-like hydrolase domain-containing protein 2 OS=Homo sapiens OX=9606 GN=HDHD2 PE=1 SV=1 5.66 3772.4 - 1.04E+06 - - - -1.1367 - 1.445 0.242 - 297.8 1 2 0 -0.0011 8 0 0 0 4.21E+06 6.68E+06 - - - 1.9383 0.9936 221125_WJC_METTL3_EV_vs_WT_F01.20431.20431.2 0.0192 22-Aug R.GLALALFGGEPK.N "sp|P49736|MCM2_HUMAN,tr|H0Y8E6|H0Y8E6_HUMAN" 2 1171.6601 2.05 7881 20431 2 1171.663846 586.8373 DNA replication licensing factor MCM2 OS=Homo sapiens OX=9606 GN=MCM2 PE=1 SV=4 6 3772.6 - 572558 - - - 3.1886 - 1.681 0.243 - 92.8 1 2 0 0.0037 12 0 0 0 2.15E+07 1.05E+07 - - - 2.2012 0.9988 221125_WJC_METTL3_EV_vs_WT_F01.20435.20435.2 0.158 14-Jul K.DTLGLFLR.E "sp|O75643|U520_HUMAN,tr|A0A494C1A5|A0A494C1A5_HUMAN" 2 933.5284 2.23 7883 20435 2 933.526679 467.7715 U5 small nuclear ribonucleoprotein 200 kDa helicase OS=Homo sapiens OX=9606 GN=SNRNP200 PE=1 SV=2 5.84 3773.1 - 1.01E+07 - - - -1.8082 - 1.593 0.318 - 201.8 1 2 0 -0.0017 8 0 0 0 1.12E+08 5.05E+07 - - - 2.7935 0.9988 221125_WJC_METTL3_EV_vs_WT_F01.20438.20438.2 0.00268 16-Sep R.YLDVSILGK[136.11].F sp|Q86U44|MTA70_HUMAN 1 1014.5841 0.25 7886 20438 2 1014.58198 508.2993 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 5.83 3773.5 - 892468 - - - -2.0876 - 1.634 0.339 - 173.2 1 2 0 -0.0021 9 0 0 0 6.14E+06 2.47E+07 - - - 2.9648 0.9988 221125_WJC_METTL3_EV_vs_WT_F01.20439.20439.2 0.00796 14-Aug K.TFFLEALR.G "sp|Q9H0R4|HDHD2_HUMAN,tr|K7ER15|K7ER15_HUMAN" 2 995.544 0.63 7887 20439 2 995.543082 498.7793 Haloacid dehalogenase-like hydrolase domain-containing protein 2 OS=Homo sapiens OX=9606 GN=HDHD2 PE=1 SV=1 5.66 3773.6 - 652636 - - - -0.9392 - 1.402 0.313 - 227.9 1 2 0 -0.0009 8 0 0 0 4.21E+06 6.68E+06 - - - 2.3716 0.9963 221125_WJC_METTL3_EV_vs_WT_F01.20440.20440.2 0.552 14-Jul R.ETILNLLR[166.11].K "sp|Q6P158|DHX57_HUMAN,tr|A0A087WZ11|A0A087WZ11_HUMAN" 2 980.5894 0.9 7888 20440 2 980.587311 491.302 Putative ATP-dependent RNA helicase DHX57 OS=Homo sapiens OX=9606 GN=DHX57 PE=1 SV=2 6.1 3773.7 - 530835 - - - -2.1314 - 1.73 0.175 - 154.8 1 2 0 -0.0021 8 0 0 0 3.84E+06 4.25E+06 - - - 1.986 0.966 221125_WJC_METTL3_EV_vs_WT_F01.20441.20441.2 0.00242 18-Sep K.IMLPWDPTGK.L "sp|P23396|RS3_HUMAN,tr|H0YEU2|H0YEU2_HUMAN,tr|E9PSF4|E9PSF4_HUMAN,tr|E9PL09|E9PL09_HUMAN,tr|E9PPU1|E9PPU1_HUMAN" 5 1156.5951 0.61 7889 20441 2 1156.5861 579.3048 40S ribosomal protein S3 OS=Homo sapiens OX=9606 GN=RPS3 PE=1 SV=2 5.84 3773.9 - 471784 - - - -7.7521 - 1.477 0.466 - 237 1 2 0 -0.009 10 0 0 0 1.62E+08 2.63E+08 - - - 3.5687 0.9974 221125_WJC_METTL3_EV_vs_WT_F01.20442.20442.2 0.0304 14-May K.ETLLAMFK[136.11].Y sp|P26639|SYTC_HUMAN 1 959.5241 0.67 7890 20442 2 959.52445 480.7693 "Threonine--tRNA ligase 1, cytoplasmic OS=Homo sapiens OX=9606 GN=TARS1 PE=1 SV=3" 6.1 3774 - 471146 - - - 0.3231 - 1.383 0.236 - 66.3 2 2 0 0.0003 8 0 0 0 5.59E+06 8.28E+06 - - - 1.6275 0.9067 221125_WJC_METTL3_EV_vs_WT_F01.20443.20443.2 0.25 20-Sep R.VTFLPTGITFK[136.11].S "sp|Q9Y624|JAM1_HUMAN,tr|A0A087WY82|A0A087WY82_HUMAN" 2 1230.7104 0.15 7891 20443 2 1230.71634 616.3625 Junctional adhesion molecule A OS=Homo sapiens OX=9606 GN=F11R PE=1 SV=1 8.72 3774.1 - 469152 - - - 4.8582 - 1.337 0.16 - 160.4 1 2 0 0.006 11 0 0 0 5.73E+06 3.72E+07 - - - 1.0066 0.9985 221125_WJC_METTL3_EV_vs_WT_F01.20445.20445.2 0.000849 22-Nov R.LAGATLLIFANK[136.11].Q sp|P36404|ARL2_HUMAN 1 1238.7478 0.18 7893 20445 2 1238.746615 620.3812 ADP-ribosylation factor-like protein 2 OS=Homo sapiens OX=9606 GN=ARL2 PE=1 SV=4 8.75 3774.4 - 376105 - - - -0.9639 - 1.665 0.239 - 252.6 1 2 0 -0.0012 12 0 0 0 4.99E+05 2.71E+06 - - - 2.1473 0.9589 221125_WJC_METTL3_EV_vs_WT_F01.20449.20449.2 0.298 12-Jun K.YPVWLWK.R "sp|Q13084|RM28_HUMAN,tr|A2IDC6|A2IDC6_HUMAN,tr|A2IDC7|A2IDC7_HUMAN,tr|Q4TT37|Q4TT37_HUMAN" 4 990.5327 1.29 7897 20449 2 990.528984 496.2736 "39S ribosomal protein L28, mitochondrial OS=Homo sapiens OX=9606 GN=MRPL28 PE=1 SV=4" 8.59 3774.9 - 254383 - - - -3.7757 - 1.09 0.235 - 95.2 1 2 0 -0.0037 7 0 0 0 4.57E+06 3.54E+06 - - - 1.0486 1 221125_WJC_METTL3_EV_vs_WT_F01.20453.20453.3 2.93E-07 14/68 R.IGPYQPNVPVGIDYVIPK.T "sp|P43243|MATR3_HUMAN,tr|B3KM87|B3KM87_HUMAN,tr|A8MXP9|A8MXP9_HUMAN,tr|A0A0R4J2E8|A0A0R4J2E8_HUMAN" 4 1968.072 1.44 7899 20453 3 1968.070871 657.0313 Matrin-3 OS=Homo sapiens OX=9606 GN=MATR3 PE=1 SV=2 5.83 3775.4 - 9.28E+06 - - - -0.5991 - 2.714 0.526 - 178.3 1 2 0 -0.0012 18 0 0 0 1.70E+08 1.18E+08 - - - 6.8902 0.9998 221125_WJC_METTL3_EV_vs_WT_F01.20454.20454.2 9.82E-07 18-Sep R.AFDLFNPNFK.S "sp|Q9Y3D9|RT23_HUMAN,tr|J3QLR8|J3QLR8_HUMAN" 2 1211.5975 1.2 7900 20454 2 1211.595998 606.806 "28S ribosomal protein S23, mitochondrial OS=Homo sapiens OX=9606 GN=MRPS23 PE=1 SV=2" 5.88 3775.4 - 4.63E+06 - - - -1.2471 - 1.987 0.532 - 241.5 1 2 0 -0.0015 10 0 0 0 6.63E+07 5.51E+07 - - - 4.8865 1 221125_WJC_METTL3_EV_vs_WT_F01.20455.20455.3 4.51E-06 16/68 R.IGPYQPNVPVGIDYVIPK[136.11].T "sp|P43243|MATR3_HUMAN,tr|B3KM87|B3KM87_HUMAN,tr|A8MXP9|A8MXP9_HUMAN,tr|A0A0R4J2E8|A0A0R4J2E8_HUMAN" 4 1976.0863 1.44 7901 20455 3 1976.083742 659.7027 Matrin-3 OS=Homo sapiens OX=9606 GN=MATR3 PE=1 SV=2 5.83 3775.5 - 6.35E+06 - - - -1.2692 - 2.711 0.491 - 280.8 1 2 0 -0.0025 18 0 0 0 1.70E+08 1.18E+08 - - - 6.4969 0.9998 221125_WJC_METTL3_EV_vs_WT_F01.20456.20456.2 1.46E-05 18-Nov R.AFDLFNPNFK[136.11].S "sp|Q9Y3D9|RT23_HUMAN,tr|J3QLR8|J3QLR8_HUMAN" 2 1219.6117 1.2 7902 20456 2 1219.608973 610.8131 "28S ribosomal protein S23, mitochondrial OS=Homo sapiens OX=9606 GN=MRPS23 PE=1 SV=2" 5.88 3775.5 - 4.34E+06 - - - -2.2433 - 2.041 0.578 - 391.4 1 2 0 -0.0027 10 0 0 0 6.63E+07 5.51E+07 - - - 5.3007 1 221125_WJC_METTL3_EV_vs_WT_F01.20458.20458.2 0.00188 16/24 K.ILESSQTLLSVLK.R "sp|O43805|SSNA1_HUMAN,tr|A0A087WV26|A0A087WV26_HUMAN" 2 1429.8392 2.31 7904 20458 2 1429.836215 715.9269 Sjoegren syndrome nuclear autoantigen 1 OS=Homo sapiens OX=9606 GN=SSNA1 PE=1 SV=2 6 3775.6 - 3.08E+06 - - - -2.0848 - 3.023 0.595 - 706.7 1 2 0 -0.003 13 0 0 0 8.71E+07 3.78E+07 - - - 6.274 0.9991 221125_WJC_METTL3_EV_vs_WT_F01.20459.20459.2 0.000144 18-Nov K.IMLPWDPTGK[136.11].L "sp|P23396|RS3_HUMAN,tr|H0YEU2|H0YEU2_HUMAN,tr|E9PSF4|E9PSF4_HUMAN,tr|E9PL09|E9PL09_HUMAN,tr|E9PPU1|E9PPU1_HUMAN" 5 1164.6093 0.61 7905 20459 2 1164.605784 583.3119 40S ribosomal protein S3 OS=Homo sapiens OX=9606 GN=RPS3 PE=1 SV=2 5.84 3775.7 - 3.01E+06 - - - -2.9898 - 1.925 0.423 - 430.6 1 2 0 -0.0035 10 0 0 0 1.62E+08 2.63E+08 - - - 3.9923 0.9999 221125_WJC_METTL3_EV_vs_WT_F01.20461.20461.3 3.40E-05 13/44 R.LFPPQWIC[160.03]C[160.03]DIR.Y sp|Q86U44|MTA70_HUMAN 1 1603.7639 0.02 7907 20461 3 1603.763372 535.5953 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 5.82 3775.8 - 1.93E+06 - - - -0.3542 - 2.036 0.458 - 216.5 1 2 0 -0.0006 12 0 0 0 4.73E+07 2.41E+09 - - - 5.6168 0.9999 221125_WJC_METTL3_EV_vs_WT_F01.20462.20462.2 7.22E-06 13/24 K.ILESSQTLLSVLK[136.11].R "sp|O43805|SSNA1_HUMAN,tr|A0A087WV26|A0A087WV26_HUMAN" 2 1437.8534 2.31 7908 20462 2 1437.851265 719.934 Sjoegren syndrome nuclear autoantigen 1 OS=Homo sapiens OX=9606 GN=SSNA1 PE=1 SV=2 6 3775.9 - 1.56E+06 - - - -1.4821 - 2.518 0.559 - 406.6 1 2 0 -0.0021 13 0 0 0 8.71E+07 3.78E+07 - - - 5.5392 0.9995 221125_WJC_METTL3_EV_vs_WT_F01.20471.20471.2 7.20E-07 14/32 R.LAALPENPPAIDWAYYK.A "sp|O75947|ATP5H_HUMAN,tr|F5H608|F5H608_HUMAN" 2 1930.9829 2.69 7917 20471 2 1930.976127 966.4987 "ATP synthase subunit d, mitochondrial OS=Homo sapiens OX=9606 GN=ATP5PD PE=1 SV=3" 4.37 3776.9 - 395860 - - - -3.5075 - 2.509 0.586 - 457.2 1 2 0 -0.0068 17 0 0 0 5.58E+06 2.07E+06 - - - 5.6286 0.9551 221125_WJC_METTL3_EV_vs_WT_F01.20472.20472.2 0.16 18-Oct H.ILELLTEVTR.R sp|P31944|CASPE_HUMAN 1 1185.6969 17.71 7918 20472 2 1185.694934 593.8557 Caspase-14 OS=Homo sapiens OX=9606 GN=CASP14 PE=1 SV=2 4.53 3777.1 - 342352 - - - -1.6488 - 2.07 0.276 - 314.7 1 1 0 -0.002 10 0 0 0 1.22E+07 6.90E+05 - - - 3.1097 0.9993 221125_WJC_METTL3_EV_vs_WT_F01.20476.20476.2 0.125 14-Sep R.VIFGLFGK[136.11].T "sp|P23284|PPIB_HUMAN,tr|A0A7P0Z497|A0A7P0Z497_HUMAN,tr|A0A7P0T7U3|A0A7P0T7U3_HUMAN,tr|A0A7P0TB45|A0A7P0TB45_HUMAN" 4 887.536 0.42 7920 20476 2 887.534343 444.7753 Peptidyl-prolyl cis-trans isomerase B OS=Homo sapiens OX=9606 GN=PPIB PE=1 SV=2 8.72 3777.5 - 6.79E+06 - - - -1.8951 - 1.737 0.357 - 248.5 1 2 0 -0.0017 8 0 0 0 4.37E+07 1.05E+08 - - - 3.3426 0.9987 221125_WJC_METTL3_EV_vs_WT_F01.20478.20478.2 0.0389 16-Oct K.TEILPPFFK[136.11].H sp|O75533|SF3B1_HUMAN 1 1098.6205 1.15 7922 20478 2 1098.617969 550.3175 Splicing factor 3B subunit 1 OS=Homo sapiens OX=9606 GN=SF3B1 PE=1 SV=3 5.66 3777.6 - 2.13E+06 - - - -2.2883 - 1.939 0.278 - 418.3 1 2 0 -0.0025 9 0 0 0 5.16E+07 4.48E+07 - - - 3.0092 0.9978 221125_WJC_METTL3_EV_vs_WT_F01.20479.20479.2 0.0402 26-Nov K.VTVNPGLLVPLDVK.L sp|Q6KB66|K2C80_HUMAN 1 1462.8759 999 7923 20479 2 1462.874526 732.4452 "Keratin, type II cytoskeletal 80 OS=Homo sapiens OX=9606 GN=KRT80 PE=1 SV=2" 5.81 3777.7 - 2.13E+06 - - - -0.9502 - 1.559 0.23 - 143.4 1 2 0 -0.0014 14 0 0 0 2.60E+07 0.00E+00 - - - 1.8537 0.9979 221125_WJC_METTL3_EV_vs_WT_F01.20480.20480.2 0.438 14-Jul R.VIFGLFGK.T "sp|P23284|PPIB_HUMAN,tr|A0A7P0Z497|A0A7P0Z497_HUMAN,tr|A0A7P0T7U3|A0A7P0T7U3_HUMAN,tr|A0A7P0TB45|A0A7P0TB45_HUMAN" 4 879.5218 0.42 7924 20480 2 879.520231 440.7682 Peptidyl-prolyl cis-trans isomerase B OS=Homo sapiens OX=9606 GN=PPIB PE=1 SV=2 8.72 3777.8 - 1.96E+06 - - - -1.8123 - 1.174 0.372 - 129.3 1 2 0 -0.0016 8 0 0 0 4.37E+07 1.05E+08 - - - 2.2719 0.9998 221125_WJC_METTL3_EV_vs_WT_F01.20481.20481.2 0.000885 16-Oct R.YLTVAAIFR.G "sp|Q9BVA1|TBB2B_HUMAN,sp|A6NNZ2|TBB8B_HUMAN,sp|Q13885|TBB2A_HUMAN" 3 1052.6019 0.76 7925 20481 2 1052.600829 527.3082 Tubulin beta-2B chain OS=Homo sapiens OX=9606 GN=TUBB2B PE=1 SV=1 8.75 3777.9 - 1.66E+06 - - - -0.9852 - 2.04 0.456 - 361.5 1 2 0 -0.001 9 0 0 0 1.43E+07 1.87E+07 - - - 4.4713 0.9999 221125_WJC_METTL3_EV_vs_WT_F01.20484.20484.2 6.96E-05 16-Oct R.FYNLVLLPR[166.11].V "sp|Q13895|BYST_HUMAN,tr|H7BY94|H7BY94_HUMAN" 2 1143.668 0.85 7928 20484 2 1143.667544 572.8413 Bystin OS=Homo sapiens OX=9606 GN=BYSL PE=1 SV=3 8.75 3778.2 - 1.04E+06 - - - -0.3865 - 2.008 0.475 - 410.4 1 2 0 -0.0004 9 0 0 0 2.59E+07 3.06E+07 - - - 4.5661 0.9994 221125_WJC_METTL3_EV_vs_WT_F01.20485.20485.2 0.000111 20-Dec K.ILLTQENPFFR.K sp|Q08J23|NSUN2_HUMAN 1 1376.7452 1.05 7929 20485 2 1376.741044 689.3799 RNA cytosine C(5)-methyltransferase NSUN2 OS=Homo sapiens OX=9606 GN=NSUN2 PE=1 SV=2 6 3778.4 - 813388 - - - -3.0449 - 2.144 0.489 - 502.8 1 2 0 -0.0042 11 0 0 0 7.10E+07 6.79E+07 - - - 4.7146 0.9837 221125_WJC_METTL3_EV_vs_WT_F01.20486.20486.2 0.0356 14-Jul K.DFLPIEIR.G sp|Q5VT06|CE350_HUMAN 1 1001.5546 1.53 7930 20486 2 1001.551163 501.7846 Centrosome-associated protein 350 OS=Homo sapiens OX=9606 GN=CEP350 PE=1 SV=1 4.37 3778.5 - 757010 - - - -3.4137 - 1.558 0.159 - 198.3 1 2 0 -0.0034 8 0 0 0 9.06E+06 5.91E+06 - - - 1.5516 0.9841 221125_WJC_METTL3_EV_vs_WT_F01.20489.20489.2 8.12E-07 18-Nov L.C[160.03]FVYPLDFAR[166.11].T "sp|P12235|ADT1_HUMAN,sp|P05141|ADT2_HUMAN,sp|P12236|ADT3_HUMAN,tr|V9GYG0|V9GYG0_HUMAN" 4 1296.62 0.81 7933 20489 2 1296.617141 649.3173 ADP\ATP translocase 1 OS=Homo sapiens OX=9606 GN=SLC25A4 PE=1 SV=4 5.83 3778.9 - 586228 - - - -2.2428 - 2.173 0.53 - 529 1 1 0 -0.0029 10 0 0 0 2.99E+06 3.71E+06 - - - 5.121 0.9999 221125_WJC_METTL3_EV_vs_WT_F01.20490.20490.3 4.86E-06 13/52 K.VTVNPGLLVPLDVK.L sp|Q6KB66|K2C80_HUMAN 1 1462.8759 1.2 7934 20490 3 1462.874542 488.6326 "Keratin, type II cytoskeletal 80 OS=Homo sapiens OX=9606 GN=KRT80 PE=1 SV=2" 5.81 3779 - 569032 - - - -0.9392 - 2.376 0.422 - 226.6 1 2 0 -0.0014 14 0 0 0 4.19E+06 3.49E+06 - - - 5.5444 0.9994 221125_WJC_METTL3_EV_vs_WT_F01.20493.20493.2 0.00152 24-Sep R.AVEYLLMGIPGDR[166.11].E sp|P54727|RD23B_HUMAN 1 1442.7467 0.73 7937 20493 2 1442.746276 722.3806 UV excision repair protein RAD23 homolog B OS=Homo sapiens OX=9606 GN=RAD23B PE=1 SV=1 4.37 3779.4 - 838041 - - - -0.298 - 1.671 0.341 - 220.8 1 2 0 -0.0004 13 0 0 0 2.16E+06 2.97E+06 - - - 2.8772 0.999 221125_WJC_METTL3_EV_vs_WT_F01.20496.20496.2 0.0405 22-Dec K.IGLIQFC[160.03]LSAPK[136.11].T sp|P50991|TCPD_HUMAN 1 1353.757 0.59 7938 20496 2 1353.755742 677.8858 T-complex protein 1 subunit delta OS=Homo sapiens OX=9606 GN=CCT4 PE=1 SV=4 8.22 3779.8 - 3.04E+06 - - - -0.9248 - 1.656 0.293 - 311 1 2 0 -0.0013 12 0 0 0 2.78E+07 4.75E+07 - - - 2.5319 0.9999 221125_WJC_METTL3_EV_vs_WT_F01.20497.20497.2 0.00962 20-Nov K.ILLTQENPFFR[166.11].K sp|Q08J23|NSUN2_HUMAN 1 1386.7535 1.05 7939 20497 2 1386.751889 694.384 RNA cytosine C(5)-methyltransferase NSUN2 OS=Homo sapiens OX=9606 GN=NSUN2 PE=1 SV=2 6 3779.9 - 2.54E+06 - - - -1.166 - 2.411 0.534 - 465.4 1 2 0 -0.0016 11 0 0 0 7.10E+07 6.79E+07 - - - 5.3653 0.9997 221125_WJC_METTL3_EV_vs_WT_F01.20498.20498.2 2.85E-08 24-Nov K.MLVLDEADEMLNK[136.11].G "sp|P38919|IF4A3_HUMAN,tr|I3L3H2|I3L3H2_HUMAN" 2 1527.7404 1.6 7940 20498 2 1527.736627 764.8775 Eukaryotic initiation factor 4A-III OS=Homo sapiens OX=9606 GN=EIF4A3 PE=1 SV=4 3.92 3779.9 - 3.06E+06 - - - -2.4808 - 2.553 0.538 - 282.6 1 2 0 -0.0038 13 0 0 0 6.24E+07 3.90E+07 - - - 5.419 0.9995 221125_WJC_METTL3_EV_vs_WT_F01.20499.20499.2 5.51E-07 18-Oct K.FSDFLLDPYK[136.11].Y sp|Q9UIG0|BAZ1B_HUMAN 1 1251.6267 0.76 7941 20499 2 1251.625607 626.8206 Tyrosine-protein kinase BAZ1B OS=Homo sapiens OX=9606 GN=BAZ1B PE=1 SV=2 4.21 3780 - 1.03E+06 - - - -0.8661 - 2 0.308 - 254.8 1 2 0 -0.0011 10 0 0 0 8.51E+06 1.11E+07 - - - 3.2503 0.9999 221125_WJC_METTL3_EV_vs_WT_F01.20500.20500.3 0.000932 Oct-48 K.ILESSQTLLSVLK.R "sp|O43805|SSNA1_HUMAN,tr|A0A087WV26|A0A087WV26_HUMAN" 2 1429.8392 3.86 7942 20500 3 1429.83685 477.6203 Sjoegren syndrome nuclear autoantigen 1 OS=Homo sapiens OX=9606 GN=SSNA1 PE=1 SV=2 6 3780.1 - 1.00E+06 - - - -1.6407 - 2.252 0.415 - 186.2 1 2 0 -0.0023 13 0 0 0 7.06E+06 1.83E+06 - - - 5.3673 0.9997 221125_WJC_METTL3_EV_vs_WT_F01.20502.20502.2 2.20E-05 18-Nov K.FSDFLLDPYK.Y sp|Q9UIG0|BAZ1B_HUMAN 1 1243.6125 0.76 7944 20502 2 1243.610951 622.8135 Tyrosine-protein kinase BAZ1B OS=Homo sapiens OX=9606 GN=BAZ1B PE=1 SV=2 4.21 3780.3 - 922953 - - - -1.2383 - 1.618 0.478 - 292.8 1 2 0 -0.0015 10 0 0 0 8.51E+06 1.11E+07 - - - 3.9142 0.9999 221125_WJC_METTL3_EV_vs_WT_F01.20503.20503.2 3.29E-05 13/20 K.IFGVTTLDIVR.A "sp|P40926|MDHM_HUMAN,tr|G3XAL0|G3XAL0_HUMAN" 2 1232.7129 1.54 7945 20503 2 1232.711619 617.3637 "Malate dehydrogenase, mitochondrial OS=Homo sapiens OX=9606 GN=MDH2 PE=1 SV=3" 5.84 3780.4 - 912356 - - - -1.0173 - 2.323 0.483 - 640 1 2 0 -0.0013 11 0 0 0 4.22E+07 2.74E+07 - - - 4.8882 0.9998 221125_WJC_METTL3_EV_vs_WT_F01.20504.20504.2 0.00327 20-Dec K.LALDIEIATYR.K "sp|P14136|GFAP_HUMAN,sp|Q6KB66|K2C80_HUMAN,sp|P05787|K2C8_HUMAN,sp|P19013|K2C4_HUMAN,sp|P04264|K2C1_HUMAN,sp|P08729|K2C7_HUMAN,tr|A0A1W2PR46|A0A1W2PR46_HUMAN,tr|A0A1X7SBR3|A0A1X7SBR3_HUMAN,tr|A0A1W2PQU7|A0A1W2PQU7_HUMAN,tr|K7EJU1|K7EJU1_HUMAN,tr|A0A1X7SCE1|A0A1X7SCE1_HUMAN,tr|A0A1W2PRT3|A0A1W2PRT3_HUMAN,tr|A0A1W2PS58|A0A1W2PS58_HUMAN,tr|K7EPI4|K7EPI4_HUMAN" 14 1276.7027 3.53 7946 20504 2 1276.70192 639.3586 Glial fibrillary acidic protein OS=Homo sapiens OX=9606 GN=GFAP PE=1 SV=1 4.37 3780.6 - 734715 - - - -0.6133 - 2.744 0.354 - 703 1 2 0 -0.0008 11 0 0 0 2.58E+07 7.30E+06 - - - 4.3861 0.9955 221125_WJC_METTL3_EV_vs_WT_F01.20506.20506.2 0.582 12-Jul R.LGFDLFK.E "sp|Q9UIV8|SPB13_HUMAN,tr|F8WE70|F8WE70_HUMAN,tr|C9JL93|C9JL93_HUMAN,tr|A0A0A0MQW3|A0A0A0MQW3_HUMAN" 4 838.4589 31.09 7948 20506 2 838.457612 420.2367 Serpin B13 OS=Homo sapiens OX=9606 GN=SERPINB13 PE=1 SV=2 5.84 3780.8 - 391270 - - - -1.5242 - 1.583 0.138 - 104.7 1 2 0 -0.0013 7 0 0 0 5.54E+06 1.78E+05 - - - 1.5153 0.9998 221125_WJC_METTL3_EV_vs_WT_F01.20507.20507.2 0.000172 15/26 K.IPVTIITGYLGAGK.T "sp|Q5RIA9|CBWD5_HUMAN,sp|Q9BRT8|CBWD1_HUMAN,sp|Q5JTY5|CBWD3_HUMAN,sp|Q4V339|CBWD6_HUMAN,sp|Q8IUF1|CBWD2_HUMAN,tr|A0A087WZQ3|A0A087WZQ3_HUMAN,tr|Q5JTY2|Q5JTY2_HUMAN,tr|Q6NVZ8|Q6NVZ8_HUMAN,tr|A0A0B4J2E3|A0A0B4J2E3_HUMAN,tr|A0A087X140|A0A087X140_HUMAN,tr|F8WEU0|F8WEU0_HUMAN,tr|E7EUZ7|E7EUZ7_HUMAN,tr|F8WEG4|F8WEG4_HUMAN,tr|A0A087WYD2|A0A087WYD2_HUMAN,tr|A0A0A0MRU4|A0A0A0MRU4_HUMAN,tr|Q5RIB0|Q5RIB0_HUMAN,tr|H0Y5V3|H0Y5V3_HUMAN,tr|A0A0A6YYH9|A0A0A6YYH9_HUMAN,tr|A0A087WWG3|A0A087WWG3_HUMAN,tr|A0A087WTC0|A0A087WTC0_HUMAN,tr|C9J3G2|C9J3G2_HUMAN,tr|F2Z2T4|F2Z2T4_HUMAN,tr|Q5RIB5|Q5RIB5_HUMAN" 23 1401.8232 0.87 7949 20507 2 1401.820498 701.9189 COBW domain-containing protein 5 OS=Homo sapiens OX=9606 GN=CBWD5 PE=2 SV=1 8.59 3780.9 - 352645 - - - -1.8932 - 2.821 0.487 - 924.5 1 2 0 -0.0027 14 0 0 0 3.81E+06 4.38E+06 - - - 5.2397 0.9998 221125_WJC_METTL3_EV_vs_WT_F01.20512.20512.2 2.32E-05 16-Nov R.FYNLVLLPR.V "sp|Q13895|BYST_HUMAN,tr|H7BY94|H7BY94_HUMAN" 2 1133.6597 0.85 7952 20512 2 1133.657959 567.8371 Bystin OS=Homo sapiens OX=9606 GN=BYSL PE=1 SV=3 8.75 3781.6 - 3.28E+06 - - - -1.5498 - 2.226 0.513 - 568.4 1 2 0 -0.0018 9 0 0 0 2.59E+07 3.06E+07 - - - 5.1445 0.9998 221125_WJC_METTL3_EV_vs_WT_F01.20514.20514.2 6.65E-05 20-Dec K.IFGVTTLDIVR[166.11].A "sp|P40926|MDHM_HUMAN,tr|G3XAL0|G3XAL0_HUMAN" 2 1242.7211 1.53 7954 20514 2 1242.719024 622.3678 "Malate dehydrogenase, mitochondrial OS=Homo sapiens OX=9606 GN=MDH2 PE=1 SV=3" 5.84 3781.7 - 3.42E+06 - - - -1.7051 - 2.113 0.489 - 483.3 1 2 0 -0.0021 11 0 0 0 4.19E+07 2.74E+07 - - - 4.6759 0.9996 221125_WJC_METTL3_EV_vs_WT_F01.20515.20515.2 3.78E-07 22-Oct K.LVGQSIIAYLQK[136.11].K "sp|P53621|COPA_HUMAN,tr|A0A3B3IU89|A0A3B3IU89_HUMAN,tr|A0A3B3IT15|A0A3B3IT15_HUMAN" 3 1339.7955 0.08 7955 20515 2 1339.791854 670.905 Coatomer subunit alpha OS=Homo sapiens OX=9606 GN=COPA PE=1 SV=2 8.59 3781.9 - 1.44E+06 - - - -2.7116 - 2.243 0.536 - 264.2 1 2 0 -0.0036 12 0 0 0 5.09E+05 6.69E+06 - - - 5.1243 1 221125_WJC_METTL3_EV_vs_WT_F01.20516.20516.2 1.66E-06 16/28 K.LLGASELPIVTPALR[166.11].A "sp|P52292|IMA1_HUMAN,tr|A0A7I2V3Z3|A0A7I2V3Z3_HUMAN,tr|A0A7I2YQE1|A0A7I2YQE1_HUMAN,tr|A0A7I2V487|A0A7I2V487_HUMAN,tr|A0A7I2V351|A0A7I2V351_HUMAN" 5 1558.9322 1.24 7956 20516 2 1558.932496 780.4734 Importin subunit alpha-1 OS=Homo sapiens OX=9606 GN=KPNA2 PE=1 SV=1 6 3782 - 1.25E+06 - - - 0.1905 - 3.432 0.577 - 565.3 1 2 0 0.0003 15 0 0 0 1.87E+08 1.51E+08 - - - 6.3344 0.9998 221125_WJC_METTL3_EV_vs_WT_F01.20517.20517.2 1.01E-05 16-Oct K.VSFLLPTLR.K "sp|Q9UFC0|LRWD1_HUMAN,tr|H7C5S6|H7C5S6_HUMAN" 2 1044.6332 1.04 7957 20517 2 1044.632021 523.3239 Leucine-rich repeat and WD repeat-containing protein 1 OS=Homo sapiens OX=9606 GN=LRWD1 PE=1 SV=2 9.72 3782.1 - 1.16E+06 - - - -1.097 - 1.729 0.488 - 349 1 2 0 -0.0011 9 0 0 0 1.38E+07 1.33E+07 - - - 4.2291 0.8832 221125_WJC_METTL3_EV_vs_WT_F01.20518.20518.2 0.0115 14-Jul R.K[136.11]MC[160.03]LFAGF.Q "sp|Q00839|HNRPU_HUMAN,tr|A0A1W2PQL0|A0A1W2PQL0_HUMAN,tr|A0A1W2PPL4|A0A1W2PPL4_HUMAN,tr|A0A1W2PQ74|A0A1W2PQ74_HUMAN,tr|Q5RI18|Q5RI18_HUMAN,tr|A0A1W2PP35|A0A1W2PP35_HUMAN,tr|A0A1W2PPS1|A0A1W2PPS1_HUMAN,tr|A0A1W2PRZ7|A0A1W2PRZ7_HUMAN,tr|A0A1W2PPH7|A0A1W2PPH7_HUMAN,tr|A0A1W2PQD4|A0A1W2PQD4_HUMAN,tr|A0A1W2PP34|A0A1W2PP34_HUMAN,tr|A0A1X7SBS1|A0A1X7SBS1_HUMAN" 12 980.4703 0.96 7958 20518 2 980.468798 491.2424 Heterogeneous nuclear ribonucleoprotein U OS=Homo sapiens OX=9606 GN=HNRNPU PE=1 SV=6 8.22 3782.2 - 862122 - - - -1.5625 - 1.219 0.334 - 166.6 1 1 0 -0.0015 8 0 0 0 1.09E+07 1.13E+07 - - - 2.1047 0.8976 221125_WJC_METTL3_EV_vs_WT_F01.20519.20519.2 0.0087 14-Jun R.IILLFDAH.K "sp|Q9H223|EHD4_HUMAN,sp|Q9NZN3|EHD3_HUMAN,sp|Q9H4M9|EHD1_HUMAN,tr|C9JC03|C9JC03_HUMAN,tr|C9J2Z4|C9J2Z4_HUMAN,tr|C9JDQ8|C9JDQ8_HUMAN,tr|A0A024R571|A0A024R571_HUMAN" 7 940.5382 - 7959 20519 2 940.535891 471.2764 EH domain-containing protein 4 OS=Homo sapiens OX=9606 GN=EHD4 PE=1 SV=1 5.08 3782.4 - 832425 - - - -2.4582 - 1.476 0.349 - 86.9 1 1 0 -0.0023 8 0 0 0 - - - - - 2.7922 0.9988 221125_WJC_METTL3_EV_vs_WT_F01.20528.20528.2 0.0295 14-Sep R.LDTIFFAK.Q "sp|Q9Y5K5|UCHL5_HUMAN,tr|Q5LJA9|Q5LJA9_HUMAN,tr|Q5LJB0|Q5LJB0_HUMAN,tr|Q5LJA5|Q5LJA5_HUMAN" 4 953.5222 1.82 7966 20528 2 953.51991 477.7684 Ubiquitin carboxyl-terminal hydrolase isozyme L5 OS=Homo sapiens OX=9606 GN=UCHL5 PE=1 SV=3 5.84 3783.4 - 510361 - - - -2.4215 - 2.004 0.277 - 211.4 1 2 0 -0.0023 8 0 0 0 3.35E+06 1.84E+06 - - - 3.1827 0.95 221125_WJC_METTL3_EV_vs_WT_F01.20530.20530.2 0.000771 14-Sep R.KMC[160.03]LFAGF.Q "sp|Q00839|HNRPU_HUMAN,tr|A0A1W2PQL0|A0A1W2PQL0_HUMAN,tr|A0A1W2PPL4|A0A1W2PPL4_HUMAN,tr|A0A1W2PQ74|A0A1W2PQ74_HUMAN,tr|Q5RI18|Q5RI18_HUMAN,tr|A0A1W2PP35|A0A1W2PP35_HUMAN,tr|A0A1W2PPS1|A0A1W2PPS1_HUMAN,tr|A0A1W2PRZ7|A0A1W2PRZ7_HUMAN,tr|A0A1W2PPH7|A0A1W2PPH7_HUMAN,tr|A0A1W2PQD4|A0A1W2PQD4_HUMAN,tr|A0A1W2PP34|A0A1W2PP34_HUMAN,tr|A0A1X7SBS1|A0A1X7SBS1_HUMAN" 12 972.4561 0.96 7968 20530 2 972.454639 487.2353 Heterogeneous nuclear ribonucleoprotein U OS=Homo sapiens OX=9606 GN=HNRNPU PE=1 SV=6 8.22 3783.6 - 1.21E+06 - - - -1.5332 - 1.489 0.363 - 284.6 1 1 0 -0.0015 8 0 0 0 1.09E+07 1.13E+07 - - - 2.9223 0.9998 221125_WJC_METTL3_EV_vs_WT_F01.20532.20532.2 2.22E-06 20-Nov K.WYLENVYPELR.V sp|Q10471|GALT2_HUMAN 1 1480.7351 1.64 7970 20532 2 1480.732541 741.3748 Polypeptide N-acetylgalactosaminyltransferase 2 OS=Homo sapiens OX=9606 GN=GALNT2 PE=1 SV=1 4.53 3783.9 - 707489 - - - -1.7046 - 2.169 0.497 - 559.4 1 2 0 -0.0025 11 0 0 0 3.94E+07 2.40E+07 - - - 4.8056 0.9999 221125_WJC_METTL3_EV_vs_WT_F01.20533.20533.2 1.11E-05 15/22 R.VPFLVLEC[160.03]PNLK[136.11].L "sp|Q9NRP0|OSTC_HUMAN,tr|A0A087WUD3|A0A087WUD3_HUMAN" 2 1435.7989 0.64 7971 20533 2 1435.798968 718.9067 Oligosaccharyltransferase complex subunit OSTC OS=Homo sapiens OX=9606 GN=OSTC PE=1 SV=1 5.97 3784 - 690754 - - - 0.0766 - 2.611 0.537 - 852.3 1 2 0 0.0001 12 0 0 0 4.72E+06 7.35E+06 - - - 5.5325 0.9998 221125_WJC_METTL3_EV_vs_WT_F01.20535.20535.2 0.000287 26-Nov K.IEEVLSGVLDTELR.Y "sp|P18583|SON_HUMAN,tr|J3QSZ5|J3QSZ5_HUMAN" 2 1571.8407 2.47 7973 20535 2 1571.837947 786.9276 Protein SON OS=Homo sapiens OX=9606 GN=SON PE=1 SV=4 4 3784.3 - 469025 - - - -1.7215 - 2.495 0.504 - 480 1 2 0 -0.0027 14 0 0 0 7.06E+06 2.86E+06 - - - 5.0571 0.9999 221125_WJC_METTL3_EV_vs_WT_F01.20537.20537.2 1.91E-06 22-Oct R.YGLFPANYVELR[166.11].Q sp|Q14247|SRC8_HUMAN 1 1450.7484 0.58 7975 20537 2 1450.748314 726.3815 Src substrate cortactin OS=Homo sapiens OX=9606 GN=CTTN PE=1 SV=2 6 3784.5 - 293598 - - - -0.0738 - 2.123 0.584 - 340.1 1 2 0 -0.0001 12 0 0 0 6.40E+06 1.11E+07 - - - 5.3352 0.9768 221125_WJC_METTL3_EV_vs_WT_F01.20538.20538.3 2.49E-05 Dec-36 F.PPQWIC[160.03]C[160.03]DIR[166.11].Y sp|Q86U44|MTA70_HUMAN 1 1353.6197 0.001 7976 20538 3 1353.614686 452.2139 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 6.18 3784.6 - 281858 - - - -3.7278 - 2.047 0.509 - 280.4 1 1 0 -0.005 10 0 0 0 0.00E+00 1.99E+06 - - - 6.3056 0.9997 221125_WJC_METTL3_EV_vs_WT_F01.20541.20541.2 3.23E-05 24-Aug K.MLVLDEADEMLNK.G "sp|P38919|IF4A3_HUMAN,tr|I3L3H2|I3L3H2_HUMAN" 2 1519.7262 1.6 7978 20541 2 1519.722445 760.8704 Eukaryotic initiation factor 4A-III OS=Homo sapiens OX=9606 GN=EIF4A3 PE=1 SV=4 3.92 3785 - 1.81E+06 - - - -2.482 - 2.11 0.61 - 142.1 1 2 0 -0.0038 13 0 0 0 6.24E+07 3.90E+07 - - - 5.4617 0.9999 221125_WJC_METTL3_EV_vs_WT_F01.20543.20543.2 1.88E-06 22-Dec K.GIDPFSLDALSK[136.11].E sp|P40227|TCPZ_HUMAN 1 1269.6696 0.5 7980 20543 2 1269.668242 635.8421 T-complex protein 1 subunit zeta OS=Homo sapiens OX=9606 GN=CCT6A PE=1 SV=3 4.21 3785.2 - 5.05E+06 - - - -1.0837 - 2.422 0.51 - 401.5 1 2 0 -0.0014 12 0 0 0 4.13E+08 8.28E+08 - - - 5.1349 1 221125_WJC_METTL3_EV_vs_WT_F01.20545.20545.2 1.18E-08 14/28 K.LLGASELPIVTPALR.A "sp|P52292|IMA1_HUMAN,tr|A0A7I2V3Z3|A0A7I2V3Z3_HUMAN,tr|A0A7I2YQE1|A0A7I2YQE1_HUMAN,tr|A0A7I2V487|A0A7I2V487_HUMAN,tr|A0A7I2V351|A0A7I2V351_HUMAN" 5 1548.9239 1.24 7982 20545 2 1548.923081 775.4692 Importin subunit alpha-1 OS=Homo sapiens OX=9606 GN=KPNA2 PE=1 SV=1 6 3785.3 - 2.85E+06 - - - -0.5475 - 3.08 0.552 - 370 1 2 0 -0.0008 15 0 0 0 1.87E+08 1.51E+08 - - - 5.8835 0.9997 221125_WJC_METTL3_EV_vs_WT_F01.20546.20546.2 0.00584 16-Aug R.ELFGPELFR.L "sp|P35249|RFC4_HUMAN,tr|C9JXZ7|C9JXZ7_HUMAN,tr|C9J8M3|C9J8M3_HUMAN,tr|C9JZI1|C9JZI1_HUMAN" 4 1106.576 1.08 7983 20546 2 1106.575617 554.2953 Replication factor C subunit 4 OS=Homo sapiens OX=9606 GN=RFC4 PE=1 SV=2 4.53 3785.4 - 1.47E+06 - - - -0.3877 - 1.624 0.422 - 180.2 1 2 0 -0.0004 9 0 0 0 1.93E+07 1.79E+07 - - - 3.5606 0.9993 221125_WJC_METTL3_EV_vs_WT_F01.20547.20547.2 0.0214 20-Dec K.FLFVDADQIVR[166.11].T sp|Q9NYU2|UGGG1_HUMAN 1 1331.7113 0.09 7984 20547 2 1331.707672 666.8629 UDP-glucose:glycoprotein glucosyltransferase 1 OS=Homo sapiens OX=9606 GN=UGGT1 PE=1 SV=3 4.21 3785.5 - 1.31E+06 - - - -2.7296 - 2.299 0.388 - 477.9 1 2 0 -0.0036 11 0 0 0 1.82E+06 2.13E+07 - - - 4.1577 0.9999 221125_WJC_METTL3_EV_vs_WT_F01.20548.20548.3 1.55E-06 17/56 K.LLGASELPIVTPALR[166.11].A "sp|P52292|IMA1_HUMAN,tr|A0A7I2V3Z3|A0A7I2V3Z3_HUMAN,tr|A0A7I2YQE1|A0A7I2YQE1_HUMAN,tr|A0A7I2V487|A0A7I2V487_HUMAN,tr|A0A7I2V351|A0A7I2V351_HUMAN" 5 1558.9322 1.31 7985 20548 3 1558.927587 520.6513 Importin subunit alpha-1 OS=Homo sapiens OX=9606 GN=KPNA2 PE=1 SV=1 6 3785.6 - 655172 - - - -2.9584 - 2.723 0.535 - 444.9 1 2 0 -0.0046 15 0 0 0 3.61E+07 2.76E+07 - - - 7.1173 0.9959 221125_WJC_METTL3_EV_vs_WT_F01.20549.20549.2 0.0692 14-Jun K.LFGLPNDS.- "sp|Q96J01|THOC3_HUMAN,tr|D6REC9|D6REC9_HUMAN" 2 861.4232 - 7986 20549 2 861.422991 431.7189 THO complex subunit 3 OS=Homo sapiens OX=9606 GN=THOC3 PE=1 SV=1 3.8 3785.8 - 590330 - - - -0.2809 - 1.2 0.224 - 103.1 1 2 0 -0.0002 8 0 0 0 - - - - - 1.2453 0.9998 221125_WJC_METTL3_EV_vs_WT_F01.20550.20550.2 1.52E-05 24-Oct R.VLLISGFPVQVC[160.03]K.A "sp|Q9Y2W6|TDRKH_HUMAN,tr|F6TB26|F6TB26_HUMAN,tr|E9PKN8|E9PKN8_HUMAN,tr|Q5SZR4|Q5SZR4_HUMAN" 4 1458.8269 1.64 7987 20550 2 1458.824152 730.4207 Tudor and KH domain-containing protein OS=Homo sapiens OX=9606 GN=TDRKH PE=1 SV=2 8.19 3785.9 - 435149 - - - -1.8549 - 2.219 0.506 - 321.7 1 2 0 -0.0027 13 0 0 0 8.48E+06 5.17E+06 - - - 4.8231 0.9998 221125_WJC_METTL3_EV_vs_WT_F01.20551.20551.2 7.03E-06 Oct-32 R.ALIVVPYAEGVIPDEAK.A "sp|Q05519|SRS11_HUMAN,tr|Q5T760|Q5T760_HUMAN" 2 1782.9768 7.87 7988 20551 2 1782.974964 892.4957 Serine\arginine-rich splicing factor 11 OS=Homo sapiens OX=9606 GN=SRSF11 PE=1 SV=1 4.14 3786.1 - 395267 - - - -1.0028 - 2.129 0.5 - 190 1 2 0 -0.0018 17 0 0 0 2.87E+06 3.64E+05 - - - 4.5912 1 221125_WJC_METTL3_EV_vs_WT_F01.20553.20553.2 2.39E-08 22-Dec K.GIDPFSLDALSK.E sp|P40227|TCPZ_HUMAN 1 1261.6554 0.5 7989 20553 2 1261.654028 631.835 T-complex protein 1 subunit zeta OS=Homo sapiens OX=9606 GN=CCT6A PE=1 SV=3 4.21 3786.3 - 7.16E+06 - - - -1.1017 - 2.481 0.601 - 453.6 1 2 0 -0.0014 12 0 0 0 4.14E+08 8.28E+08 - - - 5.8704 0.9997 221125_WJC_METTL3_EV_vs_WT_F01.20555.20555.2 0.00702 16-Sep R.GFAFVYFER[166.11].L sp|Q13595|TRA2A_HUMAN 1 1144.5581 1.5 7990 20555 2 1144.557569 573.2863 Transformer-2 protein homolog alpha OS=Homo sapiens OX=9606 GN=TRA2A PE=1 SV=1 6 3786.5 - 2.86E+06 - - - -0.4648 - 1.851 0.386 - 394.7 1 2 0 -0.0005 9 0 0 0 2.48E+07 1.66E+07 - - - 3.6732 0.9987 221125_WJC_METTL3_EV_vs_WT_F01.20556.20556.2 0.000481 18-Sep K.DLIGVQNLLK[136.11].K "sp|Q13813|SPTN1_HUMAN,tr|A0A0D9SF54|A0A0D9SF54_HUMAN,tr|A0A0D9SGF6|A0A0D9SGF6_HUMAN" 3 1119.6743 1.54 7991 20556 2 1119.67186 560.8444 "Spectrin alpha chain, non-erythrocytic 1 OS=Homo sapiens OX=9606 GN=SPTAN1 PE=1 SV=3" 5.84 3786.6 - 1.74E+06 - - - -2.1881 - 1.776 0.314 - 162.7 1 2 0 -0.0024 10 0 0 0 1.41E+07 9.12E+06 - - - 2.9627 0.9998 221125_WJC_METTL3_EV_vs_WT_F01.20558.20558.2 0.000156 22-Dec R.FLPEFPSC[160.03]SLLK.E sp|Q9H9A6|LRC40_HUMAN 1 1436.7374 1.26 7993 20558 2 1436.735926 719.376 Leucine-rich repeat-containing protein 40 OS=Homo sapiens OX=9606 GN=LRRC40 PE=1 SV=1 5.99 3786.7 - 2.11E+06 - - - -1.0078 - 2.213 0.452 - 416.8 1 2 0 -0.0014 12 0 0 0 2.08E+07 1.65E+07 - - - 4.4691 1 221125_WJC_METTL3_EV_vs_WT_F01.20559.20559.2 2.04E-07 14/22 R.VPDGMVGLIIGR.G "sp|Q92945|FUBP2_HUMAN,tr|M0QYH3|M0QYH3_HUMAN,tr|M0R0C6|M0R0C6_HUMAN,tr|M0QXW7|M0QXW7_HUMAN,tr|A0A087WTP3|A0A087WTP3_HUMAN" 5 1225.6853 1.44 7994 20559 2 1225.682869 613.8499 Far upstream element-binding protein 2 OS=Homo sapiens OX=9606 GN=KHSRP PE=1 SV=4 5.81 3786.9 - 1.69E+06 - - - -1.9654 - 2.468 0.627 - 811.7 1 2 0 -0.0024 12 0 0 0 4.65E+07 3.23E+07 - - - 6.0483 0.9997 221125_WJC_METTL3_EV_vs_WT_F01.20560.20560.3 0.00926 17/56 K.LLGASELPIVTPALR.A "sp|P52292|IMA1_HUMAN,tr|A0A7I2V3Z3|A0A7I2V3Z3_HUMAN,tr|A0A7I2YQE1|A0A7I2YQE1_HUMAN,tr|A0A7I2V487|A0A7I2V487_HUMAN,tr|A0A7I2V351|A0A7I2V351_HUMAN" 5 1548.9239 1.31 7995 20560 3 1548.922881 517.3153 Importin subunit alpha-1 OS=Homo sapiens OX=9606 GN=KPNA2 PE=1 SV=1 6 3787 - 1.56E+06 - - - -0.6766 - 2.2 0.337 - 285.6 1 2 0 -0.001 15 0 0 0 3.62E+07 2.76E+07 - - - 4.3543 0.9992 221125_WJC_METTL3_EV_vs_WT_F01.20561.20561.2 0.00149 16-Oct K.IGFPWSEIR.N "sp|P15311|EZRI_HUMAN,sp|P26038|MOES_HUMAN,sp|P35241|RADI_HUMAN,tr|A0A2R8Y5S7|A0A2R8Y5S7_HUMAN,tr|E7EQR4|E7EQR4_HUMAN,tr|A0A2R8Y7M3|A0A2R8Y7M3_HUMAN" 6 1103.5764 0.55 7996 20561 2 1103.573717 552.7955 Ezrin OS=Homo sapiens OX=9606 GN=EZR PE=1 SV=4 6 3787.1 - 1.41E+06 - - - -2.4131 - 1.704 0.423 - 272 1 2 0 -0.0027 9 0 0 0 2.70E+07 4.86E+07 - - - 3.7064 0.9999 221125_WJC_METTL3_EV_vs_WT_F01.20562.20562.2 3.99E-05 15/24 K.ILGVWDTAVSLGK.L sp|Q53RT3|APRV1_HUMAN 1 1357.7606 27.77 7997 20562 2 1357.758944 679.8876 Retroviral-like aspartic protease 1 OS=Homo sapiens OX=9606 GN=ASPRV1 PE=1 SV=1 5.84 3787.2 - 947455 - - - -1.1843 - 2.518 0.5 - 704.6 1 2 0 -0.0016 13 0 0 0 2.61E+07 9.40E+05 - - - 5.1036 0.9993 221125_WJC_METTL3_EV_vs_WT_F01.20563.20563.2 0.021 22-Dec R.VPFLVLEC[160.03]PNLK.L "sp|Q9NRP0|OSTC_HUMAN,tr|A0A087WUD3|A0A087WUD3_HUMAN" 2 1427.7847 0.64 7998 20563 2 1427.780332 714.8996 Oligosaccharyltransferase complex subunit OSTC OS=Homo sapiens OX=9606 GN=OSTC PE=1 SV=1 5.97 3787.3 - 721482 - - - -3.0299 - 2.42 0.432 - 688.3 1 2 0 -0.0043 12 0 0 0 4.72E+06 7.35E+06 - - - 4.5557 1 221125_WJC_METTL3_EV_vs_WT_F01.20572.20572.3 1.40E-07 Dec-44 R.LFPPQWIC[160.03]C[160.03]DIR[166.11].Y sp|Q86U44|MTA70_HUMAN 1 1613.7722 -1 8006 20572 3 1613.770571 538.9313 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 5.82 3788.5 - 4.75E+07 - - - -1.0156 - 2.216 0.641 - 204.2 1 2 0 -0.0016 12 0 0 0 0.00E+00 0.00E+00 - - - 7.8916 1 221125_WJC_METTL3_EV_vs_WT_F01.20573.20573.2 3.58E-07 15/18 F.PPQWIC[160.03]C[160.03]DIR[166.11].Y sp|Q86U44|MTA70_HUMAN 1 1353.6197 0.001 8007 20573 2 1353.612577 677.8171 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 6.18 3788.5 - 4.67E+06 - - - -5.2858 - 2.804 0.539 - 816.5 1 1 0 -0.0072 10 0 0 0 0.00E+00 4.57E+07 - - - 5.8978 0.9998 221125_WJC_METTL3_EV_vs_WT_F01.20575.20575.2 8.66E-07 15/22 R.VPDGMVGLIIGR[166.11].G "sp|Q92945|FUBP2_HUMAN,tr|M0QYH3|M0QYH3_HUMAN,tr|M0R0C6|M0R0C6_HUMAN,tr|M0QXW7|M0QXW7_HUMAN,tr|A0A087WTP3|A0A087WTP3_HUMAN" 5 1235.6935 1.43 8009 20575 2 1235.691168 618.8541 Far upstream element-binding protein 2 OS=Homo sapiens OX=9606 GN=KHSRP PE=1 SV=4 5.81 3788.6 - 2.37E+06 - - - -1.926 - 2.603 0.543 - 938.1 1 2 0 -0.0024 12 0 0 0 4.63E+07 3.23E+07 - - - 5.568 0.9698 221125_WJC_METTL3_EV_vs_WT_F01.20576.20576.2 0.000103 20-Sep D.GMVPFVFVGTK[136.11].E "sp|P51114|FXR1_HUMAN,sp|Q06787|FMR1_HUMAN,tr|E7EU85|E7EU85_HUMAN,tr|E9PFF5|E9PFF5_HUMAN,tr|R9WNI0|R9WNI0_HUMAN,tr|A8MQB8|A8MQB8_HUMAN,tr|A0A087WXI3|A0A087WXI3_HUMAN,tr|B4DXZ6|B4DXZ6_HUMAN,tr|G3V0J0|G3V0J0_HUMAN" 9 1188.6457 1.88 8010 20576 2 1188.643383 595.3301 Fragile X mental retardation syndrome-related protein 1 OS=Homo sapiens OX=9606 GN=FXR1 PE=1 SV=3 8.75 3788.7 - 1.70E+06 - - - -1.9089 - 1.662 0.454 - 276.1 1 1 0 -0.0023 11 0 0 0 6.30E+07 3.36E+07 - - - 3.7679 0.7875 221125_WJC_METTL3_EV_vs_WT_F01.20580.20580.2 0.141 16-Jul T.GNLISSLPK[136.11].E sp|A4D1F6|LRRD1_HUMAN 1 935.5531 0.58 8014 20580 2 935.551418 468.7838 Leucine-rich repeat and death domain-containing protein 1 OS=Homo sapiens OX=9606 GN=LRRD1 PE=2 SV=2 8.75 3789.2 - 803196 - - - -1.8321 - 1.335 0.243 - 176.2 1 1 0 -0.0017 9 0 0 0 2.80E+06 4.82E+06 - - - 1.6712 0.9976 221125_WJC_METTL3_EV_vs_WT_F01.20588.20588.2 0.0773 14-Aug K.LLELLWNK.Y "sp|Q92905|CSN5_HUMAN,tr|E5RHH5|E5RHH5_HUMAN" 2 1027.6066 1.25 8022 20588 2 1027.6055 514.8106 COP9 signalosome complex subunit 5 OS=Homo sapiens OX=9606 GN=COPS5 PE=1 SV=4 6 3790.2 - 233024 - - - -1.087 - 1.762 0.147 - 164.5 1 2 0 -0.0011 8 0 0 0 5.81E+06 4.66E+06 - - - 1.8348 0.9996 221125_WJC_METTL3_EV_vs_WT_F01.20590.20590.2 5.33E-08 13/20 K.WYLENVYPELR[166.11].V sp|Q10471|GALT2_HUMAN 1 1490.7433 1.64 8023 20590 2 1490.739832 746.3789 Polypeptide N-acetylgalactosaminyltransferase 2 OS=Homo sapiens OX=9606 GN=GALNT2 PE=1 SV=1 4.53 3790.5 - 2.30E+06 - - - -2.3498 - 2.377 0.458 - 636.8 1 2 0 -0.0035 11 0 0 0 3.94E+07 2.40E+07 - - - 4.765 0.9998 221125_WJC_METTL3_EV_vs_WT_F01.20593.20593.2 0.000249 20-Oct K.LFTAESLIGLK[136.11].N "sp|P48444|COPD_HUMAN,tr|B0YIW6|B0YIW6_HUMAN" 2 1198.7053 0.53 8026 20593 2 1198.703962 600.3599 Coatomer subunit delta OS=Homo sapiens OX=9606 GN=ARCN1 PE=1 SV=1 6 3790.7 - 4.00E+06 - - - -1.0953 - 1.976 0.488 - 285.7 1 2 0 -0.0013 11 0 0 0 1.21E+07 2.27E+07 - - - 4.4874 0.9998 221125_WJC_METTL3_EV_vs_WT_F01.20596.20596.2 2.83E-08 24-Dec K.TPMIAGGLFVMDK.F sp|Q10471|GALT2_HUMAN 1 1378.6989 2.03 8029 20596 2 1378.696057 690.3567 Polypeptide N-acetylgalactosaminyltransferase 2 OS=Homo sapiens OX=9606 GN=GALNT2 PE=1 SV=1 5.5 3790.9 - 1.87E+06 - - - -2.0476 - 2.588 0.546 - 458.6 1 2 0 -0.0028 13 0 0 0 1.51E+07 7.43E+06 - - - 5.5133 0.9911 221125_WJC_METTL3_EV_vs_WT_F01.20600.20600.3 0.134 Oct-44 K.GIDPFSLDALSK[136.11].E sp|P40227|TCPZ_HUMAN 1 1269.6696 0.54 8033 20600 3 1269.668336 424.2305 T-complex protein 1 subunit zeta OS=Homo sapiens OX=9606 GN=CCT6A PE=1 SV=3 4.21 3791.5 - 588158 - - - -1.0097 - 1.504 0.198 - 84 1 2 0 -0.0013 12 0 0 0 1.60E+06 2.97E+06 - - - 1.8784 0.9703 221125_WJC_METTL3_EV_vs_WT_F01.20601.20601.2 1.54 12-May K.LNIWDWK.T sp|O60508|PRP17_HUMAN 1 973.5022 1.76 8034 20601 2 973.500261 487.7584 Pre-mRNA-processing factor 17 OS=Homo sapiens OX=9606 GN=CDC40 PE=1 SV=1 5.84 3791.6 - 379264 - - - -1.9425 - 1.199 0.102 - 85.2 1 2 0 -0.0019 7 0 0 0 5.31E+06 3.01E+06 - - - 0.3688 1 221125_WJC_METTL3_EV_vs_WT_F01.20608.20608.2 6.23E-07 17/24 K.TPMIAGGLFVMDK[136.11].F sp|Q10471|GALT2_HUMAN 1 1386.7131 2.03 8039 20608 2 1386.705994 694.3638 Polypeptide N-acetylgalactosaminyltransferase 2 OS=Homo sapiens OX=9606 GN=GALNT2 PE=1 SV=1 5.5 3792.5 - 1.13E+06 - - - -5.1099 - 3.207 0.515 - 1229.2 1 2 0 -0.0071 13 0 0 0 1.51E+07 7.43E+06 - - - 5.8334 0.9852 221125_WJC_METTL3_EV_vs_WT_F01.20609.20609.2 0.0266 16-Aug K.IELPELFDR.G "sp|Q9Y2Z4|SYYM_HUMAN,tr|H0YHS6|H0YHS6_HUMAN" 2 1130.5972 2.39 8040 20609 2 1130.602544 566.3059 "Tyrosine--tRNA ligase, mitochondrial OS=Homo sapiens OX=9606 GN=YARS2 PE=1 SV=2" 4.14 3792.6 - 590089 - - - 4.7488 - 1.65 0.267 - 197.1 1 2 0 0.0054 9 0 0 0 2.24E+07 9.34E+06 - - - 2.4601 0.9997 221125_WJC_METTL3_EV_vs_WT_F01.20610.20610.2 1.46E-06 15/24 K.LSLAEIYEQEYIK.L sp|O00566|MPP10_HUMAN 1 1597.8239 2.98 8041 20610 2 1597.819567 799.9192 U3 small nucleolar ribonucleoprotein protein MPP10 OS=Homo sapiens OX=9606 GN=MPHOSPH10 PE=1 SV=2 4.25 3792.7 - 517777 - - - -2.7368 - 2.714 0.52 - 918.2 1 2 0 -0.0044 13 0 0 0 7.57E+06 2.54E+06 - - - 5.4428 0.9714 221125_WJC_METTL3_EV_vs_WT_F01.20613.20613.2 2.54E-06 20-Sep D.GMVPFVFVGTK.E "sp|P51114|FXR1_HUMAN,sp|Q06787|FMR1_HUMAN,tr|E7EU85|E7EU85_HUMAN,tr|E9PFF5|E9PFF5_HUMAN,tr|R9WNI0|R9WNI0_HUMAN,tr|A8MQB8|A8MQB8_HUMAN,tr|A0A087WXI3|A0A087WXI3_HUMAN,tr|B4DXZ6|B4DXZ6_HUMAN,tr|G3V0J0|G3V0J0_HUMAN" 9 1180.6315 1.56 8042 20613 2 1180.62832 591.323 Fragile X mental retardation syndrome-related protein 1 OS=Homo sapiens OX=9606 GN=FXR1 PE=1 SV=3 8.75 3793.1 - 2.96E+06 - - - -2.6528 - 1.845 0.527 - 333.4 1 1 0 -0.0031 11 0 0 0 3.76E+07 2.41E+07 - - - 4.5893 0.9446 221125_WJC_METTL3_EV_vs_WT_F01.20615.20615.2 0.0539 20-Jul K.INEAFIEMATT.E "sp|P43243|MATR3_HUMAN,tr|D6RE02|D6RE02_HUMAN,tr|B3KM87|B3KM87_HUMAN,tr|A8MXP9|A8MXP9_HUMAN,tr|D6RBK5|D6RBK5_HUMAN,tr|A0A0R4J2E8|A0A0R4J2E8_HUMAN,tr|H0Y8T4|H0Y8T4_HUMAN,tr|D6REM6|D6REM6_HUMAN,tr|D6RBI2|D6RBI2_HUMAN" 9 1238.5853 - 8044 20615 2 1238.586246 620.2999 Matrin-3 OS=Homo sapiens OX=9606 GN=MATR3 PE=1 SV=2 3.79 3793.3 - 1.79E+06 - - - 0.7718 - 1.421 0.347 - 129.1 1 1 0 0.001 11 0 0 0 - - - - - 2.5542 0.9998 221125_WJC_METTL3_EV_vs_WT_F01.20620.20620.2 0.00333 14-Sep K.EALLELLR.L sp|Q13895|BYST_HUMAN 1 955.5702 0.86 8049 20620 2 955.569227 478.7924 Bystin OS=Homo sapiens OX=9606 GN=BYSL PE=1 SV=3 4.53 3793.9 - 686438 - - - -1.0517 - 2.014 0.396 - 315.5 1 2 0 -0.001 8 0 0 0 2.60E+07 3.04E+07 - - - 4.0771 1 221125_WJC_METTL3_EV_vs_WT_F01.20626.20626.2 1.04E-08 16/30 R.LMNETTAVALAYGIYK[136.11].Q "sp|O95757|HS74L_HUMAN,sp|P34932|HSP74_HUMAN,tr|A0A087WTS8|A0A087WTS8_HUMAN,tr|D6RJ96|D6RJ96_HUMAN,tr|E9PDE8|E9PDE8_HUMAN,tr|A0A087WYC1|A0A087WYC1_HUMAN" 6 1764.9212 0.05 8053 20626 2 1764.919724 883.4679 Heat shock 70 kDa protein 4L OS=Homo sapiens OX=9606 GN=HSPA4L PE=1 SV=3 6 3794.7 - 1.88E+06 - - - -0.8125 - 3.504 0.606 - 993.4 1 2 0 -0.0014 16 0 0 0 1.36E+06 2.66E+07 - - - 6.5992 0.9789 221125_WJC_METTL3_EV_vs_WT_F01.20627.20627.2 0.000346 18-Oct L.DPFSLDALSK[136.11].E sp|P40227|TCPZ_HUMAN 1 1099.5641 0.05 8054 20627 2 1099.56564 550.7893 T-complex protein 1 subunit zeta OS=Homo sapiens OX=9606 GN=CCT6A PE=1 SV=3 4.21 3794.7 - 1.49E+06 - - - 1.4096 - 1.939 0.415 - 310.5 1 1 0 0.0015 10 0 0 0 1.70E+06 3.28E+07 - - - 3.954 0.9911 221125_WJC_METTL3_EV_vs_WT_F01.20629.20629.2 0.0114 20-Dec M.LAVDAVIAELK[136.11].K "sp|P10809|CH60_HUMAN,tr|A0A7I2V2X6|A0A7I2V2X6_HUMAN,tr|A0A7I2V599|A0A7I2V599_HUMAN,tr|E7EXB4|E7EXB4_HUMAN,tr|A0A7I2YQ71|A0A7I2YQ71_HUMAN,tr|E7ESH4|E7ESH4_HUMAN,tr|A0A7I2V5M1|A0A7I2V5M1_HUMAN,tr|A0A7I2V5K3|A0A7I2V5K3_HUMAN,tr|A0A7I2V369|A0A7I2V369_HUMAN" 9 1148.6896 1.6 8056 20629 2 1148.690118 575.3521 "60 kDa heat shock protein, mitochondrial OS=Homo sapiens OX=9606 GN=HSPD1 PE=1 SV=2" 4.37 3795 - 869044 - - - 0.4292 - 2.664 0.395 - 319.7 1 1 0 0.0005 11 0 0 0 9.76E+06 6.10E+06 - - - 4.609 0.9897 221125_WJC_METTL3_EV_vs_WT_F01.20631.20631.2 0.00245 22-Aug K.LDEFYIGQIPLK[136.11].E "sp|O15047|SET1A_HUMAN,tr|A0A804HLA6|A0A804HLA6_HUMAN" 2 1442.7901 1.44 8058 20631 2 1442.783638 722.4023 Histone-lysine N-methyltransferase SETD1A OS=Homo sapiens OX=9606 GN=SETD1A PE=1 SV=3 4.37 3795.3 - 484653 - - - -4.4566 - 1.586 0.314 - 224.1 1 2 0 -0.0064 12 0 0 0 2.24E+06 1.55E+06 - - - 2.5717 0.9997 221125_WJC_METTL3_EV_vs_WT_F01.20637.20637.3 4.50E-07 14/60 R.LMNETTAVALAYGIYK[136.11].Q "sp|O95757|HS74L_HUMAN,sp|P34932|HSP74_HUMAN,tr|A0A087WTS8|A0A087WTS8_HUMAN,tr|D6RJ96|D6RJ96_HUMAN,tr|E9PDE8|E9PDE8_HUMAN,tr|A0A087WYC1|A0A087WYC1_HUMAN" 6 1764.9212 0.08 8062 20637 3 1764.919246 589.3143 Heat shock 70 kDa protein 4L OS=Homo sapiens OX=9606 GN=HSPA4L PE=1 SV=3 6 3796.1 - 2.90E+06 - - - -1.0833 - 2.324 0.311 - 320.1 1 2 0 -0.0019 16 0 0 0 1.64E+06 2.09E+07 - - - 4.1706 0.9997 221125_WJC_METTL3_EV_vs_WT_F01.20639.20639.2 3.68E-05 22-Jul R.LFPPQWIC[160.03]C[160.03]DIR[166.11].Y sp|Q86U44|MTA70_HUMAN 1 1613.7722 0.02 8064 20639 2 1613.769693 807.8934 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 5.82 3796.2 - 2.05E+08 - - - -1.5597 - 1.676 0.532 - 119.5 1 2 0 -0.0025 12 0 0 0 1.18E+08 5.51E+09 - - - 4.3283 0.9994 221125_WJC_METTL3_EV_vs_WT_F01.20640.20640.2 0.00119 14-Jul K.DLEDLFYK.Y "sp|Q13242|SRSF9_HUMAN,tr|H0YIB4|H0YIB4_HUMAN,tr|S4R3G0|S4R3G0_HUMAN" 3 1041.5019 1.68 8065 20640 2 1041.5007 521.7582 Serine\arginine-rich splicing factor 9 OS=Homo sapiens OX=9606 GN=SRSF9 PE=1 SV=1 4.03 3796.3 - 1.57E+06 - - - -1.1311 - 1.57 0.371 - 148.6 1 2 0 -0.0012 8 0 0 0 1.64E+07 9.77E+06 - - - 3.1413 0.9998 221125_WJC_METTL3_EV_vs_WT_F01.20641.20641.2 6.36E-06 22-Sep K.LFMAQALQEYNN.- "sp|O15372|EIF3H_HUMAN,tr|B3KS98|B3KS98_HUMAN,tr|A0A087WZK9|A0A087WZK9_HUMAN" 3 1440.6708 - 8066 20641 2 1440.669579 721.3427 Eukaryotic translation initiation factor 3 subunit H OS=Homo sapiens OX=9606 GN=EIF3H PE=1 SV=1 4 3796.4 - 1.26E+06 - - - -0.8135 - 1.943 0.471 - 214 1 2 0 -0.0012 12 0 0 0 - - - - - 4.2671 0.9937 221125_WJC_METTL3_EV_vs_WT_F01.20642.20642.2 3.55E-05 22-Nov R.PASPSLQLLPWR.E sp|Q8WUF5|IASPP_HUMAN 1 1363.7612 2.67 8067 20642 2 1363.76148 682.8879 RelA-associated inhibitor OS=Homo sapiens OX=9606 GN=PPP1R13L PE=1 SV=4 10.18 3796.5 - 872449 - - - 0.1899 - 2.619 0.486 - 450.7 1 1 0 0.0003 12 0 0 0 9.49E+06 3.56E+06 - - - 5.1638 0.9997 221125_WJC_METTL3_EV_vs_WT_F01.20643.20643.2 0.0035 14-Aug K.DLEDLFYK[136.11].Y "sp|Q13242|SRSF9_HUMAN,tr|H0YIB4|H0YIB4_HUMAN,tr|S4R3G0|S4R3G0_HUMAN" 3 1049.5161 1.67 8068 20643 2 1049.515641 525.7653 Serine\arginine-rich splicing factor 9 OS=Homo sapiens OX=9606 GN=SRSF9 PE=1 SV=1 4.03 3796.6 - 846753 - - - -0.4164 - 1.653 0.43 - 179.1 1 2 0 -0.0004 8 0 0 0 1.63E+07 9.77E+06 - - - 3.7326 0.9994 221125_WJC_METTL3_EV_vs_WT_F01.20647.20647.2 0.00653 14-Sep R.QVLPFLLR[166.11].R "sp|O14981|BTAF1_HUMAN,tr|A0A0A0MTH9|A0A0A0MTH9_HUMAN" 2 994.6203 0.8 8072 20647 2 994.620782 498.3174 TATA-binding protein-associated factor 172 OS=Homo sapiens OX=9606 GN=BTAF1 PE=1 SV=2 9.75 3797.2 - 346814 - - - 0.4776 - 1.753 0.287 - 277.3 1 2 0 0.0005 8 0 0 0 1.80E+06 2.23E+06 - - - 2.8536 0.8249 221125_WJC_METTL3_EV_vs_WT_F01.20648.20648.2 0.0239 12-Sep L.PLQDVYK[136.11].L "sp|Q05639|EF1A2_HUMAN,sp|P68104|EF1A1_HUMAN,sp|Q5VTE0|EF1A3_HUMAN,tr|A0A7I2V659|A0A7I2V659_HUMAN,tr|A0A7I2V3H3|A0A7I2V3H3_HUMAN,tr|A0A2U3TZH3|A0A2U3TZH3_HUMAN,tr|A0A7I2V5N4|A0A7I2V5N4_HUMAN,tr|A0A087WVQ9|A0A087WVQ9_HUMAN,tr|A0A087WV01|A0A087WV01_HUMAN" 9 869.4738 0.62 8073 20648 2 869.47198 435.7442 Elongation factor 1-alpha 2 OS=Homo sapiens OX=9606 GN=EEF1A2 PE=1 SV=1 6.26 3797.3 - 265251 - - - -2.1151 - 1.802 0.151 - 271.4 1 1 0 -0.0018 7 0 0 0 1.44E+06 2.34E+06 - - - 2.0217 0.9992 221125_WJC_METTL3_EV_vs_WT_F01.20652.20652.2 0.00391 20-Oct K.ELGIWEPLAVK[136.11].L "sp|P49368|TCPG_HUMAN,tr|B4DUR8|B4DUR8_HUMAN" 2 1261.7162 0.24 8075 20652 2 1261.714745 631.8654 T-complex protein 1 subunit gamma OS=Homo sapiens OX=9606 GN=CCT3 PE=1 SV=4 4.53 3797.7 - 5.59E+06 - - - -1.1326 - 1.891 0.276 - 362.2 1 2 0 -0.0014 11 0 0 0 1.12E+08 4.70E+08 - - - 2.8026 0.9999 221125_WJC_METTL3_EV_vs_WT_F01.20654.20654.2 1.57E-05 22-Oct R.LFPPQWIC[160.03]C[160.03]DIR.Y sp|Q86U44|MTA70_HUMAN 1 1603.7639 0.02 8077 20654 2 1603.763135 802.8892 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 5.82 3797.8 - 4.56E+06 - - - -0.5019 - 2.076 0.532 - 288.4 1 2 0 -0.0008 12 0 0 0 1.18E+08 5.51E+09 - - - 4.892 0.9999 221125_WJC_METTL3_EV_vs_WT_F01.20656.20656.2 0.00258 14/22 K.DLLNMYIETEGK[136.11].M "sp|Q92598|HS105_HUMAN,tr|A0A0A0MSM0|A0A0A0MSM0_HUMAN" 2 1432.6999 0.14 8079 20656 2 1432.698502 717.3572 Heat shock protein 105 kDa OS=Homo sapiens OX=9606 GN=HSPH1 PE=1 SV=1 4.14 3798 - 1.25E+06 - - - -0.9981 - 2.743 0.532 - 657.7 1 2 0 -0.0014 12 0 0 0 1.59E+06 1.15E+07 - - - 5.6249 0.9999 221125_WJC_METTL3_EV_vs_WT_F01.20657.20657.2 4.96E-06 14/26 K.ILPTLEAVAALGNK.V "sp|Q12905|ILF2_HUMAN,tr|B4DY09|B4DY09_HUMAN,tr|X6R6Z1|X6R6Z1_HUMAN" 3 1408.829 1.27 8080 20657 2 1408.827622 705.4218 Interleukin enhancer-binding factor 2 OS=Homo sapiens OX=9606 GN=ILF2 PE=1 SV=2 6 3798.2 - 1.16E+06 - - - -0.954 - 2.82 0.509 - 794.3 1 2 0 -0.0013 14 0 0 0 1.28E+08 1.01E+08 - - - 5.4017 0.9921 221125_WJC_METTL3_EV_vs_WT_F01.20661.20661.2 0.000335 22-Oct R.PASPSLQLLPWR[166.11].E sp|Q8WUF5|IASPP_HUMAN 1 1373.7695 2.67 8084 20661 2 1373.770403 687.892 RelA-associated inhibitor OS=Homo sapiens OX=9606 GN=PPP1R13L PE=1 SV=4 10.18 3798.7 - 575455 - - - 0.6639 - 2.395 0.489 - 450.9 1 1 0 0.0009 12 0 0 0 9.49E+06 3.56E+06 - - - 4.9505 0.9998 221125_WJC_METTL3_EV_vs_WT_F01.20662.20662.2 1.54E-07 22-Dec R.IFGDNFDPDFIK.Q "sp|Q96BR1|SGK3_HUMAN,tr|E5RJV7|E5RJV7_HUMAN,tr|E5RK28|E5RK28_HUMAN,tr|E5RHY6|E5RHY6_HUMAN,tr|E5RHX2|E5RHX2_HUMAN" 5 1426.6769 0.71 8085 20662 2 1426.673985 714.3457 Serine\threonine-protein kinase Sgk3 OS=Homo sapiens OX=9606 GN=SGK3 PE=1 SV=1 3.93 3798.8 - 554150 - - - -2.0306 - 2.224 0.564 - 378 1 2 0 -0.0029 12 0 0 0 3.90E+06 5.51E+06 - - - 5.3089 0.991 221125_WJC_METTL3_EV_vs_WT_F01.20665.20665.2 0.000124 18-Sep R.QALTDFLLAR[166.11].K "sp|Q8WTW3|COG1_HUMAN,tr|E9PBL8|E9PBL8_HUMAN,tr|A0A087WVI0|A0A087WVI0_HUMAN" 3 1156.648 1.94 8088 20665 2 1156.642359 579.3313 Conserved oligomeric Golgi complex subunit 1 OS=Homo sapiens OX=9606 GN=COG1 PE=1 SV=1 5.84 3799.2 - 233838 - - - -4.858 - 2.087 0.256 - 205.1 1 2 0 -0.0056 10 0 0 0 1.50E+07 7.72E+06 - - - 2.9837 1 221125_WJC_METTL3_EV_vs_WT_F01.20669.20669.2 8.36E-06 13/26 K.ILPTLEAVAALGNK[136.11].V "sp|Q12905|ILF2_HUMAN,tr|B4DY09|B4DY09_HUMAN,tr|X6R6Z1|X6R6Z1_HUMAN" 3 1416.8432 1.27 8090 20669 2 1416.840902 709.4289 Interleukin enhancer-binding factor 2 OS=Homo sapiens OX=9606 GN=ILF2 PE=1 SV=2 6 3799.7 - 2.01E+06 - - - -1.5979 - 2.7 0.568 - 594.6 1 2 0 -0.0023 14 0 0 0 1.28E+08 1.01E+08 - - - 5.7281 1 221125_WJC_METTL3_EV_vs_WT_F01.20671.20671.2 9.91E-07 14/24 K.VLGTAFDPFLGGK[136.11].N "sp|Q92598|HS105_HUMAN,tr|A0A0A0MSM0|A0A0A0MSM0_HUMAN" 2 1328.722 0.14 8092 20671 2 1328.72024 665.3683 Heat shock protein 105 kDa OS=Homo sapiens OX=9606 GN=HSPH1 PE=1 SV=1 5.81 3799.8 - 1.84E+06 - - - -1.3155 - 2.722 0.573 - 481 1 2 0 -0.0017 13 0 0 0 2.72E+07 1.98E+08 - - - 5.8427 0.9996 221125_WJC_METTL3_EV_vs_WT_F01.20672.20672.2 7.94E-06 18-Oct K.GYGFVSFFNK[136.11].W "sp|P31483|TIA1_HUMAN,tr|F8W8I6|F8W8I6_HUMAN,tr|C9JTN7|C9JTN7_HUMAN,tr|H7BY49|H7BY49_HUMAN" 4 1172.5746 1.81 8093 20672 2 1172.572001 587.2946 Nucleolysin TIA-1 isoform p40 OS=Homo sapiens OX=9606 GN=TIA1 PE=1 SV=3 8.59 3799.9 - 1.23E+06 - - - -2.2122 - 2.052 0.481 - 319.7 1 2 0 -0.0026 10 0 0 0 2.33E+07 1.28E+07 - - - 4.5993 0.9994 221125_WJC_METTL3_EV_vs_WT_F01.20673.20673.2 0.000561 18-Jul K.GYGFVSFFNK.W "sp|P31483|TIA1_HUMAN,tr|F8W8I6|F8W8I6_HUMAN,tr|C9JTN7|C9JTN7_HUMAN,tr|H7BY49|H7BY49_HUMAN" 4 1164.5604 1.81 8094 20673 2 1164.558704 583.2875 Nucleolysin TIA-1 isoform p40 OS=Homo sapiens OX=9606 GN=TIA1 PE=1 SV=3 8.59 3800 - 1.22E+06 - - - -1.4521 - 1.432 0.443 - 132.5 1 2 0 -0.0017 10 0 0 0 2.33E+07 1.28E+07 - - - 3.3147 1 221125_WJC_METTL3_EV_vs_WT_F01.20674.20674.3 7.40E-06 15/52 K.ILPTLEAVAALGNK.V "sp|Q12905|ILF2_HUMAN,tr|B4DY09|B4DY09_HUMAN,tr|X6R6Z1|X6R6Z1_HUMAN" 3 1408.829 1.31 8095 20674 3 1408.827222 470.6169 Interleukin enhancer-binding factor 2 OS=Homo sapiens OX=9606 GN=ILF2 PE=1 SV=2 6 3800.1 - 835117 - - - -1.2379 - 2.933 0.417 - 319.9 1 2 0 -0.0017 14 0 0 0 3.45E+07 2.64E+07 - - - 6.0482 1 221125_WJC_METTL3_EV_vs_WT_F01.20677.20677.3 1.23E-07 18/52 K.ILPTLEAVAALGNK[136.11].V "sp|Q12905|ILF2_HUMAN,tr|B4DY09|B4DY09_HUMAN,tr|X6R6Z1|X6R6Z1_HUMAN" 3 1416.8432 1.31 8098 20677 3 1416.840611 473.2883 Interleukin enhancer-binding factor 2 OS=Homo sapiens OX=9606 GN=ILF2 PE=1 SV=2 6 3800.5 - 576108 - - - -1.8033 - 3.321 0.486 - 477.9 1 2 0 -0.0026 14 0 0 0 3.45E+07 2.62E+07 - - - 7.1475 0.999 221125_WJC_METTL3_EV_vs_WT_F01.20680.20680.2 0.00351 18-Sep K.EFLFNPYLTR[166.11].K "sp|P13378|HXD8_HUMAN,sp|P31273|HXC8_HUMAN,sp|P17481|HXB8_HUMAN,tr|I3L3R1|I3L3R1_HUMAN,tr|I3L383|I3L383_HUMAN,tr|A0A0A0MSX5|A0A0A0MSX5_HUMAN,tr|A0A0A0MTF4|A0A0A0MTF4_HUMAN" 7 1308.6742 1.18 8101 20680 2 1308.671025 655.3444 Homeobox protein Hox-D8 OS=Homo sapiens OX=9606 GN=HOXD8 PE=1 SV=2 6.1 3800.9 - 494266 - - - -2.4208 - 1.74 0.38 - 388.8 1 2 0 -0.0032 10 0 0 0 4.54E+06 3.86E+06 - - - 3.3927 0.906 221125_WJC_METTL3_EV_vs_WT_F01.20691.20691.2 0.00271 16-Jul R.FYTLIPHDF.G "sp|P09874|PARP1_HUMAN,tr|A0A7I2V3E1|A0A7I2V3E1_HUMAN" 2 1151.5651 - 8110 20691 2 1151.565019 576.7898 Poly [ADP-ribose] polymerase 1 OS=Homo sapiens OX=9606 GN=PARP1 PE=1 SV=4 5.08 3802.3 - 2.53E+06 - - - -0.1112 - 1.132 0.339 - 117.4 1 1 0 -0.0001 9 0 0 0 - - - - - 1.9035 0.9997 221125_WJC_METTL3_EV_vs_WT_F01.20694.20694.2 0.00035 20-Oct K.TLPLFYGSIVR[166.11].F "sp|A6NHR9|SMHD1_HUMAN,tr|J3KTL8|J3KTL8_HUMAN" 2 1274.7262 8.27 8113 20694 2 1274.725463 638.3704 Structural maintenance of chromosomes flexible hinge domain-containing protein 1 OS=Homo sapiens OX=9606 GN=SMCHD1 PE=1 SV=2 8.41 3802.5 - 1.01E+06 - - - -0.6009 - 1.805 0.385 - 343 1 2 0 -0.0008 11 0 0 0 5.45E+07 6.60E+06 - - - 3.482 0.9998 221125_WJC_METTL3_EV_vs_WT_F01.20704.20704.2 0.00237 16-Oct R.YLDVSILGK[136.11].F sp|Q86U44|MTA70_HUMAN 1 1014.5841 0.11 8122 20704 2 1014.583423 508.2993 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 5.83 3803.8 - 4.14E+06 - - - -0.6653 - 1.924 0.481 - 237.7 1 2 0 -0.0007 9 0 0 0 2.75E+06 2.45E+07 - - - 4.4867 0.997 221125_WJC_METTL3_EV_vs_WT_F01.20705.20705.2 0.536 14-Jul R.VDEIIWVK[136.11].T sp|Q86U44|MTA70_HUMAN 1 1008.5735 0.05 8123 20705 2 1008.572894 505.294 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 4.37 3803.9 - 519194 - - - -0.6336 - 1.54 0.16 - 132.4 1 2 0 -0.0006 8 0 0 0 6.43E+05 1.23E+07 - - - 1.5248 0.9995 221125_WJC_METTL3_EV_vs_WT_F01.20707.20707.2 0.0113 18-Aug K.DLFDPIIEDR[166.11].H "sp|P12277|KCRB_HUMAN,tr|G3V461|G3V461_HUMAN,tr|G3V4N7|G3V4N7_HUMAN" 3 1241.6167 1.06 8125 20707 2 1241.615802 621.8156 Creatine kinase B-type OS=Homo sapiens OX=9606 GN=CKB PE=1 SV=1 3.84 3804 - 1.71E+06 - - - -0.7539 - 1.733 0.354 - 198.6 1 2 0 -0.0009 10 0 0 0 1.14E+07 1.08E+07 - - - 3.1902 0.9148 221125_WJC_METTL3_EV_vs_WT_F01.20708.20708.2 0.0534 14-Aug F.LFLWVTGR[166.11].A sp|Q86U44|MTA70_HUMAN 1 1000.5734 0.01 8126 20708 2 1000.571873 501.294 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 9.75 3804.1 - 1.62E+06 - - - -1.4831 - 1.494 0.286 - 333.1 1 1 0 -0.0015 8 0 0 0 3.29E+05 3.30E+07 - - - 2.3637 0.9927 221125_WJC_METTL3_EV_vs_WT_F01.20714.20714.2 9.49E-06 24-Oct Y.VVFIAAPELETLR.A "sp|Q9NZW5|PALS2_HUMAN,tr|B8ZZG1|B8ZZG1_HUMAN" 2 1456.829 5.46 8132 20714 2 1456.827963 729.4218 Protein PALS2 OS=Homo sapiens OX=9606 GN=PALS2 PE=1 SV=2 4.53 3804.9 - 309180 - - - -0.6885 - 2.131 0.54 - 360.6 1 1 0 -0.001 13 0 0 0 1.68E+06 3.08E+05 - - - 4.9709 0.9378 221125_WJC_METTL3_EV_vs_WT_F01.20715.20715.2 0.000177 24-Nov K.MVFINNIALAQIK[136.11].N "sp|P42704|LPPRC_HUMAN,tr|A0A804HI14|A0A804HI14_HUMAN,tr|A0A804HL40|A0A804HL40_HUMAN,tr|A0A804HKJ0|A0A804HKJ0_HUMAN,tr|A0A804HKR3|A0A804HKR3_HUMAN,tr|A0A804HIN4|A0A804HIN4_HUMAN,tr|A0A804HLG8|A0A804HLG8_HUMAN,tr|A0A804HJA1|A0A804HJA1_HUMAN,tr|A0A804HHY9|A0A804HHY9_HUMAN,tr|A0A804HI40|A0A804HI40_HUMAN,tr|A0A804HJZ1|A0A804HJZ1_HUMAN,tr|A0A804HIQ7|A0A804HIQ7_HUMAN,tr|A0A804HK30|A0A804HK30_HUMAN,tr|A0A804HKI2|A0A804HKI2_HUMAN,tr|A0A804HJI0|A0A804HJI0_HUMAN,tr|A0A804HKX6|A0A804HKX6_HUMAN,tr|A0A804HKK7|A0A804HKK7_HUMAN,tr|A0A804HIG4|A0A804HIG4_HUMAN" 18 1481.852 0.66 8133 20715 2 1482.850428 741.9333 "Leucine-rich PPR motif-containing protein, mitochondrial OS=Homo sapiens OX=9606 GN=LRPPRC PE=1 SV=3" 8.5 3805 - 219303 - - - 673.8001 - 1.996 0.421 - 308.2 1 2 0 0.9985 13 0 0 0 3.69E+06 5.58E+06 - - - 3.6108 0.9524 221125_WJC_METTL3_EV_vs_WT_F01.20717.20717.3 0.58 Sep-40 K.ELGIWEPLAVK[136.11].L "sp|P49368|TCPG_HUMAN,tr|B4DUR8|B4DUR8_HUMAN" 2 1261.7162 0.17 8135 20717 3 1261.714186 421.5793 T-complex protein 1 subunit gamma OS=Homo sapiens OX=9606 GN=CCT3 PE=1 SV=4 4.53 3805.3 - 187278 - - - -1.5756 - 1.417 0.137 - 115.5 1 2 0 -0.002 11 0 0 0 2.19E+05 1.27E+06 - - - 1.057 0.9997 221125_WJC_METTL3_EV_vs_WT_F01.20720.20720.2 3.64E-06 13/20 R.QLLEEMLTSYR[166.11].L sp|O75688|PPM1B_HUMAN 1 1391.6994 3.08 8136 20720 2 1391.696491 696.857 Protein phosphatase 1B OS=Homo sapiens OX=9606 GN=PPM1B PE=1 SV=1 4.53 3805.7 - 5.30E+06 - - - -2.1061 - 2.543 0.414 - 972.5 1 2 0 -0.0029 11 0 0 0 1.12E+08 3.63E+07 - - - 4.6228 0.9858 221125_WJC_METTL3_EV_vs_WT_F01.20722.20722.2 0.0012 18-Sep K.DLFDPIIEDR.H "sp|P12277|KCRB_HUMAN,tr|G3V461|G3V461_HUMAN,tr|G3V4N7|G3V4N7_HUMAN" 3 1231.6085 1.06 8138 20722 2 1231.600744 616.8115 Creatine kinase B-type OS=Homo sapiens OX=9606 GN=CKB PE=1 SV=1 3.84 3805.8 - 2.31E+06 - - - -6.2715 - 1.606 0.431 - 274.3 1 2 0 -0.0077 10 0 0 0 1.14E+07 1.08E+07 - - - 3.5443 0.9998 221125_WJC_METTL3_EV_vs_WT_F01.20723.20723.2 0.000569 20-Sep K.LLPAITILGC[160.03]R.V "sp|Q96IJ6|GMPPA_HUMAN,tr|A0A804HIS0|A0A804HIS0_HUMAN" 2 1225.7217 0.63 8139 20723 2 1225.721352 613.8681 Mannose-1-phosphate guanyltransferase alpha OS=Homo sapiens OX=9606 GN=GMPPA PE=1 SV=1 8.25 3805.9 - 1.43E+06 - - - -0.2545 - 1.877 0.436 - 264.2 1 2 0 -0.0003 11 0 0 0 4.90E+06 7.79E+06 - - - 3.9646 0.9987 221125_WJC_METTL3_EV_vs_WT_F01.20727.20727.3 0.00614 Nov-40 R.QLLEEMLTSYR.L sp|O75688|PPM1B_HUMAN 1 1381.6912 2.85 8143 20727 3 1381.690552 461.571 Protein phosphatase 1B OS=Homo sapiens OX=9606 GN=PPM1B PE=1 SV=1 4.53 3806.4 - 783764 - - - -0.4343 - 1.914 0.245 - 177.3 1 2 0 -0.0006 11 0 0 0 6.68E+06 2.34E+06 - - - 3.1156 1 221125_WJC_METTL3_EV_vs_WT_F01.20729.20729.2 8.81E-09 24-Dec K.MVFINNIALAQIK.N "sp|P42704|LPPRC_HUMAN,tr|A0A804HI14|A0A804HI14_HUMAN,tr|A0A804HL40|A0A804HL40_HUMAN,tr|A0A804HKJ0|A0A804HKJ0_HUMAN,tr|A0A804HKR3|A0A804HKR3_HUMAN,tr|A0A804HIN4|A0A804HIN4_HUMAN,tr|A0A804HLG8|A0A804HLG8_HUMAN,tr|A0A804HJA1|A0A804HJA1_HUMAN,tr|A0A804HHY9|A0A804HHY9_HUMAN,tr|A0A804HI40|A0A804HI40_HUMAN,tr|A0A804HJZ1|A0A804HJZ1_HUMAN,tr|A0A804HIQ7|A0A804HIQ7_HUMAN,tr|A0A804HK30|A0A804HK30_HUMAN,tr|A0A804HKI2|A0A804HKI2_HUMAN,tr|A0A804HJI0|A0A804HJI0_HUMAN,tr|A0A804HKX6|A0A804HKX6_HUMAN,tr|A0A804HKK7|A0A804HKK7_HUMAN,tr|A0A804HIG4|A0A804HIG4_HUMAN" 18 1473.8378 0.66 8145 20729 2 1473.840188 737.9262 "Leucine-rich PPR motif-containing protein, mitochondrial OS=Homo sapiens OX=9606 GN=LRPPRC PE=1 SV=3" 8.5 3806.7 - 558341 - - - 1.6501 - 2.645 0.579 - 466.6 1 2 0 0.0024 13 0 0 0 3.69E+06 5.58E+06 - - - 5.8131 0.9997 221125_WJC_METTL3_EV_vs_WT_F01.20733.20733.2 1.79E-05 13/34 K.ILDSFAAAPVPTTTLVLK.S sp|P18583|SON_HUMAN 1 1856.0659 1.9 8149 20733 2 1856.070132 929.0402 Protein SON OS=Homo sapiens OX=9606 GN=SON PE=1 SV=4 5.84 3807.2 - 431474 - - - 2.279 - 2.435 0.5 - 295.5 1 2 0 0.0042 18 0 0 0 1.07E+07 5.64E+06 - - - 4.9206 0.9906 221125_WJC_METTL3_EV_vs_WT_F01.20734.20734.2 0.282 30-Jul K.LPPPLSAPVAGLAALK[136.11].A sp|Q14781|CBX2_HUMAN 1 1521.9374 1.47 8150 20734 2 1521.933698 761.976 Chromobox protein homolog 2 OS=Homo sapiens OX=9606 GN=CBX2 PE=1 SV=2 8.75 3807.3 - 358759 - - - -2.4331 - 1.222 0.256 - 101.3 1 2 0 -0.0037 16 0 0 0 3.62E+06 2.46E+06 - - - 1.4236 0.9998 221125_WJC_METTL3_EV_vs_WT_F01.20736.20736.2 3.50E-06 22-Nov R.LALFNPDVC[160.03]WDR.N sp|O00483|NDUA4_HUMAN 1 1504.7133 0.67 8152 20736 2 1504.713326 753.3639 Cytochrome c oxidase subunit NDUFA4 OS=Homo sapiens OX=9606 GN=NDUFA4 PE=1 SV=1 4.21 3807.6 - 218991 - - - 0.0279 - 2.143 0.394 - 531 1 2 0 0 12 0 0 0 1.94E+06 2.90E+06 - - - 3.9566 0.9999 221125_WJC_METTL3_EV_vs_WT_F01.20739.20739.2 5.08E-06 24-Sep K.VLGTAFDPFLGGK.N "sp|Q92598|HS105_HUMAN,tr|A0A0A0MSM0|A0A0A0MSM0_HUMAN" 2 1320.7078 0.14 8154 20739 2 1320.707083 661.3612 Heat shock protein 105 kDa OS=Homo sapiens OX=9606 GN=HSPH1 PE=1 SV=1 5.81 3807.9 - 2.23E+06 - - - -0.5338 - 2.043 0.547 - 175.9 1 2 0 -0.0007 13 0 0 0 2.70E+07 1.98E+08 - - - 4.9145 0.9999 221125_WJC_METTL3_EV_vs_WT_F01.20743.20743.2 1.30E-06 14/34 K.ILDSFAAAPVPTTTLVLK[136.11].S sp|P18583|SON_HUMAN 1 1864.0801 -1 8158 20743 2 1864.079723 933.0473 Protein SON OS=Homo sapiens OX=9606 GN=SON PE=1 SV=4 5.84 3808.3 - 838466 - - - -0.2033 - 2.613 0.439 - 338.5 1 2 0 -0.0004 18 0 0 0 0.00E+00 0.00E+00 - - - 4.6448 0.997 221125_WJC_METTL3_EV_vs_WT_F01.20745.20745.3 0.254 Dec-40 R.QLLEEMLTSYR[166.11].L sp|O75688|PPM1B_HUMAN 1 1391.6994 2.85 8160 20745 3 1391.698698 464.9071 Protein phosphatase 1B OS=Homo sapiens OX=9606 GN=PPM1B PE=1 SV=1 4.53 3808.6 - 759944 - - - -0.5202 - 1.782 0.213 - 187.8 1 2 0 -0.0007 11 0 0 0 6.68E+06 2.34E+06 - - - 2.5558 0.9922 221125_WJC_METTL3_EV_vs_WT_F01.20751.20751.2 0.00176 14-Aug R.VFLWGSFR[166.11].D "sp|P18754|RCC1_HUMAN,tr|C9JQZ4|C9JQZ4_HUMAN,tr|C9J3R0|C9J3R0_HUMAN,tr|C9JMJ4|C9JMJ4_HUMAN,tr|C9JW69|C9JW69_HUMAN,tr|C9JRH2|C9JRH2_HUMAN" 6 1020.5421 0.66 8166 20751 2 1020.536995 511.2783 Regulator of chromosome condensation OS=Homo sapiens OX=9606 GN=RCC1 PE=1 SV=1 9.72 3809.3 - 450087 - - - -4.9601 - 1.522 0.392 - 275.9 1 2 0 -0.0051 8 0 0 0 5.28E+06 7.99E+06 - - - 3.2015 0.9992 221125_WJC_METTL3_EV_vs_WT_F01.20752.20752.2 0.0159 20-Sep K.VPPPWLIAMQR.Y "sp|Q13435|SF3B2_HUMAN,tr|E9PPJ0|E9PPJ0_HUMAN,tr|H0YEX5|H0YEX5_HUMAN" 3 1306.722 1.08 8167 20752 2 1306.720572 654.3683 Splicing factor 3B subunit 2 OS=Homo sapiens OX=9606 GN=SF3B2 PE=1 SV=2 9.72 3809.5 - 424464 - - - -1.0913 - 1.651 0.324 - 279.6 1 2 0 -0.0014 11 0 0 0 1.79E+07 1.66E+07 - - - 2.79 1 221125_WJC_METTL3_EV_vs_WT_F01.20753.20753.2 0.000449 16/22 L.PTLEAVAALGNK[136.11].V "sp|Q12905|ILF2_HUMAN,tr|B4DY09|B4DY09_HUMAN,tr|X6R6Z1|X6R6Z1_HUMAN" 3 1190.675 3.05 8168 20753 2 1190.675428 596.3448 Interleukin enhancer-binding factor 2 OS=Homo sapiens OX=9606 GN=ILF2 PE=1 SV=2 6.43 3809.6 - 383581 - - - 0.3275 - 2.908 0.558 - 613.4 1 1 0 0.0004 12 0 0 0 4.47E+06 1.47E+06 - - - 5.9709 0.9666 221125_WJC_METTL3_EV_vs_WT_F01.20757.20757.2 0.165 20-Jun R.MNYSDAIVWLK[136.11].E sp|O43776|SYNC_HUMAN 1 1346.6784 3.37 8172 20757 2 1346.672326 674.3465 "Asparagine--tRNA ligase, cytoplasmic OS=Homo sapiens OX=9606 GN=NARS1 PE=1 SV=1" 5.59 3810.1 - 303732 - - - -4.517 - 1.28 0.257 - 122.8 1 2 0 -0.0061 11 0 0 0 4.04E+06 1.20E+06 - - - 1.6051 0.9998 221125_WJC_METTL3_EV_vs_WT_F01.20760.20760.2 0.00527 18-Oct R.MALLATVLGR[166.11].F "sp|P27708|PYR1_HUMAN,tr|F8VPD4|F8VPD4_HUMAN,tr|H7C2E4|H7C2E4_HUMAN" 3 1053.6244 0.51 8174 20760 2 1053.624148 527.8195 CAD protein OS=Homo sapiens OX=9606 GN=CAD PE=1 SV=3 9.5 3810.5 - 2.16E+06 - - - -0.2449 - 2.194 0.439 - 390.4 1 2 0 -0.0003 10 0 0 0 3.60E+06 7.04E+06 - - - 4.4766 1 221125_WJC_METTL3_EV_vs_WT_F01.20762.20762.3 0.00138 16/56 K.VSQEILELLNTTTAK[136.11].E "sp|Q86U44|MTA70_HUMAN,tr|H0YFV6|H0YFV6_HUMAN" 2 1666.9233 0.01 8176 20762 3 1666.923313 556.6484 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 4.53 3810.6 - 4.21E+06 - - - 0.0276 - 2.448 0.476 - 246.7 1 2 0 0 15 0 0 0 3.21E+05 2.45E+07 - - - 6.183 1 221125_WJC_METTL3_EV_vs_WT_F01.20765.20765.3 1.41E-05 18/68 K.ILDSFAAAPVPTTTLVLK.S sp|P18583|SON_HUMAN 1 1856.0659 1.79 8179 20765 3 1856.067768 619.6959 Protein SON OS=Homo sapiens OX=9606 GN=SON PE=1 SV=4 5.84 3810.9 - 2.82E+06 - - - 1.0054 - 2.81 0.525 - 325.6 1 2 0 0.0019 18 0 0 0 6.17E+06 3.46E+06 - - - 6.9654 0.996 221125_WJC_METTL3_EV_vs_WT_F01.20766.20766.2 0.0796 14-Aug R.TLFGFLGK.L "sp|Q05519|SRS11_HUMAN,tr|S4R3C4|S4R3C4_HUMAN,tr|Q5T760|Q5T760_HUMAN,tr|B4DWT1|B4DWT1_HUMAN" 4 881.5011 1.49 8180 20766 2 881.501775 441.7578 Serine\arginine-rich splicing factor 11 OS=Homo sapiens OX=9606 GN=SRSF11 PE=1 SV=1 8.41 3811 - 2.59E+06 - - - 0.7771 - 1.154 0.261 - 178.9 1 2 0 0.0007 8 0 0 0 2.73E+07 1.84E+07 - - - 1.4005 0.9994 221125_WJC_METTL3_EV_vs_WT_F01.20767.20767.2 0.00886 14-Jul R.TLFGFLGK[136.11].L "sp|Q05519|SRS11_HUMAN,tr|S4R3C4|S4R3C4_HUMAN,tr|Q5T760|Q5T760_HUMAN,tr|B4DWT1|B4DWT1_HUMAN" 4 889.5153 1.49 8181 20767 2 889.515106 445.7649 Serine\arginine-rich splicing factor 11 OS=Homo sapiens OX=9606 GN=SRSF11 PE=1 SV=1 8.41 3811 - 2.42E+06 - - - -0.2069 - 1.495 0.358 - 142.8 1 2 0 -0.0002 8 0 0 0 2.73E+07 1.84E+07 - - - 2.8979 1 221125_WJC_METTL3_EV_vs_WT_F01.20768.20768.2 9.22E-09 18/30 R.LIADLGSTSITNLGFR.D sp|Q92520|FAM3C_HUMAN 1 1676.9097 1.21 8182 20768 2 1676.908705 839.4621 Protein FAM3C OS=Homo sapiens OX=9606 GN=FAM3C PE=1 SV=1 5.84 3811.2 - 1.94E+06 - - - -0.6142 - 3.439 0.589 - 973.3 1 2 0 -0.001 16 0 0 0 7.29E+06 6.04E+06 - - - 6.4278 1 221125_WJC_METTL3_EV_vs_WT_F01.20769.20769.3 3.40E-08 15/68 K.ILDSFAAAPVPTTTLVLK[136.11].S sp|P18583|SON_HUMAN 1 1864.0801 1.79 8183 20769 3 1864.079943 622.3673 Protein SON OS=Homo sapiens OX=9606 GN=SON PE=1 SV=4 5.84 3811.2 - 1.50E+06 - - - -0.0853 - 2.485 0.55 - 216.7 1 2 0 -0.0002 18 0 0 0 6.17E+06 3.46E+06 - - - 6.9386 0.9998 221125_WJC_METTL3_EV_vs_WT_F01.20770.20770.2 0.00201 18-Sep R.MALLATVLGR.F "sp|P27708|PYR1_HUMAN,tr|F8VPD4|F8VPD4_HUMAN,tr|H7C2E4|H7C2E4_HUMAN" 3 1043.6161 0.51 8184 20770 2 1043.616295 522.8153 CAD protein OS=Homo sapiens OX=9606 GN=CAD PE=1 SV=3 9.5 3811.4 - 1.32E+06 - - - 0.1524 - 2.131 0.419 - 198.6 1 2 0 0.0002 10 0 0 0 3.60E+06 7.04E+06 - - - 4.2476 1 221125_WJC_METTL3_EV_vs_WT_F01.20772.20772.2 5.27E-08 17/28 R.LISEILSESVVPDVR.S "sp|Q969G3|SMCE1_HUMAN,tr|A0A2R8Y855|A0A2R8Y855_HUMAN,tr|A0A2R8YES3|A0A2R8YES3_HUMAN,tr|A0A2U3TZQ7|A0A2U3TZQ7_HUMAN,tr|A0A2R8Y7U4|A0A2R8Y7U4_HUMAN,tr|B4DGM3|B4DGM3_HUMAN,tr|J3QKS7|J3QKS7_HUMAN,tr|A0A2R8Y4T4|A0A2R8Y4T4_HUMAN,tr|A0A2R8Y7I9|A0A2R8Y7I9_HUMAN,tr|J3QR61|J3QR61_HUMAN,tr|A0A2R8Y765|A0A2R8Y765_HUMAN" 11 1654.9142 -1 8186 20772 2 1654.913476 828.4644 SWI\SNF-related matrix-associated actin-dependent regulator of chromatin subfamily E member 1 OS=Homo sapiens OX=9606 GN=SMARCE1 PE=1 SV=2 4.14 3811.6 - 1.10E+06 - - - -0.4085 - 3.104 0.628 - 938.8 1 2 0 -0.0007 15 0 0 0 0.00E+00 0.00E+00 - - - 6.464 0.9989 221125_WJC_METTL3_EV_vs_WT_F01.20773.20773.2 0.287 20-Nov K.VPPPWLIAMQR[166.11].Y "sp|Q13435|SF3B2_HUMAN,tr|E9PPJ0|E9PPJ0_HUMAN,tr|H0YEX5|H0YEX5_HUMAN" 3 1316.7303 1.09 8187 20773 2 1316.730267 659.3724 Splicing factor 3B subunit 2 OS=Homo sapiens OX=9606 GN=SF3B2 PE=1 SV=2 9.72 3811.7 - 1.10E+06 - - - -0.0008 - 1.753 0.229 - 442.4 1 2 0 0 11 0 0 0 1.87E+07 1.72E+07 - - - 2.2509 0.9999 221125_WJC_METTL3_EV_vs_WT_F01.20775.20775.2 4.64E-05 24-Dec K.NIPMTLELLQSTR.L "sp|P23193|TCEA1_HUMAN,tr|E5RJ93|E5RJ93_HUMAN,tr|A0A1W2PPZ5|A0A1W2PPZ5_HUMAN,tr|E5RIS7|E5RIS7_HUMAN" 4 1514.8127 1.16 8189 20775 2 1514.812924 758.4136 Transcription elongation factor A protein 1 OS=Homo sapiens OX=9606 GN=TCEA1 PE=1 SV=2 6 3812 - 886349 - - - 0.1716 - 2.267 0.504 - 433.6 1 2 0 0.0003 13 0 0 0 4.99E+06 4.31E+06 - - - 4.8641 0.9998 221125_WJC_METTL3_EV_vs_WT_F01.20776.20776.2 0.00289 13/22 K.LVTLPVSFAQLK[136.11].N sp|Q96AG4|LRC59_HUMAN 1 1322.8053 1.22 8190 20776 2 1322.804127 662.4099 Leucine-rich repeat-containing protein 59 OS=Homo sapiens OX=9606 GN=LRRC59 PE=1 SV=1 8.75 3812.1 - 839962 - - - -0.9049 - 2.254 0.441 - 602.1 1 2 0 -0.0012 12 0 0 0 6.05E+07 4.98E+07 - - - 4.4362 0.9998 221125_WJC_METTL3_EV_vs_WT_F01.20777.20777.2 3.05E-05 24-Nov K.NIPMTLELLQSTR[166.11].L "sp|P23193|TCEA1_HUMAN,tr|E5RJ93|E5RJ93_HUMAN,tr|A0A1W2PPZ5|A0A1W2PPZ5_HUMAN,tr|E5RIS7|E5RIS7_HUMAN" 4 1524.8209 -1 8191 20777 2 1524.819254 763.4177 Transcription elongation factor A protein 1 OS=Homo sapiens OX=9606 GN=TCEA1 PE=1 SV=2 6 3812.2 - 826966 - - - -1.1018 - 2.097 0.466 - 310.2 1 2 0 -0.0017 13 0 0 0 0.00E+00 0.00E+00 - - - 4.3829 0.9999 221125_WJC_METTL3_EV_vs_WT_F01.20779.20779.2 9.57E-06 20-Dec K.VAVFFGGLSIK[136.11].K "sp|Q13838|DX39B_HUMAN,tr|A0A140TA18|A0A140TA18_HUMAN,tr|F6UJC5|F6UJC5_HUMAN,tr|F6TRA5|F6TRA5_HUMAN,tr|F6WLT2|F6WLT2_HUMAN,tr|Q5STU3|Q5STU3_HUMAN,tr|A0A140T973|A0A140T973_HUMAN,tr|A0A140T9K2|A0A140T9K2_HUMAN,tr|A0A140T9X9|A0A140T9X9_HUMAN,tr|F6R6M7|F6R6M7_HUMAN,tr|F6QYI9|F6QYI9_HUMAN,tr|A0A140T996|A0A140T996_HUMAN,tr|A0A0G2JJL7|A0A0G2JJL7_HUMAN,tr|A0A140T9L4|A0A140T9L4_HUMAN,tr|A0A140T9N3|A0A140T9N3_HUMAN,tr|A0A0G2JJZ9|A0A0G2JJZ9_HUMAN,tr|A0A140T9K1|A0A140T9K1_HUMAN,tr|A0A140T9X3|A0A140T9X3_HUMAN,tr|F6S4E6|F6S4E6_HUMAN,tr|A0A0A0MT12|A0A0A0MT12_HUMAN" 20 1144.6736 1.18 8193 20779 2 1144.67365 573.3441 Spliceosome RNA helicase DDX39B OS=Homo sapiens OX=9606 GN=DDX39B PE=1 SV=1 8.72 3812.5 - 656869 - - - 0.0603 - 2.158 0.551 - 439.4 1 2 0 0.0001 11 0 0 0 4.38E+06 3.70E+06 - - - 5.1915 0.9997 221125_WJC_METTL3_EV_vs_WT_F01.20781.20781.2 4.59E-05 20-Nov K.VAVFFGGLSIK.K "sp|Q13838|DX39B_HUMAN,tr|A0A140TA18|A0A140TA18_HUMAN,tr|F6UJC5|F6UJC5_HUMAN,tr|F6TRA5|F6TRA5_HUMAN,tr|F6WLT2|F6WLT2_HUMAN,tr|Q5STU3|Q5STU3_HUMAN,tr|A0A140T973|A0A140T973_HUMAN,tr|A0A140T9K2|A0A140T9K2_HUMAN,tr|A0A140T9X9|A0A140T9X9_HUMAN,tr|F6R6M7|F6R6M7_HUMAN,tr|F6QYI9|F6QYI9_HUMAN,tr|A0A140T996|A0A140T996_HUMAN,tr|A0A0G2JJL7|A0A0G2JJL7_HUMAN,tr|A0A140T9L4|A0A140T9L4_HUMAN,tr|A0A140T9N3|A0A140T9N3_HUMAN,tr|A0A0G2JJZ9|A0A0G2JJZ9_HUMAN,tr|A0A140T9K1|A0A140T9K1_HUMAN,tr|A0A140T9X3|A0A140T9X3_HUMAN,tr|F6S4E6|F6S4E6_HUMAN,tr|A0A0A0MT12|A0A0A0MT12_HUMAN" 20 1136.6594 1.25 8194 20781 2 1136.661251 569.337 Spliceosome RNA helicase DDX39B OS=Homo sapiens OX=9606 GN=DDX39B PE=1 SV=1 8.72 3812.7 - 924124 - - - 1.6452 - 2.334 0.417 - 431 1 2 0 0.0019 11 0 0 0 4.62E+06 3.70E+06 - - - 4.4133 0.9995 221125_WJC_METTL3_EV_vs_WT_F01.20782.20782.2 0.00207 20-Sep K.VSVFFGGLSIK.K "sp|O00148|DX39A_HUMAN,tr|K7EQN7|K7EQN7_HUMAN,tr|A0A0D9SEM9|A0A0D9SEM9_HUMAN" 3 1152.6543 0.63 8195 20782 2 1152.653374 577.3344 ATP-dependent RNA helicase DDX39A OS=Homo sapiens OX=9606 GN=DDX39A PE=1 SV=2 8.72 3812.8 - 456608 - - - -0.7999 - 1.693 0.348 - 182.3 1 2 0 -0.0009 11 0 0 0 5.29E+06 8.42E+06 - - - 3.0354 0.9999 221125_WJC_METTL3_EV_vs_WT_F01.20783.20783.2 0.000202 22-Oct K.LVTLPVSFAQLK.N sp|Q96AG4|LRC59_HUMAN 1 1314.7911 1.22 8196 20783 2 1314.790224 658.4028 Leucine-rich repeat-containing protein 59 OS=Homo sapiens OX=9606 GN=LRRC59 PE=1 SV=1 8.75 3812.9 - 4.61E+06 - - - -0.6845 - 1.989 0.511 - 344.5 1 2 0 -0.0009 12 0 0 0 6.05E+07 4.98E+07 - - - 4.6242 0.7943 221125_WJC_METTL3_EV_vs_WT_F01.20784.20784.2 1.77 24-Apr K.SAEAGIAGEAQSK.K "sp|Q7Z478|DHX29_HUMAN,tr|A0A087WYN9|A0A087WYN9_HUMAN" 2 1217.5888 32.36 8197 20784 2 1217.591542 609.8017 ATP-dependent RNA helicase DHX29 OS=Homo sapiens OX=9606 GN=DHX29 PE=1 SV=2 4.53 3812.9 - 2.74E+06 - - - 2.2561 - 1.142 0.07 - 24.7 36 2 0 0.0027 13 0 0 0 1.42E+07 4.38E+05 - - - -0.7973 0.9998 221125_WJC_METTL3_EV_vs_WT_F01.20785.20785.2 0.0109 16-Nov K.TLDDLFPLR[166.11].S "sp|Q8IZH2|XRN1_HUMAN,tr|H7C5E4|H7C5E4_HUMAN" 2 1098.5949 0.83 8198 20785 2 1098.594692 550.3047 5'-3' exoribonuclease 1 OS=Homo sapiens OX=9606 GN=XRN1 PE=1 SV=1 4.21 3813 - 2.00E+06 - - - -0.1711 - 2.028 0.39 - 399.6 1 2 0 -0.0002 9 0 0 0 1.19E+07 1.42E+07 - - - 3.967 1 221125_WJC_METTL3_EV_vs_WT_F01.20786.20786.2 3.82E-09 17/30 R.LIADLGSTSITNLGFR[166.11].D sp|Q92520|FAM3C_HUMAN 1 1686.918 -1 8199 20786 2 1686.916477 844.4663 Protein FAM3C OS=Homo sapiens OX=9606 GN=FAM3C PE=1 SV=1 5.84 3813.1 - 1.42E+06 - - - -0.9058 - 3.47 0.64 - 893.3 1 2 0 -0.0015 16 0 0 0 0.00E+00 0.00E+00 - - - 6.8264 0.9382 221125_WJC_METTL3_EV_vs_WT_F01.20787.20787.2 0.0529 18-Aug K.ASGATILSTL.A "sp|P17987|TCPA_HUMAN,tr|F5GZ03|F5GZ03_HUMAN,tr|F5H282|F5H282_HUMAN,tr|E7EQR6|E7EQR6_HUMAN,tr|E7ERF2|E7ERF2_HUMAN" 5 932.5179 - 8200 20787 2 932.517391 467.2662 T-complex protein 1 subunit alpha OS=Homo sapiens OX=9606 GN=TCP1 PE=1 SV=1 5.57 3813.2 - 1.37E+06 - - - -0.5051 - 1.327 0.336 - 156.4 1 1 0 -0.0005 10 0 0 0 - - - - - 2.3123 0.9908 221125_WJC_METTL3_EV_vs_WT_F01.20788.20788.2 5.63E-05 Dec-32 R.VETGVLK[136.11]PGMVVTFAPV.N "sp|P68104|EF1A1_HUMAN,sp|Q5VTE0|EF1A3_HUMAN,tr|A0A7I2V659|A0A7I2V659_HUMAN,tr|A0A7I2V3H3|A0A7I2V3H3_HUMAN,tr|A0A7I2V5N4|A0A7I2V5N4_HUMAN,tr|A0A087WVQ9|A0A087WVQ9_HUMAN" 6 1750.9783 0.35 8201 20788 2 1750.976472 876.4964 Elongation factor 1-alpha 1 OS=Homo sapiens OX=9606 GN=EEF1A1 PE=1 SV=1 5.97 3813.4 - 1.13E+06 - - - -1.032 - 2.335 0.492 - 178.2 1 1 0 -0.0018 17 0 0 0 1.72E+06 4.93E+06 - - - 4.7592 0.9998 221125_WJC_METTL3_EV_vs_WT_F01.20790.20790.3 8.89E-05 16/56 R.LISEILSESVVPDVR.S "sp|Q969G3|SMCE1_HUMAN,tr|A0A2R8Y855|A0A2R8Y855_HUMAN,tr|A0A2R8YES3|A0A2R8YES3_HUMAN,tr|A0A2U3TZQ7|A0A2U3TZQ7_HUMAN,tr|A0A2R8Y7U4|A0A2R8Y7U4_HUMAN,tr|B4DGM3|B4DGM3_HUMAN,tr|J3QKS7|J3QKS7_HUMAN,tr|A0A2R8Y4T4|A0A2R8Y4T4_HUMAN,tr|A0A2R8Y7I9|A0A2R8Y7I9_HUMAN,tr|J3QR61|J3QR61_HUMAN,tr|A0A2R8Y765|A0A2R8Y765_HUMAN" 11 1654.9142 -1 8203 20790 3 1654.914063 552.6453 SWI\SNF-related matrix-associated actin-dependent regulator of chromatin subfamily E member 1 OS=Homo sapiens OX=9606 GN=SMARCE1 PE=1 SV=2 4.14 3813.6 - 895323 - - - -0.0538 - 2.469 0.326 - 296.8 1 2 0 -0.0001 15 0 0 0 0.00E+00 0.00E+00 - - - 4.5329 1 221125_WJC_METTL3_EV_vs_WT_F01.20792.20792.3 2.45E-07 14/60 R.LIADLGSTSITNLGFR.D sp|Q92520|FAM3C_HUMAN 1 1676.9097 -1 8205 20792 3 1676.906862 559.9772 Protein FAM3C OS=Homo sapiens OX=9606 GN=FAM3C PE=1 SV=1 5.84 3813.9 - 719817 - - - -1.7133 - 2.542 0.509 - 235.1 1 2 0 -0.0029 16 0 0 0 0.00E+00 0.00E+00 - - - 6.6079 0.9741 221125_WJC_METTL3_EV_vs_WT_F01.20795.20795.2 1.96E-05 Nov-32 R.VETGVLKPGMVVTFAPV.N "sp|P68104|EF1A1_HUMAN,sp|Q5VTE0|EF1A3_HUMAN,tr|A0A7I2V659|A0A7I2V659_HUMAN,tr|A0A7I2V3H3|A0A7I2V3H3_HUMAN,tr|A0A7I2V5N4|A0A7I2V5N4_HUMAN,tr|A0A087WVQ9|A0A087WVQ9_HUMAN" 6 1742.9641 -1 8208 20795 2 1742.962606 872.4893 Elongation factor 1-alpha 1 OS=Homo sapiens OX=9606 GN=EEF1A1 PE=1 SV=1 5.97 3814.2 - 500336 - - - -0.8451 - 1.998 0.343 - 160.9 1 1 0 -0.0015 17 0 0 0 0.00E+00 0.00E+00 - - - 3.2756 0.9858 221125_WJC_METTL3_EV_vs_WT_F01.20796.20796.2 0.00237 22-Aug T.FSQTIALLNIYR[166.11].N sp|Q01081|U2AF1_HUMAN 1 1447.8063 -1 8209 20796 2 1447.806098 724.9104 Splicing factor U2AF 35 kDa subunit OS=Homo sapiens OX=9606 GN=U2AF1 PE=1 SV=3 8.75 3814.4 - 326740 - - - -0.1188 - 1.849 0.43 - 195.2 1 1 0 -0.0002 12 0 0 0 0.00E+00 0.00E+00 - - - 3.8342 1 221125_WJC_METTL3_EV_vs_WT_F01.20797.20797.3 3.31E-08 14/40 K.VPPPWLIAMQR.Y "sp|Q13435|SF3B2_HUMAN,tr|E9PPJ0|E9PPJ0_HUMAN,tr|H0YEX5|H0YEX5_HUMAN" 3 1306.722 0.78 8210 20797 3 1306.720823 436.5813 Splicing factor 3B subunit 2 OS=Homo sapiens OX=9606 GN=SF3B2 PE=1 SV=2 9.72 3814.5 - 320313 - - - -0.8992 - 2.783 0.57 - 386.6 1 2 0 -0.0012 11 0 0 0 2.30E+06 2.96E+06 - - - 7.8023 0.8792 221125_WJC_METTL3_EV_vs_WT_F01.20798.20798.2 0.696 22-Jun T.FSQTIALLNIYR.N sp|Q01081|U2AF1_HUMAN 1 1437.798 2.13 8211 20798 2 1437.798675 719.9063 Splicing factor U2AF 35 kDa subunit OS=Homo sapiens OX=9606 GN=U2AF1 PE=1 SV=3 8.75 3814.6 - 198300 - - - 0.4695 - 1.592 0.201 - 147.3 1 1 0 0.0007 12 0 0 0 1.74E+06 8.19E+05 - - - 1.7488 0.9811 221125_WJC_METTL3_EV_vs_WT_F01.20799.20799.2 0.0023 20-Oct K.VLYVYDMLAGK[136.11].L "sp|Q9Y5J1|UTP18_HUMAN,tr|J3KSR7|J3KSR7_HUMAN" 2 1278.6773 -1 8212 20799 2 1278.666904 640.3459 U3 small nucleolar RNA-associated protein 18 homolog OS=Homo sapiens OX=9606 GN=UTP18 PE=1 SV=3 5.8 3814.7 - 188751 - - - -8.1663 - 2.183 0.47 - 307.2 1 2 0 -0.0104 11 0 0 0 0.00E+00 0.00E+00 - - - 4.6211 0.9998 221125_WJC_METTL3_EV_vs_WT_F01.20800.20800.2 4.50E-06 26-Dec K.NLPIYSEEIVEMYK[136.11].G "sp|P35579|MYH9_HUMAN,tr|Q5BKV1|Q5BKV1_HUMAN" 2 1734.863 1.22 8213 20800 2 1734.866391 868.4388 Myosin-9 OS=Homo sapiens OX=9606 GN=MYH9 PE=1 SV=4 4.25 3814.9 - 184698 - - - 1.969 - 2.561 0.559 - 310.8 1 2 0 0.0034 14 0 0 0 4.54E+06 3.72E+06 - - - 5.5286 1 221125_WJC_METTL3_EV_vs_WT_F01.20805.20805.2 8.72E-08 16/28 K.VSQEILELLNTTTAK[136.11].E "sp|Q86U44|MTA70_HUMAN,tr|H0YFV6|H0YFV6_HUMAN" 2 1666.9233 0 8217 20805 2 1666.919821 834.4689 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 4.53 3815.3 - 4.45E+06 - - - -2.0673 - 3.01 0.573 - 1072.3 1 2 0 -0.0034 15 0 0 0 8.48E+04 2.17E+07 - - - 5.9813 0.9999 221125_WJC_METTL3_EV_vs_WT_F01.20809.20809.3 0.000182 Nov-44 K.LVTLPVSFAQLK.N sp|Q96AG4|LRC59_HUMAN 1 1314.7911 1.41 8221 20809 3 1314.789199 439.271 Leucine-rich repeat-containing protein 59 OS=Homo sapiens OX=9606 GN=LRRC59 PE=1 SV=1 8.75 3815.7 - 888602 - - - -1.4641 - 2.144 0.474 - 234.5 1 2 0 -0.0019 12 0 0 0 3.40E+06 2.40E+06 - - - 5.9381 1 221125_WJC_METTL3_EV_vs_WT_F01.20811.20811.2 3.21E-08 26-Dec K.NLPIYSEEIVEMYK.G "sp|P35579|MYH9_HUMAN,tr|Q5BKV1|Q5BKV1_HUMAN" 2 1726.8488 1.45 8223 20811 2 1726.84729 864.4317 Myosin-9 OS=Homo sapiens OX=9606 GN=MYH9 PE=1 SV=4 4.25 3815.9 - 691396 - - - -0.8599 - 2.752 0.622 - 350.3 1 2 0 -0.0015 14 0 0 0 5.51E+06 3.79E+06 - - - 6.175 0.9985 221125_WJC_METTL3_EV_vs_WT_F01.20812.20812.2 0.4 14-Sep K.VALLDVFR[166.11].E "sp|P25205|MCM3_HUMAN,tr|J3KQ69|J3KQ69_HUMAN,tr|A0A499FHX9|A0A499FHX9_HUMAN" 3 941.5574 0.52 8224 20812 2 941.55568 471.786 DNA replication licensing factor MCM3 OS=Homo sapiens OX=9606 GN=MCM3 PE=1 SV=3 5.81 3816.1 - 683110 - - - -1.797 - 1.933 0.211 - 411 1 2 0 -0.0017 8 0 0 0 2.39E+07 4.59E+07 - - - 2.5866 1 221125_WJC_METTL3_EV_vs_WT_F01.20813.20813.2 9.66E-07 14/24 R.LGSTIFVANLDFK[136.11].V "sp|Q9P2K5|MYEF2_HUMAN,tr|A0A0A0MR39|A0A0A0MR39_HUMAN,tr|A0A087WUT0|A0A087WUT0_HUMAN,tr|H0YN19|H0YN19_HUMAN,tr|A0A0A0MQW0|A0A0A0MQW0_HUMAN" 5 1431.7853 2.18 8225 20813 2 1431.782908 716.8999 Myelin expression factor 2 OS=Homo sapiens OX=9606 GN=MYEF2 PE=1 SV=3 5.84 3816.2 - 638554 - - - -1.6825 - 3.204 0.516 - 776.1 1 2 0 -0.0024 13 0 0 0 4.95E+06 2.27E+06 - - - 5.8399 0.9999 221125_WJC_METTL3_EV_vs_WT_F01.20815.20815.2 1.02E-07 24-Nov R.LGSTIFVANLDFK.V "sp|Q9P2K5|MYEF2_HUMAN,tr|A0A0A0MR39|A0A0A0MR39_HUMAN,tr|A0A087WUT0|A0A087WUT0_HUMAN,tr|H0YN19|H0YN19_HUMAN,tr|A0A0A0MQW0|A0A0A0MQW0_HUMAN" 5 1423.7711 1.29 8227 20815 2 1423.769227 712.8928 Myelin expression factor 2 OS=Homo sapiens OX=9606 GN=MYEF2 PE=1 SV=3 5.84 3816.5 - 587975 - - - -1.3275 - 2.636 0.536 - 426.6 1 2 0 -0.0019 13 0 0 0 2.92E+06 2.27E+06 - - - 5.4869 0.9756 221125_WJC_METTL3_EV_vs_WT_F01.20816.20816.3 0.134 Sep-36 R.ELYLLFR[166.11]PFK[136.11].G "sp|Q6ZRY4|RBPS2_HUMAN,sp|Q93062|RBPMS_HUMAN,tr|H0YBU9|H0YBU9_HUMAN,tr|B4E3T4|B4E3T4_HUMAN" 4 1342.7768 1.47 8228 20816 3 1342.773895 448.5995 RNA-binding protein with multiple splicing 2 OS=Homo sapiens OX=9606 GN=RBPMS2 PE=1 SV=1 8.69 3816.6 - 392623 - - - -2.1739 - 1.883 0.117 - 96.2 1 2 0 -0.0029 10 0 0 0 1.79E+06 1.21E+06 - - - 1.6919 0.9996 221125_WJC_METTL3_EV_vs_WT_F01.20818.20818.2 0.000736 22-Aug K.EEIFGPVQPLFK[136.11].F sp|P30837|AL1B1_HUMAN 1 1410.7639 -1 8230 20818 2 1410.762697 706.3892 "Aldehyde dehydrogenase X, mitochondrial OS=Homo sapiens OX=9606 GN=ALDH1B1 PE=1 SV=3" 4.53 3816.9 - 348981 - - - -0.8194 - 1.643 0.402 - 223.9 1 2 0 -0.0012 12 0 0 0 0.00E+00 0.00E+00 - - - 3.3162 0.9998 221125_WJC_METTL3_EV_vs_WT_F01.20824.20824.2 2.45E-06 Nov-34 K.IGIIGGTGLDDPEILEGR[166.11].T "sp|Q13126|MTAP_HUMAN,tr|B4DUC8|B4DUC8_HUMAN,tr|F2Z2F3|F2Z2F3_HUMAN,tr|F8WES2|F8WES2_HUMAN,tr|J3QSB7|J3QSB7_HUMAN" 5 1833.9712 -1 8235 20824 2 1833.967912 917.9929 S-methyl-5'-thioadenosine phosphorylase OS=Homo sapiens OX=9606 GN=MTAP PE=1 SV=2 3.92 3817.7 - 138951 - - - -1.7727 - 2.168 0.513 - 229.2 1 2 0 -0.0033 18 0 0 0 0.00E+00 0.00E+00 - - - 4.7314 0.9997 221125_WJC_METTL3_EV_vs_WT_F01.20825.20825.2 0.0823 14-Sep K.VALLDVFR.E "sp|P25205|MCM3_HUMAN,tr|J3KQ69|J3KQ69_HUMAN,tr|A0A499FHX9|A0A499FHX9_HUMAN" 3 931.5491 0.52 8236 20825 2 931.548483 466.7818 DNA replication licensing factor MCM3 OS=Homo sapiens OX=9606 GN=MCM3 PE=1 SV=3 5.81 3817.7 - 2.40E+06 - - - -0.6645 - 2.01 0.326 - 399 1 2 0 -0.0006 8 0 0 0 2.39E+07 4.59E+07 - - - 3.5542 0.9999 221125_WJC_METTL3_EV_vs_WT_F01.20827.20827.2 3.71E-06 20-Oct K.VLYVYDMLAGK.L "sp|Q9Y5J1|UTP18_HUMAN,tr|J3KSR7|J3KSR7_HUMAN" 2 1270.6631 1.14 8238 20827 2 1270.663246 636.3388 U3 small nucleolar RNA-associated protein 18 homolog OS=Homo sapiens OX=9606 GN=UTP18 PE=1 SV=3 5.8 3817.9 - 1.32E+06 - - - 0.0787 - 1.855 0.533 - 351.3 1 2 0 0.0001 11 0 0 0 2.81E+06 2.46E+06 - - - 4.6492 0.9995 221125_WJC_METTL3_EV_vs_WT_F01.20829.20829.2 0.0522 14-Sep R.IPFTFWAR.Y sp|Q9Y5V3|MAGD1_HUMAN 1 1036.5494 1.23 8240 20829 2 1036.549034 519.282 Melanoma-associated antigen D1 OS=Homo sapiens OX=9606 GN=MAGED1 PE=1 SV=3 9.75 3818.2 - 1.14E+06 - - - -0.3888 - 1.607 0.345 - 354.2 1 2 0 -0.0004 8 0 0 0 1.20E+07 9.71E+06 - - - 3.0197 0.9999 221125_WJC_METTL3_EV_vs_WT_F01.20831.20831.2 0.000267 20-Oct R.TSLGNVVLLLK.S "sp|O60231|DHX16_HUMAN,tr|Q5SQH5|Q5SQH5_HUMAN,tr|A0A140T8Y5|A0A140T8Y5_HUMAN" 3 1155.7227 1.51 8242 20831 2 1155.722225 578.8686 Pre-mRNA-splicing factor ATP-dependent RNA helicase DHX16 OS=Homo sapiens OX=9606 GN=DHX16 PE=1 SV=2 8.41 3818.4 - 860651 - - - -0.4197 - 2.265 0.455 - 255.9 1 2 0 -0.0005 11 0 0 0 1.33E+07 8.79E+06 - - - 4.6132 0.9999 221125_WJC_METTL3_EV_vs_WT_F01.20833.20833.3 0.000682 Nov-44 R.LFPPQWIC[160.03]C[160.03]DIR.Y sp|Q86U44|MTA70_HUMAN 1 1603.7639 0.02 8244 20833 3 1603.76557 535.5953 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 5.82 3818.7 - 630815 - - - 1.0164 - 2.132 0.427 - 126 1 2 0 0.0016 12 0 0 0 3.85E+06 2.08E+08 - - - 5.3986 0.9391 221125_WJC_METTL3_EV_vs_WT_F01.20834.20834.2 0.00111 18-Jul K.LDNLQQEIDF.L sp|P04264|K2C1_HUMAN 1 1233.5877 - 8245 20834 2 1233.585196 617.8011 "Keratin, type II cytoskeletal 1 OS=Homo sapiens OX=9606 GN=KRT1 PE=1 SV=6" 3.49 3818.8 - 530735 - - - -2.0566 - 1.455 0.403 - 172.4 1 1 0 -0.0025 10 0 0 0 - - - - - 3.0635 0.9999 221125_WJC_METTL3_EV_vs_WT_F01.20835.20835.2 6.33E-07 28-Dec K.TVAGQDAVIVLLGTR[166.11].N "sp|P30043|BLVRB_HUMAN,tr|A0A2R8YEP4|A0A2R8YEP4_HUMAN,tr|A0A2R8Y7Y9|A0A2R8Y7Y9_HUMAN,tr|M0R192|M0R192_HUMAN,tr|M0QZL1|M0QZL1_HUMAN" 5 1521.8754 0.93 8246 20835 2 1521.873445 761.945 Flavin reductase (NADPH) OS=Homo sapiens OX=9606 GN=BLVRB PE=1 SV=3 5.5 3818.9 - 431027 - - - -1.2925 - 2.427 0.581 - 358.5 1 2 0 -0.002 15 0 0 0 1.90E+06 2.05E+06 - - - 5.5115 0.9998 221125_WJC_METTL3_EV_vs_WT_F01.20836.20836.2 0.00622 22-Dec K.NFFYIISPGVTK.V sp|Q10472|GALT1_HUMAN 1 1384.7391 1.46 8247 20836 2 1384.736592 693.3768 Polypeptide N-acetylgalactosaminyltransferase 1 OS=Homo sapiens OX=9606 GN=GALNT1 PE=1 SV=1 8.59 3819.1 - 423981 - - - -1.8025 - 2.175 0.503 - 502 1 2 0 -0.0025 12 0 0 0 1.11E+07 7.57E+06 - - - 4.7999 0.9978 221125_WJC_METTL3_EV_vs_WT_F01.20837.20837.2 0.00326 14-Sep R.FPLFGGWK[136.11].T "sp|P04843|RPN1_HUMAN,tr|B7Z4L4|B7Z4L4_HUMAN" 2 958.5156 1.47 8248 20837 2 958.512489 480.2651 Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit 1 OS=Homo sapiens OX=9606 GN=RPN1 PE=1 SV=1 8.75 3819.2 - 328617 - - - -3.2707 - 1.725 0.346 - 312.9 1 2 0 -0.0031 8 0 0 0 3.36E+07 2.29E+07 - - - 3.24 0.9877 221125_WJC_METTL3_EV_vs_WT_F01.20839.20839.2 3.00E-07 26-Dec R.WEGPLSVSVFAATK.E sp|O43505|B4GA1_HUMAN 1 1490.7769 1.35 8250 20839 2 1490.789049 746.3957 "Beta-1,4-glucuronyltransferase 1 OS=Homo sapiens OX=9606 GN=B4GAT1 PE=1 SV=1" 6 3819.5 - 279004 - - - 8.1293 - 2.45 0.502 - 488.1 1 2 0 0.0121 14 0 0 0 2.25E+06 1.66E+06 - - - 4.9937 1 221125_WJC_METTL3_EV_vs_WT_F01.20843.20843.3 3.10E-07 Dec-44 R.LFPPQWIC[160.03]C[160.03]DIR[166.11].Y sp|Q86U44|MTA70_HUMAN 1 1613.7722 0.02 8253 20843 3 1613.770942 538.9313 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 5.82 3819.9 - 2.22E+07 - - - -0.7857 - 2.336 0.638 - 175 1 2 0 -0.0013 12 0 0 0 3.85E+06 2.08E+08 - - - 8.0045 1 221125_WJC_METTL3_EV_vs_WT_F01.20846.20846.2 2.80E-09 13/26 R.IVEPYIAWGYPNLK.S "sp|P18124|RL7_HUMAN,tr|A8MUD9|A8MUD9_HUMAN" 2 1661.8817 1.1 8255 20846 2 1661.879575 831.9481 60S ribosomal protein L7 OS=Homo sapiens OX=9606 GN=RPL7 PE=1 SV=1 6 3820.2 - 2.86E+06 - - - -1.2967 - 2.595 0.664 - 581 1 2 0 -0.0022 14 0 0 0 3.00E+07 2.73E+07 - - - 6.3376 0.9999 221125_WJC_METTL3_EV_vs_WT_F01.20847.20847.2 1.61E-07 13/26 R.IVEPYIAWGYPNLK[136.11].S "sp|P18124|RL7_HUMAN,tr|A8MUD9|A8MUD9_HUMAN" 2 1669.8959 1.1 8256 20847 2 1669.893964 835.9552 60S ribosomal protein L7 OS=Homo sapiens OX=9606 GN=RPL7 PE=1 SV=1 6 3820.3 - 3.06E+06 - - - -1.1773 - 2.39 0.583 - 563.1 1 2 0 -0.002 14 0 0 0 3.00E+07 2.73E+07 - - - 5.5329 0.9989 221125_WJC_METTL3_EV_vs_WT_F01.20848.20848.2 0.00135 14-Aug R.DFLLDIAR[166.11].Q "sp|Q9HBM6|TAF9B_HUMAN,sp|Q16594|TAF9_HUMAN,tr|D6RIE8|D6RIE8_HUMAN,tr|D6RIV9|D6RIV9_HUMAN,tr|D6RIY1|D6RIY1_HUMAN,tr|D6RGK3|D6RGK3_HUMAN,tr|D6RHW1|D6RHW1_HUMAN" 7 971.5316 1.22 8257 20848 2 971.530737 486.7731 Transcription initiation factor TFIID subunit 9B OS=Homo sapiens OX=9606 GN=TAF9B PE=1 SV=1 4.21 3820.3 - 1.91E+06 - - - -0.8389 - 1.53 0.278 - 308.9 1 2 0 -0.0008 8 0 0 0 2.47E+07 2.03E+07 - - - 2.3766 0.9999 221125_WJC_METTL3_EV_vs_WT_F01.20849.20849.2 4.25E-09 22-Dec K.NFFYIISPGVTK[136.11].V sp|Q10472|GALT1_HUMAN 1 1392.7533 1.46 8258 20849 2 1392.752902 697.3839 Polypeptide N-acetylgalactosaminyltransferase 1 OS=Homo sapiens OX=9606 GN=GALNT1 PE=1 SV=1 8.59 3820.4 - 1.13E+06 - - - -0.2771 - 2.231 0.598 - 513.4 1 2 0 -0.0004 12 0 0 0 1.11E+07 7.57E+06 - - - 5.5691 0.8064 221125_WJC_METTL3_EV_vs_WT_F01.20855.20855.2 0.0174 18-Jul R.DPTYFGPVLN.Y "sp|Q9NXV2|KCTD5_HUMAN,tr|H3BSS5|H3BSS5_HUMAN" 2 1121.5393 - 8264 20855 2 1121.53689 561.7769 BTB\POZ domain-containing protein KCTD5 OS=Homo sapiens OX=9606 GN=KCTD5 PE=1 SV=1 3.8 3821.2 - 467368 - - - -2.172 - 1.277 0.302 - 87 1 1 0 -0.0024 10 0 0 0 - - - - - 1.9533 0.9965 221125_WJC_METTL3_EV_vs_WT_F01.20856.20856.2 0.347 14-May R.EGLLAIFK[136.11].S "sp|P35222|CTNB1_HUMAN,sp|P14923|PLAK_HUMAN,tr|C9JKY1|C9JKY1_HUMAN,tr|A0A2R8Y5C3|A0A2R8Y5C3_HUMAN,tr|C9JK18|C9JK18_HUMAN,tr|A0A2R8YCH5|A0A2R8YCH5_HUMAN,tr|A0A2R8Y543|A0A2R8Y543_HUMAN,tr|A0A2R8Y750|A0A2R8Y750_HUMAN,tr|B4DGU4|B4DGU4_HUMAN,tr|C9JTX4|C9JTX4_HUMAN,tr|A0A2R8Y5A3|A0A2R8Y5A3_HUMAN,tr|A0A2R8Y804|A0A2R8Y804_HUMAN,tr|C9J826|C9J826_HUMAN,tr|A0A2R8Y5Z1|A0A2R8Y5Z1_HUMAN,tr|A0A2R8Y7Z0|A0A2R8Y7Z0_HUMAN" 15 897.5415 12.63 8265 20856 2 897.540212 449.778 Catenin beta-1 OS=Homo sapiens OX=9606 GN=CTNNB1 PE=1 SV=1 6.1 3821.3 - 344706 - - - -1.4395 - 1.308 0.246 - 72.5 1 2 0 -0.0013 8 0 0 0 2.76E+07 2.19E+06 - - - 1.6673 0.9697 221125_WJC_METTL3_EV_vs_WT_F01.20858.20858.2 1.74 18-Sep K.APDFLPLLNK.G sp|O75695|XRP2_HUMAN 1 1126.6386 0.63 8267 20858 2 1126.640954 564.3266 Protein XRP2 OS=Homo sapiens OX=9606 GN=RP2 PE=1 SV=4 5.88 3821.6 - 288382 - - - 2.0486 - 1.373 0.071 - 114.1 1 2 0 0.0023 10 0 0 0 2.22E+06 3.53E+06 - - - 0.4495 0.9998 221125_WJC_METTL3_EV_vs_WT_F01.20862.20862.2 0.00019 18-Nov K.APDFLPLLNK[136.11].G sp|O75695|XRP2_HUMAN 1 1134.6528 0.3 8271 20862 2 1134.653184 568.3337 Protein XRP2 OS=Homo sapiens OX=9606 GN=RP2 PE=1 SV=4 5.88 3822.1 - 177942 - - - 0.2979 - 1.734 0.461 - 274 1 2 0 0.0003 10 0 0 0 1.26E+06 4.17E+06 - - - 3.9823 0.9998 221125_WJC_METTL3_EV_vs_WT_F01.20863.20863.2 0.00208 24-Sep R.VIYAMAEDGLLFK[136.11].F "sp|P30825|SL7A1_HUMAN,sp|P52569|CTR2_HUMAN,tr|A0A1W2PR06|A0A1W2PR06_HUMAN" 3 1476.7778 0.65 8272 20863 2 1476.776878 739.3962 High affinity cationic amino acid transporter 1 OS=Homo sapiens OX=9606 GN=SLC7A1 PE=1 SV=1 4.37 3822.2 - 172779 - - - -0.6162 - 2.019 0.442 - 195.4 1 2 0 -0.0009 13 0 0 0 5.67E+05 8.67E+05 - - - 4.1086 0.9991 221125_WJC_METTL3_EV_vs_WT_F01.20864.20864.2 0.000634 24-Oct K.LLEQALVIEEQLR[166.11].R "sp|Q14839|CHD4_HUMAN,sp|Q8TDI0|CHD5_HUMAN,sp|Q12873|CHD3_HUMAN,tr|A0A2R8Y4X2|A0A2R8Y4X2_HUMAN,tr|A0A2U3TZM0|A0A2U3TZM0_HUMAN,tr|H7C0J3|H7C0J3_HUMAN,tr|A0A2R8YD40|A0A2R8YD40_HUMAN,tr|A0A2R8Y5J0|A0A2R8Y5J0_HUMAN,tr|A0A2R8Y425|A0A2R8Y425_HUMAN,tr|A0A2R8YFK9|A0A2R8YFK9_HUMAN,tr|A0A0C4DGG9|A0A0C4DGG9_HUMAN,tr|A0A2R8YFD8|A0A2R8YFD8_HUMAN,tr|A0A2R8YDW2|A0A2R8YDW2_HUMAN,tr|A0A2R8Y7I0|A0A2R8Y7I0_HUMAN,tr|F5GWX5|F5GWX5_HUMAN,tr|A0A2R8Y7M9|A0A2R8Y7M9_HUMAN,tr|I3L229|I3L229_HUMAN,tr|A0A2R8Y521|A0A2R8Y521_HUMAN,tr|A0A2R8YDJ9|A0A2R8YDJ9_HUMAN,tr|A0A2R8Y212|A0A2R8Y212_HUMAN,tr|H7C3H7|H7C3H7_HUMAN" 21 1562.8907 -1 8273 20864 2 1562.890497 782.4526 Chromodomain-helicase-DNA-binding protein 4 OS=Homo sapiens OX=9606 GN=CHD4 PE=1 SV=2 4.25 3822.4 - 166716 - - - -0.1478 - 1.589 0.297 - 268.4 1 2 0 -0.0002 13 0 0 0 0.00E+00 0.00E+00 - - - 2.4231 0.9999 221125_WJC_METTL3_EV_vs_WT_F01.20868.20868.2 1.48E-05 24-Nov K.AAILPTSIFLTNK.K "sp|O14744|ANM5_HUMAN,tr|H0YJX6|H0YJX6_HUMAN" 2 1387.8075 2.88 8276 20868 2 1387.807059 694.911 Protein arginine N-methyltransferase 5 OS=Homo sapiens OX=9606 GN=PRMT5 PE=1 SV=4 8.8 3822.8 - 9.63E+06 - - - -0.3192 - 2.244 0.483 - 308.7 1 2 0 -0.0004 13 0 0 0 1.22E+08 4.24E+07 - - - 4.6827 0.9989 221125_WJC_METTL3_EV_vs_WT_F01.20870.20870.2 0.0155 14-Aug R.FPLFGGWK.T "sp|P04843|RPN1_HUMAN,tr|B7Z4L4|B7Z4L4_HUMAN" 2 950.5014 1.43 8278 20870 2 950.50042 476.258 Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit 1 OS=Homo sapiens OX=9606 GN=RPN1 PE=1 SV=1 8.75 3822.9 - 2.39E+06 - - - -1.0563 - 1.505 0.294 - 235.2 1 2 0 -0.001 8 0 0 0 3.28E+07 2.29E+07 - - - 2.4451 0.9991 221125_WJC_METTL3_EV_vs_WT_F01.20871.20871.2 0.0504 20-Sep R.TSLGNVVLLLK[136.11].S "sp|O60231|DHX16_HUMAN,tr|Q5SQH5|Q5SQH5_HUMAN,tr|A0A140T8Y5|A0A140T8Y5_HUMAN" 3 1163.7369 1.5 8279 20871 2 1163.736342 582.8757 Pre-mRNA-splicing factor ATP-dependent RNA helicase DHX16 OS=Homo sapiens OX=9606 GN=DHX16 PE=1 SV=2 8.41 3822.9 - 2.33E+06 - - - -0.4881 - 1.732 0.265 - 195.1 1 2 0 -0.0006 11 0 0 0 1.32E+07 8.79E+06 - - - 2.484 0.9999 221125_WJC_METTL3_EV_vs_WT_F01.20872.20872.2 0.000639 18-Oct R.SDLVLLYELK[136.11].Q sp|Q9NPF5|DMAP1_HUMAN 1 1199.6893 1.89 8280 20872 2 1199.689201 600.8519 DNA methyltransferase 1-associated protein 1 OS=Homo sapiens OX=9606 GN=DMAP1 PE=1 SV=1 4.37 3823 - 2.18E+06 - - - -0.075 - 2.285 0.483 - 352.7 1 2 0 -0.0001 10 0 0 0 1.46E+07 7.70E+06 - - - 4.915 1 221125_WJC_METTL3_EV_vs_WT_F01.20874.20874.3 1.94E-06 14/48 K.AAILPTSIFLTNK.K "sp|O14744|ANM5_HUMAN,tr|H0YJX6|H0YJX6_HUMAN" 2 1387.8075 0.49 8282 20874 3 1387.806827 463.6098 Protein arginine N-methyltransferase 5 OS=Homo sapiens OX=9606 GN=PRMT5 PE=1 SV=4 8.8 3823.2 - 872024 - - - -0.4864 - 2.693 0.527 - 262.5 1 2 0 -0.0007 13 0 0 0 6.24E+06 1.27E+07 - - - 7.1013 0.9952 221125_WJC_METTL3_EV_vs_WT_F01.20879.20879.2 1.95E-07 20-Dec R.PLEVFMC[160.03]SVLK.R "sp|Q9Y6B6|SAR1B_HUMAN,tr|D6R9R5|D6R9R5_HUMAN,tr|Q9H029|Q9H029_HUMAN" 3 1321.6774 1.04 8287 20879 2 1321.677286 661.846 GTP-binding protein SAR1b OS=Homo sapiens OX=9606 GN=SAR1B PE=1 SV=1 6.38 3823.8 - 680289 - - - -0.0984 - 2.345 0.592 - 431.2 1 1 0 -0.0001 11 0 0 0 2.07E+06 1.98E+06 - - - 5.7191 0.991 221125_WJC_METTL3_EV_vs_WT_F01.20881.20881.2 0.0124 20-Nov R.PLEVFMC[160.03]SVLK[136.11].R "sp|Q9Y6B6|SAR1B_HUMAN,tr|D6R9R5|D6R9R5_HUMAN,tr|Q9H029|Q9H029_HUMAN" 3 1329.6916 1.7 8289 20881 2 1329.69053 665.8531 GTP-binding protein SAR1b OS=Homo sapiens OX=9606 GN=SAR1B PE=1 SV=1 6.38 3824.1 - 542495 - - - -0.8167 - 2.19 0.474 - 380.5 1 1 0 -0.0011 11 0 0 0 3.37E+06 1.98E+06 - - - 4.6623 0.9998 221125_WJC_METTL3_EV_vs_WT_F01.20882.20882.2 0.00265 24-Nov K.IAVPLIQGYTVLR.L sp|Q8IW92|GLBL2_HUMAN 1 1441.8657 1.38 8290 20882 2 1441.865235 721.9401 Beta-galactosidase-1-like protein 2 OS=Homo sapiens OX=9606 GN=GLB1L2 PE=1 SV=1 8.75 3824.2 - 299819 - - - -0.3128 - 2.146 0.383 - 404.5 1 2 0 -0.0005 13 0 0 0 2.86E+06 2.07E+06 - - - 3.8295 0.8707 221125_WJC_METTL3_EV_vs_WT_F01.20887.20887.2 2 14-Apr R.DSLIDSLT.- sp|P56537|IF6_HUMAN 1 862.4284 - 8293 20887 2 862.427484 432.2215 Eukaryotic translation initiation factor 6 OS=Homo sapiens OX=9606 GN=EIF6 PE=1 SV=1 3.56 3824.9 - 3.08E+06 - - - -1.0366 - 0.92 0.053 - 59.8 2 2 0 -0.0009 8 0 0 0 - - - - - -0.9538 0.9999 221125_WJC_METTL3_EV_vs_WT_F01.20888.20888.2 1.24E-07 30-Nov R.IASLPVEVQEVSLLDK.L "sp|Q96P16|RPR1A_HUMAN,tr|A0A0C4DGQ6|A0A0C4DGQ6_HUMAN,tr|K7EP82|K7EP82_HUMAN" 3 1738.9717 1.78 8294 20888 2 1738.970563 870.4931 Regulation of nuclear pre-mRNA domain-containing protein 1A OS=Homo sapiens OX=9606 GN=RPRD1A PE=1 SV=1 4.14 3824.9 - 1.78E+06 - - - -0.6349 - 2.268 0.565 - 265.3 1 2 0 -0.0011 16 0 0 0 1.28E+07 7.22E+06 - - - 5.227 0.9995 221125_WJC_METTL3_EV_vs_WT_F01.20889.20889.2 0.0114 18-Sep K.FSLFAGGMLR.V sp|Q9BVK6|TMED9_HUMAN 1 1097.5692 1.28 8295 20889 2 1097.568472 549.7919 Transmembrane emp24 domain-containing protein 9 OS=Homo sapiens OX=9606 GN=TMED9 PE=1 SV=2 9.75 3825 - 1.46E+06 - - - -0.6505 - 1.93 0.301 - 257.2 1 2 0 -0.0007 10 0 0 0 6.27E+06 4.90E+06 - - - 3.0993 1 221125_WJC_METTL3_EV_vs_WT_F01.20891.20891.2 9.84E-12 16/28 R.GFGFVTFADPASVDK[136.11].V "sp|Q96DH6|MSI2H_HUMAN,tr|B4DHE8|B4DHE8_HUMAN,tr|A0A6Q8PF05|A0A6Q8PF05_HUMAN,tr|J3QKT5|J3QKT5_HUMAN,tr|A0A6Q8PFU8|A0A6Q8PFU8_HUMAN,tr|J3KTC1|J3KTC1_HUMAN,tr|A0A6Q8PHT3|A0A6Q8PHT3_HUMAN" 7 1564.7653 1.88 8297 20891 2 1564.764371 783.3899 RNA-binding protein Musashi homolog 2 OS=Homo sapiens OX=9606 GN=MSI2 PE=1 SV=1 4.21 3825.2 - 973842 - - - -0.6001 - 2.839 0.711 - 794.7 1 2 0 -0.0009 15 0 0 0 2.35E+07 1.25E+07 - - - 6.8575 0.9963 221125_WJC_METTL3_EV_vs_WT_F01.20892.20892.2 0.00147 14-Sep K.FYSFLVLK[136.11].K "sp|Q9H4I0|RD21L_HUMAN,sp|O60216|RAD21_HUMAN,tr|A0A804HJ87|A0A804HJ87_HUMAN,tr|E5RI01|E5RI01_HUMAN,tr|E5RG18|E5RG18_HUMAN,tr|E5RFZ5|E5RFZ5_HUMAN" 6 1023.5885 1.34 8298 20892 2 1023.592337 512.8015 Double-strand-break repair protein rad21-like protein 1 OS=Homo sapiens OX=9606 GN=RAD21L1 PE=2 SV=3 8.59 3825.4 - 763483 - - - 3.7925 - 1.469 0.395 - 190.7 1 2 0 0.0039 8 0 0 0 8.08E+06 6.05E+06 - - - 3.1171 1 221125_WJC_METTL3_EV_vs_WT_F01.20894.20894.3 8.81E-07 15/56 K.VVLAYEPVWAIGTGK.T "sp|P60174|TPIS_HUMAN,tr|U3KQF3|U3KQF3_HUMAN,tr|U3KPZ0|U3KPZ0_HUMAN" 3 1601.8817 1.7 8300 20894 3 1601.88192 534.9679 Triosephosphate isomerase OS=Homo sapiens OX=9606 GN=TPI1 PE=1 SV=4 5.97 3825.5 - 660608 - - - 0.1186 - 2.462 0.498 - 348.3 1 2 0 0.0002 15 0 0 0 6.85E+06 4.02E+06 - - - 6.4431 0.9998 221125_WJC_METTL3_EV_vs_WT_F01.20899.20899.2 8.70E-05 24-Nov K.IAVPLIQGYTVLR[166.11].L sp|Q8IW92|GLBL2_HUMAN 1 1451.874 1.38 8305 20899 2 1451.875038 726.9443 Beta-galactosidase-1-like protein 2 OS=Homo sapiens OX=9606 GN=GLB1L2 PE=1 SV=1 8.75 3826.2 - 318774 - - - 0.7452 - 2.145 0.448 - 416.5 1 2 0 0.0011 13 0 0 0 2.86E+06 2.07E+06 - - - 4.3082 0.9999 221125_WJC_METTL3_EV_vs_WT_F01.20900.20900.2 8.84E-05 13/26 K.LAYLQILSEETSVK.S "sp|P19525|E2AK2_HUMAN,tr|A0A7P0Z4M0|A0A7P0Z4M0_HUMAN,tr|A0A7P0TBA9|A0A7P0TBA9_HUMAN" 3 1592.8661 0.09 8306 20900 2 1592.865124 797.4403 "Interferon-induced, double-stranded RNA-activated protein kinase OS=Homo sapiens OX=9606 GN=EIF2AK2 PE=1 SV=2" 4.53 3826.3 - 284351 - - - -0.6372 - 2.677 0.424 - 418.7 1 2 0 -0.001 14 0 0 0 1.25E+06 1.38E+07 - - - 4.6434 0.9781 221125_WJC_METTL3_EV_vs_WT_F01.20901.20901.2 0.000125 20-Nov T.SFEQLALPVLR[166.11].N "sp|Q9BSD7|NTPCR_HUMAN,tr|Q5TDF0|Q5TDF0_HUMAN" 2 1281.732 1 8307 20901 2 1281.734932 641.8733 Cancer-related nucleoside-triphosphatase OS=Homo sapiens OX=9606 GN=NTPCR PE=1 SV=1 5.72 3826.4 - 222965 - - - 2.2548 - 2.288 0.457 - 548.9 1 1 0 0.0029 11 0 0 0 3.05E+06 3.06E+06 - - - 4.6546 1 221125_WJC_METTL3_EV_vs_WT_F01.20903.20903.2 8.00E-11 14/30 K.VFLLGEEVAQYDGAYK[136.11].V "sp|P11177|ODPB_HUMAN,tr|F8WF02|F8WF02_HUMAN,tr|C9J634|C9J634_HUMAN" 3 1808.9076 1.32 8309 20903 2 1808.907559 905.4611 "Pyruvate dehydrogenase E1 component subunit beta, mitochondrial OS=Homo sapiens OX=9606 GN=PDHB PE=1 SV=3" 4.14 3826.7 - 128716 - - - -0.0321 - 2.883 0.685 - 495.7 1 2 0 -0.0001 16 0 0 0 2.29E+06 1.74E+06 - - - 6.7036 1 221125_WJC_METTL3_EV_vs_WT_F01.20907.20907.2 6.87E-08 16/28 K.VVLAYEPVWAIGTGK.T "sp|P60174|TPIS_HUMAN,tr|U3KQF3|U3KQF3_HUMAN,tr|U3KPZ0|U3KPZ0_HUMAN" 3 1601.8817 1.35 8312 20907 2 1601.882623 801.9481 Triosephosphate isomerase OS=Homo sapiens OX=9606 GN=TPI1 PE=1 SV=4 5.97 3827.1 - 3.13E+06 - - - 0.5575 - 2.876 0.649 - 801.1 1 2 0 0.0009 15 0 0 0 2.04E+07 1.51E+07 - - - 6.4314 0.9999 221125_WJC_METTL3_EV_vs_WT_F01.20908.20908.2 8.19E-05 18-Sep R.DFILPISDVR[166.11].A "sp|Q6UB35|C1TM_HUMAN,tr|A0A087WVM4|A0A087WVM4_HUMAN,tr|B7ZM99|B7ZM99_HUMAN,tr|Q4VXM0|Q4VXM0_HUMAN,tr|Q4VXM1|Q4VXM1_HUMAN" 5 1183.6476 0.75 8313 20908 2 1183.646645 592.8311 "Monofunctional C1-tetrahydrofolate synthase, mitochondrial OS=Homo sapiens OX=9606 GN=MTHFD1L PE=1 SV=1" 4.21 3827.2 - 1.54E+06 - - - -0.844 - 2.11 0.489 - 353.6 1 2 0 -0.001 10 0 0 0 1.01E+07 1.34E+07 - - - 4.7367 1 221125_WJC_METTL3_EV_vs_WT_F01.20909.20909.3 6.36E-07 17/60 R.TPEQVAEEEYLLQELR.K "sp|Q9NPF5|DMAP1_HUMAN,tr|Q5TG39|Q5TG39_HUMAN,tr|Q5TG40|Q5TG40_HUMAN" 3 1945.9633 1.23 8314 20909 3 1945.963675 649.6617 DNA methyltransferase 1-associated protein 1 OS=Homo sapiens OX=9606 GN=DMAP1 PE=1 SV=1 3.98 3827.4 - 856814 - - - 0.1994 - 3.008 0.562 - 362.9 1 2 0 0.0004 16 0 0 0 7.39E+06 5.99E+06 - - - 7.6314 0.9916 221125_WJC_METTL3_EV_vs_WT_F01.20913.20913.2 1.23E-06 24-Sep T.FIGNSTAIQELFK[136.11].R "sp|P04350|TBB4A_HUMAN,sp|Q9BVA1|TBB2B_HUMAN,sp|P07437|TBB5_HUMAN,sp|Q13509|TBB3_HUMAN,sp|Q13885|TBB2A_HUMAN,sp|P68371|TBB4B_HUMAN,sp|Q9BUF5|TBB6_HUMAN,tr|A0A0B4J269|A0A0B4J269_HUMAN,tr|Q5ST81|Q5ST81_HUMAN,tr|Q5JP53|Q5JP53_HUMAN" 10 1474.7911 0.77 8318 20913 2 1474.792218 738.4028 Tubulin beta-4A chain OS=Homo sapiens OX=9606 GN=TUBB4A PE=1 SV=2 6 3827.9 - 474595 - - - 0.7377 - 1.989 0.552 - 136.2 1 1 0 0.0011 13 0 0 0 1.81E+06 2.36E+06 - - - 4.8826 0.9989 221125_WJC_METTL3_EV_vs_WT_F01.20918.20918.3 0.0176 Sep-60 K.VFLLGEEVAQYDGAYK[136.11].V "sp|P11177|ODPB_HUMAN,tr|F8WF02|F8WF02_HUMAN,tr|C9J634|C9J634_HUMAN" 3 1808.9076 -1 8323 20918 3 1808.906925 603.9765 "Pyruvate dehydrogenase E1 component subunit beta, mitochondrial OS=Homo sapiens OX=9606 GN=PDHB PE=1 SV=3" 4.14 3828.5 - 323338 - - - -0.3826 - 1.849 0.278 - 84.1 1 2 0 -0.0007 16 0 0 0 0.00E+00 0.00E+00 - - - 3.2163 0.9991 221125_WJC_METTL3_EV_vs_WT_F01.20920.20920.2 0.000547 16-Aug R.DIVQFVPFR.E "sp|Q96FN4|CPNE2_HUMAN,sp|O75131|CPNE3_HUMAN,sp|O95741|CPNE6_HUMAN,sp|Q86YQ8|CPNE8_HUMAN,sp|Q8IYJ1|CPNE9_HUMAN,sp|Q9UBL6|CPNE7_HUMAN,sp|Q9HCH3|CPNE5_HUMAN,sp|Q96A23|CPNE4_HUMAN,tr|E7ENV7|E7ENV7_HUMAN" 9 1119.6077 1.03 8325 20920 2 1119.610328 560.8111 Copine-2 OS=Homo sapiens OX=9606 GN=CPNE2 PE=1 SV=3 5.84 3828.8 - 254808 - - - 2.3651 - 1.623 0.416 - 222 1 2 0 0.0026 9 0 0 0 6.84E+06 6.65E+06 - - - 3.5138 0.9998 221125_WJC_METTL3_EV_vs_WT_F01.20921.20921.2 0.0155 16-Oct R.DIVQFVPFR[166.11].E "sp|Q96FN4|CPNE2_HUMAN,sp|O75131|CPNE3_HUMAN,sp|O95741|CPNE6_HUMAN,sp|Q86YQ8|CPNE8_HUMAN,sp|Q8IYJ1|CPNE9_HUMAN,sp|Q9UBL6|CPNE7_HUMAN,sp|Q9HCH3|CPNE5_HUMAN,sp|Q96A23|CPNE4_HUMAN,tr|E7ENV7|E7ENV7_HUMAN" 9 1129.616 1 8326 20921 2 1129.616345 565.8153 Copine-2 OS=Homo sapiens OX=9606 GN=CPNE2 PE=1 SV=3 5.84 3828.9 - 253999 - - - 0.3497 - 1.974 0.421 - 423.9 1 2 0 0.0004 9 0 0 0 6.65E+06 6.65E+06 - - - 4.1178 0.937 221125_WJC_METTL3_EV_vs_WT_F01.20923.20923.2 0.0253 28-Jul R.SYEAVAAAAASVYNY.A sp|Q9BWF3|RBM4_HUMAN 1 1548.7096 - 8328 20923 2 1548.707851 775.3621 RNA-binding protein 4 OS=Homo sapiens OX=9606 GN=RBM4 PE=1 SV=1 4 3829.2 - 224258 - - - -1.1545 - 1.297 0.381 - 104.7 1 1 0 -0.0018 15 0 0 0 - - - - - 2.4939 1 221125_WJC_METTL3_EV_vs_WT_F01.20924.20924.2 8.48E-12 15/30 R.TPEQVAEEEYLLQELR.K "sp|Q9NPF5|DMAP1_HUMAN,tr|Q5TG39|Q5TG39_HUMAN,tr|Q5TG40|Q5TG40_HUMAN" 3 1945.9633 1.54 8329 20924 2 1945.960176 973.9889 DNA methyltransferase 1-associated protein 1 OS=Homo sapiens OX=9606 GN=DMAP1 PE=1 SV=1 3.98 3829.3 - 148172 - - - -1.5987 - 3.638 0.624 - 598.6 1 2 0 -0.0031 16 0 0 0 1.98E+06 1.28E+06 - - - 6.8239 0.9999 221125_WJC_METTL3_EV_vs_WT_F01.20928.20928.2 5.42E-06 22-Sep R.LFPPQWIC[160.03]C[160.03]DIR[166.11].Y sp|Q86U44|MTA70_HUMAN 1 1613.7722 0.02 8331 20928 2 1613.770975 807.8934 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 5.82 3829.7 - 7.31E+07 - - - -0.7653 - 1.866 0.571 - 217.6 1 2 0 -0.0012 12 0 0 0 2.13E+07 9.96E+08 - - - 4.8993 0.9999 221125_WJC_METTL3_EV_vs_WT_F01.20929.20929.2 0.000224 18-Oct R.DFILPISDVR.A "sp|Q6UB35|C1TM_HUMAN,tr|A0A087WVM4|A0A087WVM4_HUMAN,tr|B7ZM99|B7ZM99_HUMAN,tr|Q4VXM0|Q4VXM0_HUMAN,tr|Q4VXM1|Q4VXM1_HUMAN" 5 1173.6394 0.75 8332 20929 2 1173.639579 587.827 "Monofunctional C1-tetrahydrofolate synthase, mitochondrial OS=Homo sapiens OX=9606 GN=MTHFD1L PE=1 SV=1" 4.21 3829.8 - 1.96E+06 - - - 0.1747 - 2.261 0.516 - 449.7 1 2 0 0.0002 10 0 0 0 1.01E+07 1.34E+07 - - - 5.1293 0.9994 221125_WJC_METTL3_EV_vs_WT_F01.20932.20932.2 0.0931 16-Sep R.DLLFQALGR[166.11].T sp|Q9NSD9|SYFB_HUMAN 1 1041.5847 0.99 8335 20932 2 1041.585103 521.7996 Phenylalanine--tRNA ligase beta subunit OS=Homo sapiens OX=9606 GN=FARSB PE=1 SV=3 5.84 3830.1 - 999425 - - - 0.4349 - 1.874 0.28 - 362.4 1 2 0 0.0005 9 0 0 0 8.22E+06 8.33E+06 - - - 2.926 0.9998 221125_WJC_METTL3_EV_vs_WT_F01.20934.20934.2 7.62E-05 20-Dec R.FDEISFVNFAR.G sp|Q08945|SSRP1_HUMAN 1 1343.651 2.81 8337 20934 2 1343.653147 672.8328 FACT complex subunit SSRP1 OS=Homo sapiens OX=9606 GN=SSRP1 PE=1 SV=1 4.37 3830.3 - 913259 - - - 1.5971 - 2.313 0.498 - 633 1 2 0 0.0021 11 0 0 0 1.04E+07 3.70E+06 - - - 4.987 0.9868 221125_WJC_METTL3_EV_vs_WT_F01.20935.20935.2 0.000126 20-Nov R.FDEISFVNFAR[166.11].G sp|Q08945|SSRP1_HUMAN 1 1353.6593 2.81 8338 20935 2 1353.66874 677.8369 FACT complex subunit SSRP1 OS=Homo sapiens OX=9606 GN=SSRP1 PE=1 SV=1 4.37 3830.4 - 785910 - - - 6.9951 - 1.851 0.465 - 332.5 1 2 0 0.0095 11 0 0 0 1.04E+07 3.70E+06 - - - 4.1382 0.9997 221125_WJC_METTL3_EV_vs_WT_F01.20936.20936.2 0.000175 14-Aug R.GFVFITFK[136.11].E "sp|Q99729|ROAA_HUMAN,tr|D6R9P3|D6R9P3_HUMAN,tr|D6RD18|D6RD18_HUMAN,tr|D6RBZ0|D6RBZ0_HUMAN" 4 965.5466 1.24 8339 20936 2 965.546152 483.7806 Heterogeneous nuclear ribonucleoprotein A\B OS=Homo sapiens OX=9606 GN=HNRNPAB PE=1 SV=2 8.75 3830.5 - 691320 - - - -0.4536 - 1.624 0.441 - 281.7 1 2 0 -0.0004 8 0 0 0 1.23E+07 9.92E+06 - - - 3.7605 0.9619 221125_WJC_METTL3_EV_vs_WT_F01.20937.20937.2 0.014 20-Oct T.SFEQLALPVLR.N "sp|Q9BSD7|NTPCR_HUMAN,tr|Q5TDF0|Q5TDF0_HUMAN" 2 1271.7238 1 8340 20937 2 1271.726803 636.8692 Cancer-related nucleoside-triphosphatase OS=Homo sapiens OX=9606 GN=NTPCR PE=1 SV=1 5.72 3830.6 - 505366 - - - 2.3834 - 2.111 0.391 - 433.4 1 1 0 0.003 11 0 0 0 3.05E+06 3.06E+06 - - - 3.9492 0.9999 221125_WJC_METTL3_EV_vs_WT_F01.20938.20938.2 0.000116 13/22 K.TLGVDLVALATR[166.11].V "sp|P27708|PYR1_HUMAN,tr|F8VPD4|F8VPD4_HUMAN" 2 1237.727 3.76 8341 20938 2 1237.725705 619.8708 CAD protein OS=Homo sapiens OX=9606 GN=CAD PE=1 SV=3 5.5 3830.7 - 444966 - - - -1.0115 - 2.334 0.532 - 433.4 1 2 0 -0.0013 12 0 0 0 3.94E+07 1.05E+07 - - - 5.2001 1 221125_WJC_METTL3_EV_vs_WT_F01.20940.20940.2 4.79E-11 13/30 R.TPEQVAEEEYLLQELR[166.11].K "sp|Q9NPF5|DMAP1_HUMAN,tr|Q5TG39|Q5TG39_HUMAN,tr|Q5TG40|Q5TG40_HUMAN" 3 1955.9716 1.54 8343 20940 2 1955.973184 978.9931 DNA methyltransferase 1-associated protein 1 OS=Homo sapiens OX=9606 GN=DMAP1 PE=1 SV=1 3.98 3831 - 337326 - - - 0.8318 - 3.047 0.688 - 468.9 1 2 0 0.0016 16 0 0 0 1.98E+06 1.28E+06 - - - 6.8613 0.8434 221125_WJC_METTL3_EV_vs_WT_F01.20944.20944.2 0.0387 22-Jul K.VVSQYSSLLSPM.S sp|P50991|TCPD_HUMAN 1 1309.6588 - 8346 20944 2 1309.658644 655.8367 T-complex protein 1 subunit delta OS=Homo sapiens OX=9606 GN=CCT4 PE=1 SV=4 5.49 3831.5 - 3.88E+06 - - - -0.1107 - 1.083 0.298 - 92.9 1 1 0 -0.0001 12 0 0 0 - - - - - 1.4518 1 221125_WJC_METTL3_EV_vs_WT_F01.20949.20949.3 2.93E-08 16/60 R.TPEQVAEEEYLLQELR[166.11].K "sp|Q9NPF5|DMAP1_HUMAN,tr|Q5TG39|Q5TG39_HUMAN,tr|Q5TG40|Q5TG40_HUMAN" 3 1955.9716 1.23 8351 20949 3 1955.971343 652.9978 DNA methyltransferase 1-associated protein 1 OS=Homo sapiens OX=9606 GN=DMAP1 PE=1 SV=1 3.98 3832 - 926038 - - - -0.1094 - 2.668 0.534 - 244.9 1 2 0 -0.0002 16 0 0 0 7.39E+06 5.99E+06 - - - 7.0115 1 221125_WJC_METTL3_EV_vs_WT_F01.20956.20956.2 4.69E-08 13/26 K.LLDISELDMVGAGR[166.11].E "sp|Q9H3P2|NELFA_HUMAN,tr|C9JHL4|C9JHL4_HUMAN,tr|C9JEM7|C9JEM7_HUMAN,tr|H0Y3X6|H0Y3X6_HUMAN,tr|H7C2C7|H7C2C7_HUMAN,tr|A0A0C4DFX9|A0A0C4DFX9_HUMAN" 6 1497.7736 0.67 8358 20956 2 1497.778515 749.8941 Negative elongation factor A OS=Homo sapiens OX=9606 GN=NELFA PE=1 SV=3 4.03 3832.9 - 268724 - - - 3.2488 - 2.55 0.628 - 618.7 1 2 0 0.0049 14 0 0 0 1.06E+06 1.59E+06 - - - 6.027 1 221125_WJC_METTL3_EV_vs_WT_F01.20958.20958.2 1.87E-11 13/30 K.MFIGGLSWQTSPDSLR.D "sp|Q96DH6|MSI2H_HUMAN,tr|B4DHE8|B4DHE8_HUMAN,tr|A0A6Q8PF05|A0A6Q8PF05_HUMAN,tr|J3QKT5|J3QKT5_HUMAN,tr|A0A6Q8PFU8|A0A6Q8PFU8_HUMAN,tr|J3KTC1|J3KTC1_HUMAN,tr|A0A6Q8PHT3|A0A6Q8PHT3_HUMAN" 7 1793.8771 1.21 8360 20958 2 1793.877574 897.9458 RNA-binding protein Musashi homolog 2 OS=Homo sapiens OX=9606 GN=MSI2 PE=1 SV=1 5.59 3833.1 - 253701 - - - 0.2893 - 2.788 0.643 - 555.9 1 2 0 0.0005 16 0 0 0 1.14E+06 9.45E+05 - - - 6.3108 0.9919 221125_WJC_METTL3_EV_vs_WT_F01.20961.20961.2 0.00214 14-Oct A.PGFAQMLK[136.11].E sp|P50990|TCPQ_HUMAN 1 898.4826 0.27 8363 20961 2 898.482911 450.2486 T-complex protein 1 subunit theta OS=Homo sapiens OX=9606 GN=CCT8 PE=1 SV=4 9.18 3833.5 - 217964 - - - 0.3361 - 2.179 0.452 - 263.2 1 1 0 0.0003 8 0 0 0 4.59E+05 1.70E+06 - - - 4.7284 0.9938 221125_WJC_METTL3_EV_vs_WT_F01.20963.20963.3 4.90E-05 Sep-36 F.PPQWIC[160.03]C[160.03]DIR[166.11].Y sp|Q86U44|MTA70_HUMAN 1 1353.6197 0.001 8365 20963 3 1353.618997 452.2139 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 6.18 3833.8 - 117569 - - - -0.543 - 1.712 0.503 - 159.8 1 1 0 -0.0007 10 0 0 0 0.00E+00 1.95E+06 - - - 5.718 0.9995 221125_WJC_METTL3_EV_vs_WT_F01.20968.20968.2 0.000124 14-Jul R.GFVFITFK.E "sp|Q99729|ROAA_HUMAN,tr|D6R9P3|D6R9P3_HUMAN,tr|D6RD18|D6RD18_HUMAN,tr|D6RBZ0|D6RBZ0_HUMAN" 4 957.5324 1.15 8368 20968 2 957.533569 479.7735 Heterogeneous nuclear ribonucleoprotein A\B OS=Homo sapiens OX=9606 GN=HNRNPAB PE=1 SV=2 8.75 3834.3 - 2.74E+06 - - - 1.2313 - 1.551 0.406 - 171.2 1 2 0 0.0012 8 0 0 0 1.13E+07 9.82E+06 - - - 3.363 1 221125_WJC_METTL3_EV_vs_WT_F01.20969.20969.2 1.20E-08 13/22 K.ITAEEMYDIFGK.Y sp|Q9Y3B4|SF3B6_HUMAN 1 1415.6643 1.13 8369 20969 2 1415.665776 708.8394 Splicing factor 3B subunit 6 OS=Homo sapiens OX=9606 GN=SF3B6 PE=1 SV=1 4.14 3834.4 - 1.83E+06 - - - 1.0652 - 2.57 0.607 - 607.6 1 2 0 0.0015 12 0 0 0 1.69E+07 1.50E+07 - - - 6.0074 0.9999 221125_WJC_METTL3_EV_vs_WT_F01.20970.20970.2 4.13E-05 18-Dec R.WYEWLDPSIK.K sp|Q99459|CDC5L_HUMAN 1 1335.6499 1.77 8370 20970 2 1335.650505 668.8322 Cell division cycle 5-like protein OS=Homo sapiens OX=9606 GN=CDC5L PE=1 SV=2 4.37 3834.5 - 1.71E+06 - - - 0.4238 - 2.079 0.496 - 493.2 1 2 0 0.0006 10 0 0 0 1.70E+07 9.64E+06 - - - 4.7472 0.9998 221125_WJC_METTL3_EV_vs_WT_F01.20972.20972.2 1.83E-05 20-Dec R.GVTFLFPIQAK.T sp|Q9NR30|DDX21_HUMAN 1 1219.6965 0.83 8372 20972 2 1219.697629 610.8555 Nucleolar RNA helicase 2 OS=Homo sapiens OX=9606 GN=DDX21 PE=1 SV=5 8.75 3834.7 - 1.55E+06 - - - 0.9297 - 2.193 0.409 - 610.7 1 2 0 0.0011 11 0 0 0 4.59E+07 5.50E+07 - - - 4.1859 0.9998 221125_WJC_METTL3_EV_vs_WT_F01.20973.20973.2 0.000321 13/24 R.QVLALELPEALC[160.03]R[166.11].E sp|Q9HBH1|DEFM_HUMAN 1 1520.826 1.16 8373 20973 2 1520.827682 761.4203 "Peptide deformylase, mitochondrial OS=Homo sapiens OX=9606 GN=PDF PE=1 SV=1" 4.53 3834.8 - 1.48E+06 - - - 1.0928 - 2.422 0.49 - 590 1 2 0 0.0017 13 0 0 0 4.25E+06 3.68E+06 - - - 4.93 0.9998 221125_WJC_METTL3_EV_vs_WT_F01.20974.20974.2 0.000224 24-Dec R.QVLALELPEALC[160.03]R.E sp|Q9HBH1|DEFM_HUMAN 1 1510.8177 1.16 8374 20974 2 1510.818843 756.4162 "Peptide deformylase, mitochondrial OS=Homo sapiens OX=9606 GN=PDF PE=1 SV=1" 4.53 3834.9 - 1.33E+06 - - - 0.7234 - 2.46 0.361 - 552.9 1 2 0 0.0011 13 0 0 0 4.25E+06 3.68E+06 - - - 4.0173 1 221125_WJC_METTL3_EV_vs_WT_F01.20975.20975.2 1.53E-06 13/22 K.ITAEEMYDIFGK[136.11].Y sp|Q9Y3B4|SF3B6_HUMAN 1 1423.6785 1.13 8375 20975 2 1423.678753 712.8465 Splicing factor 3B subunit 6 OS=Homo sapiens OX=9606 GN=SF3B6 PE=1 SV=1 4.14 3835 - 1.30E+06 - - - 0.2002 - 2.629 0.619 - 687.2 1 2 0 0.0003 12 0 0 0 1.69E+07 1.50E+07 - - - 6.1561 0.9946 221125_WJC_METTL3_EV_vs_WT_F01.20977.20977.2 0.00196 16-Aug K.ATIEDILFK[136.11].A "sp|Q13888|TF2H2_HUMAN,sp|Q6P1K8|T2H2L_HUMAN,tr|D6RIT7|D6RIT7_HUMAN,tr|D6RGC9|D6RGC9_HUMAN,tr|D6RAW1|D6RAW1_HUMAN,tr|D6RJD3|D6RJD3_HUMAN,tr|D6RID8|D6RID8_HUMAN,tr|R4GMS9|R4GMS9_HUMAN" 8 1056.5947 -1 8377 20977 2 1056.599387 529.3046 General transcription factor IIH subunit 2 OS=Homo sapiens OX=9606 GN=GTF2H2 PE=1 SV=1 4.37 3835.3 - 1.02E+06 - - - 4.4719 - 1.769 0.347 - 192.5 1 2 0 0.0047 9 0 0 0 0.00E+00 0.00E+00 - - - 3.2527 0.9988 221125_WJC_METTL3_EV_vs_WT_F01.20983.20983.2 0.000599 26-Oct K.EILALIPNQNALLK.D sp|Q7L2Z9|CENPQ_HUMAN 1 1548.9239 1.49 8383 20983 2 1548.928581 775.4692 Centromere protein Q OS=Homo sapiens OX=9606 GN=CENPQ PE=1 SV=1 6.1 3836.1 - 512169 - - - 3.0034 - 2.233 0.357 - 238.7 1 2 0 0.0047 14 0 0 0 1.82E+06 1.22E+06 - - - 3.6923 0.9984 221125_WJC_METTL3_EV_vs_WT_F01.20988.20988.2 0.00243 30-Jul K.LFVGGLDWSTTQETLR.S "sp|Q96EP5|DAZP1_HUMAN,tr|K7EK33|K7EK33_HUMAN,tr|K7EQ55|K7EQ55_HUMAN,tr|K7EQ02|K7EQ02_HUMAN" 4 1821.9261 1.34 8387 20988 2 1821.931046 911.9703 DAZ-associated protein 1 OS=Homo sapiens OX=9606 GN=DAZAP1 PE=1 SV=1 4.37 3836.7 - 123663 - - - 2.707 - 1.524 0.423 - 118.9 1 2 0 0.0049 16 0 0 0 1.86E+06 1.39E+06 - - - 3.1996 0.9987 221125_WJC_METTL3_EV_vs_WT_F01.20989.20989.2 3.35E-08 13/26 K.AFYPEEISSMVLTK[136.11].M "sp|P0DMV8|HS71A_HUMAN,sp|P34931|HS71L_HUMAN,sp|P0DMV9|HS71B_HUMAN,tr|Q53FA3|Q53FA3_HUMAN,tr|A0A0G2JIW1|A0A0G2JIW1_HUMAN" 5 1621.8153 0.001 8388 20989 2 1621.807949 811.9149 Heat shock 70 kDa protein 1A OS=Homo sapiens OX=9606 GN=HSPA1A PE=1 SV=1 4.53 3836.7 - 1.42E+07 - - - -4.5301 - 2.082 0.594 - 417.6 1 2 0 -0.0073 14 0 0 0 0.00E+00 1.57E+09 - - - 5.2662 1 221125_WJC_METTL3_EV_vs_WT_F01.20990.20990.3 1.96E-07 13/52 K.AFYPEEISSMVLTK[136.11].M "sp|P0DMV8|HS71A_HUMAN,sp|P34931|HS71L_HUMAN,sp|P0DMV9|HS71B_HUMAN,tr|Q53FA3|Q53FA3_HUMAN,tr|A0A0G2JIW1|A0A0G2JIW1_HUMAN" 5 1621.8153 0.05 8389 20990 3 1621.815126 541.6124 Heat shock 70 kDa protein 1A OS=Homo sapiens OX=9606 GN=HSPA1A PE=1 SV=1 4.53 3836.8 - 6.85E+06 - - - -0.1048 - 2.338 0.555 - 214 1 2 0 -0.0002 14 0 0 0 3.61E+07 6.83E+08 - - - 6.9847 0.9986 221125_WJC_METTL3_EV_vs_WT_F01.20992.20992.2 0.204 20-Aug K.SGAYLIPLLER[166.11].L "sp|P26196|DDX6_HUMAN,tr|Q8IV96|Q8IV96_HUMAN" 2 1240.7055 1.15 8391 20992 2 1240.706286 621.36 Probable ATP-dependent RNA helicase DDX6 OS=Homo sapiens OX=9606 GN=DDX6 PE=1 SV=2 5.72 3836.9 - 3.75E+06 - - - 0.6392 - 1.874 0.195 - 240.5 1 2 0 0.0008 11 0 0 0 6.60E+07 5.75E+07 - - - 2.1801 0.9999 221125_WJC_METTL3_EV_vs_WT_F01.20998.20998.2 5.90E-08 13/26 K.TFAPEEISAMVLTK[136.11].M "sp|P11021|BIP_HUMAN,tr|A0A7P0TB36|A0A7P0TB36_HUMAN,tr|A0A7P0TAI0|A0A7P0TAI0_HUMAN" 3 1543.8047 0.6 8397 20998 2 1543.803404 772.9096 Endoplasmic reticulum chaperone BiP OS=Homo sapiens OX=9606 GN=HSPA5 PE=1 SV=2 4.53 3837.2 - 1.49E+06 - - - -0.8602 - 2.468 0.597 - 516.2 1 2 0 -0.0013 14 0 0 0 2.58E+07 4.32E+07 - - - 5.7171 0.9998 221125_WJC_METTL3_EV_vs_WT_F01.20999.20999.2 0.000694 16-Oct R.YLDVSILGK[136.11].F sp|Q86U44|MTA70_HUMAN 1 1014.5841 0.1 8398 20999 2 1014.584093 508.2993 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 5.83 3837.3 - 1.39E+06 - - - -0.0049 - 1.966 0.418 - 248.6 1 2 0 0 9 0 0 0 4.22E+06 4.36E+07 - - - 4.0841 0.9999 221125_WJC_METTL3_EV_vs_WT_F01.21000.21000.2 2.00E-06 13/26 K.TFAPEEISAMVLTK.M "sp|P11021|BIP_HUMAN,tr|A0A7P0TB36|A0A7P0TB36_HUMAN,tr|A0A7P0TAI0|A0A7P0TAI0_HUMAN" 3 1535.7905 0.6 8399 21000 2 1535.79112 768.9025 Endoplasmic reticulum chaperone BiP OS=Homo sapiens OX=9606 GN=HSPA5 PE=1 SV=2 4.53 3837.5 - 910946 - - - 0.3829 - 2.448 0.495 - 462.4 1 2 0 0.0006 14 0 0 0 2.58E+07 4.32E+07 - - - 4.9435 1 221125_WJC_METTL3_EV_vs_WT_F01.21001.21001.2 2.58E-06 14/30 R.VIFLEDDDVAAVVDGR.L "sp|Q06210|GFPT1_HUMAN,tr|A0A6I8PRN4|A0A6I8PRN4_HUMAN,tr|A0A6I8PTT9|A0A6I8PTT9_HUMAN" 3 1731.8679 1.3 8400 21001 2 1731.866647 866.9412 Glutamine--fructose-6-phosphate aminotransferase [isomerizing] 1 OS=Homo sapiens OX=9606 GN=GFPT1 PE=1 SV=3 3.71 3837.6 - 736692 - - - -0.7408 - 3.069 0.594 - 613.4 1 2 0 -0.0013 16 0 0 0 8.94E+06 6.88E+06 - - - 6.1848 1 221125_WJC_METTL3_EV_vs_WT_F01.21002.21002.2 7.87E-08 13/20 R.DINAVLIDMER.Q "sp|P55265|DSRAD_HUMAN,tr|A0A3B3ITG9|A0A3B3ITG9_HUMAN,tr|A0A3B3IRQ9|A0A3B3IRQ9_HUMAN,tr|A0A3B3ISU1|A0A3B3ISU1_HUMAN,tr|A0A7P0Z4K3|A0A7P0Z4K3_HUMAN,tr|A0A7P0TA14|A0A7P0TA14_HUMAN,tr|A0A3B3ISX1|A0A3B3ISX1_HUMAN,tr|A0A7P0Z4F9|A0A7P0Z4F9_HUMAN" 8 1287.6493 0.81 8401 21002 2 1287.649707 644.8319 Double-stranded RNA-specific adenosine deaminase OS=Homo sapiens OX=9606 GN=ADAR PE=1 SV=4 4.03 3837.7 - 718953 - - - 0.3262 - 2.66 0.631 - 795.1 1 2 0 0.0004 11 0 0 0 7.68E+06 9.52E+06 - - - 6.348 1 221125_WJC_METTL3_EV_vs_WT_F01.21011.21011.3 2.08E-06 Dec-52 K.TFAPEEISAMVLTK[136.11].M "sp|P11021|BIP_HUMAN,tr|A0A7P0TB36|A0A7P0TB36_HUMAN,tr|A0A7P0TAI0|A0A7P0TAI0_HUMAN" 3 1543.8047 0.54 8409 21011 3 1543.803696 515.6089 Endoplasmic reticulum chaperone BiP OS=Homo sapiens OX=9606 GN=HSPA5 PE=1 SV=2 4.53 3838.7 - 2.28E+06 - - - -0.6711 - 2.317 0.49 - 262.1 1 2 0 -0.001 14 0 0 0 9.74E+06 1.80E+07 - - - 6.2358 1 221125_WJC_METTL3_EV_vs_WT_F01.21012.21012.2 5.08E-06 13/20 R.DINAVLIDMER[166.11].Q "sp|P55265|DSRAD_HUMAN,tr|A0A3B3ITG9|A0A3B3ITG9_HUMAN,tr|A0A3B3IRQ9|A0A3B3IRQ9_HUMAN,tr|A0A3B3ISU1|A0A3B3ISU1_HUMAN,tr|A0A7P0Z4K3|A0A7P0Z4K3_HUMAN,tr|A0A7P0TA14|A0A7P0TA14_HUMAN,tr|A0A3B3ISX1|A0A3B3ISX1_HUMAN,tr|A0A7P0Z4F9|A0A7P0Z4F9_HUMAN" 8 1297.6576 0.82 8410 21012 2 1297.656447 649.8361 Double-stranded RNA-specific adenosine deaminase OS=Homo sapiens OX=9606 GN=ADAR PE=1 SV=4 4.03 3838.7 - 2.26E+06 - - - -0.8554 - 2.638 0.573 - 779 1 2 0 -0.0011 11 0 0 0 7.96E+06 9.65E+06 - - - 5.897 1 221125_WJC_METTL3_EV_vs_WT_F01.21014.21014.2 4.01E-12 17/30 R.VIFLEDDDVAAVVDGR[166.11].L "sp|Q06210|GFPT1_HUMAN,tr|A0A6I8PRN4|A0A6I8PRN4_HUMAN,tr|A0A6I8PTT9|A0A6I8PTT9_HUMAN" 3 1741.8762 1.3 8412 21014 2 1741.87452 871.9454 Glutamine--fructose-6-phosphate aminotransferase [isomerizing] 1 OS=Homo sapiens OX=9606 GN=GFPT1 PE=1 SV=3 3.71 3838.9 - 1.72E+06 - - - -0.9645 - 3.504 0.681 - 1006.7 1 2 0 -0.0017 16 0 0 0 8.94E+06 6.88E+06 - - - 7.1531 1 221125_WJC_METTL3_EV_vs_WT_F01.21016.21016.3 3.07E-08 16/60 R.VIFLEDDDVAAVVDGR.L "sp|Q06210|GFPT1_HUMAN,tr|A0A6I8PRN4|A0A6I8PRN4_HUMAN,tr|A0A6I8PTT9|A0A6I8PTT9_HUMAN" 3 1731.8679 1.53 8414 21016 3 1731.868048 578.2966 Glutamine--fructose-6-phosphate aminotransferase [isomerizing] 1 OS=Homo sapiens OX=9606 GN=GFPT1 PE=1 SV=3 3.71 3839.1 - 1.62E+06 - - - 0.0681 - 3.173 0.668 - 268.5 1 2 0 0.0001 16 0 0 0 5.09E+06 3.32E+06 - - - 8.9503 0.9998 221125_WJC_METTL3_EV_vs_WT_F01.21018.21018.2 1.54E-07 24-Dec R.APLPDLYPFGTMR.G "sp|Q92841|DDX17_HUMAN,tr|A0A5H1ZRQ2|A0A5H1ZRQ2_HUMAN,tr|A0A1X7SBZ2|A0A1X7SBZ2_HUMAN" 3 1476.7435 1.09 8416 21018 2 1476.746003 739.379 Probable ATP-dependent RNA helicase DDX17 OS=Homo sapiens OX=9606 GN=DDX17 PE=1 SV=2 5.88 3839.3 - 829619 - - - 1.68 - 2.193 0.57 - 491.5 1 2 0 0.0025 13 0 0 0 1.48E+07 1.35E+07 - - - 5.2657 0.9997 221125_WJC_METTL3_EV_vs_WT_F01.21022.21022.2 0.00319 16-Jul K.AFVPAILFK.D sp|Q9HAU5|RENT2_HUMAN 1 1004.6059 -1 8420 21022 2 1004.605389 503.3102 Regulator of nonsense transcripts 2 OS=Homo sapiens OX=9606 GN=UPF2 PE=1 SV=1 8.8 3839.8 - 573459 - - - -0.4977 - 1.531 0.456 - 166.8 1 2 0 -0.0005 9 0 0 0 0.00E+00 0.00E+00 - - - 3.6411 0.9998 221125_WJC_METTL3_EV_vs_WT_F01.21031.21031.2 0.0217 20-Nov K.SGAYLIPLLER.L "sp|P26196|DDX6_HUMAN,tr|Q8IV96|Q8IV96_HUMAN" 2 1230.6972 1.15 8428 21031 2 1230.69728 616.3559 Probable ATP-dependent RNA helicase DDX6 OS=Homo sapiens OX=9606 GN=DDX6 PE=1 SV=2 5.72 3841 - 1.46E+07 - - - 0.0463 - 2.188 0.379 - 437.9 1 2 0 0.0001 11 0 0 0 6.60E+07 5.74E+07 - - - 3.9584 0.9999 221125_WJC_METTL3_EV_vs_WT_F01.21032.21032.2 1.71E-06 22-Nov R.LEGLTDEINFLR.Q "sp|P05787|K2C8_HUMAN,tr|F8VUG2|F8VUG2_HUMAN,tr|F8VP67|F8VP67_HUMAN,tr|F8W1U3|F8W1U3_HUMAN" 4 1418.7405 1.72 8429 21032 2 1418.740165 710.3775 "Keratin, type II cytoskeletal 8 OS=Homo sapiens OX=9606 GN=KRT8 PE=1 SV=7" 4.14 3841.1 - 6.13E+06 - - - -0.2678 - 2.542 0.528 - 543.4 1 2 0 -0.0004 12 0 0 0 2.12E+07 1.23E+07 - - - 5.3954 1 221125_WJC_METTL3_EV_vs_WT_F01.21033.21033.3 1.24E-06 Nov-52 K.TFAPEEISAMVLTK.M "sp|P11021|BIP_HUMAN,tr|A0A7P0TB36|A0A7P0TB36_HUMAN,tr|A0A7P0TAI0|A0A7P0TAI0_HUMAN" 3 1535.7905 0.54 8430 21033 3 1535.790184 512.9375 Endoplasmic reticulum chaperone BiP OS=Homo sapiens OX=9606 GN=HSPA5 PE=1 SV=2 4.53 3841.1 - 1.84E+06 - - - -0.2266 - 2.081 0.505 - 177.9 1 2 0 -0.0003 14 0 0 0 9.74E+06 1.80E+07 - - - 6.1177 0.9945 221125_WJC_METTL3_EV_vs_WT_F01.21034.21034.2 3.75E-07 13/20 R.DSLIFLVDASK[136.11].A sp|P12956|XRCC6_HUMAN 1 1214.6638 1.16 8431 21034 2 1214.656035 608.3392 X-ray repair cross-complementing protein 6 OS=Homo sapiens OX=9606 GN=XRCC6 PE=1 SV=2 4.21 3841.2 - 1.61E+06 - - - -6.396 - 2.645 0.458 - 452 1 2 0 -0.0078 11 0 0 0 2.68E+07 2.31E+07 - - - 5.0527 0.9999 221125_WJC_METTL3_EV_vs_WT_F01.21035.21035.2 4.41E-05 20-Nov R.DSLIFLVDASK.A sp|P12956|XRCC6_HUMAN 1 1206.6496 1.16 8432 21035 2 1206.648656 604.3321 X-ray repair cross-complementing protein 6 OS=Homo sapiens OX=9606 GN=XRCC6 PE=1 SV=2 4.21 3841.3 - 1.55E+06 - - - -0.7856 - 2.306 0.47 - 325.3 1 2 0 -0.0009 11 0 0 0 2.68E+07 2.31E+07 - - - 4.7724 0.9999 221125_WJC_METTL3_EV_vs_WT_F01.21037.21037.2 1.07E-06 15/26 K.LFIYNPTTGEFLGR[166.11].T "sp|P54709|AT1B3_HUMAN,tr|F8WBY4|F8WBY4_HUMAN,tr|H7C547|H7C547_HUMAN" 3 1636.8489 -1 8434 21037 2 1636.846798 819.4317 Sodium\potassium-transporting ATPase subunit beta-3 OS=Homo sapiens OX=9606 GN=ATP1B3 PE=1 SV=1 6 3841.5 - 1.35E+06 - - - -1.2616 - 2.462 0.543 - 664 1 2 0 -0.0021 14 0 0 0 0.00E+00 0.00E+00 - - - 5.3119 0.9999 221125_WJC_METTL3_EV_vs_WT_F01.21038.21038.2 2.68E-06 13/26 R.VLLATLSIPITPER.T sp|Q14152|EIF3A_HUMAN 1 1521.913 1.3 8435 21038 2 1521.914661 761.9638 Eukaryotic translation initiation factor 3 subunit A OS=Homo sapiens OX=9606 GN=EIF3A PE=1 SV=1 5.97 3841.6 - 1.00E+06 - - - 1.0717 - 2.652 0.501 - 501 1 2 0 0.0016 14 0 0 0 1.96E+07 1.51E+07 - - - 5.1884 0.9999 221125_WJC_METTL3_EV_vs_WT_F01.21039.21039.2 0.000891 13/24 R.APLPDLYPFGTMR[166.11].G "sp|Q92841|DDX17_HUMAN,tr|A0A5H1ZRQ2|A0A5H1ZRQ2_HUMAN,tr|A0A1X7SBZ2|A0A1X7SBZ2_HUMAN" 3 1486.7518 1.1 8436 21039 2 1486.751833 744.3832 Probable ATP-dependent RNA helicase DDX17 OS=Homo sapiens OX=9606 GN=DDX17 PE=1 SV=2 5.88 3841.7 - 963876 - - - 0.0276 - 2.229 0.52 - 558.1 1 2 0 0 13 0 0 0 1.47E+07 1.35E+07 - - - 4.9389 0.9998 221125_WJC_METTL3_EV_vs_WT_F01.21040.21040.2 3.81E-06 26-Nov R.VFGAPEVLENLEVK[136.11].S sp|Q8TEM1|PO210_HUMAN 1 1550.8436 -1 8437 21040 2 1550.843675 776.4291 Nuclear pore membrane glycoprotein 210 OS=Homo sapiens OX=9606 GN=NUP210 PE=1 SV=3 4.25 3841.9 - 898958 - - - 0.0742 - 2.071 0.457 - 297.9 1 2 0 0.0001 14 0 0 0 0.00E+00 0.00E+00 - - - 4.2433 0.9999 221125_WJC_METTL3_EV_vs_WT_F01.21041.21041.3 0.000105 15/60 R.VIFLEDDDVAAVVDGR[166.11].L "sp|Q06210|GFPT1_HUMAN,tr|A0A6I8PRN4|A0A6I8PRN4_HUMAN,tr|A0A6I8PTT9|A0A6I8PTT9_HUMAN" 3 1741.8762 -1 8438 21041 3 1741.876358 581.6327 Glutamine--fructose-6-phosphate aminotransferase [isomerizing] 1 OS=Homo sapiens OX=9606 GN=GFPT1 PE=1 SV=3 3.71 3842 - 878964 - - - 0.0907 - 2.399 0.44 - 316 1 2 0 0.0002 16 0 0 0 0.00E+00 0.00E+00 - - - 5.6908 0.838 221125_WJC_METTL3_EV_vs_WT_F01.21042.21042.2 5.01E-08 22-Nov F.YPEEISSMVLTK[136.11].M "sp|P0DMV8|HS71A_HUMAN,sp|P34931|HS71L_HUMAN,sp|P0DMV9|HS71B_HUMAN,tr|Q53FA3|Q53FA3_HUMAN,tr|A0A0G2JIW1|A0A0G2JIW1_HUMAN" 5 1403.7098 0.05 8439 21042 2 1403.717414 702.8622 Heat shock 70 kDa protein 1A OS=Homo sapiens OX=9606 GN=HSPA1A PE=1 SV=1 4.53 3842.1 - 527876 - - - 5.447 - 2.44 0.474 - 411.5 1 1 0 0.0076 12 0 0 0 4.40E+05 9.31E+06 - - - 4.8866 0.9897 221125_WJC_METTL3_EV_vs_WT_F01.21043.21043.2 0.00468 13/22 K.VPEILQLSDALR[166.11].D "sp|P49589|SYCC_HUMAN,tr|B4DKY1|B4DKY1_HUMAN" 2 1362.7746 13.47 8440 21043 2 1362.783411 682.3946 "Cysteine--tRNA ligase, cytoplasmic OS=Homo sapiens OX=9606 GN=CARS1 PE=1 SV=3" 4.37 3842.2 - 494074 - - - 6.4391 - 2.314 0.382 - 271.8 1 2 0 0.0088 12 0 0 0 3.03E+07 2.25E+06 - - - 4.0672 0.9996 221125_WJC_METTL3_EV_vs_WT_F01.21047.21047.2 2.06E-05 22-Nov K.LTAYAMTIPFVR[166.11].Q "sp|P40939|ECHA_HUMAN,tr|A0A2R8YG21|A0A2R8YG21_HUMAN,tr|A0A2R8Y688|A0A2R8Y688_HUMAN,tr|H0YFD6|H0YFD6_HUMAN,tr|A0A2R8Y4F5|A0A2R8Y4F5_HUMAN" 5 1391.7511 0.67 8444 21047 2 1391.754354 696.8828 "Trifunctional enzyme subunit alpha, mitochondrial OS=Homo sapiens OX=9606 GN=HADHA PE=1 SV=2" 8.75 3842.8 - 385308 - - - 2.3646 - 2.239 0.483 - 572 1 2 0 0.0033 12 0 0 0 4.29E+06 6.42E+06 - - - 4.7282 1 221125_WJC_METTL3_EV_vs_WT_F01.21048.21048.2 7.18E-06 16/28 R.AVFVDLEPTVIDEVR[166.11].T "sp|Q71U36|TBA1A_HUMAN,sp|P68363|TBA1B_HUMAN,sp|Q9BQE3|TBA1C_HUMAN,tr|F8VS66|F8VS66_HUMAN,tr|F8VWV9|F8VWV9_HUMAN,tr|F8VRZ4|F8VRZ4_HUMAN,tr|F8VVB9|F8VVB9_HUMAN,tr|A0A1W2PQM2|A0A1W2PQM2_HUMAN,tr|F5H5D3|F5H5D3_HUMAN,tr|F8VRK0|F8VRK0_HUMAN,tr|F8VQQ4|F8VQQ4_HUMAN,tr|F8VX09|F8VX09_HUMAN" 12 1710.9068 0.6 8445 21048 2 1710.906983 856.4607 Tubulin alpha-1A chain OS=Homo sapiens OX=9606 GN=TUBA1A PE=1 SV=1 3.92 3842.9 - 341116 - - - 0.1233 - 3.342 0.555 - 626.3 1 2 0 0.0002 15 0 0 0 1.01E+08 1.68E+08 - - - 6.1066 0.9879 221125_WJC_METTL3_EV_vs_WT_F01.21051.21051.3 0.0324 Jul-44 R.LEGLTDEINFLR.Q "sp|P05787|K2C8_HUMAN,tr|F8VUG2|F8VUG2_HUMAN,tr|F8VP67|F8VP67_HUMAN,tr|F8W1U3|F8W1U3_HUMAN" 4 1418.7405 -1 8447 21051 3 1418.737722 473.9208 "Keratin, type II cytoskeletal 8 OS=Homo sapiens OX=9606 GN=KRT8 PE=1 SV=7" 4.14 3843.3 - 141765 - - - -1.9898 - 1.676 0.186 - 79.5 1 2 0 -0.0028 12 0 0 0 0.00E+00 0.00E+00 - - - 2.0443 0.9999 221125_WJC_METTL3_EV_vs_WT_F01.21052.21052.3 0.000118 15/56 R.AVFVDLEPTVIDEVR[166.11].T "sp|Q71U36|TBA1A_HUMAN,sp|P68363|TBA1B_HUMAN,sp|Q9BQE3|TBA1C_HUMAN,tr|F8VS66|F8VS66_HUMAN,tr|F8VWV9|F8VWV9_HUMAN,tr|F8VRZ4|F8VRZ4_HUMAN,tr|F8VVB9|F8VVB9_HUMAN,tr|A0A1W2PQM2|A0A1W2PQM2_HUMAN,tr|F5H5D3|F5H5D3_HUMAN,tr|F8VRK0|F8VRK0_HUMAN,tr|F8VQQ4|F8VQQ4_HUMAN,tr|F8VX09|F8VX09_HUMAN" 12 1710.9068 0.57 8448 21052 3 1710.905043 571.3095 Tubulin alpha-1A chain OS=Homo sapiens OX=9606 GN=TUBA1A PE=1 SV=1 3.92 3843.3 - 2.91E+06 - - - -1.0106 - 2.911 0.393 - 373 1 2 0 -0.0017 15 0 0 0 4.38E+07 7.68E+07 - - - 5.7092 1 221125_WJC_METTL3_EV_vs_WT_F01.21053.21053.2 7.08E-10 17/28 R.AVFVDLEPTVIDEVR.T "sp|Q71U36|TBA1A_HUMAN,sp|P68363|TBA1B_HUMAN,sp|Q9BQE3|TBA1C_HUMAN,tr|F8VS66|F8VS66_HUMAN,tr|F8VWV9|F8VWV9_HUMAN,tr|F8VRZ4|F8VRZ4_HUMAN,tr|F8VVB9|F8VVB9_HUMAN,tr|A0A1W2PQM2|A0A1W2PQM2_HUMAN,tr|F5H5D3|F5H5D3_HUMAN,tr|F8VRK0|F8VRK0_HUMAN,tr|F8VQQ4|F8VQQ4_HUMAN,tr|F8VX09|F8VX09_HUMAN" 12 1700.8985 0.6 8449 21053 2 1700.898279 851.4565 Tubulin alpha-1A chain OS=Homo sapiens OX=9606 GN=TUBA1A PE=1 SV=1 3.92 3843.4 - 2.50E+06 - - - -0.1311 - 3.41 0.638 - 776.1 1 2 0 -0.0002 15 0 0 0 1.01E+08 1.68E+08 - - - 6.7691 1 221125_WJC_METTL3_EV_vs_WT_F01.21057.21057.3 4.82E-07 16/56 R.AVFVDLEPTVIDEVR.T "sp|Q71U36|TBA1A_HUMAN,sp|P68363|TBA1B_HUMAN,sp|Q9BQE3|TBA1C_HUMAN,tr|F8VS66|F8VS66_HUMAN,tr|F8VWV9|F8VWV9_HUMAN,tr|F8VRZ4|F8VRZ4_HUMAN,tr|F8VVB9|F8VVB9_HUMAN,tr|A0A1W2PQM2|A0A1W2PQM2_HUMAN,tr|F5H5D3|F5H5D3_HUMAN,tr|F8VRK0|F8VRK0_HUMAN,tr|F8VQQ4|F8VQQ4_HUMAN,tr|F8VX09|F8VX09_HUMAN" 12 1700.8985 0.57 8453 21057 3 1700.897793 567.9734 Tubulin alpha-1A chain OS=Homo sapiens OX=9606 GN=TUBA1A PE=1 SV=1 3.92 3843.6 - 1.74E+06 - - - -0.4168 - 3.032 0.553 - 334.7 1 2 0 -0.0007 15 0 0 0 4.38E+07 7.68E+07 - - - 7.5996 0.9843 221125_WJC_METTL3_EV_vs_WT_F01.21062.21062.2 0.00167 22-Nov S.ILTIDDGIFEVK[136.11].A "sp|P0DMV8|HS71A_HUMAN,sp|P34931|HS71L_HUMAN,sp|P0DMV9|HS71B_HUMAN,tr|Q53FA3|Q53FA3_HUMAN,tr|V9GZ37|V9GZ37_HUMAN,tr|A0A0G2JIW1|A0A0G2JIW1_HUMAN" 6 1369.7584 0.11 8458 21062 2 1369.757898 685.8865 Heat shock 70 kDa protein 1A OS=Homo sapiens OX=9606 GN=HSPA1A PE=1 SV=1 4.03 3844.2 - 695373 - - - -0.3906 - 1.988 0.39 - 280.5 1 1 0 -0.0005 12 0 0 0 7.10E+05 6.56E+06 - - - 3.7293 0.9973 221125_WJC_METTL3_EV_vs_WT_F01.21063.21063.2 0.000154 20-Nov R.SIFTGLMIDPR[166.11].T sp|Q8IWA0|WDR75_HUMAN 1 1258.6619 2.82 8459 21063 2 1258.656269 630.3382 WD repeat-containing protein 75 OS=Homo sapiens OX=9606 GN=WDR75 PE=1 SV=1 5.55 3844.4 - 694897 - - - -4.4849 - 1.82 0.462 - 305 1 2 0 -0.0056 11 0 0 0 1.77E+07 6.27E+06 - - - 4.0716 0.9653 221125_WJC_METTL3_EV_vs_WT_F01.21065.21065.2 0.00925 20-Aug K.SPALAFSLAAT.A "sp|Q96PU8|QKI_HUMAN,tr|F5GYM3|F5GYM3_HUMAN,tr|H0YG47|H0YG47_HUMAN,tr|H0YGD6|H0YGD6_HUMAN" 4 1047.5601 - 8461 21065 2 1047.560031 524.7873 Protein quaking OS=Homo sapiens OX=9606 GN=QKI PE=1 SV=1 5.24 3844.6 - 599584 - - - -0.0286 - 1.752 0.309 - 132.1 1 1 0 0 11 0 0 0 - - - - - 2.8402 0.9988 221125_WJC_METTL3_EV_vs_WT_F01.21066.21066.2 0.000731 13/26 R.IADQFLGAMYTLPR.Q "sp|O60341|KDM1A_HUMAN,tr|R4GMQ1|R4GMQ1_HUMAN,tr|R4GMP9|R4GMP9_HUMAN" 3 1594.8177 4.36 8462 21066 2 1594.82368 798.4162 Lysine-specific histone demethylase 1A OS=Homo sapiens OX=9606 GN=KDM1A PE=1 SV=2 5.84 3844.8 - 596759 - - - 3.7189 - 3.034 0.351 - 520.3 1 2 0 0.0059 14 0 0 0 3.82E+06 8.75E+05 - - - 4.4168 1 221125_WJC_METTL3_EV_vs_WT_F01.21068.21068.2 3.89E-09 30-Oct R.VFVPLPGSTVMLC[160.03]DYK.F sp|Q5SWX8|ODR4_HUMAN 1 1824.9154 3.12 8464 21068 2 1824.91579 913.465 Protein odr-4 homolog OS=Homo sapiens OX=9606 GN=ODR4 PE=1 SV=1 5.8 3845 - 489682 - - - 0.2055 - 2.193 0.705 - 195 1 2 0 0.0004 16 0 0 0 2.16E+06 6.93E+05 - - - 6.1786 0.9609 221125_WJC_METTL3_EV_vs_WT_F01.21073.21073.2 0.00345 14-Jun K.WELLQQMN.V sp|P35908|K22E_HUMAN 1 1060.5012 - 8468 21073 2 1060.501024 531.2579 "Keratin, type II cytoskeletal 2 epidermal OS=Homo sapiens OX=9606 GN=KRT2 PE=1 SV=2" 4 3845.5 - 2.17E+06 - - - -0.1339 - 1.455 0.345 - 166.1 1 1 0 -0.0001 8 0 0 0 - - - - - 2.7201 1 221125_WJC_METTL3_EV_vs_WT_F01.21074.21074.2 5.76E-09 14/28 K.FILPNVSTPVSDAFK.T sp|Q9P2D1|CHD7_HUMAN 1 1633.8716 1.38 8469 21074 2 1633.869349 817.9431 Chromodomain-helicase-DNA-binding protein 7 OS=Homo sapiens OX=9606 GN=CHD7 PE=1 SV=3 5.84 3845.7 - 1.35E+06 - - - -1.3526 - 2.526 0.621 - 534 1 2 0 -0.0022 15 0 0 0 1.15E+07 8.31E+06 - - - 5.9052 0.9998 221125_WJC_METTL3_EV_vs_WT_F01.21075.21075.2 0.00025 22-Sep K.LTAYAMTIPFVR.Q "sp|P40939|ECHA_HUMAN,tr|A0A2R8YG21|A0A2R8YG21_HUMAN,tr|A0A2R8Y688|A0A2R8Y688_HUMAN,tr|H0YFD6|H0YFD6_HUMAN,tr|A0A2R8Y4F5|A0A2R8Y4F5_HUMAN" 5 1381.7428 0.67 8470 21075 2 1381.743299 691.8787 "Trifunctional enzyme subunit alpha, mitochondrial OS=Homo sapiens OX=9606 GN=HADHA PE=1 SV=2" 8.75 3845.8 - 682687 - - - 0.3662 - 1.954 0.481 - 294.8 1 2 0 0.0005 12 0 0 0 4.29E+06 6.42E+06 - - - 4.3561 0.9991 221125_WJC_METTL3_EV_vs_WT_F01.21076.21076.2 3.82E-05 20-Nov R.WPDPEDLLTPR[166.11].W sp|Q8TAE8|G45IP_HUMAN 1 1347.6698 3.56 8471 21076 2 1347.664839 674.8422 Growth arrest and DNA damage-inducible proteins-interacting protein 1 OS=Homo sapiens OX=9606 GN=GADD45GIP1 PE=1 SV=1 4.03 3845.9 - 635649 - - - -3.7079 - 2.257 0.496 - 435.8 1 2 0 -0.005 11 0 0 0 1.25E+07 3.50E+06 - - - 4.905 0.9999 221125_WJC_METTL3_EV_vs_WT_F01.21079.21079.2 5.70E-06 26-Nov R.VLLATLSIPITPER[166.11].T sp|Q14152|EIF3A_HUMAN 1 1531.9213 1.3 8472 21079 2 1531.920865 766.9679 Eukaryotic translation initiation factor 3 subunit A OS=Homo sapiens OX=9606 GN=EIF3A PE=1 SV=1 5.97 3846.3 - 1.97E+06 - - - -0.284 - 2.483 0.454 - 352.6 1 2 0 -0.0004 14 0 0 0 1.96E+07 1.51E+07 - - - 4.6764 0.9991 221125_WJC_METTL3_EV_vs_WT_F01.21080.21080.2 0.000311 14/22 K.LADFALLC[160.03]LDGK.R "sp|P02788|TRFL_HUMAN,tr|E7EQB2|E7EQB2_HUMAN,tr|E7ER44|E7ER44_HUMAN" 3 1334.6904 172.09 8473 21080 2 1334.684782 668.3525 Lactotransferrin OS=Homo sapiens OX=9606 GN=LTF PE=1 SV=6 4.21 3846.4 - 1.64E+06 - - - -4.2272 - 3.084 0.49 - 940.4 1 2 0 -0.0056 12 0 0 0 8.60E+06 5.00E+04 - - - 5.6217 0.9999 221125_WJC_METTL3_EV_vs_WT_F01.21081.21081.2 1.83E-06 22-Oct R.LFPPQWIC[160.03]C[160.03]DIR.Y sp|Q86U44|MTA70_HUMAN 1 1603.7639 0.02 8474 21081 2 1603.762798 802.8892 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 5.82 3846.5 - 1.48E+06 - - - -0.7121 - 1.836 0.561 - 303.8 1 2 0 -0.0011 12 0 0 0 2.20E+07 1.12E+09 - - - 4.7829 0.9997 221125_WJC_METTL3_EV_vs_WT_F01.21083.21083.2 0.000818 20-Dec K.NVPGLAILLSK.D sp|Q9BUL9|RPP25_HUMAN 1 1123.6965 1.03 8476 21083 2 1123.69759 562.8555 Ribonuclease P protein subunit p25 OS=Homo sapiens OX=9606 GN=RPP25 PE=1 SV=1 8.75 3846.8 - 781418 - - - 0.9745 - 1.784 0.456 - 233.1 1 2 0 0.0011 11 0 0 0 4.27E+06 4.13E+06 - - - 3.9746 1 221125_WJC_METTL3_EV_vs_WT_F01.21084.21084.2 9.77E-09 16/28 K.LLDTVDDMLANDIAR.L "sp|Q9H4M9|EHD1_HUMAN,tr|C9J2Z4|C9J2Z4_HUMAN,tr|A0A024R571|A0A024R571_HUMAN" 3 1673.8294 1.77 8477 21084 2 1673.824116 837.922 EH domain-containing protein 1 OS=Homo sapiens OX=9606 GN=EHD1 PE=1 SV=2 3.77 3846.9 - 756240 - - - -3.1783 - 3.334 0.656 - 970.7 1 2 0 -0.0053 15 0 0 0 3.66E+06 2.07E+06 - - - 6.8451 1 221125_WJC_METTL3_EV_vs_WT_F01.21085.21085.2 1.91E-08 13/28 K.LLDTVDDMLANDIAR[166.11].L "sp|Q9H4M9|EHD1_HUMAN,tr|C9J2Z4|C9J2Z4_HUMAN,tr|A0A024R571|A0A024R571_HUMAN" 3 1683.8377 1.77 8478 21085 2 1683.832507 842.9261 EH domain-containing protein 1 OS=Homo sapiens OX=9606 GN=EHD1 PE=1 SV=2 3.77 3847 - 721956 - - - -3.0876 - 2.823 0.593 - 583.1 1 2 0 -0.0052 15 0 0 0 3.66E+06 2.07E+06 - - - 5.9707 0.9996 221125_WJC_METTL3_EV_vs_WT_F01.21086.21086.2 6.05E-07 20-Nov K.DFPLSGYVELR.Y sp|O75489|NDUS3_HUMAN 1 1294.6558 1.17 8479 21086 2 1294.652441 648.3352 "NADH dehydrogenase [ubiquinone] iron-sulfur protein 3, mitochondrial OS=Homo sapiens OX=9606 GN=NDUFS3 PE=1 SV=1" 4.37 3847.2 - 683725 - - - -2.5574 - 2.285 0.474 - 478 1 2 0 -0.0033 11 0 0 0 6.14E+06 5.26E+06 - - - 4.7764 1 221125_WJC_METTL3_EV_vs_WT_F01.21087.21087.2 4.02E-06 14/18 F.PPQWIC[160.03]C[160.03]DIR[166.11].Y sp|Q86U44|MTA70_HUMAN 1 1353.6197 0.001 8480 21087 2 1353.617099 677.8171 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 6.18 3847.3 - 549299 - - - -1.9452 - 2.739 0.584 - 744.2 1 1 0 -0.0026 10 0 0 0 0.00E+00 6.29E+06 - - - 6.1661 0.8097 221125_WJC_METTL3_EV_vs_WT_F01.21088.21088.2 0.0374 14-May T.VADTDDHR.V sp|Q96JM7|LMBL3_HUMAN 1 927.4046 0.98 8481 21088 2 927.405932 464.7096 Lethal(3)malignant brain tumor-like protein 3 OS=Homo sapiens OX=9606 GN=L3MBTL3 PE=1 SV=2 4.41 3847.4 - 351742 - - - 1.4115 - 1.049 0.334 - 71.1 1 1 0 0.0013 8 0 0 0 2.22E+06 2.27E+06 - - - 1.6518 0.981 221125_WJC_METTL3_EV_vs_WT_F01.21093.21093.2 0.00016 22-Jul R.DYLHLPPEIVPA.T "sp|Q9NQ39|RS10L_HUMAN,sp|P46783|RS10_HUMAN,tr|A0A2R8Y6L3|A0A2R8Y6L3_HUMAN,tr|F6U211|F6U211_HUMAN,tr|A0A1W2PQS6|A0A1W2PQS6_HUMAN,tr|A0A2R8YFH6|A0A2R8YFH6_HUMAN,tr|A0A2R8Y7H1|A0A2R8Y7H1_HUMAN,tr|S4R435|S4R435_HUMAN" 8 1362.7184 - 8484 21093 2 1362.718413 682.3665 Putative 40S ribosomal protein S10-like OS=Homo sapiens OX=9606 GN=RPS10P5 PE=5 SV=1 4.35 3848 - 1.57E+06 - - - 0.044 - 1.822 0.389 - 88.4 1 1 0 0.0001 12 0 0 0 - - - - - 3.4927 1 221125_WJC_METTL3_EV_vs_WT_F01.21095.21095.2 6.67E-08 15/24 R.LLSFSPEEFPTLK.A sp|Q5JSZ5|PRC2B_HUMAN 1 1506.797 1.69 8486 21095 2 1506.795449 754.4058 Protein PRRC2B OS=Homo sapiens OX=9606 GN=PRRC2B PE=1 SV=2 4.53 3848.1 - 1.47E+06 - - - -1.0273 - 2.696 0.597 - 751.8 1 2 0 -0.0015 13 0 0 0 4.55E+07 2.69E+07 - - - 5.9954 1 221125_WJC_METTL3_EV_vs_WT_F01.21097.21097.2 2.23E-09 14/24 R.VVSTFGVIFDPVK.Q sp|Q9P2D1|CHD7_HUMAN 1 1406.781 0.68 8488 21097 2 1406.779911 704.3978 Chromodomain-helicase-DNA-binding protein 7 OS=Homo sapiens OX=9606 GN=CHD7 PE=1 SV=3 5.81 3848.4 - 1.10E+06 - - - -0.7407 - 2.665 0.595 - 560 1 2 0 -0.001 13 0 0 0 7.68E+06 1.13E+07 - - - 5.9511 0.998 221125_WJC_METTL3_EV_vs_WT_F01.21098.21098.2 0.00669 18-Jul K.VFFNILEEAR.E "sp|Q9Y276|BCS1_HUMAN,tr|C9J1S9|C9J1S9_HUMAN,tr|C9J8G3|C9J8G3_HUMAN" 3 1236.6503 7.7 8489 21098 2 1236.653314 619.3324 Mitochondrial chaperone BCS1 OS=Homo sapiens OX=9606 GN=BCS1L PE=1 SV=1 4.53 3848.5 - 1.00E+06 - - - 2.4591 - 1.648 0.318 - 100.6 1 2 0 0.003 10 0 0 0 1.20E+07 1.56E+06 - - - 2.7832 1 221125_WJC_METTL3_EV_vs_WT_F01.21099.21099.2 7.23E-09 14/24 R.VVSTFGVIFDPVK[136.11].Q sp|Q9P2D1|CHD7_HUMAN 1 1414.7952 0.7 8490 21099 2 1414.795816 708.4049 Chromodomain-helicase-DNA-binding protein 7 OS=Homo sapiens OX=9606 GN=CHD7 PE=1 SV=3 5.81 3848.6 - 963912 - - - 0.4686 - 2.75 0.662 - 575.8 1 2 0 0.0007 13 0 0 0 8.27E+06 1.18E+07 - - - 6.5266 0.9999 221125_WJC_METTL3_EV_vs_WT_F01.21101.21101.2 3.65E-07 24-Dec R.LLSFSPEEFPTLK[136.11].A sp|Q5JSZ5|PRC2B_HUMAN 1 1514.8112 1.69 8492 21101 2 1514.809754 758.4129 Protein PRRC2B OS=Homo sapiens OX=9606 GN=PRRC2B PE=1 SV=2 4.53 3848.9 - 870559 - - - -0.9526 - 2.283 0.541 - 444.7 1 2 0 -0.0014 13 0 0 0 4.55E+07 2.69E+07 - - - 5.155 0.9909 221125_WJC_METTL3_EV_vs_WT_F01.21106.21106.3 0.351 Aug-52 R.VLLATLSIPITPER[166.11].T sp|Q14152|EIF3A_HUMAN 1 1531.9213 0.03 8497 21106 3 1531.923768 511.6477 Eukaryotic translation initiation factor 3 subunit A OS=Homo sapiens OX=9606 GN=EIF3A PE=1 SV=1 5.97 3849.5 - 344919 - - - 1.611 - 1.561 0.215 - 62.7 1 2 0 0.0025 14 0 0 0 1.08E+05 3.99E+06 - - - 2.1198 1 221125_WJC_METTL3_EV_vs_WT_F01.21114.21114.2 5.82E-06 17/28 K.VSALDLAVLDQVEAR.L "sp|Q13561|DCTN2_HUMAN,tr|H0YHL1|H0YHL1_HUMAN,tr|A8K8J9|A8K8J9_HUMAN,tr|F8W1I6|F8W1I6_HUMAN,tr|A0A7I2V4H4|A0A7I2V4H4_HUMAN,tr|A0A7I2V4Y9|A0A7I2V4Y9_HUMAN" 6 1597.8675 3.23 8503 21114 2 1597.867094 799.941 Dynactin subunit 2 OS=Homo sapiens OX=9606 GN=DCTN2 PE=1 SV=4 4.03 3850.4 - 1.66E+06 - - - -0.2766 - 3.212 0.538 - 1206.4 1 2 0 -0.0004 15 0 0 0 1.10E+07 3.41E+06 - - - 5.8834 0.9999 221125_WJC_METTL3_EV_vs_WT_F01.21115.21115.2 5.96E-07 26-Oct R.ILSVQGTEPLVLFK.E "sp|Q9H8H0|NOL11_HUMAN,tr|J3QLQ6|J3QLQ6_HUMAN" 2 1542.9021 1.22 8504 21115 2 1542.900743 772.4583 Nucleolar protein 11 OS=Homo sapiens OX=9606 GN=NOL11 PE=1 SV=1 6 3850.4 - 2.77E+06 - - - -0.8996 - 2.152 0.536 - 302.9 1 2 0 -0.0014 14 0 0 0 1.15E+07 9.45E+06 - - - 4.9227 1 221125_WJC_METTL3_EV_vs_WT_F01.21116.21116.3 5.48E-07 Nov-44 K.VDALMDEINFMK.M "sp|P13647|K2C5_HUMAN,tr|H0YIN9|H0YIN9_HUMAN" 2 1424.668 999 8505 21116 3 1424.667147 475.8966 "Keratin, type II cytoskeletal 5 OS=Homo sapiens OX=9606 GN=KRT5 PE=1 SV=3" 4.03 3850.5 - 1.63E+06 - - - -0.5805 - 2.199 0.525 - 233.4 1 2 0 -0.0008 12 0 0 0 7.30E+06 0.00E+00 - - - 6.5772 0.9999 221125_WJC_METTL3_EV_vs_WT_F01.21118.21118.2 0.000241 22-Nov R.NFGASLLLPGLK[136.11].Q "sp|Q92552|RT27_HUMAN,tr|G5EA06|G5EA06_HUMAN,tr|D6RH20|D6RH20_HUMAN,tr|D6RJC7|D6RJC7_HUMAN" 4 1236.7322 1.35 8507 21118 2 1236.732398 619.3734 "28S ribosomal protein S27, mitochondrial OS=Homo sapiens OX=9606 GN=MRPS27 PE=1 SV=3" 8.75 3850.7 - 1.48E+06 - - - 0.1933 - 1.935 0.527 - 348.6 1 2 0 0.0002 12 0 0 0 1.34E+07 9.94E+06 - - - 4.6702 0.9999 221125_WJC_METTL3_EV_vs_WT_F01.21120.21120.2 0.000119 13/26 K.TGAAGAEALSLLLK.R "sp|Q9P2N6|KANL3_HUMAN,tr|C9J5A4|C9J5A4_HUMAN,tr|A0A590UJ53|A0A590UJ53_HUMAN" 3 1313.7555 2.13 8509 21120 2 1313.753632 657.885 KAT8 regulatory NSL complex subunit 3 OS=Homo sapiens OX=9606 GN=KANSL3 PE=1 SV=2 5.66 3851 - 1.22E+06 - - - -1.3968 - 2.695 0.542 - 450 1 2 0 -0.0018 14 0 0 0 6.33E+06 2.97E+06 - - - 5.5315 0.9913 221125_WJC_METTL3_EV_vs_WT_F01.21121.21121.2 6.11E-07 30-Nov R.LVEGILHAPDAGWGNL.V "sp|Q13148|TADBP_HUMAN,tr|A0A087WX29|A0A087WX29_HUMAN,tr|K7EJ99|K7EJ99_HUMAN,tr|G3V162|G3V162_HUMAN,tr|A0A0A0MSV7|A0A0A0MSV7_HUMAN,tr|A0A087WYY0|A0A087WYY0_HUMAN,tr|K7EN94|K7EN94_HUMAN,tr|A0A0A0N0M3|A0A0A0N0M3_HUMAN,tr|B1AKP7|B1AKP7_HUMAN,tr|K7EJM5|K7EJM5_HUMAN,tr|A0A087X260|A0A087X260_HUMAN" 11 1660.8573 - 8510 21121 2 1660.855938 831.4359 TAR DNA-binding protein 43 OS=Homo sapiens OX=9606 GN=TARDBP PE=1 SV=1 4.35 3851 - 1.10E+06 - - - -0.8237 - 2.571 0.454 - 230.5 1 1 0 -0.0014 16 0 0 0 - - - - - 4.7154 0.9999 221125_WJC_METTL3_EV_vs_WT_F01.21124.21124.3 2.41E-05 Dec-56 K.VSALDLAVLDQVEAR.L "sp|Q13561|DCTN2_HUMAN,tr|H0YHL1|H0YHL1_HUMAN,tr|A8K8J9|A8K8J9_HUMAN,tr|F8W1I6|F8W1I6_HUMAN,tr|A0A7I2V4H4|A0A7I2V4H4_HUMAN,tr|A0A7I2V4Y9|A0A7I2V4Y9_HUMAN" 6 1597.8675 3.35 8513 21124 3 1597.869982 533.6298 Dynactin subunit 2 OS=Homo sapiens OX=9606 GN=DCTN2 PE=1 SV=4 4.03 3851.3 - 972079 - - - 1.5308 - 2.841 0.437 - 260.6 1 2 0 0.0024 15 0 0 0 4.34E+06 1.29E+06 - - - 6.136 0.9999 221125_WJC_METTL3_EV_vs_WT_F01.21126.21126.2 3.29E-09 14/26 K.TGAAGAEALSLLLK[136.11].R "sp|Q9P2N6|KANL3_HUMAN,tr|C9J5A4|C9J5A4_HUMAN,tr|A0A590UJ53|A0A590UJ53_HUMAN" 3 1321.7697 2.13 8515 21126 2 1321.76858 661.8921 KAT8 regulatory NSL complex subunit 3 OS=Homo sapiens OX=9606 GN=KANSL3 PE=1 SV=2 5.66 3851.5 - 759264 - - - -0.8224 - 2.849 0.509 - 590.4 1 2 0 -0.0011 14 0 0 0 6.33E+06 2.97E+06 - - - 5.4274 0.8201 221125_WJC_METTL3_EV_vs_WT_F01.21127.21127.2 0.559 16-Jul R.DLSAAGIGL.L "sp|P43243|MATR3_HUMAN,tr|A0A1B0GX04|A0A1B0GX04_HUMAN,tr|D6RBS2|D6RBS2_HUMAN,tr|A8MXP9|A8MXP9_HUMAN,tr|D6R991|D6R991_HUMAN,tr|D6REK4|D6REK4_HUMAN,tr|D6R9F3|D6R9F3_HUMAN,tr|A0A0R4J2E8|A0A0R4J2E8_HUMAN,tr|D6RB45|D6RB45_HUMAN,tr|D6RCM3|D6RCM3_HUMAN,tr|D6R8Z5|D6R8Z5_HUMAN,tr|D6REM6|D6REM6_HUMAN" 12 815.4389 - 8516 21127 2 815.437717 408.7267 Matrin-3 OS=Homo sapiens OX=9606 GN=MATR3 PE=1 SV=2 3.8 3851.6 - 755038 - - - -1.4299 - 1.243 0.266 - 130.8 1 1 0 -0.0012 9 0 0 0 - - - - - 1.6346 0.9994 221125_WJC_METTL3_EV_vs_WT_F01.21129.21129.2 0.0045 18-Nov R.GVVLFPWQAR.L sp|Q9Y2S7|PDIP2_HUMAN 1 1171.6502 0.75 8518 21129 2 1171.650883 586.8324 Polymerase delta-interacting protein 2 OS=Homo sapiens OX=9606 GN=POLDIP2 PE=1 SV=1 9.75 3851.9 - 529569 - - - 0.571 - 2.015 0.27 - 506.6 1 2 0 0.0007 10 0 0 0 2.46E+06 3.27E+06 - - - 2.9907 0.9735 221125_WJC_METTL3_EV_vs_WT_F01.21130.21130.2 0.112 26-Jul R.YSVQLLTPANLLAK[136.11].L "sp|Q9Y265|RUVB1_HUMAN,tr|H7C4G5|H7C4G5_HUMAN" 2 1537.8959 0.6 8519 21130 2 1537.890674 769.9552 RuvB-like 1 OS=Homo sapiens OX=9606 GN=RUVBL1 PE=1 SV=1 8.59 3852 - 461580 - - - -3.4177 - 1.252 0.214 - 120.8 1 2 0 -0.0053 14 0 0 0 1.72E+06 2.89E+06 - - - 1.1839 0.989 221125_WJC_METTL3_EV_vs_WT_F01.21136.21136.2 0.000365 28-Dec K.VTIAQGGVLPNIQAV.L "sp|Q9BTM1|H2AJ_HUMAN,sp|Q93077|H2A1C_HUMAN,sp|Q99878|H2A1J_HUMAN,sp|Q16777|H2A2C_HUMAN,sp|P04908|H2A1B_HUMAN,sp|P20671|H2A1D_HUMAN,sp|P0C0S8|H2A1_HUMAN,sp|Q6FI13|H2A2A_HUMAN,sp|Q96KK5|H2A1H_HUMAN,sp|Q7L7L0|H2A3_HUMAN,tr|A0A0U1RR32|A0A0U1RR32_HUMAN,tr|A0A0U1RRH7|A0A0U1RRH7_HUMAN,tr|H0YFX9|H0YFX9_HUMAN" 13 1478.8457 - 8524 21136 2 1478.844386 740.4301 Histone H2A.J OS=Homo sapiens OX=9606 GN=H2AJ PE=1 SV=1 5.49 3852.7 - 1.62E+06 - - - -0.8743 - 2.228 0.456 - 310.8 1 1 0 -0.0013 15 0 0 0 - - - - - 4.3782 0.9999 221125_WJC_METTL3_EV_vs_WT_F01.21141.21141.2 0.00228 20-Dec K.LSDLDYMQFIR.L sp|P82933|RT09_HUMAN 1 1399.6806 0.87 8529 21141 2 1399.681479 700.8476 "28S ribosomal protein S9, mitochondrial OS=Homo sapiens OX=9606 GN=MRPS9 PE=1 SV=2" 4.21 3853.2 - 915486 - - - 0.6373 - 2.786 0.415 - 887.2 1 2 0 0.0009 11 0 0 0 2.79E+06 3.20E+06 - - - 4.8777 0.9992 221125_WJC_METTL3_EV_vs_WT_F01.21142.21142.2 0.000329 22-Nov R.GLFIIDPNGVIK[136.11].H sp|P30048|PRDX3_HUMAN 1 1292.7584 0.64 8530 21142 2 1292.759794 647.3865 "Thioredoxin-dependent peroxide reductase, mitochondrial OS=Homo sapiens OX=9606 GN=PRDX3 PE=1 SV=3" 5.84 3853.4 - 892484 - - - 1.0984 - 2.067 0.263 - 242.2 1 2 0 0.0014 12 0 0 0 1.50E+07 2.35E+07 - - - 2.8936 0.9996 221125_WJC_METTL3_EV_vs_WT_F01.21143.21143.2 0.031 14-Sep M.VLDLDLFR[166.11].V "sp|P49591|SYSC_HUMAN,tr|Q5T5C7|Q5T5C7_HUMAN" 2 999.5629 0.6 8531 21143 2 999.562509 500.7887 "Serine--tRNA ligase, cytoplasmic OS=Homo sapiens OX=9606 GN=SARS1 PE=1 SV=3" 4.21 3853.5 - 839770 - - - -0.3432 - 1.857 0.321 - 339.6 1 2 0 -0.0003 8 0 0 0 3.09E+06 5.16E+06 - - - 3.2786 0.9988 221125_WJC_METTL3_EV_vs_WT_F01.21145.21145.2 0.025 18-Aug K.AIDLMNALMR.L sp|Q96SI9|STRBP_HUMAN 1 1146.5889 0.81 8533 21145 2 1146.587281 574.3017 Spermatid perinuclear RNA-binding protein OS=Homo sapiens OX=9606 GN=STRBP PE=1 SV=1 5.88 3853.8 - 411044 - - - -1.4425 - 1.664 0.281 - 172.3 1 2 0 -0.0017 10 0 0 0 3.45E+06 4.28E+06 - - - 2.5373 0.7975 221125_WJC_METTL3_EV_vs_WT_F01.21147.21147.2 0.0705 16-Jun K.LTPLILK[136.11]PF.G "sp|Q14739|LBR_HUMAN,tr|A0A494C1L1|A0A494C1L1_HUMAN,tr|C9JXK0|C9JXK0_HUMAN" 3 1048.6776 1.15 8535 21147 2 1048.677442 525.3461 Delta(14)-sterol reductase LBR OS=Homo sapiens OX=9606 GN=LBR PE=1 SV=2 8.75 3854 - 317685 - - - -0.1545 - 1.237 0.212 - 103.7 1 1 0 -0.0002 9 0 0 0 3.10E+06 2.69E+06 - - - 1.2221 0.9601 221125_WJC_METTL3_EV_vs_WT_F01.21148.21148.2 3.9 24-Jun K.YFVTFPYPYMNGR.L "sp|Q9P2J5|SYLC_HUMAN,tr|A0A6I8PIV1|A0A6I8PIV1_HUMAN,tr|A0A6I8PLB8|A0A6I8PLB8_HUMAN,tr|A0A6I8PIP7|A0A6I8PIP7_HUMAN,tr|A0A6I8PIT3|A0A6I8PIT3_HUMAN,tr|A0A6I8PTV8|A0A6I8PTV8_HUMAN,tr|A0A6I8PRU9|A0A6I8PRU9_HUMAN,tr|B4DER1|B4DER1_HUMAN,tr|A0A6I8PL42|A0A6I8PL42_HUMAN" 9 1653.765 5.67 8536 21148 2 1653.767756 827.8898 "Leucine--tRNA ligase, cytoplasmic OS=Homo sapiens OX=9606 GN=LARS1 PE=1 SV=2" 8.5 3854.1 - 313836 - - - 1.6756 - 1.027 0.136 - 65.1 1 2 0 0.0028 13 0 0 0 1.80E+06 3.17E+05 - - - 0.113 0.9996 221125_WJC_METTL3_EV_vs_WT_F01.21153.21153.2 4.91E-08 22-Dec K.VMEETLSYLLGR.K "sp|P05089|ARGI1_HUMAN,tr|A0A5F9ZGN6|A0A5F9ZGN6_HUMAN,tr|A0A5F9ZH78|A0A5F9ZH78_HUMAN" 3 1409.7225 -1 8540 21153 2 1409.726557 705.8685 Arginase-1 OS=Homo sapiens OX=9606 GN=ARG1 PE=1 SV=2 4.53 3854.7 - 2.24E+06 - - - 2.9119 - 2.502 0.564 - 529.9 1 2 0 0.0041 12 0 0 0 0.00E+00 0.00E+00 - - - 5.6184 0.9998 221125_WJC_METTL3_EV_vs_WT_F01.21155.21155.2 6.57E-05 20-Dec K.LLTQYILNLGK.Y sp|O00203|AP3B1_HUMAN 1 1274.7598 1.03 8542 21155 2 1274.76092 638.3872 AP-3 complex subunit beta-1 OS=Homo sapiens OX=9606 GN=AP3B1 PE=1 SV=3 8.59 3854.9 - 1.13E+06 - - - 0.8598 - 2.233 0.458 - 492.6 1 2 0 0.0011 11 0 0 0 2.72E+06 2.63E+06 - - - 4.5967 0.9993 221125_WJC_METTL3_EV_vs_WT_F01.21157.21157.2 7.17E-07 24-Oct R.ELPTAFDYVEFTR.S "sp|Q13813|SPTN1_HUMAN,tr|A0A0D9SF54|A0A0D9SF54_HUMAN,tr|A0A0D9SGF6|A0A0D9SGF6_HUMAN" 3 1586.7617 1.49 8544 21157 2 1586.766731 794.3881 "Spectrin alpha chain, non-erythrocytic 1 OS=Homo sapiens OX=9606 GN=SPTAN1 PE=1 SV=3" 4.14 3855.1 - 753145 - - - 3.187 - 2.315 0.473 - 416.5 1 2 0 0.0051 13 0 0 0 4.95E+06 3.32E+06 - - - 4.6874 0.9491 221125_WJC_METTL3_EV_vs_WT_F01.21158.21158.2 0.0054 16-Sep K.LTPLILKPF.G "sp|Q14739|LBR_HUMAN,tr|A0A494C1L1|A0A494C1L1_HUMAN,tr|C9JXK0|C9JXK0_HUMAN" 3 1040.6634 1.14 8545 21158 2 1040.6639 521.339 Delta(14)-sterol reductase LBR OS=Homo sapiens OX=9606 GN=LBR PE=1 SV=2 8.75 3855.2 - 739368 - - - 0.4766 - 1.63 0.283 - 226.3 1 1 0 0.0005 9 0 0 0 3.10E+06 2.71E+06 - - - 2.5446 0.9998 221125_WJC_METTL3_EV_vs_WT_F01.21159.21159.2 0.000162 20-Oct R.LTGLLDLALEK.D sp|P04746|AMYP_HUMAN 1 1184.7016 -1 8546 21159 2 1184.702298 593.3581 Pancreatic alpha-amylase OS=Homo sapiens OX=9606 GN=AMY2A PE=1 SV=2 4.37 3855.3 - 726673 - - - 0.5554 - 2.067 0.457 - 190.1 1 2 0 0.0007 11 0 0 0 0.00E+00 0.00E+00 - - - 4.3805 0.9963 221125_WJC_METTL3_EV_vs_WT_F01.21160.21160.2 1.03E-06 16/26 R.DYGVLLEGSGLALR.G sp|P30048|PRDX3_HUMAN 1 1461.7827 0.93 8547 21160 2 1461.791258 731.8986 "Thioredoxin-dependent peroxide reductase, mitochondrial OS=Homo sapiens OX=9606 GN=PRDX3 PE=1 SV=3" 4.37 3855.5 - 622440 - - - 5.8244 - 2.764 0.477 - 996.3 1 2 0 0.0085 14 0 0 0 4.33E+06 4.65E+06 - - - 5.1128 0.9998 221125_WJC_METTL3_EV_vs_WT_F01.21161.21161.2 8.27E-05 20-Sep K.EYNEFAEVFLK.A sp|O95373|IPO7_HUMAN 1 1387.666 -1 8548 21161 2 1387.666193 694.8403 Importin-7 OS=Homo sapiens OX=9606 GN=IPO7 PE=1 SV=1 4.25 3855.6 - 578298 - - - 0.1513 - 1.906 0.503 - 288.1 1 2 0 0.0002 11 0 0 0 0.00E+00 0.00E+00 - - - 4.501 1 221125_WJC_METTL3_EV_vs_WT_F01.21166.21166.2 1.01E-07 13/26 K.NLPIYSENIIEMYR.G "sp|P35580|MYH10_HUMAN,tr|E7ERA5|E7ERA5_HUMAN" 2 1753.8709 -1 8553 21166 2 1753.871853 877.9427 Myosin-10 OS=Homo sapiens OX=9606 GN=MYH10 PE=1 SV=3 4.53 3856.3 - 182416 - - - 0.5394 - 2.74 0.679 - 517.6 1 2 0 0.0009 14 0 0 0 0.00E+00 0.00E+00 - - - 6.5852 0.9993 221125_WJC_METTL3_EV_vs_WT_F01.21171.21171.2 0.00733 22-Dec R.GLFIIDPNGVIK.H sp|P30048|PRDX3_HUMAN 1 1284.7442 0.64 8557 21171 2 1284.741288 643.3794 "Thioredoxin-dependent peroxide reductase, mitochondrial OS=Homo sapiens OX=9606 GN=PRDX3 PE=1 SV=3" 5.84 3856.9 - 3.26E+06 - - - -2.2464 - 2.179 0.348 - 363.5 1 2 0 -0.0029 12 0 0 0 1.50E+07 2.35E+07 - - - 3.6598 1 221125_WJC_METTL3_EV_vs_WT_F01.21173.21173.3 0.000271 Oct-44 R.LFPPQWIC[160.03]C[160.03]DIR[166.11].Y sp|Q86U44|MTA70_HUMAN 1 1613.7722 0.01 8559 21173 3 1613.772862 538.9313 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 5.82 3857 - 4.97E+06 - - - 0.404 - 1.959 0.5 - 135.1 1 2 0 0.0007 12 0 0 0 1.60E+06 1.08E+08 - - - 5.9782 0.9994 221125_WJC_METTL3_EV_vs_WT_F01.21175.21175.2 7.53E-05 13/26 R.DYGVLLEGSGLALR[166.11].G sp|P30048|PRDX3_HUMAN 1 1471.791 0.93 8561 21175 2 1471.796119 736.9028 "Thioredoxin-dependent peroxide reductase, mitochondrial OS=Homo sapiens OX=9606 GN=PRDX3 PE=1 SV=3" 4.37 3857.2 - 1.35E+06 - - - 3.4686 - 2.587 0.537 - 647.9 1 2 0 0.0051 14 0 0 0 4.03E+06 4.33E+06 - - - 5.3909 0.9812 221125_WJC_METTL3_EV_vs_WT_F01.21177.21177.2 0.00318 20-Oct K.TLSYLLPAIVH.L "sp|P17844|DDX5_HUMAN,tr|A0A7I2V5F5|A0A7I2V5F5_HUMAN,tr|J3QRN5|J3QRN5_HUMAN,tr|A0A7I2V507|A0A7I2V507_HUMAN,tr|J3KTA4|J3KTA4_HUMAN,tr|A0A0G2JLI4|A0A0G2JLI4_HUMAN,tr|A0A7I2V2S0|A0A7I2V2S0_HUMAN,tr|J3QR62|J3QR62_HUMAN,tr|J3QRQ7|J3QRQ7_HUMAN" 9 1225.7071 - 8563 21177 2 1225.708583 613.8608 Probable ATP-dependent RNA helicase DDX5 OS=Homo sapiens OX=9606 GN=DDX5 PE=1 SV=1 6.4 3857.3 - 891667 - - - 1.2425 - 1.861 0.443 - 240.6 1 1 0 0.0015 11 0 0 0 - - - - - 3.9928 1 221125_WJC_METTL3_EV_vs_WT_F01.21178.21178.2 1.53E-08 14/24 R.ELPTAFDYVEFTR[166.11].S "sp|Q13813|SPTN1_HUMAN,tr|A0A0D9SF54|A0A0D9SF54_HUMAN,tr|A0A0D9SGF6|A0A0D9SGF6_HUMAN" 3 1596.7699 1.47 8564 21178 2 1596.770297 799.3922 "Spectrin alpha chain, non-erythrocytic 1 OS=Homo sapiens OX=9606 GN=SPTAN1 PE=1 SV=3" 4.14 3857.5 - 788666 - - - 0.2211 - 2.652 0.632 - 891.7 1 2 0 0.0004 13 0 0 0 4.95E+06 3.36E+06 - - - 6.212 0.9885 221125_WJC_METTL3_EV_vs_WT_F01.21181.21181.2 6.25E-06 20-Aug R.PTPFFMDPIYR.V "sp|Q03112|MECOM_HUMAN,tr|H9KVD4|H9KVD4_HUMAN,tr|E7EUL6|E7EUL6_HUMAN,tr|A0A0C3SFZ7|A0A0C3SFZ7_HUMAN" 4 1382.6693 1.29 8567 21181 2 1382.668431 692.3419 Histone-lysine N-methyltransferase MECOM OS=Homo sapiens OX=9606 GN=MECOM PE=1 SV=3 6.26 3857.8 - 542934 - - - -0.6242 - 1.958 0.453 - 238.3 1 1 0 -0.0009 11 0 0 0 2.27E+06 1.76E+06 - - - 4.2043 0.9996 221125_WJC_METTL3_EV_vs_WT_F01.21183.21183.3 0.0104 13/52 K.LPLFPEPLHVFAPR.A "sp|P26358|DNMT1_HUMAN,tr|A0A7I2V5D0|A0A7I2V5D0_HUMAN,tr|A0A7I2V5F1|A0A7I2V5F1_HUMAN,tr|A0A7I2YQA8|A0A7I2YQA8_HUMAN,tr|A0A7I2YQQ0|A0A7I2YQQ0_HUMAN,tr|K7ENW7|K7ENW7_HUMAN,tr|A0A7I2V490|A0A7I2V490_HUMAN" 7 1631.9188 0.16 8569 21183 3 1631.923121 544.9802 DNA (cytosine-5)-methyltransferase 1 OS=Homo sapiens OX=9606 GN=DNMT1 PE=1 SV=2 6.75 3858.1 - 435078 - - - 2.6576 - 2.529 0.347 - 157 1 2 0 0.0043 14 0 0 0 1.28E+06 8.23E+06 - - - 4.8732 1 221125_WJC_METTL3_EV_vs_WT_F01.21185.21185.3 2.70E-06 14/56 K.LAATNALLNSLEFTK.A "sp|Q14974|IMB1_HUMAN,tr|J3KTM9|J3KTM9_HUMAN" 2 1604.8774 2.02 8571 21185 3 1604.879857 535.9664 Importin subunit beta-1 OS=Homo sapiens OX=9606 GN=KPNB1 PE=1 SV=2 6 3858.3 - 335258 - - - 1.5478 - 2.764 0.483 - 307.2 1 2 0 0.0025 15 0 0 0 4.95E+06 2.46E+06 - - - 6.5772 1 221125_WJC_METTL3_EV_vs_WT_F01.21186.21186.2 2.13E-08 16/30 R.LFVGNLPADITEDEFK[136.11].R sp|P23246|SFPQ_HUMAN 1 1814.9182 0.82 8572 21186 2 1814.917119 908.4664 "Splicing factor, proline- and glutamine-rich OS=Homo sapiens OX=9606 GN=SFPQ PE=1 SV=2" 3.92 3858.5 - 275761 - - - -0.5852 - 3.424 0.653 - 641.9 1 2 0 -0.0011 16 0 0 0 3.98E+06 4.85E+06 - - - 6.8897 1 221125_WJC_METTL3_EV_vs_WT_F01.21194.21194.2 4.48E-08 13/26 R.NFTTEQVTAMLLSK[136.11].L "sp|P34932|HSP74_HUMAN,tr|A0A087WTS8|A0A087WTS8_HUMAN,tr|A0A087WYC1|A0A087WYC1_HUMAN" 3 1589.8214 0.08 8579 21194 2 1589.824403 795.918 Heat shock 70 kDa protein 4 OS=Homo sapiens OX=9606 GN=HSPA4 PE=1 SV=4 6 3859.4 - 1.81E+06 - - - 1.8612 - 2.81 0.651 - 480.8 1 2 0 0.003 14 0 0 0 9.15E+05 1.21E+07 - - - 6.4411 0.9999 221125_WJC_METTL3_EV_vs_WT_F01.21195.21195.3 1.06E-05 13/52 R.NFTTEQVTAMLLSK[136.11].L "sp|P34932|HSP74_HUMAN,tr|A0A087WTS8|A0A087WTS8_HUMAN,tr|A0A087WYC1|A0A087WYC1_HUMAN" 3 1589.8214 0.45 8580 21195 3 1589.824509 530.9478 Heat shock 70 kDa protein 4 OS=Homo sapiens OX=9606 GN=HSPA4 PE=1 SV=4 6 3859.5 - 1.14E+06 - - - 1.9279 - 2.47 0.475 - 299.4 1 2 0 0.0031 14 0 0 0 2.66E+06 5.87E+06 - - - 6.2379 1 221125_WJC_METTL3_EV_vs_WT_F01.21197.21197.2 9.27E-10 16/30 R.LFVGNLPADITEDEFK.R sp|P23246|SFPQ_HUMAN 1 1806.904 0.82 8582 21197 2 1806.904982 904.4593 "Splicing factor, proline- and glutamine-rich OS=Homo sapiens OX=9606 GN=SFPQ PE=1 SV=2" 3.92 3859.7 - 763179 - - - 0.554 - 3.459 0.658 - 512.4 1 2 0 0.001 16 0 0 0 3.98E+06 4.85E+06 - - - 6.9517 0.9999 221125_WJC_METTL3_EV_vs_WT_F01.21200.21200.2 0.000118 15/24 K.NVLIVEDIIDTGK[136.11].T sp|P00492|HPRT_HUMAN 1 1435.8014 0.72 8585 21200 2 1435.802117 718.908 Hypoxanthine-guanine phosphoribosyltransferase OS=Homo sapiens OX=9606 GN=HPRT1 PE=1 SV=2 4.03 3860.1 - 683507 - - - 0.5265 - 2.915 0.49 - 737.2 1 2 0 0.0008 13 0 0 0 2.70E+06 3.72E+06 - - - 5.4058 1 221125_WJC_METTL3_EV_vs_WT_F01.21205.21205.2 9.27E-06 14/24 K.NVLIVEDIIDTGK.T sp|P00492|HPRT_HUMAN 1 1427.7872 0.78 8590 21205 2 1427.787997 714.9009 Hypoxanthine-guanine phosphoribosyltransferase OS=Homo sapiens OX=9606 GN=HPRT1 PE=1 SV=2 4.03 3860.7 - 478975 - - - 0.5855 - 2.843 0.57 - 611.6 1 2 0 0.0008 13 0 0 0 2.91E+06 3.72E+06 - - - 5.9324 0.9999 221125_WJC_METTL3_EV_vs_WT_F01.21206.21206.2 7.29E-06 18-Dec K.DAITQALFLR.E sp|Q9UNX4|WDR3_HUMAN 1 1146.6397 1.01 8591 21206 2 1146.640451 574.3271 WD repeat-containing protein 3 OS=Homo sapiens OX=9606 GN=WDR3 PE=1 SV=1 5.84 3860.8 - 403057 - - - 0.648 - 2.509 0.53 - 415.6 1 2 0 0.0007 10 0 0 0 9.49E+06 9.41E+06 - - - 5.523 0.9993 221125_WJC_METTL3_EV_vs_WT_F01.21208.21208.2 0.00149 20-Sep K.VLAISDLVIYR[166.11].T "sp|Q9HBF4|ZFYV1_HUMAN,tr|G3V5N8|G3V5N8_HUMAN" 2 1270.7524 -1 8593 21208 2 1270.753718 636.3835 Zinc finger FYVE domain-containing protein 1 OS=Homo sapiens OX=9606 GN=ZFYVE1 PE=1 SV=1 5.81 3861.1 - 337574 - - - 1.0026 - 1.815 0.317 - 369.5 1 2 0 0.0013 11 0 0 0 0.00E+00 0.00E+00 - - - 2.9945 0.9997 221125_WJC_METTL3_EV_vs_WT_F01.21209.21209.2 0.125 28-Nov R.QILLYSATFPLSVQK.F sp|P26196|DDX6_HUMAN 1 1706.9607 1.17 8594 21209 2 1706.961693 854.4876 Probable ATP-dependent RNA helicase DDX6 OS=Homo sapiens OX=9606 GN=DDX6 PE=1 SV=2 8.59 3861.2 - 334202 - - - 0.577 - 2.589 0.329 - 318.7 1 2 0 0.001 15 0 0 0 3.25E+06 2.78E+06 - - - 3.8094 0.9998 221125_WJC_METTL3_EV_vs_WT_F01.21210.21210.2 0.00139 14/28 R.QILLYSATFPLSVQK[136.11].F sp|P26196|DDX6_HUMAN 1 1714.9749 1.17 8595 21210 2 1714.976858 858.4947 Probable ATP-dependent RNA helicase DDX6 OS=Homo sapiens OX=9606 GN=DDX6 PE=1 SV=2 8.59 3861.4 - 250421 - - - 1.137 - 2.835 0.443 - 582.8 1 2 0 0.0019 15 0 0 0 3.25E+06 2.78E+06 - - - 4.8743 0.9998 221125_WJC_METTL3_EV_vs_WT_F01.21213.21213.2 5.51E-06 22-Sep R.LFPPQWIC[160.03]C[160.03]DIR[166.11].Y sp|Q86U44|MTA70_HUMAN 1 1613.7722 0.02 8597 21213 2 1613.773248 807.8934 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 5.82 3861.7 - 1.99E+07 - - - 0.6432 - 1.863 0.513 - 221 1 2 0 0.001 12 0 0 0 2.20E+07 1.12E+09 - - - 4.4668 0.9403 221125_WJC_METTL3_EV_vs_WT_F01.21214.21214.2 0.0475 18-Aug K.TNLIVNYLPQ.N "sp|Q12926|ELAV2_HUMAN,sp|P26378|ELAV4_HUMAN,sp|Q15717|ELAV1_HUMAN,sp|Q14576|ELAV3_HUMAN,tr|A0A494C0Q5|A0A494C0Q5_HUMAN,tr|A0A494C0M6|A0A494C0M6_HUMAN,tr|B1AM48|B1AM48_HUMAN,tr|A0A494C0F8|A0A494C0F8_HUMAN,tr|M0QZR9|M0QZR9_HUMAN,tr|A0A494C147|A0A494C147_HUMAN,tr|A0A494C015|A0A494C015_HUMAN,tr|A0A494BZW4|A0A494BZW4_HUMAN,tr|A0A494C1D9|A0A494C1D9_HUMAN,tr|K7EPB5|K7EPB5_HUMAN,tr|A0A0R4J2E6|A0A0R4J2E6_HUMAN,tr|A0A0A0MRX1|A0A0A0MRX1_HUMAN,tr|A0A494C011|A0A494C011_HUMAN,tr|B1APY9|B1APY9_HUMAN" 18 1173.6394 - 8598 21214 2 1173.641842 587.827 ELAV-like protein 2 OS=Homo sapiens OX=9606 GN=ELAVL2 PE=1 SV=2 5.18 3861.8 - 1.20E+06 - - - 2.1029 - 1.643 0.374 - 191.3 1 1 0 0.0025 10 0 0 0 - - - - - 3.1885 0.9995 221125_WJC_METTL3_EV_vs_WT_F01.21217.21217.2 0.00105 18-Nov K.LLEPVLLLGK.E "sp|P62249|RS16_HUMAN,tr|M0R210|M0R210_HUMAN,tr|M0R3H0|M0R3H0_HUMAN,tr|M0QX76|M0QX76_HUMAN,tr|M0R1M5|M0R1M5_HUMAN,tr|Q6IPX4|Q6IPX4_HUMAN" 6 1093.7111 0.86 8601 21217 2 1093.713321 547.8628 40S ribosomal protein S16 OS=Homo sapiens OX=9606 GN=RPS16 PE=1 SV=2 6 3862 - 2.39E+06 - - - 2.0462 - 2.222 0.358 - 355.4 1 2 0 0.0022 10 0 0 0 1.14E+08 1.32E+08 - - - 3.9131 0.9996 221125_WJC_METTL3_EV_vs_WT_F01.21218.21218.2 0.000824 18-Sep K.DAITQALFLR[166.11].E sp|Q9UNX4|WDR3_HUMAN 1 1156.648 1.01 8602 21218 2 1156.650763 579.3313 WD repeat-containing protein 3 OS=Homo sapiens OX=9606 GN=WDR3 PE=1 SV=1 5.84 3862.1 - 1.89E+06 - - - 2.4078 - 2.442 0.454 - 247.6 1 2 0 0.0028 10 0 0 0 9.49E+06 9.41E+06 - - - 4.8855 0.9998 221125_WJC_METTL3_EV_vs_WT_F01.21219.21219.2 2.55E-05 13/26 K.LYTLVTYVPVTTFK.N "sp|P62899|RL31_HUMAN,tr|B7Z4C8|B7Z4C8_HUMAN,tr|B7Z4E3|B7Z4E3_HUMAN,tr|H7C2W9|H7C2W9_HUMAN,tr|C9JU56|C9JU56_HUMAN" 5 1643.9174 1.18 8603 21219 2 1643.920142 822.966 60S ribosomal protein L31 OS=Homo sapiens OX=9606 GN=RPL31 PE=1 SV=1 8.5 3862.1 - 1.67E+06 - - - 1.6394 - 2.513 0.567 - 565.1 1 2 0 0.0027 14 0 0 0 2.54E+07 2.17E+07 - - - 5.5404 1 221125_WJC_METTL3_EV_vs_WT_F01.21220.21220.2 2.88E-07 15/26 K.LYTLVTYVPVTTFK[136.11].N "sp|P62899|RL31_HUMAN,tr|B7Z4C8|B7Z4C8_HUMAN,tr|B7Z4E3|B7Z4E3_HUMAN,tr|H7C2W9|H7C2W9_HUMAN,tr|C9JU56|C9JU56_HUMAN" 5 1651.9316 1.18 8604 21220 2 1651.933745 826.9731 60S ribosomal protein L31 OS=Homo sapiens OX=9606 GN=RPL31 PE=1 SV=1 8.5 3862.2 - 1.58E+06 - - - 1.27 - 2.846 0.634 - 766.8 1 2 0 0.0021 14 0 0 0 2.54E+07 2.17E+07 - - - 6.3477 0.9987 221125_WJC_METTL3_EV_vs_WT_F01.21221.21221.2 0.000269 14-Sep K.NFAFLEFR[166.11].S "sp|P26368|U2AF2_HUMAN,tr|K7ENG2|K7ENG2_HUMAN" 2 1052.5319 0.73 8605 21221 2 1052.535429 527.2732 Splicing factor U2AF 65 kDa subunit OS=Homo sapiens OX=9606 GN=U2AF2 PE=1 SV=4 6 3862.4 - 976977 - - - 3.3662 - 1.707 0.449 - 343.4 1 2 0 0.0035 8 0 0 0 8.85E+06 1.21E+07 - - - 3.9689 1 221125_WJC_METTL3_EV_vs_WT_F01.21222.21222.2 1.35E-06 13/24 K.NPLPVTLTNVVFR.L "sp|P22735|TGM1_HUMAN,tr|H0YMQ8|H0YMQ8_HUMAN" 2 1468.8402 0.64 8606 21222 2 1468.841551 735.4274 Protein-glutamine gamma-glutamyltransferase K OS=Homo sapiens OX=9606 GN=TGM1 PE=1 SV=4 9.75 3862.5 - 931074 - - - 0.9205 - 2.664 0.574 - 410.5 1 2 0 0.0014 13 0 0 0 3.78E+06 5.89E+06 - - - 5.7949 0.9998 221125_WJC_METTL3_EV_vs_WT_F01.21225.21225.2 0.000288 18-Aug K.YVEVFFPQFK.L sp|O75635|SPB7_HUMAN 1 1302.6649 6.27 8609 21225 2 1302.666086 652.3397 Serpin B7 OS=Homo sapiens OX=9606 GN=SERPINB7 PE=1 SV=1 6 3862.8 - 671600 - - - 0.9404 - 1.77 0.474 - 200.5 1 2 0 0.0012 10 0 0 0 4.31E+06 6.88E+05 - - - 4.1354 0.9995 221125_WJC_METTL3_EV_vs_WT_F01.21226.21226.2 2.56E-05 20-Nov K.TLC[160.03]PLC[160.03]FSILK.G "sp|Q9H2P0|ADNP_HUMAN,tr|A0A2R8Y6X0|A0A2R8Y6X0_HUMAN,tr|A0A669KBJ7|A0A669KBJ7_HUMAN" 3 1350.704 1.27 8610 21226 2 1350.70738 676.3593 Activity-dependent neuroprotector homeobox protein OS=Homo sapiens OX=9606 GN=ADNP PE=1 SV=1 7.74 3862.9 - 526998 - - - 2.5276 - 2.135 0.464 - 326 1 2 0 0.0034 11 0 0 0 1.75E+06 1.38E+06 - - - 4.5189 1 221125_WJC_METTL3_EV_vs_WT_F01.21229.21229.3 1.05E-05 13/52 K.VWDLAQQVVLSSYR[166.11].A "sp|Q9BQA1|MEP50_HUMAN,tr|H0Y711|H0Y711_HUMAN" 2 1672.8812 4.46 8613 21229 3 1672.881948 558.6344 Methylosome protein 50 OS=Homo sapiens OX=9606 GN=WDR77 PE=1 SV=1 5.81 3863.3 - 401584 - - - 0.4316 - 2.896 0.46 - 269 1 2 0 0.0007 14 0 0 0 2.89E+07 6.47E+06 - - - 6.4942 0.9968 221125_WJC_METTL3_EV_vs_WT_F01.21232.21232.2 0.0649 14-Jun R.DLVSLFAR[166.11].F sp|Q96IZ5|RBM41_HUMAN 1 929.521 1.39 8616 21232 2 929.52291 465.7678 RNA-binding protein 41 OS=Homo sapiens OX=9606 GN=RBM41 PE=1 SV=2 5.84 3863.7 - 340436 - - - 2.0688 - 1.329 0.303 - 121.7 1 2 0 0.0019 8 0 0 0 1.66E+06 1.20E+06 - - - 2.1362 0.9997 221125_WJC_METTL3_EV_vs_WT_F01.21236.21236.2 0.00636 18-Dec K.LLEPVLLLGK[136.11].E "sp|P62249|RS16_HUMAN,tr|M0R210|M0R210_HUMAN,tr|M0R3H0|M0R3H0_HUMAN,tr|M0QX76|M0QX76_HUMAN,tr|M0R1M5|M0R1M5_HUMAN,tr|Q6IPX4|Q6IPX4_HUMAN" 6 1101.7253 0.86 8619 21236 2 1101.72669 551.8699 40S ribosomal protein S16 OS=Homo sapiens OX=9606 GN=RPS16 PE=1 SV=2 6 3864.1 - 6.99E+06 - - - 1.2771 - 2.445 0.32 - 420.5 1 2 0 0.0014 10 0 0 0 1.13E+08 1.32E+08 - - - 3.8996 0.9999 221125_WJC_METTL3_EV_vs_WT_F01.21237.21237.2 6.83E-05 18-Oct R.TLGWEALLAR.R sp|Q16512|PKN1_HUMAN 1 1128.6291 1.73 8620 21237 2 1128.629103 565.3218 Serine\threonine-protein kinase N1 OS=Homo sapiens OX=9606 GN=PKN1 PE=1 SV=2 5.66 3864.2 - 852971 - - - -0.0363 - 2.087 0.478 - 262.2 1 2 0 0 10 0 0 0 7.13E+06 4.12E+06 - - - 4.6251 0.9998 221125_WJC_METTL3_EV_vs_WT_F01.21238.21238.2 3.25E-05 26-Nov R.YLGGSMDLSTFDFR.T sp|O95983|MBD3_HUMAN 1 1607.729 999 8621 21238 2 1607.731085 804.8718 Methyl-CpG-binding domain protein 3 OS=Homo sapiens OX=9606 GN=MBD3 PE=1 SV=1 4.21 3864.3 - 844423 - - - 1.3006 - 2.209 0.545 - 284.9 1 2 0 0.0021 14 0 0 0 3.77E+06 0.00E+00 - - - 5.0546 0.9972 221125_WJC_METTL3_EV_vs_WT_F01.21240.21240.2 0.257 14-Aug K.SFDLLILK[136.11].E "sp|Q8NI27|THOC2_HUMAN,tr|A0A0C4DG98|A0A0C4DG98_HUMAN" 2 955.5834 0.65 8623 21240 2 955.586025 478.799 THO complex subunit 2 OS=Homo sapiens OX=9606 GN=THOC2 PE=1 SV=2 5.55 3864.5 - 285663 - - - 2.7795 - 1.321 0.377 - 186.4 1 2 0 0.0027 8 0 0 0 8.28E+05 1.28E+06 - - - 2.6643 0.9998 221125_WJC_METTL3_EV_vs_WT_F01.21245.21245.2 7.41E-07 26-Dec R.NFTTEQVTAMLLSK.L "sp|P34932|HSP74_HUMAN,tr|A0A087WTS8|A0A087WTS8_HUMAN,tr|A0A087WYC1|A0A087WYC1_HUMAN" 3 1581.8072 0.08 8628 21245 2 1581.810159 791.9109 Heat shock 70 kDa protein 4 OS=Homo sapiens OX=9606 GN=HSPA4 PE=1 SV=4 6 3865.2 - 142435 - - - 1.8428 - 2.173 0.542 - 214.6 1 2 0 0.0029 14 0 0 0 9.15E+05 1.21E+07 - - - 4.9909 0.9895 221125_WJC_METTL3_EV_vs_WT_F01.21249.21249.2 0.0383 26-Jul K.LSDGIGVMLPQVLK[136.11].G "sp|P52701|MSH6_HUMAN,tr|A0A494C0M1|A0A494C0M1_HUMAN,tr|A0A087WWJ1|A0A087WWJ1_HUMAN" 3 1476.8465 0.47 8632 21249 2 1476.848418 739.4305 DNA mismatch repair protein Msh6 OS=Homo sapiens OX=9606 GN=MSH6 PE=1 SV=2 5.84 3865.7 - 88432.5 - - - 1.2737 - 1.249 0.19 - 59.4 2 2 0 0.0019 14 0 0 0 3.16E+06 6.71E+06 - - - 0.8672 0.8512 221125_WJC_METTL3_EV_vs_WT_F01.21253.21253.2 0.149 18-Jul R.LISQIVSSIT.A "sp|Q9NY65|TBA8_HUMAN,sp|Q9H853|TBA4B_HUMAN,sp|P68366|TBA4A_HUMAN,sp|P68363|TBA1B_HUMAN,sp|Q9BQE3|TBA1C_HUMAN,tr|F8VVB9|F8VVB9_HUMAN,tr|C9JDS9|C9JDS9_HUMAN,tr|A0A7P0TA31|A0A7P0TA31_HUMAN,tr|F5H5D3|F5H5D3_HUMAN,tr|C9J2C0|C9J2C0_HUMAN,tr|A0A7P0T945|A0A7P0T945_HUMAN" 11 1059.6176 - 8634 21253 2 1059.618366 530.8161 Tubulin alpha-8 chain OS=Homo sapiens OX=9606 GN=TUBA8 PE=1 SV=1 5.52 3866.3 - 1.74E+06 - - - 0.7456 - 1.403 0.223 - 114.4 1 1 0 0.0008 10 0 0 0 - - - - - 1.633 0.9994 221125_WJC_METTL3_EV_vs_WT_F01.21254.21254.2 0.00482 14-Sep K.NFAFLEFR.S "sp|P26368|U2AF2_HUMAN,tr|K7ENG2|K7ENG2_HUMAN" 2 1042.5236 0.73 8635 21254 2 1042.523468 522.2691 Splicing factor U2AF 65 kDa subunit OS=Homo sapiens OX=9606 GN=U2AF2 PE=1 SV=4 6 3866.3 - 2.35E+06 - - - -0.142 - 1.648 0.313 - 426.5 1 2 0 -0.0001 8 0 0 0 8.81E+06 1.21E+07 - - - 2.8594 1 221125_WJC_METTL3_EV_vs_WT_F01.21255.21255.2 1.53E-07 24-Dec K.YVFLDPLAGAVTK[136.11].T "sp|Q9NQA3|WASH6_HUMAN,sp|A8K0Z3|WASH1_HUMAN,sp|A8MWX3|WASH4_HUMAN,sp|C4AMC7|WASH3_HUMAN,sp|Q6VEQ5|WASH2_HUMAN,tr|A0A7I2YQU6|A0A7I2YQU6_HUMAN" 6 1400.7795 1.35 8636 21255 2 1400.781146 701.397 WAS protein family homolog 6 OS=Homo sapiens OX=9606 GN=WASH6P PE=1 SV=3 5.83 3866.4 - 1.93E+06 - - - 1.1729 - 2.52 0.629 - 350.6 1 2 0 0.0016 13 0 0 0 1.53E+07 1.13E+07 - - - 6.0584 0.9998 221125_WJC_METTL3_EV_vs_WT_F01.21257.21257.2 0.000132 14/24 R.VLGATLLPDLIQK.V "sp|P55786|PSA_HUMAN,tr|A0A7I2V3W8|A0A7I2V3W8_HUMAN,tr|A0A7I2V389|A0A7I2V389_HUMAN,tr|E9PLK3|E9PLK3_HUMAN,tr|H0YDG0|H0YDG0_HUMAN" 5 1379.8388 0.98 8638 21257 2 1379.841493 690.9267 Puromycin-sensitive aminopeptidase OS=Homo sapiens OX=9606 GN=NPEPPS PE=1 SV=2 5.81 3866.7 - 425840 - - - 1.9502 - 2.514 0.532 - 623.3 1 2 0 0.0027 13 0 0 0 4.37E+06 4.48E+06 - - - 5.3355 0.9999 221125_WJC_METTL3_EV_vs_WT_F01.21261.21261.2 0.000115 18-Sep K.C[160.03]MQLTDFILK[136.11].F "sp|P50914|RL14_HUMAN,tr|E7EPB3|E7EPB3_HUMAN" 2 1275.6447 0.66 8642 21261 2 1275.644964 638.8296 60S ribosomal protein L14 OS=Homo sapiens OX=9606 GN=RPL14 PE=1 SV=4 5.83 3867.2 - 238092 - - - 0.2336 - 2.031 0.518 - 227.7 1 2 0 0.0003 10 0 0 0 4.86E+06 7.35E+06 - - - 4.8446 0.9999 221125_WJC_METTL3_EV_vs_WT_F01.21263.21263.2 0.0029 22-Dec R.LFQVEYAIEAIK[136.11].L sp|P28066|PSA5_HUMAN 1 1430.7901 0.7 8644 21263 2 1430.791277 716.4023 Proteasome subunit alpha type-5 OS=Homo sapiens OX=9606 GN=PSMA5 PE=1 SV=3 4.53 3867.4 - 208159 - - - 0.845 - 2.507 0.468 - 423.1 1 2 0 0.0012 12 0 0 0 1.84E+06 2.62E+06 - - - 4.9155 0.9999 221125_WJC_METTL3_EV_vs_WT_F01.21264.21264.2 0.000132 16/28 R.TIAIIAEGIPEALTR[166.11].K sp|P53396|ACLY_HUMAN 1 1576.9064 0.77 8645 21264 2 1576.906084 789.4605 ATP-citrate synthase OS=Homo sapiens OX=9606 GN=ACLY PE=1 SV=3 4.53 3867.6 - 195269 - - - -0.1864 - 2.767 0.448 - 852.9 1 2 0 -0.0003 15 0 0 0 1.81E+06 2.34E+06 - - - 4.8521 0.9997 221125_WJC_METTL3_EV_vs_WT_F01.21266.21266.2 4.60E-05 28-Dec R.TIAIIAEGIPEALTR.K sp|P53396|ACLY_HUMAN 1 1566.8981 0.77 8647 21266 2 1566.901242 784.4563 ATP-citrate synthase OS=Homo sapiens OX=9606 GN=ACLY PE=1 SV=3 4.53 3867.8 - 190038 - - - 2.0001 - 2.64 0.487 - 473.6 1 2 0 0.0031 15 0 0 0 1.81E+06 2.34E+06 - - - 5.0237 0.9996 221125_WJC_METTL3_EV_vs_WT_F01.21272.21272.2 0.00617 16-Sep R.YLDVSILGK[136.11].F sp|Q86U44|MTA70_HUMAN 1 1014.5841 0.07 8652 21272 2 1014.585262 508.2993 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 5.83 3868.6 - 2.35E+07 - - - 1.1473 - 1.697 0.437 - 190.9 1 2 0 0.0012 9 0 0 0 5.07E+06 7.48E+07 - - - 3.7983 0.9998 221125_WJC_METTL3_EV_vs_WT_F01.21274.21274.2 2.58E-05 20-Nov R.EALDVLGAVLK[136.11].A "sp|Q92552|RT27_HUMAN,tr|G5EA06|G5EA06_HUMAN,tr|D6RH20|D6RH20_HUMAN" 3 1134.674 0.95 8654 21274 2 1134.674945 568.3443 "28S ribosomal protein S27, mitochondrial OS=Homo sapiens OX=9606 GN=MRPS27 PE=1 SV=3" 4.37 3868.8 - 2.31E+06 - - - 0.8549 - 2.157 0.496 - 437.6 1 2 0 0.001 11 0 0 0 2.18E+07 2.28E+07 - - - 4.7837 0.9998 221125_WJC_METTL3_EV_vs_WT_F01.21275.21275.2 4.68E-05 20-Nov R.EALDVLGAVLK.A "sp|Q92552|RT27_HUMAN,tr|G5EA06|G5EA06_HUMAN,tr|D6RH20|D6RH20_HUMAN" 3 1126.6598 0.96 8655 21275 2 1126.661024 564.3372 "28S ribosomal protein S27, mitochondrial OS=Homo sapiens OX=9606 GN=MRPS27 PE=1 SV=3" 4.37 3868.9 - 2.04E+06 - - - 1.1086 - 2.162 0.468 - 409 1 2 0 0.0012 11 0 0 0 2.19E+07 2.29E+07 - - - 4.5831 0.9978 221125_WJC_METTL3_EV_vs_WT_F01.21277.21277.2 0.00496 22-Sep R.LGAPGFAWEPFR[166.11].G "sp|Q9HCM7|FBSL_HUMAN,tr|A0A3B3IRR3|A0A3B3IRR3_HUMAN,tr|A0A7P0Z485|A0A7P0Z485_HUMAN" 3 1356.6854 1.7 8657 21277 2 1356.680868 679.35 Fibrosin-1-like protein OS=Homo sapiens OX=9606 GN=FBRSL1 PE=1 SV=4 6 3869.1 - 517781 - - - -3.3604 - 2.066 0.322 - 344.7 1 2 0 -0.0046 12 0 0 0 2.72E+06 1.60E+06 - - - 3.3271 0.9998 221125_WJC_METTL3_EV_vs_WT_F01.21279.21279.2 0.0208 28-Jul K.IIEEDDAYDFSTDYV.- sp|Q9BVP2|GNL3_HUMAN 1 1793.752 - 8659 21279 2 1793.752806 897.8833 Guanine nucleotide-binding protein-like 3 OS=Homo sapiens OX=9606 GN=GNL3 PE=1 SV=2 3.25 3869.3 - 410581 - - - 0.4733 - 1.68 0.525 - 59.4 1 2 0 0.0008 15 0 0 0 - - - - - 4.1939 0.9999 221125_WJC_METTL3_EV_vs_WT_F01.21280.21280.2 3.13E-06 18-Sep K.QEVPIIIVFR.A "sp|P30876|RPB2_HUMAN,tr|C9J4M6|C9J4M6_HUMAN,tr|C9J2Y9|C9J2Y9_HUMAN" 3 1212.723 0.97 8660 21280 2 1212.722841 607.3688 DNA-directed RNA polymerase II subunit RPB2 OS=Homo sapiens OX=9606 GN=POLR2B PE=1 SV=1 6 3869.5 - 385595 - - - -0.1674 - 2.026 0.488 - 231.1 1 2 0 -0.0002 10 0 0 0 6.06E+06 6.23E+06 - - - 4.6161 0.9949 221125_WJC_METTL3_EV_vs_WT_F01.21281.21281.2 0.00316 18-Jul K.EYLPFLNTLK[136.11].K "sp|O95163|ELP1_HUMAN,tr|A0A6Q8PFB7|A0A6Q8PFB7_HUMAN,tr|A0A6Q8PFH9|A0A6Q8PFH9_HUMAN,tr|A0A6Q8PH48|A0A6Q8PH48_HUMAN,tr|A0A6Q8PHC9|A0A6Q8PHC9_HUMAN,tr|A0A6Q8PHI5|A0A6Q8PHI5_HUMAN,tr|A0A6Q8PF66|A0A6Q8PF66_HUMAN,tr|A0A6Q8PGW3|A0A6Q8PGW3_HUMAN,tr|A0A6Q8PG86|A0A6Q8PG86_HUMAN,tr|A0A6Q8PEX6|A0A6Q8PEX6_HUMAN,tr|F5H2T0|F5H2T0_HUMAN,tr|A0A6Q8PHF4|A0A6Q8PHF4_HUMAN" 12 1244.6896 2.42 8661 21281 2 1244.692599 623.3521 Elongator complex protein 1 OS=Homo sapiens OX=9606 GN=ELP1 PE=1 SV=3 6.1 3869.6 - 340157 - - - 2.3894 - 1.361 0.273 - 123.2 1 2 0 0.003 10 0 0 0 4.57E+06 1.89E+06 - - - 1.9168 0.9999 221125_WJC_METTL3_EV_vs_WT_F01.21284.21284.2 5.02E-06 22-Dec R.EVAAGYLVPLLR[166.11].S sp|Q13395|TARB1_HUMAN 1 1309.7633 0.77 8664 21284 2 1309.763918 655.8889 Probable methyltransferase TARBP1 OS=Homo sapiens OX=9606 GN=TARBP1 PE=1 SV=1 6.1 3870 - 183161 - - - 0.439 - 2.593 0.501 - 672.8 1 2 0 0.0006 12 0 0 0 8.70E+05 1.13E+06 - - - 5.2482 0.9997 221125_WJC_METTL3_EV_vs_WT_F01.21293.21293.2 0.000159 18-Sep K.C[160.03]MQLTDFILK.F "sp|P50914|RL14_HUMAN,tr|E7EPB3|E7EPB3_HUMAN" 2 1267.6305 0.67 8671 21293 2 1267.632174 634.8225 60S ribosomal protein L14 OS=Homo sapiens OX=9606 GN=RPL14 PE=1 SV=4 5.83 3871.2 - 991116 - - - 1.3474 - 1.832 0.452 - 215.5 1 2 0 0.0017 10 0 0 0 4.92E+06 7.35E+06 - - - 4.0688 0.9997 221125_WJC_METTL3_EV_vs_WT_F01.21294.21294.2 0.000807 18-Oct K.QEVPIIIVFR[166.11].A "sp|P30876|RPB2_HUMAN,tr|C9J4M6|C9J4M6_HUMAN,tr|C9J2Y9|C9J2Y9_HUMAN" 3 1222.7313 0.98 8672 21294 2 1222.733547 612.3729 DNA-directed RNA polymerase II subunit RPB2 OS=Homo sapiens OX=9606 GN=POLR2B PE=1 SV=1 6 3871.3 - 872356 - - - 1.8262 - 2.001 0.502 - 392.7 1 2 0 0.0022 10 0 0 0 6.10E+06 6.23E+06 - - - 4.6843 0.9956 221125_WJC_METTL3_EV_vs_WT_F01.21298.21298.2 0.396 14-Aug R.VDEIIWVK[136.11].T sp|Q86U44|MTA70_HUMAN 1 1008.5735 0.05 8676 21298 2 1008.575844 505.294 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 4.37 3871.9 - 488248 - - - 2.2914 - 1.59 0.21 - 203.3 1 2 0 0.0023 8 0 0 0 2.48E+05 4.67E+06 - - - 1.9899 0.9947 221125_WJC_METTL3_EV_vs_WT_F01.21302.21302.2 0.196 22-Sep R.LFQVEYAIEAIK.L sp|P28066|PSA5_HUMAN 1 1422.7759 0.7 8680 21302 2 1422.778612 712.3952 Proteasome subunit alpha type-5 OS=Homo sapiens OX=9606 GN=PSMA5 PE=1 SV=3 4.53 3872.4 - 302376 - - - 1.9286 - 1.475 0.215 - 189.8 1 2 0 0.0027 12 0 0 0 1.84E+06 2.62E+06 - - - 1.6508 0.9895 221125_WJC_METTL3_EV_vs_WT_F01.21317.21317.2 0.324 20-Jun R.DGAGLQAAWRR.Q "sp|A4GXA9|EME2_HUMAN,tr|H3BSZ6|H3BSZ6_HUMAN,tr|H3BV62|H3BV62_HUMAN" 3 1199.616 57.3 8694 21317 2 1199.618211 600.8153 Probable crossover junction endonuclease EME2 OS=Homo sapiens OX=9606 GN=EME2 PE=1 SV=3 9.6 3874.2 - 938329 - - - 1.8823 - 1.427 0.169 - 141 2 2 0 0.0023 11 0 0 0 5.18E+06 9.05E+04 - - - 1.116 0.9992 221125_WJC_METTL3_EV_vs_WT_F01.21320.21320.2 0.00107 18-Nov K.LFEISDIVIK[136.11].D sp|Q9NSD9|SYFB_HUMAN 1 1183.6944 0.6 8697 21320 2 1183.698237 592.8545 Phenylalanine--tRNA ligase beta subunit OS=Homo sapiens OX=9606 GN=FARSB PE=1 SV=3 4.37 3874.6 - 634319 - - - 3.2618 - 2.103 0.475 - 345.3 1 2 0 0.0039 10 0 0 0 1.48E+06 2.45E+06 - - - 4.6231 0.9996 221125_WJC_METTL3_EV_vs_WT_F01.21327.21327.2 0.0523 20-Oct K.DSLIIIDELGR.G "sp|P43246|MSH2_HUMAN,tr|A0A2R8YG02|A0A2R8YG02_HUMAN,tr|E9PHA6|E9PHA6_HUMAN,tr|A0A2R8YFH0|A0A2R8YFH0_HUMAN,tr|A0A2R8Y6P0|A0A2R8Y6P0_HUMAN,tr|A0A2R8Y713|A0A2R8Y713_HUMAN" 6 1242.682 1.61 8704 21327 2 1242.683868 622.3483 DNA mismatch repair protein Msh2 OS=Homo sapiens OX=9606 GN=MSH2 PE=1 SV=1 4.03 3875.5 - 265757 - - - 1.5298 - 2.017 0.397 - 280.4 1 2 0 0.0019 11 0 0 0 2.76E+06 1.71E+06 - - - 3.8707 0.9942 221125_WJC_METTL3_EV_vs_WT_F01.21331.21331.2 0.00487 24-Aug R.LDQLIYIPLPDEK[136.11].S "sp|P55072|TERA_HUMAN,tr|A0A7P0Z4C6|A0A7P0Z4C6_HUMAN,tr|A0A7P0T8Q5|A0A7P0T8Q5_HUMAN,tr|C9JUP7|C9JUP7_HUMAN,tr|A0A7P0TAW3|A0A7P0TAW3_HUMAN,tr|A0A7I2V540|A0A7I2V540_HUMAN,tr|A0A7P0T8A3|A0A7P0T8A3_HUMAN,tr|A0A7P0TAQ1|A0A7P0TAQ1_HUMAN" 8 1563.864 1.01 8708 21331 2 1563.869257 782.9393 Transitional endoplasmic reticulum ATPase OS=Homo sapiens OX=9606 GN=VCP PE=1 SV=4 4.03 3876 - 153969 - - - 3.3865 - 1.598 0.293 - 158.5 1 2 0 0.0053 13 0 0 0 6.95E+05 6.91E+05 - - - 2.4065 1 221125_WJC_METTL3_EV_vs_WT_F01.21340.21340.3 6.83E-11 19/68 K.VGLTNYAAAYC[160.03]TGLLLAR[166.11].R "sp|P46777|RL5_HUMAN,tr|A0A2R8Y6J3|A0A2R8Y6J3_HUMAN,tr|A0A2R8Y4A2|A0A2R8Y4A2_HUMAN,tr|Q5T7N0|Q5T7N0_HUMAN" 4 1936.0116 -1 8716 21340 3 1936.014683 646.3445 60S ribosomal protein L5 OS=Homo sapiens OX=9606 GN=RPL5 PE=1 SV=3 8.17 3877 - 594059 - - - 1.5981 - 2.928 0.623 - 383.5 1 2 0 0.0031 18 0 0 0 0.00E+00 0.00E+00 - - - 8.1601 0.9998 221125_WJC_METTL3_EV_vs_WT_F01.21344.21344.2 0.000361 24-Nov K.VFSATLGLVDIVK[136.11].G "sp|P09874|PARP1_HUMAN,tr|A0A7I2V3E1|A0A7I2V3E1_HUMAN" 2 1368.8108 1.03 8720 21344 2 1368.812262 685.4127 Poly [ADP-ribose] polymerase 1 OS=Homo sapiens OX=9606 GN=PARP1 PE=1 SV=4 5.81 3877.4 - 434042 - - - 1.0659 - 2.342 0.511 - 285.1 1 2 0 0.0015 13 0 0 0 1.16E+07 1.13E+07 - - - 4.9989 0.9988 221125_WJC_METTL3_EV_vs_WT_F01.21346.21346.3 3.04E-05 Nov-68 K.VGLTNYAAAYC[160.03]TGLLLAR.R "sp|P46777|RL5_HUMAN,tr|A0A2R8Y6J3|A0A2R8Y6J3_HUMAN,tr|A0A2R8Y4A2|A0A2R8Y4A2_HUMAN,tr|Q5T7N0|Q5T7N0_HUMAN" 4 1926.0033 0.59 8722 21346 3 1926.011781 643.0084 60S ribosomal protein L5 OS=Homo sapiens OX=9606 GN=RPL5 PE=1 SV=3 8.17 3877.7 - 343712 - - - 4.3936 - 2.003 0.431 - 85.2 1 2 0 0.0085 18 0 0 0 1.04E+06 1.75E+06 - - - 5.0726 1 221125_WJC_METTL3_EV_vs_WT_F01.21347.21347.2 1.48E-07 14/34 K.VGLTNYAAAYC[160.03]TGLLLAR[166.11].R "sp|P46777|RL5_HUMAN,tr|A0A2R8Y6J3|A0A2R8Y6J3_HUMAN,tr|A0A2R8Y4A2|A0A2R8Y4A2_HUMAN,tr|Q5T7N0|Q5T7N0_HUMAN" 4 1936.0116 -1 8723 21347 2 1936.013508 969.0131 60S ribosomal protein L5 OS=Homo sapiens OX=9606 GN=RPL5 PE=1 SV=3 8.17 3877.8 - 297204 - - - 0.9912 - 2.736 0.615 - 582.8 1 2 0 0.0019 18 0 0 0 0.00E+00 0.00E+00 - - - 6.0573 1 221125_WJC_METTL3_EV_vs_WT_F01.21349.21349.2 4.04E-11 Nov-34 K.VGLTNYAAAYC[160.03]TGLLLAR.R "sp|P46777|RL5_HUMAN,tr|A0A2R8Y6J3|A0A2R8Y6J3_HUMAN,tr|A0A2R8Y4A2|A0A2R8Y4A2_HUMAN,tr|Q5T7N0|Q5T7N0_HUMAN" 4 1926.0033 -1 8725 21349 2 1926.006263 964.0089 60S ribosomal protein L5 OS=Homo sapiens OX=9606 GN=RPL5 PE=1 SV=3 8.17 3878.1 - 208840 - - - 1.5286 - 2.689 0.63 - 353.8 1 2 0 0.0029 18 0 0 0 0.00E+00 0.00E+00 - - - 6.1252 0.999 221125_WJC_METTL3_EV_vs_WT_F01.21350.21350.2 2.11E-06 24-Nov K.TVQTAVFLYSLYK.E "sp|Q14839|CHD4_HUMAN,tr|A0A2R8Y4X2|A0A2R8Y4X2_HUMAN,tr|A0A2U3TZM0|A0A2U3TZM0_HUMAN,tr|A0A2R8Y685|A0A2R8Y685_HUMAN,tr|A0A2R8Y445|A0A2R8Y445_HUMAN,tr|A0A2R8YD40|A0A2R8YD40_HUMAN,tr|A0A2R8Y5J0|A0A2R8Y5J0_HUMAN,tr|A0A2R8Y425|A0A2R8Y425_HUMAN,tr|A0A2R8YFK9|A0A2R8YFK9_HUMAN,tr|A0A2R8Y8B3|A0A2R8Y8B3_HUMAN,tr|A0A2R8Y8C1|A0A2R8Y8C1_HUMAN,tr|A0A0C4DGG9|A0A0C4DGG9_HUMAN,tr|A0A2R8YFD8|A0A2R8YFD8_HUMAN,tr|A0A2R8YDW2|A0A2R8YDW2_HUMAN,tr|A0A2R8Y5Z7|A0A2R8Y5Z7_HUMAN,tr|F5GWX5|F5GWX5_HUMAN,tr|A0A2R8YER1|A0A2R8YER1_HUMAN,tr|A0A2R8Y521|A0A2R8Y521_HUMAN,tr|A0A2R8YDJ9|A0A2R8YDJ9_HUMAN,tr|A0A2R8Y212|A0A2R8Y212_HUMAN" 20 1531.8286 -1 8726 21350 2 1531.835153 766.9216 Chromodomain-helicase-DNA-binding protein 4 OS=Homo sapiens OX=9606 GN=CHD4 PE=1 SV=2 8.17 3878.2 - 192599 - - - 4.257 - 2.461 0.587 - 286.6 1 2 0 0.0065 13 0 0 0 0.00E+00 0.00E+00 - - - 5.6859 0.8367 221125_WJC_METTL3_EV_vs_WT_F01.21355.21355.2 0.0199 22-Jul R.DYLHLPPEIVPA.T "sp|Q9NQ39|RS10L_HUMAN,sp|P46783|RS10_HUMAN,tr|A0A2R8Y6L3|A0A2R8Y6L3_HUMAN,tr|F6U211|F6U211_HUMAN,tr|A0A1W2PQS6|A0A1W2PQS6_HUMAN,tr|A0A2R8YFH6|A0A2R8YFH6_HUMAN,tr|A0A2R8Y7H1|A0A2R8Y7H1_HUMAN,tr|S4R435|S4R435_HUMAN" 8 1362.7184 - 8730 21355 2 1362.720322 682.3665 Putative 40S ribosomal protein S10-like OS=Homo sapiens OX=9606 GN=RPS10P5 PE=5 SV=1 4.35 3878.8 - 1.70E+06 - - - 1.4449 - 1.542 0.221 - 110 1 1 0 0.002 12 0 0 0 - - - - - 1.8122 1 221125_WJC_METTL3_EV_vs_WT_F01.21358.21358.2 2.61E-07 24-Dec K.VFSATLGLVDIVK.G "sp|P09874|PARP1_HUMAN,tr|A0A7I2V3E1|A0A7I2V3E1_HUMAN" 2 1360.7966 1.03 8733 21358 2 1360.800105 681.4056 Poly [ADP-ribose] polymerase 1 OS=Homo sapiens OX=9606 GN=PARP1 PE=1 SV=4 5.81 3879.1 - 1.70E+06 - - - 2.5735 - 2.523 0.587 - 407.9 1 2 0 0.0035 13 0 0 0 1.16E+07 1.13E+07 - - - 5.7507 0.9997 221125_WJC_METTL3_EV_vs_WT_F01.21361.21361.2 1.99E-05 24-Dec K.TVQTAVFLYSLYK[136.11].E "sp|Q14839|CHD4_HUMAN,tr|A0A2R8Y4X2|A0A2R8Y4X2_HUMAN,tr|A0A2U3TZM0|A0A2U3TZM0_HUMAN,tr|A0A2R8Y685|A0A2R8Y685_HUMAN,tr|A0A2R8Y445|A0A2R8Y445_HUMAN,tr|A0A2R8YD40|A0A2R8YD40_HUMAN,tr|A0A2R8Y5J0|A0A2R8Y5J0_HUMAN,tr|A0A2R8Y425|A0A2R8Y425_HUMAN,tr|A0A2R8YFK9|A0A2R8YFK9_HUMAN,tr|A0A2R8Y8B3|A0A2R8Y8B3_HUMAN,tr|A0A2R8Y8C1|A0A2R8Y8C1_HUMAN,tr|A0A0C4DGG9|A0A0C4DGG9_HUMAN,tr|A0A2R8YFD8|A0A2R8YFD8_HUMAN,tr|A0A2R8YDW2|A0A2R8YDW2_HUMAN,tr|A0A2R8Y5Z7|A0A2R8Y5Z7_HUMAN,tr|F5GWX5|F5GWX5_HUMAN,tr|A0A2R8YER1|A0A2R8YER1_HUMAN,tr|A0A2R8Y521|A0A2R8Y521_HUMAN,tr|A0A2R8YDJ9|A0A2R8YDJ9_HUMAN,tr|A0A2R8Y212|A0A2R8Y212_HUMAN" 20 1539.8428 -1 8736 21361 2 1539.84507 770.9287 Chromodomain-helicase-DNA-binding protein 4 OS=Homo sapiens OX=9606 GN=CHD4 PE=1 SV=2 8.17 3879.4 - 705167 - - - 1.4534 - 2.591 0.374 - 347.5 1 2 0 0.0022 13 0 0 0 0.00E+00 0.00E+00 - - - 4.2461 0.9987 221125_WJC_METTL3_EV_vs_WT_F01.21362.21362.2 0.0044 14-Sep R.ILEFFGLK[136.11].K "sp|P07237|PDIA1_HUMAN,tr|A0A7P0TA97|A0A7P0TA97_HUMAN,tr|A0A7P0T8C0|A0A7P0T8C0_HUMAN,tr|H7BZ94|H7BZ94_HUMAN,tr|A0A7P0TA71|A0A7P0TA71_HUMAN,tr|I3L4M2|I3L4M2_HUMAN,tr|A0A7P0T9D6|A0A7P0T9D6_HUMAN,tr|A0A7P0T9K9|A0A7P0T9K9_HUMAN,tr|H0Y3Z3|H0Y3Z3_HUMAN,tr|A0A7P0TA35|A0A7P0TA35_HUMAN,tr|I3L514|I3L514_HUMAN,tr|A0A7P0TB26|A0A7P0TB26_HUMAN,tr|A0A7P0T9U6|A0A7P0T9U6_HUMAN,tr|I3L0S0|I3L0S0_HUMAN,tr|I3L3P5|I3L3P5_HUMAN,tr|A0A7P0T8J3|A0A7P0T8J3_HUMAN,tr|A0A7P0T8X1|A0A7P0T8X1_HUMAN" 17 973.5728 1.38 8737 21362 2 973.575389 487.7937 Protein disulfide-isomerase OS=Homo sapiens OX=9606 GN=P4HB PE=1 SV=3 6 3879.5 - 697185 - - - 2.6541 - 1.765 0.348 - 211.7 1 2 0 0.0026 8 0 0 0 3.33E+07 2.41E+07 - - - 3.324 0.9979 221125_WJC_METTL3_EV_vs_WT_F01.21363.21363.2 0.0524 14-Aug R.ILEFFGLK.K "sp|P07237|PDIA1_HUMAN,tr|A0A7P0TA97|A0A7P0TA97_HUMAN,tr|A0A7P0T8C0|A0A7P0T8C0_HUMAN,tr|H7BZ94|H7BZ94_HUMAN,tr|A0A7P0TA71|A0A7P0TA71_HUMAN,tr|I3L4M2|I3L4M2_HUMAN,tr|A0A7P0T9D6|A0A7P0T9D6_HUMAN,tr|A0A7P0T9K9|A0A7P0T9K9_HUMAN,tr|H0Y3Z3|H0Y3Z3_HUMAN,tr|A0A7P0TA35|A0A7P0TA35_HUMAN,tr|I3L514|I3L514_HUMAN,tr|A0A7P0TB26|A0A7P0TB26_HUMAN,tr|A0A7P0T9U6|A0A7P0T9U6_HUMAN,tr|I3L0S0|I3L0S0_HUMAN,tr|I3L3P5|I3L3P5_HUMAN,tr|A0A7P0T8J3|A0A7P0T8J3_HUMAN,tr|A0A7P0T8X1|A0A7P0T8X1_HUMAN" 17 965.5586 1.38 8738 21363 2 965.56092 483.7866 Protein disulfide-isomerase OS=Homo sapiens OX=9606 GN=P4HB PE=1 SV=3 6 3879.7 - 640938 - - - 2.3976 - 1.535 0.322 - 159.1 1 2 0 0.0023 8 0 0 0 3.33E+07 2.41E+07 - - - 2.711 1 221125_WJC_METTL3_EV_vs_WT_F01.21365.21365.2 2.50E-08 13/20 K.DPWDAVLLEER[166.11].S "sp|O00443|P3C2A_HUMAN,tr|A0A0C4DGF9|A0A0C4DGF9_HUMAN" 2 1351.6648 1.61 8740 21365 2 1351.666329 676.8397 Phosphatidylinositol 4-phosphate 3-kinase C2 domain-containing subunit alpha OS=Homo sapiens OX=9606 GN=PIK3C2A PE=1 SV=2 3.92 3879.9 - 355747 - - - 1.1674 - 2.679 0.58 - 727.8 1 2 0 0.0016 11 0 0 0 6.95E+06 4.32E+06 - - - 5.9902 0.9999 221125_WJC_METTL3_EV_vs_WT_F01.21367.21367.2 0.000127 24-Nov K.LLLDTFEYQGLVK[136.11].H "sp|Q7Z7K6|CENPV_HUMAN,tr|A0A0M3HER2|A0A0M3HER2_HUMAN" 2 1545.8534 -1 8742 21367 2 1545.852533 773.934 Centromere protein V OS=Homo sapiens OX=9606 GN=CENPV PE=1 SV=1 4.37 3880.2 - 280144 - - - -0.5583 - 2.126 0.49 - 295.6 1 2 0 -0.0009 13 0 0 0 0.00E+00 0.00E+00 - - - 4.5957 0.9995 221125_WJC_METTL3_EV_vs_WT_F01.21371.21371.2 0.000169 22-Aug R.LFPPQWIC[160.03]C[160.03]DIR.Y sp|Q86U44|MTA70_HUMAN 1 1603.7639 0.02 8746 21371 2 1603.767167 802.8892 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 5.82 3880.7 - 196000 - - - 2.0121 - 1.635 0.505 - 172.6 1 2 0 0.0032 12 0 0 0 3.95E+06 2.19E+08 - - - 4.0635 0.9996 221125_WJC_METTL3_EV_vs_WT_F01.21372.21372.2 0.00607 24-Nov K.ALEVAEYLTPVLK[136.11].E "sp|Q9NT62|ATG3_HUMAN,tr|F8WDI0|F8WDI0_HUMAN" 2 1452.8319 -1 8747 21372 2 1452.834445 727.4232 Ubiquitin-like-conjugating enzyme ATG3 OS=Homo sapiens OX=9606 GN=ATG3 PE=1 SV=1 4.53 3880.8 - 175171 - - - 1.729 - 2.313 0.381 - 411.9 1 2 0 0.0025 13 0 0 0 0.00E+00 0.00E+00 - - - 4.0064 0.885 221125_WJC_METTL3_EV_vs_WT_F01.21378.21378.2 0.169 14-Jul N.GVSQLIQR[166.11].E sp|P48201|AT5G3_HUMAN 1 909.5271 0.9 8752 21378 2 909.528943 455.7708 "ATP synthase F(0) complex subunit C3, mitochondrial OS=Homo sapiens OX=9606 GN=ATP5MC3 PE=1 SV=1" 9.75 3881.7 - 1.06E+06 - - - 1.9878 - 1.59 0.269 - 184.4 1 1 0 0.0018 8 0 0 0 2.03E+07 2.26E+07 - - - 2.4259 0.9992 221125_WJC_METTL3_EV_vs_WT_F01.21379.21379.2 0.000737 16-Sep R.DIDAFWLQR.Q "sp|O75643|U520_HUMAN,tr|A0A494C1A5|A0A494C1A5_HUMAN" 2 1162.5771 1.84 8753 21379 2 1162.580469 582.2958 U5 small nuclear ribonucleoprotein 200 kDa helicase OS=Homo sapiens OX=9606 GN=SNRNP200 PE=1 SV=2 4.21 3881.8 - 981249 - - - 2.891 - 1.963 0.437 - 301 1 2 0 0.0034 9 0 0 0 2.14E+07 1.16E+07 - - - 4.2189 0.9274 221125_WJC_METTL3_EV_vs_WT_F01.21381.21381.2 2.45E-07 24-Nov K.VIHDNFGIVEGLM.T "sp|P04406|G3P_HUMAN,tr|E7EUT5|E7EUT5_HUMAN" 2 1442.7228 - 8755 21381 2 1442.729386 722.3687 Glyceraldehyde-3-phosphate dehydrogenase OS=Homo sapiens OX=9606 GN=GAPDH PE=1 SV=3 4.35 3882.1 - 846231 - - - 4.5747 - 2.376 0.572 - 489 1 1 0 0.0066 13 0 0 0 - - - - - 5.4848 0.9998 221125_WJC_METTL3_EV_vs_WT_F01.21382.21382.2 0.000136 15/22 K.IILDLISESPIK[136.11].G "sp|P61978|HNRPK_HUMAN,tr|Q5T6W2|Q5T6W2_HUMAN" 2 1347.8105 1.21 8756 21382 2 1347.813669 674.9125 Heterogeneous nuclear ribonucleoprotein K OS=Homo sapiens OX=9606 GN=HNRNPK PE=1 SV=1 4.37 3882.2 - 841090 - - - 2.3742 - 2.863 0.522 - 735.8 1 2 0 0.0032 12 0 0 0 6.19E+07 5.10E+07 - - - 5.6631 0.8974 221125_WJC_METTL3_EV_vs_WT_F01.21383.21383.2 0.263 14-Jul N.GVSQLIQR.E sp|P48201|AT5G3_HUMAN 1 899.5189 0.9 8757 21383 2 899.520748 450.7667 "ATP synthase F(0) complex subunit C3, mitochondrial OS=Homo sapiens OX=9606 GN=ATP5MC3 PE=1 SV=1" 9.75 3882.3 - 806282 - - - 2.0933 - 1.703 0.265 - 198.6 1 1 0 0.0019 8 0 0 0 2.03E+07 2.26E+07 - - - 2.6034 0.993 221125_WJC_METTL3_EV_vs_WT_F01.21388.21388.2 0.037 22-Nov K.AVEIEELTYIIK.Q "sp|Q13190|STX5_HUMAN,tr|H7C3X5|H7C3X5_HUMAN,tr|E9PNU4|E9PNU4_HUMAN" 3 1419.7861 -1 8762 21388 2 1419.792536 710.9003 Syntaxin-5 OS=Homo sapiens OX=9606 GN=STX5 PE=1 SV=2 4.25 3883 - 374550 - - - 4.5345 - 1.912 0.309 - 387 1 2 0 0.0064 12 0 0 0 0.00E+00 0.00E+00 - - - 3.0266 0.9987 221125_WJC_METTL3_EV_vs_WT_F01.21390.21390.2 0.00239 14-Oct K.LYDFYLFK.C sp|Q2TAL8|QRIC1_HUMAN 1 1107.5641 -1 8764 21390 2 1107.567405 554.7893 Transcriptional regulator QRICH1 OS=Homo sapiens OX=9606 GN=QRICH1 PE=1 SV=1 5.83 3883.2 - 269305 - - - 2.9985 - 1.648 0.424 - 251.1 1 2 0 0.0033 8 0 0 0 0.00E+00 0.00E+00 - - - 3.6783 0.9998 221125_WJC_METTL3_EV_vs_WT_F01.21392.21392.2 1.10E-05 28-Jul R.VYEIPGLEPITFAGK.M "sp|Q9BZE1|RM37_HUMAN,tr|S4R369|S4R369_HUMAN" 2 1632.8763 1.71 8766 21392 2 1632.879179 817.4454 "39S ribosomal protein L37, mitochondrial OS=Homo sapiens OX=9606 GN=MRPL37 PE=1 SV=2" 4.53 3883.5 - 225441 - - - 1.757 - 1.812 0.581 - 118 1 2 0 0.0029 15 0 0 0 2.03E+06 1.19E+06 - - - 4.7928 0.9988 221125_WJC_METTL3_EV_vs_WT_F01.21394.21394.3 0.000909 Sep-48 K.VSASPLLYTLIEK[136.11].T "sp|P02786|TFR1_HUMAN,tr|G3V0E5|G3V0E5_HUMAN" 2 1440.8319 -1 8768 21394 3 1440.835153 481.2846 Transferrin receptor protein 1 OS=Homo sapiens OX=9606 GN=TFRC PE=1 SV=2 5.97 3883.7 - 145816 - - - 2.2348 - 1.856 0.317 - 84.3 1 2 0 0.0032 13 0 0 0 0.00E+00 0.00E+00 - - - 3.7501 0.9998 221125_WJC_METTL3_EV_vs_WT_F01.21399.21399.2 0.00423 15/22 K.IILDLISESPIK.G "sp|P61978|HNRPK_HUMAN,tr|Q5T6W2|Q5T6W2_HUMAN" 2 1339.7963 1.2 8772 21399 2 1339.798242 670.9054 Heterogeneous nuclear ribonucleoprotein K OS=Homo sapiens OX=9606 GN=HNRNPK PE=1 SV=1 4.37 3884.3 - 4.30E+06 - - - 1.4726 - 2.717 0.471 - 756.2 1 2 0 0.002 12 0 0 0 6.08E+07 5.07E+07 - - - 5.1491 0.9994 221125_WJC_METTL3_EV_vs_WT_F01.21400.21400.2 0.000467 16-Sep R.DIDAFWLQR[166.11].Q "sp|O75643|U520_HUMAN,tr|A0A494C1A5|A0A494C1A5_HUMAN" 2 1172.5854 1.83 8773 21400 2 1172.587651 587.3 U5 small nuclear ribonucleoprotein 200 kDa helicase OS=Homo sapiens OX=9606 GN=SNRNP200 PE=1 SV=2 4.21 3884.3 - 4.01E+06 - - - 1.9385 - 1.996 0.374 - 273.9 1 2 0 0.0023 9 0 0 0 2.15E+07 1.17E+07 - - - 3.8022 0.9998 221125_WJC_METTL3_EV_vs_WT_F01.21402.21402.2 0.000261 14/24 K.LEVAPISDIIAIK[136.11].S "sp|P13804|ETFA_HUMAN,tr|H0YK49|H0YK49_HUMAN,tr|H0YL12|H0YL12_HUMAN,tr|H0YKF0|H0YKF0_HUMAN,tr|H0YLU7|H0YLU7_HUMAN,tr|H0YNX6|H0YNX6_HUMAN" 6 1388.837 1.72 8775 21402 2 1388.838717 695.4258 "Electron transfer flavoprotein subunit alpha, mitochondrial OS=Homo sapiens OX=9606 GN=ETFA PE=1 SV=1" 4.37 3884.5 - 1.03E+06 - - - 1.2233 - 2.43 0.503 - 511.3 1 2 0 0.0017 13 0 0 0 1.92E+07 1.11E+07 - - - 5.0344 1 221125_WJC_METTL3_EV_vs_WT_F01.21404.21404.2 9.28E-10 15/24 K.VSASPLLYTLIEK[136.11].T "sp|P02786|TFR1_HUMAN,tr|G3V0E5|G3V0E5_HUMAN" 2 1440.8319 1.37 8777 21404 2 1440.833328 721.4232 Transferrin receptor protein 1 OS=Homo sapiens OX=9606 GN=TFRC PE=1 SV=2 5.97 3884.8 - 942108 - - - 0.9682 - 3.073 0.609 - 1085.1 1 2 0 0.0014 13 0 0 0 4.56E+06 3.32E+06 - - - 6.42 0.9996 221125_WJC_METTL3_EV_vs_WT_F01.21409.21409.2 0.00621 18-Nov R.SLGPVELLLR.G "sp|Q16512|PKN1_HUMAN,tr|K7EKY9|K7EKY9_HUMAN,tr|K7EM57|K7EM57_HUMAN" 3 1095.6652 2.82 8782 21409 2 1095.667368 548.8399 Serine\threonine-protein kinase N1 OS=Homo sapiens OX=9606 GN=PKN1 PE=1 SV=2 5.72 3885.3 - 572292 - - - 1.9833 - 1.955 0.438 - 413.7 1 2 0 0.0022 10 0 0 0 1.17E+07 4.16E+06 - - - 4.1466 0.9997 221125_WJC_METTL3_EV_vs_WT_F01.21411.21411.2 0.000285 20-Sep K.SFVLPSWMVEK.M "sp|Q9H147|TDIF1_HUMAN,tr|H7C1M5|H7C1M5_HUMAN,tr|H7C1J2|H7C1J2_HUMAN" 3 1321.674 0.81 8784 21411 2 1321.673892 661.8443 Deoxynucleotidyltransferase terminal-interacting protein 1 OS=Homo sapiens OX=9606 GN=DNTTIP1 PE=1 SV=2 5.72 3885.6 - 369857 - - - -0.1158 - 1.696 0.406 - 265.2 1 2 0 -0.0002 11 0 0 0 8.83E+05 1.09E+06 - - - 3.4688 0.9909 221125_WJC_METTL3_EV_vs_WT_F01.21416.21416.2 0.0171 14-Jul R.SWLLPVIR.D sp|Q5JTH9|RRP12_HUMAN 1 982.5964 -1 8789 21416 2 982.598011 492.3055 RRP12-like protein OS=Homo sapiens OX=9606 GN=RRP12 PE=1 SV=2 9.47 3886.2 - 325762 - - - 1.6528 - 1.484 0.12 - 209.8 1 2 0 0.0016 8 0 0 0 0.00E+00 0.00E+00 - - - 1.1173 0.9459 221125_WJC_METTL3_EV_vs_WT_F01.21418.21418.2 3.02 20-Apr K.SFVLPSWMVEK[136.11].M "sp|Q9H147|TDIF1_HUMAN,tr|H7C1M5|H7C1M5_HUMAN,tr|H7C1J2|H7C1J2_HUMAN" 3 1329.6882 0.79 8790 21418 2 1329.686926 665.8514 Deoxynucleotidyltransferase terminal-interacting protein 1 OS=Homo sapiens OX=9606 GN=DNTTIP1 PE=1 SV=2 5.72 3886.6 - 129087 - - - -0.992 - 1.05 0.079 - 52.1 2 2 0 -0.0013 11 0 0 0 9.70E+05 1.24E+06 - - - -0.3784 1 221125_WJC_METTL3_EV_vs_WT_F01.21421.21421.2 2.40E-09 26-Dec K.FGGDFLVYPGDPLR.F "sp|Q9BSV6|SEN34_HUMAN,tr|A0A590UJ73|A0A590UJ73_HUMAN,tr|E7EQB3|E7EQB3_HUMAN,tr|A0A590UJW4|A0A590UJW4_HUMAN" 4 1551.7722 0.19 8793 21421 2 1551.773255 776.8934 tRNA-splicing endonuclease subunit Sen34 OS=Homo sapiens OX=9606 GN=TSEN34 PE=1 SV=1 4.21 3886.9 - 887944 - - - 0.6934 - 2.714 0.601 - 328.7 1 2 0 0.0011 14 0 0 0 3.49E+06 1.83E+07 - - - 5.9851 0.9962 221125_WJC_METTL3_EV_vs_WT_F01.21427.21427.2 0.0105 14-Aug K.ENLLDFIK[136.11].H "sp|P07237|PDIA1_HUMAN,tr|A0A7P0TA97|A0A7P0TA97_HUMAN,tr|A0A7P0T8C0|A0A7P0T8C0_HUMAN,tr|H7BZ94|H7BZ94_HUMAN,tr|A0A7P0TA71|A0A7P0TA71_HUMAN,tr|I3L4M2|I3L4M2_HUMAN,tr|A0A7P0T9D6|A0A7P0T9D6_HUMAN,tr|A0A7P0T9K9|A0A7P0T9K9_HUMAN,tr|H0Y3Z3|H0Y3Z3_HUMAN,tr|A0A7P0Z4S2|A0A7P0Z4S2_HUMAN,tr|A0A7P0TA35|A0A7P0TA35_HUMAN,tr|I3L514|I3L514_HUMAN,tr|A0A7P0TB26|A0A7P0TB26_HUMAN,tr|A0A7P0T9U6|A0A7P0T9U6_HUMAN,tr|I3L0S0|I3L0S0_HUMAN,tr|I3L3P5|I3L3P5_HUMAN,tr|A0A7P0T8J3|A0A7P0T8J3_HUMAN,tr|A0A7P0Z4J0|A0A7P0Z4J0_HUMAN,tr|A0A7P0T8X1|A0A7P0T8X1_HUMAN" 19 998.5528 1.4 8799 21427 2 998.556439 500.2837 Protein disulfide-isomerase OS=Homo sapiens OX=9606 GN=P4HB PE=1 SV=3 4.37 3887.7 - 457215 - - - 3.6473 - 1.847 0.285 - 244.5 1 2 0 0.0036 8 0 0 0 3.79E+07 2.71E+07 - - - 2.9953 0.9991 221125_WJC_METTL3_EV_vs_WT_F01.21428.21428.2 0.00164 18-Sep R.SLGPVELLLR[166.11].G "sp|Q16512|PKN1_HUMAN,tr|K7EKY9|K7EKY9_HUMAN,tr|K7EM57|K7EM57_HUMAN" 3 1105.6735 2.73 8800 21428 2 1105.676006 553.844 Serine\threonine-protein kinase N1 OS=Homo sapiens OX=9606 GN=PKN1 PE=1 SV=2 5.72 3887.8 - 445773 - - - 2.2981 - 1.895 0.357 - 239 1 2 0 0.0025 10 0 0 0 1.14E+07 4.16E+06 - - - 3.4613 0.9998 221125_WJC_METTL3_EV_vs_WT_F01.21429.21429.2 4.83E-09 14/30 K.TFVNITPAEVGVLVGK[136.11].D "sp|P07737|PROF1_HUMAN,tr|I3L3D5|I3L3D5_HUMAN" 2 1650.9436 0.67 8801 21429 2 1650.944571 826.4791 Profilin-1 OS=Homo sapiens OX=9606 GN=PFN1 PE=1 SV=2 5.66 3887.9 - 412026 - - - 0.5833 - 2.561 0.438 - 450.1 1 2 0 0.001 16 0 0 0 1.00E+06 1.50E+06 - - - 4.5878 1 221125_WJC_METTL3_EV_vs_WT_F01.21430.21430.2 1.12E-08 13/26 N.SLTYSPFGDSPLFR.N "sp|P52948|NUP98_HUMAN,tr|A0A3B3ITD8|A0A3B3ITD8_HUMAN,tr|H0YEN4|H0YEN4_HUMAN,tr|H0YCR0|H0YCR0_HUMAN" 4 1585.7777 2.27 8802 21430 2 1585.779333 793.8961 Nuclear pore complex protein Nup98-Nup96 OS=Homo sapiens OX=9606 GN=NUP98 PE=1 SV=4 5.55 3888.1 - 374842 - - - 1.0556 - 2.625 0.606 - 483.3 1 1 0 0.0017 14 0 0 0 4.15E+06 1.83E+06 - - - 5.9382 1 221125_WJC_METTL3_EV_vs_WT_F01.21432.21432.2 1.22E-10 16/32 R.EIISEMGELGVLGPTIK.G "sp|Q92947|GCDH_HUMAN,tr|K7ES74|K7ES74_HUMAN,tr|K7EKT3|K7EKT3_HUMAN" 3 1784.9594 -1 8804 21432 2 1784.960225 893.487 "Glutaryl-CoA dehydrogenase, mitochondrial OS=Homo sapiens OX=9606 GN=GCDH PE=1 SV=1" 4.25 3888.3 - 336298 - - - 0.4689 - 3.16 0.652 - 682.1 1 2 0 0.0008 17 0 0 0 0.00E+00 0.00E+00 - - - 6.6851 0.9999 221125_WJC_METTL3_EV_vs_WT_F01.21433.21433.2 4.93E-06 14/24 R.VALTGLTVAEYFR[166.11].D "sp|P06576|ATPB_HUMAN,tr|F8W0P7|F8W0P7_HUMAN,tr|H0YH81|H0YH81_HUMAN" 3 1448.7903 1.77 8805 21433 2 1448.791648 725.4024 "ATP synthase subunit beta, mitochondrial OS=Homo sapiens OX=9606 GN=ATP5F1B PE=1 SV=3" 5.97 3888.5 - 336239 - - - 0.9401 - 3.065 0.467 - 743.1 1 2 0 0.0014 13 0 0 0 5.63E+07 3.19E+07 - - - 5.3645 0.9999 221125_WJC_METTL3_EV_vs_WT_F01.21434.21434.2 2.96E-05 15/26 K.VLLLSSPGLEELYR[166.11].C "sp|Q8N163|CCAR2_HUMAN,tr|E5RHJ4|E5RHJ4_HUMAN,tr|H0YB24|H0YB24_HUMAN" 3 1597.8955 -1 8806 21434 2 1597.896516 799.955 Cell cycle and apoptosis regulator protein 2 OS=Homo sapiens OX=9606 GN=CCAR2 PE=1 SV=2 4.53 3888.6 - 333606 - - - 0.649 - 2.803 0.48 - 728.6 1 2 0 0.001 14 0 0 0 0.00E+00 0.00E+00 - - - 5.1724 1 221125_WJC_METTL3_EV_vs_WT_F01.21436.21436.2 1.71E-10 17/32 R.EIISEMGELGVLGPTIK[136.11].G "sp|Q92947|GCDH_HUMAN,tr|K7ES74|K7ES74_HUMAN,tr|K7EKT3|K7EKT3_HUMAN" 3 1792.9736 -1 8808 21436 2 1792.97309 897.4941 "Glutaryl-CoA dehydrogenase, mitochondrial OS=Homo sapiens OX=9606 GN=GCDH PE=1 SV=1" 4.25 3888.9 - 318233 - - - -0.2778 - 3.43 0.642 - 946.9 1 2 0 -0.0005 17 0 0 0 0.00E+00 0.00E+00 - - - 6.813 0.9996 221125_WJC_METTL3_EV_vs_WT_F01.21437.21437.3 1.32E-05 15/72 R.LFVSDGVPGC[160.03]LPVLAAAGR[166.11].A "sp|P56192|SYMC_HUMAN,tr|F8W0S4|F8W0S4_HUMAN,tr|F8W0M7|F8W0M7_HUMAN,tr|F8VPL7|F8VPL7_HUMAN,tr|F5H2V6|F5H2V6_HUMAN,tr|F8VS26|F8VS26_HUMAN,tr|F8VZZ9|F8VZZ9_HUMAN" 7 1908.0167 0.94 8809 21437 3 1908.00889 637.0128 "Methionine--tRNA ligase, cytoplasmic OS=Homo sapiens OX=9606 GN=MARS1 PE=1 SV=2" 5.83 3889 - 317367 - - - -4.0796 - 2.736 0.451 - 168.4 1 2 0 -0.0078 19 0 0 0 1.58E+06 1.68E+06 - - - 6.0388 0.9999 221125_WJC_METTL3_EV_vs_WT_F01.21439.21439.3 0.000212 Nov-44 R.LFPPQWIC[160.03]C[160.03]DIR[166.11].Y sp|Q86U44|MTA70_HUMAN 1 1613.7722 0.01 8810 21439 3 1613.773296 538.9313 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 5.82 3889.2 - 260144 - - - 0.673 - 1.867 0.41 - 115.5 1 2 0 0.0011 12 0 0 0 3.24E+05 2.49E+07 - - - 4.8414 0.9983 221125_WJC_METTL3_EV_vs_WT_F01.21440.21440.2 0.0518 16-Aug K.MVSVLPIFR[166.11].S sp|Q8NBF2|NHLC2_HUMAN 1 1070.6186 -1 8811 21440 2 1070.618993 536.3166 NHL repeat-containing protein 2 OS=Homo sapiens OX=9606 GN=NHLRC2 PE=1 SV=1 9.5 3889.3 - 144479 - - - 0.3736 - 1.167 0.338 - 153.8 1 2 0 0.0004 9 0 0 0 0.00E+00 0.00E+00 - - - 1.9841 0.9995 221125_WJC_METTL3_EV_vs_WT_F01.21441.21441.2 0.0409 14-Aug K.ENLLDFIK.H "sp|P07237|PDIA1_HUMAN,tr|A0A7P0TA97|A0A7P0TA97_HUMAN,tr|A0A7P0T8C0|A0A7P0T8C0_HUMAN,tr|H7BZ94|H7BZ94_HUMAN,tr|A0A7P0TA71|A0A7P0TA71_HUMAN,tr|I3L4M2|I3L4M2_HUMAN,tr|A0A7P0T9D6|A0A7P0T9D6_HUMAN,tr|A0A7P0T9K9|A0A7P0T9K9_HUMAN,tr|H0Y3Z3|H0Y3Z3_HUMAN,tr|A0A7P0Z4S2|A0A7P0Z4S2_HUMAN,tr|A0A7P0TA35|A0A7P0TA35_HUMAN,tr|I3L514|I3L514_HUMAN,tr|A0A7P0TB26|A0A7P0TB26_HUMAN,tr|A0A7P0T9U6|A0A7P0T9U6_HUMAN,tr|I3L0S0|I3L0S0_HUMAN,tr|I3L3P5|I3L3P5_HUMAN,tr|A0A7P0T8J3|A0A7P0T8J3_HUMAN,tr|A0A7P0Z4J0|A0A7P0Z4J0_HUMAN,tr|A0A7P0T8X1|A0A7P0T8X1_HUMAN" 19 990.5386 1.4 8812 21441 2 990.538975 496.2766 Protein disulfide-isomerase OS=Homo sapiens OX=9606 GN=P4HB PE=1 SV=3 4.37 3889.4 - 5.47E+06 - - - 0.3816 - 1.826 0.289 - 233.8 1 2 0 0.0004 8 0 0 0 3.79E+07 2.71E+07 - - - 2.9914 0.9881 221125_WJC_METTL3_EV_vs_WT_F01.21442.21442.2 6.59E-05 18-Sep R.QNLEPLFEQY.L "sp|P48668|K2C6C_HUMAN,sp|P04259|K2C6B_HUMAN,sp|P13647|K2C5_HUMAN,sp|P02538|K2C6A_HUMAN,tr|F8W0C6|F8W0C6_HUMAN" 5 1279.6085 - 8813 21442 2 1279.609362 640.8115 "Keratin, type II cytoskeletal 6C OS=Homo sapiens OX=9606 GN=KRT6C PE=1 SV=3" 3.79 3889.4 - 3.41E+06 - - - 0.6987 - 1.94 0.46 - 261.2 1 1 0 0.0009 10 0 0 0 - - - - - 4.288 1 221125_WJC_METTL3_EV_vs_WT_F01.21445.21445.3 2.01E-06 13/48 R.VALTGLTVAEYFR.D "sp|P06576|ATPB_HUMAN,tr|F8W0P7|F8W0P7_HUMAN,tr|H0YH81|H0YH81_HUMAN" 3 1438.782 1.79 8816 21445 3 1438.78256 480.6013 "ATP synthase subunit beta, mitochondrial OS=Homo sapiens OX=9606 GN=ATP5F1B PE=1 SV=3" 5.97 3889.7 - 877868 - - - 0.3781 - 2.617 0.465 - 267.9 1 2 0 0.0005 13 0 0 0 5.70E+06 3.19E+06 - - - 6.3325 0.9998 221125_WJC_METTL3_EV_vs_WT_F01.21446.21446.2 0.000112 22-Oct R.YFPTQALNFAFK[136.11].D "sp|P12235|ADT1_HUMAN,sp|Q9H0C2|ADT4_HUMAN,sp|P05141|ADT2_HUMAN,sp|P12236|ADT3_HUMAN,tr|V9GYG0|V9GYG0_HUMAN" 5 1453.7485 0.92 8817 21446 2 1453.748889 727.8815 ADP\ATP translocase 1 OS=Homo sapiens OX=9606 GN=SLC25A4 PE=1 SV=4 8.59 3889.8 - 825199 - - - 0.2421 - 1.959 0.431 - 294.1 1 2 0 0.0004 12 0 0 0 1.34E+07 1.46E+07 - - - 3.9935 0.9714 221125_WJC_METTL3_EV_vs_WT_F01.21453.21453.2 0.0245 18-Oct T.NILLVDEIMR[166.11].A "sp|Q92526|TCPW_HUMAN,sp|P40227|TCPZ_HUMAN" 2 1224.6776 -1 8824 21453 2 1224.677474 613.3461 T-complex protein 1 subunit zeta-2 OS=Homo sapiens OX=9606 GN=CCT6B PE=1 SV=5 4.37 3890.6 - 497940 - - - -0.0735 - 1.983 0.282 - 382.8 1 1 0 -0.0001 10 0 0 0 0.00E+00 0.00E+00 - - - 3.0348 0.9976 221125_WJC_METTL3_EV_vs_WT_F01.21454.21454.2 0.00255 16-Jul R.GYPTLLLFR[166.11].G sp|Q8NBS9|TXND5_HUMAN 1 1088.6258 0.32 8825 21454 2 1088.628551 545.3202 Thioredoxin domain-containing protein 5 OS=Homo sapiens OX=9606 GN=TXNDC5 PE=1 SV=2 8.75 3890.8 - 305498 - - - 2.5399 - 1.489 0.337 - 179.2 1 2 0 0.0028 9 0 0 0 5.94E+06 1.87E+07 - - - 2.681 0.9995 221125_WJC_METTL3_EV_vs_WT_F01.21455.21455.2 1.91E-05 20-Nov K.LPDVYGVFQFK.V "sp|P39656|OST48_HUMAN,tr|A0A0C4DGS1|A0A0C4DGS1_HUMAN" 2 1311.6863 3.89 8826 21455 2 1311.689423 656.8504 Dolichyl-diphosphooligosaccharide--protein glycosyltransferase 48 kDa subunit OS=Homo sapiens OX=9606 GN=DDOST PE=1 SV=4 5.83 3890.9 - 290632 - - - 2.3626 - 2.289 0.431 - 368.7 1 2 0 0.0031 11 0 0 0 2.28E+06 5.87E+05 - - - 4.4636 0.9557 221125_WJC_METTL3_EV_vs_WT_F01.21456.21456.2 0.000269 16-Sep L.LFMDLLDER.T "sp|Q969X6|UTP4_HUMAN,tr|H3BRM8|H3BRM8_HUMAN,tr|H3BSH7|H3BSH7_HUMAN,tr|A0A0J9YXV4|A0A0J9YXV4_HUMAN,tr|A0A0J9YWM9|A0A0J9YWM9_HUMAN" 5 1150.5692 0.06 8827 21456 2 1150.565909 576.2919 U3 small nucleolar RNA-associated protein 4 homolog OS=Homo sapiens OX=9606 GN=UTP4 PE=1 SV=1 4.03 3891 - 234312 - - - -2.9003 - 1.816 0.463 - 261.3 1 1 0 -0.0033 9 0 0 0 1.06E+06 1.85E+07 - - - 4.1858 0.9876 221125_WJC_METTL3_EV_vs_WT_F01.21457.21457.3 0.161 Sep-64 R.EIISEMGELGVLGPTIK[136.11].G "sp|Q92947|GCDH_HUMAN,tr|K7ES74|K7ES74_HUMAN,tr|K7EKT3|K7EKT3_HUMAN" 3 1792.9736 1.22 8828 21457 3 1792.972874 598.6651 "Glutaryl-CoA dehydrogenase, mitochondrial OS=Homo sapiens OX=9606 GN=GCDH PE=1 SV=1" 4.25 3891.2 - 223562 - - - -0.3982 - 1.731 0.157 - 76.3 1 2 0 -0.0007 17 0 0 0 9.94E+05 8.15E+05 - - - 1.6764 1 221125_WJC_METTL3_EV_vs_WT_F01.21460.21460.2 0.000194 15/24 R.VALTGLTVAEYFR.D "sp|P06576|ATPB_HUMAN,tr|F8W0P7|F8W0P7_HUMAN,tr|H0YH81|H0YH81_HUMAN" 3 1438.782 1.77 8830 21460 2 1438.782487 720.3983 "ATP synthase subunit beta, mitochondrial OS=Homo sapiens OX=9606 GN=ATP5F1B PE=1 SV=3" 5.97 3891.5 - 2.12E+07 - - - 0.3274 - 3.156 0.538 - 1030.1 1 2 0 0.0005 13 0 0 0 5.63E+07 3.19E+07 - - - 5.9642 0.9999 221125_WJC_METTL3_EV_vs_WT_F01.21463.21463.2 0.00119 16-Nov R.IDLAVLLGK.T "sp|Q14157|UBP2L_HUMAN,tr|F8W726|F8W726_HUMAN,tr|Q5VU77|Q5VU77_HUMAN" 3 940.5957 2.16 8833 21463 2 940.595667 471.3051 Ubiquitin-associated protein 2-like OS=Homo sapiens OX=9606 GN=UBAP2L PE=1 SV=2 5.84 3891.8 - 3.90E+06 - - - -0.0542 - 2.311 0.484 - 330.1 1 2 0 -0.0001 9 0 0 0 2.85E+08 1.32E+08 - - - 5.0393 0.9999 221125_WJC_METTL3_EV_vs_WT_F01.21465.21465.2 0.00779 13/16 R.IDLAVLLGK[136.11].T "sp|Q14157|UBP2L_HUMAN,tr|F8W726|F8W726_HUMAN,tr|Q5VU77|Q5VU77_HUMAN" 3 948.6099 2.16 8835 21465 2 948.609734 475.3122 Ubiquitin-associated protein 2-like OS=Homo sapiens OX=9606 GN=UBAP2L PE=1 SV=2 5.84 3891.9 - 2.31E+06 - - - -0.194 - 2.477 0.503 - 454.6 1 2 0 -0.0002 9 0 0 0 2.85E+08 1.32E+08 - - - 5.3802 0.9999 221125_WJC_METTL3_EV_vs_WT_F01.21466.21466.2 1.66E-06 28-Dec K.IVFVPGC[160.03]SIPLTIVK[136.11].S sp|P54136|SYRC_HUMAN 1 1649.967 0.83 8836 21466 2 1649.966585 825.9908 "Arginine--tRNA ligase, cytoplasmic OS=Homo sapiens OX=9606 GN=RARS1 PE=1 SV=2" 8.22 3892 - 1.86E+06 - - - -0.2436 - 2.17 0.543 - 333.1 1 2 0 -0.0004 15 0 0 0 4.71E+06 5.70E+06 - - - 4.9562 0.9999 221125_WJC_METTL3_EV_vs_WT_F01.21467.21467.2 1.87E-06 28-Dec K.IVFVPGC[160.03]SIPLTIVK.S sp|P54136|SYRC_HUMAN 1 1641.9528 0.83 8837 21467 2 1641.951906 821.9837 "Arginine--tRNA ligase, cytoplasmic OS=Homo sapiens OX=9606 GN=RARS1 PE=1 SV=2" 8.22 3892.1 - 1.59E+06 - - - -0.5366 - 2.31 0.604 - 331.7 1 2 0 -0.0009 15 0 0 0 4.71E+06 5.70E+06 - - - 5.5603 0.9998 221125_WJC_METTL3_EV_vs_WT_F01.21468.21468.3 0.00038 Nov-48 R.VALTGLTVAEYFR[166.11].D "sp|P06576|ATPB_HUMAN,tr|F8W0P7|F8W0P7_HUMAN,tr|H0YH81|H0YH81_HUMAN" 3 1448.7903 -1 8838 21468 3 1448.790149 483.9374 "ATP synthase subunit beta, mitochondrial OS=Homo sapiens OX=9606 GN=ATP5F1B PE=1 SV=3" 5.97 3892.1 - 1.55E+06 - - - -0.0946 - 1.95 0.371 - 147.1 1 2 0 -0.0001 13 0 0 0 0.00E+00 0.00E+00 - - - 4.4869 0.9999 221125_WJC_METTL3_EV_vs_WT_F01.21470.21470.3 0.000149 14/56 K.IVFVPGC[160.03]SIPLTIVK[136.11].S sp|P54136|SYRC_HUMAN 1 1649.967 1.01 8840 21470 3 1649.969483 550.9963 "Arginine--tRNA ligase, cytoplasmic OS=Homo sapiens OX=9606 GN=RARS1 PE=1 SV=2" 8.22 3892.3 - 898011 - - - 1.5128 - 2.154 0.424 - 212.8 1 2 0 0.0025 15 0 0 0 2.24E+06 2.22E+06 - - - 5.2687 0.9966 221125_WJC_METTL3_EV_vs_WT_F01.21471.21471.2 0.103 22-Sep K.VVYTSLQWASLQ.- "sp|Q9BSV6|SEN34_HUMAN,tr|A0A590UJ73|A0A590UJ73_HUMAN" 2 1393.7242 - 8841 21471 2 1393.723369 697.8694 tRNA-splicing endonuclease subunit Sen34 OS=Homo sapiens OX=9606 GN=TSEN34 PE=1 SV=1 5.49 3892.5 - 779432 - - - -0.5718 - 1.412 0.199 - 133.9 1 2 0 -0.0008 12 0 0 0 - - - - - 1.4183 0.9921 221125_WJC_METTL3_EV_vs_WT_F01.21473.21473.2 3.11E-06 26-Oct N.SLTYSPFGDSPLFR[166.11].N "sp|P52948|NUP98_HUMAN,tr|A0A3B3ITD8|A0A3B3ITD8_HUMAN,tr|H0YEN4|H0YEN4_HUMAN,tr|H0YCR0|H0YCR0_HUMAN" 4 1595.7859 -1 8843 21473 2 1595.784793 798.9002 Nuclear pore complex protein Nup98-Nup96 OS=Homo sapiens OX=9606 GN=NUP98 PE=1 SV=4 5.55 3892.7 - 573782 - - - -0.7119 - 2.198 0.517 - 288 1 1 0 -0.0011 14 0 0 0 0.00E+00 0.00E+00 - - - 4.8355 0.9992 221125_WJC_METTL3_EV_vs_WT_F01.21474.21474.2 0.00371 16-Aug K.DLPPILLVR.G sp|P55011|S12A2_HUMAN 1 1034.6488 23.57 8844 21474 2 1034.64959 518.3317 Solute carrier family 12 member 2 OS=Homo sapiens OX=9606 GN=SLC12A2 PE=1 SV=1 5.84 3892.8 - 508978 - - - 0.7471 - 1.328 0.384 - 204.8 1 2 0 0.0008 9 0 0 0 2.86E+06 1.21E+05 - - - 2.6977 0.9988 221125_WJC_METTL3_EV_vs_WT_F01.21477.21477.2 0.0317 16-Jul R.GYPTLLLFR.G sp|Q8NBS9|TXND5_HUMAN 1 1078.6175 0.32 8847 21477 2 1078.617458 540.316 Thioredoxin domain-containing protein 5 OS=Homo sapiens OX=9606 GN=TXNDC5 PE=1 SV=2 8.75 3893.2 - 476827 - - - -0.0538 - 1.518 0.267 - 142.2 1 2 0 -0.0001 9 0 0 0 5.41E+06 1.72E+07 - - - 2.2206 0.9334 221125_WJC_METTL3_EV_vs_WT_F01.21487.21487.2 0.0026 18-Oct N.IYLIPDIDLK.L sp|Q92922|SMRC1_HUMAN 1 1201.6958 2.97 8856 21487 2 1201.693786 601.8552 SWI\SNF complex subunit SMARCC1 OS=Homo sapiens OX=9606 GN=SMARCC1 PE=1 SV=3 4.21 3894.1 - 1.03E+06 - - - -1.6976 - 1.686 0.302 - 332.1 1 1 0 -0.002 10 0 0 0 2.30E+06 7.73E+05 - - - 2.729 0.9999 221125_WJC_METTL3_EV_vs_WT_F01.21494.21494.2 4.07E-07 13/26 R.LLVPTQYVGAIIGK.E sp|Q9NZI8|IF2B1_HUMAN 1 1470.881 1.53 8863 21494 2 1470.880897 736.4478 Insulin-like growth factor 2 mRNA-binding protein 1 OS=Homo sapiens OX=9606 GN=IGF2BP1 PE=1 SV=2 8.59 3895 - 404634 - - - -0.0707 - 2.648 0.55 - 390 1 2 0 -0.0001 14 0 0 0 2.29E+08 1.50E+08 - - - 5.547 1 221125_WJC_METTL3_EV_vs_WT_F01.21495.21495.2 1.41E-06 15/26 R.LLVPTQYVGAIIGK[136.11].E sp|Q9NZI8|IF2B1_HUMAN 1 1478.8952 1.53 8864 21495 2 1478.889387 740.4549 Insulin-like growth factor 2 mRNA-binding protein 1 OS=Homo sapiens OX=9606 GN=IGF2BP1 PE=1 SV=2 8.59 3895.1 - 364595 - - - -3.9313 - 2.726 0.601 - 576.5 1 2 0 -0.0058 14 0 0 0 2.29E+08 1.50E+08 - - - 5.9947 0.8672 221125_WJC_METTL3_EV_vs_WT_F01.21497.21497.2 1.28 22-Jun R.FSPIPFPPLSYK[136.11].H "sp|Q6P2Q9|PRP8_HUMAN,tr|I3L0J9|I3L0J9_HUMAN" 2 1399.7631 2.48 8866 21497 2 1399.75993 700.8888 Pre-mRNA-processing-splicing factor 8 OS=Homo sapiens OX=9606 GN=PRPF8 PE=1 SV=2 8.59 3895.4 - 266651 - - - -2.2825 - 0.893 0.103 - 92.6 1 2 0 -0.0032 12 0 0 0 6.71E+06 2.70E+06 - - - -0.497 0.9862 221125_WJC_METTL3_EV_vs_WT_F01.21501.21501.2 2.54E-05 13/20 Q.AFADALLIIPK[136.11].V "sp|Q92526|TCPW_HUMAN,sp|P40227|TCPZ_HUMAN" 2 1178.7154 0.47 8868 21501 2 1178.713212 590.365 T-complex protein 1 subunit zeta-2 OS=Homo sapiens OX=9606 GN=CCT6B PE=1 SV=5 5.88 3895.9 - 3.23E+06 - - - -1.8953 - 2.329 0.488 - 420.8 1 1 0 -0.0022 11 0 0 0 9.57E+06 2.02E+07 - - - 4.9318 0.9948 221125_WJC_METTL3_EV_vs_WT_F01.21505.21505.2 8.16E-06 14/20 Q.AFADALLIIPK.V "sp|Q92526|TCPW_HUMAN,sp|P40227|TCPZ_HUMAN" 2 1170.7012 0.47 8872 21505 2 1170.701203 586.3579 T-complex protein 1 subunit zeta-2 OS=Homo sapiens OX=9606 GN=CCT6B PE=1 SV=5 5.88 3896.3 - 1.74E+06 - - - -0.0367 - 2.37 0.562 - 532.9 1 1 0 0 11 0 0 0 9.57E+06 2.02E+07 - - - 5.5262 0.9991 221125_WJC_METTL3_EV_vs_WT_F01.21512.21512.2 0.0022 14-Aug R.AAFLNFFR.D sp|Q5JTZ9|SYAM_HUMAN 1 984.5181 1.28 8879 21512 2 984.516349 493.2663 "Alanine--tRNA ligase, mitochondrial OS=Homo sapiens OX=9606 GN=AARS2 PE=1 SV=1" 9.79 3897 - 690461 - - - -1.8161 - 1.633 0.347 - 220 1 2 0 -0.0018 8 0 0 0 2.99E+06 2.33E+06 - - - 3.0825 0.9992 221125_WJC_METTL3_EV_vs_WT_F01.21516.21516.2 5.71E-05 24-Nov K.ELAGALAYIMDNK[136.11].L "sp|Q14527|HLTF_HUMAN,tr|A0A0C4DGA6|A0A0C4DGA6_HUMAN" 2 1415.721 -1 8883 21516 2 1415.716165 708.8678 Helicase-like transcription factor OS=Homo sapiens OX=9606 GN=HLTF PE=1 SV=2 4.37 3897.5 - 320116 - - - -3.4166 - 2.609 0.447 - 367.4 1 2 0 -0.0048 13 0 0 0 0.00E+00 0.00E+00 - - - 4.8022 0.9999 221125_WJC_METTL3_EV_vs_WT_F01.21517.21517.2 1.18E-05 26-Nov R.GPVYIGELPQDFLR.L "sp|Q9H0E2|TOLIP_HUMAN,tr|E9PNS3|E9PNS3_HUMAN,tr|F2Z2Y8|F2Z2Y8_HUMAN" 3 1602.8406 -1 8884 21517 2 1602.840448 802.4276 Toll-interacting protein OS=Homo sapiens OX=9606 GN=TOLLIP PE=1 SV=1 4.37 3897.7 - 175886 - - - -0.0905 - 2.22 0.496 - 416.1 1 2 0 -0.0001 14 0 0 0 0.00E+00 0.00E+00 - - - 4.7057 0.9999 221125_WJC_METTL3_EV_vs_WT_F01.21521.21521.3 0.000101 Oct-52 R.LLVPTQYVGAIIGK.E sp|Q9NZI8|IF2B1_HUMAN 1 1470.881 1.47 8887 21521 3 1470.879991 491.3009 Insulin-like growth factor 2 mRNA-binding protein 1 OS=Homo sapiens OX=9606 GN=IGF2BP1 PE=1 SV=2 8.59 3898.1 - 2.58E+06 - - - -0.6867 - 2.124 0.428 - 117.8 1 2 0 -0.001 14 0 0 0 3.75E+07 2.56E+07 - - - 5.3134 1 221125_WJC_METTL3_EV_vs_WT_F01.21522.21522.3 2.23E-06 15/52 R.LLVPTQYVGAIIGK[136.11].E sp|Q9NZI8|IF2B1_HUMAN 1 1478.8952 1.47 8888 21522 3 1478.892151 493.9723 Insulin-like growth factor 2 mRNA-binding protein 1 OS=Homo sapiens OX=9606 GN=IGF2BP1 PE=1 SV=2 8.59 3898.2 - 2.00E+06 - - - -2.0624 - 2.671 0.536 - 298.8 1 2 0 -0.0031 14 0 0 0 3.75E+07 2.56E+07 - - - 7.1259 0.9996 221125_WJC_METTL3_EV_vs_WT_F01.21528.21528.2 0.054 14-Aug R.AAFLNFFR[166.11].D sp|Q5JTZ9|SYAM_HUMAN 1 994.5264 -1 8894 21528 2 994.525536 498.2705 "Alanine--tRNA ligase, mitochondrial OS=Homo sapiens OX=9606 GN=AARS2 PE=1 SV=1" 9.79 3898.9 - 633308 - - - -0.8758 - 1.699 0.382 - 221.9 1 2 0 -0.0009 8 0 0 0 0.00E+00 0.00E+00 - - - 3.4608 0.9997 221125_WJC_METTL3_EV_vs_WT_F01.21535.21535.2 0.00438 16-Sep R.YLDVSILGK[136.11].F sp|Q86U44|MTA70_HUMAN 1 1014.5841 0.19 8900 21535 2 1014.584818 508.2993 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 5.83 3899.8 - 1.54E+06 - - - 0.7097 - 1.756 0.425 - 195.9 1 2 0 0.0007 9 0 0 0 3.29E+06 1.75E+07 - - - 3.8087 0.9997 221125_WJC_METTL3_EV_vs_WT_F01.21537.21537.2 1.63E-05 22-Nov K.WLAPDGLIFPDR.A "sp|Q99873|ANM1_HUMAN,tr|E9PQ98|E9PQ98_HUMAN,tr|E9PKG1|E9PKG1_HUMAN,tr|E9PNR9|E9PNR9_HUMAN,tr|H0YDE4|H0YDE4_HUMAN,tr|E9PIX6|E9PIX6_HUMAN" 6 1398.7296 2.26 8902 21537 2 1398.726141 700.3721 Protein arginine N-methyltransferase 1 OS=Homo sapiens OX=9606 GN=PRMT1 PE=1 SV=3 4.21 3900 - 2.31E+06 - - - -2.4629 - 2.57 0.524 - 431.8 1 2 0 -0.0034 12 0 0 0 7.72E+07 3.42E+07 - - - 5.3938 0.9955 221125_WJC_METTL3_EV_vs_WT_F01.21539.21539.2 0.000834 18-Sep R.GLIPVFALGR[166.11].A "sp|Q9UKF6|CPSF3_HUMAN,tr|G5E9W3|G5E9W3_HUMAN" 2 1051.6418 1.03 8904 21539 2 1051.637024 526.8282 Cleavage and polyadenylation specificity factor subunit 3 OS=Homo sapiens OX=9606 GN=CPSF3 PE=1 SV=1 9.75 3900.2 - 1.04E+06 - - - -4.5139 - 1.75 0.385 - 201.6 1 2 0 -0.0047 10 0 0 0 3.81E+06 3.72E+06 - - - 3.4452 0.9998 221125_WJC_METTL3_EV_vs_WT_F01.21540.21540.2 8.31E-06 26-Dec K.TYVLNPLAPEFIPR[166.11].A "sp|P42694|HELZ_HUMAN,tr|J3QS41|J3QS41_HUMAN" 2 1638.9009 2.56 8905 21540 2 1638.898469 820.4577 Probable helicase with zinc finger domain OS=Homo sapiens OX=9606 GN=HELZ PE=1 SV=2 5.66 3900.3 - 847005 - - - -1.4827 - 2.477 0.468 - 387.9 1 2 0 -0.0024 14 0 0 0 1.82E+07 7.11E+06 - - - 4.7731 0.9997 221125_WJC_METTL3_EV_vs_WT_F01.21544.21544.2 0.000423 24-Nov R.NLATTVTEEILEK.S "sp|O43390|HNRPR_HUMAN,tr|B4DT28|B4DT28_HUMAN,tr|A0A6Q8PHG0|A0A6Q8PHG0_HUMAN,tr|A0A6Q8PH31|A0A6Q8PH31_HUMAN,tr|A0A6Q8PH35|A0A6Q8PH35_HUMAN" 5 1459.777 1.16 8909 21544 2 1459.774395 730.8958 Heterogeneous nuclear ribonucleoprotein R OS=Homo sapiens OX=9606 GN=HNRNPR PE=1 SV=1 4.25 3900.8 - 495495 - - - -1.7777 - 2.341 0.422 - 287.3 1 2 0 -0.0026 13 0 0 0 5.67E+06 4.88E+06 - - - 4.3401 0.9995 221125_WJC_METTL3_EV_vs_WT_F01.21545.21545.2 7.02E-06 28-Dec R.IFLLTNNNLLLADQK[136.11].S "sp|O43795|MYO1B_HUMAN,tr|E9PDF6|E9PDF6_HUMAN,tr|H7C2Y7|H7C2Y7_HUMAN" 3 1736.9916 -1 8910 21545 2 1736.985929 869.5031 Unconventional myosin-Ib OS=Homo sapiens OX=9606 GN=MYO1B PE=1 SV=3 5.84 3900.9 - 479924 - - - -3.2769 - 2.642 0.571 - 350.9 1 2 0 -0.0057 15 0 0 0 0.00E+00 0.00E+00 - - - 5.6452 0.9995 221125_WJC_METTL3_EV_vs_WT_F01.21551.21551.2 0.00239 14-Aug R.GFGFVLFK.E "sp|Q14103|HNRPD_HUMAN,sp|O14979|HNRDL_HUMAN,tr|H0Y8G5|H0Y8G5_HUMAN,tr|A0A087WUK2|A0A087WUK2_HUMAN,tr|D6RF44|D6RF44_HUMAN,tr|D6RBQ9|D6RBQ9_HUMAN,tr|D6RAF8|D6RAF8_HUMAN,tr|H0YA96|H0YA96_HUMAN" 8 913.5062 1.26 8914 21551 2 913.504572 457.7604 Heterogeneous nuclear ribonucleoprotein D0 OS=Homo sapiens OX=9606 GN=HNRNPD PE=1 SV=1 8.75 3901.8 - 5.12E+06 - - - -1.7548 - 1.503 0.447 - 209.5 1 2 0 -0.0016 8 0 0 0 3.89E+08 3.09E+08 - - - 3.5709 0.9997 221125_WJC_METTL3_EV_vs_WT_F01.21552.21552.2 0.00029 20-Nov R.SVVTVIDVFYK.Y sp|Q5D862|FILA2_HUMAN 1 1268.7016 77.59 8915 21552 2 1268.699696 635.3581 Filaggrin-2 OS=Homo sapiens OX=9606 GN=FLG2 PE=1 SV=1 5.55 3901.8 - 3.19E+06 - - - -1.5323 - 2.186 0.417 - 352.7 1 2 0 -0.0019 11 0 0 0 9.52E+07 1.23E+06 - - - 4.236 0.9999 221125_WJC_METTL3_EV_vs_WT_F01.21553.21553.2 1.95E-06 22-Nov K.WLAPDGLIFPDR[166.11].A "sp|Q99873|ANM1_HUMAN,tr|E9PQ98|E9PQ98_HUMAN,tr|E9PKG1|E9PKG1_HUMAN,tr|E9PNR9|E9PNR9_HUMAN,tr|H0YDE4|H0YDE4_HUMAN,tr|E9PIX6|E9PIX6_HUMAN" 6 1408.7379 2.26 8916 21553 2 1408.736752 705.3762 Protein arginine N-methyltransferase 1 OS=Homo sapiens OX=9606 GN=PRMT1 PE=1 SV=3 4.21 3901.9 - 3.70E+06 - - - -0.7837 - 2.64 0.537 - 412.3 1 2 0 -0.0011 12 0 0 0 7.72E+07 3.42E+07 - - - 5.5612 0.998 221125_WJC_METTL3_EV_vs_WT_F01.21556.21556.2 0.000705 18-Nov K.AWLLSMIQSK[136.11].C "sp|Q9UBU9|NXF1_HUMAN,tr|E9PLA7|E9PLA7_HUMAN,tr|E9PIN3|E9PIN3_HUMAN" 3 1183.6515 1.15 8919 21556 2 1183.653147 592.833 Nuclear RNA export factor 1 OS=Homo sapiens OX=9606 GN=NXF1 PE=1 SV=1 8.8 3902.2 - 1.06E+06 - - - 1.4202 - 1.801 0.206 - 387.9 1 2 0 0.0017 10 0 0 0 7.28E+06 6.32E+06 - - - 2.2042 0.9812 221125_WJC_METTL3_EV_vs_WT_F01.21557.21557.2 0.000324 18-Sep K.FLDVLELAEK.F "sp|Q9UPN3|MACF1_HUMAN,tr|A0A804HL78|A0A804HL78_HUMAN,tr|H3BQK9|H3BQK9_HUMAN,tr|A0A7P0MQR8|A0A7P0MQR8_HUMAN,tr|H0Y390|H0Y390_HUMAN,tr|H3BPE1|H3BPE1_HUMAN,tr|A0A590UJG2|A0A590UJG2_HUMAN" 7 1175.6438 1.15 8920 21557 2 1175.639597 588.8292 "Microtubule-actin cross-linking factor 1, isoforms 1\2\3\5 OS=Homo sapiens OX=9606 GN=MACF1 PE=1 SV=4" 4.14 3902.3 - 1.05E+06 - - - -3.5674 - 1.913 0.11 - 195 2 2 0 -0.0042 10 0 0 0 6.96E+06 6.05E+06 - - - 1.5283 0.9996 221125_WJC_METTL3_EV_vs_WT_F01.21558.21558.2 0.000337 28-Nov K.AVASLPPEQMFELMK.Q "sp|P33240|CSTF2_HUMAN,sp|Q9H0L4|CSTFT_HUMAN,tr|A0A0A0MT56|A0A0A0MT56_HUMAN,tr|E9PID8|E9PID8_HUMAN,tr|E7EWR4|E7EWR4_HUMAN" 5 1689.847 2.92 8921 21558 2 1689.844812 845.9308 Cleavage stimulation factor subunit 2 OS=Homo sapiens OX=9606 GN=CSTF2 PE=1 SV=1 4.53 3902.4 - 1.02E+06 - - - -1.2954 - 1.859 0.401 - 280 1 2 0 -0.0022 15 0 0 0 7.64E+06 2.62E+06 - - - 3.5265 0.9997 221125_WJC_METTL3_EV_vs_WT_F01.21559.21559.2 0.000285 13/26 K.TALALAIAQELGSK[136.11].V "sp|Q9Y265|RUVB1_HUMAN,tr|E7ETR0|E7ETR0_HUMAN" 2 1392.8068 0.74 8922 21559 2 1392.809986 697.4107 RuvB-like 1 OS=Homo sapiens OX=9606 GN=RUVBL1 PE=1 SV=1 5.66 3902.5 - 855167 - - - 2.3018 - 2.659 0.501 - 327.7 1 2 0 0.0032 14 0 0 0 3.55E+06 4.79E+06 - - - 5.1945 0.9999 221125_WJC_METTL3_EV_vs_WT_F01.21560.21560.2 1.90E-06 22-Oct R.LFPPQWIC[160.03]C[160.03]DIR[166.11].Y sp|Q86U44|MTA70_HUMAN 1 1613.7722 0.02 8923 21560 2 1613.7708 807.8934 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 5.82 3902.6 - 769633 - - - -0.8737 - 2.056 0.56 - 280.9 1 2 0 -0.0014 12 0 0 0 3.95E+06 2.23E+08 - - - 5.0732 1 221125_WJC_METTL3_EV_vs_WT_F01.21562.21562.2 7.56E-07 17/26 K.TALALAIAQELGSK.V "sp|Q9Y265|RUVB1_HUMAN,tr|E7ETR0|E7ETR0_HUMAN" 2 1384.7926 0.74 8925 21562 2 1384.795841 693.4036 RuvB-like 1 OS=Homo sapiens OX=9606 GN=RUVBL1 PE=1 SV=1 5.66 3902.9 - 736386 - - - 2.3549 - 3.346 0.564 - 1320 1 2 0 0.0033 14 0 0 0 3.55E+06 4.79E+06 - - - 6.2365 0.7984 221125_WJC_METTL3_EV_vs_WT_F01.21563.21563.2 3.46 18-Jun R.TAPTAALPPR.A "sp|Q6VB84|FX4L3_HUMAN,sp|Q8WXT5|FX4L4_HUMAN,sp|Q5VV16|FX4L5_HUMAN,sp|Q3SYB3|FX4L6_HUMAN" 4 993.5607 10.4 8926 21563 2 993.558522 497.7876 Forkhead box protein D4-like 3 OS=Homo sapiens OX=9606 GN=FOXD4L3 PE=1 SV=2 9.41 3903 - 735559 - - - -2.2223 - 1.14 0.019 - 66.6 7 2 0 -0.0022 10 0 0 0 4.02E+06 3.86E+05 - - - -0.8311 1 221125_WJC_METTL3_EV_vs_WT_F01.21567.21567.2 3.27E-08 30-Nov H.VEDLYVEGLPEGIPFR.R "sp|P78347|GTF2I_HUMAN,tr|A0A494C0Q7|A0A494C0Q7_HUMAN,tr|A0A494C1K3|A0A494C1K3_HUMAN" 3 1831.9356 1.34 8930 21567 2 1831.937901 916.9751 General transcription factor II-I OS=Homo sapiens OX=9606 GN=GTF2I PE=1 SV=2 4 3903.5 - 410795 - - - 1.2473 - 2.558 0.614 - 379.9 1 1 0 0.0023 16 0 0 0 3.77E+06 2.82E+06 - - - 5.8844 0.9979 221125_WJC_METTL3_EV_vs_WT_F01.21568.21568.3 0.00452 Sep-48 R.NLATTVTEEILEK.S "sp|O43390|HNRPR_HUMAN,tr|B4DT28|B4DT28_HUMAN,tr|A0A6Q8PHG0|A0A6Q8PHG0_HUMAN,tr|A0A6Q8PH31|A0A6Q8PH31_HUMAN,tr|A0A6Q8PH35|A0A6Q8PH35_HUMAN" 5 1459.777 6.34 8931 21568 3 1459.774654 487.5996 Heterogeneous nuclear ribonucleoprotein R OS=Homo sapiens OX=9606 GN=HNRNPR PE=1 SV=1 4.25 3903.6 - 364512 - - - -1.6002 - 1.923 0.243 - 134.2 1 2 0 -0.0023 13 0 0 0 1.15E+06 1.82E+05 - - - 3.0214 0.9996 221125_WJC_METTL3_EV_vs_WT_F01.21575.21575.2 0.0061 20-Nov R.LFEFAGYDVLR[166.11].L sp|P54136|SYRC_HUMAN 1 1338.6848 1.07 8937 21575 2 1338.681578 670.3497 "Arginine--tRNA ligase, cytoplasmic OS=Homo sapiens OX=9606 GN=RARS1 PE=1 SV=2" 4.37 3904.4 - 2.11E+06 - - - -2.3755 - 2.343 0.459 - 423 1 2 0 -0.0032 11 0 0 0 8.55E+06 8.00E+06 - - - 4.7335 0.9998 221125_WJC_METTL3_EV_vs_WT_F01.21576.21576.2 0.000873 20-Nov K.VTDLLGGLFSK.T "sp|O43615|TIM44_HUMAN,tr|M0QXU7|M0QXU7_HUMAN" 2 1148.6441 1.07 8938 21576 2 1148.642804 575.3293 Mitochondrial import inner membrane translocase subunit TIM44 OS=Homo sapiens OX=9606 GN=TIMM44 PE=1 SV=2 5.81 3904.5 - 1.87E+06 - - - -1.1501 - 2.441 0.432 - 511.7 1 2 0 -0.0013 11 0 0 0 7.02E+07 6.56E+07 - - - 4.6455 1 221125_WJC_METTL3_EV_vs_WT_F01.21577.21577.2 7.94E-07 19/30 K.LFIGGLSFETTDESLR.S "sp|Q32P51|RA1L2_HUMAN,sp|P09651|ROA1_HUMAN,tr|F8W646|F8W646_HUMAN,tr|F8VZ49|F8VZ49_HUMAN,tr|A0A7I2V3R8|A0A7I2V3R8_HUMAN,tr|F8VTQ5|F8VTQ5_HUMAN,tr|A0A7I2YQ85|A0A7I2YQ85_HUMAN,tr|F8W6I7|F8W6I7_HUMAN,tr|A0A7I2V2L6|A0A7I2V2L6_HUMAN,tr|A0A7I2V3W0|A0A7I2V3W0_HUMAN" 10 1783.8992 1.23 8939 21577 2 1783.896636 892.9569 Heterogeneous nuclear ribonucleoprotein A1-like 2 OS=Homo sapiens OX=9606 GN=HNRNPA1L2 PE=2 SV=2 4.14 3904.6 - 1.74E+06 - - - -1.4541 - 3.415 0.655 - 1259.5 1 2 0 -0.0026 16 0 0 0 1.41E+07 1.15E+07 - - - 6.8975 0.9996 221125_WJC_METTL3_EV_vs_WT_F01.21578.21578.2 0.000248 13/20 R.FLEEFITPIVK[136.11].V "sp|P11388|TOP2A_HUMAN,sp|Q02880|TOP2B_HUMAN,tr|E9PCY5|E9PCY5_HUMAN" 3 1342.7628 1.1 8940 21578 2 1342.758864 672.3887 DNA topoisomerase 2-alpha OS=Homo sapiens OX=9606 GN=TOP2A PE=1 SV=3 4.53 3904.7 - 1.46E+06 - - - -2.9238 - 2.316 0.517 - 524.5 1 2 0 -0.0039 11 0 0 0 9.91E+06 9.04E+06 - - - 5.1303 0.9992 221125_WJC_METTL3_EV_vs_WT_F01.21579.21579.2 0.00282 18-Nov R.VVTDLISLIR[166.11].Q sp|P38432|COIL_HUMAN 1 1137.6997 0.85 8941 21579 2 1137.697745 569.8571 Coilin OS=Homo sapiens OX=9606 GN=COIL PE=1 SV=1 5.81 3904.9 - 1.07E+06 - - - -1.7008 - 1.99 0.289 - 405.9 1 2 0 -0.0019 10 0 0 0 3.74E+06 4.38E+06 - - - 3.0957 0.9968 221125_WJC_METTL3_EV_vs_WT_F01.21582.21582.2 0.00722 28-Nov R.ELALALQEALEPAVR.L sp|Q5RKV6|EXOS6_HUMAN 1 1621.9039 0.8 8944 21582 2 1621.898475 811.9592 Exosome complex component MTR3 OS=Homo sapiens OX=9606 GN=EXOSC6 PE=1 SV=1 4.25 3905.2 - 606333 - - - -3.3584 - 2.365 0.241 - 281.6 1 2 0 -0.0054 15 0 0 0 2.41E+06 3.04E+06 - - - 2.9356 0.8379 221125_WJC_METTL3_EV_vs_WT_F01.21585.21585.2 0.0027 12-Aug G.FGFVLFK.E "sp|Q14103|HNRPD_HUMAN,sp|O14979|HNRDL_HUMAN,tr|H0Y8G5|H0Y8G5_HUMAN,tr|A0A087WUK2|A0A087WUK2_HUMAN,tr|D6RF44|D6RF44_HUMAN,tr|D6RBQ9|D6RBQ9_HUMAN,tr|D6RAF8|D6RAF8_HUMAN,tr|H0YA96|H0YA96_HUMAN" 8 856.4847 1.09 8947 21585 2 856.480682 429.2496 Heterogeneous nuclear ribonucleoprotein D0 OS=Homo sapiens OX=9606 GN=HNRNPD PE=1 SV=1 8.75 3905.6 - 411488 - - - -4.7041 - 1.752 0.436 - 160.3 1 1 0 -0.004 7 0 0 0 3.09E+06 2.83E+06 - - - 4.0368 0.9829 221125_WJC_METTL3_EV_vs_WT_F01.21587.21587.2 4.24E-05 26-Nov Q.GGVLPNIQAVLLPK[136.11].K "sp|P16104|H2AX_HUMAN,sp|Q9BTM1|H2AJ_HUMAN,sp|Q93077|H2A1C_HUMAN,sp|Q99878|H2A1J_HUMAN,sp|Q16777|H2A2C_HUMAN,sp|Q8IUE6|H2A2B_HUMAN,sp|Q96QV6|H2A1A_HUMAN,sp|P04908|H2A1B_HUMAN,sp|P20671|H2A1D_HUMAN,sp|P0C0S8|H2A1_HUMAN,sp|Q6FI13|H2A2A_HUMAN,sp|Q96KK5|H2A1H_HUMAN,sp|Q7L7L0|H2A3_HUMAN,tr|A0A0U1RR32|A0A0U1RR32_HUMAN,tr|A0A0U1RRH7|A0A0U1RRH7_HUMAN,tr|H0YFX9|H0YFX9_HUMAN" 16 1425.8799 1.26 8949 21587 2 1425.878842 713.9472 Histone H2AX OS=Homo sapiens OX=9606 GN=H2AX PE=1 SV=2 8.75 3905.9 - 310956 - - - -0.7322 - 1.824 0.429 - 288.7 1 1 0 -0.001 14 0 0 0 8.38E+06 6.67E+06 - - - 3.7175 0.956 221125_WJC_METTL3_EV_vs_WT_F01.21588.21588.2 0.000505 12-Jun G.FGFVLFK[136.11].E "sp|Q14103|HNRPD_HUMAN,sp|O14979|HNRDL_HUMAN,tr|H0Y8G5|H0Y8G5_HUMAN,tr|A0A087WUK2|A0A087WUK2_HUMAN,tr|D6RF44|D6RF44_HUMAN,tr|D6RBQ9|D6RBQ9_HUMAN,tr|D6RAF8|D6RAF8_HUMAN,tr|H0YA96|H0YA96_HUMAN" 8 864.4989 1.09 8950 21588 2 864.49671 433.2567 Heterogeneous nuclear ribonucleoprotein D0 OS=Homo sapiens OX=9606 GN=HNRNPD PE=1 SV=1 8.75 3906 - 276305 - - - -2.546 - 1.495 0.479 - 78.1 1 1 0 -0.0022 7 0 0 0 3.09E+06 2.83E+06 - - - 3.8524 0.9997 221125_WJC_METTL3_EV_vs_WT_F01.21589.21589.3 0.000132 Sep-40 R.SVVTVIDVFYK.Y sp|Q5D862|FILA2_HUMAN 1 1268.7016 999 8951 21589 3 1268.700026 423.9078 Filaggrin-2 OS=Homo sapiens OX=9606 GN=FLG2 PE=1 SV=1 5.55 3906.2 - 268170 - - - -1.2722 - 1.917 0.367 - 178.3 1 2 0 -0.0016 11 0 0 0 1.24E+06 0.00E+00 - - - 4.4799 0.9998 221125_WJC_METTL3_EV_vs_WT_F01.21593.21593.2 0.000696 13/20 R.IFGLLMGTLQK.F sp|Q9H307|PININ_HUMAN 1 1219.6999 1.51 8953 21593 2 1219.698137 610.8572 Pinin OS=Homo sapiens OX=9606 GN=PNN PE=1 SV=5 8.75 3906.7 - 7.60E+06 - - - -1.4176 - 2.41 0.489 - 576.8 1 2 0 -0.0017 11 0 0 0 5.35E+07 3.55E+07 - - - 5.0318 0.9999 221125_WJC_METTL3_EV_vs_WT_F01.21594.21594.2 1.04E-05 13/20 R.IFGLLMGTLQK[136.11].F sp|Q9H307|PININ_HUMAN 1 1227.7141 1.51 8954 21594 2 1227.712604 614.8643 Pinin OS=Homo sapiens OX=9606 GN=PNN PE=1 SV=5 8.75 3906.8 - 5.48E+06 - - - -1.1908 - 2.434 0.533 - 547.8 1 2 0 -0.0015 11 0 0 0 5.35E+07 3.55E+07 - - - 5.3837 0.9998 221125_WJC_METTL3_EV_vs_WT_F01.21596.21596.2 0.000158 20-Dec K.YPSPFFVFGEK[136.11].L sp|Q08211|DHX9_HUMAN 1 1324.6583 0.97 8956 21596 2 1324.656392 663.3364 ATP-dependent RNA helicase A OS=Homo sapiens OX=9606 GN=DHX9 PE=1 SV=4 6 3906.9 - 2.54E+06 - - - -1.4592 - 2.333 0.502 - 627.2 1 2 0 -0.0019 11 0 0 0 5.22E+07 5.37E+07 - - - 5.0399 0.9991 221125_WJC_METTL3_EV_vs_WT_F01.21598.21598.2 0.00113 20-Oct R.FLEEFITPIVK.V "sp|P11388|TOP2A_HUMAN,sp|Q02880|TOP2B_HUMAN,tr|E9PCY5|E9PCY5_HUMAN" 3 1334.7486 1.1 8958 21598 2 1334.745343 668.3816 DNA topoisomerase 2-alpha OS=Homo sapiens OX=9606 GN=TOP2A PE=1 SV=3 4.53 3907.1 - 1.57E+06 - - - -2.4327 - 2.038 0.355 - 247 1 2 0 -0.0032 11 0 0 0 9.91E+06 9.04E+06 - - - 3.5881 1 221125_WJC_METTL3_EV_vs_WT_F01.21599.21599.2 2.15E-10 17/30 K.LFIGGLSFETTDESLR[166.11].S "sp|Q32P51|RA1L2_HUMAN,sp|P09651|ROA1_HUMAN,tr|F8W646|F8W646_HUMAN,tr|F8VZ49|F8VZ49_HUMAN,tr|A0A7I2V3R8|A0A7I2V3R8_HUMAN,tr|F8VTQ5|F8VTQ5_HUMAN,tr|A0A7I2YQ85|A0A7I2YQ85_HUMAN,tr|F8W6I7|F8W6I7_HUMAN,tr|A0A7I2V2L6|A0A7I2V2L6_HUMAN,tr|A0A7I2V3W0|A0A7I2V3W0_HUMAN" 10 1793.9075 1.23 8959 21599 2 1793.906252 897.961 Heterogeneous nuclear ribonucleoprotein A1-like 2 OS=Homo sapiens OX=9606 GN=HNRNPA1L2 PE=2 SV=2 4.14 3907.2 - 1.39E+06 - - - -0.6957 - 3.216 0.658 - 910.1 1 2 0 -0.0012 16 0 0 0 1.42E+07 1.16E+07 - - - 6.7725 0.9985 221125_WJC_METTL3_EV_vs_WT_F01.21605.21605.2 0.00312 22-Jul R.FSPIPFPPLSYK.H "sp|Q6P2Q9|PRP8_HUMAN,tr|I3L0J9|I3L0J9_HUMAN" 2 1391.7489 5.32 8965 21605 2 1391.747194 696.8817 Pre-mRNA-processing-splicing factor 8 OS=Homo sapiens OX=9606 GN=PRPF8 PE=1 SV=2 8.59 3908 - 668377 - - - -1.2438 - 1.355 0.332 - 113.7 1 2 0 -0.0017 12 0 0 0 5.27E+06 9.89E+05 - - - 2.292 0.9996 221125_WJC_METTL3_EV_vs_WT_F01.21606.21606.2 0.000221 20-Dec R.TPGGVFLNLLK[136.11].N sp|Q9H814|PHAX_HUMAN 1 1165.695 0.2 8966 21606 2 1165.695473 583.8548 Phosphorylated adapter RNA export protein OS=Homo sapiens OX=9606 GN=PHAX PE=1 SV=1 8.41 3908.1 - 634660 - - - 0.3672 - 1.787 0.38 - 359.1 1 2 0 0.0004 11 0 0 0 1.01E+06 5.12E+06 - - - 3.418 0.9995 221125_WJC_METTL3_EV_vs_WT_F01.21609.21609.2 0.0277 20-Dec K.VTDLLGGLFSK[136.11].T "sp|O43615|TIM44_HUMAN,tr|M0QXU7|M0QXU7_HUMAN" 2 1156.6583 1.07 8968 21609 2 1156.655294 579.3364 Mitochondrial import inner membrane translocase subunit TIM44 OS=Homo sapiens OX=9606 GN=TIMM44 PE=1 SV=2 5.81 3908.5 - 1.67E+07 - - - -2.6205 - 2.615 0.373 - 727.2 1 2 0 -0.003 11 0 0 0 7.02E+07 6.56E+07 - - - 4.3955 0.9999 221125_WJC_METTL3_EV_vs_WT_F01.21613.21613.2 1.48E-05 20-Nov K.YPSPFFVFGEK.L sp|Q08211|DHX9_HUMAN 1 1316.6441 0.97 8971 21613 2 1316.644188 659.3293 ATP-dependent RNA helicase A OS=Homo sapiens OX=9606 GN=DHX9 PE=1 SV=4 6 3908.8 - 3.23E+06 - - - 0.0478 - 2.205 0.559 - 437.6 1 2 0 0.0001 11 0 0 0 5.22E+07 5.37E+07 - - - 5.3089 0.9998 221125_WJC_METTL3_EV_vs_WT_F01.21614.21614.2 4.13E-08 22-Dec R.FSTFFDDAPVFR.L "sp|O60231|DHX16_HUMAN,tr|A0A140T947|A0A140T947_HUMAN,tr|A0A140T9T4|A0A140T9T4_HUMAN,tr|Q5SQH5|Q5SQH5_HUMAN" 4 1447.6772 1.49 8972 21614 2 1447.674464 724.8459 Pre-mRNA-splicing factor ATP-dependent RNA helicase DHX16 OS=Homo sapiens OX=9606 GN=DHX16 PE=1 SV=2 4.21 3908.9 - 1.48E+06 - - - -1.901 - 2.218 0.603 - 495.5 1 2 0 -0.0028 12 0 0 0 1.29E+07 8.69E+06 - - - 5.5899 0.9999 221125_WJC_METTL3_EV_vs_WT_F01.21615.21615.2 1.39E-06 22-Nov R.FSTFFDDAPVFR[166.11].L "sp|O60231|DHX16_HUMAN,tr|A0A140T947|A0A140T947_HUMAN,tr|A0A140T9T4|A0A140T9T4_HUMAN,tr|Q5SQH5|Q5SQH5_HUMAN" 4 1457.6855 1.46 8973 21615 2 1457.684937 729.85 Pre-mRNA-splicing factor ATP-dependent RNA helicase DHX16 OS=Homo sapiens OX=9606 GN=DHX16 PE=1 SV=2 4.21 3909 - 921048 - - - -0.3766 - 2.241 0.592 - 347.5 1 2 0 -0.0006 12 0 0 0 1.29E+07 8.88E+06 - - - 5.5365 0.9998 221125_WJC_METTL3_EV_vs_WT_F01.21616.21616.2 4.09E-05 18-Oct R.SIFC[160.03]PLMSFR.Q "sp|Q9H1Z4|WDR13_HUMAN,tr|A0A087X091|A0A087X091_HUMAN" 2 1256.6046 1.99 8974 21616 2 1256.605818 629.3096 WD repeat-containing protein 13 OS=Homo sapiens OX=9606 GN=WDR13 PE=1 SV=2 7.96 3909.1 - 636354 - - - 0.9804 - 2.051 0.44 - 382.9 1 2 0 0.0012 10 0 0 0 3.19E+06 1.61E+06 - - - 4.2955 0.9953 221125_WJC_METTL3_EV_vs_WT_F01.21617.21617.2 0.0929 14-Jun K.VPNLSQFV.- "sp|P59780|AP3S2_HUMAN,tr|H0YLI7|H0YLI7_HUMAN,tr|A0A0A6YYH1|A0A0A6YYH1_HUMAN" 3 902.4862 - 8975 21617 2 902.484561 452.2504 AP-3 complex subunit sigma-2 OS=Homo sapiens OX=9606 GN=AP3S2 PE=2 SV=1 5.49 3909.3 - 605057 - - - -1.7806 - 1.296 0.241 - 84.2 1 2 0 -0.0016 8 0 0 0 - - - - - 1.6025 0.9939 221125_WJC_METTL3_EV_vs_WT_F01.21619.21619.2 1.07 12-Jun K.ELFSFFR[166.11].D "sp|Q92576|PHF3_HUMAN,tr|E7ER40|E7ER40_HUMAN,tr|E7EVH3|E7EVH3_HUMAN" 3 954.4839 0.81 8977 21619 2 954.483703 478.2492 PHD finger protein 3 OS=Homo sapiens OX=9606 GN=PHF3 PE=1 SV=3 6.1 3909.5 - 528512 - - - -0.1781 - 1.35 0.13 - 151.8 1 2 0 -0.0002 7 0 0 0 3.07E+06 3.79E+06 - - - 0.952 0.9811 221125_WJC_METTL3_EV_vs_WT_F01.21620.21620.2 0.355 20-Jul K.EAVGDLLDAFK[136.11].E "sp|Q04637|IF4G1_HUMAN,tr|C9J2Z7|C9J2Z7_HUMAN,tr|E7EUU4|E7EUU4_HUMAN,tr|E9PGM1|E9PGM1_HUMAN,tr|C9J6B6|C9J6B6_HUMAN,tr|E7EX73|E7EX73_HUMAN,tr|C9K073|C9K073_HUMAN,tr|A0A7I2Y1C3|A0A7I2Y1C3_HUMAN,tr|C9JF13|C9JF13_HUMAN,tr|A0A6Q8PFB2|A0A6Q8PFB2_HUMAN" 10 1184.6169 0.98 8978 21620 2 1184.618493 593.3157 Eukaryotic translation initiation factor 4 gamma 1 OS=Homo sapiens OX=9606 GN=EIF4G1 PE=1 SV=4 4.03 3909.7 - 359426 - - - 1.3836 - 1.151 0.147 - 83.7 1 2 0 0.0016 11 0 0 0 1.99E+06 2.03E+06 - - - 0.5067 0.9886 221125_WJC_METTL3_EV_vs_WT_F01.21625.21625.3 0.185 Aug-40 R.IFGLLMGTLQK.F sp|Q9H307|PININ_HUMAN 1 1219.6999 1.07 8983 21625 3 1219.698181 407.5739 Pinin OS=Homo sapiens OX=9606 GN=PNN PE=1 SV=5 8.75 3910.3 - 204583 - - - -1.3815 - 1.431 0.205 - 80.4 1 2 0 -0.0017 11 0 0 0 8.37E+05 7.80E+05 - - - 1.8432 0.9998 221125_WJC_METTL3_EV_vs_WT_F01.21632.21632.2 0.000277 14-Jul R.GFGFVLFK[136.11].E "sp|Q14103|HNRPD_HUMAN,sp|O14979|HNRDL_HUMAN,tr|H0Y8G5|H0Y8G5_HUMAN,tr|A0A087WUK2|A0A087WUK2_HUMAN,tr|D6RF44|D6RF44_HUMAN,tr|D6RBQ9|D6RBQ9_HUMAN,tr|D6RAF8|D6RAF8_HUMAN,tr|H0YA96|H0YA96_HUMAN" 8 921.5204 1.26 8988 21632 2 921.520392 461.7675 Heterogeneous nuclear ribonucleoprotein D0 OS=Homo sapiens OX=9606 GN=HNRNPD PE=1 SV=1 8.75 3911.3 - 4.44E+06 - - - 0.0184 - 1.547 0.473 - 155.5 1 2 0 0 8 0 0 0 3.89E+08 3.09E+08 - - - 3.8505 0.9992 221125_WJC_METTL3_EV_vs_WT_F01.21636.21636.2 0.000174 18-Dec R.DAVLLLFANK[136.11].Q "sp|P18085|ARF4_HUMAN,tr|C9JPM4|C9JPM4_HUMAN,tr|C9JAK5|C9JAK5_HUMAN,tr|U3KQF2|U3KQF2_HUMAN" 4 1110.6528 0.88 8992 21636 2 1110.657117 556.3337 ADP-ribosylation factor 4 OS=Homo sapiens OX=9606 GN=ARF4 PE=1 SV=3 5.84 3911.6 - 1.28E+06 - - - 3.8455 - 2.491 0.493 - 709.3 1 2 0 0.0043 10 0 0 0 1.84E+07 2.10E+07 - - - 5.2285 0.9999 221125_WJC_METTL3_EV_vs_WT_F01.21637.21637.2 7.09E-05 13/20 R.LSGLLDLALGK.D "sp|P0DTE8|AMY1C_HUMAN,sp|P0DTE7|AMY1B_HUMAN,sp|P0DUB6|AMY1A_HUMAN,tr|A0A804HHZ3|A0A804HHZ3_HUMAN" 4 1098.6649 107.32 8993 21637 2 1098.66527 550.3397 Alpha-amylase 1C OS=Homo sapiens OX=9606 GN=AMY1C PE=1 SV=1 5.84 3911.7 - 1.18E+06 - - - 0.3723 - 2.667 0.417 - 385.7 1 2 0 0.0004 11 0 0 0 8.59E+06 8.00E+04 - - - 4.7745 1 221125_WJC_METTL3_EV_vs_WT_F01.21638.21638.2 1.08E-08 17/30 R.IIGATDSSGELMFLMK.W "sp|P83916|CBX1_HUMAN,sp|Q13185|CBX3_HUMAN,tr|K7ELA4|K7ELA4_HUMAN,tr|J3KS05|J3KS05_HUMAN,tr|B5MD17|B5MD17_HUMAN" 5 1711.8525 1.15 8994 21638 2 1711.849801 856.9335 Chromobox protein homolog 1 OS=Homo sapiens OX=9606 GN=CBX1 PE=1 SV=1 4.37 3911.8 - 1.08E+06 - - - -1.565 - 3.469 0.658 - 745.8 1 2 0 -0.0027 16 0 0 0 6.67E+06 5.82E+06 - - - 6.9582 1 221125_WJC_METTL3_EV_vs_WT_F01.21639.21639.2 3.67E-09 13/30 R.IIGATDSSGELMFLMK[136.11].W "sp|P83916|CBX1_HUMAN,sp|Q13185|CBX3_HUMAN,tr|K7ELA4|K7ELA4_HUMAN,tr|J3KS05|J3KS05_HUMAN,tr|B5MD17|B5MD17_HUMAN" 5 1719.8667 1.15 8995 21639 2 1719.866775 860.9406 Chromobox protein homolog 1 OS=Homo sapiens OX=9606 GN=CBX1 PE=1 SV=1 4.37 3911.9 - 1.07E+06 - - - 0.0552 - 2.772 0.589 - 312.5 1 2 0 0.0001 16 0 0 0 6.67E+06 5.82E+06 - - - 5.898 0.9956 221125_WJC_METTL3_EV_vs_WT_F01.21641.21641.2 0.102 12-Jun K.ELFSFFR.D "sp|Q92576|PHF3_HUMAN,tr|E7ER40|E7ER40_HUMAN,tr|E7EVH3|E7EVH3_HUMAN" 3 944.4756 0.77 8997 21641 2 944.475463 473.2451 PHD finger protein 3 OS=Homo sapiens OX=9606 GN=PHF3 PE=1 SV=3 6.1 3912.1 - 819447 - - - -0.1482 - 1.316 0.174 - 153.1 1 2 0 -0.0001 7 0 0 0 2.91E+06 3.79E+06 - - - 1.1962 0.9995 221125_WJC_METTL3_EV_vs_WT_F01.21642.21642.2 0.00274 20-Aug R.ASILNTWISLK[136.11].Q "sp|P22234|PUR6_HUMAN,tr|D6RF62|D6RF62_HUMAN" 2 1252.7271 0.51 8998 21642 2 1252.728661 627.3708 Multifunctional protein ADE2 OS=Homo sapiens OX=9606 GN=PAICS PE=1 SV=3 8.8 3912.3 - 684872 - - - 1.2676 - 1.958 0.359 - 208.3 1 2 0 0.0016 11 0 0 0 3.30E+06 6.41E+06 - - - 3.5098 0.9998 221125_WJC_METTL3_EV_vs_WT_F01.21644.21644.2 0.331 14/22 K.VAIAENLLDVIK.D sp|Q8WYP5|ELYS_HUMAN 1 1296.7653 0.62 9000 21644 2 1296.766377 649.3899 Protein ELYS OS=Homo sapiens OX=9606 GN=AHCTF1 PE=1 SV=3 4.37 3912.5 - 574442 - - - 0.8282 - 2.836 0.313 - 495.7 1 2 0 0.0011 12 0 0 0 2.62E+06 4.24E+06 - - - 4.0952 0.9998 221125_WJC_METTL3_EV_vs_WT_F01.21645.21645.2 0.00235 18-Oct K.SLESFVELMK.T sp|Q6KB66|K2C80_HUMAN 1 1181.6002 999 9001 21645 2 1181.601085 591.8074 "Keratin, type II cytoskeletal 80 OS=Homo sapiens OX=9606 GN=KRT80 PE=1 SV=2" 4.53 3912.6 - 513484 - - - 0.7397 - 2.174 0.408 - 240.6 1 2 0 0.0009 10 0 0 0 5.31E+06 0.00E+00 - - - 4.2219 0.998 221125_WJC_METTL3_EV_vs_WT_F01.21651.21651.2 0.312 16-Sep K.LLELDSFLK.E "sp|P61289|PSME3_HUMAN,tr|K7ENH2|K7ENH2_HUMAN,tr|K9J957|K9J957_HUMAN,tr|B7Z8D3|B7Z8D3_HUMAN,tr|A0A087WTV2|A0A087WTV2_HUMAN" 5 1076.6118 -1 9007 21651 2 1076.611989 539.3132 Proteasome activator complex subunit 3 OS=Homo sapiens OX=9606 GN=PSME3 PE=1 SV=1 4.37 3913.4 - 284162 - - - 0.2108 - 1.706 0.168 - 162.2 1 2 0 0.0002 9 0 0 0 0.00E+00 0.00E+00 - - - 1.8271 0.9998 221125_WJC_METTL3_EV_vs_WT_F01.21661.21661.2 0.00146 18-Sep R.DALLLIFANK.Q "sp|P36406|TRI23_HUMAN,sp|P62330|ARF6_HUMAN" 2 1116.6543 1.12 9016 21661 2 1116.654366 559.3344 E3 ubiquitin-protein ligase TRIM23 OS=Homo sapiens OX=9606 GN=TRIM23 PE=1 SV=1 5.84 3914.4 - 859194 - - - 0.0627 - 2.297 0.419 - 255.8 1 2 0 0.0001 10 0 0 0 7.76E+06 6.95E+06 - - - 4.457 0.9889 221125_WJC_METTL3_EV_vs_WT_F01.21663.21663.2 7.06E-05 26-Nov Q.GGVLPNIQAVLLPK.K "sp|P16104|H2AX_HUMAN,sp|Q9BTM1|H2AJ_HUMAN,sp|Q93077|H2A1C_HUMAN,sp|Q99878|H2A1J_HUMAN,sp|Q16777|H2A2C_HUMAN,sp|Q8IUE6|H2A2B_HUMAN,sp|Q96QV6|H2A1A_HUMAN,sp|P04908|H2A1B_HUMAN,sp|P20671|H2A1D_HUMAN,sp|P0C0S8|H2A1_HUMAN,sp|Q6FI13|H2A2A_HUMAN,sp|Q96KK5|H2A1H_HUMAN,sp|Q7L7L0|H2A3_HUMAN,tr|A0A0U1RR32|A0A0U1RR32_HUMAN,tr|A0A0U1RRH7|A0A0U1RRH7_HUMAN,tr|H0YFX9|H0YFX9_HUMAN" 16 1417.8657 1.26 9018 21663 2 1417.867073 709.9401 Histone H2AX OS=Homo sapiens OX=9606 GN=H2AX PE=1 SV=2 8.75 3914.6 - 802902 - - - 0.9782 - 1.95 0.523 - 296.6 1 1 0 0.0014 14 0 0 0 8.38E+06 6.67E+06 - - - 4.5793 1 221125_WJC_METTL3_EV_vs_WT_F01.21666.21666.2 6.95E-09 15/32 K.GTVLDQVPVNPSLYLIK.Y "sp|Q5JUX0|SPIN3_HUMAN,sp|Q9Y657|SPIN1_HUMAN" 2 1855.0455 2.85 9021 21666 2 1855.048854 928.53 Spindlin-3 OS=Homo sapiens OX=9606 GN=SPIN3 PE=1 SV=1 5.83 3915 - 529349 - - - 1.8075 - 2.966 0.674 - 395.3 1 2 0 0.0034 17 0 0 0 2.76E+06 9.67E+05 - - - 6.6911 1 221125_WJC_METTL3_EV_vs_WT_F01.21669.21669.2 2.47E-05 14/28 K.ELLFLSNANPSLLER[166.11].H "sp|P51398|RT29_HUMAN,tr|V9GYF7|V9GYF7_HUMAN,tr|V9GYA7|V9GYA7_HUMAN,tr|V9GYW1|V9GYW1_HUMAN,tr|V9GZ61|V9GZ61_HUMAN" 5 1724.9337 0.69 9024 21669 2 1724.942761 863.4741 "28S ribosomal protein S29, mitochondrial OS=Homo sapiens OX=9606 GN=DAP3 PE=1 SV=1" 4.53 3915.4 - 312012 - - - 5.2785 - 2.876 0.617 - 688.9 1 2 0 0.0091 15 0 0 0 1.31E+06 1.91E+06 - - - 6.1925 0.9999 221125_WJC_METTL3_EV_vs_WT_F01.21672.21672.2 2.09E-06 Nov-32 K.GTVLDQVPVNPSLYLIK[136.11].Y "sp|Q5JUX0|SPIN3_HUMAN,sp|Q9Y657|SPIN1_HUMAN" 2 1863.0597 2.85 9027 21672 2 1863.060097 932.5371 Spindlin-3 OS=Homo sapiens OX=9606 GN=SPIN3 PE=1 SV=1 5.83 3915.8 - 235959 - - - 0.2126 - 2.167 0.572 - 191.5 1 2 0 0.0004 17 0 0 0 2.76E+06 9.67E+05 - - - 5.167 1 221125_WJC_METTL3_EV_vs_WT_F01.21675.21675.3 7.00E-05 Dec-52 K.MALVLEALPQIAAK[136.11].L "sp|Q14254|FLOT2_HUMAN,tr|E7EMK3|E7EMK3_HUMAN,tr|J3QLD9|J3QLD9_HUMAN" 3 1474.8673 1.09 9029 21675 3 1474.867278 492.6297 Flotillin-2 OS=Homo sapiens OX=9606 GN=FLOT2 PE=1 SV=2 5.75 3916.3 - 316784 - - - 0.0041 - 2.429 0.456 - 214.3 1 2 0 0 14 0 0 0 1.43E+06 1.32E+06 - - - 5.9825 0.9987 221125_WJC_METTL3_EV_vs_WT_F01.21681.21681.2 8.53E-06 13/28 K.ELLFLSNANPSLLER.H "sp|P51398|RT29_HUMAN,tr|V9GYF7|V9GYF7_HUMAN,tr|V9GYA7|V9GYA7_HUMAN,tr|V9GYW1|V9GYW1_HUMAN,tr|V9GZ61|V9GZ61_HUMAN" 5 1714.9254 -1 9035 21681 2 1714.93345 858.47 "28S ribosomal protein S29, mitochondrial OS=Homo sapiens OX=9606 GN=DAP3 PE=1 SV=1" 4.53 3917 - 612961 - - - 4.7022 - 2.862 0.542 - 620.6 1 2 0 0.0081 15 0 0 0 0.00E+00 0.00E+00 - - - 5.6269 0.9743 221125_WJC_METTL3_EV_vs_WT_F01.21683.21683.2 0.00667 24-Nov N.IVGLVGVDQFLVK.T sp|P13639|EF2_HUMAN 1 1385.8282 -1 9037 21683 2 1385.831509 693.9214 Elongation factor 2 OS=Homo sapiens OX=9606 GN=EEF2 PE=1 SV=4 5.84 3917.2 - 478178 - - - 2.3603 - 2.302 0.45 - 377.7 1 1 0 0.0033 13 0 0 0 0.00E+00 0.00E+00 - - - 4.5036 0.9513 221125_WJC_METTL3_EV_vs_WT_F01.21686.21686.2 0.0013 14-Jun R.NPVWYQAL.T sp|O95373|IPO7_HUMAN 1 989.4971 - 9040 21686 2 989.496745 495.7558 Importin-7 OS=Homo sapiens OX=9606 GN=IPO7 PE=1 SV=1 5.52 3917.6 - 415269 - - - -0.3254 - 1.317 0.358 - 115.4 1 1 0 -0.0003 8 0 0 0 - - - - - 2.5155 1 221125_WJC_METTL3_EV_vs_WT_F01.21688.21688.2 7.44E-10 17/30 K.LFIGGLSFETTEESLR.N "sp|P22626|ROA2_HUMAN,tr|A0A7I2YQN4|A0A7I2YQN4_HUMAN,tr|A0A7I2V4N0|A0A7I2V4N0_HUMAN,tr|A0A7I2V4N1|A0A7I2V4N1_HUMAN,tr|A0A7I2V4I6|A0A7I2V4I6_HUMAN,tr|A0A087WUI2|A0A087WUI2_HUMAN,tr|A0A7I2V4S4|A0A7I2V4S4_HUMAN,tr|A0A7I2V323|A0A7I2V323_HUMAN,tr|A0A7I2V3P1|A0A7I2V3P1_HUMAN,tr|A0A7I2V3P7|A0A7I2V3P7_HUMAN" 10 1797.9149 1.23 9042 21688 2 1797.91344 899.9647 Heterogeneous nuclear ribonucleoproteins A2\B1 OS=Homo sapiens OX=9606 GN=HNRNPA2B1 PE=1 SV=2 4.25 3917.9 - 311946 - - - -0.8009 - 3.233 0.63 - 869 1 2 0 -0.0014 16 0 0 0 5.40E+06 4.39E+06 - - - 6.5786 0.9989 221125_WJC_METTL3_EV_vs_WT_F01.21689.21689.2 0.000508 22-Sep K.VPGLYVIDSIVR[166.11].Q "sp|O95104|SCAF4_HUMAN,sp|Q9UPN6|SCAF8_HUMAN,tr|A0A0A0MT33|A0A0A0MT33_HUMAN" 3 1339.7739 1.97 9043 21689 2 1339.77798 670.8942 SR-related and CTD-associated factor 4 OS=Homo sapiens OX=9606 GN=SCAF4 PE=1 SV=3 5.81 3918 - 263329 - - - 3.0401 - 1.937 0.427 - 257.9 1 2 0 0.0041 12 0 0 0 3.80E+06 1.93E+06 - - - 3.9331 1 221125_WJC_METTL3_EV_vs_WT_F01.21690.21690.2 1.27E-10 18/30 K.LFIGGLSFETTEESLR[166.11].N "sp|P22626|ROA2_HUMAN,tr|A0A7I2YQN4|A0A7I2YQN4_HUMAN,tr|A0A7I2V4N0|A0A7I2V4N0_HUMAN,tr|A0A7I2V4N1|A0A7I2V4N1_HUMAN,tr|A0A7I2V4I6|A0A7I2V4I6_HUMAN,tr|A0A087WUI2|A0A087WUI2_HUMAN,tr|A0A7I2V4S4|A0A7I2V4S4_HUMAN,tr|A0A7I2V323|A0A7I2V323_HUMAN,tr|A0A7I2V3P1|A0A7I2V3P1_HUMAN,tr|A0A7I2V3P7|A0A7I2V3P7_HUMAN" 10 1807.9232 1.23 9044 21690 2 1807.923842 904.9689 Heterogeneous nuclear ribonucleoproteins A2\B1 OS=Homo sapiens OX=9606 GN=HNRNPA2B1 PE=1 SV=2 4.25 3918.1 - 241007 - - - 0.3828 - 3.412 0.638 - 1100.4 1 2 0 0.0007 16 0 0 0 5.40E+06 4.39E+06 - - - 6.7704 0.9996 221125_WJC_METTL3_EV_vs_WT_F01.21695.21695.2 0.126 18-Sep R.DALLLIFANK[136.11].Q "sp|P36406|TRI23_HUMAN,sp|P62330|ARF6_HUMAN" 2 1124.6685 1.12 9048 21695 2 1124.669082 563.3415 E3 ubiquitin-protein ligase TRIM23 OS=Homo sapiens OX=9606 GN=TRIM23 PE=1 SV=1 5.84 3918.7 - 1.57E+06 - - - 0.521 - 2.095 0.291 - 231.3 1 2 0 0.0006 10 0 0 0 7.76E+06 6.95E+06 - - - 3.2545 1 221125_WJC_METTL3_EV_vs_WT_F01.21700.21700.2 2.37E-07 17/30 L.SLGIETAGGVMTVLIK[136.11].R "sp|P11142|HSP7C_HUMAN,tr|E9PNE6|E9PNE6_HUMAN,tr|A8K7Q2|A8K7Q2_HUMAN,tr|E9PKE3|E9PKE3_HUMAN" 4 1595.9048 0.05 9053 21700 2 1595.907079 798.9597 Heat shock cognate 71 kDa protein OS=Homo sapiens OX=9606 GN=HSPA8 PE=1 SV=1 5.72 3919.1 - 826000 - - - 1.4406 - 3.301 0.671 - 794.5 1 1 0 0.0023 16 0 0 0 1.51E+05 3.08E+06 - - - 6.9323 0.9999 221125_WJC_METTL3_EV_vs_WT_F01.21701.21701.3 3.68E-07 Oct-60 K.LFIGGLSFETTEESLR.N "sp|P22626|ROA2_HUMAN,tr|A0A7I2YQN4|A0A7I2YQN4_HUMAN,tr|A0A7I2V4N0|A0A7I2V4N0_HUMAN,tr|A0A7I2V4N1|A0A7I2V4N1_HUMAN,tr|A0A7I2V4I6|A0A7I2V4I6_HUMAN,tr|A0A087WUI2|A0A087WUI2_HUMAN,tr|A0A7I2V4S4|A0A7I2V4S4_HUMAN,tr|A0A7I2V323|A0A7I2V323_HUMAN,tr|A0A7I2V3P1|A0A7I2V3P1_HUMAN,tr|A0A7I2V3P7|A0A7I2V3P7_HUMAN" 10 1797.9149 1.63 9054 21701 3 1797.917979 600.3122 Heterogeneous nuclear ribonucleoproteins A2\B1 OS=Homo sapiens OX=9606 GN=HNRNPA2B1 PE=1 SV=2 4.25 3919.3 - 683147 - - - 1.7237 - 2.279 0.518 - 119.5 1 2 0 0.0031 16 0 0 0 1.40E+06 8.56E+05 - - - 6.4279 1 221125_WJC_METTL3_EV_vs_WT_F01.21704.21704.2 1.06E-09 30-Dec R.IMEGPAFNFLDAPAVR.V sp|P11177|ODPB_HUMAN 1 1746.8763 1.36 9057 21704 2 1746.88085 874.4454 "Pyruvate dehydrogenase E1 component subunit beta, mitochondrial OS=Homo sapiens OX=9606 GN=PDHB PE=1 SV=3" 4.37 3919.6 - 556587 - - - 2.5892 - 2.75 0.619 - 398.8 1 2 0 0.0045 16 0 0 0 1.99E+06 1.47E+06 - - - 6.0986 0.9876 221125_WJC_METTL3_EV_vs_WT_F01.21705.21705.3 0.000308 Dec-52 K.MALVLEALPQIAAK.L "sp|Q14254|FLOT2_HUMAN,tr|E7EMK3|E7EMK3_HUMAN,tr|J3QLD9|J3QLD9_HUMAN" 3 1466.8531 1.01 9058 21705 3 1466.860105 489.9583 Flotillin-2 OS=Homo sapiens OX=9606 GN=FLOT2 PE=1 SV=2 5.75 3919.8 - 550780 - - - 4.7946 - 2.337 0.234 - 206.4 1 2 0 0.007 14 0 0 0 1.43E+06 1.42E+06 - - - 3.4028 1 221125_WJC_METTL3_EV_vs_WT_F01.21708.21708.2 1.42E-10 16/30 R.IMEGPAFNFLDAPAVR[166.11].V sp|P11177|ODPB_HUMAN 1 1756.8846 -1 9061 21708 2 1756.890067 879.4496 "Pyruvate dehydrogenase E1 component subunit beta, mitochondrial OS=Homo sapiens OX=9606 GN=PDHB PE=1 SV=3" 4.37 3920.2 - 423214 - - - 3.1135 - 3.025 0.667 - 822 1 2 0 0.0055 16 0 0 0 0.00E+00 0.00E+00 - - - 6.6871 0.999 221125_WJC_METTL3_EV_vs_WT_F01.21709.21709.3 0.00504 Oct-60 K.LFIGGLSFETTEESLR[166.11].N "sp|P22626|ROA2_HUMAN,tr|A0A7I2YQN4|A0A7I2YQN4_HUMAN,tr|A0A7I2V4N0|A0A7I2V4N0_HUMAN,tr|A0A7I2V4N1|A0A7I2V4N1_HUMAN,tr|A0A7I2V4I6|A0A7I2V4I6_HUMAN,tr|A0A087WUI2|A0A087WUI2_HUMAN,tr|A0A7I2V4S4|A0A7I2V4S4_HUMAN,tr|A0A7I2V323|A0A7I2V323_HUMAN,tr|A0A7I2V3P1|A0A7I2V3P1_HUMAN,tr|A0A7I2V3P7|A0A7I2V3P7_HUMAN" 10 1807.9232 -1 9062 21709 3 1807.926698 603.6483 Heterogeneous nuclear ribonucleoproteins A2\B1 OS=Homo sapiens OX=9606 GN=HNRNPA2B1 PE=1 SV=2 4.25 3920.3 - 419850 - - - 1.9625 - 1.982 0.313 - 90 1 2 0 0.0035 16 0 0 0 0.00E+00 0.00E+00 - - - 3.784 0.9997 221125_WJC_METTL3_EV_vs_WT_F01.21712.21712.3 1.84E-05 Dec-60 R.IMEGPAFNFLDAPAVR.V sp|P11177|ODPB_HUMAN 1 1746.8763 1.32 9065 21712 3 1746.882367 583.2994 "Pyruvate dehydrogenase E1 component subunit beta, mitochondrial OS=Homo sapiens OX=9606 GN=PDHB PE=1 SV=3" 4.37 3920.7 - 379134 - - - 3.4576 - 2.469 0.445 - 145.4 1 2 0 0.006 16 0 0 0 1.21E+06 9.12E+05 - - - 5.8187 0.9998 221125_WJC_METTL3_EV_vs_WT_F01.21721.21721.2 4.95E-06 18-Nov K.FDMIVPILEK[136.11].M "sp|Q13418|ILK_HUMAN,tr|A0A0A0MTH3|A0A0A0MTH3_HUMAN" 2 1211.6715 0.48 9073 21721 2 1211.672818 606.843 Integrin-linked protein kinase OS=Homo sapiens OX=9606 GN=ILK PE=1 SV=2 4.37 3921.9 - 680458 - - - 1.0613 - 2.089 0.53 - 450.1 1 2 0 0.0013 10 0 0 0 1.32E+06 2.75E+06 - - - 5.0115 0.9988 221125_WJC_METTL3_EV_vs_WT_F01.21726.21726.2 0.00626 26-Aug K.MGIYYIPVLGPAPR[166.11].W sp|Q9BSC4|NOL10_HUMAN 1 1555.846 -1 9078 21726 2 1555.843235 778.9303 Nucleolar protein 10 OS=Homo sapiens OX=9606 GN=NOL10 PE=1 SV=1 8.34 3922.5 - 306162 - - - -1.7939 - 1.377 0.398 - 105.5 1 2 0 -0.0028 14 0 0 0 0.00E+00 0.00E+00 - - - 2.7825 0.9983 221125_WJC_METTL3_EV_vs_WT_F01.21729.21729.2 0.491 14-Sep K.ISLIQIFR.A "sp|Q6P2Q9|PRP8_HUMAN,tr|I3L3Z8|I3L3Z8_HUMAN" 2 988.607 -1 9081 21729 2 988.608655 495.3108 Pre-mRNA-processing-splicing factor 8 OS=Homo sapiens OX=9606 GN=PRPF8 PE=1 SV=2 9.75 3922.9 - 291355 - - - 1.7226 - 1.77 0.236 - 227.7 1 2 0 0.0017 8 0 0 0 0.00E+00 0.00E+00 - - - 2.5056 0.9999 221125_WJC_METTL3_EV_vs_WT_F01.21730.21730.2 1.01E-08 30-Nov K.LFIGGLSFETTDDSLR[166.11].E "sp|P51991|ROA3_HUMAN,tr|A0A7I2V5D8|A0A7I2V5D8_HUMAN,tr|A0A7I2V2R3|A0A7I2V2R3_HUMAN,tr|A0A7I2V4J6|A0A7I2V4J6_HUMAN,tr|A0A7I2V4G0|A0A7I2V4G0_HUMAN,tr|A0A7I2V402|A0A7I2V402_HUMAN" 6 1779.8918 -1 9082 21730 2 1779.892781 890.9532 Heterogeneous nuclear ribonucleoprotein A3 OS=Homo sapiens OX=9606 GN=HNRNPA3 PE=1 SV=2 4.03 3923 - 286604 - - - 0.5231 - 2.505 0.572 - 179.2 1 2 0 0.0009 16 0 0 0 0.00E+00 0.00E+00 - - - 5.5232 0.9992 221125_WJC_METTL3_EV_vs_WT_F01.21732.21732.2 0.0135 14-Sep K.ISLIQIFR[166.11].A "sp|Q6P2Q9|PRP8_HUMAN,tr|I3L3Z8|I3L3Z8_HUMAN" 2 998.6152 -1 9084 21732 2 998.615134 500.3149 Pre-mRNA-processing-splicing factor 8 OS=Homo sapiens OX=9606 GN=PRPF8 PE=1 SV=2 9.75 3923.3 - 266116 - - - -0.0881 - 1.954 0.209 - 224.9 1 2 0 -0.0001 8 0 0 0 0.00E+00 0.00E+00 - - - 2.605 0.9974 221125_WJC_METTL3_EV_vs_WT_F01.21738.21738.2 0.661 20-Oct K.LALGIPLPELR.N "sp|P27708|PYR1_HUMAN,tr|F8VPD4|F8VPD4_HUMAN" 2 1190.7387 0.49 9089 21738 2 1190.742036 596.3766 CAD protein OS=Homo sapiens OX=9606 GN=CAD PE=1 SV=3 6 3924 - 1.09E+06 - - - 2.8067 - 2.095 0.234 - 267.3 1 2 0 0.0033 11 0 0 0 3.46E+06 7.09E+06 - - - 2.7689 0.9485 221125_WJC_METTL3_EV_vs_WT_F01.21741.21741.2 0.655 18-Jun K.INGYSK[136.11]KDSR.Q sp|P35556|FBN2_HUMAN 1 1174.6186 - 9092 21741 2 1174.617555 588.3166 Fibrillin-2 OS=Homo sapiens OX=9606 GN=FBN2 PE=1 SV=3 9.7 3924.2 - 2.35E+06 - - - -0.8777 - 1.424 0.18 - 66.7 2 2 1 -0.001 10 0 0 0 - - - - - 1.2223 0.999 221125_WJC_METTL3_EV_vs_WT_F01.21742.21742.2 0.00501 14/20 K.LALGIPLPELR[166.11].N "sp|P27708|PYR1_HUMAN,tr|F8VPD4|F8VPD4_HUMAN" 2 1200.747 0.49 9093 21742 2 1200.748079 601.3808 CAD protein OS=Homo sapiens OX=9606 GN=CAD PE=1 SV=3 6 3924.2 - 2.29E+06 - - - 0.9286 - 2.351 0.169 - 672.4 1 2 0 0.0011 11 0 0 0 3.46E+06 7.09E+06 - - - 2.6014 0.9942 221125_WJC_METTL3_EV_vs_WT_F01.21755.21755.2 0.0186 24-Jul K.LVSDEMVVELIEK.N "sp|P54819|KAD2_HUMAN,tr|A0A5F9ZHP2|A0A5F9ZHP2_HUMAN,tr|G3V213|G3V213_HUMAN,tr|F8W1A4|F8W1A4_HUMAN,tr|F8VZG5|F8VZG5_HUMAN" 5 1502.7902 -1 9106 21755 2 1502.793416 752.4024 "Adenylate kinase 2, mitochondrial OS=Homo sapiens OX=9606 GN=AK2 PE=1 SV=2" 4 3925.5 - 410518 - - - 2.142 - 1.204 0.311 - 69.5 2 2 0 0.0032 13 0 0 0 0.00E+00 0.00E+00 - - - 1.679 0.9999 221125_WJC_METTL3_EV_vs_WT_F01.21756.21756.2 8.86E-06 18-Nov K.ADLTALFLPR.Q sp|Q13045|FLII_HUMAN 1 1115.6339 0.84 9107 21756 2 1115.635527 558.8242 Protein flightless-1 homolog OS=Homo sapiens OX=9606 GN=FLII PE=1 SV=2 5.88 3925.6 - 402309 - - - 1.4628 - 2.629 0.527 - 426.1 1 2 0 0.0016 10 0 0 0 6.53E+06 7.82E+06 - - - 5.631 0.9999 221125_WJC_METTL3_EV_vs_WT_F01.21762.21762.2 1.75E-06 18-Nov K.ADLTALFLPR[166.11].Q sp|Q13045|FLII_HUMAN 1 1125.6422 0.84 9112 21762 2 1125.643574 563.8284 Protein flightless-1 homolog OS=Homo sapiens OX=9606 GN=FLII PE=1 SV=2 5.88 3926.2 - 1.26E+06 - - - 1.2517 - 2.651 0.497 - 450.1 1 2 0 0.0014 10 0 0 0 6.53E+06 7.82E+06 - - - 5.4327 0.9999 221125_WJC_METTL3_EV_vs_WT_F01.21771.21771.2 4.80E-06 26-Dec R.ISATSIFFESMPYK[136.11].L "sp|P34897|GLYM_HUMAN,sp|P34896|GLYC_HUMAN,tr|G3V4W5|G3V4W5_HUMAN,tr|G3V2D2|G3V2D2_HUMAN,tr|G3V5L0|G3V5L0_HUMAN,tr|G3V2Y4|G3V2Y4_HUMAN,tr|G3V540|G3V540_HUMAN" 7 1627.8047 -1 9121 21771 2 1627.805587 814.9096 "Serine hydroxymethyltransferase, mitochondrial OS=Homo sapiens OX=9606 GN=SHMT2 PE=1 SV=3" 6 3927.2 - 322580 - - - 0.5252 - 2.511 0.517 - 432.4 1 2 0 0.0009 14 0 0 0 0.00E+00 0.00E+00 - - - 5.1697 0.9999 221125_WJC_METTL3_EV_vs_WT_F01.21772.21772.2 7.64E-05 24-Nov R.VFNVFC[160.03]LYGNVEK[136.11].V "sp|P14866|HNRPL_HUMAN,tr|M0QYT0|M0QYT0_HUMAN,tr|A0A3B3ITJ4|A0A3B3ITJ4_HUMAN,tr|M0QXS5|M0QXS5_HUMAN,tr|M0R076|M0R076_HUMAN" 5 1595.7897 -1 9122 21772 2 1595.788886 798.9022 Heterogeneous nuclear ribonucleoprotein L OS=Homo sapiens OX=9606 GN=HNRNPL PE=1 SV=2 5.96 3927.4 - 301702 - - - -0.5414 - 2.416 0.556 - 398.2 1 2 0 -0.0009 13 0 0 0 0.00E+00 0.00E+00 - - - 5.4113 0.9998 221125_WJC_METTL3_EV_vs_WT_F01.21775.21775.2 0.000817 30-Aug R.MLAMPIDLDTLSPEER.R "sp|Q7Z7F7|RM55_HUMAN,tr|X6R631|X6R631_HUMAN" 2 1829.8903 -1 9125 21775 2 1829.887526 915.9524 "39S ribosomal protein L55, mitochondrial OS=Homo sapiens OX=9606 GN=MRPL55 PE=1 SV=1" 3.92 3927.7 - 182452 - - - -1.528 - 1.809 0.534 - 144.5 1 2 0 -0.0028 16 0 0 0 0.00E+00 0.00E+00 - - - 4.4416 1 221125_WJC_METTL3_EV_vs_WT_F01.21782.21782.2 5.09E-07 13/26 K.LYSPSQIGAFVLMK[136.11].M "sp|P38646|GRP75_HUMAN,tr|H0Y8K0|H0Y8K0_HUMAN,tr|A0A7I2V2S7|A0A7I2V2S7_HUMAN,tr|A0A7I2V2G2|A0A7I2V2G2_HUMAN,tr|A0A3B3ITI4|A0A3B3ITI4_HUMAN,tr|A0A7I2V3F7|A0A7I2V3F7_HUMAN,tr|A0A7I2YQB2|A0A7I2YQB2_HUMAN,tr|D6RCD7|D6RCD7_HUMAN" 8 1560.8465 0.36 9131 21782 2 1560.846841 781.4305 "Stress-70 protein, mitochondrial OS=Homo sapiens OX=9606 GN=HSPA9 PE=1 SV=2" 8.59 3928.5 - 1.84E+06 - - - 0.1948 - 2.811 0.577 - 578 1 2 0 0.0003 14 0 0 0 1.37E+07 3.84E+07 - - - 5.8962 0.9997 221125_WJC_METTL3_EV_vs_WT_F01.21784.21784.2 2.85E-05 16-Sep R.NLPFDFTWK[136.11].M "sp|P52272|HNRPM_HUMAN,tr|M0R2I7|M0R2I7_HUMAN,tr|M0QY96|M0QY96_HUMAN,tr|A0A087X0X3|A0A087X0X3_HUMAN" 4 1174.5902 1.71 9133 21784 2 1174.592074 588.3024 Heterogeneous nuclear ribonucleoprotein M OS=Homo sapiens OX=9606 GN=HNRNPM PE=1 SV=3 5.84 3928.6 - 1.03E+06 - - - 1.5563 - 1.7 0.499 - 250.2 1 2 0 0.0018 9 0 0 0 8.83E+07 5.16E+07 - - - 4.2612 0.9997 221125_WJC_METTL3_EV_vs_WT_F01.21785.21785.2 0.0123 18-Oct K.VLLDIFTGVR[166.11].L sp|P49916|DNLI3_HUMAN 1 1141.6735 -1 9134 21785 2 1141.673817 571.844 DNA ligase 3 OS=Homo sapiens OX=9606 GN=LIG3 PE=1 SV=2 5.81 3928.7 - 1.01E+06 - - - 0.3083 - 2.172 0.329 - 326.6 1 2 0 0.0004 10 0 0 0 0.00E+00 0.00E+00 - - - 3.636 0.9989 221125_WJC_METTL3_EV_vs_WT_F01.21786.21786.2 0.00309 16-Nov R.DILALMEVK.M sp|Q96EK4|THA11_HUMAN 1 1030.5733 -1 9135 21786 2 1030.574816 516.2939 THAP domain-containing protein 11 OS=Homo sapiens OX=9606 GN=THAP11 PE=1 SV=2 4.37 3928.8 - 889712 - - - 1.5021 - 2.047 0.231 - 363.6 1 2 0 0.0015 9 0 0 0 0.00E+00 0.00E+00 - - - 2.8192 0.9875 221125_WJC_METTL3_EV_vs_WT_F01.21787.21787.2 5.47E-05 20-Jul K.IIHDFPQFYPL.G "sp|P35244|RFA3_HUMAN,tr|B5MC59|B5MC59_HUMAN" 2 1388.7129 - 9136 21787 2 1388.713019 695.3637 Replication protein A 14 kDa subunit OS=Homo sapiens OX=9606 GN=RPA3 PE=1 SV=1 5.08 3928.9 - 878193 - - - 0.1051 - 1.812 0.456 - 119 1 1 0 0.0001 11 0 0 0 - - - - - 4.017 0.9992 221125_WJC_METTL3_EV_vs_WT_F01.21789.21789.2 0.0939 16-Sep K.ILNIFGVIK.G "sp|P02786|TFR1_HUMAN,tr|G3V0E5|G3V0E5_HUMAN" 2 1015.643 -1 9138 21789 2 1015.64314 508.8288 Transferrin receptor protein 1 OS=Homo sapiens OX=9606 GN=TFRC PE=1 SV=2 8.75 3929.2 - 830470 - - - 0.1349 - 1.81 0.253 - 164.4 1 2 0 0.0001 9 0 0 0 0.00E+00 0.00E+00 - - - 2.6261 0.9998 221125_WJC_METTL3_EV_vs_WT_F01.21790.21790.2 0.0426 16-Oct K.ILNIFGVIK[136.11].G "sp|P02786|TFR1_HUMAN,tr|G3V0E5|G3V0E5_HUMAN" 2 1023.6572 -1 9139 21790 2 1023.657062 512.8359 Transferrin receptor protein 1 OS=Homo sapiens OX=9606 GN=TFRC PE=1 SV=2 8.75 3929.3 - 812832 - - - -0.1377 - 1.936 0.401 - 220.8 1 2 0 -0.0001 9 0 0 0 0.00E+00 0.00E+00 - - - 3.914 1 221125_WJC_METTL3_EV_vs_WT_F01.21791.21791.3 8.16E-10 16/48 K.LFYADHPFIFLVR.D "sp|P50454|SERPH_HUMAN,tr|E9PKH2|E9PKH2_HUMAN,tr|H0YEP8|H0YEP8_HUMAN" 3 1636.8766 1.57 9140 21791 3 1636.878109 546.6328 Serpin H1 OS=Homo sapiens OX=9606 GN=SERPINH1 PE=1 SV=2 6.74 3929.4 - 647916 - - - 0.931 - 3.076 0.529 - 295.5 1 2 0 0.0015 13 0 0 0 7.34E+06 4.67E+06 - - - 7.4839 1 221125_WJC_METTL3_EV_vs_WT_F01.21792.21792.3 5.32E-10 16/48 K.LFYADHPFIFLVR[166.11].D "sp|P50454|SERPH_HUMAN,tr|E9PKH2|E9PKH2_HUMAN,tr|H0YEP8|H0YEP8_HUMAN" 3 1646.8849 1.57 9141 21792 3 1646.885589 549.9689 Serpin H1 OS=Homo sapiens OX=9606 GN=SERPINH1 PE=1 SV=2 6.74 3929.5 - 527493 - - - 0.4457 - 3.25 0.581 - 293.6 1 2 0 0.0007 13 0 0 0 7.34E+06 4.67E+06 - - - 8.213 0.9997 221125_WJC_METTL3_EV_vs_WT_F01.21795.21795.2 0.0232 18-Nov R.NFIVWLEDQK.L "sp|Q9Y224|RTRAF_HUMAN,tr|G3V4C6|G3V4C6_HUMAN,tr|G3V4E7|G3V4E7_HUMAN" 3 1290.6608 -1 9144 21795 2 1290.659865 646.3377 "RNA transcription, translation and transport factor protein OS=Homo sapiens OX=9606 GN=RTRAF PE=1 SV=1" 4.37 3929.9 - 450352 - - - -0.7539 - 2.13 0.365 - 453.6 1 2 0 -0.001 10 0 0 0 0.00E+00 0.00E+00 - - - 3.8472 1 221125_WJC_METTL3_EV_vs_WT_F01.21803.21803.2 1.32E-06 13/26 K.LYSPSQIGAFVLMK.M "sp|P38646|GRP75_HUMAN,tr|H0Y8K0|H0Y8K0_HUMAN,tr|A0A7I2V2S7|A0A7I2V2S7_HUMAN,tr|A0A7I2V2G2|A0A7I2V2G2_HUMAN,tr|A0A3B3ITI4|A0A3B3ITI4_HUMAN,tr|A0A7I2V3F7|A0A7I2V3F7_HUMAN,tr|A0A7I2YQB2|A0A7I2YQB2_HUMAN,tr|D6RCD7|D6RCD7_HUMAN" 8 1552.8323 0.36 9151 21803 2 1552.830377 777.4234 "Stress-70 protein, mitochondrial OS=Homo sapiens OX=9606 GN=HSPA9 PE=1 SV=2" 8.59 3930.9 - 2.31E+06 - - - -1.2622 - 2.757 0.601 - 519.1 1 2 0 -0.002 14 0 0 0 1.36E+07 3.83E+07 - - - 6.0243 0.9999 221125_WJC_METTL3_EV_vs_WT_F01.21804.21804.3 0.000272 Sep-52 K.LYSPSQIGAFVLMK[136.11].M "sp|P38646|GRP75_HUMAN,tr|H0Y8K0|H0Y8K0_HUMAN,tr|A0A7I2V2S7|A0A7I2V2S7_HUMAN,tr|A0A7I2V2G2|A0A7I2V2G2_HUMAN,tr|A0A3B3ITI4|A0A3B3ITI4_HUMAN,tr|A0A7I2V3F7|A0A7I2V3F7_HUMAN,tr|A0A7I2YQB2|A0A7I2YQB2_HUMAN,tr|D6RCD7|D6RCD7_HUMAN" 8 1560.8465 0.37 9152 21804 3 1560.843764 521.2895 "Stress-70 protein, mitochondrial OS=Homo sapiens OX=9606 GN=HSPA9 PE=1 SV=2" 8.59 3931 - 1.85E+06 - - - -1.7766 - 2.228 0.417 - 123.4 1 2 0 -0.0028 14 0 0 0 4.21E+06 1.12E+07 - - - 5.3173 1 221125_WJC_METTL3_EV_vs_WT_F01.21805.21805.3 3.56E-09 16/60 R.NVQALEIELQSQLALK.Q "sp|P13645|K1C10_HUMAN,tr|A0A1B0GVI3|A0A1B0GVI3_HUMAN" 2 1796.0044 999 9153 21805 3 1796.002929 599.6754 "Keratin, type I cytoskeletal 10 OS=Homo sapiens OX=9606 GN=KRT10 PE=1 SV=6" 4.53 3931 - 1.54E+06 - - - -0.799 - 3.349 0.567 - 419.9 1 2 0 -0.0014 16 0 0 0 1.94E+07 0.00E+00 - - - 7.9624 0.9977 221125_WJC_METTL3_EV_vs_WT_F01.21808.21808.2 0.0777 18-Sep R.NFIVWLEDQK[136.11].L "sp|Q9Y224|RTRAF_HUMAN,tr|G3V4C6|G3V4C6_HUMAN,tr|G3V4E7|G3V4E7_HUMAN" 3 1298.675 1.3 9156 21808 2 1298.676934 650.3448 "RNA transcription, translation and transport factor protein OS=Homo sapiens OX=9606 GN=RTRAF PE=1 SV=1" 4.37 3931.3 - 1.05E+06 - - - 1.4599 - 1.551 0.246 - 307.6 1 2 0 0.0019 10 0 0 0 2.76E+06 2.13E+06 - - - 2.0825 0.9986 221125_WJC_METTL3_EV_vs_WT_F01.21809.21809.2 0.000147 22-Nov R.TLITFAGMIPYR.T "sp|Q8N1F7|NUP93_HUMAN,tr|H3BV15|H3BV15_HUMAN" 2 1381.7428 -1 9157 21809 2 1381.739163 691.8787 Nuclear pore complex protein Nup93 OS=Homo sapiens OX=9606 GN=NUP93 PE=1 SV=2 8.41 3931.4 - 981245 - - - -2.6271 - 2.362 0.261 - 436.7 1 2 0 -0.0036 12 0 0 0 0.00E+00 0.00E+00 - - - 3.2291 0.9999 221125_WJC_METTL3_EV_vs_WT_F01.21810.21810.3 1.85E-05 14/52 K.LYSPSQIGAFVLMK.M "sp|P38646|GRP75_HUMAN,tr|H0Y8K0|H0Y8K0_HUMAN,tr|A0A7I2V2S7|A0A7I2V2S7_HUMAN,tr|A0A7I2V2G2|A0A7I2V2G2_HUMAN,tr|A0A3B3ITI4|A0A3B3ITI4_HUMAN,tr|A0A7I2V3F7|A0A7I2V3F7_HUMAN,tr|A0A7I2YQB2|A0A7I2YQB2_HUMAN,tr|D6RCD7|D6RCD7_HUMAN" 8 1552.8323 0.37 9158 21810 3 1552.830368 518.6181 "Stress-70 protein, mitochondrial OS=Homo sapiens OX=9606 GN=HSPA9 PE=1 SV=2" 8.59 3931.5 - 826108 - - - -1.268 - 2.172 0.45 - 272.6 1 2 0 -0.002 14 0 0 0 4.21E+06 1.12E+07 - - - 5.6178 1 221125_WJC_METTL3_EV_vs_WT_F01.21815.21815.2 6.81E-05 14/24 R.LGGLDVLEAEFSK.T sp|Q5SGD2|PPM1L_HUMAN 1 1376.7187 -1 9163 21815 2 1376.71695 689.3666 Protein phosphatase 1L OS=Homo sapiens OX=9606 GN=PPM1L PE=1 SV=1 4.14 3932.1 - 489380 - - - -1.3053 - 2.812 0.559 - 845.4 1 2 0 -0.0018 13 0 0 0 0.00E+00 0.00E+00 - - - 5.8227 0.999 221125_WJC_METTL3_EV_vs_WT_F01.21817.21817.2 0.00533 18-Nov R.LLELQYFISR.D "sp|Q92896|GSLG1_HUMAN,tr|H3BM42|H3BM42_HUMAN" 2 1280.7129 -1 9165 21817 2 1280.709569 641.3637 Golgi apparatus protein 1 OS=Homo sapiens OX=9606 GN=GLG1 PE=1 SV=2 6 3932.4 - 318761 - - - -2.5798 - 2.23 0.305 - 572.6 1 2 0 -0.0033 10 0 0 0 0.00E+00 0.00E+00 - - - 3.5313 1 221125_WJC_METTL3_EV_vs_WT_F01.21823.21823.2 0.000392 16/30 R.NVQALEIELQSQLALK.Q "sp|P13645|K1C10_HUMAN,tr|A0A1B0GVI3|A0A1B0GVI3_HUMAN" 2 1796.0044 999 9170 21823 2 1796.003043 899.0095 "Keratin, type I cytoskeletal 10 OS=Homo sapiens OX=9606 GN=KRT10 PE=1 SV=6" 4.53 3933.1 - 1.89E+06 - - - -0.7355 - 3.587 0.601 - 965.4 1 2 0 -0.0013 16 0 0 0 3.99E+06 0.00E+00 - - - 6.6199 0.9998 221125_WJC_METTL3_EV_vs_WT_F01.21824.21824.2 6.35E-06 20-Oct K.SVFGGLVNYFK[136.11].S "sp|O95721|SNP29_HUMAN,tr|C9JAF7|C9JAF7_HUMAN" 2 1237.6587 1.86 9171 21824 2 1237.658182 619.8366 Synaptosomal-associated protein 29 OS=Homo sapiens OX=9606 GN=SNAP29 PE=1 SV=1 8.31 3933.1 - 1.83E+06 - - - -0.3854 - 1.871 0.509 - 245.5 1 2 0 -0.0005 11 0 0 0 8.73E+06 4.68E+06 - - - 4.4951 0.9596 221125_WJC_METTL3_EV_vs_WT_F01.21825.21825.2 5.17E-05 18-Aug K.VDLKPLLSSL.S "sp|Q9NRA8|4ET_HUMAN,tr|B1AKL4|B1AKL4_HUMAN,tr|B0QYZ7|B0QYZ7_HUMAN" 3 1083.654 -1 9172 21825 2 1083.653744 542.8343 Eukaryotic translation initiation factor 4E transporter OS=Homo sapiens OX=9606 GN=EIF4ENIF1 PE=1 SV=2 5.81 3933.2 - 1.73E+06 - - - -0.2012 - 1.938 0.244 - 143.6 1 1 0 -0.0002 10 0 0 0 0.00E+00 0.00E+00 - - - 2.69 0.9999 221125_WJC_METTL3_EV_vs_WT_F01.21827.21827.2 7.20E-05 22-Nov K.ITVNEVELLVMK[136.11].A "sp|Q9UNM6|PSD13_HUMAN,tr|A0A087WUL9|A0A087WUL9_HUMAN" 2 1394.7934 -1 9174 21827 2 1394.792311 698.404 26S proteasome non-ATPase regulatory subunit 13 OS=Homo sapiens OX=9606 GN=PSMD13 PE=1 SV=2 4.53 3933.4 - 1.01E+06 - - - -0.8087 - 2.589 0.494 - 420.7 1 2 0 -0.0011 12 0 0 0 0.00E+00 0.00E+00 - - - 5.1923 0.9996 221125_WJC_METTL3_EV_vs_WT_F01.21828.21828.2 0.0311 18-Sep K.LLELQELVLR.L "sp|Q08379|GOGA2_HUMAN,tr|A0A6Q8KRG2|A0A6Q8KRG2_HUMAN,tr|A0A087WYC0|A0A087WYC0_HUMAN" 3 1224.7442 -1 9175 21828 2 1224.743035 613.3794 Golgin subfamily A member 2 OS=Homo sapiens OX=9606 GN=GOLGA2 PE=1 SV=3 4.53 3933.5 - 941834 - - - -0.93 - 2.061 0.309 - 230.7 1 2 0 -0.0011 10 0 0 0 0.00E+00 0.00E+00 - - - 3.3416 0.9979 221125_WJC_METTL3_EV_vs_WT_F01.21831.21831.3 2.80E-06 18/60 L.SLGLETAGGVMTALIK[136.11].R "sp|P0DMV8|HS71A_HUMAN,sp|P34931|HS71L_HUMAN,sp|P0DMV9|HS71B_HUMAN,tr|Q53FA3|Q53FA3_HUMAN,tr|V9GZ37|V9GZ37_HUMAN,tr|A0A0G2JIW1|A0A0G2JIW1_HUMAN" 6 1567.8735 -1 9178 21831 3 1567.871839 523.6318 Heat shock 70 kDa protein 1A OS=Homo sapiens OX=9606 GN=HSPA1A PE=1 SV=1 5.72 3933.9 - 624813 - - - -1.0466 - 3.124 0.504 - 377 1 1 0 -0.0016 16 0 0 0 0.00E+00 0.00E+00 - - - 7.0815 0.9945 221125_WJC_METTL3_EV_vs_WT_F01.21836.21836.2 0.129 26-Oct K.LAGLVEELEADEWR[166.11].F "sp|Q96DE5|APC16_HUMAN,tr|A0A087WUN5|A0A087WUN5_HUMAN" 2 1638.8129 0.63 9183 21836 2 1638.80875 820.4137 Anaphase-promoting complex subunit 16 OS=Homo sapiens OX=9606 GN=ANAPC16 PE=1 SV=1 3.91 3934.5 - 347360 - - - -2.5152 - 1.587 0.23 - 250.8 1 2 0 -0.0041 14 0 0 0 1.97E+06 3.15E+06 - - - 1.8975 0.9955 221125_WJC_METTL3_EV_vs_WT_F01.21842.21842.3 0.117 Sep-44 K.VDLLNQEIEFLK.V sp|P35908|K22E_HUMAN 1 1459.7922 30.95 9188 21842 3 1459.791422 487.6047 "Keratin, type II cytoskeletal 2 epidermal OS=Homo sapiens OX=9606 GN=KRT2 PE=1 SV=2" 4.14 3935.2 - 381811 - - - -0.5645 - 1.856 0.184 - 131.9 1 2 0 -0.0008 12 0 0 0 3.31E+07 1.07E+06 - - - 2.3054 1 221125_WJC_METTL3_EV_vs_WT_F01.21844.21844.2 3.52E-06 14/30 L.SLGLETAGGVMTALIK[136.11].R "sp|P0DMV8|HS71A_HUMAN,sp|P34931|HS71L_HUMAN,sp|P0DMV9|HS71B_HUMAN,tr|Q53FA3|Q53FA3_HUMAN,tr|V9GZ37|V9GZ37_HUMAN,tr|A0A0G2JIW1|A0A0G2JIW1_HUMAN" 6 1567.8735 -1 9190 21844 2 1567.873227 784.944 Heat shock 70 kDa protein 1A OS=Homo sapiens OX=9606 GN=HSPA1A PE=1 SV=1 5.72 3935.4 - 9.18E+06 - - - -0.1614 - 2.998 0.609 - 560.7 1 1 0 -0.0003 16 0 0 0 0.00E+00 0.00E+00 - - - 6.2383 0.9997 221125_WJC_METTL3_EV_vs_WT_F01.21845.21845.2 0.00213 20-Oct K.GFLSGLLDNVK.Q "sp|O43615|TIM44_HUMAN,tr|M0R301|M0R301_HUMAN,tr|M0R124|M0R124_HUMAN,tr|M0QXU7|M0QXU7_HUMAN" 4 1161.6394 0.98 9191 21845 2 1161.640456 581.827 Mitochondrial import inner membrane translocase subunit TIM44 OS=Homo sapiens OX=9606 GN=TIMM44 PE=1 SV=2 5.84 3935.4 - 5.67E+06 - - - 0.9314 - 2.041 0.413 - 276.5 1 2 0 0.0011 11 0 0 0 1.24E+07 1.27E+07 - - - 4.0211 1 221125_WJC_METTL3_EV_vs_WT_F01.21846.21846.2 3.44E-06 15/24 R.NVIVLQTVLQEVR.N "sp|Q9Y2L1|RRP44_HUMAN,tr|F2Z2C0|F2Z2C0_HUMAN" 2 1509.8879 1.55 9192 21846 2 1509.888478 755.9512 Exosome complex exonuclease RRP44 OS=Homo sapiens OX=9606 GN=DIS3 PE=1 SV=2 6 3935.5 - 3.70E+06 - - - 0.3974 - 3.017 0.588 - 872.6 1 2 0 0.0006 13 0 0 0 1.88E+07 1.22E+07 - - - 6.2179 1 221125_WJC_METTL3_EV_vs_WT_F01.21847.21847.2 0.00718 15/24 R.NVIVLQTVLQEVR[166.11].N "sp|Q9Y2L1|RRP44_HUMAN,tr|F2Z2C0|F2Z2C0_HUMAN" 2 1519.8961 1.55 9193 21847 2 1519.896917 760.9554 Exosome complex exonuclease RRP44 OS=Homo sapiens OX=9606 GN=DIS3 PE=1 SV=2 6 3935.6 - 2.38E+06 - - - 0.506 - 3.003 0.526 - 948.7 1 2 0 0.0008 13 0 0 0 1.88E+07 1.22E+07 - - - 5.748 1 221125_WJC_METTL3_EV_vs_WT_F01.21848.21848.2 1.56E-08 15/28 K.LLGQFTLIGIPPAPR[166.11].G "sp|P38646|GRP75_HUMAN,tr|A0A7I2V2S7|A0A7I2V2S7_HUMAN,tr|A0A7I2V2G2|A0A7I2V2G2_HUMAN,tr|H0Y8S0|H0Y8S0_HUMAN,tr|A0A7I2V3F7|A0A7I2V3F7_HUMAN,tr|A0A7I2YQB2|A0A7I2YQB2_HUMAN,tr|D6RCD7|D6RCD7_HUMAN" 7 1601.9533 0.38 9194 21848 2 1601.952194 801.9839 "Stress-70 protein, mitochondrial OS=Homo sapiens OX=9606 GN=HSPA9 PE=1 SV=2" 9.75 3935.6 - 2.24E+06 - - - -0.6711 - 2.99 0.644 - 603.7 1 2 0 -0.0011 15 0 0 0 9.37E+06 2.49E+07 - - - 6.49 0.9998 221125_WJC_METTL3_EV_vs_WT_F01.21849.21849.2 0.000344 20-Sep K.DFAPVIVEAFK.H "sp|Q96P16|RPR1A_HUMAN,tr|A0A0C4DGQ6|A0A0C4DGQ6_HUMAN" 2 1234.6598 1.49 9195 21849 2 1234.66091 618.3372 Regulation of nuclear pre-mRNA domain-containing protein 1A OS=Homo sapiens OX=9606 GN=RPRD1A PE=1 SV=1 4.37 3935.7 - 2.19E+06 - - - 0.9193 - 1.93 0.494 - 201.7 1 2 0 0.0011 11 0 0 0 1.43E+07 9.57E+06 - - - 4.4681 1 221125_WJC_METTL3_EV_vs_WT_F01.21850.21850.3 7.43E-07 17/56 K.LLGQFTLIGIPPAPR[166.11].G "sp|P38646|GRP75_HUMAN,tr|A0A7I2V2S7|A0A7I2V2S7_HUMAN,tr|A0A7I2V2G2|A0A7I2V2G2_HUMAN,tr|H0Y8S0|H0Y8S0_HUMAN,tr|A0A7I2V3F7|A0A7I2V3F7_HUMAN,tr|A0A7I2YQB2|A0A7I2YQB2_HUMAN,tr|D6RCD7|D6RCD7_HUMAN" 7 1601.9533 0.41 9196 21850 3 1601.954619 534.9917 "Stress-70 protein, mitochondrial OS=Homo sapiens OX=9606 GN=HSPA9 PE=1 SV=2" 9.75 3935.7 - 1.66E+06 - - - 0.8427 - 3.015 0.576 - 331 1 2 0 0.0014 15 0 0 0 1.01E+07 2.44E+07 - - - 7.8412 0.9998 221125_WJC_METTL3_EV_vs_WT_F01.21852.21852.2 0.00454 20-Nov K.DFAPVIVEAFK[136.11].H "sp|Q96P16|RPR1A_HUMAN,tr|A0A0C4DGQ6|A0A0C4DGQ6_HUMAN" 2 1242.674 1.49 9198 21852 2 1242.673869 622.3443 Regulation of nuclear pre-mRNA domain-containing protein 1A OS=Homo sapiens OX=9606 GN=RPRD1A PE=1 SV=1 4.37 3935.9 - 1.39E+06 - - - -0.0853 - 2.007 0.389 - 365.2 1 2 0 -0.0001 11 0 0 0 1.43E+07 9.57E+06 - - - 3.7987 1 221125_WJC_METTL3_EV_vs_WT_F01.21855.21855.3 4.71E-06 16/48 R.NVIVLQTVLQEVR.N "sp|Q9Y2L1|RRP44_HUMAN,tr|F2Z2C0|F2Z2C0_HUMAN" 2 1509.8879 -1 9201 21855 3 1509.887753 504.3032 Exosome complex exonuclease RRP44 OS=Homo sapiens OX=9606 GN=DIS3 PE=1 SV=2 6 3936.2 - 898357 - - - -0.0828 - 2.895 0.568 - 432.1 1 2 0 -0.0001 13 0 0 0 0.00E+00 0.00E+00 - - - 7.7547 0.9999 221125_WJC_METTL3_EV_vs_WT_F01.21859.21859.2 1.82E-06 20-Nov K.GYEEWLLNEIR.R "sp|O43707|ACTN4_HUMAN,sp|P35609|ACTN2_HUMAN,sp|P12814|ACTN1_HUMAN,tr|A0A804HK61|A0A804HK61_HUMAN,tr|A0A804HJU8|A0A804HJU8_HUMAN,tr|A0A804HIN7|A0A804HIN7_HUMAN,tr|A0A494C060|A0A494C060_HUMAN,tr|H9KV75|H9KV75_HUMAN,tr|A0A804HLF4|A0A804HLF4_HUMAN,tr|A0A7I2V4Y4|A0A7I2V4Y4_HUMAN,tr|A0A804HII9|A0A804HII9_HUMAN,tr|A0A804HL31|A0A804HL31_HUMAN,tr|A0A494C1A0|A0A494C1A0_HUMAN,tr|F5GXS2|F5GXS2_HUMAN,tr|A0A804HI95|A0A804HI95_HUMAN,tr|A0A804HKE2|A0A804HKE2_HUMAN,tr|A0A804HLD0|A0A804HLD0_HUMAN,tr|H7C144|H7C144_HUMAN" 18 1420.6987 1.59 9205 21859 2 1420.697753 711.3566 Alpha-actinin-4 OS=Homo sapiens OX=9606 GN=ACTN4 PE=1 SV=2 4.25 3936.7 - 440047 - - - -0.6525 - 2.459 0.541 - 556.9 1 2 0 -0.0009 11 0 0 0 9.82E+05 6.16E+05 - - - 5.4706 0.9961 221125_WJC_METTL3_EV_vs_WT_F01.21860.21860.2 0.48 26-Jul K.ASVVTLPVYLNFTR.A "sp|Q14204|DYHC1_HUMAN,tr|A0A2R8Y706|A0A2R8Y706_HUMAN" 2 1578.877 -1 9206 21860 2 1578.877412 790.4458 Cytoplasmic dynein 1 heavy chain 1 OS=Homo sapiens OX=9606 GN=DYNC1H1 PE=1 SV=5 8.79 3936.8 - 406177 - - - 0.2742 - 1.285 0.222 - 93.1 1 2 0 0.0004 14 0 0 0 0.00E+00 0.00E+00 - - - 1.3098 1 221125_WJC_METTL3_EV_vs_WT_F01.21861.21861.2 1.38E-14 16/26 R.FGDPEC[160.03]QVILPLLK[136.11].S sp|P22102|PUR2_HUMAN 1 1635.8786 0.62 9207 21861 2 1635.882291 818.9466 Trifunctional purine biosynthetic protein adenosine-3 OS=Homo sapiens OX=9606 GN=GART PE=1 SV=1 4.37 3937 - 361012 - - - 2.2777 - 3.164 0.687 - 727.1 1 2 0 0.0037 14 0 0 0 1.67E+06 2.71E+06 - - - 7.0045 1 221125_WJC_METTL3_EV_vs_WT_F01.21863.21863.2 1.65E-09 13/26 R.FGDPEC[160.03]QVILPLLK.S sp|P22102|PUR2_HUMAN 1 1627.8644 0.61 9208 21863 2 1627.865296 814.9395 Trifunctional purine biosynthetic protein adenosine-3 OS=Homo sapiens OX=9606 GN=GART PE=1 SV=1 4.37 3937.3 - 372305 - - - 0.5719 - 2.839 0.601 - 432.9 1 2 0 0.0009 14 0 0 0 1.53E+06 2.51E+06 - - - 6.0982 0.9999 221125_WJC_METTL3_EV_vs_WT_F01.21864.21864.2 3.50E-09 14/28 R.DISEASVFDAYVLPK[136.11].L sp|P62854|RS26_HUMAN 1 1660.844 -1 9209 21864 2 1660.843441 831.4293 40S ribosomal protein S26 OS=Homo sapiens OX=9606 GN=RPS26 PE=1 SV=3 4.03 3937.5 - 560206 - - - -0.3089 - 2.699 0.538 - 501.8 1 2 0 -0.0005 15 0 0 0 0.00E+00 0.00E+00 - - - 5.4556 0.9997 221125_WJC_METTL3_EV_vs_WT_F01.21867.21867.3 5.42E-05 14/56 K.LLGQFTLIGIPPAPR.G "sp|P38646|GRP75_HUMAN,tr|A0A7I2V2S7|A0A7I2V2S7_HUMAN,tr|A0A7I2V2G2|A0A7I2V2G2_HUMAN,tr|H0Y8S0|H0Y8S0_HUMAN,tr|A0A7I2V3F7|A0A7I2V3F7_HUMAN,tr|A0A7I2YQB2|A0A7I2YQB2_HUMAN,tr|D6RCD7|D6RCD7_HUMAN" 7 1591.945 0.41 9212 21867 3 1591.945409 531.6556 "Stress-70 protein, mitochondrial OS=Homo sapiens OX=9606 GN=HSPA9 PE=1 SV=2" 9.75 3937.7 - 1.35E+06 - - - 0.2575 - 2.163 0.332 - 229.2 1 2 0 0.0004 15 0 0 0 9.16E+06 2.22E+07 - - - 4.2545 0.9999 221125_WJC_METTL3_EV_vs_WT_F01.21871.21871.2 1.15E-06 13/22 R.ILTMDGLIEDIK[136.11].H sp|P82921|RT21_HUMAN 1 1367.7462 -1 9216 21871 2 1367.746902 684.8804 "28S ribosomal protein S21, mitochondrial OS=Homo sapiens OX=9606 GN=MRPS21 PE=1 SV=3" 4.03 3938.1 - 728127 - - - 0.5469 - 2.595 0.499 - 504.7 1 2 0 0.0007 12 0 0 0 0.00E+00 0.00E+00 - - - 5.2354 1 221125_WJC_METTL3_EV_vs_WT_F01.21872.21872.2 0.000152 17/24 R.VNILEVASGAVLR[166.11].S sp|Q12788|TBL3_HUMAN 1 1349.7906 -1 9217 21872 2 1349.790467 675.9026 Transducin beta-like protein 3 OS=Homo sapiens OX=9606 GN=TBL3 PE=1 SV=2 5.97 3938.2 - 662516 - - - -0.1134 - 3.074 0.515 - 970.1 1 2 0 -0.0002 13 0 0 0 0.00E+00 0.00E+00 - - - 5.7269 0.9994 221125_WJC_METTL3_EV_vs_WT_F01.21873.21873.2 0.0145 22-Sep R.VALILQNVDLPN.- "sp|Q04446|GLGB_HUMAN,tr|E9PGM4|E9PGM4_HUMAN" 2 1307.7449 - 9218 21873 2 1307.74547 654.8797 "1,4-alpha-glucan-branching enzyme OS=Homo sapiens OX=9606 GN=GBE1 PE=1 SV=3" 3.8 3938.4 - 652968 - - - 0.4343 - 1.712 0.329 - 160.8 1 2 0 0.0006 12 0 0 0 - - - - - 2.8855 0.9999 221125_WJC_METTL3_EV_vs_WT_F01.21875.21875.2 1.69E-06 Dec-32 R.AIGLSPMSFPTADLTLK[136.11].M "sp|Q5JSZ5|PRC2B_HUMAN,tr|A0A804HKC3|A0A804HKC3_HUMAN,tr|A0A804HJR4|A0A804HJR4_HUMAN" 3 1768.9525 -1 9220 21875 2 1768.950348 885.4835 Protein PRRC2B OS=Homo sapiens OX=9606 GN=PRRC2B PE=1 SV=2 5.88 3938.6 - 495435 - - - -1.1928 - 2.458 0.512 - 376 1 2 0 -0.0021 17 0 0 0 0.00E+00 0.00E+00 - - - 5.0331 0.9875 221125_WJC_METTL3_EV_vs_WT_F01.21884.21884.2 4.40E-05 18-Jul R.LFPPQWIC[160.03]C[160.03]D.L sp|Q86U44|MTA70_HUMAN 1 1334.5788 - 9228 21884 2 1334.578081 668.2967 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 4.3 3939.8 - 765817 - - - -0.5125 - 1.415 0.547 - 172.5 1 1 0 -0.0007 10 0 0 0 - - - - - 4.0499 0.9998 221125_WJC_METTL3_EV_vs_WT_F01.21891.21891.2 2.28E-05 22-Dec R.ANLGVFSVFAPR.G "sp|A6NHR9|SMHD1_HUMAN,tr|J3KTL8|J3KTL8_HUMAN" 2 1276.6928 1.38 9235 21891 2 1276.694516 639.3537 Structural maintenance of chromosomes flexible hinge domain-containing protein 1 OS=Homo sapiens OX=9606 GN=SMCHD1 PE=1 SV=2 9.79 3940.5 - 504588 - - - 1.3386 - 2.644 0.452 - 625.2 1 2 0 0.0017 12 0 0 0 2.53E+06 1.83E+06 - - - 4.9372 0.9997 221125_WJC_METTL3_EV_vs_WT_F01.21894.21894.2 0.000685 20-Nov K.FVSISDLLVPK.D sp|P50395|GDIB_HUMAN 1 1216.7067 -1 9238 21894 2 1216.706113 609.3606 Rab GDP dissociation inhibitor beta OS=Homo sapiens OX=9606 GN=GDI2 PE=1 SV=2 5.84 3940.9 - 455313 - - - -0.503 - 1.676 0.454 - 278.7 1 2 0 -0.0006 11 0 0 0 0.00E+00 0.00E+00 - - - 3.7911 0.9991 221125_WJC_METTL3_EV_vs_WT_F01.21895.21895.2 0.00888 28-Oct R.ALVEVLGPYEPLLSR.V "sp|Q86VR2|RETR3_HUMAN,tr|K7EMF4|K7EMF4_HUMAN,tr|K7ELM8|K7ELM8_HUMAN,tr|K7EJ34|K7EJ34_HUMAN,tr|K7ENF4|K7ENF4_HUMAN,tr|K7ENZ6|K7ENZ6_HUMAN" 6 1654.9294 -1 9239 21895 2 1654.929487 828.472 Reticulophagy regulator 3 OS=Homo sapiens OX=9606 GN=RETREG3 PE=1 SV=1 4.53 3941 - 418156 - - - 0.0477 - 2.096 0.215 - 322.3 1 2 0 0.0001 15 0 0 0 0.00E+00 0.00E+00 - - - 2.4484 0.997 221125_WJC_METTL3_EV_vs_WT_F01.21897.21897.3 0.147 Aug-48 R.VNILEVASGAVLR[166.11].S sp|Q12788|TBL3_HUMAN 1 1349.7906 -1 9241 21897 3 1349.790214 450.9375 Transducin beta-like protein 3 OS=Homo sapiens OX=9606 GN=TBL3 PE=1 SV=2 5.97 3941.3 - 411678 - - - -0.3008 - 1.965 0.196 - 45.4 1 2 0 -0.0004 13 0 0 0 0.00E+00 0.00E+00 - - - 2.5566 0.9999 221125_WJC_METTL3_EV_vs_WT_F01.21898.21898.2 2.95E-05 24-Nov K.SIIGVIPYFPYSK[136.11].Q "sp|O60256|KPRB_HUMAN,tr|C9JJS3|C9JJS3_HUMAN,tr|C9JDU5|C9JDU5_HUMAN,tr|E7EPA1|E7EPA1_HUMAN,tr|E7EW35|E7EW35_HUMAN,tr|C9JDH0|C9JDH0_HUMAN,tr|C9K0K7|C9K0K7_HUMAN" 7 1490.8265 -1 9242 21898 2 1490.827108 746.4205 Phosphoribosyl pyrophosphate synthase-associated protein 2 OS=Homo sapiens OX=9606 GN=PRPSAP2 PE=1 SV=1 8.22 3941.4 - 393015 - - - 0.4394 - 2.343 0.527 - 359.6 1 2 0 0.0007 13 0 0 0 0.00E+00 0.00E+00 - - - 5.1184 0.9868 221125_WJC_METTL3_EV_vs_WT_F01.21902.21902.2 1.93E-07 18/26 K.LTVQEEQIVELIEK.L "sp|P52732|KIF11_HUMAN,tr|A0A7I2YQY4|A0A7I2YQY4_HUMAN,tr|A0A7I2V3A9|A0A7I2V3A9_HUMAN,tr|A0A7I2V3V3|A0A7I2V3V3_HUMAN" 4 1669.9138 -1 9246 21902 2 1669.8999 835.9642 Kinesin-like protein KIF11 OS=Homo sapiens OX=9606 GN=KIF11 PE=1 SV=2 4.09 3941.9 - 301139 - - - -8.3346 - 3.181 0.472 - 1484.9 1 2 0 -0.0139 14 0 0 0 0.00E+00 0.00E+00 - - - 5.4267 0.9996 221125_WJC_METTL3_EV_vs_WT_F01.21907.21907.2 0.00274 20-Oct K.LILPELGPVFK[136.11].Q "sp|Q6P3W7|SCYL2_HUMAN,tr|H0YIK6|H0YIK6_HUMAN,tr|F8VSC5|F8VSC5_HUMAN,tr|A0A0U1RQQ9|A0A0U1RQQ9_HUMAN" 4 1232.7624 1.82 9250 21907 2 1232.764412 617.3885 SCY1-like protein 2 OS=Homo sapiens OX=9606 GN=SCYL2 PE=1 SV=1 6 3942.5 - 2.16E+06 - - - 1.6354 - 1.949 0.443 - 337.2 1 2 0 0.002 11 0 0 0 1.77E+07 9.73E+06 - - - 4.1176 0.9999 221125_WJC_METTL3_EV_vs_WT_F01.21909.21909.2 1.63E-05 22-Nov R.GISLANWMC[160.03]LAK.W "sp|P61626|LYSC_HUMAN,tr|A0A0B4J259|A0A0B4J259_HUMAN,tr|F8VV32|F8VV32_HUMAN" 3 1362.6788 -1 9252 21909 2 1362.678711 682.3467 Lysozyme C OS=Homo sapiens OX=9606 GN=LYZ PE=1 SV=1 8.22 3942.6 - 1.54E+06 - - - -0.0749 - 2.233 0.455 - 429.7 1 2 0 -0.0001 12 0 0 0 0.00E+00 0.00E+00 - - - 4.5153 0.9999 221125_WJC_METTL3_EV_vs_WT_F01.21910.21910.3 0.000529 13/52 K.LTVQEEQIVELIEK.L "sp|P52732|KIF11_HUMAN,tr|A0A7I2YQY4|A0A7I2YQY4_HUMAN,tr|A0A7I2V3A9|A0A7I2V3A9_HUMAN,tr|A0A7I2V3V3|A0A7I2V3V3_HUMAN" 4 1669.9138 -1 9253 21910 3 1669.916645 557.6452 Kinesin-like protein KIF11 OS=Homo sapiens OX=9606 GN=KIF11 PE=1 SV=2 4.09 3942.7 - 1.54E+06 - - - 1.6929 - 2.408 0.395 - 176.9 1 2 0 0.0028 14 0 0 0 0.00E+00 0.00E+00 - - - 5.2785 1 221125_WJC_METTL3_EV_vs_WT_F01.21911.21911.2 5.68E-07 15/28 K.LLGQFTLIGIPPAPR.G "sp|P38646|GRP75_HUMAN,tr|A0A7I2V2S7|A0A7I2V2S7_HUMAN,tr|A0A7I2V2G2|A0A7I2V2G2_HUMAN,tr|H0Y8S0|H0Y8S0_HUMAN,tr|A0A7I2V3F7|A0A7I2V3F7_HUMAN,tr|A0A7I2YQB2|A0A7I2YQB2_HUMAN,tr|D6RCD7|D6RCD7_HUMAN" 7 1591.945 0.38 9254 21911 2 1591.947247 796.9798 "Stress-70 protein, mitochondrial OS=Homo sapiens OX=9606 GN=HSPA9 PE=1 SV=2" 9.75 3942.8 - 1.05E+06 - - - 1.4121 - 2.881 0.615 - 550.9 1 2 0 0.0022 15 0 0 0 9.37E+06 2.49E+07 - - - 6.1842 0.9999 221125_WJC_METTL3_EV_vs_WT_F01.21913.21913.2 2.56E-05 22-Oct K.GVNSYPSLFIFR[166.11].S "sp|Q8IXB1|DJC10_HUMAN,tr|A0A7P0TB22|A0A7P0TB22_HUMAN,tr|A0A7P0Z4F2|A0A7P0Z4F2_HUMAN,tr|A0A7P0Z431|A0A7P0Z431_HUMAN,tr|A0A7P0TB97|A0A7P0TB97_HUMAN,tr|A0A7P0TAQ9|A0A7P0TAQ9_HUMAN,tr|E7EP04|E7EP04_HUMAN,tr|A0A7P0T9B7|A0A7P0T9B7_HUMAN,tr|A0A494C1G5|A0A494C1G5_HUMAN,tr|A0A7P0TB83|A0A7P0TB83_HUMAN" 10 1408.7379 -1 9256 21913 2 1408.739395 705.3762 DnaJ homolog subfamily C member 10 OS=Homo sapiens OX=9606 GN=DNAJC10 PE=1 SV=2 8.75 3943.1 - 851326 - - - 1.0925 - 2.451 0.522 - 189.7 1 2 0 0.0015 12 0 0 0 0.00E+00 0.00E+00 - - - 5.2548 0.9998 221125_WJC_METTL3_EV_vs_WT_F01.21916.21916.2 1.19E-05 22-Oct K.GVNSYPSLFIFR.S "sp|Q8IXB1|DJC10_HUMAN,tr|A0A7P0TB22|A0A7P0TB22_HUMAN,tr|A0A7P0Z4F2|A0A7P0Z4F2_HUMAN,tr|A0A7P0Z431|A0A7P0Z431_HUMAN,tr|A0A7P0TB97|A0A7P0TB97_HUMAN,tr|A0A7P0TAQ9|A0A7P0TAQ9_HUMAN,tr|E7EP04|E7EP04_HUMAN,tr|A0A7P0T9B7|A0A7P0T9B7_HUMAN,tr|A0A494C1G5|A0A494C1G5_HUMAN,tr|A0A7P0TB83|A0A7P0TB83_HUMAN" 10 1398.7296 1.27 9259 21916 2 1398.731857 700.3721 DnaJ homolog subfamily C member 10 OS=Homo sapiens OX=9606 GN=DNAJC10 PE=1 SV=2 8.75 3943.4 - 705646 - - - 1.6236 - 2.232 0.541 - 206.5 1 2 0 0.0023 12 0 0 0 2.91E+06 2.29E+06 - - - 5.1487 0.9997 221125_WJC_METTL3_EV_vs_WT_F01.21919.21919.2 0.000289 14/28 K.VVPTLPEGLPVLLEK[136.11].R "sp|Q6ZU65|UBN2_HUMAN,tr|H7C4P8|H7C4P8_HUMAN" 2 1610.9738 7.57 9262 21919 2 1610.974158 806.4942 Ubinuclein-2 OS=Homo sapiens OX=9606 GN=UBN2 PE=1 SV=2 4.53 3943.8 - 682022 - - - 0.1937 - 1.849 0.42 - 468.2 1 2 0 0.0003 15 0 0 0 2.30E+07 3.04E+06 - - - 3.6542 0.9995 221125_WJC_METTL3_EV_vs_WT_F01.21920.21920.2 0.00395 16-Sep R.YLDVSILGK[136.11].F sp|Q86U44|MTA70_HUMAN 1 1014.5841 0.38 9263 21920 2 1014.58656 508.2993 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 5.83 3943.9 - 660405 - - - 2.4266 - 1.896 0.453 - 203.4 1 2 0 0.0025 9 0 0 0 6.11E+06 1.59E+07 - - - 4.2369 0.9975 221125_WJC_METTL3_EV_vs_WT_F01.21922.21922.2 3.68 22-Jun K.IVILPDYLEIAR[166.11].D sp|P45974|UBP5_HUMAN 1 1423.8314 -1 9265 21922 2 1423.832798 712.923 Ubiquitin carboxyl-terminal hydrolase 5 OS=Homo sapiens OX=9606 GN=USP5 PE=1 SV=2 4.37 3944.2 - 573802 - - - 0.9664 - 1.497 0.234 - 122.7 1 2 0 0.0014 12 0 0 0 0.00E+00 0.00E+00 - - - 1.8305 0.9999 221125_WJC_METTL3_EV_vs_WT_F01.21924.21924.3 0.0045 Dec-48 R.IESILMSLPLTAR.W "sp|P36551|HEM6_HUMAN,tr|H0YA22|H0YA22_HUMAN" 2 1442.8167 -1 9267 21924 3 1442.819269 481.9462 "Oxygen-dependent coproporphyrinogen-III oxidase, mitochondrial OS=Homo sapiens OX=9606 GN=CPOX PE=1 SV=3" 6 3944.5 - 519024 - - - 1.7896 - 2.613 0.385 - 156.8 1 2 0 0.0026 13 0 0 0 0.00E+00 0.00E+00 - - - 5.4358 0.9999 221125_WJC_METTL3_EV_vs_WT_F01.21927.21927.2 3.32E-07 13/24 K.LGAGTFQLDQWLR[166.11].A sp|P50219|MNX1_HUMAN 1 1513.7917 -1 9269 21927 2 1513.792808 757.9031 Motor neuron and pancreas homeobox protein 1 OS=Homo sapiens OX=9606 GN=MNX1 PE=1 SV=3 5.84 3944.8 - 467017 - - - 0.7432 - 2.776 0.493 - 522.5 1 2 0 0.0011 13 0 0 0 0.00E+00 0.00E+00 - - - 5.3024 0.9997 221125_WJC_METTL3_EV_vs_WT_F01.21929.21929.2 0.0292 24-Nov R.IESILMSLPLTAR.W "sp|P36551|HEM6_HUMAN,tr|H0YA22|H0YA22_HUMAN" 2 1442.8167 -1 9271 21929 2 1442.817614 722.4156 "Oxygen-dependent coproporphyrinogen-III oxidase, mitochondrial OS=Homo sapiens OX=9606 GN=CPOX PE=1 SV=3" 6 3944.9 - 1.95E+06 - - - 0.6425 - 2.324 0.333 - 419.6 1 2 0 0.0009 13 0 0 0 0.00E+00 0.00E+00 - - - 3.6646 0.9999 221125_WJC_METTL3_EV_vs_WT_F01.21932.21932.2 0.00144 14/22 K.SLVALLVETQMK[136.11].K "sp|Q8TAQ2|SMRC2_HUMAN,sp|Q92922|SMRC1_HUMAN,tr|F8VXC8|F8VXC8_HUMAN" 3 1338.7672 0.3 9274 21932 2 1338.767538 670.3909 SWI\SNF complex subunit SMARCC2 OS=Homo sapiens OX=9606 GN=SMARCC2 PE=1 SV=1 5.72 3945.1 - 1.02E+06 - - - 0.2345 - 2.865 0.47 - 868.2 1 2 0 0.0003 12 0 0 0 6.17E+06 2.03E+07 - - - 5.2818 0.9999 221125_WJC_METTL3_EV_vs_WT_F01.21936.21936.3 6.90E-06 Dec-44 K.SLVALLVETQMK.K "sp|Q8TAQ2|SMRC2_HUMAN,sp|Q92922|SMRC1_HUMAN,tr|F8VXC8|F8VXC8_HUMAN" 3 1330.753 -1 9278 21936 3 1330.753897 444.5916 SWI\SNF complex subunit SMARCC2 OS=Homo sapiens OX=9606 GN=SMARCC2 PE=1 SV=1 5.72 3945.5 - 784250 - - - 0.656 - 2.472 0.429 - 226.5 1 2 0 0.0009 12 0 0 0 0.00E+00 0.00E+00 - - - 5.8313 0.9942 221125_WJC_METTL3_EV_vs_WT_F01.21937.21937.2 1.99E-05 14/24 K.FTVIRPFPGLVIN.N "sp|P78347|GTF2I_HUMAN,tr|A0A494C1K3|A0A494C1K3_HUMAN" 2 1471.8551 -1 9279 21937 2 1471.855925 736.9348 General transcription factor II-I OS=Homo sapiens OX=9606 GN=GTF2I PE=1 SV=2 9.75 3945.7 - 754008 - - - 0.5462 - 2.465 0.566 - 609.6 1 1 0 0.0008 13 0 0 0 0.00E+00 0.00E+00 - - - 5.5367 0.9971 221125_WJC_METTL3_EV_vs_WT_F01.21938.21938.3 0.0908 Sep-48 R.IESILMSLPLTAR[166.11].W "sp|P36551|HEM6_HUMAN,tr|H0YA22|H0YA22_HUMAN" 2 1452.825 1.15 9280 21938 3 1452.825853 485.2823 "Oxygen-dependent coproporphyrinogen-III oxidase, mitochondrial OS=Homo sapiens OX=9606 GN=CPOX PE=1 SV=3" 6 3945.8 - 677924 - - - 0.6167 - 1.981 0.196 - 111.6 1 2 0 0.0009 13 0 0 0 1.63E+06 1.42E+06 - - - 2.5784 0.9999 221125_WJC_METTL3_EV_vs_WT_F01.21939.21939.2 2.22E-06 26-Dec K.LDDIFEPVLIPEPK.L "sp|Q14008|CKAP5_HUMAN,tr|H0YEK7|H0YEK7_HUMAN,tr|H0YCF6|H0YCF6_HUMAN" 3 1623.876 1.83 9281 21939 2 1623.876552 812.9453 Cytoskeleton-associated protein 5 OS=Homo sapiens OX=9606 GN=CKAP5 PE=1 SV=3 3.92 3945.9 - 659266 - - - 0.3547 - 2.427 0.527 - 427.7 1 2 0 0.0006 14 0 0 0 2.51E+06 1.37E+06 - - - 5.1583 0.9997 221125_WJC_METTL3_EV_vs_WT_F01.21941.21941.2 1.48E-05 20-Dec K.NLVELAELELK.H "sp|Q9UNH7|SNX6_HUMAN,tr|A0A0A0MRI2|A0A0A0MRI2_HUMAN" 2 1269.718 -1 9283 21941 2 1269.71816 635.8663 Sorting nexin-6 OS=Homo sapiens OX=9606 GN=SNX6 PE=1 SV=1 4.25 3946.1 - 554166 - - - 0.1118 - 2.476 0.264 - 452.4 1 2 0 0.0001 11 0 0 0 0.00E+00 0.00E+00 - - - 3.4435 0.9691 221125_WJC_METTL3_EV_vs_WT_F01.21942.21942.2 0.286 26-Oct K.LFADAVQELLPQYK.E sp|P33993|MCM7_HUMAN 1 1633.8716 1.61 9284 21942 2 1633.878741 817.9431 DNA replication licensing factor MCM7 OS=Homo sapiens OX=9606 GN=MCM7 PE=1 SV=4 4.37 3946.3 - 527789 - - - 4.3957 - 1.345 0.249 - 156.3 1 2 0 0.0072 14 0 0 0 2.85E+06 1.76E+06 - - - 1.6216 0.9996 221125_WJC_METTL3_EV_vs_WT_F01.21944.21944.3 0.00184 Sep-44 K.SLVALLVETQMK[136.11].K "sp|Q8TAQ2|SMRC2_HUMAN,sp|Q92922|SMRC1_HUMAN,tr|F8VXC8|F8VXC8_HUMAN" 3 1338.7672 0.93 9286 21944 3 1338.76785 447.263 SWI\SNF complex subunit SMARCC2 OS=Homo sapiens OX=9606 GN=SMARCC2 PE=1 SV=1 5.72 3946.5 - 391791 - - - 0.4676 - 1.718 0.361 - 102.4 1 2 0 0.0006 12 0 0 0 1.56E+06 1.67E+06 - - - 4.0646 1 221125_WJC_METTL3_EV_vs_WT_F01.21948.21948.2 1.09E-07 28-Dec R.GFGFVTFMDQAGVDK.V sp|O43347|MSI1H_HUMAN 1 1617.7497 -1 9289 21948 2 1617.748542 809.8821 RNA-binding protein Musashi homolog 1 OS=Homo sapiens OX=9606 GN=MSI1 PE=1 SV=1 4.21 3947 - 1.37E+06 - - - -0.7337 - 2.831 0.649 - 449.8 1 2 0 -0.0012 15 0 0 0 0.00E+00 0.00E+00 - - - 6.3926 0.9992 221125_WJC_METTL3_EV_vs_WT_F01.21951.21951.2 0.00346 18-Jul K.EANNFLWPFK.L "sp|P18124|RL7_HUMAN,tr|A8MUD9|A8MUD9_HUMAN" 2 1264.6241 -1 9292 21951 2 1264.625072 633.3193 60S ribosomal protein L7 OS=Homo sapiens OX=9606 GN=RPL7 PE=1 SV=1 6.1 3947.2 - 1.53E+06 - - - 0.8018 - 1.666 0.307 - 143.2 1 2 0 0.001 10 0 0 0 0.00E+00 0.00E+00 - - - 2.7329 0.9985 221125_WJC_METTL3_EV_vs_WT_F01.21953.21953.2 0.0619 22-Dec K.SLVALLVETQMK.K "sp|Q8TAQ2|SMRC2_HUMAN,sp|Q92922|SMRC1_HUMAN,tr|F8VXC8|F8VXC8_HUMAN" 3 1330.753 -1 9294 21953 2 1330.755589 666.3838 SWI\SNF complex subunit SMARCC2 OS=Homo sapiens OX=9606 GN=SMARCC2 PE=1 SV=1 5.72 3947.4 - 999777 - - - 1.9275 - 1.648 0.32 - 269.4 1 2 0 0.0026 12 0 0 0 0.00E+00 0.00E+00 - - - 2.7181 1 221125_WJC_METTL3_EV_vs_WT_F01.21954.21954.2 9.91E-09 28-Nov R.GFGFVTFMDQAGVDK[136.11].V sp|O43347|MSI1H_HUMAN 1 1625.7639 -1 9295 21954 2 1625.764829 813.8892 RNA-binding protein Musashi homolog 1 OS=Homo sapiens OX=9606 GN=MSI1 PE=1 SV=1 4.21 3947.4 - 895884 - - - 0.5536 - 2.331 0.662 - 326.8 1 2 0 0.0009 15 0 0 0 0.00E+00 0.00E+00 - - - 6.0109 0.8087 221125_WJC_METTL3_EV_vs_WT_F01.21957.21957.2 0.805 24-Jul K.FTVIR[166.11]PFPGLVIN.N "sp|P78347|GTF2I_HUMAN,tr|A0A494C1K3|A0A494C1K3_HUMAN" 2 1481.8634 -1 9298 21957 2 1481.864082 741.939 General transcription factor II-I OS=Homo sapiens OX=9606 GN=GTF2I PE=1 SV=2 9.75 3947.8 - 608332 - - - 0.4663 - 1.538 0.161 - 170.7 1 1 0 0.0007 13 0 0 0 0.00E+00 0.00E+00 - - - 1.3348 0.999 221125_WJC_METTL3_EV_vs_WT_F01.21958.21958.2 0.0238 20-Aug K.NLVELAELELK[136.11].H "sp|Q9UNH7|SNX6_HUMAN,tr|A0A0A0MRI2|A0A0A0MRI2_HUMAN" 2 1277.7322 -1 9299 21958 2 1277.734389 639.8734 Sorting nexin-6 OS=Homo sapiens OX=9606 GN=SNX6 PE=1 SV=1 4.25 3947.9 - 494385 - - - 1.6991 - 1.786 0.317 - 180.8 1 2 0 0.0022 11 0 0 0 0.00E+00 0.00E+00 - - - 2.9507 0.9997 221125_WJC_METTL3_EV_vs_WT_F01.21961.21961.2 0.00148 16-Oct R.C[160.03]LLAYFLDK[136.11].S "sp|Q16875|F263_HUMAN,sp|O60825|F262_HUMAN,sp|P16118|F261_HUMAN,sp|Q16877|F264_HUMAN,tr|A0A1W2PR17|A0A1W2PR17_HUMAN,tr|I1Z9G3|I1Z9G3_HUMAN,tr|Q4VBA9|Q4VBA9_HUMAN,tr|Q66S35|Q66S35_HUMAN,tr|Q5W015|Q5W015_HUMAN,tr|F2Z2I2|F2Z2I2_HUMAN,tr|H0Y483|H0Y483_HUMAN,tr|Q5VX20|Q5VX20_HUMAN" 12 1149.5984 -1 9302 21961 2 1149.600215 575.8065 "6-phosphofructo-2-kinase\fructose-2,6-bisphosphatase 3 OS=Homo sapiens OX=9606 GN=PFKFB3 PE=1 SV=1" 5.83 3948.3 - 303749 - - - 1.6066 - 2.17 0.443 - 333.3 1 2 0 0.0018 9 0 0 0 0.00E+00 0.00E+00 - - - 4.5537 0.9993 221125_WJC_METTL3_EV_vs_WT_F01.21962.21962.2 0.00324 16-Nov K.AGLVELLLR[166.11].E "sp|Q13425|SNTB2_HUMAN,tr|A0A140TA73|A0A140TA73_HUMAN" 2 992.6258 -1 9303 21962 2 992.628703 497.3202 Beta-2-syntrophin OS=Homo sapiens OX=9606 GN=SNTB2 PE=1 SV=1 6.05 3948.5 - 272090 - - - 2.9387 - 2.447 0.366 - 408.3 1 2 0 0.0029 9 0 0 0 0.00E+00 0.00E+00 - - - 4.3322 0.9998 221125_WJC_METTL3_EV_vs_WT_F01.21977.21977.2 5.26E-06 24-Aug K.MFLGDAVDVFETR[166.11].R "sp|Q9BVL2|NUP58_HUMAN,tr|H7BYF2|H7BYF2_HUMAN,tr|Q5JRG1|Q5JRG1_HUMAN" 3 1508.7209 2.01 9317 21977 2 1508.721625 755.3677 Nucleoporin p58\p45 OS=Homo sapiens OX=9606 GN=NUP58 PE=1 SV=1 4.03 3950.3 - 493962 - - - 0.4898 - 2.086 0.477 - 143.5 1 2 0 0.0007 13 0 0 0 2.70E+06 1.34E+06 - - - 4.4509 0.9997 221125_WJC_METTL3_EV_vs_WT_F01.21981.21981.2 0.00272 26-Oct R.LVLPPPDPLDLPLR.A "sp|Q15477|SKIV2_HUMAN,tr|B4E0B4|B4E0B4_HUMAN,tr|F8WDE8|F8WDE8_HUMAN" 3 1553.9181 2.39 9321 21981 2 1553.918077 777.9663 Helicase SKI2W OS=Homo sapiens OX=9606 GN=SKIV2L PE=1 SV=3 4.21 3950.8 - 349783 - - - -0.0245 - 1.82 0.392 - 236.5 1 2 0 0 14 0 0 0 3.92E+06 1.64E+06 - - - 3.4391 0.9994 221125_WJC_METTL3_EV_vs_WT_F01.21982.21982.3 0.000432 Sep-40 K.VMVQPINLIFR.Y sp|P62304|RUXE_HUMAN 1 1328.7639 -1 9322 21982 3 1328.764839 443.9286 Small nuclear ribonucleoprotein E OS=Homo sapiens OX=9606 GN=SNRPE PE=1 SV=1 9.72 3950.9 - 347694 - - - 0.7345 - 1.393 0.374 - 93.5 1 2 0 0.001 11 0 0 0 0.00E+00 0.00E+00 - - - 3.6511 0.8667 221125_WJC_METTL3_EV_vs_WT_F01.21984.21984.2 4.18 18-May K.VVDLLAPYAK.G "sp|P06576|ATPB_HUMAN,tr|F8W079|F8W079_HUMAN,tr|H0YH81|H0YH81_HUMAN" 3 1087.6277 1.3 9324 21984 2 1087.629034 544.8211 "ATP synthase subunit beta, mitochondrial OS=Homo sapiens OX=9606 GN=ATP5F1B PE=1 SV=3" 5.81 3951.2 - 313757 - - - 1.1833 - 0.952 0.049 - 34.7 2 2 0 0.0013 10 0 0 0 1.27E+07 9.78E+06 - - - -0.8693 1 221125_WJC_METTL3_EV_vs_WT_F01.21986.21986.3 0.000258 25/60 K.INEAIVAVQAIIADPK.T sp|Q9Y224|RTRAF_HUMAN 1 1663.9509 -1 9326 21986 3 1663.952056 555.6576 "RNA transcription, translation and transport factor protein OS=Homo sapiens OX=9606 GN=RTRAF PE=1 SV=1" 4.37 3951.4 - 285608 - - - 0.7116 - 4.19 0.525 - 688.3 1 2 0 0.0012 16 0 0 0 0.00E+00 0.00E+00 - - - 8.069 0.9998 221125_WJC_METTL3_EV_vs_WT_F01.21987.21987.2 7.44E-05 22-Sep R.LFPPQWIC[160.03]C[160.03]DIR[166.11].Y sp|Q86U44|MTA70_HUMAN 1 1613.7722 0.001 9327 21987 2 1613.772423 807.8934 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 5.82 3951.6 - 282171 - - - 0.132 - 1.859 0.513 - 237.5 1 2 0 0.0002 12 0 0 0 0.00E+00 1.99E+06 - - - 4.4614 1 221125_WJC_METTL3_EV_vs_WT_F01.21993.21993.2 7.74E-11 18/34 K.LGGSLADSYLDEGFLLDK[136.11].K "sp|P78371|TCPB_HUMAN,tr|F8VQ14|F8VQ14_HUMAN,tr|F5GWF6|F5GWF6_HUMAN" 3 1919.9608 -1 9332 21993 2 1919.957967 960.9877 T-complex protein 1 subunit beta OS=Homo sapiens OX=9606 GN=CCT2 PE=1 SV=4 3.84 3952.1 - 3.80E+06 - - - -1.4625 - 3.677 0.669 - 1185.8 1 2 0 -0.0028 18 0 0 0 0.00E+00 0.00E+00 - - - 7.1826 1 221125_WJC_METTL3_EV_vs_WT_F01.21994.21994.3 5.50E-06 17/60 K.INEAIVAVQAIIADPK[136.11].T sp|Q9Y224|RTRAF_HUMAN 1 1671.9651 -1 9333 21994 3 1671.964459 558.329 "RNA transcription, translation and transport factor protein OS=Homo sapiens OX=9606 GN=RTRAF PE=1 SV=1" 4.37 3952.2 - 2.69E+06 - - - -0.3666 - 2.935 0.489 - 310 1 2 0 -0.0006 16 0 0 0 0.00E+00 0.00E+00 - - - 6.7544 1 221125_WJC_METTL3_EV_vs_WT_F01.21997.21997.2 6.88E-08 18/30 K.INEAIVAVQAIIADPK.T sp|Q9Y224|RTRAF_HUMAN 1 1663.9509 -1 9336 21997 2 1663.949498 832.9827 "RNA transcription, translation and transport factor protein OS=Homo sapiens OX=9606 GN=RTRAF PE=1 SV=1" 4.37 3952.4 - 1.96E+06 - - - -0.8257 - 3.579 0.545 - 1261.9 1 2 0 -0.0014 16 0 0 0 0.00E+00 0.00E+00 - - - 6.2008 1 221125_WJC_METTL3_EV_vs_WT_F01.21998.21998.2 6.15E-11 19/34 K.LGGSLADSYLDEGFLLDK.K "sp|P78371|TCPB_HUMAN,tr|F8VQ14|F8VQ14_HUMAN,tr|F5GWF6|F5GWF6_HUMAN" 3 1911.9466 -1 9337 21998 2 1911.944632 956.9806 T-complex protein 1 subunit beta OS=Homo sapiens OX=9606 GN=CCT2 PE=1 SV=4 3.84 3952.5 - 1.91E+06 - - - -1.0162 - 3.862 0.632 - 1501.2 1 2 0 -0.0019 18 0 0 0 0.00E+00 0.00E+00 - - - 7.0303 0.9989 221125_WJC_METTL3_EV_vs_WT_F01.22000.22000.2 1.54E-05 14-Oct R.C[160.03]FLSWLVK[136.11].L sp|Q92900|RENT1_HUMAN 1 1059.5667 -1 9339 22000 2 1059.567391 530.7906 Regulator of nonsense transcripts 1 OS=Homo sapiens OX=9606 GN=UPF1 PE=1 SV=2 8.22 3952.7 - 1.39E+06 - - - 0.6767 - 1.868 0.199 - 354 1 2 0 0.0007 8 0 0 0 0.00E+00 0.00E+00 - - - 2.3952 1 221125_WJC_METTL3_EV_vs_WT_F01.22001.22001.3 1.44E-07 15/68 K.LGGSLADSYLDEGFLLDK[136.11].K "sp|P78371|TCPB_HUMAN,tr|F8VQ14|F8VQ14_HUMAN,tr|F5GWF6|F5GWF6_HUMAN" 3 1919.9608 0.21 9340 22001 3 1919.95842 640.9942 T-complex protein 1 subunit beta OS=Homo sapiens OX=9606 GN=CCT2 PE=1 SV=4 3.84 3952.8 - 1.37E+06 - - - -1.2266 - 2.662 0.548 - 212.1 1 2 0 -0.0024 18 0 0 0 9.03E+05 4.22E+06 - - - 7.087 0.9976 221125_WJC_METTL3_EV_vs_WT_F01.22002.22002.2 0.0254 14-Sep R.C[160.03]FLSWLVK.L sp|Q92900|RENT1_HUMAN 1 1051.5525 -1 9341 22002 2 1051.552837 526.7835 Regulator of nonsense transcripts 1 OS=Homo sapiens OX=9606 GN=UPF1 PE=1 SV=2 8.22 3952.9 - 1.16E+06 - - - 0.3452 - 1.388 0.226 - 273.3 1 2 0 0.0004 8 0 0 0 0.00E+00 0.00E+00 - - - 1.6989 0.9993 221125_WJC_METTL3_EV_vs_WT_F01.22015.22015.2 0.0426 16-Sep R.FLILPDMLK[136.11].N sp|P62318|SMD3_HUMAN 1 1096.6446 1.52 9353 22015 2 1096.642752 549.3296 Small nuclear ribonucleoprotein Sm D3 OS=Homo sapiens OX=9606 GN=SNRPD3 PE=1 SV=1 5.84 3954.2 - 4.60E+06 - - - -1.6751 - 1.69 0.364 - 274.4 1 2 0 -0.0018 9 0 0 0 2.45E+07 1.61E+07 - - - 3.247 0.9997 221125_WJC_METTL3_EV_vs_WT_F01.22017.22017.2 9.75E-05 20-Dec K.LSAMMGAVAEK[136.11].K "sp|Q86U44|MTA70_HUMAN,tr|F5H6D8|F5H6D8_HUMAN,tr|H0YFV6|H0YFV6_HUMAN,tr|B4DTN4|B4DTN4_HUMAN" 4 1114.5606 -1 9355 22017 2 1114.558176 558.2876 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 6 3954.3 - 2.14E+06 - - - -2.1766 - 2.406 0.479 - 431.5 1 2 0 -0.0024 11 0 0 0 0.00E+00 0.00E+00 - - - 4.9532 0.9272 221125_WJC_METTL3_EV_vs_WT_F01.22018.22018.2 1.19 20-Jul K.DLTNVQNLQK[136.11]K[136.11].H "sp|Q13813|SPTN1_HUMAN,tr|A0A0D9SF54|A0A0D9SF54_HUMAN,tr|A0A0D9SGF6|A0A0D9SGF6_HUMAN" 3 1315.7431 -1 9356 22018 2 1315.740069 658.8788 "Spectrin alpha chain, non-erythrocytic 1 OS=Homo sapiens OX=9606 GN=SPTAN1 PE=1 SV=3" 8.59 3954.4 - 1.79E+06 - - - -2.2763 - 0.832 0.186 - 57.2 1 2 0 -0.003 11 0 0 0 0.00E+00 0.00E+00 - - - -0.0837 0.9998 221125_WJC_METTL3_EV_vs_WT_F01.22020.22020.2 2.30E-05 26-Dec K.LSLEFGDPASSLFR[166.11].W "sp|Q6L8Q7|PDE12_HUMAN,tr|F6T1Q0|F6T1Q0_HUMAN" 2 1547.7859 0.83 9358 22020 2 1547.782904 774.9002 "2',5'-phosphodiesterase 12 OS=Homo sapiens OX=9606 GN=PDE12 PE=1 SV=2" 4.37 3954.5 - 1.43E+06 - - - -1.9544 - 2.26 0.55 - 335.3 1 2 0 -0.003 14 0 0 0 3.47E+06 4.18E+06 - - - 5.1485 0.9998 221125_WJC_METTL3_EV_vs_WT_F01.22022.22022.2 0.00663 14/26 K.LSLEFGDPASSLFR.W "sp|Q6L8Q7|PDE12_HUMAN,tr|F6T1Q0|F6T1Q0_HUMAN" 2 1537.7777 -1 9360 22022 2 1537.775294 769.8961 "2',5'-phosphodiesterase 12 OS=Homo sapiens OX=9606 GN=PDE12 PE=1 SV=2" 4.37 3954.7 - 1.09E+06 - - - -1.5379 - 2.81 0.442 - 426.8 1 2 0 -0.0024 14 0 0 0 0.00E+00 0.00E+00 - - - 4.8976 0.9997 221125_WJC_METTL3_EV_vs_WT_F01.22023.22023.2 8.18E-06 20-Oct R.FYLPILVPSAK.K "sp|Q68CQ7|GL8D1_HUMAN,tr|C9J880|C9J880_HUMAN" 2 1246.7325 -1 9361 22023 2 1246.730614 624.3735 Glycosyltransferase 8 domain-containing protein 1 OS=Homo sapiens OX=9606 GN=GLT8D1 PE=1 SV=2 8.59 3954.9 - 858184 - - - -1.5497 - 1.837 0.486 - 335.8 1 2 0 -0.0019 11 0 0 0 0.00E+00 0.00E+00 - - - 4.2751 0.9997 221125_WJC_METTL3_EV_vs_WT_F01.22024.22024.2 0.000321 30-Sep K.EIPAWVPFDPAAQITK.Q "sp|P25311|ZA2G_HUMAN,tr|C9JEV0|C9JEV0_HUMAN" 2 1781.9352 999 9362 22024 2 1781.934647 891.9749 Zinc-alpha-2-glycoprotein OS=Homo sapiens OX=9606 GN=AZGP1 PE=1 SV=2 4.37 3955 - 755251 - - - -0.3227 - 1.466 0.488 - 152 1 2 0 -0.0006 16 0 0 0 2.11E+06 0.00E+00 - - - 3.5857 0.9999 221125_WJC_METTL3_EV_vs_WT_F01.22025.22025.2 3.57E-06 30-Aug K.ITISPLQELTLYNPER.T sp|O00425|IF2B3_HUMAN 1 1886.0149 -1 9363 22025 2 1886.015617 944.0147 Insulin-like growth factor 2 mRNA-binding protein 3 OS=Homo sapiens OX=9606 GN=IGF2BP3 PE=1 SV=2 4.53 3955.1 - 684882 - - - 0.3648 - 2.345 0.552 - 156 1 2 0 0.0007 16 0 0 0 0.00E+00 0.00E+00 - - - 5.2132 0.9948 221125_WJC_METTL3_EV_vs_WT_F01.22029.22029.2 0.0614 16-Jul R.TFAFSFWPK.D sp|Q9P2D1|CHD7_HUMAN 1 1129.5597 1.92 9367 22029 2 1129.557291 565.7871 Chromodomain-helicase-DNA-binding protein 7 OS=Homo sapiens OX=9606 GN=CHD7 PE=1 SV=3 8.41 3955.6 - 457620 - - - -2.1035 - 1.365 0.239 - 147.3 1 2 0 -0.0024 9 0 0 0 2.02E+06 1.05E+06 - - - 1.7057 0.9996 221125_WJC_METTL3_EV_vs_WT_F01.22036.22036.2 0.00092 14/24 R.ALTLGALTLPLAR.L sp|Q9BSJ8|ESYT1_HUMAN 1 1308.8129 -1 9373 22036 2 1308.81018 655.4137 Extended synaptotagmin-1 OS=Homo sapiens OX=9606 GN=ESYT1 PE=1 SV=1 9.79 3956.2 - 2.30E+06 - - - -2.095 - 2.708 0.357 - 767.5 1 2 0 -0.0027 13 0 0 0 0.00E+00 0.00E+00 - - - 4.2337 0.9996 221125_WJC_METTL3_EV_vs_WT_F01.22054.22054.2 0.000261 20-Aug K.TFSFAIPLIEK.L sp|Q9NR30|DDX21_HUMAN 1 1264.7067 -1 9390 22054 2 1264.70501 633.3606 Nucleolar RNA helicase 2 OS=Homo sapiens OX=9606 GN=DDX21 PE=1 SV=5 5.66 3958.2 - 9.53E+06 - - - -1.356 - 1.757 0.403 - 139.9 1 2 0 -0.0017 11 0 0 0 0.00E+00 0.00E+00 - - - 3.5417 0.994 221125_WJC_METTL3_EV_vs_WT_F01.22058.22058.2 0.00749 14-Jul R.GFGFILFK.D "sp|Q99729|ROAA_HUMAN,tr|D6R9P3|D6R9P3_HUMAN,tr|D6RD18|D6RD18_HUMAN,tr|D6RBZ0|D6RBZ0_HUMAN" 4 927.5218 -1 9394 22058 2 927.520196 464.7682 Heterogeneous nuclear ribonucleoprotein A\B OS=Homo sapiens OX=9606 GN=HNRNPAB PE=1 SV=2 8.75 3958.4 - 4.41E+06 - - - -1.7563 - 1.447 0.17 - 151.6 1 2 0 -0.0016 8 0 0 0 0.00E+00 0.00E+00 - - - 1.4105 1 221125_WJC_METTL3_EV_vs_WT_F01.22059.22059.2 1.09E-07 16/26 M.VLLESEQFLTELTR.L "sp|P37108|SRP14_HUMAN,tr|H0YLA2|H0YLA2_HUMAN" 2 1676.8985 -1 9395 22059 2 1676.896155 839.4565 Signal recognition particle 14 kDa protein OS=Homo sapiens OX=9606 GN=SRP14 PE=1 SV=2 4.25 3958.4 - 4.39E+06 - - - -1.3996 - 3.253 0.561 - 865.2 1 2 0 -0.0023 14 0 0 0 0.00E+00 0.00E+00 - - - 6.1439 1 221125_WJC_METTL3_EV_vs_WT_F01.22060.22060.2 2.03E-07 14/26 M.VLLESEQFLTELTR[166.11].L "sp|P37108|SRP14_HUMAN,tr|H0YLA2|H0YLA2_HUMAN" 2 1686.9068 -1 9396 22060 2 1686.903794 844.4607 Signal recognition particle 14 kDa protein OS=Homo sapiens OX=9606 GN=SRP14 PE=1 SV=2 4.25 3958.5 - 4.28E+06 - - - -1.7654 - 3.093 0.601 - 718.5 1 2 0 -0.003 14 0 0 0 0.00E+00 0.00E+00 - - - 6.3126 0.9941 221125_WJC_METTL3_EV_vs_WT_F01.22061.22061.2 0.0726 14-Aug R.GFGFILFK[136.11].D "sp|Q99729|ROAA_HUMAN,tr|D6R9P3|D6R9P3_HUMAN,tr|D6RD18|D6RD18_HUMAN,tr|D6RBZ0|D6RBZ0_HUMAN" 4 935.536 1.11 9397 22061 2 935.534276 468.7753 Heterogeneous nuclear ribonucleoprotein A\B OS=Homo sapiens OX=9606 GN=HNRNPAB PE=1 SV=2 8.75 3958.6 - 4.14E+06 - - - -1.8695 - 1.5 0.165 - 204.1 1 2 0 -0.0017 8 0 0 0 1.83E+07 1.65E+07 - - - 1.482 1 221125_WJC_METTL3_EV_vs_WT_F01.22065.22065.2 5.71E-09 22-Nov K.LIC[160.03]C[160.03]DILDVLDK.H "sp|P62258|1433E_HUMAN,tr|K7EIT4|K7EIT4_HUMAN" 2 1475.7364 -1 9401 22065 2 1475.734695 738.8755 14-3-3 protein epsilon OS=Homo sapiens OX=9606 GN=YWHAE PE=1 SV=1 3.93 3958.8 - 2.11E+06 - - - -1.1472 - 2.463 0.623 - 375.9 1 2 0 -0.0017 12 0 0 0 0.00E+00 0.00E+00 - - - 6.0136 0.9995 221125_WJC_METTL3_EV_vs_WT_F01.22066.22066.2 8.32E-07 22-Nov K.LIC[160.03]C[160.03]DILDVLDK[136.11].H "sp|P62258|1433E_HUMAN,tr|K7EIT4|K7EIT4_HUMAN" 2 1483.7506 1.01 9402 22066 2 1483.746938 742.8826 14-3-3 protein epsilon OS=Homo sapiens OX=9606 GN=YWHAE PE=1 SV=1 3.93 3958.9 - 1.95E+06 - - - -2.46 - 2.205 0.441 - 335.6 1 2 0 -0.0037 12 0 0 0 4.49E+06 4.43E+06 - - - 4.3776 1 221125_WJC_METTL3_EV_vs_WT_F01.22068.22068.3 3.85E-09 15/52 M.VLLESEQFLTELTR.L "sp|P37108|SRP14_HUMAN,tr|H0YLA2|H0YLA2_HUMAN" 2 1676.8985 -1 9404 22068 3 1676.897478 559.9734 Signal recognition particle 14 kDa protein OS=Homo sapiens OX=9606 GN=SRP14 PE=1 SV=2 4.25 3959.1 - 1.58E+06 - - - -0.6107 - 3.199 0.579 - 285.7 1 2 0 -0.001 14 0 0 0 0.00E+00 0.00E+00 - - - 8.0853 0.9997 221125_WJC_METTL3_EV_vs_WT_F01.22069.22069.3 1.62E-05 Dec-52 M.VLLESEQFLTELTR[166.11].L "sp|P37108|SRP14_HUMAN,tr|H0YLA2|H0YLA2_HUMAN" 2 1686.9068 -1 9405 22069 3 1686.905636 563.3095 Signal recognition particle 14 kDa protein OS=Homo sapiens OX=9606 GN=SRP14 PE=1 SV=2 4.25 3959.1 - 1.58E+06 - - - -0.6734 - 2.386 0.314 - 209.9 1 2 0 -0.0011 14 0 0 0 0.00E+00 0.00E+00 - - - 4.3515 0.9998 221125_WJC_METTL3_EV_vs_WT_F01.22070.22070.2 8.05E-05 18-Nov K.STLLLLLTGK.L "sp|Q8NE71|ABCF1_HUMAN,tr|Q5STZ8|Q5STZ8_HUMAN,tr|H0YGW7|H0YGW7_HUMAN" 3 1057.6747 -1 9406 22070 2 1057.673186 529.8446 ATP-binding cassette sub-family F member 1 OS=Homo sapiens OX=9606 GN=ABCF1 PE=1 SV=2 8.47 3959.3 - 1.00E+06 - - - -1.4286 - 2.149 0.517 - 416.2 1 2 0 -0.0015 10 0 0 0 0.00E+00 0.00E+00 - - - 4.9944 0.9997 221125_WJC_METTL3_EV_vs_WT_F01.22073.22073.2 0.00119 20-Oct K.EVLDSFLDLAR[166.11].N sp|Q15758|AAAT_HUMAN 1 1286.6746 -1 9408 22073 2 1286.67242 644.3446 Neutral amino acid transporter B(0) OS=Homo sapiens OX=9606 GN=SLC1A5 PE=1 SV=2 4.03 3959.6 - 495942 - - - -1.6842 - 2.147 0.421 - 368.9 1 2 0 -0.0022 11 0 0 0 0.00E+00 0.00E+00 - - - 4.2168 0.9998 221125_WJC_METTL3_EV_vs_WT_F01.22074.22074.2 0.000224 22-Nov R.FNVLQYVVPEVK.D sp|Q14152|EIF3A_HUMAN 1 1433.7919 -1 9409 22074 2 1433.790362 717.9032 Eukaryotic translation initiation factor 3 subunit A OS=Homo sapiens OX=9606 GN=EIF3A PE=1 SV=1 6 3959.8 - 570560 - - - -1.0392 - 2.206 0.478 - 417.8 1 2 0 -0.0015 12 0 0 0 0.00E+00 0.00E+00 - - - 4.6528 0.9999 221125_WJC_METTL3_EV_vs_WT_F01.22078.22078.2 1.97E-05 20-Nov K.LVLADLLEPVK.T sp|Q9BVJ6|UT14A_HUMAN 1 1208.738 2.01 9413 22078 2 1208.739015 605.3763 U3 small nucleolar RNA-associated protein 14 homolog A OS=Homo sapiens OX=9606 GN=UTP14A PE=1 SV=1 4.37 3960 - 3.49E+06 - - - 0.8182 - 2.212 0.569 - 314 1 2 0 0.001 11 0 0 0 2.35E+07 1.17E+07 - - - 5.391 0.9998 221125_WJC_METTL3_EV_vs_WT_F01.22082.22082.2 7.87E-05 24-Dec K.IPLKPPPLELLNV.- sp|O15504|NUP42_HUMAN 1 1441.8908 2.5 9417 22082 2 1441.888743 721.9527 Nucleoporin NUP42 OS=Homo sapiens OX=9606 GN=NUP42 PE=1 SV=1 6 3960.2 - 1.54E+06 - - - -1.453 - 2.161 0.466 - 444.8 1 2 0 -0.0021 13 0 0 0 8.42E+06 3.36E+06 - - - 4.4599 1 221125_WJC_METTL3_EV_vs_WT_F01.22087.22087.2 7.56E-10 17/26 K.MQLMELAILNGTYR.D "sp|Q96PU8|QKI_HUMAN,tr|F5GYM3|F5GYM3_HUMAN,tr|F5GXS8|F5GXS8_HUMAN,tr|H0YG47|H0YG47_HUMAN,tr|H0YGD6|H0YGD6_HUMAN" 5 1651.8426 -1 9422 22087 2 1651.839313 826.9286 Protein quaking OS=Homo sapiens OX=9606 GN=QKI PE=1 SV=1 5.75 3960.8 - 1.09E+06 - - - -1.9802 - 3.275 0.658 - 1064.8 1 2 0 -0.0033 14 0 0 0 0.00E+00 0.00E+00 - - - 6.877 0.9995 221125_WJC_METTL3_EV_vs_WT_F01.22092.22092.2 0.0711 24-Oct K.IPLK[136.11]PPPLELLNV.- sp|O15504|NUP42_HUMAN 1 1449.905 2.5 9427 22092 2 1449.904327 725.9598 Nucleoporin NUP42 OS=Homo sapiens OX=9606 GN=NUP42 PE=1 SV=1 6 3961.4 - 736850 - - - -0.4904 - 1.746 0.343 - 260.8 1 2 0 -0.0007 13 0 0 0 8.42E+06 3.36E+06 - - - 3.0046 0.9996 221125_WJC_METTL3_EV_vs_WT_F01.22100.22100.2 0.0125 20-Nov R.SFWELIGEAAK.S sp|Q9HCY8|S10AE_HUMAN 1 1249.6343 -1 9434 22100 2 1249.632072 625.8244 Protein S100-A14 OS=Homo sapiens OX=9606 GN=S100A14 PE=1 SV=1 4.53 3962 - 2.26E+06 - - - -1.7741 - 1.888 0.425 - 348 1 2 0 -0.0022 11 0 0 0 0.00E+00 0.00E+00 - - - 3.8986 0.9994 221125_WJC_METTL3_EV_vs_WT_F01.22101.22101.2 0.0505 18-Nov K.FLLFSSLVTK.E "sp|Q15155|NOMO1_HUMAN,sp|Q5JPE7|NOMO2_HUMAN,sp|P69849|NOMO3_HUMAN,tr|A0A7I2V686|A0A7I2V686_HUMAN,tr|A0A7I2V3P4|A0A7I2V3P4_HUMAN,tr|A0A7I2V6B0|A0A7I2V6B0_HUMAN,tr|A0A7I2V4D7|A0A7I2V4D7_HUMAN,tr|A0A7I2V4T6|A0A7I2V4T6_HUMAN,tr|A0A0G2JP90|A0A0G2JP90_HUMAN,tr|A0A087X117|A0A087X117_HUMAN,tr|A0A0G2JN29|A0A0G2JN29_HUMAN,tr|A0A7I2V2Z5|A0A7I2V2Z5_HUMAN,tr|A0A087WW46|A0A087WW46_HUMAN,tr|J3KN36|J3KN36_HUMAN" 14 1153.6747 -1 9435 22101 2 1153.671974 577.8446 Nodal modulator 1 OS=Homo sapiens OX=9606 GN=NOMO1 PE=1 SV=5 8.75 3962.1 - 1.93E+06 - - - -2.3603 - 1.952 0.405 - 354.8 1 2 0 -0.0027 10 0 0 0 0.00E+00 0.00E+00 - - - 3.8985 0.9994 221125_WJC_METTL3_EV_vs_WT_F01.22106.22106.2 0.00618 16-Sep K.SGNYFFLDD.- sp|P61221|ABCE1_HUMAN 1 1076.4451 - 9440 22106 2 1076.443003 539.2298 ATP-binding cassette sub-family E member 1 OS=Homo sapiens OX=9606 GN=ABCE1 PE=1 SV=1 3.89 3962.6 - 1.08E+06 - - - -1.9397 - 1.502 0.451 - 219.1 1 2 0 -0.0021 9 0 0 0 - - - - - 3.5483 0.9998 221125_WJC_METTL3_EV_vs_WT_F01.22107.22107.2 3.90E-05 15/22 K.QFEELTLGEFLK.L "sp|O15392|BIRC5_HUMAN,tr|A0A0B4J1S3|A0A0B4J1S3_HUMAN,tr|K7EMW2|K7EMW2_HUMAN,tr|H3BLT4|H3BLT4_HUMAN" 4 1452.75 1.89 9441 22107 2 1452.747068 727.3823 Baculoviral IAP repeat-containing protein 5 OS=Homo sapiens OX=9606 GN=BIRC5 PE=1 SV=3 4.25 3962.7 - 1.08E+06 - - - -2.0506 - 2.768 0.505 - 1003.1 1 2 0 -0.003 12 0 0 0 7.11E+06 3.76E+06 - - - 5.4489 0.995 221125_WJC_METTL3_EV_vs_WT_F01.22109.22109.2 0.246 14-Aug K.GSLLDFLK[136.11].E "sp|P07947|YES_HUMAN,sp|P09769|FGR_HUMAN,sp|P07948|LYN_HUMAN,sp|P08631|HCK_HUMAN,sp|P06241|FYN_HUMAN,sp|P12931|SRC_HUMAN,tr|H0Y3C5|H0Y3C5_HUMAN,tr|J3KPD6|J3KPD6_HUMAN,tr|J3QRU1|J3QRU1_HUMAN" 9 899.5208 -1 9443 22109 2 899.519015 450.7677 Tyrosine-protein kinase Yes OS=Homo sapiens OX=9606 GN=YES1 PE=1 SV=3 5.84 3963 - 1.06E+06 - - - -1.9499 - 1.652 0.147 - 211.2 1 2 0 -0.0018 8 0 0 0 0.00E+00 0.00E+00 - - - 1.6402 0.9998 221125_WJC_METTL3_EV_vs_WT_F01.22110.22110.2 1.24E-05 20-Sep R.YFGELLADLSR.K sp|Q8WVV4|POF1B_HUMAN 1 1282.6558 49.97 9444 22110 2 1282.653787 642.3352 Protein POF1B OS=Homo sapiens OX=9606 GN=POF1B PE=1 SV=3 4.37 3963.1 - 886993 - - - -1.532 - 2.033 0.585 - 230.7 1 2 0 -0.002 11 0 0 0 5.00E+06 1.00E+05 - - - 5.2806 0.8692 221125_WJC_METTL3_EV_vs_WT_F01.22111.22111.2 0.0694 20-Sep K.FLTLPPVLHLQ.L "sp|Q93009|UBP7_HUMAN,tr|A0A669KBL1|A0A669KBL1_HUMAN,tr|F5H2X1|F5H2X1_HUMAN,tr|H3BND8|H3BND8_HUMAN" 4 1276.7543 - 9445 22111 2 1276.751516 639.3844 Ubiquitin carboxyl-terminal hydrolase 7 OS=Homo sapiens OX=9606 GN=USP7 PE=1 SV=2 6.74 3963.2 - 816470 - - - -2.215 - 1.668 0.264 - 239.9 1 1 0 -0.0028 11 0 0 0 - - - - - 2.3741 0.9733 221125_WJC_METTL3_EV_vs_WT_F01.22115.22115.2 0.426 14-Jul K.GSLLDFLK.E "sp|P07947|YES_HUMAN,sp|P09769|FGR_HUMAN,sp|P07948|LYN_HUMAN,sp|P08631|HCK_HUMAN,sp|P06241|FYN_HUMAN,sp|P12931|SRC_HUMAN,tr|H0Y3C5|H0Y3C5_HUMAN,tr|J3KPD6|J3KPD6_HUMAN,tr|J3QRU1|J3QRU1_HUMAN" 9 891.5066 -1 9448 22115 2 891.504875 446.7606 Tyrosine-protein kinase Yes OS=Homo sapiens OX=9606 GN=YES1 PE=1 SV=3 5.84 3963.7 - 913082 - - - -1.9002 - 1.342 0.085 - 147.2 2 2 0 -0.0017 8 0 0 0 0.00E+00 0.00E+00 - - - 0.421 0.9998 221125_WJC_METTL3_EV_vs_WT_F01.22117.22117.2 5.91E-07 14/22 R.NLDLDSIIAEVK.A "sp|P48668|K2C6C_HUMAN,sp|P04259|K2C6B_HUMAN,sp|P13647|K2C5_HUMAN,sp|P35908|K22E_HUMAN,sp|O95678|K2C75_HUMAN,sp|Q5XKE5|K2C79_HUMAN,sp|P02538|K2C6A_HUMAN,tr|H0YI76|H0YI76_HUMAN,tr|H0YIN9|H0YIN9_HUMAN" 9 1328.7187 -1 9450 22117 2 1328.716223 665.3666 "Keratin, type II cytoskeletal 6C OS=Homo sapiens OX=9606 GN=KRT6C PE=1 SV=3" 4.03 3963.9 - 7.64E+06 - - - -1.8996 - 2.714 0.497 - 517.2 1 2 0 -0.0025 12 0 0 0 0.00E+00 0.00E+00 - - - 5.3381 1 221125_WJC_METTL3_EV_vs_WT_F01.22124.22124.2 2.26E-07 18/28 T.VSLGGFEITPPVVLR.L "sp|P06748|NPM_HUMAN,tr|E5RI98|E5RI98_HUMAN,tr|A0A7I2YQC0|A0A7I2YQC0_HUMAN,tr|A0A7I2V433|A0A7I2V433_HUMAN,tr|A0A7I2V2X9|A0A7I2V2X9_HUMAN,tr|A0A7I2V5J8|A0A7I2V5J8_HUMAN,tr|A0A7I2V5S2|A0A7I2V5S2_HUMAN,tr|A0A7I2V3U2|A0A7I2V3U2_HUMAN" 8 1582.9083 1.25 9457 22124 2 1582.904228 792.4614 Nucleophosmin OS=Homo sapiens OX=9606 GN=NPM1 PE=1 SV=2 5.97 3964.5 - 1.28E+06 - - - -2.5592 - 3.006 0.559 - 1046 1 1 0 -0.0041 15 0 0 0 5.28E+06 4.23E+06 - - - 5.8744 1 221125_WJC_METTL3_EV_vs_WT_F01.22125.22125.2 4.55E-08 14/34 K.LLGTIYTAAEEIEAVGGK[136.11].A sp|Q6YN16|HSDL2_HUMAN 1 1841.9866 -1 9458 22125 2 1841.983395 922.0006 Hydroxysteroid dehydrogenase-like protein 2 OS=Homo sapiens OX=9606 GN=HSDL2 PE=1 SV=1 4.25 3964.6 - 1.15E+06 - - - -1.7373 - 2.769 0.604 - 568.4 1 2 0 -0.0032 18 0 0 0 0.00E+00 0.00E+00 - - - 6.0051 0.9984 221125_WJC_METTL3_EV_vs_WT_F01.22128.22128.2 0.659 16-Jul K.IAILGFAFK.K sp|O60701|UGDH_HUMAN 1 978.5902 -1 9461 22128 2 978.58878 490.3024 UDP-glucose 6-dehydrogenase OS=Homo sapiens OX=9606 GN=UGDH PE=1 SV=1 8.75 3965 - 896326 - - - -1.4909 - 1.649 0.252 - 77.5 1 2 0 -0.0015 9 0 0 0 0.00E+00 0.00E+00 - - - 2.3488 0.9987 221125_WJC_METTL3_EV_vs_WT_F01.22134.22134.2 0.00996 14/22 R.SLDLDSIIAEVK.A sp|P04264|K2C1_HUMAN 1 1301.7078 999 9467 22134 2 1301.701749 651.8612 "Keratin, type II cytoskeletal 1 OS=Homo sapiens OX=9606 GN=KRT1 PE=1 SV=6" 4.03 3965.8 - 510690 - - - -4.6854 - 2.787 0.528 - 454.4 1 2 0 -0.0061 12 0 0 0 3.37E+07 0.00E+00 - - - 5.6358 0.9691 221125_WJC_METTL3_EV_vs_WT_F01.22138.22138.2 0.00145 14-Aug K.KEDLVFIF.W "sp|P23528|COF1_HUMAN,sp|Q9Y281|COF2_HUMAN,tr|E9PP50|E9PP50_HUMAN,tr|G3V1A4|G3V1A4_HUMAN,tr|E9PQB7|E9PQB7_HUMAN,tr|E9PK25|E9PK25_HUMAN" 6 1009.5484 -1 9470 22138 2 1009.546438 505.7815 Cofilin-1 OS=Homo sapiens OX=9606 GN=CFL1 PE=1 SV=3 4.37 3966.3 - 6.81E+06 - - - -1.9771 - 1.49 0.481 - 209.3 1 1 0 -0.002 8 0 0 0 0.00E+00 0.00E+00 - - - 3.7957 0.9997 221125_WJC_METTL3_EV_vs_WT_F01.22142.22142.2 2.32E-05 18-Dec K.NIFAILQSVK.A "sp|Q6P1J9|CDC73_HUMAN,tr|A0A2R8YHB3|A0A2R8YHB3_HUMAN,tr|A0A3B3IRP5|A0A3B3IRP5_HUMAN" 3 1131.6652 -1 9474 22142 2 1131.664066 566.8399 Parafibromin OS=Homo sapiens OX=9606 GN=CDC73 PE=1 SV=1 8.75 3966.6 - 2.11E+06 - - - -0.9976 - 2.197 0.347 - 381.1 1 2 0 -0.0011 10 0 0 0 0.00E+00 0.00E+00 - - - 3.8006 0.989 221125_WJC_METTL3_EV_vs_WT_F01.22143.22143.2 3.35E-07 28-Nov T.VSLGGFEITPPVVLR[166.11].L "sp|P06748|NPM_HUMAN,tr|E5RI98|E5RI98_HUMAN,tr|A0A7I2YQC0|A0A7I2YQC0_HUMAN,tr|A0A7I2V433|A0A7I2V433_HUMAN,tr|A0A7I2V2X9|A0A7I2V2X9_HUMAN,tr|A0A7I2V5J8|A0A7I2V5J8_HUMAN,tr|A0A7I2V5S2|A0A7I2V5S2_HUMAN,tr|A0A7I2V3U2|A0A7I2V3U2_HUMAN" 8 1592.9165 -1 9475 22143 2 1592.91363 797.4656 Nucleophosmin OS=Homo sapiens OX=9606 GN=NPM1 PE=1 SV=2 5.97 3966.6 - 1.77E+06 - - - -1.8325 - 2.6 0.53 - 342.7 1 1 0 -0.0029 15 0 0 0 0.00E+00 0.00E+00 - - - 5.3038 0.7898 221125_WJC_METTL3_EV_vs_WT_F01.22144.22144.2 0.105 12-May K.WELLQQM.N sp|P35908|K22E_HUMAN 1 946.4582 - 9476 22144 2 946.456676 474.2364 "Keratin, type II cytoskeletal 2 epidermal OS=Homo sapiens OX=9606 GN=KRT2 PE=1 SV=2" 4 3966.7 - 1.76E+06 - - - -1.6514 - 1.083 0.311 - 121.7 1 1 0 -0.0016 7 0 0 0 - - - - - 1.5902 0.9999 221125_WJC_METTL3_EV_vs_WT_F01.22147.22147.2 0.000185 14/24 R.DPQLVPILIEAAR.N "sp|Q15738|NSDHL_HUMAN,tr|C9JDR0|C9JDR0_HUMAN" 2 1433.8242 -1 9479 22147 2 1433.823542 717.9194 "Sterol-4-alpha-carboxylate 3-dehydrogenase, decarboxylating OS=Homo sapiens OX=9606 GN=NSDHL PE=1 SV=2" 4.37 3967 - 1.58E+06 - - - -0.4694 - 2.503 0.467 - 403.3 1 2 0 -0.0007 13 0 0 0 0.00E+00 0.00E+00 - - - 4.8448 0.9999 221125_WJC_METTL3_EV_vs_WT_F01.22151.22151.2 3.12E-08 22-Oct R.LGDPLEAFPVFK[136.11].K "sp|Q86UY6|NAA40_HUMAN,tr|F5H2C9|F5H2C9_HUMAN" 2 1339.7267 1.17 9483 22151 2 1339.725358 670.8706 N-alpha-acetyltransferase 40 OS=Homo sapiens OX=9606 GN=NAA40 PE=1 SV=1 4.37 3967.4 - 1.14E+06 - - - -1.0308 - 2.18 0.592 - 342.7 1 2 0 -0.0014 12 0 0 0 4.74E+06 4.04E+06 - - - 5.4636 0.9983 221125_WJC_METTL3_EV_vs_WT_F01.22153.22153.2 0.0242 16-Aug K.EVWDYVFFK.E "sp|Q9P2J5|SYLC_HUMAN,tr|A0A6I8PIV1|A0A6I8PIV1_HUMAN,tr|A0A6I8PRS0|A0A6I8PRS0_HUMAN,tr|A0A6I8PLB8|A0A6I8PLB8_HUMAN,tr|A0A6I8PIP7|A0A6I8PIP7_HUMAN,tr|A0A6I8PIT3|A0A6I8PIT3_HUMAN,tr|A0A6I8PRP1|A0A6I8PRP1_HUMAN,tr|A0A6I8PTV8|A0A6I8PTV8_HUMAN,tr|A0A6I8PLB3|A0A6I8PLB3_HUMAN,tr|A0A6I8PS05|A0A6I8PS05_HUMAN,tr|B4DER1|B4DER1_HUMAN,tr|A0A6I8PL42|A0A6I8PL42_HUMAN" 12 1231.5914 -1 9485 22153 2 1231.590664 616.803 "Leucine--tRNA ligase, cytoplasmic OS=Homo sapiens OX=9606 GN=LARS1 PE=1 SV=2" 4.37 3967.6 - 975597 - - - -0.5659 - 1.419 0.258 - 186.2 1 2 0 -0.0007 9 0 0 0 0.00E+00 0.00E+00 - - - 1.9588 0.9999 221125_WJC_METTL3_EV_vs_WT_F01.22154.22154.2 4.32E-07 22-Nov K.LIQLMEEIMAEK.E "sp|Q92841|DDX17_HUMAN,tr|A0A5H1ZRQ2|A0A5H1ZRQ2_HUMAN,tr|A0A1X7SBZ2|A0A1X7SBZ2_HUMAN" 3 1446.7462 -1 9486 22154 2 1446.747865 724.3804 Probable ATP-dependent RNA helicase DDX17 OS=Homo sapiens OX=9606 GN=DDX17 PE=1 SV=2 4.25 3967.7 - 903913 - - - 1.1343 - 2.294 0.574 - 379.5 1 2 0 0.0016 12 0 0 0 0.00E+00 0.00E+00 - - - 5.4647 0.9999 221125_WJC_METTL3_EV_vs_WT_F01.22155.22155.3 1.64E-05 Dec-48 R.DPQLVPILIEAAR.N "sp|Q15738|NSDHL_HUMAN,tr|C9JDR0|C9JDR0_HUMAN" 2 1433.8242 -1 9487 22155 3 1433.823174 478.9487 "Sterol-4-alpha-carboxylate 3-dehydrogenase, decarboxylating OS=Homo sapiens OX=9606 GN=NSDHL PE=1 SV=2" 4.37 3967.8 - 858519 - - - -0.726 - 2.65 0.407 - 323.4 1 2 0 -0.001 13 0 0 0 0.00E+00 0.00E+00 - - - 5.7197 0.9998 221125_WJC_METTL3_EV_vs_WT_F01.22159.22159.2 0.326 18-Nov R.ILGLLDAYLK[136.11].T sp|P26641|EF1G_HUMAN 1 1125.6889 0.92 9490 22159 2 1125.689325 563.8517 Elongation factor 1-gamma OS=Homo sapiens OX=9606 GN=EEF1G PE=1 SV=3 5.83 3968.2 - 5.01E+06 - - - 0.3802 - 2.348 0.333 - 296.3 1 2 0 0.0004 10 0 0 0 7.49E+06 8.14E+06 - - - 3.883 0.9996 221125_WJC_METTL3_EV_vs_WT_F01.22160.22160.2 0.00082 18-Nov R.ILGLLDAYLK.T sp|P26641|EF1G_HUMAN 1 1117.6747 0.92 9491 22160 2 1117.675312 559.8446 Elongation factor 1-gamma OS=Homo sapiens OX=9606 GN=EEF1G PE=1 SV=3 5.83 3968.2 - 4.69E+06 - - - 0.5502 - 2.257 0.271 - 268.5 1 2 0 0.0006 10 0 0 0 7.49E+06 8.14E+06 - - - 3.3146 0.9996 221125_WJC_METTL3_EV_vs_WT_F01.22161.22161.2 0.342 18-Oct K.NIFAILQSVK[136.11].A "sp|Q6P1J9|CDC73_HUMAN,tr|A0A2R8YHB3|A0A2R8YHB3_HUMAN,tr|A0A3B3IRP5|A0A3B3IRP5_HUMAN" 3 1139.6794 -1 9492 22161 2 1139.679699 570.847 Parafibromin OS=Homo sapiens OX=9606 GN=CDC73 PE=1 SV=1 8.75 3968.3 - 3.64E+06 - - - 0.2667 - 1.96 0.322 - 223.3 1 2 0 0.0003 10 0 0 0 0.00E+00 0.00E+00 - - - 3.2976 0.9992 221125_WJC_METTL3_EV_vs_WT_F01.22163.22163.2 0.0679 14-Jul R.VDEIIWVK[136.11].T sp|Q86U44|MTA70_HUMAN 1 1008.5735 0.07 9494 22163 2 1008.573562 505.294 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 4.37 3968.4 - 1.49E+06 - - - 0.0288 - 1.806 0.243 - 159.8 1 2 0 0 8 0 0 0 5.14E+05 7.32E+06 - - - 2.6186 0.9999 221125_WJC_METTL3_EV_vs_WT_F01.22165.22165.2 1.24E-05 18-Oct R.DFVVGALILR[166.11].S sp|Q9NUD5|ZCHC3_HUMAN 1 1111.6629 -1 9496 22165 2 1111.663523 556.8387 Zinc finger CCHC domain-containing protein 3 OS=Homo sapiens OX=9606 GN=ZCCHC3 PE=1 SV=2 5.84 3968.7 - 1.08E+06 - - - 0.5604 - 2.114 0.492 - 434.5 1 2 0 0.0006 10 0 0 0 0.00E+00 0.00E+00 - - - 4.7642 0.9999 221125_WJC_METTL3_EV_vs_WT_F01.22167.22167.2 1.19E-06 18-Oct R.DFVVGALILR.S sp|Q9NUD5|ZCHC3_HUMAN 1 1101.6546 -1 9498 22167 2 1101.655073 551.8346 Zinc finger CCHC domain-containing protein 3 OS=Homo sapiens OX=9606 GN=ZCCHC3 PE=1 SV=2 5.84 3968.9 - 989035 - - - 0.4021 - 2.063 0.555 - 427.1 1 2 0 0.0004 10 0 0 0 0.00E+00 0.00E+00 - - - 5.1614 0.9999 221125_WJC_METTL3_EV_vs_WT_F01.22168.22168.2 4.83E-05 14/22 R.LGPLLDILADSR[166.11].H "sp|Q13724|MOGS_HUMAN,tr|A0A3B3IRK6|A0A3B3IRK6_HUMAN,tr|A0A3B3IRW2|A0A3B3IRW2_HUMAN" 3 1291.7375 0.85 9499 22168 2 1291.738118 646.876 Mannosyl-oligosaccharide glucosidase OS=Homo sapiens OX=9606 GN=MOGS PE=1 SV=5 4.21 3969 - 783152 - - - 0.4614 - 2.951 0.506 - 862.5 1 2 0 0.0006 12 0 0 0 3.79E+06 4.45E+06 - - - 5.6254 0.9997 221125_WJC_METTL3_EV_vs_WT_F01.22171.22171.3 7.55E-05 Nov-44 K.LR[166.11]EC[160.03]LPLIIFLR[166.11].N sp|P62701|RS4X_HUMAN 1 1561.9281 0.71 9502 22171 3 1561.928967 521.65 "40S ribosomal protein S4, X isoform OS=Homo sapiens OX=9606 GN=RPS4X PE=1 SV=2" 8.25 3969.4 - 676707 - - - 0.5359 - 2.354 0.433 - 192.6 1 2 1 0.0008 12 0 0 0 1.48E+06 2.08E+06 - - - 5.7403 0.9999 221125_WJC_METTL3_EV_vs_WT_F01.22173.22173.3 3.83E-06 Dec-44 K.LREC[160.03]LPLIIFLR.N sp|P62701|RS4X_HUMAN 1 1541.9116 0.71 9504 22173 3 1541.91198 514.9778 "40S ribosomal protein S4, X isoform OS=Homo sapiens OX=9606 GN=RPS4X PE=1 SV=2" 8.25 3969.7 - 599656 - - - 0.2529 - 2.646 0.522 - 279.5 1 2 1 0.0004 12 0 0 0 1.48E+06 2.08E+06 - - - 7.0568 0.9998 221125_WJC_METTL3_EV_vs_WT_F01.22176.22176.2 0.000451 22-Oct R.VLGLLGALDPYK.H sp|P42345|MTOR_HUMAN 1 1257.7333 -1 9507 22176 2 1257.73337 629.8739 Serine\threonine-protein kinase mTOR OS=Homo sapiens OX=9606 GN=MTOR PE=1 SV=1 5.81 3970 - 561620 - - - 0.0755 - 2.009 0.412 - 368.5 1 2 0 0.0001 12 0 0 0 0.00E+00 0.00E+00 - - - 3.9196 0.8905 221125_WJC_METTL3_EV_vs_WT_F01.22179.22179.2 0.024 12-Jun K.TSFFQAL.G "sp|Q8NHW5|RLA0L_HUMAN,sp|P05388|RLA0_HUMAN,tr|G3V210|G3V210_HUMAN,tr|F8VU65|F8VU65_HUMAN,tr|F8VWS0|F8VWS0_HUMAN,tr|F8VW21|F8VW21_HUMAN,tr|F8VRK7|F8VRK7_HUMAN,tr|F8VQY6|F8VQY6_HUMAN,tr|F8VPE8|F8VPE8_HUMAN" 9 812.4069 - 9509 22179 2 812.407196 407.2107 60S acidic ribosomal protein P0-like OS=Homo sapiens OX=9606 GN=RPLP0P6 PE=5 SV=1 5.19 3970.4 - 1.67E+06 - - - 0.4197 - 1.231 0.288 - 142 1 1 0 0.0003 7 0 0 0 - - - - - 1.8266 0.8569 221125_WJC_METTL3_EV_vs_WT_F01.22181.22181.2 0.139 20-Jun R.FSDHVALLSVF.Q sp|Q08211|DHX9_HUMAN 1 1233.6394 - 9511 22181 2 1233.63981 617.827 ATP-dependent RNA helicase A OS=Homo sapiens OX=9606 GN=DHX9 PE=1 SV=4 5.08 3970.5 - 1.14E+06 - - - 0.3534 - 1.276 0.272 - 80.2 2 1 0 0.0004 11 0 0 0 - - - - - 1.5747 0.9998 221125_WJC_METTL3_EV_vs_WT_F01.22183.22183.2 1.54E-05 20-Sep R.EVTPFFIIYC[160.03]R.A sp|Q02413|DSG1_HUMAN 1 1443.7221 -1 9513 22183 2 1443.723776 722.8683 Desmoglein-1 OS=Homo sapiens OX=9606 GN=DSG1 PE=1 SV=2 6.09 3970.7 - 988483 - - - 1.19 - 1.87 0.482 - 367.4 1 2 0 0.0017 11 0 0 0 0.00E+00 0.00E+00 - - - 4.2938 0.9997 221125_WJC_METTL3_EV_vs_WT_F01.22190.22190.2 0.000248 22-Dec K.IIDEDGLLNLIR.T "sp|P35251|RFC1_HUMAN,tr|H0Y8U4|H0Y8U4_HUMAN" 2 1382.7769 -1 9520 22190 2 1382.777778 692.3957 Replication factor C subunit 1 OS=Homo sapiens OX=9606 GN=RFC1 PE=1 SV=4 4.03 3971.6 - 415909 - - - 0.6133 - 2.23 0.325 - 416.3 1 2 0 0.0008 12 0 0 0 0.00E+00 0.00E+00 - - - 3.5514 0.9997 221125_WJC_METTL3_EV_vs_WT_F01.22191.22191.2 0.0009 22-Dec K.IIDEDGLLNLIR[166.11].T "sp|P35251|RFC1_HUMAN,tr|H0Y8U4|H0Y8U4_HUMAN" 2 1392.7852 -1 9521 22191 2 1392.787577 697.3999 Replication factor C subunit 1 OS=Homo sapiens OX=9606 GN=RFC1 PE=1 SV=4 4.03 3971.7 - 409294 - - - 1.7067 - 2.159 0.465 - 382.2 1 2 0 0.0024 12 0 0 0 0.00E+00 0.00E+00 - - - 4.4998 0.9965 221125_WJC_METTL3_EV_vs_WT_F01.22193.22193.2 0.0314 24-Jun R.VSELQVLLGYAGR.N "sp|O75925|PIAS1_HUMAN,tr|H3BSI8|H3BSI8_HUMAN" 2 1403.7773 -1 9523 22193 2 1403.77801 702.8959 E3 SUMO-protein ligase PIAS1 OS=Homo sapiens OX=9606 GN=PIAS1 PE=1 SV=2 5.97 3972 - 385068 - - - 0.5307 - 1.542 0.211 - 73.7 4 2 0 0.0007 13 0 0 0 0.00E+00 0.00E+00 - - - 1.4418 1 221125_WJC_METTL3_EV_vs_WT_F01.22197.22197.2 1.55E-07 24-Dec R.SDFFLEGPFMPPR[166.11].M "sp|P78344|IF4G2_HUMAN,tr|H0Y3P2|H0Y3P2_HUMAN,tr|H0YCH5|H0YCH5_HUMAN,tr|D3DQV9|D3DQV9_HUMAN" 4 1548.7311 2.3 9527 22197 2 1548.731555 775.3728 Eukaryotic translation initiation factor 4 gamma 2 OS=Homo sapiens OX=9606 GN=EIF4G2 PE=1 SV=1 4.37 3972.5 - 293342 - - - 0.3222 - 2.757 0.613 - 386.2 1 2 0 0.0005 13 0 0 0 7.49E+06 3.26E+06 - - - 6.1713 0.9621 221125_WJC_METTL3_EV_vs_WT_F01.22199.22199.2 0.00928 18-Oct K.LASDLLEWIR.R "sp|O43707|ACTN4_HUMAN,sp|P12814|ACTN1_HUMAN,tr|A0A804HK61|A0A804HK61_HUMAN,tr|G3V2W4|G3V2W4_HUMAN,tr|A0A804HJU8|A0A804HJU8_HUMAN,tr|H9KV75|H9KV75_HUMAN,tr|A0A804HLF4|A0A804HLF4_HUMAN,tr|A0A7I2V4Y4|A0A7I2V4Y4_HUMAN,tr|A0A804HII9|A0A804HII9_HUMAN,tr|A0A804HL31|A0A804HL31_HUMAN,tr|F5GXS2|F5GXS2_HUMAN,tr|A0A804HKE2|A0A804HKE2_HUMAN,tr|A0A804HLD0|A0A804HLD0_HUMAN,tr|H7C144|H7C144_HUMAN" 14 1214.6659 -1 9528 22199 2 1214.677983 608.3402 Alpha-actinin-4 OS=Homo sapiens OX=9606 GN=ACTN4 PE=1 SV=2 4.37 3972.9 - 271265 - - - 9.9287 - 2.318 0.287 - 215.6 1 2 0 0.0121 10 0 0 0 0.00E+00 0.00E+00 - - - 3.5037 1 221125_WJC_METTL3_EV_vs_WT_F01.22202.22202.2 5.20E-08 13/24 R.SDFFLEGPFMPPR.M "sp|P78344|IF4G2_HUMAN,tr|H0Y3P2|H0Y3P2_HUMAN,tr|H0YCH5|H0YCH5_HUMAN,tr|D3DQV9|D3DQV9_HUMAN" 4 1538.7228 2.21 9531 22202 2 1538.722623 770.3687 Eukaryotic translation initiation factor 4 gamma 2 OS=Homo sapiens OX=9606 GN=EIF4G2 PE=1 SV=1 4.37 3973.2 - 1.51E+06 - - - -0.1059 - 2.586 0.601 - 578.6 1 2 0 -0.0002 13 0 0 0 7.49E+06 3.39E+06 - - - 5.9184 1 221125_WJC_METTL3_EV_vs_WT_F01.22205.22205.2 4.35E-07 13/24 R.GNSIIMLEALERV.- "sp|P62308|RUXG_HUMAN,sp|A8MWD9|RUXGL_HUMAN,tr|Q49AN9|Q49AN9_HUMAN,tr|F5H013|F5H013_HUMAN" 4 1443.7756 -1 9534 22205 2 1443.777523 722.8951 Small nuclear ribonucleoprotein G OS=Homo sapiens OX=9606 GN=SNRPG PE=1 SV=1 4.53 3973.5 - 607544 - - - 1.3666 - 2.754 0.599 - 755.8 1 2 0 0.002 13 0 0 0 0.00E+00 0.00E+00 - - - 6.0646 0.9997 221125_WJC_METTL3_EV_vs_WT_F01.22207.22207.2 0.0361 13/22 K.AIIIFVPVPQLK[136.11].S "sp|P62081|RS7_HUMAN,tr|B5MCP9|B5MCP9_HUMAN" 2 1344.8624 0.83 9536 22207 2 1344.863232 673.4385 40S ribosomal protein S7 OS=Homo sapiens OX=9606 GN=RPS7 PE=1 SV=1 8.8 3973.7 - 509916 - - - 0.5852 - 2.331 0.321 - 536 1 2 0 0.0008 12 0 0 0 3.90E+07 4.68E+07 - - - 3.6384 0.7905 221125_WJC_METTL3_EV_vs_WT_F01.22209.22209.2 0.166 16-Jun R.NLDLDSIIA.E "sp|Q86Y46|K2C73_HUMAN,sp|P48668|K2C6C_HUMAN,sp|P19013|K2C4_HUMAN,sp|P04259|K2C6B_HUMAN,sp|P13647|K2C5_HUMAN,sp|P35908|K22E_HUMAN,sp|O95678|K2C75_HUMAN,sp|Q5XKE5|K2C79_HUMAN,sp|P02538|K2C6A_HUMAN,tr|H0YI76|H0YI76_HUMAN,tr|H0YIC5|H0YIC5_HUMAN,tr|H0YIN9|H0YIN9_HUMAN" 12 972.5128 - 9538 22209 2 972.513308 487.2637 "Keratin, type II cytoskeletal 73 OS=Homo sapiens OX=9606 GN=KRT73 PE=1 SV=1" 3.56 3974 - 479464 - - - 0.546 - 1.283 0.204 - 56.8 1 1 0 0.0005 9 0 0 0 - - - - - 1.2685 0.9265 221125_WJC_METTL3_EV_vs_WT_F01.22210.22210.2 0.00285 14-Jul R.EC[160.03]LNLWGY.E sp|Q86U44|MTA70_HUMAN 1 1053.459 - 9539 22210 2 1053.457827 527.7368 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 4 3974.1 - 463004 - - - -1.0821 - 1.453 0.291 - 207.3 1 1 0 -0.0011 8 0 0 0 - - - - - 2.3168 0.9934 221125_WJC_METTL3_EV_vs_WT_F01.22216.22216.2 0.672 24-Aug R.GNSIIMLEALER[166.11]V.- "sp|P62308|RUXG_HUMAN,sp|A8MWD9|RUXGL_HUMAN,tr|Q49AN9|Q49AN9_HUMAN,tr|F5H013|F5H013_HUMAN" 4 1453.7838 -1 9545 22216 2 1453.782445 727.8992 Small nuclear ribonucleoprotein G OS=Homo sapiens OX=9606 GN=SNRPG PE=1 SV=1 4.53 3974.9 - 337464 - - - -0.9458 - 1.527 0.12 - 135.2 1 2 0 -0.0014 13 0 0 0 0.00E+00 0.00E+00 - - - 1.0133 0.857 221125_WJC_METTL3_EV_vs_WT_F01.22218.22218.2 6.13 22-Jul K.DMPLIFIGGVPR[166.11].S "sp|O60507|TPST1_HUMAN,tr|C9J3I4|C9J3I4_HUMAN" 2 1323.7248 -1 9547 22218 2 1323.725726 662.8697 Protein-tyrosine sulfotransferase 1 OS=Homo sapiens OX=9606 GN=TPST1 PE=1 SV=1 5.84 3975.1 - 292899 - - - 0.6625 - 0.936 0.028 - 99.5 2 2 0 0.0009 12 0 0 0 0.00E+00 0.00E+00 - - - -1.061 0.9726 221125_WJC_METTL3_EV_vs_WT_F01.22220.22220.2 0.000305 16-Jun R.LFPPQWIC[160.03]C[160.03].D sp|Q86U44|MTA70_HUMAN 1 1219.5518 - 9548 22220 2 1219.553002 610.7832 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 5.51 3975.4 - 6.70E+06 - - - 0.9676 - 1.352 0.468 - 132.1 1 1 0 0.0012 9 0 0 0 - - - - - 3.3698 0.9998 221125_WJC_METTL3_EV_vs_WT_F01.22222.22222.2 0.004 13/22 K.AIIIFVPVPQLK.S "sp|P62081|RS7_HUMAN,tr|B5MCP9|B5MCP9_HUMAN" 2 1336.8482 0.83 9550 22222 2 1336.849374 669.4314 40S ribosomal protein S7 OS=Homo sapiens OX=9606 GN=RPS7 PE=1 SV=1 8.8 3975.6 - 3.84E+06 - - - 0.8445 - 2.376 0.395 - 599.9 1 2 0 0.0011 12 0 0 0 3.91E+07 4.69E+07 - - - 4.2352 0.9996 221125_WJC_METTL3_EV_vs_WT_F01.22224.22224.2 0.00503 16-Oct R.YLDVSILGK[136.11].F sp|Q86U44|MTA70_HUMAN 1 1014.5841 0.39 9552 22224 2 1014.584993 508.2993 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 5.83 3975.8 - 1.90E+06 - - - 0.8821 - 1.723 0.394 - 250 1 2 0 0.0009 9 0 0 0 3.81E+06 9.76E+06 - - - 3.5248 0.9997 221125_WJC_METTL3_EV_vs_WT_F01.22225.22225.2 0.00103 16-Oct R.FLFSLFGQK[136.11].H "sp|Q13155|AIMP2_HUMAN,tr|A8MU58|A8MU58_HUMAN" 2 1093.6052 -1 9553 22225 2 1093.60674 547.8099 Aminoacyl tRNA synthase complex-interacting multifunctional protein 2 OS=Homo sapiens OX=9606 GN=AIMP2 PE=1 SV=2 8.75 3975.9 - 1.58E+06 - - - 1.4384 - 1.783 0.452 - 243.4 1 2 0 0.0016 9 0 0 0 0.00E+00 0.00E+00 - - - 4.052 0.9987 221125_WJC_METTL3_EV_vs_WT_F01.22226.22226.2 0.0317 18-Oct K.LASDLLEWIR[166.11].R "sp|O43707|ACTN4_HUMAN,sp|P12814|ACTN1_HUMAN,tr|A0A804HK61|A0A804HK61_HUMAN,tr|G3V2W4|G3V2W4_HUMAN,tr|A0A804HJU8|A0A804HJU8_HUMAN,tr|H9KV75|H9KV75_HUMAN,tr|A0A804HLF4|A0A804HLF4_HUMAN,tr|A0A7I2V4Y4|A0A7I2V4Y4_HUMAN,tr|A0A804HII9|A0A804HII9_HUMAN,tr|A0A804HL31|A0A804HL31_HUMAN,tr|F5GXS2|F5GXS2_HUMAN,tr|A0A804HKE2|A0A804HKE2_HUMAN,tr|A0A804HLD0|A0A804HLD0_HUMAN,tr|H7C144|H7C144_HUMAN" 14 1224.6742 0.7 9554 22226 2 1224.673788 613.3444 Alpha-actinin-4 OS=Homo sapiens OX=9606 GN=ACTN4 PE=1 SV=2 4.37 3975.9 - 1.57E+06 - - - -0.3307 - 2.167 0.126 - 301.9 1 2 0 -0.0004 10 0 0 0 3.94E+06 5.62E+06 - - - 2.1301 0.9995 221125_WJC_METTL3_EV_vs_WT_F01.22230.22230.2 4.32E-05 28-Oct K.SVISGGLDALEFIGK[136.11].K "sp|Q9NRY5|F1142_HUMAN,tr|E7ESJ7|E7ESJ7_HUMAN,tr|E5RGF9|E5RGF9_HUMAN" 3 1512.8279 1.35 9558 22230 2 1512.82828 757.4212 Protein FAM114A2 OS=Homo sapiens OX=9606 GN=FAM114A2 PE=1 SV=4 4.37 3976.4 - 940411 - - - 0.2446 - 1.708 0.366 - 142.3 1 2 0 0.0004 15 0 0 0 5.05E+06 3.75E+06 - - - 3.0603 0.9999 221125_WJC_METTL3_EV_vs_WT_F01.22231.22231.2 1.35E-05 14/20 K.TLSYLLPLLQR[166.11].L sp|Q9NUL7|DDX28_HUMAN 1 1325.7946 0.89 9559 22231 2 1325.795722 663.9046 Probable ATP-dependent RNA helicase DDX28 OS=Homo sapiens OX=9606 GN=DDX28 PE=1 SV=2 8.41 3976.5 - 940331 - - - 0.8139 - 2.217 0.561 - 696.2 1 2 0 0.0011 11 0 0 0 3.06E+06 3.45E+06 - - - 5.338 0.9999 221125_WJC_METTL3_EV_vs_WT_F01.22233.22233.2 3.05E-06 20-Dec K.TLSYLLPLLQR.L sp|Q9NUL7|DDX28_HUMAN 1 1315.7864 -1 9561 22233 2 1315.786695 658.9005 Probable ATP-dependent RNA helicase DDX28 OS=Homo sapiens OX=9606 GN=DDX28 PE=1 SV=2 8.41 3976.7 - 867457 - - - 0.2447 - 1.992 0.571 - 444.4 1 2 0 0.0003 11 0 0 0 0.00E+00 0.00E+00 - - - 5.1226 0.8656 221125_WJC_METTL3_EV_vs_WT_F01.22234.22234.2 0.119 22-Aug R.SLLVIPNTLAVN.A "sp|P17987|TCPA_HUMAN,tr|F5H282|F5H282_HUMAN,tr|E7EQR6|E7EQR6_HUMAN" 3 1252.7391 - 9562 22234 2 1252.739994 627.3768 T-complex protein 1 subunit alpha OS=Homo sapiens OX=9606 GN=TCP1 PE=1 SV=1 5.24 3976.8 - 866979 - - - 0.7232 - 1.605 0.194 - 220.3 1 1 0 0.0009 12 0 0 0 - - - - - 1.7185 0.9999 221125_WJC_METTL3_EV_vs_WT_F01.22237.22237.2 0.000103 26-Nov R.ISLPLPNFSSLNLR.E "sp|P08670|VIME_HUMAN,tr|B0YJC4|B0YJC4_HUMAN" 2 1569.8879 1.76 9565 22237 2 1569.887227 785.9512 Vimentin OS=Homo sapiens OX=9606 GN=VIM PE=1 SV=4 9.75 3977.2 - 614677 - - - -0.4147 - 2.012 0.532 - 260.5 1 2 0 -0.0007 14 0 0 0 7.87E+07 4.47E+07 - - - 4.7246 0.9999 221125_WJC_METTL3_EV_vs_WT_F01.22247.22247.3 1.16E-05 14/44 K.AIIIFVPVPQLK[136.11].S "sp|P62081|RS7_HUMAN,tr|B5MCP9|B5MCP9_HUMAN" 2 1344.8624 0.92 9574 22247 3 1344.860434 449.2948 40S ribosomal protein S7 OS=Homo sapiens OX=9606 GN=RPS7 PE=1 SV=1 8.8 3978.2 - 1.29E+06 - - - -1.4953 - 2.351 0.45 - 266.6 1 2 0 -0.002 12 0 0 0 3.06E+06 3.34E+06 - - - 5.926 0.9999 221125_WJC_METTL3_EV_vs_WT_F01.22248.22248.3 0.0112 14/44 K.AIIIFVPVPQLK.S "sp|P62081|RS7_HUMAN,tr|B5MCP9|B5MCP9_HUMAN" 2 1336.8482 0.92 9575 22248 3 1336.846658 446.6234 40S ribosomal protein S7 OS=Homo sapiens OX=9606 GN=RPS7 PE=1 SV=1 8.8 3978.3 - 1.17E+06 - - - -1.1871 - 2.294 0.396 - 270 1 2 0 -0.0016 12 0 0 0 3.06E+06 3.34E+06 - - - 5.256 0.9448 221125_WJC_METTL3_EV_vs_WT_F01.22250.22250.2 0.018 22-Sep R.ISLGLPVGAVIN.C "sp|P62829|RL23_HUMAN,tr|J3KT29|J3KT29_HUMAN,tr|B9ZVP7|B9ZVP7_HUMAN,tr|C9JD32|C9JD32_HUMAN" 4 1151.6914 - 9577 22250 2 1151.690665 576.853 60S ribosomal protein L23 OS=Homo sapiens OX=9606 GN=RPL23 PE=1 SV=1 5.52 3978.5 - 965701 - - - -0.6469 - 1.735 0.265 - 148.3 1 1 0 -0.0007 12 0 0 0 - - - - - 2.4479 0.9996 221125_WJC_METTL3_EV_vs_WT_F01.22254.22254.2 0.00419 26-Dec R.ISLPLPNFSSLNLR[166.11].E "sp|P08670|VIME_HUMAN,tr|B0YJC4|B0YJC4_HUMAN" 2 1579.8961 1.99 9581 22254 2 1579.892666 790.9554 Vimentin OS=Homo sapiens OX=9606 GN=VIM PE=1 SV=4 9.75 3978.9 - 493806 - - - -2.2039 - 2.265 0.455 - 346.2 1 2 0 -0.0035 14 0 0 0 7.87E+07 3.96E+07 - - - 4.4522 0.9978 221125_WJC_METTL3_EV_vs_WT_F01.22256.22256.3 0.0753 Sep-60 K.LPIVNEDDELVAIIAR[166.11].T "sp|P12268|IMDH2_HUMAN,tr|A0A7I2YQK5|A0A7I2YQK5_HUMAN,tr|H0Y4R1|H0Y4R1_HUMAN,tr|A0A7I2V2T3|A0A7I2V2T3_HUMAN,tr|E7ETK5|E7ETK5_HUMAN" 5 1788.9861 -1 9583 22256 3 1788.983574 597.336 Inosine-5'-monophosphate dehydrogenase 2 OS=Homo sapiens OX=9606 GN=IMPDH2 PE=1 SV=2 3.92 3979.2 - 442507 - - - -1.4036 - 1.814 0.255 - 131.9 1 2 0 -0.0025 16 0 0 0 0.00E+00 0.00E+00 - - - 2.9104 0.9987 221125_WJC_METTL3_EV_vs_WT_F01.22259.22259.2 0.217 30-May K.LPIVNEDDELVAIIAR.T "sp|P12268|IMDH2_HUMAN,tr|A0A7I2YQK5|A0A7I2YQK5_HUMAN,tr|H0Y4R1|H0Y4R1_HUMAN,tr|A0A7I2V2T3|A0A7I2V2T3_HUMAN,tr|E7ETK5|E7ETK5_HUMAN" 5 1778.9778 -1 9586 22259 2 1778.976206 890.4962 Inosine-5'-monophosphate dehydrogenase 2 OS=Homo sapiens OX=9606 GN=IMPDH2 PE=1 SV=2 3.92 3979.6 - 364065 - - - -0.9045 - 1.64 0.299 - 59.8 3 2 0 -0.0016 16 0 0 0 0.00E+00 0.00E+00 - - - 2.252 0.8468 221125_WJC_METTL3_EV_vs_WT_F01.22262.22262.2 0.134 14/28 R.LPFLSSSNLSLDVLR.G "sp|Q9Y244|POMP_HUMAN,tr|A0A1W2PS02|A0A1W2PS02_HUMAN" 2 1659.9196 -1 9588 22262 2 1661.924408 830.9671 Proteasome maturation protein OS=Homo sapiens OX=9606 GN=POMP PE=1 SV=1 5.84 3979.9 - 528696 - - - 1207.791 - 2.722 0.332 - 465.6 1 2 0 2.0048 15 0 0 0 0.00E+00 0.00E+00 - - - 3.3255 0.9998 221125_WJC_METTL3_EV_vs_WT_F01.22263.22263.2 1.11E-05 14/28 K.GVFVQSVLPYFVATK.L "sp|Q53GQ0|DHB12_HUMAN,tr|A0A1B0GV93|A0A1B0GV93_HUMAN" 2 1653.913 -1 9589 22263 2 1653.910246 827.9638 Very-long-chain 3-oxoacyl-CoA reductase OS=Homo sapiens OX=9606 GN=HSD17B12 PE=1 SV=2 8.59 3980.1 - 346372 - - - -1.6833 - 2.284 0.507 - 461.8 1 2 0 -0.0028 15 0 0 0 0.00E+00 0.00E+00 - - - 4.8154 0.837 221125_WJC_METTL3_EV_vs_WT_F01.22264.22264.2 0.908 18-Sep K.VSQEILELLN.T "sp|Q86U44|MTA70_HUMAN,tr|H0YFV6|H0YFV6_HUMAN" 2 1156.634 - 9590 22264 2 1156.634673 579.3243 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 3.79 3980.1 - 9.07E+06 - - - 0.6216 - 1.712 0.132 - 227.5 1 1 0 0.0007 10 0 0 0 - - - - - 1.5165 1 221125_WJC_METTL3_EV_vs_WT_F01.22265.22265.2 2.30E-07 14/22 K.TSDLIVLGLPWK[136.11].T "sp|Q13148|TADBP_HUMAN,tr|A0A087WX29|A0A087WX29_HUMAN,tr|G3V162|G3V162_HUMAN,tr|A0A087WV68|A0A087WV68_HUMAN,tr|A0A087WYY0|A0A087WYY0_HUMAN,tr|K7EN94|K7EN94_HUMAN,tr|A0A0A0N0M3|A0A0A0N0M3_HUMAN,tr|B1AKP7|B1AKP7_HUMAN,tr|K7EJM5|K7EJM5_HUMAN,tr|A0A087WXQ5|A0A087WXQ5_HUMAN,tr|A0A087X260|A0A087X260_HUMAN" 11 1348.7846 -1 9591 22265 2 1348.785026 675.3996 TAR DNA-binding protein 43 OS=Homo sapiens OX=9606 GN=TARDBP PE=1 SV=1 5.5 3980.1 - 4.36E+06 - - - 0.3247 - 2.783 0.596 - 656.1 1 2 0 0.0004 12 0 0 0 0.00E+00 0.00E+00 - - - 6.136 1 221125_WJC_METTL3_EV_vs_WT_F01.22266.22266.2 0.00018 14/22 R.NLQNLLILTAIK[136.11].A "sp|Q00610|CLH1_HUMAN,sp|P53675|CLH2_HUMAN,tr|A0A087WVQ6|A0A087WVQ6_HUMAN,tr|A0A087WX41|A0A087WX41_HUMAN" 4 1360.8533 -1 9592 22266 2 1360.852968 681.4339 Clathrin heavy chain 1 OS=Homo sapiens OX=9606 GN=CLTC PE=1 SV=5 8.75 3980.2 - 2.29E+06 - - - -0.2712 - 2.56 0.576 - 619.9 1 2 0 -0.0004 12 0 0 0 0.00E+00 0.00E+00 - - - 5.7685 1 221125_WJC_METTL3_EV_vs_WT_F01.22267.22267.2 1.40E-05 13/22 R.YLDFSSIITEVR.A sp|Q8N1N4|K2C78_HUMAN 1 1441.7453 -1 9593 22267 2 1441.747705 721.8799 "Keratin, type II cytoskeletal 78 OS=Homo sapiens OX=9606 GN=KRT78 PE=1 SV=2" 4.37 3980.3 - 1.93E+06 - - - 1.6709 - 2.606 0.601 - 575.3 1 2 0 0.0024 12 0 0 0 0.00E+00 0.00E+00 - - - 5.9994 0.9959 221125_WJC_METTL3_EV_vs_WT_F01.22268.22268.2 0.000164 18-Sep K.FDTIYQILLK.K "sp|Q14258|TRI25_HUMAN,tr|A0A3B3IUA7|A0A3B3IUA7_HUMAN" 2 1252.7067 -1 9594 22268 2 1252.712463 627.3606 E3 ubiquitin\ISG15 ligase TRIM25 OS=Homo sapiens OX=9606 GN=TRIM25 PE=1 SV=2 5.83 3980.4 - 1.25E+06 - - - 4.5805 - 1.859 0.389 - 235.7 1 2 0 0.0057 10 0 0 0 0.00E+00 0.00E+00 - - - 3.6431 0.8322 221125_WJC_METTL3_EV_vs_WT_F01.22269.22269.2 2.88 26-Jun R.KGEEDGLHVGLDER[166.11].R "sp|O15090|ZN536_HUMAN,tr|K7EKT4|K7EKT4_HUMAN" 2 1562.7564 - 9595 22269 2 1562.749099 782.3855 Zinc finger protein 536 OS=Homo sapiens OX=9606 GN=ZNF536 PE=1 SV=3 4.5 3980.5 - 1.25E+06 - - - -4.684 - 1.163 0.139 - 77.9 1 2 0 -0.0073 14 0 0 0 - - - - - 0.4443 0.9999 221125_WJC_METTL3_EV_vs_WT_F01.22270.22270.2 0.000861 22-Nov K.LGTLSALDILIK[136.11].N "sp|Q86VP6|CAND1_HUMAN,tr|A0A0C4DGH5|A0A0C4DGH5_HUMAN" 2 1263.7893 -1 9596 22270 2 1263.789568 632.9019 Cullin-associated NEDD8-dissociated protein 1 OS=Homo sapiens OX=9606 GN=CAND1 PE=1 SV=2 5.84 3980.6 - 1.14E+06 - - - 0.1812 - 2.498 0.525 - 418.3 1 2 0 0.0002 12 0 0 0 0.00E+00 0.00E+00 - - - 5.3274 0.9643 221125_WJC_METTL3_EV_vs_WT_F01.22271.22271.2 0.0015 18-Jul K.VDIVAINDPF.L sp|P04406|G3P_HUMAN 1 1101.5706 - 9597 22271 2 1101.571445 551.7926 Glyceraldehyde-3-phosphate dehydrogenase OS=Homo sapiens OX=9606 GN=GAPDH PE=1 SV=3 3.56 3980.7 - 1.06E+06 - - - 0.7435 - 1.319 0.429 - 155.4 1 1 0 0.0008 10 0 0 0 - - - - - 2.9822 0.989 221125_WJC_METTL3_EV_vs_WT_F01.22273.22273.2 2.76E-05 14/26 K.AGVMALANLLQIQR[166.11].H "sp|Q9Y224|RTRAF_HUMAN,tr|G3V4C6|G3V4C6_HUMAN,tr|H0YJB9|H0YJB9_HUMAN" 3 1506.858 -1 9599 22273 2 1506.868379 754.4363 "RNA transcription, translation and transport factor protein OS=Homo sapiens OX=9606 GN=RTRAF PE=1 SV=1" 9.79 3980.9 - 936716 - - - 6.8958 - 2.59 0.393 - 419.9 1 2 0 0.0104 14 0 0 0 0.00E+00 0.00E+00 - - - 4.3286 1 221125_WJC_METTL3_EV_vs_WT_F01.22275.22275.3 6.49E-06 Dec-52 R.ISLPLPNFSSLNLR.E "sp|P08670|VIME_HUMAN,tr|B0YJC4|B0YJC4_HUMAN" 2 1569.8879 1.25 9601 22275 3 1569.887957 524.3032 Vimentin OS=Homo sapiens OX=9606 GN=VIM PE=1 SV=4 9.75 3981.2 - 516513 - - - 0.0503 - 2.486 0.535 - 196 1 2 0 0.0001 14 0 0 0 1.62E+07 1.29E+07 - - - 6.9248 0.9997 221125_WJC_METTL3_EV_vs_WT_F01.22276.22276.2 7.07E-07 18-Sep R.SPNDLLALFR.Y "sp|Q92626|PXDN_HUMAN,tr|H7C1W1|H7C1W1_HUMAN" 2 1144.6241 -1 9602 22276 2 1144.62514 573.3193 Peroxidasin homolog OS=Homo sapiens OX=9606 GN=PXDN PE=1 SV=2 5.55 3981.3 - 406430 - - - 0.9453 - 1.974 0.431 - 223.8 1 2 0 0.0011 10 0 0 0 0.00E+00 0.00E+00 - - - 4.1223 0.9998 221125_WJC_METTL3_EV_vs_WT_F01.22279.22279.3 0.000438 Nov-52 R.ISLPLPNFSSLNLR[166.11].E "sp|P08670|VIME_HUMAN,tr|B0YJC4|B0YJC4_HUMAN" 2 1579.8961 2.03 9605 22279 3 1579.899529 527.6393 Vimentin OS=Homo sapiens OX=9606 GN=VIM PE=1 SV=4 9.75 3981.7 - 366106 - - - 2.14 - 2.113 0.428 - 127.3 1 2 0 0.0034 14 0 0 0 1.73E+07 8.51E+06 - - - 5.299 0.9538 221125_WJC_METTL3_EV_vs_WT_F01.22280.22280.3 0.311 Jun-44 R.YLDFSSIITEVR.A sp|Q8N1N4|K2C78_HUMAN 1 1441.7453 35.99 9606 22280 3 1441.747245 481.589 "Keratin, type II cytoskeletal 78 OS=Homo sapiens OX=9606 GN=KRT78 PE=1 SV=2" 4.37 3981.8 - 364522 - - - 1.3518 - 1.341 0.153 - 66.5 1 2 0 0.0019 12 0 0 0 9.50E+05 2.64E+04 - - - 1.0586 1 221125_WJC_METTL3_EV_vs_WT_F01.22285.22285.2 5.37E-11 15/22 K.TSDLIVLGLPWK.T "sp|Q13148|TADBP_HUMAN,tr|A0A087WX29|A0A087WX29_HUMAN,tr|G3V162|G3V162_HUMAN,tr|A0A087WV68|A0A087WV68_HUMAN,tr|A0A087WYY0|A0A087WYY0_HUMAN,tr|K7EN94|K7EN94_HUMAN,tr|A0A0A0N0M3|A0A0A0N0M3_HUMAN,tr|B1AKP7|B1AKP7_HUMAN,tr|K7EJM5|K7EJM5_HUMAN,tr|A0A087WXQ5|A0A087WXQ5_HUMAN,tr|A0A087X260|A0A087X260_HUMAN" 11 1340.7704 -1 9610 22285 2 1340.77086 671.3925 TAR DNA-binding protein 43 OS=Homo sapiens OX=9606 GN=TARDBP PE=1 SV=1 5.5 3982.4 - 2.76E+07 - - - 0.352 - 2.973 0.626 - 816.5 1 2 0 0.0005 12 0 0 0 0.00E+00 0.00E+00 - - - 6.5313 1 221125_WJC_METTL3_EV_vs_WT_F01.22286.22286.3 2.48E-06 Dec-48 K.LFYADHPFIFLVR.D "sp|P50454|SERPH_HUMAN,tr|E9PKH2|E9PKH2_HUMAN,tr|H0YEP8|H0YEP8_HUMAN" 3 1636.8766 -1 9611 22286 3 1636.876603 546.6328 Serpin H1 OS=Homo sapiens OX=9606 GN=SERPINH1 PE=1 SV=2 6.74 3982.5 - 2.74E+06 - - - 0.011 - 2.549 0.517 - 141.2 1 2 0 0 13 0 0 0 0.00E+00 0.00E+00 - - - 6.841 1 221125_WJC_METTL3_EV_vs_WT_F01.22287.22287.2 0.000116 17/28 R.LPFLSSSNLSLDVLR.G "sp|Q9Y244|POMP_HUMAN,tr|A0A1W2PS02|A0A1W2PS02_HUMAN" 2 1659.9196 -1 9612 22287 2 1659.91821 830.9671 Proteasome maturation protein OS=Homo sapiens OX=9606 GN=POMP PE=1 SV=1 5.84 3982.6 - 2.46E+06 - - - -0.8205 - 3.397 0.548 - 875 1 2 0 -0.0014 15 0 0 0 0.00E+00 0.00E+00 - - - 6.0946 0.9999 221125_WJC_METTL3_EV_vs_WT_F01.22288.22288.2 5.55E-05 13/22 K.SVEELLEAELLK.V "sp|Q86UP2|KTN1_HUMAN,tr|G3V4Y7|G3V4Y7_HUMAN,tr|G3V5G2|G3V5G2_HUMAN,tr|H0YJZ8|H0YJZ8_HUMAN" 4 1371.7497 -1 9613 22288 2 1371.748903 686.8821 Kinectin OS=Homo sapiens OX=9606 GN=KTN1 PE=1 SV=1 4.09 3982.7 - 1.67E+06 - - - -0.5905 - 2.678 0.466 - 454.3 1 2 0 -0.0008 12 0 0 0 0.00E+00 0.00E+00 - - - 5.0745 1 221125_WJC_METTL3_EV_vs_WT_F01.22289.22289.2 1.16E-10 17/28 R.LPFLSSSNLSLDVLR[166.11].G "sp|Q9Y244|POMP_HUMAN,tr|A0A1W2PS02|A0A1W2PS02_HUMAN" 2 1669.9278 -1 9614 22289 2 1669.924995 835.9712 Proteasome maturation protein OS=Homo sapiens OX=9606 GN=POMP PE=1 SV=1 5.84 3982.7 - 1.21E+06 - - - -1.7049 - 3.462 0.672 - 1201.2 1 2 0 -0.0028 15 0 0 0 0.00E+00 0.00E+00 - - - 7.0566 0.7822 221125_WJC_METTL3_EV_vs_WT_F01.22290.22290.2 0.381 16-Jul R.KPEVC[160.03]VMER[166.11].R "sp|Q6IE36|OVOS2_HUMAN,tr|A0A0G2JMS6|A0A0G2JMS6_HUMAN" 2 1156.5608 - 9615 22290 2 1156.570621 579.2877 Ovostatin homolog 2 OS=Homo sapiens OX=9606 GN=OVOS2 PE=2 SV=2 6.14 3982.8 - 1.18E+06 - - - 8.4743 - 1.573 0.18 - 114.6 1 2 0 0.0098 9 0 0 0 - - - - - 1.6779 0.9999 221125_WJC_METTL3_EV_vs_WT_F01.22291.22291.2 1.90E-06 13/22 K.SVEELLEAELLK[136.11].V "sp|Q86UP2|KTN1_HUMAN,tr|G3V4Y7|G3V4Y7_HUMAN,tr|G3V5G2|G3V5G2_HUMAN,tr|H0YJZ8|H0YJZ8_HUMAN" 4 1379.7639 -1 9616 22291 2 1379.764589 690.8892 Kinectin OS=Homo sapiens OX=9606 GN=KTN1 PE=1 SV=1 4.09 3982.9 - 1.10E+06 - - - 0.4899 - 2.726 0.514 - 478.5 1 2 0 0.0007 12 0 0 0 0.00E+00 0.00E+00 - - - 5.4758 1 221125_WJC_METTL3_EV_vs_WT_F01.22292.22292.3 7.71E-11 23/76 K.MLLDPMGGIVMTNDGNAILR[166.11].E "sp|P49368|TCPG_HUMAN,tr|E9PRC8|E9PRC8_HUMAN,tr|B4DUR8|B4DUR8_HUMAN,tr|Q5SZX9|Q5SZX9_HUMAN,tr|Q5SZX6|Q5SZX6_HUMAN" 5 2140.0718 -1 9617 22292 3 2140.071314 714.3646 T-complex protein 1 subunit gamma OS=Homo sapiens OX=9606 GN=CCT3 PE=1 SV=4 4.21 3983 - 1.08E+06 - - - -0.2374 - 3.96 0.637 - 735.4 1 2 0 -0.0005 20 0 0 0 0.00E+00 0.00E+00 - - - 8.9806 1 221125_WJC_METTL3_EV_vs_WT_F01.22294.22294.3 4.19E-06 Oct-44 K.TSDLIVLGLPWK.T "sp|Q13148|TADBP_HUMAN,tr|A0A087WX29|A0A087WX29_HUMAN,tr|G3V162|G3V162_HUMAN,tr|A0A087WV68|A0A087WV68_HUMAN,tr|A0A087WYY0|A0A087WYY0_HUMAN,tr|K7EN94|K7EN94_HUMAN,tr|A0A0A0N0M3|A0A0A0N0M3_HUMAN,tr|B1AKP7|B1AKP7_HUMAN,tr|K7EJM5|K7EJM5_HUMAN,tr|A0A087WXQ5|A0A087WXQ5_HUMAN,tr|A0A087X260|A0A087X260_HUMAN" 11 1340.7704 -1 9619 22294 3 1340.77016 447.9307 TAR DNA-binding protein 43 OS=Homo sapiens OX=9606 GN=TARDBP PE=1 SV=1 5.5 3983.3 - 909863 - - - -0.1701 - 1.892 0.56 - 189.2 1 2 0 -0.0002 12 0 0 0 0.00E+00 0.00E+00 - - - 6.5508 1 221125_WJC_METTL3_EV_vs_WT_F01.22296.22296.2 9.62E-08 18/26 R.VISGVLQLGNIVFK.K sp|P35579|MYH9_HUMAN 1 1485.8919 -1 9621 22296 2 1485.890982 743.9532 Myosin-9 OS=Homo sapiens OX=9606 GN=MYH9 PE=1 SV=4 8.72 3983.5 - 854964 - - - -0.6185 - 3.042 0.624 - 917.6 1 2 0 -0.0009 14 0 0 0 0.00E+00 0.00E+00 - - - 6.4414 0.993 221125_WJC_METTL3_EV_vs_WT_F01.22298.22298.2 8.26E-05 Dec-36 K.IFVGNVDGADTTPEELAAL.F "sp|Q96PK6|RBM14_HUMAN,tr|B8ZZ74|B8ZZ74_HUMAN,tr|F8WDX3|F8WDX3_HUMAN,tr|A0A0A0MSL8|A0A0A0MSL8_HUMAN,tr|A0A0A6YYI9|A0A0A6YYI9_HUMAN" 5 1930.9524 - 9623 22298 2 1930.951174 966.4835 RNA-binding protein 14 OS=Homo sapiens OX=9606 GN=RBM14 PE=1 SV=2 3.43 3983.8 - 627221 - - - -0.6287 - 2.096 0.564 - 142.1 1 1 0 -0.0012 19 0 0 0 - - - - - 5.0257 0.9996 221125_WJC_METTL3_EV_vs_WT_F01.22299.22299.3 0.000359 Sep-44 K.TSDLIVLGLPWK[136.11].T "sp|Q13148|TADBP_HUMAN,tr|A0A087WX29|A0A087WX29_HUMAN,tr|G3V162|G3V162_HUMAN,tr|A0A087WV68|A0A087WV68_HUMAN,tr|A0A087WYY0|A0A087WYY0_HUMAN,tr|K7EN94|K7EN94_HUMAN,tr|A0A0A0N0M3|A0A0A0N0M3_HUMAN,tr|B1AKP7|B1AKP7_HUMAN,tr|K7EJM5|K7EJM5_HUMAN,tr|A0A087WXQ5|A0A087WXQ5_HUMAN,tr|A0A087X260|A0A087X260_HUMAN" 11 1348.7846 -1 9624 22299 3 1348.78357 450.6021 TAR DNA-binding protein 43 OS=Homo sapiens OX=9606 GN=TARDBP PE=1 SV=1 5.5 3983.9 - 591947 - - - -0.7548 - 1.728 0.354 - 126.9 1 2 0 -0.001 12 0 0 0 0.00E+00 0.00E+00 - - - 4.0026 0.9978 221125_WJC_METTL3_EV_vs_WT_F01.22302.22302.2 0.000214 24-Oct R.DPTYFGPVLNYLR.H "sp|Q9NXV2|KCTD5_HUMAN,tr|H3BSS5|H3BSS5_HUMAN" 2 1553.7878 4.53 9627 22302 2 1553.782083 777.9012 BTB\POZ domain-containing protein KCTD5 OS=Homo sapiens OX=9606 GN=KCTD5 PE=1 SV=1 5.83 3984.3 - 415644 - - - -3.6981 - 1.902 0.395 - 315.8 1 2 0 -0.0057 13 0 0 0 1.08E+07 2.38E+06 - - - 3.6067 0.9849 221125_WJC_METTL3_EV_vs_WT_F01.22306.22306.2 0.707 18-May R.NMQDVVEDFK.V sp|O95678|K2C75_HUMAN 1 1223.5492 56.45 9630 22306 2 1223.550157 612.7819 "Keratin, type II cytoskeletal 75 OS=Homo sapiens OX=9606 GN=KRT75 PE=1 SV=2" 4.03 3984.7 - 6.89E+06 - - - 0.7503 - 1.122 0.148 - 95.6 1 2 0 0.0009 10 0 0 0 1.60E+07 2.84E+05 - - - 0.4552 1 221125_WJC_METTL3_EV_vs_WT_F01.22307.22307.2 1.83E-09 16/30 K.VGEVTYVELLMDAEGK.S "sp|P52272|HNRPM_HUMAN,tr|M0R019|M0R019_HUMAN,tr|M0R0N3|M0R0N3_HUMAN,tr|A0A087X0X3|A0A087X0X3_HUMAN,tr|M0R2T0|M0R2T0_HUMAN" 5 1751.8652 -1 9631 22307 2 1751.865245 876.9399 Heterogeneous nuclear ribonucleoprotein M OS=Homo sapiens OX=9606 GN=HNRNPM PE=1 SV=3 4 3984.7 - 3.79E+06 - - - 0.0525 - 3.261 0.654 - 746.1 1 2 0 0.0001 16 0 0 0 0.00E+00 0.00E+00 - - - 6.7775 1 221125_WJC_METTL3_EV_vs_WT_F01.22308.22308.3 7.07E-07 15/60 K.VGEVTYVELLMDAEGK.S "sp|P52272|HNRPM_HUMAN,tr|M0R019|M0R019_HUMAN,tr|M0R0N3|M0R0N3_HUMAN,tr|A0A087X0X3|A0A087X0X3_HUMAN,tr|M0R2T0|M0R2T0_HUMAN" 5 1751.8652 -1 9632 22308 3 1751.866928 584.9623 Heterogeneous nuclear ribonucleoprotein M OS=Homo sapiens OX=9606 GN=HNRNPM PE=1 SV=3 4 3984.8 - 2.59E+06 - - - 1.0132 - 2.786 0.536 - 308.6 1 2 0 0.0018 16 0 0 0 0.00E+00 0.00E+00 - - - 7.1444 0.9998 221125_WJC_METTL3_EV_vs_WT_F01.22310.22310.2 0.00168 22-Nov R.SLLEPFVYLASK.M "sp|Q9NYR9|KBRS2_HUMAN,tr|K7ERG2|K7ERG2_HUMAN,tr|H7BXP1|H7BXP1_HUMAN" 3 1365.7544 -1 9634 22310 2 1365.754972 683.8845 NF-kappa-B inhibitor-interacting Ras-like protein 2 OS=Homo sapiens OX=9606 GN=NKIRAS2 PE=1 SV=1 5.72 3985 - 1.23E+06 - - - 0.4159 - 2.228 0.418 - 356.8 1 2 0 0.0006 12 0 0 0 0.00E+00 0.00E+00 - - - 4.236 0.9991 221125_WJC_METTL3_EV_vs_WT_F01.22313.22313.2 0.0979 16-Sep K.LLLPWLEAR.L "sp|Q00610|CLH1_HUMAN,tr|A0A087WVQ6|A0A087WVQ6_HUMAN" 2 1109.6597 -1 9637 22313 2 1109.660626 555.8371 Clathrin heavy chain 1 OS=Homo sapiens OX=9606 GN=CLTC PE=1 SV=5 6 3985.4 - 591745 - - - 0.8201 - 1.715 0.275 - 356.5 1 2 0 0.0009 9 0 0 0 0.00E+00 0.00E+00 - - - 2.6324 0.9998 221125_WJC_METTL3_EV_vs_WT_F01.22316.22316.2 6.90E-06 24-Dec R.AIAYLFPSGLFEK[136.11].R sp|P82933|RT09_HUMAN 1 1462.7952 0.99 9640 22316 2 1462.796121 732.4049 "28S ribosomal protein S9, mitochondrial OS=Homo sapiens OX=9606 GN=MRPS9 PE=1 SV=2" 6.05 3985.8 - 532609 - - - 0.6617 - 2.72 0.356 - 555.1 1 2 0 0.001 13 0 0 0 3.23E+06 3.25E+06 - - - 4.2383 0.9999 221125_WJC_METTL3_EV_vs_WT_F01.22329.22329.2 5.88E-06 18-Nov R.C[160.03]WAGSLWLFK.D sp|Q9BQA1|MEP50_HUMAN 1 1266.6219 -1 9652 22329 2 1266.623021 634.3183 Methylosome protein 50 OS=Homo sapiens OX=9606 GN=WDR77 PE=1 SV=1 8.22 3987.1 - 4.82E+06 - - - 0.8456 - 2.138 0.543 - 378.9 1 2 0 0.0011 10 0 0 0 0.00E+00 0.00E+00 - - - 5.1723 1 221125_WJC_METTL3_EV_vs_WT_F01.22330.22330.2 5.82E-10 14/22 K.FFDDPMLLELAK.Q "sp|Q15029|U5S1_HUMAN,tr|K7EP67|K7EP67_HUMAN" 2 1437.7214 -1 9653 22330 2 1437.722362 719.868 116 kDa U5 small nuclear ribonucleoprotein component OS=Homo sapiens OX=9606 GN=EFTUD2 PE=1 SV=1 4.03 3987.2 - 2.17E+06 - - - 0.6768 - 2.743 0.653 - 365.4 1 2 0 0.001 12 0 0 0 0.00E+00 0.00E+00 - - - 6.5187 0.9999 221125_WJC_METTL3_EV_vs_WT_F01.22331.22331.2 0.000115 18-Nov R.C[160.03]WAGSLWLFK[136.11].D sp|Q9BQA1|MEP50_HUMAN 1 1274.6362 -1 9654 22331 2 1274.636988 638.3254 Methylosome protein 50 OS=Homo sapiens OX=9606 GN=WDR77 PE=1 SV=1 8.22 3987.3 - 2.02E+06 - - - 0.6574 - 2.145 0.54 - 382.9 1 2 0 0.0008 10 0 0 0 0.00E+00 0.00E+00 - - - 5.1593 0.9681 221125_WJC_METTL3_EV_vs_WT_F01.22332.22332.2 0.00202 18-Jul K.VEDLTFTSPF.C "sp|Q99873|ANM1_HUMAN,tr|E9PKG1|E9PKG1_HUMAN" 2 1154.5496 - 9655 22332 2 1154.550584 578.2821 Protein arginine N-methyltransferase 1 OS=Homo sapiens OX=9606 GN=PRMT1 PE=1 SV=3 3.67 3987.4 - 1.70E+06 - - - 0.8904 - 1.405 0.43 - 136.1 1 1 0 0.001 10 0 0 0 - - - - - 3.1658 1 221125_WJC_METTL3_EV_vs_WT_F01.22333.22333.3 2.69E-06 13/64 R.AFLQGGQEATDIALLLR.D "sp|Q14203|DCTN1_HUMAN,tr|A0A804CDA6|A0A804CDA6_HUMAN,tr|E7EX90|E7EX90_HUMAN,tr|A0A7P0Z4C3|A0A7P0Z4C3_HUMAN,tr|Q6AWB1|Q6AWB1_HUMAN" 5 1814.989 -1 9656 22333 3 1814.991787 606.0036 Dynactin subunit 1 OS=Homo sapiens OX=9606 GN=DCTN1 PE=1 SV=3 4.37 3987.4 - 1.63E+06 - - - 1.5091 - 3.021 0.506 - 235.8 1 2 0 0.0027 17 0 0 0 0.00E+00 0.00E+00 - - - 6.9737 0.7936 221125_WJC_METTL3_EV_vs_WT_F01.22334.22334.2 0.0857 18-Sep N.ANIPSVSLSK[136.11].R "sp|P32019|I5P2_HUMAN,tr|E7ESY0|E7ESY0_HUMAN" 2 1022.5852 -1 9657 22334 2 1022.586042 512.2999 "Type II inositol 1,4,5-trisphosphate 5-phosphatase OS=Homo sapiens OX=9606 GN=INPP5B PE=1 SV=4" 8.8 3987.6 - 1.14E+06 - - - 0.8625 - 1.749 0.104 - 154.1 1 1 0 0.0009 10 0 0 0 0.00E+00 0.00E+00 - - - 1.3693 1 221125_WJC_METTL3_EV_vs_WT_F01.22335.22335.2 7.25E-10 20/32 R.AFLQGGQEATDIALLLR.D "sp|Q14203|DCTN1_HUMAN,tr|A0A804CDA6|A0A804CDA6_HUMAN,tr|E7EX90|E7EX90_HUMAN,tr|A0A7P0Z4C3|A0A7P0Z4C3_HUMAN,tr|Q6AWB1|Q6AWB1_HUMAN" 5 1814.989 -1 9658 22335 2 1814.991085 908.5018 Dynactin subunit 1 OS=Homo sapiens OX=9606 GN=DCTN1 PE=1 SV=3 4.37 3987.7 - 1.00E+06 - - - 1.1223 - 3.836 0.686 - 1349.7 1 2 0 0.002 17 0 0 0 0.00E+00 0.00E+00 - - - 7.4125 0.9998 221125_WJC_METTL3_EV_vs_WT_F01.22337.22337.2 0.0021 22-Oct R.SQALIEELLLYK.R sp|Q5VT52|RPRD2_HUMAN 1 1418.8021 -1 9660 22337 2 1418.803417 710.4083 Regulation of nuclear pre-mRNA domain-containing protein 2 OS=Homo sapiens OX=9606 GN=RPRD2 PE=1 SV=1 4.53 3987.9 - 933108 - - - 0.9409 - 2.22 0.413 - 299.8 1 2 0 0.0013 12 0 0 0 0.00E+00 0.00E+00 - - - 4.1894 0.9998 221125_WJC_METTL3_EV_vs_WT_F01.22347.22347.2 2.91E-06 Aug-32 R.AFLQGGQEATDIALLLR[166.11].D "sp|Q14203|DCTN1_HUMAN,tr|A0A804CDA6|A0A804CDA6_HUMAN,tr|E7EX90|E7EX90_HUMAN,tr|A0A7P0Z4C3|A0A7P0Z4C3_HUMAN,tr|Q6AWB1|Q6AWB1_HUMAN" 5 1824.9973 -1 9669 22347 2 1824.996641 913.5059 Dynactin subunit 1 OS=Homo sapiens OX=9606 GN=DCTN1 PE=1 SV=3 4.37 3989.1 - 87821.3 - - - -0.371 - 1.584 0.564 - 111.8 1 2 0 -0.0007 17 0 0 0 0.00E+00 0.00E+00 - - - 4.3373 0.7664 221125_WJC_METTL3_EV_vs_WT_F01.22350.22350.2 0.203 16-Jul K.R[166.11]PPSAFFLF.C "sp|B2RPK0|HGB1A_HUMAN,sp|P26583|HMGB2_HUMAN,sp|P09429|HMGB1_HUMAN,tr|D6R9A6|D6R9A6_HUMAN,tr|Q5T7C4|Q5T7C4_HUMAN" 5 1090.5839 0.19 9672 22350 2 1090.585492 546.2992 Putative high mobility group protein B1-like 1 OS=Homo sapiens OX=9606 GN=HMGB1P1 PE=5 SV=1 9.75 3989.3 - 1.80E+06 - - - 1.4396 - 1.302 0.225 - 142.8 1 1 0 0.0016 9 0 0 0 1.21E+06 6.48E+06 - - - 1.4658 0.9945 221125_WJC_METTL3_EV_vs_WT_F01.22351.22351.2 4.47E-07 22-Oct K.NTPFLYDLVMTH.A "sp|Q09028|RBBP4_HUMAN,sp|Q16576|RBBP7_HUMAN,tr|E9PIC4|E9PIC4_HUMAN,tr|E9PNS2|E9PNS2_HUMAN,tr|E9PNS6|E9PNS6_HUMAN,tr|C9JAJ9|C9JAJ9_HUMAN,tr|E9PC52|E9PC52_HUMAN" 7 1449.6962 - 9673 22351 2 1449.696276 725.8554 Histone-binding protein RBBP4 OS=Homo sapiens OX=9606 GN=RBBP4 PE=1 SV=3 5.08 3989.4 - 1.53E+06 - - - 0.0269 - 2.316 0.561 - 377.4 1 1 0 0 12 0 0 0 - - - - - 5.3943 0.9996 221125_WJC_METTL3_EV_vs_WT_F01.22352.22352.2 0.0126 16-Sep K.AFLLESLLK[136.11].N sp|Q96JM3|CHAP1_HUMAN 1 1040.6361 -1 9674 22352 2 1040.637723 521.3253 Chromosome alignment-maintaining phosphoprotein 1 OS=Homo sapiens OX=9606 GN=CHAMP1 PE=1 SV=2 6.05 3989.5 - 1.36E+06 - - - 1.5279 - 1.955 0.396 - 269.6 1 2 0 0.0016 9 0 0 0 0.00E+00 0.00E+00 - - - 3.9048 0.9999 221125_WJC_METTL3_EV_vs_WT_F01.22353.22353.2 0.000419 13/28 R.ATSFLLALEPELEAR.L "sp|P04843|RPN1_HUMAN,tr|F8WF32|F8WF32_HUMAN" 2 1658.8879 -1 9675 22353 2 1658.888877 830.4512 Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit 1 OS=Homo sapiens OX=9606 GN=RPN1 PE=1 SV=1 4.25 3989.6 - 1.21E+06 - - - 0.5666 - 2.588 0.452 - 410.2 1 2 0 0.0009 15 0 0 0 0.00E+00 0.00E+00 - - - 4.717 0.9995 221125_WJC_METTL3_EV_vs_WT_F01.22355.22355.2 0.0741 16-Sep K.AFLLESLLK.N sp|Q96JM3|CHAP1_HUMAN 1 1032.6219 -1 9677 22355 2 1032.623093 517.3182 Chromosome alignment-maintaining phosphoprotein 1 OS=Homo sapiens OX=9606 GN=CHAMP1 PE=1 SV=2 6.05 3989.9 - 920279 - - - 1.1234 - 1.796 0.358 - 280.3 1 2 0 0.0012 9 0 0 0 0.00E+00 0.00E+00 - - - 3.3789 0.9539 221125_WJC_METTL3_EV_vs_WT_F01.22358.22358.2 0.0192 18-Jul E.QEEDISSLIR.S sp|P78527|PRKDC_HUMAN 1 1188.5986 0.5 9680 22358 2 1188.6 595.3066 DNA-dependent protein kinase catalytic subunit OS=Homo sapiens OX=9606 GN=PRKDC PE=1 SV=3 4.14 3990.2 - 689691 - - - 1.1509 - 1.522 0.364 - 142.8 1 1 0 0.0014 10 0 0 0 2.53E+06 5.06E+06 - - - 2.9015 1 221125_WJC_METTL3_EV_vs_WT_F01.22360.22360.3 0.036 14/56 R.AVPLALALISVSNPR[166.11].L "sp|Q13200|PSMD2_HUMAN,tr|H7C1H2|H7C1H2_HUMAN" 2 1529.9169 0.65 9682 22360 3 1529.918354 510.9796 26S proteasome non-ATPase regulatory subunit 2 OS=Homo sapiens OX=9606 GN=PSMD2 PE=1 SV=3 9.79 3990.5 - 570967 - - - 0.9615 - 2.526 0.453 - 239.3 1 2 0 0.0015 15 0 0 0 1.74E+06 2.69E+06 - - - 6.008 1 221125_WJC_METTL3_EV_vs_WT_F01.22361.22361.3 0.0105 14/52 K.FLTLPPVLHLQLMR[166.11].F "sp|Q93009|UBP7_HUMAN,tr|A0A669KBL1|A0A669KBL1_HUMAN,tr|F5H2X1|F5H2X1_HUMAN,tr|H3BND8|H3BND8_HUMAN" 4 1686.9883 0.6 9683 22361 3 1686.990044 563.3367 Ubiquitin carboxyl-terminal hydrolase 7 OS=Homo sapiens OX=9606 GN=USP7 PE=1 SV=2 9.76 3990.6 - 564571 - - - 1.0492 - 2.55 0.464 - 204.1 1 2 0 0.0018 14 0 0 0 9.28E+05 1.55E+06 - - - 6.2003 0.9997 221125_WJC_METTL3_EV_vs_WT_F01.22363.22363.2 0.00352 Sep-36 K.LAAIIPDPVVAPSIVPVLK.D "sp|Q12996|CSTF3_HUMAN,tr|E9PLP8|E9PLP8_HUMAN" 2 1911.1809 -1 9685 22363 2 1911.181856 956.5977 Cleavage stimulation factor subunit 3 OS=Homo sapiens OX=9606 GN=CSTF3 PE=1 SV=1 5.84 3990.9 - 535403 - - - 0.5149 - 2.006 0.411 - 150.5 1 2 0 0.001 19 0 0 0 0.00E+00 0.00E+00 - - - 3.7878 0.976 221125_WJC_METTL3_EV_vs_WT_F01.22364.22364.2 0.00167 14-Jul K.DFGNYLFN.F sp|Q96A49|SYAP1_HUMAN 1 988.429 - 9686 22364 2 988.430146 495.2218 Synapse-associated protein 1 OS=Homo sapiens OX=9606 GN=SYAP1 PE=1 SV=1 3.8 3991 - 510358 - - - 1.1119 - 1.378 0.487 - 171.9 1 1 0 0.0011 8 0 0 0 - - - - - 3.6047 1 221125_WJC_METTL3_EV_vs_WT_F01.22365.22365.2 1.49E-06 14/24 R.DPTYFGPVLNYLR[166.11].H "sp|Q9NXV2|KCTD5_HUMAN,tr|H3BSS5|H3BSS5_HUMAN" 2 1563.7961 4.3 9687 22365 2 1563.802086 782.9053 BTB\POZ domain-containing protein KCTD5 OS=Homo sapiens OX=9606 GN=KCTD5 PE=1 SV=1 5.83 3991.1 - 463548 - - - 3.8285 - 2.658 0.61 - 770 1 2 0 0.006 13 0 0 0 1.02E+07 2.38E+06 - - - 6.0536 0.8858 221125_WJC_METTL3_EV_vs_WT_F01.22367.22367.2 5.72 22-Jun K.TLADVLVQEVIK[136.11].Q "sp|P49441|INPP_HUMAN,tr|C9J2Z6|C9J2Z6_HUMAN,tr|E7ET59|E7ET59_HUMAN,tr|C9J128|C9J128_HUMAN,tr|B8ZZF6|B8ZZF6_HUMAN,tr|C9J173|C9J173_HUMAN,tr|E7ENF2|E7ENF2_HUMAN,tr|E7EUX4|E7EUX4_HUMAN" 8 1334.7901 -1 9688 22367 2 1334.792277 668.4023 Inositol polyphosphate 1-phosphatase OS=Homo sapiens OX=9606 GN=INPP1 PE=1 SV=1 4.37 3991.5 - 255172 - - - 1.6549 - 0.971 0.059 - 63.4 1 2 0 0.0022 12 0 0 0 0.00E+00 0.00E+00 - - - -0.6014 1 221125_WJC_METTL3_EV_vs_WT_F01.22369.22369.2 2.23E-10 14/30 R.FDQLFDDESDPFEVLK[136.11].A sp|Q8NC51|PAIRB_HUMAN 1 1950.8978 -1 9690 22369 2 1950.897386 976.4562 Plasminogen activator inhibitor 1 RNA-binding protein OS=Homo sapiens OX=9606 GN=SERBP1 PE=1 SV=2 3.66 3991.7 - 1.46E+06 - - - -0.2327 - 2.919 0.657 - 527.5 1 2 0 -0.0005 16 0 0 0 0.00E+00 0.00E+00 - - - 6.5272 1 221125_WJC_METTL3_EV_vs_WT_F01.22370.22370.2 1.83E-08 16/30 R.FDQLFDDESDPFEVLK.A sp|Q8NC51|PAIRB_HUMAN 1 1942.8836 -1 9691 22370 2 1942.885941 972.4491 Plasminogen activator inhibitor 1 RNA-binding protein OS=Homo sapiens OX=9606 GN=SERBP1 PE=1 SV=2 3.66 3991.8 - 1.31E+06 - - - 1.1843 - 3.07 0.691 - 715.9 1 2 0 0.0023 16 0 0 0 0.00E+00 0.00E+00 - - - 6.9017 0.9999 221125_WJC_METTL3_EV_vs_WT_F01.22372.22372.2 3.22E-05 20-Oct R.DLEDFFSAVGK[136.11].V "sp|Q86U06|RBM23_HUMAN,tr|G3XAP0|G3XAP0_HUMAN,tr|G3V546|G3V546_HUMAN,tr|G3V2B4|G3V2B4_HUMAN,tr|G3V225|G3V225_HUMAN" 5 1234.5961 -1 9693 22372 2 1234.597097 618.3053 Probable RNA-binding protein 23 OS=Homo sapiens OX=9606 GN=RBM23 PE=1 SV=1 4.03 3992 - 873518 - - - 0.7922 - 2.117 0.538 - 244.3 1 2 0 0.001 11 0 0 0 0.00E+00 0.00E+00 - - - 5.0433 0.9011 221125_WJC_METTL3_EV_vs_WT_F01.22374.22374.2 0.00582 18-Aug K.QDAFANFANF.S sp|Q14677|EPN4_HUMAN 1 1143.4985 - 9695 22374 2 1143.499627 572.7565 Clathrin interactor 1 OS=Homo sapiens OX=9606 GN=CLINT1 PE=1 SV=1 3.8 3992.3 - 768619 - - - 0.9655 - 1.558 0.244 - 110.4 1 1 0 0.0011 10 0 0 0 - - - - - 2.0805 0.9999 221125_WJC_METTL3_EV_vs_WT_F01.22376.22376.2 2.31E-07 26-Nov K.YVVLSYLGLLSQEK.L "sp|Q9BXK5|B2L13_HUMAN,tr|F6VJB4|F6VJB4_HUMAN,tr|A0A0A0MR90|A0A0A0MR90_HUMAN,tr|F2Z2C3|F2Z2C3_HUMAN,tr|E9PDD6|E9PDD6_HUMAN,tr|A0A087WW80|A0A087WW80_HUMAN" 6 1610.892 -1 9697 22376 2 1610.892521 806.4533 Bcl-2-like protein 13 OS=Homo sapiens OX=9606 GN=BCL2L13 PE=1 SV=1 6 3992.5 - 716147 - - - 0.3483 - 2.376 0.548 - 308.3 1 2 0 0.0006 14 0 0 0 0.00E+00 0.00E+00 - - - 5.2601 1 221125_WJC_METTL3_EV_vs_WT_F01.22377.22377.2 6.74E-06 13/22 R.ELEDYIDNLLVR.V "sp|Q6WKZ4|RFIP1_HUMAN,sp|Q7L804|RFIP2_HUMAN,tr|E7EX40|E7EX40_HUMAN" 3 1490.7617 -1 9698 22377 2 1490.767675 746.3881 Rab11 family-interacting protein 1 OS=Homo sapiens OX=9606 GN=RAB11FIP1 PE=1 SV=3 3.92 3992.7 - 576182 - - - 4.0255 - 2.425 0.607 - 661.1 1 2 0 0.006 12 0 0 0 0.00E+00 0.00E+00 - - - 5.8532 0.9998 221125_WJC_METTL3_EV_vs_WT_F01.22378.22378.2 3.06E-05 14/28 R.AVPLALALISVSNPR[166.11].L "sp|Q13200|PSMD2_HUMAN,tr|H7C1H2|H7C1H2_HUMAN" 2 1529.9169 -1 9699 22378 2 1529.919221 765.9657 26S proteasome non-ATPase regulatory subunit 2 OS=Homo sapiens OX=9606 GN=PSMD2 PE=1 SV=3 9.79 3992.8 - 522389 - - - 1.5282 - 2.534 0.509 - 475.5 1 2 0 0.0023 15 0 0 0 0.00E+00 0.00E+00 - - - 5.0857 0.9998 221125_WJC_METTL3_EV_vs_WT_F01.22379.22379.2 0.000241 26-Aug K.YVVLSYLGLLSQEK[136.11].L "sp|Q9BXK5|B2L13_HUMAN,tr|F6VJB4|F6VJB4_HUMAN,tr|A0A0A0MR90|A0A0A0MR90_HUMAN,tr|F2Z2C3|F2Z2C3_HUMAN,tr|E9PDD6|E9PDD6_HUMAN,tr|A0A087WW80|A0A087WW80_HUMAN" 6 1618.9062 -1 9700 22379 2 1618.905919 810.4604 Bcl-2-like protein 13 OS=Homo sapiens OX=9606 GN=BCL2L13 PE=1 SV=1 6 3992.9 - 481889 - - - -0.1489 - 1.947 0.456 - 162.4 1 2 0 -0.0002 14 0 0 0 0.00E+00 0.00E+00 - - - 4.081 0.9999 221125_WJC_METTL3_EV_vs_WT_F01.22382.22382.2 1.76E-06 14/28 R.AVPLALALISVSNPR.L "sp|Q13200|PSMD2_HUMAN,tr|H7C1H2|H7C1H2_HUMAN" 2 1519.9086 -1 9703 22382 2 1519.909348 760.9616 26S proteasome non-ATPase regulatory subunit 2 OS=Homo sapiens OX=9606 GN=PSMD2 PE=1 SV=3 9.79 3993.3 - 392024 - - - 0.4836 - 2.533 0.518 - 673.6 1 2 0 0.0007 15 0 0 0 0.00E+00 0.00E+00 - - - 5.1517 0.9709 221125_WJC_METTL3_EV_vs_WT_F01.22388.22388.2 0.00717 24-Aug K.APDEETLIALLAH.A "sp|Q9Y3E5|PTH2_HUMAN,tr|J3KQ48|J3KQ48_HUMAN" 2 1391.7296 - 9708 22388 2 1391.730151 696.8721 "Peptidyl-tRNA hydrolase 2, mitochondrial OS=Homo sapiens OX=9606 GN=PTRH2 PE=1 SV=1" 4.13 3994 - 162628 - - - 0.3629 - 1.628 0.377 - 171.4 1 1 0 0.0005 13 0 0 0 - - - - - 3.0762 1 221125_WJC_METTL3_EV_vs_WT_F01.22390.22390.2 1.22E-08 16/30 K.AAGVNVEPFWPGLFAK.A sp|P05386|RLA1_HUMAN 1 1701.8879 1.42 9710 22390 2 1701.889366 851.9512 60S acidic ribosomal protein P1 OS=Homo sapiens OX=9606 GN=RPLP1 PE=1 SV=1 6.05 3994.2 - 1.81E+07 - - - 0.8743 - 3.112 0.66 - 604.4 1 2 0 0.0015 16 0 0 0 7.14E+07 5.03E+07 - - - 6.7064 1 221125_WJC_METTL3_EV_vs_WT_F01.22391.22391.2 1.88E-08 15/30 K.AAGVNVEPFWPGLFAK[136.11].A sp|P05386|RLA1_HUMAN 1 1709.9021 1.42 9711 22391 2 1709.901388 855.9583 60S acidic ribosomal protein P1 OS=Homo sapiens OX=9606 GN=RPLP1 PE=1 SV=1 6.05 3994.2 - 1.30E+07 - - - -0.4035 - 2.868 0.622 - 567.7 1 2 0 -0.0007 16 0 0 0 7.14E+07 5.03E+07 - - - 6.2252 1 221125_WJC_METTL3_EV_vs_WT_F01.22392.22392.3 2.40E-05 18/60 K.AAGVNVEPFWPGLFAK.A sp|P05386|RLA1_HUMAN 1 1701.8879 1.59 9712 22392 3 1701.890749 568.3032 60S acidic ribosomal protein P1 OS=Homo sapiens OX=9606 GN=RPLP1 PE=1 SV=1 6.05 3994.3 - 4.58E+06 - - - 1.687 - 3.215 0.534 - 298.5 1 2 0 0.0029 16 0 0 0 1.45E+07 9.12E+06 - - - 7.4893 1 221125_WJC_METTL3_EV_vs_WT_F01.22393.22393.3 3.21E-08 14/60 K.AAGVNVEPFWPGLFAK[136.11].A sp|P05386|RLA1_HUMAN 1 1709.9021 1.59 9713 22393 3 1709.903025 570.9746 60S acidic ribosomal protein P1 OS=Homo sapiens OX=9606 GN=RPLP1 PE=1 SV=1 6.05 3994.3 - 3.20E+06 - - - 0.5538 - 2.723 0.507 - 142.9 1 2 0 0.0009 16 0 0 0 1.45E+07 9.12E+06 - - - 6.7626 1 221125_WJC_METTL3_EV_vs_WT_F01.22394.22394.2 6.81E-10 16/26 K.DMLEAGILDTYLGK.Y "sp|P50990|TCPQ_HUMAN,tr|H7C2U0|H7C2U0_HUMAN" 2 1537.7698 0.36 9714 22394 2 1537.771307 769.8922 T-complex protein 1 subunit theta OS=Homo sapiens OX=9606 GN=CCT8 PE=1 SV=4 4.03 3994.4 - 2.20E+06 - - - 0.9826 - 3.092 0.66 - 704 1 2 0 0.0015 14 0 0 0 1.15E+07 3.23E+07 - - - 6.748 1 221125_WJC_METTL3_EV_vs_WT_F01.22396.22396.3 1.09E-06 14/52 K.DMLEAGILDTYLGK[136.11].Y "sp|P50990|TCPQ_HUMAN,tr|H7C2U0|H7C2U0_HUMAN" 2 1545.784 -1 9716 22396 3 1545.784898 516.2686 T-complex protein 1 subunit theta OS=Homo sapiens OX=9606 GN=CCT8 PE=1 SV=4 4.03 3994.6 - 1.09E+06 - - - 0.5835 - 2.693 0.628 - 387.3 1 2 0 0.0009 14 0 0 0 0.00E+00 0.00E+00 - - - 8.174 0.9909 221125_WJC_METTL3_EV_vs_WT_F01.22397.22397.2 1.69E-06 14/32 K.APPNLPPGVPPLLPNPY.L "sp|Q14157|UBP2L_HUMAN,tr|F8W726|F8W726_HUMAN,tr|H7C2T8|H7C2T8_HUMAN,tr|H0Y5H6|H0Y5H6_HUMAN" 4 1751.961 - 9717 22397 2 1751.96343 876.9878 Ubiquitin-associated protein 2-like OS=Homo sapiens OX=9606 GN=UBAP2L PE=1 SV=2 5.57 3994.7 - 1.08E+06 - - - 1.3625 - 2.313 0.569 - 266.7 1 1 0 0.0024 17 0 0 0 - - - - - 5.3045 1 221125_WJC_METTL3_EV_vs_WT_F01.22402.22402.3 0.0234 28/64 R.LGLAAAAAAAAAELYGR.A sp|Q96T25|ZIC5_HUMAN 1 1558.8467 1.98 9722 22402 3 1558.84778 520.6229 Zinc finger protein ZIC 5 OS=Homo sapiens OX=9606 GN=ZIC5 PE=1 SV=2 6 3995.3 - 734536 - - - 0.6665 - 4.453 0.527 - 1543.9 1 2 0 0.001 17 0 0 0 3.79E+06 1.92E+06 - - - 8.1885 0.9995 221125_WJC_METTL3_EV_vs_WT_F01.22404.22404.2 0.289 18-Nov R.ILVLTELLER.K "sp|Q9NWX5|ASB6_HUMAN,tr|F6TX30|F6TX30_HUMAN" 2 1197.7333 -1 9724 22404 2 1197.733895 599.8739 Ankyrin repeat and SOCS box protein 6 OS=Homo sapiens OX=9606 GN=ASB6 PE=1 SV=1 4.53 3995.5 - 719366 - - - 0.5176 - 2.175 0.267 - 510.4 1 2 0 0.0006 10 0 0 0 0.00E+00 0.00E+00 - - - 3.1818 0.9999 221125_WJC_METTL3_EV_vs_WT_F01.22410.22410.3 0.0027 Sep-52 K.DMLEAGILDTYLGK.Y "sp|P50990|TCPQ_HUMAN,tr|H7C2U0|H7C2U0_HUMAN" 2 1537.7698 -1 9729 22410 3 1537.771787 513.5972 T-complex protein 1 subunit theta OS=Homo sapiens OX=9606 GN=CCT8 PE=1 SV=4 4.03 3996.3 - 1.04E+06 - - - 1.2947 - 2.325 0.408 - 139.6 1 2 0 0.002 14 0 0 0 0.00E+00 0.00E+00 - - - 5.3305 0.9999 221125_WJC_METTL3_EV_vs_WT_F01.22412.22412.3 0.000213 16/56 R.QVLLSAAEAAEVILR[166.11].V sp|P78371|TCPB_HUMAN 1 1591.9173 0.72 9731 22412 3 1591.914483 531.6464 T-complex protein 1 subunit beta OS=Homo sapiens OX=9606 GN=CCT2 PE=1 SV=4 4.53 3996.4 - 9.39E+06 - - - -1.7551 - 2.88 0.441 - 434.4 1 2 0 -0.0028 15 0 0 0 1.45E+07 2.00E+07 - - - 6.2161 0.9999 221125_WJC_METTL3_EV_vs_WT_F01.22413.22413.2 4.66E-07 26-Dec R.APIASIHSFELDLL.- sp|Q13015|AF1Q_HUMAN 1 1524.8188 - 9732 22413 2 1524.817445 763.4167 Protein AF1q OS=Homo sapiens OX=9606 GN=MLLT11 PE=1 SV=1 4.35 3996.4 - 8.31E+06 - - - -0.8854 - 2.234 0.559 - 455.2 1 2 0 -0.0014 14 0 0 0 - - - - - 5.1864 0.9998 221125_WJC_METTL3_EV_vs_WT_F01.22414.22414.2 0.528 20-Sep R.LNIFDMMAVTK.E sp|Q92665|RT31_HUMAN 1 1281.6461 -1 9733 22414 2 1281.644685 641.8303 "28S ribosomal protein S31, mitochondrial OS=Homo sapiens OX=9606 GN=MRPS31 PE=1 SV=3" 5.84 3996.5 - 1.73E+06 - - - -1.1165 - 2.047 0.478 - 214.1 1 2 0 -0.0014 11 0 0 0 0.00E+00 0.00E+00 - - - 4.509 0.9998 221125_WJC_METTL3_EV_vs_WT_F01.22415.22415.2 0.00387 13/24 R.DILVEADSLWVVK.M sp|Q15208|STK38_HUMAN 1 1485.8079 -1 9734 22415 2 1485.807202 743.9112 Serine\threonine-protein kinase 38 OS=Homo sapiens OX=9606 GN=STK38 PE=1 SV=1 4.03 3996.5 - 1.55E+06 - - - -0.4671 - 2.637 0.377 - 496.4 1 2 0 -0.0007 13 0 0 0 0.00E+00 0.00E+00 - - - 4.3139 1 221125_WJC_METTL3_EV_vs_WT_F01.22417.22417.2 4.89E-10 15/24 R.DLYEDELVPLFEK.A "sp|O43390|HNRPR_HUMAN,tr|B4DT28|B4DT28_HUMAN,tr|A0A6Q8PH31|A0A6Q8PH31_HUMAN,tr|A0A6Q8PEX7|A0A6Q8PEX7_HUMAN,tr|A0A6Q8PH35|A0A6Q8PH35_HUMAN" 5 1608.7923 -1 9736 22417 2 1608.788216 805.4034 Heterogeneous nuclear ribonucleoprotein R OS=Homo sapiens OX=9606 GN=HNRNPR PE=1 SV=1 3.83 3996.7 - 1.09E+06 - - - -2.5423 - 2.629 0.657 - 476.1 1 2 0 -0.0041 13 0 0 0 0.00E+00 0.00E+00 - - - 6.3731 0.9998 221125_WJC_METTL3_EV_vs_WT_F01.22418.22418.2 0.021 20-Oct R.LNIFDMMAVTK[136.11].E sp|Q92665|RT31_HUMAN 1 1289.6603 -1 9737 22418 2 1289.659052 645.8374 "28S ribosomal protein S31, mitochondrial OS=Homo sapiens OX=9606 GN=MRPS31 PE=1 SV=3" 5.84 3996.8 - 1.08E+06 - - - -0.9801 - 2.072 0.497 - 312.9 1 2 0 -0.0013 11 0 0 0 0.00E+00 0.00E+00 - - - 4.6822 1 221125_WJC_METTL3_EV_vs_WT_F01.22419.22419.2 2.15E-06 15/28 R.ELIQTSALNFLTPLR[166.11].N "sp|Q9Y371|SHLB1_HUMAN,tr|A0A087WW40|A0A087WW40_HUMAN" 2 1724.97 -1 9738 22419 2 1724.967268 863.4923 Endophilin-B1 OS=Homo sapiens OX=9606 GN=SH3GLB1 PE=1 SV=1 6.1 3996.9 - 1.03E+06 - - - -1.6076 - 2.912 0.592 - 861.9 1 2 0 -0.0028 15 0 0 0 0.00E+00 0.00E+00 - - - 6.0404 0.9999 221125_WJC_METTL3_EV_vs_WT_F01.22420.22420.2 4.80E-05 13/20 R.NVFLLGFIPAK[136.11].A sp|Q92900|RENT1_HUMAN 1 1225.7314 -1 9739 22420 2 1225.730633 613.873 Regulator of nonsense transcripts 1 OS=Homo sapiens OX=9606 GN=UPF1 PE=1 SV=2 8.75 3997 - 960148 - - - -0.651 - 2.159 0.526 - 549.4 1 2 0 -0.0008 11 0 0 0 0.00E+00 0.00E+00 - - - 5.0079 0.9997 221125_WJC_METTL3_EV_vs_WT_F01.22421.22421.2 0.000174 18-Sep R.DGFIDLMELK[136.11].L "sp|Q96C19|EFHD2_HUMAN,sp|Q9BUP0|EFHD1_HUMAN,tr|A0A087X1Z2|A0A087X1Z2_HUMAN,tr|H0Y4Y4|H0Y4Y4_HUMAN" 4 1187.5988 0.74 9740 22421 2 1187.5973 594.8067 EF-hand domain-containing protein D2 OS=Homo sapiens OX=9606 GN=EFHD2 PE=1 SV=1 4.03 3997.1 - 911308 - - - -1.2302 - 1.65 0.461 - 151.4 1 2 0 -0.0015 10 0 0 0 1.87E+06 2.51E+06 - - - 3.8433 0.9999 221125_WJC_METTL3_EV_vs_WT_F01.22422.22422.2 0.000983 18/32 R.LGLAAAAAAAAAELYGR.A sp|Q96T25|ZIC5_HUMAN 1 1558.8467 -1 9741 22422 2 1558.847665 780.4306 Zinc finger protein ZIC 5 OS=Homo sapiens OX=9606 GN=ZIC5 PE=1 SV=2 6 3997.3 - 796105 - - - 0.5927 - 3.137 0.462 - 741.2 1 2 0 0.0009 17 0 0 0 0.00E+00 0.00E+00 - - - 5.2638 1 221125_WJC_METTL3_EV_vs_WT_F01.22424.22424.2 4.52E-09 16/24 R.DLYEDELVPLFEK[136.11].A "sp|O43390|HNRPR_HUMAN,tr|B4DT28|B4DT28_HUMAN,tr|A0A6Q8PH31|A0A6Q8PH31_HUMAN,tr|A0A6Q8PEX7|A0A6Q8PEX7_HUMAN,tr|A0A6Q8PH35|A0A6Q8PH35_HUMAN" 5 1616.8065 2.1 9743 22424 2 1616.804927 809.4105 Heterogeneous nuclear ribonucleoprotein R OS=Homo sapiens OX=9606 GN=HNRNPR PE=1 SV=1 3.83 3997.5 - 725224 - - - -0.9766 - 2.796 0.663 - 715.5 1 2 0 -0.0016 13 0 0 0 1.31E+07 6.24E+06 - - - 6.5763 1 221125_WJC_METTL3_EV_vs_WT_F01.22427.22427.2 3.67E-05 30-Dec R.VLFDPFELDTSVTPGR.V "sp|Q15269|PWP2_HUMAN,tr|A0A0B4J2E5|A0A0B4J2E5_HUMAN" 2 1791.9043 -1 9746 22427 2 1791.908811 896.9594 Periodic tryptophan protein 2 homolog OS=Homo sapiens OX=9606 GN=PWP2 PE=2 SV=2 4.03 3997.9 - 665387 - - - 2.5085 - 2.841 0.563 - 341.6 1 2 0 0.0045 16 0 0 0 0.00E+00 0.00E+00 - - - 5.765 0.876 221125_WJC_METTL3_EV_vs_WT_F01.22428.22428.3 0.502 Jun-60 K.IFEIFGPVAHPFYVLR.F sp|Q96HR8|NAF1_HUMAN 1 1904.0349 -1 9747 22428 3 1904.03485 635.6856 H\ACA ribonucleoprotein complex non-core subunit NAF1 OS=Homo sapiens OX=9606 GN=NAF1 PE=1 SV=2 6.75 3998 - 663298 - - - -0.0137 - 1.244 0.109 - 33.3 1 2 0 0 16 0 0 0 0.00E+00 0.00E+00 - - - 0.3154 0.9998 221125_WJC_METTL3_EV_vs_WT_F01.22430.22430.2 0.000163 14/28 R.QVLLSAAEAAEVILR[166.11].V sp|P78371|TCPB_HUMAN 1 1591.9173 0.55 9748 22430 2 1591.914138 796.9659 T-complex protein 1 subunit beta OS=Homo sapiens OX=9606 GN=CCT2 PE=1 SV=4 4.53 3998.2 - 4.68E+06 - - - -1.9718 - 3.339 0.492 - 696.8 1 2 0 -0.0031 15 0 0 0 1.40E+07 2.52E+07 - - - 5.6381 1 221125_WJC_METTL3_EV_vs_WT_F01.22431.22431.2 2.40E-09 30-Nov R.VLFDPFELDTSVTPGR[166.11].V "sp|Q15269|PWP2_HUMAN,tr|A0A0B4J2E5|A0A0B4J2E5_HUMAN" 2 1801.9126 -1 9749 22431 2 1801.910978 901.9636 Periodic tryptophan protein 2 homolog OS=Homo sapiens OX=9606 GN=PWP2 PE=2 SV=2 4.03 3998.4 - 204310 - - - -0.8924 - 2.528 0.608 - 276.4 1 2 0 -0.0016 16 0 0 0 0.00E+00 0.00E+00 - - - 5.8113 0.9999 221125_WJC_METTL3_EV_vs_WT_F01.22437.22437.2 5.22E-06 22-Nov R.LLTSFLPAQLLR.L "sp|P08195|4F2_HUMAN,tr|A0A7P0TAN7|A0A7P0TAN7_HUMAN,tr|J3KPF3|J3KPF3_HUMAN,tr|F5H056|F5H056_HUMAN,tr|F5GZI0|F5GZI0_HUMAN,tr|A0A7P0T8U7|A0A7P0T8U7_HUMAN,tr|A0A7P0T9F7|A0A7P0T9F7_HUMAN,tr|A0A7P0TBF8|A0A7P0TBF8_HUMAN,tr|A0A7P0T8F1|A0A7P0T8F1_HUMAN,tr|H0YFX4|H0YFX4_HUMAN,tr|A0A7P0Z4A0|A0A7P0Z4A0_HUMAN,tr|F5GZS6|F5GZS6_HUMAN,tr|A0A7P0Z4P5|A0A7P0Z4P5_HUMAN,tr|A0A7P0TAS6|A0A7P0TAS6_HUMAN" 14 1370.8286 -1 9755 22437 2 1370.828261 686.4216 4F2 cell-surface antigen heavy chain OS=Homo sapiens OX=9606 GN=SLC3A2 PE=1 SV=3 9.75 3998.7 - 1.98E+06 - - - -0.2269 - 2.148 0.537 - 298.7 1 2 0 -0.0003 12 0 0 0 0.00E+00 0.00E+00 - - - 5.0188 0.9936 221125_WJC_METTL3_EV_vs_WT_F01.22441.22441.3 8.68E-06 Dec-64 K.APPNLPPGVPPLLPNPY.L "sp|Q14157|UBP2L_HUMAN,tr|F8W726|F8W726_HUMAN,tr|H7C2T8|H7C2T8_HUMAN,tr|H0Y5H6|H0Y5H6_HUMAN" 4 1751.961 - 9759 22441 3 1751.960156 584.9943 Ubiquitin-associated protein 2-like OS=Homo sapiens OX=9606 GN=UBAP2L PE=1 SV=2 5.57 3999.1 - 1.02E+06 - - - -0.5063 - 2.185 0.463 - 107.5 1 1 0 -0.0009 17 0 0 0 - - - - - 5.6763 0.8863 221125_WJC_METTL3_EV_vs_WT_F01.22442.22442.2 1.97 20-Aug R.INSIEIAPC[160.03]LL.- sp|Q7Z2W9|RM21_HUMAN 1 1241.669 - 9760 22442 2 1241.667346 621.8418 "39S ribosomal protein L21, mitochondrial OS=Homo sapiens OX=9606 GN=MRPL21 PE=1 SV=2" 4 3999.2 - 994922 - - - -1.2999 - 1.01 0.02 - 122.1 1 2 0 -0.0016 11 0 0 0 - - - - - -0.7849 0.9999 221125_WJC_METTL3_EV_vs_WT_F01.22443.22443.3 0.00757 Oct-48 R.DLYEDELVPLFEK[136.11].A "sp|O43390|HNRPR_HUMAN,tr|B4DT28|B4DT28_HUMAN,tr|A0A6Q8PH31|A0A6Q8PH31_HUMAN,tr|A0A6Q8PEX7|A0A6Q8PEX7_HUMAN,tr|A0A6Q8PH35|A0A6Q8PH35_HUMAN" 5 1616.8065 -1 9761 22443 3 1616.807075 539.9428 Heterogeneous nuclear ribonucleoprotein R OS=Homo sapiens OX=9606 GN=HNRNPR PE=1 SV=1 3.83 3999.3 - 993507 - - - 0.3519 - 1.973 0.42 - 119.2 1 2 0 0.0006 13 0 0 0 0.00E+00 0.00E+00 - - - 5.0649 1 221125_WJC_METTL3_EV_vs_WT_F01.22446.22446.2 1.37E-07 18/32 R.LVSDIIDPVALEIPLSK.N "sp|Q5UIP0|RIF1_HUMAN,tr|H7C2B5|H7C2B5_HUMAN" 2 1821.0499 -1 9764 22446 2 1821.049475 911.5322 Telomere-associated protein RIF1 OS=Homo sapiens OX=9606 GN=RIF1 PE=1 SV=2 4.03 3999.7 - 715841 - - - -0.2427 - 3.158 0.542 - 802.5 1 2 0 -0.0004 17 0 0 0 0.00E+00 0.00E+00 - - - 5.8713 0.9874 221125_WJC_METTL3_EV_vs_WT_F01.22453.22453.2 6.40E-07 26-Dec R.DYLHLPPEIVPATL.H "sp|Q9NQ39|RS10L_HUMAN,sp|P46783|RS10_HUMAN,tr|A0A2R8Y6L3|A0A2R8Y6L3_HUMAN,tr|F6U211|F6U211_HUMAN,tr|A0A1W2PQS6|A0A1W2PQS6_HUMAN,tr|A0A2R8YFH6|A0A2R8YFH6_HUMAN,tr|A0A2R8Y7H1|A0A2R8Y7H1_HUMAN,tr|S4R435|S4R435_HUMAN" 8 1576.8501 - 9770 22453 2 1576.852868 789.4323 Putative 40S ribosomal protein S10-like OS=Homo sapiens OX=9606 GN=RPS10P5 PE=5 SV=1 4.35 4000.6 - 3.40E+06 - - - 1.7586 - 2.192 0.554 - 414 1 1 0 0.0028 14 0 0 0 - - - - - 5.1014 0.9989 221125_WJC_METTL3_EV_vs_WT_F01.22459.22459.3 0.00245 Dec-64 R.LVSDIIDPVALEIPLSK.N "sp|Q5UIP0|RIF1_HUMAN,tr|H7C2B5|H7C2B5_HUMAN" 2 1821.0499 -1 9776 22459 3 1821.05392 608.0239 Telomere-associated protein RIF1 OS=Homo sapiens OX=9606 GN=RIF1 PE=1 SV=2 4.03 4001.2 - 637221 - - - 2.1982 - 1.724 0.353 - 113.4 1 2 0 0.004 17 0 0 0 0.00E+00 0.00E+00 - - - 3.8504 0.9999 221125_WJC_METTL3_EV_vs_WT_F01.22461.22461.2 4.19E-05 Oct-32 R.LVSDIIDPVALEIPLSK[136.11].N "sp|Q5UIP0|RIF1_HUMAN,tr|H7C2B5|H7C2B5_HUMAN" 2 1829.0641 -1 9778 22461 2 1829.065152 915.5393 Telomere-associated protein RIF1 OS=Homo sapiens OX=9606 GN=RIF1 PE=1 SV=2 4.03 4001.5 - 588996 - - - 0.5659 - 2.292 0.557 - 205.8 1 2 0 0.001 17 0 0 0 0.00E+00 0.00E+00 - - - 5.1939 0.9903 221125_WJC_METTL3_EV_vs_WT_F01.22464.22464.2 0.00542 28-Jul R.NLVPLLLAPENLVEK.E "sp|Q8NHH9|ATLA2_HUMAN,tr|B5MCN0|B5MCN0_HUMAN,tr|C9JQQ5|C9JQQ5_HUMAN" 3 1660.9764 -1 9781 22464 2 1660.97863 831.4955 Atlastin-2 OS=Homo sapiens OX=9606 GN=ATL2 PE=1 SV=2 4.53 4001.9 - 455069 - - - 1.3679 - 1.502 0.143 - 99.1 2 2 0 0.0023 15 0 0 0 0.00E+00 0.00E+00 - - - 0.9621 0.9998 221125_WJC_METTL3_EV_vs_WT_F01.22476.22476.2 0.000317 24-Dec R.GDLTPLDSLIDFK.R "sp|Q96QA5|GSDMA_HUMAN,tr|J3KRG2|J3KRG2_HUMAN" 2 1432.745 -1 9792 22476 2 1432.746625 717.3798 Gasdermin-A OS=Homo sapiens OX=9606 GN=GSDMA PE=1 SV=4 3.93 4003.2 - 1.14E+06 - - - 1.1607 - 2.699 0.444 - 590.7 1 2 0 0.0017 13 0 0 0 0.00E+00 0.00E+00 - - - 4.8681 0.997 221125_WJC_METTL3_EV_vs_WT_F01.22479.22479.2 0.0229 18-Nov K.NLLQLLPIPK.S sp|Q5T3J3|LRIF1_HUMAN 1 1147.7329 1.75 9795 22479 2 1147.734262 574.8737 Ligand-dependent nuclear receptor-interacting factor 1 OS=Homo sapiens OX=9606 GN=LRIF1 PE=1 SV=1 8.75 4003.5 - 916123 - - - 1.2032 - 2.427 0.051 - 475.9 2 2 0 0.0014 10 0 0 0 3.77E+06 2.16E+06 - - - 1.7577 0.9999 221125_WJC_METTL3_EV_vs_WT_F01.22481.22481.2 3.66E-06 26-Nov K.VWINTSDIILVGLR[166.11].D "sp|O14602|IF1AY_HUMAN,sp|P47813|IF1AX_HUMAN,tr|X6RAC9|X6RAC9_HUMAN" 3 1607.9274 -1 9797 22481 2 1607.927956 804.971 "Eukaryotic translation initiation factor 1A, Y-chromosomal OS=Homo sapiens OX=9606 GN=EIF1AY PE=1 SV=4" 5.81 4003.7 - 767107 - - - 0.3159 - 2.73 0.524 - 394.2 1 2 0 0.0005 14 0 0 0 0.00E+00 0.00E+00 - - - 5.4313 1 221125_WJC_METTL3_EV_vs_WT_F01.22483.22483.2 5.64E-13 14/34 K.VVLDVGSGTGILC[160.03]MFAAK.A "sp|Q99873|ANM1_HUMAN,tr|E9PQ98|E9PQ98_HUMAN,tr|E9PKG1|E9PKG1_HUMAN,tr|E9PNR9|E9PNR9_HUMAN,tr|H0YDE4|H0YDE4_HUMAN,tr|E9PMW9|E9PMW9_HUMAN,tr|E9PIX6|E9PIX6_HUMAN" 7 1836.9478 3.18 9799 22483 2 1836.949676 919.4812 Protein arginine N-methyltransferase 1 OS=Homo sapiens OX=9606 GN=PRMT1 PE=1 SV=3 5.8 4004 - 633613 - - - 1.0332 - 3.026 0.706 - 452.5 1 2 0 0.0019 18 0 0 0 1.74E+06 5.47E+05 - - - 6.9771 0.9999 221125_WJC_METTL3_EV_vs_WT_F01.22484.22484.3 0.000694 Oct-52 K.VEWSAFLEAADNLR.L sp|Q9UI30|TR112_HUMAN 1 1619.7944 -1 9800 22484 3 1619.797448 540.9387 Multifunctional methyltransferase subunit TRM112-like protein OS=Homo sapiens OX=9606 GN=TRMT112 PE=1 SV=1 4.14 4004.1 - 627217 - - - 1.8996 - 2.256 0.449 - 146.6 1 2 0 0.0031 14 0 0 0 0.00E+00 0.00E+00 - - - 5.7072 0.9177 221125_WJC_METTL3_EV_vs_WT_F01.22485.22485.2 0.0556 Aug-42 K.IGGPLGTGAFGAPGFNTTTATL.G "sp|P52948|NUP98_HUMAN,tr|A0A3B3ITD8|A0A3B3ITD8_HUMAN,tr|H0YEN4|H0YEN4_HUMAN" 3 2020.0266 - 9801 22485 2 2020.024991 1011.0206 Nuclear pore complex protein Nup98-Nup96 OS=Homo sapiens OX=9606 GN=NUP98 PE=1 SV=4 5.52 4004.3 - 626281 - - - -0.7747 - 1.485 0.284 - 100.3 1 1 0 -0.0016 22 0 0 0 - - - - - 2.1103 1 221125_WJC_METTL3_EV_vs_WT_F01.22486.22486.2 1.68E-07 15/26 R.LLVPTQFVGAIIGK[136.11].E "sp|O00425|IF2B3_HUMAN,sp|Q9Y6M1|IF2B2_HUMAN,tr|F8W930|F8W930_HUMAN" 3 1462.9003 -1 9802 22486 2 1462.901419 732.4574 Insulin-like growth factor 2 mRNA-binding protein 3 OS=Homo sapiens OX=9606 GN=IGF2BP3 PE=1 SV=2 8.75 4004.4 - 622642 - - - 0.7738 - 2.752 0.579 - 521.9 1 2 0 0.0011 14 0 0 0 0.00E+00 0.00E+00 - - - 5.8575 1 221125_WJC_METTL3_EV_vs_WT_F01.22487.22487.2 3.17E-06 26-Dec K.VEWSAFLEAADNLR[166.11].L sp|Q9UI30|TR112_HUMAN 1 1629.8026 -1 9803 22487 2 1629.800977 815.9086 Multifunctional methyltransferase subunit TRM112-like protein OS=Homo sapiens OX=9606 GN=TRMT112 PE=1 SV=1 4.14 4004.5 - 575306 - - - -1.021 - 2.633 0.588 - 499 1 2 0 -0.0017 14 0 0 0 0.00E+00 0.00E+00 - - - 5.8129 0.9091 221125_WJC_METTL3_EV_vs_WT_F01.22488.22488.3 0.265 Jul-52 K.VWINTSDIILVGLR[166.11].D "sp|O14602|IF1AY_HUMAN,sp|P47813|IF1AX_HUMAN,tr|X6RAC9|X6RAC9_HUMAN" 3 1607.9274 -1 9804 22488 3 1607.929197 536.9831 "Eukaryotic translation initiation factor 1A, Y-chromosomal OS=Homo sapiens OX=9606 GN=EIF1AY PE=1 SV=4" 5.81 4004.6 - 559776 - - - 1.0877 - 1.309 0.119 - 47.8 1 2 0 0.0017 14 0 0 0 0.00E+00 0.00E+00 - - - 0.5818 0.9998 221125_WJC_METTL3_EV_vs_WT_F01.22490.22490.2 0.00894 18-Dec K.NLLQLLPIPK[136.11].S sp|Q5T3J3|LRIF1_HUMAN 1 1155.7471 -1 9806 22490 2 1155.748322 578.8808 Ligand-dependent nuclear receptor-interacting factor 1 OS=Homo sapiens OX=9606 GN=LRIF1 PE=1 SV=1 8.75 4004.9 - 534016 - - - 1.0738 - 2.575 0.45 - 483.5 1 2 0 0.0012 10 0 0 0 0.00E+00 0.00E+00 - - - 5.0045 0.7768 221125_WJC_METTL3_EV_vs_WT_F01.22493.22493.3 0.0478 Aug-52 R.DYLHLPPEIVPATL.H "sp|Q9NQ39|RS10L_HUMAN,sp|P46783|RS10_HUMAN,tr|A0A2R8Y6L3|A0A2R8Y6L3_HUMAN,tr|F6U211|F6U211_HUMAN,tr|A0A1W2PQS6|A0A1W2PQS6_HUMAN,tr|A0A2R8YFH6|A0A2R8YFH6_HUMAN,tr|A0A2R8Y7H1|A0A2R8Y7H1_HUMAN,tr|S4R435|S4R435_HUMAN" 8 1576.8501 - 9808 22493 3 1576.85252 526.624 Putative 40S ribosomal protein S10-like OS=Homo sapiens OX=9606 GN=RPS10P5 PE=5 SV=1 4.35 4005.3 - 240361 - - - 1.5379 - 1.569 0.282 - 75.8 1 1 0 0.0024 14 0 0 0 - - - - - 2.8804 0.9798 221125_WJC_METTL3_EV_vs_WT_F01.22494.22494.2 0.00128 28-Sep R.IPLNPYLNLHSLLPA.S "tr|E9PAU2|E9PAU2_HUMAN,tr|A0A087WZ13|A0A087WZ13_HUMAN" 2 1673.9505 - 9809 22494 2 1673.951937 837.9825 Ribonucleoprotein PTB-binding 1 OS=Homo sapiens OX=9606 GN=RAVER1 PE=1 SV=1 6.74 4005.4 - 682953 - - - 0.8716 - 1.99 0.399 - 167.6 1 1 0 0.0015 15 0 0 0 - - - - - 3.6794 0.9999 221125_WJC_METTL3_EV_vs_WT_F01.22495.22495.2 0.000523 18-Nov K.DSTLIMQLLR[166.11].D "sp|P31946|1433B_HUMAN,sp|P62258|1433E_HUMAN,sp|P27348|1433T_HUMAN,sp|P63104|1433Z_HUMAN,sp|Q04917|1433F_HUMAN,sp|P31947|1433S_HUMAN,sp|P61981|1433G_HUMAN,tr|K7EM20|K7EM20_HUMAN,tr|H0YB80|H0YB80_HUMAN,tr|E7EX29|E7EX29_HUMAN,tr|B7Z2E6|B7Z2E6_HUMAN,tr|B0AZS6|B0AZS6_HUMAN" 12 1198.6619 -1 9810 22495 2 1198.662262 600.3382 14-3-3 protein beta\alpha OS=Homo sapiens OX=9606 GN=YWHAB PE=1 SV=3 5.84 4005.4 - 4.99E+06 - - - 0.2903 - 2.41 0.532 - 571.5 1 2 0 0.0003 10 0 0 0 0.00E+00 0.00E+00 - - - 5.4255 0.9998 221125_WJC_METTL3_EV_vs_WT_F01.22496.22496.2 0.00122 18-Oct K.DSTLIMQLLR.D "sp|P31946|1433B_HUMAN,sp|P62258|1433E_HUMAN,sp|P27348|1433T_HUMAN,sp|P63104|1433Z_HUMAN,sp|Q04917|1433F_HUMAN,sp|P31947|1433S_HUMAN,sp|P61981|1433G_HUMAN,tr|K7EM20|K7EM20_HUMAN,tr|H0YB80|H0YB80_HUMAN,tr|E7EX29|E7EX29_HUMAN,tr|B7Z2E6|B7Z2E6_HUMAN,tr|B0AZS6|B0AZS6_HUMAN" 12 1188.6536 -1 9811 22496 2 1188.654235 595.3341 14-3-3 protein beta\alpha OS=Homo sapiens OX=9606 GN=YWHAB PE=1 SV=3 5.84 4005.5 - 4.97E+06 - - - 0.4972 - 2.089 0.442 - 471.8 1 2 0 0.0006 10 0 0 0 0.00E+00 0.00E+00 - - - 4.3617 1 221125_WJC_METTL3_EV_vs_WT_F01.22498.22498.2 1.49E-09 22-Dec R.TFC[160.03]QLILDPIFK[136.11].V sp|P13639|EF2_HUMAN 1 1501.8094 -1 9813 22498 2 1501.809558 751.912 Elongation factor 2 OS=Homo sapiens OX=9606 GN=EEF2 PE=1 SV=4 5.5 4005.6 - 1.97E+06 - - - 0.0899 - 2.411 0.669 - 480 1 2 0 0.0001 12 0 0 0 0.00E+00 0.00E+00 - - - 6.2977 0.9999 221125_WJC_METTL3_EV_vs_WT_F01.22501.22501.2 3.13E-07 28-Oct K.EMVPEFVVPDLTGFK.L sp|Q8IXM3|RM41_HUMAN 1 1706.8589 -1 9816 22501 2 1706.859298 854.4367 "39S ribosomal protein L41, mitochondrial OS=Homo sapiens OX=9606 GN=MRPL41 PE=1 SV=1" 4.14 4005.9 - 923994 - - - 0.2068 - 2.047 0.645 - 247.6 1 2 0 0.0004 15 0 0 0 0.00E+00 0.00E+00 - - - 5.5661 1 221125_WJC_METTL3_EV_vs_WT_F01.22502.22502.2 6.14E-09 Dec-32 K.LLQTDDEEEAGLLELLK.S sp|P55060|XPO2_HUMAN 1 1927.999 -1 9817 22502 2 1927.999419 965.0068 Exportin-2 OS=Homo sapiens OX=9606 GN=CSE1L PE=1 SV=3 3.77 4006 - 749384 - - - 0.2152 - 3.08 0.659 - 430.2 1 2 0 0.0004 17 0 0 0 0.00E+00 0.00E+00 - - - 6.6739 0.9999 221125_WJC_METTL3_EV_vs_WT_F01.22503.22503.2 5.12E-08 13/18 R.DPLLLAIIPK[136.11].Y "sp|Q9HAV4|XPO5_HUMAN,tr|H0Y9I3|H0Y9I3_HUMAN" 2 1099.7096 -1 9818 22503 2 1099.709868 550.8621 Exportin-5 OS=Homo sapiens OX=9606 GN=XPO5 PE=1 SV=1 5.84 4006.2 - 733855 - - - 0.2146 - 2.548 0.473 - 577 1 2 0 0.0002 10 0 0 0 0.00E+00 0.00E+00 - - - 5.1452 1 221125_WJC_METTL3_EV_vs_WT_F01.22505.22505.2 7.63E-11 13/32 K.LLQTDDEEEAGLLELLK[136.11].S sp|P55060|XPO2_HUMAN 1 1936.0132 -1 9820 22505 2 1936.011723 969.0139 Exportin-2 OS=Homo sapiens OX=9606 GN=CSE1L PE=1 SV=3 3.77 4006.4 - 609768 - - - -0.765 - 3.071 0.628 - 442.2 1 2 0 -0.0015 17 0 0 0 0.00E+00 0.00E+00 - - - 6.4374 1 221125_WJC_METTL3_EV_vs_WT_F01.22507.22507.2 5.56E-08 13/28 R.ELTMASLPFTFDVER[166.11].S sp|Q9H0D6|XRN2_HUMAN 1 1764.8632 -1 9822 22507 2 1764.862124 883.4389 5'-3' exoribonuclease 2 OS=Homo sapiens OX=9606 GN=XRN2 PE=1 SV=1 4.14 4006.7 - 547332 - - - -0.6057 - 2.861 0.566 - 370 1 2 0 -0.0011 15 0 0 0 0.00E+00 0.00E+00 - - - 5.8055 0.9999 221125_WJC_METTL3_EV_vs_WT_F01.22508.22508.2 3.43E-06 24-Nov R.LGLDILEVVPISK.S "sp|Q8IX18|DHX40_HUMAN,tr|F5H625|F5H625_HUMAN" 2 1394.8385 -1 9823 22508 2 1394.83877 698.4265 Probable ATP-dependent RNA helicase DHX40 OS=Homo sapiens OX=9606 GN=DHX40 PE=1 SV=2 4.37 4006.8 - 539127 - - - 0.2165 - 2.549 0.563 - 385.9 1 2 0 0.0003 13 0 0 0 0.00E+00 0.00E+00 - - - 5.6007 0.9995 221125_WJC_METTL3_EV_vs_WT_F01.22517.22517.2 2.60E-05 26-Sep K.ITPENLPQILLQLK.R "sp|P43243|MATR3_HUMAN,tr|A8MXP9|A8MXP9_HUMAN,tr|D6R991|D6R991_HUMAN,tr|A0A0R4J2E8|A0A0R4J2E8_HUMAN,tr|D6REM6|D6REM6_HUMAN" 5 1618.9658 -1 9831 22517 2 1618.969886 810.4902 Matrin-3 OS=Homo sapiens OX=9606 GN=MATR3 PE=1 SV=2 6 4007.7 - 1.88E+07 - - - 2.5275 - 1.821 0.528 - 161 1 2 0 0.0041 14 0 0 0 0.00E+00 0.00E+00 - - - 4.4437 0.9961 221125_WJC_METTL3_EV_vs_WT_F01.22518.22518.2 0.0175 26-Jul K.ITPENLPQILLQLK[136.11].R "sp|P43243|MATR3_HUMAN,tr|A8MXP9|A8MXP9_HUMAN,tr|D6R991|D6R991_HUMAN,tr|A0A0R4J2E8|A0A0R4J2E8_HUMAN,tr|D6REM6|D6REM6_HUMAN" 5 1626.98 -1 9832 22518 2 1626.98395 814.4973 Matrin-3 OS=Homo sapiens OX=9606 GN=MATR3 PE=1 SV=2 6 4007.7 - 1.23E+07 - - - 2.4315 - 1.348 0.321 - 113 1 2 0 0.004 14 0 0 0 0.00E+00 0.00E+00 - - - 2.16 0.9998 221125_WJC_METTL3_EV_vs_WT_F01.23606.23606.2 0.00353 16-Oct R.YLDVSILGK[136.11].F sp|Q86U44|MTA70_HUMAN 1 1014.5841 0.02 9895 23606 2 1014.585196 508.2993 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 5.83 4218.8 - 82608.9 - - - 1.0822 - 1.912 0.494 - 259.3 1 2 0 0.0011 9 0 0 0 2.27E+05 1.40E+07 - - - 4.5645 0.9991 221125_WJC_METTL3_EV_vs_WT_F01.23609.23609.2 0.00552 16-Aug R.IAIYELLFK.E "sp|P46783|RS10_HUMAN,tr|A0A2R8Y6L3|A0A2R8Y6L3_HUMAN,tr|F6U211|F6U211_HUMAN,tr|A0A1W2PQS6|A0A1W2PQS6_HUMAN,tr|A0A2R8YFH6|A0A2R8YFH6_HUMAN,tr|A0A2R8Y7H1|A0A2R8Y7H1_HUMAN" 6 1108.6532 1.14 9896 23609 2 1108.654875 555.3339 40S ribosomal protein S10 OS=Homo sapiens OX=9606 GN=RPS10 PE=1 SV=1 6 4219.3 - 162589 - - - 1.4811 - 1.668 0.336 - 138.6 1 2 0 0.0016 9 0 0 0 7.82E+05 6.86E+05 - - - 3.0023 0.9955 221125_WJC_METTL3_EV_vs_WT_F01.23610.23610.2 0.619 16-Aug R.IAIYELLFK[136.11].E "sp|P46783|RS10_HUMAN,tr|A0A2R8Y6L3|A0A2R8Y6L3_HUMAN,tr|F6U211|F6U211_HUMAN,tr|A0A1W2PQS6|A0A1W2PQS6_HUMAN,tr|A0A2R8YFH6|A0A2R8YFH6_HUMAN,tr|A0A2R8Y7H1|A0A2R8Y7H1_HUMAN" 6 1116.6674 1.14 9897 23610 2 1116.668767 559.341 40S ribosomal protein S10 OS=Homo sapiens OX=9606 GN=RPS10 PE=1 SV=1 6 4219.4 - 147972 - - - 1.1946 - 1.654 0.13 - 139.7 1 2 0 0.0013 9 0 0 0 7.82E+05 6.86E+05 - - - 1.4565 0.9244 221125_WJC_METTL3_EV_vs_WT_F01.23614.23614.2 0.305 26-Mar K.ITPENLPQILLQLK.R "sp|P43243|MATR3_HUMAN,tr|A8MXP9|A8MXP9_HUMAN,tr|D6R991|D6R991_HUMAN,tr|A0A0R4J2E8|A0A0R4J2E8_HUMAN,tr|D6REM6|D6REM6_HUMAN" 5 1618.9658 1.73 9900 23614 2 1618.968998 810.4902 Matrin-3 OS=Homo sapiens OX=9606 GN=MATR3 PE=1 SV=2 6 4219.9 - 33869.1 - - - 1.979 - 0.9 0.168 - 21.2 3 2 0 0.0032 14 0 0 0 1.22E+05 7.02E+04 - - - -0.1967 0.7999 221125_WJC_METTL3_EV_vs_WT_F01.23764.23764.2 2.3 16-Apr R.YLDVSILGK[136.11].F sp|Q86U44|MTA70_HUMAN 1 1014.5841 0.01 9909 23764 2 1014.582749 508.2993 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 5.83 4249.1 - 31167.5 - - - -1.3296 - 0.874 0.022 - 36 1 2 0 -0.0013 9 0 0 0 2.55E+05 2.16E+07 - - - -1.1866 0.9993 221125_WJC_METTL3_EV_vs_WT_F01.24424.24424.2 0.00373 16-Sep R.YLDVSILGK[136.11].F sp|Q86U44|MTA70_HUMAN 1 1014.5841 0.001 9916 24424 2 1014.581705 508.2993 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 5.83 4383 - 283081 - - - -2.3586 - 1.783 0.418 - 200 1 2 0 -0.0024 9 0 0 0 0.00E+00 2.05E+06 - - - 3.8006 0.9432 221125_WJC_METTL3_EV_vs_WT_F02.02272.02272.2 4.36 12-Feb K.VNTSPR[166.11]R.K "sp|Q8WZ74|CTTB2_HUMAN,tr|H0Y448|H0Y448_HUMAN" 2 838.4649 - 9924 2272 2 838.465262 420.2397 Cortactin-binding protein 2 OS=Homo sapiens OX=9606 GN=CTTNBP2 PE=1 SV=1 12 1175.1 - 416449 - - - 0.4687 - 0.557 0.317 - 23.4 1 2 0 0.0004 7 0 0 0 - - - - - -0.472 0.9972 221125_WJC_METTL3_EV_vs_WT_F02.02882.02882.2 0.00578 22-Jul R.FSSSGGGGGGGR.F sp|P35527|K1C9_HUMAN 1 981.4264 112.99 9947 2882 2 981.423155 491.7205 "Keratin, type I cytoskeletal 9 OS=Homo sapiens OX=9606 GN=KRT9 PE=1 SV=3" 9.75 1287.3 - 83987.7 - - - -3.3278 - 1.457 0.409 - 125.8 1 2 0 -0.0033 12 0 0 0 5.23E+06 4.63E+04 - - - 3.0512 0.8889 221125_WJC_METTL3_EV_vs_WT_F02.03092.03092.2 0.319 12-Apr K.LTPQGQR[166.11].D "sp|P39019|RS19_HUMAN,tr|A0A075B6E2|A0A075B6E2_HUMAN" 2 808.4431 0.39 9955 3092 2 808.440416 405.2288 40S ribosomal protein S19 OS=Homo sapiens OX=9606 GN=RPS19 PE=1 SV=2 9.75 1325.1 - 92597.6 - - - -3.2841 - 0.901 0.187 - 69.6 1 2 0 -0.0027 7 0 0 0 1.88E+06 4.77E+06 - - - 0.091 0.9823 221125_WJC_METTL3_EV_vs_WT_F02.03119.03119.2 0.0277 18-Jun K.TAEAGGVTGK[136.11].G "sp|P09874|PARP1_HUMAN,tr|A0A7I2V5E9|A0A7I2V5E9_HUMAN,tr|A0A7I2V625|A0A7I2V625_HUMAN,tr|A0A7I2V3E1|A0A7I2V3E1_HUMAN" 4 897.4647 0.93 9959 3119 2 897.46131 449.7396 Poly [ADP-ribose] polymerase 1 OS=Homo sapiens OX=9606 GN=PARP1 PE=1 SV=4 5.66 1329.7 - 67903.2 - - - -3.7896 - 1.156 0.305 - 118.5 1 2 0 -0.0034 10 0 0 0 1.27E+06 1.37E+06 - - - 1.6973 0.9947 221125_WJC_METTL3_EV_vs_WT_F02.03141.03141.2 0.000193 26-Jul R.GSGGGSSGGSIGGR.G sp|P04264|K2C1_HUMAN 1 1091.4956 999 9960 3141 2 1091.490258 546.7551 "Keratin, type II cytoskeletal 1 OS=Homo sapiens OX=9606 GN=KRT1 PE=1 SV=6" 9.75 1333.6 - 77347.4 - - - -4.8603 - 1.589 0.454 - 149.7 1 2 0 -0.0053 14 0 0 0 2.24E+06 0.00E+00 - - - 3.5547 0.9333 221125_WJC_METTL3_EV_vs_WT_F02.03163.03163.2 0.108 12-Jun R.MVQEAEK[136.11].Y "sp|P0DMV8|HS71A_HUMAN,sp|P11142|HSP7C_HUMAN,sp|P0DMV9|HS71B_HUMAN,tr|E9PNE6|E9PNE6_HUMAN,tr|A8K7Q2|A8K7Q2_HUMAN,tr|E9PKE3|E9PKE3_HUMAN,tr|E9PM13|E9PM13_HUMAN,tr|E9PS65|E9PS65_HUMAN,tr|V9GZ37|V9GZ37_HUMAN,tr|A0A0G2JIW1|A0A0G2JIW1_HUMAN" 10 841.4095 0.13 9962 3163 2 841.404977 421.712 Heat shock 70 kDa protein 1A OS=Homo sapiens OX=9606 GN=HSPA1A PE=1 SV=1 4.53 1337.3 - 190914 - - - -5.3803 - 1.181 0.265 - 121.2 1 2 0 -0.0045 7 0 0 0 2.33E+06 1.75E+07 - - - 1.524 0.9034 221125_WJC_METTL3_EV_vs_WT_F02.03209.03209.2 0.165 12-May K.HPELADK[136.11].N "sp|Q9NQ39|RS10L_HUMAN,sp|P46783|RS10_HUMAN,tr|A0A2R8Y6L3|A0A2R8Y6L3_HUMAN,tr|F6U211|F6U211_HUMAN,tr|A0A1W2PQS6|A0A1W2PQS6_HUMAN,tr|A0A2R8YFH6|A0A2R8YFH6_HUMAN,tr|A0A2R8Y7H1|A0A2R8Y7H1_HUMAN,tr|S4R435|S4R435_HUMAN" 8 816.4221 1.35 9964 3209 2 816.418144 409.2183 Putative 40S ribosomal protein S10-like OS=Homo sapiens OX=9606 GN=RPS10P5 PE=5 SV=1 5.32 1345.2 - 210061 - - - -4.8676 - 1.125 0.21 - 71.7 1 2 0 -0.004 7 0 0 0 9.28E+06 6.85E+06 - - - 0.964 0.9453 221125_WJC_METTL3_EV_vs_WT_F02.03212.03212.2 0.319 12-Jul K.HPELADK.N "sp|Q9NQ39|RS10L_HUMAN,sp|P46783|RS10_HUMAN,tr|A0A2R8Y6L3|A0A2R8Y6L3_HUMAN,tr|F6U211|F6U211_HUMAN,tr|A0A1W2PQS6|A0A1W2PQS6_HUMAN,tr|A0A2R8YFH6|A0A2R8YFH6_HUMAN,tr|A0A2R8Y7H1|A0A2R8Y7H1_HUMAN,tr|S4R435|S4R435_HUMAN" 8 808.4079 0.39 9965 3212 2 808.402735 405.2112 Putative 40S ribosomal protein S10-like OS=Homo sapiens OX=9606 GN=RPS10P5 PE=5 SV=1 5.32 1345.6 - 189278 - - - -6.4114 - 1.53 0.255 - 138.6 1 2 0 -0.0052 7 0 0 0 1.05E+07 2.70E+07 - - - 2.2703 0.9657 221125_WJC_METTL3_EV_vs_WT_F02.03952.03952.3 0.0231 Nov-36 R.LRSEIDNVKK.Q sp|P04264|K2C1_HUMAN 1 1200.6826 999 10000 3952 3 1200.681671 401.2348 "Keratin, type II cytoskeletal 1 OS=Homo sapiens OX=9606 GN=KRT1 PE=1 SV=6" 8.59 1476.9 - 323706 - - - -0.8037 - 1.633 0.179 - 122.8 1 2 1 -0.001 10 0 0 0 7.64E+06 0.00E+00 - - - 1.9676 0.9925 221125_WJC_METTL3_EV_vs_WT_F02.03957.03957.2 0.393 12-Jul R.FTDEESR.V "sp|Q9NYF8|BCLF1_HUMAN,tr|H0YF00|H0YF00_HUMAN,tr|E9PKI6|E9PKI6_HUMAN,tr|A0A1W2PQ43|A0A1W2PQ43_HUMAN,tr|E9PK91|E9PK91_HUMAN,tr|E9PK09|E9PK09_HUMAN,tr|E9PQN2|E9PQN2_HUMAN" 7 882.3719 2.39 10001 3957 2 882.371447 442.1932 Bcl-2-associated transcription factor 1 OS=Homo sapiens OX=9606 GN=BCLAF1 PE=1 SV=2 4.14 1477.7 - 214921 - - - -0.5429 - 1.153 0.182 - 174 1 2 0 -0.0005 7 0 0 0 9.80E+06 4.10E+06 - - - 0.8362 0.8173 221125_WJC_METTL3_EV_vs_WT_F02.03963.03963.2 0.158 12-May R.FTDEESR[166.11].V "sp|Q9NYF8|BCLF1_HUMAN,tr|H0YF00|H0YF00_HUMAN,tr|E9PKI6|E9PKI6_HUMAN,tr|A0A1W2PQ43|A0A1W2PQ43_HUMAN,tr|E9PK91|E9PK91_HUMAN,tr|E9PK09|E9PK09_HUMAN,tr|E9PQN2|E9PQN2_HUMAN" 7 892.3802 2.39 10002 3963 2 892.377196 447.1974 Bcl-2-associated transcription factor 1 OS=Homo sapiens OX=9606 GN=BCLAF1 PE=1 SV=2 4.14 1478.7 - 144225 - - - -3.3618 - 1.16 0.034 - 82.9 1 2 0 -0.003 7 0 0 0 9.80E+06 4.10E+06 - - - -0.2385 0.9941 221125_WJC_METTL3_EV_vs_WT_F02.04019.04019.2 0.142 14-Jul R.NTEEEGLK.Y "sp|Q9NYF8|BCLF1_HUMAN,tr|E9PKI6|E9PKI6_HUMAN,tr|A0A1W2PQ43|A0A1W2PQ43_HUMAN,tr|E9PK91|E9PK91_HUMAN,tr|E9PK09|E9PK09_HUMAN,tr|E9PQN2|E9PQN2_HUMAN" 6 918.4294 1.59 10004 4019 2 918.427762 460.222 Bcl-2-associated transcription factor 1 OS=Homo sapiens OX=9606 GN=BCLAF1 PE=1 SV=2 4.25 1488.7 - 1.14E+06 - - - -1.8281 - 1.359 0.22 - 135.1 2 2 0 -0.0017 8 0 0 0 3.30E+07 2.08E+07 - - - 1.4561 0.9997 221125_WJC_METTL3_EV_vs_WT_F02.04029.04029.2 3.57E-05 16-Jul K.TQELETTQK.H "sp|P52732|KIF11_HUMAN,tr|A0A7I2YQY4|A0A7I2YQY4_HUMAN,tr|A0A7I2V3A9|A0A7I2V3A9_HUMAN,tr|A0A7I2V3V3|A0A7I2V3V3_HUMAN" 4 1076.535 2.79 10005 4029 2 1076.533296 539.2748 Kinesin-like protein KIF11 OS=Homo sapiens OX=9606 GN=KIF11 PE=1 SV=2 4.53 1490.4 - 100045 - - - -1.5541 - 1.634 0.509 - 125.7 1 2 0 -0.0017 9 0 0 0 3.91E+06 1.40E+06 - - - 4.2205 0.978 221125_WJC_METTL3_EV_vs_WT_F02.04052.04052.2 1.11 12-Jul R.EAQVNVR.M "sp|Q9Y2W1|TR150_HUMAN,tr|A0A3B3ITZ9|A0A3B3ITZ9_HUMAN" 2 814.4297 3.12 10008 4052 2 814.42789 408.2221 Thyroid hormone receptor-associated protein 3 OS=Homo sapiens OX=9606 GN=THRAP3 PE=1 SV=2 6.1 1494.2 - 474996 - - - -2.2421 - 1.322 0.107 - 234.1 1 2 0 -0.0018 7 0 0 0 1.83E+07 5.88E+06 - - - 0.7152 0.8575 221125_WJC_METTL3_EV_vs_WT_F02.04191.04191.2 0.687 16-Jun R.SSPATADKR.Q "sp|Q8TF72|SHRM3_HUMAN,tr|A0A2R8Y5P9|A0A2R8Y5P9_HUMAN" 2 931.4723 127.13 10012 4191 2 931.468532 466.7434 Protein Shroom3 OS=Homo sapiens OX=9606 GN=SHROOM3 PE=1 SV=2 8.46 1518.5 - 236546 - - - -4.0549 - 1.041 0.151 - 124.8 1 2 0 -0.0038 9 0 0 0 8.76E+06 6.89E+04 - - - 0.2713 0.7833 221125_WJC_METTL3_EV_vs_WT_F02.04195.04195.2 0.363 12-May R.NTTIPTK[136.11].K "sp|P38646|GRP75_HUMAN,sp|P54652|HSP72_HUMAN,sp|P11142|HSP7C_HUMAN,tr|E9PNE6|E9PNE6_HUMAN,tr|A8K7Q2|A8K7Q2_HUMAN,tr|E9PKE3|E9PKE3_HUMAN,tr|A0A7I2V2S7|A0A7I2V2S7_HUMAN,tr|A0A7I2V2G2|A0A7I2V2G2_HUMAN,tr|E9PS65|E9PS65_HUMAN,tr|A0A7I2YQB2|A0A7I2YQB2_HUMAN,tr|D6RCD7|D6RCD7_HUMAN" 11 781.4425 0.25 10013 4195 2 781.439002 391.7285 "Stress-70 protein, mitochondrial OS=Homo sapiens OX=9606 GN=HSPA9 PE=1 SV=2" 8.75 1519 - 1.75E+06 - - - -4.5007 - 1.273 0.047 - 134.1 1 2 0 -0.0035 7 0 0 0 1.83E+07 7.32E+07 - - - 0.1519 0.8886 221125_WJC_METTL3_EV_vs_WT_F02.04201.04201.2 1.06 12-Jul R.NTTIPTK.K "sp|P38646|GRP75_HUMAN,sp|P54652|HSP72_HUMAN,sp|P11142|HSP7C_HUMAN,tr|E9PNE6|E9PNE6_HUMAN,tr|A8K7Q2|A8K7Q2_HUMAN,tr|E9PKE3|E9PKE3_HUMAN,tr|A0A7I2V2S7|A0A7I2V2S7_HUMAN,tr|A0A7I2V2G2|A0A7I2V2G2_HUMAN,tr|E9PS65|E9PS65_HUMAN,tr|A0A7I2YQB2|A0A7I2YQB2_HUMAN,tr|D6RCD7|D6RCD7_HUMAN" 11 773.4283 0.24 10015 4201 2 773.425297 387.7214 "Stress-70 protein, mitochondrial OS=Homo sapiens OX=9606 GN=HSPA9 PE=1 SV=2" 8.75 1519.8 - 439880 - - - -3.9073 - 1.251 0.086 - 195.2 1 2 0 -0.003 7 0 0 0 1.78E+07 7.32E+07 - - - 0.3848 0.9988 221125_WJC_METTL3_EV_vs_WT_F02.04237.04237.2 0.00291 14-Sep K.QASEGPLK.G "sp|P04406|G3P_HUMAN,tr|E7EUT5|E7EUT5_HUMAN" 2 828.4341 0.6 10021 4237 2 828.432046 415.2243 Glyceraldehyde-3-phosphate dehydrogenase OS=Homo sapiens OX=9606 GN=GAPDH PE=1 SV=3 6 1525.5 - 697733 - - - -2.518 - 1.731 0.351 - 369.2 1 2 0 -0.0021 8 0 0 0 2.32E+07 3.86E+07 - - - 3.2877 0.9974 221125_WJC_METTL3_EV_vs_WT_F02.04240.04240.3 0.000785 Jul-36 K.NHEEEMKDLR.N "sp|P13645|K1C10_HUMAN,tr|A0A1B0GVI3|A0A1B0GVI3_HUMAN" 2 1299.5877 0.88 10022 4240 3 1299.584674 434.2032 "Keratin, type I cytoskeletal 10 OS=Homo sapiens OX=9606 GN=KRT10 PE=1 SV=6" 4.83 1525.9 - 375857 - - - -2.3661 - 1.402 0.438 - 49.4 1 2 1 -0.0031 10 0 0 0 7.14E+06 8.15E+06 - - - 4.4092 0.9745 221125_WJC_METTL3_EV_vs_WT_F02.04528.04528.2 0.141 16-Jul K.TIAPQNAPR.D "sp|Q9NYF8|BCLF1_HUMAN,tr|H0YF00|H0YF00_HUMAN,tr|E9PKI6|E9PKI6_HUMAN,tr|A0A1W2PQ43|A0A1W2PQ43_HUMAN,tr|E9PK91|E9PK91_HUMAN,tr|E9PJA7|E9PJA7_HUMAN,tr|E9PK09|E9PK09_HUMAN,tr|E9PQN2|E9PQN2_HUMAN" 8 966.5247 1.5 10047 4528 2 966.524013 484.2696 Bcl-2-associated transcription factor 1 OS=Homo sapiens OX=9606 GN=BCLAF1 PE=1 SV=2 9.41 1573.5 - 476425 - - - -0.6891 - 1.147 0.082 - 151.2 1 2 0 -0.0007 9 0 0 0 7.17E+07 4.80E+07 - - - 0.0432 0.9805 221125_WJC_METTL3_EV_vs_WT_F02.04539.04539.2 2.35 16-Jul K.TIAPQNAPR[166.11].D "sp|Q9NYF8|BCLF1_HUMAN,tr|H0YF00|H0YF00_HUMAN,tr|E9PKI6|E9PKI6_HUMAN,tr|A0A1W2PQ43|A0A1W2PQ43_HUMAN,tr|E9PK91|E9PK91_HUMAN,tr|E9PJA7|E9PJA7_HUMAN,tr|E9PK09|E9PK09_HUMAN,tr|E9PQN2|E9PQN2_HUMAN" 8 976.5329 1.46 10048 4539 2 976.531586 489.2738 Bcl-2-associated transcription factor 1 OS=Homo sapiens OX=9606 GN=BCLAF1 PE=1 SV=2 9.41 1575.5 - 338464 - - - -1.3958 - 1.088 0.172 - 108.6 2 2 0 -0.0014 9 0 0 0 6.53E+07 4.47E+07 - - - 0.4205 0.947 221125_WJC_METTL3_EV_vs_WT_F02.04695.04695.2 12.7 12-May R.EIQTAVR.L "sp|P33778|H2B1B_HUMAN,sp|Q96A08|H2B1A_HUMAN,sp|Q5QNW6|H2B2F_HUMAN,sp|P58876|H2B1D_HUMAN,sp|Q99880|H2B1L_HUMAN,sp|P62807|H2B1C_HUMAN,sp|Q99877|H2B1N_HUMAN,sp|P57053|H2BFS_HUMAN,sp|P23527|H2B1O_HUMAN,sp|O60814|H2B1K_HUMAN,sp|Q93079|H2B1H_HUMAN,sp|Q99879|H2B1M_HUMAN,sp|Q16778|H2B2E_HUMAN,sp|P06899|H2B1J_HUMAN,tr|U3KQK0|U3KQK0_HUMAN" 15 815.4501 1.56 10055 4695 2 815.448671 408.7323 Histone H2B type 1-B OS=Homo sapiens OX=9606 GN=H2BC3 PE=1 SV=2 6.1 1602.9 - 193663 - - - -1.7733 - 1.159 0.054 - 133.3 1 2 0 -0.0014 7 0 0 0 8.72E+06 5.61E+06 - - - -0.0931 0.9998 221125_WJC_METTL3_EV_vs_WT_F02.04759.04759.2 1.01E-05 24-Sep R.FSSSSGYGGGSSR.V sp|P35527|K1C9_HUMAN 1 1234.5214 4.2 10061 4759 2 1234.519945 618.268 "Keratin, type I cytoskeletal 9 OS=Homo sapiens OX=9606 GN=KRT9 PE=1 SV=3" 8.75 1613.6 - 195738 - - - -1.2142 - 1.948 0.571 - 252.6 1 2 0 -0.0015 13 0 0 0 1.20E+07 2.85E+06 - - - 4.9693 0.9841 221125_WJC_METTL3_EV_vs_WT_F02.04797.04797.3 0.0784 Jul-52 K.K[136.11]GPGEVAGTVTGQK[136.11].R "sp|Q86U44|MTA70_HUMAN,tr|F5H6D8|F5H6D8_HUMAN,tr|H0YFV6|H0YFV6_HUMAN,tr|B4DTN4|B4DTN4_HUMAN" 4 1343.738 0 10066 4797 3 1343.735238 448.9199 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 8.59 1619.7 - 80550 - - - -2.0398 - 1.381 0.224 - 42.8 1 2 0 -0.0027 14 0 0 0 2.54E+05 2.55E+08 - - - 1.8945 0.9975 221125_WJC_METTL3_EV_vs_WT_F02.04817.04817.3 0.00733 Sep-36 K.NKYEDEINKR.T "sp|P48668|K2C6C_HUMAN,sp|P05787|K2C8_HUMAN,sp|P04264|K2C1_HUMAN,sp|P04259|K2C6B_HUMAN,sp|P13647|K2C5_HUMAN,sp|P02538|K2C6A_HUMAN,tr|F8VUG2|F8VUG2_HUMAN,tr|F8W0C6|F8W0C6_HUMAN,tr|F8VP67|F8VP67_HUMAN,tr|F8W1U3|F8W1U3_HUMAN" 10 1307.647 1251.33 10067 4817 3 1307.641583 436.8896 "Keratin, type II cytoskeletal 6C OS=Homo sapiens OX=9606 GN=KRT6C PE=1 SV=3" 6.18 1623.2 - 227522 - - - -4.1265 - 1.981 0.457 - 72 1 2 1 -0.0054 10 0 0 0 1.20E+07 9.57E+03 - - - 5.63 0.9987 221125_WJC_METTL3_EV_vs_WT_F02.04856.04856.2 0.00506 26-Jun K.K[136.11]GPGEVAGTVTGQK[136.11].R "sp|Q86U44|MTA70_HUMAN,tr|F5H6D8|F5H6D8_HUMAN,tr|H0YFV6|H0YFV6_HUMAN,tr|B4DTN4|B4DTN4_HUMAN" 4 1343.738 0.001 10069 4856 2 1343.735557 672.8763 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 8.59 1630 - 63662.9 - - - -1.8024 - 1.466 0.362 - 89.3 1 2 0 -0.0024 14 0 0 0 0.00E+00 4.60E+07 - - - 2.6739 1 221125_WJC_METTL3_EV_vs_WT_F02.04965.04965.3 7.02E-09 18/52 K.K[136.11]GPGEVAGTVTGQK[136.11].R "sp|Q86U44|MTA70_HUMAN,tr|F5H6D8|F5H6D8_HUMAN,tr|H0YFV6|H0YFV6_HUMAN,tr|B4DTN4|B4DTN4_HUMAN" 4 1343.738 0 10074 4965 3 1343.739237 448.9199 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 8.59 1650.1 - 2.04E+06 - - - 0.9362 - 3.237 0.566 - 573.3 1 2 0 0.0013 14 0 0 0 2.54E+05 2.55E+08 - - - 7.9717 0.9053 221125_WJC_METTL3_EV_vs_WT_F02.04985.04985.2 35.1 12-Aug R.FLEQQNK.L "sp|P08670|VIME_HUMAN,sp|Q9NSB2|KRT84_HUMAN,sp|P14136|GFAP_HUMAN,sp|Q14533|KRT81_HUMAN,sp|P48668|K2C6C_HUMAN,sp|P05787|K2C8_HUMAN,sp|Q01546|K22O_HUMAN,sp|P19013|K2C4_HUMAN,sp|Q8N1N4|K2C78_HUMAN,sp|P12035|K2C3_HUMAN,sp|P78386|KRT85_HUMAN,sp|P04259|K2C6B_HUMAN,sp|P13647|K2C5_HUMAN,sp|O43790|KRT86_HUMAN,sp|P78385|KRT83_HUMAN,sp|P08729|K2C7_HUMAN,sp|O95678|K2C75_HUMAN,sp|Q5XKE5|K2C79_HUMAN,sp|P02538|K2C6A_HUMAN,tr|A0A1W2PR46|A0A1W2PR46_HUMAN,tr|F8VUG2|F8VUG2_HUMAN,tr|A0A087X106|A0A087X106_HUMAN,tr|A0A1X7SBR3|A0A1X7SBR3_HUMAN,tr|B4DIR1|B4DIR1_HUMAN,tr|K7EJU1|K7EJU1_HUMAN,tr|F8W0C6|F8W0C6_HUMAN,tr|A0A1X7SCE1|A0A1X7SCE1_HUMAN,tr|Q8IWY7|Q8IWY7_HUMAN,tr|U3KPR1|U3KPR1_HUMAN,tr|F8W1U3|F8W1U3_HUMAN,tr|K7EKH9|K7EKH9_HUMAN,tr|B0YJC4|B0YJC4_HUMAN,tr|K7ELP4|K7ELP4_HUMAN,tr|A0A1B0GTT5|A0A1B0GTT5_HUMAN" 34 905.4607 5.92 10075 4985 2 905.4611 453.7376 Vimentin OS=Homo sapiens OX=9606 GN=VIM PE=1 SV=4 6 1653.9 - 1.18E+06 - - - 0.4627 - 0.954 0.04 - 195.9 1 2 0 0.0004 7 0 0 0 7.16E+07 1.21E+07 - - - -0.8129 0.9739 221125_WJC_METTL3_EV_vs_WT_F02.05158.05158.2 2.14 12-Jul K.LLTTGRE.- "sp|Q9NP79|VTA1_HUMAN,tr|Q5TGM0|Q5TGM0_HUMAN,tr|A0A087WY55|A0A087WY55_HUMAN" 3 788.4392 1.75 10088 5158 2 788.438485 395.2269 Vacuolar protein sorting-associated protein VTA1 homolog OS=Homo sapiens OX=9606 GN=VTA1 PE=1 SV=1 6.22 1684.3 - 1.97E+06 - - - -0.9297 - 1.21 0.059 - 117.5 1 2 0 -0.0007 7 0 0 0 5.00E+08 2.85E+08 - - - 0.0805 0.9656 221125_WJC_METTL3_EV_vs_WT_F02.05159.05159.2 6.53 12-Jun K.ILTTEGR[166.11].N sp|Q08211|DHX9_HUMAN 1 798.4475 1.76 10089 5159 2 798.446567 400.231 ATP-dependent RNA helicase A OS=Homo sapiens OX=9606 GN=DHX9 PE=1 SV=4 6 1684.4 - 1.77E+06 - - - -1.1535 - 1.247 0.03 - 110.6 1 2 0 -0.0009 7 0 0 0 5.00E+08 2.85E+08 - - - -0.0383 0.9999 221125_WJC_METTL3_EV_vs_WT_F02.05236.05236.2 0.000238 22-Aug K.VGGTSDVEVNEK.K "sp|P10809|CH60_HUMAN,tr|A0A7I2V2X6|A0A7I2V2X6_HUMAN,tr|A0A7I2YQK6|A0A7I2YQK6_HUMAN,tr|A0A7I2V599|A0A7I2V599_HUMAN" 4 1232.5885 1.6 10100 5236 2 1232.587899 617.3015 "60 kDa heat shock protein, mitochondrial OS=Homo sapiens OX=9606 GN=HSPD1 PE=1 SV=2" 4.14 1697.4 - 192101 - - - -0.456 - 2.105 0.505 - 141.1 1 2 0 -0.0006 12 0 0 0 2.66E+07 1.66E+07 - - - 4.7292 0.9999 221125_WJC_METTL3_EV_vs_WT_F02.05246.05246.2 4.86E-06 22-Oct K.VGGTSDVEVNEK[136.11].K "sp|P10809|CH60_HUMAN,tr|A0A7I2V2X6|A0A7I2V2X6_HUMAN,tr|A0A7I2YQK6|A0A7I2YQK6_HUMAN,tr|A0A7I2V599|A0A7I2V599_HUMAN" 4 1240.6027 1.58 10102 5246 2 1240.602229 621.3086 "60 kDa heat shock protein, mitochondrial OS=Homo sapiens OX=9606 GN=HSPD1 PE=1 SV=2" 4.14 1699 - 267701 - - - -0.3482 - 2.246 0.577 - 283.8 1 2 0 -0.0004 12 0 0 0 2.60E+07 1.65E+07 - - - 5.4316 0.9964 221125_WJC_METTL3_EV_vs_WT_F02.05314.05314.3 0.00472 Nov-44 K.SKAEAESLYQSK.Y sp|P04264|K2C1_HUMAN 1 1339.662 964.44 10113 5314 3 1339.659016 447.5613 "Keratin, type II cytoskeletal 1 OS=Homo sapiens OX=9606 GN=KRT1 PE=1 SV=6" 5.86 1709.9 - 401717 - - - -2.1976 - 1.881 0.336 - 92.7 1 2 1 -0.0029 12 0 0 0 1.45E+07 1.50E+04 - - - 4.0365 0.8367 221125_WJC_METTL3_EV_vs_WT_F02.05346.05346.2 0.0242 14-Jul A.MMGAVAEK[136.11].K "sp|Q86U44|MTA70_HUMAN,tr|A0A0G2JH39|A0A0G2JH39_HUMAN,tr|F5H6D8|F5H6D8_HUMAN,tr|H0YFV6|H0YFV6_HUMAN,tr|B4DTN4|B4DTN4_HUMAN" 5 843.4074 0.03 10117 5346 2 843.405887 422.711 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 5.75 1715.1 - 543558 - - - -1.788 - 1.252 0.296 - 116.1 1 1 0 -0.0015 8 0 0 0 1.62E+06 4.93E+07 - - - 1.9046 0.8976 221125_WJC_METTL3_EV_vs_WT_F02.05587.05587.2 38.3 12-Jul R.TVYGAVR.A "sp|O43251|RFOX2_HUMAN,tr|B0QYV1|B0QYV1_HUMAN,tr|B0QYY4|B0QYY4_HUMAN,tr|A0A0G2JRD1|A0A0G2JRD1_HUMAN,tr|A0A0G2JRA5|A0A0G2JRA5_HUMAN,tr|S4R3K7|S4R3K7_HUMAN" 6 764.4181 1.12 10141 5587 2 764.416949 383.2163 RNA binding protein fox-1 homolog 2 OS=Homo sapiens OX=9606 GN=RBFOX2 PE=1 SV=3 8.41 1754.6 - 898952 - - - -1.49 - 1.02 0.034 - 189.2 1 2 0 -0.0011 7 0 0 0 4.06E+07 3.61E+07 - - - -0.6455 0.8853 221125_WJC_METTL3_EV_vs_WT_F02.05588.05588.2 1.72 12-Jun R.VIPVTSR.N sp|P19387|RPB3_HUMAN 1 770.465 1.34 10142 5588 2 770.462657 386.2398 DNA-directed RNA polymerase II subunit RPB3 OS=Homo sapiens OX=9606 GN=POLR2C PE=1 SV=2 9.72 1754.7 - 833112 - - - -3.0903 - 1.108 0.083 - 185.2 1 2 0 -0.0024 7 0 0 0 1.05E+08 7.87E+07 - - - -0.0218 0.9924 221125_WJC_METTL3_EV_vs_WT_F02.05593.05593.2 8.52 12-Jul M.VLESVAR[166.11].L "sp|Q8N5K1|CISD2_HUMAN,tr|I3L1N9|I3L1N9_HUMAN,tr|A0A2R8Y540|A0A2R8Y540_HUMAN" 3 782.4526 1.01 10143 5593 2 782.451844 392.2336 CDGSH iron-sulfur domain-containing protein 2 OS=Homo sapiens OX=9606 GN=CISD2 PE=1 SV=1 5.97 1755.6 - 1.06E+06 - - - -0.9317 - 1.304 0.139 - 191.8 1 2 0 -0.0007 7 0 0 0 1.09E+08 1.08E+08 - - - 0.9085 0.9821 221125_WJC_METTL3_EV_vs_WT_F02.05595.05595.2 0.728 12-Jun K.FVPAEAR.T "sp|Q9H089|LSG1_HUMAN,tr|F8WFC6|F8WFC6_HUMAN" 2 788.4181 0.56 10144 5595 2 788.417226 395.2163 Large subunit GTPase 1 homolog OS=Homo sapiens OX=9606 GN=LSG1 PE=1 SV=2 6 1755.8 - 288669 - - - -1.0933 - 1.168 0.114 - 158.8 1 2 0 -0.0009 7 0 0 0 1.00E+08 1.79E+08 - - - 0.3748 0.9935 221125_WJC_METTL3_EV_vs_WT_F02.05596.05596.2 1.13 16-Jul K.SAVEDEGLK[136.11].G "sp|P0DMV8|HS71A_HUMAN,sp|P0DMV9|HS71B_HUMAN,tr|V9GZ37|V9GZ37_HUMAN,tr|A0A0G2JIW1|A0A0G2JIW1_HUMAN" 4 954.4749 0.11 10145 5596 2 954.4755 478.2447 Heat shock 70 kDa protein 1A OS=Homo sapiens OX=9606 GN=HSPA1A PE=1 SV=1 4.14 1755.9 - 238040 - - - 0.5857 - 1.3 0.162 - 181.8 1 2 0 0.0006 9 0 0 0 3.18E+06 2.79E+07 - - - 0.9964 0.9519 221125_WJC_METTL3_EV_vs_WT_F02.05617.05617.2 1.92 12-Jun K.FVPAEAR[166.11].T "sp|Q9H089|LSG1_HUMAN,tr|F8WFC6|F8WFC6_HUMAN" 2 798.4264 1.14 10147 5617 2 798.426139 400.2205 Large subunit GTPase 1 homolog OS=Homo sapiens OX=9606 GN=LSG1 PE=1 SV=2 6 1759.5 - 1.16E+06 - - - -0.2743 - 1.016 0.067 - 189.7 1 2 0 -0.0002 7 0 0 0 1.07E+08 9.33E+07 - - - -0.4139 0.9359 221125_WJC_METTL3_EV_vs_WT_F02.05622.05622.2 0.0314 14-Jul R.LLTAEADK.T sp|O43660|PLRG1_HUMAN 1 859.4651 1.04 10148 5622 2 859.460005 430.7398 Pleiotropic regulator 1 OS=Homo sapiens OX=9606 GN=PLRG1 PE=1 SV=1 4.37 1760.3 - 219540 - - - -5.9258 - 1.427 0.236 - 125 1 2 0 -0.0051 8 0 0 0 2.97E+07 2.86E+07 - - - 1.8549 0.9504 221125_WJC_METTL3_EV_vs_WT_F02.05626.05626.2 5.8 18-Jul K.GSAITGPVAK[136.11].E "sp|P62829|RL23_HUMAN,tr|J3KTJ3|J3KTJ3_HUMAN" 2 907.5218 1.05 10149 5626 2 907.521831 454.7682 60S ribosomal protein L23 OS=Homo sapiens OX=9606 GN=RPL23 PE=1 SV=1 8.75 1760.9 - 334420 - - - -0.0011 - 1.161 0.057 - 109.3 5 2 0 0 10 0 0 0 1.95E+07 1.86E+07 - - - -0.4335 0.981 221125_WJC_METTL3_EV_vs_WT_F02.05644.05644.2 1.06 12-Jun R.LGTVYEK[136.11].F "sp|O95757|HS74L_HUMAN,tr|E9PDE8|E9PDE8_HUMAN" 2 816.4473 0.15 10150 5644 2 816.447989 409.2309 Heat shock 70 kDa protein 4L OS=Homo sapiens OX=9606 GN=HSPA4L PE=1 SV=3 6 1764.2 - 980321 - - - 0.8806 - 1.329 0.072 - 89.4 2 2 0 0.0007 7 0 0 0 2.06E+07 1.34E+08 - - - 0.3393 0.9967 221125_WJC_METTL3_EV_vs_WT_F02.05657.05657.2 0.00835 14-Aug R.LLTAEADK[136.11].T sp|O43660|PLRG1_HUMAN 1 867.4793 1.04 10155 5657 2 867.477526 434.7469 Pleiotropic regulator 1 OS=Homo sapiens OX=9606 GN=PLRG1 PE=1 SV=1 4.37 1766 - 606760 - - - -2.0427 - 1.847 0.154 - 172.3 1 2 0 -0.0018 8 0 0 0 2.97E+07 2.86E+07 - - - 2.0284 0.9989 221125_WJC_METTL3_EV_vs_WT_F02.05697.05697.2 0.156 14-Jul R.STLEPVEK[136.11].A "sp|P48741|HSP77_HUMAN,sp|P0DMV8|HS71A_HUMAN,sp|P0DMV9|HS71B_HUMAN,sp|P17066|HSP76_HUMAN,tr|V9GZ37|V9GZ37_HUMAN,tr|A0A0G2JIW1|A0A0G2JIW1_HUMAN" 6 909.4899 0.13 10160 5697 2 909.489737 455.7522 Putative heat shock 70 kDa protein 7 OS=Homo sapiens OX=9606 GN=HSPA7 PE=5 SV=2 4.53 1772.9 - 309416 - - - -0.1385 - 1.65 0.229 - 267.2 1 2 0 -0.0001 8 0 0 0 6.92E+06 5.40E+07 - - - 2.2427 0.9979 221125_WJC_METTL3_EV_vs_WT_F02.05777.05777.2 0.0228 12-Jun K.LVVADTR[166.11].G "sp|P22314|UBA1_HUMAN,tr|Q5JRS0|Q5JRS0_HUMAN,tr|Q5JRR9|Q5JRR9_HUMAN" 3 782.4526 0.57 10174 5777 2 782.452268 392.2336 Ubiquitin-like modifier-activating enzyme 1 OS=Homo sapiens OX=9606 GN=UBA1 PE=1 SV=3 5.84 1785.9 - 900422 - - - -0.3898 - 1.12 0.321 - 174.4 1 2 0 -0.0003 7 0 0 0 8.02E+07 1.41E+08 - - - 1.7709 0.9942 221125_WJC_METTL3_EV_vs_WT_F02.05803.05803.2 0.113 14-Jul K.VLEAGMGK[136.11].V "sp|Q9UBN7|HDAC6_HUMAN,tr|A0A2R8YDE6|A0A2R8YDE6_HUMAN" 2 811.4353 1.21 10182 5803 2 811.4346 406.7249 Histone deacetylase 6 OS=Homo sapiens OX=9606 GN=HDAC6 PE=1 SV=2 5.97 1789.7 - 397749 - - - -0.8935 - 1.438 0.13 - 136.5 1 2 0 -0.0007 8 0 0 0 1.60E+07 1.32E+07 - - - 1.0965 0.9993 221125_WJC_METTL3_EV_vs_WT_F02.05867.05867.2 0.0226 14-Jul R.VVAVSSVR[166.11].L sp|Q96H79|ZCCHL_HUMAN 1 825.4948 0.95 10191 5867 2 825.493977 413.7547 Zinc finger CCCH-type antiviral protein 1-like OS=Homo sapiens OX=9606 GN=ZC3HAV1L PE=1 SV=2 9.72 1800.1 - 469439 - - - -0.9631 - 1.621 0.322 - 220.1 1 2 0 -0.0008 8 0 0 0 2.37E+07 2.49E+07 - - - 2.8759 0.9996 221125_WJC_METTL3_EV_vs_WT_F02.05900.05900.2 0.00891 16-Sep R.VTDALNATR[166.11].A "sp|P10809|CH60_HUMAN,tr|A0A7I2V2X6|A0A7I2V2X6_HUMAN,tr|A0A7I2YQK6|A0A7I2YQK6_HUMAN,tr|A0A7I2V599|A0A7I2V599_HUMAN" 4 969.5119 1.38 10196 5900 2 969.511414 485.7632 "60 kDa heat shock protein, mitochondrial OS=Homo sapiens OX=9606 GN=HSPD1 PE=1 SV=2" 5.81 1805.5 - 386902 - - - -0.4796 - 1.956 0.321 - 306.1 1 2 0 -0.0005 9 0 0 0 3.05E+07 2.21E+07 - - - 3.3527 0.9936 221125_WJC_METTL3_EV_vs_WT_F02.05909.05909.3 0.0185 Aug-44 R.SQYEQLAEQNRK.D "sp|P13645|K1C10_HUMAN,tr|A0A1B0GVI3|A0A1B0GVI3_HUMAN" 2 1492.727 999 10197 5909 3 1492.721164 498.5829 "Keratin, type I cytoskeletal 10 OS=Homo sapiens OX=9606 GN=KRT10 PE=1 SV=6" 5.86 1807 - 177906 - - - -3.923 - 1.405 0.352 - 27.5 1 2 0 -0.0059 12 0 0 0 1.30E+07 0.00E+00 - - - 3.4054 0.9989 221125_WJC_METTL3_EV_vs_WT_F02.05911.05911.2 0.00347 16-Oct R.VTDALNATR.A "sp|P10809|CH60_HUMAN,tr|A0A7I2V2X6|A0A7I2V2X6_HUMAN,tr|A0A7I2YQK6|A0A7I2YQK6_HUMAN,tr|A0A7I2V599|A0A7I2V599_HUMAN" 4 959.5036 1.38 10198 5911 2 959.501998 480.7591 "60 kDa heat shock protein, mitochondrial OS=Homo sapiens OX=9606 GN=HSPD1 PE=1 SV=2" 5.81 1807.2 - 766931 - - - -1.679 - 1.716 0.296 - 299.5 1 2 0 -0.0016 9 0 0 0 3.05E+07 2.21E+07 - - - 2.789 0.9985 221125_WJC_METTL3_EV_vs_WT_F02.05917.05917.2 0.00193 20-Aug K.TPGPGAQSALR.A "sp|P62263|RS14_HUMAN,tr|A0A2R8Y811|A0A2R8Y811_HUMAN,tr|E5RH77|E5RH77_HUMAN" 3 1053.5567 1.42 10200 5917 2 1053.555495 527.7856 40S ribosomal protein S14 OS=Homo sapiens OX=9606 GN=RPS14 PE=1 SV=3 9.41 1808 - 134420 - - - -1.1504 - 1.64 0.253 - 92.3 1 2 0 -0.0012 11 0 0 0 9.28E+06 6.55E+06 - - - 2.2475 0.98 221125_WJC_METTL3_EV_vs_WT_F02.05981.05981.2 1.8 12-Jun K.VLIAQEK[136.11].M "sp|P30876|RPB2_HUMAN,tr|C9J4M6|C9J4M6_HUMAN,tr|C9J2Y9|C9J2Y9_HUMAN" 3 807.4946 1.06 10205 5981 2 807.494003 404.7546 DNA-directed RNA polymerase II subunit RPB2 OS=Homo sapiens OX=9606 GN=POLR2B PE=1 SV=1 5.97 1818.9 - 1.36E+06 - - - -0.6824 - 1.015 0.151 - 167.5 1 2 0 -0.0006 7 0 0 0 7.44E+07 7.05E+07 - - - 0.2033 0.9984 221125_WJC_METTL3_EV_vs_WT_F02.05987.05987.2 0.00883 12-Aug R.MAAPIDR[166.11].V "sp|P52272|HNRPM_HUMAN,tr|M0R2I7|M0R2I7_HUMAN,tr|A0A087X0X3|A0A087X0X3_HUMAN,tr|M0QZM1|M0QZM1_HUMAN" 4 782.3984 1.68 10206 5987 2 782.397917 392.2065 Heterogeneous nuclear ribonucleoprotein M OS=Homo sapiens OX=9606 GN=HNRNPM PE=1 SV=3 5.59 1819.8 - 854829 - - - -0.6544 - 1.705 0.176 - 436.4 1 2 0 -0.0005 7 0 0 0 1.91E+08 1.14E+08 - - - 2.0314 0.9993 221125_WJC_METTL3_EV_vs_WT_F02.05994.05994.2 0.755 12-Aug R.MAAPIDR.V "sp|P52272|HNRPM_HUMAN,tr|M0R2I7|M0R2I7_HUMAN,tr|A0A087X0X3|A0A087X0X3_HUMAN,tr|M0QZM1|M0QZM1_HUMAN" 4 772.3902 1.69 10207 5994 2 772.390588 387.2024 Heterogeneous nuclear ribonucleoprotein M OS=Homo sapiens OX=9606 GN=HNRNPM PE=1 SV=3 5.59 1821 - 2.00E+06 - - - 0.5554 - 1.929 0.232 - 408.2 1 2 0 0.0004 7 0 0 0 1.92E+08 1.14E+08 - - - 2.8362 0.9997 221125_WJC_METTL3_EV_vs_WT_F02.06003.06003.2 0.00074 12-Oct K.MVSGMVK[136.11].H sp|Q15046|SYK_HUMAN 1 758.391 0.001 10208 6003 2 758.390854 380.2028 Lysine--tRNA ligase OS=Homo sapiens OX=9606 GN=KARS1 PE=1 SV=3 8.5 1822.5 - 528777 - - - -0.2149 - 1.63 0.411 - 377.3 1 2 0 -0.0002 7 0 0 0 0.00E+00 2.68E+07 - - - 3.6247 0.9991 221125_WJC_METTL3_EV_vs_WT_F02.06043.06043.2 0.00615 20-May R.ADTQTYQPYNK.D sp|P84090|ERH_HUMAN 1 1327.6044 5.82 10215 6043 2 1327.604833 664.8095 Enhancer of rudimentary homolog OS=Homo sapiens OX=9606 GN=ERH PE=1 SV=1 5.88 1829 - 144800 - - - 0.2923 - 1.376 0.351 - 60.9 1 2 0 0.0004 11 0 0 0 6.75E+06 1.16E+06 - - - 2.4968 0.9486 221125_WJC_METTL3_EV_vs_WT_F02.06086.06086.2 0.474 14-Jun R.LVMAAANR[166.11].L "sp|P55084|ECHB_HUMAN,tr|F5GZQ3|F5GZQ3_HUMAN,tr|B5MD38|B5MD38_HUMAN" 3 854.4672 0.83 10223 6086 2 854.464054 428.2409 "Trifunctional enzyme subunit beta, mitochondrial OS=Homo sapiens OX=9606 GN=HADHB PE=1 SV=3" 9.75 1835.5 - 295170 - - - -3.6549 - 1.118 0.196 - 130.8 1 2 0 -0.0031 8 0 0 0 4.99E+07 6.00E+07 - - - 0.8241 0.9896 221125_WJC_METTL3_EV_vs_WT_F02.06102.06102.2 1.55 14-Jun R.LVMAAANR.L "sp|P55084|ECHB_HUMAN,tr|F5GZQ3|F5GZQ3_HUMAN,tr|B5MD38|B5MD38_HUMAN" 3 844.4589 0.75 10226 6102 2 844.457374 423.2367 "Trifunctional enzyme subunit beta, mitochondrial OS=Homo sapiens OX=9606 GN=HADHB PE=1 SV=3" 9.75 1838 - 918486 - - - -1.8154 - 1.283 0.168 - 154.9 1 2 0 -0.0015 8 0 0 0 5.01E+07 6.66E+07 - - - 1.0329 0.8432 221125_WJC_METTL3_EV_vs_WT_F02.06127.06127.2 4.62 12-Apr R.FMTDAAR.R "sp|Q86VZ6|JAZF1_HUMAN,tr|C9JGY8|C9JGY8_HUMAN,tr|H0Y403|H0Y403_HUMAN,tr|C9JWY1|C9JWY1_HUMAN" 4 810.3694 0.08 10231 6127 2 810.369079 406.192 Juxtaposed with another zinc finger protein 1 OS=Homo sapiens OX=9606 GN=JAZF1 PE=1 SV=2 5.84 1841.9 - 157761 - - - -0.4257 - 0.774 0.113 - 70.9 4 2 0 -0.0003 7 0 0 0 8.16E+06 1.06E+08 - - - -1.2052 0.9525 221125_WJC_METTL3_EV_vs_WT_F02.06256.06256.2 2.66 12-Jun K.ITPVTVK[136.11].A "sp|Q14978|NOLC1_HUMAN,tr|S4R3C2|S4R3C2_HUMAN,tr|A0A0A0MRM9|A0A0A0MRM9_HUMAN,tr|S4R349|S4R349_HUMAN" 4 764.4887 0.1 10251 6256 2 764.489178 383.2516 Nucleolar and coiled-body phosphoprotein 1 OS=Homo sapiens OX=9606 GN=NOLC1 PE=1 SV=2 8.75 1863.4 - 1.59E+06 - - - 0.5716 - 1.217 0 - 171.9 1 2 0 0.0004 7 0 0 0 7.18E+07 7.52E+08 - - - -0.3369 0.9582 221125_WJC_METTL3_EV_vs_WT_F02.06274.06274.2 2.2 12-Jun R.LALEAEK[136.11].V "sp|P54289|CA2D1_HUMAN,tr|E7ERK3|E7ERK3_HUMAN" 2 780.4473 1.28 10255 6274 2 780.44591 391.2309 Voltage-dependent calcium channel subunit alpha-2\delta-1 OS=Homo sapiens OX=9606 GN=CACNA2D1 PE=1 SV=3 4.53 1866.3 - 983291 - - - -1.7426 - 1.37 0.002 - 137.7 1 2 0 -0.0014 7 0 0 0 7.25E+07 5.66E+07 - - - 0.0528 0.8891 221125_WJC_METTL3_EV_vs_WT_F02.06296.06296.2 0.435 12-Jul S.LATQMVR.M "sp|P48643|TCPE_HUMAN,tr|E9PCA1|E9PCA1_HUMAN,tr|B7ZAR1|B7ZAR1_HUMAN,tr|E7ENZ3|E7ENZ3_HUMAN" 4 817.448 0.56 10261 6296 2 817.447356 409.7313 T-complex protein 1 subunit epsilon OS=Homo sapiens OX=9606 GN=CCT5 PE=1 SV=1 9.75 1869.6 - 464666 - - - -0.7976 - 1.448 0.221 - 141.3 1 1 0 -0.0007 7 0 0 0 1.46E+07 2.59E+07 - - - 1.846 0.9986 221125_WJC_METTL3_EV_vs_WT_F02.06376.06376.2 0.00103 14-Sep R.VGQAVALR.A "sp|Q13363|CTBP1_HUMAN,tr|H0Y9M9|H0Y9M9_HUMAN,tr|D6RAX2|D6RAX2_HUMAN,tr|H0Y8W7|H0Y8W7_HUMAN" 4 812.4868 0.05 10280 6376 2 812.485352 407.2507 C-terminal-binding protein 1 OS=Homo sapiens OX=9606 GN=CTBP1 PE=1 SV=2 9.72 1881.8 - 438771 - - - -1.8277 - 1.665 0.28 - 278.3 1 2 0 -0.0015 8 0 0 0 3.54E+07 6.56E+08 - - - 2.6462 0.8799 221125_WJC_METTL3_EV_vs_WT_F02.06378.06378.2 0.0315 12-Jun T.MGPALER.L "sp|P48995|TRPC1_HUMAN,sp|P52272|HNRPM_HUMAN,tr|M0R2I7|M0R2I7_HUMAN,tr|A0A087X0X3|A0A087X0X3_HUMAN,tr|M0QZM1|M0QZM1_HUMAN" 5 772.3902 1.67 10281 6378 2 772.388298 387.2024 Short transient receptor potential channel 1 OS=Homo sapiens OX=9606 GN=TRPC1 PE=1 SV=1 5.75 1882 - 1.08E+07 - - - -2.4094 - 1.34 0.355 - 216.2 1 1 0 -0.0019 7 0 0 0 1.38E+09 8.30E+08 - - - 2.5898 0.9994 221125_WJC_METTL3_EV_vs_WT_F02.06379.06379.2 0.00112 18-Jul K.YEELQQTAGR.H "sp|P13647|K2C5_HUMAN,tr|H0YI76|H0YI76_HUMAN,tr|H0YIN9|H0YIN9_HUMAN" 3 1193.5677 999 10282 6379 2 1193.564923 597.7911 "Keratin, type II cytoskeletal 5 OS=Homo sapiens OX=9606 GN=KRT5 PE=1 SV=3" 4.53 1882.2 - 99816.7 - - - -2.2982 - 1.668 0.456 - 121.8 1 2 0 -0.0027 10 0 0 0 4.16E+06 0.00E+00 - - - 3.8363 0.9622 221125_WJC_METTL3_EV_vs_WT_F02.06396.06396.2 0.947 14-May K.LGNPEIAR.R sp|P42773|CDN2C_HUMAN 1 868.4767 7.98 10284 6396 2 868.47446 435.2456 Cyclin-dependent kinase 4 inhibitor C OS=Homo sapiens OX=9606 GN=CDKN2C PE=1 SV=1 6 1884.9 - 235109 - - - -2.5401 - 1.095 0.159 - 61.5 1 2 0 -0.0022 8 0 0 0 1.09E+07 1.37E+06 - - - 0.4884 0.8751 221125_WJC_METTL3_EV_vs_WT_F02.06403.06403.2 5.37 12-Jun R.AMEALAR.R "sp|Q7L014|DDX46_HUMAN,tr|A0A0C4DG89|A0A0C4DG89_HUMAN" 2 760.3902 0.84 10285 6403 2 760.389147 381.2024 Probable ATP-dependent RNA helicase DDX46 OS=Homo sapiens OX=9606 GN=DDX46 PE=1 SV=2 6.05 1886.1 - 1.02E+06 - - - -1.3309 - 0.957 0.035 - 114.9 1 2 0 -0.001 7 0 0 0 6.54E+07 7.83E+07 - - - -0.8401 0.9996 221125_WJC_METTL3_EV_vs_WT_F02.06404.06404.3 2.05E-05 13/44 K.QR[166.11]YPDGIISK[136.11]PK[136.11].N sp|Q86U44|MTA70_HUMAN 1 1426.8143 0.001 10286 6404 3 1426.812417 476.612 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 9.7 1886.2 - 886641 - - - -1.298 - 1.761 0.485 - 191.5 1 2 1 -0.0019 12 0 0 0 0.00E+00 3.33E+07 - - - 5.5153 0.9989 221125_WJC_METTL3_EV_vs_WT_F02.06405.06405.2 0.00742 16-Sep K.SFQQSSLSR[166.11].D "sp|P43243|MATR3_HUMAN,tr|A0A1B0GX04|A0A1B0GX04_HUMAN,tr|D6RBS2|D6RBS2_HUMAN,tr|A8MXP9|A8MXP9_HUMAN,tr|D6R991|D6R991_HUMAN,tr|D6REK4|D6REK4_HUMAN,tr|D6R9F3|D6R9F3_HUMAN,tr|A0A0R4J2E8|A0A0R4J2E8_HUMAN,tr|D6RB45|D6RB45_HUMAN,tr|D6RCM3|D6RCM3_HUMAN,tr|D6R8Z5|D6R8Z5_HUMAN,tr|D6REM6|D6REM6_HUMAN" 12 1048.5177 1.2 10287 6405 2 1048.517065 525.2661 Matrin-3 OS=Homo sapiens OX=9606 GN=MATR3 PE=1 SV=2 9.47 1886.3 - 443006 - - - -0.5989 - 1.382 0.315 - 180.9 1 2 0 -0.0006 9 0 0 0 2.61E+07 2.17E+07 - - - 2.3034 0.7855 221125_WJC_METTL3_EV_vs_WT_F02.06429.06429.2 0.793 12-Aug T.MGPALER[166.11].L "sp|P48995|TRPC1_HUMAN,sp|P52272|HNRPM_HUMAN,tr|M0R2I7|M0R2I7_HUMAN,tr|A0A087X0X3|A0A087X0X3_HUMAN,tr|M0QZM1|M0QZM1_HUMAN" 5 782.3984 1.67 10292 6429 2 782.396041 392.2065 Short transient receptor potential channel 1 OS=Homo sapiens OX=9606 GN=TRPC1 PE=1 SV=1 5.75 1890.1 - 9.92E+06 - - - -3.0522 - 1.574 0.259 - 329.1 1 1 0 -0.0024 7 0 0 0 1.38E+09 8.30E+08 - - - 2.3905 0.8538 221125_WJC_METTL3_EV_vs_WT_F02.06442.06442.2 4.27 14-May K.LASDPALR.S "sp|Q9HB09|B2L12_HUMAN,tr|A0A087WSV0|A0A087WSV0_HUMAN" 2 841.4658 1.31 10297 6442 2 841.464238 421.7402 Bcl-2-like protein 12 OS=Homo sapiens OX=9606 GN=BCL2L12 PE=1 SV=1 5.84 1891.8 - 498205 - - - -1.8171 - 1.028 0.033 - 65.5 2 2 0 -0.0015 8 0 0 0 3.18E+07 2.42E+07 - - - -0.7669 0.9914 221125_WJC_METTL3_EV_vs_WT_F02.06504.06504.2 0.0304 14-Aug K.ALAPEYAK.A "sp|P07237|PDIA1_HUMAN,tr|A0A7P0TA97|A0A7P0TA97_HUMAN,tr|A0A7P0T8C0|A0A7P0T8C0_HUMAN,tr|H7BZ94|H7BZ94_HUMAN,tr|A0A7P0TA71|A0A7P0TA71_HUMAN,tr|I3L4M2|I3L4M2_HUMAN,tr|A0A7P0T9D6|A0A7P0T9D6_HUMAN,tr|H0Y3Z3|H0Y3Z3_HUMAN,tr|A0A7P0Z4S2|A0A7P0Z4S2_HUMAN,tr|I3NI03|I3NI03_HUMAN,tr|A0A7P0TA35|A0A7P0TA35_HUMAN,tr|A0A7P0TAX9|A0A7P0TAX9_HUMAN,tr|I3L514|I3L514_HUMAN,tr|A0A7P0Z476|A0A7P0Z476_HUMAN,tr|A0A7P0TBP8|A0A7P0TBP8_HUMAN,tr|A0A7P0TB26|A0A7P0TB26_HUMAN,tr|A0A7P0T9U6|A0A7P0T9U6_HUMAN,tr|I3L0S0|I3L0S0_HUMAN,tr|A0A7P0T8J3|A0A7P0T8J3_HUMAN,tr|A0A7P0Z4J0|A0A7P0Z4J0_HUMAN,tr|A0A7P0T9S9|A0A7P0T9S9_HUMAN,tr|A0A7P0T8X1|A0A7P0T8X1_HUMAN,tr|I3L3U6|I3L3U6_HUMAN" 23 861.4596 1.35 10308 6504 2 861.456139 431.7371 Protein disulfide-isomerase OS=Homo sapiens OX=9606 GN=P4HB PE=1 SV=3 6.05 1901.5 - 1.33E+06 - - - -4.0397 - 1.442 0.313 - 275.9 1 2 0 -0.0035 8 0 0 0 1.41E+08 1.05E+08 - - - 2.4557 0.9998 221125_WJC_METTL3_EV_vs_WT_F02.06536.06536.2 7.78E-05 24-Nov K.GPGEVAGTVTGQK[136.11].R "sp|Q86U44|MTA70_HUMAN,tr|F5H6D8|F5H6D8_HUMAN,tr|H0YFV6|H0YFV6_HUMAN,tr|B4DTN4|B4DTN4_HUMAN" 4 1207.6288 0.01 10313 6536 2 1207.627736 604.8217 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 6 1906.4 - 194789 - - - -0.8943 - 2.26 0.477 - 223.2 1 2 0 -0.0011 13 0 0 0 1.02E+06 1.90E+08 - - - 4.6564 0.9359 221125_WJC_METTL3_EV_vs_WT_F02.06545.06545.2 7.09 12-Jul K.VVEELTR.L "sp|Q16531|DDB1_HUMAN,sp|P62166|NCS1_HUMAN,tr|A0A7P0TAK7|A0A7P0TAK7_HUMAN,tr|A0A7P0T870|A0A7P0T870_HUMAN,tr|A0A7P0TB30|A0A7P0TB30_HUMAN,tr|A0A7P0Z3Z5|A0A7P0Z3Z5_HUMAN,tr|A0A7P0Z4B9|A0A7P0Z4B9_HUMAN,tr|A0A7P0T965|A0A7P0T965_HUMAN" 8 844.4654 0.33 10315 6545 2 844.463734 423.24 DNA damage-binding protein 1 OS=Homo sapiens OX=9606 GN=DDB1 PE=1 SV=1 4.53 1907.8 - 1.06E+06 - - - -2.0107 - 1.245 0.02 - 184.8 1 2 0 -0.0017 7 0 0 0 3.94E+07 1.21E+08 - - - -0.1175 0.9966 221125_WJC_METTL3_EV_vs_WT_F02.06561.06561.2 0.014 12-Jul K.VMLEDGR[166.11].S "sp|Q13310|PABP4_HUMAN,tr|A0A7I2V5W9|A0A7I2V5W9_HUMAN,tr|B1ANR0|B1ANR0_HUMAN,tr|A0A7I2V4L7|A0A7I2V4L7_HUMAN,tr|A0A7I2V598|A0A7I2V598_HUMAN,tr|A0A7I2V4V6|A0A7I2V4V6_HUMAN,tr|H0Y5F5|H0Y5F5_HUMAN" 7 828.4039 15.26 10318 6561 2 828.402475 415.2092 Polyadenylate-binding protein 4 OS=Homo sapiens OX=9606 GN=PABPC4 PE=1 SV=1 4.37 1910.3 - 6.00E+06 - - - -1.7298 - 1.442 0.22 - 264.8 1 2 0 -0.0014 7 0 0 0 4.65E+09 3.05E+08 - - - 1.8253 0.9983 221125_WJC_METTL3_EV_vs_WT_F02.06569.06569.2 0.00583 12-Jul K.VMLEDGR.S "sp|Q13310|PABP4_HUMAN,tr|A0A7I2V5W9|A0A7I2V5W9_HUMAN,tr|B1ANR0|B1ANR0_HUMAN,tr|A0A7I2V4L7|A0A7I2V4L7_HUMAN,tr|A0A7I2V598|A0A7I2V598_HUMAN,tr|A0A7I2V4V6|A0A7I2V4V6_HUMAN,tr|H0Y5F5|H0Y5F5_HUMAN" 7 818.3956 16.63 10320 6569 2 818.39464 410.2051 Polyadenylate-binding protein 4 OS=Homo sapiens OX=9606 GN=PABPC4 PE=1 SV=1 4.37 1911.5 - 7.72E+06 - - - -1.2195 - 1.414 0.27 - 233.5 1 2 0 -0.001 7 0 0 0 5.09E+09 3.06E+08 - - - 2.1326 0.9604 221125_WJC_METTL3_EV_vs_WT_F02.06570.06570.2 8.88 12-May K.YGADALR.L "sp|P41252|SYIC_HUMAN,tr|A0A804HL54|A0A804HL54_HUMAN,tr|A0A804HKU1|A0A804HKU1_HUMAN,tr|A0A804HK69|A0A804HK69_HUMAN,tr|A0A804HIV9|A0A804HIV9_HUMAN,tr|A0A804HJN6|A0A804HJN6_HUMAN,tr|A0A804HHW9|A0A804HHW9_HUMAN,tr|A0A0A0MSX9|A0A0A0MSX9_HUMAN,tr|J3KR24|J3KR24_HUMAN,tr|A0A804HJ36|A0A804HJ36_HUMAN" 10 764.3817 0.67 10321 6570 2 764.381923 383.1981 "Isoleucine--tRNA ligase, cytoplasmic OS=Homo sapiens OX=9606 GN=IARS1 PE=1 SV=2" 5.84 1911.6 - 1.51E+06 - - - 0.2878 - 1.159 0.049 - 60.5 2 2 0 0.0002 7 0 0 0 1.19E+08 1.79E+08 - - - -0.2641 0.9966 221125_WJC_METTL3_EV_vs_WT_F02.06577.06577.2 7.83 12-Jul K.YGADALR[166.11].L "sp|P41252|SYIC_HUMAN,tr|A0A804HL54|A0A804HL54_HUMAN,tr|A0A804HKU1|A0A804HKU1_HUMAN,tr|A0A804HK69|A0A804HK69_HUMAN,tr|A0A804HIV9|A0A804HIV9_HUMAN,tr|A0A804HJN6|A0A804HJN6_HUMAN,tr|A0A804HHW9|A0A804HHW9_HUMAN,tr|A0A0A0MSX9|A0A0A0MSX9_HUMAN,tr|J3KR24|J3KR24_HUMAN,tr|A0A804HJ36|A0A804HJ36_HUMAN" 10 774.39 0.66 10323 6577 2 774.389284 388.2023 "Isoleucine--tRNA ligase, cytoplasmic OS=Homo sapiens OX=9606 GN=IARS1 PE=1 SV=2" 5.84 1912.5 - 3.05E+06 - - - -0.8897 - 1.502 0.156 - 159.2 1 2 0 -0.0007 7 0 0 0 1.19E+08 1.80E+08 - - - 1.482 0.9045 221125_WJC_METTL3_EV_vs_WT_F02.06578.06578.2 0.266 12-Jun K.IMEAMEK[136.11].L "sp|Q9Y237|PIN4_HUMAN,tr|A0A494C021|A0A494C021_HUMAN,tr|H0Y610|H0Y610_HUMAN,tr|H0Y4T6|H0Y4T6_HUMAN,tr|H0Y8P6|H0Y8P6_HUMAN,tr|J3KMW3|J3KMW3_HUMAN" 6 858.4071 0.47 10324 6578 2 858.410031 430.2108 Peptidyl-prolyl cis-trans isomerase NIMA-interacting 4 OS=Homo sapiens OX=9606 GN=PIN4 PE=1 SV=1 4.53 1912.7 - 613942 - - - 3.4599 - 0.975 0.181 - 82 1 2 0 0.003 7 0 0 0 9.52E+06 2.03E+07 - - - 0.2967 0.9844 221125_WJC_METTL3_EV_vs_WT_F02.06587.06587.2 0.439 14-Jun R.VEEAIVAR[166.11].L sp|Q15050|RRS1_HUMAN 1 895.5003 1.43 10326 6587 2 895.499428 448.7574 Ribosome biogenesis regulatory protein homolog OS=Homo sapiens OX=9606 GN=RRS1 PE=1 SV=2 4.53 1914 - 242356 - - - -0.9202 - 1.275 0.087 - 135.9 1 2 0 -0.0008 8 0 0 0 1.66E+07 1.16E+07 - - - 0.416 0.9943 221125_WJC_METTL3_EV_vs_WT_F02.06606.06606.2 0.193 12-Jul K.VLNQELR.A "sp|P05090|APOD_HUMAN,tr|C9JF17|C9JF17_HUMAN,tr|C9JX71|C9JX71_HUMAN,tr|H0YDG4|H0YDG4_HUMAN" 4 870.4923 23.62 10330 6606 2 870.491113 436.2534 Apolipoprotein D OS=Homo sapiens OX=9606 GN=APOD PE=1 SV=1 5.97 1917.1 - 1.06E+06 - - - -1.382 - 1.419 0.153 - 256.8 1 2 0 -0.0012 7 0 0 0 1.25E+08 5.29E+06 - - - 1.2795 0.8746 221125_WJC_METTL3_EV_vs_WT_F02.06615.06615.2 0.268 12-Aug L.YVALAQR.K "sp|Q13310|PABP4_HUMAN,sp|Q9H361|PABP3_HUMAN,sp|Q4VXU2|PAP1L_HUMAN,sp|P11940|PABP1_HUMAN,tr|A0A7I2V5W9|A0A7I2V5W9_HUMAN,tr|H0YEU6|H0YEU6_HUMAN,tr|A0A7I2YQE4|A0A7I2YQE4_HUMAN,tr|A0A7I2V649|A0A7I2V649_HUMAN,tr|B1ANR0|B1ANR0_HUMAN,tr|A0A6Q8JFT6|A0A6Q8JFT6_HUMAN,tr|A0A7I2V4L7|A0A7I2V4L7_HUMAN,tr|H0YB86|H0YB86_HUMAN,tr|H0YAR2|H0YAR2_HUMAN,tr|E7ERJ7|E7ERJ7_HUMAN,tr|A0A7I2V598|A0A7I2V598_HUMAN,tr|A0A7I2YQ88|A0A7I2YQ88_HUMAN,tr|A0A7I2V4V6|A0A7I2V4V6_HUMAN,tr|H0Y5F5|H0Y5F5_HUMAN,tr|A0A6I8PIK9|A0A6I8PIK9_HUMAN,tr|A0A6I8PS38|A0A6I8PS38_HUMAN,tr|A0A6I8PLA1|A0A6I8PLA1_HUMAN,tr|A0A087WTT1|A0A087WTT1_HUMAN,tr|A0A7I2YQ90|A0A7I2YQ90_HUMAN,tr|A0A7I2V4N4|A0A7I2V4N4_HUMAN,tr|E7EQV3|E7EQV3_HUMAN" 25 819.4603 1.2 10332 6615 2 819.458767 410.7374 Polyadenylate-binding protein 4 OS=Homo sapiens OX=9606 GN=PABPC4 PE=1 SV=1 8.75 1918.4 - 1.32E+06 - - - -1.8549 - 1.599 0.226 - 263.1 1 1 0 -0.0015 7 0 0 0 1.02E+08 8.49E+07 - - - 2.197 0.9979 221125_WJC_METTL3_EV_vs_WT_F02.06624.06624.2 0.0755 16-Aug R.VLEAAVAAK[136.11].K "sp|Q14232|EI2BA_HUMAN,tr|F5H0D0|F5H0D0_HUMAN" 2 878.5317 0.5 10334 6624 2 878.529494 440.2731 Translation initiation factor eIF-2B subunit alpha OS=Homo sapiens OX=9606 GN=EIF2B1 PE=1 SV=1 5.97 1919.8 - 429215 - - - -2.4746 - 1.588 0.316 - 183.8 1 2 0 -0.0022 9 0 0 0 9.64E+06 1.91E+07 - - - 2.7123 0.9889 221125_WJC_METTL3_EV_vs_WT_F02.06632.06632.2 0.0875 14-Jun K.VAAAMPVR.A "sp|Q13573|SNW1_HUMAN,tr|G3V3A4|G3V3A4_HUMAN" 2 813.4531 0.93 10335 6632 2 813.450829 407.7338 SNW domain-containing protein 1 OS=Homo sapiens OX=9606 GN=SNW1 PE=1 SV=1 9.72 1921.1 - 537832 - - - -2.7844 - 1.208 0.255 - 122.2 1 2 0 -0.0023 8 0 0 0 8.70E+07 9.38E+07 - - - 1.4936 0.9982 221125_WJC_METTL3_EV_vs_WT_F02.06635.06635.2 0.0115 14-Oct K.VAAAMPVR[166.11].A "sp|Q13573|SNW1_HUMAN,tr|G3V3A4|G3V3A4_HUMAN" 2 823.4614 0.93 10336 6635 2 823.459199 412.738 SNW domain-containing protein 1 OS=Homo sapiens OX=9606 GN=SNW1 PE=1 SV=1 9.72 1921.5 - 901633 - - - -2.6291 - 2.049 0.239 - 425.4 1 2 0 -0.0022 8 0 0 0 8.70E+07 9.38E+07 - - - 2.9691 0.9939 221125_WJC_METTL3_EV_vs_WT_F02.06638.06638.2 0.231 12-Jun K.IIAPPER[166.11].K "sp|P63261|ACTG_HUMAN,sp|P68133|ACTS_HUMAN,sp|P62736|ACTA_HUMAN,sp|P68032|ACTC_HUMAN,sp|Q562R1|ACTBL_HUMAN,sp|P60709|ACTB_HUMAN,sp|P63267|ACTH_HUMAN,tr|A0A2R8YFE2|A0A2R8YFE2_HUMAN,tr|A0A804GS07|A0A804GS07_HUMAN,tr|A0A6Q8PFE4|A0A6Q8PFE4_HUMAN,tr|A0A804HKV3|A0A804HKV3_HUMAN,tr|I3L4N8|I3L4N8_HUMAN" 12 804.4733 1.08 10337 6638 2 804.472363 403.2439 "Actin, cytoplasmic 2 OS=Homo sapiens OX=9606 GN=ACTG1 PE=1 SV=1" 6 1921.9 - 5.62E+06 - - - -1.1747 - 1.272 0.182 - 139.6 1 2 0 -0.0009 7 0 0 0 3.94E+09 3.66E+09 - - - 1.1473 0.9981 221125_WJC_METTL3_EV_vs_WT_F02.06644.06644.2 0.0477 12-Jul K.VVGGFDR[166.11].V sp|P46087|NOP2_HUMAN 1 758.3951 0.001 10339 6644 2 758.394334 380.2048 Probable 28S rRNA (cytosine(4447)-C(5))-methyltransferase OS=Homo sapiens OX=9606 GN=NOP2 PE=1 SV=2 5.81 1922.8 - 830845 - - - -0.9546 - 1.193 0.32 - 145.1 1 2 0 -0.0007 7 0 0 0 0.00E+00 4.77E+07 - - - 1.9635 0.9993 221125_WJC_METTL3_EV_vs_WT_F02.06648.06648.2 0.0996 14-Aug R.GTLDPVEK[136.11].A "sp|P11142|HSP7C_HUMAN,tr|E9PNE6|E9PNE6_HUMAN,tr|A8K7Q2|A8K7Q2_HUMAN,tr|E9PKE3|E9PKE3_HUMAN,tr|E9PN89|E9PN89_HUMAN" 5 865.4636 0.22 10341 6648 2 865.462809 433.7391 Heat shock cognate 71 kDa protein OS=Homo sapiens OX=9606 GN=HSPA8 PE=1 SV=1 4.37 1923.3 - 887952 - - - -0.9694 - 1.805 0.275 - 269.2 1 2 0 -0.0008 8 0 0 0 1.30E+07 6.00E+07 - - - 2.853 0.9886 221125_WJC_METTL3_EV_vs_WT_F02.06660.06660.2 1.06 12-Jul K.IIAPPER.K "sp|P63261|ACTG_HUMAN,sp|P68133|ACTS_HUMAN,sp|P62736|ACTA_HUMAN,sp|P68032|ACTC_HUMAN,sp|Q562R1|ACTBL_HUMAN,sp|P60709|ACTB_HUMAN,sp|P63267|ACTH_HUMAN,tr|A0A2R8YFE2|A0A2R8YFE2_HUMAN,tr|A0A804GS07|A0A804GS07_HUMAN,tr|A0A6Q8PFE4|A0A6Q8PFE4_HUMAN,tr|A0A804HKV3|A0A804HKV3_HUMAN,tr|I3L4N8|I3L4N8_HUMAN" 12 794.465 1.08 10343 6660 2 794.464257 398.2398 "Actin, cytoplasmic 2 OS=Homo sapiens OX=9606 GN=ACTG1 PE=1 SV=1" 6 1925.2 - 3.68E+07 - - - -0.9831 - 1.395 0.075 - 193.4 1 2 0 -0.0008 7 0 0 0 3.94E+09 3.67E+09 - - - 0.6495 0.9777 221125_WJC_METTL3_EV_vs_WT_F02.06664.06664.2 1.69 12-Jul R.LGTDTLR[166.11].V "sp|Q2M296|MTHSD_HUMAN,tr|F5H0M7|F5H0M7_HUMAN" 2 784.4318 1.91 10345 6664 2 784.432075 393.2232 Methenyltetrahydrofolate synthase domain-containing protein OS=Homo sapiens OX=9606 GN=MTHFSD PE=1 SV=2 5.84 1925.8 - 531481 - - - 0.3021 - 1.316 0.027 - 116.6 1 2 0 0.0002 7 0 0 0 4.68E+07 2.45E+07 - - - 0.1104 0.9989 221125_WJC_METTL3_EV_vs_WT_F02.06686.06686.2 0.112 14-Sep K.LGVATVAK[136.11].G "sp|P49023|PAXI_HUMAN,tr|F5GZ78|F5GZ78_HUMAN,tr|A0A1B0GTU4|A0A1B0GTU4_HUMAN" 3 765.484 0.04 10348 6686 2 765.482282 383.7493 Paxillin OS=Homo sapiens OX=9606 GN=PXN PE=1 SV=3 8.75 1929.3 - 738199 - - - -2.2313 - 1.942 0.284 - 177.3 1 2 0 -0.0017 8 0 0 0 1.34E+06 2.98E+07 - - - 3.1398 0.993 221125_WJC_METTL3_EV_vs_WT_F02.06693.06693.2 0.0421 14-Sep K.VVALAEGR[166.11].E "sp|Q8N6T3|ARFG1_HUMAN,tr|F8VWB3|F8VWB3_HUMAN,tr|F8VWH9|F8VWH9_HUMAN,tr|E5RHT6|E5RHT6_HUMAN,tr|F8W1U7|F8W1U7_HUMAN,tr|E5RHC5|E5RHC5_HUMAN" 6 823.4791 1.6 10350 6693 2 823.476572 412.7468 ADP-ribosylation factor GTPase-activating protein 1 OS=Homo sapiens OX=9606 GN=ARFGAP1 PE=1 SV=2 5.97 1930.3 - 2.57E+06 - - - -3.0966 - 1.776 0.19 - 338.7 2 2 0 -0.0026 8 0 0 0 1.85E+08 1.16E+08 - - - 2.0413 0.9742 221125_WJC_METTL3_EV_vs_WT_F02.06694.06694.2 0.0258 14-Jun K.VVALAEGR.E "sp|Q8N6T3|ARFG1_HUMAN,tr|F8VWB3|F8VWB3_HUMAN,tr|F8VWH9|F8VWH9_HUMAN,tr|E5RHT6|E5RHT6_HUMAN,tr|F8W1U7|F8W1U7_HUMAN,tr|E5RHC5|E5RHC5_HUMAN" 6 813.4709 1.6 10351 6694 2 814.475473 407.7427 ADP-ribosylation factor GTPase-activating protein 1 OS=Homo sapiens OX=9606 GN=ARFGAP1 PE=1 SV=2 5.97 1930.3 - 4.41E+06 - - - 1234.9809 - 1.454 0.474 - 103.4 1 2 0 1.0046 8 0 0 0 1.85E+08 1.16E+08 - - - 3.3554 0.8835 221125_WJC_METTL3_EV_vs_WT_F02.06700.06700.2 0.00767 14-Sep K.LGVATVAK.G "sp|P49023|PAXI_HUMAN,tr|F5GZ78|F5GZ78_HUMAN,tr|A0A1B0GTU4|A0A1B0GTU4_HUMAN" 3 757.4698 0.04 10352 6700 2 758.470643 379.7422 Paxillin OS=Homo sapiens OX=9606 GN=PXN PE=1 SV=3 8.75 1931.2 - 150444 - - - 1321.3108 - 1.67 0.353 - 173.3 1 2 0 1.0009 8 0 0 0 1.34E+06 2.98E+07 - - - 2.8806 0.9998 221125_WJC_METTL3_EV_vs_WT_F02.06705.06705.2 0.0015 14-Aug K.VVALAEGR.E "sp|Q8N6T3|ARFG1_HUMAN,tr|F8VWB3|F8VWB3_HUMAN,tr|F8VWH9|F8VWH9_HUMAN,tr|E5RHT6|E5RHT6_HUMAN,tr|F8W1U7|F8W1U7_HUMAN,tr|E5RHC5|E5RHC5_HUMAN" 6 813.4709 1.6 10354 6705 2 813.471217 407.7427 ADP-ribosylation factor GTPase-activating protein 1 OS=Homo sapiens OX=9606 GN=ARFGAP1 PE=1 SV=2 5.97 1931.9 - 3.97E+06 - - - 0.4487 - 1.671 0.513 - 257.1 1 2 0 0.0004 8 0 0 0 1.85E+08 1.16E+08 - - - 4.3784 1 221125_WJC_METTL3_EV_vs_WT_F02.06740.06740.2 4.71E-06 15/24 K.GPGEVAGTVTGQK[136.11].R "sp|Q86U44|MTA70_HUMAN,tr|F5H6D8|F5H6D8_HUMAN,tr|H0YFV6|H0YFV6_HUMAN,tr|B4DTN4|B4DTN4_HUMAN" 4 1207.6288 0.01 10367 6740 2 1207.628277 604.8217 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 6 1936.6 - 680890 - - - -0.4463 - 2.804 0.615 - 961.5 1 2 0 -0.0005 13 0 0 0 1.02E+06 1.90E+08 - - - 6.2294 0.9243 221125_WJC_METTL3_EV_vs_WT_F02.06754.06754.2 2.57 12-Jun K.LYATMEK.H "sp|Q92793|CBP_HUMAN,sp|Q09472|EP300_HUMAN,tr|A0A669KB12|A0A669KB12_HUMAN" 3 854.4208 1.12 10371 6754 2 854.418831 428.2177 CREB-binding protein OS=Homo sapiens OX=9606 GN=CREBBP PE=1 SV=3 6 1938.6 - 415862 - - - -2.2928 - 0.998 0.117 - 84.5 1 2 0 -0.002 7 0 0 0 2.23E+07 1.99E+07 - - - -0.1018 0.9936 221125_WJC_METTL3_EV_vs_WT_F02.06756.06756.2 0.818 12-Jun R.FSGVPDR.F "sp|A0A075B6R9|KVD24_HUMAN,sp|A0A0C4DH68|KV224_HUMAN,sp|A2NJV5|KV229_HUMAN,sp|A0A075B6S2|KVD29_HUMAN,sp|A0A0A0MRZ7|KVD26_HUMAN" 5 776.3817 22.99 10372 6756 2 776.380184 389.1981 Probable non-functional immunoglobulin kappa variable 2D-24 OS=Homo sapiens OX=9606 GN=IGKV2D-24 PE=1 SV=1 5.84 1938.8 - 1.93E+06 - - - -1.9565 - 1.187 0.255 - 122.8 1 2 0 -0.0015 7 0 0 0 5.81E+08 2.53E+07 - - - 1.4671 0.9688 221125_WJC_METTL3_EV_vs_WT_F02.06762.06762.2 0.197 12-May R.IMDQTLK.A "tr|F5H7S3|F5H7S3_HUMAN,tr|H0YKX5|H0YKX5_HUMAN,tr|H0YL42|H0YL42_HUMAN,tr|B7Z596|B7Z596_HUMAN,tr|H7BYY1|H7BYY1_HUMAN" 5 847.4473 0.82 10375 6762 2 847.44427 424.7309 Tropomyosin alpha-1 chain OS=Homo sapiens OX=9606 GN=TPM1 PE=1 SV=2 5.84 1939.5 - 148337 - - - -3.6226 - 1.233 0.199 - 72.6 1 2 0 -0.0031 7 0 0 0 3.04E+07 3.69E+07 - - - 1.1735 0.945 221125_WJC_METTL3_EV_vs_WT_F02.06770.06770.2 0.317 14-Aug R.VGQDPVLR.Q "sp|Q04837|SSBP_HUMAN,tr|C9K0U8|C9K0U8_HUMAN,tr|A0A0G2JLD8|A0A0G2JLD8_HUMAN,tr|E7EUY5|E7EUY5_HUMAN" 4 882.4923 1.53 10376 6770 2 882.48785 442.2534 "Single-stranded DNA-binding protein, mitochondrial OS=Homo sapiens OX=9606 GN=SSBP1 PE=1 SV=1" 5.81 1940.8 - 776431 - - - -5.0607 - 1.409 0.194 - 249.7 1 2 0 -0.0045 8 0 0 0 2.07E+08 1.35E+08 - - - 1.5066 0.8144 221125_WJC_METTL3_EV_vs_WT_F02.06778.06778.2 0.0352 14-Jul R.VGQDPVLR[166.11].Q "sp|Q04837|SSBP_HUMAN,tr|C9K0U8|C9K0U8_HUMAN,tr|A0A0G2JLD8|A0A0G2JLD8_HUMAN,tr|E7EUY5|E7EUY5_HUMAN" 4 892.5006 1.53 10379 6778 2 892.495679 447.2576 "Single-stranded DNA-binding protein, mitochondrial OS=Homo sapiens OX=9606 GN=SSBP1 PE=1 SV=1" 5.81 1941.9 - 1.00E+06 - - - -5.498 - 1.124 0.184 - 105.7 1 2 0 -0.0049 8 0 0 0 2.07E+08 1.35E+08 - - - 0.751 0.937 221125_WJC_METTL3_EV_vs_WT_F02.06780.06780.2 1.89 12-Jul R.LEEEALR[166.11].R "sp|Q8WUD4|CCD12_HUMAN,tr|C9JUN5|C9JUN5_HUMAN,tr|J3KR35|J3KR35_HUMAN,tr|S4R331|S4R331_HUMAN" 4 868.453 4.66 10380 6780 2 868.4567 435.2338 Coiled-coil domain-containing protein 12 OS=Homo sapiens OX=9606 GN=CCDC12 PE=1 SV=1 4.25 1942.1 - 577938 - - - 4.2984 - 1.576 0.073 - 179.4 1 2 0 0.0037 7 0 0 0 3.11E+08 6.67E+07 - - - 1.0204 0.9996 221125_WJC_METTL3_EV_vs_WT_F02.06811.06811.2 0.0382 18-Aug K.AEAESLYQSK.Y sp|P04264|K2C1_HUMAN 1 1124.535 32.06 10386 6811 2 1124.534934 563.2748 "Keratin, type II cytoskeletal 1 OS=Homo sapiens OX=9606 GN=KRT1 PE=1 SV=6" 4.53 1946.9 - 265956 - - - -0.0311 - 1.87 0.352 - 149.1 1 2 0 0 10 0 0 0 1.34E+07 4.18E+05 - - - 3.388 0.9976 221125_WJC_METTL3_EV_vs_WT_F02.06820.06820.2 1.17 12-Aug R.MGPVMDR[166.11].M "sp|P52272|HNRPM_HUMAN,tr|M0R2I7|M0R2I7_HUMAN,tr|A0A087X0X3|A0A087X0X3_HUMAN,tr|M0QZM1|M0QZM1_HUMAN" 4 814.3705 1.59 10388 6820 2 814.369852 408.1925 Heterogeneous nuclear ribonucleoprotein M OS=Homo sapiens OX=9606 GN=HNRNPM PE=1 SV=3 5.59 1948.2 - 773245 - - - -0.7957 - 1.535 0.182 - 338.1 1 2 0 -0.0006 7 0 0 0 1.57E+09 9.90E+08 - - - 1.7429 0.9965 221125_WJC_METTL3_EV_vs_WT_F02.06828.06828.2 0.285 14-Jun K.ILVAEGTR[166.11].D "sp|P10515|ODP2_HUMAN,tr|A0A7P0TBE2|A0A7P0TBE2_HUMAN,tr|A0A7P0Z4G4|A0A7P0Z4G4_HUMAN,tr|A0A7P0TAX2|A0A7P0TAX2_HUMAN,tr|A0A7P0T9N8|A0A7P0T9N8_HUMAN,tr|E9PEJ4|E9PEJ4_HUMAN,tr|A0A7P0Z423|A0A7P0Z423_HUMAN,tr|A0A7P0TAG1|A0A7P0TAG1_HUMAN,tr|A0A7P0T997|A0A7P0T997_HUMAN,tr|A0A7P0Z459|A0A7P0Z459_HUMAN" 10 867.5053 0.82 10391 6828 2 867.505747 434.7599 "Dihydrolipoyllysine-residue acetyltransferase component of pyruvate dehydrogenase complex, mitochondrial OS=Homo sapiens OX=9606 GN=DLAT PE=1 SV=3" 6 1949.3 - 1.71E+06 - - - 0.4726 - 1.383 0.189 - 95.8 1 2 0 0.0004 8 0 0 0 1.35E+08 1.64E+08 - - - 1.4148 0.9962 221125_WJC_METTL3_EV_vs_WT_F02.06829.06829.2 0.426 12-Aug R.IGVITNR[166.11].E sp|P62701|RS4X_HUMAN 1 781.4686 0.95 10392 6829 2 781.467984 391.7416 "40S ribosomal protein S4, X isoform OS=Homo sapiens OX=9606 GN=RPS4X PE=1 SV=2" 9.75 1949.4 - 914808 - - - -0.7332 - 1.553 0.125 - 196.2 1 2 0 -0.0006 7 0 0 0 4.01E+09 4.23E+09 - - - 1.3588 0.9988 221125_WJC_METTL3_EV_vs_WT_F02.06832.06832.2 0.00189 12-Aug R.MGPVMDR.M "sp|P52272|HNRPM_HUMAN,tr|M0R2I7|M0R2I7_HUMAN,tr|A0A087X0X3|A0A087X0X3_HUMAN,tr|M0QZM1|M0QZM1_HUMAN" 4 804.3622 1.59 10393 6832 2 804.362574 403.1884 Heterogeneous nuclear ribonucleoprotein M OS=Homo sapiens OX=9606 GN=HNRNPM PE=1 SV=3 5.59 1949.8 - 2.45E+06 - - - 0.4277 - 1.514 0.26 - 278.5 1 2 0 0.0003 7 0 0 0 1.57E+09 9.90E+08 - - - 2.2754 0.9943 221125_WJC_METTL3_EV_vs_WT_F02.06833.06833.2 0.269 12-Jul R.IGVITNR.E sp|P62701|RS4X_HUMAN 1 771.4603 0.95 10394 6833 2 771.46041 386.7374 "40S ribosomal protein S4, X isoform OS=Homo sapiens OX=9606 GN=RPS4X PE=1 SV=2" 9.75 1949.9 - 884316 - - - 0.1594 - 1.705 0.039 - 147.2 1 2 0 0.0001 7 0 0 0 4.01E+09 4.23E+09 - - - 1.0196 0.9976 221125_WJC_METTL3_EV_vs_WT_F02.06836.06836.2 0.665 14-Jul K.ILVAEGTR.D "sp|P10515|ODP2_HUMAN,tr|A0A7P0TBE2|A0A7P0TBE2_HUMAN,tr|A0A7P0Z4G4|A0A7P0Z4G4_HUMAN,tr|A0A7P0TAX2|A0A7P0TAX2_HUMAN,tr|A0A7P0T9N8|A0A7P0T9N8_HUMAN,tr|E9PEJ4|E9PEJ4_HUMAN,tr|A0A7P0Z423|A0A7P0Z423_HUMAN,tr|A0A7P0TAG1|A0A7P0TAG1_HUMAN,tr|A0A7P0T997|A0A7P0T997_HUMAN,tr|A0A7P0Z459|A0A7P0Z459_HUMAN" 10 857.4971 0.83 10395 6836 2 857.496985 429.7558 "Dihydrolipoyllysine-residue acetyltransferase component of pyruvate dehydrogenase complex, mitochondrial OS=Homo sapiens OX=9606 GN=DLAT PE=1 SV=3" 6 1950.3 - 1.70E+06 - - - -0.0956 - 1.62 0.153 - 136.3 1 2 0 -0.0001 8 0 0 0 1.35E+08 1.63E+08 - - - 1.626 1 221125_WJC_METTL3_EV_vs_WT_F02.06837.06837.2 5.25E-08 14/24 R.EVATNSELVQSGK.S "sp|Q04695|K1C17_HUMAN,sp|P02533|K1C14_HUMAN,tr|K7ESE1|K7ESE1_HUMAN,tr|F5GWP8|F5GWP8_HUMAN" 4 1360.6834 9.51 10396 6837 2 1360.676386 681.349 "Keratin, type I cytoskeletal 17 OS=Homo sapiens OX=9606 GN=KRT17 PE=1 SV=2" 4.53 1950.4 - 114336 - - - -5.1724 - 2.532 0.659 - 596.4 1 2 0 -0.007 13 0 0 0 1.59E+07 1.67E+06 - - - 6.2905 0.928 221125_WJC_METTL3_EV_vs_WT_F02.06852.06852.2 8.56 14-Jun R.SPALPGGR[166.11].S "sp|O15553|MEFV_HUMAN,tr|F5H595|F5H595_HUMAN,tr|F5H6N9|F5H6N9_HUMAN,tr|F5H2E5|F5H2E5_HUMAN,tr|I3L0S7|I3L0S7_HUMAN" 5 763.4216 0.001 10399 6852 2 763.421249 382.7181 Pyrin OS=Homo sapiens OX=9606 GN=MEFV PE=1 SV=1 9.47 1952.9 - 4.30E+06 - - - -0.4689 - 1.184 0 - 165 3 2 0 -0.0004 8 0 0 0 0.00E+00 1.72E+08 - - - -0.6629 0.9972 221125_WJC_METTL3_EV_vs_WT_F02.06856.06856.2 0.0961 14-Aug K.VAPVIAPK.L sp|Q96T58|MINT_HUMAN 1 793.5062 1.3 10401 6856 2 793.505307 397.7604 Msx2-interacting protein OS=Homo sapiens OX=9606 GN=SPEN PE=1 SV=1 8.72 1953.3 - 1.80E+06 - - - -1.0939 - 1.273 0.26 - 307.8 1 2 0 -0.0009 8 0 0 0 2.45E+08 1.88E+08 - - - 1.6891 0.9998 221125_WJC_METTL3_EV_vs_WT_F02.06906.06906.2 0.00103 26-Aug R.GNLGAGNGNLQGPR.H "sp|P43243|MATR3_HUMAN,tr|D6RE02|D6RE02_HUMAN,tr|B3KM87|B3KM87_HUMAN,tr|A8MXP9|A8MXP9_HUMAN,tr|D6RAY2|D6RAY2_HUMAN,tr|D6R991|D6R991_HUMAN,tr|A0A0R4J2E8|A0A0R4J2E8_HUMAN,tr|D6RAM9|D6RAM9_HUMAN,tr|D6RIA2|D6RIA2_HUMAN,tr|H0Y8T4|H0Y8T4_HUMAN,tr|D6REM6|D6REM6_HUMAN,tr|D6RBI2|D6RBI2_HUMAN" 12 1323.6644 2.07 10408 6906 2 1323.664934 662.8395 Matrin-3 OS=Homo sapiens OX=9606 GN=MATR3 PE=1 SV=2 9.75 1961.5 - 114630 - - - 0.4336 - 1.891 0.455 - 94.1 1 2 0 0.0006 14 0 0 0 2.37E+07 1.14E+07 - - - 4.0002 0.841 221125_WJC_METTL3_EV_vs_WT_F02.06923.06923.2 0.181 14-Jun A.PLGGSGFK.G sp|C9JH25|PRRT4_HUMAN 1 761.4072 1.27 10412 6923 2 761.407458 381.7109 Proline-rich transmembrane protein 4 OS=Homo sapiens OX=9606 GN=PRRT4 PE=2 SV=1 9.18 1964 - 867224 - - - 0.3533 - 1.211 0.281 - 80.1 3 1 0 0.0003 8 0 0 0 4.79E+07 3.78E+07 - - - 1.4806 0.9946 221125_WJC_METTL3_EV_vs_WT_F02.06924.06924.2 0.317 16-Aug R.LAAGSAIVK[136.11].L sp|Q9NTI5|PDS5B_HUMAN 1 836.5211 2.99 10413 6924 2 836.520079 419.2678 Sister chromatid cohesion protein PDS5 homolog B OS=Homo sapiens OX=9606 GN=PDS5B PE=1 SV=1 8.75 1964.2 - 324281 - - - -1.2241 - 1.365 0.178 - 122 1 2 0 -0.001 9 0 0 0 4.16E+07 1.39E+07 - - - 1.2556 0.9999 221125_WJC_METTL3_EV_vs_WT_F02.06935.06935.2 1.12E-05 26-Dec R.GNLGAGNGNLQGPR[166.11].H "sp|P43243|MATR3_HUMAN,tr|D6RE02|D6RE02_HUMAN,tr|B3KM87|B3KM87_HUMAN,tr|A8MXP9|A8MXP9_HUMAN,tr|D6RAY2|D6RAY2_HUMAN,tr|D6R991|D6R991_HUMAN,tr|A0A0R4J2E8|A0A0R4J2E8_HUMAN,tr|D6RAM9|D6RAM9_HUMAN,tr|D6RIA2|D6RIA2_HUMAN,tr|H0Y8T4|H0Y8T4_HUMAN,tr|D6REM6|D6REM6_HUMAN,tr|D6RBI2|D6RBI2_HUMAN" 12 1333.6726 2.04 10416 6935 2 1333.67257 667.8436 Matrin-3 OS=Homo sapiens OX=9606 GN=MATR3 PE=1 SV=2 9.75 1965.9 - 184174 - - - -0.045 - 2.58 0.445 - 314.3 1 2 0 -0.0001 14 0 0 0 2.34E+07 1.14E+07 - - - 4.7062 0.9987 221125_WJC_METTL3_EV_vs_WT_F02.06957.06957.2 0.0177 14-Jul K.AAALEAMK[136.11].D "sp|P31948|STIP1_HUMAN,tr|H0YGI8|H0YGI8_HUMAN" 2 811.4353 1.46 10422 6957 2 811.434597 406.7249 Stress-induced-phosphoprotein 1 OS=Homo sapiens OX=9606 GN=STIP1 PE=1 SV=1 6.05 1969.2 - 442984 - - - -0.8972 - 1.435 0.285 - 161.9 1 2 0 -0.0007 8 0 0 0 3.00E+07 2.05E+07 - - - 2.235 0.9994 221125_WJC_METTL3_EV_vs_WT_F02.06970.06970.2 0.00287 14-Nov K.VGEVIVTK.D "sp|P10809|CH60_HUMAN,tr|A0A7I2V2X6|A0A7I2V2X6_HUMAN,tr|A0A7I2YQK6|A0A7I2YQK6_HUMAN,tr|A0A7I2V599|A0A7I2V599_HUMAN" 4 843.5066 1.23 10427 6970 2 843.50457 422.7606 "60 kDa heat shock protein, mitochondrial OS=Homo sapiens OX=9606 GN=HSPD1 PE=1 SV=2" 5.97 1971 - 1.11E+06 - - - -2.3699 - 2.301 0.327 - 366 1 2 0 -0.002 8 0 0 0 3.81E+10 3.09E+10 - - - 3.9689 0.9982 221125_WJC_METTL3_EV_vs_WT_F02.06973.06973.2 0.303 14-Sep R.VVLAPEEK[136.11].E "sp|P39880|CUX1_HUMAN,sp|O14529|CUX2_HUMAN,tr|A0A2R8Y852|A0A2R8Y852_HUMAN,tr|A0A2R8YDI1|A0A2R8YDI1_HUMAN" 4 891.5157 1.44 10430 6973 2 891.513539 446.7651 Homeobox protein cut-like 1 OS=Homo sapiens OX=9606 GN=CUX1 PE=1 SV=3 4.53 1971.2 - 1.81E+06 - - - -2.406 - 1.66 0.305 - 297 1 2 0 -0.0021 8 0 0 0 4.51E+08 3.14E+08 - - - 2.8216 0.998 221125_WJC_METTL3_EV_vs_WT_F02.06977.06977.2 0.178 14-Sep K.VGEVIVTK[136.11].D "sp|P10809|CH60_HUMAN,tr|A0A7I2V2X6|A0A7I2V2X6_HUMAN,tr|A0A7I2YQK6|A0A7I2YQK6_HUMAN,tr|A0A7I2V599|A0A7I2V599_HUMAN" 4 851.5208 1.23 10432 6977 2 851.518203 426.7677 "60 kDa heat shock protein, mitochondrial OS=Homo sapiens OX=9606 GN=HSPD1 PE=1 SV=2" 5.97 1971.7 - 5.31E+06 - - - -3.0134 - 1.969 0.276 - 231.6 1 2 0 -0.0026 8 0 0 0 3.81E+10 3.09E+10 - - - 3.1221 0.9083 221125_WJC_METTL3_EV_vs_WT_F02.06982.06982.2 1.37 12-Jun R.LTPDPYR[166.11].M sp|P18583|SON_HUMAN 1 870.4475 1.14 10434 6982 2 870.444549 436.231 Protein SON OS=Homo sapiens OX=9606 GN=SON PE=1 SV=4 5.84 1972.3 - 3.43E+06 - - - -3.3764 - 1.095 0.128 - 168.8 1 2 0 -0.0029 7 0 0 0 3.11E+08 2.73E+08 - - - 0.273 0.9909 221125_WJC_METTL3_EV_vs_WT_F02.06985.06985.2 0.731 12-Aug K.LEEMVTR.L "sp|Q99816|TS101_HUMAN,tr|F5H442|F5H442_HUMAN" 2 876.4375 1.29 10435 6985 2 876.436197 439.226 Tumor susceptibility gene 101 protein OS=Homo sapiens OX=9606 GN=TSG101 PE=1 SV=2 4.53 1972.7 - 873583 - - - -1.4901 - 1.449 0.104 - 245.3 1 2 0 -0.0013 7 0 0 0 5.70E+07 4.43E+07 - - - 0.9839 0.998 221125_WJC_METTL3_EV_vs_WT_F02.07002.07002.2 0.00505 14-Aug R.VVLAPEEK.E "sp|P39880|CUX1_HUMAN,sp|O14529|CUX2_HUMAN,tr|A0A2R8Y852|A0A2R8Y852_HUMAN,tr|A0A2R8YDI1|A0A2R8YDI1_HUMAN" 4 883.5015 1.44 10438 7002 2 883.498673 442.758 Homeobox protein cut-like 1 OS=Homo sapiens OX=9606 GN=CUX1 PE=1 SV=3 4.53 1975.4 - 1.01E+07 - - - -3.1817 - 1.44 0.424 - 249.1 1 2 0 -0.0028 8 0 0 0 4.51E+08 3.14E+08 - - - 3.2715 0.9384 221125_WJC_METTL3_EV_vs_WT_F02.07010.07010.2 5.73 14-Jun R.LIVGTAGR[166.11].R "sp|O43684|BUB3_HUMAN,tr|J3QT28|J3QT28_HUMAN" 2 795.4842 0.58 10440 7010 2 795.481635 398.7494 Mitotic checkpoint protein BUB3 OS=Homo sapiens OX=9606 GN=BUB3 PE=1 SV=1 9.75 1976.5 - 4.38E+06 - - - -3.2345 - 1.186 0.126 - 98.5 1 2 0 -0.0026 8 0 0 0 2.01E+08 3.47E+08 - - - 0.4853 0.9448 221125_WJC_METTL3_EV_vs_WT_F02.07032.07032.2 1.68 14-Jun R.LIVGTAGR.R "sp|O43684|BUB3_HUMAN,tr|J3QT28|J3QT28_HUMAN" 2 785.4759 0.58 10446 7032 2 785.473148 393.7452 Mitotic checkpoint protein BUB3 OS=Homo sapiens OX=9606 GN=BUB3 PE=1 SV=1 9.75 1979.7 - 4.14E+06 - - - -3.552 - 1.289 0.124 - 94.8 1 2 0 -0.0028 8 0 0 0 2.01E+08 3.47E+08 - - - 0.7216 0.9976 221125_WJC_METTL3_EV_vs_WT_F02.07034.07034.2 0.437 16-Oct R.VLAAVQAAR[166.11].N sp|Q9NU22|MDN1_HUMAN 1 907.5479 0.55 10447 7034 2 907.545133 454.7812 Midasin OS=Homo sapiens OX=9606 GN=MDN1 PE=1 SV=2 9.72 1979.9 - 902928 - - - -3.0158 - 2.065 0.248 - 226.8 1 2 0 -0.0027 9 0 0 0 9.01E+06 1.63E+07 - - - 2.9697 0.9987 221125_WJC_METTL3_EV_vs_WT_F02.07080.07080.2 0.000487 12-Jun R.YVDEVVR[166.11].N "sp|P49585|PCY1A_HUMAN,tr|H7C1T3|H7C1T3_HUMAN,tr|C9J050|C9J050_HUMAN,tr|C9JEJ2|C9JEJ2_HUMAN,tr|C9J2E1|C9J2E1_HUMAN,tr|H7BZN1|H7BZN1_HUMAN" 6 888.4581 1.21 10455 7080 2 888.457864 445.2363 Choline-phosphate cytidylyltransferase A OS=Homo sapiens OX=9606 GN=PCYT1A PE=1 SV=2 4.37 1986.8 - 631186 - - - -0.2116 - 1.29 0.311 - 132.9 1 2 0 -0.0002 7 0 0 0 4.29E+07 3.54E+07 - - - 2.1448 0.9914 221125_WJC_METTL3_EV_vs_WT_F02.07087.07087.2 0.00804 12-Jul R.YVDEVVR.N "sp|P49585|PCY1A_HUMAN,tr|H7C1T3|H7C1T3_HUMAN,tr|C9J050|C9J050_HUMAN,tr|C9JEJ2|C9JEJ2_HUMAN,tr|C9J2E1|C9J2E1_HUMAN,tr|H7BZN1|H7BZN1_HUMAN" 6 878.4498 0.94 10457 7087 2 878.446794 440.2322 Choline-phosphate cytidylyltransferase A OS=Homo sapiens OX=9606 GN=PCYT1A PE=1 SV=2 4.37 1987.9 - 660989 - - - -3.4014 - 1.273 0.305 - 177.4 1 2 0 -0.003 7 0 0 0 4.31E+07 4.60E+07 - - - 2.0576 0.9289 221125_WJC_METTL3_EV_vs_WT_F02.07104.07104.2 2.22 12-Aug K.SSLMVAR[166.11].S "sp|Q9ULX6|AKP8L_HUMAN,tr|A0A7P0TAE3|A0A7P0TAE3_HUMAN" 2 772.4141 1.37 10460 7104 2 772.410845 387.2143 A-kinase anchor protein 8-like OS=Homo sapiens OX=9606 GN=AKAP8L PE=1 SV=4 9.47 1990.5 - 1.40E+06 - - - -4.1869 - 1.356 0.115 - 175.7 1 2 0 -0.0032 7 0 0 0 8.22E+07 6.00E+07 - - - 0.8543 0.9994 221125_WJC_METTL3_EV_vs_WT_F02.07177.07177.2 0.0126 16-Sep K.GPLATGGIK[136.11].K "sp|Q9Y2S6|TMA7_HUMAN,tr|A0A024R1R8|A0A024R1R8_HUMAN" 2 820.4898 0.53 10473 7177 2 820.489652 411.2522 Translation machinery-associated protein 7 OS=Homo sapiens OX=9606 GN=TMA7 PE=1 SV=1 8.75 2001.9 - 990960 - - - -0.184 - 1.675 0.319 - 329.4 1 2 0 -0.0002 9 0 0 0 8.05E+07 1.52E+08 - - - 2.8894 0.9925 221125_WJC_METTL3_EV_vs_WT_F02.07178.07178.2 1.64 14-Aug K.VGEVIVTK[136.11].D "sp|P10809|CH60_HUMAN,tr|A0A7I2V2X6|A0A7I2V2X6_HUMAN,tr|A0A7I2YQK6|A0A7I2YQK6_HUMAN,tr|A0A7I2V599|A0A7I2V599_HUMAN" 4 851.5208 1.75 10474 7178 2 851.519775 426.7677 "60 kDa heat shock protein, mitochondrial OS=Homo sapiens OX=9606 GN=HSPD1 PE=1 SV=2" 5.97 2002 - 436375 - - - -1.1673 - 1.476 0.105 - 187.5 1 2 0 -0.001 8 0 0 0 9.14E+07 5.22E+07 - - - 0.9904 0.9961 221125_WJC_METTL3_EV_vs_WT_F02.07206.07206.2 0.362 12-Aug R.ISSIYAR.E "sp|Q14683|SMC1A_HUMAN,tr|G8JLG1|G8JLG1_HUMAN,tr|A0A6Q8PHC3|A0A6Q8PHC3_HUMAN,tr|V9GY57|V9GY57_HUMAN" 4 808.4443 0.93 10480 7206 2 808.44501 405.2294 Structural maintenance of chromosomes protein 1A OS=Homo sapiens OX=9606 GN=SMC1A PE=1 SV=2 8.75 2006.3 - 2.71E+06 - - - 0.8745 - 1.716 0.094 - 187.6 1 2 0 0.0007 7 0 0 0 1.50E+08 1.61E+08 - - - 1.4461 0.9902 221125_WJC_METTL3_EV_vs_WT_F02.07210.07210.2 0.95 12-Aug R.ISSIYAR[166.11].E "sp|Q14683|SMC1A_HUMAN,tr|G8JLG1|G8JLG1_HUMAN,tr|A0A6Q8PHC3|A0A6Q8PHC3_HUMAN,tr|V9GY57|V9GY57_HUMAN" 4 818.4526 0.93 10482 7210 2 818.453766 410.2336 Structural maintenance of chromosomes protein 1A OS=Homo sapiens OX=9606 GN=SMC1A PE=1 SV=2 8.75 2006.8 - 3.46E+06 - - - 1.4576 - 1.512 0.086 - 187.1 1 2 0 0.0012 7 0 0 0 1.49E+08 1.61E+08 - - - 0.9858 0.9983 221125_WJC_METTL3_EV_vs_WT_F02.07220.07220.2 0.0599 16-Aug K.GPLATGGIK.K "sp|Q9Y2S6|TMA7_HUMAN,tr|A0A024R1R8|A0A024R1R8_HUMAN" 2 812.4756 0.53 10485 7220 2 812.474155 407.2451 Translation machinery-associated protein 7 OS=Homo sapiens OX=9606 GN=TMA7 PE=1 SV=1 8.75 2008.2 - 1.79E+06 - - - -1.7822 - 1.624 0.274 - 246.6 1 2 0 -0.0014 9 0 0 0 8.05E+07 1.51E+08 - - - 2.4671 0.9329 221125_WJC_METTL3_EV_vs_WT_F02.07236.07236.2 2.32 14-Apr K.VLEDSDLK[136.11].K "sp|P11021|BIP_HUMAN,tr|A0A7P0TB36|A0A7P0TB36_HUMAN" 2 925.4848 1.01 10489 7236 2 925.484181 463.7497 Endoplasmic reticulum chaperone BiP OS=Homo sapiens OX=9606 GN=HSPA5 PE=1 SV=2 4.03 2010.7 - 97498.2 - - - -0.644 - 0.763 0.16 - 45.6 1 2 0 -0.0006 8 0 0 0 5.73E+06 5.65E+06 - - - -0.5932 0.8829 221125_WJC_METTL3_EV_vs_WT_F02.07237.07237.2 6.02 12-Apr K.VPVVVC[160.03]R[166.11].D "sp|Q5TAX3|TUT4_HUMAN,sp|Q5VYS8|TUT7_HUMAN,tr|Q5VYT0|Q5VYT0_HUMAN,tr|E9PKY2|E9PKY2_HUMAN,tr|A0A0C4DFM7|A0A0C4DFM7_HUMAN,tr|E9PKX1|E9PKX1_HUMAN" 6 837.477 0.75 10490 7237 2 837.476757 419.7458 Terminal uridylyltransferase 4 OS=Homo sapiens OX=9606 GN=TUT4 PE=1 SV=3 8.22 2010.8 - 165639 - - - -0.3069 - 0.892 0.11 - 50.5 13 2 0 -0.0003 7 0 0 0 1.25E+07 1.66E+07 - - - -1.0064 0.9343 221125_WJC_METTL3_EV_vs_WT_F02.07257.07257.2 7.22 12-Jun K.LTSLNVK[136.11].Y "sp|O95758|PTBP3_HUMAN,sp|P26599|PTBP1_HUMAN,sp|Q8WXD9|CSKI1_HUMAN,tr|A0A6Q8PEX4|A0A6Q8PEX4_HUMAN,tr|A0A0U1RRM4|A0A0U1RRM4_HUMAN,tr|A6NLN1|A6NLN1_HUMAN,tr|A0A087WU68|A0A087WU68_HUMAN,tr|A0A7I2V4H6|A0A7I2V4H6_HUMAN,tr|A0A7I2V621|A0A7I2V621_HUMAN,tr|K7EK45|K7EK45_HUMAN" 10 781.4789 1.1 10496 7257 2 781.478164 391.7467 Polypyrimidine tract-binding protein 3 OS=Homo sapiens OX=9606 GN=PTBP3 PE=1 SV=2 8.75 2013.8 - 373558 - - - -0.9469 - 1.014 0.072 - 68.4 2 2 0 -0.0007 7 0 0 0 1.65E+07 1.50E+07 - - - -0.5179 0.9619 221125_WJC_METTL3_EV_vs_WT_F02.07266.07266.2 0.0144 12-Aug R.PLMAEPR.G "sp|P33240|CSTF2_HUMAN,tr|E9PID8|E9PID8_HUMAN,tr|E7EWR4|E7EWR4_HUMAN" 3 812.4215 2.86 10499 7266 2 812.420405 407.218 Cleavage stimulation factor subunit 2 OS=Homo sapiens OX=9606 GN=CSTF2 PE=1 SV=1 6.43 2015.1 - 1.99E+06 - - - -1.2974 - 1.471 0.38 - 265.9 1 1 0 -0.0011 7 0 0 0 2.54E+08 8.88E+07 - - - 3.0702 0.8995 221125_WJC_METTL3_EV_vs_WT_F02.07275.07275.2 0.0551 12-Aug R.PLMAEPR[166.11].G "sp|P33240|CSTF2_HUMAN,tr|E9PID8|E9PID8_HUMAN,tr|E7EWR4|E7EWR4_HUMAN" 3 822.4297 2.86 10503 7275 2 822.428454 412.2221 Cleavage stimulation factor subunit 2 OS=Homo sapiens OX=9606 GN=CSTF2 PE=1 SV=1 6.43 2016.3 - 1.63E+06 - - - -1.5503 - 1.555 0.244 - 284.1 1 1 0 -0.0013 7 0 0 0 2.53E+08 8.87E+07 - - - 2.2416 0.9645 221125_WJC_METTL3_EV_vs_WT_F02.07285.07285.2 8.66 12-Jul K.LLSVAEK[136.11].H "sp|Q96F86|EDC3_HUMAN,tr|H3BSQ0|H3BSQ0_HUMAN,tr|H3BPN4|H3BPN4_HUMAN" 3 766.468 0.26 10507 7285 2 766.466685 384.2413 Enhancer of mRNA-decapping protein 3 OS=Homo sapiens OX=9606 GN=EDC3 PE=1 SV=1 6 2017.6 - 865568 - - - -1.7222 - 1.343 0.024 - 127.4 1 2 0 -0.0013 7 0 0 0 1.50E+07 5.85E+07 - - - 0.1523 0.9962 221125_WJC_METTL3_EV_vs_WT_F02.07287.07287.2 0.664 14-Jun R.VLVPATDR.N "sp|P60228|EIF3E_HUMAN,tr|A0A7I2V3I2|A0A7I2V3I2_HUMAN,tr|H0YBP5|H0YBP5_HUMAN,tr|A0A7I2V5Z6|A0A7I2V5Z6_HUMAN,tr|A0A7I2V2H9|A0A7I2V2H9_HUMAN,tr|B3KW56|B3KW56_HUMAN,tr|A0A7I2V4B4|A0A7I2V4B4_HUMAN,tr|E5RGA2|E5RGA2_HUMAN,tr|A0A7I2V3I0|A0A7I2V3I0_HUMAN,tr|A0A7I2V3S3|A0A7I2V3S3_HUMAN,tr|A0A7I2V4G3|A0A7I2V4G3_HUMAN,tr|A0A7I2V2W0|A0A7I2V2W0_HUMAN,tr|A0A7I2V5P9|A0A7I2V5P9_HUMAN" 13 869.4971 1.5 10508 7287 2 869.496598 435.7558 Eukaryotic translation initiation factor 3 subunit E OS=Homo sapiens OX=9606 GN=EIF3E PE=1 SV=1 5.81 2017.9 - 6.83E+06 - - - -0.5394 - 1.46 0.155 - 132.6 1 2 0 -0.0005 8 0 0 0 3.61E+08 2.40E+08 - - - 1.327 0.9222 221125_WJC_METTL3_EV_vs_WT_F02.07301.07301.2 1.52 16-Jul K.LAAGLAGLR[166.11].W sp|Q75VX8|GARE2_HUMAN 1 850.5264 0.001 10512 7301 2 850.524166 426.2705 GRB2-associated and regulator of MAPK protein 2 OS=Homo sapiens OX=9606 GN=GAREM2 PE=1 SV=3 9.75 2019.8 - 837234 - - - -2.6348 - 1.245 0.078 - 204.2 3 2 0 -0.0022 9 0 0 0 0.00E+00 7.59E+08 - - - 0.0372 0.9953 221125_WJC_METTL3_EV_vs_WT_F02.07326.07326.2 0.42 14-Jul R.VIEC[160.03]DVVK.D "sp|Q96PK6|RBM14_HUMAN,tr|B8ZZ74|B8ZZ74_HUMAN,tr|F8WDX3|F8WDX3_HUMAN,tr|A0A0A0MSL8|A0A0A0MSL8_HUMAN,tr|A0A0A6YYI9|A0A0A6YYI9_HUMAN" 5 960.495 5.83 10519 7326 2 960.495315 481.2548 RNA-binding protein 14 OS=Homo sapiens OX=9606 GN=RBM14 PE=1 SV=2 4.37 2023.4 - 623518 - - - 0.3092 - 1.3 0.182 - 161.9 1 2 0 0.0003 8 0 0 0 2.11E+07 3.62E+06 - - - 1.1764 0.9582 221125_WJC_METTL3_EV_vs_WT_F02.07330.07330.2 11.1 12-Jun K.LDPYVQR.L "sp|Q14204|DYHC1_HUMAN,tr|A0A7P0T8N2|A0A7P0T8N2_HUMAN,tr|A0A7P0T9C4|A0A7P0T9C4_HUMAN,tr|A0A7P0TBJ7|A0A7P0TBJ7_HUMAN,tr|A0A804HHY6|A0A804HHY6_HUMAN,tr|A0A7P0T9K2|A0A7P0T9K2_HUMAN,tr|A0A7P0TB64|A0A7P0TB64_HUMAN,tr|A0A2R8Y706|A0A2R8Y706_HUMAN,tr|A0A7P0T916|A0A7P0T916_HUMAN,tr|A0A7P0TB75|A0A7P0TB75_HUMAN,tr|A0A7P0T8W5|A0A7P0T8W5_HUMAN,tr|A0A7P0T9S3|A0A7P0T9S3_HUMAN,tr|A0A7P0TAF3|A0A7P0TAF3_HUMAN,tr|A0A7P0T9F1|A0A7P0T9F1_HUMAN,tr|A0A7P0TAW9|A0A7P0TAW9_HUMAN,tr|A0A2R8YGC7|A0A2R8YGC7_HUMAN,tr|A0A7P0TA13|A0A7P0TA13_HUMAN,tr|A0A7P0T934|A0A7P0T934_HUMAN,tr|A0A7P0TAV5|A0A7P0TAV5_HUMAN,tr|A0A7P0T9Y3|A0A7P0T9Y3_HUMAN,tr|A0A7P0T7V5|A0A7P0T7V5_HUMAN,tr|A0A7P0T9R4|A0A7P0T9R4_HUMAN,tr|A0A2R8Y5T0|A0A2R8Y5T0_HUMAN,tr|A0A7P0T990|A0A7P0T990_HUMAN,tr|A0A7P0T942|A0A7P0T942_HUMAN,tr|A0A2R8YFZ7|A0A2R8YFZ7_HUMAN,tr|A0A7P0T825|A0A7P0T825_HUMAN,tr|A0A2R8Y6H2|A0A2R8Y6H2_HUMAN,tr|A0A7P0TBC9|A0A7P0TBC9_HUMAN,tr|A0A7P0TAM4|A0A7P0TAM4_HUMAN" 30 889.4658 0.94 10521 7330 2 889.465845 445.7402 Cytoplasmic dynein 1 heavy chain 1 OS=Homo sapiens OX=9606 GN=DYNC1H1 PE=1 SV=5 5.84 2023.8 - 672860 - - - 0.0877 - 0.947 0.11 - 116.2 1 2 0 0.0001 7 0 0 0 3.58E+07 3.80E+07 - - - -0.3191 0.9641 221125_WJC_METTL3_EV_vs_WT_F02.07331.07331.2 0.0626 14-Jun R.ISPATTLR.K sp|Q8IVW6|ARI3B_HUMAN 1 857.4971 0.48 10522 7331 2 857.501352 429.7558 AT-rich interactive domain-containing protein 3B OS=Homo sapiens OX=9606 GN=ARID3B PE=1 SV=2 9.75 2023.9 - 460054 - - - 4.9971 - 1.307 0.27 - 102.2 1 2 0 0.0043 8 0 0 0 3.11E+07 6.54E+07 - - - 1.8413 0.9603 221125_WJC_METTL3_EV_vs_WT_F02.07348.07348.2 3.36 16-May K.VLDSGAPIK[136.11].L "sp|P06576|ATPB_HUMAN,tr|F8W079|F8W079_HUMAN,tr|H0YH81|H0YH81_HUMAN" 3 906.5266 2.49 10526 7348 2 906.52743 454.2706 "ATP synthase subunit beta, mitochondrial OS=Homo sapiens OX=9606 GN=ATP5F1B PE=1 SV=3" 5.81 2026.5 - 175302 - - - 0.9343 - 1.176 0.085 - 93.3 4 2 0 0.0008 9 0 0 0 9.56E+07 3.83E+07 - - - -0.1314 0.9972 221125_WJC_METTL3_EV_vs_WT_F02.07352.07352.2 0.285 14-Jul R.ISPATTLR[166.11].K sp|Q8IVW6|ARI3B_HUMAN 1 867.5053 0.62 10528 7352 2 867.507219 434.7599 AT-rich interactive domain-containing protein 3B OS=Homo sapiens OX=9606 GN=ARID3B PE=1 SV=2 9.75 2027.1 - 621972 - - - 2.1694 - 1.534 0.267 - 174.4 1 2 0 0.0019 8 0 0 0 3.07E+07 4.96E+07 - - - 2.3029 0.9965 221125_WJC_METTL3_EV_vs_WT_F02.07360.07360.2 0.387 14-Aug R.VLLGETGK[136.11].E "sp|P62280|RS11_HUMAN,tr|M0QZC5|M0QZC5_HUMAN,tr|M0R1H6|M0R1H6_HUMAN" 3 823.4895 0.95 10531 7360 2 823.489343 412.752 40S ribosomal protein S11 OS=Homo sapiens OX=9606 GN=RPS11 PE=1 SV=3 5.97 2028.2 - 1.41E+06 - - - -0.153 - 1.398 0.176 - 141.8 1 2 0 -0.0001 8 0 0 0 4.13E+09 4.34E+09 - - - 1.3514 0.9965 221125_WJC_METTL3_EV_vs_WT_F02.07362.07362.2 0.115 14-Jul R.VLLGETGK.E "sp|P62280|RS11_HUMAN,tr|M0QZC5|M0QZC5_HUMAN,tr|M0R1H6|M0R1H6_HUMAN" 3 815.4753 0.95 10532 7362 2 815.476506 408.7449 40S ribosomal protein S11 OS=Homo sapiens OX=9606 GN=RPS11 PE=1 SV=3 5.97 2028.4 - 860590 - - - 1.5169 - 1.142 0.317 - 157.1 1 2 0 0.0012 8 0 0 0 4.13E+09 4.34E+09 - - - 1.7824 0.9048 221125_WJC_METTL3_EV_vs_WT_F02.07364.07364.2 0.0688 12-Jul A.GDVAFIR[166.11].E "sp|P02788|TRFL_HUMAN,tr|E7EQB2|E7EQB2_HUMAN,tr|E7ER44|E7ER44_HUMAN" 3 786.4264 1.55 10534 7364 2 786.426412 394.2205 Lactotransferrin OS=Homo sapiens OX=9606 GN=LTF PE=1 SV=6 5.84 2028.6 - 601939 - - - 0.0687 - 1.336 0.263 - 197 1 1 0 0.0001 7 0 0 0 8.38E+07 5.41E+07 - - - 1.9014 0.8578 221125_WJC_METTL3_EV_vs_WT_F02.07367.07367.2 7.73 12-May R.MYSYPAR.V "sp|P07910|HNRPC_HUMAN,tr|B4DY08|B4DY08_HUMAN,tr|G3V575|G3V575_HUMAN,tr|G3V5V7|G3V5V7_HUMAN,tr|B2R5W2|B2R5W2_HUMAN,tr|G3V4C1|G3V4C1_HUMAN,tr|G3V576|G3V576_HUMAN,tr|G3V2D6|G3V2D6_HUMAN,tr|G3V4W0|G3V4W0_HUMAN,tr|G3V555|G3V555_HUMAN,tr|G3V2Q1|G3V2Q1_HUMAN" 11 886.4007 1.35 10535 7367 2 886.400506 444.2076 Heterogeneous nuclear ribonucleoproteins C1\C2 OS=Homo sapiens OX=9606 GN=HNRNPC PE=1 SV=4 8.34 2029.1 - 451303 - - - -0.2459 - 0.855 0.042 - 102.1 1 2 0 -0.0002 7 0 0 0 9.66E+07 7.16E+07 - - - -1.1452 0.9993 221125_WJC_METTL3_EV_vs_WT_F02.07369.07369.2 0.00478 16-Sep K.VLDSGAPIK.L "sp|P06576|ATPB_HUMAN,tr|F8W079|F8W079_HUMAN,tr|H0YH81|H0YH81_HUMAN" 3 898.5124 2.42 10536 7369 2 898.513062 450.2635 "ATP synthase subunit beta, mitochondrial OS=Homo sapiens OX=9606 GN=ATP5F1B PE=1 SV=3" 5.81 2029.3 - 583867 - - - 0.7557 - 1.518 0.347 - 221 1 2 0 0.0007 9 0 0 0 9.17E+07 3.79E+07 - - - 2.8113 0.9991 221125_WJC_METTL3_EV_vs_WT_F02.07371.07371.2 0.0291 16-Jul K.VDPEIQNVK.A sp|P35908|K22E_HUMAN 1 1040.5502 215.7 10537 7371 2 1040.550084 521.2824 "Keratin, type II cytoskeletal 2 epidermal OS=Homo sapiens OX=9606 GN=KRT2 PE=1 SV=2" 4.37 2029.5 - 686457 - - - -0.1355 - 1.622 0.269 - 127.2 1 2 0 -0.0001 9 0 0 0 2.91E+07 1.35E+05 - - - 2.427 0.9615 221125_WJC_METTL3_EV_vs_WT_F02.07385.07385.2 2.3 12-May R.LITAYQR.S "sp|Q9P2D1|CHD7_HUMAN,sp|Q3L8U1|CHD9_HUMAN,tr|H3BTW3|H3BTW3_HUMAN,tr|A0A087WU44|A0A087WU44_HUMAN" 4 863.4865 0.91 10539 7385 2 863.486742 432.7505 Chromodomain-helicase-DNA-binding protein 7 OS=Homo sapiens OX=9606 GN=CHD7 PE=1 SV=3 8.75 2031.9 - 424770 - - - 0.2779 - 0.916 0.134 - 76.5 1 2 0 0.0002 7 0 0 0 7.93E+07 8.69E+07 - - - -0.2474 0.999 221125_WJC_METTL3_EV_vs_WT_F02.07415.07415.2 0.00126 14-Sep R.VGFAEAAR[166.11].L "sp|P07339|CATD_HUMAN,tr|A0A1B0GW44|A0A1B0GW44_HUMAN,tr|A0A1B0GVD5|A0A1B0GVD5_HUMAN,tr|A0A1B0GV23|A0A1B0GV23_HUMAN,tr|C9JH19|C9JH19_HUMAN,tr|A0A1B0GWE8|A0A1B0GWE8_HUMAN,tr|A0A1B0GVP3|A0A1B0GVP3_HUMAN,tr|F8W787|F8W787_HUMAN" 8 829.4322 7.8 10551 7415 2 829.429807 415.7234 Cathepsin D OS=Homo sapiens OX=9606 GN=CTSD PE=1 SV=1 5.97 2036 - 1.10E+06 - - - -2.8513 - 1.762 0.419 - 234.3 1 2 0 -0.0024 8 0 0 0 4.09E+08 5.24E+07 - - - 3.8434 0.999 221125_WJC_METTL3_EV_vs_WT_F02.07430.07430.2 0.0833 12-Jul R.MYSYPAR[166.11].V "sp|P07910|HNRPC_HUMAN,tr|B4DY08|B4DY08_HUMAN,tr|G3V575|G3V575_HUMAN,tr|G3V5V7|G3V5V7_HUMAN,tr|B2R5W2|B2R5W2_HUMAN,tr|G3V4C1|G3V4C1_HUMAN,tr|G3V576|G3V576_HUMAN,tr|G3V2D6|G3V2D6_HUMAN,tr|G3V4W0|G3V4W0_HUMAN,tr|G3V555|G3V555_HUMAN,tr|G3V2Q1|G3V2Q1_HUMAN" 11 896.409 1.35 10557 7430 2 896.407685 449.2118 Heterogeneous nuclear ribonucleoproteins C1\C2 OS=Homo sapiens OX=9606 GN=HNRNPC PE=1 SV=4 8.34 2037.9 - 710267 - - - -1.4603 - 1.294 0.393 - 244.5 1 2 0 -0.0013 7 0 0 0 9.81E+07 7.28E+07 - - - 2.7599 0.9924 221125_WJC_METTL3_EV_vs_WT_F02.07433.07433.2 2.17 14-Jun R.LGVTGNIK[136.11].L sp|Q05655|KPCD_HUMAN 1 808.4898 2.54 10558 7433 2 808.490448 405.2522 Protein kinase C delta type OS=Homo sapiens OX=9606 GN=PRKCD PE=1 SV=2 8.75 2038.3 - 326251 - - - 0.7978 - 1.166 0.195 - 61.5 1 2 0 0.0006 8 0 0 0 3.10E+07 1.22E+07 - - - 0.9443 0.9942 221125_WJC_METTL3_EV_vs_WT_F02.07437.07437.2 0.518 12-Jul K.MITSLSK[136.11].D "sp|P49736|MCM2_HUMAN,tr|H0Y8E6|H0Y8E6_HUMAN" 2 786.4401 0.95 10560 7437 2 786.442231 394.2273 DNA replication licensing factor MCM2 OS=Homo sapiens OX=9606 GN=MCM2 PE=1 SV=4 8.5 2038.8 - 399970 - - - 2.7402 - 1.356 0.271 - 187.9 1 2 0 0.0022 7 0 0 0 2.08E+07 2.18E+07 - - - 2.0069 0.9806 221125_WJC_METTL3_EV_vs_WT_F02.07444.07444.2 3.51 12-Jun R.EVVTEIR[166.11].D "sp|Q9ULX3|NOB1_HUMAN,tr|H3BUR4|H3BUR4_HUMAN" 2 854.4737 0.81 10562 7444 2 854.471286 428.2441 RNA-binding protein NOB1 OS=Homo sapiens OX=9606 GN=NOB1 PE=1 SV=1 4.53 2039.8 - 420087 - - - -2.8275 - 1.443 0.122 - 213 1 2 0 -0.0024 7 0 0 0 6.73E+07 8.27E+07 - - - 1.1033 0.9375 221125_WJC_METTL3_EV_vs_WT_F02.07467.07467.2 0.59 12-May K.NDAGIQR[166.11].C "sp|Q8WZ42|TITIN_HUMAN,tr|A0A0A0MTS7|A0A0A0MTS7_HUMAN" 2 782.391 1.21 10567 7467 2 782.390962 392.2028 Titin OS=Homo sapiens OX=9606 GN=TTN PE=1 SV=4 5.84 2043.2 - 769901 - - - -0.0933 - 1.173 0 - 63.2 2 2 0 -0.0001 7 0 0 0 1.79E+07 1.49E+07 - - - -0.5879 0.9937 221125_WJC_METTL3_EV_vs_WT_F02.07480.07480.2 0.464 12-Jun K.TPPVVIK[136.11].S sp|Q96A49|SYAP1_HUMAN 1 760.4938 0.001 10574 7480 2 760.49378 381.2542 Synapse-associated protein 1 OS=Homo sapiens OX=9606 GN=SYAP1 PE=1 SV=1 8.41 2044.8 - 1.05E+06 - - - -0.0605 - 1.089 0.219 - 96.3 1 2 0 0 7 0 0 0 0.00E+00 1.16E+09 - - - 0.9287 0.9982 221125_WJC_METTL3_EV_vs_WT_F02.07490.07490.2 0.107 12-Jun R.LTGDAFR.K sp|O95881|TXD12_HUMAN 1 778.3974 1.18 10578 7490 2 778.396041 390.206 Thioredoxin domain-containing protein 12 OS=Homo sapiens OX=9606 GN=TXNDC12 PE=1 SV=1 5.84 2046.3 - 1.87E+07 - - - -1.6855 - 1.45 0.29 - 143.9 1 2 0 -0.0013 7 0 0 0 2.27E+09 1.93E+09 - - - 2.3598 0.9507 221125_WJC_METTL3_EV_vs_WT_F02.07492.07492.2 16.2 12-Jun K.VIVNSLK.N "sp|Q13510|ASAH1_HUMAN,tr|A0A1B0GUE3|A0A1B0GUE3_HUMAN,tr|A0A1B0GUH5|A0A1B0GUH5_HUMAN,tr|A0A1B0GUA4|A0A1B0GUA4_HUMAN,tr|A0A1B0GVA3|A0A1B0GVA3_HUMAN,tr|A0A1B0GTM3|A0A1B0GTM3_HUMAN,tr|A0A1B0GW66|A0A1B0GW66_HUMAN,tr|A0A1B0GW68|A0A1B0GW68_HUMAN,tr|A0A1B0GUB3|A0A1B0GUB3_HUMAN,tr|A0A1B0GU62|A0A1B0GU62_HUMAN,tr|A0A1B0GVE7|A0A1B0GVE7_HUMAN,tr|A0A1B0GUJ3|A0A1B0GUJ3_HUMAN,tr|A0A1B0GTZ5|A0A1B0GTZ5_HUMAN,tr|A0A1B0GUW4|A0A1B0GUW4_HUMAN,tr|E7EMM4|E7EMM4_HUMAN,tr|A0A1B0GVG2|A0A1B0GVG2_HUMAN,tr|A0A1B0GTP7|A0A1B0GTP7_HUMAN,tr|A0A1B0GV95|A0A1B0GV95_HUMAN,tr|A0A1B0GVJ1|A0A1B0GVJ1_HUMAN,tr|A0A1B0GW48|A0A1B0GW48_HUMAN,tr|A0A1B0GU06|A0A1B0GU06_HUMAN" 21 771.4854 19.26 10579 7492 2 771.484312 386.75 Acid ceramidase OS=Homo sapiens OX=9606 GN=ASAH1 PE=1 SV=5 8.72 2046.5 - 531324 - - - -1.4621 - 1 0.107 - 68.4 1 2 0 -0.0011 7 0 0 0 1.83E+07 9.51E+05 - - - -0.1691 0.9989 221125_WJC_METTL3_EV_vs_WT_F02.07496.07496.2 0.000571 16-Aug R.LVASMEEAR.R "sp|Q15149|PLEC_HUMAN,tr|H0YDN1|H0YDN1_HUMAN" 2 1004.4961 1.98 10580 7496 2 1004.49336 503.2553 Plectin OS=Homo sapiens OX=9606 GN=PLEC PE=1 SV=3 4.53 2047.1 - 449085 - - - -2.7088 - 1.536 0.44 - 221.4 1 2 0 -0.0027 9 0 0 0 6.63E+07 3.35E+07 - - - 3.5316 0.9974 221125_WJC_METTL3_EV_vs_WT_F02.07500.07500.2 0.203 12-Jul R.LTGDAFR[166.11].K sp|O95881|TXD12_HUMAN 1 788.4056 1.18 10582 7500 2 788.403557 395.2101 Thioredoxin domain-containing protein 12 OS=Homo sapiens OX=9606 GN=TXNDC12 PE=1 SV=1 5.84 2047.5 - 3.28E+07 - - - -2.6205 - 1.625 0.272 - 159.3 1 2 0 -0.0021 7 0 0 0 2.27E+09 1.93E+09 - - - 2.5877 0.9423 221125_WJC_METTL3_EV_vs_WT_F02.07503.07503.2 0.316 16-Aug R.LVASMEEAR[166.11].R "sp|Q15149|PLEC_HUMAN,tr|H0YDN1|H0YDN1_HUMAN" 2 1014.5044 1.98 10585 7503 2 1014.499889 508.2595 Plectin OS=Homo sapiens OX=9606 GN=PLEC PE=1 SV=3 4.53 2047.9 - 412200 - - - -4.3982 - 1.222 0.203 - 128.6 1 2 0 -0.0045 9 0 0 0 6.63E+07 3.35E+07 - - - 1.119 0.99 221125_WJC_METTL3_EV_vs_WT_F02.07509.07509.2 0.788 12-Jun R.IFVNDDR.H "sp|Q12906|ILF3_HUMAN,tr|K7EM82|K7EM82_HUMAN,tr|K7ER69|K7ER69_HUMAN,tr|K7ENK6|K7ENK6_HUMAN,tr|K7EJ09|K7EJ09_HUMAN,tr|K7ERM6|K7ERM6_HUMAN,tr|K7EKJ9|K7EKJ9_HUMAN" 7 877.4294 0.98 10588 7509 2 877.427284 439.722 Interleukin enhancer-binding factor 3 OS=Homo sapiens OX=9606 GN=ILF3 PE=1 SV=3 4.21 2048.6 - 1.47E+06 - - - -2.3899 - 1.374 0.177 - 127.8 1 2 0 -0.0021 7 0 0 0 1.31E+08 1.33E+08 - - - 1.3544 0.9828 221125_WJC_METTL3_EV_vs_WT_F02.07513.07513.2 0.369 12-Jun R.IFVNDDR[166.11].H "sp|Q12906|ILF3_HUMAN,tr|K7EM82|K7EM82_HUMAN,tr|K7ER69|K7ER69_HUMAN,tr|K7ENK6|K7ENK6_HUMAN,tr|K7EJ09|K7EJ09_HUMAN,tr|K7ERM6|K7ERM6_HUMAN,tr|K7EKJ9|K7EKJ9_HUMAN" 7 887.4377 1.25 10590 7513 2 887.435069 444.7261 Interleukin enhancer-binding factor 3 OS=Homo sapiens OX=9606 GN=ILF3 PE=1 SV=3 4.21 2049.1 - 1.28E+06 - - - -2.9095 - 1.283 0.19 - 142.6 1 2 0 -0.0026 7 0 0 0 1.01E+08 8.10E+07 - - - 1.2331 0.9676 221125_WJC_METTL3_EV_vs_WT_F02.07525.07525.2 3.35 12-Jun K.IMAQIER[166.11].G "sp|O60264|SMCA5_HUMAN,sp|P28370|SMCA1_HUMAN,tr|A0A0A0MRP6|A0A0A0MRP6_HUMAN,tr|B7ZLQ5|B7ZLQ5_HUMAN" 4 869.4668 0.86 10594 7525 2 869.466152 435.7407 SWI\SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A member 5 OS=Homo sapiens OX=9606 GN=SMARCA5 PE=1 SV=1 6 2050.9 - 252862 - - - -0.7947 - 1.102 0.076 - 102.2 1 2 0 -0.0007 7 0 0 0 8.94E+07 1.03E+08 - - - -0.0901 0.9912 221125_WJC_METTL3_EV_vs_WT_F02.07529.07529.2 0.302 12-Jul R.AALLTER.T "sp|Q9Y5B9|SP16H_HUMAN,sp|Q9BW19|KIFC1_HUMAN" 2 772.4443 0.93 10595 7529 2 772.44299 387.2294 FACT complex subunit SPT16 OS=Homo sapiens OX=9606 GN=SUPT16H PE=1 SV=1 6.05 2051.4 - 1.08E+06 - - - -1.6998 - 1.627 0.088 - 149.2 2 2 0 -0.0013 7 0 0 0 2.87E+08 3.09E+08 - - - 1.0983 0.9882 221125_WJC_METTL3_EV_vs_WT_F02.07542.07542.2 0.63 12-Jul K.IMAQIER.G "sp|O60264|SMCA5_HUMAN,sp|P28370|SMCA1_HUMAN,tr|A0A0A0MRP6|A0A0A0MRP6_HUMAN,tr|B7ZLQ5|B7ZLQ5_HUMAN" 4 859.4586 0.86 10598 7542 2 859.456291 430.7366 SWI\SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A member 5 OS=Homo sapiens OX=9606 GN=SMARCA5 PE=1 SV=1 6 2053.3 - 663173 - - - -2.6552 - 1.312 0.2 - 182.9 1 2 0 -0.0023 7 0 0 0 8.90E+07 1.04E+08 - - - 1.3779 0.9758 221125_WJC_METTL3_EV_vs_WT_F02.07548.07548.2 4.87 12-Jun K.LDDLVSK[136.11].S "sp|O15498|YKT6_HUMAN,tr|A0A7I2V4L6|A0A7I2V4L6_HUMAN" 2 796.4422 1.12 10600 7548 2 796.44062 399.2284 Synaptobrevin homolog YKT6 OS=Homo sapiens OX=9606 GN=YKT6 PE=1 SV=1 4.21 2054.1 - 399370 - - - -1.9637 - 1.167 0.152 - 76.3 2 2 0 -0.0016 7 0 0 0 3.99E+07 3.57E+07 - - - 0.5181 0.9971 221125_WJC_METTL3_EV_vs_WT_F02.07553.07553.2 0.183 12-Jul R.AALLTER[166.11].T "sp|Q9Y5B9|SP16H_HUMAN,sp|Q9BW19|KIFC1_HUMAN" 2 782.4526 0.93 10601 7553 2 782.450249 392.2336 FACT complex subunit SPT16 OS=Homo sapiens OX=9606 GN=SUPT16H PE=1 SV=1 6.05 2054.8 - 4.88E+06 - - - -2.9701 - 1.7 0.273 - 206.3 1 2 0 -0.0023 7 0 0 0 2.89E+08 3.09E+08 - - - 2.738 0.9747 221125_WJC_METTL3_EV_vs_WT_F02.07554.07554.2 0.000591 16-Jun K.YMHSGPVVA.M "sp|P15531|NDKA_HUMAN,tr|Q32Q12|Q32Q12_HUMAN,tr|J3KPD9|J3KPD9_HUMAN,tr|E5RHP0|E5RHP0_HUMAN,tr|E7ERL0|E7ERL0_HUMAN" 5 959.4535 - 10602 7554 2 959.45209 480.734 Nucleoside diphosphate kinase A OS=Homo sapiens OX=9606 GN=NME1 PE=1 SV=1 6.74 2055 - 486940 - - - -1.4571 - 1.485 0.467 - 83.7 1 1 0 -0.0014 9 0 0 0 - - - - - 3.6338 0.7645 221125_WJC_METTL3_EV_vs_WT_F02.07569.07569.2 4.98 14-Jun R.LLLNNGAK.M "sp|P15121|ALDR_HUMAN,tr|E9PCX2|E9PCX2_HUMAN,tr|E9PEF9|E9PEF9_HUMAN" 3 841.5022 1.68 10606 7569 2 841.500262 421.7584 Aldo-keto reductase family 1 member B1 OS=Homo sapiens OX=9606 GN=AKR1B1 PE=1 SV=3 8.75 2057.1 - 493960 - - - -2.246 - 1.062 0.02 - 48.2 5 2 0 -0.0019 8 0 0 0 1.82E+08 1.09E+08 - - - -0.9427 0.9979 221125_WJC_METTL3_EV_vs_WT_F02.07574.07574.2 0.00591 20-Jun R.VEIIANDQGNR[166.11].L "sp|P11021|BIP_HUMAN,sp|P48741|HSP77_HUMAN,sp|P54652|HSP72_HUMAN,sp|P0DMV8|HS71A_HUMAN,sp|P34931|HS71L_HUMAN,sp|P11142|HSP7C_HUMAN,sp|P0DMV9|HS71B_HUMAN,sp|P17066|HSP76_HUMAN,tr|E9PQQ4|E9PQQ4_HUMAN,tr|E9PNE6|E9PNE6_HUMAN,tr|E9PKE3|E9PKE3_HUMAN,tr|A0A7P0TB36|A0A7P0TB36_HUMAN,tr|E9PLF4|E9PLF4_HUMAN,tr|A0A7P0TAI0|A0A7P0TAI0_HUMAN,tr|Q53FA3|Q53FA3_HUMAN,tr|E9PI65|E9PI65_HUMAN,tr|E9PK54|E9PK54_HUMAN,tr|E9PN25|E9PN25_HUMAN,tr|E9PPY6|E9PPY6_HUMAN,tr|E9PQK7|E9PQK7_HUMAN,tr|A0A0G2JIW1|A0A0G2JIW1_HUMAN" 21 1237.629 0.09 10608 7574 2 1237.626254 619.8218 Endoplasmic reticulum chaperone BiP OS=Homo sapiens OX=9606 GN=HSPA5 PE=1 SV=2 4.37 2057.8 - 190820 - - - -2.2462 - 1.466 0.336 - 117 1 2 0 -0.0028 11 0 0 0 2.01E+06 2.33E+07 - - - 2.5567 0.9882 221125_WJC_METTL3_EV_vs_WT_F02.07578.07578.2 4.77 12-Aug K.IVSITER[166.11].A "sp|Q96KR1|ZFR_HUMAN,sp|Q9BVJ7|DUS23_HUMAN,tr|H0Y8W1|H0Y8W1_HUMAN" 3 826.4788 1.3 10609 7578 2 826.477694 414.2467 Zinc finger RNA-binding protein OS=Homo sapiens OX=9606 GN=ZFR PE=1 SV=2 6 2058.4 - 3.66E+06 - - - -1.3237 - 1.453 0.069 - 181.4 1 2 0 -0.0011 7 0 0 0 2.49E+08 1.92E+08 - - - 0.7342 0.9757 221125_WJC_METTL3_EV_vs_WT_F02.07580.07580.2 5.42 12-Jul K.IVSITER.A "sp|Q96KR1|ZFR_HUMAN,sp|Q9BVJ7|DUS23_HUMAN,tr|H0Y8W1|H0Y8W1_HUMAN" 3 816.4705 1.15 10610 7580 2 816.47036 409.2425 Zinc finger RNA-binding protein OS=Homo sapiens OX=9606 GN=ZFR PE=1 SV=2 6 2058.6 - 4.47E+06 - - - -0.1935 - 1.247 0.039 - 170.6 1 2 0 -0.0002 7 0 0 0 2.21E+08 1.92E+08 - - - 0.0284 0.9951 221125_WJC_METTL3_EV_vs_WT_F02.07584.07584.2 0.472 14-Aug K.FADGEVVR[166.11].G "sp|Q14739|LBR_HUMAN,tr|A0A494C1L1|A0A494C1L1_HUMAN,tr|C9JES9|C9JES9_HUMAN,tr|C9JXK0|C9JXK0_HUMAN" 4 901.4533 1.14 10612 7584 2 901.45229 451.7339 Delta(14)-sterol reductase LBR OS=Homo sapiens OX=9606 GN=LBR PE=1 SV=2 4.37 2059.1 - 2.44E+06 - - - -1.1215 - 1.445 0.153 - 150.9 1 2 0 -0.001 8 0 0 0 1.15E+08 1.01E+08 - - - 1.2809 0.9796 221125_WJC_METTL3_EV_vs_WT_F02.07590.07590.2 0.00107 18-Aug D.PATATSVDLR[166.11].D sp|P50991|TCPD_HUMAN 1 1039.5537 0.15 10615 7590 2 1039.553945 520.7841 T-complex protein 1 subunit delta OS=Homo sapiens OX=9606 GN=CCT4 PE=1 SV=4 6.27 2059.8 - 116912 - - - 0.1934 - 1.692 0.396 - 155.1 1 1 0 0.0002 10 0 0 0 7.82E+05 5.33E+06 - - - 3.4338 0.9907 221125_WJC_METTL3_EV_vs_WT_F02.07596.07596.2 0.544 16-Jul R.IIPGGVAER[166.11].H "sp|O14910|LIN7A_HUMAN,tr|H0YIA8|H0YIA8_HUMAN,tr|H0YI92|H0YI92_HUMAN" 3 920.5319 0.12 10617 7596 2 920.530213 461.2732 Protein lin-7 homolog A OS=Homo sapiens OX=9606 GN=LIN7A PE=1 SV=2 6 2060.6 - 459987 - - - -1.8174 - 1.359 0.208 - 160.2 6 2 0 -0.0017 9 0 0 0 2.41E+07 1.97E+08 - - - 1.1166 0.9619 221125_WJC_METTL3_EV_vs_WT_F02.07622.07622.2 0.942 14-Aug K.FADGEVVR.G "sp|Q14739|LBR_HUMAN,tr|A0A494C1L1|A0A494C1L1_HUMAN,tr|C9JES9|C9JES9_HUMAN,tr|C9JXK0|C9JXK0_HUMAN" 4 891.445 1.15 10623 7622 2 891.440499 446.7298 Delta(14)-sterol reductase LBR OS=Homo sapiens OX=9606 GN=LBR PE=1 SV=2 4.37 2064.6 - 1.11E+06 - - - -5.0839 - 1.329 0.26 - 170.2 1 2 0 -0.0045 8 0 0 0 1.17E+08 1.01E+08 - - - 1.8178 0.9992 221125_WJC_METTL3_EV_vs_WT_F02.07626.07626.2 0.0268 14-Oct R.LAAELEDR.R "sp|Q9NQG5|RPR1B_HUMAN,tr|A2A2M0|A2A2M0_HUMAN,tr|A0A087X2D2|A0A087X2D2_HUMAN" 3 915.4662 2.43 10625 7626 2 915.465209 458.7404 Regulation of nuclear pre-mRNA domain-containing protein 1B OS=Homo sapiens OX=9606 GN=RPRD1B PE=1 SV=1 4.14 2065 - 2.02E+06 - - - -1.0399 - 1.853 0.256 - 403.2 1 2 0 -0.001 8 0 0 0 1.06E+08 4.37E+07 - - - 2.7918 0.9938 221125_WJC_METTL3_EV_vs_WT_F02.07678.07678.2 0.142 14-Sep K.IMEVTAER[166.11].L "sp|P15735|PHKG2_HUMAN,tr|H3BN16|H3BN16_HUMAN,tr|J3KNN3|J3KNN3_HUMAN,tr|H3BTW6|H3BTW6_HUMAN,tr|H3BP07|H3BP07_HUMAN" 5 957.4829 0.75 10649 7678 2 957.485609 479.7487 "Phosphorylase b kinase gamma catalytic chain, liver\testis isoform OS=Homo sapiens OX=9606 GN=PHKG2 PE=1 SV=1" 4.53 2071.6 - 748618 - - - 2.8429 - 1.44 0.254 - 253.5 1 2 0 0.0027 8 0 0 0 2.09E+07 2.80E+07 - - - 2.0159 0.999 221125_WJC_METTL3_EV_vs_WT_F02.07703.07703.2 0.0204 12-Jul K.TPPVVIK[136.11].S sp|Q96A49|SYAP1_HUMAN 1 760.4938 0.001 10656 7703 2 760.493682 381.2542 Synapse-associated protein 1 OS=Homo sapiens OX=9606 GN=SYAP1 PE=1 SV=1 8.41 2075.1 - 2.02E+06 - - - -0.1894 - 1.268 0.344 - 180.4 1 2 0 -0.0001 7 0 0 0 0.00E+00 1.16E+09 - - - 2.3341 0.9969 221125_WJC_METTL3_EV_vs_WT_F02.07720.07720.2 0.000253 12-Aug K.YVDMSVK[136.11].T sp|P48047|ATPO_HUMAN 1 848.4193 0.79 10662 7720 2 848.42012 425.2169 "ATP synthase subunit O, mitochondrial OS=Homo sapiens OX=9606 GN=ATP5PO PE=1 SV=1" 5.83 2077.5 - 2.55E+06 - - - 0.9194 - 1.598 0.152 - 181 1 2 0 0.0008 7 0 0 0 2.06E+08 2.62E+08 - - - 1.6487 0.9956 221125_WJC_METTL3_EV_vs_WT_F02.07721.07721.2 0.000497 12-Aug K.YVDMSVK.T sp|P48047|ATPO_HUMAN 1 840.4051 0.79 10663 7721 2 840.40576 421.2098 "ATP synthase subunit O, mitochondrial OS=Homo sapiens OX=9606 GN=ATP5PO PE=1 SV=1" 5.83 2077.6 - 1.64E+06 - - - 0.7377 - 1.385 0.168 - 187.6 1 2 0 0.0006 7 0 0 0 2.06E+08 2.62E+08 - - - 1.3137 0.9865 221125_WJC_METTL3_EV_vs_WT_F02.07738.07738.2 0.77 12-Jun K.IPDEELR.Q "sp|Q99961|SH3G1_HUMAN,sp|Q99962|SH3G2_HUMAN" 2 870.4447 1.9 10670 7738 2 870.444396 436.2296 Endophilin-A2 OS=Homo sapiens OX=9606 GN=SH3GL1 PE=1 SV=1 4.14 2079.9 - 5.24E+06 - - - -0.3458 - 1.044 0.168 - 137.7 1 2 0 -0.0003 7 0 0 0 7.40E+08 3.90E+08 - - - 0.4182 0.9949 221125_WJC_METTL3_EV_vs_WT_F02.07755.07755.2 0.212 12-May K.IPDEELR[166.11].Q "sp|Q99961|SH3G1_HUMAN,sp|Q99962|SH3G2_HUMAN" 2 880.453 1.94 10676 7755 2 880.452767 441.2338 Endophilin-A2 OS=Homo sapiens OX=9606 GN=SH3GL1 PE=1 SV=1 4.14 2082.3 - 2.77E+06 - - - -0.2272 - 1.181 0.206 - 118.2 1 2 0 -0.0002 7 0 0 0 7.73E+08 3.99E+08 - - - 1.0896 0.9451 221125_WJC_METTL3_EV_vs_WT_F02.07770.07770.2 0.835 16-May R.VMVEGVGAR[166.11].V sp|Q86YT6|MIB1_HUMAN 1 926.4883 14.31 10678 7770 2 926.489155 464.2514 E3 ubiquitin-protein ligase MIB1 OS=Homo sapiens OX=9606 GN=MIB1 PE=1 SV=1 5.97 2084.9 - 129579 - - - 0.9153 - 0.992 0.104 - 86.1 2 2 0 0.0008 9 0 0 0 4.61E+07 3.22E+06 - - - -0.3488 0.9512 221125_WJC_METTL3_EV_vs_WT_F02.07798.07798.2 7.52 12-Jul K.MIIEEAK[136.11].R "sp|P48643|TCPE_HUMAN,sp|P07942|LAMB1_HUMAN,tr|E9PCA1|E9PCA1_HUMAN,tr|A0A7I2V4J9|A0A7I2V4J9_HUMAN,tr|B7ZAR1|B7ZAR1_HUMAN,tr|G3XAI2|G3XAI2_HUMAN,tr|E7ENZ3|E7ENZ3_HUMAN,tr|A0A7I2V5X5|A0A7I2V5X5_HUMAN" 8 840.4506 0.63 10689 7798 2 840.449588 421.2326 T-complex protein 1 subunit epsilon OS=Homo sapiens OX=9606 GN=CCT5 PE=1 SV=1 4.53 2088.6 - 5.63E+06 - - - -1.2517 - 1.019 0.09 - 169.9 1 2 0 -0.0011 7 0 0 0 3.30E+08 5.22E+08 - - - -0.235 0.972 221125_WJC_METTL3_EV_vs_WT_F02.07799.07799.2 3.74 12-May K.FLPNAPK[136.11].A "sp|Q92499|DDX1_HUMAN,tr|A0A7I2V2M5|A0A7I2V2M5_HUMAN,tr|A0A087X2G1|A0A087X2G1_HUMAN,tr|A0A7I2V430|A0A7I2V430_HUMAN,tr|A0A7I2V421|A0A7I2V421_HUMAN,tr|A0A7I2V4F0|A0A7I2V4F0_HUMAN,tr|A0A7I2V5X8|A0A7I2V5X8_HUMAN,tr|A0A7I2V4J3|A0A7I2V4J3_HUMAN,tr|A0A087WZ71|A0A087WZ71_HUMAN,tr|A0A7I2YQ77|A0A7I2YQ77_HUMAN" 10 793.4578 1.38 10690 7799 2 793.457502 397.7362 ATP-dependent RNA helicase DDX1 OS=Homo sapiens OX=9606 GN=DDX1 PE=1 SV=2 8.75 2088.7 - 2.15E+06 - - - -0.3441 - 0.924 0.174 - 95.2 2 2 0 -0.0003 7 0 0 0 8.52E+08 6.16E+08 - - - -0.0588 0.9769 221125_WJC_METTL3_EV_vs_WT_F02.07809.07809.2 1.69 12-Jun K.FLPNAPK.A "sp|Q92499|DDX1_HUMAN,tr|A0A7I2V2M5|A0A7I2V2M5_HUMAN,tr|A0A087X2G1|A0A087X2G1_HUMAN,tr|A0A7I2V430|A0A7I2V430_HUMAN,tr|A0A7I2V421|A0A7I2V421_HUMAN,tr|A0A7I2V4F0|A0A7I2V4F0_HUMAN,tr|A0A7I2V5X8|A0A7I2V5X8_HUMAN,tr|A0A7I2V4J3|A0A7I2V4J3_HUMAN,tr|A0A087WZ71|A0A087WZ71_HUMAN,tr|A0A7I2YQ77|A0A7I2YQ77_HUMAN" 10 785.4436 1.39 10693 7809 2 785.442485 393.7291 ATP-dependent RNA helicase DDX1 OS=Homo sapiens OX=9606 GN=DDX1 PE=1 SV=2 8.75 2090.1 - 4.47E+06 - - - -1.3878 - 0.959 0.189 - 134.2 1 2 0 -0.0011 7 0 0 0 8.54E+08 6.16E+08 - - - 0.304 0.9881 221125_WJC_METTL3_EV_vs_WT_F02.07827.07827.2 5.16 12-Jun K.MIIEEAK.R "sp|P48643|TCPE_HUMAN,sp|P07942|LAMB1_HUMAN,tr|E9PCA1|E9PCA1_HUMAN,tr|A0A7I2V4J9|A0A7I2V4J9_HUMAN,tr|B7ZAR1|B7ZAR1_HUMAN,tr|G3XAI2|G3XAI2_HUMAN,tr|E7ENZ3|E7ENZ3_HUMAN,tr|A0A7I2V5X5|A0A7I2V5X5_HUMAN" 8 832.4364 0.63 10698 7827 2 832.436411 417.2255 T-complex protein 1 subunit epsilon OS=Homo sapiens OX=9606 GN=CCT5 PE=1 SV=1 4.53 2092.7 - 6.70E+06 - - - -0.036 - 1.136 0.143 - 154.2 1 2 0 0 7 0 0 0 3.30E+08 5.22E+08 - - - 0.5012 0.9957 221125_WJC_METTL3_EV_vs_WT_F02.07839.07839.2 0.174 12-Jun K.ELGTVMR.M "sp|P02585|TNNC2_HUMAN,sp|P0DP25|CALM3_HUMAN,sp|P0DP23|CALM1_HUMAN,sp|P27482|CALL3_HUMAN,sp|P0DP24|CALM2_HUMAN,tr|C9J7T9|C9J7T9_HUMAN,tr|F8WBR5|F8WBR5_HUMAN,tr|G3V479|G3V479_HUMAN,tr|M0QZ52|M0QZ52_HUMAN,tr|E7EMB3|E7EMB3_HUMAN" 10 804.4164 1.22 10701 7839 2 804.416439 403.2155 "Troponin C, skeletal muscle OS=Homo sapiens OX=9606 GN=TNNC2 PE=1 SV=2" 6.1 2094.6 - 1.05E+07 - - - 0.0808 - 1.255 0.196 - 238.6 1 2 0 0.0001 7 0 0 0 4.75E+08 3.89E+08 - - - 1.2083 0.9849 221125_WJC_METTL3_EV_vs_WT_F02.07855.07855.2 0.986 12-Jun K.FIEEQVR.R sp|O60870|KIN17_HUMAN 1 919.4763 0.87 10705 7855 2 919.476702 460.7454 DNA\RNA-binding protein KIN17 OS=Homo sapiens OX=9606 GN=KIN PE=1 SV=2 4.53 2096.9 - 708672 - - - 0.4035 - 1.076 0.15 - 156.3 1 2 0 0.0004 7 0 0 0 3.63E+07 4.19E+07 - - - 0.3809 0.9989 221125_WJC_METTL3_EV_vs_WT_F02.07861.07861.2 0.217 14-Sep R.LVNELTEK.T sp|Q86UP2|KTN1_HUMAN 1 944.5179 2.21 10707 7861 2 944.517686 473.2662 Kinectin OS=Homo sapiens OX=9606 GN=KTN1 PE=1 SV=1 4.53 2097.8 - 834374 - - - -0.1863 - 1.412 0.303 - 187.2 1 2 0 -0.0002 8 0 0 0 5.85E+07 2.65E+07 - - - 2.3194 0.9739 221125_WJC_METTL3_EV_vs_WT_F02.07868.07868.2 0.19 14-Jul K.VIVAVGDR[166.11].S sp|Q8TEM1|PO210_HUMAN 1 837.4948 1.76 10709 7868 2 837.495831 419.7547 Nuclear pore membrane glycoprotein 210 OS=Homo sapiens OX=9606 GN=NUP210 PE=1 SV=3 5.81 2098.8 - 3.91E+06 - - - 1.2645 - 1.257 0.07 - 140.5 1 2 0 0.0011 8 0 0 0 6.07E+08 3.44E+08 - - - 0.2475 0.9971 221125_WJC_METTL3_EV_vs_WT_F02.07871.07871.2 0.287 12-Jun R.VIIYQEK.Q "sp|Q9UHX1|PUF60_HUMAN,tr|A0A0J9YYL3|A0A0J9YYL3_HUMAN,tr|A0A0J9YXX5|A0A0J9YXX5_HUMAN,tr|A0A0J9YXJ8|A0A0J9YXJ8_HUMAN,tr|A0A0J9YVP6|A0A0J9YVP6_HUMAN" 5 891.5066 1.05 10710 7871 2 891.505987 446.7606 Poly(U)-binding-splicing factor PUF60 OS=Homo sapiens OX=9606 GN=PUF60 PE=1 SV=1 5.97 2099.1 - 680712 - - - -0.6528 - 1.193 0.263 - 128.7 1 2 0 -0.0006 7 0 0 0 2.04E+08 1.94E+08 - - - 1.5425 0.9853 221125_WJC_METTL3_EV_vs_WT_F02.07873.07873.2 0.63 14-May K.TIADAEER[166.11].K "sp|Q96DT5|DYH11_HUMAN,tr|A0A087WYC6|A0A087WYC6_HUMAN,tr|A0A0C4DFR0|A0A0C4DFR0_HUMAN" 3 913.438 2.18 10711 7873 2 913.437644 457.7263 Dynein axonemal heavy chain 11 OS=Homo sapiens OX=9606 GN=DNAH11 PE=1 SV=4 4.14 2099.4 - 139147 - - - -0.439 - 1.008 0.177 - 120.8 1 2 0 -0.0004 8 0 0 0 3.90E+07 1.79E+07 - - - 0.3722 0.9994 221125_WJC_METTL3_EV_vs_WT_F02.07880.07880.2 0.00216 14-Jul R.VAMIDETR.N "sp|Q16891|MIC60_HUMAN,tr|B9A067|B9A067_HUMAN,tr|A0A087WYS0|A0A087WYS0_HUMAN,tr|C9J406|C9J406_HUMAN,tr|H7C463|H7C463_HUMAN" 5 933.459 1.32 10713 7880 2 933.460562 467.7368 MICOS complex subunit MIC60 OS=Homo sapiens OX=9606 GN=IMMT PE=1 SV=1 4.37 2100.4 - 199793 - - - 1.7087 - 1.778 0.369 - 216.3 1 2 0 0.0016 8 0 0 0 2.33E+07 1.77E+07 - - - 3.5016 0.9925 221125_WJC_METTL3_EV_vs_WT_F02.07888.07888.2 0.405 12-Jul K.TVYPMER[166.11].L "sp|Q9BT23|LIMD2_HUMAN,sp|Q9UHB6|LIMA1_HUMAN,tr|J3QQM5|J3QQM5_HUMAN,tr|F8VQE1|F8VQE1_HUMAN,tr|F8VS07|F8VS07_HUMAN" 5 904.4352 0.57 10716 7888 2 904.433816 453.2249 LIM domain-containing protein 2 OS=Homo sapiens OX=9606 GN=LIMD2 PE=1 SV=1 5.66 2101.5 - 848012 - - - -1.5391 - 1.09 0.248 - 231.9 1 2 0 -0.0014 7 0 0 0 2.29E+07 4.02E+07 - - - 1.1453 0.9682 221125_WJC_METTL3_EV_vs_WT_F02.07889.07889.2 1.99 14-Jul R.AIPGVVEK.V sp|P42285|MTREX_HUMAN 1 811.4804 1.08 10717 7889 2 811.480407 406.7475 Exosome RNA helicase MTR4 OS=Homo sapiens OX=9606 GN=MTREX PE=1 SV=3 6.05 2101.6 - 774010 - - - 0.0653 - 1.062 0.086 - 128.7 1 2 0 0.0001 8 0 0 0 4.17E+07 3.85E+07 - - - -0.1424 0.8506 221125_WJC_METTL3_EV_vs_WT_F02.07893.07893.2 1.37 12-Jul D.ILQSLEK.Y "sp|Q92611|EDEM1_HUMAN,sp|P49790|NU153_HUMAN" 2 829.4909 1.06 10719 7893 2 829.490537 415.7527 ER degradation-enhancing alpha-mannosidase-like protein 1 OS=Homo sapiens OX=9606 GN=EDEM1 PE=1 SV=1 6 2102 - 7.30E+06 - - - -0.4605 - 1.539 0.15 - 114.7 1 1 0 -0.0004 7 0 0 0 3.61E+08 3.41E+08 - - - 1.5148 0.9989 221125_WJC_METTL3_EV_vs_WT_F02.07905.07905.2 0.184 18-Oct K.FGAVEGAVAK.Y "sp|Q9H7Z7|PGES2_HUMAN,tr|A0A7I2V5T7|A0A7I2V5T7_HUMAN,tr|A6NHH0|A6NHH0_HUMAN,tr|X6RJ95|X6RJ95_HUMAN,tr|A0A7I2V5X6|A0A7I2V5X6_HUMAN" 5 947.5076 1.19 10723 7905 2 947.50743 474.7611 Prostaglandin E synthase 2 OS=Homo sapiens OX=9606 GN=PTGES2 PE=1 SV=1 6 2103.6 - 916925 - - - -0.2132 - 1.74 0.231 - 297.3 1 2 0 -0.0002 10 0 0 0 2.93E+07 2.47E+07 - - - 2.2932 0.9958 221125_WJC_METTL3_EV_vs_WT_F02.07909.07909.2 0.0095 16-Jul R.LIPDGC[160.03]GVK[136.11].Y "sp|P27635|RL10_HUMAN,sp|Q96L21|RL10L_HUMAN,tr|F8W7C6|F8W7C6_HUMAN,tr|X1WI28|X1WI28_HUMAN" 4 965.5096 0.94 10725 7909 2 965.509953 483.7621 60S ribosomal protein L10 OS=Homo sapiens OX=9606 GN=RPL10 PE=1 SV=4 5.83 2104.2 - 375499 - - - 0.4143 - 1.444 0.176 - 170.8 2 2 0 0.0004 9 0 0 0 3.18E+08 3.38E+08 - - - 1.2693 0.9965 221125_WJC_METTL3_EV_vs_WT_F02.07916.07916.2 0.24 12-Jun K.VEAILEK[136.11].V sp|O95817|BAG3_HUMAN 1 808.4786 0.74 10726 7916 2 808.478427 405.2466 BAG family molecular chaperone regulator 3 OS=Homo sapiens OX=9606 GN=BAG3 PE=1 SV=3 4.53 2105.4 - 1.82E+06 - - - -0.1769 - 1.51 0.138 - 110.7 1 2 0 -0.0001 7 0 0 0 5.45E+07 7.40E+07 - - - 1.366 0.9981 221125_WJC_METTL3_EV_vs_WT_F02.07917.07917.2 0.349 16-Oct R.LGPAGASLR[166.11].R "sp|Q8IXZ3|SP8_HUMAN,sp|P0CG40|SP9_HUMAN,tr|A0A087X0Q6|A0A087X0Q6_HUMAN" 3 850.49 0.46 10727 7917 2 850.49023 426.2523 Transcription factor Sp8 OS=Homo sapiens OX=9606 GN=SP8 PE=1 SV=3 9.75 2105.5 - 975693 - - - 0.2457 - 1.892 0.129 - 377.7 1 2 0 0.0002 9 0 0 0 1.20E+08 2.60E+08 - - - 1.8384 0.9676 221125_WJC_METTL3_EV_vs_WT_F02.07920.07920.2 3.95 16-Jun R.VVAVSPQMR[166.11].L "sp|Q9Y4A5|TRRAP_HUMAN,tr|A0A2R8YFJ4|A0A2R8YFJ4_HUMAN,tr|H0Y4W2|H0Y4W2_HUMAN,tr|F2Z2U4|F2Z2U4_HUMAN" 4 995.5462 0.92 10728 7920 2 995.547143 498.7804 Transformation\transcription domain-associated protein OS=Homo sapiens OX=9606 GN=TRRAP PE=1 SV=3 9.72 2105.9 - 184416 - - - 0.9914 - 1.182 0.067 - 94.3 1 2 0 0.001 9 0 0 0 1.19E+07 1.30E+07 - - - 0.0193 0.996 221125_WJC_METTL3_EV_vs_WT_F02.07923.07923.2 1.05 12-Jul K.SLLVQTK.R "sp|P39023|RL3_HUMAN,tr|G5E9G0|G5E9G0_HUMAN" 2 787.4804 0.63 10729 7923 2 787.480634 394.7475 60S ribosomal protein L3 OS=Homo sapiens OX=9606 GN=RPL3 PE=1 SV=2 8.47 2106.3 - 2.12E+06 - - - 0.3556 - 1.453 0.145 - 189.9 1 2 0 0.0003 7 0 0 0 7.68E+07 1.21E+08 - - - 1.2958 0.9306 221125_WJC_METTL3_EV_vs_WT_F02.07932.07932.2 0.673 14-Jun K.APDGYIVK.S "sp|Q92499|DDX1_HUMAN,tr|A0A7I2V2M5|A0A7I2V2M5_HUMAN,tr|A0A087X2G1|A0A087X2G1_HUMAN,tr|A0A7I2V430|A0A7I2V430_HUMAN,tr|A0A7I2V421|A0A7I2V421_HUMAN,tr|A0A7I2V4F0|A0A7I2V4F0_HUMAN,tr|A0A7I2V5X8|A0A7I2V5X8_HUMAN,tr|A0A7I2V4J3|A0A7I2V4J3_HUMAN,tr|A0A087WZ71|A0A087WZ71_HUMAN,tr|A0A7I2YQ77|A0A7I2YQ77_HUMAN" 10 861.4596 1.03 10732 7932 2 861.46128 431.7371 ATP-dependent RNA helicase DDX1 OS=Homo sapiens OX=9606 GN=DDX1 PE=1 SV=2 5.88 2107.7 - 241157 - - - 1.9281 - 1.087 0.129 - 76.7 8 2 0 0.0017 8 0 0 0 1.71E+08 1.65E+08 - - - -0.1585 0.9771 221125_WJC_METTL3_EV_vs_WT_F02.07933.07933.2 2.54 16-Jun R.VVAVSPQMR.L "sp|Q9Y4A5|TRRAP_HUMAN,tr|A0A2R8YFJ4|A0A2R8YFJ4_HUMAN,tr|H0Y4W2|H0Y4W2_HUMAN,tr|F2Z2U4|F2Z2U4_HUMAN" 4 985.5379 0.92 10733 7933 2 985.538162 493.7762 Transformation\transcription domain-associated protein OS=Homo sapiens OX=9606 GN=TRRAP PE=1 SV=3 9.72 2107.8 - 180990 - - - 0.2801 - 1.034 0.129 - 139 1 2 0 0.0003 9 0 0 0 1.19E+07 1.29E+07 - - - 0.0904 0.8767 221125_WJC_METTL3_EV_vs_WT_F02.07934.07934.2 6.36 12-Jul K.ELLTLIR.S "sp|Q15067|ACOX1_HUMAN,sp|Q92620|PRP16_HUMAN,tr|K7ENF1|K7ENF1_HUMAN,tr|K7ESC7|K7ESC7_HUMAN" 4 856.5382 1426.42 10734 7934 2 856.537132 429.2764 Peroxisomal acyl-coenzyme A oxidase 1 OS=Homo sapiens OX=9606 GN=ACOX1 PE=1 SV=3 6.1 2107.9 - 470518 - - - -1.2504 - 1.075 0.001 - 111.9 2 2 0 -0.0011 7 0 0 0 8.29E+08 5.81E+05 - - - -0.8573 0.998 221125_WJC_METTL3_EV_vs_WT_F02.07938.07938.2 1.05 16-Oct R.LGPAGASLR.R "sp|Q8IXZ3|SP8_HUMAN,sp|P0CG40|SP9_HUMAN,tr|A0A087X0Q6|A0A087X0Q6_HUMAN" 3 840.4818 0.46 10735 7938 2 840.482339 421.2482 Transcription factor Sp8 OS=Homo sapiens OX=9606 GN=SP8 PE=1 SV=3 9.75 2108.6 - 2.34E+06 - - - 0.6996 - 1.756 0.169 - 258.1 1 2 0 0.0006 9 0 0 0 8.42E+07 1.82E+08 - - - 1.918 0.9766 221125_WJC_METTL3_EV_vs_WT_F02.07939.07939.2 2.35 12-Aug K.ISAIIEK[136.11].R "sp|Q13123|RED_HUMAN,sp|Q8TDW7|FAT3_HUMAN,tr|E9PQ73|E9PQ73_HUMAN,tr|G5EA25|G5EA25_HUMAN" 4 780.4837 0.88 10736 7939 2 780.484977 391.2491 Protein Red OS=Homo sapiens OX=9606 GN=IK PE=1 SV=3 6 2108.7 - 549373 - - - 1.6938 - 1.41 0.076 - 129.5 3 2 0 0.0013 7 0 0 0 2.19E+08 2.49E+08 - - - 0.4775 0.9989 221125_WJC_METTL3_EV_vs_WT_F02.07942.07942.2 0.00636 14-Aug K.EVVAEVVK[136.11].A sp|O60832|DKC1_HUMAN 1 879.5157 0.56 10737 7942 2 879.516353 440.7651 H\ACA ribonucleoprotein complex subunit DKC1 OS=Homo sapiens OX=9606 GN=DKC1 PE=1 SV=3 4.53 2109.1 - 1.17E+06 - - - 0.7606 - 1.591 0.275 - 257.1 1 2 0 0.0007 8 0 0 0 3.57E+07 6.43E+07 - - - 2.4724 0.9994 221125_WJC_METTL3_EV_vs_WT_F02.07943.07943.2 0.00123 20-Aug R.ISSVLAGGSC[160.03]R.A "sp|P02533|K1C14_HUMAN,sp|P08779|K1C16_HUMAN,tr|K7ENV3|K7ENV3_HUMAN" 3 1105.555 387.2 10738 7943 2 1105.556129 553.7848 "Keratin, type I cytoskeletal 14 OS=Homo sapiens OX=9606 GN=KRT14 PE=1 SV=4" 8.25 2109.2 - 220657 - - - 1.0275 - 1.748 0.343 - 120.6 1 2 0 0.0011 11 0 0 0 8.67E+06 2.24E+04 - - - 3.0848 0.9911 221125_WJC_METTL3_EV_vs_WT_F02.07949.07949.2 1.06 12-Sep K.ISAIIEK.R "sp|Q13123|RED_HUMAN,sp|Q8TDW7|FAT3_HUMAN,tr|E9PQ73|E9PQ73_HUMAN,tr|G5EA25|G5EA25_HUMAN" 4 772.4695 0.88 10742 7949 2 772.470254 387.242 Protein Red OS=Homo sapiens OX=9606 GN=IK PE=1 SV=3 6 2110 - 876488 - - - 1.0343 - 1.495 0.079 - 202.9 1 2 0 0.0008 7 0 0 0 2.19E+08 2.49E+08 - - - 0.8984 0.9806 221125_WJC_METTL3_EV_vs_WT_F02.07973.07973.2 2.29 12-May K.IPDEELR[166.11].Q "sp|Q99961|SH3G1_HUMAN,sp|Q99962|SH3G2_HUMAN" 2 880.453 2.08 10752 7973 2 880.453451 441.2338 Endophilin-A2 OS=Homo sapiens OX=9606 GN=SH3GL1 PE=1 SV=1 4.14 2113.3 - 345300 - - - 0.5497 - 1.18 0.092 - 78 1 2 0 0.0005 7 0 0 0 8.38E+08 4.02E+08 - - - 0.2448 0.9849 221125_WJC_METTL3_EV_vs_WT_F02.07995.07995.2 0.494 16-May K.DVDAAYMNK.V "sp|P48668|K2C6C_HUMAN,sp|P04259|K2C6B_HUMAN,sp|P13647|K2C5_HUMAN,sp|Q14CN4|K2C72_HUMAN,sp|O95678|K2C75_HUMAN,sp|P02538|K2C6A_HUMAN,tr|F8W0C6|F8W0C6_HUMAN,tr|H0YIN9|H0YIN9_HUMAN" 8 1025.4488 191.89 10760 7995 2 1025.448788 513.7317 "Keratin, type II cytoskeletal 6C OS=Homo sapiens OX=9606 GN=KRT6C PE=1 SV=3" 4.21 2116.5 - 158832 - - - -0.0078 - 0.82 0.254 - 57.1 1 2 0 0 9 0 0 0 1.11E+07 5.78E+04 - - - 0.3429 0.9974 221125_WJC_METTL3_EV_vs_WT_F02.08009.08009.2 0.205 14-Jun K.APDGYIVK[136.11].S "sp|Q92499|DDX1_HUMAN,tr|A0A7I2V2M5|A0A7I2V2M5_HUMAN,tr|A0A087X2G1|A0A087X2G1_HUMAN,tr|A0A7I2V430|A0A7I2V430_HUMAN,tr|A0A7I2V421|A0A7I2V421_HUMAN,tr|A0A7I2V4F0|A0A7I2V4F0_HUMAN,tr|A0A7I2V5X8|A0A7I2V5X8_HUMAN,tr|A0A7I2V4J3|A0A7I2V4J3_HUMAN,tr|A0A087WZ71|A0A087WZ71_HUMAN,tr|A0A7I2YQ77|A0A7I2YQ77_HUMAN" 10 869.4738 1.01 10765 8009 2 869.473133 435.7442 ATP-dependent RNA helicase DDX1 OS=Homo sapiens OX=9606 GN=DDX1 PE=1 SV=2 5.88 2118.4 - 1.89E+06 - - - -0.789 - 1.193 0.283 - 116.4 1 2 0 -0.0007 8 0 0 0 1.74E+08 1.72E+08 - - - 1.6633 0.8848 221125_WJC_METTL3_EV_vs_WT_F02.08022.08022.2 1.54 14-Aug K.GALALEEK.R sp|P35579|MYH9_HUMAN 1 829.4545 1.5 10769 8022 2 829.452628 415.7345 Myosin-9 OS=Homo sapiens OX=9606 GN=MYH9 PE=1 SV=4 4.53 2120.1 - 9.49E+06 - - - -2.2967 - 1.263 0 - 201.2 2 2 0 -0.0019 8 0 0 0 4.80E+08 3.21E+08 - - - -0.3899 0.9898 221125_WJC_METTL3_EV_vs_WT_F02.08033.08033.2 0.352 12-Jul R.TVEALYK.F "sp|Q00325|MPCP_HUMAN,tr|F8VVM2|F8VVM2_HUMAN" 2 822.4487 0.57 10775 8033 2 822.44745 412.2316 "Phosphate carrier protein, mitochondrial OS=Homo sapiens OX=9606 GN=SLC25A3 PE=1 SV=2" 5.66 2121.4 - 1.41E+06 - - - -1.5442 - 1.198 0.178 - 161.4 1 2 0 -0.0013 7 0 0 0 2.06E+08 3.59E+08 - - - 0.9277 0.8866 221125_WJC_METTL3_EV_vs_WT_F02.08046.08046.2 1.38 14-Sep K.GALALEEK[136.11].R sp|P35579|MYH9_HUMAN 1 837.4687 1.49 10780 8046 2 837.465775 419.7416 Myosin-9 OS=Homo sapiens OX=9606 GN=MYH9 PE=1 SV=4 4.53 2123.1 - 5.20E+06 - - - -3.5321 - 1.533 0 - 243.8 2 2 0 -0.003 8 0 0 0 4.77E+08 3.21E+08 - - - 0.1941 0.9762 221125_WJC_METTL3_EV_vs_WT_F02.08048.08048.2 1.18 12-Jul R.LEDSVLK.G sp|Q6IQ49|SDE2_HUMAN 1 802.4436 2.3 10781 8048 2 802.441165 402.2291 Replication stress response regulator SDE2 OS=Homo sapiens OX=9606 GN=SDE2 PE=1 SV=1 4.37 2123.3 - 3.82E+06 - - - -3.0769 - 1.36 0.145 - 134.3 1 2 0 -0.0025 7 0 0 0 2.07E+08 9.00E+07 - - - 1.0855 0.8378 221125_WJC_METTL3_EV_vs_WT_F02.08053.08053.2 0.201 14-Aug F.SMAGVVVR.A "sp|P52272|HNRPM_HUMAN,tr|M0R019|M0R019_HUMAN,tr|M0R0N3|M0R0N3_HUMAN,tr|A0A087X0X3|A0A087X0X3_HUMAN,tr|M0QZM1|M0QZM1_HUMAN,tr|M0QYQ7|M0QYQ7_HUMAN,tr|M0R2T0|M0R2T0_HUMAN" 7 817.448 1.28 10783 8053 2 817.446113 409.7313 Heterogeneous nuclear ribonucleoprotein M OS=Homo sapiens OX=9606 GN=HNRNPM PE=1 SV=3 9.47 2123.9 - 956511 - - - -2.3182 - 1.538 0.255 - 194.5 1 1 0 -0.0019 8 0 0 0 2.77E+08 2.16E+08 - - - 2.2222 0.9725 221125_WJC_METTL3_EV_vs_WT_F02.08058.08058.2 0.0916 14-Aug K.LTDFGAAR.E "sp|Q9UHD2|TBK1_HUMAN,sp|Q14164|IKKE_HUMAN,tr|A0A7I2V646|A0A7I2V646_HUMAN,tr|A0A7I2V4Z2|A0A7I2V4Z2_HUMAN,tr|A0A494C079|A0A494C079_HUMAN,tr|A0A494C045|A0A494C045_HUMAN,tr|A0A7I2YQG4|A0A7I2YQG4_HUMAN,tr|A0A494C1M6|A0A494C1M6_HUMAN,tr|A0A494C0A8|A0A494C0A8_HUMAN,tr|A0A494C1I2|A0A494C1I2_HUMAN,tr|A0A7I2V4W4|A0A7I2V4W4_HUMAN,tr|A0A7I2V322|A0A7I2V322_HUMAN,tr|A0A7I2V3E0|A0A7I2V3E0_HUMAN,tr|A0A7I2V463|A0A7I2V463_HUMAN,tr|A0A494C148|A0A494C148_HUMAN,tr|A0A075B7B4|A0A075B7B4_HUMAN,tr|A0A494C0X2|A0A494C0X2_HUMAN,tr|A0A7I2V615|A0A7I2V615_HUMAN,tr|A0A494C167|A0A494C167_HUMAN,tr|A0A7I2V2F4|A0A7I2V2F4_HUMAN,tr|A0A494C0R4|A0A494C0R4_HUMAN,tr|A0A7I2V643|A0A7I2V643_HUMAN,tr|A0A7I2V4Y1|A0A7I2V4Y1_HUMAN" 23 849.4345 0.29 10785 8058 2 849.431389 425.7245 Serine\threonine-protein kinase TBK1 OS=Homo sapiens OX=9606 GN=TBK1 PE=1 SV=1 5.84 2124.5 - 1.32E+06 - - - -3.6236 - 1.549 0.141 - 141.7 2 2 0 -0.0031 8 0 0 0 4.48E+07 1.53E+08 - - - 1.2668 0.9587 221125_WJC_METTL3_EV_vs_WT_F02.08070.08070.2 0.23 12-Jul R.VEEITMR[166.11].E "sp|O60216|RAD21_HUMAN,tr|E5RFV8|E5RFV8_HUMAN,tr|E5RIN7|E5RIN7_HUMAN" 3 886.4458 0.73 10788 8070 2 886.442841 444.2302 Double-strand-break repair protein rad21 homolog OS=Homo sapiens OX=9606 GN=RAD21 PE=1 SV=2 4.53 2126.2 - 698876 - - - -3.3076 - 1.254 0.142 - 203 1 2 0 -0.0029 7 0 0 0 2.35E+07 3.21E+07 - - - 0.8061 0.8079 221125_WJC_METTL3_EV_vs_WT_F02.08073.08073.2 12.2 14-Jul K.LTDFGAAR[166.11].E "sp|Q9UHD2|TBK1_HUMAN,sp|Q14164|IKKE_HUMAN,tr|A0A7I2V646|A0A7I2V646_HUMAN,tr|A0A7I2V4Z2|A0A7I2V4Z2_HUMAN,tr|A0A494C079|A0A494C079_HUMAN,tr|A0A494C045|A0A494C045_HUMAN,tr|A0A7I2YQG4|A0A7I2YQG4_HUMAN,tr|A0A494C1M6|A0A494C1M6_HUMAN,tr|A0A494C0A8|A0A494C0A8_HUMAN,tr|A0A494C1I2|A0A494C1I2_HUMAN,tr|A0A7I2V4W4|A0A7I2V4W4_HUMAN,tr|A0A7I2V322|A0A7I2V322_HUMAN,tr|A0A7I2V3E0|A0A7I2V3E0_HUMAN,tr|A0A7I2V463|A0A7I2V463_HUMAN,tr|A0A494C148|A0A494C148_HUMAN,tr|A0A075B7B4|A0A075B7B4_HUMAN,tr|A0A494C0X2|A0A494C0X2_HUMAN,tr|A0A7I2V615|A0A7I2V615_HUMAN,tr|A0A494C167|A0A494C167_HUMAN,tr|A0A7I2V2F4|A0A7I2V2F4_HUMAN,tr|A0A494C0R4|A0A494C0R4_HUMAN,tr|A0A7I2V643|A0A7I2V643_HUMAN,tr|A0A7I2V4Y1|A0A7I2V4Y1_HUMAN" 23 859.4427 0.28 10789 8073 2 859.440138 430.7286 Serine\threonine-protein kinase TBK1 OS=Homo sapiens OX=9606 GN=TBK1 PE=1 SV=1 5.84 2126.6 - 911976 - - - -3.0241 - 1.234 0.022 - 123.4 4 2 0 -0.0026 8 0 0 0 4.93E+07 1.74E+08 - - - -0.4321 0.9725 221125_WJC_METTL3_EV_vs_WT_F02.08083.08083.2 0.388 16-Aug R.VPPPPPIAR.A "sp|P07910|HNRPC_HUMAN,tr|B4DY08|B4DY08_HUMAN,tr|G3V575|G3V575_HUMAN,tr|G3V5V7|G3V5V7_HUMAN,tr|B2R5W2|B2R5W2_HUMAN,tr|G3V4C1|G3V4C1_HUMAN,tr|G3V576|G3V576_HUMAN,tr|G3V2D6|G3V2D6_HUMAN,tr|G3V4W0|G3V4W0_HUMAN,tr|G3V555|G3V555_HUMAN,tr|G3V2Q1|G3V2Q1_HUMAN" 11 942.5651 1.5 10792 8083 2 942.563335 472.2898 Heterogeneous nuclear ribonucleoproteins C1\C2 OS=Homo sapiens OX=9606 GN=HNRNPC PE=1 SV=4 9.72 2128.1 - 1.23E+06 - - - -1.8588 - 1.451 0.036 - 212.4 1 2 0 -0.0018 9 0 0 0 1.09E+09 7.29E+08 - - - 0.3833 0.9871 221125_WJC_METTL3_EV_vs_WT_F02.08086.08086.2 0.0708 16-Sep R.VPPPPPIAR[166.11].A "sp|P07910|HNRPC_HUMAN,tr|B4DY08|B4DY08_HUMAN,tr|G3V575|G3V575_HUMAN,tr|G3V5V7|G3V5V7_HUMAN,tr|B2R5W2|B2R5W2_HUMAN,tr|G3V4C1|G3V4C1_HUMAN,tr|G3V576|G3V576_HUMAN,tr|G3V2D6|G3V2D6_HUMAN,tr|G3V4W0|G3V4W0_HUMAN,tr|G3V555|G3V555_HUMAN,tr|G3V2Q1|G3V2Q1_HUMAN" 11 952.5734 1.5 10793 8086 2 952.569617 477.294 Heterogeneous nuclear ribonucleoproteins C1\C2 OS=Homo sapiens OX=9606 GN=HNRNPC PE=1 SV=4 9.72 2128.5 - 1.39E+06 - - - -3.9262 - 1.421 0.268 - 301.8 1 2 0 -0.0037 9 0 0 0 1.12E+09 7.51E+08 - - - 2.0358 0.9976 221125_WJC_METTL3_EV_vs_WT_F02.08093.08093.2 0.0194 12-Aug K.LASTPFK[136.11].G sp|P42166|LAP2A_HUMAN 1 770.4418 0.86 10796 8093 2 770.439255 386.2282 "Lamina-associated polypeptide 2, isoform alpha OS=Homo sapiens OX=9606 GN=TMPO PE=1 SV=2" 8.75 2129.3 - 2.08E+06 - - - -3.2903 - 1.738 0.324 - 164.6 1 2 0 -0.0025 7 0 0 0 1.11E+08 1.30E+08 - - - 3.1846 0.9724 221125_WJC_METTL3_EV_vs_WT_F02.08095.08095.2 3.81 12-Jun R.FLPDEAR.S "sp|O95298|NDUC2_HUMAN,sp|E9PQ53|NDUCR_HUMAN,tr|A0A087WUM3|A0A087WUM3_HUMAN,tr|A0A087WY27|A0A087WY27_HUMAN,tr|E9PRJ5|E9PRJ5_HUMAN,tr|E9PM14|E9PM14_HUMAN,tr|E9PRQ4|E9PRQ4_HUMAN" 7 846.4236 1.51 10797 8095 2 846.421537 424.2191 NADH dehydrogenase [ubiquinone] 1 subunit C2 OS=Homo sapiens OX=9606 GN=NDUFC2 PE=1 SV=1 4.37 2129.5 - 686263 - - - -2.3995 - 1.227 0.128 - 145 1 2 0 -0.002 7 0 0 0 9.21E+07 6.11E+07 - - - 0.634 0.9506 221125_WJC_METTL3_EV_vs_WT_F02.08102.08102.2 4.11 12-Jun R.FLPDEAR[166.11].S "sp|O95298|NDUC2_HUMAN,sp|E9PQ53|NDUCR_HUMAN,tr|A0A087WUM3|A0A087WUM3_HUMAN,tr|A0A087WY27|A0A087WY27_HUMAN,tr|E9PRJ5|E9PRJ5_HUMAN,tr|E9PM14|E9PM14_HUMAN,tr|E9PRQ4|E9PRQ4_HUMAN" 7 856.4318 1.51 10801 8102 2 856.428902 429.2232 NADH dehydrogenase [ubiquinone] 1 subunit C2 OS=Homo sapiens OX=9606 GN=NDUFC2 PE=1 SV=1 4.37 2130.2 - 561426 - - - -3.4282 - 1.236 0.139 - 178.1 1 2 0 -0.0029 7 0 0 0 9.21E+07 6.10E+07 - - - 0.7381 0.9989 221125_WJC_METTL3_EV_vs_WT_F02.08104.08104.2 0.125 14-Aug K.LYSESLAR.Y "sp|P31150|GDIA_HUMAN,sp|P50395|GDIB_HUMAN,tr|Q5SX91|Q5SX91_HUMAN,tr|Q5SX87|Q5SX87_HUMAN" 4 937.4869 1.41 10803 8104 2 937.485847 469.7507 Rab GDP dissociation inhibitor alpha OS=Homo sapiens OX=9606 GN=GDI1 PE=1 SV=2 6 2130.5 - 701235 - - - -1.1189 - 1.553 0.292 - 212.5 1 2 0 -0.001 8 0 0 0 1.05E+08 7.46E+07 - - - 2.525 0.9993 221125_WJC_METTL3_EV_vs_WT_F02.08110.08110.2 0.0263 12-Jul K.YGDSLYR[166.11].C "sp|Q9BZE4|GTPB4_HUMAN,tr|Q5T3R7|Q5T3R7_HUMAN" 2 882.4111 1 10805 8110 2 882.411649 442.2128 GTP-binding protein 4 OS=Homo sapiens OX=9606 GN=GTPBP4 PE=1 SV=3 5.83 2131.3 - 977673 - - - 0.6199 - 1.487 0.334 - 145.3 1 2 0 0.0005 7 0 0 0 2.16E+07 2.16E+07 - - - 2.7649 0.9584 221125_WJC_METTL3_EV_vs_WT_F02.08119.08119.2 1.96 12-Jun K.LPVDQYR[166.11].K "sp|Q629K1|TRIQK_HUMAN,tr|E5RIT1|E5RIT1_HUMAN,tr|E5RGJ1|E5RGJ1_HUMAN,tr|E5RG44|E5RG44_HUMAN" 4 899.474 42.41 10812 8119 2 899.47141 450.7443 Triple QxxK\R motif-containing protein OS=Homo sapiens OX=9606 GN=TRIQK PE=3 SV=1 5.84 2132.3 - 0 - - - -2.9206 - 1.246 0.118 - 130.1 1 2 0 -0.0026 7 0 0 0 2.98E+08 7.04E+06 - - - 0.6086 0.9401 221125_WJC_METTL3_EV_vs_WT_F02.08131.08131.2 0.12 14-Jul K.LYSESLAR[166.11].Y "sp|P31150|GDIA_HUMAN,sp|P50395|GDIB_HUMAN,tr|Q5SX91|Q5SX91_HUMAN,tr|Q5SX87|Q5SX87_HUMAN" 4 947.4952 1.41 10816 8131 2 947.490051 474.7549 Rab GDP dissociation inhibitor alpha OS=Homo sapiens OX=9606 GN=GDI1 PE=1 SV=2 6 2133.9 - 2.53E+06 - - - -5.3984 - 1.236 0.263 - 144.6 1 2 0 -0.0051 8 0 0 0 1.05E+08 7.45E+07 - - - 1.6209 0.8557 221125_WJC_METTL3_EV_vs_WT_F02.08143.08143.2 0.0552 14-Jul R.ILSGVVTK.M "sp|P62280|RS11_HUMAN,tr|M0QZC5|M0QZC5_HUMAN" 2 815.5117 0.91 10818 8143 2 815.505715 408.7631 40S ribosomal protein S11 OS=Homo sapiens OX=9606 GN=RPS11 PE=1 SV=3 8.75 2135.7 - 1.02E+07 - - - -7.2825 - 1.555 0.2 - 110.3 1 2 0 -0.0059 8 0 0 0 3.85E+09 4.24E+09 - - - 1.8478 0.983 221125_WJC_METTL3_EV_vs_WT_F02.08146.08146.2 0.243 16-Jul K.ILESVAEGR.A "sp|Q9UJV9|DDX41_HUMAN,tr|A0A499FJW5|A0A499FJW5_HUMAN,tr|H0YA06|H0YA06_HUMAN,tr|D6RGI7|D6RGI7_HUMAN" 4 972.524 0.91 10819 8146 2 972.521442 487.2693 Probable ATP-dependent RNA helicase DDX41 OS=Homo sapiens OX=9606 GN=DDX41 PE=1 SV=2 4.53 2136.1 - 1.26E+06 - - - -2.6406 - 1.38 0.153 - 111.3 1 2 0 -0.0026 9 0 0 0 8.90E+07 9.79E+07 - - - 1.1021 0.9979 221125_WJC_METTL3_EV_vs_WT_F02.08149.08149.2 0.0109 16-Nov K.ILESVAEGR[166.11].A "sp|Q9UJV9|DDX41_HUMAN,tr|A0A499FJW5|A0A499FJW5_HUMAN,tr|H0YA06|H0YA06_HUMAN,tr|D6RGI7|D6RGI7_HUMAN" 4 982.5323 0.91 10820 8149 2 982.529961 492.2734 Probable ATP-dependent RNA helicase DDX41 OS=Homo sapiens OX=9606 GN=DDX41 PE=1 SV=2 4.53 2136.5 - 2.02E+06 - - - -2.3602 - 2.035 0.205 - 362.7 1 2 0 -0.0023 9 0 0 0 8.93E+07 9.81E+07 - - - 2.6099 0.9667 221125_WJC_METTL3_EV_vs_WT_F02.08159.08159.2 0.00171 12-Jun K.MDPVAYR.V "sp|P47897|SYQ_HUMAN,tr|B4DDN1|B4DDN1_HUMAN,tr|A0A1B0GTT3|A0A1B0GTT3_HUMAN,tr|A0A1B0GVU9|A0A1B0GVU9_HUMAN,tr|A0A0U1RQQ5|A0A0U1RQQ5_HUMAN" 5 850.4007 1.62 10823 8159 2 850.395325 426.2076 Glutamine--tRNA ligase OS=Homo sapiens OX=9606 GN=QARS1 PE=1 SV=1 5.59 2137.8 - 1.17E+06 - - - -6.3488 - 1.404 0.35 - 133.6 1 2 0 -0.0054 7 0 0 0 8.50E+07 5.25E+07 - - - 2.6996 0.997 221125_WJC_METTL3_EV_vs_WT_F02.08171.08171.2 0.466 12-Jun K.LVTDLTK.V "sp|P02768|ALBU_HUMAN,tr|B7WNR0|B7WNR0_HUMAN,tr|H0YA55|H0YA55_HUMAN,tr|A0A0C4DGB6|A0A0C4DGB6_HUMAN,tr|D6RHD5|D6RHD5_HUMAN,tr|C9JKR2|C9JKR2_HUMAN" 6 788.4644 752.78 10827 8171 2 788.464034 395.2395 Albumin OS=Homo sapiens OX=9606 GN=ALB PE=1 SV=2 5.84 2139.5 - 1.34E+07 - - - -0.4261 - 1.446 0.172 - 83.2 1 2 0 -0.0003 7 0 0 0 2.18E+09 2.90E+06 - - - 1.4799 0.9978 221125_WJC_METTL3_EV_vs_WT_F02.08174.08174.2 0.0163 14-Aug K.AVVPEMEK[136.11].R "sp|P0CG22|DR4L1_HUMAN,sp|Q6PKH6|DR4L2_HUMAN,sp|Q9BTZ2|DHRS4_HUMAN,tr|H0YLE1|H0YLE1_HUMAN,tr|A0A087WSZ6|A0A087WSZ6_HUMAN,tr|A0A087WXI8|A0A087WXI8_HUMAN,tr|H0YKN3|H0YKN3_HUMAN" 7 909.4721 1.61 10828 8174 2 909.470369 455.7433 Putative dehydrogenase\reductase SDR family member 4-like 1 OS=Homo sapiens OX=9606 GN=DHRS4L1 PE=5 SV=1 4.53 2139.9 - 1.02E+06 - - - -1.9077 - 1.532 0.267 - 245.1 1 2 0 -0.0017 8 0 0 0 7.55E+07 4.68E+07 - - - 2.299 0.9291 221125_WJC_METTL3_EV_vs_WT_F02.08183.08183.2 0.168 12-Jun K.LLIAAQK[136.11].Q "sp|O94905|ERLN2_HUMAN,sp|O75477|ERLN1_HUMAN,tr|E5RHW4|E5RHW4_HUMAN,tr|B0QZ43|B0QZ43_HUMAN,tr|E5RJ09|E5RJ09_HUMAN" 5 763.5047 0.001 10833 8183 2 763.503375 382.7596 Erlin-2 OS=Homo sapiens OX=9606 GN=ERLIN2 PE=1 SV=1 8.75 2141 - 4.02E+06 - - - -1.7682 - 1.233 0.001 - 99.4 1 2 0 -0.0014 7 0 0 0 0.00E+00 1.85E+08 - - - -0.2884 0.9941 221125_WJC_METTL3_EV_vs_WT_F02.08186.08186.2 0.569 12-Sep K.ITDVLAK.S "sp|Q9BQ75|CMS1_HUMAN,tr|C9J384|C9J384_HUMAN" 2 758.4538 0.53 10835 8186 2 758.452384 380.2342 Protein CMSS1 OS=Homo sapiens OX=9606 GN=CMSS1 PE=1 SV=2 5.84 2141.3 - 1.30E+06 - - - -1.8735 - 1.56 0.14 - 182 1 2 0 -0.0014 7 0 0 0 6.70E+07 1.26E+08 - - - 1.4836 0.9989 221125_WJC_METTL3_EV_vs_WT_F02.08189.08189.2 0.0609 12-Jun R.LASYLDK.V "sp|Q04695|K1C17_HUMAN,sp|Q99456|K1C12_HUMAN,sp|P13645|K1C10_HUMAN,sp|P02533|K1C14_HUMAN,sp|P08727|K1C19_HUMAN,sp|P35527|K1C9_HUMAN,sp|P08779|K1C16_HUMAN,sp|P19012|K1C15_HUMAN,tr|K7EPJ9|K7EPJ9_HUMAN,tr|C9JM50|C9JM50_HUMAN,tr|A0A1B0GVI3|A0A1B0GVI3_HUMAN,tr|A0A3B3ITG2|A0A3B3ITG2_HUMAN" 12 808.4331 1020.21 10837 8189 2 808.432286 405.2238 "Keratin, type I cytoskeletal 17 OS=Homo sapiens OX=9606 GN=KRT17 PE=1 SV=2" 5.83 2141.6 - 9.28E+08 - - - -0.9698 - 1.332 0.339 - 107.7 1 2 0 -0.0008 7 0 0 0 1.28E+11 1.25E+08 - - - 2.453 0.7868 221125_WJC_METTL3_EV_vs_WT_F02.08195.08195.2 13.2 14-Jul V.PPPPPIAR.A "sp|P07910|HNRPC_HUMAN,tr|B4DY08|B4DY08_HUMAN,tr|G3V575|G3V575_HUMAN,tr|G3V5V7|G3V5V7_HUMAN,tr|B2R5W2|B2R5W2_HUMAN,tr|G3V4C1|G3V4C1_HUMAN,tr|G3V576|G3V576_HUMAN,tr|G3V2D6|G3V2D6_HUMAN,tr|G3V4W0|G3V4W0_HUMAN,tr|G3V555|G3V555_HUMAN,tr|G3V2Q1|G3V2Q1_HUMAN" 11 843.4967 2.08 10841 8195 2 843.495419 422.7556 Heterogeneous nuclear ribonucleoproteins C1\C2 OS=Homo sapiens OX=9606 GN=HNRNPC PE=1 SV=4 10.18 2142.3 - 849640 - - - -1.4867 - 1.523 0.161 - 151.6 1 1 0 -0.0013 8 0 0 0 8.30E+07 3.99E+07 - - - 1.4985 0.9719 221125_WJC_METTL3_EV_vs_WT_F02.08214.08214.2 2.08 14-Jul R.VLSEDAIR[166.11].T "sp|P23919|KTHY_HUMAN,tr|H7C312|H7C312_HUMAN" 2 911.4952 1.28 10850 8214 2 911.495365 456.7549 Thymidylate kinase OS=Homo sapiens OX=9606 GN=DTYMK PE=1 SV=4 4.37 2144.7 - 918251 - - - 0.2183 - 1.223 0.041 - 147.7 1 2 0 0.0002 8 0 0 0 6.23E+07 4.86E+07 - - - -0.0491 0.9756 221125_WJC_METTL3_EV_vs_WT_F02.08223.08223.2 1.39 16-Jun K.IPPPIGTER.L "sp|Q8IWZ3|ANKH1_HUMAN,tr|A0A0A0MQZ8|A0A0A0MQZ8_HUMAN,tr|H0Y472|H0Y472_HUMAN,tr|H0Y7Y3|H0Y7Y3_HUMAN,tr|H0Y4P6|H0Y4P6_HUMAN,tr|H7C0V5|H7C0V5_HUMAN,tr|H0Y785|H0Y785_HUMAN,tr|H7C2E1|H7C2E1_HUMAN" 8 978.5498 1.66 10853 8223 2 978.548385 490.2822 Ankyrin repeat and KH domain-containing protein 1 OS=Homo sapiens OX=9606 GN=ANKHD1 PE=1 SV=1 6 2145.9 - 334095 - - - -1.4777 - 1.261 0.109 - 103.2 3 2 0 -0.0014 9 0 0 0 3.97E+07 2.39E+07 - - - 0.3034 0.9944 221125_WJC_METTL3_EV_vs_WT_F02.08227.08227.2 0.371 14-Aug R.YIATITDK.E "sp|O75179|ANR17_HUMAN,sp|Q8IWZ3|ANKH1_HUMAN,tr|E9PDP5|E9PDP5_HUMAN,tr|H0YM23|H0YM23_HUMAN,tr|H3BLS9|H3BLS9_HUMAN,tr|H0Y4P6|H0Y4P6_HUMAN,tr|H0YLQ3|H0YLQ3_HUMAN,tr|H7C2F5|H7C2F5_HUMAN" 8 923.4964 1.57 10855 8227 2 923.496002 462.7555 Ankyrin repeat domain-containing protein 17 OS=Homo sapiens OX=9606 GN=ANKRD17 PE=1 SV=3 5.83 2146.3 - 1.18E+06 - - - -0.4288 - 1.26 0.175 - 192.3 1 2 0 -0.0004 8 0 0 0 4.38E+07 2.78E+07 - - - 1.0304 0.988 221125_WJC_METTL3_EV_vs_WT_F02.08235.08235.2 0.732 14-Jun R.VLSEDAIR.T "sp|P23919|KTHY_HUMAN,tr|H7C312|H7C312_HUMAN" 2 901.4869 1.28 10858 8235 2 901.486386 451.7507 Thymidylate kinase OS=Homo sapiens OX=9606 GN=DTYMK PE=1 SV=4 4.37 2147.4 - 1.82E+06 - - - -0.5657 - 1.161 0.14 - 102.1 1 2 0 -0.0005 8 0 0 0 6.23E+07 4.86E+07 - - - 0.5251 0.901 221125_WJC_METTL3_EV_vs_WT_F02.08238.08238.2 0.83 12-Jun K.VFGNEIK[136.11].L "sp|P19338|NUCL_HUMAN,tr|A0A7I2V506|A0A7I2V506_HUMAN,tr|A0A7I2V699|A0A7I2V699_HUMAN,tr|A0A7I2V2U7|A0A7I2V2U7_HUMAN,tr|A0A7I2V3F3|A0A7I2V3F3_HUMAN,tr|A0A7I2V428|A0A7I2V428_HUMAN,tr|A0A7I2V349|A0A7I2V349_HUMAN,tr|H7BY16|H7BY16_HUMAN,tr|A0A7I2V5M5|A0A7I2V5M5_HUMAN,tr|A0A7I2V2S8|A0A7I2V2S8_HUMAN,tr|C9JLB1|C9JLB1_HUMAN" 11 813.4476 1.06 10859 8238 2 813.446531 407.7311 Nucleolin OS=Homo sapiens OX=9606 GN=NCL PE=1 SV=3 5.97 2147.8 - 2.04E+07 - - - -1.3191 - 1.091 0 - 87.4 1 2 0 -0.0011 7 0 0 0 2.69E+09 2.54E+09 - - - -0.6834 0.9533 221125_WJC_METTL3_EV_vs_WT_F02.08264.08264.2 6.88 12-Jul K.LDPITGR[166.11].S "sp|Q14103|HNRPD_HUMAN,tr|H0Y8G5|H0Y8G5_HUMAN,tr|D6RF44|D6RF44_HUMAN,tr|D6RD83|D6RD83_HUMAN,tr|D6RBQ9|D6RBQ9_HUMAN,tr|D6RAF8|D6RAF8_HUMAN,tr|H0YA96|H0YA96_HUMAN" 7 780.4369 0.98 10868 8264 2 780.435686 391.2257 Heterogeneous nuclear ribonucleoprotein D0 OS=Homo sapiens OX=9606 GN=HNRNPD PE=1 SV=1 5.84 2151.5 - 2.88E+07 - - - -1.585 - 1.151 0.058 - 273.6 1 2 0 -0.0012 7 0 0 0 1.87E+09 1.91E+09 - - - -0.0854 0.9992 221125_WJC_METTL3_EV_vs_WT_F02.08285.08285.2 0.00292 16-Aug K.VIASMTVGK.D "sp|Q10567|AP1B1_HUMAN,tr|C9J1E7|C9J1E7_HUMAN" 2 904.5052 0.85 10875 8285 2 904.50394 453.2599 AP-1 complex subunit beta-1 OS=Homo sapiens OX=9606 GN=AP1B1 PE=1 SV=2 8.72 2154.4 - 732856 - - - -1.3809 - 1.577 0.341 - 175.6 1 2 0 -0.0012 9 0 0 0 1.80E+07 2.11E+07 - - - 2.8771 0.9857 221125_WJC_METTL3_EV_vs_WT_F02.08287.08287.2 0.208 16-Jul R.VLAQDVYAK[136.11].D "sp|Q9NQX3|GEPH_HUMAN,tr|F5H039|F5H039_HUMAN" 2 1013.5637 0.76 10877 8287 2 1013.562066 507.7891 Gephyrin OS=Homo sapiens OX=9606 GN=GPHN PE=1 SV=1 5.81 2154.7 - 346445 - - - -1.6082 - 1.171 0.165 - 152.3 1 2 0 -0.0016 9 0 0 0 3.39E+07 4.46E+07 - - - 0.7159 0.9986 221125_WJC_METTL3_EV_vs_WT_F02.08293.08293.2 0.0078 14-Aug K.AVTEVLAR[166.11].T "sp|Q99961|SH3G1_HUMAN,tr|M0R0I3|M0R0I3_HUMAN,tr|M0QYE0|M0QYE0_HUMAN,tr|M0R2K6|M0R2K6_HUMAN" 4 867.5053 1.37 10879 8293 2 867.502886 434.7599 Endophilin-A2 OS=Homo sapiens OX=9606 GN=SH3GL1 PE=1 SV=1 6.05 2155.5 - 1.85E+06 - - - -2.8253 - 1.82 0.343 - 276.8 1 2 0 -0.0025 8 0 0 0 6.49E+08 4.75E+08 - - - 3.3797 0.9965 221125_WJC_METTL3_EV_vs_WT_F02.08298.08298.2 0.016 16-Aug R.VVLENEAVR[166.11].A sp|Q9UBF2|COPG2_HUMAN 1 1037.5745 0.34 10880 8298 2 1037.571904 519.7945 Coatomer subunit gamma-2 OS=Homo sapiens OX=9606 GN=COPG2 PE=1 SV=1 4.53 2156.2 - 748903 - - - -2.4817 - 1.294 0.333 - 153.4 1 2 0 -0.0026 9 0 0 0 1.09E+07 3.22E+07 - - - 2.2454 0.9989 221125_WJC_METTL3_EV_vs_WT_F02.08301.08301.2 0.00175 16-Aug R.VLAQDVYAK.D "sp|Q9NQX3|GEPH_HUMAN,tr|F5H039|F5H039_HUMAN" 2 1005.5495 0.76 10882 8301 2 1005.547974 503.782 Gephyrin OS=Homo sapiens OX=9606 GN=GPHN PE=1 SV=1 5.81 2156.6 - 429665 - - - -1.5136 - 1.407 0.365 - 229.5 1 2 0 -0.0015 9 0 0 0 3.39E+07 4.46E+07 - - - 2.7243 0.9875 221125_WJC_METTL3_EV_vs_WT_F02.08305.08305.2 0.259 16-Jun K.MMASGLTER[166.11].V sp|Q9UG63|ABCF2_HUMAN 1 1004.4659 0.48 10883 8305 2 1004.465105 503.2402 ATP-binding cassette sub-family F member 2 OS=Homo sapiens OX=9606 GN=ABCF2 PE=1 SV=2 5.75 2157.1 - 487717 - - - -0.7487 - 1.106 0.162 - 105.2 1 2 0 -0.0008 9 0 0 0 9.31E+06 1.95E+07 - - - 0.5288 0.8651 221125_WJC_METTL3_EV_vs_WT_F02.08310.08310.2 2.11 14-May R.TSIEVGVK.G sp|Q03052|PO3F1_HUMAN 1 831.4702 69.75 10885 8310 2 831.468927 416.7424 "POU domain, class 3, transcription factor 1 OS=Homo sapiens OX=9606 GN=POU3F1 PE=2 SV=3" 5.66 2157.7 - 1.83E+07 - - - -1.5106 - 1.119 0.008 - 88.2 4 2 0 -0.0013 8 0 0 0 9.64E+08 1.38E+07 - - - -0.8301 0.9986 221125_WJC_METTL3_EV_vs_WT_F02.08314.08314.2 0.306 16-Jun R.VPPPPPIAR.A "sp|P07910|HNRPC_HUMAN,tr|B4DY08|B4DY08_HUMAN,tr|G3V575|G3V575_HUMAN,tr|G3V5V7|G3V5V7_HUMAN,tr|B2R5W2|B2R5W2_HUMAN,tr|G3V4C1|G3V4C1_HUMAN,tr|G3V576|G3V576_HUMAN,tr|G3V2D6|G3V2D6_HUMAN,tr|G3V4W0|G3V4W0_HUMAN,tr|G3V555|G3V555_HUMAN,tr|G3V2Q1|G3V2Q1_HUMAN" 11 942.5651 1.65 10886 8314 2 942.563632 472.2898 Heterogeneous nuclear ribonucleoproteins C1\C2 OS=Homo sapiens OX=9606 GN=HNRNPC PE=1 SV=4 9.72 2158.3 - 2.06E+07 - - - -1.5437 - 1.336 0.349 - 131.4 1 2 0 -0.0015 9 0 0 0 3.44E+09 2.09E+09 - - - 2.4563 0.9987 221125_WJC_METTL3_EV_vs_WT_F02.08319.08319.2 0.175 16-Jul R.VPPPPPIAR[166.11].A "sp|P07910|HNRPC_HUMAN,tr|B4DY08|B4DY08_HUMAN,tr|G3V575|G3V575_HUMAN,tr|G3V5V7|G3V5V7_HUMAN,tr|B2R5W2|B2R5W2_HUMAN,tr|G3V4C1|G3V4C1_HUMAN,tr|G3V576|G3V576_HUMAN,tr|G3V2D6|G3V2D6_HUMAN,tr|G3V4W0|G3V4W0_HUMAN,tr|G3V555|G3V555_HUMAN,tr|G3V2Q1|G3V2Q1_HUMAN" 11 952.5734 1.65 10889 8319 2 952.571952 477.294 Heterogeneous nuclear ribonucleoproteins C1\C2 OS=Homo sapiens OX=9606 GN=HNRNPC PE=1 SV=4 9.72 2158.9 - 1.26E+07 - - - -1.475 - 1.321 0.363 - 166.3 1 2 0 -0.0014 9 0 0 0 3.39E+09 2.05E+09 - - - 2.5271 0.9616 221125_WJC_METTL3_EV_vs_WT_F02.08324.08324.2 5.01 12-Jun K.LDPITGR.S "sp|Q14103|HNRPD_HUMAN,tr|H0Y8G5|H0Y8G5_HUMAN,tr|D6RF44|D6RF44_HUMAN,tr|D6RD83|D6RD83_HUMAN,tr|D6RBQ9|D6RBQ9_HUMAN,tr|D6RAF8|D6RAF8_HUMAN,tr|H0YA96|H0YA96_HUMAN" 7 770.4287 0.98 10890 8324 2 770.42749 386.2216 Heterogeneous nuclear ribonucleoprotein D0 OS=Homo sapiens OX=9606 GN=HNRNPD PE=1 SV=1 5.84 2159.6 - 1.20E+07 - - - -1.5095 - 1.263 0.05 - 210.6 2 2 0 -0.0012 7 0 0 0 1.88E+09 1.91E+09 - - - 0.0153 0.9966 221125_WJC_METTL3_EV_vs_WT_F02.08326.08326.2 0.107 14-Jun R.FIMESGAK[136.11].G "sp|P23396|RS3_HUMAN,tr|H0YEU2|H0YEU2_HUMAN,tr|E9PL09|E9PL09_HUMAN" 3 889.4459 0.58 10891 8326 2 889.443883 445.7302 40S ribosomal protein S3 OS=Homo sapiens OX=9606 GN=RPS3 PE=1 SV=2 6 2159.8 - 8.78E+06 - - - -2.2553 - 1.191 0.349 - 84.6 1 2 0 -0.002 8 0 0 0 4.69E+08 8.11E+08 - - - 2.1453 0.9984 221125_WJC_METTL3_EV_vs_WT_F02.08336.08336.2 0.169 14-Sep R.VAAGLQIK[136.11].N "sp|Q14974|IMB1_HUMAN,tr|J3QR48|J3QR48_HUMAN" 2 806.5105 1.32 10895 8336 2 806.509589 404.2625 Importin subunit beta-1 OS=Homo sapiens OX=9606 GN=KPNB1 PE=1 SV=2 8.72 2161.2 - 5.49E+06 - - - -1.1779 - 1.679 0.212 - 231.4 1 2 0 -0.0009 8 0 0 0 3.60E+08 2.72E+08 - - - 2.1694 0.999 221125_WJC_METTL3_EV_vs_WT_F02.08338.08338.2 0.0118 14-Aug R.FIMESGAK.G "sp|P23396|RS3_HUMAN,tr|H0YEU2|H0YEU2_HUMAN,tr|E9PL09|E9PL09_HUMAN" 3 881.4317 0.58 10896 8338 2 881.430386 441.7231 40S ribosomal protein S3 OS=Homo sapiens OX=9606 GN=RPS3 PE=1 SV=2 6 2161.4 - 8.02E+06 - - - -1.4783 - 1.594 0.308 - 223.8 1 2 0 -0.0013 8 0 0 0 4.69E+08 8.11E+08 - - - 2.7217 0.9966 221125_WJC_METTL3_EV_vs_WT_F02.08347.08347.2 0.183 12-Jun K.VFESIGK.F "sp|P35232|PHB_HUMAN,tr|C9JZ20|C9JZ20_HUMAN,tr|E7ESE2|E7ESE2_HUMAN,tr|E9PCW0|E9PCW0_HUMAN,tr|C9JW96|C9JW96_HUMAN" 5 778.4225 1.28 10901 8347 2 778.422055 390.2185 Prohibitin OS=Homo sapiens OX=9606 GN=PHB PE=1 SV=1 5.97 2162.4 - 4.31E+06 - - - -0.5781 - 1.388 0.181 - 128 1 2 0 -0.0004 7 0 0 0 5.47E+08 4.28E+08 - - - 1.4166 0.9991 221125_WJC_METTL3_EV_vs_WT_F02.08352.08352.2 0.0102 14-Jul K.AVTEVLAR.T "sp|Q99961|SH3G1_HUMAN,tr|M0R0I3|M0R0I3_HUMAN,tr|M0QYE0|M0QYE0_HUMAN,tr|M0R2K6|M0R2K6_HUMAN" 4 857.4971 1.37 10904 8352 2 857.497169 429.7558 Endophilin-A2 OS=Homo sapiens OX=9606 GN=SH3GL1 PE=1 SV=1 6.05 2163 - 1.70E+07 - - - 0.119 - 1.428 0.325 - 186.9 1 2 0 0.0001 8 0 0 0 6.49E+08 4.75E+08 - - - 2.5159 0.999 221125_WJC_METTL3_EV_vs_WT_F02.08353.08353.2 0.0174 16-Jul K.LTPVAYGC[160.03]R.V "sp|Q16875|F263_HUMAN,tr|A0A1W2PR17|A0A1W2PR17_HUMAN,tr|Q5W015|Q5W015_HUMAN,tr|F2Z2I2|F2Z2I2_HUMAN,tr|H0Y483|H0Y483_HUMAN,tr|Q5VX20|Q5VX20_HUMAN" 6 1035.5172 3.15 10905 8353 2 1035.516803 518.7659 "6-phosphofructo-2-kinase\fructose-2,6-bisphosphatase 3 OS=Homo sapiens OX=9606 GN=PFKFB3 PE=1 SV=1" 8.22 2163.1 - 517581 - - - -0.3361 - 1.254 0.36 - 212.1 1 2 0 -0.0003 9 0 0 0 1.64E+07 5.20E+06 - - - 2.3547 0.9983 221125_WJC_METTL3_EV_vs_WT_F02.08357.08357.2 0.122 14-Jun R.AVVIVDDR[166.11].G "sp|P23246|SFPQ_HUMAN,sp|Q15233|NONO_HUMAN,tr|A0A7I2V535|A0A7I2V535_HUMAN,tr|A0A7I2V4N2|A0A7I2V4N2_HUMAN,tr|A0A7I2V464|A0A7I2V464_HUMAN,tr|A0A7P0MRW0|A0A7P0MRW0_HUMAN,tr|H7C367|H7C367_HUMAN,tr|C9IZL7|C9IZL7_HUMAN,tr|A0A7I2V4J2|A0A7I2V4J2_HUMAN,tr|A0A7I2V5Y7|A0A7I2V5Y7_HUMAN" 10 895.5003 0.81 10907 8357 2 895.499774 448.7574 "Splicing factor, proline- and glutamine-rich OS=Homo sapiens OX=9606 GN=SFPQ PE=1 SV=2" 4.21 2163.6 - 2.09E+06 - - - -0.5338 - 1.599 0.204 - 194.4 1 2 0 -0.0005 8 0 0 0 2.77E+09 3.42E+09 - - - 1.9632 0.9993 221125_WJC_METTL3_EV_vs_WT_F02.08363.08363.2 0.0185 16-Aug -.MLVAAAAER.N "sp|Q96S19|MTL26_HUMAN,tr|A0A087WYU2|A0A087WYU2_HUMAN,tr|H3BNB2|H3BNB2_HUMAN,tr|H3BS73|H3BS73_HUMAN" 4 930.4957 1.55 10909 8363 2 930.495907 466.2551 Methyltransferase-like 26 OS=Homo sapiens OX=9606 GN=METTL26 PE=1 SV=2 5.75 2164.4 - 567801 - - - 0.2364 - 1.691 0.285 - 259.9 1 2 0 0.0002 9 0 0 0 2.29E+07 1.48E+07 - - - 2.6657 0.9989 221125_WJC_METTL3_EV_vs_WT_F02.08364.08364.2 0.00354 16-Jun R.SMMYSGELK[136.11].F "sp|P20839|IMDH1_HUMAN,tr|C9J381|C9J381_HUMAN,tr|A0A3B3IRL5|A0A3B3IRL5_HUMAN" 3 1052.4762 4.51 10910 8364 2 1052.476717 527.2454 Inosine-5'-monophosphate dehydrogenase 1 OS=Homo sapiens OX=9606 GN=IMPDH1 PE=1 SV=2 5.72 2164.5 - 237528 - - - 0.4884 - 1.181 0.386 - 89.2 1 2 0 0.0005 9 0 0 0 2.20E+07 4.89E+06 - - - 2.3731 0.9987 221125_WJC_METTL3_EV_vs_WT_F02.08402.08402.2 0.0255 12-Jun R.VLLPTQK.L sp|Q96GA3|LTV1_HUMAN 1 797.5011 4.55 10923 8402 2 797.501647 399.7578 Protein LTV1 homolog OS=Homo sapiens OX=9606 GN=LTV1 PE=1 SV=1 8.72 2169.8 - 2.88E+06 - - - 0.6984 - 1.297 0.325 - 145.9 1 2 0 0.0006 7 0 0 0 2.38E+08 5.23E+07 - - - 2.2653 0.9507 221125_WJC_METTL3_EV_vs_WT_F02.08407.08407.2 3.02 12-Jun K.LPEELGR.D "sp|Q01082|SPTB2_HUMAN,sp|O43861|ATP9B_HUMAN,sp|Q9HCG7|GBA2_HUMAN,tr|F6XUP2|F6XUP2_HUMAN,tr|A0A087WUZ3|A0A087WUZ3_HUMAN" 5 812.4392 3.18 10926 8407 2 812.43717 407.2269 "Spectrin beta chain, non-erythrocytic 1 OS=Homo sapiens OX=9606 GN=SPTBN1 PE=1 SV=2" 4.53 2170.4 - 1.15E+06 - - - -2.5208 - 1.228 0.082 - 113.4 1 2 0 -0.002 7 0 0 0 1.16E+08 3.66E+07 - - - 0.2968 0.9981 221125_WJC_METTL3_EV_vs_WT_F02.08408.08408.2 0.0411 14-Aug R.AVVIVDDR.G "sp|P23246|SFPQ_HUMAN,sp|Q15233|NONO_HUMAN,tr|A0A7I2V535|A0A7I2V535_HUMAN,tr|A0A7I2V4N2|A0A7I2V4N2_HUMAN,tr|A0A7I2V464|A0A7I2V464_HUMAN,tr|A0A7P0MRW0|A0A7P0MRW0_HUMAN,tr|H7C367|H7C367_HUMAN,tr|C9IZL7|C9IZL7_HUMAN,tr|A0A7I2V4J2|A0A7I2V4J2_HUMAN,tr|A0A7I2V5Y7|A0A7I2V5Y7_HUMAN" 10 885.492 0.81 10927 8408 2 885.48965 443.7533 "Splicing factor, proline- and glutamine-rich OS=Homo sapiens OX=9606 GN=SFPQ PE=1 SV=2" 4.21 2170.5 - 6.83E+07 - - - -2.6336 - 1.914 0.257 - 387.9 1 2 0 -0.0023 8 0 0 0 2.77E+09 3.42E+09 - - - 2.8964 0.8487 221125_WJC_METTL3_EV_vs_WT_F02.08413.08413.2 1.6 14-Jun K.LPEEPITR[166.11].W "sp|Q9BYD2|RM09_HUMAN,tr|Q5SZR1|Q5SZR1_HUMAN" 2 963.5265 1.5 10930 8413 2 963.524936 482.7705 "39S ribosomal protein L9, mitochondrial OS=Homo sapiens OX=9606 GN=MRPL9 PE=1 SV=2" 4.53 2171.1 - 857100 - - - -1.5879 - 1.023 0.001 - 114 1 2 0 -0.0015 8 0 0 0 3.55E+07 2.36E+07 - - - -0.8835 0.9454 221125_WJC_METTL3_EV_vs_WT_F02.08414.08414.2 3.13 12-Jun K.VFESIGK[136.11].F "sp|P35232|PHB_HUMAN,tr|C9JZ20|C9JZ20_HUMAN,tr|E7ESE2|E7ESE2_HUMAN,tr|E9PCW0|E9PCW0_HUMAN,tr|C9JW96|C9JW96_HUMAN" 5 786.4367 2.16 10931 8414 2 786.435749 394.2256 Prohibitin OS=Homo sapiens OX=9606 GN=PHB PE=1 SV=1 5.97 2171.1 - 4.86E+06 - - - -1.2156 - 1.025 0.076 - 106.1 1 2 0 -0.001 7 0 0 0 1.01E+09 4.66E+08 - - - -0.3197 0.9988 221125_WJC_METTL3_EV_vs_WT_F02.08428.08428.2 0.0413 14-Sep K.LIEVDDER[166.11].K "sp|P62753|RS6_HUMAN,tr|A2A3R7|A2A3R7_HUMAN" 2 997.4956 1.07 10937 8428 2 997.492362 499.7551 40S ribosomal protein S6 OS=Homo sapiens OX=9606 GN=RPS6 PE=1 SV=1 3.92 2172.9 - 1.05E+06 - - - -3.206 - 1.88 0.403 - 313.6 1 2 0 -0.0032 8 0 0 0 2.08E+08 1.94E+08 - - - 3.9204 0.9985 221125_WJC_METTL3_EV_vs_WT_F02.08439.08439.2 0.0041 14-Aug K.LVSEYMSK[136.11].K sp|P11766|ADHX_HUMAN 1 963.4827 1.32 10941 8439 2 963.481752 482.7486 Alcohol dehydrogenase class-3 OS=Homo sapiens OX=9606 GN=ADH5 PE=1 SV=4 6 2174.3 - 898621 - - - -0.9518 - 1.131 0.372 - 189.3 1 2 0 -0.0009 8 0 0 0 3.75E+07 2.84E+07 - - - 2.1596 0.9823 221125_WJC_METTL3_EV_vs_WT_F02.08461.08461.2 3.04 12-Jul R.IILEAEK.M "sp|Q15382|RHEB_HUMAN,sp|O75116|ROCK2_HUMAN,tr|C9J931|C9J931_HUMAN,tr|E9PF63|E9PF63_HUMAN,tr|Q14DU5|Q14DU5_HUMAN" 5 814.48 0.98 10943 8461 2 814.477592 408.2473 GTP-binding protein Rheb OS=Homo sapiens OX=9606 GN=RHEB PE=1 SV=1 4.53 2177.9 - 1.29E+06 - - - -2.981 - 1.404 0.154 - 128.1 1 2 0 -0.0024 7 0 0 0 1.10E+08 1.11E+08 - - - 1.2529 0.8068 221125_WJC_METTL3_EV_vs_WT_F02.08468.08468.2 28.6 16-May K.IPPPIGTER.L "sp|Q8IWZ3|ANKH1_HUMAN,tr|A0A0A0MQZ8|A0A0A0MQZ8_HUMAN,tr|H0Y472|H0Y472_HUMAN,tr|H0Y7Y3|H0Y7Y3_HUMAN,tr|H0Y4P6|H0Y4P6_HUMAN,tr|H7C0V5|H7C0V5_HUMAN,tr|H0Y785|H0Y785_HUMAN,tr|H7C2E1|H7C2E1_HUMAN" 8 978.5498 3.52 10945 8468 2 978.550456 490.2822 Ankyrin repeat and KH domain-containing protein 1 OS=Homo sapiens OX=9606 GN=ANKHD1 PE=1 SV=1 6 2179 - 1.09E+06 - - - 0.6387 - 1.089 0.003 - 65.7 22 2 0 0.0006 9 0 0 0 4.23E+07 1.20E+07 - - - -1.29 0.9299 221125_WJC_METTL3_EV_vs_WT_F02.08477.08477.2 2.24 12-Jul R.IILEAEK[136.11].M "sp|Q15382|RHEB_HUMAN,sp|O75116|ROCK2_HUMAN,tr|C9J931|C9J931_HUMAN,tr|E9PF63|E9PF63_HUMAN,tr|Q14DU5|Q14DU5_HUMAN" 5 822.4942 1.02 10948 8477 2 822.490099 412.2544 GTP-binding protein Rheb OS=Homo sapiens OX=9606 GN=RHEB PE=1 SV=1 4.53 2180.1 - 2.90E+06 - - - -5.0104 - 1.61 0.1 - 158 1 2 0 -0.0041 7 0 0 0 1.10E+08 1.08E+08 - - - 1.2873 0.9064 221125_WJC_METTL3_EV_vs_WT_F02.08479.08479.2 3.55 14-Aug R.AITSAYYR[166.11].G "sp|Q15907|RB11B_HUMAN,sp|P62491|RB11A_HUMAN,sp|P57735|RAB25_HUMAN,tr|H3BMH2|H3BMH2_HUMAN,tr|H3BSC1|H3BSC1_HUMAN" 5 953.4846 1.01 10949 8479 2 953.482607 477.7496 Ras-related protein Rab-11B OS=Homo sapiens OX=9606 GN=RAB11B PE=1 SV=4 8.63 2180.4 - 4.36E+06 - - - -2.0913 - 1.09 0.049 - 284.3 1 2 0 -0.002 8 0 0 0 2.00E+08 1.97E+08 - - - -0.3378 0.9994 221125_WJC_METTL3_EV_vs_WT_F02.08490.08490.2 0.0772 16-Sep K.IIEVGDTPK.D "sp|P61619|S61A1_HUMAN,sp|Q9H9S3|S61A2_HUMAN,tr|H7C069|H7C069_HUMAN,tr|C9JXC6|C9JXC6_HUMAN,tr|F2Z2C7|F2Z2C7_HUMAN,tr|F8W776|F8W776_HUMAN,tr|H7C1Q9|H7C1Q9_HUMAN,tr|C9JJV4|C9JJV4_HUMAN,tr|A6NIF9|A6NIF9_HUMAN,tr|A6NK38|A6NK38_HUMAN,tr|Q8TC24|Q8TC24_HUMAN,tr|B4DR61|B4DR61_HUMAN" 12 970.5335 0.21 10953 8490 2 970.532159 486.274 Protein transport protein Sec61 subunit alpha isoform 1 OS=Homo sapiens OX=9606 GN=SEC61A1 PE=1 SV=2 4.37 2181.8 - 507636 - - - -1.3941 - 1.863 0.325 - 222.8 1 2 0 -0.0014 9 0 0 0 8.12E+06 3.79E+07 - - - 3.241 0.9984 221125_WJC_METTL3_EV_vs_WT_F02.08493.08493.2 0.0564 14-Jul R.IFEPPPPK.K sp|O43143|DHX15_HUMAN 1 923.5117 0.99 10954 8493 2 923.511318 462.7631 Pre-mRNA-splicing factor ATP-dependent RNA helicase DHX15 OS=Homo sapiens OX=9606 GN=DHX15 PE=1 SV=2 6 2182.2 - 793320 - - - -0.3638 - 1.461 0.246 - 173.4 1 2 0 -0.0003 8 0 0 0 2.05E+08 2.07E+08 - - - 2.0013 0.993 221125_WJC_METTL3_EV_vs_WT_F02.08495.08495.2 0.333 14-Jul R.AITSAYYR.G "sp|Q15907|RB11B_HUMAN,sp|P62491|RB11A_HUMAN,sp|P57735|RAB25_HUMAN,tr|H3BMH2|H3BMH2_HUMAN,tr|H3BSC1|H3BSC1_HUMAN" 5 943.4763 1.01 10956 8495 2 943.475019 472.7454 Ras-related protein Rab-11B OS=Homo sapiens OX=9606 GN=RAB11B PE=1 SV=4 8.63 2182.4 - 6.94E+06 - - - -1.3906 - 1.233 0.197 - 189 1 2 0 -0.0013 8 0 0 0 2.00E+08 1.97E+08 - - - 1.1273 0.9718 221125_WJC_METTL3_EV_vs_WT_F02.08501.08501.2 1.89 14-Aug K.VIDPVAPR.Y "sp|P07814|SYEP_HUMAN,tr|V9GYZ6|V9GYZ6_HUMAN" 2 865.5022 1.12 10960 8501 2 865.501236 433.7584 Bifunctional glutamate\proline--tRNA ligase OS=Homo sapiens OX=9606 GN=EPRS1 PE=1 SV=5 5.81 2183 - 3.04E+06 - - - -1.0583 - 1.207 0.062 - 221.3 1 2 0 -0.0009 8 0 0 0 4.48E+08 3.99E+08 - - - 0.0661 0.9404 221125_WJC_METTL3_EV_vs_WT_F02.08506.08506.2 4.18 12-May K.EQSIVEK[136.11].F "sp|Q86U44|MTA70_HUMAN,tr|H0YFV6|H0YFV6_HUMAN" 2 839.448 0 10964 8506 2 839.447473 420.7313 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 4.53 2183.5 - 4.49E+06 - - - -0.6254 - 1.176 0.019 - 137.3 3 2 0 -0.0005 7 0 0 0 3.71E+06 9.47E+08 - - - -0.5183 0.998 221125_WJC_METTL3_EV_vs_WT_F02.08508.08508.2 0.0994 14-Aug K.VIDPVAPR[166.11].Y "sp|P07814|SYEP_HUMAN,tr|V9GYZ6|V9GYZ6_HUMAN" 2 875.5104 1.12 10965 8508 2 875.511186 438.7625 Bifunctional glutamate\proline--tRNA ligase OS=Homo sapiens OX=9606 GN=EPRS1 PE=1 SV=5 5.81 2183.7 - 4.22E+06 - - - 0.8726 - 1.295 0.291 - 266.9 1 2 0 0.0008 8 0 0 0 4.48E+08 3.99E+08 - - - 1.9697 0.9789 221125_WJC_METTL3_EV_vs_WT_F02.08509.08509.2 1.11 14-Jun K.EVGSIIGK[136.11].K "sp|P57721|PCBP3_HUMAN,sp|P57723|PCBP4_HUMAN,sp|Q15366|PCBP2_HUMAN,sp|Q15365|PCBP1_HUMAN,tr|F8VTZ0|F8VTZ0_HUMAN,tr|C9JTY5|C9JTY5_HUMAN,tr|C9J7A9|C9J7A9_HUMAN,tr|F8W1G6|F8W1G6_HUMAN,tr|E9PFP8|E9PFP8_HUMAN,tr|C9IZV9|C9IZV9_HUMAN,tr|C9J0A4|C9J0A4_HUMAN,tr|J3QT27|J3QT27_HUMAN,tr|F8VZX2|F8VZX2_HUMAN,tr|F8W0G4|F8W0G4_HUMAN,tr|H3BSP4|H3BSP4_HUMAN,tr|C9J5V4|C9J5V4_HUMAN,tr|C9K0A2|C9K0A2_HUMAN,tr|C9JZY3|C9JZY3_HUMAN,tr|F8WC71|F8WC71_HUMAN,tr|C9JSA6|C9JSA6_HUMAN,tr|H3BRU6|H3BRU6_HUMAN" 21 809.4738 3.49 10966 8509 2 809.473194 405.7442 Poly(rC)-binding protein 3 OS=Homo sapiens OX=9606 GN=PCBP3 PE=1 SV=2 6.1 2183.8 - 1.56E+06 - - - -0.7721 - 1.156 0.114 - 73.6 2 2 0 -0.0006 8 0 0 0 2.45E+08 7.01E+07 - - - 0.1855 0.9981 221125_WJC_METTL3_EV_vs_WT_F02.08514.08514.2 0.467 12-Aug R.LEELYTK[136.11].K "sp|Q9UNM6|PSD13_HUMAN,tr|J3KNQ3|J3KNQ3_HUMAN,tr|F8W8J6|F8W8J6_HUMAN,tr|E9PPD2|E9PPD2_HUMAN,tr|E9PL38|E9PL38_HUMAN,tr|E9PQG3|E9PQG3_HUMAN,tr|A0A087WUL9|A0A087WUL9_HUMAN" 7 902.484 3.18 10969 8514 2 902.483394 452.2493 26S proteasome non-ATPase regulatory subunit 13 OS=Homo sapiens OX=9606 GN=PSMD13 PE=1 SV=2 4.53 2184.4 - 2.59E+06 - - - -0.7258 - 1.801 0.137 - 223.1 1 2 0 -0.0007 7 0 0 0 1.78E+08 5.60E+07 - - - 1.9169 0.9947 221125_WJC_METTL3_EV_vs_WT_F02.08530.08530.2 0.00926 12-Aug K.SPELLAR[166.11].Y "sp|Q13616|CUL1_HUMAN,tr|A0A0C4DGX4|A0A0C4DGX4_HUMAN,tr|A0A590UJ21|A0A590UJ21_HUMAN,tr|A0A590UJ50|A0A590UJ50_HUMAN,tr|A0A590UJR3|A0A590UJR3_HUMAN,tr|A0A590UJ56|A0A590UJ56_HUMAN,tr|A0A590UJC4|A0A590UJC4_HUMAN,tr|A0A590UK34|A0A590UK34_HUMAN" 8 794.4526 1.07 10977 8530 2 794.454883 398.2336 Cullin-1 OS=Homo sapiens OX=9606 GN=CUL1 PE=1 SV=2 5.72 2186.5 - 925153 - - - 2.9077 - 1.391 0.285 - 304.6 1 2 0 0.0023 7 0 0 0 6.81E+07 6.39E+07 - - - 2.191 0.9994 221125_WJC_METTL3_EV_vs_WT_F02.08536.08536.2 0.00584 14-Jul R.IFEPPPPK[136.11].K sp|O43143|DHX15_HUMAN 1 931.5259 1.1 10981 8536 2 931.527054 466.7702 Pre-mRNA-splicing factor ATP-dependent RNA helicase DHX15 OS=Homo sapiens OX=9606 GN=DHX15 PE=1 SV=2 6 2187.3 - 919977 - - - 1.2882 - 1.637 0.384 - 196.4 1 2 0 0.0012 8 0 0 0 1.93E+08 1.75E+08 - - - 3.3633 0.9965 221125_WJC_METTL3_EV_vs_WT_F02.08547.08547.2 0.354 16-Jun R.VPPPPPIAR.A "sp|P07910|HNRPC_HUMAN,tr|B4DY08|B4DY08_HUMAN,tr|G3V575|G3V575_HUMAN,tr|G3V5V7|G3V5V7_HUMAN,tr|B2R5W2|B2R5W2_HUMAN,tr|G3V4C1|G3V4C1_HUMAN,tr|G3V576|G3V576_HUMAN,tr|G3V2D6|G3V2D6_HUMAN,tr|G3V4W0|G3V4W0_HUMAN,tr|G3V555|G3V555_HUMAN,tr|G3V2Q1|G3V2Q1_HUMAN" 11 942.5651 1.8 10987 8547 2 942.566764 472.2898 Heterogeneous nuclear ribonucleoproteins C1\C2 OS=Homo sapiens OX=9606 GN=HNRNPC PE=1 SV=4 9.72 2188.8 - 4.53E+06 - - - 1.7792 - 1.214 0.311 - 133.2 1 2 0 0.0017 9 0 0 0 5.71E+08 3.17E+08 - - - 1.8985 0.99 221125_WJC_METTL3_EV_vs_WT_F02.08549.08549.2 0.256 16-Jun R.VPPPPPIAR[166.11].A "sp|P07910|HNRPC_HUMAN,tr|B4DY08|B4DY08_HUMAN,tr|G3V575|G3V575_HUMAN,tr|G3V5V7|G3V5V7_HUMAN,tr|B2R5W2|B2R5W2_HUMAN,tr|G3V4C1|G3V4C1_HUMAN,tr|G3V576|G3V576_HUMAN,tr|G3V2D6|G3V2D6_HUMAN,tr|G3V4W0|G3V4W0_HUMAN,tr|G3V555|G3V555_HUMAN,tr|G3V2Q1|G3V2Q1_HUMAN" 11 952.5734 1.8 10988 8549 2 952.574682 477.294 Heterogeneous nuclear ribonucleoproteins C1\C2 OS=Homo sapiens OX=9606 GN=HNRNPC PE=1 SV=4 9.72 2189 - 2.65E+06 - - - 1.391 - 1.292 0.158 - 134.1 1 2 0 0.0013 9 0 0 0 5.64E+08 3.13E+08 - - - 0.9487 0.9814 221125_WJC_METTL3_EV_vs_WT_F02.08559.08559.2 0.00769 14-Aug R.ILGPGLNK[136.11].A sp|P62906|RL10A_HUMAN 1 818.5105 1.05 10992 8559 2 818.512662 410.2625 60S ribosomal protein L10a OS=Homo sapiens OX=9606 GN=RPL10A PE=1 SV=2 8.75 2190.5 - 1.55E+06 - - - 2.5937 - 1.716 0.05 - 152.4 1 2 0 0.0021 8 0 0 0 2.57E+09 2.46E+09 - - - 1.0382 0.9977 221125_WJC_METTL3_EV_vs_WT_F02.08568.08568.2 0.38 14-Jul K.VGVNGFGR.L sp|P04406|G3P_HUMAN 1 804.4242 0.98 10995 8568 2 804.424502 403.2194 Glyceraldehyde-3-phosphate dehydrogenase OS=Homo sapiens OX=9606 GN=GAPDH PE=1 SV=3 9.72 2191.7 - 4.50E+06 - - - 0.3307 - 1.412 0.223 - 118.2 1 2 0 0.0003 8 0 0 0 1.53E+10 1.57E+10 - - - 1.7285 0.9856 221125_WJC_METTL3_EV_vs_WT_F02.08569.08569.2 0.0189 14-Jul R.LPVEEAYK.R sp|P15924|DESP_HUMAN 1 947.4964 5.52 10996 8569 2 947.49722 474.7555 Desmoplakin OS=Homo sapiens OX=9606 GN=DSP PE=1 SV=3 4.53 2191.8 - 822489 - - - 0.8675 - 1.444 0.05 - 214.3 1 2 0 0.0008 8 0 0 0 5.14E+08 9.31E+07 - - - 0.5182 0.9956 221125_WJC_METTL3_EV_vs_WT_F02.08572.08572.2 0.0275 16-Aug K.FIASTGMDR[166.11].S "sp|Q9UMS4|PRP19_HUMAN,tr|H0YGZ5|H0YGZ5_HUMAN" 2 1006.4781 1.19 10997 8572 2 1006.479062 504.2463 Pre-mRNA-processing factor 19 OS=Homo sapiens OX=9606 GN=PRPF19 PE=1 SV=1 5.84 2192.2 - 1.96E+06 - - - 0.92 - 1.303 0.212 - 214.3 1 2 0 0.0009 9 0 0 0 5.18E+08 4.37E+08 - - - 1.3722 0.9903 221125_WJC_METTL3_EV_vs_WT_F02.08573.08573.2 0.483 16-Jul R.SLPAAAMAR.A tr|H7BZT1|H7BZT1_HUMAN 1 886.4695 0.27 10998 8573 2 886.470413 444.242 Splicing factor 1 (Fragment) OS=Homo sapiens OX=9606 GN=SF1 PE=1 SV=1 9.47 2192.3 - 882970 - - - 1.0615 - 1.242 0.16 - 146.2 1 2 0 0.0009 9 0 0 0 7.50E+07 2.75E+08 - - - 0.8495 0.8305 221125_WJC_METTL3_EV_vs_WT_F02.08577.08577.2 4.96 12-Jul R.LPDGLTR[166.11].R "sp|P33992|MCM5_HUMAN,sp|Q15032|R3HD1_HUMAN,tr|B1AHB1|B1AHB1_HUMAN,tr|A0A804HIA8|A0A804HIA8_HUMAN,tr|H7C207|H7C207_HUMAN" 5 780.4369 1.16 11001 8577 2 780.439279 391.2257 DNA replication licensing factor MCM5 OS=Homo sapiens OX=9606 GN=MCM5 PE=1 SV=5 5.84 2192.8 - 1.05E+06 - - - 3.0188 - 1.164 0.021 - 103.7 1 2 0 0.0024 7 0 0 0 4.16E+09 3.58E+09 - - - -0.3234 0.995 221125_WJC_METTL3_EV_vs_WT_F02.08578.08578.2 0.0689 16-Jul K.FIASTGMDR.S "sp|Q9UMS4|PRP19_HUMAN,tr|H0YGZ5|H0YGZ5_HUMAN" 2 996.4699 1.19 11002 8578 2 996.47041 499.2422 Pre-mRNA-processing factor 19 OS=Homo sapiens OX=9606 GN=PRPF19 PE=1 SV=1 5.84 2192.8 - 2.11E+06 - - - 0.5459 - 1.362 0.167 - 163.2 1 2 0 0.0005 9 0 0 0 5.18E+08 4.37E+08 - - - 1.1681 0.8598 221125_WJC_METTL3_EV_vs_WT_F02.08586.08586.2 8.32 12-Aug L.LDGILDK.L "sp|Q9BXD5|NPL_HUMAN,sp|Q96A49|SYAP1_HUMAN,tr|A0A087WZ70|A0A087WZ70_HUMAN" 3 772.4331 1.27 11007 8586 2 772.432952 387.2238 N-acetylneuraminate lyase OS=Homo sapiens OX=9606 GN=NPL PE=1 SV=1 4.21 2193.7 - 1.18E+06 - - - -0.1528 - 1.608 0.136 - 162.4 1 1 0 -0.0001 7 0 0 0 4.58E+09 3.59E+09 - - - 1.5505 0.9997 221125_WJC_METTL3_EV_vs_WT_F02.08590.08590.2 0.0569 14-Sep R.VFTGVVTK.L "sp|Q8IX12|CCAR1_HUMAN,tr|F5H7M9|F5H7M9_HUMAN,tr|F5H2E6|F5H2E6_HUMAN,tr|A0A0C4DGG8|A0A0C4DGG8_HUMAN,tr|F5H3E1|F5H3E1_HUMAN" 5 849.496 4.14 11008 8590 2 849.495672 425.7553 Cell division cycle and apoptosis regulator protein 1 OS=Homo sapiens OX=9606 GN=CCAR1 PE=1 SV=2 8.72 2194.2 - 9.11E+06 - - - -0.3908 - 1.907 0.329 - 236.3 1 2 0 -0.0003 8 0 0 0 1.27E+09 3.06E+08 - - - 3.4178 0.9995 221125_WJC_METTL3_EV_vs_WT_F02.08598.08598.2 0.0198 12-May R.MGYMDPR[166.11].E "sp|P23246|SFPQ_HUMAN,tr|H0Y9K7|H0Y9K7_HUMAN,tr|H0Y9U2|H0Y9U2_HUMAN" 3 878.3654 0.88 11010 8598 2 878.364413 440.19 "Splicing factor, proline- and glutamine-rich OS=Homo sapiens OX=9606 GN=SFPQ PE=1 SV=2" 5.59 2195.4 - 2.06E+06 - - - -1.1396 - 1.142 0.506 - 95.5 1 2 0 -0.001 7 0 0 0 1.51E+08 1.72E+08 - - - 3.1987 0.998 221125_WJC_METTL3_EV_vs_WT_F02.08604.08604.2 0.0373 14-Jul R.VFTGVVTK[136.11].L "sp|Q8IX12|CCAR1_HUMAN,tr|F5H7M9|F5H7M9_HUMAN,tr|F5H2E6|F5H2E6_HUMAN,tr|A0A0C4DGG8|A0A0C4DGG8_HUMAN,tr|F5H3E1|F5H3E1_HUMAN" 5 857.5102 4.18 11012 8604 2 857.508973 429.7624 Cell division cycle and apoptosis regulator protein 1 OS=Homo sapiens OX=9606 GN=CCAR1 PE=1 SV=2 8.72 2196.2 - 5.55E+06 - - - -1.4356 - 1.378 0.283 - 122.6 1 2 0 -0.0012 8 0 0 0 1.25E+09 2.99E+08 - - - 2.0979 0.9921 221125_WJC_METTL3_EV_vs_WT_F02.08609.08609.2 0.638 12-Apr R.MGYMDPR.E "sp|P23246|SFPQ_HUMAN,tr|H0Y9K7|H0Y9K7_HUMAN,tr|H0Y9U2|H0Y9U2_HUMAN" 3 868.3571 0.88 11013 8609 2 868.354287 435.1858 "Splicing factor, proline- and glutamine-rich OS=Homo sapiens OX=9606 GN=SFPQ PE=1 SV=2" 5.59 2197 - 2.25E+06 - - - -3.2901 - 0.958 0.428 - 78.1 1 2 0 -0.0029 7 0 0 0 1.50E+08 1.71E+08 - - - 2.0654 0.989 221125_WJC_METTL3_EV_vs_WT_F02.08626.08626.2 0.0409 12-Jun R.FAQVLEK[136.11].E sp|Q6P1M0|S27A4_HUMAN 1 841.4789 0.26 11019 8626 2 841.476937 421.7467 Long-chain fatty acid transport protein 4 OS=Homo sapiens OX=9606 GN=SLC27A4 PE=1 SV=1 6 2199.2 - 502190 - - - -2.3376 - 1.405 0.155 - 82.4 1 2 0 -0.002 7 0 0 0 4.18E+07 1.61E+08 - - - 1.2626 0.9961 221125_WJC_METTL3_EV_vs_WT_F02.08628.08628.2 0.443 12-Jun K.LFVETGK.A "sp|Q9Y3D9|RT23_HUMAN,tr|J3QLR8|J3QLR8_HUMAN" 2 792.4382 1.22 11020 8628 2 792.43791 397.2264 "28S ribosomal protein S23, mitochondrial OS=Homo sapiens OX=9606 GN=MRPS23 PE=1 SV=2" 6 2199.4 - 2.15E+06 - - - -0.3092 - 1.163 0.239 - 110.7 1 2 0 -0.0002 7 0 0 0 2.52E+08 2.07E+08 - - - 1.2846 0.9718 221125_WJC_METTL3_EV_vs_WT_F02.08635.08635.2 0.228 14-Jul K.ALPAPIEK.T "sp|P01860|IGHG3_HUMAN,sp|P01857|IGHG1_HUMAN,tr|A0A4W9A917|A0A4W9A917_HUMAN,tr|A0A286YES1|A0A286YES1_HUMAN,tr|A0A0A0MS08|A0A0A0MS08_HUMAN,tr|A0A0A0MS07|A0A0A0MS07_HUMAN" 6 837.496 302.08 11024 8635 2 837.492599 419.7553 Immunoglobulin heavy constant gamma 3 OS=Homo sapiens OX=9606 GN=IGHG3 PE=1 SV=2 6.05 2200.2 - 1.96E+06 - - - -4.0657 - 1.308 0.222 - 133.3 1 2 0 -0.0034 8 0 0 0 4.56E+08 1.51E+06 - - - 1.4894 0.999 221125_WJC_METTL3_EV_vs_WT_F02.08639.08639.2 0.00988 14-Sep K.VGVNGFGR[166.11].L sp|P04406|G3P_HUMAN 1 814.4325 0.98 11026 8639 2 814.430104 408.2235 Glyceraldehyde-3-phosphate dehydrogenase OS=Homo sapiens OX=9606 GN=GAPDH PE=1 SV=3 9.72 2200.6 - 3.92E+08 - - - -2.9493 - 2.002 0.373 - 207.7 1 2 0 -0.0024 8 0 0 0 1.53E+10 1.57E+10 - - - 3.8887 0.9957 221125_WJC_METTL3_EV_vs_WT_F02.08651.08651.2 0.259 16-Jul R.GVYSEETLR.A "sp|Q16891|MIC60_HUMAN,tr|B9A067|B9A067_HUMAN,tr|A0A087WYS0|A0A087WYS0_HUMAN,tr|C9J406|C9J406_HUMAN,tr|H7C463|H7C463_HUMAN" 5 1052.5138 0.47 11031 8651 2 1052.512525 527.2642 MICOS complex subunit MIC60 OS=Homo sapiens OX=9606 GN=IMMT PE=1 SV=1 4.53 2202.2 - 401948 - - - -1.2484 - 1.201 0.252 - 164.2 1 2 0 -0.0013 9 0 0 0 1.65E+07 3.50E+07 - - - 1.4317 0.9822 221125_WJC_METTL3_EV_vs_WT_F02.08654.08654.2 0.41 14-Jun K.ILVPEGTR.D "sp|P10515|ODP2_HUMAN,tr|A0A7P0TBE2|A0A7P0TBE2_HUMAN,tr|A0A7P0Z4G4|A0A7P0Z4G4_HUMAN,tr|A0A7P0TAX2|A0A7P0TAX2_HUMAN,tr|A0A7P0TBK2|A0A7P0TBK2_HUMAN,tr|A0A7P0TAG1|A0A7P0TAG1_HUMAN,tr|A0A7P0TA47|A0A7P0TA47_HUMAN,tr|A0A7P0T997|A0A7P0T997_HUMAN,tr|H0YDD4|H0YDD4_HUMAN" 9 883.5127 1.46 11032 8654 2 883.511682 442.7636 "Dihydrolipoyllysine-residue acetyltransferase component of pyruvate dehydrogenase complex, mitochondrial OS=Homo sapiens OX=9606 GN=DLAT PE=1 SV=3" 6 2202.6 - 2.96E+06 - - - -1.1715 - 1.064 0.159 - 130.3 1 2 0 -0.001 8 0 0 0 1.83E+08 1.26E+08 - - - 0.4021 0.9996 221125_WJC_METTL3_EV_vs_WT_F02.08665.08665.2 0.00661 16-Oct K.LGELTGTVK.E "sp|O43615|TIM44_HUMAN,tr|M0R301|M0R301_HUMAN,tr|M0QXU7|M0QXU7_HUMAN" 3 916.5229 1.16 11036 8665 2 916.523544 459.2687 Mitochondrial import inner membrane translocase subunit TIM44 OS=Homo sapiens OX=9606 GN=TIMM44 PE=1 SV=2 6 2204.2 - 993709 - - - 0.6514 - 1.62 0.394 - 193.4 1 2 0 0.0006 9 0 0 0 6.68E+08 5.77E+08 - - - 3.3466 0.993 221125_WJC_METTL3_EV_vs_WT_F02.08666.08666.2 0.0164 16-Sep K.LGELTGTVK[136.11].E "sp|O43615|TIM44_HUMAN,tr|M0R301|M0R301_HUMAN,tr|M0QXU7|M0QXU7_HUMAN" 3 924.5371 1.16 11037 8666 2 924.540379 463.2758 Mitochondrial import inner membrane translocase subunit TIM44 OS=Homo sapiens OX=9606 GN=TIMM44 PE=1 SV=2 6 2204.2 - 1.23E+06 - - - 3.4958 - 1.573 0.266 - 166.8 1 2 0 0.0032 9 0 0 0 6.68E+08 5.77E+08 - - - 2.3152 0.9947 221125_WJC_METTL3_EV_vs_WT_F02.08680.08680.2 0.219 16-Sep R.ILQDSLGGR.T "sp|P52732|KIF11_HUMAN,tr|A0A7I2YQY4|A0A7I2YQY4_HUMAN,tr|A0A7I2V3A9|A0A7I2V3A9_HUMAN,tr|A0A7I2V3V3|A0A7I2V3V3_HUMAN" 4 957.5243 3.44 11042 8680 2 957.523248 479.7694 Kinesin-like protein KIF11 OS=Homo sapiens OX=9606 GN=KIF11 PE=1 SV=2 5.84 2206.1 - 2.64E+06 - - - -1.1446 - 1.392 0.167 - 168.1 1 2 0 -0.0011 9 0 0 0 7.71E+07 2.24E+07 - - - 1.231 0.999 221125_WJC_METTL3_EV_vs_WT_F02.08683.08683.2 0.034 16-Sep R.ILQDSLGGR[166.11].T "sp|P52732|KIF11_HUMAN,tr|A0A7I2YQY4|A0A7I2YQY4_HUMAN,tr|A0A7I2V3A9|A0A7I2V3A9_HUMAN,tr|A0A7I2V3V3|A0A7I2V3V3_HUMAN" 4 967.5326 3.84 11043 8683 2 967.531701 484.7736 Kinesin-like protein KIF11 OS=Homo sapiens OX=9606 GN=KIF11 PE=1 SV=2 5.84 2206.5 - 590683 - - - -0.9436 - 1.706 0.264 - 222.1 1 2 0 -0.0009 9 0 0 0 8.32E+07 2.17E+07 - - - 2.5359 0.9872 221125_WJC_METTL3_EV_vs_WT_F02.08693.08693.2 2.27 12-Aug R.LLQEQLR.Y "sp|Q4VCS5|AMOT_HUMAN,sp|Q9Y2J4|AMOL2_HUMAN,sp|Q8IY63|AMOL1_HUMAN,tr|D6RF61|D6RF61_HUMAN,tr|D6RFG0|D6RFG0_HUMAN,tr|D6RIC7|D6RIC7_HUMAN,tr|F8WDH4|F8WDH4_HUMAN,tr|D6RJA4|D6RJA4_HUMAN,tr|D6RCL7|D6RCL7_HUMAN,tr|D6RBK2|D6RBK2_HUMAN" 10 898.5236 0.96 11047 8693 2 898.524944 450.2691 Angiomotin OS=Homo sapiens OX=9606 GN=AMOT PE=1 SV=1 6 2207.7 - 1.56E+06 - - - 1.478 - 1.419 0.089 - 213.7 1 2 0 0.0013 7 0 0 0 1.32E+08 1.37E+08 - - - 0.8068 0.8116 221125_WJC_METTL3_EV_vs_WT_F02.08695.08695.2 0.137 12-Jul E.LYEEELR.E "sp|P17661|DESM_HUMAN,sp|P05787|K2C8_HUMAN,sp|A6NCN2|KR87P_HUMAN,sp|P78386|KRT85_HUMAN,sp|O43790|KRT86_HUMAN,sp|P78385|KRT83_HUMAN,tr|F8VUG2|F8VUG2_HUMAN,tr|F8W1U3|F8W1U3_HUMAN,tr|F5GYI5|F5GYI5_HUMAN" 9 950.4709 589.68 11049 8695 2 950.470292 476.2427 Desmin OS=Homo sapiens OX=9606 GN=DES PE=1 SV=3 4.25 2207.9 - 1.51E+06 - - - -0.6523 - 1.344 0.184 - 233.4 1 1 0 -0.0006 7 0 0 0 6.27E+07 1.06E+05 - - - 1.3366 0.9956 221125_WJC_METTL3_EV_vs_WT_F02.08705.08705.2 0.197 16-Oct K.LLQAEEVAR[166.11].L "sp|P28324|ELK4_HUMAN,tr|A0A087X2F7|A0A087X2F7_HUMAN" 2 1037.5745 1.27 11055 8705 2 1037.572886 519.7945 ETS domain-containing protein Elk-4 OS=Homo sapiens OX=9606 GN=ELK4 PE=1 SV=3 4.53 2209.1 - 306092 - - - -1.5353 - 1.437 0.197 - 378.9 1 2 0 -0.0016 9 0 0 0 1.76E+07 1.38E+07 - - - 1.5444 0.9994 221125_WJC_METTL3_EV_vs_WT_F02.08720.08720.2 0.0146 14-Jun R.LTPEELER.A "sp|O95399|UTS2_HUMAN,sp|P11021|BIP_HUMAN,tr|A0A7P0TB36|A0A7P0TB36_HUMAN,tr|A0A7P0TAI0|A0A7P0TAI0_HUMAN,tr|Q5H8X8|Q5H8X8_HUMAN" 5 985.508 0.61 11061 8720 2 985.50822 493.7613 Urotensin-2 OS=Homo sapiens OX=9606 GN=UTS2 PE=1 SV=1 4.25 2211.1 - 420792 - - - 0.1969 - 1.36 0.382 - 173.6 1 2 0 0.0002 8 0 0 0 2.16E+08 3.55E+08 - - - 2.7898 0.9705 221125_WJC_METTL3_EV_vs_WT_F02.08729.08729.2 0.295 12-Apr R.LNLVGEK[136.11].L "sp|Q96EY4|TMA16_HUMAN,tr|H0Y9X1|H0Y9X1_HUMAN,tr|D6RC31|D6RC31_HUMAN,tr|D6RE67|D6RE67_HUMAN,tr|D6RA57|D6RA57_HUMAN" 5 779.4633 0.26 11066 8729 2 779.462924 390.7389 Translation machinery-associated protein 16 OS=Homo sapiens OX=9606 GN=TMA16 PE=1 SV=2 6 2212.1 - 3.24E+06 - - - -0.4234 - 1.29 0.082 - 45.1 16 2 0 -0.0003 7 0 0 0 7.95E+07 3.02E+08 - - - -0.0845 0.9868 221125_WJC_METTL3_EV_vs_WT_F02.08731.08731.2 0.767 14-Jul K.LLNPSLQK[136.11].V sp|Q9HAV4|XPO5_HUMAN 1 919.5582 0.77 11068 8731 2 919.558567 460.7864 Exportin-5 OS=Homo sapiens OX=9606 GN=XPO5 PE=1 SV=1 8.75 2212.3 - 2.88E+06 - - - 0.3806 - 1.241 0.105 - 83.8 1 2 0 0.0003 8 0 0 0 3.35E+07 4.38E+07 - - - 0.4676 0.9991 221125_WJC_METTL3_EV_vs_WT_F02.08739.08739.2 0.16 12-Sep R.TLTPLGR[166.11].E sp|Q96HS1|PGAM5_HUMAN 1 766.4577 0.02 11073 8739 2 766.458063 384.2361 "Serine\threonine-protein phosphatase PGAM5, mitochondrial OS=Homo sapiens OX=9606 GN=PGAM5 PE=1 SV=2" 9.41 2213.3 - 6.06E+06 - - - 0.5284 - 1.488 0.301 - 335.2 1 2 0 0.0004 7 0 0 0 5.00E+06 2.09E+08 - - - 2.5233 0.999 221125_WJC_METTL3_EV_vs_WT_F02.08742.08742.2 0.0435 14-Jul R.LTPEELER[166.11].A "sp|O95399|UTS2_HUMAN,sp|P11021|BIP_HUMAN,tr|A0A7P0TB36|A0A7P0TB36_HUMAN,tr|A0A7P0TAI0|A0A7P0TAI0_HUMAN,tr|Q5H8X8|Q5H8X8_HUMAN" 5 995.5163 0.61 11075 8742 2 995.517073 498.7654 Urotensin-2 OS=Homo sapiens OX=9606 GN=UTS2 PE=1 SV=1 4.25 2213.6 - 1.58E+06 - - - 0.7805 - 1.399 0.342 - 272.7 1 2 0 0.0008 8 0 0 0 2.16E+08 3.55E+08 - - - 2.5794 0.8027 221125_WJC_METTL3_EV_vs_WT_F02.08745.08745.2 2.52 16-Apr K.GPDTLC[160.03]FDK[136.11].D "sp|Q14746|COG2_HUMAN,tr|V9GY21|V9GY21_HUMAN" 2 1059.4786 0.19 11076 8745 2 1059.477863 530.7466 Conserved oligomeric Golgi complex subunit 2 OS=Homo sapiens OX=9606 GN=COG2 PE=1 SV=1 4.21 2214 - 127207 - - - -0.739 - 0.883 0.016 - 62.2 2 2 0 -0.0008 9 0 0 0 2.54E+06 1.31E+07 - - - -1.3355 0.9964 221125_WJC_METTL3_EV_vs_WT_F02.08747.08747.2 0.269 12-Jun R.IIGDPYK[136.11].V "sp|Q92945|FUBP2_HUMAN,tr|M0R0I5|M0R0I5_HUMAN,tr|M0QYH3|M0QYH3_HUMAN,tr|M0R0C6|M0R0C6_HUMAN,tr|A0A087WTP3|A0A087WTP3_HUMAN" 5 812.4524 0.78 11077 8747 2 812.452673 407.2335 Far upstream element-binding protein 2 OS=Homo sapiens OX=9606 GN=KHSRP PE=1 SV=4 5.83 2214.2 - 4.73E+06 - - - 0.3914 - 1.072 0.287 - 90.2 1 2 0 0.0003 7 0 0 0 2.56E+08 3.28E+08 - - - 1.381 0.9982 221125_WJC_METTL3_EV_vs_WT_F02.08751.08751.2 0.203 14-Aug K.ASVLLGSR.G "sp|Q8N1F7|NUP93_HUMAN,tr|H3BM93|H3BM93_HUMAN,tr|H3BV11|H3BV11_HUMAN,tr|H3BRI8|H3BRI8_HUMAN,tr|H3BNN5|H3BNN5_HUMAN,tr|H3BVG0|H3BVG0_HUMAN" 6 801.4709 1.58 11078 8751 2 801.471548 401.7427 Nuclear pore complex protein Nup93 OS=Homo sapiens OX=9606 GN=NUP93 PE=1 SV=2 9.79 2214.8 - 5.33E+06 - - - 0.8684 - 1.759 0.176 - 265.2 1 2 0 0.0007 8 0 0 0 1.80E+08 1.14E+08 - - - 2.044 0.998 221125_WJC_METTL3_EV_vs_WT_F02.08760.08760.2 1.96 16-Sep K.LLEAMGTSK[136.11].K "sp|Q9Y421|FA32A_HUMAN,tr|K7ENN5|K7ENN5_HUMAN,tr|K7EIY1|K7EIY1_HUMAN,tr|K7ELZ8|K7ELZ8_HUMAN" 4 956.5092 1.91 11081 8760 2 956.510941 479.2619 Protein FAM32A OS=Homo sapiens OX=9606 GN=FAM32A PE=1 SV=2 6 2216.2 - 680593 - - - 1.8013 - 1.609 0.269 - 205.7 1 2 0 0.0017 9 0 0 0 6.01E+07 3.15E+07 - - - 2.4033 0.9991 221125_WJC_METTL3_EV_vs_WT_F02.08764.08764.2 0.0257 12-Jul R.LGMDGYR.G "sp|P61626|LYSC_HUMAN,tr|A0A0B4J259|A0A0B4J259_HUMAN,tr|F8VV32|F8VV32_HUMAN" 3 810.3694 804.02 11083 8764 2 810.370548 406.192 Lysozyme C OS=Homo sapiens OX=9606 GN=LYZ PE=1 SV=1 5.84 2216.8 - 5.63E+06 - - - 1.387 - 1.505 0.349 - 142.3 1 2 0 0.0011 7 0 0 0 2.54E+08 3.16E+05 - - - 2.9136 0.8923 221125_WJC_METTL3_EV_vs_WT_F02.08766.08766.2 3.18 12-Jun K.FYVGHDP.- "sp|P56556|NDUA6_HUMAN,tr|R4GN43|R4GN43_HUMAN,tr|A0A2Y9D025|A0A2Y9D025_HUMAN" 3 833.3708 - 11085 8766 2 833.37129 417.6927 NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 6 OS=Homo sapiens OX=9606 GN=NDUFA6 PE=1 SV=4 5.08 2217 - 3.24E+06 - - - 0.5832 - 0.892 0.06 - 78.8 1 2 0 0.0005 7 0 0 0 - - - - - -0.8781 0.7697 221125_WJC_METTL3_EV_vs_WT_F02.08767.08767.2 0.00257 14-Aug Q.AAILMGDK[136.11].S "sp|P0DMV8|HS71A_HUMAN,sp|P34931|HS71L_HUMAN,sp|P0DMV9|HS71B_HUMAN,tr|Q53FA3|Q53FA3_HUMAN,tr|V9GZ37|V9GZ37_HUMAN,tr|A0A0G2JIW1|A0A0G2JIW1_HUMAN" 6 825.451 0.65 11086 8767 2 825.4513 413.7328 Heat shock 70 kDa protein 1A OS=Homo sapiens OX=9606 GN=HSPA1A PE=1 SV=1 5.88 2217 - 2.87E+06 - - - 0.3937 - 1.599 0.094 - 203.8 1 1 0 0.0003 8 0 0 0 7.50E+07 1.16E+08 - - - 1.1508 0.9776 221125_WJC_METTL3_EV_vs_WT_F02.08768.08768.2 1 12-Aug K.LAQFVAR[166.11].N "sp|Q8IWX8|CHERP_HUMAN,tr|J3QK89|J3QK89_HUMAN" 2 813.4736 1.21 11087 8768 2 813.476489 407.7441 Calcium homeostasis endoplasmic reticulum protein OS=Homo sapiens OX=9606 GN=CHERP PE=1 SV=3 9.75 2217.1 - 2.64E+06 - - - 3.4986 - 1.645 0.102 - 183.3 1 2 0 0.0028 7 0 0 0 1.31E+08 1.09E+08 - - - 1.3706 0.9913 221125_WJC_METTL3_EV_vs_WT_F02.08773.08773.2 0.157 14-Jul R.IFEPPPPK[136.11].K sp|O43143|DHX15_HUMAN 1 931.5259 0.49 11089 8773 2 931.525358 466.7702 Pre-mRNA-splicing factor ATP-dependent RNA helicase DHX15 OS=Homo sapiens OX=9606 GN=DHX15 PE=1 SV=2 6 2217.7 - 633251 - - - -0.5325 - 1.389 0.095 - 120.2 1 2 0 -0.0005 8 0 0 0 1.68E+07 3.45E+07 - - - 0.7335 0.9923 221125_WJC_METTL3_EV_vs_WT_F02.08784.08784.2 2 16-Jun R.VPPPPPIAR.A "sp|P07910|HNRPC_HUMAN,tr|B4DY08|B4DY08_HUMAN,tr|G3V575|G3V575_HUMAN,tr|G3V5V7|G3V5V7_HUMAN,tr|B2R5W2|B2R5W2_HUMAN,tr|G3V4C1|G3V4C1_HUMAN,tr|G3V576|G3V576_HUMAN,tr|G3V2D6|G3V2D6_HUMAN,tr|G3V4W0|G3V4W0_HUMAN,tr|G3V555|G3V555_HUMAN,tr|G3V2Q1|G3V2Q1_HUMAN" 11 942.5651 1.82 11095 8784 2 942.565434 472.2898 Heterogeneous nuclear ribonucleoproteins C1\C2 OS=Homo sapiens OX=9606 GN=HNRNPC PE=1 SV=4 9.72 2219.1 - 2.06E+06 - - - 0.3681 - 1.179 0.178 - 128 1 2 0 0.0003 9 0 0 0 4.76E+08 2.61E+08 - - - 0.832 0.9898 221125_WJC_METTL3_EV_vs_WT_F02.08787.08787.2 2.13 16-Jun K.VIPTEC[160.03]AIK.V "sp|O14730|RIOK3_HUMAN,tr|J3QQL5|J3QQL5_HUMAN,tr|B4E1Q4|B4E1Q4_HUMAN" 3 1029.5529 0.28 11097 8787 2 1029.55279 515.7837 Serine\threonine-protein kinase RIO3 OS=Homo sapiens OX=9606 GN=RIOK3 PE=1 SV=2 5.97 2219.5 - 188757 - - - -0.0758 - 1.03 0.2 - 113.1 1 2 0 -0.0001 9 0 0 0 6.51E+06 2.31E+07 - - - 0.6037 0.9983 221125_WJC_METTL3_EV_vs_WT_F02.08790.08790.2 0.0891 12-May R.VMEYINR[166.11].L "sp|Q00610|CLH1_HUMAN,tr|A0A087WVQ6|A0A087WVQ6_HUMAN" 2 933.4618 0.84 11098 8790 2 933.461735 467.7382 Clathrin heavy chain 1 OS=Homo sapiens OX=9606 GN=CLTC PE=1 SV=5 5.97 2219.9 - 904877 - - - -0.0246 - 1.284 0.282 - 87 1 2 0 0 7 0 0 0 7.36E+07 8.78E+07 - - - 1.9159 0.9962 221125_WJC_METTL3_EV_vs_WT_F02.08792.08792.2 0.18 16-May R.VPPPPPIAR[166.11].A "sp|P07910|HNRPC_HUMAN,tr|B4DY08|B4DY08_HUMAN,tr|G3V575|G3V575_HUMAN,tr|G3V5V7|G3V5V7_HUMAN,tr|B2R5W2|B2R5W2_HUMAN,tr|G3V4C1|G3V4C1_HUMAN,tr|G3V576|G3V576_HUMAN,tr|G3V2D6|G3V2D6_HUMAN,tr|G3V4W0|G3V4W0_HUMAN,tr|G3V555|G3V555_HUMAN,tr|G3V2Q1|G3V2Q1_HUMAN" 11 952.5734 1.81 11099 8792 2 952.573931 477.294 Heterogeneous nuclear ribonucleoproteins C1\C2 OS=Homo sapiens OX=9606 GN=HNRNPC PE=1 SV=4 9.72 2220.1 - 1.23E+06 - - - 0.6026 - 1.191 0.25 - 89.9 1 2 0 0.0006 9 0 0 0 5.37E+08 2.97E+08 - - - 1.393 0.8848 221125_WJC_METTL3_EV_vs_WT_F02.08798.08798.2 0.404 12-Sep L.LQALLEK[136.11].E "sp|Q9BT92|TCHP_HUMAN,sp|O95429|BAG4_HUMAN,sp|Q9H2M9|RBGPR_HUMAN" 3 821.5102 0.19 11102 8798 2 821.509694 411.7624 Trichoplein keratin filament-binding protein OS=Homo sapiens OX=9606 GN=TCHP PE=1 SV=1 6 2220.9 - 1.88E+06 - - - -0.6208 - 2.049 0.062 - 221.2 1 1 0 -0.0005 7 0 0 0 1.34E+07 7.22E+07 - - - 1.7717 0.9997 221125_WJC_METTL3_EV_vs_WT_F02.08799.08799.2 0.0361 18-Oct R.FGGALDAAAK[136.11].M sp|P53396|ACLY_HUMAN 1 927.4905 0.55 11103 8799 2 927.491325 464.7525 ATP-citrate synthase OS=Homo sapiens OX=9606 GN=ACLY PE=1 SV=3 5.84 2220.9 - 1.19E+06 - - - 0.8561 - 2.003 0.413 - 191.7 1 2 0 0.0008 10 0 0 0 3.36E+07 6.15E+07 - - - 4.0301 0.997 221125_WJC_METTL3_EV_vs_WT_F02.08807.08807.2 0.134 12-Jul K.LVEQAFR[166.11].K "sp|P85037|FOXK1_HUMAN,sp|Q9NV79|PCMD2_HUMAN,tr|F8W9F3|F8W9F3_HUMAN,tr|V9GYZ7|V9GYZ7_HUMAN,tr|V9GZ41|V9GZ41_HUMAN,tr|V9GYL1|V9GYL1_HUMAN" 6 871.4791 0.93 11107 8807 2 871.479318 436.7468 Forkhead box protein K1 OS=Homo sapiens OX=9606 GN=FOXK1 PE=1 SV=1 6 2221.9 - 1.60E+06 - - - 0.2249 - 1.472 0.166 - 150 1 2 0 0.0002 7 0 0 0 7.60E+07 8.16E+07 - - - 1.492 0.9994 221125_WJC_METTL3_EV_vs_WT_F02.08808.08808.2 0.00309 12-Aug K.MADIEYR[166.11].L sp|P40937|RFC5_HUMAN 1 906.4145 0.91 11108 8808 2 906.413858 454.2145 Replication factor C subunit 5 OS=Homo sapiens OX=9606 GN=RFC5 PE=1 SV=1 4.37 2222.1 - 290543 - - - -0.6785 - 1.443 0.359 - 257.7 1 2 0 -0.0006 7 0 0 0 1.03E+07 1.13E+07 - - - 2.8544 0.996 221125_WJC_METTL3_EV_vs_WT_F02.08818.08818.2 1.02 12-Jul R.VMEYINR.L "sp|Q00610|CLH1_HUMAN,tr|A0A087WVQ6|A0A087WVQ6_HUMAN" 2 923.4535 0.84 11114 8818 2 923.452722 462.734 Clathrin heavy chain 1 OS=Homo sapiens OX=9606 GN=CLTC PE=1 SV=5 5.97 2223.2 - 2.14E+06 - - - -0.8295 - 1.212 0.23 - 167.4 1 2 0 -0.0008 7 0 0 0 7.36E+07 8.78E+07 - - - 1.3488 0.9979 221125_WJC_METTL3_EV_vs_WT_F02.08819.08819.2 0.042 12-Jul R.GVVMLNR.V "sp|P18031|PTN1_HUMAN,tr|B4DSN5|B4DSN5_HUMAN" 2 787.4374 1.21 11115 8819 2 787.43785 394.726 Tyrosine-protein phosphatase non-receptor type 1 OS=Homo sapiens OX=9606 GN=PTPN1 PE=1 SV=1 9.75 2223.3 - 1.23E+06 - - - 0.5156 - 1.513 0.201 - 240.9 1 2 0 0.0004 7 0 0 0 4.20E+07 3.46E+07 - - - 1.8375 0.9809 221125_WJC_METTL3_EV_vs_WT_F02.08820.08820.2 3.42 12-Jun R.FAGYIEK[136.11].V "sp|P07197|NFM_HUMAN,tr|E7ESP9|E7ESP9_HUMAN,tr|E7EMV2|E7EMV2_HUMAN" 3 834.4367 2.33 11116 8820 2 834.436041 418.2256 Neurofilament medium polypeptide OS=Homo sapiens OX=9606 GN=NEFM PE=1 SV=3 6 2223.3 - 3.10E+06 - - - -0.7957 - 1.106 0.121 - 68 1 2 0 -0.0007 7 0 0 0 3.59E+08 1.54E+08 - - - 0.2537 0.9987 221125_WJC_METTL3_EV_vs_WT_F02.08830.08830.2 0.0201 12-Jul K.IGYLNDR.V "sp|Q9H0P0|5NT3A_HUMAN,tr|X6RM59|X6RM59_HUMAN" 2 849.4345 3.34 11119 8830 2 849.434005 425.7245 Cytosolic 5'-nucleotidase 3A OS=Homo sapiens OX=9606 GN=NT5C3A PE=1 SV=3 5.84 2224.8 - 476403 - - - -0.5439 - 1.354 0.29 - 150.6 1 2 0 -0.0005 7 0 0 0 3.19E+08 9.54E+07 - - - 2.1431 0.9964 221125_WJC_METTL3_EV_vs_WT_F02.08842.08842.2 0.013 12-Aug K.LVEQAFR.K "sp|P85037|FOXK1_HUMAN,sp|Q9NV79|PCMD2_HUMAN,tr|F8W9F3|F8W9F3_HUMAN,tr|V9GYZ7|V9GYZ7_HUMAN,tr|V9GZ41|V9GZ41_HUMAN,tr|V9GYL1|V9GYL1_HUMAN" 6 861.4709 0.93 11124 8842 2 861.47065 431.7427 Forkhead box protein K1 OS=Homo sapiens OX=9606 GN=FOXK1 PE=1 SV=1 6 2226.5 - 2.06E+06 - - - -0.2345 - 1.579 0.115 - 208 1 2 0 -0.0002 7 0 0 0 7.55E+07 8.16E+07 - - - 1.3377 0.9975 221125_WJC_METTL3_EV_vs_WT_F02.08852.08852.2 0.0955 16-Sep K.ILNDDTALK[136.11].E "sp|P54727|RD23B_HUMAN,tr|Q5W0S4|Q5W0S4_HUMAN,tr|Q5W0S5|Q5W0S5_HUMAN" 3 1009.5535 1.44 11128 8852 2 1009.553456 505.784 UV excision repair protein RAD23 homolog B OS=Homo sapiens OX=9606 GN=RAD23B PE=1 SV=1 4.21 2227.8 - 309507 - - - -0.0693 - 1.383 0.223 - 177.6 1 2 0 -0.0001 9 0 0 0 4.89E+07 3.40E+07 - - - 1.6261 0.86 221125_WJC_METTL3_EV_vs_WT_F02.08858.08858.2 0.131 12-Jul K.AAC[160.03]LLPK.L "sp|P02768|ALBU_HUMAN,tr|B7WNR0|B7WNR0_HUMAN,tr|H0YA55|H0YA55_HUMAN,tr|A0A0C4DGB6|A0A0C4DGB6_HUMAN,tr|D6RHD5|D6RHD5_HUMAN" 5 771.4313 2.19 11131 8858 2 772.434364 386.7229 Albumin OS=Homo sapiens OX=9606 GN=ALB PE=1 SV=2 8.27 2228.4 - 1.84E+06 - - - 1300.2687 - 1.542 0.16 - 148.7 1 2 0 1.0031 7 0 0 0 2.21E+08 1.01E+08 - - - 1.28 0.9673 221125_WJC_METTL3_EV_vs_WT_F02.08861.08861.2 0.576 12-Jun K.YLGEPIK.S sp|Q8IW92|GLBL2_HUMAN 1 818.4538 0.25 11132 8861 2 818.455059 410.2342 Beta-galactosidase-1-like protein 2 OS=Homo sapiens OX=9606 GN=GLB1L2 PE=1 SV=1 6 2228.8 - 426140 - - - 1.5322 - 1.113 0.11 - 110.2 1 2 0 0.0013 7 0 0 0 2.11E+07 8.29E+07 - - - 0.1923 0.9774 221125_WJC_METTL3_EV_vs_WT_F02.08863.08863.2 0.00244 22-Sep Y.GPVAAAAVAAAR.G "sp|Q96DH6|MSI2H_HUMAN,tr|B4DHE8|B4DHE8_HUMAN,tr|A0A6Q8PF05|A0A6Q8PF05_HUMAN,tr|A0A6Q8PH51|A0A6Q8PH51_HUMAN,tr|B4DM51|B4DM51_HUMAN,tr|A0A6Q8PH26|A0A6Q8PH26_HUMAN" 6 1023.5825 1.61 11133 8863 2 1023.581934 512.7985 RNA-binding protein Musashi homolog 2 OS=Homo sapiens OX=9606 GN=MSI2 PE=1 SV=1 9.75 2229 - 146045 - - - -0.5803 - 1.77 0.379 - 194.5 1 1 0 -0.0006 12 0 0 0 6.90E+06 4.28E+06 - - - 3.3425 0.9981 221125_WJC_METTL3_EV_vs_WT_F02.08869.08869.2 0.576 12-Jul K.NIQVVVR[166.11].C "sp|P52732|KIF11_HUMAN,tr|A0A7I2YQY4|A0A7I2YQY4_HUMAN,tr|A0A7I2V3V3|A0A7I2V3V3_HUMAN" 3 836.5108 5.12 11137 8869 2 836.510909 419.2627 Kinesin-like protein KIF11 OS=Homo sapiens OX=9606 GN=KIF11 PE=1 SV=2 9.75 2229.7 - 2.01E+06 - - - 0.1817 - 1.404 0.235 - 162.3 1 2 0 0.0002 7 0 0 0 6.25E+08 1.22E+08 - - - 1.8518 0.975 221125_WJC_METTL3_EV_vs_WT_F02.08879.08879.2 2.93 16-May K.SAAFEDEAK[136.11].Y "sp|Q8WZ42|TITIN_HUMAN,tr|A0A0A0MTS7|A0A0A0MTS7_HUMAN,tr|A0A0A0MRA3|A0A0A0MRA3_HUMAN" 3 974.4436 0 11141 8879 2 974.44464 488.2291 Titin OS=Homo sapiens OX=9606 GN=TTN PE=1 SV=4 4.14 2231.1 - 421594 - - - 1.0252 - 1.087 0.124 - 80.2 1 2 0 0.001 9 0 0 0 9.85E+04 2.61E+07 - - - 0.1979 0.985 221125_WJC_METTL3_EV_vs_WT_F02.08881.08881.2 0.421 14-May R.QYVQGC[160.03]GV.- sp|P61626|LYSC_HUMAN 1 909.4015 - 11142 8881 2 909.402896 455.708 Lysozyme C OS=Homo sapiens OX=9606 GN=LYZ PE=1 SV=1 5.52 2231.3 - 321334 - - - 1.5879 - 0.952 0.25 - 76.1 1 2 0 0.0014 8 0 0 0 - - - - - 0.7387 0.9996 221125_WJC_METTL3_EV_vs_WT_F02.08890.08890.2 0.1 14-Sep K.IEAVYVSR[166.11].R "sp|Q96T37|RBM15_HUMAN,tr|A0A494C001|A0A494C001_HUMAN,tr|A0A499FJY3|A0A499FJY3_HUMAN,tr|A0A087WWP4|A0A087WWP4_HUMAN" 4 945.5159 1.09 11143 8890 2 945.516598 473.7652 RNA-binding protein 15 OS=Homo sapiens OX=9606 GN=RBM15 PE=1 SV=2 6 2232.9 - 1.22E+06 - - - 0.7361 - 1.935 0.342 - 291.7 1 2 0 0.0007 8 0 0 0 7.40E+07 6.81E+07 - - - 3.5576 0.9991 221125_WJC_METTL3_EV_vs_WT_F02.08891.08891.2 0.113 14-Sep K.IEAVYVSR.R "sp|Q96T37|RBM15_HUMAN,tr|A0A494C001|A0A494C001_HUMAN,tr|A0A499FJY3|A0A499FJY3_HUMAN,tr|A0A087WWP4|A0A087WWP4_HUMAN" 4 935.5076 1.09 11144 8891 2 935.507949 468.7611 RNA-binding protein 15 OS=Homo sapiens OX=9606 GN=RBM15 PE=1 SV=2 6 2232.9 - 975903 - - - 0.3389 - 1.638 0.267 - 267.5 1 2 0 0.0003 8 0 0 0 7.41E+07 6.81E+07 - - - 2.5013 0.9981 221125_WJC_METTL3_EV_vs_WT_F02.08902.08902.2 0.0185 12-Jun R.AC[160.03]YGVLR[166.11].F "sp|P23396|RS3_HUMAN,tr|H0YEU2|H0YEU2_HUMAN,tr|E9PL09|E9PL09_HUMAN" 3 847.425 0.56 11151 8902 2 847.424889 424.7198 40S ribosomal protein S3 OS=Homo sapiens OX=9606 GN=RPS3 PE=1 SV=2 8.27 2234.2 - 1.43E+06 - - - -0.105 - 1.282 0.273 - 213.3 1 2 0 -0.0001 7 0 0 0 1.82E+08 3.23E+08 - - - 1.8445 0.9987 221125_WJC_METTL3_EV_vs_WT_F02.08906.08906.2 0.0881 12-Jun K.IMEYYEK[136.11].K "sp|P36543|VATE1_HUMAN,sp|Q96A05|VATE2_HUMAN,tr|C9J8H1|C9J8H1_HUMAN" 3 982.4561 1.52 11153 8906 2 982.456619 492.2353 V-type proton ATPase subunit E 1 OS=Homo sapiens OX=9606 GN=ATP6V1E1 PE=1 SV=1 4.53 2234.7 - 269764 - - - 0.5079 - 1.168 0.367 - 94.5 1 2 0 0.0005 7 0 0 0 2.71E+07 1.78E+07 - - - 2.2436 0.9973 221125_WJC_METTL3_EV_vs_WT_F02.08915.08915.2 0.000588 16-Jul R.VVTMEVEAR[166.11].N "sp|Q99829|CPNE1_HUMAN,tr|B0QZ18|B0QZ18_HUMAN,tr|F2Z2V0|F2Z2V0_HUMAN,tr|Q5JX56|Q5JX56_HUMAN,tr|A6PVH9|A6PVH9_HUMAN,tr|Q5JX59|Q5JX59_HUMAN,tr|Q5JX58|Q5JX58_HUMAN,tr|E7ENH5|E7ENH5_HUMAN,tr|Q5JX55|Q5JX55_HUMAN,tr|Q5JX60|Q5JX60_HUMAN,tr|Q5JX44|Q5JX44_HUMAN" 11 1042.5357 0.47 11158 8915 2 1042.532727 522.2751 Copine-1 OS=Homo sapiens OX=9606 GN=CPNE1 PE=1 SV=1 4.53 2235.9 - 54718 - - - -2.8047 - 1.568 0.321 - 115.7 1 2 0 -0.0029 9 0 0 0 6.94E+06 1.47E+07 - - - 2.7123 0.9983 221125_WJC_METTL3_EV_vs_WT_F02.08919.08919.2 0.273 14-Aug R.YVLC[160.03]TAPR[166.11].A "sp|P25205|MCM3_HUMAN,tr|J3KQ69|J3KQ69_HUMAN,tr|A0A499FHX9|A0A499FHX9_HUMAN" 3 988.504 0.24 11159 8919 2 988.505599 495.2593 DNA replication licensing factor MCM3 OS=Homo sapiens OX=9606 GN=MCM3 PE=1 SV=3 8.22 2236.5 - 1.25E+06 - - - 1.6611 - 1.442 0.314 - 242.8 1 2 0 0.0016 8 0 0 0 2.58E+07 1.05E+08 - - - 2.4636 0.8701 221125_WJC_METTL3_EV_vs_WT_F02.08929.08929.2 0.112 14-Jul A.PSGLPSER.K sp|Q8N201|INT1_HUMAN 1 841.4294 0.69 11163 8929 2 841.429857 421.722 Integrator complex subunit 1 OS=Homo sapiens OX=9606 GN=INTS1 PE=1 SV=2 6.43 2237.7 - 2.63E+06 - - - 0.5657 - 1.472 0.203 - 287.4 1 1 0 0.0005 8 0 0 0 2.13E+08 3.08E+08 - - - 1.7062 0.9991 221125_WJC_METTL3_EV_vs_WT_F02.08943.08943.2 0.00859 18-Sep R.LLSTDPVAAK.E "sp|Q10567|AP1B1_HUMAN,tr|C9J1E7|C9J1E7_HUMAN" 2 1013.5757 0.94 11171 8943 2 1013.575265 507.7951 AP-1 complex subunit beta-1 OS=Homo sapiens OX=9606 GN=AP1B1 PE=1 SV=2 5.84 2239.4 - 1.01E+06 - - - -0.44 - 1.722 0.261 - 209.1 1 2 0 -0.0004 10 0 0 0 7.26E+07 7.76E+07 - - - 2.4856 0.9989 221125_WJC_METTL3_EV_vs_WT_F02.08952.08952.2 0.534 18-Aug R.LLSTDPVAAK[136.11].E "sp|Q10567|AP1B1_HUMAN,tr|C9J1E7|C9J1E7_HUMAN" 2 1021.5899 0.94 11175 8952 2 1021.590186 511.8022 AP-1 complex subunit beta-1 OS=Homo sapiens OX=9606 GN=AP1B1 PE=1 SV=2 5.84 2240.5 - 1.60E+06 - - - 0.2692 - 1.543 0.274 - 141 1 2 0 0.0003 10 0 0 0 7.26E+07 7.76E+07 - - - 2.2753 0.9974 221125_WJC_METTL3_EV_vs_WT_F02.08956.08956.2 0.441 12-Jun K.LDDTYIK[136.11].A "sp|Q99615|DNJC7_HUMAN,tr|A0A6I8PRZ0|A0A6I8PRZ0_HUMAN,tr|A0A6I8PLE7|A0A6I8PLE7_HUMAN,tr|A0A6I8PR89|A0A6I8PR89_HUMAN,tr|A0A6I8PIK4|A0A6I8PIK4_HUMAN,tr|A0A6I8PUC2|A0A6I8PUC2_HUMAN,tr|A0A6I8PS32|A0A6I8PS32_HUMAN,tr|A0A6I8PUD4|A0A6I8PUD4_HUMAN,tr|A0A6I8PU73|A0A6I8PU73_HUMAN,tr|A0A6I8PU89|A0A6I8PU89_HUMAN" 10 874.4527 0.49 11178 8956 2 874.453579 438.2337 DnaJ homolog subfamily C member 7 OS=Homo sapiens OX=9606 GN=DNAJC7 PE=1 SV=2 4.21 2240.9 - 3.15E+06 - - - 0.9492 - 1.413 0.224 - 83.1 1 2 0 0.0008 7 0 0 0 1.17E+08 2.40E+08 - - - 1.7906 0.9937 221125_WJC_METTL3_EV_vs_WT_F02.08962.08962.2 0.0165 14-Aug K.LASVPEYR.Y sp|P85037|FOXK1_HUMAN 1 933.492 1.6 11180 8962 2 933.489174 467.7533 Forkhead box protein K1 OS=Homo sapiens OX=9606 GN=FOXK1 PE=1 SV=1 6 2241.7 - 404487 - - - -3.0081 - 1.633 0.211 - 199.2 1 2 0 -0.0028 8 0 0 0 8.28E+07 5.17E+07 - - - 2.0776 0.9935 221125_WJC_METTL3_EV_vs_WT_F02.08964.08964.2 0.29 12-Jul R.FEGLTAR.G sp|Q15208|STK38_HUMAN 1 792.413 3.47 11181 8964 2 792.413955 397.2138 Serine\threonine-protein kinase 38 OS=Homo sapiens OX=9606 GN=STK38 PE=1 SV=1 6 2242 - 1.68E+07 - - - 1.2014 - 1.423 0.139 - 154.2 1 2 0 0.001 7 0 0 0 9.23E+08 2.66E+08 - - - 1.1851 0.9725 221125_WJC_METTL3_EV_vs_WT_F02.08967.08967.2 0.714 12-Jul R.FEGLTAR[166.11].G sp|Q15208|STK38_HUMAN 1 802.4213 3.49 11182 8967 2 802.422706 402.2179 Serine\threonine-protein kinase 38 OS=Homo sapiens OX=9606 GN=STK38 PE=1 SV=1 6 2242.4 - 6.06E+06 - - - 1.7858 - 1.23 0.096 - 150 1 2 0 0.0014 7 0 0 0 9.21E+08 2.64E+08 - - - 0.4055 0.9819 221125_WJC_METTL3_EV_vs_WT_F02.08969.08969.2 1.1 12-Jun K.LDDTYIK.A "sp|Q99615|DNJC7_HUMAN,tr|A0A6I8PRZ0|A0A6I8PRZ0_HUMAN,tr|A0A6I8PLE7|A0A6I8PLE7_HUMAN,tr|A0A6I8PR89|A0A6I8PR89_HUMAN,tr|A0A6I8PIK4|A0A6I8PIK4_HUMAN,tr|A0A6I8PUC2|A0A6I8PUC2_HUMAN,tr|A0A6I8PS32|A0A6I8PS32_HUMAN,tr|A0A6I8PUD4|A0A6I8PUD4_HUMAN,tr|A0A6I8PU73|A0A6I8PU73_HUMAN,tr|A0A6I8PU89|A0A6I8PU89_HUMAN" 10 866.4385 0.49 11183 8969 2 866.437627 434.2266 DnaJ homolog subfamily C member 7 OS=Homo sapiens OX=9606 GN=DNAJC7 PE=1 SV=2 4.21 2242.6 - 2.61E+06 - - - -1.0641 - 1.256 0.099 - 86.4 2 2 0 -0.0009 7 0 0 0 1.18E+08 2.40E+08 - - - 0.3597 0.9667 221125_WJC_METTL3_EV_vs_WT_F02.08971.08971.2 0.726 14-Jun K.YVDPVISK[136.11].R "sp|Q14244|MAP7_HUMAN,tr|A0A087WZ40|A0A087WZ40_HUMAN" 2 927.5157 1.08 11184 8971 2 927.514705 464.7651 Ensconsin OS=Homo sapiens OX=9606 GN=MAP7 PE=1 SV=1 5.83 2242.8 - 410741 - - - -1.0555 - 1.047 0.105 - 87.4 1 2 0 -0.001 8 0 0 0 9.56E+07 8.84E+07 - - - -0.0453 0.9964 221125_WJC_METTL3_EV_vs_WT_F02.08973.08973.2 0.324 12-Aug K.IPENIYR.G "sp|P42704|LPPRC_HUMAN,tr|A0A804HI14|A0A804HI14_HUMAN,tr|A0A804HL40|A0A804HL40_HUMAN,tr|A0A804HKJ0|A0A804HKJ0_HUMAN,tr|A0A804HKR3|A0A804HKR3_HUMAN,tr|A0A804HIN4|A0A804HIN4_HUMAN,tr|A0A804HLG8|A0A804HLG8_HUMAN,tr|A0A804HIV5|A0A804HIV5_HUMAN,tr|A0A804HHY9|A0A804HHY9_HUMAN,tr|A0A804HJH8|A0A804HJH8_HUMAN,tr|B8ZZ38|B8ZZ38_HUMAN,tr|A0A804HI40|A0A804HI40_HUMAN,tr|A0A804HJZ1|A0A804HJZ1_HUMAN,tr|C9JCA9|C9JCA9_HUMAN,tr|A0A804HIQ7|A0A804HIQ7_HUMAN,tr|A0A804HK30|A0A804HK30_HUMAN,tr|A0A804HKI2|A0A804HKI2_HUMAN,tr|A0A804HJI0|A0A804HJI0_HUMAN,tr|A0A804HIG4|A0A804HIG4_HUMAN,tr|A0A804HK02|A0A804HK02_HUMAN" 20 903.4814 0.65 11185 8973 2 903.480537 452.748 "Leucine-rich PPR motif-containing protein, mitochondrial OS=Homo sapiens OX=9606 GN=LRPPRC PE=1 SV=3" 6 2243 - 649706 - - - -0.974 - 1.367 0.194 - 173.9 1 2 0 -0.0009 7 0 0 0 7.41E+07 1.14E+08 - - - 1.4642 0.9875 221125_WJC_METTL3_EV_vs_WT_F02.08983.08983.2 0.393 16-Jun R.VVEEPYTVR[166.11].E "sp|O75153|CLU_HUMAN,tr|A0A494C0R8|A0A494C0R8_HUMAN,tr|I3L2B0|I3L2B0_HUMAN,tr|I3L318|I3L318_HUMAN,tr|K7EIG1|K7EIG1_HUMAN" 5 1100.5741 7.33 11190 8983 2 1100.575745 551.2943 Clustered mitochondria protein homolog OS=Homo sapiens OX=9606 GN=CLUH PE=1 SV=2 4.53 2244.2 - 274512 - - - 1.4538 - 1.091 0.206 - 116.2 1 2 0 0.0016 9 0 0 0 6.67E+07 9.09E+06 - - - 0.814 0.9911 221125_WJC_METTL3_EV_vs_WT_F02.08986.08986.2 0.449 12-Jul K.LEALSVK.E "sp|Q9C010|IPKB_HUMAN,sp|P43487|RANG_HUMAN,tr|C9JXG8|C9JXG8_HUMAN,tr|F6WQW2|F6WQW2_HUMAN,tr|Q5T0Z6|Q5T0Z6_HUMAN" 5 758.4538 0.29 11191 8986 2 758.453358 380.2342 cAMP-dependent protein kinase inhibitor beta OS=Homo sapiens OX=9606 GN=PKIB PE=1 SV=1 6 2244.6 - 1.50E+06 - - - -0.5894 - 1.396 0.086 - 108.7 1 2 0 -0.0004 7 0 0 0 4.78E+07 1.67E+08 - - - 0.7331 0.9995 221125_WJC_METTL3_EV_vs_WT_F02.08987.08987.2 3.27E-06 22-Oct K.GSFSDTGLGDGK.M "sp|Q9Y2W1|TR150_HUMAN,tr|A0A3B3ITZ9|A0A3B3ITZ9_HUMAN" 2 1139.5095 3.44 11192 8987 2 1139.506792 570.762 Thyroid hormone receptor-associated protein 3 OS=Homo sapiens OX=9606 GN=THRAP3 PE=1 SV=2 4.21 2244.7 - 493324 - - - -2.3607 - 1.721 0.53 - 218.5 1 2 0 -0.0027 12 0 0 0 5.76E+07 1.67E+07 - - - 4.3832 0.9991 221125_WJC_METTL3_EV_vs_WT_F02.08995.08995.2 0.0043 14-Aug K.YVDPVISK.R "sp|Q14244|MAP7_HUMAN,tr|A0A087WZ40|A0A087WZ40_HUMAN" 2 919.5015 1.08 11193 8995 2 919.501205 460.758 Ensconsin OS=Homo sapiens OX=9606 GN=MAP7 PE=1 SV=1 5.83 2246 - 1.38E+06 - - - -0.3034 - 1.361 0.339 - 177.3 1 2 0 -0.0003 8 0 0 0 9.56E+07 8.85E+07 - - - 2.4743 0.9955 221125_WJC_METTL3_EV_vs_WT_F02.08997.08997.2 0.000229 22-Nov K.GSFSDTGLGDGK[136.11].M "sp|Q9Y2W1|TR150_HUMAN,tr|A0A3B3ITZ9|A0A3B3ITZ9_HUMAN" 2 1147.5237 3.44 11194 8997 2 1147.517351 574.7691 Thyroid hormone receptor-associated protein 3 OS=Homo sapiens OX=9606 GN=THRAP3 PE=1 SV=2 4.21 2246.2 - 355260 - - - -5.5171 - 1.795 0.514 - 169.8 1 2 0 -0.0063 12 0 0 0 5.76E+07 1.67E+07 - - - 4.3747 0.9993 221125_WJC_METTL3_EV_vs_WT_F02.09006.09006.2 0.0222 16-Sep R.LENEIQTYR.S "sp|P13645|K1C10_HUMAN,tr|A0A1B0GVI3|A0A1B0GVI3_HUMAN" 2 1164.5775 2.39 11198 9006 2 1164.578472 583.296 "Keratin, type I cytoskeletal 10 OS=Homo sapiens OX=9606 GN=KRT10 PE=1 SV=6" 4.53 2247.4 - 132763 - - - 0.8329 - 1.527 0.358 - 201.9 1 2 0 0.001 9 0 0 0 5.22E+06 2.18E+06 - - - 2.9095 0.999 221125_WJC_METTL3_EV_vs_WT_F02.09011.09011.2 0.0334 18-Aug R.LLSTDPVTAK[136.11].E "sp|P63010|AP2B1_HUMAN,tr|A0A087WZQ6|A0A087WZQ6_HUMAN,tr|A0A087X253|A0A087X253_HUMAN,tr|A0A087WU93|A0A087WU93_HUMAN,tr|A0A087WYD1|A0A087WYD1_HUMAN" 5 1051.6005 1.11 11200 9011 2 1051.599717 526.8075 AP-2 complex subunit beta OS=Homo sapiens OX=9606 GN=AP2B1 PE=1 SV=1 5.84 2248 - 286740 - - - -0.7218 - 1.446 0.315 - 149.9 1 2 0 -0.0008 10 0 0 0 4.10E+07 3.69E+07 - - - 2.3968 0.9927 221125_WJC_METTL3_EV_vs_WT_F02.09024.09024.2 2.17 12-Aug R.IPVALQR[166.11].Q sp|Q9NUL7|DDX28_HUMAN 1 805.5049 0.97 11206 9024 2 805.504754 403.7597 Probable ATP-dependent RNA helicase DDX28 OS=Homo sapiens OX=9606 GN=DDX28 PE=1 SV=2 9.75 2249.6 - 2.31E+06 - - - -0.2346 - 1.472 0.095 - 201.6 2 2 0 -0.0002 7 0 0 0 1.41E+08 1.45E+08 - - - 0.8332 0.9875 221125_WJC_METTL3_EV_vs_WT_F02.09025.09025.2 1.66 12-Jul R.IFASNLK[136.11].E "sp|Q13895|BYST_HUMAN,tr|H7BY94|H7BY94_HUMAN" 2 799.4683 0.98 11207 9025 2 799.467771 400.7414 Bystin OS=Homo sapiens OX=9606 GN=BYSL PE=1 SV=3 8.75 2249.6 - 1.90E+06 - - - -0.7105 - 1.209 0.119 - 91.4 1 2 0 -0.0006 7 0 0 0 1.27E+08 1.30E+08 - - - 0.5211 0.9979 221125_WJC_METTL3_EV_vs_WT_F02.09026.09026.2 0.00349 18-Nov R.LLSTDPVTAK.E "sp|P63010|AP2B1_HUMAN,tr|A0A087WZQ6|A0A087WZQ6_HUMAN,tr|A0A087X253|A0A087X253_HUMAN,tr|A0A087WU93|A0A087WU93_HUMAN,tr|A0A087WYD1|A0A087WYD1_HUMAN" 5 1043.5863 1.11 11208 9026 2 1043.585834 522.8004 AP-2 complex subunit beta OS=Homo sapiens OX=9606 GN=AP2B1 PE=1 SV=1 5.84 2249.7 - 582269 - - - -0.4235 - 1.622 0.185 - 303.5 1 2 0 -0.0004 10 0 0 0 4.10E+07 3.69E+07 - - - 1.7573 0.9982 221125_WJC_METTL3_EV_vs_WT_F02.09028.09028.2 26.2 14-Aug R.LLEQQELR[166.11].E sp|Q9BSC4|NOL10_HUMAN 1 1037.5745 1.28 11210 9028 2 1037.574697 519.7945 Nucleolar protein 10 OS=Homo sapiens OX=9606 GN=NOL10 PE=1 SV=1 4.53 2250 - 546764 - - - 0.2101 - 1.657 0.18 - 250.7 1 2 0 0.0002 8 0 0 0 6.01E+07 4.69E+07 - - - 1.8935 0.8519 221125_WJC_METTL3_EV_vs_WT_F02.09029.09029.2 16.8 18-Apr K.RGDSFLDGTR.C "sp|Q76LX8|ATS13_HUMAN,tr|E7EV88|E7EV88_HUMAN" 2 1122.5418 74.06 11211 9029 2 1122.54239 562.2782 A disintegrin and metalloproteinase with thrombospondin motifs 13 OS=Homo sapiens OX=9606 GN=ADAMTS13 PE=1 SV=1 5.96 2250.1 - 304881 - - - 0.539 - 1.027 0.027 - 61.4 9 2 0 0.0006 10 0 0 0 2.92E+07 3.94E+05 - - - -1.1117 0.9961 221125_WJC_METTL3_EV_vs_WT_F02.09032.09032.2 0.411 14-Aug R.LLEQQELR.E sp|Q9BSC4|NOL10_HUMAN 1 1027.5662 1.28 11212 9032 2 1027.566593 514.7904 Nucleolar protein 10 OS=Homo sapiens OX=9606 GN=NOL10 PE=1 SV=1 4.53 2250.6 - 1.04E+06 - - - 0.3737 - 1.572 0.124 - 245.9 1 2 0 0.0004 8 0 0 0 6.01E+07 4.69E+07 - - - 1.321 0.9981 221125_WJC_METTL3_EV_vs_WT_F02.09040.09040.2 0.0121 16-Jul R.VMEPLTASR.L "sp|Q9NQ55|SSF1_HUMAN,tr|A0A0B4J1V8|A0A0B4J1V8_HUMAN,tr|A0A0A6YYI3|A0A0A6YYI3_HUMAN" 3 1002.5168 0.71 11218 9040 2 1002.5192 502.2657 Suppressor of SWI4 1 homolog OS=Homo sapiens OX=9606 GN=PPAN PE=2 SV=1 5.97 2251.6 - 233759 - - - 2.378 - 1.471 0.353 - 155.3 1 2 0 0.0024 9 0 0 0 5.01E+06 7.10E+06 - - - 2.7641 0.998 221125_WJC_METTL3_EV_vs_WT_F02.09044.09044.2 0.066 12-Aug K.IPENIYR[166.11].G "sp|P42704|LPPRC_HUMAN,tr|A0A804HI14|A0A804HI14_HUMAN,tr|A0A804HL40|A0A804HL40_HUMAN,tr|A0A804HKJ0|A0A804HKJ0_HUMAN,tr|A0A804HKR3|A0A804HKR3_HUMAN,tr|A0A804HIN4|A0A804HIN4_HUMAN,tr|A0A804HLG8|A0A804HLG8_HUMAN,tr|A0A804HIV5|A0A804HIV5_HUMAN,tr|A0A804HHY9|A0A804HHY9_HUMAN,tr|A0A804HJH8|A0A804HJH8_HUMAN,tr|B8ZZ38|B8ZZ38_HUMAN,tr|A0A804HI40|A0A804HI40_HUMAN,tr|A0A804HJZ1|A0A804HJZ1_HUMAN,tr|C9JCA9|C9JCA9_HUMAN,tr|A0A804HIQ7|A0A804HIQ7_HUMAN,tr|A0A804HK30|A0A804HK30_HUMAN,tr|A0A804HKI2|A0A804HKI2_HUMAN,tr|A0A804HJI0|A0A804HJI0_HUMAN,tr|A0A804HIG4|A0A804HIG4_HUMAN,tr|A0A804HK02|A0A804HK02_HUMAN" 20 913.4897 0.67 11220 9044 2 913.490226 457.7521 "Leucine-rich PPR motif-containing protein, mitochondrial OS=Homo sapiens OX=9606 GN=LRPPRC PE=1 SV=3" 6 2252 - 2.34E+06 - - - 0.59 - 1.454 0.224 - 223 1 2 0 0.0005 7 0 0 0 8.08E+07 1.21E+08 - - - 1.8813 0.8686 221125_WJC_METTL3_EV_vs_WT_F02.09045.09045.2 0.00833 14-Sep Y.VGAFADAR[166.11].S sp|Q9ULL4|PLXB3_HUMAN 1 815.4165 0.98 11221 9045 2 815.417816 408.7155 Plexin-B3 OS=Homo sapiens OX=9606 GN=PLXNB3 PE=1 SV=2 5.81 2252.1 - 2.52E+06 - - - 1.5869 - 1.653 0.207 - 176.6 1 1 0 0.0013 8 0 0 0 4.03E+09 4.12E+09 - - - 2.0853 0.9973 221125_WJC_METTL3_EV_vs_WT_F02.09052.09052.2 0.473 12-May R.IPMEMTR.V "sp|Q16540|RM23_HUMAN,tr|H7C2P7|H7C2P7_HUMAN,tr|A8MYK1|A8MYK1_HUMAN,tr|A8MVT4|A8MVT4_HUMAN,tr|A6NJD9|A6NJD9_HUMAN" 5 876.4197 1.2 11226 9052 2 876.419359 439.2171 "39S ribosomal protein L23, mitochondrial OS=Homo sapiens OX=9606 GN=MRPL23 PE=1 SV=1" 6 2252.8 - 264187 - - - -0.4404 - 1.218 0.256 - 77.4 1 2 0 -0.0004 7 0 0 0 4.12E+07 3.45E+07 - - - 1.5566 0.9976 221125_WJC_METTL3_EV_vs_WT_F02.09056.09056.2 0.023 14-Aug K.LVIEEAER[166.11].S sp|P50991|TCPD_HUMAN 1 967.5214 0.37 11229 9056 2 967.520838 484.768 T-complex protein 1 subunit delta OS=Homo sapiens OX=9606 GN=CCT4 PE=1 SV=4 4.25 2253.2 - 1.61E+06 - - - -0.5612 - 1.673 0.148 - 243.5 1 2 0 -0.0005 8 0 0 0 1.55E+09 4.19E+09 - - - 1.686 0.9969 221125_WJC_METTL3_EV_vs_WT_F02.09062.09062.2 0.328 14-Jul K.LVIEEAER.S sp|P50991|TCPD_HUMAN 1 957.5131 0.37 11233 9062 2 957.513417 479.7638 T-complex protein 1 subunit delta OS=Homo sapiens OX=9606 GN=CCT4 PE=1 SV=4 4.25 2253.8 - 884513 - - - 0.3196 - 1.497 0.167 - 188 1 2 0 0.0003 8 0 0 0 1.55E+09 4.19E+09 - - - 1.4912 0.9996 221125_WJC_METTL3_EV_vs_WT_F02.09063.09063.2 0.00545 16-Jul R.LEDAADVYR[166.11].G "sp|Q9BXJ9|NAA15_HUMAN,tr|A0A0B4J1W3|A0A0B4J1W3_HUMAN" 2 1060.5065 0.21 11234 9063 2 1060.507154 531.2605 "N-alpha-acetyltransferase 15, NatA auxiliary subunit OS=Homo sapiens OX=9606 GN=NAA15 PE=1 SV=1" 4.03 2253.9 - 429999 - - - 0.6553 - 1.858 0.355 - 143.6 1 2 0 0.0007 9 0 0 0 9.07E+06 4.40E+07 - - - 3.4551 0.9995 221125_WJC_METTL3_EV_vs_WT_F02.09065.09065.2 0.0264 18-Sep R.VLTTAGSYVR[166.11].D sp|O43747|AP1G1_HUMAN 1 1075.5901 0.52 11236 9065 2 1075.589739 538.8023 AP-1 complex subunit gamma-1 OS=Homo sapiens OX=9606 GN=AP1G1 PE=1 SV=5 8.72 2254.1 - 319760 - - - -0.3626 - 1.796 0.322 - 285.4 1 2 0 -0.0004 10 0 0 0 3.72E+06 7.17E+06 - - - 3.0537 0.9815 221125_WJC_METTL3_EV_vs_WT_F02.09069.09069.2 0.632 12-Jul K.IIDAALR.A "sp|P20674|COX5A_HUMAN,tr|H3BNX8|H3BNX8_HUMAN,tr|H3BV69|H3BV69_HUMAN,tr|H3BRM5|H3BRM5_HUMAN" 4 770.465 2.78 11238 9069 2 770.463854 386.2398 "Cytochrome c oxidase subunit 5A, mitochondrial OS=Homo sapiens OX=9606 GN=COX5A PE=1 SV=2" 5.84 2254.6 - 1.74E+06 - - - -1.5367 - 1.272 0.096 - 122.3 1 2 0 -0.0012 7 0 0 0 2.16E+08 7.76E+07 - - - 0.512 0.9992 221125_WJC_METTL3_EV_vs_WT_F02.09073.09073.2 0.0013 26-May R.SSFYPDGGDQETAK.T "sp|Q9NYF8|BCLF1_HUMAN,tr|H0YF00|H0YF00_HUMAN,tr|E9PKI6|E9PKI6_HUMAN,tr|A0A1W2PQ43|A0A1W2PQ43_HUMAN,tr|E9PK91|E9PK91_HUMAN,tr|E9PJA7|E9PJA7_HUMAN,tr|E9PK09|E9PK09_HUMAN,tr|E9PQN2|E9PQN2_HUMAN" 8 1500.6369 6.43 11242 9073 2 1500.638114 751.3257 Bcl-2-associated transcription factor 1 OS=Homo sapiens OX=9606 GN=BCLAF1 PE=1 SV=2 4.03 2255.1 - 104857 - - - 0.8303 - 1.004 0.507 - 40.4 1 2 0 0.0012 14 0 0 0 5.04E+06 7.84E+05 - - - 2.7953 0.9878 221125_WJC_METTL3_EV_vs_WT_F02.09082.09082.2 1.35 12-Jun K.IIDAALR[166.11].A "sp|P20674|COX5A_HUMAN,tr|H3BNX8|H3BNX8_HUMAN,tr|H3BV69|H3BV69_HUMAN,tr|H3BRM5|H3BRM5_HUMAN" 4 780.4733 2.53 11247 9082 2 780.472223 391.2439 "Cytochrome c oxidase subunit 5A, mitochondrial OS=Homo sapiens OX=9606 GN=COX5A PE=1 SV=2" 5.84 2256.2 - 1.96E+06 - - - -1.3902 - 1.146 0.171 - 89.7 1 2 0 -0.0011 7 0 0 0 2.05E+08 8.10E+07 - - - 0.7355 0.994 221125_WJC_METTL3_EV_vs_WT_F02.09097.09097.2 0.0061 16-Sep R.LEDAADVYR.G "sp|Q9BXJ9|NAA15_HUMAN,tr|A0A0B4J1W3|A0A0B4J1W3_HUMAN" 2 1050.4982 0.21 11255 9097 2 1050.492911 526.2564 "N-alpha-acetyltransferase 15, NatA auxiliary subunit OS=Homo sapiens OX=9606 GN=NAA15 PE=1 SV=1" 4.03 2258 - 240343 - - - -5.0243 - 1.763 0.387 - 234.2 1 2 0 -0.0053 9 0 0 0 9.07E+06 4.40E+07 - - - 3.5381 0.986 221125_WJC_METTL3_EV_vs_WT_F02.09111.09111.2 0.106 14-Sep R.IGVLDEGK[136.11].M "sp|P46781|RS9_HUMAN,tr|C9JM19|C9JM19_HUMAN,tr|B5MCT8|B5MCT8_HUMAN" 3 837.4687 0.98 11258 9111 2 837.465362 419.7416 40S ribosomal protein S9 OS=Homo sapiens OX=9606 GN=RPS9 PE=1 SV=3 4.37 2260 - 1.20E+07 - - - -4.0252 - 1.57 0.22 - 177.8 1 2 0 -0.0034 8 0 0 0 1.28E+09 1.30E+09 - - - 2.0253 0.9916 221125_WJC_METTL3_EV_vs_WT_F02.09113.09113.2 0.0793 14-Aug R.IGVLDEGK.M "sp|P46781|RS9_HUMAN,tr|C9JM19|C9JM19_HUMAN,tr|B5MCT8|B5MCT8_HUMAN" 3 829.4545 0.99 11260 9113 2 829.451359 415.7345 40S ribosomal protein S9 OS=Homo sapiens OX=9606 GN=RPS9 PE=1 SV=3 4.37 2260.1 - 1.02E+07 - - - -3.8266 - 1.796 0.208 - 180.7 1 2 0 -0.0032 8 0 0 0 1.29E+09 1.30E+09 - - - 2.3423 0.8396 221125_WJC_METTL3_EV_vs_WT_F02.09129.09129.2 4.44 12-May K.ALTSFER.D "sp|P40939|ECHA_HUMAN,tr|A0A2R8YG21|A0A2R8YG21_HUMAN,tr|H0YFD6|H0YFD6_HUMAN,tr|A0A2R8Y4F5|A0A2R8Y4F5_HUMAN" 4 822.4236 0.85 11269 9129 2 822.420432 412.2191 "Trifunctional enzyme subunit alpha, mitochondrial OS=Homo sapiens OX=9606 GN=HADHA PE=1 SV=2" 6.05 2261.9 - 3.99E+06 - - - -3.8131 - 1.169 0.101 - 86.2 3 2 0 -0.0031 7 0 0 0 1.29E+08 1.50E+08 - - - 0.0676 0.9834 221125_WJC_METTL3_EV_vs_WT_F02.09136.09136.2 0.721 14-May R.GYIGVVNR.S "sp|Q05193|DYN1_HUMAN,sp|P50570|DYN2_HUMAN,tr|A0A0D9SFB1|A0A0D9SFB1_HUMAN,tr|A0A1B0GUX5|A0A1B0GUX5_HUMAN,tr|A0A1B0GU67|A0A1B0GU67_HUMAN,tr|A0A0D9SFE4|A0A0D9SFE4_HUMAN,tr|A0A0U1RQP1|A0A0U1RQP1_HUMAN" 7 876.4818 0.75 11272 9136 2 876.481525 439.2482 Dynamin-1 OS=Homo sapiens OX=9606 GN=DNM1 PE=1 SV=2 8.75 2262.7 - 750137 - - - -0.2578 - 1.026 0.204 - 54.6 6 2 0 -0.0002 8 0 0 0 2.05E+07 2.75E+07 - - - 0.2775 0.7618 221125_WJC_METTL3_EV_vs_WT_F02.09144.09144.2 3.97 16-Jun R.LVPSVNGVR[166.11].R "sp|P11586|C1TC_HUMAN,tr|F5H2F4|F5H2F4_HUMAN,tr|V9GZ78|V9GZ78_HUMAN,tr|V9GYY3|V9GYY3_HUMAN,tr|A0A494C1T2|A0A494C1T2_HUMAN" 5 949.5584 1.67 11275 9144 2 949.554942 475.7865 "C-1-tetrahydrofolate synthase, cytoplasmic OS=Homo sapiens OX=9606 GN=MTHFD1 PE=1 SV=4" 9.75 2263.8 - 1.27E+06 - - - -3.6786 - 1.104 0.079 - 101.9 3 2 0 -0.0035 9 0 0 0 5.46E+08 3.27E+08 - - - -0.3035 0.9381 221125_WJC_METTL3_EV_vs_WT_F02.09167.09167.2 6.68 14-Jul K.MLGEALSK[136.11].N "sp|Q99623|PHB2_HUMAN,tr|F5GY37|F5GY37_HUMAN" 2 855.4615 0.76 11280 9167 2 855.458621 428.738 Prohibitin-2 OS=Homo sapiens OX=9606 GN=PHB2 PE=1 SV=2 5.75 2267.1 - 3.24E+06 - - - -3.4122 - 1.51 0.075 - 160.2 4 2 0 -0.0029 8 0 0 0 3.77E+08 4.94E+08 - - - 0.568 0.9967 221125_WJC_METTL3_EV_vs_WT_F02.09180.09180.2 0.799 12-Jul R.LDAELVK.Y "sp|Q9NZZ3|CHMP5_HUMAN,tr|H3BLZ2|H3BLZ2_HUMAN" 2 786.4487 1.35 11285 9180 2 786.447267 394.2316 Charged multivesicular body protein 5 OS=Homo sapiens OX=9606 GN=CHMP5 PE=1 SV=1 4.37 2268.9 - 2.39E+06 - - - -1.8475 - 1.575 0.194 - 98.2 1 2 0 -0.0015 7 0 0 0 3.28E+08 2.43E+08 - - - 1.9128 0.9858 221125_WJC_METTL3_EV_vs_WT_F02.09199.09199.2 1.14 12-Aug R.QLYMVSK[136.11].E sp|Q08J23|NSUN2_HUMAN 1 875.4666 0.85 11295 9199 2 875.467459 438.7406 RNA cytosine C(5)-methyltransferase NSUN2 OS=Homo sapiens OX=9606 GN=NSUN2 PE=1 SV=2 8.59 2271.3 - 710628 - - - 0.9526 - 1.239 0.113 - 289.6 1 2 0 0.0008 7 0 0 0 6.53E+07 7.69E+07 - - - 0.5544 0.9988 221125_WJC_METTL3_EV_vs_WT_F02.09201.09201.2 6.07E-07 16-Oct R.YDDMAAAMK[136.11].A "sp|P31946|1433B_HUMAN,sp|P61981|1433G_HUMAN,tr|Q4VY19|Q4VY19_HUMAN,tr|Q4VY20|Q4VY20_HUMAN,tr|A0A0J9YWE8|A0A0J9YWE8_HUMAN" 5 1022.4293 1.06 11297 9201 2 1022.431203 512.2219 14-3-3 protein beta\alpha OS=Homo sapiens OX=9606 GN=YWHAB PE=1 SV=3 4.21 2271.5 - 164243 - - - 1.9072 - 1.778 0.306 - 241.3 1 2 0 0.0019 9 0 0 0 4.66E+07 4.40E+07 - - - 2.9654 0.9923 221125_WJC_METTL3_EV_vs_WT_F02.09209.09209.2 8.11 12-Jul R.LDAELVK[136.11].Y "sp|Q9NZZ3|CHMP5_HUMAN,tr|H3BLZ2|H3BLZ2_HUMAN" 2 794.4629 1.35 11301 9209 2 794.463128 398.2387 Charged multivesicular body protein 5 OS=Homo sapiens OX=9606 GN=CHMP5 PE=1 SV=1 4.37 2272.5 - 5.77E+06 - - - 0.2618 - 1.351 0.112 - 115.6 1 2 0 0.0002 7 0 0 0 3.28E+08 2.43E+08 - - - 0.8214 0.9708 221125_WJC_METTL3_EV_vs_WT_F02.09210.09210.2 0.489 12-May R.VLVDVER.G sp|P08621|RU17_HUMAN 1 828.4705 0.77 11302 9210 2 828.469359 415.2425 U1 small nuclear ribonucleoprotein 70 kDa OS=Homo sapiens OX=9606 GN=SNRNP70 PE=1 SV=2 4.37 2272.5 - 4.59E+06 - - - -1.399 - 1.011 0.146 - 97 1 2 0 -0.0012 7 0 0 0 2.30E+08 2.98E+08 - - - 0.1537 1 221125_WJC_METTL3_EV_vs_WT_F02.09214.09214.2 2.94E-07 16-Oct R.YDDMAAAMK.A "sp|P31946|1433B_HUMAN,sp|P61981|1433G_HUMAN,tr|Q4VY19|Q4VY19_HUMAN,tr|Q4VY20|Q4VY20_HUMAN,tr|A0A0J9YWE8|A0A0J9YWE8_HUMAN" 5 1014.4151 1.06 11304 9214 2 1014.413719 508.2148 14-3-3 protein beta\alpha OS=Homo sapiens OX=9606 GN=YWHAB PE=1 SV=3 4.21 2273 - 513003 - - - -1.315 - 1.849 0.701 - 252 1 2 0 -0.0013 9 0 0 0 4.66E+07 4.40E+07 - - - 5.9964 0.9758 221125_WJC_METTL3_EV_vs_WT_F02.09217.09217.2 1.57 12-Apr K.ELSEYVR[166.11].N "sp|Q7L1Q6|BZW1_HUMAN,tr|C9IZ80|C9IZ80_HUMAN" 2 904.453 2.48 11306 9217 2 904.452995 453.2338 Basic leucine zipper and W2 domain-containing protein 1 OS=Homo sapiens OX=9606 GN=BZW1 PE=1 SV=1 4.53 2273.3 - 628448 - - - 0.031 - 1.086 0.099 - 78.8 1 2 0 0 7 0 0 0 4.56E+07 1.84E+07 - - - 0.0336 0.993 221125_WJC_METTL3_EV_vs_WT_F02.09220.09220.2 0.869 12-Jul K.VALSTLR[166.11].D "sp|O75818|RPP40_HUMAN,tr|A0A087X1N3|A0A087X1N3_HUMAN,tr|X6RLL4|X6RLL4_HUMAN" 3 768.4733 0.52 11307 9220 2 768.472641 385.2439 Ribonuclease P protein subunit p40 OS=Homo sapiens OX=9606 GN=RPP40 PE=1 SV=3 9.72 2273.7 - 1.18E+06 - - - -0.868 - 1.544 0.091 - 159.5 2 2 0 -0.0007 7 0 0 0 2.24E+07 4.31E+07 - - - 0.9548 0.9968 221125_WJC_METTL3_EV_vs_WT_F02.09225.09225.2 0.289 12-Jul K.YTDLVPK.E "sp|Q13573|SNW1_HUMAN,tr|G3V3A4|G3V3A4_HUMAN,tr|G3V5R3|G3V5R3_HUMAN" 3 834.4487 0.67 11310 9225 2 834.45014 418.2316 SNW domain-containing protein 1 OS=Homo sapiens OX=9606 GN=SNW1 PE=1 SV=1 5.83 2274.2 - 1.83E+06 - - - 1.7017 - 1.129 0.341 - 144.5 1 2 0 0.0014 7 0 0 0 4.99E+08 7.47E+08 - - - 1.9436 0.9991 221125_WJC_METTL3_EV_vs_WT_F02.09240.09240.2 0.0701 14-Aug R.LESTYEIR.Q "sp|O60306|AQR_HUMAN,tr|H0YH15|H0YH15_HUMAN" 2 1009.508 1.52 11317 9240 2 1009.508737 505.7613 RNA helicase aquarius OS=Homo sapiens OX=9606 GN=AQR PE=1 SV=4 4.53 2276.1 - 516051 - - - 0.7043 - 1.617 0.281 - 212.8 1 2 0 0.0007 8 0 0 0 1.84E+07 1.21E+07 - - - 2.5656 0.967 221125_WJC_METTL3_EV_vs_WT_F02.09248.09248.2 0.487 14-May K.LLPVDC[160.03]ER.K sp|Q8NC56|LEMD2_HUMAN 1 1000.5012 0.76 11322 9248 2 1000.503206 501.2579 LEM domain-containing protein 2 OS=Homo sapiens OX=9606 GN=LEMD2 PE=1 SV=1 4.37 2277.1 - 300113 - - - 2.039 - 1.137 0.148 - 74.4 2 2 0 0.002 8 0 0 0 1.42E+07 1.88E+07 - - - 0.3862 0.9996 221125_WJC_METTL3_EV_vs_WT_F02.09251.09251.2 0.462 12-Aug K.TMYLEDR[166.11].T "sp|P20340|RAB6A_HUMAN,sp|Q9NRW1|RAB6B_HUMAN,tr|F5GX61|F5GX61_HUMAN,tr|C9JB90|C9JB90_HUMAN,tr|J3KR73|J3KR73_HUMAN" 5 936.425 1.59 11323 9251 2 936.424311 469.2198 Ras-related protein Rab-6A OS=Homo sapiens OX=9606 GN=RAB6A PE=1 SV=3 4.37 2277.5 - 2.36E+06 - - - -0.7764 - 1.66 0.358 - 301.8 1 2 0 -0.0007 7 0 0 0 1.66E+08 1.04E+08 - - - 3.2908 0.9959 221125_WJC_METTL3_EV_vs_WT_F02.09253.09253.2 0.817 12-Jul K.APLVLK[136.11]D.- "sp|Q99497|PARK7_HUMAN,tr|K7EN27|K7EN27_HUMAN,tr|K7ELW0|K7ELW0_HUMAN" 3 762.4731 0.001 11324 9253 2 762.473146 382.2438 Parkinson disease protein 7 OS=Homo sapiens OX=9606 GN=PARK7 PE=1 SV=2 6.13 2277.8 - 1.98E+06 - - - 0.0734 - 1.375 0.163 - 173.4 1 2 0 0.0001 7 0 0 0 0.00E+00 1.15E+09 - - - 1.2539 0.9997 221125_WJC_METTL3_EV_vs_WT_F02.09266.09266.2 0.0124 16-Sep K.EVVIVSATR[166.11].T "sp|P24752|THIL_HUMAN,tr|A0A5F9ZHL7|A0A5F9ZHL7_HUMAN,tr|A0A5F9ZHJ7|A0A5F9ZHJ7_HUMAN,tr|A0A5F9ZHH9|A0A5F9ZHH9_HUMAN,tr|A0A5F9ZHL1|A0A5F9ZHL1_HUMAN,tr|E9PRQ6|E9PRQ6_HUMAN" 6 982.5687 1.22 11328 9266 2 982.568642 492.2916 "Acetyl-CoA acetyltransferase, mitochondrial OS=Homo sapiens OX=9606 GN=ACAT1 PE=1 SV=1" 6.1 2279.5 - 3.12E+06 - - - -0.0234 - 1.828 0.367 - 457.1 1 2 0 0 9 0 0 0 4.40E+08 3.62E+08 - - - 3.4968 0.9995 221125_WJC_METTL3_EV_vs_WT_F02.09270.09270.2 0.0672 16-Sep K.EVVIVSATR.T "sp|P24752|THIL_HUMAN,tr|A0A5F9ZHL7|A0A5F9ZHL7_HUMAN,tr|A0A5F9ZHJ7|A0A5F9ZHJ7_HUMAN,tr|A0A5F9ZHH9|A0A5F9ZHH9_HUMAN,tr|A0A5F9ZHL1|A0A5F9ZHL1_HUMAN,tr|E9PRQ6|E9PRQ6_HUMAN" 6 972.5604 1.22 11330 9270 2 972.559951 487.2875 "Acetyl-CoA acetyltransferase, mitochondrial OS=Homo sapiens OX=9606 GN=ACAT1 PE=1 SV=1" 6.1 2280 - 3.60E+06 - - - -0.4565 - 1.847 0.301 - 463.5 1 2 0 -0.0004 9 0 0 0 4.41E+08 3.62E+08 - - - 3.0391 0.9932 221125_WJC_METTL3_EV_vs_WT_F02.09275.09275.2 0.186 16-Jul K.VIAAMTVGK[136.11].D "sp|P63010|AP2B1_HUMAN,tr|K7EJX1|K7EJX1_HUMAN,tr|K7ERB2|K7ERB2_HUMAN,tr|A0A087WZQ6|A0A087WZQ6_HUMAN,tr|K7EKZ5|K7EKZ5_HUMAN,tr|A0A087X253|A0A087X253_HUMAN,tr|K7EN71|K7EN71_HUMAN,tr|A0A087WXS3|A0A087WXS3_HUMAN,tr|A0A087WU93|A0A087WU93_HUMAN,tr|A0A087WYD1|A0A087WYD1_HUMAN" 10 896.5245 0.71 11334 9275 2 896.520756 449.2695 AP-2 complex subunit beta OS=Homo sapiens OX=9606 GN=AP2B1 PE=1 SV=1 8.72 2280.5 - 1.06E+06 - - - -4.1471 - 1.499 0.344 - 147.8 1 2 0 -0.0037 9 0 0 0 2.46E+07 3.48E+07 - - - 2.7517 0.9991 221125_WJC_METTL3_EV_vs_WT_F02.09279.09279.2 0.0141 12-Jun R.IGNSYFK.E sp|P31948|STIP1_HUMAN 1 827.4178 1.47 11336 9279 2 827.417839 414.7162 Stress-induced-phosphoprotein 1 OS=Homo sapiens OX=9606 GN=STIP1 PE=1 SV=1 8.59 2281.1 - 1.95E+06 - - - 0.1027 - 1.433 0.314 - 73.4 1 2 0 0.0001 7 0 0 0 7.93E+07 5.38E+07 - - - 2.5001 0.9967 221125_WJC_METTL3_EV_vs_WT_F02.09280.09280.2 0.225 12-Jul K.VGFEVEK[136.11].K "sp|Q9UBB4|ATX10_HUMAN,tr|B1AHE3|B1AHE3_HUMAN" 2 814.4316 0.69 11337 9280 2 814.431202 408.2231 Ataxin-10 OS=Homo sapiens OX=9606 GN=ATXN10 PE=1 SV=1 4.53 2281.1 - 1.02E+06 - - - -0.5132 - 1.203 0.244 - 97.1 1 2 0 -0.0004 7 0 0 0 2.69E+07 3.90E+07 - - - 1.4287 0.9993 221125_WJC_METTL3_EV_vs_WT_F02.09281.09281.2 0.00843 16-Aug K.VIAAMTVGK.D "sp|P63010|AP2B1_HUMAN,tr|K7EJX1|K7EJX1_HUMAN,tr|K7ERB2|K7ERB2_HUMAN,tr|A0A087WZQ6|A0A087WZQ6_HUMAN,tr|K7EKZ5|K7EKZ5_HUMAN,tr|A0A087X253|A0A087X253_HUMAN,tr|K7EN71|K7EN71_HUMAN,tr|A0A087WXS3|A0A087WXS3_HUMAN,tr|A0A087WU93|A0A087WU93_HUMAN,tr|A0A087WYD1|A0A087WYD1_HUMAN" 10 888.5103 0.6 11338 9281 2 888.510235 445.2624 AP-2 complex subunit beta OS=Homo sapiens OX=9606 GN=AP2B1 PE=1 SV=1 8.72 2281.2 - 765805 - - - -0.0439 - 1.471 0.336 - 155.6 1 2 0 0 9 0 0 0 2.48E+07 4.10E+07 - - - 2.6392 0.9529 221125_WJC_METTL3_EV_vs_WT_F02.09286.09286.2 0.0343 14-Sep F.LLAQTTLR.N "sp|Q8TAV4|STML3_HUMAN,sp|P27105|STOM_HUMAN,tr|F8VSL7|F8VSL7_HUMAN" 3 914.5549 1.21 11341 9286 2 914.554059 458.2847 Stomatin-like protein 3 OS=Homo sapiens OX=9606 GN=STOML3 PE=1 SV=1 9.75 2281.9 - 1.08E+06 - - - -0.9371 - 1.743 0.267 - 250 1 1 0 -0.0009 8 0 0 0 9.33E+07 7.69E+07 - - - 2.6885 0.9976 221125_WJC_METTL3_EV_vs_WT_F02.09292.09292.2 0.106 12-Jul R.LAADDFR.T "sp|Q04695|K1C17_HUMAN,sp|P13645|K1C10_HUMAN,sp|O76015|KRT38_HUMAN,sp|Q2M2I5|K1C24_HUMAN,sp|Q15323|K1H1_HUMAN,sp|P02533|K1C14_HUMAN,sp|P05783|K1C18_HUMAN,sp|P08727|K1C19_HUMAN,sp|P08779|K1C16_HUMAN,sp|Q7Z3Y7|K1C28_HUMAN,sp|Q14532|K1H2_HUMAN,sp|P19012|K1C15_HUMAN,sp|O76013|KRT36_HUMAN,sp|Q14525|KT33B_HUMAN,sp|Q92764|KRT35_HUMAN,sp|O76014|KRT37_HUMAN,sp|P13646|K1C13_HUMAN,tr|F8VZY9|F8VZY9_HUMAN,tr|K7EPJ9|K7EPJ9_HUMAN,tr|C9JM50|C9JM50_HUMAN,tr|A0A1B0GVI3|A0A1B0GVI3_HUMAN,tr|K7EMD9|K7EMD9_HUMAN,tr|F5GWP8|F5GWP8_HUMAN,tr|K7ERE3|K7ERE3_HUMAN,tr|C4AM86|C4AM86_HUMAN" 25 806.3923 165.59 11345 9292 2 806.391901 404.2034 "Keratin, type I cytoskeletal 17 OS=Homo sapiens OX=9606 GN=KRT17 PE=1 SV=2" 4.21 2282.5 - 4.31E+06 - - - -0.4539 - 1.417 0.207 - 170.2 1 2 0 -0.0004 7 0 0 0 3.06E+08 1.85E+06 - - - 1.6742 0.9966 221125_WJC_METTL3_EV_vs_WT_F02.09296.09296.2 0.058 12-Aug K.FEGAIYR[166.11].K sp|P22102|PUR2_HUMAN 1 864.4369 0.6 11347 9296 2 864.436099 433.2257 Trifunctional purine biosynthetic protein adenosine-3 OS=Homo sapiens OX=9606 GN=GART PE=1 SV=1 6 2282.9 - 2.39E+06 - - - -0.9532 - 1.327 0.212 - 179.5 1 2 0 -0.0008 7 0 0 0 3.64E+07 6.10E+07 - - - 1.503 0.9917 221125_WJC_METTL3_EV_vs_WT_F02.09297.09297.2 0.0019 14-Jul R.VPVDVAYR.R "sp|P58107|EPIPL_HUMAN,sp|Q15149|PLEC_HUMAN,tr|A0A075B730|A0A075B730_HUMAN,tr|H0YDN1|H0YDN1_HUMAN" 4 917.4971 1.73 11348 9297 2 917.500362 459.7558 Epiplakin OS=Homo sapiens OX=9606 GN=EPPK1 PE=1 SV=3 5.81 2283 - 2.04E+06 - - - 3.5913 - 1.438 0.283 - 168.8 1 2 0 0.0033 8 0 0 0 1.13E+09 6.54E+08 - - - 2.2258 0.9996 221125_WJC_METTL3_EV_vs_WT_F02.09309.09309.2 1.05E-05 16-Oct R.YLEDGGLER[166.11].K sp|P07099|HYEP_HUMAN 1 1060.5065 1.06 11357 9309 2 1060.505986 531.2605 Epoxide hydrolase 1 OS=Homo sapiens OX=9606 GN=EPHX1 PE=1 SV=1 4.14 2284.3 - 640071 - - - -0.446 - 1.871 0.329 - 313.2 1 2 0 -0.0005 9 0 0 0 3.53E+07 3.33E+07 - - - 3.2833 0.9805 221125_WJC_METTL3_EV_vs_WT_F02.09311.09311.2 0.81 12-Jul K.TVTIVVR.G sp|P50991|TCPD_HUMAN 1 786.4963 0.34 11358 9311 2 786.495934 394.2554 T-complex protein 1 subunit delta OS=Homo sapiens OX=9606 GN=CCT4 PE=1 SV=4 9.41 2284.5 - 1.24E+07 - - - -0.5149 - 0.984 0.163 - 171.2 1 2 0 -0.0004 7 0 0 0 7.72E+08 2.25E+09 - - - 0.1937 0.9985 221125_WJC_METTL3_EV_vs_WT_F02.09323.09323.2 0.328 12-Jul K.VC[160.03]ADLIR.G "sp|P60866|RS20_HUMAN,tr|E5RJX2|E5RJX2_HUMAN,tr|A0A7P0S5H5|A0A7P0S5H5_HUMAN" 3 845.4429 1.03 11365 9323 2 845.442479 423.7287 40S ribosomal protein S20 OS=Homo sapiens OX=9606 GN=RPS20 PE=1 SV=1 5.8 2286 - 2.70E+07 - - - -0.5252 - 1.637 0.196 - 210 1 2 0 -0.0004 7 0 0 0 1.68E+09 1.63E+09 - - - 2.0502 0.9548 221125_WJC_METTL3_EV_vs_WT_F02.09328.09328.2 0.0645 14-Oct F.LLAQTTLR[166.11].N "sp|Q8TAV4|STML3_HUMAN,sp|P27105|STOM_HUMAN,tr|F8VSL7|F8VSL7_HUMAN" 3 924.5632 1.25 11367 9328 2 924.562206 463.2889 Stomatin-like protein 3 OS=Homo sapiens OX=9606 GN=STOML3 PE=1 SV=1 9.75 2286.6 - 2.53E+06 - - - -1.06 - 1.796 0.267 - 348 1 1 0 -0.001 8 0 0 0 9.13E+07 7.30E+07 - - - 2.7788 0.9996 221125_WJC_METTL3_EV_vs_WT_F02.09330.09330.2 0.00233 12-Aug R.FANYIDK.V "sp|P08670|VIME_HUMAN,tr|B0YJC4|B0YJC4_HUMAN,tr|A0A1B0GTT5|A0A1B0GTT5_HUMAN" 3 869.4283 1.75 11368 9330 2 869.427313 435.7214 Vimentin OS=Homo sapiens OX=9606 GN=VIM PE=1 SV=4 5.83 2286.8 - 2.52E+06 - - - -1.1571 - 1.551 0.414 - 156.9 1 2 0 -0.001 7 0 0 0 9.81E+09 5.61E+09 - - - 3.4892 0.9991 221125_WJC_METTL3_EV_vs_WT_F02.09337.09337.2 0.162 12-Aug R.QLEAIVR[166.11].L "sp|P33992|MCM5_HUMAN,tr|B1AHB1|B1AHB1_HUMAN" 2 837.4948 0.61 11372 9337 2 837.494607 419.7547 DNA replication licensing factor MCM5 OS=Homo sapiens OX=9606 GN=MCM5 PE=1 SV=5 6 2287.6 - 5.05E+06 - - - -0.197 - 1.566 0.265 - 354.5 1 2 0 -0.0002 7 0 0 0 1.05E+08 1.73E+08 - - - 2.4194 0.9992 221125_WJC_METTL3_EV_vs_WT_F02.09338.09338.2 0.0218 12-Jun R.FANYIDK[136.11].V "sp|P08670|VIME_HUMAN,tr|B0YJC4|B0YJC4_HUMAN,tr|A0A1B0GTT5|A0A1B0GTT5_HUMAN" 3 877.4425 1.73 11373 9338 2 877.441591 439.7285 Vimentin OS=Homo sapiens OX=9606 GN=VIM PE=1 SV=4 5.83 2287.7 - 4.62E+06 - - - -1.0576 - 1.314 0.385 - 93.8 1 2 0 -0.0009 7 0 0 0 9.84E+09 5.70E+09 - - - 2.7496 0.9962 221125_WJC_METTL3_EV_vs_WT_F02.09342.09342.2 1.06 16-Aug R.YLEDGGLER.K sp|P07099|HYEP_HUMAN 1 1050.4982 1.06 11375 9342 2 1050.497517 526.2564 Epoxide hydrolase 1 OS=Homo sapiens OX=9606 GN=EPHX1 PE=1 SV=1 4.14 2288.2 - 973971 - - - -0.6397 - 1.403 0.179 - 190.9 1 2 0 -0.0007 9 0 0 0 3.53E+07 3.33E+07 - - - 1.3425 0.9536 221125_WJC_METTL3_EV_vs_WT_F02.09345.09345.2 5 12-Jul R.SEVDMLK.L "sp|P07355|ANXA2_HUMAN,sp|A6NMY6|AXA2L_HUMAN,tr|H0YL33|H0YL33_HUMAN,tr|H0YMW4|H0YMW4_HUMAN" 4 820.4001 1.88 11377 9345 2 820.396789 411.2073 Annexin A2 OS=Homo sapiens OX=9606 GN=ANXA2 PE=1 SV=2 4.37 2288.5 - 2.01E+06 - - - -3.981 - 1.491 0.103 - 197.3 1 2 0 -0.0033 7 0 0 0 1.21E+08 6.44E+07 - - - 1.0664 0.9989 221125_WJC_METTL3_EV_vs_WT_F02.09346.09346.2 0.00188 14-Jul R.SMMSAYER.S "sp|P18583|SON_HUMAN,sp|P18583|SON_HUMAN,sp|P18583|SON_HUMAN,sp|P18583|SON_HUMAN,tr|H7C1M2|H7C1M2_HUMAN,tr|H7C1M2|H7C1M2_HUMAN" 6 973.3997 1.43 11378 9346 2 973.397438 487.7071 Protein SON OS=Homo sapiens OX=9606 GN=SON PE=1 SV=4 5.72 2288.6 - 752893 - - - -2.3618 - 1.312 0.464 - 230.8 1 2 0 -0.0023 8 0 0 0 1.89E+07 1.32E+07 - - - 3.2864 0.9992 221125_WJC_METTL3_EV_vs_WT_F02.09350.09350.2 0.032 18-Aug K.LLSESAQPLK.K sp|Q9H3N1|TMX1_HUMAN 1 1084.6128 999 11380 9350 2 1084.613439 543.3137 Thioredoxin-related transmembrane protein 1 OS=Homo sapiens OX=9606 GN=TMX1 PE=1 SV=1 6 2289.2 - 490565 - - - 0.5661 - 1.819 0.271 - 174.6 1 2 0 0.0006 10 0 0 0 2.12E+07 0.00E+00 - - - 2.7124 0.9957 221125_WJC_METTL3_EV_vs_WT_F02.09359.09359.2 19 12-Jul K.TVTIVVR[166.11].G sp|P50991|TCPD_HUMAN 1 796.5046 0.34 11383 9359 2 796.503888 399.2596 T-complex protein 1 subunit delta OS=Homo sapiens OX=9606 GN=CCT4 PE=1 SV=4 9.41 2290.4 - 4.10E+07 - - - -0.9052 - 1.662 0.09 - 170.5 1 2 0 -0.0007 7 0 0 0 7.54E+08 2.25E+09 - - - 1.3152 0.9964 221125_WJC_METTL3_EV_vs_WT_F02.09362.09362.2 0.071 14-Jul K.LLLTSTEK[136.11].S "sp|Q7L0Y3|TM10C_HUMAN,tr|C9JVB6|C9JVB6_HUMAN" 2 911.5419 0.59 11384 9362 2 911.54114 456.7782 tRNA methyltransferase 10 homolog C OS=Homo sapiens OX=9606 GN=TRMT10C PE=1 SV=2 6 2290.8 - 833507 - - - -0.8316 - 1.436 0.174 - 115.3 1 2 0 -0.0008 8 0 0 0 1.19E+08 2.02E+08 - - - 1.4173 0.9997 221125_WJC_METTL3_EV_vs_WT_F02.09370.09370.2 0.769 20-Nov K.VIMVGSGGVGK[136.11].S "sp|P11234|RALB_HUMAN,sp|P11233|RALA_HUMAN,tr|C9JPE8|C9JPE8_HUMAN,tr|H7C3P7|H7C3P7_HUMAN,tr|C9JYR1|C9JYR1_HUMAN,tr|F8WEQ6|F8WEQ6_HUMAN,tr|C9J6B1|C9J6B1_HUMAN,tr|C9JQB3|C9JQB3_HUMAN" 8 1010.5674 0.83 11385 9370 2 1010.567292 506.291 Ras-related protein Ral-B OS=Homo sapiens OX=9606 GN=RALB PE=1 SV=1 8.72 2292 - 351698 - - - -0.1088 - 1.82 0.408 - 309.6 1 2 0 -0.0001 11 0 0 0 5.78E+07 6.94E+07 - - - 3.6744 0.9974 221125_WJC_METTL3_EV_vs_WT_F02.09373.09373.2 0.00385 20-Sep K.VIMVGSGGVGK.S "sp|P11234|RALB_HUMAN,sp|P11233|RALA_HUMAN,tr|C9JPE8|C9JPE8_HUMAN,tr|H7C3P7|H7C3P7_HUMAN,tr|C9JYR1|C9JYR1_HUMAN,tr|F8WEQ6|F8WEQ6_HUMAN,tr|C9J6B1|C9J6B1_HUMAN,tr|C9JQB3|C9JQB3_HUMAN" 8 1002.5532 0.83 11387 9373 2 1002.549831 502.2839 Ras-related protein Ral-B OS=Homo sapiens OX=9606 GN=RALB PE=1 SV=1 8.72 2292.4 - 624640 - - - -3.3624 - 1.683 0.366 - 184.1 1 2 0 -0.0034 11 0 0 0 5.78E+07 7.00E+07 - - - 3.1515 0.9986 221125_WJC_METTL3_EV_vs_WT_F02.09388.09388.2 0.0502 12-Jul K.YGINNIR.E "sp|Q9Y285|SYFA_HUMAN,tr|K7ER00|K7ER00_HUMAN" 2 848.4505 0.69 11391 9388 2 848.449919 425.2325 Phenylalanine--tRNA ligase alpha subunit OS=Homo sapiens OX=9606 GN=FARSA PE=1 SV=3 8.75 2294.5 - 2.58E+06 - - - -0.627 - 1.422 0.263 - 165.1 1 2 0 -0.0005 7 0 0 0 8.94E+07 1.29E+08 - - - 2.0989 0.8463 221125_WJC_METTL3_EV_vs_WT_F02.09399.09399.2 4.46 12-Jun K.DIALEPK[136.11].E "sp|P82094|TMF1_HUMAN,tr|F8WF45|F8WF45_HUMAN,tr|A0A2R8Y7M0|A0A2R8Y7M0_HUMAN" 3 792.4473 1.4 11392 9399 2 792.444907 397.2309 TATA element modulatory factor OS=Homo sapiens OX=9606 GN=TMF1 PE=1 SV=2 4.37 2296.3 - 1.68E+06 - - - -2.9819 - 1.052 0.088 - 122.8 2 2 0 -0.0024 7 0 0 0 2.26E+08 1.62E+08 - - - -0.2836 0.9822 221125_WJC_METTL3_EV_vs_WT_F02.09400.09400.2 0.292 14-Jun K.FLQSYPGR.G sp|Q13948|CASP_HUMAN 1 966.4923 4.9 11393 9400 2 966.493547 484.2534 Protein CASP OS=Homo sapiens OX=9606 GN=CUX1 PE=1 SV=2 8.75 2296.4 - 345185 - - - 1.2737 - 1.285 0.096 - 113 1 2 0 0.0012 8 0 0 0 2.00E+07 4.07E+06 - - - 0.5059 0.9926 221125_WJC_METTL3_EV_vs_WT_F02.09404.09404.2 0.0579 16-Jun R.VLITENDVK.E sp|Q96S55|WRIP1_HUMAN 1 1029.5706 0.28 11394 9404 2 1029.569378 515.7926 ATPase WRNIP1 OS=Homo sapiens OX=9606 GN=WRNIP1 PE=1 SV=2 4.37 2297 - 297818 - - - -1.2122 - 1.186 0.201 - 89.3 1 2 0 -0.0012 9 0 0 0 8.26E+06 2.93E+07 - - - 1.0187 0.988 221125_WJC_METTL3_EV_vs_WT_F02.09406.09406.2 0.596 12-Jul R.TILLNTK[136.11].R "sp|P46940|IQGA1_HUMAN,tr|H0YLE8|H0YLE8_HUMAN" 2 809.5102 0.83 11395 9406 2 809.510558 405.7624 Ras GTPase-activating-like protein IQGAP1 OS=Homo sapiens OX=9606 GN=IQGAP1 PE=1 SV=1 8.41 2297.2 - 3.41E+06 - - - 0.4373 - 1.334 0.08 - 164.6 1 2 0 0.0004 7 0 0 0 1.23E+08 1.49E+08 - - - 0.5449 0.9063 221125_WJC_METTL3_EV_vs_WT_F02.09410.09410.2 8.31 12-Jul R.ALDVDYR[166.11].N "sp|Q9BZJ0|CRNL1_HUMAN,tr|Q5JY65|Q5JY65_HUMAN" 2 860.4268 1.69 11397 9410 2 860.426373 431.2207 Crooked neck-like protein 1 OS=Homo sapiens OX=9606 GN=CRNKL1 PE=1 SV=4 4.21 2297.6 - 695388 - - - -0.4405 - 1.021 0.007 - 176.7 1 2 0 -0.0004 7 0 0 0 4.68E+07 2.78E+07 - - - -0.8416 0.9828 221125_WJC_METTL3_EV_vs_WT_F02.09411.09411.2 0.0544 12-Jun R.ALDVDYR.N "sp|Q9BZJ0|CRNL1_HUMAN,tr|Q5JY65|Q5JY65_HUMAN" 2 850.4185 1.69 11398 9411 2 850.420175 426.2165 Crooked neck-like protein 1 OS=Homo sapiens OX=9606 GN=CRNKL1 PE=1 SV=4 4.21 2297.7 - 918736 - - - 1.9908 - 1.336 0.116 - 136.8 1 2 0 0.0017 7 0 0 0 4.68E+07 2.78E+07 - - - 0.8151 0.988 221125_WJC_METTL3_EV_vs_WT_F02.09415.09415.2 0.218 12-Jul K.DIALEPK.E "sp|P82094|TMF1_HUMAN,tr|F8WF45|F8WF45_HUMAN,tr|A0A2R8Y7M0|A0A2R8Y7M0_HUMAN" 3 784.4331 1.43 11400 9415 2 784.43149 393.2238 TATA element modulatory factor OS=Homo sapiens OX=9606 GN=TMF1 PE=1 SV=2 4.37 2298.2 - 3.22E+06 - - - -2.0142 - 1.099 0.229 - 167.9 1 2 0 -0.0016 7 0 0 0 2.25E+08 1.57E+08 - - - 1.031 0.9995 221125_WJC_METTL3_EV_vs_WT_F02.09416.09416.2 0.00925 16-Sep R.VLITENDVK[136.11].E sp|Q96S55|WRIP1_HUMAN 1 1037.5848 0.28 11401 9416 2 1037.584908 519.7997 ATPase WRNIP1 OS=Homo sapiens OX=9606 GN=WRNIP1 PE=1 SV=2 4.37 2298.3 - 866313 - - - 0.079 - 1.651 0.352 - 292 1 2 0 0.0001 9 0 0 0 8.26E+06 2.94E+07 - - - 3.0914 0.9995 221125_WJC_METTL3_EV_vs_WT_F02.09419.09419.2 0.0244 16-Nov K.VGAAEIISR[166.11].L sp|O75533|SF3B1_HUMAN 1 924.5268 1.38 11402 9419 2 924.525995 463.2707 Splicing factor 3B subunit 1 OS=Homo sapiens OX=9606 GN=SF3B1 PE=1 SV=3 5.97 2298.7 - 4.57E+06 - - - -0.8718 - 2.258 0.251 - 478.4 1 2 0 -0.0008 9 0 0 0 6.20E+08 4.49E+08 - - - 3.251 0.9983 221125_WJC_METTL3_EV_vs_WT_F02.09423.09423.2 0.025 16-Oct K.VGAAEIISR.L sp|O75533|SF3B1_HUMAN 1 914.5185 1.1 11404 9423 2 914.516026 458.2665 Splicing factor 3B subunit 1 OS=Homo sapiens OX=9606 GN=SF3B1 PE=1 SV=3 5.97 2299.2 - 6.48E+06 - - - -2.7391 - 1.955 0.285 - 274.5 1 2 0 -0.0025 9 0 0 0 6.35E+08 5.80E+08 - - - 3.0847 0.8643 221125_WJC_METTL3_EV_vs_WT_F02.09429.09429.2 6.35 12-Jun R.VWTSQLK.S "sp|Q16875|F263_HUMAN,sp|O60825|F262_HUMAN,tr|A0A1W2PR17|A0A1W2PR17_HUMAN,tr|Q5W015|Q5W015_HUMAN,tr|F2Z2I2|F2Z2I2_HUMAN,tr|H0Y483|H0Y483_HUMAN,tr|Q5VX20|Q5VX20_HUMAN" 7 860.4756 0.63 11408 9429 2 860.477388 431.2451 "6-phosphofructo-2-kinase\fructose-2,6-bisphosphatase 3 OS=Homo sapiens OX=9606 GN=PFKFB3 PE=1 SV=1" 8.72 2299.9 - 2.06E+06 - - - 2.0744 - 0.976 0.093 - 82.8 3 2 0 0.0018 7 0 0 0 5.89E+08 9.41E+08 - - - -0.5628 0.9353 221125_WJC_METTL3_EV_vs_WT_F02.09435.09435.2 1.26 14-Jul K.SLEATLGR[166.11].L sp|Q92665|RT31_HUMAN 1 855.469 0.84 11411 9435 2 855.466684 428.7418 "28S ribosomal protein S31, mitochondrial OS=Homo sapiens OX=9606 GN=MRPS31 PE=1 SV=3" 5.72 2300.7 - 946958 - - - -2.65 - 1.214 0.074 - 136.2 1 2 0 -0.0023 8 0 0 0 7.18E+07 8.55E+07 - - - 0.1717 0.9518 221125_WJC_METTL3_EV_vs_WT_F02.09437.09437.2 0.316 14-Jul K.LLNTAITR.A "sp|P42694|HELZ_HUMAN,tr|J3QS41|J3QS41_HUMAN" 2 900.5393 1.12 11413 9437 2 900.534999 451.2769 Probable helicase with zinc finger domain OS=Homo sapiens OX=9606 GN=HELZ PE=1 SV=2 9.75 2300.8 - 7.37E+06 - - - -4.7383 - 1.464 0.169 - 161.2 1 2 0 -0.0043 8 0 0 0 2.08E+08 1.86E+08 - - - 1.4375 0.9964 221125_WJC_METTL3_EV_vs_WT_F02.09438.09438.2 0.143 14-Jul K.SLEATLGR.L sp|Q92665|RT31_HUMAN 1 845.4607 0.77 11414 9438 2 845.460385 423.7376 "28S ribosomal protein S31, mitochondrial OS=Homo sapiens OX=9606 GN=MRPS31 PE=1 SV=3" 5.72 2300.9 - 2.05E+06 - - - -0.3501 - 1.6 0.121 - 159.8 1 2 0 -0.0003 8 0 0 0 3.83E+07 4.94E+07 - - - 1.3521 0.9991 221125_WJC_METTL3_EV_vs_WT_F02.09441.09441.2 0.0962 14-Aug K.QLIVGVNK[136.11].M "sp|Q05639|EF1A2_HUMAN,sp|P68104|EF1A1_HUMAN,sp|Q5VTE0|EF1A3_HUMAN,sp|P06276|CHLE_HUMAN,tr|A0A2R8Y488|A0A2R8Y488_HUMAN,tr|A0A7I2V659|A0A7I2V659_HUMAN,tr|A0A7I2V3H3|A0A7I2V3H3_HUMAN,tr|F8WF14|F8WF14_HUMAN,tr|A0A2U3TZH3|A0A2U3TZH3_HUMAN,tr|A0A7I2V5N4|A0A7I2V5N4_HUMAN,tr|A0A087WVQ9|A0A087WVQ9_HUMAN,tr|A0A087WV01|A0A087WV01_HUMAN,tr|F8WEX7|F8WEX7_HUMAN" 13 877.5477 0.37 11415 9441 2 877.546498 439.7811 Elongation factor 1-alpha 2 OS=Homo sapiens OX=9606 GN=EEF1A2 PE=1 SV=1 8.75 2301.3 - 2.49E+07 - - - -1.315 - 1.418 0.364 - 185.6 1 2 0 -0.0012 8 0 0 0 3.76E+08 1.02E+09 - - - 2.7825 0.9541 221125_WJC_METTL3_EV_vs_WT_F02.09447.09447.2 0.117 14-Jul T.LTDC[160.03]VVMR.D "sp|Q32P51|RA1L2_HUMAN,sp|P51991|ROA3_HUMAN,sp|P09651|ROA1_HUMAN,sp|P22626|ROA2_HUMAN,tr|A0A7I2YQN4|A0A7I2YQN4_HUMAN,tr|A0A7I2V4N0|A0A7I2V4N0_HUMAN,tr|A0A7I2V4N1|A0A7I2V4N1_HUMAN,tr|A0A7I2V5D8|A0A7I2V5D8_HUMAN,tr|F8W646|F8W646_HUMAN,tr|A0A7I2V2R3|A0A7I2V2R3_HUMAN,tr|A0A7I2V4I6|A0A7I2V4I6_HUMAN,tr|F8VZ49|F8VZ49_HUMAN,tr|A0A7I2V3R8|A0A7I2V3R8_HUMAN,tr|A0A087WUI2|A0A087WUI2_HUMAN,tr|A0A7I2V4S4|A0A7I2V4S4_HUMAN,tr|F8W6I7|F8W6I7_HUMAN,tr|A0A7I2V2L6|A0A7I2V2L6_HUMAN,tr|A0A7I2V4J6|A0A7I2V4J6_HUMAN,tr|A0A7I2V323|A0A7I2V323_HUMAN,tr|A0A7I2V3W0|A0A7I2V3W0_HUMAN,tr|A0A7I2V4G0|A0A7I2V4G0_HUMAN,tr|A0A7I2V402|A0A7I2V402_HUMAN,tr|A0A7I2V3P1|A0A7I2V3P1_HUMAN,tr|A0A7I2V3P7|A0A7I2V3P7_HUMAN" 24 992.4783 1.18 11418 9447 2 992.476349 497.2464 Heterogeneous nuclear ribonucleoprotein A1-like 2 OS=Homo sapiens OX=9606 GN=HNRNPA1L2 PE=2 SV=2 5.83 2302 - 5.61E+06 - - - -1.988 - 1.725 0.358 - 196.4 1 1 0 -0.002 8 0 0 0 4.51E+08 3.82E+08 - - - 3.3289 0.8841 221125_WJC_METTL3_EV_vs_WT_F02.09451.09451.2 0.0192 12-Jul R.WVVSAAH.C "sp|Q6UWY2|PRS57_HUMAN,tr|A0A0A0MR61|A0A0A0MR61_HUMAN" 2 768.3919 - 11420 9451 2 768.389783 385.2032 Serine protease 57 OS=Homo sapiens OX=9606 GN=PRSS57 PE=1 SV=2 6.74 2302.5 - 7.47E+06 - - - -2.72 - 1.473 0.349 - 170.4 1 1 0 -0.0021 7 0 0 0 - - - - - 2.8452 0.9977 221125_WJC_METTL3_EV_vs_WT_F02.09453.09453.2 0.123 14-Aug K.QLIVGVNK.M "sp|Q05639|EF1A2_HUMAN,sp|P68104|EF1A1_HUMAN,sp|Q5VTE0|EF1A3_HUMAN,sp|P06276|CHLE_HUMAN,tr|A0A2R8Y488|A0A2R8Y488_HUMAN,tr|A0A7I2V659|A0A7I2V659_HUMAN,tr|A0A7I2V3H3|A0A7I2V3H3_HUMAN,tr|F8WF14|F8WF14_HUMAN,tr|A0A2U3TZH3|A0A2U3TZH3_HUMAN,tr|A0A7I2V5N4|A0A7I2V5N4_HUMAN,tr|A0A087WVQ9|A0A087WVQ9_HUMAN,tr|A0A087WV01|A0A087WV01_HUMAN,tr|F8WEX7|F8WEX7_HUMAN" 13 869.5335 0.37 11421 9453 2 869.532361 435.774 Elongation factor 1-alpha 2 OS=Homo sapiens OX=9606 GN=EEF1A2 PE=1 SV=1 8.75 2302.7 - 9.72E+06 - - - -1.2547 - 1.327 0.275 - 198.5 1 2 0 -0.0011 8 0 0 0 3.76E+08 1.02E+09 - - - 1.9251 0.9948 221125_WJC_METTL3_EV_vs_WT_F02.09460.09460.2 0.358 12-Jun R.MPEC[160.03]YIR[166.11].G "sp|Q9Y4Z0|LSM4_HUMAN,tr|U3KQK1|U3KQK1_HUMAN,tr|V9GZ56|V9GZ56_HUMAN" 3 977.4338 1.3 11425 9460 2 977.434177 489.7242 U6 snRNA-associated Sm-like protein LSm4 OS=Homo sapiens OX=9606 GN=LSM4 PE=1 SV=1 5.75 2303.5 - 2.21E+06 - - - 0.356 - 1.204 0.2 - 132.5 1 2 0 0.0003 7 0 0 0 2.86E+08 2.20E+08 - - - 1.1063 0.853 221125_WJC_METTL3_EV_vs_WT_F02.09461.09461.2 3.69 14-Jul K.IPAVVVEK.D "sp|Q9Y6G9|DC1L1_HUMAN,tr|E9PHI6|E9PHI6_HUMAN" 2 853.5273 1.16 11426 9461 2 853.524972 427.7709 Cytoplasmic dynein 1 light intermediate chain 1 OS=Homo sapiens OX=9606 GN=DYNC1LI1 PE=1 SV=3 6 2303.6 - 936602 - - - -2.7322 - 1.193 0.045 - 71.2 4 2 0 -0.0023 8 0 0 0 6.01E+07 5.19E+07 - - - -0.3641 0.9939 221125_WJC_METTL3_EV_vs_WT_F02.09471.09471.2 4.68 12-Jun K.IITPLNK[136.11].D "sp|O75694|NU155_HUMAN,tr|E9PF10|E9PF10_HUMAN" 2 805.5153 2.76 11431 9471 2 805.514719 403.7649 Nuclear pore complex protein Nup155 OS=Homo sapiens OX=9606 GN=NUP155 PE=1 SV=1 8.75 2304.9 - 1.83E+06 - - - -0.7089 - 1.231 0.196 - 89.2 2 2 0 -0.0006 7 0 0 0 1.91E+08 6.92E+07 - - - 1.0125 0.9994 221125_WJC_METTL3_EV_vs_WT_F02.09475.09475.2 0.000962 14-Aug K.MLQEDELR[166.11].D sp|P84085|ARF5_HUMAN 1 1042.4993 1.11 11433 9475 2 1042.497492 522.2569 ADP-ribosylation factor 5 OS=Homo sapiens OX=9606 GN=ARF5 PE=1 SV=2 4.14 2305.4 - 356250 - - - -1.7007 - 1.46 0.445 - 286.3 1 2 0 -0.0018 8 0 0 0 1.61E+08 1.44E+08 - - - 3.4686 0.9246 221125_WJC_METTL3_EV_vs_WT_F02.09478.09478.2 0.024 12-Jul R.EEEMMIR.Q "sp|P23246|SFPQ_HUMAN,tr|H0Y9K7|H0Y9K7_HUMAN" 2 936.4045 0.75 11436 9478 2 936.397816 469.2095 "Splicing factor, proline- and glutamine-rich OS=Homo sapiens OX=9606 GN=SFPQ PE=1 SV=2" 4.25 2305.7 - 878878 - - - -7.1251 - 1.399 0.308 - 317.9 1 2 0 -0.0067 7 0 0 0 1.14E+08 1.52E+08 - - - 2.3777 0.9915 221125_WJC_METTL3_EV_vs_WT_F02.09481.09481.2 0.182 14-Jul K.MGSALLSR[166.11].F "sp|Q9UJA3|MCM8_HUMAN,tr|A0A494C100|A0A494C100_HUMAN" 2 843.4512 0.17 11437 9481 2 843.447489 422.7329 DNA helicase MCM8 OS=Homo sapiens OX=9606 GN=MCM8 PE=1 SV=2 9.5 2306.1 - 644082 - - - -4.3915 - 1.617 0.301 - 94 1 2 0 -0.0037 8 0 0 0 1.30E+07 7.82E+07 - - - 2.7124 0.9219 221125_WJC_METTL3_EV_vs_WT_F02.09486.09486.2 2.46 14-Sep R.VLAALQER[166.11].L "sp|Q99733|NP1L4_HUMAN,tr|E9PP22|E9PP22_HUMAN,tr|A8MXH2|A8MXH2_HUMAN,tr|E9PKI2|E9PKI2_HUMAN,tr|C9J1B1|C9J1B1_HUMAN,tr|C9J6D1|C9J6D1_HUMAN,tr|E9PJJ2|E9PJJ2_HUMAN,tr|E9PNW0|E9PNW0_HUMAN,tr|E9PKT8|E9PKT8_HUMAN,tr|E9PS34|E9PS34_HUMAN,tr|C9JZI7|C9JZI7_HUMAN,tr|E9PNJ7|E9PNJ7_HUMAN" 12 908.5319 1.05 11439 9486 2 908.528133 455.2732 Nucleosome assembly protein 1-like 4 OS=Homo sapiens OX=9606 GN=NAP1L4 PE=1 SV=1 5.97 2306.8 - 2.68E+06 - - - -4.1308 - 1.552 0.053 - 322.9 1 2 0 -0.0038 8 0 0 0 2.40E+08 2.28E+08 - - - 0.7569 0.9978 221125_WJC_METTL3_EV_vs_WT_F02.09487.09487.2 1.73 14-Sep K.LC[160.03]TVATLR.E "sp|P02768|ALBU_HUMAN,tr|A0A087WWT3|A0A087WWT3_HUMAN,tr|H7C013|H7C013_HUMAN,tr|A0A0C4DGB6|A0A0C4DGB6_HUMAN" 4 932.5113 514.23 11440 9487 2 932.508641 467.2629 Albumin OS=Homo sapiens OX=9606 GN=ALB PE=1 SV=2 8.25 2306.8 - 1.53E+06 - - - -2.8911 - 1.966 0.253 - 297.6 1 2 0 -0.0027 8 0 0 0 3.57E+08 6.94E+05 - - - 2.9476 0.9838 221125_WJC_METTL3_EV_vs_WT_F02.09492.09492.2 0.00707 14-Aug T.LTDC[160.03]VVMR[166.11].D "sp|Q32P51|RA1L2_HUMAN,sp|P51991|ROA3_HUMAN,sp|P09651|ROA1_HUMAN,sp|P22626|ROA2_HUMAN,tr|A0A7I2YQN4|A0A7I2YQN4_HUMAN,tr|A0A7I2V4N0|A0A7I2V4N0_HUMAN,tr|A0A7I2V4N1|A0A7I2V4N1_HUMAN,tr|A0A7I2V5D8|A0A7I2V5D8_HUMAN,tr|F8W646|F8W646_HUMAN,tr|A0A7I2V2R3|A0A7I2V2R3_HUMAN,tr|A0A7I2V4I6|A0A7I2V4I6_HUMAN,tr|F8VZ49|F8VZ49_HUMAN,tr|A0A7I2V3R8|A0A7I2V3R8_HUMAN,tr|A0A087WUI2|A0A087WUI2_HUMAN,tr|A0A7I2V4S4|A0A7I2V4S4_HUMAN,tr|F8W6I7|F8W6I7_HUMAN,tr|A0A7I2V2L6|A0A7I2V2L6_HUMAN,tr|A0A7I2V4J6|A0A7I2V4J6_HUMAN,tr|A0A7I2V323|A0A7I2V323_HUMAN,tr|A0A7I2V3W0|A0A7I2V3W0_HUMAN,tr|A0A7I2V4G0|A0A7I2V4G0_HUMAN,tr|A0A7I2V402|A0A7I2V402_HUMAN,tr|A0A7I2V3P1|A0A7I2V3P1_HUMAN,tr|A0A7I2V3P7|A0A7I2V3P7_HUMAN" 24 1002.4866 1.18 11443 9492 2 1002.485114 502.2506 Heterogeneous nuclear ribonucleoprotein A1-like 2 OS=Homo sapiens OX=9606 GN=HNRNPA1L2 PE=2 SV=2 5.83 2307.4 - 9.20E+06 - - - -1.4743 - 1.806 0.462 - 276.3 1 1 0 -0.0015 8 0 0 0 4.51E+08 3.82E+08 - - - 4.2356 0.9092 221125_WJC_METTL3_EV_vs_WT_F02.09501.09501.2 0.193 14-Aug K.VIPELNGK.L "sp|P04406|G3P_HUMAN,tr|E7EUT5|E7EUT5_HUMAN" 2 868.5018 1.08 11446 9501 2 868.497573 435.2582 Glyceraldehyde-3-phosphate dehydrogenase OS=Homo sapiens OX=9606 GN=GAPDH PE=1 SV=3 5.97 2308.6 - 5.39E+06 - - - -4.8877 - 1.165 0.206 - 189.3 1 2 0 -0.0042 8 0 0 0 1.10E+10 1.02E+10 - - - 1.0218 0.9996 221125_WJC_METTL3_EV_vs_WT_F02.09505.09505.2 0.0335 14-Aug K.VIPELNGK[136.11].L "sp|P04406|G3P_HUMAN,tr|E7EUT5|E7EUT5_HUMAN" 2 876.516 1.08 11448 9505 2 876.516179 439.2653 Glyceraldehyde-3-phosphate dehydrogenase OS=Homo sapiens OX=9606 GN=GAPDH PE=1 SV=3 5.97 2309.1 - 9.21E+06 - - - 0.1837 - 1.712 0.347 - 212.5 1 2 0 0.0002 8 0 0 0 1.10E+10 1.02E+10 - - - 3.2255 0.9993 221125_WJC_METTL3_EV_vs_WT_F02.09506.09506.2 0.0326 14-Aug K.LTVLSEER[166.11].A "sp|Q13813|SPTN1_HUMAN,tr|A0A0D9SF54|A0A0D9SF54_HUMAN,tr|A0A0D9SGF6|A0A0D9SGF6_HUMAN" 3 955.5214 2.31 11449 9506 2 955.52085 478.768 "Spectrin alpha chain, non-erythrocytic 1 OS=Homo sapiens OX=9606 GN=SPTAN1 PE=1 SV=3" 4.53 2309.2 - 855948 - - - -0.5557 - 1.786 0.261 - 267.7 1 2 0 -0.0005 8 0 0 0 1.40E+08 6.05E+07 - - - 2.7178 0.9989 221125_WJC_METTL3_EV_vs_WT_F02.09509.09509.2 0.037 16-Aug R.QTVAVGVIK[136.11].N "sp|Q05639|EF1A2_HUMAN,sp|P68104|EF1A1_HUMAN,sp|Q5VTE0|EF1A3_HUMAN,tr|A0A7I2V659|A0A7I2V659_HUMAN,tr|A0A2U3TZH3|A0A2U3TZH3_HUMAN,tr|A0A087WVQ9|A0A087WVQ9_HUMAN" 6 921.5739 0.39 11450 9509 2 921.573085 461.7942 Elongation factor 1-alpha 2 OS=Homo sapiens OX=9606 GN=EEF1A2 PE=1 SV=1 8.75 2309.6 - 2.57E+06 - - - -0.8485 - 1.562 0.282 - 267 1 2 0 -0.0008 9 0 0 0 7.49E+07 1.91E+08 - - - 2.4138 0.9964 221125_WJC_METTL3_EV_vs_WT_F02.09513.09513.2 0.0723 12-Jun K.VLVDMSR[166.11].V "sp|P78371|TCPB_HUMAN,tr|F8VQ14|F8VQ14_HUMAN,tr|F5GWF6|F5GWF6_HUMAN" 3 828.4403 0.43 11452 9513 2 828.439698 415.2274 T-complex protein 1 subunit beta OS=Homo sapiens OX=9606 GN=CCT2 PE=1 SV=4 5.81 2310 - 6.36E+07 - - - -0.7194 - 1.13 0.268 - 143.3 1 2 0 -0.0006 7 0 0 0 1.95E+09 4.55E+09 - - - 1.4075 0.9932 221125_WJC_METTL3_EV_vs_WT_F02.09520.09520.2 0.0556 16-Jul R.QTVAVGVIK.N "sp|Q05639|EF1A2_HUMAN,sp|P68104|EF1A1_HUMAN,sp|Q5VTE0|EF1A3_HUMAN,tr|A0A7I2V659|A0A7I2V659_HUMAN,tr|A0A2U3TZH3|A0A2U3TZH3_HUMAN,tr|A0A087WVQ9|A0A087WVQ9_HUMAN" 6 913.5597 0.39 11454 9520 2 913.557833 457.7871 Elongation factor 1-alpha 2 OS=Homo sapiens OX=9606 GN=EEF1A2 PE=1 SV=1 8.75 2311 - 1.60E+06 - - - -2.0075 - 1.284 0.227 - 106.4 1 2 0 -0.0018 9 0 0 0 7.49E+07 1.91E+08 - - - 1.4403 0.9959 221125_WJC_METTL3_EV_vs_WT_F02.09522.09522.2 0.11 20-Sep K.LLC[160.03]GGGIAADR[166.11].G "sp|P05091|ALDH2_HUMAN,tr|S4R3S4|S4R3S4_HUMAN" 2 1111.5683 0.99 11456 9522 2 1111.566803 556.7915 "Aldehyde dehydrogenase, mitochondrial OS=Homo sapiens OX=9606 GN=ALDH2 PE=1 SV=2" 5.83 2311.3 - 337257 - - - -1.3899 - 1.493 0.189 - 161.2 1 2 0 -0.0015 11 0 0 0 9.38E+06 9.49E+06 - - - 1.5207 0.9903 221125_WJC_METTL3_EV_vs_WT_F02.09523.09523.2 0.0131 16-Aug R.LEGEIATYR.H sp|O76013|KRT36_HUMAN 1 1050.5346 0.47 11457 9523 2 1050.539273 526.2746 "Keratin, type I cuticular Ha6 OS=Homo sapiens OX=9606 GN=KRT36 PE=1 SV=1" 4.53 2311.4 - 145460 - - - 4.472 - 1.589 0.309 - 128.1 1 2 0 0.0047 9 0 0 0 1.92E+07 4.08E+07 - - - 2.6616 0.9993 221125_WJC_METTL3_EV_vs_WT_F02.09525.09525.2 0.012 12-Jul K.VLVDMSR.V "sp|P78371|TCPB_HUMAN,tr|F8VQ14|F8VQ14_HUMAN,tr|F5GWF6|F5GWF6_HUMAN" 3 818.432 0.43 11458 9525 2 818.432074 410.2233 T-complex protein 1 subunit beta OS=Homo sapiens OX=9606 GN=CCT2 PE=1 SV=4 5.81 2311.6 - 3.67E+07 - - - 0.0611 - 1.386 0.356 - 253.8 1 2 0 0.0001 7 0 0 0 1.96E+09 4.55E+09 - - - 2.7047 0.997 221125_WJC_METTL3_EV_vs_WT_F02.09532.09532.2 0.0797 12-Jul K.VLDEFSK.Q "sp|O15498|YKT6_HUMAN,tr|A0A7I2V4L6|A0A7I2V4L6_HUMAN,tr|A0A7I2V3V7|A0A7I2V3V7_HUMAN,tr|A0A7I2V3A1|A0A7I2V3A1_HUMAN" 4 836.428 1.89 11461 9532 2 836.426092 419.2213 Synaptobrevin homolog YKT6 OS=Homo sapiens OX=9606 GN=YKT6 PE=1 SV=1 4.37 2312.5 - 4.80E+06 - - - -2.262 - 1.349 0.305 - 145.3 1 2 0 -0.0019 7 0 0 0 1.99E+08 1.05E+08 - - - 2.2417 0.9993 221125_WJC_METTL3_EV_vs_WT_F02.09534.09534.2 0.161 14-Aug R.LVGDVIQR.F "sp|O00746|NDKM_HUMAN,tr|Q4TT34|Q4TT34_HUMAN,tr|A0A087WVT9|A0A087WVT9_HUMAN,tr|H0Y6J0|H0Y6J0_HUMAN,tr|F2Z2X0|F2Z2X0_HUMAN" 5 898.5236 1.88 11462 9534 2 898.52295 450.2691 "Nucleoside diphosphate kinase, mitochondrial OS=Homo sapiens OX=9606 GN=NME4 PE=1 SV=1" 5.84 2312.7 - 6.79E+06 - - - -0.7412 - 1.424 0.36 - 190.7 1 2 0 -0.0007 8 0 0 0 1.68E+10 8.93E+09 - - - 2.7658 0.9988 221125_WJC_METTL3_EV_vs_WT_F02.09538.09538.2 0.0192 12-Jul R.EEEMMIR[166.11].Q "sp|P23246|SFPQ_HUMAN,tr|H0Y9K7|H0Y9K7_HUMAN" 2 946.4128 0.74 11464 9538 2 946.411242 474.2137 "Splicing factor, proline- and glutamine-rich OS=Homo sapiens OX=9606 GN=SFPQ PE=1 SV=2" 4.25 2313.1 - 2.84E+06 - - - -1.6018 - 1.283 0.381 - 266.7 1 2 0 -0.0015 7 0 0 0 1.14E+08 1.55E+08 - - - 2.6442 0.9987 221125_WJC_METTL3_EV_vs_WT_F02.09544.09544.2 0.0172 14-Aug K.LTVLSEER.A "sp|Q13813|SPTN1_HUMAN,tr|A0A0D9SF54|A0A0D9SF54_HUMAN,tr|A0A0D9SGF6|A0A0D9SGF6_HUMAN" 3 945.5131 1.78 11467 9544 2 945.511761 473.7638 "Spectrin alpha chain, non-erythrocytic 1 OS=Homo sapiens OX=9606 GN=SPTAN1 PE=1 SV=3" 4.53 2313.8 - 2.70E+06 - - - -1.4278 - 1.522 0.293 - 300.2 1 2 0 -0.0014 8 0 0 0 1.08E+08 6.05E+07 - - - 2.4715 0.7792 221125_WJC_METTL3_EV_vs_WT_F02.09546.09546.2 2.19 12-May R.VLNLTER.Q sp|P31274|HXC9_HUMAN 1 843.4814 2.58 11469 9546 2 843.479622 422.748 Homeobox protein Hox-C9 OS=Homo sapiens OX=9606 GN=HOXC9 PE=1 SV=3 5.97 2313.9 - 2.97E+06 - - - -2.1281 - 0.996 0.004 - 69 1 2 0 -0.0018 7 0 0 0 2.25E+08 8.71E+07 - - - -0.9427 0.9998 221125_WJC_METTL3_EV_vs_WT_F02.09547.09547.2 5.51E-05 16-Oct R.MYAALGDPK[136.11].A sp|P78527|PRKDC_HUMAN 1 972.483 1.72 11470 9547 2 972.482162 487.2488 DNA-dependent protein kinase catalytic subunit OS=Homo sapiens OX=9606 GN=PRKDC PE=1 SV=3 5.59 2314 - 916378 - - - -0.8648 - 1.74 0.479 - 336.7 1 2 0 -0.0008 9 0 0 0 8.46E+07 4.91E+07 - - - 4.181 0.9991 221125_WJC_METTL3_EV_vs_WT_F02.09551.09551.2 0.00266 16-Sep R.NVVVVDGVR[166.11].T "sp|P55084|ECHB_HUMAN,tr|C9K0M0|C9K0M0_HUMAN,tr|C9JE81|C9JE81_HUMAN,tr|F5GZQ3|F5GZQ3_HUMAN,tr|B5MD38|B5MD38_HUMAN,tr|C9JEY0|C9JEY0_HUMAN" 6 965.5534 0.88 11471 9551 2 965.5513 483.784 "Trifunctional enzyme subunit beta, mitochondrial OS=Homo sapiens OX=9606 GN=HADHB PE=1 SV=3" 5.84 2314.5 - 2.31E+06 - - - -2.1231 - 1.654 0.384 - 328.7 1 2 0 -0.002 9 0 0 0 1.65E+08 1.88E+08 - - - 3.3324 0.9991 221125_WJC_METTL3_EV_vs_WT_F02.09556.09556.2 0.00992 16-Jul R.NVVVVDGVR.T "sp|P55084|ECHB_HUMAN,tr|C9K0M0|C9K0M0_HUMAN,tr|C9JE81|C9JE81_HUMAN,tr|F5GZQ3|F5GZQ3_HUMAN,tr|B5MD38|B5MD38_HUMAN,tr|C9JEY0|C9JEY0_HUMAN" 6 955.5451 0.89 11473 9556 2 955.543846 478.7798 "Trifunctional enzyme subunit beta, mitochondrial OS=Homo sapiens OX=9606 GN=HADHB PE=1 SV=3" 5.84 2315.1 - 1.35E+06 - - - -1.2914 - 1.579 0.323 - 178.7 1 2 0 -0.0012 9 0 0 0 1.64E+08 1.86E+08 - - - 2.7478 0.9986 221125_WJC_METTL3_EV_vs_WT_F02.09565.09565.2 0.00174 16-Jul K.IVPTVYEDK[136.11].S sp|Q969X5|ERGI1_HUMAN 1 1070.5739 0.85 11476 9565 2 1070.571043 536.2942 Endoplasmic reticulum-Golgi intermediate compartment protein 1 OS=Homo sapiens OX=9606 GN=ERGIC1 PE=1 SV=1 4.37 2316.4 - 748006 - - - -2.6939 - 1.304 0.472 - 174.3 1 2 0 -0.0029 9 0 0 0 5.93E+07 7.01E+07 - - - 3.2942 0.9954 221125_WJC_METTL3_EV_vs_WT_F02.09568.09568.2 0.588 12-Aug R.VLNLTER[166.11].Q sp|P31274|HXC9_HUMAN 1 853.4897 2.48 11477 9568 2 853.488098 427.7521 Homeobox protein Hox-C9 OS=Homo sapiens OX=9606 GN=HOXC9 PE=1 SV=3 5.97 2316.8 - 2.84E+06 - - - -1.8618 - 1.587 0.158 - 203.2 1 2 0 -0.0016 7 0 0 0 2.16E+08 8.70E+07 - - - 1.6709 0.9993 221125_WJC_METTL3_EV_vs_WT_F02.09573.09573.2 0.0176 16-Sep K.IVPTVYEDK.S sp|Q969X5|ERGI1_HUMAN 1 1062.5597 0.93 11480 9573 2 1062.558077 532.2871 Endoplasmic reticulum-Golgi intermediate compartment protein 1 OS=Homo sapiens OX=9606 GN=ERGIC1 PE=1 SV=1 4.37 2317.4 - 1.88E+06 - - - -1.5529 - 1.432 0.41 - 261.5 1 2 0 -0.0016 9 0 0 0 5.55E+07 5.96E+07 - - - 3.1076 0.9979 221125_WJC_METTL3_EV_vs_WT_F02.09576.09576.2 0.615 12-Jul R.MGLSMER.M "sp|P52272|HNRPM_HUMAN,tr|M0R2I7|M0R2I7_HUMAN,tr|A0A087X0X3|A0A087X0X3_HUMAN,tr|M0QZM1|M0QZM1_HUMAN" 4 822.3728 1.54 11481 9576 2 822.371069 412.1937 Heterogeneous nuclear ribonucleoprotein M OS=Homo sapiens OX=9606 GN=HNRNPM PE=1 SV=3 5.75 2317.7 - 3.09E+07 - - - -2.0976 - 1.609 0.258 - 191 1 2 0 -0.0017 7 0 0 0 1.79E+09 1.16E+09 - - - 2.4531 0.8935 221125_WJC_METTL3_EV_vs_WT_F02.09581.09581.2 19.5 12-Jun R.LAADDFR.T "sp|Q04695|K1C17_HUMAN,sp|P13645|K1C10_HUMAN,sp|O76015|KRT38_HUMAN,sp|Q2M2I5|K1C24_HUMAN,sp|Q15323|K1H1_HUMAN,sp|P02533|K1C14_HUMAN,sp|P05783|K1C18_HUMAN,sp|P08727|K1C19_HUMAN,sp|P08779|K1C16_HUMAN,sp|Q7Z3Y7|K1C28_HUMAN,sp|Q14532|K1H2_HUMAN,sp|P19012|K1C15_HUMAN,sp|O76013|KRT36_HUMAN,sp|Q14525|KT33B_HUMAN,sp|Q92764|KRT35_HUMAN,sp|O76014|KRT37_HUMAN,sp|P13646|K1C13_HUMAN,tr|F8VZY9|F8VZY9_HUMAN,tr|K7EPJ9|K7EPJ9_HUMAN,tr|C9JM50|C9JM50_HUMAN,tr|A0A1B0GVI3|A0A1B0GVI3_HUMAN,tr|K7EMD9|K7EMD9_HUMAN,tr|F5GWP8|F5GWP8_HUMAN,tr|K7ERE3|K7ERE3_HUMAN,tr|C4AM86|C4AM86_HUMAN" 25 806.3923 24.29 11483 9581 2 806.38906 404.2034 "Keratin, type I cytoskeletal 17 OS=Homo sapiens OX=9606 GN=KRT17 PE=1 SV=2" 4.21 2318.4 - 1.76E+06 - - - -3.977 - 1.203 0.112 - 137.3 1 2 0 -0.0032 7 0 0 0 9.97E+07 4.11E+06 - - - 0.4528 0.9987 221125_WJC_METTL3_EV_vs_WT_F02.09583.09583.2 2.76 12-Aug R.MGLSMER[166.11].M "sp|P52272|HNRPM_HUMAN,tr|M0R2I7|M0R2I7_HUMAN,tr|A0A087X0X3|A0A087X0X3_HUMAN,tr|M0QZM1|M0QZM1_HUMAN" 4 832.3811 1.54 11484 9583 2 832.379265 417.1978 Heterogeneous nuclear ribonucleoprotein M OS=Homo sapiens OX=9606 GN=HNRNPM PE=1 SV=3 5.75 2318.6 - 3.03E+07 - - - -2.1613 - 1.957 0.246 - 272.4 1 2 0 -0.0018 7 0 0 0 1.79E+09 1.16E+09 - - - 2.9848 0.9964 221125_WJC_METTL3_EV_vs_WT_F02.09587.09587.2 1.47 12-Jul R.LNVAITR[166.11].A "sp|P51530|DNA2_HUMAN,sp|Q9Y4D8|HECD4_HUMAN,sp|Q92900|RENT1_HUMAN,tr|A0A804HJX8|A0A804HJX8_HUMAN,tr|A0A494C150|A0A494C150_HUMAN,tr|F8VWT9|F8VWT9_HUMAN,tr|F8VR31|F8VR31_HUMAN,tr|J3KPF0|J3KPF0_HUMAN,tr|H0Y455|H0Y455_HUMAN" 9 795.4842 1.06 11486 9587 2 795.483267 398.7494 DNA replication ATP-dependent helicase\nuclease DNA2 OS=Homo sapiens OX=9606 GN=DNA2 PE=1 SV=3 9.75 2319.1 - 3.24E+06 - - - -1.1829 - 1.654 0.122 - 154.8 1 2 0 -0.0009 7 0 0 0 1.04E+08 9.80E+07 - - - 1.5362 0.9975 221125_WJC_METTL3_EV_vs_WT_F02.09588.09588.2 3.27 12-Jul K.C[160.03]GLVIGR.G "sp|Q92945|FUBP2_HUMAN,tr|M0R3J3|M0R3J3_HUMAN,tr|M0R0C6|M0R0C6_HUMAN,tr|A0A087WTP3|A0A087WTP3_HUMAN" 4 773.4218 0.14 11487 9588 2 773.419362 387.7182 Far upstream element-binding protein 2 OS=Homo sapiens OX=9606 GN=KHSRP PE=1 SV=4 8.25 2319.1 - 2.38E+06 - - - -3.1445 - 1.704 0.311 - 228.2 1 2 0 -0.0024 7 0 0 0 2.58E+08 1.80E+09 - - - 3.0261 0.9368 221125_WJC_METTL3_EV_vs_WT_F02.09593.09593.2 1 14-Jul R.LVQGSILK.K sp|P12004|PCNA_HUMAN 1 856.5382 1.04 11488 9593 2 856.536312 429.2764 Proliferating cell nuclear antigen OS=Homo sapiens OX=9606 GN=PCNA PE=1 SV=1 8.75 2319.9 - 1.58E+06 - - - -2.2077 - 1.162 0.066 - 117.9 1 2 0 -0.0019 8 0 0 0 7.19E+07 6.88E+07 - - - -0.0193 0.9977 221125_WJC_METTL3_EV_vs_WT_F02.09600.09600.2 2.08 14-Aug R.GMTVEGLK[136.11].Q "sp|P07814|SYEP_HUMAN,tr|V9GYZ6|V9GYZ6_HUMAN" 2 841.4459 0.82 11491 9600 2 841.44436 421.7302 Bifunctional glutamate\proline--tRNA ligase OS=Homo sapiens OX=9606 GN=EPRS1 PE=1 SV=5 6 2320.7 - 2.92E+06 - - - -1.8171 - 1.493 0.266 - 236.8 1 2 0 -0.0015 8 0 0 0 9.51E+07 1.16E+08 - - - 2.214 0.9487 221125_WJC_METTL3_EV_vs_WT_F02.09614.09614.2 0.296 16-May R.AVLC[160.03]PPPVK.K "sp|P63000|RAC1_HUMAN,sp|P60763|RAC3_HUMAN" 2 979.5525 1.02 11494 9614 2 979.549522 490.7835 Ras-related C3 botulinum toxin substrate 1 OS=Homo sapiens OX=9606 GN=RAC1 PE=1 SV=1 8.27 2322.8 - 256908 - - - -3.0136 - 1.283 0.148 - 70.8 6 2 0 -0.003 9 0 0 0 1.24E+07 1.21E+07 - - - 0.5066 0.9899 221125_WJC_METTL3_EV_vs_WT_F02.09629.09629.2 0.114 16-Jul K.LVSTSVTIR[166.11].E sp|Q709C8|VP13C_HUMAN 1 984.5843 0.52 11501 9629 2 984.587374 493.2994 Vacuolar protein sorting-associated protein 13C OS=Homo sapiens OX=9606 GN=VPS13C PE=1 SV=1 9.75 2324.6 - 288760 - - - 3.1059 - 1.384 0.242 - 135.4 1 2 0 0.0031 9 0 0 0 7.51E+06 1.45E+07 - - - 1.7676 0.9956 221125_WJC_METTL3_EV_vs_WT_F02.09638.09638.2 0.827 12-Jul R.ISLATPR[166.11].Q "sp|Q8NFP9|NBEA_HUMAN,tr|Q5T321|Q5T321_HUMAN,tr|A0A0D9SF28|A0A0D9SF28_HUMAN" 3 766.4577 0.75 11504 9638 2 766.458054 384.2361 Neurobeachin OS=Homo sapiens OX=9606 GN=NBEA PE=1 SV=3 9.75 2325.8 - 2.26E+06 - - - 0.5167 - 1.544 0.132 - 112.8 2 2 0 0.0004 7 0 0 0 2.18E+08 2.91E+08 - - - 1.2577 0.9646 221125_WJC_METTL3_EV_vs_WT_F02.09639.09639.2 1.78 12-Jun R.VQEVLLK[136.11].A "sp|Q9Y4L1|HYOU1_HUMAN,tr|A0A087WWI4|A0A087WWI4_HUMAN,tr|K7EQK2|K7EQK2_HUMAN,tr|A0A494C039|A0A494C039_HUMAN,tr|A0A087X054|A0A087X054_HUMAN,tr|E9PJ21|E9PJ21_HUMAN" 6 835.5259 0.99 11505 9639 2 835.524495 418.7702 Hypoxia up-regulated protein 1 OS=Homo sapiens OX=9606 GN=HYOU1 PE=1 SV=1 5.97 2325.9 - 1.30E+06 - - - -1.6265 - 1.299 0.062 - 89.5 3 2 0 -0.0014 7 0 0 0 5.48E+07 5.57E+07 - - - 0.1143 0.9932 221125_WJC_METTL3_EV_vs_WT_F02.09640.09640.2 0.764 16-Jun K.LVSTSVTIR.E sp|Q709C8|VP13C_HUMAN 1 974.576 0.52 11506 9640 2 974.574417 488.2953 Vacuolar protein sorting-associated protein 13C OS=Homo sapiens OX=9606 GN=VPS13C PE=1 SV=1 9.75 2326 - 389133 - - - -1.6715 - 1.249 0.216 - 117.6 1 2 0 -0.0016 9 0 0 0 7.51E+06 1.45E+07 - - - 1.2791 0.999 221125_WJC_METTL3_EV_vs_WT_F02.09651.09651.2 0.0112 14-Jul K.LPASFDAR.E "sp|P07858|CATB_HUMAN,tr|E9PLY3|E9PLY3_HUMAN,tr|A0A7I2V4Z9|A0A7I2V4Z9_HUMAN,tr|A0A7I2V440|A0A7I2V440_HUMAN,tr|E9PQM1|E9PQM1_HUMAN,tr|E9PSG5|E9PSG5_HUMAN,tr|A0A7I2V4S6|A0A7I2V4S6_HUMAN,tr|A0A7I2V668|A0A7I2V668_HUMAN,tr|A0A7P0NGZ6|A0A7P0NGZ6_HUMAN,tr|A0A7I2YQK9|A0A7I2YQK9_HUMAN,tr|E9PKQ7|E9PKQ7_HUMAN,tr|E9PHZ5|E9PHZ5_HUMAN,tr|E9PR21|E9PR21_HUMAN,tr|E9PNL5|E9PNL5_HUMAN,tr|A0A7I2V2J1|A0A7I2V2J1_HUMAN,tr|E9PCB3|E9PCB3_HUMAN,tr|A0A7I2V302|A0A7I2V302_HUMAN,tr|E9PS78|E9PS78_HUMAN" 18 875.4501 4.89 11511 9651 2 875.449411 438.7323 Cathepsin B OS=Homo sapiens OX=9606 GN=CTSB PE=1 SV=3 5.84 2327.4 - 1.51E+06 - - - -0.8064 - 1.416 0.32 - 128.1 1 2 0 -0.0007 8 0 0 0 1.06E+08 2.16E+07 - - - 2.4534 0.9989 221125_WJC_METTL3_EV_vs_WT_F02.09652.09652.2 0.0887 16-Aug R.VYAEVNSLR.S "sp|P19784|CSK22_HUMAN,tr|H3BNI9|H3BNI9_HUMAN" 2 1049.5506 1.02 11512 9652 2 1049.550016 525.7826 Casein kinase II subunit alpha' OS=Homo sapiens OX=9606 GN=CSNK2A2 PE=1 SV=1 5.97 2327.5 - 958495 - - - -0.5174 - 1.43 0.307 - 215.1 1 2 0 -0.0005 9 0 0 0 1.22E+08 1.20E+08 - - - 2.3431 0.9839 221125_WJC_METTL3_EV_vs_WT_F02.09659.09659.2 0.000311 16-Jul R.NPEAALSPT.F "sp|Q86U44|MTA70_HUMAN,tr|B4E349|B4E349_HUMAN,tr|F5H6D8|F5H6D8_HUMAN,tr|B4DTN4|B4DTN4_HUMAN" 4 898.4396 - 11515 9659 2 898.439504 450.2271 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 4 2328.4 - 3.14E+07 - - - -0.1202 - 1.468 0.478 - 133.9 1 1 0 -0.0001 9 0 0 0 - - - - - 3.6821 0.9802 221125_WJC_METTL3_EV_vs_WT_F02.09665.09665.2 3.05 12-Jun K.QVAPLLK[136.11].S "sp|Q13948|CASP_HUMAN,sp|P39880|CUX1_HUMAN,tr|A0A2R8Y852|A0A2R8Y852_HUMAN,tr|A0A2R8YDI1|A0A2R8YDI1_HUMAN" 4 775.5047 1.11 11518 9665 2 775.504251 388.7596 Protein CASP OS=Homo sapiens OX=9606 GN=CUX1 PE=1 SV=2 8.75 2329.2 - 4.08E+06 - - - -0.6112 - 1.092 0.119 - 161.4 1 2 0 -0.0005 7 0 0 0 3.68E+08 3.31E+08 - - - 0.1987 0.9888 221125_WJC_METTL3_EV_vs_WT_F02.09666.09666.2 0.127 14-Jul R.LISLAAQK[136.11].F "sp|Q12962|TAF10_HUMAN,tr|A0A087WWP5|A0A087WWP5_HUMAN" 2 850.5368 0.85 11519 9666 2 850.535476 426.2757 Transcription initiation factor TFIID subunit 10 OS=Homo sapiens OX=9606 GN=TAF10 PE=1 SV=1 8.75 2329.3 - 1.03E+06 - - - -1.5014 - 1.421 0.1 - 115.6 1 2 0 -0.0013 8 0 0 0 9.17E+07 1.08E+08 - - - 0.8389 0.977 221125_WJC_METTL3_EV_vs_WT_F02.09667.09667.2 1.11 16-Jun R.IIPGGIADR[166.11].H "sp|Q9NUP9|LIN7C_HUMAN,tr|G3V1D4|G3V1D4_HUMAN" 2 920.5319 11.62 11520 9667 2 920.531843 461.2732 Protein lin-7 homolog C OS=Homo sapiens OX=9606 GN=LIN7C PE=1 SV=1 5.84 2329.3 - 1.08E+06 - - - -0.0467 - 1.152 0.112 - 83.7 3 2 0 0 9 0 0 0 1.08E+09 9.29E+07 - - - 0.0645 0.9902 221125_WJC_METTL3_EV_vs_WT_F02.09670.09670.2 0.0595 16-Jun K.TIAPALVSK[136.11].K "sp|P06733|ENOA_HUMAN,tr|K7ERS8|K7ERS8_HUMAN,tr|K7EM90|K7EM90_HUMAN,tr|A0A2R8Y879|A0A2R8Y879_HUMAN,tr|A0A2R8Y6I8|A0A2R8Y6I8_HUMAN,tr|A0A2R8YEM5|A0A2R8YEM5_HUMAN" 6 906.563 1.44 11521 9670 2 906.56365 454.2888 Alpha-enolase OS=Homo sapiens OX=9606 GN=ENO1 PE=1 SV=2 8.41 2329.7 - 3.91E+06 - - - 0.7523 - 1.339 0.146 - 107.2 3 2 0 0.0007 9 0 0 0 2.19E+09 1.52E+09 - - - 0.7506 0.989 221125_WJC_METTL3_EV_vs_WT_F02.09684.09684.2 0.243 12-Jul K.IISLDAK.L "sp|P07814|SYEP_HUMAN,tr|V9GYZ6|V9GYZ6_HUMAN" 2 758.4538 0.58 11531 9684 2 758.453184 380.2342 Bifunctional glutamate\proline--tRNA ligase OS=Homo sapiens OX=9606 GN=EPRS1 PE=1 SV=5 5.84 2331.2 - 5.17E+06 - - - -0.8188 - 1.457 0.054 - 142.5 1 2 0 -0.0006 7 0 0 0 2.42E+08 4.20E+08 - - - 0.6322 0.9705 221125_WJC_METTL3_EV_vs_WT_F02.09686.09686.2 0.113 12-Jul R.IMTEFQR[166.11].Q sp|Q15464|SHB_HUMAN 1 933.4618 0.23 11532 9686 2 933.458157 467.7382 SH2 domain-containing adapter protein B OS=Homo sapiens OX=9606 GN=SHB PE=1 SV=2 6 2331.4 - 607648 - - - -3.8577 - 1.235 0.221 - 142.6 1 2 0 -0.0036 7 0 0 0 7.59E+06 3.29E+07 - - - 1.341 0.9998 221125_WJC_METTL3_EV_vs_WT_F02.09693.09693.2 0.000113 16-Jul R.SMMSPMAER.S "sp|P18583|SON_HUMAN,tr|H7C1M2|H7C1M2_HUMAN,tr|H7C1M2|H7C1M2_HUMAN" 3 1038.4297 1.28 11534 9693 2 1038.429228 520.2221 Protein SON OS=Homo sapiens OX=9606 GN=SON PE=1 SV=4 5.72 2332.4 - 1.34E+06 - - - -0.4131 - 1.692 0.465 - 213.7 1 2 0 -0.0004 9 0 0 0 5.81E+07 4.53E+07 - - - 3.9968 0.9376 221125_WJC_METTL3_EV_vs_WT_F02.09694.09694.2 0.283 14-Jun R.DLYDAGVK.R "sp|P07355|ANXA2_HUMAN,sp|A6NMY6|AXA2L_HUMAN,tr|H0YL33|H0YL33_HUMAN,tr|H0YMU9|H0YMU9_HUMAN,tr|H0YM50|H0YM50_HUMAN,tr|H0YMD0|H0YMD0_HUMAN,tr|H0YMW4|H0YMW4_HUMAN,tr|H0YN42|H0YN42_HUMAN,tr|H0YN28|H0YN28_HUMAN,tr|H0YNP5|H0YNP5_HUMAN" 10 879.4338 4.48 11535 9694 2 879.429711 440.7242 Annexin A2 OS=Homo sapiens OX=9606 GN=ANXA2 PE=1 SV=2 4.21 2332.4 - 1.68E+06 - - - -4.6473 - 1.213 0.212 - 102.7 1 2 0 -0.0041 8 0 0 0 1.99E+08 4.44E+07 - - - 1.1879 0.9993 221125_WJC_METTL3_EV_vs_WT_F02.09695.09695.2 0.00718 16-Oct K.TIAPALVSK.K "sp|P06733|ENOA_HUMAN,tr|K7ERS8|K7ERS8_HUMAN,tr|K7EM90|K7EM90_HUMAN,tr|A0A2R8Y879|A0A2R8Y879_HUMAN,tr|A0A2R8Y6I8|A0A2R8Y6I8_HUMAN,tr|A0A2R8YEM5|A0A2R8YEM5_HUMAN" 6 898.5488 1.38 11536 9695 2 898.549547 450.2817 Alpha-enolase OS=Homo sapiens OX=9606 GN=ENO1 PE=1 SV=2 8.41 2332.5 - 9.50E+06 - - - 0.867 - 1.538 0.353 - 247.9 1 2 0 0.0008 9 0 0 0 2.19E+09 1.58E+09 - - - 2.8934 0.999 221125_WJC_METTL3_EV_vs_WT_F02.09703.09703.2 0.00805 14-Aug R.TIYTSPIK[136.11].A sp|Q15477|SKIV2_HUMAN 1 929.5313 0.59 11540 9703 2 929.531715 465.7729 Helicase SKI2W OS=Homo sapiens OX=9606 GN=SKIV2L PE=1 SV=3 8.26 2333.4 - 655357 - - - 0.4099 - 1.304 0.348 - 191.7 1 2 0 0.0004 8 0 0 0 1.79E+07 3.04E+07 - - - 2.4118 0.9992 221125_WJC_METTL3_EV_vs_WT_F02.09709.09709.2 0.0864 18-Aug K.FVDGVSTVAR[166.11].F sp|O95347|SMC2_HUMAN 1 1059.5588 1.02 11542 9709 2 1059.558638 530.7867 Structural maintenance of chromosomes protein 2 OS=Homo sapiens OX=9606 GN=SMC2 PE=1 SV=2 5.84 2334.2 - 2.16E+06 - - - -0.1803 - 1.387 0.349 - 153.7 1 2 0 -0.0002 10 0 0 0 1.22E+08 1.20E+08 - - - 2.5318 0.9981 221125_WJC_METTL3_EV_vs_WT_F02.09714.09714.2 4.82 16-Aug K.TLDPDPAIR[166.11].R sp|P55060|XPO2_HUMAN 1 1006.5323 1.01 11544 9714 2 1006.532722 504.2734 Exportin-2 OS=Homo sapiens OX=9606 GN=CSE1L PE=1 SV=3 4.21 2334.8 - 904331 - - - 0.4391 - 1.582 0.204 - 200.4 1 2 0 0.0004 9 0 0 0 2.76E+08 2.74E+08 - - - 1.8746 0.9995 221125_WJC_METTL3_EV_vs_WT_F02.09715.09715.2 0.000154 18-Sep K.IVQMTEAEVR.G "sp|P62140|PP1B_HUMAN,tr|C9JP48|C9JP48_HUMAN,tr|C9J9S3|C9J9S3_HUMAN" 3 1174.6016 1.39 11545 9715 2 1174.603612 588.3081 Serine\threonine-protein phosphatase PP1-beta catalytic subunit OS=Homo sapiens OX=9606 GN=PPP1CB PE=1 SV=3 4.53 2334.9 - 248153 - - - 1.7061 - 1.879 0.414 - 196.2 1 2 0 0.002 10 0 0 0 1.04E+07 7.45E+06 - - - 3.8588 0.9943 221125_WJC_METTL3_EV_vs_WT_F02.09720.09720.2 0.0725 12-Jul K.VLGYYC[160.03]R.R sp|Q8N2G6|ZCH24_HUMAN 1 929.4429 0.8 11547 9720 2 929.44265 465.7287 Zinc finger CCHC domain-containing protein 24 OS=Homo sapiens OX=9606 GN=ZCCHC24 PE=1 SV=1 8.17 2335.7 - 569723 - - - -0.2937 - 1.043 0.249 - 148.6 1 2 0 -0.0003 7 0 0 0 2.94E+07 3.66E+07 - - - 1.0134 0.8345 221125_WJC_METTL3_EV_vs_WT_F02.09722.09722.2 0.00316 16-Sep R.VPLDVAC[160.03]AR.G "sp|Q15149|PLEC_HUMAN,tr|H0YDN1|H0YDN1_HUMAN" 2 999.5172 2.58 11548 9722 2 1000.522814 500.7659 Plectin OS=Homo sapiens OX=9606 GN=PLEC PE=1 SV=3 5.8 2335.9 - 1.67E+06 - - - 1006.1488 - 1.794 0.204 - 297.6 1 2 0 1.0057 9 0 0 0 1.42E+08 5.51E+07 - - - 1.9228 0.9974 221125_WJC_METTL3_EV_vs_WT_F02.09723.09723.2 0.164 14-Jun R.ITTMQLER.E sp|Q14152|EIF3A_HUMAN 1 990.5168 0.85 11549 9723 2 990.516188 496.2657 Eukaryotic translation initiation factor 3 subunit A OS=Homo sapiens OX=9606 GN=EIF3A PE=1 SV=1 6 2336 - 1.21E+06 - - - -0.634 - 1.383 0.217 - 101.3 1 2 0 -0.0006 8 0 0 0 1.33E+08 1.55E+08 - - - 1.6215 0.9366 221125_WJC_METTL3_EV_vs_WT_F02.09726.09726.2 1.34 14-Jul K.GITLSVRP.- tr|A0A075B6Z2|A0A075B6Z2_HUMAN 1 841.5022 692.62 11550 9726 2 841.501173 421.7584 T cell receptor alpha joining 56 (Fragment) OS=Homo sapiens OX=9606 GN=TRAJ56 PE=4 SV=1 9.75 2336.4 - 4.75E+06 - - - -1.1634 - 1.274 0.001 - 163.5 3 2 0 -0.001 8 0 0 0 1.49E+11 2.15E+08 - - - -0.4347 0.9683 221125_WJC_METTL3_EV_vs_WT_F02.09731.09731.2 0.067 14-Jun K.FFPASADR[166.11].T "sp|P07237|PDIA1_HUMAN,tr|A0A7P0TA97|A0A7P0TA97_HUMAN,tr|A0A7P0T8C0|A0A7P0T8C0_HUMAN,tr|H7BZ94|H7BZ94_HUMAN,tr|B3KTQ9|B3KTQ9_HUMAN,tr|A0A7P0TA71|A0A7P0TA71_HUMAN,tr|I3L4M2|I3L4M2_HUMAN,tr|A0A7P0T9K9|A0A7P0T9K9_HUMAN,tr|H0Y3Z3|H0Y3Z3_HUMAN,tr|A0A7P0TA35|A0A7P0TA35_HUMAN,tr|A0A7P0TB26|A0A7P0TB26_HUMAN,tr|I3L0S0|I3L0S0_HUMAN,tr|I3L3P5|I3L3P5_HUMAN,tr|A0A7P0T8J3|A0A7P0T8J3_HUMAN,tr|A0A7P0T8X1|A0A7P0T8X1_HUMAN" 15 919.4427 1.5 11554 9731 2 919.442674 460.7286 Protein disulfide-isomerase OS=Homo sapiens OX=9606 GN=P4HB PE=1 SV=3 5.84 2336.9 - 1.16E+06 - - - -0.0685 - 1.25 0.019 - 136.5 1 2 0 -0.0001 8 0 0 0 7.37E+07 4.91E+07 - - - -0.1457 0.9675 221125_WJC_METTL3_EV_vs_WT_F02.09742.09742.2 0.0593 16-Jul K.LPPTDAYYK.L sp|Q15029|U5S1_HUMAN 1 1066.5335 4.33 11559 9742 2 1066.5289 534.274 116 kDa U5 small nuclear ribonucleoprotein component OS=Homo sapiens OX=9606 GN=EFTUD2 PE=1 SV=1 5.83 2338.3 - 1.06E+06 - - - -4.3243 - 1.113 0.294 - 66.5 1 2 0 -0.0046 9 0 0 0 5.25E+07 1.21E+07 - - - 1.5208 0.8322 221125_WJC_METTL3_EV_vs_WT_F02.09747.09747.2 0.00974 14-Jun R.YPDGIISK[136.11].P sp|Q86U44|MTA70_HUMAN 1 899.4844 0.02 11561 9747 2 899.485648 450.7495 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 5.83 2339 - 6.93E+07 - - - 1.4064 - 1.209 0.292 - 88.8 1 1 0 0.0013 8 0 0 0 7.78E+08 3.74E+10 - - - 1.7697 0.9994 221125_WJC_METTL3_EV_vs_WT_F02.09748.09748.2 0.0016 16-Aug R.SLVGLGGTK.S sp|P35908|K22E_HUMAN 1 830.4862 79.16 11562 9748 2 830.484789 416.2504 "Keratin, type II cytoskeletal 2 epidermal OS=Homo sapiens OX=9606 GN=KRT2 PE=1 SV=2" 8.47 2339 - 2.88E+07 - - - -1.6605 - 1.512 0.433 - 192.6 1 2 0 -0.0014 9 0 0 0 6.92E+09 8.75E+07 - - - 3.4348 0.9983 221125_WJC_METTL3_EV_vs_WT_F02.09753.09753.2 0.08 12-Jun K.VVVYLQK.L "sp|P53634|CATC_HUMAN,tr|A0A7I2V2F3|A0A7I2V2F3_HUMAN,tr|A0A7I2V5C5|A0A7I2V5C5_HUMAN,tr|A0A7I2V5L5|A0A7I2V5L5_HUMAN,tr|A0A7I2V3A2|A0A7I2V3A2_HUMAN,tr|A0A7I2V4Z3|A0A7I2V4Z3_HUMAN,tr|A0A7I2V2Q8|A0A7I2V2Q8_HUMAN,tr|A0A7I2V5J2|A0A7I2V5J2_HUMAN,tr|A0A7I2V466|A0A7I2V466_HUMAN,tr|A0A7I2V6E3|A0A7I2V6E3_HUMAN,tr|H0YCY8|H0YCY8_HUMAN,tr|A0A7I2V3M6|A0A7I2V3M6_HUMAN,tr|A0A7I2V2V5|A0A7I2V2V5_HUMAN" 13 847.5167 0.97 11565 9753 2 847.515393 424.7656 Dipeptidyl peptidase 1 OS=Homo sapiens OX=9606 GN=CTSC PE=1 SV=2 8.56 2339.5 - 825708 - - - -1.5893 - 1.331 0.326 - 113.8 1 2 0 -0.0013 7 0 0 0 3.67E+07 3.79E+07 - - - 2.3544 0.9932 221125_WJC_METTL3_EV_vs_WT_F02.09755.09755.2 0.0144 16-Sep K.LIITEETAK[136.11].L sp|Q9NSD9|SYFB_HUMAN 1 1024.5896 0.71 11567 9755 2 1024.585653 513.3021 Phenylalanine--tRNA ligase beta subunit OS=Homo sapiens OX=9606 GN=FARSB PE=1 SV=3 4.53 2339.7 - 534624 - - - -3.8298 - 1.656 0.276 - 226.3 1 2 0 -0.0039 9 0 0 0 5.29E+07 7.43E+07 - - - 2.5376 0.9224 221125_WJC_METTL3_EV_vs_WT_F02.09760.09760.2 4.25 12-Jun K.GLLQPVK[136.11].L "sp|Q9H6R4|NOL6_HUMAN,tr|A0A0A0MRW6|A0A0A0MRW6_HUMAN" 2 761.4891 0.001 11570 9760 2 761.48829 381.7518 Nucleolar protein 6 OS=Homo sapiens OX=9606 GN=NOL6 PE=1 SV=2 8.75 2340.4 - 3.02E+06 - - - -1.0309 - 1.115 0.001 - 133.3 1 2 0 -0.0008 7 0 0 0 0.00E+00 1.18E+08 - - - -0.6069 0.9959 221125_WJC_METTL3_EV_vs_WT_F02.09762.09762.2 0.0734 14-Jun R.LVVEMGGR[166.11].C "sp|Q9NX20|RM16_HUMAN,tr|E9PI14|E9PI14_HUMAN" 2 869.4668 0.68 11572 9762 2 869.466037 435.7407 "39S ribosomal protein L16, mitochondrial OS=Homo sapiens OX=9606 GN=MRPL16 PE=1 SV=1" 6 2340.5 - 1.73E+06 - - - -0.927 - 1.21 0.235 - 82.9 1 2 0 -0.0008 8 0 0 0 2.13E+08 3.15E+08 - - - 1.3514 0.9874 221125_WJC_METTL3_EV_vs_WT_F02.09763.09763.2 0.237 12-Jul R.LGLVDTR.Q sp|Q6P4I2|WDR73_HUMAN 1 772.4443 1.81 11573 9763 2 772.442415 387.2294 WD repeat-containing protein 73 OS=Homo sapiens OX=9606 GN=WDR73 PE=1 SV=1 5.84 2340.6 - 822204 - - - -2.4442 - 1.336 0.17 - 91.8 1 2 0 -0.0019 7 0 0 0 6.39E+07 3.53E+07 - - - 1.2139 0.9993 221125_WJC_METTL3_EV_vs_WT_F02.09764.09764.2 0.00321 16-Aug K.LIITEETAK.L sp|Q9NSD9|SYFB_HUMAN 1 1016.5754 0.65 11574 9764 2 1016.573781 509.295 Phenylalanine--tRNA ligase beta subunit OS=Homo sapiens OX=9606 GN=FARSB PE=1 SV=3 4.53 2340.7 - 448741 - - - -1.57 - 1.782 0.334 - 158 1 2 0 -0.0016 9 0 0 0 4.78E+07 7.38E+07 - - - 3.1788 0.9995 221125_WJC_METTL3_EV_vs_WT_F02.09767.09767.2 0.000116 12-Sep K.YGLNMC[160.03]R.Q "sp|P62273|RS29_HUMAN,tr|A0A2R8Y6P7|A0A2R8Y6P7_HUMAN,tr|A0A2R8Y851|A0A2R8Y851_HUMAN,tr|A0A087WTT6|A0A087WTT6_HUMAN" 4 912.3946 1 11575 9767 2 912.392563 457.2046 40S ribosomal protein S29 OS=Homo sapiens OX=9606 GN=RPS29 PE=1 SV=2 8.22 2341.1 - 2.15E+06 - - - -2.2249 - 1.594 0.481 - 245.5 1 2 0 -0.002 7 0 0 0 4.93E+09 4.92E+09 - - - 4.0704 0.9996 221125_WJC_METTL3_EV_vs_WT_F02.09769.09769.2 0.0377 16-Oct R.AAVLLEQER[166.11].Q "sp|Q13435|SF3B2_HUMAN,tr|E9PPJ0|E9PPJ0_HUMAN,tr|H0YCG1|H0YCG1_HUMAN,tr|E9PJ04|E9PJ04_HUMAN,tr|E9PJT3|E9PJT3_HUMAN" 5 1037.5745 1.11 11577 9769 2 1037.574562 519.7945 Splicing factor 3B subunit 2 OS=Homo sapiens OX=9606 GN=SF3B2 PE=1 SV=2 4.53 2341.3 - 869940 - - - 0.08 - 2.069 0.295 - 561.4 1 2 0 0.0001 9 0 0 0 2.80E+08 2.51E+08 - - - 3.3233 0.989 221125_WJC_METTL3_EV_vs_WT_F02.09779.09779.2 3.63 12-Aug R.LTTEFVK.R "sp|Q13724|MOGS_HUMAN,tr|B8ZZE2|B8ZZE2_HUMAN,tr|A0A3B3IRI7|A0A3B3IRI7_HUMAN,tr|C9JDQ1|C9JDQ1_HUMAN,tr|A0A3B3ITU6|A0A3B3ITU6_HUMAN,tr|A0A3B3ITC1|A0A3B3ITC1_HUMAN" 6 836.4644 0.65 11581 9779 2 836.462493 419.2395 Mannosyl-oligosaccharide glucosidase OS=Homo sapiens OX=9606 GN=MOGS PE=1 SV=5 6 2342.5 - 1.06E+06 - - - -2.244 - 1.496 0.121 - 144.9 1 2 0 -0.0019 7 0 0 0 1.34E+08 2.05E+08 - - - 1.2104 0.9815 221125_WJC_METTL3_EV_vs_WT_F02.09789.09789.2 0.139 12-Jun R.EILTMEK.E "sp|Q8NBT2|SPC24_HUMAN,tr|K7EJH0|K7EJH0_HUMAN,tr|K7EMX1|K7EMX1_HUMAN,tr|K7EJV2|K7EJV2_HUMAN,tr|K7ESQ2|K7ESQ2_HUMAN" 5 862.447 1.3 11585 9789 2 862.44508 432.2308 Kinetochore protein Spc24 OS=Homo sapiens OX=9606 GN=SPC24 PE=1 SV=2 4.53 2343.7 - 5.58E+06 - - - -2.232 - 1.303 0.129 - 131.3 1 2 0 -0.0019 7 0 0 0 2.89E+08 2.22E+08 - - - 0.8318 0.9925 221125_WJC_METTL3_EV_vs_WT_F02.09797.09797.2 0.0821 16-Oct R.ALEEALEAK[136.11].E "sp|P35580|MYH10_HUMAN,sp|P35749|MYH11_HUMAN" 2 980.527 1.15 11589 9797 2 980.522723 491.2708 Myosin-10 OS=Homo sapiens OX=9606 GN=MYH10 PE=1 SV=3 4.25 2344.6 - 1.15E+06 - - - -4.3385 - 2.166 0.206 - 325.4 1 2 0 -0.0043 9 0 0 0 6.43E+07 5.61E+07 - - - 2.7972 0.995 221125_WJC_METTL3_EV_vs_WT_F02.09817.09817.2 0.253 16-Oct R.ALEEALEAK.E "sp|P35580|MYH10_HUMAN,sp|P35749|MYH11_HUMAN" 2 972.5128 1.11 11598 9817 2 972.509784 487.2637 Myosin-10 OS=Homo sapiens OX=9606 GN=MYH10 PE=1 SV=3 4.25 2347 - 788368 - - - -3.0776 - 1.879 0.197 - 350.6 1 2 0 -0.003 9 0 0 0 6.46E+07 5.81E+07 - - - 2.3199 0.9981 221125_WJC_METTL3_EV_vs_WT_F02.09819.09819.2 0.0468 14-Aug R.ALYEQEIR.D sp|P07196|NFL_HUMAN 1 1020.524 1.88 11599 9819 2 1020.522072 511.2693 Neurofilament light polypeptide OS=Homo sapiens OX=9606 GN=NEFL PE=1 SV=3 4.53 2347.3 - 1.37E+06 - - - -1.899 - 1.65 0.25 - 277.2 1 2 0 -0.0019 8 0 0 0 3.72E+08 1.98E+08 - - - 2.3972 0.9711 221125_WJC_METTL3_EV_vs_WT_F02.09820.09820.2 0.0174 14-Jun K.MVMETIEK.L sp|O75533|SF3B1_HUMAN 1 979.4718 1.45 11600 9820 2 979.46695 490.7432 Splicing factor 3B subunit 1 OS=Homo sapiens OX=9606 GN=SF3B1 PE=1 SV=3 4.53 2347.4 - 1.31E+06 - - - -4.9925 - 1.45 0.267 - 108.7 2 2 0 -0.0049 8 0 0 0 1.18E+08 8.16E+07 - - - 1.9977 0.9994 221125_WJC_METTL3_EV_vs_WT_F02.09825.09825.2 0.0118 14-Aug K.MVMETIEK[136.11].L sp|O75533|SF3B1_HUMAN 1 987.486 1.46 11601 9825 2 987.484755 494.7503 Splicing factor 3B subunit 1 OS=Homo sapiens OX=9606 GN=SF3B1 PE=1 SV=3 4.53 2348.1 - 2.13E+06 - - - -1.3013 - 1.559 0.39 - 214 1 2 0 -0.0013 8 0 0 0 1.18E+08 8.08E+07 - - - 3.2604 0.951 221125_WJC_METTL3_EV_vs_WT_F02.09831.09831.2 0.00772 14-Jul R.LVVEMGGR.C "sp|Q9NX20|RM16_HUMAN,tr|E9PI14|E9PI14_HUMAN" 2 859.4586 0.69 11605 9831 2 859.456274 430.7366 "39S ribosomal protein L16, mitochondrial OS=Homo sapiens OX=9606 GN=MRPL16 PE=1 SV=1" 6 2348.6 - 4.79E+06 - - - -2.6749 - 1.49 0.036 - 169.1 2 2 0 -0.0023 8 0 0 0 2.06E+08 2.99E+08 - - - 0.3744 0.9943 221125_WJC_METTL3_EV_vs_WT_F02.09834.09834.2 0.0324 14-Jul R.VALNTLAR.C sp|Q15274|NADC_HUMAN 1 856.5131 1.61 11606 9834 2 856.511049 429.2638 Nicotinate-nucleotide pyrophosphorylase [carboxylating] OS=Homo sapiens OX=9606 GN=QPRT PE=1 SV=3 9.72 2349 - 3.78E+06 - - - -2.3374 - 1.515 0.198 - 151.1 1 2 0 -0.002 8 0 0 0 1.56E+08 9.68E+07 - - - 1.7557 0.9849 221125_WJC_METTL3_EV_vs_WT_F02.09839.09839.2 1.11 12-Jul R.DPELGLK[136.11].S sp|P49411|EFTU_HUMAN 1 778.4316 1.42 11609 9839 2 778.429905 390.2231 "Elongation factor Tu, mitochondrial OS=Homo sapiens OX=9606 GN=TUFM PE=1 SV=2" 4.37 2349.5 - 2.73E+06 - - - -2.2031 - 1.462 0.097 - 197.6 1 2 0 -0.0017 7 0 0 0 3.47E+08 2.44E+08 - - - 0.9603 0.9732 221125_WJC_METTL3_EV_vs_WT_F02.09841.09841.2 1.28 12-Jun R.IILPPEK[136.11].E sp|P49411|EFTU_HUMAN 1 816.52 1.69 11611 9841 2 816.519979 409.2673 "Elongation factor Tu, mitochondrial OS=Homo sapiens OX=9606 GN=TUFM PE=1 SV=2" 6 2349.7 - 837287 - - - -0.0759 - 1.121 0.076 - 112.8 1 2 0 -0.0001 7 0 0 0 8.02E+07 4.76E+07 - - - -0.0358 0.9995 221125_WJC_METTL3_EV_vs_WT_F02.09846.09846.2 0.126 18-Oct R.IAEVDASVVR.E sp|P31930|QCR1_HUMAN 1 1057.5768 1.26 11614 9846 2 1057.575617 529.7957 "Cytochrome b-c1 complex subunit 1, mitochondrial OS=Homo sapiens OX=9606 GN=UQCRC1 PE=1 SV=3" 4.37 2350.4 - 636440 - - - -1.094 - 1.865 0.33 - 293.6 1 2 0 -0.0012 10 0 0 0 1.36E+08 1.08E+08 - - - 3.2177 0.9613 221125_WJC_METTL3_EV_vs_WT_F02.09849.09849.2 0.00453 13/18 R.IAEVDASVVR[166.11].E sp|P31930|QCR1_HUMAN 1 1067.585 1.26 11615 9849 2 1067.578699 534.7998 "Cytochrome b-c1 complex subunit 1, mitochondrial OS=Homo sapiens OX=9606 GN=UQCRC1 PE=1 SV=3" 4.37 2350.8 - 1.12E+06 - - - -5.9433 - 2.179 0.148 - 587 1 2 0 -0.0063 10 0 0 0 1.36E+08 1.08E+08 - - - 2.3062 0.9914 221125_WJC_METTL3_EV_vs_WT_F02.09855.09855.2 0.883 14-Sep R.ALYEQEIR[166.11].D sp|P07196|NFL_HUMAN 1 1030.5323 1.88 11618 9855 2 1030.529755 516.2734 Neurofilament light polypeptide OS=Homo sapiens OX=9606 GN=NEFL PE=1 SV=3 4.53 2351.5 - 5.37E+06 - - - -2.4502 - 1.505 0.167 - 437 1 2 0 -0.0025 8 0 0 0 3.72E+08 1.98E+08 - - - 1.5066 0.981 221125_WJC_METTL3_EV_vs_WT_F02.09861.09861.2 0.117 12-Jul R.IPVQLQR.S "sp|Q8TAV4|STML3_HUMAN,sp|P27105|STOM_HUMAN" 2 852.5181 1.55 11622 9861 2 852.516389 427.2663 Stomatin-like protein 3 OS=Homo sapiens OX=9606 GN=STOML3 PE=1 SV=1 9.75 2352.2 - 2.94E+06 - - - -2.0504 - 1.586 0.03 - 157.3 1 2 0 -0.0017 7 0 0 0 1.33E+08 8.56E+07 - - - 0.7234 0.985 221125_WJC_METTL3_EV_vs_WT_F02.09865.09865.2 0.0929 20-Aug K.IIEEAPAPGIK[136.11].S "sp|Q96RQ3|MCCA_HUMAN,tr|G5E9X5|G5E9X5_HUMAN,tr|E9PG35|E9PG35_HUMAN,tr|E9PHF7|E9PHF7_HUMAN,tr|F5GYT8|F5GYT8_HUMAN" 5 1144.6583 2.64 11624 9865 2 1144.659909 573.3364 "Methylcrotonoyl-CoA carboxylase subunit alpha, mitochondrial OS=Homo sapiens OX=9606 GN=MCCC1 PE=1 SV=3" 4.53 2352.7 - 619990 - - - 1.3838 - 1.255 0.173 - 88.5 4 2 0 0.0016 11 0 0 0 2.54E+07 9.61E+06 - - - 0.6638 0.8015 221125_WJC_METTL3_EV_vs_WT_F02.09871.09871.2 0.203 12-Jul L.LENQLLR.E "sp|P17861|XBP1_HUMAN,sp|Q96JB1|DYH8_HUMAN,sp|Q8TBA6|GOGA5_HUMAN,tr|B1AHH2|B1AHH2_HUMAN,tr|A0A075B6F3|A0A075B6F3_HUMAN,tr|B1AHH1|B1AHH1_HUMAN,tr|H0Y7V4|H0Y7V4_HUMAN" 7 884.508 2.03 11626 9871 2 884.507548 443.2613 X-box-binding protein 1 OS=Homo sapiens OX=9606 GN=XBP1 PE=1 SV=2 6 2353.5 - 838426 - - - -0.4726 - 1.488 0.13 - 157.6 1 1 0 -0.0004 7 0 0 0 1.74E+08 8.59E+07 - - - 1.2603 0.999 221125_WJC_METTL3_EV_vs_WT_F02.09873.09873.2 0.0137 14-Jul R.LVVGDSLK.A sp|P48634|PRC2A_HUMAN 1 829.4909 2.3 11627 9873 2 829.489994 415.7527 Protein PRRC2A OS=Homo sapiens OX=9606 GN=PRRC2A PE=1 SV=3 5.84 2353.7 - 6.86E+06 - - - -1.1151 - 1.427 0.334 - 144.4 1 2 0 -0.0009 8 0 0 0 3.81E+08 1.66E+08 - - - 2.58 0.9971 221125_WJC_METTL3_EV_vs_WT_F02.09878.09878.2 0.00609 12-Jul R.AQFLVEK.A "sp|Q99623|PHB2_HUMAN,tr|F5H3X6|F5H3X6_HUMAN,tr|F5GWA7|F5GWA7_HUMAN,tr|F5GY37|F5GY37_HUMAN" 4 833.4647 415.78 11629 9878 2 833.464577 417.7396 Prohibitin-2 OS=Homo sapiens OX=9606 GN=PHB2 PE=1 SV=2 6.05 2354.3 - 8.22E+06 - - - -0.1524 - 1.524 0.151 - 307.7 1 2 0 -0.0001 7 0 0 0 6.37E+08 1.53E+06 - - - 1.4913 0.9984 221125_WJC_METTL3_EV_vs_WT_F02.09886.09886.2 0.000118 14-Oct K.YLQQAFEK.S sp|Q9Y2X9|ZN281_HUMAN 1 1025.5182 0.95 11631 9886 2 1025.514344 513.7664 Zinc finger protein 281 OS=Homo sapiens OX=9606 GN=ZNF281 PE=1 SV=1 6 2355.6 - 541797 - - - -3.7561 - 1.808 0.435 - 260.9 1 2 0 -0.0039 8 0 0 0 3.14E+07 3.30E+07 - - - 4.0388 0.9713 221125_WJC_METTL3_EV_vs_WT_F02.09888.09888.2 1.97 14-Jun R.LPPPPDIK.K "sp|P51114|FXR1_HUMAN,tr|C9JAJ4|C9JAJ4_HUMAN,tr|B4DXZ6|B4DXZ6_HUMAN" 3 875.5117 1.53 11632 9888 2 875.510979 438.7631 Fragile X mental retardation syndrome-related protein 1 OS=Homo sapiens OX=9606 GN=FXR1 PE=1 SV=3 5.84 2355.8 - 1.19E+06 - - - -0.771 - 1.246 0.089 - 89.4 7 2 0 -0.0007 8 0 0 0 5.00E+08 3.28E+08 - - - -0.016 0.9986 221125_WJC_METTL3_EV_vs_WT_F02.09908.09908.2 0.00103 12-Jul K.YGLNMC[160.03]R[166.11].Q "sp|P62273|RS29_HUMAN,tr|A0A2R8Y6P7|A0A2R8Y6P7_HUMAN,tr|A0A2R8Y851|A0A2R8Y851_HUMAN,tr|A0A087WTT6|A0A087WTT6_HUMAN" 4 922.4029 1 11641 9908 2 922.400423 462.2087 40S ribosomal protein S29 OS=Homo sapiens OX=9606 GN=RPS29 PE=1 SV=2 8.22 2358.1 - 904991 - - - -2.6453 - 1.561 0.381 - 187.9 1 2 0 -0.0024 7 0 0 0 4.93E+09 4.92E+09 - - - 3.2653 0.9963 221125_WJC_METTL3_EV_vs_WT_F02.09914.09914.2 0.641 16-Jul R.MVEGYQGLR.C "sp|Q15149|PLEC_HUMAN,tr|E9PMV1|E9PMV1_HUMAN,tr|E9PKG0|E9PKG0_HUMAN,tr|H0YDN1|H0YDN1_HUMAN" 4 1051.5121 3.98 11645 9914 2 1051.513029 526.7633 Plectin OS=Homo sapiens OX=9606 GN=PLEC PE=1 SV=3 5.75 2358.9 - 435607 - - - 0.9168 - 1.298 0.232 - 132.4 1 2 0 0.001 9 0 0 0 1.93E+07 4.84E+06 - - - 1.5088 0.9791 221125_WJC_METTL3_EV_vs_WT_F02.09916.09916.2 0.0034 16-Sep K.LVEALC[160.03]AEH.Q sp|P25398|RS12_HUMAN 1 1040.4961 - 11647 9916 2 1040.49406 521.2553 40S ribosomal protein S12 OS=Homo sapiens OX=9606 GN=RPS12 PE=1 SV=3 4.51 2359 - 327684 - - - -1.9423 - 1.721 0.499 - 265.5 1 1 0 -0.002 9 0 0 0 - - - - - 4.2966 0.9972 221125_WJC_METTL3_EV_vs_WT_F02.09924.09924.2 0.197 16-Sep R.GAVIATELK[136.11].N sp|O15371|EIF3D_HUMAN 1 908.5422 0.93 11650 9924 2 908.540464 455.2784 Eukaryotic translation initiation factor 3 subunit D OS=Homo sapiens OX=9606 GN=EIF3D PE=1 SV=1 6 2360.1 - 4.66E+06 - - - -1.9471 - 1.723 0.203 - 230 1 2 0 -0.0018 9 0 0 0 5.14E+08 5.54E+08 - - - 2.1138 0.9864 221125_WJC_METTL3_EV_vs_WT_F02.09930.09930.2 0.269 16-Aug R.GAVIATELK.N sp|O15371|EIF3D_HUMAN 1 900.528 0.99 11653 9930 2 900.526862 451.2713 Eukaryotic translation initiation factor 3 subunit D OS=Homo sapiens OX=9606 GN=EIF3D PE=1 SV=1 6 2360.8 - 5.75E+06 - - - -1.3003 - 1.459 0.067 - 194.5 1 2 0 -0.0012 9 0 0 0 5.14E+08 5.18E+08 - - - 0.6283 0.9977 221125_WJC_METTL3_EV_vs_WT_F02.09936.09936.2 0.671 16-Jul R.VLDPTC[160.03]TIK.T "sp|Q8TED0|UTP15_HUMAN,tr|H0Y8P4|H0Y8P4_HUMAN" 2 1045.5478 1.2 11656 9936 2 1045.546539 523.7812 U3 small nucleolar RNA-associated protein 15 homolog OS=Homo sapiens OX=9606 GN=UTP15 PE=1 SV=3 5.8 2361.4 - 326968 - - - -1.1889 - 1.496 0.228 - 128.2 1 2 0 -0.0012 9 0 0 0 1.73E+07 1.44E+07 - - - 1.8899 0.9946 221125_WJC_METTL3_EV_vs_WT_F02.09938.09938.2 0.212 12-May K.VVQYLVK[136.11].E "sp|Q8IWZ3|ANKH1_HUMAN,tr|E9PDP5|E9PDP5_HUMAN,tr|H3BLS9|H3BLS9_HUMAN,tr|H0Y4P6|H0Y4P6_HUMAN,tr|H7C2F5|H7C2F5_HUMAN" 5 855.5309 2.89 11658 9938 2 855.528677 428.7727 Ankyrin repeat and KH domain-containing protein 1 OS=Homo sapiens OX=9606 GN=ANKHD1 PE=1 SV=1 8.56 2361.6 - 4.22E+06 - - - -2.6451 - 1.282 0.293 - 65.9 1 2 0 -0.0023 7 0 0 0 1.16E+09 4.00E+08 - - - 1.9915 0.9874 221125_WJC_METTL3_EV_vs_WT_F02.09943.09943.2 1.61 12-Jul R.LGPETFR.Q sp|P57086|SCND1_HUMAN 1 818.4287 1.66 11661 9943 2 818.430231 410.2216 SCAN domain-containing protein 1 OS=Homo sapiens OX=9606 GN=SCAND1 PE=1 SV=1 6 2362.2 - 1.60E+06 - - - 1.9281 - 1.45 0.107 - 132.4 1 2 0 0.0016 7 0 0 0 4.70E+08 2.83E+08 - - - 1.0081 0.9994 221125_WJC_METTL3_EV_vs_WT_F02.09948.09948.2 0.00975 14-Sep R.MLEAQLER[166.11].R sp|Q9Y6D9|MD1L1_HUMAN 1 998.5094 3.88 11664 9948 2 998.508244 500.262 Mitotic spindle assembly checkpoint protein MAD1 OS=Homo sapiens OX=9606 GN=MAD1L1 PE=1 SV=2 4.53 2362.8 - 1.84E+06 - - - -1.1938 - 1.896 0.284 - 320.5 1 2 0 -0.0012 8 0 0 0 4.49E+08 1.16E+08 - - - 3.0677 0.996 221125_WJC_METTL3_EV_vs_WT_F02.09954.09954.2 0.00995 14-Jun R.LPPPPDIK.K "sp|P51114|FXR1_HUMAN,tr|C9JAJ4|C9JAJ4_HUMAN,tr|B4DXZ6|B4DXZ6_HUMAN" 3 875.5117 1.55 11666 9954 2 875.510188 438.7631 Fragile X mental retardation syndrome-related protein 1 OS=Homo sapiens OX=9606 GN=FXR1 PE=1 SV=3 5.84 2363.6 - 4.37E+06 - - - -1.6744 - 1.279 0.256 - 94.4 1 2 0 -0.0015 8 0 0 0 4.98E+08 3.22E+08 - - - 1.6735 0.8722 221125_WJC_METTL3_EV_vs_WT_F02.09970.09970.2 4.07 12-May R.QPVLAIK.G "sp|P27694|RFA1_HUMAN,tr|I3L4R8|I3L4R8_HUMAN" 2 767.4905 1.24 11671 9970 2 767.488811 384.7525 Replication protein A 70 kDa DNA-binding subunit OS=Homo sapiens OX=9606 GN=RPA1 PE=1 SV=2 8.75 2365.9 - 1.28E+07 - - - -2.2333 - 1.091 0.026 - 146.3 1 2 0 -0.0017 7 0 0 0 9.49E+08 7.67E+08 - - - -0.4915 0.997 221125_WJC_METTL3_EV_vs_WT_F02.09973.09973.2 0.279 14-Jul R.LADPEVLK[136.11].R sp|O95628|CNOT4_HUMAN 1 891.5157 2.01 11672 9973 2 891.515687 446.7651 CCR4-NOT transcription complex subunit 4 OS=Homo sapiens OX=9606 GN=CNOT4 PE=1 SV=3 4.37 2366.3 - 1.52E+06 - - - 0.0034 - 1.424 0.184 - 115.3 1 2 0 0 8 0 0 0 2.88E+08 1.43E+08 - - - 1.4661 0.9671 221125_WJC_METTL3_EV_vs_WT_F02.09975.09975.2 0.996 14-Jul K.GITLSVRP.- tr|A0A075B6Z2|A0A075B6Z2_HUMAN 1 841.5022 766.83 11673 9975 2 841.501846 421.7584 T cell receptor alpha joining 56 (Fragment) OS=Homo sapiens OX=9606 GN=TRAJ56 PE=4 SV=1 9.75 2366.5 - 1.26E+09 - - - -0.3636 - 1.307 0.017 - 190.5 2 2 0 -0.0003 8 0 0 0 1.49E+11 1.94E+08 - - - -0.1605 0.9947 221125_WJC_METTL3_EV_vs_WT_F02.09977.09977.2 0.857 14-Sep R.LADPEVLK.R sp|O95628|CNOT4_HUMAN 1 883.5015 2.02 11674 9977 2 883.499093 442.758 CCR4-NOT transcription complex subunit 4 OS=Homo sapiens OX=9606 GN=CNOT4 PE=1 SV=3 4.37 2366.7 - 2.35E+06 - - - -2.7063 - 1.479 0.247 - 199.8 1 2 0 -0.0024 8 0 0 0 2.88E+08 1.43E+08 - - - 2.0449 0.9945 221125_WJC_METTL3_EV_vs_WT_F02.09978.09978.2 2.51 12-Sep K.TLEVLTK[136.11].N "sp|Q5T8P6|RBM26_HUMAN,sp|Q8NFQ6|BPIFC_HUMAN,tr|A0A087X0H9|A0A087X0H9_HUMAN" 3 810.4942 0.93 11675 9978 2 810.493024 406.2544 RNA-binding protein 26 OS=Homo sapiens OX=9606 GN=RBM26 PE=1 SV=3 5.66 2366.8 - 1.61E+06 - - - -1.4756 - 1.505 0.137 - 212.5 1 2 0 -0.0012 7 0 0 0 1.33E+08 1.43E+08 - - - 1.3478 0.9856 221125_WJC_METTL3_EV_vs_WT_F02.09981.09981.2 0.0692 16-Sep K.TPLLGDGPR[166.11].A sp|Q9C0J8|WDR33_HUMAN 1 934.5112 0.67 11676 9981 2 934.514333 468.2629 pre-mRNA 3' end processing protein WDR33 OS=Homo sapiens OX=9606 GN=WDR33 PE=1 SV=2 5.5 2367.2 - 528872 - - - 3.405 - 1.664 0.155 - 220.3 1 2 0 0.0032 9 0 0 0 1.06E+08 1.57E+08 - - - 1.658 0.9989 221125_WJC_METTL3_EV_vs_WT_F02.09990.09990.2 0.0312 14-Aug K.ALVAYYQK[136.11].Y "sp|P62249|RS16_HUMAN,tr|M0R210|M0R210_HUMAN,tr|M0R3H0|M0R3H0_HUMAN,tr|M0QX76|M0QX76_HUMAN,tr|M0R1M5|M0R1M5_HUMAN" 5 962.5317 0.81 11680 9990 2 962.529545 482.2731 40S ribosomal protein S16 OS=Homo sapiens OX=9606 GN=RPS16 PE=1 SV=2 8.54 2368.3 - 2.93E+07 - - - -2.2056 - 1.714 0.336 - 267.7 1 2 0 -0.0021 8 0 0 0 2.49E+09 3.08E+09 - - - 3.1471 0.9994 221125_WJC_METTL3_EV_vs_WT_F02.09991.09991.2 0.00367 14-Aug R.IGC[160.03]IITAR.K "sp|Q12904|AIMP1_HUMAN,tr|A0A804HJ47|A0A804HJ47_HUMAN,tr|A0A5F9ZHC5|A0A5F9ZHC5_HUMAN" 3 902.5008 0.83 11681 9991 2 902.499305 452.2577 Aminoacyl tRNA synthase complex-interacting multifunctional protein 1 OS=Homo sapiens OX=9606 GN=AIMP1 PE=1 SV=2 8.25 2368.3 - 7.11E+06 - - - -1.6255 - 1.982 0.296 - 224.1 1 2 0 -0.0015 8 0 0 0 3.20E+08 3.87E+08 - - - 3.29 0.9994 221125_WJC_METTL3_EV_vs_WT_F02.09992.09992.2 0.00114 14-Aug R.IGC[160.03]IITAR[166.11].K "sp|Q12904|AIMP1_HUMAN,tr|A0A804HJ47|A0A804HJ47_HUMAN,tr|A0A5F9ZHC5|A0A5F9ZHC5_HUMAN" 3 912.509 0.83 11682 9992 2 912.50773 457.2618 Aminoacyl tRNA synthase complex-interacting multifunctional protein 1 OS=Homo sapiens OX=9606 GN=AIMP1 PE=1 SV=2 8.25 2368.4 - 6.49E+06 - - - -1.4378 - 1.813 0.334 - 217.5 1 2 0 -0.0013 8 0 0 0 3.19E+08 3.85E+08 - - - 3.302 0.9981 221125_WJC_METTL3_EV_vs_WT_F02.09995.09995.2 0.000178 16-Sep K.LPPTDAYYK.L sp|Q15029|U5S1_HUMAN 1 1066.5335 0.81 11683 9995 2 1066.529228 534.274 116 kDa U5 small nuclear ribonucleoprotein component OS=Homo sapiens OX=9606 GN=EFTUD2 PE=1 SV=1 5.83 2368.8 - 916412 - - - -4.0168 - 1.812 0.448 - 364.4 1 2 0 -0.0043 9 0 0 0 5.32E+07 6.54E+07 - - - 4.0683 0.8661 221125_WJC_METTL3_EV_vs_WT_F02.10000.10000.2 0.349 12-Aug N.LNTLIQR[166.11].S "sp|P20036|DPA1_HUMAN,sp|Q00839|HNRPU_HUMAN,sp|Q8IUG5|MY18B_HUMAN,tr|A0A140T914|A0A140T914_HUMAN,tr|A0A1W2PQL0|A0A1W2PQL0_HUMAN,tr|A0A1W2PPE9|A0A1W2PPE9_HUMAN,tr|A0A1W2PPL4|A0A1W2PPL4_HUMAN,tr|A0A1W2PQ74|A0A1W2PQ74_HUMAN,tr|F5H6I8|F5H6I8_HUMAN,tr|A0A140T9R4|A0A140T9R4_HUMAN,tr|Q5RI18|Q5RI18_HUMAN,tr|A0A140T9D6|A0A140T9D6_HUMAN,tr|A0A1W2PP35|A0A1W2PP35_HUMAN,tr|A0A1W2PPS1|A0A1W2PPS1_HUMAN,tr|A0A140T9Y9|A0A140T9Y9_HUMAN,tr|A0A1W2PRZ7|A0A1W2PRZ7_HUMAN,tr|A0A140T9H1|A0A140T9H1_HUMAN,tr|A0A1W2PPH7|A0A1W2PPH7_HUMAN,tr|A0A1W2PQD4|A0A1W2PQD4_HUMAN,tr|A0A140T9U4|A0A140T9U4_HUMAN,tr|A0A1W2PP34|A0A1W2PP34_HUMAN,tr|A0A1X7SBS1|A0A1X7SBS1_HUMAN,tr|A0A140T9F8|A0A140T9F8_HUMAN,tr|J3KQ99|J3KQ99_HUMAN" 24 866.5213 1.06 11684 10000 2 866.51984 434.2679 "HLA class II histocompatibility antigen, DP alpha 1 chain OS=Homo sapiens OX=9606 GN=HLA-DPA1 PE=1 SV=1" 9.75 2369.5 - 3.43E+06 - - - -1.7091 - 1.911 0.13 - 206.6 1 1 0 -0.0015 7 0 0 0 1.85E+10 1.74E+10 - - - 2.0528 0.9987 221125_WJC_METTL3_EV_vs_WT_F02.10002.10002.2 0.0159 14-Aug K.ALVAYYQK.Y "sp|P62249|RS16_HUMAN,tr|M0R210|M0R210_HUMAN,tr|M0R3H0|M0R3H0_HUMAN,tr|M0QX76|M0QX76_HUMAN,tr|M0R1M5|M0R1M5_HUMAN" 5 954.5175 0.81 11685 10002 2 954.516142 478.266 40S ribosomal protein S16 OS=Homo sapiens OX=9606 GN=RPS16 PE=1 SV=2 8.54 2369.7 - 3.39E+07 - - - -1.3892 - 1.6 0.277 - 252 1 2 0 -0.0013 8 0 0 0 2.50E+09 3.08E+09 - - - 2.504 0.9901 221125_WJC_METTL3_EV_vs_WT_F02.10003.10003.2 0.166 14-Jul R.APIIAVTR[166.11].N "sp|P14618|KPYM_HUMAN,tr|B4DNK4|B4DNK4_HUMAN,tr|A0A804F6T5|A0A804F6T5_HUMAN,tr|H3BTN5|H3BTN5_HUMAN,tr|H3BR70|H3BR70_HUMAN,tr|A0A804F729|A0A804F729_HUMAN" 6 849.5312 1.29 11686 10003 2 849.527708 425.7729 Pyruvate kinase PKM OS=Homo sapiens OX=9606 GN=PKM PE=1 SV=4 9.79 2369.7 - 1.58E+07 - - - -4.0611 - 1.647 0.244 - 258.6 1 2 0 -0.0034 8 0 0 0 9.93E+08 7.69E+08 - - - 2.3469 0.9945 221125_WJC_METTL3_EV_vs_WT_F02.10019.10019.2 0.407 12-Jul R.WADLEEK.K "sp|P49750|YLPM1_HUMAN,tr|F8VU51|F8VU51_HUMAN" 2 889.4181 2.41 11692 10019 2 889.415747 445.7164 YLP motif-containing protein 1 OS=Homo sapiens OX=9606 GN=YLPM1 PE=1 SV=4 4.14 2371.8 - 1.14E+06 - - - -2.6995 - 1.303 0.287 - 108 1 2 0 -0.0024 7 0 0 0 4.97E+07 2.06E+07 - - - 1.9986 0.906 221125_WJC_METTL3_EV_vs_WT_F02.10027.10027.2 0.103 12-Aug K.NASILLK.E "sp|Q8IWZ3|ANKH1_HUMAN,tr|E9PDP5|E9PDP5_HUMAN,tr|H3BLS9|H3BLS9_HUMAN,tr|H0Y4P6|H0Y4P6_HUMAN,tr|H7C2F5|H7C2F5_HUMAN" 5 757.4698 0.05 11695 10027 2 758.473227 379.7422 Ankyrin repeat and KH domain-containing protein 1 OS=Homo sapiens OX=9606 GN=ANKHD1 PE=1 SV=1 8.75 2372.9 - 1.17E+06 - - - 1324.7221 - 1.633 0.181 - 263.8 1 2 0 1.0034 7 0 0 0 3.65E+07 7.72E+08 - - - 1.6167 0.9995 221125_WJC_METTL3_EV_vs_WT_F02.10037.10037.2 0.00299 16-Sep K.LDGGIEPYR.L "sp|Q9UKL0|RCOR1_HUMAN,tr|H0YNY4|H0YNY4_HUMAN" 2 1018.5084 2.45 11698 10037 2 1018.509279 510.2615 REST corepressor 1 OS=Homo sapiens OX=9606 GN=RCOR1 PE=1 SV=2 4.37 2374.2 - 772965 - - - 0.9023 - 1.732 0.356 - 154.3 1 2 0 0.0009 9 0 0 0 3.04E+07 1.24E+07 - - - 3.2592 0.9777 221125_WJC_METTL3_EV_vs_WT_F02.10042.10042.2 0.198 16-May K.VVPDPNVIK.L "sp|Q9NUU7|DD19A_HUMAN,sp|Q9UMR2|DD19B_HUMAN,tr|F6QDS0|F6QDS0_HUMAN,tr|I3L352|I3L352_HUMAN,tr|H3BQK0|H3BQK0_HUMAN,tr|I3L0H8|I3L0H8_HUMAN" 6 979.5702 1.17 11700 10042 2 979.571154 490.7924 ATP-dependent RNA helicase DDX19A OS=Homo sapiens OX=9606 GN=DDX19A PE=1 SV=1 5.81 2374.9 - 0 - - - 0.9412 - 1.09 0.13 - 70.2 1 2 0 0.0009 9 0 0 0 6.47E+07 5.51E+07 - - - 0.2502 0.9235 221125_WJC_METTL3_EV_vs_WT_F02.10043.10043.2 1.23 12-Jul K.ELSFGAR[166.11].A "sp|P11172|UMPS_HUMAN,tr|E9PFD2|E9PFD2_HUMAN" 2 788.4056 0.82 11701 10043 2 788.402045 395.2101 Uridine 5'-monophosphate synthase OS=Homo sapiens OX=9606 GN=UMPS PE=1 SV=1 6.1 2375.1 - 1.12E+06 - - - -4.5383 - 1.352 0.133 - 197.3 1 2 0 -0.0036 7 0 0 0 7.42E+07 9.09E+07 - - - 0.9778 0.7816 221125_WJC_METTL3_EV_vs_WT_F02.10047.10047.2 0.13 14-Aug V.VGPVSLPR.R "sp|Q12802|AKP13_HUMAN,tr|A0A087WTD7|A0A087WTD7_HUMAN,tr|A8MYJ1|A8MYJ1_HUMAN" 3 823.4916 25.61 11702 10047 2 823.490369 412.7531 A-kinase anchor protein 13 OS=Homo sapiens OX=9606 GN=AKAP13 PE=1 SV=2 9.72 2375.6 - 3.50E+07 - - - -1.4803 - 1.499 0.164 - 236.1 1 1 0 -0.0012 8 0 0 0 4.32E+09 1.69E+08 - - - 1.4728 0.9968 221125_WJC_METTL3_EV_vs_WT_F02.10048.10048.2 0.0804 12-Aug K.NASILLK[136.11].E "sp|Q8IWZ3|ANKH1_HUMAN,tr|E9PDP5|E9PDP5_HUMAN,tr|H3BLS9|H3BLS9_HUMAN,tr|H0Y4P6|H0Y4P6_HUMAN,tr|H7C2F5|H7C2F5_HUMAN" 5 765.484 0.06 11703 10048 2 765.482535 383.7493 Ankyrin repeat and KH domain-containing protein 1 OS=Homo sapiens OX=9606 GN=ANKHD1 PE=1 SV=1 8.75 2375.7 - 8.84E+06 - - - -1.9008 - 1.628 0.189 - 344.3 1 2 0 -0.0015 7 0 0 0 3.53E+07 6.34E+08 - - - 1.9807 0.9948 221125_WJC_METTL3_EV_vs_WT_F02.10052.10052.2 0.0395 16-Jul K.VVPDPNVIK[136.11].L "sp|Q9NUU7|DD19A_HUMAN,sp|Q9UMR2|DD19B_HUMAN,tr|F6QDS0|F6QDS0_HUMAN,tr|I3L352|I3L352_HUMAN,tr|H3BQK0|H3BQK0_HUMAN,tr|I3L0H8|I3L0H8_HUMAN" 6 987.5844 1.17 11705 10052 2 987.58251 494.7995 ATP-dependent RNA helicase DDX19A OS=Homo sapiens OX=9606 GN=DDX19A PE=1 SV=1 5.81 2376.2 - 726129 - - - -1.9462 - 1.246 0.262 - 155.1 1 2 0 -0.0019 9 0 0 0 6.47E+07 5.51E+07 - - - 1.6118 0.9952 221125_WJC_METTL3_EV_vs_WT_F02.10053.10053.2 0.116 14-Jul K.IILPEGAK[136.11].N "sp|P04843|RPN1_HUMAN,tr|B7Z4L4|B7Z4L4_HUMAN" 2 847.5259 0.56 11706 10053 2 847.523678 424.7702 Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit 1 OS=Homo sapiens OX=9606 GN=RPN1 PE=1 SV=1 6 2376.2 - 1.16E+07 - - - -2.5675 - 1.195 0.333 - 121.8 1 2 0 -0.0022 8 0 0 0 6.50E+08 1.17E+09 - - - 2.0371 0.9591 221125_WJC_METTL3_EV_vs_WT_F02.10065.10065.2 0.232 14-Jul R.GAIPSYMK[136.11].A sp|Q15208|STK38_HUMAN 1 873.451 2.69 11709 10065 2 873.447825 437.7328 Serine\threonine-protein kinase 38 OS=Homo sapiens OX=9606 GN=STK38 PE=1 SV=1 8.59 2377.9 - 1.97E+06 - - - -3.6064 - 1.27 0.163 - 80.2 1 2 0 -0.0032 8 0 0 0 2.74E+08 1.02E+08 - - - 0.9648 0.991 221125_WJC_METTL3_EV_vs_WT_F02.10066.10066.2 0.236 16-Aug R.TVPLYESPR.K "sp|Q16531|DDB1_HUMAN,tr|A0A7P0TAK7|A0A7P0TAK7_HUMAN,tr|A0A7P0T870|A0A7P0T870_HUMAN,tr|A0A7P0TB30|A0A7P0TB30_HUMAN,tr|A0A7P0Z3Z5|A0A7P0Z3Z5_HUMAN,tr|F5GY55|F5GY55_HUMAN,tr|A0A7P0Z4B9|A0A7P0Z4B9_HUMAN,tr|A0A7P0T965|A0A7P0T965_HUMAN" 8 1060.5553 2.05 11710 10066 2 1060.557262 531.2849 DNA damage-binding protein 1 OS=Homo sapiens OX=9606 GN=DDB1 PE=1 SV=1 5.66 2378 - 781537 - - - 1.8405 - 1.316 0.186 - 93.8 1 2 0 0.002 9 0 0 0 2.62E+07 1.28E+07 - - - 1.2086 0.993 221125_WJC_METTL3_EV_vs_WT_F02.10067.10067.2 0.841 12-Jun K.ELSFGAR.A "sp|P11172|UMPS_HUMAN,tr|E9PFD2|E9PFD2_HUMAN" 2 778.3974 0.8 11711 10067 2 778.39631 390.206 Uridine 5'-monophosphate synthase OS=Homo sapiens OX=9606 GN=UMPS PE=1 SV=1 6.1 2378.1 - 1.87E+06 - - - -1.3399 - 1.328 0.158 - 221 1 2 0 -0.001 7 0 0 0 7.42E+07 9.26E+07 - - - 1.1065 0.9483 221125_WJC_METTL3_EV_vs_WT_F02.10070.10070.2 4.98 14-Aug K.IVDVIGEK.L "sp|P13861|KAP2_HUMAN,tr|H7C4A9|H7C4A9_HUMAN" 2 871.5015 1.78 11712 10070 2 871.498119 436.758 cAMP-dependent protein kinase type II-alpha regulatory subunit OS=Homo sapiens OX=9606 GN=PRKAR2A PE=1 SV=2 4.37 2378.5 - 1.18E+07 - - - -3.8612 - 1.375 0.125 - 99.2 1 2 0 -0.0034 8 0 0 0 6.08E+08 3.41E+08 - - - 0.9236 0.8135 221125_WJC_METTL3_EV_vs_WT_F02.10075.10075.2 0.238 12-Aug N.LNTLIQR.S "sp|P20036|DPA1_HUMAN,sp|Q00839|HNRPU_HUMAN,sp|Q8IUG5|MY18B_HUMAN,tr|A0A140T914|A0A140T914_HUMAN,tr|A0A1W2PQL0|A0A1W2PQL0_HUMAN,tr|A0A1W2PPE9|A0A1W2PPE9_HUMAN,tr|A0A1W2PPL4|A0A1W2PPL4_HUMAN,tr|A0A1W2PQ74|A0A1W2PQ74_HUMAN,tr|F5H6I8|F5H6I8_HUMAN,tr|A0A140T9R4|A0A140T9R4_HUMAN,tr|Q5RI18|Q5RI18_HUMAN,tr|A0A140T9D6|A0A140T9D6_HUMAN,tr|A0A1W2PP35|A0A1W2PP35_HUMAN,tr|A0A1W2PPS1|A0A1W2PPS1_HUMAN,tr|A0A140T9Y9|A0A140T9Y9_HUMAN,tr|A0A1W2PRZ7|A0A1W2PRZ7_HUMAN,tr|A0A140T9H1|A0A140T9H1_HUMAN,tr|A0A1W2PPH7|A0A1W2PPH7_HUMAN,tr|A0A1W2PQD4|A0A1W2PQD4_HUMAN,tr|A0A140T9U4|A0A140T9U4_HUMAN,tr|A0A1W2PP34|A0A1W2PP34_HUMAN,tr|A0A1X7SBS1|A0A1X7SBS1_HUMAN,tr|A0A140T9F8|A0A140T9F8_HUMAN,tr|J3KQ99|J3KQ99_HUMAN" 24 856.5131 0.99 11713 10075 2 856.511121 429.2638 "HLA class II histocompatibility antigen, DP alpha 1 chain OS=Homo sapiens OX=9606 GN=HLA-DPA1 PE=1 SV=1" 9.75 2379.3 - 4.02E+08 - - - -2.2533 - 1.899 0.131 - 261.2 1 1 0 -0.0019 7 0 0 0 1.72E+10 1.74E+10 - - - 2.04 0.9997 221125_WJC_METTL3_EV_vs_WT_F02.10077.10077.2 0.00389 16-Sep R.TVPLYESPR[166.11].K "sp|Q16531|DDB1_HUMAN,tr|A0A7P0TAK7|A0A7P0TAK7_HUMAN,tr|A0A7P0T870|A0A7P0T870_HUMAN,tr|A0A7P0TB30|A0A7P0TB30_HUMAN,tr|A0A7P0Z3Z5|A0A7P0Z3Z5_HUMAN,tr|F5GY55|F5GY55_HUMAN,tr|A0A7P0Z4B9|A0A7P0Z4B9_HUMAN,tr|A0A7P0T965|A0A7P0T965_HUMAN" 8 1070.5636 1 11714 10077 2 1070.563654 536.2891 DNA damage-binding protein 1 OS=Homo sapiens OX=9606 GN=DDB1 PE=1 SV=1 5.66 2379.5 - 556622 - - - 0.0691 - 1.529 0.431 - 283.7 1 2 0 0.0001 9 0 0 0 5.31E+07 5.31E+07 - - - 3.4528 0.9995 221125_WJC_METTL3_EV_vs_WT_F02.10082.10082.2 0.00177 12-Aug R.WTETYVR[166.11].W "sp|P55884|EIF3B_HUMAN,tr|C9JQN7|C9JQN7_HUMAN,tr|C9JZG1|C9JZG1_HUMAN" 3 963.469 1.16 11715 10082 2 963.468029 482.7418 Eukaryotic translation initiation factor 3 subunit B OS=Homo sapiens OX=9606 GN=EIF3B PE=1 SV=3 6 2380.2 - 3.03E+06 - - - -0.957 - 1.548 0.379 - 327.6 1 2 0 -0.0009 7 0 0 0 1.66E+08 1.43E+08 - - - 3.2245 0.9974 221125_WJC_METTL3_EV_vs_WT_F02.10084.10084.2 0.0125 12-Jun R.WTETYVR.W "sp|P55884|EIF3B_HUMAN,tr|C9JQN7|C9JQN7_HUMAN,tr|C9JZG1|C9JZG1_HUMAN" 3 953.4607 1.16 11717 10084 2 953.459576 477.7376 Eukaryotic translation initiation factor 3 subunit B OS=Homo sapiens OX=9606 GN=EIF3B PE=1 SV=3 6 2380.3 - 3.82E+06 - - - -1.1589 - 1.26 0.274 - 172.8 1 2 0 -0.0011 7 0 0 0 1.66E+08 1.43E+08 - - - 1.7967 0.846 221125_WJC_METTL3_EV_vs_WT_F02.10088.10088.2 0.379 12-Jul K.KPELVIS.Y "sp|P78347|GTF2I_HUMAN,tr|A0A494C1K3|A0A494C1K3_HUMAN" 2 784.4695 1.3 11719 10088 2 784.467642 393.242 General transcription factor II-I OS=Homo sapiens OX=9606 GN=GTF2I PE=1 SV=2 6 2380.8 - 1.51E+06 - - - -2.3111 - 1.544 0.251 - 158.4 1 1 0 -0.0018 7 0 0 0 1.13E+08 8.69E+07 - - - 2.2707 0.9993 221125_WJC_METTL3_EV_vs_WT_F02.10095.10095.2 0.00692 18-Oct R.VAEELVAAAR[166.11].E "sp|P49593|PPM1F_HUMAN,tr|B5MCT7|B5MCT7_HUMAN" 2 1037.5745 1.83 11723 10095 2 1037.573004 519.7945 Protein phosphatase 1F OS=Homo sapiens OX=9606 GN=PPM1F PE=1 SV=3 4.53 2381.7 - 651863 - - - -1.4216 - 1.974 0.285 - 348 1 2 0 -0.0015 10 0 0 0 6.71E+07 3.67E+07 - - - 3.0438 0.9975 221125_WJC_METTL3_EV_vs_WT_F02.10098.10098.2 0.0563 14-Jul K.NIILEEGK[136.11].E "sp|P23528|COF1_HUMAN,tr|E9PP50|E9PP50_HUMAN,tr|G3V1A4|G3V1A4_HUMAN,tr|E9PQB7|E9PQB7_HUMAN,tr|E9PK25|E9PK25_HUMAN,tr|E9PLJ3|E9PLJ3_HUMAN,tr|E9PS23|E9PS23_HUMAN" 7 922.5215 2.1 11724 10098 2 922.519906 462.268 Cofilin-1 OS=Homo sapiens OX=9606 GN=CFL1 PE=1 SV=3 4.53 2382.1 - 3.62E+06 - - - -1.7246 - 1.497 0.249 - 163.4 1 2 0 -0.0016 8 0 0 0 4.46E+08 2.12E+08 - - - 2.0964 0.9998 221125_WJC_METTL3_EV_vs_WT_F02.10100.10100.2 0.00123 20-Dec K.LVVVGAGGVGK[136.11].S "sp|P01111|RASN_HUMAN,sp|P01112|RASH_HUMAN,sp|P01116|RASK_HUMAN,tr|A0A804HKM6|A0A804HKM6_HUMAN,tr|G3V4K2|G3V4K2_HUMAN,tr|A0A804HJ06|A0A804HJ06_HUMAN,tr|G3V5T7|G3V5T7_HUMAN" 7 962.6004 0.95 11726 10100 2 962.59899 482.3075 GTPase NRas OS=Homo sapiens OX=9606 GN=NRAS PE=1 SV=1 8.75 2382.2 - 2.14E+06 - - - -1.4814 - 2.307 0.449 - 460.2 1 2 0 -0.0014 11 0 0 0 1.34E+08 1.41E+08 - - - 4.6183 0.9998 221125_WJC_METTL3_EV_vs_WT_F02.10102.10102.2 0.022 13/18 R.VAEELVAAAR.E "sp|P49593|PPM1F_HUMAN,tr|B5MCT7|B5MCT7_HUMAN" 2 1027.5662 1.83 11728 10102 2 1027.56697 514.7904 Protein phosphatase 1F OS=Homo sapiens OX=9606 GN=PPM1F PE=1 SV=3 4.53 2382.5 - 760442 - - - 0.7406 - 2.63 0.368 - 715.4 1 2 0 0.0008 10 0 0 0 6.73E+07 3.67E+07 - - - 4.458 0.9991 221125_WJC_METTL3_EV_vs_WT_F02.10106.10106.2 0.0284 20-Oct K.LVVVGAGGVGK.S "sp|P01111|RASN_HUMAN,sp|P01112|RASH_HUMAN,sp|P01116|RASK_HUMAN,tr|A0A804HKM6|A0A804HKM6_HUMAN,tr|G3V4K2|G3V4K2_HUMAN,tr|A0A804HJ06|A0A804HJ06_HUMAN,tr|G3V5T7|G3V5T7_HUMAN" 7 954.5862 0.95 11731 10106 2 954.585006 478.3004 GTPase NRas OS=Homo sapiens OX=9606 GN=NRAS PE=1 SV=1 8.75 2382.9 - 1.63E+06 - - - -1.2676 - 1.659 0.32 - 252.4 1 2 0 -0.0012 11 0 0 0 1.34E+08 1.41E+08 - - - 2.7736 0.984 221125_WJC_METTL3_EV_vs_WT_F02.10121.10121.2 0.559 20-Aug R.VLPGQAVTGVR[166.11].G "sp|Q8TAT5|NEIL3_HUMAN,tr|D6RAV1|D6RAV1_HUMAN" 2 1105.6483 0.82 11739 10121 2 1105.648433 553.8314 Endonuclease 8-like 3 OS=Homo sapiens OX=9606 GN=NEIL3 PE=1 SV=3 9.72 2384.9 - 194619 - - - 0.1085 - 1.357 0.06 - 170.8 1 2 0 0.0001 11 0 0 0 1.15E+07 1.41E+07 - - - 0.31 0.9993 221125_WJC_METTL3_EV_vs_WT_F02.10124.10124.2 0.000334 14-Jul K.FFAPEC[160.03]GR[166.11].C "sp|Q96HC4|PDLI5_HUMAN,tr|H0Y8Y3|H0Y8Y3_HUMAN,tr|A0A0A0MSP3|A0A0A0MSP3_HUMAN" 3 992.4414 1.01 11740 10124 2 992.439068 497.228 PDZ and LIM domain protein 5 OS=Homo sapiens OX=9606 GN=PDLIM5 PE=1 SV=5 5.99 2385.4 - 305388 - - - -2.3064 - 1.487 0.464 - 188.3 1 2 0 -0.0023 8 0 0 0 1.18E+07 1.16E+07 - - - 3.664 0.884 221125_WJC_METTL3_EV_vs_WT_F02.10128.10128.2 0.0302 12-Jun F.NVVVFDK[136.11].E "sp|Q8N807|PDILT_HUMAN,sp|Q9UMS4|PRP19_HUMAN" 2 827.4633 1.3 11742 10128 2 827.463791 414.7389 Protein disulfide-isomerase-like protein of the testis OS=Homo sapiens OX=9606 GN=PDILT PE=1 SV=2 5.84 2385.8 - 4.99E+06 - - - 0.649 - 1.221 0.292 - 186.2 1 1 0 0.0005 7 0 0 0 9.34E+08 7.18E+08 - - - 1.8302 0.8531 221125_WJC_METTL3_EV_vs_WT_F02.10129.10129.2 0.0363 12-Jul F.NVVVFDK.E "sp|Q8N807|PDILT_HUMAN,sp|Q9UMS4|PRP19_HUMAN" 2 819.4491 1.29 11743 10129 2 819.450356 410.7318 Protein disulfide-isomerase-like protein of the testis OS=Homo sapiens OX=9606 GN=PDILT PE=1 SV=2 5.84 2385.9 - 4.98E+06 - - - 1.5889 - 1.366 0.264 - 238.9 1 1 0 0.0013 7 0 0 0 9.35E+08 7.22E+08 - - - 1.9787 0.9993 221125_WJC_METTL3_EV_vs_WT_F02.10132.10132.2 0.776 14-Sep K.IVDVIGEK[136.11].L "sp|P13861|KAP2_HUMAN,tr|H7C4A9|H7C4A9_HUMAN" 2 879.5157 1.78 11745 10132 2 879.514828 440.7651 cAMP-dependent protein kinase type II-alpha regulatory subunit OS=Homo sapiens OX=9606 GN=PRKAR2A PE=1 SV=2 4.37 2386.2 - 8.73E+06 - - - -0.9733 - 1.817 0.273 - 234.7 1 2 0 -0.0009 8 0 0 0 6.08E+08 3.41E+08 - - - 2.8582 0.9989 221125_WJC_METTL3_EV_vs_WT_F02.10133.10133.2 0.836 12-Jul R.DMLLANK.V "sp|Q8NHW5|RLA0L_HUMAN,sp|P05388|RLA0_HUMAN,tr|G3V210|G3V210_HUMAN,tr|F8VU65|F8VU65_HUMAN,tr|F8VWV4|F8VWV4_HUMAN,tr|F8VWS0|F8VWS0_HUMAN,tr|F8VS58|F8VS58_HUMAN,tr|F8VW21|F8VW21_HUMAN,tr|F8VZS0|F8VZS0_HUMAN,tr|F8VRK7|F8VRK7_HUMAN,tr|F8VQY6|F8VQY6_HUMAN,tr|F8VPE8|F8VPE8_HUMAN" 12 803.4211 1.13 11746 10133 2 803.421135 402.7178 60S acidic ribosomal protein P0-like OS=Homo sapiens OX=9606 GN=RPLP0P6 PE=5 SV=1 5.84 2386.3 - 7.46E+06 - - - 0.0124 - 1.66 0.221 - 276.9 1 2 0 0 7 0 0 0 3.98E+08 3.52E+08 - - - 2.2792 0.8999 221125_WJC_METTL3_EV_vs_WT_F02.10138.10138.2 28.2 12-Jun R.KSPLLGR[166.11].F "sp|O43897|TLL1_HUMAN,tr|E9PD25|E9PD25_HUMAN" 2 779.4893 - 11747 10138 2 779.488156 390.7519 Tolloid-like protein 1 OS=Homo sapiens OX=9606 GN=TLL1 PE=1 SV=1 11 2387 - 674534 - - - -1.4586 - 1.108 0.046 - 127.5 6 2 0 -0.0011 7 0 0 0 - - - - - -0.6422 0.9958 221125_WJC_METTL3_EV_vs_WT_F02.10145.10145.2 0.115 14-Jul R.LEYGGLGR.E sp|Q96DG6|CMBL_HUMAN 1 863.4501 0.77 11751 10145 2 863.448681 432.7323 Carboxymethylenebutenolidase homolog OS=Homo sapiens OX=9606 GN=CMBL PE=1 SV=1 6 2387.9 - 1.13E+07 - - - -1.6631 - 1.272 0.253 - 170.3 1 2 0 -0.0014 8 0 0 0 4.69E+08 6.06E+08 - - - 1.6348 0.9981 221125_WJC_METTL3_EV_vs_WT_F02.10147.10147.2 0.0232 14-Jul K.LLLAPSSK[136.11].K "sp|Q9HCE1|MOV10_HUMAN,tr|Q5JR04|Q5JR04_HUMAN" 2 835.5259 0.92 11752 10147 2 835.526096 418.7702 Helicase MOV-10 OS=Homo sapiens OX=9606 GN=MOV10 PE=1 SV=2 8.75 2388.1 - 1.95E+06 - - - 0.2896 - 1.298 0.274 - 118.2 1 2 0 0.0002 8 0 0 0 6.79E+07 7.39E+07 - - - 1.8513 0.9989 221125_WJC_METTL3_EV_vs_WT_F02.10149.10149.2 0.0145 16-Aug K.IVVVTAGVR[166.11].Q "sp|P07195|LDHB_HUMAN,tr|A8MW50|A8MW50_HUMAN,tr|A0A3B3IS95|A0A3B3IS95_HUMAN,tr|C9J7H8|C9J7H8_HUMAN,tr|F5H793|F5H793_HUMAN,tr|A0A5F9ZHM4|A0A5F9ZHM4_HUMAN" 6 922.5839 0.7 11754 10149 2 922.582159 462.2992 L-lactate dehydrogenase B chain OS=Homo sapiens OX=9606 GN=LDHB PE=1 SV=2 9.75 2388.2 - 4.23E+06 - - - -1.9109 - 1.728 0.309 - 206 1 2 0 -0.0018 9 0 0 0 1.25E+08 1.80E+08 - - - 2.9051 0.999 221125_WJC_METTL3_EV_vs_WT_F02.10153.10153.2 0.0633 14-Sep K.FIDQVVEK[136.11].L "sp|O95453|PARN_HUMAN,tr|A0A494C0Q6|A0A494C0Q6_HUMAN,tr|A0A494BZW7|A0A494BZW7_HUMAN,tr|A0A494C0Q2|A0A494C0Q2_HUMAN,tr|A0A494BZU6|A0A494BZU6_HUMAN,tr|A0A494C1G3|A0A494C1G3_HUMAN,tr|A0A494C002|A0A494C002_HUMAN,tr|A0A494C1K5|A0A494C1K5_HUMAN,tr|A0A494C156|A0A494C156_HUMAN,tr|F5H1Z4|F5H1Z4_HUMAN,tr|A0A494C1N1|A0A494C1N1_HUMAN,tr|A0A494C0W0|A0A494C0W0_HUMAN,tr|A0A494C0P9|A0A494C0P9_HUMAN,tr|A0A494C0K5|A0A494C0K5_HUMAN,tr|H3BRK1|H3BRK1_HUMAN" 15 984.5371 0.99 11755 10153 2 984.536377 493.2758 Poly(A)-specific ribonuclease PARN OS=Homo sapiens OX=9606 GN=PARN PE=1 SV=1 4.37 2388.8 - 811022 - - - -0.7821 - 1.379 0.328 - 202.6 1 2 0 -0.0008 8 0 0 0 2.66E+07 2.67E+07 - - - 2.4326 0.9954 221125_WJC_METTL3_EV_vs_WT_F02.10155.10155.2 0.1 14-Jul R.TMIISPER.L "sp|O75533|SF3B1_HUMAN,tr|B4DGZ4|B4DGZ4_HUMAN,tr|A0A494C1M2|A0A494C1M2_HUMAN" 3 945.4954 1.11 11757 10155 2 945.495094 473.755 Splicing factor 3B subunit 1 OS=Homo sapiens OX=9606 GN=SF3B1 PE=1 SV=3 5.66 2389 - 1.75E+06 - - - -0.2729 - 1.375 0.157 - 178.2 1 2 0 -0.0003 8 0 0 0 7.99E+07 7.19E+07 - - - 1.161 0.9994 221125_WJC_METTL3_EV_vs_WT_F02.10166.10166.2 0.00328 16-Aug K.IVVVTAGVR.Q "sp|P07195|LDHB_HUMAN,tr|A8MW50|A8MW50_HUMAN,tr|A0A3B3IS95|A0A3B3IS95_HUMAN,tr|C9J7H8|C9J7H8_HUMAN,tr|F5H793|F5H793_HUMAN,tr|A0A5F9ZHM4|A0A5F9ZHM4_HUMAN" 6 912.5757 0.7 11762 10166 2 912.574829 457.2951 L-lactate dehydrogenase B chain OS=Homo sapiens OX=9606 GN=LDHB PE=1 SV=2 9.75 2390.3 - 3.64E+06 - - - -0.9018 - 1.846 0.303 - 217.6 1 2 0 -0.0008 9 0 0 0 1.25E+08 1.80E+08 - - - 3.0522 0.9964 221125_WJC_METTL3_EV_vs_WT_F02.10168.10168.2 0.173 14-Jun K.MVLNETYR[166.11].N "sp|A5YKK6|CNOT1_HUMAN,tr|H3BVC9|H3BVC9_HUMAN" 2 1034.5094 0.67 11764 10168 2 1034.507912 518.262 CCR4-NOT transcription complex subunit 1 OS=Homo sapiens OX=9606 GN=CNOT1 PE=1 SV=2 5.75 2390.5 - 599051 - - - -1.4732 - 1.267 0.257 - 123.6 1 2 0 -0.0015 8 0 0 0 1.08E+07 1.62E+07 - - - 1.6525 0.9948 221125_WJC_METTL3_EV_vs_WT_F02.10171.10171.2 0.377 12-Jun K.LVDNWAR[166.11].D "sp|Q9H4A3|WNK1_HUMAN,tr|F5GWT4|F5GWT4_HUMAN,tr|A0A6Q8PFM0|A0A6Q8PFM0_HUMAN" 3 882.4587 3.28 11765 10171 2 882.458975 442.2366 Serine\threonine-protein kinase WNK1 OS=Homo sapiens OX=9606 GN=WNK1 PE=1 SV=2 5.84 2390.9 - 1.29E+06 - - - 0.2878 - 0.99 0.283 - 94.2 1 2 0 0.0003 7 0 0 0 6.72E+08 2.05E+08 - - - 1.0993 0.9998 221125_WJC_METTL3_EV_vs_WT_F02.10175.10175.2 0.00919 16-Oct R.LNDFASTVR.L "sp|P20674|COX5A_HUMAN,tr|H3BNX8|H3BNX8_HUMAN,tr|H3BV69|H3BV69_HUMAN,tr|H3BRM5|H3BRM5_HUMAN" 4 1021.5193 1.91 11767 10175 2 1021.518889 511.7669 "Cytochrome c oxidase subunit 5A, mitochondrial OS=Homo sapiens OX=9606 GN=COX5A PE=1 SV=2" 5.84 2391.3 - 898299 - - - -0.3622 - 2.141 0.374 - 344 1 2 0 -0.0004 9 0 0 0 3.65E+08 1.92E+08 - - - 4.0057 0.9966 221125_WJC_METTL3_EV_vs_WT_F02.10177.10177.2 0.0821 16-Sep R.LNDFASTVR[166.11].L "sp|P20674|COX5A_HUMAN,tr|H3BNX8|H3BNX8_HUMAN,tr|H3BV69|H3BV69_HUMAN,tr|H3BRM5|H3BRM5_HUMAN" 4 1031.5275 1.91 11768 10177 2 1031.529228 516.771 "Cytochrome c oxidase subunit 5A, mitochondrial OS=Homo sapiens OX=9606 GN=COX5A PE=1 SV=2" 5.84 2391.6 - 816512 - - - 1.6471 - 1.563 0.209 - 268.2 1 2 0 0.0017 9 0 0 0 3.65E+08 1.91E+08 - - - 1.8762 0.9998 221125_WJC_METTL3_EV_vs_WT_F02.10180.10180.2 0.000746 18-Oct K.MLVSGAGDIK[136.11].L "sp|Q92526|TCPW_HUMAN,sp|P40227|TCPZ_HUMAN" 2 997.5358 0.35 11770 10180 2 997.53628 499.7752 T-complex protein 1 subunit zeta-2 OS=Homo sapiens OX=9606 GN=CCT6B PE=1 SV=5 5.59 2391.8 - 7.70E+06 - - - 0.5143 - 1.965 0.437 - 288.4 1 2 0 0.0005 10 0 0 0 1.39E+09 3.98E+09 - - - 4.154 0.966 221125_WJC_METTL3_EV_vs_WT_F02.10181.10181.2 0.138 16-Aug R.IIALDGDTK[136.11].N "sp|P29401|TKT_HUMAN,tr|A0A0B4J1R6|A0A0B4J1R6_HUMAN" 2 952.5321 1.63 11771 10181 2 952.526667 477.2733 Transketolase OS=Homo sapiens OX=9606 GN=TKT PE=1 SV=3 4.21 2391.9 - 1.67E+06 - - - -5.6639 - 1.659 0.237 - 136.6 1 2 0 -0.0054 9 0 0 0 8.89E+07 5.44E+07 - - - 2.2543 0.9991 221125_WJC_METTL3_EV_vs_WT_F02.10185.10185.2 0.117 12-Jul K.VSTDLLR[166.11].E "sp|Q96HS1|PGAM5_HUMAN,tr|F5GXG4|F5GXG4_HUMAN" 2 812.4631 1.08 11773 10185 2 812.462428 407.2388 "Serine\threonine-protein phosphatase PGAM5, mitochondrial OS=Homo sapiens OX=9606 GN=PGAM5 PE=1 SV=2" 5.81 2392.4 - 6.28E+06 - - - -0.8739 - 1.369 0.35 - 171.7 1 2 0 -0.0007 7 0 0 0 3.09E+08 2.86E+08 - - - 2.6211 0.9968 221125_WJC_METTL3_EV_vs_WT_F02.10187.10187.2 0.214 12-Jul K.VSTDLLR.E "sp|Q96HS1|PGAM5_HUMAN,tr|F5GXG4|F5GXG4_HUMAN" 2 802.4549 0.99 11775 10187 2 802.453906 402.2347 "Serine\threonine-protein phosphatase PGAM5, mitochondrial OS=Homo sapiens OX=9606 GN=PGAM5 PE=1 SV=2" 5.81 2392.6 - 7.40E+06 - - - -1.1988 - 1.331 0.228 - 181.2 1 2 0 -0.001 7 0 0 0 3.09E+08 3.12E+08 - - - 1.6307 0.9976 221125_WJC_METTL3_EV_vs_WT_F02.10192.10192.2 0.699 14-Sep R.QLYEEEIR.E "sp|P05787|K2C8_HUMAN,tr|F8VUG2|F8VUG2_HUMAN,tr|F8W1U3|F8W1U3_HUMAN" 3 1078.5295 1.54 11777 10192 2 1078.528796 540.272 "Keratin, type II cytoskeletal 8 OS=Homo sapiens OX=9606 GN=KRT8 PE=1 SV=7" 4.25 2393.3 - 663171 - - - -0.6425 - 1.695 0.143 - 366.9 1 2 0 -0.0007 8 0 0 0 2.51E+07 1.64E+07 - - - 1.6884 0.9947 221125_WJC_METTL3_EV_vs_WT_F02.10193.10193.2 0.0195 14-Aug R.QLYEEEIR[166.11].E "sp|P05787|K2C8_HUMAN,tr|F8VUG2|F8VUG2_HUMAN,tr|F8W1U3|F8W1U3_HUMAN" 3 1088.5378 1.54 11778 10193 2 1088.538239 545.2762 "Keratin, type II cytoskeletal 8 OS=Homo sapiens OX=9606 GN=KRT8 PE=1 SV=7" 4.25 2393.4 - 512461 - - - 0.441 - 1.501 0.114 - 236.5 1 2 0 0.0005 8 0 0 0 2.51E+07 1.64E+07 - - - 1.1077 0.9899 221125_WJC_METTL3_EV_vs_WT_F02.10194.10194.2 0.288 14-Jul K.EVFAEAVR.A sp|P84095|RHOG_HUMAN 1 919.4763 0.81 11779 10194 2 919.474712 460.7454 Rho-related GTP-binding protein RhoG OS=Homo sapiens OX=9606 GN=RHOG PE=1 SV=1 4.53 2393.5 - 3.13E+06 - - - -1.7608 - 1.525 0.097 - 186.5 1 2 0 -0.0016 8 0 0 0 1.14E+08 1.40E+08 - - - 1.0296 0.9997 221125_WJC_METTL3_EV_vs_WT_F02.10201.10201.2 1.46E-05 14-Aug K.YETELAMR.Q "sp|P05783|K1C18_HUMAN,tr|F8VZY9|F8VZY9_HUMAN" 2 1011.4695 1.86 11783 10201 2 1011.468031 506.742 "Keratin, type I cytoskeletal 18 OS=Homo sapiens OX=9606 GN=KRT18 PE=1 SV=2" 4.53 2394.3 - 1.09E+06 - - - -1.484 - 1.677 0.465 - 184.3 1 2 0 -0.0015 8 0 0 0 3.43E+07 1.84E+07 - - - 4.0343 0.935 221125_WJC_METTL3_EV_vs_WT_F02.10202.10202.2 0.00141 14-Aug E.AALSPTFR[166.11].S "sp|Q86U44|MTA70_HUMAN,tr|B4E349|B4E349_HUMAN,tr|F5H6D8|F5H6D8_HUMAN,tr|B4DTN4|B4DTN4_HUMAN" 4 871.4791 0.1 11784 10202 2 871.476818 436.7468 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 9.79 2394.3 - 7.51E+06 - - - -2.6438 - 1.552 0.417 - 173.4 1 1 0 -0.0023 8 0 0 0 2.19E+07 2.29E+08 - - - 3.4459 0.9869 221125_WJC_METTL3_EV_vs_WT_F02.10203.10203.2 0.241 16-Jul R.GIVGGGMMR.D "sp|Q9UN86|G3BP2_HUMAN,tr|A0A7I2V647|A0A7I2V647_HUMAN,tr|A0A7I2YQD9|A0A7I2YQD9_HUMAN,tr|A0A7I2V3P9|A0A7I2V3P9_HUMAN" 4 876.431 1.24 11785 10203 2 876.42923 439.2228 Ras GTPase-activating protein-binding protein 2 OS=Homo sapiens OX=9606 GN=G3BP2 PE=1 SV=2 9.75 2394.4 - 3.23E+06 - - - -1.9945 - 1.083 0.228 - 153.2 1 2 0 -0.0017 9 0 0 0 3.80E+08 3.08E+08 - - - 0.9551 0.991 221125_WJC_METTL3_EV_vs_WT_F02.10206.10206.2 0.146 14-Jun R.LSPVPVPR.A "sp|Q9UKM9|RALY_HUMAN,tr|Q5QPM0|Q5QPM0_HUMAN,tr|Q5QPM1|Q5QPM1_HUMAN,tr|Q5QPL9|Q5QPL9_HUMAN" 4 863.5229 1.38 11786 10206 2 863.519967 432.7687 RNA-binding protein Raly OS=Homo sapiens OX=9606 GN=RALY PE=1 SV=1 9.75 2394.7 - 5.98E+06 - - - -3.3827 - 1.015 0.396 - 118.7 1 2 0 -0.0029 8 0 0 0 3.01E+08 2.18E+08 - - - 2.0098 0.9983 221125_WJC_METTL3_EV_vs_WT_F02.10210.10210.2 0.113 14-Jul R.EGLEETLR.N sp|P07196|NFL_HUMAN 1 945.4767 2.5 11787 10210 2 945.47594 473.7456 Neurofilament light polypeptide OS=Homo sapiens OX=9606 GN=NEFL PE=1 SV=3 4.25 2395.3 - 3.03E+06 - - - -0.8303 - 1.389 0.27 - 141 1 2 0 -0.0008 8 0 0 0 1.09E+08 4.38E+07 - - - 2.026 0.9974 221125_WJC_METTL3_EV_vs_WT_F02.10214.10214.2 0.00158 16-Sep K.TLATTLAPR[166.11].V "sp|Q9H583|HEAT1_HUMAN,tr|Q5T3Q7|Q5T3Q7_HUMAN" 2 952.5581 3.86 11789 10214 2 952.561794 477.2863 HEAT repeat-containing protein 1 OS=Homo sapiens OX=9606 GN=HEATR1 PE=1 SV=3 9.41 2395.8 - 1.22E+06 - - - 3.8769 - 1.755 0.397 - 211.9 1 2 0 0.0037 9 0 0 0 1.83E+08 4.73E+07 - - - 3.5993 0.971 221125_WJC_METTL3_EV_vs_WT_F02.10216.10216.2 2.85 16-May K.IINTPEVVR.V "sp|Q9H4M9|EHD1_HUMAN,tr|C9JC03|C9JC03_HUMAN,tr|C9J2Z4|C9J2Z4_HUMAN,tr|C9JDQ8|C9JDQ8_HUMAN,tr|A0A024R571|A0A024R571_HUMAN" 5 1039.6026 0.96 11790 10216 2 1039.602561 520.8086 EH domain-containing protein 1 OS=Homo sapiens OX=9606 GN=EHD1 PE=1 SV=2 6 2396 - 517953 - - - -0.0327 - 1.121 0.128 - 47.2 8 2 0 0 9 0 0 0 7.83E+07 8.17E+07 - - - -0.0866 0.9972 221125_WJC_METTL3_EV_vs_WT_F02.10224.10224.2 0.0474 14-Jul K.LIPDSIGK.D "sp|P61247|RS3A_HUMAN,tr|D6R9B6|D6R9B6_HUMAN,tr|H0Y9Y4|H0Y9Y4_HUMAN,tr|D6RB09|D6RB09_HUMAN,tr|D6RAT0|D6RAT0_HUMAN,tr|D6RG13|D6RG13_HUMAN" 6 841.4909 1.2 11795 10224 2 841.491833 421.7527 40S ribosomal protein S3a OS=Homo sapiens OX=9606 GN=RPS3A PE=1 SV=2 5.84 2396.7 - 6.98E+06 - - - 1.0862 - 1.281 0.27 - 136.6 1 2 0 0.0009 8 0 0 0 3.59E+08 3.00E+08 - - - 1.7818 0.9828 221125_WJC_METTL3_EV_vs_WT_F02.10227.10227.2 0.857 12-Jun K.IELETYK[136.11].L sp|Q16204|CCDC6_HUMAN 1 902.484 0.73 11797 10227 2 902.480997 452.2493 Coiled-coil domain-containing protein 6 OS=Homo sapiens OX=9606 GN=CCDC6 PE=1 SV=2 4.53 2397.1 - 784536 - - - -3.3818 - 1.458 0.17 - 89.9 1 2 0 -0.0031 7 0 0 0 2.38E+07 3.28E+07 - - - 1.4904 0.9939 221125_WJC_METTL3_EV_vs_WT_F02.10231.10231.2 0.361 12-Jun K.SMIEISR[166.11].T "sp|P49368|TCPG_HUMAN,tr|E9PM09|E9PM09_HUMAN,tr|Q5SZW8|Q5SZW8_HUMAN,tr|E9PRC8|E9PRC8_HUMAN,tr|B4DUR8|B4DUR8_HUMAN,tr|Q5SZX9|Q5SZX9_HUMAN,tr|Q5SZX6|Q5SZX6_HUMAN" 7 844.4352 0.32 11799 10231 2 844.434858 423.2249 T-complex protein 1 subunit gamma OS=Homo sapiens OX=9606 GN=CCT3 PE=1 SV=4 5.72 2397.6 - 3.96E+06 - - - -0.4145 - 1.229 0.173 - 164.8 1 2 0 -0.0003 7 0 0 0 2.08E+08 6.48E+08 - - - 0.972 0.9861 221125_WJC_METTL3_EV_vs_WT_F02.10232.10232.2 0.0126 16-Sep Y.MAIDGVAPR.A sp|Q9H0D6|XRN2_HUMAN 1 928.48 1.78 11800 10232 2 928.479546 465.2473 5'-3' exoribonuclease 2 OS=Homo sapiens OX=9606 GN=XRN2 PE=1 SV=1 5.59 2397.7 - 1.41E+06 - - - -0.5288 - 2.026 0.383 - 237.6 1 1 0 -0.0005 9 0 0 0 1.04E+08 5.81E+07 - - - 3.9124 0.9991 221125_WJC_METTL3_EV_vs_WT_F02.10234.10234.2 1.56E-05 16-Sep R.LYAMQTGMK.L "sp|Q9NP79|VTA1_HUMAN,tr|A0A087WY55|A0A087WY55_HUMAN" 2 1041.4987 1.51 11802 10234 2 1041.495482 521.7566 Vacuolar protein sorting-associated protein VTA1 homolog OS=Homo sapiens OX=9606 GN=VTA1 PE=1 SV=1 8.59 2397.9 - 657789 - - - -3.1119 - 1.702 0.494 - 209.4 1 2 0 -0.0032 9 0 0 0 7.97E+07 5.28E+07 - - - 4.2272 0.9921 221125_WJC_METTL3_EV_vs_WT_F02.10238.10238.2 0.000206 16-Sep R.LYAMQTGMK[136.11].L "sp|Q9NP79|VTA1_HUMAN,tr|A0A087WY55|A0A087WY55_HUMAN" 2 1049.5129 1.51 11803 10238 2 1049.506612 525.7637 Vacuolar protein sorting-associated protein VTA1 homolog OS=Homo sapiens OX=9606 GN=VTA1 PE=1 SV=1 8.59 2398.5 - 871894 - - - -6.0133 - 1.829 0.444 - 221.1 1 2 0 -0.0063 9 0 0 0 7.97E+07 5.28E+07 - - - 4.0651 0.9882 221125_WJC_METTL3_EV_vs_WT_F02.10250.10250.2 0.0408 16-Aug R.GPLVNASLR.A "sp|O14744|ANM5_HUMAN,tr|H0YJ77|H0YJ77_HUMAN,tr|H0YJX6|H0YJX6_HUMAN" 3 925.5345 2.72 11807 10250 2 925.52963 463.7745 Protein arginine N-methyltransferase 5 OS=Homo sapiens OX=9606 GN=PRMT5 PE=1 SV=4 9.75 2400 - 552788 - - - -5.278 - 1.77 0.313 - 301.4 1 2 0 -0.0049 9 0 0 0 5.04E+09 1.85E+09 - - - 3.0032 0.9981 221125_WJC_METTL3_EV_vs_WT_F02.10259.10259.2 0.041 12-Sep K.TLVDIAK.S "sp|Q99832|TCPH_HUMAN,sp|Q9H2S1|KCNN2_HUMAN,tr|F8WAM2|F8WAM2_HUMAN,tr|A0A3F2YNY5|A0A3F2YNY5_HUMAN,tr|A0A0J9YW81|A0A0J9YW81_HUMAN,tr|A0A669KBH3|A0A669KBH3_HUMAN" 6 758.4538 0.14 11812 10259 2 758.451907 380.2342 T-complex protein 1 subunit eta OS=Homo sapiens OX=9606 GN=CCT7 PE=1 SV=2 5.5 2401.1 - 2.84E+06 - - - -2.5025 - 1.702 0.284 - 278.4 1 2 0 -0.0019 7 0 0 0 7.47E+08 5.37E+09 - - - 2.8231 0.9951 221125_WJC_METTL3_EV_vs_WT_F02.10260.10260.2 0.00623 16-Oct R.GPLVNASLR[166.11].A "sp|O14744|ANM5_HUMAN,tr|H0YJ77|H0YJ77_HUMAN,tr|H0YJX6|H0YJX6_HUMAN" 3 935.5428 2.72 11813 10260 2 935.539501 468.7787 Protein arginine N-methyltransferase 5 OS=Homo sapiens OX=9606 GN=PRMT5 PE=1 SV=4 9.75 2401.2 - 1.90E+06 - - - -3.5103 - 2.007 0.213 - 345.6 1 2 0 -0.0033 9 0 0 0 5.04E+09 1.85E+09 - - - 2.6286 0.9379 221125_WJC_METTL3_EV_vs_WT_F02.10268.10268.2 4.02 12-Jul R.AVNLNLR.A "sp|Q9BSJ6|PIMRE_HUMAN,tr|I3L156|I3L156_HUMAN,tr|I3L419|I3L419_HUMAN,tr|I3L427|I3L427_HUMAN" 4 798.4712 0.43 11816 10268 2 798.469938 400.2429 Protein PIMREG OS=Homo sapiens OX=9606 GN=PIMREG PE=1 SV=1 9.79 2402.3 - 1.07E+06 - - - -1.563 - 1.201 0.013 - 175.7 1 2 0 -0.0012 7 0 0 0 5.83E+07 1.35E+08 - - - -0.283 0.9896 221125_WJC_METTL3_EV_vs_WT_F02.10271.10271.2 0.0913 12-Aug K.IYVGLSK.M sp|O60264|SMCA5_HUMAN 1 778.4589 1.05 11817 10271 2 778.455561 390.2367 SWI\SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A member 5 OS=Homo sapiens OX=9606 GN=SMARCA5 PE=1 SV=1 8.59 2402.6 - 1.84E+06 - - - -4.2764 - 1.449 0.302 - 176 1 2 0 -0.0033 7 0 0 0 9.22E+07 8.77E+07 - - - 2.4457 0.9989 221125_WJC_METTL3_EV_vs_WT_F02.10277.10277.2 0.032 16-Aug K.LTVDSAIAR.D sp|P15924|DESP_HUMAN 1 944.5291 1.76 11819 10277 2 944.527696 473.2718 Desmoplakin OS=Homo sapiens OX=9606 GN=DSP PE=1 SV=3 5.84 2403.4 - 1.04E+07 - - - -1.4812 - 1.595 0.308 - 215.6 1 2 0 -0.0014 9 0 0 0 4.15E+08 2.36E+08 - - - 2.6661 0.9995 221125_WJC_METTL3_EV_vs_WT_F02.10278.10278.2 0.0853 14-Sep R.LLDEEISR[166.11].V sp|Q96PU8|QKI_HUMAN 1 983.5163 2.26 11820 10278 2 983.515645 492.7654 Protein quaking OS=Homo sapiens OX=9606 GN=QKI PE=1 SV=1 4.14 2403.5 - 1.92E+06 - - - -0.6619 - 1.794 0.306 - 238.8 1 2 0 -0.0006 8 0 0 0 4.41E+09 1.95E+09 - - - 3.0636 0.9136 221125_WJC_METTL3_EV_vs_WT_F02.10286.10286.2 1.41 12-May K.ELTSLVK.E "sp|O00422|SAP18_HUMAN,tr|U3KPY7|U3KPY7_HUMAN,tr|H7BZW6|H7BZW6_HUMAN" 3 788.4644 1.28 11826 10286 2 788.46328 395.2395 Histone deacetylase complex subunit SAP18 OS=Homo sapiens OX=9606 GN=SAP18 PE=1 SV=1 6.1 2404.3 - 2.20E+06 - - - -1.3824 - 1.259 0.001 - 82.9 6 2 0 -0.0011 7 0 0 0 1.29E+09 1.01E+09 - - - -0.5698 0.9978 221125_WJC_METTL3_EV_vs_WT_F02.10287.10287.2 0.00128 18-Sep R.YLEAGAAGLR[166.11].W "sp|Q9NZL4|HPBP1_HUMAN,tr|K7EMM7|K7EMM7_HUMAN,tr|K7EL16|K7EL16_HUMAN,tr|K7EN20|K7EN20_HUMAN" 4 1029.5483 0.42 11827 10287 2 1029.545371 515.7814 Hsp70-binding protein 1 OS=Homo sapiens OX=9606 GN=HSPBP1 PE=1 SV=2 6 2404.4 - 903219 - - - -2.81 - 1.768 0.305 - 235.6 1 2 0 -0.0029 10 0 0 0 2.10E+07 5.06E+07 - - - 2.8834 0.9904 221125_WJC_METTL3_EV_vs_WT_F02.10294.10294.2 0.0802 16-Jul R.LYPGSVYGR.L "sp|Q14683|SMC1A_HUMAN,tr|G8JLG1|G8JLG1_HUMAN,tr|A0A6Q8PHC3|A0A6Q8PHC3_HUMAN" 3 1010.5185 1.02 11829 10294 2 1010.514974 506.2665 Structural maintenance of chromosomes protein 1A OS=Homo sapiens OX=9606 GN=SMC1A PE=1 SV=2 8.59 2405.4 - 858803 - - - -3.52 - 1.315 0.299 - 121.1 1 2 0 -0.0036 9 0 0 0 1.53E+08 1.50E+08 - - - 2.0405 0.845 221125_WJC_METTL3_EV_vs_WT_F02.10299.10299.2 0.198 12-Jul G.IIEPSLR[166.11].Q "sp|P62987|RL40_HUMAN,tr|M0R1A4|M0R1A4_HUMAN,tr|M0QZ32|M0QZ32_HUMAN,tr|M0R2S1|M0R2S1_HUMAN,tr|M0R1M6|M0R1M6_HUMAN" 5 836.4995 0.96 11830 10299 2 836.499073 419.257 Ubiquitin-60S ribosomal protein L40 OS=Homo sapiens OX=9606 GN=UBA52 PE=1 SV=2 6 2406.2 - 1.64E+07 - - - -0.538 - 1.455 0.171 - 138.8 1 1 0 -0.0004 7 0 0 0 5.86E+09 6.07E+09 - - - 1.4921 0.9995 221125_WJC_METTL3_EV_vs_WT_F02.10303.10303.2 0.000267 22-Nov R.ALEESNYELEGK.L "sp|P13645|K1C10_HUMAN,tr|A0A1B0GVI3|A0A1B0GVI3_HUMAN" 2 1380.6409 999 11832 10303 2 1380.637667 691.3277 "Keratin, type I cytoskeletal 10 OS=Homo sapiens OX=9606 GN=KRT10 PE=1 SV=6" 4.09 2406.6 - 950810 - - - -2.3344 - 2.172 0.442 - 287.6 1 2 0 -0.0032 12 0 0 0 6.01E+07 0.00E+00 - - - 4.3455 0.9973 221125_WJC_METTL3_EV_vs_WT_F02.10311.10311.2 0.0273 16-Oct K.IINTPEVVR[166.11].V "sp|Q9H4M9|EHD1_HUMAN,tr|C9JC03|C9JC03_HUMAN,tr|C9J2Z4|C9J2Z4_HUMAN,tr|C9JDQ8|C9JDQ8_HUMAN,tr|A0A024R571|A0A024R571_HUMAN" 5 1049.6109 0.94 11833 10311 2 1049.607615 525.8127 EH domain-containing protein 1 OS=Homo sapiens OX=9606 GN=EHD1 PE=1 SV=2 6 2407.8 - 963498 - - - -3.0964 - 1.797 0.294 - 257.5 1 2 0 -0.0032 9 0 0 0 7.86E+07 8.34E+07 - - - 2.9071 0.9986 221125_WJC_METTL3_EV_vs_WT_F02.10315.10315.2 0.0343 14-Aug R.QAGLSYIR.Y "sp|Q5VTU8|AT5EL_HUMAN,sp|P56381|ATP5E_HUMAN" 2 906.4923 1.65 11835 10315 2 906.490423 454.2534 "ATP synthase subunit epsilon-like protein, mitochondrial OS=Homo sapiens OX=9606 GN=ATP5F1EP2 PE=1 SV=1" 8.75 2408.3 - 7.48E+06 - - - -2.0883 - 1.516 0.338 - 222.9 1 2 0 -0.0019 8 0 0 0 3.14E+08 1.91E+08 - - - 2.7917 0.9993 221125_WJC_METTL3_EV_vs_WT_F02.10331.10331.2 0.146 14-Aug K.FAEYGEIK.N "sp|Q9Y5S9|RBM8A_HUMAN,tr|A0A0J9YW13|A0A0J9YW13_HUMAN" 2 955.4651 0.84 11839 10331 2 955.464129 478.7398 RNA-binding protein 8A OS=Homo sapiens OX=9606 GN=RBM8A PE=1 SV=1 4.53 2410.6 - 1.53E+07 - - - -1.0142 - 1.583 0.334 - 157.2 1 2 0 -0.001 8 0 0 0 5.84E+08 6.96E+08 - - - 2.8929 0.9983 221125_WJC_METTL3_EV_vs_WT_F02.10332.10332.2 0.00101 16-Sep R.YLDGLTAER.T sp|P35908|K22E_HUMAN 1 1036.5189 55 11840 10332 2 1036.515335 519.2667 "Keratin, type II cytoskeletal 2 epidermal OS=Homo sapiens OX=9606 GN=KRT2 PE=1 SV=2" 4.37 2410.7 - 2.17E+06 - - - -3.4635 - 1.73 0.416 - 205.1 1 2 0 -0.0036 9 0 0 0 2.41E+08 4.38E+06 - - - 3.6982 0.947 221125_WJC_METTL3_EV_vs_WT_F02.10338.10338.2 0.527 14-Sep K.EHC[160.03]LVGVK[136.11].G sp|Q86U44|MTA70_HUMAN 1 948.4942 0.001 11843 10338 2 948.491793 475.2544 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 6.83 2411.4 - 1.23E+06 - - - -2.5767 - 1.158 0.107 - 199.5 1 2 0 -0.0024 8 0 0 0 0.00E+00 1.05E+08 - - - 0.273 0.9907 221125_WJC_METTL3_EV_vs_WT_F02.10342.10342.2 0.0403 16-Aug R.LYPGSVYGR[166.11].L "sp|Q14683|SMC1A_HUMAN,tr|G8JLG1|G8JLG1_HUMAN,tr|A0A6Q8PHC3|A0A6Q8PHC3_HUMAN" 3 1020.5268 1.01 11844 10342 2 1020.521849 511.2707 Structural maintenance of chromosomes protein 1A OS=Homo sapiens OX=9606 GN=SMC1A PE=1 SV=2 8.59 2412 - 1.39E+06 - - - -4.8524 - 1.579 0.349 - 253.7 1 2 0 -0.005 9 0 0 0 1.55E+08 1.54E+08 - - - 2.9387 0.9596 221125_WJC_METTL3_EV_vs_WT_F02.10348.10348.2 3.29 22-May -.MSDTLTADVIGR.R "sp|Q15813|TBCE_HUMAN,tr|A0A2R8YFL4|A0A2R8YFL4_HUMAN,tr|A0A2R8Y784|A0A2R8Y784_HUMAN,tr|A0A2R8YF12|A0A2R8YF12_HUMAN,tr|A0A2R8Y597|A0A2R8Y597_HUMAN,tr|A0A2R8YFM3|A0A2R8YFM3_HUMAN,tr|A0A2R8Y5Q8|A0A2R8Y5Q8_HUMAN,tr|A0A2R8Y7E7|A0A2R8Y7E7_HUMAN,tr|A0A2R8Y5H6|A0A2R8Y5H6_HUMAN,tr|A0A2R8Y4P2|A0A2R8Y4P2_HUMAN,tr|A0A2R8Y4V6|A0A2R8Y4V6_HUMAN,tr|A0A2R8Y787|A0A2R8Y787_HUMAN,tr|A0A2R8YER9|A0A2R8YER9_HUMAN,tr|A0A2R8Y809|A0A2R8Y809_HUMAN,tr|A0A2R8Y897|A0A2R8Y897_HUMAN,tr|A0A2R8Y6L2|A0A2R8Y6L2_HUMAN,tr|A0A2R8YHI9|A0A2R8YHI9_HUMAN,tr|A0A2U3TZJ6|A0A2U3TZJ6_HUMAN,tr|A0A2R8YH53|A0A2R8YH53_HUMAN" 19 1277.6286 1.83 11846 10348 2 1277.625913 639.8216 Tubulin-specific chaperone E OS=Homo sapiens OX=9606 GN=TBCE PE=1 SV=1 4.21 2412.7 - 919544 - - - -2.0648 - 0.933 0.213 - 40.2 3 2 0 -0.0026 12 0 0 0 5.00E+07 2.73E+07 - - - 0.2178 0.9993 221125_WJC_METTL3_EV_vs_WT_F02.10352.10352.2 7.37E-05 18-Dec K.VDALLSAQPK[136.11].G sp|Q9NYU2|UGGG1_HUMAN 1 1048.6008 0.06 11848 10352 2 1048.597591 525.3077 UDP-glucose:glycoprotein glucosyltransferase 1 OS=Homo sapiens OX=9606 GN=UGGT1 PE=1 SV=3 5.81 2413.2 - 1.48E+06 - - - -3.0698 - 2.443 0.417 - 619.5 1 2 0 -0.0032 10 0 0 0 3.60E+06 6.25E+07 - - - 4.6132 0.9774 221125_WJC_METTL3_EV_vs_WT_F02.10355.10355.2 9.12E-05 14-Sep R.PGFSIADK[136.11].K "sp|P62913|RL11_HUMAN,tr|Q5VVC8|Q5VVC8_HUMAN" 2 841.4425 1.26 11849 10355 2 841.442905 421.7285 60S ribosomal protein L11 OS=Homo sapiens OX=9606 GN=RPL11 PE=1 SV=2 6.26 2413.6 - 8.79E+06 - - - 0.4587 - 1.881 0.329 - 235.7 1 1 0 0.0004 8 0 0 0 6.59E+08 5.25E+08 - - - 3.3764 0.9866 221125_WJC_METTL3_EV_vs_WT_F02.10358.10358.2 0.909 12-Jun K.TLVDIAK[136.11].S "sp|Q99832|TCPH_HUMAN,sp|Q9H2S1|KCNN2_HUMAN,tr|F8WAM2|F8WAM2_HUMAN,tr|A0A3F2YNY5|A0A3F2YNY5_HUMAN,tr|A0A0J9YW81|A0A0J9YW81_HUMAN,tr|A0A669KBH3|A0A669KBH3_HUMAN" 6 766.468 0.14 11851 10358 2 766.466545 384.2413 T-complex protein 1 subunit eta OS=Homo sapiens OX=9606 GN=CCT7 PE=1 SV=2 5.5 2413.9 - 6.41E+06 - - - -1.9048 - 1.2 0.173 - 144.6 1 2 0 -0.0015 7 0 0 0 7.46E+08 5.37E+09 - - - 0.896 0.9803 221125_WJC_METTL3_EV_vs_WT_F02.10366.10366.2 3.44 12-Jun K.IFGGEIK.T "sp|P07237|PDIA1_HUMAN,tr|A0A7P0TA97|A0A7P0TA97_HUMAN,tr|A0A7P0T8C0|A0A7P0T8C0_HUMAN,tr|H7BZ94|H7BZ94_HUMAN,tr|A0A7P0TA71|A0A7P0TA71_HUMAN,tr|I3L4M2|I3L4M2_HUMAN,tr|A0A7P0T9D6|A0A7P0T9D6_HUMAN,tr|A0A7P0T9K9|A0A7P0T9K9_HUMAN,tr|H0Y3Z3|H0Y3Z3_HUMAN,tr|A0A7P0TA35|A0A7P0TA35_HUMAN,tr|I3L514|I3L514_HUMAN,tr|A0A7P0TB26|A0A7P0TB26_HUMAN,tr|A0A7P0T9U6|A0A7P0T9U6_HUMAN,tr|I3L3P5|I3L3P5_HUMAN,tr|A0A7P0T8X1|A0A7P0T8X1_HUMAN" 15 762.4276 1.24 11856 10366 2 762.427568 382.2211 Protein disulfide-isomerase OS=Homo sapiens OX=9606 GN=P4HB PE=1 SV=3 6 2414.8 - 4.01E+06 - - - -0.0289 - 1.292 0.071 - 87.7 3 2 0 0 7 0 0 0 4.43E+08 3.57E+08 - - - 0.164 0.9989 221125_WJC_METTL3_EV_vs_WT_F02.10367.10367.2 0.0293 16-Sep K.FLSDEENLK.L "sp|Q03393|PTPS_HUMAN,tr|E9PKY8|E9PKY8_HUMAN,tr|E9PJM0|E9PJM0_HUMAN" 3 1093.5292 2.58 11857 10367 2 1093.528667 547.7719 6-pyruvoyl tetrahydrobiopterin synthase OS=Homo sapiens OX=9606 GN=PTS PE=1 SV=1 4.14 2414.9 - 1.12E+06 - - - -0.4463 - 1.4 0.311 - 191.5 1 2 0 -0.0005 9 0 0 0 3.93E+07 1.52E+07 - - - 2.3113 0.9995 221125_WJC_METTL3_EV_vs_WT_F02.10370.10370.2 0.0278 14-Aug R.VMGLVPAK[136.11].G "sp|P49327|FAS_HUMAN,tr|A0A0U1RQF0|A0A0U1RQF0_HUMAN" 2 821.4924 0.85 11858 10370 2 821.492603 411.7535 Fatty acid synthase OS=Homo sapiens OX=9606 GN=FASN PE=1 SV=3 8.72 2415.4 - 2.20E+06 - - - 0.1911 - 1.407 0.407 - 195.8 1 2 0 0.0002 8 0 0 0 7.26E+07 8.57E+07 - - - 3.0769 0.9841 221125_WJC_METTL3_EV_vs_WT_F02.10372.10372.2 1.27 14-Sep K.TPIPTSLR[166.11].K sp|Q6P1L8|RM14_HUMAN 1 893.521 1.87 11859 10372 2 893.518783 447.7678 "39S ribosomal protein L14, mitochondrial OS=Homo sapiens OX=9606 GN=MRPL14 PE=1 SV=1" 9.41 2415.6 - 723233 - - - -2.4666 - 1.466 0.117 - 207.9 1 2 0 -0.0022 8 0 0 0 9.80E+07 5.24E+07 - - - 1.0582 0.9849 221125_WJC_METTL3_EV_vs_WT_F02.10381.10381.2 0.0785 14-Sep R.FLEQGIC[160.03]R[166.11].Y "sp|P42694|HELZ_HUMAN,tr|J3QS41|J3QS41_HUMAN,tr|A0A075B6R3|A0A075B6R3_HUMAN" 3 1031.5098 2.08 11864 10381 2 1031.503051 516.7622 Probable helicase with zinc finger domain OS=Homo sapiens OX=9606 GN=HELZ PE=1 SV=2 5.99 2416.6 - 1.60E+06 - - - -6.5147 - 1.731 0.403 - 316.6 1 2 0 -0.0067 8 0 0 0 9.86E+07 4.75E+07 - - - 3.6703 0.9037 221125_WJC_METTL3_EV_vs_WT_F02.10384.10384.2 0.0932 14-Aug R.FLEQGIC[160.03]R.Y "sp|P42694|HELZ_HUMAN,tr|J3QS41|J3QS41_HUMAN,tr|A0A075B6R3|A0A075B6R3_HUMAN" 3 1021.5015 2.08 11866 10384 2 1021.493697 511.758 Probable helicase with zinc finger domain OS=Homo sapiens OX=9606 GN=HELZ PE=1 SV=2 5.99 2416.9 - 2.72E+06 - - - -7.6397 - 1.48 0.295 - 249 1 2 0 -0.0078 8 0 0 0 9.83E+07 4.74E+07 - - - 2.3998 0.999 221125_WJC_METTL3_EV_vs_WT_F02.10385.10385.2 0.0774 14-Jul R.AVFQESIR[166.11].W "sp|O00139|KIF2A_HUMAN,tr|A0A6Q8PFA6|A0A6Q8PFA6_HUMAN,tr|A0A6Q8PGG1|A0A6Q8PGG1_HUMAN,tr|A0A6Q8PGH7|A0A6Q8PGH7_HUMAN,tr|A0A6Q8PG37|A0A6Q8PG37_HUMAN,tr|A0A6Q8PH57|A0A6Q8PH57_HUMAN" 6 958.5112 1.1 11867 10385 2 958.511388 480.2629 Kinesin-like protein KIF2A OS=Homo sapiens OX=9606 GN=KIF2A PE=1 SV=3 6.05 2416.9 - 3.54E+06 - - - 0.2473 - 1.51 0.282 - 170.3 1 2 0 0.0002 8 0 0 0 8.56E+07 7.80E+07 - - - 2.3667 0.9917 221125_WJC_METTL3_EV_vs_WT_F02.10386.10386.2 0.000283 12-Jul R.C[160.03]PMELVR[166.11].C "sp|P51692|STA5B_HUMAN,tr|C9J4I3|C9J4I3_HUMAN" 2 913.4389 0.49 11868 10386 2 913.440405 457.7267 Signal transducer and activator of transcription 5B OS=Homo sapiens OX=9606 GN=STAT5B PE=1 SV=2 5.99 2417.1 - 1.19E+06 - - - 1.6323 - 1.665 0.071 - 187.6 1 2 0 0.0015 7 0 0 0 1.73E+07 3.56E+07 - - - 1.1803 0.9999 221125_WJC_METTL3_EV_vs_WT_F02.10390.10390.2 5.75E-05 13/20 K.LSAMMGAVAEK[136.11].K "sp|Q86U44|MTA70_HUMAN,tr|F5H6D8|F5H6D8_HUMAN,tr|H0YFV6|H0YFV6_HUMAN,tr|B4DTN4|B4DTN4_HUMAN" 4 1114.5606 0.48 11870 10390 2 1114.560585 558.2876 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 6 2417.6 - 832746 - - - -0.0153 - 2.474 0.444 - 510.8 1 2 0 0 11 0 0 0 4.30E+07 8.90E+07 - - - 4.7709 0.9999 221125_WJC_METTL3_EV_vs_WT_F02.10396.10396.2 0.264 22-Dec K.VLVASATMDTAR.F "sp|O60231|DHX16_HUMAN,tr|A0A140T947|A0A140T947_HUMAN,tr|A0A140T9T4|A0A140T9T4_HUMAN,tr|Q5SQH5|Q5SQH5_HUMAN,tr|A0A140T8Y5|A0A140T8Y5_HUMAN" 5 1233.6387 1.38 11873 10396 2 1233.638844 617.8266 Pre-mRNA-splicing factor ATP-dependent RNA helicase DHX16 OS=Homo sapiens OX=9606 GN=DHX16 PE=1 SV=2 5.81 2418.4 - 643412 - - - 0.0989 - 2.413 0.518 - 525.1 1 2 0 0.0001 12 0 0 0 7.34E+07 5.30E+07 - - - 5.1846 0.9999 221125_WJC_METTL3_EV_vs_WT_F02.10397.10397.2 4.09E-06 22-Dec K.VLVASATMDTAR[166.11].F "sp|O60231|DHX16_HUMAN,tr|A0A140T947|A0A140T947_HUMAN,tr|A0A140T9T4|A0A140T9T4_HUMAN,tr|Q5SQH5|Q5SQH5_HUMAN,tr|A0A140T8Y5|A0A140T8Y5_HUMAN" 5 1243.647 1.38 11874 10397 2 1243.645838 622.8308 Pre-mRNA-splicing factor ATP-dependent RNA helicase DHX16 OS=Homo sapiens OX=9606 GN=DHX16 PE=1 SV=2 5.81 2418.5 - 568217 - - - -0.9279 - 2.219 0.556 - 522.3 1 2 0 -0.0012 12 0 0 0 7.32E+07 5.30E+07 - - - 5.2444 0.9973 221125_WJC_METTL3_EV_vs_WT_F02.10399.10399.2 0.342 14-Aug R.LLDEEISR.V sp|Q96PU8|QKI_HUMAN 1 973.508 2.26 11875 10399 2 973.506109 487.7613 Protein quaking OS=Homo sapiens OX=9606 GN=QKI PE=1 SV=1 4.14 2418.8 - 6.38E+06 - - - -1.9692 - 1.605 0.227 - 152 1 2 0 -0.0019 8 0 0 0 4.41E+09 1.95E+09 - - - 2.1439 0.9553 221125_WJC_METTL3_EV_vs_WT_F02.10407.10407.2 1.13 12-Jun R.SLYLETR[166.11].K "sp|Q9P0U3|SENP1_HUMAN,tr|F8VRZ8|F8VRZ8_HUMAN" 2 890.4737 0.81 11880 10407 2 890.475066 446.2441 Sentrin-specific protease 1 OS=Homo sapiens OX=9606 GN=SENP1 PE=1 SV=2 5.72 2419.6 - 1.51E+06 - - - 1.5318 - 1.095 0.089 - 109.4 1 2 0 0.0014 7 0 0 0 2.19E+07 2.71E+07 - - - -0.0145 0.9413 221125_WJC_METTL3_EV_vs_WT_F02.10413.10413.2 0.0314 16-Aug K.AVLSAEQLR.D "sp|P50454|SERPH_HUMAN,tr|E9PNX1|E9PNX1_HUMAN,tr|E9PIG2|E9PIG2_HUMAN,tr|E9PPV6|E9PPV6_HUMAN,tr|E9PR70|E9PR70_HUMAN,tr|E9PMI5|E9PMI5_HUMAN,tr|E9PLA6|E9PLA6_HUMAN,tr|E9PRS3|E9PRS3_HUMAN,tr|E9PJH8|E9PJH8_HUMAN,tr|E9PK86|E9PK86_HUMAN,tr|E9PQ34|E9PQ34_HUMAN" 11 985.5556 1.43 11883 10413 2 985.559765 493.7851 Serpin H1 OS=Homo sapiens OX=9606 GN=SERPINH1 PE=1 SV=2 6.05 2420.4 - 3.43E+06 - - - 4.1814 - 1.629 0.076 - 194.4 1 2 0 0.0041 9 0 0 0 1.19E+08 8.38E+07 - - - 1.0128 0.9588 221125_WJC_METTL3_EV_vs_WT_F02.10414.10414.2 1.87 12-May R.LMDVMAK.E sp|Q12874|SF3A3_HUMAN 1 806.403 1.26 11884 10414 2 806.403544 404.2088 Splicing factor 3A subunit 3 OS=Homo sapiens OX=9606 GN=SF3A3 PE=1 SV=1 5.84 2420.5 - 1.64E+06 - - - 0.6349 - 1.156 0.073 - 60.4 4 2 0 0.0005 7 0 0 0 2.01E+08 1.59E+08 - - - -0.2296 0.9965 221125_WJC_METTL3_EV_vs_WT_F02.10415.10415.2 0.116 16-Jun R.FVVTAPPAR[166.11].N "sp|Q9UFW8|CGBP1_HUMAN,tr|C9JUJ0|C9JUJ0_HUMAN" 2 966.5526 1.52 11885 10415 2 966.55417 484.2836 CGG triplet repeat-binding protein 1 OS=Homo sapiens OX=9606 GN=CGGBP1 PE=1 SV=2 9.75 2420.6 - 563227 - - - 1.6026 - 1.402 0.263 - 102.8 2 2 0 0.0015 9 0 0 0 1.81E+08 1.19E+08 - - - 1.8261 0.9797 221125_WJC_METTL3_EV_vs_WT_F02.10421.10421.2 0.162 14-Jun K.YLEENVMR.H "sp|Q4VCS5|AMOT_HUMAN,tr|A6NP16|A6NP16_HUMAN,tr|E7ERM3|E7ERM3_HUMAN" 3 1052.4961 1.25 11889 10421 2 1052.493618 527.2553 Angiomotin OS=Homo sapiens OX=9606 GN=AMOT PE=1 SV=1 4.53 2421.3 - 670420 - - - -2.3402 - 1.081 0.209 - 110.1 1 2 0 -0.0025 8 0 0 0 3.22E+07 2.57E+07 - - - 0.8188 0.9997 221125_WJC_METTL3_EV_vs_WT_F02.10422.10422.2 0.00302 14-Aug K.YLEENVMR[166.11].H "sp|Q4VCS5|AMOT_HUMAN,tr|A6NP16|A6NP16_HUMAN,tr|E7ERM3|E7ERM3_HUMAN" 3 1062.5044 1.23 11890 10422 2 1062.503024 532.2595 Angiomotin OS=Homo sapiens OX=9606 GN=AMOT PE=1 SV=1 4.53 2421.4 - 516815 - - - -1.2489 - 1.732 0.419 - 207.4 1 2 0 -0.0013 8 0 0 0 3.22E+07 2.62E+07 - - - 3.7919 0.9984 221125_WJC_METTL3_EV_vs_WT_F02.10424.10424.2 0.0219 16-Jul K.LVQTPLTDR.C "sp|Q14204|DYHC1_HUMAN,tr|A0A7P0T8N2|A0A7P0T8N2_HUMAN,tr|A0A7P0T9C4|A0A7P0T9C4_HUMAN,tr|A0A7P0TBJ7|A0A7P0TBJ7_HUMAN,tr|A0A804HHY6|A0A804HHY6_HUMAN,tr|A0A7P0T9K2|A0A7P0T9K2_HUMAN,tr|A0A7P0TB64|A0A7P0TB64_HUMAN,tr|A0A2R8Y706|A0A2R8Y706_HUMAN,tr|A0A7P0T916|A0A7P0T916_HUMAN,tr|A0A7P0TB75|A0A7P0TB75_HUMAN,tr|A0A7P0T8W5|A0A7P0T8W5_HUMAN,tr|A0A7P0T9S3|A0A7P0T9S3_HUMAN,tr|A0A7P0TAF3|A0A7P0TAF3_HUMAN,tr|A0A7P0T9F1|A0A7P0T9F1_HUMAN,tr|A0A7P0TAW9|A0A7P0TAW9_HUMAN,tr|A0A2R8YGC7|A0A2R8YGC7_HUMAN,tr|A0A7P0TA13|A0A7P0TA13_HUMAN,tr|A0A7P0T934|A0A7P0T934_HUMAN,tr|A0A7P0TAV5|A0A7P0TAV5_HUMAN,tr|A0A7P0T7V5|A0A7P0T7V5_HUMAN,tr|A0A7P0T9R4|A0A7P0T9R4_HUMAN,tr|A0A2R8Y5T0|A0A2R8Y5T0_HUMAN,tr|A0A7P0T990|A0A7P0T990_HUMAN,tr|A0A7P0T942|A0A7P0T942_HUMAN,tr|A0A2R8YFZ7|A0A2R8YFZ7_HUMAN,tr|A0A7P0T825|A0A7P0T825_HUMAN,tr|A0A2R8Y6H2|A0A2R8Y6H2_HUMAN,tr|A0A7P0TAM4|A0A7P0TAM4_HUMAN" 28 1041.5819 1.66 11892 10424 2 1041.581035 521.7982 Cytoplasmic dynein 1 heavy chain 1 OS=Homo sapiens OX=9606 GN=DYNC1H1 PE=1 SV=5 5.84 2421.7 - 297056 - - - -0.7911 - 1.469 0.259 - 163.5 1 2 0 -0.0008 9 0 0 0 1.09E+08 6.55E+07 - - - 2.0663 0.9985 221125_WJC_METTL3_EV_vs_WT_F02.10429.10429.2 0.00757 12-Jul R.FTDYQLR.V "sp|Q86UP3|ZFHX4_HUMAN,sp|Q15911|ZFHX3_HUMAN,tr|E7EVZ1|E7EVZ1_HUMAN" 3 941.4607 2.3 11895 10429 2 941.459278 471.7376 Zinc finger homeobox protein 4 OS=Homo sapiens OX=9606 GN=ZFHX4 PE=1 SV=1 5.84 2422.2 - 2.43E+06 - - - -1.4902 - 1.482 0.283 - 119.3 1 2 0 -0.0014 7 0 0 0 5.41E+07 2.35E+07 - - - 2.3773 0.9965 221125_WJC_METTL3_EV_vs_WT_F02.10432.10432.2 0.605 12-Jul R.LDLQYAK.L "sp|Q15149|PLEC_HUMAN,tr|E9PMV1|E9PMV1_HUMAN,tr|H0YDN1|H0YDN1_HUMAN" 3 849.4596 1.1 11896 10432 2 849.461384 425.7371 Plectin OS=Homo sapiens OX=9606 GN=PLEC PE=1 SV=3 5.83 2422.6 - 1.94E+06 - - - 2.0778 - 1.465 0.245 - 138.5 1 2 0 0.0018 7 0 0 0 5.30E+07 4.84E+07 - - - 2.0599 0.9997 221125_WJC_METTL3_EV_vs_WT_F02.10434.10434.2 0.00469 20-Oct K.ASLENSLEETK.G "sp|P02533|K1C14_HUMAN,sp|P08779|K1C16_HUMAN,tr|K7ENW6|K7ENW6_HUMAN" 3 1219.5932 999 11897 10434 2 1219.593498 610.8039 "Keratin, type I cytoskeletal 14 OS=Homo sapiens OX=9606 GN=KRT14 PE=1 SV=4" 4.25 2422.8 - 910706 - - - 0.2345 - 1.982 0.359 - 201.1 1 2 0 0.0003 11 0 0 0 2.10E+07 0.00E+00 - - - 3.5432 0.9996 221125_WJC_METTL3_EV_vs_WT_F02.10437.10437.2 0.0413 20-Jul R.AVVGYEDGTIR[166.11].L "sp|Q13685|AAMP_HUMAN,tr|C9JG97|C9JG97_HUMAN,tr|C9JEH3|C9JEH3_HUMAN,tr|C9JTS3|C9JTS3_HUMAN" 4 1188.6014 0.98 11900 10437 2 1188.600487 595.308 Angio-associated migratory cell protein OS=Homo sapiens OX=9606 GN=AAMP PE=1 SV=2 4.37 2423.1 - 262236 - - - -0.7866 - 1.477 0.428 - 177.4 1 2 0 -0.0009 11 0 0 0 2.03E+07 2.07E+07 - - - 3.257 0.9943 221125_WJC_METTL3_EV_vs_WT_F02.10441.10441.2 0.605 14-Jun R.AFMQGQLR[166.11].V "sp|O94761|RECQ4_HUMAN,tr|A0A087X072|A0A087X072_HUMAN" 2 959.4886 0.79 11902 10441 2 959.489909 480.7516 ATP-dependent DNA helicase Q4 OS=Homo sapiens OX=9606 GN=RECQL4 PE=1 SV=2 9.79 2423.6 - 436528 - - - 1.3215 - 1.278 0.21 - 127.7 1 2 0 0.0013 8 0 0 0 5.06E+06 6.44E+06 - - - 1.3315 0.9955 221125_WJC_METTL3_EV_vs_WT_F02.10446.10446.2 1.42 12-Jul K.SIEEIVR.R "sp|P39748|FEN1_HUMAN,tr|I3L3E9|I3L3E9_HUMAN" 2 844.4654 0.63 11905 10446 2 844.465722 423.24 Flap endonuclease 1 OS=Homo sapiens OX=9606 GN=FEN1 PE=1 SV=1 4.53 2424.2 - 1.69E+06 - - - 0.3434 - 1.253 0.196 - 182.2 1 2 0 0.0003 7 0 0 0 1.08E+08 1.73E+08 - - - 1.2032 0.9977 221125_WJC_METTL3_EV_vs_WT_F02.10449.10449.2 0.254 12-Jun K.ALIEMEK[136.11].Q "sp|Q15233|NONO_HUMAN,tr|A0A7I2V535|A0A7I2V535_HUMAN,tr|A0A7I2V4N2|A0A7I2V4N2_HUMAN,tr|A0A7I2V4K9|A0A7I2V4K9_HUMAN,tr|A0A7I2V464|A0A7I2V464_HUMAN,tr|A0A7P0MRW0|A0A7P0MRW0_HUMAN,tr|H7C367|H7C367_HUMAN,tr|A0A7I2V4J2|A0A7I2V4J2_HUMAN,tr|A0A7I2V5Y7|A0A7I2V5Y7_HUMAN,tr|C9JYS8|C9JYS8_HUMAN" 10 840.4506 0.67 11906 10449 2 840.450287 421.2326 Non-POU domain-containing octamer-binding protein OS=Homo sapiens OX=9606 GN=NONO PE=1 SV=4 4.53 2424.6 - 2.06E+06 - - - -0.42 - 1.394 0.218 - 127.6 1 2 0 -0.0004 7 0 0 0 4.18E+08 6.25E+08 - - - 1.7036 0.9871 221125_WJC_METTL3_EV_vs_WT_F02.10450.10450.2 1.06 14-May K.ETALLVDR.Y "sp|Q12996|CSTF3_HUMAN,tr|E9PLP8|E9PLP8_HUMAN" 2 915.5025 5.26 11907 10450 2 915.501887 458.7585 Cleavage stimulation factor subunit 3 OS=Homo sapiens OX=9606 GN=CSTF3 PE=1 SV=1 4.37 2424.7 - 896042 - - - -0.7198 - 1.227 0.114 - 85.8 1 2 0 -0.0007 8 0 0 0 8.19E+07 1.56E+07 - - - 0.4998 0.9999 221125_WJC_METTL3_EV_vs_WT_F02.10452.10452.2 3.58E-05 20-Oct R.AVVGYEDGTIR.L "sp|Q13685|AAMP_HUMAN,tr|C9JG97|C9JG97_HUMAN,tr|C9JEH3|C9JEH3_HUMAN,tr|C9JTS3|C9JTS3_HUMAN" 4 1178.5932 0.6 11909 10452 2 1178.593442 590.3039 Angio-associated migratory cell protein OS=Homo sapiens OX=9606 GN=AAMP PE=1 SV=2 4.37 2424.9 - 494452 - - - 0.2461 - 1.995 0.555 - 403.9 1 2 0 0.0003 11 0 0 0 2.09E+07 3.49E+07 - - - 5.0085 0.9669 221125_WJC_METTL3_EV_vs_WT_F02.10455.10455.2 0.324 12-Jun K.DTLMISR.T "sp|P01859|IGHG2_HUMAN,sp|P01860|IGHG3_HUMAN,sp|P01861|IGHG4_HUMAN,sp|P01857|IGHG1_HUMAN,tr|A0A4W9A917|A0A4W9A917_HUMAN,tr|A0A286YES1|A0A286YES1_HUMAN,tr|A0A0A0MS08|A0A0A0MS08_HUMAN,tr|A0A286YFJ8|A0A286YFJ8_HUMAN,tr|A0A0A0MS07|A0A0A0MS07_HUMAN,tr|A0A286YEY4|A0A286YEY4_HUMAN" 10 834.4269 21.58 11910 10455 2 834.426084 418.2207 Immunoglobulin heavy constant gamma 2 OS=Homo sapiens OX=9606 GN=IGHG2 PE=1 SV=2 5.84 2425.3 - 1.89E+06 - - - -1.0235 - 1.333 0.018 - 114.3 2 2 0 -0.0009 7 0 0 0 3.13E+08 1.45E+07 - - - -0.05 0.9988 221125_WJC_METTL3_EV_vs_WT_F02.10456.10456.2 0.0119 16-Aug R.GGDLMAYDR.R "sp|P61978|HNRPK_HUMAN,tr|Q5T6W2|Q5T6W2_HUMAN" 2 996.4335 1.3 11911 10456 2 996.433056 499.224 Heterogeneous nuclear ribonucleoprotein K OS=Homo sapiens OX=9606 GN=HNRNPK PE=1 SV=1 4.21 2425.3 - 1.99E+06 - - - -0.4255 - 1.406 0.295 - 209 1 2 0 -0.0004 9 0 0 0 8.55E+07 6.56E+07 - - - 2.2055 0.9983 221125_WJC_METTL3_EV_vs_WT_F02.10458.10458.2 0.15 12-Jun K.ALIEMEK.Q "sp|Q15233|NONO_HUMAN,tr|A0A7I2V535|A0A7I2V535_HUMAN,tr|A0A7I2V4N2|A0A7I2V4N2_HUMAN,tr|A0A7I2V4K9|A0A7I2V4K9_HUMAN,tr|A0A7I2V464|A0A7I2V464_HUMAN,tr|A0A7P0MRW0|A0A7P0MRW0_HUMAN,tr|H7C367|H7C367_HUMAN,tr|A0A7I2V4J2|A0A7I2V4J2_HUMAN,tr|A0A7I2V5Y7|A0A7I2V5Y7_HUMAN,tr|C9JYS8|C9JYS8_HUMAN" 10 832.4364 0.67 11913 10458 2 832.436991 417.2255 Non-POU domain-containing octamer-binding protein OS=Homo sapiens OX=9606 GN=NONO PE=1 SV=4 4.53 2425.4 - 1.89E+06 - - - 0.6607 - 1.301 0.295 - 133.2 1 2 0 0.0006 7 0 0 0 4.18E+08 6.25E+08 - - - 2.0534 0.9985 221125_WJC_METTL3_EV_vs_WT_F02.10459.10459.2 0.0421 18-Oct R.IGAPGVEEIK.S sp|Q15208|STK38_HUMAN 1 1011.5601 3.61 11914 10459 2 1011.561452 506.7873 Serine\threonine-protein kinase 38 OS=Homo sapiens OX=9606 GN=STK38 PE=1 SV=1 4.53 2425.5 - 1.26E+06 - - - 1.3751 - 1.649 0.272 - 317 1 2 0 0.0014 10 0 0 0 2.26E+09 6.27E+08 - - - 2.4457 0.9997 221125_WJC_METTL3_EV_vs_WT_F02.10460.10460.2 0.00545 16-Jul R.GGDLMAYDR[166.11].R "sp|P61978|HNRPK_HUMAN,tr|Q5T6W2|Q5T6W2_HUMAN" 2 1006.4417 1.3 11915 10460 2 1006.440624 504.2282 Heterogeneous nuclear ribonucleoprotein K OS=Homo sapiens OX=9606 GN=HNRNPK PE=1 SV=1 4.21 2425.6 - 1.06E+06 - - - -1.1188 - 1.733 0.434 - 222.8 1 2 0 -0.0011 9 0 0 0 8.51E+07 6.56E+07 - - - 3.8369 0.975 221125_WJC_METTL3_EV_vs_WT_F02.10467.10467.2 0.138 16-May R.LYIC[160.03]AGC[160.03]GR[166.11].D sp|Q7L3S4|ZN771_HUMAN 1 1078.4927 1.93 11918 10467 2 1078.495357 540.2536 Zinc finger protein 771 OS=Homo sapiens OX=9606 GN=ZNF771 PE=1 SV=1 8.06 2426.5 - 214218 - - - 2.4256 - 0.863 0.289 - 69.5 1 2 0 0.0026 9 0 0 0 2.39E+07 1.24E+07 - - - 0.7485 0.9993 221125_WJC_METTL3_EV_vs_WT_F02.10472.10472.2 0.00144 18-Sep R.IGAPGVEEIK[136.11].S sp|Q15208|STK38_HUMAN 1 1019.5743 3.61 11921 10472 2 1019.57554 510.7944 Serine\threonine-protein kinase 38 OS=Homo sapiens OX=9606 GN=STK38 PE=1 SV=1 4.53 2427 - 899510 - - - 1.2544 - 1.777 0.328 - 223.8 1 2 0 0.0013 10 0 0 0 2.26E+09 6.27E+08 - - - 3.068 0.9891 221125_WJC_METTL3_EV_vs_WT_F02.10474.10474.2 0.0261 16-Sep K.LVQTPLTDR[166.11].C "sp|Q14204|DYHC1_HUMAN,tr|A0A7P0T8N2|A0A7P0T8N2_HUMAN,tr|A0A7P0T9C4|A0A7P0T9C4_HUMAN,tr|A0A7P0TBJ7|A0A7P0TBJ7_HUMAN,tr|A0A804HHY6|A0A804HHY6_HUMAN,tr|A0A7P0T9K2|A0A7P0T9K2_HUMAN,tr|A0A7P0TB64|A0A7P0TB64_HUMAN,tr|A0A2R8Y706|A0A2R8Y706_HUMAN,tr|A0A7P0T916|A0A7P0T916_HUMAN,tr|A0A7P0TB75|A0A7P0TB75_HUMAN,tr|A0A7P0T8W5|A0A7P0T8W5_HUMAN,tr|A0A7P0T9S3|A0A7P0T9S3_HUMAN,tr|A0A7P0TAF3|A0A7P0TAF3_HUMAN,tr|A0A7P0T9F1|A0A7P0T9F1_HUMAN,tr|A0A7P0TAW9|A0A7P0TAW9_HUMAN,tr|A0A2R8YGC7|A0A2R8YGC7_HUMAN,tr|A0A7P0TA13|A0A7P0TA13_HUMAN,tr|A0A7P0T934|A0A7P0T934_HUMAN,tr|A0A7P0TAV5|A0A7P0TAV5_HUMAN,tr|A0A7P0T7V5|A0A7P0T7V5_HUMAN,tr|A0A7P0T9R4|A0A7P0T9R4_HUMAN,tr|A0A2R8Y5T0|A0A2R8Y5T0_HUMAN,tr|A0A7P0T990|A0A7P0T990_HUMAN,tr|A0A7P0T942|A0A7P0T942_HUMAN,tr|A0A2R8YFZ7|A0A2R8YFZ7_HUMAN,tr|A0A7P0T825|A0A7P0T825_HUMAN,tr|A0A2R8Y6H2|A0A2R8Y6H2_HUMAN,tr|A0A7P0TAM4|A0A7P0TAM4_HUMAN" 28 1051.5901 1.59 11923 10474 2 1051.594797 526.8023 Cytoplasmic dynein 1 heavy chain 1 OS=Homo sapiens OX=9606 GN=DYNC1H1 PE=1 SV=5 5.84 2427.2 - 861209 - - - 4.439 - 1.546 0.302 - 286 1 2 0 0.0047 9 0 0 0 1.04E+08 6.55E+07 - - - 2.5305 0.9009 221125_WJC_METTL3_EV_vs_WT_F02.10475.10475.2 3.34 18-Jul K.FSPVATASYR[166.11].L "sp|O15160|RPAC1_HUMAN,tr|A0A2R8YEZ4|A0A2R8YEZ4_HUMAN,tr|A0A2R8Y5D3|A0A2R8Y5D3_HUMAN,tr|A0A2R8YEY5|A0A2R8YEY5_HUMAN" 4 1107.5588 0.22 11924 10475 2 1107.561029 554.7867 DNA-directed RNA polymerases I and III subunit RPAC1 OS=Homo sapiens OX=9606 GN=POLR1C PE=1 SV=1 8.75 2427.3 - 604459 - - - 1.9864 - 1.165 0.021 - 132.4 1 2 0 0.0022 10 0 0 0 1.95E+07 8.71E+07 - - - -0.3783 0.998 221125_WJC_METTL3_EV_vs_WT_F02.10476.10476.2 0.00105 18-Oct K.LGGYETITAR[166.11].R "sp|Q14865|ARI5B_HUMAN,tr|A0A7P0TAD2|A0A7P0TAD2_HUMAN" 2 1089.5694 1.19 11925 10476 2 1089.573077 545.792 AT-rich interactive domain-containing protein 5B OS=Homo sapiens OX=9606 GN=ARID5B PE=1 SV=3 6 2427.5 - 138122 - - - 3.3802 - 1.759 0.389 - 279.7 1 2 0 0.0037 10 0 0 0 1.09E+07 9.18E+06 - - - 3.4894 0.9993 221125_WJC_METTL3_EV_vs_WT_F02.10480.10480.2 0.00062 18-Aug K.VEPATPLAVR[166.11].F sp|Q9H2M9|RBGPR_HUMAN 1 1061.6109 1.42 11926 10480 2 1061.611937 531.8127 Rab3 GTPase-activating protein non-catalytic subunit OS=Homo sapiens OX=9606 GN=RAB3GAP2 PE=1 SV=1 5.97 2428 - 425238 - - - 1.0098 - 1.543 0.366 - 247 1 2 0 0.0011 10 0 0 0 2.56E+07 1.80E+07 - - - 2.9546 0.9775 221125_WJC_METTL3_EV_vs_WT_F02.10482.10482.2 0.046 14-Jul R.IIEPLTSR[166.11].C "sp|P35249|RFC4_HUMAN,tr|C9J8M3|C9J8M3_HUMAN,tr|C9JZI1|C9JZI1_HUMAN" 3 937.5472 2.34 11928 10482 2 937.546083 469.7809 Replication factor C subunit 4 OS=Homo sapiens OX=9606 GN=RFC4 PE=1 SV=2 6 2428.2 - 1.07E+06 - - - -1.1935 - 1.42 0.021 - 130.1 1 2 0 -0.0011 8 0 0 0 6.65E+08 2.84E+08 - - - 0.2533 0.8433 221125_WJC_METTL3_EV_vs_WT_F02.10484.10484.2 8.28 14-Jun R.IIAEALTR[166.11].V "sp|Q969V3|NCLN_HUMAN,tr|K7EMW4|K7EMW4_HUMAN,tr|K7ELZ9|K7ELZ9_HUMAN,tr|K7ENM2|K7ENM2_HUMAN,tr|A0A0C4DGP7|A0A0C4DGP7_HUMAN" 5 895.5366 1.42 11930 10484 2 895.539865 448.7756 Nicalin OS=Homo sapiens OX=9606 GN=NCLN PE=1 SV=2 6 2428.4 - 1.36E+06 - - - 3.6045 - 1.165 0.068 - 77.5 1 2 0 0.0032 8 0 0 0 8.45E+07 5.96E+07 - - - 0.0028 0.9988 221125_WJC_METTL3_EV_vs_WT_F02.10485.10485.2 0.000892 18-Jul K.LGGYETITAR.R "sp|Q14865|ARI5B_HUMAN,tr|A0A7P0TAD2|A0A7P0TAD2_HUMAN" 2 1079.5611 1.19 11931 10485 2 1079.563052 540.7878 AT-rich interactive domain-containing protein 5B OS=Homo sapiens OX=9606 GN=ARID5B PE=1 SV=3 6 2428.5 - 194842 - - - 1.7859 - 1.393 0.392 - 114.3 1 2 0 0.0019 10 0 0 0 1.09E+07 9.18E+06 - - - 2.8609 0.9984 221125_WJC_METTL3_EV_vs_WT_F02.10494.10494.2 0.00754 14-Jul K.EAGVFVPR[166.11].S sp|P53396|ACLY_HUMAN 1 883.4791 0.54 11935 10494 2 883.480209 442.7468 ATP-citrate synthase OS=Homo sapiens OX=9606 GN=ACLY PE=1 SV=3 6.1 2429.6 - 3.37E+06 - - - 1.2304 - 1.421 0.296 - 170.8 1 2 0 0.0011 8 0 0 0 6.73E+07 1.24E+08 - - - 2.2866 0.9994 221125_WJC_METTL3_EV_vs_WT_F02.10506.10506.2 0.000974 18-Jul K.FSPVATASYR.L "sp|O15160|RPAC1_HUMAN,tr|A0A2R8YEZ4|A0A2R8YEZ4_HUMAN,tr|A0A2R8Y5D3|A0A2R8Y5D3_HUMAN,tr|A0A2R8YEY5|A0A2R8YEY5_HUMAN" 4 1097.5506 0.22 11944 10506 2 1097.551872 549.7826 DNA-directed RNA polymerases I and III subunit RPAC1 OS=Homo sapiens OX=9606 GN=POLR1C PE=1 SV=1 8.75 2430.8 - 590454 - - - 1.1963 - 1.432 0.442 - 157.8 1 2 0 0.0013 10 0 0 0 1.95E+07 8.71E+07 - - - 3.3075 0.9928 221125_WJC_METTL3_EV_vs_WT_F02.10507.10507.2 0.0513 18-Jul K.VAVTPPGLAR[166.11].E "sp|P28331|NDUS1_HUMAN,tr|B4DJ81|B4DJ81_HUMAN" 2 989.5897 1.32 11945 10507 2 989.586923 495.8021 "NADH-ubiquinone oxidoreductase 75 kDa subunit, mitochondrial OS=Homo sapiens OX=9606 GN=NDUFS1 PE=1 SV=3" 9.72 2430.9 - 355860 - - - -2.8416 - 1.433 0.247 - 163.7 1 2 0 -0.0028 10 0 0 0 8.88E+07 6.75E+07 - - - 1.8687 0.9814 221125_WJC_METTL3_EV_vs_WT_F02.10511.10511.2 1.23 16-Jul K.VPTSMVLTK[136.11].V sp|Q7Z434|MAVS_HUMAN 1 982.5613 0.97 11946 10511 2 982.56192 492.2879 Mitochondrial antiviral-signaling protein OS=Homo sapiens OX=9606 GN=MAVS PE=1 SV=2 8.72 2431.5 - 1.08E+06 - - - 0.6778 - 1.146 0.117 - 76.2 1 2 0 0.0007 9 0 0 0 3.90E+07 4.00E+07 - - - 0.2992 0.9981 221125_WJC_METTL3_EV_vs_WT_F02.10512.10512.2 0.00963 14-Jul K.IYPSEFGK[136.11].E "sp|Q9H501|ESF1_HUMAN,tr|A0A087WX71|A0A087WX71_HUMAN" 2 947.4844 0.97 11947 10512 2 947.486212 474.7495 ESF1 homolog OS=Homo sapiens OX=9606 GN=ESF1 PE=1 SV=1 6 2431.6 - 769936 - - - 1.9304 - 1.203 0.397 - 128.6 1 2 0 0.0018 8 0 0 0 3.86E+07 3.99E+07 - - - 2.5301 0.9937 221125_WJC_METTL3_EV_vs_WT_F02.10515.10515.2 1.15 14-Jul R.IIQQGLIR.V sp|Q86YP4|P66A_HUMAN 1 939.5866 1.38 11948 10515 2 939.587086 470.8006 Transcriptional repressor p66-alpha OS=Homo sapiens OX=9606 GN=GATAD2A PE=1 SV=1 9.75 2432 - 922151 - - - 0.5694 - 1.431 0.121 - 107.3 1 2 0 0.0005 8 0 0 0 2.43E+08 1.76E+08 - - - 1.0154 0.9822 221125_WJC_METTL3_EV_vs_WT_F02.10518.10518.2 0.592 14-Sep R.IIQQGLIR[166.11].V sp|Q86YP4|P66A_HUMAN 1 949.5948 1.38 11949 10518 2 949.596499 475.8047 Transcriptional repressor p66-alpha OS=Homo sapiens OX=9606 GN=GATAD2A PE=1 SV=1 9.75 2432.4 - 1.35E+06 - - - 1.7671 - 1.513 0.055 - 207.2 1 2 0 0.0017 8 0 0 0 2.43E+08 1.76E+08 - - - 0.6956 0.9989 221125_WJC_METTL3_EV_vs_WT_F02.10525.10525.2 0.00173 16-Aug R.ELYGVGVEK[136.11].L sp|P40938|RFC3_HUMAN 1 1000.5321 2.17 11954 10525 2 1000.53348 501.2733 Replication factor C subunit 3 OS=Homo sapiens OX=9606 GN=RFC3 PE=1 SV=2 4.53 2433.1 - 1.42E+06 - - - 1.4172 - 1.503 0.336 - 207.1 1 2 0 0.0014 9 0 0 0 1.44E+08 6.64E+07 - - - 2.7011 0.9967 221125_WJC_METTL3_EV_vs_WT_F02.10528.10528.2 0.15 12-Jul K.VMNLISK.L "sp|P50502|F10A1_HUMAN,sp|Q8NFI4|F10A5_HUMAN" 2 803.4575 1.11 11955 10528 2 803.457942 402.736 Hsc70-interacting protein OS=Homo sapiens OX=9606 GN=ST13 PE=1 SV=2 8.72 2433.5 - 4.95E+06 - - - 0.5377 - 1.45 0.171 - 159.2 1 2 0 0.0004 7 0 0 0 1.45E+08 1.30E+08 - - - 1.4812 0.9989 221125_WJC_METTL3_EV_vs_WT_F02.10530.10530.2 0.0125 16-Aug R.LLPQVEAAR[166.11].K "sp|Q86UT8|CATAC_HUMAN,tr|E9PJ16|E9PJ16_HUMAN,tr|E9PPT8|E9PPT8_HUMAN" 3 1005.5847 1.8 11957 10530 2 1005.584768 503.7996 Centrosomal AT-AC splicing factor OS=Homo sapiens OX=9606 GN=CENATAC PE=1 SV=1 6 2433.7 - 671880 - - - 0.1173 - 1.459 0.295 - 208.3 1 2 0 0.0001 9 0 0 0 4.71E+07 2.62E+07 - - - 2.3127 0.9912 221125_WJC_METTL3_EV_vs_WT_F02.10533.10533.2 0.0783 12-Jun K.IVGLQYK[136.11].K "sp|P11388|TOP2A_HUMAN,sp|Q02880|TOP2B_HUMAN,tr|E9PCY5|E9PCY5_HUMAN" 3 827.4996 0.93 11959 10533 2 827.500078 414.7571 DNA topoisomerase 2-alpha OS=Homo sapiens OX=9606 GN=TOP2A PE=1 SV=3 8.59 2434.1 - 3.54E+06 - - - 0.5293 - 1.282 0.128 - 93.2 1 2 0 0.0004 7 0 0 0 1.16E+08 1.25E+08 - - - 0.7734 0.9163 221125_WJC_METTL3_EV_vs_WT_F02.10535.10535.2 1.82 12-May K.IVGLQYK.K "sp|P11388|TOP2A_HUMAN,sp|Q02880|TOP2B_HUMAN,tr|E9PCY5|E9PCY5_HUMAN" 3 819.4854 0.91 11961 10535 2 819.485563 410.75 DNA topoisomerase 2-alpha OS=Homo sapiens OX=9606 GN=TOP2A PE=1 SV=3 8.59 2434.2 - 3.63E+06 - - - 0.1501 - 0.999 0.055 - 53.4 3 2 0 0.0001 7 0 0 0 1.15E+08 1.26E+08 - - - -0.7691 0.9961 221125_WJC_METTL3_EV_vs_WT_F02.10536.10536.2 0.0952 12-Jul K.VMNLISK[136.11].L "sp|P50502|F10A1_HUMAN,sp|Q8NFI4|F10A5_HUMAN" 2 811.4717 1.15 11962 10536 2 811.472491 406.7431 Hsc70-interacting protein OS=Homo sapiens OX=9606 GN=ST13 PE=1 SV=2 8.72 2434.3 - 3.53E+06 - - - 0.9624 - 1.459 0.168 - 107 1 2 0 0.0008 7 0 0 0 1.44E+08 1.26E+08 - - - 1.4785 0.999 221125_WJC_METTL3_EV_vs_WT_F02.10555.10555.2 0.0141 18-Sep K.LLAAEQTVVR.D sp|O95613|PCNT_HUMAN 1 1098.6397 0.44 11972 10555 2 1098.638181 550.3271 Pericentrin OS=Homo sapiens OX=9606 GN=PCNT PE=1 SV=4 6 2436.7 - 552207 - - - -1.3899 - 1.727 0.291 - 246.5 1 2 0 -0.0015 10 0 0 0 1.01E+07 2.29E+07 - - - 2.715 0.9966 221125_WJC_METTL3_EV_vs_WT_F02.10563.10563.2 0.0356 12-Jul R.FFSGYGR[166.11].L "sp|Q13247|SRSF6_HUMAN,tr|A0A590UK80|A0A590UK80_HUMAN,tr|A0A590UJK4|A0A590UJK4_HUMAN,tr|A0A590UJP7|A0A590UJP7_HUMAN,tr|A0A590UK01|A0A590UK01_HUMAN" 5 842.3951 1.08 11975 10563 2 842.395116 422.2048 Serine\arginine-rich splicing factor 6 OS=Homo sapiens OX=9606 GN=SRSF6 PE=1 SV=2 8.75 2437.7 - 3.74E+06 - - - 0.0689 - 1.178 0.246 - 122.2 1 2 0 0.0001 7 0 0 0 1.49E+08 1.38E+08 - - - 1.377 0.9945 221125_WJC_METTL3_EV_vs_WT_F02.10564.10564.2 0.0952 12-Jul R.FFSGYGR.L "sp|Q13247|SRSF6_HUMAN,tr|A0A590UK80|A0A590UK80_HUMAN,tr|A0A590UJK4|A0A590UJK4_HUMAN,tr|A0A590UJP7|A0A590UJP7_HUMAN,tr|A0A590UK01|A0A590UK01_HUMAN" 5 832.3868 1.08 11976 10564 2 832.386671 417.2007 Serine\arginine-rich splicing factor 6 OS=Homo sapiens OX=9606 GN=SRSF6 PE=1 SV=2 8.75 2437.7 - 2.56E+06 - - - -0.1406 - 1.244 0.175 - 129.8 1 2 0 -0.0001 7 0 0 0 1.49E+08 1.38E+08 - - - 1.0253 0.9987 221125_WJC_METTL3_EV_vs_WT_F02.10568.10568.2 0.00457 12-Jul R.FLEVDER.N "sp|Q92696|PGTA_HUMAN,tr|H0YLH3|H0YLH3_HUMAN" 2 906.4447 0.98 11978 10568 2 906.442945 454.2296 Geranylgeranyl transferase type-2 subunit alpha OS=Homo sapiens OX=9606 GN=RABGGTA PE=1 SV=2 4.14 2438.2 - 892959 - - - -1.9328 - 1.408 0.365 - 173.1 1 2 0 -0.0018 7 0 0 0 4.72E+07 4.83E+07 - - - 2.8205 0.9994 221125_WJC_METTL3_EV_vs_WT_F02.10573.10573.2 0.0124 16-Oct R.LTELETAVR.C "sp|Q13561|DCTN2_HUMAN,tr|H0YI98|H0YI98_HUMAN,tr|A8K8J9|A8K8J9_HUMAN,tr|A0A7I2V5R4|A0A7I2V5R4_HUMAN,tr|F8W1I6|F8W1I6_HUMAN,tr|A0A7I2V390|A0A7I2V390_HUMAN,tr|A0A7I2V4Y9|A0A7I2V4Y9_HUMAN,tr|F8VRV7|F8VRV7_HUMAN,tr|F8VW18|F8VW18_HUMAN" 9 1030.5659 3.16 11981 10573 2 1030.565387 516.2902 Dynactin subunit 2 OS=Homo sapiens OX=9606 GN=DCTN2 PE=1 SV=4 4.53 2438.9 - 3.81E+06 - - - -0.4735 - 2.086 0.227 - 428.5 1 2 0 -0.0005 9 0 0 0 4.08E+08 1.29E+08 - - - 2.8446 0.9995 221125_WJC_METTL3_EV_vs_WT_F02.10579.10579.2 0.0696 16-Sep R.LTELETAVR[166.11].C "sp|Q13561|DCTN2_HUMAN,tr|H0YI98|H0YI98_HUMAN,tr|A8K8J9|A8K8J9_HUMAN,tr|A0A7I2V5R4|A0A7I2V5R4_HUMAN,tr|F8W1I6|F8W1I6_HUMAN,tr|A0A7I2V390|A0A7I2V390_HUMAN,tr|A0A7I2V4Y9|A0A7I2V4Y9_HUMAN,tr|F8VRV7|F8VRV7_HUMAN,tr|F8VW18|F8VW18_HUMAN" 9 1040.5741 3 11985 10579 2 1040.573285 521.2943 Dynactin subunit 2 OS=Homo sapiens OX=9606 GN=DCTN2 PE=1 SV=4 4.53 2439.6 - 2.41E+06 - - - -0.8265 - 2.084 0.282 - 303.4 1 2 0 -0.0009 9 0 0 0 4.36E+08 1.45E+08 - - - 3.2479 0.9994 221125_WJC_METTL3_EV_vs_WT_F02.10580.10580.2 0.162 18-Jul K.VAVTPPGLAR.E "sp|P28331|NDUS1_HUMAN,tr|B4DJ81|B4DJ81_HUMAN" 2 979.5815 1.26 11986 10580 2 979.58132 490.798 "NADH-ubiquinone oxidoreductase 75 kDa subunit, mitochondrial OS=Homo sapiens OX=9606 GN=NDUFS1 PE=1 SV=3" 9.72 2439.6 - 1.06E+06 - - - -0.148 - 1.625 0.332 - 184.5 1 2 0 -0.0001 10 0 0 0 8.44E+07 6.71E+07 - - - 2.8483 0.998 221125_WJC_METTL3_EV_vs_WT_F02.10581.10581.2 0.441 14-Jul K.SVFEEEVR[166.11].E sp|Q03252|LMNB2_HUMAN 1 1003.485 1.36 11987 10581 2 1003.485321 502.7498 Lamin-B2 OS=Homo sapiens OX=9606 GN=LMNB2 PE=1 SV=4 4.25 2439.7 - 863112 - - - 0.3249 - 1.391 0.242 - 189.3 1 2 0 0.0003 8 0 0 0 6.04E+07 4.42E+07 - - - 1.8236 0.9929 221125_WJC_METTL3_EV_vs_WT_F02.10582.10582.2 0.422 20-Sep K.LIASVAGSVER[166.11].V "sp|Q13868|EXOS2_HUMAN,tr|A3KFL1|A3KFL1_HUMAN,tr|A3KFL2|A3KFL2_HUMAN,tr|A3KFL5|A3KFL5_HUMAN" 4 1110.6272 1.24 11988 10582 2 1110.626374 556.3209 Exosome complex component RRP4 OS=Homo sapiens OX=9606 GN=EXOSC2 PE=1 SV=2 6 2439.8 - 337480 - - - -0.7824 - 1.529 0.099 - 179.8 1 2 0 -0.0009 11 0 0 0 1.07E+08 8.62E+07 - - - 0.9206 0.8188 221125_WJC_METTL3_EV_vs_WT_F02.10592.10592.2 0.277 12-Jun L.VLPPNWK[136.11].T "sp|Q9BYW2|SETD2_HUMAN,sp|P62277|RS13_HUMAN" 2 860.5 1.02 11994 10592 2 860.500131 431.2573 Histone-lysine N-methyltransferase SETD2 OS=Homo sapiens OX=9606 GN=SETD2 PE=1 SV=3 8.72 2441.1 - 3.57E+06 - - - 0.1825 - 1.127 0.26 - 151.1 1 1 0 0.0002 7 0 0 0 2.19E+08 2.15E+08 - - - 1.3401 0.9966 221125_WJC_METTL3_EV_vs_WT_F02.10594.10594.2 0.00832 20-Aug K.LIASVAGSVER.V "sp|Q13868|EXOS2_HUMAN,tr|A3KFL1|A3KFL1_HUMAN,tr|A3KFL2|A3KFL2_HUMAN,tr|A3KFL5|A3KFL5_HUMAN" 4 1100.619 1.24 11996 10594 2 1100.618412 551.3168 Exosome complex component RRP4 OS=Homo sapiens OX=9606 GN=EXOSC2 PE=1 SV=2 6 2441.3 - 651952 - - - -0.5097 - 1.639 0.14 - 191.9 1 2 0 -0.0006 11 0 0 0 1.07E+08 8.59E+07 - - - 1.4115 0.828 221125_WJC_METTL3_EV_vs_WT_F02.10598.10598.2 0.585 12-May K.YVHYEID.A "sp|Q86U44|MTA70_HUMAN,tr|H0YFV6|H0YFV6_HUMAN" 2 937.4181 - 11998 10598 2 937.41749 469.7164 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 4.64 2441.8 - 4.74E+06 - - - -0.7019 - 0.973 0.335 - 85.9 1 1 0 -0.0007 7 0 0 0 - - - - - 1.4284 0.9771 221125_WJC_METTL3_EV_vs_WT_F02.10600.10600.2 0.772 12-Jun R.VLYSLAK.K "sp|P55265|DSRAD_HUMAN,tr|A0A3B3IRQ9|A0A3B3IRQ9_HUMAN,tr|A0A3B3ISU1|A0A3B3ISU1_HUMAN,tr|A0A7P0Z4K3|A0A7P0Z4K3_HUMAN,tr|A0A3B3ISX1|A0A3B3ISX1_HUMAN" 5 792.4745 1.59 12000 10600 2 792.473653 397.2445 Double-stranded RNA-specific adenosine deaminase OS=Homo sapiens OX=9606 GN=ADAR PE=1 SV=4 8.56 2442 - 1.30E+06 - - - -1.1205 - 0.997 0.161 - 107.2 1 2 0 -0.0009 7 0 0 0 6.08E+07 3.83E+07 - - - 0.2203 0.9975 221125_WJC_METTL3_EV_vs_WT_F02.10603.10603.2 0.208 16-Aug K.ATVTAMIAR[166.11].E "sp|O95793|STAU1_HUMAN,tr|Q5JW30|Q5JW30_HUMAN" 2 942.5196 1.92 12003 10603 2 942.517964 472.2671 Double-stranded RNA-binding protein Staufen homolog 1 OS=Homo sapiens OX=9606 GN=STAU1 PE=1 SV=2 9.79 2442.3 - 1.55E+06 - - - -1.7432 - 1.538 0.245 - 187.3 1 2 0 -0.0016 9 0 0 0 4.56E+08 2.37E+08 - - - 2.0955 0.9235 221125_WJC_METTL3_EV_vs_WT_F02.10608.10608.2 0.194 14-Jun R.LGFTDVNK.L "sp|Q92544|TM9S4_HUMAN,tr|A0A0C4DFM1|A0A0C4DFM1_HUMAN" 2 892.4654 0.53 12005 10608 2 892.460368 447.24 Transmembrane 9 superfamily member 4 OS=Homo sapiens OX=9606 GN=TM9SF4 PE=1 SV=2 5.84 2443 - 2.03E+06 - - - -5.6742 - 1.254 0.25 - 73.9 1 2 0 -0.0051 8 0 0 0 6.25E+07 1.19E+08 - - - 1.5685 0.9992 221125_WJC_METTL3_EV_vs_WT_F02.10610.10610.2 0.000177 22-Nov R.AQVQEFC[160.03]DYGTK[136.11].E "sp|Q86U44|MTA70_HUMAN,tr|H0YFV6|H0YFV6_HUMAN" 2 1452.6435 0.001 12006 10610 2 1452.637686 727.329 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 4.37 2443.2 - 424994 - - - -3.9886 - 2.435 0.579 - 359.9 1 2 0 -0.0058 12 0 0 0 0.00E+00 2.04E+08 - - - 5.6573 0.9868 221125_WJC_METTL3_EV_vs_WT_F02.10613.10613.2 0.011 14-Jul R.LVPSAFEK.Q "sp|Q9Y5J3|HEY1_HUMAN,tr|E5RHK6|E5RHK6_HUMAN,tr|A0A6I8PRS3|A0A6I8PRS3_HUMAN,tr|A0A6I8PRC2|A0A6I8PRC2_HUMAN,tr|A0A6I8PIY0|A0A6I8PIY0_HUMAN" 5 889.4909 1.26 12007 10613 2 889.487896 445.7527 Hairy\enhancer-of-split related with YRPW motif protein 1 OS=Homo sapiens OX=9606 GN=HEY1 PE=1 SV=1 6 2443.6 - 2.00E+06 - - - -3.3986 - 1.31 0.251 - 184.7 1 2 0 -0.003 8 0 0 0 1.78E+08 1.41E+08 - - - 1.7083 0.994 221125_WJC_METTL3_EV_vs_WT_F02.10618.10618.2 1.26 12-Jun K.EGIVALR[166.11].R sp|P40227|TCPZ_HUMAN 1 766.4577 0.03 12009 10618 2 766.456471 384.2361 T-complex protein 1 subunit zeta OS=Homo sapiens OX=9606 GN=CCT6A PE=1 SV=3 6.1 2444.2 - 8.76E+07 - - - -1.5487 - 1.428 0.173 - 207 2 2 0 -0.0012 7 0 0 0 8.86E+07 2.74E+09 - - - 1.3128 0.9962 221125_WJC_METTL3_EV_vs_WT_F02.10621.10621.2 0.405 12-Jul K.TAWLDGK[136.11].H "sp|P23284|PPIB_HUMAN,tr|A0A7P0Z497|A0A7P0Z497_HUMAN,tr|A0A7P0TB45|A0A7P0TB45_HUMAN" 3 797.4163 0.46 12011 10621 2 797.415945 399.7154 Peptidyl-prolyl cis-trans isomerase B OS=Homo sapiens OX=9606 GN=PPIB PE=1 SV=2 5.5 2444.5 - 1.57E+06 - - - -0.4502 - 1.334 0.185 - 226.5 1 2 0 -0.0004 7 0 0 0 7.14E+07 1.55E+08 - - - 1.3204 0.9964 221125_WJC_METTL3_EV_vs_WT_F02.10625.10625.2 0.12 12-Jul K.SILAEYK[136.11].L sp|Q9Y295|DRG1_HUMAN 1 830.4629 0.31 12013 10625 2 830.461527 416.2387 Developmentally-regulated GTP-binding protein 1 OS=Homo sapiens OX=9606 GN=DRG1 PE=1 SV=1 5.72 2445 - 2.43E+06 - - - -1.6774 - 1.232 0.278 - 183.5 1 2 0 -0.0014 7 0 0 0 4.77E+07 1.53E+08 - - - 1.755 0.9917 221125_WJC_METTL3_EV_vs_WT_F02.10627.10627.2 0.161 14-Jun R.VVSLSEYR[166.11].Q "sp|O00567|NOP56_HUMAN,tr|A0A494C128|A0A494C128_HUMAN,tr|H0YDU4|H0YDU4_HUMAN,tr|H0Y653|H0Y653_HUMAN" 4 961.5108 1.08 12014 10627 2 961.508411 481.7627 Nucleolar protein 56 OS=Homo sapiens OX=9606 GN=NOP56 PE=1 SV=4 5.97 2445.2 - 1.68E+06 - - - -2.5013 - 1.673 0.149 - 101.2 2 2 0 -0.0024 8 0 0 0 1.39E+08 1.28E+08 - - - 1.5584 0.9909 221125_WJC_METTL3_EV_vs_WT_F02.10634.10634.2 0.000601 14-Jul R.VVSLSEYR.Q "sp|O00567|NOP56_HUMAN,tr|A0A494C128|A0A494C128_HUMAN,tr|H0YDU4|H0YDU4_HUMAN,tr|H0Y653|H0Y653_HUMAN" 4 951.5025 1.07 12017 10634 2 951.505234 476.7585 Nucleolar protein 56 OS=Homo sapiens OX=9606 GN=NOP56 PE=1 SV=4 5.97 2446.1 - 1.61E+06 - - - 2.825 - 1.385 0.227 - 170.9 1 2 0 0.0027 8 0 0 0 1.37E+08 1.28E+08 - - - 1.6991 0.9881 221125_WJC_METTL3_EV_vs_WT_F02.10635.10635.2 0.018 14-Jul R.VTMPVAYK.E "sp|P22735|TGM1_HUMAN,tr|H0YMQ8|H0YMQ8_HUMAN" 2 907.4837 999 12018 10635 2 907.480116 454.7491 Protein-glutamine gamma-glutamyltransferase K OS=Homo sapiens OX=9606 GN=TGM1 PE=1 SV=4 8.56 2446.3 - 971632 - - - -3.9769 - 1.514 0.25 - 155.9 1 2 0 -0.0036 8 0 0 0 9.41E+07 0.00E+00 - - - 2.1372 0.9993 221125_WJC_METTL3_EV_vs_WT_F02.10638.10638.2 0.000686 16-Aug R.FLGTTC[160.03]YDR[166.11].S sp|O43172|PRP4_HUMAN 1 1141.5102 2.82 12019 10638 2 1141.507397 571.7624 U4\U6 small nuclear ribonucleoprotein Prp4 OS=Homo sapiens OX=9606 GN=PRPF4 PE=1 SV=2 5.83 2446.7 - 955216 - - - -2.4249 - 1.614 0.466 - 109.4 1 2 0 -0.0028 9 0 0 0 3.23E+08 1.14E+08 - - - 3.867 0.9878 221125_WJC_METTL3_EV_vs_WT_F02.10640.10640.2 0.448 12-Jul K.TAWLDGK.H "sp|P23284|PPIB_HUMAN,tr|A0A7P0Z497|A0A7P0Z497_HUMAN,tr|A0A7P0TB45|A0A7P0TB45_HUMAN" 3 789.4021 0.46 12021 10640 2 789.400258 395.7083 Peptidyl-prolyl cis-trans isomerase B OS=Homo sapiens OX=9606 GN=PPIB PE=1 SV=2 5.5 2446.8 - 1.69E+06 - - - -2.3385 - 1.23 0.201 - 198.3 1 2 0 -0.0018 7 0 0 0 7.14E+07 1.55E+08 - - - 1.1809 0.9982 221125_WJC_METTL3_EV_vs_WT_F02.10653.10653.2 0.0564 14-Jul R.MLAEDELR[166.11].D "sp|P84077|ARF1_HUMAN,sp|P61204|ARF3_HUMAN,tr|F5H423|F5H423_HUMAN" 3 985.4778 1.11 12027 10653 2 985.474427 493.7462 ADP-ribosylation factor 1 OS=Homo sapiens OX=9606 GN=ARF1 PE=1 SV=2 4.14 2448.5 - 2.88E+06 - - - -3.4247 - 1.623 0.415 - 146.5 1 2 0 -0.0034 8 0 0 0 7.70E+08 6.95E+08 - - - 3.5657 0.999 221125_WJC_METTL3_EV_vs_WT_F02.10658.10658.2 0.00894 12-Jul K.NFAELAR[166.11].R sp|Q9Y3C6|PPIL1_HUMAN 1 829.4322 1.32 12028 10658 2 829.432975 415.7234 Peptidyl-prolyl cis-trans isomerase-like 1 OS=Homo sapiens OX=9606 GN=PPIL1 PE=1 SV=1 6 2449.2 - 4.70E+06 - - - 0.9681 - 1.335 0.36 - 216.1 1 2 0 0.0008 7 0 0 0 1.63E+08 1.24E+08 - - - 2.6152 0.9993 221125_WJC_METTL3_EV_vs_WT_F02.10663.10663.2 0.00245 14-Oct K.SVPLALQR.V "sp|Q93009|UBP7_HUMAN,tr|A0A669KBL1|A0A669KBL1_HUMAN,tr|F5H2X1|F5H2X1_HUMAN,tr|H3BND8|H3BND8_HUMAN" 4 882.5287 3.43 12029 10663 2 882.52827 442.2716 Ubiquitin carboxyl-terminal hydrolase 7 OS=Homo sapiens OX=9606 GN=USP7 PE=1 SV=2 9.47 2449.8 - 2.28E+06 - - - -0.4884 - 1.411 0.353 - 428.3 1 2 0 -0.0004 8 0 0 0 2.02E+08 5.87E+07 - - - 2.6865 0.9902 221125_WJC_METTL3_EV_vs_WT_F02.10665.10665.2 0.0011 14-Sep K.MLVIEQC[160.03]K[136.11].N "sp|P48643|TCPE_HUMAN,tr|E9PCA1|E9PCA1_HUMAN,tr|B7ZAR1|B7ZAR1_HUMAN,tr|E7ENZ3|E7ENZ3_HUMAN" 4 1027.5286 0.58 12030 10665 2 1027.534597 514.7716 T-complex protein 1 subunit epsilon OS=Homo sapiens OX=9606 GN=CCT5 PE=1 SV=1 5.75 2450 - 1.90E+06 - - - 5.8616 - 1.793 0.388 - 321.3 1 2 0 0.006 8 0 0 0 5.31E+08 9.09E+08 - - - 3.6659 0.9987 221125_WJC_METTL3_EV_vs_WT_F02.10667.10667.2 0.00217 14-Sep K.IPAMTIAK[136.11].N "sp|P10809|CH60_HUMAN,tr|A0A7I2V2X6|A0A7I2V2X6_HUMAN,tr|A0A7I2YQK6|A0A7I2YQK6_HUMAN,tr|A0A7I2V599|A0A7I2V599_HUMAN" 4 851.503 1.2 12032 10667 2 851.500487 426.7588 "60 kDa heat shock protein, mitochondrial OS=Homo sapiens OX=9606 GN=HSPD1 PE=1 SV=2" 8.75 2450.2 - 2.02E+07 - - - -2.963 - 1.665 0.408 - 242.1 1 2 0 -0.0025 8 0 0 0 3.80E+10 3.16E+10 - - - 3.5913 0.9997 221125_WJC_METTL3_EV_vs_WT_F02.10677.10677.2 0.00339 18-Oct R.ILIENGVAER[166.11].Q "sp|Q9H0A0|NAT10_HUMAN,tr|E9PMU0|E9PMU0_HUMAN,tr|E9PJN6|E9PJN6_HUMAN" 3 1122.6272 0.36 12038 10677 2 1122.626778 562.3209 RNA cytidine acetyltransferase OS=Homo sapiens OX=9606 GN=NAT10 PE=1 SV=2 4.53 2451.4 - 1.51E+06 - - - -0.4142 - 1.917 0.358 - 267.5 1 2 0 -0.0005 10 0 0 0 5.61E+07 1.55E+08 - - - 3.5015 0.9858 221125_WJC_METTL3_EV_vs_WT_F02.10685.10685.2 0.977 14-Sep K.LLALQEEK[136.11].H "sp|Q13227|GPS2_HUMAN,tr|I3L3Y9|I3L3Y9_HUMAN,tr|I3L4X7|I3L4X7_HUMAN" 3 950.5528 1.82 12040 10685 2 950.549494 476.2837 G protein pathway suppressor 2 OS=Homo sapiens OX=9606 GN=GPS2 PE=1 SV=3 4.53 2452.5 - 3.19E+06 - - - -3.4748 - 1.645 0.156 - 213.3 1 2 0 -0.0033 8 0 0 0 1.62E+08 8.88E+07 - - - 1.6933 0.9806 221125_WJC_METTL3_EV_vs_WT_F02.10689.10689.2 0.701 18-Oct R.ILIENGVAER.Q "sp|Q9H0A0|NAT10_HUMAN,tr|E9PMU0|E9PMU0_HUMAN,tr|E9PJN6|E9PJN6_HUMAN" 3 1112.619 0.36 12041 10689 2 1112.61511 557.3168 RNA cytidine acetyltransferase OS=Homo sapiens OX=9606 GN=NAT10 PE=1 SV=2 4.53 2453.1 - 1.78E+06 - - - -3.472 - 1.653 0.136 - 294.2 1 2 0 -0.0039 10 0 0 0 5.61E+07 1.55E+08 - - - 1.4472 0.987 221125_WJC_METTL3_EV_vs_WT_F02.10698.10698.2 0.0412 14-Aug K.MLVIEQC[160.03]K.N "sp|P48643|TCPE_HUMAN,tr|E9PCA1|E9PCA1_HUMAN,tr|B7ZAR1|B7ZAR1_HUMAN,tr|E7ENZ3|E7ENZ3_HUMAN" 4 1019.5144 0.58 12044 10698 2 1019.509902 510.7645 T-complex protein 1 subunit epsilon OS=Homo sapiens OX=9606 GN=CCT5 PE=1 SV=1 5.75 2454.3 - 8.45E+06 - - - -4.3864 - 1.674 0.233 - 257.4 1 2 0 -0.0045 8 0 0 0 5.31E+08 9.09E+08 - - - 2.3144 0.9968 221125_WJC_METTL3_EV_vs_WT_F02.10699.10699.2 1.51 12-Jul R.NLGALYR.R "sp|Q9NSK0|KLC4_HUMAN,sp|Q07866|KLC1_HUMAN,tr|G3V5R9|G3V5R9_HUMAN,tr|H0YJL0|H0YJL0_HUMAN,tr|G3V3H3|G3V3H3_HUMAN,tr|F8W6L3|F8W6L3_HUMAN,tr|E7EVH7|E7EVH7_HUMAN,tr|H0YJT3|H0YJT3_HUMAN,tr|G3V2E7|G3V2E7_HUMAN,tr|H0YJU9|H0YJU9_HUMAN,tr|G5E9S8|G5E9S8_HUMAN,tr|H0YG16|H0YG16_HUMAN" 12 805.4446 0.72 12045 10699 2 805.443499 403.7296 Kinesin light chain 4 OS=Homo sapiens OX=9606 GN=KLC4 PE=1 SV=3 8.75 2454.5 - 1.87E+06 - - - -1.4129 - 1.433 0.211 - 201.4 1 2 0 -0.0011 7 0 0 0 4.39E+07 6.10E+07 - - - 1.739 0.9988 221125_WJC_METTL3_EV_vs_WT_F02.10702.10702.2 0.00582 14-Aug K.IPAMTIAK.N "sp|P10809|CH60_HUMAN,tr|A0A7I2V2X6|A0A7I2V2X6_HUMAN,tr|A0A7I2YQK6|A0A7I2YQK6_HUMAN,tr|A0A7I2V599|A0A7I2V599_HUMAN" 4 843.4888 1.2 12046 10702 2 843.487256 422.7517 "60 kDa heat shock protein, mitochondrial OS=Homo sapiens OX=9606 GN=HSPD1 PE=1 SV=2" 8.75 2454.9 - 6.04E+08 - - - -1.8423 - 1.53 0.334 - 177.6 1 2 0 -0.0016 8 0 0 0 3.80E+10 3.17E+10 - - - 2.79 0.9997 221125_WJC_METTL3_EV_vs_WT_F02.10719.10719.2 0.00553 16-Oct K.LSDGVAVLK[136.11].V "sp|P10809|CH60_HUMAN,tr|A0A7I2V2X6|A0A7I2V2X6_HUMAN,tr|A0A7I2YQK6|A0A7I2YQK6_HUMAN,tr|A0A7I2V599|A0A7I2V599_HUMAN" 4 908.5422 1.23 12049 10719 2 908.5419 455.2784 "60 kDa heat shock protein, mitochondrial OS=Homo sapiens OX=9606 GN=HSPD1 PE=1 SV=2" 5.84 2457.4 - 6.55E+06 - - - -0.3665 - 2.107 0.324 - 198.8 1 2 0 -0.0003 9 0 0 0 6.40E+10 5.22E+10 - - - 3.5901 0.8567 221125_WJC_METTL3_EV_vs_WT_F02.10731.10731.2 0.0667 12-Aug R.LGSFPVR.G sp|Q8WUM0|NU133_HUMAN 1 774.4388 3.88 12053 10731 2 774.433277 388.2267 Nuclear pore complex protein Nup133 OS=Homo sapiens OX=9606 GN=NUP133 PE=1 SV=2 9.75 2459.1 - 1.35E+06 - - - -7.1626 - 1.703 0.145 - 181.6 1 2 0 -0.0055 7 0 0 0 1.45E+09 3.74E+08 - - - 1.7971 0.993 221125_WJC_METTL3_EV_vs_WT_F02.10733.10733.2 0.0816 16-Aug K.LSDGVAVLK.V "sp|P10809|CH60_HUMAN,tr|A0A7I2V2X6|A0A7I2V2X6_HUMAN,tr|A0A7I2YQK6|A0A7I2YQK6_HUMAN,tr|A0A7I2V599|A0A7I2V599_HUMAN" 4 900.528 1.23 12054 10733 2 900.524936 451.2713 "60 kDa heat shock protein, mitochondrial OS=Homo sapiens OX=9606 GN=HSPD1 PE=1 SV=2" 5.84 2459.3 - 4.39E+07 - - - -3.4391 - 1.597 0.252 - 106.8 1 2 0 -0.0031 9 0 0 0 6.41E+10 5.22E+10 - - - 2.2556 0.999 221125_WJC_METTL3_EV_vs_WT_F02.10736.10736.2 0.00213 14-Aug K.WVPVTEPK[136.11].V sp|Q4VC05|BCL7A_HUMAN 1 962.5317 0.64 12056 10736 2 962.529969 482.2731 B-cell CLL\lymphoma 7 protein family member A OS=Homo sapiens OX=9606 GN=BCL7A PE=1 SV=1 6 2459.6 - 1.88E+06 - - - -1.7651 - 1.583 0.344 - 257.5 1 2 0 -0.0017 8 0 0 0 4.27E+07 6.64E+07 - - - 2.9665 0.9995 221125_WJC_METTL3_EV_vs_WT_F02.10740.10740.2 0.00504 14-Aug K.YFTEAGLK.E "sp|Q7L1Q6|BZW1_HUMAN,tr|C9IZ80|C9IZ80_HUMAN" 2 927.4702 0.25 12058 10740 2 927.470881 464.7424 Basic leucine zipper and W2 domain-containing protein 1 OS=Homo sapiens OX=9606 GN=BZW1 PE=1 SV=1 6 2460.1 - 2.87E+06 - - - 0.7526 - 1.384 0.421 - 153.4 1 2 0 0.0007 8 0 0 0 5.12E+07 2.09E+08 - - - 3.1304 0.9741 221125_WJC_METTL3_EV_vs_WT_F02.10743.10743.2 0.0379 14-Aug R.GLNISAVR[166.11].L "sp|P23588|IF4B_HUMAN,tr|E7EX17|E7EX17_HUMAN,tr|F8VSC7|F8VSC7_HUMAN,tr|F8VYE9|F8VYE9_HUMAN,tr|F8VRU1|F8VRU1_HUMAN,tr|F8VX11|F8VX11_HUMAN,tr|F8W0K0|F8W0K0_HUMAN,tr|F8VP89|F8VP89_HUMAN" 8 838.49 1.71 12059 10743 2 838.485199 420.2523 Eukaryotic translation initiation factor 4B OS=Homo sapiens OX=9606 GN=EIF4B PE=1 SV=2 9.75 2460.5 - 4.35E+06 - - - -5.7508 - 1.834 0.229 - 280.8 1 2 0 -0.0048 8 0 0 0 7.86E+08 4.58E+08 - - - 2.5601 0.9959 221125_WJC_METTL3_EV_vs_WT_F02.10745.10745.2 0.00381 14-Aug K.WVPVTEPK.V sp|Q4VC05|BCL7A_HUMAN 1 954.5175 0.63 12061 10745 2 954.514865 478.266 B-cell CLL\lymphoma 7 protein family member A OS=Homo sapiens OX=9606 GN=BCL7A PE=1 SV=1 6 2460.8 - 2.11E+06 - - - -2.727 - 1.617 0.24 - 296 1 2 0 -0.0026 8 0 0 0 4.22E+07 6.64E+07 - - - 2.2622 0.9443 221125_WJC_METTL3_EV_vs_WT_F02.10764.10764.2 0.78 14-Sep R.TVLFTNAR[166.11].K sp|P42285|MTREX_HUMAN 1 930.5162 0.84 12066 10764 2 930.520617 466.2654 Exosome RNA helicase MTR4 OS=Homo sapiens OX=9606 GN=MTREX PE=1 SV=3 9.41 2463.4 - 1.75E+06 - - - 4.7081 - 1.441 0.161 - 262.8 1 2 0 0.0044 8 0 0 0 8.42E+07 1.01E+08 - - - 1.3306 0.8903 221125_WJC_METTL3_EV_vs_WT_F02.10777.10777.2 0.438 12-Jun R.LDDSFVR[166.11].G "sp|Q99615|DNJC7_HUMAN,tr|K7ESP1|K7ESP1_HUMAN,tr|A0A6I8PRZ0|A0A6I8PRZ0_HUMAN,tr|A0A6I8PLE7|A0A6I8PLE7_HUMAN,tr|K7EJE9|K7EJE9_HUMAN,tr|A0A6I8PR89|A0A6I8PR89_HUMAN,tr|A0A6I8PIK4|A0A6I8PIK4_HUMAN,tr|K7ELJ8|K7ELJ8_HUMAN,tr|K7EN19|K7EN19_HUMAN,tr|A0A6I8PUC2|A0A6I8PUC2_HUMAN,tr|A0A6I8PS32|A0A6I8PS32_HUMAN,tr|K7EJL5|K7EJL5_HUMAN,tr|K7EPP7|K7EPP7_HUMAN,tr|A0A6I8PUD4|A0A6I8PUD4_HUMAN,tr|K7EIH8|K7EIH8_HUMAN,tr|K7ER44|K7ER44_HUMAN,tr|A0A6I8PU73|A0A6I8PU73_HUMAN,tr|K7EK03|K7EK03_HUMAN,tr|K7EJV7|K7EJV7_HUMAN,tr|A0A6I8PU89|A0A6I8PU89_HUMAN" 20 860.4268 0.59 12070 10777 2 860.42348 431.2207 DnaJ homolog subfamily C member 7 OS=Homo sapiens OX=9606 GN=DNAJC7 PE=1 SV=2 4.21 2465.1 - 4.25E+06 - - - -3.8028 - 1.166 0.111 - 100.7 1 2 0 -0.0033 7 0 0 0 1.51E+08 2.57E+08 - - - 0.3464 0.9556 221125_WJC_METTL3_EV_vs_WT_F02.10781.10781.2 0.0168 14-Sep R.LAELSDYR.R sp|Q96PK6|RBM14_HUMAN 1 965.4818 1.82 12072 10781 2 965.473986 483.7482 RNA-binding protein 14 OS=Homo sapiens OX=9606 GN=RBM14 PE=1 SV=2 4.37 2465.6 - 6.65E+06 - - - -8.1048 - 1.874 0.337 - 326.3 1 2 0 -0.0078 8 0 0 0 4.67E+09 2.57E+09 - - - 3.4219 0.9985 221125_WJC_METTL3_EV_vs_WT_F02.10782.10782.2 0.294 14-Oct R.LAELSDYR[166.11].R sp|Q96PK6|RBM14_HUMAN 1 975.4901 1.82 12073 10782 2 975.488299 488.7523 RNA-binding protein 14 OS=Homo sapiens OX=9606 GN=RBM14 PE=1 SV=2 4.37 2465.7 - 3.94E+06 - - - -1.8268 - 1.723 0.258 - 469.1 1 2 0 -0.0018 8 0 0 0 4.67E+09 2.57E+09 - - - 2.5869 0.9986 221125_WJC_METTL3_EV_vs_WT_F02.10799.10799.2 0.00383 16-Sep K.LIIVEGC[160.03]QR[166.11].Q "sp|P05023|AT1A1_HUMAN,sp|P13637|AT1A3_HUMAN,sp|Q13733|AT1A4_HUMAN,sp|P50993|AT1A2_HUMAN,sp|P54707|AT12A_HUMAN,tr|A0A0A0MT26|A0A0A0MT26_HUMAN,tr|H0Y7C1|H0Y7C1_HUMAN,tr|A0A2R8YEY8|A0A2R8YEY8_HUMAN,tr|B1AKY9|B1AKY9_HUMAN,tr|M0R116|M0R116_HUMAN" 10 1096.5938 1.03 12078 10799 2 1096.590424 549.3042 Sodium\potassium-transporting ATPase subunit alpha-1 OS=Homo sapiens OX=9606 GN=ATP1A1 PE=1 SV=1 5.99 2467.9 - 0 - - - -3.1105 - 1.919 0.363 - 306.5 1 2 0 -0.0034 9 0 0 0 1.00E+08 9.69E+07 - - - 3.6068 0.9911 221125_WJC_METTL3_EV_vs_WT_F02.10801.10801.2 0.94 16-Aug K.LIIVEGC[160.03]QR.Q "sp|P05023|AT1A1_HUMAN,sp|P13637|AT1A3_HUMAN,sp|Q13733|AT1A4_HUMAN,sp|P50993|AT1A2_HUMAN,sp|P54707|AT12A_HUMAN,tr|A0A0A0MT26|A0A0A0MT26_HUMAN,tr|H0Y7C1|H0Y7C1_HUMAN,tr|A0A2R8YEY8|A0A2R8YEY8_HUMAN,tr|B1AKY9|B1AKY9_HUMAN,tr|M0R116|M0R116_HUMAN" 10 1086.5856 1.03 12079 10801 2 1086.581373 544.3001 Sodium\potassium-transporting ATPase subunit alpha-1 OS=Homo sapiens OX=9606 GN=ATP1A1 PE=1 SV=1 5.99 2468.2 - 0 - - - -3.858 - 1.538 0.274 - 206.5 1 2 0 -0.0042 9 0 0 0 1.00E+08 9.69E+07 - - - 2.3089 0.9996 221125_WJC_METTL3_EV_vs_WT_F02.10806.10806.2 0.0201 14-Sep R.MMLEEQVR.S sp|Q01664|TFAP4_HUMAN 1 1034.4889 0.04 12081 10806 2 1034.48793 518.2517 Transcription factor AP-4 OS=Homo sapiens OX=9606 GN=TFAP4 PE=1 SV=2 4.53 2468.8 - 2.70E+06 - - - -0.9251 - 1.751 0.36 - 444.7 1 2 0 -0.001 8 0 0 0 9.11E+07 2.11E+09 - - - 3.3892 0.9431 221125_WJC_METTL3_EV_vs_WT_F02.10808.10808.2 0.747 12-Aug K.ITELQLK.L sp|P12270|TPR_HUMAN 1 843.5066 1.3 12082 10808 2 843.508558 422.7606 Nucleoprotein TPR OS=Homo sapiens OX=9606 GN=TPR PE=1 SV=3 6 2469 - 3.18E+06 - - - 2.358 - 1.262 0.051 - 145.5 1 2 0 0.002 7 0 0 0 5.64E+07 4.34E+07 - - - 0.1544 0.8852 221125_WJC_METTL3_EV_vs_WT_F02.10811.10811.2 0.059 12-Jul R.LAVYIDK.V "sp|P20700|LMNB1_HUMAN,tr|A0A0D9SFY5|A0A0D9SFY5_HUMAN,tr|E9PBF6|E9PBF6_HUMAN,tr|A0A0D9SFE5|A0A0D9SFE5_HUMAN" 4 820.4695 0.68 12084 10811 2 820.462716 411.242 Lamin-B1 OS=Homo sapiens OX=9606 GN=LMNB1 PE=1 SV=2 5.83 2469.3 - 3.35E+06 - - - -8.2136 - 1.639 0.249 - 186 1 2 0 -0.0067 7 0 0 0 5.15E+08 7.54E+08 - - - 2.4435 0.9686 221125_WJC_METTL3_EV_vs_WT_F02.10818.10818.2 2.19 14-Jul R.TLLVADPR[166.11].R "sp|P62249|RS16_HUMAN,tr|M0R210|M0R210_HUMAN" 2 893.521 0.83 12085 10818 2 893.519652 447.7678 40S ribosomal protein S16 OS=Homo sapiens OX=9606 GN=RPS16 PE=1 SV=2 5.5 2470.4 - 1.37E+07 - - - -1.4941 - 1.205 0.073 - 166.2 1 2 0 -0.0013 8 0 0 0 5.16E+09 6.25E+09 - - - 0.1422 0.9921 221125_WJC_METTL3_EV_vs_WT_F02.10820.10820.2 0.475 14-Jul R.TLLVADPR.R "sp|P62249|RS16_HUMAN,tr|M0R210|M0R210_HUMAN" 2 883.5127 0.83 12086 10820 2 883.51202 442.7636 40S ribosomal protein S16 OS=Homo sapiens OX=9606 GN=RPS16 PE=1 SV=2 5.5 2470.6 - 1.12E+07 - - - -0.7889 - 1.434 0.098 - 171.2 1 2 0 -0.0007 8 0 0 0 5.15E+09 6.24E+09 - - - 0.8518 0.8934 221125_WJC_METTL3_EV_vs_WT_F02.10822.10822.2 3.23 12-May R.YLYYTGR.L sp|O43242|PSMD3_HUMAN 1 934.4549 0.25 12087 10822 2 934.452611 468.2347 26S proteasome non-ATPase regulatory subunit 3 OS=Homo sapiens OX=9606 GN=PSMD3 PE=1 SV=2 8.5 2470.8 - 1.74E+06 - - - -2.4153 - 1.128 0.04 - 76.5 1 2 0 -0.0023 7 0 0 0 2.50E+07 1.01E+08 - - - -0.2826 0.9974 221125_WJC_METTL3_EV_vs_WT_F02.10828.10828.2 0.00819 16-Oct R.LLQVDPEAR.L "sp|P15735|PHKG2_HUMAN,tr|J3KNN3|J3KNN3_HUMAN" 2 1039.5662 0.96 12089 10828 2 1039.56225 520.7904 "Phosphorylase b kinase gamma catalytic chain, liver\testis isoform OS=Homo sapiens OX=9606 GN=PHKG2 PE=1 SV=1" 4.37 2471.6 - 2.18E+06 - - - -3.8083 - 1.974 0.339 - 348.5 1 2 0 -0.004 9 0 0 0 7.36E+07 7.67E+07 - - - 3.5111 0.9931 221125_WJC_METTL3_EV_vs_WT_F02.10831.10831.2 1.67E-05 18-Nov K.LGNEVGYSIR.F "sp|O60231|DHX16_HUMAN,tr|A0A140T947|A0A140T947_HUMAN" 2 1106.572 1.62 12090 10831 2 1106.564956 554.2933 Pre-mRNA-splicing factor ATP-dependent RNA helicase DHX16 OS=Homo sapiens OX=9606 GN=DHX16 PE=1 SV=2 6 2472 - 2.04E+06 - - - -6.3864 - 2.191 0.463 - 392.8 1 2 0 -0.0071 10 0 0 0 9.03E+07 5.56E+07 - - - 4.6479 0.961 221125_WJC_METTL3_EV_vs_WT_F02.10832.10832.2 3.42 14-Aug R.ISEIIDSR.R sp|P27986|P85A_HUMAN 1 931.4975 13.03 12091 10832 2 931.497944 466.756 Phosphatidylinositol 3-kinase regulatory subunit alpha OS=Homo sapiens OX=9606 GN=PIK3R1 PE=1 SV=2 4.37 2472.1 - 1.07E+06 - - - 0.5185 - 1.229 0.016 - 165.9 1 2 0 0.0005 8 0 0 0 6.27E+07 4.81E+06 - - - -0.2191 0.9977 221125_WJC_METTL3_EV_vs_WT_F02.10836.10836.2 0.644 14-Jun K.EILSEVER[166.11].N "sp|P49368|TCPG_HUMAN,tr|B4DUR8|B4DUR8_HUMAN" 2 983.5163 0.23 12093 10836 2 983.516265 492.7654 T-complex protein 1 subunit gamma OS=Homo sapiens OX=9606 GN=CCT3 PE=1 SV=4 4.25 2472.6 - 5.31E+06 - - - -0.0315 - 1.366 0.232 - 146.6 1 2 0 0 8 0 0 0 2.50E+08 1.07E+09 - - - 1.6952 0.9999 221125_WJC_METTL3_EV_vs_WT_F02.10837.10837.2 0.00131 13/18 K.LGNEVGYSIR[166.11].F "sp|O60231|DHX16_HUMAN,tr|A0A140T947|A0A140T947_HUMAN" 2 1116.5803 1.62 12094 10837 2 1116.579669 559.2974 Pre-mRNA-splicing factor ATP-dependent RNA helicase DHX16 OS=Homo sapiens OX=9606 GN=DHX16 PE=1 SV=2 6 2472.7 - 1.96E+06 - - - -0.5588 - 2.476 0.419 - 728.3 1 2 0 -0.0006 10 0 0 0 9.00E+07 5.56E+07 - - - 4.6663 0.9937 221125_WJC_METTL3_EV_vs_WT_F02.10839.10839.2 0.0407 18-Nov K.GAVAMAETLK[136.11].T "sp|P46060|RAGP1_HUMAN,tr|H0Y4Q3|H0Y4Q3_HUMAN" 2 997.5358 1.08 12096 10839 2 997.532206 499.7752 Ran GTPase-activating protein 1 OS=Homo sapiens OX=9606 GN=RANGAP1 PE=1 SV=1 6 2472.9 - 1.48E+06 - - - -3.5698 - 2.141 0.172 - 373.3 1 2 0 -0.0036 10 0 0 0 1.17E+08 1.08E+08 - - - 2.4352 0.9985 221125_WJC_METTL3_EV_vs_WT_F02.10845.10845.2 0.127 14-Aug R.SILPTAPR[166.11].A "sp|P23588|IF4B_HUMAN,tr|E7EX17|E7EX17_HUMAN,tr|F8VSC7|F8VSC7_HUMAN,tr|F8VYE9|F8VYE9_HUMAN,tr|F8VRU1|F8VRU1_HUMAN,tr|F8VX11|F8VX11_HUMAN,tr|F8W0K0|F8W0K0_HUMAN,tr|F8VP89|F8VP89_HUMAN" 8 863.5104 15.77 12098 10845 2 863.510418 432.7625 Eukaryotic translation initiation factor 4B OS=Homo sapiens OX=9606 GN=EIF4B PE=1 SV=2 9.47 2473.7 - 3.74E+06 - - - -0.0046 - 1.429 0.261 - 183.8 1 2 0 0 8 0 0 0 5.41E+09 3.43E+08 - - - 2.0454 0.9968 221125_WJC_METTL3_EV_vs_WT_F02.10852.10852.2 0.00839 16-Oct K.IVFVTGNAK[136.11].K sp|Q9BY32|ITPA_HUMAN 1 955.5582 0.39 12103 10852 2 955.554099 478.7864 Inosine triphosphate pyrophosphatase OS=Homo sapiens OX=9606 GN=ITPA PE=1 SV=2 8.75 2474.5 - 829576 - - - -4.3095 - 2.069 0.342 - 240.4 1 2 0 -0.0041 9 0 0 0 2.31E+07 5.89E+07 - - - 3.6692 0.9997 221125_WJC_METTL3_EV_vs_WT_F02.10855.10855.2 6.30E-05 20-Sep K.LGEGTYATVYK[136.11].G "sp|Q00537|CDK17_HUMAN,sp|Q00536|CDK16_HUMAN,tr|F5H6Z0|F5H6Z0_HUMAN,tr|E5RJM2|E5RJM2_HUMAN,tr|E5RGN0|E5RGN0_HUMAN,tr|H0YBX5|H0YBX5_HUMAN,tr|A0A087WZU2|A0A087WZU2_HUMAN" 7 1208.6169 1.15 12104 10855 2 1208.614918 605.3157 Cyclin-dependent kinase 17 OS=Homo sapiens OX=9606 GN=CDK17 PE=1 SV=2 6 2474.9 - 940111 - - - -1.6018 - 2.074 0.466 - 208.8 1 2 0 -0.0019 11 0 0 0 4.77E+07 4.15E+07 - - - 4.4557 0.9913 221125_WJC_METTL3_EV_vs_WT_F02.10858.10858.2 0.395 16-Aug R.GLTETGLYR[166.11].L "sp|Q9H0H5|RGAP1_HUMAN,tr|H0YIK5|H0YIK5_HUMAN" 2 1018.5323 0.63 12107 10858 2 1018.532982 510.2734 Rac GTPase-activating protein 1 OS=Homo sapiens OX=9606 GN=RACGAP1 PE=1 SV=1 6 2475.1 - 2.36E+06 - - - 0.6892 - 1.256 0.151 - 141.6 1 2 0 0.0007 9 0 0 0 4.08E+07 6.50E+07 - - - 0.8155 0.9949 221125_WJC_METTL3_EV_vs_WT_F02.10861.10861.2 0.12 16-Sep K.IVFVTGNAK.K sp|Q9BY32|ITPA_HUMAN 1 947.544 0.41 12108 10861 2 947.54515 474.7793 Inosine triphosphate pyrophosphatase OS=Homo sapiens OX=9606 GN=ITPA PE=1 SV=2 8.75 2475.5 - 1.49E+06 - - - 1.1957 - 1.499 0.155 - 164.2 1 2 0 0.0011 9 0 0 0 2.31E+07 5.69E+07 - - - 1.3566 0.9954 221125_WJC_METTL3_EV_vs_WT_F02.10862.10862.2 0.127 14-Jul K.GYFAVTEK[136.11].C "sp|Q13045|FLII_HUMAN,tr|K7EQZ7|K7EQZ7_HUMAN,tr|J3QLR6|J3QLR6_HUMAN" 3 921.4687 0.92 12109 10862 2 921.467518 461.7416 Protein flightless-1 homolog OS=Homo sapiens OX=9606 GN=FLII PE=1 SV=2 6 2475.7 - 912250 - - - -1.3185 - 1.325 0.206 - 156.8 1 2 0 -0.0012 8 0 0 0 3.89E+07 4.22E+07 - - - 1.4109 0.8373 221125_WJC_METTL3_EV_vs_WT_F02.10864.10864.2 0.00133 16-Sep F.WAPESAPLK[136.11].S "sp|P23528|COF1_HUMAN,sp|Q9Y281|COF2_HUMAN,tr|E9PP50|E9PP50_HUMAN,tr|G3V1A4|G3V1A4_HUMAN,tr|E9PQB7|E9PQB7_HUMAN,tr|E9PK25|E9PK25_HUMAN" 6 1005.5375 1.73 12111 10864 2 1005.541078 503.776 Cofilin-1 OS=Homo sapiens OX=9606 GN=CFL1 PE=1 SV=3 6 2475.9 - 1.51E+06 - - - 3.5762 - 1.714 0.339 - 359.4 1 1 0 0.0036 9 0 0 0 4.45E+08 2.57E+08 - - - 3.1026 0.999 221125_WJC_METTL3_EV_vs_WT_F02.10874.10874.2 0.0637 12-Aug R.LAVYIDK[136.11].V "sp|P20700|LMNB1_HUMAN,tr|A0A0D9SFY5|A0A0D9SFY5_HUMAN,tr|E9PBF6|E9PBF6_HUMAN,tr|A0A0D9SFE5|A0A0D9SFE5_HUMAN" 4 828.4837 1.06 12116 10874 2 828.482719 415.2491 Lamin-B1 OS=Homo sapiens OX=9606 GN=LMNB1 PE=1 SV=2 5.83 2477.1 - 8.21E+06 - - - -1.1298 - 1.599 0.273 - 221.2 1 2 0 -0.0009 7 0 0 0 4.99E+08 4.70E+08 - - - 2.5443 0.9999 221125_WJC_METTL3_EV_vs_WT_F02.10878.10878.2 5.51E-06 20-Nov K.LGEGTYATVYK.G "sp|Q00537|CDK17_HUMAN,sp|Q00536|CDK16_HUMAN,tr|F5H6Z0|F5H6Z0_HUMAN,tr|E5RJM2|E5RJM2_HUMAN,tr|E5RGN0|E5RGN0_HUMAN,tr|H0YBX5|H0YBX5_HUMAN,tr|A0A087WZU2|A0A087WZU2_HUMAN" 7 1200.6027 1.15 12119 10878 2 1200.60339 601.3086 Cyclin-dependent kinase 17 OS=Homo sapiens OX=9606 GN=CDK17 PE=1 SV=2 6 2477.4 - 1.03E+06 - - - 0.613 - 2.419 0.486 - 360.8 1 2 0 0.0007 11 0 0 0 4.77E+07 4.16E+07 - - - 5.02 0.9787 221125_WJC_METTL3_EV_vs_WT_F02.10881.10881.2 3.42 12-May R.ELIIGDR.Q "sp|P25705|ATPA_HUMAN,tr|K7EK77|K7EK77_HUMAN,tr|K7ENJ4|K7ENJ4_HUMAN" 3 814.4549 1.27 12120 10881 2 814.453526 408.2347 "ATP synthase subunit alpha, mitochondrial OS=Homo sapiens OX=9606 GN=ATP5F1A PE=1 SV=1" 4.37 2477.8 - 1.58E+07 - - - -1.6477 - 1.204 0.113 - 99.7 1 2 0 -0.0013 7 0 0 0 1.12E+09 8.87E+08 - - - 0.4634 0.9961 221125_WJC_METTL3_EV_vs_WT_F02.10883.10883.2 0.00885 16-Oct R.LLQVDPEAR[166.11].L "sp|P15735|PHKG2_HUMAN,tr|J3KNN3|J3KNN3_HUMAN" 2 1049.5745 1.06 12122 10883 2 1049.569486 525.7945 "Phosphorylase b kinase gamma catalytic chain, liver\testis isoform OS=Homo sapiens OX=9606 GN=PHKG2 PE=1 SV=1" 4.37 2478 - 1.33E+06 - - - -4.7572 - 1.98 0.384 - 359.8 1 2 0 -0.005 9 0 0 0 8.28E+07 7.78E+07 - - - 3.8519 0.9997 221125_WJC_METTL3_EV_vs_WT_F02.10884.10884.2 7.60E-05 16-Sep K.LEMEMEAAR[166.11].H "sp|Q15233|NONO_HUMAN,tr|A0A7I2V535|A0A7I2V535_HUMAN,tr|A0A7I2V4N2|A0A7I2V4N2_HUMAN,tr|A0A7I2V4K9|A0A7I2V4K9_HUMAN,tr|A0A7I2V464|A0A7I2V464_HUMAN,tr|A0A7P0MRW0|A0A7P0MRW0_HUMAN,tr|H7C367|H7C367_HUMAN,tr|A0A7I2V4J2|A0A7I2V4J2_HUMAN,tr|A0A7I2V5Y7|A0A7I2V5Y7_HUMAN,tr|C9JYS8|C9JYS8_HUMAN" 10 1088.487 0.77 12123 10884 2 1088.484666 545.2508 Non-POU domain-containing octamer-binding protein OS=Homo sapiens OX=9606 GN=NONO PE=1 SV=4 4.25 2478.2 - 1.27E+06 - - - -2.1314 - 1.901 0.552 - 287.9 1 2 0 -0.0023 9 0 0 0 4.29E+07 5.56E+07 - - - 4.9758 0.9996 221125_WJC_METTL3_EV_vs_WT_F02.10890.10890.2 0.00131 16-Oct K.LEMEMEAAR.H "sp|Q15233|NONO_HUMAN,tr|A0A7I2V535|A0A7I2V535_HUMAN,tr|A0A7I2V4N2|A0A7I2V4N2_HUMAN,tr|A0A7I2V4K9|A0A7I2V4K9_HUMAN,tr|A0A7I2V464|A0A7I2V464_HUMAN,tr|A0A7P0MRW0|A0A7P0MRW0_HUMAN,tr|H7C367|H7C367_HUMAN,tr|A0A7I2V4J2|A0A7I2V4J2_HUMAN,tr|A0A7I2V5Y7|A0A7I2V5Y7_HUMAN,tr|C9JYS8|C9JYS8_HUMAN" 10 1078.4787 0.71 12125 10890 2 1078.476889 540.2466 Non-POU domain-containing octamer-binding protein OS=Homo sapiens OX=9606 GN=NONO PE=1 SV=4 4.25 2478.9 - 569915 - - - -1.6941 - 1.743 0.431 - 255.5 1 2 0 -0.0018 9 0 0 0 3.89E+07 5.50E+07 - - - 3.8312 0.8013 221125_WJC_METTL3_EV_vs_WT_F02.10891.10891.2 3.73 12-Jul K.SAFPLSR.K "sp|Q9NYR9|KBRS2_HUMAN,tr|H7BXP1|H7BXP1_HUMAN" 2 776.4181 0.58 12126 10891 2 776.420259 389.2163 NF-kappa-B inhibitor-interacting Ras-like protein 2 OS=Homo sapiens OX=9606 GN=NKIRAS2 PE=1 SV=1 9.47 2479.1 - 1.09E+06 - - - 2.7962 - 1.131 0.022 - 155.5 2 2 0 0.0022 7 0 0 0 6.43E+07 1.10E+08 - - - -0.5416 0.9668 221125_WJC_METTL3_EV_vs_WT_F02.10892.10892.2 0.0499 18-Sep K.GAVAMAETLK.T "sp|P46060|RAGP1_HUMAN,tr|H0Y4Q3|H0Y4Q3_HUMAN" 2 989.5216 1.16 12127 10892 2 989.516279 495.7681 Ran GTPase-activating protein 1 OS=Homo sapiens OX=9606 GN=RANGAP1 PE=1 SV=1 6 2479.1 - 1.91E+06 - - - -5.344 - 1.704 0.211 - 186.5 1 2 0 -0.0053 10 0 0 0 1.26E+08 1.08E+08 - - - 2.0855 0.9979 221125_WJC_METTL3_EV_vs_WT_F02.10896.10896.2 0.47 14-Jul K.EILSEVER.N "sp|P49368|TCPG_HUMAN,tr|B4DUR8|B4DUR8_HUMAN" 2 973.508 0.23 12128 10896 2 973.506995 487.7613 T-complex protein 1 subunit gamma OS=Homo sapiens OX=9606 GN=CCT3 PE=1 SV=4 4.25 2479.7 - 7.03E+06 - - - -1.0591 - 1.45 0.237 - 198.8 1 2 0 -0.001 8 0 0 0 2.51E+08 1.08E+09 - - - 1.9118 0.8718 221125_WJC_METTL3_EV_vs_WT_F02.10900.10900.2 0.025 12-Jul P.LVPYPEK[136.11].S sp|Q96LX8|ZN597_HUMAN 1 852.4837 0.04 12131 10900 2 852.484366 427.2491 Zinc finger protein 597 OS=Homo sapiens OX=9606 GN=ZNF597 PE=1 SV=1 6 2480 - 3.26E+06 - - - 0.834 - 1.183 0.301 - 152.6 1 1 0 0.0007 7 0 0 0 9.88E+06 2.48E+08 - - - 1.7965 0.9948 221125_WJC_METTL3_EV_vs_WT_F02.10908.10908.2 0.00631 20-Aug K.VLTPEEQLADK[136.11].L sp|O75822|EIF3J_HUMAN 1 1249.6645 1.15 12135 10908 2 1249.662054 625.8395 Eukaryotic translation initiation factor 3 subunit J OS=Homo sapiens OX=9606 GN=EIF3J PE=1 SV=2 4.14 2481.1 - 439769 - - - -1.9837 - 1.44 0.218 - 175.5 1 2 0 -0.0025 11 0 0 0 2.49E+07 2.17E+07 - - - 1.6368 0.9965 221125_WJC_METTL3_EV_vs_WT_F02.10914.10914.2 4.26 12-Jul R.ELAELVK.R "sp|Q9HAF1|EAF6_HUMAN,sp|Q6UVM3|KCNT2_HUMAN" 2 800.4644 1.61 12137 10914 2 800.463905 401.2395 Chromatin modification-related protein MEAF6 OS=Homo sapiens OX=9606 GN=MEAF6 PE=1 SV=1 4.53 2481.9 - 3.51E+06 - - - -0.5809 - 1.598 0.119 - 260.5 1 2 0 -0.0005 7 0 0 0 3.23E+08 2.00E+08 - - - 1.4051 0.9783 221125_WJC_METTL3_EV_vs_WT_F02.10915.10915.2 13.7 12-Jul R.ELAELVK[136.11].R "sp|Q9HAF1|EAF6_HUMAN,sp|Q6UVM3|KCNT2_HUMAN" 2 808.4786 1.61 12138 10915 2 808.476163 405.2466 Chromatin modification-related protein MEAF6 OS=Homo sapiens OX=9606 GN=MEAF6 PE=1 SV=1 4.53 2481.9 - 2.51E+06 - - - -2.9772 - 1.479 0.111 - 195 1 2 0 -0.0024 7 0 0 0 3.23E+08 2.01E+08 - - - 1.1002 0.9996 221125_WJC_METTL3_EV_vs_WT_F02.10924.10924.2 0.0855 14-Sep K.VYIIQAC[160.03]R.G sp|P31944|CASPE_HUMAN 1 1021.5379 35.16 12142 10924 2 1021.537819 511.7762 Caspase-14 OS=Homo sapiens OX=9606 GN=CASP14 PE=1 SV=2 8.19 2483 - 1.40E+06 - - - -0.0656 - 1.792 0.317 - 411.4 1 2 0 -0.0001 8 0 0 0 6.63E+07 1.88E+06 - - - 3.1416 0.9908 221125_WJC_METTL3_EV_vs_WT_F02.10925.10925.2 0.384 12-Jul K.FIGELGK.L "sp|P78344|IF4G2_HUMAN,tr|H0YEC5|H0YEC5_HUMAN,tr|H0Y3P2|H0Y3P2_HUMAN,tr|H0YCH5|H0YCH5_HUMAN,tr|H0YD77|H0YD77_HUMAN,tr|D3DQV9|D3DQV9_HUMAN" 6 762.4276 1.77 12143 10925 2 762.428715 382.2211 Eukaryotic translation initiation factor 4 gamma 2 OS=Homo sapiens OX=9606 GN=EIF4G2 PE=1 SV=1 6 2483.1 - 1.22E+06 - - - 1.4755 - 1.36 0.139 - 166.2 1 2 0 0.0011 7 0 0 0 1.83E+08 1.03E+08 - - - 1.0416 0.8788 221125_WJC_METTL3_EV_vs_WT_F02.10926.10926.2 1.41 20-Jul R.NLVVSLMSSMK[136.11].S "sp|Q15878|CAC1E_HUMAN,tr|J3KP11|J3KP11_HUMAN,tr|F8W9Z1|F8W9Z1_HUMAN" 3 1215.6447 0.001 12144 10926 2 1215.640702 608.8296 Voltage-dependent R-type calcium channel subunit alpha-1E OS=Homo sapiens OX=9606 GN=CACNA1E PE=1 SV=3 8.75 2483.3 - 297076 - - - -3.2608 - 1.266 0.046 - 92.7 1 2 0 -0.004 11 0 0 0 0.00E+00 1.70E+07 - - - 0.0176 0.9402 221125_WJC_METTL3_EV_vs_WT_F02.10929.10929.2 9.35 12-Jun K.FIGELGK[136.11].L "sp|P78344|IF4G2_HUMAN,tr|H0YEC5|H0YEC5_HUMAN,tr|H0Y3P2|H0Y3P2_HUMAN,tr|H0YCH5|H0YCH5_HUMAN,tr|H0YD77|H0YD77_HUMAN,tr|D3DQV9|D3DQV9_HUMAN" 6 770.4418 2.01 12145 10929 2 770.441164 386.2282 Eukaryotic translation initiation factor 4 gamma 2 OS=Homo sapiens OX=9606 GN=EIF4G2 PE=1 SV=1 6 2483.6 - 1.17E+06 - - - -0.8125 - 1.039 0.084 - 120.5 4 2 0 -0.0006 7 0 0 0 2.13E+08 1.06E+08 - - - -0.4865 0.9988 221125_WJC_METTL3_EV_vs_WT_F02.10931.10931.2 0.0442 14-Jul R.LGPLQVAR.V sp|P38117|ETFB_HUMAN 1 852.5181 1.57 12146 10931 2 852.517488 427.2663 Electron transfer flavoprotein subunit beta OS=Homo sapiens OX=9606 GN=ETFB PE=1 SV=3 9.75 2483.9 - 5.05E+06 - - - -0.7613 - 1.492 0.278 - 136.1 1 2 0 -0.0006 8 0 0 0 5.50E+08 3.49E+08 - - - 2.3008 0.9996 221125_WJC_METTL3_EV_vs_WT_F02.10935.10935.2 0.084 13/22 R.ALEEANADLEVK.L "sp|P02533|K1C14_HUMAN,sp|P08779|K1C16_HUMAN,sp|P19012|K1C15_HUMAN,sp|P13646|K1C13_HUMAN,tr|K7EMD9|K7EMD9_HUMAN,tr|K7ERE3|K7ERE3_HUMAN" 6 1300.6511 256.53 12148 10935 2 1300.653193 651.3328 "Keratin, type I cytoskeletal 14 OS=Homo sapiens OX=9606 GN=KRT14 PE=1 SV=4" 4 2484.4 - 766276 - - - 1.6392 - 2.308 0.371 - 591.7 1 2 0 0.0021 12 0 0 0 2.94E+07 1.15E+05 - - - 3.9812 0.9996 221125_WJC_METTL3_EV_vs_WT_F02.10937.10937.2 0.00877 16-Aug K.AINTLNGLR.L "sp|Q12926|ELAV2_HUMAN,sp|P26378|ELAV4_HUMAN,sp|Q15717|ELAV1_HUMAN,tr|A0A494C0Q5|A0A494C0Q5_HUMAN,tr|A0A494C0M6|A0A494C0M6_HUMAN,tr|B1AM48|B1AM48_HUMAN,tr|A0A494C0F8|A0A494C0F8_HUMAN,tr|M0QZR9|M0QZR9_HUMAN,tr|A0A494C147|A0A494C147_HUMAN,tr|A0A494C015|A0A494C015_HUMAN,tr|A0A494C1D9|A0A494C1D9_HUMAN,tr|A0A0R4J2E6|A0A0R4J2E6_HUMAN,tr|A0A494C173|A0A494C173_HUMAN,tr|A0A0A0MRX1|A0A0A0MRX1_HUMAN,tr|A0A494C011|A0A494C011_HUMAN,tr|B1APY9|B1APY9_HUMAN" 16 970.556 1.4 12149 10937 2 970.556749 486.2853 ELAV-like protein 2 OS=Homo sapiens OX=9606 GN=ELAVL2 PE=1 SV=2 9.79 2484.6 - 1.72E+06 - - - 0.7934 - 1.781 0.363 - 205.2 1 2 0 0.0008 9 0 0 0 7.03E+08 5.03E+08 - - - 3.3917 0.9994 221125_WJC_METTL3_EV_vs_WT_F02.10945.10945.2 0.0205 14-Sep R.LGPLQVAR[166.11].V sp|P38117|ETFB_HUMAN 1 862.5264 1.58 12153 10945 2 862.526995 432.2705 Electron transfer flavoprotein subunit beta OS=Homo sapiens OX=9606 GN=ETFB PE=1 SV=3 9.75 2485.5 - 7.44E+06 - - - 0.6817 - 1.865 0.288 - 263.1 1 2 0 0.0006 8 0 0 0 5.50E+08 3.49E+08 - - - 3.0477 0.9983 221125_WJC_METTL3_EV_vs_WT_F02.10947.10947.2 0.209 16-Nov K.AINTLNGLR[166.11].L "sp|Q12926|ELAV2_HUMAN,sp|P26378|ELAV4_HUMAN,sp|Q15717|ELAV1_HUMAN,tr|A0A494C0Q5|A0A494C0Q5_HUMAN,tr|A0A494C0M6|A0A494C0M6_HUMAN,tr|B1AM48|B1AM48_HUMAN,tr|A0A494C0F8|A0A494C0F8_HUMAN,tr|M0QZR9|M0QZR9_HUMAN,tr|A0A494C147|A0A494C147_HUMAN,tr|A0A494C015|A0A494C015_HUMAN,tr|A0A494C1D9|A0A494C1D9_HUMAN,tr|A0A0R4J2E6|A0A0R4J2E6_HUMAN,tr|A0A494C173|A0A494C173_HUMAN,tr|A0A0A0MRX1|A0A0A0MRX1_HUMAN,tr|A0A494C011|A0A494C011_HUMAN,tr|B1APY9|B1APY9_HUMAN" 16 980.5642 1.39 12155 10947 2 980.565463 491.2894 ELAV-like protein 2 OS=Homo sapiens OX=9606 GN=ELAVL2 PE=1 SV=2 9.79 2485.7 - 2.94E+06 - - - 1.2381 - 1.783 0.211 - 451.4 1 2 0 0.0012 9 0 0 0 7.01E+08 5.03E+08 - - - 2.2721 0.8208 221125_WJC_METTL3_EV_vs_WT_F02.10951.10951.2 16.1 16-Jul K.LADFGVSAK[136.11].N "sp|Q9H2G2|SLK_HUMAN,sp|O94804|STK10_HUMAN" 2 914.4953 0.54 12157 10951 2 914.493168 458.2549 STE20-like serine\threonine-protein kinase OS=Homo sapiens OX=9606 GN=SLK PE=1 SV=1 5.84 2486.1 - 1.26E+06 - - - -2.3128 - 1.097 0.017 - 84.6 2 2 0 -0.0021 9 0 0 0 2.90E+07 5.37E+07 - - - -0.7007 0.9983 221125_WJC_METTL3_EV_vs_WT_F02.10958.10958.2 0.00841 14-Aug K.IYQYVINK[136.11].E "sp|P17812|PYRG1_HUMAN,tr|A0A3B3ITH9|A0A3B3ITH9_HUMAN,tr|A0A3B3ITF6|A0A3B3ITF6_HUMAN,tr|A0A3B3IRQ8|A0A3B3IRQ8_HUMAN,tr|A0A3B3ITB8|A0A3B3ITB8_HUMAN,tr|A0A3B3IRI2|A0A3B3IRI2_HUMAN" 6 1047.5844 1.11 12161 10958 2 1047.586699 524.7995 CTP synthase 1 OS=Homo sapiens OX=9606 GN=CTPS1 PE=1 SV=2 8.5 2486.9 - 297643 - - - 2.164 - 1.382 0.374 - 169.8 1 2 0 0.0023 8 0 0 0 2.08E+07 1.88E+07 - - - 2.7784 0.9323 221125_WJC_METTL3_EV_vs_WT_F02.10959.10959.2 5.97 14-May R.VQELPLAR.L "sp|Q13952|NFYC_HUMAN,tr|E9PQR2|E9PQR2_HUMAN,tr|Q5T6K5|Q5T6K5_HUMAN,tr|E9PJA8|E9PJA8_HUMAN,tr|A0A0A0MT00|A0A0A0MT00_HUMAN,tr|Q5T6K7|Q5T6K7_HUMAN,tr|E9PI99|E9PI99_HUMAN" 7 924.5393 0.55 12162 10959 2 924.540146 463.2769 Nuclear transcription factor Y subunit gamma OS=Homo sapiens OX=9606 GN=NFYC PE=1 SV=3 5.97 2487 - 326447 - - - 0.9518 - 1.21 0.048 - 74.5 10 2 0 0.0009 8 0 0 0 1.04E+07 1.90E+07 - - - -0.4765 0.9638 221125_WJC_METTL3_EV_vs_WT_F02.10964.10964.2 0.0537 14-Aug K.YNTMLGYK.R "sp|Q9UM63|PLAL1_HUMAN,tr|A0A0D9SGF7|A0A0D9SGF7_HUMAN,tr|A0A3B3IRN7|A0A3B3IRN7_HUMAN,tr|A0A0D9SEQ4|A0A0D9SEQ4_HUMAN,tr|A0A0D9SFM8|A0A0D9SFM8_HUMAN,tr|A0A0D9SFI7|A0A0D9SFI7_HUMAN" 6 988.4688 0.91 12164 10964 2 988.474281 495.2417 Zinc finger protein PLAGL1 OS=Homo sapiens OX=9606 GN=PLAGL1 PE=1 SV=2 8.5 2487.6 - 356241 - - - 5.5419 - 1.289 0.317 - 151.4 1 2 0 0.0055 8 0 0 0 6.85E+06 7.51E+06 - - - 2.1463 0.9936 221125_WJC_METTL3_EV_vs_WT_F02.10966.10966.2 0.21 16-Aug K.LSDGVAVLK[136.11].V "sp|P10809|CH60_HUMAN,tr|A0A7I2V2X6|A0A7I2V2X6_HUMAN,tr|A0A7I2YQK6|A0A7I2YQK6_HUMAN,tr|A0A7I2V599|A0A7I2V599_HUMAN" 4 908.5422 1.75 12165 10966 2 908.5448 455.2784 "60 kDa heat shock protein, mitochondrial OS=Homo sapiens OX=9606 GN=HSPD1 PE=1 SV=2" 5.84 2487.9 - 1.44E+06 - - - 2.8254 - 1.671 0.196 - 108.4 1 2 0 0.0026 9 0 0 0 2.49E+08 1.42E+08 - - - 1.9732 0.9649 221125_WJC_METTL3_EV_vs_WT_F02.10970.10970.2 5.04 12-Jun K.FVVDVDK[136.11].N "sp|P62195|PRS8_HUMAN,tr|J3KRP2|J3KRP2_HUMAN,tr|J3QSA9|J3QSA9_HUMAN,tr|J3QLH6|J3QLH6_HUMAN,tr|J3QRW1|J3QRW1_HUMAN" 5 828.4473 0.66 12167 10970 2 828.448881 415.2309 26S proteasome regulatory subunit 8 OS=Homo sapiens OX=9606 GN=PSMC5 PE=1 SV=1 4.21 2488.4 - 2.78E+06 - - - 1.9446 - 1.181 0.1 - 124.7 1 2 0 0.0016 7 0 0 0 5.13E+07 7.81E+07 - - - 0.3062 0.9918 221125_WJC_METTL3_EV_vs_WT_F02.10971.10971.2 0.195 12-Jun K.FVVDVDK.N "sp|P62195|PRS8_HUMAN,tr|J3KRP2|J3KRP2_HUMAN,tr|J3QSA9|J3QSA9_HUMAN,tr|J3QLH6|J3QLH6_HUMAN,tr|J3QRW1|J3QRW1_HUMAN" 5 820.4331 0.62 12168 10971 2 820.433094 411.2238 26S proteasome regulatory subunit 8 OS=Homo sapiens OX=9606 GN=PSMC5 PE=1 SV=1 4.21 2488.4 - 2.13E+06 - - - 0.0293 - 1.157 0.169 - 137.4 1 2 0 0 7 0 0 0 4.58E+07 7.42E+07 - - - 0.7513 0.9998 221125_WJC_METTL3_EV_vs_WT_F02.10973.10973.2 7.72E-05 18-Sep R.AFAGPLSPAK.A sp|Q86XL3|ANKL2_HUMAN 1 957.5284 5.58 12170 10973 2 957.528502 479.7715 Ankyrin repeat and LEM domain-containing protein 2 OS=Homo sapiens OX=9606 GN=ANKLE2 PE=1 SV=4 8.8 2488.6 - 434087 - - - 0.141 - 1.802 0.449 - 205.1 1 2 0 0.0001 10 0 0 0 3.27E+07 5.86E+06 - - - 4.0011 0.9951 221125_WJC_METTL3_EV_vs_WT_F02.10976.10976.2 0.685 14-Jul K.YGVTTIVR[166.11].V "sp|Q93096|TP4A1_HUMAN,sp|Q12974|TP4A2_HUMAN,tr|E9PRR9|E9PRR9_HUMAN,tr|E9PMY3|E9PMY3_HUMAN,tr|E9PJC0|E9PJC0_HUMAN,tr|E9PML8|E9PML8_HUMAN,tr|A0A0D9SGK2|A0A0D9SGK2_HUMAN" 7 917.521 1.96 12171 10976 2 917.520397 459.7678 Protein tyrosine phosphatase type IVA 1 OS=Homo sapiens OX=9606 GN=PTP4A1 PE=1 SV=2 8.75 2489 - 781937 - - - -0.643 - 1.289 0.183 - 146.3 1 2 0 -0.0006 8 0 0 0 4.10E+07 2.09E+07 - - - 1.1581 0.9568 221125_WJC_METTL3_EV_vs_WT_F02.10977.10977.2 0.00241 16-Jul H.IYYGSLEEK.E sp|O43172|PRP4_HUMAN 1 1100.539 4.2 12172 10977 2 1100.538458 551.2768 U4\U6 small nuclear ribonucleoprotein Prp4 OS=Homo sapiens OX=9606 GN=PRPF4 PE=1 SV=2 4.53 2489.2 - 714474 - - - -0.4843 - 1.371 0.365 - 126.1 1 1 0 -0.0005 9 0 0 0 4.29E+07 1.02E+07 - - - 2.6496 0.9963 221125_WJC_METTL3_EV_vs_WT_F02.10980.10980.2 0.0714 18-Dec R.VAIYSPDGVR[166.11].V "sp|Q8NE86|MCU_HUMAN,tr|S4R468|S4R468_HUMAN" 2 1085.5745 0.22 12175 10980 2 1085.575287 543.7945 "Calcium uniporter protein, mitochondrial OS=Homo sapiens OX=9606 GN=MCU PE=1 SV=1" 5.81 2489.6 - 238533 - - - 0.7443 - 1.832 0.098 - 486.6 1 2 0 0.0008 10 0 0 0 1.60E+07 7.16E+07 - - - 1.4545 0.9956 221125_WJC_METTL3_EV_vs_WT_F02.10983.10983.2 0.292 14-Jun R.LNVTPLAR.L "sp|P24752|THIL_HUMAN,tr|A0A5F9ZHJ7|A0A5F9ZHJ7_HUMAN,tr|A0A5F9ZHD4|A0A5F9ZHD4_HUMAN,tr|A0A5F9ZHJ0|A0A5F9ZHJ0_HUMAN,tr|A0A5F9ZHL1|A0A5F9ZHL1_HUMAN,tr|A0A5F9ZI66|A0A5F9ZI66_HUMAN" 6 882.5287 1.4 12176 10983 2 882.529304 442.2716 "Acetyl-CoA acetyltransferase, mitochondrial OS=Homo sapiens OX=9606 GN=ACAT1 PE=1 SV=1" 9.75 2490 - 2.09E+07 - - - 0.6833 - 1.503 0.168 - 128 3 2 0 0.0006 8 0 0 0 6.98E+08 4.99E+08 - - - 1.2974 0.9931 221125_WJC_METTL3_EV_vs_WT_F02.10985.10985.2 0.198 12-Jun K.AIFAGYK.R "sp|P18077|RL35A_HUMAN,tr|F8WB72|F8WB72_HUMAN,tr|C9K025|C9K025_HUMAN,tr|F8WBS5|F8WBS5_HUMAN" 4 768.417 0.96 12178 10985 2 768.417692 385.2158 60S ribosomal protein L35a OS=Homo sapiens OX=9606 GN=RPL35A PE=1 SV=2 8.63 2490.1 - 4.58E+06 - - - 0.8667 - 1.123 0.219 - 145.7 1 2 0 0.0007 7 0 0 0 2.37E+08 2.47E+08 - - - 1.0259 0.9988 221125_WJC_METTL3_EV_vs_WT_F02.10986.10986.2 2.5 16-Aug K.VETFSGVYK[136.11].K "sp|P62081|RS7_HUMAN,tr|A0A2R8Y623|A0A2R8Y623_HUMAN" 2 1036.5321 1.01 12179 10986 2 1036.533181 519.2733 40S ribosomal protein S7 OS=Homo sapiens OX=9606 GN=RPS7 PE=1 SV=1 5.97 2490.1 - 2.41E+06 - - - 1.0796 - 1.937 0.204 - 207.6 1 2 0 0.0011 9 0 0 0 1.91E+08 1.90E+08 - - - 2.4601 0.9968 221125_WJC_METTL3_EV_vs_WT_F02.10987.10987.2 0.0484 16-Oct K.VETFSGVYK.K "sp|P62081|RS7_HUMAN,tr|A0A2R8Y623|A0A2R8Y623_HUMAN" 2 1028.5179 0.98 12180 10987 2 1028.519762 515.2662 40S ribosomal protein S7 OS=Homo sapiens OX=9606 GN=RPS7 PE=1 SV=1 5.97 2490.2 - 1.63E+06 - - - 1.8473 - 1.796 0.174 - 341 1 2 0 0.0019 9 0 0 0 1.85E+08 1.90E+08 - - - 2.0196 0.9986 221125_WJC_METTL3_EV_vs_WT_F02.10991.10991.3 0.000719 Oct-52 K.VQALEEANNDLENK.L sp|P35527|K1C9_HUMAN 1 1585.7584 5.36 12184 10991 3 1585.761436 529.5934 "Keratin, type I cytoskeletal 9 OS=Homo sapiens OX=9606 GN=KRT9 PE=1 SV=3" 4 2490.6 - 467153 - - - 1.9272 - 1.795 0.305 - 87.3 1 2 0 0.0031 14 0 0 0 6.45E+06 1.20E+06 - - - 3.4943 0.934 221125_WJC_METTL3_EV_vs_WT_F02.10996.10996.2 0.0287 16-Sep H.IYYGSLEEK[136.11].E sp|O43172|PRP4_HUMAN 1 1108.5532 4.2 12187 10996 2 1108.553611 555.2839 U4\U6 small nuclear ribonucleoprotein Prp4 OS=Homo sapiens OX=9606 GN=PRPF4 PE=1 SV=2 4.53 2491.3 - 607640 - - - 0.3789 - 1.49 0.282 - 241.2 1 1 0 0.0004 9 0 0 0 4.29E+07 1.02E+07 - - - 2.2774 0.9355 221125_WJC_METTL3_EV_vs_WT_F02.11004.11004.2 0.0424 16-Aug K.IALEDVPEK.Q sp|O43148|MCES_HUMAN 1 1012.5441 1.86 12193 11004 2 1012.552074 507.2793 mRNA cap guanine-N7 methyltransferase OS=Homo sapiens OX=9606 GN=RNMT PE=1 SV=1 4.14 2492.3 - 346307 - - - 7.8979 - 1.578 0.322 - 157.1 1 2 0 0.008 9 0 0 0 2.73E+07 1.47E+07 - - - 2.7365 0.9679 221125_WJC_METTL3_EV_vs_WT_F02.11005.11005.2 0.00101 20-Sep K.LSAMMGAVAEK[136.11].K "sp|Q86U44|MTA70_HUMAN,tr|F5H6D8|F5H6D8_HUMAN,tr|H0YFV6|H0YFV6_HUMAN,tr|B4DTN4|B4DTN4_HUMAN" 4 1114.5606 2.01 12194 11005 2 1114.568307 558.2876 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 6 2492.4 - 162744 - - - 6.913 - 1.768 0.332 - 201.1 1 2 0 0.0077 11 0 0 0 9.97E+06 4.96E+06 - - - 3.0323 0.999 221125_WJC_METTL3_EV_vs_WT_F02.11009.11009.2 0.00128 14-Jun K.YGVTTIVR.V "sp|Q93096|TP4A1_HUMAN,sp|Q12974|TP4A2_HUMAN,tr|E9PRR9|E9PRR9_HUMAN,tr|E9PMY3|E9PMY3_HUMAN,tr|E9PJC0|E9PJC0_HUMAN,tr|E9PML8|E9PML8_HUMAN,tr|A0A0D9SGK2|A0A0D9SGK2_HUMAN" 7 907.5127 0.69 12196 11009 2 907.513718 454.7636 Protein tyrosine phosphatase type IVA 1 OS=Homo sapiens OX=9606 GN=PTP4A1 PE=1 SV=2 8.75 2492.9 - 1.19E+06 - - - 1.103 - 1.514 0.323 - 80.9 1 2 0 0.001 8 0 0 0 1.19E+07 1.73E+07 - - - 2.6772 0.996 221125_WJC_METTL3_EV_vs_WT_F02.11012.11012.2 0.00168 16-Aug K.IALEDVPEK[136.11].Q sp|O43148|MCES_HUMAN 1 1020.5583 1.75 12199 11012 2 1020.562258 511.2864 mRNA cap guanine-N7 methyltransferase OS=Homo sapiens OX=9606 GN=RNMT PE=1 SV=1 4.14 2493.2 - 341825 - - - 3.9008 - 1.738 0.338 - 173.4 1 2 0 0.004 9 0 0 0 2.55E+07 1.46E+07 - - - 3.1353 0.9994 221125_WJC_METTL3_EV_vs_WT_F02.11017.11017.2 2.21 16-Aug R.VLIIGSGGR[166.11].E "sp|P22102|PUR2_HUMAN,tr|F8WD69|F8WD69_HUMAN,tr|C9JKQ7|C9JKQ7_HUMAN,tr|C9JZG2|C9JZG2_HUMAN,tr|C9JTV6|C9JTV6_HUMAN,tr|C9JBJ1|C9JBJ1_HUMAN" 6 880.537 51.72 12202 11017 2 880.537396 441.2758 Trifunctional purine biosynthetic protein adenosine-3 OS=Homo sapiens OX=9606 GN=GART PE=1 SV=1 9.72 2493.9 - 4.90E+06 - - - 0.4827 - 1.708 0.311 - 226.6 1 2 0 0.0004 9 0 0 0 8.56E+09 1.66E+08 - - - 2.8866 0.9931 221125_WJC_METTL3_EV_vs_WT_F02.11019.11019.2 0.467 12-Jul K.LELAQYR.E sp|P25705|ATPA_HUMAN 1 891.4814 1.34 12204 11019 2 891.482284 446.748 "ATP synthase subunit alpha, mitochondrial OS=Homo sapiens OX=9606 GN=ATP5F1A PE=1 SV=1" 6 2494 - 2.00E+06 - - - 0.9725 - 1.432 0.119 - 163.2 1 2 0 0.0009 7 0 0 0 7.63E+08 5.68E+08 - - - 1.0574 0.9885 221125_WJC_METTL3_EV_vs_WT_F02.11021.11021.2 0.0401 12-Aug K.SVLTPLR[166.11].G "sp|O75152|ZC11A_HUMAN,tr|E9PQ61|E9PQ61_HUMAN" 2 794.489 0.89 12206 11021 2 794.489479 398.2518 Zinc finger CCCH domain-containing protein 11A OS=Homo sapiens OX=9606 GN=ZC3H11A PE=1 SV=3 9.47 2494.2 - 982446 - - - 0.6545 - 1.635 0.002 - 247.1 1 2 0 0.0005 7 0 0 0 2.47E+07 2.78E+07 - - - 0.6134 0.999 221125_WJC_METTL3_EV_vs_WT_F02.11023.11023.2 0.0178 14-Oct K.LIQEIVDK[136.11].S "sp|Q06787|FMR1_HUMAN,tr|R9WNI0|R9WNI0_HUMAN,tr|A8MQB8|A8MQB8_HUMAN,tr|A0A087WXI3|A0A087WXI3_HUMAN,tr|G3V0J0|G3V0J0_HUMAN" 5 964.5684 1.71 12208 11023 2 964.569783 483.2915 Synaptic functional regulator FMR1 OS=Homo sapiens OX=9606 GN=FMR1 PE=1 SV=1 4.37 2494.4 - 536730 - - - 1.3851 - 1.595 0.326 - 264 1 2 0 0.0013 8 0 0 0 9.14E+08 5.34E+08 - - - 2.8565 0.9868 221125_WJC_METTL3_EV_vs_WT_F02.11031.11031.2 0.209 14-Jun R.GLGDC[160.03]LVK.L "sp|P05141|ADT2_HUMAN,sp|P12236|ADT3_HUMAN" 2 860.4426 0.8 12214 11031 2 860.443595 431.2286 ADP\ATP translocase 2 OS=Homo sapiens OX=9606 GN=SLC25A5 PE=1 SV=7 5.83 2495.2 - 5.27E+06 - - - 1.1692 - 1.064 0.196 - 78.2 1 2 0 0.001 8 0 0 0 1.94E+08 2.44E+08 - - - 0.6754 0.9418 221125_WJC_METTL3_EV_vs_WT_F02.11033.11033.2 0.898 12-Jun K.SVLTPLR.G "sp|O75152|ZC11A_HUMAN,tr|E9PQ61|E9PQ61_HUMAN" 2 784.4807 0.89 12216 11033 2 784.483319 393.2476 Zinc finger CCCH domain-containing protein 11A OS=Homo sapiens OX=9606 GN=ZC3H11A PE=1 SV=3 9.47 2495.4 - 695463 - - - 3.3525 - 1.234 0.121 - 156 1 2 0 0.0026 7 0 0 0 2.43E+07 2.75E+07 - - - 0.6001 0.9995 221125_WJC_METTL3_EV_vs_WT_F02.11035.11035.2 6.52E-05 16-Nov K.LEAEIATYR.R "sp|P05783|K1C18_HUMAN,tr|F8VZY9|F8VZY9_HUMAN" 2 1064.5502 2.22 12218 11035 2 1064.552942 533.2824 "Keratin, type I cytoskeletal 18 OS=Homo sapiens OX=9606 GN=KRT18 PE=1 SV=2" 4.53 2495.6 - 477375 - - - 2.5523 - 2.304 0.406 - 515.4 1 2 0 0.0027 9 0 0 0 5.57E+07 2.51E+07 - - - 4.4535 0.9991 221125_WJC_METTL3_EV_vs_WT_F02.11038.11038.2 0.0492 14-Aug K.YENELALR.Q "sp|Q99456|K1C12_HUMAN,sp|P19012|K1C15_HUMAN,sp|P13646|K1C13_HUMAN,tr|C9JTG5|C9JTG5_HUMAN,tr|K7EMD9|K7EMD9_HUMAN,tr|K7ERE3|K7ERE3_HUMAN,tr|A0A3B3ITG2|A0A3B3ITG2_HUMAN,tr|A8MT21|A8MT21_HUMAN" 8 1006.5084 2.58 12219 11038 2 1006.509093 504.2615 "Keratin, type I cytoskeletal 12 OS=Homo sapiens OX=9606 GN=KRT12 PE=1 SV=1" 4.53 2496 - 793058 - - - 0.7283 - 1.584 0.294 - 200.8 1 2 0 0.0007 8 0 0 0 8.09E+07 3.14E+07 - - - 2.5995 0.9916 221125_WJC_METTL3_EV_vs_WT_F02.11039.11039.2 0.936 14-Jul K.LLGQFSEK.E sp|P53004|BIEA_HUMAN 1 920.4967 0.67 12220 11039 2 920.497515 461.2556 Biliverdin reductase A OS=Homo sapiens OX=9606 GN=BLVRA PE=1 SV=2 6 2496.1 - 570257 - - - 0.8495 - 1.166 0.187 - 92.1 1 2 0 0.0008 8 0 0 0 1.73E+07 2.58E+07 - - - 0.8851 0.79 221125_WJC_METTL3_EV_vs_WT_F02.11042.11042.2 1.29 18-May K.LYEAGLAYQK[136.11].E "sp|Q15031|SYLM_HUMAN,tr|A0A494C1E0|A0A494C1E0_HUMAN,tr|A0A499FJL2|A0A499FJL2_HUMAN,tr|E9PHM2|E9PHM2_HUMAN" 4 1162.6114 3.65 12223 11042 2 1162.614944 582.313 "Probable leucine--tRNA ligase, mitochondrial OS=Homo sapiens OX=9606 GN=LARS2 PE=1 SV=2" 6 2496.5 - 154891 - - - 3.0698 - 1.067 0.125 - 23.1 23 2 0 0.0036 10 0 0 0 6.21E+06 1.70E+06 - - - -0.4641 0.9659 221125_WJC_METTL3_EV_vs_WT_F02.11047.11047.2 0.182 16-Oct P.EAALSPTFR[166.11].S "sp|Q86U44|MTA70_HUMAN,tr|B4E349|B4E349_HUMAN,tr|F5H6D8|F5H6D8_HUMAN,tr|B4DTN4|B4DTN4_HUMAN" 4 1000.5217 0.02 12226 11047 2 1000.521549 501.2681 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 6.1 2497 - 3.09E+06 - - - -0.1659 - 1.955 0.254 - 314 1 1 0 -0.0002 9 0 0 0 1.82E+07 9.31E+08 - - - 2.8565 0.9997 221125_WJC_METTL3_EV_vs_WT_F02.11048.11048.2 0.00839 16-Nov K.LEAEIATYR[166.11].R "sp|P05783|K1C18_HUMAN,tr|F8VZY9|F8VZY9_HUMAN" 2 1074.5585 2.21 12227 11048 2 1074.558622 538.2865 "Keratin, type I cytoskeletal 18 OS=Homo sapiens OX=9606 GN=KRT18 PE=1 SV=2" 4.53 2497.1 - 559602 - - - 0.1182 - 2.166 0.339 - 450.2 1 2 0 0.0001 9 0 0 0 5.54E+07 2.51E+07 - - - 3.7808 0.9968 221125_WJC_METTL3_EV_vs_WT_F02.11057.11057.2 0.143 16-Jul K.LTGEVVALK[136.11].K "sp|P24941|CDK2_HUMAN,tr|G3V5T9|G3V5T9_HUMAN,tr|E7ESI2|E7ESI2_HUMAN,tr|G3V317|G3V317_HUMAN" 4 936.5735 1.29 12232 11057 2 936.571651 469.294 Cyclin-dependent kinase 2 OS=Homo sapiens OX=9606 GN=CDK2 PE=1 SV=2 6 2498.3 - 351889 - - - -2.0095 - 1.437 0.265 - 91.3 1 2 0 -0.0019 9 0 0 0 1.09E+07 8.46E+06 - - - 2.0466 0.998 221125_WJC_METTL3_EV_vs_WT_F02.11070.11070.2 0.157 14-Sep K.LAQFDYGR[166.11].K "sp|Q5T2N8|ATD3C_HUMAN,sp|Q5T9A4|ATD3B_HUMAN,sp|Q9NVI7|ATD3A_HUMAN,tr|Q5SV16|Q5SV16_HUMAN" 4 978.4799 1.17 12238 11070 2 978.480676 490.2472 ATPase family AAA domain-containing protein 3C OS=Homo sapiens OX=9606 GN=ATAD3C PE=2 SV=2 5.84 2499.9 - 1.67E+06 - - - 0.8442 - 1.733 0.17 - 327.9 1 2 0 0.0008 8 0 0 0 7.37E+07 6.28E+07 - - - 1.9547 0.9944 221125_WJC_METTL3_EV_vs_WT_F02.11071.11071.2 0.274 14-Aug R.SNPYYIVK.Q sp|Q9UQE7|SMC3_HUMAN 1 982.5124 0.61 12239 11071 2 982.513504 492.2635 Structural maintenance of chromosomes protein 3 OS=Homo sapiens OX=9606 GN=SMC3 PE=1 SV=2 8.22 2500 - 963385 - - - 1.141 - 1.164 0.24 - 151 1 2 0 0.0011 8 0 0 0 4.31E+07 7.05E+07 - - - 1.2713 0.7787 221125_WJC_METTL3_EV_vs_WT_F02.11075.11075.2 0.0144 18-Jun R.LLEGEDAHLT.Q "sp|Q04695|K1C17_HUMAN,tr|A0A3B3IS58|A0A3B3IS58_HUMAN,tr|F5GWP8|F5GWP8_HUMAN" 3 1096.5401 - 12241 11075 2 1096.54238 549.2773 "Keratin, type I cytoskeletal 17 OS=Homo sapiens OX=9606 GN=KRT17 PE=1 SV=2" 4.13 2500.5 - 516052 - - - 2.1212 - 1.151 0.326 - 52.2 1 1 0 0.0023 10 0 0 0 - - - - - 1.8406 0.9977 221125_WJC_METTL3_EV_vs_WT_F02.11078.11078.2 0.118 14-Jul R.MGGNQLFR[166.11].L "sp|Q86SF2|GALT7_HUMAN,tr|H0YAK0|H0YAK0_HUMAN,tr|H0YAH3|H0YAH3_HUMAN" 3 931.4573 0.9 12242 11078 2 931.457429 466.7359 N-acetylgalactosaminyltransferase 7 OS=Homo sapiens OX=9606 GN=GALNT7 PE=1 SV=1 9.5 2500.9 - 656928 - - - 0.0945 - 1.246 0.269 - 118.4 1 2 0 0.0001 8 0 0 0 4.23E+07 4.72E+07 - - - 1.6911 0.9992 221125_WJC_METTL3_EV_vs_WT_F02.11080.11080.2 0.00228 14-Jul K.LAQFDYGR.K "sp|Q5T2N8|ATD3C_HUMAN,sp|Q5T9A4|ATD3B_HUMAN,sp|Q9NVI7|ATD3A_HUMAN,tr|Q5SV16|Q5SV16_HUMAN" 4 968.4716 1.17 12243 11080 2 968.472102 485.2431 ATPase family AAA domain-containing protein 3C OS=Homo sapiens OX=9606 GN=ATAD3C PE=2 SV=2 5.84 2501.1 - 4.17E+06 - - - 0.539 - 1.476 0.329 - 124.8 1 2 0 0.0005 8 0 0 0 7.36E+07 6.28E+07 - - - 2.645 0.7673 221125_WJC_METTL3_EV_vs_WT_F02.11094.11094.2 0.491 12-Jun L.VLPPNWK[136.11].T "sp|Q9BYW2|SETD2_HUMAN,sp|P62277|RS13_HUMAN" 2 860.5 1.28 12253 11094 2 860.499614 431.2573 Histone-lysine N-methyltransferase SETD2 OS=Homo sapiens OX=9606 GN=SETD2 PE=1 SV=3 8.72 2502.7 - 2.20E+06 - - - -0.4184 - 1.075 0.249 - 112.7 1 1 0 -0.0004 7 0 0 0 1.66E+08 1.30E+08 - - - 1.1092 0.9957 221125_WJC_METTL3_EV_vs_WT_F02.11095.11095.2 0.0412 12-May R.EMFNYAR[166.11].D "sp|P62333|PRS10_HUMAN,tr|H0YJX2|H0YJX2_HUMAN,tr|A0A087X2I1|A0A087X2I1_HUMAN,tr|H0YJC0|H0YJC0_HUMAN,tr|H0YJS8|H0YJS8_HUMAN" 5 939.4148 0.64 12254 11095 2 939.414234 470.7147 26S proteasome regulatory subunit 10B OS=Homo sapiens OX=9606 GN=PSMC6 PE=1 SV=1 6.1 2502.8 - 541163 - - - -0.61 - 1.126 0.249 - 97.7 1 2 0 -0.0006 7 0 0 0 1.23E+07 1.91E+07 - - - 1.256 0.9529 221125_WJC_METTL3_EV_vs_WT_F02.11100.11100.2 0.257 18-May R.LYDVPANSMR[166.11].L "sp|O43684|BUB3_HUMAN,tr|J3QT28|J3QT28_HUMAN,tr|J3QSX4|J3QSX4_HUMAN" 3 1174.568 0.62 12257 11100 2 1174.563736 588.2913 Mitotic checkpoint protein BUB3 OS=Homo sapiens OX=9606 GN=BUB3 PE=1 SV=1 5.84 2503.5 - 210800 - - - -3.6422 - 1.23 0.171 - 85.9 1 2 0 -0.0043 10 0 0 0 3.16E+07 5.14E+07 - - - 0.8805 0.9995 221125_WJC_METTL3_EV_vs_WT_F02.11101.11101.2 0.0116 22-Sep R.ALEEANTELEVK.L "sp|Q04695|K1C17_HUMAN,tr|K7EPJ9|K7EPJ9_HUMAN" 2 1344.6773 3.43 12258 11101 2 1344.678994 673.3459 "Keratin, type I cytoskeletal 17 OS=Homo sapiens OX=9606 GN=KRT17 PE=1 SV=2" 4.09 2503.6 - 187700 - - - 1.2776 - 1.954 0.355 - 125.9 1 2 0 0.0017 12 0 0 0 7.18E+06 2.09E+06 - - - 3.4251 0.9991 221125_WJC_METTL3_EV_vs_WT_F02.11109.11109.2 0.0578 14-Sep K.LIQEIVDK.S "sp|Q06787|FMR1_HUMAN,tr|R9WNI0|R9WNI0_HUMAN,tr|A8MQB8|A8MQB8_HUMAN,tr|A0A087WXI3|A0A087WXI3_HUMAN,tr|G3V0J0|G3V0J0_HUMAN" 5 956.5542 1.74 12262 11109 2 956.554617 479.2844 Synaptic functional regulator FMR1 OS=Homo sapiens OX=9606 GN=FMR1 PE=1 SV=1 4.37 2504.6 - 2.24E+07 - - - 0.3868 - 1.751 0.239 - 228 1 2 0 0.0004 8 0 0 0 9.29E+08 5.34E+08 - - - 2.4956 0.9954 221125_WJC_METTL3_EV_vs_WT_F02.11112.11112.2 0.0738 18-Jul R.LILEPTQAAK[136.11].L sp|Q9NU22|MDN1_HUMAN 1 1090.6478 0.78 12265 11112 2 1090.645448 546.3312 Midasin OS=Homo sapiens OX=9606 GN=MDN1 PE=1 SV=2 6 2504.9 - 420269 - - - -2.1198 - 1.314 0.271 - 84.2 1 2 0 -0.0023 10 0 0 0 1.26E+07 1.62E+07 - - - 1.8041 0.8501 221125_WJC_METTL3_EV_vs_WT_F02.11117.11117.2 0.0172 16-Jun Y.YTSVTPVLR[166.11].G "sp|P26599|PTBP1_HUMAN,tr|A0A6Q8PEX4|A0A6Q8PEX4_HUMAN,tr|A0A0U1RRM4|A0A0U1RRM4_HUMAN,tr|A6NLN1|A6NLN1_HUMAN,tr|K7EKJ7|K7EKJ7_HUMAN,tr|K7ES59|K7ES59_HUMAN,tr|A0A7I2V4H6|A0A7I2V4H6_HUMAN,tr|A0A7I2V621|A0A7I2V621_HUMAN" 8 1044.5843 0.57 12268 11117 2 1044.583661 523.2994 Polypyrimidine tract-binding protein 1 OS=Homo sapiens OX=9606 GN=PTBP1 PE=1 SV=1 8.75 2505.6 - 739205 - - - -0.627 - 1.318 0.23 - 70.5 1 1 0 -0.0007 9 0 0 0 2.76E+07 4.85E+07 - - - 1.5384 0.9996 221125_WJC_METTL3_EV_vs_WT_F02.11120.11120.2 0.000522 18-Oct R.LYDVPANSMR.L "sp|O43684|BUB3_HUMAN,tr|J3QT28|J3QT28_HUMAN,tr|J3QSX4|J3QSX4_HUMAN" 3 1164.5597 0.7 12271 11120 2 1164.56076 583.2871 Mitotic checkpoint protein BUB3 OS=Homo sapiens OX=9606 GN=BUB3 PE=1 SV=1 5.84 2505.9 - 307702 - - - 0.8724 - 1.806 0.385 - 257 1 2 0 0.001 10 0 0 0 3.59E+07 5.16E+07 - - - 3.5343 0.9964 221125_WJC_METTL3_EV_vs_WT_F02.11126.11126.2 0.0977 12-May R.LEYDDLR.R sp|P15924|DESP_HUMAN 1 922.4396 4.3 12274 11126 2 922.439829 462.2271 Desmoplakin OS=Homo sapiens OX=9606 GN=DSP PE=1 SV=3 4.03 2506.7 - 5.01E+06 - - - 0.2352 - 1.258 0.216 - 100.8 1 2 0 0.0002 7 0 0 0 1.38E+08 3.22E+07 - - - 1.3636 0.7777 221125_WJC_METTL3_EV_vs_WT_F02.11127.11127.2 0.245 12-Jun E.AQLLEMR.L "sp|Q9NQT8|KI13B_HUMAN,sp|Q96P63|SPB12_HUMAN" 2 859.4586 1.59 12275 11127 2 859.459572 430.7366 Kinesin-like protein KIF13B OS=Homo sapiens OX=9606 GN=KIF13B PE=1 SV=2 6.05 2506.7 - 2.54E+06 - - - 1.1624 - 1.389 0.179 - 187.3 1 1 0 0.001 7 0 0 0 1.53E+08 9.66E+07 - - - 1.4039 0.9868 221125_WJC_METTL3_EV_vs_WT_F02.11128.11128.2 0.00021 16-Sep Y.YTSVTPVLR.G "sp|P26599|PTBP1_HUMAN,tr|A0A6Q8PEX4|A0A6Q8PEX4_HUMAN,tr|A0A0U1RRM4|A0A0U1RRM4_HUMAN,tr|A6NLN1|A6NLN1_HUMAN,tr|K7EKJ7|K7EKJ7_HUMAN,tr|K7ES59|K7ES59_HUMAN,tr|A0A7I2V4H6|A0A7I2V4H6_HUMAN,tr|A0A7I2V621|A0A7I2V621_HUMAN" 8 1034.576 0.6 12276 11128 2 1034.577093 518.2953 Polypyrimidine tract-binding protein 1 OS=Homo sapiens OX=9606 GN=PTBP1 PE=1 SV=1 8.75 2506.9 - 802848 - - - 1.012 - 1.854 0.474 - 342.3 1 1 0 0.001 9 0 0 0 2.76E+07 4.59E+07 - - - 4.3276 0.9958 221125_WJC_METTL3_EV_vs_WT_F02.11141.11141.2 0.273 14-Sep K.MLEIDPQK[136.11].V "sp|P24752|THIL_HUMAN,tr|A0A5F9ZHD4|A0A5F9ZHD4_HUMAN,tr|A0A5F9ZHJ0|A0A5F9ZHJ0_HUMAN,tr|A0A5F9ZHL1|A0A5F9ZHL1_HUMAN,tr|A0A5F9ZI66|A0A5F9ZI66_HUMAN" 5 980.5092 0.95 12285 11141 2 980.509578 491.2619 "Acetyl-CoA acetyltransferase, mitochondrial OS=Homo sapiens OX=9606 GN=ACAT1 PE=1 SV=1" 4.37 2508.4 - 651285 - - - 0.3672 - 1.37 0.172 - 185.9 1 2 0 0.0004 8 0 0 0 3.33E+07 3.50E+07 - - - 1.2607 0.9983 221125_WJC_METTL3_EV_vs_WT_F02.11145.11145.2 0.00113 20-Sep K.LVMEEAPESYK[136.11].N sp|Q9Y3I0|RTCB_HUMAN 1 1302.6257 1.34 12287 11145 2 1302.630075 652.3201 RNA-splicing ligase RtcB homolog OS=Homo sapiens OX=9606 GN=RTCB PE=1 SV=1 4.25 2509 - 253690 - - - 3.3555 - 1.657 0.437 - 217.6 1 2 0 0.0044 11 0 0 0 8.56E+07 6.41E+07 - - - 3.6335 0.9584 221125_WJC_METTL3_EV_vs_WT_F02.11153.11153.2 0.065 14-Jul K.YVPLADVK.S "sp|P42167|LAP2B_HUMAN,tr|G5E972|G5E972_HUMAN,tr|H0YJH7|H0YJH7_HUMAN" 3 903.5066 0.97 12292 11153 2 903.51065 452.7606 "Lamina-associated polypeptide 2, isoforms beta\gamma OS=Homo sapiens OX=9606 GN=TMPO PE=1 SV=2" 5.83 2509.8 - 9.03E+06 - - - 4.5168 - 1.114 0.283 - 180.2 1 2 0 0.0041 8 0 0 0 2.97E+08 3.06E+08 - - - 1.4556 0.9897 221125_WJC_METTL3_EV_vs_WT_F02.11155.11155.2 3.29 14-Aug K.LLEATELK[136.11].G "sp|Q13813|SPTN1_HUMAN,tr|A0A0D9SF54|A0A0D9SF54_HUMAN,tr|A0A0D9SGF6|A0A0D9SGF6_HUMAN" 3 923.5419 1.59 12294 11155 2 923.54275 462.7782 "Spectrin alpha chain, non-erythrocytic 1 OS=Homo sapiens OX=9606 GN=SPTAN1 PE=1 SV=3" 4.53 2510 - 2.14E+06 - - - 0.9225 - 1.358 0.108 - 133 1 2 0 0.0009 8 0 0 0 8.21E+07 5.16E+07 - - - 0.7613 0.9875 221125_WJC_METTL3_EV_vs_WT_F02.11160.11160.2 0.0679 12-Jul R.FQTLISK.M "sp|Q16526|CRY1_HUMAN,sp|Q6ZWB6|KCTD8_HUMAN,tr|H0Y9S2|H0Y9S2_HUMAN" 3 835.4804 1.09 12297 11160 2 835.483159 418.7475 Cryptochrome-1 OS=Homo sapiens OX=9606 GN=CRY1 PE=1 SV=1 8.75 2510.6 - 987778 - - - 3.3574 - 1.373 0.23 - 149.4 1 2 0 0.0028 7 0 0 0 4.80E+07 4.40E+07 - - - 1.7433 0.9995 221125_WJC_METTL3_EV_vs_WT_F02.11161.11161.2 8.28E-07 20-Oct K.LVMEEAPESYK.N sp|Q9Y3I0|RTCB_HUMAN 1 1294.6115 1.34 12298 11161 2 1294.61555 648.313 RNA-splicing ligase RtcB homolog OS=Homo sapiens OX=9606 GN=RTCB PE=1 SV=1 4.25 2510.7 - 841755 - - - 3.1253 - 1.959 0.586 - 309.8 1 2 0 0.004 11 0 0 0 8.56E+07 6.41E+07 - - - 5.187 0.9991 221125_WJC_METTL3_EV_vs_WT_F02.11162.11162.2 0.0106 18-Aug R.LVGEPVLGAK[136.11].M sp|Q15477|SKIV2_HUMAN 1 989.6001 1.07 12299 11162 2 989.600608 495.8073 Helicase SKI2W OS=Homo sapiens OX=9606 GN=SKIV2L PE=1 SV=3 6 2510.8 - 541861 - - - 0.5315 - 1.717 0.27 - 130.6 1 2 0 0.0005 10 0 0 0 3.99E+07 3.72E+07 - - - 2.544 0.9973 221125_WJC_METTL3_EV_vs_WT_F02.11163.11163.2 0.00694 16-Jun R.AMMYSGELK.F "sp|P12268|IMDH2_HUMAN,tr|A0A7I2YQK5|A0A7I2YQK5_HUMAN,tr|H0Y4R1|H0Y4R1_HUMAN,tr|A0A7I2V2T3|A0A7I2V2T3_HUMAN,tr|E7ETK5|E7ETK5_HUMAN" 5 1028.4671 0.81 12300 11163 2 1028.468244 515.2408 Inosine-5'-monophosphate dehydrogenase 2 OS=Homo sapiens OX=9606 GN=IMPDH2 PE=1 SV=2 6.05 2510.9 - 400382 - - - 1.123 - 1.287 0.278 - 128.1 1 2 0 0.0012 9 0 0 0 3.92E+07 4.83E+07 - - - 1.8239 0.8294 221125_WJC_METTL3_EV_vs_WT_F02.11167.11167.2 2.22 18-Jun K.VDPEALQVFK.E "sp|Q9Y576|ASB1_HUMAN,tr|B9A047|B9A047_HUMAN" 2 1144.6128 48 12302 11167 2 1144.614083 573.3137 Ankyrin repeat and SOCS box protein 1 OS=Homo sapiens OX=9606 GN=ASB1 PE=1 SV=1 4.37 2511.5 - 332659 - - - 1.0991 - 0.992 0.048 - 34.9 10 2 0 0.0013 10 0 0 0 1.79E+07 3.72E+05 - - - -1.074 0.9544 221125_WJC_METTL3_EV_vs_WT_F02.11173.11173.2 0.0284 16-Aug G.TTIAGVVYK.D "sp|Q99436|PSB7_HUMAN,tr|Q5TBG5|Q5TBG5_HUMAN" 2 950.5437 0.18 12306 11173 2 950.544726 476.2791 Proteasome subunit beta type-7 OS=Homo sapiens OX=9606 GN=PSMB7 PE=1 SV=1 8.26 2512.1 - 1.41E+06 - - - 1.0973 - 1.695 0.314 - 237.5 1 1 0 0.001 9 0 0 0 2.98E+07 1.65E+08 - - - 2.8865 0.9993 221125_WJC_METTL3_EV_vs_WT_F02.11175.11175.2 0.000303 16-Aug R.AMMYSGELK[136.11].F "sp|P12268|IMDH2_HUMAN,tr|A0A7I2YQK5|A0A7I2YQK5_HUMAN,tr|H0Y4R1|H0Y4R1_HUMAN,tr|A0A7I2V2T3|A0A7I2V2T3_HUMAN,tr|E7ETK5|E7ETK5_HUMAN" 5 1036.4813 0.81 12308 11175 2 1036.482461 519.2479 Inosine-5'-monophosphate dehydrogenase 2 OS=Homo sapiens OX=9606 GN=IMPDH2 PE=1 SV=2 6.05 2512.3 - 1.31E+06 - - - 1.1307 - 1.451 0.4 - 232.6 1 2 0 0.0012 9 0 0 0 3.91E+07 4.83E+07 - - - 3.072 0.9984 221125_WJC_METTL3_EV_vs_WT_F02.11176.11176.2 0.00172 14-Jul K.IYEEAWTK[136.11].Y "sp|Q9BXJ9|NAA15_HUMAN,tr|A0A0B4J1W3|A0A0B4J1W3_HUMAN" 2 1046.5164 0.24 12309 11176 2 1046.518022 524.2655 "N-alpha-acetyltransferase 15, NatA auxiliary subunit OS=Homo sapiens OX=9606 GN=NAA15 PE=1 SV=1" 4.53 2512.3 - 1.04E+06 - - - 1.5384 - 1.3 0.354 - 122.4 1 2 0 0.0016 8 0 0 0 1.14E+07 4.78E+07 - - - 2.4464 0.9988 221125_WJC_METTL3_EV_vs_WT_F02.11177.11177.2 0.00755 18-Jul R.LVGEPVLGAK.M sp|Q15477|SKIV2_HUMAN 1 981.5859 1.07 12310 11177 2 981.587 491.8002 Helicase SKI2W OS=Homo sapiens OX=9606 GN=SKIV2L PE=1 SV=3 6 2512.4 - 880165 - - - 1.139 - 1.531 0.331 - 68.3 2 2 0 0.0011 10 0 0 0 3.99E+07 3.72E+07 - - - 2.5398 0.9995 221125_WJC_METTL3_EV_vs_WT_F02.11182.11182.2 0.00422 14-Sep K.TTDGYLLR[166.11].L "sp|P61247|RS3A_HUMAN,tr|H0Y8L7|H0Y8L7_HUMAN,tr|D6R9B6|D6R9B6_HUMAN,tr|H0Y9Y4|H0Y9Y4_HUMAN,tr|D6RED7|D6RED7_HUMAN,tr|D6RAS7|D6RAS7_HUMAN,tr|D6RB09|D6RB09_HUMAN,tr|E9PFI5|E9PFI5_HUMAN,tr|D6RAT0|D6RAT0_HUMAN,tr|D6RG13|D6RG13_HUMAN" 10 947.4952 0.97 12313 11182 2 947.496571 474.7549 40S ribosomal protein S3a OS=Homo sapiens OX=9606 GN=RPS3A PE=1 SV=2 5.5 2513 - 2.51E+06 - - - 1.4829 - 1.757 0.374 - 422.8 1 2 0 0.0014 8 0 0 0 3.24E+08 3.33E+08 - - - 3.5027 0.9983 221125_WJC_METTL3_EV_vs_WT_F02.11183.11183.2 0.0226 14-Aug K.TTDGYLLR.L "sp|P61247|RS3A_HUMAN,tr|H0Y8L7|H0Y8L7_HUMAN,tr|D6R9B6|D6R9B6_HUMAN,tr|H0Y9Y4|H0Y9Y4_HUMAN,tr|D6RED7|D6RED7_HUMAN,tr|D6RAS7|D6RAS7_HUMAN,tr|D6RB09|D6RB09_HUMAN,tr|E9PFI5|E9PFI5_HUMAN,tr|D6RAT0|D6RAT0_HUMAN,tr|D6RG13|D6RG13_HUMAN" 10 937.4869 0.98 12314 11183 2 937.488458 469.7507 40S ribosomal protein S3a OS=Homo sapiens OX=9606 GN=RPS3A PE=1 SV=2 5.5 2513.1 - 1.83E+06 - - - 1.6662 - 1.492 0.301 - 301.2 1 2 0 0.0016 8 0 0 0 3.25E+08 3.33E+08 - - - 2.4704 0.857 221125_WJC_METTL3_EV_vs_WT_F02.11185.11185.2 2.04 16-Apr R.KNEELGDEK[136.11].R sp|Q5VUJ6|LRCH2_HUMAN 1 1068.5179 - 12316 11185 2 1068.517878 535.2662 Leucine-rich repeat and calponin homology domain-containing protein 2 OS=Homo sapiens OX=9606 GN=LRCH2 PE=1 SV=2 4.41 2513.3 - 302884 - - - 0.0094 - 0.971 0.033 - 56.6 6 2 0 0 9 0 0 0 - - - - - -1.148 0.9996 221125_WJC_METTL3_EV_vs_WT_F02.11186.11186.2 0.000994 20-Jul R.VLAETPDSFEK.H "sp|Q99567|NUP88_HUMAN,tr|J3KMX1|J3KMX1_HUMAN" 2 1234.6081 2.22 12317 11186 2 1234.607998 618.3113 Nuclear pore complex protein Nup88 OS=Homo sapiens OX=9606 GN=NUP88 PE=1 SV=2 4.14 2513.4 - 170524 - - - -0.1102 - 1.527 0.405 - 69.9 1 2 0 -0.0001 11 0 0 0 1.06E+07 4.78E+06 - - - 3.1774 0.9757 221125_WJC_METTL3_EV_vs_WT_F02.11189.11189.2 0.00177 12-Jun R.VVDLMAH.M "sp|P04406|G3P_HUMAN,tr|E7EUT5|E7EUT5_HUMAN" 2 783.3949 - 12318 11189 2 783.394604 392.7047 Glyceraldehyde-3-phosphate dehydrogenase OS=Homo sapiens OX=9606 GN=GAPDH PE=1 SV=3 5.08 2513.8 - 2.03E+06 - - - -0.3906 - 1.372 0.431 - 139.5 1 1 0 -0.0003 7 0 0 0 - - - - - 3.2264 0.9966 221125_WJC_METTL3_EV_vs_WT_F02.11191.11191.2 0.0375 14-Sep K.LLDEDEIR.G "sp|O43719|HTSF1_HUMAN,tr|Q5H919|Q5H919_HUMAN,tr|Q5H918|Q5H918_HUMAN" 3 1001.5029 0.46 12320 11191 2 1001.501121 501.7587 HIV Tat-specific factor 1 OS=Homo sapiens OX=9606 GN=HTATSF1 PE=1 SV=1 3.92 2514 - 1.66E+06 - - - -1.8163 - 1.524 0.211 - 235.1 1 2 0 -0.0018 8 0 0 0 2.46E+07 5.38E+07 - - - 1.8696 0.9973 221125_WJC_METTL3_EV_vs_WT_F02.11198.11198.2 0.0233 18-Oct K.LGADYGLDAR[166.11].L sp|Q8IYB8|SUV3_HUMAN 1 1059.5224 1.61 12322 11198 2 1059.524879 530.7685 "ATP-dependent RNA helicase SUPV3L1, mitochondrial OS=Homo sapiens OX=9606 GN=SUPV3L1 PE=1 SV=1" 4.21 2515 - 254589 - - - 2.2982 - 2.131 0.169 - 328.3 1 2 0 0.0024 10 0 0 0 9.51E+06 5.92E+06 - - - 2.4003 0.9989 221125_WJC_METTL3_EV_vs_WT_F02.11199.11199.2 0.00315 20-Aug R.VLAETPDSFEK[136.11].H "sp|Q99567|NUP88_HUMAN,tr|J3KMX1|J3KMX1_HUMAN" 2 1242.6223 2.22 12323 11199 2 1242.62638 622.3184 Nuclear pore complex protein Nup88 OS=Homo sapiens OX=9606 GN=NUP88 PE=1 SV=2 4.14 2515.1 - 112078 - - - 3.256 - 1.744 0.484 - 173 1 2 0 0.004 11 0 0 0 1.06E+07 4.78E+06 - - - 4.1192 0.9982 221125_WJC_METTL3_EV_vs_WT_F02.11204.11204.2 1.28 14-Aug R.ILLAVNGK[136.11].V sp|O15173|PGRC2_HUMAN 1 834.5418 1.32 12326 11204 2 834.541592 418.2782 Membrane-associated progesterone receptor component 2 OS=Homo sapiens OX=9606 GN=PGRMC2 PE=1 SV=1 8.75 2515.7 - 2.63E+06 - - - -0.296 - 1.521 0.212 - 166.6 1 2 0 -0.0002 8 0 0 0 1.81E+08 1.38E+08 - - - 1.8715 0.9853 221125_WJC_METTL3_EV_vs_WT_F02.11207.11207.2 3.97 14-Aug R.QLLAPVVK[136.11].E "sp|Q13576|IQGA2_HUMAN,sp|P46940|IQGA1_HUMAN,tr|H0YLE8|H0YLE8_HUMAN,tr|F5H7S7|F5H7S7_HUMAN,tr|E7EWC2|E7EWC2_HUMAN,tr|A0A0J9YXZ5|A0A0J9YXZ5_HUMAN" 6 874.5731 0.82 12329 11207 2 874.57388 438.2938 Ras GTPase-activating-like protein IQGAP2 OS=Homo sapiens OX=9606 GN=IQGAP2 PE=1 SV=4 8.75 2516 - 375597 - - - 0.8473 - 1.504 0.031 - 164.8 1 2 0 0.0007 8 0 0 0 8.87E+07 1.09E+08 - - - 0.5006 0.9994 221125_WJC_METTL3_EV_vs_WT_F02.11213.11213.2 0.0713 12-Jul K.LTGMAFR[166.11].V "sp|O14556|G3PT_HUMAN,sp|P04406|G3P_HUMAN,tr|E7EUT5|E7EUT5_HUMAN" 3 804.4192 0.9 12333 11213 2 804.419186 403.2169 "Glyceraldehyde-3-phosphate dehydrogenase, testis-specific OS=Homo sapiens OX=9606 GN=GAPDHS PE=1 SV=2" 9.75 2516.6 - 1.74E+06 - - - 0.0273 - 1.698 0.296 - 173.4 1 2 0 0 7 0 0 0 3.18E+09 3.56E+09 - - - 2.9048 0.9979 221125_WJC_METTL3_EV_vs_WT_F02.11217.11217.2 2.03 20-Sep R.AVLLGPPGAGK[136.11].G "sp|P54819|KAD2_HUMAN,tr|A0A5F9ZHP2|A0A5F9ZHP2_HUMAN,tr|G3V213|G3V213_HUMAN,tr|F8VY04|F8VY04_HUMAN,tr|F8W1A4|F8W1A4_HUMAN,tr|A0A5K1VW67|A0A5K1VW67_HUMAN,tr|F8VPP1|F8VPP1_HUMAN,tr|F8VZG5|F8VZG5_HUMAN" 8 986.6004 1.34 12335 11217 2 986.600511 494.3075 "Adenylate kinase 2, mitochondrial OS=Homo sapiens OX=9606 GN=AK2 PE=1 SV=2" 8.8 2517.1 - 829003 - - - 0.0963 - 1.729 0.166 - 202.2 1 2 0 0.0001 11 0 0 0 8.20E+07 6.13E+07 - - - 1.7483 0.9972 221125_WJC_METTL3_EV_vs_WT_F02.11219.11219.2 0.701 14-Aug R.ILLAVNGK.V sp|O15173|PGRC2_HUMAN 1 826.5276 1.32 12337 11219 2 826.528082 414.2711 Membrane-associated progesterone receptor component 2 OS=Homo sapiens OX=9606 GN=PGRMC2 PE=1 SV=1 8.75 2517.2 - 4.36E+06 - - - 0.536 - 1.568 0.163 - 158 1 2 0 0.0004 8 0 0 0 1.82E+08 1.38E+08 - - - 1.6014 0.9993 221125_WJC_METTL3_EV_vs_WT_F02.11222.11222.2 0.0087 16-Aug R.VFYTGQVVK[136.11].V "sp|Q14690|RRP5_HUMAN,tr|A0A3B3IUD7|A0A3B3IUD7_HUMAN" 2 1047.5844 0.69 12338 11222 2 1047.585179 524.7995 Protein RRP5 homolog OS=Homo sapiens OX=9606 GN=PDCD11 PE=1 SV=3 8.56 2517.6 - 1.16E+06 - - - 0.7131 - 1.369 0.383 - 160.5 1 2 0 0.0007 9 0 0 0 3.30E+07 4.79E+07 - - - 2.7783 0.9994 221125_WJC_METTL3_EV_vs_WT_F02.11223.11223.2 0.0544 16-Jul R.ISQLQAELR.R "sp|O94766|B3GA3_HUMAN,tr|G3V150|G3V150_HUMAN,tr|E9PNA1|E9PNA1_HUMAN" 3 1056.5928 1.25 12339 11223 2 1056.593148 529.3037 Galactosylgalactosylxylosylprotein 3-beta-glucuronosyltransferase 3 OS=Homo sapiens OX=9606 GN=B3GAT3 PE=1 SV=2 6 2517.8 - 248968 - - - 0.3691 - 1.664 0.316 - 149.9 1 2 0 0.0004 9 0 0 0 3.52E+07 2.82E+07 - - - 2.8481 0.9995 221125_WJC_METTL3_EV_vs_WT_F02.11225.11225.2 0.0176 16-Oct R.ISQLQAELR[166.11].R "sp|O94766|B3GA3_HUMAN,tr|G3V150|G3V150_HUMAN,tr|E9PNA1|E9PNA1_HUMAN" 3 1066.601 2.2 12341 11225 2 1066.602251 534.3078 Galactosylgalactosylxylosylprotein 3-beta-glucuronosyltransferase 3 OS=Homo sapiens OX=9606 GN=B3GAT3 PE=1 SV=2 6 2517.9 - 379555 - - - 1.1466 - 2.051 0.312 - 359 1 2 0 0.0012 9 0 0 0 6.56E+07 2.98E+07 - - - 3.4232 0.9966 221125_WJC_METTL3_EV_vs_WT_F02.11228.11228.2 0.524 20-Sep R.AVLLGPPGAGK.G "sp|P54819|KAD2_HUMAN,tr|A0A5F9ZHP2|A0A5F9ZHP2_HUMAN,tr|G3V213|G3V213_HUMAN,tr|F8VY04|F8VY04_HUMAN,tr|F8W1A4|F8W1A4_HUMAN,tr|A0A5K1VW67|A0A5K1VW67_HUMAN,tr|F8VPP1|F8VPP1_HUMAN,tr|F8VZG5|F8VZG5_HUMAN" 8 978.5862 1.42 12342 11228 2 978.586317 490.3004 "Adenylate kinase 2, mitochondrial OS=Homo sapiens OX=9606 GN=AK2 PE=1 SV=2" 8.8 2518.3 - 1.05E+06 - - - 0.1032 - 1.702 0.123 - 186.7 1 2 0 0.0001 11 0 0 0 8.71E+07 6.13E+07 - - - 1.3881 0.9998 221125_WJC_METTL3_EV_vs_WT_F02.11233.11233.2 0.000838 18-Sep K.LLVGSEDYGR.D "sp|Q13813|SPTN1_HUMAN,tr|A0A0D9SF54|A0A0D9SF54_HUMAN,tr|A0A0D9SGF6|A0A0D9SGF6_HUMAN" 3 1107.556 1.25 12345 11233 2 1107.556958 554.7853 "Spectrin alpha chain, non-erythrocytic 1 OS=Homo sapiens OX=9606 GN=SPTAN1 PE=1 SV=3" 4.37 2519 - 327432 - - - 0.8307 - 1.817 0.477 - 238.7 1 2 0 0.0009 10 0 0 0 9.05E+07 7.25E+07 - - - 4.2308 0.9997 221125_WJC_METTL3_EV_vs_WT_F02.11234.11234.2 0.0566 18-Nov K.LLVGSEDYGR[166.11].D "sp|Q13813|SPTN1_HUMAN,tr|A0A0D9SF54|A0A0D9SF54_HUMAN,tr|A0A0D9SGF6|A0A0D9SGF6_HUMAN" 3 1117.5643 1.27 12346 11234 2 1117.565227 559.7894 "Spectrin alpha chain, non-erythrocytic 1 OS=Homo sapiens OX=9606 GN=SPTAN1 PE=1 SV=3" 4.37 2519.1 - 394152 - - - 0.8223 - 1.974 0.404 - 365.9 1 2 0 0.0009 10 0 0 0 8.93E+07 7.04E+07 - - - 3.9229 0.9997 221125_WJC_METTL3_EV_vs_WT_F02.11236.11236.2 0.00167 14-Sep K.VEIATLTR[166.11].E "sp|P25789|PSA4_HUMAN,tr|H0YL69|H0YL69_HUMAN,tr|H0YN18|H0YN18_HUMAN,tr|H0YMZ1|H0YMZ1_HUMAN" 4 911.5316 0.69 12347 11236 2 911.530895 456.7731 Proteasome subunit alpha type-4 OS=Homo sapiens OX=9606 GN=PSMA4 PE=1 SV=1 5.97 2519.3 - 7.63E+06 - - - -0.7208 - 2 0.349 - 414.3 1 2 0 -0.0007 8 0 0 0 4.21E+08 6.07E+08 - - - 3.709 0.9996 221125_WJC_METTL3_EV_vs_WT_F02.11238.11238.2 0.398 18-Aug K.DVLVGADSVR.A "sp|O43760|SNG2_HUMAN,tr|K7EJ35|K7EJ35_HUMAN" 2 1029.5455 8.52 12348 11238 2 1029.545023 515.78 Synaptogyrin-2 OS=Homo sapiens OX=9606 GN=SYNGR2 PE=1 SV=1 4.21 2519.5 - 792769 - - - -0.4381 - 2.022 0.321 - 207.9 1 2 0 -0.0004 10 0 0 0 2.10E+07 2.46E+06 - - - 3.3771 0.9998 221125_WJC_METTL3_EV_vs_WT_F02.11245.11245.2 0.00141 16-Nov K.SPLQSVVVR[166.11].R "sp|Q9Y2W1|TR150_HUMAN,tr|A0A3B3ITZ9|A0A3B3ITZ9_HUMAN" 2 993.5847 2.46 12353 11245 2 993.584768 497.7996 Thyroid hormone receptor-associated protein 3 OS=Homo sapiens OX=9606 GN=THRAP3 PE=1 SV=2 9.47 2520.4 - 610809 - - - 0.1188 - 2.055 0.421 - 494 1 2 0 0.0001 9 0 0 0 6.55E+10 2.66E+10 - - - 4.2343 0.9924 221125_WJC_METTL3_EV_vs_WT_F02.11248.11248.2 0.293 16-Jul R.VFYTGQVVK.V "sp|Q14690|RRP5_HUMAN,tr|A0A3B3IUD7|A0A3B3IUD7_HUMAN" 2 1039.5702 0.69 12355 11248 2 1039.571249 520.7924 Protein RRP5 homolog OS=Homo sapiens OX=9606 GN=PDCD11 PE=1 SV=3 8.56 2520.8 - 1.25E+06 - - - 0.9783 - 1.341 0.15 - 117.9 1 2 0 0.001 9 0 0 0 3.30E+07 4.75E+07 - - - 0.9974 0.9991 221125_WJC_METTL3_EV_vs_WT_F02.11252.11252.2 0.0195 14-Sep K.LGDSWDVK.L "sp|Q96DA0|ZG16B_HUMAN,tr|A0A0C4DGN4|A0A0C4DGN4_HUMAN" 2 918.4447 2.01 12357 11252 2 918.445022 460.2296 Zymogen granule protein 16 homolog B OS=Homo sapiens OX=9606 GN=ZG16B PE=1 SV=3 4.21 2521.2 - 2.62E+06 - - - 0.3539 - 1.452 0.313 - 190.6 1 2 0 0.0003 8 0 0 0 1.08E+08 5.39E+07 - - - 2.4775 0.9977 221125_WJC_METTL3_EV_vs_WT_F02.11253.11253.3 0.0182 Sep-52 R.NALQQENHIIDGVK.V "sp|Q9GZT3|SLIRP_HUMAN,tr|H0YJW7|H0YJW7_HUMAN,tr|A0A087WUN7|A0A087WUN7_HUMAN,tr|G3V2S9|G3V2S9_HUMAN,tr|H0YJ40|H0YJ40_HUMAN,tr|G3V4X6|G3V4X6_HUMAN" 6 1577.8162 1.5 12358 11253 3 1577.81621 526.946 "SRA stem-loop-interacting RNA-binding protein, mitochondrial OS=Homo sapiens OX=9606 GN=SLIRP PE=1 SV=1" 5.32 2521.4 - 345927 - - - 0.026 - 1.597 0.266 - 94.7 1 2 0 0 14 0 0 0 8.86E+06 5.90E+06 - - - 2.7497 0.9986 221125_WJC_METTL3_EV_vs_WT_F02.11258.11258.2 0.2 12-May R.NTLMDMR[166.11].L sp|O94906|PRP6_HUMAN 1 889.4025 1.72 12361 11258 2 889.402244 445.7085 Pre-mRNA-processing factor 6 OS=Homo sapiens OX=9606 GN=PRPF6 PE=1 SV=1 5.84 2521.9 - 829819 - - - -0.3193 - 1.217 0.324 - 96.2 1 2 0 -0.0003 7 0 0 0 7.46E+07 4.34E+07 - - - 2.0562 0.9982 221125_WJC_METTL3_EV_vs_WT_F02.11259.11259.2 0.0525 14-Jun K.MMDIVAAK[136.11].E "sp|Q15643|TRIPB_HUMAN,tr|H0YJ97|H0YJ97_HUMAN" 2 885.4543 0.93 12362 11259 2 885.45481 443.7344 Thyroid receptor-interacting protein 11 OS=Homo sapiens OX=9606 GN=TRIP11 PE=1 SV=3 5.59 2522 - 1.33E+06 - - - 0.524 - 1.18 0.325 - 85.4 1 2 0 0.0005 8 0 0 0 1.49E+08 1.60E+08 - - - 1.9405 0.9998 221125_WJC_METTL3_EV_vs_WT_F02.11274.11274.2 0.0186 12-Sep R.MGLVMDR[166.11].M "sp|P52272|HNRPM_HUMAN,tr|A0A087X0X3|A0A087X0X3_HUMAN,tr|M0QZM1|M0QZM1_HUMAN" 3 830.4018 1.42 12370 11274 2 830.401619 416.2082 Heterogeneous nuclear ribonucleoprotein M OS=Homo sapiens OX=9606 GN=HNRNPM PE=1 SV=3 5.59 2523.8 - 3.41E+06 - - - -0.218 - 1.924 0.404 - 403 1 2 0 -0.0002 7 0 0 0 3.17E+08 2.23E+08 - - - 4.0984 0.9989 221125_WJC_METTL3_EV_vs_WT_F02.11275.11275.2 0.0717 12-Jul R.NTLMDMR.L sp|O94906|PRP6_HUMAN 1 879.3943 0.95 12371 11275 2 879.394134 440.7044 Pre-mRNA-processing factor 6 OS=Homo sapiens OX=9606 GN=PRPF6 PE=1 SV=1 5.84 2523.9 - 2.17E+06 - - - -0.141 - 1.326 0.316 - 178.8 1 2 0 -0.0001 7 0 0 0 7.56E+07 7.99E+07 - - - 2.269 0.9944 221125_WJC_METTL3_EV_vs_WT_F02.11281.11281.2 0.298 14-Jun K.VAIDVGYR.H "sp|P15121|ALDR_HUMAN,tr|E9PCX2|E9PCX2_HUMAN,tr|E9PEF9|E9PEF9_HUMAN" 3 891.4814 1.27 12375 11281 2 891.48271 446.748 Aldo-keto reductase family 1 member B1 OS=Homo sapiens OX=9606 GN=AKR1B1 PE=1 SV=3 5.81 2524.6 - 770451 - - - 1.4504 - 1.438 0.17 - 75.5 1 2 0 0.0013 8 0 0 0 9.12E+07 7.20E+07 - - - 1.3918 0.9992 221125_WJC_METTL3_EV_vs_WT_F02.11283.11283.2 0.264 14-Jul R.LYVGGLGK[136.11].E sp|Q8WVQ1|CANT1_HUMAN 1 813.484 1.14 12377 11283 2 813.483356 407.7493 Soluble calcium-activated nucleotidase 1 OS=Homo sapiens OX=9606 GN=CANT1 PE=1 SV=1 8.59 2524.7 - 1.09E+06 - - - -0.7794 - 1.606 0.297 - 133.9 1 2 0 -0.0006 8 0 0 0 4.72E+07 4.16E+07 - - - 2.6632 0.9997 221125_WJC_METTL3_EV_vs_WT_F02.11296.11296.2 0.000149 20-Aug R.LGMLSPEGTC[160.03]K[136.11].A "sp|P49327|FAS_HUMAN,tr|A0A0U1RQF0|A0A0U1RQF0_HUMAN" 2 1199.577 1.36 12385 11296 2 1199.579341 600.7958 Fatty acid synthase OS=Homo sapiens OX=9606 GN=FASN PE=1 SV=3 5.99 2526.1 - 246722 - - - 1.9682 - 1.958 0.537 - 207 1 2 0 0.0024 11 0 0 0 2.30E+07 1.69E+07 - - - 4.8243 0.9903 221125_WJC_METTL3_EV_vs_WT_F02.11299.11299.2 0.188 16-Jul R.LNSVLEVEK[136.11].S sp|Q9NU22|MDN1_HUMAN 1 1037.5848 0.64 12386 11299 2 1037.583789 519.7997 Midasin OS=Homo sapiens OX=9606 GN=MDN1 PE=1 SV=2 4.53 2526.5 - 321408 - - - -0.9994 - 1.324 0.123 - 101.2 1 2 0 -0.001 9 0 0 0 5.89E+07 9.21E+07 - - - 0.7611 0.9993 221125_WJC_METTL3_EV_vs_WT_F02.11303.11303.2 0.000888 18-Oct R.IITEGFEAAK[136.11].E sp|P40227|TCPZ_HUMAN 1 1085.5848 0.47 12389 11303 2 1085.586621 543.7997 T-complex protein 1 subunit zeta OS=Homo sapiens OX=9606 GN=CCT6A PE=1 SV=3 4.53 2527 - 361005 - - - 1.6535 - 2.007 0.322 - 206.1 1 2 0 0.0018 10 0 0 0 3.15E+09 6.66E+09 - - - 3.3633 0.9983 221125_WJC_METTL3_EV_vs_WT_F02.11306.11306.2 0.012 14-Jul K.FLQQALDR[166.11].T sp|Q9UQR1|ZN148_HUMAN 1 999.5377 0.98 12391 11306 2 999.536005 500.7761 Zinc finger protein 148 OS=Homo sapiens OX=9606 GN=ZNF148 PE=1 SV=2 5.84 2527.3 - 1.31E+06 - - - -1.6958 - 1.451 0.303 - 157.7 1 2 0 -0.0017 8 0 0 0 3.34E+07 3.40E+07 - - - 2.4011 0.9982 221125_WJC_METTL3_EV_vs_WT_F02.11326.11326.2 0.213 12-Jun K.IYVLLR[166.11]R[166.11].Q sp|P84090|ERH_HUMAN 1 951.6133 2.27 12402 11326 2 951.613672 476.8139 Enhancer of rudimentary homolog OS=Homo sapiens OX=9606 GN=ERH PE=1 SV=1 10.84 2529.6 - 2.45E+06 - - - 0.4319 - 1.318 0.273 - 81.2 1 2 0 0.0004 7 0 0 0 1.13E+09 4.99E+08 - - - 1.9321 0.9993 221125_WJC_METTL3_EV_vs_WT_F02.11329.11329.2 0.00796 20-Nov K.LSAMMGAVAEK[136.11].K "sp|Q86U44|MTA70_HUMAN,tr|F5H6D8|F5H6D8_HUMAN,tr|H0YFV6|H0YFV6_HUMAN,tr|B4DTN4|B4DTN4_HUMAN" 4 1114.5606 0.84 12405 11329 2 1114.559825 558.2876 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 6 2529.9 - 692448 - - - -0.6971 - 1.664 0.325 - 95.6 1 2 0 -0.0008 11 0 0 0 2.32E+07 2.78E+07 - - - 2.8188 0.9966 221125_WJC_METTL3_EV_vs_WT_F02.11337.11337.2 0.139 12-Jun K.VLPTIPK[136.11].E "sp|P35606|COPB2_HUMAN,sp|Q8ND07|BBOF1_HUMAN,tr|H0Y938|H0Y938_HUMAN,tr|A0A7I2V258|A0A7I2V258_HUMAN,tr|H0YAC7|H0YAC7_HUMAN" 5 774.5095 0.51 12411 11337 2 774.509217 388.262 Coatomer subunit beta' OS=Homo sapiens OX=9606 GN=COPB2 PE=1 SV=2 8.72 2530.8 - 535767 - - - -0.3344 - 1.141 0.262 - 104.4 1 2 0 -0.0003 7 0 0 0 7.89E+07 1.54E+08 - - - 1.394 0.9997 221125_WJC_METTL3_EV_vs_WT_F02.11345.11345.2 0.00316 18-Sep K.TLLADQGEIR.V sp|O94776|MTA2_HUMAN 1 1114.5982 0.6 12415 11345 2 1114.598642 558.3064 Metastasis-associated protein MTA2 OS=Homo sapiens OX=9606 GN=MTA2 PE=1 SV=1 4.37 2531.8 - 876357 - - - 0.3625 - 1.844 0.396 - 95.6 1 2 0 0.0004 10 0 0 0 6.17E+07 1.03E+08 - - - 3.6738 0.9567 221125_WJC_METTL3_EV_vs_WT_F02.11347.11347.2 0.224 14-Jul R.ALEIYATR.L "sp|Q9H0B6|KLC2_HUMAN,tr|A8MZ87|A8MZ87_HUMAN" 2 935.5076 0.98 12417 11347 2 935.502756 468.7611 Kinesin light chain 2 OS=Homo sapiens OX=9606 GN=KLC2 PE=1 SV=1 6.05 2532.1 - 1.17E+06 - - - -5.2121 - 1.607 0.178 - 133.7 1 2 0 -0.0049 8 0 0 0 4.87E+07 4.99E+07 - - - 1.7849 0.9995 221125_WJC_METTL3_EV_vs_WT_F02.11350.11350.2 0.013 18-Oct K.TLLADQGEIR[166.11].V sp|O94776|MTA2_HUMAN 1 1124.6065 0.6 12418 11350 2 1124.60386 563.3105 Metastasis-associated protein MTA2 OS=Homo sapiens OX=9606 GN=MTA2 PE=1 SV=1 4.37 2532.5 - 1.38E+06 - - - -2.3546 - 1.918 0.453 - 304.2 1 2 0 -0.0026 10 0 0 0 6.17E+07 1.03E+08 - - - 4.204 0.998 221125_WJC_METTL3_EV_vs_WT_F02.11357.11357.2 0.537 12-Jul R.FSDIQIR.R "sp|P11586|C1TC_HUMAN,tr|F5H2F4|F5H2F4_HUMAN,tr|V9GZ78|V9GZ78_HUMAN,tr|V9GYY3|V9GYY3_HUMAN,tr|A0A494C1T2|A0A494C1T2_HUMAN" 5 877.4658 1.38 12420 11357 2 877.4657 439.7402 "C-1-tetrahydrofolate synthase, cytoplasmic OS=Homo sapiens OX=9606 GN=MTHFD1 PE=1 SV=4" 5.84 2533.4 - 1.39E+07 - - - -0.0764 - 1.692 0.147 - 144.8 1 2 0 -0.0001 7 0 0 0 3.90E+08 2.83E+08 - - - 1.7931 0.9985 221125_WJC_METTL3_EV_vs_WT_F02.11359.11359.2 0.329 12-Aug K.IYVLLRR.Q sp|P84090|ERH_HUMAN 1 931.5967 2.27 12421 11359 2 931.595741 466.8056 Enhancer of rudimentary homolog OS=Homo sapiens OX=9606 GN=ERH PE=1 SV=1 10.84 2533.6 - 1.88E+07 - - - -1.052 - 1.481 0.257 - 215.6 1 2 0 -0.001 7 0 0 0 1.13E+09 4.99E+08 - - - 2.1832 0.8914 221125_WJC_METTL3_EV_vs_WT_F02.11360.11360.2 0.0062 12-Jul K.SLNNQFA.S sp|P04264|K2C1_HUMAN 1 792.3766 - 12422 11360 2 792.375756 397.1956 "Keratin, type II cytoskeletal 1 OS=Homo sapiens OX=9606 GN=KRT1 PE=1 SV=6" 5.24 2533.7 - 1.08E+07 - - - -1.0866 - 1.1 0.354 - 140.9 1 1 0 -0.0009 7 0 0 0 - - - - - 1.9574 0.9696 221125_WJC_METTL3_EV_vs_WT_F02.11361.11361.2 0.0133 14-Jul K.GVPVISVK.T sp|Q15424|SAFB1_HUMAN 1 797.5011 1.26 12423 11361 2 797.499785 399.7578 Scaffold attachment factor B1 OS=Homo sapiens OX=9606 GN=SAFB PE=1 SV=4 8.75 2533.7 - 3.96E+06 - - - -1.6364 - 1.157 0.1 - 176.2 1 2 0 -0.0013 8 0 0 0 2.67E+08 2.12E+08 - - - 0.219 0.9964 221125_WJC_METTL3_EV_vs_WT_F02.11362.11362.2 0.0751 16-Oct K.LTDAQILTR.L "sp|P35250|RFC2_HUMAN,tr|A0A087WVY3|A0A087WVY3_HUMAN,tr|H7C5P4|H7C5P4_HUMAN" 3 1029.5819 0.67 12424 11362 2 1029.579293 515.7982 Replication factor C subunit 2 OS=Homo sapiens OX=9606 GN=RFC2 PE=1 SV=3 5.84 2533.8 - 1.28E+06 - - - -2.4923 - 1.82 0.196 - 262.6 1 2 0 -0.0026 9 0 0 0 6.01E+07 8.96E+07 - - - 2.2203 0.8296 221125_WJC_METTL3_EV_vs_WT_F02.11365.11365.2 2.08 12-Aug E.LSELQLR[166.11].L "sp|O60293|ZC3H1_HUMAN,sp|Q15751|HERC1_HUMAN,sp|Q9BVK6|TMED9_HUMAN" 3 867.5053 1.4 12425 11365 2 867.504593 434.7599 Zinc finger C3H1 domain-containing protein OS=Homo sapiens OX=9606 GN=ZFC3H1 PE=1 SV=3 6 2534.2 - 5.62E+06 - - - -0.8576 - 1.7 0.102 - 200 1 1 0 -0.0007 7 0 0 0 2.97E+08 2.13E+08 - - - 1.4755 0.9841 221125_WJC_METTL3_EV_vs_WT_F02.11367.11367.2 0.356 14-Jul K.GVPVISVK[136.11].T sp|Q15424|SAFB1_HUMAN 1 805.5153 1.26 12427 11367 2 805.514122 403.7649 Scaffold attachment factor B1 OS=Homo sapiens OX=9606 GN=SAFB PE=1 SV=4 8.75 2534.3 - 4.16E+06 - - - -1.45 - 1.393 0.091 - 138.8 2 2 0 -0.0012 8 0 0 0 2.67E+08 2.12E+08 - - - 0.578 0.9893 221125_WJC_METTL3_EV_vs_WT_F02.11371.11371.2 0.235 14-Sep R.ALEIYATR[166.11].L "sp|Q9H0B6|KLC2_HUMAN,tr|A8MZ87|A8MZ87_HUMAN" 2 945.5159 0.98 12429 11371 2 945.515635 473.7652 Kinesin light chain 2 OS=Homo sapiens OX=9606 GN=KLC2 PE=1 SV=1 6.05 2534.8 - 666940 - - - -0.2824 - 1.504 0.041 - 251.3 1 2 0 -0.0003 8 0 0 0 4.87E+07 4.99E+07 - - - 0.5746 0.9995 221125_WJC_METTL3_EV_vs_WT_F02.11380.11380.2 6.84E-06 18-Oct R.IITEGFEAAK.E sp|P40227|TCPZ_HUMAN 1 1077.5706 0.47 12433 11380 2 1077.569706 539.7926 T-complex protein 1 subunit zeta OS=Homo sapiens OX=9606 GN=CCT6A PE=1 SV=3 4.53 2536.1 - 8.14E+07 - - - -0.8538 - 1.959 0.311 - 211.3 1 2 0 -0.0009 10 0 0 0 3.15E+09 6.66E+09 - - - 3.2147 0.808 221125_WJC_METTL3_EV_vs_WT_F02.11390.11390.2 0.118 20-Jul R.LGASEAGDWLR.R sp|Q8N7G0|PO5F2_HUMAN 1 1173.5778 999 12439 11390 2 1174.579266 587.7962 "POU domain, class 5, transcription factor 2 OS=Homo sapiens OX=9606 GN=POU5F2 PE=1 SV=1" 4.37 2537.3 - 503495 - - - 853.3137 - 1.274 0.271 - 128.4 1 2 0 1.0014 11 0 0 0 7.30E+06 0.00E+00 - - - 1.3833 0.9996 221125_WJC_METTL3_EV_vs_WT_F02.11393.11393.2 0.000167 18-Sep R.YVMTTTTLER.T "sp|P05198|IF2A_HUMAN,tr|H0YJS4|H0YJS4_HUMAN,tr|G3V4T5|G3V4T5_HUMAN" 3 1213.6013 0.87 12440 11393 2 1213.599703 607.8079 Eukaryotic translation initiation factor 2 subunit 1 OS=Homo sapiens OX=9606 GN=EIF2S1 PE=1 SV=3 6 2537.7 - 537801 - - - -1.2945 - 1.527 0.458 - 266.8 1 2 0 -0.0016 10 0 0 0 2.52E+08 2.90E+08 - - - 3.6049 0.998 221125_WJC_METTL3_EV_vs_WT_F02.11397.11397.2 0.000169 18-Nov K.VFLATNSDYK.Y "sp|P49902|5NTC_HUMAN,tr|A0A6Q8PHB5|A0A6Q8PHB5_HUMAN,tr|A0A6Q8PHP0|A0A6Q8PHP0_HUMAN,tr|Q5JUV4|Q5JUV4_HUMAN" 4 1156.5764 1.02 12442 11397 2 1156.571862 579.2955 Cytosolic purine 5'-nucleotidase OS=Homo sapiens OX=9606 GN=NT5C2 PE=1 SV=1 5.81 2538.1 - 701953 - - - -3.9582 - 1.8 0.445 - 312.9 1 2 0 -0.0046 10 0 0 0 1.20E+07 1.17E+07 - - - 3.967 0.9997 221125_WJC_METTL3_EV_vs_WT_F02.11400.11400.2 2.04E-05 18-Nov R.YVMTTTTLER[166.11].T "sp|P05198|IF2A_HUMAN,tr|H0YJS4|H0YJS4_HUMAN,tr|G3V4T5|G3V4T5_HUMAN" 3 1223.6095 0.87 12443 11400 2 1223.607897 612.812 Eukaryotic translation initiation factor 2 subunit 1 OS=Homo sapiens OX=9606 GN=EIF2S1 PE=1 SV=3 6 2538.5 - 1.92E+06 - - - -1.346 - 1.677 0.48 - 253.6 1 2 0 -0.0016 10 0 0 0 2.52E+08 2.90E+08 - - - 4.0289 0.999 221125_WJC_METTL3_EV_vs_WT_F02.11402.11402.2 0.0348 12-Jul K.AC[160.03]TILLR[166.11].G "sp|P49368|TCPG_HUMAN,tr|B4DUR8|B4DUR8_HUMAN" 2 855.4876 0.23 12444 11402 2 855.486184 428.7511 T-complex protein 1 subunit gamma OS=Homo sapiens OX=9606 GN=CCT3 PE=1 SV=4 8.29 2538.7 - 2.01E+07 - - - -1.6306 - 1.598 0.31 - 328.7 1 2 0 -0.0014 7 0 0 0 3.42E+08 1.46E+09 - - - 2.8155 0.998 221125_WJC_METTL3_EV_vs_WT_F02.11406.11406.2 0.00189 14-Aug K.EIEYEVVR.D "sp|P31327|CPSM_HUMAN,sp|P27708|PYR1_HUMAN,tr|F8VPD4|F8VPD4_HUMAN,tr|A0A669KBF2|A0A669KBF2_HUMAN" 4 1035.5237 1.51 12446 11406 2 1035.520624 518.7691 "Carbamoyl-phosphate synthase [ammonia], mitochondrial OS=Homo sapiens OX=9606 GN=CPS1 PE=1 SV=2" 4.25 2539.2 - 3.07E+06 - - - -2.9473 - 1.577 0.365 - 306.3 1 2 0 -0.0031 8 0 0 0 1.10E+08 7.27E+07 - - - 3.1098 0.999 221125_WJC_METTL3_EV_vs_WT_F02.11415.11415.2 0.0198 14-Jun R.FPNKPYLS.- sp|Q96BP2|CHCH1_HUMAN 1 964.5018 1.33 12451 11415 2 964.500416 483.2582 Coiled-coil-helix-coiled-coil-helix domain-containing protein 1 OS=Homo sapiens OX=9606 GN=CHCHD1 PE=1 SV=1 8.59 2540.3 - 2.63E+07 - - - -1.4536 - 1.367 0.373 - 90.6 1 2 0 -0.0014 8 0 0 0 3.40E+09 2.57E+09 - - - 2.7384 0.9995 221125_WJC_METTL3_EV_vs_WT_F02.11416.11416.2 0.00294 14-Jul R.FPNK[136.11]PYLS.- sp|Q96BP2|CHCH1_HUMAN 1 972.516 1.32 12452 11416 2 972.515274 487.2653 Coiled-coil-helix-coiled-coil-helix domain-containing protein 1 OS=Homo sapiens OX=9606 GN=CHCHD1 PE=1 SV=1 8.59 2540.3 - 2.23E+07 - - - -0.765 - 1.54 0.389 - 112.8 1 2 0 -0.0007 8 0 0 0 3.36E+09 2.54E+09 - - - 3.2162 0.9896 221125_WJC_METTL3_EV_vs_WT_F02.11422.11422.2 0.0175 12-May K.FYEAFSK[136.11].N sp|P08238|HS90B_HUMAN 1 898.4316 0.83 12454 11422 2 898.429126 450.2231 Heat shock protein HSP 90-beta OS=Homo sapiens OX=9606 GN=HSP90AB1 PE=1 SV=4 6 2541.1 - 9.01E+06 - - - -2.7759 - 1.1 0.298 - 84.7 1 2 0 -0.0025 7 0 0 0 8.16E+08 9.77E+08 - - - 1.5432 0.9996 221125_WJC_METTL3_EV_vs_WT_F02.11434.11434.2 0.0101 16-Oct K.SPLQSVVVR.R "sp|Q9Y2W1|TR150_HUMAN,tr|A0A3B3ITZ9|A0A3B3ITZ9_HUMAN" 2 983.5764 2.46 12458 11434 2 983.574319 492.7955 Thyroid hormone receptor-associated protein 3 OS=Homo sapiens OX=9606 GN=THRAP3 PE=1 SV=2 9.47 2542.6 - 1.07E+09 - - - -2.0954 - 2.207 0.378 - 577.6 1 2 0 -0.0021 9 0 0 0 6.55E+10 2.66E+10 - - - 4.1225 0.9494 221125_WJC_METTL3_EV_vs_WT_F02.11435.11435.2 0.0348 12-Aug R.WDPSLTR[166.11].E "sp|Q13724|MOGS_HUMAN,tr|A0A3B3IS52|A0A3B3IS52_HUMAN,tr|A0A3B3IRK6|A0A3B3IRK6_HUMAN,tr|A0A3B3IRW2|A0A3B3IRW2_HUMAN" 4 883.4427 0.88 12459 11435 2 883.438616 442.7286 Mannosyl-oligosaccharide glucosidase OS=Homo sapiens OX=9606 GN=MOGS PE=1 SV=5 5.84 2542.7 - 3.90E+06 - - - -4.6647 - 1.383 0.175 - 323.7 1 2 0 -0.0041 7 0 0 0 9.76E+07 1.10E+08 - - - 1.3597 0.9963 221125_WJC_METTL3_EV_vs_WT_F02.11440.11440.2 0.000479 16-Sep K.LTMLNTVSK[136.11].L "sp|Q99961|SH3G1_HUMAN,tr|M0R0I3|M0R0I3_HUMAN,tr|M0QYE0|M0QYE0_HUMAN" 3 1013.5671 1.81 12462 11440 2 1013.56268 507.7908 Endophilin-A2 OS=Homo sapiens OX=9606 GN=SH3GL1 PE=1 SV=1 8.75 2543.3 - 0 - - - -4.3283 - 1.744 0.391 - 219.4 1 2 0 -0.0044 9 0 0 0 3.63E+08 2.01E+08 - - - 3.5366 0.9814 221125_WJC_METTL3_EV_vs_WT_F02.11447.11447.2 3.08 14-Jun R.LVGIISSR.D "sp|P12268|IMDH2_HUMAN,tr|A0A7I2YQK5|A0A7I2YQK5_HUMAN,tr|H0Y4R1|H0Y4R1_HUMAN,tr|A0A7I2V2T3|A0A7I2V2T3_HUMAN,tr|E7ETK5|E7ETK5_HUMAN" 5 843.5178 0.72 12465 11447 2 843.519053 422.7662 Inosine-5'-monophosphate dehydrogenase 2 OS=Homo sapiens OX=9606 GN=IMPDH2 PE=1 SV=2 9.75 2544.1 - 5.84E+06 - - - 1.4831 - 1.13 0.155 - 123.6 1 2 0 0.0013 8 0 0 0 2.68E+08 3.71E+08 - - - 0.554 0.9484 221125_WJC_METTL3_EV_vs_WT_F02.11450.11450.2 0.209 14-Aug K.LADISLGK.E sp|Q02413|DSG1_HUMAN 1 815.4753 999 12466 11450 2 815.471566 408.7449 Desmoglein-1 OS=Homo sapiens OX=9606 GN=DSG1 PE=1 SV=2 5.84 2544.4 - 4.35E+06 - - - -4.5409 - 1.745 0.076 - 159.2 1 2 0 -0.0037 8 0 0 0 4.11E+08 0.00E+00 - - - 1.2803 0.9539 221125_WJC_METTL3_EV_vs_WT_F02.11452.11452.2 0.00358 16-Sep S.AMMGAVAEK[136.11].K "sp|Q86U44|MTA70_HUMAN,tr|F5H6D8|F5H6D8_HUMAN,tr|H0YFV6|H0YFV6_HUMAN,tr|B4DTN4|B4DTN4_HUMAN" 4 914.4445 0.17 12468 11452 2 914.442238 458.2295 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 6.05 2544.5 - 5.31E+06 - - - -2.4835 - 1.719 0.423 - 219.6 1 1 0 -0.0023 9 0 0 0 1.19E+08 6.88E+08 - - - 3.7319 0.9995 221125_WJC_METTL3_EV_vs_WT_F02.11459.11459.2 0.0103 14-Aug R.VATPVDWK[136.11].D sp|P30041|PRDX6_HUMAN 1 922.5004 0.76 12469 11459 2 922.498425 462.2575 Peroxiredoxin-6 OS=Homo sapiens OX=9606 GN=PRDX6 PE=1 SV=3 5.81 2545.6 - 0 - - - -2.1062 - 1.783 0.429 - 303.1 1 2 0 -0.0019 8 0 0 0 6.11E+07 8.08E+07 - - - 3.9531 0.9805 221125_WJC_METTL3_EV_vs_WT_F02.11463.11463.2 0.0705 14-Sep R.LVGIISSR[166.11].D "sp|P12268|IMDH2_HUMAN,tr|A0A7I2YQK5|A0A7I2YQK5_HUMAN,tr|H0Y4R1|H0Y4R1_HUMAN,tr|A0A7I2V2T3|A0A7I2V2T3_HUMAN,tr|E7ETK5|E7ETK5_HUMAN" 5 853.5261 0.72 12470 11463 2 853.522682 427.7703 Inosine-5'-monophosphate dehydrogenase 2 OS=Homo sapiens OX=9606 GN=IMPDH2 PE=1 SV=2 9.75 2546.2 - 9.16E+06 - - - -3.9718 - 1.708 0.145 - 291.4 1 2 0 -0.0034 8 0 0 0 2.68E+08 3.71E+08 - - - 1.7254 0.9727 221125_WJC_METTL3_EV_vs_WT_F02.11464.11464.2 0.543 14-Sep R.VITALVER[166.11].T "sp|P52732|KIF11_HUMAN,tr|A0A7I2YQY4|A0A7I2YQY4_HUMAN,tr|A0A7I2V3A9|A0A7I2V3A9_HUMAN,tr|A0A7I2V3V3|A0A7I2V3V3_HUMAN" 4 909.5523 4.52 12471 11464 2 909.548512 455.7834 Kinesin-like protein KIF11 OS=Homo sapiens OX=9606 GN=KIF11 PE=1 SV=2 5.97 2546.2 - 4.12E+06 - - - -4.1504 - 1.414 0.2 - 257 1 2 0 -0.0038 8 0 0 0 4.01E+09 8.88E+08 - - - 1.5618 0.9905 221125_WJC_METTL3_EV_vs_WT_F02.11468.11468.2 0.0694 14-Aug R.VITALVER.T "sp|P52732|KIF11_HUMAN,tr|A0A7I2YQY4|A0A7I2YQY4_HUMAN,tr|A0A7I2V3A9|A0A7I2V3A9_HUMAN,tr|A0A7I2V3V3|A0A7I2V3V3_HUMAN" 4 899.544 4.52 12472 11468 2 899.539696 450.7793 Kinesin-like protein KIF11 OS=Homo sapiens OX=9606 GN=KIF11 PE=1 SV=2 5.97 2546.8 - 2.74E+07 - - - -4.8035 - 1.393 0.385 - 178.8 1 2 0 -0.0043 8 0 0 0 4.02E+09 8.89E+08 - - - 2.8829 0.9936 221125_WJC_METTL3_EV_vs_WT_F02.11469.11469.2 0.463 12-Aug R.LNELLVK.A "sp|Q12931|TRAP1_HUMAN,tr|I3L0K7|I3L0K7_HUMAN,tr|I3L253|I3L253_HUMAN" 3 827.5117 1.12 12473 11469 2 827.508735 414.7631 "Heat shock protein 75 kDa, mitochondrial OS=Homo sapiens OX=9606 GN=TRAP1 PE=1 SV=3" 6 2546.9 - 4.02E+06 - - - -3.5274 - 1.953 0.167 - 187.9 1 2 0 -0.0029 7 0 0 0 4.61E+08 4.13E+08 - - - 2.3945 0.9593 221125_WJC_METTL3_EV_vs_WT_F02.11480.11480.2 7.89 12-Jun R.LSEADIR.G "sp|P19971|TYPH_HUMAN,sp|Q13017|RHG05_HUMAN,tr|A0A494C1L9|A0A494C1L9_HUMAN,tr|A0A494BZZ4|A0A494BZZ4_HUMAN,tr|C9JGI3|C9JGI3_HUMAN,tr|A0A0A0MSK6|A0A0A0MSK6_HUMAN" 6 802.4185 1.38 12478 11480 2 802.418587 402.2165 Thymidine phosphorylase OS=Homo sapiens OX=9606 GN=TYMP PE=1 SV=2 4.37 2548.2 - 6.31E+06 - - - 0.1309 - 1.13 0.037 - 117.8 1 2 0 0.0001 7 0 0 0 1.51E+09 1.09E+09 - - - -0.2985 0.9973 221125_WJC_METTL3_EV_vs_WT_F02.11483.11483.2 0.0465 14-Jun K.SVNELIYK[136.11].R "sp|P18124|RL7_HUMAN,tr|A8MUD9|A8MUD9_HUMAN" 2 972.5371 0.6 12479 11483 2 972.536954 487.2758 60S ribosomal protein L7 OS=Homo sapiens OX=9606 GN=RPL7 PE=1 SV=1 5.72 2548.6 - 8.24E+06 - - - -0.1985 - 1.251 0.247 - 90.6 1 2 0 -0.0002 8 0 0 0 2.79E+08 4.68E+08 - - - 1.5407 0.9571 221125_WJC_METTL3_EV_vs_WT_F02.11484.11484.2 2.5 12-Aug R.SLLTYGR[166.11].R sp|P31930|QCR1_HUMAN 1 818.4526 1.33 12480 11484 2 818.45144 410.2336 "Cytochrome b-c1 complex subunit 1, mitochondrial OS=Homo sapiens OX=9606 GN=UQCRC1 PE=1 SV=3" 8.46 2548.7 - 2.09E+06 - - - -1.3843 - 1.128 0.064 - 234.2 1 2 0 -0.0011 7 0 0 0 1.13E+08 8.51E+07 - - - -0.105 0.7929 221125_WJC_METTL3_EV_vs_WT_F02.11489.11489.2 0.14 14-Jul K.GIVEFASK.P sp|P23246|SFPQ_HUMAN 1 849.4596 0.8 12482 11489 2 849.456644 425.7371 "Splicing factor, proline- and glutamine-rich OS=Homo sapiens OX=9606 GN=SFPQ PE=1 SV=2" 6 2549.3 - 4.44E+06 - - - -3.5022 - 1.551 0.321 - 174.3 1 1 0 -0.003 8 0 0 0 3.20E+08 4.00E+08 - - - 2.7347 0.9998 221125_WJC_METTL3_EV_vs_WT_F02.11491.11491.2 0.0075 20-Oct K.LSAMMGAVAEK.K "sp|Q86U44|MTA70_HUMAN,tr|F5H6D8|F5H6D8_HUMAN,tr|H0YFV6|H0YFV6_HUMAN,tr|B4DTN4|B4DTN4_HUMAN" 4 1106.5464 0.03 12483 11491 2 1106.545946 554.2805 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 6 2549.5 - 1.29E+08 - - - -0.4121 - 2.121 0.442 - 238.2 1 2 0 -0.0005 11 0 0 0 1.63E+10 5.10E+11 - - - 4.3395 0.9998 221125_WJC_METTL3_EV_vs_WT_F02.11495.11495.2 0.000794 16-Oct R.VITIMQNPR[166.11].Q sp|P62269|RS18_HUMAN 1 1080.5989 0.84 12484 11495 2 1080.598147 541.3067 40S ribosomal protein S18 OS=Homo sapiens OX=9606 GN=RPS18 PE=1 SV=3 9.72 2550 - 3.11E+06 - - - -0.7153 - 2.156 0.43 - 442.1 1 2 0 -0.0008 9 0 0 0 1.40E+09 1.66E+09 - - - 4.4393 0.9992 221125_WJC_METTL3_EV_vs_WT_F02.11501.11501.2 0.000906 16-Oct K.SPLQSVVVR[166.11].R "sp|Q9Y2W1|TR150_HUMAN,tr|A0A3B3ITZ9|A0A3B3ITZ9_HUMAN" 2 993.5847 2.46 12486 11501 2 993.581242 497.7996 Thyroid hormone receptor-associated protein 3 OS=Homo sapiens OX=9606 GN=THRAP3 PE=1 SV=2 9.47 2550.9 - 4.49E+06 - - - -3.43 - 2.219 0.47 - 506.8 1 2 0 -0.0034 9 0 0 0 6.55E+10 2.66E+10 - - - 4.8173 0.9746 221125_WJC_METTL3_EV_vs_WT_F02.11504.11504.2 1.14 14-May K.SVNELIYK.R "sp|P18124|RL7_HUMAN,tr|A8MUD9|A8MUD9_HUMAN" 2 964.5229 0.6 12487 11504 2 964.522383 483.2687 60S ribosomal protein L7 OS=Homo sapiens OX=9606 GN=RPL7 PE=1 SV=1 5.72 2551.2 - 7.96E+06 - - - -0.5847 - 0.925 0.166 - 54.6 1 2 0 -0.0006 8 0 0 0 2.79E+08 4.63E+08 - - - 0.0318 0.9998 221125_WJC_METTL3_EV_vs_WT_F02.11505.11505.2 0.000176 16-Sep R.VITIMQNPR.Q sp|P62269|RS18_HUMAN 1 1070.5907 0.84 12488 11505 2 1070.590264 536.3026 40S ribosomal protein S18 OS=Homo sapiens OX=9606 GN=RPS18 PE=1 SV=3 9.72 2551.3 - 5.11E+06 - - - -0.3605 - 1.868 0.445 - 346.4 1 2 0 -0.0004 9 0 0 0 1.39E+09 1.65E+09 - - - 4.1354 0.8847 221125_WJC_METTL3_EV_vs_WT_F02.11510.11510.2 0.27 18-Dec L.LEALTLASAR[166.11].G "sp|Q14654|KCJ11_HUMAN,tr|A0A804HHV7|A0A804HHV7_HUMAN" 2 1053.6058 0.82 12490 11510 2 1053.605234 527.8102 ATP-sensitive inward rectifier potassium channel 11 OS=Homo sapiens OX=9606 GN=KCNJ11 PE=1 SV=2 6 2551.9 - 2.15E+06 - - - -0.5173 - 2.446 0.029 - 632.2 1 1 0 -0.0005 10 0 0 0 7.20E+07 8.78E+07 - - - 1.7517 0.9989 221125_WJC_METTL3_EV_vs_WT_F02.11511.11511.2 0.198 14-Oct R.LPLGTLSK[136.11].S "sp|O43148|MCES_HUMAN,tr|K7EP06|K7EP06_HUMAN,tr|K7ERH6|K7ERH6_HUMAN" 3 835.5259 1.24 12491 11511 2 835.525891 418.7702 mRNA cap guanine-N7 methyltransferase OS=Homo sapiens OX=9606 GN=RNMT PE=1 SV=1 8.75 2552 - 2.20E+06 - - - 0.0443 - 1.845 0.194 - 277.4 1 2 0 0 8 0 0 0 4.32E+08 3.49E+08 - - - 2.3211 0.9847 221125_WJC_METTL3_EV_vs_WT_F02.11522.11522.2 1.87E-06 18-Oct L.SAMMGAVAEK[136.11].K "sp|Q86U44|MTA70_HUMAN,tr|F5H6D8|F5H6D8_HUMAN,tr|H0YFV6|H0YFV6_HUMAN,tr|B4DTN4|B4DTN4_HUMAN" 4 1001.4765 0.001 12493 11522 2 1001.475315 501.7455 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 5.72 2553.7 - 5.81E+06 - - - -1.2212 - 1.87 0.451 - 345.5 1 1 0 -0.0012 10 0 0 0 0.00E+00 4.73E+08 - - - 4.1189 0.9272 221125_WJC_METTL3_EV_vs_WT_F02.11535.11535.2 0.52 16-Oct R.LAAAFAVSR[166.11].L "sp|P55084|ECHB_HUMAN,tr|F5GZQ3|F5GZQ3_HUMAN" 2 914.5213 0.69 12496 11535 2 914.517443 458.2679 "Trifunctional enzyme subunit beta, mitochondrial OS=Homo sapiens OX=9606 GN=HADHB PE=1 SV=3" 9.75 2555.6 - 4.35E+06 - - - -4.2405 - 1.317 0.139 - 236.1 1 2 0 -0.0039 9 0 0 0 8.59E+07 1.24E+08 - - - 0.8631 0.9841 221125_WJC_METTL3_EV_vs_WT_F02.11541.11541.2 0.0253 16-Aug K.EIAEAYLGK.T "sp|P11142|HSP7C_HUMAN,tr|E9PQQ4|E9PQQ4_HUMAN,tr|E9PKE3|E9PKE3_HUMAN,tr|E9PN89|E9PN89_HUMAN,tr|E9PLF4|E9PLF4_HUMAN,tr|E9PI65|E9PI65_HUMAN,tr|E9PK54|E9PK54_HUMAN,tr|E9PPY6|E9PPY6_HUMAN,tr|E9PQK7|E9PQK7_HUMAN" 9 992.5179 0.16 12498 11541 2 992.514164 497.2662 Heat shock cognate 71 kDa protein OS=Homo sapiens OX=9606 GN=HSPA8 PE=1 SV=1 4.53 2556.3 - 4.76E+06 - - - -3.7259 - 1.418 0.23 - 140 1 2 0 -0.0037 9 0 0 0 1.95E+09 1.19E+10 - - - 1.749 0.9662 221125_WJC_METTL3_EV_vs_WT_F02.11547.11547.2 0.329 12-Aug F.VNDIFER.L "sp|Q8N257|H2B3B_HUMAN,sp|P33778|H2B1B_HUMAN,sp|Q5QNW6|H2B2F_HUMAN,sp|P58876|H2B1D_HUMAN,sp|Q99880|H2B1L_HUMAN,sp|P62807|H2B1C_HUMAN,sp|Q99877|H2B1N_HUMAN,sp|P57053|H2BFS_HUMAN,sp|P23527|H2B1O_HUMAN,sp|O60814|H2B1K_HUMAN,sp|Q93079|H2B1H_HUMAN,sp|Q99879|H2B1M_HUMAN,sp|Q16778|H2B2E_HUMAN,sp|P06899|H2B1J_HUMAN,tr|U3KQK0|U3KQK0_HUMAN" 15 891.445 0.98 12501 11547 2 891.444333 446.7298 Histone H2B type 3-B OS=Homo sapiens OX=9606 GN=H2BU1 PE=1 SV=3 4.37 2557 - 1.99E+06 - - - -0.783 - 1.761 0.289 - 265.3 1 1 0 -0.0007 7 0 0 0 2.48E+08 2.51E+08 - - - 2.9684 0.9987 221125_WJC_METTL3_EV_vs_WT_F02.11552.11552.2 0.00393 16-Aug K.EIAEAYLGK[136.11].T "sp|P11142|HSP7C_HUMAN,tr|E9PQQ4|E9PQQ4_HUMAN,tr|E9PKE3|E9PKE3_HUMAN,tr|E9PN89|E9PN89_HUMAN,tr|E9PLF4|E9PLF4_HUMAN,tr|E9PI65|E9PI65_HUMAN,tr|E9PK54|E9PK54_HUMAN,tr|E9PPY6|E9PPY6_HUMAN,tr|E9PQK7|E9PQK7_HUMAN" 9 1000.5321 0.16 12504 11552 2 1000.530627 501.2733 Heat shock cognate 71 kDa protein OS=Homo sapiens OX=9606 GN=HSPA8 PE=1 SV=1 4.53 2557.6 - 7.59E+07 - - - -1.4342 - 1.604 0.279 - 294.4 1 2 0 -0.0014 9 0 0 0 1.95E+09 1.19E+10 - - - 2.4682 0.9365 221125_WJC_METTL3_EV_vs_WT_F02.11553.11553.2 0.0949 14-Jun K.MFVGQVPR.T "sp|Q92879|CELF1_HUMAN,tr|F5H4Y5|F5H4Y5_HUMAN,tr|G5EA30|G5EA30_HUMAN,tr|E9PSH0|E9PSH0_HUMAN,tr|E9PQK4|E9PQK4_HUMAN,tr|E9PKA1|E9PKA1_HUMAN,tr|E9PKU1|E9PKU1_HUMAN,tr|F5H0D8|F5H0D8_HUMAN" 8 932.4902 1.38 12505 11553 2 932.492447 467.2524 CUGBP Elav-like family member 1 OS=Homo sapiens OX=9606 GN=CELF1 PE=1 SV=2 9.5 2557.6 - 3.95E+06 - - - 2.4022 - 1.098 0.105 - 92.7 1 2 0 0.0022 8 0 0 0 2.09E+08 1.52E+08 - - - 0.0978 0.9657 221125_WJC_METTL3_EV_vs_WT_F02.11554.11554.2 0.449 16-Sep R.LAAAFAVSR.L "sp|P55084|ECHB_HUMAN,tr|F5GZQ3|F5GZQ3_HUMAN" 2 904.5131 0.68 12506 11554 2 904.50909 453.2638 "Trifunctional enzyme subunit beta, mitochondrial OS=Homo sapiens OX=9606 GN=HADHB PE=1 SV=3" 9.75 2557.7 - 3.13E+06 - - - -4.3792 - 1.778 0.109 - 240.9 1 2 0 -0.004 9 0 0 0 8.62E+07 1.27E+08 - - - 1.5098 0.9961 221125_WJC_METTL3_EV_vs_WT_F02.11561.11561.2 0.0782 14-Jul R.DLAALEDK[136.11].V "sp|Q13813|SPTN1_HUMAN,tr|A0A0D9SF54|A0A0D9SF54_HUMAN,tr|A0A0D9SGF6|A0A0D9SGF6_HUMAN" 3 881.4586 1.11 12509 11561 2 881.456292 441.7366 "Spectrin alpha chain, non-erythrocytic 1 OS=Homo sapiens OX=9606 GN=SPTAN1 PE=1 SV=3" 4.03 2558.6 - 1.07E+06 - - - -2.5764 - 1.365 0.303 - 154 1 2 0 -0.0023 8 0 0 0 3.01E+07 2.71E+07 - - - 2.2167 0.9988 221125_WJC_METTL3_EV_vs_WT_F02.11565.11565.2 0.0048 14-Aug R.LGLDYEER.V "sp|Q99623|PHB2_HUMAN,tr|F5H3X6|F5H3X6_HUMAN,tr|A0A7I2V5F0|A0A7I2V5F0_HUMAN,tr|F5GWA7|F5GWA7_HUMAN,tr|J3KPX7|J3KPX7_HUMAN,tr|F5GY37|F5GY37_HUMAN" 6 993.4767 0.99 12511 11565 2 993.476372 497.7456 Prohibitin-2 OS=Homo sapiens OX=9606 GN=PHB2 PE=1 SV=2 4.14 2559.1 - 2.40E+07 - - - -0.3553 - 1.444 0.276 - 164 1 2 0 -0.0004 8 0 0 0 5.56E+08 5.62E+08 - - - 2.1875 0.9949 221125_WJC_METTL3_EV_vs_WT_F02.11566.11566.2 0.129 14-Jul R.LLVVTDPR[166.11].A "sp|P08865|RSSA_HUMAN,tr|C9J9K3|C9J9K3_HUMAN,tr|A0A0C4DG17|A0A0C4DG17_HUMAN" 3 921.5523 0.75 12512 11566 2 921.550378 461.7834 40S ribosomal protein SA OS=Homo sapiens OX=9606 GN=RPSA PE=1 SV=4 5.84 2559.2 - 2.73E+06 - - - -2.0715 - 1.7 0.144 - 162.6 1 2 0 -0.0019 8 0 0 0 4.95E+08 6.63E+08 - - - 1.7043 0.8177 221125_WJC_METTL3_EV_vs_WT_F02.11567.11567.2 0.132 18-Sep T.AAAIAYGLDR[166.11].R "sp|P48741|HSP77_HUMAN,sp|P0DMV8|HS71A_HUMAN,sp|P0DMV9|HS71B_HUMAN,sp|P17066|HSP76_HUMAN,tr|A0A0G2JIW1|A0A0G2JIW1_HUMAN" 5 1029.5483 0.11 12513 11567 2 1029.545333 515.7814 Putative heat shock 70 kDa protein 7 OS=Homo sapiens OX=9606 GN=HSPA7 PE=5 SV=2 5.88 2559.3 - 2.18E+06 - - - -2.8469 - 1.867 0.224 - 256.9 1 1 0 -0.0029 10 0 0 0 1.96E+07 1.73E+08 - - - 2.4372 0.998 221125_WJC_METTL3_EV_vs_WT_F02.11569.11569.2 0.00265 14-Oct R.DLAALEDK.V "sp|Q13813|SPTN1_HUMAN,tr|A0A0D9SF54|A0A0D9SF54_HUMAN,tr|A0A0D9SGF6|A0A0D9SGF6_HUMAN" 3 873.4444 1.1 12515 11569 2 873.44157 437.7295 "Spectrin alpha chain, non-erythrocytic 1 OS=Homo sapiens OX=9606 GN=SPTAN1 PE=1 SV=3" 4.03 2559.6 - 1.27E+06 - - - -3.1977 - 1.854 0.325 - 320.4 1 2 0 -0.0028 8 0 0 0 3.03E+07 2.75E+07 - - - 3.3025 0.898 221125_WJC_METTL3_EV_vs_WT_F02.11572.11572.2 0.604 12-Aug F.VNDIFER[166.11].L "sp|Q8N257|H2B3B_HUMAN,sp|P33778|H2B1B_HUMAN,sp|Q5QNW6|H2B2F_HUMAN,sp|P58876|H2B1D_HUMAN,sp|Q99880|H2B1L_HUMAN,sp|P62807|H2B1C_HUMAN,sp|Q99877|H2B1N_HUMAN,sp|P57053|H2BFS_HUMAN,sp|P23527|H2B1O_HUMAN,sp|O60814|H2B1K_HUMAN,sp|Q93079|H2B1H_HUMAN,sp|Q99879|H2B1M_HUMAN,sp|Q16778|H2B2E_HUMAN,sp|P06899|H2B1J_HUMAN,tr|U3KQK0|U3KQK0_HUMAN" 15 901.4533 0.99 12516 11572 2 901.450528 451.7339 Histone H2B type 3-B OS=Homo sapiens OX=9606 GN=H2BU1 PE=1 SV=3 4.37 2559.9 - 5.78E+06 - - - -3.0761 - 1.876 0.301 - 247.6 1 1 0 -0.0028 7 0 0 0 2.49E+08 2.53E+08 - - - 3.2568 0.9999 221125_WJC_METTL3_EV_vs_WT_F02.11574.11574.2 1.35E-06 20-Nov K.LSAMMGAVAEK[136.11].K "sp|Q86U44|MTA70_HUMAN,tr|F5H6D8|F5H6D8_HUMAN,tr|H0YFV6|H0YFV6_HUMAN,tr|B4DTN4|B4DTN4_HUMAN" 4 1114.5606 0.03 12517 11574 2 1114.561066 558.2876 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 6 2560.1 - 2.47E+09 - - - 0.4163 - 2.29 0.587 - 382.5 1 2 0 0.0005 11 0 0 0 1.63E+10 5.09E+11 - - - 5.6179 0.9996 221125_WJC_METTL3_EV_vs_WT_F02.11575.11575.2 0.000328 18-Oct R.FTVLTESAAK.N sp|P07196|NFL_HUMAN 1 1065.5706 1.94 12518 11575 2 1065.568521 533.7926 Neurofilament light polypeptide OS=Homo sapiens OX=9606 GN=NEFL PE=1 SV=3 6 2560.3 - 2.87E+06 - - - -1.9755 - 1.799 0.452 - 317.5 1 2 0 -0.0021 10 0 0 0 1.04E+08 5.37E+07 - - - 4.018 0.9961 221125_WJC_METTL3_EV_vs_WT_F02.11576.11576.2 0.569 12-Aug K.STELLIR.K "sp|Q5TEC6|H3PS2_HUMAN,sp|Q16695|H31T_HUMAN,sp|P84243|H33_HUMAN,sp|Q6NXT2|H3C_HUMAN,sp|Q71DI3|H32_HUMAN,sp|P68431|H31_HUMAN,tr|B4DEB1|B4DEB1_HUMAN,tr|K7EK07|K7EK07_HUMAN,tr|K7ES00|K7ES00_HUMAN,tr|K7EP01|K7EP01_HUMAN,tr|K7EMV3|K7EMV3_HUMAN,tr|A0A590UJJ6|A0A590UJJ6_HUMAN" 12 830.4862 0.94 12519 11576 2 830.486463 416.2504 Histone HIST2H3PS2 OS=Homo sapiens OX=9606 GN=H3-2 PE=1 SV=1 5.72 2560.3 - 3.92E+06 - - - 0.3552 - 1.523 0.129 - 263.8 1 2 0 0.0003 7 0 0 0 6.29E+09 6.69E+09 - - - 1.3267 0.9899 221125_WJC_METTL3_EV_vs_WT_F02.11589.11589.2 0.922 14-Jul R.LLVVTDPR.A "sp|P08865|RSSA_HUMAN,tr|C9J9K3|C9J9K3_HUMAN,tr|A0A0C4DG17|A0A0C4DG17_HUMAN" 3 911.544 0.65 12526 11589 2 911.542169 456.7793 40S ribosomal protein SA OS=Homo sapiens OX=9606 GN=RPSA PE=1 SV=4 5.84 2561.8 - 6.07E+06 - - - -2.0273 - 1.222 0.205 - 168.7 1 2 0 -0.0018 8 0 0 0 4.24E+08 6.56E+08 - - - 1.1592 0.8893 221125_WJC_METTL3_EV_vs_WT_F02.11594.11594.2 0.514 12-Jul R.LAVYIDR.V "sp|P02545|LMNA_HUMAN,tr|A0A6Q8PF80|A0A6Q8PF80_HUMAN,tr|A0A804HL68|A0A804HL68_HUMAN,tr|A0A6Q8PFM1|A0A6Q8PFM1_HUMAN,tr|A0A6Q8PF59|A0A6Q8PF59_HUMAN,tr|A0A6Q8PFJ0|A0A6Q8PFJ0_HUMAN,tr|A0A6Q8PHQ9|A0A6Q8PHQ9_HUMAN,tr|A0A6Q8PGH0|A0A6Q8PGH0_HUMAN,tr|Q3BDU5|Q3BDU5_HUMAN" 9 848.4756 1.06 12529 11594 2 848.471272 425.2451 Prelamin-A\C OS=Homo sapiens OX=9606 GN=LMNA PE=1 SV=1 5.84 2562.3 - 2.38E+06 - - - -5.1044 - 1.342 0.136 - 179.3 1 2 0 -0.0043 7 0 0 0 1.79E+08 1.69E+08 - - - 0.9762 1 221125_WJC_METTL3_EV_vs_WT_F02.11597.11597.3 1.36E-06 16/56 R.STSHK[136.11]PDEIYGMIER[166.11].L sp|Q86U44|MTA70_HUMAN 1 1779.8581 0.001 12532 11597 3 1779.860923 594.2933 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 5.42 2562.7 - 1.08E+06 - - - 1.6119 - 2.783 0.561 - 294.6 1 2 0 0.0029 15 0 0 0 0.00E+00 1.02E+08 - - - 7.4646 0.9992 221125_WJC_METTL3_EV_vs_WT_F02.11600.11600.2 0.408 13/22 R.AVLLAGPPGTGK[136.11].T "sp|Q9Y265|RUVB1_HUMAN,tr|E7ETR0|E7ETR0_HUMAN" 2 1087.6481 0.64 12533 11600 2 1087.645698 544.8313 RuvB-like 1 OS=Homo sapiens OX=9606 GN=RUVBL1 PE=1 SV=1 8.8 2563.1 - 848459 - - - -2.2038 - 2.369 0.287 - 432 1 2 0 -0.0024 12 0 0 0 2.83E+07 4.45E+07 - - - 3.4293 0.9999 221125_WJC_METTL3_EV_vs_WT_F02.11605.11605.2 7.62E-07 13/22 R.FLEQQNQVLQTK.W "sp|Q7Z794|K2C1B_HUMAN,sp|P04264|K2C1_HUMAN,sp|P35908|K22E_HUMAN" 3 1474.778 999 12536 11605 2 1474.779223 738.3963 "Keratin, type II cytoskeletal 1b OS=Homo sapiens OX=9606 GN=KRT77 PE=1 SV=3" 6 2563.7 - 1.65E+06 - - - 0.834 - 2.457 0.553 - 492.9 1 2 0 0.0012 12 0 0 0 1.53E+08 0.00E+00 - - - 5.4903 0.9705 221125_WJC_METTL3_EV_vs_WT_F02.11607.11607.2 3.07 16-Jun K.VLLGVGDPK.L "sp|O00567|NOP56_HUMAN,tr|A0A494C128|A0A494C128_HUMAN,tr|Q5JXT2|Q5JXT2_HUMAN" 3 896.5331 0.89 12538 11607 2 896.533259 449.2738 Nucleolar protein 56 OS=Homo sapiens OX=9606 GN=NOP56 PE=1 SV=4 5.81 2564 - 765398 - - - 0.1573 - 1.158 0.079 - 98.8 2 2 0 0.0001 9 0 0 0 1.19E+08 1.34E+08 - - - -0.0856 0.9657 221125_WJC_METTL3_EV_vs_WT_F02.11610.11610.2 2.79 12-Jun K.IQLLEAK.F "sp|Q86U86|PB1_HUMAN,tr|E7EVG2|E7EVG2_HUMAN" 2 813.496 1.28 12539 11610 2 813.495712 407.7553 Protein polybromo-1 OS=Homo sapiens OX=9606 GN=PBRM1 PE=1 SV=1 6 2564.3 - 3.26E+06 - - - -0.3589 - 1.109 0.06 - 109.3 1 2 0 -0.0003 7 0 0 0 1.15E+08 8.98E+07 - - - -0.1881 0.9927 221125_WJC_METTL3_EV_vs_WT_F02.11613.11613.2 1.21 12-Jul K.ITEIELR[166.11].K sp|Q9P2I0|CPSF2_HUMAN 1 882.505 0.86 12542 11613 2 882.505894 442.2598 Cleavage and polyadenylation specificity factor subunit 2 OS=Homo sapiens OX=9606 GN=CPSF2 PE=1 SV=2 4.53 2564.5 - 1.46E+06 - - - 1.0096 - 1.718 0.038 - 167.9 1 2 0 0.0009 7 0 0 0 4.33E+07 5.04E+07 - - - 1.0361 0.9937 221125_WJC_METTL3_EV_vs_WT_F02.11620.11620.2 1.92 12-Jun K.VVDPFSK.K "sp|P61247|RS3A_HUMAN,tr|H0Y8L7|H0Y8L7_HUMAN,tr|D6RI02|D6RI02_HUMAN,tr|H0Y9Y4|H0Y9Y4_HUMAN,tr|E9PFI5|E9PFI5_HUMAN" 5 790.4225 0.94 12546 11620 2 790.423561 396.2185 40S ribosomal protein S3a OS=Homo sapiens OX=9606 GN=RPS3A PE=1 SV=2 5.81 2565.2 - 2.55E+06 - - - 1.336 - 1.165 0.235 - 133.2 1 2 0 0.0011 7 0 0 0 7.57E+08 8.09E+08 - - - 1.2603 0.9977 221125_WJC_METTL3_EV_vs_WT_F02.11628.11628.2 0.955 16-Nov R.LAAEQELIR[166.11].L sp|Q15149|PLEC_HUMAN 1 1051.5901 2.27 12549 11628 2 1051.591254 526.8023 Plectin OS=Homo sapiens OX=9606 GN=PLEC PE=1 SV=3 4.53 2566.2 - 1.29E+06 - - - 1.0698 - 1.74 0.172 - 400.8 1 2 0 0.0011 9 0 0 0 6.19E+07 2.73E+07 - - - 1.9135 0.9958 221125_WJC_METTL3_EV_vs_WT_F02.11630.11630.2 0.0142 16-Jul K.VLLGVGDPK[136.11].L "sp|O00567|NOP56_HUMAN,tr|A0A494C128|A0A494C128_HUMAN,tr|Q5JXT2|Q5JXT2_HUMAN" 3 904.5473 0.89 12550 11630 2 904.546618 453.2809 Nucleolar protein 56 OS=Homo sapiens OX=9606 GN=NOP56 PE=1 SV=4 5.81 2566.4 - 4.04E+06 - - - -0.7739 - 1.404 0.173 - 146 1 2 0 -0.0007 9 0 0 0 1.20E+08 1.34E+08 - - - 1.3002 0.9344 221125_WJC_METTL3_EV_vs_WT_F02.11632.11632.2 0.53 12-Jun K.GVPFEVK.G sp|Q12904|AIMP1_HUMAN 1 774.4276 0.89 12552 11632 2 774.425445 388.2211 Aminoacyl tRNA synthase complex-interacting multifunctional protein 1 OS=Homo sapiens OX=9606 GN=AIMP1 PE=1 SV=2 6 2566.6 - 3.59E+06 - - - -2.7698 - 1.02 0.151 - 135.9 1 2 0 -0.0021 7 0 0 0 1.32E+08 1.48E+08 - - - 0.2184 0.999 221125_WJC_METTL3_EV_vs_WT_F02.11634.11634.2 0.0551 16-Aug R.LVADYTLEK[136.11].K "sp|Q9Y4B4|ARIP4_HUMAN,tr|H0Y760|H0Y760_HUMAN" 2 1058.5739 2.2 12554 11634 2 1058.57487 530.2942 Helicase ARIP4 OS=Homo sapiens OX=9606 GN=RAD54L2 PE=1 SV=4 4.37 2566.8 - 496088 - - - 0.8908 - 1.506 0.317 - 145.3 1 2 0 0.0009 9 0 0 0 1.07E+07 4.86E+06 - - - 2.5666 0.8268 221125_WJC_METTL3_EV_vs_WT_F02.11640.11640.2 0.243 16-Aug R.IVNVSSLAH.H "sp|Q8TC12|RDH11_HUMAN,tr|G3V234|G3V234_HUMAN,tr|H0YIZ8|H0YIZ8_HUMAN,tr|G3V2G6|G3V2G6_HUMAN,tr|H0YJ46|H0YJ46_HUMAN" 5 938.5185 - 12557 11640 2 938.519489 470.2665 Retinol dehydrogenase 11 OS=Homo sapiens OX=9606 GN=RDH11 PE=1 SV=2 6.74 2567.5 - 1.07E+06 - - - 1.0208 - 1.469 0.194 - 117.5 1 1 0 0.001 9 0 0 0 - - - - - 1.5862 0.9915 221125_WJC_METTL3_EV_vs_WT_F02.11642.11642.4 0.121 Nov-84 R.STSHK[136.11]PDEIYGMIER[166.11].L sp|Q86U44|MTA70_HUMAN 1 1779.8581 0.001 12559 11642 4 1779.856551 445.9718 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 5.42 2567.6 - 2.55E+06 - - - -0.8444 - 1.878 0.204 - 93.8 1 2 0 -0.0015 15 0 0 0 0.00E+00 5.89E+07 - - - 1.2267 0.9976 221125_WJC_METTL3_EV_vs_WT_F02.11647.11647.2 0.0581 16-Aug K.EVMFPPGTR.G "sp|Q96DH6|MSI2H_HUMAN,tr|B4DHE8|B4DHE8_HUMAN,tr|A0A6Q8PGD8|A0A6Q8PGD8_HUMAN,tr|A0A6Q8PF05|A0A6Q8PF05_HUMAN,tr|B4DM51|B4DM51_HUMAN" 5 1032.5063 0.66 12562 11647 2 1032.504553 517.2604 RNA-binding protein Musashi homolog 2 OS=Homo sapiens OX=9606 GN=MSI2 PE=1 SV=1 6.1 2568.2 - 1.20E+06 - - - -1.6445 - 1.434 0.268 - 216.1 1 2 0 -0.0017 9 0 0 0 3.30E+07 4.99E+07 - - - 2.0628 0.9997 221125_WJC_METTL3_EV_vs_WT_F02.11648.11648.2 0.0011 18-Aug R.FLTQPQVVAR.A "sp|O43760|SNG2_HUMAN,sp|A8MWL6|SNG2L_HUMAN,tr|K7ENG9|K7ENG9_HUMAN,tr|K7ELS8|K7ELS8_HUMAN,tr|K7ELD9|K7ELD9_HUMAN" 5 1157.6557 1.66 12563 11648 2 1157.655406 579.8351 Synaptogyrin-2 OS=Homo sapiens OX=9606 GN=SYNGR2 PE=1 SV=1 9.75 2568.3 - 495409 - - - -0.2479 - 1.652 0.403 - 231.9 1 2 0 -0.0003 10 0 0 0 8.61E+06 5.20E+06 - - - 3.4187 0.9929 221125_WJC_METTL3_EV_vs_WT_F02.11653.11653.2 0.613 14-Jul K.AGIFQSVK[136.11].- sp|P09669|COX6C_HUMAN 1 856.4898 0.31 12565 11653 2 856.488551 429.2522 Cytochrome c oxidase subunit 6C OS=Homo sapiens OX=9606 GN=COX6C PE=1 SV=2 8.8 2568.9 - 4.85E+06 - - - -1.4618 - 1.318 0.172 - 115.2 1 2 0 -0.0013 8 0 0 0 2.06E+08 6.61E+08 - - - 1.1438 0.8037 221125_WJC_METTL3_EV_vs_WT_F02.11655.11655.2 0.051 14-Sep T.LLDIDNTR.M sp|P35527|K1C9_HUMAN 1 958.5084 0.89 12567 11655 2 958.505447 480.2615 "Keratin, type I cytoskeletal 9 OS=Homo sapiens OX=9606 GN=KRT9 PE=1 SV=3" 4.21 2569.1 - 1.19E+06 - - - -3.0391 - 1.697 0.25 - 207 1 1 0 -0.0029 8 0 0 0 2.71E+07 3.04E+07 - - - 2.4816 0.996 221125_WJC_METTL3_EV_vs_WT_F02.11656.11656.2 0.753 12-Jun K.EELAYLK.K "sp|Q04695|K1C17_HUMAN,sp|P13645|K1C10_HUMAN,sp|P02533|K1C14_HUMAN,sp|Q7Z3Y8|K1C27_HUMAN,sp|P08727|K1C19_HUMAN,sp|P19012|K1C15_HUMAN,tr|K7EPJ9|K7EPJ9_HUMAN,tr|K7ESE1|K7ESE1_HUMAN,tr|C9JM50|C9JM50_HUMAN,tr|A0A1B0GVI3|A0A1B0GVI3_HUMAN,tr|C9JTG5|C9JTG5_HUMAN,tr|F5GWP8|F5GWP8_HUMAN,tr|K7EMS3|K7EMS3_HUMAN,tr|A8MT21|A8MT21_HUMAN" 14 864.4593 236.48 12568 11656 2 864.458259 433.2369 "Keratin, type I cytoskeletal 17 OS=Homo sapiens OX=9606 GN=KRT17 PE=1 SV=2" 4.53 2569.1 - 1.10E+06 - - - -1.1857 - 1.437 0.172 - 110.1 1 2 0 -0.001 7 0 0 0 7.34E+08 3.10E+06 - - - 1.4599 0.9949 221125_WJC_METTL3_EV_vs_WT_F02.11657.11657.2 0.0165 18-Jul R.IYQGTLGAIK.V sp|Q9NRL2|BAZ1A_HUMAN 1 1062.6073 0.76 12569 11657 2 1062.603967 532.3109 Bromodomain adjacent to zinc finger domain protein 1A OS=Homo sapiens OX=9606 GN=BAZ1A PE=1 SV=2 8.59 2569.3 - 827672 - - - -3.1799 - 1.435 0.313 - 97.5 1 2 0 -0.0034 10 0 0 0 2.16E+07 2.83E+07 - - - 2.3599 0.9499 221125_WJC_METTL3_EV_vs_WT_F02.11658.11658.2 0.197 20-Jul K.TPGSLGDPVLK[136.11].R sp|Q96AV8|E2F7_HUMAN 1 1090.6114 10.06 12570 11658 2 1090.60725 546.313 Transcription factor E2F7 OS=Homo sapiens OX=9606 GN=E2F7 PE=1 SV=3 5.5 2569.4 - 1.44E+06 - - - -3.7823 - 1.265 0.185 - 92.3 2 2 0 -0.0041 11 0 0 0 6.35E+07 6.31E+06 - - - 0.9076 0.9991 221125_WJC_METTL3_EV_vs_WT_F02.11663.11663.2 0.00178 16-Oct R.LAAEQELIR.L sp|Q15149|PLEC_HUMAN 1 1041.5819 2.36 12572 11663 2 1041.579634 521.7982 Plectin OS=Homo sapiens OX=9606 GN=PLEC PE=1 SV=3 4.53 2570 - 1.73E+06 - - - -2.1362 - 1.989 0.309 - 333.9 1 2 0 -0.0022 9 0 0 0 6.44E+07 2.73E+07 - - - 3.3119 0.9996 221125_WJC_METTL3_EV_vs_WT_F02.11667.11667.2 0.0132 14-Aug R.FPNKPYLS.- sp|Q96BP2|CHCH1_HUMAN 1 964.5018 1.42 12575 11667 2 964.501084 483.2582 Coiled-coil-helix-coiled-coil-helix domain-containing protein 1 OS=Homo sapiens OX=9606 GN=CHCHD1 PE=1 SV=1 8.59 2570.5 - 9.45E+06 - - - -0.761 - 1.478 0.414 - 138.7 1 2 0 -0.0007 8 0 0 0 1.62E+09 1.15E+09 - - - 3.2769 0.9951 221125_WJC_METTL3_EV_vs_WT_F02.11670.11670.2 1.14 14-Jul R.GPLGPNWK[136.11].K "sp|P48739|PIPNB_HUMAN,sp|Q00169|PIPNA_HUMAN,tr|I3L459|I3L459_HUMAN,tr|A0A0A0MSW4|A0A0A0MSW4_HUMAN,tr|F5GWE5|F5GWE5_HUMAN,tr|B3KYB6|B3KYB6_HUMAN,tr|I3L4H1|I3L4H1_HUMAN,tr|I3L4C0|I3L4C0_HUMAN" 8 875.4745 1.75 12577 11670 2 875.474417 438.7445 Phosphatidylinositol transfer protein beta isoform OS=Homo sapiens OX=9606 GN=PITPNB PE=1 SV=2 8.75 2570.8 - 448264 - - - -0.08 - 1.318 0.167 - 116.5 1 2 0 -0.0001 8 0 0 0 3.68E+07 2.10E+07 - - - 1.1072 0.9742 221125_WJC_METTL3_EV_vs_WT_F02.11671.11671.2 0.00733 18-Aug R.IYQGTLGAIK[136.11].V sp|Q9NRL2|BAZ1A_HUMAN 1 1070.6215 0.76 12578 11671 2 1070.627789 536.318 Bromodomain adjacent to zinc finger domain protein 1A OS=Homo sapiens OX=9606 GN=BAZ1A PE=1 SV=2 8.59 2571 - 551610 - - - 5.8312 - 1.393 0.36 - 121.6 1 2 0 0.0062 10 0 0 0 2.16E+07 2.83E+07 - - - 2.6232 0.9973 221125_WJC_METTL3_EV_vs_WT_F02.11678.11678.2 0.0262 18-Oct K.QSLPPGLAVK.E sp|P63173|RL38_HUMAN 1 1008.5968 1.12 12583 11678 2 1008.597384 505.3057 60S ribosomal protein L38 OS=Homo sapiens OX=9606 GN=RPL38 PE=1 SV=2 8.75 2571.8 - 394147 - - - 0.5979 - 1.517 0.196 - 256.7 1 2 0 0.0006 10 0 0 0 1.61E+08 1.44E+08 - - - 1.6517 0.9986 221125_WJC_METTL3_EV_vs_WT_F02.11682.11682.2 0.0405 16-Sep R.SVANPAFLK.A "sp|Q99567|NUP88_HUMAN,tr|I3L4K7|I3L4K7_HUMAN" 2 945.5284 2.06 12585 11682 2 945.528339 473.7715 Nuclear pore complex protein Nup88 OS=Homo sapiens OX=9606 GN=NUP88 PE=1 SV=2 8.47 2572.3 - 1.86E+06 - - - -0.0296 - 1.474 0.261 - 212.1 1 2 0 0 9 0 0 0 2.68E+08 1.30E+08 - - - 2.0912 0.9992 221125_WJC_METTL3_EV_vs_WT_F02.11683.11683.2 0.142 14-Aug K.VLELDNVK[136.11].S "sp|P30153|2AAA_HUMAN,tr|C9J9C1|C9J9C1_HUMAN,tr|B3KQV6|B3KQV6_HUMAN" 3 936.5371 0.82 12586 11683 2 936.536113 469.2758 Serine\threonine-protein phosphatase 2A 65 kDa regulatory subunit A alpha isoform OS=Homo sapiens OX=9606 GN=PPP2R1A PE=1 SV=4 4.37 2572.4 - 1.12E+06 - - - -1.1041 - 1.496 0.346 - 155.9 1 2 0 -0.001 8 0 0 0 3.54E+08 4.32E+08 - - - 2.811 1 221125_WJC_METTL3_EV_vs_WT_F02.11688.11688.2 4.58E-05 16-Nov K.SPLQSVVVR.R "sp|Q9Y2W1|TR150_HUMAN,tr|A0A3B3ITZ9|A0A3B3ITZ9_HUMAN" 2 983.5764 3.14 12590 11688 2 983.576645 492.7955 Thyroid hormone receptor-associated protein 3 OS=Homo sapiens OX=9606 GN=THRAP3 PE=1 SV=2 9.47 2573 - 1.57E+06 - - - 0.2694 - 2.397 0.581 - 521.1 1 2 0 0.0003 9 0 0 0 9.42E+07 3.00E+07 - - - 5.8613 0.9976 221125_WJC_METTL3_EV_vs_WT_F02.11689.11689.2 0.0427 14-Jul K.YETELNLR.M sp|P02533|K1C14_HUMAN 1 1036.5189 4.69 12591 11689 2 1036.519858 519.2667 "Keratin, type I cytoskeletal 14 OS=Homo sapiens OX=9606 GN=KRT14 PE=1 SV=4" 4.53 2573.1 - 1.76E+06 - - - 0.9001 - 1.511 0.21 - 127.6 1 2 0 0.0009 8 0 0 0 2.00E+08 4.27E+07 - - - 1.8367 0.9763 221125_WJC_METTL3_EV_vs_WT_F02.11690.11690.2 0.00211 16-Oct R.YPDGIISK[136.11]P.K sp|Q86U44|MTA70_HUMAN 1 996.5371 0.03 12592 11690 2 996.536892 499.2758 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 5.83 2573.2 - 3.85E+06 - - - -0.2559 - 1.72 0.356 - 255.9 1 1 0 -0.0003 9 0 0 0 1.88E+07 6.83E+08 - - - 3.2393 0.9919 221125_WJC_METTL3_EV_vs_WT_F02.11692.11692.2 0.543 16-Aug R.SVANPAFLK[136.11].A "sp|Q99567|NUP88_HUMAN,tr|I3L4K7|I3L4K7_HUMAN" 2 953.5426 2.14 12594 11692 2 953.53942 477.7786 Nuclear pore complex protein Nup88 OS=Homo sapiens OX=9606 GN=NUP88 PE=1 SV=2 8.47 2573.3 - 1.11E+06 - - - -3.3003 - 1.542 0.238 - 161.2 1 2 0 -0.0031 9 0 0 0 2.78E+08 1.30E+08 - - - 2.0508 0.9923 221125_WJC_METTL3_EV_vs_WT_F02.11693.11693.2 0.0522 12-Jul K.GFGAFER.S "sp|Q9NY61|AATF_HUMAN,tr|A0A7P0T868|A0A7P0T868_HUMAN,tr|A0A7P0TAR0|A0A7P0TAR0_HUMAN,tr|A0A087WWS8|A0A087WWS8_HUMAN,tr|A0A7P0TBI0|A0A7P0TBI0_HUMAN,tr|A0A7P0Z4P2|A0A7P0Z4P2_HUMAN,tr|A0A7P0Z4N2|A0A7P0Z4N2_HUMAN,tr|A0A087WTH8|A0A087WTH8_HUMAN,tr|A0A7P0Z434|A0A7P0Z434_HUMAN" 9 782.3711 1.22 12595 11693 2 782.371787 392.1928 Protein AATF OS=Homo sapiens OX=9606 GN=AATF PE=1 SV=1 6 2573.3 - 1.72E+06 - - - 0.8295 - 1.138 0.202 - 174.8 1 2 0 0.0006 7 0 0 0 2.77E+07 2.26E+07 - - - 0.9424 0.9966 221125_WJC_METTL3_EV_vs_WT_F02.11694.11694.2 0.244 14-Jul R.LMEIYQEK.L sp|Q92616|GCN1_HUMAN 1 1052.5212 1.5 12596 11694 2 1052.521368 527.2679 eIF-2-alpha kinase activator GCN1 OS=Homo sapiens OX=9606 GN=GCN1 PE=1 SV=6 4.53 2573.5 - 740296 - - - 0.1283 - 1.269 0.222 - 113.6 1 2 0 0.0001 8 0 0 0 2.15E+07 1.43E+07 - - - 1.3991 0.9999 221125_WJC_METTL3_EV_vs_WT_F02.11695.11695.2 9.72E-07 26-Dec K.LLPAAGPAGGEPYR[166.11].L "sp|O60934|NBN_HUMAN,tr|E2QRP0|E2QRP0_HUMAN,tr|E5RGU1|E5RGU1_HUMAN" 3 1377.728 1.29 12597 11695 2 1377.726912 689.8713 Nibrin OS=Homo sapiens OX=9606 GN=NBN PE=1 SV=1 6 2573.6 - 367125 - - - -0.8042 - 2.147 0.586 - 419.3 1 2 0 -0.0011 14 0 0 0 2.34E+07 1.81E+07 - - - 5.2862 0.9975 221125_WJC_METTL3_EV_vs_WT_F02.11698.11698.2 0.0625 14-Jun R.FPNK[136.11]PYLS.- sp|Q96BP2|CHCH1_HUMAN 1 972.516 1.42 12598 11698 2 972.517351 487.2653 Coiled-coil-helix-coiled-coil-helix domain-containing protein 1 OS=Homo sapiens OX=9606 GN=CHCHD1 PE=1 SV=1 8.59 2574 - 5.21E+06 - - - 1.3707 - 1.201 0.325 - 77 1 2 0 0.0013 8 0 0 0 1.64E+09 1.15E+09 - - - 1.9934 0.9998 221125_WJC_METTL3_EV_vs_WT_F02.11700.11700.2 0.00992 16-Nov K.TLETVPLER.K "sp|P22626|ROA2_HUMAN,tr|A0A7I2V4I6|A0A7I2V4I6_HUMAN,tr|A0A087WUI2|A0A087WUI2_HUMAN" 3 1056.5815 1.46 12600 11700 2 1056.582063 529.298 Heterogeneous nuclear ribonucleoproteins A2\B1 OS=Homo sapiens OX=9606 GN=HNRNPA2B1 PE=1 SV=2 4.53 2574.1 - 1.72E+06 - - - 0.5092 - 2.167 0.392 - 384.9 1 2 0 0.0005 9 0 0 0 2.33E+09 1.60E+09 - - - 4.1735 0.9997 221125_WJC_METTL3_EV_vs_WT_F02.11701.11701.2 0.00172 16-Oct K.TLETVPLER[166.11].K "sp|P22626|ROA2_HUMAN,tr|A0A7I2V4I6|A0A7I2V4I6_HUMAN,tr|A0A087WUI2|A0A087WUI2_HUMAN" 3 1066.5898 1.46 12601 11701 2 1066.591186 534.3022 Heterogeneous nuclear ribonucleoproteins A2\B1 OS=Homo sapiens OX=9606 GN=HNRNPA2B1 PE=1 SV=2 4.53 2574.3 - 1.64E+06 - - - 1.3042 - 1.754 0.451 - 306 1 2 0 0.0014 9 0 0 0 2.33E+09 1.60E+09 - - - 3.9973 0.9932 221125_WJC_METTL3_EV_vs_WT_F02.11702.11702.2 0.153 16-Jul K.MIGFSETAK[136.11].C "sp|P46459|NSF_HUMAN,tr|I3L0N3|I3L0N3_HUMAN,tr|I3L2G1|I3L2G1_HUMAN" 3 990.4936 1.28 12602 11702 2 990.49409 496.2541 Vesicle-fusing ATPase OS=Homo sapiens OX=9606 GN=NSF PE=1 SV=3 5.75 2574.3 - 859550 - - - 0.527 - 1.111 0.217 - 94.2 1 2 0 0.0005 9 0 0 0 1.56E+07 1.21E+07 - - - 0.9481 0.9999 221125_WJC_METTL3_EV_vs_WT_F02.11704.11704.2 1.21E-06 20-Sep K.VVEGTPLIDGR.R "sp|Q14739|LBR_HUMAN,tr|A0A494C1L1|A0A494C1L1_HUMAN" 2 1154.6295 1.21 12604 11704 2 1154.630064 578.322 Delta(14)-sterol reductase LBR OS=Homo sapiens OX=9606 GN=LBR PE=1 SV=2 4.37 2574.6 - 511059 - - - 0.4556 - 2.061 0.563 - 237.2 1 2 0 0.0005 11 0 0 0 3.25E+07 2.68E+07 - - - 5.1556 0.9996 221125_WJC_METTL3_EV_vs_WT_F02.11705.11705.2 0.000314 26-Nov K.LLPAAGPAGGEPYR.L "sp|O60934|NBN_HUMAN,tr|E2QRP0|E2QRP0_HUMAN,tr|E5RGU1|E5RGU1_HUMAN" 3 1367.7197 1.29 12605 11705 2 1367.722613 684.8672 Nibrin OS=Homo sapiens OX=9606 GN=NBN PE=1 SV=1 6 2574.7 - 313634 - - - 2.0933 - 2.103 0.467 - 358.2 1 2 0 0.0029 14 0 0 0 2.34E+07 1.81E+07 - - - 4.3548 0.999 221125_WJC_METTL3_EV_vs_WT_F02.11708.11708.2 0.00735 12-Jun K.AYADFYR.N sp|P09669|COX6C_HUMAN 1 904.4079 0.95 12606 11708 2 904.407823 453.2112 Cytochrome c oxidase subunit 6C OS=Homo sapiens OX=9606 GN=COX6C PE=1 SV=2 5.88 2575.1 - 1.08E+06 - - - -0.105 - 1.203 0.372 - 138.5 1 2 0 -0.0001 7 0 0 0 8.39E+07 8.82E+07 - - - 2.3742 0.8906 221125_WJC_METTL3_EV_vs_WT_F02.11710.11710.2 6.59 12-May K.LNYLDPR.L "sp|P11387|TOP1_HUMAN,sp|Q969P6|TOP1M_HUMAN,tr|H0YAR3|H0YAR3_HUMAN,tr|A0A7P0T852|A0A7P0T852_HUMAN" 4 889.4658 1.07 12608 11710 2 889.465577 445.7402 DNA topoisomerase 1 OS=Homo sapiens OX=9606 GN=TOP1 PE=1 SV=2 5.84 2575.3 - 676726 - - - -0.2136 - 0.997 0.001 - 83.8 1 2 0 -0.0002 7 0 0 0 8.09E+07 7.53E+07 - - - -0.9612 0.9986 221125_WJC_METTL3_EV_vs_WT_F02.11711.11711.2 0.00804 20-Sep K.VVEGTPLIDGR[166.11].R "sp|Q14739|LBR_HUMAN,tr|A0A494C1L1|A0A494C1L1_HUMAN" 2 1164.6378 1.22 12609 11711 2 1164.639541 583.3262 Delta(14)-sterol reductase LBR OS=Homo sapiens OX=9606 GN=LBR PE=1 SV=2 4.37 2575.4 - 504729 - - - 1.488 - 1.677 0.289 - 324.3 1 2 0 0.0017 11 0 0 0 3.20E+07 2.63E+07 - - - 2.5736 0.9961 221125_WJC_METTL3_EV_vs_WT_F02.11712.11712.2 0.104 20-Aug K.TPGSLGDPVLK.R sp|Q96AV8|E2F7_HUMAN 1 1082.5972 53.67 12610 11712 2 1082.598744 542.3059 Transcription factor E2F7 OS=Homo sapiens OX=9606 GN=E2F7 PE=1 SV=3 5.5 2575.5 - 446463 - - - 1.4493 - 1.183 0.293 - 120.6 1 2 0 0.0016 11 0 0 0 3.05E+08 5.69E+06 - - - 1.6592 0.9963 221125_WJC_METTL3_EV_vs_WT_F02.11716.11716.2 0.191 12-Jun K.AYADFYR[166.11].N sp|P09669|COX6C_HUMAN 1 914.4162 0.95 12612 11716 2 914.416298 458.2154 Cytochrome c oxidase subunit 6C OS=Homo sapiens OX=9606 GN=COX6C PE=1 SV=2 5.88 2576 - 2.09E+06 - - - 0.1203 - 1.182 0.239 - 142.4 1 2 0 0.0001 7 0 0 0 8.41E+07 8.82E+07 - - - 1.336 0.9907 221125_WJC_METTL3_EV_vs_WT_F02.11717.11717.2 1.74 16-Aug K.DIEEASLVK[136.11].V "sp|P07197|NFM_HUMAN,tr|E7ESP9|E7ESP9_HUMAN,tr|E7EMV2|E7EMV2_HUMAN" 3 1010.5375 2.4 12613 11717 2 1010.537699 506.276 Neurofilament medium polypeptide OS=Homo sapiens OX=9606 GN=NEFM PE=1 SV=3 4.14 2576.1 - 1.64E+06 - - - 0.1564 - 1.149 0.167 - 143.5 1 2 0 0.0002 9 0 0 0 1.84E+08 7.68E+07 - - - 0.6762 0.9864 221125_WJC_METTL3_EV_vs_WT_F02.11718.11718.2 0.468 18-Oct R.SPEVLLGSAR.Y "sp|P06493|CDK1_HUMAN,tr|E5RIU6|E5RIU6_HUMAN,tr|A0A024QZP7|A0A024QZP7_HUMAN,tr|A0A087WZZ9|A0A087WZZ9_HUMAN" 4 1027.5662 1.03 12614 11718 2 1027.572039 514.7904 Cyclin-dependent kinase 1 OS=Homo sapiens OX=9606 GN=CDK1 PE=1 SV=3 5.72 2576.2 - 1.21E+06 - - - 5.6736 - 1.951 0.305 - 240.2 1 2 0 0.0058 10 0 0 0 2.76E+07 2.67E+07 - - - 3.1574 0.9974 221125_WJC_METTL3_EV_vs_WT_F02.11721.11721.2 0.00887 14-Sep R.SPALQVLR.E sp|Q96EY7|PTCD3_HUMAN 1 882.5287 1.2 12615 11721 2 882.526501 442.2716 "Pentatricopeptide repeat domain-containing protein 3, mitochondrial OS=Homo sapiens OX=9606 GN=PTCD3 PE=1 SV=3" 9.47 2576.6 - 1.66E+06 - - - -2.4928 - 1.796 0.23 - 323.8 1 2 0 -0.0022 8 0 0 0 5.51E+07 4.59E+07 - - - 2.5051 0.9825 221125_WJC_METTL3_EV_vs_WT_F02.11723.11723.2 2.27 12-Jul K.LGITQLR[166.11].F "sp|Q9Y285|SYFA_HUMAN,tr|K7EPH2|K7EPH2_HUMAN,tr|K7ER00|K7ER00_HUMAN" 3 809.4999 1.43 12617 11723 2 809.500017 405.7572 Phenylalanine--tRNA ligase alpha subunit OS=Homo sapiens OX=9606 GN=FARSA PE=1 SV=3 9.75 2576.8 - 657103 - - - 0.1964 - 1.468 0 - 122 1 2 0 0.0002 7 0 0 0 1.55E+08 1.08E+08 - - - 0.2574 0.9991 221125_WJC_METTL3_EV_vs_WT_F02.11728.11728.2 0.04 18-Aug K.QSLPPGLAVK[136.11].E sp|P63173|RL38_HUMAN 1 1016.611 1.12 12620 11728 2 1016.611479 509.3128 60S ribosomal protein L38 OS=Homo sapiens OX=9606 GN=RPL38 PE=1 SV=2 8.75 2577.5 - 1.61E+06 - - - 0.4899 - 1.603 0.297 - 205.3 1 2 0 0.0005 10 0 0 0 1.61E+08 1.44E+08 - - - 2.5516 0.9991 221125_WJC_METTL3_EV_vs_WT_F02.11730.11730.2 0.000264 22-Nov K.NAGVEGSLIVEK.L "sp|P10809|CH60_HUMAN,tr|A0A7I2V2X6|A0A7I2V2X6_HUMAN,tr|A0A7I2YQK6|A0A7I2YQK6_HUMAN,tr|A0A7I2V599|A0A7I2V599_HUMAN" 4 1214.6507 1.45 12622 11730 2 1214.64782 608.3326 "60 kDa heat shock protein, mitochondrial OS=Homo sapiens OX=9606 GN=HSPD1 PE=1 SV=2" 4.53 2577.6 - 403823 - - - -2.3439 - 1.77 0.392 - 344.5 1 2 0 -0.0028 12 0 0 0 1.74E+08 1.20E+08 - - - 3.4378 0.9854 221125_WJC_METTL3_EV_vs_WT_F02.11733.11733.2 0.00617 14-Jun R.EVFEMATR[166.11].A "sp|P61586|RHOA_HUMAN,sp|P08134|RHOC_HUMAN,tr|Q5JR08|Q5JR08_HUMAN,tr|A0A7I2YQV1|A0A7I2YQV1_HUMAN" 4 991.4672 0.88 12623 11733 2 991.464762 496.7409 Transforming protein RhoA OS=Homo sapiens OX=9606 GN=RHOA PE=1 SV=1 4.53 2578 - 1.34E+06 - - - -2.4963 - 1.299 0.177 - 124 1 2 0 -0.0025 8 0 0 0 1.38E+08 1.57E+08 - - - 1.1365 0.9995 221125_WJC_METTL3_EV_vs_WT_F02.11734.11734.2 0.00011 22-Nov K.NAGVEGSLIVEK[136.11].L "sp|P10809|CH60_HUMAN,tr|A0A7I2V2X6|A0A7I2V2X6_HUMAN,tr|A0A7I2YQK6|A0A7I2YQK6_HUMAN,tr|A0A7I2V599|A0A7I2V599_HUMAN" 4 1222.6649 1.45 12624 11734 2 1222.661338 612.3397 "60 kDa heat shock protein, mitochondrial OS=Homo sapiens OX=9606 GN=HSPD1 PE=1 SV=2" 4.53 2578.2 - 643144 - - - -2.8863 - 2.202 0.489 - 300.4 1 2 0 -0.0035 12 0 0 0 1.74E+08 1.20E+08 - - - 4.7286 0.9981 221125_WJC_METTL3_EV_vs_WT_F02.11735.11735.2 0.0334 14-Jul K.IGVTVLSR[166.11].L "sp|P16152|CBR1_HUMAN,sp|O75828|CBR3_HUMAN" 2 853.5261 1.08 12625 11735 2 853.526786 427.7703 Carbonyl reductase [NADPH] 1 OS=Homo sapiens OX=9606 GN=CBR1 PE=1 SV=3 9.75 2578.2 - 4.76E+06 - - - 0.8365 - 1.679 0.191 - 146 1 2 0 0.0007 8 0 0 0 2.57E+08 2.37E+08 - - - 2.0144 0.9728 221125_WJC_METTL3_EV_vs_WT_F02.11738.11738.2 0.162 12-Jul R.LMDLLSK[136.11].K "sp|Q8IZ52|CHSS2_HUMAN,sp|Q8NEV4|MYO3A_HUMAN,sp|Q8WXR4|MYO3B_HUMAN,tr|F5H2J1|F5H2J1_HUMAN" 4 826.4714 0.85 12626 11738 2 826.471732 414.243 Chondroitin sulfate synthase 2 OS=Homo sapiens OX=9606 GN=CHPF PE=1 SV=2 5.84 2578.6 - 1.02E+07 - - - 0.4307 - 1.409 0.001 - 202.4 2 2 0 0.0004 7 0 0 0 4.07E+09 4.78E+09 - - - 0.0002 0.996 221125_WJC_METTL3_EV_vs_WT_F02.11739.11739.2 3.32 12-Jul R.LELAEMK.E "sp|Q99417|MYCBP_HUMAN,tr|A0A087WV05|A0A087WV05_HUMAN" 2 832.4364 1.42 12627 11739 2 832.436628 417.2255 c-Myc-binding protein OS=Homo sapiens OX=9606 GN=MYCBP PE=1 SV=3 4.53 2578.6 - 8.04E+06 - - - 0.2258 - 1.447 0.144 - 161.9 1 2 0 0.0002 7 0 0 0 1.86E+08 1.30E+08 - - - 1.2753 0.8637 221125_WJC_METTL3_EV_vs_WT_F02.11741.11741.2 4.06 12-Apr K.VAFSAIR.S "sp|P23435|CBLN1_HUMAN,tr|H3BQD0|H3BQD0_HUMAN" 2 762.4388 0.33 12629 11741 2 762.43953 382.2267 Cerebellin-1 OS=Homo sapiens OX=9606 GN=CBLN1 PE=1 SV=1 9.72 2578.8 - 724272 - - - 0.926 - 1.115 0.033 - 47.4 21 2 0 0.0007 7 0 0 0 2.17E+07 6.65E+07 - - - -0.9612 0.8779 221125_WJC_METTL3_EV_vs_WT_F02.11743.11743.2 2.83 12-Jun K.LMVELSK.S "sp|P48643|TCPE_HUMAN,tr|E9PCA1|E9PCA1_HUMAN,tr|B7ZAR1|B7ZAR1_HUMAN" 3 818.4572 0.85 12630 11743 2 818.459779 410.2359 T-complex protein 1 subunit epsilon OS=Homo sapiens OX=9606 GN=CCT5 PE=1 SV=1 6 2579 - 7.08E+06 - - - 3.1804 - 1.264 0.057 - 142.6 3 2 0 0.0026 7 0 0 0 4.07E+09 4.78E+09 - - - -0.0096 0.9992 221125_WJC_METTL3_EV_vs_WT_F02.11745.11745.2 0.00484 14-Aug K.IGVTVLSR.L "sp|P16152|CBR1_HUMAN,sp|O75828|CBR3_HUMAN" 2 843.5178 1.09 12631 11745 2 843.518047 422.7662 Carbonyl reductase [NADPH] 1 OS=Homo sapiens OX=9606 GN=CBR1 PE=1 SV=3 9.75 2579.2 - 7.82E+06 - - - 0.2905 - 1.706 0.269 - 186.2 1 2 0 0.0002 8 0 0 0 2.57E+08 2.36E+08 - - - 2.6387 0.9983 221125_WJC_METTL3_EV_vs_WT_F02.11746.11746.2 0.000492 14-Jul R.EVFEMATR.A "sp|P61586|RHOA_HUMAN,sp|P08134|RHOC_HUMAN,tr|Q5JR08|Q5JR08_HUMAN,tr|A0A7I2YQV1|A0A7I2YQV1_HUMAN" 4 981.459 0.89 12632 11746 2 981.459505 491.7368 Transforming protein RhoA OS=Homo sapiens OX=9606 GN=RHOA PE=1 SV=1 4.53 2579.3 - 2.20E+06 - - - 0.5482 - 1.449 0.253 - 210.7 1 2 0 0.0005 8 0 0 0 1.38E+08 1.54E+08 - - - 2.028 0.964 221125_WJC_METTL3_EV_vs_WT_F02.11747.11747.2 0.0043 16-Sep R.ELLTTMGDR[166.11].F "sp|O14950|ML12B_HUMAN,sp|P19105|ML12A_HUMAN,sp|P24844|MYL9_HUMAN,tr|J3QRS3|J3QRS3_HUMAN" 4 1044.5149 1.22 12633 11747 2 1044.523398 523.2647 Myosin regulatory light chain 12B OS=Homo sapiens OX=9606 GN=MYL12B PE=1 SV=2 4.37 2579.4 - 1.94E+06 - - - 8.1215 - 1.779 0.37 - 360.3 1 2 0 0.0085 9 0 0 0 3.27E+08 2.68E+08 - - - 3.4377 0.9998 221125_WJC_METTL3_EV_vs_WT_F02.11750.11750.2 0.000119 20-Oct K.LSAMMGAVAEK.K "sp|Q86U44|MTA70_HUMAN,tr|F5H6D8|F5H6D8_HUMAN,tr|H0YFV6|H0YFV6_HUMAN,tr|B4DTN4|B4DTN4_HUMAN" 4 1106.5464 0.02 12635 11750 2 1106.547842 554.2805 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 6 2579.7 - 1.48E+06 - - - 1.3013 - 2.147 0.488 - 272.8 1 2 0 0.0014 11 0 0 0 8.28E+07 3.81E+09 - - - 4.7119 0.9992 221125_WJC_METTL3_EV_vs_WT_F02.11752.11752.3 0.105 Nov-32 K.LLPLEEHYR.F "sp|Q9NZN3|EHD3_HUMAN,sp|Q9NZN4|EHD2_HUMAN,sp|Q9H4M9|EHD1_HUMAN,tr|C9JC03|C9JC03_HUMAN,tr|C9JIJ3|C9JIJ3_HUMAN,tr|C9IZH1|C9IZH1_HUMAN,tr|A0A024R571|A0A024R571_HUMAN" 7 1168.6241 1.26 12636 11752 3 1168.624358 390.5486 EH domain-containing protein 3 OS=Homo sapiens OX=9606 GN=EHD3 PE=1 SV=2 5.4 2579.9 - 2.56E+06 - - - 0.2567 - 1.946 0.262 - 155 1 2 0 0.0003 9 0 0 0 5.91E+07 4.69E+07 - - - 3.4675 0.9977 221125_WJC_METTL3_EV_vs_WT_F02.11753.11753.2 0.0341 16-Aug K.LLPLEEHYR.F "sp|Q9NZN3|EHD3_HUMAN,sp|Q9NZN4|EHD2_HUMAN,sp|Q9H4M9|EHD1_HUMAN,tr|C9JC03|C9JC03_HUMAN,tr|C9JIJ3|C9JIJ3_HUMAN,tr|C9IZH1|C9IZH1_HUMAN,tr|A0A024R571|A0A024R571_HUMAN" 7 1168.6241 3.29 12637 11753 2 1168.623977 585.3193 EH domain-containing protein 3 OS=Homo sapiens OX=9606 GN=EHD3 PE=1 SV=2 5.4 2580.1 - 327351 - - - -0.0693 - 1.41 0.224 - 160.1 1 2 0 -0.0001 9 0 0 0 8.83E+06 2.69E+06 - - - 1.6895 0.9628 221125_WJC_METTL3_EV_vs_WT_F02.11764.11764.2 9.57 12-Jul K.LGITQLR.F "sp|Q9Y285|SYFA_HUMAN,tr|K7EPH2|K7EPH2_HUMAN,tr|K7ER00|K7ER00_HUMAN" 3 799.4916 1.44 12641 11764 2 799.490111 400.7531 Phenylalanine--tRNA ligase alpha subunit OS=Homo sapiens OX=9606 GN=FARSA PE=1 SV=3 9.75 2581.5 - 4.39E+06 - - - -1.8474 - 1.427 0.001 - 126.2 1 2 0 -0.0015 7 0 0 0 1.55E+08 1.08E+08 - - - 0.1746 0.993 221125_WJC_METTL3_EV_vs_WT_F02.11771.11771.2 0.821 12-Jun R.AIETLIK.N "sp|Q9HCY8|S10AE_HUMAN,sp|Q9Y485|DMXL1_HUMAN,tr|F5H269|F5H269_HUMAN" 3 786.4851 42.66 12646 11771 2 786.48554 394.2498 Protein S100-A14 OS=Homo sapiens OX=9606 GN=S100A14 PE=1 SV=1 6.05 2582.2 - 3.79E+06 - - - 0.5531 - 1.195 0.18 - 100.4 1 2 0 0.0004 7 0 0 0 1.37E+08 3.21E+06 - - - 0.9348 0.9988 221125_WJC_METTL3_EV_vs_WT_F02.11775.11775.2 0.0715 18-Aug R.LTDEQVALVR.R "sp|Q14137|BOP1_HUMAN,tr|A0A075B729|A0A075B729_HUMAN" 2 1142.6295 0.94 12650 11775 2 1142.628093 572.322 Ribosome biogenesis protein BOP1 OS=Homo sapiens OX=9606 GN=BOP1 PE=1 SV=2 4.37 2582.5 - 306702 - - - -1.2646 - 1.568 0.297 - 123.2 1 2 0 -0.0014 10 0 0 0 6.67E+07 7.09E+07 - - - 2.4897 0.9978 221125_WJC_METTL3_EV_vs_WT_F02.11778.11778.2 0.013 16-Aug R.ELLTTMGDR.F "sp|O14950|ML12B_HUMAN,sp|P19105|ML12A_HUMAN,sp|P24844|MYL9_HUMAN,tr|J3QRS3|J3QRS3_HUMAN" 4 1034.5066 1.23 12651 11778 2 1034.509395 518.2606 Myosin regulatory light chain 12B OS=Homo sapiens OX=9606 GN=MYL12B PE=1 SV=2 4.37 2582.9 - 4.83E+06 - - - 2.6583 - 1.61 0.325 - 288.7 1 2 0 0.0027 9 0 0 0 3.27E+08 2.66E+08 - - - 2.8184 0.999 221125_WJC_METTL3_EV_vs_WT_F02.11782.11782.2 0.194 12-Jul K.DDAMLLK[136.11].G "sp|P10809|CH60_HUMAN,tr|A0A7I2V2X6|A0A7I2V2X6_HUMAN,tr|A0A7I2YQK6|A0A7I2YQK6_HUMAN,tr|A0A7I2V599|A0A7I2V599_HUMAN" 4 812.4193 1.25 12653 11782 2 812.419068 407.2169 "60 kDa heat shock protein, mitochondrial OS=Homo sapiens OX=9606 GN=HSPD1 PE=1 SV=2" 4.21 2583.4 - 4.59E+06 - - - -0.3348 - 1.62 0.25 - 329.6 1 2 0 -0.0003 7 0 0 0 8.98E+09 7.21E+09 - - - 2.416 1 221125_WJC_METTL3_EV_vs_WT_F02.11785.11785.2 3.14E-06 20-Nov K.ILYSQC[160.03]GDVMR[166.11].A "sp|P14649|MYL6B_HUMAN,sp|P60660|MYL6_HUMAN,tr|F8W1R7|F8W1R7_HUMAN,tr|G3V1V0|G3V1V0_HUMAN,tr|B7Z6Z4|B7Z6Z4_HUMAN,tr|G8JLA2|G8JLA2_HUMAN,tr|F8W1I5|F8W1I5_HUMAN,tr|J3KND3|J3KND3_HUMAN,tr|F8VPF3|F8VPF3_HUMAN" 9 1350.63 1.3 12656 11785 2 1350.631921 676.3223 Myosin light chain 6B OS=Homo sapiens OX=9606 GN=MYL6B PE=1 SV=1 5.83 2583.8 - 224730 - - - 1.4504 - 2.048 0.651 - 384.2 1 2 0 0.002 11 0 0 0 1.31E+08 1.01E+08 - - - 5.788 0.8236 221125_WJC_METTL3_EV_vs_WT_F02.11788.11788.2 0.057 12-Jul N.FSSLNLR[166.11].E "sp|P08670|VIME_HUMAN,tr|B0YJC4|B0YJC4_HUMAN" 2 845.4635 1.72 12657 11788 2 845.463175 423.739 Vimentin OS=Homo sapiens OX=9606 GN=VIM PE=1 SV=4 9.75 2584.2 - 8.71E+06 - - - -0.3513 - 1.526 0.132 - 144.5 1 1 0 -0.0003 7 0 0 0 3.87E+08 2.25E+08 - - - 1.355 0.9998 221125_WJC_METTL3_EV_vs_WT_F02.11792.11792.2 0.000376 14-Aug M.PTVEELYR.N "sp|Q9BZZ5|API5_HUMAN,tr|E9PQK6|E9PQK6_HUMAN,tr|G3V1C3|G3V1C3_HUMAN" 3 1005.5131 2.42 12659 11792 2 1005.513039 503.7638 Apoptosis inhibitor 5 OS=Homo sapiens OX=9606 GN=API5 PE=1 SV=3 4.53 2584.6 - 4.59E+06 - - - -0.0716 - 1.835 0.48 - 233.3 1 2 0 -0.0001 8 0 0 0 3.36E+08 1.39E+08 - - - 4.4171 0.9993 221125_WJC_METTL3_EV_vs_WT_F02.11794.11794.2 0.0057 16-Jun K.YLVMDEADR[166.11].L "sp|Q9H0S4|DDX47_HUMAN,tr|F5H1N9|F5H1N9_HUMAN" 2 1120.5098 0.69 12661 11794 2 1120.509282 561.2622 Probable ATP-dependent RNA helicase DDX47 OS=Homo sapiens OX=9606 GN=DDX47 PE=1 SV=1 4.03 2584.8 - 2.59E+06 - - - -0.4891 - 1.421 0.368 - 80.5 1 2 0 -0.0005 9 0 0 0 2.81E+07 4.10E+07 - - - 2.7754 0.9984 221125_WJC_METTL3_EV_vs_WT_F02.11798.11798.2 0.143 14-Sep K.APGLGAFR.R sp|P78527|PRKDC_HUMAN 1 787.4341 0.99 12663 11798 2 787.433045 394.7243 DNA-dependent protein kinase catalytic subunit OS=Homo sapiens OX=9606 GN=PRKDC PE=1 SV=3 9.79 2585.4 - 2.55E+06 - - - -1.3055 - 1.364 0.308 - 201.5 1 2 0 -0.001 8 0 0 0 9.85E+07 1.00E+08 - - - 2.2518 0.9442 221125_WJC_METTL3_EV_vs_WT_F02.11801.11801.2 0.0148 14-Sep K.LTGVFAPR.P "sp|P62701|RS4X_HUMAN,sp|P22090|RS4Y1_HUMAN,sp|Q8TD47|RS4Y2_HUMAN,tr|C9JEH7|C9JEH7_HUMAN" 4 859.4916 1.02 12664 11801 2 859.490711 430.7531 "40S ribosomal protein S4, X isoform OS=Homo sapiens OX=9606 GN=RPS4X PE=1 SV=2" 9.75 2585.8 - 5.18E+06 - - - -1.0204 - 1.542 0.299 - 279 1 1 0 -0.0009 8 0 0 0 9.22E+08 9.04E+08 - - - 2.5553 0.9993 221125_WJC_METTL3_EV_vs_WT_F02.11802.11802.2 0.00618 16-Aug R.QFAALVASK[136.11].V "sp|Q99460|PSMD1_HUMAN,tr|A0A7I2V4X0|A0A7I2V4X0_HUMAN,tr|A0A7I2V2K8|A0A7I2V2K8_HUMAN,tr|A0A7I2YQY1|A0A7I2YQY1_HUMAN,tr|A0A7I2V523|A0A7I2V523_HUMAN,tr|A0A7I2V491|A0A7I2V491_HUMAN,tr|A0A7I2YQI9|A0A7I2YQI9_HUMAN,tr|C9J9M4|C9J9M4_HUMAN,tr|A0A7I2V262|A0A7I2V262_HUMAN,tr|A0A087WW66|A0A087WW66_HUMAN,tr|A0A7P0MW50|A0A7P0MW50_HUMAN,tr|A0A7I2V4A5|A0A7I2V4A5_HUMAN,tr|A0A7I2V5C8|A0A7I2V5C8_HUMAN,tr|A0A7I2V479|A0A7I2V479_HUMAN" 14 941.5426 0.75 12665 11802 2 941.541911 471.7786 26S proteasome non-ATPase regulatory subunit 1 OS=Homo sapiens OX=9606 GN=PSMD1 PE=1 SV=2 8.75 2585.9 - 1.84E+06 - - - -0.6967 - 1.778 0.27 - 308.1 1 2 0 -0.0007 9 0 0 0 6.12E+07 8.15E+07 - - - 2.6999 0.9743 221125_WJC_METTL3_EV_vs_WT_F02.11803.11803.2 0.00783 14-Sep K.LTGVFAPR[166.11].P "sp|P62701|RS4X_HUMAN,sp|P22090|RS4Y1_HUMAN,sp|Q8TD47|RS4Y2_HUMAN,tr|C9JEH7|C9JEH7_HUMAN" 4 869.4999 1.03 12666 11803 2 869.498793 435.7572 "40S ribosomal protein S4, X isoform OS=Homo sapiens OX=9606 GN=RPS4X PE=1 SV=2" 9.75 2585.9 - 6.98E+06 - - - -1.2248 - 1.665 0.391 - 293.6 1 1 0 -0.0011 8 0 0 0 9.36E+08 9.12E+08 - - - 3.4662 0.9999 221125_WJC_METTL3_EV_vs_WT_F02.11804.11804.2 7.18E-05 20-Dec K.ILYSQC[160.03]GDVMR.A "sp|P14649|MYL6B_HUMAN,sp|P60660|MYL6_HUMAN,tr|F8W1R7|F8W1R7_HUMAN,tr|G3V1V0|G3V1V0_HUMAN,tr|B7Z6Z4|B7Z6Z4_HUMAN,tr|G8JLA2|G8JLA2_HUMAN,tr|F8W1I5|F8W1I5_HUMAN,tr|J3KND3|J3KND3_HUMAN,tr|F8VPF3|F8VPF3_HUMAN" 9 1340.6217 1.31 12667 11804 2 1340.620813 671.3181 Myosin light chain 6B OS=Homo sapiens OX=9606 GN=MYL6B PE=1 SV=1 5.83 2586 - 1.11E+06 - - - -0.6557 - 2.072 0.629 - 370.4 1 2 0 -0.0009 11 0 0 0 1.32E+08 1.01E+08 - - - 5.6573 0.9993 221125_WJC_METTL3_EV_vs_WT_F02.11808.11808.2 0.00425 16-Sep R.QFAALVASK.V "sp|Q99460|PSMD1_HUMAN,tr|A0A7I2V4X0|A0A7I2V4X0_HUMAN,tr|A0A7I2V2K8|A0A7I2V2K8_HUMAN,tr|A0A7I2YQY1|A0A7I2YQY1_HUMAN,tr|A0A7I2V523|A0A7I2V523_HUMAN,tr|A0A7I2V491|A0A7I2V491_HUMAN,tr|A0A7I2YQI9|A0A7I2YQI9_HUMAN,tr|C9J9M4|C9J9M4_HUMAN,tr|A0A7I2V262|A0A7I2V262_HUMAN,tr|A0A087WW66|A0A087WW66_HUMAN,tr|A0A7P0MW50|A0A7P0MW50_HUMAN,tr|A0A7I2V4A5|A0A7I2V4A5_HUMAN,tr|A0A7I2V5C8|A0A7I2V5C8_HUMAN,tr|A0A7I2V479|A0A7I2V479_HUMAN" 14 933.5284 0.74 12669 11808 2 933.527295 467.7715 26S proteasome non-ATPase regulatory subunit 1 OS=Homo sapiens OX=9606 GN=PSMD1 PE=1 SV=2 8.75 2586.5 - 1.14E+06 - - - -1.1483 - 1.713 0.307 - 322 1 2 0 -0.0011 9 0 0 0 6.03E+07 8.10E+07 - - - 2.8653 0.9995 221125_WJC_METTL3_EV_vs_WT_F02.11813.11813.2 0.000154 20-Dec K.LVVLGSGGVGK[136.11].S "sp|P62834|RAP1A_HUMAN,sp|P61224|RAP1B_HUMAN,tr|F5H7Y6|F5H7Y6_HUMAN,tr|F5H500|F5H500_HUMAN,tr|E7ESV4|E7ESV4_HUMAN,tr|F5H491|F5H491_HUMAN,tr|F5GX62|F5GX62_HUMAN,tr|F5H4H0|F5H4H0_HUMAN,tr|F5H6R7|F5H6R7_HUMAN,tr|A0A075B6Q0|A0A075B6Q0_HUMAN,tr|F5H077|F5H077_HUMAN,tr|F8WBC0|F8WBC0_HUMAN,tr|F5H004|F5H004_HUMAN,tr|F5H0B7|F5H0B7_HUMAN,tr|F5GYB5|F5GYB5_HUMAN,tr|F5GWU8|F5GWU8_HUMAN,tr|F5GYH7|F5GYH7_HUMAN" 17 992.611 0.91 12672 11813 2 992.610054 497.3128 Ras-related protein Rap-1A OS=Homo sapiens OX=9606 GN=RAP1A PE=1 SV=1 8.75 2587.2 - 4.52E+06 - - - -0.9339 - 2.035 0.296 - 458.1 1 2 0 -0.0009 11 0 0 0 1.76E+08 1.93E+08 - - - 3.149 0.9997 221125_WJC_METTL3_EV_vs_WT_F02.11814.11814.2 0.00111 14-Sep M.PTVEELYR[166.11].N "sp|Q9BZZ5|API5_HUMAN,tr|E9PQK6|E9PQK6_HUMAN,tr|G3V1C3|G3V1C3_HUMAN" 3 1015.5214 2.41 12673 11814 2 1015.521877 508.768 Apoptosis inhibitor 5 OS=Homo sapiens OX=9606 GN=API5 PE=1 SV=3 4.53 2587.2 - 3.68E+06 - - - 0.4884 - 1.803 0.409 - 458.7 1 2 0 0.0005 8 0 0 0 3.36E+08 1.39E+08 - - - 3.8395 0.9996 221125_WJC_METTL3_EV_vs_WT_F02.11815.11815.2 0.00609 14-Jul K.SDPYALVR[166.11].L sp|Q9BSJ8|ESYT1_HUMAN 1 929.4846 1.64 12674 11815 2 929.484321 465.7496 Extended synaptotagmin-1 OS=Homo sapiens OX=9606 GN=ESYT1 PE=1 SV=1 5.55 2587.3 - 1.53E+06 - - - -0.3012 - 1.403 0.428 - 216.6 1 2 0 -0.0003 8 0 0 0 1.02E+08 6.24E+07 - - - 3.2234 0.9982 221125_WJC_METTL3_EV_vs_WT_F02.11819.11819.2 0.0496 16-Aug R.YPMAVGLNK.G "sp|Q9Y3U8|RL36_HUMAN,tr|J3KTD3|J3KTD3_HUMAN,tr|J3QSB5|J3QSB5_HUMAN" 3 991.5161 1.11 12676 11819 2 991.517275 496.7653 60S ribosomal protein L36 OS=Homo sapiens OX=9606 GN=RPL36 PE=1 SV=3 8.59 2587.8 - 4.02E+06 - - - 1.1972 - 1.636 0.23 - 207.6 1 2 0 0.0012 9 0 0 0 1.71E+08 1.54E+08 - - - 2.1635 0.9998 221125_WJC_METTL3_EV_vs_WT_F02.11821.11821.2 0.000161 18-Nov R.LTDEQVALVR[166.11].R "sp|Q14137|BOP1_HUMAN,tr|A0A075B729|A0A075B729_HUMAN" 2 1152.6378 0.94 12677 11821 2 1152.636454 577.3262 Ribosome biogenesis protein BOP1 OS=Homo sapiens OX=9606 GN=BOP1 PE=1 SV=2 4.37 2588 - 1.89E+06 - - - -1.1747 - 2.284 0.475 - 518.6 1 2 0 -0.0014 10 0 0 0 6.67E+07 7.09E+07 - - - 4.8543 0.9933 221125_WJC_METTL3_EV_vs_WT_F02.11823.11823.2 0.507 16-Jul R.YPMAVGLNK[136.11].G "sp|Q9Y3U8|RL36_HUMAN,tr|J3KTD3|J3KTD3_HUMAN,tr|J3QSB5|J3QSB5_HUMAN" 3 999.5303 1.14 12679 11823 2 999.529461 500.7724 60S ribosomal protein L36 OS=Homo sapiens OX=9606 GN=RPL36 PE=1 SV=3 8.59 2588.1 - 2.75E+06 - - - -0.8274 - 1.323 0.152 - 139.2 1 2 0 -0.0008 9 0 0 0 1.67E+08 1.46E+08 - - - 0.9732 0.9998 221125_WJC_METTL3_EV_vs_WT_F02.11824.11824.2 0.000498 16-Oct R.YLALDEADR[166.11].M sp|Q9UJV9|DDX41_HUMAN 1 1074.5221 0.86 12680 11824 2 1074.521217 538.2683 Probable ATP-dependent RNA helicase DDX41 OS=Homo sapiens OX=9606 GN=DDX41 PE=1 SV=2 4.03 2588.3 - 832707 - - - -0.8301 - 2.044 0.457 - 349 1 2 0 -0.0009 9 0 0 0 9.48E+07 1.10E+08 - - - 4.4844 0.9976 221125_WJC_METTL3_EV_vs_WT_F02.11829.11829.2 0.0347 16-Sep K.WVGDLPNGR.V "sp|Q96DR8|MUCL1_HUMAN,tr|F8VV13|F8VV13_HUMAN,tr|A0A087WWF8|A0A087WWF8_HUMAN" 3 1012.509 7.16 12683 11829 2 1012.507606 507.2618 Mucin-like protein 1 OS=Homo sapiens OX=9606 GN=MUCL1 PE=1 SV=1 5.84 2588.9 - 3.71E+06 - - - -1.4054 - 1.471 0.245 - 292.1 1 2 0 -0.0014 9 0 0 0 5.93E+08 8.28E+07 - - - 1.9667 0.9974 221125_WJC_METTL3_EV_vs_WT_F02.11835.11835.2 0.423 14-Jul K.EAIDSYIK[136.11].A "sp|Q00610|CLH1_HUMAN,tr|A0A087WVQ6|A0A087WVQ6_HUMAN" 2 945.4899 0.92 12686 11835 2 945.488615 473.7522 Clathrin heavy chain 1 OS=Homo sapiens OX=9606 GN=CLTC PE=1 SV=5 4.37 2589.6 - 566483 - - - -1.32 - 1.361 0.253 - 112.9 1 2 0 -0.0012 8 0 0 0 1.35E+07 1.47E+07 - - - 1.8388 0.999 221125_WJC_METTL3_EV_vs_WT_F02.11837.11837.2 0.00404 14-Sep K.ASNIVMLR.M sp|P98175|RBM10_HUMAN 1 902.5008 1.09 12688 11837 2 902.50063 452.2577 RNA-binding protein 10 OS=Homo sapiens OX=9606 GN=RBM10 PE=1 SV=3 9.79 2589.8 - 1.60E+06 - - - -0.1573 - 1.981 0.175 - 356.7 1 2 0 -0.0001 8 0 0 0 5.74E+07 5.28E+07 - - - 2.3952 0.9978 221125_WJC_METTL3_EV_vs_WT_F02.11838.11838.2 0.246 20-Sep R.VVLLGAPNAGK.S "sp|O75616|ERAL1_HUMAN,tr|J3QSB2|J3QSB2_HUMAN,tr|J3QRV9|J3QRV9_HUMAN,tr|J3QT61|J3QT61_HUMAN" 4 1037.6233 12.02 12689 11838 2 1037.623446 519.8189 "GTPase Era, mitochondrial OS=Homo sapiens OX=9606 GN=ERAL1 PE=1 SV=2" 8.72 2589.8 - 724020 - - - 0.1118 - 1.534 0.207 - 174.3 1 2 0 0.0001 11 0 0 0 6.84E+08 5.69E+07 - - - 1.7274 0.9998 221125_WJC_METTL3_EV_vs_WT_F02.11842.11842.2 3.77E-05 20-Oct K.LSAMMGAVAEK[136.11].K "sp|Q86U44|MTA70_HUMAN,tr|F5H6D8|F5H6D8_HUMAN,tr|H0YFV6|H0YFV6_HUMAN,tr|B4DTN4|B4DTN4_HUMAN" 4 1114.5606 0.02 12691 11842 2 1114.560383 558.2876 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 6 2590.4 - 3.39E+07 - - - -0.1965 - 2.181 0.389 - 310.2 1 2 0 -0.0002 11 0 0 0 5.76E+07 2.72E+09 - - - 4.0236 0.9954 221125_WJC_METTL3_EV_vs_WT_F02.11843.11843.2 4.84 12-Jun R.VTVPLVR[166.11].R "sp|Q9UKM9|RALY_HUMAN,tr|Q5QPM0|Q5QPM0_HUMAN,tr|Q5QPM1|Q5QPM1_HUMAN,tr|Q5QPL9|Q5QPL9_HUMAN" 4 792.5097 1.19 12692 11843 2 792.51 397.2621 RNA-binding protein Raly OS=Homo sapiens OX=9606 GN=RALY PE=1 SV=1 9.72 2590.4 - 4.50E+06 - - - 0.3861 - 1.413 0.163 - 167.2 2 2 0 0.0003 7 0 0 0 2.39E+08 2.02E+08 - - - 1.2058 0.9498 221125_WJC_METTL3_EV_vs_WT_F02.11847.11847.2 1.98 12-Jun K.LPYSTFR.T "sp|Q13207|TBX2_HUMAN,sp|O15119|TBX3_HUMAN" 2 882.46 1.07 12694 11847 2 882.459246 442.2373 T-box transcription factor TBX2 OS=Homo sapiens OX=9606 GN=TBX2 PE=1 SV=3 8.75 2590.9 - 2.36E+06 - - - -0.8012 - 1.073 0.049 - 147 1 2 0 -0.0007 7 0 0 0 2.99E+08 2.79E+08 - - - -0.3741 0.9878 221125_WJC_METTL3_EV_vs_WT_F02.11848.11848.2 0.113 18-Oct N.PEAALSPTFR[166.11].S "sp|Q86U44|MTA70_HUMAN,tr|B4E349|B4E349_HUMAN,tr|F5H6D8|F5H6D8_HUMAN,tr|B4DTN4|B4DTN4_HUMAN" 4 1097.5745 0.03 12695 11848 2 1097.573982 549.7945 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 6.43 2591 - 1.17E+06 - - - -0.4528 - 2.116 0.398 - 488.9 1 1 0 -0.0005 10 0 0 0 1.14E+08 3.69E+09 - - - 4.0726 0.9981 221125_WJC_METTL3_EV_vs_WT_F02.11849.11849.2 0.0641 14-Aug R.FGITGYGK.G "sp|Q8NDD1|CA131_HUMAN,tr|Q5TBI2|Q5TBI2_HUMAN,tr|Q5TBH9|Q5TBH9_HUMAN" 3 841.4334 1.59 12696 11849 2 841.432544 421.724 Uncharacterized protein C1orf131 OS=Homo sapiens OX=9606 GN=C1orf131 PE=1 SV=4 8.59 2591 - 1.71E+06 - - - -1.0221 - 1.373 0.268 - 122.7 1 2 0 -0.0009 8 0 0 0 7.85E+07 4.95E+07 - - - 1.9762 0.999 221125_WJC_METTL3_EV_vs_WT_F02.11852.11852.2 0.00341 20-Nov R.VVLLGAPNAGK[136.11].S "sp|O75616|ERAL1_HUMAN,tr|J3QSB2|J3QSB2_HUMAN,tr|J3QRV9|J3QRV9_HUMAN,tr|J3QT61|J3QT61_HUMAN" 4 1045.6375 6.59 12697 11852 2 1045.640878 523.826 "GTPase Era, mitochondrial OS=Homo sapiens OX=9606 GN=ERAL1 PE=1 SV=2" 8.72 2591.4 - 1.33E+06 - - - 3.2019 - 1.979 0.444 - 320 1 2 0 0.0033 11 0 0 0 3.75E+08 5.69E+07 - - - 4.1659 0.9937 221125_WJC_METTL3_EV_vs_WT_F02.11858.11858.2 0.272 16-Aug K.TYAIC[160.03]GAIR.R "sp|P63220|RS21_HUMAN,tr|Q9BYK1|Q9BYK1_HUMAN,tr|Q8WVC2|Q8WVC2_HUMAN" 3 1023.5172 0.52 12700 11858 2 1023.517302 512.7659 40S ribosomal protein S21 OS=Homo sapiens OX=9606 GN=RPS21 PE=1 SV=1 7.89 2592.2 - 3.16E+06 - - - 0.1475 - 1.291 0.158 - 209.4 1 2 0 0.0002 9 0 0 0 1.23E+08 2.37E+08 - - - 0.9469 0.9996 221125_WJC_METTL3_EV_vs_WT_F02.11859.11859.2 0.00737 16-Sep R.YLALDEADR.M sp|Q9UJV9|DDX41_HUMAN 1 1064.5138 0.87 12701 11859 2 1064.513659 533.2642 Probable ATP-dependent RNA helicase DDX41 OS=Homo sapiens OX=9606 GN=DDX41 PE=1 SV=2 4.03 2592.2 - 2.96E+06 - - - -0.1691 - 1.718 0.343 - 280.9 1 2 0 -0.0002 9 0 0 0 9.48E+07 1.10E+08 - - - 3.1399 0.9991 221125_WJC_METTL3_EV_vs_WT_F02.11860.11860.2 0.474 14-Sep R.IATGSFLK.R "sp|P22234|PUR6_HUMAN,tr|D6RF62|D6RF62_HUMAN,tr|E9PBS1|E9PBS1_HUMAN" 3 835.4804 0.76 12702 11860 2 835.480088 418.7475 Multifunctional protein ADE2 OS=Homo sapiens OX=9606 GN=PAICS PE=1 SV=3 8.75 2592.3 - 1.30E+06 - - - -0.3184 - 1.688 0.244 - 160.9 1 2 0 -0.0003 8 0 0 0 1.74E+08 2.29E+08 - - - 2.4221 0.9997 221125_WJC_METTL3_EV_vs_WT_F02.11870.11870.2 0.0477 14/20 K.IGGIGTVPVGR[166.11].V "sp|Q05639|EF1A2_HUMAN,sp|P68104|EF1A1_HUMAN,sp|Q5VTE0|EF1A3_HUMAN,tr|A0A7I2V659|A0A7I2V659_HUMAN,tr|A0A7I2V3H3|A0A7I2V3H3_HUMAN,tr|A0A2U3TZH3|A0A2U3TZH3_HUMAN,tr|A0A7I2V5N4|A0A7I2V5N4_HUMAN,tr|A0A087WVQ9|A0A087WVQ9_HUMAN" 8 1034.6112 0.37 12706 11870 2 1034.610576 518.3129 Elongation factor 1-alpha 2 OS=Homo sapiens OX=9606 GN=EEF1A2 PE=1 SV=1 9.75 2593.6 - 9.65E+06 - - - -0.6022 - 1.992 0.381 - 720.9 1 2 0 -0.0006 11 0 0 0 6.60E+09 1.77E+10 - - - 3.7192 0.8658 221125_WJC_METTL3_EV_vs_WT_F02.11872.11872.2 0.143 14-Jul S.FTPTSVIR.K "sp|Q9NRA8|4ET_HUMAN,tr|B1AKL4|B1AKL4_HUMAN" 2 919.5127 0.66 12707 11872 2 919.512622 460.7636 Eukaryotic translation initiation factor 4E transporter OS=Homo sapiens OX=9606 GN=EIF4ENIF1 PE=1 SV=2 9.75 2593.8 - 1.23E+06 - - - -0.1033 - 1.274 0.246 - 165.8 1 1 0 -0.0001 8 0 0 0 7.04E+07 1.07E+08 - - - 1.5883 0.9997 221125_WJC_METTL3_EV_vs_WT_F02.11877.11877.2 0.00157 20-Oct K.IGGIGTVPVGR.V "sp|Q05639|EF1A2_HUMAN,sp|P68104|EF1A1_HUMAN,sp|Q5VTE0|EF1A3_HUMAN,tr|A0A7I2V659|A0A7I2V659_HUMAN,tr|A0A7I2V3H3|A0A7I2V3H3_HUMAN,tr|A0A2U3TZH3|A0A2U3TZH3_HUMAN,tr|A0A7I2V5N4|A0A7I2V5N4_HUMAN,tr|A0A087WVQ9|A0A087WVQ9_HUMAN" 8 1024.6029 0.37 12710 11877 2 1024.602115 513.3087 Elongation factor 1-alpha 2 OS=Homo sapiens OX=9606 GN=EEF1A2 PE=1 SV=1 9.75 2594.4 - 4.36E+06 - - - -0.7945 - 1.847 0.421 - 303.3 1 2 0 -0.0008 11 0 0 0 6.60E+09 1.77E+10 - - - 3.8101 0.9965 221125_WJC_METTL3_EV_vs_WT_F02.11885.11885.2 0.339 14-Aug K.SIIQEVAR.D sp|Q96JJ7|TMX3_HUMAN 1 914.5185 0.99 12716 11885 2 914.517812 458.2665 Protein disulfide-isomerase TMX3 OS=Homo sapiens OX=9606 GN=TMX3 PE=1 SV=2 5.72 2595.3 - 829095 - - - -0.7862 - 1.556 0.145 - 167.8 1 2 0 -0.0007 8 0 0 0 9.48E+07 9.55E+07 - - - 1.4452 0.9988 221125_WJC_METTL3_EV_vs_WT_F02.11889.11889.2 0.00344 16-Sep R.VPLDEALQR[166.11].G "sp|Q15149|PLEC_HUMAN,tr|H0YDN1|H0YDN1_HUMAN" 2 1049.5745 0.58 12718 11889 2 1049.571827 525.7945 Plectin OS=Homo sapiens OX=9606 GN=PLEC PE=1 SV=3 4.37 2595.7 - 1.12E+06 - - - -2.5267 - 1.932 0.318 - 302.7 1 2 0 -0.0027 9 0 0 0 2.31E+07 3.99E+07 - - - 3.2942 0.9813 221125_WJC_METTL3_EV_vs_WT_F02.11891.11891.2 0.163 14-Jun K.GLVEDTLR[166.11].Q sp|Q15149|PLEC_HUMAN 1 911.4952 1.93 12719 11891 2 911.496225 456.7549 Plectin OS=Homo sapiens OX=9606 GN=PLEC PE=1 SV=3 4.37 2596 - 799713 - - - 1.1618 - 1.48 0.047 - 90.8 2 2 0 0.0011 8 0 0 0 1.11E+08 5.74E+07 - - - 0.4357 0.9986 221125_WJC_METTL3_EV_vs_WT_F02.11902.11902.2 0.267 14-Aug K.GLVEDTLR.Q sp|Q15149|PLEC_HUMAN 1 901.4869 1.94 12723 11902 2 901.486444 451.7507 Plectin OS=Homo sapiens OX=9606 GN=PLEC PE=1 SV=3 4.37 2597.3 - 1.43E+06 - - - -0.5014 - 1.774 0.183 - 195.7 1 2 0 -0.0005 8 0 0 0 1.17E+08 6.06E+07 - - - 2.1214 0.9997 221125_WJC_METTL3_EV_vs_WT_F02.11907.11907.2 0.00027 14-Oct K.VGDC[160.03]VFIK.S "sp|Q86U86|PB1_HUMAN,tr|E7EVG2|E7EVG2_HUMAN" 2 936.4739 1.6 12726 11907 2 936.472966 469.2442 Protein polybromo-1 OS=Homo sapiens OX=9606 GN=PBRM1 PE=1 SV=1 5.8 2597.9 - 1.31E+06 - - - -0.9856 - 1.632 0.437 - 248 1 2 0 -0.0009 8 0 0 0 1.17E+08 7.32E+07 - - - 3.7456 0.9562 221125_WJC_METTL3_EV_vs_WT_F02.11908.11908.2 0.982 16-Jul R.QVLDEALLR.R sp|Q6P087|RUSD3_HUMAN 1 1055.5975 323.44 12727 11908 2 1055.600513 528.806 Mitochondrial mRNA pseudouridine synthase RPUSD3 OS=Homo sapiens OX=9606 GN=RPUSD3 PE=1 SV=3 4.37 2598 - 1.19E+06 - - - 2.8458 - 1.363 0.102 - 178.6 2 2 0 0.003 9 0 0 0 4.61E+07 1.43E+05 - - - 0.5549 0.9987 221125_WJC_METTL3_EV_vs_WT_F02.11915.11915.2 0.0213 16-Sep R.LIVENLSSR[166.11].V "sp|Q13243|SRSF5_HUMAN,sp|Q08170|SRSF4_HUMAN,sp|Q13247|SRSF6_HUMAN,tr|A0A590UK80|A0A590UK80_HUMAN,tr|A0A590UJK4|A0A590UJK4_HUMAN,tr|B4DJK0|B4DJK0_HUMAN,tr|A0A590UJP7|A0A590UJP7_HUMAN,tr|B4DUA4|B4DUA4_HUMAN,tr|A0A0D9SEM4|A0A0D9SEM4_HUMAN,tr|A0A590UK01|A0A590UK01_HUMAN" 10 1039.5901 1.35 12731 11915 2 1039.59177 520.8023 Serine\arginine-rich splicing factor 5 OS=Homo sapiens OX=9606 GN=SRSF5 PE=1 SV=1 6 2598.8 - 8.31E+06 - - - 1.5785 - 1.557 0.319 - 223.2 1 2 0 0.0016 9 0 0 0 7.15E+08 5.28E+08 - - - 2.6775 0.9957 221125_WJC_METTL3_EV_vs_WT_F02.11916.11916.2 0.153 12-Jul K.FMTDPIR.L "sp|P38919|IF4A3_HUMAN,tr|I3L3H2|I3L3H2_HUMAN" 2 878.432 1.33 12732 11916 2 878.43169 440.2233 Eukaryotic initiation factor 4A-III OS=Homo sapiens OX=9606 GN=EIF4A3 PE=1 SV=4 5.84 2598.8 - 4.03E+06 - - - -0.3802 - 1.25 0.198 - 231.7 1 2 0 -0.0003 7 0 0 0 2.33E+08 1.75E+08 - - - 1.2104 0.9994 221125_WJC_METTL3_EV_vs_WT_F02.11917.11917.2 5.76E-06 18-Sep K.LLNENSYVPR[166.11].E "sp|P02786|TFR1_HUMAN,tr|G3V0E5|G3V0E5_HUMAN" 2 1213.6331 1.5 12733 11917 2 1213.6289 607.8238 Transferrin receptor protein 1 OS=Homo sapiens OX=9606 GN=TFRC PE=1 SV=2 6 2599 - 487782 - - - -3.4253 - 1.936 0.574 - 306.5 1 2 0 -0.0042 10 0 0 0 3.53E+07 2.35E+07 - - - 5.1233 0.9057 221125_WJC_METTL3_EV_vs_WT_F02.11925.11925.2 10.1 14-Jul K.FGPALSVK.V "sp|Q9H361|PABP3_HUMAN,sp|P11940|PABP1_HUMAN,tr|A0A7I2YQE4|A0A7I2YQE4_HUMAN,tr|A0A7I2V649|A0A7I2V649_HUMAN,tr|H0YAR2|H0YAR2_HUMAN,tr|E7ERJ7|E7ERJ7_HUMAN,tr|A0A7I2YQ88|A0A7I2YQ88_HUMAN,tr|H0YBN4|H0YBN4_HUMAN,tr|A0A087WTT1|A0A087WTT1_HUMAN,tr|H0YAP2|H0YAP2_HUMAN,tr|A0A7I2YQ90|A0A7I2YQ90_HUMAN,tr|A0A7I2V4N4|A0A7I2V4N4_HUMAN,tr|E7EQV3|E7EQV3_HUMAN" 13 817.4698 1.35 12738 11925 2 817.469504 409.7422 Polyadenylate-binding protein 3 OS=Homo sapiens OX=9606 GN=PABPC3 PE=1 SV=2 8.75 2599.8 - 1.92E+06 - - - -0.3499 - 1.016 0.026 - 116.1 2 2 0 -0.0003 8 0 0 0 2.59E+09 1.91E+09 - - - -0.8537 0.9998 221125_WJC_METTL3_EV_vs_WT_F02.11929.11929.2 0.000482 18-Oct K.LLNENSYVPR.E "sp|P02786|TFR1_HUMAN,tr|G3V0E5|G3V0E5_HUMAN" 2 1203.6248 1.46 12740 11929 2 1203.624771 602.8197 Transferrin receptor protein 1 OS=Homo sapiens OX=9606 GN=TFRC PE=1 SV=2 6 2600.4 - 1.02E+06 - - - -0.0133 - 1.935 0.426 - 251 1 2 0 0 10 0 0 0 3.57E+07 2.45E+07 - - - 4.03 0.9936 221125_WJC_METTL3_EV_vs_WT_F02.11938.11938.2 0.163 16-Jul R.MVGGVLVER[166.11].T sp|Q9UHV9|PFD2_HUMAN 1 968.5353 0.68 12746 11938 2 968.53607 485.2749 Prefoldin subunit 2 OS=Homo sapiens OX=9606 GN=PFDN2 PE=1 SV=1 5.75 2601.4 - 1.85E+06 - - - 0.8394 - 1.44 0.133 - 159.8 1 2 0 0.0008 9 0 0 0 7.64E+07 1.12E+08 - - - 1.078 0.9978 221125_WJC_METTL3_EV_vs_WT_F02.11942.11942.2 0.661 12-Jun K.DDAMLLK.G "sp|P10809|CH60_HUMAN,tr|A0A7I2V2X6|A0A7I2V2X6_HUMAN,tr|A0A7I2YQK6|A0A7I2YQK6_HUMAN,tr|A0A7I2V599|A0A7I2V599_HUMAN" 4 804.4051 1.25 12749 11942 2 804.404594 403.2098 "60 kDa heat shock protein, mitochondrial OS=Homo sapiens OX=9606 GN=HSPD1 PE=1 SV=2" 4.21 2601.8 - 1.39E+07 - - - -0.6788 - 1.542 0.182 - 247.3 1 2 0 -0.0005 7 0 0 0 8.99E+09 7.21E+09 - - - 1.7573 0.9836 221125_WJC_METTL3_EV_vs_WT_F02.11944.11944.2 0.0397 18-Sep N.PEAALSPTFR.S "sp|Q86U44|MTA70_HUMAN,tr|B4E349|B4E349_HUMAN,tr|F5H6D8|F5H6D8_HUMAN,tr|B4DTN4|B4DTN4_HUMAN" 4 1087.5662 0.03 12750 11944 2 1087.566226 544.7904 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 6.43 2602 - 2.05E+06 - - - 0.0156 - 2.101 0.346 - 352.5 1 1 0 0 10 0 0 0 1.15E+08 3.69E+09 - - - 3.6689 0.9994 221125_WJC_METTL3_EV_vs_WT_F02.11947.11947.2 3.59E-07 18-Oct R.SMMMSYAAER.S sp|P18583|SON_HUMAN 1 1175.4773 1.14 12751 11947 2 1175.473087 588.7459 Protein SON OS=Homo sapiens OX=9606 GN=SON PE=1 SV=4 5.72 2602.4 - 718601 - - - -3.6147 - 2.01 0.612 - 417.7 1 2 0 -0.0042 10 0 0 0 3.35E+07 2.95E+07 - - - 5.5086 0.9968 221125_WJC_METTL3_EV_vs_WT_F02.11954.11954.2 3.13 14-Jul K.IVVNLTGR[166.11].L "sp|P62244|RS15A_HUMAN,tr|I3L246|I3L246_HUMAN,tr|I3L3P7|I3L3P7_HUMAN,tr|H3BN98|H3BN98_HUMAN" 4 880.537 0.84 12754 11954 2 880.535803 441.2758 40S ribosomal protein S15a OS=Homo sapiens OX=9606 GN=RPS15A PE=1 SV=2 9.75 2603.2 - 9.00E+06 - - - -1.3265 - 1.458 0.205 - 174.2 1 2 0 -0.0012 8 0 0 0 1.20E+09 1.43E+09 - - - 1.692 0.9882 221125_WJC_METTL3_EV_vs_WT_F02.11955.11955.2 1.18 12-May K.AIDMFNK.A sp|O94826|TOM70_HUMAN 1 837.4055 1.25 12755 11955 2 837.404945 419.71 Mitochondrial import receptor subunit TOM70 OS=Homo sapiens OX=9606 GN=TOMM70 PE=1 SV=1 5.88 2603.3 - 1.40E+06 - - - -0.6329 - 0.919 0.24 - 59.5 1 2 0 -0.0005 7 0 0 0 5.11E+07 4.08E+07 - - - 0.5458 0.9611 221125_WJC_METTL3_EV_vs_WT_F02.11956.11956.2 0.0085 12-Jun K.AIDMFNK[136.11].A sp|O94826|TOM70_HUMAN 1 845.4197 1.26 12756 11956 2 845.415104 423.7171 Mitochondrial import receptor subunit TOM70 OS=Homo sapiens OX=9606 GN=TOMM70 PE=1 SV=1 5.88 2603.4 - 933122 - - - -5.4068 - 1.205 0.319 - 97.5 1 2 0 -0.0046 7 0 0 0 5.11E+07 4.05E+07 - - - 1.9866 0.9999 221125_WJC_METTL3_EV_vs_WT_F02.11961.11961.2 0.000446 18-Sep R.SMMMSYAAER[166.11].S sp|P18583|SON_HUMAN 1 1185.4856 1.14 12758 11961 2 1185.485009 593.7501 Protein SON OS=Homo sapiens OX=9606 GN=SON PE=1 SV=4 5.72 2604 - 1.26E+06 - - - -0.5036 - 1.9 0.551 - 320.3 1 2 0 -0.0006 10 0 0 0 3.35E+07 2.95E+07 - - - 4.9021 0.984 221125_WJC_METTL3_EV_vs_WT_F02.11967.11967.2 0.664 16-Jun K.IISAAFEER[166.11].H "sp|Q96AX1|VP33A_HUMAN,tr|A0A2R8YF87|A0A2R8YF87_HUMAN,tr|H3BMM5|H3BMM5_HUMAN,tr|F5H2X5|F5H2X5_HUMAN" 4 1044.5479 0.3 12762 11967 2 1044.546307 523.2812 Vacuolar protein sorting-associated protein 33A OS=Homo sapiens OX=9606 GN=VPS33A PE=1 SV=1 4.53 2604.6 - 1.91E+06 - - - -1.5538 - 1.307 0.145 - 62.6 4 2 0 -0.0016 9 0 0 0 1.30E+07 4.36E+07 - - - 0.6171 0.9993 221125_WJC_METTL3_EV_vs_WT_F02.11969.11969.2 0.00744 16-Oct K.ILLGGYQSR.A sp|Q99459|CDC5L_HUMAN 1 1005.5607 1.59 12764 11969 2 1005.561177 503.7876 Cell division cycle 5-like protein OS=Homo sapiens OX=9606 GN=CDC5L PE=1 SV=2 8.75 2604.8 - 2.44E+06 - - - 0.4445 - 1.891 0.248 - 271.3 1 2 0 0.0004 9 0 0 0 3.54E+08 2.22E+08 - - - 2.7158 0.9071 221125_WJC_METTL3_EV_vs_WT_F02.11972.11972.2 2.84 16-Jun R.VQEIVGALR.K "sp|Q969T7|5NT3B_HUMAN,tr|E5RJR6|E5RJR6_HUMAN,tr|C9J758|C9J758_HUMAN" 3 983.5764 2.57 12765 11972 2 983.578813 492.7955 7-methylguanosine phosphate-specific 5'-nucleotidase OS=Homo sapiens OX=9606 GN=NT5C3B PE=1 SV=4 5.97 2605.2 - 955920 - - - 2.4736 - 1.392 0.057 - 73.6 17 2 0 0.0024 9 0 0 0 4.96E+07 1.93E+07 - - - -0.1316 0.9991 221125_WJC_METTL3_EV_vs_WT_F02.11978.11978.2 0.00205 16-Sep R.LEETQALLR[166.11].K "sp|Q14203|DCTN1_HUMAN,tr|A0A804CDA6|A0A804CDA6_HUMAN,tr|E7EX90|E7EX90_HUMAN,tr|A0A7P0Z4C3|A0A7P0Z4C3_HUMAN" 4 1081.6007 1.81 12769 11978 2 1081.597963 541.8076 Dynactin subunit 1 OS=Homo sapiens OX=9606 GN=DCTN1 PE=1 SV=3 4.53 2605.8 - 2.13E+06 - - - -2.525 - 2.11 0.337 - 250.5 1 2 0 -0.0027 9 0 0 0 9.40E+08 5.20E+08 - - - 3.6894 0.9996 221125_WJC_METTL3_EV_vs_WT_F02.11981.11981.2 0.00518 16-Aug K.LFEAVEEGR.S sp|O43395|PRPF3_HUMAN 1 1048.5189 2.19 12771 11981 2 1048.518392 525.2667 U4\U6 small nuclear ribonucleoprotein Prp3 OS=Homo sapiens OX=9606 GN=PRPF3 PE=1 SV=2 4.25 2606.1 - 916385 - - - -0.5083 - 1.696 0.363 - 187.8 1 2 0 -0.0005 9 0 0 0 8.28E+08 3.79E+08 - - - 3.2503 0.9863 221125_WJC_METTL3_EV_vs_WT_F02.11982.11982.2 1.59 16-Jun K.ILLGGYQSR[166.11].A sp|Q99459|CDC5L_HUMAN 1 1015.569 1.59 12772 11982 2 1015.570423 508.7918 Cell division cycle 5-like protein OS=Homo sapiens OX=9606 GN=CDC5L PE=1 SV=2 8.75 2606.2 - 5.21E+06 - - - 1.4012 - 1.252 0.159 - 75.6 2 2 0 0.0014 9 0 0 0 3.56E+08 2.23E+08 - - - 0.7306 0.9888 221125_WJC_METTL3_EV_vs_WT_F02.11983.11983.2 0.457 20-Aug R.LLALSGPGGGR.G "sp|Q9H307|PININ_HUMAN,tr|G3V5F0|G3V5F0_HUMAN,tr|G3V579|G3V579_HUMAN" 3 996.5716 1.2 12773 11983 2 996.568358 499.2931 Pinin OS=Homo sapiens OX=9606 GN=PNN PE=1 SV=5 9.75 2606.2 - 2.61E+06 - - - -3.2823 - 1.742 0.166 - 183.6 1 2 0 -0.0033 11 0 0 0 3.51E+08 2.92E+08 - - - 1.7675 0.9957 221125_WJC_METTL3_EV_vs_WT_F02.11985.11985.2 0.408 14-Jul K.ALDPEIYR.N sp|Q9NP73|ALG13_HUMAN 1 975.5025 3.58 12775 11985 2 975.499935 488.7585 Putative bifunctional UDP-N-acetylglucosamine transferase and deubiquitinase ALG13 OS=Homo sapiens OX=9606 GN=ALG13 PE=1 SV=2 4.37 2606.4 - 933006 - - - -2.6766 - 1.629 0.227 - 159.8 1 2 0 -0.0026 8 0 0 0 3.67E+07 1.03E+07 - - - 2.1885 0.976 221125_WJC_METTL3_EV_vs_WT_F02.11986.11986.2 2.32 14-Jun R.GLGGIMVK.R sp|O94776|MTA2_HUMAN 1 773.4469 0.88 12776 11986 2 773.446402 387.7307 Metastasis-associated protein MTA2 OS=Homo sapiens OX=9606 GN=MTA2 PE=1 SV=1 8.75 2606.5 - 851742 - - - -0.7033 - 0.994 0.162 - 84.7 2 2 0 -0.0005 8 0 0 0 1.89E+07 2.16E+07 - - - 0.0847 0.9996 221125_WJC_METTL3_EV_vs_WT_F02.11989.11989.2 0.0104 12-Jul K.MMEIMTR[166.11].E "sp|P61247|RS3A_HUMAN,tr|H0Y8L7|H0Y8L7_HUMAN,tr|D6R9B6|D6R9B6_HUMAN,tr|H0Y9Y4|H0Y9Y4_HUMAN,tr|D6RB09|D6RB09_HUMAN,tr|E9PFI5|E9PFI5_HUMAN,tr|D6RAT0|D6RAT0_HUMAN,tr|D6RG13|D6RG13_HUMAN" 8 920.4157 0.81 12777 11989 2 920.414692 461.2151 40S ribosomal protein S3a OS=Homo sapiens OX=9606 GN=RPS3A PE=1 SV=2 5.75 2606.9 - 4.83E+06 - - - -1.1332 - 1.697 0.392 - 256.9 1 2 0 -0.001 7 0 0 0 1.56E+08 1.93E+08 - - - 3.6117 0.9993 221125_WJC_METTL3_EV_vs_WT_F02.11991.11991.2 0.0266 12-Jul R.TYMDVMR.E sp|O75533|SF3B1_HUMAN 1 914.399 1.24 12779 11991 2 914.398942 458.2068 Splicing factor 3B subunit 1 OS=Homo sapiens OX=9606 GN=SF3B1 PE=1 SV=3 5.5 2607 - 2.73E+06 - - - -0.0733 - 1.18 0.43 - 205.3 1 2 0 -0.0001 7 0 0 0 6.42E+07 5.18E+07 - - - 2.7414 0.9956 221125_WJC_METTL3_EV_vs_WT_F02.11992.11992.2 0.185 14-Jul K.ALSVGLVK.G "sp|Q9UNM6|PSD13_HUMAN,tr|J3KNQ3|J3KNQ3_HUMAN,tr|A0A087WUL9|A0A087WUL9_HUMAN" 3 785.5011 0.56 12780 11992 2 785.500201 393.7578 26S proteasome non-ATPase regulatory subunit 13 OS=Homo sapiens OX=9606 GN=PSMD13 PE=1 SV=2 8.8 2607.1 - 2.37E+06 - - - -1.1318 - 1.386 0.182 - 144 1 2 0 -0.0009 8 0 0 0 4.70E+07 8.39E+07 - - - 1.3694 0.9991 221125_WJC_METTL3_EV_vs_WT_F02.11998.11998.2 0.00242 12-Aug K.MMEIMTR.E "sp|P61247|RS3A_HUMAN,tr|H0Y8L7|H0Y8L7_HUMAN,tr|D6R9B6|D6R9B6_HUMAN,tr|H0Y9Y4|H0Y9Y4_HUMAN,tr|D6RB09|D6RB09_HUMAN,tr|E9PFI5|E9PFI5_HUMAN,tr|D6RAT0|D6RAT0_HUMAN,tr|D6RG13|D6RG13_HUMAN" 8 910.4075 0.81 12784 11998 2 910.405036 456.211 40S ribosomal protein S3a OS=Homo sapiens OX=9606 GN=RPS3A PE=1 SV=2 5.75 2607.8 - 3.70E+06 - - - -2.668 - 1.506 0.462 - 313.2 1 2 0 -0.0024 7 0 0 0 1.56E+08 1.93E+08 - - - 3.75 0.9996 221125_WJC_METTL3_EV_vs_WT_F02.12001.12001.2 0.000376 18-Dec K.MADEAILQER.E sp|Q9HCD5|NCOA5_HUMAN 1 1174.5652 3.95 12787 12001 2 1174.568235 588.2899 Nuclear receptor coactivator 5 OS=Homo sapiens OX=9606 GN=NCOA5 PE=1 SV=2 4.14 2608.1 - 713086 - - - 2.5644 - 2.41 0.44 - 686.5 1 2 0 0.003 10 0 0 0 1.80E+07 4.55E+06 - - - 4.7452 0.9896 221125_WJC_METTL3_EV_vs_WT_F02.12005.12005.2 0.987 12-Jun R.EFVMQVK[136.11].V "sp|Q9NUL3|STAU2_HUMAN,sp|O95793|STAU1_HUMAN,tr|E5RJN7|E5RJN7_HUMAN,tr|Q5JW30|Q5JW30_HUMAN,tr|E7EVJ4|E7EVJ4_HUMAN,tr|E7EVI1|E7EVI1_HUMAN,tr|E7EPX0|E7EPX0_HUMAN" 7 887.4666 1.72 12789 12005 2 887.465383 444.7406 Double-stranded RNA-binding protein Staufen homolog 2 OS=Homo sapiens OX=9606 GN=STAU2 PE=1 SV=2 6.1 2608.6 - 2.77E+06 - - - -1.3995 - 1.261 0.146 - 154.9 1 2 0 -0.0012 7 0 0 0 3.74E+08 2.17E+08 - - - 0.8538 0.9979 221125_WJC_METTL3_EV_vs_WT_F02.12014.12014.2 0.061 12-Jun K.LDIEQYR.M "sp|P43304|GPDM_HUMAN,tr|F5GYK7|F5GYK7_HUMAN" 2 935.4712 0.97 12796 12014 2 935.470028 468.7429 "Glycerol-3-phosphate dehydrogenase, mitochondrial OS=Homo sapiens OX=9606 GN=GPD2 PE=1 SV=3" 4.37 2609.6 - 856780 - - - -1.302 - 1.504 0.229 - 96.8 1 2 0 -0.0012 7 0 0 0 3.97E+07 4.08E+07 - - - 2.0252 0.9939 221125_WJC_METTL3_EV_vs_WT_F02.12019.12019.2 0.928 12-Jul R.MLVELSK[136.11].A sp|P50991|TCPD_HUMAN 1 826.4714 0.1 12799 12019 2 826.470115 414.243 T-complex protein 1 subunit delta OS=Homo sapiens OX=9606 GN=CCT4 PE=1 SV=4 5.75 2610.2 - 3.25E+07 - - - -1.5258 - 1.44 0.147 - 183.9 1 2 0 -0.0013 7 0 0 0 2.54E+08 2.44E+09 - - - 1.2817 0.9992 221125_WJC_METTL3_EV_vs_WT_F02.12021.12021.2 0.181 12-Aug R.IVYLYTK.K sp|P49207|RL34_HUMAN 1 898.5164 0.88 12801 12021 2 898.5151 450.2655 60S ribosomal protein L34 OS=Homo sapiens OX=9606 GN=RPL34 PE=1 SV=3 8.5 2610.4 - 1.51E+06 - - - -1.4524 - 1.534 0.342 - 193.9 1 2 0 -0.0013 7 0 0 0 8.08E+07 9.18E+07 - - - 2.9224 0.9949 221125_WJC_METTL3_EV_vs_WT_F02.12024.12024.2 0.775 14-Jul K.VLEC[160.03]DIIK.N "sp|Q9BWF3|RBM4_HUMAN,sp|Q9BQ04|RBM4B_HUMAN,tr|E9PM61|E9PM61_HUMAN,tr|D6R9K7|D6R9K7_HUMAN,tr|J3QRR5|J3QRR5_HUMAN,tr|E9PB51|E9PB51_HUMAN,tr|U3KQD5|U3KQD5_HUMAN,tr|E9PLB0|E9PLB0_HUMAN" 8 988.5263 1.44 12802 12024 2 988.525437 495.2704 RNA-binding protein 4 OS=Homo sapiens OX=9606 GN=RBM4 PE=1 SV=1 4.37 2610.9 - 2.52E+06 - - - -0.8912 - 1.201 0.215 - 129.7 1 2 0 -0.0009 8 0 0 0 1.79E+09 1.24E+09 - - - 1.1811 0.9995 221125_WJC_METTL3_EV_vs_WT_F02.12029.12029.2 0.00838 12-Jul R.TGQLFLK.L sp|Q6P2Q9|PRP8_HUMAN 1 805.4698 1.51 12804 12029 2 805.469562 403.7422 Pre-mRNA-processing-splicing factor 8 OS=Homo sapiens OX=9606 GN=PRPF8 PE=1 SV=2 8.41 2611.5 - 2.16E+06 - - - -0.2831 - 1.659 0.324 - 187.8 1 2 0 -0.0002 7 0 0 0 7.85E+07 5.20E+07 - - - 3.038 0.7969 221125_WJC_METTL3_EV_vs_WT_F02.12031.12031.2 0.0118 12-Jul H.TFYNELR.V "sp|Q6S8J3|POTEE_HUMAN,sp|P63261|ACTG_HUMAN,sp|P68133|ACTS_HUMAN,sp|Q9BYX7|ACTBM_HUMAN,sp|P68032|ACTC_HUMAN,sp|Q562R1|ACTBL_HUMAN,sp|P60709|ACTB_HUMAN,sp|A5A3E0|POTEF_HUMAN,sp|P0CG38|POTEI_HUMAN,sp|P0CG39|POTEJ_HUMAN,tr|A0A804GS07|A0A804GS07_HUMAN,tr|I3L3I0|I3L3I0_HUMAN,tr|G5E9R0|G5E9R0_HUMAN,tr|E7EVS6|E7EVS6_HUMAN,tr|A0A6Q8PFE4|A0A6Q8PFE4_HUMAN,tr|J3KT65|J3KT65_HUMAN,tr|I3L3R2|I3L3R2_HUMAN,tr|K7EM38|K7EM38_HUMAN,tr|A0A6Q8PH58|A0A6Q8PH58_HUMAN,tr|I3L1U9|I3L1U9_HUMAN,tr|A0A804HKV3|A0A804HKV3_HUMAN,tr|A0A2R8Y793|A0A2R8Y793_HUMAN,tr|I3L4N8|I3L4N8_HUMAN,tr|C9JUM1|C9JUM1_HUMAN,tr|C9JZR7|C9JZR7_HUMAN,tr|A0A2R8YGF8|A0A2R8YGF8_HUMAN,tr|A6NL76|A6NL76_HUMAN" 27 941.4607 0.7 12806 12031 2 941.45986 471.7376 POTE ankyrin domain family member E OS=Homo sapiens OX=9606 GN=POTEE PE=2 SV=3 5.66 2611.8 - 589322 - - - -0.872 - 1.104 0.266 - 222 1 1 0 -0.0008 7 0 0 0 1.76E+07 2.50E+07 - - - 1.3189 0.9992 221125_WJC_METTL3_EV_vs_WT_F02.12032.12032.2 0.000104 18-Sep K.TLEDPDLNVR[166.11].R "sp|Q86VP6|CAND1_HUMAN,tr|A0A0C4DGH5|A0A0C4DGH5_HUMAN" 2 1180.5963 0.92 12807 12032 2 1180.593506 591.3054 Cullin-associated NEDD8-dissociated protein 1 OS=Homo sapiens OX=9606 GN=CAND1 PE=1 SV=2 4.03 2611.9 - 377005 - - - -2.3979 - 1.634 0.449 - 210.9 1 2 0 -0.0028 10 0 0 0 1.90E+07 2.07E+07 - - - 3.727 0.9991 221125_WJC_METTL3_EV_vs_WT_F02.12036.12036.2 0.0565 12-Jun K.MMVAGFK[136.11].K "sp|Q00839|HNRPU_HUMAN,tr|A0A1W2PQL0|A0A1W2PQL0_HUMAN,tr|A0A1W2PPL4|A0A1W2PPL4_HUMAN,tr|A0A1W2PQ74|A0A1W2PQ74_HUMAN,tr|Q5RI18|Q5RI18_HUMAN,tr|A0A1W2PP35|A0A1W2PP35_HUMAN,tr|A0A1W2PPS1|A0A1W2PPS1_HUMAN,tr|A0A1W2PRZ7|A0A1W2PRZ7_HUMAN,tr|A0A1W2PPH7|A0A1W2PPH7_HUMAN,tr|A0A1W2PQD4|A0A1W2PQD4_HUMAN,tr|A0A1W2PP34|A0A1W2PP34_HUMAN,tr|A0A1X7SBS1|A0A1X7SBS1_HUMAN" 12 790.3961 0.82 12809 12036 2 790.395988 396.2053 Heterogeneous nuclear ribonucleoprotein U OS=Homo sapiens OX=9606 GN=HNRNPU PE=1 SV=6 8.5 2612.4 - 6.87E+06 - - - -0.1442 - 1.415 0.315 - 104.2 1 2 0 -0.0001 7 0 0 0 1.52E+08 1.86E+08 - - - 2.4675 0.9983 221125_WJC_METTL3_EV_vs_WT_F02.12039.12039.2 0.317 14-Aug K.EVEVTLVR[166.11].K sp|Q96T58|MINT_HUMAN 1 953.5421 1.45 12810 12039 2 953.541733 477.7783 Msx2-interacting protein OS=Homo sapiens OX=9606 GN=SPEN PE=1 SV=1 4.53 2612.8 - 849791 - - - -0.4017 - 1.636 0.192 - 311.9 1 2 0 -0.0004 8 0 0 0 6.77E+07 4.67E+07 - - - 1.9436 0.9994 221125_WJC_METTL3_EV_vs_WT_F02.12041.12041.2 0.000719 18-Sep K.TLEDPDLNVR.R "sp|Q86VP6|CAND1_HUMAN,tr|A0A0C4DGH5|A0A0C4DGH5_HUMAN" 2 1170.5881 0.79 12812 12041 2 1170.591086 586.3013 Cullin-associated NEDD8-dissociated protein 1 OS=Homo sapiens OX=9606 GN=CAND1 PE=1 SV=2 4.03 2613.1 - 414292 - - - 2.579 - 1.664 0.511 - 137.4 1 2 0 0.003 10 0 0 0 1.48E+07 1.88E+07 - - - 4.2357 0.9968 221125_WJC_METTL3_EV_vs_WT_F02.12044.12044.2 1.21 14-Aug K.MEIAELNR.T sp|Q7Z794|K2C1B_HUMAN 1 974.4855 35.72 12813 12044 2 974.486039 488.25 "Keratin, type II cytoskeletal 1b OS=Homo sapiens OX=9606 GN=KRT77 PE=1 SV=3" 4.53 2613.5 - 1.55E+06 - - - 0.5367 - 1.571 0.148 - 271.6 1 2 0 0.0005 8 0 0 0 4.84E+07 1.35E+06 - - - 1.4963 0.998 221125_WJC_METTL3_EV_vs_WT_F02.12051.12051.2 0.0673 14-Sep K.VLEC[160.03]DIIK[136.11].N "sp|Q9BWF3|RBM4_HUMAN,sp|Q9BQ04|RBM4B_HUMAN,tr|E9PM61|E9PM61_HUMAN,tr|D6R9K7|D6R9K7_HUMAN,tr|J3QRR5|J3QRR5_HUMAN,tr|E9PB51|E9PB51_HUMAN,tr|U3KQD5|U3KQD5_HUMAN,tr|E9PLB0|E9PLB0_HUMAN" 8 996.5405 1.47 12818 12051 2 996.540095 499.2775 RNA-binding protein 4 OS=Homo sapiens OX=9606 GN=RBM4 PE=1 SV=1 4.37 2614.3 - 1.64E+07 - - - -0.4245 - 1.456 0.218 - 202.3 1 2 0 -0.0004 8 0 0 0 1.78E+09 1.22E+09 - - - 1.7841 0.9993 221125_WJC_METTL3_EV_vs_WT_F02.12053.12053.2 0.00234 16-Oct R.LLEYDTVTR.E "sp|Q9HDC9|APMAP_HUMAN,tr|H0Y512|H0Y512_HUMAN" 2 1108.5764 1.21 12819 12053 2 1108.578837 555.2955 Adipocyte plasma membrane-associated protein OS=Homo sapiens OX=9606 GN=APMAP PE=1 SV=2 4.37 2614.5 - 3.45E+06 - - - 2.1622 - 1.933 0.374 - 359.3 1 2 0 0.0024 9 0 0 0 1.02E+08 8.49E+07 - - - 3.7093 0.9765 221125_WJC_METTL3_EV_vs_WT_F02.12055.12055.2 0.00568 12-May K.GFDEYMK.E sp|Q01469|FABP5_HUMAN 1 888.3688 75 12821 12055 2 888.368544 445.1917 Fatty acid-binding protein 5 OS=Homo sapiens OX=9606 GN=FABP5 PE=1 SV=3 4.37 2614.7 - 7.42E+06 - - - -0.2375 - 0.997 0.138 - 81.7 1 2 0 -0.0002 7 0 0 0 4.05E+08 5.39E+06 - - - 0.0507 0.9955 221125_WJC_METTL3_EV_vs_WT_F02.12056.12056.2 0.308 12-Aug K.LTLLNPK.G sp|P53396|ACLY_HUMAN 1 797.5011 0.61 12822 12056 2 797.501632 399.7578 ATP-citrate synthase OS=Homo sapiens OX=9606 GN=ACLY PE=1 SV=3 8.75 2614.9 - 1.35E+06 - - - 0.6796 - 1.595 0.121 - 214.2 2 2 0 0.0005 7 0 0 0 6.14E+07 1.00E+08 - - - 1.2794 0.9919 221125_WJC_METTL3_EV_vs_WT_F02.12059.12059.2 0.128 12-Jul R.IWDTLQK[136.11].L "sp|P42704|LPPRC_HUMAN,tr|A0A804HI14|A0A804HI14_HUMAN,tr|A0A804HL40|A0A804HL40_HUMAN,tr|A0A804HKJ0|A0A804HKJ0_HUMAN,tr|A0A804HKR3|A0A804HKR3_HUMAN,tr|A0A0C4DG06|A0A0C4DG06_HUMAN,tr|A0A804HIN4|A0A804HIN4_HUMAN,tr|A0A804HLG8|A0A804HLG8_HUMAN,tr|A0A804HIV5|A0A804HIV5_HUMAN,tr|A0A804HHY9|A0A804HHY9_HUMAN,tr|A0A804HJH8|A0A804HJH8_HUMAN,tr|B8ZZ38|B8ZZ38_HUMAN,tr|A0A804HI40|A0A804HI40_HUMAN,tr|A0A804HJZ1|A0A804HJZ1_HUMAN,tr|C9JCA9|C9JCA9_HUMAN,tr|A0A804HIQ7|A0A804HIQ7_HUMAN,tr|A0A804HK30|A0A804HK30_HUMAN,tr|A0A804HKI2|A0A804HKI2_HUMAN,tr|A0A804HKR5|A0A804HKR5_HUMAN,tr|A0A804HKX0|A0A804HKX0_HUMAN,tr|A0A804HIG4|A0A804HIG4_HUMAN,tr|A0A804HK02|A0A804HK02_HUMAN" 22 910.5004 1.06 12823 12059 2 910.498569 456.2575 "Leucine-rich PPR motif-containing protein, mitochondrial OS=Homo sapiens OX=9606 GN=LRPPRC PE=1 SV=3" 5.84 2615.2 - 3.17E+06 - - - -1.9758 - 1.295 0.194 - 120 1 2 0 -0.0018 7 0 0 0 8.11E+07 7.62E+07 - - - 1.2924 0.998 221125_WJC_METTL3_EV_vs_WT_F02.12060.12060.2 0.157 12-Aug K.LTLLNPK[136.11].G sp|P53396|ACLY_HUMAN 1 805.5153 0.62 12824 12060 2 805.514975 403.7649 ATP-citrate synthase OS=Homo sapiens OX=9606 GN=ACLY PE=1 SV=3 8.75 2615.3 - 2.19E+06 - - - -0.3911 - 1.68 0.15 - 205.9 1 2 0 -0.0003 7 0 0 0 6.24E+07 1.01E+08 - - - 1.7926 0.994 221125_WJC_METTL3_EV_vs_WT_F02.12062.12062.2 0.511 12-Jul R.FAGVDIR.V "sp|P62249|RS16_HUMAN,tr|M0R210|M0R210_HUMAN,tr|M0R3H0|M0R3H0_HUMAN,tr|M0QX76|M0QX76_HUMAN,tr|M0R1M5|M0R1M5_HUMAN,tr|Q6IPX4|Q6IPX4_HUMAN" 6 776.4181 0.81 12826 12062 2 776.41831 389.2163 40S ribosomal protein S16 OS=Homo sapiens OX=9606 GN=RPS16 PE=1 SV=2 5.84 2615.4 - 3.39E+06 - - - 0.2859 - 1.278 0.16 - 143.4 1 2 0 0.0002 7 0 0 0 1.45E+09 1.79E+09 - - - 0.9999 0.9988 221125_WJC_METTL3_EV_vs_WT_F02.12065.12065.2 0.401 12-Jul R.FAGVDIR[166.11].V "sp|P62249|RS16_HUMAN,tr|M0R210|M0R210_HUMAN,tr|M0R3H0|M0R3H0_HUMAN,tr|M0QX76|M0QX76_HUMAN,tr|M0R1M5|M0R1M5_HUMAN,tr|Q6IPX4|Q6IPX4_HUMAN" 6 786.4264 0.81 12827 12065 2 786.425915 394.2205 40S ribosomal protein S16 OS=Homo sapiens OX=9606 GN=RPS16 PE=1 SV=2 5.84 2615.8 - 8.54E+06 - - - -0.5633 - 1.506 0.256 - 156.4 1 2 0 -0.0004 7 0 0 0 1.45E+09 1.79E+09 - - - 2.2291 0.9994 221125_WJC_METTL3_EV_vs_WT_F02.12070.12070.2 0.683 14-Aug R.SDLLLSGR[166.11].D "sp|O14744|ANM5_HUMAN,tr|C9JSX3|C9JSX3_HUMAN,tr|G3V580|G3V580_HUMAN,tr|G3V2L6|G3V2L6_HUMAN,tr|G3V5L5|G3V5L5_HUMAN" 5 869.4846 2.63 12831 12070 2 869.483886 435.7496 Protein arginine N-methyltransferase 5 OS=Homo sapiens OX=9606 GN=PRMT5 PE=1 SV=4 5.55 2616.3 - 3.95E+07 - - - -0.8223 - 1.766 0.301 - 267.5 1 2 0 -0.0007 8 0 0 0 3.14E+09 1.19E+09 - - - 2.9792 0.9985 221125_WJC_METTL3_EV_vs_WT_F02.12071.12071.2 1.5 14-Sep K.EVEVTLVR.K sp|Q96T58|MINT_HUMAN 1 943.5338 1.45 12832 12071 2 943.532978 472.7742 Msx2-interacting protein OS=Homo sapiens OX=9606 GN=SPEN PE=1 SV=1 4.53 2616.3 - 3.19E+06 - - - -0.9199 - 1.7 0.205 - 453.2 1 2 0 -0.0009 8 0 0 0 6.75E+07 4.67E+07 - - - 2.1552 0.9976 221125_WJC_METTL3_EV_vs_WT_F02.12075.12075.2 0.0426 14-Jun K.LLGEQYYK[136.11].D "sp|Q92785|REQU_HUMAN,tr|J3KMZ8|J3KMZ8_HUMAN,tr|E9PN04|E9PN04_HUMAN" 3 1020.5371 1.06 12834 12075 2 1020.536761 511.2758 Zinc finger protein ubi-d4 OS=Homo sapiens OX=9606 GN=DPF2 PE=1 SV=2 6 2616.8 - 8.08E+06 - - - -0.3782 - 1.116 0.31 - 84.8 1 2 0 -0.0004 8 0 0 0 2.23E+08 2.11E+08 - - - 1.6615 0.9982 221125_WJC_METTL3_EV_vs_WT_F02.12077.12077.2 0.0184 14-Aug K.VGDVVEFR.G "sp|Q9UHQ9|NB5R1_HUMAN,tr|H7C0R7|H7C0R7_HUMAN" 2 919.4763 0.91 12836 12077 2 919.475255 460.7454 NADH-cytochrome b5 reductase 1 OS=Homo sapiens OX=9606 GN=CYB5R1 PE=1 SV=1 4.37 2616.9 - 853692 - - - -1.1702 - 1.47 0.258 - 176.7 1 2 0 -0.0011 8 0 0 0 3.36E+07 3.68E+07 - - - 2.1082 0.996 221125_WJC_METTL3_EV_vs_WT_F02.12082.12082.2 0.00355 12-Jul R.VYNWDVK[136.11].R sp|P61758|PFD3_HUMAN 1 930.4691 0.65 12839 12082 2 930.468862 466.2418 Prefoldin subunit 3 OS=Homo sapiens OX=9606 GN=VBP1 PE=1 SV=4 5.81 2617.6 - 2.00E+06 - - - -0.2214 - 1.386 0.161 - 162.3 1 2 0 -0.0002 7 0 0 0 4.77E+07 7.34E+07 - - - 1.2644 0.9995 221125_WJC_METTL3_EV_vs_WT_F02.12087.12087.2 0.0283 12-Jul R.VDFSITK.R "sp|P62995|TRA2B_HUMAN,tr|H7BXF3|H7BXF3_HUMAN,tr|H7C2L4|H7C2L4_HUMAN" 3 808.4331 1.72 12842 12087 2 808.432711 405.2238 Transformer-2 protein homolog beta OS=Homo sapiens OX=9606 GN=TRA2B PE=1 SV=1 5.81 2618 - 2.62E+06 - - - -0.4441 - 1.725 0.313 - 161.1 1 2 0 -0.0004 7 0 0 0 1.36E+08 7.93E+07 - - - 3.0803 0.9996 221125_WJC_METTL3_EV_vs_WT_F02.12088.12088.2 0.0584 18-Oct K.LVLYPSAQEK[136.11].V "sp|Q6L8Q7|PDE12_HUMAN,tr|F6T1Q0|F6T1Q0_HUMAN" 2 1154.6427 0.95 12843 12088 2 1154.643863 578.3286 "2',5'-phosphodiesterase 12 OS=Homo sapiens OX=9606 GN=PDE12 PE=1 SV=2" 6 2618.2 - 980761 - - - 1.0289 - 2.021 0.352 - 369.6 1 2 0 0.0012 10 0 0 0 9.43E+07 9.91E+07 - - - 3.6044 0.998 221125_WJC_METTL3_EV_vs_WT_F02.12089.12089.2 3.11E-05 22-Sep R.MVPAGMGAGLER.M "sp|P52272|HNRPM_HUMAN,tr|M0R2I7|M0R2I7_HUMAN,tr|A0A087X0X3|A0A087X0X3_HUMAN,tr|M0QZM1|M0QZM1_HUMAN" 4 1187.5791 1.38 12844 12089 2 1187.574147 594.7968 Heterogeneous nuclear ribonucleoprotein M OS=Homo sapiens OX=9606 GN=HNRNPM PE=1 SV=3 5.75 2618.3 - 383048 - - - -4.1698 - 1.79 0.485 - 311.3 1 2 0 -0.005 12 0 0 0 5.70E+08 4.14E+08 - - - 4.1536 0.9991 221125_WJC_METTL3_EV_vs_WT_F02.12093.12093.2 0.0202 18-Oct K.IPVGPETLGR.L "sp|P06576|ATPB_HUMAN,tr|F8W079|F8W079_HUMAN,tr|H0YH81|H0YH81_HUMAN" 3 1037.5869 1.82 12846 12093 2 1037.585653 519.8007 "ATP synthase subunit beta, mitochondrial OS=Homo sapiens OX=9606 GN=ATP5F1B PE=1 SV=3" 6 2618.8 - 7.79E+06 - - - -1.2452 - 1.661 0.314 - 354.8 1 2 0 -0.0013 10 0 0 0 1.10E+09 6.02E+08 - - - 2.7762 0.9997 221125_WJC_METTL3_EV_vs_WT_F02.12094.12094.2 0.00426 14-Jul K.YGVTTIVR[166.11].V "sp|Q93096|TP4A1_HUMAN,sp|Q12974|TP4A2_HUMAN,tr|E9PRR9|E9PRR9_HUMAN,tr|E9PMY3|E9PMY3_HUMAN,tr|E9PJC0|E9PJC0_HUMAN,tr|E9PML8|E9PML8_HUMAN,tr|A0A0D9SGK2|A0A0D9SGK2_HUMAN" 7 917.521 2 12847 12094 2 917.520718 459.7678 Protein tyrosine phosphatase type IVA 1 OS=Homo sapiens OX=9606 GN=PTP4A1 PE=1 SV=2 8.75 2618.9 - 1.16E+06 - - - -0.2932 - 1.539 0.455 - 162 1 2 0 -0.0003 8 0 0 0 4.85E+07 2.42E+07 - - - 3.7018 0.9994 221125_WJC_METTL3_EV_vs_WT_F02.12096.12096.2 0.0234 18-Oct K.LVLYPSAQEK.V "sp|Q6L8Q7|PDE12_HUMAN,tr|F6T1Q0|F6T1Q0_HUMAN" 2 1146.6285 0.95 12849 12096 2 1146.629657 574.3215 "2',5'-phosphodiesterase 12 OS=Homo sapiens OX=9606 GN=PDE12 PE=1 SV=2" 6 2619.1 - 1.24E+06 - - - 1.0308 - 1.798 0.333 - 403.8 1 2 0 0.0012 10 0 0 0 9.43E+07 9.91E+07 - - - 3.1378 0.9995 221125_WJC_METTL3_EV_vs_WT_F02.12099.12099.2 0.000989 14-Jul K.LLGEQYYK.D "sp|Q92785|REQU_HUMAN,tr|J3KMZ8|J3KMZ8_HUMAN,tr|E9PN04|E9PN04_HUMAN" 3 1012.5229 1.07 12851 12099 2 1012.522283 507.2687 Zinc finger protein ubi-d4 OS=Homo sapiens OX=9606 GN=DPF2 PE=1 SV=2 6 2619.4 - 6.78E+06 - - - -0.6558 - 1.511 0.377 - 123.8 1 2 0 -0.0007 8 0 0 0 2.23E+08 2.08E+08 - - - 3.0702 0.9992 221125_WJC_METTL3_EV_vs_WT_F02.12104.12104.2 0.00317 14-Jul K.YGVTTIVR.V "sp|Q93096|TP4A1_HUMAN,sp|Q12974|TP4A2_HUMAN,tr|E9PRR9|E9PRR9_HUMAN,tr|E9PMY3|E9PMY3_HUMAN,tr|E9PJC0|E9PJC0_HUMAN,tr|E9PML8|E9PML8_HUMAN,tr|A0A0D9SGK2|A0A0D9SGK2_HUMAN" 7 907.5127 1.75 12855 12104 2 907.51256 454.7636 Protein tyrosine phosphatase type IVA 1 OS=Homo sapiens OX=9606 GN=PTP4A1 PE=1 SV=2 8.75 2619.8 - 934175 - - - -0.173 - 1.459 0.327 - 137 1 2 0 -0.0002 8 0 0 0 4.23E+07 2.41E+07 - - - 2.5955 0.9999 221125_WJC_METTL3_EV_vs_WT_F02.12110.12110.2 2.70E-05 20-Nov K.LSAMMGAVAEK[136.11].K "sp|Q86U44|MTA70_HUMAN,tr|F5H6D8|F5H6D8_HUMAN,tr|H0YFV6|H0YFV6_HUMAN,tr|B4DTN4|B4DTN4_HUMAN" 4 1114.5606 0.02 12858 12110 2 1114.560616 558.2876 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 6 2620.6 - 1.13E+07 - - - 0.0126 - 2.208 0.565 - 405.8 1 2 0 0 11 0 0 0 1.74E+07 8.83E+08 - - - 5.3569 0.9874 221125_WJC_METTL3_EV_vs_WT_F02.12111.12111.2 0.687 12-Jun R.LDLEDVK[136.11].N "sp|P82094|TMF1_HUMAN,tr|A0A2R8Y7M0|A0A2R8Y7M0_HUMAN" 2 838.4527 0.64 12859 12111 2 838.451945 420.2337 TATA element modulatory factor OS=Homo sapiens OX=9606 GN=TMF1 PE=1 SV=2 4.03 2620.8 - 992505 - - - -0.9589 - 1.3 0.095 - 104.9 1 2 0 -0.0008 7 0 0 0 1.64E+07 2.57E+07 - - - 0.5737 0.9941 221125_WJC_METTL3_EV_vs_WT_F02.12112.12112.2 0.434 18-Jul K.EVPAVPETLK[136.11].K sp|P18124|RL7_HUMAN 1 1089.6161 3.37 12860 12112 2 1089.61568 545.8153 60S ribosomal protein L7 OS=Homo sapiens OX=9606 GN=RPL7 PE=1 SV=1 4.53 2620.8 - 4.31E+06 - - - -0.4093 - 1.068 0.239 - 61.7 1 2 0 -0.0004 10 0 0 0 5.89E+08 1.74E+08 - - - 0.9897 0.9995 221125_WJC_METTL3_EV_vs_WT_F02.12115.12115.2 0.0019 20-Aug K.YLVNPEGQVVK[136.11].F "sp|Q8TED1|GPX8_HUMAN,tr|E7ETY7|E7ETY7_HUMAN" 2 1252.6907 0.88 12863 12115 2 1252.689628 627.3526 Probable glutathione peroxidase 8 OS=Homo sapiens OX=9606 GN=GPX8 PE=1 SV=2 6 2621.1 - 237318 - - - -0.8462 - 1.461 0.407 - 183.6 1 2 0 -0.0011 11 0 0 0 5.05E+06 5.74E+06 - - - 3.0724 0.9983 221125_WJC_METTL3_EV_vs_WT_F02.12118.12118.2 0.000605 18-Nov K.IPVGPETLGR[166.11].L "sp|P06576|ATPB_HUMAN,tr|F8W079|F8W079_HUMAN,tr|H0YH81|H0YH81_HUMAN" 3 1047.5952 2.27 12864 12118 2 1047.595086 524.8049 "ATP synthase subunit beta, mitochondrial OS=Homo sapiens OX=9606 GN=ATP5F1B PE=1 SV=3" 6 2621.5 - 6.08E+06 - - - -0.1231 - 1.884 0.153 - 426.5 1 2 0 -0.0001 10 0 0 0 1.38E+09 6.08E+08 - - - 1.939 0.9997 221125_WJC_METTL3_EV_vs_WT_F02.12119.12119.2 0.0151 16-Sep R.LLSPLSSAR[166.11].L "tr|E9PAU2|E9PAU2_HUMAN,tr|A0A087WZ13|A0A087WZ13_HUMAN" 2 952.5581 0.87 12865 12119 2 952.557736 477.2863 Ribonucleoprotein PTB-binding 1 OS=Homo sapiens OX=9606 GN=RAVER1 PE=1 SV=1 9.75 2621.6 - 3.24E+06 - - - -0.3832 - 1.86 0.36 - 301.5 1 2 0 -0.0004 9 0 0 0 1.73E+09 1.98E+09 - - - 3.4952 0.9994 221125_WJC_METTL3_EV_vs_WT_F02.12120.12120.2 0.000668 16-Sep R.TLYVGNLSR[166.11].D "sp|Q01085|TIAR_HUMAN,sp|P31483|TIA1_HUMAN,tr|F8W8I6|F8W8I6_HUMAN,tr|C9JTN7|C9JTN7_HUMAN,tr|E7ETC0|E7ETC0_HUMAN,tr|E5RG67|E5RG67_HUMAN,tr|E5RGV5|E5RGV5_HUMAN" 7 1031.5639 1.5 12866 12120 2 1031.564302 516.7892 Nucleolysin TIAR OS=Homo sapiens OX=9606 GN=TIAL1 PE=1 SV=1 8.41 2621.6 - 1.76E+06 - - - 0.3761 - 1.456 0.385 - 284.1 1 2 0 0.0004 9 0 0 0 1.87E+08 1.24E+08 - - - 2.9714 0.9998 221125_WJC_METTL3_EV_vs_WT_F02.12125.12125.2 0.0254 20-Oct R.IEEGTYGVVYR[166.11].A "sp|P21127|CD11B_HUMAN,sp|Q9UQ88|CD11A_HUMAN,tr|Q5QPR4|Q5QPR4_HUMAN,tr|A0A0D9SER5|A0A0D9SER5_HUMAN,tr|A0A0D9SEN2|A0A0D9SEN2_HUMAN,tr|Q5QPR3|Q5QPR3_HUMAN,tr|A0A0D9SEI3|A0A0D9SEI3_HUMAN" 7 1294.6433 0.86 12871 12125 2 1294.643884 648.3289 Cyclin-dependent kinase 11B OS=Homo sapiens OX=9606 GN=CDK11B PE=1 SV=4 4.53 2622.3 - 312634 - - - 0.4611 - 1.94 0.416 - 341 1 2 0 0.0006 11 0 0 0 7.53E+06 8.81E+06 - - - 3.9061 0.9986 221125_WJC_METTL3_EV_vs_WT_F02.12128.12128.2 0.705 14-Jul K.FSVSPVVR.V sp|P13639|EF2_HUMAN 1 889.5022 0.38 12872 12128 2 889.500964 445.7584 Elongation factor 2 OS=Homo sapiens OX=9606 GN=EEF2 PE=1 SV=4 9.75 2622.7 - 8.41E+06 - - - -1.3356 - 1.432 0.305 - 126.1 1 2 0 -0.0012 8 0 0 0 3.35E+08 8.71E+08 - - - 2.3763 0.9973 221125_WJC_METTL3_EV_vs_WT_F02.12129.12129.2 0.0151 18-Jul K.NGQDLGVAFK[136.11].L "sp|Q00839|HNRPU_HUMAN,tr|A0A1W2PQL0|A0A1W2PQL0_HUMAN,tr|A0A1W2PPL4|A0A1W2PPL4_HUMAN,tr|A0A1W2PQ74|A0A1W2PQ74_HUMAN,tr|Q5RI18|Q5RI18_HUMAN,tr|A0A1W2PP35|A0A1W2PP35_HUMAN,tr|A0A1W2PPS1|A0A1W2PPS1_HUMAN,tr|A0A1W2PRZ7|A0A1W2PRZ7_HUMAN,tr|A0A1W2PPH7|A0A1W2PPH7_HUMAN,tr|A0A1W2PP34|A0A1W2PP34_HUMAN,tr|A0A1X7SBS1|A0A1X7SBS1_HUMAN" 11 1055.5491 0.98 12873 12129 2 1055.546449 528.7818 Heterogeneous nuclear ribonucleoprotein U OS=Homo sapiens OX=9606 GN=HNRNPU PE=1 SV=6 5.84 2622.7 - 921582 - - - -2.52 - 1.594 0.293 - 118.9 1 2 0 -0.0027 10 0 0 0 1.73E+07 1.76E+07 - - - 2.5057 0.9981 221125_WJC_METTL3_EV_vs_WT_F02.12130.12130.2 0.0382 16-Jul R.LLSPLSSAR.L "tr|E9PAU2|E9PAU2_HUMAN,tr|A0A087WZ13|A0A087WZ13_HUMAN" 2 942.5498 0.87 12874 12130 2 942.548747 472.2822 Ribonucleoprotein PTB-binding 1 OS=Homo sapiens OX=9606 GN=RAVER1 PE=1 SV=1 9.75 2622.8 - 4.42E+06 - - - -1.1501 - 1.51 0.241 - 153.5 1 2 0 -0.0011 9 0 0 0 1.73E+09 1.98E+09 - - - 2.0129 0.9951 221125_WJC_METTL3_EV_vs_WT_F02.12137.12137.2 0.0595 18-Sep K.QSLPPGLAVK[136.11].E sp|P63173|RL38_HUMAN 1 1016.611 1.16 12879 12137 2 1016.610552 509.3128 60S ribosomal protein L38 OS=Homo sapiens OX=9606 GN=RPL38 PE=1 SV=2 8.75 2623.6 - 1.26E+06 - - - -0.422 - 1.346 0.171 - 233 1 2 0 -0.0004 10 0 0 0 9.55E+07 8.20E+07 - - - 1.1333 0.9999 221125_WJC_METTL3_EV_vs_WT_F02.12138.12138.2 0.000456 20-Nov K.VVLIGDSGVGK.S "sp|Q15907|RB11B_HUMAN,sp|P62491|RB11A_HUMAN,tr|B4DQU5|B4DQU5_HUMAN,tr|H3BMH2|H3BMH2_HUMAN,tr|H3BSC1|H3BSC1_HUMAN" 5 1042.6023 1.01 12880 12138 2 1042.602043 522.3084 Ras-related protein Rab-11B OS=Homo sapiens OX=9606 GN=RAB11B PE=1 SV=4 5.81 2623.7 - 1.13E+06 - - - -0.2081 - 2.262 0.499 - 440.8 1 2 0 -0.0002 11 0 0 0 9.64E+08 9.51E+08 - - - 4.9347 0.9933 221125_WJC_METTL3_EV_vs_WT_F02.12139.12139.2 2 12-Jul R.LDLEDVK.N "sp|P82094|TMF1_HUMAN,tr|A0A2R8Y7M0|A0A2R8Y7M0_HUMAN" 2 830.4385 0.61 12881 12139 2 830.4368 416.2266 TATA element modulatory factor OS=Homo sapiens OX=9606 GN=TMF1 PE=1 SV=2 4.03 2623.8 - 1.11E+06 - - - -2.1061 - 1.47 0.169 - 129 1 2 0 -0.0017 7 0 0 0 1.48E+07 2.43E+07 - - - 1.5094 0.9906 221125_WJC_METTL3_EV_vs_WT_F02.12144.12144.2 0.255 12-Jun K.QWDYYAR.R "sp|Q6UN15|FIP1_HUMAN,tr|H0Y8P7|H0Y8P7_HUMAN" 2 1000.4403 0.91 12884 12144 2 1000.442299 501.2274 Pre-mRNA 3'-end-processing factor FIP1 OS=Homo sapiens OX=9606 GN=FIP1L1 PE=1 SV=1 5.83 2624.4 - 2.54E+06 - - - 2.0181 - 1.156 0.238 - 144.2 1 2 0 0.002 7 0 0 0 1.97E+07 2.18E+07 - - - 1.2576 0.9999 221125_WJC_METTL3_EV_vs_WT_F02.12146.12146.2 4.56E-06 22-Oct R.MVPAGMGAGLER[166.11].M "sp|P52272|HNRPM_HUMAN,tr|M0R2I7|M0R2I7_HUMAN,tr|A0A087X0X3|A0A087X0X3_HUMAN,tr|M0QZM1|M0QZM1_HUMAN" 4 1197.5874 1.39 12886 12146 2 1197.586939 599.801 Heterogeneous nuclear ribonucleoprotein M OS=Homo sapiens OX=9606 GN=HNRNPM PE=1 SV=3 5.75 2624.6 - 1.79E+06 - - - -0.3591 - 1.757 0.541 - 393.2 1 2 0 -0.0004 12 0 0 0 5.88E+08 4.25E+08 - - - 4.5196 0.9997 221125_WJC_METTL3_EV_vs_WT_F02.12148.12148.2 0.0145 20-Oct R.IEEGTYGVVYR.A "sp|P21127|CD11B_HUMAN,sp|Q9UQ88|CD11A_HUMAN,tr|Q5QPR4|Q5QPR4_HUMAN,tr|A0A0D9SER5|A0A0D9SER5_HUMAN,tr|A0A0D9SEN2|A0A0D9SEN2_HUMAN,tr|Q5QPR3|Q5QPR3_HUMAN,tr|A0A0D9SEI3|A0A0D9SEI3_HUMAN" 7 1284.635 0.86 12888 12148 2 1284.633459 643.3248 Cyclin-dependent kinase 11B OS=Homo sapiens OX=9606 GN=CDK11B PE=1 SV=4 4.53 2624.8 - 339882 - - - -1.2128 - 2.022 0.417 - 276.9 1 2 0 -0.0016 11 0 0 0 7.62E+06 8.81E+06 - - - 4.0252 0.9954 221125_WJC_METTL3_EV_vs_WT_F02.12154.12154.2 0.149 20-Aug R.AIILAAAPGEK[136.11].L "sp|P26358|DNMT1_HUMAN,tr|A0A7I2V5D0|A0A7I2V5D0_HUMAN,tr|A0A7I2V5F1|A0A7I2V5F1_HUMAN,tr|A0A7I2YQA8|A0A7I2YQA8_HUMAN,tr|A0A7I2YQQ0|A0A7I2YQQ0_HUMAN,tr|K7ENW7|K7ENW7_HUMAN,tr|A0A7I2V490|A0A7I2V490_HUMAN" 7 1060.6372 5.94 12892 12154 2 1060.636166 531.3259 DNA (cytosine-5)-methyltransferase 1 OS=Homo sapiens OX=9606 GN=DNMT1 PE=1 SV=2 6.05 2625.8 - 557355 - - - -0.9711 - 1.575 0.137 - 147.6 1 2 0 -0.001 11 0 0 0 1.91E+08 3.22E+07 - - - 1.2814 0.9996 221125_WJC_METTL3_EV_vs_WT_F02.12155.12155.2 0.000455 18-Jul R.AYTSETYLMK[136.11].H "sp|Q5T0B9|ZN362_HUMAN,sp|Q8TF68|ZN384_HUMAN,tr|A0A804HJE2|A0A804HJE2_HUMAN" 3 1213.578 0.21 12893 12155 2 1213.578581 607.7963 Zinc finger protein 362 OS=Homo sapiens OX=9606 GN=ZNF362 PE=1 SV=1 6.04 2625.9 - 201787 - - - 0.4573 - 1.328 0.474 - 120.4 1 2 0 0.0006 10 0 0 0 1.51E+06 7.06E+06 - - - 3.3336 0.9846 221125_WJC_METTL3_EV_vs_WT_F02.12158.12158.2 3.06E-05 18-Nov R.PVIAC[160.03]SVTIK[136.11].E "sp|P55769|NH2L1_HUMAN,tr|B1AHD1|B1AHD1_HUMAN,tr|A0A3B3IUA2|A0A3B3IUA2_HUMAN,tr|A0A3B3IRU2|A0A3B3IRU2_HUMAN" 4 1094.6249 1.79 12894 12158 2 1094.62684 548.3197 NHP2-like protein 1 OS=Homo sapiens OX=9606 GN=SNU13 PE=1 SV=3 8.64 2626.3 - 1.50E+06 - - - 1.7568 - 2.027 0.503 - 360.6 1 1 0 0.0019 10 0 0 0 8.40E+07 4.68E+07 - - - 4.7278 0.804 221125_WJC_METTL3_EV_vs_WT_F02.12163.12163.2 6.3 14-May K.KELEGSGK[136.11].L sp|P08183|MDR1_HUMAN 1 854.4589 - 12897 12163 2 854.459062 428.2367 ATP-dependent translocase ABCB1 OS=Homo sapiens OX=9606 GN=ABCB1 PE=1 SV=3 6.14 2626.9 - 5.60E+06 - - - 0.1931 - 0.936 0 - 85.6 3 2 0 0.0002 8 0 0 0 - - - - - -1.3717 0.9988 221125_WJC_METTL3_EV_vs_WT_F02.12164.12164.2 0.0252 14-Aug K.LAEEIPLK.L "sp|Q9Y6M1|IF2B2_HUMAN,tr|F8W930|F8W930_HUMAN" 2 911.5328 1.66 12898 12164 2 911.532653 456.7737 Insulin-like growth factor 2 mRNA-binding protein 2 OS=Homo sapiens OX=9606 GN=IGF2BP2 PE=1 SV=2 4.53 2626.9 - 2.79E+06 - - - -0.1437 - 1.498 0.265 - 187.8 1 2 0 -0.0001 8 0 0 0 2.48E+08 1.50E+08 - - - 2.2171 0.9639 221125_WJC_METTL3_EV_vs_WT_F02.12165.12165.2 2.36 12-Jun K.LTFISGR.T "sp|Q15005|SPCS2_HUMAN,tr|E9PI68|E9PI68_HUMAN,tr|A0A087WUC6|A0A087WUC6_HUMAN,tr|E9PRB9|E9PRB9_HUMAN,tr|E9PL01|E9PL01_HUMAN" 5 792.4494 0.87 12899 12165 2 792.45163 397.232 Signal peptidase complex subunit 2 OS=Homo sapiens OX=9606 GN=SPCS2 PE=1 SV=3 9.75 2627.1 - 373371 - - - 2.8292 - 1.441 0.102 - 113.3 4 2 0 0.0022 7 0 0 0 1.20E+08 1.38E+08 - - - 0.6823 0.9999 221125_WJC_METTL3_EV_vs_WT_F02.12168.12168.2 5.48E-06 20-Nov K.VVLIGDSGVGK[136.11].S "sp|Q15907|RB11B_HUMAN,sp|P62491|RB11A_HUMAN,tr|B4DQU5|B4DQU5_HUMAN,tr|H3BMH2|H3BMH2_HUMAN,tr|H3BSC1|H3BSC1_HUMAN" 5 1050.6165 1.02 12900 12168 2 1050.615904 526.3155 Ras-related protein Rab-11B OS=Homo sapiens OX=9606 GN=RAB11B PE=1 SV=4 5.81 2627.4 - 1.26E+07 - - - -0.5292 - 2.506 0.553 - 450.7 1 2 0 -0.0006 11 0 0 0 9.59E+08 9.37E+08 - - - 5.6106 0.9927 221125_WJC_METTL3_EV_vs_WT_F02.12174.12174.2 1.21 16-Sep R.LEAC[160.03]LEELR[166.11].R "sp|Q3KP66|INAVA_HUMAN,tr|C9JAT8|C9JAT8_HUMAN" 2 1141.5677 0.62 12904 12174 2 1141.568078 571.7911 Innate immunity activator protein OS=Homo sapiens OX=9606 GN=INAVA PE=1 SV=2 4.25 2628.1 - 332618 - - - 0.3486 - 1.956 0.003 - 269.2 2 2 0 0.0004 9 0 0 0 6.44E+07 1.04E+08 - - - 0.8695 0.9998 221125_WJC_METTL3_EV_vs_WT_F02.12177.12177.2 0.0491 18-Nov R.LAEVEAALEK.Q sp|Q15149|PLEC_HUMAN 1 1071.5812 0.34 12907 12177 2 1071.581394 536.7979 Plectin OS=Homo sapiens OX=9606 GN=PLEC PE=1 SV=3 4.25 2628.5 - 1.37E+06 - - - 0.1894 - 2.265 0.338 - 304.2 1 2 0 0.0002 10 0 0 0 5.38E+07 1.59E+08 - - - 3.8195 0.9931 221125_WJC_METTL3_EV_vs_WT_F02.12183.12183.2 8.23E-05 18-Dec R.PVIAC[160.03]SVTIK.E "sp|P55769|NH2L1_HUMAN,tr|B1AHD1|B1AHD1_HUMAN,tr|A0A3B3IUA2|A0A3B3IUA2_HUMAN,tr|A0A3B3IRU2|A0A3B3IRU2_HUMAN" 4 1086.6107 1.81 12911 12183 2 1086.61125 544.3126 NHP2-like protein 1 OS=Homo sapiens OX=9606 GN=SNU13 PE=1 SV=3 8.64 2629.1 - 2.56E+06 - - - 0.4905 - 2.211 0.52 - 460.2 1 1 0 0.0005 10 0 0 0 8.57E+07 4.74E+07 - - - 5.0963 0.9471 221125_WJC_METTL3_EV_vs_WT_F02.12184.12184.2 0.231 18-Aug K.LPSDVVTAVR.G sp|P04181|OAT_HUMAN 1 1055.5975 1.15 12912 12184 2 1055.592964 528.806 "Ornithine aminotransferase, mitochondrial OS=Homo sapiens OX=9606 GN=OAT PE=1 SV=1" 5.84 2629.2 - 1.68E+06 - - - -4.3056 - 1.345 0.172 - 141.1 1 2 0 -0.0045 10 0 0 0 1.05E+08 9.06E+07 - - - 1.1373 0.9976 221125_WJC_METTL3_EV_vs_WT_F02.12188.12188.2 0.227 14-Jul R.TIAPIIGR[166.11].T sp|Q99459|CDC5L_HUMAN 1 849.5312 1.29 12914 12188 2 849.530722 425.7729 Cell division cycle 5-like protein OS=Homo sapiens OX=9606 GN=CDC5L PE=1 SV=2 9.41 2629.7 - 4.65E+06 - - - -0.5132 - 1.283 0.253 - 176.2 1 2 0 -0.0004 8 0 0 0 3.18E+08 2.47E+08 - - - 1.6611 0.9991 221125_WJC_METTL3_EV_vs_WT_F02.12189.12189.2 0.00286 14-Aug K.LAEEIPLK[136.11].L "sp|Q9Y6M1|IF2B2_HUMAN,tr|F8W930|F8W930_HUMAN" 2 919.547 1.66 12915 12189 2 919.546476 460.7808 Insulin-like growth factor 2 mRNA-binding protein 2 OS=Homo sapiens OX=9606 GN=IGF2BP2 PE=1 SV=2 4.53 2629.8 - 4.47E+06 - - - -0.5524 - 1.605 0.278 - 185.2 1 2 0 -0.0005 8 0 0 0 2.48E+08 1.50E+08 - - - 2.5211 0.9843 221125_WJC_METTL3_EV_vs_WT_F02.12190.12190.2 9.17 12-Jun K.LQIELGK[136.11].C "sp|P20700|LMNB1_HUMAN,sp|Q03252|LMNB2_HUMAN,tr|A0A0D9SFY5|A0A0D9SFY5_HUMAN,tr|E9PBF6|E9PBF6_HUMAN,tr|A0A0D9SFE5|A0A0D9SFE5_HUMAN" 5 807.4946 1.17 12916 12190 2 807.494285 404.7546 Lamin-B1 OS=Homo sapiens OX=9606 GN=LMNB1 PE=1 SV=2 6 2629.9 - 993411 - - - -0.3331 - 1.559 0.001 - 107 2 2 0 -0.0003 7 0 0 0 8.71E+07 7.45E+07 - - - 0.3208 0.9971 221125_WJC_METTL3_EV_vs_WT_F02.12194.12194.2 0.0904 12-Jun K.ITIPYGR.K "sp|Q9UBU9|NXF1_HUMAN,tr|E9PLA7|E9PLA7_HUMAN,tr|E9PIN3|E9PIN3_HUMAN" 3 818.465 2.71 12919 12194 2 818.465997 410.2398 Nuclear RNA export factor 1 OS=Homo sapiens OX=9606 GN=NXF1 PE=1 SV=1 8.75 2630.4 - 5.02E+06 - - - 1.1717 - 1.392 0.228 - 123.9 1 2 0 0.001 7 0 0 0 1.20E+09 4.45E+08 - - - 1.7727 0.984 221125_WJC_METTL3_EV_vs_WT_F02.12196.12196.2 3.67 18-Oct K.PAASPLTSLR.Q sp|Q92615|LAR4B_HUMAN 1 1011.5713 1.36 12920 12196 2 1011.571407 506.7929 La-related protein 4B OS=Homo sapiens OX=9606 GN=LARP4B PE=1 SV=3 10.18 2630.6 - 1.80E+06 - - - 0.1107 - 2.079 0.355 - 470.2 1 1 0 0.0001 10 0 0 0 1.35E+08 9.96E+07 - - - 3.7059 0.9988 221125_WJC_METTL3_EV_vs_WT_F02.12200.12200.2 0.0424 14-Jul K.ASLSLIEK.Y "sp|P52292|IMA1_HUMAN,tr|A0A7I2YQE1|A0A7I2YQE1_HUMAN,tr|A0A7I2V487|A0A7I2V487_HUMAN,tr|A0A7I2V351|A0A7I2V351_HUMAN" 4 859.5015 0.9 12922 12200 2 859.501736 430.758 Importin subunit alpha-1 OS=Homo sapiens OX=9606 GN=KPNA2 PE=1 SV=1 6.05 2631 - 8.97E+06 - - - 0.2932 - 1.581 0.242 - 164.1 1 2 0 0.0003 8 0 0 0 3.34E+08 3.72E+08 - - - 2.2098 0.9967 221125_WJC_METTL3_EV_vs_WT_F02.12201.12201.2 0.0511 14-Jul K.ASLSLIEK[136.11].Y "sp|P52292|IMA1_HUMAN,tr|A0A7I2YQE1|A0A7I2YQE1_HUMAN,tr|A0A7I2V487|A0A7I2V487_HUMAN,tr|A0A7I2V351|A0A7I2V351_HUMAN" 4 867.5157 0.89 12923 12201 2 867.514904 434.7651 Importin subunit alpha-1 OS=Homo sapiens OX=9606 GN=KPNA2 PE=1 SV=1 6.05 2631.1 - 6.55E+06 - - - -0.8991 - 1.336 0.215 - 176.1 1 2 0 -0.0008 8 0 0 0 3.30E+08 3.71E+08 - - - 1.5024 0.9966 221125_WJC_METTL3_EV_vs_WT_F02.12202.12202.2 0.0105 12-May K.AWEEYYK[136.11].K "sp|Q92945|FUBP2_HUMAN,sp|Q92945|FUBP2_HUMAN,sp|Q96AE4|FUBP1_HUMAN,tr|E9PEB5|E9PEB5_HUMAN,tr|M0R263|M0R263_HUMAN,tr|M0R3J3|M0R3J3_HUMAN,tr|M0R0C6|M0R0C6_HUMAN,tr|M0R0C6|M0R0C6_HUMAN,tr|M0QYG1|M0QYG1_HUMAN,tr|A0A087WTP3|A0A087WTP3_HUMAN,tr|M0R251|M0R251_HUMAN" 11 995.448 1.07 12924 12202 2 995.448428 498.7313 Far upstream element-binding protein 2 OS=Homo sapiens OX=9606 GN=KHSRP PE=1 SV=4 4.53 2631.1 - 6.96E+06 - - - 0.432 - 1.168 0.258 - 97.3 1 2 0 0.0004 7 0 0 0 1.75E+08 1.64E+08 - - - 1.4385 0.9994 221125_WJC_METTL3_EV_vs_WT_F02.12209.12209.2 0.00986 18-Oct K.LPSDVVTAVR[166.11].G sp|P04181|OAT_HUMAN 1 1065.6058 1.15 12927 12209 2 1065.605714 533.8102 "Ornithine aminotransferase, mitochondrial OS=Homo sapiens OX=9606 GN=OAT PE=1 SV=1" 5.84 2632 - 524218 - - - -0.061 - 1.63 0.339 - 232 1 2 0 -0.0001 10 0 0 0 1.05E+08 9.06E+07 - - - 2.9086 0.9832 221125_WJC_METTL3_EV_vs_WT_F02.12214.12214.2 0.156 18-Aug K.LANLINAEER[166.11].R "sp|P52701|MSH6_HUMAN,tr|A0A494C0M1|A0A494C0M1_HUMAN,tr|A0A087WWJ1|A0A087WWJ1_HUMAN" 3 1151.6174 0.59 12930 12214 2 1151.622455 576.816 DNA mismatch repair protein Msh6 OS=Homo sapiens OX=9606 GN=MSH6 PE=1 SV=2 4.53 2632.6 - 363809 - - - 4.3834 - 1.796 0.195 - 235.9 1 2 0 0.005 10 0 0 0 5.15E+06 8.76E+06 - - - 2.1142 0.9994 221125_WJC_METTL3_EV_vs_WT_F02.12218.12218.2 0.0142 14-Jul R.TVITEEFK.V sp|Q96I24|FUBP3_HUMAN 1 965.507 1.85 12932 12218 2 965.507852 483.7608 Far upstream element-binding protein 3 OS=Homo sapiens OX=9606 GN=FUBP3 PE=1 SV=2 4.53 2633.1 - 3.63E+06 - - - 0.9208 - 1.484 0.383 - 153.9 1 2 0 0.0009 8 0 0 0 9.03E+08 4.88E+08 - - - 3.0601 0.9968 221125_WJC_METTL3_EV_vs_WT_F02.12219.12219.2 1.26 22-Aug K.GLSPAMSPALQR[166.11].L sp|Q96DF8|ESS2_HUMAN 1 1236.6524 2.34 12933 12219 2 1236.65194 619.3335 Splicing factor ESS-2 homolog OS=Homo sapiens OX=9606 GN=ESS2 PE=1 SV=1 9.75 2633.2 - 305186 - - - -0.3817 - 1.156 0.272 - 106.9 1 2 0 -0.0005 12 0 0 0 4.24E+07 1.82E+07 - - - 1.4313 0.9131 221125_WJC_METTL3_EV_vs_WT_F02.12220.12220.2 0.00211 18-Oct K.PAASPLTSLR[166.11].Q sp|Q92615|LAR4B_HUMAN 1 1021.5796 1.36 12934 12220 2 1021.581722 511.7971 La-related protein 4B OS=Homo sapiens OX=9606 GN=LARP4B PE=1 SV=3 10.18 2633.3 - 1.29E+06 - - - 2.1114 - 1.83 0.279 - 312.8 1 1 0 0.0022 10 0 0 0 1.50E+08 1.10E+08 - - - 2.7878 0.9993 221125_WJC_METTL3_EV_vs_WT_F02.12221.12221.2 0.0144 22-Aug K.GLSPAMSPALQR.L sp|Q96DF8|ESS2_HUMAN 1 1226.6441 2.34 12935 12221 2 1226.644838 614.3293 Splicing factor ESS-2 homolog OS=Homo sapiens OX=9606 GN=ESS2 PE=1 SV=1 9.75 2633.4 - 316886 - - - 0.5674 - 1.616 0.332 - 211.7 1 2 0 0.0007 12 0 0 0 4.24E+07 1.82E+07 - - - 2.7558 0.9992 221125_WJC_METTL3_EV_vs_WT_F02.12224.12224.2 0.0144 14-Jul K.AVLQEFGR[166.11].L "sp|Q9Y394|DHRS7_HUMAN,tr|H0YJ66|H0YJ66_HUMAN,tr|H0YJE4|H0YJE4_HUMAN" 3 928.5006 2.02 12936 12224 2 928.499923 465.2576 Dehydrogenase\reductase SDR family member 7 OS=Homo sapiens OX=9606 GN=DHRS7 PE=1 SV=1 6.05 2633.8 - 2.03E+06 - - - -0.7141 - 1.586 0.299 - 175 1 2 0 -0.0007 8 0 0 0 2.46E+08 1.22E+08 - - - 2.6402 0.9971 221125_WJC_METTL3_EV_vs_WT_F02.12230.12230.2 0.93 14-Aug K.NIILGGVK[136.11].A "sp|P22314|UBA1_HUMAN,tr|Q5JRS3|Q5JRS3_HUMAN,tr|Q5JRS2|Q5JRS2_HUMAN,tr|Q5JRS0|Q5JRS0_HUMAN,tr|Q5JRS1|Q5JRS1_HUMAN,tr|Q5JRR9|Q5JRR9_HUMAN" 6 820.5262 0.56 12940 12230 2 820.526062 411.2704 Ubiquitin-like modifier-activating enzyme 1 OS=Homo sapiens OX=9606 GN=UBA1 PE=1 SV=3 8.75 2634.5 - 2.87E+06 - - - -0.1548 - 1.67 0.122 - 210.8 1 2 0 -0.0001 8 0 0 0 5.31E+07 9.50E+07 - - - 1.4887 0.9985 221125_WJC_METTL3_EV_vs_WT_F02.12231.12231.2 1.18 12-Aug K.VDLVLEK.E "sp|P17900|SAP3_HUMAN,tr|E5RJD0|E5RJD0_HUMAN,tr|H0YBY3|H0YBY3_HUMAN" 3 814.48 17.52 12941 12231 2 814.480135 408.2473 Ganglioside GM2 activator OS=Homo sapiens OX=9606 GN=GM2A PE=1 SV=4 4.37 2634.5 - 3.24E+06 - - - 0.1412 - 1.901 0.13 - 263.3 1 2 0 0.0001 7 0 0 0 8.78E+07 5.01E+06 - - - 2.0366 0.98 221125_WJC_METTL3_EV_vs_WT_F02.12239.12239.2 0.571 14-Aug K.EFIEAEMK[136.11].L "sp|Q13423|NNTM_HUMAN,tr|E9PCX7|E9PCX7_HUMAN,tr|A0A590UK15|A0A590UK15_HUMAN,tr|A0A590UJM2|A0A590UJM2_HUMAN,tr|A0A590UK29|A0A590UK29_HUMAN,tr|A0A590UJI3|A0A590UJI3_HUMAN" 6 1003.4776 0 12946 12239 2 1003.478268 502.7461 "NAD(P) transhydrogenase, mitochondrial OS=Homo sapiens OX=9606 GN=NNT PE=1 SV=3" 4.25 2635.5 - 515701 - - - 0.6816 - 1.265 0.068 - 168.7 1 2 0 0.0007 8 0 0 0 5.42E+04 1.71E+07 - - - 0.252 0.9993 221125_WJC_METTL3_EV_vs_WT_F02.12246.12246.2 0.0259 18-Aug K.YLDVC[160.03]PVSAR.Q sp|O15047|SET1A_HUMAN 1 1178.5754 0.02 12951 12246 2 1178.574353 590.295 Histone-lysine N-methyltransferase SETD1A OS=Homo sapiens OX=9606 GN=SETD1A PE=1 SV=3 5.83 2636.4 - 375705 - - - -0.8833 - 1.505 0.365 - 220.8 1 2 0 -0.001 10 0 0 0 1.02E+07 5.28E+08 - - - 2.8776 0.9963 221125_WJC_METTL3_EV_vs_WT_F02.12247.12247.2 0.454 16-Aug R.LLGLTGSTK[136.11].Q sp|O43819|SCO2_HUMAN 1 896.5422 1.1 12952 12247 2 896.543422 449.2784 "Protein SCO2 homolog, mitochondrial OS=Homo sapiens OX=9606 GN=SCO2 PE=1 SV=3" 8.75 2636.4 - 1.16E+06 - - - 1.3262 - 1.645 0.16 - 113 1 2 0 0.0012 9 0 0 0 3.29E+08 2.98E+08 - - - 1.6624 0.9971 221125_WJC_METTL3_EV_vs_WT_F02.12250.12250.2 0.00355 22-Jul K.ILIANTGMDTDK[136.11].L "sp|P78371|TCPB_HUMAN,tr|F8VQ14|F8VQ14_HUMAN,tr|F5GWF6|F5GWF6_HUMAN" 3 1298.6632 0.56 12953 12250 2 1298.665644 650.3389 T-complex protein 1 subunit beta OS=Homo sapiens OX=9606 GN=CCT2 PE=1 SV=4 4.21 2636.8 - 99398.9 - - - 1.9181 - 1.478 0.278 - 135.6 1 2 0 0.0025 12 0 0 0 3.24E+07 5.74E+07 - - - 2.1215 0.9976 221125_WJC_METTL3_EV_vs_WT_F02.12252.12252.2 0.0585 14-Jun K.GLYPAPLK[136.11].L "sp|P40939|ECHA_HUMAN,tr|A0A2R8YG21|A0A2R8YG21_HUMAN,tr|A0A2R8Y688|A0A2R8Y688_HUMAN,tr|H0YFD6|H0YFD6_HUMAN,tr|A0A2R8Y4F5|A0A2R8Y4F5_HUMAN" 5 865.5153 0.92 12954 12252 2 865.51544 433.7649 "Trifunctional enzyme subunit alpha, mitochondrial OS=Homo sapiens OX=9606 GN=HADHA PE=1 SV=2" 8.59 2637 - 1.28E+06 - - - 0.1733 - 1.382 0.221 - 102.6 1 2 0 0.0001 8 0 0 0 3.84E+08 4.19E+08 - - - 1.649 0.9899 221125_WJC_METTL3_EV_vs_WT_F02.12253.12253.2 1.81 14-Jun K.AVLQEFGR.L "sp|Q9Y394|DHRS7_HUMAN,tr|H0YJ66|H0YJ66_HUMAN,tr|H0YJE4|H0YJE4_HUMAN" 3 918.4923 2.04 12955 12253 2 918.492255 460.2534 Dehydrogenase\reductase SDR family member 7 OS=Homo sapiens OX=9606 GN=DHRS7 PE=1 SV=1 6.05 2637.1 - 1.34E+06 - - - -0.0664 - 1.248 0.14 - 75.1 2 2 0 -0.0001 8 0 0 0 2.50E+08 1.22E+08 - - - 0.6087 0.9989 221125_WJC_METTL3_EV_vs_WT_F02.12259.12259.2 0.012 20-Oct R.VAALGNDPLAR[166.11].L sp|P54259|ATN1_HUMAN 1 1105.6119 3.29 12959 12259 2 1105.614257 553.8132 Atrophin-1 OS=Homo sapiens OX=9606 GN=ATN1 PE=1 SV=3 5.81 2637.8 - 618664 - - - 2.1074 - 1.908 0.326 - 374 1 2 0 0.0023 11 0 0 0 6.16E+07 1.87E+07 - - - 3.1958 0.9978 221125_WJC_METTL3_EV_vs_WT_F02.12262.12262.2 0.922 20-Sep R.VAALGNDPLAR.L sp|P54259|ATN1_HUMAN 1 1095.6037 0.07 12960 12262 2 1095.604096 548.8091 Atrophin-1 OS=Homo sapiens OX=9606 GN=ATN1 PE=1 SV=3 5.81 2638.2 - 1.96E+06 - - - 0.4007 - 1.932 0.126 - 241.7 1 2 0 0.0004 11 0 0 0 1.03E+08 1.45E+09 - - - 1.753 0.9284 221125_WJC_METTL3_EV_vs_WT_F02.12265.12265.2 2.61 14-May K.LFSELGSR.N "sp|P98173|FAM3A_HUMAN,tr|Q5HY75|Q5HY75_HUMAN,tr|D3DWX8|D3DWX8_HUMAN" 3 907.4763 1.31 12962 12265 2 907.4768 454.7454 Protein FAM3A OS=Homo sapiens OX=9606 GN=FAM3A PE=1 SV=2 6 2638.5 - 1.23E+06 - - - 0.5168 - 1.174 0.032 - 58.8 7 2 0 0.0005 8 0 0 0 9.94E+07 7.59E+07 - - - -0.6165 0.9087 221125_WJC_METTL3_EV_vs_WT_F02.12266.12266.2 0.154 16-Aug N.LVIITAGAR.Q "sp|Q9BYZ2|LDH6B_HUMAN,sp|Q6ZMR3|LDH6A_HUMAN,sp|P00338|LDHA_HUMAN,tr|A0A087WUM2|A0A087WUM2_HUMAN,tr|F5GXH2|F5GXH2_HUMAN,tr|F5GYU2|F5GYU2_HUMAN,tr|F5GXY2|F5GXY2_HUMAN" 7 912.5757 1.17 12963 12266 2 912.577042 457.2951 L-lactate dehydrogenase A-like 6B OS=Homo sapiens OX=9606 GN=LDHAL6B PE=1 SV=3 9.75 2638.5 - 1.02E+06 - - - 1.5232 - 1.566 0.28 - 130.9 1 1 0 0.0014 9 0 0 0 4.93E+07 4.22E+07 - - - 2.4062 0.9997 221125_WJC_METTL3_EV_vs_WT_F02.12267.12267.2 0.000308 18-Sep R.TFATALDTTR[166.11].H sp|Q9BT25|HAUS8_HUMAN 1 1105.5643 3.48 12964 12267 2 1105.565151 553.7894 HAUS augmin-like complex subunit 8 OS=Homo sapiens OX=9606 GN=HAUS8 PE=1 SV=3 5.5 2638.6 - 579003 - - - 0.7625 - 1.557 0.454 - 258.1 1 2 0 0.0008 10 0 0 0 7.63E+07 2.19E+07 - - - 3.6299 0.9909 221125_WJC_METTL3_EV_vs_WT_F02.12268.12268.2 0.226 20-Jul K.EITALAPSTMK[136.11].L "sp|P63261|ACTG_HUMAN,sp|P68133|ACTS_HUMAN,sp|P62736|ACTA_HUMAN,sp|P68032|ACTC_HUMAN,sp|P60709|ACTB_HUMAN,sp|P63267|ACTH_HUMAN,tr|A0A2R8YFE2|A0A2R8YFE2_HUMAN,tr|A0A804GS07|A0A804GS07_HUMAN,tr|E7EVS6|E7EVS6_HUMAN,tr|A0A6Q8PFE4|A0A6Q8PFE4_HUMAN,tr|A0A804HKV3|A0A804HKV3_HUMAN,tr|I3L4N8|I3L4N8_HUMAN,tr|A6NL76|A6NL76_HUMAN" 13 1168.6253 0.99 12965 12268 2 1168.627263 585.3199 "Actin, cytoplasmic 2 OS=Homo sapiens OX=9606 GN=ACTG1 PE=1 SV=1" 6.1 2638.8 - 213954 - - - 1.6712 - 1.411 0.156 - 130.9 1 2 0 0.002 11 0 0 0 7.92E+08 7.97E+08 - - - 1.124 0.9978 221125_WJC_METTL3_EV_vs_WT_F02.12271.12271.2 0.0196 20-Aug K.EITALAPSTMK.L "sp|P63261|ACTG_HUMAN,sp|P68133|ACTS_HUMAN,sp|P62736|ACTA_HUMAN,sp|P68032|ACTC_HUMAN,sp|P60709|ACTB_HUMAN,sp|P63267|ACTH_HUMAN,tr|A0A2R8YFE2|A0A2R8YFE2_HUMAN,tr|A0A804GS07|A0A804GS07_HUMAN,tr|E7EVS6|E7EVS6_HUMAN,tr|A0A6Q8PFE4|A0A6Q8PFE4_HUMAN,tr|A0A804HKV3|A0A804HKV3_HUMAN,tr|I3L4N8|I3L4N8_HUMAN,tr|A6NL76|A6NL76_HUMAN" 13 1160.6111 0.99 12966 12271 2 1160.611717 581.3128 "Actin, cytoplasmic 2 OS=Homo sapiens OX=9606 GN=ACTG1 PE=1 SV=1" 6.1 2639.1 - 452837 - - - 0.523 - 1.562 0.207 - 204.6 1 2 0 0.0006 11 0 0 0 7.92E+08 7.98E+08 - - - 1.7762 0.9966 221125_WJC_METTL3_EV_vs_WT_F02.12273.12273.2 0.0449 16-Sep K.ILASAPNWK[136.11].W sp|O00443|P3C2A_HUMAN 1 1006.5691 2.39 12967 12273 2 1006.573037 504.2918 Phosphatidylinositol 4-phosphate 3-kinase C2 domain-containing subunit alpha OS=Homo sapiens OX=9606 GN=PIK3C2A PE=1 SV=2 8.75 2639.4 - 1.49E+06 - - - 3.8954 - 1.712 0.365 - 185.6 1 2 0 0.0039 9 0 0 0 7.31E+07 3.06E+07 - - - 3.2911 0.9987 221125_WJC_METTL3_EV_vs_WT_F02.12275.12275.2 0.00767 16-Aug K.TLPDEVLTK.E "sp|Q9BZZ5|API5_HUMAN,tr|H0YER7|H0YER7_HUMAN,tr|G3V1C3|G3V1C3_HUMAN" 3 1014.5597 2.19 12969 12275 2 1014.56176 508.2871 Apoptosis inhibitor 5 OS=Homo sapiens OX=9606 GN=API5 PE=1 SV=3 4.37 2639.5 - 2.54E+06 - - - 2.0038 - 1.386 0.397 - 166.8 1 2 0 0.002 9 0 0 0 3.29E+08 1.50E+08 - - - 2.917 0.9902 221125_WJC_METTL3_EV_vs_WT_F02.12281.12281.2 1.58E-05 14-Aug K.GILGYTEH.Q "sp|P04406|G3P_HUMAN,tr|E7EUT5|E7EUT5_HUMAN" 2 888.4341 - 12973 12281 2 888.434802 445.2243 Glyceraldehyde-3-phosphate dehydrogenase OS=Homo sapiens OX=9606 GN=GAPDH PE=1 SV=3 5.24 2640.2 - 1.13E+07 - - - 0.7541 - 1.653 0.55 - 197 1 1 0 0.0007 8 0 0 0 - - - - - 4.6189 0.9986 221125_WJC_METTL3_EV_vs_WT_F02.12282.12282.2 0.03 16-Aug R.YLDGLTAER.T sp|P35908|K22E_HUMAN 1 1036.5189 1044.48 12974 12282 2 1036.519307 519.2667 "Keratin, type II cytoskeletal 2 epidermal OS=Homo sapiens OX=9606 GN=KRT2 PE=1 SV=2" 4.37 2640.3 - 4.61E+06 - - - 0.3685 - 1.459 0.266 - 171 1 2 0 0.0004 9 0 0 0 1.81E+10 1.74E+07 - - - 2.0984 0.9999 221125_WJC_METTL3_EV_vs_WT_F02.12283.12283.2 2.69E-06 16-Oct K.MNGMLLNDR[166.11].K "sp|Q13310|PABP4_HUMAN,sp|Q4VXU2|PAP1L_HUMAN,sp|P11940|PABP1_HUMAN,tr|A0A7I2V5W9|A0A7I2V5W9_HUMAN,tr|A0A7I2YQE4|A0A7I2YQE4_HUMAN,tr|A0A7I2V649|A0A7I2V649_HUMAN,tr|B1ANR0|B1ANR0_HUMAN,tr|A0A6Q8JFT6|A0A6Q8JFT6_HUMAN,tr|A0A7I2V4L7|A0A7I2V4L7_HUMAN,tr|H0YCC8|H0YCC8_HUMAN,tr|H0YAR2|H0YAR2_HUMAN,tr|E7ERJ7|E7ERJ7_HUMAN,tr|A0A7I2V598|A0A7I2V598_HUMAN,tr|A0A7I2YQ88|A0A7I2YQ88_HUMAN,tr|H0YEQ8|H0YEQ8_HUMAN,tr|H0Y5F5|H0Y5F5_HUMAN,tr|H0YBN4|H0YBN4_HUMAN,tr|A0A087WTT1|A0A087WTT1_HUMAN,tr|A0A7I2YQ90|A0A7I2YQ90_HUMAN,tr|A0A7I2V4N4|A0A7I2V4N4_HUMAN,tr|E7EQV3|E7EQV3_HUMAN" 21 1072.5033 1.34 12975 12283 2 1072.504049 537.2589 Polyadenylate-binding protein 4 OS=Homo sapiens OX=9606 GN=PABPC4 PE=1 SV=1 5.59 2640.3 - 1.78E+06 - - - 0.6937 - 2.026 0.523 - 409.8 1 2 0 0.0007 9 0 0 0 5.25E+08 3.92E+08 - - - 4.9463 0.9984 221125_WJC_METTL3_EV_vs_WT_F02.12284.12284.2 0.0311 12-Jun R.VAQDWLK[136.11].E "sp|Q16891|MIC60_HUMAN,tr|B9A067|B9A067_HUMAN,tr|A0A087WYS0|A0A087WYS0_HUMAN,tr|C9J406|C9J406_HUMAN,tr|H7C463|H7C463_HUMAN" 5 866.4742 1.35 12976 12284 2 866.475039 434.2444 MICOS complex subunit MIC60 OS=Homo sapiens OX=9606 GN=IMMT PE=1 SV=1 5.81 2640.4 - 1.77E+06 - - - 1.0225 - 1.544 0.245 - 106.4 1 2 0 0.0009 7 0 0 0 5.48E+08 4.05E+08 - - - 2.2266 0.9986 221125_WJC_METTL3_EV_vs_WT_F02.12289.12289.2 0.0136 12-Jul R.VAQDWLK.E "sp|Q16891|MIC60_HUMAN,tr|B9A067|B9A067_HUMAN,tr|A0A087WYS0|A0A087WYS0_HUMAN,tr|C9J406|C9J406_HUMAN,tr|H7C463|H7C463_HUMAN" 5 858.46 1.35 12979 12289 2 858.461229 430.2373 MICOS complex subunit MIC60 OS=Homo sapiens OX=9606 GN=IMMT PE=1 SV=1 5.81 2640.9 - 3.10E+06 - - - 1.4864 - 1.575 0.281 - 160.3 1 2 0 0.0013 7 0 0 0 5.49E+08 4.05E+08 - - - 2.5554 0.9803 221125_WJC_METTL3_EV_vs_WT_F02.12290.12290.2 0.715 16-Oct R.ISASLLDSR.S "sp|O43402|EMC8_HUMAN,tr|M0R1B0|M0R1B0_HUMAN" 2 960.524 9.67 12980 12290 2 960.530661 481.2693 ER membrane protein complex subunit 8 OS=Homo sapiens OX=9606 GN=EMC8 PE=1 SV=1 5.84 2641 - 1.96E+06 - - - 6.9243 - 2.085 0.327 - 359 1 2 0 0.0067 9 0 0 0 1.94E+08 2.00E+07 - - - 3.5799 0.9999 221125_WJC_METTL3_EV_vs_WT_F02.12291.12291.2 5.75E-06 16-Sep K.MNGMLLNDR.K "sp|Q13310|PABP4_HUMAN,sp|Q4VXU2|PAP1L_HUMAN,sp|P11940|PABP1_HUMAN,tr|A0A7I2V5W9|A0A7I2V5W9_HUMAN,tr|A0A7I2YQE4|A0A7I2YQE4_HUMAN,tr|A0A7I2V649|A0A7I2V649_HUMAN,tr|B1ANR0|B1ANR0_HUMAN,tr|A0A6Q8JFT6|A0A6Q8JFT6_HUMAN,tr|A0A7I2V4L7|A0A7I2V4L7_HUMAN,tr|H0YCC8|H0YCC8_HUMAN,tr|H0YAR2|H0YAR2_HUMAN,tr|E7ERJ7|E7ERJ7_HUMAN,tr|A0A7I2V598|A0A7I2V598_HUMAN,tr|A0A7I2YQ88|A0A7I2YQ88_HUMAN,tr|H0YEQ8|H0YEQ8_HUMAN,tr|H0Y5F5|H0Y5F5_HUMAN,tr|H0YBN4|H0YBN4_HUMAN,tr|A0A087WTT1|A0A087WTT1_HUMAN,tr|A0A7I2YQ90|A0A7I2YQ90_HUMAN,tr|A0A7I2V4N4|A0A7I2V4N4_HUMAN,tr|E7EQV3|E7EQV3_HUMAN" 21 1062.495 1.35 12981 12291 2 1062.495278 532.2548 Polyadenylate-binding protein 4 OS=Homo sapiens OX=9606 GN=PABPC4 PE=1 SV=1 5.59 2641.1 - 2.90E+06 - - - 0.2287 - 1.961 0.546 - 387 1 2 0 0.0002 9 0 0 0 5.25E+08 3.90E+08 - - - 5.022 0.9879 221125_WJC_METTL3_EV_vs_WT_F02.12292.12292.2 0.552 16-Sep R.AVMISAIEK[136.11].Q sp|Q15393|SF3B3_HUMAN 1 968.5456 1.38 12982 12292 2 968.54556 485.2801 Splicing factor 3B subunit 3 OS=Homo sapiens OX=9606 GN=SF3B3 PE=1 SV=4 6.05 2641.1 - 2.00E+06 - - - -0.0454 - 1.536 0.028 - 241.3 1 2 0 0 9 0 0 0 2.51E+08 1.82E+08 - - - 0.4894 0.9941 221125_WJC_METTL3_EV_vs_WT_F02.12293.12293.2 1.14 12-Jul K.LADLSLR.L "sp|Q9Y3C0|WASC3_HUMAN,tr|F5GXZ7|F5GXZ7_HUMAN,tr|H0YGN0|H0YGN0_HUMAN,tr|F5GWI9|F5GWI9_HUMAN,tr|F5GZ97|F5GZ97_HUMAN" 5 786.46 1.59 12983 12293 2 786.459882 394.2373 WASH complex subunit 3 OS=Homo sapiens OX=9606 GN=WASHC3 PE=1 SV=1 5.84 2641.2 - 1.54E+06 - - - -0.0903 - 1.508 0.086 - 161.7 1 2 0 -0.0001 7 0 0 0 4.00E+07 2.51E+07 - - - 0.9778 0.9966 221125_WJC_METTL3_EV_vs_WT_F02.12294.12294.2 0.678 14-Aug R.LGMGLVSR.S "sp|Q8N6H7|ARFG2_HUMAN,tr|E9PIY6|E9PIY6_HUMAN,tr|E9PQP3|E9PQP3_HUMAN,tr|G5E9L0|G5E9L0_HUMAN,tr|A0A0D9SF70|A0A0D9SF70_HUMAN" 5 831.4637 0.78 12984 12294 2 831.463827 416.7391 ADP-ribosylation factor GTPase-activating protein 2 OS=Homo sapiens OX=9606 GN=ARFGAP2 PE=1 SV=1 9.75 2641.2 - 786581 - - - 0.2033 - 1.553 0.139 - 132.5 1 2 0 0.0002 8 0 0 0 5.90E+07 7.52E+07 - - - 1.3952 0.9581 221125_WJC_METTL3_EV_vs_WT_F02.12295.12295.2 0.793 14-Jun K.C[160.03]SVLSTLR[166.11].G sp|O43824|GTPB6_HUMAN 1 944.4989 1.15 12985 12295 2 944.497901 473.2567 Putative GTP-binding protein 6 OS=Homo sapiens OX=9606 GN=GTPBP6 PE=1 SV=4 8.25 2641.3 - 1.93E+06 - - - -1.0281 - 1.099 0.064 - 83.8 1 2 0 -0.001 8 0 0 0 2.36E+07 2.06E+07 - - - -0.2019 0.9332 221125_WJC_METTL3_EV_vs_WT_F02.12296.12296.2 0.0928 18-Nov V.PAGMGAGLER.M "sp|P52272|HNRPM_HUMAN,tr|M0R2I7|M0R2I7_HUMAN,tr|A0A087X0X3|A0A087X0X3_HUMAN,tr|M0QZM1|M0QZM1_HUMAN" 4 957.4702 0.43 12986 12296 2 957.466947 479.7424 Heterogeneous nuclear ribonucleoprotein M OS=Homo sapiens OX=9606 GN=HNRNPM PE=1 SV=3 6.43 2641.4 - 356791 - - - -3.3975 - 2.33 0.364 - 355 1 1 0 -0.0033 10 0 0 0 3.36E+07 7.73E+07 - - - 4.0896 0.986 221125_WJC_METTL3_EV_vs_WT_F02.12300.12300.2 5.17 14-Jul R.LVSLIGSK.T "sp|P25786|PSA1_HUMAN,tr|F5GX11|F5GX11_HUMAN" 2 815.5117 0.85 12988 12300 2 815.512155 408.7631 Proteasome subunit alpha type-1 OS=Homo sapiens OX=9606 GN=PSMA1 PE=1 SV=1 8.75 2641.9 - 1.00E+06 - - - 0.6143 - 1.259 0.1 - 130.6 1 2 0 0.0005 8 0 0 0 2.67E+08 3.13E+08 - - - 0.4741 0.9998 221125_WJC_METTL3_EV_vs_WT_F02.12302.12302.2 0.000378 14-Sep R.LGMGLVSR[166.11].S "sp|Q8N6H7|ARFG2_HUMAN,tr|E9PIY6|E9PIY6_HUMAN,tr|E9PQP3|E9PQP3_HUMAN,tr|G5E9L0|G5E9L0_HUMAN,tr|A0A0D9SF70|A0A0D9SF70_HUMAN" 5 841.4719 0.76 12990 12302 2 841.471969 421.7432 ADP-ribosylation factor GTPase-activating protein 2 OS=Homo sapiens OX=9606 GN=ARFGAP2 PE=1 SV=1 9.75 2642.1 - 1.34E+06 - - - 0.0487 - 1.96 0.402 - 218 1 2 0 0 8 0 0 0 6.24E+07 8.18E+07 - - - 4.0397 0.9998 221125_WJC_METTL3_EV_vs_WT_F02.12303.12303.2 0.000892 22-Dec K.ILIANTGMDTDK.L "sp|P78371|TCPB_HUMAN,tr|F8VQ14|F8VQ14_HUMAN,tr|F5GWF6|F5GWF6_HUMAN" 3 1290.649 0.56 12991 12303 2 1290.648851 646.3318 T-complex protein 1 subunit beta OS=Homo sapiens OX=9606 GN=CCT2 PE=1 SV=4 4.21 2642.2 - 711513 - - - -0.079 - 2.066 0.431 - 280.3 1 2 0 -0.0001 12 0 0 0 3.24E+07 5.74E+07 - - - 4.1335 0.9701 221125_WJC_METTL3_EV_vs_WT_F02.12304.12304.2 0.018 18-Jun K.YMHSGPVVAM.V "sp|P15531|NDKA_HUMAN,tr|Q32Q12|Q32Q12_HUMAN,tr|J3KPD9|J3KPD9_HUMAN,tr|E5RHP0|E5RHP0_HUMAN,tr|E7ERL0|E7ERL0_HUMAN" 5 1090.494 - 12992 12304 2 1090.494742 546.2543 Nucleoside diphosphate kinase A OS=Homo sapiens OX=9606 GN=NME1 PE=1 SV=1 6.74 2642.3 - 702237 - - - 0.7061 - 1.524 0.398 - 122.2 1 1 0 0.0008 10 0 0 0 - - - - - 3.1565 0.9929 221125_WJC_METTL3_EV_vs_WT_F02.12305.12305.2 2.84 12-Aug K.TVPLLSK[136.11].V "sp|Q9H0H5|RGAP1_HUMAN,tr|H0YIK5|H0YIK5_HUMAN" 2 764.4887 0.02 12993 12305 2 764.488575 383.2516 Rac GTPase-activating protein 1 OS=Homo sapiens OX=9606 GN=RACGAP1 PE=1 SV=1 8.41 2642.5 - 702062 - - - -0.2171 - 1.477 0.078 - 289.1 1 2 0 -0.0002 7 0 0 0 4.98E+05 2.30E+07 - - - 0.8528 0.9984 221125_WJC_METTL3_EV_vs_WT_F02.12308.12308.2 0.28 14-Sep R.LVSLIGSK[136.11].T "sp|P25786|PSA1_HUMAN,tr|F5GX11|F5GX11_HUMAN" 2 823.5259 0.85 12994 12308 2 823.526408 412.7702 Proteasome subunit alpha type-1 OS=Homo sapiens OX=9606 GN=PSMA1 PE=1 SV=1 8.75 2642.9 - 3.01E+06 - - - 0.6727 - 1.658 0.207 - 192.5 1 2 0 0.0006 8 0 0 0 2.67E+08 3.13E+08 - - - 2.0946 0.9683 221125_WJC_METTL3_EV_vs_WT_F02.12309.12309.2 0.0025 12-Aug Q.WIC[160.03]C[160.03]DIR.Y sp|Q86U44|MTA70_HUMAN 1 1021.4474 0.02 12995 12309 2 1021.449159 511.731 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 5.82 2642.9 - 1.90E+06 - - - 1.7642 - 1.421 0.479 - 375.3 1 1 0 0.0018 7 0 0 0 7.96E+07 3.83E+09 - - - 3.6916 0.9192 221125_WJC_METTL3_EV_vs_WT_F02.12310.12310.2 0.539 18-Aug A.VQAAILMGDK[136.11].S "sp|P0DMV8|HS71A_HUMAN,sp|P34931|HS71L_HUMAN,sp|P0DMV9|HS71B_HUMAN,tr|Q53FA3|Q53FA3_HUMAN,tr|V9GZ37|V9GZ37_HUMAN,tr|A0A0G2JIW1|A0A0G2JIW1_HUMAN" 6 1052.578 0.27 12996 12310 2 1052.578488 527.2963 Heat shock 70 kDa protein 1A OS=Homo sapiens OX=9606 GN=HSPA1A PE=1 SV=1 5.81 2643 - 2.23E+06 - - - 0.4959 - 1.801 0.194 - 274 1 1 0 0.0005 10 0 0 0 2.01E+07 7.54E+07 - - - 2.116 0.9995 221125_WJC_METTL3_EV_vs_WT_F02.12314.12314.2 0.00872 18-Oct K.IVADFSASVK[136.11].K sp|P49915|GUAA_HUMAN 1 1043.5743 1.05 12998 12314 2 1043.57291 522.7944 GMP synthase [glutamine-hydrolyzing] OS=Homo sapiens OX=9606 GN=GMPS PE=1 SV=1 5.84 2643.4 - 1.11E+06 - - - -1.2946 - 1.71 0.386 - 199.1 1 2 0 -0.0014 10 0 0 0 3.29E+07 3.13E+07 - - - 3.3891 0.839 221125_WJC_METTL3_EV_vs_WT_F02.12319.12319.2 3.54 14-Jun R.IITSELYR[166.11].S "sp|Q13144|EI2BE_HUMAN,tr|A0A3B3ISX3|A0A3B3ISX3_HUMAN,tr|A0A3B3ITG6|A0A3B3ITG6_HUMAN,tr|A0A3B3IUF2|A0A3B3IUF2_HUMAN,tr|A0A3B3ITK8|A0A3B3ITK8_HUMAN,tr|A0A3B3ISS1|A0A3B3ISS1_HUMAN,tr|A0A3B3ISM8|A0A3B3ISM8_HUMAN,tr|A0A3B3ISV1|A0A3B3ISV1_HUMAN,tr|A0A3B3IUB1|A0A3B3IUB1_HUMAN,tr|A0A3B3ITQ2|A0A3B3ITQ2_HUMAN,tr|A0A3B3ISI2|A0A3B3ISI2_HUMAN,tr|A0A3B3IST9|A0A3B3IST9_HUMAN,tr|A0A3B3IRP4|A0A3B3IRP4_HUMAN,tr|A0A3B3IS56|A0A3B3IS56_HUMAN" 14 1003.5578 3.93 13001 12319 2 1003.55433 502.7862 Translation initiation factor eIF-2B subunit epsilon OS=Homo sapiens OX=9606 GN=EIF2B5 PE=1 SV=3 6 2644 - 592783 - - - -3.4238 - 1.251 0.023 - 85.5 1 2 0 -0.0034 8 0 0 0 7.84E+07 2.00E+07 - - - -0.1148 0.9944 221125_WJC_METTL3_EV_vs_WT_F02.12323.12323.2 0.0265 16-Jul K.ILASAPNWK.W sp|O00443|P3C2A_HUMAN 1 998.5549 2.49 13003 12323 2 998.552836 500.2847 Phosphatidylinositol 4-phosphate 3-kinase C2 domain-containing subunit alpha OS=Homo sapiens OX=9606 GN=PIK3C2A PE=1 SV=2 8.75 2644.6 - 1.49E+06 - - - -2.083 - 1.158 0.294 - 88.8 1 2 0 -0.0021 9 0 0 0 8.93E+07 3.59E+07 - - - 1.6362 0.9998 221125_WJC_METTL3_EV_vs_WT_F02.12326.12326.2 4.38E-05 20-Dec K.LVEALAAATEK[136.11].Q "sp|Q9BRJ7|TIRR_HUMAN,tr|K7EIN2|K7EIN2_HUMAN,tr|K7ENA3|K7ENA3_HUMAN" 3 1122.6376 21.94 13005 12326 2 1122.638646 562.3261 Tudor-interacting repair regulator protein OS=Homo sapiens OX=9606 GN=NUDT16L1 PE=1 SV=1 4.53 2644.9 - 480208 - - - 0.9406 - 2.294 0.443 - 390.6 1 2 0 0.0011 11 0 0 0 1.43E+09 6.51E+07 - - - 4.5588 0.9998 221125_WJC_METTL3_EV_vs_WT_F02.12327.12327.2 0.000121 16-Dec K.FDQLLAEEK[136.11].A "sp|Q7Z406|MYH14_HUMAN,sp|P35580|MYH10_HUMAN,sp|P35749|MYH11_HUMAN,sp|P35579|MYH9_HUMAN,tr|A1L2Z2|A1L2Z2_HUMAN,tr|A0A0C4DFM8|A0A0C4DFM8_HUMAN" 6 1099.5641 0.99 13006 12327 2 1099.56313 550.7893 Myosin-14 OS=Homo sapiens OX=9606 GN=MYH14 PE=1 SV=2 4.14 2645 - 1.20E+06 - - - -0.8731 - 2.173 0.375 - 419.6 1 2 0 -0.001 9 0 0 0 2.89E+08 2.90E+08 - - - 4.0558 0.9969 221125_WJC_METTL3_EV_vs_WT_F02.12328.12328.2 0.0264 14-Jul K.MIDMPVER[166.11].M "sp|Q15287|RNPS1_HUMAN,tr|H3BMM9|H3BMM9_HUMAN,tr|H3BV80|H3BV80_HUMAN,tr|H3BMS0|H3BMS0_HUMAN,tr|H3BTC0|H3BTC0_HUMAN,tr|H3BPG5|H3BPG5_HUMAN" 6 999.4757 1.27 13007 12328 2 999.47762 500.7451 RNA-binding protein with serine-rich domain 1 OS=Homo sapiens OX=9606 GN=RNPS1 PE=1 SV=1 4.37 2645.1 - 1.18E+06 - - - 1.928 - 1.372 0.282 - 145.1 1 2 0 0.0019 8 0 0 0 2.87E+08 2.26E+08 - - - 2.0771 0.9988 221125_WJC_METTL3_EV_vs_WT_F02.12329.12329.2 0.0168 14-Aug K.MIDMPVER.M "sp|Q15287|RNPS1_HUMAN,tr|H3BMM9|H3BMM9_HUMAN,tr|H3BV80|H3BV80_HUMAN,tr|H3BMS0|H3BMS0_HUMAN,tr|H3BTC0|H3BTC0_HUMAN,tr|H3BPG5|H3BPG5_HUMAN" 6 989.4674 1.27 13008 12329 2 989.46694 495.741 RNA-binding protein with serine-rich domain 1 OS=Homo sapiens OX=9606 GN=RNPS1 PE=1 SV=1 4.37 2645.2 - 703063 - - - -0.4881 - 1.591 0.244 - 251.1 1 2 0 -0.0005 8 0 0 0 2.87E+08 2.26E+08 - - - 2.2435 0.9973 221125_WJC_METTL3_EV_vs_WT_F02.12330.12330.2 0.0816 14-Jul K.TALDAFGR.L "sp|P51659|DHB4_HUMAN,tr|A0A804HK88|A0A804HK88_HUMAN,tr|A0A2R8YD50|A0A2R8YD50_HUMAN,tr|A0A804HKB5|A0A804HKB5_HUMAN,tr|E7ER27|E7ER27_HUMAN,tr|A0A2R8YF45|A0A2R8YF45_HUMAN,tr|E7EPL9|E7EPL9_HUMAN,tr|A0A804HKU2|A0A804HKU2_HUMAN,tr|A0A2R8YDT8|A0A2R8YDT8_HUMAN,tr|A0A804HK65|A0A804HK65_HUMAN" 10 849.4345 1.33 13009 12330 2 849.433988 425.7245 Peroxisomal multifunctional enzyme type 2 OS=Homo sapiens OX=9606 GN=HSD17B4 PE=1 SV=3 5.5 2645.3 - 604796 - - - -0.5639 - 1.203 0.271 - 169.7 1 2 0 -0.0005 8 0 0 0 1.24E+08 9.34E+07 - - - 1.5999 0.9963 221125_WJC_METTL3_EV_vs_WT_F02.12331.12331.2 0.523 20-Aug K.GALTLSSPEVR[166.11].F "sp|Q9Y2L1|RRP44_HUMAN,tr|G3V1J5|G3V1J5_HUMAN" 2 1138.6222 1.91 13010 12331 2 1138.622414 570.3184 Exosome complex exonuclease RRP44 OS=Homo sapiens OX=9606 GN=DIS3 PE=1 SV=2 6 2645.4 - 198058 - - - 0.2248 - 1.809 0.111 - 165.1 2 2 0 0.0003 11 0 0 0 3.70E+07 1.93E+07 - - - 1.3299 0.9716 221125_WJC_METTL3_EV_vs_WT_F02.12334.12334.2 0.327 12-Jun K.VLYDFNK.L "sp|O00566|MPP10_HUMAN,tr|U3KQ48|U3KQ48_HUMAN" 2 897.4596 0.97 13011 12334 2 897.45881 449.7371 U3 small nucleolar ribonucleoprotein protein MPP10 OS=Homo sapiens OX=9606 GN=MPHOSPH10 PE=1 SV=2 5.81 2645.8 - 6.13E+06 - - - -0.9014 - 0.876 0.189 - 88.6 1 2 0 -0.0008 7 0 0 0 2.04E+08 2.12E+08 - - - 0.0172 0.9994 221125_WJC_METTL3_EV_vs_WT_F02.12335.12335.2 0.00212 20-Nov K.GALTLSSPEVR.F "sp|Q9Y2L1|RRP44_HUMAN,tr|G3V1J5|G3V1J5_HUMAN" 2 1128.6139 1.9 13012 12335 2 1128.61109 565.3142 Exosome complex exonuclease RRP44 OS=Homo sapiens OX=9606 GN=DIS3 PE=1 SV=2 6 2646 - 658269 - - - -2.4791 - 2.364 0.356 - 384.9 1 2 0 -0.0028 11 0 0 0 3.70E+07 1.95E+07 - - - 3.997 0.9997 221125_WJC_METTL3_EV_vs_WT_F02.12337.12337.2 0.00742 16-Oct K.FDQLLAEEK.A "sp|Q7Z406|MYH14_HUMAN,sp|P35580|MYH10_HUMAN,sp|P35749|MYH11_HUMAN,sp|P35579|MYH9_HUMAN,tr|A1L2Z2|A1L2Z2_HUMAN,tr|A0A0C4DFM8|A0A0C4DFM8_HUMAN" 6 1091.5499 1.01 13014 12337 2 1091.548663 546.7822 Myosin-14 OS=Homo sapiens OX=9606 GN=MYH14 PE=1 SV=2 4.14 2646.1 - 1.62E+06 - - - -1.1241 - 2.087 0.378 - 307.2 1 2 0 -0.0012 9 0 0 0 2.94E+08 2.91E+08 - - - 3.961 0.9645 221125_WJC_METTL3_EV_vs_WT_F02.12338.12338.2 1.71 12-Jun K.ELITLAK[136.11].C "sp|P11172|UMPS_HUMAN,tr|E9PFD2|E9PFD2_HUMAN" 2 794.4993 4.13 13015 12338 2 794.499251 398.2569 Uridine 5'-monophosphate synthase OS=Homo sapiens OX=9606 GN=UMPS PE=1 SV=1 6.1 2646.2 - 868580 - - - -0.068 - 1.189 0.026 - 91.4 1 2 0 -0.0001 7 0 0 0 7.62E+07 1.84E+07 - - - -0.2185 0.9963 221125_WJC_METTL3_EV_vs_WT_F02.12343.12343.2 0.0946 16-Aug K.AIFTQETIK.E "sp|P82094|TMF1_HUMAN,tr|A0A2R8Y7M0|A0A2R8Y7M0_HUMAN" 2 1049.5757 1.42 13017 12343 2 1049.573168 525.7951 TATA element modulatory factor OS=Homo sapiens OX=9606 GN=TMF1 PE=1 SV=2 6.05 2646.8 - 1.57E+06 - - - -2.4229 - 1.511 0.261 - 191 1 2 0 -0.0025 9 0 0 0 3.52E+08 2.48E+08 - - - 2.1621 0.9982 221125_WJC_METTL3_EV_vs_WT_F02.12345.12345.2 2.75E-05 20-Aug K.VLLSDSNLHDA.- "sp|Q6FI81|CPIN1_HUMAN,tr|H3BV90|H3BV90_HUMAN" 2 1182.5881 - 13019 12345 2 1182.592178 592.3013 Anamorsin OS=Homo sapiens OX=9606 GN=CIAPIN1 PE=1 SV=2 4.2 2647 - 492205 - - - 3.4763 - 1.554 0.462 - 134.7 1 2 0 0.0041 11 0 0 0 - - - - - 3.6446 0.9923 221125_WJC_METTL3_EV_vs_WT_F02.12346.12346.2 0.319 14-Aug R.VQMLLSDR.F "sp|Q6P2Q9|PRP8_HUMAN,tr|I3L1T8|I3L1T8_HUMAN" 2 960.5063 0.56 13020 12346 2 960.505447 481.2604 Pre-mRNA-processing-splicing factor 8 OS=Homo sapiens OX=9606 GN=PRPF8 PE=1 SV=2 5.81 2647 - 6.57E+06 - - - -0.8371 - 1.435 0.102 - 184.7 1 2 0 -0.0008 8 0 0 0 3.45E+07 6.15E+07 - - - 0.8834 0.9994 221125_WJC_METTL3_EV_vs_WT_F02.12349.12349.2 0.0039 12-Jul K.VVFC[160.03]MDR[166.11].A "sp|Q99615|DNJC7_HUMAN,tr|A0A6I8PRZ0|A0A6I8PRZ0_HUMAN,tr|A0A6I8PLE7|A0A6I8PLE7_HUMAN,tr|A0A6I8PR89|A0A6I8PR89_HUMAN,tr|A0A6I8PIK4|A0A6I8PIK4_HUMAN,tr|A0A6I8PUC2|A0A6I8PUC2_HUMAN,tr|A0A6I8PS32|A0A6I8PS32_HUMAN,tr|K7EPP7|K7EPP7_HUMAN,tr|A0A6I8PUD4|A0A6I8PUD4_HUMAN,tr|K7EIH8|K7EIH8_HUMAN,tr|K7ER44|K7ER44_HUMAN,tr|A0A6I8PU73|A0A6I8PU73_HUMAN,tr|K7EK03|K7EK03_HUMAN,tr|K7EJV7|K7EJV7_HUMAN,tr|A0A6I8PU89|A0A6I8PU89_HUMAN" 15 935.4233 0.68 13021 12349 2 935.422495 468.7189 DnaJ homolog subfamily C member 7 OS=Homo sapiens OX=9606 GN=DNAJC7 PE=1 SV=2 5.8 2647.4 - 1.91E+06 - - - -0.8221 - 1.395 0.395 - 210.9 1 2 0 -0.0008 7 0 0 0 3.82E+07 5.60E+07 - - - 3.013 0.9998 221125_WJC_METTL3_EV_vs_WT_F02.12351.12351.2 0.000214 20-Sep K.VLFSSNGGVVK[136.11].G "sp|P26599|PTBP1_HUMAN,tr|A0A0U1RRM4|A0A0U1RRM4_HUMAN,tr|A6NLN1|A6NLN1_HUMAN,tr|A0A0D9SF20|A0A0D9SF20_HUMAN,tr|A0A7I2V621|A0A7I2V621_HUMAN" 5 1113.6274 0.95 13022 12351 2 1113.626603 557.821 Polypyrimidine tract-binding protein 1 OS=Homo sapiens OX=9606 GN=PTBP1 PE=1 SV=1 8.72 2647.6 - 1.25E+07 - - - -0.6789 - 1.71 0.502 - 185.5 1 2 0 -0.0008 11 0 0 0 2.26E+09 2.39E+09 - - - 4.1999 0.9996 221125_WJC_METTL3_EV_vs_WT_F02.12355.12355.2 0.00738 16-Jul K.DVDNAYMIK.V sp|P35908|K22E_HUMAN 1 1067.4957 125.26 13024 12355 2 1067.494057 534.7551 "Keratin, type II cytoskeletal 2 epidermal OS=Homo sapiens OX=9606 GN=KRT2 PE=1 SV=2" 4.21 2648.1 - 5.57E+06 - - - -1.5822 - 1.612 0.444 - 100 1 2 0 -0.0017 9 0 0 0 3.09E+09 2.46E+07 - - - 3.7012 0.9889 221125_WJC_METTL3_EV_vs_WT_F02.12356.12356.2 0.919 12-Jun R.NLVVIPK.S sp|P15121|ALDR_HUMAN 1 781.5062 0.95 13025 12356 2 781.505981 391.7604 Aldo-keto reductase family 1 member B1 OS=Homo sapiens OX=9606 GN=AKR1B1 PE=1 SV=3 8.75 2648.2 - 830649 - - - -0.2482 - 1.145 0.146 - 89 1 2 0 -0.0002 7 0 0 0 7.56E+07 7.93E+07 - - - 0.5483 0.9991 221125_WJC_METTL3_EV_vs_WT_F02.12357.12357.2 0.00454 16-Aug K.VSLEPLPAR.L sp|Q6ZU65|UBN2_HUMAN 1 980.5655 1.47 13026 12357 2 980.564681 491.29 Ubinuclein-2 OS=Homo sapiens OX=9606 GN=UBN2 PE=1 SV=2 5.97 2648.3 - 759556 - - - -0.8159 - 1.77 0.255 - 196.4 1 2 0 -0.0008 9 0 0 0 1.76E+08 1.20E+08 - - - 2.5761 0.9999 221125_WJC_METTL3_EV_vs_WT_F02.12359.12359.2 9.37E-07 22-Oct R.MVPAGMGAGLER.M "sp|P52272|HNRPM_HUMAN,tr|M0R2I7|M0R2I7_HUMAN,tr|A0A087X0X3|A0A087X0X3_HUMAN,tr|M0QZM1|M0QZM1_HUMAN" 4 1187.5791 1.58 13027 12359 2 1187.577943 594.7968 Heterogeneous nuclear ribonucleoprotein M OS=Homo sapiens OX=9606 GN=HNRNPM PE=1 SV=3 5.75 2648.5 - 1.21E+07 - - - -0.9734 - 1.923 0.594 - 367.5 1 2 0 -0.0012 12 0 0 0 1.13E+09 7.13E+08 - - - 5.1484 0.9979 221125_WJC_METTL3_EV_vs_WT_F02.12361.12361.2 0.101 12-Jul K.FFIDQSK[136.11].K "sp|Q12931|TRAP1_HUMAN,tr|I3L0K7|I3L0K7_HUMAN" 2 891.4582 0.39 13028 12361 2 891.458176 446.7364 "Heat shock protein 75 kDa, mitochondrial OS=Homo sapiens OX=9606 GN=TRAP1 PE=1 SV=3" 5.84 2648.7 - 1.64E+06 - - - 0.0079 - 1.211 0.285 - 109.2 1 2 0 0 7 0 0 0 2.06E+08 5.24E+08 - - - 1.7526 0.9886 221125_WJC_METTL3_EV_vs_WT_F02.12363.12363.2 1.61 12-Jul K.FLTLGSK.F "sp|Q9Y2J2|E41L3_HUMAN,sp|O43491|E41L2_HUMAN,tr|A0A1B0GTF8|A0A1B0GTF8_HUMAN,tr|A0A2R8Y5B3|A0A2R8Y5B3_HUMAN,tr|A0A0A0MRA8|A0A0A0MRA8_HUMAN,tr|E9PII3|E9PII3_HUMAN,tr|E9PHY5|E9PHY5_HUMAN,tr|E9PK52|E9PK52_HUMAN,tr|A8K968|A8K968_HUMAN,tr|J3KT37|J3KT37_HUMAN,tr|A0A0A0MSA4|A0A0A0MSA4_HUMAN" 11 764.4432 0.65 13030 12363 2 764.44162 383.2289 Band 4.1-like protein 3 OS=Homo sapiens OX=9606 GN=EPB41L3 PE=1 SV=2 8.75 2648.9 - 657887 - - - -2.1192 - 1.267 0.18 - 154.2 1 2 0 -0.0016 7 0 0 0 7.69E+07 1.18E+08 - - - 1.1198 0.9859 221125_WJC_METTL3_EV_vs_WT_F02.12366.12366.2 1.1 12-Jul K.LGLQSLR[166.11].N "sp|P18085|ARF4_HUMAN,tr|C9JAK5|C9JAK5_HUMAN,tr|U3KQF2|U3KQF2_HUMAN" 3 795.4842 0.78 13031 12366 2 795.482496 398.7494 ADP-ribosylation factor 4 OS=Homo sapiens OX=9606 GN=ARF4 PE=1 SV=3 9.75 2649.3 - 3.13E+06 - - - -2.1521 - 1.565 0.071 - 135.2 1 2 0 -0.0017 7 0 0 0 2.58E+08 3.31E+08 - - - 0.984 0.9996 221125_WJC_METTL3_EV_vs_WT_F02.12367.12367.2 0.0129 14-Sep K.MFEELGQR[166.11].L "sp|Q92598|HS105_HUMAN,tr|A0A0A0MSM0|A0A0A0MSM0_HUMAN" 2 1018.4781 0.12 13032 12367 2 1018.476713 510.2463 Heat shock protein 105 kDa OS=Homo sapiens OX=9606 GN=HSPH1 PE=1 SV=1 4.53 2649.3 - 3.57E+06 - - - -1.3972 - 1.667 0.419 - 406.5 1 2 0 -0.0014 8 0 0 0 8.06E+07 6.56E+08 - - - 3.6765 0.9834 221125_WJC_METTL3_EV_vs_WT_F02.12370.12370.2 1.24 16-May R.VITWTTEPK[136.11].S "sp|O75122|CLAP2_HUMAN,tr|E7ERI8|E7ERI8_HUMAN,tr|A0A804HJG7|A0A804HJG7_HUMAN,tr|J3KR49|J3KR49_HUMAN,tr|E7EW49|E7EW49_HUMAN,tr|E3W994|E3W994_HUMAN,tr|A0A0U1RQI6|A0A0U1RQI6_HUMAN,tr|H7C4I5|H7C4I5_HUMAN" 8 1081.5899 0.65 13033 12370 2 1081.588607 541.8022 CLIP-associating protein 2 OS=Homo sapiens OX=9606 GN=CLASP2 PE=1 SV=3 5.97 2649.7 - 328602 - - - -1.2056 - 1.095 0.175 - 59.4 2 2 0 -0.0013 9 0 0 0 8.91E+06 1.38E+07 - - - 0.4612 0.9871 221125_WJC_METTL3_EV_vs_WT_F02.12376.12376.2 1.26 12-Aug R.NLVVIPK[136.11].S sp|P15121|ALDR_HUMAN 1 789.5204 0.95 13035 12376 2 789.518834 395.7675 Aldo-keto reductase family 1 member B1 OS=Homo sapiens OX=9606 GN=AKR1B1 PE=1 SV=3 8.75 2650.5 - 2.83E+06 - - - -1.9518 - 1.366 0.124 - 225.6 1 2 0 -0.0015 7 0 0 0 7.56E+07 7.92E+07 - - - 0.9446 0.9971 221125_WJC_METTL3_EV_vs_WT_F02.12377.12377.2 0.0245 18-Aug R.VNGLTTVALK[136.11].E "sp|Q86YP4|P66A_HUMAN,tr|C9JJK9|C9JJK9_HUMAN,tr|C9JMI3|C9JMI3_HUMAN,tr|C9JGN4|C9JGN4_HUMAN" 4 1022.6215 1.87 13036 12377 2 1022.622942 512.318 Transcriptional repressor p66-alpha OS=Homo sapiens OX=9606 GN=GATAD2A PE=1 SV=1 8.72 2650.6 - 1.86E+06 - - - 1.3651 - 1.399 0.255 - 152.4 1 2 0 0.0014 10 0 0 0 2.20E+08 1.18E+08 - - - 1.8612 0.9983 221125_WJC_METTL3_EV_vs_WT_F02.12378.12378.2 0.0987 14-Jul K.LINAVELK[136.11].K sp|P56192|SYMC_HUMAN 1 906.563 1.06 13037 12378 2 906.562308 454.2888 "Methionine--tRNA ligase, cytoplasmic OS=Homo sapiens OX=9606 GN=MARS1 PE=1 SV=2" 6 2650.6 - 2.67E+06 - - - -0.728 - 1.354 0.278 - 98.7 1 2 0 -0.0007 8 0 0 0 8.76E+07 8.27E+07 - - - 2.0081 0.9986 221125_WJC_METTL3_EV_vs_WT_F02.12386.12386.2 0.197 12-Jul K.FFIDQSK.K "sp|Q12931|TRAP1_HUMAN,tr|I3L0K7|I3L0K7_HUMAN" 2 883.444 0.5 13041 12386 2 883.443586 442.7293 "Heat shock protein 75 kDa, mitochondrial OS=Homo sapiens OX=9606 GN=TRAP1 PE=1 SV=3" 5.84 2651.5 - 4.56E+06 - - - -0.4335 - 1.144 0.355 - 126.7 1 2 0 -0.0004 7 0 0 0 2.09E+08 4.22E+08 - - - 2.0892 1 221125_WJC_METTL3_EV_vs_WT_F02.12390.12390.2 3.58E-08 13/20 R.FDGGVEAIATR.Q sp|P33908|MA1A1_HUMAN 1 1134.5669 214.73 13043 12390 2 1134.569152 568.2907 "Mannosyl-oligosaccharide 1,2-alpha-mannosidase IA OS=Homo sapiens OX=9606 GN=MAN1A1 PE=1 SV=3" 4.37 2651.9 - 550021 - - - 1.9523 - 2.54 0.592 - 545 1 2 0 0.0022 11 0 0 0 2.86E+07 1.33E+05 - - - 5.9345 0.9994 221125_WJC_METTL3_EV_vs_WT_F02.12392.12392.3 0.00647 13/40 R.LLASTLVHSVK.K "sp|Q9NYF8|BCLF1_HUMAN,tr|E9PKI6|E9PKI6_HUMAN,tr|A0A1W2PQ43|A0A1W2PQ43_HUMAN,tr|E9PK91|E9PK91_HUMAN,tr|E9PJA7|E9PJA7_HUMAN,tr|E9PK09|E9PK09_HUMAN,tr|E9PQN2|E9PQN2_HUMAN" 7 1166.7023 2 13044 12392 3 1166.700721 389.908 Bcl-2-associated transcription factor 1 OS=Homo sapiens OX=9606 GN=BCLAF1 PE=1 SV=2 8.76 2652.1 - 2.68E+06 - - - -1.3611 - 2.358 0.259 - 142.4 1 2 0 -0.0016 11 0 0 0 2.23E+08 1.12E+08 - - - 3.8641 0.9989 221125_WJC_METTL3_EV_vs_WT_F02.12393.12393.2 0.00215 14-Aug K.MFEELGQR.L "sp|Q92598|HS105_HUMAN,tr|A0A0A0MSM0|A0A0A0MSM0_HUMAN" 2 1008.4699 0.12 13045 12393 2 1008.467271 505.2422 Heat shock protein 105 kDa OS=Homo sapiens OX=9606 GN=HSPH1 PE=1 SV=1 4.53 2652.2 - 1.25E+06 - - - -2.5732 - 1.598 0.406 - 279.4 1 2 0 -0.0026 8 0 0 0 8.06E+07 6.56E+08 - - - 3.4526 0.9991 221125_WJC_METTL3_EV_vs_WT_F02.12398.12398.2 0.000484 18-Aug R.FIGATANFSR.F "sp|Q8TDP1|RNH2C_HUMAN,tr|E9PN81|E9PN81_HUMAN" 2 1082.5509 0.26 13047 12398 2 1082.548274 542.2827 Ribonuclease H2 subunit C OS=Homo sapiens OX=9606 GN=RNASEH2C PE=1 SV=1 9.75 2652.8 - 437219 - - - -2.4193 - 1.603 0.424 - 154.1 1 2 0 -0.0026 10 0 0 0 4.11E+07 1.58E+08 - - - 3.489 0.9718 221125_WJC_METTL3_EV_vs_WT_F02.12404.12404.2 0.0522 14-Jun K.TALDAFGR[166.11].L "sp|P51659|DHB4_HUMAN,tr|A0A804HK88|A0A804HK88_HUMAN,tr|A0A2R8YD50|A0A2R8YD50_HUMAN,tr|A0A804HKB5|A0A804HKB5_HUMAN,tr|E7ER27|E7ER27_HUMAN,tr|A0A2R8YF45|A0A2R8YF45_HUMAN,tr|E7EPL9|E7EPL9_HUMAN,tr|A0A804HKU2|A0A804HKU2_HUMAN,tr|A0A2R8YDT8|A0A2R8YDT8_HUMAN,tr|A0A804HK65|A0A804HK65_HUMAN" 10 859.4427 1.32 13050 12404 2 859.438031 430.7286 Peroxisomal multifunctional enzyme type 2 OS=Homo sapiens OX=9606 GN=HSD17B4 PE=1 SV=3 5.5 2653.6 - 2.00E+06 - - - -5.4756 - 1.474 0.284 - 121.9 1 2 0 -0.0047 8 0 0 0 1.23E+08 9.34E+07 - - - 2.3073 0.9991 221125_WJC_METTL3_EV_vs_WT_F02.12405.12405.2 0.0663 16-Oct K.GVQTLVIGR[166.11].G "sp|Q9H7C9|AAMDC_HUMAN,tr|K4DI89|K4DI89_HUMAN,tr|E9PLK9|E9PLK9_HUMAN,tr|E9PNP3|E9PNP3_HUMAN,tr|E9PR47|E9PR47_HUMAN,tr|E9PJP1|E9PJP1_HUMAN" 6 951.5741 1.45 13051 12405 2 951.572998 476.7943 Mth938 domain-containing protein OS=Homo sapiens OX=9606 GN=AAMDC PE=1 SV=1 9.75 2653.7 - 905620 - - - -1.1423 - 1.805 0.263 - 372.7 1 2 0 -0.0011 9 0 0 0 6.42E+08 4.42E+08 - - - 2.6917 0.9988 221125_WJC_METTL3_EV_vs_WT_F02.12408.12408.2 0.0241 20-Oct R.LLASTLVHSVK[136.11].K "sp|Q9NYF8|BCLF1_HUMAN,tr|E9PKI6|E9PKI6_HUMAN,tr|A0A1W2PQ43|A0A1W2PQ43_HUMAN,tr|E9PK91|E9PK91_HUMAN,tr|E9PJA7|E9PJA7_HUMAN,tr|E9PK09|E9PK09_HUMAN,tr|E9PQN2|E9PQN2_HUMAN" 7 1174.7165 2.04 13052 12408 2 1174.713721 588.3655 Bcl-2-associated transcription factor 1 OS=Homo sapiens OX=9606 GN=BCLAF1 PE=1 SV=2 8.76 2654.1 - 875827 - - - -2.3733 - 1.841 0.341 - 176 1 2 0 -0.0028 11 0 0 0 7.25E+07 3.56E+07 - - - 3.2098 0.9985 221125_WJC_METTL3_EV_vs_WT_F02.12410.12410.2 0.0281 14-Jun K.GDPVAILK.R "sp|Q9P2E9|RRBP1_HUMAN,tr|A0A087WVV2|A0A087WVV2_HUMAN,tr|F8W7S5|F8W7S5_HUMAN" 3 811.4804 1.4 13053 12410 2 811.479581 406.7475 Ribosome-binding protein 1 OS=Homo sapiens OX=9606 GN=RRBP1 PE=1 SV=5 5.84 2654.3 - 1.50E+06 - - - -0.9526 - 1.275 0.323 - 134.7 1 2 0 -0.0008 8 0 0 0 1.72E+08 1.23E+08 - - - 2.1591 0.9847 221125_WJC_METTL3_EV_vs_WT_F02.12413.12413.2 0.117 14-Jul K.ILGLAPSR.A "sp|Q9UM00|TMCO1_HUMAN,tr|J3QQY2|J3QQY2_HUMAN" 2 825.5072 0.53 13056 12413 2 825.505832 413.7609 Calcium load-activated calcium channel OS=Homo sapiens OX=9606 GN=TMCO1 PE=1 SV=2 9.75 2654.5 - 1.03E+06 - - - -1.7032 - 1.59 0.055 - 85.8 2 2 0 -0.0014 8 0 0 0 3.29E+07 6.24E+07 - - - 0.7109 0.9999 221125_WJC_METTL3_EV_vs_WT_F02.12416.12416.2 1.58E-05 22-Oct R.MVPAGMGAGLER[166.11].M "sp|P52272|HNRPM_HUMAN,tr|M0R2I7|M0R2I7_HUMAN,tr|A0A087X0X3|A0A087X0X3_HUMAN,tr|M0QZM1|M0QZM1_HUMAN" 4 1197.5874 1.66 13057 12416 2 1197.586905 599.801 Heterogeneous nuclear ribonucleoprotein M OS=Homo sapiens OX=9606 GN=HNRNPM PE=1 SV=3 5.75 2654.9 - 5.52E+06 - - - -0.3874 - 1.899 0.626 - 365.1 1 2 0 -0.0005 12 0 0 0 9.84E+08 5.93E+08 - - - 5.3519 0.994 221125_WJC_METTL3_EV_vs_WT_F02.12422.12422.2 0.106 16-Jul K.VSLEPLPAR[166.11].L sp|Q6ZU65|UBN2_HUMAN 1 990.5738 1.48 13060 12422 2 990.572727 496.2942 Ubinuclein-2 OS=Homo sapiens OX=9606 GN=UBN2 PE=1 SV=2 5.97 2655.7 - 2.47E+06 - - - -1.0337 - 1.226 0.201 - 144.4 1 2 0 -0.001 9 0 0 0 1.77E+08 1.20E+08 - - - 1.1147 0.9997 221125_WJC_METTL3_EV_vs_WT_F02.12425.12425.2 2.63E-05 16-Nov K.GVQTLVIGR.G "sp|Q9H7C9|AAMDC_HUMAN,tr|K4DI89|K4DI89_HUMAN,tr|E9PLK9|E9PLK9_HUMAN,tr|E9PNP3|E9PNP3_HUMAN,tr|E9PR47|E9PR47_HUMAN,tr|E9PJP1|E9PJP1_HUMAN" 6 941.5658 1.45 13061 12425 2 941.565065 471.7902 Mth938 domain-containing protein OS=Homo sapiens OX=9606 GN=AAMDC PE=1 SV=1 9.75 2656.1 - 5.39E+06 - - - -0.7965 - 2.257 0.316 - 529.4 1 2 0 -0.0008 9 0 0 0 6.43E+08 4.42E+08 - - - 3.7298 0.9572 221125_WJC_METTL3_EV_vs_WT_F02.12427.12427.2 10.3 14-Jun K.LYLPVQNK.A sp|Q9Y6A4|CFA20_HUMAN 1 973.5597 0.3 13063 12427 2 973.558663 487.7871 Cilia- and flagella-associated protein 20 OS=Homo sapiens OX=9606 GN=CFAP20 PE=1 SV=1 8.59 2656.2 - 1.85E+06 - - - -1.0313 - 1.213 0.022 - 109.7 1 2 0 -0.001 8 0 0 0 4.68E+07 1.57E+08 - - - -0.2145 0.9988 221125_WJC_METTL3_EV_vs_WT_F02.12430.12430.2 1.02 14-Aug R.IEEFVYEK.L "sp|Q9Y371|SHLB1_HUMAN,tr|A0A087WW40|A0A087WW40_HUMAN" 2 1055.5175 1.14 13064 12430 2 1055.517023 528.766 Endophilin-B1 OS=Homo sapiens OX=9606 GN=SH3GLB1 PE=1 SV=1 4.25 2656.6 - 2.98E+06 - - - -0.4784 - 1.637 0.23 - 162.5 1 2 0 -0.0005 8 0 0 0 1.21E+08 1.07E+08 - - - 2.2261 0.9992 221125_WJC_METTL3_EV_vs_WT_F02.12431.12431.2 0.049 20-Sep R.LLASTLVHSVK.K "sp|Q9NYF8|BCLF1_HUMAN,tr|E9PKI6|E9PKI6_HUMAN,tr|A0A1W2PQ43|A0A1W2PQ43_HUMAN,tr|E9PK91|E9PK91_HUMAN,tr|E9PJA7|E9PJA7_HUMAN,tr|E9PK09|E9PK09_HUMAN,tr|E9PQN2|E9PQN2_HUMAN" 7 1166.7023 2.04 13065 12431 2 1166.70112 584.3584 Bcl-2-associated transcription factor 1 OS=Homo sapiens OX=9606 GN=BCLAF1 PE=1 SV=2 8.76 2656.7 - 2.29E+06 - - - -1.0191 - 1.918 0.262 - 181.4 1 2 0 -0.0012 11 0 0 0 7.25E+07 3.56E+07 - - - 2.7376 0.9997 221125_WJC_METTL3_EV_vs_WT_F02.12437.12437.2 0.0016 14-Sep R.LLGQIVDR.C sp|Q96I24|FUBP3_HUMAN 1 912.5393 1.65 13069 12437 2 912.538976 457.2769 Far upstream element-binding protein 3 OS=Homo sapiens OX=9606 GN=FUBP3 PE=1 SV=2 5.84 2657.3 - 1.06E+08 - - - -0.3178 - 1.936 0.348 - 256.5 1 2 0 -0.0003 8 0 0 0 3.67E+09 2.23E+09 - - - 3.6036 0.9894 221125_WJC_METTL3_EV_vs_WT_F02.12438.12438.2 0.632 14-Jul K.ALYTLVNK[136.11].V "sp|Q92552|RT27_HUMAN,tr|G5EA06|G5EA06_HUMAN,tr|D6RH20|D6RH20_HUMAN,tr|D6RJC7|D6RJC7_HUMAN" 4 928.5473 40.27 13070 12438 2 928.550031 465.2809 "28S ribosomal protein S27, mitochondrial OS=Homo sapiens OX=9606 GN=MRPS27 PE=1 SV=3" 8.63 2657.4 - 1.80E+06 - - - 2.9218 - 1.423 0.207 - 159 1 2 0 0.0027 8 0 0 0 1.98E+09 4.93E+07 - - - 1.633 0.9999 221125_WJC_METTL3_EV_vs_WT_F02.12440.12440.2 6.83E-05 22-Aug R.ILVAGDSMDSVK.Q sp|O95782|AP2A1_HUMAN 1 1233.6275 0.83 13072 12440 2 1233.626353 617.821 AP-2 complex subunit alpha-1 OS=Homo sapiens OX=9606 GN=AP2A1 PE=1 SV=3 4.21 2657.6 - 189516 - - - -0.9209 - 1.883 0.547 - 150.7 1 2 0 -0.0011 12 0 0 0 8.84E+06 1.06E+07 - - - 4.746 0.9651 221125_WJC_METTL3_EV_vs_WT_F02.12443.12443.2 0.126 16-Nov R.LEELGLAGR[166.11].C "sp|Q9UBN7|HDAC6_HUMAN,tr|A0A2R8YDE6|A0A2R8YDE6_HUMAN" 2 966.5374 1.16 13073 12443 2 966.543658 484.276 Histone deacetylase 6 OS=Homo sapiens OX=9606 GN=HDAC6 PE=1 SV=2 4.53 2658 - 1.56E+06 - - - 6.5109 - 2.175 0.195 - 426.8 1 2 0 0.0063 9 0 0 0 1.68E+08 1.46E+08 - - - 2.7273 0.9994 221125_WJC_METTL3_EV_vs_WT_F02.12444.12444.2 0.142 16-Sep R.LEELGLAGR.C "sp|Q9UBN7|HDAC6_HUMAN,tr|A0A2R8YDE6|A0A2R8YDE6_HUMAN" 2 956.5291 1 13074 12444 2 956.529009 479.2718 Histone deacetylase 6 OS=Homo sapiens OX=9606 GN=HDAC6 PE=1 SV=2 4.53 2658.1 - 1.11E+06 - - - -0.0899 - 1.917 0.253 - 254.8 1 2 0 -0.0001 9 0 0 0 1.64E+08 1.64E+08 - - - 2.7923 0.9998 221125_WJC_METTL3_EV_vs_WT_F02.12446.12446.2 3.59E-06 22-Nov R.ILVAGDSMDSVK[136.11].Q sp|O95782|AP2A1_HUMAN 1 1241.6417 0.83 13076 12446 2 1241.643819 621.8281 AP-2 complex subunit alpha-1 OS=Homo sapiens OX=9606 GN=AP2A1 PE=1 SV=3 4.21 2658.3 - 353365 - - - 1.7155 - 2.317 0.504 - 375.3 1 2 0 0.0021 12 0 0 0 8.84E+06 1.06E+07 - - - 4.9738 0.9657 221125_WJC_METTL3_EV_vs_WT_F02.12449.12449.2 0.000874 20-Jun R.MLPHAPGVQMQ.A "sp|Q92769|HDAC2_HUMAN,sp|Q13547|HDAC1_HUMAN" 2 1207.5842 - 13078 12449 2 1207.584819 604.7994 Histone deacetylase 2 OS=Homo sapiens OX=9606 GN=HDAC2 PE=1 SV=2 6.49 2658.7 - 433242 - - - 0.5258 - 1.531 0.373 - 90.3 1 1 0 0.0006 11 0 0 0 - - - - - 2.948 0.9993 221125_WJC_METTL3_EV_vs_WT_F02.12457.12457.2 0.00108 14-Sep R.ILLC[160.03]ENYR.S "sp|P42694|HELZ_HUMAN,tr|J3QS41|J3QS41_HUMAN" 2 1079.5434 0.48 13084 12457 2 1079.542695 540.779 Probable helicase with zinc finger domain OS=Homo sapiens OX=9606 GN=HELZ PE=1 SV=2 5.99 2659.6 - 1.17E+06 - - - -0.6206 - 1.984 0.218 - 272.5 1 2 0 -0.0007 8 0 0 0 7.58E+07 1.57E+08 - - - 2.7172 0.9639 221125_WJC_METTL3_EV_vs_WT_F02.12461.12461.2 1.64 12-Jun K.DVNSLLK.Y sp|Q9P032|NDUF4_HUMAN 1 787.444 1.33 13086 12461 2 787.443762 394.7293 NADH dehydrogenase [ubiquinone] 1 alpha subcomplex assembly factor 4 OS=Homo sapiens OX=9606 GN=NDUFAF4 PE=1 SV=1 5.84 2660 - 2.69E+06 - - - -0.2629 - 1.124 0.049 - 118.7 1 2 0 -0.0002 7 0 0 0 1.56E+08 1.17E+08 - - - -0.2268 0.9773 221125_WJC_METTL3_EV_vs_WT_F02.12462.12462.2 0.373 12-Jun K.DVNSLLK[136.11].Y sp|Q9P032|NDUF4_HUMAN 1 795.4582 1.38 13087 12462 2 795.457731 398.7364 NADH dehydrogenase [ubiquinone] 1 alpha subcomplex assembly factor 4 OS=Homo sapiens OX=9606 GN=NDUFAF4 PE=1 SV=1 5.84 2660.1 - 2.19E+06 - - - -0.5506 - 1.124 0.093 - 119.4 1 2 0 -0.0004 7 0 0 0 1.62E+08 1.17E+08 - - - 0.0981 0.9999 221125_WJC_METTL3_EV_vs_WT_F02.12463.12463.2 1.83E-07 20-Nov K.LSAMMGAVAEK[136.11].K "sp|Q86U44|MTA70_HUMAN,tr|F5H6D8|F5H6D8_HUMAN,tr|H0YFV6|H0YFV6_HUMAN,tr|B4DTN4|B4DTN4_HUMAN" 4 1114.5606 0.01 13088 12463 2 1114.560688 558.2876 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 6 2660.1 - 7.89E+06 - - - 0.0772 - 2.147 0.563 - 313.4 1 2 0 0.0001 11 0 0 0 1.30E+07 9.12E+08 - - - 5.2663 0.9995 221125_WJC_METTL3_EV_vs_WT_F02.12464.12464.2 0.00901 16-Aug K.IVNTPEVIR.V sp|Q9NZN3|EHD3_HUMAN 1 1039.6026 2.25 13089 12464 2 1039.602625 520.8086 EH domain-containing protein 3 OS=Homo sapiens OX=9606 GN=EHD3 PE=1 SV=2 6 2660.2 - 2.24E+06 - - - 0.0289 - 1.523 0.376 - 204.6 1 2 0 0 9 0 0 0 1.83E+08 8.12E+07 - - - 3.0352 0.9996 221125_WJC_METTL3_EV_vs_WT_F02.12465.12465.2 0.00514 14-Sep K.FGNIC[160.03]VVR[166.11].L sp|Q15393|SF3B3_HUMAN 1 973.5043 1.06 13090 12465 2 973.503175 487.7594 Splicing factor 3B subunit 3 OS=Homo sapiens OX=9606 GN=SF3B3 PE=1 SV=4 8.25 2660.2 - 1.43E+06 - - - -1.1464 - 1.659 0.4 - 279.6 1 2 0 -0.0011 8 0 0 0 7.10E+07 6.71E+07 - - - 3.5218 0.9923 221125_WJC_METTL3_EV_vs_WT_F02.12466.12466.2 1.34E-07 22-Nov E.MVGSMVGVYNGK[136.11].T "sp|P62841|RS15_HUMAN,tr|K7EJ78|K7EJ78_HUMAN,tr|K7EM56|K7EM56_HUMAN,tr|A0A0B4J2B4|A0A0B4J2B4_HUMAN,tr|S4R456|S4R456_HUMAN,tr|K7ELC2|K7ELC2_HUMAN,tr|K7EQJ5|K7EQJ5_HUMAN,tr|S4R417|S4R417_HUMAN" 8 1248.6086 0.94 13091 12466 2 1248.609838 625.3116 40S ribosomal protein S15 OS=Homo sapiens OX=9606 GN=RPS15 PE=1 SV=2 8.34 2660.3 - 204998 - - - 0.9795 - 2.167 0.565 - 295.2 1 1 0 0.0012 12 0 0 0 2.70E+07 2.87E+07 - - - 5.2485 0.9991 221125_WJC_METTL3_EV_vs_WT_F02.12468.12468.2 0.292 14-Sep R.LLGQIVDR[166.11].C sp|Q96I24|FUBP3_HUMAN 1 922.5475 1.65 13092 12468 2 922.547035 462.281 Far upstream element-binding protein 3 OS=Homo sapiens OX=9606 GN=FUBP3 PE=1 SV=2 5.84 2660.6 - 3.58E+07 - - - -0.5431 - 1.778 0.229 - 260.5 1 2 0 -0.0005 8 0 0 0 3.67E+09 2.23E+09 - - - 2.4679 0.9968 221125_WJC_METTL3_EV_vs_WT_F02.12470.12470.2 0.37 14-Aug K.IQSIYLER[166.11].F sp|Q9Y5J1|UTP18_HUMAN 1 1030.5687 2.7 13093 12470 2 1030.570175 516.2916 U3 small nucleolar RNA-associated protein 18 homolog OS=Homo sapiens OX=9606 GN=UTP18 PE=1 SV=3 6 2660.8 - 1.73E+06 - - - 1.4652 - 1.585 0.188 - 188 1 2 0 0.0015 8 0 0 0 9.65E+07 3.58E+07 - - - 1.8182 0.9952 221125_WJC_METTL3_EV_vs_WT_F02.12471.12471.2 0.402 16-Aug K.AVGPASILK[136.11].E sp|O95218|ZRAB2_HUMAN 1 862.5368 0.43 13094 12471 2 862.537738 432.2757 Zinc finger Ran-binding domain-containing protein 2 OS=Homo sapiens OX=9606 GN=ZRANB2 PE=1 SV=2 8.8 2660.9 - 501485 - - - 1.142 - 1.464 0.186 - 123.9 2 2 0 0.001 9 0 0 0 1.64E+07 3.77E+07 - - - 1.3828 0.9997 221125_WJC_METTL3_EV_vs_WT_F02.12472.12472.2 9.19E-05 18-Oct R.AGGFASALER[166.11].H "sp|Q9Y2Q9|RT28_HUMAN,tr|E5RFT8|E5RFT8_HUMAN,tr|H7C5V3|H7C5V3_HUMAN" 3 987.5013 1.08 13095 12472 2 987.501849 494.7579 "28S ribosomal protein S28, mitochondrial OS=Homo sapiens OX=9606 GN=MRPS28 PE=1 SV=1" 6.05 2661 - 1.38E+06 - - - 0.5418 - 1.876 0.39 - 370.5 1 2 0 0.0005 10 0 0 0 3.73E+07 3.44E+07 - - - 3.6775 0.9975 221125_WJC_METTL3_EV_vs_WT_F02.12473.12473.2 0.0831 16-Sep K.IVNTPEVIR[166.11].V sp|Q9NZN3|EHD3_HUMAN 1 1049.6109 2.34 13096 12473 2 1049.61214 525.8127 EH domain-containing protein 3 OS=Homo sapiens OX=9606 GN=EHD3 PE=1 SV=2 6 2661 - 1.05E+06 - - - 1.2147 - 1.559 0.218 - 190 1 2 0 0.0013 9 0 0 0 1.79E+08 7.66E+07 - - - 1.9354 0.9922 221125_WJC_METTL3_EV_vs_WT_F02.12474.12474.2 1.48E-05 22-Dec E.MVGSMVGVYNGK.T "sp|P62841|RS15_HUMAN,tr|K7EJ78|K7EJ78_HUMAN,tr|K7EM56|K7EM56_HUMAN,tr|A0A0B4J2B4|A0A0B4J2B4_HUMAN,tr|S4R456|S4R456_HUMAN,tr|K7ELC2|K7ELC2_HUMAN,tr|K7EQJ5|K7EQJ5_HUMAN,tr|S4R417|S4R417_HUMAN" 8 1240.5944 0.94 13097 12474 2 1240.595635 621.3045 40S ribosomal protein S15 OS=Homo sapiens OX=9606 GN=RPS15 PE=1 SV=2 8.34 2661.2 - 596542 - - - 0.9834 - 2.075 0.578 - 337.7 1 1 0 0.0012 12 0 0 0 2.70E+07 2.88E+07 - - - 5.2304 0.9262 221125_WJC_METTL3_EV_vs_WT_F02.12482.12482.2 4.06 12-Jun K.TIALNLK.K "sp|P32780|TF2H1_HUMAN,sp|A0AVF1|IFT56_HUMAN,tr|E9PM51|E9PM51_HUMAN,tr|Q96CU4|Q96CU4_HUMAN" 4 771.4854 0.15 13102 12482 2 771.485769 386.75 General transcription factor IIH subunit 1 OS=Homo sapiens OX=9606 GN=GTF2H1 PE=1 SV=1 8.41 2662.1 - 354907 - - - 0.4265 - 0.997 0.043 - 106.4 1 2 0 0.0003 7 0 0 0 1.08E+07 7.23E+07 - - - -0.651 0.9538 221125_WJC_METTL3_EV_vs_WT_F02.12487.12487.2 0.00569 14-Aug Y.TIMFGPDK.C "sp|P27824|CALX_HUMAN,tr|A0A7P0T937|A0A7P0T937_HUMAN,tr|A0A7P0T840|A0A7P0T840_HUMAN,tr|D6RFL1|D6RFL1_HUMAN,tr|A0A7P0Z4H2|A0A7P0Z4H2_HUMAN,tr|A0A7P0TB65|A0A7P0TB65_HUMAN,tr|A0A7P0TAE9|A0A7P0TAE9_HUMAN,tr|D6RGY2|D6RGY2_HUMAN,tr|A0A7P0T8G1|A0A7P0T8G1_HUMAN,tr|A0A7P0Z4D6|A0A7P0Z4D6_HUMAN,tr|A0A7P0Z484|A0A7P0Z484_HUMAN,tr|A0A7P0TAR9|A0A7P0TAR9_HUMAN,tr|A0A7P0T9L0|A0A7P0T9L0_HUMAN" 13 907.4473 1.12 13105 12487 2 907.447519 454.7309 Calnexin OS=Homo sapiens OX=9606 GN=CANX PE=1 SV=2 5.5 2662.7 - 4.43E+06 - - - 0.1973 - 1.393 0.344 - 204.6 1 1 0 0.0002 8 0 0 0 2.17E+08 1.95E+08 - - - 2.5814 0.992 221125_WJC_METTL3_EV_vs_WT_F02.12488.12488.2 0.698 14-Jul K.MYSEIDIK.V sp|Q15029|U5S1_HUMAN 1 997.479 1.47 13106 12488 2 997.478569 499.7468 116 kDa U5 small nuclear ribonucleoprotein component OS=Homo sapiens OX=9606 GN=EFTUD2 PE=1 SV=1 4.37 2662.8 - 3.96E+06 - - - -0.4662 - 1.369 0.108 - 188.1 1 2 0 -0.0005 8 0 0 0 1.38E+08 9.38E+07 - - - 0.7858 0.9996 221125_WJC_METTL3_EV_vs_WT_F02.12490.12490.2 0.000768 18-Nov R.AGGFASALER.H "sp|Q9Y2Q9|RT28_HUMAN,tr|E5RFT8|E5RFT8_HUMAN,tr|H7C5V3|H7C5V3_HUMAN" 3 977.493 1.08 13108 12490 2 977.49491 489.7538 "28S ribosomal protein S28, mitochondrial OS=Homo sapiens OX=9606 GN=MRPS28 PE=1 SV=1" 6.05 2662.9 - 1.82E+06 - - - 1.909 - 2.136 0.414 - 360 1 2 0 0.0019 10 0 0 0 3.72E+07 3.44E+07 - - - 4.2166 0.9996 221125_WJC_METTL3_EV_vs_WT_F02.12492.12492.2 0.000294 18-Jul K.YNPGYVLASR.L "sp|Q8IZH2|XRN1_HUMAN,tr|H7C5E4|H7C5E4_HUMAN" 2 1138.5771 1.55 13110 12492 2 1138.576606 570.2958 5'-3' exoribonuclease 1 OS=Homo sapiens OX=9606 GN=XRN1 PE=1 SV=1 8.59 2663.2 - 267482 - - - -0.4409 - 1.535 0.419 - 148.2 1 2 0 -0.0005 10 0 0 0 4.64E+07 3.00E+07 - - - 3.3317 0.9948 221125_WJC_METTL3_EV_vs_WT_F02.12496.12496.2 0.0372 14-Jul K.TIGVDFAK.S sp|P52756|RBM5_HUMAN 1 849.4596 1.03 13112 12496 2 849.459738 425.7371 RNA-binding protein 5 OS=Homo sapiens OX=9606 GN=RBM5 PE=1 SV=2 5.5 2663.6 - 2.33E+06 - - - 0.1401 - 0.966 0.291 - 117.2 1 2 0 0.0001 8 0 0 0 9.04E+07 8.79E+07 - - - 1.086 0.9724 221125_WJC_METTL3_EV_vs_WT_F02.12505.12505.2 0.00885 14-Jul Y.TIMFGPDK[136.11].C "sp|P27824|CALX_HUMAN,tr|A0A7P0T937|A0A7P0T937_HUMAN,tr|A0A7P0T840|A0A7P0T840_HUMAN,tr|D6RFL1|D6RFL1_HUMAN,tr|A0A7P0Z4H2|A0A7P0Z4H2_HUMAN,tr|A0A7P0TB65|A0A7P0TB65_HUMAN,tr|A0A7P0TAE9|A0A7P0TAE9_HUMAN,tr|D6RGY2|D6RGY2_HUMAN,tr|A0A7P0T8G1|A0A7P0T8G1_HUMAN,tr|A0A7P0Z4D6|A0A7P0Z4D6_HUMAN,tr|A0A7P0Z484|A0A7P0Z484_HUMAN,tr|A0A7P0TAR9|A0A7P0TAR9_HUMAN,tr|A0A7P0T9L0|A0A7P0T9L0_HUMAN" 13 915.4615 1.14 13119 12505 2 915.460785 458.738 Calnexin OS=Homo sapiens OX=9606 GN=CANX PE=1 SV=2 5.5 2664.6 - 5.62E+06 - - - -0.8247 - 1.371 0.434 - 158.8 1 1 0 -0.0008 8 0 0 0 2.22E+08 1.95E+08 - - - 3.1979 0.9997 221125_WJC_METTL3_EV_vs_WT_F02.12506.12506.2 0.000589 16-Aug K.ESPLLNDYR.G "sp|A6ZKI3|RTL8C_HUMAN,sp|Q9BWD3|RTL8A_HUMAN" 2 1105.5404 0.38 13120 12506 2 1105.540471 553.7775 Retrotransposon Gag-like protein 8C OS=Homo sapiens OX=9606 GN=RTL8C PE=1 SV=1 4.37 2664.7 - 878502 - - - 0.0751 - 1.594 0.445 - 278.9 1 2 0 0.0001 9 0 0 0 3.74E+07 9.91E+07 - - - 3.6766 0.9994 221125_WJC_METTL3_EV_vs_WT_F02.12508.12508.2 0.0567 18-Sep K.LITPAVVSER[166.11].L sp|P62851|RS25_HUMAN 1 1093.6371 1.19 13122 12508 2 1093.638899 547.8258 40S ribosomal protein S25 OS=Homo sapiens OX=9606 GN=RPS25 PE=1 SV=1 6 2664.9 - 765288 - - - 1.6642 - 2.079 0.33 - 308.9 1 2 0 0.0018 10 0 0 0 2.80E+09 2.34E+09 - - - 3.5207 0.9968 221125_WJC_METTL3_EV_vs_WT_F02.12510.12510.2 0.584 14-Jul R.IGYYEIDR.T "sp|Q9Y2K2|SIK3_HUMAN,tr|H0Y4E8|H0Y4E8_HUMAN,tr|H7C038|H7C038_HUMAN" 3 1027.4975 14.49 13124 12510 2 1027.498592 514.756 Serine\threonine-protein kinase SIK3 OS=Homo sapiens OX=9606 GN=SIK3 PE=1 SV=4 4.37 2665.1 - 458473 - - - 1.1007 - 1.474 0.198 - 135.9 1 2 0 0.0011 8 0 0 0 1.75E+07 1.20E+06 - - - 1.6732 0.9996 221125_WJC_METTL3_EV_vs_WT_F02.12516.12516.2 0.000492 16-Sep K.TFSEVLAEK.K "sp|O75152|ZC11A_HUMAN,tr|E9PBY7|E9PBY7_HUMAN,tr|E9PQ61|E9PQ61_HUMAN" 3 1022.5284 0.71 13128 12516 2 1022.528904 512.2715 Zinc finger CCCH domain-containing protein 11A OS=Homo sapiens OX=9606 GN=ZC3H11A PE=1 SV=3 4.53 2665.7 - 679749 - - - 0.4665 - 1.67 0.391 - 196.1 1 2 0 0.0005 9 0 0 0 2.47E+07 3.46E+07 - - - 3.4124 0.9957 221125_WJC_METTL3_EV_vs_WT_F02.12520.12520.2 0.000111 14-Aug R.DVALLQGR[166.11].A "sp|Q9UNF1|MAGD2_HUMAN,tr|Q5H907|Q5H907_HUMAN,tr|Q5H909|Q5H909_HUMAN" 3 880.5006 0.74 13130 12520 2 880.502213 441.2576 Melanoma-associated antigen D2 OS=Homo sapiens OX=9606 GN=MAGED2 PE=1 SV=2 5.84 2666.1 - 1.07E+06 - - - 1.8478 - 1.777 0.136 - 234.9 1 2 0 0.0016 8 0 0 0 4.30E+07 5.85E+07 - - - 1.7789 0.9985 221125_WJC_METTL3_EV_vs_WT_F02.12521.12521.2 0.0051 18-Oct K.TLIEAGLPQK.V "sp|O43390|HNRPR_HUMAN,tr|A0A6Q8PH35|A0A6Q8PH35_HUMAN" 2 1068.6179 1.09 13131 12521 2 1068.620609 535.3162 Heterogeneous nuclear ribonucleoprotein R OS=Homo sapiens OX=9606 GN=HNRNPR PE=1 SV=1 5.66 2666.3 - 770775 - - - 2.5257 - 1.668 0.362 - 322 1 2 0 0.0027 10 0 0 0 2.11E+07 1.95E+07 - - - 3.142 0.7981 221125_WJC_METTL3_EV_vs_WT_F02.12523.12523.2 0.00022 18-Oct R.PTIINAENLK[136.11].G sp|Q5JSZ5|PRC2B_HUMAN 1 1119.6379 4.32 13133 12523 2 1119.639849 560.8262 Protein PRRC2B OS=Homo sapiens OX=9606 GN=PRRC2B PE=1 SV=2 6.43 2666.5 - 539266 - - - 1.7193 - 2.09 0.086 - 207.6 1 1 0 0.0019 10 0 0 0 6.16E+07 1.43E+07 - - - 1.7332 0.9988 221125_WJC_METTL3_EV_vs_WT_F02.12527.12527.2 0.0281 14-Aug K.QSLLLEER.N "sp|Q9UPS8|ANR26_HUMAN,tr|A0A6Q8PFU2|A0A6Q8PFU2_HUMAN,tr|E7ESJ3|E7ESJ3_HUMAN" 3 986.5397 1.87 13135 12527 2 986.53842 494.2771 Ankyrin repeat domain-containing protein 26 OS=Homo sapiens OX=9606 GN=ANKRD26 PE=1 SV=4 4.53 2667.1 - 821487 - - - -1.2569 - 1.691 0.253 - 220.6 1 2 0 -0.0012 8 0 0 0 1.59E+07 8.48E+06 - - - 2.4936 0.993 221125_WJC_METTL3_EV_vs_WT_F02.12531.12531.2 0.0273 14-Aug R.DVALLQGR.A "sp|Q9UNF1|MAGD2_HUMAN,tr|Q5H907|Q5H907_HUMAN,tr|Q5H909|Q5H909_HUMAN" 3 870.4923 0.74 13137 12531 2 870.492773 436.2534 Melanoma-associated antigen D2 OS=Homo sapiens OX=9606 GN=MAGED2 PE=1 SV=2 5.84 2667.5 - 1.11E+06 - - - 0.525 - 1.574 0.07 - 236.8 1 2 0 0.0005 8 0 0 0 4.29E+07 5.81E+07 - - - 0.926 0.9993 221125_WJC_METTL3_EV_vs_WT_F02.12535.12535.2 0.0438 14-Sep R.QLGLVVC[160.03]R[166.11].G "sp|Q9UK45|LSM7_HUMAN,tr|A0A087X2I5|A0A087X2I5_HUMAN" 2 953.5356 1.82 13140 12535 2 953.536925 477.7751 U6 snRNA-associated Sm-like protein LSm7 OS=Homo sapiens OX=9606 GN=LSM7 PE=1 SV=1 8.25 2667.9 - 2.48E+06 - - - 1.399 - 1.766 0.331 - 340.4 1 2 0 0.0013 8 0 0 0 3.13E+08 1.72E+08 - - - 3.2006 0.9998 221125_WJC_METTL3_EV_vs_WT_F02.12538.12538.2 0.000841 18-Sep K.LTEQLAGPLR[166.11].Q sp|P42285|MTREX_HUMAN 1 1106.6323 0.71 13142 12538 2 1106.632273 554.3234 Exosome RNA helicase MTR4 OS=Homo sapiens OX=9606 GN=MTREX PE=1 SV=3 6 2668.2 - 1.19E+06 - - - -0.0497 - 2.01 0.412 - 278.7 1 2 0 -0.0001 10 0 0 0 4.15E+07 5.83E+07 - - - 4.0327 0.9996 221125_WJC_METTL3_EV_vs_WT_F02.12540.12540.2 0.00189 14-Oct R.QLGLVVC[160.03]R.G "sp|Q9UK45|LSM7_HUMAN,tr|A0A087X2I5|A0A087X2I5_HUMAN" 2 943.5273 1.82 13143 12540 2 943.527851 472.7709 U6 snRNA-associated Sm-like protein LSm7 OS=Homo sapiens OX=9606 GN=LSM7 PE=1 SV=1 8.25 2668.5 - 4.33E+06 - - - 0.5617 - 1.937 0.301 - 476.1 1 2 0 0.0005 8 0 0 0 3.15E+08 1.74E+08 - - - 3.258 0.9991 221125_WJC_METTL3_EV_vs_WT_F02.12542.12542.2 0.00133 16-Nov K.VGLQVVAVK[136.11].A "sp|P10809|CH60_HUMAN,tr|A0A7I2V2X6|A0A7I2V2X6_HUMAN,tr|A0A7I2YQK6|A0A7I2YQK6_HUMAN,tr|A0A7I2V599|A0A7I2V599_HUMAN,tr|A0A7I2V5M1|A0A7I2V5M1_HUMAN" 5 919.5946 1.21 13144 12542 2 919.596289 460.8046 "60 kDa heat shock protein, mitochondrial OS=Homo sapiens OX=9606 GN=HSPD1 PE=1 SV=2" 8.72 2668.7 - 2.34E+06 - - - 1.8334 - 2.235 0.248 - 380.1 1 2 0 0.0017 9 0 0 0 1.68E+10 1.39E+10 - - - 3.1989 0.9998 221125_WJC_METTL3_EV_vs_WT_F02.12547.12547.2 9.39E-05 18-Aug R.AGETMYLYEK[136.11].A "sp|Q9H8V3|ECT2_HUMAN,tr|H7C3G1|H7C3G1_HUMAN" 2 1211.5624 6.69 13147 12547 2 1211.562386 606.7885 Protein ECT2 OS=Homo sapiens OX=9606 GN=ECT2 PE=1 SV=4 4.53 2669.2 - 251724 - - - 0.0083 - 1.889 0.486 - 231.5 1 2 0 0 10 0 0 0 4.07E+07 6.08E+06 - - - 4.406 0.9851 221125_WJC_METTL3_EV_vs_WT_F02.12548.12548.2 0.00031 22-Oct W.ELISNASDALDK.L "sp|Q58FF8|H90B2_HUMAN,sp|P08238|HS90B_HUMAN,sp|Q58FF6|H90B4_HUMAN,sp|Q58FF7|H90B3_HUMAN,sp|P14625|ENPL_HUMAN,tr|A0A7P0T917|A0A7P0T917_HUMAN,tr|A0A7P0Z405|A0A7P0Z405_HUMAN,tr|A0A7P0T823|A0A7P0T823_HUMAN,tr|A0A7P0TAE1|A0A7P0TAE1_HUMAN,tr|H0YIV0|H0YIV0_HUMAN,tr|A0A7P0T8R3|A0A7P0T8R3_HUMAN,tr|A0A7P0T885|A0A7P0T885_HUMAN,tr|A0A7P0TAY2|A0A7P0TAY2_HUMAN,tr|A0A087WT78|A0A087WT78_HUMAN,tr|F8W026|F8W026_HUMAN,tr|A0A7P0TBC2|A0A7P0TBC2_HUMAN,tr|A0A7P0TAT8|A0A7P0TAT8_HUMAN" 17 1274.6354 35.43 13148 12548 2 1274.635268 638.325 Putative heat shock protein HSP 90-beta 2 OS=Homo sapiens OX=9606 GN=HSP90AB2P PE=1 SV=2 4.03 2669.4 - 140223 - - - -0.1122 - 1.83 0.426 - 341.3 1 1 0 -0.0001 12 0 0 0 5.43E+06 1.53E+05 - - - 3.7774 0.7665 221125_WJC_METTL3_EV_vs_WT_F02.12549.12549.2 5.24 16-Apr K.LNEMSYELK.C "sp|Q5VU43|MYOME_HUMAN,tr|E9PQG4|E9PQG4_HUMAN,tr|A0A087WX83|A0A087WX83_HUMAN,tr|A0A075B749|A0A075B749_HUMAN" 4 1125.5376 0.79 13149 12549 2 1125.535461 563.7761 Myomegalin OS=Homo sapiens OX=9606 GN=PDE4DIP PE=1 SV=3 4.53 2669.5 - 109474 - - - -1.9102 - 0.94 0.073 - 30.7 12 2 0 -0.0022 9 0 0 0 3.77E+06 4.75E+06 - - - -1.0816 0.9998 221125_WJC_METTL3_EV_vs_WT_F02.12551.12551.2 0.000132 16-Aug K.NDLAVVDVR[166.11].L "sp|P19338|NUCL_HUMAN,tr|A0A7I2V506|A0A7I2V506_HUMAN,tr|A0A7I2V699|A0A7I2V699_HUMAN,tr|A0A7I2V2U7|A0A7I2V2U7_HUMAN,tr|A0A7I2V3F3|A0A7I2V3F3_HUMAN,tr|A0A7I2V428|A0A7I2V428_HUMAN,tr|A0A7I2V349|A0A7I2V349_HUMAN,tr|H7BY16|H7BY16_HUMAN,tr|A0A7I2V5M5|A0A7I2V5M5_HUMAN,tr|A0A7I2V2S8|A0A7I2V2S8_HUMAN,tr|C9JLB1|C9JLB1_HUMAN" 11 1009.5432 1 13150 12551 2 1009.542334 505.7789 Nucleolin OS=Homo sapiens OX=9606 GN=NCL PE=1 SV=3 4.21 2669.7 - 2.37E+07 - - - -0.837 - 2.069 0.428 - 307.3 1 2 0 -0.0008 9 0 0 0 5.97E+08 5.99E+08 - - - 4.3054 0.9992 221125_WJC_METTL3_EV_vs_WT_F02.12553.12553.2 6.06 16-Oct K.VGLQVVAVK.A "sp|P10809|CH60_HUMAN,tr|A0A7I2V2X6|A0A7I2V2X6_HUMAN,tr|A0A7I2YQK6|A0A7I2YQK6_HUMAN,tr|A0A7I2V599|A0A7I2V599_HUMAN,tr|A0A7I2V5M1|A0A7I2V5M1_HUMAN" 5 911.5804 1.21 13151 12553 2 911.580545 456.7975 "60 kDa heat shock protein, mitochondrial OS=Homo sapiens OX=9606 GN=HSPD1 PE=1 SV=2" 8.72 2669.9 - 6.92E+06 - - - 0.1558 - 2.195 0.172 - 283.2 1 2 0 0.0001 9 0 0 0 1.68E+10 1.39E+10 - - - 2.5858 0.9997 221125_WJC_METTL3_EV_vs_WT_F02.12555.12555.2 0.000271 14-Aug K.VFNVGEYR.R "sp|Q16875|F263_HUMAN,tr|A0A1W2PR17|A0A1W2PR17_HUMAN,tr|Q5W015|Q5W015_HUMAN,tr|A0A1W2PNV9|A0A1W2PNV9_HUMAN,tr|F2Z2I2|F2Z2I2_HUMAN,tr|Q5VX20|Q5VX20_HUMAN" 6 982.4872 2.65 13153 12555 2 982.48822 492.2509 "6-phosphofructo-2-kinase\fructose-2,6-bisphosphatase 3 OS=Homo sapiens OX=9606 GN=PFKFB3 PE=1 SV=1" 5.97 2670.1 - 1.97E+06 - - - 1.0066 - 1.609 0.461 - 247 1 2 0 0.001 8 0 0 0 2.22E+08 8.37E+07 - - - 3.8801 0.9992 221125_WJC_METTL3_EV_vs_WT_F02.12556.12556.2 0.0303 20-Sep K.VTLGTQPTVLR[166.11].T "sp|Q16531|DDB1_HUMAN,tr|A0A7P0TAK7|A0A7P0TAK7_HUMAN,tr|A0A7P0T870|A0A7P0T870_HUMAN,tr|A0A7P0TB30|A0A7P0TB30_HUMAN,tr|A0A7P0Z3Z5|A0A7P0Z3Z5_HUMAN,tr|F5GY55|F5GY55_HUMAN,tr|A0A7P0Z4B9|A0A7P0Z4B9_HUMAN,tr|A0A7P0T965|A0A7P0T965_HUMAN" 8 1193.7007 0.7 13154 12556 2 1193.701189 597.8576 DNA damage-binding protein 1 OS=Homo sapiens OX=9606 GN=DDB1 PE=1 SV=1 9.72 2670.2 - 1.29E+06 - - - 0.3745 - 1.856 0.264 - 174.9 1 2 0 0.0004 11 0 0 0 4.74E+07 6.76E+07 - - - 2.6637 1 221125_WJC_METTL3_EV_vs_WT_F02.12564.12564.2 2.37E-07 20-Nov K.FDGAVEAVAVR.Q "sp|O60476|MA1A2_HUMAN,tr|H0Y7H1|H0Y7H1_HUMAN,tr|H0Y543|H0Y543_HUMAN" 3 1132.5877 1.87 13161 12564 2 1132.588627 567.3011 "Mannosyl-oligosaccharide 1,2-alpha-mannosidase IB OS=Homo sapiens OX=9606 GN=MAN1A2 PE=1 SV=1" 4.37 2671.1 - 1.19E+06 - - - 0.8423 - 2.322 0.598 - 427.3 1 2 0 0.001 11 0 0 0 1.17E+08 6.24E+07 - - - 5.7365 0.9883 221125_WJC_METTL3_EV_vs_WT_F02.12566.12566.2 0.249 12-May R.SMTLEIR[166.11].E "sp|P31040|SDHA_HUMAN,tr|A0A087X1I3|A0A087X1I3_HUMAN,tr|D6RFM5|D6RFM5_HUMAN,tr|A0A494C1T6|A0A494C1T6_HUMAN" 4 858.4509 0.46 13162 12566 2 858.44932 430.2327 "Succinate dehydrogenase [ubiquinone] flavoprotein subunit, mitochondrial OS=Homo sapiens OX=9606 GN=SDHA PE=1 SV=2" 5.72 2671.3 - 3.61E+06 - - - -1.7928 - 1.118 0.209 - 111.8 1 2 0 -0.0015 7 0 0 0 4.47E+07 9.71E+07 - - - 0.9376 0.9996 221125_WJC_METTL3_EV_vs_WT_F02.12568.12568.2 0.000473 14-Aug K.DGFVALSK.A "sp|Q92499|DDX1_HUMAN,tr|A0A7I2V2M5|A0A7I2V2M5_HUMAN,tr|A0A087X2G1|A0A087X2G1_HUMAN,tr|A0A7I2V430|A0A7I2V430_HUMAN,tr|A0A7I2V421|A0A7I2V421_HUMAN,tr|A0A7I2V4F0|A0A7I2V4F0_HUMAN,tr|A0A7I2V5X8|A0A7I2V5X8_HUMAN,tr|A0A7I2V4J3|A0A7I2V4J3_HUMAN,tr|A0A087WZ71|A0A087WZ71_HUMAN,tr|A0A7I2YQ77|A0A7I2YQ77_HUMAN" 10 835.444 1.17 13163 12568 2 835.443499 418.7293 ATP-dependent RNA helicase DDX1 OS=Homo sapiens OX=9606 GN=DDX1 PE=1 SV=2 5.84 2671.5 - 7.78E+06 - - - -0.5626 - 1.547 0.412 - 230.6 1 2 0 -0.0005 8 0 0 0 3.38E+08 2.89E+08 - - - 3.3998 0.9998 221125_WJC_METTL3_EV_vs_WT_F02.12573.12573.2 0.000235 16-Jul K.YLYPYEC[160.03]EK.R "sp|Q99856|ARI3A_HUMAN,tr|K7EJ04|K7EJ04_HUMAN" 2 1263.5482 2.19 13168 12573 2 1263.547974 632.7814 AT-rich interactive domain-containing protein 3A OS=Homo sapiens OX=9606 GN=ARID3A PE=1 SV=2 4.53 2672 - 205931 - - - -0.1599 - 1.392 0.559 - 91.2 1 2 0 -0.0002 9 0 0 0 4.21E+06 1.92E+06 - - - 4.1266 0.9878 221125_WJC_METTL3_EV_vs_WT_F02.12582.12582.2 0.866 18-Jul K.LPVALDPGAK[136.11].L sp|P04843|RPN1_HUMAN 1 987.5844 1.46 13173 12582 2 987.584839 494.7995 Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit 1 OS=Homo sapiens OX=9606 GN=RPN1 PE=1 SV=1 5.84 2673 - 2.68E+06 - - - 0.4121 - 1.325 0.095 - 106.8 1 2 0 0.0004 10 0 0 0 3.77E+08 2.59E+08 - - - 0.528 0.9997 221125_WJC_METTL3_EV_vs_WT_F02.12583.12583.2 0.0161 20-Sep K.VTLGTQPTVLR.T "sp|Q16531|DDB1_HUMAN,tr|A0A7P0TAK7|A0A7P0TAK7_HUMAN,tr|A0A7P0T870|A0A7P0T870_HUMAN,tr|A0A7P0TB30|A0A7P0TB30_HUMAN,tr|A0A7P0Z3Z5|A0A7P0Z3Z5_HUMAN,tr|F5GY55|F5GY55_HUMAN,tr|A0A7P0Z4B9|A0A7P0Z4B9_HUMAN,tr|A0A7P0T965|A0A7P0T965_HUMAN" 8 1183.6925 0.7 13174 12583 2 1183.691354 592.8535 DNA damage-binding protein 1 OS=Homo sapiens OX=9606 GN=DDB1 PE=1 SV=1 9.72 2673.1 - 1.34E+06 - - - -0.9445 - 1.936 0.397 - 280.9 1 2 0 -0.0011 11 0 0 0 4.74E+07 6.76E+07 - - - 3.76 1 221125_WJC_METTL3_EV_vs_WT_F02.12584.12584.2 1.59E-11 Oct-38 R.FSSC[160.03]GGGGGSFGAGGGFGSR.S sp|P04264|K2C1_HUMAN 1 1764.7274 999 13175 12584 2 1764.724791 883.371 "Keratin, type II cytoskeletal 1 OS=Homo sapiens OX=9606 GN=KRT1 PE=1 SV=6" 8.25 2673.3 - 255754 - - - -1.496 - 2.703 0.755 - 106.8 1 2 0 -0.0026 20 0 0 0 5.22E+06 0.00E+00 - - - 7.0613 0.9998 221125_WJC_METTL3_EV_vs_WT_F02.12587.12587.2 0.00208 16-Oct R.QLLLTADDR.V "sp|P04075|ALDOA_HUMAN,tr|H3BR04|H3BR04_HUMAN,tr|H3BMQ8|H3BMQ8_HUMAN,tr|H3BU78|H3BU78_HUMAN,tr|H3BQN4|H3BQN4_HUMAN,tr|H3BUH7|H3BUH7_HUMAN,tr|J3KPS3|J3KPS3_HUMAN,tr|H3BPS8|H3BPS8_HUMAN" 8 1043.5611 1.43 13176 12587 2 1043.561515 522.7878 Fructose-bisphosphate aldolase A OS=Homo sapiens OX=9606 GN=ALDOA PE=1 SV=2 4.21 2673.7 - 3.96E+06 - - - 0.3747 - 1.995 0.444 - 472.7 1 2 0 0.0004 9 0 0 0 1.25E+08 8.73E+07 - - - 4.3183 0.9995 221125_WJC_METTL3_EV_vs_WT_F02.12591.12591.2 0.0233 16-Sep K.GDYPLEAVR.M "sp|P14618|KPYM_HUMAN,tr|B4DNK4|B4DNK4_HUMAN,tr|A0A804F6T5|A0A804F6T5_HUMAN,tr|H3BTN5|H3BTN5_HUMAN,tr|H3BR70|H3BR70_HUMAN,tr|A0A804F729|A0A804F729_HUMAN" 6 1018.5084 1.54 13178 12591 2 1018.507883 510.2615 Pyruvate kinase PKM OS=Homo sapiens OX=9606 GN=PKM PE=1 SV=4 4.37 2674.1 - 1.07E+06 - - - -0.4683 - 1.474 0.388 - 242.2 1 2 0 -0.0005 9 0 0 0 2.43E+08 1.59E+08 - - - 3.0291 0.9999 221125_WJC_METTL3_EV_vs_WT_F02.12597.12597.2 3.10E-07 16-Oct K.NDLAVVDVR.L "sp|P19338|NUCL_HUMAN,tr|A0A7I2V506|A0A7I2V506_HUMAN,tr|A0A7I2V699|A0A7I2V699_HUMAN,tr|A0A7I2V2U7|A0A7I2V2U7_HUMAN,tr|A0A7I2V3F3|A0A7I2V3F3_HUMAN,tr|A0A7I2V428|A0A7I2V428_HUMAN,tr|A0A7I2V349|A0A7I2V349_HUMAN,tr|H7BY16|H7BY16_HUMAN,tr|A0A7I2V5M5|A0A7I2V5M5_HUMAN,tr|A0A7I2V2S8|A0A7I2V2S8_HUMAN,tr|C9JLB1|C9JLB1_HUMAN" 11 999.5349 1 13182 12597 2 999.534106 500.7747 Nucleolin OS=Homo sapiens OX=9606 GN=NCL PE=1 SV=3 4.21 2674.8 - 4.32E+06 - - - -0.8034 - 2.382 0.537 - 481.3 1 2 0 -0.0008 9 0 0 0 5.98E+08 5.99E+08 - - - 5.518 0.9518 221125_WJC_METTL3_EV_vs_WT_F02.12601.12601.2 0.025 16-Jul R.LLEGEDAHL.T "sp|Q04695|K1C17_HUMAN,sp|P02533|K1C14_HUMAN,sp|P08779|K1C16_HUMAN,tr|A0A3B3IS58|A0A3B3IS58_HUMAN,tr|F5GWP8|F5GWP8_HUMAN" 5 995.4924 - 13184 12601 2 995.49096 498.7535 "Keratin, type I cytoskeletal 17 OS=Homo sapiens OX=9606 GN=KRT17 PE=1 SV=2" 4.13 2675.3 - 4.70E+06 - - - -1.4214 - 1.404 0.389 - 96.6 1 1 0 -0.0014 9 0 0 0 - - - - - 2.8954 0.9995 221125_WJC_METTL3_EV_vs_WT_F02.12602.12602.2 0.00401 18-Sep K.LVMDQISEAR.D "sp|Q9H0E3|SP130_HUMAN,tr|A0A2R8YDB8|A0A2R8YDB8_HUMAN,tr|H7BXF5|H7BXF5_HUMAN" 3 1160.586 1.78 13185 12602 2 1160.587537 581.3003 Histone deacetylase complex subunit SAP130 OS=Homo sapiens OX=9606 GN=SAP130 PE=1 SV=1 4.37 2675.4 - 697832 - - - 1.3605 - 1.729 0.405 - 273.6 1 2 0 0.0016 10 0 0 0 1.62E+07 9.11E+06 - - - 3.5602 0.9282 221125_WJC_METTL3_EV_vs_WT_F02.12606.12606.2 2.83 12-Jun M.FSLDSFR[166.11].K "sp|Q7L2E3|DHX30_HUMAN,tr|F6R0H4|F6R0H4_HUMAN" 2 880.4318 0.91 13187 12606 2 880.430589 441.2232 ATP-dependent RNA helicase DHX30 OS=Homo sapiens OX=9606 GN=DHX30 PE=1 SV=1 5.84 2675.9 - 4.32E+06 - - - -1.4186 - 1.232 0 - 165.1 2 2 0 -0.0012 7 0 0 0 1.21E+08 1.33E+08 - - - -0.4328 0.98 221125_WJC_METTL3_EV_vs_WT_F02.12608.12608.2 0.00631 16-Sep K.ILIVTQTPH.Y "sp|Q6PKG0|LARP1_HUMAN,tr|A0A0B4J210|A0A0B4J210_HUMAN,tr|E5RH50|E5RH50_HUMAN" 3 1020.5968 - 13189 12608 2 1020.595573 511.3057 La-related protein 1 OS=Homo sapiens OX=9606 GN=LARP1 PE=1 SV=2 6.74 2676.1 - 1.73E+06 - - - -1.1836 - 1.802 0.406 - 257.6 1 1 0 -0.0012 9 0 0 0 - - - - - 3.743 0.9983 221125_WJC_METTL3_EV_vs_WT_F02.12620.12620.2 0.0902 14-Aug R.LLYEIQNR.D sp|Q01804|OTUD4_HUMAN 1 1047.5713 1.79 13196 12620 2 1047.571288 524.7929 OTU domain-containing protein 4 OS=Homo sapiens OX=9606 GN=OTUD4 PE=1 SV=4 6 2677.6 - 1.92E+06 - - - -0.0067 - 1.464 0.232 - 206.8 1 2 0 0 8 0 0 0 1.23E+08 6.89E+07 - - - 1.9041 0.9991 221125_WJC_METTL3_EV_vs_WT_F02.12623.12623.2 0.00785 14-Aug K.TAVEFLSK[136.11].A "sp|Q7L2E3|DHX30_HUMAN,tr|H7BXY3|H7BXY3_HUMAN" 2 901.5 0.96 13198 12623 2 901.499278 451.7573 ATP-dependent RNA helicase DHX30 OS=Homo sapiens OX=9606 GN=DHX30 PE=1 SV=1 5.66 2677.9 - 1.28E+06 - - - -0.8386 - 1.532 0.31 - 257.4 1 2 0 -0.0008 8 0 0 0 5.77E+07 6.04E+07 - - - 2.617 0.9965 221125_WJC_METTL3_EV_vs_WT_F02.12628.12628.2 0.0164 14-Jun K.DGFVALSK[136.11].A "sp|Q92499|DDX1_HUMAN,tr|A0A7I2V2M5|A0A7I2V2M5_HUMAN,tr|A0A087X2G1|A0A087X2G1_HUMAN,tr|A0A7I2V430|A0A7I2V430_HUMAN,tr|A0A7I2V421|A0A7I2V421_HUMAN,tr|A0A7I2V4F0|A0A7I2V4F0_HUMAN,tr|A0A7I2V5X8|A0A7I2V5X8_HUMAN,tr|A0A7I2V4J3|A0A7I2V4J3_HUMAN,tr|A0A087WZ71|A0A087WZ71_HUMAN,tr|A0A7I2YQ77|A0A7I2YQ77_HUMAN" 10 843.4582 1.23 13201 12628 2 843.456231 422.7364 ATP-dependent RNA helicase DDX1 OS=Homo sapiens OX=9606 GN=DDX1 PE=1 SV=2 5.84 2678.4 - 3.47E+06 - - - -2.2977 - 1.382 0.286 - 106.6 1 2 0 -0.0019 8 0 0 0 3.38E+08 2.76E+08 - - - 2.1285 0.9989 221125_WJC_METTL3_EV_vs_WT_F02.12629.12629.2 0.0221 16-Sep R.GVISTPVIR.T "sp|Q9NZB2|F120A_HUMAN,tr|A0A0C4DG79|A0A0C4DG79_HUMAN,tr|A0A494C0Y9|A0A494C0Y9_HUMAN" 3 940.5706 0.69 13202 12629 2 940.569153 471.2926 Constitutive coactivator of PPAR-gamma-like protein 1 OS=Homo sapiens OX=9606 GN=FAM120A PE=1 SV=2 9.75 2678.5 - 3.01E+06 - - - -1.5023 - 1.566 0.316 - 194.5 1 2 0 -0.0014 9 0 0 0 1.18E+08 1.71E+08 - - - 2.6721 0.9996 221125_WJC_METTL3_EV_vs_WT_F02.12630.12630.2 0.311 14-Oct R.LLDQIVEK.G "sp|Q96AE4|FUBP1_HUMAN,tr|E9PEB5|E9PEB5_HUMAN,tr|C9JSZ1|C9JSZ1_HUMAN" 3 956.5542 1.23 13203 12630 2 956.554162 479.2844 Far upstream element-binding protein 1 OS=Homo sapiens OX=9606 GN=FUBP1 PE=1 SV=3 4.37 2678.6 - 2.04E+06 - - - -0.0889 - 1.93 0.289 - 224.5 1 2 0 -0.0001 8 0 0 0 1.38E+08 1.12E+08 - - - 3.1586 0.9994 221125_WJC_METTL3_EV_vs_WT_F02.12631.12631.2 0.0706 14-Aug R.LLYEIQNR[166.11].D sp|Q01804|OTUD4_HUMAN 1 1057.5796 1.81 13204 12631 2 1057.577977 529.7971 OTU domain-containing protein 4 OS=Homo sapiens OX=9606 GN=OTUD4 PE=1 SV=4 6 2678.7 - 1.55E+06 - - - -1.5015 - 1.738 0.353 - 222 1 2 0 -0.0016 8 0 0 0 1.21E+08 6.69E+07 - - - 3.3148 0.9998 221125_WJC_METTL3_EV_vs_WT_F02.12633.12633.2 7.65E-06 22-Sep R.MVPAGMGAGLER.M "sp|P52272|HNRPM_HUMAN,tr|M0R2I7|M0R2I7_HUMAN,tr|A0A087X0X3|A0A087X0X3_HUMAN,tr|M0QZM1|M0QZM1_HUMAN" 4 1187.5791 1.59 13205 12633 2 1187.578104 594.7968 Heterogeneous nuclear ribonucleoprotein M OS=Homo sapiens OX=9606 GN=HNRNPM PE=1 SV=3 5.75 2679 - 681195 - - - -0.8378 - 1.832 0.529 - 332.7 1 2 0 -0.001 12 0 0 0 1.14E+09 7.18E+08 - - - 4.5408 0.9999 221125_WJC_METTL3_EV_vs_WT_F02.12635.12635.2 1.28E-05 18-Nov K.FGEVVDC[160.03]TIK.M "sp|Q99729|ROAA_HUMAN,sp|Q14103|HNRPD_HUMAN,sp|O14979|HNRDL_HUMAN,tr|H0Y8G5|H0Y8G5_HUMAN,tr|A0A087WUK2|A0A087WUK2_HUMAN,tr|D6RF44|D6RF44_HUMAN,tr|D6RD83|D6RD83_HUMAN,tr|D6R9P3|D6R9P3_HUMAN,tr|D6RBQ9|D6RBQ9_HUMAN,tr|D6RAF8|D6RAF8_HUMAN,tr|H0YA96|H0YA96_HUMAN,tr|D6RD18|D6RD18_HUMAN,tr|D6RBZ0|D6RBZ0_HUMAN" 13 1166.5642 1.18 13206 12635 2 1166.562686 584.2894 Heterogeneous nuclear ribonucleoprotein A\B OS=Homo sapiens OX=9606 GN=HNRNPAB PE=1 SV=2 4.37 2679.2 - 2.77E+07 - - - -1.2644 - 2.386 0.531 - 407.5 1 2 0 -0.0015 10 0 0 0 8.05E+08 6.82E+08 - - - 5.3899 0.9985 221125_WJC_METTL3_EV_vs_WT_F02.12636.12636.2 0.0183 14-Aug K.TAVEFLSK.A "sp|Q7L2E3|DHX30_HUMAN,tr|H7BXY3|H7BXY3_HUMAN" 2 893.4858 0.96 13207 12636 2 893.487265 447.7502 ATP-dependent RNA helicase DHX30 OS=Homo sapiens OX=9606 GN=DHX30 PE=1 SV=1 5.66 2679.2 - 2.44E+06 - - - 1.6016 - 1.499 0.309 - 221.8 1 2 0 0.0014 8 0 0 0 5.77E+07 6.04E+07 - - - 2.5437 0.9977 221125_WJC_METTL3_EV_vs_WT_F02.12638.12638.2 0.000523 16-Aug R.GSDIIIVGR.G sp|P11172|UMPS_HUMAN 1 928.5342 1.14 13209 12638 2 928.530774 465.2744 Uridine 5'-monophosphate synthase OS=Homo sapiens OX=9606 GN=UMPS PE=1 SV=1 5.84 2679.4 - 2.38E+06 - - - -3.6692 - 1.737 0.393 - 184.6 1 2 0 -0.0034 9 0 0 0 6.54E+07 5.73E+07 - - - 3.5401 0.999 221125_WJC_METTL3_EV_vs_WT_F02.12643.12643.2 9.74E-05 14-Sep R.LYEWTTEK[136.11].E "sp|Q16531|DDB1_HUMAN,tr|A0A7P0TAK7|A0A7P0TAK7_HUMAN,tr|A0A7P0T870|A0A7P0T870_HUMAN,tr|A0A7P0TB30|A0A7P0TB30_HUMAN,tr|A0A7P0Z3Z5|A0A7P0Z3Z5_HUMAN,tr|F5GY55|F5GY55_HUMAN,tr|A0A7P0Z4B9|A0A7P0Z4B9_HUMAN,tr|A0A7P0T965|A0A7P0T965_HUMAN" 8 1076.527 0.81 13212 12643 2 1076.524015 539.2708 DNA damage-binding protein 1 OS=Homo sapiens OX=9606 GN=DDB1 PE=1 SV=1 4.53 2680 - 1.08E+06 - - - -2.7514 - 1.655 0.428 - 256.3 1 2 0 -0.003 8 0 0 0 3.43E+07 4.25E+07 - - - 3.7207 0.9853 221125_WJC_METTL3_EV_vs_WT_F02.12644.12644.2 1.56 14-Jul R.LLDQIVEK[136.11].G "sp|Q96AE4|FUBP1_HUMAN,tr|E9PEB5|E9PEB5_HUMAN,tr|C9JSZ1|C9JSZ1_HUMAN" 3 964.5684 1.23 13213 12644 2 964.566386 483.2915 Far upstream element-binding protein 1 OS=Homo sapiens OX=9606 GN=FUBP1 PE=1 SV=3 4.37 2680 - 3.45E+06 - - - -2.1367 - 1.293 0.153 - 94.2 1 2 0 -0.0021 8 0 0 0 1.38E+08 1.12E+08 - - - 0.9454 0.999 221125_WJC_METTL3_EV_vs_WT_F02.12645.12645.2 0.0397 16-Sep R.YLENYDAIR.V "sp|P15374|UCHL3_HUMAN,tr|A0A087WTB8|A0A087WTB8_HUMAN,tr|Q5TBK7|Q5TBK7_HUMAN" 3 1155.556 0.05 13214 12645 2 1155.553847 578.7853 Ubiquitin carboxyl-terminal hydrolase isozyme L3 OS=Homo sapiens OX=9606 GN=UCHL3 PE=1 SV=1 4.37 2680.2 - 600350 - - - -1.8961 - 1.638 0.34 - 213 1 2 0 -0.0022 9 0 0 0 1.65E+07 3.61E+08 - - - 2.9792 0.9999 221125_WJC_METTL3_EV_vs_WT_F02.12652.12652.2 0.000354 20-Sep R.MNSLEMTPAVR[166.11].Q "sp|P09601|HMOX1_HUMAN,tr|A0A7I2V3M0|A0A7I2V3M0_HUMAN,tr|A0A7I2V3I1|A0A7I2V3I1_HUMAN" 3 1257.6085 1.51 13217 12652 2 1257.607838 629.8115 Heme oxygenase 1 OS=Homo sapiens OX=9606 GN=HMOX1 PE=1 SV=1 5.75 2681.1 - 431045 - - - -0.5248 - 2.194 0.505 - 337.4 1 2 0 -0.0007 11 0 0 0 2.54E+07 1.68E+07 - - - 4.8963 0.8668 221125_WJC_METTL3_EV_vs_WT_F02.12661.12661.2 1.3 12-May K.LMPTQWR.T sp|Q99459|CDC5L_HUMAN 1 930.4746 1.61 13222 12661 2 930.474761 466.2446 Cell division cycle 5-like protein OS=Homo sapiens OX=9606 GN=CDC5L PE=1 SV=2 9.75 2682.1 - 2.11E+06 - - - 0.2192 - 0.916 0.021 - 96.8 1 2 0 0.0002 7 0 0 0 1.22E+08 7.58E+07 - - - -1.082 0.9997 221125_WJC_METTL3_EV_vs_WT_F02.12662.12662.2 0.0001 26-Aug K.IIPQGADSTMLATK.T "sp|P35658|NU214_HUMAN,tr|A0A0A0MSW3|A0A0A0MSW3_HUMAN,tr|H0YF36|H0YF36_HUMAN,tr|A0A494C1F2|A0A494C1F2_HUMAN" 4 1444.7596 2.14 13223 12662 2 1444.760671 723.3871 Nuclear pore complex protein Nup214 OS=Homo sapiens OX=9606 GN=NUP214 PE=1 SV=2 5.84 2682.2 - 245885 - - - 0.7648 - 1.66 0.454 - 117.4 1 2 0 0.0011 14 0 0 0 1.56E+07 7.32E+06 - - - 3.6657 0.9992 221125_WJC_METTL3_EV_vs_WT_F02.12665.12665.2 0.00124 12-Jul K.MNFSTLR.N "sp|Q9Y244|POMP_HUMAN,tr|A0A1W2PS02|A0A1W2PS02_HUMAN" 2 867.4273 1.52 13224 12665 2 867.426525 434.7209 Proteasome maturation protein OS=Homo sapiens OX=9606 GN=POMP PE=1 SV=1 9.5 2682.6 - 2.84E+06 - - - -0.8623 - 1.609 0.291 - 221.8 1 2 0 -0.0007 7 0 0 0 2.53E+08 1.67E+08 - - - 2.6971 0.9953 221125_WJC_METTL3_EV_vs_WT_F02.12666.12666.2 0.0189 12-Jul K.MNFSTLR[166.11].N "sp|Q9Y244|POMP_HUMAN,tr|A0A1W2PS02|A0A1W2PS02_HUMAN" 2 877.4355 1.51 13225 12666 2 877.433253 439.725 Proteasome maturation protein OS=Homo sapiens OX=9606 GN=POMP PE=1 SV=1 9.5 2682.6 - 1.79E+06 - - - -2.6099 - 1.588 0.213 - 215.4 1 2 0 -0.0023 7 0 0 0 2.52E+08 1.67E+08 - - - 2.0789 0.9998 221125_WJC_METTL3_EV_vs_WT_F02.12673.12673.2 2.49E-05 20-Sep R.MNSLEMTPAVR.Q "sp|P09601|HMOX1_HUMAN,tr|A0A7I2V3M0|A0A7I2V3M0_HUMAN,tr|A0A7I2V3I1|A0A7I2V3I1_HUMAN" 3 1247.6002 1.51 13229 12673 2 1247.598516 624.8074 Heme oxygenase 1 OS=Homo sapiens OX=9606 GN=HMOX1 PE=1 SV=1 5.75 2683.5 - 722968 - - - -1.3722 - 2.057 0.543 - 267.8 1 2 0 -0.0017 11 0 0 0 2.54E+07 1.68E+07 - - - 5.0022 0.9994 221125_WJC_METTL3_EV_vs_WT_F02.12676.12676.2 0.0171 18-Sep K.ILMGNEELTR[166.11].L "sp|Q96FV9|THOC1_HUMAN,tr|A0A087WWS1|A0A087WWS1_HUMAN,tr|R4GMN4|R4GMN4_HUMAN" 3 1184.6099 4.49 13231 12676 2 1184.609979 593.3122 THO complex subunit 1 OS=Homo sapiens OX=9606 GN=THOC1 PE=1 SV=1 4.53 2683.8 - 356705 - - - 0.0853 - 1.698 0.315 - 212.6 1 2 0 0.0001 10 0 0 0 6.60E+07 1.47E+07 - - - 2.8454 0.9777 221125_WJC_METTL3_EV_vs_WT_F02.12677.12677.2 0.404 12-Jun K.LMPTQWR[166.11].T sp|Q99459|CDC5L_HUMAN 1 940.4828 1.71 13232 12677 2 940.481764 471.2487 Cell division cycle 5-like protein OS=Homo sapiens OX=9606 GN=CDC5L PE=1 SV=2 9.75 2683.9 - 2.51E+06 - - - -1.1303 - 1.032 0.149 - 125.3 1 2 0 -0.0011 7 0 0 0 1.21E+08 7.10E+07 - - - 0.241 0.9992 221125_WJC_METTL3_EV_vs_WT_F02.12687.12687.2 0.0453 18-Aug K.ALGLDSESIR.A sp|Q9UGR2|Z3H7B_HUMAN 1 1059.556 0.34 13238 12687 2 1059.555396 530.7853 Zinc finger CCCH domain-containing protein 7B OS=Homo sapiens OX=9606 GN=ZC3H7B PE=1 SV=2 4.37 2684.9 - 858342 - - - -0.6059 - 1.587 0.315 - 174.3 1 2 0 -0.0006 10 0 0 0 1.43E+07 4.24E+07 - - - 2.6565 0.9375 221125_WJC_METTL3_EV_vs_WT_F02.12688.12688.2 0.0301 14-Aug K.EFEDDLVK.E "sp|O43148|MCES_HUMAN,tr|K7EPP5|K7EPP5_HUMAN" 2 993.4655 1.15 13239 12688 2 993.459637 497.74 mRNA cap guanine-N7 methyltransferase OS=Homo sapiens OX=9606 GN=RNMT PE=1 SV=1 3.92 2685.1 - 661380 - - - -5.8935 - 1.251 0.29 - 179 1 2 0 -0.0059 8 0 0 0 6.31E+07 5.49E+07 - - - 1.8565 0.9965 221125_WJC_METTL3_EV_vs_WT_F02.12692.12692.2 0.946 12-Aug K.LDLLTSK.C "sp|Q6ULP2|AFTIN_HUMAN,tr|B8ZZI9|B8ZZI9_HUMAN" 2 788.4644 0.78 13241 12692 2 788.46392 395.2395 Aftiphilin OS=Homo sapiens OX=9606 GN=AFTPH PE=1 SV=3 5.84 2685.6 - 1.56E+06 - - - -0.5707 - 1.708 0.088 - 194.5 1 2 0 -0.0004 7 0 0 0 4.21E+07 5.42E+07 - - - 1.387 0.997 221125_WJC_METTL3_EV_vs_WT_F02.12694.12694.2 0.199 14-Jul R.AELGEYIR.R "sp|Q14204|DYHC1_HUMAN,tr|A0A7P0T8N2|A0A7P0T8N2_HUMAN,tr|A0A7P0T9C4|A0A7P0T9C4_HUMAN,tr|A0A7P0TBJ7|A0A7P0TBJ7_HUMAN,tr|A0A804HHY6|A0A804HHY6_HUMAN,tr|A0A7P0T9K2|A0A7P0T9K2_HUMAN,tr|A0A7P0TB64|A0A7P0TB64_HUMAN,tr|A0A2R8Y706|A0A2R8Y706_HUMAN,tr|A0A7P0T916|A0A7P0T916_HUMAN,tr|A0A7P0TB75|A0A7P0TB75_HUMAN,tr|A0A7P0T8W5|A0A7P0T8W5_HUMAN,tr|A0A7P0TAF3|A0A7P0TAF3_HUMAN,tr|A0A7P0T9F1|A0A7P0T9F1_HUMAN,tr|A0A7P0TAW9|A0A7P0TAW9_HUMAN,tr|A0A2R8YGC7|A0A2R8YGC7_HUMAN,tr|A0A7P0TA13|A0A7P0TA13_HUMAN,tr|A0A7P0TAV5|A0A7P0TAV5_HUMAN,tr|A0A7P0T7V5|A0A7P0T7V5_HUMAN,tr|A0A7P0T9R4|A0A7P0T9R4_HUMAN,tr|A0A2R8Y5T0|A0A2R8Y5T0_HUMAN,tr|A0A7P0T990|A0A7P0T990_HUMAN,tr|A0A7P0T942|A0A7P0T942_HUMAN,tr|A0A2R8YFZ7|A0A2R8YFZ7_HUMAN,tr|A0A7P0T825|A0A7P0T825_HUMAN,tr|A0A2R8Y6H2|A0A2R8Y6H2_HUMAN,tr|A0A7P0TAM4|A0A7P0TAM4_HUMAN" 26 949.4869 0.68 13242 12694 2 949.48736 475.7507 Cytoplasmic dynein 1 heavy chain 1 OS=Homo sapiens OX=9606 GN=DYNC1H1 PE=1 SV=5 4.53 2685.8 - 2.07E+06 - - - 0.4887 - 1.206 0.263 - 156.9 1 2 0 0.0005 8 0 0 0 4.24E+07 6.24E+07 - - - 1.5483 0.7699 221125_WJC_METTL3_EV_vs_WT_F02.12711.12711.2 0.82 12-Jun K.DLVTSLK[136.11].D sp|P13674|P4HA1_HUMAN 1 782.4629 3.76 13255 12711 2 782.459113 392.2387 Prolyl 4-hydroxylase subunit alpha-1 OS=Homo sapiens OX=9606 GN=P4HA1 PE=1 SV=2 5.84 2687.7 - 1.35E+06 - - - -4.8654 - 1.265 0.066 - 142.4 1 2 0 -0.0038 7 0 0 0 2.25E+08 5.98E+07 - - - 0.2721 1 221125_WJC_METTL3_EV_vs_WT_F02.12716.12716.3 1.56E-08 20/68 K.YVHYEIDAC[160.03]MDSEAPGSK[136.11].D "sp|Q86U44|MTA70_HUMAN,tr|H0YFV6|H0YFV6_HUMAN" 2 2078.8805 0 13258 12716 3 2079.876891 693.9674 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 4.31 2688.4 - 1.32E+06 - - - 479.2959 - 3.439 0.674 - 403.2 1 2 0 0.9964 18 0 0 0 2.17E+05 6.04E+07 - - - 8.8542 0.9827 221125_WJC_METTL3_EV_vs_WT_F02.12725.12725.2 0.00243 16-Oct P.PVQVSPLIK.L sp|P56385|ATP5I_HUMAN 1 979.6066 1.07 13265 12725 2 979.606625 490.8106 "ATP synthase subunit e, mitochondrial OS=Homo sapiens OX=9606 GN=ATP5ME PE=1 SV=2" 9.18 2689.5 - 755949 - - - 0.0082 - 1.826 0.382 - 302 1 1 0 0 9 0 0 0 2.89E+07 2.69E+07 - - - 3.6044 0.9995 221125_WJC_METTL3_EV_vs_WT_F02.12727.12727.2 0.000462 16-Aug R.FTEYSSLYK[136.11].H "sp|P36508|ZNF76_HUMAN,sp|P52747|ZN143_HUMAN,tr|E7EX64|E7EX64_HUMAN,tr|E7EN86|E7EN86_HUMAN" 4 1144.5532 2.82 13267 12727 2 1144.554924 573.2839 Zinc finger protein 76 OS=Homo sapiens OX=9606 GN=ZNF76 PE=1 SV=2 6 2689.7 - 463432 - - - 1.5141 - 1.561 0.452 - 143.2 1 2 0 0.0017 9 0 0 0 3.48E+07 1.23E+07 - - - 3.6673 0.9997 221125_WJC_METTL3_EV_vs_WT_F02.12729.12729.2 0.0054 18-Sep K.LITPAVVSER.L sp|P62851|RS25_HUMAN 1 1083.6288 1.19 13268 12729 2 1083.628697 542.8217 40S ribosomal protein S25 OS=Homo sapiens OX=9606 GN=RPS25 PE=1 SV=1 6 2690 - 4.36E+07 - - - -0.1034 - 1.899 0.366 - 285.5 1 2 0 -0.0001 10 0 0 0 2.79E+09 2.34E+09 - - - 3.5344 0.9987 221125_WJC_METTL3_EV_vs_WT_F02.12734.12734.2 0.000394 22-Nov R.FLENVAAAETEK[136.11].Q sp|Q9Y613|FHOD1_HUMAN 1 1328.6703 1.01 13272 12734 2 1328.673449 665.3424 FH1\FH2 domain-containing protein 1 OS=Homo sapiens OX=9606 GN=FHOD1 PE=1 SV=3 4.25 2690.6 - 199965 - - - 2.3354 - 1.917 0.327 - 322.1 1 2 0 0.0031 12 0 0 0 3.61E+06 3.57E+06 - - - 3.1675 0.9999 221125_WJC_METTL3_EV_vs_WT_F02.12736.12736.2 7.25E-07 20-Nov K.LSAMMGAVAEK[136.11].K "sp|Q86U44|MTA70_HUMAN,tr|F5H6D8|F5H6D8_HUMAN,tr|H0YFV6|H0YFV6_HUMAN,tr|B4DTN4|B4DTN4_HUMAN" 4 1114.5606 0.16 13273 12736 2 1114.560595 558.2876 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 6 2690.8 - 5.24E+06 - - - -0.0063 - 2.332 0.555 - 338.3 1 2 0 0 11 0 0 0 1.17E+08 7.34E+08 - - - 5.4308 0.9586 221125_WJC_METTL3_EV_vs_WT_F02.12755.12755.2 0.0225 14-Sep L.TLVFVETK[136.11].K "sp|O00571|DDX3X_HUMAN,sp|O15523|DDX3Y_HUMAN,sp|P17844|DDX5_HUMAN,tr|A0A2R8YFR4|A0A2R8YFR4_HUMAN,tr|A0A2R8YCW1|A0A2R8YCW1_HUMAN,tr|A0A7I2V5F5|A0A7I2V5F5_HUMAN,tr|A0A2R8YDH3|A0A2R8YDH3_HUMAN,tr|A0A2R8YDT5|A0A2R8YDT5_HUMAN,tr|A0A2R8Y645|A0A2R8Y645_HUMAN,tr|A0A2R8YF78|A0A2R8YF78_HUMAN,tr|A0A0D9SFB3|A0A0D9SFB3_HUMAN,tr|A0A2R8YFS5|A0A2R8YFS5_HUMAN,tr|J3QSF1|J3QSF1_HUMAN,tr|A0A7I2V507|A0A7I2V507_HUMAN,tr|A0A0D9SF53|A0A0D9SF53_HUMAN,tr|J3KTA4|J3KTA4_HUMAN,tr|A0A0J9YVQ7|A0A0J9YVQ7_HUMAN,tr|A0A0G2JLI4|A0A0G2JLI4_HUMAN,tr|A0A2R8Y5G6|A0A2R8Y5G6_HUMAN,tr|A0A2R8Y7T2|A0A2R8Y7T2_HUMAN,tr|A0A0D9SG12|A0A0D9SG12_HUMAN,tr|A0A7I2V2S0|A0A7I2V2S0_HUMAN,tr|F6S8Q4|F6S8Q4_HUMAN,tr|A0A2U3TZJ9|A0A2U3TZJ9_HUMAN,tr|A0A2R8Y4A4|A0A2R8Y4A4_HUMAN" 25 943.547 1.67 13287 12755 2 943.546918 472.7808 ATP-dependent RNA helicase DDX3X OS=Homo sapiens OX=9606 GN=DDX3X PE=1 SV=3 5.66 2693.1 - 2.03E+06 - - - -0.0699 - 1.53 0.317 - 239 1 1 0 -0.0001 8 0 0 0 1.87E+09 1.12E+09 - - - 2.6649 0.986 221125_WJC_METTL3_EV_vs_WT_F02.12756.12756.2 0.000622 16-Sep P.PVQVSPLIK[136.11].L sp|P56385|ATP5I_HUMAN 1 987.6208 1.07 13288 12756 2 987.620385 494.8177 "ATP synthase subunit e, mitochondrial OS=Homo sapiens OX=9606 GN=ATP5ME PE=1 SV=2" 9.18 2693.2 - 1.60E+06 - - - -0.4374 - 1.575 0.478 - 239.7 1 1 0 -0.0004 9 0 0 0 2.89E+07 2.69E+07 - - - 3.8856 0.9973 221125_WJC_METTL3_EV_vs_WT_F02.12757.12757.2 0.0262 16-Sep R.LLTSGYLQR.E "sp|Q96FW1|OTUB1_HUMAN,tr|F5H3F0|F5H3F0_HUMAN,tr|F5GYN4|F5GYN4_HUMAN,tr|F5GYJ8|F5GYJ8_HUMAN,tr|J3KR44|J3KR44_HUMAN,tr|F5H6Q1|F5H6Q1_HUMAN" 6 1049.5869 0.87 13289 12757 2 1049.58718 525.8007 Ubiquitin thioesterase OTUB1 OS=Homo sapiens OX=9606 GN=OTUB1 PE=1 SV=2 8.75 2693.3 - 1.01E+06 - - - 0.2239 - 1.452 0.198 - 236.3 1 2 0 0.0002 9 0 0 0 1.97E+07 2.26E+07 - - - 1.5823 0.9938 221125_WJC_METTL3_EV_vs_WT_F02.12758.12758.2 0.0818 20-Nov K.VVDALNQGLPR.V "sp|Q14807|KIF22_HUMAN,tr|H3BRB3|H3BRB3_HUMAN" 2 1180.6564 2.39 13290 12758 2 1180.662021 591.3355 Kinesin-like protein KIF22 OS=Homo sapiens OX=9606 GN=KIF22 PE=1 SV=5 5.81 2693.4 - 340465 - - - 4.7431 - 2.099 0.308 - 273.9 1 2 0 0.0056 11 0 0 0 1.34E+07 5.60E+06 - - - 3.32 0.9994 221125_WJC_METTL3_EV_vs_WT_F02.12760.12760.2 0.223 24-Aug K.ILADAAAEGVPVR.G "sp|Q5BJH7|YIF1B_HUMAN,tr|K7EPQ7|K7EPQ7_HUMAN" 2 1280.7089 0.25 13292 12760 2 1280.70931 641.3617 Protein YIF1B OS=Homo sapiens OX=9606 GN=YIF1B PE=1 SV=1 4.37 2693.7 - 203910 - - - 0.3584 - 1.657 0.35 - 163 1 2 0 0.0005 13 0 0 0 2.20E+06 8.84E+06 - - - 2.9221 0.9997 221125_WJC_METTL3_EV_vs_WT_F02.12761.12761.2 0.000536 24-Aug K.ILADAAAEGVPVR[166.11].G "sp|Q5BJH7|YIF1B_HUMAN,tr|K7EPQ7|K7EPQ7_HUMAN" 2 1290.7171 0.12 13293 12761 2 1290.717001 646.3658 Protein YIF1B OS=Homo sapiens OX=9606 GN=YIF1B PE=1 SV=1 4.37 2693.8 - 176340 - - - -0.093 - 1.774 0.431 - 178.3 1 2 0 -0.0001 13 0 0 0 3.54E+06 2.97E+07 - - - 3.6956 0.9985 221125_WJC_METTL3_EV_vs_WT_F02.12767.12767.2 0.0228 16-Aug K.NMALSIAER.Y "sp|Q8N1F7|NUP93_HUMAN,tr|H3BRD9|H3BRD9_HUMAN,tr|H3BVG0|H3BVG0_HUMAN,tr|H3BVE2|H3BVE2_HUMAN" 4 1003.5121 2.38 13297 12767 2 1003.515043 502.7633 Nuclear pore complex protein Nup93 OS=Homo sapiens OX=9606 GN=NUP93 PE=1 SV=2 6 2694.4 - 1.93E+06 - - - 2.9676 - 1.902 0.346 - 276.5 1 2 0 0.003 9 0 0 0 6.25E+07 2.63E+07 - - - 3.4556 0.9576 221125_WJC_METTL3_EV_vs_WT_F02.12768.12768.2 2.95 14-Aug K.YIDVVINK[136.11].N "sp|O75525|KHDR3_HUMAN,tr|E5RJZ9|E5RJZ9_HUMAN,tr|E5RHD3|E5RHD3_HUMAN,tr|E5RG12|E5RG12_HUMAN" 4 970.5579 1.65 13298 12768 2 970.55783 486.2862 "KH domain-containing, RNA-binding, signal transduction-associated protein 3 OS=Homo sapiens OX=9606 GN=KHDRBS3 PE=1 SV=1" 5.83 2694.5 - 413176 - - - -0.0546 - 1.198 0.011 - 140.1 1 2 0 -0.0001 8 0 0 0 1.28E+07 7.73E+06 - - - -0.3329 0.9989 221125_WJC_METTL3_EV_vs_WT_F02.12770.12770.2 0.00273 20-Nov K.VVDALNQGLPR[166.11].V "sp|Q14807|KIF22_HUMAN,tr|H3BRB3|H3BRB3_HUMAN" 2 1190.6647 2.35 13300 12770 2 1190.660956 596.3396 Kinesin-like protein KIF22 OS=Homo sapiens OX=9606 GN=KIF22 PE=1 SV=5 5.81 2694.8 - 274144 - - - -3.1369 - 2.167 0.387 - 268.5 1 2 0 -0.0037 11 0 0 0 1.32E+07 5.60E+06 - - - 3.9903 0.9982 221125_WJC_METTL3_EV_vs_WT_F02.12776.12776.2 0.21 18-Jul K.LITPAVVSER[166.11].L sp|P62851|RS25_HUMAN 1 1093.6371 1.19 13305 12776 2 1093.637049 547.8258 40S ribosomal protein S25 OS=Homo sapiens OX=9606 GN=RPS25 PE=1 SV=1 6 2695.5 - 1.29E+07 - - - -0.0274 - 1.725 0.179 - 206.4 1 2 0 0 10 0 0 0 2.79E+09 2.34E+09 - - - 1.885 0.9726 221125_WJC_METTL3_EV_vs_WT_F02.12778.12778.2 0.476 16-Jul K.AVITPDFEK[136.11].N sp|Q5QJE6|TDIF2_HUMAN 1 1026.5477 0.17 13307 12778 2 1026.546262 514.2811 Deoxynucleotidyltransferase terminal-interacting protein 2 OS=Homo sapiens OX=9606 GN=DNTTIP2 PE=1 SV=2 4.37 2695.6 - 1.52E+06 - - - -1.4125 - 1.401 0.054 - 123.8 3 2 0 -0.0015 9 0 0 0 1.28E+07 7.57E+07 - - - 0.2018 0.9992 221125_WJC_METTL3_EV_vs_WT_F02.12782.12782.2 0.0061 14-Sep R.MALFAGGK[136.11].L "sp|Q7Z7H5|TMED4_HUMAN,tr|F8W7F7|F8W7F7_HUMAN" 2 801.4298 1.19 13311 12782 2 801.431287 401.7222 Transmembrane emp24 domain-containing protein 4 OS=Homo sapiens OX=9606 GN=TMED4 PE=1 SV=1 8.5 2696 - 592647 - - - 1.7993 - 1.878 0.309 - 317.3 1 2 0 0.0014 8 0 0 0 3.89E+06 3.26E+06 - - - 3.2235 0.9994 221125_WJC_METTL3_EV_vs_WT_F02.12787.12787.2 0.00109 16-Sep K.QFAEMYVAK[136.11].F sp|P13639|EF2_HUMAN 1 1093.5358 0.37 13314 12787 2 1093.536589 547.7752 Elongation factor 2 OS=Homo sapiens OX=9606 GN=EEF2 PE=1 SV=4 6 2696.6 - 9.95E+06 - - - 0.7517 - 1.324 0.43 - 312.8 1 2 0 0.0008 9 0 0 0 7.54E+07 2.06E+08 - - - 3.0287 0.8305 221125_WJC_METTL3_EV_vs_WT_F02.12788.12788.2 0.0907 18-Jun F.PAVFGDFLGR[166.11].E sp|Q14315|FLNC_HUMAN 1 1087.569 0.98 13315 12788 2 1087.569746 544.7918 Filamin-C OS=Homo sapiens OX=9606 GN=FLNC PE=1 SV=3 6.27 2696.6 - 9.73E+06 - - - 0.6859 - 1.474 0.186 - 167.1 1 1 0 0.0007 10 0 0 0 1.86E+09 1.91E+09 - - - 1.4975 0.9992 221125_WJC_METTL3_EV_vs_WT_F02.12791.12791.2 0.00111 18-Sep K.GFGQGSALLK.H sp|Q9NW07|ZN358_HUMAN 1 976.5342 1.17 13318 12791 2 976.534861 489.2744 Zinc finger protein 358 OS=Homo sapiens OX=9606 GN=ZNF358 PE=1 SV=2 8.75 2696.9 - 715422 - - - 0.6963 - 1.359 0.38 - 138.2 1 2 0 0.0007 10 0 0 0 1.93E+07 1.66E+07 - - - 2.7037 0.9914 221125_WJC_METTL3_EV_vs_WT_F02.12797.12797.2 0.235 16-Jul K.NMALSIAER[166.11].Y "sp|Q8N1F7|NUP93_HUMAN,tr|H3BRD9|H3BRD9_HUMAN,tr|H3BVG0|H3BVG0_HUMAN,tr|H3BVE2|H3BVE2_HUMAN" 4 1013.5203 2.48 13322 12797 2 1013.522039 507.7674 Nuclear pore complex protein Nup93 OS=Homo sapiens OX=9606 GN=NUP93 PE=1 SV=2 6 2697.7 - 1.29E+06 - - - 1.6813 - 1.533 0.121 - 158 1 2 0 0.0017 9 0 0 0 6.02E+07 2.43E+07 - - - 1.1702 0.9998 221125_WJC_METTL3_EV_vs_WT_F02.12798.12798.2 0.00119 18-Aug K.GFGQGSALLK[136.11].H sp|Q9NW07|ZN358_HUMAN 1 984.5484 1.57 13323 12798 2 984.547942 493.2815 Zinc finger protein 358 OS=Homo sapiens OX=9606 GN=ZNF358 PE=1 SV=2 8.75 2697.8 - 992870 - - - -0.4459 - 1.575 0.484 - 156.3 1 2 0 -0.0004 10 0 0 0 2.68E+07 1.71E+07 - - - 3.8837 0.9996 221125_WJC_METTL3_EV_vs_WT_F02.12804.12804.2 0.0382 18-Sep R.ILIATDVASR[166.11].G "sp|Q9Y6V7|DDX49_HUMAN,sp|Q9H0S4|DDX47_HUMAN,sp|Q92841|DDX17_HUMAN,sp|P17844|DDX5_HUMAN,tr|A0A0U1RQJ0|A0A0U1RQJ0_HUMAN,tr|A0A7I2V5F5|A0A7I2V5F5_HUMAN,tr|A0A7I2V507|A0A7I2V507_HUMAN,tr|A0A5H1ZRQ2|A0A5H1ZRQ2_HUMAN,tr|J3KTA4|J3KTA4_HUMAN,tr|A0A0G2JLI4|A0A0G2JLI4_HUMAN,tr|A0A1X7SBZ2|A0A1X7SBZ2_HUMAN,tr|A0A7I2V2S0|A0A7I2V2S0_HUMAN" 12 1067.6214 0.82 13327 12804 2 1067.622431 534.818 Probable ATP-dependent RNA helicase DDX49 OS=Homo sapiens OX=9606 GN=DDX49 PE=1 SV=1 5.84 2698.4 - 784514 - - - 0.9385 - 2.226 0.303 - 229.8 1 2 0 0.001 10 0 0 0 1.29E+07 1.58E+07 - - - 3.5123 0.9984 221125_WJC_METTL3_EV_vs_WT_F02.12806.12806.2 0.0367 18-Nov R.ILIATDVASR.G "sp|Q9Y6V7|DDX49_HUMAN,sp|Q9H0S4|DDX47_HUMAN,sp|Q92841|DDX17_HUMAN,sp|P17844|DDX5_HUMAN,tr|A0A0U1RQJ0|A0A0U1RQJ0_HUMAN,tr|A0A7I2V5F5|A0A7I2V5F5_HUMAN,tr|A0A7I2V507|A0A7I2V507_HUMAN,tr|A0A5H1ZRQ2|A0A5H1ZRQ2_HUMAN,tr|J3KTA4|J3KTA4_HUMAN,tr|A0A0G2JLI4|A0A0G2JLI4_HUMAN,tr|A0A1X7SBZ2|A0A1X7SBZ2_HUMAN,tr|A0A7I2V2S0|A0A7I2V2S0_HUMAN" 12 1057.6132 0.82 13329 12806 2 1057.616751 529.8139 Probable ATP-dependent RNA helicase DDX49 OS=Homo sapiens OX=9606 GN=DDX49 PE=1 SV=1 5.84 2698.6 - 644548 - - - 3.3963 - 2.292 0.327 - 320.8 1 2 0 0.0036 10 0 0 0 1.29E+07 1.57E+07 - - - 3.7703 0.9998 221125_WJC_METTL3_EV_vs_WT_F02.12807.12807.2 9.65E-05 14/20 K.LATNAAVTVLR[166.11].V "sp|P50990|TCPQ_HUMAN,tr|H7C2U0|H7C2U0_HUMAN" 2 1137.6745 0.38 13330 12807 2 1137.67618 569.8445 T-complex protein 1 subunit theta OS=Homo sapiens OX=9606 GN=CCT8 PE=1 SV=4 9.75 2698.8 - 395111 - - - 1.4521 - 2.357 0.431 - 847.6 1 2 0 0.0017 11 0 0 0 7.47E+08 1.94E+09 - - - 4.5433 0.973 221125_WJC_METTL3_EV_vs_WT_F02.12808.12808.2 2.87 16-Jun K.VIFPAPTPK.N "sp|Q13423|NNTM_HUMAN,tr|E9PCX7|E9PCX7_HUMAN,tr|A0A590UK15|A0A590UK15_HUMAN,tr|A0A590UJM2|A0A590UJM2_HUMAN,tr|A0A590UK29|A0A590UK29_HUMAN,tr|A0A590UJI3|A0A590UJI3_HUMAN" 6 968.5695 0.98 13331 12808 2 968.570843 485.292 "NAD(P) transhydrogenase, mitochondrial OS=Homo sapiens OX=9606 GN=NNT PE=1 SV=3" 8.72 2698.9 - 270387 - - - 1.3825 - 1.215 0.126 - 85 4 2 0 0.0013 9 0 0 0 1.95E+07 1.99E+07 - - - 0.2657 0.9995 221125_WJC_METTL3_EV_vs_WT_F02.12811.12811.2 0.00269 18-Aug K.LSLTQDPVVK[136.11].V "sp|O95757|HS74L_HUMAN,tr|E9PDE8|E9PDE8_HUMAN" 2 1106.6427 0.08 13333 12811 2 1106.643272 554.3286 Heat shock 70 kDa protein 4L OS=Homo sapiens OX=9606 GN=HSPA4L PE=1 SV=3 5.84 2699.2 - 3.63E+06 - - - 0.5395 - 1.851 0.319 - 172.2 1 2 0 0.0006 10 0 0 0 5.70E+06 7.23E+07 - - - 3.1156 0.9994 221125_WJC_METTL3_EV_vs_WT_F02.12812.12812.2 0.0306 16-Nov K.VGLQVVAVK[136.11].A "sp|P10809|CH60_HUMAN,tr|A0A7I2V2X6|A0A7I2V2X6_HUMAN,tr|A0A7I2YQK6|A0A7I2YQK6_HUMAN,tr|A0A7I2V599|A0A7I2V599_HUMAN,tr|A0A7I2V5M1|A0A7I2V5M1_HUMAN" 5 919.5946 1.21 13334 12812 2 919.595194 460.8046 "60 kDa heat shock protein, mitochondrial OS=Homo sapiens OX=9606 GN=HSPD1 PE=1 SV=2" 8.72 2699.3 - 1.19E+06 - - - 0.6427 - 2.165 0.23 - 340.9 1 2 0 0.0006 9 0 0 0 1.68E+10 1.39E+10 - - - 2.9742 0.9972 221125_WJC_METTL3_EV_vs_WT_F02.12813.12813.2 0.918 12-Jul R.LQPFLQR.Y "sp|P46379|BAG6_HUMAN,tr|A0A7I2V508|A0A7I2V508_HUMAN,tr|A0A0G2JJM1|A0A0G2JJM1_HUMAN,tr|X6REW1|X6REW1_HUMAN,tr|A0A7P0MQS5|A0A7P0MQS5_HUMAN,tr|F6S6P2|F6S6P2_HUMAN,tr|A0A0G2JL47|A0A0G2JL47_HUMAN,tr|A0A024RCR6|A0A024RCR6_HUMAN,tr|A0A0G2JK23|A0A0G2JK23_HUMAN" 9 900.5181 1.67 13335 12813 2 900.518643 451.2663 Large proline-rich protein BAG6 OS=Homo sapiens OX=9606 GN=BAG6 PE=1 SV=2 9.75 2699.3 - 7.23E+06 - - - 0.5619 - 1.565 0.157 - 189.4 1 2 0 0.0005 7 0 0 0 1.80E+08 1.08E+08 - - - 1.6196 0.9987 221125_WJC_METTL3_EV_vs_WT_F02.12815.12815.2 0.203 16-Sep K.AIAALISEK[136.11].L "sp|Q8IXB1|DJC10_HUMAN,tr|A0A7P0Z431|A0A7P0Z431_HUMAN,tr|A0A7P0TB97|A0A7P0TB97_HUMAN,tr|A0A7P0TAQ9|A0A7P0TAQ9_HUMAN" 4 922.5579 0.59 13337 12815 2 922.559121 462.2862 DnaJ homolog subfamily C member 10 OS=Homo sapiens OX=9606 GN=DNAJC10 PE=1 SV=2 6.05 2699.4 - 1.47E+06 - - - 1.3419 - 2.012 0.216 - 195.8 2 2 0 0.0012 9 0 0 0 6.58E+07 1.12E+08 - - - 2.5241 0.8094 221125_WJC_METTL3_EV_vs_WT_F02.12816.12816.2 2.16 16-Jun R.FAVAPDFLK[136.11].F sp|Q9ULS6|KCNS2_HUMAN 1 1014.563 0.32 13338 12816 2 1014.566033 508.2888 Potassium voltage-gated channel subfamily S member 2 OS=Homo sapiens OX=9606 GN=KCNS2 PE=1 SV=2 5.84 2699.5 - 1.17E+06 - - - 3.021 - 1.179 0.028 - 119.9 2 2 0 0.0031 9 0 0 0 9.66E+06 3.03E+07 - - - -0.4112 0.9929 221125_WJC_METTL3_EV_vs_WT_F02.12817.12817.2 4.33E-05 20-Nov K.VLVLGDSGVGK[136.11].S "sp|Q5HYI8|RABL3_HUMAN,tr|H7C533|H7C533_HUMAN,tr|F8WAX9|F8WAX9_HUMAN,tr|F8WF50|F8WF50_HUMAN,tr|C9JXM3|C9JXM3_HUMAN,tr|F8WDC7|F8WDC7_HUMAN" 6 1050.6165 2.06 13339 12817 2 1050.622854 526.3155 Rab-like protein 3 OS=Homo sapiens OX=9606 GN=RABL3 PE=1 SV=1 5.81 2699.6 - 618021 - - - 6.086 - 2.184 0.424 - 308.4 1 2 0 0.0064 11 0 0 0 8.28E+07 4.01E+07 - - - 4.2839 0.999 221125_WJC_METTL3_EV_vs_WT_F02.12822.12822.2 0.458 20-Sep K.IIVIGDSNVGK[136.11].T "sp|Q9H082|RB33B_HUMAN,sp|Q14088|RB33A_HUMAN,tr|A0A494C0Z5|A0A494C0Z5_HUMAN" 3 1121.6536 1.06 13342 12822 2 1121.651988 561.8341 Ras-related protein Rab-33B OS=Homo sapiens OX=9606 GN=RAB33B PE=1 SV=1 5.84 2700.2 - 317376 - - - -1.414 - 1.785 0.293 - 159.7 1 2 0 -0.0016 11 0 0 0 1.10E+07 1.03E+07 - - - 2.7721 0.9999 221125_WJC_METTL3_EV_vs_WT_F02.12824.12824.2 0.000123 14/20 K.LATNAAVTVLR.V "sp|P50990|TCPQ_HUMAN,tr|H7C2U0|H7C2U0_HUMAN" 2 1127.6663 0.38 13344 12824 2 1127.666975 564.8404 T-complex protein 1 subunit theta OS=Homo sapiens OX=9606 GN=CCT8 PE=1 SV=4 9.75 2700.4 - 720891 - - - 0.6358 - 2.629 0.491 - 836 1 2 0 0.0007 11 0 0 0 7.47E+08 1.94E+09 - - - 5.2822 0.9948 221125_WJC_METTL3_EV_vs_WT_F02.12830.12830.2 0.0578 16-Aug K.IAPYSVEIK[136.11].N "sp|P78527|PRKDC_HUMAN,tr|F5GX40|F5GX40_HUMAN" 2 1026.5841 2.5 13348 12830 2 1026.587561 514.2993 DNA-dependent protein kinase catalytic subunit OS=Homo sapiens OX=9606 GN=PRKDC PE=1 SV=3 6 2701.2 - 1.04E+06 - - - 3.3733 - 1.532 0.3 - 186.4 1 2 0 0.0035 9 0 0 0 6.04E+07 2.42E+07 - - - 2.4898 0.9979 221125_WJC_METTL3_EV_vs_WT_F02.12831.12831.2 0.0102 20-Sep R.LIIAGTSAYAR[166.11].L "sp|P34897|GLYM_HUMAN,tr|H0YIZ0|H0YIZ0_HUMAN,tr|G3V5L0|G3V5L0_HUMAN,tr|G3V2Y4|G3V2Y4_HUMAN" 4 1144.648 0.44 13349 12831 2 1144.650042 573.3313 "Serine hydroxymethyltransferase, mitochondrial OS=Homo sapiens OX=9606 GN=SHMT2 PE=1 SV=3" 8.75 2701.3 - 709041 - - - 1.8032 - 1.652 0.265 - 223.1 1 2 0 0.0021 11 0 0 0 1.40E+07 3.19E+07 - - - 2.3556 1 221125_WJC_METTL3_EV_vs_WT_F02.12837.12837.3 1.99E-11 21/84 K.DHTPSQELALTQSVGGDSSADR[166.11].L "sp|Q86U44|MTA70_HUMAN,tr|H0YFV6|H0YFV6_HUMAN" 2 2280.0494 0.001 13353 12837 3 2280.048787 761.0237 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 4.22 2702 - 624775 - - - -0.2544 - 3.697 0.68 - 429.7 1 2 0 -0.0006 22 0 0 0 0.00E+00 1.23E+07 - - - 9.2211 0.9988 221125_WJC_METTL3_EV_vs_WT_F02.12838.12838.2 0.0132 12-May R.ELFYEDR.H sp|Q13643|FHL3_HUMAN 1 970.4396 1.5 13354 12838 2 970.438426 486.2271 Four and a half LIM domains protein 3 OS=Homo sapiens OX=9606 GN=FHL3 PE=1 SV=4 4.14 2702.2 - 548450 - - - -1.2221 - 1.294 0.356 - 111.3 1 2 0 -0.0012 7 0 0 0 4.39E+07 2.94E+07 - - - 2.4867 0.9979 221125_WJC_METTL3_EV_vs_WT_F02.12839.12839.2 0.272 16-Oct K.AIAALISEK.L "sp|Q8IXB1|DJC10_HUMAN,tr|A0A7P0Z431|A0A7P0Z431_HUMAN,tr|A0A7P0TB97|A0A7P0TB97_HUMAN,tr|A0A7P0TAQ9|A0A7P0TAQ9_HUMAN" 4 914.5437 0.59 13355 12839 2 914.546129 458.2791 DnaJ homolog subfamily C member 10 OS=Homo sapiens OX=9606 GN=DNAJC10 PE=1 SV=2 6.05 2702.2 - 2.65E+06 - - - 2.6746 - 1.841 0.28 - 287.9 1 2 0 0.0024 9 0 0 0 6.58E+07 1.12E+08 - - - 2.874 0.9994 221125_WJC_METTL3_EV_vs_WT_F02.12840.12840.2 0.0424 14-Oct K.LQGEFQLR.L "sp|Q14204|DYHC1_HUMAN,tr|A0A7P0T8N2|A0A7P0T8N2_HUMAN,tr|A0A7P0T9C4|A0A7P0T9C4_HUMAN,tr|A0A7P0TBJ7|A0A7P0TBJ7_HUMAN,tr|A0A7P0T9K2|A0A7P0T9K2_HUMAN,tr|A0A2R8Y706|A0A2R8Y706_HUMAN,tr|A0A7P0T916|A0A7P0T916_HUMAN,tr|A0A7P0TB75|A0A7P0TB75_HUMAN,tr|A0A7P0TAF3|A0A7P0TAF3_HUMAN,tr|A0A7P0TAW9|A0A7P0TAW9_HUMAN,tr|A0A7P0TA13|A0A7P0TA13_HUMAN,tr|A0A7P0T7V5|A0A7P0T7V5_HUMAN,tr|A0A7P0T9R4|A0A7P0T9R4_HUMAN,tr|A0A2R8Y5T0|A0A2R8Y5T0_HUMAN,tr|A0A2R8Y6H2|A0A2R8Y6H2_HUMAN" 15 989.5294 0.93 13356 12840 2 989.529741 495.772 Cytoplasmic dynein 1 heavy chain 1 OS=Homo sapiens OX=9606 GN=DYNC1H1 PE=1 SV=5 6 2702.3 - 1.71E+06 - - - 0.3143 - 1.906 0.265 - 280.5 1 2 0 0.0003 8 0 0 0 5.44E+07 5.87E+07 - - - 2.9435 0.9549 221125_WJC_METTL3_EV_vs_WT_F02.12841.12841.2 3.15 12-Jun R.NLINLGK[136.11].N sp|Q9UHR4|BI2L1_HUMAN 1 778.4792 1.51 13357 12841 2 778.479559 390.2469 Brain-specific angiogenesis inhibitor 1-associated protein 2-like protein 1 OS=Homo sapiens OX=9606 GN=BAIAP2L1 PE=1 SV=2 8.75 2702.4 - 428501 - - - 0.4123 - 1.211 0.003 - 113.9 1 2 0 0.0003 7 0 0 0 7.96E+06 5.26E+06 - - - -0.3303 0.9986 221125_WJC_METTL3_EV_vs_WT_F02.12847.12847.2 0.0119 12-Jun R.ELFYEDR[166.11].H sp|Q13643|FHL3_HUMAN 1 980.4479 1.57 13361 12847 2 980.445383 491.2312 Four and a half LIM domains protein 3 OS=Homo sapiens OX=9606 GN=FHL3 PE=1 SV=4 4.14 2703.1 - 1.01E+06 - - - -2.5488 - 1.479 0.386 - 148.2 1 2 0 -0.0025 7 0 0 0 3.88E+07 2.46E+07 - - - 3.1313 0.9914 221125_WJC_METTL3_EV_vs_WT_F02.12850.12850.2 0.469 14-Jun K.LLSSYLQK[136.11].K "sp|P23919|KTHY_HUMAN,tr|H7BZ20|H7BZ20_HUMAN,tr|H7C312|H7C312_HUMAN,tr|G5E9E9|G5E9E9_HUMAN,tr|H7C3A4|H7C3A4_HUMAN" 5 958.5579 1.98 13362 12850 2 958.55897 480.2862 Thymidylate kinase OS=Homo sapiens OX=9606 GN=DTYMK PE=1 SV=4 8.59 2703.5 - 1.37E+06 - - - 1.134 - 1.007 0.257 - 60.5 1 2 0 0.0011 8 0 0 0 3.99E+07 2.01E+07 - - - 0.9599 0.9958 221125_WJC_METTL3_EV_vs_WT_F02.12851.12851.2 0.521 18-Oct K.AVILIGGPQK.G "sp|Q96IJ6|GMPPA_HUMAN,tr|B4DJR0|B4DJR0_HUMAN,tr|A0A804HIM4|A0A804HIM4_HUMAN,tr|A0A804HIS0|A0A804HIS0_HUMAN,tr|F8WD54|F8WD54_HUMAN,tr|C9J255|C9J255_HUMAN,tr|A0A804HLK2|A0A804HLK2_HUMAN,tr|A0A804HJC3|A0A804HJC3_HUMAN,tr|A0A087WUI8|A0A087WUI8_HUMAN,tr|A0A804HLB2|A0A804HLB2_HUMAN,tr|A0A804HKA4|A0A804HKA4_HUMAN" 11 994.6175 0.65 13363 12851 2 994.615105 498.316 Mannose-1-phosphate guanyltransferase alpha OS=Homo sapiens OX=9606 GN=GMPPA PE=1 SV=1 8.8 2703.6 - 317763 - - - -2.424 - 2.07 0.133 - 278.6 1 2 0 -0.0024 10 0 0 0 6.00E+07 9.28E+07 - - - 2.0534 0.9999 221125_WJC_METTL3_EV_vs_WT_F02.12852.12852.2 1.92E-05 22-Dec K.AYLEEEC[160.03]PATLR.K "sp|P25311|ZA2G_HUMAN,tr|C9JEV0|C9JEV0_HUMAN" 2 1450.6762 999 13364 12852 2 1450.677434 726.3454 Zinc-alpha-2-glycoprotein OS=Homo sapiens OX=9606 GN=AZGP1 PE=1 SV=2 4.25 2703.7 - 627824 - - - 0.83 - 2.639 0.496 - 568.5 1 2 0 0.0012 12 0 0 0 1.83E+07 0.00E+00 - - - 5.2574 0.9995 221125_WJC_METTL3_EV_vs_WT_F02.12854.12854.2 0.0163 16-Sep K.IEQAMDLVK.S "sp|Q15714|T22D1_HUMAN,sp|Q9Y3Q8|T22D4_HUMAN,sp|Q99576|T22D3_HUMAN,sp|O75157|T22D2_HUMAN,tr|Q5JRJ0|Q5JRJ0_HUMAN,tr|H7BZ77|H7BZ77_HUMAN,tr|H0Y865|H0Y865_HUMAN,tr|E7EWD5|E7EWD5_HUMAN" 8 1045.5478 1.53 13365 12854 2 1045.548822 523.7812 TSC22 domain family protein 1 OS=Homo sapiens OX=9606 GN=TSC22D1 PE=1 SV=3 4.37 2704 - 1.99E+06 - - - 0.9947 - 1.863 0.346 - 176 1 2 0 0.001 9 0 0 0 5.72E+07 3.75E+07 - - - 3.3963 0.9985 221125_WJC_METTL3_EV_vs_WT_F02.12861.12861.2 0.146 22-Jul R.VLEVETTPGSLR.N "sp|Q9NXL9|MCM9_HUMAN,tr|H0Y6M9|H0Y6M9_HUMAN" 2 1299.7034 0.56 13368 12861 2 1299.705287 650.859 DNA helicase MCM9 OS=Homo sapiens OX=9606 GN=MCM9 PE=1 SV=4 4.53 2704.9 - 129278 - - - 1.428 - 1.719 0.267 - 189.5 1 2 0 0.0019 12 0 0 0 2.74E+06 4.90E+06 - - - 2.4379 0.9994 221125_WJC_METTL3_EV_vs_WT_F02.12863.12863.2 0.0249 14-Aug R.TFGVSPLR.R sp|Q5T750|XP32_HUMAN 1 875.4865 11.13 13369 12863 2 875.48581 438.7505 Skin-specific protein 32 OS=Homo sapiens OX=9606 GN=XP32 PE=1 SV=1 9.41 2705.1 - 2.21E+06 - - - -0.7904 - 1.584 0.351 - 221.4 1 2 0 -0.0007 8 0 0 0 3.17E+08 2.85E+07 - - - 3.0205 0.9998 221125_WJC_METTL3_EV_vs_WT_F02.12865.12865.2 0.00277 20-Oct K.VLVLGDSGVGK.S "sp|Q5HYI8|RABL3_HUMAN,tr|H7C533|H7C533_HUMAN,tr|F8WAX9|F8WAX9_HUMAN,tr|F8WF50|F8WF50_HUMAN,tr|C9JXM3|C9JXM3_HUMAN,tr|F8WDC7|F8WDC7_HUMAN" 6 1042.6023 1.65 13371 12865 2 1042.601929 522.3084 Rab-like protein 3 OS=Homo sapiens OX=9606 GN=RABL3 PE=1 SV=1 5.81 2705.2 - 2.19E+06 - - - -0.3175 - 2.077 0.435 - 322.5 1 2 0 -0.0003 11 0 0 0 6.44E+07 3.90E+07 - - - 4.2311 0.9993 221125_WJC_METTL3_EV_vs_WT_F02.12872.12872.2 0.00229 18-Oct K.QLVTNAC[160.03]LIK[136.11].E "sp|Q99873|ANM1_HUMAN,tr|E9PKG1|E9PKG1_HUMAN,tr|E9PIX6|E9PIX6_HUMAN" 3 1166.6573 1.98 13376 12872 2 1166.655699 584.3359 Protein arginine N-methyltransferase 1 OS=Homo sapiens OX=9606 GN=PRMT1 PE=1 SV=3 8.22 2706.1 - 464903 - - - -1.3552 - 1.935 0.286 - 321.9 1 2 0 -0.0016 10 0 0 0 3.94E+08 1.99E+08 - - - 2.9955 0.9994 221125_WJC_METTL3_EV_vs_WT_F02.12874.12874.2 0.00209 20-Sep K.SLTANPELIDR[166.11].L "sp|Q9Y2L1|RRP44_HUMAN,tr|F2Z2C0|F2Z2C0_HUMAN,tr|G3V1J5|G3V1J5_HUMAN" 3 1237.6542 1.78 13378 12874 2 1237.651676 619.8344 Exosome complex exonuclease RRP44 OS=Homo sapiens OX=9606 GN=DIS3 PE=1 SV=2 4.37 2706.3 - 195266 - - - -2.028 - 1.797 0.424 - 264.6 1 2 0 -0.0025 11 0 0 0 2.58E+08 1.45E+08 - - - 3.7575 0.9993 221125_WJC_METTL3_EV_vs_WT_F02.12875.12875.2 0.0065 22-Oct R.VLEVETTPGSLR[166.11].N "sp|Q9NXL9|MCM9_HUMAN,tr|H0Y6M9|H0Y6M9_HUMAN" 2 1309.7117 0.56 13379 12875 2 1309.709357 655.8631 DNA helicase MCM9 OS=Homo sapiens OX=9606 GN=MCM9 PE=1 SV=4 4.53 2706.4 - 168867 - - - -1.7897 - 2.028 0.323 - 325.8 1 2 0 -0.0023 12 0 0 0 2.74E+06 4.90E+06 - - - 3.2863 0.9953 221125_WJC_METTL3_EV_vs_WT_F02.12877.12877.2 0.259 12-Jun K.DLEIQMK[136.11].K "sp|Q9NP61|ARFG3_HUMAN,tr|H0Y6A0|H0Y6A0_HUMAN" 2 883.4565 0.97 13380 12877 2 883.45561 442.7355 ADP-ribosylation factor GTPase-activating protein 3 OS=Homo sapiens OX=9606 GN=ARFGAP3 PE=1 SV=1 4.37 2706.7 - 2.69E+06 - - - -0.9553 - 1.247 0.207 - 123.4 1 2 0 -0.0008 7 0 0 0 9.40E+07 9.72E+07 - - - 1.2691 0.9906 221125_WJC_METTL3_EV_vs_WT_F02.12880.12880.2 0.0505 16-Jul K.AELDGTILK[136.11].S "sp|Q8WXF1|PSPC1_HUMAN,tr|X6RDA4|X6RDA4_HUMAN" 2 966.5477 1.27 13381 12880 2 966.548994 484.2811 Paraspeckle component 1 OS=Homo sapiens OX=9606 GN=PSPC1 PE=1 SV=1 4.37 2707.1 - 1.66E+06 - - - 1.3264 - 1.499 0.102 - 160.4 1 2 0 0.0013 9 0 0 0 8.42E+07 6.65E+07 - - - 0.9651 0.8908 221125_WJC_METTL3_EV_vs_WT_F02.12882.12882.2 0.498 12-May R.EVIDFAR[166.11].R "sp|Q8N983|RM43_HUMAN,tr|B1AL05|B1AL05_HUMAN,tr|H0YBU8|H0YBU8_HUMAN,tr|H0Y6Y8|H0Y6Y8_HUMAN" 4 858.4475 0.59 13383 12882 2 858.444101 430.231 "39S ribosomal protein L43, mitochondrial OS=Homo sapiens OX=9606 GN=MRPL43 PE=1 SV=1" 4.37 2707.2 - 1.04E+06 - - - -3.9455 - 1.16 0.123 - 71.9 1 2 0 -0.0034 7 0 0 0 3.17E+07 5.35E+07 - - - 0.4187 0.9997 221125_WJC_METTL3_EV_vs_WT_F02.12884.12884.2 0.000349 18-Aug K.YLNQDYEALR.N sp|P17655|CAN2_HUMAN 1 1283.6146 1.64 13385 12884 2 1283.614394 642.8146 Calpain-2 catalytic subunit OS=Homo sapiens OX=9606 GN=CAPN2 PE=1 SV=6 4.37 2707.4 - 205073 - - - -0.1729 - 1.579 0.44 - 198.2 1 2 0 -0.0002 10 0 0 0 2.32E+07 1.41E+07 - - - 3.5658 0.9994 221125_WJC_METTL3_EV_vs_WT_F02.12887.12887.2 0.199 18-Sep K.AVILIGGPQK[136.11].G "sp|Q96IJ6|GMPPA_HUMAN,tr|B4DJR0|B4DJR0_HUMAN,tr|A0A804HIM4|A0A804HIM4_HUMAN,tr|A0A804HIS0|A0A804HIS0_HUMAN,tr|F8WD54|F8WD54_HUMAN,tr|C9J255|C9J255_HUMAN,tr|A0A804HLK2|A0A804HLK2_HUMAN,tr|A0A804HJC3|A0A804HJC3_HUMAN,tr|A0A087WUI8|A0A087WUI8_HUMAN,tr|A0A804HLB2|A0A804HLB2_HUMAN,tr|A0A804HKA4|A0A804HKA4_HUMAN" 11 1002.6317 0.65 13386 12887 2 1002.631296 502.3231 Mannose-1-phosphate guanyltransferase alpha OS=Homo sapiens OX=9606 GN=GMPPA PE=1 SV=1 8.8 2707.8 - 2.27E+06 - - - -0.4189 - 1.979 0.261 - 299.7 1 2 0 -0.0004 10 0 0 0 6.00E+07 9.28E+07 - - - 2.8739 0.9998 221125_WJC_METTL3_EV_vs_WT_F02.12892.12892.2 9.71E-07 20-Nov R.ELGSSVALYSR[166.11].K "sp|Q12931|TRAP1_HUMAN,tr|I3L0K7|I3L0K7_HUMAN,tr|I3L239|I3L239_HUMAN" 3 1190.6171 2.22 13391 12892 2 1190.614907 596.3158 "Heat shock protein 75 kDa, mitochondrial OS=Homo sapiens OX=9606 GN=TRAP1 PE=1 SV=3" 6.1 2708.4 - 151730 - - - -1.8184 - 2.188 0.494 - 331.5 1 2 0 -0.0022 11 0 0 0 2.03E+08 9.13E+07 - - - 4.8072 0.9997 221125_WJC_METTL3_EV_vs_WT_F02.12895.12895.2 0.00406 14-Sep R.LAAQFIPK.F "sp|Q9BZZ5|API5_HUMAN,tr|E9PQK6|E9PQK6_HUMAN,tr|G3V1C3|G3V1C3_HUMAN" 3 886.5276 2.68 13392 12895 2 886.527712 444.2711 Apoptosis inhibitor 5 OS=Homo sapiens OX=9606 GN=API5 PE=1 SV=3 8.75 2708.8 - 3.89E+06 - - - 0.0823 - 1.699 0.394 - 215.9 1 2 0 0.0001 8 0 0 0 2.41E+08 8.99E+07 - - - 3.5496 0.9999 221125_WJC_METTL3_EV_vs_WT_F02.12896.12896.2 0.000451 20-Nov K.SLTANPELIDR.L "sp|Q9Y2L1|RRP44_HUMAN,tr|F2Z2C0|F2Z2C0_HUMAN,tr|G3V1J5|G3V1J5_HUMAN" 3 1227.6459 1.78 13393 12896 2 1227.645748 614.8302 Exosome complex exonuclease RRP44 OS=Homo sapiens OX=9606 GN=DIS3 PE=1 SV=2 4.37 2708.8 - 2.02E+06 - - - -0.1368 - 2.259 0.482 - 511.9 1 2 0 -0.0002 11 0 0 0 2.58E+08 1.45E+08 - - - 4.8056 0.9996 221125_WJC_METTL3_EV_vs_WT_F02.12901.12901.2 0.00881 20-Dec K.ALYESELADAR[166.11].R sp|Q03252|LMNB2_HUMAN 1 1246.6069 1.32 13396 12901 2 1246.607626 624.3107 Lamin-B2 OS=Homo sapiens OX=9606 GN=LMNB2 PE=1 SV=4 4.14 2709.4 - 681305 - - - 0.5808 - 1.712 0.385 - 453.1 1 2 0 0.0007 11 0 0 0 9.42E+07 7.15E+07 - - - 3.3389 0.996 221125_WJC_METTL3_EV_vs_WT_F02.12903.12903.2 0.135 14-Jul R.TWLEPAPR.G sp|P17482|HXB9_HUMAN 1 968.508 0.88 13398 12903 2 968.509333 485.2613 Homeobox protein Hox-B9 OS=Homo sapiens OX=9606 GN=HOXB9 PE=1 SV=2 5.66 2709.5 - 2.57E+06 - - - 1.4114 - 1.302 0.243 - 254.3 1 2 0 0.0014 8 0 0 0 6.19E+07 7.07E+07 - - - 1.6313 0.9997 221125_WJC_METTL3_EV_vs_WT_F02.12904.12904.2 0.000245 20-Nov R.ELGSSVALYSR.K "sp|Q12931|TRAP1_HUMAN,tr|I3L0K7|I3L0K7_HUMAN,tr|I3L239|I3L239_HUMAN" 3 1180.6088 2.22 13399 12904 2 1180.607721 591.3117 "Heat shock protein 75 kDa, mitochondrial OS=Homo sapiens OX=9606 GN=TRAP1 PE=1 SV=3" 6.1 2709.6 - 606484 - - - -0.9156 - 2.07 0.394 - 466.9 1 2 0 -0.0011 11 0 0 0 2.03E+08 9.13E+07 - - - 3.9189 0.9994 221125_WJC_METTL3_EV_vs_WT_F02.12910.12910.2 0.801 16-Jul R.IVLQIDNAR.L "sp|P05783|K1C18_HUMAN,sp|P08727|K1C19_HUMAN,tr|F8VZY9|F8VZY9_HUMAN,tr|C9JM50|C9JM50_HUMAN" 4 1040.5978 1.98 13403 12910 2 1040.596774 521.3062 "Keratin, type I cytoskeletal 18 OS=Homo sapiens OX=9606 GN=KRT18 PE=1 SV=2" 5.84 2710.5 - 3.11E+06 - - - -1.0283 - 1.655 0.342 - 142.4 1 2 0 -0.0011 9 0 0 0 3.27E+08 1.66E+08 - - - 3.0242 0.9997 221125_WJC_METTL3_EV_vs_WT_F02.12911.12911.2 0.0122 18-Sep K.YLNQDYEALR[166.11].N sp|P17655|CAN2_HUMAN 1 1293.6229 1.64 13404 12911 2 1293.623745 647.8187 Calpain-2 catalytic subunit OS=Homo sapiens OX=9606 GN=CAPN2 PE=1 SV=6 4.37 2710.6 - 808422 - - - 0.664 - 1.682 0.447 - 209.2 1 2 0 0.0009 10 0 0 0 2.32E+07 1.41E+07 - - - 3.7937 0.997 221125_WJC_METTL3_EV_vs_WT_F02.12912.12912.2 0.0323 12-Jun R.YPNLQLR.E "sp|Q14671|PUM1_HUMAN,tr|Q5T1Z8|Q5T1Z8_HUMAN,tr|H0YDK8|H0YDK8_HUMAN,tr|H0YEH2|H0YEH2_HUMAN,tr|Q5T1Z4|Q5T1Z4_HUMAN,tr|E9PR38|E9PR38_HUMAN" 6 902.4974 2.03 13405 12912 2 902.495989 452.256 Pumilio homolog 1 OS=Homo sapiens OX=9606 GN=PUM1 PE=1 SV=3 8.75 2710.7 - 1.79E+06 - - - -1.5645 - 1.211 0.298 - 115.9 1 2 0 -0.0014 7 0 0 0 8.36E+07 4.12E+07 - - - 1.8482 0.9875 221125_WJC_METTL3_EV_vs_WT_F02.12913.12913.2 0.406 12-May R.LPYEQWK.A "sp|Q16875|F263_HUMAN,tr|A0A1W2PR17|A0A1W2PR17_HUMAN,tr|Q5W015|Q5W015_HUMAN,tr|F2Z2I2|F2Z2I2_HUMAN,tr|H0Y483|H0Y483_HUMAN,tr|Q5VX20|Q5VX20_HUMAN" 6 962.4862 3.29 13406 12913 2 962.487056 482.2504 "6-phosphofructo-2-kinase\fructose-2,6-bisphosphatase 3 OS=Homo sapiens OX=9606 GN=PFKFB3 PE=1 SV=1" 6 2710.7 - 1.33E+06 - - - 0.9226 - 1.213 0.151 - 60 2 2 0 0.0009 7 0 0 0 4.11E+08 1.25E+08 - - - 0.6334 0.9998 221125_WJC_METTL3_EV_vs_WT_F02.12916.12916.2 9.07E-05 20-Oct R.LMSNALSTVTR[166.11].G "sp|Q9NZJ7|MTCH1_HUMAN,tr|H0Y8C3|H0Y8C3_HUMAN" 2 1201.6364 0.85 13409 12916 2 1201.636051 601.8255 Mitochondrial carrier homolog 1 OS=Homo sapiens OX=9606 GN=MTCH1 PE=1 SV=1 9.75 2711 - 403989 - - - -0.3137 - 1.843 0.461 - 301.3 1 2 0 -0.0004 11 0 0 0 5.60E+06 6.59E+06 - - - 4.0998 0.9998 221125_WJC_METTL3_EV_vs_WT_F02.12919.12919.2 3.63E-05 18-Oct R.DGFGGLAAAR[166.11].G sp|Q96I24|FUBP3_HUMAN 1 943.4751 1.89 13410 12919 2 943.474721 472.7448 Far upstream element-binding protein 3 OS=Homo sapiens OX=9606 GN=FUBP3 PE=1 SV=2 5.84 2711.4 - 1.28E+07 - - - -0.4006 - 1.998 0.474 - 234.4 1 2 0 -0.0004 10 0 0 0 2.26E+09 1.19E+09 - - - 4.4738 0.9959 221125_WJC_METTL3_EV_vs_WT_F02.12921.12921.2 0.00149 16-Aug K.DMGTVVLGK[136.11].L "sp|Q8IYD1|ERF3B_HUMAN,sp|P15170|ERF3A_HUMAN,tr|H3BR35|H3BR35_HUMAN" 3 926.4987 1.55 13412 12921 2 926.498949 464.2566 Eukaryotic peptide chain release factor GTP-binding subunit ERF3B OS=Homo sapiens OX=9606 GN=GSPT2 PE=1 SV=2 5.84 2711.6 - 911263 - - - 0.3195 - 1.409 0.169 - 179.2 1 2 0 0.0003 9 0 0 0 6.90E+07 4.46E+07 - - - 1.2811 0.9998 221125_WJC_METTL3_EV_vs_WT_F02.12922.12922.2 0.00516 20-Dec K.LLTDGYAC[160.03]EVR[166.11].C sp|O15226|NKRF_HUMAN 1 1305.6263 1.11 13413 12922 2 1305.626004 653.8204 NF-kappa-B-repressing factor OS=Homo sapiens OX=9606 GN=NKRF PE=1 SV=2 4.37 2711.7 - 640959 - - - -0.1938 - 2.306 0.416 - 557.3 1 2 0 -0.0003 11 0 0 0 5.95E+07 5.35E+07 - - - 4.3738 0.9997 221125_WJC_METTL3_EV_vs_WT_F02.12925.12925.2 0.0547 20-Nov K.LGQALTEVYAK[136.11].A "sp|Q00341|VIGLN_HUMAN,tr|A0A024R4E5|A0A024R4E5_HUMAN,tr|H7C0A4|H7C0A4_HUMAN" 3 1199.6641 0.91 13414 12925 2 1199.662244 600.8393 Vigilin OS=Homo sapiens OX=9606 GN=HDLBP PE=1 SV=2 6 2712.1 - 653903 - - - -1.5796 - 2.321 0.362 - 326.9 1 2 0 -0.0019 11 0 0 0 1.27E+08 1.40E+08 - - - 3.9919 0.9815 221125_WJC_METTL3_EV_vs_WT_F02.12928.12928.2 0.201 18-Aug K.VPAIYGVDTR[166.11].M "sp|P31327|CPSM_HUMAN,tr|Q5R211|Q5R211_HUMAN" 2 1099.5901 17.8 13417 12928 2 1099.59426 550.8023 "Carbamoyl-phosphate synthase [ammonia], mitochondrial OS=Homo sapiens OX=9606 GN=CPS1 PE=1 SV=2" 5.81 2712.4 - 1.26E+06 - - - 3.7569 - 1.544 0.191 - 211.2 1 2 0 0.0041 10 0 0 0 6.26E+08 3.52E+07 - - - 1.6629 0.9387 221125_WJC_METTL3_EV_vs_WT_F02.12929.12929.2 1.41 16-Jun K.VVVPPLPGK[136.11].A sp|O60493|SNX3_HUMAN 1 912.5888 0.67 13418 12929 2 912.586044 457.3017 Sorting nexin-3 OS=Homo sapiens OX=9606 GN=SNX3 PE=1 SV=3 8.72 2712.4 - 1.26E+06 - - - -3.0079 - 1.224 0.131 - 94.5 3 2 0 -0.0027 9 0 0 0 4.19E+07 6.22E+07 - - - 0.3793 0.8688 221125_WJC_METTL3_EV_vs_WT_F02.12930.12930.2 2.8 16-Jun K.DMGTVVLGK.L "sp|Q8IYD1|ERF3B_HUMAN,sp|P15170|ERF3A_HUMAN,tr|H3BR35|H3BR35_HUMAN" 3 918.4845 1.83 13419 12930 2 918.484751 460.2495 Eukaryotic peptide chain release factor GTP-binding subunit ERF3B OS=Homo sapiens OX=9606 GN=GSPT2 PE=1 SV=2 5.84 2712.5 - 1.16E+06 - - - 0.3244 - 1.037 0.001 - 90.9 3 2 0 0.0003 9 0 0 0 8.46E+07 4.62E+07 - - - -1.0597 0.9393 221125_WJC_METTL3_EV_vs_WT_F02.12937.12937.2 0.0443 16-Sep H.LLDPDVVAR[166.11].F sp|Q86U44|MTA70_HUMAN 1 1006.5687 0.01 13424 12937 2 1006.566128 504.2916 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 4.21 2713.4 - 1.61E+06 - - - -2.5204 - 1.696 0.387 - 225.7 1 1 0 -0.0025 9 0 0 0 3.57E+06 3.07E+08 - - - 3.4269 0.9999 221125_WJC_METTL3_EV_vs_WT_F02.12938.12938.2 5.39E-08 Nov-32 R.ISIGGGSC[160.03]AISGGYGSR.A "sp|P48668|K2C6C_HUMAN,sp|P04259|K2C6B_HUMAN,sp|P02538|K2C6A_HUMAN" 3 1597.7519 999 13425 12938 2 1597.752388 799.8832 "Keratin, type II cytoskeletal 6C OS=Homo sapiens OX=9606 GN=KRT6C PE=1 SV=3" 8.22 2713.5 - 170860 - - - 0.3336 - 2.075 0.639 - 281 1 2 0 0.0005 17 0 0 0 5.35E+06 0.00E+00 - - - 5.5551 0.9995 221125_WJC_METTL3_EV_vs_WT_F02.12943.12943.2 0.0108 16-Aug R.EGLGLDVER[166.11].V sp|O15226|NKRF_HUMAN 1 996.5115 1.06 13427 12943 2 996.511304 499.263 NF-kappa-B-repressing factor OS=Homo sapiens OX=9606 GN=NKRF PE=1 SV=2 4.14 2714.1 - 2.28E+06 - - - -0.2418 - 1.717 0.326 - 207.3 1 2 0 -0.0002 9 0 0 0 1.01E+08 9.56E+07 - - - 3.0127 0.9885 221125_WJC_METTL3_EV_vs_WT_F02.12945.12945.2 0.756 16-Jul K.AGLLQPPVR.L "sp|Q8IX12|CCAR1_HUMAN,tr|F5H2E6|F5H2E6_HUMAN,tr|F5H1H2|F5H1H2_HUMAN,tr|A0A0C4DGG8|A0A0C4DGG8_HUMAN,tr|F5H3E1|F5H3E1_HUMAN" 5 949.5709 4.55 13428 12945 2 949.569572 475.7927 Cell division cycle and apoptosis regulator protein 1 OS=Homo sapiens OX=9606 GN=CCAR1 PE=1 SV=2 9.79 2714.3 - 1.19E+07 - - - -1.3996 - 1.632 0.062 - 177.1 2 2 0 -0.0013 9 0 0 0 4.39E+08 9.66E+07 - - - 0.7811 0.9989 221125_WJC_METTL3_EV_vs_WT_F02.12946.12946.2 0.00729 12-Aug R.FNDILGR.H "sp|P68400|CSK21_HUMAN,sp|Q8NEV1|CSK23_HUMAN,tr|A0A2R8YFU2|A0A2R8YFU2_HUMAN,tr|A0A2R8YD58|A0A2R8YD58_HUMAN,tr|A0A2R8YF43|A0A2R8YF43_HUMAN,tr|A0A2R8Y5A0|A0A2R8Y5A0_HUMAN,tr|A0A087WY74|A0A087WY74_HUMAN,tr|A0A2R8YDP2|A0A2R8YDP2_HUMAN,tr|E7EU96|E7EU96_HUMAN" 9 833.4396 1.15 13429 12946 2 833.439379 417.7271 Casein kinase II subunit alpha OS=Homo sapiens OX=9606 GN=CSNK2A1 PE=1 SV=1 5.84 2714.4 - 2.66E+06 - - - -0.2076 - 1.586 0.239 - 233.9 1 2 0 -0.0002 7 0 0 0 1.28E+08 1.11E+08 - - - 2.2676 0.9971 221125_WJC_METTL3_EV_vs_WT_F02.12949.12949.2 0.0291 12-Jun R.YPNLQLR[166.11].E "sp|Q14671|PUM1_HUMAN,tr|Q5T1Z8|Q5T1Z8_HUMAN,tr|H0YDK8|H0YDK8_HUMAN,tr|H0YEH2|H0YEH2_HUMAN,tr|Q5T1Z4|Q5T1Z4_HUMAN,tr|E9PR38|E9PR38_HUMAN" 6 912.5057 2.06 13432 12949 2 912.505818 457.2601 Pumilio homolog 1 OS=Homo sapiens OX=9606 GN=PUM1 PE=1 SV=3 8.75 2714.6 - 1.28E+06 - - - 0.1611 - 1.247 0.241 - 149.5 1 2 0 0.0001 7 0 0 0 8.37E+07 4.07E+07 - - - 1.5204 0.9995 221125_WJC_METTL3_EV_vs_WT_F02.12955.12955.2 0.00638 18-Oct R.VVEVVEETIK[136.11].G sp|Q5VV42|CDKAL_HUMAN 1 1151.6529 0.79 13436 12955 2 1151.650762 576.8337 Threonylcarbamoyladenosine tRNA methylthiotransferase OS=Homo sapiens OX=9606 GN=CDKAL1 PE=1 SV=1 4.25 2715.4 - 239703 - - - -1.8608 - 1.962 0.375 - 318 1 2 0 -0.0021 10 0 0 0 1.04E+07 1.31E+07 - - - 3.6913 0.9988 221125_WJC_METTL3_EV_vs_WT_F02.12958.12958.2 0.000797 12-Aug R.FNDILGR[166.11].H "sp|P68400|CSK21_HUMAN,sp|Q8NEV1|CSK23_HUMAN,tr|A0A2R8YFU2|A0A2R8YFU2_HUMAN,tr|A0A2R8YD58|A0A2R8YD58_HUMAN,tr|A0A2R8YF43|A0A2R8YF43_HUMAN,tr|A0A2R8Y5A0|A0A2R8Y5A0_HUMAN,tr|A0A087WY74|A0A087WY74_HUMAN,tr|A0A2R8YDP2|A0A2R8YDP2_HUMAN,tr|E7EU96|E7EU96_HUMAN" 9 843.4478 1.15 13437 12958 2 843.448419 422.7312 Casein kinase II subunit alpha OS=Homo sapiens OX=9606 GN=CSNK2A1 PE=1 SV=1 5.84 2715.7 - 4.82E+06 - - - 0.7078 - 1.732 0.216 - 227.6 1 2 0 0.0006 7 0 0 0 1.28E+08 1.11E+08 - - - 2.3766 0.9984 221125_WJC_METTL3_EV_vs_WT_F02.12964.12964.2 0.26 14-Jul R.ETLIDVAR[166.11].T sp|P40227|TCPZ_HUMAN 1 925.5108 0.34 13440 12964 2 925.510636 463.7627 T-complex protein 1 subunit zeta OS=Homo sapiens OX=9606 GN=CCT6A PE=1 SV=3 4.37 2716.4 - 7.57E+06 - - - -0.1945 - 1.64 0.196 - 202.6 1 2 0 -0.0002 8 0 0 0 4.16E+08 1.24E+09 - - - 1.9806 0.9905 221125_WJC_METTL3_EV_vs_WT_F02.12965.12965.2 0.358 14-Aug K.AVAISLPK[136.11].G "sp|P50454|SERPH_HUMAN,tr|E9PKH2|E9PKH2_HUMAN,tr|E9PPV6|E9PPV6_HUMAN,tr|E9PJH8|E9PJH8_HUMAN" 4 805.5153 1.53 13441 12965 2 805.514695 403.7649 Serpin H1 OS=Homo sapiens OX=9606 GN=SERPINH1 PE=1 SV=2 8.8 2716.5 - 2.11E+06 - - - -0.7387 - 1.258 0.132 - 234.7 1 2 0 -0.0006 8 0 0 0 3.58E+08 2.34E+08 - - - 0.708 0.999 221125_WJC_METTL3_EV_vs_WT_F02.12966.12966.2 0.00382 18-Jul R.ELAEDDSILK[136.11].- sp|P56385|ATP5I_HUMAN 1 1139.5801 2.38 13442 12966 2 1139.579378 570.7973 "ATP synthase subunit e, mitochondrial OS=Homo sapiens OX=9606 GN=ATP5ME PE=1 SV=2" 3.92 2716.5 - 9.79E+06 - - - -0.6634 - 1.503 0.303 - 175.3 1 2 0 -0.0008 10 0 0 0 7.63E+08 3.20E+08 - - - 2.4161 0.9999 221125_WJC_METTL3_EV_vs_WT_F02.12970.12970.2 0.00205 18-Nov K.VLVLSQDYGK.H "sp|Q01082|SPTB2_HUMAN,tr|A0A087WUZ3|A0A087WUZ3_HUMAN,tr|F8W6C1|F8W6C1_HUMAN" 3 1120.6128 1.27 13444 12970 2 1120.613196 561.3137 "Spectrin beta chain, non-erythrocytic 1 OS=Homo sapiens OX=9606 GN=SPTBN1 PE=1 SV=2" 5.81 2717 - 681893 - - - 0.3311 - 2.153 0.476 - 451.6 1 2 0 0.0004 10 0 0 0 6.79E+07 5.36E+07 - - - 4.6972 0.9856 221125_WJC_METTL3_EV_vs_WT_F02.12971.12971.2 3.6 12-Jul R.VLQVSFK[136.11].T "sp|Q12926|ELAV2_HUMAN,sp|P26378|ELAV4_HUMAN,sp|Q14576|ELAV3_HUMAN,tr|A0A494C0F8|A0A494C0F8_HUMAN,tr|A0A494C147|A0A494C147_HUMAN,tr|A0A494C1D9|A0A494C1D9_HUMAN,tr|A0A0R4J2E6|A0A0R4J2E6_HUMAN,tr|A0A0A0MRX1|A0A0A0MRX1_HUMAN,tr|B1APY9|B1APY9_HUMAN" 9 827.4996 1.53 13445 12971 2 827.499119 414.7571 ELAV-like protein 2 OS=Homo sapiens OX=9606 GN=ELAVL2 PE=1 SV=2 8.72 2717.1 - 1.92E+06 - - - -0.6296 - 1.539 0.019 - 158.4 2 2 0 -0.0005 7 0 0 0 6.16E+07 4.02E+07 - - - 0.4128 0.9778 221125_WJC_METTL3_EV_vs_WT_F02.12972.12972.2 0.0143 14-Sep G.FGGLAAAR.G sp|Q96I24|FUBP3_HUMAN 1 761.4184 1.5 13446 12972 2 761.418385 381.7165 Far upstream element-binding protein 3 OS=Homo sapiens OX=9606 GN=FUBP3 PE=1 SV=2 9.75 2717.2 - 417751 - - - -0.0499 - 1.963 0.303 - 226.5 1 1 0 0 8 0 0 0 1.18E+07 7.87E+06 - - - 3.3131 0.9998 221125_WJC_METTL3_EV_vs_WT_F02.12974.12974.2 0.000555 18-Oct R.ELAEDDSILK.- sp|P56385|ATP5I_HUMAN 1 1131.5659 2.11 13447 12974 2 1131.565952 566.7902 "ATP synthase subunit e, mitochondrial OS=Homo sapiens OX=9606 GN=ATP5ME PE=1 SV=2" 3.92 2717.4 - 2.26E+07 - - - 0.0159 - 2.041 0.465 - 385.3 1 2 0 0 10 0 0 0 6.68E+08 3.17E+08 - - - 4.4669 0.9968 221125_WJC_METTL3_EV_vs_WT_F02.12978.12978.2 0.758 12-Jul K.QLIELTR[166.11].T "sp|O75330|HMMR_HUMAN,tr|E5RIH2|E5RIH2_HUMAN,tr|E5RI30|E5RI30_HUMAN" 3 881.521 0.43 13449 12978 2 881.520818 441.7678 Hyaluronan mediated motility receptor OS=Homo sapiens OX=9606 GN=HMMR PE=1 SV=2 6 2717.8 - 531243 - - - -0.1917 - 1.448 0.164 - 175.8 1 2 0 -0.0002 7 0 0 0 5.64E+06 1.32E+07 - - - 1.4252 0.9447 221125_WJC_METTL3_EV_vs_WT_F02.12980.12980.2 1.3 14-Jun K.QALIPIAK.K "sp|Q8IWC1|MA7D3_HUMAN,tr|A0A0A0MRP0|A0A0A0MRP0_HUMAN" 2 852.5433 0.88 13450 12980 2 852.54283 427.2789 MAP7 domain-containing protein 3 OS=Homo sapiens OX=9606 GN=MAP7D3 PE=1 SV=2 8.75 2718.1 - 2.60E+06 - - - -0.5384 - 1.11 0.022 - 73 1 2 0 -0.0005 8 0 0 0 7.29E+07 8.30E+07 - - - -0.4819 0.9919 221125_WJC_METTL3_EV_vs_WT_F02.12981.12981.2 0.216 12-Aug R.VLQVSFK.T "sp|Q12926|ELAV2_HUMAN,sp|P26378|ELAV4_HUMAN,sp|Q14576|ELAV3_HUMAN,tr|A0A494C0F8|A0A494C0F8_HUMAN,tr|A0A494C147|A0A494C147_HUMAN,tr|A0A494C1D9|A0A494C1D9_HUMAN,tr|A0A0R4J2E6|A0A0R4J2E6_HUMAN,tr|A0A0A0MRX1|A0A0A0MRX1_HUMAN,tr|B1APY9|B1APY9_HUMAN" 9 819.4854 1.53 13451 12981 2 819.484297 410.75 ELAV-like protein 2 OS=Homo sapiens OX=9606 GN=ELAVL2 PE=1 SV=2 8.72 2718.1 - 2.16E+06 - - - -1.3948 - 1.488 0.098 - 244.9 1 2 0 -0.0011 7 0 0 0 6.17E+07 4.03E+07 - - - 1.0238 0.9982 221125_WJC_METTL3_EV_vs_WT_F02.12982.12982.2 0.306 16-Jun K.EVMFPPGTR.G "sp|Q96DH6|MSI2H_HUMAN,tr|B4DHE8|B4DHE8_HUMAN,tr|A0A6Q8PGD8|A0A6Q8PGD8_HUMAN,tr|A0A6Q8PF05|A0A6Q8PF05_HUMAN,tr|B4DM51|B4DM51_HUMAN" 5 1032.5063 1.99 13452 12982 2 1032.505916 517.2604 RNA-binding protein Musashi homolog 2 OS=Homo sapiens OX=9606 GN=MSI2 PE=1 SV=1 6.1 2718.3 - 928210 - - - -0.3245 - 1.517 0.22 - 86.6 1 2 0 -0.0003 9 0 0 0 2.50E+07 1.26E+07 - - - 1.8715 0.9938 221125_WJC_METTL3_EV_vs_WT_F02.12983.12983.2 0.0261 18-Oct K.MLEENTNILK[136.11].F "sp|Q9NYL9|TMOD3_HUMAN,tr|H0YKU1|H0YKU1_HUMAN,tr|H0YNJ8|H0YNJ8_HUMAN" 3 1211.6311 1.55 13453 12983 2 1211.628149 606.8228 Tropomodulin-3 OS=Homo sapiens OX=9606 GN=TMOD3 PE=1 SV=1 4.53 2718.4 - 591856 - - - -2.4554 - 1.794 0.148 - 250.9 1 2 0 -0.003 10 0 0 0 1.67E+07 1.07E+07 - - - 1.7646 0.9997 221125_WJC_METTL3_EV_vs_WT_F02.12989.12989.2 0.0024 16-Sep K.LNVITVGPR.G sp|P04040|CATA_HUMAN 1 967.5815 6.45 13457 12989 2 967.581145 484.798 Catalase OS=Homo sapiens OX=9606 GN=CAT PE=1 SV=3 9.75 2719.1 - 1.94E+06 - - - -0.3307 - 1.933 0.379 - 307.9 1 2 0 -0.0003 9 0 0 0 8.94E+07 1.39E+07 - - - 3.7469 0.9199 221125_WJC_METTL3_EV_vs_WT_F02.12993.12993.2 0.0957 18-Jun F.PAVFGDFLGR.E sp|Q14315|FLNC_HUMAN 1 1077.5607 1.01 13459 12993 2 1077.560005 539.7876 Filamin-C OS=Homo sapiens OX=9606 GN=FLNC PE=1 SV=3 6.27 2719.6 - 3.01E+07 - - - -0.6728 - 1.454 0.274 - 168.6 1 1 0 -0.0007 10 0 0 0 2.04E+09 2.02E+09 - - - 2.1094 0.9997 221125_WJC_METTL3_EV_vs_WT_F02.12994.12994.2 0.000707 22-Nov K.LLNDEDPVVVTK.A "sp|P14923|PLAK_HUMAN,tr|C9JKY1|C9JKY1_HUMAN,tr|C9JK18|C9JK18_HUMAN,tr|C9JTX4|C9JTX4_HUMAN,tr|C9J826|C9J826_HUMAN" 5 1340.7187 44.88 13460 12994 2 1340.717789 671.3666 Junction plakoglobin OS=Homo sapiens OX=9606 GN=JUP PE=1 SV=3 4.03 2719.7 - 4.03E+06 - - - -0.7145 - 1.88 0.431 - 250.1 1 2 0 -0.001 12 0 0 0 5.30E+08 1.18E+07 - - - 3.885 0.9999 221125_WJC_METTL3_EV_vs_WT_F02.12995.12995.2 0.000453 20-Nov R.LSGLADQMVAR[166.11].G sp|O95400|CD2B2_HUMAN 1 1169.6102 0.8 13461 12995 2 1169.610064 585.8124 CD2 antigen cytoplasmic tail-binding protein 2 OS=Homo sapiens OX=9606 GN=CD2BP2 PE=1 SV=1 5.84 2719.8 - 991432 - - - -0.1274 - 2.565 0.44 - 394.4 1 2 0 -0.0001 11 0 0 0 1.78E+07 2.23E+07 - - - 4.839 0.9992 221125_WJC_METTL3_EV_vs_WT_F02.12996.12996.2 0.00572 20-Oct R.VGAPLVC[160.03]C[160.03]EIK[136.11].L "sp|O95573|ACSL3_HUMAN,tr|A0A7P0TB52|A0A7P0TB52_HUMAN,tr|A0A7P0TA76|A0A7P0TA76_HUMAN,tr|A0A7P0T8L6|A0A7P0T8L6_HUMAN" 4 1252.6399 1.14 13462 12996 2 1252.638649 627.3272 Fatty acid CoA ligase Acsl3 OS=Homo sapiens OX=9606 GN=ACSL3 PE=1 SV=3 5.96 2719.9 - 525162 - - - -1.0107 - 1.796 0.283 - 276 1 2 0 -0.0013 11 0 0 0 1.67E+07 1.46E+07 - - - 2.7149 0.8175 221125_WJC_METTL3_EV_vs_WT_F02.12997.12997.2 3.95 12-Jun K.GVTLGFR[166.11].Y "sp|P32969|RL9_HUMAN,tr|D6RAN4|D6RAN4_HUMAN,tr|H0Y9V9|H0Y9V9_HUMAN,tr|A0A2R8Y5Y7|A0A2R8Y5Y7_HUMAN" 4 758.4314 0.001 13463 12997 2 758.428389 380.223 60S ribosomal protein L9 OS=Homo sapiens OX=9606 GN=RPL9 PE=1 SV=1 9.75 2720.1 - 358214 - - - -4.0281 - 1.226 0.099 - 155.4 6 2 0 -0.0031 7 0 0 0 0.00E+00 8.76E+07 - - - 0.0693 0.9994 221125_WJC_METTL3_EV_vs_WT_F02.13000.13000.2 0.197 16-Sep R.NVIEAVYSR.L "sp|O75688|PPM1B_HUMAN,tr|B8ZZF0|B8ZZF0_HUMAN,tr|A0A3B3IS24|A0A3B3IS24_HUMAN,tr|C9JIR6|C9JIR6_HUMAN" 4 1049.5506 3.09 13464 13000 2 1049.550184 525.7826 Protein phosphatase 1B OS=Homo sapiens OX=9606 GN=PPM1B PE=1 SV=1 6 2720.5 - 3.31E+06 - - - -0.3573 - 1.648 0.31 - 302.9 1 2 0 -0.0004 9 0 0 0 6.14E+09 1.98E+09 - - - 2.7758 0.9611 221125_WJC_METTL3_EV_vs_WT_F02.13001.13001.2 1.03 14-Jun K.NSVNMDLD.- "sp|Q92598|HS105_HUMAN,tr|A0A0A0MSM0|A0A0A0MSM0_HUMAN" 2 906.3753 - 13465 13001 2 906.374198 454.1949 Heat shock protein 105 kDa OS=Homo sapiens OX=9606 GN=HSPH1 PE=1 SV=1 3.89 2720.5 - 2.12E+06 - - - -1.2125 - 0.821 0.197 - 79.3 1 2 0 -0.0011 8 0 0 0 - - - - - -0.0991 1 221125_WJC_METTL3_EV_vs_WT_F02.13002.13002.2 1.77E-05 14/24 R.FSGSGSGTDFTLK.L "sp|A2NJV5|KV229_HUMAN,sp|A0A087WW87|KV240_HUMAN,sp|P06310|KV230_HUMAN,sp|A0A075B6S2|KVD29_HUMAN,sp|P01614|KVD40_HUMAN,sp|P01615|KVD28_HUMAN,sp|A0A075B6S6|KVD30_HUMAN,sp|A0A075B6P5|KV228_HUMAN,sp|A0A0A0MRZ7|KVD26_HUMAN" 9 1302.6092 999 13466 13002 2 1302.609371 652.3119 Immunoglobulin kappa variable 2-29 OS=Homo sapiens OX=9606 GN=IGKV2-29 PE=3 SV=2 5.84 2720.7 - 1.10E+06 - - - 0.1343 - 2.655 0.63 - 406.1 1 2 0 0.0002 13 0 0 0 1.80E+09 0.00E+00 - - - 6.2002 0.9996 221125_WJC_METTL3_EV_vs_WT_F02.13003.13003.2 0.000446 16-Sep K.VFLMSESEK.R sp|Q9BUQ8|DDX23_HUMAN 1 1068.5161 3.23 13467 13003 2 1068.51603 535.2653 Probable ATP-dependent RNA helicase DDX23 OS=Homo sapiens OX=9606 GN=DDX23 PE=1 SV=3 4.53 2720.8 - 843675 - - - -0.1095 - 1.566 0.402 - 267.4 1 2 0 -0.0001 9 0 0 0 1.71E+07 5.31E+06 - - - 3.3077 0.9998 221125_WJC_METTL3_EV_vs_WT_F02.13007.13007.2 0.00297 20-Nov K.LSAMMGAVAEK[136.11].K "sp|Q86U44|MTA70_HUMAN,tr|F5H6D8|F5H6D8_HUMAN,tr|H0YFV6|H0YFV6_HUMAN,tr|B4DTN4|B4DTN4_HUMAN" 4 1114.5606 0.02 13470 13007 2 1114.56076 558.2876 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 6 2721.2 - 6.13E+06 - - - 0.1418 - 2.221 0.435 - 375.1 1 2 0 0.0002 11 0 0 0 5.71E+06 2.52E+08 - - - 4.4125 0.9995 221125_WJC_METTL3_EV_vs_WT_F02.13008.13008.2 0.00618 16-Sep R.NVIEAVYSR[166.11].L "sp|O75688|PPM1B_HUMAN,tr|B8ZZF0|B8ZZF0_HUMAN,tr|A0A3B3IS24|A0A3B3IS24_HUMAN,tr|C9JIR6|C9JIR6_HUMAN" 4 1059.5588 3.07 13471 13008 2 1059.560154 530.7867 Protein phosphatase 1B OS=Homo sapiens OX=9606 GN=PPM1B PE=1 SV=1 6 2721.2 - 2.93E+06 - - - 1.2505 - 1.596 0.402 - 305.5 1 2 0 0.0013 9 0 0 0 6.15E+09 2.01E+09 - - - 3.3623 0.997 221125_WJC_METTL3_EV_vs_WT_F02.13009.13009.2 0.15 16-May R.EGLGLDVER.V sp|O15226|NKRF_HUMAN 1 986.5033 1.02 13472 13009 2 986.50387 494.2589 NF-kappa-B-repressing factor OS=Homo sapiens OX=9606 GN=NKRF PE=1 SV=2 4.14 2721.3 - 1.73E+06 - - - 0.6031 - 1.227 0.261 - 63.2 1 2 0 0.0006 9 0 0 0 1.02E+08 9.99E+07 - - - 1.5604 0.9997 221125_WJC_METTL3_EV_vs_WT_F02.13014.13014.2 0.119 20-Dec R.LSGLADQMVAR.G sp|O95400|CD2B2_HUMAN 1 1159.6019 0.8 13475 13014 2 1159.600274 580.8082 CD2 antigen cytoplasmic tail-binding protein 2 OS=Homo sapiens OX=9606 GN=CD2BP2 PE=1 SV=1 5.84 2721.9 - 1.13E+06 - - - -1.4393 - 2.417 0.346 - 492.9 1 2 0 -0.0017 11 0 0 0 1.78E+07 2.23E+07 - - - 3.9835 0.9999 221125_WJC_METTL3_EV_vs_WT_F02.13015.13015.2 0.000177 16-Nov R.IMLQNLQER[166.11].L "sp|Q8IWC1|MA7D3_HUMAN,tr|A0A0A0MRP0|A0A0A0MRP0_HUMAN" 2 1153.6153 1.02 13476 13015 2 1153.614701 577.8149 MAP7 domain-containing protein 3 OS=Homo sapiens OX=9606 GN=MAP7D3 PE=1 SV=2 6 2722 - 880418 - - - -0.5175 - 2.298 0.463 - 449.1 1 2 0 -0.0006 9 0 0 0 3.54E+07 3.48E+07 - - - 4.8677 0.9994 221125_WJC_METTL3_EV_vs_WT_F02.13016.13016.2 0.000149 20-Aug R.VGAPLVC[160.03]C[160.03]EIK.L "sp|O95573|ACSL3_HUMAN,tr|A0A7P0TB52|A0A7P0TB52_HUMAN,tr|A0A7P0TA76|A0A7P0TA76_HUMAN,tr|A0A7P0T8L6|A0A7P0T8L6_HUMAN" 4 1244.6257 1.14 13477 13016 2 1244.623157 623.3201 Fatty acid CoA ligase Acsl3 OS=Homo sapiens OX=9606 GN=ACSL3 PE=1 SV=3 5.96 2722.1 - 671495 - - - -2.0552 - 1.734 0.441 - 143.6 1 2 0 -0.0026 11 0 0 0 1.67E+07 1.46E+07 - - - 3.7865 0.9995 221125_WJC_METTL3_EV_vs_WT_F02.13018.13018.2 0.015 24-Sep R.MLAAQGVDPGLAR.A "sp|P19971|TYPH_HUMAN,tr|A0A494C0L6|A0A494C0L6_HUMAN,tr|C9JGI3|C9JGI3_HUMAN" 3 1297.6813 999 13479 13018 2 1297.683208 649.8479 Thymidine phosphorylase OS=Homo sapiens OX=9606 GN=TYMP PE=1 SV=2 5.59 2722.4 - 411331 - - - 1.5042 - 2.044 0.364 - 200.3 1 2 0 0.002 13 0 0 0 5.36E+06 0.00E+00 - - - 3.5637 0.991 221125_WJC_METTL3_EV_vs_WT_F02.13021.13021.2 0.738 14-Jul R.GLDLLTSR[166.11].S tr|H7BZF5|H7BZF5_HUMAN 1 883.5003 2.12 13480 13021 2 883.499791 442.7574 Uncharacterized protein C2orf80 (Fragment) OS=Homo sapiens OX=9606 GN=C2orf80 PE=4 SV=1 5.84 2722.7 - 2.51E+06 - - - -0.5218 - 1.628 0.045 - 165.4 2 2 0 -0.0005 8 0 0 0 1.59E+09 7.50E+08 - - - 0.7086 0.9997 221125_WJC_METTL3_EV_vs_WT_F02.13028.13028.2 9.18E-06 16-Oct K.SGVGNVFIK.N "sp|Q13310|PABP4_HUMAN,sp|Q5JQF8|PAP1M_HUMAN,tr|A0A7I2V5W9|A0A7I2V5W9_HUMAN,tr|B1ANR0|B1ANR0_HUMAN,tr|A0A7I2V4L7|A0A7I2V4L7_HUMAN,tr|B1ANR1|B1ANR1_HUMAN,tr|A0A7I2V598|A0A7I2V598_HUMAN,tr|H0YEQ8|H0YEQ8_HUMAN" 8 919.5127 1.39 13485 13028 2 919.513588 460.7636 Polyadenylate-binding protein 4 OS=Homo sapiens OX=9606 GN=PABPC4 PE=1 SV=1 8.47 2723.6 - 1.58E+07 - - - 0.9472 - 2.148 0.357 - 270 1 2 0 0.0009 9 0 0 0 6.02E+08 4.33E+08 - - - 3.8894 0.9988 221125_WJC_METTL3_EV_vs_WT_F02.13029.13029.2 0.0312 14-Aug R.DVAILQER[166.11].A "sp|Q12816|TROP_HUMAN,sp|Q9Y5V3|MAGD1_HUMAN,tr|B1AKE8|B1AKE8_HUMAN,tr|A0A087X070|A0A087X070_HUMAN,tr|G5E9N2|G5E9N2_HUMAN" 5 952.5217 1.62 13486 13029 2 952.52032 477.2681 Trophinin OS=Homo sapiens OX=9606 GN=TRO PE=1 SV=3 4.37 2723.6 - 2.19E+06 - - - -1.4645 - 1.548 0.3 - 292.2 1 2 0 -0.0014 8 0 0 0 1.14E+08 7.00E+07 - - - 2.5742 0.999 221125_WJC_METTL3_EV_vs_WT_F02.13032.13032.2 0.0363 16-Sep R.IMLQNLQER.L "sp|Q8IWC1|MA7D3_HUMAN,tr|A0A0A0MRP0|A0A0A0MRP0_HUMAN" 2 1143.607 1.02 13489 13032 2 1143.606265 572.8108 MAP7 domain-containing protein 3 OS=Homo sapiens OX=9606 GN=MAP7D3 PE=1 SV=2 6 2723.8 - 1.62E+06 - - - -0.6672 - 1.634 0.269 - 334.6 1 2 0 -0.0008 9 0 0 0 3.54E+07 3.48E+07 - - - 2.4482 0.9992 221125_WJC_METTL3_EV_vs_WT_F02.13033.13033.2 0.000158 22-Nov R.AVLLNEGGLSAK.G "sp|O75342|LX12B_HUMAN,tr|A0A3B3IRK2|A0A3B3IRK2_HUMAN" 2 1170.6608 298.36 13490 13033 2 1170.662836 586.3377 "Arachidonate 12-lipoxygenase, 12R-type OS=Homo sapiens OX=9606 GN=ALOX12B PE=1 SV=1" 6.05 2723.9 - 1.29E+06 - - - 1.7067 - 2.275 0.27 - 309.2 1 2 0 0.002 12 0 0 0 4.40E+07 1.47E+05 - - - 3.1974 0.9993 221125_WJC_METTL3_EV_vs_WT_F02.13034.13034.2 0.00632 14-Oct K.TPVIVTLK[136.11].E "sp|Q9Y4L1|HYOU1_HUMAN,tr|A0A087WWI4|A0A087WWI4_HUMAN,tr|K7EQK2|K7EQK2_HUMAN,tr|A0A087WW13|A0A087WW13_HUMAN,tr|Q9BST8|Q9BST8_HUMAN,tr|J3KTF1|J3KTF1_HUMAN,tr|A0A494C039|A0A494C039_HUMAN,tr|J3QL06|J3QL06_HUMAN,tr|A0A087X214|A0A087X214_HUMAN,tr|A0A087X054|A0A087X054_HUMAN,tr|E9PJ21|E9PJ21_HUMAN,tr|J3QLE9|J3QLE9_HUMAN,tr|J3QQH7|J3QQH7_HUMAN" 13 877.5728 0.83 13491 13034 2 877.571635 439.7937 Hypoxia up-regulated protein 1 OS=Homo sapiens OX=9606 GN=HYOU1 PE=1 SV=1 8.41 2724 - 688563 - - - -1.3332 - 1.567 0.349 - 192.8 1 2 0 -0.0012 8 0 0 0 1.68E+07 2.02E+07 - - - 2.973 0.9997 221125_WJC_METTL3_EV_vs_WT_F02.13035.13035.3 0.00208 Sep-32 R.VVHIMDFQR.G "sp|P43243|MATR3_HUMAN,tr|D6RE02|D6RE02_HUMAN,tr|B3KM87|B3KM87_HUMAN,tr|A8MXP9|A8MXP9_HUMAN,tr|D6RAY2|D6RAY2_HUMAN,tr|D6R991|D6R991_HUMAN,tr|A0A0R4J2E8|A0A0R4J2E8_HUMAN,tr|D6RAM9|D6RAM9_HUMAN,tr|D6RIA2|D6RIA2_HUMAN,tr|H0Y8T4|H0Y8T4_HUMAN,tr|D6REM6|D6REM6_HUMAN,tr|D6RBI2|D6RBI2_HUMAN" 12 1143.5859 0.91 13492 13035 3 1143.587781 382.2026 Matrin-3 OS=Homo sapiens OX=9606 GN=MATR3 PE=1 SV=2 6.71 2724.1 - 330618 - - - 1.6457 - 1.786 0.391 - 84.1 1 2 0 0.0019 9 0 0 0 3.84E+06 4.23E+06 - - - 4.6467 0.9987 221125_WJC_METTL3_EV_vs_WT_F02.13038.13038.2 0.0173 16-Jul K.DVFISAAER.D sp|P20618|PSB1_HUMAN 1 1006.5084 0.71 13493 13038 2 1006.50792 504.2615 Proteasome subunit beta type-1 OS=Homo sapiens OX=9606 GN=PSMB1 PE=1 SV=2 4.37 2724.5 - 6.01E+06 - - - -0.4372 - 1.32 0.317 - 154.3 1 2 0 -0.0004 9 0 0 0 1.72E+08 2.41E+08 - - - 2.1854 0.9979 221125_WJC_METTL3_EV_vs_WT_F02.13039.13039.2 0.12 14-Jun R.DVAILQER.A "sp|Q12816|TROP_HUMAN,sp|Q9Y5V3|MAGD1_HUMAN,tr|B1AKE8|B1AKE8_HUMAN,tr|A0A087X070|A0A087X070_HUMAN,tr|G5E9N2|G5E9N2_HUMAN" 5 942.5134 1.6 13494 13039 2 942.514539 472.264 Trophinin OS=Homo sapiens OX=9606 GN=TRO PE=1 SV=3 4.37 2724.6 - 3.40E+06 - - - 1.1607 - 1.344 0.286 - 153.2 1 2 0 0.0011 8 0 0 0 1.12E+08 7.00E+07 - - - 2.0447 0.9996 221125_WJC_METTL3_EV_vs_WT_F02.13040.13040.2 0.000278 16-Nov K.MAQALEELR[166.11].S sp|Q03252|LMNB2_HUMAN 1 1069.5466 0 13495 13040 2 1069.548573 535.7806 Lamin-B2 OS=Homo sapiens OX=9606 GN=LMNB2 PE=1 SV=4 4.53 2724.6 - 1.88E+06 - - - 1.8915 - 2.242 0.402 - 745.5 1 2 0 0.002 9 0 0 0 1.06E+05 8.51E+07 - - - 4.3453 0.9973 221125_WJC_METTL3_EV_vs_WT_F02.13041.13041.2 0.0688 12-Jun K.ANFMAIR[166.11].E "sp|O95249|GOSR1_HUMAN,tr|B4DQA8|B4DQA8_HUMAN,tr|E9PCW1|E9PCW1_HUMAN,tr|K7EJC8|K7EJC8_HUMAN,tr|G5E9T8|G5E9T8_HUMAN" 5 831.4301 0.4 13496 13041 2 831.429686 416.7223 Golgi SNAP receptor complex member 1 OS=Homo sapiens OX=9606 GN=GOSR1 PE=1 SV=1 9.79 2724.7 - 1.39E+06 - - - -0.4534 - 1.342 0.217 - 155.1 1 2 0 -0.0004 7 0 0 0 5.99E+07 1.48E+08 - - - 1.5757 0.9674 221125_WJC_METTL3_EV_vs_WT_F02.13045.13045.2 0.000719 16-Sep R.TYSLGSALR.P "sp|P08670|VIME_HUMAN,tr|B0YJC4|B0YJC4_HUMAN,tr|A0A1B0GVG8|A0A1B0GVG8_HUMAN,tr|A0A1B0GTT5|A0A1B0GTT5_HUMAN" 4 966.5134 0.22 13498 13045 2 966.512708 484.264 Vimentin OS=Homo sapiens OX=9606 GN=VIM PE=1 SV=4 8.41 2725.2 - 2.67E+06 - - - -0.7625 - 1.501 0.377 - 251.4 1 1 0 -0.0007 9 0 0 0 5.65E+07 2.60E+08 - - - 3.0003 0.9996 221125_WJC_METTL3_EV_vs_WT_F02.13046.13046.2 0.00599 20-Nov R.VVAEYLNGAVR.E "sp|Q8N983|RM43_HUMAN,tr|B1AL05|B1AL05_HUMAN,tr|H0YBU8|H0YBU8_HUMAN,tr|H0Y6Y8|H0Y6Y8_HUMAN" 4 1189.6455 0.9 13499 13046 2 1189.64605 595.83 "39S ribosomal protein L43, mitochondrial OS=Homo sapiens OX=9606 GN=MRPL43 PE=1 SV=1" 5.97 2725.3 - 1.44E+06 - - - 0.4438 - 1.69 0.407 - 146.1 1 2 0 0.0005 11 0 0 0 1.27E+08 1.40E+08 - - - 3.4665 0.958 221125_WJC_METTL3_EV_vs_WT_F02.13047.13047.2 1.64 12-Jun R.FTVAELK.Q "sp|Q13435|SF3B2_HUMAN,tr|E9PPJ0|E9PPJ0_HUMAN" 2 806.4538 1.02 13500 13047 2 806.454148 404.2342 Splicing factor 3B subunit 2 OS=Homo sapiens OX=9606 GN=SF3B2 PE=1 SV=2 6 2725.3 - 4.67E+06 - - - 0.4253 - 1.128 0.04 - 115.2 1 2 0 0.0003 7 0 0 0 3.69E+08 3.61E+08 - - - -0.282 0.9985 221125_WJC_METTL3_EV_vs_WT_F02.13050.13050.2 0.0162 16-Aug M.PLPVALQTR.L "sp|O60828|PQBP1_HUMAN,tr|A0A5H1ZRR1|A0A5H1ZRR1_HUMAN" 2 993.5971 0.76 13501 13050 2 993.595866 497.8058 Polyglutamine-binding protein 1 OS=Homo sapiens OX=9606 GN=PQBP1 PE=1 SV=1 10.18 2725.7 - 2.13E+06 - - - -1.257 - 1.424 0.297 - 155.7 1 2 0 -0.0013 9 0 0 0 9.68E+07 1.27E+08 - - - 2.2569 0.9998 221125_WJC_METTL3_EV_vs_WT_F02.13052.13052.2 0.00973 16-Aug R.ILSAEFDPK[136.11].V sp|Q14774|HLX_HUMAN 1 1026.5477 1.4 13502 13052 2 1026.547589 514.2811 H2.0-like homeobox protein OS=Homo sapiens OX=9606 GN=HLX PE=1 SV=3 4.37 2725.9 - 2.05E+06 - - - -0.1198 - 1.782 0.42 - 163.3 1 2 0 -0.0001 9 0 0 0 2.52E+08 1.80E+08 - - - 3.8145 0.9998 221125_WJC_METTL3_EV_vs_WT_F02.13053.13053.2 0.000255 14-Sep R.MVDFAGVK.D "sp|P21964|COMT_HUMAN,tr|E7EUU8|E7EUU8_HUMAN,tr|E7EMS6|E7EMS6_HUMAN,tr|F8WBW9|F8WBW9_HUMAN,tr|H7BZ45|H7BZ45_HUMAN,tr|A0A7I2V3G7|A0A7I2V3G7_HUMAN,tr|A0A7I2V370|A0A7I2V370_HUMAN" 7 865.4368 0.27 13503 13053 2 865.43669 433.7257 Catechol O-methyltransferase OS=Homo sapiens OX=9606 GN=COMT PE=1 SV=2 5.59 2726 - 1.45E+06 - - - -0.0982 - 1.832 0.401 - 324.8 1 2 0 -0.0001 8 0 0 0 6.22E+07 2.34E+08 - - - 3.8286 0.9995 221125_WJC_METTL3_EV_vs_WT_F02.13054.13054.2 0.00495 14-Aug R.LLHIEELR[166.11].E sp|Q9Y224|RTRAF_HUMAN 1 1031.6003 0.67 13504 13054 2 1031.599443 516.8074 "RNA transcription, translation and transport factor protein OS=Homo sapiens OX=9606 GN=RTRAF PE=1 SV=1" 5.4 2726.1 - 874568 - - - -0.8307 - 1.6 0.375 - 253 1 2 0 -0.0009 8 0 0 0 4.11E+07 6.12E+07 - - - 3.228 0.9986 221125_WJC_METTL3_EV_vs_WT_F02.13058.13058.2 0.0264 24-Nov K.LATVVGENGSVLR.R "sp|Q9NQS7|INCE_HUMAN,tr|E9PM67|E9PM67_HUMAN" 2 1313.7303 1.59 13506 13058 2 1313.726681 657.8724 Inner centromere protein OS=Homo sapiens OX=9606 GN=INCENP PE=1 SV=3 6 2726.6 - 475335 - - - -2.7654 - 2.342 0.282 - 316.1 1 2 0 -0.0036 13 0 0 0 5.36E+07 3.37E+07 - - - 3.3068 0.9972 221125_WJC_METTL3_EV_vs_WT_F02.13061.13061.2 0.644 24-Dec K.LATVVGENGSVLR[166.11].R "sp|Q9NQS7|INCE_HUMAN,tr|E9PM67|E9PM67_HUMAN" 2 1323.7386 1.58 13509 13061 2 1323.735745 662.8766 Inner centromere protein OS=Homo sapiens OX=9606 GN=INCENP PE=1 SV=3 6 2727 - 316904 - - - -2.1447 - 2.015 0.188 - 378.8 1 2 0 -0.0028 13 0 0 0 5.35E+07 3.37E+07 - - - 2.2268 0.9364 221125_WJC_METTL3_EV_vs_WT_F02.13063.13063.2 0.0283 18-Jul F.PAVFGDFLGR[166.11].E sp|Q14315|FLNC_HUMAN 1 1087.569 1.01 13510 13063 2 1087.567931 544.7918 Filamin-C OS=Homo sapiens OX=9606 GN=FLNC PE=1 SV=3 6.27 2727.2 - 5.14E+06 - - - -0.9829 - 1.418 0.325 - 208.2 1 1 0 -0.0011 10 0 0 0 1.97E+09 1.95E+09 - - - 2.416 0.9758 221125_WJC_METTL3_EV_vs_WT_F02.13065.13065.2 0.167 14-Aug K.DGLILTSR.G "sp|Q99497|PARK7_HUMAN,tr|K7EN27|K7EN27_HUMAN,tr|K7ELW0|K7ELW0_HUMAN" 3 873.492 2.11 13511 13065 2 873.490671 437.7533 Parkinson disease protein 7 OS=Homo sapiens OX=9606 GN=PARK7 PE=1 SV=2 5.84 2727.4 - 4.17E+07 - - - -1.5009 - 1.367 0.045 - 228.3 1 2 0 -0.0013 8 0 0 0 1.59E+09 7.52E+08 - - - 0.3158 0.9991 221125_WJC_METTL3_EV_vs_WT_F02.13066.13066.2 0.204 16-Sep M.PLPVALQTR[166.11].L "sp|O60828|PQBP1_HUMAN,tr|A0A5H1ZRR1|A0A5H1ZRR1_HUMAN" 2 1003.6054 0.76 13512 13066 2 1003.604341 502.81 Polyglutamine-binding protein 1 OS=Homo sapiens OX=9606 GN=PQBP1 PE=1 SV=1 10.18 2727.5 - 6.10E+06 - - - -1.0402 - 1.645 0.291 - 306.4 1 2 0 -0.001 9 0 0 0 9.66E+07 1.27E+08 - - - 2.63 0.9904 221125_WJC_METTL3_EV_vs_WT_F02.13067.13067.2 0.99 14-Aug R.WPVAGQIR[166.11].A sp|P78527|PRKDC_HUMAN 1 935.5217 10.73 13513 13067 2 935.521306 468.7681 DNA-dependent protein kinase catalytic subunit OS=Homo sapiens OX=9606 GN=PRKDC PE=1 SV=3 9.75 2727.5 - 1.91E+06 - - - -0.3741 - 1.246 0.128 - 237.6 1 2 0 -0.0003 8 0 0 0 8.69E+08 8.09E+07 - - - 0.6496 0.9987 221125_WJC_METTL3_EV_vs_WT_F02.13068.13068.2 0.00885 14-Sep K.LVTFENVR.M "sp|O94979|SC31A_HUMAN,tr|H7BXG7|H7BXG7_HUMAN,tr|D6RHZ5|D6RHZ5_HUMAN,tr|D6REX3|D6REX3_HUMAN,tr|H0YAB3|H0YAB3_HUMAN,tr|H0Y8V7|H0Y8V7_HUMAN" 6 976.5342 0.88 13514 13068 2 976.536239 489.2744 Protein transport protein Sec31A OS=Homo sapiens OX=9606 GN=SEC31A PE=1 SV=3 6 2727.6 - 1.83E+06 - - - 2.1075 - 1.777 0.303 - 285.4 1 2 0 0.0021 8 0 0 0 7.36E+07 8.33E+07 - - - 3.0123 0.9978 221125_WJC_METTL3_EV_vs_WT_F02.13073.13073.2 0.0216 20-Jun K.AVNSATGVPTV.- "sp|Q9H361|PABP3_HUMAN,sp|P11940|PABP1_HUMAN,tr|H0YAS6|H0YAS6_HUMAN,tr|H0YB75|H0YB75_HUMAN,tr|H0YAS7|H0YAS7_HUMAN,tr|A0A7I2YQE4|A0A7I2YQE4_HUMAN,tr|A0A7I2V649|A0A7I2V649_HUMAN,tr|H0YC10|H0YC10_HUMAN,tr|H0YAR2|H0YAR2_HUMAN,tr|E7ERJ7|E7ERJ7_HUMAN,tr|A0A7I2YQ88|A0A7I2YQ88_HUMAN,tr|A0A087WTT1|A0A087WTT1_HUMAN,tr|A0A7I2YQ90|A0A7I2YQ90_HUMAN,tr|A0A7I2V4N4|A0A7I2V4N4_HUMAN,tr|E7EQV3|E7EQV3_HUMAN" 15 1014.5346 - 13518 13073 2 1014.534352 508.2746 Polyadenylate-binding protein 3 OS=Homo sapiens OX=9606 GN=PABPC3 PE=1 SV=2 5.57 2728.2 - 5.84E+07 - - - -0.2198 - 1.276 0.274 - 129.6 1 2 0 -0.0002 11 0 0 0 - - - - - 1.724 0.9973 221125_WJC_METTL3_EV_vs_WT_F02.13075.13075.2 0.514 12-Jul K.DLILNPR.S sp|Q15393|SF3B3_HUMAN 1 839.4865 1.23 13519 13075 2 839.485073 420.7505 Splicing factor 3B subunit 3 OS=Homo sapiens OX=9606 GN=SF3B3 PE=1 SV=4 5.84 2728.5 - 4.61E+06 - - - -1.7022 - 1.508 0.225 - 240.8 1 2 0 -0.0014 7 0 0 0 2.08E+08 1.69E+08 - - - 2.004 0.9976 221125_WJC_METTL3_EV_vs_WT_F02.13079.13079.2 0.000369 18-Jul K.GPYIC[160.03]ALC[160.03]AK.E sp|P56270|MAZ_HUMAN 1 1151.5467 1.09 13521 13079 2 1151.543041 576.7806 Myc-associated zinc finger protein OS=Homo sapiens OX=9606 GN=MAZ PE=1 SV=1 8.05 2728.9 - 468691 - - - -3.2096 - 1.761 0.338 - 175.1 1 2 0 -0.0037 10 0 0 0 1.24E+07 1.13E+07 - - - 3.1159 0.9792 221125_WJC_METTL3_EV_vs_WT_F02.13084.13084.2 6.53 12-Jun K.NGFVVLK[136.11].G "sp|P63241|IF5A1_HUMAN,sp|Q9GZV4|IF5A2_HUMAN,sp|Q6IS14|IF5AL_HUMAN,tr|C9J4W5|C9J4W5_HUMAN,tr|I3L397|I3L397_HUMAN,tr|I3L504|I3L504_HUMAN,tr|C9J7B5|C9J7B5_HUMAN,tr|F8WCJ1|F8WCJ1_HUMAN" 8 783.4734 0.88 13522 13084 2 783.472851 392.744 Eukaryotic translation initiation factor 5A-1 OS=Homo sapiens OX=9606 GN=EIF5A PE=1 SV=2 8.75 2729.6 - 3.99E+06 - - - -0.7326 - 1.185 0.082 - 164.9 1 2 0 -0.0006 7 0 0 0 2.38E+08 2.69E+08 - - - 0.1843 0.9998 221125_WJC_METTL3_EV_vs_WT_F02.13086.13086.2 1.64E-05 14-Aug K.WQMNPYDR.G "sp|Q92499|DDX1_HUMAN,tr|A0A7I2V2M5|A0A7I2V2M5_HUMAN,tr|A0A7I2V430|A0A7I2V430_HUMAN,tr|A0A7I2V421|A0A7I2V421_HUMAN,tr|A0A7I2V4F0|A0A7I2V4F0_HUMAN,tr|A0A7I2V4Q0|A0A7I2V4Q0_HUMAN,tr|A0A7I2YQD0|A0A7I2YQD0_HUMAN,tr|A0A7I2V5X8|A0A7I2V5X8_HUMAN,tr|A0A7I2V4J3|A0A7I2V4J3_HUMAN,tr|A0A7I2YQ77|A0A7I2YQ77_HUMAN" 10 1108.476 1.35 13524 13086 2 1108.476537 555.2453 ATP-dependent RNA helicase DDX1 OS=Homo sapiens OX=9606 GN=DDX1 PE=1 SV=2 5.84 2729.8 - 912776 - - - 0.4718 - 1.704 0.535 - 280.9 1 2 0 0.0005 8 0 0 0 1.32E+08 9.77E+07 - - - 4.5998 0.9951 221125_WJC_METTL3_EV_vs_WT_F02.13090.13090.2 0.27 14-Jul R.MISLSYSR[166.11].L sp|O43242|PSMD3_HUMAN 1 965.488 2.26 13526 13090 2 965.486545 483.7513 26S proteasome non-ATPase regulatory subunit 3 OS=Homo sapiens OX=9606 GN=PSMD3 PE=1 SV=2 8.5 2730.2 - 1.32E+06 - - - -1.478 - 1.298 0.217 - 159.6 1 2 0 -0.0014 8 0 0 0 1.20E+08 5.33E+07 - - - 1.4299 0.9998 221125_WJC_METTL3_EV_vs_WT_F02.13091.13091.3 0.000575 Oct-40 R.NPEAALSPTFR[166.11].S "sp|Q86U44|MTA70_HUMAN,tr|B4E349|B4E349_HUMAN,tr|F5H6D8|F5H6D8_HUMAN,tr|B4DTN4|B4DTN4_HUMAN" 4 1211.6174 0.02 13527 13091 3 1211.615842 404.8797 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 6 2730.3 - 1.37E+07 - - - -1.2917 - 1.981 0.378 - 138.5 1 2 0 -0.0016 11 0 0 0 1.38E+07 6.37E+08 - - - 4.6959 0.998 221125_WJC_METTL3_EV_vs_WT_F02.13092.13092.2 0.102 20-Oct K.LTAEAIQTPLK[136.11].S sp|Q53HL2|BOREA_HUMAN 1 1191.6954 1.78 13528 13092 2 1191.694888 596.855 Borealin OS=Homo sapiens OX=9606 GN=CDCA8 PE=1 SV=2 6 2730.4 - 985198 - - - -0.4624 - 1.6 0.203 - 100.2 1 2 0 -0.0006 11 0 0 0 1.11E+08 6.25E+07 - - - 1.8117 0.9989 221125_WJC_METTL3_EV_vs_WT_F02.13094.13094.2 0.00725 12-Aug R.YPDPLIK[136.11].V "sp|P62701|RS4X_HUMAN,sp|Q8TD47|RS4Y2_HUMAN" 2 852.4837 1.16 13529 13094 2 852.482461 427.2491 "40S ribosomal protein S4, X isoform OS=Homo sapiens OX=9606 GN=RPS4X PE=1 SV=2" 5.83 2730.6 - 5.34E+06 - - - -1.4006 - 1.529 0.308 - 184.2 1 2 0 -0.0012 7 0 0 0 2.70E+08 2.32E+08 - - - 2.6609 0.9998 221125_WJC_METTL3_EV_vs_WT_F02.13096.13096.2 2.08E-05 18-Aug K.LTPSGYEWGR.Q sp|Q6P2Q9|PRP8_HUMAN 1 1164.5564 0.19 13530 13096 2 1164.557738 583.2855 Pre-mRNA-processing-splicing factor 8 OS=Homo sapiens OX=9606 GN=PRPF8 PE=1 SV=2 6 2730.9 - 1.35E+06 - - - 1.1721 - 1.91 0.491 - 266.4 1 2 0 0.0014 10 0 0 0 3.57E+07 1.86E+08 - - - 4.4734 0.9995 221125_WJC_METTL3_EV_vs_WT_F02.13105.13105.2 0.000871 18-Sep R.IVTSEEVIIR.D "sp|Q9Y639|NPTN_HUMAN,tr|H3BQ94|H3BQ94_HUMAN,tr|Q9UFM8|Q9UFM8_HUMAN" 3 1157.6656 1.06 13536 13105 2 1157.665477 579.8401 Neuroplastin OS=Homo sapiens OX=9606 GN=NPTN PE=1 SV=2 4.53 2731.9 - 802033 - - - -0.0967 - 1.867 0.314 - 207.8 1 2 0 -0.0001 10 0 0 0 4.59E+07 4.32E+07 - - - 3.1029 0.9999 221125_WJC_METTL3_EV_vs_WT_F02.13109.13109.2 1.95E-06 20-Nov R.NPEAALSPTFR.S "sp|Q86U44|MTA70_HUMAN,tr|B4E349|B4E349_HUMAN,tr|F5H6D8|F5H6D8_HUMAN,tr|B4DTN4|B4DTN4_HUMAN" 4 1201.6091 0.02 13538 13109 2 1201.607939 601.8118 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 6 2732.4 - 7.35E+06 - - - -0.997 - 2.323 0.583 - 567.8 1 2 0 -0.0012 11 0 0 0 2.43E+08 1.11E+10 - - - 5.6268 0.9993 221125_WJC_METTL3_EV_vs_WT_F02.13112.13112.2 0.00527 18-Aug R.IVTSEEVIIR[166.11].D "sp|Q9Y639|NPTN_HUMAN,tr|H3BQ94|H3BQ94_HUMAN,tr|Q9UFM8|Q9UFM8_HUMAN" 3 1167.6739 1.06 13541 13112 2 1167.677124 584.8442 Neuroplastin OS=Homo sapiens OX=9606 GN=NPTN PE=1 SV=2 4.53 2732.7 - 1.19E+06 - - - 2.7962 - 1.818 0.491 - 194.2 1 2 0 0.0033 10 0 0 0 4.59E+07 4.32E+07 - - - 4.335 0.9996 221125_WJC_METTL3_EV_vs_WT_F02.13119.13119.2 0.00384 16-Sep K.AENLGEVLR.G "sp|Q92544|TM9S4_HUMAN,tr|A0A0C4DFM1|A0A0C4DFM1_HUMAN" 2 999.5349 1.58 13546 13119 2 999.533669 500.7747 Transmembrane 9 superfamily member 4 OS=Homo sapiens OX=9606 GN=TM9SF4 PE=1 SV=2 4.53 2733.5 - 2.53E+06 - - - -1.2406 - 1.893 0.364 - 388.4 1 2 0 -0.0012 9 0 0 0 7.61E+07 4.81E+07 - - - 3.5754 0.9991 221125_WJC_METTL3_EV_vs_WT_F02.13121.13121.2 0.000183 18-Jul K.YVTDVGVLQR.H "sp|O75419|CDC45_HUMAN,tr|A0A5F9ZH29|A0A5F9ZH29_HUMAN,tr|A0A5K1VW85|A0A5K1VW85_HUMAN" 3 1148.619 0.08 13548 13121 2 1148.621444 575.3168 Cell division control protein 45 homolog OS=Homo sapiens OX=9606 GN=CDC45 PE=1 SV=1 5.84 2733.7 - 287059 - - - 2.1513 - 1.564 0.413 - 123.8 1 2 0 0.0025 10 0 0 0 9.43E+06 1.18E+08 - - - 3.339 0.9996 221125_WJC_METTL3_EV_vs_WT_F02.13124.13124.2 0.00361 18-Sep K.WLAGDVPAAR.S sp|O94906|PRP6_HUMAN 1 1054.556 1.52 13549 13124 2 1054.555211 528.2853 Pre-mRNA-processing factor 6 OS=Homo sapiens OX=9606 GN=PRPF6 PE=1 SV=1 5.84 2734.1 - 6.07E+06 - - - -0.7283 - 1.968 0.317 - 333.4 1 2 0 -0.0008 10 0 0 0 2.97E+08 1.95E+08 - - - 3.2719 0.994 221125_WJC_METTL3_EV_vs_WT_F02.13127.13127.2 0.112 14-Jun R.FTAFYASR[166.11].H "sp|Q13616|CUL1_HUMAN,tr|A0A0C4DGX4|A0A0C4DGX4_HUMAN,tr|A0A590UJ50|A0A590UJ50_HUMAN,tr|A0A590UJR3|A0A590UJR3_HUMAN,tr|A0A590UJ56|A0A590UJ56_HUMAN,tr|A0A590UJC4|A0A590UJC4_HUMAN,tr|A0A590UK34|A0A590UK34_HUMAN" 7 971.474 0.02 13552 13127 2 971.475786 486.7443 Cullin-1 OS=Homo sapiens OX=9606 GN=CUL1 PE=1 SV=2 8.75 2734.3 - 1.02E+06 - - - 1.8004 - 1.211 0.253 - 76.2 1 2 0 0.0017 8 0 0 0 8.72E+06 5.47E+08 - - - 1.4865 0.9967 221125_WJC_METTL3_EV_vs_WT_F02.13128.13128.2 0.000263 16-Oct R.YQGVNLYVK.N "sp|Q4VXU2|PAP1L_HUMAN,sp|P11940|PABP1_HUMAN,tr|A0A7I2YQE4|A0A7I2YQE4_HUMAN,tr|A0A6Q8JFT6|A0A6Q8JFT6_HUMAN,tr|H0YAR2|H0YAR2_HUMAN,tr|E7ERJ7|E7ERJ7_HUMAN,tr|A0A7I2YQ88|A0A7I2YQ88_HUMAN,tr|A0A6I8PS38|A0A6I8PS38_HUMAN,tr|A0A6I8PLA1|A0A6I8PLA1_HUMAN,tr|A0A087WTT1|A0A087WTT1_HUMAN,tr|H0YAP2|H0YAP2_HUMAN,tr|A0A7I2V4N4|A0A7I2V4N4_HUMAN,tr|E7EQV3|E7EQV3_HUMAN" 13 1082.576 1.18 13553 13128 2 1082.57155 542.2953 Polyadenylate-binding protein 1-like OS=Homo sapiens OX=9606 GN=PABPC1L PE=2 SV=1 8.5 2734.4 - 737292 - - - -4.1531 - 1.59 0.423 - 197 1 2 0 -0.0045 9 0 0 0 1.34E+09 1.14E+09 - - - 3.5055 0.9997 221125_WJC_METTL3_EV_vs_WT_F02.13132.13132.2 0.00899 16-Nov R.YQGVNLYVK[136.11].N "sp|Q4VXU2|PAP1L_HUMAN,sp|P11940|PABP1_HUMAN,tr|A0A7I2YQE4|A0A7I2YQE4_HUMAN,tr|A0A6Q8JFT6|A0A6Q8JFT6_HUMAN,tr|H0YAR2|H0YAR2_HUMAN,tr|E7ERJ7|E7ERJ7_HUMAN,tr|A0A7I2YQ88|A0A7I2YQ88_HUMAN,tr|A0A6I8PS38|A0A6I8PS38_HUMAN,tr|A0A6I8PLA1|A0A6I8PLA1_HUMAN,tr|A0A087WTT1|A0A087WTT1_HUMAN,tr|H0YAP2|H0YAP2_HUMAN,tr|A0A7I2V4N4|A0A7I2V4N4_HUMAN,tr|E7EQV3|E7EQV3_HUMAN" 13 1090.5902 1.18 13555 13132 2 1090.590201 546.3024 Polyadenylate-binding protein 1-like OS=Homo sapiens OX=9606 GN=PABPC1L PE=2 SV=1 8.5 2735 - 2.72E+06 - - - -0.0413 - 2.069 0.322 - 246.3 1 2 0 0 9 0 0 0 1.34E+09 1.14E+09 - - - 3.5227 0.9984 221125_WJC_METTL3_EV_vs_WT_F02.13133.13133.2 0.00785 20-Aug K.GLGLDESGLAK[136.11].Q sp|Q9Y265|RUVB1_HUMAN 1 1066.575 3.11 13556 13133 2 1066.576463 534.2948 RuvB-like 1 OS=Homo sapiens OX=9606 GN=RUVBL1 PE=1 SV=1 4.37 2735 - 2.26E+06 - - - 1.382 - 1.688 0.259 - 140.6 1 2 0 0.0015 11 0 0 0 4.55E+08 1.46E+08 - - - 2.3698 0.9939 221125_WJC_METTL3_EV_vs_WT_F02.13135.13135.2 0.292 12-Aug R.LSDIWAK.T "sp|Q9UBM7|DHCR7_HUMAN,tr|E9PIP9|E9PIP9_HUMAN,tr|E9PJ54|E9PJ54_HUMAN,tr|E9PRL8|E9PRL8_HUMAN,tr|E9PLZ2|E9PLZ2_HUMAN,tr|E9PM00|E9PM00_HUMAN,tr|A0A804HI25|A0A804HI25_HUMAN,tr|A0A804HJQ7|A0A804HJQ7_HUMAN,tr|A0A804HJI8|A0A804HJI8_HUMAN,tr|A0A804HL56|A0A804HL56_HUMAN,tr|E9PQ71|E9PQ71_HUMAN" 11 831.4491 1.02 13558 13135 2 831.448526 416.7318 7-dehydrocholesterol reductase OS=Homo sapiens OX=9606 GN=DHCR7 PE=1 SV=1 5.84 2735.2 - 1.34E+06 - - - -0.635 - 1.798 0.013 - 182.1 1 2 0 -0.0005 7 0 0 0 7.50E+07 7.39E+07 - - - 0.9958 0.999 221125_WJC_METTL3_EV_vs_WT_F02.13136.13136.2 0.0367 18-Aug K.VLLPEYGGTK.V "sp|P61604|CH10_HUMAN,tr|B8ZZ54|B8ZZ54_HUMAN,tr|B8ZZL8|B8ZZL8_HUMAN" 3 1075.5914 2.32 13559 13136 2 1075.592765 538.803 "10 kDa heat shock protein, mitochondrial OS=Homo sapiens OX=9606 GN=HSPE1 PE=1 SV=2" 5.97 2735.2 - 1.01E+06 - - - 1.3053 - 1.499 0.347 - 192.4 1 2 0 0.0014 10 0 0 0 2.78E+08 1.20E+08 - - - 2.7334 0.9998 221125_WJC_METTL3_EV_vs_WT_F02.13141.13141.2 2.02E-06 14-Oct K.WQMNPYDR[166.11].G "sp|Q92499|DDX1_HUMAN,tr|A0A7I2V2M5|A0A7I2V2M5_HUMAN,tr|A0A7I2V430|A0A7I2V430_HUMAN,tr|A0A7I2V421|A0A7I2V421_HUMAN,tr|A0A7I2V4F0|A0A7I2V4F0_HUMAN,tr|A0A7I2V4Q0|A0A7I2V4Q0_HUMAN,tr|A0A7I2YQD0|A0A7I2YQD0_HUMAN,tr|A0A7I2V5X8|A0A7I2V5X8_HUMAN,tr|A0A7I2V4J3|A0A7I2V4J3_HUMAN,tr|A0A7I2YQ77|A0A7I2YQ77_HUMAN" 10 1118.4843 1.34 13562 13141 2 1118.483187 560.2494 ATP-dependent RNA helicase DDX1 OS=Homo sapiens OX=9606 GN=DDX1 PE=1 SV=2 5.84 2735.8 - 3.02E+06 - - - -0.9808 - 2.029 0.468 - 449 1 2 0 -0.0011 8 0 0 0 1.31E+08 9.77E+07 - - - 4.6312 0.9992 221125_WJC_METTL3_EV_vs_WT_F02.13142.13142.2 0.047 14-Aug K.AQLLEIAK[136.11].A "sp|P18583|SON_HUMAN,tr|H7C1M2|H7C1M2_HUMAN,tr|H7C2G8|H7C2G8_HUMAN,tr|J3QSZ5|J3QSZ5_HUMAN" 4 892.5473 1.21 13563 13142 2 892.545947 447.2809 Protein SON OS=Homo sapiens OX=9606 GN=SON PE=1 SV=4 6.05 2735.9 - 1.66E+06 - - - -1.5361 - 1.77 0.301 - 248 1 2 0 -0.0014 8 0 0 0 7.78E+07 6.43E+07 - - - 2.9858 0.98 221125_WJC_METTL3_EV_vs_WT_F02.13146.13146.2 0.324 14-Aug Q.AFIEMETR.E "sp|P43243|MATR3_HUMAN,tr|B3KM87|B3KM87_HUMAN,tr|A8MXP9|A8MXP9_HUMAN,tr|A0A0R4J2E8|A0A0R4J2E8_HUMAN,tr|H0Y8T4|H0Y8T4_HUMAN,tr|D6REM6|D6REM6_HUMAN" 6 995.4746 1.3 13565 13146 2 995.474662 498.7446 Matrin-3 OS=Homo sapiens OX=9606 GN=MATR3 PE=1 SV=2 4.53 2736.4 - 1.29E+06 - - - 0.0452 - 1.672 0.385 - 293.5 1 1 0 0 8 0 0 0 5.57E+07 4.30E+07 - - - 3.4349 0.9986 221125_WJC_METTL3_EV_vs_WT_F02.13156.13156.2 0.0789 14-Jul K.AQLLEIAK.A "sp|P18583|SON_HUMAN,tr|H7C1M2|H7C1M2_HUMAN,tr|H7C2G8|H7C2G8_HUMAN,tr|J3QSZ5|J3QSZ5_HUMAN" 4 884.5331 1.21 13569 13156 2 884.533326 443.2738 Protein SON OS=Homo sapiens OX=9606 GN=SON PE=1 SV=4 6.05 2737.7 - 2.18E+06 - - - 0.2352 - 1.569 0.249 - 137 2 2 0 0.0002 8 0 0 0 7.78E+07 6.43E+07 - - - 2.1041 0.9694 221125_WJC_METTL3_EV_vs_WT_F02.13158.13158.2 0.635 14-May K.AAAISTSR[166.11].V "sp|Q9NVU7|SDA1_HUMAN,tr|E7EW05|E7EW05_HUMAN" 2 785.4271 0.04 13570 13158 2 785.428313 393.7208 Protein SDA1 homolog OS=Homo sapiens OX=9606 GN=SDAD1 PE=1 SV=3 9.79 2738 - 5.17E+06 - - - 1.5609 - 1.119 0.178 - 48.5 10 2 0 0.0012 8 0 0 0 1.08E+07 2.79E+08 - - - 0.2477 0.9988 221125_WJC_METTL3_EV_vs_WT_F02.13167.13167.2 0.00313 14-Aug K.VPDFSEYR[166.11].R "sp|P0C7P4|UCRIL_HUMAN,sp|P47985|UCRI_HUMAN" 2 1021.4744 1.12 13574 13167 2 1021.475111 511.7445 Putative cytochrome b-c1 complex subunit Rieske-like protein 1 OS=Homo sapiens OX=9606 GN=UQCRFS1P1 PE=5 SV=1 4.37 2739.1 - 2.03E+06 - - - 0.6657 - 1.355 0.32 - 211.4 1 2 0 0.0007 8 0 0 0 1.05E+08 9.35E+07 - - - 2.3206 0.9994 221125_WJC_METTL3_EV_vs_WT_F02.13173.13173.2 0.0055 16-Aug K.VLEGMEVVR[166.11].K "sp|P23284|PPIB_HUMAN,tr|A0A7P0Z497|A0A7P0Z497_HUMAN,tr|A0A7P0TB45|A0A7P0TB45_HUMAN" 3 1040.5564 0.3 13579 13173 2 1040.556799 521.2855 Peptidyl-prolyl cis-trans isomerase B OS=Homo sapiens OX=9606 GN=PPIB PE=1 SV=2 4.53 2739.8 - 3.33E+06 - - - 0.3969 - 1.628 0.332 - 252.9 1 2 0 0.0004 9 0 0 0 1.08E+08 3.57E+08 - - - 2.903 0.9193 221125_WJC_METTL3_EV_vs_WT_F02.13175.13175.2 5.56 12-Apr K.LFNIHED.- "sp|O95831|AIFM1_HUMAN,tr|A0A6Q8PHJ9|A0A6Q8PHJ9_HUMAN,tr|E9PMA0|E9PMA0_HUMAN,tr|A0A7I2PK44|A0A7I2PK44_HUMAN,tr|A0A6Q8PG15|A0A6Q8PG15_HUMAN,tr|A0A6Q8PFE1|A0A6Q8PFE1_HUMAN,tr|A0A6Q8PHJ4|A0A6Q8PHJ4_HUMAN,tr|A0A6Q8PHC0|A0A6Q8PHC0_HUMAN,tr|A0A6Q8PFM5|A0A6Q8PFM5_HUMAN" 9 886.4185 - 13580 13175 2 886.418623 444.2165 "Apoptosis-inducing factor 1, mitochondrial OS=Homo sapiens OX=9606 GN=AIFM1 PE=1 SV=1" 4.64 2740 - 3.79E+06 - - - 0.1591 - 0.876 0.086 - 34.7 1 2 0 0.0001 7 0 0 0 - - - - - -0.7433 0.9932 221125_WJC_METTL3_EV_vs_WT_F02.13182.13182.2 0.142 12-Aug R.LSDIWAK[136.11].T "sp|Q9UBM7|DHCR7_HUMAN,tr|E9PIP9|E9PIP9_HUMAN,tr|E9PJ54|E9PJ54_HUMAN,tr|E9PRL8|E9PRL8_HUMAN,tr|E9PLZ2|E9PLZ2_HUMAN,tr|E9PM00|E9PM00_HUMAN,tr|A0A804HI25|A0A804HI25_HUMAN,tr|A0A804HJQ7|A0A804HJQ7_HUMAN,tr|A0A804HJI8|A0A804HJI8_HUMAN,tr|A0A804HL56|A0A804HL56_HUMAN,tr|E9PQ71|E9PQ71_HUMAN" 11 839.4633 1.03 13584 13182 2 839.461561 420.7389 7-dehydrocholesterol reductase OS=Homo sapiens OX=9606 GN=DHCR7 PE=1 SV=1 5.84 2740.8 - 1.90E+06 - - - -2.0168 - 1.717 0.094 - 159.7 1 2 0 -0.0017 7 0 0 0 7.51E+07 7.30E+07 - - - 1.4476 0.9999 221125_WJC_METTL3_EV_vs_WT_F02.13183.13183.2 0.00056 20-Dec K.LTAEAIQTPLK.S sp|Q53HL2|BOREA_HUMAN 1 1183.6812 1.78 13585 13183 2 1183.681499 592.8479 Borealin OS=Homo sapiens OX=9606 GN=CDCA8 PE=1 SV=2 6 2740.9 - 2.43E+06 - - - 0.2197 - 2.426 0.464 - 450.6 1 2 0 0.0003 11 0 0 0 1.11E+08 6.26E+07 - - - 4.8655 0.9997 221125_WJC_METTL3_EV_vs_WT_F02.13184.13184.2 0.0112 14-Aug K.VPDFSEYR.R "sp|P0C7P4|UCRIL_HUMAN,sp|P47985|UCRI_HUMAN" 2 1011.4662 1.09 13586 13184 2 1011.466442 506.7404 Putative cytochrome b-c1 complex subunit Rieske-like protein 1 OS=Homo sapiens OX=9606 GN=UQCRFS1P1 PE=5 SV=1 4.37 2740.9 - 2.81E+06 - - - 0.2778 - 1.659 0.392 - 261.8 1 2 0 0.0003 8 0 0 0 1.05E+08 9.64E+07 - - - 3.4629 0.9994 221125_WJC_METTL3_EV_vs_WT_F02.13185.13185.2 0.00693 12-Jul K.YLTWASR.Q "sp|P01876|IGHA1_HUMAN,sp|P01877|IGHA2_HUMAN,tr|A0A286YEY1|A0A286YEY1_HUMAN,tr|A0A0G2JMB2|A0A0G2JMB2_HUMAN,tr|A0A286YEY5|A0A286YEY5_HUMAN" 5 895.4552 33.88 13587 13185 2 895.455139 448.7349 Immunoglobulin heavy constant alpha 1 OS=Homo sapiens OX=9606 GN=IGHA1 PE=1 SV=2 8.75 2741 - 1.85E+06 - - - -0.0704 - 1.412 0.357 - 189.9 1 2 0 -0.0001 7 0 0 0 1.25E+08 3.69E+06 - - - 2.771 0.996 221125_WJC_METTL3_EV_vs_WT_F02.13192.13192.2 0.0962 12-May R.YPNLQLR.E "sp|Q14671|PUM1_HUMAN,tr|Q5T1Z8|Q5T1Z8_HUMAN,tr|H0YDK8|H0YDK8_HUMAN,tr|H0YEH2|H0YEH2_HUMAN,tr|Q5T1Z4|Q5T1Z4_HUMAN,tr|E9PR38|E9PR38_HUMAN" 6 902.4974 2.51 13592 13192 2 902.496832 452.256 Pumilio homolog 1 OS=Homo sapiens OX=9606 GN=PUM1 PE=1 SV=3 8.75 2741.7 - 3.82E+06 - - - -0.6305 - 1.378 0.188 - 99.9 2 2 0 -0.0006 7 0 0 0 2.46E+08 9.81E+07 - - - 1.3109 0.9966 221125_WJC_METTL3_EV_vs_WT_F02.13193.13193.2 0.00337 16-Sep K.VLEGMEVVR.K "sp|P23284|PPIB_HUMAN,tr|A0A7P0Z497|A0A7P0Z497_HUMAN,tr|A0A7P0TB45|A0A7P0TB45_HUMAN" 3 1030.5481 0.29 13593 13193 2 1030.543365 516.2813 Peptidyl-prolyl cis-trans isomerase B OS=Homo sapiens OX=9606 GN=PPIB PE=1 SV=2 4.53 2741.8 - 3.11E+06 - - - -4.6102 - 1.835 0.416 - 291.4 1 2 0 -0.0048 9 0 0 0 1.05E+08 3.55E+08 - - - 3.8683 0.9996 221125_WJC_METTL3_EV_vs_WT_F02.13199.13199.2 0.000461 14-Jul R.LTPEDFAR.A "sp|Q9NP79|VTA1_HUMAN,tr|Q5TGM0|Q5TGM0_HUMAN,tr|A0A087WY55|A0A087WY55_HUMAN" 3 947.4712 1.49 13597 13199 2 947.471438 474.7429 Vacuolar protein sorting-associated protein VTA1 homolog OS=Homo sapiens OX=9606 GN=VTA1 PE=1 SV=1 4.37 2742.4 - 2.83E+06 - - - 0.2026 - 1.422 0.424 - 249.2 1 2 0 0.0002 8 0 0 0 8.01E+08 5.36E+08 - - - 3.2344 0.9966 221125_WJC_METTL3_EV_vs_WT_F02.13200.13200.2 0.419 16-Jun K.VLSLVDDPR.N "sp|Q9BZE1|RM37_HUMAN,tr|S4R369|S4R369_HUMAN" 2 1012.5553 0.98 13598 13200 2 1012.555722 507.2849 "39S ribosomal protein L37, mitochondrial OS=Homo sapiens OX=9606 GN=MRPL37 PE=1 SV=2" 4.21 2742.4 - 3.02E+06 - - - 0.4069 - 1.142 0.272 - 117.8 1 2 0 0.0004 9 0 0 0 9.80E+07 9.95E+07 - - - 1.434 0.9947 221125_WJC_METTL3_EV_vs_WT_F02.13201.13201.2 0.254 20-Aug R.LVVVDENDVVK.G "sp|P54619|AAKG1_HUMAN,tr|H0YIC9|H0YIC9_HUMAN,tr|H0YHF8|H0YHF8_HUMAN,tr|F8VYY9|F8VYY9_HUMAN" 4 1227.6711 0.58 13599 13201 2 1227.672689 614.8428 5'-AMP-activated protein kinase subunit gamma-1 OS=Homo sapiens OX=9606 GN=PRKAG1 PE=1 SV=1 4.03 2742.6 - 264579 - - - 1.3204 - 1.338 0.21 - 158 1 2 0 0.0016 11 0 0 0 8.08E+06 1.38E+07 - - - 1.3793 0.9829 221125_WJC_METTL3_EV_vs_WT_F02.13206.13206.2 1.45 18-Jul K.SLADGILLC[160.03]K[136.11].M "sp|Q14651|PLSI_HUMAN,tr|C9JAM8|C9JAM8_HUMAN" 2 1096.6042 6.79 13602 13206 2 1096.603774 549.3094 Plastin-1 OS=Homo sapiens OX=9606 GN=PLS1 PE=1 SV=2 5.55 2743.1 - 2.44E+06 - - - -0.3711 - 1.424 0.061 - 90 3 2 0 -0.0004 10 0 0 0 9.37E+08 1.38E+08 - - - 0.2649 0.7865 221125_WJC_METTL3_EV_vs_WT_F02.13212.13212.2 0.382 14-Jun R.VAEELFRA.Q tr|A0A494C0P5|A0A494C0P5_HUMAN 1 933.492 1.15 13606 13212 2 933.492221 467.7533 Kinesin-like protein KIF25 OS=Homo sapiens OX=9606 GN=KIF25 PE=3 SV=1 4.53 2743.8 - 1.16E+06 - - - 0.256 - 1.326 0.177 - 111.7 1 1 0 0.0002 8 0 0 0 3.22E+07 2.79E+07 - - - 1.1992 0.9979 221125_WJC_METTL3_EV_vs_WT_F02.13213.13213.2 0.0169 16-Sep K.LSPEDYTLK.V "sp|P07339|CATD_HUMAN,tr|A0A1B0GW44|A0A1B0GW44_HUMAN,tr|A0A1B0GVD5|A0A1B0GVD5_HUMAN,tr|A0A1B0GV23|A0A1B0GV23_HUMAN,tr|C9JH19|C9JH19_HUMAN,tr|H7C469|H7C469_HUMAN,tr|A0A1B0GWE8|A0A1B0GWE8_HUMAN,tr|A0A1B0GU03|A0A1B0GU03_HUMAN,tr|A0A1B0GVP3|A0A1B0GVP3_HUMAN,tr|A0A1B0GU92|A0A1B0GU92_HUMAN,tr|A0A1B0GVF1|A0A1B0GVF1_HUMAN,tr|F8W787|F8W787_HUMAN" 12 1064.539 2.89 13607 13213 2 1064.53544 533.2768 Cathepsin D OS=Homo sapiens OX=9606 GN=CTSD PE=1 SV=1 4.37 2743.8 - 2.09E+06 - - - -3.3357 - 1.719 0.369 - 284.8 1 2 0 -0.0036 9 0 0 0 1.25E+08 4.34E+07 - - - 3.3326 0.9725 221125_WJC_METTL3_EV_vs_WT_F02.13214.13214.2 0.0583 14-Sep R.PLEMIEPR[166.11].T "sp|P62249|RS16_HUMAN,tr|M0R3H0|M0R3H0_HUMAN,tr|M0R1M5|M0R1M5_HUMAN,tr|Q6IPX4|Q6IPX4_HUMAN" 4 993.5193 1.06 13608 13214 2 993.518884 497.7669 40S ribosomal protein S16 OS=Homo sapiens OX=9606 GN=RPS16 PE=1 SV=2 4.53 2743.9 - 734762 - - - -0.3905 - 1.731 0.325 - 285.8 1 1 0 -0.0004 8 0 0 0 7.17E+07 6.79E+07 - - - 3.0962 1 221125_WJC_METTL3_EV_vs_WT_F02.13223.13223.2 7.92E-08 20-Dec K.LLETEC[160.03]PQYIR.K sp|P05109|S10A8_HUMAN 1 1420.7021 999 13615 13223 2 1420.701992 711.3583 Protein S100-A8 OS=Homo sapiens OX=9606 GN=S100A8 PE=1 SV=1 4.53 2745 - 591267 - - - -0.0415 - 2.657 0.607 - 580.6 1 2 0 -0.0001 11 0 0 0 1.62E+09 0.00E+00 - - - 6.1678 0.9998 221125_WJC_METTL3_EV_vs_WT_F02.13228.13228.2 0.000818 18-Dec K.FGEVVDC[160.03]TIK[136.11].M "sp|Q99729|ROAA_HUMAN,sp|Q14103|HNRPD_HUMAN,sp|O14979|HNRDL_HUMAN,tr|H0Y8G5|H0Y8G5_HUMAN,tr|A0A087WUK2|A0A087WUK2_HUMAN,tr|D6RF44|D6RF44_HUMAN,tr|D6RD83|D6RD83_HUMAN,tr|D6R9P3|D6R9P3_HUMAN,tr|D6RBQ9|D6RBQ9_HUMAN,tr|D6RAF8|D6RAF8_HUMAN,tr|H0YA96|H0YA96_HUMAN,tr|D6RD18|D6RD18_HUMAN,tr|D6RBZ0|D6RBZ0_HUMAN" 13 1174.5784 1.2 13618 13228 2 1174.578415 588.2965 Heterogeneous nuclear ribonucleoprotein A\B OS=Homo sapiens OX=9606 GN=HNRNPAB PE=1 SV=2 4.37 2745.7 - 1.33E+06 - - - 0.046 - 2.209 0.437 - 444.3 1 2 0 0.0001 10 0 0 0 6.89E+08 5.76E+08 - - - 4.4809 0.9998 221125_WJC_METTL3_EV_vs_WT_F02.13230.13230.2 0.000207 20-Oct R.LVVVDENDVVK[136.11].G "sp|P54619|AAKG1_HUMAN,tr|H0YIC9|H0YIC9_HUMAN,tr|H0YHF8|H0YHF8_HUMAN,tr|F8VYY9|F8VYY9_HUMAN" 4 1235.6853 0.58 13620 13230 2 1235.68617 618.8499 5'-AMP-activated protein kinase subunit gamma-1 OS=Homo sapiens OX=9606 GN=PRKAG1 PE=1 SV=1 4.03 2746 - 559226 - - - 0.73 - 2.144 0.475 - 280.5 1 2 0 0.0009 11 0 0 0 8.08E+06 1.38E+07 - - - 4.6123 0.9968 221125_WJC_METTL3_EV_vs_WT_F02.13241.13241.2 0.000714 18-Sep K.FPLTTESAMK.K "sp|P62750|RL23A_HUMAN,tr|H7BY10|H7BY10_HUMAN,tr|K7ERT8|K7ERT8_HUMAN,tr|A8MUS3|A8MUS3_HUMAN,tr|K7EJV9|K7EJV9_HUMAN" 5 1123.5583 0.62 13627 13241 2 1123.562278 562.7864 60S ribosomal protein L23a OS=Homo sapiens OX=9606 GN=RPL23A PE=1 SV=1 6 2747.4 - 1.19E+06 - - - 3.4987 - 1.519 0.386 - 225.1 1 2 0 0.0039 10 0 0 0 3.71E+07 6.00E+07 - - - 3.0577 0.9726 221125_WJC_METTL3_EV_vs_WT_F02.13244.13244.2 0.0219 14-Sep R.PLEMIEPR.T "sp|P62249|RS16_HUMAN,tr|M0R3H0|M0R3H0_HUMAN,tr|M0R1M5|M0R1M5_HUMAN,tr|Q6IPX4|Q6IPX4_HUMAN" 4 983.511 1.05 13630 13244 2 983.509819 492.7628 40S ribosomal protein S16 OS=Homo sapiens OX=9606 GN=RPS16 PE=1 SV=2 4.53 2747.6 - 850642 - - - -1.2028 - 1.867 0.333 - 299.9 1 1 0 -0.0012 8 0 0 0 7.17E+07 6.82E+07 - - - 3.3831 0.9854 221125_WJC_METTL3_EV_vs_WT_F02.13245.13245.2 0.00211 20-Sep Y.MVGPIEEAVAK.A sp|P06576|ATPB_HUMAN 1 1142.6005 1.37 13631 13245 2 1142.601375 572.3075 "ATP synthase subunit beta, mitochondrial OS=Homo sapiens OX=9606 GN=ATP5F1B PE=1 SV=3" 4.53 2747.7 - 552787 - - - 0.7255 - 1.893 0.44 - 190.8 1 1 0 0.0008 11 0 0 0 1.48E+07 1.08E+07 - - - 4.017 0.9998 221125_WJC_METTL3_EV_vs_WT_F02.13247.13247.2 1.99E-05 18-Nov K.FPLTTESAMK[136.11].K "sp|P62750|RL23A_HUMAN,tr|H7BY10|H7BY10_HUMAN,tr|K7ERT8|K7ERT8_HUMAN,tr|A8MUS3|A8MUS3_HUMAN,tr|K7EJV9|K7EJV9_HUMAN" 5 1131.5725 0.63 13632 13247 2 1131.572838 566.7935 60S ribosomal protein L23a OS=Homo sapiens OX=9606 GN=RPL23A PE=1 SV=1 6 2747.9 - 2.21E+06 - - - 0.2572 - 2.105 0.459 - 475.2 1 2 0 0.0003 10 0 0 0 4.05E+07 6.47E+07 - - - 4.5087 0.9994 221125_WJC_METTL3_EV_vs_WT_F02.13252.13252.2 0.0211 18-Sep K.LSPELLNTGR[166.11].F "sp|P52789|HXK2_HUMAN,tr|E9PB90|E9PB90_HUMAN" 2 1108.6116 3.27 13635 13252 2 1108.611371 555.3131 Hexokinase-2 OS=Homo sapiens OX=9606 GN=HK2 PE=1 SV=2 6 2748.6 - 487883 - - - -0.2003 - 1.693 0.306 - 250.6 1 2 0 -0.0002 10 0 0 0 1.03E+08 3.15E+07 - - - 2.7707 0.9999 221125_WJC_METTL3_EV_vs_WT_F02.13255.13255.2 7.78E-05 20-Dec R.NPEAALSPTFR[166.11].S "sp|Q86U44|MTA70_HUMAN,tr|B4E349|B4E349_HUMAN,tr|F5H6D8|F5H6D8_HUMAN,tr|B4DTN4|B4DTN4_HUMAN" 4 1211.6174 0.01 13637 13255 2 1211.617843 606.816 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 6 2748.9 - 983484 - - - 0.3598 - 2.575 0.53 - 789.9 1 2 0 0.0004 11 0 0 0 4.29E+05 2.95E+07 - - - 5.5142 0.9996 221125_WJC_METTL3_EV_vs_WT_F02.13257.13257.2 0.00916 14-Sep K.VFAVLNEK.T "sp|Q15643|TRIPB_HUMAN,tr|H0YJ97|H0YJ97_HUMAN" 2 918.5175 1.14 13638 13257 2 918.518215 460.266 Thyroid receptor-interacting protein 11 OS=Homo sapiens OX=9606 GN=TRIP11 PE=1 SV=3 5.97 2749.1 - 5.69E+06 - - - 0.8133 - 1.799 0.368 - 308.9 1 2 0 0.0007 8 0 0 0 3.46E+08 3.02E+08 - - - 3.5299 0.9967 221125_WJC_METTL3_EV_vs_WT_F02.13259.13259.2 0.0239 16-May R.VVAC[160.03]FDSLK[136.11].G "sp|Q9NUK0|MBNL3_HUMAN,tr|B1AKI6|B1AKI6_HUMAN" 2 1045.5358 1.23 13640 13259 2 1045.537727 523.7752 Muscleblind-like protein 3 OS=Homo sapiens OX=9606 GN=MBNL3 PE=1 SV=2 5.8 2749.3 - 983454 - - - 1.8746 - 1.219 0.342 - 68.1 2 2 0 0.002 9 0 0 0 3.14E+07 2.54E+07 - - - 2.0048 0.9967 221125_WJC_METTL3_EV_vs_WT_F02.13262.13262.2 0.135 18-Jun K.VLLPEYGGTK[136.11].V "sp|P61604|CH10_HUMAN,tr|B8ZZ54|B8ZZ54_HUMAN,tr|B8ZZL8|B8ZZL8_HUMAN" 3 1083.6056 1.91 13641 13262 2 1083.605439 542.8101 "10 kDa heat shock protein, mitochondrial OS=Homo sapiens OX=9606 GN=HSPE1 PE=1 SV=2" 5.97 2749.7 - 3.90E+06 - - - -0.1126 - 1.271 0.23 - 113.2 1 2 0 -0.0001 10 0 0 0 2.15E+08 1.13E+08 - - - 1.4091 0.9996 221125_WJC_METTL3_EV_vs_WT_F02.13264.13264.2 0.0107 16-Sep K.QLADETLLK[136.11].V "sp|P20700|LMNB1_HUMAN,tr|E9PBF6|E9PBF6_HUMAN,tr|A0A0D9SFE5|A0A0D9SFE5_HUMAN" 3 1037.5848 0.96 13642 13264 2 1037.585721 519.7997 Lamin-B1 OS=Homo sapiens OX=9606 GN=LMNB1 PE=1 SV=2 4.37 2749.9 - 3.48E+06 - - - 0.8626 - 1.794 0.371 - 334.9 1 2 0 0.0009 9 0 0 0 2.06E+08 2.14E+08 - - - 3.4718 0.9997 221125_WJC_METTL3_EV_vs_WT_F02.13266.13266.2 0.00149 14-Jul R.TFEVTPIR[166.11].A "sp|Q14739|LBR_HUMAN,tr|A0A494C1L1|A0A494C1L1_HUMAN,tr|C9JXK0|C9JXK0_HUMAN" 3 971.5316 1.09 13644 13266 2 971.53101 486.7731 Delta(14)-sterol reductase LBR OS=Homo sapiens OX=9606 GN=LBR PE=1 SV=2 5.66 2750.1 - 6.39E+06 - - - -0.5579 - 1.341 0.481 - 159 1 2 0 -0.0005 8 0 0 0 1.70E+08 1.56E+08 - - - 3.4784 0.996 221125_WJC_METTL3_EV_vs_WT_F02.13267.13267.2 0.0953 14-Jul R.QAVPLFSK.N "sp|Q9BZZ5|API5_HUMAN,tr|G3V1C3|G3V1C3_HUMAN" 2 888.5069 2.8 13645 13267 2 888.507484 445.2607 Apoptosis inhibitor 5 OS=Homo sapiens OX=9606 GN=API5 PE=1 SV=3 8.75 2750.1 - 2.79E+06 - - - 0.6539 - 1.501 0.148 - 167 1 2 0 0.0006 8 0 0 0 1.44E+08 5.16E+07 - - - 1.3588 0.9999 221125_WJC_METTL3_EV_vs_WT_F02.13277.13277.2 2.27E-05 24-Nov R.FSGSGSGTDFTLK.L "sp|A2NJV5|KV229_HUMAN,sp|A0A087WW87|KV240_HUMAN,sp|P06310|KV230_HUMAN,sp|A0A075B6S2|KVD29_HUMAN,sp|P01614|KVD40_HUMAN,sp|P01615|KVD28_HUMAN,sp|A0A075B6S6|KVD30_HUMAN,sp|A0A075B6P5|KV228_HUMAN,sp|A0A0A0MRZ7|KVD26_HUMAN" 9 1302.6092 178.66 13652 13277 2 1302.607552 652.3119 Immunoglobulin kappa variable 2-29 OS=Homo sapiens OX=9606 GN=IGKV2-29 PE=3 SV=2 5.84 2751.3 - 295569 - - - -1.2621 - 2.356 0.567 - 254.7 1 2 0 -0.0016 13 0 0 0 2.75E+07 1.54E+05 - - - 5.4278 0.9999 221125_WJC_METTL3_EV_vs_WT_F02.13279.13279.2 3.78E-05 20-Dec K.LSAMMGAVAEK[136.11].K "sp|Q86U44|MTA70_HUMAN,tr|F5H6D8|F5H6D8_HUMAN,tr|H0YFV6|H0YFV6_HUMAN,tr|B4DTN4|B4DTN4_HUMAN" 4 1114.5606 0.01 13653 13279 2 1114.561719 558.2876 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 6 2751.5 - 4.05E+06 - - - 1.0022 - 2.454 0.567 - 450.4 1 2 0 0.0011 11 0 0 0 9.23E+05 1.18E+08 - - - 5.6571 0.9885 221125_WJC_METTL3_EV_vs_WT_F02.13281.13281.2 0.0556 14-Aug R.EPVLAQLR[166.11].G "sp|Q6P2E9|EDC4_HUMAN,tr|I3L2F4|I3L2F4_HUMAN" 2 934.5475 2.93 13655 13281 2 934.550511 468.281 Enhancer of mRNA-decapping protein 4 OS=Homo sapiens OX=9606 GN=EDC4 PE=1 SV=1 6.1 2751.6 - 585519 - - - 3.1834 - 1.5 0.196 - 217.7 1 2 0 0.003 8 0 0 0 9.51E+07 3.25E+07 - - - 1.7106 0.9988 221125_WJC_METTL3_EV_vs_WT_F02.13282.13282.2 0.00412 16-Aug R.IGSTIFGER[166.11].D sp|O94903|PLPHP_HUMAN 1 988.5217 0.5 13656 13282 2 988.523217 495.2681 Pyridoxal phosphate homeostasis protein OS=Homo sapiens OX=9606 GN=PLPBP PE=1 SV=1 6 2751.7 - 547058 - - - 1.5194 - 1.737 0.277 - 119.6 1 2 0 0.0015 9 0 0 0 7.42E+06 1.47E+07 - - - 2.6839 0.8249 221125_WJC_METTL3_EV_vs_WT_F02.13283.13283.2 0.00618 12-Jul E.ILDLIHK[136.11].V "sp|O14981|BTAF1_HUMAN,sp|O00443|P3C2A_HUMAN,tr|A0A0A0MTH9|A0A0A0MTH9_HUMAN" 3 858.5418 1.54 13657 13283 2 858.542303 430.2782 TATA-binding protein-associated factor 172 OS=Homo sapiens OX=9606 GN=BTAF1 PE=1 SV=2 6.74 2751.8 - 439808 - - - 0.5405 - 1.414 0.175 - 115.2 1 1 0 0.0005 7 0 0 0 2.26E+07 1.47E+07 - - - 1.4311 0.9981 221125_WJC_METTL3_EV_vs_WT_F02.13284.13284.3 1.13E-09 17/72 K.PSTASAVPELATDPELEK[136.11]K[136.11].L "sp|Q86U44|MTA70_HUMAN,tr|B4E349|B4E349_HUMAN,tr|F5H6D8|F5H6D8_HUMAN,tr|H0YFV6|H0YFV6_HUMAN,tr|B4DTN4|B4DTN4_HUMAN" 5 1998.0492 0.001 13658 13284 3 1998.050864 667.0237 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 4.41 2751.9 - 188627 - - - 0.8318 - 2.61 0.571 - 212.5 1 1 0 0.0017 19 0 0 0 0.00E+00 8.83E+06 - - - 7.2626 0.9988 221125_WJC_METTL3_EV_vs_WT_F02.13288.13288.2 0.124 18-Oct K.GAVAIADAIR[166.11].G "sp|P46060|RAGP1_HUMAN,tr|H0Y4Q3|H0Y4Q3_HUMAN" 2 965.5534 1.99 13660 13288 2 965.552356 483.784 Ran GTPase-activating protein 1 OS=Homo sapiens OX=9606 GN=RANGAP1 PE=1 SV=1 5.84 2752.5 - 3.02E+06 - - - -1.0295 - 2.007 0.184 - 439.2 1 2 0 -0.001 10 0 0 0 1.91E+08 9.60E+07 - - - 2.3442 0.7973 221125_WJC_METTL3_EV_vs_WT_F02.13289.13289.2 0.233 14-Jun R.LENEIQTY.R "sp|P13645|K1C10_HUMAN,tr|A0A1B0GVI3|A0A1B0GVI3_HUMAN" 2 1008.4764 - 13661 13289 2 1008.47666 505.2455 "Keratin, type I cytoskeletal 10 OS=Homo sapiens OX=9606 GN=KRT10 PE=1 SV=6" 3.79 2752.5 - 1.56E+06 - - - 0.2667 - 1.361 0.173 - 133.5 1 1 0 0.0003 8 0 0 0 - - - - - 1.2483 0.9994 221125_WJC_METTL3_EV_vs_WT_F02.13290.13290.2 0.00159 14-Jul R.LTPEDFAR[166.11].A "sp|Q9NP79|VTA1_HUMAN,tr|Q5TGM0|Q5TGM0_HUMAN,tr|A0A087WY55|A0A087WY55_HUMAN" 3 957.4795 1.5 13662 13290 2 957.480149 479.747 Vacuolar protein sorting-associated protein VTA1 homolog OS=Homo sapiens OX=9606 GN=VTA1 PE=1 SV=1 4.37 2752.6 - 5.88E+06 - - - 0.6611 - 1.424 0.38 - 261.1 1 2 0 0.0006 8 0 0 0 8.05E+08 5.36E+08 - - - 2.9135 0.9965 221125_WJC_METTL3_EV_vs_WT_F02.13292.13292.2 0.0161 14-Aug K.SLGLLTTK.F "sp|Q16254|E2F4_HUMAN,sp|Q15329|E2F5_HUMAN,tr|H3BTM3|H3BTM3_HUMAN,tr|H3BVE4|H3BVE4_HUMAN,tr|H3BMP3|H3BMP3_HUMAN" 5 831.5066 1.81 13664 13292 2 831.50619 416.7606 Transcription factor E2F4 OS=Homo sapiens OX=9606 GN=E2F4 PE=1 SV=2 8.47 2752.7 - 1.12E+06 - - - -0.4558 - 1.248 0.226 - 175.2 1 2 0 -0.0004 8 0 0 0 5.78E+07 3.20E+07 - - - 1.3783 0.9984 221125_WJC_METTL3_EV_vs_WT_F02.13294.13294.2 0.0463 18-Aug R.TMLYTPQEMK[136.11].Q "sp|Q9Y265|RUVB1_HUMAN,tr|E7ETR0|E7ETR0_HUMAN,tr|H7C4G5|H7C4G5_HUMAN,tr|J3QLR1|J3QLR1_HUMAN" 4 1248.5974 0.78 13666 13294 2 1248.59438 625.306 RuvB-like 1 OS=Homo sapiens OX=9606 GN=RUVBL1 PE=1 SV=1 5.66 2753 - 338136 - - - -2.4035 - 1.493 0.373 - 190.3 1 2 0 -0.003 10 0 0 0 1.31E+07 1.69E+07 - - - 2.9138 0.9945 221125_WJC_METTL3_EV_vs_WT_F02.13298.13298.2 0.276 14-Jul K.TIIGDFQK[136.11].E sp|Q96A49|SYAP1_HUMAN 1 928.5109 1.23 13668 13298 2 928.510206 465.2627 Synapse-associated protein 1 OS=Homo sapiens OX=9606 GN=SYAP1 PE=1 SV=1 5.5 2753.5 - 2.07E+07 - - - -0.783 - 1.267 0.182 - 126.8 1 2 0 -0.0007 8 0 0 0 5.98E+09 4.87E+09 - - - 1.0988 0.9937 221125_WJC_METTL3_EV_vs_WT_F02.13299.13299.2 1.08 14-Jul K.TIIGDFQK.E sp|Q96A49|SYAP1_HUMAN 1 920.4967 1.23 13669 13299 2 920.496148 461.2556 Synapse-associated protein 1 OS=Homo sapiens OX=9606 GN=SYAP1 PE=1 SV=1 5.5 2753.5 - 2.01E+07 - - - -0.6355 - 1.374 0.133 - 129.1 1 2 0 -0.0006 8 0 0 0 5.97E+09 4.87E+09 - - - 0.9814 0.9995 221125_WJC_METTL3_EV_vs_WT_F02.13300.13300.2 0.0132 16-Sep K.GGPLQALTR.E sp|P42167|LAP2B_HUMAN 1 911.5189 2.49 13670 13300 2 911.520065 456.7667 "Lamina-associated polypeptide 2, isoforms beta\gamma OS=Homo sapiens OX=9606 GN=TMPO PE=1 SV=2" 9.75 2753.6 - 1.68E+06 - - - 1.3165 - 1.692 0.403 - 315.2 1 2 0 0.0012 9 0 0 0 1.90E+08 7.65E+07 - - - 3.5387 0.9998 221125_WJC_METTL3_EV_vs_WT_F02.13306.13306.2 2.72E-05 18-Aug R.VPSSLAYSLK[136.11].K sp|Q9NQS7|INCE_HUMAN 1 1071.6056 1.39 13674 13306 2 1071.605788 536.8101 Inner centromere protein OS=Homo sapiens OX=9606 GN=INCENP PE=1 SV=3 8.56 2754.4 - 2.09E+06 - - - 0.2118 - 1.83 0.473 - 214.9 1 2 0 0.0002 10 0 0 0 1.36E+08 9.85E+07 - - - 4.2213 0.987 221125_WJC_METTL3_EV_vs_WT_F02.13310.13310.2 0.468 12-Jun R.LLSVNIR.V sp|P07814|SYEP_HUMAN 1 813.5072 0.8 13677 13310 2 813.507496 407.7609 Bifunctional glutamate\proline--tRNA ligase OS=Homo sapiens OX=9606 GN=EPRS1 PE=1 SV=5 9.75 2754.8 - 1.19E+06 - - - 0.3171 - 1.039 0.177 - 96.6 1 2 0 0.0003 7 0 0 0 5.31E+07 6.61E+07 - - - 0.4695 0.9968 221125_WJC_METTL3_EV_vs_WT_F02.13319.13319.2 0.514 12-Jul R.IGTFDLK[136.11].Y "sp|Q14739|LBR_HUMAN,tr|A0A494C1L1|A0A494C1L1_HUMAN" 2 800.4524 0.89 13682 13319 2 800.452594 401.2335 Delta(14)-sterol reductase LBR OS=Homo sapiens OX=9606 GN=LBR PE=1 SV=2 5.84 2756 - 687538 - - - 0.2986 - 1.327 0.204 - 103.8 1 2 0 0.0002 7 0 0 0 1.62E+07 1.82E+07 - - - 1.4441 0.9929 221125_WJC_METTL3_EV_vs_WT_F02.13320.13320.2 0.0247 12-May R.DASLVFK.V "sp|P61221|ABCE1_HUMAN,tr|D6R9I9|D6R9I9_HUMAN" 2 778.4225 0.37 13683 13320 2 778.421447 390.2185 ATP-binding cassette sub-family E member 1 OS=Homo sapiens OX=9606 GN=ABCE1 PE=1 SV=1 5.84 2756.1 - 637277 - - - -1.3592 - 1.258 0.199 - 74.7 2 2 0 -0.0011 7 0 0 0 3.29E+07 8.77E+07 - - - 1.1033 0.9908 221125_WJC_METTL3_EV_vs_WT_F02.13323.13323.2 0.00223 16-Nov R.PLISVYSEK.G "sp|P36578|RL4_HUMAN,tr|H3BTP7|H3BTP7_HUMAN,tr|H3BU31|H3BU31_HUMAN" 3 1034.5648 0.57 13685 13323 2 1034.56544 518.2897 60S ribosomal protein L4 OS=Homo sapiens OX=9606 GN=RPL4 PE=1 SV=5 6.42 2756.5 - 8.42E+06 - - - 0.607 - 1.992 0.489 - 460.8 1 1 0 0.0006 9 0 0 0 2.21E+08 3.90E+08 - - - 4.6463 0.9997 221125_WJC_METTL3_EV_vs_WT_F02.13324.13324.2 0.0151 14-Sep R.QILELEER.H sp|Q16352|AINX_HUMAN 1 1028.5502 1.54 13686 13324 2 1028.549965 515.2824 Alpha-internexin OS=Homo sapiens OX=9606 GN=INA PE=1 SV=2 4.25 2756.5 - 5.99E+06 - - - -0.2528 - 2.003 0.335 - 449.9 1 2 0 -0.0003 8 0 0 0 1.46E+08 9.44E+07 - - - 3.6102 0.9933 221125_WJC_METTL3_EV_vs_WT_F02.13326.13326.2 0.124 12-Jun K.IPNFDVR.E sp|P11388|TOP2A_HUMAN 1 859.4552 1.05 13688 13326 2 859.456509 430.7349 DNA topoisomerase 2-alpha OS=Homo sapiens OX=9606 GN=TOP2A PE=1 SV=3 5.84 2756.7 - 763420 - - - 1.5207 - 1.292 0.195 - 99 1 2 0 0.0013 7 0 0 0 5.69E+07 5.41E+07 - - - 1.2926 0.9997 221125_WJC_METTL3_EV_vs_WT_F02.13327.13327.2 0.0019 22-Oct K.IDDMTAAPMDVR[166.11].Q "sp|P15927|RFA2_HUMAN,tr|Q5TEJ7|Q5TEJ7_HUMAN" 2 1343.6089 1.26 13689 13327 2 1343.606793 672.8117 Replication protein A 32 kDa subunit OS=Homo sapiens OX=9606 GN=RPA2 PE=1 SV=1 3.93 2756.9 - 414933 - - - -1.5622 - 1.98 0.456 - 202.4 1 2 0 -0.0021 12 0 0 0 1.89E+08 1.49E+08 - - - 4.2057 0.9988 221125_WJC_METTL3_EV_vs_WT_F02.13330.13330.2 0.0456 16-Aug R.IDISPSTLR[166.11].K "sp|Q9NYF8|BCLF1_HUMAN,tr|E9PKI6|E9PKI6_HUMAN,tr|A0A1W2PQ43|A0A1W2PQ43_HUMAN,tr|E9PK91|E9PK91_HUMAN,tr|E9PK09|E9PK09_HUMAN,tr|E9PQN2|E9PQN2_HUMAN" 6 1010.5636 2.06 13690 13330 2 1010.564556 506.2891 Bcl-2-associated transcription factor 1 OS=Homo sapiens OX=9606 GN=BCLAF1 PE=1 SV=2 5.84 2757.2 - 3.55E+06 - - - 0.9658 - 1.67 0.258 - 142 1 2 0 0.001 9 0 0 0 2.47E+09 1.20E+09 - - - 2.4299 0.9998 221125_WJC_METTL3_EV_vs_WT_F02.13332.13332.2 3.67E-05 18-Nov R.VPSSLAYSLK.K sp|Q9NQS7|INCE_HUMAN 1 1063.5914 1.39 13692 13332 2 1063.590291 532.803 Inner centromere protein OS=Homo sapiens OX=9606 GN=INCENP PE=1 SV=3 8.56 2757.4 - 4.22E+06 - - - -1.006 - 2.103 0.424 - 415.4 1 2 0 -0.0011 10 0 0 0 1.36E+08 9.85E+07 - - - 4.2473 0.9971 221125_WJC_METTL3_EV_vs_WT_F02.13335.13335.2 0.0251 16-Sep R.AAVIGDVIR.V sp|Q9NR30|DDX21_HUMAN 1 912.5393 1.13 13693 13335 2 912.541986 457.2769 Nucleolar RNA helicase 2 OS=Homo sapiens OX=9606 GN=DDX21 PE=1 SV=5 5.88 2757.8 - 3.08E+06 - - - 2.9807 - 1.883 0.258 - 354.8 1 2 0 0.0027 9 0 0 0 2.28E+08 2.01E+08 - - - 2.7766 0.9644 221125_WJC_METTL3_EV_vs_WT_F02.13341.13341.2 0.0954 14-Jul K.ALETVFGK.Y "sp|Q96E39|RMXL1_HUMAN,tr|A0A1B0GUK8|A0A1B0GUK8_HUMAN" 2 863.4753 0.66 13698 13341 2 863.475326 432.7449 "RNA binding motif protein, X-linked-like-1 OS=Homo sapiens OX=9606 GN=RBMXL1 PE=1 SV=1" 6.05 2758.5 - 794511 - - - 0.066 - 1.258 0.007 - 163.8 1 2 0 0.0001 8 0 0 0 8.20E+07 1.24E+08 - - - -0.2151 0.9905 221125_WJC_METTL3_EV_vs_WT_F02.13344.13344.2 0.527 16-Dec K.TLLAQTLAK[136.11].C sp|O76031|CLPX_HUMAN 1 965.6001 1.36 13699 13344 2 965.597566 483.8073 "ATP-dependent Clp protease ATP-binding subunit clpX-like, mitochondrial OS=Homo sapiens OX=9606 GN=CLPX PE=1 SV=2" 8.41 2758.9 - 1.49E+06 - - - -2.6056 - 1.564 0.16 - 357.1 1 2 0 -0.0025 9 0 0 0 5.76E+07 4.22E+07 - - - 1.5159 0.9998 221125_WJC_METTL3_EV_vs_WT_F02.13345.13345.2 1.32E-05 22-Oct K.IDDMTAAPMDVR.Q "sp|P15927|RFA2_HUMAN,tr|Q5TEJ7|Q5TEJ7_HUMAN" 2 1333.6006 1.26 13700 13345 2 1333.599178 667.8076 Replication protein A 32 kDa subunit OS=Homo sapiens OX=9606 GN=RPA2 PE=1 SV=1 3.93 2759 - 1.44E+06 - - - -1.0828 - 2.27 0.487 - 359.7 1 2 0 -0.0014 12 0 0 0 1.89E+08 1.49E+08 - - - 4.7945 0.9997 221125_WJC_METTL3_EV_vs_WT_F02.13346.13346.2 0.0024 18-Oct R.GIYPSETFTR[166.11].V sp|Q13257|MD2L1_HUMAN 1 1179.58 1.56 13701 13346 2 1179.578905 590.7973 Mitotic spindle assembly checkpoint protein MAD2A OS=Homo sapiens OX=9606 GN=MAD2L1 PE=1 SV=1 6 2759.1 - 1.58E+06 - - - -0.8927 - 1.659 0.442 - 249.7 1 2 0 -0.0011 10 0 0 0 1.63E+08 1.05E+08 - - - 3.7183 0.9932 221125_WJC_METTL3_EV_vs_WT_F02.13348.13348.2 0.32 14-Aug R.VVNLLQER[166.11].N sp|O95486|SC24A_HUMAN 1 979.569 1.01 13703 13348 2 979.565978 490.7918 Protein transport protein Sec24A OS=Homo sapiens OX=9606 GN=SEC24A PE=1 SV=2 5.97 2759.4 - 801326 - - - -3.085 - 1.676 0.198 - 147.2 1 2 0 -0.003 8 0 0 0 2.75E+07 2.73E+07 - - - 2.0599 0.9996 221125_WJC_METTL3_EV_vs_WT_F02.13349.13349.2 0.00142 18-Oct R.TMLYTPQEMK.Q "sp|Q9Y265|RUVB1_HUMAN,tr|E7ETR0|E7ETR0_HUMAN,tr|H7C4G5|H7C4G5_HUMAN,tr|J3QLR1|J3QLR1_HUMAN" 4 1240.5832 0.75 13704 13349 2 1240.584355 621.2989 RuvB-like 1 OS=Homo sapiens OX=9606 GN=RUVBL1 PE=1 SV=1 5.66 2759.5 - 0 - - - 0.9463 - 1.642 0.43 - 281.8 1 2 0 0.0012 10 0 0 0 1.31E+07 1.75E+07 - - - 3.6009 0.9995 221125_WJC_METTL3_EV_vs_WT_F02.13352.13352.2 7.70E-05 18-Nov R.GIYPSETFTR.V sp|Q13257|MD2L1_HUMAN 1 1169.5717 1.66 13705 13352 2 1169.569041 585.7931 Mitotic spindle assembly checkpoint protein MAD2A OS=Homo sapiens OX=9606 GN=MAD2L1 PE=1 SV=1 6 2759.9 - 3.42E+06 - - - -2.2632 - 1.747 0.497 - 311.4 1 2 0 -0.0026 10 0 0 0 1.76E+08 1.06E+08 - - - 4.2683 0.9997 221125_WJC_METTL3_EV_vs_WT_F02.13353.13353.3 3.30E-06 13/36 R.LFFAGEHTIR[166.11].N "sp|O60341|KDM1A_HUMAN,tr|R4GMQ1|R4GMQ1_HUMAN,tr|R4GMP9|R4GMP9_HUMAN" 3 1199.6327 1.51 13706 13353 3 1199.630403 400.8848 Lysine-specific histone demethylase 1A OS=Homo sapiens OX=9606 GN=KDM1A PE=1 SV=2 6.75 2760 - 1.50E+06 - - - -1.8839 - 2.489 0.315 - 186.7 1 2 0 -0.0023 10 0 0 0 8.34E+07 5.53E+07 - - - 4.7144 0.9472 221125_WJC_METTL3_EV_vs_WT_F02.13354.13354.2 14 12-Jul K.GLEELVK.Q "sp|O75369|FLNB_HUMAN,tr|E7EN95|E7EN95_HUMAN,tr|A0A804HK76|A0A804HK76_HUMAN,tr|A0A804HL72|A0A804HL72_HUMAN" 4 786.4487 1.17 13707 13354 2 786.449329 394.2316 Filamin-B OS=Homo sapiens OX=9606 GN=FLNB PE=1 SV=2 4.53 2760.1 - 1.42E+06 - - - 0.7744 - 1.111 0.036 - 145.6 1 2 0 0.0006 7 0 0 0 4.65E+07 3.97E+07 - - - -0.3598 0.9998 221125_WJC_METTL3_EV_vs_WT_F02.13359.13359.3 0.0742 13/36 R.LFFAGEHTIR.N "sp|O60341|KDM1A_HUMAN,tr|R4GMQ1|R4GMQ1_HUMAN,tr|R4GMP9|R4GMP9_HUMAN" 3 1189.6244 1.51 13709 13359 3 1189.623894 397.5487 Lysine-specific histone demethylase 1A OS=Homo sapiens OX=9606 GN=KDM1A PE=1 SV=2 6.75 2760.7 - 2.61E+06 - - - -0.4195 - 2.474 0.315 - 218.9 1 2 0 -0.0005 10 0 0 0 8.34E+07 5.53E+07 - - - 4.6972 0.9994 221125_WJC_METTL3_EV_vs_WT_F02.13363.13363.2 0.369 18-Sep R.ALQSPALGLR.G "sp|P46940|IQGA1_HUMAN,tr|A0A0J9YXZ5|A0A0J9YXZ5_HUMAN" 2 1024.6029 0.96 13710 13363 2 1024.602882 513.3087 Ras GTPase-activating-like protein IQGAP1 OS=Homo sapiens OX=9606 GN=IQGAP1 PE=1 SV=1 9.79 2761.2 - 1.69E+06 - - - -0.0459 - 1.998 0.26 - 282.4 1 2 0 0 10 0 0 0 7.99E+07 8.31E+07 - - - 2.8933 0.9974 221125_WJC_METTL3_EV_vs_WT_F02.13365.13365.2 0.947 12-Jul K.FASFIDK.V "sp|Q86Y46|K2C73_HUMAN,sp|Q7RTS7|K2C74_HUMAN,sp|Q9NSB2|KRT84_HUMAN,sp|P48668|K2C6C_HUMAN,sp|Q3SY84|K2C71_HUMAN,sp|P05787|K2C8_HUMAN,sp|Q01546|K22O_HUMAN,sp|P19013|K2C4_HUMAN,sp|Q7Z794|K2C1B_HUMAN,sp|Q8N1N4|K2C78_HUMAN,sp|P12035|K2C3_HUMAN,sp|P04264|K2C1_HUMAN,sp|P04259|K2C6B_HUMAN,sp|P13647|K2C5_HUMAN,sp|P35908|K22E_HUMAN,sp|Q14CN4|K2C72_HUMAN,sp|P08729|K2C7_HUMAN,sp|O95678|K2C75_HUMAN,sp|Q5XKE5|K2C79_HUMAN,sp|P02538|K2C6A_HUMAN,tr|F8VUG2|F8VUG2_HUMAN,tr|F8W0C6|F8W0C6_HUMAN,tr|F8W1U3|F8W1U3_HUMAN,tr|H0YHD9|H0YHD9_HUMAN,tr|F8W1S1|F8W1S1_HUMAN,tr|F8VS61|F8VS61_HUMAN" 26 826.4225 261.18 13711 13365 2 826.422223 414.2185 "Keratin, type II cytoskeletal 73 OS=Homo sapiens OX=9606 GN=KRT73 PE=1 SV=1" 5.84 2761.5 - 1.52E+09 - - - -0.3412 - 1.584 0.149 - 135.4 1 2 0 -0.0003 7 0 0 0 5.17E+10 1.98E+08 - - - 1.5988 0.9969 221125_WJC_METTL3_EV_vs_WT_F02.13366.13366.2 0.026 12-Jun K.DYSPYFK.T "sp|P02533|K1C14_HUMAN,sp|P08779|K1C16_HUMAN" 2 918.4123 525.49 13712 13366 2 918.410875 460.2134 "Keratin, type I cytoskeletal 14 OS=Homo sapiens OX=9606 GN=KRT14 PE=1 SV=4" 5.83 2761.5 - 1.90E+08 - - - -1.5886 - 1.083 0.345 - 142.1 1 2 0 -0.0015 7 0 0 0 1.13E+10 2.16E+07 - - - 1.8414 0.9942 221125_WJC_METTL3_EV_vs_WT_F02.13369.13369.2 0.0513 16-Oct K.VLDAIIQEK[136.11].K "sp|Q9NTJ3|SMC4_HUMAN,tr|E9PD53|E9PD53_HUMAN" 2 1035.6056 0.53 13713 13369 2 1035.605401 518.8101 Structural maintenance of chromosomes protein 4 OS=Homo sapiens OX=9606 GN=SMC4 PE=1 SV=2 4.37 2761.9 - 3.01E+06 - - - -0.1545 - 1.734 0.067 - 243.6 2 2 0 -0.0002 9 0 0 0 6.61E+07 1.24E+08 - - - 0.9938 0.9925 221125_WJC_METTL3_EV_vs_WT_F02.13371.13371.2 0.000833 16-Oct R.MTVEYVYER.M sp|O15226|NKRF_HUMAN 1 1188.5485 1.32 13715 13371 2 1188.543543 595.2815 NF-kappa-B-repressing factor OS=Homo sapiens OX=9606 GN=NKRF PE=1 SV=2 4.53 2762.1 - 1.80E+06 - - - -4.179 - 1.639 0.299 - 431.7 1 2 0 -0.005 9 0 0 0 5.68E+07 4.31E+07 - - - 2.6773 0.9695 221125_WJC_METTL3_EV_vs_WT_F02.13373.13373.2 9.66E-05 20-Nov V.PVPPLPEYGGK[136.11].V sp|P24539|AT5F1_HUMAN 1 1160.6321 1.16 13716 13373 2 1160.629007 581.3233 "ATP synthase F(0) complex subunit B1, mitochondrial OS=Homo sapiens OX=9606 GN=ATP5PB PE=1 SV=2" 6.42 2762.4 - 3.33E+06 - - - -2.6735 - 1.822 0.521 - 417.9 1 1 0 -0.0031 11 0 0 0 2.12E+08 1.83E+08 - - - 4.5111 0.7797 221125_WJC_METTL3_EV_vs_WT_F02.13375.13375.2 2.76 18-Jul R.IINEGAAILR[166.11].R "sp|P16298|PP2BB_HUMAN,tr|Q5F2F8|Q5F2F8_HUMAN" 2 1078.6374 0.9 13717 13375 2 1078.633576 540.326 Serine\threonine-protein phosphatase 2B catalytic subunit beta isoform OS=Homo sapiens OX=9606 GN=PPP3CB PE=1 SV=2 6 2762.6 - 0 - - - -3.5582 - 1.233 0.011 - 88.6 1 2 0 -0.0038 10 0 0 0 3.92E+06 4.34E+06 - - - -0.2943 0.9994 221125_WJC_METTL3_EV_vs_WT_F02.13377.13377.2 0.0184 14-Jun K.EFTNVYIK[136.11].N "sp|Q13310|PABP4_HUMAN,sp|P11940|PABP1_HUMAN,sp|P0CB38|PAB4L_HUMAN,tr|A0A7I2V5W9|A0A7I2V5W9_HUMAN,tr|A0A7I2YQE4|A0A7I2YQE4_HUMAN,tr|A0A7I2V649|A0A7I2V649_HUMAN,tr|B1ANR0|B1ANR0_HUMAN,tr|A0A7I2V4L7|A0A7I2V4L7_HUMAN,tr|H0YCC8|H0YCC8_HUMAN,tr|H0YAR2|H0YAR2_HUMAN,tr|E7ERJ7|E7ERJ7_HUMAN,tr|A0A7I2V598|A0A7I2V598_HUMAN,tr|A0A7I2YQ88|A0A7I2YQ88_HUMAN,tr|H0Y5F5|H0Y5F5_HUMAN,tr|H0YBN4|H0YBN4_HUMAN,tr|A0A087WTT1|A0A087WTT1_HUMAN,tr|A0A7I2YQ90|A0A7I2YQ90_HUMAN,tr|A0A7I2V4N4|A0A7I2V4N4_HUMAN,tr|E7EQV3|E7EQV3_HUMAN" 19 1020.5371 1.26 13718 13377 2 1020.536436 511.2758 Polyadenylate-binding protein 4 OS=Homo sapiens OX=9606 GN=PABPC4 PE=1 SV=1 6.1 2762.8 - 2.26E+06 - - - -0.6967 - 1.478 0.359 - 194.9 1 2 0 -0.0007 8 0 0 0 1.04E+09 8.27E+08 - - - 2.8707 0.9983 221125_WJC_METTL3_EV_vs_WT_F02.13382.13382.2 3.70E-06 18-Oct K.QYGNEVFLAK[136.11].L "sp|P50990|TCPQ_HUMAN,tr|H7C4C8|H7C4C8_HUMAN" 2 1175.6066 0.36 13721 13382 2 1175.611077 588.8106 T-complex protein 1 subunit theta OS=Homo sapiens OX=9606 GN=CCT8 PE=1 SV=4 6 2763.4 - 3.85E+06 - - - 3.7878 - 1.751 0.468 - 369.8 1 2 0 0.0045 10 0 0 0 2.60E+08 7.24E+08 - - - 4.0599 0.9996 221125_WJC_METTL3_EV_vs_WT_F02.13383.13383.2 0.00741 16-Sep K.VLDAIIQEK.K "sp|Q9NTJ3|SMC4_HUMAN,tr|E9PD53|E9PD53_HUMAN" 2 1027.5914 0.56 13722 13383 2 1027.590085 514.803 Structural maintenance of chromosomes protein 4 OS=Homo sapiens OX=9606 GN=SMC4 PE=1 SV=2 4.37 2763.5 - 1.89E+06 - - - -1.2417 - 1.88 0.355 - 199.8 1 2 0 -0.0013 9 0 0 0 6.61E+07 1.17E+08 - - - 3.4889 0.999 221125_WJC_METTL3_EV_vs_WT_F02.13389.13389.2 0.00343 12-Jul R.DPVLTLR.A sp|Q86XL3|ANKL2_HUMAN 1 812.4756 1.74 13724 13389 2 812.474781 407.2451 Ankyrin repeat and LEM domain-containing protein 2 OS=Homo sapiens OX=9606 GN=ANKLE2 PE=1 SV=4 5.84 2764.3 - 1.14E+06 - - - -1.0117 - 1.707 0.247 - 270.7 1 2 0 -0.0008 7 0 0 0 5.27E+07 3.02E+07 - - - 2.5594 0.9992 221125_WJC_METTL3_EV_vs_WT_F02.13390.13390.2 0.21 16-Nov K.ILDDIC[160.03]VAK[136.11].A sp|Q15046|SYK_HUMAN 1 1053.562 0.44 13725 13390 2 1053.559601 527.7883 Lysine--tRNA ligase OS=Homo sapiens OX=9606 GN=KARS1 PE=1 SV=3 4.21 2764.4 - 417224 - - - -2.26 - 2.011 0.343 - 216.3 1 2 0 -0.0024 9 0 0 0 2.76E+07 6.31E+07 - - - 3.5948 0.9797 221125_WJC_METTL3_EV_vs_WT_F02.13391.13391.2 0.208 14-Jul K.QLIDITGK[136.11].N "sp|Q14157|UBP2L_HUMAN,tr|Q5VU78|Q5VU78_HUMAN,tr|F8W726|F8W726_HUMAN,tr|Q5VU81|Q5VU81_HUMAN,tr|Q5VU79|Q5VU79_HUMAN,tr|Q5VU80|Q5VU80_HUMAN,tr|Q5VU77|Q5VU77_HUMAN" 7 894.5266 2.02 13726 13391 2 894.523981 448.2706 Ubiquitin-associated protein 2-like OS=Homo sapiens OX=9606 GN=UBAP2L PE=1 SV=2 5.84 2764.5 - 1.32E+07 - - - -2.9088 - 1.364 0.154 - 173.7 1 2 0 -0.0026 8 0 0 0 1.65E+09 8.16E+08 - - - 1.1138 0.9999 221125_WJC_METTL3_EV_vs_WT_F02.13395.13395.2 0.0446 20-Nov K.LLEISAEDAER.W sp|O95926|SYF2_HUMAN 1 1244.6248 1.89 13728 13395 2 1244.6245 623.3197 Pre-mRNA-splicing factor SYF2 OS=Homo sapiens OX=9606 GN=SYF2 PE=1 SV=1 4 2765 - 910437 - - - -0.278 - 2.222 0.471 - 484 1 2 0 -0.0003 11 0 0 0 3.91E+07 2.07E+07 - - - 4.6796 0.999 221125_WJC_METTL3_EV_vs_WT_F02.13396.13396.2 0.0144 20-Sep K.LLEISAEDAER[166.11].W sp|O95926|SYF2_HUMAN 1 1254.6331 1.9 13729 13396 2 1254.630516 628.3238 Pre-mRNA-splicing factor SYF2 OS=Homo sapiens OX=9606 GN=SYF2 PE=1 SV=1 4 2765.1 - 638359 - - - -2.0723 - 1.931 0.317 - 292.7 1 2 0 -0.0026 11 0 0 0 3.94E+07 2.07E+07 - - - 3.1617 0.884 221125_WJC_METTL3_EV_vs_WT_F02.13399.13399.2 0.34 12-Aug K.FASFIDK[136.11].V "sp|Q86Y46|K2C73_HUMAN,sp|Q7RTS7|K2C74_HUMAN,sp|Q9NSB2|KRT84_HUMAN,sp|P48668|K2C6C_HUMAN,sp|Q3SY84|K2C71_HUMAN,sp|P05787|K2C8_HUMAN,sp|Q01546|K22O_HUMAN,sp|P19013|K2C4_HUMAN,sp|Q7Z794|K2C1B_HUMAN,sp|Q8N1N4|K2C78_HUMAN,sp|P12035|K2C3_HUMAN,sp|P04264|K2C1_HUMAN,sp|P04259|K2C6B_HUMAN,sp|P13647|K2C5_HUMAN,sp|P35908|K22E_HUMAN,sp|Q14CN4|K2C72_HUMAN,sp|P08729|K2C7_HUMAN,sp|O95678|K2C75_HUMAN,sp|Q5XKE5|K2C79_HUMAN,sp|P02538|K2C6A_HUMAN,tr|F8VUG2|F8VUG2_HUMAN,tr|F8W0C6|F8W0C6_HUMAN,tr|F8W1U3|F8W1U3_HUMAN,tr|H0YHD9|H0YHD9_HUMAN,tr|F8W1S1|F8W1S1_HUMAN,tr|F8VS61|F8VS61_HUMAN" 26 834.4367 262.83 13730 13399 2 834.432353 418.2256 "Keratin, type II cytoskeletal 73 OS=Homo sapiens OX=9606 GN=KRT73 PE=1 SV=1" 5.84 2765.5 - 3.12E+06 - - - -5.2155 - 1.431 0.111 - 172.1 1 2 0 -0.0044 7 0 0 0 5.14E+10 1.95E+08 - - - 0.995 0.997 221125_WJC_METTL3_EV_vs_WT_F02.13400.13400.2 0.163 18-Jul K.QYGNEVFLAK.L "sp|P50990|TCPQ_HUMAN,tr|H7C4C8|H7C4C8_HUMAN" 2 1167.5924 0.36 13731 13400 2 1167.590606 584.8035 T-complex protein 1 subunit theta OS=Homo sapiens OX=9606 GN=CCT8 PE=1 SV=4 6 2765.6 - 3.04E+06 - - - -1.5571 - 1.307 0.278 - 170.8 1 2 0 -0.0018 10 0 0 0 2.60E+08 7.25E+08 - - - 1.8411 0.9963 221125_WJC_METTL3_EV_vs_WT_F02.13401.13401.2 0.016 12-Jul R.EFEEYIR.D "sp|O14776|TCRG1_HUMAN,tr|A0A7P0T8N8|A0A7P0T8N8_HUMAN,tr|G3V220|G3V220_HUMAN" 3 984.4553 0.59 13732 13401 2 984.455561 493.2349 Transcription elongation regulator 1 OS=Homo sapiens OX=9606 GN=TCERG1 PE=1 SV=2 4.25 2765.7 - 766078 - - - 0.3037 - 1.388 0.173 - 218.8 1 2 0 0.0003 7 0 0 0 2.36E+07 3.98E+07 - - - 1.3575 0.9978 221125_WJC_METTL3_EV_vs_WT_F02.13405.13405.2 0.0127 12-Jul R.EFEEYIR[166.11].D "sp|O14776|TCRG1_HUMAN,tr|A0A7P0T8N8|A0A7P0T8N8_HUMAN,tr|G3V220|G3V220_HUMAN" 3 994.4635 0.59 13734 13405 2 994.462076 498.239 Transcription elongation regulator 1 OS=Homo sapiens OX=9606 GN=TCERG1 PE=1 SV=2 4.25 2766.2 - 1.85E+06 - - - -1.4641 - 1.438 0.253 - 199.5 1 2 0 -0.0015 7 0 0 0 2.36E+07 4.02E+07 - - - 2.0602 0.9998 221125_WJC_METTL3_EV_vs_WT_F02.13408.13408.2 0.000229 18-Nov R.QLGSMVEIAK.Q "sp|Q9HCM9|TRI39_HUMAN,tr|A0A0G2JKY0|A0A0G2JKY0_HUMAN,tr|A0A096LP39|A0A096LP39_HUMAN,tr|A0A140TA46|A0A140TA46_HUMAN,tr|A2AAZ6|A2AAZ6_HUMAN,tr|H0Y735|H0Y735_HUMAN,tr|A2AAZ5|A2AAZ5_HUMAN" 7 1074.5743 0.49 13737 13408 2 1074.574839 538.2944 E3 ubiquitin-protein ligase TRIM39 OS=Homo sapiens OX=9606 GN=TRIM39 PE=1 SV=2 6 2766.6 - 694785 - - - 0.4727 - 1.967 0.431 - 394.2 1 2 0 0.0005 10 0 0 0 3.65E+07 7.48E+07 - - - 4.1126 0.9998 221125_WJC_METTL3_EV_vs_WT_F02.13411.13411.2 0.00313 16-Oct R.VILEIDNAR.L "sp|P19012|K1C15_HUMAN,sp|P13646|K1C13_HUMAN,tr|K7EMD9|K7EMD9_HUMAN,tr|K7ERE3|K7ERE3_HUMAN" 4 1041.5819 1877.8 13738 13411 2 1041.580558 521.7982 "Keratin, type I cytoskeletal 15 OS=Homo sapiens OX=9606 GN=KRT15 PE=1 SV=3" 4.37 2767 - 1.58E+07 - - - -1.2491 - 1.941 0.447 - 431 1 2 0 -0.0013 9 0 0 0 4.98E+08 2.65E+05 - - - 4.2608 0.855 221125_WJC_METTL3_EV_vs_WT_F02.13412.13412.2 0.0107 16-Aug R.EVVLLTDDR.N sp|Q86US8|EST1A_HUMAN 1 1058.5608 1.2 13739 13412 2 1058.55366 530.2877 Telomerase-binding protein EST1A OS=Homo sapiens OX=9606 GN=SMG6 PE=1 SV=2 4.03 2767.1 - 622179 - - - -6.7346 - 1.601 0.159 - 166.6 1 2 0 -0.0071 9 0 0 0 2.39E+07 1.99E+07 - - - 1.5747 0.9954 221125_WJC_METTL3_EV_vs_WT_F02.13413.13413.2 1.34 14-Jun K.EFTNVYIK.N "sp|Q13310|PABP4_HUMAN,sp|P11940|PABP1_HUMAN,sp|P0CB38|PAB4L_HUMAN,tr|A0A7I2V5W9|A0A7I2V5W9_HUMAN,tr|A0A7I2YQE4|A0A7I2YQE4_HUMAN,tr|A0A7I2V649|A0A7I2V649_HUMAN,tr|B1ANR0|B1ANR0_HUMAN,tr|A0A7I2V4L7|A0A7I2V4L7_HUMAN,tr|H0YCC8|H0YCC8_HUMAN,tr|H0YAR2|H0YAR2_HUMAN,tr|E7ERJ7|E7ERJ7_HUMAN,tr|A0A7I2V598|A0A7I2V598_HUMAN,tr|A0A7I2YQ88|A0A7I2YQ88_HUMAN,tr|H0Y5F5|H0Y5F5_HUMAN,tr|H0YBN4|H0YBN4_HUMAN,tr|A0A087WTT1|A0A087WTT1_HUMAN,tr|A0A7I2YQ90|A0A7I2YQ90_HUMAN,tr|A0A7I2V4N4|A0A7I2V4N4_HUMAN,tr|E7EQV3|E7EQV3_HUMAN" 19 1012.5229 1.26 13740 13413 2 1012.522641 507.2687 Polyadenylate-binding protein 4 OS=Homo sapiens OX=9606 GN=PABPC4 PE=1 SV=1 6.1 2767.1 - 2.73E+07 - - - -0.3022 - 1.239 0.2 - 130 1 2 0 -0.0003 8 0 0 0 1.04E+09 8.27E+08 - - - 1.1644 0.9997 221125_WJC_METTL3_EV_vs_WT_F02.13414.13414.2 0.00743 18-Dec K.WEAEPVYVQR.A "sp|P25311|ZA2G_HUMAN,tr|C9JEV0|C9JEV0_HUMAN" 2 1275.6248 105.97 13741 13414 2 1275.62377 638.8197 Zinc-alpha-2-glycoprotein OS=Homo sapiens OX=9606 GN=AZGP1 PE=1 SV=2 4.53 2767.3 - 598965 - - - -0.7973 - 1.94 0.4 - 615.3 1 2 0 -0.001 10 0 0 0 1.52E+07 1.43E+05 - - - 3.8448 0.9972 221125_WJC_METTL3_EV_vs_WT_F02.13415.13415.2 0.124 18-Jun R.LFFAGEHTIR.N "sp|O60341|KDM1A_HUMAN,tr|R4GMQ1|R4GMQ1_HUMAN,tr|R4GMP9|R4GMP9_HUMAN" 3 1189.6244 2 13742 13415 2 1189.623247 595.8195 Lysine-specific histone demethylase 1A OS=Homo sapiens OX=9606 GN=KDM1A PE=1 SV=2 6.75 2767.4 - 513665 - - - -0.9633 - 1.234 0.274 - 83.6 1 2 0 -0.0011 10 0 0 0 6.94E+06 3.47E+06 - - - 1.6513 0.8445 221125_WJC_METTL3_EV_vs_WT_F02.13420.13420.2 0.373 14-Jul L.R[166.11]GLDALSK.K "sp|Q92736|RYR2_HUMAN,tr|H7BY35|H7BY35_HUMAN" 2 868.5006 - 13745 13420 2 868.501093 435.2576 Ryanodine receptor 2 OS=Homo sapiens OX=9606 GN=RYR2 PE=1 SV=3 8.75 2768 - 2.69E+06 - - - 0.5838 - 1.464 0.184 - 223.4 1 1 0 0.0005 8 0 0 0 - - - - - 1.5495 0.9989 221125_WJC_METTL3_EV_vs_WT_F02.13423.13423.2 0.141 14-Aug K.QLIDITGK.N "sp|Q14157|UBP2L_HUMAN,tr|Q5VU78|Q5VU78_HUMAN,tr|F8W726|F8W726_HUMAN,tr|Q5VU81|Q5VU81_HUMAN,tr|Q5VU79|Q5VU79_HUMAN,tr|Q5VU80|Q5VU80_HUMAN,tr|Q5VU77|Q5VU77_HUMAN" 7 886.5124 2.02 13747 13423 2 886.511473 444.2635 Ubiquitin-associated protein 2-like OS=Homo sapiens OX=9606 GN=UBAP2L PE=1 SV=2 5.84 2768.3 - 8.75E+07 - - - -1.0265 - 1.49 0.305 - 290.1 1 2 0 -0.0009 8 0 0 0 1.65E+09 8.16E+08 - - - 2.4961 0.9999 221125_WJC_METTL3_EV_vs_WT_F02.13427.13427.2 0.00017 18-Nov R.QLGSMVEIAK.Q "sp|Q9HCM9|TRI39_HUMAN,tr|A0A0G2JKY0|A0A0G2JKY0_HUMAN,tr|A0A096LP39|A0A096LP39_HUMAN,tr|A0A140TA46|A0A140TA46_HUMAN,tr|A2AAZ6|A2AAZ6_HUMAN,tr|H0Y735|H0Y735_HUMAN,tr|A2AAZ5|A2AAZ5_HUMAN" 7 1074.5743 0.49 13750 13427 2 1074.574168 538.2944 E3 ubiquitin-protein ligase TRIM39 OS=Homo sapiens OX=9606 GN=TRIM39 PE=1 SV=2 6 2768.7 - 1.68E+06 - - - -0.1517 - 2.146 0.459 - 440.4 1 2 0 -0.0002 10 0 0 0 3.65E+07 7.48E+07 - - - 4.5626 0.9848 221125_WJC_METTL3_EV_vs_WT_F02.13428.13428.2 1.9 12-Jul R.GLGQLIR[166.11].A "sp|Q5UIP0|RIF1_HUMAN,tr|H7C2B5|H7C2B5_HUMAN" 2 765.4736 0.001 13751 13428 2 765.473026 383.7441 Telomere-associated protein RIF1 OS=Homo sapiens OX=9606 GN=RIF1 PE=1 SV=2 9.75 2768.8 - 1.36E+06 - - - -0.806 - 1.245 0.091 - 195 1 2 0 -0.0006 7 0 0 0 0.00E+00 3.70E+07 - - - 0.4073 0.8136 221125_WJC_METTL3_EV_vs_WT_F02.13435.13435.2 0.155 12-Jun Q.LFEELGK[136.11].G "sp|Q9UQM7|KCC2A_HUMAN,sp|P34932|HSP74_HUMAN,sp|Q13555|KCC2G_HUMAN,sp|Q13557|KCC2D_HUMAN,tr|A0A5F9ZH21|A0A5F9ZH21_HUMAN,tr|E9PBG7|E9PBG7_HUMAN,tr|A0A2Q3DQE3|A0A2Q3DQE3_HUMAN,tr|A0A804HLD1|A0A804HLD1_HUMAN,tr|A0A5F9ZHY2|A0A5F9ZHY2_HUMAN,tr|H0Y6G2|H0Y6G2_HUMAN,tr|A0A5K1VW76|A0A5K1VW76_HUMAN,tr|A0A5F9ZHR5|A0A5F9ZHR5_HUMAN,tr|D6R938|D6R938_HUMAN,tr|E9PF82|E9PF82_HUMAN,tr|A0A804HIC9|A0A804HIC9_HUMAN,tr|A0A5F9ZH50|A0A5F9ZH50_HUMAN,tr|A0A5F9ZHM9|A0A5F9ZHM9_HUMAN,tr|D6RFJ0|D6RFJ0_HUMAN,tr|Q5SWX3|Q5SWX3_HUMAN" 19 842.4629 0.08 13756 13435 2 842.462046 422.2387 Calcium\calmodulin-dependent protein kinase type II subunit alpha OS=Homo sapiens OX=9606 GN=CAMK2A PE=1 SV=2 4.53 2769.6 - 8.29E+06 - - - -1.0374 - 1.341 0.2 - 110.9 1 1 0 -0.0009 7 0 0 0 6.36E+07 8.31E+08 - - - 1.4476 0.986 221125_WJC_METTL3_EV_vs_WT_F02.13436.13436.2 0.0146 18-Oct K.LVESLPQEIK.A "sp|P52815|RM12_HUMAN,tr|B4DLN1|B4DLN1_HUMAN" 2 1154.6547 2.16 13757 13436 2 1154.658142 578.3346 "39S ribosomal protein L12, mitochondrial OS=Homo sapiens OX=9606 GN=MRPL12 PE=1 SV=2" 4.53 2769.7 - 3.71E+06 - - - 2.9896 - 1.568 0.157 - 282.3 1 2 0 0.0035 10 0 0 0 1.93E+09 8.96E+08 - - - 1.455 0.9982 221125_WJC_METTL3_EV_vs_WT_F02.13437.13437.2 0.132 18-Dec K.LVESLPQEIK[136.11].A "sp|P52815|RM12_HUMAN,tr|B4DLN1|B4DLN1_HUMAN" 2 1162.6689 2.16 13758 13437 2 1162.671569 582.3417 "39S ribosomal protein L12, mitochondrial OS=Homo sapiens OX=9606 GN=MRPL12 PE=1 SV=2" 4.53 2769.7 - 2.46E+06 - - - 2.3042 - 1.622 0.321 - 412.9 1 2 0 0.0027 10 0 0 0 1.93E+09 8.96E+08 - - - 2.7611 0.9987 221125_WJC_METTL3_EV_vs_WT_F02.13439.13439.2 0.0461 14-Jul R.VEEFLYEK[136.11].L "sp|Q9NR46|SHLB2_HUMAN,tr|F8WFB9|F8WFB9_HUMAN,tr|B7ZC39|B7ZC39_HUMAN,tr|H7C1Z6|H7C1Z6_HUMAN,tr|B7ZC38|B7ZC38_HUMAN" 5 1063.5317 1.04 13760 13439 2 1063.531538 532.7731 Endophilin-B2 OS=Homo sapiens OX=9606 GN=SH3GLB2 PE=1 SV=1 4.25 2769.9 - 943333 - - - -0.1787 - 1.443 0.269 - 173.8 1 2 0 -0.0002 8 0 0 0 5.71E+07 5.50E+07 - - - 2.1338 0.959 221125_WJC_METTL3_EV_vs_WT_F02.13440.13440.2 0.03 14-Aug R.LPLQDVYK.L "sp|Q05639|EF1A2_HUMAN,sp|P68104|EF1A1_HUMAN,sp|Q5VTE0|EF1A3_HUMAN,tr|A0A7I2V659|A0A7I2V659_HUMAN,tr|A0A7I2V3H3|A0A7I2V3H3_HUMAN,tr|A0A2U3TZH3|A0A2U3TZH3_HUMAN,tr|A0A7I2V5N4|A0A7I2V5N4_HUMAN,tr|A0A087WVQ9|A0A087WVQ9_HUMAN,tr|A0A087WV01|A0A087WV01_HUMAN" 9 974.5437 0.37 13761 13440 2 974.549931 488.2791 Elongation factor 1-alpha 2 OS=Homo sapiens OX=9606 GN=EEF1A2 PE=1 SV=1 5.83 2769.9 - 839806 - - - 6.4112 - 1.604 0.278 - 241.8 1 2 0 0.0062 8 0 0 0 2.82E+09 7.65E+09 - - - 2.5174 0.9989 221125_WJC_METTL3_EV_vs_WT_F02.13445.13445.2 0.0236 12-Oct K.TDLFYER[166.11].K sp|Q7RTV0|PHF5A_HUMAN 1 952.453 1.08 13764 13445 2 952.451664 477.2338 PHD finger-like domain-containing protein 5A OS=Homo sapiens OX=9606 GN=PHF5A PE=1 SV=1 4.37 2770.6 - 1.54E+06 - - - -1.368 - 1.802 0.231 - 509.8 1 2 0 -0.0013 7 0 0 0 1.95E+08 1.81E+08 - - - 2.6127 0.9993 221125_WJC_METTL3_EV_vs_WT_F02.13446.13446.2 1.45E-06 20-Nov K.VVLLGEGC[160.03]VGK[136.11].T sp|Q9UL25|RAB21_HUMAN 1 1137.6307 1.58 13765 13446 2 1137.634786 569.8226 Ras-related protein Rab-21 OS=Homo sapiens OX=9606 GN=RAB21 PE=1 SV=3 5.97 2770.7 - 1.02E+06 - - - 3.5653 - 2.428 0.503 - 475 1 2 0 0.0041 11 0 0 0 1.71E+09 1.08E+09 - - - 5.1546 0.999 221125_WJC_METTL3_EV_vs_WT_F02.13449.13449.2 0.000598 14-Aug K.QLFAC[160.03]VPK.T "sp|Q8IWZ3|ANKH1_HUMAN,tr|A0A0A0MQZ8|A0A0A0MQZ8_HUMAN,tr|H0Y472|H0Y472_HUMAN,tr|H0Y7Y3|H0Y7Y3_HUMAN,tr|H0Y4P6|H0Y4P6_HUMAN,tr|H0Y785|H0Y785_HUMAN" 6 961.5055 1.16 13768 13449 2 961.504331 481.76 Ankyrin repeat and KH domain-containing protein 1 OS=Homo sapiens OX=9606 GN=ANKHD1 PE=1 SV=1 8.22 2771.1 - 732929 - - - -1.2397 - 1.567 0.299 - 252.2 1 2 0 -0.0012 8 0 0 0 1.27E+08 1.09E+08 - - - 2.6037 0.9975 221125_WJC_METTL3_EV_vs_WT_F02.13450.13450.2 0.0182 14-Aug K.QLFAC[160.03]VPK[136.11].T "sp|Q8IWZ3|ANKH1_HUMAN,tr|A0A0A0MQZ8|A0A0A0MQZ8_HUMAN,tr|H0Y472|H0Y472_HUMAN,tr|H0Y7Y3|H0Y7Y3_HUMAN,tr|H0Y4P6|H0Y4P6_HUMAN,tr|H0Y785|H0Y785_HUMAN" 6 969.5197 1.54 13769 13450 2 969.51631 485.7671 Ankyrin repeat and KH domain-containing protein 1 OS=Homo sapiens OX=9606 GN=ANKHD1 PE=1 SV=1 8.22 2771.2 - 732252 - - - -3.5203 - 1.558 0.396 - 268 1 2 0 -0.0034 8 0 0 0 1.72E+08 1.12E+08 - - - 3.3021 0.9998 221125_WJC_METTL3_EV_vs_WT_F02.13451.13451.2 0.00032 20-Oct K.LTPEEEEILNK.K "sp|P62241|RS8_HUMAN,tr|Q5JR95|Q5JR95_HUMAN" 2 1313.6715 1.1 13770 13451 2 1313.671994 657.843 40S ribosomal protein S8 OS=Homo sapiens OX=9606 GN=RPS8 PE=1 SV=2 4.09 2771.4 - 519069 - - - 0.405 - 1.887 0.425 - 240.7 1 2 0 0.0005 11 0 0 0 2.66E+08 2.41E+08 - - - 3.8977 1 221125_WJC_METTL3_EV_vs_WT_F02.13452.13452.3 1.02E-07 17/72 R.GLLQDDAHPTLVTYADHSK[136.11].L "sp|Q86U44|MTA70_HUMAN,tr|F5H6D8|F5H6D8_HUMAN,tr|H0YFV6|H0YFV6_HUMAN,tr|B4DTN4|B4DTN4_HUMAN" 4 2088.0367 0.01 13771 13452 3 2088.033889 697.0195 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 5.13 2771.5 - 472247 - - - -1.362 - 3.231 0.589 - 333 1 2 0 -0.0028 19 0 0 0 3.04E+06 2.52E+08 - - - 7.9873 0.9996 221125_WJC_METTL3_EV_vs_WT_F02.13456.13456.2 0.119 16-Oct R.LMEEIMSEK.E "sp|P17844|DDX5_HUMAN,tr|A0A7I2V5F5|A0A7I2V5F5_HUMAN,tr|J3QSF1|J3QSF1_HUMAN,tr|A0A7I2V507|A0A7I2V507_HUMAN,tr|J3KTA4|J3KTA4_HUMAN,tr|A0A0G2JLI4|A0A0G2JLI4_HUMAN,tr|A0A7I2V2S0|A0A7I2V2S0_HUMAN" 7 1108.5144 1.3 13773 13456 2 1108.512998 555.2645 Probable ATP-dependent RNA helicase DDX5 OS=Homo sapiens OX=9606 GN=DDX5 PE=1 SV=1 4.25 2772 - 4.15E+06 - - - -1.2945 - 1.891 0.377 - 334.6 1 2 0 -0.0014 9 0 0 0 6.32E+08 4.87E+08 - - - 3.6683 0.9994 221125_WJC_METTL3_EV_vs_WT_F02.13457.13457.2 0.0223 14-Aug R.VEEFLYEK.L "sp|Q9NR46|SHLB2_HUMAN,tr|F8WFB9|F8WFB9_HUMAN,tr|B7ZC39|B7ZC39_HUMAN,tr|H7C1Z6|H7C1Z6_HUMAN,tr|B7ZC38|B7ZC38_HUMAN" 5 1055.5175 1.01 13774 13457 2 1055.516842 528.766 Endophilin-B2 OS=Homo sapiens OX=9606 GN=SH3GLB2 PE=1 SV=1 4.25 2772.1 - 2.67E+06 - - - -0.6499 - 1.729 0.298 - 214.7 1 2 0 -0.0007 8 0 0 0 5.71E+07 5.63E+07 - - - 2.8932 0.9956 221125_WJC_METTL3_EV_vs_WT_F02.13458.13458.2 0.000142 20-Nov K.VVLLGEGC[160.03]VGK.T sp|Q9UL25|RAB21_HUMAN 1 1129.6165 1.58 13775 13458 2 1129.620173 565.8155 Ras-related protein Rab-21 OS=Homo sapiens OX=9606 GN=RAB21 PE=1 SV=3 5.97 2772.1 - 2.49E+06 - - - 3.225 - 2.095 0.203 - 430.2 1 2 0 0.0036 11 0 0 0 1.71E+09 1.08E+09 - - - 2.5399 0.9997 221125_WJC_METTL3_EV_vs_WT_F02.13459.13459.2 0.000308 20-Oct K.LTPEEEEILNK[136.11].K "sp|P62241|RS8_HUMAN,tr|Q5JR95|Q5JR95_HUMAN" 2 1321.6857 1.1 13776 13459 2 1321.683786 661.8501 40S ribosomal protein S8 OS=Homo sapiens OX=9606 GN=RPS8 PE=1 SV=2 4.09 2772.3 - 977823 - - - -1.4194 - 1.886 0.423 - 193.9 1 2 0 -0.0019 11 0 0 0 2.66E+08 2.41E+08 - - - 3.881 0.9938 221125_WJC_METTL3_EV_vs_WT_F02.13462.13462.2 0.627 14-Jul R.ALTLGLAK.R sp|Q9BUH6|PAXX_HUMAN 1 785.5011 1.24 13779 13462 2 785.500456 393.7578 Protein PAXX OS=Homo sapiens OX=9606 GN=PAXX PE=1 SV=2 8.8 2772.7 - 373337 - - - -0.8071 - 1.224 0.186 - 135.7 1 2 0 -0.0006 8 0 0 0 2.31E+07 1.86E+07 - - - 1.0242 0.9996 221125_WJC_METTL3_EV_vs_WT_F02.13463.13463.2 0.000402 20-Aug R.LLTPTHSFLAR[166.11].S "sp|Q14244|MAP7_HUMAN,tr|A0A087WZ40|A0A087WZ40_HUMAN" 2 1264.7167 0.94 13780 13463 2 1264.714698 633.3656 Ensconsin OS=Homo sapiens OX=9606 GN=MAP7 PE=1 SV=1 9.76 2772.8 - 234759 - - - -1.6043 - 1.642 0.451 - 247.2 1 2 0 -0.002 11 0 0 0 4.84E+06 5.15E+06 - - - 3.713 0.9998 221125_WJC_METTL3_EV_vs_WT_F02.13466.13466.2 0.00124 16-Sep K.EGLPVALDK[136.11].H sp|Q9Y224|RTRAF_HUMAN 1 948.5371 1.35 13781 13466 2 948.536478 475.2758 "RNA transcription, translation and transport factor protein OS=Homo sapiens OX=9606 GN=RTRAF PE=1 SV=1" 4.37 2773.2 - 5.53E+06 - - - -0.7053 - 1.87 0.481 - 282.8 1 2 0 -0.0007 9 0 0 0 4.91E+08 3.64E+08 - - - 4.4043 0.9976 221125_WJC_METTL3_EV_vs_WT_F02.13467.13467.2 0.012 16-Sep R.LMEEIMSEK[136.11].E "sp|P17844|DDX5_HUMAN,tr|A0A7I2V5F5|A0A7I2V5F5_HUMAN,tr|J3QSF1|J3QSF1_HUMAN,tr|A0A7I2V507|A0A7I2V507_HUMAN,tr|J3KTA4|J3KTA4_HUMAN,tr|A0A0G2JLI4|A0A0G2JLI4_HUMAN,tr|A0A7I2V2S0|A0A7I2V2S0_HUMAN" 7 1116.5286 1.3 13782 13467 2 1116.524037 559.2716 Probable ATP-dependent RNA helicase DDX5 OS=Homo sapiens OX=9606 GN=DDX5 PE=1 SV=1 4.25 2773.2 - 5.61E+06 - - - -4.1163 - 1.822 0.415 - 231.7 1 2 0 -0.0046 9 0 0 0 6.33E+08 4.88E+08 - - - 3.8404 0.9996 221125_WJC_METTL3_EV_vs_WT_F02.13468.13468.2 0.0269 16-Aug R.LAEPSQLLK.S "sp|P14923|PLAK_HUMAN,tr|C9JKY1|C9JKY1_HUMAN,tr|C9JK18|C9JK18_HUMAN,tr|C9JTX4|C9JTX4_HUMAN,tr|C9J826|C9J826_HUMAN" 5 997.5808 20.24 13783 13468 2 997.580246 499.7977 Junction plakoglobin OS=Homo sapiens OX=9606 GN=JUP PE=1 SV=3 6 2773.3 - 1.27E+07 - - - -0.5523 - 1.758 0.367 - 186.9 1 2 0 -0.0006 9 0 0 0 5.45E+08 2.69E+07 - - - 3.3837 0.9997 221125_WJC_METTL3_EV_vs_WT_F02.13469.13469.2 7.35E-05 16-Aug K.GDVGLGLVK[136.11].E sp|Q7KZF4|SND1_HUMAN 1 864.516 0.95 13784 13469 2 864.515541 433.2653 Staphylococcal nuclease domain-containing protein 1 OS=Homo sapiens OX=9606 GN=SND1 PE=1 SV=1 5.84 2773.4 - 1.59E+06 - - - -0.5518 - 1.816 0.398 - 188.5 1 2 0 -0.0005 9 0 0 0 2.56E+07 2.68E+07 - - - 3.7066 0.9979 221125_WJC_METTL3_EV_vs_WT_F02.13470.13470.2 0.078 14-Jun R.GLVLVPSR[166.11].E sp|Q9NUL7|DDX28_HUMAN 1 849.5312 0.68 13785 13470 2 849.529897 425.7729 Probable ATP-dependent RNA helicase DDX28 OS=Homo sapiens OX=9606 GN=DDX28 PE=1 SV=2 9.75 2773.4 - 1.43E+06 - - - -1.4843 - 1.554 0.235 - 124.6 1 2 0 -0.0013 8 0 0 0 5.14E+07 7.61E+07 - - - 2.1058 0.9959 221125_WJC_METTL3_EV_vs_WT_F02.13473.13473.2 0.00075 16-Jul K.VEEEIVTLR[166.11].Q "sp|O43399|TPD54_HUMAN,tr|A0A087WZ51|A0A087WZ51_HUMAN,tr|A0A087WYR3|A0A087WYR3_HUMAN" 3 1096.6004 1 13787 13473 2 1096.597681 549.3075 Tumor protein D54 OS=Homo sapiens OX=9606 GN=TPD52L2 PE=1 SV=2 4.25 2773.8 - 3.51E+06 - - - -2.443 - 1.816 0.197 - 250.7 2 2 0 -0.0027 9 0 0 0 1.61E+08 1.61E+08 - - - 2.0868 1 221125_WJC_METTL3_EV_vs_WT_F02.13476.13476.4 2.67E-05 11/108 R.GLLQDDAHPTLVTYADHSK[136.11].L "sp|Q86U44|MTA70_HUMAN,tr|F5H6D8|F5H6D8_HUMAN,tr|H0YFV6|H0YFV6_HUMAN,tr|B4DTN4|B4DTN4_HUMAN" 4 2088.0367 0.02 13789 13476 4 2088.033742 523.0165 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 5.13 2774 - 1.40E+07 - - - -1.4324 - 2.538 0.528 - 112.4 1 2 0 -0.003 19 0 0 0 1.47E+07 6.41E+08 - - - 4.1359 0.999 221125_WJC_METTL3_EV_vs_WT_F02.13480.13480.2 0.986 16-Sep R.IDISPSTLR.K "sp|Q9NYF8|BCLF1_HUMAN,tr|E9PKI6|E9PKI6_HUMAN,tr|A0A1W2PQ43|A0A1W2PQ43_HUMAN,tr|E9PK91|E9PK91_HUMAN,tr|E9PK09|E9PK09_HUMAN,tr|E9PQN2|E9PQN2_HUMAN" 6 1000.5553 2.06 13792 13480 2 1000.554587 501.2849 Bcl-2-associated transcription factor 1 OS=Homo sapiens OX=9606 GN=BCLAF1 PE=1 SV=2 5.84 2774.4 - 4.25E+07 - - - -0.7226 - 1.969 0.201 - 227.3 1 2 0 -0.0007 9 0 0 0 2.47E+09 1.20E+09 - - - 2.4855 1 221125_WJC_METTL3_EV_vs_WT_F02.13492.13492.2 1.90E-07 18-Dec R.YGVIIVGNPK[136.11].A sp|Q92900|RENT1_HUMAN 1 1066.6266 1 13801 13492 2 1066.625688 534.3206 Regulator of nonsense transcripts 1 OS=Homo sapiens OX=9606 GN=UPF1 PE=1 SV=2 8.59 2776 - 2.07E+06 - - - -0.8841 - 2.471 0.581 - 734.6 1 2 0 -0.0009 10 0 0 0 8.82E+07 8.86E+07 - - - 5.857 0.9999 221125_WJC_METTL3_EV_vs_WT_F02.13493.13493.2 0.00109 13/18 K.LAEAQIEELR[166.11].Q "sp|Q9NR28|DBLOH_HUMAN,tr|A0A024RBT2|A0A024RBT2_HUMAN" 2 1180.6327 1.27 13802 13493 2 1180.633267 591.3236 "Diablo homolog, mitochondrial OS=Homo sapiens OX=9606 GN=DIABLO PE=1 SV=1" 4.25 2776.1 - 1.18E+06 - - - 0.4616 - 2.865 0.444 - 826.1 1 2 0 0.0005 10 0 0 0 4.39E+07 3.45E+07 - - - 5.2583 0.9895 221125_WJC_METTL3_EV_vs_WT_F02.13495.13495.2 3.66 12-Aug R.TLQVLIK[136.11].Q "sp|Q7Z3B4|NUP54_HUMAN,sp|P35219|CAH8_HUMAN" 2 821.5466 1.71 13804 13495 2 821.545247 411.7806 Nucleoporin p54 OS=Homo sapiens OX=9606 GN=NUP54 PE=1 SV=2 8.41 2776.2 - 1.28E+06 - - - -1.6347 - 1.359 0.126 - 247.7 1 2 0 -0.0013 7 0 0 0 2.58E+08 1.51E+08 - - - 0.9432 0.9718 221125_WJC_METTL3_EV_vs_WT_F02.13497.13497.2 0.121 16-Jul R.C[160.03]LQSGTLFR.D "sp|P07384|CAN1_HUMAN,tr|E9PJA6|E9PJA6_HUMAN,tr|E9PIA9|E9PIA9_HUMAN,tr|E9PLX0|E9PLX0_HUMAN,tr|E9PQB3|E9PQB3_HUMAN,tr|E9PMC6|E9PMC6_HUMAN,tr|E9PSA6|E9PSA6_HUMAN,tr|E9PLC9|E9PLC9_HUMAN,tr|E9PJJ3|E9PJJ3_HUMAN,tr|E9PRM1|E9PRM1_HUMAN" 10 1080.5386 13.94 13806 13497 2 1080.533948 541.2766 Calpain-1 catalytic subunit OS=Homo sapiens OX=9606 GN=CAPN1 PE=1 SV=1 8.25 2776.5 - 558560 - - - -4.3182 - 1.309 0.245 - 121.3 1 2 0 -0.0047 9 0 0 0 1.38E+07 9.88E+05 - - - 1.6281 0.9989 221125_WJC_METTL3_EV_vs_WT_F02.13501.13501.2 0.0452 12-Jun K.AWEDYYK.K sp|Q96I24|FUBP3_HUMAN 1 973.4181 1.64 13808 13501 2 973.417627 487.7164 Far upstream element-binding protein 3 OS=Homo sapiens OX=9606 GN=FUBP3 PE=1 SV=2 4.37 2776.9 - 7.99E+06 - - - -0.5352 - 1.112 0.401 - 149.9 1 2 0 -0.0005 7 0 0 0 6.76E+08 4.12E+08 - - - 2.339 0.9998 221125_WJC_METTL3_EV_vs_WT_F02.13502.13502.2 8.89E-07 18-Oct R.YGVIIVGNPK.A sp|Q92900|RENT1_HUMAN 1 1058.6124 1 13809 13502 2 1058.611299 530.3135 Regulator of nonsense transcripts 1 OS=Homo sapiens OX=9606 GN=UPF1 PE=1 SV=2 8.59 2776.9 - 2.13E+06 - - - -1.0693 - 2.169 0.411 - 532.1 1 2 0 -0.0011 10 0 0 0 8.82E+07 8.86E+07 - - - 4.2375 1 221125_WJC_METTL3_EV_vs_WT_F02.13504.13504.3 5.78E-14 17/96 K.LVQDVANNTNEEAGDGTTTATVLAR.S "sp|P10809|CH60_HUMAN,tr|C9JL25|C9JL25_HUMAN,tr|A0A7I2V2X6|A0A7I2V2X6_HUMAN,tr|A0A7I2YQK6|A0A7I2YQK6_HUMAN,tr|A0A7I2V599|A0A7I2V599_HUMAN,tr|E7EXB4|E7EXB4_HUMAN,tr|A0A7I2YQ71|A0A7I2YQ71_HUMAN,tr|E7ESH4|E7ESH4_HUMAN,tr|A0A7I2V5M1|A0A7I2V5M1_HUMAN,tr|A0A7I2V5K3|A0A7I2V5K3_HUMAN,tr|A0A7I2V369|A0A7I2V369_HUMAN" 11 2559.2413 1.43 13811 13504 3 2559.242728 854.0877 "60 kDa heat shock protein, mitochondrial OS=Homo sapiens OX=9606 GN=HSPD1 PE=1 SV=2" 3.92 2777.2 - 495349 - - - 0.5763 - 3.575 0.708 - 344.9 1 2 0 0.0015 25 0 0 0 1.46E+07 1.02E+07 - - - 9.364 0.9965 221125_WJC_METTL3_EV_vs_WT_F02.13508.13508.2 0.0314 12-Jul K.SLDFYTR[166.11].V sp|Q04760|LGUL_HUMAN 1 910.4424 0.88 13813 13508 2 910.441835 456.2285 Lactoylglutathione lyase OS=Homo sapiens OX=9606 GN=GLO1 PE=1 SV=4 5.55 2777.7 - 2.24E+06 - - - -0.6228 - 1.084 0.285 - 182.2 1 2 0 -0.0006 7 0 0 0 4.77E+07 5.41E+07 - - - 1.4014 0.9732 221125_WJC_METTL3_EV_vs_WT_F02.13516.13516.2 0.33 14-Jul K.AGLYGLPR[166.11].R "sp|P49327|FAS_HUMAN,tr|A0A0U1RQF0|A0A0U1RQF0_HUMAN,tr|A0A0U1RRG3|A0A0U1RRG3_HUMAN" 3 855.4842 1.06 13817 13516 2 855.486068 428.7494 Fatty acid synthase OS=Homo sapiens OX=9606 GN=FASN PE=1 SV=3 8.79 2778.6 - 1.20E+06 - - - 2.1742 - 1.32 0.096 - 124.2 1 2 0 0.0019 8 0 0 0 7.80E+07 7.34E+07 - - - 0.5868 1 221125_WJC_METTL3_EV_vs_WT_F02.13517.13517.3 1.62E-13 19/96 K.LVQDVANNTNEEAGDGTTTATVLAR[166.11].S "sp|P10809|CH60_HUMAN,tr|C9JL25|C9JL25_HUMAN,tr|A0A7I2V2X6|A0A7I2V2X6_HUMAN,tr|A0A7I2YQK6|A0A7I2YQK6_HUMAN,tr|A0A7I2V599|A0A7I2V599_HUMAN,tr|E7EXB4|E7EXB4_HUMAN,tr|A0A7I2YQ71|A0A7I2YQ71_HUMAN,tr|E7ESH4|E7ESH4_HUMAN,tr|A0A7I2V5M1|A0A7I2V5M1_HUMAN,tr|A0A7I2V5K3|A0A7I2V5K3_HUMAN,tr|A0A7I2V369|A0A7I2V369_HUMAN" 11 2569.2495 1.43 13818 13517 3 2569.244908 857.4238 "60 kDa heat shock protein, mitochondrial OS=Homo sapiens OX=9606 GN=HSPD1 PE=1 SV=2" 3.92 2778.8 - 654190 - - - -1.7962 - 3.689 0.7 - 333.9 1 2 0 -0.0046 25 0 0 0 1.46E+07 1.02E+07 - - - 9.3462 0.9997 221125_WJC_METTL3_EV_vs_WT_F02.13518.13518.2 0.0289 18-Oct K.LNVEEGLYSR[166.11].T sp|Q68CQ7|GL8D1_HUMAN 1 1188.6014 0.79 13819 13518 2 1188.599711 595.308 Glycosyltransferase 8 domain-containing protein 1 OS=Homo sapiens OX=9606 GN=GLT8D1 PE=1 SV=2 4.53 2778.9 - 616508 - - - -1.4395 - 2.249 0.357 - 363.7 1 2 0 -0.0017 10 0 0 0 1.76E+07 2.24E+07 - - - 3.9396 0.889 221125_WJC_METTL3_EV_vs_WT_F02.13527.13527.2 1.85 12-May K.NVEGLK[136.11]L.- sp|Q96GA3|LTV1_HUMAN 1 779.4633 1.1 13825 13527 2 779.462177 390.7389 Protein LTV1 homolog OS=Homo sapiens OX=9606 GN=LTV1 PE=1 SV=1 6 2779.9 - 878270 - - - -1.3817 - 0.917 0.085 - 82.7 2 2 0 -0.0011 7 0 0 0 3.79E+07 3.43E+07 - - - -0.7405 0.9964 221125_WJC_METTL3_EV_vs_WT_F02.13530.13530.2 0.000229 16-Aug K.NLVTEDVMR.M "sp|P06744|G6PI_HUMAN,tr|A0A2R8Y6C7|A0A2R8Y6C7_HUMAN,tr|K7ERK8|K7ERK8_HUMAN,tr|K7EP41|K7EP41_HUMAN,tr|K7ELR7|K7ELR7_HUMAN,tr|A0A0J9YYI8|A0A0J9YYI8_HUMAN,tr|K7ENA0|K7ENA0_HUMAN,tr|A0A2R8YF08|A0A2R8YF08_HUMAN,tr|K7EIL4|K7EIL4_HUMAN,tr|A0A0J9YYH3|A0A0J9YYH3_HUMAN,tr|K7EQ48|K7EQ48_HUMAN,tr|A0A2U3TZU2|A0A2U3TZU2_HUMAN,tr|A0A0J9YXM3|A0A0J9YXM3_HUMAN,tr|K7ERC6|K7ERC6_HUMAN,tr|A0A0J9YXH9|A0A0J9YXH9_HUMAN,tr|A0A0J9YXP8|A0A0J9YXP8_HUMAN,tr|A0A0J9YX90|A0A0J9YX90_HUMAN,tr|K7EPY4|K7EPY4_HUMAN" 18 1075.5332 3.24 13826 13530 2 1075.528077 538.7739 Glucose-6-phosphate isomerase OS=Homo sapiens OX=9606 GN=GPI PE=1 SV=4 4.37 2780.4 - 1.29E+06 - - - -4.7576 - 1.753 0.442 - 239 1 2 0 -0.0051 9 0 0 0 1.00E+08 3.09E+07 - - - 3.928 0.8456 221125_WJC_METTL3_EV_vs_WT_F02.13532.13532.2 0.153 16-Jul H.TILLVQPTK.R "sp|P84090|ERH_HUMAN,tr|G3V279|G3V279_HUMAN" 2 1011.6328 2.27 13828 13532 2 1011.631839 506.8237 Enhancer of rudimentary homolog OS=Homo sapiens OX=9606 GN=ERH PE=1 SV=1 8.41 2780.5 - 1.59E+06 - - - -0.9816 - 1.31 0.241 - 122.6 1 1 0 -0.001 9 0 0 0 3.20E+08 1.41E+08 - - - 1.6019 0.894 221125_WJC_METTL3_EV_vs_WT_F02.13533.13533.2 0.0275 12-Jul R.ENILVMR.L "sp|Q15007|FL2D_HUMAN,tr|A0A087X1R4|A0A087X1R4_HUMAN" 2 873.4742 0.82 13829 13533 2 873.47062 437.7444 Pre-mRNA-splicing regulator WTAP OS=Homo sapiens OX=9606 GN=WTAP PE=1 SV=2 6.1 2780.6 - 1.09E+06 - - - -4.1249 - 1.397 0.058 - 202.1 1 2 0 -0.0036 7 0 0 0 4.06E+07 4.97E+07 - - - 0.5276 0.9986 221125_WJC_METTL3_EV_vs_WT_F02.13534.13534.2 2.09 14-Sep R.QLASVILK[136.11].Q sp|Q96P70|IPO9_HUMAN 1 878.5681 0.53 13830 13534 2 878.567615 440.2913 Importin-9 OS=Homo sapiens OX=9606 GN=IPO9 PE=1 SV=3 8.75 2780.7 - 760964 - - - -0.4997 - 1.655 0.205 - 240 1 2 0 -0.0004 8 0 0 0 7.99E+06 1.52E+07 - - - 2.0744 0.9819 221125_WJC_METTL3_EV_vs_WT_F02.13537.13537.2 0.00894 12-Jul R.EHALLAY.T "sp|Q05639|EF1A2_HUMAN,sp|P68104|EF1A1_HUMAN,sp|Q5VTE0|EF1A3_HUMAN,tr|A0A2R8Y488|A0A2R8Y488_HUMAN,tr|A0A7I2V659|A0A7I2V659_HUMAN,tr|A0A7I2V3H3|A0A7I2V3H3_HUMAN,tr|Q5JR01|Q5JR01_HUMAN,tr|A0A2U3TZH3|A0A2U3TZH3_HUMAN,tr|A0A7I2V5N4|A0A7I2V5N4_HUMAN,tr|A0A087WVQ9|A0A087WVQ9_HUMAN,tr|A0A087WV01|A0A087WV01_HUMAN,tr|A0A2R8Y660|A0A2R8Y660_HUMAN" 12 815.4178 - 13831 13537 2 815.416917 408.7162 Elongation factor 1-alpha 2 OS=Homo sapiens OX=9606 GN=EEF1A2 PE=1 SV=1 5.24 2781.1 - 1.47E+07 - - - -1.0265 - 1.49 0.47 - 266.6 1 1 0 -0.0008 7 0 0 0 - - - - - 3.7757 0.9988 221125_WJC_METTL3_EV_vs_WT_F02.13538.13538.2 0.00872 14-Jun R.QYYTLLNK[136.11].A "sp|Q9UN86|G3BP2_HUMAN,tr|A0A7I2V3E2|A0A7I2V3E2_HUMAN,tr|A0A7I2V2R0|A0A7I2V2R0_HUMAN,tr|D6RAC7|D6RAC7_HUMAN,tr|D6RGJ4|D6RGJ4_HUMAN,tr|D6RB17|D6RB17_HUMAN,tr|A0A7I2YQS2|A0A7I2YQS2_HUMAN,tr|A0A7I2YQD9|A0A7I2YQD9_HUMAN,tr|D6R9A4|D6R9A4_HUMAN,tr|D6RBR0|D6RBR0_HUMAN,tr|D6RBW8|D6RBW8_HUMAN" 11 1049.5637 1.35 13832 13538 2 1049.563447 525.7891 Ras GTPase-activating protein-binding protein 2 OS=Homo sapiens OX=9606 GN=G3BP2 PE=1 SV=2 8.5 2781.1 - 9.36E+06 - - - -0.2372 - 1.336 0.314 - 143.1 1 2 0 -0.0002 8 0 0 0 8.28E+08 6.13E+08 - - - 2.2338 0.9997 221125_WJC_METTL3_EV_vs_WT_F02.13539.13539.2 0.0221 14-Aug K.LDVPEDLR.Q "sp|Q06787|FMR1_HUMAN,tr|A0A087WY29|A0A087WY29_HUMAN,tr|R9WNI0|R9WNI0_HUMAN,tr|A8MQB8|A8MQB8_HUMAN,tr|A0A087WXI3|A0A087WXI3_HUMAN,tr|Q8IXW7|Q8IXW7_HUMAN,tr|G3V0J0|G3V0J0_HUMAN" 7 955.4975 2.01 13833 13539 2 955.497034 478.756 Synaptic functional regulator FMR1 OS=Homo sapiens OX=9606 GN=FMR1 PE=1 SV=1 4.03 2781.2 - 2.11E+06 - - - -0.4469 - 1.813 0.381 - 264.7 1 2 0 -0.0004 8 0 0 0 1.84E+08 9.12E+07 - - - 3.6494 0.9998 221125_WJC_METTL3_EV_vs_WT_F02.13540.13540.2 0.00177 20-Oct R.AVLGDDPQLMK.V sp|Q9Y6J9|TAF6L_HUMAN 1 1185.6064 1.21 13834 13540 2 1185.606188 593.8105 TAF6-like RNA polymerase II p300\CBP-associated factor-associated factor 65 kDa subunit 6L OS=Homo sapiens OX=9606 GN=TAF6L PE=1 SV=1 4.21 2781.3 - 1.27E+06 - - - -0.1442 - 1.845 0.42 - 301.3 1 2 0 -0.0002 11 0 0 0 4.65E+07 3.84E+07 - - - 3.8 0.9995 221125_WJC_METTL3_EV_vs_WT_F02.13542.13542.2 0.0003 20-Nov K.ALYETELADAR.R "sp|P20700|LMNB1_HUMAN,tr|A0A0D9SFY5|A0A0D9SFY5_HUMAN,tr|E9PBF6|E9PBF6_HUMAN,tr|A0A0D9SFE5|A0A0D9SFE5_HUMAN" 4 1250.6143 1.23 13836 13542 2 1250.617075 626.3144 Lamin-B1 OS=Homo sapiens OX=9606 GN=LMNB1 PE=1 SV=2 4.14 2781.6 - 675765 - - - 2.2333 - 2.094 0.416 - 420.9 1 2 0 0.0028 11 0 0 0 2.85E+08 2.31E+08 - - - 4.1121 0.9994 221125_WJC_METTL3_EV_vs_WT_F02.13548.13548.2 0.022 18-Sep R.TIAQDYGVLK[136.11].A "sp|Q06830|PRDX1_HUMAN,tr|A0A0A0MSI0|A0A0A0MSI0_HUMAN" 2 1114.6114 0.73 13840 13548 2 1114.611142 558.313 Peroxiredoxin-1 OS=Homo sapiens OX=9606 GN=PRDX1 PE=1 SV=1 5.5 2782.3 - 2.91E+07 - - - -0.209 - 1.659 0.326 - 155 1 2 0 -0.0002 10 0 0 0 1.33E+09 1.83E+09 - - - 2.8618 0.9996 221125_WJC_METTL3_EV_vs_WT_F02.13549.13549.2 1.39E-05 18-Oct R.TIAQDYGVLK.A "sp|Q06830|PRDX1_HUMAN,tr|A0A0A0MSI0|A0A0A0MSI0_HUMAN" 2 1106.5972 0.73 13841 13549 2 1106.597177 554.3059 Peroxiredoxin-1 OS=Homo sapiens OX=9606 GN=PRDX1 PE=1 SV=1 5.5 2782.3 - 1.66E+07 - - - 0.0018 - 1.734 0.377 - 210.6 1 2 0 0 10 0 0 0 1.33E+09 1.83E+09 - - - 3.3619 0.9999 221125_WJC_METTL3_EV_vs_WT_F02.13550.13550.2 9.43E-05 18-Oct K.ITLDNAYMEK.C "sp|P14618|KPYM_HUMAN,tr|H3BQ34|H3BQ34_HUMAN,tr|H3BTJ2|H3BTJ2_HUMAN,tr|B4DNK4|B4DNK4_HUMAN,tr|A0A804F6T5|A0A804F6T5_HUMAN,tr|H3BT25|H3BT25_HUMAN,tr|H3BUW1|H3BUW1_HUMAN,tr|H3BTN5|H3BTN5_HUMAN,tr|A0A804F729|A0A804F729_HUMAN" 9 1196.5747 1.1 13842 13550 2 1196.573831 599.2946 Pyruvate kinase PKM OS=Homo sapiens OX=9606 GN=PKM PE=1 SV=4 4.37 2782.3 - 4.12E+06 - - - -0.7471 - 1.929 0.544 - 270.9 1 2 0 -0.0009 10 0 0 0 6.74E+07 6.11E+07 - - - 4.8926 0.9963 221125_WJC_METTL3_EV_vs_WT_F02.13551.13551.2 0.0649 14-Jul K.INLIAPPR[166.11].Y "sp|P05198|IF2A_HUMAN,tr|H0YJS4|H0YJS4_HUMAN,tr|G3V4T5|G3V4T5_HUMAN" 3 902.5577 1.75 13843 13551 2 902.555998 452.2861 Eukaryotic translation initiation factor 2 subunit 1 OS=Homo sapiens OX=9606 GN=EIF2S1 PE=1 SV=3 9.75 2782.4 - 3.31E+06 - - - -1.8935 - 1.479 0.221 - 150 1 2 0 -0.0017 8 0 0 0 4.97E+08 2.84E+08 - - - 1.8531 0.9997 221125_WJC_METTL3_EV_vs_WT_F02.13552.13552.2 0.00184 14-Oct K.IADFGLC[160.03]K.E "sp|Q16512|PKN1_HUMAN,sp|Q16513|PKN2_HUMAN,sp|Q6P5Z2|PKN3_HUMAN,tr|K7EL10|K7EL10_HUMAN,tr|H0Y429|H0Y429_HUMAN" 5 922.4582 4.69 13844 13552 2 922.456907 462.2364 Serine\threonine-protein kinase N1 OS=Homo sapiens OX=9606 GN=PKN1 PE=1 SV=2 5.83 2782.4 - 2.17E+06 - - - -1.444 - 1.881 0.404 - 234.5 1 2 0 -0.0013 8 0 0 0 4.91E+07 1.05E+07 - - - 3.93 0.9985 221125_WJC_METTL3_EV_vs_WT_F02.13553.13553.2 0.102 16-Sep K.AGLAPLEVR[166.11].V "sp|O75369|FLNB_HUMAN,tr|E7EN95|E7EN95_HUMAN,tr|A0A804HK76|A0A804HK76_HUMAN,tr|A0A804HL72|A0A804HL72_HUMAN" 4 934.5475 1.74 13845 13553 2 934.547497 468.281 Filamin-B OS=Homo sapiens OX=9606 GN=FLNB PE=1 SV=2 6.05 2782.5 - 1.33E+06 - - - -0.0417 - 1.619 0.211 - 202.8 1 2 0 0 9 0 0 0 6.53E+07 3.75E+07 - - - 1.9933 0.9998 221125_WJC_METTL3_EV_vs_WT_F02.13558.13558.2 0.00205 14/20 K.ALYETELADAR[166.11].R "sp|P20700|LMNB1_HUMAN,tr|A0A0D9SFY5|A0A0D9SFY5_HUMAN,tr|E9PBF6|E9PBF6_HUMAN,tr|A0A0D9SFE5|A0A0D9SFE5_HUMAN" 4 1260.6226 1.23 13848 13558 2 1260.62097 631.3186 Lamin-B1 OS=Homo sapiens OX=9606 GN=LMNB1 PE=1 SV=2 4.14 2783.2 - 2.93E+06 - - - -1.2549 - 2.268 0.423 - 723.1 1 2 0 -0.0016 11 0 0 0 2.85E+08 2.31E+08 - - - 4.3801 0.9999 221125_WJC_METTL3_EV_vs_WT_F02.13559.13559.2 0.000672 20-Dec R.LEAQEQAFLAR.L "sp|Q5T3I0|GPTC4_HUMAN,tr|F8W895|F8W895_HUMAN,tr|A0A0A0MRK1|A0A0A0MRK1_HUMAN,tr|E9PAV9|E9PAV9_HUMAN" 4 1274.6619 1.5 13849 13559 2 1274.661558 638.3382 G patch domain-containing protein 4 OS=Homo sapiens OX=9606 GN=GPATCH4 PE=1 SV=2 4.53 2783.3 - 1.36E+06 - - - -0.2683 - 2.442 0.483 - 704.9 1 2 0 -0.0003 11 0 0 0 3.64E+07 2.44E+07 - - - 5.0236 0.9985 221125_WJC_METTL3_EV_vs_WT_F02.13560.13560.2 0.205 12-Aug K.LTATIWK.N sp|O15226|NKRF_HUMAN 1 831.4854 0.96 13850 13560 2 831.484935 416.75 NF-kappa-B-repressing factor OS=Homo sapiens OX=9606 GN=NKRF PE=1 SV=2 8.75 2783.4 - 1.89E+06 - - - -0.6073 - 1.639 0.198 - 163 1 2 0 -0.0005 7 0 0 0 3.41E+07 3.55E+07 - - - 2.0688 0.9477 221125_WJC_METTL3_EV_vs_WT_F02.13561.13561.2 0.107 12-Sep L.PLQDVYK[136.11].L "sp|Q05639|EF1A2_HUMAN,sp|P68104|EF1A1_HUMAN,sp|Q5VTE0|EF1A3_HUMAN,tr|A0A7I2V659|A0A7I2V659_HUMAN,tr|A0A7I2V3H3|A0A7I2V3H3_HUMAN,tr|A0A2U3TZH3|A0A2U3TZH3_HUMAN,tr|A0A7I2V5N4|A0A7I2V5N4_HUMAN,tr|A0A087WVQ9|A0A087WVQ9_HUMAN,tr|A0A087WV01|A0A087WV01_HUMAN" 9 869.4738 0.49 13851 13561 2 869.4744 435.7442 Elongation factor 1-alpha 2 OS=Homo sapiens OX=9606 GN=EEF1A2 PE=1 SV=1 6.26 2783.5 - 1.56E+06 - - - 0.6682 - 1.927 0.197 - 275.1 1 1 0 0.0006 7 0 0 0 5.16E+07 1.06E+08 - - - 2.5743 0.9886 221125_WJC_METTL3_EV_vs_WT_F02.13562.13562.2 0.603 16-Jun K.EYFDPATVR.Q sp|Q15911|ZFHX3_HUMAN 1 1096.5189 19.76 13852 13562 2 1096.520602 549.2667 Zinc finger homeobox protein 3 OS=Homo sapiens OX=9606 GN=ZFHX3 PE=1 SV=2 4.37 2783.6 - 421012 - - - 1.5294 - 1.041 0.237 - 89.9 1 2 0 0.0017 9 0 0 0 1.31E+07 6.63E+05 - - - 0.9072 0.9999 221125_WJC_METTL3_EV_vs_WT_F02.13563.13563.2 5.94E-06 20-Dec R.LDEEQQVLLSR[166.11].L "sp|Q9HCM9|TRI39_HUMAN,tr|A0A0G2JKY0|A0A0G2JKY0_HUMAN,tr|A0A096LP39|A0A096LP39_HUMAN,tr|A0A140TA46|A0A140TA46_HUMAN,tr|A2AAZ6|A2AAZ6_HUMAN,tr|H0Y735|H0Y735_HUMAN" 6 1338.7019 4.51 13853 13563 2 1338.700434 670.3582 E3 ubiquitin-protein ligase TRIM39 OS=Homo sapiens OX=9606 GN=TRIM39 PE=1 SV=2 4.14 2783.8 - 281907 - - - -1.0689 - 2.562 0.49 - 654.3 1 2 0 -0.0014 11 0 0 0 2.02E+07 4.48E+06 - - - 5.2047 0.9992 221125_WJC_METTL3_EV_vs_WT_F02.13566.13566.2 0.00549 14-Jul R.QYYTLLNK.A "sp|Q9UN86|G3BP2_HUMAN,tr|A0A7I2V3E2|A0A7I2V3E2_HUMAN,tr|A0A7I2V2R0|A0A7I2V2R0_HUMAN,tr|D6RAC7|D6RAC7_HUMAN,tr|D6RGJ4|D6RGJ4_HUMAN,tr|D6RB17|D6RB17_HUMAN,tr|A0A7I2YQS2|A0A7I2YQS2_HUMAN,tr|A0A7I2YQD9|A0A7I2YQD9_HUMAN,tr|D6R9A4|D6R9A4_HUMAN,tr|D6RBR0|D6RBR0_HUMAN,tr|D6RBW8|D6RBW8_HUMAN" 11 1041.5495 1.38 13854 13566 2 1041.549033 521.782 Ras GTPase-activating protein-binding protein 2 OS=Homo sapiens OX=9606 GN=G3BP2 PE=1 SV=2 8.5 2784.2 - 3.65E+07 - - - -0.4445 - 1.368 0.354 - 168 1 2 0 -0.0005 8 0 0 0 8.27E+08 5.98E+08 - - - 2.6005 0.9976 221125_WJC_METTL3_EV_vs_WT_F02.13567.13567.2 7.77 12-Aug R.TLQVLIK.Q "sp|Q7Z3B4|NUP54_HUMAN,sp|P35219|CAH8_HUMAN" 2 813.5324 1.71 13855 13567 2 813.531478 407.7735 Nucleoporin p54 OS=Homo sapiens OX=9606 GN=NUP54 PE=1 SV=2 8.41 2784.2 - 1.12E+07 - - - -1.121 - 1.581 0.181 - 213.6 1 2 0 -0.0009 7 0 0 0 2.58E+08 1.51E+08 - - - 1.829 0.9994 221125_WJC_METTL3_EV_vs_WT_F02.13568.13568.2 0.00641 16-Sep K.IGPLGLSPK[136.11].K sp|P30050|RL12_HUMAN 1 888.5524 1.42 13856 13568 2 888.552211 445.2835 60S ribosomal protein L12 OS=Homo sapiens OX=9606 GN=RPL12 PE=1 SV=1 8.75 2784.3 - 3.44E+06 - - - -0.2161 - 1.706 0.299 - 185.7 1 2 0 -0.0002 9 0 0 0 2.97E+09 2.09E+09 - - - 2.7947 0.9996 221125_WJC_METTL3_EV_vs_WT_F02.13569.13569.2 0.364 14-Sep K.INLIAPPR.Y "sp|P05198|IF2A_HUMAN,tr|H0YJS4|H0YJS4_HUMAN,tr|G3V4T5|G3V4T5_HUMAN" 3 892.5494 1.33 13857 13569 2 892.549561 447.282 Eukaryotic translation initiation factor 2 subunit 1 OS=Homo sapiens OX=9606 GN=EIF2S1 PE=1 SV=3 9.75 2784.3 - 3.03E+06 - - - 0.1389 - 2.027 0.302 - 311.2 1 2 0 0.0001 8 0 0 0 3.77E+08 2.84E+08 - - - 3.4025 0.9996 221125_WJC_METTL3_EV_vs_WT_F02.13570.13570.2 0.0284 14-Aug R.FVVELQQR[166.11].E sp|Q9Y6D9|MD1L1_HUMAN 1 1027.569 1.46 13858 13570 2 1027.5693 514.7918 Mitotic spindle assembly checkpoint protein MAD1 OS=Homo sapiens OX=9606 GN=MAD1L1 PE=1 SV=2 6 2784.4 - 2.72E+06 - - - 0.292 - 1.698 0.348 - 264.6 1 2 0 0.0003 8 0 0 0 1.41E+08 9.68E+07 - - - 3.208 0.9973 221125_WJC_METTL3_EV_vs_WT_F02.13571.13571.2 0.19 12-Sep K.LTATIWK[136.11].N sp|O15226|NKRF_HUMAN 1 839.4996 0.98 13859 13571 2 839.498697 420.7571 NF-kappa-B-repressing factor OS=Homo sapiens OX=9606 GN=NKRF PE=1 SV=2 8.75 2784.5 - 2.00E+06 - - - -1.1233 - 1.408 0.219 - 211.2 1 2 0 -0.0009 7 0 0 0 3.41E+07 3.49E+07 - - - 1.7424 0.9834 221125_WJC_METTL3_EV_vs_WT_F02.13573.13573.2 0.0615 16-Jun K.METAATLLR.R sp|Q15477|SKIV2_HUMAN 1 1004.5325 1.46 13861 13573 2 1004.530936 503.2735 Helicase SKI2W OS=Homo sapiens OX=9606 GN=SKIV2L PE=1 SV=3 5.75 2784.7 - 637636 - - - -1.5231 - 1.443 0.107 - 73.1 5 2 0 -0.0015 9 0 0 0 2.42E+07 1.66E+07 - - - 0.5795 0.9995 221125_WJC_METTL3_EV_vs_WT_F02.13578.13578.2 0.00112 14-Aug R.FVVELQQR.E sp|Q9Y6D9|MD1L1_HUMAN 1 1017.5607 1.46 13864 13578 2 1017.559402 509.7876 Mitotic spindle assembly checkpoint protein MAD1 OS=Homo sapiens OX=9606 GN=MAD1L1 PE=1 SV=2 6 2785.3 - 6.57E+06 - - - -1.3051 - 1.644 0.379 - 233.5 1 2 0 -0.0013 8 0 0 0 1.42E+08 9.69E+07 - - - 3.3392 0.9999 221125_WJC_METTL3_EV_vs_WT_F02.13581.13581.2 13.3 13/24 R.VVLVTGAGAGLGR[166.11].A "sp|P51659|DHB4_HUMAN,tr|A0A2R8YD50|A0A2R8YD50_HUMAN,tr|A0A804HLJ0|A0A804HLJ0_HUMAN,tr|A0A804HIR1|A0A804HIR1_HUMAN,tr|E7ER27|E7ER27_HUMAN,tr|A0A2R8YF45|A0A2R8YF45_HUMAN,tr|E7EPL9|E7EPL9_HUMAN,tr|A0A804HKU2|A0A804HKU2_HUMAN,tr|A0A804HKT2|A0A804HKT2_HUMAN,tr|A0A2R8YDT8|A0A2R8YDT8_HUMAN,tr|A0A804HK65|A0A804HK65_HUMAN,tr|A0A2R8YEG2|A0A2R8YEG2_HUMAN" 12 1178.7011 0.71 13867 13581 2 1178.700437 590.3578 Peroxisomal multifunctional enzyme type 2 OS=Homo sapiens OX=9606 GN=HSD17B4 PE=1 SV=3 9.72 2785.5 - 1.70E+06 - - - -0.543 - 2.426 0.442 - 414.8 1 2 0 -0.0006 13 0 0 0 1.10E+08 1.56E+08 - - - 4.58 0.9984 221125_WJC_METTL3_EV_vs_WT_F02.13582.13582.2 0.15 14-Jul R.QIPFGDVR[166.11].L "sp|P51116|FXR2_HUMAN,tr|I3L1Z2|I3L1Z2_HUMAN" 2 940.5006 1.47 13868 13582 2 940.499268 471.2576 Fragile X mental retardation syndrome-related protein 2 OS=Homo sapiens OX=9606 GN=FXR2 PE=1 SV=2 5.84 2785.6 - 1.62E+06 - - - -1.4014 - 1.261 0.344 - 212.7 1 2 0 -0.0013 8 0 0 0 1.80E+08 1.22E+08 - - - 2.2808 0.9995 221125_WJC_METTL3_EV_vs_WT_F02.13584.13584.2 0.000221 18-Sep R.EIDGGLETLR.L "sp|P38117|ETFB_HUMAN,tr|M0QY67|M0QY67_HUMAN" 2 1101.5666 2.1 13870 13584 2 1101.5685 551.7906 Electron transfer flavoprotein subunit beta OS=Homo sapiens OX=9606 GN=ETFB PE=1 SV=3 4.14 2785.9 - 1.19E+06 - - - 1.7221 - 2.003 0.392 - 276.5 1 2 0 0.0019 10 0 0 0 4.46E+08 2.12E+08 - - - 3.8747 0.9403 221125_WJC_METTL3_EV_vs_WT_F02.13590.13590.2 0.253 12-Sep L.PLQDVYK.L "sp|Q05639|EF1A2_HUMAN,sp|P68104|EF1A1_HUMAN,sp|Q5VTE0|EF1A3_HUMAN,tr|A0A7I2V659|A0A7I2V659_HUMAN,tr|A0A7I2V3H3|A0A7I2V3H3_HUMAN,tr|A0A2U3TZH3|A0A2U3TZH3_HUMAN,tr|A0A7I2V5N4|A0A7I2V5N4_HUMAN,tr|A0A087WVQ9|A0A087WVQ9_HUMAN,tr|A0A087WV01|A0A087WV01_HUMAN" 9 861.4596 0.48 13874 13590 2 861.460331 431.7371 Elongation factor 1-alpha 2 OS=Homo sapiens OX=9606 GN=EEF1A2 PE=1 SV=1 6.26 2786.6 - 1.81E+06 - - - 0.8265 - 1.794 0.218 - 300.7 1 1 0 0.0007 7 0 0 0 5.03E+07 1.05E+08 - - - 2.5028 0.9968 221125_WJC_METTL3_EV_vs_WT_F02.13591.13591.2 0.487 14-Aug K.TALLGLTK.T sp|Q9BTZ2|DHRS4_HUMAN 1 815.5117 1.34 13875 13591 2 815.510494 408.7631 Dehydrogenase\reductase SDR family member 4 OS=Homo sapiens OX=9606 GN=DHRS4 PE=1 SV=3 8.41 2786.6 - 6.89E+06 - - - -1.4224 - 1.497 0.199 - 233.4 1 2 0 -0.0012 8 0 0 0 1.55E+09 1.15E+09 - - - 1.7273 0.9998 221125_WJC_METTL3_EV_vs_WT_F02.13592.13592.2 5.35E-05 24-Dec R.VVLVTGAGAGLGR.A "sp|P51659|DHB4_HUMAN,tr|A0A2R8YD50|A0A2R8YD50_HUMAN,tr|A0A804HLJ0|A0A804HLJ0_HUMAN,tr|A0A804HIR1|A0A804HIR1_HUMAN,tr|E7ER27|E7ER27_HUMAN,tr|A0A2R8YF45|A0A2R8YF45_HUMAN,tr|E7EPL9|E7EPL9_HUMAN,tr|A0A804HKU2|A0A804HKU2_HUMAN,tr|A0A804HKT2|A0A804HKT2_HUMAN,tr|A0A2R8YDT8|A0A2R8YDT8_HUMAN,tr|A0A804HK65|A0A804HK65_HUMAN,tr|A0A2R8YEG2|A0A2R8YEG2_HUMAN" 12 1168.6928 0.69 13876 13592 2 1168.693195 585.3537 Peroxisomal multifunctional enzyme type 2 OS=Homo sapiens OX=9606 GN=HSD17B4 PE=1 SV=3 9.72 2786.8 - 1.45E+06 - - - 0.332 - 2.643 0.408 - 519.1 1 2 0 0.0004 13 0 0 0 1.08E+08 1.56E+08 - - - 4.5488 0.9596 221125_WJC_METTL3_EV_vs_WT_F02.13594.13594.2 2.4 16-Jul R.APEILLGC[160.03]K.Y "sp|P24941|CDK2_HUMAN,tr|G3V5T9|G3V5T9_HUMAN" 2 999.5423 10.37 13878 13594 2 999.541383 500.7784 Cyclin-dependent kinase 2 OS=Homo sapiens OX=9606 GN=CDK2 PE=1 SV=2 6.04 2787 - 747592 - - - -0.9204 - 1.301 0.07 - 80.5 15 2 0 -0.0009 9 0 0 0 7.42E+07 7.16E+06 - - - -0.2064 0.9864 221125_WJC_METTL3_EV_vs_WT_F02.13599.13599.2 11.8 14-Jun K.TVFDEAIR.A "sp|P63000|RAC1_HUMAN,sp|P60763|RAC3_HUMAN,sp|P15153|RAC2_HUMAN,tr|B1AH77|B1AH77_HUMAN,tr|J3KSC4|J3KSC4_HUMAN,tr|J3QLK0|J3QLK0_HUMAN,tr|B1AH80|B1AH80_HUMAN" 7 949.4869 0.87 13881 13599 2 949.486553 475.7507 Ras-related C3 botulinum toxin substrate 1 OS=Homo sapiens OX=9606 GN=RAC1 PE=1 SV=1 4.37 2787.6 - 1.78E+07 - - - -0.3612 - 1.242 0.098 - 112.8 1 2 0 -0.0003 8 0 0 0 3.74E+08 4.33E+08 - - - 0.4183 0.9948 221125_WJC_METTL3_EV_vs_WT_F02.13601.13601.2 0.0157 14-Jun R.LQMFDDPR.N "sp|P52732|KIF11_HUMAN,tr|A0A7I2YQY4|A0A7I2YQY4_HUMAN,tr|A0A7I2V3A9|A0A7I2V3A9_HUMAN,tr|A0A7I2V3V3|A0A7I2V3V3_HUMAN" 4 1020.4699 4.31 13883 13601 2 1020.466869 511.2422 Kinesin-like protein KIF11 OS=Homo sapiens OX=9606 GN=KIF11 PE=1 SV=2 4.21 2787.7 - 6.23E+06 - - - -2.9369 - 1.072 0.399 - 123.3 1 2 0 -0.003 8 0 0 0 2.00E+09 4.64E+08 - - - 2.1968 0.9994 221125_WJC_METTL3_EV_vs_WT_F02.13605.13605.2 0.00131 14-Aug K.VTLLLSSK.T "sp|Q9NTZ6|RBM12_HUMAN,tr|A6PVI0|A6PVI0_HUMAN,tr|Q5JX62|Q5JX62_HUMAN,tr|A6PVI1|A6PVI1_HUMAN" 4 859.5379 1.24 13887 13605 2 859.536882 430.7762 RNA-binding protein 12 OS=Homo sapiens OX=9606 GN=RBM12 PE=1 SV=1 8.72 2787.9 - 1.27E+06 - - - -1.1483 - 1.658 0.347 - 200.4 1 2 0 -0.001 8 0 0 0 5.23E+07 4.20E+07 - - - 3.1285 0.9988 221125_WJC_METTL3_EV_vs_WT_F02.13606.13606.2 0.0409 20-Sep R.AVLGDDPQLMK[136.11].V sp|Q9Y6J9|TAF6L_HUMAN 1 1193.6206 1.2 13888 13606 2 1193.618888 597.8176 TAF6-like RNA polymerase II p300\CBP-associated factor-associated factor 65 kDa subunit 6L OS=Homo sapiens OX=9606 GN=TAF6L PE=1 SV=1 4.21 2788.1 - 1.18E+06 - - - -1.3999 - 1.792 0.265 - 244.8 1 2 0 -0.0017 11 0 0 0 4.62E+07 3.84E+07 - - - 2.5758 0.997 221125_WJC_METTL3_EV_vs_WT_F02.13607.13607.2 0.00205 14-Oct R.LYQELQIR.N "sp|Q96KQ4|ASPP1_HUMAN,tr|A0A3B3ISJ2|A0A3B3ISJ2_HUMAN" 2 1061.5869 7.54 13889 13607 2 1061.588345 531.8007 Apoptosis-stimulating of p53 protein 1 OS=Homo sapiens OX=9606 GN=PPP1R13B PE=1 SV=3 6 2788.2 - 1.04E+06 - - - 1.3188 - 1.687 0.164 - 407 1 2 0 0.0014 8 0 0 0 1.93E+07 2.55E+06 - - - 1.8291 0.954 221125_WJC_METTL3_EV_vs_WT_F02.13610.13610.2 0.556 14-May R.LQMFDDPR[166.11].N "sp|P52732|KIF11_HUMAN,tr|A0A7I2YQY4|A0A7I2YQY4_HUMAN,tr|A0A7I2V3A9|A0A7I2V3A9_HUMAN,tr|A0A7I2V3V3|A0A7I2V3V3_HUMAN" 4 1030.4781 4.31 13890 13610 2 1030.474486 516.2463 Kinesin-like protein KIF11 OS=Homo sapiens OX=9606 GN=KIF11 PE=1 SV=2 4.21 2788.6 - 3.15E+06 - - - -3.542 - 0.959 0.262 - 89.5 1 2 0 -0.0037 8 0 0 0 2.00E+09 4.64E+08 - - - 0.8487 0.9995 221125_WJC_METTL3_EV_vs_WT_F02.13611.13611.2 0.0451 16-Oct R.VFNYNTLER.V "sp|P35606|COPB2_HUMAN,tr|H0Y938|H0Y938_HUMAN,tr|A0A7I2V3G0|A0A7I2V3G0_HUMAN,tr|D6RBZ7|D6RBZ7_HUMAN,tr|A0A7I2V258|A0A7I2V258_HUMAN,tr|D6R997|D6R997_HUMAN,tr|D6RBT6|D6RBT6_HUMAN,tr|H0YAC7|H0YAC7_HUMAN,tr|D6RBG7|D6RBG7_HUMAN,tr|A0A7I2YQF9|A0A7I2YQF9_HUMAN,tr|D6RCL6|D6RCL6_HUMAN" 11 1154.572 1.01 13891 13611 2 1154.572759 578.2933 Coatomer subunit beta' OS=Homo sapiens OX=9606 GN=COPB2 PE=1 SV=2 5.97 2788.7 - 1.83E+06 - - - 0.6375 - 1.798 0.327 - 300.8 1 2 0 0.0007 9 0 0 0 8.39E+07 8.28E+07 - - - 3.1533 0.997 221125_WJC_METTL3_EV_vs_WT_F02.13612.13612.2 0.478 12-Jul R.FSTIDLR.A "sp|O60524|NEMF_HUMAN,tr|G3V547|G3V547_HUMAN,tr|G3V5V3|G3V5V3_HUMAN,tr|G3V4D9|G3V4D9_HUMAN" 4 850.4549 0.55 13892 13612 2 850.454216 426.2347 Nuclear export mediator factor NEMF OS=Homo sapiens OX=9606 GN=NEMF PE=1 SV=4 5.84 2788.8 - 751438 - - - -0.7666 - 1.501 0.165 - 173.2 1 2 0 -0.0007 7 0 0 0 1.85E+07 3.35E+07 - - - 1.5463 0.8173 221125_WJC_METTL3_EV_vs_WT_F02.13613.13613.2 0.731 14-Oct A.SPATVQSR.Q sp|Q9C075|K1C23_HUMAN 1 844.4403 17.42 13893 13613 2 844.439944 423.2274 "Keratin, type I cytoskeletal 23 OS=Homo sapiens OX=9606 GN=KRT23 PE=1 SV=2" 9.47 2788.9 - 623637 - - - -0.3979 - 1.568 0.126 - 345.5 1 1 0 -0.0003 8 0 0 0 1.75E+07 1.00E+06 - - - 1.3281 0.9881 221125_WJC_METTL3_EV_vs_WT_F02.13616.13616.2 0.00188 16-Sep R.QVTC[160.03]VAWVR[166.11].C sp|Q13610|PWP1_HUMAN 1 1127.5785 0.48 13894 13616 2 1127.572983 564.7965 Periodic tryptophan protein 1 homolog OS=Homo sapiens OX=9606 GN=PWP1 PE=1 SV=1 8.25 2789.3 - 1.44E+06 - - - -4.9096 - 1.935 0.242 - 306.6 1 2 0 -0.0055 9 0 0 0 2.43E+07 5.01E+07 - - - 2.7364 0.9902 221125_WJC_METTL3_EV_vs_WT_F02.13617.13617.2 0.297 16-Jun R.ANTFVAELK.G "sp|P40926|MDHM_HUMAN,tr|G3XAL0|G3XAL0_HUMAN" 2 991.5338 1.17 13895 13617 2 991.531942 496.7742 "Malate dehydrogenase, mitochondrial OS=Homo sapiens OX=9606 GN=MDH2 PE=1 SV=3" 6.05 2789.4 - 4.32E+06 - - - -1.9203 - 1.216 0.224 - 75.4 2 2 0 -0.0019 9 0 0 0 8.81E+07 7.55E+07 - - - 1.1262 0.9977 221125_WJC_METTL3_EV_vs_WT_F02.13618.13618.2 0.0269 14-Jul R.GPIQILNR[166.11].Q "sp|P30876|RPB2_HUMAN,tr|C9J4M6|C9J4M6_HUMAN,tr|C9J2Y9|C9J2Y9_HUMAN" 3 919.5479 1.18 13896 13618 2 919.547221 460.7812 DNA-directed RNA polymerase II subunit RPB2 OS=Homo sapiens OX=9606 GN=POLR2B PE=1 SV=1 9.75 2789.4 - 1.38E+06 - - - -0.7058 - 1.529 0.191 - 188.3 1 2 0 -0.0006 8 0 0 0 5.59E+07 4.75E+07 - - - 1.7321 0.9998 221125_WJC_METTL3_EV_vs_WT_F02.13620.13620.2 6.31E-06 16-Aug K.MPEC[160.03]YFYSK.F "sp|O95639|CPSF4_HUMAN,sp|A6NMK7|CPS4L_HUMAN,tr|C9K0K2|C9K0K2_HUMAN,tr|B7Z7B0|B7Z7B0_HUMAN,tr|H7C016|H7C016_HUMAN,tr|H9KVA5|H9KVA5_HUMAN,tr|C9JEV9|C9JEV9_HUMAN" 7 1223.4991 1.45 13898 13620 2 1223.497923 612.7568 Cleavage and polyadenylation specificity factor subunit 4 OS=Homo sapiens OX=9606 GN=CPSF4 PE=1 SV=1 5.75 2789.7 - 595628 - - - -0.9759 - 1.799 0.496 - 241.4 1 2 0 -0.0012 9 0 0 0 2.04E+07 1.40E+07 - - - 4.403 0.9995 221125_WJC_METTL3_EV_vs_WT_F02.13622.13622.2 0.00296 14-Jul R.LPLQDVYK[136.11].L "sp|Q05639|EF1A2_HUMAN,sp|P68104|EF1A1_HUMAN,sp|Q5VTE0|EF1A3_HUMAN,tr|A0A7I2V659|A0A7I2V659_HUMAN,tr|A0A7I2V3H3|A0A7I2V3H3_HUMAN,tr|A0A2U3TZH3|A0A2U3TZH3_HUMAN,tr|A0A7I2V5N4|A0A7I2V5N4_HUMAN,tr|A0A087WVQ9|A0A087WVQ9_HUMAN,tr|A0A087WV01|A0A087WV01_HUMAN" 9 982.5579 0.37 13899 13622 2 982.556819 492.2862 Elongation factor 1-alpha 2 OS=Homo sapiens OX=9606 GN=EEF1A2 PE=1 SV=1 5.83 2789.9 - 1.95E+08 - - - -1.0829 - 1.653 0.373 - 222.3 1 2 0 -0.0011 8 0 0 0 2.83E+09 7.65E+09 - - - 3.3114 0.9998 221125_WJC_METTL3_EV_vs_WT_F02.13624.13624.2 2.03E-07 16-Oct R.VFNYNTLER[166.11].V "sp|P35606|COPB2_HUMAN,tr|H0Y938|H0Y938_HUMAN,tr|A0A7I2V3G0|A0A7I2V3G0_HUMAN,tr|D6RBZ7|D6RBZ7_HUMAN,tr|A0A7I2V258|A0A7I2V258_HUMAN,tr|D6R997|D6R997_HUMAN,tr|D6RBT6|D6RBT6_HUMAN,tr|H0YAC7|H0YAC7_HUMAN,tr|D6RBG7|D6RBG7_HUMAN,tr|A0A7I2YQF9|A0A7I2YQF9_HUMAN,tr|D6RCL6|D6RCL6_HUMAN" 11 1164.5803 1.01 13900 13624 2 1164.579127 583.2974 Coatomer subunit beta' OS=Homo sapiens OX=9606 GN=COPB2 PE=1 SV=2 5.97 2790.1 - 3.23E+06 - - - -1.0012 - 2.055 0.394 - 383.7 1 2 0 -0.0012 9 0 0 0 8.39E+07 8.28E+07 - - - 4.0345 0.9806 221125_WJC_METTL3_EV_vs_WT_F02.13627.13627.2 0.704 16-Jul R.TIDEHDAII.- "sp|Q8N131|PORIM_HUMAN,tr|E9PKT4|E9PKT4_HUMAN" 2 1025.5029 - 13902 13627 2 1025.501855 513.7587 Porimin OS=Homo sapiens OX=9606 GN=TMEM123 PE=1 SV=1 4.02 2790.4 - 2.11E+06 - - - -1.058 - 0.813 0.253 - 92.4 1 2 0 -0.0011 9 0 0 0 - - - - - 0.3104 0.9998 221125_WJC_METTL3_EV_vs_WT_F02.13628.13628.2 5.30E-05 13/20 K.LMADVVEEETR.R "sp|Q9NPI6|DCP1A_HUMAN,tr|A0A087WT55|A0A087WT55_HUMAN,tr|A0A087WVE6|A0A087WVE6_HUMAN" 3 1290.6126 2.85 13903 13628 2 1290.610502 646.3136 mRNA-decapping enzyme 1A OS=Homo sapiens OX=9606 GN=DCP1A PE=1 SV=3 4 2790.6 - 788359 - - - -1.6 - 1.995 0.542 - 522 1 2 0 -0.0021 11 0 0 0 2.60E+07 9.11E+06 - - - 4.9119 0.9999 221125_WJC_METTL3_EV_vs_WT_F02.13633.13633.2 7.83E-05 13/22 K.GVLMYGPPGTGK[136.11].T "sp|P17980|PRS6A_HUMAN,tr|R4GNH3|R4GNH3_HUMAN,tr|E9PMD8|E9PMD8_HUMAN,tr|E9PKD5|E9PKD5_HUMAN,tr|E9PM69|E9PM69_HUMAN,tr|E9PN50|E9PN50_HUMAN" 6 1183.6151 5.37 13906 13633 2 1183.614559 592.8148 26S proteasome regulatory subunit 6A OS=Homo sapiens OX=9606 GN=PSMC3 PE=1 SV=3 8.59 2791.2 - 1.28E+06 - - - -0.4402 - 2.43 0.494 - 568.5 1 2 0 -0.0005 12 0 0 0 2.44E+08 4.55E+07 - - - 5.0257 0.9989 221125_WJC_METTL3_EV_vs_WT_F02.13637.13637.2 0.024 16-Aug R.ELNEALELK[136.11].D "sp|P04637|P53_HUMAN,tr|A0A087X1Q1|A0A087X1Q1_HUMAN,tr|A0A0U1RQC9|A0A0U1RQC9_HUMAN" 3 1065.5797 0.88 13908 13637 2 1065.579447 533.7971 Cellular tumor antigen p53 OS=Homo sapiens OX=9606 GN=TP53 PE=1 SV=4 4.25 2791.7 - 4.64E+06 - - - -0.275 - 1.594 0.255 - 254.5 1 2 0 -0.0003 9 0 0 0 1.71E+08 1.95E+08 - - - 2.2732 0.9988 221125_WJC_METTL3_EV_vs_WT_F02.13638.13638.2 0.184 14-Aug K.ALEAVFGK.Y "sp|P38159|RBMX_HUMAN,tr|H3BT71|H3BT71_HUMAN,tr|H0Y6E7|H0Y6E7_HUMAN,tr|H3BR27|H3BR27_HUMAN,tr|H3BNC1|H3BNC1_HUMAN" 5 833.4647 1.47 13909 13638 2 833.463562 417.7396 "RNA-binding motif protein, X chromosome OS=Homo sapiens OX=9606 GN=RBMX PE=1 SV=3" 6.05 2791.8 - 1.40E+06 - - - -1.3702 - 1.499 0.307 - 254 1 2 0 -0.0011 8 0 0 0 2.24E+09 1.52E+09 - - - 2.529 0.9998 221125_WJC_METTL3_EV_vs_WT_F02.13639.13639.2 2.87E-05 24-Dec K.MLQGESAEAFVAK.H sp|Q9NYH9|UTP6_HUMAN 1 1379.6755 1.41 13910 13639 2 1379.673671 690.845 U3 small nucleolar RNA-associated protein 6 homolog OS=Homo sapiens OX=9606 GN=UTP6 PE=1 SV=2 4.53 2791.9 - 397056 - - - -1.3271 - 1.999 0.512 - 296.9 1 2 0 -0.0018 13 0 0 0 1.12E+07 7.92E+06 - - - 4.5998 0.8038 221125_WJC_METTL3_EV_vs_WT_F02.13642.13642.2 0.16 12-Apr K.C[160.03]EFQDAY.V "sp|P10809|CH60_HUMAN,tr|A0A7I2V2X6|A0A7I2V2X6_HUMAN,tr|A0A7I2YQK6|A0A7I2YQK6_HUMAN,tr|A0A7I2V599|A0A7I2V599_HUMAN,tr|A0A7I2YQ71|A0A7I2YQ71_HUMAN,tr|A0A7I2V5M1|A0A7I2V5M1_HUMAN,tr|A0A7I2V5K3|A0A7I2V5K3_HUMAN,tr|A0A7I2V369|A0A7I2V369_HUMAN" 8 931.3382 - 13911 13642 2 931.337377 466.6764 "60 kDa heat shock protein, mitochondrial OS=Homo sapiens OX=9606 GN=HSPD1 PE=1 SV=2" 3.67 2792.3 - 3.09E+06 - - - -0.8654 - 0.938 0.34 - 72.6 1 1 0 -0.0008 7 0 0 0 - - - - - 1.3492 0.9997 221125_WJC_METTL3_EV_vs_WT_F02.13643.13643.2 0.000286 18-Oct K.YLGQDYEQLR.V "sp|P07384|CAN1_HUMAN,tr|E9PJA6|E9PJA6_HUMAN,tr|E9PIA9|E9PIA9_HUMAN,tr|E9PLX0|E9PLX0_HUMAN,tr|E9PQB3|E9PQB3_HUMAN,tr|E9PMC6|E9PMC6_HUMAN,tr|E9PSA6|E9PSA6_HUMAN,tr|E9PLC9|E9PLC9_HUMAN,tr|E9PJJ3|E9PJJ3_HUMAN,tr|E9PRM1|E9PRM1_HUMAN" 10 1283.6146 1.84 13912 13643 2 1283.613507 642.8146 Calpain-1 catalytic subunit OS=Homo sapiens OX=9606 GN=CAPN1 PE=1 SV=1 4.37 2792.4 - 1.41E+06 - - - -0.864 - 1.483 0.475 - 254.8 1 2 0 -0.0011 10 0 0 0 3.71E+07 2.02E+07 - - - 3.649 0.9555 221125_WJC_METTL3_EV_vs_WT_F02.13644.13644.2 0.000739 16-Aug Q.GLPEGVAFK.H "sp|P78347|GTF2I_HUMAN,tr|A0A494C1K3|A0A494C1K3_HUMAN" 2 916.5018 1.86 13913 13644 2 916.500494 459.2582 General transcription factor II-I OS=Homo sapiens OX=9606 GN=GTF2I PE=1 SV=2 6 2792.5 - 1.35E+06 - - - -1.4446 - 1.462 0.386 - 168.9 1 1 0 -0.0013 9 0 0 0 4.75E+07 2.56E+07 - - - 2.9904 0.9998 221125_WJC_METTL3_EV_vs_WT_F02.13650.13650.2 0.000337 18-Sep R.EIDGGLETLR[166.11].L "sp|P38117|ETFB_HUMAN,tr|M0QY67|M0QY67_HUMAN" 2 1111.5749 2.1 13917 13650 2 1111.574006 556.7947 Electron transfer flavoprotein subunit beta OS=Homo sapiens OX=9606 GN=ETFB PE=1 SV=3 4.14 2793.2 - 8.39E+06 - - - -0.78 - 1.965 0.482 - 336.1 1 2 0 -0.0009 10 0 0 0 4.46E+08 2.12E+08 - - - 4.4863 0.9538 221125_WJC_METTL3_EV_vs_WT_F02.13651.13651.2 0.975 14-Jun K.VTLLLSSK[136.11].T "sp|Q9NTZ6|RBM12_HUMAN,tr|A6PVI0|A6PVI0_HUMAN,tr|Q5JX62|Q5JX62_HUMAN,tr|A6PVI1|A6PVI1_HUMAN" 4 867.5521 1.25 13918 13651 2 867.550487 434.7833 RNA-binding protein 12 OS=Homo sapiens OX=9606 GN=RBM12 PE=1 SV=1 8.72 2793.3 - 1.91E+06 - - - -1.8235 - 1.311 0.022 - 127.6 1 2 0 -0.0016 8 0 0 0 5.23E+07 4.19E+07 - - - 0.0197 0.9879 221125_WJC_METTL3_EV_vs_WT_F02.13652.13652.2 2.74 16-Jul K.IGDFGLATK.V sp|P53350|PLK1_HUMAN 1 920.4967 0.95 13919 13652 2 920.496843 461.2556 Serine\threonine-protein kinase PLK1 OS=Homo sapiens OX=9606 GN=PLK1 PE=1 SV=1 5.84 2793.4 - 1.18E+06 - - - 0.1195 - 1.204 0.124 - 82.5 1 2 0 0.0001 9 0 0 0 2.38E+07 2.50E+07 - - - 0.4939 0.9996 221125_WJC_METTL3_EV_vs_WT_F02.13653.13653.2 9.52E-07 20-Dec K.IGEGGFGC[160.03]VYR.A "sp|P51617|IRAK1_HUMAN,tr|F8WAB6|F8WAB6_HUMAN,tr|D3YTB5|D3YTB5_HUMAN" 3 1213.555 1.83 13920 13653 2 1213.551597 607.7848 Interleukin-1 receptor-associated kinase 1 OS=Homo sapiens OX=9606 GN=IRAK1 PE=1 SV=2 5.99 2793.5 - 700787 - - - -2.7984 - 2.267 0.545 - 399.9 1 2 0 -0.0034 11 0 0 0 2.19E+07 1.20E+07 - - - 5.2794 0.9998 221125_WJC_METTL3_EV_vs_WT_F02.13654.13654.2 2.10E-05 24-Nov K.MLQGESAEAFVAK[136.11].H sp|Q9NYH9|UTP6_HUMAN 1 1387.6897 1.41 13921 13654 2 1387.687336 694.8521 U3 small nucleolar RNA-associated protein 6 homolog OS=Homo sapiens OX=9606 GN=UTP6 PE=1 SV=2 4.53 2793.6 - 308085 - - - -1.705 - 2.354 0.559 - 274.9 1 2 0 -0.0024 13 0 0 0 1.12E+07 7.92E+06 - - - 5.3663 0.9991 221125_WJC_METTL3_EV_vs_WT_F02.13657.13657.2 0.0369 16-Sep R.ELNEALELK.D "sp|P04637|P53_HUMAN,tr|A0A087X1Q1|A0A087X1Q1_HUMAN,tr|A0A0U1RQC9|A0A0U1RQC9_HUMAN" 3 1057.5655 0.88 13922 13657 2 1057.565007 529.79 Cellular tumor antigen p53 OS=Homo sapiens OX=9606 GN=TP53 PE=1 SV=4 4.25 2794 - 6.38E+06 - - - -0.504 - 1.424 0.324 - 195.9 1 2 0 -0.0005 9 0 0 0 1.71E+08 1.95E+08 - - - 2.4565 0.9854 221125_WJC_METTL3_EV_vs_WT_F02.13660.13660.2 0.00581 18-Sep K.VLEQIMDSPR[166.11].Q sp|Q6NSI4|RADX_HUMAN 1 1196.6099 2.19 13925 13660 2 1196.601718 599.3122 RPA-related protein RADX OS=Homo sapiens OX=9606 GN=RADX PE=1 SV=2 4.37 2794.3 - 440478 - - - -6.8193 - 2.049 0.396 - 262.4 1 2 0 -0.0082 10 0 0 0 1.21E+07 5.52E+06 - - - 3.9656 0.9998 221125_WJC_METTL3_EV_vs_WT_F02.13665.13665.2 0.0111 20-Nov K.GLALSNSDVIR.Q "sp|Q9Y5K5|UCHL5_HUMAN,tr|Q5LJA9|Q5LJA9_HUMAN,tr|H0Y6Y4|H0Y6Y4_HUMAN,tr|Q5LJB0|Q5LJB0_HUMAN,tr|Q5LJA5|Q5LJA5_HUMAN" 5 1143.6248 1.81 13928 13665 2 1143.624026 572.8197 Ubiquitin carboxyl-terminal hydrolase isozyme L5 OS=Homo sapiens OX=9606 GN=UCHL5 PE=1 SV=3 5.84 2794.9 - 1.87E+06 - - - -0.6654 - 2.372 0.394 - 588.3 1 2 0 -0.0008 11 0 0 0 5.50E+08 3.04E+08 - - - 4.2874 0.9793 221125_WJC_METTL3_EV_vs_WT_F02.13666.13666.2 6.27E-05 18-Nov Y.LTNEGIQYLR.D "sp|P46783|RS10_HUMAN,tr|A0A2R8Y6L3|A0A2R8Y6L3_HUMAN,tr|F6U211|F6U211_HUMAN,tr|A0A1W2PQS6|A0A1W2PQS6_HUMAN,tr|A0A2R8YFH6|A0A2R8YFH6_HUMAN,tr|A0A2R8Y7H1|A0A2R8Y7H1_HUMAN,tr|S4R435|S4R435_HUMAN" 7 1205.6404 1.16 13929 13666 2 1205.642888 603.8275 40S ribosomal protein S10 OS=Homo sapiens OX=9606 GN=RPS10 PE=1 SV=1 6 2795 - 1.30E+06 - - - 2.0329 - 2.31 0.424 - 565.1 1 1 0 0.0025 10 0 0 0 7.95E+07 6.88E+07 - - - 4.5089 0.9997 221125_WJC_METTL3_EV_vs_WT_F02.13670.13670.2 2.94E-05 18-Sep K.EVFEDAAEIR[166.11].L "sp|P19338|NUCL_HUMAN,tr|A0A7I2V506|A0A7I2V506_HUMAN,tr|A0A7I2V2U7|A0A7I2V2U7_HUMAN,tr|A0A7I2V3F3|A0A7I2V3F3_HUMAN,tr|A0A7I2V428|A0A7I2V428_HUMAN,tr|A0A7I2V349|A0A7I2V349_HUMAN,tr|H7BY16|H7BY16_HUMAN,tr|A0A7I2V5M5|A0A7I2V5M5_HUMAN,tr|C9JLB1|C9JLB1_HUMAN" 9 1187.5698 1.18 13931 13670 2 1187.567666 594.7922 Nucleolin OS=Homo sapiens OX=9606 GN=NCL PE=1 SV=3 4 2795.5 - 2.05E+06 - - - -1.7868 - 1.813 0.507 - 288 1 2 0 -0.0021 10 0 0 0 7.89E+08 6.66E+08 - - - 4.4458 0.9998 221125_WJC_METTL3_EV_vs_WT_F02.13672.13672.2 6.87E-05 18-Sep K.EVFEDAAEIR.L "sp|P19338|NUCL_HUMAN,tr|A0A7I2V506|A0A7I2V506_HUMAN,tr|A0A7I2V2U7|A0A7I2V2U7_HUMAN,tr|A0A7I2V3F3|A0A7I2V3F3_HUMAN,tr|A0A7I2V428|A0A7I2V428_HUMAN,tr|A0A7I2V349|A0A7I2V349_HUMAN,tr|H7BY16|H7BY16_HUMAN,tr|A0A7I2V5M5|A0A7I2V5M5_HUMAN,tr|C9JLB1|C9JLB1_HUMAN" 9 1177.5615 1.18 13933 13672 2 1177.560257 589.788 Nucleolin OS=Homo sapiens OX=9606 GN=NCL PE=1 SV=3 4 2795.7 - 1.55E+06 - - - -1.0709 - 1.812 0.467 - 310.9 1 2 0 -0.0013 10 0 0 0 7.89E+08 6.66E+08 - - - 4.1491 0.9995 221125_WJC_METTL3_EV_vs_WT_F02.13683.13683.2 0.000493 18-Sep K.DVNAAIATIK.T "sp|Q6PEY2|TBA3E_HUMAN,sp|P0DPH7|TBA3C_HUMAN,sp|Q71U36|TBA1A_HUMAN,sp|P0DPH8|TBA3D_HUMAN,sp|P68363|TBA1B_HUMAN,sp|Q9BQE3|TBA1C_HUMAN,tr|A0A1W2PQM2|A0A1W2PQM2_HUMAN,tr|F5H5D3|F5H5D3_HUMAN" 8 1014.571 0.55 13940 13683 2 1014.570829 508.2928 Tubulin alpha-3E chain OS=Homo sapiens OX=9606 GN=TUBA3E PE=1 SV=2 5.84 2796.9 - 2.51E+06 - - - -0.1291 - 1.486 0.378 - 208.2 1 2 0 -0.0001 10 0 0 0 6.18E+07 1.13E+08 - - - 2.9385 0.9994 221125_WJC_METTL3_EV_vs_WT_F02.13684.13684.2 0.00829 16-Aug K.IYFMAGSSR[166.11].K "sp|P14625|ENPL_HUMAN,tr|A0A7P0T917|A0A7P0T917_HUMAN,tr|A0A7P0T823|A0A7P0T823_HUMAN,tr|A0A7P0TAE1|A0A7P0TAE1_HUMAN,tr|H0YIV0|H0YIV0_HUMAN,tr|A0A7P0TAY2|A0A7P0TAY2_HUMAN,tr|A0A087WT78|A0A087WT78_HUMAN,tr|A0A7P0TAT8|A0A7P0TAT8_HUMAN" 8 1040.4989 0.13 13941 13684 2 1040.498502 521.2567 Endoplasmin OS=Homo sapiens OX=9606 GN=HSP90B1 PE=1 SV=1 8.75 2796.9 - 2.57E+06 - - - -0.3546 - 1.513 0.349 - 190.7 1 2 0 -0.0004 9 0 0 0 9.47E+06 7.12E+07 - - - 2.8166 0.9884 221125_WJC_METTL3_EV_vs_WT_F02.13685.13685.2 3.22 12-Jul K.NLLAQIK.S sp|Q92830|KAT2A_HUMAN 1 798.4963 1.17 13942 13685 2 798.49534 400.2554 Histone acetyltransferase KAT2A OS=Homo sapiens OX=9606 GN=KAT2A PE=1 SV=3 8.75 2797.1 - 760113 - - - -1.2511 - 1.251 0.131 - 163.6 1 2 0 -0.001 7 0 0 0 2.70E+07 2.32E+07 - - - 0.7178 0.9729 221125_WJC_METTL3_EV_vs_WT_F02.13686.13686.2 0.849 14-Jul R.VTWAPGLK.N sp|Q6P4I2|WDR73_HUMAN 1 870.4963 0.58 13943 13686 2 870.498548 436.2554 WD repeat-containing protein 73 OS=Homo sapiens OX=9606 GN=WDR73 PE=1 SV=1 8.72 2797.2 - 614851 - - - 2.5376 - 1.234 0.145 - 133.4 1 2 0 0.0022 8 0 0 0 1.02E+07 1.75E+07 - - - 0.7454 0.9996 221125_WJC_METTL3_EV_vs_WT_F02.13688.13688.2 0.019 13/20 K.LADQSGLDVIR[166.11].L "sp|Q8N983|RM43_HUMAN,tr|B1AL05|B1AL05_HUMAN,tr|H0YBU8|H0YBU8_HUMAN,tr|H0Y6Y8|H0Y6Y8_HUMAN" 4 1195.6436 1.08 13945 13688 2 1195.645253 598.8291 "39S ribosomal protein L43, mitochondrial OS=Homo sapiens OX=9606 GN=MRPL43 PE=1 SV=1" 4.21 2797.5 - 463854 - - - 1.365 - 2.469 0.319 - 630.2 1 2 0 0.0016 11 0 0 0 4.99E+07 4.63E+07 - - - 3.8417 0.9998 221125_WJC_METTL3_EV_vs_WT_F02.13692.13692.2 0.0203 20-Nov K.GLALSNSDVIR[166.11].Q "sp|Q9Y5K5|UCHL5_HUMAN,tr|Q5LJA9|Q5LJA9_HUMAN,tr|H0Y6Y4|H0Y6Y4_HUMAN,tr|Q5LJB0|Q5LJB0_HUMAN,tr|Q5LJA5|Q5LJA5_HUMAN" 5 1153.6331 1.8 13947 13692 2 1153.632008 577.8238 Ubiquitin carboxyl-terminal hydrolase isozyme L5 OS=Homo sapiens OX=9606 GN=UCHL5 PE=1 SV=3 5.84 2798 - 7.47E+06 - - - -0.9093 - 2.575 0.386 - 520.9 1 2 0 -0.001 11 0 0 0 5.48E+08 3.04E+08 - - - 4.4504 0.9846 221125_WJC_METTL3_EV_vs_WT_F02.13693.13693.2 0.000161 18-Sep Y.LTNEGIQYLR[166.11].D "sp|P46783|RS10_HUMAN,tr|A0A2R8Y6L3|A0A2R8Y6L3_HUMAN,tr|F6U211|F6U211_HUMAN,tr|A0A1W2PQS6|A0A1W2PQS6_HUMAN,tr|A0A2R8YFH6|A0A2R8YFH6_HUMAN,tr|A0A2R8Y7H1|A0A2R8Y7H1_HUMAN,tr|S4R435|S4R435_HUMAN" 7 1215.6487 1.16 13948 13693 2 1215.648246 608.8316 40S ribosomal protein S10 OS=Homo sapiens OX=9606 GN=RPS10 PE=1 SV=1 6 2798 - 2.60E+06 - - - -0.3792 - 2.043 0.368 - 284.9 1 1 0 -0.0005 10 0 0 0 7.95E+07 6.88E+07 - - - 3.7531 0.9993 221125_WJC_METTL3_EV_vs_WT_F02.13694.13694.2 0.0151 14-Sep K.TTLVIMER.L "sp|Q14974|IMB1_HUMAN,tr|J3QKQ5|J3QKQ5_HUMAN,tr|J3KTM9|J3KTM9_HUMAN" 3 961.5267 1.17 13949 13694 2 961.525038 481.7706 Importin subunit beta-1 OS=Homo sapiens OX=9606 GN=KPNB1 PE=1 SV=2 5.66 2798.1 - 1.91E+06 - - - -1.6796 - 1.775 0.336 - 309.6 1 2 0 -0.0016 8 0 0 0 2.08E+08 1.77E+08 - - - 3.2527 0.9993 221125_WJC_METTL3_EV_vs_WT_F02.13695.13695.2 2.90E-05 14-Aug R.MNYFQVAK[136.11].T "sp|Q93009|UBP7_HUMAN,tr|A0A669KBL1|A0A669KBL1_HUMAN,tr|H3BND8|H3BND8_HUMAN" 3 1007.499 1.02 13950 13695 2 1007.496477 504.7568 Ubiquitin carboxyl-terminal hydrolase 7 OS=Homo sapiens OX=9606 GN=USP7 PE=1 SV=2 8.34 2798.2 - 1.32E+06 - - - -2.4923 - 1.594 0.465 - 208.2 1 2 0 -0.0025 8 0 0 0 3.74E+07 3.67E+07 - - - 3.8809 0.9992 221125_WJC_METTL3_EV_vs_WT_F02.13696.13696.2 0.000827 18-Nov K.FSDSYASVIK[136.11].A "sp|P17812|PYRG1_HUMAN,tr|A0A3B3ITF6|A0A3B3ITF6_HUMAN,tr|B4E1E0|B4E1E0_HUMAN,tr|A0A3B3IRQ8|A0A3B3IRQ8_HUMAN,tr|A0A3B3ITB8|A0A3B3ITB8_HUMAN,tr|A0A3B3IRI2|A0A3B3IRI2_HUMAN,tr|A0A3B3ISY3|A0A3B3ISY3_HUMAN" 7 1123.5641 2.41 13951 13696 2 1123.563653 562.7893 CTP synthase 1 OS=Homo sapiens OX=9606 GN=CTPS1 PE=1 SV=2 5.83 2798.3 - 833253 - - - -0.3889 - 1.262 0.393 - 215.3 1 2 0 -0.0004 10 0 0 0 6.11E+07 2.53E+07 - - - 2.5931 0.8251 221125_WJC_METTL3_EV_vs_WT_F02.13701.13701.2 2.46 12-Jul R.SILC[160.03]C[160.03]LR.K "sp|Q15185|TEBP_HUMAN,tr|A0A087WYT3|A0A087WYT3_HUMAN" 2 920.4572 0.6 13954 13701 2 920.454925 461.2359 Prostaglandin E synthase 3 OS=Homo sapiens OX=9606 GN=PTGES3 PE=1 SV=1 7.8 2798.9 - 1.44E+06 - - - -2.464 - 1.059 0.022 - 187.2 1 2 0 -0.0023 7 0 0 0 5.65E+07 9.35E+07 - - - -0.6156 0.9999 221125_WJC_METTL3_EV_vs_WT_F02.13702.13702.2 8.48E-08 20-Dec K.APDDLVAPVVK.K sp|O43172|PRP4_HUMAN 1 1122.6285 2.14 13955 13702 2 1122.627817 562.3215 U4\U6 small nuclear ribonucleoprotein Prp4 OS=Homo sapiens OX=9606 GN=PRPF4 PE=1 SV=2 4.21 2799 - 1.66E+06 - - - -0.5861 - 2.224 0.577 - 443.2 1 2 0 -0.0007 11 0 0 0 3.78E+08 1.76E+08 - - - 5.4648 0.9889 221125_WJC_METTL3_EV_vs_WT_F02.13703.13703.2 2.29 12-Aug K.NLLAQIK[136.11].S sp|Q92830|KAT2A_HUMAN 1 806.5105 1.15 13956 13703 2 806.51044 404.2625 Histone acetyltransferase KAT2A OS=Homo sapiens OX=9606 GN=KAT2A PE=1 SV=3 8.75 2799.1 - 1.37E+06 - - - -0.1228 - 1.208 0.122 - 171.6 1 2 0 -0.0001 7 0 0 0 2.63E+07 2.29E+07 - - - 0.5408 0.9722 221125_WJC_METTL3_EV_vs_WT_F02.13704.13704.2 0.887 20-Aug K.ASILGAASIGK[136.11].G "sp|Q8NEL9|DDHD1_HUMAN,tr|A0A6E1W401|A0A6E1W401_HUMAN,tr|A0A087X0H7|A0A087X0H7_HUMAN,tr|A0A669KAW5|A0A669KAW5_HUMAN,tr|A0A669KB51|A0A669KB51_HUMAN" 5 994.5902 4.33 13957 13704 2 994.588823 498.3024 Phospholipase DDHD1 OS=Homo sapiens OX=9606 GN=DDHD1 PE=1 SV=2 8.8 2799.2 - 890110 - - - -1.4307 - 1.446 0.058 - 99.8 4 2 0 -0.0014 11 0 0 0 5.85E+07 1.35E+07 - - - 0.1977 0.9999 221125_WJC_METTL3_EV_vs_WT_F02.13705.13705.2 6.93E-07 20-Nov R.YALYDATYETK.E "sp|P23528|COF1_HUMAN,sp|Q9Y281|COF2_HUMAN,tr|E9PP50|E9PP50_HUMAN,tr|G3V1A4|G3V1A4_HUMAN,tr|E9PQB7|E9PQB7_HUMAN,tr|E9PK25|E9PK25_HUMAN,tr|E9PLJ3|E9PLJ3_HUMAN" 7 1336.6187 1.4 13958 13705 2 1336.620315 669.3166 Cofilin-1 OS=Homo sapiens OX=9606 GN=CFL1 PE=1 SV=3 4.37 2799.3 - 642582 - - - 1.2098 - 2.188 0.587 - 348.6 1 2 0 0.0016 11 0 0 0 2.43E+08 1.74E+08 - - - 5.4942 0.9997 221125_WJC_METTL3_EV_vs_WT_F02.13706.13706.2 0.00423 20-Nov R.YALYDATYETK[136.11].E "sp|P23528|COF1_HUMAN,sp|Q9Y281|COF2_HUMAN,tr|E9PP50|E9PP50_HUMAN,tr|G3V1A4|G3V1A4_HUMAN,tr|E9PQB7|E9PQB7_HUMAN,tr|E9PK25|E9PK25_HUMAN,tr|E9PLJ3|E9PLJ3_HUMAN" 7 1344.6329 1.4 13959 13706 2 1344.632469 673.3237 Cofilin-1 OS=Homo sapiens OX=9606 GN=CFL1 PE=1 SV=3 4.37 2799.4 - 628600 - - - -0.319 - 2.041 0.345 - 341.3 1 2 0 -0.0004 11 0 0 0 2.43E+08 1.74E+08 - - - 3.5191 1 221125_WJC_METTL3_EV_vs_WT_F02.13707.13707.2 2.83E-06 15/24 K.ILDSVGIEADDDR.L sp|P05387|RLA2_HUMAN 1 1416.6733 2.55 13960 13707 2 1416.671886 709.3439 60S acidic ribosomal protein P2 OS=Homo sapiens OX=9606 GN=RPLP2 PE=1 SV=1 3.71 2799.6 - 593082 - - - -0.9649 - 2.894 0.602 - 859.1 1 2 0 -0.0014 13 0 0 0 1.62E+07 6.37E+06 - - - 6.2142 0.9997 221125_WJC_METTL3_EV_vs_WT_F02.13709.13709.2 0.0221 14-Aug K.ALEAVFGK[136.11].Y "sp|P38159|RBMX_HUMAN,tr|H3BT71|H3BT71_HUMAN,tr|H0Y6E7|H0Y6E7_HUMAN,tr|H3BR27|H3BR27_HUMAN,tr|H3BNC1|H3BNC1_HUMAN" 5 841.4789 1.48 13961 13709 2 841.478203 421.7467 "RNA-binding motif protein, X chromosome OS=Homo sapiens OX=9606 GN=RBMX PE=1 SV=3" 6.05 2799.8 - 6.95E+07 - - - -0.8331 - 1.613 0.448 - 248 1 2 0 -0.0007 8 0 0 0 2.24E+09 1.52E+09 - - - 3.7916 0.9981 221125_WJC_METTL3_EV_vs_WT_F02.13711.13711.2 0.0706 14-Sep R.MNYFQVAK.T "sp|Q93009|UBP7_HUMAN,tr|A0A669KBL1|A0A669KBL1_HUMAN,tr|H3BND8|H3BND8_HUMAN" 3 999.4848 1.03 13962 13711 2 999.484628 500.7497 Ubiquitin carboxyl-terminal hydrolase 7 OS=Homo sapiens OX=9606 GN=USP7 PE=1 SV=2 8.34 2800 - 1.58E+06 - - - -0.1601 - 1.203 0.299 - 269.8 1 2 0 -0.0002 8 0 0 0 3.78E+07 3.67E+07 - - - 1.8068 0.961 221125_WJC_METTL3_EV_vs_WT_F02.13712.13712.2 0.0636 14-Aug R.FAQLALER[166.11].V "sp|O95071|UBR5_HUMAN,tr|E7EMW7|E7EMW7_HUMAN" 2 956.5319 0.74 13963 13712 2 956.53495 479.2732 E3 ubiquitin-protein ligase UBR5 OS=Homo sapiens OX=9606 GN=UBR5 PE=1 SV=2 6 2800 - 1.46E+06 - - - 3.2032 - 1.508 0.072 - 196.1 1 2 0 0.0031 8 0 0 0 2.91E+07 3.93E+07 - - - 0.8107 0.9996 221125_WJC_METTL3_EV_vs_WT_F02.13713.13713.2 0.161 14-Sep R.FGNAFLNR.F "sp|Q9H223|EHD4_HUMAN,sp|Q9NZN3|EHD3_HUMAN,sp|Q9H4M9|EHD1_HUMAN,tr|C9JC03|C9JC03_HUMAN,tr|C9JIJ3|C9JIJ3_HUMAN,tr|C9IZH1|C9IZH1_HUMAN,tr|A0A024R571|A0A024R571_HUMAN" 7 937.477 0.18 13964 13713 2 937.476786 469.7458 EH domain-containing protein 4 OS=Homo sapiens OX=9606 GN=EHD4 PE=1 SV=1 9.75 2800.1 - 1.47E+06 - - - -0.2283 - 1.739 0.347 - 216.6 1 2 0 -0.0002 8 0 0 0 1.23E+08 6.78E+08 - - - 3.2726 0.9986 221125_WJC_METTL3_EV_vs_WT_F02.13714.13714.2 0.0119 14-Jul R.MLFPEAQR.L sp|Q8WVM0|TFB1M_HUMAN 1 990.4957 1.19 13965 13714 2 990.495636 496.2551 "Dimethyladenosine transferase 1, mitochondrial OS=Homo sapiens OX=9606 GN=TFB1M PE=1 SV=1" 5.75 2800.2 - 795415 - - - -0.0515 - 1.403 0.272 - 154.1 1 2 0 -0.0001 8 0 0 0 2.28E+07 1.92E+07 - - - 2.0712 0.9679 221125_WJC_METTL3_EV_vs_WT_F02.13721.13721.2 0.000586 16-Aug G.YYGYTGAFR.C "sp|P02787|TRFE_HUMAN,sp|P02788|TRFL_HUMAN,tr|H7C5E8|H7C5E8_HUMAN,tr|E7EQB2|E7EQB2_HUMAN,tr|E7ER44|E7ER44_HUMAN" 5 1096.4978 1.71 13970 13721 2 1096.496968 549.2562 Serotransferrin OS=Homo sapiens OX=9606 GN=TF PE=1 SV=3 8.5 2801.1 - 1.92E+06 - - - -0.7542 - 1.294 0.437 - 154.2 1 1 0 -0.0008 9 0 0 0 1.07E+08 6.25E+07 - - - 3.0141 0.9985 221125_WJC_METTL3_EV_vs_WT_F02.13722.13722.2 0.221 18-Oct K.GALVLGSSLK.Q "sp|P46976|GLYG_HUMAN,tr|G5E9W8|G5E9W8_HUMAN,tr|C9JQ42|C9JQ42_HUMAN" 3 943.5702 0.87 13971 13722 2 943.56998 472.7924 Glycogenin-1 OS=Homo sapiens OX=9606 GN=GYG1 PE=1 SV=4 8.75 2801.2 - 1.14E+06 - - - -0.2671 - 1.701 0.205 - 234.7 1 2 0 -0.0003 10 0 0 0 3.39E+07 3.91E+07 - - - 2.0378 0.9962 221125_WJC_METTL3_EV_vs_WT_F02.13723.13723.2 1.89 18-Oct K.GALVLGSSLK[136.11].Q "sp|P46976|GLYG_HUMAN,tr|G5E9W8|G5E9W8_HUMAN,tr|C9JQ42|C9JQ42_HUMAN" 3 951.5844 0.87 13972 13723 2 951.584085 476.7995 Glycogenin-1 OS=Homo sapiens OX=9606 GN=GYG1 PE=1 SV=4 8.75 2801.3 - 2.06E+06 - - - -0.3647 - 1.738 0.097 - 283 1 2 0 -0.0003 10 0 0 0 3.40E+07 3.91E+07 - - - 1.3002 0.9235 221125_WJC_METTL3_EV_vs_WT_F02.13724.13724.2 3.59 14-May R.ELDIMEPK[136.11].V sp|Q13200|PSMD2_HUMAN 1 981.4932 0.6 13973 13724 2 981.492688 491.7539 26S proteasome non-ATPase regulatory subunit 2 OS=Homo sapiens OX=9606 GN=PSMD2 PE=1 SV=3 4.14 2801.3 - 3.42E+06 - - - -0.5563 - 1.04 0.02 - 68.4 1 2 0 -0.0005 8 0 0 0 2.38E+07 3.93E+07 - - - -0.6932 0.9975 221125_WJC_METTL3_EV_vs_WT_F02.13725.13725.2 0.155 12-Jul K.AWLMSDK[136.11].T "sp|P33908|MA1A1_HUMAN,sp|O60476|MA1A2_HUMAN,tr|H0Y7H1|H0Y7H1_HUMAN" 3 857.4197 1.36 13974 13725 2 857.419331 429.7171 "Mannosyl-oligosaccharide 1,2-alpha-mannosidase IA OS=Homo sapiens OX=9606 GN=MAN1A1 PE=1 SV=3" 5.88 2801.4 - 607105 - - - -0.4012 - 1.292 0.241 - 207 1 2 0 -0.0003 7 0 0 0 2.77E+07 2.05E+07 - - - 1.6327 0.9998 221125_WJC_METTL3_EV_vs_WT_F02.13729.13729.2 0.00277 14-Nov K.TTLVIMER[166.11].L "sp|Q14974|IMB1_HUMAN,tr|J3QKQ5|J3QKQ5_HUMAN,tr|J3KTM9|J3KTM9_HUMAN" 3 971.5349 1.17 13977 13729 2 971.53512 486.7747 Importin subunit beta-1 OS=Homo sapiens OX=9606 GN=KPNB1 PE=1 SV=2 5.66 2801.9 - 8.86E+06 - - - 0.2028 - 2.018 0.399 - 677.8 1 2 0 0.0002 8 0 0 0 2.08E+08 1.78E+08 - - - 4.1055 0.9886 221125_WJC_METTL3_EV_vs_WT_F02.13731.13731.2 6.28 12-Jul K.VENLALK.N sp|Q15545|TAF7_HUMAN 1 785.4647 1.82 13978 13731 2 785.464696 393.7396 Transcription initiation factor TFIID subunit 7 OS=Homo sapiens OX=9606 GN=TAF7 PE=1 SV=1 5.97 2802.1 - 6.56E+06 - - - -0.0102 - 1.254 0.104 - 162.2 1 2 0 0 7 0 0 0 2.86E+08 1.57E+08 - - - 0.5263 0.9854 221125_WJC_METTL3_EV_vs_WT_F02.13732.13732.2 1.28 12-Jul K.TELLGLK.E sp|Q69YU5|BWNIN_HUMAN 1 772.4695 1.65 13979 13732 2 772.469426 387.242 Protein BRAWNIN OS=Homo sapiens OX=9606 GN=BRAWNIN PE=1 SV=2 5.66 2802.2 - 2.40E+06 - - - -0.0375 - 1.139 0.123 - 200.6 1 2 0 0 7 0 0 0 6.57E+07 3.99E+07 - - - 0.3619 0.9954 221125_WJC_METTL3_EV_vs_WT_F02.13734.13734.2 0.0469 12-Jun K.SFTVDIR[166.11].A "sp|Q00341|VIGLN_HUMAN,tr|A0A024R4E5|A0A024R4E5_HUMAN,tr|H7BZC3|H7BZC3_HUMAN,tr|H7C2D1|H7C2D1_HUMAN,tr|H0Y394|H0Y394_HUMAN" 5 846.4475 0.78 13981 13734 2 846.446717 424.231 Vigilin OS=Homo sapiens OX=9606 GN=HDLBP PE=1 SV=2 5.55 2802.3 - 2.82E+06 - - - -0.9109 - 1.293 0.19 - 177 1 2 0 -0.0008 7 0 0 0 7.89E+07 1.02E+08 - - - 1.2583 0.9995 221125_WJC_METTL3_EV_vs_WT_F02.13735.13735.2 0.000337 18-Jul R.LVPGPVFGSK[136.11].D "sp|Q12907|LMAN2_HUMAN,tr|D6RBV2|D6RBV2_HUMAN,tr|D6RBH1|D6RBH1_HUMAN,tr|D6RIU4|D6RIU4_HUMAN" 4 1007.5895 2.74 13982 13735 2 1007.589031 504.802 Vesicular integral-membrane protein VIP36 OS=Homo sapiens OX=9606 GN=LMAN2 PE=1 SV=1 8.75 2802.3 - 1.86E+06 - - - -0.4823 - 1.434 0.399 - 153.1 1 2 0 -0.0005 10 0 0 0 2.63E+08 9.57E+07 - - - 2.994 0.9996 221125_WJC_METTL3_EV_vs_WT_F02.13737.13737.2 0.000569 22-Dec K.ILLNAGAEINSR[166.11].T "sp|O75179|ANR17_HUMAN,sp|Q8IWZ3|ANKH1_HUMAN,tr|E9PDP5|E9PDP5_HUMAN,tr|H0YM23|H0YM23_HUMAN,tr|H3BLS9|H3BLS9_HUMAN,tr|H0YLQ3|H0YLQ3_HUMAN,tr|H7C2F5|H7C2F5_HUMAN" 7 1279.7124 1.52 13984 13737 2 1279.715404 640.8635 Ankyrin repeat domain-containing protein 17 OS=Homo sapiens OX=9606 GN=ANKRD17 PE=1 SV=3 6 2802.5 - 588198 - - - 2.3708 - 2.244 0.471 - 517.5 1 2 0 0.003 12 0 0 0 7.79E+07 5.11E+07 - - - 4.6455 0.9974 221125_WJC_METTL3_EV_vs_WT_F02.13738.13738.2 0.0769 24-Jul R.LQSAMTEGGVVLR[166.11].E sp|Q9H0U6|RM18_HUMAN 1 1369.7263 1.48 13985 13738 2 1369.724888 685.8704 "39S ribosomal protein L18, mitochondrial OS=Homo sapiens OX=9606 GN=MRPL18 PE=1 SV=1" 6 2802.7 - 177224 - - - -1.0345 - 1.564 0.227 - 67.4 2 2 0 -0.0014 13 0 0 0 1.11E+07 7.49E+06 - - - 1.7306 0.9986 221125_WJC_METTL3_EV_vs_WT_F02.13742.13742.2 0.0036 14-Jul K.EMWTEVPK.S "sp|P62316|SMD2_HUMAN,tr|K7EJB5|K7EJB5_HUMAN" 2 1018.4794 1.24 13987 13742 2 1018.477962 510.247 Small nuclear ribonucleoprotein Sm D2 OS=Homo sapiens OX=9606 GN=SNRPD2 PE=1 SV=1 4.53 2803.1 - 5.24E+06 - - - -1.3805 - 1.421 0.308 - 205.9 1 2 0 -0.0014 8 0 0 0 1.56E+08 1.26E+08 - - - 2.3751 0.9994 221125_WJC_METTL3_EV_vs_WT_F02.13743.13743.2 0.0137 14-Aug K.GQFETYLR.D "sp|Q13510|ASAH1_HUMAN,tr|A0A1B0GV06|A0A1B0GV06_HUMAN,tr|A0A1B0GUE3|A0A1B0GUE3_HUMAN,tr|A0A1B0GUH5|A0A1B0GUH5_HUMAN,tr|A0A1B0GUA4|A0A1B0GUA4_HUMAN,tr|A0A1B0GTM3|A0A1B0GTM3_HUMAN,tr|A0A1B0GW68|A0A1B0GW68_HUMAN,tr|A0A1B0GTZ5|A0A1B0GTZ5_HUMAN,tr|A0A1B0GUW4|A0A1B0GUW4_HUMAN,tr|E7EMM4|E7EMM4_HUMAN,tr|A0A1B0GTP7|A0A1B0GTP7_HUMAN,tr|A0A1B0GUG1|A0A1B0GUG1_HUMAN" 12 1012.4978 158.81 13988 13743 2 1012.497199 507.2562 Acid ceramidase OS=Homo sapiens OX=9606 GN=ASAH1 PE=1 SV=5 6 2803.1 - 2.04E+06 - - - -0.5886 - 1.694 0.313 - 340.9 1 2 0 -0.0006 8 0 0 0 3.77E+07 2.37E+05 - - - 2.9423 0.9999 221125_WJC_METTL3_EV_vs_WT_F02.13745.13745.2 1.08E-06 13/22 K.ILLNAGAEINSR.T "sp|O75179|ANR17_HUMAN,sp|Q8IWZ3|ANKH1_HUMAN,tr|E9PDP5|E9PDP5_HUMAN,tr|H0YM23|H0YM23_HUMAN,tr|H3BLS9|H3BLS9_HUMAN,tr|H0YLQ3|H0YLQ3_HUMAN,tr|H7C2F5|H7C2F5_HUMAN" 7 1269.7041 1.51 13990 13745 2 1269.705388 635.8593 Ankyrin repeat domain-containing protein 17 OS=Homo sapiens OX=9606 GN=ANKRD17 PE=1 SV=3 6 2803.4 - 1.03E+06 - - - 1.0144 - 2.544 0.541 - 676.9 1 2 0 0.0013 12 0 0 0 7.79E+07 5.14E+07 - - - 5.4932 0.9799 221125_WJC_METTL3_EV_vs_WT_F02.13747.13747.2 0.751 14-Jul R.GVSINVLR[166.11].H "sp|Q9Y597|KCTD3_HUMAN,tr|H0Y566|H0Y566_HUMAN" 2 866.5213 0.46 13991 13747 2 866.52064 434.2679 BTB\POZ domain-containing protein KCTD3 OS=Homo sapiens OX=9606 GN=KCTD3 PE=1 SV=2 9.75 2803.6 - 408837 - - - -0.7859 - 1.143 0.123 - 123.5 2 2 0 -0.0007 8 0 0 0 4.07E+06 8.79E+06 - - - 0.2179 0.9982 221125_WJC_METTL3_EV_vs_WT_F02.13749.13749.2 0.108 20-Oct K.VIILGDSGVGK.T "sp|P51149|RAB7A_HUMAN,tr|C9J592|C9J592_HUMAN,tr|C9J4V0|C9J4V0_HUMAN,tr|C9J7D1|C9J7D1_HUMAN,tr|A0A6Q8PH84|A0A6Q8PH84_HUMAN,tr|C9J8S3|C9J8S3_HUMAN,tr|C9IZZ0|C9IZZ0_HUMAN,tr|C9J4S4|C9J4S4_HUMAN,tr|A0A6Q8PG52|A0A6Q8PG52_HUMAN" 9 1056.6179 1.09 13992 13749 2 1056.620497 529.3162 Ras-related protein Rab-7a OS=Homo sapiens OX=9606 GN=RAB7A PE=1 SV=1 5.81 2803.8 - 2.38E+06 - - - 2.4484 - 1.697 0.329 - 294.4 1 2 0 0.0026 11 0 0 0 4.78E+08 4.37E+08 - - - 2.9009 0.9892 221125_WJC_METTL3_EV_vs_WT_F02.13750.13750.2 0.199 14-Jul K.ELEEEWVK[136.11].L sp|Q14008|CKAP5_HUMAN 1 1068.5219 1.39 13993 13750 2 1068.519508 535.2682 Cytoskeleton-associated protein 5 OS=Homo sapiens OX=9606 GN=CKAP5 PE=1 SV=3 4.09 2803.9 - 923620 - - - -2.2302 - 1.264 0.199 - 152 1 2 0 -0.0024 8 0 0 0 2.52E+07 1.81E+07 - - - 1.2166 0.9998 221125_WJC_METTL3_EV_vs_WT_F02.13753.13753.2 0.00133 24-Oct R.LQSAMTEGGVVLR.E sp|Q9H0U6|RM18_HUMAN 1 1359.718 1.48 13996 13753 2 1359.716648 680.8663 "39S ribosomal protein L18, mitochondrial OS=Homo sapiens OX=9606 GN=MRPL18 PE=1 SV=1" 6 2804.1 - 297781 - - - -1.0201 - 2.314 0.443 - 302.8 1 2 0 -0.0014 13 0 0 0 1.11E+07 7.49E+06 - - - 4.4658 0.9781 221125_WJC_METTL3_EV_vs_WT_F02.13758.13758.2 5.13 12-Jul K.VENLALK[136.11].N sp|Q15545|TAF7_HUMAN 1 793.4789 1.82 13999 13758 2 793.47884 397.7467 Transcription initiation factor TFIID subunit 7 OS=Homo sapiens OX=9606 GN=TAF7 PE=1 SV=1 5.97 2804.7 - 6.65E+06 - - - -0.0807 - 1.193 0.067 - 159.2 1 2 0 -0.0001 7 0 0 0 2.85E+08 1.56E+08 - - - 0.095 0.9494 221125_WJC_METTL3_EV_vs_WT_F02.13759.13759.2 0.921 14-Jun R.ELLTLDEK[136.11].D "sp|P46781|RS9_HUMAN,tr|C9JM19|C9JM19_HUMAN,tr|B5MCT8|B5MCT8_HUMAN,tr|F2Z3C0|F2Z3C0_HUMAN,tr|A8MXK4|A8MXK4_HUMAN" 5 967.5317 5.76 14000 13759 2 967.535022 484.7731 40S ribosomal protein S9 OS=Homo sapiens OX=9606 GN=RPS9 PE=1 SV=3 4.14 2804.8 - 1.30E+06 - - - 3.4045 - 1.473 0.088 - 117.6 2 2 0 0.0033 8 0 0 0 2.07E+08 3.60E+07 - - - 0.7235 0.8363 221125_WJC_METTL3_EV_vs_WT_F02.13760.13760.2 0.0857 16-Jul L.EDAVALYKK.L sp|Q9NX57|RAB20_HUMAN 1 1035.5601 4.94 14001 13760 2 1035.559623 518.7873 Ras-related protein Rab-20 OS=Homo sapiens OX=9606 GN=RAB20 PE=1 SV=1 6.17 2804.9 - 842325 - - - -0.423 - 1.253 0.235 - 111.2 1 1 0 -0.0004 9 0 0 0 2.26E+07 4.57E+06 - - - 1.4291 0.9997 221125_WJC_METTL3_EV_vs_WT_F02.13761.13761.2 6.12E-07 22-Nov K.LLEESNMELEER[166.11].R "sp|Q9Y496|KIF3A_HUMAN,tr|A0A087X011|A0A087X011_HUMAN,tr|H7C2F6|H7C2F6_HUMAN,tr|J3KPF9|J3KPF9_HUMAN,tr|E9PES4|E9PES4_HUMAN" 5 1500.7005 0.57 14002 13761 2 1500.703849 751.3575 Kinesin-like protein KIF3A OS=Homo sapiens OX=9606 GN=KIF3A PE=1 SV=4 3.98 2805 - 195409 - - - 2.2023 - 2.286 0.555 - 495.2 1 2 0 0.0033 12 0 0 0 1.79E+06 3.16E+06 - - - 5.3147 0.7971 221125_WJC_METTL3_EV_vs_WT_F02.13766.13766.2 0.529 14-Aug N.TVLSTPFR.T sp|Q99459|CDC5L_HUMAN 1 919.5127 1.08 14005 13766 2 919.512856 460.7636 Cell division cycle 5-like protein OS=Homo sapiens OX=9606 GN=CDC5L PE=1 SV=2 9.41 2805.5 - 1.62E+06 - - - 0.1512 - 1.338 0.178 - 174.2 1 1 0 0.0001 8 0 0 0 5.05E+07 4.65E+07 - - - 1.2338 0.9976 221125_WJC_METTL3_EV_vs_WT_F02.13767.13767.2 0.000496 20-Nov K.EVTPEGLQMVK[136.11].K "sp|P22234|PUR6_HUMAN,tr|D6RF62|D6RF62_HUMAN,tr|E9PBS1|E9PBS1_HUMAN" 3 1237.6468 0.7 14006 13767 2 1237.652397 619.8307 Multifunctional protein ADE2 OS=Homo sapiens OX=9606 GN=PAICS PE=1 SV=3 4.53 2805.7 - 949158 - - - 4.5433 - 1.994 0.464 - 394 1 2 0 0.0056 11 0 0 0 5.57E+07 7.93E+07 - - - 4.3333 0.9996 221125_WJC_METTL3_EV_vs_WT_F02.13774.13774.2 1.15 16-Aug R.LLQLQEQMR.A sp|P15924|DESP_HUMAN 1 1157.6227 16.77 14011 13774 2 1157.622899 579.8186 Desmoplakin OS=Homo sapiens OX=9606 GN=DSP PE=1 SV=3 6 2806.5 - 8.99E+06 - - - 0.1909 - 1.941 0.332 - 276.5 1 2 0 0.0002 9 0 0 0 3.03E+08 1.81E+07 - - - 3.4118 0.9918 221125_WJC_METTL3_EV_vs_WT_F02.13775.13775.2 2.81 12-Jun K.WGVPIEK.L "sp|P11387|TOP1_HUMAN,tr|A0A7P0T852|A0A7P0T852_HUMAN" 2 827.4541 0.17 14012 13775 2 827.454191 414.7343 DNA topoisomerase 1 OS=Homo sapiens OX=9606 GN=TOP1 PE=1 SV=2 6 2806.6 - 1.42E+06 - - - 0.0628 - 1.304 0.136 - 105 2 2 0 0.0001 7 0 0 0 5.09E+07 3.05E+08 - - - 0.7521 0.9853 221125_WJC_METTL3_EV_vs_WT_F02.13776.13776.2 0.00387 18-Oct N.GILNVSAVDK[136.11].S "sp|P11142|HSP7C_HUMAN,tr|E9PNE6|E9PNE6_HUMAN,tr|A8K7Q2|A8K7Q2_HUMAN,tr|E9PKE3|E9PKE3_HUMAN,tr|E9PM13|E9PM13_HUMAN,tr|E9PS65|E9PS65_HUMAN" 6 1022.5852 0.2 14013 13776 2 1022.585224 512.2999 Heat shock cognate 71 kDa protein OS=Homo sapiens OX=9606 GN=HSPA8 PE=1 SV=1 5.84 2806.6 - 6.25E+06 - - - 0.0626 - 1.987 0.386 - 265.2 1 1 0 0.0001 10 0 0 0 7.74E+07 3.96E+08 - - - 3.8086 0.9601 221125_WJC_METTL3_EV_vs_WT_F02.13780.13780.2 0.459 20-Nov K.EALIAASETLK[136.11].E "sp|Q9NTJ3|SMC4_HUMAN,tr|E9PD53|E9PD53_HUMAN" 2 1152.6482 0.85 14015 13780 2 1152.650939 577.3314 Structural maintenance of chromosomes protein 4 OS=Homo sapiens OX=9606 GN=SMC4 PE=1 SV=2 4.53 2807.1 - 5.25E+06 - - - 2.4162 - 1.434 0.055 - 244.4 1 2 0 0.0028 11 0 0 0 2.21E+08 2.62E+08 - - - 0.4215 0.9992 221125_WJC_METTL3_EV_vs_WT_F02.13781.13781.2 0.00595 14-Jul K.GNEILELK.C sp|P12270|TPR_HUMAN 1 914.5073 1.21 14016 13781 2 914.507344 458.2609 Nucleoprotein TPR OS=Homo sapiens OX=9606 GN=TPR PE=1 SV=3 4.53 2807.2 - 1.81E+06 - - - 0.0514 - 1.605 0.288 - 231.2 1 2 0 0 8 0 0 0 5.14E+07 4.25E+07 - - - 2.5951 0.9766 221125_WJC_METTL3_EV_vs_WT_F02.13788.13788.2 0.82 12-Jun R.ITDFQFK.E "sp|Q70IA6|MOB2_HUMAN,tr|A0A087WVS8|A0A087WVS8_HUMAN" 2 897.4596 3.13 14021 13788 2 897.458538 449.7371 MOB kinase activator 2 OS=Homo sapiens OX=9606 GN=MOB2 PE=1 SV=1 5.84 2808.1 - 831140 - - - -1.2045 - 1.29 0.052 - 77.9 1 2 0 -0.0011 7 0 0 0 4.42E+08 1.41E+08 - - - 0.2316 0.9948 221125_WJC_METTL3_EV_vs_WT_F02.13795.13795.2 0.599 14-Jul K.LQLVQGIR.- "sp|Q86TB9|PATL1_HUMAN,tr|F8W1G6|F8W1G6_HUMAN" 2 925.5709 0.91 14026 13795 2 925.571507 463.7927 Protein PAT1 homolog 1 OS=Homo sapiens OX=9606 GN=PATL1 PE=1 SV=2 9.75 2808.9 - 1.55E+06 - - - 0.6547 - 1.535 0.114 - 142.9 1 2 0 0.0006 8 0 0 0 3.30E+07 3.61E+07 - - - 1.1752 0.9961 221125_WJC_METTL3_EV_vs_WT_F02.13798.13798.2 0.129 14-Jun K.ETVLSALK.E "sp|Q96HA1|P121A_HUMAN,sp|A8CG34|P121C_HUMAN,sp|Q6PJE2|POZP3_HUMAN,tr|A0A0J9YWR1|A0A0J9YWR1_HUMAN,tr|C9J370|C9J370_HUMAN,tr|C9JER0|C9JER0_HUMAN" 6 859.5015 2.22 14028 13798 2 859.501047 430.758 Nuclear envelope pore membrane protein POM 121 OS=Homo sapiens OX=9606 GN=POM121 PE=1 SV=2 6.1 2809.2 - 2.40E+06 - - - -0.5084 - 1.363 0.179 - 146.7 1 2 0 -0.0004 8 0 0 0 2.22E+08 1.00E+08 - - - 1.297 0.8585 221125_WJC_METTL3_EV_vs_WT_F02.13800.13800.2 0.677 14-Aug D.IADIEALK[136.11].E "sp|Q70CQ2|UBP34_HUMAN,sp|O75792|RNH2A_HUMAN,tr|A0A2R8Y606|A0A2R8Y606_HUMAN,tr|A0A2R8Y658|A0A2R8Y658_HUMAN" 4 879.5157 1.63 14029 13800 2 879.516284 440.7651 Ubiquitin carboxyl-terminal hydrolase 34 OS=Homo sapiens OX=9606 GN=USP34 PE=1 SV=2 4.37 2809.4 - 2.61E+06 - - - 0.6822 - 1.655 0.149 - 140.4 1 1 0 0.0006 8 0 0 0 1.61E+08 9.88E+07 - - - 1.6608 0.9996 221125_WJC_METTL3_EV_vs_WT_F02.13801.13801.2 0.00135 12-Aug K.TC[160.03]TFILR[166.11].G sp|Q99832|TCPH_HUMAN 1 919.4825 0.19 14030 13801 2 919.481009 460.7485 T-complex protein 1 subunit eta OS=Homo sapiens OX=9606 GN=CCT7 PE=1 SV=2 7.91 2809.5 - 2.23E+06 - - - -1.614 - 1.606 0.436 - 290.1 1 2 0 -0.0015 7 0 0 0 1.32E+08 7.04E+08 - - - 3.7619 0.9991 221125_WJC_METTL3_EV_vs_WT_F02.13805.13805.2 0.543 16-Oct R.LLQLQEQMR[166.11].A sp|P15924|DESP_HUMAN 1 1167.6309 23.24 14032 13805 2 1167.631627 584.8228 Desmoplakin OS=Homo sapiens OX=9606 GN=DSP PE=1 SV=3 6 2810 - 635126 - - - 0.5815 - 1.911 0.218 - 358.8 1 2 0 0.0007 9 0 0 0 2.96E+08 1.28E+07 - - - 2.5246 1 221125_WJC_METTL3_EV_vs_WT_F02.13808.13808.2 2.54E-07 Oct-32 K.IISNASC[160.03]TTNC[160.03]LAPLAK[136.11].V "sp|P04406|G3P_HUMAN,tr|E7EUT5|E7EUT5_HUMAN" 2 1840.9267 1.41 14035 13808 2 1840.925499 921.4706 Glyceraldehyde-3-phosphate dehydrogenase OS=Homo sapiens OX=9606 GN=GAPDH PE=1 SV=3 8.06 2810.4 - 140036 - - - -0.6279 - 2.349 0.654 - 174.4 1 2 0 -0.0012 17 0 0 0 5.45E+06 3.86E+06 - - - 5.9707 0.9998 221125_WJC_METTL3_EV_vs_WT_F02.13811.13811.2 0.00106 20-Nov K.GPLLEEQALTK[136.11].A sp|Q52LJ0|FA98B_HUMAN 1 1205.6747 1.25 14036 13811 2 1205.676486 603.8446 Protein FAM98B OS=Homo sapiens OX=9606 GN=FAM98B PE=1 SV=2 4.53 2810.8 - 3.81E+06 - - - 1.478 - 2.18 0.485 - 380.4 1 2 0 0.0018 11 0 0 0 1.57E+08 1.26E+08 - - - 4.7309 0.9717 221125_WJC_METTL3_EV_vs_WT_F02.13814.13814.2 5.25 14-Jul K.LQLVQGIR[166.11].- "sp|Q86TB9|PATL1_HUMAN,tr|F8W1G6|F8W1G6_HUMAN" 2 935.5792 0.94 14039 13814 2 935.580471 468.7969 Protein PAT1 homolog 1 OS=Homo sapiens OX=9606 GN=PATL1 PE=1 SV=2 9.75 2811 - 1.41E+06 - - - 1.3895 - 1.568 0.033 - 143.2 8 2 0 0.0013 8 0 0 0 3.33E+07 3.53E+07 - - - 0.2375 0.9995 221125_WJC_METTL3_EV_vs_WT_F02.13815.13815.2 0.000906 20-Dec K.GALALAQAVQR.A "sp|P11586|C1TC_HUMAN,tr|F5H2F4|F5H2F4_HUMAN,tr|V9GZ78|V9GZ78_HUMAN,tr|V9GYY3|V9GYY3_HUMAN,tr|A0A494C1T2|A0A494C1T2_HUMAN" 5 1096.6353 1.72 14040 13815 2 1096.63758 549.3249 "C-1-tetrahydrofolate synthase, cytoplasmic OS=Homo sapiens OX=9606 GN=MTHFD1 PE=1 SV=4" 9.75 2811.1 - 1.02E+06 - - - 2.0864 - 2.25 0.387 - 500.6 1 2 0 0.0023 11 0 0 0 6.58E+07 3.82E+07 - - - 4.0924 0.9979 221125_WJC_METTL3_EV_vs_WT_F02.13819.13819.2 0.0159 14-Aug R.TIEALMDR[166.11].G sp|P82932|RT06_HUMAN 1 957.4829 1.15 14043 13819 2 957.483843 479.7487 "28S ribosomal protein S6, mitochondrial OS=Homo sapiens OX=9606 GN=MRPS6 PE=1 SV=3" 4.37 2811.5 - 2.15E+06 - - - 0.9985 - 1.251 0.307 - 205.6 1 2 0 0.001 8 0 0 0 9.98E+07 8.65E+07 - - - 1.9836 0.9996 221125_WJC_METTL3_EV_vs_WT_F02.13822.13822.3 5.34E-05 Oct-36 R.LVNHFVEEFK[136.11].R "sp|P0DMV8|HS71A_HUMAN,sp|P0DMV9|HS71B_HUMAN,tr|V9GZ37|V9GZ37_HUMAN,tr|A0A0G2JIW1|A0A0G2JIW1_HUMAN" 4 1268.6645 0.77 14045 13822 3 1268.663886 423.8954 Heat shock 70 kDa protein 1A OS=Homo sapiens OX=9606 GN=HSPA1A PE=1 SV=1 5.4 2811.8 - 1.76E+06 - - - -0.4627 - 2.111 0.291 - 134.2 1 2 0 -0.0006 10 0 0 0 3.53E+07 4.58E+07 - - - 3.9662 0.9995 221125_WJC_METTL3_EV_vs_WT_F02.13823.13823.2 0.00256 14-Sep K.FQNALLVR.Y "sp|P02768|ALBU_HUMAN,tr|A0A087WWT3|A0A087WWT3_HUMAN,tr|B7WNR0|B7WNR0_HUMAN,tr|H0YA55|H0YA55_HUMAN,tr|A0A0C4DGB6|A0A0C4DGB6_HUMAN,tr|D6RHD5|D6RHD5_HUMAN,tr|C9JKR2|C9JKR2_HUMAN" 7 959.5553 999 14046 13823 2 959.55491 480.7849 Albumin OS=Homo sapiens OX=9606 GN=ALB PE=1 SV=2 9.75 2811.9 - 2.13E+06 - - - -0.3543 - 1.78 0.293 - 247.6 1 2 0 -0.0003 8 0 0 0 3.01E+08 0.00E+00 - - - 2.944 0.9973 221125_WJC_METTL3_EV_vs_WT_F02.13824.13824.2 0.0537 14-Jul K.QVEELFER.K "sp|P78347|GTF2I_HUMAN,tr|A0A494C1K3|A0A494C1K3_HUMAN" 2 1048.5189 1.5 14047 13824 2 1048.520231 525.2667 General transcription factor II-I OS=Homo sapiens OX=9606 GN=GTF2I PE=1 SV=2 4.25 2812 - 440179 - - - 1.2456 - 1.604 0.189 - 110.6 1 2 0 0.0013 8 0 0 0 1.66E+09 1.10E+09 - - - 1.8616 0.9999 221125_WJC_METTL3_EV_vs_WT_F02.13825.13825.2 4.40E-07 Sep-32 K.IISNASC[160.03]TTNC[160.03]LAPLAK.V "sp|P04406|G3P_HUMAN,tr|E7EUT5|E7EUT5_HUMAN" 2 1832.9125 1.41 14048 13825 2 1832.912032 917.4635 Glyceraldehyde-3-phosphate dehydrogenase OS=Homo sapiens OX=9606 GN=GAPDH PE=1 SV=3 8.06 2812.1 - 211807 - - - -0.2308 - 2.15 0.601 - 146.1 1 2 0 -0.0004 17 0 0 0 5.45E+06 3.86E+06 - - - 5.3618 0.9989 221125_WJC_METTL3_EV_vs_WT_F02.13826.13826.2 0.00802 20-Aug K.LEAAQNVLLC[160.03]K.E "sp|Q9NVC6|MED17_HUMAN,tr|E9PM72|E9PM72_HUMAN,tr|A0A1W2PQE4|A0A1W2PQE4_HUMAN,tr|A0A1W2PQ48|A0A1W2PQ48_HUMAN,tr|A0A1W2PS27|A0A1W2PS27_HUMAN,tr|A0A1W2PRB8|A0A1W2PRB8_HUMAN,tr|A0A1W2PNW7|A0A1W2PNW7_HUMAN,tr|A0A1W2PS69|A0A1W2PS69_HUMAN" 8 1257.6751 1.53 14049 13826 2 1257.675993 629.8448 Mediator of RNA polymerase II transcription subunit 17 OS=Homo sapiens OX=9606 GN=MED17 PE=1 SV=2 5.99 2812.3 - 181008 - - - 0.7037 - 1.723 0.263 - 233.4 1 2 0 0.0009 11 0 0 0 5.24E+06 3.44E+06 - - - 2.4551 0.994 221125_WJC_METTL3_EV_vs_WT_F02.13830.13830.2 0.165 14-Jun R.QMFGQFGK[136.11].L "sp|O43251|RFOX2_HUMAN,sp|Q9NWB1|RFOX1_HUMAN,sp|A6NFN3|RFOX3_HUMAN,tr|A0A6Q8PGE0|A0A6Q8PGE0_HUMAN,tr|A0A6Q8PH77|A0A6Q8PH77_HUMAN,tr|A0A286YEU2|A0A286YEU2_HUMAN,tr|A0A087X2B1|A0A087X2B1_HUMAN,tr|F8VR27|F8VR27_HUMAN,tr|B7Z1U7|B7Z1U7_HUMAN,tr|B0QYV1|B0QYV1_HUMAN,tr|A0A6Q8PHA3|A0A6Q8PHA3_HUMAN,tr|A0A3B3ITL7|A0A3B3ITL7_HUMAN,tr|F8VZY7|F8VZY7_HUMAN,tr|B0QYY4|B0QYY4_HUMAN,tr|J3KNW3|J3KNW3_HUMAN,tr|F8VZG9|F8VZG9_HUMAN,tr|J3QRF4|J3QRF4_HUMAN,tr|A0A6Q8PFM4|A0A6Q8PFM4_HUMAN,tr|S4R469|S4R469_HUMAN,tr|A0A804HKG7|A0A804HKG7_HUMAN,tr|A0A0G2JRA5|A0A0G2JRA5_HUMAN,tr|A0A804HJM2|A0A804HJM2_HUMAN,tr|J3QQZ2|J3QQZ2_HUMAN,tr|I3L1D4|I3L1D4_HUMAN,tr|B0QYY7|B0QYY7_HUMAN,tr|A0A0G2JSB3|A0A0G2JSB3_HUMAN" 26 949.4571 1 14051 13830 2 949.456681 475.7358 RNA binding protein fox-1 homolog 2 OS=Homo sapiens OX=9606 GN=RBFOX2 PE=1 SV=3 8.75 2812.7 - 2.64E+06 - - - -0.4655 - 1.161 0.203 - 136.9 1 2 0 -0.0004 8 0 0 0 1.90E+09 1.90E+09 - - - 0.9904 0.9989 221125_WJC_METTL3_EV_vs_WT_F02.13831.13831.2 0.083 16-Aug R.VAALQNLVK.L "sp|Q14974|IMB1_HUMAN,tr|J3KTM9|J3KTM9_HUMAN" 2 954.5862 1.27 14052 13831 2 954.586718 478.3004 Importin subunit beta-1 OS=Homo sapiens OX=9606 GN=KPNB1 PE=1 SV=2 8.72 2812.8 - 1.56E+06 - - - 0.5259 - 1.606 0.261 - 204.4 1 2 0 0.0005 9 0 0 0 4.51E+08 3.54E+08 - - - 2.3392 0.9998 221125_WJC_METTL3_EV_vs_WT_F02.13834.13834.2 0.229 18-Nov R.ISGLIYEETR[166.11].G sp|P62805|H4_HUMAN 1 1189.6218 1.12 14055 13834 2 1189.622318 595.8182 Histone H4 OS=Homo sapiens OX=9606 GN=H4C1 PE=1 SV=2 4.53 2813.1 - 735840 - - - 0.4161 - 2.61 0.298 - 431.3 1 2 0 0.0005 10 0 0 0 5.40E+09 4.82E+09 - - - 3.9197 0.9995 221125_WJC_METTL3_EV_vs_WT_F02.13839.13839.2 0.00919 18-Sep R.LGLMPPPEPK.V sp|O43395|PRPF3_HUMAN 1 1077.5893 4.33 14058 13839 2 1077.59024 539.8019 U4\U6 small nuclear ribonucleoprotein Prp3 OS=Homo sapiens OX=9606 GN=PRPF3 PE=1 SV=2 6 2813.6 - 1.49E+06 - - - 0.9159 - 1.99 0.304 - 253.7 1 2 0 0.001 10 0 0 0 9.22E+07 2.13E+07 - - - 3.2068 0.9998 221125_WJC_METTL3_EV_vs_WT_F02.13840.13840.2 0.0906 18-Dec R.ISGLIYEETR.G sp|P62805|H4_HUMAN 1 1179.6136 1.12 14059 13840 2 1179.614284 590.8141 Histone H4 OS=Homo sapiens OX=9606 GN=H4C1 PE=1 SV=2 4.53 2813.7 - 1.25E+06 - - - 0.6197 - 2.646 0.388 - 537.2 1 2 0 0.0007 10 0 0 0 5.40E+09 4.82E+09 - - - 4.6226 0.9805 221125_WJC_METTL3_EV_vs_WT_F02.13846.13846.2 0.442 18-Jun R.IEGLTPEEIR[166.11].N sp|O75449|KTNA1_HUMAN 1 1165.6218 20.19 14063 13846 2 1165.623282 583.8182 Katanin p60 ATPase-containing subunit A1 OS=Homo sapiens OX=9606 GN=KATNA1 PE=1 SV=1 4.25 2814.5 - 239933 - - - 1.2517 - 1.29 0.093 - 75 1 2 0 0.0015 10 0 0 0 2.48E+08 1.23E+07 - - - 0.4382 0.999 221125_WJC_METTL3_EV_vs_WT_F02.13852.13852.2 0.000231 22-Aug K.IGDGMNAYVAYK.V sp|Q13596|SNX1_HUMAN 1 1300.6122 1.81 14067 13852 2 1300.608357 651.3134 Sorting nexin-1 OS=Homo sapiens OX=9606 GN=SNX1 PE=1 SV=3 5.83 2815.2 - 215445 - - - -2.934 - 1.682 0.465 - 73.2 1 2 0 -0.0038 12 0 0 0 1.09E+07 6.04E+06 - - - 3.8425 0.9995 221125_WJC_METTL3_EV_vs_WT_F02.13857.13857.2 0.0192 14-Sep K.QVEELFER[166.11].K "sp|P78347|GTF2I_HUMAN,tr|A0A494C1K3|A0A494C1K3_HUMAN" 2 1058.5272 1.5 14070 13857 2 1058.527612 530.2709 General transcription factor II-I OS=Homo sapiens OX=9606 GN=GTF2I PE=1 SV=2 4.25 2815.8 - 6.28E+06 - - - 0.3939 - 1.765 0.307 - 431.2 1 2 0 0.0004 8 0 0 0 1.66E+09 1.10E+09 - - - 3.0219 0.999 221125_WJC_METTL3_EV_vs_WT_F02.13858.13858.2 0.0577 16-Aug R.SSLLVGNLK.K "sp|Q8IXK0|PHC2_HUMAN,tr|A0A0A0MSI2|A0A0A0MSI2_HUMAN,tr|B3KPJ4|B3KPJ4_HUMAN" 3 929.5546 1.6 14071 13858 2 929.554809 465.7846 Polyhomeotic-like protein 2 OS=Homo sapiens OX=9606 GN=PHC2 PE=1 SV=1 8.47 2815.8 - 2.51E+06 - - - 0.2442 - 1.485 0.303 - 155.4 1 2 0 0.0002 9 0 0 0 1.85E+08 1.16E+08 - - - 2.4228 0.9991 221125_WJC_METTL3_EV_vs_WT_F02.13859.13859.2 0.0337 14-Aug K.SNSLAFIK[136.11].R "sp|Q14204|DYHC1_HUMAN,tr|A0A7P0T8N2|A0A7P0T8N2_HUMAN,tr|A0A7P0T9C4|A0A7P0T9C4_HUMAN,tr|A0A7P0TBJ7|A0A7P0TBJ7_HUMAN,tr|A0A804HHY6|A0A804HHY6_HUMAN,tr|A0A7P0T9K2|A0A7P0T9K2_HUMAN,tr|A0A7P0TB64|A0A7P0TB64_HUMAN,tr|A0A2R8Y706|A0A2R8Y706_HUMAN,tr|A0A7P0T916|A0A7P0T916_HUMAN,tr|A0A7P0TB75|A0A7P0TB75_HUMAN,tr|A0A7P0T8W5|A0A7P0T8W5_HUMAN,tr|A0A7P0T9S3|A0A7P0T9S3_HUMAN,tr|A0A7P0TAF3|A0A7P0TAF3_HUMAN,tr|A0A7P0T9F1|A0A7P0T9F1_HUMAN,tr|A0A7P0TAW9|A0A7P0TAW9_HUMAN,tr|A0A2R8YGC7|A0A2R8YGC7_HUMAN,tr|A0A7P0TA13|A0A7P0TA13_HUMAN,tr|A0A7P0T934|A0A7P0T934_HUMAN,tr|A0A7P0TAV5|A0A7P0TAV5_HUMAN,tr|A0A7P0T9Y3|A0A7P0T9Y3_HUMAN,tr|A0A7P0T7V5|A0A7P0T7V5_HUMAN,tr|A0A7P0T9R4|A0A7P0T9R4_HUMAN,tr|A0A2R8Y5T0|A0A2R8Y5T0_HUMAN,tr|A0A7P0T990|A0A7P0T990_HUMAN,tr|A0A7P0T942|A0A7P0T942_HUMAN,tr|A0A7P0TAS7|A0A7P0TAS7_HUMAN,tr|A0A2R8YFZ7|A0A2R8YFZ7_HUMAN,tr|A0A7P0T825|A0A7P0T825_HUMAN,tr|A0A2R8Y6H2|A0A2R8Y6H2_HUMAN,tr|A0A7P0TBC9|A0A7P0TBC9_HUMAN,tr|A0A7P0TAM4|A0A7P0TAM4_HUMAN" 31 886.5004 0.77 14072 13859 2 886.499891 444.2575 Cytoplasmic dynein 1 heavy chain 1 OS=Homo sapiens OX=9606 GN=DYNC1H1 PE=1 SV=5 8.47 2815.9 - 606796 - - - -0.5381 - 1.411 0.328 - 223.5 1 2 0 -0.0005 8 0 0 0 3.17E+07 4.11E+07 - - - 2.5018 0.9997 221125_WJC_METTL3_EV_vs_WT_F02.13861.13861.2 0.00182 16-Sep K.EMEQLVLDK.K sp|Q96A49|SYAP1_HUMAN 1 1103.5533 1.28 14073 13861 2 1103.553969 552.7839 Synapse-associated protein 1 OS=Homo sapiens OX=9606 GN=SYAP1 PE=1 SV=1 4.14 2816.1 - 5.34E+07 - - - 0.6416 - 1.721 0.428 - 390.3 1 2 0 0.0007 9 0 0 0 2.34E+09 1.82E+09 - - - 3.7726 0.9956 221125_WJC_METTL3_EV_vs_WT_F02.13863.13863.2 0.458 12-Jul K.ALDDFYK[136.11].M sp|Q9BRX2|PELO_HUMAN 1 878.4265 0.66 14074 13863 2 878.426582 440.2205 Protein pelota homolog OS=Homo sapiens OX=9606 GN=PELO PE=1 SV=2 4.21 2816.4 - 1.91E+06 - - - 0.0546 - 1.391 0.151 - 141.8 1 2 0 0 7 0 0 0 3.72E+07 5.67E+07 - - - 1.202 0.9906 221125_WJC_METTL3_EV_vs_WT_F02.13864.13864.2 0.297 12-May K.QAYLDFK.G sp|Q8WXX5|DNJC9_HUMAN 1 883.444 0.67 14075 13864 2 883.443861 442.7293 DnaJ homolog subfamily C member 9 OS=Homo sapiens OX=9606 GN=DNAJC9 PE=1 SV=1 5.83 2816.4 - 1.40E+06 - - - -0.1222 - 1.152 0.158 - 109.9 1 2 0 -0.0001 7 0 0 0 4.55E+07 6.82E+07 - - - 0.6563 0.9998 221125_WJC_METTL3_EV_vs_WT_F02.13865.13865.2 0.00323 16-Nov K.LSEIVTLAK[136.11].Q "sp|Q9P2R7|SUCB1_HUMAN,tr|A0A2R8YDQ9|A0A2R8YDQ9_HUMAN,tr|A0A0U1RQL1|A0A0U1RQL1_HUMAN,tr|A0A2R8Y6Y7|A0A2R8Y6Y7_HUMAN" 4 980.5997 1.67 14076 13865 2 980.600399 491.3072 "Succinate--CoA ligase [ADP-forming] subunit beta, mitochondrial OS=Homo sapiens OX=9606 GN=SUCLA2 PE=1 SV=3" 6 2816.5 - 1.07E+06 - - - 0.6639 - 2.231 0.445 - 281.8 1 2 0 0.0007 9 0 0 0 4.17E+07 2.49E+07 - - - 4.6491 0.9998 221125_WJC_METTL3_EV_vs_WT_F02.13866.13866.2 0.000213 14-Aug K.FTEEIPLK[136.11].L sp|O00425|IF2B3_HUMAN 1 983.5419 1.6 14077 13866 2 983.541595 492.7782 Insulin-like growth factor 2 mRNA-binding protein 3 OS=Homo sapiens OX=9606 GN=IGF2BP3 PE=1 SV=2 4.53 2816.6 - 2.54E+06 - - - -0.3081 - 1.699 0.473 - 205.2 1 2 0 -0.0003 8 0 0 0 3.05E+08 1.91E+08 - - - 4.1331 0.9991 221125_WJC_METTL3_EV_vs_WT_F02.13867.13867.2 0.00236 18-Jul R.LVGLEAPSVR.E sp|Q8NBN7|RDH13_HUMAN 1 1039.6026 0.76 14078 13867 2 1039.604616 520.8086 Retinol dehydrogenase 13 OS=Homo sapiens OX=9606 GN=RDH13 PE=1 SV=2 6 2816.7 - 549309 - - - 1.944 - 1.705 0.368 - 110.8 1 2 0 0.002 10 0 0 0 7.21E+07 9.52E+07 - - - 3.2478 1 221125_WJC_METTL3_EV_vs_WT_F02.13868.13868.2 1.02E-07 22-Nov K.IGDGMNAYVAYK[136.11].V sp|Q13596|SNX1_HUMAN 1 1308.6264 1.86 14079 13868 2 1308.618308 655.3205 Sorting nexin-1 OS=Homo sapiens OX=9606 GN=SNX1 PE=1 SV=3 5.83 2816.8 - 236728 - - - -6.163 - 2.47 0.589 - 524.1 1 2 0 -0.0081 12 0 0 0 1.13E+07 6.04E+06 - - - 5.768 0.9997 221125_WJC_METTL3_EV_vs_WT_F02.13871.13871.2 0.00447 18-Nov K.LVNEVTEFAK.T "sp|P02768|ALBU_HUMAN,tr|A0A087WWT3|A0A087WWT3_HUMAN,tr|H7C013|H7C013_HUMAN,tr|A0A0C4DGB6|A0A0C4DGB6_HUMAN" 4 1148.6077 29.18 14080 13871 2 1148.610001 575.3111 Albumin OS=Homo sapiens OX=9606 GN=ALB PE=1 SV=2 4.53 2817.2 - 1.77E+06 - - - 1.9685 - 2.206 0.455 - 413 1 2 0 0.0023 10 0 0 0 6.52E+08 2.23E+07 - - - 4.6093 0.9996 221125_WJC_METTL3_EV_vs_WT_F02.13873.13873.2 0.000278 14-Aug K.GYGFGMVK[136.11].L "sp|Q9Y277|VDAC3_HUMAN,tr|E5RHE1|E5RHE1_HUMAN,tr|E5RJN6|E5RJN6_HUMAN,tr|E5RFL1|E5RFL1_HUMAN,tr|E5RFP6|E5RFP6_HUMAN,tr|E5RHZ6|E5RHZ6_HUMAN" 6 865.4248 0.86 14081 13873 2 865.424209 433.7197 Voltage-dependent anion-selective channel protein 3 OS=Homo sapiens OX=9606 GN=VDAC3 PE=1 SV=1 8.59 2817.4 - 2.44E+06 - - - -0.6367 - 1.488 0.425 - 192.3 1 2 0 -0.0006 8 0 0 0 8.29E+07 9.59E+07 - - - 3.3785 0.9541 221125_WJC_METTL3_EV_vs_WT_F02.13874.13874.2 5.28 12-May K.ALADYIR.Q "sp|Q9BS26|ERP44_HUMAN,sp|P43034|LIS1_HUMAN,tr|A0A6Q8PFU3|A0A6Q8PFU3_HUMAN,tr|I3L495|I3L495_HUMAN,tr|A0A6Q8PG63|A0A6Q8PG63_HUMAN" 5 820.4443 1.68 14082 13874 2 820.444074 411.2294 Endoplasmic reticulum resident protein 44 OS=Homo sapiens OX=9606 GN=ERP44 PE=1 SV=1 5.88 2817.5 - 1.16E+06 - - - -0.2791 - 1.07 0.049 - 95.1 1 2 0 -0.0002 7 0 0 0 6.18E+07 3.68E+07 - - - -0.3828 0.8049 221125_WJC_METTL3_EV_vs_WT_F02.13876.13876.2 0.0405 24-Jun R.VVYGGGAAEISC[160.03]A.L "sp|P48643|TCPE_HUMAN,tr|E9PCA1|E9PCA1_HUMAN,tr|B7ZAR1|B7ZAR1_HUMAN,tr|E7ENZ3|E7ENZ3_HUMAN" 4 1252.5758 - 14084 13876 2 1252.573407 627.2952 T-complex protein 1 subunit epsilon OS=Homo sapiens OX=9606 GN=CCT5 PE=1 SV=1 4 2817.7 - 289144 - - - -1.9009 - 1.157 0.322 - 103.7 1 1 0 -0.0024 13 0 0 0 - - - - - 1.7928 0.8222 221125_WJC_METTL3_EV_vs_WT_F02.13888.13888.2 0.453 14-May R.LASYLDKV.R "sp|Q04695|K1C17_HUMAN,sp|Q99456|K1C12_HUMAN,sp|P13645|K1C10_HUMAN,sp|P02533|K1C14_HUMAN,sp|P08727|K1C19_HUMAN,sp|P35527|K1C9_HUMAN,sp|P08779|K1C16_HUMAN,sp|P19012|K1C15_HUMAN,tr|K7EPJ9|K7EPJ9_HUMAN,tr|C9JM50|C9JM50_HUMAN,tr|A0A1B0GVI3|A0A1B0GVI3_HUMAN,tr|A0A3B3ITG2|A0A3B3ITG2_HUMAN" 12 907.5015 0.85 14090 13888 2 907.501174 454.758 "Keratin, type I cytoskeletal 17 OS=Homo sapiens OX=9606 GN=KRT17 PE=1 SV=2" 5.83 2819.2 - 5.08E+06 - - - -0.3416 - 1.332 0.224 - 45.1 3 1 0 -0.0003 8 0 0 0 1.18E+08 1.39E+08 - - - 1.3469 0.9989 221125_WJC_METTL3_EV_vs_WT_F02.13889.13889.2 0.00264 14-Jul K.SNSLAFIK.R "sp|Q14204|DYHC1_HUMAN,tr|A0A7P0T8N2|A0A7P0T8N2_HUMAN,tr|A0A7P0T9C4|A0A7P0T9C4_HUMAN,tr|A0A7P0TBJ7|A0A7P0TBJ7_HUMAN,tr|A0A804HHY6|A0A804HHY6_HUMAN,tr|A0A7P0T9K2|A0A7P0T9K2_HUMAN,tr|A0A7P0TB64|A0A7P0TB64_HUMAN,tr|A0A2R8Y706|A0A2R8Y706_HUMAN,tr|A0A7P0T916|A0A7P0T916_HUMAN,tr|A0A7P0TB75|A0A7P0TB75_HUMAN,tr|A0A7P0T8W5|A0A7P0T8W5_HUMAN,tr|A0A7P0T9S3|A0A7P0T9S3_HUMAN,tr|A0A7P0TAF3|A0A7P0TAF3_HUMAN,tr|A0A7P0T9F1|A0A7P0T9F1_HUMAN,tr|A0A7P0TAW9|A0A7P0TAW9_HUMAN,tr|A0A2R8YGC7|A0A2R8YGC7_HUMAN,tr|A0A7P0TA13|A0A7P0TA13_HUMAN,tr|A0A7P0T934|A0A7P0T934_HUMAN,tr|A0A7P0TAV5|A0A7P0TAV5_HUMAN,tr|A0A7P0T9Y3|A0A7P0T9Y3_HUMAN,tr|A0A7P0T7V5|A0A7P0T7V5_HUMAN,tr|A0A7P0T9R4|A0A7P0T9R4_HUMAN,tr|A0A2R8Y5T0|A0A2R8Y5T0_HUMAN,tr|A0A7P0T990|A0A7P0T990_HUMAN,tr|A0A7P0T942|A0A7P0T942_HUMAN,tr|A0A7P0TAS7|A0A7P0TAS7_HUMAN,tr|A0A2R8YFZ7|A0A2R8YFZ7_HUMAN,tr|A0A7P0T825|A0A7P0T825_HUMAN,tr|A0A2R8Y6H2|A0A2R8Y6H2_HUMAN,tr|A0A7P0TBC9|A0A7P0TBC9_HUMAN,tr|A0A7P0TAM4|A0A7P0TAM4_HUMAN" 31 878.4862 0.76 14091 13889 2 878.484951 440.2504 Cytoplasmic dynein 1 heavy chain 1 OS=Homo sapiens OX=9606 GN=DYNC1H1 PE=1 SV=5 8.47 2819.3 - 1.31E+06 - - - -1.3853 - 1.374 0.352 - 132.2 1 2 0 -0.0012 8 0 0 0 3.18E+07 4.20E+07 - - - 2.5987 0.9944 221125_WJC_METTL3_EV_vs_WT_F02.13896.13896.2 2.56 12-Aug K.TVYSILR.H "sp|P05198|IF2A_HUMAN,tr|H0YJS4|H0YJS4_HUMAN,tr|G3V4T5|G3V4T5_HUMAN" 3 850.4913 0.67 14096 13896 2 850.490264 426.2529 Eukaryotic translation initiation factor 2 subunit 1 OS=Homo sapiens OX=9606 GN=EIF2S1 PE=1 SV=3 8.41 2820.2 - 8.38E+06 - - - -1.1629 - 1.332 0.169 - 207.3 1 2 0 -0.001 7 0 0 0 1.84E+08 2.77E+08 - - - 1.1973 0.9781 221125_WJC_METTL3_EV_vs_WT_F02.13897.13897.2 0.245 16-Aug K.TIVMGASFR.N "sp|P37837|TALDO_HUMAN,tr|F2Z393|F2Z393_HUMAN" 2 980.5113 2.74 14097 13897 2 980.509943 491.2629 Transaldolase OS=Homo sapiens OX=9606 GN=TALDO1 PE=1 SV=2 9.41 2820.3 - 805935 - - - -1.4217 - 1.386 0.05 - 142.4 1 2 0 -0.0014 9 0 0 0 1.97E+07 7.18E+06 - - - 0.3542 0.9997 221125_WJC_METTL3_EV_vs_WT_F02.13898.13898.2 0.00274 16-Oct R.VC[160.03]VIDEIGK.M "sp|Q9BSD7|NTPCR_HUMAN,tr|Q5TDF0|Q5TDF0_HUMAN" 2 1031.5321 0.92 14098 13898 2 1031.533094 516.7733 Cancer-related nucleoside-triphosphatase OS=Homo sapiens OX=9606 GN=NTPCR PE=1 SV=1 4.37 2820.4 - 1.05E+06 - - - 0.9326 - 1.914 0.383 - 331.6 1 2 0 0.001 9 0 0 0 1.08E+09 1.17E+09 - - - 3.7477 0.9996 221125_WJC_METTL3_EV_vs_WT_F02.13903.13903.2 0.00474 16-Oct R.VC[160.03]VIDEIGK[136.11].M "sp|Q9BSD7|NTPCR_HUMAN,tr|Q5TDF0|Q5TDF0_HUMAN" 2 1039.5463 0.92 14101 13903 2 1039.545658 520.7804 Cancer-related nucleoside-triphosphatase OS=Homo sapiens OX=9606 GN=NTPCR PE=1 SV=1 4.37 2821 - 2.48E+06 - - - -0.6484 - 1.881 0.336 - 323 1 2 0 -0.0007 9 0 0 0 1.08E+09 1.17E+09 - - - 3.3503 0.9998 221125_WJC_METTL3_EV_vs_WT_F02.13904.13904.2 0.00353 18-Sep K.GVAVDYLPER.Q sp|P13674|P4HA1_HUMAN 1 1117.5768 1.61 14102 13904 2 1117.5763 559.7957 Prolyl 4-hydroxylase subunit alpha-1 OS=Homo sapiens OX=9606 GN=P4HA1 PE=1 SV=2 4.37 2821 - 1.11E+07 - - - -0.4241 - 2.104 0.456 - 448.1 1 2 0 -0.0005 10 0 0 0 3.93E+08 2.43E+08 - - - 4.4852 0.9944 221125_WJC_METTL3_EV_vs_WT_F02.13905.13905.2 0.12 16-Sep R.K[136.11]PFYPALIR[166.11].Y "sp|O00746|NDKM_HUMAN,tr|Q4TT34|Q4TT34_HUMAN,tr|H0Y6J0|H0Y6J0_HUMAN,tr|F2Z2X0|F2Z2X0_HUMAN,tr|A2IDC9|A2IDC9_HUMAN" 5 1121.6716 2.54 14103 13905 2 1121.675141 561.8431 "Nucleoside diphosphate kinase, mitochondrial OS=Homo sapiens OX=9606 GN=NME4 PE=1 SV=1" 9.99 2821.1 - 1.40E+06 - - - 3.1382 - 1.57 0.262 - 315.3 1 2 0 0.0035 9 0 0 0 1.15E+08 4.53E+07 - - - 2.28 0.9254 221125_WJC_METTL3_EV_vs_WT_F02.13911.13911.2 2.1 16-Oct K.TISNGFGFK.D "sp|P04049|RAF1_HUMAN,tr|A0A0B4J1W9|A0A0B4J1W9_HUMAN" 2 969.492 1.01 14107 13911 2 969.492423 485.7533 RAF proto-oncogene serine\threonine-protein kinase OS=Homo sapiens OX=9606 GN=RAF1 PE=1 SV=1 8.41 2821.8 - 532591 - - - 0.4549 - 0.872 0.095 - 159.2 1 2 0 0.0004 9 0 0 0 2.39E+07 2.36E+07 - - - -0.6537 0.9873 221125_WJC_METTL3_EV_vs_WT_F02.13917.13917.2 5.08E-05 18-Jul R.FATSEELLSH.L "sp|Q9H7S9|ZN703_HUMAN,sp|Q96F45|ZN503_HUMAN" 2 1132.5401 - 14111 13917 2 1132.539735 567.2773 Zinc finger protein 703 OS=Homo sapiens OX=9606 GN=ZNF703 PE=1 SV=1 4.51 2822.4 - 1.72E+06 - - - -0.2817 - 1.651 0.481 - 131.8 1 1 0 -0.0003 10 0 0 0 - - - - - 3.9931 0.9925 221125_WJC_METTL3_EV_vs_WT_F02.13925.13925.2 0.0853 14-Aug K.SIPTLISR.L "sp|P18754|RCC1_HUMAN,tr|C9JW69|C9JW69_HUMAN" 2 885.5284 0.54 14117 13925 2 885.526857 443.7715 Regulator of chromosome condensation OS=Homo sapiens OX=9606 GN=RCC1 PE=1 SV=1 9.47 2823.3 - 1.30E+06 - - - -1.7052 - 1.234 0.209 - 220.7 1 2 0 -0.0015 8 0 0 0 5.23E+07 9.65E+07 - - - 1.2183 0.9999 221125_WJC_METTL3_EV_vs_WT_F02.13926.13926.3 0.000127 13/36 R.ISGLIYEETR.G sp|P62805|H4_HUMAN 1 1179.6136 1.25 14118 13926 3 1179.610865 394.2118 Histone H4 OS=Homo sapiens OX=9606 GN=H4C1 PE=1 SV=2 4.53 2823.4 - 1.08E+06 - - - -2.2787 - 2.103 0.462 - 243.5 1 2 0 -0.0027 10 0 0 0 1.65E+07 1.32E+07 - - - 5.861 0.9996 221125_WJC_METTL3_EV_vs_WT_F02.13928.13928.2 0.00109 16-Jul K.EMEQLVLDK[136.11].K sp|Q96A49|SYAP1_HUMAN 1 1111.5675 1.29 14119 13928 2 1111.566628 556.791 Synapse-associated protein 1 OS=Homo sapiens OX=9606 GN=SYAP1 PE=1 SV=1 4.14 2823.6 - 1.59E+07 - - - -0.7494 - 1.603 0.406 - 237.3 1 2 0 -0.0008 9 0 0 0 2.36E+09 1.82E+09 - - - 3.4046 0.9988 221125_WJC_METTL3_EV_vs_WT_F02.13931.13931.2 0.0452 14-Jul K.SIPTLISR[166.11].L "sp|P18754|RCC1_HUMAN,tr|C9JW69|C9JW69_HUMAN" 2 895.5366 0.55 14121 13931 2 895.535764 448.7756 Regulator of chromosome condensation OS=Homo sapiens OX=9606 GN=RCC1 PE=1 SV=1 9.47 2823.9 - 2.47E+06 - - - -0.9748 - 1.299 0.341 - 160.8 1 2 0 -0.0009 8 0 0 0 5.23E+07 9.44E+07 - - - 2.3483 1 221125_WJC_METTL3_EV_vs_WT_F02.13932.13932.2 3.41E-05 18-Nov R.MDSFDEDLAR.P "sp|Q9Y2W1|TR150_HUMAN,tr|A0A3B3ITZ9|A0A3B3ITZ9_HUMAN" 2 1197.4972 3.02 14122 13932 2 1197.495278 599.7559 Thyroid hormone receptor-associated protein 3 OS=Homo sapiens OX=9606 GN=THRAP3 PE=1 SV=2 3.84 2824 - 3.74E+06 - - - -1.6075 - 2.381 0.62 - 718.5 1 1 0 -0.0019 10 0 0 0 1.51E+08 4.98E+07 - - - 6.0412 0.9887 221125_WJC_METTL3_EV_vs_WT_F02.13933.13933.2 0.133 18-Aug K.QAIGIALETR.R "sp|Q99460|PSMD1_HUMAN,tr|A0A7I2V4X0|A0A7I2V4X0_HUMAN,tr|A0A7I2V2K8|A0A7I2V2K8_HUMAN,tr|A0A7I2YQY1|A0A7I2YQY1_HUMAN,tr|A0A7I2V523|A0A7I2V523_HUMAN,tr|A0A7I2V641|A0A7I2V641_HUMAN,tr|H7BZR6|H7BZR6_HUMAN,tr|A0A7I2V491|A0A7I2V491_HUMAN,tr|A0A7I2YQI9|A0A7I2YQI9_HUMAN,tr|C9J9M4|C9J9M4_HUMAN,tr|A0A7I2V262|A0A7I2V262_HUMAN,tr|A0A087WW66|A0A087WW66_HUMAN,tr|A0A7P0MW50|A0A7P0MW50_HUMAN,tr|A0A7I2V4A5|A0A7I2V4A5_HUMAN,tr|A0A7I2V5C8|A0A7I2V5C8_HUMAN,tr|A0A7I2V479|A0A7I2V479_HUMAN" 16 1070.6084 1.04 14123 13933 2 1070.607252 536.3115 26S proteasome non-ATPase regulatory subunit 1 OS=Homo sapiens OX=9606 GN=PSMD1 PE=1 SV=2 6 2824 - 1.19E+06 - - - -1.0798 - 1.343 0.129 - 109.8 2 2 0 -0.0012 10 0 0 0 8.94E+07 8.62E+07 - - - 0.6821 0.9326 221125_WJC_METTL3_EV_vs_WT_F02.13937.13937.2 0.00958 18-Sep R.TLAMLDEEPK[136.11].T "sp|P35251|RFC1_HUMAN,tr|A0A1W2PP02|A0A1W2PP02_HUMAN" 2 1153.578 2.43 14127 13937 2 1153.570055 577.7963 Replication factor C subunit 1 OS=Homo sapiens OX=9606 GN=RFC1 PE=1 SV=4 4.14 2824.5 - 417745 - - - -6.9098 - 1.408 0.321 - 203.1 1 2 0 -0.008 10 0 0 0 1.47E+07 6.05E+06 - - - 2.3645 0.9831 221125_WJC_METTL3_EV_vs_WT_F02.13941.13941.2 0.00252 18-Nov R.MDSFDEDLAR[166.11].P "sp|Q9Y2W1|TR150_HUMAN,tr|A0A3B3ITZ9|A0A3B3ITZ9_HUMAN" 2 1207.5055 3.02 14129 13941 2 1207.502422 604.76 Thyroid hormone receptor-associated protein 3 OS=Homo sapiens OX=9606 GN=THRAP3 PE=1 SV=2 3.84 2824.9 - 2.12E+06 - - - -2.5267 - 2.279 0.557 - 575.2 1 1 0 -0.0031 10 0 0 0 1.51E+08 4.98E+07 - - - 5.4533 0.9992 221125_WJC_METTL3_EV_vs_WT_F02.13942.13942.2 0.00357 14-Sep R.IDLLAQPR[166.11].R "sp|Q5SW79|CE170_HUMAN,tr|H0Y2V6|H0Y2V6_HUMAN" 2 934.5475 1.35 14130 13942 2 934.550018 468.281 Centrosomal protein of 170 kDa OS=Homo sapiens OX=9606 GN=CEP170 PE=1 SV=1 5.84 2825 - 1.42E+06 - - - 2.6558 - 2.114 0.356 - 252.2 1 2 0 0.0025 8 0 0 0 8.30E+07 6.14E+07 - - - 3.9273 0.9528 221125_WJC_METTL3_EV_vs_WT_F02.13947.13947.2 0.0902 18-Aug R.LSPEQLEEVR[166.11].E "sp|P15735|PHKG2_HUMAN,tr|J3KNN3|J3KNN3_HUMAN,tr|H3BTW6|H3BTW6_HUMAN,tr|H3BP07|H3BP07_HUMAN" 4 1208.6276 0.14 14134 13947 2 1208.626478 605.3211 "Phosphorylase b kinase gamma catalytic chain, liver\testis isoform OS=Homo sapiens OX=9606 GN=PHKG2 PE=1 SV=1" 4.25 2825.6 - 2.08E+06 - - - -0.9589 - 1.221 0.014 - 143.2 1 2 0 -0.0012 10 0 0 0 5.48E+07 3.82E+08 - - - -0.2986 0.9956 221125_WJC_METTL3_EV_vs_WT_F02.13953.13953.2 0.0306 16-Jul K.AFADPEVLR[166.11].R "sp|O75179|ANR17_HUMAN,sp|Q8IWZ3|ANKH1_HUMAN,tr|E9PDP5|E9PDP5_HUMAN,tr|H0YM23|H0YM23_HUMAN,tr|A0A1W2PQ15|A0A1W2PQ15_HUMAN" 5 1026.5374 1.57 14137 13953 2 1026.536148 514.276 Ankyrin repeat domain-containing protein 17 OS=Homo sapiens OX=9606 GN=ANKRD17 PE=1 SV=3 4.37 2826.3 - 1.40E+06 - - - -1.1855 - 1.314 0.211 - 169.7 1 2 0 -0.0012 9 0 0 0 1.56E+08 9.94E+07 - - - 1.3891 0.9823 221125_WJC_METTL3_EV_vs_WT_F02.13955.13955.2 0.000464 16-Aug F.SLATNEMWR.S "sp|Q04837|SSBP_HUMAN,tr|C9K0U8|C9K0U8_HUMAN,tr|A0A0G2JLD8|A0A0G2JLD8_HUMAN,tr|E7EUY5|E7EUY5_HUMAN" 4 1106.5179 1.47 14139 13955 2 1106.51632 554.2662 "Single-stranded DNA-binding protein, mitochondrial OS=Homo sapiens OX=9606 GN=SSBP1 PE=1 SV=1" 5.72 2826.4 - 3.49E+06 - - - -1.4089 - 1.79 0.451 - 206.8 1 1 0 -0.0016 9 0 0 0 9.70E+07 6.62E+07 - - - 4.056 0.9924 221125_WJC_METTL3_EV_vs_WT_F02.13959.13959.2 0.147 14-Jul K.SLTVIPYK.C sp|Q9H8H0|NOL11_HUMAN 1 919.5379 0.24 14141 13959 2 919.536465 460.7762 Nucleolar protein 11 OS=Homo sapiens OX=9606 GN=NOL11 PE=1 SV=1 8.31 2826.9 - 1.33E+06 - - - -1.5269 - 1.322 0.169 - 167.6 1 2 0 -0.0014 8 0 0 0 4.09E+07 1.68E+08 - - - 1.1307 0.9989 221125_WJC_METTL3_EV_vs_WT_F02.13960.13960.2 0.0136 20-Nov K.LIADVAPSAIR[166.11].E "sp|P39748|FEN1_HUMAN,tr|F5H1Y3|F5H1Y3_HUMAN" 2 1134.6636 0.53 14142 13960 2 1134.661856 568.3391 Flap endonuclease 1 OS=Homo sapiens OX=9606 GN=FEN1 PE=1 SV=1 5.84 2826.9 - 1.37E+06 - - - -1.5626 - 1.89 0.262 - 324.6 1 2 0 -0.0018 11 0 0 0 7.21E+07 1.36E+08 - - - 2.6977 0.9962 221125_WJC_METTL3_EV_vs_WT_F02.13961.13961.2 0.0234 20-Sep R.QPLLGPPESMR[166.11].E "sp|Q99613|EIF3C_HUMAN,sp|B5ME19|EIFCL_HUMAN" 2 1233.6415 2 14143 13961 2 1233.642485 617.828 Eukaryotic translation initiation factor 3 subunit C OS=Homo sapiens OX=9606 GN=EIF3C PE=1 SV=1 6 2827.1 - 563537 - - - 0.7879 - 1.39 0.205 - 136.9 1 2 0 0.001 11 0 0 0 4.30E+07 2.15E+07 - - - 1.4457 0.999 221125_WJC_METTL3_EV_vs_WT_F02.13962.13962.2 0.00983 20-Aug R.LLESLEEQEVK.G "sp|Q86W74|ANR46_HUMAN,tr|J3KP26|J3KP26_HUMAN" 2 1315.6871 2.45 14144 13962 2 1315.685203 658.8508 Ankyrin repeat domain-containing protein 46 OS=Homo sapiens OX=9606 GN=ANKRD46 PE=1 SV=2 4.09 2827.2 - 391905 - - - -1.451 - 1.568 0.343 - 169.5 1 2 0 -0.0019 11 0 0 0 7.93E+06 3.23E+06 - - - 2.7906 0.9895 221125_WJC_METTL3_EV_vs_WT_F02.13967.13967.2 0.00101 22-Nov T.IIANPDIPEAYK.L "sp|P27694|RFA1_HUMAN,tr|I3L4R8|I3L4R8_HUMAN" 2 1342.7133 1.25 14147 13967 2 1342.713107 672.3639 Replication protein A 70 kDa DNA-binding subunit OS=Homo sapiens OX=9606 GN=RPA1 PE=1 SV=2 4.37 2827.8 - 309297 - - - -0.1192 - 2.081 0.444 - 364.6 1 1 0 -0.0002 12 0 0 0 1.04E+07 8.32E+06 - - - 4.2486 0.9654 221125_WJC_METTL3_EV_vs_WT_F02.13968.13968.2 0.166 18-Sep R.LMQGDEIC[160.03]LR.Y sp|Q92900|RENT1_HUMAN 1 1233.5846 1.01 14148 13968 2 1233.576975 617.7996 Regulator of nonsense transcripts 1 OS=Homo sapiens OX=9606 GN=UPF1 PE=1 SV=2 4.37 2827.9 - 534166 - - - -6.1633 - 1.451 0.334 - 166.5 1 2 0 -0.0076 10 0 0 0 2.05E+07 2.02E+07 - - - 2.5446 0.999 221125_WJC_METTL3_EV_vs_WT_F02.13972.13972.2 0.109 12-Aug R.FSGVPDR.F "sp|A0A075B6R9|KVD24_HUMAN,sp|A0A0C4DH68|KV224_HUMAN,sp|A2NJV5|KV229_HUMAN,sp|A0A075B6S2|KVD29_HUMAN,sp|A0A0A0MRZ7|KVD26_HUMAN" 5 776.3817 182.02 14150 13972 2 776.381665 389.1981 Probable non-functional immunoglobulin kappa variable 2D-24 OS=Homo sapiens OX=9606 GN=IGKV2D-24 PE=1 SV=1 5.84 2828.4 - 5.99E+06 - - - -0.0489 - 1.641 0.232 - 204.4 1 2 0 0 7 0 0 0 1.70E+08 9.36E+05 - - - 2.3239 0.9999 221125_WJC_METTL3_EV_vs_WT_F02.13973.13973.2 0.000679 20-Nov R.TIAETEAAYLK[136.11].L sp|O43805|SSNA1_HUMAN 1 1216.6431 2.61 14151 13973 2 1216.643787 609.3288 Sjoegren syndrome nuclear autoantigen 1 OS=Homo sapiens OX=9606 GN=SSNA1 PE=1 SV=2 4.53 2828.5 - 4.17E+06 - - - 0.5901 - 2.273 0.474 - 226.1 1 2 0 0.0007 11 0 0 0 3.85E+08 1.48E+08 - - - 4.763 0.9961 221125_WJC_METTL3_EV_vs_WT_F02.13975.13975.2 0.621 12-Jul K.FASFIDK.V "sp|Q86Y46|K2C73_HUMAN,sp|Q7RTS7|K2C74_HUMAN,sp|Q9NSB2|KRT84_HUMAN,sp|P48668|K2C6C_HUMAN,sp|Q3SY84|K2C71_HUMAN,sp|P05787|K2C8_HUMAN,sp|Q01546|K22O_HUMAN,sp|P19013|K2C4_HUMAN,sp|Q7Z794|K2C1B_HUMAN,sp|Q8N1N4|K2C78_HUMAN,sp|P12035|K2C3_HUMAN,sp|P04264|K2C1_HUMAN,sp|P04259|K2C6B_HUMAN,sp|P13647|K2C5_HUMAN,sp|P35908|K22E_HUMAN,sp|Q14CN4|K2C72_HUMAN,sp|P08729|K2C7_HUMAN,sp|O95678|K2C75_HUMAN,sp|Q5XKE5|K2C79_HUMAN,sp|P02538|K2C6A_HUMAN,tr|F8VUG2|F8VUG2_HUMAN,tr|F8W0C6|F8W0C6_HUMAN,tr|F8W1U3|F8W1U3_HUMAN,tr|H0YHD9|H0YHD9_HUMAN,tr|F8W1S1|F8W1S1_HUMAN,tr|F8VS61|F8VS61_HUMAN" 26 826.4225 2.8 14153 13975 2 826.421583 414.2185 "Keratin, type II cytoskeletal 73 OS=Homo sapiens OX=9606 GN=KRT73 PE=1 SV=1" 5.84 2828.6 - 1.48E+06 - - - -1.1157 - 1.442 0.17 - 134.7 1 2 0 -0.0009 7 0 0 0 7.91E+07 2.82E+07 - - - 1.4561 0.9993 221125_WJC_METTL3_EV_vs_WT_F02.13976.13976.2 0.176 14-Sep K.LALLEEAR.T "sp|Q5TZA2|CROCC_HUMAN,sp|P15311|EZRI_HUMAN,tr|E7EQR4|E7EQR4_HUMAN,tr|B1AKD8|B1AKD8_HUMAN" 4 913.5233 0.63 14154 13976 2 913.523079 457.7689 Rootletin OS=Homo sapiens OX=9606 GN=CROCC PE=1 SV=1 4.53 2828.7 - 1.25E+06 - - - -0.2222 - 2.008 0.212 - 242.2 1 2 0 -0.0002 8 0 0 0 4.57E+07 7.23E+07 - - - 2.7093 0.9737 221125_WJC_METTL3_EV_vs_WT_F02.13977.13977.2 0.000414 22-Oct T.IIANPDIPEAYK[136.11].L "sp|P27694|RFA1_HUMAN,tr|I3L4R8|I3L4R8_HUMAN" 2 1350.7275 2.09 14155 13977 2 1350.725559 676.371 Replication protein A 70 kDa DNA-binding subunit OS=Homo sapiens OX=9606 GN=RPA1 PE=1 SV=2 4.37 2828.8 - 380037 - - - -1.4126 - 1.669 0.429 - 277.7 1 1 0 -0.0019 12 0 0 0 1.86E+07 8.90E+06 - - - 3.5567 0.9981 221125_WJC_METTL3_EV_vs_WT_F02.13982.13982.2 0.00594 20-Aug K.LIADVAPSAIR.E "sp|P39748|FEN1_HUMAN,tr|F5H1Y3|F5H1Y3_HUMAN" 2 1124.6554 0.53 14158 13982 2 1124.654586 563.335 Flap endonuclease 1 OS=Homo sapiens OX=9606 GN=FEN1 PE=1 SV=1 5.84 2829.4 - 2.06E+06 - - - -0.6873 - 1.725 0.183 - 172.2 1 2 0 -0.0008 11 0 0 0 7.21E+07 1.36E+08 - - - 1.8674 0.9868 221125_WJC_METTL3_EV_vs_WT_F02.13983.13983.2 0.000185 20-Sep K.FEAHPNDLYVE.G "sp|P78347|GTF2I_HUMAN,tr|A0A494C0Q7|A0A494C0Q7_HUMAN,tr|A0A494C1K3|A0A494C1K3_HUMAN" 3 1332.5986 - 14159 13983 2 1332.598859 667.3066 General transcription factor II-I OS=Homo sapiens OX=9606 GN=GTF2I PE=1 SV=2 4.41 2829.5 - 1.68E+06 - - - 0.1703 - 1.7 0.472 - 309.7 1 1 0 0.0002 11 0 0 0 - - - - - 3.9626 0.9994 221125_WJC_METTL3_EV_vs_WT_F02.13984.13984.2 0.0048 18-Sep R.LGPSVVGLAR[166.11].Y "sp|Q14690|RRP5_HUMAN,tr|A0A3B3IUD7|A0A3B3IUD7_HUMAN" 2 977.5897 0.78 14160 13984 2 977.589414 489.8021 Protein RRP5 homolog OS=Homo sapiens OX=9606 GN=PDCD11 PE=1 SV=3 9.75 2829.6 - 2.20E+06 - - - -0.3284 - 1.488 0.364 - 157.3 1 2 0 -0.0003 10 0 0 0 2.94E+07 3.78E+07 - - - 2.8388 0.937 221125_WJC_METTL3_EV_vs_WT_F02.13989.13989.2 0.323 16-Jul F.SLATNEMWR[166.11].S "sp|Q04837|SSBP_HUMAN,tr|C9K0U8|C9K0U8_HUMAN,tr|A0A0G2JLD8|A0A0G2JLD8_HUMAN,tr|E7EUY5|E7EUY5_HUMAN" 4 1116.5261 1.46 14163 13989 2 1116.525109 559.2704 "Single-stranded DNA-binding protein, mitochondrial OS=Homo sapiens OX=9606 GN=SSBP1 PE=1 SV=1" 5.72 2830.2 - 3.01E+06 - - - -0.9315 - 1.522 0.291 - 138.1 1 1 0 -0.001 9 0 0 0 9.64E+07 6.59E+07 - - - 2.4052 0.9972 221125_WJC_METTL3_EV_vs_WT_F02.13994.13994.2 0.0204 22-Oct K.TVIEPMASEGLR.T "sp|P20020|AT2B1_HUMAN,tr|E7ERY9|E7ERY9_HUMAN" 2 1301.6649 1.13 14166 13994 2 1301.66565 651.8397 Plasma membrane calcium-transporting ATPase 1 OS=Homo sapiens OX=9606 GN=ATP2B1 PE=1 SV=4 4.53 2830.8 - 505381 - - - 0.5478 - 1.918 0.117 - 306.9 1 2 0 0.0007 12 0 0 0 1.10E+07 9.72E+06 - - - 1.6186 0.9642 221125_WJC_METTL3_EV_vs_WT_F02.14001.14001.2 0.83 12-Jun K.DIPVLPK.W "sp|Q96DR8|MUCL1_HUMAN,tr|F8VV13|F8VV13_HUMAN,tr|A0A087WWF8|A0A087WWF8_HUMAN" 3 780.4745 203.34 14171 14001 2 780.473901 391.2445 Mucin-like protein 1 OS=Homo sapiens OX=9606 GN=MUCL1 PE=1 SV=1 5.84 2831.5 - 3.36E+06 - - - -0.82 - 1.279 0.004 - 140.1 1 2 0 -0.0006 7 0 0 0 6.22E+07 3.06E+05 - - - -0.1499 0.9877 221125_WJC_METTL3_EV_vs_WT_F02.14002.14002.2 0.226 12-Aug R.FASFIER[166.11].V sp|P07196|NFL_HUMAN 1 878.4526 2.04 14172 14002 2 878.448793 440.2336 Neurofilament light polypeptide OS=Homo sapiens OX=9606 GN=NEFL PE=1 SV=3 6 2831.6 - 916403 - - - -4.303 - 1.65 0.228 - 181.9 1 2 0 -0.0038 7 0 0 0 1.62E+08 7.97E+07 - - - 2.3106 0.9775 221125_WJC_METTL3_EV_vs_WT_F02.14003.14003.2 0.248 14-Jun R.SLGAPVWR.E sp|Q6WKZ4|RFIP1_HUMAN 1 884.4868 2.27 14173 14003 2 884.486112 443.2507 Rab11 family-interacting protein 1 OS=Homo sapiens OX=9606 GN=RAB11FIP1 PE=1 SV=3 9.47 2831.7 - 898398 - - - -0.8197 - 0.977 0.16 - 119.5 1 2 0 -0.0007 8 0 0 0 6.27E+07 2.77E+07 - - - 0.1524 0.9992 221125_WJC_METTL3_EV_vs_WT_F02.14010.14010.2 0.204 18-Jul R.VLSIGDGIAR[166.11].V "sp|P25705|ATPA_HUMAN,tr|K7EQH4|K7EQH4_HUMAN,tr|K7ERX7|K7ERX7_HUMAN,tr|K7EK77|K7EK77_HUMAN,tr|K7EJP1|K7EJP1_HUMAN" 5 1009.5796 1.41 14179 14010 2 1009.579472 505.7971 "ATP synthase subunit alpha, mitochondrial OS=Homo sapiens OX=9606 GN=ATP5F1A PE=1 SV=1" 5.81 2832.6 - 2.30E+06 - - - -0.0921 - 1.592 0.309 - 145.3 1 2 0 -0.0001 10 0 0 0 1.26E+09 8.89E+08 - - - 2.6212 0.9958 221125_WJC_METTL3_EV_vs_WT_F02.14012.14012.2 0.192 12-Jul K.FYVEDLK.A "sp|O75400|PR40A_HUMAN,tr|A0A7N4I394|A0A7N4I394_HUMAN" 2 912.4593 1.22 14180 14012 2 912.457945 457.2369 Pre-mRNA-processing factor 40 homolog A OS=Homo sapiens OX=9606 GN=PRPF40A PE=1 SV=2 4.37 2832.8 - 1.02E+06 - - - -1.4675 - 1.282 0.231 - 170.1 1 2 0 -0.0013 7 0 0 0 5.79E+07 4.73E+07 - - - 1.5339 0.9997 221125_WJC_METTL3_EV_vs_WT_F02.14013.14013.2 6.49E-05 22-Nov R.YMGDLSGGQVLK[136.11].K "sp|P30519|HMOX2_HUMAN,tr|I3L159|I3L159_HUMAN,tr|A0A087WT44|A0A087WT44_HUMAN,tr|I3L1F5|I3L1F5_HUMAN" 4 1274.642 0.8 14181 14013 2 1274.640725 638.3283 Heme oxygenase 2 OS=Homo sapiens OX=9606 GN=HMOX2 PE=1 SV=2 5.83 2832.9 - 462596 - - - -1.0183 - 1.611 0.469 - 256.8 1 2 0 -0.0013 12 0 0 0 1.10E+07 1.38E+07 - - - 3.7593 0.9889 221125_WJC_METTL3_EV_vs_WT_F02.14016.14016.2 0.6 18-May R.VMEETPSILR.V sp|Q7L804|RFIP2_HUMAN 1 1173.6064 0.08 14184 14016 2 1173.60764 587.8105 Rab11 family-interacting protein 2 OS=Homo sapiens OX=9606 GN=RAB11FIP2 PE=1 SV=1 4.53 2833.2 - 243609 - - - 1.0915 - 1.256 0.199 - 59.9 7 2 0 0.0013 10 0 0 0 4.34E+06 5.44E+07 - - - 0.7691 0.9999 221125_WJC_METTL3_EV_vs_WT_F02.14017.14017.2 0.00068 13/24 K.LILYQEAAATNGR.V sp|Q9BTX1|NDC1_HUMAN 1 1418.7518 9.57 14185 14017 2 1418.753099 710.3832 Nucleoporin NDC1 OS=Homo sapiens OX=9606 GN=NDC1 PE=1 SV=2 6 2833.3 - 192809 - - - 0.9311 - 2.63 0.491 - 458.5 1 2 0 0.0013 13 0 0 0 1.59E+07 1.66E+06 - - - 5.1489 0.9999 221125_WJC_METTL3_EV_vs_WT_F02.14019.14019.2 0.000156 16-Oct K.YLVLDEADR.M "sp|O00571|DDX3X_HUMAN,sp|O15523|DDX3Y_HUMAN,sp|Q9NQI0|DDX4_HUMAN,sp|Q92841|DDX17_HUMAN,sp|P17844|DDX5_HUMAN,tr|A0A2R8YFR4|A0A2R8YFR4_HUMAN,tr|A0A2R8YCW1|A0A2R8YCW1_HUMAN,tr|A0A7I2V5F5|A0A7I2V5F5_HUMAN,tr|A0A2R8YDH3|A0A2R8YDH3_HUMAN,tr|A0A2R8YDT5|A0A2R8YDT5_HUMAN,tr|A0A2R8Y645|A0A2R8Y645_HUMAN,tr|A0A2R8YF78|A0A2R8YF78_HUMAN,tr|D6RCM4|D6RCM4_HUMAN,tr|J3KRZ1|J3KRZ1_HUMAN,tr|A0A0D9SFB3|A0A0D9SFB3_HUMAN,tr|A0A2R8YFS5|A0A2R8YFS5_HUMAN,tr|J3QSF1|J3QSF1_HUMAN,tr|A0A7I2V507|A0A7I2V507_HUMAN,tr|A0A5H1ZRQ2|A0A5H1ZRQ2_HUMAN,tr|A0A0D9SF53|A0A0D9SF53_HUMAN,tr|J3KTA4|J3KTA4_HUMAN,tr|A0A0G2JLI4|A0A0G2JLI4_HUMAN,tr|A0A1X7SBZ2|A0A1X7SBZ2_HUMAN,tr|A0A2R8Y5G6|A0A2R8Y5G6_HUMAN,tr|A0A2R8Y7T2|A0A2R8Y7T2_HUMAN,tr|A0A0D9SG12|A0A0D9SG12_HUMAN,tr|A0A7I2V2S0|A0A7I2V2S0_HUMAN,tr|F6S8Q4|F6S8Q4_HUMAN,tr|A0A2U3TZJ9|A0A2U3TZJ9_HUMAN,tr|A0A2R8Y4A4|A0A2R8Y4A4_HUMAN" 30 1092.5451 0.59 14186 14019 2 1092.545361 547.2798 ATP-dependent RNA helicase DDX3X OS=Homo sapiens OX=9606 GN=DDX3X PE=1 SV=3 4.03 2833.6 - 2.15E+07 - - - 0.2032 - 2.126 0.604 - 445.6 1 2 0 0.0002 9 0 0 0 1.90E+08 3.24E+08 - - - 5.6841 0.9991 221125_WJC_METTL3_EV_vs_WT_F02.14021.14021.2 0.00649 14-Sep K.ADEVVWVR.A "sp|P14868|SYDC_HUMAN,tr|C9JQM9|C9JQM9_HUMAN,tr|C9J7S3|C9J7S3_HUMAN,tr|H7C278|H7C278_HUMAN,tr|C9JLC1|C9JLC1_HUMAN" 5 972.5029 0.8 14187 14021 2 972.50029 487.2587 "Aspartate--tRNA ligase, cytoplasmic OS=Homo sapiens OX=9606 GN=DARS1 PE=1 SV=2" 4.37 2833.8 - 1.66E+06 - - - -2.6643 - 1.959 0.361 - 374.7 1 2 0 -0.0026 8 0 0 0 5.87E+07 7.35E+07 - - - 3.7346 0.9994 221125_WJC_METTL3_EV_vs_WT_F02.14022.14022.2 0.0262 20-Oct K.LAVLITNSNVR.H sp|P51570|GALK1_HUMAN 1 1198.7034 1.6 14188 14022 2 1198.70211 600.359 Galactokinase OS=Homo sapiens OX=9606 GN=GALK1 PE=1 SV=1 9.75 2833.9 - 859063 - - - -1.052 - 2.208 0.248 - 393 1 2 0 -0.0013 11 0 0 0 2.68E+08 1.68E+08 - - - 3.0151 0.9998 221125_WJC_METTL3_EV_vs_WT_F02.14025.14025.2 2.54E-06 22-Oct K.GVC[160.03]TEAGMYALR.E sp|P62195|PRS8_HUMAN 1 1326.606 1.34 14191 14025 2 1326.603983 664.3103 26S proteasome regulatory subunit 8 OS=Homo sapiens OX=9606 GN=PSMC5 PE=1 SV=1 5.99 2834.2 - 343935 - - - -1.5521 - 1.961 0.596 - 354.2 1 2 0 -0.0021 12 0 0 0 3.85E+07 2.87E+07 - - - 5.2144 0.9999 221125_WJC_METTL3_EV_vs_WT_F02.14027.14027.2 2.34E-06 24-Oct K.LILYQEAAATNGR[166.11].V sp|Q9BTX1|NDC1_HUMAN 1 1428.76 5.26 14193 14027 2 1428.75969 715.3873 Nucleoporin NDC1 OS=Homo sapiens OX=9606 GN=NDC1 PE=1 SV=2 6 2834.5 - 208114 - - - -0.2506 - 2.277 0.57 - 291.3 1 2 0 -0.0004 13 0 0 0 8.75E+06 1.66E+06 - - - 5.3628 0.9996 221125_WJC_METTL3_EV_vs_WT_F02.14029.14029.2 0.000503 16-Oct K.QIFLGGVDK.R "sp|P05141|ADT2_HUMAN,sp|P12236|ADT3_HUMAN" 2 975.5389 0.79 14194 14029 2 975.53862 488.7767 ADP\ATP translocase 2 OS=Homo sapiens OX=9606 GN=SLC25A5 PE=1 SV=7 5.84 2834.7 - 2.55E+06 - - - -0.3198 - 1.859 0.337 - 378.3 1 2 0 -0.0003 9 0 0 0 9.52E+07 1.20E+08 - - - 3.3238 0.9982 221125_WJC_METTL3_EV_vs_WT_F02.14030.14030.2 0.0977 14-Jul K.ESYYQLMK[136.11].T "sp|P19623|SPEE_HUMAN,tr|K7EQ47|K7EQ47_HUMAN" 2 1068.5041 3.75 14195 14030 2 1068.504727 535.2593 Spermidine synthase OS=Homo sapiens OX=9606 GN=SRM PE=1 SV=1 6.1 2834.8 - 1.83E+06 - - - 0.5559 - 1.363 0.269 - 133.1 1 2 0 0.0006 8 0 0 0 8.75E+07 2.34E+07 - - - 1.9617 0.9869 221125_WJC_METTL3_EV_vs_WT_F02.14031.14031.2 0.0244 16-Oct M.VWEGYNVVR[166.11].A "sp|O00746|NDKM_HUMAN,tr|Q4TT34|Q4TT34_HUMAN,tr|A0A087WVT9|A0A087WVT9_HUMAN,tr|H0Y6J0|H0Y6J0_HUMAN,tr|F2Z2X0|F2Z2X0_HUMAN" 5 1130.5748 2.12 14196 14031 2 1130.574707 566.2947 "Nucleoside diphosphate kinase, mitochondrial OS=Homo sapiens OX=9606 GN=NME4 PE=1 SV=1" 5.97 2834.8 - 8.21E+06 - - - -0.0938 - 1.835 0.426 - 417.7 1 1 0 -0.0001 9 0 0 0 4.58E+08 2.16E+08 - - - 3.9436 0.9967 221125_WJC_METTL3_EV_vs_WT_F02.14032.14032.2 0.0984 12-Jul R.FASFIER.V sp|P07196|NFL_HUMAN 1 868.4443 2.04 14197 14032 2 868.444083 435.2294 Neurofilament light polypeptide OS=Homo sapiens OX=9606 GN=NEFL PE=1 SV=3 6 2834.9 - 5.93E+06 - - - -0.2533 - 1.385 0.179 - 128.2 1 2 0 -0.0002 7 0 0 0 1.63E+08 7.99E+07 - - - 1.395 0.9994 221125_WJC_METTL3_EV_vs_WT_F02.14033.14033.2 0.00179 16-Sep K.YLDPEYIDR.L "sp|O75935|DCTN3_HUMAN,tr|X6RA56|X6RA56_HUMAN,tr|X6RLR1|X6RLR1_HUMAN,tr|A0A0A0MRV8|A0A0A0MRV8_HUMAN,tr|X6RCK5|X6RCK5_HUMAN" 5 1182.5557 2.76 14198 14033 2 1182.555988 592.2851 Dynactin subunit 3 OS=Homo sapiens OX=9606 GN=DCTN3 PE=1 SV=1 4.03 2834.9 - 2.47E+06 - - - 0.2402 - 1.48 0.376 - 247.7 1 2 0 0.0003 9 0 0 0 4.98E+07 1.81E+07 - - - 2.9522 0.9959 221125_WJC_METTL3_EV_vs_WT_F02.14036.14036.2 0.0702 14-Jul R.SEFTLMAK[136.11].R "sp|Q13190|STX5_HUMAN,tr|H7C3X5|H7C3X5_HUMAN,tr|E9PNU4|E9PNU4_HUMAN" 3 933.4721 0.99 14201 14036 2 933.472448 467.7433 Syntaxin-5 OS=Homo sapiens OX=9606 GN=STX5 PE=1 SV=2 5.72 2835.1 - 915872 - - - 0.3685 - 1.142 0.25 - 163 1 2 0 0.0003 8 0 0 0 3.65E+07 3.69E+07 - - - 1.2879 0.9999 221125_WJC_METTL3_EV_vs_WT_F02.14037.14037.2 8.50E-06 22-Nov K.GVC[160.03]TEAGMYALR[166.11].E sp|P62195|PRS8_HUMAN 1 1336.6143 1.07 14202 14037 2 1336.613585 669.3144 26S proteasome regulatory subunit 8 OS=Homo sapiens OX=9606 GN=PSMC5 PE=1 SV=1 5.99 2835.3 - 873980 - - - -0.5439 - 2.291 0.589 - 467.3 1 2 0 -0.0007 12 0 0 0 3.07E+07 2.87E+07 - - - 5.5723 0.9986 221125_WJC_METTL3_EV_vs_WT_F02.14038.14038.2 2.34E-06 18-Sep K.MVTPYANGWK[136.11].L "sp|O43251|RFOX2_HUMAN,tr|B0QYV1|B0QYV1_HUMAN,tr|B0QYY4|B0QYY4_HUMAN,tr|S4R469|S4R469_HUMAN,tr|A0A0G2JRD1|A0A0G2JRD1_HUMAN,tr|A0A0G2JRA5|A0A0G2JRA5_HUMAN,tr|S4R3K7|S4R3K7_HUMAN" 7 1173.5732 1.11 14203 14038 2 1173.568304 587.7939 RNA binding protein fox-1 homolog 2 OS=Homo sapiens OX=9606 GN=RBFOX2 PE=1 SV=3 8.34 2835.4 - 605605 - - - -4.1847 - 1.869 0.526 - 232.9 1 2 0 -0.0049 10 0 0 0 8.48E+08 7.64E+08 - - - 4.6702 0.9998 221125_WJC_METTL3_EV_vs_WT_F02.14039.14039.2 0.00075 18-Oct K.AYEMLSDPVK[136.11].R "sp|Q99543|DNJC2_HUMAN,tr|C9IZ83|C9IZ83_HUMAN,tr|H7C3L7|H7C3L7_HUMAN" 3 1159.5675 1.81 14204 14039 2 1159.566788 580.791 DnaJ homolog subfamily C member 2 OS=Homo sapiens OX=9606 GN=DNAJC2 PE=1 SV=4 4.37 2835.5 - 595360 - - - -0.5804 - 1.752 0.486 - 358.4 1 2 0 -0.0007 10 0 0 0 1.77E+07 9.76E+06 - - - 4.1956 0.9994 221125_WJC_METTL3_EV_vs_WT_F02.14042.14042.2 0.00273 22-Sep K.VVPQVETVDTLR[166.11].S "sp|Q9Y6R4|M3K4_HUMAN,tr|J3KNB8|J3KNB8_HUMAN,tr|F5H538|F5H538_HUMAN,tr|F5H4R1|F5H4R1_HUMAN" 4 1364.7539 27.62 14207 14042 2 1364.753845 683.3842 Mitogen-activated protein kinase kinase kinase 4 OS=Homo sapiens OX=9606 GN=MAP3K4 PE=1 SV=2 4.37 2835.8 - 296052 - - - -0.0403 - 1.628 0.346 - 242.7 1 2 0 -0.0001 12 0 0 0 1.06E+08 3.84E+06 - - - 2.8788 0.9982 221125_WJC_METTL3_EV_vs_WT_F02.14045.14045.2 0.154 14-Sep R.QIIGPFQR[166.11].F "sp|Q14683|SMC1A_HUMAN,tr|V9GYN9|V9GYN9_HUMAN" 2 967.5479 1.08 14209 14045 2 967.547073 484.7812 Structural maintenance of chromosomes protein 1A OS=Homo sapiens OX=9606 GN=SMC1A PE=1 SV=2 9.75 2836.2 - 4.17E+06 - - - -0.8237 - 1.619 0.201 - 305.3 1 2 0 -0.0008 8 0 0 0 1.08E+08 1.00E+08 - - - 1.9784 0.9964 221125_WJC_METTL3_EV_vs_WT_F02.14046.14046.2 0.623 14-Jun R.FTEDSLLR[166.11].H "sp|P26358|DNMT1_HUMAN,tr|A0A7I2V5D0|A0A7I2V5D0_HUMAN,tr|A0A7I2V5F1|A0A7I2V5F1_HUMAN,tr|A0A7I2V5F6|A0A7I2V5F6_HUMAN,tr|A0A7I2YQA8|A0A7I2YQA8_HUMAN,tr|A0A7I2YQQ0|A0A7I2YQQ0_HUMAN,tr|A0A7I2V311|A0A7I2V311_HUMAN,tr|A0A7I2V490|A0A7I2V490_HUMAN" 8 989.5057 0.75 14210 14046 2 989.506711 495.7601 DNA (cytosine-5)-methyltransferase 1 OS=Homo sapiens OX=9606 GN=DNMT1 PE=1 SV=2 4.37 2836.3 - 1.16E+06 - - - 0.9904 - 1.158 0.279 - 72.2 1 2 0 0.001 8 0 0 0 2.56E+07 3.40E+07 - - - 1.5438 0.9998 221125_WJC_METTL3_EV_vs_WT_F02.14049.14049.2 0.000213 18-Oct K.MVTPYANGWK.L "sp|O43251|RFOX2_HUMAN,tr|B0QYV1|B0QYV1_HUMAN,tr|B0QYY4|B0QYY4_HUMAN,tr|S4R469|S4R469_HUMAN,tr|A0A0G2JRD1|A0A0G2JRD1_HUMAN,tr|A0A0G2JRA5|A0A0G2JRA5_HUMAN,tr|S4R3K7|S4R3K7_HUMAN" 7 1165.559 1.11 14213 14049 2 1165.558756 583.7868 RNA binding protein fox-1 homolog 2 OS=Homo sapiens OX=9606 GN=RBFOX2 PE=1 SV=3 8.34 2836.5 - 2.21E+06 - - - -0.2222 - 1.91 0.464 - 322.2 1 2 0 -0.0003 10 0 0 0 8.48E+08 7.64E+08 - - - 4.2743 0.9997 221125_WJC_METTL3_EV_vs_WT_F02.14050.14050.2 0.00119 16-Nov K.IGLVEDLNK[136.11].G "sp|Q6KC79|NIPBL_HUMAN,tr|A0A590UJS4|A0A590UJS4_HUMAN" 2 1007.5743 1.21 14214 14050 2 1007.575442 504.7944 Nipped-B-like protein OS=Homo sapiens OX=9606 GN=NIPBL PE=1 SV=2 4.37 2836.6 - 1.90E+06 - - - 1.1721 - 2.359 0.327 - 253.4 1 2 0 0.0012 9 0 0 0 7.53E+07 6.22E+07 - - - 3.9388 0.9924 221125_WJC_METTL3_EV_vs_WT_F02.14052.14052.2 0.00329 14-Aug R.SEFTLMAK.R "sp|Q13190|STX5_HUMAN,tr|H7C3X5|H7C3X5_HUMAN,tr|E9PNU4|E9PNU4_HUMAN" 3 925.4579 0.99 14216 14052 2 925.453626 463.7362 Syntaxin-5 OS=Homo sapiens OX=9606 GN=STX5 PE=1 SV=2 5.72 2836.7 - 1.37E+06 - - - -4.6226 - 1.519 0.362 - 270.5 1 2 0 -0.0043 8 0 0 0 3.65E+07 3.69E+07 - - - 2.9742 0.9986 221125_WJC_METTL3_EV_vs_WT_F02.14053.14053.2 0.00746 20-Aug K.EAPPPVLLTPK.A sp|P48634|PRC2A_HUMAN 1 1160.6805 1.25 14217 14053 2 1160.680856 581.3475 Protein PRRC2A OS=Homo sapiens OX=9606 GN=PRRC2A PE=1 SV=3 6.1 2836.8 - 737164 - - - 0.2972 - 1.332 0.314 - 166 1 2 0 0.0003 11 0 0 0 9.77E+07 7.80E+07 - - - 2.1356 0.9999 221125_WJC_METTL3_EV_vs_WT_F02.14054.14054.2 2.28E-05 26-Dec R.LVPGGGATEIELAK[136.11].Q sp|P50990|TCPQ_HUMAN 1 1361.7646 0.42 14218 14054 2 1361.765771 681.8896 T-complex protein 1 subunit theta OS=Homo sapiens OX=9606 GN=CCT8 PE=1 SV=4 4.53 2837 - 579996 - - - 0.8739 - 2.223 0.541 - 347 1 2 0 0.0012 14 0 0 0 1.77E+09 4.24E+09 - - - 5.0411 0.9996 221125_WJC_METTL3_EV_vs_WT_F02.14061.14061.2 0.103 14/20 K.LAVLITNSNVR[166.11].H sp|P51570|GALK1_HUMAN 1 1208.7116 1.6 14223 14061 2 1208.711499 605.3631 Galactokinase OS=Homo sapiens OX=9606 GN=GALK1 PE=1 SV=1 9.75 2837.6 - 4.03E+06 - - - -0.1175 - 2.03 0.309 - 883.2 1 2 0 -0.0001 11 0 0 0 2.68E+08 1.68E+08 - - - 3.2386 0.9994 221125_WJC_METTL3_EV_vs_WT_F02.14062.14062.2 0.101 18-Aug R.FIVSPVPESR[166.11].L "sp|Q9H4A3|WNK1_HUMAN,tr|F5GWT4|F5GWT4_HUMAN,tr|A0A6Q8PFM0|A0A6Q8PFM0_HUMAN,tr|H0YH68|H0YH68_HUMAN" 4 1139.6214 1.66 14224 14062 2 1139.621681 570.818 Serine\threonine-protein kinase WNK1 OS=Homo sapiens OX=9606 GN=WNK1 PE=1 SV=2 6 2837.7 - 1.42E+06 - - - 0.2211 - 1.689 0.322 - 239.9 1 2 0 0.0003 10 0 0 0 1.65E+08 9.90E+07 - - - 2.8822 0.9997 221125_WJC_METTL3_EV_vs_WT_F02.14063.14063.2 0.00365 20-Sep K.ALNMAIPGGPK.F "sp|Q6P2Q9|PRP8_HUMAN,tr|I3L0J9|I3L0J9_HUMAN" 2 1067.5798 0.87 14225 14063 2 1067.579056 534.7972 Pre-mRNA-processing-splicing factor 8 OS=Homo sapiens OX=9606 GN=PRPF8 PE=1 SV=2 8.8 2837.8 - 876705 - - - -0.651 - 1.982 0.353 - 178.1 1 2 0 -0.0007 11 0 0 0 2.61E+07 3.00E+07 - - - 3.4987 0.9278 221125_WJC_METTL3_EV_vs_WT_F02.14064.14064.2 5.59E-05 14/24 K.VALSSETEVALAR[166.11].D "sp|P27816|MAP4_HUMAN,tr|E7EVA0|E7EVA0_HUMAN,tr|A0A804HKE7|A0A804HKE7_HUMAN" 3 1354.7332 1.16 14226 14064 2 1354.743168 678.3739 Microtubule-associated protein 4 OS=Homo sapiens OX=9606 GN=MAP4 PE=1 SV=3 4.53 2837.9 - 769594 - - - 7.3837 - 2.481 0.145 - 580.1 1 2 0 0.01 13 0 0 0 1.41E+07 1.21E+07 - - - 2.4409 0.9975 221125_WJC_METTL3_EV_vs_WT_F02.14070.14070.2 0.00324 16-Aug K.YLPALGYSK[136.11].R "sp|P54577|SYYC_HUMAN,tr|A0A6Q8PFX2|A0A6Q8PFX2_HUMAN" 2 1018.5579 0.61 14230 14070 2 1018.559803 510.2862 "Tyrosine--tRNA ligase, cytoplasmic OS=Homo sapiens OX=9606 GN=YARS1 PE=1 SV=4" 8.5 2838.6 - 5.49E+06 - - - 1.885 - 1.282 0.336 - 206.7 1 2 0 0.0019 9 0 0 0 9.40E+07 1.53E+08 - - - 2.2408 0.9643 221125_WJC_METTL3_EV_vs_WT_F02.14071.14071.2 0.00169 12-Jun N.SYFMDVK[136.11].C "sp|Q71UM5|RS27L_HUMAN,sp|P42677|RS27_HUMAN,tr|H0YMV8|H0YMV8_HUMAN,tr|C9JLI6|C9JLI6_HUMAN" 4 896.4193 0.39 14231 14071 2 896.418952 449.2169 40S ribosomal protein S27-like OS=Homo sapiens OX=9606 GN=RPS27L PE=1 SV=3 5.55 2838.7 - 4.20E+06 - - - -0.4328 - 1.266 0.412 - 129.9 1 1 0 -0.0004 7 0 0 0 4.56E+07 1.17E+08 - - - 2.8313 0.9999 221125_WJC_METTL3_EV_vs_WT_F02.14074.14074.2 3.78E-05 20-Nov K.IGEGTYGTVFK[136.11].A sp|Q00535|CDK5_HUMAN 1 1178.6063 0.49 14232 14074 2 1178.606621 590.3104 Cyclin-dependent-like kinase 5 OS=Homo sapiens OX=9606 GN=CDK5 PE=1 SV=3 6 2839.1 - 2.71E+06 - - - 0.2808 - 2.502 0.498 - 260.2 1 2 0 0.0003 11 0 0 0 3.20E+07 6.55E+07 - - - 5.2001 0.9936 221125_WJC_METTL3_EV_vs_WT_F02.14075.14075.2 0.0985 20-Oct K.QVVESAYEVIK.L sp|P00338|LDHA_HUMAN 1 1263.6711 0.55 14233 14075 2 1263.673076 632.8428 L-lactate dehydrogenase A chain OS=Homo sapiens OX=9606 GN=LDHA PE=1 SV=2 4.53 2839.2 - 833561 - - - 1.589 - 1.334 0.208 - 98.8 1 2 0 0.002 11 0 0 0 6.07E+06 1.09E+07 - - - 1.3563 0.9929 221125_WJC_METTL3_EV_vs_WT_F02.14076.14076.2 0.0153 18-Jul R.LWQTTEEIPK.R "sp|Q9BZE1|RM37_HUMAN,tr|S4R369|S4R369_HUMAN" 2 1243.6449 2.32 14234 14076 2 1243.649134 622.8297 "39S ribosomal protein L37, mitochondrial OS=Homo sapiens OX=9606 GN=MRPL37 PE=1 SV=2" 4.53 2839.3 - 306442 - - - 3.4423 - 1.416 0.305 - 144.1 1 2 0 0.0043 10 0 0 0 5.64E+06 2.43E+06 - - - 2.2633 0.9952 221125_WJC_METTL3_EV_vs_WT_F02.14080.14080.2 0.517 14-Aug K.IIQLIEGK[136.11].A "sp|O95861|BPNT1_HUMAN,tr|A6NF51|A6NF51_HUMAN" 2 920.5786 1.49 14236 14080 2 920.578027 461.2966 "3'(2'),5'-bisphosphate nucleotidase 1 OS=Homo sapiens OX=9606 GN=BPNT1 PE=1 SV=1" 6 2839.7 - 2.00E+06 - - - -0.642 - 1.408 0.149 - 183.6 1 2 0 -0.0006 8 0 0 0 5.65E+07 3.80E+07 - - - 1.1733 0.9987 221125_WJC_METTL3_EV_vs_WT_F02.14082.14082.2 0.0899 12-Jul K.FYVEDLK[136.11].A "sp|O75400|PR40A_HUMAN,tr|A0A7N4I394|A0A7N4I394_HUMAN" 2 920.4735 1.23 14238 14082 2 920.473155 461.244 Pre-mRNA-processing factor 40 homolog A OS=Homo sapiens OX=9606 GN=PRPF40A PE=1 SV=2 4.37 2840 - 2.00E+06 - - - -0.3574 - 1.33 0.3 - 141.2 1 2 0 -0.0003 7 0 0 0 5.80E+07 4.73E+07 - - - 2.1603 0.9998 221125_WJC_METTL3_EV_vs_WT_F02.14087.14087.2 0.000701 16-Oct R.VTELFMDNK.N "sp|P52732|KIF11_HUMAN,tr|A0A7I2YQY4|A0A7I2YQY4_HUMAN,tr|A0A7I2V3A9|A0A7I2V3A9_HUMAN,tr|A0A7I2V3V3|A0A7I2V3V3_HUMAN" 4 1095.527 3.57 14240 14087 2 1095.526823 548.7708 Kinesin-like protein KIF11 OS=Homo sapiens OX=9606 GN=KIF11 PE=1 SV=2 4.37 2840.6 - 7.83E+06 - - - -0.2036 - 2.175 0.385 - 541 1 2 0 -0.0002 9 0 0 0 1.84E+08 5.15E+07 - - - 4.1325 0.998 221125_WJC_METTL3_EV_vs_WT_F02.14093.14093.2 0.119 14-Jun K.FIINSYPK.Y "sp|Q96EY7|PTCD3_HUMAN,tr|B8ZZQ4|B8ZZQ4_HUMAN" 2 980.5331 1.19 14244 14093 2 980.534316 491.2738 "Pentatricopeptide repeat domain-containing protein 3, mitochondrial OS=Homo sapiens OX=9606 GN=PTCD3 PE=1 SV=3" 8.59 2841.2 - 2.17E+06 - - - 1.2218 - 1.187 0.344 - 115.3 1 2 0 0.0012 8 0 0 0 8.29E+07 6.94E+07 - - - 2.0984 0.9761 221125_WJC_METTL3_EV_vs_WT_F02.14094.14094.2 0.71 18-Aug K.GPLPAGTILK[136.11].L "sp|P51610|HCFC1_HUMAN,tr|A6NEM2|A6NEM2_HUMAN" 2 973.6052 0.78 14245 14094 2 973.603551 487.8099 Host cell factor 1 OS=Homo sapiens OX=9606 GN=HCFC1 PE=1 SV=2 8.75 2841.3 - 1.11E+06 - - - -1.6598 - 1.144 0.132 - 158.6 1 2 0 -0.0016 10 0 0 0 2.07E+07 2.67E+07 - - - 0.391 0.956 221125_WJC_METTL3_EV_vs_WT_F02.14095.14095.2 0.789 12-Jun R.HLQLAIR.N "sp|P16104|H2AX_HUMAN,sp|Q9BTM1|H2AJ_HUMAN,sp|Q93077|H2A1C_HUMAN,sp|Q99878|H2A1J_HUMAN,sp|Q16777|H2A2C_HUMAN,sp|Q96QV6|H2A1A_HUMAN,sp|P0C0S5|H2AZ_HUMAN,sp|P04908|H2A1B_HUMAN,sp|P20671|H2A1D_HUMAN,sp|P0C0S8|H2A1_HUMAN,sp|Q6FI13|H2A2A_HUMAN,sp|Q96KK5|H2A1H_HUMAN,sp|Q71UI9|H2AV_HUMAN,sp|Q7L7L0|H2A3_HUMAN,tr|C9J386|C9J386_HUMAN,tr|A0A0U1RR32|A0A0U1RR32_HUMAN,tr|A0A0U1RRH7|A0A0U1RRH7_HUMAN,tr|A0A3B3IS11|A0A3B3IS11_HUMAN,tr|H0YFX9|H0YFX9_HUMAN,tr|C9J0D1|C9J0D1_HUMAN,tr|A0A494C189|A0A494C189_HUMAN" 21 849.5185 0.61 14246 14095 2 849.519355 425.7665 Histone H2AX OS=Homo sapiens OX=9606 GN=H2AX PE=1 SV=2 9.76 2841.4 - 364484 - - - 1.0406 - 1.281 0.001 - 133.6 1 2 0 0.0009 7 0 0 0 7.32E+06 1.21E+07 - - - -0.1672 0.9993 221125_WJC_METTL3_EV_vs_WT_F02.14096.14096.2 0.00398 20-Sep K.QVVESAYEVIK[136.11].L sp|P00338|LDHA_HUMAN 1 1271.6853 0.55 14247 14096 2 1271.684213 636.8499 L-lactate dehydrogenase A chain OS=Homo sapiens OX=9606 GN=LDHA PE=1 SV=2 4.53 2841.5 - 209502 - - - -0.8296 - 1.603 0.332 - 129.4 1 2 0 -0.0011 11 0 0 0 6.07E+06 1.11E+07 - - - 2.7694 0.9987 221125_WJC_METTL3_EV_vs_WT_F02.14099.14099.2 0.0145 14-Aug R.DFTPAELR[166.11].R sp|O00264|PGRC1_HUMAN 1 957.4795 1.5 14249 14099 2 957.479327 479.747 Membrane-associated progesterone receptor component 1 OS=Homo sapiens OX=9606 GN=PGRMC1 PE=1 SV=3 4.37 2841.9 - 6.88E+06 - - - -0.1974 - 1.34 0.297 - 244.8 1 2 0 -0.0002 8 0 0 0 3.18E+08 2.13E+08 - - - 2.1173 0.9998 221125_WJC_METTL3_EV_vs_WT_F02.14102.14102.2 0.000601 14/20 R.ALC[160.03]MVC[160.03]GAEIR[166.11].A sp|Q9BUA3|SPNDC_HUMAN 1 1288.5966 2.32 14251 14102 2 1288.598147 645.3056 Spindlin interactor and repressor of chromatin-binding protein OS=Homo sapiens OX=9606 GN=SPINDOC PE=1 SV=3 6.03 2842.2 - 1.34E+06 - - - 1.2362 - 2.155 0.492 - 1004.3 1 2 0 0.0016 11 0 0 0 9.76E+07 4.21E+07 - - - 4.7515 0.9998 221125_WJC_METTL3_EV_vs_WT_F02.14103.14103.3 0.00186 Nov-52 R.LVPGGGATEIELAK[136.11].Q sp|P50990|TCPQ_HUMAN 1 1361.7646 0.39 14252 14103 3 1361.764818 454.9288 T-complex protein 1 subunit theta OS=Homo sapiens OX=9606 GN=CCT8 PE=1 SV=4 4.53 2842.2 - 1.72E+06 - - - 0.174 - 1.854 0.395 - 131.5 1 2 0 0.0002 14 0 0 0 8.14E+07 2.10E+08 - - - 4.5844 0.9998 221125_WJC_METTL3_EV_vs_WT_F02.14104.14104.2 0.00436 13/22 R.LIESSLGSIATK[136.11].F sp|O00443|P3C2A_HUMAN 1 1225.7009 1.07 14253 14104 2 1225.702359 613.8577 Phosphatidylinositol 4-phosphate 3-kinase C2 domain-containing subunit alpha OS=Homo sapiens OX=9606 GN=PIK3C2A PE=1 SV=2 6 2842.4 - 1.27E+06 - - - 1.1757 - 2.601 0.469 - 325.7 1 2 0 0.0014 12 0 0 0 8.24E+07 7.73E+07 - - - 5.0197 0.9996 221125_WJC_METTL3_EV_vs_WT_F02.14108.14108.2 0.00148 14-Aug R.DFTPAELR.R sp|O00264|PGRC1_HUMAN 1 947.4712 1.48 14255 14108 2 947.471431 474.7429 Membrane-associated progesterone receptor component 1 OS=Homo sapiens OX=9606 GN=PGRMC1 PE=1 SV=3 4.37 2842.8 - 4.88E+06 - - - 0.1953 - 1.882 0.312 - 285.1 1 2 0 0.0002 8 0 0 0 3.43E+08 2.32E+08 - - - 3.2525 0.9999 221125_WJC_METTL3_EV_vs_WT_F02.14109.14109.2 0.0235 22-Dec R.LIESSLGSIATK.F sp|O00443|P3C2A_HUMAN 1 1217.6867 1.07 14256 14109 2 1217.68749 609.8506 Phosphatidylinositol 4-phosphate 3-kinase C2 domain-containing subunit alpha OS=Homo sapiens OX=9606 GN=PIK3C2A PE=1 SV=2 6 2842.8 - 2.03E+06 - - - 0.634 - 2.393 0.49 - 373.2 1 2 0 0.0008 12 0 0 0 8.24E+07 7.73E+07 - - - 4.9557 0.9993 221125_WJC_METTL3_EV_vs_WT_F02.14110.14110.2 0.0132 14-Jul K.SAFAPFGK.L "sp|Q01085|TIAR_HUMAN,tr|E7ETC0|E7ETC0_HUMAN,tr|A6NKZ9|A6NKZ9_HUMAN,tr|E7ETJ9|E7ETJ9_HUMAN" 4 823.4228 0.93 14257 14110 2 823.423975 412.7187 Nucleolysin TIAR OS=Homo sapiens OX=9606 GN=TIAL1 PE=1 SV=1 8.47 2842.9 - 6.73E+06 - - - 1.3796 - 1.656 0.346 - 201.9 1 2 0 0.0011 8 0 0 0 1.84E+08 1.98E+08 - - - 3.1175 0.9998 221125_WJC_METTL3_EV_vs_WT_F02.14112.14112.2 4.74E-05 16-Sep R.VLDELTLTK.A "sp|P13645|K1C10_HUMAN,tr|A0A1B0GVI3|A0A1B0GVI3_HUMAN" 2 1030.591 35.31 14259 14112 2 1030.592133 516.3028 "Keratin, type I cytoskeletal 10 OS=Homo sapiens OX=9606 GN=KRT10 PE=1 SV=6" 4.37 2843.1 - 804846 - - - 1.0732 - 2.004 0.431 - 208.4 1 2 0 0.0011 9 0 0 0 3.97E+07 1.12E+06 - - - 4.2351 0.9998 221125_WJC_METTL3_EV_vs_WT_F02.14114.14114.2 1.32E-07 13/26 K.LAPALATGNTVVMK[136.11].V sp|P30837|AL1B1_HUMAN 1 1392.789 1.03 14261 14114 2 1392.79159 697.4018 "Aldehyde dehydrogenase X, mitochondrial OS=Homo sapiens OX=9606 GN=ALDH1B1 PE=1 SV=3" 8.75 2843.3 - 323503 - - - 1.8438 - 2.686 0.559 - 515.5 1 2 0 0.0026 14 0 0 0 1.99E+07 1.93E+07 - - - 5.6484 0.9997 221125_WJC_METTL3_EV_vs_WT_F02.14116.14116.2 0.317 18-Dec R.ISGLIYEETR[166.11].G sp|P62805|H4_HUMAN 1 1189.6218 2.15 14262 14116 2 1189.622104 595.8182 Histone H4 OS=Homo sapiens OX=9606 GN=H4C1 PE=1 SV=2 4.53 2843.5 - 403929 - - - 0.2362 - 2.522 0.292 - 525.8 1 2 0 0.0003 10 0 0 0 4.16E+07 1.94E+07 - - - 3.7797 0.9997 221125_WJC_METTL3_EV_vs_WT_F02.14118.14118.3 9.96E-05 Oct-32 K.LVKEEVFWR.N sp|Q96A49|SYAP1_HUMAN 1 1204.6604 1.18 14263 14118 3 1204.660533 402.5608 Synapse-associated protein 1 OS=Homo sapiens OX=9606 GN=SYAP1 PE=1 SV=1 6.14 2843.8 - 4.78E+06 - - - 0.0739 - 2.109 0.421 - 154.5 1 2 1 0.0001 9 0 0 0 8.94E+08 7.59E+08 - - - 5.4826 0.9984 221125_WJC_METTL3_EV_vs_WT_F02.14119.14119.2 0.0204 14-Aug K.TWTTADFR.T "sp|Q9ULX6|AKP8L_HUMAN,tr|A0A7P0T9N5|A0A7P0T9N5_HUMAN,tr|A0A7P0TAD3|A0A7P0TAD3_HUMAN,tr|V9GZ50|V9GZ50_HUMAN,tr|A0A7P0TBP0|A0A7P0TBP0_HUMAN,tr|A0A7P0TAJ5|A0A7P0TAJ5_HUMAN,tr|A0A7P0TAE3|A0A7P0TAE3_HUMAN,tr|A0A7P0T847|A0A7P0T847_HUMAN" 8 996.4665 0.87 14264 14119 2 996.466409 499.2405 A-kinase anchor protein 8-like OS=Homo sapiens OX=9606 GN=AKAP8L PE=1 SV=4 5.5 2843.8 - 2.31E+06 - - - -0.0863 - 1.264 0.302 - 308.9 1 2 0 -0.0001 8 0 0 0 7.39E+07 8.48E+07 - - - 1.9781 0.9997 221125_WJC_METTL3_EV_vs_WT_F02.14120.14120.2 0.00233 18-Oct R.VNC[160.03]LAPGLIK.T "sp|P0CG22|DR4L1_HUMAN,sp|Q9BTZ2|DHRS4_HUMAN,tr|H0YNP7|H0YNP7_HUMAN" 3 1083.6111 1.38 14265 14120 2 1083.611443 542.8128 Putative dehydrogenase\reductase SDR family member 4-like 1 OS=Homo sapiens OX=9606 GN=DHRS4L1 PE=5 SV=1 8.19 2843.9 - 2.40E+06 - - - 0.3618 - 1.989 0.374 - 267.8 1 2 0 0.0004 10 0 0 0 6.94E+08 5.04E+08 - - - 3.7226 0.8464 221125_WJC_METTL3_EV_vs_WT_F02.14121.14121.2 0.288 22-Sep R.MIPTVAANIHPS.G sp|Q92922|SMRC1_HUMAN 1 1249.6489 - 14266 14121 2 1249.645528 625.8317 SWI\SNF complex subunit SMARCC1 OS=Homo sapiens OX=9606 GN=SMARCC1 PE=1 SV=3 6.49 2844 - 772908 - - - -2.6928 - 1.794 0.263 - 256.1 1 1 0 -0.0034 12 0 0 0 - - - - - 2.5202 0.9919 221125_WJC_METTL3_EV_vs_WT_F02.14126.14126.2 0.0249 12-Jul K.VLEIPYK.G "sp|P48594|SPB4_HUMAN,sp|P29508|SPB3_HUMAN,tr|C9JZ65|C9JZ65_HUMAN,tr|H0Y5H9|H0Y5H9_HUMAN" 4 860.5008 404.4 14269 14126 2 860.50085 431.2577 Serpin B4 OS=Homo sapiens OX=9606 GN=SERPINB4 PE=1 SV=2 5.97 2844.6 - 1.38E+07 - - - 0.1104 - 1.426 0.081 - 219.4 1 2 0 0.0001 7 0 0 0 3.97E+08 9.82E+05 - - - 0.7637 0.9977 221125_WJC_METTL3_EV_vs_WT_F02.14127.14127.2 0.0643 14-Jun K.TWTTADFR[166.11].T "sp|Q9ULX6|AKP8L_HUMAN,tr|A0A7P0T9N5|A0A7P0T9N5_HUMAN,tr|A0A7P0TAD3|A0A7P0TAD3_HUMAN,tr|V9GZ50|V9GZ50_HUMAN,tr|A0A7P0TBP0|A0A7P0TBP0_HUMAN,tr|A0A7P0TAJ5|A0A7P0TAJ5_HUMAN,tr|A0A7P0TAE3|A0A7P0TAE3_HUMAN,tr|A0A7P0T847|A0A7P0T847_HUMAN" 8 1006.4748 0.87 14270 14127 2 1006.474823 504.2447 A-kinase anchor protein 8-like OS=Homo sapiens OX=9606 GN=AKAP8L PE=1 SV=4 5.5 2844.7 - 3.96E+06 - - - 0.0576 - 1.388 0.224 - 171.3 1 2 0 0.0001 8 0 0 0 7.39E+07 8.52E+07 - - - 1.6843 0.9957 221125_WJC_METTL3_EV_vs_WT_F02.14128.14128.2 1.04 18-Oct R.QVLLGDQIPK[136.11].F sp|P28072|PSB6_HUMAN 1 1117.6587 0.66 14271 14128 2 1117.656763 559.8366 Proteasome subunit beta type-6 OS=Homo sapiens OX=9606 GN=PSMB6 PE=1 SV=4 5.84 2844.7 - 2.42E+06 - - - -1.6964 - 1.641 0.163 - 277.2 1 2 0 -0.0019 10 0 0 0 1.03E+08 1.57E+08 - - - 1.6269 0.999 221125_WJC_METTL3_EV_vs_WT_F02.14129.14129.2 0.0105 18-Sep R.LGLMPPPEPK.V sp|O43395|PRPF3_HUMAN 1 1077.5893 2.08 14272 14129 2 1077.590348 539.8019 U4\U6 small nuclear ribonucleoprotein Prp3 OS=Homo sapiens OX=9606 GN=PRPF3 PE=1 SV=2 6 2844.8 - 2.40E+06 - - - 1.0162 - 1.799 0.265 - 216.3 1 2 0 0.0011 10 0 0 0 6.58E+07 3.16E+07 - - - 2.6371 0.9969 221125_WJC_METTL3_EV_vs_WT_F02.14130.14130.2 0.0154 14-Aug K.WLVETQVK.A "sp|Q9BSJ6|PIMRE_HUMAN,tr|I3L156|I3L156_HUMAN,tr|I3L419|I3L419_HUMAN,tr|I3L2R2|I3L2R2_HUMAN" 4 1001.5546 1.1 14273 14130 2 1001.555826 501.7846 Protein PIMREG OS=Homo sapiens OX=9606 GN=PIMREG PE=1 SV=1 6 2844.8 - 2.40E+06 - - - 1.2421 - 1.405 0.229 - 144 1 2 0 0.0012 8 0 0 0 5.20E+07 4.74E+07 - - - 1.7575 0.9973 221125_WJC_METTL3_EV_vs_WT_F02.14133.14133.2 0.0201 18-Jul M.GLVC[160.03]VLGDGK[136.11].T tr|Q5RI18|Q5RI18_HUMAN 1 1024.5467 2.74 14276 14133 2 1024.548904 513.2806 Heterogeneous nuclear ribonucleoprotein U OS=Homo sapiens OX=9606 GN=HNRNPU PE=1 SV=9 5.83 2845.1 - 909840 - - - 2.1844 - 1.569 0.276 - 143.4 1 2 0 0.0022 10 0 0 0 1.57E+08 5.73E+07 - - - 2.3361 0.9998 221125_WJC_METTL3_EV_vs_WT_F02.14134.14134.2 6.02E-06 15/26 K.LAPALATGNTVVMK.V sp|P30837|AL1B1_HUMAN 1 1384.7748 1.03 14277 14134 2 1384.777197 693.3947 "Aldehyde dehydrogenase X, mitochondrial OS=Homo sapiens OX=9606 GN=ALDH1B1 PE=1 SV=3" 8.75 2845.3 - 818156 - - - 1.7151 - 2.736 0.529 - 688.8 1 2 0 0.0024 14 0 0 0 1.99E+07 1.93E+07 - - - 5.4732 0.9999 221125_WJC_METTL3_EV_vs_WT_F02.14136.14136.2 1.38E-05 24-Nov K.VLGC[160.03]PEALTGSYK[136.11].S "sp|Q14181|DPOA2_HUMAN,tr|A0A3B3ITS5|A0A3B3ITS5_HUMAN" 2 1401.7054 0.61 14279 14136 2 1401.703993 701.86 DNA polymerase alpha subunit B OS=Homo sapiens OX=9606 GN=POLA2 PE=1 SV=2 5.96 2845.5 - 437369 - - - -0.9695 - 2.227 0.56 - 305.5 1 2 0 -0.0014 13 0 0 0 8.19E+06 1.33E+07 - - - 5.2316 0.9998 221125_WJC_METTL3_EV_vs_WT_F02.14139.14139.3 0.000184 Nov-32 K.LVK[136.11]EEVFWR[166.11].N sp|Q96A49|SYAP1_HUMAN 1 1222.6829 1.18 14280 14139 3 1222.682405 408.5682 Synapse-associated protein 1 OS=Homo sapiens OX=9606 GN=SYAP1 PE=1 SV=1 6.14 2845.9 - 1.86E+07 - - - -0.4163 - 2.197 0.445 - 249.5 1 2 1 -0.0005 9 0 0 0 8.91E+08 7.55E+08 - - - 5.8733 0.9999 221125_WJC_METTL3_EV_vs_WT_F02.14141.14141.2 4.07E-05 20-Dec K.VAASVLNPYVK.R "sp|P48047|ATPO_HUMAN,tr|H7C0C1|H7C0C1_HUMAN,tr|A0A494C0K9|A0A494C0K9_HUMAN" 3 1159.6601 1 14282 14141 2 1159.660757 580.8373 "ATP synthase subunit O, mitochondrial OS=Homo sapiens OX=9606 GN=ATP5PO PE=1 SV=1" 8.56 2846 - 1.04E+07 - - - 0.5579 - 2.53 0.453 - 519.4 1 2 0 0.0006 11 0 0 0 7.12E+08 7.09E+08 - - - 4.8977 0.9999 221125_WJC_METTL3_EV_vs_WT_F02.14142.14142.2 1.12E-07 18-Nov R.VNC[160.03]LAPGLIK[136.11].T "sp|P0CG22|DR4L1_HUMAN,sp|Q9BTZ2|DHRS4_HUMAN,tr|H0YNP7|H0YNP7_HUMAN" 3 1091.6253 1.38 14283 14142 2 1091.624803 546.8199 Putative dehydrogenase\reductase SDR family member 4-like 1 OS=Homo sapiens OX=9606 GN=DHRS4L1 PE=5 SV=1 8.19 2846 - 7.57E+06 - - - -0.4104 - 2.388 0.506 - 563.1 1 2 0 -0.0004 10 0 0 0 6.94E+08 5.04E+08 - - - 5.2079 0.9995 221125_WJC_METTL3_EV_vs_WT_F02.14143.14143.2 0.00795 14-Sep R.VLDLQQIK[136.11].G "sp|Q9UNM6|PSD13_HUMAN,tr|J3KNQ3|J3KNQ3_HUMAN" 2 963.5844 0.54 14284 14143 2 963.583746 482.7995 26S proteasome non-ATPase regulatory subunit 13 OS=Homo sapiens OX=9606 GN=PSMD13 PE=1 SV=2 5.81 2846.1 - 5.20E+06 - - - -0.7119 - 1.518 0.39 - 188 1 2 0 -0.0007 8 0 0 0 9.37E+07 1.73E+08 - - - 3.1802 0.9841 221125_WJC_METTL3_EV_vs_WT_F02.14144.14144.2 0.0665 16-Aug K.LVKEEVFWR.N sp|Q96A49|SYAP1_HUMAN 1 1204.6604 1.19 14285 14144 2 1204.660187 603.3375 Synapse-associated protein 1 OS=Homo sapiens OX=9606 GN=SYAP1 PE=1 SV=1 6.14 2846.1 - 2.38E+06 - - - -0.2133 - 1.498 0.25 - 198.4 1 2 1 -0.0003 9 0 0 0 1.56E+08 1.31E+08 - - - 2.0566 0.9996 221125_WJC_METTL3_EV_vs_WT_F02.14145.14145.2 0.00256 18-Nov R.QVLLGDQIPK.F sp|P28072|PSB6_HUMAN 1 1109.6445 0.66 14286 14145 2 1109.644896 555.8295 Proteasome subunit beta type-6 OS=Homo sapiens OX=9606 GN=PSMB6 PE=1 SV=4 5.84 2846.2 - 1.72E+06 - - - 0.3938 - 1.822 0.372 - 375.5 1 2 0 0.0004 10 0 0 0 1.03E+08 1.57E+08 - - - 3.4631 0.9998 221125_WJC_METTL3_EV_vs_WT_F02.14150.14150.2 0.00919 14-Aug K.SAFAPFGK[136.11].L "sp|Q01085|TIAR_HUMAN,tr|E7ETC0|E7ETC0_HUMAN,tr|A6NKZ9|A6NKZ9_HUMAN,tr|E7ETJ9|E7ETJ9_HUMAN" 4 831.437 1.7 14290 14150 2 831.436664 416.7258 Nucleolysin TIAR OS=Homo sapiens OX=9606 GN=TIAL1 PE=1 SV=1 8.47 2846.7 - 2.56E+06 - - - -0.451 - 1.818 0.408 - 271.1 1 2 0 -0.0004 8 0 0 0 1.55E+08 9.13E+07 - - - 3.8571 0.891 221125_WJC_METTL3_EV_vs_WT_F02.14154.14154.2 0.15 20-Jul F.ATPEQISMDLK.N sp|Q08211|DHX9_HUMAN 1 1231.6118 1.3 14294 14154 2 1231.61243 616.8132 ATP-dependent RNA helicase A OS=Homo sapiens OX=9606 GN=DHX9 PE=1 SV=4 4.37 2847 - 300984 - - - 0.4799 - 1.408 0.254 - 104.7 1 1 0 0.0006 11 0 0 0 6.85E+06 5.26E+06 - - - 1.8425 0.9955 221125_WJC_METTL3_EV_vs_WT_F02.14157.14157.2 0.00208 16-Aug K.LVK[136.11]EEVFWR[166.11].N sp|Q96A49|SYAP1_HUMAN 1 1222.6829 1.19 14295 14157 2 1222.68381 612.3487 Synapse-associated protein 1 OS=Homo sapiens OX=9606 GN=SYAP1 PE=1 SV=1 6.14 2847.4 - 4.34E+06 - - - 0.7328 - 1.644 0.399 - 249.2 1 2 1 0.0009 9 0 0 0 1.56E+08 1.31E+08 - - - 3.426 0.9998 221125_WJC_METTL3_EV_vs_WT_F02.14158.14158.2 0.000364 14-Jul R.GYDVDFPR[166.11].N "sp|Q06210|GFPT1_HUMAN,sp|O94808|GFPT2_HUMAN,tr|A0A6I8PRN4|A0A6I8PRN4_HUMAN,tr|A0A6I8PTT9|A0A6I8PTT9_HUMAN" 4 977.4482 1 14296 14158 2 977.448316 489.7314 Glutamine--fructose-6-phosphate aminotransferase [isomerizing] 1 OS=Homo sapiens OX=9606 GN=GFPT1 PE=1 SV=3 4.21 2847.5 - 1.08E+06 - - - 0.1023 - 1.473 0.566 - 173.6 1 2 0 0.0001 8 0 0 0 4.31E+07 4.30E+07 - - - 4.3895 0.9997 221125_WJC_METTL3_EV_vs_WT_F02.14159.14159.2 0.0291 16-Aug K.EVAGLVTLK[136.11].H sp|Q9Y3B7|RM11_HUMAN 1 936.5735 0.99 14297 14159 2 936.573387 469.294 "39S ribosomal protein L11, mitochondrial OS=Homo sapiens OX=9606 GN=MRPL11 PE=1 SV=1" 6.1 2847.5 - 1.67E+06 - - - -0.1559 - 1.861 0.347 - 234.3 1 2 0 -0.0001 9 0 0 0 5.28E+07 5.33E+07 - - - 3.4008 0.9997 221125_WJC_METTL3_EV_vs_WT_F02.14163.14163.2 8.37E-05 20-Dec K.VAASVLNPYVK[136.11].R "sp|P48047|ATPO_HUMAN,tr|H7C0C1|H7C0C1_HUMAN,tr|A0A494C0K9|A0A494C0K9_HUMAN" 3 1167.6743 1 14299 14163 2 1167.673916 584.8444 "ATP synthase subunit O, mitochondrial OS=Homo sapiens OX=9606 GN=ATP5PO PE=1 SV=1" 8.56 2848.1 - 2.45E+07 - - - -0.3374 - 2.447 0.302 - 551 1 2 0 -0.0004 11 0 0 0 7.12E+08 7.09E+08 - - - 3.6923 0.9908 221125_WJC_METTL3_EV_vs_WT_F02.14164.14164.2 0.161 16-Sep R.TFLAQHASL.- sp|Q9NPA8|ENY2_HUMAN 1 986.5185 - 14300 14164 2 986.519382 494.2665 Transcription and mRNA export factor ENY2 OS=Homo sapiens OX=9606 GN=ENY2 PE=1 SV=1 6.4 2848.1 - 2.06E+06 - - - 0.8626 - 1.16 0.183 - 153.7 1 2 0 0.0009 9 0 0 0 - - - - - 0.8218 0.9995 221125_WJC_METTL3_EV_vs_WT_F02.14166.14166.2 0.00312 14-Jun K.EC[160.03]ADLWPR[166.11].L "sp|P62829|RL23_HUMAN,tr|J3KTJ3|J3KTJ3_HUMAN" 2 1055.4734 0.91 14302 14166 2 1055.474528 528.744 60S ribosomal protein L23 OS=Homo sapiens OX=9606 GN=RPL23 PE=1 SV=1 4.37 2848.4 - 699950 - - - 1.0829 - 1.482 0.435 - 197.8 1 2 0 0.0011 8 0 0 0 2.15E+08 2.37E+08 - - - 3.44 0.998 221125_WJC_METTL3_EV_vs_WT_F02.14167.14167.2 0.0698 12-May R.GFLAEMK.R "sp|A6ZKI3|RTL8C_HUMAN,sp|Q9BWD3|RTL8A_HUMAN,sp|Q17RB0|RTL8B_HUMAN" 3 794.3997 1.09 14303 14167 2 794.399462 398.2071 Retrotransposon Gag-like protein 8C OS=Homo sapiens OX=9606 GN=RTL8C PE=1 SV=1 6 2848.5 - 602113 - - - -0.2505 - 1.215 0.286 - 88.4 1 2 0 -0.0002 7 0 0 0 9.21E+06 8.43E+06 - - - 1.7704 0.9657 221125_WJC_METTL3_EV_vs_WT_F02.14168.14168.2 0.0279 18-Oct R.IVELLNETEK.Y "sp|Q99996|AKAP9_HUMAN,tr|A0A0A0MRF6|A0A0A0MRF6_HUMAN,tr|A0A7P0TBH8|A0A7P0TBH8_HUMAN,tr|A0A7P0TAX3|A0A7P0TAX3_HUMAN,tr|A0A7P0T9A9|A0A7P0T9A9_HUMAN,tr|A0A7P0T8N5|A0A7P0T8N5_HUMAN,tr|A0A2R8Y590|A0A2R8Y590_HUMAN,tr|A0A7P0TBI4|A0A7P0TBI4_HUMAN,tr|A0A7P0Z4Q5|A0A7P0Z4Q5_HUMAN,tr|A0A7P0Z4N5|A0A7P0Z4N5_HUMAN,tr|A0A7P0TAD6|A0A7P0TAD6_HUMAN,tr|A0A7P0T939|A0A7P0T939_HUMAN,tr|A0A7P0T928|A0A7P0T928_HUMAN" 13 1186.6445 0.52 14304 14168 2 1186.635967 594.3295 A-kinase anchor protein 9 OS=Homo sapiens OX=9606 GN=AKAP9 PE=1 SV=4 4.25 2848.6 - 382493 - - - -7.2069 - 1.833 0.338 - 218.3 1 2 0 -0.0086 10 0 0 0 6.80E+06 1.32E+07 - - - 3.2262 0.9999 221125_WJC_METTL3_EV_vs_WT_F02.14172.14172.2 0.000207 18-Nov R.VLSTPDLEVR[166.11].K "sp|P53618|COPB_HUMAN,tr|E9PP73|E9PP73_HUMAN" 2 1137.6269 0.54 14306 14172 2 1137.626534 569.8207 Coatomer subunit beta OS=Homo sapiens OX=9606 GN=COPB1 PE=1 SV=3 4.37 2849.1 - 2.21E+06 - - - -0.3296 - 2.056 0.473 - 464.6 1 2 0 -0.0004 10 0 0 0 4.44E+07 8.24E+07 - - - 4.5463 0.9527 221125_WJC_METTL3_EV_vs_WT_F02.14174.14174.2 0.353 16-Jul K.LNPGFDLAK.G "sp|Q9UM63|PLAL1_HUMAN,tr|Q68DN7|Q68DN7_HUMAN" 2 973.5233 0.61 14308 14174 2 973.52491 487.7689 Zinc finger protein PLAGL1 OS=Homo sapiens OX=9606 GN=PLAGL1 PE=1 SV=2 5.84 2849.2 - 1.32E+06 - - - 1.6723 - 1.052 0.11 - 94 1 2 0 0.0016 9 0 0 0 3.84E+07 6.34E+07 - - - -0.0004 0.9989 221125_WJC_METTL3_EV_vs_WT_F02.14175.14175.2 0.00966 14-Jul R.AIYDIYGK[136.11].R "sp|Q9NVH1|DJC11_HUMAN,tr|Q5TH61|Q5TH61_HUMAN,tr|B1AK20|B1AK20_HUMAN" 3 949.5 0.58 14309 14175 2 949.500858 475.7573 DnaJ homolog subfamily C member 11 OS=Homo sapiens OX=9606 GN=DNAJC11 PE=1 SV=2 5.88 2849.3 - 1.10E+06 - - - 0.8678 - 1.461 0.307 - 138 1 2 0 0.0008 8 0 0 0 1.50E+07 2.59E+07 - - - 2.4517 1 221125_WJC_METTL3_EV_vs_WT_F02.14176.14176.2 5.06E-07 18-Dec R.LGDLYEEEMR.E "sp|P08670|VIME_HUMAN,tr|B0YJC4|B0YJC4_HUMAN" 2 1253.5598 1.88 14310 14176 2 1253.559526 627.7872 Vimentin OS=Homo sapiens OX=9606 GN=VIM PE=1 SV=4 4 2849.4 - 861543 - - - -0.221 - 2.576 0.576 - 617.2 1 2 0 -0.0003 10 0 0 0 4.58E+09 2.43E+09 - - - 5.9365 0.9998 221125_WJC_METTL3_EV_vs_WT_F02.14179.14179.2 0.000119 22-Nov R.TIAMDGTEGLVR[166.11].G "sp|P06576|ATPB_HUMAN,tr|F8W079|F8W079_HUMAN,tr|H0YH81|H0YH81_HUMAN" 3 1271.6419 1.51 14311 14179 2 1271.642491 636.8282 "ATP synthase subunit beta, mitochondrial OS=Homo sapiens OX=9606 GN=ATP5F1B PE=1 SV=3" 4.37 2849.8 - 4.17E+06 - - - 0.4592 - 1.758 0.49 - 262 1 2 0 0.0006 12 0 0 0 6.79E+08 4.50E+08 - - - 4.1444 0.9953 221125_WJC_METTL3_EV_vs_WT_F02.14180.14180.2 0.0173 20-Oct R.ATVNTFGYIAK.A "sp|O75533|SF3B1_HUMAN,tr|H7C341|H7C341_HUMAN" 2 1183.6237 2.12 14312 14180 2 1183.623564 592.8191 Splicing factor 3B subunit 1 OS=Homo sapiens OX=9606 GN=SF3B1 PE=1 SV=3 8.63 2849.9 - 962647 - - - -0.1352 - 1.947 0.04 - 321.3 1 2 0 -0.0002 11 0 0 0 4.49E+07 2.12E+07 - - - 1.1389 0.9779 221125_WJC_METTL3_EV_vs_WT_F02.14184.14184.2 0.317 12-Jun K.TLIEELK[136.11].A "sp|P16220|CREB1_HUMAN,sp|Q6QEF8|CORO6_HUMAN,sp|P18846|ATF1_HUMAN,tr|G5E998|G5E998_HUMAN,tr|E9PAR2|E9PAR2_HUMAN,tr|J3KSS5|J3KSS5_HUMAN,tr|J3QLV6|J3QLV6_HUMAN" 7 852.5048 0.63 14315 14184 2 852.504377 427.2597 Cyclic AMP-responsive element-binding protein 1 OS=Homo sapiens OX=9606 GN=CREB1 PE=1 SV=3 4.53 2850.4 - 3.28E+06 - - - -0.4786 - 1.246 0.05 - 121 1 2 0 -0.0004 7 0 0 0 3.93E+07 6.20E+07 - - - 0.1071 0.9986 221125_WJC_METTL3_EV_vs_WT_F02.14186.14186.2 0.0157 14-Jul K.GSFGEVFK[136.11].G "sp|Q9P289|STK26_HUMAN,sp|Q9Y6E0|STK24_HUMAN,tr|B4E0Y9|B4E0Y9_HUMAN,tr|B4DR80|B4DR80_HUMAN,tr|Q8NBY1|Q8NBY1_HUMAN" 5 877.4425 0.92 14316 14186 2 877.442628 439.7285 Serine\threonine-protein kinase 26 OS=Homo sapiens OX=9606 GN=STK26 PE=1 SV=2 6 2850.6 - 1.37E+06 - - - 0.1242 - 1.348 0.288 - 146.3 1 2 0 0.0001 8 0 0 0 2.64E+07 2.86E+07 - - - 2.0688 0.8468 221125_WJC_METTL3_EV_vs_WT_F02.14188.14188.2 3.97 12-Jul A.ALELLPR.E "sp|P78395|PRAME_HUMAN,sp|Q99832|TCPH_HUMAN,tr|E7EMH2|E7EMH2_HUMAN,tr|A0A0G2JRX8|A0A0G2JRX8_HUMAN,tr|B5MD04|B5MD04_HUMAN,tr|A0A0G2JRX7|A0A0G2JRX7_HUMAN,tr|H7C2P3|H7C2P3_HUMAN,tr|B5MCY4|B5MCY4_HUMAN,tr|E7EW99|E7EW99_HUMAN" 9 810.4963 0.17 14317 14188 2 810.496529 406.2554 Melanoma antigen preferentially expressed in tumors OS=Homo sapiens OX=9606 GN=PRAME PE=1 SV=1 6.05 2850.8 - 4.24E+06 - - - 0.2344 - 1.474 0.166 - 218.3 1 1 0 0.0002 7 0 0 0 7.74E+07 4.54E+08 - - - 1.4964 0.9998 221125_WJC_METTL3_EV_vs_WT_F02.14189.14189.2 0.00167 18-Sep R.VWDVESGSLK[136.11].S sp|Q9GZL7|WDR12_HUMAN 1 1126.575 1.52 14318 14189 2 1126.575381 564.2948 Ribosome biogenesis protein WDR12 OS=Homo sapiens OX=9606 GN=WDR12 PE=1 SV=2 4.37 2850.9 - 1.84E+06 - - - 0.348 - 1.89 0.439 - 272.4 1 2 0 0.0004 10 0 0 0 5.79E+07 3.81E+07 - - - 4.0602 0.9991 221125_WJC_METTL3_EV_vs_WT_F02.14191.14191.2 0.0269 14-Jul K.MLEQLDMR[166.11].R "sp|Q13838|DX39B_HUMAN,sp|O00148|DX39A_HUMAN,tr|K7EPJ3|K7EPJ3_HUMAN,tr|A0A140TA18|A0A140TA18_HUMAN,tr|F6UJC5|F6UJC5_HUMAN,tr|F6TRA5|F6TRA5_HUMAN,tr|F6WLT2|F6WLT2_HUMAN,tr|Q5STU3|Q5STU3_HUMAN,tr|A0A140T973|A0A140T973_HUMAN,tr|A0A140T9X9|A0A140T9X9_HUMAN,tr|A0A140T996|A0A140T996_HUMAN,tr|A0A140T9L4|A0A140T9L4_HUMAN,tr|A0A0G2JJZ9|A0A0G2JJZ9_HUMAN,tr|A0A140T9K1|A0A140T9K1_HUMAN,tr|K7EQN7|K7EQN7_HUMAN,tr|A0A140T9X3|A0A140T9X3_HUMAN,tr|F6S4E6|F6S4E6_HUMAN,tr|A0A0A0MT12|A0A0A0MT12_HUMAN" 18 1044.4972 0.91 14320 14191 2 1044.497561 523.2559 Spliceosome RNA helicase DDX39B OS=Homo sapiens OX=9606 GN=DDX39B PE=1 SV=1 4.37 2851 - 1.86E+06 - - - 0.3868 - 1.506 0.308 - 225.2 1 2 0 0.0004 8 0 0 0 5.19E+07 5.69E+07 - - - 2.5507 0.934 221125_WJC_METTL3_EV_vs_WT_F02.14192.14192.2 6.39 12-May K.QLELEIK[136.11].N "sp|Q92828|COR2A_HUMAN,sp|Q9UQN3|CHM2B_HUMAN,tr|C9J0A7|C9J0A7_HUMAN,tr|A0A087WW88|A0A087WW88_HUMAN" 4 879.5157 0.58 14321 14192 2 879.515139 440.7651 Coronin-2A OS=Homo sapiens OX=9606 GN=CORO2A PE=1 SV=2 4.53 2851.1 - 1.47E+06 - - - -0.6197 - 1.092 0.055 - 72 5 2 0 -0.0005 7 0 0 0 7.76E+06 1.35E+07 - - - -0.5863 0.9991 221125_WJC_METTL3_EV_vs_WT_F02.14193.14193.2 0.00397 16-Sep R.ETASELLMR.L "sp|Q01082|SPTB2_HUMAN,tr|A0A087WUZ3|A0A087WUZ3_HUMAN" 2 1048.5223 2.13 14322 14193 2 1048.521164 525.2684 "Spectrin beta chain, non-erythrocytic 1 OS=Homo sapiens OX=9606 GN=SPTBN1 PE=1 SV=2" 4.53 2851.2 - 1.25E+06 - - - -1.0787 - 1.802 0.266 - 284.1 1 2 0 -0.0011 9 0 0 0 4.81E+07 2.26E+07 - - - 2.709 0.9999 221125_WJC_METTL3_EV_vs_WT_F02.14197.14197.2 0.000478 18-Nov M.GLVC[160.03]VLGDGK.T tr|Q5RI18|Q5RI18_HUMAN 1 1016.5325 1.71 14325 14197 2 1016.532626 509.2735 Heterogeneous nuclear ribonucleoprotein U OS=Homo sapiens OX=9606 GN=HNRNPU PE=1 SV=9 5.83 2851.7 - 5.26E+06 - - - 0.1574 - 2.13 0.471 - 513.1 1 2 0 0.0002 10 0 0 0 9.30E+07 5.43E+07 - - - 4.6303 0.9965 221125_WJC_METTL3_EV_vs_WT_F02.14199.14199.2 0.00153 16-Aug K.YYTLEEIQK[136.11].H sp|P00167|CYB5_HUMAN 1 1193.606 1.28 14326 14199 2 1193.600938 597.8103 Cytochrome b5 OS=Homo sapiens OX=9606 GN=CYB5A PE=1 SV=2 4.53 2851.9 - 1.33E+06 - - - -4.2032 - 1.509 0.44 - 153 1 2 0 -0.005 9 0 0 0 4.91E+07 3.84E+07 - - - 3.4796 1 221125_WJC_METTL3_EV_vs_WT_F02.14200.14200.2 1.08E-07 20-Nov R.LVLDTVNEVSR.A "sp|Q9UPN3|MACF1_HUMAN,tr|A0A804HL78|A0A804HL78_HUMAN,tr|H3BQK9|H3BQK9_HUMAN,tr|A0A7P0MQR8|A0A7P0MQR8_HUMAN,tr|H0Y390|H0Y390_HUMAN,tr|H3BPE1|H3BPE1_HUMAN,tr|A0A590UJG2|A0A590UJG2_HUMAN" 7 1243.6772 21.49 14327 14200 2 1243.675838 622.8459 "Microtubule-actin cross-linking factor 1, isoforms 1\2\3\5 OS=Homo sapiens OX=9606 GN=MACF1 PE=1 SV=4" 4.37 2852 - 586668 - - - -1.108 - 2.382 0.596 - 397.8 1 2 0 -0.0014 11 0 0 0 3.93E+07 1.83E+06 - - - 5.7906 0.999 221125_WJC_METTL3_EV_vs_WT_F02.14203.14203.2 0.000433 24-Sep R.VGTVGYMAPEVVK.N "sp|P43250|GRK6_HUMAN,tr|D6RHX8|D6RHX8_HUMAN,tr|F8W9W2|F8W9W2_HUMAN" 3 1348.7061 999 14330 14203 2 1348.7074 675.3603 G protein-coupled receptor kinase 6 OS=Homo sapiens OX=9606 GN=GRK6 PE=1 SV=2 5.97 2852.3 - 417014 - - - 0.9832 - 1.868 0.271 - 171.5 1 2 0 0.0013 13 0 0 0 4.68E+06 0.00E+00 - - - 2.6459 0.9789 221125_WJC_METTL3_EV_vs_WT_F02.14204.14204.2 0.295 12-Jul R.SVTLLIK[136.11].G sp|P40227|TCPZ_HUMAN 1 780.52 0.46 14331 14204 2 780.519469 391.2673 T-complex protein 1 subunit zeta OS=Homo sapiens OX=9606 GN=CCT6A PE=1 SV=3 8.47 2852.4 - 275800 - - - -0.7328 - 1.331 0.031 - 165.5 1 2 0 -0.0006 7 0 0 0 1.56E+08 3.40E+08 - - - 0.1758 0.999 221125_WJC_METTL3_EV_vs_WT_F02.14208.14208.2 0.000259 18-Oct R.FPGQLNADLR[166.11].K "sp|P04350|TBB4A_HUMAN,sp|Q9BVA1|TBB2B_HUMAN,sp|A6NNZ2|TBB8B_HUMAN,sp|P07437|TBB5_HUMAN,sp|Q13509|TBB3_HUMAN,sp|Q13885|TBB2A_HUMAN,sp|P68371|TBB4B_HUMAN,sp|Q9BUF5|TBB6_HUMAN,sp|Q3ZCM7|TBB8_HUMAN,sp|Q9H4B7|TBB1_HUMAN,tr|M0R2D3|M0R2D3_HUMAN,tr|A0A0B4J269|A0A0B4J269_HUMAN,tr|Q5ST81|Q5ST81_HUMAN,tr|Q5JP53|Q5JP53_HUMAN,tr|K7ESM5|K7ESM5_HUMAN,tr|A0A075B736|A0A075B736_HUMAN,tr|G3V2A3|G3V2A3_HUMAN,tr|Q5SQY0|Q5SQY0_HUMAN" 18 1139.5963 0.7 14333 14208 2 1139.592974 570.8054 Tubulin beta-4A chain OS=Homo sapiens OX=9606 GN=TUBB4A PE=1 SV=2 5.84 2852.9 - 3.46E+06 - - - -2.8984 - 1.741 0.444 - 364.3 1 2 0 -0.0033 10 0 0 0 1.08E+08 1.55E+08 - - - 3.867 0.9999 221125_WJC_METTL3_EV_vs_WT_F02.14209.14209.2 9.62E-05 18-Nov R.LGDLYEEEMR[166.11].E "sp|P08670|VIME_HUMAN,tr|B0YJC4|B0YJC4_HUMAN" 2 1263.5681 1.88 14334 14209 2 1263.567526 632.7913 Vimentin OS=Homo sapiens OX=9606 GN=VIM PE=1 SV=4 4 2852.9 - 2.95E+07 - - - -0.4329 - 2.107 0.561 - 475.1 1 2 0 -0.0005 10 0 0 0 4.58E+09 2.43E+09 - - - 5.2646 0.9995 221125_WJC_METTL3_EV_vs_WT_F02.14211.14211.2 0.0241 16-Aug R.SGYITIGYR[166.11].G sp|Q96CX2|KCD12_HUMAN 1 1038.5374 1.69 14336 14211 2 1038.537798 520.276 BTB\POZ domain-containing protein KCTD12 OS=Homo sapiens OX=9606 GN=KCTD12 PE=1 SV=1 8.31 2853.1 - 911726 - - - 0.4169 - 1.539 0.387 - 183.3 1 2 0 0.0004 9 0 0 0 2.65E+07 1.56E+07 - - - 3.1465 0.995 221125_WJC_METTL3_EV_vs_WT_F02.14216.14216.2 0.116 14-Sep R.NAITVPFK.A sp|Q96QR8|PURB_HUMAN 1 888.5069 1.9 14340 14216 2 888.50556 445.2607 Transcriptional activator protein Pur-beta OS=Homo sapiens OX=9606 GN=PURB PE=1 SV=3 8.75 2853.7 - 1.02E+06 - - - -1.5115 - 1.457 0.169 - 315.5 1 2 0 -0.0013 8 0 0 0 2.57E+07 1.35E+07 - - - 1.424 0.9998 221125_WJC_METTL3_EV_vs_WT_F02.14218.14218.2 0.0016 18-Oct R.VTGGIFSVTK[136.11].G sp|Q8WUH6|TM263_HUMAN 1 1015.5793 1.12 14341 14218 2 1015.578439 508.7969 Transmembrane protein 263 OS=Homo sapiens OX=9606 GN=TMEM263 PE=1 SV=1 8.72 2853.9 - 3.88E+06 - - - -0.8941 - 1.987 0.42 - 239.5 1 2 0 -0.0009 10 0 0 0 3.10E+08 2.77E+08 - - - 4.0594 0.999 221125_WJC_METTL3_EV_vs_WT_F02.14219.14219.2 0.0121 14-Oct K.QVIIQGFR.S sp|Q9UQE7|SMC3_HUMAN 1 959.5553 0.78 14342 14219 2 959.554679 480.7849 Structural maintenance of chromosomes protein 3 OS=Homo sapiens OX=9606 GN=SMC3 PE=1 SV=2 9.75 2854 - 2.68E+06 - - - -0.5951 - 1.85 0.206 - 360 1 2 0 -0.0006 8 0 0 0 8.84E+07 1.14E+08 - - - 2.4177 0.9965 221125_WJC_METTL3_EV_vs_WT_F02.14221.14221.2 0.214 14-Aug K.ALDFIASK.G "sp|O43707|ACTN4_HUMAN,sp|Q08043|ACTN3_HUMAN,sp|P12814|ACTN1_HUMAN,tr|A0A804HJN7|A0A804HJN7_HUMAN,tr|A0A804HK61|A0A804HK61_HUMAN,tr|G3V2E8|G3V2E8_HUMAN,tr|G3V2W4|G3V2W4_HUMAN,tr|A0A804HIN7|A0A804HIN7_HUMAN,tr|G3V5M4|G3V5M4_HUMAN,tr|H9KV75|H9KV75_HUMAN,tr|A0A087WSZ2|A0A087WSZ2_HUMAN,tr|A0A804HLF4|A0A804HLF4_HUMAN,tr|A0A804HIY0|A0A804HIY0_HUMAN,tr|A0A7I2V4Y4|A0A7I2V4Y4_HUMAN,tr|A0A804HII9|A0A804HII9_HUMAN,tr|A0A804HL31|A0A804HL31_HUMAN,tr|A0A804HJQ9|A0A804HJQ9_HUMAN,tr|F5GXS2|F5GXS2_HUMAN,tr|G3V2X9|G3V2X9_HUMAN,tr|A0A804HKE2|A0A804HKE2_HUMAN,tr|G3V2N5|G3V2N5_HUMAN,tr|A0A804HLD0|A0A804HLD0_HUMAN,tr|H7C144|H7C144_HUMAN" 23 863.4753 1.13 14344 14221 2 863.474556 432.7449 Alpha-actinin-4 OS=Homo sapiens OX=9606 GN=ACTN4 PE=1 SV=2 5.88 2854.1 - 3.01E+06 - - - -0.8257 - 1.604 0.132 - 198 1 2 0 -0.0007 8 0 0 0 8.97E+07 7.93E+07 - - - 1.4408 0.9796 221125_WJC_METTL3_EV_vs_WT_F02.14222.14222.2 3.36 14-Jun R.NVVYPLYR[166.11].L "sp|Q16540|RM23_HUMAN,tr|A8MYK1|A8MYK1_HUMAN,tr|A8MVT4|A8MVT4_HUMAN,tr|A6NJD9|A6NJD9_HUMAN" 4 1032.5632 1.37 14345 14222 2 1032.563534 517.2889 "39S ribosomal protein L23, mitochondrial OS=Homo sapiens OX=9606 GN=MRPL23 PE=1 SV=1" 8.59 2854.1 - 1.67E+06 - - - 0.337 - 1.203 0.078 - 162.7 1 2 0 0.0003 8 0 0 0 4.01E+07 2.92E+07 - - - 0.1744 0.9995 221125_WJC_METTL3_EV_vs_WT_F02.14223.14223.2 1.33E-05 13/20 R.VSGGLEVLAEK.C "sp|O43423|AN32C_HUMAN,sp|P39687|AN32A_HUMAN,tr|H0YN26|H0YN26_HUMAN" 3 1100.6077 2.28 14346 14223 2 1100.604352 551.3111 Acidic leucine-rich nuclear phosphoprotein 32 family member C OS=Homo sapiens OX=9606 GN=ANP32C PE=2 SV=1 4.53 2854.2 - 1.34E+06 - - - -3.0783 - 2.49 0.483 - 407 1 2 0 -0.0034 11 0 0 0 3.44E+07 1.51E+07 - - - 5.0753 0.9405 221125_WJC_METTL3_EV_vs_WT_F02.14226.14226.2 0.373 12-Jul R.SVTLLIK.G sp|P40227|TCPZ_HUMAN 1 772.5058 0.46 14349 14226 2 772.503997 387.2602 T-complex protein 1 subunit zeta OS=Homo sapiens OX=9606 GN=CCT6A PE=1 SV=3 8.47 2854.5 - 490968 - - - -2.387 - 1.314 0.027 - 154.3 1 2 0 -0.0018 7 0 0 0 1.56E+08 3.39E+08 - - - 0.1051 0.9998 221125_WJC_METTL3_EV_vs_WT_F02.14229.14229.2 0.00747 18-Oct R.VWDVESGSLK.S sp|Q9GZL7|WDR12_HUMAN 1 1118.5608 1.42 14350 14229 2 1118.560008 560.2877 Ribosome biogenesis protein WDR12 OS=Homo sapiens OX=9606 GN=WDR12 PE=1 SV=2 4.37 2854.9 - 1.87E+06 - - - -0.6982 - 2.002 0.474 - 319.5 1 2 0 -0.0008 10 0 0 0 5.43E+07 3.83E+07 - - - 4.4793 0.9992 221125_WJC_METTL3_EV_vs_WT_F02.14231.14231.3 3.24E-06 15/40 K.FAAQELIEVK[136.11]R[166.11].G "sp|Q86U44|MTA70_HUMAN,tr|F5H6D8|F5H6D8_HUMAN,tr|H0YFV6|H0YFV6_HUMAN,tr|B4DTN4|B4DTN4_HUMAN" 4 1320.7521 0.22 14352 14231 3 1320.74998 441.258 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 6.14 2855.1 - 1.90E+06 - - - -1.5718 - 2.515 0.231 - 219.4 1 2 0 -0.0021 11 0 0 0 1.57E+07 7.27E+07 - - - 3.7349 0.9989 221125_WJC_METTL3_EV_vs_WT_F02.14232.14232.2 0.0221 16-Aug R.DIATIVADK.C "sp|Q9Y3A5|SBDS_HUMAN,tr|A0A087X020|A0A087X020_HUMAN" 2 944.5179 2.09 14353 14232 2 944.516975 473.2662 Ribosome maturation protein SBDS OS=Homo sapiens OX=9606 GN=SBDS PE=1 SV=4 4.21 2855.2 - 1.46E+06 - - - -0.9391 - 1.489 0.298 - 172 1 2 0 -0.0009 9 0 0 0 3.38E+07 1.61E+07 - - - 2.3935 0.9992 221125_WJC_METTL3_EV_vs_WT_F02.14233.14233.2 0.136 14-Sep K.LAVEILNK.E "sp|P19525|E2AK2_HUMAN,tr|A0A7P0TAL9|A0A7P0TAL9_HUMAN,tr|A0A7P0Z4M0|A0A7P0Z4M0_HUMAN,tr|A0A7P0TBA9|A0A7P0TBA9_HUMAN" 4 898.5488 1.12 14354 14233 2 898.548462 450.2817 "Interferon-induced, double-stranded RNA-activated protein kinase OS=Homo sapiens OX=9606 GN=EIF2AK2 PE=1 SV=2" 6 2855.3 - 1.21E+06 - - - -0.3405 - 1.881 0.226 - 223.1 1 2 0 -0.0003 8 0 0 0 3.35E+07 2.99E+07 - - - 2.6156 0.9903 221125_WJC_METTL3_EV_vs_WT_F02.14237.14237.2 0.385 12-Jun K.DSLINLK[136.11].L "sp|Q8N5K1|CISD2_HUMAN,tr|D6RCF4|D6RCF4_HUMAN" 2 809.4738 1.27 14356 14237 2 809.472945 405.7442 CDGSH iron-sulfur domain-containing protein 2 OS=Homo sapiens OX=9606 GN=CISD2 PE=1 SV=1 5.84 2855.7 - 2.15E+06 - - - -1.0797 - 1.324 0.116 - 149.5 1 2 0 -0.0009 7 0 0 0 5.50E+07 4.34E+07 - - - 0.7868 0.9993 221125_WJC_METTL3_EV_vs_WT_F02.14241.14241.2 0.039 18-Jul K.ILYLTPEQEK.D "sp|P62495|ERF1_HUMAN,tr|B7Z7P8|B7Z7P8_HUMAN" 2 1232.6653 0.8 14358 14241 2 1232.665377 617.3399 Eukaryotic peptide chain release factor subunit 1 OS=Homo sapiens OX=9606 GN=ETF1 PE=1 SV=3 4.53 2856.2 - 209149 - - - 0.099 - 1.594 0.314 - 115.6 1 2 0 0.0001 10 0 0 0 5.44E+06 6.82E+06 - - - 2.6616 0.9989 221125_WJC_METTL3_EV_vs_WT_F02.14242.14242.2 0.0638 14-Jul R.ELLAALQK[136.11].V "sp|Q8IWX8|CHERP_HUMAN,tr|J3QK89|J3QK89_HUMAN" 2 892.5473 0.97 14359 14242 2 892.547352 447.2809 Calcium homeostasis endoplasmic reticulum protein OS=Homo sapiens OX=9606 GN=CHERP PE=1 SV=3 6.1 2856.3 - 986057 - - - 0.0381 - 1.272 0.337 - 113.5 1 2 0 0 8 0 0 0 5.77E+07 5.93E+07 - - - 2.2557 0.9984 221125_WJC_METTL3_EV_vs_WT_F02.14244.14244.2 0.00174 20-Oct R.IPWTAASSQLK[136.11].E "sp|Q9GZT3|SLIRP_HUMAN,tr|H0YJW7|H0YJW7_HUMAN,tr|A0A087WUN7|A0A087WUN7_HUMAN,tr|G3V2S9|G3V2S9_HUMAN,tr|H0YJU7|H0YJU7_HUMAN,tr|H0YJ07|H0YJ07_HUMAN,tr|H0YJ40|H0YJ40_HUMAN,tr|G3V4X6|G3V4X6_HUMAN" 8 1208.6645 1.28 14361 14244 2 1208.667395 605.3395 "SRA stem-loop-interacting RNA-binding protein, mitochondrial OS=Homo sapiens OX=9606 GN=SLIRP PE=1 SV=1" 8.75 2856.6 - 599508 - - - 2.4175 - 1.528 0.38 - 265.3 1 2 0 0.0029 11 0 0 0 1.29E+09 1.01E+09 - - - 2.9937 0.9989 221125_WJC_METTL3_EV_vs_WT_F02.14251.14251.2 0.00833 14-Aug R.ELLAALQK.V "sp|Q8IWX8|CHERP_HUMAN,tr|J3QK89|J3QK89_HUMAN" 2 884.5331 0.97 14366 14251 2 884.532205 443.2738 Calcium homeostasis endoplasmic reticulum protein OS=Homo sapiens OX=9606 GN=CHERP PE=1 SV=3 6.1 2857.4 - 1.39E+06 - - - -1.0322 - 1.521 0.291 - 165.5 1 2 0 -0.0009 8 0 0 0 5.77E+07 5.93E+07 - - - 2.4548 0.9885 221125_WJC_METTL3_EV_vs_WT_F02.14253.14253.2 1.72 20-May R.EAIIPGSVYDR[166.11].S sp|Q92900|RENT1_HUMAN 1 1228.6327 1.03 14368 14253 2 1228.632629 615.3236 Regulator of nonsense transcripts 1 OS=Homo sapiens OX=9606 GN=UPF1 PE=1 SV=2 4.37 2857.6 - 364506 - - - -0.0757 - 1.313 0.119 - 88.2 2 2 0 -0.0001 11 0 0 0 1.46E+08 1.42E+08 - - - 0.5221 0.987 221125_WJC_METTL3_EV_vs_WT_F02.14254.14254.2 1.4 24-May R.LLEFYDATAHFAK[136.11].G sp|P83436|COG7_HUMAN 1 1532.7755 0.001 14369 14254 2 1532.77497 767.395 Conserved oligomeric Golgi complex subunit 7 OS=Homo sapiens OX=9606 GN=COG7 PE=1 SV=1 5.32 2857.7 - 333992 - - - -0.3327 - 1.078 0.164 - 43.1 1 2 0 -0.0005 13 0 0 0 0.00E+00 4.54E+06 - - - 0.4449 0.9995 221125_WJC_METTL3_EV_vs_WT_F02.14258.14258.2 0.00562 16-Sep K.LTENLVALK.E "sp|Q00537|CDK17_HUMAN,sp|Q07002|CDK18_HUMAN,tr|A0A0A0MSJ6|A0A0A0MSJ6_HUMAN,tr|F5H6Z0|F5H6Z0_HUMAN" 4 999.5964 1.05 14371 14258 2 999.595607 500.8055 Cyclin-dependent kinase 17 OS=Homo sapiens OX=9606 GN=CDK17 PE=1 SV=2 6 2858.1 - 2.37E+06 - - - -0.8403 - 2.04 0.277 - 196.5 1 2 0 -0.0008 9 0 0 0 4.62E+07 4.39E+07 - - - 3.1493 0.9993 221125_WJC_METTL3_EV_vs_WT_F02.14259.14259.2 0.0365 16-Sep R.LNELMSQIR.M sp|Q7Z3B4|NUP54_HUMAN 1 1102.5805 2.33 14372 14259 2 1102.578203 552.2975 Nucleoporin p54 OS=Homo sapiens OX=9606 GN=NUP54 PE=1 SV=2 6 2858.2 - 1.39E+06 - - - -2.0642 - 2.029 0.343 - 305.7 1 2 0 -0.0023 9 0 0 0 2.89E+08 1.24E+08 - - - 3.6206 0.9889 221125_WJC_METTL3_EV_vs_WT_F02.14260.14260.2 0.0121 20-Nov K.AIFQQPPVGVR[166.11].K "sp|Q7L2E3|DHX30_HUMAN,tr|H7BXY3|H7BXY3_HUMAN" 2 1220.6905 0.01 14373 14260 2 1220.69614 611.3525 ATP-dependent RNA helicase DHX30 OS=Homo sapiens OX=9606 GN=DHX30 PE=1 SV=1 9.79 2858.3 - 593925 - - - 4.6105 - 1.873 0.257 - 386.1 1 2 0 0.0056 11 0 0 0 8.90E+06 1.18E+09 - - - 2.6351 0.9933 221125_WJC_METTL3_EV_vs_WT_F02.14263.14263.2 0.274 18-Jul R.VIITNFPAAK[136.11].S "sp|P47897|SYQ_HUMAN,tr|B4DDN1|B4DDN1_HUMAN,tr|H7C0R3|H7C0R3_HUMAN,tr|A0A1B0GVU9|A0A1B0GVU9_HUMAN" 4 1080.6423 1.02 14374 14263 2 1080.63843 541.3284 Glutamine--tRNA ligase OS=Homo sapiens OX=9606 GN=QARS1 PE=1 SV=1 8.72 2858.7 - 1.83E+06 - - - -3.5636 - 1.571 0.281 - 122.6 1 2 0 -0.0039 10 0 0 0 1.36E+08 1.33E+08 - - - 2.3761 0.996 221125_WJC_METTL3_EV_vs_WT_F02.14264.14264.2 0.0738 14-Aug K.STLLFGQR.A sp|P33176|KINH_HUMAN 1 920.508 0.49 14375 14264 2 920.507127 461.2613 Kinesin-1 heavy chain OS=Homo sapiens OX=9606 GN=KIF5B PE=1 SV=1 9.47 2858.8 - 1.44E+06 - - - -0.9115 - 1.625 0.116 - 207.8 1 2 0 -0.0008 8 0 0 0 4.18E+07 8.50E+07 - - - 1.3618 0.9973 221125_WJC_METTL3_EV_vs_WT_F02.14265.14265.2 7.56E-06 18-Sep R.EAMNDPLLER.Y sp|O43143|DHX15_HUMAN 1 1186.5652 1.05 14376 14265 2 1186.559235 594.2899 Pre-mRNA-splicing factor ATP-dependent RNA helicase DHX15 OS=Homo sapiens OX=9606 GN=DHX15 PE=1 SV=2 4.14 2858.9 - 1.64E+06 - - - -5.0465 - 1.724 0.553 - 282.1 1 2 0 -0.006 10 0 0 0 1.09E+08 1.04E+08 - - - 4.6439 0.9993 221125_WJC_METTL3_EV_vs_WT_F02.14267.14267.2 0.00651 14-Aug K.ELEDAYWK[136.11].D "sp|Q96CT7|CC124_HUMAN,tr|M0R2F5|M0R2F5_HUMAN" 2 1060.4957 0.86 14378 14267 2 1060.494281 531.2551 Coiled-coil domain-containing protein 124 OS=Homo sapiens OX=9606 GN=CCDC124 PE=1 SV=1 4.14 2859 - 1.15E+06 - - - -1.3154 - 1.388 0.408 - 198.2 1 2 0 -0.0014 8 0 0 0 2.89E+07 3.37E+07 - - - 3.0429 0.9995 221125_WJC_METTL3_EV_vs_WT_F02.14268.14268.2 0.00505 22-Dec R.GVLVVGIGSGTK[136.11].M sp|Q8WWH5|TRUB1_HUMAN 1 1093.6587 1.07 14379 14268 2 1093.656408 547.8366 Probable tRNA pseudouridine synthase 1 OS=Homo sapiens OX=9606 GN=TRUB1 PE=1 SV=1 8.75 2859.2 - 241379 - - - -2.0582 - 2.341 0.36 - 375.4 1 2 0 -0.0023 12 0 0 0 1.89E+07 1.77E+07 - - - 3.9373 0.9997 221125_WJC_METTL3_EV_vs_WT_F02.14271.14271.2 0.0095 16-Sep R.LNELMSQIR[166.11].M sp|Q7Z3B4|NUP54_HUMAN 1 1112.5887 2.35 14380 14271 2 1112.588833 557.3017 Nucleoporin p54 OS=Homo sapiens OX=9606 GN=NUP54 PE=1 SV=2 6 2859.6 - 2.29E+06 - - - 0.0755 - 2.146 0.344 - 338 1 2 0 0.0001 9 0 0 0 2.91E+08 1.24E+08 - - - 3.7909 0.9553 221125_WJC_METTL3_EV_vs_WT_F02.14272.14272.2 0.0695 16-Jun R.LEAPELPVK.V "sp|Q8IZQ5|SELH_HUMAN,tr|H0YE28|H0YE28_HUMAN,tr|A0A087WYP2|A0A087WYP2_HUMAN" 3 994.5699 1.07 14381 14272 2 994.575045 498.2922 Selenoprotein H OS=Homo sapiens OX=9606 GN=SELENOH PE=1 SV=2 4.53 2859.6 - 1.60E+06 - - - 5.1751 - 1.428 0.229 - 102.6 1 2 0 0.0051 9 0 0 0 7.27E+07 6.81E+07 - - - 1.7615 0.9875 221125_WJC_METTL3_EV_vs_WT_F02.14273.14273.2 0.502 12-Aug K.SVIISIK[136.11].G "sp|Q0IIM8|TBC8B_HUMAN,sp|P09496|CLCA_HUMAN,tr|J3KN75|J3KN75_HUMAN,tr|C9J8P9|C9J8P9_HUMAN,tr|D6RFZ2|D6RFZ2_HUMAN" 5 766.5044 0.41 14382 14273 2 766.503392 384.2595 TBC1 domain family member 8B OS=Homo sapiens OX=9606 GN=TBC1D8B PE=1 SV=2 8.47 2859.8 - 993013 - - - -1.3033 - 1.443 0.066 - 233.9 1 2 0 -0.001 7 0 0 0 4.20E+07 1.03E+08 - - - 0.6901 0.9791 221125_WJC_METTL3_EV_vs_WT_F02.14277.14277.2 0.084 14-Jul K.ELEDFEMK.K "sp|Q9UG63|ABCF2_HUMAN,tr|C9JZV3|C9JZV3_HUMAN,tr|C9JHK9|C9JHK9_HUMAN" 3 1039.4532 0.27 14386 14277 2 1039.455549 520.7339 ATP-binding cassette sub-family F member 2 OS=Homo sapiens OX=9606 GN=ABCF2 PE=1 SV=2 4 2860.2 - 512365 - - - 2.2473 - 1.185 0.168 - 156.8 1 2 0 0.0023 8 0 0 0 1.06E+07 3.92E+07 - - - 0.7931 0.9992 221125_WJC_METTL3_EV_vs_WT_F02.14281.14281.2 0.00862 12-Jul R.IWSLEGK[136.11].S sp|Q9GZL7|WDR12_HUMAN 1 839.4633 9.02 14388 14281 2 839.462776 420.7389 Ribosome biogenesis protein WDR12 OS=Homo sapiens OX=9606 GN=WDR12 PE=1 SV=2 6 2860.6 - 1.46E+06 - - - -0.5694 - 1.468 0.325 - 153.1 1 2 0 -0.0005 7 0 0 0 1.07E+09 1.19E+08 - - - 2.6577 0.9991 221125_WJC_METTL3_EV_vs_WT_F02.14284.14284.2 0.00154 14-May K.EC[160.03]ADLWPR.L "sp|P62829|RL23_HUMAN,tr|J3KTJ3|J3KTJ3_HUMAN" 2 1045.4651 0.91 14391 14284 2 1045.464194 523.7398 60S ribosomal protein L23 OS=Homo sapiens OX=9606 GN=RPL23 PE=1 SV=1 4.37 2860.8 - 2.11E+06 - - - -0.8809 - 1.321 0.369 - 126.6 1 2 0 -0.0009 8 0 0 0 2.14E+08 2.36E+08 - - - 2.6058 0.999 221125_WJC_METTL3_EV_vs_WT_F02.14286.14286.2 0.217 18-Aug R.LQEVLNDYYK.E "sp|Q96GA3|LTV1_HUMAN,tr|A0A075B6Q4|A0A075B6Q4_HUMAN" 2 1283.6398 0.96 14393 14286 2 1283.642053 642.8272 Protein LTV1 homolog OS=Homo sapiens OX=9606 GN=LTV1 PE=1 SV=1 4.37 2860.9 - 805856 - - - 1.7801 - 1.816 0.318 - 256.3 1 2 0 0.0023 10 0 0 0 2.64E+07 2.74E+07 - - - 3.0544 0.9996 221125_WJC_METTL3_EV_vs_WT_F02.14290.14290.2 0.00241 20-Nov R.EAIIPGSVYDR.S sp|Q92900|RENT1_HUMAN 1 1218.6245 1.03 14395 14290 2 1218.624499 610.3195 Regulator of nonsense transcripts 1 OS=Homo sapiens OX=9606 GN=UPF1 PE=1 SV=2 4.37 2861.4 - 1.48E+06 - - - 0.0386 - 1.983 0.303 - 400.9 1 2 0 0 11 0 0 0 1.46E+08 1.42E+08 - - - 3.131 0.8805 221125_WJC_METTL3_EV_vs_WT_F02.14292.14292.2 0.0171 14-Jul S.LAELTGIK.W "sp|Q71F56|MD13L_HUMAN,tr|A0A3B3IS36|A0A3B3IS36_HUMAN,tr|A0A3B3IRX3|A0A3B3IRX3_HUMAN" 3 843.5066 0.93 14397 14292 2 843.508117 422.7606 Mediator of RNA polymerase II transcription subunit 13-like OS=Homo sapiens OX=9606 GN=MED13L PE=1 SV=1 6 2861.5 - 1.82E+06 - - - 1.8352 - 1.486 0.28 - 143.6 1 1 0 0.0015 8 0 0 0 1.14E+09 1.22E+09 - - - 2.3032 0.9965 221125_WJC_METTL3_EV_vs_WT_F02.14294.14294.2 1.97 12-Jul K.SVIISIK.G "sp|Q0IIM8|TBC8B_HUMAN,sp|P09496|CLCA_HUMAN,tr|J3KN75|J3KN75_HUMAN,tr|C9J8P9|C9J8P9_HUMAN,tr|D6RFZ2|D6RFZ2_HUMAN" 5 758.4902 0.41 14399 14294 2 758.489504 380.2524 TBC1 domain family member 8B OS=Homo sapiens OX=9606 GN=TBC1D8B PE=1 SV=2 8.47 2861.8 - 437304 - - - -0.9057 - 1.445 0.171 - 182.9 1 2 0 -0.0007 7 0 0 0 4.20E+07 1.03E+08 - - - 1.4702 0.9999 221125_WJC_METTL3_EV_vs_WT_F02.14298.14298.2 0.00114 18-Dec R.LSSLIIGPSK[136.11].E "sp|Q92615|LAR4B_HUMAN,tr|H0Y641|H0Y641_HUMAN,tr|H0Y4V9|H0Y4V9_HUMAN" 3 1021.6263 1.2 14401 14298 2 1021.625719 511.8204 La-related protein 4B OS=Homo sapiens OX=9606 GN=LARP4B PE=1 SV=3 8.75 2862.3 - 7.80E+06 - - - -0.5658 - 2.452 0.462 - 435.1 1 2 0 -0.0006 10 0 0 0 1.77E+09 1.48E+09 - - - 4.9567 0.9997 221125_WJC_METTL3_EV_vs_WT_F02.14300.14300.2 8.76E-05 22-Oct K.FFADDTQAALTK.H sp|O94874|UFL1_HUMAN 1 1326.6456 8.02 14403 14300 2 1326.645828 664.3301 E3 UFM1-protein ligase 1 OS=Homo sapiens OX=9606 GN=UFL1 PE=1 SV=2 4.21 2862.6 - 437554 - - - 0.1854 - 1.572 0.477 - 178.7 1 2 0 0.0002 12 0 0 0 4.45E+07 5.55E+06 - - - 3.7543 0.9998 221125_WJC_METTL3_EV_vs_WT_F02.14304.14304.2 0.00121 18-Dec R.LSSLIIGPSK.E "sp|Q92615|LAR4B_HUMAN,tr|H0Y641|H0Y641_HUMAN,tr|H0Y4V9|H0Y4V9_HUMAN" 3 1013.6121 1.2 14405 14304 2 1013.612873 507.8133 La-related protein 4B OS=Homo sapiens OX=9606 GN=LARP4B PE=1 SV=3 8.75 2863.1 - 9.56E+06 - - - 0.7656 - 2.293 0.393 - 449.8 1 2 0 0.0008 10 0 0 0 1.77E+09 1.48E+09 - - - 4.2598 0.998 221125_WJC_METTL3_EV_vs_WT_F02.14308.14308.2 0.00757 20-Sep K.IFPGLAADQSR.A "sp|Q13425|SNTB2_HUMAN,tr|A0A140TA73|A0A140TA73_HUMAN,tr|J3KT21|J3KT21_HUMAN,tr|H0YCS0|H0YCS0_HUMAN,tr|A0A0G2JM75|A0A0G2JM75_HUMAN" 5 1173.6142 0.65 14408 14308 2 1173.615381 587.8144 Beta-2-syntrophin OS=Homo sapiens OX=9606 GN=SNTB2 PE=1 SV=1 5.84 2863.5 - 584984 - - - 0.9875 - 1.459 0.264 - 215.3 1 2 0 0.0012 11 0 0 0 3.58E+07 5.47E+07 - - - 2.0124 0.9999 221125_WJC_METTL3_EV_vs_WT_F02.14312.14312.2 4.18E-06 20-Nov K.YGQISEVVVVK.D "sp|Q14011|CIRBP_HUMAN,tr|K7ER40|K7ER40_HUMAN,tr|K7ENX8|K7ENX8_HUMAN,tr|K7EJV1|K7EJV1_HUMAN,tr|K7EJV5|K7EJV5_HUMAN,tr|K7ELT6|K7ELT6_HUMAN,tr|K7EMY9|K7EMY9_HUMAN,tr|K7ELV6|K7ELV6_HUMAN,tr|K7EQR7|K7EQR7_HUMAN,tr|K7EPM4|K7EPM4_HUMAN,tr|D6W5Y5|D6W5Y5_HUMAN" 11 1219.6812 0.95 14411 14312 2 1219.681113 610.8479 Cold-inducible RNA-binding protein OS=Homo sapiens OX=9606 GN=CIRBP PE=1 SV=1 6 2863.9 - 5.15E+06 - - - -0.1033 - 2.207 0.545 - 358.1 1 2 0 -0.0001 11 0 0 0 1.95E+09 2.06E+09 - - - 5.2079 0.9996 221125_WJC_METTL3_EV_vs_WT_F02.14316.14316.2 0.000987 16-Oct R.WESGSLLER[166.11].E "sp|O14776|TCRG1_HUMAN,tr|A0A7P0T8N8|A0A7P0T8N8_HUMAN,tr|G3V220|G3V220_HUMAN" 3 1085.5381 0.6 14413 14316 2 1085.537979 543.7763 Transcription elongation regulator 1 OS=Homo sapiens OX=9606 GN=TCERG1 PE=1 SV=2 4.53 2864.4 - 1.29E+06 - - - -0.1059 - 1.804 0.328 - 313.4 1 2 0 -0.0001 9 0 0 0 2.82E+07 4.71E+07 - - - 3.1705 0.9997 221125_WJC_METTL3_EV_vs_WT_F02.14319.14319.2 9.63E-05 18-Sep R.VIITNFPAAK.S "sp|P47897|SYQ_HUMAN,tr|B4DDN1|B4DDN1_HUMAN,tr|H7C0R3|H7C0R3_HUMAN,tr|A0A1B0GVU9|A0A1B0GVU9_HUMAN" 4 1072.6281 1.01 14414 14319 2 1072.627424 537.3213 Glutamine--tRNA ligase OS=Homo sapiens OX=9606 GN=QARS1 PE=1 SV=1 8.72 2864.8 - 1.83E+06 - - - -0.6125 - 1.824 0.418 - 235.1 1 2 0 -0.0007 10 0 0 0 1.35E+08 1.34E+08 - - - 3.8058 0.9962 221125_WJC_METTL3_EV_vs_WT_F02.14320.14320.2 0.00229 20-Oct K.TTVLAMDQVPR[166.11].V "sp|Q13423|NNTM_HUMAN,tr|D6RHU2|D6RHU2_HUMAN,tr|A0A590UJA4|A0A590UJA4_HUMAN,tr|E9PCX7|E9PCX7_HUMAN,tr|D6RCR6|D6RCR6_HUMAN,tr|D6RAI5|D6RAI5_HUMAN,tr|A0A590UK15|A0A590UK15_HUMAN,tr|A0A590UJM2|A0A590UJM2_HUMAN,tr|A0A590UK29|A0A590UK29_HUMAN,tr|A0A590UKC7|A0A590UKC7_HUMAN,tr|A0A590UJI3|A0A590UJI3_HUMAN" 11 1239.6521 4.25 14415 14320 2 1239.646334 620.8333 "NAD(P) transhydrogenase, mitochondrial OS=Homo sapiens OX=9606 GN=NNT PE=1 SV=3" 5.5 2864.9 - 178648 - - - -4.6336 - 1.747 0.433 - 244.4 1 2 0 -0.0057 11 0 0 0 7.67E+07 1.80E+07 - - - 3.7466 0.9984 221125_WJC_METTL3_EV_vs_WT_F02.14330.14330.3 0.0141 Nov-40 K.YGQISEVVVVK[136.11].D "sp|Q14011|CIRBP_HUMAN,tr|K7ER40|K7ER40_HUMAN,tr|K7ENX8|K7ENX8_HUMAN,tr|K7EJV1|K7EJV1_HUMAN,tr|K7EJV5|K7EJV5_HUMAN,tr|K7ELT6|K7ELT6_HUMAN,tr|K7EMY9|K7EMY9_HUMAN,tr|K7ELV6|K7ELV6_HUMAN,tr|K7EQR7|K7EQR7_HUMAN,tr|K7EPM4|K7EPM4_HUMAN,tr|D6W5Y5|D6W5Y5_HUMAN" 11 1227.6954 0.56 14423 14330 3 1227.694955 410.2391 Cold-inducible RNA-binding protein OS=Homo sapiens OX=9606 GN=CIRBP PE=1 SV=1 6 2866.1 - 522305 - - - -0.3942 - 1.852 0.24 - 142.1 1 2 0 -0.0005 11 0 0 0 4.27E+07 7.68E+07 - - - 2.9663 0.9965 221125_WJC_METTL3_EV_vs_WT_F02.14331.14331.2 0.0384 20-Aug R.FISALNNVAER[166.11].T "sp|Q9UJA3|MCM8_HUMAN,tr|A0A494C100|A0A494C100_HUMAN" 2 1242.6596 0.97 14424 14331 2 1242.656492 622.3371 DNA helicase MCM8 OS=Homo sapiens OX=9606 GN=MCM8 PE=1 SV=2 6 2866.2 - 292994 - - - -2.5059 - 1.293 0.342 - 144.7 1 2 0 -0.0031 11 0 0 0 2.42E+07 2.49E+07 - - - 2.2612 0.9876 221125_WJC_METTL3_EV_vs_WT_F02.14334.14334.2 0.838 14-Jun R.LFVGSIPK[136.11].S "sp|O60506|HNRPQ_HUMAN,sp|O43390|HNRPR_HUMAN,tr|A0A7I2YQV8|A0A7I2YQV8_HUMAN,tr|B4DT28|B4DT28_HUMAN,tr|A0A7I2YQN2|A0A7I2YQN2_HUMAN,tr|A0A7I2V5Q6|A0A7I2V5Q6_HUMAN,tr|A0A7I2V4Z0|A0A7I2V4Z0_HUMAN,tr|A0A6Q8PHG0|A0A6Q8PHG0_HUMAN,tr|B7Z645|B7Z645_HUMAN,tr|A0A6Q8PH31|A0A6Q8PH31_HUMAN,tr|A0A6Q8PEX7|A0A6Q8PEX7_HUMAN,tr|A0A7I2V2F2|A0A7I2V2F2_HUMAN,tr|A0A7I2V346|A0A7I2V346_HUMAN,tr|A0A7I2V309|A0A7I2V309_HUMAN" 14 867.5309 0.86 14425 14334 2 867.530962 434.7727 Heterogeneous nuclear ribonucleoprotein Q OS=Homo sapiens OX=9606 GN=SYNCRIP PE=1 SV=2 8.75 2866.6 - 928879 - - - 0.0254 - 1.264 0.098 - 103.2 1 2 0 0 8 0 0 0 8.37E+07 9.72E+07 - - - 0.4714 0.9975 221125_WJC_METTL3_EV_vs_WT_F02.14339.14339.2 0.141 12-Jul K.DVDALLK.K sp|O75528|TADA3_HUMAN 1 772.4331 1.26 14428 14339 2 772.432573 387.2238 Transcriptional adapter 3 OS=Homo sapiens OX=9606 GN=TADA3 PE=1 SV=1 4.21 2867.2 - 2.34E+06 - - - -0.6434 - 1.307 0.242 - 182.8 1 2 0 -0.0005 7 0 0 0 5.47E+07 4.33E+07 - - - 1.6766 0.9999 221125_WJC_METTL3_EV_vs_WT_F02.14340.14340.2 0.000159 26-Nov R.LVPGGGATEIELAK[136.11].Q sp|P50990|TCPQ_HUMAN 1 1361.7646 0.42 14429 14340 2 1361.763647 681.8896 T-complex protein 1 subunit theta OS=Homo sapiens OX=9606 GN=CCT8 PE=1 SV=4 4.53 2867.4 - 1.42E+06 - - - -0.6859 - 2.142 0.527 - 282.7 1 2 0 -0.0009 14 0 0 0 1.77E+09 4.24E+09 - - - 4.8447 0.985 221125_WJC_METTL3_EV_vs_WT_F02.14341.14341.2 0.859 12-Jul R.FGSSLFK[136.11].M sp|Q5W0B1|OBI1_HUMAN 1 792.4261 0.78 14430 14341 2 792.425323 397.2203 ORC ubiquitin ligase 1 OS=Homo sapiens OX=9606 GN=OBI1 PE=1 SV=1 8.75 2867.5 - 476598 - - - -1.031 - 1.228 0.106 - 111.7 1 2 0 -0.0008 7 0 0 0 1.78E+07 2.29E+07 - - - 0.4744 0.9998 221125_WJC_METTL3_EV_vs_WT_F02.14352.14352.2 9.42E-07 26-Dec R.LVPGGGATEIELAK.Q sp|P50990|TCPQ_HUMAN 1 1353.7504 0.42 14437 14352 2 1353.749621 677.8825 T-complex protein 1 subunit theta OS=Homo sapiens OX=9606 GN=CCT8 PE=1 SV=4 4.53 2868.8 - 565538 - - - -0.5614 - 1.916 0.519 - 345.2 1 2 0 -0.0008 14 0 0 0 1.77E+09 4.23E+09 - - - 4.5058 0.9935 221125_WJC_METTL3_EV_vs_WT_F02.14353.14353.2 0.176 12-Jun R.FGSSLFK.M sp|Q5W0B1|OBI1_HUMAN 1 784.4119 0.77 14438 14353 2 784.410709 393.2132 ORC ubiquitin ligase 1 OS=Homo sapiens OX=9606 GN=OBI1 PE=1 SV=1 8.75 2869 - 480319 - - - -1.5693 - 1.23 0.212 - 80.4 1 2 0 -0.0012 7 0 0 0 1.77E+07 2.29E+07 - - - 1.2624 0.9966 221125_WJC_METTL3_EV_vs_WT_F02.14359.14359.2 0.00266 16-Sep K.EGEFVAQFK[136.11].F sp|Q9UQ80|PA2G4_HUMAN 1 1061.5273 0.19 14442 14359 2 1061.525127 531.7709 Proliferation-associated protein 2G4 OS=Homo sapiens OX=9606 GN=PA2G4 PE=1 SV=3 4.53 2869.6 - 528432 - - - -2.0574 - 1.411 0.267 - 264.2 1 2 0 -0.0022 9 0 0 0 8.25E+06 4.35E+07 - - - 2.0085 0.9993 221125_WJC_METTL3_EV_vs_WT_F02.14364.14364.2 0.00139 14-Jul K.EYTLDVYR[166.11].L "sp|P54577|SYYC_HUMAN,tr|A0A6Q8PFX4|A0A6Q8PFX4_HUMAN,tr|A0A6Q8PF15|A0A6Q8PF15_HUMAN,tr|A0A0C4DGZ5|A0A0C4DGZ5_HUMAN,tr|A0A6Q8PFX2|A0A6Q8PFX2_HUMAN" 5 1067.5163 0.46 14445 14364 2 1067.51706 534.7654 "Tyrosine--tRNA ligase, cytoplasmic OS=Homo sapiens OX=9606 GN=YARS1 PE=1 SV=4" 4.37 2870.1 - 1.04E+06 - - - 0.7157 - 1.535 0.342 - 223.8 1 2 0 0.0008 8 0 0 0 5.82E+07 1.28E+08 - - - 2.8592 0.9742 221125_WJC_METTL3_EV_vs_WT_F02.14369.14369.2 2.71 14-Jun R.LSVPDIPK[136.11].E "sp|Q96N67|DOCK7_HUMAN,tr|A0A0C4DGY6|A0A0C4DGY6_HUMAN,tr|A0A1B0GVW2|A0A1B0GVW2_HUMAN,tr|A0A1B0GUE9|A0A1B0GUE9_HUMAN" 4 875.5208 0.35 14448 14369 2 875.521325 438.7677 Dedicator of cytokinesis protein 7 OS=Homo sapiens OX=9606 GN=DOCK7 PE=1 SV=4 5.84 2870.8 - 445327 - - - 0.6351 - 1.12 0.112 - 79.3 2 2 0 0.0006 8 0 0 0 5.56E+06 1.59E+07 - - - 0.0754 0.9998 221125_WJC_METTL3_EV_vs_WT_F02.14372.14372.2 0.000103 14-Jul K.LVWVPSDK[136.11].S "sp|P35579|MYH9_HUMAN,tr|Q5BKV1|Q5BKV1_HUMAN,tr|B1AH99|B1AH99_HUMAN" 3 950.5317 0.85 14449 14372 2 950.531508 476.2731 Myosin-9 OS=Homo sapiens OX=9606 GN=MYH9 PE=1 SV=4 5.84 2871.2 - 5.53E+06 - - - -0.1683 - 1.414 0.525 - 195 1 2 0 -0.0002 8 0 0 0 1.48E+08 1.74E+08 - - - 3.9634 0.9995 221125_WJC_METTL3_EV_vs_WT_F02.14373.14373.2 0.00723 14-Jul K.LVWVPSDK.S "sp|P35579|MYH9_HUMAN,tr|Q5BKV1|Q5BKV1_HUMAN,tr|B1AH99|B1AH99_HUMAN" 3 942.5175 0.86 14450 14373 2 942.516408 472.266 Myosin-9 OS=Homo sapiens OX=9606 GN=MYH9 PE=1 SV=4 5.84 2871.2 - 4.56E+06 - - - -1.1246 - 1.344 0.456 - 192.1 1 2 0 -0.0011 8 0 0 0 1.49E+08 1.73E+08 - - - 3.3004 0.9798 221125_WJC_METTL3_EV_vs_WT_F02.14378.14378.2 1.8 12-Jul K.SLLFNAR.L "sp|Q6KC79|NIPBL_HUMAN,tr|A0A590UJS4|A0A590UJS4_HUMAN" 2 819.4603 1.54 14453 14378 2 819.459438 410.7374 Nipped-B-like protein OS=Homo sapiens OX=9606 GN=NIPBL PE=1 SV=2 9.47 2871.8 - 2.11E+06 - - - -1.036 - 1.192 0.092 - 196.9 1 2 0 -0.0008 7 0 0 0 1.02E+08 6.62E+07 - - - 0.2767 0.956 221125_WJC_METTL3_EV_vs_WT_F02.14380.14380.2 0.0751 16-Jun R.EMGVIAAMR[166.11].D "sp|O75534|CSDE1_HUMAN,tr|E9PLT0|E9PLT0_HUMAN" 2 986.4917 0.86 14455 14380 2 986.487313 494.2531 Cold shock domain-containing protein E1 OS=Homo sapiens OX=9606 GN=CSDE1 PE=1 SV=2 6.1 2871.9 - 1.26E+06 - - - -4.4238 - 1.053 0.291 - 120.8 1 2 0 -0.0044 9 0 0 0 2.01E+07 2.35E+07 - - - 1.3384 0.9831 221125_WJC_METTL3_EV_vs_WT_F02.14384.14384.2 3.24 12-Jun K.TIADIIR.T "sp|P49368|TCPG_HUMAN,sp|Q16878|CDO1_HUMAN,tr|E9PM09|E9PM09_HUMAN,tr|E9PRC8|E9PRC8_HUMAN,tr|Q5SZX9|Q5SZX9_HUMAN,tr|Q5SZX6|Q5SZX6_HUMAN" 6 800.4756 0.23 14457 14384 2 800.473875 401.2451 T-complex protein 1 subunit gamma OS=Homo sapiens OX=9606 GN=CCT3 PE=1 SV=4 5.5 2872.4 - 1.76E+07 - - - -2.1587 - 1.124 0.196 - 129.3 1 2 0 -0.0017 7 0 0 0 3.92E+08 1.74E+09 - - - 0.8585 0.9966 221125_WJC_METTL3_EV_vs_WT_F02.14386.14386.2 2.22 12-Jun R.LSFSGLR.A "sp|Q15149|PLEC_HUMAN,tr|H0YDN1|H0YDN1_HUMAN" 2 778.4337 2.4 14459 14386 2 778.433346 390.2241 Plectin OS=Homo sapiens OX=9606 GN=PLEC PE=1 SV=3 9.75 2872.6 - 1.70E+06 - - - -0.5036 - 1.401 0.176 - 98.5 1 2 0 -0.0004 7 0 0 0 9.23E+07 3.84E+07 - - - 1.4092 0.8176 221125_WJC_METTL3_EV_vs_WT_F02.14387.14387.2 0.133 16-Aug K.VTSLILIRN.N "sp|A2VDJ0|T131L_HUMAN,tr|H0Y2M0|H0Y2M0_HUMAN" 2 1027.639 999 14460 14387 2 1027.63907 514.8268 Transmembrane protein 131-like OS=Homo sapiens OX=9606 GN=TMEM131L PE=1 SV=2 9.72 2872.6 - 1.68E+06 - - - 0.0876 - 1.804 0.078 - 177.6 1 1 0 0.0001 9 0 0 0 6.01E+07 0.00E+00 - - - 1.324 0.9974 221125_WJC_METTL3_EV_vs_WT_F02.14388.14388.2 0.0309 16-Jun R.EMGVIAAMR.D "sp|O75534|CSDE1_HUMAN,tr|E9PLT0|E9PLT0_HUMAN" 2 976.4834 0.73 14461 14388 2 976.484397 489.249 Cold shock domain-containing protein E1 OS=Homo sapiens OX=9606 GN=CSDE1 PE=1 SV=2 6.1 2872.7 - 843398 - - - 1.0138 - 1.212 0.3 - 102 1 2 0 0.001 9 0 0 0 1.75E+07 2.40E+07 - - - 1.8127 0.9986 221125_WJC_METTL3_EV_vs_WT_F02.14389.14389.2 0.395 14-Aug K.SAFPFSDK.L sp|Q14677|EPN4_HUMAN 1 897.4232 0.65 14462 14389 2 897.422998 449.7189 Clathrin interactor 1 OS=Homo sapiens OX=9606 GN=CLINT1 PE=1 SV=1 5.55 2872.9 - 708575 - - - -0.2619 - 1.413 0.269 - 154 1 2 0 -0.0002 8 0 0 0 2.29E+07 3.54E+07 - - - 2.0704 0.9993 221125_WJC_METTL3_EV_vs_WT_F02.14396.14396.2 1.16E-05 16-Sep K.YFSMTEVDR.L "sp|P05089|ARGI1_HUMAN,tr|A0A5F9ZGN6|A0A5F9ZGN6_HUMAN,tr|A0A5F9ZH78|A0A5F9ZH78_HUMAN" 3 1146.5016 76.51 14467 14396 2 1146.497562 574.2581 Arginase-1 OS=Homo sapiens OX=9606 GN=ARG1 PE=1 SV=2 4.37 2873.7 - 2.29E+06 - - - -3.4871 - 1.658 0.602 - 246.3 1 2 0 -0.004 9 0 0 0 8.00E+07 1.05E+06 - - - 4.9489 0.9997 221125_WJC_METTL3_EV_vs_WT_F02.14398.14398.2 0.000215 18-Nov K.LAEQYDAFVK.F sp|Q53H80|AKIR2_HUMAN 1 1182.5921 1.38 14469 14398 2 1182.593976 592.3033 Akirin-2 OS=Homo sapiens OX=9606 GN=AKIRIN2 PE=1 SV=2 4.37 2873.9 - 938981 - - - 1.5948 - 2.389 0.427 - 399.8 1 2 0 0.0019 10 0 0 0 3.64E+07 2.64E+07 - - - 4.6251 0.9503 221125_WJC_METTL3_EV_vs_WT_F02.14400.14400.2 3.97 12-May K.LLWTTSR.V "sp|P35222|CTNB1_HUMAN,sp|P14923|PLAK_HUMAN,tr|A0A2R8Y6G0|A0A2R8Y6G0_HUMAN,tr|A0A2R8Y5C3|A0A2R8Y5C3_HUMAN,tr|A0A2R8YCH5|A0A2R8YCH5_HUMAN,tr|A0A2R8Y543|A0A2R8Y543_HUMAN,tr|A0A2R8Y750|A0A2R8Y750_HUMAN,tr|B4DGU4|B4DGU4_HUMAN,tr|A0A2R8Y5A3|A0A2R8Y5A3_HUMAN,tr|A0A2R8Y804|A0A2R8Y804_HUMAN,tr|A0A2R8Y5Z1|A0A2R8Y5Z1_HUMAN,tr|A0A2R8Y7Z0|A0A2R8Y7Z0_HUMAN" 12 875.4865 3.34 14471 14400 2 875.486833 438.7505 Catenin beta-1 OS=Homo sapiens OX=9606 GN=CTNNB1 PE=1 SV=1 9.75 2874 - 547632 - - - 0.3781 - 0.948 0.117 - 61.1 2 2 0 0.0003 7 0 0 0 1.60E+08 4.80E+07 - - - -0.3986 0.9142 221125_WJC_METTL3_EV_vs_WT_F02.14401.14401.2 2.32 12-Jun R.SYYFPVK[136.11].N sp|Q15393|SF3B3_HUMAN 1 910.468 1.46 14472 14401 2 910.467583 456.2413 Splicing factor 3B subunit 3 OS=Homo sapiens OX=9606 GN=SF3B3 PE=1 SV=4 8.22 2874.1 - 506221 - - - -0.4635 - 0.966 0.039 - 132.5 1 2 0 -0.0004 7 0 0 0 3.58E+08 2.45E+08 - - - -0.7807 0.9989 221125_WJC_METTL3_EV_vs_WT_F02.14403.14403.2 0.0582 14-Jul K.GYFDQELK.A "sp|Q13405|RM49_HUMAN,tr|H0YDP7|H0YDP7_HUMAN" 2 998.4709 0.84 14473 14403 2 998.470885 500.2427 "39S ribosomal protein L49, mitochondrial OS=Homo sapiens OX=9606 GN=MRPL49 PE=1 SV=1" 4.37 2874.4 - 1.98E+06 - - - -0.027 - 1.287 0.339 - 162.1 1 2 0 0 8 0 0 0 4.48E+07 5.31E+07 - - - 2.3058 0.9998 221125_WJC_METTL3_EV_vs_WT_F02.14406.14406.2 0.0173 26-Dec R.LVVPASQC[160.03]GSLIGK[136.11].G "sp|P57721|PCBP3_HUMAN,sp|Q15366|PCBP2_HUMAN,tr|F8W1G6|F8W1G6_HUMAN,tr|E9PFP8|E9PFP8_HUMAN,tr|J3QT27|J3QT27_HUMAN,tr|F8VZX2|F8VZX2_HUMAN,tr|F8W0G4|F8W0G4_HUMAN,tr|F8VXH9|F8VXH9_HUMAN,tr|H3BRU6|H3BRU6_HUMAN,tr|H3BND9|H3BND9_HUMAN" 10 1435.7948 1.17 14475 14406 2 1435.7955 718.9047 Poly(rC)-binding protein 3 OS=Homo sapiens OX=9606 GN=PCBP3 PE=1 SV=2 8.22 2874.7 - 699383 - - - 0.4625 - 2.085 0.42 - 304.3 1 2 0 0.0007 14 0 0 0 1.20E+08 1.03E+08 - - - 3.9868 0.9998 221125_WJC_METTL3_EV_vs_WT_F02.14407.14407.2 5.71E-05 22-Nov K.LGSIAIQGAIEK.A "sp|P24752|THIL_HUMAN,tr|A0A5F9ZHL7|A0A5F9ZHL7_HUMAN,tr|A0A5F9ZHJ7|A0A5F9ZHJ7_HUMAN,tr|A0A5F9ZHH9|A0A5F9ZHH9_HUMAN,tr|A0A5F9ZHL1|A0A5F9ZHL1_HUMAN,tr|E9PRQ6|E9PRQ6_HUMAN,tr|H0YEL7|H0YEL7_HUMAN" 7 1198.6921 1.49 14476 14407 2 1198.692292 600.3533 "Acetyl-CoA acetyltransferase, mitochondrial OS=Homo sapiens OX=9606 GN=ACAT1 PE=1 SV=1" 6 2874.7 - 2.60E+06 - - - 0.1285 - 2.39 0.415 - 261.1 1 2 0 0.0002 12 0 0 0 4.54E+08 3.06E+08 - - - 4.3987 0.9533 221125_WJC_METTL3_EV_vs_WT_F02.14408.14408.2 2.66 14-May R.IFTNLYGR.H "sp|P49821|NDUV1_HUMAN,tr|G3V0I5|G3V0I5_HUMAN,tr|E9PQP1|E9PQP1_HUMAN,tr|E9PPS5|E9PPS5_HUMAN" 4 982.5236 0.24 14477 14408 2 982.523213 492.2691 "NADH dehydrogenase [ubiquinone] flavoprotein 1, mitochondrial OS=Homo sapiens OX=9606 GN=NDUFV1 PE=1 SV=4" 8.75 2874.8 - 966925 - - - -0.4102 - 1.209 0.058 - 56 9 2 0 -0.0004 8 0 0 0 1.77E+07 7.34E+07 - - - -0.3846 0.9997 221125_WJC_METTL3_EV_vs_WT_F02.14412.14412.2 5.47E-05 22-Dec K.LGSIAIQGAIEK[136.11].A "sp|P24752|THIL_HUMAN,tr|A0A5F9ZHL7|A0A5F9ZHL7_HUMAN,tr|A0A5F9ZHJ7|A0A5F9ZHJ7_HUMAN,tr|A0A5F9ZHH9|A0A5F9ZHH9_HUMAN,tr|A0A5F9ZHL1|A0A5F9ZHL1_HUMAN,tr|E9PRQ6|E9PRQ6_HUMAN,tr|H0YEL7|H0YEL7_HUMAN" 7 1206.7063 1.45 14479 14412 2 1206.70701 604.3604 "Acetyl-CoA acetyltransferase, mitochondrial OS=Homo sapiens OX=9606 GN=ACAT1 PE=1 SV=1" 6 2875.4 - 3.77E+06 - - - 0.5569 - 2.389 0.324 - 327.2 1 2 0 0.0007 12 0 0 0 4.43E+08 3.05E+08 - - - 3.7253 0.9992 221125_WJC_METTL3_EV_vs_WT_F02.14415.14415.2 0.00105 20-Oct K.LYEQILAENEK[136.11].L "sp|O14974|MYPT1_HUMAN,tr|H0YIM2|H0YIM2_HUMAN,tr|H0YIS3|H0YIS3_HUMAN,tr|A0A0U1RQZ1|A0A0U1RQZ1_HUMAN" 4 1356.7016 0.37 14482 14415 2 1356.705688 679.3581 Protein phosphatase 1 regulatory subunit 12A OS=Homo sapiens OX=9606 GN=PPP1R12A PE=1 SV=1 4.25 2875.7 - 234445 - - - 2.9785 - 2.003 0.455 - 247.6 1 2 0 0.004 11 0 0 0 2.85E+06 7.70E+06 - - - 4.2795 0.9911 221125_WJC_METTL3_EV_vs_WT_F02.14419.14419.2 0.0375 20-Aug K.VPASPLPGLER.K "sp|Q7KZI7|MARK2_HUMAN,tr|A0A0A0MRU9|A0A0A0MRU9_HUMAN,tr|E7ETY4|E7ETY4_HUMAN,tr|A0A7I2YQR3|A0A7I2YQR3_HUMAN,tr|E9PC69|E9PC69_HUMAN,tr|A0A7I2V3R3|A0A7I2V3R3_HUMAN" 6 1134.6397 5.74 14484 14419 2 1134.640722 568.3271 Serine\threonine-protein kinase MARK2 OS=Homo sapiens OX=9606 GN=MARK2 PE=1 SV=2 5.97 2876.2 - 851368 - - - 0.8937 - 1.647 0.081 - 190.6 2 2 0 0.001 11 0 0 0 3.65E+08 6.35E+07 - - - 0.8543 0.9973 221125_WJC_METTL3_EV_vs_WT_F02.14424.14424.2 0.0437 16-Sep K.FEEMIQQIK[136.11].E "sp|P48643|TCPE_HUMAN,tr|E9PCA1|E9PCA1_HUMAN,tr|B7ZAR1|B7ZAR1_HUMAN,tr|E7ENZ3|E7ENZ3_HUMAN" 4 1172.5991 0.61 14487 14424 2 1172.601571 587.3068 T-complex protein 1 subunit epsilon OS=Homo sapiens OX=9606 GN=CCT5 PE=1 SV=1 4.53 2876.8 - 1.39E+06 - - - 2.1107 - 1.484 0.287 - 229.8 1 2 0 0.0025 9 0 0 0 3.47E+08 5.66E+08 - - - 2.302 0.9158 221125_WJC_METTL3_EV_vs_WT_F02.14426.14426.2 0.00868 14-Jun K.ELGITALH.L "sp|P62263|RS14_HUMAN,tr|A0A2R8Y811|A0A2R8Y811_HUMAN,tr|E5RH77|E5RH77_HUMAN" 3 852.4705 - 14489 14426 2 852.470281 427.2425 40S ribosomal protein S14 OS=Homo sapiens OX=9606 GN=RPS14 PE=1 SV=3 5.24 2877 - 1.65E+06 - - - -0.278 - 1.264 0.306 - 103 1 1 0 -0.0002 8 0 0 0 - - - - - 2.0076 0.9997 221125_WJC_METTL3_EV_vs_WT_F02.14432.14432.2 0.000128 14-Jul R.AFFSEVER[166.11].R "sp|Q9UQ80|PA2G4_HUMAN,tr|F8VR77|F8VR77_HUMAN" 2 993.4795 0.11 14493 14432 2 993.480463 497.747 Proliferation-associated protein 2G4 OS=Homo sapiens OX=9606 GN=PA2G4 PE=1 SV=3 4.53 2877.7 - 6.49E+06 - - - 0.9532 - 1.49 0.494 - 143 1 2 0 0.0009 8 0 0 0 6.50E+07 5.87E+08 - - - 3.8921 0.9999 221125_WJC_METTL3_EV_vs_WT_F02.14433.14433.2 7.95E-06 20-Nov K.YGQISEVVVVK[136.11].D "sp|Q14011|CIRBP_HUMAN,tr|K7ER40|K7ER40_HUMAN,tr|K7ENX8|K7ENX8_HUMAN,tr|K7EJV1|K7EJV1_HUMAN,tr|K7EJV5|K7EJV5_HUMAN,tr|K7ELT6|K7ELT6_HUMAN,tr|K7EMY9|K7EMY9_HUMAN,tr|K7ELV6|K7ELV6_HUMAN,tr|K7EQR7|K7EQR7_HUMAN,tr|K7EPM4|K7EPM4_HUMAN,tr|D6W5Y5|D6W5Y5_HUMAN" 11 1227.6954 0.95 14494 14433 2 1227.695812 614.855 Cold-inducible RNA-binding protein OS=Homo sapiens OX=9606 GN=CIRBP PE=1 SV=1 6 2877.8 - 5.65E+06 - - - 0.3038 - 2.452 0.555 - 356.2 1 2 0 0.0004 11 0 0 0 1.95E+09 2.05E+09 - - - 5.5665 0.9998 221125_WJC_METTL3_EV_vs_WT_F02.14434.14434.2 0.0177 16-Oct K.FEEMIQQIK.E "sp|P48643|TCPE_HUMAN,tr|E9PCA1|E9PCA1_HUMAN,tr|B7ZAR1|B7ZAR1_HUMAN,tr|E7ENZ3|E7ENZ3_HUMAN" 4 1164.5849 0.61 14495 14434 2 1164.585538 583.2997 T-complex protein 1 subunit epsilon OS=Homo sapiens OX=9606 GN=CCT5 PE=1 SV=1 4.53 2877.8 - 1.87E+06 - - - 0.5513 - 1.964 0.41 - 257.2 1 2 0 0.0006 9 0 0 0 3.47E+08 5.66E+08 - - - 4.0218 0.9974 221125_WJC_METTL3_EV_vs_WT_F02.14435.14435.2 0.244 12-Jul K.ILQVSFK.T sp|Q15717|ELAV1_HUMAN 1 833.5011 1.27 14496 14435 2 833.501564 417.7578 ELAV-like protein 1 OS=Homo sapiens OX=9606 GN=ELAVL1 PE=1 SV=2 8.75 2878 - 1.22E+06 - - - 0.5687 - 1.58 0.158 - 122.3 1 2 0 0.0005 7 0 0 0 6.91E+08 5.45E+08 - - - 1.6572 0.9978 221125_WJC_METTL3_EV_vs_WT_F02.14436.14436.2 0.032 12-Jun K.YC[160.03]SYFLK.N sp|O95628|CNOT4_HUMAN 1 979.4473 1.84 14497 14436 2 979.448887 490.7309 CCR4-NOT transcription complex subunit 4 OS=Homo sapiens OX=9606 GN=CNOT4 PE=1 SV=3 8.18 2878 - 1.04E+06 - - - 1.5795 - 1.419 0.278 - 96 1 2 0 0.0015 7 0 0 0 2.49E+07 1.35E+07 - - - 2.2027 0.9977 221125_WJC_METTL3_EV_vs_WT_F02.14439.14439.2 0.259 14-Aug K.FEALDIEK[136.11].A "sp|Q6WCQ1|MPRIP_HUMAN,tr|A0A494BZV2|A0A494BZV2_HUMAN,tr|A0A1W2PPU9|A0A1W2PPU9_HUMAN,tr|J3KSW8|J3KSW8_HUMAN" 4 971.5055 0.6 14498 14439 2 971.504248 486.76 Myosin phosphatase Rho-interacting protein OS=Homo sapiens OX=9606 GN=MPRIP PE=1 SV=3 4.14 2878.4 - 487391 - - - -1.3021 - 1.528 0.22 - 116.4 1 2 0 -0.0013 8 0 0 0 8.11E+06 1.34E+07 - - - 1.9442 0.9997 221125_WJC_METTL3_EV_vs_WT_F02.14440.14440.2 2.13E-05 18-Aug K.YLYSSEDYIK.S sp|Q13200|PSMD2_HUMAN 1 1279.5972 0.42 14499 14440 2 1279.598542 640.8059 26S proteasome non-ATPase regulatory subunit 2 OS=Homo sapiens OX=9606 GN=PSMD2 PE=1 SV=3 4.37 2878.6 - 675362 - - - 1.0214 - 1.548 0.487 - 122.2 1 2 0 0.0013 10 0 0 0 2.13E+07 5.03E+07 - - - 3.8573 0.9204 221125_WJC_METTL3_EV_vs_WT_F02.14443.14443.2 0.000298 24-Aug S.AVPELATDPELEK[136.11].K "sp|Q86U44|MTA70_HUMAN,tr|B4E349|B4E349_HUMAN,tr|F5H6D8|F5H6D8_HUMAN,tr|H0YFV6|H0YFV6_HUMAN,tr|B4DTN4|B4DTN4_HUMAN" 5 1418.7384 0.01 14502 14443 2 1418.734709 710.3765 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 4 2878.9 - 256039 - - - -2.6199 - 1.639 0.39 - 138.4 1 1 0 -0.0037 13 0 0 0 5.85E+06 5.18E+08 - - - 3.1885 0.9998 221125_WJC_METTL3_EV_vs_WT_F02.14445.14445.2 0.00952 16-Sep K.TLLDIDNTR.M sp|P35527|K1C9_HUMAN 1 1059.556 2910.49 14503 14445 2 1059.555776 530.7853 "Keratin, type I cytoskeletal 9 OS=Homo sapiens OX=9606 GN=KRT9 PE=1 SV=3" 4.21 2879.1 - 1.54E+08 - - - -0.2473 - 1.825 0.486 - 221.6 1 2 0 -0.0003 9 0 0 0 2.04E+10 6.99E+06 - - - 4.3709 0.9946 221125_WJC_METTL3_EV_vs_WT_F02.14447.14447.2 0.135 12-Aug K.ILQVSFK[136.11].T sp|Q15717|ELAV1_HUMAN 1 841.5153 1.27 14504 14447 2 841.515076 421.7649 ELAV-like protein 1 OS=Homo sapiens OX=9606 GN=ELAVL1 PE=1 SV=2 8.75 2879.3 - 3.54E+06 - - - -0.2543 - 1.637 0.078 - 174.7 2 2 0 -0.0002 7 0 0 0 6.91E+08 5.45E+08 - - - 1.0442 0.9993 221125_WJC_METTL3_EV_vs_WT_F02.14450.14450.2 0.0333 12-Jul R.YYTVFDR.D "sp|P07339|CATD_HUMAN,tr|A0A1B0GW44|A0A1B0GW44_HUMAN,tr|A0A1B0GVD5|A0A1B0GVD5_HUMAN,tr|A0A1B0GV23|A0A1B0GV23_HUMAN,tr|C9JH19|C9JH19_HUMAN,tr|H7C469|H7C469_HUMAN,tr|A0A1B0GWE8|A0A1B0GWE8_HUMAN,tr|A0A1B0GVP3|A0A1B0GVP3_HUMAN,tr|F8W787|F8W787_HUMAN" 9 962.4498 14.29 14507 14450 2 962.449487 482.2322 Cathepsin D OS=Homo sapiens OX=9606 GN=CTSD PE=1 SV=1 5.83 2879.6 - 609354 - - - -0.3065 - 1.534 0.311 - 142.4 1 2 0 -0.0003 7 0 0 0 9.76E+07 6.83E+06 - - - 2.6937 0.9996 221125_WJC_METTL3_EV_vs_WT_F02.14453.14453.2 0.0221 16-Aug K.AGLVDDFEK[136.11].K "sp|O75947|ATP5H_HUMAN,tr|F5H608|F5H608_HUMAN" 2 1000.4957 2.47 14508 14453 2 1000.496807 501.2551 "ATP synthase subunit d, mitochondrial OS=Homo sapiens OX=9606 GN=ATP5PD PE=1 SV=3" 4.03 2880 - 3.11E+06 - - - 1.1304 - 2.045 0.357 - 165.5 1 2 0 0.0011 9 0 0 0 5.38E+08 2.18E+08 - - - 3.7471 0.9969 221125_WJC_METTL3_EV_vs_WT_F02.14461.14461.2 0.00117 18-Oct R.LQELAELEAK[136.11].K sp|Q9H5V9|STEEP_HUMAN 1 1150.6325 0.9 14514 14461 2 1150.628337 576.3235 STING ER exit protein OS=Homo sapiens OX=9606 GN=STEEP1 PE=1 SV=1 4.25 2880.9 - 1.06E+06 - - - -3.6215 - 2.287 0.245 - 253.7 1 2 0 -0.0042 10 0 0 0 1.74E+07 1.93E+07 - - - 3.1583 0.9994 221125_WJC_METTL3_EV_vs_WT_F02.14463.14463.2 0.0104 12-Jul R.VVFQEFR[166.11].Q sp|P35579|MYH9_HUMAN 1 933.4948 0.91 14516 14463 2 933.493838 467.7547 Myosin-9 OS=Homo sapiens OX=9606 GN=MYH9 PE=1 SV=4 5.97 2881.1 - 4.50E+06 - - - -1.0005 - 1.484 0.38 - 245.3 1 2 0 -0.0009 7 0 0 0 2.76E+08 3.04E+08 - - - 3.0981 0.9999 221125_WJC_METTL3_EV_vs_WT_F02.14466.14466.2 3.55E-06 18-Dec R.FPGQLNADLR.K "sp|P04350|TBB4A_HUMAN,sp|Q9BVA1|TBB2B_HUMAN,sp|A6NNZ2|TBB8B_HUMAN,sp|P07437|TBB5_HUMAN,sp|Q13509|TBB3_HUMAN,sp|Q13885|TBB2A_HUMAN,sp|P68371|TBB4B_HUMAN,sp|Q9BUF5|TBB6_HUMAN,sp|Q3ZCM7|TBB8_HUMAN,sp|Q9H4B7|TBB1_HUMAN,tr|M0R2D3|M0R2D3_HUMAN,tr|A0A0B4J269|A0A0B4J269_HUMAN,tr|Q5ST81|Q5ST81_HUMAN,tr|Q5JP53|Q5JP53_HUMAN,tr|K7ESM5|K7ESM5_HUMAN,tr|A0A075B736|A0A075B736_HUMAN,tr|G3V2A3|G3V2A3_HUMAN,tr|Q5SQY0|Q5SQY0_HUMAN" 18 1129.588 0.76 14518 14466 2 1129.586929 565.8013 Tubulin beta-4A chain OS=Homo sapiens OX=9606 GN=TUBB4A PE=1 SV=2 5.84 2881.4 - 5.93E+06 - - - -0.9543 - 2.395 0.562 - 541.4 1 2 0 -0.0011 10 0 0 0 3.00E+08 3.94E+08 - - - 5.6295 0.9967 221125_WJC_METTL3_EV_vs_WT_F02.14469.14469.2 0.00169 16-Sep K.FGDMSYSIR.H "sp|Q16890|TPD53_HUMAN,tr|E9PNK6|E9PNK6_HUMAN" 2 1074.4804 3.62 14520 14469 2 1074.475287 538.2475 Tumor protein D53 OS=Homo sapiens OX=9606 GN=TPD52L1 PE=1 SV=1 5.84 2881.7 - 744903 - - - -4.7874 - 1.892 0.43 - 178.8 1 2 0 -0.0051 9 0 0 0 1.45E+07 4.02E+06 - - - 4.0601 0.9889 221125_WJC_METTL3_EV_vs_WT_F02.14473.14473.2 0.342 14-Jul K.QLFDQVVK[136.11].T "sp|P15311|EZRI_HUMAN,sp|P26038|MOES_HUMAN,sp|P35241|RADI_HUMAN,tr|A0A2R8Y5S7|A0A2R8Y5S7_HUMAN,tr|E7EQR4|E7EQR4_HUMAN,tr|E9PQ82|E9PQ82_HUMAN,tr|A0A2R8Y7M3|A0A2R8Y7M3_HUMAN,tr|E9PNV3|E9PNV3_HUMAN,tr|V9GZ54|V9GZ54_HUMAN" 9 983.5531 0.57 14522 14473 2 983.551768 492.7838 Ezrin OS=Homo sapiens OX=9606 GN=EZR PE=1 SV=4 5.84 2882.2 - 4.89E+06 - - - -1.3868 - 0.947 0.261 - 119.7 1 2 0 -0.0014 8 0 0 0 6.77E+07 1.18E+08 - - - 0.8041 0.9991 221125_WJC_METTL3_EV_vs_WT_F02.14475.14475.2 0.0162 20-Aug K.AVDEAADALLK.A "sp|Q16891|MIC60_HUMAN,tr|B9A067|B9A067_HUMAN,tr|C9J406|C9J406_HUMAN,tr|H7C463|H7C463_HUMAN" 4 1114.587 1.39 14524 14475 2 1114.584797 558.3008 MICOS complex subunit MIC60 OS=Homo sapiens OX=9606 GN=IMMT PE=1 SV=1 4.03 2882.4 - 5.83E+06 - - - -1.9801 - 1.841 0.332 - 126.3 1 2 0 -0.0022 11 0 0 0 1.08E+09 7.72E+08 - - - 3.1435 0.9988 221125_WJC_METTL3_EV_vs_WT_F02.14476.14476.2 0.0601 14-Jun R.MC[160.03]LVEIEK.A "sp|P28331|NDUS1_HUMAN,tr|F8WDL5|F8WDL5_HUMAN,tr|C9JPQ5|C9JPQ5_HUMAN" 3 1020.4984 1.83 14525 14476 2 1020.497272 511.2565 "NADH-ubiquinone oxidoreductase 75 kDa subunit, mitochondrial OS=Homo sapiens OX=9606 GN=NDUFS1 PE=1 SV=3" 4.53 2882.5 - 1.79E+06 - - - -1.0946 - 1.554 0.28 - 125.5 1 2 0 -0.0011 8 0 0 0 3.62E+07 1.98E+07 - - - 2.4383 0.9788 221125_WJC_METTL3_EV_vs_WT_F02.14479.14479.2 0.00804 14-Aug R.MC[160.03]LVEIEK[136.11].A "sp|P28331|NDUS1_HUMAN,tr|F8WDL5|F8WDL5_HUMAN,tr|C9JPQ5|C9JPQ5_HUMAN" 3 1028.5126 1.89 14528 14479 2 1028.506744 515.2636 "NADH-ubiquinone oxidoreductase 75 kDa subunit, mitochondrial OS=Homo sapiens OX=9606 GN=NDUFS1 PE=1 SV=3" 4.53 2882.8 - 1.14E+06 - - - -5.683 - 1.826 0.25 - 245.9 1 2 0 -0.0058 8 0 0 0 3.49E+07 1.85E+07 - - - 2.7017 0.9994 221125_WJC_METTL3_EV_vs_WT_F02.14482.14482.2 7.44E-05 18-Oct R.FPGQLNADLR[166.11].K "sp|P04350|TBB4A_HUMAN,sp|Q9BVA1|TBB2B_HUMAN,sp|A6NNZ2|TBB8B_HUMAN,sp|P07437|TBB5_HUMAN,sp|Q13509|TBB3_HUMAN,sp|Q13885|TBB2A_HUMAN,sp|P68371|TBB4B_HUMAN,sp|Q9BUF5|TBB6_HUMAN,sp|Q3ZCM7|TBB8_HUMAN,sp|Q9H4B7|TBB1_HUMAN,tr|M0R2D3|M0R2D3_HUMAN,tr|A0A0B4J269|A0A0B4J269_HUMAN,tr|Q5ST81|Q5ST81_HUMAN,tr|Q5JP53|Q5JP53_HUMAN,tr|K7ESM5|K7ESM5_HUMAN,tr|A0A075B736|A0A075B736_HUMAN,tr|G3V2A3|G3V2A3_HUMAN,tr|Q5SQY0|Q5SQY0_HUMAN" 18 1139.5963 0.76 14529 14482 2 1139.593325 570.8054 Tubulin beta-4A chain OS=Homo sapiens OX=9606 GN=TUBB4A PE=1 SV=2 5.84 2883.2 - 8.64E+06 - - - -2.5904 - 1.901 0.467 - 323.1 1 2 0 -0.003 10 0 0 0 3.06E+08 4.02E+08 - - - 4.2824 0.9989 221125_WJC_METTL3_EV_vs_WT_F02.14484.14484.2 0.00329 18-Sep R.SLPLVQVDEK.G sp|Q92615|LAR4B_HUMAN 1 1126.6234 1.05 14531 14484 2 1126.619797 564.319 La-related protein 4B OS=Homo sapiens OX=9606 GN=LARP4B PE=1 SV=3 4.37 2883.3 - 1.06E+07 - - - -3.1892 - 1.785 0.45 - 308.7 1 2 0 -0.0036 10 0 0 0 3.80E+08 3.61E+08 - - - 3.9809 0.9992 221125_WJC_METTL3_EV_vs_WT_F02.14485.14485.2 0.0107 16-Jul R.GTYDILVTK.D "sp|P13861|KAP2_HUMAN,tr|H7C1L0|H7C1L0_HUMAN" 2 1008.5492 1.8 14532 14485 2 1008.547882 505.2819 cAMP-dependent protein kinase type II-alpha regulatory subunit OS=Homo sapiens OX=9606 GN=PRKAR2A PE=1 SV=2 5.83 2883.4 - 2.28E+06 - - - -1.2691 - 1.297 0.417 - 93.8 1 2 0 -0.0013 9 0 0 0 2.50E+08 1.39E+08 - - - 2.8729 0.9994 221125_WJC_METTL3_EV_vs_WT_F02.14489.14489.2 8.74E-06 13/18 K.LAANAFLAQR.L sp|O60701|UGDH_HUMAN 1 1073.5982 0.77 14534 14489 2 1073.594686 537.8064 UDP-glucose 6-dehydrogenase OS=Homo sapiens OX=9606 GN=UGDH PE=1 SV=1 9.75 2883.9 - 971296 - - - -3.2526 - 2.52 0.464 - 553.7 1 2 0 -0.0035 10 0 0 0 6.56E+07 8.56E+07 - - - 5.0469 0.9997 221125_WJC_METTL3_EV_vs_WT_F02.14495.14495.2 0.000754 20-Nov R.LDIDSPPITAR[166.11].N "sp|P14618|KPYM_HUMAN,tr|H3BQ34|H3BQ34_HUMAN,tr|H3BTJ2|H3BTJ2_HUMAN,tr|B4DNK4|B4DNK4_HUMAN,tr|A0A804F6T5|A0A804F6T5_HUMAN,tr|H3BT25|H3BT25_HUMAN,tr|H3BQZ3|H3BQZ3_HUMAN,tr|H3BUW1|H3BUW1_HUMAN,tr|H3BTN5|H3BTN5_HUMAN,tr|H3BN34|H3BN34_HUMAN,tr|A0A804F729|A0A804F729_HUMAN,tr|H3BU13|H3BU13_HUMAN" 12 1206.6484 1.14 14538 14495 2 1206.646659 604.3315 Pyruvate kinase PKM OS=Homo sapiens OX=9606 GN=PKM PE=1 SV=4 4.21 2884.6 - 3.12E+06 - - - -1.4196 - 2.113 0.39 - 326 1 2 0 -0.0017 11 0 0 0 1.95E+08 1.70E+08 - - - 3.9448 0.9998 221125_WJC_METTL3_EV_vs_WT_F02.14496.14496.2 0.00419 20-Oct R.LDIDSPPITAR.N "sp|P14618|KPYM_HUMAN,tr|H3BQ34|H3BQ34_HUMAN,tr|H3BTJ2|H3BTJ2_HUMAN,tr|B4DNK4|B4DNK4_HUMAN,tr|A0A804F6T5|A0A804F6T5_HUMAN,tr|H3BT25|H3BT25_HUMAN,tr|H3BQZ3|H3BQZ3_HUMAN,tr|H3BUW1|H3BUW1_HUMAN,tr|H3BTN5|H3BTN5_HUMAN,tr|H3BN34|H3BN34_HUMAN,tr|A0A804F729|A0A804F729_HUMAN,tr|H3BU13|H3BU13_HUMAN" 12 1196.6401 0.28 14539 14496 2 1196.639255 599.3273 Pyruvate kinase PKM OS=Homo sapiens OX=9606 GN=PKM PE=1 SV=4 4.21 2884.6 - 4.45E+06 - - - -0.7078 - 2.169 0.399 - 265.3 1 2 0 -0.0008 11 0 0 0 2.59E+08 9.42E+08 - - - 4.0823 0.9928 221125_WJC_METTL3_EV_vs_WT_F02.14497.14497.2 0.154 12-May K.ADEWLMK.N "sp|P35580|MYH10_HUMAN,sp|P35579|MYH9_HUMAN" 2 891.416 0.82 14540 14497 2 891.416225 446.7153 Myosin-10 OS=Homo sapiens OX=9606 GN=MYH10 PE=1 SV=3 4.37 2884.7 - 1.70E+06 - - - 0.2087 - 1.123 0.197 - 98.2 1 2 0 0.0002 7 0 0 0 1.10E+08 1.35E+08 - - - 0.8635 0.9994 221125_WJC_METTL3_EV_vs_WT_F02.14498.14498.2 0.00705 18-Oct K.GSPILLGVSK.G sp|Q9NZH6|IL37_HUMAN 1 969.5859 3.04 14541 14498 2 969.586428 485.8002 Interleukin-37 OS=Homo sapiens OX=9606 GN=IL37 PE=1 SV=1 8.75 2884.8 - 593696 - - - 0.5631 - 1.517 0.379 - 228.5 1 2 0 0.0005 10 0 0 0 1.47E+07 4.84E+06 - - - 3.0034 0.9998 221125_WJC_METTL3_EV_vs_WT_F02.14501.14501.2 0.000161 14-Aug K.EC[160.03]ADLWPR[166.11].L "sp|P62829|RL23_HUMAN,tr|J3KTJ3|J3KTJ3_HUMAN" 2 1055.4734 1.05 14542 14501 2 1055.473195 528.744 60S ribosomal protein L23 OS=Homo sapiens OX=9606 GN=RPL23 PE=1 SV=1 4.37 2885.2 - 9.64E+06 - - - -0.18 - 1.738 0.417 - 417.9 1 2 0 -0.0002 8 0 0 0 4.35E+08 4.13E+08 - - - 3.7879 0.9997 221125_WJC_METTL3_EV_vs_WT_F02.14502.14502.2 0.00621 18-Oct R.IFANTESYLK[136.11].R sp|Q09161|NCBP1_HUMAN 1 1192.6219 1.05 14543 14502 2 1192.620185 597.3182 Nuclear cap-binding protein subunit 1 OS=Homo sapiens OX=9606 GN=NCBP1 PE=1 SV=1 6 2885.3 - 6.50E+06 - - - -1.4715 - 2.035 0.425 - 281.9 1 2 0 -0.0018 10 0 0 0 1.53E+08 1.45E+08 - - - 4.1627 0.9825 221125_WJC_METTL3_EV_vs_WT_F02.14503.14503.2 7.59 12-Jun K.QLLYLEK[136.11].Y "sp|Q93096|TP4A1_HUMAN,sp|Q12974|TP4A2_HUMAN,tr|A0A0D9SGK2|A0A0D9SGK2_HUMAN" 3 913.5364 0.58 14544 14503 2 913.538424 457.7755 Protein tyrosine phosphatase type IVA 1 OS=Homo sapiens OX=9606 GN=PTP4A1 PE=1 SV=2 6 2885.3 - 2.85E+06 - - - 2.1948 - 1.434 0.096 - 138.5 1 2 0 0.002 7 0 0 0 4.43E+07 7.67E+07 - - - 0.8916 0.9992 221125_WJC_METTL3_EV_vs_WT_F02.14504.14504.2 0.0854 16-Oct R.QLLEEELAR.L sp|Q15149|PLEC_HUMAN 1 1099.5873 0.34 14545 14504 2 1099.588529 550.8009 Plectin OS=Homo sapiens OX=9606 GN=PLEC PE=1 SV=3 4.25 2885.4 - 1.27E+06 - - - 1.0822 - 1.923 0.261 - 273.5 1 2 0 0.0012 9 0 0 0 4.31E+07 1.29E+08 - - - 2.8601 0.9998 221125_WJC_METTL3_EV_vs_WT_F02.14505.14505.2 6.25E-05 13/22 R.AEITDAEGLGLK[136.11].L "sp|Q14203|DCTN1_HUMAN,tr|A0A804CDA6|A0A804CDA6_HUMAN,tr|E7EX90|E7EX90_HUMAN,tr|A0A7P0Z4C3|A0A7P0Z4C3_HUMAN" 4 1223.6489 1.91 14546 14505 2 1223.646958 612.8317 Dynactin subunit 1 OS=Homo sapiens OX=9606 GN=DCTN1 PE=1 SV=3 4.14 2885.5 - 1.67E+06 - - - -1.5732 - 2.47 0.475 - 542 1 2 0 -0.0019 12 0 0 0 1.64E+08 8.59E+07 - - - 4.9279 0.9697 221125_WJC_METTL3_EV_vs_WT_F02.14511.14511.2 0.143 14-Jul R.GIAQMLEK.Y "sp|P67870|CSK2B_HUMAN,tr|Q5SRQ3|Q5SRQ3_HUMAN,tr|Q5SRQ6|Q5SRQ6_HUMAN,tr|N0E472|N0E472_HUMAN,tr|A0A7I2YQ78|A0A7I2YQ78_HUMAN,tr|A0A0G2JM12|A0A0G2JM12_HUMAN" 6 888.4739 1.04 14550 14511 2 888.469308 445.2442 Casein kinase II subunit beta OS=Homo sapiens OX=9606 GN=CSNK2B PE=1 SV=1 6 2886.2 - 4.14E+06 - - - -5.156 - 1.578 0.222 - 132 1 2 0 -0.0046 8 0 0 0 1.12E+08 1.07E+08 - - - 2.055 0.9966 221125_WJC_METTL3_EV_vs_WT_F02.14512.14512.2 0.187 14-Sep R.GIAQMLEK[136.11].Y "sp|P67870|CSK2B_HUMAN,tr|Q5SRQ3|Q5SRQ3_HUMAN,tr|Q5SRQ6|Q5SRQ6_HUMAN,tr|N0E472|N0E472_HUMAN,tr|A0A7I2YQ78|A0A7I2YQ78_HUMAN,tr|A0A0G2JM12|A0A0G2JM12_HUMAN" 6 896.4881 1.04 14551 14512 2 896.485865 449.2513 Casein kinase II subunit beta OS=Homo sapiens OX=9606 GN=CSNK2B PE=1 SV=1 6 2886.3 - 4.67E+06 - - - -2.4808 - 1.543 0.259 - 240.8 1 2 0 -0.0022 8 0 0 0 1.12E+08 1.07E+08 - - - 2.2614 0.9994 221125_WJC_METTL3_EV_vs_WT_F02.14515.14515.2 0.562 20-Nov K.ILIIGNSSVGK.T "sp|P20336|RAB3A_HUMAN,sp|P20337|RAB3B_HUMAN,sp|Q96E17|RAB3C_HUMAN,sp|O95716|RAB3D_HUMAN,tr|M0R257|M0R257_HUMAN" 5 1099.6601 0.87 14554 14515 2 1099.660602 550.8373 Ras-related protein Rab-3A OS=Homo sapiens OX=9606 GN=RAB3A PE=1 SV=1 8.75 2886.5 - 1.04E+06 - - - 0.4474 - 1.845 0.294 - 242.9 1 2 0 0.0005 11 0 0 0 1.33E+07 1.52E+07 - - - 2.8692 0.7974 221125_WJC_METTL3_EV_vs_WT_F02.14518.14518.3 0.00229 13/48 S.AVPELATDPELEK[136.11].K "sp|Q86U44|MTA70_HUMAN,tr|B4E349|B4E349_HUMAN,tr|F5H6D8|F5H6D8_HUMAN,tr|H0YFV6|H0YFV6_HUMAN,tr|B4DTN4|B4DTN4_HUMAN" 5 1418.7384 0.6 14555 14518 3 1418.730419 473.9201 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 4 2886.9 - 911746 - - - -5.6437 - 2.133 0.417 - 200.3 1 1 0 -0.008 13 0 0 0 1.38E+07 2.28E+07 - - - 5.2408 0.9941 221125_WJC_METTL3_EV_vs_WT_F02.14520.14520.2 0.35 12-Jun K.ADEWLMK[136.11].N "sp|P35580|MYH10_HUMAN,sp|P35579|MYH9_HUMAN" 2 899.4302 0.8 14557 14520 2 899.42857 450.7224 Myosin-10 OS=Homo sapiens OX=9606 GN=MYH10 PE=1 SV=3 4.37 2887.1 - 5.01E+06 - - - -1.8556 - 1.537 0.144 - 218.8 1 2 0 -0.0017 7 0 0 0 1.11E+08 1.38E+08 - - - 1.466 0.9884 221125_WJC_METTL3_EV_vs_WT_F02.14522.14522.2 0.000158 14/20 V.PELATDPELEK[136.11].K "sp|Q86U44|MTA70_HUMAN,tr|B4E349|B4E349_HUMAN,tr|F5H6D8|F5H6D8_HUMAN,tr|H0YFV6|H0YFV6_HUMAN,tr|B4DTN4|B4DTN4_HUMAN" 5 1248.6329 0.001 14559 14522 2 1248.630277 625.3237 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 4 2887.3 - 567133 - - - -2.0991 - 2.803 0.516 - 589 1 1 0 -0.0026 11 0 0 0 0.00E+00 8.68E+06 - - - 5.6396 0.9997 221125_WJC_METTL3_EV_vs_WT_F02.14525.14525.2 2.62E-05 22-Dec R.ISEYSEAAITIR.G "sp|Q7L014|DDX46_HUMAN,tr|A0A0C4DG89|A0A0C4DG89_HUMAN" 2 1351.6983 2.55 14560 14525 2 1351.694706 676.8564 Probable ATP-dependent RNA helicase DDX46 OS=Homo sapiens OX=9606 GN=DDX46 PE=1 SV=2 4.53 2887.7 - 1.57E+06 - - - -2.6929 - 2.57 0.507 - 652 1 2 0 -0.0036 12 0 0 0 2.88E+07 1.13E+07 - - - 5.2681 0.9999 221125_WJC_METTL3_EV_vs_WT_F02.14530.14530.2 8.92E-06 22-Dec R.ISEYSEAAITIR[166.11].G "sp|Q7L014|DDX46_HUMAN,tr|A0A0C4DG89|A0A0C4DG89_HUMAN" 2 1361.7066 2.53 14565 14530 2 1361.707423 681.8606 Probable ATP-dependent RNA helicase DDX46 OS=Homo sapiens OX=9606 GN=DDX46 PE=1 SV=2 4.53 2888.3 - 491344 - - - 0.5926 - 2.616 0.458 - 698 1 2 0 0.0008 12 0 0 0 2.85E+07 1.13E+07 - - - 4.9538 0.9999 221125_WJC_METTL3_EV_vs_WT_F02.14534.14534.2 1.64E-06 14/22 R.AEITDAEGLGLK.L "sp|Q14203|DCTN1_HUMAN,tr|A0A804CDA6|A0A804CDA6_HUMAN,tr|E7EX90|E7EX90_HUMAN,tr|A0A7P0Z4C3|A0A7P0Z4C3_HUMAN" 4 1215.6347 1.91 14567 14534 2 1215.633013 608.8246 Dynactin subunit 1 OS=Homo sapiens OX=9606 GN=DCTN1 PE=1 SV=3 4.14 2888.8 - 9.11E+06 - - - -1.3738 - 2.486 0.558 - 640.3 1 2 0 -0.0017 12 0 0 0 1.64E+08 8.59E+07 - - - 5.558 0.9968 221125_WJC_METTL3_EV_vs_WT_F02.14536.14536.2 0.266 12-Jul K.QLIAEWK[136.11].K "sp|Q15643|TRIPB_HUMAN,tr|H0YJI2|H0YJI2_HUMAN,tr|H0YJ97|H0YJ97_HUMAN" 3 894.5055 1.11 14569 14536 2 894.504741 448.26 Thyroid receptor-interacting protein 11 OS=Homo sapiens OX=9606 GN=TRIP11 PE=1 SV=3 6 2889 - 5.59E+06 - - - -0.796 - 1.469 0.169 - 183.8 1 2 0 -0.0007 7 0 0 0 1.50E+08 1.35E+08 - - - 1.5076 0.9884 221125_WJC_METTL3_EV_vs_WT_F02.14541.14541.2 0.532 12-Jul K.QLIAEWK.K "sp|Q15643|TRIPB_HUMAN,tr|H0YJI2|H0YJI2_HUMAN,tr|H0YJ97|H0YJ97_HUMAN" 3 886.4913 1.16 14572 14541 2 886.490462 444.2529 Thyroid receptor-interacting protein 11 OS=Homo sapiens OX=9606 GN=TRIP11 PE=1 SV=3 6 2889.6 - 7.95E+06 - - - -0.8923 - 1.273 0.109 - 192.2 1 2 0 -0.0008 7 0 0 0 1.52E+08 1.30E+08 - - - 0.6106 0.9753 221125_WJC_METTL3_EV_vs_WT_F02.14545.14545.2 0.0141 22-Sep R.LLEGEDAHLTQY.K "sp|Q04695|K1C17_HUMAN,tr|A0A3B3IS58|A0A3B3IS58_HUMAN,tr|F5GWP8|F5GWP8_HUMAN" 3 1387.662 - 14576 14545 2 1387.662878 694.8383 "Keratin, type I cytoskeletal 17 OS=Homo sapiens OX=9606 GN=KRT17 PE=1 SV=2" 4.13 2889.9 - 799526 - - - 0.6615 - 1.434 0.455 - 121.9 1 1 0 0.0009 12 0 0 0 - - - - - 3.3498 0.9319 221125_WJC_METTL3_EV_vs_WT_F02.14546.14546.2 0.326 16-Aug K.VLNELTQLK[136.11].Q sp|Q9P0K7|RAI14_HUMAN 1 1064.6321 1.56 14577 14546 2 1064.63575 533.3233 Ankycorbin OS=Homo sapiens OX=9606 GN=RAI14 PE=1 SV=2 5.97 2890 - 2.96E+06 - - - 3.419 - 1.024 0.191 - 113.6 1 2 0 0.0036 9 0 0 0 1.44E+07 9.20E+06 - - - 0.5192 0.996 221125_WJC_METTL3_EV_vs_WT_F02.14547.14547.2 0.0572 22-Nov R.ALSEPLSAAQLR[166.11].R "sp|Q8WUD6|CHPT1_HUMAN,tr|F8W1B3|F8W1B3_HUMAN" 2 1264.7015 1.31 14578 14547 2 1264.700525 633.358 Cholinephosphotransferase 1 OS=Homo sapiens OX=9606 GN=CHPT1 PE=1 SV=1 6.05 2890.2 - 681407 - - - -0.748 - 1.735 0.113 - 349 1 2 0 -0.0009 12 0 0 0 8.96E+06 6.87E+06 - - - 1.3251 0.973 221125_WJC_METTL3_EV_vs_WT_F02.14552.14552.2 0.0595 12-May K.YVIYIER.V "sp|Q9UNX3|RL26L_HUMAN,sp|P61254|RL26_HUMAN,tr|J3QQQ9|J3QQQ9_HUMAN,tr|E5RIT6|E5RIT6_HUMAN,tr|J3QQV1|J3QQV1_HUMAN,tr|J3QRC4|J3QRC4_HUMAN,tr|J3KS10|J3KS10_HUMAN,tr|J3QRI7|J3QRI7_HUMAN" 8 954.5175 1.02 14581 14552 2 954.517542 478.266 60S ribosomal protein L26-like 1 OS=Homo sapiens OX=9606 GN=RPL26L1 PE=1 SV=1 6 2890.8 - 1.44E+06 - - - 0.0775 - 1.275 0.039 - 104.3 2 2 0 0.0001 7 0 0 0 4.64E+07 4.53E+07 - - - -0.0357 0.998 221125_WJC_METTL3_EV_vs_WT_F02.14554.14554.2 0.0423 18-Oct K.ILNLSGNELK.S "sp|Q9UBU9|NXF1_HUMAN,tr|B4E227|B4E227_HUMAN,tr|E9PIN3|E9PIN3_HUMAN" 3 1099.6237 1.06 14583 14554 2 1099.625839 550.8191 Nuclear RNA export factor 1 OS=Homo sapiens OX=9606 GN=NXF1 PE=1 SV=1 6 2891 - 1.65E+06 - - - 1.9234 - 2.022 0.196 - 227.4 1 2 0 0.0021 10 0 0 0 1.38E+08 1.31E+08 - - - 2.4533 0.9976 221125_WJC_METTL3_EV_vs_WT_F02.14555.14555.2 1.04 12-Aug M.PFLDIQK[136.11].R sp|O43920|NDUS5_HUMAN 1 867.4946 1.76 14584 14555 2 867.494028 434.7546 NADH dehydrogenase [ubiquinone] iron-sulfur protein 5 OS=Homo sapiens OX=9606 GN=NDUFS5 PE=1 SV=3 6.26 2891 - 1.41E+06 - - - -0.6063 - 1.671 0.137 - 197.1 1 2 0 -0.0005 7 0 0 0 1.46E+08 8.29E+07 - - - 1.6795 0.9991 221125_WJC_METTL3_EV_vs_WT_F02.14556.14556.2 0.000579 14-Jul K.MVDQLFC[160.03]K.K "sp|P78347|GTF2I_HUMAN,tr|A0A494C0Q7|A0A494C0Q7_HUMAN,tr|A0A494C1K3|A0A494C1K3_HUMAN" 3 1039.4831 1.38 14585 14556 2 1039.48086 520.7488 General transcription factor II-I OS=Homo sapiens OX=9606 GN=GTF2I PE=1 SV=2 5.59 2891.1 - 1.19E+06 - - - -2.1289 - 1.367 0.45 - 156.1 1 2 0 -0.0022 8 0 0 0 3.65E+08 2.64E+08 - - - 3.3068 0.9995 221125_WJC_METTL3_EV_vs_WT_F02.14557.14557.2 0.00225 14-Aug K.TFVFEETR.F "sp|O43435|TBX1_HUMAN,tr|A0A3B3IS18|A0A3B3IS18_HUMAN" 2 1027.4975 1.51 14586 14557 2 1027.49869 514.756 T-box transcription factor TBX1 OS=Homo sapiens OX=9606 GN=TBX1 PE=1 SV=1 4.53 2891.1 - 1.09E+06 - - - 1.1961 - 1.614 0.396 - 231.9 1 2 0 0.0012 8 0 0 0 2.84E+07 1.88E+07 - - - 3.4093 0.9984 221125_WJC_METTL3_EV_vs_WT_F02.14559.14559.2 1.6 14-Aug K.IPSISDLK[136.11].L "sp|Q96RP9|EFGM_HUMAN,tr|F8WAU4|F8WAU4_HUMAN,tr|C9IZ01|C9IZ01_HUMAN" 3 879.5157 0.69 14588 14559 2 879.5152 440.7651 "Elongation factor G, mitochondrial OS=Homo sapiens OX=9606 GN=GFM1 PE=1 SV=2" 5.84 2891.4 - 724330 - - - -0.5503 - 1.668 0.19 - 182.3 1 2 0 -0.0005 8 0 0 0 3.62E+07 5.26E+07 - - - 1.9872 0.9974 221125_WJC_METTL3_EV_vs_WT_F02.14562.14562.2 0.151 14-May K.EC[160.03]ADLWPR.L "sp|P62829|RL23_HUMAN,tr|J3KTJ3|J3KTJ3_HUMAN" 2 1045.4651 1.05 14590 14562 2 1045.46669 523.7398 60S ribosomal protein L23 OS=Homo sapiens OX=9606 GN=RPL23 PE=1 SV=1 4.37 2891.7 - 7.26E+06 - - - 1.5065 - 1.494 0.241 - 174.4 1 2 0 0.0016 8 0 0 0 4.35E+08 4.13E+08 - - - 2.0313 0.9985 221125_WJC_METTL3_EV_vs_WT_F02.14566.14566.2 0.00272 18-Oct R.VAQLEQVYIR.G sp|P62318|SMD3_HUMAN 1 1217.6768 1.53 14593 14566 2 1217.6774 609.8457 Small nuclear ribonucleoprotein Sm D3 OS=Homo sapiens OX=9606 GN=SNRPD3 PE=1 SV=1 5.97 2892 - 1.26E+07 - - - 0.4747 - 2.296 0.102 - 574.8 1 2 0 0.0006 10 0 0 0 3.24E+09 2.12E+09 - - - 2.1142 0.9999 221125_WJC_METTL3_EV_vs_WT_F02.14567.14567.3 0.0499 14/36 K.QLPLVKPYLR.S "sp|Q00610|CLH1_HUMAN,sp|P53675|CLH2_HUMAN,tr|J3KS13|J3KS13_HUMAN,tr|A0A087WXH4|A0A087WXH4_HUMAN,tr|A0A087WVQ6|A0A087WVQ6_HUMAN" 5 1225.7547 0.81 14594 14567 3 1225.75437 409.5922 Clathrin heavy chain 1 OS=Homo sapiens OX=9606 GN=CLTC PE=1 SV=5 9.99 2892.1 - 2.65E+06 - - - -0.2521 - 2.505 0.389 - 382 1 2 0 -0.0003 10 0 0 0 3.74E+07 4.62E+07 - - - 5.5587 0.997 221125_WJC_METTL3_EV_vs_WT_F02.14569.14569.2 8.70E-05 13/18 K.VEAQVYILSK[136.11].E sp|P49411|EFTU_HUMAN 1 1156.6583 1.25 14596 14569 2 1156.652 579.3364 "Elongation factor Tu, mitochondrial OS=Homo sapiens OX=9606 GN=TUFM PE=1 SV=2" 5.97 2892.3 - 977164 - - - -5.4683 - 2.465 0.465 - 601.1 1 2 0 -0.0063 10 0 0 0 9.94E+07 7.92E+07 - - - 4.9918 0.9774 221125_WJC_METTL3_EV_vs_WT_F02.14572.14572.2 0.00712 22-Sep R.ALSEPLSAAQLR.R "sp|Q8WUD6|CHPT1_HUMAN,tr|F8W1B3|F8W1B3_HUMAN" 2 1254.6932 1.29 14599 14572 2 1254.700765 628.3539 Cholinephosphotransferase 1 OS=Homo sapiens OX=9606 GN=CHPT1 PE=1 SV=1 6.05 2892.6 - 500962 - - - 6.0286 - 1.835 0.303 - 258.7 1 2 0 0.0076 12 0 0 0 8.83E+06 6.87E+06 - - - 2.8738 0.9998 221125_WJC_METTL3_EV_vs_WT_F02.14574.14574.2 1.90E-06 20-Nov R.YGEPSEVFINR[166.11].D "sp|Q8WXF1|PSPC1_HUMAN,tr|X6RDA4|X6RDA4_HUMAN" 2 1319.6385 0.22 14601 14574 2 1319.636246 660.8265 Paraspeckle component 1 OS=Homo sapiens OX=9606 GN=PSPC1 PE=1 SV=1 4.53 2892.9 - 299345 - - - -1.7353 - 2.052 0.524 - 465 1 2 0 -0.0023 11 0 0 0 1.00E+06 4.63E+06 - - - 4.8551 0.9836 221125_WJC_METTL3_EV_vs_WT_F02.14578.14578.2 3.04 12-Jun R.FILIQNR.A "sp|P53680|AP2S1_HUMAN,tr|M0R0N4|M0R0N4_HUMAN,tr|X6R390|X6R390_HUMAN,tr|M0QYZ2|M0QYZ2_HUMAN" 4 902.5338 0.76 14603 14578 2 902.532431 452.2742 AP-2 complex subunit sigma OS=Homo sapiens OX=9606 GN=AP2S1 PE=1 SV=2 9.75 2893.4 - 3.11E+06 - - - -1.5024 - 1.22 0.123 - 141.2 1 2 0 -0.0014 7 0 0 0 5.68E+07 7.52E+07 - - - 0.5791 0.999 221125_WJC_METTL3_EV_vs_WT_F02.14579.14579.2 0.075 16-Jul R.SIMAEELVK[136.11].L "sp|P82094|TMF1_HUMAN,tr|A0A2R8Y7M0|A0A2R8Y7M0_HUMAN" 2 1026.5511 1.56 14604 14579 2 1026.551286 514.2828 TATA element modulatory factor OS=Homo sapiens OX=9606 GN=TMF1 PE=1 SV=2 4.53 2893.5 - 2.02E+06 - - - 0.1977 - 1.477 0.303 - 103.2 1 2 0 0.0002 9 0 0 0 1.66E+08 1.06E+08 - - - 2.4072 0.9879 221125_WJC_METTL3_EV_vs_WT_F02.14580.14580.2 0.494 18-Aug K.VEAQVYILSK.E sp|P49411|EFTU_HUMAN 1 1148.6441 1.26 14605 14580 2 1148.648228 575.3293 "Elongation factor Tu, mitochondrial OS=Homo sapiens OX=9606 GN=TUFM PE=1 SV=2" 5.97 2893.5 - 9.83E+06 - - - 3.572 - 1.503 0.233 - 254.9 1 2 0 0.0041 10 0 0 0 9.94E+07 7.91E+07 - - - 1.898 0.9757 221125_WJC_METTL3_EV_vs_WT_F02.14581.14581.2 1.43 16-Jun R.IQAVLALSR[166.11].L "sp|Q9BPX3|CND3_HUMAN,tr|D6RA93|D6RA93_HUMAN" 2 979.6054 1.95 14606 14581 2 979.605356 490.81 Condensin complex subunit 3 OS=Homo sapiens OX=9606 GN=NCAPG PE=1 SV=1 9.75 2893.6 - 3.12E+06 - - - -0.0296 - 1.203 0.09 - 73.3 3 2 0 0 9 0 0 0 2.21E+07 1.14E+07 - - - 0.0273 0.9998 221125_WJC_METTL3_EV_vs_WT_F02.14582.14582.3 0.00254 Nov-36 R.FHALGPIYYR.D sp|Q9UL25|RAB21_HUMAN 1 1235.6451 1.13 14607 14582 3 1235.643428 412.889 Ras-related protein Rab-21 OS=Homo sapiens OX=9606 GN=RAB21 PE=1 SV=3 8.6 2893.6 - 2.19E+06 - - - -1.3758 - 2.319 0.341 - 252.1 1 2 0 -0.0017 10 0 0 0 3.06E+07 2.71E+07 - - - 4.7978 0.9998 221125_WJC_METTL3_EV_vs_WT_F02.14591.14591.2 9.35E-09 16-Oct R.C[160.03]PVEIPPIR.R sp|Q5T749|KPRP_HUMAN 1 1079.5798 175.58 14614 14591 2 1079.579926 540.7972 Keratinocyte proline-rich protein OS=Homo sapiens OX=9606 GN=KPRP PE=1 SV=1 5.99 2894.6 - 3.43E+06 - - - 0.1621 - 2.063 0.454 - 509.4 1 2 0 0.0002 9 0 0 0 7.59E+07 4.32E+05 - - - 4.4892 0.9964 221125_WJC_METTL3_EV_vs_WT_F02.14592.14592.2 0.00718 12-Jul R.AFDIIER[166.11].L "sp|Q8N1F7|NUP93_HUMAN,tr|H3BRD9|H3BRD9_HUMAN,tr|H3BVG0|H3BVG0_HUMAN,tr|H3BV15|H3BV15_HUMAN" 4 872.4631 1.62 14615 14592 2 872.461605 437.2388 Nuclear pore complex protein Nup93 OS=Homo sapiens OX=9606 GN=NUP93 PE=1 SV=2 4.37 2894.7 - 2.84E+06 - - - -1.7571 - 1.281 0.269 - 201.1 1 2 0 -0.0015 7 0 0 0 1.01E+08 6.25E+07 - - - 1.812 0.9952 221125_WJC_METTL3_EV_vs_WT_F02.14593.14593.2 2.24 12-Aug M.PFLDIQK.R sp|O43920|NDUS5_HUMAN 1 859.4804 1.77 14616 14593 2 859.480413 430.7475 NADH dehydrogenase [ubiquinone] iron-sulfur protein 5 OS=Homo sapiens OX=9606 GN=NDUFS5 PE=1 SV=3 6.26 2894.7 - 6.29E+06 - - - 0.0686 - 1.714 0.071 - 175.2 2 2 0 0.0001 7 0 0 0 1.47E+08 8.29E+07 - - - 1.1382 0.9999 221125_WJC_METTL3_EV_vs_WT_F02.14595.14595.2 6.31E-05 14/24 R.LLGLGSASGSVGR[166.11].V sp|Q9BU76|MMTA2_HUMAN 1 1182.6596 1.33 14618 14595 2 1182.659976 592.3371 Multiple myeloma tumor-associated protein 2 OS=Homo sapiens OX=9606 GN=MMTAG2 PE=1 SV=1 9.75 2894.9 - 1.32E+06 - - - 0.3129 - 2.422 0.461 - 549.7 1 2 0 0.0004 13 0 0 0 4.78E+07 3.60E+07 - - - 4.7162 0.975 221125_WJC_METTL3_EV_vs_WT_F02.14598.14598.2 0.0227 24-Oct K.LLAEPAGGLVGER[166.11].T "sp|Q13572|ITPK1_HUMAN,tr|G3V4M9|G3V4M9_HUMAN" 2 1290.7171 1.04 14621 14598 2 1290.70958 646.3658 Inositol-tetrakisphosphate 1-kinase OS=Homo sapiens OX=9606 GN=ITPK1 PE=1 SV=2 4.53 2895.2 - 266105 - - - -5.8425 - 1.881 0.269 - 188.8 1 2 0 -0.0075 13 0 0 0 1.11E+07 1.07E+07 - - - 2.647 0.9995 221125_WJC_METTL3_EV_vs_WT_F02.14602.14602.2 0.00136 16-Jul K.ESYSIYVYK[136.11].V "sp|Q8N257|H2B3B_HUMAN,sp|P33778|H2B1B_HUMAN,sp|Q6DN03|H2B2C_HUMAN,sp|P23527|H2B1O_HUMAN,sp|Q6DRA6|H2B2D_HUMAN,sp|Q16778|H2B2E_HUMAN,sp|P06899|H2B1J_HUMAN" 7 1158.5688 0.99 14623 14602 2 1158.568029 580.2917 Histone H2B type 3-B OS=Homo sapiens OX=9606 GN=H2BU1 PE=1 SV=3 6.1 2895.7 - 4.71E+06 - - - -0.7009 - 1.374 0.438 - 125.4 1 2 0 -0.0008 9 0 0 0 2.91E+08 2.93E+08 - - - 3.195 0.9994 221125_WJC_METTL3_EV_vs_WT_F02.14603.14603.2 0.00206 20-Sep K.QAGVFEPTIVK[136.11].V "sp|P17987|TCPA_HUMAN,tr|F5H282|F5H282_HUMAN,tr|E7EQR6|E7EQR6_HUMAN" 3 1195.6692 0.47 14624 14603 2 1195.667776 598.8419 T-complex protein 1 subunit alpha OS=Homo sapiens OX=9606 GN=TCP1 PE=1 SV=1 6 2895.7 - 1.67E+06 - - - -1.211 - 1.837 0.332 - 212.4 1 2 0 -0.0014 11 0 0 0 9.36E+08 2.00E+09 - - - 3.1378 0.9997 221125_WJC_METTL3_EV_vs_WT_F02.14604.14604.2 0.0372 20-Nov K.VILLGDGGVGK[136.11].S "sp|Q9NP90|RAB9B_HUMAN,sp|P51151|RAB9A_HUMAN,tr|A0A1B0GUI0|A0A1B0GUI0_HUMAN" 3 1034.6215 1.01 14625 14604 2 1034.621404 518.318 Ras-related protein Rab-9B OS=Homo sapiens OX=9606 GN=RAB9B PE=1 SV=1 5.81 2895.8 - 1.13E+06 - - - -0.1372 - 2.01 0.344 - 352.9 1 2 0 -0.0001 11 0 0 0 6.19E+07 6.14E+07 - - - 3.4704 0.9997 221125_WJC_METTL3_EV_vs_WT_F02.14605.14605.2 0.000604 12-Aug K.C[160.03]YYFDYK[136.11].E "sp|P48556|PSMD8_HUMAN,tr|K7EJR3|K7EJR3_HUMAN,tr|R4GMR5|R4GMR5_HUMAN,tr|K7EJC1|K7EJC1_HUMAN,tr|K7ERW6|K7ERW6_HUMAN" 5 1065.4357 0.42 14626 14605 2 1065.435339 533.7251 26S proteasome non-ATPase regulatory subunit 8 OS=Homo sapiens OX=9606 GN=PSMD8 PE=1 SV=2 5.83 2896 - 943321 - - - -0.3567 - 1.389 0.5 - 229.7 1 2 0 -0.0004 7 0 0 0 6.73E+06 1.61E+07 - - - 3.775 0.9878 221125_WJC_METTL3_EV_vs_WT_F02.14606.14606.2 0.0621 16-Aug R.MVGLDIDSR.L sp|Q7L2J0|MEPCE_HUMAN 1 1004.4961 999 14627 14606 2 1004.493664 503.2553 7SK snRNA methylphosphate capping enzyme OS=Homo sapiens OX=9606 GN=MEPCE PE=1 SV=1 4.21 2896.1 - 416990 - - - -2.4062 - 1.398 0.164 - 161 1 2 0 -0.0024 9 0 0 0 1.00E+07 0.00E+00 - - - 1.2208 0.9875 221125_WJC_METTL3_EV_vs_WT_F02.14611.14611.3 0.00221 13/36 R.VAQLEQVYIR[166.11].G sp|P62318|SMD3_HUMAN 1 1227.6851 1.56 14630 14611 3 1227.68475 410.2356 Small nuclear ribonucleoprotein Sm D3 OS=Homo sapiens OX=9606 GN=SNRPD3 PE=1 SV=1 5.97 2896.7 - 2.48E+06 - - - -0.2786 - 2.459 0.045 - 412.2 1 2 0 -0.0003 10 0 0 0 9.34E+07 5.99E+07 - - - 1.6693 0.9906 221125_WJC_METTL3_EV_vs_WT_F02.14612.14612.2 0.229 16-Aug R.GVNLDPLGK[136.11].W "sp|P46087|NOP2_HUMAN,tr|F5GYR3|F5GYR3_HUMAN" 2 919.5218 0.9 14631 14612 2 919.520725 460.7682 Probable 28S rRNA (cytosine(4447)-C(5))-methyltransferase OS=Homo sapiens OX=9606 GN=NOP2 PE=1 SV=2 5.84 2896.7 - 900753 - - - -1.2039 - 1.31 0.139 - 175 1 2 0 -0.0011 9 0 0 0 2.02E+07 2.25E+07 - - - 0.8485 0.7785 221125_WJC_METTL3_EV_vs_WT_F02.14613.14613.2 0.0616 14-Oct V.PQQIEVAR.Q sp|Q96I24|FUBP3_HUMAN 1 939.5138 2.3 14632 14613 2 939.509996 470.7642 Far upstream element-binding protein 3 OS=Homo sapiens OX=9606 GN=FUBP3 PE=1 SV=2 6.43 2896.9 - 333343 - - - -4.0276 - 1.913 0.275 - 391.8 1 1 0 -0.0038 8 0 0 0 7.74E+06 3.37E+06 - - - 3.0273 0.9753 221125_WJC_METTL3_EV_vs_WT_F02.14614.14614.2 1.25 20-May K.YIPVEDLQDPR.C "sp|O15047|SET1A_HUMAN,tr|A0A804HLA6|A0A804HLA6_HUMAN,tr|C9J2Z9|C9J2Z9_HUMAN" 3 1343.6721 2.44 14633 14614 2 1343.67224 672.8433 Histone-lysine N-methyltransferase SETD1A OS=Homo sapiens OX=9606 GN=SETD1A PE=1 SV=3 4.03 2897 - 333342 - - - 0.0811 - 0.939 0.174 - 66.2 2 2 0 0.0001 11 0 0 0 2.01E+07 8.25E+06 - - - 0.0214 0.9966 221125_WJC_METTL3_EV_vs_WT_F02.14616.14616.2 0.0468 18-Jul R.LWC[160.03]ATTYDYK.A "sp|Q9UBV2|SE1L1_HUMAN,tr|G3V3B3|G3V3B3_HUMAN" 2 1319.5856 0.9 14635 14616 2 1319.583881 660.8001 Protein sel-1 homolog 1 OS=Homo sapiens OX=9606 GN=SEL1L PE=1 SV=3 5.83 2897.3 - 206422 - - - -1.3209 - 1.362 0.236 - 77.3 1 2 0 -0.0017 10 0 0 0 5.73E+06 6.39E+06 - - - 1.6459 0.9994 221125_WJC_METTL3_EV_vs_WT_F02.14619.14619.2 0.102 18-Sep K.ILNLSGNELK[136.11].S "sp|Q9UBU9|NXF1_HUMAN,tr|B4E227|B4E227_HUMAN,tr|E9PIN3|E9PIN3_HUMAN" 3 1107.6379 1.06 14636 14619 2 1107.637926 554.8262 Nuclear RNA export factor 1 OS=Homo sapiens OX=9606 GN=NXF1 PE=1 SV=1 6 2897.6 - 6.29E+06 - - - 0.0018 - 1.762 0.293 - 193.5 1 2 0 0 10 0 0 0 1.38E+08 1.31E+08 - - - 2.7862 0.9882 221125_WJC_METTL3_EV_vs_WT_F02.14621.14621.2 0.0827 14-Jul K.AVEGDFFR.V sp|Q9H9S5|FKRP_HUMAN 1 939.445 1.34 14638 14621 2 939.443872 470.7298 Fukutin-related protein OS=Homo sapiens OX=9606 GN=FKRP PE=1 SV=1 4.37 2897.8 - 752479 - - - -1.2337 - 1.208 0.148 - 115.7 1 2 0 -0.0012 8 0 0 0 3.34E+07 2.49E+07 - - - 0.7037 0.9992 221125_WJC_METTL3_EV_vs_WT_F02.14622.14622.2 6.72E-06 24-Sep K.VIDPATATSVDLR[166.11].D sp|P50991|TCPD_HUMAN 1 1366.7332 0.35 14639 14622 2 1366.737364 684.3739 T-complex protein 1 subunit delta OS=Homo sapiens OX=9606 GN=CCT4 PE=1 SV=4 4.21 2898 - 417603 - - - 3.0723 - 1.998 0.479 - 248.2 1 2 0 0.0042 13 0 0 0 9.79E+08 2.84E+09 - - - 4.354 0.9981 221125_WJC_METTL3_EV_vs_WT_F02.14626.14626.2 1.18 16-Aug R.SIMAEELVK.L "sp|P82094|TMF1_HUMAN,tr|A0A2R8Y7M0|A0A2R8Y7M0_HUMAN" 2 1018.5369 1.51 14641 14626 2 1018.537033 510.2757 TATA element modulatory factor OS=Homo sapiens OX=9606 GN=TMF1 PE=1 SV=2 4.53 2898.5 - 1.32E+07 - - - 0.1473 - 1.517 0.214 - 151.5 1 2 0 0.0001 9 0 0 0 1.57E+08 1.04E+08 - - - 1.8272 0.9991 221125_WJC_METTL3_EV_vs_WT_F02.14627.14627.2 0.253 14-Sep K.LLQLVEDR[166.11].G "sp|P17844|DDX5_HUMAN,tr|J3KTA4|J3KTA4_HUMAN,tr|A0A0G2JLI4|A0A0G2JLI4_HUMAN" 3 994.5687 1.56 14642 14627 2 994.56863 498.2916 Probable ATP-dependent RNA helicase DDX5 OS=Homo sapiens OX=9606 GN=DDX5 PE=1 SV=1 4.37 2898.5 - 7.69E+06 - - - -0.0352 - 1.882 0.202 - 363.1 1 2 0 0 8 0 0 0 3.15E+09 2.01E+09 - - - 2.4401 0.9998 221125_WJC_METTL3_EV_vs_WT_F02.14628.14628.2 0.000471 18-Sep R.YVTTILDDAK[136.11].L "sp|Q9HBM6|TAF9B_HUMAN,sp|Q16594|TAF9_HUMAN,tr|D6RIE8|D6RIE8_HUMAN,tr|D6RIV9|D6RIV9_HUMAN,tr|D6RIY1|D6RIY1_HUMAN,tr|D6RGK3|D6RGK3_HUMAN,tr|D6RHW1|D6RHW1_HUMAN" 7 1145.606 4.28 14643 14628 2 1145.606001 573.8103 Transcription initiation factor TFIID subunit 9B OS=Homo sapiens OX=9606 GN=TAF9B PE=1 SV=1 4.21 2898.6 - 4.72E+06 - - - 0.0402 - 1.781 0.476 - 209 1 2 0 0 10 0 0 0 5.53E+08 1.29E+08 - - - 4.1678 0.9997 221125_WJC_METTL3_EV_vs_WT_F02.14629.14629.2 0.000436 16-Sep M.VNFTVDQIR.A sp|P13639|EF2_HUMAN 1 1090.5771 0.51 14644 14629 2 1090.576318 546.2958 Elongation factor 2 OS=Homo sapiens OX=9606 GN=EEF2 PE=1 SV=4 5.81 2898.6 - 1.90E+06 - - - -0.7244 - 1.904 0.351 - 342.7 1 2 0 -0.0008 9 0 0 0 2.86E+08 5.63E+08 - - - 3.4962 0.8389 221125_WJC_METTL3_EV_vs_WT_F02.14630.14630.2 2.28 18-Aug R.LMQQLLESDK[136.11].Y sp|Q92616|GCN1_HUMAN 1 1211.6311 0.4 14645 14630 2 1211.627663 606.8228 eIF-2-alpha kinase activator GCN1 OS=Homo sapiens OX=9606 GN=GCN1 PE=1 SV=6 4.37 2898.8 - 487649 - - - -2.8565 - 1.1 0.043 - 115.8 1 2 0 -0.0035 10 0 0 0 4.76E+06 1.19E+07 - - - -0.3764 0.993 221125_WJC_METTL3_EV_vs_WT_F02.14634.14634.2 0.29 12-Jun K.EELLDIK[136.11].E "sp|Q9NRA8|4ET_HUMAN,sp|Q9NX74|DUS2L_HUMAN,tr|H3BSF3|H3BSF3_HUMAN,tr|B1AKL6|B1AKL6_HUMAN,tr|I3L0K0|I3L0K0_HUMAN,tr|I3L1K5|I3L1K5_HUMAN,tr|H3BM64|H3BM64_HUMAN,tr|H3BMK6|H3BMK6_HUMAN,tr|E7EUN9|E7EUN9_HUMAN,tr|I3L4H0|I3L4H0_HUMAN,tr|B1AKL5|B1AKL5_HUMAN,tr|B1AKL4|B1AKL4_HUMAN,tr|I3L4Y9|I3L4Y9_HUMAN,tr|J3QLD5|J3QLD5_HUMAN,tr|H3BQX4|H3BQX4_HUMAN" 15 866.484 1.02 14647 14634 2 866.482506 434.2493 Eukaryotic translation initiation factor 4E transporter OS=Homo sapiens OX=9606 GN=EIF4ENIF1 PE=1 SV=2 4.14 2899.3 - 3.26E+06 - - - -1.7808 - 1.32 0.187 - 143.7 1 2 0 -0.0015 7 0 0 0 1.72E+08 1.67E+08 - - - 1.3014 0.9996 221125_WJC_METTL3_EV_vs_WT_F02.14635.14635.2 0.0064 14-Aug K.AVYSSWMK[136.11].E sp|Q9BY49|PECR_HUMAN 1 978.4724 0.87 14648 14635 2 978.472149 490.2435 Peroxisomal trans-2-enoyl-CoA reductase OS=Homo sapiens OX=9606 GN=PECR PE=1 SV=2 8.63 2899.4 - 1.01E+06 - - - -0.2964 - 1.705 0.358 - 234.5 1 2 0 -0.0003 8 0 0 0 1.89E+07 2.18E+07 - - - 3.2943 0.9997 221125_WJC_METTL3_EV_vs_WT_F02.14640.14640.2 0.000383 16-Sep K.LLNYAPLEK[136.11].- sp|P62875|RPAB5_HUMAN 1 1067.6106 0.94 14651 14640 2 1067.610551 534.8126 "DNA-directed RNA polymerases I, II, and III subunit RPABC5 OS=Homo sapiens OX=9606 GN=POLR2L PE=1 SV=1" 6 2900 - 1.39E+06 - - - -0.0899 - 1.697 0.422 - 225.7 1 2 0 -0.0001 9 0 0 0 3.36E+07 3.58E+07 - - - 3.6879 0.9935 221125_WJC_METTL3_EV_vs_WT_F02.14642.14642.2 0.317 16-Jun R.YFIDSTNLK[136.11].T "sp|O00488|ZN593_HUMAN,tr|A9J4F5|A9J4F5_HUMAN" 2 1107.5692 0.77 14652 14642 2 1107.572578 554.7919 Zinc finger protein 593 OS=Homo sapiens OX=9606 GN=ZNF593 PE=1 SV=2 5.83 2900.2 - 4.98E+06 - - - 3.0716 - 1.283 0.318 - 75.3 1 2 0 0.0034 9 0 0 0 7.58E+07 9.84E+07 - - - 2.1096 0.9999 221125_WJC_METTL3_EV_vs_WT_F02.14644.14644.2 0.00175 13/22 R.GVLLYGPPGTGK[136.11].T "sp|Q8NB90|AFG2H_HUMAN,sp|P62195|PRS8_HUMAN,sp|P62191|PRS4_HUMAN,tr|J3QQM1|J3QQM1_HUMAN,tr|J3KRP2|J3KRP2_HUMAN,tr|J3QRR3|J3QRR3_HUMAN,tr|J3QSA9|J3QSA9_HUMAN,tr|A0A6Q8PGU6|A0A6Q8PGU6_HUMAN,tr|G3V4X1|G3V4X1_HUMAN,tr|J3QLH6|J3QLH6_HUMAN,tr|J3QRW1|J3QRW1_HUMAN" 11 1165.6587 0.87 14654 14644 2 1165.658418 583.8366 ATPase family protein 2 homolog OS=Homo sapiens OX=9606 GN=SPATA5 PE=1 SV=3 8.59 2900.3 - 5.72E+06 - - - -0.2068 - 2.594 0.401 - 541.5 1 2 0 -0.0002 12 0 0 0 1.29E+08 1.49E+08 - - - 4.5107 0.9956 221125_WJC_METTL3_EV_vs_WT_F02.14647.14647.2 0.00731 24-Dec K.LLAEPAGGLVGER.T "sp|Q13572|ITPK1_HUMAN,tr|G3V4M9|G3V4M9_HUMAN" 2 1280.7089 0.96 14657 14647 2 1280.704474 641.3617 Inositol-tetrakisphosphate 1-kinase OS=Homo sapiens OX=9606 GN=ITPK1 PE=1 SV=2 4.53 2900.6 - 509107 - - - -3.4176 - 1.961 0.257 - 231.3 1 2 0 -0.0044 13 0 0 0 1.01E+07 1.05E+07 - - - 2.6663 0.9992 221125_WJC_METTL3_EV_vs_WT_F02.14650.14650.2 0.0119 16-Oct K.TVEPLEYYR[166.11].R sp|Q96B26|EXOS8_HUMAN 1 1178.5847 0.75 14659 14650 2 1178.584371 590.2996 Exosome complex component RRP43 OS=Homo sapiens OX=9606 GN=EXOSC8 PE=1 SV=1 4.53 2901 - 3.45E+06 - - - -0.2876 - 1.894 0.22 - 279.2 1 2 0 -0.0003 9 0 0 0 7.45E+07 9.99E+07 - - - 2.5136 0.9999 221125_WJC_METTL3_EV_vs_WT_F02.14652.14652.2 3.03E-05 16-Sep K.VDELEAALR.M sp|Q8N1N4|K2C78_HUMAN 1 1014.5346 2.83 14660 14652 2 1014.535119 508.2746 "Keratin, type II cytoskeletal 78 OS=Homo sapiens OX=9606 GN=KRT78 PE=1 SV=2" 4.14 2901.2 - 9.59E+06 - - - 0.5362 - 2.246 0.45 - 334.2 1 2 0 0.0005 9 0 0 0 2.43E+08 8.59E+07 - - - 4.7054 0.9969 221125_WJC_METTL3_EV_vs_WT_F02.14653.14653.2 0.178 12-Aug K.EELLDIK.E "sp|Q9NRA8|4ET_HUMAN,sp|Q9NX74|DUS2L_HUMAN,tr|H3BSF3|H3BSF3_HUMAN,tr|B1AKL6|B1AKL6_HUMAN,tr|I3L0K0|I3L0K0_HUMAN,tr|I3L1K5|I3L1K5_HUMAN,tr|H3BM64|H3BM64_HUMAN,tr|H3BMK6|H3BMK6_HUMAN,tr|E7EUN9|E7EUN9_HUMAN,tr|I3L4H0|I3L4H0_HUMAN,tr|B1AKL5|B1AKL5_HUMAN,tr|B1AKL4|B1AKL4_HUMAN,tr|I3L4Y9|I3L4Y9_HUMAN,tr|J3QLD5|J3QLD5_HUMAN,tr|H3BQX4|H3BQX4_HUMAN" 15 858.4698 0.99 14661 14653 2 858.46967 430.2422 Eukaryotic translation initiation factor 4E transporter OS=Homo sapiens OX=9606 GN=EIF4ENIF1 PE=1 SV=2 4.14 2901.2 - 5.06E+06 - - - -0.2085 - 1.447 0.169 - 265.5 1 2 0 -0.0002 7 0 0 0 1.66E+08 1.67E+08 - - - 1.4599 0.9956 221125_WJC_METTL3_EV_vs_WT_F02.14655.14655.2 0.115 12-Jun K.VDWLTEK[136.11].M "sp|Q14240|IF4A2_HUMAN,sp|P38919|IF4A3_HUMAN,sp|P60842|IF4A1_HUMAN,tr|J3QL52|J3QL52_HUMAN,tr|J3KT12|J3KT12_HUMAN,tr|J3QS69|J3QS69_HUMAN,tr|I3L3H2|I3L3H2_HUMAN,tr|J3QL43|J3QL43_HUMAN,tr|J3KTN0|J3KTN0_HUMAN,tr|E7EQG2|E7EQG2_HUMAN,tr|J3KSZ0|J3KSZ0_HUMAN" 11 897.4687 1.45 14663 14655 2 897.466826 449.7416 Eukaryotic initiation factor 4A-II OS=Homo sapiens OX=9606 GN=EIF4A2 PE=1 SV=2 4.37 2901.4 - 1.71E+06 - - - -2.1249 - 1.39 0.238 - 111.7 1 2 0 -0.0019 7 0 0 0 1.35E+08 9.29E+07 - - - 1.8417 0.9996 221125_WJC_METTL3_EV_vs_WT_F02.14657.14657.2 0.00612 22-Oct K.LFVVPADEAQAR.L sp|Q8IV08|PLD3_HUMAN 1 1314.6932 3.64 14665 14657 2 1314.690895 658.3539 5'-3' exonuclease PLD3 OS=Homo sapiens OX=9606 GN=PLD3 PE=1 SV=1 4.37 2901.6 - 668065 - - - -1.754 - 2.071 0.425 - 325.4 1 2 0 -0.0023 12 0 0 0 2.36E+07 6.48E+06 - - - 4.0949 0.9993 221125_WJC_METTL3_EV_vs_WT_F02.14660.14660.2 0.00551 12-Jul K.VDWLTEK.M "sp|Q14240|IF4A2_HUMAN,sp|P38919|IF4A3_HUMAN,sp|P60842|IF4A1_HUMAN,tr|J3QL52|J3QL52_HUMAN,tr|J3KT12|J3KT12_HUMAN,tr|J3QS69|J3QS69_HUMAN,tr|I3L3H2|I3L3H2_HUMAN,tr|J3QL43|J3QL43_HUMAN,tr|J3KTN0|J3KTN0_HUMAN,tr|E7EQG2|E7EQG2_HUMAN,tr|J3KSZ0|J3KSZ0_HUMAN" 11 889.4545 1.45 14666 14660 2 889.454031 445.7345 Eukaryotic initiation factor 4A-II OS=Homo sapiens OX=9606 GN=EIF4A2 PE=1 SV=2 4.37 2902 - 3.67E+06 - - - -0.5644 - 1.596 0.296 - 174.8 1 2 0 -0.0005 7 0 0 0 1.35E+08 9.31E+07 - - - 2.7084 0.9992 221125_WJC_METTL3_EV_vs_WT_F02.14661.14661.2 0.0232 20-Aug K.VILLGDGGVGK.S "sp|Q9NP90|RAB9B_HUMAN,sp|P51151|RAB9A_HUMAN,tr|A0A1B0GUI0|A0A1B0GUI0_HUMAN" 3 1026.6073 0.98 14667 14661 2 1026.607567 514.3109 Ras-related protein Rab-9B OS=Homo sapiens OX=9606 GN=RAB9B PE=1 SV=1 5.81 2902 - 2.37E+06 - - - 0.2153 - 1.637 0.293 - 122.7 1 2 0 0.0002 11 0 0 0 6.33E+07 6.45E+07 - - - 2.5383 0.9992 221125_WJC_METTL3_EV_vs_WT_F02.14662.14662.2 0.00491 18-Aug K.SFLSQGQVLK[136.11].L "sp|P48047|ATPO_HUMAN,tr|H7C068|H7C068_HUMAN" 2 1113.6274 0.85 14668 14662 2 1113.62857 557.821 "ATP synthase subunit O, mitochondrial OS=Homo sapiens OX=9606 GN=ATP5PO PE=1 SV=1" 8.47 2902.1 - 5.12E+06 - - - 1.0874 - 1.658 0.32 - 165.3 1 2 0 0.0012 10 0 0 0 2.63E+08 3.08E+08 - - - 2.8155 0.9941 221125_WJC_METTL3_EV_vs_WT_F02.14665.14665.3 0.47 Oct-48 K.VIDPATATSVDLR[166.11].D sp|P50991|TCPD_HUMAN 1 1366.7332 0.36 14671 14665 3 1366.731309 456.585 T-complex protein 1 subunit delta OS=Homo sapiens OX=9606 GN=CCT4 PE=1 SV=4 4.21 2902.4 - 371369 - - - -1.358 - 1.749 0.196 - 107.5 1 2 0 -0.0019 13 0 0 0 1.44E+08 4.04E+08 - - - 2.2404 0.9978 221125_WJC_METTL3_EV_vs_WT_F02.14669.14669.2 0.215 14-Aug R.TLTTLLEK.V sp|Q8IYI6|EXOC8_HUMAN 1 917.5433 1.39 14673 14669 2 917.541891 459.779 Exocyst complex component 8 OS=Homo sapiens OX=9606 GN=EXOC8 PE=1 SV=2 5.66 2902.9 - 1.59E+06 - - - -1.5879 - 1.421 0.272 - 174 1 2 0 -0.0015 8 0 0 0 1.61E+08 1.16E+08 - - - 2.1092 0.9998 221125_WJC_METTL3_EV_vs_WT_F02.14670.14670.2 0.000119 18-Nov K.IETIEVMEDR.Q "sp|P51991|ROA3_HUMAN,tr|A0A7I2V5D8|A0A7I2V5D8_HUMAN,tr|A0A7I2V2R3|A0A7I2V2R3_HUMAN,tr|A0A7I2V4J6|A0A7I2V4J6_HUMAN,tr|A0A7I2V4G0|A0A7I2V4G0_HUMAN,tr|A0A7I2V402|A0A7I2V402_HUMAN" 6 1233.5911 1.29 14674 14670 2 1233.588631 617.8028 Heterogeneous nuclear ribonucleoprotein A3 OS=Homo sapiens OX=9606 GN=HNRNPA3 PE=1 SV=2 4 2903 - 1.66E+06 - - - -2.0039 - 2.469 0.52 - 460.3 1 2 0 -0.0025 10 0 0 0 7.97E+08 6.16E+08 - - - 5.4038 0.9983 221125_WJC_METTL3_EV_vs_WT_F02.14671.14671.2 0.0184 14-Jun K.AVEGDFFR[166.11].V sp|Q9H9S5|FKRP_HUMAN 1 949.4533 1.4 14675 14671 2 949.453047 475.7339 Fukutin-related protein OS=Homo sapiens OX=9606 GN=FKRP PE=1 SV=1 4.37 2903 - 1.08E+06 - - - -0.2675 - 1.244 0.299 - 128.9 1 2 0 -0.0003 8 0 0 0 3.32E+07 2.36E+07 - - - 1.9078 0.9998 221125_WJC_METTL3_EV_vs_WT_F02.14672.14672.2 0.00142 14/22 K.MIEEAGAIISTR.H "sp|O00154|BACH_HUMAN,tr|K7EKP8|K7EKP8_HUMAN" 2 1289.6649 0.62 14676 14672 2 1289.666369 645.8397 Cytosolic acyl coenzyme A thioester hydrolase OS=Homo sapiens OX=9606 GN=ACOT7 PE=1 SV=3 4.53 2903.2 - 616389 - - - 1.1104 - 2.381 0.483 - 556.2 1 2 0 0.0014 12 0 0 0 1.05E+07 1.70E+07 - - - 4.8906 0.9822 221125_WJC_METTL3_EV_vs_WT_F02.14673.14673.2 4.40E-05 20-Oct R.NLAMEATYINH.N sp|O15371|EIF3D_HUMAN 1 1275.5918 - 14677 14673 2 1275.589366 638.8032 Eukaryotic translation initiation factor 3 subunit D OS=Homo sapiens OX=9606 GN=EIF3D PE=1 SV=1 5.24 2903.3 - 603430 - - - -1.8862 - 1.817 0.519 - 240.7 1 1 0 -0.0024 11 0 0 0 - - - - - 4.4891 0.9993 221125_WJC_METTL3_EV_vs_WT_F02.14674.14674.2 1.17E-05 22-Dec K.MIEEAGAIISTR[166.11].H "sp|O00154|BACH_HUMAN,tr|K7EKP8|K7EKP8_HUMAN" 2 1299.6732 0.62 14678 14674 2 1299.677467 650.8439 Cytosolic acyl coenzyme A thioester hydrolase OS=Homo sapiens OX=9606 GN=ACOT7 PE=1 SV=3 4.53 2903.4 - 531848 - - - 3.2777 - 2.231 0.508 - 438.2 1 2 0 0.0043 12 0 0 0 1.05E+07 1.70E+07 - - - 4.9031 0.9992 221125_WJC_METTL3_EV_vs_WT_F02.14675.14675.2 2.32E-06 22-Dec K.LFVVPADEAQAR[166.11].L sp|Q8IV08|PLD3_HUMAN 1 1324.7015 3.64 14679 14675 2 1324.706394 663.358 5'-3' exonuclease PLD3 OS=Homo sapiens OX=9606 GN=PLD3 PE=1 SV=1 4.37 2903.6 - 213318 - - - 3.7163 - 2.353 0.521 - 437.5 1 2 0 0.0049 12 0 0 0 2.36E+07 6.48E+06 - - - 5.139 0.8702 221125_WJC_METTL3_EV_vs_WT_F02.14678.14678.2 0.672 14-Jun K.TIIFVETK.R "sp|Q92841|DDX17_HUMAN,tr|A0A5H1ZRQ2|A0A5H1ZRQ2_HUMAN,tr|A0A1X7SBZ2|A0A1X7SBZ2_HUMAN" 3 949.5484 0.55 14680 14678 2 949.544365 475.7815 Probable ATP-dependent RNA helicase DDX17 OS=Homo sapiens OX=9606 GN=DDX17 PE=1 SV=2 5.66 2903.9 - 1.22E+06 - - - -4.2852 - 1.096 0.172 - 98 2 2 0 -0.0041 8 0 0 0 2.92E+08 5.30E+08 - - - 0.4521 0.9995 221125_WJC_METTL3_EV_vs_WT_F02.14679.14679.2 6.51E-05 16-Sep K.FGVYDIDNK.T "sp|O75131|CPNE3_HUMAN,tr|E5RHZ0|E5RHZ0_HUMAN,tr|A0A087WXR6|A0A087WXR6_HUMAN,tr|A0A087WYQ3|A0A087WYQ3_HUMAN,tr|A0A087WUS8|A0A087WUS8_HUMAN" 5 1069.508 0.57 14681 14679 2 1069.505788 535.7613 Copine-3 OS=Homo sapiens OX=9606 GN=CPNE3 PE=1 SV=1 4.21 2904 - 824339 - - - -2.0926 - 1.703 0.475 - 210.1 1 2 0 -0.0022 9 0 0 0 2.15E+07 3.80E+07 - - - 4.0889 0.9791 221125_WJC_METTL3_EV_vs_WT_F02.14681.14681.2 0.00771 16-Aug K.QPPIDNIIR.A "sp|P52292|IMA1_HUMAN,tr|J3QLL0|J3QLL0_HUMAN,tr|J3KS65|J3KS65_HUMAN,tr|A0A7I2V3Z3|A0A7I2V3Z3_HUMAN,tr|A0A7I2YQE1|A0A7I2YQE1_HUMAN,tr|A0A7I2V487|A0A7I2V487_HUMAN,tr|A0A7I2V351|A0A7I2V351_HUMAN" 7 1064.5978 0.97 14683 14681 2 1064.603322 533.3062 Importin subunit alpha-1 OS=Homo sapiens OX=9606 GN=KPNA2 PE=1 SV=1 5.84 2904.3 - 754762 - - - 5.1456 - 1.421 0.317 - 247.6 1 2 0 0.0055 9 0 0 0 4.21E+07 4.34E+07 - - - 2.3971 0.9948 221125_WJC_METTL3_EV_vs_WT_F02.14682.14682.2 2.12 12-Jul K.DIAAYIK.K sp|Q96FJ2|DYL2_HUMAN 1 792.4382 1.53 14684 14682 2 792.437568 397.2264 "Dynein light chain 2, cytoplasmic OS=Homo sapiens OX=9606 GN=DYNLL2 PE=1 SV=1" 5.83 2904.4 - 526412 - - - -0.7408 - 1.428 0.149 - 136.7 2 2 0 -0.0006 7 0 0 0 1.04E+08 6.83E+07 - - - 1.1357 0.9996 221125_WJC_METTL3_EV_vs_WT_F02.14683.14683.2 2.80E-06 24-Oct R.TTPSYVAFTDTER[166.11].L "sp|P48741|HSP77_HUMAN,sp|P54652|HSP72_HUMAN,sp|P0DMV8|HS71A_HUMAN,sp|P34931|HS71L_HUMAN,sp|P11142|HSP7C_HUMAN,sp|P0DMV9|HS71B_HUMAN,sp|P17066|HSP76_HUMAN,tr|E9PQQ4|E9PQQ4_HUMAN,tr|E9PNE6|E9PNE6_HUMAN,tr|E9PKE3|E9PKE3_HUMAN,tr|E9PLF4|E9PLF4_HUMAN,tr|Q53FA3|Q53FA3_HUMAN,tr|E9PI65|E9PI65_HUMAN,tr|E9PK54|E9PK54_HUMAN,tr|E9PN25|E9PN25_HUMAN,tr|E9PPY6|E9PPY6_HUMAN,tr|E9PQK7|E9PQK7_HUMAN,tr|A0A0G2JIW1|A0A0G2JIW1_HUMAN" 18 1496.7023 0.06 14685 14683 2 1496.706302 749.3584 Putative heat shock 70 kDa protein 7 OS=Homo sapiens OX=9606 GN=HSPA7 PE=5 SV=2 4.37 2904.6 - 288103 - - - 2.7013 - 2.175 0.569 - 293.2 1 2 0 0.004 13 0 0 0 1.07E+06 1.77E+07 - - - 5.2366 0.9998 221125_WJC_METTL3_EV_vs_WT_F02.14685.14685.2 6.68E-05 20-Oct K.QAGVFEPTIVK.V "sp|P17987|TCPA_HUMAN,tr|F5H282|F5H282_HUMAN,tr|E7EQR6|E7EQR6_HUMAN" 3 1187.655 0.47 14686 14685 2 1187.654864 594.8348 T-complex protein 1 subunit alpha OS=Homo sapiens OX=9606 GN=TCP1 PE=1 SV=1 6 2904.8 - 4.18E+07 - - - -0.1347 - 2.111 0.431 - 402.5 1 2 0 -0.0002 11 0 0 0 9.36E+08 2.00E+09 - - - 4.2456 0.9995 221125_WJC_METTL3_EV_vs_WT_F02.14686.14686.2 0.00165 16-Jul K.ESYSIYVYK.V "sp|Q8N257|H2B3B_HUMAN,sp|P33778|H2B1B_HUMAN,sp|Q6DN03|H2B2C_HUMAN,sp|P23527|H2B1O_HUMAN,sp|Q6DRA6|H2B2D_HUMAN,sp|Q16778|H2B2E_HUMAN,sp|P06899|H2B1J_HUMAN" 7 1150.5546 1 14687 14686 2 1150.553748 576.2846 Histone H2B type 3-B OS=Homo sapiens OX=9606 GN=H2BU1 PE=1 SV=3 6.1 2904.8 - 5.60E+06 - - - -0.7761 - 1.513 0.393 - 147.7 1 2 0 -0.0009 9 0 0 0 2.92E+08 2.93E+08 - - - 3.1414 0.9992 221125_WJC_METTL3_EV_vs_WT_F02.14687.14687.2 0.00146 18-Sep K.SFLSQGQVLK.L "sp|P48047|ATPO_HUMAN,tr|H7C068|H7C068_HUMAN" 2 1105.6132 0.85 14688 14687 2 1105.614121 553.8139 "ATP synthase subunit O, mitochondrial OS=Homo sapiens OX=9606 GN=ATP5PO PE=1 SV=1" 8.47 2904.8 - 1.21E+07 - - - 0.8701 - 1.563 0.343 - 216.4 1 2 0 0.001 10 0 0 0 2.63E+08 3.08E+08 - - - 2.8207 0.9927 221125_WJC_METTL3_EV_vs_WT_F02.14688.14688.2 2.84 12-Jul K.DIAAYIK[136.11].K sp|Q96FJ2|DYL2_HUMAN 1 800.4524 1.52 14689 14688 2 800.451762 401.2335 "Dynein light chain 2, cytoplasmic OS=Homo sapiens OX=9606 GN=DYNLL2 PE=1 SV=1" 5.83 2905 - 833403 - - - -0.7408 - 1.303 0.137 - 153.1 1 2 0 -0.0006 7 0 0 0 1.04E+08 6.87E+07 - - - 0.8913 0.9998 221125_WJC_METTL3_EV_vs_WT_F02.14693.14693.2 0.00863 22-Dec R.LLSASPVDAAIR.V "sp|Q9NRG9|AAAS_HUMAN,tr|H3BU82|H3BU82_HUMAN,tr|F8VZ44|F8VZ44_HUMAN" 3 1211.6874 1.21 14692 14693 2 1211.686198 606.851 Aladin OS=Homo sapiens OX=9606 GN=AAAS PE=1 SV=1 5.84 2905.6 - 4.28E+06 - - - -0.9813 - 2.436 0.432 - 465.5 1 2 0 -0.0012 12 0 0 0 8.51E+07 7.04E+07 - - - 4.5741 0.9968 221125_WJC_METTL3_EV_vs_WT_F02.14695.14695.2 0.0132 14-Aug K.GAWSNVLR.G "sp|P12235|ADT1_HUMAN,sp|P05141|ADT2_HUMAN,sp|P12236|ADT3_HUMAN" 3 901.477 0.82 14694 14695 2 901.48024 451.7458 ADP\ATP translocase 1 OS=Homo sapiens OX=9606 GN=SLC25A4 PE=1 SV=4 9.75 2905.7 - 2.83E+06 - - - 3.5941 - 1.52 0.384 - 245.5 1 2 0 0.0032 8 0 0 0 3.36E+08 4.11E+08 - - - 3.139 0.9998 221125_WJC_METTL3_EV_vs_WT_F02.14699.14699.2 4.89E-05 24-Nov K.VIDPATATSVDLR.D sp|P50991|TCPD_HUMAN 1 1356.7249 0.35 14697 14699 2 1356.726549 679.3697 T-complex protein 1 subunit delta OS=Homo sapiens OX=9606 GN=CCT4 PE=1 SV=4 4.21 2906 - 3.21E+06 - - - 1.2191 - 2.291 0.54 - 449 1 2 0 0.0017 13 0 0 0 9.79E+08 2.84E+09 - - - 5.1565 0.9998 221125_WJC_METTL3_EV_vs_WT_F02.14701.14701.2 1.67E-05 18-Sep R.AAEAAINILK.A "sp|O75569|PRKRA_HUMAN,tr|A0A7I2V5C2|A0A7I2V5C2_HUMAN,tr|A0A7I2V5H3|A0A7I2V5H3_HUMAN,tr|A0A7I2V2P4|A0A7I2V2P4_HUMAN,tr|F8WEG8|F8WEG8_HUMAN,tr|G5E9Q4|G5E9Q4_HUMAN,tr|A0A7I2YQ87|A0A7I2YQ87_HUMAN,tr|A0A7I2V315|A0A7I2V315_HUMAN,tr|A0A7I2V593|A0A7I2V593_HUMAN,tr|C9JMM3|C9JMM3_HUMAN,tr|A0A7I2V3L6|A0A7I2V3L6_HUMAN" 11 1012.5917 1.59 14698 14701 2 1012.592275 507.3031 Interferon-inducible double-stranded RNA-dependent protein kinase activator A OS=Homo sapiens OX=9606 GN=PRKRA PE=1 SV=1 6.05 2906.2 - 2.12E+06 - - - 0.5718 - 1.993 0.482 - 330.4 1 2 0 0.0006 10 0 0 0 7.77E+07 4.89E+07 - - - 4.5259 0.9487 221125_WJC_METTL3_EV_vs_WT_F02.14702.14702.2 0.0587 12-Jul E.SVADYFK[136.11].Q "sp|P35637|FUS_HUMAN,tr|H3BPE7|H3BPE7_HUMAN" 2 836.416 1 14699 14702 2 836.415319 419.2153 RNA-binding protein FUS OS=Homo sapiens OX=9606 GN=FUS PE=1 SV=1 5.55 2906.3 - 1.88E+06 - - - -0.7783 - 1.176 0.406 - 155.9 1 1 0 -0.0007 7 0 0 0 4.67E+07 4.66E+07 - - - 2.5532 0.8755 221125_WJC_METTL3_EV_vs_WT_F02.14703.14703.2 4.29 14-Jul R.LSLENLEK.L "sp|Q9Y2H2|SAC2_HUMAN,tr|A0A0J9YY79|A0A0J9YY79_HUMAN,tr|A0A3B3ISI3|A0A3B3ISI3_HUMAN,tr|A0A3B3IRJ9|A0A3B3IRJ9_HUMAN,tr|A0A1B0GUS5|A0A1B0GUS5_HUMAN,tr|A0A3B3ITL0|A0A3B3ITL0_HUMAN,tr|A0A3B3ITR9|A0A3B3ITR9_HUMAN" 7 944.5179 2.71 14700 14703 2 944.513536 473.2662 Phosphatidylinositide phosphatase SAC2 OS=Homo sapiens OX=9606 GN=INPP5F PE=1 SV=3 4.53 2906.5 - 531759 - - - -4.5801 - 1.385 0.082 - 75 1 2 0 -0.0043 8 0 0 0 2.60E+07 9.58E+06 - - - 0.6276 0.9997 221125_WJC_METTL3_EV_vs_WT_F02.14705.14705.2 0.000995 26-Aug K.VMEGTVAAQDEFYR.S sp|P41240|CSK_HUMAN 1 1614.7348 0.56 14702 14705 2 1614.734281 808.3747 Tyrosine-protein kinase CSK OS=Homo sapiens OX=9606 GN=CSK PE=1 SV=1 4.14 2906.7 - 0 - - - -0.3264 - 1.643 0.465 - 116.3 1 2 0 -0.0005 14 0 0 0 1.61E+06 2.86E+06 - - - 3.7213 0.9982 221125_WJC_METTL3_EV_vs_WT_F02.14708.14708.2 0.0116 18-Aug K.QPGITFIAAK.F "sp|P07339|CATD_HUMAN,tr|A0A1B0GW44|A0A1B0GW44_HUMAN,tr|A0A1B0GVD5|A0A1B0GVD5_HUMAN,tr|A0A1B0GV23|A0A1B0GV23_HUMAN,tr|C9JH19|C9JH19_HUMAN,tr|A0A1B0GWE8|A0A1B0GWE8_HUMAN,tr|A0A1B0GU03|A0A1B0GU03_HUMAN,tr|A0A1B0GVP3|A0A1B0GVP3_HUMAN,tr|F8WD96|F8WD96_HUMAN,tr|A0A1B0GU92|A0A1B0GU92_HUMAN,tr|F8W787|F8W787_HUMAN" 11 1044.5968 7.37 14703 14708 2 1044.595709 523.3057 Cathepsin D OS=Homo sapiens OX=9606 GN=CTSD PE=1 SV=1 8.75 2907.1 - 3.11E+06 - - - -1.0262 - 1.528 0.247 - 222.5 1 2 0 -0.0011 10 0 0 0 9.95E+07 1.35E+07 - - - 2.0484 0.9996 221125_WJC_METTL3_EV_vs_WT_F02.14709.14709.2 0.00165 18-Sep R.AAEAAINILK[136.11].A "sp|O75569|PRKRA_HUMAN,tr|A0A7I2V5C2|A0A7I2V5C2_HUMAN,tr|A0A7I2V5H3|A0A7I2V5H3_HUMAN,tr|A0A7I2V2P4|A0A7I2V2P4_HUMAN,tr|F8WEG8|F8WEG8_HUMAN,tr|G5E9Q4|G5E9Q4_HUMAN,tr|A0A7I2YQ87|A0A7I2YQ87_HUMAN,tr|A0A7I2V315|A0A7I2V315_HUMAN,tr|A0A7I2V593|A0A7I2V593_HUMAN,tr|C9JMM3|C9JMM3_HUMAN,tr|A0A7I2V3L6|A0A7I2V3L6_HUMAN" 11 1020.6059 1.6 14704 14709 2 1020.607201 511.3102 Interferon-inducible double-stranded RNA-dependent protein kinase activator A OS=Homo sapiens OX=9606 GN=PRKRA PE=1 SV=1 6.05 2907.2 - 1.24E+06 - - - 1.2787 - 2.028 0.355 - 306.5 1 2 0 0.0013 10 0 0 0 7.77E+07 4.86E+07 - - - 3.6362 0.9864 221125_WJC_METTL3_EV_vs_WT_F02.14714.14714.2 4.57E-05 18-Sep F.LMSALESMC[160.03]K.E "sp|P78347|GTF2I_HUMAN,tr|C9J6M0|C9J6M0_HUMAN,tr|A0A494C1K3|A0A494C1K3_HUMAN" 3 1168.529 1.52 14707 14714 2 1168.527397 585.2718 General transcription factor II-I OS=Homo sapiens OX=9606 GN=GTF2I PE=1 SV=2 5.99 2907.6 - 2.00E+06 - - - -1.4035 - 1.792 0.51 - 250.4 1 1 0 -0.0016 10 0 0 0 4.59E+07 3.03E+07 - - - 4.4356 0.9966 221125_WJC_METTL3_EV_vs_WT_F02.14715.14715.2 0.0229 16-Sep R.VIDVGSEWR[166.11].T "sp|Q00403|TF2B_HUMAN,tr|B1APE1|B1APE1_HUMAN,tr|B1APE2|B1APE2_HUMAN" 3 1069.5432 0.001 14708 14715 2 1069.547209 535.7789 Transcription initiation factor IIB OS=Homo sapiens OX=9606 GN=GTF2B PE=1 SV=1 4.37 2907.8 - 883683 - - - 3.768 - 1.785 0.335 - 211.7 1 2 0 0.004 9 0 0 0 0.00E+00 1.71E+07 - - - 3.1903 0.9995 221125_WJC_METTL3_EV_vs_WT_F02.14720.14720.2 0.00875 14-Jul K.TIIFVETK[136.11].R "sp|Q92841|DDX17_HUMAN,tr|A0A5H1ZRQ2|A0A5H1ZRQ2_HUMAN,tr|A0A1X7SBZ2|A0A1X7SBZ2_HUMAN" 3 957.5626 0.54 14711 14720 2 957.562198 479.7886 Probable ATP-dependent RNA helicase DDX17 OS=Homo sapiens OX=9606 GN=DDX17 PE=1 SV=2 5.66 2908.4 - 1.06E+07 - - - -0.4553 - 1.401 0.417 - 144 1 2 0 -0.0004 8 0 0 0 2.96E+08 5.44E+08 - - - 3.1378 0.9999 221125_WJC_METTL3_EV_vs_WT_F02.14724.14724.2 2.60E-05 22-Nov R.LLSASPVDAAIR[166.11].V "sp|Q9NRG9|AAAS_HUMAN,tr|H3BU82|H3BU82_HUMAN,tr|F8VZ44|F8VZ44_HUMAN" 3 1221.6957 1.21 14715 14724 2 1221.696696 611.8551 Aladin OS=Homo sapiens OX=9606 GN=AAAS PE=1 SV=1 5.84 2908.6 - 2.20E+06 - - - 0.8505 - 2.259 0.514 - 359.4 1 2 0 0.001 12 0 0 0 8.51E+07 7.03E+07 - - - 4.9813 0.9789 221125_WJC_METTL3_EV_vs_WT_F02.14726.14726.2 0.588 14-Sep K.IIQEFLSK.V sp|P43246|MSH2_HUMAN 1 976.5593 1.29 14717 14726 2 976.560945 489.2869 DNA mismatch repair protein Msh2 OS=Homo sapiens OX=9606 GN=MSH2 PE=1 SV=1 6 2908.8 - 956417 - - - 1.6507 - 1.616 0.006 - 156.3 1 2 0 0.0016 8 0 0 0 4.02E+07 3.11E+07 - - - 0.5323 0.997 221125_WJC_METTL3_EV_vs_WT_F02.14729.14729.2 0.47 14-Jul R.ELAFQISK[136.11].E "sp|Q13838|DX39B_HUMAN,sp|O00148|DX39A_HUMAN,tr|K7EPJ3|K7EPJ3_HUMAN,tr|F6TRA5|F6TRA5_HUMAN,tr|F6WLT2|F6WLT2_HUMAN,tr|Q5STU3|Q5STU3_HUMAN,tr|A0A140T973|A0A140T973_HUMAN,tr|A0A140T9K2|A0A140T9K2_HUMAN,tr|F6R6M7|F6R6M7_HUMAN,tr|F6QYI9|F6QYI9_HUMAN,tr|A0A140T996|A0A140T996_HUMAN,tr|A0A0G2JJL7|A0A0G2JJL7_HUMAN,tr|A0A140T9L4|A0A140T9L4_HUMAN,tr|A0A140T9N3|A0A140T9N3_HUMAN,tr|A0A0G2JJZ9|A0A0G2JJZ9_HUMAN,tr|A0A140T9K1|A0A140T9K1_HUMAN,tr|K7EQN7|K7EQN7_HUMAN,tr|K7EN69|K7EN69_HUMAN,tr|A0A140T9X3|A0A140T9X3_HUMAN,tr|F6S4E6|F6S4E6_HUMAN,tr|A0A0A0MT12|A0A0A0MT12_HUMAN,tr|A0A0D9SEM9|A0A0D9SEM9_HUMAN" 22 942.5266 0.98 14718 14729 2 942.526447 472.2706 Spliceosome RNA helicase DDX39B OS=Homo sapiens OX=9606 GN=DDX39B PE=1 SV=1 6.1 2909.2 - 1.20E+06 - - - -0.1443 - 1.59 0.14 - 142.5 1 2 0 -0.0001 8 0 0 0 6.49E+07 6.59E+07 - - - 1.4736 0.9999 221125_WJC_METTL3_EV_vs_WT_F02.14730.14730.2 3.26E-06 20-Dec K.NFYYAAVPSAR[166.11].N sp|Q10471|GALT2_HUMAN 1 1267.6225 1.54 14719 14730 2 1267.621382 634.8185 Polypeptide N-acetylgalactosaminyltransferase 2 OS=Homo sapiens OX=9606 GN=GALNT2 PE=1 SV=1 8.59 2909.3 - 1.42E+06 - - - -0.8757 - 2.06 0.54 - 628.9 1 2 0 -0.0011 11 0 0 0 2.36E+08 1.54E+08 - - - 4.9842 0.9981 221125_WJC_METTL3_EV_vs_WT_F02.14731.14731.3 0.00794 Oct-36 R.MVNHFIAEFK[136.11].R "sp|P11142|HSP7C_HUMAN,tr|A8K7Q2|A8K7Q2_HUMAN,tr|E9PKE3|E9PKE3_HUMAN,tr|E9PN89|E9PN89_HUMAN" 4 1242.6311 0.16 14720 14731 3 1242.634502 415.2176 Heat shock cognate 71 kDa protein OS=Homo sapiens OX=9606 GN=HSPA8 PE=1 SV=1 6.5 2909.3 - 2.06E+06 - - - 2.7659 - 1.743 0.316 - 128.5 1 2 0 0.0034 10 0 0 0 1.50E+07 9.62E+07 - - - 3.6848 0.9999 221125_WJC_METTL3_EV_vs_WT_F02.14733.14733.2 0.000112 20-Nov R.LANIDEEMLQK[136.11].A sp|P54136|SYRC_HUMAN 1 1310.6632 0.69 14722 14733 2 1310.66419 656.3389 "Arginine--tRNA ligase, cytoplasmic OS=Homo sapiens OX=9606 GN=RARS1 PE=1 SV=2" 4.14 2909.5 - 860601 - - - 0.7912 - 2.732 0.466 - 560.4 1 2 0 0.001 11 0 0 0 4.42E+07 6.41E+07 - - - 5.2014 0.9996 221125_WJC_METTL3_EV_vs_WT_F02.14738.14738.2 0.000762 16-Sep K.LWDIGGQPR[166.11].F "sp|Q96BM9|ARL8A_HUMAN,sp|Q9NVJ2|ARL8B_HUMAN,tr|A0A087X2J2|A0A087X2J2_HUMAN" 3 1050.5486 0.24 14725 14738 2 1050.54685 526.2816 ADP-ribosylation factor-like protein 8A OS=Homo sapiens OX=9606 GN=ARL8A PE=1 SV=1 5.84 2910.1 - 1.44E+06 - - - -1.6648 - 1.949 0.395 - 259.4 1 2 0 -0.0017 9 0 0 0 1.98E+07 8.28E+07 - - - 3.8885 0.9983 221125_WJC_METTL3_EV_vs_WT_F02.14741.14741.2 0.00954 24-Sep K.LTSELLGEGAYAK.V "sp|Q9BUB5|MKNK1_HUMAN,tr|E9PN34|E9PN34_HUMAN,tr|A0A499FIS5|A0A499FIS5_HUMAN,tr|A0A499FJS1|A0A499FJS1_HUMAN,tr|E9PSE0|E9PSE0_HUMAN,tr|E9PIA0|E9PIA0_HUMAN,tr|E9PLE7|E9PLE7_HUMAN,tr|A0A499FJN1|A0A499FJN1_HUMAN,tr|E9PMM8|E9PMM8_HUMAN" 9 1350.7031 0.74 14728 14741 2 1350.706978 676.3588 MAP kinase-interacting serine\threonine-protein kinase 1 OS=Homo sapiens OX=9606 GN=MKNK1 PE=1 SV=1 4.53 2910.5 - 240930 - - - 2.8733 - 1.914 0.341 - 179.9 1 2 0 0.0039 13 0 0 0 2.44E+06 3.29E+06 - - - 3.2246 0.9998 221125_WJC_METTL3_EV_vs_WT_F02.14745.14745.2 6.32E-06 16-Sep K.YEWDVAEAR[166.11].K sp|P13639|EF2_HUMAN 1 1147.5174 0.54 14730 14745 2 1147.515637 574.766 Elongation factor 2 OS=Homo sapiens OX=9606 GN=EEF2 PE=1 SV=4 4.14 2911 - 3.38E+06 - - - -1.4998 - 1.797 0.613 - 314.2 1 2 0 -0.0017 9 0 0 0 1.17E+08 2.16E+08 - - - 5.2638 0.9987 221125_WJC_METTL3_EV_vs_WT_F02.14746.14746.3 0.0553 Sep-40 R.LGLIPIHADPR[166.11].L "sp|O15160|RPAC1_HUMAN,tr|D6RDJ3|D6RDJ3_HUMAN,tr|A0A2R8YEZ4|A0A2R8YEZ4_HUMAN,tr|H0Y723|H0Y723_HUMAN,tr|E7EQB9|E7EQB9_HUMAN,tr|A0A2R8Y5D3|A0A2R8Y5D3_HUMAN,tr|A0A2R8YEY5|A0A2R8YEY5_HUMAN,tr|A0A2R8Y8D6|A0A2R8Y8D6_HUMAN" 8 1210.7062 0.16 14731 14746 3 1210.705683 404.576 DNA-directed RNA polymerases I and III subunit RPAC1 OS=Homo sapiens OX=9606 GN=POLR1C PE=1 SV=1 6.74 2911.1 - 2.48E+06 - - - -0.3956 - 1.874 0.25 - 70.6 1 2 0 -0.0005 11 0 0 0 2.14E+07 1.37E+08 - - - 3.1114 1 221125_WJC_METTL3_EV_vs_WT_F02.14748.14748.2 2.16E-06 16/28 K.NQVAMNPTNTVFDAK[136.11].R "sp|P11142|HSP7C_HUMAN,tr|E9PQQ4|E9PQQ4_HUMAN,tr|E9PNE6|E9PNE6_HUMAN,tr|E9PKE3|E9PKE3_HUMAN,tr|E9PLF4|E9PLF4_HUMAN,tr|E9PK54|E9PK54_HUMAN,tr|E9PN25|E9PN25_HUMAN,tr|E9PPY6|E9PPY6_HUMAN,tr|E9PQK7|E9PQK7_HUMAN" 9 1656.8021 0.07 14733 14748 2 1656.801862 829.4083 Heat shock cognate 71 kDa protein OS=Homo sapiens OX=9606 GN=HSPA8 PE=1 SV=1 5.84 2911.3 - 364329 - - - -0.1473 - 2.959 0.667 - 686.9 1 2 0 -0.0002 15 0 0 0 1.14E+06 1.53E+07 - - - 6.6345 0.9942 221125_WJC_METTL3_EV_vs_WT_F02.14750.14750.2 0.0308 14-Jul R.ELAFQISK.E "sp|Q13838|DX39B_HUMAN,sp|O00148|DX39A_HUMAN,tr|K7EPJ3|K7EPJ3_HUMAN,tr|F6TRA5|F6TRA5_HUMAN,tr|F6WLT2|F6WLT2_HUMAN,tr|Q5STU3|Q5STU3_HUMAN,tr|A0A140T973|A0A140T973_HUMAN,tr|A0A140T9K2|A0A140T9K2_HUMAN,tr|F6R6M7|F6R6M7_HUMAN,tr|F6QYI9|F6QYI9_HUMAN,tr|A0A140T996|A0A140T996_HUMAN,tr|A0A0G2JJL7|A0A0G2JJL7_HUMAN,tr|A0A140T9L4|A0A140T9L4_HUMAN,tr|A0A140T9N3|A0A140T9N3_HUMAN,tr|A0A0G2JJZ9|A0A0G2JJZ9_HUMAN,tr|A0A140T9K1|A0A140T9K1_HUMAN,tr|K7EQN7|K7EQN7_HUMAN,tr|K7EN69|K7EN69_HUMAN,tr|A0A140T9X3|A0A140T9X3_HUMAN,tr|F6S4E6|F6S4E6_HUMAN,tr|A0A0A0MT12|A0A0A0MT12_HUMAN,tr|A0A0D9SEM9|A0A0D9SEM9_HUMAN" 22 934.5124 0.98 14734 14750 2 934.512394 468.2635 Spliceosome RNA helicase DDX39B OS=Homo sapiens OX=9606 GN=DDX39B PE=1 SV=1 6.1 2911.6 - 2.68E+06 - - - 0.0118 - 1.437 0.116 - 225.6 1 2 0 0 8 0 0 0 6.49E+07 6.59E+07 - - - 0.9912 0.9999 221125_WJC_METTL3_EV_vs_WT_F02.14752.14752.2 4.19E-05 20-Oct R.SVAGGFVYTYK.L sp|Q15393|SF3B3_HUMAN 1 1190.5972 1.08 14735 14752 2 1190.596668 596.3059 Splicing factor 3B subunit 3 OS=Homo sapiens OX=9606 GN=SF3B3 PE=1 SV=4 8.22 2911.8 - 6.49E+06 - - - -0.4258 - 2.095 0.497 - 211.5 1 2 0 -0.0005 11 0 0 0 1.40E+08 1.30E+08 - - - 4.7123 0.9992 221125_WJC_METTL3_EV_vs_WT_F02.14753.14753.2 0.0609 14-Aug R.ELLELASR.M "sp|Q00341|VIGLN_HUMAN,tr|A0A024R4E5|A0A024R4E5_HUMAN,tr|H0Y394|H0Y394_HUMAN" 3 929.5182 1.09 14736 14753 2 929.517524 465.7664 Vigilin OS=Homo sapiens OX=9606 GN=HDLBP PE=1 SV=2 4.53 2911.8 - 2.61E+06 - - - -0.723 - 1.787 0.248 - 254.6 1 2 0 -0.0007 8 0 0 0 6.99E+07 6.39E+07 - - - 2.6234 0.9997 221125_WJC_METTL3_EV_vs_WT_F02.14754.14754.2 0.000266 20-Aug R.SVAGGFVYTYK[136.11].L sp|Q15393|SF3B3_HUMAN 1 1198.6114 1.08 14737 14754 2 1198.612855 600.313 Splicing factor 3B subunit 3 OS=Homo sapiens OX=9606 GN=SF3B3 PE=1 SV=4 8.22 2911.9 - 6.14E+06 - - - 1.2348 - 1.788 0.47 - 114.3 1 2 0 0.0015 11 0 0 0 1.40E+08 1.30E+08 - - - 4.084 0.9996 221125_WJC_METTL3_EV_vs_WT_F02.14757.14757.2 1.58E-05 22-Dec K.LVC[160.03]TDIADVSVK.Q "sp|O43148|MCES_HUMAN,tr|K7EP06|K7EP06_HUMAN" 2 1318.6803 1.21 14740 14757 2 1318.683376 660.3474 mRNA cap guanine-N7 methyltransferase OS=Homo sapiens OX=9606 GN=RNMT PE=1 SV=1 4.21 2912.1 - 435471 - - - 2.3683 - 2.382 0.433 - 477.2 1 2 0 0.0031 12 0 0 0 5.82E+07 4.81E+07 - - - 4.5219 0.9908 221125_WJC_METTL3_EV_vs_WT_F02.14759.14759.2 0.36 22-Jun K.AIVIC[160.03]PTDEDLK[136.11].D "sp|Q9BUJ2|HNRL1_HUMAN,tr|A0A0A0MRA5|A0A0A0MRA5_HUMAN,tr|M0R3F1|M0R3F1_HUMAN,tr|B7Z4B8|B7Z4B8_HUMAN" 4 1380.705 19.47 14742 14759 2 1380.705602 691.3598 Heterogeneous nuclear ribonucleoprotein U-like protein 1 OS=Homo sapiens OX=9606 GN=HNRNPUL1 PE=1 SV=2 4.03 2912.4 - 141658 - - - 0.423 - 1.325 0.127 - 121.3 1 2 0 0.0006 12 0 0 0 4.23E+07 2.17E+06 - - - 0.7193 0.9965 221125_WJC_METTL3_EV_vs_WT_F02.14761.14761.2 0.531 14-Aug K.LLQLVEDR.G "sp|P17844|DDX5_HUMAN,tr|J3KTA4|J3KTA4_HUMAN,tr|A0A0G2JLI4|A0A0G2JLI4_HUMAN" 3 984.5604 1.56 14743 14761 2 984.561728 493.2875 Probable ATP-dependent RNA helicase DDX5 OS=Homo sapiens OX=9606 GN=DDX5 PE=1 SV=1 4.37 2912.6 - 1.58E+07 - - - 1.3539 - 1.695 0.145 - 215.8 1 2 0 0.0013 8 0 0 0 3.16E+09 2.02E+09 - - - 1.703 0.9996 221125_WJC_METTL3_EV_vs_WT_F02.14766.14766.2 0.00397 20-Dec R.LANIDEEMLQK.A sp|P54136|SYRC_HUMAN 1 1302.649 0.7 14747 14766 2 1302.646066 652.3318 "Arginine--tRNA ligase, cytoplasmic OS=Homo sapiens OX=9606 GN=RARS1 PE=1 SV=2" 4.14 2913 - 2.50E+06 - - - -2.2163 - 2.33 0.418 - 658.9 1 2 0 -0.0029 11 0 0 0 4.42E+07 6.33E+07 - - - 4.4157 0.9983 221125_WJC_METTL3_EV_vs_WT_F02.14768.14768.2 0.0014 20-Aug K.LVTDEDVFPTK.Y "sp|Q70IA6|MOB2_HUMAN,tr|A0A087WVS8|A0A087WVS8_HUMAN" 2 1262.6394 3.66 14749 14768 2 1262.643076 632.327 MOB kinase activator 2 OS=Homo sapiens OX=9606 GN=MOB2 PE=1 SV=1 4.03 2913.3 - 362124 - - - 2.8844 - 1.726 0.371 - 162.4 1 2 0 0.0036 11 0 0 0 2.71E+08 7.41E+07 - - - 3.2566 0.9996 221125_WJC_METTL3_EV_vs_WT_F02.14769.14769.2 0.218 18-Nov R.QFLESSELPR.A sp|O60749|SNX2_HUMAN 1 1204.6088 1.08 14750 14769 2 1204.610548 603.3117 Sorting nexin-2 OS=Homo sapiens OX=9606 GN=SNX2 PE=1 SV=2 4.53 2913.4 - 335558 - - - 1.4494 - 2.231 0.35 - 429.7 1 2 0 0.0017 10 0 0 0 2.11E+07 1.96E+07 - - - 3.8654 0.9999 221125_WJC_METTL3_EV_vs_WT_F02.14772.14772.2 9.02E-08 28-Nov K.QISNLQQSISDAEQR.G sp|P04264|K2C1_HUMAN 1 1715.8438 999 14753 14772 2 1715.845511 858.9292 "Keratin, type II cytoskeletal 1 OS=Homo sapiens OX=9606 GN=KRT1 PE=1 SV=6" 4.37 2913.8 - 199065 - - - 0.9733 - 2.408 0.596 - 178.5 1 2 0 0.0017 15 0 0 0 1.85E+06 0.00E+00 - - - 5.6031 0.9998 221125_WJC_METTL3_EV_vs_WT_F02.14774.14774.2 4.60E-05 18-Nov R.FPGQLNADLR[166.11].K "sp|P04350|TBB4A_HUMAN,sp|Q9BVA1|TBB2B_HUMAN,sp|A6NNZ2|TBB8B_HUMAN,sp|P07437|TBB5_HUMAN,sp|Q13509|TBB3_HUMAN,sp|Q13885|TBB2A_HUMAN,sp|P68371|TBB4B_HUMAN,sp|Q9BUF5|TBB6_HUMAN,sp|Q3ZCM7|TBB8_HUMAN,sp|Q9H4B7|TBB1_HUMAN,tr|M0R2D3|M0R2D3_HUMAN,tr|A0A0B4J269|A0A0B4J269_HUMAN,tr|Q5ST81|Q5ST81_HUMAN,tr|Q5JP53|Q5JP53_HUMAN,tr|K7ESM5|K7ESM5_HUMAN,tr|A0A075B736|A0A075B736_HUMAN,tr|G3V2A3|G3V2A3_HUMAN,tr|Q5SQY0|Q5SQY0_HUMAN" 18 1139.5963 0.76 14754 14774 2 1139.596959 570.8054 Tubulin beta-4A chain OS=Homo sapiens OX=9606 GN=TUBB4A PE=1 SV=2 5.84 2914 - 4.40E+06 - - - 0.5985 - 1.799 0.484 - 397.3 1 2 0 0.0007 10 0 0 0 3.16E+08 4.17E+08 - - - 4.2548 0.9998 221125_WJC_METTL3_EV_vs_WT_F02.14775.14775.2 3.75E-05 18-Nov R.FPGQLNADLR.K "sp|P04350|TBB4A_HUMAN,sp|Q9BVA1|TBB2B_HUMAN,sp|A6NNZ2|TBB8B_HUMAN,sp|P07437|TBB5_HUMAN,sp|Q13509|TBB3_HUMAN,sp|Q13885|TBB2A_HUMAN,sp|P68371|TBB4B_HUMAN,sp|Q9BUF5|TBB6_HUMAN,sp|Q3ZCM7|TBB8_HUMAN,sp|Q9H4B7|TBB1_HUMAN,tr|M0R2D3|M0R2D3_HUMAN,tr|A0A0B4J269|A0A0B4J269_HUMAN,tr|Q5ST81|Q5ST81_HUMAN,tr|Q5JP53|Q5JP53_HUMAN,tr|K7ESM5|K7ESM5_HUMAN,tr|A0A075B736|A0A075B736_HUMAN,tr|G3V2A3|G3V2A3_HUMAN,tr|Q5SQY0|Q5SQY0_HUMAN" 18 1129.588 -1 14755 14775 2 1129.588422 565.8013 Tubulin beta-4A chain OS=Homo sapiens OX=9606 GN=TUBB4A PE=1 SV=2 5.84 2914 - 3.75E+06 - - - 0.3674 - 1.904 0.463 - 435.8 1 2 0 0.0004 10 0 0 0 0.00E+00 0.00E+00 - - - 4.2581 0.9999 221125_WJC_METTL3_EV_vs_WT_F02.14777.14777.2 1.48E-05 16-Sep K.YEWDVAEAR.K sp|P13639|EF2_HUMAN 1 1137.5091 0.54 14757 14777 2 1137.509358 569.7618 Elongation factor 2 OS=Homo sapiens OX=9606 GN=EEF2 PE=1 SV=4 4.14 2914.1 - 5.16E+06 - - - 0.2374 - 1.744 0.563 - 346.8 1 2 0 0.0003 9 0 0 0 1.17E+08 2.16E+08 - - - 4.8083 0.9992 221125_WJC_METTL3_EV_vs_WT_F02.14780.14780.2 0.263 16-Aug R.TVLQMDELK[136.11].C sp|P42285|MTREX_HUMAN 1 1083.5725 0.96 14760 14780 2 1083.572865 542.7935 Exosome RNA helicase MTR4 OS=Homo sapiens OX=9606 GN=MTREX PE=1 SV=3 4.37 2914.3 - 1.86E+06 - - - 0.2935 - 1.633 0.289 - 163.3 1 2 0 0.0003 9 0 0 0 3.14E+07 3.28E+07 - - - 2.5943 0.9968 221125_WJC_METTL3_EV_vs_WT_F02.14782.14782.2 0.0213 20-Oct K.LSAMMGAVAEK[136.11].K "sp|Q86U44|MTA70_HUMAN,tr|F5H6D8|F5H6D8_HUMAN,tr|H0YFV6|H0YFV6_HUMAN,tr|B4DTN4|B4DTN4_HUMAN" 4 1114.5606 0 14762 14782 2 1114.557472 558.2876 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 6 2914.4 - 879329 - - - -2.8083 - 1.698 0.28 - 152 1 2 0 -0.0031 11 0 0 0 9.73E+04 2.83E+07 - - - 2.5404 0.9858 221125_WJC_METTL3_EV_vs_WT_F02.14784.14784.2 0.623 20-May R.LGLIPIHADPR[166.11].L "sp|O15160|RPAC1_HUMAN,tr|D6RDJ3|D6RDJ3_HUMAN,tr|A0A2R8YEZ4|A0A2R8YEZ4_HUMAN,tr|H0Y723|H0Y723_HUMAN,tr|E7EQB9|E7EQB9_HUMAN,tr|A0A2R8Y5D3|A0A2R8Y5D3_HUMAN,tr|A0A2R8YEY5|A0A2R8YEY5_HUMAN,tr|A0A2R8Y8D6|A0A2R8Y8D6_HUMAN" 8 1210.7062 0.17 14764 14784 2 1210.708032 606.3604 DNA-directed RNA polymerases I and III subunit RPAC1 OS=Homo sapiens OX=9606 GN=POLR1C PE=1 SV=1 6.74 2914.7 - 440260 - - - 1.5446 - 1.194 0.168 - 71.3 1 2 0 0.0019 11 0 0 0 2.00E+06 1.17E+07 - - - 0.7609 0.9995 221125_WJC_METTL3_EV_vs_WT_F02.14786.14786.2 3.67E-06 24-Oct R.LLSSSLTADC[160.03]SLR[166.11].S sp|Q147X3|NAA30_HUMAN 1 1431.7267 3.42 14766 14786 2 1431.730606 716.8706 N-alpha-acetyltransferase 30 OS=Homo sapiens OX=9606 GN=NAA30 PE=1 SV=1 5.83 2914.9 - 163421 - - - 2.7289 - 2.054 0.523 - 251.9 1 2 0 0.0039 13 0 0 0 5.05E+06 1.48E+06 - - - 4.75 0.9933 221125_WJC_METTL3_EV_vs_WT_F02.14789.14789.2 0.137 18-May R.SMQDVVEDFK.N sp|P08729|K2C7_HUMAN 1 1196.5383 72.43 14767 14789 2 1196.537946 599.2764 "Keratin, type II cytoskeletal 7 OS=Homo sapiens OX=9606 GN=KRT7 PE=1 SV=5" 4.03 2915.3 - 6.16E+06 - - - -0.3284 - 1.013 0.246 - 86.4 1 2 0 -0.0004 10 0 0 0 3.69E+08 5.09E+06 - - - 0.8939 0.9994 221125_WJC_METTL3_EV_vs_WT_F02.14790.14790.2 0.162 14-Sep K.ELEEWYAR[166.11].Q "sp|P09496|CLCA_HUMAN,tr|F8WF69|F8WF69_HUMAN,tr|C9J8P9|C9J8P9_HUMAN" 3 1104.5115 0.57 14768 14790 2 1104.511339 553.263 Clathrin light chain A OS=Homo sapiens OX=9606 GN=CLTA PE=1 SV=1 4.25 2915.4 - 3.52E+06 - - - -0.1865 - 1.563 0.342 - 469.8 1 2 0 -0.0002 8 0 0 0 7.67E+07 1.34E+08 - - - 2.9139 0.9991 221125_WJC_METTL3_EV_vs_WT_F02.14791.14791.2 0.056 16-Sep R.TVLQMDELK.C sp|P42285|MTREX_HUMAN 1 1075.5583 0.96 14769 14791 2 1075.556828 538.7864 Exosome RNA helicase MTR4 OS=Homo sapiens OX=9606 GN=MTREX PE=1 SV=3 4.37 2915.4 - 2.11E+06 - - - -1.4123 - 1.648 0.314 - 246.5 1 2 0 -0.0015 9 0 0 0 3.15E+07 3.28E+07 - - - 2.805 0.9966 221125_WJC_METTL3_EV_vs_WT_F02.14796.14796.2 0.0342 12-Jun R.SVPTWLK.L "sp|P62277|RS13_HUMAN,tr|J3KMX5|J3KMX5_HUMAN,tr|E9PS50|E9PS50_HUMAN" 3 829.4698 0.94 14772 14796 2 829.468969 415.7422 40S ribosomal protein S13 OS=Homo sapiens OX=9606 GN=RPS13 PE=1 SV=2 8.47 2916 - 9.76E+06 - - - -0.9898 - 1.342 0.209 - 106.6 1 2 0 -0.0008 7 0 0 0 6.37E+08 6.78E+08 - - - 1.5165 0.9998 221125_WJC_METTL3_EV_vs_WT_F02.14799.14799.2 3.49E-05 24-Dec K.LLVPAAEGEDSLK.K "sp|Q96PU8|QKI_HUMAN,tr|F5GYM3|F5GYM3_HUMAN,tr|F5GXS8|F5GXS8_HUMAN,tr|H0YG47|H0YG47_HUMAN,tr|H0YGD6|H0YGD6_HUMAN" 5 1340.7187 2.24 14775 14799 2 1340.717619 671.3666 Protein quaking OS=Homo sapiens OX=9606 GN=QKI PE=1 SV=1 4.14 2916.3 - 1.31E+06 - - - -0.8413 - 1.868 0.531 - 359.4 1 2 0 -0.0011 13 0 0 0 4.09E+08 1.83E+08 - - - 4.5664 0.9999 221125_WJC_METTL3_EV_vs_WT_F02.14803.14803.2 7.65E-08 18-Oct R.DGAGDVAFIR.E "sp|P02788|TRFL_HUMAN,tr|E7EQB2|E7EQB2_HUMAN,tr|E7ER44|E7ER44_HUMAN" 3 1019.5036 40.41 14777 14803 2 1019.503568 510.7591 Lactotransferrin OS=Homo sapiens OX=9606 GN=LTF PE=1 SV=6 4.21 2916.8 - 2.53E+06 - - - -0.0402 - 2.217 0.581 - 469.3 1 2 0 0 10 0 0 0 7.15E+07 1.77E+06 - - - 5.5546 0.9999 221125_WJC_METTL3_EV_vs_WT_F02.14804.14804.2 2.24E-07 13/24 K.LLVPAAEGEDSLK[136.11].K "sp|Q96PU8|QKI_HUMAN,tr|F5GYM3|F5GYM3_HUMAN,tr|F5GXS8|F5GXS8_HUMAN,tr|H0YG47|H0YG47_HUMAN,tr|H0YGD6|H0YGD6_HUMAN" 5 1348.7329 2.24 14778 14804 2 1348.732707 675.3737 Protein quaking OS=Homo sapiens OX=9606 GN=QKI PE=1 SV=1 4.14 2916.9 - 1.38E+06 - - - -0.1779 - 2.094 0.591 - 442.5 1 2 0 -0.0002 13 0 0 0 4.09E+08 1.83E+08 - - - 5.3029 0.9995 221125_WJC_METTL3_EV_vs_WT_F02.14805.14805.2 0.00565 18-Nov K.QQLLIGAYAK[136.11].A sp|Q99832|TCPH_HUMAN 1 1111.6481 0.17 14779 14805 2 1111.648877 556.8313 T-complex protein 1 subunit eta OS=Homo sapiens OX=9606 GN=CCT7 PE=1 SV=2 8.59 2917 - 1.01E+06 - - - 0.7035 - 2.046 0.289 - 405.5 1 2 0 0.0008 10 0 0 0 2.11E+08 1.23E+09 - - - 3.1736 0.9999 221125_WJC_METTL3_EV_vs_WT_F02.14807.14807.2 7.12E-06 18-Dec R.QFLESSELPR[166.11].A sp|O60749|SNX2_HUMAN 1 1214.6171 1.28 14781 14807 2 1214.617463 608.3158 Sorting nexin-2 OS=Homo sapiens OX=9606 GN=SNX2 PE=1 SV=2 4.53 2917.2 - 822541 - - - 0.3219 - 2.513 0.534 - 518.3 1 2 0 0.0004 10 0 0 0 2.00E+07 1.56E+07 - - - 5.5571 0.9986 221125_WJC_METTL3_EV_vs_WT_F02.14811.14811.2 0.421 14-Sep R.NLLSVAYK[136.11].N "sp|P31946|1433B_HUMAN,sp|P62258|1433E_HUMAN,sp|P27348|1433T_HUMAN,sp|P63104|1433Z_HUMAN,sp|Q04917|1433F_HUMAN,sp|P31947|1433S_HUMAN,sp|P61981|1433G_HUMAN,tr|E7EX29|E7EX29_HUMAN,tr|Q4VY19|Q4VY19_HUMAN,tr|B4DJF2|B4DJF2_HUMAN,tr|A0A0J9YWZ2|A0A0J9YWZ2_HUMAN,tr|Q4VY20|Q4VY20_HUMAN,tr|A2IDB2|A2IDB2_HUMAN,tr|E5RIR4|E5RIR4_HUMAN,tr|E9PG15|E9PG15_HUMAN,tr|I3L3T1|I3L3T1_HUMAN,tr|K7EIT4|K7EIT4_HUMAN,tr|E7EVZ2|E7EVZ2_HUMAN,tr|E5RGE1|E5RGE1_HUMAN,tr|E9PD24|E9PD24_HUMAN,tr|A0A0J9YWE8|A0A0J9YWE8_HUMAN,tr|E7ESK7|E7ESK7_HUMAN" 22 914.5317 1.12 14783 14811 2 914.530147 458.2731 14-3-3 protein beta\alpha OS=Homo sapiens OX=9606 GN=YWHAB PE=1 SV=3 8.59 2917.7 - 7.59E+06 - - - -1.6631 - 1.622 0.276 - 287.8 1 2 0 -0.0015 8 0 0 0 1.45E+09 1.30E+09 - - - 2.5378 0.9997 221125_WJC_METTL3_EV_vs_WT_F02.14812.14812.2 0.00358 16-Sep K.VELDNMPLR.G "sp|Q15233|NONO_HUMAN,tr|A0A7I2V535|A0A7I2V535_HUMAN,tr|A0A7I2V4N2|A0A7I2V4N2_HUMAN,tr|A0A7I2V4K9|A0A7I2V4K9_HUMAN,tr|A0A7I2V464|A0A7I2V464_HUMAN,tr|A0A7P0MRW0|A0A7P0MRW0_HUMAN,tr|C9IZL7|C9IZL7_HUMAN,tr|C9J4X2|C9J4X2_HUMAN,tr|A0A7I2V4J2|A0A7I2V4J2_HUMAN,tr|A0A7I2V5Y7|A0A7I2V5Y7_HUMAN,tr|C9JYS8|C9JYS8_HUMAN" 11 1085.5539 1.04 14784 14812 2 1085.553372 543.7842 Non-POU domain-containing octamer-binding protein OS=Homo sapiens OX=9606 GN=NONO PE=1 SV=4 4.37 2917.7 - 3.72E+06 - - - -0.514 - 1.843 0.373 - 375.8 1 2 0 -0.0006 9 0 0 0 3.57E+08 3.44E+08 - - - 3.5646 0.999 221125_WJC_METTL3_EV_vs_WT_F02.14813.14813.2 0.0613 20-Sep R.LLGFGGGGEAR.Q "tr|E5RFD1|E5RFD1_HUMAN,tr|C9JY63|C9JY63_HUMAN" 2 1032.5352 0.81 14785 14813 2 1032.53565 517.2749 Oxidation resistance protein 1 OS=Homo sapiens OX=9606 GN=OXR1 PE=1 SV=1 6 2917.8 - 2.46E+06 - - - 0.3942 - 1.61 0.289 - 210.5 1 2 0 0.0004 11 0 0 0 5.52E+07 6.84E+07 - - - 2.4638 0.9991 221125_WJC_METTL3_EV_vs_WT_F02.14814.14814.2 0.0945 14-Aug K.AAFAPFGR[166.11].L "sp|P31483|TIA1_HUMAN,tr|F8W8I6|F8W8I6_HUMAN,tr|C9JTN7|C9JTN7_HUMAN,tr|H7BY49|H7BY49_HUMAN,tr|E5RGV5|E5RGV5_HUMAN" 5 845.4423 1.74 14786 14814 2 845.441979 423.7284 Nucleolysin TIA-1 isoform p40 OS=Homo sapiens OX=9606 GN=TIA1 PE=1 SV=3 9.79 2917.8 - 1.42E+06 - - - -0.4305 - 1.644 0.259 - 229.5 1 2 0 -0.0004 8 0 0 0 1.32E+08 7.61E+07 - - - 2.4532 0.9998 221125_WJC_METTL3_EV_vs_WT_F02.14817.14817.2 0.00317 14-Jul R.YDVYLYDR[166.11].L "sp|Q9Y6Y8|S23IP_HUMAN,tr|H7C4C4|H7C4C4_HUMAN,tr|H7C0V8|H7C0V8_HUMAN" 3 1115.5163 5.27 14789 14817 2 1115.516096 558.7654 SEC23-interacting protein OS=Homo sapiens OX=9606 GN=SEC23IP PE=1 SV=1 4.21 2918.1 - 1.02E+06 - - - -0.1793 - 1.582 0.473 - 140.6 1 2 0 -0.0002 8 0 0 0 5.92E+07 1.12E+07 - - - 3.9179 0.9966 221125_WJC_METTL3_EV_vs_WT_F02.14823.14823.2 0.376 18-Aug K.YIETTPLTIK[136.11].G sp|Q14966|ZN638_HUMAN 1 1185.6736 0.86 14793 14823 2 1185.67313 593.8441 Zinc finger protein 638 OS=Homo sapiens OX=9606 GN=ZNF638 PE=1 SV=2 6 2918.8 - 2.01E+06 - - - -0.431 - 1.403 0.191 - 123.6 1 2 0 -0.0005 10 0 0 0 4.28E+07 4.97E+07 - - - 1.3967 0.9983 221125_WJC_METTL3_EV_vs_WT_F02.14824.14824.2 0.0294 12-Jul R.LDLLEDR[166.11].S "sp|Q14697|GANAB_HUMAN,tr|E9PNH1|E9PNH1_HUMAN,tr|E9PKU7|E9PKU7_HUMAN,tr|F5H6X6|F5H6X6_HUMAN" 4 882.4686 0.99 14794 14824 2 882.467681 442.2416 Neutral alpha-glucosidase AB OS=Homo sapiens OX=9606 GN=GANAB PE=1 SV=3 4.03 2918.9 - 1.65E+06 - - - -1.0607 - 1.643 0.201 - 170.6 1 2 0 -0.0009 7 0 0 0 4.06E+07 4.11E+07 - - - 2.0986 0.9995 221125_WJC_METTL3_EV_vs_WT_F02.14825.14825.2 0.00102 18-Dec R.VVGTIDQLVK.R "sp|Q8IX01|SUGP2_HUMAN,tr|M0R2Z9|M0R2Z9_HUMAN,tr|M0R3F6|M0R3F6_HUMAN" 3 1070.6336 1.35 14795 14825 2 1070.630962 536.3241 SURP and G-patch domain-containing protein 2 OS=Homo sapiens OX=9606 GN=SUGP2 PE=1 SV=2 5.81 2919 - 1.18E+06 - - - -2.4266 - 2.042 0.45 - 375.8 1 2 0 -0.0026 10 0 0 0 6.27E+07 4.66E+07 - - - 4.3567 0.9994 221125_WJC_METTL3_EV_vs_WT_F02.14831.14831.2 0.000206 20-Oct K.LVTDEDVFPTK[136.11].Y "sp|Q70IA6|MOB2_HUMAN,tr|A0A087WVS8|A0A087WVS8_HUMAN" 2 1270.6536 3.65 14799 14831 2 1270.656861 636.3341 MOB kinase activator 2 OS=Homo sapiens OX=9606 GN=MOB2 PE=1 SV=1 4.03 2919.6 - 2.49E+06 - - - 2.5396 - 1.902 0.479 - 270 1 2 0 0.0032 11 0 0 0 2.71E+08 7.41E+07 - - - 4.3171 0.9999 221125_WJC_METTL3_EV_vs_WT_F02.14834.14834.2 0.000746 24-Dec K.LIAEEGVDSLNVK[136.11].E sp|O95202|LETM1_HUMAN 1 1393.7544 0.48 14802 14834 2 1393.752671 697.8845 Mitochondrial proton\calcium exchanger protein OS=Homo sapiens OX=9606 GN=LETM1 PE=1 SV=1 4.14 2920 - 353623 - - - -1.2477 - 2.437 0.529 - 366.8 1 2 0 -0.0017 13 0 0 0 5.54E+06 1.15E+07 - - - 5.2338 0.959 221125_WJC_METTL3_EV_vs_WT_F02.14846.14846.2 0.869 14-Jul R.DLPNIEVR.L "sp|P26358|DNMT1_HUMAN,tr|A0A7I2V5D0|A0A7I2V5D0_HUMAN,tr|A0A7I2V5F1|A0A7I2V5F1_HUMAN,tr|A0A7I2YQA8|A0A7I2YQA8_HUMAN,tr|A0A7I2YQQ0|A0A7I2YQQ0_HUMAN,tr|K7ENW7|K7ENW7_HUMAN,tr|A0A7I2V490|A0A7I2V490_HUMAN" 7 954.5134 0.79 14811 14846 2 954.513324 478.264 DNA (cytosine-5)-methyltransferase 1 OS=Homo sapiens OX=9606 GN=DNMT1 PE=1 SV=2 4.37 2921.4 - 681624 - - - -0.1268 - 1.224 0.005 - 119.9 1 2 0 -0.0001 8 0 0 0 1.15E+07 1.45E+07 - - - -0.3125 0.9998 221125_WJC_METTL3_EV_vs_WT_F02.14848.14848.2 0.00546 16-Sep K.YYAVNYPLR[166.11].D "sp|Q13547|HDAC1_HUMAN,tr|Q5TEE2|Q5TEE2_HUMAN" 2 1167.5952 1.44 14812 14848 2 1167.594722 584.8049 Histone deacetylase 1 OS=Homo sapiens OX=9606 GN=HDAC1 PE=1 SV=1 8.5 2921.6 - 5.10E+06 - - - -0.4222 - 1.784 0.482 - 249.5 1 2 0 -0.0005 9 0 0 0 1.04E+08 7.20E+07 - - - 4.2756 0.9996 221125_WJC_METTL3_EV_vs_WT_F02.14849.14849.2 0.0108 16-Sep K.GDFITIGSR[166.11].K "sp|Q53H12|AGK_HUMAN,tr|E9PC15|E9PC15_HUMAN,tr|A0A3B3ITD0|A0A3B3ITD0_HUMAN,tr|A0A3B3ISY9|A0A3B3ISY9_HUMAN,tr|A0A0G2JLG5|A0A0G2JLG5_HUMAN" 5 974.5061 1.05 14813 14849 2 974.505644 488.2603 "Acylglycerol kinase, mitochondrial OS=Homo sapiens OX=9606 GN=AGK PE=1 SV=2" 5.84 2921.6 - 1.56E+06 - - - -0.432 - 1.68 0.379 - 247.3 1 2 0 -0.0004 9 0 0 0 2.66E+07 2.53E+07 - - - 3.3411 0.9996 221125_WJC_METTL3_EV_vs_WT_F02.14850.14850.2 0.0332 18-Sep K.YIETTPLTIK.G sp|Q14966|ZN638_HUMAN 1 1177.6594 0.86 14814 14850 2 1177.659174 589.837 Zinc finger protein 638 OS=Homo sapiens OX=9606 GN=ZNF638 PE=1 SV=2 6 2921.7 - 2.80E+06 - - - -0.2267 - 1.588 0.391 - 179.2 1 2 0 -0.0003 10 0 0 0 4.26E+07 4.97E+07 - - - 3.2198 0.9985 221125_WJC_METTL3_EV_vs_WT_F02.14853.14853.2 0.0108 16-Sep R.SLSAIYLEK.L "sp|Q15149|PLEC_HUMAN,tr|H0YDN1|H0YDN1_HUMAN" 2 1022.5648 1.83 14817 14853 2 1022.563718 512.2897 Plectin OS=Homo sapiens OX=9606 GN=PLEC PE=1 SV=3 5.72 2921.9 - 712227 - - - -1.0699 - 1.547 0.254 - 193.3 1 2 0 -0.0011 9 0 0 0 2.76E+07 1.51E+07 - - - 2.179 0.9996 221125_WJC_METTL3_EV_vs_WT_F02.14856.14856.2 0.0175 18-Oct K.QQLLIGAYAK.A sp|Q99832|TCPH_HUMAN 1 1103.6339 0.17 14818 14856 2 1103.63296 552.8242 T-complex protein 1 subunit eta OS=Homo sapiens OX=9606 GN=CCT7 PE=1 SV=2 8.59 2922.3 - 6.35E+06 - - - -0.8472 - 1.839 0.36 - 379.2 1 2 0 -0.0009 10 0 0 0 2.13E+08 1.23E+09 - - - 3.4002 0.9485 221125_WJC_METTL3_EV_vs_WT_F02.14857.14857.2 0.936 18-Jul R.VEAGAGLGTR.- tr|K7EIZ3|K7EIZ3_HUMAN 1 929.493 5.93 14819 14857 2 929.491787 465.7538 Pleckstrin homology domain-containing family J member 1 OS=Homo sapiens OX=9606 GN=PLEKHJ1 PE=1 SV=1 5.97 2922.4 - 724401 - - - -1.3524 - 1.323 0.055 - 64.6 11 2 0 -0.0013 10 0 0 0 1.03E+07 1.73E+06 - - - -0.2371 0.9988 221125_WJC_METTL3_EV_vs_WT_F02.14861.14861.2 0.0118 22-Aug K.AEPPQAMNALMR.L sp|Q12906|ILF3_HUMAN 1 1327.6377 0.96 14823 14861 2 1327.635596 664.8261 Interleukin enhancer-binding factor 3 OS=Homo sapiens OX=9606 GN=ILF3 PE=1 SV=3 6.05 2922.9 - 687778 - - - -1.5667 - 1.463 0.355 - 95.7 1 2 0 -0.0021 12 0 0 0 1.09E+07 1.14E+07 - - - 2.6635 0.9984 221125_WJC_METTL3_EV_vs_WT_F02.14866.14866.2 0.0943 14-Jul R.NLLSVAYK.N "sp|P31946|1433B_HUMAN,sp|P62258|1433E_HUMAN,sp|P27348|1433T_HUMAN,sp|P63104|1433Z_HUMAN,sp|Q04917|1433F_HUMAN,sp|P31947|1433S_HUMAN,sp|P61981|1433G_HUMAN,tr|E7EX29|E7EX29_HUMAN,tr|Q4VY19|Q4VY19_HUMAN,tr|B4DJF2|B4DJF2_HUMAN,tr|A0A0J9YWZ2|A0A0J9YWZ2_HUMAN,tr|Q4VY20|Q4VY20_HUMAN,tr|A2IDB2|A2IDB2_HUMAN,tr|E5RIR4|E5RIR4_HUMAN,tr|E9PG15|E9PG15_HUMAN,tr|I3L3T1|I3L3T1_HUMAN,tr|K7EIT4|K7EIT4_HUMAN,tr|E7EVZ2|E7EVZ2_HUMAN,tr|E5RGE1|E5RGE1_HUMAN,tr|E9PD24|E9PD24_HUMAN,tr|A0A0J9YWE8|A0A0J9YWE8_HUMAN,tr|E7ESK7|E7ESK7_HUMAN" 22 906.5175 1.12 14826 14866 2 906.516955 454.266 14-3-3 protein beta\alpha OS=Homo sapiens OX=9606 GN=YWHAB PE=1 SV=3 8.59 2923.6 - 9.69E+07 - - - -0.5659 - 1.376 0.271 - 162.1 1 2 0 -0.0005 8 0 0 0 1.46E+09 1.30E+09 - - - 2.0051 0.9908 221125_WJC_METTL3_EV_vs_WT_F02.14871.14871.2 0.663 12-Jun K.LTLTFNR.T sp|P36542|ATPG_HUMAN 1 863.4865 1.09 14831 14871 2 863.484344 432.7505 "ATP synthase subunit gamma, mitochondrial OS=Homo sapiens OX=9606 GN=ATP5F1C PE=1 SV=1" 9.75 2923.8 - 2.61E+06 - - - -2.4992 - 1.355 0.2 - 130 1 2 0 -0.0022 7 0 0 0 2.91E+08 2.67E+08 - - - 1.4801 0.9997 221125_WJC_METTL3_EV_vs_WT_F02.14872.14872.2 0.00983 20-Oct R.VGVVGLPNVGK[136.11].S "sp|Q9NVN8|GNL3L_HUMAN,tr|A0A6I8PL80|A0A6I8PL80_HUMAN,tr|A0A6I8PS19|A0A6I8PS19_HUMAN" 3 1045.6375 2.1 14832 14872 2 1045.637813 523.826 Guanine nucleotide-binding protein-like 3-like protein OS=Homo sapiens OX=9606 GN=GNL3L PE=1 SV=1 8.72 2923.9 - 1.89E+06 - - - 0.2706 - 1.864 0.405 - 259.7 1 2 0 0.0003 11 0 0 0 7.41E+07 3.53E+07 - - - 3.7169 0.9995 221125_WJC_METTL3_EV_vs_WT_F02.14873.14873.3 0.0069 Dec-36 K.LAELEEALQK.A "sp|P13647|K2C5_HUMAN,tr|H0YI76|H0YI76_HUMAN" 2 1142.6183 19.65 14833 14873 3 1142.616841 381.88 "Keratin, type II cytoskeletal 5 OS=Homo sapiens OX=9606 GN=KRT5 PE=1 SV=3" 4.25 2924 - 1.57E+06 - - - -1.2804 - 2.003 0.296 - 205.8 1 2 0 -0.0015 10 0 0 0 3.02E+07 1.54E+06 - - - 3.8684 0.9993 221125_WJC_METTL3_EV_vs_WT_F02.14879.14879.2 0.0648 16-Aug K.TVTLVEAIK[136.11].Q "sp|Q9HCE1|MOV10_HUMAN,tr|Q5JR04|Q5JR04_HUMAN" 2 980.5997 0.94 14838 14879 2 980.5997 491.3072 Helicase MOV-10 OS=Homo sapiens OX=9606 GN=MOV10 PE=1 SV=2 5.66 2924.7 - 165749 - - - -0.0489 - 1.596 0.32 - 168.8 1 2 0 0 9 0 0 0 8.87E+06 9.44E+06 - - - 2.757 0.9995 221125_WJC_METTL3_EV_vs_WT_F02.14881.14881.2 0.000126 20-Oct K.SLGLSDEEIVK.F "sp|Q9P2J5|SYLC_HUMAN,tr|A0A6I8PIV1|A0A6I8PIV1_HUMAN,tr|A0A6I8PRS0|A0A6I8PRS0_HUMAN,tr|A0A6I8PLB8|A0A6I8PLB8_HUMAN,tr|A0A6I8PIP7|A0A6I8PIP7_HUMAN,tr|A0A6I8PIT3|A0A6I8PIT3_HUMAN,tr|A0A6I8PTV8|A0A6I8PTV8_HUMAN,tr|A0A6I8PRU9|A0A6I8PRU9_HUMAN,tr|A0A6I8PLB3|A0A6I8PLB3_HUMAN,tr|A0A6I8PS05|A0A6I8PS05_HUMAN,tr|B4DER1|B4DER1_HUMAN,tr|A0A6I8PL42|A0A6I8PL42_HUMAN" 12 1188.6238 1.73 14840 14881 2 1188.623436 595.3192 "Leucine--tRNA ligase, cytoplasmic OS=Homo sapiens OX=9606 GN=LARS1 PE=1 SV=2" 4.14 2924.8 - 2.31E+06 - - - -0.2928 - 2.054 0.275 - 227.5 1 2 0 -0.0003 11 0 0 0 7.00E+07 4.04E+07 - - - 3.0192 0.9834 221125_WJC_METTL3_EV_vs_WT_F02.14882.14882.2 0.47 16-Jul K.FPDSVEELR.A sp|Q15785|TOM34_HUMAN 1 1090.5295 1.55 14841 14882 2 1090.527543 546.272 Mitochondrial import receptor subunit TOM34 OS=Homo sapiens OX=9606 GN=TOMM34 PE=1 SV=2 4.14 2924.8 - 7.28E+06 - - - -1.7845 - 1.147 0.17 - 96.4 1 2 0 -0.0019 9 0 0 0 1.98E+08 1.28E+08 - - - 0.6928 0.9995 221125_WJC_METTL3_EV_vs_WT_F02.14883.14883.2 0.000166 14-Jul R.LLWAGDDR.G tr|A0A087X091|A0A087X091_HUMAN 1 944.4716 0.72 14842 14883 2 944.470456 473.2431 WD repeat-containing protein 13 (Fragment) OS=Homo sapiens OX=9606 GN=WDR13 PE=1 SV=1 4.21 2924.9 - 1.47E+06 - - - -1.1901 - 1.599 0.392 - 141.3 1 2 0 -0.0011 8 0 0 0 3.12E+07 4.34E+07 - - - 3.3516 0.9921 221125_WJC_METTL3_EV_vs_WT_F02.14890.14890.2 0.191 12-May R.SVPTWLK[136.11].L "sp|P62277|RS13_HUMAN,tr|J3KMX5|J3KMX5_HUMAN,tr|E9PS50|E9PS50_HUMAN" 3 837.484 0.94 14848 14890 2 837.482782 419.7493 40S ribosomal protein S13 OS=Homo sapiens OX=9606 GN=RPS13 PE=1 SV=2 8.47 2925.6 - 1.91E+07 - - - -1.4424 - 1.04 0.257 - 69.8 1 2 0 -0.0012 7 0 0 0 6.37E+08 6.78E+08 - - - 1.0631 0.9998 221125_WJC_METTL3_EV_vs_WT_F02.14892.14892.2 0.000116 14-Oct R.C[160.03]FLVYSER.T "sp|Q8IY67|RAVR1_HUMAN,tr|E9PAU2|E9PAU2_HUMAN,tr|A0A087WZ13|A0A087WZ13_HUMAN" 3 1072.5012 0.73 14849 14892 2 1072.500484 537.2579 Ribonucleoprotein PTB-binding 1 OS=Homo sapiens OX=9606 GN=RAVER1 PE=1 SV=1 5.99 2925.8 - 6.62E+06 - - - -0.6359 - 1.882 0.459 - 507.3 1 2 0 -0.0007 8 0 0 0 1.01E+08 1.38E+08 - - - 4.3381 0.9988 221125_WJC_METTL3_EV_vs_WT_F02.14893.14893.2 0.465 16-Sep R.SIGEYDVLR[166.11].G sp|P78527|PRKDC_HUMAN 1 1060.5428 0.66 14850 14893 2 1060.543598 531.2787 DNA-dependent protein kinase catalytic subunit OS=Homo sapiens OX=9606 GN=PRKDC PE=1 SV=3 4.37 2925.9 - 3.01E+06 - - - 0.71 - 1.585 0.265 - 227.5 1 2 0 0.0008 9 0 0 0 3.49E+07 5.26E+07 - - - 2.3305 0.9996 221125_WJC_METTL3_EV_vs_WT_F02.14894.14894.2 2.83E-06 20-Oct R.IGGGIDVPVPR[166.11].H "sp|Q92945|FUBP2_HUMAN,tr|M0R0I5|M0R0I5_HUMAN,tr|M0R0C6|M0R0C6_HUMAN,tr|A0A087WTP3|A0A087WTP3_HUMAN" 4 1088.6218 1.18 14851 14894 2 1088.619764 545.3182 Far upstream element-binding protein 2 OS=Homo sapiens OX=9606 GN=KHSRP PE=1 SV=4 5.84 2925.9 - 8.42E+06 - - - -1.8372 - 2.258 0.37 - 272.7 1 2 0 -0.002 11 0 0 0 3.87E+08 3.27E+08 - - - 3.9766 0.9998 221125_WJC_METTL3_EV_vs_WT_F02.14896.14896.2 0.00015 22-Dec K.LLLSSETPIEGK[136.11].N "sp|Q9HDC9|APMAP_HUMAN,tr|H0Y512|H0Y512_HUMAN" 2 1293.7271 1.18 14853 14896 2 1293.728814 647.8708 Adipocyte plasma membrane-associated protein OS=Homo sapiens OX=9606 GN=APMAP PE=1 SV=2 4.53 2926.1 - 985265 - - - 1.2993 - 2.298 0.486 - 415.3 1 2 0 0.0017 12 0 0 0 9.94E+07 8.39E+07 - - - 4.8193 0.7885 221125_WJC_METTL3_EV_vs_WT_F02.14901.14901.2 0.0832 16-Jul P.VLVIYEDSK.R sp|A0A075B6K4|LV310_HUMAN 1 1064.5754 42.72 14856 14901 2 1064.572717 533.295 Immunoglobulin lambda variable 3-10 OS=Homo sapiens OX=9606 GN=IGLV3-10 PE=3 SV=2 4.37 2926.7 - 3.66E+06 - - - -2.4986 - 1.41 0.274 - 164.5 1 1 0 -0.0027 9 0 0 0 1.77E+08 4.15E+06 - - - 2.058 0.9679 221125_WJC_METTL3_EV_vs_WT_F02.14903.14903.2 0.551 16-Jul K.LLIIGTTSR[166.11].K "sp|P46459|NSF_HUMAN,tr|K7EQD6|K7EQD6_HUMAN,tr|I3L0N3|I3L0N3_HUMAN,tr|I3L2G1|I3L2G1_HUMAN" 4 982.6051 0.9 14858 14903 2 982.602986 492.3098 Vesicle-fusing ATPase OS=Homo sapiens OX=9606 GN=NSF PE=1 SV=3 9.75 2926.9 - 420606 - - - -2.1016 - 1.508 0.04 - 115.2 2 2 0 -0.0021 9 0 0 0 1.58E+07 1.75E+07 - - - 0.3897 0.998 221125_WJC_METTL3_EV_vs_WT_F02.14911.14911.2 0.0231 20-Aug K.SLGLSDEEIVK[136.11].F "sp|Q9P2J5|SYLC_HUMAN,tr|A0A6I8PIV1|A0A6I8PIV1_HUMAN,tr|A0A6I8PRS0|A0A6I8PRS0_HUMAN,tr|A0A6I8PLB8|A0A6I8PLB8_HUMAN,tr|A0A6I8PIP7|A0A6I8PIP7_HUMAN,tr|A0A6I8PIT3|A0A6I8PIT3_HUMAN,tr|A0A6I8PTV8|A0A6I8PTV8_HUMAN,tr|A0A6I8PRU9|A0A6I8PRU9_HUMAN,tr|A0A6I8PLB3|A0A6I8PLB3_HUMAN,tr|A0A6I8PS05|A0A6I8PS05_HUMAN,tr|B4DER1|B4DER1_HUMAN,tr|A0A6I8PL42|A0A6I8PL42_HUMAN" 12 1196.638 1.63 14864 14911 2 1196.635711 599.3263 "Leucine--tRNA ligase, cytoplasmic OS=Homo sapiens OX=9606 GN=LARS1 PE=1 SV=2" 4.14 2927.9 - 2.47E+06 - - - -1.8995 - 1.7 0.256 - 131.3 1 2 0 -0.0023 11 0 0 0 6.54E+07 4.00E+07 - - - 2.3666 0.9929 221125_WJC_METTL3_EV_vs_WT_F02.14912.14912.2 0.233 14-Jun K.SQPMGLWR.Q "sp|P25311|ZA2G_HUMAN,tr|H7BZJ8|H7BZJ8_HUMAN,tr|C9JEV0|C9JEV0_HUMAN" 3 973.4804 69.05 14865 14912 2 973.478913 487.7475 Zinc-alpha-2-glycoprotein OS=Homo sapiens OX=9606 GN=AZGP1 PE=1 SV=2 9.47 2928 - 1.24E+06 - - - -1.4977 - 1.281 0.187 - 157 1 2 0 -0.0015 8 0 0 0 4.43E+07 6.42E+05 - - - 1.1686 0.9996 221125_WJC_METTL3_EV_vs_WT_F02.14913.14913.2 0.00351 20-Sep R.QIPVESVPGIR[166.11].E sp|Q92830|KAT2A_HUMAN 1 1203.6851 1.15 14866 14913 2 1203.685853 602.8498 Histone acetyltransferase KAT2A OS=Homo sapiens OX=9606 GN=KAT2A PE=1 SV=3 6 2928.1 - 1.09E+06 - - - 0.6322 - 1.724 0.388 - 301.9 1 2 0 0.0008 11 0 0 0 3.27E+07 2.85E+07 - - - 3.3799 0.9999 221125_WJC_METTL3_EV_vs_WT_F02.14919.14919.3 3.27E-05 Sep-32 K.YGFYTHVFR.L "sp|P00734|THRB_HUMAN,tr|E9PIT3|E9PIT3_HUMAN" 2 1188.5716 999 14872 14919 3 1188.571282 397.1978 Prothrombin OS=Homo sapiens OX=9606 GN=F2 PE=1 SV=2 8.6 2928.8 - 242999 - - - -0.2919 - 1.872 0.489 - 85 1 2 0 -0.0003 9 0 0 0 5.69E+06 0.00E+00 - - - 5.8814 1 221125_WJC_METTL3_EV_vs_WT_F02.14921.14921.2 1.01E-08 13/24 K.VIDPATATSVDLR[166.11].D sp|P50991|TCPD_HUMAN 1 1366.7332 0.35 14873 14921 2 1366.732421 684.3739 T-complex protein 1 subunit delta OS=Homo sapiens OX=9606 GN=CCT4 PE=1 SV=4 4.21 2929 - 5.91E+06 - - - -0.5444 - 2.628 0.593 - 664.8 1 2 0 -0.0007 13 0 0 0 9.79E+08 2.84E+09 - - - 5.9005 0.9999 221125_WJC_METTL3_EV_vs_WT_F02.14923.14923.2 0.000299 13/22 K.LLLSSETPIEGK.N "sp|Q9HDC9|APMAP_HUMAN,tr|H0Y512|H0Y512_HUMAN" 2 1285.7129 1.17 14874 14923 2 1285.71356 643.8637 Adipocyte plasma membrane-associated protein OS=Homo sapiens OX=9606 GN=APMAP PE=1 SV=2 4.53 2929.3 - 4.52E+06 - - - 0.4877 - 2.534 0.567 - 581.5 1 2 0 0.0006 12 0 0 0 9.96E+07 8.50E+07 - - - 5.6751 0.9998 221125_WJC_METTL3_EV_vs_WT_F02.14924.14924.2 0.111 18-Oct R.IITVSMEDVK.L sp|Q08J23|NSUN2_HUMAN 1 1133.6002 0.06 14875 14924 2 1133.59965 567.8074 RNA cytosine C(5)-methyltransferase NSUN2 OS=Homo sapiens OX=9606 GN=NSUN2 PE=1 SV=2 4.37 2929.3 - 4.73E+06 - - - -0.4949 - 2.172 0.357 - 269.8 1 2 0 -0.0006 10 0 0 0 9.02E+07 1.56E+09 - - - 3.8427 0.9997 221125_WJC_METTL3_EV_vs_WT_F02.14925.14925.3 0.016 13/44 R.ILFR[166.11]PVASQLPR[166.11].L "sp|P35232|PHB_HUMAN,tr|C9JZ20|C9JZ20_HUMAN,tr|E7ESE2|E7ESE2_HUMAN,tr|E9PCW0|E9PCW0_HUMAN,tr|C9JW96|C9JW96_HUMAN" 5 1415.8516 1.18 14876 14925 3 1415.851133 472.9578 Prohibitin OS=Homo sapiens OX=9606 GN=PHB PE=1 SV=1 12 2929.4 - 2.02E+06 - - - -0.3256 - 2.027 0.339 - 263.7 1 2 0 -0.0005 12 0 0 0 2.25E+08 1.91E+08 - - - 4.2779 0.9998 221125_WJC_METTL3_EV_vs_WT_F02.14926.14926.2 0.00196 20-Sep R.QIPVESVPGIR.E sp|Q92830|KAT2A_HUMAN 1 1193.6768 1.15 14877 14926 2 1193.676585 597.8457 Histone acetyltransferase KAT2A OS=Homo sapiens OX=9606 GN=KAT2A PE=1 SV=3 6 2929.5 - 1.54E+06 - - - -0.1985 - 1.784 0.444 - 301.9 1 2 0 -0.0002 11 0 0 0 3.28E+07 2.85E+07 - - - 3.8863 0.9996 221125_WJC_METTL3_EV_vs_WT_F02.14929.14929.3 0.00234 Aug-32 K.FYVHNDIFR.Y "sp|Q13283|G3BP1_HUMAN,tr|A0A7I2V5M7|A0A7I2V5M7_HUMAN,tr|A0A7P0P2U7|A0A7P0P2U7_HUMAN,tr|A0A7I2YQU8|A0A7I2YQU8_HUMAN,tr|A0A7I2V651|A0A7I2V651_HUMAN,tr|A0A7I2YQN9|A0A7I2YQN9_HUMAN,tr|A0A7I2V2V1|A0A7I2V2V1_HUMAN" 7 1209.5931 1.07 14880 14929 3 1209.590913 404.205 Ras GTPase-activating protein-binding protein 1 OS=Homo sapiens OX=9606 GN=G3BP1 PE=1 SV=1 6.74 2929.8 - 482484 - - - -1.8023 - 1.492 0.409 - 71.7 1 2 0 -0.0022 9 0 0 0 2.04E+07 1.91E+07 - - - 4.3052 0.9999 221125_WJC_METTL3_EV_vs_WT_F02.14935.14935.3 0.000122 14/44 R.ILFRPVASQLPR.L "sp|P35232|PHB_HUMAN,tr|C9JZ20|C9JZ20_HUMAN,tr|E7ESE2|E7ESE2_HUMAN,tr|E9PCW0|E9PCW0_HUMAN,tr|C9JW96|C9JW96_HUMAN" 5 1395.8351 1.18 14884 14935 3 1395.836734 466.2856 Prohibitin OS=Homo sapiens OX=9606 GN=PHB PE=1 SV=1 12 2930.5 - 3.88E+06 - - - 1.2036 - 2.317 0.464 - 249.3 1 2 0 0.0017 12 0 0 0 2.25E+08 1.91E+08 - - - 6.0418 0.9998 221125_WJC_METTL3_EV_vs_WT_F02.14937.14937.2 0.000206 18-Nov R.MPGELVLENR[166.11].M "sp|Q71RC2|LARP4_HUMAN,tr|X6RLN4|X6RLN4_HUMAN" 2 1166.5993 1.65 14886 14937 2 1166.59871 584.3069 La-related protein 4 OS=Homo sapiens OX=9606 GN=LARP4 PE=1 SV=3 4.53 2930.6 - 4.64E+06 - - - -0.5177 - 2.244 0.389 - 670.6 1 2 0 -0.0006 10 0 0 0 3.29E+08 1.99E+08 - - - 4.1701 0.9997 221125_WJC_METTL3_EV_vs_WT_F02.14938.14938.2 1.02E-06 18-Nov K.TEVNSGFFYK[136.11].T "sp|Q92526|TCPW_HUMAN,sp|P40227|TCPZ_HUMAN,tr|J3KRI6|J3KRI6_HUMAN" 3 1198.575 0.41 14887 14938 2 1198.577174 600.2948 T-complex protein 1 subunit zeta-2 OS=Homo sapiens OX=9606 GN=CCT6B PE=1 SV=5 5.66 2930.6 - 3.15E+06 - - - 1.823 - 2.297 0.426 - 473 1 2 0 0.0022 10 0 0 0 4.87E+07 1.20E+08 - - - 4.508 1 221125_WJC_METTL3_EV_vs_WT_F02.14940.14940.2 4.21E-12 16/28 R.MGLAMGGGGGASFDR.A "sp|P52272|HNRPM_HUMAN,tr|M0R2I7|M0R2I7_HUMAN,tr|M0QY96|M0QY96_HUMAN,tr|A0A087X0X3|A0A087X0X3_HUMAN" 4 1382.6071 1.67 14889 14940 2 1382.608761 692.3108 Heterogeneous nuclear ribonucleoprotein M OS=Homo sapiens OX=9606 GN=HNRNPM PE=1 SV=3 5.59 2930.9 - 704050 - - - 1.1977 - 2.931 0.665 - 791.6 1 2 0 0.0017 15 0 0 0 2.83E+08 1.69E+08 - - - 6.596 0.9997 221125_WJC_METTL3_EV_vs_WT_F02.14941.14941.2 5.06E-06 18-Dec R.IEYDC[160.03]ELVPR[166.11].R sp|Q9P258|RCC2_HUMAN 1 1302.6154 0.56 14890 14941 2 1302.612568 652.315 Protein RCC2 OS=Homo sapiens OX=9606 GN=RCC2 PE=1 SV=2 4.14 2931 - 692108 - - - -2.1418 - 2.062 0.517 - 375.6 1 2 0 -0.0028 10 0 0 0 2.14E+07 3.81E+07 - - - 4.8787 0.9941 221125_WJC_METTL3_EV_vs_WT_F02.14942.14942.2 0.0101 14-Sep K.SFDTSLIR.K "sp|O75787|RENR_HUMAN,tr|B7Z413|B7Z413_HUMAN,tr|A0A1B0GTU8|A0A1B0GTU8_HUMAN,tr|A0A1B0GVI9|A0A1B0GVI9_HUMAN,tr|B7Z1I9|B7Z1I9_HUMAN,tr|A0A1B0GVC7|A0A1B0GVC7_HUMAN,tr|A0A1B0GUT7|A0A1B0GUT7_HUMAN,tr|A0A1B0GU12|A0A1B0GU12_HUMAN,tr|A0A1B0GUV3|A0A1B0GUV3_HUMAN,tr|A0A1C7CYW4|A0A1C7CYW4_HUMAN,tr|A0A1B0GWD6|A0A1B0GWD6_HUMAN,tr|A0A1B0GVB9|A0A1B0GVB9_HUMAN,tr|A0A1B0GVW0|A0A1B0GVW0_HUMAN" 13 937.4869 1.81 14891 14942 2 937.483671 469.7507 Renin receptor OS=Homo sapiens OX=9606 GN=ATP6AP2 PE=1 SV=2 5.55 2931.1 - 641665 - - - -3.44 - 1.721 0.235 - 249.4 1 2 0 -0.0032 8 0 0 0 4.80E+07 2.66E+07 - - - 2.4131 1 221125_WJC_METTL3_EV_vs_WT_F02.14943.14943.2 1.59E-11 16/28 R.MGLAMGGGGGASFDR[166.11].A "sp|P52272|HNRPM_HUMAN,tr|M0R2I7|M0R2I7_HUMAN,tr|M0QY96|M0QY96_HUMAN,tr|A0A087X0X3|A0A087X0X3_HUMAN" 4 1392.6154 1.66 14892 14943 2 1392.614389 697.315 Heterogeneous nuclear ribonucleoprotein M OS=Homo sapiens OX=9606 GN=HNRNPM PE=1 SV=3 5.59 2931.2 - 517590 - - - -0.708 - 3.06 0.717 - 709.4 1 2 0 -0.001 15 0 0 0 2.81E+08 1.69E+08 - - - 7.0861 0.9994 221125_WJC_METTL3_EV_vs_WT_F02.14945.14945.2 0.0178 22-Jul R.ILFR[166.11]PVASQLPR[166.11].L "sp|P35232|PHB_HUMAN,tr|C9JZ20|C9JZ20_HUMAN,tr|E7ESE2|E7ESE2_HUMAN,tr|E9PCW0|E9PCW0_HUMAN,tr|C9JW96|C9JW96_HUMAN" 5 1415.8516 1.32 14894 14945 2 1415.851177 708.9331 Prohibitin OS=Homo sapiens OX=9606 GN=PHB PE=1 SV=1 12 2931.4 - 186087 - - - -0.2945 - 1.439 0.388 - 49.6 1 2 0 -0.0004 12 0 0 0 1.77E+07 1.34E+07 - - - 2.8642 0.9979 221125_WJC_METTL3_EV_vs_WT_F02.14948.14948.2 0.0432 18-Nov K.LEGLEDALQK.A "sp|P48668|K2C6C_HUMAN,sp|P04259|K2C6B_HUMAN,sp|P02538|K2C6A_HUMAN" 3 1114.587 109.87 14895 14948 2 1114.587397 558.3008 "Keratin, type II cytoskeletal 6C OS=Homo sapiens OX=9606 GN=KRT6C PE=1 SV=3" 4.14 2931.9 - 3.97E+07 - - - 0.3526 - 2.091 0.111 - 325.2 2 2 0 0.0004 10 0 0 0 8.53E+08 7.77E+06 - - - 1.7852 0.9983 221125_WJC_METTL3_EV_vs_WT_F02.14949.14949.2 0.0261 18-Oct K.FIENELEIQK.Q sp|Q7Z353|HDX_HUMAN 1 1261.6554 14 14896 14949 2 1261.65602 631.835 Highly divergent homeobox OS=Homo sapiens OX=9606 GN=HDX PE=1 SV=1 4.25 2931.9 - 2.77E+06 - - - 0.4772 - 1.631 0.214 - 253.4 1 2 0 0.0006 10 0 0 0 5.00E+07 3.57E+06 - - - 1.9869 0.7978 221125_WJC_METTL3_EV_vs_WT_F02.14950.14950.2 2.71 12-Jul S.SSILIIK[136.11].D "sp|Q8WZ42|TITIN_HUMAN,sp|P28066|PSA5_HUMAN,tr|A0A0A0MTS7|A0A0A0MTS7_HUMAN,tr|A0A0A0MRA3|A0A0A0MRA3_HUMAN" 4 780.52 0.74 14897 14950 2 780.520222 391.2673 Titin OS=Homo sapiens OX=9606 GN=TTN PE=1 SV=4 8.47 2932 - 2.19E+06 - - - 0.2319 - 1.496 0.144 - 218.3 2 1 0 0.0002 7 0 0 0 5.54E+07 7.49E+07 - - - 1.2463 0.9978 221125_WJC_METTL3_EV_vs_WT_F02.14952.14952.2 0.0849 14-Jul R.IFSIVEQR[166.11].L "sp|P12081|HARS1_HUMAN,tr|A0A6Q8PF47|A0A6Q8PF47_HUMAN,tr|A0A6Q8PF07|A0A6Q8PF07_HUMAN,tr|B4E1C5|B4E1C5_HUMAN,tr|A0A6Q8PHA5|A0A6Q8PHA5_HUMAN,tr|E7ETE2|E7ETE2_HUMAN,tr|A0A6Q8PFF2|A0A6Q8PFF2_HUMAN,tr|A0A6Q8PHE3|A0A6Q8PHE3_HUMAN,tr|B4DDD8|B4DDD8_HUMAN" 9 1000.5581 0.61 14899 14952 2 1000.558826 501.2863 "Histidine--tRNA ligase, cytoplasmic OS=Homo sapiens OX=9606 GN=HARS1 PE=1 SV=2" 6 2932.1 - 2.01E+06 - - - 0.7246 - 1.706 0.161 - 163.1 1 2 0 0.0007 8 0 0 0 1.91E+07 3.12E+07 - - - 1.8409 0.9993 221125_WJC_METTL3_EV_vs_WT_F02.14954.14954.2 0.00899 18-Jul R.GVFNVQMEPK.V sp|P05198|IF2A_HUMAN 1 1147.5696 0.37 14901 14954 2 1147.569971 574.7921 Eukaryotic translation initiation factor 2 subunit 1 OS=Homo sapiens OX=9606 GN=EIF2S1 PE=1 SV=3 6 2932.3 - 3.07E+06 - - - 0.3407 - 1.583 0.323 - 134.5 1 2 0 0.0004 10 0 0 0 7.56E+07 2.02E+08 - - - 2.7087 0.9858 221125_WJC_METTL3_EV_vs_WT_F02.14956.14956.2 0.101 22-Aug K.NSVPVTVAMVER[166.11].W sp|Q9Y3T9|NOC2L_HUMAN 1 1310.6892 0.15 14903 14956 2 1310.691583 656.3519 Nucleolar complex protein 2 homolog OS=Homo sapiens OX=9606 GN=NOC2L PE=1 SV=4 6 2932.6 - 451741 - - - 1.825 - 1.557 0.091 - 175.3 1 2 0 0.0024 12 0 0 0 7.04E+05 4.71E+06 - - - 0.8774 0.9999 221125_WJC_METTL3_EV_vs_WT_F02.14962.14962.2 0.000528 20-Oct R.LQVVDQPLPVR[166.11].G "sp|P49327|FAS_HUMAN,tr|A0A0U1RQF0|A0A0U1RQF0_HUMAN" 2 1272.7429 0.78 14907 14962 2 1272.743367 637.3787 Fatty acid synthase OS=Homo sapiens OX=9606 GN=FASN PE=1 SV=3 5.84 2933.2 - 4.45E+06 - - - 0.3339 - 2.174 0.494 - 409.5 1 2 0 0.0004 11 0 0 0 1.07E+08 1.37E+08 - - - 4.7904 0.9991 221125_WJC_METTL3_EV_vs_WT_F02.14963.14963.2 0.00164 18-Oct K.TEVNSGFFYK.T "sp|Q92526|TCPW_HUMAN,sp|P40227|TCPZ_HUMAN,tr|J3KRI6|J3KRI6_HUMAN" 3 1190.5608 0.42 14908 14963 2 1190.56444 596.2877 T-complex protein 1 subunit zeta-2 OS=Homo sapiens OX=9606 GN=CCT6B PE=1 SV=5 5.66 2933.2 - 3.15E+06 - - - 3.0666 - 1.953 0.434 - 358.6 1 2 0 0.0037 10 0 0 0 4.75E+07 1.14E+08 - - - 4.1138 0.9988 221125_WJC_METTL3_EV_vs_WT_F02.14964.14964.2 0.97 12-Jun K.LSGFSFK.K sp|P29966|MARCS_HUMAN 1 784.4119 0.66 14909 14964 2 784.412774 393.2132 Myristoylated alanine-rich C-kinase substrate OS=Homo sapiens OX=9606 GN=MARCKS PE=1 SV=4 8.75 2933.3 - 1.56E+06 - - - 1.0632 - 1.444 0.304 - 83.3 1 2 0 0.0008 7 0 0 0 4.19E+07 6.39E+07 - - - 2.4503 0.997 221125_WJC_METTL3_EV_vs_WT_F02.14966.14966.2 0.0308 12-May K.AC[160.03]ELFLR.N sp|Q8IYI6|EXOC8_HUMAN 1 907.4586 1.18 14911 14966 2 907.456744 454.7366 Exocyst complex component 8 OS=Homo sapiens OX=9606 GN=EXOC8 PE=1 SV=2 6.04 2933.5 - 1.67E+06 - - - -2.0155 - 1.209 0.334 - 90.9 1 2 0 -0.0018 7 0 0 0 2.04E+07 1.73E+07 - - - 2.1087 0.9998 221125_WJC_METTL3_EV_vs_WT_F02.14969.14969.2 0.00512 22-Dec K.IIAINSELTQPK[136.11].L "sp|Q8WVX9|FACR1_HUMAN,tr|E9PNW8|E9PNW8_HUMAN" 2 1333.7697 0.79 14914 14969 2 1333.7687 667.8921 Fatty acyl-CoA reductase 1 OS=Homo sapiens OX=9606 GN=FAR1 PE=1 SV=1 6 2933.8 - 813418 - - - -0.725 - 2.304 0.446 - 476.4 1 2 0 -0.001 12 0 0 0 1.28E+07 1.62E+07 - - - 4.5309 0.9998 221125_WJC_METTL3_EV_vs_WT_F02.14970.14970.2 5.09E-06 20-Oct R.LYTQGYISYPR.T "sp|O95985|TOP3B_HUMAN,sp|Q13472|TOP3A_HUMAN,tr|H7C4B0|H7C4B0_HUMAN,tr|H0Y6W0|H0Y6W0_HUMAN" 4 1359.6823 1.24 14915 14970 2 1359.683488 680.8484 DNA topoisomerase 3-beta-1 OS=Homo sapiens OX=9606 GN=TOP3B PE=1 SV=1 8.5 2933.9 - 530272 - - - 0.8723 - 2.102 0.516 - 291.8 1 2 0 0.0012 11 0 0 0 2.02E+07 1.63E+07 - - - 4.8615 0.9935 221125_WJC_METTL3_EV_vs_WT_F02.14974.14974.2 0.0809 12-Jun K.IGLDFC[160.03]K[136.11].Y "sp|O00571|DDX3X_HUMAN,sp|O15523|DDX3Y_HUMAN,tr|A0A2R8YFR4|A0A2R8YFR4_HUMAN,tr|A0A2R8YCW1|A0A2R8YCW1_HUMAN,tr|A0A2R8YDH3|A0A2R8YDH3_HUMAN,tr|A0A2R8YDT5|A0A2R8YDT5_HUMAN,tr|A0A2R8Y645|A0A2R8Y645_HUMAN,tr|A0A2R8YF78|A0A2R8YF78_HUMAN,tr|A0A0D9SFB3|A0A0D9SFB3_HUMAN,tr|A0A2R8YFS5|A0A2R8YFS5_HUMAN,tr|A0A0D9SF53|A0A0D9SF53_HUMAN,tr|A0A2R8Y5G6|A0A2R8Y5G6_HUMAN,tr|A0A2R8Y7T2|A0A2R8Y7T2_HUMAN,tr|A0A0D9SG12|A0A0D9SG12_HUMAN,tr|F6S8Q4|F6S8Q4_HUMAN,tr|A0A2U3TZJ9|A0A2U3TZJ9_HUMAN,tr|A0A2R8Y4A4|A0A2R8Y4A4_HUMAN" 17 859.4353 1.06 14917 14974 2 859.435451 430.7249 ATP-dependent RNA helicase DDX3X OS=Homo sapiens OX=9606 GN=DDX3X PE=1 SV=3 5.83 2934.5 - 7.48E+06 - - - 0.1466 - 1.414 0.107 - 91.1 1 2 0 0.0001 7 0 0 0 1.62E+08 1.53E+08 - - - 0.9289 0.9997 221125_WJC_METTL3_EV_vs_WT_F02.14975.14975.2 0.0173 20-Jul R.LQVVDQPLPVR.G "sp|P49327|FAS_HUMAN,tr|A0A0U1RQF0|A0A0U1RQF0_HUMAN" 2 1262.7347 0.77 14918 14975 2 1262.734609 632.3746 Fatty acid synthase OS=Homo sapiens OX=9606 GN=FASN PE=1 SV=3 5.84 2934.5 - 2.93E+06 - - - -0.0499 - 1.819 0.372 - 183.4 1 2 0 -0.0001 11 0 0 0 1.07E+08 1.38E+08 - - - 3.4071 0.9912 221125_WJC_METTL3_EV_vs_WT_F02.14976.14976.2 0.139 12-Jun K.QEPDPTW.- "sp|P78347|GTF2I_HUMAN,tr|A0A494C1K3|A0A494C1K3_HUMAN" 2 871.3712 - 14919 14976 2 871.371142 436.6929 General transcription factor II-I OS=Homo sapiens OX=9606 GN=GTF2I PE=1 SV=2 3.67 2934.6 - 3.69E+06 - - - -0.0643 - 0.909 0.266 - 83.4 1 2 0 -0.0001 7 0 0 0 - - - - - 0.7033 0.9908 221125_WJC_METTL3_EV_vs_WT_F02.14978.14978.2 0.108 14-Aug K.GVATNWLR.A "sp|P16435|NCPR_HUMAN,tr|H0Y4R2|H0Y4R2_HUMAN,tr|E7EMD0|E7EMD0_HUMAN" 3 915.4927 0.88 14921 14978 2 915.495212 458.7536 NADPH--cytochrome P450 reductase OS=Homo sapiens OX=9606 GN=POR PE=1 SV=2 9.75 2934.7 - 939867 - - - 2.7985 - 1.533 0.182 - 189.1 1 2 0 0.0026 8 0 0 0 3.42E+07 3.90E+07 - - - 1.6729 0.9999 221125_WJC_METTL3_EV_vs_WT_F02.14979.14979.2 1.43E-05 20-Aug R.LYTQGYISYPR[166.11].T "sp|O95985|TOP3B_HUMAN,sp|Q13472|TOP3A_HUMAN,tr|H7C4B0|H7C4B0_HUMAN,tr|H0Y6W0|H0Y6W0_HUMAN" 4 1369.6906 1.24 14922 14979 2 1369.691011 685.8526 DNA topoisomerase 3-beta-1 OS=Homo sapiens OX=9606 GN=TOP3B PE=1 SV=1 8.5 2934.8 - 778220 - - - 0.3205 - 2.133 0.474 - 266.2 1 2 0 0.0004 11 0 0 0 2.02E+07 1.63E+07 - - - 4.5911 0.9997 221125_WJC_METTL3_EV_vs_WT_F02.14983.14983.2 0.0327 12-Jul K.LSGFSFK[136.11].K sp|P29966|MARCS_HUMAN 1 792.4261 0.66 14925 14983 2 792.426166 397.2203 Myristoylated alanine-rich C-kinase substrate OS=Homo sapiens OX=9606 GN=MARCKS PE=1 SV=4 8.75 2935.3 - 4.18E+06 - - - 0.0328 - 1.597 0.39 - 134.9 1 2 0 0 7 0 0 0 4.20E+07 6.39E+07 - - - 3.4048 0.9995 221125_WJC_METTL3_EV_vs_WT_F02.14985.14985.2 0.00217 18-Aug R.DLGFNGAPYR.S sp|Q9Y5B9|SP16H_HUMAN 1 1108.5302 1.08 14926 14985 2 1108.530142 555.2724 FACT complex subunit SPT16 OS=Homo sapiens OX=9606 GN=SUPT16H PE=1 SV=1 5.84 2935.5 - 2.45E+06 - - - -0.0144 - 1.557 0.384 - 219.7 1 2 0 0 10 0 0 0 6.96E+07 6.44E+07 - - - 3.1131 0.9997 221125_WJC_METTL3_EV_vs_WT_F02.14986.14986.2 0.000241 22-Oct R.VIAEGDLGIVEK.T "sp|O95861|BPNT1_HUMAN,tr|F8W1J0|F8W1J0_HUMAN,tr|F8VVW8|F8VVW8_HUMAN,tr|A6NF51|A6NF51_HUMAN,tr|F8VZG4|F8VZG4_HUMAN" 5 1241.6867 1.09 14927 14986 2 1241.689114 621.8506 "3'(2'),5'-bisphosphate nucleotidase 1 OS=Homo sapiens OX=9606 GN=BPNT1 PE=1 SV=1" 4.14 2935.6 - 899731 - - - 1.9296 - 2.188 0.525 - 217.4 1 2 0 0.0024 12 0 0 0 2.52E+07 2.32E+07 - - - 4.9781 0.9646 221125_WJC_METTL3_EV_vs_WT_F02.14988.14988.2 0.0132 14-Aug L.LQDFFNGR[166.11].D "sp|P0DMV8|HS71A_HUMAN,sp|P0DMV9|HS71B_HUMAN,tr|V9GZ37|V9GZ37_HUMAN,tr|A0A0G2JIW1|A0A0G2JIW1_HUMAN" 4 1005.4907 0.14 14929 14988 2 1005.491089 503.7527 Heat shock 70 kDa protein 1A OS=Homo sapiens OX=9606 GN=HSPA1A PE=1 SV=1 5.84 2935.7 - 1.46E+06 - - - 0.3381 - 1.694 0.303 - 198.3 1 1 0 0.0003 8 0 0 0 6.88E+06 4.84E+07 - - - 2.8685 0.9998 221125_WJC_METTL3_EV_vs_WT_F02.14991.14991.2 0.000447 18-Sep R.YDDAIQLYDR[166.11].L "sp|Q15006|EMC2_HUMAN,tr|H0YAS9|H0YAS9_HUMAN" 2 1280.5913 1.54 14932 14991 2 1280.591444 641.3029 ER membrane protein complex subunit 2 OS=Homo sapiens OX=9606 GN=EMC2 PE=1 SV=1 3.93 2936 - 717860 - - - 0.1507 - 1.969 0.463 - 215.3 1 2 0 0.0002 10 0 0 0 3.14E+07 2.04E+07 - - - 4.3518 0.9999 221125_WJC_METTL3_EV_vs_WT_F02.14993.14993.2 0.000158 13/22 K.IIAINSELTQPK.L "sp|Q8WVX9|FACR1_HUMAN,tr|E9PNW8|E9PNW8_HUMAN" 2 1325.7555 0.79 14934 14993 2 1325.755333 663.885 Fatty acyl-CoA reductase 1 OS=Homo sapiens OX=9606 GN=FAR1 PE=1 SV=1 6 2936.2 - 475597 - - - -0.1011 - 2.458 0.46 - 571.8 1 2 0 -0.0001 12 0 0 0 1.28E+07 1.62E+07 - - - 4.8049 0.9988 221125_WJC_METTL3_EV_vs_WT_F02.14997.14997.2 0.131 20-Dec K.LATELPDAELR[166.11].R sp|Q93034|CUL5_HUMAN 1 1236.6589 1.21 14936 14997 2 1236.661176 619.3367 Cullin-5 OS=Homo sapiens OX=9606 GN=CUL5 PE=1 SV=4 4.14 2936.7 - 383501 - - - 1.8105 - 2.032 0.254 - 592.1 1 2 0 0.0022 11 0 0 0 5.78E+06 4.79E+06 - - - 2.8344 0.9818 221125_WJC_METTL3_EV_vs_WT_F02.15002.15002.2 2.29 12-Jul K.SLLTQLR[166.11].A sp|Q96SZ5|AEDO_HUMAN 1 839.5104 0.69 14938 15002 2 839.510309 420.7625 2-aminoethanethiol dioxygenase OS=Homo sapiens OX=9606 GN=ADO PE=1 SV=2 9.47 2937.3 - 465679 - - - -0.1346 - 1.302 0.046 - 185.3 1 2 0 -0.0001 7 0 0 0 4.75E+06 6.91E+06 - - - 0.2169 0.9982 221125_WJC_METTL3_EV_vs_WT_F02.15004.15004.2 0.521 12-Aug K.IEDFLER[166.11].R "sp|P46781|RS9_HUMAN,tr|C9JM19|C9JM19_HUMAN,tr|B5MCT8|B5MCT8_HUMAN" 3 930.4686 1.1 14939 15004 2 930.469234 466.2416 40S ribosomal protein S9 OS=Homo sapiens OX=9606 GN=RPS9 PE=1 SV=3 4.14 2937.5 - 2.32E+07 - - - 0.6631 - 1.713 0.169 - 186.4 1 2 0 0.0006 7 0 0 0 4.60E+08 4.17E+08 - - - 1.9945 0.9998 221125_WJC_METTL3_EV_vs_WT_F02.15005.15005.2 9.43E-06 20-Nov R.VTYVVLDEADR[166.11].M "sp|Q7L014|DDX46_HUMAN,tr|A0A0C4DG89|A0A0C4DG89_HUMAN" 2 1288.6539 1.51 14940 15005 2 1288.656348 645.3342 Probable ATP-dependent RNA helicase DDX46 OS=Homo sapiens OX=9606 GN=DDX46 PE=1 SV=2 4.03 2937.7 - 611055 - - - 1.9369 - 2.195 0.557 - 403.6 1 2 0 0.0025 11 0 0 0 2.27E+07 1.50E+07 - - - 5.281 0.9227 221125_WJC_METTL3_EV_vs_WT_F02.15008.15008.2 0.0123 16-Aug K.YTGVLTELK[136.11].L sp|P23378|GCSP_HUMAN 1 1030.579 0.15 14943 15008 2 1030.58616 516.2968 "Glycine dehydrogenase (decarboxylating), mitochondrial OS=Homo sapiens OX=9606 GN=GLDC PE=1 SV=2" 6 2938 - 398799 - - - 6.9359 - 1.621 0.237 - 162.3 1 2 0 0.0071 9 0 0 0 2.26E+06 1.47E+07 - - - 2.1867 0.9995 221125_WJC_METTL3_EV_vs_WT_F02.15013.15013.2 0.0247 16-Oct K.VPEWVDTVK[136.11].L "sp|P39019|RS19_HUMAN,tr|M0R140|M0R140_HUMAN,tr|M0R2L9|M0R2L9_HUMAN,tr|M0QYF7|M0QYF7_HUMAN" 4 1079.5743 1.12 14946 15013 2 1079.574735 540.7944 40S ribosomal protein S19 OS=Homo sapiens OX=9606 GN=RPS19 PE=1 SV=2 4.37 2938.6 - 1.17E+07 - - - 0.4391 - 1.795 0.318 - 367.2 1 2 0 0.0005 9 0 0 0 3.23E+09 2.87E+09 - - - 3.082 0.9997 221125_WJC_METTL3_EV_vs_WT_F02.15014.15014.2 5.73E-05 16-Oct K.VPEWVDTVK.L "sp|P39019|RS19_HUMAN,tr|M0R140|M0R140_HUMAN,tr|M0R2L9|M0R2L9_HUMAN,tr|M0QYF7|M0QYF7_HUMAN" 4 1071.5601 1.12 14947 15014 2 1071.558631 536.7873 40S ribosomal protein S19 OS=Homo sapiens OX=9606 GN=RPS19 PE=1 SV=2 4.37 2938.7 - 8.89E+06 - - - -1.3345 - 1.779 0.454 - 328.8 1 2 0 -0.0014 9 0 0 0 3.23E+09 2.87E+09 - - - 4.0603 0.9998 221125_WJC_METTL3_EV_vs_WT_F02.15015.15015.2 0.00375 14-Sep K.YYYIPQYK.N "sp|Q8N183|NDUF2_HUMAN,tr|H0YA50|H0YA50_HUMAN,tr|A0A7I2V3X5|A0A7I2V3X5_HUMAN,tr|D6RA56|D6RA56_HUMAN,tr|A0A7I2YQX2|A0A7I2YQX2_HUMAN,tr|A0A7I2V4Z7|A0A7I2V4Z7_HUMAN" 6 1136.5542 1.74 14948 15015 2 1136.55297 569.2844 NADH dehydrogenase [ubiquinone] 1 alpha subcomplex assembly factor 2 OS=Homo sapiens OX=9606 GN=NDUFAF2 PE=1 SV=1 8.38 2938.7 - 3.50E+06 - - - -1.1236 - 1.911 0.504 - 223.3 1 2 0 -0.0013 8 0 0 0 1.63E+08 9.35E+07 - - - 4.7164 0.9997 221125_WJC_METTL3_EV_vs_WT_F02.15016.15016.2 0.0436 13/20 K.LAADAGTFLSR.A "sp|Q9Y371|SHLB1_HUMAN,tr|A0A087WW40|A0A087WW40_HUMAN" 2 1120.5877 0.64 14949 15016 2 1120.586798 561.3011 Endophilin-B1 OS=Homo sapiens OX=9606 GN=SH3GLB1 PE=1 SV=1 5.84 2938.8 - 3.35E+06 - - - -0.7808 - 2.658 0.276 - 594.9 1 2 0 -0.0009 11 0 0 0 8.52E+07 1.34E+08 - - - 3.7238 0.9971 221125_WJC_METTL3_EV_vs_WT_F02.15019.15019.2 0.0922 14-Jul K.DYVILATR.T sp|Q5SWX8|ODR4_HUMAN 1 949.5233 1.29 14952 15019 2 949.524153 475.7689 Protein odr-4 homolog OS=Homo sapiens OX=9606 GN=ODR4 PE=1 SV=1 5.84 2938.9 - 1.54E+06 - - - 0.9173 - 1.41 0.22 - 201.8 1 2 0 0.0009 8 0 0 0 4.38E+07 3.41E+07 - - - 1.7019 0.8245 221125_WJC_METTL3_EV_vs_WT_F02.15024.15024.2 0.0679 14-Jul G.LALTLQPR.G sp|P03971|MIS_HUMAN 1 910.56 1.56 14957 15024 2 910.558929 456.2873 Muellerian-inhibiting factor OS=Homo sapiens OX=9606 GN=AMH PE=1 SV=3 9.75 2939.5 - 451885 - - - -1.1784 - 1.392 0.205 - 109.8 1 1 0 -0.0011 8 0 0 0 1.21E+07 7.75E+06 - - - 1.5523 0.9993 221125_WJC_METTL3_EV_vs_WT_F02.15030.15030.2 0.0043 18-Sep K.AISSDMYFGR[166.11].Q "sp|Q9NP61|ARFG3_HUMAN,tr|H0Y6A0|H0Y6A0_HUMAN" 2 1155.5258 0.93 14961 15030 2 1155.525325 578.7702 ADP-ribosylation factor GTPase-activating protein 3 OS=Homo sapiens OX=9606 GN=ARFGAP3 PE=1 SV=1 5.88 2940.3 - 6.13E+06 - - - -0.4232 - 1.55 0.338 - 235.5 1 2 0 -0.0005 10 0 0 0 1.35E+08 1.45E+08 - - - 2.7606 0.9983 221125_WJC_METTL3_EV_vs_WT_F02.15031.15031.2 0.0228 18-Aug K.AISSDMYFGR.Q "sp|Q9NP61|ARFG3_HUMAN,tr|H0Y6A0|H0Y6A0_HUMAN" 2 1145.5175 0.94 14962 15031 2 1145.517049 573.766 ADP-ribosylation factor GTPase-activating protein 3 OS=Homo sapiens OX=9606 GN=ARFGAP3 PE=1 SV=1 5.88 2940.3 - 6.02E+06 - - - -0.4321 - 1.279 0.298 - 152.1 1 2 0 -0.0005 10 0 0 0 1.35E+08 1.43E+08 - - - 1.9288 0.9998 221125_WJC_METTL3_EV_vs_WT_F02.15032.15032.2 0.00101 16-Aug K.FVMQEEFSR[166.11].D sp|P30101|PDIA3_HUMAN 1 1181.5415 0.63 14963 15032 2 1181.541307 591.778 Protein disulfide-isomerase A3 OS=Homo sapiens OX=9606 GN=PDIA3 PE=1 SV=4 4.53 2940.4 - 2.90E+06 - - - -0.1329 - 1.577 0.506 - 242.9 1 2 0 -0.0002 9 0 0 0 2.84E+07 4.49E+07 - - - 4.0961 0.9998 221125_WJC_METTL3_EV_vs_WT_F02.15040.15040.2 0.00207 16-Sep R.VIAC[160.03]FDSLK.G "sp|Q9NR56|MBNL1_HUMAN,sp|Q5VZF2|MBNL2_HUMAN,tr|H7C4T5|H7C4T5_HUMAN,tr|A0A0A0MQX8|A0A0A0MQX8_HUMAN,tr|A0A7P0T9I3|A0A7P0T9I3_HUMAN,tr|C9JP00|C9JP00_HUMAN,tr|O95205|O95205_HUMAN" 7 1051.5372 1.31 14970 15040 2 1051.538636 526.7759 Muscleblind-like protein 1 OS=Homo sapiens OX=9606 GN=MBNL1 PE=1 SV=2 5.8 2941.2 - 2.12E+07 - - - 1.3495 - 1.793 0.526 - 269.3 1 2 0 0.0014 9 0 0 0 4.74E+08 3.63E+08 - - - 4.6148 0.9804 221125_WJC_METTL3_EV_vs_WT_F02.15042.15042.2 0.0549 16-Sep N.ILLQIDNAR.L "sp|Q04695|K1C17_HUMAN,sp|Q99456|K1C12_HUMAN,sp|P13645|K1C10_HUMAN,tr|K7EPJ9|K7EPJ9_HUMAN,tr|A0A1B0GVI3|A0A1B0GVI3_HUMAN,tr|F5GWP8|F5GWP8_HUMAN,tr|A0A3B3ITG2|A0A3B3ITG2_HUMAN" 7 1054.6135 999 14971 15042 2 1054.613682 528.314 "Keratin, type I cytoskeletal 17 OS=Homo sapiens OX=9606 GN=KRT17 PE=1 SV=2" 5.84 2941.4 - 1.65E+07 - - - 0.1783 - 1.945 0.34 - 265.7 1 1 0 0.0002 9 0 0 0 3.62E+08 0.00E+00 - - - 3.4768 0.9985 221125_WJC_METTL3_EV_vs_WT_F02.15044.15044.2 0.0114 14-Jul K.DYVILATR[166.11].T sp|Q5SWX8|ODR4_HUMAN 1 959.5316 1.31 14973 15044 2 959.531641 480.7731 Protein odr-4 homolog OS=Homo sapiens OX=9606 GN=ODR4 PE=1 SV=1 5.84 2941.5 - 1.81E+06 - - - 0.0928 - 1.55 0.226 - 193.1 1 2 0 0.0001 8 0 0 0 4.46E+07 3.41E+07 - - - 2.032 0.9997 221125_WJC_METTL3_EV_vs_WT_F02.15045.15045.2 0.000756 18-Nov K.YSQLVVETIR.R sp|Q92522|H1X_HUMAN 1 1206.6608 1.57 14974 15045 2 1206.663231 604.3377 Histone H1.10 OS=Homo sapiens OX=9606 GN=H1-10 PE=1 SV=1 6 2941.6 - 1.14E+06 - - - 1.9832 - 2.295 0.467 - 384 1 2 0 0.0024 10 0 0 0 3.85E+07 2.45E+07 - - - 4.8083 1 221125_WJC_METTL3_EV_vs_WT_F02.15046.15046.2 0.000674 18-Nov K.FFGYC[160.03]NDVDR.E "sp|Q9NRP2|COXM2_HUMAN,tr|H3BNN8|H3BNN8_HUMAN,tr|H3BQQ1|H3BQQ1_HUMAN,tr|H3BTB6|H3BTB6_HUMAN" 4 1291.5292 1.62 14975 15046 2 1291.52948 646.7719 COX assembly mitochondrial protein 2 homolog OS=Homo sapiens OX=9606 GN=CMC2 PE=1 SV=1 4.21 2941.8 - 864158 - - - 0.2385 - 2.036 0.663 - 351 1 2 0 0.0003 10 0 0 0 3.45E+07 2.14E+07 - - - 5.9224 0.9999 221125_WJC_METTL3_EV_vs_WT_F02.15047.15047.2 9.54E-05 18-Nov K.FFGYC[160.03]NDVDR[166.11].E "sp|Q9NRP2|COXM2_HUMAN,tr|H3BNN8|H3BNN8_HUMAN,tr|H3BQQ1|H3BQQ1_HUMAN,tr|H3BTB6|H3BTB6_HUMAN" 4 1301.5374 1.63 14976 15047 2 1301.538099 651.776 COX assembly mitochondrial protein 2 homolog OS=Homo sapiens OX=9606 GN=CMC2 PE=1 SV=1 4.21 2941.9 - 727828 - - - 0.5048 - 2.188 0.601 - 284.5 1 2 0 0.0007 10 0 0 0 3.45E+07 2.12E+07 - - - 5.6653 0.8519 221125_WJC_METTL3_EV_vs_WT_F02.15054.15054.2 0.112 20-Sep R.AAYFGVYDTAK[136.11].G "sp|P12235|ADT1_HUMAN,sp|P12236|ADT3_HUMAN,tr|V9GYG0|V9GYG0_HUMAN" 3 1212.5906 0.53 14981 15054 2 1212.596238 607.3026 ADP\ATP translocase 1 OS=Homo sapiens OX=9606 GN=SLC25A4 PE=1 SV=4 5.88 2942.8 - 3.58E+06 - - - 4.6166 - 1.406 0.077 - 142 1 2 0 0.0056 11 0 0 0 4.18E+07 7.86E+07 - - - 0.5298 0.999 221125_WJC_METTL3_EV_vs_WT_F02.15055.15055.2 0.00322 16-Nov R.LADALQELR.A "sp|P02545|LMNA_HUMAN,tr|A0A6Q8PF80|A0A6Q8PF80_HUMAN,tr|A0A804HL68|A0A804HL68_HUMAN,tr|Q5TCI8|Q5TCI8_HUMAN,tr|A0A6Q8PFJ0|A0A6Q8PFJ0_HUMAN,tr|A0A6Q8PHQ9|A0A6Q8PHQ9_HUMAN,tr|Q3BDU5|Q3BDU5_HUMAN" 7 1027.5662 1.65 14982 15055 2 1027.563154 514.7904 Prelamin-A\C OS=Homo sapiens OX=9606 GN=LMNA PE=1 SV=1 4.37 2942.9 - 1.91E+06 - - - -2.973 - 2.396 0.313 - 410.2 1 2 0 -0.0031 9 0 0 0 8.39E+07 5.08E+07 - - - 3.8798 0.9968 221125_WJC_METTL3_EV_vs_WT_F02.15056.15056.2 1.22 14-Jul K.LALDYGIK.F "sp|P61006|RAB8A_HUMAN,sp|Q92930|RAB8B_HUMAN,tr|H0YNE9|H0YNE9_HUMAN" 3 891.5066 0.94 14983 15056 2 891.506278 446.7606 Ras-related protein Rab-8A OS=Homo sapiens OX=9606 GN=RAB8A PE=1 SV=1 5.83 2942.9 - 1.65E+06 - - - -0.3264 - 1.406 0.214 - 108.5 3 2 0 -0.0003 8 0 0 0 2.04E+07 2.16E+07 - - - 1.4361 0.9975 221125_WJC_METTL3_EV_vs_WT_F02.15068.15068.2 0.0295 12-Jul R.IDDIFER.S "sp|Q01082|SPTB2_HUMAN,tr|A0A087WUZ3|A0A087WUZ3_HUMAN" 2 906.4447 3.56 14993 15068 2 906.442008 454.2296 "Spectrin beta chain, non-erythrocytic 1 OS=Homo sapiens OX=9606 GN=SPTBN1 PE=1 SV=2" 4.03 2944 - 1.16E+06 - - - -2.9665 - 1.667 0.3 - 138.3 1 2 0 -0.0027 7 0 0 0 1.03E+08 2.90E+07 - - - 2.8752 0.9589 221125_WJC_METTL3_EV_vs_WT_F02.15069.15069.2 8.05 14-Jun R.VQLETIIK.S "sp|Q9UBC2|EP15R_HUMAN,tr|M0R2S2|M0R2S2_HUMAN,tr|M0R165|M0R165_HUMAN" 3 942.575 1.54 14994 15069 2 942.57413 472.2948 Epidermal growth factor receptor substrate 15-like 1 OS=Homo sapiens OX=9606 GN=EPS15L1 PE=1 SV=1 5.97 2944.1 - 483000 - - - -0.905 - 1.13 0.05 - 92.7 1 2 0 -0.0009 8 0 0 0 7.46E+06 4.84E+06 - - - -0.2214 0.9986 221125_WJC_METTL3_EV_vs_WT_F02.15070.15070.2 0.00358 20-Oct R.LTNLQEGIIPK.K "sp|Q9H0E3|SP130_HUMAN,tr|A0A2R8YDB8|A0A2R8YDB8_HUMAN,tr|H7BXF5|H7BXF5_HUMAN" 3 1224.7078 0.99 14995 15070 2 1224.704905 613.3612 Histone deacetylase complex subunit SAP130 OS=Homo sapiens OX=9606 GN=SAP130 PE=1 SV=1 6 2944.2 - 479357 - - - -2.354 - 2.122 0.264 - 254.8 1 2 0 -0.0029 11 0 0 0 3.14E+07 3.18E+07 - - - 3.0253 0.9995 221125_WJC_METTL3_EV_vs_WT_F02.15076.15076.2 0.00812 16-Sep K.FITPEDLSK[136.11].L "sp|O95757|HS74L_HUMAN,tr|E9PDE8|E9PDE8_HUMAN" 2 1056.5583 0.27 15000 15076 2 1056.55836 529.2864 Heat shock 70 kDa protein 4L OS=Homo sapiens OX=9606 GN=HSPA4L PE=1 SV=3 4.37 2944.8 - 8.89E+06 - - - 0.0786 - 1.595 0.362 - 216.9 1 2 0 0.0001 9 0 0 0 6.28E+07 2.34E+08 - - - 3.0654 0.9744 221125_WJC_METTL3_EV_vs_WT_F02.15080.15080.2 0.0234 14-Sep V.PEWVDTVK[136.11].L "sp|P39019|RS19_HUMAN,tr|M0R140|M0R140_HUMAN,tr|M0R2L9|M0R2L9_HUMAN,tr|M0QYF7|M0QYF7_HUMAN" 4 980.5058 1.22 15004 15080 2 980.506167 491.2602 40S ribosomal protein S19 OS=Homo sapiens OX=9606 GN=RPS19 PE=1 SV=2 4.37 2945.1 - 936895 - - - 0.3264 - 1.96 0.289 - 235.2 1 1 0 0.0003 8 0 0 0 2.90E+07 2.39E+07 - - - 3.205 0.9999 221125_WJC_METTL3_EV_vs_WT_F02.15082.15082.2 0.000141 18-Oct K.LLC[160.03]SNSAFLR.V "sp|Q13564|ULA1_HUMAN,tr|J3KTE3|J3KTE3_HUMAN" 2 1179.607 0.62 15006 15082 2 1179.60768 590.8108 NEDD8-activating enzyme E1 regulatory subunit OS=Homo sapiens OX=9606 GN=NAE1 PE=1 SV=1 8.25 2945.4 - 716619 - - - 0.5527 - 2.215 0.534 - 270.6 1 2 0 0.0007 10 0 0 0 1.18E+07 1.89E+07 - - - 5.2047 0.9984 221125_WJC_METTL3_EV_vs_WT_F02.15086.15086.2 1.65 16-Dec R.LADALQELR[166.11].A "sp|P02545|LMNA_HUMAN,tr|A0A6Q8PF80|A0A6Q8PF80_HUMAN,tr|A0A804HL68|A0A804HL68_HUMAN,tr|Q5TCI8|Q5TCI8_HUMAN,tr|A0A6Q8PFJ0|A0A6Q8PFJ0_HUMAN,tr|A0A6Q8PHQ9|A0A6Q8PHQ9_HUMAN,tr|Q3BDU5|Q3BDU5_HUMAN" 7 1037.5745 1.65 15008 15086 2 1037.574107 519.7945 Prelamin-A\C OS=Homo sapiens OX=9606 GN=LMNA PE=1 SV=1 4.37 2945.9 - 2.82E+06 - - - -0.3585 - 2.308 0.071 - 582.6 1 2 0 -0.0004 9 0 0 0 8.39E+07 5.08E+07 - - - 1.985 0.9998 221125_WJC_METTL3_EV_vs_WT_F02.15087.15087.2 0.00019 14/20 K.VAAAVPVIISR.A "sp|Q14919|NC2A_HUMAN,tr|E9PNC7|E9PNC7_HUMAN,tr|C9JCC6|C9JCC6_HUMAN,tr|E9PQX9|E9PQX9_HUMAN" 4 1094.6812 1.35 15009 15087 2 1094.679645 548.3479 Dr1-associated corepressor OS=Homo sapiens OX=9606 GN=DRAP1 PE=1 SV=3 9.72 2946 - 2.17E+06 - - - -1.4013 - 2.531 0.449 - 731.6 1 2 0 -0.0015 11 0 0 0 5.76E+07 4.26E+07 - - - 4.869 0.9998 221125_WJC_METTL3_EV_vs_WT_F02.15088.15088.2 3.28E-06 20-Nov R.AAYFGVYDTAK.G "sp|P12235|ADT1_HUMAN,sp|P12236|ADT3_HUMAN,tr|V9GYG0|V9GYG0_HUMAN" 3 1204.5764 0.53 15010 15088 2 1204.575193 603.2955 ADP\ATP translocase 1 OS=Homo sapiens OX=9606 GN=SLC25A4 PE=1 SV=4 5.88 2946.1 - 2.71E+06 - - - -1.0352 - 1.883 0.531 - 251.6 1 2 0 -0.0012 11 0 0 0 4.18E+07 7.86E+07 - - - 4.6746 0.9998 221125_WJC_METTL3_EV_vs_WT_F02.15089.15089.2 0.0001 13/20 K.VAAAVPVIISR[166.11].A "sp|Q14919|NC2A_HUMAN,tr|E9PNC7|E9PNC7_HUMAN,tr|C9JCC6|C9JCC6_HUMAN,tr|E9PQX9|E9PQX9_HUMAN" 4 1104.6894 1.35 15011 15089 2 1104.688296 553.352 Dr1-associated corepressor OS=Homo sapiens OX=9606 GN=DRAP1 PE=1 SV=3 9.72 2946.1 - 1.68E+06 - - - -1.0437 - 2.567 0.401 - 584.9 1 2 0 -0.0012 11 0 0 0 5.76E+07 4.26E+07 - - - 4.5528 0.9891 221125_WJC_METTL3_EV_vs_WT_F02.15090.15090.2 0.00972 12-Sep K.VSQWWER[166.11].L "sp|Q9P035|HACD3_HUMAN,tr|H3BPZ1|H3BPZ1_HUMAN,tr|H3BS72|H3BS72_HUMAN" 3 999.4802 0.94 15012 15090 2 999.47526 500.7474 Very-long-chain (3R)-3-hydroxyacyl-CoA dehydratase 3 OS=Homo sapiens OX=9606 GN=HACD3 PE=1 SV=2 5.97 2946.2 - 1.07E+06 - - - -4.9276 - 1.868 0.246 - 375.3 1 2 0 -0.0049 7 0 0 0 3.23E+07 3.42E+07 - - - 2.8363 0.9908 221125_WJC_METTL3_EV_vs_WT_F02.15091.15091.2 0.0296 14-Jun R.EELVDALR.A "sp|Q6P087|RUSD3_HUMAN,tr|H7C1H7|H7C1H7_HUMAN,tr|H7C454|H7C454_HUMAN,tr|C9JM75|C9JM75_HUMAN,tr|H7C0K7|H7C0K7_HUMAN" 5 943.4975 2.34 15013 15091 2 943.494161 472.756 Mitochondrial mRNA pseudouridine synthase RPUSD3 OS=Homo sapiens OX=9606 GN=RPUSD3 PE=1 SV=3 4.14 2946.3 - 687932 - - - -3.4976 - 1.556 0.228 - 103.9 1 2 0 -0.0033 8 0 0 0 1.05E+07 4.50E+06 - - - 2.0574 0.9884 221125_WJC_METTL3_EV_vs_WT_F02.15092.15092.2 0.228 12-May R.GNFLEIK[136.11].N "sp|Q14839|CHD4_HUMAN,tr|A0A2R8Y4X2|A0A2R8Y4X2_HUMAN,tr|A0A2U3TZM0|A0A2U3TZM0_HUMAN,tr|A0A2R8YD40|A0A2R8YD40_HUMAN,tr|A0A2R8Y5J0|A0A2R8Y5J0_HUMAN,tr|A0A2R8Y425|A0A2R8Y425_HUMAN,tr|A0A2R8YFK9|A0A2R8YFK9_HUMAN,tr|A0A0C4DGG9|A0A0C4DGG9_HUMAN,tr|A0A2R8YFD8|A0A2R8YFD8_HUMAN,tr|A0A2R8YDW2|A0A2R8YDW2_HUMAN,tr|A0A2R8Y7I0|A0A2R8Y7I0_HUMAN,tr|F5GWX5|F5GWX5_HUMAN,tr|A0A2R8Y7M9|A0A2R8Y7M9_HUMAN,tr|A0A2R8Y521|A0A2R8Y521_HUMAN,tr|A0A2R8YDJ9|A0A2R8YDJ9_HUMAN,tr|A0A2R8Y212|A0A2R8Y212_HUMAN" 16 827.4633 0.84 15014 15092 2 827.462275 414.7389 Chromodomain-helicase-DNA-binding protein 4 OS=Homo sapiens OX=9606 GN=CHD4 PE=1 SV=2 6 2946.5 - 526482 - - - -1.1831 - 1.271 0.158 - 115.3 4 2 0 -0.001 7 0 0 0 4.41E+07 5.26E+07 - - - 0.6986 0.9996 221125_WJC_METTL3_EV_vs_WT_F02.15097.15097.2 0.0309 18-Aug R.YPVNSVNILK.A "sp|P17987|TCPA_HUMAN,tr|E7EQR6|E7EQR6_HUMAN,tr|E7ERF2|E7ERF2_HUMAN" 3 1145.6445 0.48 15017 15097 2 1145.644098 573.8295 T-complex protein 1 subunit alpha OS=Homo sapiens OX=9606 GN=TCP1 PE=1 SV=1 8.59 2947.1 - 1.04E+07 - - - -0.3151 - 1.807 0.345 - 157.9 1 2 0 -0.0004 10 0 0 0 1.53E+09 3.17E+09 - - - 3.2406 0.9922 221125_WJC_METTL3_EV_vs_WT_F02.15098.15098.2 1.91 14-Jun K.K[136.11]FQEAVEK[136.11].V "sp|Q9UKM7|MA1B1_HUMAN,tr|H0YG20|H0YG20_HUMAN,tr|A0A804HKS1|A0A804HKS1_HUMAN,tr|H0YGV7|H0YGV7_HUMAN,tr|A0A804HL65|A0A804HL65_HUMAN,tr|A0A804HK01|A0A804HK01_HUMAN,tr|A0A804HJ23|A0A804HJ23_HUMAN,tr|A0A804HHU1|A0A804HHU1_HUMAN,tr|A0A804HK86|A0A804HK86_HUMAN,tr|A0A804HJ66|A0A804HJ66_HUMAN,tr|H0YGQ1|H0YGQ1_HUMAN,tr|H0YI64|H0YI64_HUMAN" 12 993.5466 0.13 15018 15098 2 993.547383 497.7806 "Endoplasmic reticulum mannosyl-oligosaccharide 1,2-alpha-mannosidase OS=Homo sapiens OX=9606 GN=MAN1B1 PE=1 SV=2" 6.14 2947.2 - 2.80E+06 - - - 0.7921 - 1.295 0.149 - 133.4 1 2 0 0.0008 8 0 0 0 7.88E+06 5.96E+07 - - - 0.9209 0.9998 221125_WJC_METTL3_EV_vs_WT_F02.15099.15099.2 4.28E-05 18-Oct R.LDQTMGLSIR.T sp|Q9Y6D9|MD1L1_HUMAN 1 1132.591 2.1 15019 15099 2 1132.591599 567.3028 Mitotic spindle assembly checkpoint protein MAD1 OS=Homo sapiens OX=9606 GN=MAD1L1 PE=1 SV=2 5.84 2947.2 - 3.87E+06 - - - 0.49 - 2.323 0.429 - 371.7 1 2 0 0.0006 10 0 0 0 5.92E+07 2.82E+07 - - - 4.5621 0.9996 221125_WJC_METTL3_EV_vs_WT_F02.15100.15100.2 0.000162 18-Jul K.LVSQIEDAMR.K "sp|Q96RN5|MED15_HUMAN,tr|F8WDM6|F8WDM6_HUMAN,tr|F2Z2B7|F2Z2B7_HUMAN" 3 1160.586 4.49 15020 15100 2 1160.588281 581.3003 Mediator of RNA polymerase II transcription subunit 15 OS=Homo sapiens OX=9606 GN=MED15 PE=1 SV=2 4.37 2947.3 - 2.67E+06 - - - 2.0016 - 1.751 0.498 - 130.5 1 2 0 0.0023 10 0 0 0 5.11E+07 1.14E+07 - - - 4.2822 0.8615 221125_WJC_METTL3_EV_vs_WT_F02.15101.15101.2 3.68 12-Apr R.NLVSYLK.Q "sp|Q96T37|RBM15_HUMAN,sp|Q8NDT2|RB15B_HUMAN,tr|A0A494C001|A0A494C001_HUMAN,tr|A0A499FJY3|A0A499FJY3_HUMAN,tr|A0A087WWP4|A0A087WWP4_HUMAN" 5 835.4804 0.9 15021 15101 2 835.479309 418.7475 RNA-binding protein 15 OS=Homo sapiens OX=9606 GN=RBM15 PE=1 SV=2 8.59 2947.3 - 2.04E+06 - - - -1.2508 - 0.965 0.065 - 61.7 6 2 0 -0.001 7 0 0 0 3.40E+07 3.79E+07 - - - -0.9397 0.9983 221125_WJC_METTL3_EV_vs_WT_F02.15103.15103.2 0.00838 22-Oct K.AAYAGGLVLDPK[136.11].V "sp|P09884|DPOLA_HUMAN,tr|A6NMQ1|A6NMQ1_HUMAN" 2 1181.6536 0.56 15023 15103 2 1181.656778 591.8341 DNA polymerase alpha catalytic subunit OS=Homo sapiens OX=9606 GN=POLA1 PE=1 SV=2 5.88 2947.5 - 465489 - - - 2.7115 - 1.524 0.404 - 206.4 1 2 0 0.0032 12 0 0 0 3.43E+06 6.08E+06 - - - 3.1326 0.9869 221125_WJC_METTL3_EV_vs_WT_F02.15105.15105.2 0.152 12-Jul R.NLVSYLK[136.11].Q "sp|Q96T37|RBM15_HUMAN,sp|Q8NDT2|RB15B_HUMAN,tr|A0A494C001|A0A494C001_HUMAN,tr|A0A499FJY3|A0A499FJY3_HUMAN,tr|A0A087WWP4|A0A087WWP4_HUMAN" 5 843.4946 1.28 15024 15105 2 843.493091 422.7546 RNA-binding protein 15 OS=Homo sapiens OX=9606 GN=RBM15 PE=1 SV=2 8.59 2947.7 - 2.45E+06 - - - -1.7345 - 1.369 0.108 - 212.8 1 2 0 -0.0015 7 0 0 0 5.55E+07 4.33E+07 - - - 0.8334 0.9999 221125_WJC_METTL3_EV_vs_WT_F02.15107.15107.2 1.59E-05 18-Oct K.MFLYADNEDR.A "sp|Q9NP79|VTA1_HUMAN,tr|Q5TGM0|Q5TGM0_HUMAN,tr|A0A087WY55|A0A087WY55_HUMAN" 3 1272.5445 1.58 15025 15107 2 1272.54463 637.2795 Vacuolar protein sorting-associated protein VTA1 homolog OS=Homo sapiens OX=9606 GN=VTA1 PE=1 SV=1 4.03 2947.9 - 2.68E+06 - - - 0.1124 - 2.184 0.594 - 414.9 1 2 0 0.0001 10 0 0 0 1.82E+08 1.15E+08 - - - 5.6087 0.9987 221125_WJC_METTL3_EV_vs_WT_F02.15108.15108.2 0.065 16-Jun R.LEVNLQAMK[136.11].A sp|P35579|MYH9_HUMAN 1 1052.578 0.17 15026 15108 2 1052.578687 527.2963 Myosin-9 OS=Homo sapiens OX=9606 GN=MYH9 PE=1 SV=4 6 2948 - 1.54E+06 - - - 0.685 - 1.655 0.236 - 85.1 1 2 0 0.0007 9 0 0 0 4.10E+06 2.47E+07 - - - 2.2414 0.9993 221125_WJC_METTL3_EV_vs_WT_F02.15111.15111.2 0.0258 12-Aug R.SQQWLLR[166.11].N "sp|Q10472|GALT1_HUMAN,sp|Q8IUC8|GLT13_HUMAN,tr|H7C2I5|H7C2I5_HUMAN" 3 939.5166 1.11 15029 15111 2 939.516041 470.7656 Polypeptide N-acetylgalactosaminyltransferase 1 OS=Homo sapiens OX=9606 GN=GALNT1 PE=1 SV=1 9.47 2948.2 - 1.51E+06 - - - -0.5631 - 1.698 0.276 - 405.8 1 2 0 -0.0005 7 0 0 0 9.51E+07 8.55E+07 - - - 2.757 0.9986 221125_WJC_METTL3_EV_vs_WT_F02.15112.15112.2 0.153 16-Aug K.FITPEDLSK.L "sp|O95757|HS74L_HUMAN,tr|E9PDE8|E9PDE8_HUMAN" 2 1048.5441 0.19 15030 15112 2 1048.542699 525.2793 Heat shock 70 kDa protein 4L OS=Homo sapiens OX=9606 GN=HSPA4L PE=1 SV=3 4.37 2948.4 - 1.02E+06 - - - -1.3142 - 1.388 0.325 - 171.1 1 2 0 -0.0014 9 0 0 0 3.31E+07 1.76E+08 - - - 2.3895 0.9998 221125_WJC_METTL3_EV_vs_WT_F02.15117.15117.2 1.45E-07 26-Nov R.LYPAVDEQETPLPR.S sp|Q96S59|RANB9_HUMAN 1 1626.8253 3.05 15035 15117 2 1626.822504 814.4199 Ran-binding protein 9 OS=Homo sapiens OX=9606 GN=RANBP9 PE=1 SV=1 4.14 2949 - 348240 - - - -1.7414 - 2.354 0.576 - 382.8 1 2 0 -0.0028 14 0 0 0 9.88E+06 3.24E+06 - - - 5.4428 0.9996 221125_WJC_METTL3_EV_vs_WT_F02.15120.15120.2 0.00198 16-Aug K.YDGIILPGK.- "sp|P62913|RL11_HUMAN,tr|Q5VVC8|Q5VVC8_HUMAN" 2 974.5437 1.17 15036 15120 2 974.542488 488.2791 60S ribosomal protein L11 OS=Homo sapiens OX=9606 GN=RPL11 PE=1 SV=2 5.83 2949.4 - 1.33E+07 - - - -1.2262 - 1.729 0.413 - 207.9 1 2 0 -0.0012 9 0 0 0 4.77E+09 4.07E+09 - - - 3.6751 0.993 221125_WJC_METTL3_EV_vs_WT_F02.15121.15121.2 7.08E-06 13/24 R.VYTADPYHALAPA.A "sp|O43251|RFOX2_HUMAN,tr|B0QYV1|B0QYV1_HUMAN,tr|A0A0G2JRD1|A0A0G2JRD1_HUMAN,tr|A0A0G2JRA5|A0A0G2JRA5_HUMAN,tr|S4R3K7|S4R3K7_HUMAN" 5 1387.6772 - 15037 15121 2 1387.677596 694.8459 RNA binding protein fox-1 homolog 2 OS=Homo sapiens OX=9606 GN=RBFOX2 PE=1 SV=3 5.08 2949.5 - 1.27E+06 - - - 0.2738 - 2.168 0.534 - 288.6 1 1 0 0.0004 13 0 0 0 - - - - - 4.971 0.996 221125_WJC_METTL3_EV_vs_WT_F02.15124.15124.2 0.0156 22-Dec R.AGLLQQPPALGR.G sp|O00716|E2F3_HUMAN 1 1219.7037 3.91 15040 15124 2 1219.699106 610.8591 Transcription factor E2F3 OS=Homo sapiens OX=9606 GN=E2F3 PE=1 SV=1 9.79 2949.9 - 535791 - - - -3.7714 - 2.208 0.255 - 366.7 1 2 0 -0.0046 12 0 0 0 2.01E+07 5.14E+06 - - - 3.0071 0.9997 221125_WJC_METTL3_EV_vs_WT_F02.15125.15125.2 0.00337 20-Dec K.ALLELQQTTVK[136.11].E "sp|Q7Z589|EMSY_HUMAN,tr|E9PMC9|E9PMC9_HUMAN" 2 1250.7326 0.57 15041 15125 2 1250.734037 626.3736 BRCA2-interacting transcriptional repressor EMSY OS=Homo sapiens OX=9606 GN=EMSY PE=1 SV=2 6.05 2950 - 508284 - - - 1.1865 - 2.551 0.32 - 584 1 2 0 0.0015 11 0 0 0 8.61E+06 1.50E+07 - - - 3.9375 0.9969 221125_WJC_METTL3_EV_vs_WT_F02.15127.15127.2 0.098 12-Jul R.GNFLEIK.N "sp|Q14839|CHD4_HUMAN,tr|A0A2R8Y4X2|A0A2R8Y4X2_HUMAN,tr|A0A2U3TZM0|A0A2U3TZM0_HUMAN,tr|A0A2R8YD40|A0A2R8YD40_HUMAN,tr|A0A2R8Y5J0|A0A2R8Y5J0_HUMAN,tr|A0A2R8Y425|A0A2R8Y425_HUMAN,tr|A0A2R8YFK9|A0A2R8YFK9_HUMAN,tr|A0A0C4DGG9|A0A0C4DGG9_HUMAN,tr|A0A2R8YFD8|A0A2R8YFD8_HUMAN,tr|A0A2R8YDW2|A0A2R8YDW2_HUMAN,tr|A0A2R8Y7I0|A0A2R8Y7I0_HUMAN,tr|F5GWX5|F5GWX5_HUMAN,tr|A0A2R8Y7M9|A0A2R8Y7M9_HUMAN,tr|A0A2R8Y521|A0A2R8Y521_HUMAN,tr|A0A2R8YDJ9|A0A2R8YDJ9_HUMAN,tr|A0A2R8Y212|A0A2R8Y212_HUMAN" 16 819.4491 0.84 15042 15127 2 819.447884 410.7318 Chromodomain-helicase-DNA-binding protein 4 OS=Homo sapiens OX=9606 GN=CHD4 PE=1 SV=2 6 2950.2 - 2.02E+06 - - - -1.4278 - 1.531 0.186 - 343.1 1 2 0 -0.0012 7 0 0 0 4.41E+07 5.26E+07 - - - 1.764 0.9964 221125_WJC_METTL3_EV_vs_WT_F02.15130.15130.2 0.0437 14-Jul K.FAFDYATK.K "sp|O43837|IDH3B_HUMAN,tr|A0A087WZN1|A0A087WZN1_HUMAN,tr|A0A087X2E5|A0A087X2E5_HUMAN" 3 961.4545 0.84 15044 15130 2 961.453051 481.7345 "Isocitrate dehydrogenase [NAD] subunit beta, mitochondrial OS=Homo sapiens OX=9606 GN=IDH3B PE=1 SV=2" 5.83 2950.5 - 1.91E+06 - - - -1.5414 - 1.246 0.269 - 106.9 1 2 0 -0.0015 8 0 0 0 3.11E+07 3.69E+07 - - - 1.6907 0.9848 221125_WJC_METTL3_EV_vs_WT_F02.15131.15131.2 0.326 12-Jul R.DVQEIFR[166.11].M "sp|Q13838|DX39B_HUMAN,sp|O00148|DX39A_HUMAN,tr|A0A140TA18|A0A140TA18_HUMAN,tr|F6UJC5|F6UJC5_HUMAN,tr|F6TRA5|F6TRA5_HUMAN,tr|F6WLT2|F6WLT2_HUMAN,tr|Q5STU3|Q5STU3_HUMAN,tr|A0A140T973|A0A140T973_HUMAN,tr|A0A140T9X9|A0A140T9X9_HUMAN,tr|A0A140T996|A0A140T996_HUMAN,tr|A0A140T9L4|A0A140T9L4_HUMAN,tr|A0A0G2JJZ9|A0A0G2JJZ9_HUMAN,tr|A0A140T9K1|A0A140T9K1_HUMAN,tr|K7EQN7|K7EQN7_HUMAN,tr|A0A140T9X3|A0A140T9X3_HUMAN,tr|H0YCC6|H0YCC6_HUMAN,tr|F6S4E6|F6S4E6_HUMAN,tr|A0A0A0MT12|A0A0A0MT12_HUMAN" 18 915.469 1.07 15045 15131 2 915.467285 458.7418 Spliceosome RNA helicase DDX39B OS=Homo sapiens OX=9606 GN=DDX39B PE=1 SV=1 4.37 2950.5 - 7.51E+06 - - - -1.8198 - 1.303 0.139 - 209.2 2 2 0 -0.0017 7 0 0 0 2.77E+08 2.59E+08 - - - 0.7713 0.9716 221125_WJC_METTL3_EV_vs_WT_F02.15132.15132.2 1.53 16-Aug R.LAILQVGNR[166.11].D "sp|P11586|C1TC_HUMAN,tr|F5H2F4|F5H2F4_HUMAN,tr|V9GYY3|V9GYY3_HUMAN" 3 992.6006 1.44 15046 15132 2 992.598669 497.3076 "C-1-tetrahydrofolate synthase, cytoplasmic OS=Homo sapiens OX=9606 GN=MTHFD1 PE=1 SV=4" 9.75 2950.6 - 4.49E+06 - - - -1.9796 - 1.666 0.015 - 208 3 2 0 -0.002 9 0 0 0 2.16E+08 1.50E+08 - - - 0.4147 0.9998 221125_WJC_METTL3_EV_vs_WT_F02.15135.15135.2 0.000142 22-Dec R.TVIIEQSWGSPK[136.11].V "sp|P10809|CH60_HUMAN,tr|C9JL25|C9JL25_HUMAN,tr|A0A7I2V2X6|A0A7I2V2X6_HUMAN,tr|A0A7I2YQK6|A0A7I2YQK6_HUMAN,tr|A0A7I2V599|A0A7I2V599_HUMAN,tr|E7EXB4|E7EXB4_HUMAN,tr|C9JL19|C9JL19_HUMAN,tr|A0A7I2YQ71|A0A7I2YQ71_HUMAN,tr|E7ESH4|E7ESH4_HUMAN,tr|A0A7I2V5M1|A0A7I2V5M1_HUMAN,tr|A0A7I2V5K3|A0A7I2V5K3_HUMAN,tr|A0A7I2V369|A0A7I2V369_HUMAN,tr|C9JCQ4|C9JCQ4_HUMAN" 13 1351.7227 1.44 15049 15135 2 1351.721411 676.8686 "60 kDa heat shock protein, mitochondrial OS=Homo sapiens OX=9606 GN=HSPD1 PE=1 SV=2" 5.66 2951 - 686286 - - - -0.9654 - 2.345 0.459 - 443.1 1 2 0 -0.0013 12 0 0 0 2.97E+07 2.06E+07 - - - 4.6733 0.9999 221125_WJC_METTL3_EV_vs_WT_F02.15136.15136.2 3.43E-05 22-Dec R.TVIIEQSWGSPK.V "sp|P10809|CH60_HUMAN,tr|C9JL25|C9JL25_HUMAN,tr|A0A7I2V2X6|A0A7I2V2X6_HUMAN,tr|A0A7I2YQK6|A0A7I2YQK6_HUMAN,tr|A0A7I2V599|A0A7I2V599_HUMAN,tr|E7EXB4|E7EXB4_HUMAN,tr|C9JL19|C9JL19_HUMAN,tr|A0A7I2YQ71|A0A7I2YQ71_HUMAN,tr|E7ESH4|E7ESH4_HUMAN,tr|A0A7I2V5M1|A0A7I2V5M1_HUMAN,tr|A0A7I2V5K3|A0A7I2V5K3_HUMAN,tr|A0A7I2V369|A0A7I2V369_HUMAN,tr|C9JCQ4|C9JCQ4_HUMAN" 13 1343.7085 1.44 15050 15136 2 1343.706838 672.8615 "60 kDa heat shock protein, mitochondrial OS=Homo sapiens OX=9606 GN=HSPD1 PE=1 SV=2" 5.66 2951.1 - 650002 - - - -1.2488 - 2.561 0.511 - 496.6 1 2 0 -0.0017 12 0 0 0 2.97E+07 2.06E+07 - - - 5.2891 0.9998 221125_WJC_METTL3_EV_vs_WT_F02.15139.15139.2 4.44E-06 13/18 R.YPVNSVNILK[136.11].A "sp|P17987|TCPA_HUMAN,tr|E7EQR6|E7EQR6_HUMAN,tr|E7ERF2|E7ERF2_HUMAN" 3 1153.6587 0.48 15052 15139 2 1153.657397 577.8366 T-complex protein 1 subunit alpha OS=Homo sapiens OX=9606 GN=TCP1 PE=1 SV=1 8.59 2951.4 - 9.38E+07 - - - -1.0939 - 2.371 0.397 - 659.7 1 2 0 -0.0013 10 0 0 0 1.53E+09 3.17E+09 - - - 4.3826 0.9654 221125_WJC_METTL3_EV_vs_WT_F02.15140.15140.2 0.043 14-Aug R.FSGVPDRF.S "sp|A0A075B6R9|KVD24_HUMAN,sp|A0A0C4DH68|KV224_HUMAN,sp|A2NJV5|KV229_HUMAN,sp|A0A075B6S2|KVD29_HUMAN,sp|A0A0A0MRZ7|KVD26_HUMAN" 5 923.4501 218.85 15053 15140 2 923.448728 462.7323 Probable non-functional immunoglobulin kappa variable 2D-24 OS=Homo sapiens OX=9606 GN=IGKV2D-24 PE=1 SV=1 5.84 2951.5 - 4.24E+07 - - - -1.5041 - 1.624 0.379 - 219.6 1 1 0 -0.0014 8 0 0 0 1.87E+09 8.56E+06 - - - 3.3023 0.9901 221125_WJC_METTL3_EV_vs_WT_F02.15141.15141.2 0.643 12-Jul R.DVQEIFR.M "sp|Q13838|DX39B_HUMAN,sp|O00148|DX39A_HUMAN,tr|A0A140TA18|A0A140TA18_HUMAN,tr|F6UJC5|F6UJC5_HUMAN,tr|F6TRA5|F6TRA5_HUMAN,tr|F6WLT2|F6WLT2_HUMAN,tr|Q5STU3|Q5STU3_HUMAN,tr|A0A140T973|A0A140T973_HUMAN,tr|A0A140T9X9|A0A140T9X9_HUMAN,tr|A0A140T996|A0A140T996_HUMAN,tr|A0A140T9L4|A0A140T9L4_HUMAN,tr|A0A0G2JJZ9|A0A0G2JJZ9_HUMAN,tr|A0A140T9K1|A0A140T9K1_HUMAN,tr|K7EQN7|K7EQN7_HUMAN,tr|A0A140T9X3|A0A140T9X3_HUMAN,tr|H0YCC6|H0YCC6_HUMAN,tr|F6S4E6|F6S4E6_HUMAN,tr|A0A0A0MT12|A0A0A0MT12_HUMAN" 18 905.4607 1.07 15054 15141 2 905.458892 453.7376 Spliceosome RNA helicase DDX39B OS=Homo sapiens OX=9606 GN=DDX39B PE=1 SV=1 4.37 2951.5 - 9.29E+06 - - - -1.9758 - 1.278 0.18 - 216.4 1 2 0 -0.0018 7 0 0 0 2.77E+08 2.59E+08 - - - 1.1472 0.9988 221125_WJC_METTL3_EV_vs_WT_F02.15144.15144.2 0.001 14-Aug R.AQVSLLIR.R "sp|Q99623|PHB2_HUMAN,tr|F5H3X6|F5H3X6_HUMAN,tr|A0A7I2V5F0|A0A7I2V5F0_HUMAN,tr|F5GWA7|F5GWA7_HUMAN,tr|J3KPX7|J3KPX7_HUMAN,tr|F5GY37|F5GY37_HUMAN" 6 898.56 1.09 15057 15144 2 898.557502 450.2873 Prohibitin-2 OS=Homo sapiens OX=9606 GN=PHB2 PE=1 SV=2 9.79 2951.6 - 2.81E+06 - - - -2.7822 - 1.715 0.388 - 279.2 1 2 0 -0.0025 8 0 0 0 1.33E+08 1.22E+08 - - - 3.5328 0.9942 221125_WJC_METTL3_EV_vs_WT_F02.15145.15145.2 0.00582 14-Jul R.AQVSLLIR[166.11].R "sp|Q99623|PHB2_HUMAN,tr|F5H3X6|F5H3X6_HUMAN,tr|A0A7I2V5F0|A0A7I2V5F0_HUMAN,tr|F5GWA7|F5GWA7_HUMAN,tr|J3KPX7|J3KPX7_HUMAN,tr|F5GY37|F5GY37_HUMAN" 6 908.5683 1.09 15058 15145 2 908.567036 455.2914 Prohibitin-2 OS=Homo sapiens OX=9606 GN=PHB2 PE=1 SV=2 9.79 2951.7 - 3.85E+06 - - - -1.3604 - 1.373 0.17 - 132.2 1 2 0 -0.0012 8 0 0 0 1.33E+08 1.22E+08 - - - 1.2523 0.9998 221125_WJC_METTL3_EV_vs_WT_F02.15146.15146.2 0.0124 18-Dec R.LAYQELQIDR[166.11].K "sp|Q8N6H7|ARFG2_HUMAN,tr|E9PIY6|E9PIY6_HUMAN,tr|E9PQP3|E9PQP3_HUMAN,tr|H0YDN9|H0YDN9_HUMAN,tr|G5E9L0|G5E9L0_HUMAN,tr|A0A0D9SF70|A0A0D9SF70_HUMAN" 6 1257.6593 1.2 15059 15146 2 1257.659269 629.8369 ADP-ribosylation factor GTPase-activating protein 2 OS=Homo sapiens OX=9606 GN=ARFGAP2 PE=1 SV=1 4.37 2951.8 - 1.76E+06 - - - -0.0016 - 2.048 0.398 - 508.5 1 2 0 0 10 0 0 0 3.59E+08 3.00E+08 - - - 3.9816 0.999 221125_WJC_METTL3_EV_vs_WT_F02.15148.15148.2 1.64E-05 16-Sep K.SYLAQFAAR[166.11].A "sp|P78344|IF4G2_HUMAN,tr|E9PKF8|E9PKF8_HUMAN,tr|H0Y3P2|H0Y3P2_HUMAN,tr|H0YE22|H0YE22_HUMAN,tr|D3DQV9|D3DQV9_HUMAN" 5 1035.5377 1.76 15061 15148 2 1035.534407 518.7761 Eukaryotic translation initiation factor 4 gamma 2 OS=Homo sapiens OX=9606 GN=EIF4G2 PE=1 SV=1 8.46 2952 - 1.17E+06 - - - -3.18 - 1.918 0.439 - 314.3 1 2 0 -0.0033 9 0 0 0 2.92E+08 1.66E+08 - - - 4.1666 0.9998 221125_WJC_METTL3_EV_vs_WT_F02.15149.15149.2 6.00E-07 13/22 K.LLAAGFDNSC[160.03]IK[136.11].L sp|O75529|TAF5L_HUMAN 1 1315.6686 0.58 15062 15149 2 1315.666075 658.8416 TAF5-like RNA polymerase II p300\CBP-associated factor-associated factor 65 kDa subunit 5L OS=Homo sapiens OX=9606 GN=TAF5L PE=1 SV=1 5.83 2952.1 - 814141 - - - -1.8987 - 2.487 0.54 - 575.3 1 2 0 -0.0025 12 0 0 0 2.25E+07 3.87E+07 - - - 5.4259 0.9993 221125_WJC_METTL3_EV_vs_WT_F02.15152.15152.2 0.00422 12-Jul K.FYIDPYK[136.11].L sp|Q9NY12|GAR1_HUMAN 1 952.4786 0.9 15064 15152 2 952.477007 477.2466 H\ACA ribonucleoprotein complex subunit 1 OS=Homo sapiens OX=9606 GN=GAR1 PE=1 SV=1 5.83 2952.5 - 2.85E+06 - - - -1.641 - 1.507 0.387 - 176.5 1 2 0 -0.0016 7 0 0 0 1.25E+08 1.39E+08 - - - 3.1984 0.9998 221125_WJC_METTL3_EV_vs_WT_F02.15155.15155.2 5.66E-06 18-Oct R.GLESDVAELR.A sp|Q03252|LMNB2_HUMAN 1 1087.551 1.2 15066 15155 2 1087.549003 544.7828 Lamin-B2 OS=Homo sapiens OX=9606 GN=LMNB2 PE=1 SV=4 4.14 2952.7 - 4.03E+06 - - - -1.793 - 2.134 0.494 - 370.2 1 2 0 -0.0019 10 0 0 0 1.39E+08 1.16E+08 - - - 4.8049 0.9997 221125_WJC_METTL3_EV_vs_WT_F02.15156.15156.2 0.00131 16-Sep K.SYLAQFAAR.A "sp|P78344|IF4G2_HUMAN,tr|E9PKF8|E9PKF8_HUMAN,tr|H0Y3P2|H0Y3P2_HUMAN,tr|H0YE22|H0YE22_HUMAN,tr|D3DQV9|D3DQV9_HUMAN" 5 1025.5294 1.3 15067 15156 2 1025.528545 513.772 Eukaryotic translation initiation factor 4 gamma 2 OS=Homo sapiens OX=9606 GN=EIF4G2 PE=1 SV=1 8.46 2952.8 - 3.49E+06 - - - -0.863 - 1.821 0.395 - 271.4 1 2 0 -0.0009 9 0 0 0 2.95E+08 2.27E+08 - - - 3.6922 0.9989 221125_WJC_METTL3_EV_vs_WT_F02.15157.15157.2 0.000219 18-Oct R.GLESDVAELR[166.11].A sp|Q03252|LMNB2_HUMAN 1 1097.5592 1.22 15068 15157 2 1097.554975 549.7869 Lamin-B2 OS=Homo sapiens OX=9606 GN=LMNB2 PE=1 SV=4 4.14 2952.9 - 2.42E+06 - - - -3.8704 - 1.98 0.507 - 314.4 1 2 0 -0.0042 10 0 0 0 1.41E+08 1.16E+08 - - - 4.6911 1 221125_WJC_METTL3_EV_vs_WT_F02.15158.15158.2 4.50E-08 16/24 R.VETGVLK[136.11]PGMVVT.F "sp|P68104|EF1A1_HUMAN,sp|Q5VTE0|EF1A3_HUMAN,tr|A0A7I2V659|A0A7I2V659_HUMAN,tr|A0A7I2V3H3|A0A7I2V3H3_HUMAN,tr|A0A7I2V5N4|A0A7I2V5N4_HUMAN,tr|A0A087WVQ9|A0A087WVQ9_HUMAN" 6 1336.7516 0.33 15069 15158 2 1336.748468 669.3831 Elongation factor 1-alpha 1 OS=Homo sapiens OX=9606 GN=EEF1A1 PE=1 SV=1 5.97 2953 - 1.84E+06 - - - -2.3235 - 2.906 0.584 - 735.6 1 1 0 -0.0031 13 0 0 0 3.07E+08 9.32E+08 - - - 6.0914 0.9853 221125_WJC_METTL3_EV_vs_WT_F02.15160.15160.2 0.00054 13/18 R.FPGQLNADLR.K "sp|P04350|TBB4A_HUMAN,sp|Q9BVA1|TBB2B_HUMAN,sp|A6NNZ2|TBB8B_HUMAN,sp|P07437|TBB5_HUMAN,sp|Q13509|TBB3_HUMAN,sp|Q13885|TBB2A_HUMAN,sp|P68371|TBB4B_HUMAN,sp|Q9BUF5|TBB6_HUMAN,sp|Q3ZCM7|TBB8_HUMAN,sp|Q9H4B7|TBB1_HUMAN,tr|M0R2D3|M0R2D3_HUMAN,tr|A0A0B4J269|A0A0B4J269_HUMAN,tr|Q5ST81|Q5ST81_HUMAN,tr|Q5JP53|Q5JP53_HUMAN,tr|K7ESM5|K7ESM5_HUMAN,tr|A0A075B736|A0A075B736_HUMAN,tr|G3V2A3|G3V2A3_HUMAN,tr|Q5SQY0|Q5SQY0_HUMAN" 18 1129.588 0.51 15071 15160 2 1129.580162 565.8013 Tubulin beta-4A chain OS=Homo sapiens OX=9606 GN=TUBB4A PE=1 SV=2 5.84 2953.2 - 1.17E+06 - - - -6.945 - 2.094 0.4 - 552.3 1 2 0 -0.0078 10 0 0 0 5.74E+07 1.12E+08 - - - 4.0559 0.9998 221125_WJC_METTL3_EV_vs_WT_F02.15161.15161.2 0.0031 20-Nov K.LSAMMGAVAEK[136.11].K "sp|Q86U44|MTA70_HUMAN,tr|F5H6D8|F5H6D8_HUMAN,tr|H0YFV6|H0YFV6_HUMAN,tr|B4DTN4|B4DTN4_HUMAN" 4 1114.5606 0.001 15072 15161 2 1114.559319 558.2876 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 6 2953.4 - 708202 - - - -1.1511 - 2.392 0.431 - 240.6 1 2 0 -0.0013 11 0 0 0 0.00E+00 1.37E+07 - - - 4.5833 0.9999 221125_WJC_METTL3_EV_vs_WT_F02.15164.15164.2 1.48E-06 14/26 R.LVVPATQC[160.03]GSLIGK[136.11].G sp|Q15365|PCBP1_HUMAN 1 1449.8105 0.76 15073 15164 2 1449.810757 725.9125 Poly(rC)-binding protein 1 OS=Homo sapiens OX=9606 GN=PCBP1 PE=1 SV=2 8.22 2953.8 - 2.07E+06 - - - 0.1869 - 2.302 0.573 - 421.8 1 2 0 0.0003 14 0 0 0 3.58E+08 4.70E+08 - - - 5.3654 0.9884 221125_WJC_METTL3_EV_vs_WT_F02.15165.15165.2 9.04E-05 13/24 R.VETGVLKPGMVVT.F "sp|P68104|EF1A1_HUMAN,sp|Q5VTE0|EF1A3_HUMAN,tr|A0A7I2V659|A0A7I2V659_HUMAN,tr|A0A7I2V3H3|A0A7I2V3H3_HUMAN,tr|A0A7I2V5N4|A0A7I2V5N4_HUMAN,tr|A0A087WVQ9|A0A087WVQ9_HUMAN" 6 1328.7374 0.33 15074 15165 2 1328.735234 665.376 Elongation factor 1-alpha 1 OS=Homo sapiens OX=9606 GN=EEF1A1 PE=1 SV=1 5.97 2953.9 - 1.89E+06 - - - -1.6106 - 2.689 0.451 - 473.4 1 1 0 -0.0021 13 0 0 0 3.07E+08 9.32E+08 - - - 4.9101 0.9998 221125_WJC_METTL3_EV_vs_WT_F02.15166.15166.2 0.00433 18-Nov R.LAYQELQIDR.K "sp|Q8N6H7|ARFG2_HUMAN,tr|E9PIY6|E9PIY6_HUMAN,tr|E9PQP3|E9PQP3_HUMAN,tr|H0YDN9|H0YDN9_HUMAN,tr|G5E9L0|G5E9L0_HUMAN,tr|A0A0D9SF70|A0A0D9SF70_HUMAN" 6 1247.651 1.2 15075 15166 2 1247.650305 624.8328 ADP-ribosylation factor GTPase-activating protein 2 OS=Homo sapiens OX=9606 GN=ARFGAP2 PE=1 SV=1 4.37 2953.9 - 6.18E+06 - - - -0.5578 - 2.221 0.413 - 475.3 1 2 0 -0.0007 10 0 0 0 3.59E+08 3.00E+08 - - - 4.3185 0.9992 221125_WJC_METTL3_EV_vs_WT_F02.15169.15169.2 0.0107 18-Nov R.AELIVQPELK.Y sp|P15924|DESP_HUMAN 1 1138.6598 126.66 15076 15169 2 1138.660029 570.3372 Desmoplakin OS=Homo sapiens OX=9606 GN=DSP PE=1 SV=3 4.53 2954.3 - 2.22E+06 - - - 0.2231 - 1.758 0.262 - 496.1 1 2 0 0.0003 10 0 0 0 6.84E+08 5.40E+06 - - - 2.5508 0.9958 221125_WJC_METTL3_EV_vs_WT_F02.15173.15173.2 5.23E-08 13/26 R.LVVPATQC[160.03]GSLIGK.G sp|Q15365|PCBP1_HUMAN 1 1441.7963 0.76 15078 15173 2 1441.78712 721.9054 Poly(rC)-binding protein 1 OS=Homo sapiens OX=9606 GN=PCBP1 PE=1 SV=2 8.22 2954.8 - 2.14E+06 - - - -6.3573 - 2.307 0.604 - 414.1 1 2 0 -0.0092 14 0 0 0 3.58E+08 4.70E+08 - - - 5.597 0.999 221125_WJC_METTL3_EV_vs_WT_F02.15174.15174.2 1.32E-07 13/20 K.TADDPSLSLIK[136.11].Y "sp|P39656|OST48_HUMAN,tr|U3KQ84|U3KQ84_HUMAN,tr|A0A0C4DGS1|A0A0C4DGS1_HUMAN" 3 1166.6274 1.42 15079 15174 2 1166.622718 584.321 Dolichyl-diphosphooligosaccharide--protein glycosyltransferase 48 kDa subunit OS=Homo sapiens OX=9606 GN=DDOST PE=1 SV=4 4.21 2954.9 - 1.54E+06 - - - -4.0296 - 2.383 0.506 - 447 1 2 0 -0.0047 11 0 0 0 9.45E+07 6.64E+07 - - - 5.126 0.996 221125_WJC_METTL3_EV_vs_WT_F02.15177.15177.2 0.0464 12-Jun K.FYIDPYK.L sp|Q9NY12|GAR1_HUMAN 1 944.4644 0.9 15080 15177 2 944.462969 473.2395 H\ACA ribonucleoprotein complex subunit 1 OS=Homo sapiens OX=9606 GN=GAR1 PE=1 SV=1 5.83 2955.3 - 4.48E+06 - - - -1.4834 - 1.174 0.276 - 128.6 1 2 0 -0.0014 7 0 0 0 1.25E+08 1.39E+08 - - - 1.5874 0.9977 221125_WJC_METTL3_EV_vs_WT_F02.15178.15178.2 0.0271 12-Jul R.SQQWLLR.N "sp|Q10472|GALT1_HUMAN,sp|Q8IUC8|GLT13_HUMAN,tr|H7C2I5|H7C2I5_HUMAN" 3 929.5083 1.1 15081 15178 2 929.506476 465.7614 Polypeptide N-acetylgalactosaminyltransferase 1 OS=Homo sapiens OX=9606 GN=GALNT1 PE=1 SV=1 9.47 2955.3 - 4.92E+06 - - - -1.9623 - 1.39 0.299 - 328.7 1 2 0 -0.0018 7 0 0 0 9.40E+07 8.55E+07 - - - 2.2923 0.9913 221125_WJC_METTL3_EV_vs_WT_F02.15179.15179.2 0.0929 14-Jul K.DVLYPSLK.E "sp|P40855|PEX19_HUMAN,tr|H0YJ60|H0YJ60_HUMAN,tr|H0YDY4|H0YDY4_HUMAN,tr|Q5QNY5|Q5QNY5_HUMAN" 4 933.5171 2.81 15082 15179 2 933.518843 467.7658 Peroxisomal biogenesis factor 19 OS=Homo sapiens OX=9606 GN=PEX19 PE=1 SV=1 5.83 2955.5 - 2.24E+06 - - - 1.8307 - 1.261 0.202 - 148.7 1 2 0 0.0017 8 0 0 0 6.87E+07 2.44E+07 - - - 1.2319 0.9368 221125_WJC_METTL3_EV_vs_WT_F02.15185.15185.2 0.041 12-Aug K.SAEFLLH.M "sp|P18621|RL17_HUMAN,tr|A0A087WWH0|A0A087WWH0_HUMAN,tr|J3QS96|J3QS96_HUMAN,tr|J3QLC8|J3QLC8_HUMAN,tr|J3QQT2|J3QQT2_HUMAN,tr|A0A087WY81|A0A087WY81_HUMAN,tr|A0A0A0MRF8|A0A0A0MRF8_HUMAN,tr|J3KRB3|J3KRB3_HUMAN,tr|J3KRX5|J3KRX5_HUMAN,tr|A0A087WXM6|A0A087WXM6_HUMAN,tr|A0A0A6YYL6|A0A0A6YYL6_HUMAN" 11 815.4178 - 15086 15185 2 815.416994 408.7162 60S ribosomal protein L17 OS=Homo sapiens OX=9606 GN=RPL17 PE=1 SV=3 5.22 2956.2 - 1.26E+06 - - - -0.932 - 1.501 0.281 - 278.8 1 1 0 -0.0008 7 0 0 0 - - - - - 2.4031 0.9984 221125_WJC_METTL3_EV_vs_WT_F02.15189.15189.2 0.0785 14-Aug K.VLVPQIPR[166.11].L sp|Q10469|MGAT2_HUMAN 1 930.589 1.69 15088 15189 2 930.588265 466.3018 "Alpha-1,6-mannosyl-glycoprotein 2-beta-N-acetylglucosaminyltransferase OS=Homo sapiens OX=9606 GN=MGAT2 PE=1 SV=1" 9.72 2956.6 - 2.45E+06 - - - -0.7973 - 1.319 0.292 - 301.8 1 2 0 -0.0007 8 0 0 0 1.52E+08 9.03E+07 - - - 2.0325 0.9996 221125_WJC_METTL3_EV_vs_WT_F02.15190.15190.2 0.00903 16-Sep R.NELPTVAFK.A "sp|Q9NVN8|GNL3L_HUMAN,tr|A0A6I8PL80|A0A6I8PL80_HUMAN,tr|A0A6I8PS19|A0A6I8PS19_HUMAN" 3 1017.5495 0.6 15089 15190 2 1017.549188 509.782 Guanine nucleotide-binding protein-like 3-like protein OS=Homo sapiens OX=9606 GN=GNL3L PE=1 SV=1 6 2956.8 - 2.10E+06 - - - -0.3027 - 2.003 0.304 - 292.5 1 2 0 -0.0003 9 0 0 0 4.41E+07 7.30E+07 - - - 3.2959 0.9998 221125_WJC_METTL3_EV_vs_WT_F02.15191.15191.2 0.0176 18-Oct K.VLQSALAAIR[166.11].H "sp|Q12905|ILF2_HUMAN,tr|B4DY09|B4DY09_HUMAN" 2 1050.6425 1.13 15090 15191 2 1050.642904 526.3285 Interleukin enhancer-binding factor 2 OS=Homo sapiens OX=9606 GN=ILF2 PE=1 SV=2 9.72 2956.9 - 1.29E+06 - - - 0.3855 - 2.01 0.392 - 336.4 1 2 0 0.0004 10 0 0 0 6.20E+08 5.49E+08 - - - 3.8849 0.9997 221125_WJC_METTL3_EV_vs_WT_F02.15192.15192.2 6.10E-05 16-Sep R.VELPTC[160.03]MYR[166.11].L "sp|Q13155|AIMP2_HUMAN,tr|F8WCL2|F8WCL2_HUMAN" 2 1177.5499 2.64 15091 15192 2 1177.551847 589.7822 Aminoacyl tRNA synthase complex-interacting multifunctional protein 2 OS=Homo sapiens OX=9606 GN=AIMP2 PE=1 SV=2 5.97 2957 - 742097 - - - 1.6356 - 1.902 0.488 - 325.6 1 2 0 0.0019 9 0 0 0 1.05E+08 3.98E+07 - - - 4.5047 0.9993 221125_WJC_METTL3_EV_vs_WT_F02.15197.15197.2 0.00172 18-Aug K.VLQSALAAIR.H "sp|Q12905|ILF2_HUMAN,tr|B4DY09|B4DY09_HUMAN" 2 1040.6342 1.13 15093 15197 2 1040.635424 521.3244 Interleukin enhancer-binding factor 2 OS=Homo sapiens OX=9606 GN=ILF2 PE=1 SV=2 9.72 2957.6 - 2.71E+06 - - - 1.1483 - 1.927 0.299 - 140.7 1 2 0 0.0012 10 0 0 0 6.20E+08 5.49E+08 - - - 3.08 0.9958 221125_WJC_METTL3_EV_vs_WT_F02.15198.15198.2 0.0383 14-Sep R.VVIQEMLK[136.11].T sp|P40938|RFC3_HUMAN 1 966.5663 2.36 15094 15198 2 966.562896 484.2904 Replication factor C subunit 3 OS=Homo sapiens OX=9606 GN=RFC3 PE=1 SV=2 5.97 2957.7 - 782810 - - - -3.5621 - 1.641 0.307 - 236.5 1 2 0 -0.0034 8 0 0 0 3.98E+07 1.69E+07 - - - 2.8012 0.9996 221125_WJC_METTL3_EV_vs_WT_F02.15199.15199.2 0.016 13/22 K.VVSTLPSTVLGK.G "sp|Q9UKD1|GMEB2_HUMAN,tr|Q5JTV1|Q5JTV1_HUMAN" 2 1199.7125 1.76 15095 15199 2 1199.712556 600.8635 Glucocorticoid modulatory element-binding protein 2 OS=Homo sapiens OX=9606 GN=GMEB2 PE=1 SV=1 8.72 2957.9 - 2.65E+06 - - - 0.0142 - 2.168 0.304 - 436.7 1 2 0 0 12 0 0 0 3.78E+07 2.14E+07 - - - 3.3224 0.9972 221125_WJC_METTL3_EV_vs_WT_F02.15200.15200.2 0.00118 20-Dec R.GLVGNPLPSVR.R "sp|Q9H583|HEAT1_HUMAN,tr|Q5T3Q7|Q5T3Q7_HUMAN" 2 1107.64 1.04 15096 15200 2 1107.635791 554.8273 HEAT repeat-containing protein 1 OS=Homo sapiens OX=9606 GN=HEATR1 PE=1 SV=3 9.75 2958 - 1.29E+06 - - - -3.8388 - 1.876 0.367 - 370.2 1 2 0 -0.0043 11 0 0 0 5.71E+07 5.51E+07 - - - 3.4523 0.9985 221125_WJC_METTL3_EV_vs_WT_F02.15203.15203.2 0.0141 18-Aug R.IPEQTYITLK.L "sp|Q5SW79|CE170_HUMAN,tr|E5RFU8|E5RFU8_HUMAN,tr|E5RIH6|E5RIH6_HUMAN,tr|E5RJT5|E5RJT5_HUMAN" 4 1204.6703 0.85 15098 15203 2 1204.668607 603.3424 Centrosomal protein of 170 kDa OS=Homo sapiens OX=9606 GN=CEP170 PE=1 SV=1 6 2958.3 - 1.02E+06 - - - -1.4386 - 1.481 0.302 - 154.5 1 2 0 -0.0017 10 0 0 0 4.89E+07 5.77E+07 - - - 2.3672 0.9987 221125_WJC_METTL3_EV_vs_WT_F02.15206.15206.2 0.011 20-Sep R.TLEVEIEPGVR.D "sp|Q9UBS4|DJB11_HUMAN,tr|H7C2Y5|H7C2Y5_HUMAN" 2 1240.6663 0.91 15099 15206 2 1240.663582 621.3404 DnaJ homolog subfamily B member 11 OS=Homo sapiens OX=9606 GN=DNAJB11 PE=1 SV=1 4.25 2958.7 - 878124 - - - -2.2045 - 1.831 0.31 - 210.4 1 2 0 -0.0027 11 0 0 0 2.57E+07 2.82E+07 - - - 2.9661 0.9599 221125_WJC_METTL3_EV_vs_WT_F02.15207.15207.2 0.00267 20-Oct R.QLVEADINGLR.R "sp|Q14532|K1H2_HUMAN,sp|O76013|KRT36_HUMAN" 2 1226.6619 159.7 15100 15207 2 1226.653503 614.3382 "Keratin, type I cuticular Ha2 OS=Homo sapiens OX=9606 GN=KRT32 PE=1 SV=3" 4.37 2958.9 - 946926 - - - -6.8454 - 1.537 0.356 - 184.1 1 2 0 -0.0084 11 0 0 0 2.20E+07 1.38E+05 - - - 2.8306 0.9989 221125_WJC_METTL3_EV_vs_WT_F02.15208.15208.2 0.00039 18-Oct R.IPEQTYITLK[136.11].L "sp|Q5SW79|CE170_HUMAN,tr|E5RFU8|E5RFU8_HUMAN,tr|E5RIH6|E5RIH6_HUMAN,tr|E5RJT5|E5RJT5_HUMAN" 4 1212.6845 0.85 15101 15208 2 1212.680098 607.3495 Centrosomal protein of 170 kDa OS=Homo sapiens OX=9606 GN=CEP170 PE=1 SV=1 6 2959 - 915890 - - - -3.6629 - 1.953 0.477 - 329.8 1 2 0 -0.0044 10 0 0 0 4.82E+07 5.68E+07 - - - 4.4311 0.9933 221125_WJC_METTL3_EV_vs_WT_F02.15215.15215.2 0.11 16-Oct R.AGLQFPVGR[166.11].V "sp|P16104|H2AX_HUMAN,sp|Q9BTM1|H2AJ_HUMAN,sp|Q93077|H2A1C_HUMAN,sp|Q99878|H2A1J_HUMAN,sp|Q16777|H2A2C_HUMAN,sp|Q8IUE6|H2A2B_HUMAN,sp|Q96QV6|H2A1A_HUMAN,sp|P0C0S5|H2AZ_HUMAN,sp|P04908|H2A1B_HUMAN,sp|P20671|H2A1D_HUMAN,sp|P0C0S8|H2A1_HUMAN,sp|Q6FI13|H2A2A_HUMAN,sp|Q96KK5|H2A1H_HUMAN,sp|Q71UI9|H2AV_HUMAN,sp|Q7L7L0|H2A3_HUMAN,tr|A0A0U1RR32|A0A0U1RR32_HUMAN,tr|A0A0U1RRH7|A0A0U1RRH7_HUMAN,tr|A0A3B3IS11|A0A3B3IS11_HUMAN,tr|C9J0D1|C9J0D1_HUMAN,tr|A0A494C189|A0A494C189_HUMAN" 20 953.5322 1.16 15104 15215 2 953.530144 477.7734 Histone H2AX OS=Homo sapiens OX=9606 GN=H2AX PE=1 SV=2 9.79 2959.8 - 3.67E+06 - - - -2.1772 - 1.593 0.156 - 380.6 1 2 0 -0.0021 9 0 0 0 1.35E+10 1.16E+10 - - - 1.5396 0.9919 221125_WJC_METTL3_EV_vs_WT_F02.15218.15218.2 0.131 12-Jun K.SVTAFFK.W "sp|Q04637|IF4G1_HUMAN,tr|E7EUU4|E7EUU4_HUMAN,tr|E9PGM1|E9PGM1_HUMAN,tr|E7EX73|E7EX73_HUMAN,tr|A0A7I2Y1C3|A0A7I2Y1C3_HUMAN" 5 798.4276 0.71 15106 15218 2 798.424835 400.2211 Eukaryotic translation initiation factor 4 gamma 1 OS=Homo sapiens OX=9606 GN=EIF4G1 PE=1 SV=4 8.47 2960.1 - 1.29E+06 - - - -3.4505 - 1.334 0.296 - 126.1 1 2 0 -0.0028 7 0 0 0 4.62E+07 6.51E+07 - - - 2.1395 0.9997 221125_WJC_METTL3_EV_vs_WT_F02.15219.15219.2 3.45E-06 22-Nov R.IFTSIGEDYDER[166.11].V "sp|P35232|PHB_HUMAN,tr|C9JZ20|C9JZ20_HUMAN,tr|E7ESE2|E7ESE2_HUMAN,tr|E9PCW0|E9PCW0_HUMAN,tr|C9JW96|C9JW96_HUMAN" 5 1453.6601 1.35 15107 15219 2 1453.656652 727.8373 Prohibitin OS=Homo sapiens OX=9606 GN=PHB PE=1 SV=1 3.92 2960.3 - 2.07E+06 - - - -2.3437 - 2.228 0.562 - 448.9 1 2 0 -0.0034 12 0 0 0 1.66E+08 1.23E+08 - - - 5.2987 0.9996 221125_WJC_METTL3_EV_vs_WT_F02.15223.15223.2 0.0204 18-Nov K.AVDSLVPIGR[166.11].G "sp|P25705|ATPA_HUMAN,tr|K7ERX7|K7ERX7_HUMAN,tr|K7EK77|K7EK77_HUMAN,tr|K7ENJ4|K7ENJ4_HUMAN" 4 1035.5952 1.45 15109 15223 2 1035.594276 518.8049 "ATP synthase subunit alpha, mitochondrial OS=Homo sapiens OX=9606 GN=ATP5F1A PE=1 SV=1" 5.88 2960.7 - 7.09E+06 - - - -0.9067 - 1.936 0.344 - 412.6 1 2 0 -0.0009 10 0 0 0 9.50E+08 6.56E+08 - - - 3.4255 0.9993 221125_WJC_METTL3_EV_vs_WT_F02.15224.15224.2 0.175 18-Oct K.AVDSLVPIGR.G "sp|P25705|ATPA_HUMAN,tr|K7ERX7|K7ERX7_HUMAN,tr|K7EK77|K7EK77_HUMAN,tr|K7ENJ4|K7ENJ4_HUMAN" 4 1025.5869 1.45 15110 15224 2 1025.58535 513.8007 "ATP synthase subunit alpha, mitochondrial OS=Homo sapiens OX=9606 GN=ATP5F1A PE=1 SV=1" 5.88 2960.7 - 7.50E+06 - - - -1.5552 - 1.737 0.35 - 357.7 1 2 0 -0.0016 10 0 0 0 9.51E+08 6.57E+08 - - - 3.1668 0.9944 221125_WJC_METTL3_EV_vs_WT_F02.15226.15226.2 0.135 16-Nov R.YQGVNLYIK.N "sp|Q13310|PABP4_HUMAN,tr|A0A7I2V5W9|A0A7I2V5W9_HUMAN,tr|H0YEU6|H0YEU6_HUMAN,tr|B1ANR0|B1ANR0_HUMAN,tr|A0A7I2V4L7|A0A7I2V4L7_HUMAN,tr|A0A7I2V598|A0A7I2V598_HUMAN,tr|H0Y5F5|H0Y5F5_HUMAN" 7 1096.5917 1.41 15112 15226 2 1096.588577 549.3031 Polyadenylate-binding protein 4 OS=Homo sapiens OX=9606 GN=PABPC4 PE=1 SV=1 8.5 2960.9 - 1.61E+06 - - - -2.8443 - 1.543 0.24 - 220.2 1 2 0 -0.0031 9 0 0 0 5.20E+08 3.69E+08 - - - 2.0675 0.9999 221125_WJC_METTL3_EV_vs_WT_F02.15229.15229.2 2.51E-06 15/22 M.PLENLEEEGLPK[136.11].N "sp|Q15008|PSMD6_HUMAN,tr|C9J7B7|C9J7B7_HUMAN" 2 1374.7122 1.08 15115 15229 2 1374.713396 688.3634 26S proteasome non-ATPase regulatory subunit 6 OS=Homo sapiens OX=9606 GN=PSMD6 PE=1 SV=1 4.09 2961.3 - 899741 - - - 0.862 - 2.526 0.521 - 513.1 1 2 0 0.0012 12 0 0 0 5.40E+07 4.99E+07 - - - 5.3269 0.9997 221125_WJC_METTL3_EV_vs_WT_F02.15231.15231.2 0.000485 16-Oct K.TGISDVFAK.N "sp|P19338|NUCL_HUMAN,tr|A0A7I2V506|A0A7I2V506_HUMAN,tr|A0A7I2V699|A0A7I2V699_HUMAN,tr|A0A7I2V2U7|A0A7I2V2U7_HUMAN,tr|A0A7I2V3F3|A0A7I2V3F3_HUMAN,tr|A0A7I2V428|A0A7I2V428_HUMAN,tr|A0A7I2V349|A0A7I2V349_HUMAN,tr|H7BY16|H7BY16_HUMAN,tr|A0A7I2V5M5|A0A7I2V5M5_HUMAN,tr|A0A7I2V2S8|A0A7I2V2S8_HUMAN,tr|C9JLB1|C9JLB1_HUMAN" 11 936.4916 2.71 15116 15231 2 936.490126 469.2531 Nucleolin OS=Homo sapiens OX=9606 GN=NCL PE=1 SV=3 5.5 2961.5 - 8.91E+06 - - - -1.6241 - 1.972 0.466 - 284.3 1 2 0 -0.0015 9 0 0 0 7.63E+08 2.81E+08 - - - 4.4469 0.9998 221125_WJC_METTL3_EV_vs_WT_F02.15233.15233.2 0.000131 16-Nov R.YQGVNLYIK[136.11].N "sp|Q13310|PABP4_HUMAN,tr|A0A7I2V5W9|A0A7I2V5W9_HUMAN,tr|H0YEU6|H0YEU6_HUMAN,tr|B1ANR0|B1ANR0_HUMAN,tr|A0A7I2V4L7|A0A7I2V4L7_HUMAN,tr|A0A7I2V598|A0A7I2V598_HUMAN,tr|H0Y5F5|H0Y5F5_HUMAN" 7 1104.6059 3.14 15117 15233 2 1104.605507 553.3102 Polyadenylate-binding protein 4 OS=Homo sapiens OX=9606 GN=PABPC4 PE=1 SV=1 8.5 2961.7 - 3.97E+06 - - - -0.3522 - 1.828 0.475 - 244.2 1 2 0 -0.0004 9 0 0 0 1.38E+09 4.38E+08 - - - 4.2944 0.9955 221125_WJC_METTL3_EV_vs_WT_F02.15240.15240.2 0.00874 14-Aug R.QYMFSSLK.N sp|P13010|XRCC5_HUMAN 1 1002.4845 1.09 15122 15240 2 1002.481496 502.2495 X-ray repair cross-complementing protein 5 OS=Homo sapiens OX=9606 GN=XRCC5 PE=1 SV=3 8.59 2962.5 - 1.35E+06 - - - -2.9497 - 1.409 0.306 - 194 1 2 0 -0.003 8 0 0 0 2.76E+07 2.52E+07 - - - 2.3343 0.9997 221125_WJC_METTL3_EV_vs_WT_F02.15242.15242.2 0.000273 18-Nov K.VLGMDPLPSK[136.11].M sp|Q12906|ILF3_HUMAN 1 1063.5827 1.11 15123 15242 2 1063.580742 532.7986 Interleukin enhancer-binding factor 3 OS=Homo sapiens OX=9606 GN=ILF3 PE=1 SV=3 5.81 2962.7 - 2.51E+06 - - - -1.8569 - 2.202 0.461 - 350.7 1 2 0 -0.002 10 0 0 0 4.74E+08 4.28E+08 - - - 4.6487 0.9996 221125_WJC_METTL3_EV_vs_WT_F02.15245.15245.2 6.33E-05 13/20 R.ILVDQVTGISR[166.11].G "sp|Q12926|ELAV2_HUMAN,tr|B1AM48|B1AM48_HUMAN,tr|C9JB16|C9JB16_HUMAN,tr|A0A0A0MRX1|A0A0A0MRX1_HUMAN" 4 1209.6957 2.03 15126 15245 2 1209.69236 605.8551 ELAV-like protein 2 OS=Homo sapiens OX=9606 GN=ELAVL2 PE=1 SV=2 5.84 2963 - 1.99E+06 - - - -2.7255 - 2.296 0.482 - 670.5 1 2 0 -0.0033 11 0 0 0 1.34E+08 6.60E+07 - - - 4.8485 0.995 221125_WJC_METTL3_EV_vs_WT_F02.15249.15249.2 0.169 16-Aug R.IDISPSTFR[166.11].K "sp|Q9Y2W1|TR150_HUMAN,tr|A0A3B3ITZ9|A0A3B3ITZ9_HUMAN" 2 1044.5479 2.55 15128 15249 2 1044.547036 523.2812 Thyroid hormone receptor-associated protein 3 OS=Homo sapiens OX=9606 GN=THRAP3 PE=1 SV=2 5.84 2963.5 - 4.13E+06 - - - -0.8559 - 1.604 0.107 - 136.5 1 2 0 -0.0009 9 0 0 0 5.31E+09 2.08E+09 - - - 1.198 0.9998 221125_WJC_METTL3_EV_vs_WT_F02.15250.15250.2 1.36E-05 15/22 M.PLENLEEEGLPK.N "sp|Q15008|PSMD6_HUMAN,tr|C9J7B7|C9J7B7_HUMAN" 2 1366.698 1.16 15129 15250 2 1366.695693 684.3563 26S proteasome non-ATPase regulatory subunit 6 OS=Homo sapiens OX=9606 GN=PSMD6 PE=1 SV=1 4.09 2963.6 - 1.33E+06 - - - -1.6961 - 2.483 0.519 - 706.6 1 2 0 -0.0023 12 0 0 0 5.41E+07 4.67E+07 - - - 5.2666 0.995 221125_WJC_METTL3_EV_vs_WT_F02.15253.15253.2 0.00286 20-Sep R.MIGGPILPSER[166.11].S "sp|P49419|AL7A1_HUMAN,tr|H0YHM6|H0YHM6_HUMAN,tr|A0A1B0GUA1|A0A1B0GUA1_HUMAN,tr|A0A1B0GTG2|A0A1B0GTG2_HUMAN,tr|A0A1B0GW82|A0A1B0GW82_HUMAN,tr|A0A1B0GV49|A0A1B0GV49_HUMAN,tr|A0A1B0GW77|A0A1B0GW77_HUMAN,tr|A0A1B0GTY9|A0A1B0GTY9_HUMAN,tr|A0A1B0GUY0|A0A1B0GUY0_HUMAN,tr|A0A0J9YWF7|A0A0J9YWF7_HUMAN,tr|A0A1B0GTJ4|A0A1B0GTJ4_HUMAN,tr|F8VVF2|F8VVF2_HUMAN,tr|A0A1B0GVU0|A0A1B0GVU0_HUMAN" 13 1178.6357 1.28 15132 15253 2 1178.631541 590.3251 Alpha-aminoadipic semialdehyde dehydrogenase OS=Homo sapiens OX=9606 GN=ALDH7A1 PE=1 SV=5 5.75 2964 - 713032 - - - -3.5278 - 1.502 0.336 - 209.2 1 2 0 -0.0042 11 0 0 0 3.36E+07 2.63E+07 - - - 2.6219 0.9752 221125_WJC_METTL3_EV_vs_WT_F02.15256.15256.2 0.752 16-Aug R.AGLQFPVGR.V "sp|P16104|H2AX_HUMAN,sp|Q9BTM1|H2AJ_HUMAN,sp|Q93077|H2A1C_HUMAN,sp|Q99878|H2A1J_HUMAN,sp|Q16777|H2A2C_HUMAN,sp|Q8IUE6|H2A2B_HUMAN,sp|Q96QV6|H2A1A_HUMAN,sp|P0C0S5|H2AZ_HUMAN,sp|P04908|H2A1B_HUMAN,sp|P20671|H2A1D_HUMAN,sp|P0C0S8|H2A1_HUMAN,sp|Q6FI13|H2A2A_HUMAN,sp|Q96KK5|H2A1H_HUMAN,sp|Q71UI9|H2AV_HUMAN,sp|Q7L7L0|H2A3_HUMAN,tr|A0A0U1RR32|A0A0U1RR32_HUMAN,tr|A0A0U1RRH7|A0A0U1RRH7_HUMAN,tr|A0A3B3IS11|A0A3B3IS11_HUMAN,tr|C9J0D1|C9J0D1_HUMAN,tr|A0A494C189|A0A494C189_HUMAN" 20 943.524 1.16 15133 15256 2 943.522896 472.7693 Histone H2AX OS=Homo sapiens OX=9606 GN=H2AX PE=1 SV=2 9.79 2964.4 - 5.39E+07 - - - -1.1171 - 1.388 0.042 - 142.4 2 2 0 -0.0011 9 0 0 0 1.35E+10 1.16E+10 - - - 0.1649 1 221125_WJC_METTL3_EV_vs_WT_F02.15257.15257.2 2.20E-08 13/22 R.IFTSIGEDYDER.V "sp|P35232|PHB_HUMAN,tr|C9JZ20|C9JZ20_HUMAN,tr|E7ESE2|E7ESE2_HUMAN,tr|E9PCW0|E9PCW0_HUMAN,tr|C9JW96|C9JW96_HUMAN" 5 1443.6518 1.35 15134 15257 2 1443.649858 722.8332 Prohibitin OS=Homo sapiens OX=9606 GN=PHB PE=1 SV=1 3.92 2964.4 - 7.08E+06 - - - -1.3376 - 2.587 0.619 - 698.7 1 2 0 -0.0019 12 0 0 0 1.66E+08 1.23E+08 - - - 6.1133 0.9983 221125_WJC_METTL3_EV_vs_WT_F02.15262.15262.2 0.068 14-Jul K.APAMFNIR.N "sp|P61247|RS3A_HUMAN,tr|H0Y8L7|H0Y8L7_HUMAN,tr|D6RI02|D6RI02_HUMAN,tr|H0Y9Y4|H0Y9Y4_HUMAN,tr|E9PFI5|E9PFI5_HUMAN,tr|D6RG13|D6RG13_HUMAN" 6 918.4746 0.94 15137 15262 2 918.473644 460.2446 40S ribosomal protein S3a OS=Homo sapiens OX=9606 GN=RPS3A PE=1 SV=2 9.79 2965.1 - 9.76E+06 - - - -0.994 - 1.406 0.27 - 223.6 1 2 0 -0.0009 8 0 0 0 6.80E+08 7.21E+08 - - - 2.0626 0.9988 221125_WJC_METTL3_EV_vs_WT_F02.15264.15264.2 0.031 14-Jul K.LGEFFQTK.Y "sp|Q15029|U5S1_HUMAN,tr|K7EP67|K7EP67_HUMAN" 2 968.4967 1.81 15139 15264 2 968.496185 485.2556 116 kDa U5 small nuclear ribonucleoprotein component OS=Homo sapiens OX=9606 GN=EFTUD2 PE=1 SV=1 6 2965.2 - 2.95E+06 - - - -0.5658 - 1.646 0.234 - 117.9 1 2 0 -0.0005 8 0 0 0 4.13E+08 2.28E+08 - - - 2.2721 0.9559 221125_WJC_METTL3_EV_vs_WT_F02.15265.15265.2 0.00212 20-Oct D.DLGEVLALSLR.A "sp|Q96BJ8|ELMO3_HUMAN,tr|F8W9E7|F8W9E7_HUMAN" 2 1184.6765 999 15140 15265 2 1184.677089 593.3455 Engulfment and cell motility protein 3 OS=Homo sapiens OX=9606 GN=ELMO3 PE=1 SV=3 4.37 2965.3 - 2.72E+06 - - - 0.5073 - 1.789 0.281 - 347.8 1 1 0 0.0006 11 0 0 0 8.68E+07 0.00E+00 - - - 2.6898 0.9981 221125_WJC_METTL3_EV_vs_WT_F02.15266.15266.2 0.0296 14-Aug R.AIEMFMNK[136.11].N "sp|Q13895|BYST_HUMAN,tr|F8WBL2|F8WBL2_HUMAN,tr|H7BY94|H7BY94_HUMAN" 3 990.4758 2.02 15141 15266 2 990.475078 496.2452 Bystin OS=Homo sapiens OX=9606 GN=BYSL PE=1 SV=3 6.05 2965.4 - 985004 - - - -0.738 - 1.435 0.238 - 155.2 1 2 0 -0.0007 8 0 0 0 1.01E+08 5.01E+07 - - - 1.8879 0.9995 221125_WJC_METTL3_EV_vs_WT_F02.15270.15270.2 6.17E-05 18-Nov K.ATGEGFVEFR.N sp|Q9NTZ6|RBM12_HUMAN 1 1111.5298 0.9 15143 15270 2 1111.52697 556.7722 RNA-binding protein 12 OS=Homo sapiens OX=9606 GN=RBM12 PE=1 SV=1 4.53 2965.9 - 2.53E+06 - - - -2.5676 - 1.965 0.477 - 573.7 1 2 0 -0.0029 10 0 0 0 4.73E+07 5.24E+07 - - - 4.4487 0.9962 221125_WJC_METTL3_EV_vs_WT_F02.15272.15272.2 4.05E-07 13/24 K.VVLLTGETSTDLK.L sp|O75643|U520_HUMAN 1 1374.7606 0.61 15145 15272 2 1374.769207 688.3876 U5 small nuclear ribonucleoprotein 200 kDa helicase OS=Homo sapiens OX=9606 GN=SNRNP200 PE=1 SV=2 4.37 2966.1 - 1.33E+06 - - - 6.252 - 2.58 0.564 - 483.2 1 2 0 0.0086 13 0 0 0 2.44E+08 3.98E+08 - - - 5.6365 0.9917 221125_WJC_METTL3_EV_vs_WT_F02.15274.15274.2 0.0248 14-Jul K.FSPADWER[166.11].L "sp|Q6W2J9|BCOR_HUMAN,tr|H7BZ37|H7BZ37_HUMAN,tr|H7C2V9|H7C2V9_HUMAN,tr|H7BYY2|H7BYY2_HUMAN,tr|H7C231|H7C231_HUMAN" 5 1016.4591 1.47 15147 15274 2 1016.455438 509.2368 BCL-6 corepressor OS=Homo sapiens OX=9606 GN=BCOR PE=1 SV=1 4.37 2966.3 - 1.10E+06 - - - -3.6175 - 1.551 0.252 - 179.2 1 2 0 -0.0037 8 0 0 0 1.17E+08 7.98E+07 - - - 2.2248 0.9799 221125_WJC_METTL3_EV_vs_WT_F02.15278.15278.2 0.00819 14-Jul K.LGEFFQTK[136.11].Y "sp|Q15029|U5S1_HUMAN,tr|K7EP67|K7EP67_HUMAN" 2 976.5109 1.81 15149 15278 2 976.508831 489.2627 116 kDa U5 small nuclear ribonucleoprotein component OS=Homo sapiens OX=9606 GN=EFTUD2 PE=1 SV=1 6 2966.8 - 6.59E+06 - - - -2.1526 - 1.336 0.111 - 105.8 1 2 0 -0.0021 8 0 0 0 4.13E+08 2.28E+08 - - - 0.7338 0.9805 221125_WJC_METTL3_EV_vs_WT_F02.15279.15279.2 0.196 14-Jul K.AINTFFAK.N "sp|Q71RC2|LARP4_HUMAN,tr|Q96J85|Q96J85_HUMAN,tr|X6RLN4|X6RLN4_HUMAN" 3 910.4913 1.53 15150 15279 2 910.489864 456.2529 La-related protein 4 OS=Homo sapiens OX=9606 GN=LARP4 PE=1 SV=3 8.8 2966.9 - 4.21E+06 - - - -1.5256 - 1.265 0.098 - 148.8 1 2 0 -0.0014 8 0 0 0 2.73E+08 1.79E+08 - - - 0.4734 0.9993 221125_WJC_METTL3_EV_vs_WT_F02.15282.15282.2 0.000204 18-Oct R.YGSDIVPFSK[136.11].V sp|P13010|XRCC5_HUMAN 1 1119.5692 0.89 15153 15282 2 1119.571339 560.7919 X-ray repair cross-complementing protein 5 OS=Homo sapiens OX=9606 GN=XRCC5 PE=1 SV=3 5.83 2967.2 - 1.48E+06 - - - 1.932 - 1.605 0.438 - 200.7 1 2 0 0.0022 10 0 0 0 1.65E+08 1.85E+08 - - - 3.596 0.9993 221125_WJC_METTL3_EV_vs_WT_F02.15283.15283.2 0.00284 14-Jul R.DVPLPVVR.V "sp|Q86U86|PB1_HUMAN,tr|H0Y5B5|H0Y5B5_HUMAN,tr|E7EVG2|E7EVG2_HUMAN" 3 893.5335 1.69 15154 15283 2 893.533906 447.774 Protein polybromo-1 OS=Homo sapiens OX=9606 GN=PBRM1 PE=1 SV=1 5.84 2967.3 - 1.04E+06 - - - 0.5081 - 1.357 0.381 - 192.9 1 2 0 0.0005 8 0 0 0 1.68E+08 9.90E+07 - - - 2.7756 0.9993 221125_WJC_METTL3_EV_vs_WT_F02.15284.15284.2 0.0118 18-Oct K.ITMIAEPLEK.G "sp|Q15029|U5S1_HUMAN,tr|K7EP67|K7EP67_HUMAN" 2 1143.6209 2.28 15155 15284 2 1143.622777 572.8177 116 kDa U5 small nuclear ribonucleoprotein component OS=Homo sapiens OX=9606 GN=EFTUD2 PE=1 SV=1 4.53 2967.4 - 2.36E+06 - - - 1.6002 - 1.957 0.329 - 295.5 1 2 0 0.0018 10 0 0 0 4.05E+08 1.78E+08 - - - 3.3445 0.988 221125_WJC_METTL3_EV_vs_WT_F02.15287.15287.2 0.16 18-Nov K.AIQLNPSYIR.A "sp|Q99614|TTC1_HUMAN,tr|A0A804HKC5|A0A804HKC5_HUMAN,tr|H0YB37|H0YB37_HUMAN,tr|A0A804HIB8|A0A804HIB8_HUMAN" 4 1173.6506 0.94 15156 15287 2 1173.645059 587.8326 Tetratricopeptide repeat protein 1 OS=Homo sapiens OX=9606 GN=TTC1 PE=1 SV=1 8.79 2967.8 - 2.30E+06 - - - -4.7271 - 2.113 0.201 - 463 1 2 0 -0.0055 10 0 0 0 8.65E+07 9.17E+07 - - - 2.612 0.9956 221125_WJC_METTL3_EV_vs_WT_F02.15291.15291.2 0.0153 18-Oct K.ITMIAEPLEK[136.11].G "sp|Q15029|U5S1_HUMAN,tr|K7EP67|K7EP67_HUMAN" 2 1151.6351 2.28 15158 15291 2 1151.632799 576.8248 116 kDa U5 small nuclear ribonucleoprotein component OS=Homo sapiens OX=9606 GN=EFTUD2 PE=1 SV=1 4.53 2968.3 - 3.15E+06 - - - -2.0388 - 1.653 0.184 - 303.5 1 2 0 -0.0023 10 0 0 0 4.05E+08 1.78E+08 - - - 1.8022 0.9969 221125_WJC_METTL3_EV_vs_WT_F02.15292.15292.2 0.0133 18-Sep K.EPLVDVVDPK.Q "sp|Q99873|ANM1_HUMAN,tr|E9PQ98|E9PQ98_HUMAN,tr|E9PKG1|E9PKG1_HUMAN,tr|E9PIX6|E9PIX6_HUMAN" 4 1109.5968 2.23 15159 15292 2 1109.594735 555.8057 Protein arginine N-methyltransferase 1 OS=Homo sapiens OX=9606 GN=PRMT1 PE=1 SV=3 4.03 2968.3 - 1.71E+06 - - - -1.898 - 1.478 0.254 - 236.6 1 2 0 -0.0021 10 0 0 0 2.16E+08 9.68E+07 - - - 2.0069 1 221125_WJC_METTL3_EV_vs_WT_F02.15293.15293.2 6.38E-06 18-Nov K.AFMVTDEDIR.K "sp|O95983|MBD3_HUMAN,tr|K7EIE8|K7EIE8_HUMAN" 2 1195.5543 1.53 15160 15293 2 1195.553139 598.7844 Methyl-CpG-binding domain protein 3 OS=Homo sapiens OX=9606 GN=MBD3 PE=1 SV=1 4.03 2968.4 - 3.83E+06 - - - -0.9912 - 2.466 0.61 - 611.7 1 2 0 -0.0012 10 0 0 0 5.50E+08 3.60E+08 - - - 6.0655 0.9918 221125_WJC_METTL3_EV_vs_WT_F02.15295.15295.2 0.0005 14-Jul K.MFYSFQDK[136.11].R "sp|Q9Y2H1|ST38L_HUMAN,sp|Q15208|STK38_HUMAN,tr|F5H277|F5H277_HUMAN" 3 1072.4779 3.45 15162 15295 2 1072.473634 537.2462 Serine\threonine-protein kinase 38-like OS=Homo sapiens OX=9606 GN=STK38L PE=1 SV=3 5.59 2968.6 - 3.38E+06 - - - -3.9945 - 1.349 0.343 - 190.3 1 2 0 -0.0043 8 0 0 0 2.54E+08 7.37E+07 - - - 2.4759 0.9996 221125_WJC_METTL3_EV_vs_WT_F02.15297.15297.2 0.0447 18-Oct R.ILSC[160.03]GELIPK.S "sp|Q13427|PPIG_HUMAN,tr|A0A7I2V629|A0A7I2V629_HUMAN,tr|C9JM79|C9JM79_HUMAN,tr|E9PG73|E9PG73_HUMAN,tr|C9JN15|C9JN15_HUMAN,tr|A0A7I2V4F2|A0A7I2V4F2_HUMAN,tr|A0A7I2V5Q5|A0A7I2V5Q5_HUMAN" 7 1128.6213 1.26 15164 15297 2 1128.620252 565.3179 Peptidyl-prolyl cis-trans isomerase G OS=Homo sapiens OX=9606 GN=PPIG PE=1 SV=2 5.99 2968.8 - 1.50E+06 - - - -0.9117 - 1.957 0.35 - 190 1 2 0 -0.001 10 0 0 0 5.82E+07 4.61E+07 - - - 3.4999 0.9994 221125_WJC_METTL3_EV_vs_WT_F02.15302.15302.2 0.128 14-Aug K.APAMFNIR[166.11].N "sp|P61247|RS3A_HUMAN,tr|H0Y8L7|H0Y8L7_HUMAN,tr|D6RI02|D6RI02_HUMAN,tr|H0Y9Y4|H0Y9Y4_HUMAN,tr|E9PFI5|E9PFI5_HUMAN,tr|D6RG13|D6RG13_HUMAN" 6 928.4828 0.94 15167 15302 2 928.482081 465.2487 40S ribosomal protein S3a OS=Homo sapiens OX=9606 GN=RPS3A PE=1 SV=2 9.79 2969.3 - 1.82E+07 - - - -0.8035 - 1.79 0.285 - 250.8 1 2 0 -0.0007 8 0 0 0 6.77E+08 7.20E+08 - - - 2.9017 0.9986 221125_WJC_METTL3_EV_vs_WT_F02.15303.15303.2 0.0463 14-Aug R.DVPLPVVR[166.11].V "sp|Q86U86|PB1_HUMAN,tr|H0Y5B5|H0Y5B5_HUMAN,tr|E7EVG2|E7EVG2_HUMAN" 3 903.5417 1.67 15168 15303 2 903.540899 452.7781 Protein polybromo-1 OS=Homo sapiens OX=9606 GN=PBRM1 PE=1 SV=1 5.84 2969.4 - 1.21E+06 - - - -0.9109 - 1.504 0.264 - 265.2 1 2 0 -0.0008 8 0 0 0 1.66E+08 9.90E+07 - - - 2.2215 0.9996 221125_WJC_METTL3_EV_vs_WT_F02.15305.15305.2 1.18E-07 18-Nov R.YGSDIVPFSK.V sp|P13010|XRCC5_HUMAN 1 1111.555 0.88 15170 15305 2 1111.55169 556.7848 X-ray repair cross-complementing protein 5 OS=Homo sapiens OX=9606 GN=XRCC5 PE=1 SV=3 5.83 2969.5 - 2.61E+06 - - - -2.9562 - 2.122 0.563 - 325.9 1 2 0 -0.0033 10 0 0 0 1.66E+08 1.89E+08 - - - 5.2983 0.9998 221125_WJC_METTL3_EV_vs_WT_F02.15307.15307.2 0.002 14/20 R.IEIVVVGTGDR.T sp|Q9BU61|NDUF3_HUMAN 1 1156.6452 0.47 15172 15307 2 1156.643981 579.3299 NADH dehydrogenase [ubiquinone] 1 alpha subcomplex assembly factor 3 OS=Homo sapiens OX=9606 GN=NDUFAF3 PE=1 SV=1 4.37 2969.8 - 1.01E+06 - - - -1.0435 - 2.551 0.399 - 715.6 1 2 0 -0.0012 11 0 0 0 7.93E+07 1.70E+08 - - - 4.521 0.9803 221125_WJC_METTL3_EV_vs_WT_F02.15311.15311.2 0.032 16-Jul R.IDISPSTFR.K "sp|Q9Y2W1|TR150_HUMAN,tr|A0A3B3ITZ9|A0A3B3ITZ9_HUMAN" 2 1034.5397 2.54 15174 15311 2 1034.535613 518.2771 Thyroid hormone receptor-associated protein 3 OS=Homo sapiens OX=9606 GN=THRAP3 PE=1 SV=2 5.84 2970.3 - 2.58E+08 - - - -3.9119 - 1.372 0.234 - 86.5 1 2 0 -0.004 9 0 0 0 5.31E+09 2.09E+09 - - - 1.683 1 221125_WJC_METTL3_EV_vs_WT_F02.15312.15312.2 4.43E-05 14/24 K.VVLLTGETSTDLK[136.11].L sp|O75643|U520_HUMAN 1 1382.7748 0.52 15175 15312 2 1382.774487 692.3947 U5 small nuclear ribonucleoprotein 200 kDa helicase OS=Homo sapiens OX=9606 GN=SNRNP200 PE=1 SV=2 4.37 2970.4 - 7.57E+06 - - - -0.235 - 2.653 0.586 - 630.2 1 2 0 -0.0003 13 0 0 0 2.44E+08 4.68E+08 - - - 5.8732 0.933 221125_WJC_METTL3_EV_vs_WT_F02.15319.15319.2 19.3 12-Aug R.QSILILK.E "sp|P33240|CSTF2_HUMAN,sp|Q9H0L4|CSTFT_HUMAN,tr|E7EWR4|E7EWR4_HUMAN" 3 813.5324 2.53 15180 15319 2 813.530997 407.7735 Cleavage stimulation factor subunit 2 OS=Homo sapiens OX=9606 GN=CSTF2 PE=1 SV=1 8.75 2971.2 - 1.59E+06 - - - -1.7123 - 1.233 0.003 - 167.4 1 2 0 -0.0014 7 0 0 0 2.95E+08 1.17E+08 - - - -0.2736 0.9884 221125_WJC_METTL3_EV_vs_WT_F02.15321.15321.2 2.61 14-Jun K.FSPADWER.L "sp|Q6W2J9|BCOR_HUMAN,tr|H7BZ37|H7BZ37_HUMAN,tr|H7C2V9|H7C2V9_HUMAN,tr|H7BYY2|H7BYY2_HUMAN,tr|H7C231|H7C231_HUMAN" 5 1006.4508 1.35 15181 15321 2 1006.450075 504.2327 BCL-6 corepressor OS=Homo sapiens OX=9606 GN=BCOR PE=1 SV=1 4.37 2971.4 - 2.38E+06 - - - -0.7651 - 1.142 0.154 - 127.9 1 2 0 -0.0008 8 0 0 0 1.19E+08 8.80E+07 - - - 0.5787 0.9998 221125_WJC_METTL3_EV_vs_WT_F02.15323.15323.2 9.15E-05 13/24 K.FLADQQSEIDGLK.G "sp|P12270|TPR_HUMAN,tr|Q5SWX9|Q5SWX9_HUMAN" 2 1462.7304 3.11 15183 15323 2 1462.732932 732.3725 Nucleoprotein TPR OS=Homo sapiens OX=9606 GN=TPR PE=1 SV=3 4.03 2971.7 - 1.23E+06 - - - 1.7488 - 2.4 0.514 - 433.8 1 2 0 0.0026 13 0 0 0 1.60E+08 5.14E+07 - - - 5.0835 0.9201 221125_WJC_METTL3_EV_vs_WT_F02.15324.15324.2 8.96 12-Jul R.QSILILK[136.11].E "sp|P33240|CSTF2_HUMAN,sp|Q9H0L4|CSTFT_HUMAN,tr|E7EWR4|E7EWR4_HUMAN" 3 821.5466 2.53 15184 15324 2 821.54491 411.7806 Cleavage stimulation factor subunit 2 OS=Homo sapiens OX=9606 GN=CSTF2 PE=1 SV=1 8.75 2971.8 - 1.05E+06 - - - -2.0449 - 1.245 0.002 - 148.5 1 2 0 -0.0017 7 0 0 0 2.95E+08 1.17E+08 - - - -0.2504 1 221125_WJC_METTL3_EV_vs_WT_F02.15330.15330.3 9.50E-08 14/48 R.LVHPGVAEVVFVK[136.11].K "sp|Q9BY77|PDIP3_HUMAN,tr|F6VRR5|F6VRR5_HUMAN" 2 1400.8271 1.38 15188 15330 3 1400.826457 467.9497 Polymerase delta-interacting protein 3 OS=Homo sapiens OX=9606 GN=POLDIP3 PE=1 SV=2 6.75 2972.5 - 1.89E+07 - - - -0.4747 - 2.717 0.55 - 368.2 1 2 0 -0.0007 13 0 0 0 2.45E+09 1.78E+09 - - - 7.3818 0.9999 221125_WJC_METTL3_EV_vs_WT_F02.15331.15331.2 3.56E-05 17/24 R.LVHPGVAEVVFVK.K "sp|Q9BY77|PDIP3_HUMAN,tr|F6VRR5|F6VRR5_HUMAN" 2 1392.8129 1.35 15189 15331 2 1392.810748 697.4137 Polymerase delta-interacting protein 3 OS=Homo sapiens OX=9606 GN=POLDIP3 PE=1 SV=2 6.75 2972.6 - 7.19E+06 - - - -1.5609 - 2.761 0.534 - 669.8 1 2 0 -0.0022 13 0 0 0 2.95E+08 2.18E+08 - - - 5.591 0.9994 221125_WJC_METTL3_EV_vs_WT_F02.15332.15332.2 0.04 20-Oct R.IEIVVVGTGDR[166.11].T sp|Q9BU61|NDUF3_HUMAN 1 1166.6535 0.44 15190 15332 2 1166.652093 584.334 NADH dehydrogenase [ubiquinone] 1 alpha subcomplex assembly factor 3 OS=Homo sapiens OX=9606 GN=NDUFAF3 PE=1 SV=1 4.37 2972.6 - 1.33E+07 - - - -1.17 - 2.198 0.272 - 182.3 1 2 0 -0.0014 11 0 0 0 8.00E+07 1.83E+08 - - - 3.1801 0.9997 221125_WJC_METTL3_EV_vs_WT_F02.15333.15333.2 0.000142 14/20 K.TLLNSQLEMER[166.11].M "sp|P82094|TMF1_HUMAN,tr|A0A2R8Y7M0|A0A2R8Y7M0_HUMAN" 2 1342.679 1.56 15191 15333 2 1342.675681 672.3468 TATA element modulatory factor OS=Homo sapiens OX=9606 GN=TMF1 PE=1 SV=2 4.53 2972.8 - 1.97E+06 - - - -2.4876 - 2.591 0.534 - 598.2 1 2 0 -0.0033 11 0 0 0 1.47E+08 9.42E+07 - - - 5.5596 0.9698 221125_WJC_METTL3_EV_vs_WT_F02.15335.15335.2 5.79 12-May R.LELFTSR.F "sp|Q9UJ98|STAG3_HUMAN,sp|Q8N3U4|STAG2_HUMAN,tr|D6W5U7|D6W5U7_HUMAN,tr|B1AMT4|B1AMT4_HUMAN" 4 864.4705 1.13 15193 15335 2 864.468608 433.2425 Cohesin subunit SA-3 OS=Homo sapiens OX=9606 GN=STAG3 PE=1 SV=2 6 2973 - 738958 - - - -2.2094 - 1.075 0.164 - 77.8 1 2 0 -0.0019 7 0 0 0 1.51E+07 1.34E+07 - - - 0.4809 0.9998 221125_WJC_METTL3_EV_vs_WT_F02.15337.15337.2 5.32E-05 16-Sep R.VLDELTLTK.A "sp|P13645|K1C10_HUMAN,tr|A0A1B0GVI3|A0A1B0GVI3_HUMAN" 2 1030.591 486.7 15194 15337 2 1030.590442 516.3028 "Keratin, type I cytoskeletal 10 OS=Homo sapiens OX=9606 GN=KRT10 PE=1 SV=6" 4.37 2973.2 - 6.67E+08 - - - -0.5676 - 2 0.472 - 265.7 1 2 0 -0.0006 9 0 0 0 3.52E+10 7.23E+07 - - - 4.5323 1 221125_WJC_METTL3_EV_vs_WT_F02.15339.15339.3 1.06E-07 Dec-48 R.LVHPGVAEVVFVK.K "sp|Q9BY77|PDIP3_HUMAN,tr|F6VRR5|F6VRR5_HUMAN" 2 1392.8129 1.38 15195 15339 3 1392.811834 465.2783 Polymerase delta-interacting protein 3 OS=Homo sapiens OX=9606 GN=POLDIP3 PE=1 SV=2 6.75 2973.4 - 2.91E+07 - - - -0.7812 - 2.474 0.533 - 245.8 1 2 0 -0.0011 13 0 0 0 2.45E+09 1.78E+09 - - - 6.9381 0.9997 221125_WJC_METTL3_EV_vs_WT_F02.15340.15340.2 0.00114 16-Sep R.SPIAEAVFR[166.11].K "sp|P24666|PPAC_HUMAN,tr|D3YTI2|D3YTI2_HUMAN,tr|F2Z2Q9|F2Z2Q9_HUMAN,tr|G5E9R5|G5E9R5_HUMAN" 4 998.5425 1.05 15196 15340 2 998.54077 500.2785 Low molecular weight phosphotyrosine protein phosphatase OS=Homo sapiens OX=9606 GN=ACP1 PE=1 SV=3 5.72 2973.4 - 4.04E+06 - - - -1.6835 - 1.882 0.483 - 258.9 1 2 0 -0.0017 9 0 0 0 5.08E+08 4.84E+08 - - - 4.4373 0.9999 221125_WJC_METTL3_EV_vs_WT_F02.15342.15342.2 0.0304 14/24 K.FLADQQSEIDGLK[136.11].G "sp|P12270|TPR_HUMAN,tr|Q5SWX9|Q5SWX9_HUMAN" 2 1470.7446 3.15 15198 15342 2 1470.743695 736.3796 Nucleoprotein TPR OS=Homo sapiens OX=9606 GN=TPR PE=1 SV=3 4.03 2973.6 - 1.38E+06 - - - -0.5977 - 2.486 0.446 - 522.6 1 2 0 -0.0009 13 0 0 0 1.60E+08 5.09E+07 - - - 4.6722 0.9876 221125_WJC_METTL3_EV_vs_WT_F02.15346.15346.2 0.000181 16-Jul R.PLPSFC[160.03]PPR.R sp|Q5T749|KPRP_HUMAN 1 1069.5379 227.45 15200 15346 2 1069.537016 535.7762 Keratinocyte proline-rich protein OS=Homo sapiens OX=9606 GN=KPRP PE=1 SV=1 8.68 2974.1 - 6.97E+06 - - - -0.8134 - 1.546 0.524 - 200.3 1 1 0 -0.0009 9 0 0 0 3.82E+08 1.68E+06 - - - 4.1714 0.9994 221125_WJC_METTL3_EV_vs_WT_F02.15347.15347.2 0.000109 12-Jul R.LYFC[160.03]VDR[166.11].G "sp|O14654|IRS4_HUMAN,tr|A0A804CF45|A0A804CF45_HUMAN" 2 981.4618 0.71 15201 15347 2 981.460361 491.7382 Insulin receptor substrate 4 OS=Homo sapiens OX=9606 GN=IRS4 PE=1 SV=1 5.83 2974.2 - 5.06E+06 - - - -1.4234 - 1.328 0.44 - 220.5 1 2 0 -0.0014 7 0 0 0 1.12E+08 1.57E+08 - - - 3.1892 0.9996 221125_WJC_METTL3_EV_vs_WT_F02.15348.15348.2 0.000475 14-Aug K.MFYSFQDK.R "sp|Q9Y2H1|ST38L_HUMAN,sp|Q15208|STK38_HUMAN,tr|F5H277|F5H277_HUMAN" 3 1064.4637 3.45 15202 15348 2 1064.462477 533.2391 Serine\threonine-protein kinase 38-like OS=Homo sapiens OX=9606 GN=STK38L PE=1 SV=3 5.59 2974.2 - 6.84E+06 - - - -1.1658 - 1.229 0.536 - 191.7 1 2 0 -0.0012 8 0 0 0 2.54E+08 7.37E+07 - - - 3.6214 0.9966 221125_WJC_METTL3_EV_vs_WT_F02.15349.15349.2 0.00438 16-Aug R.SPIAEAVFR.K "sp|P24666|PPAC_HUMAN,tr|D3YTI2|D3YTI2_HUMAN,tr|F2Z2Q9|F2Z2Q9_HUMAN,tr|G5E9R5|G5E9R5_HUMAN" 4 988.5342 1.05 15203 15349 2 988.531588 495.2744 Low molecular weight phosphotyrosine protein phosphatase OS=Homo sapiens OX=9606 GN=ACP1 PE=1 SV=3 5.72 2974.3 - 5.32E+06 - - - -2.6231 - 1.612 0.263 - 247.6 1 2 0 -0.0026 9 0 0 0 5.08E+08 4.84E+08 - - - 2.3641 0.9998 221125_WJC_METTL3_EV_vs_WT_F02.15350.15350.2 3.21E-05 16-Oct K.SPFEVYVDK.S "sp|P21333|FLNA_HUMAN,tr|A0A7P0NMY4|A0A7P0NMY4_HUMAN,tr|Q60FE5|Q60FE5_HUMAN,tr|A0A7I2V3E6|A0A7I2V3E6_HUMAN,tr|A0A087WWY3|A0A087WWY3_HUMAN,tr|F8WE98|F8WE98_HUMAN" 6 1082.5284 0.89 15204 15350 2 1082.527092 542.2715 Filamin-A OS=Homo sapiens OX=9606 GN=FLNA PE=1 SV=4 4.37 2974.3 - 2.33E+06 - - - -1.2332 - 2.035 0.494 - 381.7 1 2 0 -0.0013 9 0 0 0 1.01E+08 1.13E+08 - - - 4.7448 0.9968 221125_WJC_METTL3_EV_vs_WT_F02.15355.15355.2 0.506 14-Jul K.NFNETFLK[136.11].R "sp|Q9BXJ9|NAA15_HUMAN,tr|A0A0B4J1W3|A0A0B4J1W3_HUMAN" 2 1019.5167 0.25 15207 15355 2 1019.516292 510.7656 "N-alpha-acetyltransferase 15, NatA auxiliary subunit OS=Homo sapiens OX=9606 GN=NAA15 PE=1 SV=1" 6 2975 - 1.94E+06 - - - -0.4453 - 1.295 0.221 - 163.3 1 2 0 -0.0005 8 0 0 0 1.18E+07 4.67E+07 - - - 1.4528 0.9999 221125_WJC_METTL3_EV_vs_WT_F02.15357.15357.2 6.29E-06 24-Dec R.LVHPGVAEVVFVK[136.11].K "sp|Q9BY77|PDIP3_HUMAN,tr|F6VRR5|F6VRR5_HUMAN" 2 1400.8271 1.36 15209 15357 2 1400.826122 701.4208 Polymerase delta-interacting protein 3 OS=Homo sapiens OX=9606 GN=POLDIP3 PE=1 SV=2 6.75 2975.1 - 5.93E+06 - - - -0.7139 - 2.375 0.497 - 353 1 2 0 -0.001 13 0 0 0 2.95E+08 2.18E+08 - - - 4.9316 0.925 221125_WJC_METTL3_EV_vs_WT_F02.15362.15362.2 3.69 14-Oct R.R[166.11]VPFSLLR[166.11].G "sp|P04792|HSPB1_HUMAN,tr|A0A6Q8PGY2|A0A6Q8PGY2_HUMAN,tr|A0A6Q8PHJ6|A0A6Q8PHJ6_HUMAN,tr|A0A6Q8PHA6|A0A6Q8PHA6_HUMAN,tr|A0A6Q8PF43|A0A6Q8PF43_HUMAN,tr|A0A6Q8PFK8|A0A6Q8PFK8_HUMAN,tr|A0A6Q8PGK1|A0A6Q8PGK1_HUMAN,tr|A0A6Q8PH65|A0A6Q8PH65_HUMAN,tr|A0A6Q8PFE7|A0A6Q8PFE7_HUMAN" 9 1006.6191 1.98 15211 15362 2 1006.616123 504.3168 Heat shock protein beta-1 OS=Homo sapiens OX=9606 GN=HSPB1 PE=1 SV=2 12 2975.8 - 3.21E+06 - - - -2.9326 - 1.039 0.142 - 270 1 2 0 -0.003 8 0 0 0 1.60E+08 8.09E+07 - - - 0.2043 0.9735 221125_WJC_METTL3_EV_vs_WT_F02.15363.15363.2 1.25 18-Jul K.ISSALSVLGK.V "sp|Q86UP3|ZFHX4_HUMAN,tr|E7EVZ1|E7EVZ1_HUMAN" 2 973.5808 0.46 15212 15363 2 973.580627 487.7977 Zinc finger homeobox protein 4 OS=Homo sapiens OX=9606 GN=ZFHX4 PE=1 SV=1 8.75 2975.9 - 3.33E+06 - - - -0.1746 - 1.002 0.125 - 66.6 1 2 0 -0.0002 10 0 0 0 2.69E+07 5.87E+07 - - - -0.0302 0.9991 221125_WJC_METTL3_EV_vs_WT_F02.15364.15364.2 0.021 12-Jul R.LYFC[160.03]VDR.G "sp|O14654|IRS4_HUMAN,tr|A0A804CF45|A0A804CF45_HUMAN" 2 971.4535 0.72 15213 15364 2 971.451419 486.734 Insulin receptor substrate 4 OS=Homo sapiens OX=9606 GN=IRS4 PE=1 SV=1 5.83 2975.9 - 5.51E+06 - - - -2.1298 - 1.603 0.372 - 181 1 2 0 -0.0021 7 0 0 0 1.12E+08 1.55E+08 - - - 3.2831 0.9797 221125_WJC_METTL3_EV_vs_WT_F02.15365.15365.2 0.0132 12-Jun V.AEVVFVK.K "sp|Q9BY77|PDIP3_HUMAN,tr|F6VRR5|F6VRR5_HUMAN" 2 790.4589 0.61 15214 15365 2 790.458271 396.2367 Polymerase delta-interacting protein 3 OS=Homo sapiens OX=9606 GN=POLDIP3 PE=1 SV=2 6.05 2976.1 - 399415 - - - -0.7831 - 1.469 0.443 - 169 1 1 0 -0.0006 7 0 0 0 5.39E+06 8.90E+06 - - - 3.5314 0.9998 221125_WJC_METTL3_EV_vs_WT_F02.15368.15368.2 7.92E-07 18-Oct K.AFMVTDEDIR[166.11].K "sp|O95983|MBD3_HUMAN,tr|K7EIE8|K7EIE8_HUMAN" 2 1205.5626 1.53 15215 15368 2 1205.560711 603.7886 Methyl-CpG-binding domain protein 3 OS=Homo sapiens OX=9606 GN=MBD3 PE=1 SV=1 4.03 2976.4 - 8.26E+06 - - - -1.5619 - 2.082 0.546 - 515.7 1 2 0 -0.0019 10 0 0 0 5.50E+08 3.60E+08 - - - 5.1201 0.9689 221125_WJC_METTL3_EV_vs_WT_F02.15369.15369.2 1.52 14-Jul K.TISQLFAK.N "sp|Q4VCS5|AMOT_HUMAN,tr|A6NP16|A6NP16_HUMAN,tr|E7ERM3|E7ERM3_HUMAN" 3 906.5175 1.68 15216 15369 2 906.51583 454.266 Angiomotin OS=Homo sapiens OX=9606 GN=AMOT PE=1 SV=1 8.41 2976.5 - 3.52E+06 - - - -1.8069 - 1.08 0.136 - 118.5 1 2 0 -0.0016 8 0 0 0 1.22E+08 7.30E+07 - - - 0.2771 0.981 221125_WJC_METTL3_EV_vs_WT_F02.15375.15375.2 0.771 16-Aug R.LSAFGQIYK.V sp|Q96SI9|STRBP_HUMAN 1 1025.5546 1.38 15220 15375 2 1025.5515 513.7846 Spermatid perinuclear RNA-binding protein OS=Homo sapiens OX=9606 GN=STRBP PE=1 SV=1 8.59 2977.2 - 1.73E+06 - - - -3.0052 - 1.736 0.078 - 134.5 1 2 0 -0.0031 9 0 0 0 5.11E+07 3.70E+07 - - - 1.2119 0.7999 221125_WJC_METTL3_EV_vs_WT_F02.15383.15383.2 0.000534 20-Oct K.VFDGIPPPYDK.K "sp|P40429|RL13A_HUMAN,sp|Q6NVV1|R13P3_HUMAN,tr|M0QYS1|M0QYS1_HUMAN,tr|Q8J015|Q8J015_HUMAN,tr|A0A7I2V2L9|A0A7I2V2L9_HUMAN,tr|A0A7I2V5L3|A0A7I2V5L3_HUMAN" 6 1246.6234 1.45 15226 15383 2 1247.622375 624.319 60S ribosomal protein L13a OS=Homo sapiens OX=9606 GN=RPL13A PE=1 SV=2 4.21 2978.3 - 2.47E+06 - - - 801.3527 - 1.611 0.326 - 282 1 2 0 0.999 11 0 0 0 5.32E+07 3.67E+07 - - - 2.4252 0.9932 221125_WJC_METTL3_EV_vs_WT_F02.15385.15385.2 0.435 12-Aug R.SPNLWLK[136.11].D sp|P78527|PRKDC_HUMAN 1 864.4949 0.84 15228 15385 2 864.494811 433.2547 DNA-dependent protein kinase catalytic subunit OS=Homo sapiens OX=9606 GN=PRKDC PE=1 SV=3 8.47 2978.5 - 696054 - - - -0.0902 - 1.29 0.14 - 166.7 1 2 0 -0.0001 7 0 0 0 7.60E+06 9.04E+06 - - - 0.8819 0.9987 221125_WJC_METTL3_EV_vs_WT_F02.15388.15388.2 6.18E-05 16-Sep R.QIFNGTFVK[136.11].L "sp|P18124|RL7_HUMAN,tr|C9JIJ5|C9JIJ5_HUMAN,tr|C9JZ88|C9JZ88_HUMAN,tr|A8MUD9|A8MUD9_HUMAN" 4 1060.5797 1.18 15229 15388 2 1060.577183 531.2971 60S ribosomal protein L7 OS=Homo sapiens OX=9606 GN=RPL7 PE=1 SV=1 8.75 2978.9 - 2.55E+06 - - - -2.3553 - 1.63 0.356 - 260.8 1 2 0 -0.0025 9 0 0 0 1.32E+08 1.12E+08 - - - 3.0831 0.9994 221125_WJC_METTL3_EV_vs_WT_F02.15389.15389.2 0.00342 18-Sep K.EPLVDVVDPK[136.11].Q "sp|Q99873|ANM1_HUMAN,tr|E9PQ98|E9PQ98_HUMAN,tr|E9PKG1|E9PKG1_HUMAN,tr|E9PIX6|E9PIX6_HUMAN" 4 1117.611 2.22 15230 15389 2 1117.611075 559.8128 Protein arginine N-methyltransferase 1 OS=Homo sapiens OX=9606 GN=PRMT1 PE=1 SV=3 4.03 2979 - 2.31E+06 - - - 0.0304 - 1.635 0.332 - 221.1 1 2 0 0 10 0 0 0 2.14E+08 9.66E+07 - - - 2.8655 0.9549 221125_WJC_METTL3_EV_vs_WT_F02.15390.15390.2 1.73 12-Jun R.DIEQIIR[166.11].N sp|O15226|NKRF_HUMAN 1 895.5003 0.95 15231 15390 2 895.49924 448.7574 NF-kappa-B-repressing factor OS=Homo sapiens OX=9606 GN=NKRF PE=1 SV=2 4.37 2979 - 4.10E+06 - - - -1.1301 - 1.259 0.001 - 147.4 1 2 0 -0.001 7 0 0 0 7.00E+07 7.37E+07 - - - -0.2222 0.9846 221125_WJC_METTL3_EV_vs_WT_F02.15392.15392.2 0.0789 16-Sep R.VPPEFLVQR.A "sp|Q13724|MOGS_HUMAN,tr|A0A3B3IRK6|A0A3B3IRK6_HUMAN,tr|A0A3B3IRW2|A0A3B3IRW2_HUMAN" 3 1083.6077 0.94 15233 15392 2 1083.603761 542.8111 Mannosyl-oligosaccharide glucosidase OS=Homo sapiens OX=9606 GN=MOGS PE=1 SV=5 5.97 2979.3 - 985162 - - - -3.6166 - 1.407 0.228 - 172.4 1 2 0 -0.0039 9 0 0 0 7.15E+07 7.60E+07 - - - 1.7116 0.9997 221125_WJC_METTL3_EV_vs_WT_F02.15394.15394.2 2.75E-05 13/20 K.LVQEALEAVPR.G "sp|Q15269|PWP2_HUMAN,tr|A0A0B4J2E5|A0A0B4J2E5_HUMAN" 2 1223.6874 1.16 15235 15394 2 1223.689686 612.851 Periodic tryptophan protein 2 homolog OS=Homo sapiens OX=9606 GN=PWP2 PE=2 SV=2 4.53 2979.5 - 738413 - - - 1.8787 - 2.327 0.479 - 722.2 1 2 0 0.0023 11 0 0 0 6.02E+07 5.17E+07 - - - 4.863 0.9998 221125_WJC_METTL3_EV_vs_WT_F02.15395.15395.2 0.00436 20-Dec K.LVQEALEAVPR[166.11].G "sp|Q15269|PWP2_HUMAN,tr|A0A0B4J2E5|A0A0B4J2E5_HUMAN" 2 1233.6957 1.16 15236 15395 2 1233.694845 617.8551 Periodic tryptophan protein 2 homolog OS=Homo sapiens OX=9606 GN=PWP2 PE=2 SV=2 4.53 2979.6 - 733083 - - - -0.6582 - 2.286 0.402 - 228.3 1 2 0 -0.0008 11 0 0 0 6.02E+07 5.17E+07 - - - 4.2466 1 221125_WJC_METTL3_EV_vs_WT_F02.15396.15396.2 3.54E-09 16/28 K.NQVALNPQNTVFDAK[136.11].R "sp|P0DMV8|HS71A_HUMAN,sp|P0DMV9|HS71B_HUMAN,tr|A0A0G2JIW1|A0A0G2JIW1_HUMAN" 3 1665.8566 0.08 15237 15396 2 1665.853425 833.9356 Heat shock 70 kDa protein 1A OS=Homo sapiens OX=9606 GN=HSPA1A PE=1 SV=1 5.84 2979.8 - 423455 - - - -1.8963 - 3.014 0.668 - 622.2 1 2 0 -0.0032 15 0 0 0 1.92E+06 2.44E+07 - - - 6.6863 0.992 221125_WJC_METTL3_EV_vs_WT_F02.15400.15400.2 0.0748 16-Aug R.QIFNGTFVK.L "sp|P18124|RL7_HUMAN,tr|C9JIJ5|C9JIJ5_HUMAN,tr|C9JZ88|C9JZ88_HUMAN,tr|A8MUD9|A8MUD9_HUMAN" 4 1052.5655 1.14 15239 15400 2 1052.563673 527.29 60S ribosomal protein L7 OS=Homo sapiens OX=9606 GN=RPL7 PE=1 SV=1 8.75 2980.2 - 5.62E+06 - - - -1.7177 - 1.432 0.149 - 180.6 1 2 0 -0.0018 9 0 0 0 1.26E+08 1.11E+08 - - - 1.1798 0.9245 221125_WJC_METTL3_EV_vs_WT_F02.15402.15402.2 5.53 12-Jun R.DIEQIIR.N sp|O15226|NKRF_HUMAN 1 885.492 0.95 15241 15402 2 885.490305 443.7533 NF-kappa-B-repressing factor OS=Homo sapiens OX=9606 GN=NKRF PE=1 SV=2 4.37 2980.3 - 6.02E+06 - - - -1.8939 - 1.237 0.001 - 140 1 2 0 -0.0017 7 0 0 0 7.00E+07 7.37E+07 - - - -0.2782 0.995 221125_WJC_METTL3_EV_vs_WT_F02.15403.15403.2 0.276 16-Aug R.TDPIPIVVK.Y "sp|Q9UKJ3|GPTC8_HUMAN,tr|K7EKU0|K7EKU0_HUMAN" 2 980.5906 0.87 15242 15403 2 980.589512 491.3026 G patch domain-containing protein 8 OS=Homo sapiens OX=9606 GN=GPATCH8 PE=1 SV=2 5.5 2980.4 - 2.84E+06 - - - -1.1432 - 1.172 0.241 - 185.8 1 2 0 -0.0011 9 0 0 0 9.45E+07 1.08E+08 - - - 1.2798 0.9997 221125_WJC_METTL3_EV_vs_WT_F02.15405.15405.2 1.70E-05 18-Dec K.NLQEAEEWYK[136.11].S "sp|P08670|VIME_HUMAN,sp|P41219|PERI_HUMAN,tr|H7C5W5|H7C5W5_HUMAN,tr|F8W835|F8W835_HUMAN,tr|B0YJC5|B0YJC5_HUMAN,tr|B0YJC4|B0YJC4_HUMAN" 6 1316.6128 2.26 15244 15405 2 1316.609753 659.3137 Vimentin OS=Homo sapiens OX=9606 GN=VIM PE=1 SV=4 4.25 2980.6 - 1.48E+06 - - - -2.3386 - 2.046 0.552 - 445.8 1 2 0 -0.0031 10 0 0 0 2.74E+08 1.21E+08 - - - 5.1154 0.9987 221125_WJC_METTL3_EV_vs_WT_F02.15412.15412.2 0.0749 14-Sep R.QLLYDAIK[136.11].H sp|Q9NYU2|UGGG1_HUMAN 1 970.5579 0.08 15249 15412 2 970.558564 486.2862 UDP-glucose:glycoprotein glucosyltransferase 1 OS=Homo sapiens OX=9606 GN=UGGT1 PE=1 SV=3 5.83 2981.5 - 2.56E+06 - - - 0.7017 - 1.636 0.233 - 246.4 1 2 0 0.0007 8 0 0 0 4.77E+06 5.99E+07 - - - 2.2463 0.9998 221125_WJC_METTL3_EV_vs_WT_F02.15416.15416.2 1.19E-05 20-Nov K.TLADAEGDVFR.G sp|Q02252|MMSA_HUMAN 1 1192.5724 2.65 15253 15416 2 1192.571454 597.2935 "Methylmalonate-semialdehyde dehydrogenase [acylating], mitochondrial OS=Homo sapiens OX=9606 GN=ALDH6A1 PE=1 SV=2" 4.03 2981.9 - 1.11E+06 - - - -0.8075 - 1.883 0.497 - 310.9 1 2 0 -0.001 11 0 0 0 2.85E+07 1.08E+07 - - - 4.4236 0.7922 221125_WJC_METTL3_EV_vs_WT_F02.15418.15418.2 0.07 14-Jul K.QLPLVK[136.11]PY.L "sp|Q00610|CLH1_HUMAN,tr|J3KS13|J3KS13_HUMAN,tr|A0A087WVQ6|A0A087WVQ6_HUMAN" 3 964.5837 0.45 15255 15418 2 964.584054 483.2991 Clathrin heavy chain 1 OS=Homo sapiens OX=9606 GN=CLTC PE=1 SV=5 8.59 2982.1 - 609349 - - - 0.3629 - 1.081 0.266 - 122.7 1 1 0 0.0003 8 0 0 0 4.67E+06 1.05E+07 - - - 1.2405 0.9998 221125_WJC_METTL3_EV_vs_WT_F02.15420.15420.2 0.114 13/20 R.LLADPTGAFGK.E sp|P30044|PRDX5_HUMAN 1 1088.5866 1.22 15256 15420 2 1088.585651 545.3006 "Peroxiredoxin-5, mitochondrial OS=Homo sapiens OX=9606 GN=PRDX5 PE=1 SV=4" 5.84 2982.3 - 1.75E+07 - - - -0.881 - 2.347 0.357 - 454 1 2 0 -0.001 11 0 0 0 1.28E+09 1.05E+09 - - - 3.9854 0.9998 221125_WJC_METTL3_EV_vs_WT_F02.15422.15422.2 3.86E-05 18-Sep K.NLQEAEEWYK.S "sp|P08670|VIME_HUMAN,sp|P41219|PERI_HUMAN,tr|H7C5W5|H7C5W5_HUMAN,tr|F8W835|F8W835_HUMAN,tr|B0YJC5|B0YJC5_HUMAN,tr|B0YJC4|B0YJC4_HUMAN" 6 1308.5986 2.27 15257 15422 2 1308.597484 655.3066 Vimentin OS=Homo sapiens OX=9606 GN=VIM PE=1 SV=4 4.25 2982.5 - 1.02E+07 - - - -0.8773 - 1.742 0.457 - 232.9 1 2 0 -0.0011 10 0 0 0 2.75E+08 1.21E+08 - - - 3.9653 0.9794 221125_WJC_METTL3_EV_vs_WT_F02.15423.15423.2 1.74 12-Aug K.EGLELLK.T "sp|P06733|ENOA_HUMAN,tr|A0A2R8Y6G6|A0A2R8Y6G6_HUMAN" 2 800.4644 1.49 15258 15423 2 800.463541 401.2395 Alpha-enolase OS=Homo sapiens OX=9606 GN=ENO1 PE=1 SV=2 4.53 2982.6 - 2.66E+06 - - - -1.0356 - 1.369 0.031 - 221.9 1 2 0 -0.0008 7 0 0 0 3.51E+08 2.36E+08 - - - 0.2649 0.994 221125_WJC_METTL3_EV_vs_WT_F02.15424.15424.2 0.287 16-Jul R.GMFTAEDLR.- sp|Q16864|VATF_HUMAN 1 1038.4804 1.64 15259 15424 2 1038.479892 520.2475 V-type proton ATPase subunit F OS=Homo sapiens OX=9606 GN=ATP6V1F PE=1 SV=2 4.37 2982.7 - 2.57E+07 - - - -0.519 - 1.145 0.211 - 87 1 2 0 -0.0005 9 0 0 0 3.09E+07 1.88E+07 - - - 0.991 0.983 221125_WJC_METTL3_EV_vs_WT_F02.15425.15425.2 0.00103 22-Sep K.GILGYTEHQVVS.S "sp|P04406|G3P_HUMAN,tr|E7EUT5|E7EUT5_HUMAN" 2 1301.6616 - 15260 15425 2 1301.660601 651.8381 Glyceraldehyde-3-phosphate dehydrogenase OS=Homo sapiens OX=9606 GN=GAPDH PE=1 SV=3 5.24 2982.7 - 1.83E+06 - - - -0.7414 - 1.681 0.449 - 174.2 1 1 0 -0.001 12 0 0 0 - - - - - 3.7236 0.9994 221125_WJC_METTL3_EV_vs_WT_F02.15427.15427.2 0.000171 20-Sep R.ELPDGPSPLLK[136.11].N sp|O14613|BORG1_HUMAN 1 1172.6532 1.64 15262 15427 2 1172.651241 587.3339 Cdc42 effector protein 2 OS=Homo sapiens OX=9606 GN=CDC42EP2 PE=1 SV=1 4.37 2982.9 - 1.74E+06 - - - -1.7047 - 1.623 0.415 - 278.2 1 2 0 -0.002 11 0 0 0 3.15E+07 1.93E+07 - - - 3.4156 0.9968 221125_WJC_METTL3_EV_vs_WT_F02.15428.15428.2 0.175 12-Jun R.LC[160.03]FEGLR[166.11].S "sp|Q15149|PLEC_HUMAN,tr|H0YDN1|H0YDN1_HUMAN" 2 903.4512 1.11 15263 15428 2 903.450622 452.7329 Plectin OS=Homo sapiens OX=9606 GN=PLEC PE=1 SV=3 5.99 2983 - 1.19E+06 - - - -0.632 - 1.451 0.17 - 119.3 1 2 0 -0.0006 7 0 0 0 6.28E+07 5.66E+07 - - - 1.4759 0.9862 221125_WJC_METTL3_EV_vs_WT_F02.15429.15429.2 2.07 12-Aug R.DLINLAK[136.11].K "sp|P22087|FBRL_HUMAN,tr|M0R299|M0R299_HUMAN,tr|M0R0P1|M0R0P1_HUMAN,tr|M0QXL5|M0QXL5_HUMAN,tr|M0R2Q4|M0R2Q4_HUMAN" 5 793.4789 0.88 15264 15429 2 793.47846 397.7467 rRNA 2'-O-methyltransferase fibrillarin OS=Homo sapiens OX=9606 GN=FBL PE=1 SV=2 5.84 2983.1 - 1.15E+06 - - - -0.5596 - 1.445 0.03 - 239.6 1 2 0 -0.0004 7 0 0 0 2.97E+08 3.38E+08 - - - 0.4288 0.9999 221125_WJC_METTL3_EV_vs_WT_F02.15433.15433.2 3.35E-05 13/24 M.MLGTEGGEGFVVK[136.11].V "sp|P31943|HNRH1_HUMAN,tr|E7EQJ0|E7EQJ0_HUMAN,tr|D6R9D3|D6R9D3_HUMAN,tr|D6RIH9|D6RIH9_HUMAN,tr|D6RJ04|D6RJ04_HUMAN,tr|E5RGV0|E5RGV0_HUMAN,tr|D6RFM3|D6RFM3_HUMAN,tr|E9PCY7|E9PCY7_HUMAN,tr|D6RIT2|D6RIT2_HUMAN,tr|E5RJ94|E5RJ94_HUMAN,tr|D6R9T0|D6R9T0_HUMAN,tr|D6RIU0|D6RIU0_HUMAN,tr|D6RAM1|D6RAM1_HUMAN,tr|D6RBM0|D6RBM0_HUMAN,tr|G8JLB6|G8JLB6_HUMAN,tr|D6RF17|D6RF17_HUMAN,tr|D6RDL0|D6RDL0_HUMAN,tr|D6RDU3|D6RDU3_HUMAN,tr|E7EN40|E7EN40_HUMAN" 19 1330.6682 0.78 15267 15433 2 1330.667194 666.3414 Heterogeneous nuclear ribonucleoprotein H OS=Homo sapiens OX=9606 GN=HNRNPH1 PE=1 SV=4 4.53 2983.6 - 1.29E+06 - - - -0.7846 - 2.424 0.544 - 359 1 2 0 -0.001 13 0 0 0 1.00E+08 1.28E+08 - - - 5.3311 0.9967 221125_WJC_METTL3_EV_vs_WT_F02.15435.15435.2 0.272 16-Aug K.DLAGSIIGK[136.11].G "sp|P61978|HNRPK_HUMAN,tr|S4R359|S4R359_HUMAN" 2 880.5109 1.23 15268 15435 2 880.510565 441.2627 Heterogeneous nuclear ribonucleoprotein K OS=Homo sapiens OX=9606 GN=HNRNPK PE=1 SV=1 5.84 2983.8 - 2.09E+06 - - - -0.4179 - 1.38 0.196 - 160.3 1 2 0 -0.0004 9 0 0 0 1.38E+09 1.12E+09 - - - 1.4203 0.9963 221125_WJC_METTL3_EV_vs_WT_F02.15436.15436.2 0.026 20-Jul R.ELPDGPSPLLK.N sp|O14613|BORG1_HUMAN 1 1164.639 1.64 15269 15436 2 1164.636989 583.3268 Cdc42 effector protein 2 OS=Homo sapiens OX=9606 GN=CDC42EP2 PE=1 SV=1 4.37 2983.9 - 2.36E+06 - - - -1.7611 - 1.442 0.237 - 145.4 1 2 0 -0.0021 11 0 0 0 2.46E+07 1.50E+07 - - - 1.781 0.9998 221125_WJC_METTL3_EV_vs_WT_F02.15437.15437.2 6.84E-05 20-Dec K.YFVEAGAMAVR[166.11].R "sp|P17987|TCPA_HUMAN,tr|F5GZ03|F5GZ03_HUMAN,tr|F5H282|F5H282_HUMAN,tr|E7EQR6|E7EQR6_HUMAN,tr|E7ERF2|E7ERF2_HUMAN" 5 1222.6044 0.31 15270 15437 2 1222.60314 612.3095 T-complex protein 1 subunit alpha OS=Homo sapiens OX=9606 GN=TCP1 PE=1 SV=1 6 2983.9 - 1.77E+06 - - - -1.0298 - 1.978 0.519 - 496 1 2 0 -0.0013 11 0 0 0 3.58E+07 1.14E+08 - - - 4.7191 0.9999 221125_WJC_METTL3_EV_vs_WT_F02.15441.15441.2 7.85E-07 20-Nov R.FVMEVEVDGQK[136.11].F "sp|Q12906|ILF3_HUMAN,sp|Q96SI9|STRBP_HUMAN" 2 1287.626 0.89 15274 15441 2 1287.627005 644.8203 Interleukin enhancer-binding factor 3 OS=Homo sapiens OX=9606 GN=ILF3 PE=1 SV=3 4.14 2984.3 - 651188 - - - 0.7502 - 2.118 0.612 - 383.9 1 2 0 0.001 11 0 0 0 1.23E+07 1.38E+07 - - - 5.5911 0.9999 221125_WJC_METTL3_EV_vs_WT_F02.15442.15442.2 1.26E-05 22-Nov K.FLAENSASVYIK.K sp|Q13618|CUL3_HUMAN 1 1340.6976 2.05 15275 15442 2 1340.69787 671.3561 Cullin-3 OS=Homo sapiens OX=9606 GN=CUL3 PE=1 SV=2 6 2984.4 - 536544 - - - 0.1887 - 2.123 0.546 - 296.1 1 2 0 0.0003 12 0 0 0 1.38E+07 6.74E+06 - - - 5.0545 0.9946 221125_WJC_METTL3_EV_vs_WT_F02.15443.15443.2 0.15 18-Aug R.FPGQLNADLR.K "sp|P04350|TBB4A_HUMAN,sp|Q9BVA1|TBB2B_HUMAN,sp|A6NNZ2|TBB8B_HUMAN,sp|P07437|TBB5_HUMAN,sp|Q13509|TBB3_HUMAN,sp|Q13885|TBB2A_HUMAN,sp|P68371|TBB4B_HUMAN,sp|Q9BUF5|TBB6_HUMAN,sp|Q3ZCM7|TBB8_HUMAN,sp|Q9H4B7|TBB1_HUMAN,tr|M0R2D3|M0R2D3_HUMAN,tr|A0A0B4J269|A0A0B4J269_HUMAN,tr|Q5ST81|Q5ST81_HUMAN,tr|Q5JP53|Q5JP53_HUMAN,tr|K7ESM5|K7ESM5_HUMAN,tr|A0A075B736|A0A075B736_HUMAN,tr|G3V2A3|G3V2A3_HUMAN,tr|Q5SQY0|Q5SQY0_HUMAN" 18 1129.588 1.02 15276 15443 2 1129.584692 565.8013 Tubulin beta-4A chain OS=Homo sapiens OX=9606 GN=TUBB4A PE=1 SV=2 5.84 2984.5 - 502225 - - - -2.9347 - 1.363 0.306 - 153.9 1 2 0 -0.0033 10 0 0 0 4.92E+07 4.81E+07 - - - 2.1645 0.9998 221125_WJC_METTL3_EV_vs_WT_F02.15445.15445.2 0.000794 22-Aug R.FTEYSMTSSVMR.R "sp|Q96GA3|LTV1_HUMAN,tr|A0A075B6Q4|A0A075B6Q4_HUMAN" 2 1437.6268 1.09 15278 15445 2 1437.626844 719.8207 Protein LTV1 homolog OS=Homo sapiens OX=9606 GN=LTV1 PE=1 SV=1 6 2984.8 - 134510 - - - 0.0049 - 1.664 0.518 - 158.5 1 2 0 0 12 0 0 0 3.95E+06 3.63E+06 - - - 4.2068 0.9993 221125_WJC_METTL3_EV_vs_WT_F02.15449.15449.2 0.00739 20-Sep R.IYVGNLPTDVR.E "sp|Q13242|SRSF9_HUMAN,tr|H0YIB4|H0YIB4_HUMAN,tr|S4R3G0|S4R3G0_HUMAN" 3 1245.6717 2.05 15280 15449 2 1245.67402 623.8431 Serine\arginine-rich splicing factor 9 OS=Homo sapiens OX=9606 GN=SRSF9 PE=1 SV=1 5.84 2985.2 - 3.07E+06 - - - 1.8327 - 1.778 0.387 - 330.7 1 2 0 0.0023 11 0 0 0 2.28E+08 1.12E+08 - - - 3.4555 0.9916 221125_WJC_METTL3_EV_vs_WT_F02.15450.15450.2 0.00138 16-Oct K.LYQTPLELK[136.11].L "sp|P52948|NUP98_HUMAN,tr|A0A3B3ITD8|A0A3B3ITD8_HUMAN,tr|H7C3P6|H7C3P6_HUMAN" 3 1111.6369 2.11 15281 15450 2 1111.639455 556.8257 Nuclear pore complex protein Nup98-Nup96 OS=Homo sapiens OX=9606 GN=NUP98 PE=1 SV=4 6 2985.3 - 2.10E+06 - - - 2.3335 - 1.566 0.157 - 253.2 1 2 0 0.0026 9 0 0 0 8.62E+07 4.09E+07 - - - 1.4974 0.9999 221125_WJC_METTL3_EV_vs_WT_F02.15451.15451.2 0.000344 22-Sep K.LFGAPEPSTIAR[166.11].S "sp|Q6PKG0|LARP1_HUMAN,tr|A0A0B4J210|A0A0B4J210_HUMAN,tr|H0YC33|H0YC33_HUMAN,tr|E5RH50|E5RH50_HUMAN" 4 1267.68 1.66 15282 15451 2 1267.680228 634.8473 La-related protein 1 OS=Homo sapiens OX=9606 GN=LARP1 PE=1 SV=2 6 2985.4 - 1.87E+06 - - - 0.1743 - 1.985 0.5 - 236.9 1 2 0 0.0002 12 0 0 0 1.61E+08 9.72E+07 - - - 4.5379 0.9931 221125_WJC_METTL3_EV_vs_WT_F02.15452.15452.2 0.0131 12-Jul R.LC[160.03]FEGLR.S "sp|Q15149|PLEC_HUMAN,tr|H0YDN1|H0YDN1_HUMAN" 2 893.4429 1.04 15283 15452 2 893.442793 447.7287 Plectin OS=Homo sapiens OX=9606 GN=PLEC PE=1 SV=3 5.99 2985.4 - 1.71E+06 - - - -0.1455 - 1.429 0.095 - 162.6 1 2 0 -0.0001 7 0 0 0 6.37E+07 6.12E+07 - - - 0.8737 0.9992 221125_WJC_METTL3_EV_vs_WT_F02.15454.15454.2 0.00112 20-Sep R.FVMEVEVDGQK.F "sp|Q12906|ILF3_HUMAN,sp|Q96SI9|STRBP_HUMAN" 2 1279.6118 0.89 15285 15454 2 1279.613887 640.8132 Interleukin enhancer-binding factor 3 OS=Homo sapiens OX=9606 GN=ILF3 PE=1 SV=3 4.14 2985.6 - 1.26E+06 - - - 1.6005 - 1.609 0.386 - 210.5 1 2 0 0.002 11 0 0 0 1.23E+07 1.38E+07 - - - 3.178 0.9997 221125_WJC_METTL3_EV_vs_WT_F02.15455.15455.2 0.000646 16-Oct R.C[160.03]PVEIPPIR.R sp|Q5T749|KPRP_HUMAN 1 1079.5798 0.06 15286 15455 2 1079.577742 540.7972 Keratinocyte proline-rich protein OS=Homo sapiens OX=9606 GN=KPRP PE=1 SV=1 5.99 2985.7 - 1.02E+06 - - - -1.8609 - 1.867 0.466 - 482.4 1 2 0 -0.002 9 0 0 0 3.77E+07 5.98E+08 - - - 4.2885 0.9996 221125_WJC_METTL3_EV_vs_WT_F02.15456.15456.2 0.0018 14-Sep R.SDTFINLR.E sp|P17655|CAN2_HUMAN 1 964.4978 2.3 15287 15456 2 964.496846 483.2562 Calpain-2 catalytic subunit OS=Homo sapiens OX=9606 GN=CAPN2 PE=1 SV=6 5.55 2985.8 - 957359 - - - -0.9839 - 1.735 0.368 - 343.4 1 2 0 -0.0009 8 0 0 0 2.07E+07 9.00E+06 - - - 3.4206 0.9997 221125_WJC_METTL3_EV_vs_WT_F02.15457.15457.2 0.000396 20-Oct K.YFVEAGAMAVR.R "sp|P17987|TCPA_HUMAN,tr|F5GZ03|F5GZ03_HUMAN,tr|F5H282|F5H282_HUMAN,tr|E7EQR6|E7EQR6_HUMAN,tr|E7ERF2|E7ERF2_HUMAN" 5 1212.5961 0.31 15288 15457 2 1212.595154 607.3053 T-complex protein 1 subunit alpha OS=Homo sapiens OX=9606 GN=TCP1 PE=1 SV=1 6 2985.8 - 914457 - - - -0.8041 - 1.695 0.446 - 160 1 2 0 -0.001 11 0 0 0 3.58E+07 1.14E+08 - - - 3.7624 0.8969 221125_WJC_METTL3_EV_vs_WT_F02.15458.15458.3 2.44 Jul-40 K.TVQPHTVTALR[166.11].N sp|Q6PJW8|CNST_HUMAN 1 1231.6912 0.93 15289 15458 3 1231.691754 411.571 Consortin OS=Homo sapiens OX=9606 GN=CNST PE=1 SV=3 9.44 2986 - 885021 - - - 0.4173 - 1.409 0.082 - 39.5 1 2 0 0.0005 11 0 0 0 2.15E+07 2.31E+07 - - - 0.4281 0.9937 221125_WJC_METTL3_EV_vs_WT_F02.15459.15459.2 0.176 14-May R.AFVTDWDK.V sp|Q9NVI7|ATD3A_HUMAN 1 980.4603 2.6 15290 15459 2 980.460319 491.2374 ATPase family AAA domain-containing protein 3A OS=Homo sapiens OX=9606 GN=ATAD3A PE=1 SV=2 4.21 2986.1 - 794122 - - - -0.0286 - 1.194 0.203 - 73.6 2 2 0 0 8 0 0 0 1.15E+08 4.43E+07 - - - 0.9406 0.9967 221125_WJC_METTL3_EV_vs_WT_F02.15461.15461.3 0.0222 Dec-40 K.LVQEALEAVPR.G "sp|Q15269|PWP2_HUMAN,tr|A0A0B4J2E5|A0A0B4J2E5_HUMAN" 2 1223.6874 0.52 15292 15461 3 1223.684472 408.9031 Periodic tryptophan protein 2 homolog OS=Homo sapiens OX=9606 GN=PWP2 PE=2 SV=2 4.53 2986.3 - 614866 - - - -2.3821 - 2.307 0.194 - 146.4 1 2 0 -0.0029 11 0 0 0 9.70E+06 1.88E+07 - - - 3.0769 1 221125_WJC_METTL3_EV_vs_WT_F02.15463.15463.2 5.35E-08 22-Nov R.FTEYSMTSSVMR[166.11].R "sp|Q96GA3|LTV1_HUMAN,tr|A0A075B6Q4|A0A075B6Q4_HUMAN" 2 1447.6351 1.09 15294 15463 2 1447.630733 724.8248 Protein LTV1 homolog OS=Homo sapiens OX=9606 GN=LTV1 PE=1 SV=1 6 2986.6 - 383331 - - - -3.0215 - 2.258 0.682 - 423.1 1 2 0 -0.0044 12 0 0 0 3.95E+06 3.63E+06 - - - 6.2199 0.9998 221125_WJC_METTL3_EV_vs_WT_F02.15464.15464.2 0.000125 22-Aug R.FTEYSMTSSVMR.R "sp|Q96GA3|LTV1_HUMAN,tr|A0A075B6Q4|A0A075B6Q4_HUMAN" 2 1437.6268 1.09 15295 15464 2 1437.62412 719.8207 Protein LTV1 homolog OS=Homo sapiens OX=9606 GN=LTV1 PE=1 SV=1 6 2986.7 - 369588 - - - -1.8899 - 1.936 0.565 - 210.9 1 2 0 -0.0027 12 0 0 0 3.95E+06 3.63E+06 - - - 4.9515 0.9999 221125_WJC_METTL3_EV_vs_WT_F02.15468.15468.2 3.61E-05 20-Oct R.IYVGNLPTDVR[166.11].E "sp|Q13242|SRSF9_HUMAN,tr|H0YIB4|H0YIB4_HUMAN,tr|S4R3G0|S4R3G0_HUMAN" 3 1255.68 2.05 15297 15468 2 1255.680625 628.8473 Serine\arginine-rich splicing factor 9 OS=Homo sapiens OX=9606 GN=SRSF9 PE=1 SV=1 5.84 2987.2 - 6.87E+06 - - - 0.4922 - 2.06 0.548 - 368.1 1 2 0 0.0006 11 0 0 0 2.28E+08 1.12E+08 - - - 5.0434 0.9999 221125_WJC_METTL3_EV_vs_WT_F02.15470.15470.2 0.00392 14/22 K.LAAQSC[160.03]ALSLVR[166.11].Q sp|Q08211|DHX9_HUMAN 1 1297.7052 0.89 15299 15470 2 1297.705039 649.8599 ATP-dependent RNA helicase A OS=Homo sapiens OX=9606 GN=DHX9 PE=1 SV=4 8.25 2987.3 - 2.92E+06 - - - -0.1056 - 2.806 0.439 - 871.3 1 2 0 -0.0001 12 0 0 0 1.28E+08 1.44E+08 - - - 4.9981 0.9997 221125_WJC_METTL3_EV_vs_WT_F02.15473.15473.2 0.00228 22-Dec K.LAAQSC[160.03]ALSLVR.Q sp|Q08211|DHX9_HUMAN 1 1287.6969 0.89 15302 15473 2 1287.695307 644.8557 ATP-dependent RNA helicase A OS=Homo sapiens OX=9606 GN=DHX9 PE=1 SV=4 8.25 2987.5 - 2.34E+06 - - - -1.2418 - 2.243 0.358 - 376.4 1 2 0 -0.0016 12 0 0 0 1.28E+08 1.44E+08 - - - 3.8102 1 221125_WJC_METTL3_EV_vs_WT_F02.15475.15475.2 2.63E-09 13/24 R.LAPDYDALDVANK[136.11].L "sp|P62750|RL23A_HUMAN,tr|K7EMA7|K7EMA7_HUMAN,tr|H7BY10|H7BY10_HUMAN,tr|K7ERT8|K7ERT8_HUMAN,tr|A8MUS3|A8MUS3_HUMAN,tr|K7EJV9|K7EJV9_HUMAN" 6 1411.7075 1.15 15304 15475 2 1411.707479 706.861 60S ribosomal protein L23a OS=Homo sapiens OX=9606 GN=RPL23A PE=1 SV=1 3.93 2987.6 - 1.98E+06 - - - 0.0135 - 2.551 0.605 - 556 1 2 0 0 13 0 0 0 7.08E+07 6.18E+07 - - - 5.913 0.9999 221125_WJC_METTL3_EV_vs_WT_F02.15478.15478.2 9.66E-07 13/24 R.LAPDYDALDVANK.L "sp|P62750|RL23A_HUMAN,tr|K7EMA7|K7EMA7_HUMAN,tr|H7BY10|H7BY10_HUMAN,tr|K7ERT8|K7ERT8_HUMAN,tr|A8MUS3|A8MUS3_HUMAN,tr|K7EJV9|K7EJV9_HUMAN" 6 1403.6933 0.78 15307 15478 2 1403.691957 702.8539 60S ribosomal protein L23a OS=Homo sapiens OX=9606 GN=RPL23A PE=1 SV=1 3.93 2987.9 - 1.44E+06 - - - -0.9283 - 2.383 0.565 - 598.5 1 2 0 -0.0013 13 0 0 0 4.78E+07 6.14E+07 - - - 5.4424 0.9986 221125_WJC_METTL3_EV_vs_WT_F02.15481.15481.2 0.029 18-Sep R.LQQVDPVLLK.D "sp|O75179|ANR17_HUMAN,tr|H0YM23|H0YM23_HUMAN,tr|A0A1W2PQ15|A0A1W2PQ15_HUMAN,tr|H0YLQ3|H0YLQ3_HUMAN" 4 1151.6914 5 15310 15481 2 1151.691134 576.853 Ankyrin repeat domain-containing protein 17 OS=Homo sapiens OX=9606 GN=ANKRD17 PE=1 SV=3 5.84 2988.3 - 632212 - - - -0.2396 - 1.736 0.202 - 205.8 1 2 0 -0.0003 10 0 0 0 1.44E+07 2.89E+06 - - - 2.0725 1 221125_WJC_METTL3_EV_vs_WT_F02.15483.15483.2 2.40E-08 14/26 K.IFVGGLSPDTPEEK[136.11].L "sp|Q14103|HNRPD_HUMAN,tr|H0Y8G5|H0Y8G5_HUMAN,tr|D6RF44|D6RF44_HUMAN,tr|D6RAF8|D6RAF8_HUMAN,tr|H0YA96|H0YA96_HUMAN" 5 1495.765 1.47 15312 15483 2 1495.764389 748.8898 Heterogeneous nuclear ribonucleoprotein D0 OS=Homo sapiens OX=9606 GN=HNRNPD PE=1 SV=1 4.14 2988.5 - 426529 - - - -0.3918 - 2.705 0.627 - 545.3 1 2 0 -0.0006 14 0 0 0 7.64E+08 5.20E+08 - - - 6.169 0.9997 221125_WJC_METTL3_EV_vs_WT_F02.15486.15486.2 0.00545 20-Aug R.TFIVGAQMNVK.E "sp|P46379|BAG6_HUMAN,tr|F6UR09|F6UR09_HUMAN,tr|A0A7I2V508|A0A7I2V508_HUMAN,tr|F6U1F2|F6U1F2_HUMAN,tr|F6U341|F6U341_HUMAN,tr|F6WML8|F6WML8_HUMAN,tr|A0A0G2JJM1|A0A0G2JJM1_HUMAN,tr|X6REW1|X6REW1_HUMAN,tr|A0A7I2V3H1|A0A7I2V3H1_HUMAN,tr|A0A7P0MQS5|A0A7P0MQS5_HUMAN,tr|F6XTU0|F6XTU0_HUMAN,tr|F6X9W3|F6X9W3_HUMAN,tr|F6VEM6|F6VEM6_HUMAN,tr|A0A0G2JJR8|A0A0G2JJR8_HUMAN,tr|F6S6P2|F6S6P2_HUMAN,tr|F6TC96|F6TC96_HUMAN,tr|A0A0G2JL47|A0A0G2JL47_HUMAN,tr|A0A024RCR6|A0A024RCR6_HUMAN,tr|A0A0G2JK23|A0A0G2JK23_HUMAN,tr|A0A1B0GX79|A0A1B0GX79_HUMAN" 20 1206.6431 1.28 15313 15486 2 1206.64394 604.3288 Large proline-rich protein BAG6 OS=Homo sapiens OX=9606 GN=BAG6 PE=1 SV=2 8.41 2988.9 - 2.87E+06 - - - 0.7135 - 1.909 0.395 - 153.5 1 2 0 0.0009 11 0 0 0 5.18E+07 4.06E+07 - - - 3.7074 1 221125_WJC_METTL3_EV_vs_WT_F02.15487.15487.2 2.53E-06 14/20 R.APQVLVLAPTR[166.11].E sp|Q9NR30|DDX21_HUMAN 1 1173.7109 0.97 15314 15487 2 1173.709749 587.8627 Nucleolar RNA helicase 2 OS=Homo sapiens OX=9606 GN=DDX21 PE=1 SV=5 9.79 2989 - 2.36E+06 - - - -0.9917 - 2.565 0.563 - 1063.2 1 2 0 -0.0012 11 0 0 0 1.31E+08 1.36E+08 - - - 5.7472 0.9989 221125_WJC_METTL3_EV_vs_WT_F02.15488.15488.2 0.00125 18-Oct K.VVNLGVLAQK.S "sp|Q8NI36|WDR36_HUMAN,tr|A0A0A0MTB8|A0A0A0MTB8_HUMAN" 2 1039.639 0.93 15315 15488 2 1039.639755 520.8268 WD repeat-containing protein 36 OS=Homo sapiens OX=9606 GN=WDR36 PE=1 SV=1 8.72 2989 - 3.39E+06 - - - 0.7455 - 1.971 0.205 - 282 1 2 0 0.0008 10 0 0 0 4.17E+07 4.48E+07 - - - 2.4489 0.9956 221125_WJC_METTL3_EV_vs_WT_F02.15489.15489.2 0.000867 16-Aug R.YLLGDMEGR[166.11].L "sp|Q16531|DDB1_HUMAN,tr|F5GWI0|F5GWI0_HUMAN,tr|A0A7P0TAK7|A0A7P0TAK7_HUMAN,tr|A0A7P0T870|A0A7P0T870_HUMAN,tr|A0A7P0TB30|A0A7P0TB30_HUMAN,tr|A0A7P0Z3Z5|A0A7P0Z3Z5_HUMAN,tr|F5GY55|F5GY55_HUMAN,tr|A0A7P0Z4B9|A0A7P0Z4B9_HUMAN,tr|A0A7P0T965|A0A7P0T965_HUMAN" 9 1062.5044 0.88 15316 15489 2 1062.499315 532.2595 DNA damage-binding protein 1 OS=Homo sapiens OX=9606 GN=DDB1 PE=1 SV=1 4.37 2989.1 - 1.83E+06 - - - -4.7397 - 1.717 0.416 - 193.5 1 2 0 -0.005 9 0 0 0 1.88E+07 2.13E+07 - - - 3.6759 1 221125_WJC_METTL3_EV_vs_WT_F02.15493.15493.2 1.38E-08 16/26 K.IFVGGLSPDTPEEK.L "sp|Q14103|HNRPD_HUMAN,tr|H0Y8G5|H0Y8G5_HUMAN,tr|D6RF44|D6RF44_HUMAN,tr|D6RAF8|D6RAF8_HUMAN,tr|H0YA96|H0YA96_HUMAN" 5 1487.7508 1.47 15320 15493 2 1487.749909 744.8827 Heterogeneous nuclear ribonucleoprotein D0 OS=Homo sapiens OX=9606 GN=HNRNPD PE=1 SV=1 4.14 2989.5 - 1.19E+06 - - - -0.5821 - 2.652 0.629 - 736.8 1 2 0 -0.0009 14 0 0 0 7.64E+08 5.20E+08 - - - 6.134 0.9847 221125_WJC_METTL3_EV_vs_WT_F02.15494.15494.2 9.97E-05 24-Dec H.SLTPVAQADPLVR.R "sp|Q14444|CAPR1_HUMAN,tr|G3V153|G3V153_HUMAN" 2 1365.7616 0.95 15321 15494 2 1365.76358 683.8881 Caprin-1 OS=Homo sapiens OX=9606 GN=CAPRIN1 PE=1 SV=2 5.55 2989.6 - 1.16E+06 - - - 1.4388 - 2.407 0.426 - 473.7 1 1 0 0.002 13 0 0 0 2.22E+08 2.33E+08 - - - 4.4412 0.9017 221125_WJC_METTL3_EV_vs_WT_F02.15496.15496.2 0.0118 18-Sep K.ELGITALHIK.L "sp|P62263|RS14_HUMAN,tr|A0A2R8Y811|A0A2R8Y811_HUMAN,tr|E5RH77|E5RH77_HUMAN" 3 1093.6495 1.19 15323 15496 2 1093.656881 547.832 40S ribosomal protein S14 OS=Homo sapiens OX=9606 GN=RPS14 PE=1 SV=3 6.85 2989.8 - 593935 - - - 6.7078 - 1.475 0.236 - 191.5 1 2 0 0.0073 10 0 0 0 6.57E+06 5.50E+06 - - - 1.8667 0.9982 221125_WJC_METTL3_EV_vs_WT_F02.15499.15499.2 0.152 16-Nov R.AGLQFPVGR[166.11].V "sp|P16104|H2AX_HUMAN,sp|Q9BTM1|H2AJ_HUMAN,sp|Q93077|H2A1C_HUMAN,sp|Q99878|H2A1J_HUMAN,sp|Q16777|H2A2C_HUMAN,sp|Q8IUE6|H2A2B_HUMAN,sp|Q96QV6|H2A1A_HUMAN,sp|P0C0S5|H2AZ_HUMAN,sp|P04908|H2A1B_HUMAN,sp|P20671|H2A1D_HUMAN,sp|P0C0S8|H2A1_HUMAN,sp|Q6FI13|H2A2A_HUMAN,sp|Q96KK5|H2A1H_HUMAN,sp|Q71UI9|H2AV_HUMAN,sp|Q7L7L0|H2A3_HUMAN,tr|A0A0U1RR32|A0A0U1RR32_HUMAN,tr|A0A0U1RRH7|A0A0U1RRH7_HUMAN,tr|A0A3B3IS11|A0A3B3IS11_HUMAN,tr|C9J0D1|C9J0D1_HUMAN,tr|A0A494C189|A0A494C189_HUMAN" 20 953.5322 1.16 15325 15499 2 953.531358 477.7734 Histone H2AX OS=Homo sapiens OX=9606 GN=H2AX PE=1 SV=2 9.79 2990.2 - 6.57E+06 - - - -0.904 - 1.68 0.199 - 464.7 1 2 0 -0.0009 9 0 0 0 1.35E+10 1.16E+10 - - - 2.0114 0.9999 221125_WJC_METTL3_EV_vs_WT_F02.15502.15502.2 3.34E-06 20-Dec R.APQVLVLAPTR.E sp|Q9NR30|DDX21_HUMAN 1 1163.7026 0.97 15327 15502 2 1163.702209 582.8586 Nucleolar RNA helicase 2 OS=Homo sapiens OX=9606 GN=DDX21 PE=1 SV=5 9.79 2990.5 - 3.14E+06 - - - -0.3729 - 2.344 0.469 - 582.9 1 2 0 -0.0004 11 0 0 0 1.30E+08 1.35E+08 - - - 4.8094 0.9974 221125_WJC_METTL3_EV_vs_WT_F02.15503.15503.2 1.55 20-Sep R.TFIVGAQMNVK[136.11].E "sp|P46379|BAG6_HUMAN,tr|F6UR09|F6UR09_HUMAN,tr|A0A7I2V508|A0A7I2V508_HUMAN,tr|F6U1F2|F6U1F2_HUMAN,tr|F6U341|F6U341_HUMAN,tr|F6WML8|F6WML8_HUMAN,tr|A0A0G2JJM1|A0A0G2JJM1_HUMAN,tr|X6REW1|X6REW1_HUMAN,tr|A0A7I2V3H1|A0A7I2V3H1_HUMAN,tr|A0A7P0MQS5|A0A7P0MQS5_HUMAN,tr|F6XTU0|F6XTU0_HUMAN,tr|F6X9W3|F6X9W3_HUMAN,tr|F6VEM6|F6VEM6_HUMAN,tr|A0A0G2JJR8|A0A0G2JJR8_HUMAN,tr|F6S6P2|F6S6P2_HUMAN,tr|F6TC96|F6TC96_HUMAN,tr|A0A0G2JL47|A0A0G2JL47_HUMAN,tr|A0A024RCR6|A0A024RCR6_HUMAN,tr|A0A0G2JK23|A0A0G2JK23_HUMAN,tr|A0A1B0GX79|A0A1B0GX79_HUMAN" 20 1214.6573 1.27 15328 15503 2 1214.656692 608.3359 Large proline-rich protein BAG6 OS=Homo sapiens OX=9606 GN=BAG6 PE=1 SV=2 8.41 2990.5 - 2.69E+06 - - - -0.4833 - 1.585 0.177 - 185.3 1 2 0 -0.0006 11 0 0 0 5.16E+07 4.06E+07 - - - 1.5941 0.9547 221125_WJC_METTL3_EV_vs_WT_F02.15505.15505.2 0.00831 16-Jul A.GGVMTALIK[136.11].R "sp|P0DMV8|HS71A_HUMAN,sp|P34931|HS71L_HUMAN,sp|P0DMV9|HS71B_HUMAN,tr|Q53FA3|Q53FA3_HUMAN,tr|V9GZ37|V9GZ37_HUMAN,tr|A0A0G2JIW1|A0A0G2JIW1_HUMAN" 6 896.5245 0.1 15330 15505 2 896.523907 449.2695 Heat shock 70 kDa protein 1A OS=Homo sapiens OX=9606 GN=HSPA1A PE=1 SV=1 8.75 2990.7 - 1.53E+06 - - - -0.6324 - 1.542 0.317 - 124.6 1 1 0 -0.0006 9 0 0 0 3.18E+06 3.24E+07 - - - 2.6351 0.9996 221125_WJC_METTL3_EV_vs_WT_F02.15506.15506.2 0.00157 13/24 K.IAVEPVNPSELPK.M sp|Q15029|U5S1_HUMAN 1 1391.766 2.34 15331 15506 2 1391.763691 696.8903 116 kDa U5 small nuclear ribonucleoprotein component OS=Homo sapiens OX=9606 GN=EFTUD2 PE=1 SV=1 4.53 2990.8 - 702910 - - - -1.6813 - 2.393 0.337 - 440.1 1 2 0 -0.0023 13 0 0 0 1.58E+08 6.75E+07 - - - 3.7688 0.9903 221125_WJC_METTL3_EV_vs_WT_F02.15512.15512.2 1.19 16-Jul K.DLAGSIIGK.G "sp|P61978|HNRPK_HUMAN,tr|S4R359|S4R359_HUMAN" 2 872.4967 1.23 15335 15512 2 872.496138 437.2556 Heterogeneous nuclear ribonucleoprotein K OS=Homo sapiens OX=9606 GN=HNRNPK PE=1 SV=1 5.84 2991.6 - 1.21E+08 - - - -0.682 - 1.236 0.14 - 117.5 1 2 0 -0.0006 9 0 0 0 1.38E+09 1.12E+09 - - - 0.6878 0.9993 221125_WJC_METTL3_EV_vs_WT_F02.15513.15513.2 0.0295 18-Aug K.VVNLGVLAQK[136.11].S "sp|Q8NI36|WDR36_HUMAN,tr|A0A0A0MTB8|A0A0A0MTB8_HUMAN" 2 1047.6532 0.93 15336 15513 2 1047.65345 524.8339 WD repeat-containing protein 36 OS=Homo sapiens OX=9606 GN=WDR36 PE=1 SV=1 8.72 2991.6 - 7.80E+06 - - - 0.2577 - 1.515 0.336 - 129.6 1 2 0 0.0003 10 0 0 0 4.17E+07 4.48E+07 - - - 2.6822 0.9996 221125_WJC_METTL3_EV_vs_WT_F02.15515.15515.2 0.00017 18-Sep K.EVFSIAGTVK[136.11].R "sp|Q9P2K5|MYEF2_HUMAN,tr|A0A0A0MR39|A0A0A0MR39_HUMAN,tr|A0A087WUT0|A0A087WUT0_HUMAN,tr|H0YN19|H0YN19_HUMAN,tr|A0A0A0MQW0|A0A0A0MQW0_HUMAN" 5 1057.5899 0.64 15338 15515 2 1057.591542 529.8022 Myelin expression factor 2 OS=Homo sapiens OX=9606 GN=MYEF2 PE=1 SV=3 6.1 2991.7 - 2.08E+06 - - - 1.5422 - 1.897 0.437 - 265.8 1 2 0 0.0016 10 0 0 0 6.73E+07 1.06E+08 - - - 4.0554 0.9995 221125_WJC_METTL3_EV_vs_WT_F02.15517.15517.2 0.000524 14-Aug K.VITMFVQR.Q "sp|P13010|XRCC5_HUMAN,tr|C9JZ81|C9JZ81_HUMAN,tr|H7C0H9|H7C0H9_HUMAN" 3 992.5477 0.89 15340 15517 2 992.545734 497.2811 X-ray repair cross-complementing protein 5 OS=Homo sapiens OX=9606 GN=XRCC5 PE=1 SV=3 9.72 2991.9 - 990784 - - - -2.0029 - 1.839 0.393 - 204.5 1 2 0 -0.002 8 0 0 0 2.43E+07 2.75E+07 - - - 3.7805 0.9987 221125_WJC_METTL3_EV_vs_WT_F02.15520.15520.2 0.00112 24-Oct R.ITSPLMEPSSIEK[136.11].L sp|P28066|PSA5_HUMAN 1 1438.7469 1.1 15343 15520 2 1438.75118 720.3807 Proteasome subunit alpha type-5 OS=Homo sapiens OX=9606 GN=PSMA5 PE=1 SV=3 4.53 2992.3 - 267767 - - - 2.9873 - 1.921 0.392 - 257.6 1 2 0 0.0043 13 0 0 0 9.91E+06 9.00E+06 - - - 3.6105 0.9998 221125_WJC_METTL3_EV_vs_WT_F02.15522.15522.2 0.0878 18-Nov R.VPLVAPEDLR.D "sp|O14744|ANM5_HUMAN,tr|C9JSX3|C9JSX3_HUMAN,tr|G3V580|G3V580_HUMAN,tr|G3V2X6|G3V2X6_HUMAN,tr|G3V5L5|G3V5L5_HUMAN,tr|H0YJX6|H0YJX6_HUMAN" 6 1107.6288 3.32 15344 15522 2 1107.628446 554.8217 Protein arginine N-methyltransferase 5 OS=Homo sapiens OX=9606 GN=PRMT5 PE=1 SV=4 4.37 2992.5 - 1.83E+07 - - - -0.3277 - 2.302 0.387 - 639.5 1 2 0 -0.0004 10 0 0 0 4.54E+08 1.37E+08 - - - 4.2266 0.9999 221125_WJC_METTL3_EV_vs_WT_F02.15524.15524.2 0.000115 18-Nov R.VPLVAPEDLR[166.11].D "sp|O14744|ANM5_HUMAN,tr|C9JSX3|C9JSX3_HUMAN,tr|G3V580|G3V580_HUMAN,tr|G3V2X6|G3V2X6_HUMAN,tr|G3V5L5|G3V5L5_HUMAN,tr|H0YJX6|H0YJX6_HUMAN" 6 1117.6371 3.31 15345 15524 2 1117.63708 559.8258 Protein arginine N-methyltransferase 5 OS=Homo sapiens OX=9606 GN=PRMT5 PE=1 SV=4 4.37 2992.7 - 5.69E+06 - - - 0.0009 - 2.3 0.425 - 660.4 1 2 0 0 10 0 0 0 4.53E+08 1.37E+08 - - - 4.505 0.9998 221125_WJC_METTL3_EV_vs_WT_F02.15525.15525.2 4.88E-05 18-Oct K.EVFSIAGTVK.R "sp|Q9P2K5|MYEF2_HUMAN,tr|A0A0A0MR39|A0A0A0MR39_HUMAN,tr|A0A087WUT0|A0A087WUT0_HUMAN,tr|H0YN19|H0YN19_HUMAN,tr|A0A0A0MQW0|A0A0A0MQW0_HUMAN" 5 1049.5757 0.64 15346 15525 2 1049.575137 525.7951 Myelin expression factor 2 OS=Homo sapiens OX=9606 GN=MYEF2 PE=1 SV=3 6.1 2992.8 - 3.65E+06 - - - -0.5469 - 1.899 0.474 - 301.6 1 2 0 -0.0006 10 0 0 0 6.87E+07 1.08E+08 - - - 4.3319 0.9993 221125_WJC_METTL3_EV_vs_WT_F02.15526.15526.2 0.0102 16-Jul R.GLFDEYGSK[136.11].K "sp|Q58FF3|ENPLL_HUMAN,sp|P14625|ENPL_HUMAN,tr|A0A7P0T917|A0A7P0T917_HUMAN,tr|A0A7P0T823|A0A7P0T823_HUMAN,tr|A0A7P0TAE1|A0A7P0TAE1_HUMAN,tr|H0YIV0|H0YIV0_HUMAN,tr|A0A7P0TAY2|A0A7P0TAY2_HUMAN,tr|A0A087WT78|A0A087WT78_HUMAN,tr|A0A7P0TBC2|A0A7P0TBC2_HUMAN,tr|A0A7P0TAT8|A0A7P0TAT8_HUMAN" 10 1022.48 0.83 15347 15526 2 1022.480767 512.2473 Putative endoplasmin-like protein OS=Homo sapiens OX=9606 GN=HSP90B2P PE=5 SV=1 4.37 2992.9 - 1.11E+06 - - - 0.7247 - 1.429 0.371 - 111.8 1 2 0 0.0007 9 0 0 0 3.27E+07 3.95E+07 - - - 2.8137 0.9994 221125_WJC_METTL3_EV_vs_WT_F02.15527.15527.2 2.26E-05 14/22 R.VEEDVASDLVMK[136.11].V sp|Q9NYU2|UGGG1_HUMAN 1 1341.6577 0.48 15348 15527 2 1341.652983 671.8361 UDP-glucose:glycoprotein glucosyltransferase 1 OS=Homo sapiens OX=9606 GN=UGGT1 PE=1 SV=3 3.92 2993 - 820128 - - - -3.5404 - 2.56 0.516 - 636.2 1 2 0 -0.0047 12 0 0 0 9.60E+06 1.99E+07 - - - 5.324 0.9962 221125_WJC_METTL3_EV_vs_WT_F02.15528.15528.2 0.447 18-Sep K.AISSDMYFGR[166.11].Q "sp|Q9NP61|ARFG3_HUMAN,tr|H0Y6A0|H0Y6A0_HUMAN" 2 1155.5258 1.09 15349 15528 2 1155.525931 578.7702 ADP-ribosylation factor GTPase-activating protein 3 OS=Homo sapiens OX=9606 GN=ARFGAP3 PE=1 SV=1 5.88 2993.1 - 788077 - - - 0.1013 - 1.259 0.219 - 200.6 1 2 0 0.0001 10 0 0 0 9.56E+06 8.79E+06 - - - 1.3014 0.9998 221125_WJC_METTL3_EV_vs_WT_F02.15529.15529.2 0.000294 16-Oct R.LFDDVPQVR[166.11].R "sp|Q86Y56|DAAF5_HUMAN,tr|H0Y650|H0Y650_HUMAN" 2 1097.5745 0.51 15350 15529 2 1097.573985 549.7945 Dynein axonemal assembly factor 5 OS=Homo sapiens OX=9606 GN=DNAAF5 PE=1 SV=4 4.21 2993.2 - 635272 - - - -0.4501 - 1.86 0.467 - 338.4 1 2 0 -0.0005 9 0 0 0 2.71E+06 5.36E+06 - - - 4.2855 0.9881 221125_WJC_METTL3_EV_vs_WT_F02.15530.15530.2 0.0987 12-Aug K.IVQWDIR[166.11].S "sp|O60508|PRP17_HUMAN,tr|Q5SRN1|Q5SRN1_HUMAN" 2 938.5213 1.02 15351 15530 2 938.523883 470.2679 Pre-mRNA-processing factor 17 OS=Homo sapiens OX=9606 GN=CDC40 PE=1 SV=1 5.84 2993.4 - 764430 - - - 2.7298 - 1.479 0.157 - 209.2 1 2 0 0.0026 7 0 0 0 1.63E+07 1.60E+07 - - - 1.4399 0.9997 221125_WJC_METTL3_EV_vs_WT_F02.15532.15532.3 0.0236 Dec-36 R.FPLSHLDALK.Q sp|Q8IUF8|RIOX2_HUMAN 1 1139.6339 1.09 15353 15532 3 1139.63355 380.8852 Ribosomal oxygenase 2 OS=Homo sapiens OX=9606 GN=RIOX2 PE=1 SV=1 6.74 2993.6 - 347565 - - - -0.3027 - 2.299 0.303 - 141.4 1 2 0 -0.0003 10 0 0 0 1.38E+07 1.26E+07 - - - 4.3492 0.9996 221125_WJC_METTL3_EV_vs_WT_F02.15535.15535.2 0.00284 16-Nov K.QTALVELVK.H "sp|P02768|ALBU_HUMAN,tr|A0A087WWT3|A0A087WWT3_HUMAN,tr|B7WNR0|B7WNR0_HUMAN,tr|H0YA55|H0YA55_HUMAN,tr|A0A0C4DGB6|A0A0C4DGB6_HUMAN,tr|D6RHD5|D6RHD5_HUMAN,tr|C9JKR2|C9JKR2_HUMAN" 7 999.5964 77.56 15354 15535 2 999.595698 500.8055 Albumin OS=Homo sapiens OX=9606 GN=ALB PE=1 SV=2 6 2994 - 2.65E+06 - - - -0.7493 - 1.889 0.33 - 367.9 1 2 0 -0.0007 9 0 0 0 1.86E+08 2.40E+06 - - - 3.3183 0.9995 221125_WJC_METTL3_EV_vs_WT_F02.15536.15536.2 0.00389 20-Nov K.LFAIEEETTTR.H "sp|Q9UHD2|TBK1_HUMAN,tr|A0A7I2V646|A0A7I2V646_HUMAN,tr|A0A7I2V4Z2|A0A7I2V4Z2_HUMAN,tr|A0A494C079|A0A494C079_HUMAN,tr|A0A494C045|A0A494C045_HUMAN,tr|A0A494C1M6|A0A494C1M6_HUMAN,tr|A0A494C0A8|A0A494C0A8_HUMAN,tr|F5H1A3|F5H1A3_HUMAN,tr|A0A494C1I2|A0A494C1I2_HUMAN,tr|A0A7I2V4W4|A0A7I2V4W4_HUMAN,tr|F5H206|F5H206_HUMAN,tr|A0A7I2V463|A0A7I2V463_HUMAN,tr|F5GZI4|F5GZI4_HUMAN,tr|A0A494C148|A0A494C148_HUMAN,tr|A0A494C0X2|A0A494C0X2_HUMAN,tr|A0A494C167|A0A494C167_HUMAN,tr|A0A7I2V2F4|A0A7I2V2F4_HUMAN,tr|A0A494C0R4|A0A494C0R4_HUMAN,tr|A0A7I2V643|A0A7I2V643_HUMAN" 19 1308.6561 2.38 15355 15536 2 1308.658271 655.3353 Serine\threonine-protein kinase TBK1 OS=Homo sapiens OX=9606 GN=TBK1 PE=1 SV=1 4.25 2994.1 - 1.51E+06 - - - 1.6238 - 1.978 0.369 - 376.8 1 2 0 0.0021 11 0 0 0 2.20E+07 9.24E+06 - - - 3.611 0.9989 221125_WJC_METTL3_EV_vs_WT_F02.15537.15537.2 0.0745 14-Jul K.DILIQYDR[166.11].T "sp|P62249|RS16_HUMAN,tr|M0R210|M0R210_HUMAN" 2 1044.5479 0.92 15356 15537 2 1044.547813 523.2812 40S ribosomal protein S16 OS=Homo sapiens OX=9606 GN=RPS16 PE=1 SV=2 4.21 2994.1 - 4.96E+07 - - - -0.112 - 1.551 0.263 - 195.3 1 2 0 -0.0001 8 0 0 0 7.16E+08 7.80E+08 - - - 2.3072 0.9992 221125_WJC_METTL3_EV_vs_WT_F02.15538.15538.2 0.00514 18-Aug R.LEAMC[160.03]FDGVK.R "sp|P47813|IF1AX_HUMAN,tr|X6RAC9|X6RAC9_HUMAN" 2 1168.5257 0.64 15357 15538 2 1168.525267 585.2701 "Eukaryotic translation initiation factor 1A, X-chromosomal OS=Homo sapiens OX=9606 GN=EIF1AX PE=1 SV=2" 4.37 2994.2 - 6.41E+06 - - - -0.3423 - 1.2 0.407 - 137.5 1 2 0 -0.0004 10 0 0 0 1.52E+08 2.37E+08 - - - 2.5559 0.9954 221125_WJC_METTL3_EV_vs_WT_F02.15539.15539.2 0.242 14-Aug R.TQLSLLPR.A "sp|Q15020|SART3_HUMAN,tr|A0A499FI31|A0A499FI31_HUMAN" 2 926.5549 2.07 15358 15539 2 926.553798 464.2847 Squamous cell carcinoma antigen recognized by T-cells 3 OS=Homo sapiens OX=9606 GN=SART3 PE=1 SV=1 9.41 2994.2 - 2.77E+06 - - - -1.2066 - 1.584 0.127 - 361.3 1 2 0 -0.0011 8 0 0 0 1.13E+08 5.46E+07 - - - 1.3659 0.9999 221125_WJC_METTL3_EV_vs_WT_F02.15540.15540.2 0.000239 13/20 K.AGDPVILYVNK.V "sp|O15321|TM9S1_HUMAN,tr|E9PJC4|E9PJC4_HUMAN,tr|E9PSI1|E9PSI1_HUMAN,tr|E9PL78|E9PL78_HUMAN,tr|E9PJM1|E9PJM1_HUMAN,tr|E9PS99|E9PS99_HUMAN,tr|E9PQY7|E9PQY7_HUMAN,tr|E9PMQ9|E9PMQ9_HUMAN" 8 1187.655 1.1 15359 15540 2 1187.655183 594.8348 Transmembrane 9 superfamily member 1 OS=Homo sapiens OX=9606 GN=TM9SF1 PE=2 SV=2 5.88 2994.4 - 1.45E+06 - - - 0.1339 - 2.632 0.517 - 722.9 1 2 0 0.0002 11 0 0 0 6.52E+07 5.94E+07 - - - 5.4775 0.9995 221125_WJC_METTL3_EV_vs_WT_F02.15541.15541.2 0.000152 16-Oct R.VEFVIETAR[166.11].Q sp|Q7Z5L9|I2BP2_HUMAN 1 1072.5792 2.09 15360 15541 2 1072.58166 537.2969 Interferon regulatory factor 2-binding protein 2 OS=Homo sapiens OX=9606 GN=IRF2BP2 PE=1 SV=2 4.53 2994.4 - 1.12E+06 - - - 2.2656 - 2.067 0.412 - 581.6 1 2 0 0.0024 9 0 0 0 4.97E+07 2.38E+07 - - - 4.1839 0.9994 221125_WJC_METTL3_EV_vs_WT_F02.15542.15542.3 0.029 Dec-36 R.FPLSHLDALK[136.11].Q sp|Q8IUF8|RIOX2_HUMAN 1 1147.6481 1.09 15361 15542 3 1147.645373 383.5566 Ribosomal oxygenase 2 OS=Homo sapiens OX=9606 GN=RIOX2 PE=1 SV=1 6.74 2994.5 - 711985 - - - -2.3718 - 1.979 0.347 - 142.7 1 2 0 -0.0027 10 0 0 0 1.38E+07 1.26E+07 - - - 4.4014 0.9979 221125_WJC_METTL3_EV_vs_WT_F02.15543.15543.2 0.00323 20-Sep R.WVVYTTEMNGK[136.11].N "sp|Q9UI09|NDUAC_HUMAN,tr|H0YID5|H0YID5_HUMAN,tr|F8VRD8|F8VRD8_HUMAN,tr|A0A804HK60|A0A804HK60_HUMAN,tr|A0A804HHX9|A0A804HHX9_HUMAN" 5 1334.642 1.09 15362 15543 2 1334.641633 668.3283 NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 12 OS=Homo sapiens OX=9606 GN=NDUFA12 PE=1 SV=1 6 2994.6 - 495748 - - - -0.2922 - 1.678 0.196 - 148.1 2 2 0 -0.0004 11 0 0 0 1.16E+07 1.07E+07 - - - 1.7543 0.9976 221125_WJC_METTL3_EV_vs_WT_F02.15546.15546.2 0.463 16-Aug R.AGLQFPVGR.V "sp|P16104|H2AX_HUMAN,sp|Q9BTM1|H2AJ_HUMAN,sp|Q93077|H2A1C_HUMAN,sp|Q99878|H2A1J_HUMAN,sp|Q16777|H2A2C_HUMAN,sp|Q8IUE6|H2A2B_HUMAN,sp|Q96QV6|H2A1A_HUMAN,sp|P0C0S5|H2AZ_HUMAN,sp|P04908|H2A1B_HUMAN,sp|P20671|H2A1D_HUMAN,sp|P0C0S8|H2A1_HUMAN,sp|Q6FI13|H2A2A_HUMAN,sp|Q96KK5|H2A1H_HUMAN,sp|Q71UI9|H2AV_HUMAN,sp|Q7L7L0|H2A3_HUMAN,tr|A0A0U1RR32|A0A0U1RR32_HUMAN,tr|A0A0U1RRH7|A0A0U1RRH7_HUMAN,tr|A0A3B3IS11|A0A3B3IS11_HUMAN,tr|C9J0D1|C9J0D1_HUMAN,tr|A0A494C189|A0A494C189_HUMAN" 20 943.524 1.16 15364 15546 2 943.523529 472.7693 Histone H2AX OS=Homo sapiens OX=9606 GN=H2AX PE=1 SV=2 9.79 2995 - 1.76E+06 - - - -0.4462 - 1.724 0.141 - 187.2 1 2 0 -0.0004 9 0 0 0 1.35E+10 1.16E+10 - - - 1.658 0.9955 221125_WJC_METTL3_EV_vs_WT_F02.15548.15548.2 0.138 16-Aug R.GLFDEYGSK.K "sp|Q58FF3|ENPLL_HUMAN,sp|P14625|ENPL_HUMAN,tr|A0A7P0T917|A0A7P0T917_HUMAN,tr|A0A7P0T823|A0A7P0T823_HUMAN,tr|A0A7P0TAE1|A0A7P0TAE1_HUMAN,tr|H0YIV0|H0YIV0_HUMAN,tr|A0A7P0TAY2|A0A7P0TAY2_HUMAN,tr|A0A087WT78|A0A087WT78_HUMAN,tr|A0A7P0TBC2|A0A7P0TBC2_HUMAN,tr|A0A7P0TAT8|A0A7P0TAT8_HUMAN" 10 1014.4658 0.83 15365 15548 2 1014.466002 508.2402 Putative endoplasmin-like protein OS=Homo sapiens OX=9606 GN=HSP90B2P PE=5 SV=1 4.37 2995.2 - 2.12E+06 - - - 0.1735 - 1.175 0.227 - 116.3 1 2 0 0.0002 9 0 0 0 3.27E+07 3.96E+07 - - - 1.1841 0.9992 221125_WJC_METTL3_EV_vs_WT_F02.15549.15549.2 0.0137 14-Aug K.LGNFFSPK.V "sp|P46940|IQGA1_HUMAN,tr|A0A0J9YXZ5|A0A0J9YXZ5_HUMAN" 2 908.4756 0.75 15366 15549 2 908.475105 455.2451 Ras GTPase-activating-like protein IQGAP1 OS=Homo sapiens OX=9606 GN=IQGAP1 PE=1 SV=1 8.75 2995.3 - 1.86E+06 - - - -0.5482 - 1.455 0.337 - 144 1 2 0 -0.0005 8 0 0 0 3.36E+07 4.49E+07 - - - 2.6609 0.9994 221125_WJC_METTL3_EV_vs_WT_F02.15551.15551.2 0.258 24-Nov K.IAVEPVNPSELPK[136.11].M sp|Q15029|U5S1_HUMAN 1 1399.7802 2.34 15368 15551 2 1399.779465 700.8974 116 kDa U5 small nuclear ribonucleoprotein component OS=Homo sapiens OX=9606 GN=EFTUD2 PE=1 SV=1 4.53 2995.5 - 1.47E+06 - - - -0.5472 - 2.217 0.248 - 369.5 1 2 0 -0.0008 13 0 0 0 1.58E+08 6.75E+07 - - - 2.9158 0.9962 221125_WJC_METTL3_EV_vs_WT_F02.15552.15552.2 0.0345 14-Aug K.WLC[160.03]PLSGK[136.11].K "sp|Q9BXP5|SRRT_HUMAN,tr|H7C3A1|H7C3A1_HUMAN" 2 967.5041 0.01 15369 15552 2 967.503917 484.7593 Serrate RNA effector molecule homolog OS=Homo sapiens OX=9606 GN=SRRT PE=1 SV=1 8.22 2995.6 - 1.17E+06 - - - -0.1612 - 1.452 0.152 - 225.2 1 2 0 -0.0002 8 0 0 0 2.95E+05 2.06E+07 - - - 1.2884 0.9975 221125_WJC_METTL3_EV_vs_WT_F02.15553.15553.2 0.986 14-Jul R.DSILSEMK.M sp|Q9UQE7|SMC3_HUMAN 1 921.4477 0.89 15370 15553 2 921.448117 461.7311 Structural maintenance of chromosomes protein 3 OS=Homo sapiens OX=9606 GN=SMC3 PE=1 SV=2 4.37 2995.7 - 1.11E+06 - - - 0.4167 - 1.336 0.237 - 124.7 1 2 0 0.0004 8 0 0 0 1.90E+07 2.14E+07 - - - 1.665 0.9996 221125_WJC_METTL3_EV_vs_WT_F02.15557.15557.2 0.00239 16-Sep K.GYGFIEYEK[136.11].A "sp|Q9UHX1|PUF60_HUMAN,tr|A0A0J9YYL3|A0A0J9YYL3_HUMAN,tr|A0A0J9YWM1|A0A0J9YWM1_HUMAN,tr|H0YEM1|H0YEM1_HUMAN,tr|A0A0J9YVR6|A0A0J9YVR6_HUMAN,tr|A0A0J9YXX5|A0A0J9YXX5_HUMAN,tr|A0A0J9YXJ8|A0A0J9YXJ8_HUMAN,tr|E9PQ56|E9PQ56_HUMAN,tr|H0YCP8|H0YCP8_HUMAN,tr|A0A0J9YVP6|A0A0J9YVP6_HUMAN" 10 1112.527 1.37 15373 15557 2 1112.526056 557.2708 Poly(U)-binding-splicing factor PUF60 OS=Homo sapiens OX=9606 GN=PUF60 PE=1 SV=1 4.53 2996.2 - 2.17E+06 - - - -0.8278 - 1.694 0.389 - 248.8 1 2 0 -0.0009 9 0 0 0 1.08E+08 7.85E+07 - - - 3.4388 0.9916 221125_WJC_METTL3_EV_vs_WT_F02.15559.15559.2 5.15E-05 24-Nov H.SLTPVAQADPLVR[166.11].R "sp|Q14444|CAPR1_HUMAN,tr|G3V153|G3V153_HUMAN" 2 1375.7699 0.95 15374 15559 2 1375.769379 688.8922 Caprin-1 OS=Homo sapiens OX=9606 GN=CAPRIN1 PE=1 SV=2 5.55 2996.4 - 1.20E+07 - - - -0.3678 - 2.397 0.451 - 394.5 1 1 0 -0.0005 13 0 0 0 2.22E+08 2.33E+08 - - - 4.6156 0.9998 221125_WJC_METTL3_EV_vs_WT_F02.15561.15561.3 0.000121 Nov-40 K.IWTHPGWSPLK[136.11].T sp|O43172|PRP4_HUMAN 1 1328.7121 2.47 15376 15561 3 1328.711066 443.9113 U4\U6 small nuclear ribonucleoprotein Prp4 OS=Homo sapiens OX=9606 GN=PRPF4 PE=1 SV=2 8.76 2996.5 - 2.21E+06 - - - -0.7722 - 2.237 0.355 - 222.3 1 2 0 -0.001 11 0 0 0 1.06E+08 4.30E+07 - - - 4.7849 0.9724 221125_WJC_METTL3_EV_vs_WT_F02.15562.15562.2 0.00769 20-Jul R.AEQDSTTVAAF.A "sp|Q86U44|MTA70_HUMAN,tr|F5H6D8|F5H6D8_HUMAN,tr|H0YFV6|H0YFV6_HUMAN,tr|B4DTN4|B4DTN4_HUMAN" 4 1138.5142 - 15377 15562 2 1138.51414 570.2644 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 3.67 2996.6 - 1.92E+06 - - - -0.0817 - 1.336 0.44 - 129.3 1 1 0 -0.0001 11 0 0 0 - - - - - 3.0745 0.9999 221125_WJC_METTL3_EV_vs_WT_F02.15563.15563.3 0.00777 14/44 K.SPILVATAVAAR.G "sp|O00571|DDX3X_HUMAN,sp|O15523|DDX3Y_HUMAN,tr|A0A2R8YFR4|A0A2R8YFR4_HUMAN,tr|A0A2R8YCW1|A0A2R8YCW1_HUMAN,tr|A0A2R8YDT5|A0A2R8YDT5_HUMAN,tr|A0A2R8Y645|A0A2R8Y645_HUMAN,tr|A0A2R8YF78|A0A2R8YF78_HUMAN,tr|A0A0D9SFB3|A0A0D9SFB3_HUMAN,tr|A0A2R8YFS5|A0A2R8YFS5_HUMAN,tr|A0A0D9SF53|A0A0D9SF53_HUMAN,tr|A0A087WVZ1|A0A087WVZ1_HUMAN,tr|A0A0J9YVQ7|A0A0J9YVQ7_HUMAN,tr|A0A2R8Y5G6|A0A2R8Y5G6_HUMAN,tr|A0A2R8Y7T2|A0A2R8Y7T2_HUMAN,tr|A0A0D9SG12|A0A0D9SG12_HUMAN,tr|F6S8Q4|F6S8Q4_HUMAN,tr|A0A2U3TZJ9|A0A2U3TZJ9_HUMAN,tr|A0A2R8Y4A4|A0A2R8Y4A4_HUMAN" 18 1167.6976 1.29 15378 15563 3 1167.696819 390.2398 ATP-dependent RNA helicase DDX3X OS=Homo sapiens OX=9606 GN=DDX3X PE=1 SV=3 9.47 2996.7 - 894311 - - - -0.6329 - 2.305 0.372 - 326 1 2 0 -0.0007 12 0 0 0 2.00E+07 1.56E+07 - - - 5.0019 0.9995 221125_WJC_METTL3_EV_vs_WT_F02.15565.15565.2 0.00185 20-Oct K.LWTGGLDNTVR.S "sp|Q04727|TLE4_HUMAN,sp|Q04725|TLE2_HUMAN,sp|Q04724|TLE1_HUMAN,sp|Q04726|TLE3_HUMAN,tr|A0A0D9SES8|A0A0D9SES8_HUMAN,tr|H0YL70|H0YL70_HUMAN,tr|H0YKN8|H0YKN8_HUMAN,tr|H0YKT5|H0YKT5_HUMAN,tr|K7EMK7|K7EMK7_HUMAN,tr|H0YNI7|H0YNI7_HUMAN,tr|H0YNT2|H0YNT2_HUMAN,tr|K7EJR7|K7EJR7_HUMAN" 12 1230.6357 1.16 15380 15565 2 1230.636504 616.3251 Transducin-like enhancer protein 4 OS=Homo sapiens OX=9606 GN=TLE4 PE=1 SV=3 5.84 2996.9 - 840006 - - - 0.6647 - 1.81 0.334 - 334.2 1 2 0 0.0008 11 0 0 0 4.56E+07 3.94E+07 - - - 3.1128 0.9996 221125_WJC_METTL3_EV_vs_WT_F02.15566.15566.2 2.65E-06 13/20 R.WVVYTTEMNGK.N "sp|Q9UI09|NDUAC_HUMAN,tr|H0YID5|H0YID5_HUMAN,tr|F8VRD8|F8VRD8_HUMAN,tr|A0A804HK60|A0A804HK60_HUMAN,tr|A0A804HHX9|A0A804HHX9_HUMAN" 5 1326.6278 1.08 15381 15566 2 1326.630873 664.3212 NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 12 OS=Homo sapiens OX=9606 GN=NDUFA12 PE=1 SV=1 6 2997.1 - 779931 - - - 2.2991 - 2.284 0.442 - 485.9 1 2 0 0.003 11 0 0 0 1.16E+07 1.07E+07 - - - 4.539 0.9999 221125_WJC_METTL3_EV_vs_WT_F02.15567.15567.2 0.000169 20-Nov K.LWTGGLDNTVR[166.11].S "sp|Q04727|TLE4_HUMAN,sp|Q04725|TLE2_HUMAN,sp|Q04724|TLE1_HUMAN,sp|Q04726|TLE3_HUMAN,tr|A0A0D9SES8|A0A0D9SES8_HUMAN,tr|H0YL70|H0YL70_HUMAN,tr|H0YKN8|H0YKN8_HUMAN,tr|H0YKT5|H0YKT5_HUMAN,tr|K7EMK7|K7EMK7_HUMAN,tr|H0YNI7|H0YNI7_HUMAN,tr|H0YNT2|H0YNT2_HUMAN,tr|K7EJR7|K7EJR7_HUMAN" 12 1240.644 1.18 15382 15567 2 1240.644452 621.3293 Transducin-like enhancer protein 4 OS=Homo sapiens OX=9606 GN=TLE4 PE=1 SV=3 5.84 2997.2 - 779243 - - - 0.3998 - 2.303 0.505 - 360.9 1 2 0 0.0005 11 0 0 0 4.58E+07 3.90E+07 - - - 5.0275 0.9986 221125_WJC_METTL3_EV_vs_WT_F02.15568.15568.2 0.00336 20-Nov K.IWTHPGWSPLK.T sp|O43172|PRP4_HUMAN 1 1320.6979 2.21 15383 15568 2 1320.695204 661.3562 U4\U6 small nuclear ribonucleoprotein Prp4 OS=Homo sapiens OX=9606 GN=PRPF4 PE=1 SV=2 8.76 2997.3 - 538478 - - - -2.0353 - 1.936 0.262 - 352 1 2 0 -0.0027 11 0 0 0 1.16E+07 5.27E+06 - - - 2.7624 0.9977 221125_WJC_METTL3_EV_vs_WT_F02.15569.15569.3 0.000209 Oct-36 R.WVFKEEGVLR.V "sp|P39656|OST48_HUMAN,tr|A0A0C4DGS1|A0A0C4DGS1_HUMAN" 2 1261.6819 1.24 15384 15569 3 1261.682237 421.5679 Dolichyl-diphosphooligosaccharide--protein glycosyltransferase 48 kDa subunit OS=Homo sapiens OX=9606 GN=DDOST PE=1 SV=4 6.14 2997.5 - 449409 - - - 0.2608 - 2.058 0.285 - 168.7 1 2 1 0.0003 10 0 0 0 1.96E+07 1.58E+07 - - - 3.8252 0.9999 221125_WJC_METTL3_EV_vs_WT_F02.15574.15574.2 0.00026 16-Sep R.VWQVTIGTR[166.11].- "sp|P63244|RACK1_HUMAN,tr|H0YAF8|H0YAF8_HUMAN,tr|D6RF23|D6RF23_HUMAN,tr|J3KPE3|J3KPE3_HUMAN,tr|D6RHJ5|D6RHJ5_HUMAN,tr|D6RHH4|D6RHH4_HUMAN,tr|D6RAC2|D6RAC2_HUMAN,tr|H0Y8R5|H0Y8R5_HUMAN" 8 1068.5955 1.11 15387 15574 2 1068.595235 535.3051 Receptor of activated protein C kinase 1 OS=Homo sapiens OX=9606 GN=RACK1 PE=1 SV=3 9.72 2998.1 - 3.31E+06 - - - -0.2938 - 2.299 0.492 - 370.4 1 2 0 -0.0003 9 0 0 0 1.27E+08 1.15E+08 - - - 5.0832 0.9999 221125_WJC_METTL3_EV_vs_WT_F02.15575.15575.3 0.00595 Dec-52 K.IFVGGLSPDTPEEK.L "sp|Q14103|HNRPD_HUMAN,tr|H0Y8G5|H0Y8G5_HUMAN,tr|D6RF44|D6RF44_HUMAN,tr|D6RAF8|D6RAF8_HUMAN,tr|H0YA96|H0YA96_HUMAN" 5 1487.7508 1.59 15388 15575 3 1487.751803 496.9242 Heterogeneous nuclear ribonucleoprotein D0 OS=Homo sapiens OX=9606 GN=HNRNPD PE=1 SV=1 4.14 2998.1 - 1.85E+06 - - - 0.691 - 2.099 0.388 - 172.8 1 2 0 0.001 14 0 0 0 2.98E+07 1.88E+07 - - - 4.836 0.9998 221125_WJC_METTL3_EV_vs_WT_F02.15576.15576.2 4.60E-05 20-Oct R.IFDPSPEDIAR[166.11].A "sp|Q8N3Z3|GTPB8_HUMAN,tr|F8WBY6|F8WBY6_HUMAN,tr|A0A087WUP3|A0A087WUP3_HUMAN" 3 1268.6276 1.02 15389 15576 2 1268.626849 635.3211 GTP-binding protein 8 OS=Homo sapiens OX=9606 GN=GTPBP8 PE=1 SV=1 4.03 2998.2 - 1.18E+06 - - - -0.6211 - 1.915 0.496 - 376.6 1 2 0 -0.0008 11 0 0 0 3.67E+07 3.60E+07 - - - 4.4618 0.988 221125_WJC_METTL3_EV_vs_WT_F02.15578.15578.3 0.117 Sep-36 R.WVFK[136.11]EEGVLR[166.11].V "sp|P39656|OST48_HUMAN,tr|A0A0C4DGS1|A0A0C4DGS1_HUMAN" 2 1279.7044 1.24 15391 15578 3 1279.704532 427.5754 Dolichyl-diphosphooligosaccharide--protein glycosyltransferase 48 kDa subunit OS=Homo sapiens OX=9606 GN=DDOST PE=1 SV=4 6.14 2998.4 - 781701 - - - 0.1203 - 1.946 0.194 - 126 1 2 1 0.0002 10 0 0 0 1.96E+07 1.58E+07 - - - 2.6472 0.9968 221125_WJC_METTL3_EV_vs_WT_F02.15580.15580.2 0.491 12-Aug K.SNILVFK[136.11].L sp|Q0VDF9|HSP7E_HUMAN 1 827.4996 0.49 15393 15580 2 827.499233 414.7571 Heat shock 70 kDa protein 14 OS=Homo sapiens OX=9606 GN=HSPA14 PE=1 SV=1 8.47 2998.6 - 627154 - - - -0.4918 - 1.592 0.126 - 367.7 1 2 0 -0.0004 7 0 0 0 6.81E+06 1.39E+07 - - - 1.4449 0.9774 221125_WJC_METTL3_EV_vs_WT_F02.15581.15581.2 0.0623 12-Jul K.SNILVFK.L sp|Q0VDF9|HSP7E_HUMAN 1 819.4854 0.49 15394 15581 2 819.484734 410.75 Heat shock 70 kDa protein 14 OS=Homo sapiens OX=9606 GN=HSPA14 PE=1 SV=1 8.47 2998.8 - 459733 - - - -0.8615 - 1.39 0.01 - 191.3 1 2 0 -0.0007 7 0 0 0 6.85E+06 1.41E+07 - - - 0.1581 0.9997 221125_WJC_METTL3_EV_vs_WT_F02.15585.15585.3 0.00236 Aug-40 K.IWTHPGWSPLK.T sp|O43172|PRP4_HUMAN 1 1320.6979 2.48 15396 15585 3 1320.698231 441.2399 U4\U6 small nuclear ribonucleoprotein Prp4 OS=Homo sapiens OX=9606 GN=PRPF4 PE=1 SV=2 8.76 2999.3 - 9.38E+06 - - - 0.2567 - 1.771 0.357 - 65.6 1 2 0 0.0003 11 0 0 0 1.06E+08 4.28E+07 - - - 4.1438 0.9997 221125_WJC_METTL3_EV_vs_WT_F02.15586.15586.2 0.000181 20-Aug R.IFDPSPEDIAR.A "sp|Q8N3Z3|GTPB8_HUMAN,tr|F8WBY6|F8WBY6_HUMAN,tr|A0A087WUP3|A0A087WUP3_HUMAN" 3 1258.6194 1.02 15397 15586 2 1258.618831 630.317 GTP-binding protein 8 OS=Homo sapiens OX=9606 GN=GTPBP8 PE=1 SV=1 4.03 2999.4 - 1.49E+06 - - - -0.4259 - 1.789 0.413 - 196.2 1 2 0 -0.0005 11 0 0 0 3.64E+07 3.57E+07 - - - 3.6648 0.9997 221125_WJC_METTL3_EV_vs_WT_F02.15587.15587.2 0.000889 18-Sep K.TALYVTPLDR.V "sp|Q9UFW8|CGBP1_HUMAN,tr|C9JUJ0|C9JUJ0_HUMAN" 2 1147.6237 0.66 15398 15587 2 1147.623146 574.8191 CGG triplet repeat-binding protein 1 OS=Homo sapiens OX=9606 GN=CGGBP1 PE=1 SV=2 5.5 2999.4 - 4.57E+06 - - - -0.5036 - 1.841 0.391 - 293.3 1 2 0 -0.0006 10 0 0 0 8.45E+07 1.27E+08 - - - 3.6323 0.9991 221125_WJC_METTL3_EV_vs_WT_F02.15588.15588.2 0.000346 16-Aug K.LWNTLGVC[160.03]K.Y "sp|P63244|RACK1_HUMAN,tr|H0YAM7|H0YAM7_HUMAN,tr|D6RFX4|D6RFX4_HUMAN,tr|D6RFZ9|D6RFZ9_HUMAN,tr|D6RAU2|D6RAU2_HUMAN,tr|H0YAF8|H0YAF8_HUMAN,tr|D6R9Z1|D6R9Z1_HUMAN,tr|J3KPE3|J3KPE3_HUMAN,tr|D6R9L0|D6R9L0_HUMAN,tr|D6RHH4|D6RHH4_HUMAN,tr|D6RBD0|D6RBD0_HUMAN,tr|E9PD14|E9PD14_HUMAN,tr|H0Y8W2|H0Y8W2_HUMAN" 13 1089.5641 1.06 15399 15588 2 1089.561028 545.7893 Receptor of activated protein C kinase 1 OS=Homo sapiens OX=9606 GN=RACK1 PE=1 SV=3 8.22 2999.4 - 1.08E+06 - - - -2.8204 - 1.762 0.441 - 189 1 2 0 -0.0031 9 0 0 0 6.36E+07 5.99E+07 - - - 3.936 0.9997 221125_WJC_METTL3_EV_vs_WT_F02.15589.15589.2 0.000116 13/22 R.LEAFGQGESVLK.E "sp|Q9BUK6|MSTO1_HUMAN,tr|A0A3B3IUD2|A0A3B3IUD2_HUMAN" 2 1276.6663 1.24 15400 15589 2 1276.668168 639.3404 Protein misato homolog 1 OS=Homo sapiens OX=9606 GN=MSTO1 PE=1 SV=1 4.53 2999.6 - 728729 - - - 1.4499 - 2.349 0.4 - 621.1 1 2 0 0.0019 12 0 0 0 1.18E+07 9.51E+06 - - - 4.2418 0.9997 221125_WJC_METTL3_EV_vs_WT_F02.15591.15591.2 0.00231 22-Sep K.ILLTEPPMNPTK.N "sp|P61160|ARP2_HUMAN,tr|F5H6T1|F5H6T1_HUMAN" 2 1352.7374 1.27 15402 15591 2 1352.737823 677.376 Actin-related protein 2 OS=Homo sapiens OX=9606 GN=ACTR2 PE=1 SV=1 6 2999.8 - 556231 - - - 0.3319 - 1.918 0.4 - 224.1 1 2 0 0.0004 12 0 0 0 1.46E+07 1.15E+07 - - - 3.7089 0.9989 221125_WJC_METTL3_EV_vs_WT_F02.15593.15593.2 0.00213 18-Aug K.VIMDYESLEK.A sp|P00491|PNPH_HUMAN 1 1225.59 0.46 15404 15593 2 1225.590433 613.8023 Purine nucleoside phosphorylase OS=Homo sapiens OX=9606 GN=PNP PE=1 SV=2 4.14 3000 - 512639 - - - 0.3198 - 1.355 0.334 - 139.7 1 2 0 0.0004 10 0 0 0 1.00E+07 2.17E+07 - - - 2.3558 0.9996 221125_WJC_METTL3_EV_vs_WT_F02.15594.15594.2 0.00827 18-Oct K.EIFMQVEDER[166.11].R sp|P35580|MYH10_HUMAN 1 1304.5946 0.98 15405 15594 2 1304.59502 653.3046 Myosin-10 OS=Homo sapiens OX=9606 GN=MYH10 PE=1 SV=3 4 3000.2 - 402626 - - - 0.3051 - 1.747 0.359 - 333 1 2 0 0.0004 10 0 0 0 6.72E+06 6.88E+06 - - - 3.2497 0.9999 221125_WJC_METTL3_EV_vs_WT_F02.15595.15595.2 3.02E-05 28-Nov R.VLVEPDAGAGVAVMK.F sp|P42126|ECI1_HUMAN 1 1454.7803 1.42 15406 15595 2 1454.780385 728.3974 "Enoyl-CoA delta isomerase 1, mitochondrial OS=Homo sapiens OX=9606 GN=ECI1 PE=1 SV=1" 4.37 3000.3 - 246468 - - - 0.0577 - 2.17 0.544 - 255.5 1 2 0 0.0001 15 0 0 0 3.64E+06 2.56E+06 - - - 4.9637 0.9991 221125_WJC_METTL3_EV_vs_WT_F02.15597.15597.2 0.183 14-Aug K.DILIQYDR.T "sp|P62249|RS16_HUMAN,tr|M0R210|M0R210_HUMAN" 2 1034.5397 0.92 15407 15597 2 1034.538409 518.2771 40S ribosomal protein S16 OS=Homo sapiens OX=9606 GN=RPS16 PE=1 SV=2 4.21 3000.5 - 1.25E+07 - - - -1.2092 - 1.64 0.299 - 301.3 1 2 0 -0.0013 8 0 0 0 7.16E+08 7.80E+08 - - - 2.741 0.9983 221125_WJC_METTL3_EV_vs_WT_F02.15599.15599.2 0.042 18-Sep K.GFFEGTIASK[136.11].G "sp|P53621|COPA_HUMAN,tr|A0A3B3ISC6|A0A3B3ISC6_HUMAN,tr|A0A3B3IS84|A0A3B3IS84_HUMAN,tr|A0A3B3IU89|A0A3B3IU89_HUMAN,tr|A0A3B3ITI7|A0A3B3ITI7_HUMAN,tr|A0A3B3IT15|A0A3B3IT15_HUMAN" 6 1063.543 0.3 15408 15599 2 1063.543024 532.7788 Coatomer subunit alpha OS=Homo sapiens OX=9606 GN=COPA PE=1 SV=2 6 3000.7 - 1.38E+06 - - - 0.0592 - 1.353 0.279 - 172 1 2 0 0.0001 10 0 0 0 1.72E+07 5.65E+07 - - - 1.9456 0.9976 221125_WJC_METTL3_EV_vs_WT_F02.15601.15601.2 0.0232 12-Jun K.DYSPYFK.T "sp|P02533|K1C14_HUMAN,sp|P08779|K1C16_HUMAN" 2 918.4123 200.48 15410 15601 2 918.41265 460.2134 "Keratin, type I cytoskeletal 14 OS=Homo sapiens OX=9606 GN=KRT14 PE=1 SV=4" 5.83 3000.9 - 810602 - - - 0.3441 - 1.044 0.339 - 119.5 1 2 0 0.0003 7 0 0 0 1.39E+07 6.95E+04 - - - 1.6812 0.9915 221125_WJC_METTL3_EV_vs_WT_F02.15605.15605.2 0.0005 16-Aug R.DYQAMLGVK.L sp|Q7Z794|K2C1B_HUMAN 1 1023.5059 17.65 15412 15605 2 1023.511617 512.7602 "Keratin, type II cytoskeletal 1b OS=Homo sapiens OX=9606 GN=KRT77 PE=1 SV=3" 5.83 3001.5 - 1.49E+06 - - - 5.5691 - 1.532 0.452 - 191.6 1 2 0 0.0057 9 0 0 0 1.87E+07 1.06E+06 - - - 3.6118 0.9959 221125_WJC_METTL3_EV_vs_WT_F02.15606.15606.2 0.0195 16-Aug K.LWDIGGQPR[166.11].F "sp|Q96BM9|ARL8A_HUMAN,sp|Q9NVJ2|ARL8B_HUMAN,tr|A0A087X2J2|A0A087X2J2_HUMAN" 3 1050.5486 2.09 15413 15606 2 1050.544406 526.2816 ADP-ribosylation factor-like protein 8A OS=Homo sapiens OX=9606 GN=ARL8A PE=1 SV=1 5.84 3001.5 - 1.05E+06 - - - -3.9912 - 1.699 0.348 - 238.8 1 2 0 -0.0042 9 0 0 0 3.17E+07 1.52E+07 - - - 3.1434 0.9923 221125_WJC_METTL3_EV_vs_WT_F02.15607.15607.2 0.578 18-Aug K.LFTPSPEIVK.Y sp|Q8TCS8|PNPT1_HUMAN 1 1129.6383 1.17 15414 15607 2 1129.638849 565.8264 "Polyribonucleotide nucleotidyltransferase 1, mitochondrial OS=Homo sapiens OX=9606 GN=PNPT1 PE=1 SV=2" 6 3001.6 - 856875 - - - 0.4763 - 1.393 0.12 - 162.1 1 2 0 0.0005 10 0 0 0 8.75E+06 7.45E+06 - - - 0.8524 0.994 221125_WJC_METTL3_EV_vs_WT_F02.15608.15608.2 0.645 12-Jun K.GADVWFK.E sp|P05109|S10A8_HUMAN 1 821.4072 102.24 15415 15608 2 821.407142 411.7109 Protein S100-A8 OS=Homo sapiens OX=9606 GN=S100A8 PE=1 SV=1 5.84 3001.7 - 576163 - - - -0.0572 - 1.413 0.113 - 175.7 1 2 0 0 7 0 0 0 7.50E+08 7.33E+06 - - - 0.971 0.9999 221125_WJC_METTL3_EV_vs_WT_F02.15609.15609.2 7.74E-05 22-Dec K.ILLTEPPMNPTK[136.11].N "sp|P61160|ARP2_HUMAN,tr|F5H6T1|F5H6T1_HUMAN" 2 1360.7516 1.27 15416 15609 2 1360.751438 681.3831 Actin-related protein 2 OS=Homo sapiens OX=9606 GN=ACTR2 PE=1 SV=1 6 3001.9 - 561270 - - - -0.0999 - 2.365 0.446 - 445.2 1 2 0 -0.0001 12 0 0 0 1.46E+07 1.15E+07 - - - 4.6 0.9995 221125_WJC_METTL3_EV_vs_WT_F02.15611.15611.2 0.00019 28-Nov K.VVGVPVGSALPSTVK[136.11].Q sp|Q9ULM3|YETS2_HUMAN 1 1416.8432 0.45 15418 15611 2 1416.847303 709.4289 YEATS domain-containing protein 2 OS=Homo sapiens OX=9606 GN=YEATS2 PE=1 SV=2 8.72 3002.1 - 348317 - - - 2.9199 - 2.071 0.561 - 275.8 1 2 0 0.0041 15 0 0 0 2.65E+06 5.92E+06 - - - 4.9731 0.9784 221125_WJC_METTL3_EV_vs_WT_F02.15614.15614.2 4.66 12-Jul K.DIDLLAK[136.11].N "sp|Q86U86|PB1_HUMAN,tr|H0Y5B5|H0Y5B5_HUMAN,tr|E7EVG2|E7EVG2_HUMAN" 3 794.4629 1.83 15419 15614 2 794.46262 398.2387 Protein polybromo-1 OS=Homo sapiens OX=9606 GN=PBRM1 PE=1 SV=1 4.21 3002.5 - 2.68E+06 - - - -0.3776 - 1.403 0 - 180.1 1 2 0 -0.0003 7 0 0 0 5.79E+07 3.16E+07 - - - 0.1138 0.9995 221125_WJC_METTL3_EV_vs_WT_F02.15615.15615.2 0.00284 16-Jun K.FNPFVTSDR.S "sp|Q9UNX3|RL26L_HUMAN,sp|P61254|RL26_HUMAN,tr|J3QQQ9|J3QQQ9_HUMAN,tr|E5RIT6|E5RIT6_HUMAN,tr|E5RHH1|E5RHH1_HUMAN,tr|J3QQV1|J3QQV1_HUMAN,tr|J3KSS0|J3KSS0_HUMAN,tr|J3QRC4|J3QRC4_HUMAN,tr|J3QRI7|J3QRI7_HUMAN" 9 1081.5193 1.03 15420 15615 2 1081.5206 541.7669 60S ribosomal protein L26-like 1 OS=Homo sapiens OX=9606 GN=RPL26L1 PE=1 SV=1 5.84 3002.6 - 1.47E+06 - - - 1.2399 - 1.356 0.47 - 151.1 1 2 0 0.0013 9 0 0 0 1.94E+08 1.89E+08 - - - 3.393 0.9967 221125_WJC_METTL3_EV_vs_WT_F02.15617.15617.2 0.205 16-Aug K.LSVYAALQR.Q "sp|Q15149|PLEC_HUMAN,tr|H0YDN1|H0YDN1_HUMAN" 2 1019.5764 0.58 15422 15617 2 1019.577938 510.7955 Plectin OS=Homo sapiens OX=9606 GN=PLEC PE=1 SV=3 8.75 3002.7 - 4.37E+06 - - - 1.5281 - 1.621 0.189 - 181.9 1 2 0 0.0016 9 0 0 0 1.49E+07 2.55E+07 - - - 1.8339 0.9991 221125_WJC_METTL3_EV_vs_WT_F02.15618.15618.2 0.0297 14-Sep K.ALADLIEK.E sp|O95628|CNOT4_HUMAN 1 871.5015 1.89 15423 15618 2 871.502568 436.758 CCR4-NOT transcription complex subunit 4 OS=Homo sapiens OX=9606 GN=CNOT4 PE=1 SV=3 4.37 3002.8 - 1.80E+06 - - - 1.2438 - 1.632 0.31 - 239.3 1 2 0 0.0011 8 0 0 0 5.36E+07 2.84E+07 - - - 2.8076 0.9988 221125_WJC_METTL3_EV_vs_WT_F02.15619.15619.2 0.0198 14-Aug R.TQLSLLPR[166.11].A "sp|Q15020|SART3_HUMAN,tr|A0A499FI31|A0A499FI31_HUMAN" 2 936.5632 2.75 15424 15619 2 936.564329 469.2889 Squamous cell carcinoma antigen recognized by T-cells 3 OS=Homo sapiens OX=9606 GN=SART3 PE=1 SV=1 9.41 3002.9 - 1.48E+06 - - - 1.2204 - 1.723 0.255 - 235.2 1 2 0 0.0011 8 0 0 0 1.00E+08 3.64E+07 - - - 2.565 0.9136 221125_WJC_METTL3_EV_vs_WT_F02.15621.15621.2 9.79E-05 13/24 F.INPPIGTVTPALK.L "sp|Q9BY77|PDIP3_HUMAN,tr|F6VRR5|F6VRR5_HUMAN,tr|F8WCX5|F8WCX5_HUMAN,tr|Q6R954|Q6R954_HUMAN,tr|Q8WUT1|Q8WUT1_HUMAN,tr|F8WEE2|F8WEE2_HUMAN" 6 1319.7813 2.63 15426 15621 2 1319.784844 660.8979 Polymerase delta-interacting protein 3 OS=Homo sapiens OX=9606 GN=POLDIP3 PE=1 SV=2 8.75 3003.1 - 758655 - - - 2.6951 - 2.151 0.296 - 325.9 1 1 0 0.0036 13 0 0 0 1.19E+07 4.52E+06 - - - 3.1919 0.9965 221125_WJC_METTL3_EV_vs_WT_F02.15625.15625.2 0.00032 22-Jun K.VVPC[160.03]LVTPVTGR.E "sp|O75369|FLNB_HUMAN,tr|E7EN95|E7EN95_HUMAN,tr|A0A804HK76|A0A804HK76_HUMAN,tr|A0A804HL72|A0A804HL72_HUMAN" 4 1296.7224 1.7 15430 15625 2 1296.727594 649.3685 Filamin-B OS=Homo sapiens OX=9606 GN=FLNB PE=1 SV=2 8.22 3003.6 - 515327 - - - 4.0109 - 1.545 0.431 - 117.6 1 2 0 0.0052 12 0 0 0 1.14E+07 6.72E+06 - - - 3.3674 0.9996 221125_WJC_METTL3_EV_vs_WT_F02.15629.15629.2 0.000167 24-Aug R.LYNVVVDTEVTGK[136.11].K sp|O95347|SMC2_HUMAN 1 1443.7701 0.45 15433 15629 2 1443.769061 722.8923 Structural maintenance of chromosomes protein 2 OS=Homo sapiens OX=9606 GN=SMC2 PE=1 SV=2 4.37 3004.2 - 236371 - - - -0.6926 - 1.646 0.419 - 236.1 1 2 0 -0.001 13 0 0 0 1.76E+06 3.95E+06 - - - 3.4144 1 221125_WJC_METTL3_EV_vs_WT_F02.15631.15631.3 1.05E-08 14/48 R.LVHPGVAEVVFVK[136.11].K "sp|Q9BY77|PDIP3_HUMAN,tr|F6VRR5|F6VRR5_HUMAN" 2 1400.8271 1.55 15434 15631 3 1400.828764 467.9497 Polymerase delta-interacting protein 3 OS=Homo sapiens OX=9606 GN=POLDIP3 PE=1 SV=2 6.75 3004.4 - 2.34E+06 - - - 1.1722 - 3.06 0.629 - 340.2 1 2 0 0.0016 13 0 0 0 7.11E+07 4.59E+07 - - - 8.5846 0.999 221125_WJC_METTL3_EV_vs_WT_F02.15633.15633.2 0.154 20-Oct K.YIIIGDTGVGK.S "sp|P61019|RAB2A_HUMAN,sp|Q8WUD1|RAB2B_HUMAN,tr|A0A3B3ITL1|A0A3B3ITL1_HUMAN,tr|E9PE37|E9PE37_HUMAN,tr|E9PKL7|E9PKL7_HUMAN,tr|H0YD31|H0YD31_HUMAN" 6 1134.6285 1.45 15435 15633 2 1134.629602 568.3215 Ras-related protein Rab-2A OS=Homo sapiens OX=9606 GN=RAB2A PE=1 SV=1 5.83 3004.6 - 3.75E+06 - - - 0.9933 - 1.747 0.28 - 277.7 1 2 0 0.0011 11 0 0 0 6.11E+07 4.20E+07 - - - 2.618 0.9998 221125_WJC_METTL3_EV_vs_WT_F02.15634.15634.2 5.01E-05 20-Nov K.YIIIGDTGVGK[136.11].S "sp|P61019|RAB2A_HUMAN,sp|Q8WUD1|RAB2B_HUMAN,tr|A0A3B3ITL1|A0A3B3ITL1_HUMAN,tr|E9PE37|E9PE37_HUMAN,tr|E9PKL7|E9PKL7_HUMAN,tr|H0YD31|H0YD31_HUMAN" 6 1142.6427 1.45 15436 15634 2 1142.643789 572.3286 Ras-related protein Rab-2A OS=Homo sapiens OX=9606 GN=RAB2A PE=1 SV=1 5.83 3004.7 - 3.81E+06 - - - 0.9749 - 2.084 0.498 - 391.9 1 2 0 0.0011 11 0 0 0 6.11E+07 4.20E+07 - - - 4.7053 0.9996 221125_WJC_METTL3_EV_vs_WT_F02.15635.15635.2 0.0338 16-Oct K.LDASILEDR.D "sp|Q92785|REQU_HUMAN,tr|J3KMZ8|J3KMZ8_HUMAN" 2 1030.5295 0.79 15437 15635 2 1030.531223 516.272 Zinc finger protein ubi-d4 OS=Homo sapiens OX=9606 GN=DPF2 PE=1 SV=2 4.03 3004.7 - 3.53E+06 - - - 1.6826 - 2.342 0.354 - 365.1 1 2 0 0.0017 9 0 0 0 4.23E+07 5.33E+07 - - - 4.1171 0.9964 221125_WJC_METTL3_EV_vs_WT_F02.15636.15636.2 0.146 16-Oct K.LDASILEDR[166.11].D "sp|Q92785|REQU_HUMAN,tr|J3KMZ8|J3KMZ8_HUMAN" 2 1040.5378 0.83 15438 15636 2 1040.541038 521.2762 Zinc finger protein ubi-d4 OS=Homo sapiens OX=9606 GN=DPF2 PE=1 SV=2 4.03 3004.8 - 3.23E+06 - - - 3.1513 - 2.023 0.218 - 383.1 1 2 0 0.0033 9 0 0 0 4.64E+07 5.63E+07 - - - 2.6885 0.9982 221125_WJC_METTL3_EV_vs_WT_F02.15638.15638.2 0.0664 18-Jul K.ETGYTYILPK.N sp|Q6P2Q9|PRP8_HUMAN 1 1183.6125 1.52 15440 15638 2 1183.615144 592.8135 Pre-mRNA-processing-splicing factor 8 OS=Homo sapiens OX=9606 GN=PRPF8 PE=1 SV=2 6.1 3004.9 - 1.92E+06 - - - 2.2414 - 1.409 0.372 - 150.7 1 2 0 0.0027 10 0 0 0 4.36E+07 2.88E+07 - - - 2.7448 0.9971 221125_WJC_METTL3_EV_vs_WT_F02.15640.15640.2 0.0179 12-May K.YAFFEC[160.03]K.R "sp|Q86WW8|COA5_HUMAN,tr|B9A057|B9A057_HUMAN" 2 963.416 1.31 15442 15640 2 963.417593 482.7153 Cytochrome c oxidase assembly factor 5 OS=Homo sapiens OX=9606 GN=COA5 PE=1 SV=1 5.99 3005.1 - 1.15E+06 - - - 1.612 - 1.059 0.374 - 83.6 1 2 0 0.0016 7 0 0 0 1.47E+07 1.12E+07 - - - 1.9845 0.9992 221125_WJC_METTL3_EV_vs_WT_F02.15641.15641.2 0.000177 18-Aug K.ETGYTYILPK[136.11].N sp|Q6P2Q9|PRP8_HUMAN 1 1191.6267 1.52 15443 15641 2 1191.629063 596.8206 Pre-mRNA-processing-splicing factor 8 OS=Homo sapiens OX=9606 GN=PRPF8 PE=1 SV=2 6.1 3005.1 - 1.13E+06 - - - 1.9906 - 1.52 0.436 - 167.7 1 2 0 0.0024 10 0 0 0 4.36E+07 2.88E+07 - - - 3.4293 0.9997 221125_WJC_METTL3_EV_vs_WT_F02.15645.15645.2 0.000296 18-Oct K.FLVTPQDYAR[166.11].F "sp|Q86UT8|CATAC_HUMAN,tr|E9PJ16|E9PJ16_HUMAN,tr|E9PPT8|E9PPT8_HUMAN" 3 1218.6272 1.21 15447 15645 2 1218.626212 610.3209 Centrosomal AT-AC splicing factor OS=Homo sapiens OX=9606 GN=CENATAC PE=1 SV=1 5.84 3005.6 - 600536 - - - -0.846 - 1.638 0.426 - 268.5 1 2 0 -0.001 10 0 0 0 1.19E+07 9.82E+06 - - - 3.5646 0.8046 221125_WJC_METTL3_EV_vs_WT_F02.15647.15647.2 0.000214 24-Oct F.INPPIGTVTPALK[136.11].L "sp|Q9BY77|PDIP3_HUMAN,tr|F6VRR5|F6VRR5_HUMAN,tr|F8WCX5|F8WCX5_HUMAN,tr|Q6R954|Q6R954_HUMAN,tr|Q8WUT1|Q8WUT1_HUMAN,tr|F8WEE2|F8WEE2_HUMAN" 6 1327.7955 1.92 15449 15647 2 1327.802265 664.905 Polymerase delta-interacting protein 3 OS=Homo sapiens OX=9606 GN=POLDIP3 PE=1 SV=2 8.75 3005.9 - 497480 - - - 5.1047 - 2.041 0.445 - 184.8 1 1 0 0.0068 13 0 0 0 2.97E+07 1.55E+07 - - - 4.1567 0.9994 221125_WJC_METTL3_EV_vs_WT_F02.15652.15652.2 0.000285 20-Oct K.YLQDQLSPLTR.Q "sp|Q15025|TNIP1_HUMAN,tr|E7EMV7|E7EMV7_HUMAN,tr|A0A0A0MRZ4|A0A0A0MRZ4_HUMAN,tr|H0YC17|H0YC17_HUMAN" 4 1332.7038 2.17 15454 15652 2 1332.706983 667.3592 TNFAIP3-interacting protein 1 OS=Homo sapiens OX=9606 GN=TNIP1 PE=1 SV=2 5.84 3006.6 - 228927 - - - 2.4146 - 1.963 0.447 - 421.1 1 2 0 0.0032 11 0 0 0 3.97E+06 1.83E+06 - - - 4.1661 0.9747 221125_WJC_METTL3_EV_vs_WT_F02.15654.15654.2 3.90E-06 16-Sep W.GNVGFVFTK[136.11].E "sp|Q8NHW5|RLA0L_HUMAN,sp|P05388|RLA0_HUMAN,tr|G3V210|G3V210_HUMAN,tr|F8VU65|F8VU65_HUMAN,tr|F8VWV4|F8VWV4_HUMAN,tr|F8VWS0|F8VWS0_HUMAN,tr|F8VS58|F8VS58_HUMAN,tr|F8VW21|F8VW21_HUMAN,tr|F8VZS0|F8VZS0_HUMAN,tr|F8VRK7|F8VRK7_HUMAN,tr|F8VQY6|F8VQY6_HUMAN,tr|F8VPE8|F8VPE8_HUMAN" 12 975.5269 1.09 15455 15654 2 975.527908 488.7707 60S acidic ribosomal protein P0-like OS=Homo sapiens OX=9606 GN=RPLP0P6 PE=5 SV=1 8.75 3006.8 - 5.03E+06 - - - 1.0159 - 1.908 0.349 - 350.2 1 1 0 0.001 9 0 0 0 5.40E+08 4.95E+08 - - - 3.4875 0.9899 221125_WJC_METTL3_EV_vs_WT_F02.15658.15658.2 0.674 14-Jun K.ALADLIEK[136.11].E sp|O95628|CNOT4_HUMAN 1 879.5157 1.85 15458 15658 2 879.516894 440.7651 CCR4-NOT transcription complex subunit 4 OS=Homo sapiens OX=9606 GN=CNOT4 PE=1 SV=3 4.37 3007.2 - 3.41E+06 - - - 1.3758 - 1.275 0.157 - 102.6 1 2 0 0.0012 8 0 0 0 5.97E+07 3.23E+07 - - - 0.9329 0.9995 221125_WJC_METTL3_EV_vs_WT_F02.15659.15659.2 0.0034 22-Nov K.LGVQVVITDPEK[136.11].L "sp|P17987|TCPA_HUMAN,tr|F5GZ03|F5GZ03_HUMAN,tr|F5H282|F5H282_HUMAN,tr|E7EQR6|E7EQR6_HUMAN,tr|E7ERF2|E7ERF2_HUMAN" 5 1304.7431 0.73 15459 15659 2 1304.745086 653.3788 T-complex protein 1 subunit alpha OS=Homo sapiens OX=9606 GN=TCP1 PE=1 SV=1 4.37 3007.3 - 2.81E+06 - - - 1.5091 - 1.732 0.428 - 354.3 1 2 0 0.002 12 0 0 0 1.01E+07 1.38E+07 - - - 3.6468 0.999 221125_WJC_METTL3_EV_vs_WT_F02.15660.15660.2 0.0385 14-Jul K.MPWSITEK.D "sp|Q9Y2L1|RRP44_HUMAN,tr|F2Z2C0|F2Z2C0_HUMAN,tr|G3V1J5|G3V1J5_HUMAN" 3 990.4845 1.5 15460 15660 2 990.484041 496.2495 Exosome complex exonuclease RRP44 OS=Homo sapiens OX=9606 GN=DIS3 PE=1 SV=2 5.75 3007.4 - 2.78E+06 - - - -0.416 - 1.41 0.313 - 219.1 1 2 0 -0.0004 8 0 0 0 1.24E+08 8.26E+07 - - - 2.3889 0.9988 221125_WJC_METTL3_EV_vs_WT_F02.15662.15662.2 0.00337 14-Aug K.MPWSITEK[136.11].D "sp|Q9Y2L1|RRP44_HUMAN,tr|F2Z2C0|F2Z2C0_HUMAN,tr|G3V1J5|G3V1J5_HUMAN" 3 998.4987 1.5 15462 15662 2 998.500396 500.2566 Exosome complex exonuclease RRP44 OS=Homo sapiens OX=9606 GN=DIS3 PE=1 SV=2 5.75 3007.5 - 2.43E+06 - - - 1.7456 - 1.461 0.354 - 253.9 1 2 0 0.0017 8 0 0 0 1.24E+08 8.26E+07 - - - 2.7985 0.9987 221125_WJC_METTL3_EV_vs_WT_F02.15663.15663.2 0.0184 16-Jun R.WDQSTFIGR.A "sp|Q9H9B4|SFXN1_HUMAN,sp|Q9BWM7|SFXN3_HUMAN,tr|S4R3N9|S4R3N9_HUMAN,tr|D6RFI0|D6RFI0_HUMAN,tr|D6RDG7|D6RDG7_HUMAN,tr|S4R2X2|S4R2X2_HUMAN,tr|D6RAE9|D6RAE9_HUMAN,tr|A0A1P0AYU5|A0A1P0AYU5_HUMAN" 8 1108.5302 1.16 15463 15663 2 1108.528666 555.2724 Sideroflexin-1 OS=Homo sapiens OX=9606 GN=SFXN1 PE=1 SV=4 5.84 3007.5 - 2.07E+06 - - - -1.3459 - 1.276 0.363 - 68 1 2 0 -0.0015 9 0 0 0 1.34E+07 1.15E+07 - - - 2.4268 0.9991 221125_WJC_METTL3_EV_vs_WT_F02.15664.15664.2 0.000378 16-Sep R.GDSVIVVLR.N "sp|P62316|SMD2_HUMAN,tr|K7EJB5|K7EJB5_HUMAN" 2 956.5655 1.54 15464 15664 2 956.567134 479.29 Small nuclear ribonucleoprotein Sm D2 OS=Homo sapiens OX=9606 GN=SNRPD2 PE=1 SV=1 5.84 3007.6 - 1.91E+06 - - - 1.7281 - 1.787 0.33 - 327.4 1 2 0 0.0017 9 0 0 0 1.79E+08 1.16E+08 - - - 3.1574 0.9997 221125_WJC_METTL3_EV_vs_WT_F02.15667.15667.2 0.000485 24-Dec R.LYNVVVDTEVTGK.K sp|O95347|SMC2_HUMAN 1 1435.7559 0.45 15467 15667 2 1435.75666 718.8852 Structural maintenance of chromosomes protein 2 OS=Homo sapiens OX=9606 GN=SMC2 PE=1 SV=2 4.37 3007.9 - 718507 - - - 0.5565 - 2.187 0.388 - 272.8 1 2 0 0.0008 13 0 0 0 1.76E+06 3.95E+06 - - - 3.9149 0.985 221125_WJC_METTL3_EV_vs_WT_F02.15673.15673.2 0.00865 18-Oct R.VSALEVLPDR.V sp|Q9Y657|SPIN1_HUMAN 1 1097.6081 2.46 15471 15673 2 1097.615651 549.8113 Spindlin-1 OS=Homo sapiens OX=9606 GN=SPIN1 PE=1 SV=3 4.37 3008.7 - 3.03E+06 - - - 6.9032 - 2.35 0.336 - 474.5 1 2 0 0.0076 10 0 0 0 3.29E+08 1.34E+08 - - - 3.9052 0.9999 221125_WJC_METTL3_EV_vs_WT_F02.15674.15674.2 3.33E-07 20-Oct K.LLYNNVSNFGR[166.11].L "sp|Q00610|CLH1_HUMAN,tr|J3KS13|J3KS13_HUMAN,tr|A0A087WVQ6|A0A087WVQ6_HUMAN" 3 1305.6705 0.82 15472 15674 2 1305.671374 653.8425 Clathrin heavy chain 1 OS=Homo sapiens OX=9606 GN=CLTC PE=1 SV=5 8.75 3008.8 - 2.16E+06 - - - 0.6656 - 2.052 0.551 - 361.4 1 2 0 0.0009 11 0 0 0 1.48E+08 1.80E+08 - - - 5.055 0.9997 221125_WJC_METTL3_EV_vs_WT_F02.15677.15677.2 7.83E-06 20-Aug K.LLYNNVSNFGR.L "sp|Q00610|CLH1_HUMAN,tr|J3KS13|J3KS13_HUMAN,tr|A0A087WVQ6|A0A087WVQ6_HUMAN" 3 1295.6622 0.82 15475 15677 2 1295.662771 648.8384 Clathrin heavy chain 1 OS=Homo sapiens OX=9606 GN=CLTC PE=1 SV=5 8.75 3008.9 - 1.53E+06 - - - 0.4137 - 1.8 0.42 - 252.8 1 2 0 0.0005 11 0 0 0 1.48E+08 1.79E+08 - - - 3.7331 0.9996 221125_WJC_METTL3_EV_vs_WT_F02.15678.15678.2 0.000291 24-Sep R.AWGPGLEGGVVGK[136.11].S "sp|P21333|FLNA_HUMAN,tr|A0A7P0NMY4|A0A7P0NMY4_HUMAN,tr|Q60FE5|Q60FE5_HUMAN" 3 1233.6597 1.17 15476 15678 2 1233.661506 617.8371 Filamin-A OS=Homo sapiens OX=9606 GN=FLNA PE=1 SV=4 6.05 3009 - 1.51E+06 - - - 1.4461 - 1.925 0.421 - 267 1 2 0 0.0018 13 0 0 0 5.43E+07 4.62E+07 - - - 3.8308 0.9998 221125_WJC_METTL3_EV_vs_WT_F02.15680.15680.2 0.000394 18-Nov K.LESDYEILER[166.11].F "sp|P41252|SYIC_HUMAN,tr|A0A804HL54|A0A804HL54_HUMAN,tr|A0A804HKU1|A0A804HKU1_HUMAN,tr|A0A804HK69|A0A804HK69_HUMAN,tr|A0A804HIV9|A0A804HIV9_HUMAN,tr|A0A804HJN6|A0A804HJN6_HUMAN,tr|A0A804HHW9|A0A804HHW9_HUMAN,tr|A0A0A0MSX9|A0A0A0MSX9_HUMAN,tr|J3KR24|J3KR24_HUMAN,tr|A0A804HIG2|A0A804HIG2_HUMAN,tr|A0A804HJ36|A0A804HJ36_HUMAN" 11 1275.6222 1.92 15478 15680 2 1275.624415 638.8184 "Isoleucine--tRNA ligase, cytoplasmic OS=Homo sapiens OX=9606 GN=IARS1 PE=1 SV=2" 4 3009.2 - 764552 - - - 1.7231 - 2.158 0.523 - 506 1 2 0 0.0022 10 0 0 0 7.53E+07 3.93E+07 - - - 5.0502 0.9991 221125_WJC_METTL3_EV_vs_WT_F02.15681.15681.2 1.25E-06 24-Nov R.SISGPSVGVMEMR[166.11].S "sp|Q8NFH5|NUP35_HUMAN,tr|C9JWU7|C9JWU7_HUMAN,tr|F8WCF5|F8WCF5_HUMAN,tr|F8WEL4|F8WEL4_HUMAN,tr|C9JIY9|C9JIY9_HUMAN,tr|C9IYQ7|C9IYQ7_HUMAN" 6 1358.6562 1.15 15479 15681 2 1358.651642 680.3354 Nucleoporin NUP35 OS=Homo sapiens OX=9606 GN=NUP35 PE=1 SV=1 5.72 3009.3 - 745505 - - - -3.3379 - 2.123 0.465 - 271.4 1 2 0 -0.0045 13 0 0 0 1.49E+07 1.30E+07 - - - 4.4062 0.9998 221125_WJC_METTL3_EV_vs_WT_F02.15682.15682.2 2.03E-06 13/24 R.SISGPSVGVMEMR.S "sp|Q8NFH5|NUP35_HUMAN,tr|C9JWU7|C9JWU7_HUMAN,tr|F8WCF5|F8WCF5_HUMAN,tr|F8WEL4|F8WEL4_HUMAN,tr|C9JIY9|C9JIY9_HUMAN,tr|C9IYQ7|C9IYQ7_HUMAN" 6 1348.6479 1.15 15480 15682 2 1348.644604 675.3312 Nucleoporin NUP35 OS=Homo sapiens OX=9606 GN=NUP35 PE=1 SV=1 5.72 3009.5 - 719905 - - - -2.4491 - 2.49 0.584 - 493.9 1 2 0 -0.0033 13 0 0 0 1.49E+07 1.30E+07 - - - 5.6948 0.9639 221125_WJC_METTL3_EV_vs_WT_F02.15683.15683.2 0.542 18-Oct K.EVTIVVLGNK.C "sp|Q9NYR9|KBRS2_HUMAN,tr|K7ERG2|K7ERG2_HUMAN" 2 1070.6336 0.61 15481 15683 2 1070.63801 536.3241 NF-kappa-B inhibitor-interacting Ras-like protein 2 OS=Homo sapiens OX=9606 GN=NKIRAS2 PE=1 SV=1 6.1 3009.6 - 695519 - - - 4.1564 - 1.536 0.153 - 243.3 1 2 0 0.0044 10 0 0 0 4.06E+06 6.69E+06 - - - 1.3676 0.9297 221125_WJC_METTL3_EV_vs_WT_F02.15685.15685.2 0.142 20-Jul R.GGYIGSTYFER.C sp|P61081|UBC12_HUMAN 1 1248.5775 4.75 15483 15685 2 1248.570642 625.296 NEDD8-conjugating enzyme Ubc12 OS=Homo sapiens OX=9606 GN=UBE2M PE=1 SV=1 6 3009.8 - 635152 - - - -5.4943 - 1.13 0.294 - 106.8 1 2 0 -0.0069 11 0 0 0 3.37E+06 7.09E+05 - - - 1.541 0.9995 221125_WJC_METTL3_EV_vs_WT_F02.15688.15688.2 0.000987 16-Jul R.EYQDLLNVK.M "sp|P08670|VIME_HUMAN,sp|P14136|GFAP_HUMAN,sp|P17661|DESM_HUMAN,sp|Q16352|AINX_HUMAN,sp|P07197|NFM_HUMAN,sp|P12036|NFH_HUMAN,sp|P07196|NFL_HUMAN,tr|A0A1W2PR46|A0A1W2PR46_HUMAN,tr|A0A1X7SBR3|A0A1X7SBR3_HUMAN,tr|K7EJU1|K7EJU1_HUMAN,tr|A0A1X7SCE1|A0A1X7SCE1_HUMAN,tr|A0A1W2PRT3|A0A1W2PRT3_HUMAN,tr|B0YJC5|B0YJC5_HUMAN,tr|B0YJC4|B0YJC4_HUMAN,tr|E7ESP9|E7ESP9_HUMAN,tr|E7EMV2|E7EMV2_HUMAN" 16 1120.5764 1.27 15485 15688 2 1120.577039 561.2955 Vimentin OS=Homo sapiens OX=9606 GN=VIM PE=1 SV=4 4.37 3010.1 - 1.40E+06 - - - 0.5345 - 1.406 0.413 - 199.9 1 2 0 0.0006 9 0 0 0 3.51E+07 2.77E+07 - - - 3.077 0.9998 221125_WJC_METTL3_EV_vs_WT_F02.15690.15690.2 0.164 18-Nov R.LSQTLSLVPR[166.11].L "sp|O94766|B3GA3_HUMAN,tr|G3V150|G3V150_HUMAN,tr|E9PNA1|E9PNA1_HUMAN" 3 1122.6636 1.29 15486 15690 2 1122.665355 562.3391 Galactosylgalactosylxylosylprotein 3-beta-glucuronosyltransferase 3 OS=Homo sapiens OX=9606 GN=B3GAT3 PE=1 SV=2 9.75 3010.4 - 1.57E+06 - - - 1.5374 - 2.445 0.426 - 491.4 1 2 0 0.0017 10 0 0 0 3.99E+07 3.10E+07 - - - 4.6824 0.7833 221125_WJC_METTL3_EV_vs_WT_F02.15692.15692.2 0.911 14-Jul C.GITSPLLK[136.11].T tr|Q5TDI7|Q5TDI7_HUMAN 1 835.5259 1.37 15488 15692 2 835.525421 418.7702 TAF5-like RNA polymerase II p300\CBP-associated factor-associated factor 65 kDa subunit 5L OS=Homo sapiens OX=9606 GN=TAF5L PE=1 SV=1 8.75 3010.7 - 820766 - - - -0.5182 - 1.257 0.197 - 150.5 1 1 0 -0.0004 8 0 0 0 1.54E+08 1.12E+08 - - - 1.1857 0.9993 221125_WJC_METTL3_EV_vs_WT_F02.15694.15694.2 7.15E-05 26-Oct R.EPLLVTNGADNALR[166.11].L "sp|Q8NI36|WDR36_HUMAN,tr|A0A0A0MTB8|A0A0A0MTB8_HUMAN" 2 1491.7921 0.66 15490 15694 2 1491.796025 746.9033 WD repeat-containing protein 36 OS=Homo sapiens OX=9606 GN=WDR36 PE=1 SV=1 4.37 3010.9 - 461374 - - - 2.6465 - 2.109 0.441 - 255.6 1 2 0 0.0039 14 0 0 0 7.06E+06 1.06E+07 - - - 4.1696 0.8742 221125_WJC_METTL3_EV_vs_WT_F02.15695.15695.2 0.0578 26-Sep R.VYTADPYHALAPAA.S "sp|O43251|RFOX2_HUMAN,tr|B0QYV1|B0QYV1_HUMAN,tr|A0A0G2JRD1|A0A0G2JRD1_HUMAN,tr|A0A0G2JRA5|A0A0G2JRA5_HUMAN,tr|S4R3K7|S4R3K7_HUMAN" 5 1458.7143 - 15491 15695 2 1458.715582 730.3644 RNA binding protein fox-1 homolog 2 OS=Homo sapiens OX=9606 GN=RBFOX2 PE=1 SV=3 5.08 3011 - 341287 - - - 0.8583 - 1.526 0.233 - 129.8 1 1 0 0.0013 14 0 0 0 - - - - - 1.8222 0.9998 221125_WJC_METTL3_EV_vs_WT_F02.15702.15702.2 7.94E-05 18-Oct K.VLTLSDDLER.T sp|P55010|IF5_HUMAN 1 1159.6085 1.01 15496 15702 2 1159.607143 580.8115 Eukaryotic translation initiation factor 5 OS=Homo sapiens OX=9606 GN=EIF5 PE=1 SV=2 4.03 3011.9 - 5.33E+06 - - - -1.1426 - 2.215 0.462 - 428.3 1 2 0 -0.0013 10 0 0 0 6.72E+07 6.63E+07 - - - 4.6727 0.9999 221125_WJC_METTL3_EV_vs_WT_F02.15703.15703.2 2.15E-06 18-Dec K.LESDYEILER.F "sp|P41252|SYIC_HUMAN,tr|A0A804HL54|A0A804HL54_HUMAN,tr|A0A804HKU1|A0A804HKU1_HUMAN,tr|A0A804HK69|A0A804HK69_HUMAN,tr|A0A804HIV9|A0A804HIV9_HUMAN,tr|A0A804HJN6|A0A804HJN6_HUMAN,tr|A0A804HHW9|A0A804HHW9_HUMAN,tr|A0A0A0MSX9|A0A0A0MSX9_HUMAN,tr|J3KR24|J3KR24_HUMAN,tr|A0A804HIG2|A0A804HIG2_HUMAN,tr|A0A804HJ36|A0A804HJ36_HUMAN" 11 1265.6139 1.62 15497 15703 2 1265.614593 633.8142 "Isoleucine--tRNA ligase, cytoplasmic OS=Homo sapiens OX=9606 GN=IARS1 PE=1 SV=2" 4 3012 - 2.41E+06 - - - 0.5104 - 2.28 0.509 - 575.8 1 2 0 0.0006 10 0 0 0 6.26E+07 3.86E+07 - - - 5.1008 0.9993 221125_WJC_METTL3_EV_vs_WT_F02.15704.15704.2 0.182 14-Oct K.ASLLQLTR[166.11].E "tr|K7EJH0|K7EJH0_HUMAN,tr|K7EMX1|K7EMX1_HUMAN,tr|K7EJV2|K7EJV2_HUMAN,tr|K7ESQ2|K7ESQ2_HUMAN" 4 910.5475 2.34 15498 15704 2 910.547682 456.281 Kinetochore protein Spc24 (Fragment) OS=Homo sapiens OX=9606 GN=SPC24 PE=1 SV=1 9.79 3012 - 1.03E+07 - - - 0.1603 - 1.954 0.219 - 365.9 1 2 0 0.0001 8 0 0 0 3.25E+08 1.39E+08 - - - 2.6788 0.9988 221125_WJC_METTL3_EV_vs_WT_F02.15705.15705.2 0.012 14-Sep R.IWTVDDYR.L "sp|Q676U5|A16L1_HUMAN,tr|E7EVC7|E7EVC7_HUMAN" 2 1066.5084 3.01 15499 15705 2 1066.506504 534.2615 Autophagy-related protein 16-1 OS=Homo sapiens OX=9606 GN=ATG16L1 PE=1 SV=2 4.21 3012.1 - 1.77E+06 - - - -1.7403 - 1.726 0.278 - 290 1 2 0 -0.0019 8 0 0 0 1.88E+07 6.24E+06 - - - 2.7399 0.9998 221125_WJC_METTL3_EV_vs_WT_F02.15708.15708.2 0.000475 16-Sep R.AYALAFAER[166.11].G "sp|P51659|DHB4_HUMAN,tr|A0A2R8YD50|A0A2R8YD50_HUMAN,tr|A0A804HLJ0|A0A804HLJ0_HUMAN,tr|A0A804HIR1|A0A804HIR1_HUMAN,tr|E7ER27|E7ER27_HUMAN,tr|A0A2R8YF45|A0A2R8YF45_HUMAN,tr|E7EPL9|E7EPL9_HUMAN,tr|A0A804HKU2|A0A804HKU2_HUMAN,tr|A0A804HKT2|A0A804HKT2_HUMAN,tr|A0A2R8YDT8|A0A2R8YDT8_HUMAN,tr|A0A804HK65|A0A804HK65_HUMAN,tr|A0A2R8YEG2|A0A2R8YEG2_HUMAN" 12 1020.5268 0.81 15502 15708 2 1020.526338 511.2707 Peroxisomal multifunctional enzyme type 2 OS=Homo sapiens OX=9606 GN=HSD17B4 PE=1 SV=3 6.05 3012.4 - 1.15E+06 - - - -0.4537 - 1.984 0.425 - 360 1 2 0 -0.0005 9 0 0 0 2.88E+07 3.56E+07 - - - 4.162 0.9996 221125_WJC_METTL3_EV_vs_WT_F02.15709.15709.2 5.08E-05 18-Sep K.AVEDDFVEMR[166.11].K sp|Q9BTE3|MCMBP_HUMAN 1 1219.5419 3.28 15503 15709 2 1219.54342 610.7782 Mini-chromosome maintenance complex-binding protein OS=Homo sapiens OX=9606 GN=MCMBP PE=1 SV=2 3.92 3012.5 - 757695 - - - 1.2808 - 1.826 0.395 - 272.3 1 2 0 0.0016 10 0 0 0 3.58E+07 1.09E+07 - - - 3.6387 1 221125_WJC_METTL3_EV_vs_WT_F02.15710.15710.2 1.36E-07 20-Nov K.YGYTEDPLEVR.L sp|Q14966|ZN638_HUMAN 1 1340.6248 0.51 15504 15710 2 1340.623821 671.3197 Zinc finger protein 638 OS=Homo sapiens OX=9606 GN=ZNF638 PE=1 SV=2 4.14 3012.6 - 568671 - - - -0.7646 - 2.486 0.629 - 312.2 1 2 0 -0.001 11 0 0 0 1.88E+07 3.70E+07 - - - 6.1501 0.9989 221125_WJC_METTL3_EV_vs_WT_F02.15712.15712.2 0.0235 16-Sep R.AYALAFAER.G "sp|P51659|DHB4_HUMAN,tr|A0A2R8YD50|A0A2R8YD50_HUMAN,tr|A0A804HLJ0|A0A804HLJ0_HUMAN,tr|A0A804HIR1|A0A804HIR1_HUMAN,tr|E7ER27|E7ER27_HUMAN,tr|A0A2R8YF45|A0A2R8YF45_HUMAN,tr|E7EPL9|E7EPL9_HUMAN,tr|A0A804HKU2|A0A804HKU2_HUMAN,tr|A0A804HKT2|A0A804HKT2_HUMAN,tr|A0A2R8YDT8|A0A2R8YDT8_HUMAN,tr|A0A804HK65|A0A804HK65_HUMAN,tr|A0A2R8YEG2|A0A2R8YEG2_HUMAN" 12 1010.5185 0.72 15506 15712 2 1010.51557 506.2665 Peroxisomal multifunctional enzyme type 2 OS=Homo sapiens OX=9606 GN=HSD17B4 PE=1 SV=3 6.05 3012.9 - 538268 - - - -2.9302 - 1.918 0.378 - 341.5 1 2 0 -0.003 9 0 0 0 2.51E+07 3.49E+07 - - - 3.7162 0.9997 221125_WJC_METTL3_EV_vs_WT_F02.15717.15717.2 0.00265 16-Nov K.SGVGNIFIK.N "sp|Q96DU9|PABP5_HUMAN,sp|Q4VXU2|PAP1L_HUMAN,sp|P11940|PABP1_HUMAN,tr|A0A7I2YQE4|A0A7I2YQE4_HUMAN,tr|A0A7I2V649|A0A7I2V649_HUMAN,tr|A0A6Q8JFT6|A0A6Q8JFT6_HUMAN,tr|H0YAR2|H0YAR2_HUMAN,tr|E5RJB9|E5RJB9_HUMAN,tr|A0A7I2YQ88|A0A7I2YQ88_HUMAN,tr|E5RH24|E5RH24_HUMAN,tr|E5RGH3|E5RGH3_HUMAN,tr|A0A7I2YQ90|A0A7I2YQ90_HUMAN,tr|A0A7I2V4N4|A0A7I2V4N4_HUMAN,tr|A0A6Q8JFV4|A0A6Q8JFV4_HUMAN,tr|E7EQV3|E7EQV3_HUMAN" 15 933.5284 1.37 15509 15717 2 933.527251 467.7715 Polyadenylate-binding protein 5 OS=Homo sapiens OX=9606 GN=PABPC5 PE=1 SV=1 8.47 3013.4 - 3.39E+06 - - - -1.1955 - 2.153 0.368 - 321.2 1 2 0 -0.0011 9 0 0 0 1.33E+09 9.75E+08 - - - 3.9773 0.9976 221125_WJC_METTL3_EV_vs_WT_F02.15721.15721.2 0.042 18-Aug R.ATTLLEGGFR.G "sp|Q5VTB9|RN220_HUMAN,tr|Q5TDE8|Q5TDE8_HUMAN,tr|Q5TDE7|Q5TDE7_HUMAN" 3 1063.5662 1.35 15513 15721 2 1063.567268 532.7904 E3 ubiquitin-protein ligase RNF220 OS=Homo sapiens OX=9606 GN=RNF220 PE=1 SV=1 6.05 3013.9 - 533394 - - - 0.9957 - 1.493 0.232 - 131 1 2 0 0.0011 10 0 0 0 2.14E+07 1.59E+07 - - - 1.8729 0.9998 221125_WJC_METTL3_EV_vs_WT_F02.15724.15724.2 7.49E-05 24-Nov R.AWGPGLEGGVVGK.S "sp|P21333|FLNA_HUMAN,tr|A0A7P0NMY4|A0A7P0NMY4_HUMAN,tr|Q60FE5|Q60FE5_HUMAN" 3 1225.6455 1.17 15515 15724 2 1225.645427 613.83 Filamin-A OS=Homo sapiens OX=9606 GN=FLNA PE=1 SV=4 6.05 3014.2 - 3.48E+06 - - - -0.0775 - 2.206 0.426 - 415.2 1 2 0 -0.0001 13 0 0 0 5.41E+07 4.61E+07 - - - 4.218 0.9998 221125_WJC_METTL3_EV_vs_WT_F02.15726.15726.2 0.000856 16-Dec K.SGVGNIFIK[136.11].N "sp|Q96DU9|PABP5_HUMAN,sp|Q4VXU2|PAP1L_HUMAN,sp|P11940|PABP1_HUMAN,tr|A0A7I2YQE4|A0A7I2YQE4_HUMAN,tr|A0A7I2V649|A0A7I2V649_HUMAN,tr|A0A6Q8JFT6|A0A6Q8JFT6_HUMAN,tr|H0YAR2|H0YAR2_HUMAN,tr|E5RJB9|E5RJB9_HUMAN,tr|A0A7I2YQ88|A0A7I2YQ88_HUMAN,tr|E5RH24|E5RH24_HUMAN,tr|E5RGH3|E5RGH3_HUMAN,tr|A0A7I2YQ90|A0A7I2YQ90_HUMAN,tr|A0A7I2V4N4|A0A7I2V4N4_HUMAN,tr|A0A6Q8JFV4|A0A6Q8JFV4_HUMAN,tr|E7EQV3|E7EQV3_HUMAN" 15 941.5426 1.37 15516 15726 2 941.542453 471.7786 Polyadenylate-binding protein 5 OS=Homo sapiens OX=9606 GN=PABPC5 PE=1 SV=1 8.47 3014.4 - 9.31E+06 - - - -0.1211 - 2.177 0.374 - 390.6 1 2 0 -0.0001 9 0 0 0 1.33E+09 9.75E+08 - - - 4.054 0.9997 221125_WJC_METTL3_EV_vs_WT_F02.15731.15731.2 0.00175 16-Oct R.WEEVQSYIR[166.11].K sp|Q86UP2|KTN1_HUMAN 1 1218.5909 2.54 15521 15731 2 1218.590856 610.3027 Kinectin OS=Homo sapiens OX=9606 GN=KTN1 PE=1 SV=1 4.53 3014.9 - 563281 - - - -0.0016 - 1.868 0.39 - 306.4 1 2 0 0 9 0 0 0 2.93E+07 1.15E+07 - - - 3.7293 0.9996 221125_WJC_METTL3_EV_vs_WT_F02.15733.15733.2 4.35E-05 24-Aug R.VLDDGELLVQQTK[136.11].N "sp|P46459|NSF_HUMAN,tr|I3L0N3|I3L0N3_HUMAN" 2 1464.7915 3 15523 15733 2 1464.788745 733.403 Vesicle-fusing ATPase OS=Homo sapiens OX=9606 GN=NSF PE=1 SV=3 4.03 3015.1 - 229510 - - - -1.8972 - 1.733 0.513 - 140 1 2 0 -0.0028 13 0 0 0 4.52E+06 1.50E+06 - - - 4.2404 0.9995 221125_WJC_METTL3_EV_vs_WT_F02.15736.15736.2 0.0017 16-Oct K.SNIDALLSR[166.11].L "sp|Q9UKM9|RALY_HUMAN,tr|Q5QPM0|Q5QPM0_HUMAN,tr|Q5QPL9|Q5QPL9_HUMAN" 3 997.5432 1.09 15524 15736 2 997.542577 499.7789 RNA-binding protein Raly OS=Homo sapiens OX=9606 GN=RALY PE=1 SV=1 5.55 3015.6 - 4.79E+06 - - - -0.6035 - 2.024 0.264 - 511.8 1 2 0 -0.0006 9 0 0 0 1.07E+08 9.86E+07 - - - 3.0305 0.9944 221125_WJC_METTL3_EV_vs_WT_F02.15738.15738.2 0.00051 13/22 K.NVLLLGEDGAGK.T sp|Q9Y6G9|DC1L1_HUMAN 1 1184.6401 0.87 15526 15738 2 1184.645467 593.3273 Cytoplasmic dynein 1 light intermediate chain 1 OS=Homo sapiens OX=9606 GN=DYNC1LI1 PE=1 SV=3 4.37 3015.7 - 1.42E+06 - - - 4.5288 - 2.429 0.255 - 610 1 2 0 0.0054 12 0 0 0 1.86E+07 2.13E+07 - - - 3.2579 0.9997 221125_WJC_METTL3_EV_vs_WT_F02.15739.15739.2 1.11 13/22 K.NVLLLGEDGAGK[136.11].T sp|Q9Y6G9|DC1L1_HUMAN 1 1192.6543 0.85 15527 15739 2 1192.654177 597.3344 Cytoplasmic dynein 1 light intermediate chain 1 OS=Homo sapiens OX=9606 GN=DYNC1LI1 PE=1 SV=3 4.37 3015.8 - 1.34E+06 - - - -0.1048 - 2.633 0.293 - 605.9 1 2 0 -0.0001 12 0 0 0 1.81E+07 2.13E+07 - - - 3.7524 0.9995 221125_WJC_METTL3_EV_vs_WT_F02.15740.15740.2 2.73E-05 16-Nov R.WEEVQSYIR.K sp|Q86UP2|KTN1_HUMAN 1 1208.5826 2.54 15528 15740 2 1208.580318 605.2986 Kinectin OS=Homo sapiens OX=9606 GN=KTN1 PE=1 SV=1 4.53 3015.9 - 1.30E+06 - - - -1.8782 - 2.033 0.354 - 631.1 1 2 0 -0.0023 9 0 0 0 2.93E+07 1.15E+07 - - - 3.7076 0.9927 221125_WJC_METTL3_EV_vs_WT_F02.15742.15742.2 1.65 16-Oct R.AGVIFPVGR[166.11].L "sp|Q9P0M6|H2AW_HUMAN,sp|O75367|H2AY_HUMAN,tr|A0A7I2YQD6|A0A7I2YQD6_HUMAN,tr|B4DJC3|B4DJC3_HUMAN,tr|A0A7I2V412|A0A7I2V412_HUMAN,tr|Q5SQT3|Q5SQT3_HUMAN,tr|A0A7I2V423|A0A7I2V423_HUMAN,tr|A0A7I2V2N7|A0A7I2V2N7_HUMAN,tr|A0A7I2V4D9|A0A7I2V4D9_HUMAN,tr|D6RCF2|D6RCF2_HUMAN,tr|A0A7I2V6E9|A0A7I2V6E9_HUMAN,tr|A0A7I2YQB9|A0A7I2YQB9_HUMAN,tr|A0A7I2YQR8|A0A7I2YQR8_HUMAN" 13 924.5421 1.42 15530 15742 2 924.542574 463.2783 Core histone macro-H2A.2 OS=Homo sapiens OX=9606 GN=MACROH2A2 PE=1 SV=3 9.79 3016.1 - 959464 - - - 0.5592 - 1.563 0.078 - 429.5 1 2 0 0.0005 9 0 0 0 3.96E+07 2.79E+07 - - - 0.909 0.997 221125_WJC_METTL3_EV_vs_WT_F02.15744.15744.2 0.285 14-Aug R.HLFFTVPR.V "sp|Q9Y4A5|TRRAP_HUMAN,tr|A0A2R8YFJ4|A0A2R8YFJ4_HUMAN,tr|H0Y4W2|H0Y4W2_HUMAN,tr|F2Z2U4|F2Z2U4_HUMAN" 4 1015.5603 1.08 15532 15744 2 1015.560922 508.7874 Transformation\transcription domain-associated protein OS=Homo sapiens OX=9606 GN=TRRAP PE=1 SV=3 9.76 3016.4 - 514691 - - - 0.577 - 1.434 0.195 - 176 1 2 0 0.0006 8 0 0 0 1.50E+07 1.39E+07 - - - 1.5682 0.9999 221125_WJC_METTL3_EV_vs_WT_F02.15745.15745.2 6.03E-07 26-Dec K.IFVGGLNPEATEEK[136.11].L "tr|D6R9P3|D6R9P3_HUMAN,tr|D6RD18|D6RD18_HUMAN,tr|D6RBZ0|D6RBZ0_HUMAN" 3 1510.7759 1.49 15533 15745 2 1510.77527 756.3952 Heterogeneous nuclear ribonucleoprotein A\B OS=Homo sapiens OX=9606 GN=HNRNPAB PE=1 SV=1 4.25 3016.5 - 374535 - - - -0.3998 - 2.528 0.584 - 316.8 1 2 0 -0.0006 14 0 0 0 7.23E+08 4.87E+08 - - - 5.6816 0.9998 221125_WJC_METTL3_EV_vs_WT_F02.15748.15748.2 0.000853 28-Oct R.GALQNIIPASTGAAK[136.11].A "sp|P04406|G3P_HUMAN,tr|E7EUT5|E7EUT5_HUMAN" 2 1418.7973 1.68 15536 15748 2 1418.796654 710.4059 Glyceraldehyde-3-phosphate dehydrogenase OS=Homo sapiens OX=9606 GN=GAPDH PE=1 SV=3 8.75 3016.9 - 222261 - - - -0.4398 - 2.179 0.444 - 179.2 1 2 0 -0.0006 15 0 0 0 5.50E+07 3.27E+07 - - - 4.2351 0.9996 221125_WJC_METTL3_EV_vs_WT_F02.15751.15751.2 0.128 12-Jul R.MTLDDFR.L "sp|P35527|K1C9_HUMAN,tr|K7EQQ3|K7EQQ3_HUMAN" 2 896.4062 32235.65 15537 15751 2 896.406073 449.2104 "Keratin, type I cytoskeletal 9 OS=Homo sapiens OX=9606 GN=KRT9 PE=1 SV=3" 4.21 3017.3 - 6.66E+07 - - - -0.145 - 1.583 0.375 - 275.4 1 2 0 -0.0001 7 0 0 0 1.09E+10 3.37E+05 - - - 3.2661 0.9996 221125_WJC_METTL3_EV_vs_WT_F02.15752.15752.2 0.109 20-Nov K.ILIIGESGVGK[136.11].S "sp|Q9NP72|RAB18_HUMAN,tr|A0A804HIB9|A0A804HIB9_HUMAN,tr|A0A804HKV1|A0A804HKV1_HUMAN,tr|Q5W0J0|Q5W0J0_HUMAN,tr|A0A804HIM2|A0A804HIM2_HUMAN,tr|A0A087X163|A0A087X163_HUMAN,tr|B7Z4P9|B7Z4P9_HUMAN,tr|A0A804HJ83|A0A804HJ83_HUMAN,tr|A0A804HK95|A0A804HK95_HUMAN,tr|A0A804HLG5|A0A804HLG5_HUMAN" 10 1092.6634 0.98 15538 15752 2 1092.662365 547.339 Ras-related protein Rab-18 OS=Homo sapiens OX=9606 GN=RAB18 PE=1 SV=1 6 3017.4 - 3.29E+06 - - - -0.9573 - 2.326 0.289 - 301 1 2 0 -0.001 11 0 0 0 4.16E+07 4.25E+07 - - - 3.4589 0.9906 221125_WJC_METTL3_EV_vs_WT_F02.15753.15753.2 0.0122 16-Jul R.AQVQEFC[160.03]DY.G "sp|Q86U44|MTA70_HUMAN,tr|H0YFV6|H0YFV6_HUMAN" 2 1158.4652 - 15539 15753 2 1158.464641 580.2399 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 3.67 3017.4 - 6.59E+06 - - - -0.461 - 1.646 0.536 - 231.7 1 1 0 -0.0005 9 0 0 0 - - - - - 4.4415 0.9981 221125_WJC_METTL3_EV_vs_WT_F02.15754.15754.2 1.44 20-Sep K.ILIIGESGVGK.S "sp|Q9NP72|RAB18_HUMAN,tr|A0A804HIB9|A0A804HIB9_HUMAN,tr|A0A804HKV1|A0A804HKV1_HUMAN,tr|Q5W0J0|Q5W0J0_HUMAN,tr|A0A804HIM2|A0A804HIM2_HUMAN,tr|A0A087X163|A0A087X163_HUMAN,tr|B7Z4P9|B7Z4P9_HUMAN,tr|A0A804HJ83|A0A804HJ83_HUMAN,tr|A0A804HK95|A0A804HK95_HUMAN,tr|A0A804HLG5|A0A804HLG5_HUMAN" 10 1084.6492 0.98 15540 15754 2 1084.650972 543.3319 Ras-related protein Rab-18 OS=Homo sapiens OX=9606 GN=RAB18 PE=1 SV=1 6 3017.4 - 3.59E+06 - - - 1.6236 - 2.006 0.193 - 147.6 1 2 0 0.0018 11 0 0 0 4.16E+07 4.25E+07 - - - 2.3492 0.9996 221125_WJC_METTL3_EV_vs_WT_F02.15759.15759.2 0.00144 20-Nov K.LIEYYQQLAQK.E "sp|Q9UJW0|DCTN4_HUMAN,tr|E5RGG1|E5RGG1_HUMAN,tr|H9KVE0|H9KVE0_HUMAN,tr|E5RK21|E5RK21_HUMAN" 4 1395.7398 1.66 15545 15759 2 1395.739428 698.8772 Dynactin subunit 4 OS=Homo sapiens OX=9606 GN=DCTN4 PE=1 SV=1 6 3017.9 - 988344 - - - -0.2787 - 1.638 0.386 - 293.3 1 2 0 -0.0004 11 0 0 0 7.90E+06 4.76E+06 - - - 3.2268 0.9994 221125_WJC_METTL3_EV_vs_WT_F02.15760.15760.2 0.0894 18-Aug R.LSQTLSLVPR.L "sp|O94766|B3GA3_HUMAN,tr|G3V150|G3V150_HUMAN,tr|E9PNA1|E9PNA1_HUMAN" 3 1112.6554 1.23 15546 15760 2 1112.656897 557.335 Galactosylgalactosylxylosylprotein 3-beta-glucuronosyltransferase 3 OS=Homo sapiens OX=9606 GN=B3GAT3 PE=1 SV=2 9.75 3018 - 954349 - - - 1.3823 - 1.934 0.329 - 116.1 1 2 0 0.0015 10 0 0 0 3.80E+07 3.10E+07 - - - 3.3116 0.9993 221125_WJC_METTL3_EV_vs_WT_F02.15762.15762.2 0.00784 14-Aug K.QFFVAVER[166.11].E "sp|P38919|IF4A3_HUMAN,tr|I3L3H2|I3L3H2_HUMAN" 2 1004.5319 1.39 15548 15762 2 1004.530896 503.2732 Eukaryotic initiation factor 4A-III OS=Homo sapiens OX=9606 GN=EIF4A3 PE=1 SV=4 6 3018.2 - 613118 - - - -0.9855 - 1.577 0.333 - 215.1 1 2 0 -0.001 8 0 0 0 1.64E+08 1.18E+08 - - - 2.8741 0.9998 221125_WJC_METTL3_EV_vs_WT_F02.15764.15764.2 2.39E-05 20-Nov K.LIEYYQQLAQK[136.11].E "sp|Q9UJW0|DCTN4_HUMAN,tr|E5RGG1|E5RGG1_HUMAN,tr|H9KVE0|H9KVE0_HUMAN,tr|E5RK21|E5RK21_HUMAN" 4 1403.754 1.66 15550 15764 2 1403.755154 702.8843 Dynactin subunit 4 OS=Homo sapiens OX=9606 GN=DCTN4 PE=1 SV=1 6 3018.5 - 548791 - - - 0.81 - 2.096 0.478 - 356.6 1 2 0 0.0011 11 0 0 0 7.90E+06 4.76E+06 - - - 4.5731 0.9997 221125_WJC_METTL3_EV_vs_WT_F02.15767.15767.2 0.0352 16-Oct R.VLQALEGLK[136.11].M "sp|P39019|RS19_HUMAN,tr|A0A075B6E2|A0A075B6E2_HUMAN" 2 977.6001 1.09 15551 15767 2 977.599294 489.8073 40S ribosomal protein S19 OS=Homo sapiens OX=9606 GN=RPS19 PE=1 SV=2 5.97 3018.9 - 9.57E+06 - - - -0.8061 - 1.983 0.373 - 364.8 1 2 0 -0.0008 9 0 0 0 5.49E+09 5.02E+09 - - - 3.7763 0.9999 221125_WJC_METTL3_EV_vs_WT_F02.15768.15768.2 0.000867 20-Dec K.IAVAVLEETTR.E "sp|P0DJD0|RGPD1_HUMAN,sp|Q7Z3J3|RGPD4_HUMAN,sp|P49792|RBP2_HUMAN,sp|P0DJD1|RGPD2_HUMAN,sp|A6NKT7|RGPD3_HUMAN,tr|A0A286YES2|A0A286YES2_HUMAN,tr|F8VYC4|F8VYC4_HUMAN,tr|J3KNE0|J3KNE0_HUMAN,tr|A0A1W2PNU4|A0A1W2PNU4_HUMAN" 9 1200.6714 0.84 15552 15768 2 1200.671446 601.343 RANBP2-like and GRIP domain-containing protein 1 OS=Homo sapiens OX=9606 GN=RGPD1 PE=2 SV=1 4.53 3019 - 1.03E+06 - - - 0.0358 - 2.693 0.411 - 613 1 2 0 0 11 0 0 0 2.64E+07 3.15E+07 - - - 4.7566 0.8965 221125_WJC_METTL3_EV_vs_WT_F02.15769.15769.2 0.134 18-Aug R.YTAEEIEVLR[166.11].T sp|Q9Y6W3|CAN7_HUMAN 1 1231.6324 0.16 15553 15769 2 1231.62581 616.8235 Calpain-7 OS=Homo sapiens OX=9606 GN=CAPN7 PE=1 SV=1 4.25 3019.1 - 906562 - - - -5.3409 - 1.258 0.199 - 140.3 1 2 0 -0.0066 10 0 0 0 2.81E+06 1.78E+07 - - - 1.1494 0.9995 221125_WJC_METTL3_EV_vs_WT_F02.15772.15772.2 3.67E-07 18-Nov K.FMQASEDLLK.E "sp|P15531|NDKA_HUMAN,tr|Q32Q12|Q32Q12_HUMAN,tr|J3KPD9|J3KPD9_HUMAN,tr|E5RHP0|E5RHP0_HUMAN,tr|E7ERL0|E7ERL0_HUMAN" 5 1180.5798 1.47 15556 15772 2 1180.582851 591.2972 Nucleoside diphosphate kinase A OS=Homo sapiens OX=9606 GN=NME1 PE=1 SV=1 4.37 3019.4 - 724322 - - - 2.5759 - 1.834 0.537 - 355.8 1 2 0 0.003 10 0 0 0 4.80E+08 3.26E+08 - - - 4.6993 0.9984 221125_WJC_METTL3_EV_vs_WT_F02.15776.15776.2 0.000216 20-Nov R.EVQLEELEAAR.D "sp|P51570|GALK1_HUMAN,tr|K7EII7|K7EII7_HUMAN" 2 1285.6514 0.11 15560 15776 2 1285.646471 643.833 Galactokinase OS=Homo sapiens OX=9606 GN=GALK1 PE=1 SV=1 4.09 3019.9 - 254562 - - - -3.83 - 1.832 0.467 - 387.2 1 2 0 -0.0049 11 0 0 0 1.25E+07 1.10E+08 - - - 4.1265 0.9993 221125_WJC_METTL3_EV_vs_WT_F02.15779.15779.2 0.104 16-Oct R.VLQALEGLK.M "sp|P39019|RS19_HUMAN,tr|A0A075B6E2|A0A075B6E2_HUMAN" 2 969.5859 1.09 15561 15779 2 969.584903 485.8002 40S ribosomal protein S19 OS=Homo sapiens OX=9606 GN=RPS19 PE=1 SV=2 5.97 3020.3 - 2.48E+07 - - - -1.0097 - 1.911 0.258 - 362.3 1 2 0 -0.001 9 0 0 0 5.49E+09 5.02E+09 - - - 2.8199 0.9991 221125_WJC_METTL3_EV_vs_WT_F02.15780.15780.2 0.00302 16-Jul R.QPTPPFFGR.D sp|Q96PK6|RBM14_HUMAN 1 1045.5345 1.44 15562 15780 2 1045.534168 523.7745 RNA-binding protein 14 OS=Homo sapiens OX=9606 GN=RBM14 PE=1 SV=2 9.75 3020.4 - 1.25E+07 - - - -0.3319 - 1.364 0.336 - 211.8 1 2 0 -0.0003 9 0 0 0 7.06E+08 4.89E+08 - - - 2.4207 0.9744 221125_WJC_METTL3_EV_vs_WT_F02.15782.15782.2 0.00181 18-Nov K.FMQASEDLLK[136.11].E "sp|P15531|NDKA_HUMAN,tr|Q32Q12|Q32Q12_HUMAN,tr|J3KPD9|J3KPD9_HUMAN,tr|E5RHP0|E5RHP0_HUMAN,tr|E7ERL0|E7ERL0_HUMAN" 5 1188.594 1.47 15564 15782 2 1188.584223 595.3043 Nucleoside diphosphate kinase A OS=Homo sapiens OX=9606 GN=NME1 PE=1 SV=1 4.37 3020.5 - 2.06E+06 - - - -8.2341 - 1.944 0.446 - 333 1 2 0 -0.0098 10 0 0 0 4.80E+08 3.26E+08 - - - 4.1876 0.9972 221125_WJC_METTL3_EV_vs_WT_F02.15786.15786.2 5.09 14-Jul R.NELFLPGR[166.11].M "sp|Q13123|RED_HUMAN,tr|E7EQZ7|E7EQZ7_HUMAN" 2 954.5162 1.01 15567 15786 2 954.514852 478.2654 Protein Red OS=Homo sapiens OX=9606 GN=IK PE=1 SV=3 6 3020.9 - 3.61E+06 - - - -1.4499 - 1.612 0.184 - 237.5 1 2 0 -0.0014 8 0 0 0 1.33E+08 1.32E+08 - - - 1.8396 0.9876 221125_WJC_METTL3_EV_vs_WT_F02.15787.15787.2 0.889 14-Jul R.QAYNLENV.- sp|Q86U86|PB1_HUMAN 1 949.4505 - 15568 15787 2 949.449903 475.7325 Protein polybromo-1 OS=Homo sapiens OX=9606 GN=PBRM1 PE=1 SV=1 4 3021 - 3.22E+06 - - - -0.6404 - 1.153 0.141 - 157.6 1 2 0 -0.0006 8 0 0 0 - - - - - 0.5116 0.9991 221125_WJC_METTL3_EV_vs_WT_F02.15788.15788.2 0.0505 18-Aug K.LLSSLGIDTR.N "sp|Q6ULP2|AFTIN_HUMAN,tr|B8ZZI9|B8ZZI9_HUMAN" 2 1073.6081 1.13 15569 15788 2 1073.608414 537.8113 Aftiphilin OS=Homo sapiens OX=9606 GN=AFTPH PE=1 SV=3 5.84 3021 - 1.13E+07 - - - 0.3167 - 1.771 0.256 - 159.8 1 2 0 0.0003 10 0 0 0 4.30E+07 3.81E+07 - - - 2.5271 0.9998 221125_WJC_METTL3_EV_vs_WT_F02.15789.15789.2 0.00499 18-Nov K.LSELEAALQR[166.11].A sp|P05787|K2C8_HUMAN 1 1138.6222 1.77 15570 15789 2 1138.621761 570.3184 "Keratin, type II cytoskeletal 8 OS=Homo sapiens OX=9606 GN=KRT8 PE=1 SV=7" 4.53 3021.1 - 4.63E+06 - - - -0.3487 - 2.49 0.373 - 533.9 1 2 0 -0.0004 10 0 0 0 1.75E+08 9.86E+07 - - - 4.3423 0.9972 221125_WJC_METTL3_EV_vs_WT_F02.15792.15792.2 2.47 12-Oct K.IGIEIIK[136.11].R "sp|P10809|CH60_HUMAN,tr|A0A7I2V2X6|A0A7I2V2X6_HUMAN,tr|A0A7I2YQK6|A0A7I2YQK6_HUMAN,tr|A0A7I2V599|A0A7I2V599_HUMAN" 4 792.52 1.21 15573 15792 2 792.519602 397.2673 "60 kDa heat shock protein, mitochondrial OS=Homo sapiens OX=9606 GN=HSPD1 PE=1 SV=2" 6 3021.4 - 2.03E+06 - - - -0.5539 - 2.05 0.034 - 244.7 1 2 0 -0.0004 7 0 0 0 3.32E+08 2.75E+08 - - - 1.5665 0.9966 221125_WJC_METTL3_EV_vs_WT_F02.15793.15793.2 14.3 12-Oct K.IGIEIIK.R "sp|P10809|CH60_HUMAN,tr|A0A7I2V2X6|A0A7I2V2X6_HUMAN,tr|A0A7I2YQK6|A0A7I2YQK6_HUMAN,tr|A0A7I2V599|A0A7I2V599_HUMAN" 4 784.5058 1.21 15574 15793 2 784.505706 393.2602 "60 kDa heat shock protein, mitochondrial OS=Homo sapiens OX=9606 GN=HSPD1 PE=1 SV=2" 6 3021.5 - 1.81E+06 - - - -0.1721 - 1.97 0.027 - 248.9 1 2 0 -0.0001 7 0 0 0 3.32E+08 2.75E+08 - - - 1.3888 0.9993 221125_WJC_METTL3_EV_vs_WT_F02.15794.15794.2 4.71E-05 22-Nov R.IGAFGYMEC[160.03]SAK.T "sp|P61586|RHOA_HUMAN,tr|A0A7I2YQV1|A0A7I2YQV1_HUMAN" 2 1332.5842 1.52 15575 15794 2 1332.584533 667.2994 Transforming protein RhoA OS=Homo sapiens OX=9606 GN=RHOA PE=1 SV=1 5.99 3021.5 - 3.46E+06 - - - 0.2169 - 1.96 0.264 - 197.3 1 2 0 0.0003 12 0 0 0 3.87E+07 2.54E+07 - - - 2.7614 0.9995 221125_WJC_METTL3_EV_vs_WT_F02.15796.15796.2 0.00576 20-Sep R.LIVEPPLPQEK.A "sp|Q14687|GSE1_HUMAN,tr|C9JLW9|C9JLW9_HUMAN" 2 1261.7282 4.24 15577 15796 2 1261.728085 631.8714 Genetic suppressor element 1 OS=Homo sapiens OX=9606 GN=GSE1 PE=1 SV=3 4.53 3021.8 - 793387 - - - -0.0824 - 1.63 0.364 - 228.3 1 2 0 -0.0001 11 0 0 0 2.94E+07 6.92E+06 - - - 3.0512 0.985 221125_WJC_METTL3_EV_vs_WT_F02.15798.15798.2 0.277 14-Aug R.SDLGNLLK[136.11].A "sp|O15294|OGT1_HUMAN,tr|C9JZL3|C9JZL3_HUMAN" 2 866.4953 5.88 15579 15798 2 866.497062 434.2549 UDP-N-acetylglucosamine--peptide N-acetylglucosaminyltransferase 110 kDa subunit OS=Homo sapiens OX=9606 GN=OGT PE=1 SV=3 5.55 3022.1 - 488041 - - - 2.0531 - 1.412 0.116 - 160.9 1 2 0 0.0018 8 0 0 0 4.57E+07 7.77E+06 - - - 0.9377 1 221125_WJC_METTL3_EV_vs_WT_F02.15802.15802.2 2.35E-06 22-Dec R.LGSAMIGGFAGR[166.11].L "sp|Q9P2K5|MYEF2_HUMAN,tr|A0A0A0MR39|A0A0A0MR39_HUMAN,tr|A0A087WUT0|A0A087WUT0_HUMAN" 3 1145.5891 0.95 15581 15802 2 1145.585963 573.8018 Myelin expression factor 2 OS=Homo sapiens OX=9606 GN=MYEF2 PE=1 SV=3 9.75 3022.5 - 3.79E+06 - - - -2.7235 - 2.784 0.567 - 445.7 1 2 0 -0.0031 12 0 0 0 1.08E+08 1.14E+08 - - - 5.9219 0.9961 221125_WJC_METTL3_EV_vs_WT_F02.15806.15806.2 0.000277 24-Sep K.LLLSGTADGADLR[166.11].T "sp|O75179|ANR17_HUMAN,tr|H0YM23|H0YM23_HUMAN,tr|A0A1W2PQ15|A0A1W2PQ15_HUMAN" 3 1310.707 4.86 15585 15806 2 1310.699653 656.3608 Ankyrin repeat domain-containing protein 17 OS=Homo sapiens OX=9606 GN=ANKRD17 PE=1 SV=3 4.21 3022.9 - 1.79E+06 - - - -5.5672 - 1.988 0.524 - 205.2 1 2 0 -0.0073 13 0 0 0 1.31E+08 2.70E+07 - - - 4.6725 0.9886 221125_WJC_METTL3_EV_vs_WT_F02.15810.15810.2 0.109 14/24 R.QLLAGGIAGAVSR[166.11].T "sp|Q6NUK1|SCMC1_HUMAN,tr|A0A3B3IU96|A0A3B3IU96_HUMAN" 2 1221.7069 0.91 15589 15810 2 1221.700308 611.8607 Calcium-binding mitochondrial carrier protein SCaMC-1 OS=Homo sapiens OX=9606 GN=SLC25A24 PE=1 SV=2 9.75 3023.4 - 495863 - - - -5.3875 - 2.522 0.231 - 669.8 1 2 0 -0.0066 13 0 0 0 2.44E+07 2.69E+07 - - - 3.1193 0.9998 221125_WJC_METTL3_EV_vs_WT_F02.15812.15812.2 0.000696 13/18 R.VSALEVLPDR[166.11].V sp|Q9Y657|SPIN1_HUMAN 1 1107.6163 2.46 15590 15812 2 1107.615382 554.8154 Spindlin-1 OS=Homo sapiens OX=9606 GN=SPIN1 PE=1 SV=3 4.37 3023.6 - 1.90E+06 - - - -0.8685 - 2.495 0.382 - 712.6 1 2 0 -0.001 10 0 0 0 3.29E+08 1.34E+08 - - - 4.4142 1 221125_WJC_METTL3_EV_vs_WT_F02.15814.15814.3 2.79E-05 17/44 K.LLGHEVEDVIIK.C sp|Q92900|RENT1_HUMAN 1 1363.7711 0.71 15591 15814 3 1363.767848 455.5976 Regulator of nonsense transcripts 1 OS=Homo sapiens OX=9606 GN=UPF1 PE=1 SV=2 4.65 3023.8 - 1.51E+06 - - - -2.397 - 3.064 0.498 - 530.4 1 2 0 -0.0033 12 0 0 0 3.66E+07 5.17E+07 - - - 7.195 0.9997 221125_WJC_METTL3_EV_vs_WT_F02.15815.15815.2 0.0319 22-Nov K.LLGHEVEDVIIK.C sp|Q92900|RENT1_HUMAN 1 1363.7711 1.1 15592 15815 2 1363.769949 682.8928 Regulator of nonsense transcripts 1 OS=Homo sapiens OX=9606 GN=UPF1 PE=1 SV=2 4.65 3023.9 - 0 - - - -0.8564 - 2.358 0.354 - 391.5 1 2 0 -0.0012 12 0 0 0 1.18E+07 1.07E+07 - - - 3.9123 0.9947 221125_WJC_METTL3_EV_vs_WT_F02.15816.15816.2 0.000898 16-Sep K.EEVTELLAR[166.11].Y "sp|P19388|RPAB1_HUMAN,tr|A0A0A0MQR7|A0A0A0MQR7_HUMAN,tr|A0A087WVZ9|A0A087WVZ9_HUMAN,tr|A0A087WWX0|A0A087WWX0_HUMAN" 4 1068.5691 2.04 15593 15816 2 1068.563497 535.2918 "DNA-directed RNA polymerases I, II, and III subunit RPABC1 OS=Homo sapiens OX=9606 GN=POLR2E PE=1 SV=4" 4.25 3024 - 2.77E+06 - - - -5.2051 - 1.807 0.42 - 456.2 1 2 0 -0.0056 9 0 0 0 1.95E+08 9.56E+07 - - - 3.8531 0.9991 221125_WJC_METTL3_EV_vs_WT_F02.15817.15817.2 0.00808 12-Jun R.DYYINIR.K sp|O43143|DHX15_HUMAN 1 955.4763 1.19 15594 15817 2 955.475782 478.7454 Pre-mRNA-splicing factor ATP-dependent RNA helicase DHX15 OS=Homo sapiens OX=9606 GN=DHX15 PE=1 SV=2 5.83 3024 - 2.08E+06 - - - -0.5746 - 1.216 0.383 - 171.6 1 2 0 -0.0006 7 0 0 0 1.06E+08 8.95E+07 - - - 2.4893 0.9984 221125_WJC_METTL3_EV_vs_WT_F02.15819.15819.2 0.0047 16-Aug R.MSDGLFLQK.C "sp|P50213|IDH3A_HUMAN,tr|H0YL72|H0YL72_HUMAN" 2 1037.5216 0.03 15596 15819 2 1037.523778 519.7681 "Isocitrate dehydrogenase [NAD] subunit alpha, mitochondrial OS=Homo sapiens OX=9606 GN=IDH3A PE=1 SV=1" 5.59 3024.2 - 1.14E+06 - - - 2.131 - 1.555 0.336 - 136.9 1 2 0 0.0022 9 0 0 0 2.57E+07 7.89E+08 - - - 2.7992 0.9937 221125_WJC_METTL3_EV_vs_WT_F02.15822.15822.2 0.666 14-Jul K.IIIPEIQK[136.11].V sp|P55060|XPO2_HUMAN 1 960.6099 0.93 15597 15822 2 960.608525 481.3122 Exportin-2 OS=Homo sapiens OX=9606 GN=CSE1L PE=1 SV=3 6 3024.6 - 1.23E+06 - - - -1.4501 - 1.422 0.152 - 138.6 1 2 0 -0.0014 8 0 0 0 2.18E+08 2.35E+08 - - - 1.225 0.9996 221125_WJC_METTL3_EV_vs_WT_F02.15831.15831.2 0.00012 18-Dec K.TAEEVAALIR[166.11].S sp|Q6P2Q9|PRP8_HUMAN 1 1081.6007 1.26 15602 15831 2 1081.597745 541.8076 Pre-mRNA-processing-splicing factor 8 OS=Homo sapiens OX=9606 GN=PRPF8 PE=1 SV=2 4.53 3025.6 - 1.82E+06 - - - -2.7265 - 2.554 0.437 - 708.7 1 2 0 -0.0029 10 0 0 0 1.80E+08 1.43E+08 - - - 4.8851 0.9977 221125_WJC_METTL3_EV_vs_WT_F02.15832.15832.2 0.022 12-Jul R.NFDEILR[166.11].V sp|P30041|PRDX6_HUMAN 1 915.469 0.92 15603 15832 2 915.467041 458.7418 Peroxiredoxin-6 OS=Homo sapiens OX=9606 GN=PRDX6 PE=1 SV=3 4.37 3025.6 - 1.97E+06 - - - -2.0864 - 1.51 0.276 - 145.3 1 2 0 -0.0019 7 0 0 0 6.50E+07 7.09E+07 - - - 2.3847 0.9989 221125_WJC_METTL3_EV_vs_WT_F02.15836.15836.2 3.40E-05 18-Nov K.WTLLQEQGTK.T "sp|P48668|K2C6C_HUMAN,sp|P04259|K2C6B_HUMAN,sp|P13647|K2C5_HUMAN,sp|P02538|K2C6A_HUMAN,tr|F8W0C6|F8W0C6_HUMAN" 5 1202.6295 999 15606 15836 2 1202.626705 602.322 "Keratin, type II cytoskeletal 6C OS=Homo sapiens OX=9606 GN=KRT6C PE=1 SV=3" 6 3026.1 - 7.21E+06 - - - -2.3557 - 2.122 0.292 - 411.5 1 2 0 -0.0028 10 0 0 0 1.56E+08 0.00E+00 - - - 3.2969 0.975 221125_WJC_METTL3_EV_vs_WT_F02.15839.15839.2 0.0282 22-Oct K.ATGYPLAYVAAK[136.11].L "sp|P27708|PYR1_HUMAN,tr|F8VPD4|F8VPD4_HUMAN" 2 1231.6692 0.43 15608 15839 2 1231.675504 616.8419 CAD protein OS=Homo sapiens OX=9606 GN=CAD PE=1 SV=3 8.54 3026.4 - 1.04E+06 - - - 5.0988 - 1.481 0.289 - 228.7 1 2 0 0.0063 12 0 0 0 1.46E+07 3.37E+07 - - - 2.2069 0.9995 221125_WJC_METTL3_EV_vs_WT_F02.15840.15840.2 6.26E-05 18-Nov R.ISQDLALIAR[166.11].E "sp|Q96L14|C170L_HUMAN,sp|Q5SW79|CE170_HUMAN,tr|E5RGW7|E5RGW7_HUMAN,tr|H0Y2V6|H0Y2V6_HUMAN,tr|E7EMW0|E7EMW0_HUMAN,tr|H0Y4T4|H0Y4T4_HUMAN,tr|E7EWM2|E7EWM2_HUMAN,tr|E5RG47|E5RG47_HUMAN" 8 1108.648 1.35 15609 15840 2 1108.649233 555.3313 Cep170-like protein OS=Homo sapiens OX=9606 GN=CEP170P1 PE=5 SV=2 5.84 3026.6 - 1.66E+06 - - - 1.132 - 2.273 0.265 - 357.1 1 2 0 0.0013 10 0 0 0 4.31E+07 3.18E+07 - - - 3.2898 0.9999 221125_WJC_METTL3_EV_vs_WT_F02.15841.15841.2 0.000639 14/22 K.APILIATDVASR.G "sp|Q92841|DDX17_HUMAN,sp|P17844|DDX5_HUMAN,tr|A0A0U1RQJ0|A0A0U1RQJ0_HUMAN,tr|A0A7I2V5F5|A0A7I2V5F5_HUMAN,tr|A0A7I2V507|A0A7I2V507_HUMAN,tr|A0A5H1ZRQ2|A0A5H1ZRQ2_HUMAN,tr|J3KTA4|J3KTA4_HUMAN,tr|A0A0G2JLI4|A0A0G2JLI4_HUMAN,tr|A0A1X7SBZ2|A0A1X7SBZ2_HUMAN,tr|A0A7I2V2S0|A0A7I2V2S0_HUMAN" 10 1225.703 1.5 15610 15841 2 1225.703651 613.8588 Probable ATP-dependent RNA helicase DDX17 OS=Homo sapiens OX=9606 GN=DDX17 PE=1 SV=2 5.88 3026.7 - 1.65E+06 - - - 0.5009 - 2.93 0.415 - 954.6 1 2 0 0.0006 12 0 0 0 2.93E+09 1.95E+09 - - - 4.9345 0.9998 221125_WJC_METTL3_EV_vs_WT_F02.15842.15842.2 0.00117 13/22 K.APILIATDVASR[166.11].G "sp|Q92841|DDX17_HUMAN,sp|P17844|DDX5_HUMAN,tr|A0A0U1RQJ0|A0A0U1RQJ0_HUMAN,tr|A0A7I2V5F5|A0A7I2V5F5_HUMAN,tr|A0A7I2V507|A0A7I2V507_HUMAN,tr|A0A5H1ZRQ2|A0A5H1ZRQ2_HUMAN,tr|J3KTA4|J3KTA4_HUMAN,tr|A0A0G2JLI4|A0A0G2JLI4_HUMAN,tr|A0A1X7SBZ2|A0A1X7SBZ2_HUMAN,tr|A0A7I2V2S0|A0A7I2V2S0_HUMAN" 10 1235.7113 1.5 15611 15842 2 1235.709879 618.8629 Probable ATP-dependent RNA helicase DDX17 OS=Homo sapiens OX=9606 GN=DDX17 PE=1 SV=2 5.88 3026.8 - 1.29E+06 - - - -1.1556 - 2.865 0.377 - 783.8 1 2 0 -0.0014 12 0 0 0 2.93E+09 1.95E+09 - - - 4.5946 0.9971 221125_WJC_METTL3_EV_vs_WT_F02.15843.15843.2 0.0273 14-Jun R.EFALSNLK.A sp|Q9BUQ8|DDX23_HUMAN 1 920.4967 2.2 15612 15843 2 920.496057 461.2556 Probable ATP-dependent RNA helicase DDX23 OS=Homo sapiens OX=9606 GN=DDX23 PE=1 SV=3 6.1 3026.9 - 1.08E+06 - - - -0.7344 - 1.314 0.232 - 115.3 1 2 0 -0.0007 8 0 0 0 3.55E+07 1.61E+07 - - - 1.5779 0.9997 221125_WJC_METTL3_EV_vs_WT_F02.15844.15844.2 0.000776 22-Dec R.IGAFGYMEC[160.03]SAK[136.11].T "sp|P61586|RHOA_HUMAN,tr|A0A7I2YQV1|A0A7I2YQV1_HUMAN" 2 1340.5984 1.52 15613 15844 2 1340.59658 671.3065 Transforming protein RhoA OS=Homo sapiens OX=9606 GN=RHOA PE=1 SV=1 5.99 3027 - 805197 - - - -1.3904 - 1.646 0.495 - 261.4 1 2 0 -0.0019 12 0 0 0 3.87E+07 2.54E+07 - - - 4.0077 0.9995 221125_WJC_METTL3_EV_vs_WT_F02.15845.15845.2 0.00111 22-Oct K.LLEGTIVNVPEK.N sp|O76031|CLPX_HUMAN 1 1310.7446 0.83 15614 15845 2 1310.744446 656.3796 "ATP-dependent Clp protease ATP-binding subunit clpX-like, mitochondrial OS=Homo sapiens OX=9606 GN=CLPX PE=1 SV=2" 4.53 3027.1 - 660141 - - - -0.0931 - 1.887 0.304 - 241 1 2 0 -0.0001 12 0 0 0 1.61E+07 1.94E+07 - - - 2.9571 0.9999 221125_WJC_METTL3_EV_vs_WT_F02.15848.15848.2 3.42E-05 22-Oct R.LGSAMIGGFAGR.L "sp|Q9P2K5|MYEF2_HUMAN,tr|A0A0A0MR39|A0A0A0MR39_HUMAN,tr|A0A087WUT0|A0A087WUT0_HUMAN" 3 1135.5808 0.95 15615 15848 2 1135.579412 568.7977 Myelin expression factor 2 OS=Homo sapiens OX=9606 GN=MYEF2 PE=1 SV=3 9.75 3027.5 - 5.30E+06 - - - -1.2337 - 2.39 0.514 - 279.2 1 2 0 -0.0014 12 0 0 0 1.08E+08 1.14E+08 - - - 5.1295 0.9999 221125_WJC_METTL3_EV_vs_WT_F02.15849.15849.2 5.28E-05 20-Dec K.TGAAPIIDVVR[166.11].S "sp|P46776|RL27A_HUMAN,tr|E9PLX7|E9PLX7_HUMAN,tr|E9PLL6|E9PLL6_HUMAN,tr|E9PJD9|E9PJD9_HUMAN" 4 1120.648 0.99 15616 15849 2 1120.647112 561.3313 60S ribosomal protein L27a OS=Homo sapiens OX=9606 GN=RPL27A PE=1 SV=2 5.5 3027.6 - 2.53E+06 - - - -0.7728 - 2.293 0.516 - 585.9 1 2 0 -0.0009 11 0 0 0 6.68E+08 6.75E+08 - - - 5.0969 0.9998 221125_WJC_METTL3_EV_vs_WT_F02.15852.15852.2 5.98E-07 24-Nov K.LLLSGTADGADLR.T "sp|O75179|ANR17_HUMAN,tr|H0YM23|H0YM23_HUMAN,tr|A0A1W2PQ15|A0A1W2PQ15_HUMAN" 3 1300.6987 4.86 15619 15852 2 1300.701126 651.3566 Ankyrin repeat domain-containing protein 17 OS=Homo sapiens OX=9606 GN=ANKRD17 PE=1 SV=3 4.21 3027.9 - 1.49E+06 - - - 1.8805 - 2.449 0.545 - 370.5 1 2 0 0.0024 13 0 0 0 1.31E+08 2.70E+07 - - - 5.3644 0.9845 221125_WJC_METTL3_EV_vs_WT_F02.15853.15853.2 0.172 12-Jun K.ATIFNLK[136.11].C "sp|Q9BY44|EIF2A_HUMAN,tr|F8WAE5|F8WAE5_HUMAN,tr|H7C5R5|H7C5R5_HUMAN" 3 813.484 0.4 15620 15853 2 813.482097 407.7493 Eukaryotic translation initiation factor 2A OS=Homo sapiens OX=9606 GN=EIF2A PE=1 SV=3 8.8 3028 - 1.06E+06 - - - -2.327 - 1.251 0.17 - 145.2 1 2 0 -0.0019 7 0 0 0 5.79E+06 1.46E+07 - - - 1.0056 0.9986 221125_WJC_METTL3_EV_vs_WT_F02.15854.15854.2 0.00198 22-Nov K.LLEGTIVNVPEK[136.11].N sp|O76031|CLPX_HUMAN 1 1318.7588 1.3 15621 15854 2 1318.755278 660.3867 "ATP-dependent Clp protease ATP-binding subunit clpX-like, mitochondrial OS=Homo sapiens OX=9606 GN=CLPX PE=1 SV=2" 4.53 3028.1 - 936195 - - - -2.6464 - 1.659 0.388 - 281.4 1 2 0 -0.0035 12 0 0 0 3.49E+07 2.67E+07 - - - 3.2376 0.8335 221125_WJC_METTL3_EV_vs_WT_F02.15855.15855.2 0.595 12-Aug L.QALEGLK[136.11].M "sp|P39019|RS19_HUMAN,tr|A0A075B6E2|A0A075B6E2_HUMAN" 2 765.4476 0.06 15622 15855 2 765.446937 383.7311 40S ribosomal protein S19 OS=Homo sapiens OX=9606 GN=RPS19 PE=1 SV=2 6 3028.2 - 824462 - - - -0.8714 - 1.469 0.168 - 198.2 1 1 0 -0.0007 7 0 0 0 6.14E+05 9.90E+06 - - - 1.5002 0.9995 221125_WJC_METTL3_EV_vs_WT_F02.15857.15857.2 0.0123 16-Aug R.GLGLSIVGK.R "sp|Q8NI35|INADL_HUMAN,sp|O75970|MPDZ_HUMAN,tr|A0A2R8Y549|A0A2R8Y549_HUMAN,tr|A0A2R8Y5I3|A0A2R8Y5I3_HUMAN,tr|B7ZB24|B7ZB24_HUMAN,tr|A0A0U1RQR3|A0A0U1RQR3_HUMAN,tr|A0A0U1RQT2|A0A0U1RQT2_HUMAN,tr|H0YGQ3|H0YGQ3_HUMAN,tr|F5H1U9|F5H1U9_HUMAN,tr|B4DE90|B4DE90_HUMAN,tr|A0A075B6R8|A0A075B6R8_HUMAN" 11 842.5226 1.64 15624 15857 2 842.521826 422.2686 InaD-like protein OS=Homo sapiens OX=9606 GN=PATJ PE=1 SV=3 8.75 3028.5 - 569716 - - - -0.8629 - 1.594 0.373 - 152.9 1 2 0 -0.0007 9 0 0 0 9.79E+06 5.98E+06 - - - 3.1446 0.9996 221125_WJC_METTL3_EV_vs_WT_F02.15860.15860.2 0.000247 16-Aug R.QPTPPFFGR[166.11].D sp|Q96PK6|RBM14_HUMAN 1 1055.5428 1.44 15625 15860 2 1055.541999 528.7787 RNA-binding protein 14 OS=Homo sapiens OX=9606 GN=RBM14 PE=1 SV=2 9.75 3028.9 - 1.73E+07 - - - -0.7446 - 1.517 0.416 - 299.2 1 2 0 -0.0008 9 0 0 0 7.06E+08 4.89E+08 - - - 3.319 0.9986 221125_WJC_METTL3_EV_vs_WT_F02.15861.15861.2 0.00421 14-Jul K.QFFVAVER.E "sp|P38919|IF4A3_HUMAN,tr|I3L3H2|I3L3H2_HUMAN" 2 994.5236 1.34 15626 15861 2 994.521351 498.2691 Eukaryotic initiation factor 4A-III OS=Homo sapiens OX=9606 GN=EIF4A3 PE=1 SV=4 6 3028.9 - 3.94E+06 - - - -2.2775 - 1.555 0.354 - 227 1 2 0 -0.0023 8 0 0 0 1.66E+08 1.24E+08 - - - 2.9864 0.9732 221125_WJC_METTL3_EV_vs_WT_F02.15862.15862.2 0.409 14-Jul R.TPTFPQFR[166.11].T "sp|Q9H1Z4|WDR13_HUMAN,tr|A0A087WWV5|A0A087WWV5_HUMAN" 2 1002.5162 1.27 15627 15862 2 1002.513049 502.2654 WD repeat-containing protein 13 OS=Homo sapiens OX=9606 GN=WDR13 PE=1 SV=2 9.41 3029 - 3.15E+06 - - - -3.179 - 1.353 0.149 - 188.4 1 2 0 -0.0032 8 0 0 0 1.96E+08 1.54E+08 - - - 1.0523 0.9949 221125_WJC_METTL3_EV_vs_WT_F02.15863.15863.2 0.000142 22-Dec K.VLYDAEISQIHQ.S sp|P35908|K22E_HUMAN 1 1414.7092 - 15628 15863 2 1414.709756 708.3619 "Keratin, type II cytoskeletal 2 epidermal OS=Homo sapiens OX=9606 GN=KRT2 PE=1 SV=2" 4.35 3029.1 - 2.02E+06 - - - 0.3612 - 2.657 0.556 - 415.4 1 1 0 0.0005 12 0 0 0 - - - - - 5.7186 0.9971 221125_WJC_METTL3_EV_vs_WT_F02.15864.15864.2 0.242 14-Aug R.EFALSNLK[136.11].A sp|Q9BUQ8|DDX23_HUMAN 1 928.5109 2.23 15629 15864 2 928.51125 465.2627 Probable ATP-dependent RNA helicase DDX23 OS=Homo sapiens OX=9606 GN=DDX23 PE=1 SV=3 6.1 3029.3 - 834658 - - - 0.3414 - 1.528 0.164 - 191.8 1 2 0 0.0003 8 0 0 0 3.61E+07 1.62E+07 - - - 1.5308 0.9988 221125_WJC_METTL3_EV_vs_WT_F02.15865.15865.2 0.0235 24-Jul R.IITYNEAMDSPDQ.- sp|Q7Z417|NUFP2_HUMAN 1 1495.6501 - 15630 15865 2 1495.648779 748.8323 Nuclear fragile X mental retardation-interacting protein 2 OS=Homo sapiens OX=9606 GN=NUFIP2 PE=1 SV=1 3.49 3029.4 - 681447 - - - -0.8665 - 1.374 0.338 - 115.1 1 2 0 -0.0013 13 0 0 0 - - - - - 2.3525 0.9992 221125_WJC_METTL3_EV_vs_WT_F02.15866.15866.2 0.00157 16-Sep R.ISVPIDLQK[136.11].V "sp|P49642|PRI1_HUMAN,tr|H0YIP2|H0YIP2_HUMAN,tr|A0A5F9ZHB6|A0A5F9ZHB6_HUMAN,tr|A0A3B3ITS8|A0A3B3ITS8_HUMAN" 4 1019.6106 0.5 15631 15866 2 1019.613601 510.8126 DNA primase small subunit OS=Homo sapiens OX=9606 GN=PRIM1 PE=1 SV=1 5.84 3029.5 - 625447 - - - 2.8972 - 2.096 0.406 - 191.8 1 2 0 0.003 9 0 0 0 9.91E+06 1.98E+07 - - - 4.1797 0.9627 221125_WJC_METTL3_EV_vs_WT_F02.15868.15868.2 2.57 12-May K.ATIFNLK.C "sp|Q9BY44|EIF2A_HUMAN,tr|F8WAE5|F8WAE5_HUMAN,tr|H7C5R5|H7C5R5_HUMAN" 3 805.4698 0.39 15633 15868 2 805.46892 403.7422 Eukaryotic translation initiation factor 2A OS=Homo sapiens OX=9606 GN=EIF2A PE=1 SV=3 8.8 3029.8 - 321399 - - - -1.0801 - 1.139 0.077 - 78.8 2 2 0 -0.0009 7 0 0 0 5.68E+06 1.46E+07 - - - -0.1126 0.9986 221125_WJC_METTL3_EV_vs_WT_F02.15872.15872.2 0.362 12-Aug R.NFDEILR.V sp|P30041|PRDX6_HUMAN 1 905.4607 0.92 15635 15872 2 905.46021 453.7376 Peroxiredoxin-6 OS=Homo sapiens OX=9606 GN=PRDX6 PE=1 SV=3 4.37 3030.2 - 4.17E+06 - - - -0.5202 - 1.571 0.225 - 364.7 1 2 0 -0.0005 7 0 0 0 6.53E+07 7.09E+07 - - - 2.134 1 221125_WJC_METTL3_EV_vs_WT_F02.15874.15874.2 0.000423 18-Nov R.AAEVWMDEYK.E "sp|Q8N4A0|GALT4_HUMAN,sp|Q10471|GALT2_HUMAN,tr|F8VUJ3|F8VUJ3_HUMAN" 3 1240.5434 1.4 15637 15874 2 1240.542615 621.279 Polypeptide N-acetylgalactosaminyltransferase 4 OS=Homo sapiens OX=9606 GN=GALNT4 PE=1 SV=2 4.14 3030.3 - 3.65E+06 - - - -0.6529 - 2.337 0.587 - 562.6 1 2 0 -0.0008 10 0 0 0 1.11E+08 7.98E+07 - - - 5.7458 0.9997 221125_WJC_METTL3_EV_vs_WT_F02.15875.15875.2 0.000846 20-Nov M.VPPVQVSPLIK.L sp|P56385|ATP5I_HUMAN 1 1175.7278 1.74 15638 15875 2 1175.72674 588.8712 "ATP synthase subunit e, mitochondrial OS=Homo sapiens OX=9606 GN=ATP5ME PE=1 SV=2" 8.72 3030.3 - 3.53E+06 - - - -0.8973 - 1.789 0.447 - 324 1 2 0 -0.0011 11 0 0 0 2.14E+08 1.23E+08 - - - 3.9157 0.9997 221125_WJC_METTL3_EV_vs_WT_F02.15876.15876.2 0.000707 14-Aug R.TYLNLMGK.S sp|Q13835|PKP1_HUMAN 1 938.4895 20.94 15639 15876 2 938.489191 470.252 Plakophilin-1 OS=Homo sapiens OX=9606 GN=PKP1 PE=1 SV=2 8.26 3030.4 - 2.08E+06 - - - -0.3708 - 1.472 0.467 - 216.3 1 2 0 -0.0003 8 0 0 0 2.61E+07 1.25E+06 - - - 3.6562 0.9998 221125_WJC_METTL3_EV_vs_WT_F02.15877.15877.2 0.00045 16-Oct K.NFITAEELR.R "sp|O43707|ACTN4_HUMAN,tr|F5GXS2|F5GXS2_HUMAN,tr|H7C144|H7C144_HUMAN" 3 1091.5611 1.53 15640 15877 2 1091.561624 546.7878 Alpha-actinin-4 OS=Homo sapiens OX=9606 GN=ACTN4 PE=1 SV=2 4.53 3030.5 - 1.71E+06 - - - 0.4581 - 2.077 0.413 - 482 1 2 0 0.0005 9 0 0 0 2.21E+07 1.45E+07 - - - 4.2059 0.9998 221125_WJC_METTL3_EV_vs_WT_F02.15878.15878.2 3.62E-05 20-Oct K.NMVPQQALVIR.N "sp|P05023|AT1A1_HUMAN,sp|P13637|AT1A3_HUMAN,sp|Q13733|AT1A4_HUMAN,sp|P50993|AT1A2_HUMAN,tr|A0A0A0MT26|A0A0A0MT26_HUMAN,tr|M0QXF2|M0QXF2_HUMAN,tr|Q5TC01|Q5TC01_HUMAN,tr|A0A2R8YEY8|A0A2R8YEY8_HUMAN,tr|E9PRA5|E9PRA5_HUMAN,tr|B1AKY9|B1AKY9_HUMAN,tr|M0R116|M0R116_HUMAN" 11 1267.7071 0.63 15641 15878 2 1267.70608 634.8608 Sodium\potassium-transporting ATPase subunit alpha-1 OS=Homo sapiens OX=9606 GN=ATP1A1 PE=1 SV=1 9.75 3030.6 - 1.58E+06 - - - -0.7865 - 1.823 0.461 - 297.5 1 2 0 -0.001 11 0 0 0 4.53E+07 7.21E+07 - - - 4.0701 0.9999 221125_WJC_METTL3_EV_vs_WT_F02.15879.15879.3 0.00756 15/40 R.IVALNAHTFLR[166.11].N "sp|P22087|FBRL_HUMAN,sp|A6NHQ2|FBLL1_HUMAN,tr|M0R299|M0R299_HUMAN,tr|M0R0P1|M0R0P1_HUMAN,tr|M0QXL5|M0QXL5_HUMAN,tr|M0R2Q4|M0R2Q4_HUMAN" 6 1263.7327 0.81 15642 15879 3 1263.732125 422.2515 rRNA 2'-O-methyltransferase fibrillarin OS=Homo sapiens OX=9606 GN=FBL PE=1 SV=2 9.76 3030.7 - 985200 - - - -0.4637 - 2.795 0.354 - 332.8 1 2 0 -0.0006 11 0 0 0 1.08E+08 1.33E+08 - - - 5.4065 0.9993 221125_WJC_METTL3_EV_vs_WT_F02.15880.15880.3 7.43E-05 13/44 K.APILIATDVASR[166.11].G "sp|Q92841|DDX17_HUMAN,sp|P17844|DDX5_HUMAN,tr|A0A0U1RQJ0|A0A0U1RQJ0_HUMAN,tr|A0A7I2V5F5|A0A7I2V5F5_HUMAN,tr|A0A7I2V507|A0A7I2V507_HUMAN,tr|A0A5H1ZRQ2|A0A5H1ZRQ2_HUMAN,tr|J3KTA4|J3KTA4_HUMAN,tr|A0A0G2JLI4|A0A0G2JLI4_HUMAN,tr|A0A1X7SBZ2|A0A1X7SBZ2_HUMAN,tr|A0A7I2V2S0|A0A7I2V2S0_HUMAN" 10 1235.7113 1.56 15643 15880 3 1235.717258 412.911 Probable ATP-dependent RNA helicase DDX17 OS=Homo sapiens OX=9606 GN=DDX17 PE=1 SV=2 5.88 3030.8 - 894652 - - - 4.8158 - 2.42 0.438 - 267.2 1 2 0 0.006 12 0 0 0 6.70E+07 4.28E+07 - - - 5.8713 0.9971 221125_WJC_METTL3_EV_vs_WT_F02.15882.15882.2 0.167 16-Sep R.ISVPIDLQK.V "sp|P49642|PRI1_HUMAN,tr|H0YIP2|H0YIP2_HUMAN,tr|A0A5F9ZHB6|A0A5F9ZHB6_HUMAN,tr|A0A3B3ITS8|A0A3B3ITS8_HUMAN" 4 1011.5964 0.48 15645 15882 2 1011.595037 506.8055 DNA primase small subunit OS=Homo sapiens OX=9606 GN=PRIM1 PE=1 SV=1 5.84 3031 - 635725 - - - -1.3938 - 1.339 0.26 - 167.4 1 2 0 -0.0014 9 0 0 0 9.91E+06 2.06E+07 - - - 1.8055 0.9954 221125_WJC_METTL3_EV_vs_WT_F02.15883.15883.2 0.322 16-Jul R.GLGLSIVGK[136.11].R "sp|Q8NI35|INADL_HUMAN,sp|O75970|MPDZ_HUMAN,tr|A0A2R8Y549|A0A2R8Y549_HUMAN,tr|A0A2R8Y5I3|A0A2R8Y5I3_HUMAN,tr|B7ZB24|B7ZB24_HUMAN,tr|A0A0U1RQR3|A0A0U1RQR3_HUMAN,tr|A0A0U1RQT2|A0A0U1RQT2_HUMAN,tr|H0YGQ3|H0YGQ3_HUMAN,tr|F5H1U9|F5H1U9_HUMAN,tr|B4DE90|B4DE90_HUMAN,tr|A0A075B6R8|A0A075B6R8_HUMAN" 11 850.5368 1.64 15646 15883 2 850.534884 426.2757 InaD-like protein OS=Homo sapiens OX=9606 GN=PATJ PE=1 SV=3 8.75 3031.1 - 389722 - - - -2.1974 - 1.473 0.228 - 114.5 1 2 0 -0.0019 9 0 0 0 9.79E+06 5.98E+06 - - - 1.8449 0.9998 221125_WJC_METTL3_EV_vs_WT_F02.15887.15887.2 0.000443 16-Oct K.TLAIELAPR[166.11].N "sp|P0CG22|DR4L1_HUMAN,sp|Q6PKH6|DR4L2_HUMAN,sp|Q9BTZ2|DHRS4_HUMAN,tr|A0A087WSZ6|A0A087WSZ6_HUMAN,tr|F6TD35|F6TD35_HUMAN,tr|F6VUV4|F6VUV4_HUMAN,tr|A0A087WXI8|A0A087WXI8_HUMAN,tr|H0YKN3|H0YKN3_HUMAN" 8 992.5894 1.5 15648 15887 2 992.588472 497.302 Putative dehydrogenase\reductase SDR family member 4-like 1 OS=Homo sapiens OX=9606 GN=DHRS4L1 PE=5 SV=1 5.66 3031.7 - 5.60E+06 - - - -0.9359 - 1.975 0.446 - 394.7 1 2 0 -0.0009 9 0 0 0 7.57E+08 5.04E+08 - - - 4.3038 0.9997 221125_WJC_METTL3_EV_vs_WT_F02.15888.15888.2 0.00479 18-Sep K.ISYSGQFLVK[136.11].S sp|Q9NZI8|IF2B1_HUMAN 1 1148.6321 1.47 15649 15888 2 1148.632179 575.3233 Insulin-like growth factor 2 mRNA-binding protein 1 OS=Homo sapiens OX=9606 GN=IGF2BP1 PE=1 SV=2 8.59 3031.7 - 2.80E+06 - - - 0.0601 - 1.699 0.404 - 157.8 1 2 0 0.0001 10 0 0 0 5.96E+08 4.06E+08 - - - 3.5044 0.9995 221125_WJC_METTL3_EV_vs_WT_F02.15889.15889.2 0.000237 22-Sep R.YLGDLSGGQVLK[136.11].K "sp|P09601|HMOX1_HUMAN,tr|B1AHA8|B1AHA8_HUMAN,tr|A0A7I2V3I1|A0A7I2V3I1_HUMAN" 3 1256.6856 1.6 15650 15889 2 1256.684399 629.3501 Heme oxygenase 1 OS=Homo sapiens OX=9606 GN=HMOX1 PE=1 SV=1 5.83 3031.8 - 1.90E+06 - - - -0.9581 - 1.529 0.423 - 126.6 1 2 0 -0.0012 12 0 0 0 6.66E+07 4.17E+07 - - - 3.2821 0.9999 221125_WJC_METTL3_EV_vs_WT_F02.15890.15890.3 4.80E-06 Nov-44 K.APILIATDVASR.G "sp|Q92841|DDX17_HUMAN,sp|P17844|DDX5_HUMAN,tr|A0A0U1RQJ0|A0A0U1RQJ0_HUMAN,tr|A0A7I2V5F5|A0A7I2V5F5_HUMAN,tr|A0A7I2V507|A0A7I2V507_HUMAN,tr|A0A5H1ZRQ2|A0A5H1ZRQ2_HUMAN,tr|J3KTA4|J3KTA4_HUMAN,tr|A0A0G2JLI4|A0A0G2JLI4_HUMAN,tr|A0A1X7SBZ2|A0A1X7SBZ2_HUMAN,tr|A0A7I2V2S0|A0A7I2V2S0_HUMAN" 10 1225.703 1.57 15651 15890 3 1225.70217 409.575 Probable ATP-dependent RNA helicase DDX17 OS=Homo sapiens OX=9606 GN=DDX17 PE=1 SV=2 5.88 3031.9 - 1.77E+06 - - - -0.7073 - 2.398 0.423 - 229 1 2 0 -0.0009 12 0 0 0 6.70E+07 4.27E+07 - - - 5.6801 1 221125_WJC_METTL3_EV_vs_WT_F02.15891.15891.3 0.000432 16/40 R.IVALNAHTFLR.N "sp|P22087|FBRL_HUMAN,sp|A6NHQ2|FBLL1_HUMAN,tr|M0R299|M0R299_HUMAN,tr|M0R0P1|M0R0P1_HUMAN,tr|M0QXL5|M0QXL5_HUMAN,tr|M0R2Q4|M0R2Q4_HUMAN" 6 1253.7244 0.77 15652 15891 3 1253.723296 418.9154 rRNA 2'-O-methyltransferase fibrillarin OS=Homo sapiens OX=9606 GN=FBL PE=1 SV=2 9.76 3031.9 - 1.54E+06 - - - -0.9133 - 3.252 0.403 - 544.2 1 2 0 -0.0011 11 0 0 0 1.10E+08 1.43E+08 - - - 6.3828 0.9996 221125_WJC_METTL3_EV_vs_WT_F02.15892.15892.2 0.052 24-Oct R.LLALEEAAAAPAR.D "sp|Q5TA31|RN187_HUMAN,tr|A0A1X7SBW3|A0A1X7SBW3_HUMAN" 2 1294.7245 2.43 15653 15892 2 1294.723348 648.3695 E3 ubiquitin-protein ligase RNF187 OS=Homo sapiens OX=9606 GN=RNF187 PE=1 SV=2 4.53 3032.1 - 464634 - - - -0.8905 - 2.154 0.311 - 213.5 1 2 0 -0.0012 13 0 0 0 8.49E+07 3.50E+07 - - - 3.3071 0.9993 221125_WJC_METTL3_EV_vs_WT_F02.15895.15895.2 0.000166 24-Nov R.ILPVAASYSAVTR.F "sp|Q9BSJ2|GCP2_HUMAN,tr|A0A804HJH7|A0A804HJH7_HUMAN,tr|F2Z2B9|F2Z2B9_HUMAN,tr|A0A804HK74|A0A804HK74_HUMAN,tr|A0A804HL95|A0A804HL95_HUMAN,tr|A0A804HJ08|A0A804HJ08_HUMAN,tr|A0A804HJQ4|A0A804HJQ4_HUMAN,tr|A0A804HJS9|A0A804HJS9_HUMAN,tr|A0A804HI27|A0A804HI27_HUMAN" 9 1346.7558 0.49 15656 15895 2 1346.752911 674.3852 Gamma-tubulin complex component 2 OS=Homo sapiens OX=9606 GN=TUBGCP2 PE=1 SV=2 8.75 3032.5 - 374830 - - - -2.1459 - 1.8 0.413 - 347.3 1 2 0 -0.0029 13 0 0 0 1.92E+07 3.94E+07 - - - 3.5991 0.9997 221125_WJC_METTL3_EV_vs_WT_F02.15899.15899.2 0.00265 16-Sep K.TLAIELAPR.N "sp|P0CG22|DR4L1_HUMAN,sp|Q6PKH6|DR4L2_HUMAN,sp|Q9BTZ2|DHRS4_HUMAN,tr|A0A087WSZ6|A0A087WSZ6_HUMAN,tr|F6TD35|F6TD35_HUMAN,tr|F6VUV4|F6VUV4_HUMAN,tr|A0A087WXI8|A0A087WXI8_HUMAN,tr|H0YKN3|H0YKN3_HUMAN" 8 982.5811 1.48 15658 15899 2 982.580347 492.2978 Putative dehydrogenase\reductase SDR family member 4-like 1 OS=Homo sapiens OX=9606 GN=DHRS4L1 PE=5 SV=1 5.66 3033 - 1.57E+07 - - - -0.7979 - 1.772 0.405 - 325.5 1 2 0 -0.0008 9 0 0 0 7.45E+08 5.04E+08 - - - 3.6872 0.999 221125_WJC_METTL3_EV_vs_WT_F02.15900.15900.2 0.497 14-Aug K.IIIPEIQK.V sp|P55060|XPO2_HUMAN 1 952.5957 0.93 15659 15900 2 952.595693 477.3051 Exportin-2 OS=Homo sapiens OX=9606 GN=CSE1L PE=1 SV=3 6 3033 - 5.59E+06 - - - -0.0262 - 1.67 0.239 - 213 1 2 0 0 8 0 0 0 2.18E+08 2.35E+08 - - - 2.3529 0.9993 221125_WJC_METTL3_EV_vs_WT_F02.15901.15901.2 0.0588 16-Nov R.AIAFLQQPR[166.11].S sp|P22102|PUR2_HUMAN 1 1052.6006 0.83 15660 15901 2 1052.600189 527.3076 Trifunctional purine biosynthetic protein adenosine-3 OS=Homo sapiens OX=9606 GN=GART PE=1 SV=1 9.79 3033.1 - 5.53E+06 - - - -0.4228 - 1.911 0.244 - 616.1 1 2 0 -0.0004 9 0 0 0 6.43E+07 7.75E+07 - - - 2.7167 0.9989 221125_WJC_METTL3_EV_vs_WT_F02.15902.15902.2 0.0116 22-Aug R.YLGDLSGGQVLK.K "sp|P09601|HMOX1_HUMAN,tr|B1AHA8|B1AHA8_HUMAN,tr|A0A7I2V3I1|A0A7I2V3I1_HUMAN" 3 1248.6714 1.66 15661 15902 2 1248.671214 625.343 Heme oxygenase 1 OS=Homo sapiens OX=9606 GN=HMOX1 PE=1 SV=1 5.83 3033.1 - 4.16E+06 - - - -0.1514 - 1.324 0.344 - 100.7 1 2 0 -0.0002 12 0 0 0 6.88E+07 4.15E+07 - - - 2.3202 0.9974 221125_WJC_METTL3_EV_vs_WT_F02.15903.15903.2 0.14 14-Aug K.ESILDLSK.Y "sp|Q9UK45|LSM7_HUMAN,tr|K7ENY5|K7ENY5_HUMAN,tr|K7EML7|K7EML7_HUMAN" 3 903.4913 2.22 15662 15903 2 903.490036 452.7529 U6 snRNA-associated Sm-like protein LSm7 OS=Homo sapiens OX=9606 GN=LSM7 PE=1 SV=1 4.37 3033.2 - 3.48E+06 - - - -1.4134 - 1.468 0.229 - 192.5 1 2 0 -0.0013 8 0 0 0 3.33E+08 1.50E+08 - - - 1.8898 0.9998 221125_WJC_METTL3_EV_vs_WT_F02.15904.15904.2 0.00132 20-Nov M.VPPVQVSPLIK[136.11].L sp|P56385|ATP5I_HUMAN 1 1183.742 1.74 15663 15904 2 1183.741403 592.8783 "ATP synthase subunit e, mitochondrial OS=Homo sapiens OX=9606 GN=ATP5ME PE=1 SV=2" 8.72 3033.2 - 3.14E+06 - - - -0.5001 - 2.046 0.437 - 389.5 1 2 0 -0.0006 11 0 0 0 2.14E+08 1.23E+08 - - - 4.2051 0.9994 221125_WJC_METTL3_EV_vs_WT_F02.15905.15905.2 0.0809 14-Oct K.QLLEELER.Q sp|Q9NWB6|ARGL1_HUMAN 1 1028.5502 0.34 15664 15905 2 1028.550198 515.2824 Arginine and glutamate-rich protein 1 OS=Homo sapiens OX=9606 GN=ARGLU1 PE=1 SV=1 4.25 3033.3 - 2.03E+06 - - - -0.0263 - 1.662 0.311 - 408.5 1 2 0 0 8 0 0 0 2.19E+07 6.51E+07 - - - 2.8702 0.9702 221125_WJC_METTL3_EV_vs_WT_F02.15906.15906.2 0.0122 24-Jul K.IMQSSSEVGYDAM.A "sp|P10809|CH60_HUMAN,tr|A0A7I2V2X6|A0A7I2V2X6_HUMAN,tr|A0A7I2YQK6|A0A7I2YQK6_HUMAN,tr|A0A7I2V599|A0A7I2V599_HUMAN" 4 1416.5901 - 15665 15906 2 1416.590339 709.3023 "60 kDa heat shock protein, mitochondrial OS=Homo sapiens OX=9606 GN=HSPD1 PE=1 SV=2" 3.67 3033.4 - 1.77E+06 - - - 0.1567 - 1.584 0.378 - 94.6 1 1 0 0.0002 13 0 0 0 - - - - - 3.0133 0.9472 221125_WJC_METTL3_EV_vs_WT_F02.15908.15908.2 0.0158 22-Oct R.GLTLAPGLSPAR[166.11].P sp|Q8IU81|I2BP1_HUMAN 1 1161.6745 1.73 15667 15908 2 1161.676238 581.8445 Interferon regulatory factor 2-binding protein 1 OS=Homo sapiens OX=9606 GN=IRF2BP1 PE=1 SV=1 9.75 3033.5 - 1.04E+06 - - - 1.472 - 1.878 0.302 - 200.8 1 1 0 0.0017 12 0 0 0 2.74E+07 1.58E+07 - - - 2.9292 0.9987 221125_WJC_METTL3_EV_vs_WT_F02.15909.15909.2 0.38 14-Aug K.TTVLDVMR.R "sp|Q9NRH3|TBG2_HUMAN,sp|P23258|TBG1_HUMAN,tr|A0A7P0T9G6|A0A7P0T9G6_HUMAN" 3 933.4954 0.74 15668 15909 2 933.494405 467.755 Tubulin gamma-2 chain OS=Homo sapiens OX=9606 GN=TUBG2 PE=2 SV=1 5.5 3033.6 - 657902 - - - -1.0145 - 1.506 0.277 - 134.1 1 2 0 -0.0009 8 0 0 0 1.21E+07 1.63E+07 - - - 2.3215 0.957 221125_WJC_METTL3_EV_vs_WT_F02.15914.15914.2 0.00152 24-Oct K.SINPDEAVAYGAA.V "sp|P54652|HSP72_HUMAN,sp|P0DMV8|HS71A_HUMAN,sp|P34931|HS71L_HUMAN,sp|P11142|HSP7C_HUMAN,sp|P0DMV9|HS71B_HUMAN,sp|P17066|HSP76_HUMAN,tr|E9PNE6|E9PNE6_HUMAN,tr|A8K7Q2|A8K7Q2_HUMAN,tr|E9PKE3|E9PKE3_HUMAN,tr|Q53FA3|Q53FA3_HUMAN,tr|V9GZ37|V9GZ37_HUMAN,tr|A0A0G2JIW1|A0A0G2JIW1_HUMAN" 12 1276.5935 - 15671 15914 2 1276.591269 639.304 Heat shock-related 70 kDa protein 2 OS=Homo sapiens OX=9606 GN=HSPA2 PE=1 SV=1 3.67 3034.2 - 3.55E+06 - - - -1.7837 - 1.635 0.399 - 174.7 1 1 0 -0.0023 13 0 0 0 - - - - - 3.2491 0.9933 221125_WJC_METTL3_EV_vs_WT_F02.15915.15915.2 0.765 14-Jun K.ESILDLSK[136.11].Y "sp|Q9UK45|LSM7_HUMAN,tr|K7ENY5|K7ENY5_HUMAN,tr|K7EML7|K7EML7_HUMAN" 3 911.5055 2.32 15672 15915 2 911.50507 456.76 U6 snRNA-associated Sm-like protein LSm7 OS=Homo sapiens OX=9606 GN=LSM7 PE=1 SV=1 4.37 3034.2 - 2.66E+06 - - - -0.486 - 1.287 0.169 - 117.5 2 2 0 -0.0004 8 0 0 0 3.33E+08 1.43E+08 - - - 0.9156 0.9321 221125_WJC_METTL3_EV_vs_WT_F02.15916.15916.2 0.0023 24-Dec R.ILPVAASYSAVTR[166.11].F "sp|Q9BSJ2|GCP2_HUMAN,tr|A0A804HJH7|A0A804HJH7_HUMAN,tr|F2Z2B9|F2Z2B9_HUMAN,tr|A0A804HK74|A0A804HK74_HUMAN,tr|A0A804HL95|A0A804HL95_HUMAN,tr|A0A804HJ08|A0A804HJ08_HUMAN,tr|A0A804HJQ4|A0A804HJQ4_HUMAN,tr|A0A804HJS9|A0A804HJS9_HUMAN,tr|A0A804HI27|A0A804HI27_HUMAN" 9 1356.7641 0.48 15673 15916 2 1357.762843 679.3893 Gamma-tubulin complex component 2 OS=Homo sapiens OX=9606 GN=TUBGCP2 PE=1 SV=2 8.75 3034.4 - 1.24E+06 - - - 736.1427 - 2.258 0.373 - 504.4 1 2 0 0.9988 13 0 0 0 1.92E+07 3.98E+07 - - - 3.5727 0.9969 221125_WJC_METTL3_EV_vs_WT_F02.15923.15923.2 0.000232 18-Oct K.C[160.03]VLVWEGTAK.D sp|O43395|PRPF3_HUMAN 1 1161.5852 1.97 15677 15923 2 1161.579482 581.7999 U4\U6 small nuclear ribonucleoprotein Prp3 OS=Homo sapiens OX=9606 GN=PRPF3 PE=1 SV=2 5.99 3035.2 - 2.22E+06 - - - -4.9484 - 1.895 0.476 - 287.7 1 2 0 -0.0057 10 0 0 0 7.23E+07 3.67E+07 - - - 4.3392 0.9947 221125_WJC_METTL3_EV_vs_WT_F02.15924.15924.2 0.00463 14-Jul R.NFMIDTYR[166.11].L "sp|Q8TAQ2|SMRC2_HUMAN,sp|Q92922|SMRC1_HUMAN,tr|F8VXC8|F8VXC8_HUMAN" 3 1068.4938 1.07 15678 15924 2 1068.497363 535.2542 SWI\SNF complex subunit SMARCC2 OS=Homo sapiens OX=9606 GN=SMARCC2 PE=1 SV=1 5.84 3035.2 - 4.02E+06 - - - 3.3477 - 1.623 0.267 - 205.1 1 2 0 0.0036 8 0 0 0 8.72E+07 8.14E+07 - - - 2.4725 0.9997 221125_WJC_METTL3_EV_vs_WT_F02.15926.15926.2 0.00332 18-Nov K.C[160.03]VLVWEGTAK[136.11].D sp|O43395|PRPF3_HUMAN 1 1169.5994 2.66 15680 15926 2 1169.597958 585.807 U4\U6 small nuclear ribonucleoprotein Prp3 OS=Homo sapiens OX=9606 GN=PRPF3 PE=1 SV=2 5.99 3035.4 - 1.35E+06 - - - -1.2586 - 1.977 0.383 - 301.2 1 2 0 -0.0015 10 0 0 0 7.16E+07 2.70E+07 - - - 3.7719 0.9994 221125_WJC_METTL3_EV_vs_WT_F02.15927.15927.2 0.00101 20-Dec K.TLVNPANVTFK[136.11].T "sp|O75608|LYPA1_HUMAN,tr|E5RGR0|E5RGR0_HUMAN,tr|A0A087X1K9|A0A087X1K9_HUMAN,tr|B4DP64|B4DP64_HUMAN" 4 1210.6801 0.35 15681 15927 2 1210.683309 606.3473 Acyl-protein thioesterase 1 OS=Homo sapiens OX=9606 GN=LYPLA1 PE=1 SV=1 8.41 3035.6 - 850028 - - - 2.6316 - 2.117 0.429 - 389.4 1 2 0 0.0032 11 0 0 0 6.48E+06 1.84E+07 - - - 4.2375 0.9997 221125_WJC_METTL3_EV_vs_WT_F02.15930.15930.2 0.00101 22-Oct R.LQTSSVLVSGLR[166.11].G "sp|P22314|UBA1_HUMAN,tr|Q5JRS3|Q5JRS3_HUMAN,tr|Q5JRS2|Q5JRS2_HUMAN,tr|Q5JRS0|Q5JRS0_HUMAN,tr|Q5JRS1|Q5JRS1_HUMAN,tr|Q5JRR9|Q5JRR9_HUMAN" 6 1268.7328 0.41 15682 15930 2 1268.733939 635.3737 Ubiquitin-like modifier-activating enzyme 1 OS=Homo sapiens OX=9606 GN=UBA1 PE=1 SV=3 9.75 3036 - 2.65E+06 - - - 0.9206 - 1.826 0.457 - 288.1 1 2 0 0.0012 12 0 0 0 1.96E+07 4.75E+07 - - - 4.0003 0.9986 221125_WJC_METTL3_EV_vs_WT_F02.15933.15933.2 0.0752 14-Aug R.ELVITIAR[166.11].E "sp|Q9NWS0|PIHD1_HUMAN,tr|M0QYF4|M0QYF4_HUMAN,tr|M0QZZ1|M0QZZ1_HUMAN,tr|M0QXD5|M0QXD5_HUMAN,tr|M0R3A4|M0R3A4_HUMAN,tr|M0R028|M0R028_HUMAN,tr|M0QZ61|M0QZ61_HUMAN,tr|M0R2P8|M0R2P8_HUMAN,tr|M0QZM3|M0QZM3_HUMAN,tr|M0QYA2|M0QYA2_HUMAN" 10 923.5679 1.31 15685 15933 2 923.567625 462.7912 PIH1 domain-containing protein 1 OS=Homo sapiens OX=9606 GN=PIH1D1 PE=1 SV=1 6.1 3036.2 - 1.13E+06 - - - -0.3378 - 1.679 0.201 - 299.7 1 2 0 -0.0003 8 0 0 0 2.56E+07 1.96E+07 - - - 2.0884 0.9998 221125_WJC_METTL3_EV_vs_WT_F02.15934.15934.2 1.68E-06 22-Nov K.VLISDSLDPC[160.03]C[160.03]R[166.11].K "sp|O43175|SERA_HUMAN,tr|A0A2C9F2M7|A0A2C9F2M7_HUMAN,tr|A0A286YFB2|A0A286YFB2_HUMAN,tr|A0A286YF34|A0A286YF34_HUMAN,tr|A0A286YFC8|A0A286YFC8_HUMAN,tr|A0A286YF22|A0A286YF22_HUMAN,tr|A0A286YFL2|A0A286YFL2_HUMAN,tr|A0A286YFA2|A0A286YFA2_HUMAN,tr|A0A286YFM8|A0A286YFM8_HUMAN,tr|A0A286YER3|A0A286YER3_HUMAN,tr|A0A286YFF3|A0A286YFF3_HUMAN,tr|A0A286YFK5|A0A286YFK5_HUMAN" 12 1443.6726 1.35 15686 15934 2 1443.673234 722.8436 D-3-phosphoglycerate dehydrogenase OS=Homo sapiens OX=9606 GN=PHGDH PE=1 SV=4 4.21 3036.4 - 551758 - - - 0.4696 - 1.938 0.477 - 310 1 2 0 0.0007 12 0 0 0 1.38E+07 1.02E+07 - - - 4.3048 0.981 221125_WJC_METTL3_EV_vs_WT_F02.15935.15935.2 0.179 20-Aug K.SDAPDTLLLEK.H "sp|P53611|PGTB2_HUMAN,tr|Q5T4U8|Q5T4U8_HUMAN" 2 1200.6238 22.77 15687 15935 2 1200.619896 601.3192 Geranylgeranyl transferase type-2 subunit beta OS=Homo sapiens OX=9606 GN=RABGGTB PE=1 SV=2 4.03 3036.5 - 480540 - - - -3.2383 - 1.373 0.195 - 144 1 2 0 -0.0039 11 0 0 0 1.39E+08 6.11E+06 - - - 1.3376 1 221125_WJC_METTL3_EV_vs_WT_F02.15936.15936.2 1.20E-09 22-Nov K.VLISDSLDPC[160.03]C[160.03]R.K "sp|O43175|SERA_HUMAN,tr|A0A2C9F2M7|A0A2C9F2M7_HUMAN,tr|A0A286YFB2|A0A286YFB2_HUMAN,tr|A0A286YF34|A0A286YF34_HUMAN,tr|A0A286YFC8|A0A286YFC8_HUMAN,tr|A0A286YF22|A0A286YF22_HUMAN,tr|A0A286YFL2|A0A286YFL2_HUMAN,tr|A0A286YFA2|A0A286YFA2_HUMAN,tr|A0A286YFM8|A0A286YFM8_HUMAN,tr|A0A286YER3|A0A286YER3_HUMAN,tr|A0A286YFF3|A0A286YFF3_HUMAN,tr|A0A286YFK5|A0A286YFK5_HUMAN" 12 1433.6643 1.35 15688 15936 2 1433.667398 717.8394 D-3-phosphoglycerate dehydrogenase OS=Homo sapiens OX=9606 GN=PHGDH PE=1 SV=4 4.21 3036.6 - 463425 - - - 2.1707 - 2.404 0.625 - 344.2 1 2 0 0.0031 12 0 0 0 1.38E+07 1.02E+07 - - - 5.9642 0.9592 221125_WJC_METTL3_EV_vs_WT_F02.15937.15937.2 8.72E-05 18-Aug K.YVHYEIDAC[160.03]M.D "sp|Q86U44|MTA70_HUMAN,tr|H0YFV6|H0YFV6_HUMAN" 2 1299.5264 - 15689 15937 2 1299.522414 650.7705 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 4.35 3036.8 - 571064 - - - -3.0634 - 1.685 0.54 - 275 1 1 0 -0.004 10 0 0 0 - - - - - 4.4846 0.9978 221125_WJC_METTL3_EV_vs_WT_F02.15938.15938.2 0.00647 24-Dec K.TMDVIAEGDPGFK[136.11].R "sp|Q9NRY5|F1142_HUMAN,tr|E7ESJ7|E7ESJ7_HUMAN,tr|E5RGF9|E5RGF9_HUMAN" 3 1386.6581 0.75 15690 15938 2 1386.662833 694.3363 Protein FAM114A2 OS=Homo sapiens OX=9606 GN=FAM114A2 PE=1 SV=4 4.03 3036.9 - 304501 - - - 3.437 - 1.85 0.376 - 362.5 1 2 0 0.0048 13 0 0 0 1.43E+07 1.92E+07 - - - 3.3955 0.9999 221125_WJC_METTL3_EV_vs_WT_F02.15942.15942.2 0.000101 13/22 R.LLIVSTTPYSEK.D "sp|Q9Y230|RUVB2_HUMAN,tr|M0R0Y3|M0R0Y3_HUMAN" 2 1349.7442 0.71 15692 15942 2 1349.743768 675.8794 RuvB-like 2 OS=Homo sapiens OX=9606 GN=RUVBL2 PE=1 SV=3 6 3037.4 - 1.41E+06 - - - -0.3445 - 2.437 0.492 - 554.6 1 2 0 -0.0005 12 0 0 0 5.13E+07 7.20E+07 - - - 5.0185 0.9988 221125_WJC_METTL3_EV_vs_WT_F02.15943.15943.2 0.0138 20-Jun R.LMMDPLSGQNR.G "sp|O43390|HNRPR_HUMAN,tr|B4DT28|B4DT28_HUMAN,tr|A0A6Q8PH31|A0A6Q8PH31_HUMAN,tr|A0A6Q8PEX7|A0A6Q8PEX7_HUMAN,tr|A0A6Q8PH35|A0A6Q8PH35_HUMAN" 5 1260.5955 1.01 15693 15943 2 1260.595051 631.305 Heterogeneous nuclear ribonucleoprotein R OS=Homo sapiens OX=9606 GN=HNRNPR PE=1 SV=1 5.84 3037.5 - 2.74E+06 - - - -0.3379 - 1.347 0.321 - 107.9 1 2 0 -0.0004 11 0 0 0 5.35E+07 5.32E+07 - - - 2.2176 0.9995 221125_WJC_METTL3_EV_vs_WT_F02.15944.15944.2 0.00216 20-Aug R.LMMDPLSGQNR[166.11].G "sp|O43390|HNRPR_HUMAN,tr|B4DT28|B4DT28_HUMAN,tr|A0A6Q8PH31|A0A6Q8PH31_HUMAN,tr|A0A6Q8PEX7|A0A6Q8PEX7_HUMAN,tr|A0A6Q8PH35|A0A6Q8PH35_HUMAN" 5 1270.6037 1.01 15694 15944 2 1270.601011 636.3091 Heterogeneous nuclear ribonucleoprotein R OS=Homo sapiens OX=9606 GN=HNRNPR PE=1 SV=1 5.84 3037.5 - 2.23E+06 - - - -2.1533 - 1.611 0.507 - 191.1 1 2 0 -0.0027 11 0 0 0 5.35E+07 5.32E+07 - - - 4.0748 0.9968 221125_WJC_METTL3_EV_vs_WT_F02.15946.15946.2 0.11 14-Aug K.QLLSTIMK[136.11].D "sp|Q9H8H0|NOL11_HUMAN,tr|J3QR28|J3QR28_HUMAN" 2 940.5507 0.99 15696 15946 2 940.551317 471.2826 Nucleolar protein 11 OS=Homo sapiens OX=9606 GN=NOL11 PE=1 SV=1 8.75 3037.7 - 908598 - - - 0.6677 - 1.457 0.184 - 193.1 1 2 0 0.0006 8 0 0 0 1.97E+07 1.99E+07 - - - 1.535 0.9955 221125_WJC_METTL3_EV_vs_WT_F02.15947.15947.2 0.101 24-Aug K.VIGGDDLSTLTGK[136.11].N sp|P00492|HPRT_HUMAN 1 1282.686 0.64 15697 15947 2 1282.686772 642.3503 Hypoxanthine-guanine phosphoribosyltransferase OS=Homo sapiens OX=9606 GN=HPRT1 PE=1 SV=2 4.21 3037.8 - 644049 - - - 0.6042 - 1.608 0.136 - 104.3 1 2 0 0.0008 13 0 0 0 5.07E+06 7.91E+06 - - - 1.2643 0.9958 221125_WJC_METTL3_EV_vs_WT_F02.15951.15951.2 2.90E-06 14/24 K.AAVAVVPLVSEDK[136.11].S sp|O75152|ZC11A_HUMAN 1 1304.7431 1.36 15700 15951 2 1304.739117 653.3788 Zinc finger CCCH domain-containing protein 11A OS=Homo sapiens OX=9606 GN=ZC3H11A PE=1 SV=3 4.37 3038.3 - 1.89E+06 - - - -3.0657 - 2.789 0.108 - 801.7 1 2 0 -0.004 13 0 0 0 4.78E+07 3.51E+07 - - - 2.4699 0.9937 221125_WJC_METTL3_EV_vs_WT_F02.15954.15954.2 1.54 16-Aug K.AIVWGMQTR[166.11].A sp|P53396|ACLY_HUMAN 1 1070.5571 2.47 15702 15954 2 1070.556589 536.2858 ATP-citrate synthase OS=Homo sapiens OX=9606 GN=ACLY PE=1 SV=3 9.79 3038.6 - 1.82E+06 - - - -0.4353 - 1.304 0.155 - 263.1 1 2 0 -0.0005 9 0 0 0 5.61E+07 2.27E+07 - - - 0.9536 0.9986 221125_WJC_METTL3_EV_vs_WT_F02.15955.15955.2 0.0232 14-Aug K.QLLSTIMK.D "sp|Q9H8H0|NOL11_HUMAN,tr|J3QR28|J3QR28_HUMAN" 2 932.5365 1.06 15703 15955 2 932.536094 467.2755 Nucleolar protein 11 OS=Homo sapiens OX=9606 GN=NOL11 PE=1 SV=1 8.75 3038.6 - 1.17E+06 - - - -0.4236 - 1.412 0.269 - 169.1 1 2 0 -0.0004 8 0 0 0 1.92E+07 1.82E+07 - - - 2.0682 0.9999 221125_WJC_METTL3_EV_vs_WT_F02.15957.15957.2 5.73E-08 26-Dec K.IFVGGLNPEATEEK.L "tr|D6R9P3|D6R9P3_HUMAN,tr|D6RD18|D6RD18_HUMAN,tr|D6RBZ0|D6RBZ0_HUMAN" 3 1502.7617 1.49 15705 15957 2 1502.762403 752.3881 Heterogeneous nuclear ribonucleoprotein A\B OS=Homo sapiens OX=9606 GN=HNRNPAB PE=1 SV=1 4.25 3038.9 - 746542 - - - 0.4851 - 2.386 0.588 - 355.6 1 2 0 0.0007 14 0 0 0 7.23E+08 4.87E+08 - - - 5.566 0.9993 221125_WJC_METTL3_EV_vs_WT_F02.15960.15960.3 0.000394 13/40 M.VPPVQVSPLIK.L sp|P56385|ATP5I_HUMAN 1 1175.7278 1.79 15708 15960 3 1175.727937 392.9165 "ATP synthase subunit e, mitochondrial OS=Homo sapiens OX=9606 GN=ATP5ME PE=1 SV=2" 8.72 3039.3 - 498147 - - - 0.1208 - 2.392 0.23 - 250.3 1 2 0 0.0001 11 0 0 0 1.13E+07 6.29E+06 - - - 3.5818 0.9978 221125_WJC_METTL3_EV_vs_WT_F02.15966.15966.2 0.00489 18-Jul K.GVAYTLLTPK[136.11].D "sp|Q86XP3|DDX42_HUMAN,tr|A0A0A0MSJ0|A0A0A0MSJ0_HUMAN" 2 1069.6263 1.51 15712 15966 2 1069.624738 535.8204 ATP-dependent RNA helicase DDX42 OS=Homo sapiens OX=9606 GN=DDX42 PE=1 SV=1 8.59 3040 - 1.80E+06 - - - -1.4575 - 1.39 0.281 - 144 1 2 0 -0.0016 10 0 0 0 8.96E+07 5.92E+07 - - - 2.0352 0.9914 221125_WJC_METTL3_EV_vs_WT_F02.15967.15967.2 0.0269 18-Sep R.IQLVEEELDR.A "sp|P67936|TPM4_HUMAN,sp|P09493|TPM1_HUMAN,sp|P06753|TPM3_HUMAN,sp|P07951|TPM2_HUMAN,tr|A0A0S2Z4G6|A0A0S2Z4G6_HUMAN,tr|A0A494C0G0|A0A494C0G0_HUMAN,tr|A7XZE4|A7XZE4_HUMAN,tr|A0A2R8Y5V9|A0A2R8Y5V9_HUMAN,tr|F5H7S3|F5H7S3_HUMAN,tr|H0YKX5|H0YKX5_HUMAN,tr|Q6ZN40|Q6ZN40_HUMAN,tr|A0A2R8YEU4|A0A2R8YEU4_HUMAN,tr|A0A2R8YGX3|A0A2R8YGX3_HUMAN,tr|A0A2R2Y2Q3|A0A2R2Y2Q3_HUMAN,tr|A0A087WWU8|A0A087WWU8_HUMAN,tr|H0YKJ4|H0YKJ4_HUMAN,tr|H0YK48|H0YK48_HUMAN,tr|H0YL80|H0YL80_HUMAN,tr|K7ENT6|K7ENT6_HUMAN,tr|J3KN67|J3KN67_HUMAN,tr|A0A494C0P6|A0A494C0P6_HUMAN,tr|D6R904|D6R904_HUMAN,tr|A0A2R8YH90|A0A2R8YH90_HUMAN,tr|B7Z596|B7Z596_HUMAN,tr|H0YKP3|H0YKP3_HUMAN,tr|A0A494BZZ2|A0A494BZZ2_HUMAN,tr|Q5TCU3|Q5TCU3_HUMAN,tr|A0A2R8YE05|A0A2R8YE05_HUMAN,tr|A0A2R8YHD2|A0A2R8YHD2_HUMAN,tr|H7BYY1|H7BYY1_HUMAN" 30 1242.6456 1.34 15713 15967 2 1242.639833 622.3301 Tropomyosin alpha-4 chain OS=Homo sapiens OX=9606 GN=TPM4 PE=1 SV=3 4 3040 - 3.02E+06 - - - -4.6264 - 1.875 0.279 - 303.6 1 2 0 -0.0057 10 0 0 0 2.79E+08 2.08E+08 - - - 2.8545 0.9998 221125_WJC_METTL3_EV_vs_WT_F02.15968.15968.2 0.00273 18-Aug K.GFYIYQEGVK.R "sp|P40939|ECHA_HUMAN,tr|H0YFD6|H0YFD6_HUMAN,tr|A0A2R8Y4F5|A0A2R8Y4F5_HUMAN" 3 1202.5972 1.46 15714 15968 2 1202.597202 602.3059 "Trifunctional enzyme subunit alpha, mitochondrial OS=Homo sapiens OX=9606 GN=HADHA PE=1 SV=2" 6 3040.1 - 2.37E+06 - - - 0.0225 - 1.851 0.422 - 150.5 1 2 0 0 10 0 0 0 8.42E+07 5.77E+07 - - - 3.8766 0.9999 221125_WJC_METTL3_EV_vs_WT_F02.15969.15969.2 4.50E-07 14/24 K.TMDVIAEGDPGFK.R "sp|Q9NRY5|F1142_HUMAN,tr|E7ESJ7|E7ESJ7_HUMAN,tr|E5RGF9|E5RGF9_HUMAN" 3 1378.6439 0.75 15715 15969 2 1378.644853 690.3292 Protein FAM114A2 OS=Homo sapiens OX=9606 GN=FAM114A2 PE=1 SV=4 4.03 3040.2 - 844218 - - - 0.7152 - 2.352 0.522 - 545 1 2 0 0.001 13 0 0 0 1.43E+07 1.92E+07 - - - 5.0912 0.9997 221125_WJC_METTL3_EV_vs_WT_F02.15970.15970.2 0.0034 18-Sep R.IVILEYQPSK.N "sp|Q15393|SF3B3_HUMAN,tr|J3QL37|J3QL37_HUMAN,tr|J3QRB2|J3QRB2_HUMAN" 3 1188.6754 1.13 15716 15970 2 1188.675608 595.345 Splicing factor 3B subunit 3 OS=Homo sapiens OX=9606 GN=SF3B3 PE=1 SV=4 6 3040.3 - 593072 - - - 0.154 - 1.71 0.4 - 149.9 1 2 0 0.0002 10 0 0 0 8.78E+07 7.74E+07 - - - 3.4929 0.9993 221125_WJC_METTL3_EV_vs_WT_F02.15971.15971.2 0.00408 28-Dec R.MGPAMGPALGAGIER.M "sp|P52272|HNRPM_HUMAN,tr|M0R2I7|M0R2I7_HUMAN,tr|M0QY96|M0QY96_HUMAN,tr|A0A087X0X3|A0A087X0X3_HUMAN,tr|M0QZM1|M0QZM1_HUMAN" 5 1426.7061 1.69 15717 15971 2 1426.701064 714.3603 Heterogeneous nuclear ribonucleoprotein M OS=Homo sapiens OX=9606 GN=HNRNPM PE=1 SV=3 5.75 3040.5 - 451630 - - - -3.5228 - 2.417 0.527 - 261 1 2 0 -0.005 15 0 0 0 5.67E+08 3.36E+08 - - - 5.1016 0.9996 221125_WJC_METTL3_EV_vs_WT_F02.15973.15973.2 0.0171 24-Nov R.LEEGPPVTTVLTR.E "sp|P08559|ODPA_HUMAN,sp|P29803|ODPAT_HUMAN,tr|Q5JPT9|Q5JPT9_HUMAN,tr|Q5JPU0|Q5JPU0_HUMAN,tr|Q5JPU1|Q5JPU1_HUMAN,tr|Q5JPU2|Q5JPU2_HUMAN" 6 1410.7718 1.45 15719 15973 2 1410.774417 706.3932 "Pyruvate dehydrogenase E1 component subunit alpha, somatic form, mitochondrial OS=Homo sapiens OX=9606 GN=PDHA1 PE=1 SV=3" 4.53 3040.7 - 361082 - - - 1.8231 - 2.193 0.44 - 246.1 1 2 0 0.0026 13 0 0 0 1.45E+07 9.94E+06 - - - 4.3055 0.8793 221125_WJC_METTL3_EV_vs_WT_F02.15976.15976.2 1.27 16-Sep N.LLIYLLNKK[136.11].F "sp|Q13576|IQGA2_HUMAN,tr|F5H7S7|F5H7S7_HUMAN" 2 1124.7413 - 15720 15976 2 1124.741134 563.3779 Ras GTPase-activating-like protein IQGAP2 OS=Homo sapiens OX=9606 GN=IQGAP2 PE=1 SV=4 9.7 3041.1 - 2.55E+06 - - - -0.1182 - 1.797 0.128 - 181.9 1 1 0 -0.0001 9 0 0 0 - - - - - 1.682 0.9998 221125_WJC_METTL3_EV_vs_WT_F02.15978.15978.2 0.000364 18-Oct K.GVAYTLLTPK.D "sp|Q86XP3|DDX42_HUMAN,tr|A0A0A0MSJ0|A0A0A0MSJ0_HUMAN" 2 1061.6121 1.47 15722 15978 2 1061.611493 531.8133 ATP-dependent RNA helicase DDX42 OS=Homo sapiens OX=9606 GN=DDX42 PE=1 SV=1 8.59 3041.2 - 3.13E+06 - - - -0.5689 - 1.891 0.445 - 318.7 1 2 0 -0.0006 10 0 0 0 8.71E+07 5.92E+07 - - - 4.1059 0.9998 221125_WJC_METTL3_EV_vs_WT_F02.15979.15979.3 0.397 13/40 K.LTLLHYDPVVK.Q sp|O75394|RM33_HUMAN 1 1296.7442 1.1 15723 15979 3 1296.745201 433.2553 "39S ribosomal protein L33, mitochondrial OS=Homo sapiens OX=9606 GN=MRPL33 PE=1 SV=1" 6.74 3041.3 - 1.70E+06 - - - 0.792 - 2.616 0.31 - 357.7 1 2 0 0.001 11 0 0 0 1.04E+08 9.39E+07 - - - 4.7278 0.9999 221125_WJC_METTL3_EV_vs_WT_F02.15980.15980.3 0.00108 Dec-40 K.LTLLHYDPVVK[136.11].Q sp|O75394|RM33_HUMAN 1 1304.7584 1.1 15724 15980 3 1304.75982 435.9267 "39S ribosomal protein L33, mitochondrial OS=Homo sapiens OX=9606 GN=MRPL33 PE=1 SV=1" 6.74 3041.4 - 1.61E+06 - - - 1.1083 - 2.465 0.376 - 269.9 1 2 0 0.0014 11 0 0 0 1.04E+08 9.39E+07 - - - 5.2946 0.9695 221125_WJC_METTL3_EV_vs_WT_F02.15983.15983.2 0.0534 20-Jul K.VFDPVPVGVTK.V sp|Q08211|DHX9_HUMAN 1 1156.6492 0.99 15727 15983 2 1156.648499 579.3319 ATP-dependent RNA helicase A OS=Homo sapiens OX=9606 GN=DHX9 PE=1 SV=4 5.81 3041.8 - 620674 - - - -0.6156 - 1.383 0.018 - 109.6 2 2 0 -0.0007 11 0 0 0 1.66E+08 1.68E+08 - - - -0.0836 0.9895 221125_WJC_METTL3_EV_vs_WT_F02.15984.15984.2 0.0103 22-Sep S.LADLQNDEVAFR[166.11].K "sp|P61247|RS3A_HUMAN,tr|H0Y8L7|H0Y8L7_HUMAN,tr|D6RI02|D6RI02_HUMAN,tr|D6RED7|D6RED7_HUMAN,tr|D6RGE0|D6RGE0_HUMAN,tr|D6RAS7|D6RAS7_HUMAN,tr|D6RB09|D6RB09_HUMAN,tr|E9PFI5|E9PFI5_HUMAN,tr|D6RAT0|D6RAT0_HUMAN,tr|D6RG13|D6RG13_HUMAN" 10 1399.6971 1.51 15728 15984 2 1399.696876 700.8558 40S ribosomal protein S3a OS=Homo sapiens OX=9606 GN=RPS3A PE=1 SV=2 4.03 3042 - 368171 - - - -0.17 - 2.172 0.428 - 363.6 1 1 0 -0.0002 12 0 0 0 6.94E+06 4.60E+06 - - - 4.243 0.8749 221125_WJC_METTL3_EV_vs_WT_F02.15990.15990.3 0.0415 Jul-40 K.EFKAELILYR[166.11]K.S "sp|Q9ULD8|KCNH3_HUMAN,tr|A0A3B3ITH0|A0A3B3ITH0_HUMAN" 2 1418.8161 - 15732 15990 3 1418.824436 473.946 Potassium voltage-gated channel subfamily H member 3 OS=Homo sapiens OX=9606 GN=KCNH3 PE=1 SV=2 8.59 3042.7 - 4.67E+06 - - - 5.8711 - 1.739 0.285 - 39.5 1 2 1 0.0083 11 0 0 0 - - - - - 3.287 0.9997 221125_WJC_METTL3_EV_vs_WT_F02.15991.15991.2 0.000356 16-Sep R.GLATFC[160.03]LDK.D "sp|O15173|PGRC2_HUMAN,sp|O00264|PGRC1_HUMAN,tr|U3KQM0|U3KQM0_HUMAN" 3 1023.5059 1.11 15733 15991 2 1023.506536 512.7602 Membrane-associated progesterone receptor component 2 OS=Homo sapiens OX=9606 GN=PGRMC2 PE=1 SV=1 5.83 3042.7 - 3.14E+06 - - - 0.6048 - 1.896 0.393 - 257.4 1 2 0 0.0006 9 0 0 0 1.29E+08 1.15E+08 - - - 3.7943 0.9995 221125_WJC_METTL3_EV_vs_WT_F02.15998.15998.2 0.00109 20-Sep K.VFDPVPVGVTK[136.11].V sp|Q08211|DHX9_HUMAN 1 1164.6634 1 15738 15998 2 1164.663596 583.339 ATP-dependent RNA helicase A OS=Homo sapiens OX=9606 GN=DHX9 PE=1 SV=4 5.81 3043.6 - 2.11E+06 - - - 0.1588 - 1.673 0.344 - 233.2 1 2 0 0.0002 11 0 0 0 1.62E+08 1.63E+08 - - - 2.9739 0.9955 221125_WJC_METTL3_EV_vs_WT_F02.15999.15999.2 0.151 12-Jun R.DLTWYAK.G sp|Q9BU76|MMTA2_HUMAN 1 895.444 0.72 15739 15999 2 895.445204 448.7293 Multiple myeloma tumor-associated protein 2 OS=Homo sapiens OX=9606 GN=MMTAG2 PE=1 SV=1 5.83 3043.7 - 816969 - - - 1.3792 - 1.061 0.312 - 141.1 1 2 0 0.0012 7 0 0 0 1.61E+07 2.23E+07 - - - 1.5327 0.9977 221125_WJC_METTL3_EV_vs_WT_F02.16000.16000.2 0.0406 20-Jul K.LYEPDQLQELK.L "sp|Q9NZB2|F120A_HUMAN,tr|A0A0C4DG79|A0A0C4DG79_HUMAN" 2 1374.7031 0.72 15740 16000 2 1374.70363 688.3588 Constitutive coactivator of PPAR-gamma-like protein 1 OS=Homo sapiens OX=9606 GN=FAM120A PE=1 SV=2 4.14 3043.8 - 1.01E+06 - - - 0.3877 - 1.333 0.257 - 93.3 1 2 0 0.0005 11 0 0 0 2.67E+07 3.71E+07 - - - 1.7166 0.9998 221125_WJC_METTL3_EV_vs_WT_F02.16001.16001.2 0.00108 15/20 K.LADIQIEQLNR[166.11].T "sp|O60925|PFD1_HUMAN,tr|E5RGS4|E5RGS4_HUMAN" 2 1321.7229 1.82 15741 16001 2 1321.723677 661.8687 Prefoldin subunit 1 OS=Homo sapiens OX=9606 GN=PFDN1 PE=1 SV=2 4.37 3043.9 - 806514 - - - 0.5621 - 2.712 0.377 - 638 1 2 0 0.0007 11 0 0 0 3.08E+07 1.69E+07 - - - 4.5243 0.9994 221125_WJC_METTL3_EV_vs_WT_F02.16002.16002.2 4.97E-05 22-Oct K.IVYPPQLPGEPR.R "sp|Q9NWU5|RM22_HUMAN,tr|E7ESL0|E7ESL0_HUMAN,tr|J3KQY1|J3KQY1_HUMAN" 3 1364.7452 2.26 15742 16002 2 1364.744498 683.3799 "39S ribosomal protein L22, mitochondrial OS=Homo sapiens OX=9606 GN=MRPL22 PE=1 SV=1" 6 3044 - 466041 - - - -0.5408 - 1.916 0.289 - 358.1 1 2 0 -0.0007 12 0 0 0 1.56E+07 6.89E+06 - - - 2.8862 0.9997 221125_WJC_METTL3_EV_vs_WT_F02.16006.16006.2 0.00318 16-Sep K.DVDGVFLSK.M sp|Q8N1N4|K2C78_HUMAN 1 978.5022 5.34 15744 16006 2 978.502285 490.2584 "Keratin, type II cytoskeletal 78 OS=Homo sapiens OX=9606 GN=KRT78 PE=1 SV=2" 4.21 3044.6 - 8.94E+06 - - - 0.0746 - 1.67 0.439 - 184.5 1 2 0 0.0001 9 0 0 0 1.59E+08 2.98E+07 - - - 3.7671 0.9998 221125_WJC_METTL3_EV_vs_WT_F02.16007.16007.2 0.000157 20-Nov K.FVELPGAEMGK[136.11].V "sp|P07814|SYEP_HUMAN,tr|V9GYZ6|V9GYZ6_HUMAN" 2 1184.5991 0.9 15745 16007 2 1184.600426 593.3068 Bifunctional glutamate\proline--tRNA ligase OS=Homo sapiens OX=9606 GN=EPRS1 PE=1 SV=5 4.53 3044.6 - 2.57E+06 - - - 1.1227 - 1.892 0.504 - 406.7 1 2 0 0.0013 11 0 0 0 8.29E+07 9.21E+07 - - - 4.4881 0.9993 221125_WJC_METTL3_EV_vs_WT_F02.16009.16009.2 0.0178 16-Jul R.ITDLYTDLR.D "sp|Q01082|SPTB2_HUMAN,tr|A0A087WUZ3|A0A087WUZ3_HUMAN,tr|F8W6C1|F8W6C1_HUMAN" 3 1108.5764 1.02 15747 16009 2 1108.577744 555.2955 "Spectrin beta chain, non-erythrocytic 1 OS=Homo sapiens OX=9606 GN=SPTBN1 PE=1 SV=2" 4.21 3044.7 - 1.55E+06 - - - 1.1763 - 1.911 0.285 - 134.9 1 2 0 0.0013 9 0 0 0 4.02E+07 3.94E+07 - - - 3.0192 0.9998 221125_WJC_METTL3_EV_vs_WT_F02.16012.16012.2 1.72E-05 24-Jul R.LLVVDQETDEELR.R "sp|Q15599|NHRF2_HUMAN,tr|H3BMF5|H3BMF5_HUMAN" 2 1557.7886 0.87 15750 16012 2 1557.787959 779.9016 Na(+)\H(+) exchange regulatory cofactor NHE-RF2 OS=Homo sapiens OX=9606 GN=SLC9A3R2 PE=1 SV=2 3.83 3045.1 - 133696 - - - -0.4224 - 1.747 0.522 - 97.2 1 2 0 -0.0007 13 0 0 0 9.10E+05 1.04E+06 - - - 4.3282 0.9999 221125_WJC_METTL3_EV_vs_WT_F02.16016.16016.2 6.52E-08 20-Nov K.AMTGVEQWPYR[166.11].A "sp|P49368|TCPG_HUMAN,tr|B4DUR8|B4DUR8_HUMAN" 2 1346.6317 0.16 15752 16016 2 1346.632052 674.3231 T-complex protein 1 subunit gamma OS=Homo sapiens OX=9606 GN=CCT3 PE=1 SV=4 6.05 3045.6 - 2.01E+06 - - - 0.2792 - 2.173 0.535 - 584.8 1 2 0 0.0004 11 0 0 0 2.17E+07 1.32E+08 - - - 5.0919 0.9999 221125_WJC_METTL3_EV_vs_WT_F02.16017.16017.2 6.08E-05 18-Nov R.EGPLC[160.03]DELIR.N "sp|Q15029|U5S1_HUMAN,tr|K7EJ74|K7EJ74_HUMAN,tr|K7EP67|K7EP67_HUMAN" 3 1200.5809 2.33 15753 16017 2 1200.58208 601.2977 116 kDa U5 small nuclear ribonucleoprotein component OS=Homo sapiens OX=9606 GN=EFTUD2 PE=1 SV=1 4.14 3045.7 - 5.85E+06 - - - 1.0053 - 2.027 0.588 - 530.4 1 2 0 0.0012 10 0 0 0 2.08E+08 8.94E+07 - - - 5.3558 0.9982 221125_WJC_METTL3_EV_vs_WT_F02.16018.16018.2 0.068 16-Aug R.ITDLYTDLR[166.11].D "sp|Q01082|SPTB2_HUMAN,tr|A0A087WUZ3|A0A087WUZ3_HUMAN,tr|F8W6C1|F8W6C1_HUMAN" 3 1118.5847 1.03 15754 16018 2 1118.582112 560.2996 "Spectrin beta chain, non-erythrocytic 1 OS=Homo sapiens OX=9606 GN=SPTBN1 PE=1 SV=2" 4.21 3045.7 - 1.93E+06 - - - -2.3226 - 1.938 0.24 - 165.3 1 2 0 -0.0026 9 0 0 0 4.07E+07 3.95E+07 - - - 2.727 0.9995 221125_WJC_METTL3_EV_vs_WT_F02.16019.16019.2 0.00981 12-Jul R.GNSLFFR.K sp|Q9Y6C9|MTCH2_HUMAN 1 839.429 0.83 15755 16019 2 839.42863 420.7218 Mitochondrial carrier homolog 2 OS=Homo sapiens OX=9606 GN=MTCH2 PE=1 SV=1 9.75 3045.9 - 657677 - - - -0.4253 - 1.473 0.386 - 251.3 1 2 0 -0.0004 7 0 0 0 2.23E+07 2.67E+07 - - - 3.1191 0.9987 221125_WJC_METTL3_EV_vs_WT_F02.16020.16020.2 0.000245 16-Sep R.MGPNIYELR[166.11].T "sp|Q9BPW8|NIPS1_HUMAN,tr|C9JDV8|C9JDV8_HUMAN,tr|H7C2U6|H7C2U6_HUMAN" 3 1101.5516 1.36 15756 16020 2 1101.554993 551.7831 Protein NipSnap homolog 1 OS=Homo sapiens OX=9606 GN=NIPSNAP1 PE=1 SV=1 5.75 3045.9 - 552233 - - - 3.0484 - 1.822 0.392 - 257.8 1 2 0 0.0034 9 0 0 0 3.45E+07 2.53E+07 - - - 3.6709 0.9996 221125_WJC_METTL3_EV_vs_WT_F02.16025.16025.2 3.82E-05 18-Nov R.EGPLC[160.03]DELIR[166.11].N "sp|Q15029|U5S1_HUMAN,tr|K7EJ74|K7EJ74_HUMAN,tr|K7EP67|K7EP67_HUMAN" 3 1210.5891 2.25 15759 16025 2 1210.590322 606.3018 116 kDa U5 small nuclear ribonucleoprotein component OS=Homo sapiens OX=9606 GN=EFTUD2 PE=1 SV=1 4.14 3046.6 - 4.87E+06 - - - 0.9739 - 1.864 0.372 - 402.9 1 2 0 0.0012 10 0 0 0 2.00E+08 8.91E+07 - - - 3.5264 0.9957 221125_WJC_METTL3_EV_vs_WT_F02.16026.16026.2 0.1 16-Jun R.EGPFYPTLR[166.11].L sp|Q9ULC4|MCTS1_HUMAN 1 1088.553 0.25 15760 16026 2 1088.553968 545.2838 Malignant T-cell-amplified sequence 1 OS=Homo sapiens OX=9606 GN=MCTS1 PE=1 SV=1 6.1 3046.7 - 785945 - - - 0.8755 - 1.135 0.267 - 139.5 1 2 0 0.001 9 0 0 0 6.79E+06 2.75E+07 - - - 1.3791 0.9994 221125_WJC_METTL3_EV_vs_WT_F02.16027.16027.2 0.0742 20-Oct K.FVELPGAEMGK.V "sp|P07814|SYEP_HUMAN,tr|V9GYZ6|V9GYZ6_HUMAN" 2 1176.5849 0.9 15761 16027 2 1176.585543 589.2997 Bifunctional glutamate\proline--tRNA ligase OS=Homo sapiens OX=9606 GN=EPRS1 PE=1 SV=5 4.53 3046.7 - 3.97E+06 - - - 0.5499 - 1.713 0.323 - 318 1 2 0 0.0006 11 0 0 0 8.28E+07 9.21E+07 - - - 2.8826 0.999 221125_WJC_METTL3_EV_vs_WT_F02.16029.16029.2 0.0194 14-Aug K.TLFETIER[166.11].S sp|Q9H5Q4|TFB2M_HUMAN 1 1017.537 0.53 15763 16029 2 1017.537484 509.7758 "Dimethyladenosine transferase 2, mitochondrial OS=Homo sapiens OX=9606 GN=TFB2M PE=1 SV=1" 4.53 3046.9 - 677115 - - - 0.4452 - 1.343 0.34 - 231.4 1 2 0 0.0005 8 0 0 0 7.76E+06 1.45E+07 - - - 2.4415 0.9887 221125_WJC_METTL3_EV_vs_WT_F02.16030.16030.2 0.0173 16-Aug K.DLSTIEPLK[136.11].Q "sp|O43423|AN32C_HUMAN,sp|O95626|AN32D_HUMAN,sp|Q92688|AN32B_HUMAN,sp|P39687|AN32A_HUMAN,tr|H0YN26|H0YN26_HUMAN" 5 1022.5739 1 15764 16030 2 1022.57834 512.2942 Acidic leucine-rich nuclear phosphoprotein 32 family member C OS=Homo sapiens OX=9606 GN=ANP32C PE=2 SV=1 4.37 3047 - 363264 - - - 4.3156 - 1.513 0.295 - 160.4 1 2 0 0.0044 9 0 0 0 3.66E+07 3.65E+07 - - - 2.4165 1 221125_WJC_METTL3_EV_vs_WT_F02.16036.16036.2 5.33E-08 15/28 R.MGPAMGPALGAGIER[166.11].M "sp|P52272|HNRPM_HUMAN,tr|M0R2I7|M0R2I7_HUMAN,tr|M0QY96|M0QY96_HUMAN,tr|A0A087X0X3|A0A087X0X3_HUMAN,tr|M0QZM1|M0QZM1_HUMAN" 5 1436.7144 1.69 15768 16036 2 1436.714248 719.3645 Heterogeneous nuclear ribonucleoprotein M OS=Homo sapiens OX=9606 GN=HNRNPM PE=1 SV=3 5.75 3047.7 - 8.58E+06 - - - -0.078 - 2.689 0.616 - 639.1 1 2 0 -0.0001 15 0 0 0 5.67E+08 3.36E+08 - - - 6.0227 0.9999 221125_WJC_METTL3_EV_vs_WT_F02.16039.16039.2 0.000459 20-Nov K.AMTGVEQWPYR.A "sp|P49368|TCPG_HUMAN,tr|B4DUR8|B4DUR8_HUMAN" 2 1336.6234 0.16 15771 16039 2 1336.622875 669.319 T-complex protein 1 subunit gamma OS=Homo sapiens OX=9606 GN=CCT3 PE=1 SV=4 6.05 3048 - 656082 - - - -0.3973 - 2.241 0.452 - 509.3 1 2 0 -0.0005 11 0 0 0 1.83E+07 1.13E+08 - - - 4.5622 0.9985 221125_WJC_METTL3_EV_vs_WT_F02.16043.16043.2 0.0236 14-Aug K.TLFETIER.S sp|Q9H5Q4|TFB2M_HUMAN 1 1007.5288 0.47 15774 16043 2 1007.529538 504.7717 "Dimethyladenosine transferase 2, mitochondrial OS=Homo sapiens OX=9606 GN=TFB2M PE=1 SV=1" 4.53 3048.5 - 666996 - - - 0.7712 - 1.316 0.315 - 238.1 1 2 0 0.0008 8 0 0 0 7.93E+06 1.68E+07 - - - 2.1955 0.9986 221125_WJC_METTL3_EV_vs_WT_F02.16044.16044.2 0.0485 12-Jul R.MTLDDFR.L "sp|P35527|K1C9_HUMAN,tr|K7EQQ3|K7EQQ3_HUMAN" 2 896.4062 287.41 15775 16044 2 896.407216 449.2104 "Keratin, type I cytoskeletal 9 OS=Homo sapiens OX=9606 GN=KRT9 PE=1 SV=3" 4.21 3048.6 - 567098 - - - 1.1301 - 1.383 0.316 - 191.5 1 2 0 0.001 7 0 0 0 1.47E+07 5.12E+04 - - - 2.4021 0.9978 221125_WJC_METTL3_EV_vs_WT_F02.16045.16045.2 0.0689 12-Jul R.GNSLFFR[166.11].K sp|Q9Y6C9|MTCH2_HUMAN 1 849.4373 0.83 15776 16045 2 849.438259 425.7259 Mitochondrial carrier homolog 2 OS=Homo sapiens OX=9606 GN=MTCH2 PE=1 SV=1 9.75 3048.7 - 1.97E+06 - - - 1.1796 - 1.513 0.222 - 274.6 1 2 0 0.001 7 0 0 0 2.24E+07 2.68E+07 - - - 1.9925 0.9999 221125_WJC_METTL3_EV_vs_WT_F02.16048.16048.2 3.28E-07 20-Dec R.NPLVAVYYTNR[166.11].A sp|Q9UNE7|CHIP_HUMAN 1 1318.6909 0.22 15779 16048 2 1318.692063 660.3527 E3 ubiquitin-protein ligase CHIP OS=Homo sapiens OX=9606 GN=STUB1 PE=1 SV=2 8.59 3048.9 - 1.08E+06 - - - 0.8774 - 2.765 0.46 - 707.4 1 2 0 0.0012 11 0 0 0 6.49E+06 3.00E+07 - - - 5.1895 0.9989 221125_WJC_METTL3_EV_vs_WT_F02.16050.16050.2 8.43E-06 24-Nov R.LEEGPPVTTVLTR[166.11].E "sp|P08559|ODPA_HUMAN,sp|P29803|ODPAT_HUMAN,tr|Q5JPT9|Q5JPT9_HUMAN,tr|Q5JPU0|Q5JPU0_HUMAN,tr|Q5JPU1|Q5JPU1_HUMAN,tr|Q5JPU2|Q5JPU2_HUMAN" 6 1420.7801 1.45 15781 16050 2 1420.774823 711.3973 "Pyruvate dehydrogenase E1 component subunit alpha, somatic form, mitochondrial OS=Homo sapiens OX=9606 GN=PDHA1 PE=1 SV=3" 4.53 3049.2 - 542296 - - - -3.7247 - 1.988 0.512 - 241.8 1 2 0 -0.0053 13 0 0 0 2.58E+07 1.78E+07 - - - 4.5845 0.9998 221125_WJC_METTL3_EV_vs_WT_F02.16051.16051.2 0.0004 22-Oct K.WVPVVDPQEEER.R "sp|Q8WUZ0|BCL7C_HUMAN,tr|I3L1Q2|I3L1Q2_HUMAN" 2 1481.7151 1.37 15782 16051 2 1481.714437 741.8648 B-cell CLL\lymphoma 7 protein family member C OS=Homo sapiens OX=9606 GN=BCL7C PE=1 SV=3 4 3049.3 - 491213 - - - -0.4191 - 1.588 0.538 - 290.5 1 2 0 -0.0006 12 0 0 0 9.54E+06 6.97E+06 - - - 4.2313 0.9976 221125_WJC_METTL3_EV_vs_WT_F02.16052.16052.2 0.0104 22-Jul K.WVPVVDPQEEER[166.11].R "sp|Q8WUZ0|BCL7C_HUMAN,tr|I3L1Q2|I3L1Q2_HUMAN" 2 1491.7233 1.34 15783 16052 2 1491.720479 746.8689 B-cell CLL\lymphoma 7 protein family member C OS=Homo sapiens OX=9606 GN=BCL7C PE=1 SV=3 4 3049.4 - 263221 - - - -1.9099 - 1.165 0.377 - 86.1 1 2 0 -0.0028 12 0 0 0 9.31E+06 6.97E+06 - - - 2.2265 0.9984 221125_WJC_METTL3_EV_vs_WT_F02.16055.16055.2 0.397 20-Oct K.LESELANFGPR.L "sp|Q14683|SMC1A_HUMAN,tr|G8JLG1|G8JLG1_HUMAN,tr|A0A6Q8PHC3|A0A6Q8PHC3_HUMAN" 3 1231.6197 28 15785 16055 2 1231.621826 616.8171 Structural maintenance of chromosomes protein 1A OS=Homo sapiens OX=9606 GN=SMC1A PE=1 SV=2 4.53 3049.8 - 805785 - - - 1.7254 - 1.874 0.249 - 208.2 1 2 0 0.0021 11 0 0 0 7.38E+06 2.64E+05 - - - 2.5785 0.9985 221125_WJC_METTL3_EV_vs_WT_F02.16057.16057.2 0.00664 18-Oct K.AGLSQSLFER[166.11].L sp|Q92900|RENT1_HUMAN 1 1116.5803 1.24 15786 16057 2 1116.57719 559.2974 Regulator of nonsense transcripts 1 OS=Homo sapiens OX=9606 GN=UPF1 PE=1 SV=2 6.05 3050 - 4.88E+06 - - - -2.779 - 2.309 0.26 - 252.1 1 2 0 -0.0031 10 0 0 0 8.42E+07 6.80E+07 - - - 3.2962 0.9995 221125_WJC_METTL3_EV_vs_WT_F02.16058.16058.2 0.00461 14-Jul R.EFADFEYR[166.11].K "sp|Q8ND56|LS14A_HUMAN,tr|A0A140TA66|A0A140TA66_HUMAN,tr|A0A096LP11|A0A096LP11_HUMAN,tr|A0A0G2JQ95|A0A0G2JQ95_HUMAN" 4 1085.4693 1.01 15787 16058 2 1085.4708 543.7419 Protein LSM14 homolog A OS=Homo sapiens OX=9606 GN=LSM14A PE=1 SV=3 4.14 3050.1 - 4.95E+06 - - - 1.3404 - 1.47 0.444 - 278.4 1 2 0 0.0015 8 0 0 0 4.58E+09 4.55E+09 - - - 3.4819 0.9996 221125_WJC_METTL3_EV_vs_WT_F02.16059.16059.2 0.0015 14-Jun R.EFADFEYR.K "sp|Q8ND56|LS14A_HUMAN,tr|A0A140TA66|A0A140TA66_HUMAN,tr|A0A096LP11|A0A096LP11_HUMAN,tr|A0A0G2JQ95|A0A0G2JQ95_HUMAN" 4 1075.4611 1.01 15788 16059 2 1075.462291 538.7378 Protein LSM14 homolog A OS=Homo sapiens OX=9606 GN=LSM14A PE=1 SV=3 4.14 3050.1 - 3.70E+06 - - - 1.1307 - 1.431 0.487 - 192.2 1 2 0 0.0012 8 0 0 0 4.58E+09 4.55E+09 - - - 3.7184 0.9965 221125_WJC_METTL3_EV_vs_WT_F02.16062.16062.2 0.078 14-Aug R.DGAWGAFR[166.11].H "sp|P49327|FAS_HUMAN,tr|A0A0U1RQF0|A0A0U1RQF0_HUMAN" 2 888.4118 0.59 15791 16062 2 888.413037 445.2132 Fatty acid synthase OS=Homo sapiens OX=9606 GN=FASN PE=1 SV=3 5.84 3050.4 - 722834 - - - 1.425 - 1.332 0.248 - 299.1 1 2 0 0.0013 8 0 0 0 2.06E+07 3.46E+07 - - - 1.7369 0.9928 221125_WJC_METTL3_EV_vs_WT_F02.16063.16063.2 0.552 14-Jul K.EIILQGLK.H "sp|Q9Y2L1|RRP44_HUMAN,tr|F2Z2C0|F2Z2C0_HUMAN,tr|G3V1J5|G3V1J5_HUMAN" 3 912.5644 1.89 15792 16063 2 912.564475 457.2895 Exosome complex exonuclease RRP44 OS=Homo sapiens OX=9606 GN=DIS3 PE=1 SV=2 6.1 3050.6 - 679436 - - - 0.0625 - 1.348 0.122 - 121.5 1 2 0 0.0001 8 0 0 0 7.88E+06 4.17E+06 - - - 0.8427 0.9851 221125_WJC_METTL3_EV_vs_WT_F02.16068.16068.2 0.00406 16-Jun R.QPTPPFFGR.D sp|Q96PK6|RBM14_HUMAN 1 1045.5345 1.91 15796 16068 2 1045.539323 523.7745 RNA-binding protein 14 OS=Homo sapiens OX=9606 GN=RBM14 PE=1 SV=2 9.75 3051.2 - 9.03E+06 - - - 4.5986 - 1.174 0.386 - 140.8 1 2 0 0.0048 9 0 0 0 1.16E+09 6.06E+08 - - - 2.3546 0.9998 221125_WJC_METTL3_EV_vs_WT_F02.16070.16070.2 0.00617 14-Sep R.C[160.03]EDIC[160.03]WIK[136.11].T "sp|Q9HCE5|MET14_HUMAN,tr|D6RBL4|D6RBL4_HUMAN" 2 1130.498 0 15797 16070 2 1130.497947 566.2563 N6-adenosine-methyltransferase non-catalytic subunit OS=Homo sapiens OX=9606 GN=METTL14 PE=1 SV=2 4.37 3051.4 - 2.45E+06 - - - -0.0487 - 2.022 0.357 - 361.9 1 2 0 -0.0001 8 0 0 0 7.20E+04 2.62E+07 - - - 3.8013 0.9998 221125_WJC_METTL3_EV_vs_WT_F02.16072.16072.2 0.0023 16-Sep R.YWLEEAEC[160.03]R.D "sp|P55884|EIF3B_HUMAN,tr|C9JQN7|C9JQN7_HUMAN,tr|C9JZG1|C9JZG1_HUMAN" 3 1254.5339 1.14 15799 16072 2 1254.533696 628.2742 Eukaryotic translation initiation factor 3 subunit B OS=Homo sapiens OX=9606 GN=EIF3B PE=1 SV=3 4.25 3051.6 - 1.34E+06 - - - -0.1809 - 1.871 0.456 - 434.7 1 2 0 -0.0002 9 0 0 0 1.65E+07 1.45E+07 - - - 4.2214 0.8207 221125_WJC_METTL3_EV_vs_WT_F02.16073.16073.2 0.196 18-Aug K.HTGPGLLSMA.N "sp|P49792|RBP2_HUMAN,sp|Q9UNP9|PPIE_HUMAN,sp|P62937|PPIA_HUMAN,tr|E9PEQ6|E9PEQ6_HUMAN,tr|C9J5S7|C9J5S7_HUMAN,tr|E9PKY5|E9PKY5_HUMAN,tr|A0A7I2V4V1|A0A7I2V4V1_HUMAN,tr|F8WE65|F8WE65_HUMAN" 8 982.4906 - 15800 16073 2 982.487534 492.2526 E3 SUMO-protein ligase RanBP2 OS=Homo sapiens OX=9606 GN=RANBP2 PE=1 SV=2 6.74 3051.6 - 1.05E+06 - - - -3.1217 - 1.478 0.34 - 117.4 1 1 0 -0.0031 10 0 0 0 - - - - - 2.6418 0.9995 221125_WJC_METTL3_EV_vs_WT_F02.16075.16075.2 0.0751 16-Sep K.DVALSVLSK[136.11].D "sp|P30260|CDC27_HUMAN,tr|G5EA36|G5EA36_HUMAN" 2 938.5528 0.63 15802 16075 2 938.553955 470.2837 Cell division cycle protein 27 homolog OS=Homo sapiens OX=9606 GN=CDC27 PE=1 SV=2 5.84 3051.9 - 653469 - - - 1.2338 - 1.9 0.333 - 245 1 2 0 0.0012 9 0 0 0 4.67E+06 7.37E+06 - - - 3.3571 0.9997 221125_WJC_METTL3_EV_vs_WT_F02.16080.16080.2 0.000137 18-Nov K.WYYNAAGFNK[136.11].L "sp|P14927|QCR7_HUMAN,tr|B7Z2R2|B7Z2R2_HUMAN" 2 1240.5757 0.28 15805 16080 2 1240.574646 621.2951 Cytochrome b-c1 complex subunit 7 OS=Homo sapiens OX=9606 GN=UQCRB PE=1 SV=2 8.5 3052.6 - 1.69E+06 - - - -0.8158 - 1.688 0.448 - 326.6 1 2 0 -0.001 10 0 0 0 6.25E+06 2.27E+07 - - - 3.811 0.9998 221125_WJC_METTL3_EV_vs_WT_F02.16081.16081.2 0.000194 20-Dec K.VLC[160.03]ELADLQDK[136.11].E "sp|P17987|TCPA_HUMAN,tr|F5H726|F5H726_HUMAN,tr|F5H136|F5H136_HUMAN,tr|F5GZI8|F5GZI8_HUMAN,tr|E7ERF2|E7ERF2_HUMAN,tr|F5H676|F5H676_HUMAN" 6 1310.6632 0.25 15806 16081 2 1310.661006 656.3389 T-complex protein 1 subunit alpha OS=Homo sapiens OX=9606 GN=TCP1 PE=1 SV=1 4.03 3052.7 - 1.17E+06 - - - -1.6381 - 2.308 0.473 - 571.6 1 2 0 -0.0021 11 0 0 0 1.31E+07 5.18E+07 - - - 4.7965 0.9994 221125_WJC_METTL3_EV_vs_WT_F02.16082.16082.2 0.00014 16-Oct K.LEWVQDNIR[166.11].A sp|O94906|PRP6_HUMAN 1 1181.6068 2.89 15807 16082 2 1181.609787 591.8107 Pre-mRNA-processing factor 6 OS=Homo sapiens OX=9606 GN=PRPF6 PE=1 SV=1 4.37 3052.8 - 2.20E+06 - - - 2.4924 - 2.088 0.419 - 435 1 2 0 0.0029 9 0 0 0 8.82E+07 3.05E+07 - - - 4.2647 0.9998 221125_WJC_METTL3_EV_vs_WT_F02.16083.16083.2 1.31E-06 18-Nov K.WYYNAAGFNK.L "sp|P14927|QCR7_HUMAN,tr|B7Z2R2|B7Z2R2_HUMAN" 2 1232.5615 1.25 15808 16083 2 1232.562054 617.288 Cytochrome b-c1 complex subunit 7 OS=Homo sapiens OX=9606 GN=UQCRB PE=1 SV=2 8.5 3052.8 - 1.70E+06 - - - 0.4835 - 1.938 0.481 - 385.4 1 2 0 0.0006 10 0 0 0 6.99E+07 5.59E+07 - - - 4.4404 1 221125_WJC_METTL3_EV_vs_WT_F02.16084.16084.2 1.76E-07 14/22 R.GLC[160.03]AIAQAESLR[166.11].Y "sp|P23396|RS3_HUMAN,tr|F2Z2S8|F2Z2S8_HUMAN,tr|H0YCJ7|H0YCJ7_HUMAN,tr|H0YF32|H0YF32_HUMAN" 4 1297.6688 0.72 15809 16084 2 1297.668493 649.8417 40S ribosomal protein S3 OS=Homo sapiens OX=9606 GN=RPS3 PE=1 SV=2 5.99 3052.9 - 1.19E+06 - - - -0.2296 - 2.757 0.574 - 807.1 1 2 0 -0.0003 12 0 0 0 4.55E+08 6.27E+08 - - - 5.9489 0.9969 221125_WJC_METTL3_EV_vs_WT_F02.16085.16085.2 0.128 14-Aug K.GLSYLQLK[136.11].N sp|Q69YN4|VIR_HUMAN 1 928.5473 0.13 15810 16085 2 928.548193 465.2809 Protein virilizer homolog OS=Homo sapiens OX=9606 GN=VIRMA PE=1 SV=2 8.59 3053.1 - 1.03E+06 - - - 0.9423 - 1.482 0.193 - 174.6 1 2 0 0.0009 8 0 0 0 5.89E+05 4.65E+06 - - - 1.6527 0.9854 221125_WJC_METTL3_EV_vs_WT_F02.16091.16091.2 1.87 12-Jun K.ALFQLSR.L "sp|Q9H3U1|UN45A_HUMAN,tr|A0A1W2PNX8|A0A1W2PNX8_HUMAN" 2 833.4759 0.76 15816 16091 2 833.475832 417.7452 Protein unc-45 homolog A OS=Homo sapiens OX=9606 GN=UNC45A PE=1 SV=1 9.79 3053.7 - 499417 - - - -0.1272 - 1.221 0.093 - 123.6 1 2 0 -0.0001 7 0 0 0 5.63E+06 7.44E+06 - - - 0.3605 0.9828 221125_WJC_METTL3_EV_vs_WT_F02.16092.16092.2 0.151 16-Oct K.QMLYDYVER[166.11].K sp|Q15054|DPOD3_HUMAN 1 1225.5677 0.58 15817 16092 2 1225.569724 613.7911 DNA polymerase delta subunit 3 OS=Homo sapiens OX=9606 GN=POLD3 PE=1 SV=2 4.37 3053.9 - 454608 - - - 1.6686 - 1.162 0.163 - 136.6 1 2 0 0.002 9 0 0 0 2.77E+06 4.79E+06 - - - 0.6786 0.9996 221125_WJC_METTL3_EV_vs_WT_F02.16097.16097.2 0.0116 14-Aug K.SINEFWNK.F "sp|Q9HBM1|SPC25_HUMAN,tr|C9JW94|C9JW94_HUMAN" 2 1036.4978 3.17 15821 16097 2 1036.498343 519.2562 Kinetochore protein Spc25 OS=Homo sapiens OX=9606 GN=SPC25 PE=1 SV=1 5.72 3054.5 - 931362 - - - 0.5287 - 1.553 0.413 - 180.5 1 2 0 0.0005 8 0 0 0 3.53E+07 1.12E+07 - - - 3.4188 0.9998 221125_WJC_METTL3_EV_vs_WT_F02.16099.16099.2 0.0032 18-Oct R.IVILEYQPSK[136.11].N "sp|Q15393|SF3B3_HUMAN,tr|J3QL37|J3QL37_HUMAN,tr|J3QRB2|J3QRB2_HUMAN" 3 1196.6896 1.13 15823 16099 2 1196.689245 599.3521 Splicing factor 3B subunit 3 OS=Homo sapiens OX=9606 GN=SF3B3 PE=1 SV=4 6 3054.6 - 6.21E+06 - - - -0.3175 - 1.893 0.421 - 316.5 1 2 0 -0.0004 10 0 0 0 8.77E+07 7.74E+07 - - - 3.9317 0.9999 221125_WJC_METTL3_EV_vs_WT_F02.16102.16102.2 0.00154 22-Dec R.GLC[160.03]AIAQAESLR.Y "sp|P23396|RS3_HUMAN,tr|F2Z2S8|F2Z2S8_HUMAN,tr|H0YCJ7|H0YCJ7_HUMAN,tr|H0YF32|H0YF32_HUMAN" 4 1287.6605 0.73 15826 16102 2 1287.660434 644.8375 40S ribosomal protein S3 OS=Homo sapiens OX=9606 GN=RPS3 PE=1 SV=2 5.99 3054.7 - 3.54E+06 - - - -0.0676 - 2.548 0.511 - 541.7 1 2 0 -0.0001 12 0 0 0 4.55E+08 6.27E+08 - - - 5.2762 0.9984 221125_WJC_METTL3_EV_vs_WT_F02.16103.16103.2 1.58 12-Jul K.NFFLTNR.A sp|P17655|CAN2_HUMAN 1 910.4661 1.24 15827 16103 2 910.465589 456.2403 Calpain-2 catalytic subunit OS=Homo sapiens OX=9606 GN=CAPN2 PE=1 SV=6 9.75 3054.7 - 3.07E+06 - - - -0.5623 - 1.565 0.209 - 254.8 1 2 0 -0.0005 7 0 0 0 3.52E+07 2.84E+07 - - - 2.0037 0.9256 221125_WJC_METTL3_EV_vs_WT_F02.16104.16104.2 0.398 14-Jun Q.SIFNIGSR[166.11].G "sp|P43243|MATR3_HUMAN,tr|A8MXP9|A8MXP9_HUMAN,tr|D6R991|D6R991_HUMAN,tr|D6REK4|D6REK4_HUMAN,tr|A0A0R4J2E8|A0A0R4J2E8_HUMAN,tr|D6RCM3|D6RCM3_HUMAN,tr|D6R8Z5|D6R8Z5_HUMAN,tr|D6REM6|D6REM6_HUMAN" 8 902.4849 1.34 15828 16104 2 902.485952 452.2497 Matrin-3 OS=Homo sapiens OX=9606 GN=MATR3 PE=1 SV=2 9.47 3054.8 - 2.33E+06 - - - 1.1258 - 1.461 0.302 - 125.5 1 1 0 0.001 8 0 0 0 4.84E+07 3.60E+07 - - - 2.4147 0.9999 221125_WJC_METTL3_EV_vs_WT_F02.16105.16105.2 4.64E-06 20-Nov K.GYTLVEYETYK.E "sp|Q9Y5S9|RBM8A_HUMAN,tr|A0A0J9YW13|A0A0J9YW13_HUMAN" 2 1364.65 1.62 15829 16105 2 1364.650396 683.3323 RNA-binding protein 8A OS=Homo sapiens OX=9606 GN=RBM8A PE=1 SV=1 4.53 3054.9 - 2.17E+06 - - - 0.2916 - 2.258 0.524 - 524.1 1 2 0 0.0004 11 0 0 0 3.67E+08 2.27E+08 - - - 5.1145 1 221125_WJC_METTL3_EV_vs_WT_F02.16107.16107.2 1.06E-06 20-Dec K.GYTLVEYETYK[136.11].E "sp|Q9Y5S9|RBM8A_HUMAN,tr|A0A0J9YW13|A0A0J9YW13_HUMAN" 2 1372.6642 1.62 15831 16107 2 1372.663505 687.3394 RNA-binding protein 8A OS=Homo sapiens OX=9606 GN=RBM8A PE=1 SV=1 4.53 3055 - 1.92E+06 - - - -0.5049 - 2.458 0.594 - 684.9 1 2 0 -0.0007 11 0 0 0 3.67E+08 2.27E+08 - - - 5.861 0.9997 221125_WJC_METTL3_EV_vs_WT_F02.16108.16108.2 0.00712 18-Dec R.VVVDALSGLK.G "sp|P12532|KCRU_HUMAN,tr|C9JSQ1|C9JSQ1_HUMAN,tr|F8WCN3|F8WCN3_HUMAN" 3 999.5964 1.53 15832 16108 2 999.596364 500.8055 "Creatine kinase U-type, mitochondrial OS=Homo sapiens OX=9606 GN=CKMT1A PE=1 SV=1" 5.81 3055.1 - 1.57E+06 - - - -0.083 - 2.148 0.35 - 402.7 1 2 0 -0.0001 10 0 0 0 3.32E+07 2.17E+07 - - - 3.7601 0.9992 221125_WJC_METTL3_EV_vs_WT_F02.16109.16109.2 0.0161 14-Aug R.GLDIPSIK.T "sp|Q86XP3|DDX42_HUMAN,tr|A0A0A0MSJ0|A0A0A0MSJ0_HUMAN" 2 841.4909 -1 15833 16109 2 841.490296 421.7527 ATP-dependent RNA helicase DDX42 OS=Homo sapiens OX=9606 GN=DDX42 PE=1 SV=1 5.84 3055.2 - 1.54E+06 - - - -0.7404 - 1.739 0.262 - 215 1 2 0 -0.0006 8 0 0 0 0.00E+00 0.00E+00 - - - 2.6447 0.9996 221125_WJC_METTL3_EV_vs_WT_F02.16110.16110.2 0.0404 14-Sep R.DGAWGAFR.H "sp|P49327|FAS_HUMAN,tr|A0A0U1RQF0|A0A0U1RQF0_HUMAN" 2 878.4035 0.6 15834 16110 2 878.40297 440.209 Fatty acid synthase OS=Homo sapiens OX=9606 GN=FASN PE=1 SV=3 5.84 3055.3 - 1.44E+06 - - - -0.6045 - 1.637 0.37 - 426.7 1 2 0 -0.0005 8 0 0 0 2.10E+07 3.50E+07 - - - 3.2601 0.9872 221125_WJC_METTL3_EV_vs_WT_F02.16111.16111.2 8.14E-05 20-Oct N.VITSDQPILLR.L "sp|Q9BY77|PDIP3_HUMAN,tr|F6VRR5|F6VRR5_HUMAN" 2 1253.7343 1.39 15835 16111 2 1253.734866 627.8744 Polymerase delta-interacting protein 3 OS=Homo sapiens OX=9606 GN=POLDIP3 PE=1 SV=2 5.81 3055.4 - 1.20E+06 - - - 0.4219 - 1.764 0.472 - 350.3 1 1 0 0.0005 11 0 0 0 1.97E+07 1.42E+07 - - - 4.0625 0.9997 221125_WJC_METTL3_EV_vs_WT_F02.16112.16112.2 3.84E-07 18-Oct K.DVAIDMMDSR.T "sp|Q13190|STX5_HUMAN,tr|H7C3X5|H7C3X5_HUMAN" 2 1151.4951 1.25 15836 16112 2 1151.495202 576.7548 Syntaxin-5 OS=Homo sapiens OX=9606 GN=STX5 PE=1 SV=2 3.93 3055.5 - 1.75E+06 - - - 0.0938 - 2.095 0.343 - 394.4 1 2 0 0.0001 10 0 0 0 1.23E+07 9.87E+06 - - - 3.6387 0.9997 221125_WJC_METTL3_EV_vs_WT_F02.16113.16113.2 1.45E-05 14/20 K.VLC[160.03]ELADLQDK.E "sp|P17987|TCPA_HUMAN,tr|F5H726|F5H726_HUMAN,tr|F5H136|F5H136_HUMAN,tr|F5GZI8|F5GZI8_HUMAN,tr|E7ERF2|E7ERF2_HUMAN,tr|F5H676|F5H676_HUMAN" 6 1302.649 0.25 15837 16113 2 1302.646492 652.3318 T-complex protein 1 subunit alpha OS=Homo sapiens OX=9606 GN=TCP1 PE=1 SV=1 4.03 3055.6 - 1.04E+06 - - - -1.8892 - 2.471 0.445 - 787.7 1 2 0 -0.0025 11 0 0 0 1.31E+07 5.17E+07 - - - 4.7742 0.9997 221125_WJC_METTL3_EV_vs_WT_F02.16115.16115.2 0.00552 18-Oct R.VVVDALSGLK[136.11].G "sp|P12532|KCRU_HUMAN,tr|C9JSQ1|C9JSQ1_HUMAN,tr|F8WCN3|F8WCN3_HUMAN" 3 1007.6106 1.53 15839 16115 2 1007.609165 504.8126 "Creatine kinase U-type, mitochondrial OS=Homo sapiens OX=9606 GN=CKMT1A PE=1 SV=1" 5.81 3055.8 - 887552 - - - -1.4708 - 2.062 0.411 - 302.2 1 2 0 -0.0015 10 0 0 0 3.32E+07 2.17E+07 - - - 4.0962 0.9968 221125_WJC_METTL3_EV_vs_WT_F02.16116.16116.2 0.0123 18-Aug K.DNPLDPVLAK.V sp|Q96AG4|LRC59_HUMAN 1 1080.5815 0.76 15840 16116 2 1080.584062 541.298 Leucine-rich repeat-containing protein 59 OS=Homo sapiens OX=9606 GN=LRRC59 PE=1 SV=1 4.21 3055.8 - 1.28E+06 - - - 2.3478 - 1.223 0.364 - 140.6 1 2 0 0.0025 10 0 0 0 1.18E+08 1.56E+08 - - - 2.2906 0.9993 221125_WJC_METTL3_EV_vs_WT_F02.16118.16118.2 0.0246 12-Jul K.NFFLTNR[166.11].A sp|P17655|CAN2_HUMAN 1 920.4744 1.23 15841 16118 2 920.474567 461.2445 Calpain-2 catalytic subunit OS=Homo sapiens OX=9606 GN=CAPN2 PE=1 SV=6 9.75 3056.1 - 2.20E+06 - - - 0.2129 - 1.437 0.342 - 245.4 1 2 0 0.0002 7 0 0 0 3.66E+07 2.98E+07 - - - 2.7157 0.988 221125_WJC_METTL3_EV_vs_WT_F02.16119.16119.2 0.463 14-Jul K.DLTELVQR.R "sp|Q9BYC5|FUT8_HUMAN,tr|G3XAD2|G3XAD2_HUMAN,tr|A0A669KAW1|A0A669KAW1_HUMAN" 3 972.524 0.91 15842 16119 2 972.521426 487.2693 "Alpha-(1,6)-fucosyltransferase OS=Homo sapiens OX=9606 GN=FUT8 PE=1 SV=2" 4.37 3056.1 - 466378 - - - -2.657 - 1.359 0.19 - 139.9 1 2 0 -0.0026 8 0 0 0 2.72E+06 3.00E+06 - - - 1.3687 1 221125_WJC_METTL3_EV_vs_WT_F02.16121.16121.3 0.000836 13/44 R.GLC[160.03]AIAQAESLR[166.11].Y "sp|P23396|RS3_HUMAN,tr|F2Z2S8|F2Z2S8_HUMAN,tr|H0YCJ7|H0YCJ7_HUMAN,tr|H0YF32|H0YF32_HUMAN" 4 1297.6688 0.69 15844 16121 3 1297.669033 433.5635 40S ribosomal protein S3 OS=Homo sapiens OX=9606 GN=RPS3 PE=1 SV=2 5.99 3056.3 - 1.92E+06 - - - 0.1865 - 2.635 0.493 - 369.1 1 2 0 0.0002 12 0 0 0 5.89E+07 8.51E+07 - - - 6.722 0.9922 221125_WJC_METTL3_EV_vs_WT_F02.16122.16122.2 6.60E-06 13/26 S.VSVAGGTQPLLLAK.E "sp|Q86UP3|ZFHX4_HUMAN,tr|A0A494BZV7|A0A494BZV7_HUMAN,tr|E5RI93|E5RI93_HUMAN,tr|E7EVZ1|E7EVZ1_HUMAN" 4 1352.8028 1.58 15845 16122 2 1352.802368 677.4087 Zinc finger homeobox protein 4 OS=Homo sapiens OX=9606 GN=ZFHX4 PE=1 SV=1 8.72 3056.4 - 1.06E+06 - - - -0.2831 - 2.183 0.504 - 571.1 1 1 0 -0.0004 14 0 0 0 1.62E+07 1.03E+07 - - - 4.7226 0.9998 221125_WJC_METTL3_EV_vs_WT_F02.16123.16123.3 0.00142 Dec-44 R.GLC[160.03]AIAQAESLR.Y "sp|P23396|RS3_HUMAN,tr|F2Z2S8|F2Z2S8_HUMAN,tr|H0YCJ7|H0YCJ7_HUMAN,tr|H0YF32|H0YF32_HUMAN" 4 1287.6605 0.69 15846 16123 3 1287.659831 430.2275 40S ribosomal protein S3 OS=Homo sapiens OX=9606 GN=RPS3 PE=1 SV=2 5.99 3056.5 - 1.03E+06 - - - -0.5359 - 2.398 0.327 - 259.1 1 2 0 -0.0007 12 0 0 0 5.88E+07 8.50E+07 - - - 4.6099 0.9988 221125_WJC_METTL3_EV_vs_WT_F02.16132.16132.2 0.000128 16-Sep R.MWQSMC[160.03]PLR.Q "sp|O75643|U520_HUMAN,tr|A0A494C1A5|A0A494C1A5_HUMAN" 2 1207.53 1.16 15853 16132 2 1207.52525 604.7723 U5 small nuclear ribonucleoprotein 200 kDa helicase OS=Homo sapiens OX=9606 GN=SNRNP200 PE=1 SV=2 8 3057.6 - 1.18E+06 - - - -3.9668 - 1.861 0.524 - 403.1 1 2 0 -0.0048 9 0 0 0 1.72E+07 1.48E+07 - - - 4.7067 0.9996 221125_WJC_METTL3_EV_vs_WT_F02.16133.16133.2 0.000823 16-Aug K.EAWDLGVC[160.03]R[166.11].D sp|P19474|RO52_HUMAN 1 1114.5105 1.62 15854 16133 2 1114.509426 558.2625 E3 ubiquitin-protein ligase TRIM21 OS=Homo sapiens OX=9606 GN=TRIM21 PE=1 SV=1 4.37 3057.7 - 1.34E+06 - - - -0.9628 - 1.655 0.394 - 255.1 1 2 0 -0.0011 9 0 0 0 2.79E+07 1.72E+07 - - - 3.4083 1 221125_WJC_METTL3_EV_vs_WT_F02.16135.16135.3 2.86E-06 17/48 R.LPLAQVSAHPWVR[166.11].A "sp|Q96GD4|AURKB_HUMAN,tr|J3KT86|J3KT86_HUMAN" 2 1482.8335 1.07 15856 16135 3 1482.829596 495.2851 Aurora kinase B OS=Homo sapiens OX=9606 GN=AURKB PE=1 SV=3 9.76 3057.9 - 818520 - - - -2.6247 - 3.365 0.499 - 531.6 1 2 0 -0.0039 13 0 0 0 1.70E+07 1.60E+07 - - - 7.3922 0.9994 221125_WJC_METTL3_EV_vs_WT_F02.16136.16136.2 0.00458 18-Sep R.LLENMTEVVR[166.11].K "sp|Q6P996|PDXD1_HUMAN,tr|H3BND4|H3BND4_HUMAN" 2 1212.6412 1.29 15857 16136 2 1212.642015 607.3279 Pyridoxal-dependent decarboxylase domain-containing protein 1 OS=Homo sapiens OX=9606 GN=PDXDC1 PE=1 SV=2 4.53 3058.1 - 1.02E+06 - - - 0.6894 - 2.202 0.241 - 218.5 1 2 0 0.0008 10 0 0 0 1.96E+07 1.51E+07 - - - 3.0241 0.9821 221125_WJC_METTL3_EV_vs_WT_F02.16138.16138.2 0.464 12-Jul R.AVTIFIR[166.11].G "sp|P48643|TCPE_HUMAN,sp|Q6ZVL6|K154L_HUMAN,tr|E9PCA1|E9PCA1_HUMAN,tr|B7ZAR1|B7ZAR1_HUMAN,tr|E7ENZ3|E7ENZ3_HUMAN,tr|H0YDE5|H0YDE5_HUMAN,tr|A0A590UJI0|A0A590UJI0_HUMAN,tr|A0A5F9UK30|A0A5F9UK30_HUMAN" 8 828.5097 0.57 15859 16138 2 828.509694 415.2621 T-complex protein 1 subunit epsilon OS=Homo sapiens OX=9606 GN=CCT5 PE=1 SV=1 9.79 3058.3 - 540521 - - - 0 - 1.439 0.023 - 211.9 2 2 0 0 7 0 0 0 1.17E+07 2.04E+07 - - - 0.2296 0.9991 221125_WJC_METTL3_EV_vs_WT_F02.16142.16142.2 0.0207 16-Sep R.VLDELTLAR.A "sp|Q04695|K1C17_HUMAN,sp|P02533|K1C14_HUMAN,sp|P08727|K1C19_HUMAN,sp|P08779|K1C16_HUMAN,sp|P19012|K1C15_HUMAN,tr|K7EPJ9|K7EPJ9_HUMAN,tr|C9JM50|C9JM50_HUMAN,tr|C9JTG5|C9JTG5_HUMAN,tr|F5GWP8|F5GWP8_HUMAN,tr|K7EMS3|K7EMS3_HUMAN,tr|A8MT21|A8MT21_HUMAN" 11 1028.5866 30.04 15861 16142 2 1028.588722 515.3006 "Keratin, type I cytoskeletal 17 OS=Homo sapiens OX=9606 GN=KRT17 PE=1 SV=2" 4.37 3058.9 - 2.78E+06 - - - 2.0533 - 2.011 0.313 - 285.9 1 2 0 0.0021 9 0 0 0 2.12E+09 7.05E+07 - - - 3.3733 0.9983 221125_WJC_METTL3_EV_vs_WT_F02.16148.16148.2 0.117 14-Oct K.QWLQEIDR[166.11].Y "sp|Q9H0U4|RAB1B_HUMAN,sp|P62820|RAB1A_HUMAN,sp|Q92928|RAB1C_HUMAN,tr|E9PLD0|E9PLD0_HUMAN,tr|E7END7|E7END7_HUMAN" 5 1096.5541 1.14 15867 16148 2 1096.552422 549.2843 Ras-related protein Rab-1B OS=Homo sapiens OX=9606 GN=RAB1B PE=1 SV=1 4.37 3059.4 - 1.29E+06 - - - -1.5102 - 1.828 0.193 - 384.2 1 2 0 -0.0017 8 0 0 0 2.77E+08 2.44E+08 - - - 2.2853 0.9998 221125_WJC_METTL3_EV_vs_WT_F02.16149.16149.2 1.12E-05 22-Oct R.AVFDETYPDPVR.V "sp|P49588|SYAC_HUMAN,tr|A0A6Q8PGR9|A0A6Q8PGR9_HUMAN,tr|A0A6Q8PFY2|A0A6Q8PFY2_HUMAN,tr|A0A6Q8PFK3|A0A6Q8PFK3_HUMAN,tr|H3BPK7|H3BPK7_HUMAN,tr|A0A6Q8PHJ2|A0A6Q8PHJ2_HUMAN,tr|A0A6Q8PGB5|A0A6Q8PGB5_HUMAN,tr|A0A6Q8PGE8|A0A6Q8PGE8_HUMAN,tr|A0A6Q8PF33|A0A6Q8PF33_HUMAN,tr|A0A6Q8PGN5|A0A6Q8PGN5_HUMAN" 10 1407.667 1.71 15868 16149 2 1407.6647 704.8408 "Alanine--tRNA ligase, cytoplasmic OS=Homo sapiens OX=9606 GN=AARS1 PE=1 SV=2" 4.03 3059.5 - 968701 - - - -1.6659 - 2.152 0.58 - 154.2 1 2 0 -0.0023 12 0 0 0 1.55E+07 9.05E+06 - - - 5.3407 0.9996 221125_WJC_METTL3_EV_vs_WT_F02.16151.16151.2 0.000726 12-Aug K.NFFVNYR[166.11].R "sp|Q9UKL0|RCOR1_HUMAN,sp|Q9P2K3|RCOR3_HUMAN,tr|H0YF22|H0YF22_HUMAN" 3 968.4744 1.67 15870 16151 2 968.473864 485.2445 REST corepressor 1 OS=Homo sapiens OX=9606 GN=RCOR1 PE=1 SV=2 8.75 3059.7 - 686245 - - - -0.5235 - 1.591 0.383 - 272.8 1 2 0 -0.0005 7 0 0 0 4.93E+07 2.95E+07 - - - 3.341 0.9996 221125_WJC_METTL3_EV_vs_WT_F02.16155.16155.2 0.00206 18-Oct K.EVMLVGIGDK.L sp|P36542|ATPG_HUMAN 1 1059.5634 1.6 15872 16155 2 1059.563927 530.789 "ATP synthase subunit gamma, mitochondrial OS=Homo sapiens OX=9606 GN=ATP5F1C PE=1 SV=1" 4.37 3060.2 - 4.92E+06 - - - 0.4672 - 1.837 0.344 - 459.8 1 2 0 0.0005 10 0 0 0 2.01E+08 1.25E+08 - - - 3.2791 0.9996 221125_WJC_METTL3_EV_vs_WT_F02.16157.16157.2 1.95E-05 20-Nov R.ATLYVTAIEDR[166.11].Q "sp|Q99873|ANM1_HUMAN,tr|E9PQ98|E9PQ98_HUMAN,tr|E9PKG1|E9PKG1_HUMAN,tr|E9PNR9|E9PNR9_HUMAN,tr|H0YDE4|H0YDE4_HUMAN,tr|E9PIX6|E9PIX6_HUMAN" 6 1260.6589 1.93 15874 16157 2 1260.662175 631.3367 Protein arginine N-methyltransferase 1 OS=Homo sapiens OX=9606 GN=PRMT1 PE=1 SV=3 4.37 3060.4 - 3.07E+06 - - - 2.5685 - 2.289 0.503 - 577.1 1 2 0 0.0032 11 0 0 0 5.75E+08 2.98E+08 - - - 4.9954 0.9995 221125_WJC_METTL3_EV_vs_WT_F02.16162.16162.2 0.000417 16-Sep K.ADSLLAVVK[136.11].R "sp|Q14151|SAFB2_HUMAN,sp|Q15424|SAFB1_HUMAN" 2 922.5579 2.13 15879 16162 2 922.559363 462.2862 Scaffold attachment factor B2 OS=Homo sapiens OX=9606 GN=SAFB2 PE=1 SV=1 5.88 3061 - 669316 - - - 1.6042 - 1.895 0.392 - 290.6 1 2 0 0.0015 9 0 0 0 2.83E+08 1.33E+08 - - - 3.7851 0.9821 221125_WJC_METTL3_EV_vs_WT_F02.16163.16163.2 1.17 12-Jul R.AVTIFIR.G "sp|P48643|TCPE_HUMAN,sp|Q6ZVL6|K154L_HUMAN,tr|E9PCA1|E9PCA1_HUMAN,tr|B7ZAR1|B7ZAR1_HUMAN,tr|E7ENZ3|E7ENZ3_HUMAN,tr|H0YDE5|H0YDE5_HUMAN,tr|A0A590UJI0|A0A590UJI0_HUMAN,tr|A0A5F9UK30|A0A5F9UK30_HUMAN" 8 818.5014 0.57 15880 16163 2 818.499995 410.258 T-complex protein 1 subunit epsilon OS=Homo sapiens OX=9606 GN=CCT5 PE=1 SV=1 9.79 3061.1 - 582267 - - - -1.7459 - 1.368 0.08 - 217.2 1 2 0 -0.0014 7 0 0 0 1.17E+07 2.04E+07 - - - 0.6243 0.9997 221125_WJC_METTL3_EV_vs_WT_F02.16168.16168.2 0.000138 12-Jul K.NFFVNYR.R "sp|Q9UKL0|RCOR1_HUMAN,sp|Q9P2K3|RCOR3_HUMAN,tr|H0YF22|H0YF22_HUMAN" 3 958.4661 1.72 15883 16168 2 958.466305 480.2403 REST corepressor 1 OS=Homo sapiens OX=9606 GN=RCOR1 PE=1 SV=2 8.75 3061.7 - 2.46E+06 - - - 0.2128 - 1.452 0.444 - 173.6 1 2 0 0.0002 7 0 0 0 5.12E+07 2.99E+07 - - - 3.502 0.9821 221125_WJC_METTL3_EV_vs_WT_F02.16169.16169.2 0.000468 18-Nov N.ALESYAFNMK[136.11].S "sp|P0DMV8|HS71A_HUMAN,sp|P34931|HS71L_HUMAN,sp|P0DMV9|HS71B_HUMAN,tr|Q53FA3|Q53FA3_HUMAN,tr|V9GZ37|V9GZ37_HUMAN,tr|A0A0G2JIW1|A0A0G2JIW1_HUMAN" 6 1180.5678 0.07 15884 16169 2 1180.566283 591.2912 Heat shock 70 kDa protein 1A OS=Homo sapiens OX=9606 GN=HSPA1A PE=1 SV=1 6.05 3061.8 - 1.41E+06 - - - -1.2816 - 2.025 0.398 - 330.8 1 1 0 -0.0015 10 0 0 0 1.48E+06 2.09E+07 - - - 3.9496 1 221125_WJC_METTL3_EV_vs_WT_F02.16171.16171.2 0.000111 14/28 K.VGEVIVTK[136.11]DDAMLLK[136.11].G "sp|P10809|CH60_HUMAN,tr|A0A7I2V2X6|A0A7I2V2X6_HUMAN,tr|A0A7I2YQK6|A0A7I2YQK6_HUMAN,tr|A0A7I2V599|A0A7I2V599_HUMAN" 4 1645.9295 1.19 15886 16171 2 1645.931126 823.972 "60 kDa heat shock protein, mitochondrial OS=Homo sapiens OX=9606 GN=HSPD1 PE=1 SV=2" 4.56 3062.1 - 345099 - - - 0.9606 - 3.1 0.528 - 593 1 2 1 0.0016 15 0 0 0 2.44E+07 2.05E+07 - - - 5.7219 0.9995 221125_WJC_METTL3_EV_vs_WT_F02.16176.16176.2 0.00639 16-Aug K.LTLISEDIK[136.11].S "sp|P18031|PTN1_HUMAN,tr|B4DSN5|B4DSN5_HUMAN" 2 1038.6052 4.11 15888 16176 2 1038.605589 520.3099 Tyrosine-protein phosphatase non-receptor type 1 OS=Homo sapiens OX=9606 GN=PTPN1 PE=1 SV=1 4.37 3062.7 - 1.58E+06 - - - 0.3485 - 1.636 0.346 - 144.4 1 2 0 0.0004 9 0 0 0 4.25E+08 1.03E+08 - - - 3.0206 0.9984 221125_WJC_METTL3_EV_vs_WT_F02.16177.16177.2 0.158 24-Nov K.AGLATAGPGLLPR.K "sp|O15417|TNC18_HUMAN,tr|H9KVB4|H9KVB4_HUMAN" 2 1192.6928 3.1 15889 16177 2 1192.690313 597.3537 Trinucleotide repeat-containing gene 18 protein OS=Homo sapiens OX=9606 GN=TNRC18 PE=1 SV=3 9.79 3062.8 - 932227 - - - -2.0911 - 2.19 0.223 - 287.1 1 2 0 -0.0025 13 0 0 0 3.69E+07 1.19E+07 - - - 2.6992 0.9997 221125_WJC_METTL3_EV_vs_WT_F02.16179.16179.2 0.00105 20-Oct R.IGVPSATEIIK[136.11].A sp|Q9NR30|DDX21_HUMAN 1 1134.674 1.13 15891 16179 2 1134.675804 568.3443 Nucleolar RNA helicase 2 OS=Homo sapiens OX=9606 GN=DDX21 PE=1 SV=5 6 3063.1 - 887603 - - - 1.6119 - 2.13 0.415 - 254.9 1 2 0 0.0018 11 0 0 0 1.87E+08 1.66E+08 - - - 4.1511 0.9999 221125_WJC_METTL3_EV_vs_WT_F02.16182.16182.2 1.01E-05 20-Dec R.ATLYVTAIEDR.Q "sp|Q99873|ANM1_HUMAN,tr|E9PQ98|E9PQ98_HUMAN,tr|E9PKG1|E9PKG1_HUMAN,tr|E9PNR9|E9PNR9_HUMAN,tr|H0YDE4|H0YDE4_HUMAN,tr|E9PIX6|E9PIX6_HUMAN" 6 1250.6507 1.93 15892 16182 2 1250.650392 626.3326 Protein arginine N-methyltransferase 1 OS=Homo sapiens OX=9606 GN=PRMT1 PE=1 SV=3 4.37 3063.4 - 1.94E+07 - - - -0.2199 - 2.525 0.53 - 719.5 1 2 0 -0.0003 11 0 0 0 5.75E+08 2.98E+08 - - - 5.4612 0.999 221125_WJC_METTL3_EV_vs_WT_F02.16183.16183.2 0.619 14-Sep R.LIEILSEK[136.11].A "sp|Q9P2E9|RRBP1_HUMAN,tr|A0A087WVV2|A0A087WVV2_HUMAN,tr|F8W7S5|F8W7S5_HUMAN" 3 951.5732 1.24 15893 16183 2 951.572594 476.7939 Ribosome-binding protein 1 OS=Homo sapiens OX=9606 GN=RRBP1 PE=1 SV=5 4.53 3063.5 - 2.76E+06 - - - -0.6358 - 1.674 0.245 - 239.7 1 2 0 -0.0006 8 0 0 0 7.86E+07 6.34E+07 - - - 2.4042 0.9975 221125_WJC_METTL3_EV_vs_WT_F02.16184.16184.2 0.0717 12-Jul K.FTDLFEK[136.11].M "sp|Q8WUM4|PDC6I_HUMAN,sp|Q9HCP0|KC1G1_HUMAN,tr|Q8IXA3|Q8IXA3_HUMAN,tr|A0A0U1RR31|A0A0U1RR31_HUMAN,tr|U3KQB3|U3KQB3_HUMAN,tr|A0A0U1RQT7|A0A0U1RQT7_HUMAN,tr|U3KQA5|U3KQA5_HUMAN,tr|A0A0U1RQY7|A0A0U1RQY7_HUMAN,tr|A0A0U1RQG9|A0A0U1RQG9_HUMAN,tr|A0A0U1RQK6|A0A0U1RQK6_HUMAN" 10 906.4578 0.7 15894 16184 2 906.457512 454.2362 Programmed cell death 6-interacting protein OS=Homo sapiens OX=9606 GN=PDCD6IP PE=1 SV=1 4.37 3063.6 - 1.45E+06 - - - -0.3552 - 1.579 0.152 - 122.2 1 2 0 -0.0003 7 0 0 0 2.17E+07 3.08E+07 - - - 1.6109 0.9934 221125_WJC_METTL3_EV_vs_WT_F02.16185.16185.2 0.852 12-Jun K.EQLPIFK[136.11].A "sp|Q00059|TFAM_HUMAN,tr|H7BYN3|H7BYN3_HUMAN" 2 881.5102 1.19 15895 16185 2 881.509271 441.7624 "Transcription factor A, mitochondrial OS=Homo sapiens OX=9606 GN=TFAM PE=1 SV=1" 6.1 3063.7 - 1.31E+06 - - - -1.0584 - 1.35 0.144 - 138.8 1 2 0 -0.0009 7 0 0 0 1.69E+08 1.42E+08 - - - 1.0552 0.9986 221125_WJC_METTL3_EV_vs_WT_F02.16186.16186.2 0.0099 20-Sep R.IGVPSATEIIK.A sp|Q9NR30|DDX21_HUMAN 1 1126.6598 1.12 15896 16186 2 1126.660241 564.3372 Nucleolar RNA helicase 2 OS=Homo sapiens OX=9606 GN=DDX21 PE=1 SV=5 6 3063.8 - 933021 - - - 0.4136 - 1.575 0.251 - 166.3 1 2 0 0.0005 11 0 0 0 1.85E+08 1.65E+08 - - - 2.1236 0.9835 221125_WJC_METTL3_EV_vs_WT_F02.16187.16187.2 12.9 12-Jun K.FDLMYAK.R "sp|Q9NY65|TBA8_HUMAN,sp|Q6PEY2|TBA3E_HUMAN,sp|P0DPH7|TBA3C_HUMAN,sp|Q71U36|TBA1A_HUMAN,sp|P0DPH8|TBA3D_HUMAN,sp|A6NHL2|TBAL3_HUMAN,sp|P68366|TBA4A_HUMAN,sp|P68363|TBA1B_HUMAN,sp|Q9BQE3|TBA1C_HUMAN,tr|F5H5D3|F5H5D3_HUMAN,tr|C9J2C0|C9J2C0_HUMAN,tr|V9GZ17|V9GZ17_HUMAN,tr|A0A7P0T945|A0A7P0T945_HUMAN" 13 886.4259 0.55 15897 16187 2 886.425353 444.2202 Tubulin alpha-8 chain OS=Homo sapiens OX=9606 GN=TUBA8 PE=1 SV=1 5.83 3063.9 - 602485 - - - -0.59 - 1.12 0.124 - 101.3 1 2 0 -0.0005 7 0 0 0 1.70E+07 3.10E+07 - - - 0.3158 0.9999 221125_WJC_METTL3_EV_vs_WT_F02.16188.16188.3 0.00011 Nov-36 K.WLPELVEHAK.N "sp|Q02252|MMSA_HUMAN,tr|G3V4Z4|G3V4Z4_HUMAN" 2 1220.6554 1.54 15898 16188 3 1220.654632 407.8924 "Methylmalonate-semialdehyde dehydrogenase [acylating], mitochondrial OS=Homo sapiens OX=9606 GN=ALDH6A1 PE=1 SV=2" 5.4 3064.1 - 372831 - - - -0.5956 - 2.186 0.422 - 199.1 1 2 0 -0.0007 10 0 0 0 5.92E+06 3.84E+06 - - - 5.5287 0.9971 221125_WJC_METTL3_EV_vs_WT_F02.16189.16189.2 0.00364 24-Oct K.AILAGAQPIEEMR.H sp|Q8WWK9|CKAP2_HUMAN 1 1397.7337 0.81 15899 16189 2 1397.739001 699.8741 Cytoskeleton-associated protein 2 OS=Homo sapiens OX=9606 GN=CKAP2 PE=1 SV=1 4.53 3064.2 - 334596 - - - 3.8033 - 2.131 0.326 - 310.1 1 2 0 0.0053 13 0 0 0 7.68E+06 9.51E+06 - - - 3.389 0.9941 221125_WJC_METTL3_EV_vs_WT_F02.16191.16191.2 0.0951 12-Aug R.FQLEELR.K "sp|Q8WWM7|ATX2L_HUMAN,tr|H3BUF6|H3BUF6_HUMAN" 2 933.492 1.41 15900 16191 2 933.491251 467.7533 Ataxin-2-like protein OS=Homo sapiens OX=9606 GN=ATXN2L PE=1 SV=2 4.53 3064.4 - 2.61E+06 - - - -0.7831 - 1.512 0.096 - 230.4 1 2 0 -0.0007 7 0 0 0 6.04E+07 4.29E+07 - - - 1.0598 0.9971 221125_WJC_METTL3_EV_vs_WT_F02.16193.16193.2 0.0456 12-Sep K.FTDLFEK.M "sp|Q8WUM4|PDC6I_HUMAN,sp|Q9HCP0|KC1G1_HUMAN,tr|Q8IXA3|Q8IXA3_HUMAN,tr|A0A0U1RR31|A0A0U1RR31_HUMAN,tr|U3KQB3|U3KQB3_HUMAN,tr|A0A0U1RQT7|A0A0U1RQT7_HUMAN,tr|U3KQA5|U3KQA5_HUMAN,tr|A0A0U1RQY7|A0A0U1RQY7_HUMAN,tr|A0A0U1RQG9|A0A0U1RQG9_HUMAN,tr|A0A0U1RQK6|A0A0U1RQK6_HUMAN" 10 898.4436 0.7 15901 16193 2 898.444258 450.2291 Programmed cell death 6-interacting protein OS=Homo sapiens OX=9606 GN=PDCD6IP PE=1 SV=1 4.37 3064.6 - 1.17E+06 - - - 0.6945 - 1.696 0.122 - 201.6 1 2 0 0.0006 7 0 0 0 2.17E+07 3.08E+07 - - - 1.6158 0.9894 221125_WJC_METTL3_EV_vs_WT_F02.16195.16195.2 0.0262 12-Jul K.FDLMYAK[136.11].R "sp|Q9NY65|TBA8_HUMAN,sp|Q6PEY2|TBA3E_HUMAN,sp|P0DPH7|TBA3C_HUMAN,sp|Q71U36|TBA1A_HUMAN,sp|P0DPH8|TBA3D_HUMAN,sp|A6NHL2|TBAL3_HUMAN,sp|P68366|TBA4A_HUMAN,sp|P68363|TBA1B_HUMAN,sp|Q9BQE3|TBA1C_HUMAN,tr|F5H5D3|F5H5D3_HUMAN,tr|C9J2C0|C9J2C0_HUMAN,tr|V9GZ17|V9GZ17_HUMAN,tr|A0A7P0T945|A0A7P0T945_HUMAN" 13 894.4401 0.56 15903 16195 2 894.437186 448.2273 Tubulin alpha-8 chain OS=Homo sapiens OX=9606 GN=TUBA8 PE=1 SV=1 5.83 3064.8 - 1.76E+06 - - - -3.2311 - 1.494 0.199 - 144.1 1 2 0 -0.0029 7 0 0 0 1.70E+07 3.04E+07 - - - 1.7819 0.996 221125_WJC_METTL3_EV_vs_WT_F02.16196.16196.2 0.967 12-Jul K.EQLPIFK.A "sp|Q00059|TFAM_HUMAN,tr|H7BYN3|H7BYN3_HUMAN" 2 873.496 1.14 15904 16196 2 873.495327 437.7553 "Transcription factor A, mitochondrial OS=Homo sapiens OX=9606 GN=TFAM PE=1 SV=1" 6.1 3064.9 - 1.41E+06 - - - -0.775 - 1.416 0.162 - 188.7 1 2 0 -0.0007 7 0 0 0 1.62E+08 1.42E+08 - - - 1.3395 0.9717 221125_WJC_METTL3_EV_vs_WT_F02.16197.16197.2 1.93 20-Jul K.LYGSIFTGASK.F sp|Q63HK5|TSH3_HUMAN 1 1142.5972 1.24 15905 16197 2 1142.596771 572.3059 Teashirt homolog 3 OS=Homo sapiens OX=9606 GN=TSHZ3 PE=1 SV=2 8.59 3065 - 810043 - - - -0.3536 - 1.137 0.074 - 72.6 1 2 0 -0.0004 11 0 0 0 8.10E+06 6.55E+06 - - - -0.0652 0.9997 221125_WJC_METTL3_EV_vs_WT_F02.16198.16198.2 0.000601 20-Sep M.VPPVQVSPLIK[136.11].L sp|P56385|ATP5I_HUMAN 1 1183.742 1.97 15906 16198 2 1183.741463 592.8783 "ATP synthase subunit e, mitochondrial OS=Homo sapiens OX=9606 GN=ATP5ME PE=1 SV=2" 8.72 3065.1 - 754063 - - - -0.4494 - 1.573 0.443 - 146 1 2 0 -0.0005 11 0 0 0 6.70E+07 3.40E+07 - - - 3.5383 0.9986 221125_WJC_METTL3_EV_vs_WT_F02.16199.16199.3 0.011 Sep-40 R.ATLYVTAIEDR.Q "sp|Q99873|ANM1_HUMAN,tr|E9PQ98|E9PQ98_HUMAN,tr|E9PKG1|E9PKG1_HUMAN,tr|E9PNR9|E9PNR9_HUMAN,tr|H0YDE4|H0YDE4_HUMAN,tr|E9PIX6|E9PIX6_HUMAN" 6 1250.6507 1.51 15907 16199 3 1250.649616 417.8908 Protein arginine N-methyltransferase 1 OS=Homo sapiens OX=9606 GN=PRMT1 PE=1 SV=3 4.37 3065.2 - 396840 - - - -0.8404 - 1.787 0.258 - 175.5 1 2 0 -0.0011 11 0 0 0 4.01E+06 2.66E+06 - - - 3.0654 0.9999 221125_WJC_METTL3_EV_vs_WT_F02.16202.16202.2 7.66E-06 13/20 R.IFGGVLESDAR.S "sp|O00165|HAX1_HUMAN,tr|E9PIQ7|E9PIQ7_HUMAN" 2 1162.5982 1.33 15909 16202 2 1162.598169 582.3064 HCLS1-associated protein X-1 OS=Homo sapiens OX=9606 GN=HAX1 PE=1 SV=2 4.37 3065.6 - 1.59E+07 - - - -0.0593 - 2.537 0.461 - 605 1 2 0 -0.0001 11 0 0 0 3.37E+08 2.54E+08 - - - 4.9645 0.9999 221125_WJC_METTL3_EV_vs_WT_F02.16204.16204.2 8.59E-05 20-Dec R.IFGGVLESDAR[166.11].S "sp|O00165|HAX1_HUMAN,tr|E9PIQ7|E9PIQ7_HUMAN" 2 1172.6065 1.35 15910 16204 2 1172.605863 587.3105 HCLS1-associated protein X-1 OS=Homo sapiens OX=9606 GN=HAX1 PE=1 SV=2 4.37 3065.8 - 7.39E+06 - - - -0.5501 - 2.187 0.467 - 360.6 1 2 0 -0.0006 11 0 0 0 3.36E+08 2.50E+08 - - - 4.607 0.9991 221125_WJC_METTL3_EV_vs_WT_F02.16205.16205.2 0.766 16-Aug R.GIALWGGEK.F "sp|P55884|EIF3B_HUMAN,tr|C9JQN7|C9JQN7_HUMAN" 2 929.4971 1 15911 16205 2 929.496623 465.7558 Eukaryotic translation initiation factor 3 subunit B OS=Homo sapiens OX=9606 GN=EIF3B PE=1 SV=3 6 3065.8 - 3.64E+06 - - - -0.4777 - 1.707 0.26 - 204.7 1 2 0 -0.0004 9 0 0 0 8.03E+07 8.04E+07 - - - 2.5082 0.9992 221125_WJC_METTL3_EV_vs_WT_F02.16206.16206.2 0.000356 14-Jul R.QLAEDFLK[136.11].D "sp|P17844|DDX5_HUMAN,tr|A0A7I2V5F5|A0A7I2V5F5_HUMAN,tr|J3KRZ1|J3KRZ1_HUMAN,tr|J3QSF1|J3QSF1_HUMAN,tr|A0A7I2V507|A0A7I2V507_HUMAN,tr|J3KTA4|J3KTA4_HUMAN,tr|A0A0G2JLI4|A0A0G2JLI4_HUMAN,tr|A0A7I2V2S0|A0A7I2V2S0_HUMAN" 8 970.5215 1.73 15912 16206 2 970.519343 486.268 Probable ATP-dependent RNA helicase DDX5 OS=Homo sapiens OX=9606 GN=DDX5 PE=1 SV=1 4.37 3065.9 - 3.68E+06 - - - -2.2194 - 1.57 0.421 - 186.3 1 2 0 -0.0022 8 0 0 0 2.86E+08 1.65E+08 - - - 3.5103 0.9986 221125_WJC_METTL3_EV_vs_WT_F02.16207.16207.2 1.16 14-Sep K.DSGSFLLR[166.11].N sp|Q8NDZ4|DIK2A_HUMAN 1 903.469 1.47 15913 16207 2 903.467653 452.7418 Divergent protein kinase domain 2A OS=Homo sapiens OX=9606 GN=DIPK2A PE=1 SV=1 5.84 3066 - 1.42E+06 - - - -1.4367 - 1.743 0.233 - 436.4 1 2 0 -0.0013 8 0 0 0 3.84E+07 2.62E+07 - - - 2.4372 0.9999 221125_WJC_METTL3_EV_vs_WT_F02.16208.16208.2 3.78E-05 20-Dec K.IVPNVLLEQGK[136.11].A "sp|O75390|CISY_HUMAN,tr|H0YIC4|H0YIC4_HUMAN,tr|B4DJV2|B4DJV2_HUMAN,tr|A0A0C4DGI3|A0A0C4DGI3_HUMAN" 4 1216.7271 1.06 15914 16208 2 1216.726733 609.3708 "Citrate synthase, mitochondrial OS=Homo sapiens OX=9606 GN=CS PE=1 SV=2" 6 3066.1 - 985622 - - - -0.2794 - 2.259 0.58 - 509.4 1 2 0 -0.0003 11 0 0 0 4.01E+07 3.78E+07 - - - 5.5293 0.9999 221125_WJC_METTL3_EV_vs_WT_F02.16209.16209.2 7.52E-06 15/24 K.LATQLTGPVMPVR[166.11].N sp|P26373|RL13_HUMAN 1 1391.7834 1.11 15915 16209 2 1391.78234 696.899 60S ribosomal protein L13 OS=Homo sapiens OX=9606 GN=RPL13 PE=1 SV=4 9.75 3066.2 - 594065 - - - -0.7803 - 2.704 0.491 - 817.9 1 2 0 -0.0011 13 0 0 0 2.17E+08 1.96E+08 - - - 5.2202 0.9998 221125_WJC_METTL3_EV_vs_WT_F02.16210.16210.2 0.00146 17/24 K.AILAGAQPIEEMR[166.11].H sp|Q8WWK9|CKAP2_HUMAN 1 1407.742 0.81 15916 16210 2 1407.742475 704.8783 Cytoskeleton-associated protein 2 OS=Homo sapiens OX=9606 GN=CKAP2 PE=1 SV=1 4.53 3066.4 - 572755 - - - 0.3694 - 2.134 0.397 - 302.9 1 2 0 0.0005 13 0 0 0 7.68E+06 9.51E+06 - - - 3.9185 0.9992 221125_WJC_METTL3_EV_vs_WT_F02.16211.16211.2 0.00119 24-Oct R.VLSNTEDLPLVTK.M sp|P0DP57|SLUR2_HUMAN 1 1427.7872 999 15917 16211 2 1427.787219 714.9009 Secreted Ly-6\uPAR domain-containing protein 2 OS=Homo sapiens OX=9606 GN=SLURP2 PE=1 SV=1 4.37 3066.5 - 483540 - - - 0.0406 - 1.518 0.336 - 78.6 1 2 0 0.0001 13 0 0 0 1.59E+07 0.00E+00 - - - 2.5939 0.9997 221125_WJC_METTL3_EV_vs_WT_F02.16217.16217.3 0.385 19/56 K.VGEVIVTK[136.11]DDAMLLK[136.11].G "sp|P10809|CH60_HUMAN,tr|A0A7I2V2X6|A0A7I2V2X6_HUMAN,tr|A0A7I2YQK6|A0A7I2YQK6_HUMAN,tr|A0A7I2V599|A0A7I2V599_HUMAN" 4 1645.9295 1.36 15921 16217 3 1645.927974 549.6505 "60 kDa heat shock protein, mitochondrial OS=Homo sapiens OX=9606 GN=HSPD1 PE=1 SV=2" 4.56 3067.3 - 1.87E+07 - - - -0.9545 - 2.912 0.395 - 509.6 1 2 1 -0.0016 15 0 0 0 3.97E+08 2.93E+08 - - - 5.7324 0.9999 221125_WJC_METTL3_EV_vs_WT_F02.16218.16218.2 1.55E-07 14/20 K.C[160.03]VLNEGMPIYR[166.11].R sp|P31689|DNJA1_HUMAN 1 1360.6507 0.3 15922 16218 2 1360.649755 681.3326 DnaJ homolog subfamily A member 1 OS=Homo sapiens OX=9606 GN=DNAJA1 PE=1 SV=2 5.99 3067.3 - 5.97E+06 - - - -0.6931 - 2.292 0.583 - 576.6 1 2 0 -0.0009 11 0 0 0 3.77E+07 1.26E+08 - - - 5.5905 0.9998 221125_WJC_METTL3_EV_vs_WT_F02.16219.16219.2 7.87E-06 22-Oct R.VVGAMQLYSVDR[166.11].K "sp|Q00610|CLH1_HUMAN,sp|P53675|CLH2_HUMAN,tr|A0A087WVQ6|A0A087WVQ6_HUMAN,tr|A0A087WX41|A0A087WX41_HUMAN" 4 1346.6892 0.59 15923 16219 2 1346.688039 674.3519 Clathrin heavy chain 1 OS=Homo sapiens OX=9606 GN=CLTC PE=1 SV=5 5.81 3067.4 - 3.84E+06 - - - -0.8554 - 2.106 0.496 - 338.3 1 2 0 -0.0012 12 0 0 0 4.72E+07 8.05E+07 - - - 4.6638 0.9998 221125_WJC_METTL3_EV_vs_WT_F02.16220.16220.2 0.0171 13/24 K.LATQLTGPVMPVR.N sp|P26373|RL13_HUMAN 1 1381.7752 1.11 15924 16220 2 1381.774002 691.8949 60S ribosomal protein L13 OS=Homo sapiens OX=9606 GN=RPL13 PE=1 SV=4 9.75 3067.5 - 1.64E+06 - - - -0.8352 - 2.627 0.336 - 517.6 1 2 0 -0.0012 13 0 0 0 2.17E+08 1.96E+08 - - - 4.0012 1 221125_WJC_METTL3_EV_vs_WT_F02.16221.16221.3 2.22E-06 16/40 K.IIFSEHLPLSK.L "sp|Q9Y2L1|RRP44_HUMAN,tr|F2Z2C0|F2Z2C0_HUMAN,tr|G3V1J5|G3V1J5_HUMAN" 3 1282.7285 1.45 15925 16221 3 1282.728405 428.5835 Exosome complex exonuclease RRP44 OS=Homo sapiens OX=9606 GN=DIS3 PE=1 SV=2 6.75 3067.6 - 1.34E+06 - - - -0.0928 - 2.742 0.501 - 473.4 1 2 0 -0.0001 11 0 0 0 9.80E+07 6.76E+07 - - - 6.9911 0.9992 221125_WJC_METTL3_EV_vs_WT_F02.16222.16222.3 0.00417 Oct-36 R.LVVLGIR[166.11]PIR[166.11].L sp|Q92900|RENT1_HUMAN 1 1154.7766 0.02 15926 16222 3 1154.775831 385.9328 Regulator of nonsense transcripts 1 OS=Homo sapiens OX=9606 GN=UPF1 PE=1 SV=2 12 3067.7 - 1.34E+06 - - - -0.6988 - 1.495 0.339 - 153.7 1 2 0 -0.0008 10 0 0 0 1.14E+06 4.81E+07 - - - 3.4937 0.9086 221125_WJC_METTL3_EV_vs_WT_F02.16223.16223.2 0.423 20-Oct K.LEAGDYADLVK.A sp|Q14008|CKAP5_HUMAN 1 1192.5976 0.93 15927 16223 2 1192.601911 597.3061 Cytoskeleton-associated protein 5 OS=Homo sapiens OX=9606 GN=CKAP5 PE=1 SV=3 4.03 3067.8 - 1.12E+06 - - - 3.6408 - 1.738 0.002 - 197.7 2 2 0 0.0043 11 0 0 0 2.26E+07 2.45E+07 - - - 0.4152 0.9996 221125_WJC_METTL3_EV_vs_WT_F02.16224.16224.2 4.57E-07 20-Nov K.IVPNVLLEQGK.A "sp|O75390|CISY_HUMAN,tr|H0YIC4|H0YIC4_HUMAN,tr|B4DJV2|B4DJV2_HUMAN,tr|A0A0C4DGI3|A0A0C4DGI3_HUMAN" 4 1208.7129 1.06 15928 16224 2 1208.712245 605.3637 "Citrate synthase, mitochondrial OS=Homo sapiens OX=9606 GN=CS PE=1 SV=2" 6 3067.9 - 1.08E+06 - - - -0.5196 - 2.08 0.314 - 462.1 1 2 0 -0.0006 11 0 0 0 4.01E+07 3.78E+07 - - - 3.3412 0.9987 221125_WJC_METTL3_EV_vs_WT_F02.16229.16229.2 0.106 14-Jul R.LIEILSEK.A "sp|Q9P2E9|RRBP1_HUMAN,tr|A0A087WVV2|A0A087WVV2_HUMAN,tr|F8W7S5|F8W7S5_HUMAN" 3 943.559 1.23 15932 16229 2 943.558432 472.7868 Ribosome-binding protein 1 OS=Homo sapiens OX=9606 GN=RRBP1 PE=1 SV=5 4.53 3068.5 - 3.29E+06 - - - -0.6009 - 1.538 0.254 - 124 1 2 0 -0.0006 8 0 0 0 7.86E+07 6.41E+07 - - - 2.2152 0.9999 221125_WJC_METTL3_EV_vs_WT_F02.16231.16231.3 4.10E-05 19/56 K.VGEVIVTKDDAMLLK.G "sp|P10809|CH60_HUMAN,tr|A0A7I2V2X6|A0A7I2V2X6_HUMAN,tr|A0A7I2YQK6|A0A7I2YQK6_HUMAN,tr|A0A7I2V599|A0A7I2V599_HUMAN" 4 1629.9011 1.36 15933 16231 3 1629.900811 544.3077 "60 kDa heat shock protein, mitochondrial OS=Homo sapiens OX=9606 GN=HSPD1 PE=1 SV=2" 4.56 3068.7 - 3.44E+07 - - - -0.2049 - 3.127 0.469 - 596 1 2 1 -0.0003 15 0 0 0 3.97E+08 2.92E+08 - - - 6.7437 0.9998 221125_WJC_METTL3_EV_vs_WT_F02.16232.16232.2 9.82E-05 16-Aug R.AAPFSLEYR.V "sp|Q15181|IPYR_HUMAN,tr|Q5SQT6|Q5SQT6_HUMAN" 2 1052.5291 0.42 15934 16232 2 1052.528239 527.2718 Inorganic pyrophosphatase OS=Homo sapiens OX=9606 GN=PPA1 PE=1 SV=2 6.05 3068.8 - 2.19E+06 - - - -0.8133 - 1.84 0.447 - 312.1 1 2 0 -0.0009 9 0 0 0 6.77E+07 1.63E+08 - - - 4.1064 0.9993 221125_WJC_METTL3_EV_vs_WT_F02.16233.16233.2 0.0013 18-Sep R.INEILSNALK.R "sp|P52272|HNRPM_HUMAN,tr|M0R019|M0R019_HUMAN,tr|A0A087X0X3|A0A087X0X3_HUMAN" 3 1113.6394 1.77 15935 16233 2 1113.639929 557.827 Heterogeneous nuclear ribonucleoprotein M OS=Homo sapiens OX=9606 GN=HNRNPM PE=1 SV=3 6 3068.8 - 2.42E+06 - - - 0.4984 - 2.063 0.231 - 216.6 1 2 0 0.0006 10 0 0 0 2.28E+09 1.29E+09 - - - 2.7683 0.9973 221125_WJC_METTL3_EV_vs_WT_F02.16234.16234.2 0.332 14-Jul K.DSGSFLLR.N sp|Q8NDZ4|DIK2A_HUMAN 1 893.4607 1.56 15936 16234 2 893.46066 447.7376 Divergent protein kinase domain 2A OS=Homo sapiens OX=9606 GN=DIPK2A PE=1 SV=1 5.84 3068.9 - 2.22E+06 - - - -0.0235 - 1.572 0.156 - 172.5 1 2 0 0 8 0 0 0 4.08E+07 2.62E+07 - - - 1.5575 1 221125_WJC_METTL3_EV_vs_WT_F02.16235.16235.2 1.50E-07 18/28 K.VGEVIVTKDDAMLLK.G "sp|P10809|CH60_HUMAN,tr|A0A7I2V2X6|A0A7I2V2X6_HUMAN,tr|A0A7I2YQK6|A0A7I2YQK6_HUMAN,tr|A0A7I2V599|A0A7I2V599_HUMAN" 4 1629.9011 1.19 15937 16235 2 1629.901649 815.9578 "60 kDa heat shock protein, mitochondrial OS=Homo sapiens OX=9606 GN=HSPD1 PE=1 SV=2" 4.56 3069 - 2.14E+06 - - - 0.3092 - 3.646 0.619 - 840 1 2 1 0.0005 15 0 0 0 2.44E+07 2.05E+07 - - - 6.7932 0.9794 221125_WJC_METTL3_EV_vs_WT_F02.16236.16236.3 0.0568 Oct-40 K.IIFSEHLPLSK[136.11].L "sp|Q9Y2L1|RRP44_HUMAN,tr|F2Z2C0|F2Z2C0_HUMAN,tr|G3V1J5|G3V1J5_HUMAN" 3 1290.7427 1.45 15938 16236 3 1290.744806 431.2549 Exosome complex exonuclease RRP44 OS=Homo sapiens OX=9606 GN=DIS3 PE=1 SV=2 6.75 3069.1 - 1.67E+06 - - - 1.613 - 1.467 0.179 - 87.2 1 2 0 0.0021 11 0 0 0 9.80E+07 6.76E+07 - - - 1.6238 0.9997 221125_WJC_METTL3_EV_vs_WT_F02.16237.16237.2 0.00125 20-Dec K.ILTTIEDLDQK[136.11].K "sp|O95347|SMC2_HUMAN,tr|A0A0C4DGE5|A0A0C4DGE5_HUMAN" 2 1295.7064 0.5 15939 16237 2 1295.707594 648.8605 Structural maintenance of chromosomes protein 2 OS=Homo sapiens OX=9606 GN=SMC2 PE=1 SV=2 4.03 3069.2 - 939360 - - - 0.923 - 2.306 0.366 - 499.7 1 2 0 0.0012 11 0 0 0 4.61E+06 9.20E+06 - - - 4.0042 1 221125_WJC_METTL3_EV_vs_WT_F02.16241.16241.2 1.54E-06 15/26 V.GEVIVTKDDAMLLK.G "sp|P10809|CH60_HUMAN,tr|A0A7I2V2X6|A0A7I2V2X6_HUMAN,tr|A0A7I2YQK6|A0A7I2YQK6_HUMAN,tr|A0A7I2V599|A0A7I2V599_HUMAN" 4 1530.8327 2.44 15943 16241 2 1530.83416 766.4236 "60 kDa heat shock protein, mitochondrial OS=Homo sapiens OX=9606 GN=HSPD1 PE=1 SV=2" 4.56 3069.7 - 259774 - - - 0.9335 - 3.028 0.548 - 410 1 1 1 0.0014 14 0 0 0 3.75E+06 1.54E+06 - - - 5.8683 0.9994 221125_WJC_METTL3_EV_vs_WT_F02.16246.16246.2 0.0847 18-Dec R.INEILSNALK[136.11].R "sp|P52272|HNRPM_HUMAN,tr|M0R019|M0R019_HUMAN,tr|A0A087X0X3|A0A087X0X3_HUMAN" 3 1121.6536 1.77 15946 16246 2 1121.654994 561.8341 Heterogeneous nuclear ribonucleoprotein M OS=Homo sapiens OX=9606 GN=HNRNPM PE=1 SV=3 6 3070.2 - 5.91E+06 - - - 1.266 - 2.313 0.265 - 429.1 1 2 0 0.0014 10 0 0 0 2.28E+09 1.29E+09 - - - 3.3385 0.9999 221125_WJC_METTL3_EV_vs_WT_F02.16247.16247.2 0.229 18-Nov K.TLAAEMQELR[166.11].V "sp|Q8N163|CCAR2_HUMAN,tr|H0YB24|H0YB24_HUMAN,tr|G3V119|G3V119_HUMAN" 3 1170.5942 1.5 15947 16247 2 1170.594434 586.3044 Cell cycle and apoptosis regulator protein 2 OS=Homo sapiens OX=9606 GN=CCAR2 PE=1 SV=2 4.53 3070.2 - 2.32E+06 - - - 0.176 - 2.111 0.491 - 392.7 1 2 0 0.0002 10 0 0 0 3.08E+08 2.06E+08 - - - 4.753 0.9879 221125_WJC_METTL3_EV_vs_WT_F02.16248.16248.2 0.197 12-May R.EFDVSFR[166.11].S sp|Q9NUD5|ZCHC3_HUMAN 1 908.4268 0.91 15948 16248 2 908.42545 455.2207 Zinc finger CCHC domain-containing protein 3 OS=Homo sapiens OX=9606 GN=ZCCHC3 PE=1 SV=2 4.37 3070.3 - 1.58E+06 - - - -1.4332 - 1.154 0.171 - 113.3 1 2 0 -0.0013 7 0 0 0 2.66E+07 2.91E+07 - - - 0.7574 0.9992 221125_WJC_METTL3_EV_vs_WT_F02.16250.16250.2 0.00815 18-Aug K.AYAALAALEK.L sp|Q12906|ILF3_HUMAN 1 1019.5651 0.38 15950 16250 2 1019.566375 510.7898 Interleukin enhancer-binding factor 3 OS=Homo sapiens OX=9606 GN=ILF3 PE=1 SV=3 6.05 3070.4 - 1.38E+06 - - - 1.2044 - 1.594 0.352 - 179.7 1 2 0 0.0012 10 0 0 0 3.45E+08 8.97E+08 - - - 2.9419 0.7781 221125_WJC_METTL3_EV_vs_WT_F02.16252.16252.2 0.0326 22-Sep R.LGELILTSESSR.Y "sp|Q14197|ICT1_HUMAN,tr|J3KS15|J3KS15_HUMAN" 2 1303.6983 0.14 15952 16252 2 1303.688422 652.8564 "Peptidyl-tRNA hydrolase ICT1, mitochondrial OS=Homo sapiens OX=9606 GN=MRPL58 PE=1 SV=1" 4.53 3070.6 - 719563 - - - -7.6122 - 1.846 0.126 - 236.2 1 2 0 -0.0099 12 0 0 0 1.98E+06 1.42E+07 - - - 1.5815 0.9997 221125_WJC_METTL3_EV_vs_WT_F02.16254.16254.2 0.00196 14/22 R.LGELILTSESSR[166.11].Y "sp|Q14197|ICT1_HUMAN,tr|J3KS15|J3KS15_HUMAN" 2 1313.7066 0.11 15954 16254 2 1313.704414 657.8606 "Peptidyl-tRNA hydrolase ICT1, mitochondrial OS=Homo sapiens OX=9606 GN=MRPL58 PE=1 SV=1" 4.53 3070.9 - 385946 - - - -1.6762 - 2.769 0.336 - 886.9 1 2 0 -0.0022 12 0 0 0 1.85E+06 1.69E+07 - - - 4.2018 0.9999 221125_WJC_METTL3_EV_vs_WT_F02.16258.16258.2 2.59E-10 14/22 K.FAQALGLTEAVK.V "sp|P78347|GTF2I_HUMAN,tr|A0A494C1K3|A0A494C1K3_HUMAN" 2 1246.6921 1.47 15956 16258 2 1246.692673 624.3533 General transcription factor II-I OS=Homo sapiens OX=9606 GN=GTF2I PE=1 SV=2 6 3071.3 - 2.30E+07 - - - 0.4291 - 2.812 0.459 - 694.2 1 2 0 0.0005 12 0 0 0 1.59E+09 1.08E+09 - - - 5.1514 0.9999 221125_WJC_METTL3_EV_vs_WT_F02.16259.16259.2 1.64E-08 13/22 K.FAQALGLTEAVK[136.11].V "sp|P78347|GTF2I_HUMAN,tr|A0A494C1K3|A0A494C1K3_HUMAN" 2 1254.7063 1.47 15957 16259 2 1254.706657 628.3604 General transcription factor II-I OS=Homo sapiens OX=9606 GN=GTF2I PE=1 SV=2 6 3071.4 - 1.72E+07 - - - 0.2542 - 2.527 0.548 - 607.1 1 2 0 0.0003 12 0 0 0 1.59E+09 1.08E+09 - - - 5.5276 0.9997 221125_WJC_METTL3_EV_vs_WT_F02.16260.16260.2 0.00183 18-Nov K.TLAAEMQELR.V "sp|Q8N163|CCAR2_HUMAN,tr|H0YB24|H0YB24_HUMAN,tr|G3V119|G3V119_HUMAN" 3 1160.586 1.47 15958 16260 2 1160.58684 581.3003 Cell cycle and apoptosis regulator protein 2 OS=Homo sapiens OX=9606 GN=CCAR2 PE=1 SV=2 4.53 3071.4 - 3.22E+06 - - - 0.76 - 2.212 0.372 - 344.2 1 2 0 0.0009 10 0 0 0 3.09E+08 2.09E+08 - - - 4.0043 0.821 221125_WJC_METTL3_EV_vs_WT_F02.16261.16261.2 0.113 14-Jun K.NSHLINVL.M "sp|O15372|EIF3H_HUMAN,tr|B3KS98|B3KS98_HUMAN,tr|A0A087WZK9|A0A087WZK9_HUMAN,tr|E5RGU4|E5RGU4_HUMAN,tr|E5RJT0|E5RJT0_HUMAN" 5 908.508 - 15959 16261 2 908.508155 455.2613 Eukaryotic translation initiation factor 3 subunit H OS=Homo sapiens OX=9606 GN=EIF3H PE=1 SV=1 6.74 3071.5 - 2.58E+06 - - - 0.208 - 1.173 0.248 - 117.3 1 1 0 0.0002 8 0 0 0 - - - - - 1.3539 0.9925 221125_WJC_METTL3_EV_vs_WT_F02.16262.16262.2 9.32E-05 20-Dec K.ILTTIEDLDQK.K "sp|O95347|SMC2_HUMAN,tr|A0A0C4DGE5|A0A0C4DGE5_HUMAN" 2 1287.6922 0.5 15960 16262 2 1287.700139 644.8534 Structural maintenance of chromosomes protein 2 OS=Homo sapiens OX=9606 GN=SMC2 PE=1 SV=2 4.03 3071.6 - 961001 - - - 6.1668 - 2.232 0.416 - 375.6 1 2 0 0.0079 11 0 0 0 4.61E+06 9.20E+06 - - - 4.2831 0.9998 221125_WJC_METTL3_EV_vs_WT_F02.16265.16265.2 0.000113 26-Nov R.LSYVGNNFGTGALK[136.11].C "sp|Q9GZS1|RPA49_HUMAN,tr|E7EX70|E7EX70_HUMAN" 2 1447.7551 0.54 15963 16265 2 1447.754566 724.8848 DNA-directed RNA polymerase I subunit RPA49 OS=Homo sapiens OX=9606 GN=POLR1E PE=1 SV=3 8.59 3071.9 - 206709 - - - -0.3543 - 1.985 0.492 - 179.7 1 2 0 -0.0005 14 0 0 0 2.87E+06 5.27E+06 - - - 4.3953 0.9995 221125_WJC_METTL3_EV_vs_WT_F02.16270.16270.2 0.00112 14-Aug K.SVFEAFGK[136.11].L "sp|Q9UHX1|PUF60_HUMAN,tr|A0A0J9YYL3|A0A0J9YYL3_HUMAN,tr|A0A0J9YWM1|A0A0J9YWM1_HUMAN,tr|H0YEM1|H0YEM1_HUMAN,tr|A0A0J9YVR6|A0A0J9YVR6_HUMAN,tr|A0A0J9YXX5|A0A0J9YXX5_HUMAN,tr|A0A0J9YXJ8|A0A0J9YXJ8_HUMAN,tr|E9PQ56|E9PQ56_HUMAN,tr|H0YCP8|H0YCP8_HUMAN,tr|A0A0J9YVP6|A0A0J9YVP6_HUMAN" 10 891.4582 0.98 15966 16270 2 891.458327 446.7364 Poly(U)-binding-splicing factor PUF60 OS=Homo sapiens OX=9606 GN=PUF60 PE=1 SV=1 5.72 3072.4 - 4.25E+06 - - - 0.1772 - 1.296 0.449 - 190.6 1 2 0 0.0002 8 0 0 0 1.14E+08 1.16E+08 - - - 3.1392 0.9998 221125_WJC_METTL3_EV_vs_WT_F02.16272.16272.2 0.0158 20-Sep R.FQELLASPAYR.A sp|Q9NSI2|SLX9_HUMAN 1 1293.6717 1.44 15968 16272 2 1293.672387 647.8431 Ribosome biogenesis protein SLX9 homolog OS=Homo sapiens OX=9606 GN=SLX9 PE=1 SV=2 6 3072.5 - 2.60E+06 - - - 0.5024 - 2.055 0.397 - 315.7 1 2 0 0.0006 11 0 0 0 7.24E+08 5.01E+08 - - - 3.9216 0.9999 221125_WJC_METTL3_EV_vs_WT_F02.16274.16274.3 0.000104 Nov-44 K.FAQALGLTEAVK.V "sp|P78347|GTF2I_HUMAN,tr|A0A494C1K3|A0A494C1K3_HUMAN" 2 1246.6921 1.34 15970 16274 3 1246.69039 416.5713 General transcription factor II-I OS=Homo sapiens OX=9606 GN=GTF2I PE=1 SV=2 6 3072.7 - 1.19E+06 - - - -1.4021 - 2.273 0.409 - 152.5 1 2 0 -0.0017 12 0 0 0 2.90E+07 2.16E+07 - - - 5.3754 0.9988 221125_WJC_METTL3_EV_vs_WT_F02.16275.16275.2 0.0184 20-Sep M.VPPVQVSPLIK.L sp|P56385|ATP5I_HUMAN 1 1175.7278 1.98 15971 16275 2 1175.726059 588.8712 "ATP synthase subunit e, mitochondrial OS=Homo sapiens OX=9606 GN=ATP5ME PE=1 SV=2" 8.72 3072.8 - 942176 - - - -1.4765 - 1.619 0.309 - 181.5 1 2 0 -0.0017 11 0 0 0 6.65E+07 3.37E+07 - - - 2.6261 0.9993 221125_WJC_METTL3_EV_vs_WT_F02.16276.16276.2 0.0247 18-Oct K.FAAQELIEVK[136.11].R "sp|Q86U44|MTA70_HUMAN,tr|F5H6D8|F5H6D8_HUMAN,tr|H0YFV6|H0YFV6_HUMAN,tr|B4DTN4|B4DTN4_HUMAN" 4 1154.6427 0.13 15972 16276 2 1154.640896 578.3286 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 4.53 3072.9 - 765518 - - - -1.5407 - 1.724 0.354 - 247.9 1 2 0 -0.0018 10 0 0 0 1.06E+06 8.16E+06 - - - 3.1754 0.9978 221125_WJC_METTL3_EV_vs_WT_F02.16281.16281.2 0.393 12-Jul R.FDILPSR.S "sp|Q08188|TGM3_HUMAN,tr|A0A494C0J7|A0A494C0J7_HUMAN" 2 846.46 39.68 15977 16281 2 846.460536 424.2373 Protein-glutamine gamma-glutamyltransferase E OS=Homo sapiens OX=9606 GN=TGM3 PE=1 SV=4 5.84 3073.6 - 384932 - - - 0.6888 - 1.398 0.233 - 171.7 1 2 0 0.0006 7 0 0 0 5.48E+07 1.38E+06 - - - 1.8234 0.994 221125_WJC_METTL3_EV_vs_WT_F02.16285.16285.2 0.0214 14-Jul K.SVFEAFGK.L "sp|Q9UHX1|PUF60_HUMAN,tr|A0A0J9YYL3|A0A0J9YYL3_HUMAN,tr|A0A0J9YWM1|A0A0J9YWM1_HUMAN,tr|H0YEM1|H0YEM1_HUMAN,tr|A0A0J9YVR6|A0A0J9YVR6_HUMAN,tr|A0A0J9YXX5|A0A0J9YXX5_HUMAN,tr|A0A0J9YXJ8|A0A0J9YXJ8_HUMAN,tr|E9PQ56|E9PQ56_HUMAN,tr|H0YCP8|H0YCP8_HUMAN,tr|A0A0J9YVP6|A0A0J9YVP6_HUMAN" 10 883.444 0.99 15979 16285 2 883.442874 442.7293 Poly(U)-binding-splicing factor PUF60 OS=Homo sapiens OX=9606 GN=PUF60 PE=1 SV=1 5.72 3074.1 - 6.25E+06 - - - -1.2395 - 1.111 0.247 - 153.1 1 2 0 -0.0011 8 0 0 0 1.14E+08 1.15E+08 - - - 1.1825 0.9985 221125_WJC_METTL3_EV_vs_WT_F02.16287.16287.2 0.559 14-Jul R.LYELDGLR.E "sp|Q9Y5K5|UCHL5_HUMAN,tr|H0Y4E0|H0Y4E0_HUMAN,tr|Q5LJA9|Q5LJA9_HUMAN,tr|H0Y6Y4|H0Y6Y4_HUMAN,tr|Q5LJB0|Q5LJB0_HUMAN,tr|Q5LJA5|Q5LJA5_HUMAN" 6 977.5182 2.43 15981 16287 2 977.517384 489.7664 Ubiquitin carboxyl-terminal hydrolase isozyme L5 OS=Homo sapiens OX=9606 GN=UCHL5 PE=1 SV=3 4.37 3074.3 - 2.21E+06 - - - -0.8307 - 1.555 0.236 - 181.9 1 2 0 -0.0008 8 0 0 0 4.47E+07 1.84E+07 - - - 2.1153 0.9993 221125_WJC_METTL3_EV_vs_WT_F02.16288.16288.2 0.0512 14-Aug R.LYELDGLR[166.11].E "sp|Q9Y5K5|UCHL5_HUMAN,tr|H0Y4E0|H0Y4E0_HUMAN,tr|Q5LJA9|Q5LJA9_HUMAN,tr|H0Y6Y4|H0Y6Y4_HUMAN,tr|Q5LJB0|Q5LJB0_HUMAN,tr|Q5LJA5|Q5LJA5_HUMAN" 6 987.5265 2.34 15982 16288 2 987.526578 494.7705 Ubiquitin carboxyl-terminal hydrolase isozyme L5 OS=Homo sapiens OX=9606 GN=UCHL5 PE=1 SV=3 4.37 3074.4 - 1.35E+06 - - - 0.1134 - 1.669 0.295 - 219 1 2 0 0.0001 8 0 0 0 4.29E+07 1.84E+07 - - - 2.7647 0.9734 221125_WJC_METTL3_EV_vs_WT_F02.16289.16289.2 0.0193 18-Oct R.C[160.03]VVILPDSVR[166.11].N "sp|P35520|CBS_HUMAN,tr|H7C2H4|H7C2H4_HUMAN" 2 1166.6357 0.49 15983 16289 2 1167.636284 584.3251 Cystathionine beta-synthase OS=Homo sapiens OX=9606 GN=CBS PE=1 SV=2 5.83 3074.4 - 959226 - - - 857.6671 - 2.099 0.416 - 384.7 1 2 0 1.0006 10 0 0 0 1.18E+07 2.39E+07 - - - 3.869 0.9867 221125_WJC_METTL3_EV_vs_WT_F02.16293.16293.2 1.85 12-Jun R.DLEWVER[166.11].L "sp|Q99848|EBP2_HUMAN,tr|H7C2Q8|H7C2Q8_HUMAN" 2 955.4639 1.15 15987 16293 2 955.463633 478.7392 Probable rRNA-processing protein EBP2 OS=Homo sapiens OX=9606 GN=EBNA1BP2 PE=1 SV=2 4.14 3074.9 - 778938 - - - -0.2439 - 1.214 0.104 - 145.2 1 2 0 -0.0002 7 0 0 0 1.50E+07 1.30E+07 - - - 0.4235 0.9969 221125_WJC_METTL3_EV_vs_WT_F02.16294.16294.2 0.201 12-Jul R.DLEWVER.L "sp|Q99848|EBP2_HUMAN,tr|H7C2Q8|H7C2Q8_HUMAN" 2 945.4556 1.15 15988 16294 2 945.454614 473.7351 Probable rRNA-processing protein EBP2 OS=Homo sapiens OX=9606 GN=EBNA1BP2 PE=1 SV=2 4.14 3075 - 686667 - - - -1.0387 - 1.49 0.177 - 216.1 1 2 0 -0.001 7 0 0 0 1.50E+07 1.30E+07 - - - 1.6116 0.9995 221125_WJC_METTL3_EV_vs_WT_F02.16296.16296.2 0.000116 18-Sep K.ITALDEFATK.L "sp|Q13813|SPTN1_HUMAN,tr|A0A0D9SF54|A0A0D9SF54_HUMAN,tr|A0A0D9SGF6|A0A0D9SGF6_HUMAN" 3 1107.5812 1.24 15989 16296 2 1107.578675 554.7979 "Spectrin alpha chain, non-erythrocytic 1 OS=Homo sapiens OX=9606 GN=SPTAN1 PE=1 SV=3" 4.37 3075.2 - 5.36E+06 - - - -2.2716 - 1.956 0.425 - 185.5 1 2 0 -0.0025 10 0 0 0 8.41E+07 6.76E+07 - - - 4.052 0.9995 221125_WJC_METTL3_EV_vs_WT_F02.16298.16298.2 0.000581 18-Oct K.AYAALAALEK[136.11].L sp|Q12906|ILF3_HUMAN 1 1027.5793 0.7 15990 16298 2 1027.577888 514.7969 Interleukin enhancer-binding factor 3 OS=Homo sapiens OX=9606 GN=ILF3 PE=1 SV=3 6.05 3075.5 - 1.99E+07 - - - -1.4198 - 1.958 0.344 - 317.5 1 2 0 -0.0015 10 0 0 0 3.15E+08 4.51E+08 - - - 3.4569 0.9998 221125_WJC_METTL3_EV_vs_WT_F02.16301.16301.3 5.89E-06 13/44 K.FAQALGLTEAVK[136.11].V "sp|P78347|GTF2I_HUMAN,tr|A0A494C1K3|A0A494C1K3_HUMAN" 2 1254.7063 1.34 15993 16301 3 1254.702942 419.2427 General transcription factor II-I OS=Homo sapiens OX=9606 GN=GTF2I PE=1 SV=2 6 3075.7 - 1.31E+06 - - - -2.7066 - 2.145 0.435 - 217.9 1 2 0 -0.0034 12 0 0 0 2.90E+07 2.16E+07 - - - 5.5042 0.9969 221125_WJC_METTL3_EV_vs_WT_F02.16303.16303.2 0.00664 16-Jul R.AFSYYGPLR.T "sp|Q16629|SRSF7_HUMAN,tr|C9JAB2|C9JAB2_HUMAN,tr|A0A0B4J1Z1|A0A0B4J1Z1_HUMAN" 3 1072.5342 1.23 15995 16303 2 1072.532245 537.2744 Serine\arginine-rich splicing factor 7 OS=Homo sapiens OX=9606 GN=SRSF7 PE=1 SV=1 8.63 3075.9 - 1.46E+06 - - - -1.8051 - 1.448 0.247 - 106.5 1 2 0 -0.0019 9 0 0 0 1.72E+08 1.40E+08 - - - 1.9357 0.9917 221125_WJC_METTL3_EV_vs_WT_F02.16306.16306.2 0.0186 12-Jun K.DMYNIIR.L sp|P53701|CCHL_HUMAN 1 923.4535 1.17 15998 16306 2 923.451683 462.734 Holocytochrome c-type synthase OS=Homo sapiens OX=9606 GN=HCCS PE=1 SV=1 5.84 3076.2 - 570558 - - - -1.9546 - 1.298 0.19 - 173.1 1 2 0 -0.0018 7 0 0 0 1.33E+07 1.14E+07 - - - 1.2702 0.9974 221125_WJC_METTL3_EV_vs_WT_F02.16311.16311.2 0.0589 18-Nov K.ALELDSNLYR[166.11].L sp|P35579|MYH9_HUMAN 1 1202.6171 1.17 16002 16311 2 1202.615855 602.3158 Myosin-9 OS=Homo sapiens OX=9606 GN=MYH9 PE=1 SV=4 4.37 3076.8 - 5.34E+06 - - - -1.012 - 2.017 0.098 - 550.2 1 2 0 -0.0012 10 0 0 0 1.74E+08 1.49E+08 - - - 1.7229 0.9996 221125_WJC_METTL3_EV_vs_WT_F02.16314.16314.2 0.0463 16-Aug R.AFSYYGPLR[166.11].T "sp|Q16629|SRSF7_HUMAN,tr|C9JAB2|C9JAB2_HUMAN,tr|A0A0B4J1Z1|A0A0B4J1Z1_HUMAN" 3 1082.5425 3.22 16004 16314 2 1082.5424 542.2785 Serine\arginine-rich splicing factor 7 OS=Homo sapiens OX=9606 GN=SRSF7 PE=1 SV=1 8.63 3077.1 - 2.79E+06 - - - -0.0471 - 1.697 0.374 - 249 1 2 0 -0.0001 9 0 0 0 4.75E+08 1.47E+08 - - - 3.3334 0.9957 221125_WJC_METTL3_EV_vs_WT_F02.16321.16321.2 0.0913 12-Jun K.DMYNIIR[166.11].L sp|P53701|CCHL_HUMAN 1 933.4618 1.19 16011 16321 2 933.461553 467.7382 Holocytochrome c-type synthase OS=Homo sapiens OX=9606 GN=HCCS PE=1 SV=1 5.84 3077.9 - 784074 - - - -0.2196 - 1.258 0.194 - 154.9 1 2 0 -0.0002 7 0 0 0 1.35E+07 1.14E+07 - - - 1.2011 0.9988 221125_WJC_METTL3_EV_vs_WT_F02.16324.16324.2 0.0212 18-Sep K.DINAVAASLR[166.11].K "sp|Q7L1Q6|BZW1_HUMAN,tr|C9JFN4|C9JFN4_HUMAN,tr|C9IZ80|C9IZ80_HUMAN" 3 1038.5697 0.12 16013 16324 2 1038.568455 520.2921 Basic leucine zipper and W2 domain-containing protein 1 OS=Homo sapiens OX=9606 GN=BZW1 PE=1 SV=1 5.84 3078.2 - 916837 - - - -1.2257 - 1.875 0.226 - 222.3 1 2 0 -0.0013 10 0 0 0 2.44E+06 2.12E+07 - - - 2.4645 0.9991 221125_WJC_METTL3_EV_vs_WT_F02.16327.16327.3 0.0357 15/44 R.YLYTLVITDK[136.11]EK[136.11].A "sp|P63173|RL38_HUMAN,tr|J3KT73|J3KT73_HUMAN,tr|J3QL01|J3QL01_HUMAN" 3 1500.841 0.9 16015 16327 3 1500.839932 501.2876 60S ribosomal protein L38 OS=Homo sapiens OX=9606 GN=RPL38 PE=1 SV=2 6.07 3078.5 - 2.18E+06 - - - -0.7429 - 2.104 0.357 - 193.4 1 2 1 -0.0011 12 0 0 0 5.20E+07 5.81E+07 - - - 4.5817 0.9993 221125_WJC_METTL3_EV_vs_WT_F02.16328.16328.2 0.000486 18-Oct R.VEVTEFEDIK.S "sp|Q01105|SET_HUMAN,sp|P0DME0|SETLP_HUMAN,tr|A0A0C4DFV9|A0A0C4DFV9_HUMAN" 3 1207.5972 0.94 16016 16328 2 1207.594502 604.8059 Protein SET OS=Homo sapiens OX=9606 GN=SET PE=1 SV=3 4 3078.6 - 1.84E+06 - - - -2.2632 - 1.809 0.399 - 390.1 1 2 0 -0.0027 10 0 0 0 6.54E+07 6.92E+07 - - - 3.6418 0.9944 221125_WJC_METTL3_EV_vs_WT_F02.16329.16329.2 9.11E-07 15/20 Y.TFIQNVPLEDR.V "sp|Q00839|HNRPU_HUMAN,tr|A0A1W2PQL0|A0A1W2PQL0_HUMAN,tr|A0A1W2PPL4|A0A1W2PPL4_HUMAN,tr|A0A1W2PQ74|A0A1W2PQ74_HUMAN,tr|Q5RI18|Q5RI18_HUMAN,tr|A0A1W2PP35|A0A1W2PP35_HUMAN,tr|A0A1W2PPS1|A0A1W2PPS1_HUMAN,tr|A0A1W2PRZ7|A0A1W2PRZ7_HUMAN,tr|A0A1W2PPH7|A0A1W2PPH7_HUMAN,tr|A0A1W2PP34|A0A1W2PP34_HUMAN,tr|A0A1X7SBS1|A0A1X7SBS1_HUMAN" 11 1330.6881 1.17 16017 16329 2 1330.68722 666.3513 Heterogeneous nuclear ribonucleoprotein U OS=Homo sapiens OX=9606 GN=HNRNPU PE=1 SV=6 4.37 3078.7 - 1.50E+06 - - - -0.6726 - 2.694 0.514 - 922 1 1 0 -0.0009 11 0 0 0 8.51E+07 7.26E+07 - - - 5.5181 0.9983 221125_WJC_METTL3_EV_vs_WT_F02.16332.16332.2 0.000434 18-Sep R.FEVAQVESLR[166.11].Y sp|P12270|TPR_HUMAN 1 1186.6222 2.18 16020 16332 2 1186.626825 594.3184 Nucleoprotein TPR OS=Homo sapiens OX=9606 GN=TPR PE=1 SV=3 4.53 3079 - 1.06E+06 - - - 3.933 - 2.043 0.427 - 301.6 1 2 0 0.0047 10 0 0 0 1.04E+08 4.77E+07 - - - 4.1875 0.9999 221125_WJC_METTL3_EV_vs_WT_F02.16339.16339.3 0.00289 Oct-40 R.FQELLASPAYR.A sp|Q9NSI2|SLX9_HUMAN 1 1293.6717 1.59 16025 16339 3 1293.671921 432.2312 Ribosome biogenesis protein SLX9 homolog OS=Homo sapiens OX=9606 GN=SLX9 PE=1 SV=2 6 3079.8 - 2.67E+06 - - - 0.1422 - 2.118 0.379 - 171.5 1 2 0 0.0002 11 0 0 0 4.77E+07 2.99E+07 - - - 4.8974 0.8707 221125_WJC_METTL3_EV_vs_WT_F02.16340.16340.2 0.388 16-May K.IVIPTDLER[166.11].L "sp|P56962|STX17_HUMAN,tr|E9PJV6|E9PJV6_HUMAN,tr|E9PIC2|E9PIC2_HUMAN,tr|E9PJW1|E9PJW1_HUMAN,tr|E9PQU9|E9PQU9_HUMAN" 5 1064.6105 3.71 16026 16340 2 1064.604765 533.3125 Syntaxin-17 OS=Homo sapiens OX=9606 GN=STX17 PE=1 SV=2 4.37 3079.8 - 2.72E+06 - - - -5.4151 - 1.409 0.161 - 57.9 3 2 0 -0.0058 9 0 0 0 1.16E+08 3.13E+07 - - - 1.0072 1 221125_WJC_METTL3_EV_vs_WT_F02.16342.16342.2 1.92E-08 24-Nov K.PYMTVSSEFPAAR.L "sp|Q6W2J9|BCOR_HUMAN,tr|H7BZ37|H7BZ37_HUMAN,tr|H7C2V9|H7C2V9_HUMAN,tr|H7BYY2|H7BYY2_HUMAN,tr|H7C231|H7C231_HUMAN" 5 1454.6864 5.01 16028 16342 2 1454.685251 728.3505 BCL-6 corepressor OS=Homo sapiens OX=9606 GN=BCOR PE=1 SV=1 6.43 3080.1 - 832953 - - - -0.7905 - 2.368 0.65 - 365.1 1 1 0 -0.0011 13 0 0 0 1.04E+07 2.08E+06 - - - 6.054 0.9995 221125_WJC_METTL3_EV_vs_WT_F02.16343.16343.2 0.000364 16-Oct K.SAFLC[160.03]GVMK.T "sp|O60506|HNRPQ_HUMAN,sp|O43390|HNRPR_HUMAN,tr|A0A7I2YQV8|A0A7I2YQV8_HUMAN,tr|A0A7I2YQN2|A0A7I2YQN2_HUMAN,tr|A0A7I2V5Q6|A0A7I2V5Q6_HUMAN,tr|A0A7I2V4Z0|A0A7I2V4Z0_HUMAN,tr|A0A6Q8PH31|A0A6Q8PH31_HUMAN,tr|A0A7I2V4J0|A0A7I2V4J0_HUMAN,tr|F6UXX1|F6UXX1_HUMAN,tr|A0A7I2V346|A0A7I2V346_HUMAN,tr|A0A6Q8PH35|A0A6Q8PH35_HUMAN" 11 1011.4882 1.46 16029 16343 2 1011.486596 506.7514 Heterogeneous nuclear ribonucleoprotein Q OS=Homo sapiens OX=9606 GN=SYNCRIP PE=1 SV=2 7.94 3080.2 - 710793 - - - -1.5452 - 1.663 0.421 - 280.8 1 2 0 -0.0016 9 0 0 0 8.21E+07 5.63E+07 - - - 3.6215 0.9986 221125_WJC_METTL3_EV_vs_WT_F02.16347.16347.2 1.32E-05 18-Dec R.FGLNVSSISR.K "sp|P82979|SARNP_HUMAN,tr|F8VZQ9|F8VZQ9_HUMAN,tr|H0YHG0|H0YHG0_HUMAN" 3 1078.5771 0.49 16031 16347 2 1078.581588 540.2958 SAP domain-containing ribonucleoprotein OS=Homo sapiens OX=9606 GN=SARNP PE=1 SV=3 9.75 3080.6 - 2.73E+06 - - - 4.1536 - 2.172 0.474 - 465.5 1 2 0 0.0045 10 0 0 0 4.57E+07 9.42E+07 - - - 4.7056 0.9999 221125_WJC_METTL3_EV_vs_WT_F02.16348.16348.2 5.59E-05 18-Dec R.FEVAQVESLR.Y sp|P12270|TPR_HUMAN 1 1176.6139 2.17 16032 16348 2 1176.613919 589.3142 Nucleoprotein TPR OS=Homo sapiens OX=9606 GN=TPR PE=1 SV=3 4.53 3080.7 - 4.77E+06 - - - 0.0263 - 2.321 0.461 - 601.3 1 2 0 0 10 0 0 0 1.06E+08 4.88E+07 - - - 4.7962 0.9991 221125_WJC_METTL3_EV_vs_WT_F02.16349.16349.2 0.0864 14-Aug K.TQIDELLR[166.11].Q "sp|P82094|TMF1_HUMAN,tr|A0A2R8Y7M0|A0A2R8Y7M0_HUMAN" 2 996.5479 1.5 16033 16349 2 996.548025 499.2812 TATA element modulatory factor OS=Homo sapiens OX=9606 GN=TMF1 PE=1 SV=2 4.37 3080.7 - 3.92E+06 - - - 0.0953 - 1.749 0.233 - 379.5 1 2 0 0.0001 8 0 0 0 1.63E+08 1.08E+08 - - - 2.448 0.9926 221125_WJC_METTL3_EV_vs_WT_F02.16350.16350.2 3.81E-06 20-Oct Y.TFIQNVPLEDR[166.11].V "sp|Q00839|HNRPU_HUMAN,tr|A0A1W2PQL0|A0A1W2PQL0_HUMAN,tr|A0A1W2PPL4|A0A1W2PPL4_HUMAN,tr|A0A1W2PQ74|A0A1W2PQ74_HUMAN,tr|Q5RI18|Q5RI18_HUMAN,tr|A0A1W2PP35|A0A1W2PP35_HUMAN,tr|A0A1W2PPS1|A0A1W2PPS1_HUMAN,tr|A0A1W2PRZ7|A0A1W2PRZ7_HUMAN,tr|A0A1W2PPH7|A0A1W2PPH7_HUMAN,tr|A0A1W2PP34|A0A1W2PP34_HUMAN,tr|A0A1X7SBS1|A0A1X7SBS1_HUMAN" 11 1340.6964 1.18 16034 16350 2 1340.696784 671.3555 Heterogeneous nuclear ribonucleoprotein U OS=Homo sapiens OX=9606 GN=HNRNPU PE=1 SV=6 4.37 3080.8 - 3.73E+06 - - - 0.2976 - 2.108 0.516 - 325.7 1 1 0 0.0004 11 0 0 0 8.57E+07 7.26E+07 - - - 4.8695 0.9993 221125_WJC_METTL3_EV_vs_WT_F02.16351.16351.2 0.00067 16-Sep K.LFEVIETEK.T "sp|P27448|MARK3_HUMAN,sp|Q96L34|MARK4_HUMAN,sp|Q9P0L2|MARK1_HUMAN,sp|Q7KZI7|MARK2_HUMAN,tr|A0A7I2V3C6|A0A7I2V3C6_HUMAN,tr|F5H6N2|F5H6N2_HUMAN,tr|A0A7I2V3P5|A0A7I2V3P5_HUMAN,tr|A0A7I2V5H7|A0A7I2V5H7_HUMAN,tr|K7EKG8|K7EKG8_HUMAN,tr|A0A0A0MRU9|A0A0A0MRU9_HUMAN,tr|A0A7I2V5G3|A0A7I2V5G3_HUMAN,tr|K7EK17|K7EK17_HUMAN,tr|A0A7I2YQF4|A0A7I2YQF4_HUMAN,tr|A0A7I2YQF7|A0A7I2YQF7_HUMAN,tr|A0A7I2V4K8|A0A7I2V4K8_HUMAN,tr|E7ETY4|E7ETY4_HUMAN,tr|A0A087X0I6|A0A087X0I6_HUMAN,tr|F5H4F6|F5H4F6_HUMAN,tr|A0A7I2V2U9|A0A7I2V2U9_HUMAN,tr|A0A7I2V4G7|A0A7I2V4G7_HUMAN,tr|H0YNV4|H0YNV4_HUMAN,tr|A0A7I2V2N8|A0A7I2V2N8_HUMAN,tr|H0YJI9|H0YJI9_HUMAN,tr|A0A7I2V409|A0A7I2V409_HUMAN,tr|A0A7I2V4T2|A0A7I2V4T2_HUMAN,tr|A0A7I2V4L1|A0A7I2V4L1_HUMAN,tr|A0A7I2YQR3|A0A7I2YQR3_HUMAN,tr|A0A7I2V549|A0A7I2V549_HUMAN,tr|E9PC69|E9PC69_HUMAN,tr|A0A7I2V3B9|A0A7I2V3B9_HUMAN,tr|A0A7I2V602|A0A7I2V602_HUMAN,tr|A0A7I2V639|A0A7I2V639_HUMAN,tr|A0A7I2YQC1|A0A7I2YQC1_HUMAN,tr|A0A7I2V3R3|A0A7I2V3R3_HUMAN,tr|B4DIB3|B4DIB3_HUMAN,tr|A0A7I2V2I9|A0A7I2V2I9_HUMAN,tr|J3KNR0|J3KNR0_HUMAN,tr|H0YKP9|H0YKP9_HUMAN" 38 1106.5859 1.73 16035 16351 2 1106.584686 554.3002 MAP\microtubule affinity-regulating kinase 3 OS=Homo sapiens OX=9606 GN=MARK3 PE=1 SV=5 4.25 3080.8 - 2.74E+06 - - - -1.135 - 1.752 0.302 - 201.7 1 2 0 -0.0013 9 0 0 0 4.39E+07 2.53E+07 - - - 2.8935 0.9981 221125_WJC_METTL3_EV_vs_WT_F02.16352.16352.2 0.0309 12-Aug K.FDIELGR.G "sp|Q9BYP7|WNK3_HUMAN,sp|Q9H4A3|WNK1_HUMAN,sp|Q96J92|WNK4_HUMAN,sp|Q9Y3S1|WNK2_HUMAN,tr|F5GWT4|F5GWT4_HUMAN,tr|A0A087WYK2|A0A087WYK2_HUMAN,tr|A6PVV2|A6PVV2_HUMAN,tr|K7ENT7|K7ENT7_HUMAN,tr|F8W9F9|F8W9F9_HUMAN,tr|H0Y7T5|H0Y7T5_HUMAN,tr|B1AQN8|B1AQN8_HUMAN,tr|F6UYG0|F6UYG0_HUMAN" 12 848.4392 1.56 16036 16352 2 848.437796 425.2269 Serine\threonine-protein kinase WNK3 OS=Homo sapiens OX=9606 GN=WNK3 PE=1 SV=3 4.37 3080.9 - 2.30E+06 - - - -1.676 - 1.668 0.222 - 225.1 1 2 0 -0.0014 7 0 0 0 3.82E+07 2.45E+07 - - - 2.3014 0.9997 221125_WJC_METTL3_EV_vs_WT_F02.16354.16354.2 0.000127 16-Aug K.GFGFVSYEK[136.11].H "sp|Q13310|PABP4_HUMAN,tr|A0A7I2V5W9|A0A7I2V5W9_HUMAN,tr|B1ANR0|B1ANR0_HUMAN,tr|A0A7I2V4L7|A0A7I2V4L7_HUMAN,tr|H0YCC8|H0YCC8_HUMAN,tr|A0A7I2V598|A0A7I2V598_HUMAN,tr|H0Y5F5|H0Y5F5_HUMAN" 7 1040.5058 1.37 16038 16354 2 1040.507309 521.2602 Polyadenylate-binding protein 4 OS=Homo sapiens OX=9606 GN=PABPC4 PE=1 SV=1 6 3081.1 - 1.34E+06 - - - 1.4051 - 1.841 0.464 - 191.5 1 2 0 0.0015 9 0 0 0 2.42E+08 1.77E+08 - - - 4.2333 0.9994 221125_WJC_METTL3_EV_vs_WT_F02.16355.16355.2 0.00137 14-Jul K.NFEWVAER.V "sp|P22234|PUR6_HUMAN,tr|D6RF62|D6RF62_HUMAN,tr|E9PBS1|E9PBS1_HUMAN" 3 1049.493 0.97 16039 16355 2 1049.493384 525.7538 Multifunctional protein ADE2 OS=Homo sapiens OX=9606 GN=PAICS PE=1 SV=3 4.53 3081.1 - 1.22E+06 - - - 0.324 - 1.63 0.331 - 242.1 1 2 0 0.0003 8 0 0 0 2.62E+07 2.71E+07 - - - 2.9592 0.9991 221125_WJC_METTL3_EV_vs_WT_F02.16356.16356.2 2.64E-05 18-Oct R.IVEVDGMDLR.D "sp|O75970|MPDZ_HUMAN,tr|B7ZB24|B7ZB24_HUMAN,tr|F5H1U9|F5H1U9_HUMAN" 3 1145.5751 2.27 16040 16356 2 1145.57186 573.7948 Multiple PDZ domain protein OS=Homo sapiens OX=9606 GN=MPDZ PE=1 SV=2 4.03 3081.2 - 748474 - - - -2.7925 - 2.007 0.383 - 257.6 1 2 0 -0.0032 10 0 0 0 6.55E+06 2.89E+06 - - - 3.8134 0.9999 221125_WJC_METTL3_EV_vs_WT_F02.16357.16357.2 0.000887 13/24 R.VALGETQLVQEVR.R sp|Q9Y4C8|RBM19_HUMAN 1 1440.7936 1.4 16041 16357 2 1440.794464 721.4041 Probable RNA-binding protein 19 OS=Homo sapiens OX=9606 GN=RBM19 PE=1 SV=3 4.53 3081.4 - 725939 - - - 0.5698 - 2.753 0.475 - 746.1 1 2 0 0.0008 13 0 0 0 8.92E+06 6.37E+06 - - - 5.1482 0.9951 221125_WJC_METTL3_EV_vs_WT_F02.16358.16358.2 0.223 16-Aug K.GAIENLLAK[136.11].L "sp|Q9UPN9|TRI33_HUMAN,tr|H0Y612|H0Y612_HUMAN" 2 935.5531 0.89 16042 16358 2 935.553173 468.7838 E3 ubiquitin-protein ligase TRIM33 OS=Homo sapiens OX=9606 GN=TRIM33 PE=1 SV=3 6 3081.5 - 714150 - - - 0.0438 - 1.526 0.116 - 131.9 1 2 0 0 9 0 0 0 6.50E+06 7.27E+06 - - - 1.1205 0.9672 221125_WJC_METTL3_EV_vs_WT_F02.16359.16359.2 0.505 16-Aug K.GAIENLLAK.L "sp|Q9UPN9|TRI33_HUMAN,tr|H0Y612|H0Y612_HUMAN" 2 927.5389 0.89 16043 16359 2 927.535027 464.7767 E3 ubiquitin-protein ligase TRIM33 OS=Homo sapiens OX=9606 GN=TRIM33 PE=1 SV=3 6 3081.6 - 566741 - - - -4.2101 - 1.618 0.138 - 114.4 1 2 0 -0.0039 9 0 0 0 6.34E+06 7.11E+06 - - - 1.4512 0.9998 221125_WJC_METTL3_EV_vs_WT_F02.16363.16363.2 2.63E-06 13/20 R.MGAGMGFGLER[166.11].M "sp|P52272|HNRPM_HUMAN,tr|M0R2I7|M0R2I7_HUMAN,tr|A0A087X0X3|A0A087X0X3_HUMAN,tr|M0QZM1|M0QZM1_HUMAN" 4 1134.519 1.52 16045 16363 2 1134.518521 568.2668 Heterogeneous nuclear ribonucleoprotein M OS=Homo sapiens OX=9606 GN=HNRNPM PE=1 SV=3 5.75 3082.1 - 1.15E+07 - - - -0.3825 - 2.418 0.385 - 792.3 1 2 0 -0.0004 11 0 0 0 6.90E+08 4.55E+08 - - - 4.273 0.9993 221125_WJC_METTL3_EV_vs_WT_F02.16364.16364.2 0.034 14-Jul K.TQIDELLR.Q "sp|P82094|TMF1_HUMAN,tr|A0A2R8Y7M0|A0A2R8Y7M0_HUMAN" 2 986.5397 1.5 16046 16364 2 986.539217 494.2771 TATA element modulatory factor OS=Homo sapiens OX=9606 GN=TMF1 PE=1 SV=2 4.37 3082.2 - 8.50E+06 - - - -0.449 - 1.453 0.34 - 236.1 1 2 0 -0.0004 8 0 0 0 1.63E+08 1.09E+08 - - - 2.679 0.9997 221125_WJC_METTL3_EV_vs_WT_F02.16365.16365.2 0.00368 20-Dec K.LVLLGESAVGK[136.11].S "sp|P61020|RAB5B_HUMAN,sp|P20339|RAB5A_HUMAN,sp|P51148|RAB5C_HUMAN,tr|F8VVZ0|F8VVZ0_HUMAN,tr|F8VWZ7|F8VWZ7_HUMAN,tr|K7ERI8|K7ERI8_HUMAN,tr|F8VPW9|F8VPW9_HUMAN,tr|F8VSF8|F8VSF8_HUMAN,tr|F8WCY6|F8WCY6_HUMAN,tr|F8WD79|F8WD79_HUMAN,tr|F8VUA5|F8VUA5_HUMAN,tr|K7ERQ8|K7ERQ8_HUMAN,tr|F8VWU4|F8VWU4_HUMAN,tr|F8VVK3|F8VVK3_HUMAN" 14 1092.6634 1.1 16047 16365 2 1092.662239 547.339 Ras-related protein Rab-5B OS=Homo sapiens OX=9606 GN=RAB5B PE=1 SV=1 6 3082.2 - 5.30E+06 - - - -1.0726 - 2.389 0.341 - 490.3 1 2 0 -0.0012 11 0 0 0 9.82E+07 8.91E+07 - - - 3.9152 0.9999 221125_WJC_METTL3_EV_vs_WT_F02.16366.16366.2 4.97E-06 20-Dec K.VISVDELEYR[166.11]Q.- "sp|Q9NRA8|4ET_HUMAN,tr|B1AKL4|B1AKL4_HUMAN" 2 1359.691 1.47 16048 16366 2 1359.690865 680.8528 Eukaryotic translation initiation factor 4E transporter OS=Homo sapiens OX=9606 GN=EIF4ENIF1 PE=1 SV=2 4.14 3082.3 - 4.53E+06 - - - -0.0743 - 2.281 0.553 - 473.6 1 2 0 -0.0001 11 0 0 0 1.67E+08 1.14E+08 - - - 5.3562 0.9996 221125_WJC_METTL3_EV_vs_WT_F02.16367.16367.2 0.0108 20-Sep K.LLLLGAGESGK[136.11].S "sp|P19087|GNAT2_HUMAN,sp|P63092|GNAS2_HUMAN,sp|A8MTJ3|GNAT3_HUMAN,sp|Q03113|GNA12_HUMAN,sp|Q14344|GNA13_HUMAN,sp|P63096|GNAI1_HUMAN,sp|P04899|GNAI2_HUMAN,sp|P08754|GNAI3_HUMAN,sp|P38405|GNAL_HUMAN,sp|P09471|GNAO_HUMAN,sp|Q5JWF2|GNAS1_HUMAN,sp|P11488|GNAT1_HUMAN,tr|A0A590UJS2|A0A590UJS2_HUMAN,tr|A0A6Q8PGR1|A0A6Q8PGR1_HUMAN,tr|Q5JWE9|Q5JWE9_HUMAN,tr|A0A1W2PQK2|A0A1W2PQK2_HUMAN,tr|A0A1W2PRJ7|A0A1W2PRJ7_HUMAN,tr|A2A2R6|A2A2R6_HUMAN,tr|Q5JWD1|Q5JWD1_HUMAN,tr|A0A3B3IUA8|A0A3B3IUA8_HUMAN,tr|A0A7I2V5R6|A0A7I2V5R6_HUMAN,tr|A0A1W2PRE1|A0A1W2PRE1_HUMAN,tr|H0Y7E8|H0Y7E8_HUMAN,tr|A0A1W2PS82|A0A1W2PS82_HUMAN,tr|A0A087WTB6|A0A087WTB6_HUMAN,tr|A0A087WZE5|A0A087WZE5_HUMAN" 26 1064.6321 1.16 16049 16367 2 1064.629947 533.3233 Guanine nucleotide-binding protein G(t) subunit alpha-2 OS=Homo sapiens OX=9606 GN=GNAT2 PE=1 SV=4 6 3082.3 - 4.11E+06 - - - -2.0317 - 2.091 0.431 - 216.1 1 2 0 -0.0022 11 0 0 0 1.46E+08 1.26E+08 - - - 4.2192 0.9962 221125_WJC_METTL3_EV_vs_WT_F02.16368.16368.2 6.82E-05 16-Oct K.GFGFVSYEK.H "sp|Q13310|PABP4_HUMAN,tr|A0A7I2V5W9|A0A7I2V5W9_HUMAN,tr|B1ANR0|B1ANR0_HUMAN,tr|A0A7I2V4L7|A0A7I2V4L7_HUMAN,tr|H0YCC8|H0YCC8_HUMAN,tr|A0A7I2V598|A0A7I2V598_HUMAN,tr|H0Y5F5|H0Y5F5_HUMAN" 7 1032.4916 1.37 16050 16368 2 1032.497598 517.2531 Polyadenylate-binding protein 4 OS=Homo sapiens OX=9606 GN=PABPC4 PE=1 SV=1 6 3082.4 - 2.65E+06 - - - 5.7637 - 2.147 0.503 - 288.8 1 2 0 0.006 9 0 0 0 2.42E+08 1.77E+08 - - - 4.9648 0.9987 221125_WJC_METTL3_EV_vs_WT_F02.16369.16369.2 0.0268 18-Nov K.EIEAEIQALR.Q "sp|P07197|NFM_HUMAN,tr|E7ESP9|E7ESP9_HUMAN,tr|E7EMV2|E7EMV2_HUMAN" 3 1170.6245 4.37 16051 16369 2 1170.62801 586.3195 Neurofilament medium polypeptide OS=Homo sapiens OX=9606 GN=NEFM PE=1 SV=3 4.25 3082.4 - 2.25E+06 - - - 3.0394 - 1.963 0.367 - 481 1 2 0 0.0036 10 0 0 0 1.45E+08 3.33E+07 - - - 3.6332 0.9999 221125_WJC_METTL3_EV_vs_WT_F02.16370.16370.2 0.000116 16-Nov K.APGFAQMLK[136.11].E sp|P50990|TCPQ_HUMAN 1 969.5197 0.32 16052 16370 2 969.519648 485.7671 T-complex protein 1 subunit theta OS=Homo sapiens OX=9606 GN=CCT8 PE=1 SV=4 8.8 3082.5 - 1.87E+06 - - - -0.0774 - 2.132 0.509 - 403.9 1 2 0 -0.0001 9 0 0 0 4.33E+08 1.35E+09 - - - 4.9907 0.9921 221125_WJC_METTL3_EV_vs_WT_F02.16371.16371.2 0.0147 14-Aug R.FDITIGPK.Q sp|Q9Y2T2|AP3M1_HUMAN 1 889.4909 0.68 16053 16371 2 889.491079 445.7527 AP-3 complex subunit mu-1 OS=Homo sapiens OX=9606 GN=AP3M1 PE=1 SV=1 5.84 3082.6 - 746257 - - - 0.1799 - 1.53 0.063 - 171.3 1 2 0 0.0002 8 0 0 0 9.12E+06 1.34E+07 - - - 0.7889 0.9999 221125_WJC_METTL3_EV_vs_WT_F02.16372.16372.2 8.69E-05 22-Dec K.LDYDEDASAMLK[136.11].E "sp|P50502|F10A1_HUMAN,sp|Q8NFI4|F10A5_HUMAN,tr|H7C3I1|H7C3I1_HUMAN" 3 1377.6213 1.33 16054 16372 2 1377.619382 689.8179 Hsc70-interacting protein OS=Homo sapiens OX=9606 GN=ST13 PE=1 SV=2 3.84 3082.7 - 742153 - - - -1.4264 - 2.4 0.552 - 365.8 1 2 0 -0.002 12 0 0 0 2.88E+07 2.17E+07 - - - 5.421 0.9986 221125_WJC_METTL3_EV_vs_WT_F02.16373.16373.2 0.00824 14-Aug R.DAFVYAIK.N "sp|Q9HD45|TM9S3_HUMAN,tr|Q5TB53|Q5TB53_HUMAN" 2 925.4909 1.34 16055 16373 2 925.492131 463.7527 Transmembrane 9 superfamily member 3 OS=Homo sapiens OX=9606 GN=TM9SF3 PE=1 SV=2 5.83 3082.9 - 524484 - - - 1.3096 - 1.581 0.278 - 231.4 1 2 0 0.0012 8 0 0 0 7.64E+07 5.70E+07 - - - 2.4754 1 221125_WJC_METTL3_EV_vs_WT_F02.16376.16376.2 6.68E-07 13/20 R.MGAGMGFGLER.M "sp|P52272|HNRPM_HUMAN,tr|M0R2I7|M0R2I7_HUMAN,tr|A0A087X0X3|A0A087X0X3_HUMAN,tr|M0QZM1|M0QZM1_HUMAN" 4 1124.5107 1.52 16056 16376 2 1124.510996 563.2626 Heterogeneous nuclear ribonucleoprotein M OS=Homo sapiens OX=9606 GN=HNRNPM PE=1 SV=3 5.75 3083.3 - 2.17E+07 - - - 0.2766 - 2.419 0.599 - 772.4 1 2 0 0.0003 11 0 0 0 6.93E+08 4.55E+08 - - - 5.8548 0.9999 221125_WJC_METTL3_EV_vs_WT_F02.16378.16378.2 8.05E-05 13/22 K.LDYDEDASAMLK.E "sp|P50502|F10A1_HUMAN,sp|Q8NFI4|F10A5_HUMAN,tr|H7C3I1|H7C3I1_HUMAN" 3 1369.6071 1.33 16058 16378 2 1369.607504 685.8108 Hsc70-interacting protein OS=Homo sapiens OX=9606 GN=ST13 PE=1 SV=2 3.84 3083.4 - 1.26E+06 - - - 0.2607 - 2.598 0.558 - 453.1 1 2 0 0.0004 12 0 0 0 2.88E+07 2.17E+07 - - - 5.6744 0.9995 221125_WJC_METTL3_EV_vs_WT_F02.16379.16379.2 3.84E-07 22-Dec R.WTDENIDTVALK[136.11].H "sp|Q14204|DYHC1_HUMAN,tr|A0A7P0T8N2|A0A7P0T8N2_HUMAN,tr|A0A7P0T9C4|A0A7P0T9C4_HUMAN,tr|A0A7P0TBJ7|A0A7P0TBJ7_HUMAN,tr|A0A804HHY6|A0A804HHY6_HUMAN,tr|A0A7P0T9K2|A0A7P0T9K2_HUMAN,tr|A0A7P0TB64|A0A7P0TB64_HUMAN,tr|A0A2R8Y706|A0A2R8Y706_HUMAN,tr|A0A7P0T916|A0A7P0T916_HUMAN,tr|A0A7P0TB75|A0A7P0TB75_HUMAN,tr|A0A7P0T8W5|A0A7P0T8W5_HUMAN,tr|A0A7P0TAF3|A0A7P0TAF3_HUMAN,tr|A0A7P0T9F1|A0A7P0T9F1_HUMAN,tr|A0A7P0TAW9|A0A7P0TAW9_HUMAN,tr|A0A7P0TA13|A0A7P0TA13_HUMAN,tr|A0A7P0TAV5|A0A7P0TAV5_HUMAN,tr|A0A7P0T7V5|A0A7P0T7V5_HUMAN,tr|A0A7P0T9R4|A0A7P0T9R4_HUMAN,tr|A0A2R8Y5T0|A0A2R8Y5T0_HUMAN,tr|A0A7P0T990|A0A7P0T990_HUMAN,tr|A0A2R8YFZ7|A0A2R8YFZ7_HUMAN,tr|A0A7P0T825|A0A7P0T825_HUMAN,tr|A0A2R8Y6H2|A0A2R8Y6H2_HUMAN,tr|A0A7P0TAM4|A0A7P0TAM4_HUMAN" 24 1411.7075 1.03 16059 16379 2 1411.707732 706.861 Cytoplasmic dynein 1 heavy chain 1 OS=Homo sapiens OX=9606 GN=DYNC1H1 PE=1 SV=5 4.03 3083.6 - 1.04E+06 - - - 0.1927 - 2.459 0.216 - 373.3 1 2 0 0.0003 12 0 0 0 2.47E+07 2.39E+07 - - - 3.0037 0.9996 221125_WJC_METTL3_EV_vs_WT_F02.16380.16380.2 0.000122 22-Aug R.FMC[160.03]SQLPNQVLK.S sp|Q9H223|EHD4_HUMAN 1 1463.7265 2.13 16060 16380 2 1463.727084 732.8705 EH domain-containing protein 4 OS=Homo sapiens OX=9606 GN=EHD4 PE=1 SV=1 8.22 3083.7 - 540852 - - - 0.4044 - 1.466 0.441 - 195.9 1 2 0 0.0006 12 0 0 0 7.57E+06 3.55E+06 - - - 3.3046 0.9994 221125_WJC_METTL3_EV_vs_WT_F02.16381.16381.2 0.001 14/24 R.VGILLDEASGVNK[136.11].N sp|Q01780|EXOSX_HUMAN 1 1321.7333 1.23 16061 16381 2 1321.73687 661.8739 Exosome component 10 OS=Homo sapiens OX=9606 GN=EXOSC10 PE=1 SV=2 4.37 3083.8 - 416883 - - - 2.7154 - 2.652 0.377 - 745 1 2 0 0.0036 13 0 0 0 3.11E+07 2.52E+07 - - - 4.3276 0.9997 221125_WJC_METTL3_EV_vs_WT_F02.16382.16382.2 0.000549 20-Oct K.QYPYNNLYLER.G sp|O95169|NDUB8_HUMAN 1 1471.7096 1.05 16062 16382 2 1471.710959 736.8621 "NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 8, mitochondrial OS=Homo sapiens OX=9606 GN=NDUFB8 PE=1 SV=1" 6 3083.9 - 400408 - - - 0.9377 - 1.782 0.434 - 370.7 1 2 0 0.0014 11 0 0 0 1.54E+07 1.47E+07 - - - 3.809 0.9964 221125_WJC_METTL3_EV_vs_WT_F02.16387.16387.2 0.151 20-Sep K.LVLLGESAVGK.S "sp|P61020|RAB5B_HUMAN,sp|P20339|RAB5A_HUMAN,sp|P51148|RAB5C_HUMAN,tr|F8VVZ0|F8VVZ0_HUMAN,tr|F8VWZ7|F8VWZ7_HUMAN,tr|K7ERI8|K7ERI8_HUMAN,tr|F8VPW9|F8VPW9_HUMAN,tr|F8VSF8|F8VSF8_HUMAN,tr|F8WCY6|F8WCY6_HUMAN,tr|F8WD79|F8WD79_HUMAN,tr|F8VUA5|F8VUA5_HUMAN,tr|K7ERQ8|K7ERQ8_HUMAN,tr|F8VWU4|F8VWU4_HUMAN,tr|F8VVK3|F8VVK3_HUMAN" 14 1084.6492 1.1 16065 16387 2 1084.649819 543.3319 Ras-related protein Rab-5B OS=Homo sapiens OX=9606 GN=RAB5B PE=1 SV=1 6 3084.5 - 6.39E+06 - - - 0.5605 - 1.697 0.127 - 218.4 1 2 0 0.0006 11 0 0 0 9.82E+07 8.91E+07 - - - 1.4095 0.9996 221125_WJC_METTL3_EV_vs_WT_F02.16388.16388.2 0.0969 16-Aug K.SAFLC[160.03]GVMK[136.11].T "sp|O60506|HNRPQ_HUMAN,sp|O43390|HNRPR_HUMAN,tr|A0A7I2YQV8|A0A7I2YQV8_HUMAN,tr|A0A7I2YQN2|A0A7I2YQN2_HUMAN,tr|A0A7I2V5Q6|A0A7I2V5Q6_HUMAN,tr|A0A7I2V4Z0|A0A7I2V4Z0_HUMAN,tr|A0A6Q8PH31|A0A6Q8PH31_HUMAN,tr|A0A7I2V4J0|A0A7I2V4J0_HUMAN,tr|F6UXX1|F6UXX1_HUMAN,tr|A0A7I2V346|A0A7I2V346_HUMAN,tr|A0A6Q8PH35|A0A6Q8PH35_HUMAN" 11 1019.5024 1.45 16066 16388 2 1019.502823 510.7585 Heterogeneous nuclear ribonucleoprotein Q OS=Homo sapiens OX=9606 GN=SYNCRIP PE=1 SV=2 7.94 3084.6 - 4.56E+06 - - - 0.4551 - 1.615 0.394 - 194.3 1 2 0 0.0005 9 0 0 0 8.18E+07 5.63E+07 - - - 3.3377 0.9984 221125_WJC_METTL3_EV_vs_WT_F02.16390.16390.2 0.92 14-Jul K.VNIDDLVK.V "sp|O95202|LETM1_HUMAN,tr|H0YM15|H0YM15_HUMAN" 2 914.5073 1.05 16068 16390 2 914.50739 458.2609 Mitochondrial proton\calcium exchanger protein OS=Homo sapiens OX=9606 GN=LETM1 PE=1 SV=1 4.21 3084.7 - 967375 - - - 0.1017 - 1.637 0.193 - 132 1 2 0 0.0001 8 0 0 0 1.81E+07 1.73E+07 - - - 1.9529 0.9998 221125_WJC_METTL3_EV_vs_WT_F02.16399.16399.3 0.000302 Oct-40 K.VISVDELEYRQ.- "sp|Q9NRA8|4ET_HUMAN,tr|B1AKL4|B1AKL4_HUMAN" 2 1349.6827 0.27 16075 16399 3 1349.682849 450.9015 Eukaryotic translation initiation factor 4E transporter OS=Homo sapiens OX=9606 GN=EIF4ENIF1 PE=1 SV=2 4.14 3085.9 - 894380 - - - 0.1134 - 1.96 0.374 - 98.1 1 2 0 0.0002 11 0 0 0 9.62E+06 3.63E+07 - - - 4.6214 0.9999 221125_WJC_METTL3_EV_vs_WT_F02.16401.16401.2 1.87E-06 18-Oct K.MFILSDGEGK[136.11].N "sp|P35244|RFA3_HUMAN,tr|B5MC59|B5MC59_HUMAN" 2 1103.5412 1.26 16077 16401 2 1103.541158 552.7779 Replication protein A 14 kDa subunit OS=Homo sapiens OX=9606 GN=RPA3 PE=1 SV=1 4.37 3086 - 1.83E+06 - - - -0.0797 - 1.952 0.487 - 360.5 1 2 0 -0.0001 10 0 0 0 3.41E+08 2.71E+08 - - - 4.5049 0.9997 221125_WJC_METTL3_EV_vs_WT_F02.16407.16407.2 0.00119 20-Nov R.TTYLVLDEADR.M "sp|P17844|DDX5_HUMAN,tr|A0A7I2V5F5|A0A7I2V5F5_HUMAN,tr|J3KRZ1|J3KRZ1_HUMAN,tr|J3QSF1|J3QSF1_HUMAN,tr|A0A7I2V507|A0A7I2V507_HUMAN,tr|J3KTA4|J3KTA4_HUMAN,tr|A0A0G2JLI4|A0A0G2JLI4_HUMAN,tr|A0A7I2V2S0|A0A7I2V2S0_HUMAN" 8 1294.6405 1.59 16081 16407 2 1294.643557 648.3275 Probable ATP-dependent RNA helicase DDX5 OS=Homo sapiens OX=9606 GN=DDX5 PE=1 SV=1 4.03 3086.8 - 2.55E+07 - - - 2.3644 - 2.141 0.521 - 489.8 1 2 0 0.0031 11 0 0 0 5.49E+08 3.45E+08 - - - 4.9476 0.9993 221125_WJC_METTL3_EV_vs_WT_F02.16408.16408.2 7.45E-06 20-Nov R.TTYLVLDEADR[166.11].M "sp|P17844|DDX5_HUMAN,tr|A0A7I2V5F5|A0A7I2V5F5_HUMAN,tr|J3KRZ1|J3KRZ1_HUMAN,tr|J3QSF1|J3QSF1_HUMAN,tr|A0A7I2V507|A0A7I2V507_HUMAN,tr|J3KTA4|J3KTA4_HUMAN,tr|A0A0G2JLI4|A0A0G2JLI4_HUMAN,tr|A0A7I2V2S0|A0A7I2V2S0_HUMAN" 8 1304.6488 1.61 16082 16408 2 1304.644187 653.3317 Probable ATP-dependent RNA helicase DDX5 OS=Homo sapiens OX=9606 GN=DDX5 PE=1 SV=1 4.03 3086.8 - 1.70E+07 - - - -3.5098 - 2.15 0.541 - 506.5 1 2 0 -0.0046 11 0 0 0 5.59E+08 3.47E+08 - - - 5.1062 0.9994 221125_WJC_METTL3_EV_vs_WT_F02.16409.16409.2 0.0247 16-Aug R.SPSWYGIPR.L "sp|P78347|GTF2I_HUMAN,tr|A0A494C0Q7|A0A494C0Q7_HUMAN,tr|A0A494C1K3|A0A494C1K3_HUMAN" 3 1061.5294 1.26 16083 16409 2 1061.529798 531.772 General transcription factor II-I OS=Homo sapiens OX=9606 GN=GTF2I PE=1 SV=2 8.46 3086.9 - 8.27E+06 - - - 0.3467 - 1.699 0.309 - 328.7 1 2 0 0.0004 9 0 0 0 8.39E+08 6.64E+08 - - - 2.8566 0.9997 221125_WJC_METTL3_EV_vs_WT_F02.16410.16410.2 0.00444 16-Sep K.FSSQELILR.R "sp|Q08188|TGM3_HUMAN,tr|A0A494C0J7|A0A494C0J7_HUMAN" 2 1091.5975 5.74 16084 16410 2 1091.598652 546.806 Protein-glutamine gamma-glutamyltransferase E OS=Homo sapiens OX=9606 GN=TGM3 PE=1 SV=4 6 3086.9 - 5.40E+06 - - - 1.0471 - 2.042 0.363 - 296.3 1 2 0 0.0011 9 0 0 0 1.00E+08 1.75E+07 - - - 3.7872 0.9996 221125_WJC_METTL3_EV_vs_WT_F02.16411.16411.2 0.0349 18-Sep K.MFILSDGEGK.N "sp|P35244|RFA3_HUMAN,tr|B5MC59|B5MC59_HUMAN" 2 1095.527 1.26 16085 16411 2 1095.527627 548.7708 Replication protein A 14 kDa subunit OS=Homo sapiens OX=9606 GN=RPA3 PE=1 SV=1 4.37 3086.9 - 3.35E+06 - - - 0.5303 - 1.877 0.365 - 273.1 1 2 0 0.0006 10 0 0 0 3.41E+08 2.71E+08 - - - 3.4943 0.9998 221125_WJC_METTL3_EV_vs_WT_F02.16412.16412.2 0.000147 16-Aug R.YNFFTGC[160.03]PK[136.11].A sp|Q99832|TCPH_HUMAN 1 1140.5154 0.25 16086 16412 2 1140.515199 571.265 T-complex protein 1 subunit eta OS=Homo sapiens OX=9606 GN=CCT7 PE=1 SV=2 8.2 3087 - 3.25E+06 - - - -0.1464 - 1.771 0.486 - 228.9 1 2 0 -0.0002 9 0 0 0 6.31E+07 2.54E+08 - - - 4.2841 0.9979 221125_WJC_METTL3_EV_vs_WT_F02.16414.16414.2 0.702 12-Jul R.WDLGLNK.K sp|Q92900|RENT1_HUMAN 1 844.4443 2.15 16088 16414 2 844.444312 423.2294 Regulator of nonsense transcripts 1 OS=Homo sapiens OX=9606 GN=UPF1 PE=1 SV=2 5.84 3087.1 - 1.88E+06 - - - 0.0107 - 1.321 0.249 - 174.1 1 2 0 0 7 0 0 0 9.30E+07 4.33E+07 - - - 1.7622 0.9983 221125_WJC_METTL3_EV_vs_WT_F02.16415.16415.2 0.0204 16-Jul R.GIEDIIVSK[136.11].R "sp|Q9BZJ0|CRNL1_HUMAN,tr|Q5JY65|Q5JY65_HUMAN" 2 980.5634 0.67 16089 16415 2 980.561362 491.289 Crooked neck-like protein 1 OS=Homo sapiens OX=9606 GN=CRNKL1 PE=1 SV=4 4.37 3087.2 - 1.27E+06 - - - -2.0396 - 1.632 0.295 - 114.8 1 2 0 -0.002 9 0 0 0 2.11E+07 3.12E+07 - - - 2.6363 0.9143 221125_WJC_METTL3_EV_vs_WT_F02.16416.16416.2 0.134 14-Jul R.SPSELFAQ.H "sp|Q9Y2W1|TR150_HUMAN,tr|A0A3B3ITZ9|A0A3B3ITZ9_HUMAN" 2 877.4181 - 16090 16416 2 877.417579 439.7164 Thyroid hormone receptor-associated protein 3 OS=Homo sapiens OX=9606 GN=THRAP3 PE=1 SV=2 4 3087.3 - 1.11E+06 - - - -0.6485 - 1.353 0.283 - 206.4 1 1 0 -0.0006 8 0 0 0 - - - - - 2.0429 1 221125_WJC_METTL3_EV_vs_WT_F02.16417.16417.2 4.08E-09 15/22 R.C[160.03]LYASVLTAQPR[166.11].L sp|P13639|EF2_HUMAN 1 1387.7157 0.52 16091 16417 2 1387.718604 694.8651 Elongation factor 2 OS=Homo sapiens OX=9606 GN=EEF2 PE=1 SV=4 8.22 3087.5 - 831755 - - - 2.0631 - 2.532 0.663 - 784.8 1 2 0 0.0029 12 0 0 0 4.20E+07 8.04E+07 - - - 6.3814 0.9998 221125_WJC_METTL3_EV_vs_WT_F02.16419.16419.2 3.02E-05 20-Nov K.QYPYNNLYLER[166.11].G sp|O95169|NDUB8_HUMAN 1 1481.7178 0.84 16093 16419 2 1481.715248 741.8662 "NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 8, mitochondrial OS=Homo sapiens OX=9606 GN=NDUFB8 PE=1 SV=1" 6 3087.7 - 719641 - - - -1.7554 - 1.869 0.547 - 463 1 2 0 -0.0026 11 0 0 0 7.70E+06 9.17E+06 - - - 4.7722 0.9985 221125_WJC_METTL3_EV_vs_WT_F02.16422.16422.3 0.0281 Oct-40 K.VISVDELEYR[166.11]Q.- "sp|Q9NRA8|4ET_HUMAN,tr|B1AKL4|B1AKL4_HUMAN" 2 1359.691 1.21 16096 16422 3 1359.690455 454.2376 Eukaryotic translation initiation factor 4E transporter OS=Homo sapiens OX=9606 GN=EIF4ENIF1 PE=1 SV=2 4.14 3088.1 - 461723 - - - -0.3758 - 1.887 0.241 - 135.6 1 2 0 -0.0005 11 0 0 0 9.07E+06 7.49E+06 - - - 3.0307 0.999 221125_WJC_METTL3_EV_vs_WT_F02.16425.16425.2 0.00606 16-Sep K.APGFAQMLK.E sp|P50990|TCPQ_HUMAN 1 961.5055 0.32 16098 16425 2 961.505156 481.76 T-complex protein 1 subunit theta OS=Homo sapiens OX=9606 GN=CCT8 PE=1 SV=4 8.8 3088.5 - 7.68E+06 - - - -0.3817 - 1.544 0.285 - 243.9 1 2 0 -0.0004 9 0 0 0 4.32E+08 1.35E+09 - - - 2.4026 0.9998 221125_WJC_METTL3_EV_vs_WT_F02.16427.16427.2 0.00126 16-Aug R.SPSWYGIPR[166.11].L "sp|P78347|GTF2I_HUMAN,tr|A0A494C0Q7|A0A494C0Q7_HUMAN,tr|A0A494C1K3|A0A494C1K3_HUMAN" 3 1071.5377 1.28 16099 16427 2 1071.537537 536.7761 General transcription factor II-I OS=Homo sapiens OX=9606 GN=GTF2I PE=1 SV=2 8.46 3088.7 - 9.94E+06 - - - -0.1521 - 1.952 0.462 - 366.4 1 2 0 -0.0002 9 0 0 0 8.72E+08 6.83E+08 - - - 4.3883 0.9991 221125_WJC_METTL3_EV_vs_WT_F02.16428.16428.2 0.0242 12-Jul R.WDLGLNK[136.11].K sp|Q92900|RENT1_HUMAN 1 852.4585 1.94 16100 16428 2 852.458331 427.2365 Regulator of nonsense transcripts 1 OS=Homo sapiens OX=9606 GN=UPF1 PE=1 SV=2 5.84 3088.7 - 2.88E+06 - - - -0.2018 - 1.351 0.337 - 174.9 1 2 0 -0.0002 7 0 0 0 8.33E+07 4.29E+07 - - - 2.4833 0.8929 221125_WJC_METTL3_EV_vs_WT_F02.16431.16431.2 2.63 18-Jun R.QMQLEDGGQL.- sp|Q9NSI2|SLX9_HUMAN 1 1117.5074 - 16103 16431 2 1117.508455 559.761 Ribosome biogenesis protein SLX9 homolog OS=Homo sapiens OX=9606 GN=SLX9 PE=1 SV=2 3.67 3088.9 - 1.65E+06 - - - 0.9673 - 0.881 0.072 - 85 1 2 0 0.0011 10 0 0 0 - - - - - -0.7812 1 221125_WJC_METTL3_EV_vs_WT_F02.16433.16433.2 2.61E-07 18/34 K.PSTASAVPELATDPELEK[136.11].K "sp|Q86U44|MTA70_HUMAN,tr|B4E349|B4E349_HUMAN,tr|F5H6D8|F5H6D8_HUMAN,tr|H0YFV6|H0YFV6_HUMAN,tr|B4DTN4|B4DTN4_HUMAN" 5 1861.94 0.001 16105 16433 2 1861.936487 931.9773 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 4 3089.1 - 670128 - - - -1.9077 - 2.869 0.579 - 616 1 1 0 -0.0036 18 0 0 0 0.00E+00 1.44E+07 - - - 5.9076 0.9998 221125_WJC_METTL3_EV_vs_WT_F02.16434.16434.2 0.00019 22-Dec K.LIVTSATLDAVK[136.11].F "sp|Q14562|DHX8_HUMAN,tr|F5H658|F5H658_HUMAN" 2 1237.7373 0.99 16106 16434 2 1237.738693 619.8759 ATP-dependent RNA helicase DHX8 OS=Homo sapiens OX=9606 GN=DHX8 PE=1 SV=1 5.84 3089.2 - 569575 - - - 1.1222 - 2.232 0.458 - 318.5 1 2 0 0.0014 12 0 0 0 7.08E+06 7.13E+06 - - - 4.5359 0.9989 221125_WJC_METTL3_EV_vs_WT_F02.16435.16435.2 0.0814 22-Oct K.LIVTSATLDAVK.F "sp|Q14562|DHX8_HUMAN,tr|F5H658|F5H658_HUMAN" 2 1229.7231 0.99 16107 16435 2 1229.722214 615.8688 ATP-dependent RNA helicase DHX8 OS=Homo sapiens OX=9606 GN=DHX8 PE=1 SV=1 5.84 3089.4 - 443518 - - - -0.7237 - 1.546 0.294 - 190.9 1 2 0 -0.0009 12 0 0 0 7.08E+06 7.13E+06 - - - 2.3585 0.9862 221125_WJC_METTL3_EV_vs_WT_F02.16438.16438.2 0.0294 28-Feb K.VVYSGDTMPC[160.03]EALVR[166.11].M "sp|Q9BQ52|RNZ2_HUMAN,tr|G5E9D5|G5E9D5_HUMAN,tr|E7ES68|E7ES68_HUMAN" 3 1705.8043 0.25 16110 16438 2 1705.800766 853.9094 Zinc phosphodiesterase ELAC protein 2 OS=Homo sapiens OX=9606 GN=ELAC2 PE=1 SV=2 4.37 3089.8 - 185475 - - - -2.0706 - 1.002 0.322 - 5.7 11 2 0 -0.0035 15 0 0 0 2.75E+05 1.12E+06 - - - 0.9579 0.9436 221125_WJC_METTL3_EV_vs_WT_F02.16441.16441.2 0.000653 14-Jul Q.EMTLDEWK.N "sp|Q5JVS0|HABP4_HUMAN,sp|Q8NC51|PAIRB_HUMAN" 2 1050.4692 0.73 16112 16441 2 1050.467752 526.2419 Intracellular hyaluronan-binding protein 4 OS=Homo sapiens OX=9606 GN=HABP4 PE=1 SV=1 4.14 3090.1 - 7.47E+06 - - - -1.3756 - 1.447 0.346 - 277.5 1 1 0 -0.0014 8 0 0 0 2.50E+08 3.44E+08 - - - 2.7105 0.9983 221125_WJC_METTL3_EV_vs_WT_F02.16443.16443.2 0.0123 16-Jul R.ILDSAEFIK[136.11].F "sp|P78347|GTF2I_HUMAN,tr|A0A494C1K3|A0A494C1K3_HUMAN" 2 1042.579 1.43 16113 16443 2 1042.579236 522.2968 General transcription factor II-I OS=Homo sapiens OX=9606 GN=GTF2I PE=1 SV=2 4.37 3090.3 - 9.97E+06 - - - 0.2149 - 1.401 0.258 - 99.2 1 2 0 0.0002 9 0 0 0 2.53E+08 1.77E+08 - - - 1.922 0.9998 221125_WJC_METTL3_EV_vs_WT_F02.16445.16445.2 0.00564 16-Sep R.ILDSAEFIK.F "sp|P78347|GTF2I_HUMAN,tr|A0A494C1K3|A0A494C1K3_HUMAN" 2 1034.5648 1.42 16115 16445 2 1034.564459 518.2897 General transcription factor II-I OS=Homo sapiens OX=9606 GN=GTF2I PE=1 SV=2 4.37 3090.4 - 1.53E+07 - - - -0.3412 - 1.679 0.47 - 194.2 1 2 0 -0.0004 9 0 0 0 2.53E+08 1.78E+08 - - - 4.0115 0.9999 221125_WJC_METTL3_EV_vs_WT_F02.16446.16446.2 7.24E-07 13/22 R.C[160.03]LYASVLTAQPR.L sp|P13639|EF2_HUMAN 1 1377.7075 0.52 16116 16446 2 1377.705526 689.861 Elongation factor 2 OS=Homo sapiens OX=9606 GN=EEF2 PE=1 SV=4 8.22 3090.5 - 1.48E+06 - - - -1.4118 - 2.44 0.569 - 506.3 1 2 0 -0.0019 12 0 0 0 4.20E+07 8.04E+07 - - - 5.59 0.9981 221125_WJC_METTL3_EV_vs_WT_F02.16448.16448.2 0.00303 20-Oct K.ATLDMPDEEFR[166.11].F "sp|Q9H7E9|CH033_HUMAN,tr|A0A3B3IT54|A0A3B3IT54_HUMAN" 2 1332.5895 1.06 16118 16448 2 1332.593258 667.302 UPF0488 protein C8orf33 OS=Homo sapiens OX=9606 GN=C8orf33 PE=1 SV=1 3.92 3090.7 - 897785 - - - 2.7923 - 1.842 0.323 - 283.1 1 2 0 0.0037 11 0 0 0 1.12E+07 1.06E+07 - - - 3.078 0.9189 221125_WJC_METTL3_EV_vs_WT_F02.16455.16455.2 0.0384 16-Jun R.YDPQTNEWR.M sp|Q9Y2M5|KLH20_HUMAN 1 1207.5258 61.85 16123 16455 2 1207.533205 604.7702 Kelch-like protein 20 OS=Homo sapiens OX=9606 GN=KLHL20 PE=1 SV=4 4.37 3091.6 - 2.17E+06 - - - 6.1315 - 1.258 0.279 - 103.1 1 2 0 0.0074 9 0 0 0 2.27E+07 3.66E+05 - - - 1.7634 0.9915 221125_WJC_METTL3_EV_vs_WT_F02.16456.16456.2 0.000659 14-Nov A.PGFAQMLK[136.11].E sp|P50990|TCPQ_HUMAN 1 898.4826 0.35 16124 16456 2 898.482372 450.2486 T-complex protein 1 subunit theta OS=Homo sapiens OX=9606 GN=CCT8 PE=1 SV=4 9.18 3091.7 - 1.11E+06 - - - -0.2638 - 2.218 0.423 - 366.1 1 1 0 -0.0002 8 0 0 0 9.74E+06 2.79E+07 - - - 4.5677 0.9995 221125_WJC_METTL3_EV_vs_WT_F02.16457.16457.2 0.000638 20-Sep K.GVWSTLPVNEK[136.11].K "sp|Q96MU7|YTDC1_HUMAN,tr|J3QR07|J3QR07_HUMAN" 2 1236.6594 2.72 16125 16457 2 1236.659796 619.337 YTH domain-containing protein 1 OS=Homo sapiens OX=9606 GN=YTHDC1 PE=1 SV=3 6 3091.8 - 891887 - - - 0.3299 - 1.793 0.326 - 182.2 1 2 0 0.0004 11 0 0 0 2.76E+07 1.01E+07 - - - 3.0283 0.9931 221125_WJC_METTL3_EV_vs_WT_F02.16458.16458.2 0.0487 14-Jun R.FNNGWMIK.L "sp|Q8WV92|MITD1_HUMAN,tr|B8ZZL5|B8ZZL5_HUMAN,tr|H7C3Q6|H7C3Q6_HUMAN" 3 1008.4851 0.42 16126 16458 2 1008.48631 505.2498 MIT domain-containing protein 1 OS=Homo sapiens OX=9606 GN=MITD1 PE=1 SV=1 8.75 3091.9 - 724627 - - - 1.178 - 1.169 0.22 - 76.1 1 2 0 0.0012 8 0 0 0 2.51E+07 6.04E+07 - - - 1.1365 0.9999 221125_WJC_METTL3_EV_vs_WT_F02.16464.16464.2 8.30E-05 16-Oct K.AAVEWFDGK[136.11].D "sp|Q01844|EWS_HUMAN,tr|B0QYK0|B0QYK0_HUMAN,tr|H7BY36|H7BY36_HUMAN,tr|A0A0D9SFL3|A0A0D9SFL3_HUMAN,tr|C9JGE3|C9JGE3_HUMAN" 5 1029.5011 0.67 16130 16464 2 1029.50144 515.7578 RNA-binding protein EWS OS=Homo sapiens OX=9606 GN=EWSR1 PE=1 SV=1 4.37 3092.7 - 1.22E+07 - - - 0.3341 - 2.216 0.464 - 413.3 1 2 0 0.0003 9 0 0 0 6.49E+08 9.62E+08 - - - 4.77 0.9999 221125_WJC_METTL3_EV_vs_WT_F02.16467.16467.2 1.47E-05 14/24 K.VSATAAELAPFPR.G sp|P31260|HXA10_HUMAN 1 1328.7089 1.47 16133 16467 2 1328.709352 665.3617 Homeobox protein Hox-A10 OS=Homo sapiens OX=9606 GN=HOXA10 PE=1 SV=3 5.97 3093 - 709818 - - - 0.3771 - 2.777 0.47 - 431.4 1 2 0 0.0005 13 0 0 0 1.11E+07 7.57E+06 - - - 5.1336 0.9134 221125_WJC_METTL3_EV_vs_WT_F02.16468.16468.2 2.36 12-Jul R.QMSLLLR.R sp|P25705|ATPA_HUMAN 1 859.495 0.71 16134 16468 2 859.497996 430.7548 "ATP synthase subunit alpha, mitochondrial OS=Homo sapiens OX=9606 GN=ATP5F1A PE=1 SV=1" 9.75 3093.1 - 617493 - - - 3.5346 - 1.369 0.05 - 172 1 2 0 0.003 7 0 0 0 7.77E+06 1.09E+07 - - - 0.4045 0.9427 221125_WJC_METTL3_EV_vs_WT_F02.16469.16469.2 4 12-Jul R.LNLYELK.E "sp|P49720|PSB3_HUMAN,tr|A0A087WXQ8|A0A087WXQ8_HUMAN,tr|A0A087WUL2|A0A087WUL2_HUMAN,tr|A0A087WY10|A0A087WY10_HUMAN" 4 891.5066 0.7 16135 16469 2 891.5065 446.7606 Proteasome subunit beta type-3 OS=Homo sapiens OX=9606 GN=PSMB3 PE=1 SV=2 6 3093.2 - 582220 - - - -0.0774 - 1.075 0.027 - 129.2 1 2 0 -0.0001 7 0 0 0 4.85E+06 6.97E+06 - - - -0.5304 0.999 221125_WJC_METTL3_EV_vs_WT_F02.16475.16475.2 0.000523 18-Aug R.EYFGQFGEVK.E sp|O43347|MSI1H_HUMAN 1 1202.5608 1.1 16139 16475 2 1202.557639 602.2877 RNA-binding protein Musashi homolog 1 OS=Homo sapiens OX=9606 GN=MSI1 PE=1 SV=1 4.53 3094 - 1.00E+07 - - - -2.6194 - 1.409 0.487 - 173.7 1 2 0 -0.0032 10 0 0 0 4.48E+08 4.05E+08 - - - 3.5941 0.9977 221125_WJC_METTL3_EV_vs_WT_F02.16476.16476.2 0.0824 14-Jul K.FLVGFTNK.G "sp|P43307|SSRA_HUMAN,tr|A0A3B3IRT8|A0A3B3IRT8_HUMAN,tr|E9PAL7|E9PAL7_HUMAN,tr|C9IZQ1|C9IZQ1_HUMAN,tr|C9J3L8|C9J3L8_HUMAN,tr|C9J5W0|C9J5W0_HUMAN" 6 924.5069 1.22 16140 16476 2 924.5068 463.2607 Translocon-associated protein subunit alpha OS=Homo sapiens OX=9606 GN=SSR1 PE=1 SV=3 8.75 3094 - 4.61E+06 - - - -0.1114 - 1.352 0.233 - 140.9 1 2 0 -0.0001 8 0 0 0 6.19E+07 5.07E+07 - - - 1.6715 0.9998 221125_WJC_METTL3_EV_vs_WT_F02.16477.16477.2 0.00147 20-Oct K.LIEEVMIGEDK[136.11].L "sp|P78371|TCPB_HUMAN,tr|F8VQ14|F8VQ14_HUMAN,tr|F5GWF6|F5GWF6_HUMAN" 3 1282.657 0.47 16141 16477 2 1282.657511 642.3358 T-complex protein 1 subunit beta OS=Homo sapiens OX=9606 GN=CCT2 PE=1 SV=4 4 3094.1 - 6.29E+06 - - - 0.3945 - 2.021 0.46 - 257.7 1 2 0 0.0005 11 0 0 0 8.53E+07 1.82E+08 - - - 4.3418 0.9999 221125_WJC_METTL3_EV_vs_WT_F02.16478.16478.2 1.82E-05 22-Dec K.TLAVSGLGVVGR.D sp|P11388|TOP2A_HUMAN 1 1127.6663 1.04 16142 16478 2 1127.66666 564.8404 DNA topoisomerase 2-alpha OS=Homo sapiens OX=9606 GN=TOP2A PE=1 SV=3 9.41 3094.1 - 3.93E+06 - - - 0.3565 - 2.371 0.511 - 488.4 1 2 0 0.0004 12 0 0 0 5.51E+07 5.29E+07 - - - 5.0866 0.9774 221125_WJC_METTL3_EV_vs_WT_F02.16479.16479.2 0.0681 16-Jul R.FEVIPQSIR.L "sp|Q92544|TM9S4_HUMAN,tr|A0A0C4DFM1|A0A0C4DFM1_HUMAN" 2 1087.6026 1.06 16143 16479 2 1087.609025 544.8086 Transmembrane 9 superfamily member 4 OS=Homo sapiens OX=9606 GN=TM9SF4 PE=1 SV=2 6 3094.2 - 3.44E+06 - - - 5.9121 - 1.506 0.349 - 206.2 1 2 0 0.0064 9 0 0 0 1.43E+08 1.34E+08 - - - 2.8013 0.9997 221125_WJC_METTL3_EV_vs_WT_F02.16480.16480.2 0.00612 14-Aug K.FLVGFTNK[136.11].G "sp|P43307|SSRA_HUMAN,tr|A0A3B3IRT8|A0A3B3IRT8_HUMAN,tr|E9PAL7|E9PAL7_HUMAN,tr|C9IZQ1|C9IZQ1_HUMAN,tr|C9J3L8|C9J3L8_HUMAN,tr|C9J5W0|C9J5W0_HUMAN" 6 932.5211 1.22 16144 16480 2 932.521758 467.2678 Translocon-associated protein subunit alpha OS=Homo sapiens OX=9606 GN=SSR1 PE=1 SV=3 8.75 3094.2 - 3.33E+06 - - - 0.7024 - 1.76 0.409 - 190.4 1 2 0 0.0007 8 0 0 0 6.17E+07 5.06E+07 - - - 3.7666 0.9999 221125_WJC_METTL3_EV_vs_WT_F02.16482.16482.2 7.26E-06 15/22 R.LPDGTSLTQTFR.A "sp|Q04323|UBXN1_HUMAN,tr|A0A087WTZ5|A0A087WTZ5_HUMAN,tr|E9PJ81|E9PJ81_HUMAN,tr|E9PRQ7|E9PRQ7_HUMAN" 4 1334.683 0.83 16146 16482 2 1334.681983 668.3488 UBX domain-containing protein 1 OS=Homo sapiens OX=9606 GN=UBXN1 PE=1 SV=2 5.84 3094.4 - 936201 - - - -0.7845 - 2.294 0.531 - 477.4 1 2 0 -0.001 12 0 0 0 2.09E+07 2.51E+07 - - - 5.1473 0.9999 221125_WJC_METTL3_EV_vs_WT_F02.16484.16484.2 3.05E-06 13/22 K.ILEDTQFVDGYK.Q "sp|Q14C86|GAPD1_HUMAN,tr|B4DGD8|B4DGD8_HUMAN,tr|F8W9S7|F8W9S7_HUMAN,tr|C9IZ08|C9IZ08_HUMAN,tr|C9IZX9|C9IZX9_HUMAN,tr|B0QZ65|B0QZ65_HUMAN" 6 1426.698 0.73 16148 16484 2 1426.698103 714.3563 GTPase-activating protein and VPS9 domain-containing protein 1 OS=Homo sapiens OX=9606 GN=GAPVD1 PE=1 SV=2 4.03 3094.7 - 398019 - - - 0.0645 - 2.414 0.535 - 529.3 1 2 0 0.0001 12 0 0 0 1.23E+07 1.68E+07 - - - 5.3113 0.9995 221125_WJC_METTL3_EV_vs_WT_F02.16487.16487.2 0.0125 16-Jul R.DELTLEGIK.Q "sp|P38919|IF4A3_HUMAN,tr|I3L3H2|I3L3H2_HUMAN" 2 1016.539 999 16149 16487 2 1016.539241 509.2768 Eukaryotic initiation factor 4A-III OS=Homo sapiens OX=9606 GN=EIF4A3 PE=1 SV=4 4.14 3095.1 - 4.05E+06 - - - 0.2459 - 1.564 0.365 - 191.1 1 2 0 0.0003 9 0 0 0 6.30E+07 0.00E+00 - - - 3.0307 0.9978 221125_WJC_METTL3_EV_vs_WT_F02.16488.16488.2 0.00373 18-Sep R.FLDELEDEAK[136.11].A sp|Q9Y2R0|COA3_HUMAN 1 1215.575 1.57 16150 16488 2 1215.571166 608.7948 "Cytochrome c oxidase assembly factor 3 homolog, mitochondrial OS=Homo sapiens OX=9606 GN=COA3 PE=1 SV=1" 3.83 3095.1 - 2.99E+06 - - - -3.1944 - 1.695 0.361 - 151.2 1 2 0 -0.0039 10 0 0 0 4.47E+08 2.85E+08 - - - 3.179 1 221125_WJC_METTL3_EV_vs_WT_F02.16489.16489.2 3.61E-07 16-Oct R.YNFFTGC[160.03]PK.A sp|Q99832|TCPH_HUMAN 1 1132.5012 0.23 16151 16489 2 1132.501128 567.2579 T-complex protein 1 subunit eta OS=Homo sapiens OX=9606 GN=CCT7 PE=1 SV=2 8.2 3095.1 - 3.39E+06 - - - -0.0336 - 2.081 0.629 - 342.3 1 2 0 0 9 0 0 0 5.91E+07 2.52E+08 - - - 5.807 0.9985 221125_WJC_METTL3_EV_vs_WT_F02.16493.16493.2 3.94E-05 13/22 R.WLTIQSGEQPYK.M sp|O43920|NDUS5_HUMAN 1 1448.73 0.76 16155 16493 2 1448.724417 725.3723 NADH dehydrogenase [ubiquinone] iron-sulfur protein 5 OS=Homo sapiens OX=9606 GN=NDUFS5 PE=1 SV=3 6 3095.7 - 496445 - - - -3.8399 - 2.28 0.41 - 585.4 1 2 0 -0.0056 12 0 0 0 6.03E+06 7.92E+06 - - - 4.2361 0.9944 221125_WJC_METTL3_EV_vs_WT_F02.16497.16497.2 0.911 12-Jul K.EIEDLLR.K "sp|Q9P2D1|CHD7_HUMAN,sp|Q9HCK8|CHD8_HUMAN,sp|Q3L8U1|CHD9_HUMAN,sp|P21810|PGS1_HUMAN,tr|H3BTW3|H3BTW3_HUMAN,tr|A0A2R8Y840|A0A2R8Y840_HUMAN,tr|H0YJG4|H0YJG4_HUMAN,tr|A0A2R8YFI9|A0A2R8YFI9_HUMAN" 8 886.476 0.61 16157 16497 2 886.475628 444.2453 Chromodomain-helicase-DNA-binding protein 7 OS=Homo sapiens OX=9606 GN=CHD7 PE=1 SV=3 4.14 3096.2 - 1.28E+06 - - - -0.4163 - 1.325 0.149 - 222.6 1 2 0 -0.0004 7 0 0 0 2.36E+07 3.88E+07 - - - 1.0331 0.985 221125_WJC_METTL3_EV_vs_WT_F02.16500.16500.2 0.000169 14-Oct A.PGFAQMLK.E sp|P50990|TCPQ_HUMAN 1 890.4684 0.3 16160 16500 2 890.469168 446.2415 T-complex protein 1 subunit theta OS=Homo sapiens OX=9606 GN=CCT8 PE=1 SV=4 9.18 3096.4 - 293702 - - - 0.8524 - 1.825 0.433 - 227.4 1 1 0 0.0008 8 0 0 0 9.67E+06 3.19E+07 - - - 4.0532 0.9999 221125_WJC_METTL3_EV_vs_WT_F02.16505.16505.2 3.16E-07 26-Dec R.FVVLETGGEAGITR[166.11].S "sp|Q7Z2W4|ZCCHV_HUMAN,tr|C9J6P4|C9J6P4_HUMAN" 2 1457.7754 0.93 16163 16505 2 1457.776563 729.895 Zinc finger CCCH-type antiviral protein 1 OS=Homo sapiens OX=9606 GN=ZC3HAV1 PE=1 SV=3 4.53 3097.1 - 690050 - - - 0.8225 - 2.459 0.546 - 460.6 1 2 0 0.0012 14 0 0 0 2.22E+07 2.38E+07 - - - 5.3313 0.9824 221125_WJC_METTL3_EV_vs_WT_F02.16506.16506.2 0.544 16-Aug R.ILSLLEGQK[136.11].L "sp|P51648|AL3A2_HUMAN,tr|I3L1M4|I3L1M4_HUMAN,tr|A0A5F9ZHI5|A0A5F9ZHI5_HUMAN,tr|A0A5F9ZI12|A0A5F9ZI12_HUMAN,tr|J3QS00|J3QS00_HUMAN,tr|A0A5F9ZHN9|A0A5F9ZHN9_HUMAN,tr|A0A5K1VW72|A0A5K1VW72_HUMAN,tr|A0A5F9ZGX4|A0A5F9ZGX4_HUMAN,tr|J3QRD1|J3QRD1_HUMAN" 9 1007.6106 1.43 16164 16506 2 1007.60603 504.8126 Aldehyde dehydrogenase family 3 member A2 OS=Homo sapiens OX=9606 GN=ALDH3A2 PE=1 SV=1 6 3097.2 - 686671 - - - -4.5821 - 1.602 0.24 - 143.3 1 2 0 -0.0046 9 0 0 0 4.86E+07 3.39E+07 - - - 2.1755 0.9989 221125_WJC_METTL3_EV_vs_WT_F02.16508.16508.2 0.00539 14-Aug K.GLVFLNGK[136.11].L sp|L0R8F8|MIDUO_HUMAN 1 854.5105 1.05 16166 16508 2 854.509843 428.2625 MIEF1 upstream open reading frame protein OS=Homo sapiens OX=9606 GN=MIEF1 PE=1 SV=1 8.75 3097.4 - 547520 - - - -0.8145 - 1.444 0.306 - 222.8 1 2 0 -0.0007 8 0 0 0 1.01E+08 9.63E+07 - - - 2.409 0.9981 221125_WJC_METTL3_EV_vs_WT_F02.16513.16513.2 0.0221 20-Nov R.GGIVDEGALLR.A "sp|O43175|SERA_HUMAN,tr|A0A286YF78|A0A286YF78_HUMAN,tr|A0A2C9F2M7|A0A2C9F2M7_HUMAN,tr|A0A286YF22|A0A286YF22_HUMAN,tr|A0A286YFL2|A0A286YFL2_HUMAN,tr|A0A286YFA2|A0A286YFA2_HUMAN,tr|A0A286YFM8|A0A286YFM8_HUMAN" 7 1098.6033 1.42 16170 16513 2 1098.605292 550.3089 D-3-phosphoglycerate dehydrogenase OS=Homo sapiens OX=9606 GN=PHGDH PE=1 SV=4 4.37 3098 - 1.72E+07 - - - 1.7923 - 1.833 0.234 - 343.3 1 2 0 0.002 11 0 0 0 4.92E+08 3.46E+08 - - - 2.408 1 221125_WJC_METTL3_EV_vs_WT_F02.16514.16514.2 5.38E-09 20-Dec R.C[160.03]TYLVLDEADR[166.11].M "sp|Q92841|DDX17_HUMAN,tr|A0A5H1ZRQ2|A0A5H1ZRQ2_HUMAN,tr|A0A1X7SBZ2|A0A1X7SBZ2_HUMAN" 3 1363.6317 0.94 16171 16514 2 1363.632385 682.8231 Probable ATP-dependent RNA helicase DDX17 OS=Homo sapiens OX=9606 GN=DDX17 PE=1 SV=2 4.03 3098.1 - 2.30E+06 - - - 0.4759 - 2.581 0.645 - 845.6 1 2 0 0.0006 11 0 0 0 3.36E+07 3.57E+07 - - - 6.3698 0.9993 221125_WJC_METTL3_EV_vs_WT_F02.16515.16515.2 0.122 20-Sep K.SILLTEQALAK.A sp|Q9GZZ8|LACRT_HUMAN 1 1185.6969 999 16172 16515 2 1185.697299 593.8557 Extracellular glycoprotein lacritin OS=Homo sapiens OX=9606 GN=LACRT PE=1 SV=1 5.72 3098.1 - 4.07E+06 - - - 0.3458 - 2.064 0.244 - 221.9 1 2 0 0.0004 11 0 0 0 4.66E+07 0.00E+00 - - - 2.8034 1 221125_WJC_METTL3_EV_vs_WT_F02.16516.16516.2 6.59E-08 13/22 A.PLNVELDPEIQK.V "sp|Q86Y46|K2C73_HUMAN,sp|Q7RTS7|K2C74_HUMAN,sp|Q3SY84|K2C71_HUMAN,sp|P04264|K2C1_HUMAN,tr|F8W1S1|F8W1S1_HUMAN" 5 1393.7453 149.83 16173 16516 2 1393.745255 697.8799 "Keratin, type II cytoskeletal 73 OS=Homo sapiens OX=9606 GN=KRT73 PE=1 SV=1" 4.14 3098.3 - 1.97E+06 - - - -0.0294 - 2.673 0.573 - 580 1 1 0 0 12 0 0 0 4.00E+07 2.67E+05 - - - 5.8601 0.9948 221125_WJC_METTL3_EV_vs_WT_F02.16517.16517.2 0.289 14-Aug K.GLVFLNGK.L sp|L0R8F8|MIDUO_HUMAN 1 846.4963 1.05 16174 16517 2 846.496989 424.2554 MIEF1 upstream open reading frame protein OS=Homo sapiens OX=9606 GN=MIEF1 PE=1 SV=1 8.75 3098.4 - 942636 - - - 0.7679 - 1.451 0.14 - 257.7 1 2 0 0.0006 8 0 0 0 1.01E+08 9.63E+07 - - - 1.1975 1 221125_WJC_METTL3_EV_vs_WT_F02.16518.16518.2 0.000327 14/20 R.FTDEEVDELYR.E "sp|O14950|ML12B_HUMAN,sp|P19105|ML12A_HUMAN,tr|J3QRS3|J3QRS3_HUMAN" 3 1414.6252 1.22 16175 16518 2 1414.623921 708.3199 Myosin regulatory light chain 12B OS=Homo sapiens OX=9606 GN=MYL12B PE=1 SV=2 3.83 3098.5 - 755586 - - - -0.9324 - 2.725 0.549 - 724 1 2 0 -0.0013 11 0 0 0 3.17E+08 2.60E+08 - - - 5.8074 0.9994 221125_WJC_METTL3_EV_vs_WT_F02.16519.16519.3 0.00291 Jul-36 K.MDANVLMHLR[166.11].S sp|Q7Z2T5|TRM1L_HUMAN 1 1208.6034 0.37 16176 16519 3 1208.599581 403.8751 TRMT1-like protein OS=Homo sapiens OX=9606 GN=TRMT1L PE=1 SV=2 6.5 3098.7 - 368993 - - - -3.121 - 1.627 0.433 - 63.8 1 2 0 -0.0038 10 0 0 0 1.28E+06 3.46E+06 - - - 4.788 0.9998 221125_WJC_METTL3_EV_vs_WT_F02.16522.16522.2 0.00349 14-Sep R.TAWVFDDK[136.11].Y "sp|P05198|IF2A_HUMAN,tr|H0YJS4|H0YJS4_HUMAN,tr|G3V4T5|G3V4T5_HUMAN" 3 988.4745 1.65 16178 16522 2 988.474567 495.2445 Eukaryotic translation initiation factor 2 subunit 1 OS=Homo sapiens OX=9606 GN=EIF2S1 PE=1 SV=3 4.21 3099 - 6.23E+06 - - - 0.0202 - 1.754 0.442 - 376.4 1 2 0 0 8 0 0 0 1.68E+08 1.02E+08 - - - 4.0003 0.9996 221125_WJC_METTL3_EV_vs_WT_F02.16524.16524.2 0.00244 18-Nov R.FLDELEDEAK.A sp|Q9Y2R0|COA3_HUMAN 1 1207.5608 1.57 16179 16524 2 1207.56249 604.7877 "Cytochrome c oxidase assembly factor 3 homolog, mitochondrial OS=Homo sapiens OX=9606 GN=COA3 PE=1 SV=1" 3.83 3099.2 - 3.04E+07 - - - 1.3589 - 2.01 0.378 - 304.9 1 2 0 0.0016 10 0 0 0 4.47E+08 2.85E+08 - - - 3.7811 0.9996 221125_WJC_METTL3_EV_vs_WT_F02.16525.16525.2 0.051 16-Sep R.YATLPNIMK.A "sp|P38117|ETFB_HUMAN,tr|M0QY67|M0QY67_HUMAN" 2 1049.558 6.7 16180 16525 2 1049.55799 525.7863 Electron transfer flavoprotein subunit beta OS=Homo sapiens OX=9606 GN=ETFB PE=1 SV=3 8.59 3099.3 - 5.26E+06 - - - 0.0353 - 1.696 0.375 - 244 1 2 0 0 9 0 0 0 1.04E+08 1.56E+07 - - - 3.3391 0.9798 221125_WJC_METTL3_EV_vs_WT_F02.16526.16526.2 1.35 16-Jun K.LQDAINILK[136.11].E "sp|P42704|LPPRC_HUMAN,tr|A0A804HI14|A0A804HI14_HUMAN,tr|A0A804HL40|A0A804HL40_HUMAN,tr|A0A804HKJ0|A0A804HKJ0_HUMAN,tr|A0A804HKR3|A0A804HKR3_HUMAN,tr|A0A804HIN4|A0A804HIN4_HUMAN,tr|A0A804HLG8|A0A804HLG8_HUMAN,tr|A0A804HHY9|A0A804HHY9_HUMAN,tr|A0A804HJH8|A0A804HJH8_HUMAN,tr|B8ZZ38|B8ZZ38_HUMAN,tr|A0A804HI40|A0A804HI40_HUMAN,tr|C9JCA9|C9JCA9_HUMAN,tr|A0A804HIQ7|A0A804HIQ7_HUMAN,tr|A0A804HK30|A0A804HK30_HUMAN,tr|A0A804HKI2|A0A804HKI2_HUMAN,tr|A0A804HJI0|A0A804HJI0_HUMAN,tr|A0A804HIG4|A0A804HIG4_HUMAN,tr|A0A804HK02|A0A804HK02_HUMAN" 18 1034.6215 0.53 16181 16526 2 1034.620451 518.318 "Leucine-rich PPR motif-containing protein, mitochondrial OS=Homo sapiens OX=9606 GN=LRPPRC PE=1 SV=3" 5.84 3099.3 - 2.01E+06 - - - -1.0584 - 1.251 0.117 - 61.9 4 2 0 -0.0011 9 0 0 0 4.16E+07 7.81E+07 - - - 0.2838 0.99 221125_WJC_METTL3_EV_vs_WT_F02.16528.16528.2 0.00072 20-Dec N.LAIWDTAGQER.F "sp|Q9UL25|RAB21_HUMAN,sp|Q9NP72|RAB18_HUMAN,tr|A0A804HIB9|A0A804HIB9_HUMAN,tr|B7Z4P9|B7Z4P9_HUMAN" 4 1258.6306 1.21 16183 16528 2 1258.631527 630.3226 Ras-related protein Rab-21 OS=Homo sapiens OX=9606 GN=RAB21 PE=1 SV=3 4.37 3099.5 - 1.41E+06 - - - 0.7365 - 2.646 0.394 - 733.8 1 1 0 0.0009 11 0 0 0 2.17E+07 1.80E+07 - - - 4.5831 0.9996 221125_WJC_METTL3_EV_vs_WT_F02.16529.16529.2 0.0966 16-Nov R.ILSLLEGQK.L "sp|P51648|AL3A2_HUMAN,tr|I3L1M4|I3L1M4_HUMAN,tr|A0A5F9ZHI5|A0A5F9ZHI5_HUMAN,tr|A0A5F9ZI12|A0A5F9ZI12_HUMAN,tr|J3QS00|J3QS00_HUMAN,tr|A0A5F9ZHN9|A0A5F9ZHN9_HUMAN,tr|A0A5K1VW72|A0A5K1VW72_HUMAN,tr|A0A5F9ZGX4|A0A5F9ZGX4_HUMAN,tr|J3QRD1|J3QRD1_HUMAN" 9 999.5964 1.45 16184 16529 2 999.597125 500.8055 Aldehyde dehydrogenase family 3 member A2 OS=Homo sapiens OX=9606 GN=ALDH3A2 PE=1 SV=1 6 3099.6 - 1.21E+06 - - - 0.6783 - 2.074 0.313 - 281.7 1 2 0 0.0007 9 0 0 0 4.93E+07 3.39E+07 - - - 3.463 0.8186 221125_WJC_METTL3_EV_vs_WT_F02.16530.16530.2 0.00313 20-Nov N.LAIWDTAGQER[166.11].F "sp|Q9UL25|RAB21_HUMAN,sp|Q9NP72|RAB18_HUMAN,tr|A0A804HIB9|A0A804HIB9_HUMAN,tr|B7Z4P9|B7Z4P9_HUMAN" 4 1268.6389 1.21 16185 16530 2 1268.634113 635.3267 Ras-related protein Rab-21 OS=Homo sapiens OX=9606 GN=RAB21 PE=1 SV=3 4.37 3099.6 - 1.11E+06 - - - -3.7497 - 1.999 0.293 - 487.8 1 1 0 -0.0048 11 0 0 0 2.17E+07 1.80E+07 - - - 3.0774 0.9997 221125_WJC_METTL3_EV_vs_WT_F02.16535.16535.2 0.00396 22-Dec K.GILLYGPPGC[160.03]GK.T "sp|P46459|NSF_HUMAN,tr|I3L0N3|I3L0N3_HUMAN" 2 1230.6431 1.26 16189 16535 2 1230.641864 616.3288 Vesicle-fusing ATPase OS=Homo sapiens OX=9606 GN=NSF PE=1 SV=3 8.2 3100.3 - 814056 - - - -0.9881 - 2.04 0.383 - 316.7 1 2 0 -0.0012 12 0 0 0 1.94E+07 1.54E+07 - - - 3.7453 0.9998 221125_WJC_METTL3_EV_vs_WT_F02.16537.16537.2 0.00211 16-Nov K.MDQAIIFC[160.03]R[166.11].T "sp|Q92499|DDX1_HUMAN,tr|A0A7I2V2M5|A0A7I2V2M5_HUMAN,tr|A0A087X2G1|A0A087X2G1_HUMAN,tr|A0A7I2V430|A0A7I2V430_HUMAN,tr|A0A7I2V4F0|A0A7I2V4F0_HUMAN,tr|A0A087WZ71|A0A087WZ71_HUMAN,tr|A0A7I2YQ77|A0A7I2YQ77_HUMAN" 7 1162.5503 1.17 16190 16537 2 1162.549829 582.2824 ATP-dependent RNA helicase DDX1 OS=Homo sapiens OX=9606 GN=DDX1 PE=1 SV=2 5.59 3100.5 - 1.30E+06 - - - -0.3664 - 2.374 0.393 - 552.7 1 2 0 -0.0004 9 0 0 0 2.71E+07 2.32E+07 - - - 4.4448 0.9998 221125_WJC_METTL3_EV_vs_WT_F02.16538.16538.2 0.000438 18-Sep K.FSTWTNTEFR.Y sp|P07099|HYEP_HUMAN 1 1287.5884 1.42 16191 16538 2 1287.589885 644.8015 Epoxide hydrolase 1 OS=Homo sapiens OX=9606 GN=EPHX1 PE=1 SV=1 6 3100.5 - 1.35E+06 - - - 1.1525 - 1.788 0.523 - 305.2 1 2 0 0.0015 10 0 0 0 1.70E+07 1.19E+07 - - - 4.5254 1 221125_WJC_METTL3_EV_vs_WT_F02.16539.16539.2 2.52E-06 13/20 R.FTDEEVDELYR[166.11].E "sp|O14950|ML12B_HUMAN,sp|P19105|ML12A_HUMAN,tr|J3QRS3|J3QRS3_HUMAN" 3 1424.6335 1.22 16192 16539 2 1424.634155 713.324 Myosin regulatory light chain 12B OS=Homo sapiens OX=9606 GN=MYL12B PE=1 SV=2 3.83 3100.6 - 3.72E+06 - - - 0.4527 - 2.685 0.618 - 594.8 1 2 0 0.0006 11 0 0 0 3.17E+08 2.60E+08 - - - 6.2773 0.9998 221125_WJC_METTL3_EV_vs_WT_F02.16540.16540.2 0.000181 20-Dec R.LSVEADINGLR.R "sp|Q04695|K1C17_HUMAN,tr|F5GWP8|F5GWP8_HUMAN" 2 1185.6354 55.8 16193 16540 2 1185.636931 593.825 "Keratin, type I cytoskeletal 17 OS=Homo sapiens OX=9606 GN=KRT17 PE=1 SV=2" 4.37 3100.6 - 3.54E+06 - - - 1.3326 - 2.39 0.47 - 624.7 1 2 0 0.0016 11 0 0 0 1.95E+08 3.49E+06 - - - 4.869 0.9997 221125_WJC_METTL3_EV_vs_WT_F02.16542.16542.2 0.00175 18-Nov K.FSTWTNTEFR[166.11].Y sp|P07099|HYEP_HUMAN 1 1297.5967 1.4 16195 16542 2 1297.596098 649.8056 Epoxide hydrolase 1 OS=Homo sapiens OX=9606 GN=EPHX1 PE=1 SV=1 6 3100.9 - 1.04E+06 - - - -0.4416 - 1.861 0.399 - 497 1 2 0 -0.0006 10 0 0 0 1.67E+07 1.19E+07 - - - 3.7216 0.9999 221125_WJC_METTL3_EV_vs_WT_F02.16543.16543.2 1.82E-06 24-Nov K.VISGTTLGYLSPK[136.11].D "sp|Q9NUL3|STAU2_HUMAN,tr|E5RJN7|E5RJN7_HUMAN,tr|E7EVJ4|E7EVJ4_HUMAN,tr|E7EPX0|E7EPX0_HUMAN,tr|H0YBY0|H0YBY0_HUMAN,tr|E5RJ67|E5RJ67_HUMAN" 6 1342.7588 1.3 16196 16543 2 1342.758826 672.3867 Double-stranded RNA-binding protein Staufen homolog 2 OS=Homo sapiens OX=9606 GN=STAU2 PE=1 SV=2 8.56 3101 - 1.02E+06 - - - 0.0432 - 2.183 0.565 - 240.3 1 2 0 0.0001 13 0 0 0 1.89E+07 1.45E+07 - - - 5.2178 0.9997 221125_WJC_METTL3_EV_vs_WT_F02.16544.16544.2 9.66E-05 18-Nov K.IC[160.03]SWNVDGLR[166.11].A "sp|P27695|APEX1_HUMAN,tr|G3V3C7|G3V3C7_HUMAN,tr|G3V5D9|G3V5D9_HUMAN,tr|G3V5M0|G3V5M0_HUMAN,tr|G3V3M6|G3V3M6_HUMAN,tr|H7C4A8|H7C4A8_HUMAN,tr|A0A0C4DGK8|A0A0C4DGK8_HUMAN,tr|G3V359|G3V359_HUMAN,tr|G3V5Q1|G3V5Q1_HUMAN" 9 1228.5898 2.06 16197 16544 2 1228.588575 615.3022 DNA-(apurinic or apyrimidinic site) endonuclease OS=Homo sapiens OX=9606 GN=APEX1 PE=1 SV=2 5.83 3101.1 - 954872 - - - -1.0068 - 2.09 0.383 - 340.2 1 2 0 -0.0012 10 0 0 0 4.66E+07 2.26E+07 - - - 3.9271 0.999 221125_WJC_METTL3_EV_vs_WT_F02.16545.16545.2 0.00316 22-Aug R.EEIIPVAAEYDK.T "sp|P11310|ACADM_HUMAN,tr|A0A7P0TB28|A0A7P0TB28_HUMAN,tr|A0A7P0TB51|A0A7P0TB51_HUMAN,tr|E9PJM9|E9PJM9_HUMAN,tr|Q5T4U5|Q5T4U5_HUMAN,tr|E9PRX4|E9PRX4_HUMAN,tr|A0A7P0TA63|A0A7P0TA63_HUMAN,tr|A0A7P0TBD1|A0A7P0TBD1_HUMAN,tr|A0A7P0T8J9|A0A7P0T8J9_HUMAN,tr|F6YB23|F6YB23_HUMAN,tr|A0A7P0TA39|A0A7P0TA39_HUMAN,tr|A0A7P0T932|A0A7P0T932_HUMAN,tr|A0A7P0T9W7|A0A7P0T9W7_HUMAN,tr|A0A7P0TAB2|A0A7P0TAB2_HUMAN" 14 1375.6871 0.06 16198 16545 2 1375.6884 688.8508 "Medium-chain specific acyl-CoA dehydrogenase, mitochondrial OS=Homo sapiens OX=9606 GN=ACADM PE=1 SV=1" 4 3101.2 - 555385 - - - 0.9363 - 1.595 0.32 - 190.1 1 2 0 0.0013 12 0 0 0 5.46E+06 9.59E+07 - - - 2.6325 0.9917 221125_WJC_METTL3_EV_vs_WT_F02.16547.16547.2 0.0426 26-Dec M.VLFADQATPTSPIR.V "sp|P21333|FLNA_HUMAN,tr|A0A7P0NMY4|A0A7P0NMY4_HUMAN,tr|Q60FE5|Q60FE5_HUMAN" 3 1514.8093 1.78 16200 16547 2 1514.80985 758.4119 Filamin-A OS=Homo sapiens OX=9606 GN=FLNA PE=1 SV=4 5.81 3101.5 - 378306 - - - 0.3677 - 2.416 0.466 - 384.8 1 1 0 0.0006 14 0 0 0 7.49E+06 4.21E+06 - - - 4.6963 0.9882 221125_WJC_METTL3_EV_vs_WT_F02.16548.16548.2 0.149 12-Aug K.WTWSAVR.G "sp|O75410|TACC1_HUMAN,tr|E5RJG6|E5RJG6_HUMAN" 2 904.4555 1.07 16201 16548 2 904.458332 453.235 Transforming acidic coiled-coil-containing protein 1 OS=Homo sapiens OX=9606 GN=TACC1 PE=1 SV=2 9.75 3101.6 - 352600 - - - 3.0914 - 1.575 0.157 - 289.9 1 2 0 0.0028 7 0 0 0 8.73E+07 8.14E+07 - - - 1.6391 0.9999 221125_WJC_METTL3_EV_vs_WT_F02.16551.16551.2 0.00158 20-Aug K.LIEEVMIGEDK.L "sp|P78371|TCPB_HUMAN,tr|F8VQ14|F8VQ14_HUMAN,tr|F5GWF6|F5GWF6_HUMAN" 3 1274.6428 0.47 16203 16551 2 1274.642812 638.3287 T-complex protein 1 subunit beta OS=Homo sapiens OX=9606 GN=CCT2 PE=1 SV=4 4 3102 - 1.74E+06 - - - 0.0055 - 1.876 0.509 - 176.1 1 2 0 0 11 0 0 0 8.53E+07 1.81E+08 - - - 4.5024 0.9998 221125_WJC_METTL3_EV_vs_WT_F02.16552.16552.2 6.66E-05 22-Oct K.FAQALGLTEAVK.V "sp|P78347|GTF2I_HUMAN,tr|A0A494C1K3|A0A494C1K3_HUMAN" 2 1246.6921 2.05 16204 16552 2 1246.692688 624.3533 General transcription factor II-I OS=Homo sapiens OX=9606 GN=GTF2I PE=1 SV=2 6 3102.1 - 591291 - - - 0.4412 - 1.91 0.473 - 240.6 1 2 0 0.0006 12 0 0 0 3.95E+07 1.93E+07 - - - 4.237 0.9861 221125_WJC_METTL3_EV_vs_WT_F02.16553.16553.2 0.000106 22-Sep R.AFSTVPLTPVPR.P "sp|Q9ULV3|CIZ1_HUMAN,tr|Q5SYW2|Q5SYW2_HUMAN,tr|F5H2X7|F5H2X7_HUMAN,tr|H0Y5D5|H0Y5D5_HUMAN,tr|A0A494C0L7|A0A494C0L7_HUMAN,tr|Q9BTG3|Q9BTG3_HUMAN" 6 1283.7238 2.97 16205 16553 2 1283.723721 642.8692 Cip1-interacting zinc finger protein OS=Homo sapiens OX=9606 GN=CIZ1 PE=1 SV=2 9.79 3102.1 - 3.98E+06 - - - -0.0397 - 1.549 0.498 - 160 1 1 0 -0.0001 12 0 0 0 2.73E+08 9.19E+07 - - - 3.8706 0.9928 221125_WJC_METTL3_EV_vs_WT_F02.16554.16554.2 5.35E-06 22-Nov R.AFSTVPLTPVPR[166.11].P "sp|Q9ULV3|CIZ1_HUMAN,tr|Q5SYW2|Q5SYW2_HUMAN,tr|F5H2X7|F5H2X7_HUMAN,tr|H0Y5D5|H0Y5D5_HUMAN,tr|A0A494C0L7|A0A494C0L7_HUMAN,tr|Q9BTG3|Q9BTG3_HUMAN" 6 1293.732 2.97 16206 16554 2 1293.731532 647.8733 Cip1-interacting zinc finger protein OS=Homo sapiens OX=9606 GN=CIZ1 PE=1 SV=2 9.79 3102.2 - 1.94E+06 - - - -0.3942 - 2.088 0.529 - 248.3 1 1 0 -0.0005 12 0 0 0 2.72E+08 9.17E+07 - - - 4.8851 0.9996 221125_WJC_METTL3_EV_vs_WT_F02.16555.16555.2 0.00681 18-Sep R.SDVFPGPSFR.S "sp|Q8IX01|SUGP2_HUMAN,tr|M0R216|M0R216_HUMAN,tr|M0R065|M0R065_HUMAN,tr|M0R2Z9|M0R2Z9_HUMAN,tr|M0R3F6|M0R3F6_HUMAN" 5 1107.5349 0.59 16207 16555 2 1107.535242 554.7747 SURP and G-patch domain-containing protein 2 OS=Homo sapiens OX=9606 GN=SUGP2 PE=1 SV=2 5.55 3102.3 - 1.87E+06 - - - 0.3007 - 1.63 0.377 - 263.5 1 2 0 0.0003 10 0 0 0 3.17E+07 5.38E+07 - - - 3.1892 0.9997 221125_WJC_METTL3_EV_vs_WT_F02.16558.16558.2 0.0249 22-Dec K.ALPLEAEVAPVK[136.11].D "sp|P27816|MAP4_HUMAN,tr|E7EVA0|E7EVA0_HUMAN,tr|A0A804HKE7|A0A804HKE7_HUMAN" 3 1243.7267 0.8 16210 16558 2 1243.725478 622.8706 Microtubule-associated protein 4 OS=Homo sapiens OX=9606 GN=MAP4 PE=1 SV=3 4.53 3102.6 - 591291 - - - -1.0139 - 2.054 0.376 - 389.7 1 2 0 -0.0013 12 0 0 0 9.24E+06 1.16E+07 - - - 3.7116 0.997 221125_WJC_METTL3_EV_vs_WT_F02.16559.16559.2 0.0964 12-Aug K.QFLC[160.03]IPR.R "sp|Q9H089|LSG1_HUMAN,tr|F8WFC6|F8WFC6_HUMAN" 2 932.4902 0.09 16211 16559 2 932.492261 467.2524 Large subunit GTPase 1 homolog OS=Homo sapiens OX=9606 GN=LSG1 PE=1 SV=2 8.25 3102.7 - 752378 - - - 2.2016 - 1.581 0.238 - 270.9 1 2 0 0.0021 7 0 0 0 7.68E+06 8.33E+07 - - - 2.2496 1 221125_WJC_METTL3_EV_vs_WT_F02.16561.16561.2 6.04E-08 14/26 R.FVVLETGGEAGITR.S "sp|Q7Z2W4|ZCCHV_HUMAN,tr|C9J6P4|C9J6P4_HUMAN" 2 1447.7671 0.93 16212 16561 2 1447.766103 724.8908 Zinc finger CCCH-type antiviral protein 1 OS=Homo sapiens OX=9606 GN=ZC3HAV1 PE=1 SV=3 4.53 3102.9 - 1.65E+06 - - - -0.6845 - 2.753 0.64 - 660.8 1 2 0 -0.001 14 0 0 0 2.22E+07 2.38E+07 - - - 6.309 0.9999 221125_WJC_METTL3_EV_vs_WT_F02.16562.16562.2 2.65E-08 20-Dec R.C[160.03]TYLVLDEADR.M "sp|Q92841|DDX17_HUMAN,tr|A0A5H1ZRQ2|A0A5H1ZRQ2_HUMAN,tr|A0A1X7SBZ2|A0A1X7SBZ2_HUMAN" 3 1353.6235 0.94 16213 16562 2 1353.623057 677.819 Probable ATP-dependent RNA helicase DDX17 OS=Homo sapiens OX=9606 GN=DDX17 PE=1 SV=2 4.03 3103 - 1.13E+06 - - - -0.3022 - 2.398 0.567 - 700.9 1 2 0 -0.0004 11 0 0 0 3.36E+07 3.57E+07 - - - 5.5948 0.9985 221125_WJC_METTL3_EV_vs_WT_F02.16563.16563.2 0.0892 20-Aug K.LLLLGTGESGK[136.11].S "sp|O95837|GNA14_HUMAN,sp|P50148|GNAQ_HUMAN,sp|P29992|GNA11_HUMAN" 3 1094.6427 1.12 16214 16563 2 1094.641805 548.3286 Guanine nucleotide-binding protein subunit alpha-14 OS=Homo sapiens OX=9606 GN=GNA14 PE=1 SV=1 6 3103.1 - 1.88E+06 - - - -0.7948 - 1.788 0.206 - 165.6 1 2 0 -0.0009 11 0 0 0 2.55E+07 2.27E+07 - - - 2.1342 0.9995 221125_WJC_METTL3_EV_vs_WT_F02.16564.16564.2 0.000146 20-Oct R.IYVGNLPPDIR.T "sp|Q07955|SRSF1_HUMAN,tr|J3QQV5|J3QQV5_HUMAN,tr|J3KTL2|J3KTL2_HUMAN,tr|J3KSW7|J3KSW7_HUMAN" 4 1255.6925 2.36 16215 16564 2 1255.694762 628.8535 Serine\arginine-rich splicing factor 1 OS=Homo sapiens OX=9606 GN=SRSF1 PE=1 SV=2 5.84 3103.2 - 1.51E+06 - - - 1.8237 - 1.959 0.412 - 330.8 1 2 0 0.0023 11 0 0 0 4.11E+07 1.74E+07 - - - 3.9024 0.9997 221125_WJC_METTL3_EV_vs_WT_F02.16565.16565.2 0.00178 16-Oct R.ALQALEELR.L sp|Q15149|PLEC_HUMAN 1 1041.5819 2.1 16216 16565 2 1041.580696 521.7982 Plectin OS=Homo sapiens OX=9606 GN=PLEC PE=1 SV=3 4.53 3103.3 - 1.45E+06 - - - -1.1166 - 2.104 0.383 - 367.1 1 2 0 -0.0012 9 0 0 0 3.79E+07 1.81E+07 - - - 4.0214 0.9998 221125_WJC_METTL3_EV_vs_WT_F02.16568.16568.2 2.72E-05 20-Oct R.IYVGNLPPDIR[166.11].T "sp|Q07955|SRSF1_HUMAN,tr|J3QQV5|J3QQV5_HUMAN,tr|J3KTL2|J3KTL2_HUMAN,tr|J3KSW7|J3KSW7_HUMAN" 4 1265.7007 2.36 16219 16568 2 1265.702393 633.8576 Serine\arginine-rich splicing factor 1 OS=Homo sapiens OX=9606 GN=SRSF1 PE=1 SV=2 5.84 3103.7 - 978751 - - - 1.3044 - 2.264 0.475 - 311 1 2 0 0.0017 11 0 0 0 4.11E+07 1.74E+07 - - - 4.7594 0.9999 221125_WJC_METTL3_EV_vs_WT_F02.16569.16569.2 1.83E-06 13/22 R.WTELAGC[160.03]TADFR[166.11].N "sp|Q12907|LMAN2_HUMAN,tr|D6RBV2|D6RBV2_HUMAN,tr|D6RDX1|D6RDX1_HUMAN,tr|D6RIU4|D6RIU4_HUMAN" 4 1435.643 24.83 16220 16569 2 1435.641009 718.8288 Vesicular integral-membrane protein VIP36 OS=Homo sapiens OX=9606 GN=LMAN2 PE=1 SV=1 4.37 3103.8 - 801080 - - - -1.3659 - 2.266 0.589 - 600.8 1 2 0 -0.002 12 0 0 0 1.94E+08 7.81E+06 - - - 5.5431 0.9994 221125_WJC_METTL3_EV_vs_WT_F02.16570.16570.2 0.0113 14-Aug K.AALEQLLK[136.11].F "sp|Q92797|SYMPK_HUMAN,tr|A0A087WUE9|A0A087WUE9_HUMAN,tr|M0R3C7|M0R3C7_HUMAN" 3 892.5473 0.74 16221 16570 2 892.546243 447.2809 Symplekin OS=Homo sapiens OX=9606 GN=SYMPK PE=1 SV=2 6.05 3104 - 784602 - - - -1.2044 - 1.727 0.32 - 182 1 2 0 -0.0011 8 0 0 0 5.18E+06 6.99E+06 - - - 3.0521 0.9999 221125_WJC_METTL3_EV_vs_WT_F02.16574.16574.2 4.25E-06 20-Dec R.VFSGLVSTGLK.V sp|P13639|EF2_HUMAN 1 1106.6336 0.48 16223 16574 2 1106.634222 554.3241 Elongation factor 2 OS=Homo sapiens OX=9606 GN=EEF2 PE=1 SV=4 8.72 3104.5 - 2.78E+06 - - - 0.5982 - 2.162 0.547 - 353.8 1 2 0 0.0007 11 0 0 0 1.93E+08 4.01E+08 - - - 5.1668 0.9988 221125_WJC_METTL3_EV_vs_WT_F02.16577.16577.2 0.284 16-Sep R.LQIEDFEAR.L "sp|Q9P0J0|NDUAD_HUMAN,tr|B4DEZ3|B4DEZ3_HUMAN,tr|E7ENQ6|E7ENQ6_HUMAN,tr|K7EJE1|K7EJE1_HUMAN,tr|U3KQP3|U3KQP3_HUMAN" 5 1119.556 1.64 16226 16577 2 1119.554651 560.7853 NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 13 OS=Homo sapiens OX=9606 GN=NDUFA13 PE=1 SV=3 4.14 3104.6 - 1.84E+06 - - - -1.2389 - 1.769 0.245 - 298.1 1 2 0 -0.0014 9 0 0 0 5.06E+07 3.08E+07 - - - 2.5004 0.9993 221125_WJC_METTL3_EV_vs_WT_F02.16579.16579.2 0.000901 16-Aug K.ELGVGIALR.K sp|Q01469|FABP5_HUMAN 1 926.5549 16.41 16228 16579 2 926.554707 464.2847 Fatty acid-binding protein 5 OS=Homo sapiens OX=9606 GN=FABP5 PE=1 SV=3 6.1 3104.9 - 1.16E+06 - - - -0.2256 - 1.666 0.297 - 195.2 1 2 0 -0.0002 9 0 0 0 1.57E+07 9.54E+05 - - - 2.7113 0.9989 221125_WJC_METTL3_EV_vs_WT_F02.16580.16580.2 0.26 12-Jul R.FPNLQLR[166.11].D "sp|Q8TB72|PUM2_HUMAN,tr|A0A0C4DG68|A0A0C4DG68_HUMAN" 2 896.5108 1.41 16229 16580 2 896.510718 449.2627 Pumilio homolog 2 OS=Homo sapiens OX=9606 GN=PUM2 PE=1 SV=2 9.75 3105 - 989576 - - - -0.0435 - 1.698 0.211 - 223.7 1 2 0 0 7 0 0 0 1.10E+08 7.81E+07 - - - 2.277 0.9995 221125_WJC_METTL3_EV_vs_WT_F02.16581.16581.2 0.0036 18-Oct R.FLTFDSPEGK.A "sp|Q9BW92|SYTM_HUMAN,tr|U3KQ50|U3KQ50_HUMAN,tr|U3KQG0|U3KQG0_HUMAN" 3 1139.5499 0.61 16230 16581 2 1139.547086 570.7822 "Threonine--tRNA ligase, mitochondrial OS=Homo sapiens OX=9606 GN=TARS2 PE=1 SV=1" 4.37 3105.1 - 760828 - - - -2.4606 - 1.825 0.475 - 267.8 1 2 0 -0.0028 10 0 0 0 1.03E+07 1.68E+07 - - - 4.2277 0.9925 221125_WJC_METTL3_EV_vs_WT_F02.16583.16583.2 0.000709 26-Oct M.VLFADQATPTSPIR[166.11].V "sp|P21333|FLNA_HUMAN,tr|A0A7P0NMY4|A0A7P0NMY4_HUMAN,tr|Q60FE5|Q60FE5_HUMAN" 3 1524.8176 1.78 16232 16583 2 1524.818637 763.4161 Filamin-A OS=Homo sapiens OX=9606 GN=FLNA PE=1 SV=4 5.81 3105.4 - 345241 - - - 0.7043 - 2.306 0.533 - 311.3 1 1 0 0.0011 14 0 0 0 7.49E+06 4.21E+06 - - - 5.0741 0.9993 221125_WJC_METTL3_EV_vs_WT_F02.16587.16587.2 0.00407 16-Sep K.LQVALGELR.R sp|P19474|RO52_HUMAN 1 997.592 1.78 16234 16587 2 997.591728 499.8033 E3 ubiquitin-protein ligase TRIM21 OS=Homo sapiens OX=9606 GN=TRIM21 PE=1 SV=1 6 3105.8 - 4.04E+06 - - - -0.3027 - 1.915 0.236 - 323 1 2 0 -0.0003 9 0 0 0 1.48E+08 8.29E+07 - - - 2.6637 0.9996 221125_WJC_METTL3_EV_vs_WT_F02.16588.16588.2 0.000612 20-Nov R.IIIQESALDYR.L sp|Q92896|GSLG1_HUMAN 1 1319.7085 1.57 16235 16588 2 1319.711029 660.8615 Golgi apparatus protein 1 OS=Homo sapiens OX=9606 GN=GLG1 PE=1 SV=2 4.37 3105.9 - 2.77E+06 - - - 1.9042 - 1.961 0.439 - 476.8 1 2 0 0.0025 11 0 0 0 4.49E+07 2.87E+07 - - - 4.1045 0.9993 221125_WJC_METTL3_EV_vs_WT_F02.16589.16589.2 0.00167 16-Nov K.TPEIYLAYR[166.11].N "sp|Q8TAQ2|SMRC2_HUMAN,sp|Q92922|SMRC1_HUMAN,tr|F8VXC8|F8VXC8_HUMAN" 3 1134.5949 2.07 16236 16589 2 1134.591255 568.3047 SWI\SNF complex subunit SMARCC2 OS=Homo sapiens OX=9606 GN=SMARCC2 PE=1 SV=1 5.66 3105.9 - 1.43E+06 - - - -3.195 - 2.349 0.434 - 673.4 1 2 0 -0.0036 9 0 0 0 6.16E+07 2.97E+07 - - - 4.716 0.9999 221125_WJC_METTL3_EV_vs_WT_F02.16593.16593.2 3.25E-05 22-Nov R.IMNVIGEPIDER.G "sp|P06576|ATPB_HUMAN,tr|F8W079|F8W079_HUMAN,tr|H0YH81|H0YH81_HUMAN" 3 1384.7021 1.97 16240 16593 2 1384.702157 693.3583 "ATP synthase subunit beta, mitochondrial OS=Homo sapiens OX=9606 GN=ATP5F1B PE=1 SV=3" 4.14 3106.4 - 498711 - - - 0.0766 - 2.528 0.491 - 548.1 1 2 0 0.0001 12 0 0 0 4.82E+08 2.44E+08 - - - 5.1077 0.9998 221125_WJC_METTL3_EV_vs_WT_F02.16596.16596.2 0.000816 20-Dec K.LSILYPATTGR.N sp|P30041|PRDX6_HUMAN 1 1190.6659 0.89 16241 16596 2 1190.664772 596.3402 Peroxiredoxin-6 OS=Homo sapiens OX=9606 GN=PRDX6 PE=1 SV=3 8.75 3106.8 - 1.99E+06 - - - -0.9667 - 2.508 0.406 - 424.2 1 2 0 -0.0012 11 0 0 0 7.62E+07 8.52E+07 - - - 4.5268 0.9994 221125_WJC_METTL3_EV_vs_WT_F02.16602.16602.2 0.0162 20-Sep K.AILILDNDGDR.L "sp|P61923|COPZ1_HUMAN,tr|F8VVA7|F8VVA7_HUMAN,tr|F8W651|F8W651_HUMAN,tr|F8W156|F8W156_HUMAN,tr|F8VYZ4|F8VYZ4_HUMAN,tr|F8VUC5|F8VUC5_HUMAN,tr|F8VXB1|F8VXB1_HUMAN,tr|F8VXR1|F8VXR1_HUMAN" 8 1213.6303 999 16245 16602 2 1213.630349 607.8224 Coatomer subunit zeta-1 OS=Homo sapiens OX=9606 GN=COPZ1 PE=1 SV=1 3.93 3107.5 - 1.84E+06 - - - 0.0684 - 1.989 0.253 - 241.9 1 2 0 0.0001 11 0 0 0 5.22E+07 0.00E+00 - - - 2.7698 0.9997 221125_WJC_METTL3_EV_vs_WT_F02.16603.16603.2 0.00354 18-Oct R.ILSYMGELQR[166.11].R sp|Q9BST9|RTKN_HUMAN 1 1218.6306 0.68 16246 16603 2 1218.631106 610.3226 Rhotekin OS=Homo sapiens OX=9606 GN=RTKN PE=1 SV=2 6 3107.7 - 979887 - - - 0.4037 - 1.758 0.39 - 256.8 1 2 0 0.0005 10 0 0 0 1.02E+07 1.51E+07 - - - 3.4962 0.9987 221125_WJC_METTL3_EV_vs_WT_F02.16605.16605.2 0.0063 14-Aug K.NVPYVFVR.S "sp|P55769|NH2L1_HUMAN,tr|B1AHD1|B1AHD1_HUMAN,tr|A0A3B3ISH1|A0A3B3ISH1_HUMAN,tr|A0A3B3IUA2|A0A3B3IUA2_HUMAN,tr|A0A3B3IRU2|A0A3B3IRU2_HUMAN" 5 992.5444 2.15 16248 16605 2 992.544129 497.2795 NHP2-like protein 1 OS=Homo sapiens OX=9606 GN=SNU13 PE=1 SV=3 8.75 3107.9 - 516343 - - - -0.2237 - 1.301 0.312 - 246.9 1 2 0 -0.0002 8 0 0 0 1.07E+07 4.96E+06 - - - 2.139 0.9826 221125_WJC_METTL3_EV_vs_WT_F02.16606.16606.2 0.00239 24-Dec K.VISGTTLGYLSPK.D "sp|Q9NUL3|STAU2_HUMAN,tr|E5RJN7|E5RJN7_HUMAN,tr|E7EVJ4|E7EVJ4_HUMAN,tr|E7EPX0|E7EPX0_HUMAN,tr|H0YBY0|H0YBY0_HUMAN,tr|E5RJ67|E5RJ67_HUMAN" 6 1334.7446 1.72 16249 16606 2 1334.747791 668.3796 Double-stranded RNA-binding protein Staufen homolog 2 OS=Homo sapiens OX=9606 GN=STAU2 PE=1 SV=2 8.56 3108.1 - 542741 - - - 2.4147 - 1.951 0.051 - 341.9 2 2 0 0.0032 13 0 0 0 1.54E+07 8.98E+06 - - - 0.9975 0.9998 221125_WJC_METTL3_EV_vs_WT_F02.16609.16609.2 0.000423 13/20 K.LSILYPATTGR[166.11].N sp|P30041|PRDX6_HUMAN 1 1200.6742 0.91 16250 16609 2 1200.672931 601.3444 Peroxiredoxin-6 OS=Homo sapiens OX=9606 GN=PRDX6 PE=1 SV=3 8.75 3108.4 - 3.91E+06 - - - -1.0511 - 2.44 0.36 - 574.2 1 2 0 -0.0013 11 0 0 0 7.69E+07 8.47E+07 - - - 4.1126 0.9962 221125_WJC_METTL3_EV_vs_WT_F02.16611.16611.2 0.00674 12-Aug K.WTWSAVR[166.11].G "sp|O75410|TACC1_HUMAN,tr|E5RJG6|E5RJG6_HUMAN" 2 914.4638 1.09 16252 16611 2 914.463019 458.2392 Transforming acidic coiled-coil-containing protein 1 OS=Homo sapiens OX=9606 GN=TACC1 PE=1 SV=2 9.75 3108.5 - 5.78E+06 - - - -0.8606 - 1.518 0.14 - 312.6 1 2 0 -0.0008 7 0 0 0 8.71E+07 7.99E+07 - - - 1.3973 0.9994 221125_WJC_METTL3_EV_vs_WT_F02.16612.16612.2 3.46E-05 13/22 R.IMNVIGEPIDER[166.11].G "sp|P06576|ATPB_HUMAN,tr|F8W079|F8W079_HUMAN,tr|H0YH81|H0YH81_HUMAN" 3 1394.7103 1.96 16253 16612 2 1394.706114 698.3624 "ATP synthase subunit beta, mitochondrial OS=Homo sapiens OX=9606 GN=ATP5F1B PE=1 SV=3" 4.14 3108.6 - 2.48E+06 - - - -3.0164 - 2.581 0.446 - 626.5 1 2 0 -0.0042 12 0 0 0 4.76E+08 2.42E+08 - - - 4.8286 0.9884 221125_WJC_METTL3_EV_vs_WT_F02.16614.16614.2 0.714 16-Jun R.AFNDPFIQK[136.11].E "sp|Q92598|HS105_HUMAN,tr|A0A0A0MSM0|A0A0A0MSM0_HUMAN,tr|R4GN69|R4GN69_HUMAN" 3 1086.5589 0.2 16255 16614 2 1086.557707 544.2867 Heat shock protein 105 kDa OS=Homo sapiens OX=9606 GN=HSPH1 PE=1 SV=1 5.88 3108.7 - 1.61E+06 - - - -1.1394 - 1.178 0.158 - 83.8 1 2 0 -0.0012 9 0 0 0 3.04E+07 1.50E+08 - - - 0.6815 0.9988 221125_WJC_METTL3_EV_vs_WT_F02.16621.16621.2 0.000557 20-Oct K.LVQLLGGVAEK[136.11].V sp|O00443|P3C2A_HUMAN 1 1133.69 0.64 16260 16621 2 1133.685931 567.8523 Phosphatidylinositol 4-phosphate 3-kinase C2 domain-containing subunit alpha OS=Homo sapiens OX=9606 GN=PIK3C2A PE=1 SV=2 6 3109.6 - 2.76E+06 - - - -3.5539 - 2.216 0.405 - 308.5 1 2 0 -0.004 11 0 0 0 2.83E+07 4.41E+07 - - - 4.1836 0.9995 221125_WJC_METTL3_EV_vs_WT_F02.16622.16622.2 0.087 20-Nov R.YALYDASFETK.E "sp|P60981|DEST_HUMAN,tr|F6RFD5|F6RFD5_HUMAN" 2 1306.6081 2 16261 16622 2 1306.605515 654.3113 Destrin OS=Homo sapiens OX=9606 GN=DSTN PE=1 SV=3 4.37 3109.7 - 1.07E+06 - - - -2.0044 - 2.018 0.389 - 319 1 2 0 -0.0026 11 0 0 0 1.55E+08 7.77E+07 - - - 3.8127 0.9986 221125_WJC_METTL3_EV_vs_WT_F02.16624.16624.2 0.00752 14-Sep R.LDYLSSLK.V "sp|P08195|4F2_HUMAN,tr|A0A7P0TAN7|A0A7P0TAN7_HUMAN,tr|J3KPF3|J3KPF3_HUMAN,tr|F5H0E2|F5H0E2_HUMAN,tr|F5H056|F5H056_HUMAN,tr|H0YH36|H0YH36_HUMAN,tr|A0A7P0TAT7|A0A7P0TAT7_HUMAN,tr|F5GZI0|F5GZI0_HUMAN,tr|H0YFS2|H0YFS2_HUMAN,tr|A0A7P0T8U7|A0A7P0T8U7_HUMAN,tr|A0A7P0T9F7|A0A7P0T9F7_HUMAN,tr|A0A7P0TBF8|A0A7P0TBF8_HUMAN,tr|A0A7P0T8F1|A0A7P0T8F1_HUMAN,tr|A0A7P0Z4A0|A0A7P0Z4A0_HUMAN,tr|F5GZS6|F5GZS6_HUMAN,tr|A0A7P0Z4P5|A0A7P0Z4P5_HUMAN,tr|A0A7P0TAS6|A0A7P0TAS6_HUMAN" 17 937.512 1.12 16263 16624 2 937.509166 469.7633 4F2 cell-surface antigen heavy chain OS=Homo sapiens OX=9606 GN=SLC3A2 PE=1 SV=3 5.83 3109.9 - 932636 - - - -3.0741 - 1.89 0.352 - 238.8 1 2 0 -0.0029 8 0 0 0 3.53E+07 3.14E+07 - - - 3.5599 0.9997 221125_WJC_METTL3_EV_vs_WT_F02.16625.16625.2 0.00528 20-Dec R.YALYDASFETK[136.11].E "sp|P60981|DEST_HUMAN,tr|F6RFD5|F6RFD5_HUMAN" 2 1314.6223 2 16264 16625 2 1314.622686 658.3184 Destrin OS=Homo sapiens OX=9606 GN=DSTN PE=1 SV=3 4.37 3110 - 739476 - - - 0.2678 - 2.248 0.328 - 442.1 1 2 0 0.0004 11 0 0 0 1.55E+08 7.77E+07 - - - 3.6548 0.9998 221125_WJC_METTL3_EV_vs_WT_F02.16632.16632.3 0.00436 Nov-52 R.ITPSYVAFTPEGER[166.11].L "sp|P11021|BIP_HUMAN,tr|A0A7P0TB36|A0A7P0TB36_HUMAN,tr|A0A7P0TAI0|A0A7P0TAI0_HUMAN" 3 1575.7808 0.24 16269 16632 3 1575.780132 526.2676 Endoplasmic reticulum chaperone BiP OS=Homo sapiens OX=9606 GN=HSPA5 PE=1 SV=2 4.53 3110.9 - 1.96E+06 - - - -0.4512 - 2.124 0.377 - 155.1 1 2 0 -0.0007 14 0 0 0 1.05E+07 4.38E+07 - - - 4.7449 0.9999 221125_WJC_METTL3_EV_vs_WT_F02.16634.16634.2 1.72E-07 26-Oct R.ITPSYVAFTPEGER[166.11].L "sp|P11021|BIP_HUMAN,tr|A0A7P0TB36|A0A7P0TB36_HUMAN,tr|A0A7P0TAI0|A0A7P0TAI0_HUMAN" 3 1575.7808 0.55 16271 16634 2 1575.780262 788.8977 Endoplasmic reticulum chaperone BiP OS=Homo sapiens OX=9606 GN=HSPA5 PE=1 SV=2 4.53 3111.1 - 5.19E+06 - - - -0.3687 - 2.198 0.612 - 292.5 1 2 0 -0.0006 14 0 0 0 8.54E+07 1.55E+08 - - - 5.5374 0.9991 221125_WJC_METTL3_EV_vs_WT_F02.16635.16635.2 0.0376 16-Sep K.FVSLLQEAK.D "sp|Q16254|E2F4_HUMAN,sp|Q15329|E2F5_HUMAN,tr|H3BTM3|H3BTM3_HUMAN,tr|H3BVE4|H3BVE4_HUMAN,tr|H3BMP3|H3BMP3_HUMAN" 5 1033.5808 2.25 16272 16635 2 1033.580717 517.7977 Transcription factor E2F4 OS=Homo sapiens OX=9606 GN=E2F4 PE=1 SV=2 6 3111.1 - 3.91E+06 - - - -0.0774 - 1.602 0.284 - 201.1 1 2 0 -0.0001 9 0 0 0 4.77E+07 2.12E+07 - - - 2.502 0.9999 221125_WJC_METTL3_EV_vs_WT_F02.16637.16637.2 3.11E-05 14/24 R.AVAVVVDPIQSVK[136.11].G sp|O00487|PSDE_HUMAN 1 1331.7904 0.88 16274 16637 2 1331.78859 666.9025 26S proteasome non-ATPase regulatory subunit 14 OS=Homo sapiens OX=9606 GN=PSMD14 PE=1 SV=1 5.88 3111.3 - 1.18E+06 - - - -1.3606 - 2.947 0.528 - 735.7 1 2 0 -0.0018 13 0 0 0 5.52E+07 6.29E+07 - - - 5.7141 0.9929 221125_WJC_METTL3_EV_vs_WT_F02.16638.16638.2 0.645 14-Aug K.QLFQLPAK[136.11].K "sp|Q15014|MO4L2_HUMAN,tr|Q5JXX2|Q5JXX2_HUMAN,tr|Q5JXX1|Q5JXX1_HUMAN" 3 951.5633 0.78 16275 16638 2 951.563695 476.7889 Mortality factor 4-like protein 2 OS=Homo sapiens OX=9606 GN=MORF4L2 PE=1 SV=1 8.75 3111.4 - 913614 - - - 0.413 - 1.368 0.123 - 232.7 1 2 0 0.0004 8 0 0 0 1.03E+07 1.32E+07 - - - 0.8944 0.8938 221125_WJC_METTL3_EV_vs_WT_F02.16641.16641.2 0.0558 14-Sep L.DNDIMLIK.L "sp|P35030|TRY3_HUMAN,tr|A0A7P0MNE9|A0A7P0MNE9_HUMAN" 2 960.495 5.38 16278 16641 2 960.492857 481.2548 Trypsin-3 OS=Homo sapiens OX=9606 GN=PRSS3 PE=1 SV=2 4.21 3111.8 - 615305 - - - -2.2499 - 1.749 0.255 - 312.4 1 1 0 -0.0022 8 0 0 0 1.21E+08 2.25E+07 - - - 2.6098 0.9975 221125_WJC_METTL3_EV_vs_WT_F02.16642.16642.2 0.255 14-Sep R.QLALWNPK.N "sp|Q9ULV4|COR1C_HUMAN,tr|B4E3S0|B4E3S0_HUMAN" 2 968.5444 1.1 16279 16642 2 968.544634 485.2795 Coronin-1C OS=Homo sapiens OX=9606 GN=CORO1C PE=1 SV=1 8.75 3111.9 - 408001 - - - 0.2922 - 1.65 0.149 - 241.6 1 2 0 0.0003 8 0 0 0 7.23E+06 6.58E+06 - - - 1.6517 0.9998 221125_WJC_METTL3_EV_vs_WT_F02.16647.16647.2 0.0206 20-Nov K.LLLIGDSGVGK[136.11].T "sp|P61006|RAB8A_HUMAN,sp|P51153|RAB13_HUMAN,sp|P61026|RAB10_HUMAN,sp|Q15286|RAB35_HUMAN,sp|Q9H0U4|RAB1B_HUMAN,sp|P59190|RAB15_HUMAN,sp|P62820|RAB1A_HUMAN,sp|Q92930|RAB8B_HUMAN,sp|Q92928|RAB1C_HUMAN,tr|H0YMN7|H0YMN7_HUMAN,tr|H0YL94|H0YL94_HUMAN,tr|A0A2R8YDI9|A0A2R8YDI9_HUMAN,tr|H0YNE9|H0YNE9_HUMAN,tr|G3V196|G3V196_HUMAN,tr|A0A2R8YFB8|A0A2R8YFB8_HUMAN,tr|H0YLJ8|H0YLJ8_HUMAN,tr|E9PLD0|E9PLD0_HUMAN,tr|E7END7|E7END7_HUMAN,tr|F5H157|F5H157_HUMAN" 19 1078.6478 1.04 16282 16647 2 1078.647706 540.3312 Ras-related protein Rab-8A OS=Homo sapiens OX=9606 GN=RAB8A PE=1 SV=1 5.84 3112.4 - 3.05E+06 - - - -0.0501 - 2.18 0.367 - 264.4 1 2 0 -0.0001 11 0 0 0 4.66E+07 4.48E+07 - - - 3.8599 0.9896 221125_WJC_METTL3_EV_vs_WT_F02.16649.16649.2 0.39 24-Aug R.IVSAQSLAEDDVE.- sp|Q15388|TOM20_HUMAN 1 1374.6515 - 16284 16649 2 1374.649932 688.333 Mitochondrial import receptor subunit TOM20 homolog OS=Homo sapiens OX=9606 GN=TOMM20 PE=1 SV=1 3.7 3112.6 - 1.86E+06 - - - -1.1079 - 1.314 0.136 - 152.8 1 2 0 -0.0015 13 0 0 0 - - - - - 0.7459 0.9955 221125_WJC_METTL3_EV_vs_WT_F02.16650.16650.2 0.112 12-Jun R.DFFQEVK.E "sp|O14530|TXND9_HUMAN,tr|F8WCJ3|F8WCJ3_HUMAN,tr|B8ZZX4|B8ZZX4_HUMAN" 3 911.4389 2.76 16285 16650 2 911.438122 456.7267 Thioredoxin domain-containing protein 9 OS=Homo sapiens OX=9606 GN=TXNDC9 PE=1 SV=2 4.37 3112.7 - 1.62E+06 - - - -0.8349 - 1.213 0.219 - 133.9 1 2 0 -0.0008 7 0 0 0 2.01E+07 7.29E+06 - - - 1.2701 0.9997 221125_WJC_METTL3_EV_vs_WT_F02.16651.16651.2 0.000641 16-Oct K.YMAC[160.03]C[160.03]LLYR[166.11].G "sp|Q71U36|TBA1A_HUMAN,sp|A6NHL2|TBAL3_HUMAN,sp|P68366|TBA4A_HUMAN,sp|P68363|TBA1B_HUMAN,sp|Q9BQE3|TBA1C_HUMAN,tr|A0A1W2PQM2|A0A1W2PQM2_HUMAN,tr|F5H5D3|F5H5D3_HUMAN" 7 1258.5536 0.37 16286 16651 2 1258.551137 630.2841 Tubulin alpha-1A chain OS=Homo sapiens OX=9606 GN=TUBA1A PE=1 SV=1 8.05 3112.8 - 1.34E+06 - - - -1.9777 - 1.642 0.566 - 372.2 1 2 0 -0.0025 9 0 0 0 6.56E+06 1.75E+07 - - - 4.6554 0.9962 221125_WJC_METTL3_EV_vs_WT_F02.16653.16653.2 0.221 16-Jul R.LLLPTPTVK.Q "sp|Q8IX12|CCAR1_HUMAN,tr|A0A0C4DGG8|A0A0C4DGG8_HUMAN" 2 980.627 6.21 16288 16653 2 980.626264 491.3208 Cell division cycle and apoptosis regulator protein 1 OS=Homo sapiens OX=9606 GN=CCAR1 PE=1 SV=2 8.75 3113 - 1.12E+06 - - - -0.7689 - 1.283 0.217 - 117.3 1 2 0 -0.0008 9 0 0 0 2.27E+07 3.66E+06 - - - 1.3645 0.9857 221125_WJC_METTL3_EV_vs_WT_F02.16655.16655.2 1.01 12-Jul R.DLGAYLR.Q "sp|Q9BRT2|UQCC2_HUMAN,tr|Q5TAQ0|Q5TAQ0_HUMAN,tr|V5IRT4|V5IRT4_HUMAN" 3 806.4287 1.3 16290 16655 2 806.429091 404.2216 Ubiquinol-cytochrome-c reductase complex assembly factor 2 OS=Homo sapiens OX=9606 GN=UQCC2 PE=1 SV=1 5.84 3113.3 - 926341 - - - 0.5431 - 1.376 0.053 - 173.7 1 2 0 0.0004 7 0 0 0 1.10E+07 8.52E+06 - - - 0.4437 0.9992 221125_WJC_METTL3_EV_vs_WT_F02.16656.16656.3 0.00783 Oct-44 R.IMNVIGEPIDER.G "sp|P06576|ATPB_HUMAN,tr|F8W079|F8W079_HUMAN,tr|H0YH81|H0YH81_HUMAN" 3 1384.7021 2.16 16291 16656 3 1384.701056 462.5746 "ATP synthase subunit beta, mitochondrial OS=Homo sapiens OX=9606 GN=ATP5F1B PE=1 SV=3" 4.14 3113.4 - 800490 - - - -0.7186 - 2.197 0.249 - 197 1 2 0 -0.001 12 0 0 0 1.25E+07 5.76E+06 - - - 3.4975 0.9777 221125_WJC_METTL3_EV_vs_WT_F02.16657.16657.2 0.163 12-Jun R.SYVDLLK[136.11].L "sp|Q9BXJ9|NAA15_HUMAN,tr|A0A0B4J1W3|A0A0B4J1W3_HUMAN" 2 844.4786 0.76 16292 16657 2 844.477003 423.2466 "N-alpha-acetyltransferase 15, NatA auxiliary subunit OS=Homo sapiens OX=9606 GN=NAA15 PE=1 SV=1" 5.55 3113.5 - 457700 - - - -1.8556 - 1.025 0.19 - 127.1 1 2 0 -0.0016 7 0 0 0 6.37E+06 8.38E+06 - - - 0.5221 0.9983 221125_WJC_METTL3_EV_vs_WT_F02.16659.16659.2 0.0225 24-Sep R.MLEGGEDPLYVAR[166.11].R sp|Q96S55|WRIP1_HUMAN 1 1458.7052 0.15 16294 16659 2 1458.703662 730.3599 ATPase WRNIP1 OS=Homo sapiens OX=9606 GN=WRNIP1 PE=1 SV=2 4.14 3113.8 - 293406 - - - -1.0784 - 1.554 0.264 - 65.8 1 2 0 -0.0016 13 0 0 0 9.61E+05 6.60E+06 - - - 2.1218 0.9995 221125_WJC_METTL3_EV_vs_WT_F02.16664.16664.2 0.00145 20-Aug K.TLGDFAAEYAK[136.11].S "sp|P09874|PARP1_HUMAN,tr|A0A7I2V5E9|A0A7I2V5E9_HUMAN,tr|A0A7I2V625|A0A7I2V625_HUMAN,tr|A0A7I2V3E1|A0A7I2V3E1_HUMAN" 4 1192.5856 1.21 16298 16664 2 1192.58625 597.3001 Poly [ADP-ribose] polymerase 1 OS=Homo sapiens OX=9606 GN=PARP1 PE=1 SV=4 4.37 3114.1 - 4.57E+06 - - - 0.5836 - 1.422 0.437 - 110.5 1 2 0 0.0007 11 0 0 0 5.16E+08 4.28E+08 - - - 3.2209 0.9976 221125_WJC_METTL3_EV_vs_WT_F02.16665.16665.2 8.75 14-Aug R.LDYLSSLK[136.11].V "sp|P08195|4F2_HUMAN,tr|A0A7P0TAN7|A0A7P0TAN7_HUMAN,tr|J3KPF3|J3KPF3_HUMAN,tr|F5H0E2|F5H0E2_HUMAN,tr|F5H056|F5H056_HUMAN,tr|H0YH36|H0YH36_HUMAN,tr|A0A7P0TAT7|A0A7P0TAT7_HUMAN,tr|F5GZI0|F5GZI0_HUMAN,tr|H0YFS2|H0YFS2_HUMAN,tr|A0A7P0T8U7|A0A7P0T8U7_HUMAN,tr|A0A7P0T9F7|A0A7P0T9F7_HUMAN,tr|A0A7P0TBF8|A0A7P0TBF8_HUMAN,tr|A0A7P0T8F1|A0A7P0T8F1_HUMAN,tr|A0A7P0Z4A0|A0A7P0Z4A0_HUMAN,tr|F5GZS6|F5GZS6_HUMAN,tr|A0A7P0Z4P5|A0A7P0Z4P5_HUMAN,tr|A0A7P0TAS6|A0A7P0TAS6_HUMAN" 17 945.5262 1.13 16299 16665 2 945.526288 473.7704 4F2 cell-surface antigen heavy chain OS=Homo sapiens OX=9606 GN=SLC3A2 PE=1 SV=3 5.83 3114.2 - 3.27E+06 - - - 0.0423 - 1.655 0.147 - 176.5 1 2 0 0 8 0 0 0 3.55E+07 3.14E+07 - - - 1.6462 0.9883 221125_WJC_METTL3_EV_vs_WT_F02.16666.16666.2 1.16 12-Aug R.NLLQELK[136.11].V "sp|Q9NTJ3|SMC4_HUMAN,tr|E9PD53|E9PD53_HUMAN" 2 864.516 0.63 16300 16666 2 864.516004 433.2653 Structural maintenance of chromosomes protein 4 OS=Homo sapiens OX=9606 GN=SMC4 PE=1 SV=2 6 3114.3 - 1.11E+06 - - - -0.0162 - 1.364 0.066 - 197.2 1 2 0 0 7 0 0 0 1.56E+07 2.47E+07 - - - 0.5121 0.9998 221125_WJC_METTL3_EV_vs_WT_F02.16667.16667.2 0.000319 22-Nov K.ELGLDEGVDSLK.A sp|Q8WXX5|DNJC9_HUMAN 1 1273.6402 1.36 16301 16667 2 1273.640284 637.8274 DnaJ homolog subfamily C member 9 OS=Homo sapiens OX=9606 GN=DNAJC9 PE=1 SV=1 3.92 3114.4 - 1.11E+06 - - - 0.0958 - 2.057 0.479 - 372.8 1 2 0 0.0001 12 0 0 0 4.34E+07 3.20E+07 - - - 4.4766 0.999 221125_WJC_METTL3_EV_vs_WT_F02.16668.16668.2 0.0106 16-Sep R.NLQDPFYPR.G "sp|Q96EI5|TCAL4_HUMAN,sp|Q9H3H9|TCAL2_HUMAN,tr|A2RQR6|A2RQR6_HUMAN" 3 1148.5615 3.34 16302 16668 2 1148.560755 575.288 Transcription elongation factor A protein-like 4 OS=Homo sapiens OX=9606 GN=TCEAL4 PE=1 SV=2 5.84 3114.5 - 1.07E+06 - - - -0.6121 - 1.433 0.315 - 302.8 1 2 0 -0.0007 9 0 0 0 1.19E+07 3.56E+06 - - - 2.4082 0.9951 221125_WJC_METTL3_EV_vs_WT_F02.16669.16669.2 0.0155 14-Sep R.QLALWNPK[136.11].N "sp|Q9ULV4|COR1C_HUMAN,tr|B4E3S0|B4E3S0_HUMAN" 2 976.5586 1.01 16303 16669 2 976.562238 489.2866 Coronin-1C OS=Homo sapiens OX=9606 GN=CORO1C PE=1 SV=1 8.75 3114.6 - 930463 - - - 3.7755 - 1.645 0.31 - 284.5 1 2 0 0.0037 8 0 0 0 1.37E+07 1.36E+07 - - - 2.8307 0.9998 221125_WJC_METTL3_EV_vs_WT_F02.16671.16671.2 0.00342 24-Nov R.LIEQEEYLNVQVK[136.11].E "sp|Q9NTJ3|SMC4_HUMAN,tr|E9PD53|E9PD53_HUMAN" 2 1611.8599 0.59 16305 16671 2 1611.858746 806.9372 Structural maintenance of chromosomes protein 4 OS=Homo sapiens OX=9606 GN=SMC4 PE=1 SV=2 4.25 3114.9 - 387958 - - - -0.7395 - 2.212 0.467 - 279.1 1 2 0 -0.0012 13 0 0 0 2.21E+06 3.71E+06 - - - 4.5274 0.9993 221125_WJC_METTL3_EV_vs_WT_F02.16676.16676.2 0.00408 22-Oct K.VIVDFSSPNIAK.E sp|P54136|SYRC_HUMAN 1 1288.7027 1.03 16308 16676 2 1288.70553 645.3586 "Arginine--tRNA ligase, cytoplasmic OS=Homo sapiens OX=9606 GN=RARS1 PE=1 SV=2" 5.81 3115.5 - 6.15E+06 - - - 2.1937 - 1.832 0.422 - 222.6 1 2 0 0.0028 12 0 0 0 8.58E+07 8.30E+07 - - - 3.7499 0.9998 221125_WJC_METTL3_EV_vs_WT_F02.16681.16681.2 2.87E-05 14-Aug K.DVEDMFSR.F "sp|Q15717|ELAV1_HUMAN,tr|M0R055|M0R055_HUMAN,tr|M0QZR9|M0QZR9_HUMAN" 3 997.4175 1.28 16313 16681 2 997.417602 499.716 ELAV-like protein 1 OS=Homo sapiens OX=9606 GN=ELAVL1 PE=1 SV=2 4.03 3116 - 967589 - - - 0.1063 - 1.541 0.546 - 218.3 1 2 0 0.0001 8 0 0 0 1.51E+08 1.18E+08 - - - 4.3779 0.9999 221125_WJC_METTL3_EV_vs_WT_F02.16683.16683.3 0.00525 13/40 R.AVAQALEVIPR[166.11].T "sp|P49368|TCPG_HUMAN,tr|B4DUR8|B4DUR8_HUMAN" 2 1175.6902 0.22 16315 16683 3 1175.68809 392.904 T-complex protein 1 subunit gamma OS=Homo sapiens OX=9606 GN=CCT3 PE=1 SV=4 6.05 3116.2 - 758805 - - - -1.776 - 2.564 0.377 - 267.3 1 2 0 -0.0021 11 0 0 0 2.04E+07 9.39E+07 - - - 5.4174 0.9999 221125_WJC_METTL3_EV_vs_WT_F02.16684.16684.3 0.000119 Oct-44 R.IMNVIGEPIDER[166.11].G "sp|P06576|ATPB_HUMAN,tr|F8W079|F8W079_HUMAN,tr|H0YH81|H0YH81_HUMAN" 3 1394.7103 2.16 16316 16684 3 1394.710751 465.9107 "ATP synthase subunit beta, mitochondrial OS=Homo sapiens OX=9606 GN=ATP5F1B PE=1 SV=3" 4.14 3116.4 - 637947 - - - 0.3083 - 2.304 0.389 - 188.6 1 2 0 0.0004 12 0 0 0 1.25E+07 5.76E+06 - - - 5.1904 0.9989 221125_WJC_METTL3_EV_vs_WT_F02.16685.16685.2 0.00196 16-Oct K.TDELLALGR.E sp|P12270|TPR_HUMAN 1 986.5397 2.61 16317 16685 2 986.54285 494.2771 Nucleoprotein TPR OS=Homo sapiens OX=9606 GN=TPR PE=1 SV=3 4.37 3116.5 - 477399 - - - 3.2335 - 2.104 0.393 - 504.3 1 2 0 0.0032 9 0 0 0 1.02E+08 3.92E+07 - - - 4.0947 0.9996 221125_WJC_METTL3_EV_vs_WT_F02.16689.16689.2 0.025 18-Oct R.ALEEELAGLK[136.11].N sp|O95347|SMC2_HUMAN 1 1079.5954 1.16 16320 16689 2 1079.594632 540.805 Structural maintenance of chromosomes protein 2 OS=Homo sapiens OX=9606 GN=SMC2 PE=1 SV=2 4.25 3117 - 2.16E+06 - - - -0.703 - 1.953 0.319 - 283.6 1 2 0 -0.0008 10 0 0 0 3.93E+07 3.39E+07 - - - 3.2653 0.9997 221125_WJC_METTL3_EV_vs_WT_F02.16691.16691.2 0.00463 16-Oct R.SPSWYGIPR.L "sp|P78347|GTF2I_HUMAN,tr|A0A494C0Q7|A0A494C0Q7_HUMAN,tr|A0A494C1K3|A0A494C1K3_HUMAN" 3 1061.5294 1.52 16321 16691 2 1061.52916 531.772 General transcription factor II-I OS=Homo sapiens OX=9606 GN=GTF2I PE=1 SV=2 8.46 3117.2 - 6.20E+06 - - - -0.2543 - 1.879 0.344 - 468.4 1 2 0 -0.0003 9 0 0 0 5.98E+08 3.94E+08 - - - 3.4065 0.9991 221125_WJC_METTL3_EV_vs_WT_F02.16692.16692.2 0.0149 16-Aug K.EVYDIAFSR.A "sp|P61962|DCAF7_HUMAN,tr|A0A087WWI6|A0A087WWI6_HUMAN" 2 1098.5346 1.04 16322 16692 2 1098.533845 550.2746 DDB1- and CUL4-associated factor 7 OS=Homo sapiens OX=9606 GN=DCAF7 PE=1 SV=1 4.37 3117.2 - 4.28E+06 - - - -0.6645 - 1.54 0.309 - 270.4 1 2 0 -0.0007 9 0 0 0 5.30E+07 5.11E+07 - - - 2.5722 0.9973 221125_WJC_METTL3_EV_vs_WT_F02.16693.16693.2 0.0613 18-Jul K.ATIGADFLTK.E "sp|P51149|RAB7A_HUMAN,tr|C9J592|C9J592_HUMAN,tr|C9J4V0|C9J4V0_HUMAN,tr|C9J7D1|C9J7D1_HUMAN,tr|A0A6Q8PH84|A0A6Q8PH84_HUMAN,tr|C9J8S3|C9J8S3_HUMAN,tr|C9IZZ0|C9IZZ0_HUMAN,tr|C9J4S4|C9J4S4_HUMAN,tr|A0A6Q8PGE6|A0A6Q8PGE6_HUMAN,tr|A0A6Q8PF79|A0A6Q8PF79_HUMAN,tr|A0A6Q8PG52|A0A6Q8PG52_HUMAN" 11 1035.5601 0.39 16323 16693 2 1035.559906 518.7873 Ras-related protein Rab-7a OS=Homo sapiens OX=9606 GN=RAB7A PE=1 SV=1 5.88 3117.3 - 2.55E+06 - - - -0.1497 - 1.471 0.193 - 118 1 2 0 -0.0002 10 0 0 0 2.19E+08 5.59E+08 - - - 1.5437 0.9963 221125_WJC_METTL3_EV_vs_WT_F02.16694.16694.2 0.13 20-Aug R.YEILTPNSIPK[136.11].G sp|P35579|MYH9_HUMAN 1 1281.706 0.95 16324 16694 2 1281.706162 641.8603 Myosin-9 OS=Homo sapiens OX=9606 GN=MYH9 PE=1 SV=4 6 3117.4 - 2.09E+06 - - - 0.1233 - 1.478 0.167 - 219.4 1 2 0 0.0002 11 0 0 0 6.37E+07 6.74E+07 - - - 1.3313 0.9971 221125_WJC_METTL3_EV_vs_WT_F02.16695.16695.2 1.17 20-Aug R.YEILTPNSIPK.G sp|P35579|MYH9_HUMAN 1 1273.6918 0.41 16325 16695 2 1273.692668 637.8532 Myosin-9 OS=Homo sapiens OX=9606 GN=MYH9 PE=1 SV=4 6 3117.4 - 1.96E+06 - - - 0.6783 - 1.446 0.214 - 218.4 1 2 0 0.0009 11 0 0 0 6.95E+07 1.68E+08 - - - 1.619 1 221125_WJC_METTL3_EV_vs_WT_F02.16697.16697.2 1.01E-05 15/22 K.LVILANNC[160.03]PALR[166.11].K "sp|P62888|RL30_HUMAN,tr|E5RJH3|E5RJH3_HUMAN,tr|E5RI99|E5RI99_HUMAN" 3 1362.7681 1.04 16327 16697 2 1362.768082 682.3913 60S ribosomal protein L30 OS=Homo sapiens OX=9606 GN=RPL30 PE=1 SV=2 8.25 3117.6 - 1.67E+06 - - - -0.0213 - 2.863 0.555 - 872.3 1 2 0 0 12 0 0 0 3.46E+08 3.33E+08 - - - 5.9079 0.9996 221125_WJC_METTL3_EV_vs_WT_F02.16698.16698.2 0.00137 16-Oct R.INMVEELEK.A sp|Q15046|SYK_HUMAN 1 1103.5533 0.73 16328 16698 2 1103.552085 552.7839 Lysine--tRNA ligase OS=Homo sapiens OX=9606 GN=KARS1 PE=1 SV=3 4.25 3117.6 - 1.35E+06 - - - -1.0656 - 2.145 0.314 - 284.5 1 2 0 -0.0012 9 0 0 0 3.35E+07 4.61E+07 - - - 3.5676 0.9998 221125_WJC_METTL3_EV_vs_WT_F02.16699.16699.2 0.045 22-Dec K.LVILANNC[160.03]PALR.K "sp|P62888|RL30_HUMAN,tr|E5RJH3|E5RJH3_HUMAN,tr|E5RI99|E5RI99_HUMAN" 3 1352.7598 1.05 16329 16699 2 1352.760166 677.3872 60S ribosomal protein L30 OS=Homo sapiens OX=9606 GN=RPL30 PE=1 SV=2 8.25 3117.7 - 1.02E+06 - - - 0.2402 - 2.457 0.354 - 585.4 1 2 0 0.0003 12 0 0 0 3.50E+08 3.34E+08 - - - 4.0208 0.9998 221125_WJC_METTL3_EV_vs_WT_F02.16702.16702.2 0.00395 13/20 R.AVAQALEVIPR[166.11].T "sp|P49368|TCPG_HUMAN,tr|B4DUR8|B4DUR8_HUMAN" 2 1175.6902 0.21 16330 16702 2 1175.690429 588.8524 T-complex protein 1 subunit gamma OS=Homo sapiens OX=9606 GN=CCT3 PE=1 SV=4 6.05 3118.1 - 2.00E+07 - - - 0.2135 - 2.636 0.387 - 851.6 1 2 0 0.0003 11 0 0 0 3.31E+08 1.62E+09 - - - 4.5214 0.9997 221125_WJC_METTL3_EV_vs_WT_F02.16703.16703.2 0.00331 14-Oct R.QLAEDFLR.D "sp|Q92841|DDX17_HUMAN,tr|A0A5H1ZRQ2|A0A5H1ZRQ2_HUMAN,tr|A0A1X7SBZ2|A0A1X7SBZ2_HUMAN" 3 990.5134 1.11 16331 16703 2 990.512841 496.264 Probable ATP-dependent RNA helicase DDX17 OS=Homo sapiens OX=9606 GN=DDX17 PE=1 SV=2 4.37 3118.2 - 2.41E+06 - - - -0.6098 - 1.835 0.358 - 577 1 2 0 -0.0006 8 0 0 0 2.14E+08 1.92E+08 - - - 3.5158 0.9996 221125_WJC_METTL3_EV_vs_WT_F02.16704.16704.2 0.48 16-Nov K.TNSILFYGR.F "sp|P48594|SPB4_HUMAN,sp|P29508|SPB3_HUMAN,tr|H0Y5H9|H0Y5H9_HUMAN" 3 1069.5556 35.45 16332 16704 2 1069.553506 535.7851 Serpin B4 OS=Homo sapiens OX=9606 GN=SERPINB4 PE=1 SV=2 8.41 3118.2 - 4.84E+06 - - - -1.999 - 2.224 0.376 - 676.2 1 2 0 -0.0021 9 0 0 0 1.14E+08 3.22E+06 - - - 4.1299 0.8417 221125_WJC_METTL3_EV_vs_WT_F02.16707.16707.2 0.277 18-Sep K.EQIDPALFAK.P sp|Q6IQ49|SDE2_HUMAN 1 1130.5972 1.31 16335 16707 2 1130.597446 566.3059 Replication stress response regulator SDE2 OS=Homo sapiens OX=9606 GN=SDE2 PE=1 SV=1 4.37 3118.4 - 1.07E+06 - - - 0.2397 - 1.647 0.14 - 183.6 1 1 0 0.0003 10 0 0 0 1.37E+08 1.04E+08 - - - 1.4677 1 221125_WJC_METTL3_EV_vs_WT_F02.16711.16711.3 0.000272 Dec-40 R.AVAQALEVIPR.T "sp|P49368|TCPG_HUMAN,tr|B4DUR8|B4DUR8_HUMAN" 2 1165.6819 0.22 16339 16711 3 1165.681225 389.5679 T-complex protein 1 subunit gamma OS=Homo sapiens OX=9606 GN=CCT3 PE=1 SV=4 6.05 3118.9 - 388281 - - - -0.5859 - 2.674 0.468 - 193.3 1 2 0 -0.0007 11 0 0 0 2.04E+07 9.39E+07 - - - 6.5517 1 221125_WJC_METTL3_EV_vs_WT_F02.16712.16712.2 9.58E-09 17/28 R.NFILDQTNVSAAAQR.R "sp|Q00839|HNRPU_HUMAN,tr|A0A1W2PQL0|A0A1W2PQL0_HUMAN,tr|A0A1W2PPL4|A0A1W2PPL4_HUMAN,tr|A0A1W2PQ74|A0A1W2PQ74_HUMAN,tr|Q5RI18|Q5RI18_HUMAN,tr|A0A1W2PP35|A0A1W2PP35_HUMAN,tr|A0A1W2PPS1|A0A1W2PPS1_HUMAN,tr|A0A1W2PRZ7|A0A1W2PRZ7_HUMAN,tr|A0A1W2PPH7|A0A1W2PPH7_HUMAN,tr|A0A1W2PQD4|A0A1W2PQD4_HUMAN,tr|A0A1W2PP34|A0A1W2PP34_HUMAN,tr|A0A1X7SBS1|A0A1X7SBS1_HUMAN" 12 1646.8376 0.92 16340 16712 2 1646.838632 824.4261 Heterogeneous nuclear ribonucleoprotein U OS=Homo sapiens OX=9606 GN=HNRNPU PE=1 SV=6 5.84 3119.1 - 316943 - - - 0.6066 - 3.153 0.569 - 1052.1 1 2 0 0.001 15 0 0 0 1.02E+07 1.11E+07 - - - 6.0666 0.9998 221125_WJC_METTL3_EV_vs_WT_F02.16715.16715.2 0.000804 13/20 R.AVAQALEVIPR.T "sp|P49368|TCPG_HUMAN,tr|B4DUR8|B4DUR8_HUMAN" 2 1165.6819 0.21 16341 16715 2 1165.681929 583.8482 T-complex protein 1 subunit gamma OS=Homo sapiens OX=9606 GN=CCT3 PE=1 SV=4 6.05 3119.5 - 6.65E+06 - - - 0.018 - 2.587 0.381 - 891.6 1 2 0 0 11 0 0 0 3.31E+08 1.62E+09 - - - 4.4264 0.9998 221125_WJC_METTL3_EV_vs_WT_F02.16717.16717.2 0.0039 18-Nov R.FDAGELITQR.E "sp|P35232|PHB_HUMAN,tr|C9JZ20|C9JZ20_HUMAN,tr|E7ESE2|E7ESE2_HUMAN,tr|E9PCW0|E9PCW0_HUMAN,tr|C9JW96|C9JW96_HUMAN" 5 1148.5826 1.39 16343 16717 2 1148.584621 575.2986 Prohibitin OS=Homo sapiens OX=9606 GN=PHB PE=1 SV=1 4.37 3119.6 - 3.81E+06 - - - 1.77 - 2.337 0.472 - 471.2 1 2 0 0.002 10 0 0 0 1.08E+08 7.76E+07 - - - 4.896 0.9997 221125_WJC_METTL3_EV_vs_WT_F02.16718.16718.2 0.000273 16-Nov R.INMVEELEK[136.11].A sp|Q15046|SYK_HUMAN 1 1111.5675 0.73 16344 16718 2 1111.567682 556.791 Lysine--tRNA ligase OS=Homo sapiens OX=9606 GN=KARS1 PE=1 SV=3 4.25 3119.6 - 3.11E+06 - - - 0.1988 - 2.263 0.31 - 343 1 2 0 0.0002 9 0 0 0 3.35E+07 4.62E+07 - - - 3.6933 0.9998 221125_WJC_METTL3_EV_vs_WT_F02.16719.16719.2 1.54E-06 22-Dec R.LNVGGTYFVTTR.Q sp|Q14681|KCTD2_HUMAN 1 1326.6932 4.24 16345 16719 2 1326.69227 664.3539 BTB\POZ domain-containing protein KCTD2 OS=Homo sapiens OX=9606 GN=KCTD2 PE=1 SV=3 8.75 3119.7 - 3.10E+06 - - - -0.7017 - 2.567 0.386 - 479.1 1 2 0 -0.0009 12 0 0 0 5.01E+08 1.18E+08 - - - 4.3722 0.9996 221125_WJC_METTL3_EV_vs_WT_F02.16720.16720.2 0.00822 16-Aug K.ELPQVSFVK[136.11].L sp|O76003|GLRX3_HUMAN 1 1053.595 3.52 16346 16720 2 1053.594352 527.8048 Glutaredoxin-3 OS=Homo sapiens OX=9606 GN=GLRX3 PE=1 SV=2 6.1 3119.7 - 2.77E+06 - - - -0.6122 - 1.456 0.419 - 252.9 1 2 0 -0.0006 9 0 0 0 1.82E+08 5.17E+07 - - - 3.2224 0.9986 221125_WJC_METTL3_EV_vs_WT_F02.16721.16721.2 0.0682 14-Aug R.SSLAEYFK.D "sp|Q9UBU9|NXF1_HUMAN,tr|E9PIN3|E9PIN3_HUMAN" 2 943.4651 0.88 16347 16721 2 943.463141 472.7398 Nuclear RNA export factor 1 OS=Homo sapiens OX=9606 GN=NXF1 PE=1 SV=1 5.72 3119.8 - 2.70E+06 - - - -2.0743 - 1.586 0.319 - 208.3 1 2 0 -0.002 8 0 0 0 5.13E+07 5.87E+07 - - - 2.7875 0.9794 221125_WJC_METTL3_EV_vs_WT_F02.16722.16722.2 0.757 12-Jul K.TYLFLQK.Y "sp|Q9UIV8|SPB13_HUMAN,tr|F8WE70|F8WE70_HUMAN,tr|C9JL93|C9JL93_HUMAN,tr|A0A0A0MQW3|A0A0A0MQW3_HUMAN" 4 911.5117 12.99 16348 16722 2 911.510291 456.7631 Serpin B13 OS=Homo sapiens OX=9606 GN=SERPINB13 PE=1 SV=2 8.26 3119.9 - 770252 - - - -1.4953 - 1.263 0.105 - 162.1 2 2 0 -0.0014 7 0 0 0 8.68E+06 6.68E+05 - - - 0.4215 0.9976 221125_WJC_METTL3_EV_vs_WT_F02.16726.16726.2 0.000366 18-Aug R.FDAGELITQR[166.11].E "sp|P35232|PHB_HUMAN,tr|C9JZ20|C9JZ20_HUMAN,tr|E7ESE2|E7ESE2_HUMAN,tr|E9PCW0|E9PCW0_HUMAN,tr|C9JW96|C9JW96_HUMAN" 5 1158.5909 1.39 16350 16726 2 1158.58733 580.3027 Prohibitin OS=Homo sapiens OX=9606 GN=PHB PE=1 SV=1 4.37 3120.4 - 3.44E+06 - - - -3.0451 - 1.899 0.293 - 227.8 1 2 0 -0.0035 10 0 0 0 1.08E+08 7.76E+07 - - - 2.9941 0.9998 221125_WJC_METTL3_EV_vs_WT_F02.16727.16727.2 5.67E-05 16-Sep K.TQTILFYGR.V sp|Q96P63|SPB12_HUMAN 1 1097.5869 1068.82 16351 16727 2 1097.587519 549.8007 Serpin B12 OS=Homo sapiens OX=9606 GN=SERPINB12 PE=1 SV=1 8.41 3120.5 - 2.14E+06 - - - 0.523 - 1.954 0.443 - 398.3 1 2 0 0.0006 9 0 0 0 1.09E+08 1.02E+05 - - - 4.2508 0.9993 221125_WJC_METTL3_EV_vs_WT_F02.16728.16728.2 0.00367 14-Sep R.QLAEDFLR[166.11].D "sp|Q92841|DDX17_HUMAN,tr|A0A5H1ZRQ2|A0A5H1ZRQ2_HUMAN,tr|A0A1X7SBZ2|A0A1X7SBZ2_HUMAN" 3 1000.5217 1.11 16352 16728 2 1000.5212 501.2681 Probable ATP-dependent RNA helicase DDX17 OS=Homo sapiens OX=9606 GN=DDX17 PE=1 SV=2 4.37 3120.5 - 9.35E+06 - - - -0.5147 - 1.975 0.229 - 487.4 1 2 0 -0.0005 8 0 0 0 2.13E+08 1.92E+08 - - - 2.7848 0.9771 221125_WJC_METTL3_EV_vs_WT_F02.16729.16729.2 0.0135 16-Jul R.AFNDPFIQK.E "sp|Q92598|HS105_HUMAN,tr|A0A0A0MSM0|A0A0A0MSM0_HUMAN,tr|R4GN69|R4GN69_HUMAN" 3 1078.5447 0.18 16353 16729 2 1078.542093 540.2796 Heat shock protein 105 kDa OS=Homo sapiens OX=9606 GN=HSPH1 PE=1 SV=1 5.88 3120.6 - 1.11E+06 - - - -2.4589 - 1.309 0.132 - 110.3 1 2 0 -0.0027 9 0 0 0 2.53E+07 1.43E+08 - - - 0.7941 0.9999 221125_WJC_METTL3_EV_vs_WT_F02.16730.16730.2 7.76E-07 13/28 R.NFILDQTNVSAAAQR[166.11].R "sp|Q00839|HNRPU_HUMAN,tr|A0A1W2PQL0|A0A1W2PQL0_HUMAN,tr|A0A1W2PPL4|A0A1W2PPL4_HUMAN,tr|A0A1W2PQ74|A0A1W2PQ74_HUMAN,tr|Q5RI18|Q5RI18_HUMAN,tr|A0A1W2PP35|A0A1W2PP35_HUMAN,tr|A0A1W2PPS1|A0A1W2PPS1_HUMAN,tr|A0A1W2PRZ7|A0A1W2PRZ7_HUMAN,tr|A0A1W2PPH7|A0A1W2PPH7_HUMAN,tr|A0A1W2PQD4|A0A1W2PQD4_HUMAN,tr|A0A1W2PP34|A0A1W2PP34_HUMAN,tr|A0A1X7SBS1|A0A1X7SBS1_HUMAN" 12 1656.8459 0.92 16354 16730 2 1656.843724 829.4302 Heterogeneous nuclear ribonucleoprotein U OS=Homo sapiens OX=9606 GN=HNRNPU PE=1 SV=6 5.84 3120.7 - 901605 - - - -1.3151 - 2.675 0.522 - 537.1 1 2 0 -0.0022 15 0 0 0 1.02E+07 1.11E+07 - - - 5.3149 0.9997 221125_WJC_METTL3_EV_vs_WT_F02.16731.16731.3 0.000157 Dec-44 K.LVILANNC[160.03]PALR.K "sp|P62888|RL30_HUMAN,tr|E5RJH3|E5RJH3_HUMAN,tr|E5RI99|E5RI99_HUMAN" 3 1352.7598 0.94 16355 16731 3 1352.763349 451.9272 60S ribosomal protein L30 OS=Homo sapiens OX=9606 GN=RPL30 PE=1 SV=2 8.25 3120.8 - 621769 - - - 2.5932 - 2.141 0.403 - 189.1 1 2 0 0.0035 12 0 0 0 1.96E+07 2.09E+07 - - - 5.1422 0.9999 221125_WJC_METTL3_EV_vs_WT_F02.16734.16734.2 8.89E-06 24-Aug R.GFETAYC[160.03]IDSMGK[136.11].T "sp|Q86SF2|GALT7_HUMAN,tr|H0YAK0|H0YAK0_HUMAN,tr|H0YAH3|H0YAH3_HUMAN" 3 1485.636 2.24 16358 16734 2 1485.635124 743.8253 N-acetylgalactosaminyltransferase 7 OS=Homo sapiens OX=9606 GN=GALNT7 PE=1 SV=1 4.37 3121.2 - 171264 - - - -0.5573 - 1.686 0.567 - 120.8 1 2 0 -0.0008 13 0 0 0 4.20E+06 1.87E+06 - - - 4.5693 0.9998 221125_WJC_METTL3_EV_vs_WT_F02.16736.16736.2 1.14E-07 20-Oct K.TLGDFAAEYAK.S "sp|P09874|PARP1_HUMAN,tr|A0A7I2V5E9|A0A7I2V5E9_HUMAN,tr|A0A7I2V625|A0A7I2V625_HUMAN,tr|A0A7I2V3E1|A0A7I2V3E1_HUMAN" 4 1184.5714 1.23 16359 16736 2 1184.570937 593.293 Poly [ADP-ribose] polymerase 1 OS=Homo sapiens OX=9606 GN=PARP1 PE=1 SV=4 4.37 3121.4 - 3.20E+07 - - - -0.352 - 2.006 0.448 - 180.4 1 2 0 -0.0004 11 0 0 0 5.26E+08 4.28E+08 - - - 4.233 0.9999 221125_WJC_METTL3_EV_vs_WT_F02.16739.16739.3 1.33E-05 15/44 K.LVILANNC[160.03]PALR[166.11].K "sp|P62888|RL30_HUMAN,tr|E5RJH3|E5RJH3_HUMAN,tr|E5RI99|E5RI99_HUMAN" 3 1362.7681 0.94 16362 16739 3 1362.768377 455.2633 60S ribosomal protein L30 OS=Homo sapiens OX=9606 GN=RPL30 PE=1 SV=2 8.25 3121.6 - 1.07E+06 - - - 0.1952 - 2.362 0.444 - 377.3 1 2 0 0.0003 12 0 0 0 1.96E+07 2.09E+07 - - - 5.8725 0.9998 221125_WJC_METTL3_EV_vs_WT_F02.16748.16748.2 0.00588 18-Jul R.LVQAFQFTDK.H "sp|Q06830|PRDX1_HUMAN,tr|A0A0A0MRQ5|A0A0A0MRQ5_HUMAN,tr|A0A0A0MSI0|A0A0A0MSI0_HUMAN" 3 1195.6237 0.66 16369 16748 2 1195.624151 598.8191 Peroxiredoxin-1 OS=Homo sapiens OX=9606 GN=PRDX1 PE=1 SV=1 5.84 3122.8 - 3.38E+07 - - - 0.3571 - 1.804 0.492 - 142.4 1 2 0 0.0004 10 0 0 0 6.25E+08 9.51E+08 - - - 4.3217 0.9997 221125_WJC_METTL3_EV_vs_WT_F02.16749.16749.2 0.00218 16-Oct K.IEVLEEELR.L sp|P15924|DESP_HUMAN 1 1128.6027 3.92 16370 16749 2 1128.602286 565.3086 Desmoplakin OS=Homo sapiens OX=9606 GN=DSP PE=1 SV=3 4.09 3122.8 - 1.22E+07 - - - -0.3261 - 2.041 0.353 - 478.8 1 2 0 -0.0004 9 0 0 0 3.82E+08 9.75E+07 - - - 3.7122 0.9043 221125_WJC_METTL3_EV_vs_WT_F02.16750.16750.2 0.385 18-Aug R.REAALKEDFR.R sp|Q9UH99|SUN2_HUMAN 1 1233.6466 999 16371 16750 2 1233.650063 617.8306 SUN domain-containing protein 2 OS=Homo sapiens OX=9606 GN=SUN2 PE=1 SV=3 6.18 3123 - 1.60E+06 - - - 2.8193 - 1.488 0.206 - 136.9 1 2 1 0.0035 10 0 0 0 4.38E+07 0.00E+00 - - - 1.6708 0.9996 221125_WJC_METTL3_EV_vs_WT_F02.16751.16751.2 0.000778 22-Nov K.GILLVGPPGTGK[136.11].T "sp|Q96TA2|YMEL1_HUMAN,tr|Q96I63|Q96I63_HUMAN,tr|R4GNA5|R4GNA5_HUMAN" 3 1115.6794 2.24 16372 16751 2 1115.679553 558.847 ATP-dependent zinc metalloprotease YME1L1 OS=Homo sapiens OX=9606 GN=YME1L1 PE=1 SV=2 8.75 3123.1 - 931137 - - - 0.1416 - 2.062 0.331 - 263.4 1 2 0 0.0002 12 0 0 0 3.02E+07 1.35E+07 - - - 3.3898 0.9998 221125_WJC_METTL3_EV_vs_WT_F02.16755.16755.3 0.000523 13/44 R.EHALLAYTLGVK[136.11].Q "sp|Q05639|EF1A2_HUMAN,sp|P68104|EF1A1_HUMAN,sp|Q5VTE0|EF1A3_HUMAN,tr|A0A2R8Y488|A0A2R8Y488_HUMAN,tr|A0A7I2V659|A0A7I2V659_HUMAN,tr|A0A7I2V3H3|A0A7I2V3H3_HUMAN,tr|A0A2U3TZH3|A0A2U3TZH3_HUMAN,tr|A0A7I2V5N4|A0A7I2V5N4_HUMAN,tr|A0A087WVQ9|A0A087WVQ9_HUMAN,tr|A0A087WV01|A0A087WV01_HUMAN,tr|A0A2R8Y660|A0A2R8Y660_HUMAN" 11 1321.7485 0.46 16376 16755 3 1321.745993 441.5901 Elongation factor 1-alpha 2 OS=Homo sapiens OX=9606 GN=EEF1A2 PE=1 SV=1 6.85 3123.6 - 468812 - - - -1.9247 - 2.354 0.355 - 258.9 1 2 0 -0.0025 12 0 0 0 3.70E+06 8.10E+06 - - - 4.8702 0.9999 221125_WJC_METTL3_EV_vs_WT_F02.16759.16759.2 8.85E-05 14-Sep K.DVEDMFSR[166.11].F "sp|Q15717|ELAV1_HUMAN,tr|M0R055|M0R055_HUMAN,tr|M0QZR9|M0QZR9_HUMAN" 3 1007.4258 1.28 16378 16759 2 1007.425479 504.7202 ELAV-like protein 1 OS=Homo sapiens OX=9606 GN=ELAVL1 PE=1 SV=2 4.03 3124.1 - 8.21E+06 - - - -0.2849 - 1.555 0.566 - 256.3 1 2 0 -0.0003 8 0 0 0 1.51E+08 1.18E+08 - - - 4.5529 0.9999 221125_WJC_METTL3_EV_vs_WT_F02.16760.16760.2 0.00194 22-Dec R.SGFGEISSPVIR.E "sp|P57740|NU107_HUMAN,tr|G3V1T4|G3V1T4_HUMAN" 2 1247.651 1.96 16379 16760 2 1247.651504 624.8328 Nuclear pore complex protein Nup107 OS=Homo sapiens OX=9606 GN=NUP107 PE=1 SV=1 5.72 3124.2 - 2.75E+06 - - - 0.4032 - 2.39 0.488 - 410.3 1 2 0 0.0005 12 0 0 0 6.52E+07 3.33E+07 - - - 4.9377 0.9997 221125_WJC_METTL3_EV_vs_WT_F02.16761.16761.2 0.00119 14-Sep K.TLEFC[160.03]LSR.E sp|Q92615|LAR4B_HUMAN 1 1024.5012 0.95 16380 16761 2 1024.500854 513.2579 La-related protein 4B OS=Homo sapiens OX=9606 GN=LARP4B PE=1 SV=3 5.66 3124.2 - 4.68E+06 - - - -0.3045 - 1.769 0.377 - 287.7 1 2 0 -0.0003 8 0 0 0 8.32E+07 8.79E+07 - - - 3.5458 0.9954 221125_WJC_METTL3_EV_vs_WT_F02.16763.16763.2 0.0426 14-Jul R.EYIQILER.R "sp|P52948|NUP98_HUMAN,tr|A0A3B3ITD8|A0A3B3ITD8_HUMAN,tr|H7C3P6|H7C3P6_HUMAN" 3 1062.571 1.36 16382 16763 2 1062.573628 532.2928 Nuclear pore complex protein Nup98-Nup96 OS=Homo sapiens OX=9606 GN=NUP98 PE=1 SV=4 4.53 3124.3 - 2.16E+06 - - - 2.5109 - 1.536 0.235 - 240.8 1 2 0 0.0027 8 0 0 0 4.01E+07 2.95E+07 - - - 2.0703 0.9989 221125_WJC_METTL3_EV_vs_WT_F02.16765.16765.2 7.95E-05 20-Nov K.LGTVITPDTWK[136.11].D sp|Q9P021|CRIPT_HUMAN 1 1237.6798 0.54 16384 16765 2 1237.683474 619.8472 Cysteine-rich PDZ-binding protein OS=Homo sapiens OX=9606 GN=CRIPT PE=1 SV=1 5.84 3124.6 - 1.07E+06 - - - 2.9773 - 2.343 0.329 - 338.6 1 2 0 0.0037 11 0 0 0 1.63E+07 3.04E+07 - - - 3.7732 0.9998 221125_WJC_METTL3_EV_vs_WT_F02.16767.16767.2 0.000582 16-Oct R.VEQFLTIAR.R sp|Q9BTC0|DIDO1_HUMAN 1 1075.6026 0.09 16386 16767 2 1075.603392 538.8086 Death-inducer obliterator 1 OS=Homo sapiens OX=9606 GN=DIDO1 PE=1 SV=5 5.97 3124.8 - 758490 - - - 0.741 - 2.006 0.45 - 295.4 1 2 0 0.0008 9 0 0 0 1.02E+07 1.09E+08 - - - 4.3784 0.9997 221125_WJC_METTL3_EV_vs_WT_F02.16769.16769.2 1.79E-06 22-Dec R.IMNTFSVVPSPK.V "sp|P04350|TBB4A_HUMAN,sp|P07437|TBB5_HUMAN,sp|Q13509|TBB3_HUMAN,sp|P68371|TBB4B_HUMAN,tr|M0R2D3|M0R2D3_HUMAN,tr|A0A0B4J269|A0A0B4J269_HUMAN,tr|Q5ST81|Q5ST81_HUMAN,tr|Q5JP53|Q5JP53_HUMAN,tr|M0R042|M0R042_HUMAN,tr|M0QYM7|M0QYM7_HUMAN,tr|G3V2A3|G3V2A3_HUMAN" 11 1318.6955 0.69 16388 16769 2 1318.692658 660.355 Tubulin beta-4A chain OS=Homo sapiens OX=9606 GN=TUBB4A PE=1 SV=2 8.75 3125.1 - 539744 - - - -2.162 - 2.224 0.542 - 516.9 1 2 0 -0.0029 12 0 0 0 1.56E+08 2.27E+08 - - - 5.1464 0.9999 221125_WJC_METTL3_EV_vs_WT_F02.16771.16771.2 2.77E-06 22-Dec R.LNVGGTYFVTTR[166.11].Q sp|Q14681|KCTD2_HUMAN 1 1336.7015 4.25 16389 16771 2 1336.699955 669.358 BTB\POZ domain-containing protein KCTD2 OS=Homo sapiens OX=9606 GN=KCTD2 PE=1 SV=3 8.75 3125.3 - 8.46E+06 - - - -1.1341 - 2.513 0.562 - 478.3 1 2 0 -0.0015 12 0 0 0 5.01E+08 1.18E+08 - - - 5.616 0.9997 221125_WJC_METTL3_EV_vs_WT_F02.16772.16772.2 2.35E-05 16-Sep K.GQVEVFALR.R "sp|Q9BQ67|GRWD1_HUMAN,tr|M0QX71|M0QX71_HUMAN" 2 1017.5607 1.15 16390 16772 2 1017.563084 509.7876 Glutamate-rich WD repeat-containing protein 1 OS=Homo sapiens OX=9606 GN=GRWD1 PE=1 SV=1 6 3125.4 - 4.26E+06 - - - 2.3134 - 2.105 0.531 - 384.1 1 2 0 0.0024 9 0 0 0 5.94E+07 5.17E+07 - - - 5.1156 0.8862 221125_WJC_METTL3_EV_vs_WT_F02.16773.16773.2 0.000367 14-Sep Y.LDVSILGK[136.11].F sp|Q86U44|MTA70_HUMAN 1 851.5208 0.02 16391 16773 2 851.519893 426.7677 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 5.84 3125.4 - 2.89E+06 - - - -1.0287 - 1.92 0.12 - 245.4 1 1 0 -0.0009 8 0 0 0 4.20E+06 2.52E+08 - - - 1.8944 0.9995 221125_WJC_METTL3_EV_vs_WT_F02.16774.16774.2 0.00401 14-Aug R.SSLAEYFK[136.11].D "sp|Q9UBU9|NXF1_HUMAN,tr|E9PIN3|E9PIN3_HUMAN" 2 951.4793 0.88 16392 16774 2 951.478004 476.7469 Nuclear RNA export factor 1 OS=Homo sapiens OX=9606 GN=NXF1 PE=1 SV=1 5.72 3125.5 - 2.27E+06 - - - -1.36 - 1.712 0.369 - 206.5 1 2 0 -0.0013 8 0 0 0 5.13E+07 5.84E+07 - - - 3.3876 0.9911 221125_WJC_METTL3_EV_vs_WT_F02.16776.16776.2 0.122 18-Sep K.VPAVANYIMK[136.11].L "sp|Q9H2P0|ADNP_HUMAN,tr|A0A2R8Y6X0|A0A2R8Y6X0_HUMAN,tr|A0A669KBJ7|A0A669KBJ7_HUMAN" 3 1112.6144 0.57 16394 16776 2 1112.617053 557.3145 Activity-dependent neuroprotector homeobox protein OS=Homo sapiens OX=9606 GN=ADNP PE=1 SV=1 8.56 3125.7 - 945313 - - - 2.4276 - 1.711 0.13 - 171.5 1 2 0 0.0027 10 0 0 0 9.56E+06 1.67E+07 - - - 1.4995 0.9999 221125_WJC_METTL3_EV_vs_WT_F02.16778.16778.2 1.75E-07 22-Dec K.DIPGLTDTTVPR[166.11].R "sp|P62753|RS6_HUMAN,tr|A2A3R5|A2A3R5_HUMAN" 2 1293.6804 0.37 16396 16778 2 1293.68087 647.8475 40S ribosomal protein S6 OS=Homo sapiens OX=9606 GN=RPS6 PE=1 SV=1 4.21 3126 - 613873 - - - 0.3625 - 2.404 0.515 - 558.4 1 2 0 0.0005 12 0 0 0 6.64E+06 1.81E+07 - - - 5.1525 0.9988 221125_WJC_METTL3_EV_vs_WT_F02.16782.16782.2 2.46E-06 14/24 K.IMGVAGGLTNLSK.M "sp|Q8WWY3|PRP31_HUMAN,tr|E7EVX8|E7EVX8_HUMAN,tr|E7EU94|E7EU94_HUMAN,tr|E7ESX0|E7ESX0_HUMAN,tr|E7EN72|E7EN72_HUMAN" 5 1259.6908 1.81 16398 16782 2 1259.696412 630.8527 U4\U6 small nuclear ribonucleoprotein Prp31 OS=Homo sapiens OX=9606 GN=PRPF31 PE=1 SV=2 8.75 3126.4 - 2.73E+06 - - - 4.4884 - 2.624 0.551 - 605.6 1 2 0 0.0057 13 0 0 0 1.65E+08 9.10E+07 - - - 5.5848 0.9993 221125_WJC_METTL3_EV_vs_WT_F02.16783.16783.2 0.000542 20-Oct K.ESIVDVEGVVR[166.11].K "sp|P14868|SYDC_HUMAN,tr|C9JQM9|C9JQM9_HUMAN,tr|C9J7S3|C9J7S3_HUMAN,tr|H7C278|H7C278_HUMAN,tr|C9JLC1|C9JLC1_HUMAN" 5 1210.6433 2.18 16399 16783 2 1210.639872 606.3289 "Aspartate--tRNA ligase, cytoplasmic OS=Homo sapiens OX=9606 GN=DARS1 PE=1 SV=2" 4.14 3126.5 - 3.00E+06 - - - -2.8208 - 2.133 0.42 - 341.7 1 2 0 -0.0034 11 0 0 0 8.17E+07 3.75E+07 - - - 4.1913 0.9997 221125_WJC_METTL3_EV_vs_WT_F02.16785.16785.2 0.0859 13/22 K.GILLVGPPGTGK.T "sp|Q96TA2|YMEL1_HUMAN,tr|Q96I63|Q96I63_HUMAN,tr|R4GNA5|R4GNA5_HUMAN" 3 1107.6652 2.24 16401 16785 2 1107.665316 554.8399 ATP-dependent zinc metalloprotease YME1L1 OS=Homo sapiens OX=9606 GN=YME1L1 PE=1 SV=2 8.75 3126.6 - 1.66E+06 - - - 0.1092 - 2.392 0.284 - 530.1 1 2 0 0.0001 12 0 0 0 3.02E+07 1.35E+07 - - - 3.4333 0.9704 221125_WJC_METTL3_EV_vs_WT_F02.16786.16786.2 0.00472 12-Jul Y.FNIEFTR.C "sp|Q99873|ANM1_HUMAN,tr|E9PKG1|E9PKG1_HUMAN" 2 925.4658 3.91 16402 16786 2 925.46595 463.7402 Protein arginine N-methyltransferase 1 OS=Homo sapiens OX=9606 GN=PRMT1 PE=1 SV=3 6 3126.8 - 1.33E+06 - - - 0.1977 - 1.631 0.33 - 193.2 1 1 0 0.0002 7 0 0 0 1.57E+07 4.01E+06 - - - 3.0284 1 221125_WJC_METTL3_EV_vs_WT_F02.16787.16787.2 2.93E-09 13/24 R.LLVTDMSDAEQYR.S sp|O14929|HAT1_HUMAN 1 1539.7239 0.65 16403 16787 2 1539.722328 770.8692 Histone acetyltransferase type B catalytic subunit OS=Homo sapiens OX=9606 GN=HAT1 PE=1 SV=1 4.03 3126.9 - 1.29E+06 - - - -1.0262 - 2.799 0.658 - 497 1 2 0 -0.0016 13 0 0 0 3.40E+07 5.20E+07 - - - 6.5421 0.9998 221125_WJC_METTL3_EV_vs_WT_F02.16793.16793.2 5.96E-06 26-Oct R.FVTVQTISGTGALR[166.11].L sp|P00505|AATM_HUMAN 1 1458.807 0.95 16409 16793 2 1458.805442 730.4108 "Aspartate aminotransferase, mitochondrial OS=Homo sapiens OX=9606 GN=GOT2 PE=1 SV=3" 9.75 3127.7 - 418896 - - - -1.0666 - 2.212 0.495 - 223.3 1 2 0 -0.0016 14 0 0 0 4.23E+06 4.45E+06 - - - 4.6888 1 221125_WJC_METTL3_EV_vs_WT_F02.16796.16796.2 2.62E-10 14/24 R.LLVTDMSDAEQYR[166.11].S sp|O14929|HAT1_HUMAN 1 1549.7322 0.65 16411 16796 2 1549.731498 775.8734 Histone acetyltransferase type B catalytic subunit OS=Homo sapiens OX=9606 GN=HAT1 PE=1 SV=1 4.03 3128 - 3.85E+06 - - - -0.4388 - 2.882 0.624 - 678 1 2 0 -0.0007 13 0 0 0 3.40E+07 5.20E+07 - - - 6.3663 0.9997 221125_WJC_METTL3_EV_vs_WT_F02.16799.16799.2 0.00193 16-Sep R.GTLDLQVIR[166.11].V sp|Q9BUA3|SPNDC_HUMAN 1 1023.5952 3.05 16413 16799 2 1023.595151 512.8049 Spindlin interactor and repressor of chromatin-binding protein OS=Homo sapiens OX=9606 GN=SPINDOC PE=1 SV=3 5.84 3128.3 - 4.54E+06 - - - -0.0625 - 1.945 0.38 - 283.2 1 2 0 -0.0001 9 0 0 0 1.81E+08 5.92E+07 - - - 3.7723 0.9953 221125_WJC_METTL3_EV_vs_WT_F02.16800.16800.2 0.0603 12-Aug R.QIDFPLR.L "sp|Q9Y6M1|IF2B2_HUMAN,tr|F8W930|F8W930_HUMAN" 2 887.4865 1.67 16414 16800 2 887.484833 444.7505 Insulin-like growth factor 2 mRNA-binding protein 2 OS=Homo sapiens OX=9606 GN=IGF2BP2 PE=1 SV=2 5.84 3128.4 - 2.70E+06 - - - -1.8806 - 1.532 0.171 - 379 1 2 0 -0.0017 7 0 0 0 7.49E+07 4.48E+07 - - - 1.6551 0.9995 221125_WJC_METTL3_EV_vs_WT_F02.16801.16801.2 6.49E-05 16-Aug K.GYGFAEYMK[136.11].K "sp|Q8IY67|RAVR1_HUMAN,tr|E9PAU2|E9PAU2_HUMAN,tr|A0A087WZ13|A0A087WZ13_HUMAN" 3 1072.4779 0.83 16415 16801 2 1072.478751 537.2462 Ribonucleoprotein PTB-binding 1 OS=Homo sapiens OX=9606 GN=RAVER1 PE=1 SV=1 6 3128.4 - 2.16E+06 - - - 0.7767 - 1.49 0.419 - 172.8 1 2 0 0.0008 9 0 0 0 1.82E+08 2.19E+08 - - - 3.2892 0.9999 221125_WJC_METTL3_EV_vs_WT_F02.16805.16805.2 5.42E-06 26-Nov R.SYPDYMYGSPGELR.D sp|P31274|HXC9_HUMAN 1 1633.7083 2.15 16419 16805 2 1633.71048 817.8614 Homeobox protein Hox-C9 OS=Homo sapiens OX=9606 GN=HOXC9 PE=1 SV=3 4.37 3128.9 - 629381 - - - 1.3601 - 2.047 0.611 - 365.9 1 2 0 0.0022 14 0 0 0 5.95E+06 2.76E+06 - - - 5.3509 0.9999 221125_WJC_METTL3_EV_vs_WT_F02.16814.16814.2 0.00239 15/20 K.IGLFGGAGVGK.T "sp|P06576|ATPB_HUMAN,tr|F8W079|F8W079_HUMAN,tr|F8W0P7|F8W0P7_HUMAN,tr|H0YH81|H0YH81_HUMAN" 4 974.5549 1.76 16426 16814 2 974.554916 488.2847 "ATP synthase subunit beta, mitochondrial OS=Homo sapiens OX=9606 GN=ATP5F1B PE=1 SV=3" 8.75 3129.8 - 2.43E+06 - - - 0 - 2.598 0.434 - 554.8 1 2 0 0 11 0 0 0 4.40E+08 2.50E+08 - - - 4.8293 0.9999 221125_WJC_METTL3_EV_vs_WT_F02.16815.16815.2 0.000539 20-Dec K.IGLFGGAGVGK[136.11].T "sp|P06576|ATPB_HUMAN,tr|F8W079|F8W079_HUMAN,tr|F8W0P7|F8W0P7_HUMAN,tr|H0YH81|H0YH81_HUMAN" 4 982.5691 1.76 16427 16815 2 982.56943 492.2918 "ATP synthase subunit beta, mitochondrial OS=Homo sapiens OX=9606 GN=ATP5F1B PE=1 SV=3" 8.75 3129.9 - 1.83E+06 - - - 0.3196 - 2.441 0.484 - 308.6 1 2 0 0.0003 11 0 0 0 4.39E+08 2.50E+08 - - - 5.0299 0.9989 221125_WJC_METTL3_EV_vs_WT_F02.16818.16818.3 0.00267 Nov-40 R.IYSHSLLPVLR[166.11].S sp|P22102|PUR2_HUMAN 1 1306.7637 0.77 16430 16818 3 1306.764371 436.5952 Trifunctional purine biosynthetic protein adenosine-3 OS=Homo sapiens OX=9606 GN=GART PE=1 SV=1 8.75 3130.2 - 799202 - - - 0.5311 - 2.02 0.24 - 196.3 1 2 0 0.0007 11 0 0 0 3.36E+07 4.36E+07 - - - 3.213 0.999 221125_WJC_METTL3_EV_vs_WT_F02.16823.16823.2 0.0654 14-Aug R.SLDINAFR[166.11].K "sp|Q8WU79|SMAP2_HUMAN,tr|A0A087WV97|A0A087WV97_HUMAN,tr|X6RCC3|X6RCC3_HUMAN" 3 944.4955 1.7 16434 16823 2 944.495472 473.255 Stromal membrane-associated protein 2 OS=Homo sapiens OX=9606 GN=SMAP2 PE=1 SV=1 5.55 3130.8 - 5.43E+06 - - - -0.0307 - 1.565 0.263 - 230.6 1 2 0 0 8 0 0 0 2.09E+08 1.23E+08 - - - 2.3343 0.9868 221125_WJC_METTL3_EV_vs_WT_F02.16825.16825.2 0.00743 18-Oct K.LLHHLSDLAL.T "sp|Q86U44|MTA70_HUMAN,tr|B4E349|B4E349_HUMAN,tr|F5H6D8|F5H6D8_HUMAN,tr|H0YFV6|H0YFV6_HUMAN,tr|B4DTN4|B4DTN4_HUMAN" 5 1130.6448 - 16435 16825 2 1130.644845 566.3297 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 5.97 3131.1 - 2.18E+07 - - - 0.0451 - 1.942 0.412 - 273.9 1 1 0 0.0001 10 0 0 0 - - - - - 3.9367 0.9998 221125_WJC_METTL3_EV_vs_WT_F02.16826.16826.2 0.0274 20-Nov K.APSYLEISSMR.R "sp|P78347|GTF2I_HUMAN,tr|A0A494C1K3|A0A494C1K3_HUMAN" 2 1252.6122 1.49 16436 16826 2 1252.611855 627.3134 General transcription factor II-I OS=Homo sapiens OX=9606 GN=GTF2I PE=1 SV=2 6.05 3131.1 - 1.85E+07 - - - -0.2539 - 2.032 0.396 - 569.2 1 2 0 -0.0003 11 0 0 0 8.64E+08 5.79E+08 - - - 3.8838 0.9999 221125_WJC_METTL3_EV_vs_WT_F02.16828.16828.2 0.000115 13/20 K.APSYLEISSMR[166.11].R "sp|P78347|GTF2I_HUMAN,tr|A0A494C1K3|A0A494C1K3_HUMAN" 2 1262.6204 1.49 16438 16828 2 1262.619904 632.3175 General transcription factor II-I OS=Homo sapiens OX=9606 GN=GTF2I PE=1 SV=2 6.05 3131.2 - 1.43E+07 - - - -0.4269 - 2.513 0.505 - 882 1 2 0 -0.0005 11 0 0 0 8.64E+08 5.79E+08 - - - 5.2636 0.9998 221125_WJC_METTL3_EV_vs_WT_F02.16829.16829.2 1.58E-05 16-Sep K.GYGFAEYMK.K "sp|Q8IY67|RAVR1_HUMAN,tr|E9PAU2|E9PAU2_HUMAN,tr|A0A087WZ13|A0A087WZ13_HUMAN" 3 1064.4637 0.83 16439 16829 2 1064.46302 533.2391 Ribonucleoprotein PTB-binding 1 OS=Homo sapiens OX=9606 GN=RAVER1 PE=1 SV=1 6 3131.2 - 7.47E+06 - - - -0.6557 - 1.762 0.529 - 237.7 1 2 0 -0.0007 9 0 0 0 1.82E+08 2.19E+08 - - - 4.5867 0.9999 221125_WJC_METTL3_EV_vs_WT_F02.16830.16830.2 3.34E-05 18-Nov K.VISVDELEYR.Q "sp|Q9NRA8|4ET_HUMAN,tr|B1AKL4|B1AKL4_HUMAN" 2 1221.6241 1.11 16440 16830 2 1221.623551 611.8193 Eukaryotic translation initiation factor 4E transporter OS=Homo sapiens OX=9606 GN=EIF4ENIF1 PE=1 SV=2 4.14 3131.3 - 4.37E+06 - - - -0.4641 - 2.065 0.507 - 442.2 1 2 0 -0.0006 10 0 0 0 1.79E+08 1.61E+08 - - - 4.8096 0.9999 221125_WJC_METTL3_EV_vs_WT_F02.16831.16831.2 5.48E-06 16-Sep R.VFFYNPTTR[166.11].L "sp|O14776|TCRG1_HUMAN,tr|A0A7P0T8N8|A0A7P0T8N8_HUMAN,tr|G3V220|G3V220_HUMAN" 3 1153.5796 0.83 16441 16831 2 1153.579124 577.7971 Transcription elongation regulator 1 OS=Homo sapiens OX=9606 GN=TCERG1 PE=1 SV=2 8.72 3131.3 - 2.11E+06 - - - -0.3823 - 1.781 0.522 - 296.5 1 2 0 -0.0004 9 0 0 0 5.00E+07 6.04E+07 - - - 4.5662 0.9189 221125_WJC_METTL3_EV_vs_WT_F02.16835.16835.2 3.77 14-Jun K.NIPIPTLK[136.11].D "sp|Q9NYL9|TMOD3_HUMAN,sp|P28289|TMOD1_HUMAN,tr|H0YKU1|H0YKU1_HUMAN,tr|H0YNJ8|H0YNJ8_HUMAN" 4 902.5681 1.12 16445 16835 2 902.567488 452.2913 Tropomodulin-3 OS=Homo sapiens OX=9606 GN=TMOD3 PE=1 SV=1 8.75 3131.7 - 996891 - - - -0.6271 - 0.962 0.048 - 68.2 1 2 0 -0.0006 8 0 0 0 2.72E+07 2.43E+07 - - - -0.7215 0.9981 221125_WJC_METTL3_EV_vs_WT_F02.16836.16836.2 0.0179 12-Aug R.ESFLNLR.K sp|Q9NVK5|FGOP2_HUMAN 1 877.4658 11.93 16446 16836 2 877.465322 439.7402 FGFR1 oncogene partner 2 OS=Homo sapiens OX=9606 GN=FGFR1OP2 PE=1 SV=1 6.1 3131.9 - 739636 - - - -0.5071 - 1.605 0.178 - 210.7 1 2 0 -0.0004 7 0 0 0 1.36E+07 1.14E+06 - - - 1.8547 1 221125_WJC_METTL3_EV_vs_WT_F02.16841.16841.2 8.41E-09 20-Dec K.EDGAISTIVLR[166.11].G sp|P50990|TCPQ_HUMAN 1 1182.6484 0.42 16449 16841 2 1182.647146 592.3315 T-complex protein 1 subunit theta OS=Homo sapiens OX=9606 GN=CCT8 PE=1 SV=4 4.37 3132.5 - 8.95E+06 - - - -1.0367 - 2.532 0.646 - 503.6 1 2 0 -0.0012 11 0 0 0 2.87E+08 6.82E+08 - - - 6.3252 1 221125_WJC_METTL3_EV_vs_WT_F02.16843.16843.2 5.45E-09 15/26 K.MVAYLQDSALDDER.L "sp|Q6Y7W6|GGYF2_HUMAN,tr|A0A7I2V3H7|A0A7I2V3H7_HUMAN,tr|I1E4Y6|I1E4Y6_HUMAN,tr|A0A7I2V516|A0A7I2V516_HUMAN,tr|A0A7I2V3H0|A0A7I2V3H0_HUMAN,tr|C9JHW1|C9JHW1_HUMAN,tr|A0A7I2V361|A0A7I2V361_HUMAN,tr|E7ESB6|E7ESB6_HUMAN" 8 1624.7403 3.47 16451 16843 2 1624.739656 813.3774 GRB10-interacting GYF protein 2 OS=Homo sapiens OX=9606 GN=GIGYF2 PE=1 SV=1 3.84 3132.7 - 2.03E+06 - - - -0.3884 - 3.356 0.706 - 993.3 1 2 0 -0.0006 14 0 0 0 8.07E+07 2.32E+07 - - - 7.2936 0.9996 221125_WJC_METTL3_EV_vs_WT_F02.16845.16845.3 0.00189 Dec-40 K.APSYLEISSMR.R "sp|P78347|GTF2I_HUMAN,tr|A0A494C1K3|A0A494C1K3_HUMAN" 2 1252.6122 1.67 16453 16845 3 1252.610508 418.5447 General transcription factor II-I OS=Homo sapiens OX=9606 GN=GTF2I PE=1 SV=2 6.05 3133 - 923680 - - - -1.3292 - 1.874 0.341 - 265.3 1 2 0 -0.0017 11 0 0 0 1.25E+07 7.48E+06 - - - 4.1256 0.9988 221125_WJC_METTL3_EV_vs_WT_F02.16849.16849.2 0.00972 14-Jun K.LTVNDFVR.D "sp|O75746|CMC1_HUMAN,sp|Q9UJS0|CMC2_HUMAN" 2 962.5185 0.81 16457 16849 2 962.51691 482.2665 Calcium-binding mitochondrial carrier protein Aralar1 OS=Homo sapiens OX=9606 GN=SLC25A12 PE=1 SV=2 5.84 3133.5 - 744416 - - - -1.6841 - 1.623 0.321 - 117.1 2 2 0 -0.0016 8 0 0 0 2.37E+07 2.92E+07 - - - 2.7375 0.9941 221125_WJC_METTL3_EV_vs_WT_F02.16851.16851.2 1.22E-07 22-Oct M.VNYYTSVTPVLR.G "sp|P26599|PTBP1_HUMAN,tr|A0A6Q8PEX4|A0A6Q8PEX4_HUMAN,tr|A0A0U1RRM4|A0A0U1RRM4_HUMAN,tr|A6NLN1|A6NLN1_HUMAN,tr|K7EKJ7|K7EKJ7_HUMAN,tr|K7ES59|K7ES59_HUMAN,tr|A0A7I2V4H6|A0A7I2V4H6_HUMAN,tr|A0A7I2V621|A0A7I2V621_HUMAN" 8 1410.7507 0.3 16459 16851 2 1410.751217 706.3826 Polypyrimidine tract-binding protein 1 OS=Homo sapiens OX=9606 GN=PTBP1 PE=1 SV=1 8.56 3133.7 - 412492 - - - 0.3551 - 2.3 0.557 - 352.9 1 1 0 0.0005 12 0 0 0 5.82E+06 1.94E+07 - - - 5.3464 0.9999 221125_WJC_METTL3_EV_vs_WT_F02.16852.16852.2 5.34E-08 13/26 K.MMADEALGSGLVSR[166.11].V sp|Q13011|ECH1_HUMAN 1 1445.6882 0.35 16460 16852 2 1445.687042 723.8514 "Delta(3,5)-Delta(2,4)-dienoyl-CoA isomerase, mitochondrial OS=Homo sapiens OX=9606 GN=ECH1 PE=1 SV=2" 4.37 3133.8 - 355416 - - - -0.8045 - 2.283 0.556 - 260.1 1 2 0 -0.0012 14 0 0 0 8.40E+06 2.40E+07 - - - 5.2188 0.9995 221125_WJC_METTL3_EV_vs_WT_F02.16854.16854.2 0.278 14-Sep R.SLDINAFR.K "sp|Q8WU79|SMAP2_HUMAN,tr|A0A087WV97|A0A087WV97_HUMAN,tr|X6RCC3|X6RCC3_HUMAN" 3 934.4872 1.7 16461 16854 2 934.486629 468.2509 Stromal membrane-associated protein 2 OS=Homo sapiens OX=9606 GN=SMAP2 PE=1 SV=1 5.55 3134.1 - 1.80E+07 - - - -0.6442 - 1.778 0.315 - 272.2 1 2 0 -0.0006 8 0 0 0 2.09E+08 1.23E+08 - - - 3.1031 0.9999 221125_WJC_METTL3_EV_vs_WT_F02.16855.16855.2 0.00548 18-Nov K.ISDSVLVDIK[136.11].D "sp|P48643|TCPE_HUMAN,tr|E9PCA1|E9PCA1_HUMAN,tr|B7ZAR1|B7ZAR1_HUMAN,tr|E7ENZ3|E7ENZ3_HUMAN" 4 1095.6267 0.63 16462 16855 2 1095.627066 548.8206 T-complex protein 1 subunit epsilon OS=Homo sapiens OX=9606 GN=CCT5 PE=1 SV=1 4.21 3134.1 - 7.79E+06 - - - 0.3423 - 2.554 0.414 - 272.6 1 2 0 0.0004 10 0 0 0 1.18E+08 1.86E+08 - - - 4.716 0.9999 221125_WJC_METTL3_EV_vs_WT_F02.16856.16856.2 0.000307 16-Dec K.LGEWVGLC[160.03]K.L sp|P25398|RS12_HUMAN 1 1060.5376 1.63 16463 16856 2 1060.537409 531.2761 40S ribosomal protein S12 OS=Homo sapiens OX=9606 GN=RPS12 PE=1 SV=3 5.99 3134.1 - 2.70E+07 - - - -0.1348 - 2.292 0.501 - 519.8 1 2 0 -0.0001 9 0 0 0 1.06E+09 6.48E+08 - - - 5.1409 0.9998 221125_WJC_METTL3_EV_vs_WT_F02.16857.16857.2 0.0118 16-Nov K.LGEWVGLC[160.03]K[136.11].L sp|P25398|RS12_HUMAN 1 1068.5518 1.61 16464 16857 2 1068.551801 535.2832 40S ribosomal protein S12 OS=Homo sapiens OX=9606 GN=RPS12 PE=1 SV=3 5.99 3134.2 - 2.00E+07 - - - 0.0459 - 2.333 0.373 - 449.3 1 2 0 0 9 0 0 0 1.06E+09 6.63E+08 - - - 4.2468 0.9998 221125_WJC_METTL3_EV_vs_WT_F02.16858.16858.2 6.34E-06 18-Sep R.LITLEEEMTK.Y "sp|P07237|PDIA1_HUMAN,tr|A0A7P0TA97|A0A7P0TA97_HUMAN,tr|A0A7P0T8C0|A0A7P0T8C0_HUMAN,tr|H7BZ94|H7BZ94_HUMAN,tr|A0A7P0TA71|A0A7P0TA71_HUMAN,tr|I3L4M2|I3L4M2_HUMAN,tr|A0A7P0T9D6|A0A7P0T9D6_HUMAN,tr|A0A7P0T9K9|A0A7P0T9K9_HUMAN,tr|H0Y3Z3|H0Y3Z3_HUMAN,tr|A0A7P0TA35|A0A7P0TA35_HUMAN,tr|I3L514|I3L514_HUMAN,tr|A0A7P0TB26|A0A7P0TB26_HUMAN,tr|A0A7P0T9U6|A0A7P0T9U6_HUMAN,tr|I3L0S0|I3L0S0_HUMAN,tr|I3L3P5|I3L3P5_HUMAN,tr|A0A7P0T8J3|A0A7P0T8J3_HUMAN,tr|A0A7P0T8X1|A0A7P0T8X1_HUMAN" 17 1205.6213 0.82 16465 16858 2 1205.619909 603.8179 Protein disulfide-isomerase OS=Homo sapiens OX=9606 GN=P4HB PE=1 SV=3 4.25 3134.2 - 6.19E+06 - - - -1.1878 - 1.83 0.527 - 208.8 1 2 0 -0.0014 10 0 0 0 8.28E+07 1.01E+08 - - - 4.6198 0.9994 221125_WJC_METTL3_EV_vs_WT_F02.16861.16861.2 8.57E-05 20-Dec K.AMVEYEIDLQK[136.11].M sp|P09874|PARP1_HUMAN 1 1345.6679 1.03 16468 16861 2 1345.663603 673.8412 Poly [ADP-ribose] polymerase 1 OS=Homo sapiens OX=9606 GN=PARP1 PE=1 SV=4 4.14 3134.5 - 1.67E+06 - - - -3.1962 - 2.475 0.48 - 552.9 1 2 0 -0.0043 11 0 0 0 6.44E+07 6.23E+07 - - - 5.0365 0.9975 221125_WJC_METTL3_EV_vs_WT_F02.16862.16862.2 0.0805 16-Sep R.GFFLSAAGK[136.11].F "sp|Q9BSV6|SEN34_HUMAN,tr|A0A590UJ73|A0A590UJ73_HUMAN,tr|E7EQB3|E7EQB3_HUMAN,tr|A0A0G2JNK5|A0A0G2JNK5_HUMAN,tr|A0A0G2JNL0|A0A0G2JNL0_HUMAN,tr|A0A590UJW4|A0A590UJW4_HUMAN,tr|B0V3J0|B0V3J0_HUMAN" 7 904.4898 1.69 16469 16862 2 904.487961 453.2522 tRNA-splicing endonuclease subunit Sen34 OS=Homo sapiens OX=9606 GN=TSEN34 PE=1 SV=1 8.75 3134.5 - 1.34E+06 - - - -2.0365 - 1.621 0.245 - 222.9 1 2 0 -0.0018 9 0 0 0 2.78E+07 1.64E+07 - - - 2.2475 0.8082 221125_WJC_METTL3_EV_vs_WT_F02.16863.16863.2 0.854 22-Jul R.NLDFLK[136.11]AVDTNR[166.11].A sp|Q6UX71|PXDC2_HUMAN 1 1422.7586 0.001 16470 16863 2 1422.755923 712.3866 Plexin domain-containing protein 2 OS=Homo sapiens OX=9606 GN=PLXDC2 PE=1 SV=1 5.96 3134.7 - 1.24E+06 - - - -1.8802 - 1.465 0.073 - 124.9 1 2 1 -0.0027 12 0 0 0 0.00E+00 4.93E+07 - - - 0.5841 0.9999 221125_WJC_METTL3_EV_vs_WT_F02.16864.16864.2 0.000241 20-Nov K.AMVEYEIDLQK.M sp|P09874|PARP1_HUMAN 1 1337.6537 1.04 16471 16864 2 1337.654121 669.8341 Poly [ADP-ribose] polymerase 1 OS=Homo sapiens OX=9606 GN=PARP1 PE=1 SV=4 4.14 3134.8 - 1.19E+06 - - - 0.3117 - 2.416 0.469 - 454.5 1 2 0 0.0004 11 0 0 0 6.51E+07 6.24E+07 - - - 4.8912 1 221125_WJC_METTL3_EV_vs_WT_F02.16865.16865.2 5.85E-07 15/26 K.MVAYLQDSALDDER[166.11].L "sp|Q6Y7W6|GGYF2_HUMAN,tr|A0A7I2V3H7|A0A7I2V3H7_HUMAN,tr|I1E4Y6|I1E4Y6_HUMAN,tr|A0A7I2V516|A0A7I2V516_HUMAN,tr|A0A7I2V3H0|A0A7I2V3H0_HUMAN,tr|C9JHW1|C9JHW1_HUMAN,tr|A0A7I2V361|A0A7I2V361_HUMAN,tr|E7ESB6|E7ESB6_HUMAN" 8 1634.7486 3.47 16472 16865 2 1634.745771 818.3816 GRB10-interacting GYF protein 2 OS=Homo sapiens OX=9606 GN=GIGYF2 PE=1 SV=1 3.84 3134.9 - 1.13E+06 - - - -1.7042 - 3.188 0.657 - 937.7 1 2 0 -0.0028 14 0 0 0 8.07E+07 2.32E+07 - - - 6.8022 0.9945 221125_WJC_METTL3_EV_vs_WT_F02.16868.16868.2 0.0792 12-Jul R.QIDFPLR[166.11].L "sp|Q9Y6M1|IF2B2_HUMAN,tr|F8W930|F8W930_HUMAN" 2 897.4948 1.67 16474 16868 2 897.493199 449.7547 Insulin-like growth factor 2 mRNA-binding protein 2 OS=Homo sapiens OX=9606 GN=IGF2BP2 PE=1 SV=2 5.84 3135.2 - 2.63E+06 - - - -1.7527 - 1.247 0.234 - 167.3 1 2 0 -0.0016 7 0 0 0 7.49E+07 4.48E+07 - - - 1.4683 0.9995 221125_WJC_METTL3_EV_vs_WT_F02.16872.16872.2 0.00288 14-Aug R.GFTLVGMK.M "sp|O00746|NDKM_HUMAN,tr|Q4TT34|Q4TT34_HUMAN,tr|A0A087WVT9|A0A087WVT9_HUMAN,tr|H0Y6J0|H0Y6J0_HUMAN,tr|F2Z2X0|F2Z2X0_HUMAN" 5 851.4575 1.81 16477 16872 2 851.456943 426.736 "Nucleoside diphosphate kinase, mitochondrial OS=Homo sapiens OX=9606 GN=NME4 PE=1 SV=1" 8.75 3135.6 - 8.54E+06 - - - -0.6659 - 1.416 0.396 - 221.8 1 2 0 -0.0006 8 0 0 0 9.70E+07 5.37E+07 - - - 3.0147 0.9999 221125_WJC_METTL3_EV_vs_WT_F02.16873.16873.2 7.18E-07 22-Dec K.YGEYFPGTGDLR.D "sp|Q92769|HDAC2_HUMAN,sp|Q13547|HDAC1_HUMAN,tr|Q5TEE2|Q5TEE2_HUMAN" 3 1373.6252 1.61 16478 16873 2 1373.623232 687.8199 Histone deacetylase 2 OS=Homo sapiens OX=9606 GN=HDAC2 PE=1 SV=2 4.37 3135.7 - 1.92E+06 - - - -1.4189 - 2.38 0.586 - 418.8 1 2 0 -0.0019 12 0 0 0 3.99E+08 2.48E+08 - - - 5.6501 0.9999 221125_WJC_METTL3_EV_vs_WT_F02.16874.16874.2 7.90E-05 13/22 K.YGEYFPGTGDLR[166.11].D "sp|Q92769|HDAC2_HUMAN,sp|Q13547|HDAC1_HUMAN,tr|Q5TEE2|Q5TEE2_HUMAN" 3 1383.6335 1.61 16479 16874 2 1383.632854 692.824 Histone deacetylase 2 OS=Homo sapiens OX=9606 GN=HDAC2 PE=1 SV=2 4.37 3135.8 - 1.40E+06 - - - -0.4315 - 2.486 0.566 - 563.1 1 2 0 -0.0006 12 0 0 0 3.99E+08 2.48E+08 - - - 5.6174 0.9989 221125_WJC_METTL3_EV_vs_WT_F02.16876.16876.3 0.00466 Oct-40 K.APSYLEISSMR[166.11].R "sp|P78347|GTF2I_HUMAN,tr|A0A494C1K3|A0A494C1K3_HUMAN" 2 1262.6204 1.67 16481 16876 3 1262.618245 421.8808 General transcription factor II-I OS=Homo sapiens OX=9606 GN=GTF2I PE=1 SV=2 6.05 3136.1 - 984260 - - - -1.7408 - 1.978 0.275 - 150.8 1 2 0 -0.0022 11 0 0 0 1.25E+07 7.48E+06 - - - 3.5431 0.9999 221125_WJC_METTL3_EV_vs_WT_F02.16881.16881.2 7.69E-07 20-Nov K.EDGAISTIVLR.G sp|P50990|TCPQ_HUMAN 1 1172.6401 0.42 16484 16881 2 1172.640138 587.3273 T-complex protein 1 subunit theta OS=Homo sapiens OX=9606 GN=CCT8 PE=1 SV=4 4.37 3136.7 - 1.87E+07 - - - 0.0307 - 2.285 0.578 - 429 1 2 0 0 11 0 0 0 2.88E+08 6.82E+08 - - - 5.5456 0.9999 221125_WJC_METTL3_EV_vs_WT_F02.16882.16882.2 3.32E-05 20-Oct K.FVNWQVDGEYR.G "sp|O96008|TOM40_HUMAN,tr|K7EKG4|K7EKG4_HUMAN,tr|K7EJ57|K7EJ57_HUMAN" 3 1411.6521 1.22 16485 16882 2 1411.652276 706.8333 Mitochondrial import receptor subunit TOM40 homolog OS=Homo sapiens OX=9606 GN=TOMM40 PE=1 SV=1 4.37 3136.8 - 1.65E+06 - - - 0.1502 - 2.192 0.541 - 397.7 1 2 0 0.0002 11 0 0 0 4.26E+07 3.49E+07 - - - 5.1599 0.9999 221125_WJC_METTL3_EV_vs_WT_F02.16883.16883.2 4.18E-05 18-Oct R.QAEVLAEFER.R sp|O43172|PRP4_HUMAN 1 1190.5932 2.16 16486 16883 2 1190.593325 596.3039 U4\U6 small nuclear ribonucleoprotein Prp4 OS=Homo sapiens OX=9606 GN=PRPF4 PE=1 SV=2 4.25 3136.8 - 1.47E+07 - - - 0.1453 - 2.02 0.509 - 305.3 1 2 0 0.0002 10 0 0 0 1.78E+08 8.23E+07 - - - 4.763 0.9994 221125_WJC_METTL3_EV_vs_WT_F02.16884.16884.2 0.000654 16-Aug R.VFFYNPTTR.L "sp|O14776|TCRG1_HUMAN,tr|A0A7P0T8N8|A0A7P0T8N8_HUMAN,tr|G3V220|G3V220_HUMAN" 3 1143.5713 0.83 16487 16884 2 1143.568729 572.7929 Transcription elongation regulator 1 OS=Homo sapiens OX=9606 GN=TCERG1 PE=1 SV=2 8.72 3136.9 - 2.31E+06 - - - -2.2438 - 1.649 0.459 - 231.5 1 2 0 -0.0026 9 0 0 0 5.06E+07 6.06E+07 - - - 3.8774 0.9999 221125_WJC_METTL3_EV_vs_WT_F02.16886.16886.2 7.89E-06 22-Nov R.LGFTPSVTIEQR[166.11].R "sp|Q9Y4A5|TRRAP_HUMAN,tr|H0Y4W2|H0Y4W2_HUMAN,tr|F2Z2U4|F2Z2U4_HUMAN" 3 1356.7277 0.86 16489 16886 2 1356.726907 679.3711 Transformation\transcription domain-associated protein OS=Homo sapiens OX=9606 GN=TRRAP PE=1 SV=3 6 3137.1 - 1.14E+06 - - - -0.5734 - 2.608 0.455 - 292.4 1 2 0 -0.0008 12 0 0 0 1.50E+07 1.74E+07 - - - 4.9236 0.9993 221125_WJC_METTL3_EV_vs_WT_F02.16887.16887.2 0.247 18-Nov K.VSTLPAITLK[136.11].L "sp|P07339|CATD_HUMAN,tr|A0A1B0GW44|A0A1B0GW44_HUMAN,tr|A0A1B0GVD5|A0A1B0GVD5_HUMAN,tr|A0A1B0GV23|A0A1B0GV23_HUMAN,tr|C9JH19|C9JH19_HUMAN,tr|H7C469|H7C469_HUMAN,tr|A0A1B0GWE8|A0A1B0GWE8_HUMAN,tr|A0A1B0GU03|A0A1B0GU03_HUMAN,tr|A0A1B0GVP3|A0A1B0GVP3_HUMAN,tr|A0A1B0GU92|A0A1B0GU92_HUMAN,tr|F8W787|F8W787_HUMAN" 11 1049.6576 6.7 16490 16887 2 1049.656171 525.8361 Cathepsin D OS=Homo sapiens OX=9606 GN=CTSD PE=1 SV=1 8.72 3137.2 - 878712 - - - -1.3585 - 1.987 0.277 - 313.6 1 2 0 -0.0014 10 0 0 0 2.12E+08 3.17E+07 - - - 3.0031 0.997 221125_WJC_METTL3_EV_vs_WT_F02.16889.16889.3 0.0697 Sep-40 K.EDGAISTIVLR[166.11].G sp|P50990|TCPQ_HUMAN 1 1182.6484 0.38 16492 16889 3 1182.646877 395.2234 T-complex protein 1 subunit theta OS=Homo sapiens OX=9606 GN=CCT8 PE=1 SV=4 4.37 3137.5 - 457425 - - - -1.2641 - 1.652 0.24 - 82.5 1 2 0 -0.0015 11 0 0 0 2.67E+06 7.10E+06 - - - 2.6414 0.9999 221125_WJC_METTL3_EV_vs_WT_F02.16890.16890.2 1.01E-09 14/22 R.SSLDNIEMAYAR.Q "sp|Q8N1F7|NUP93_HUMAN,tr|H3BP95|H3BP95_HUMAN,tr|H3BVG0|H3BVG0_HUMAN,tr|H3BMX0|H3BMX0_HUMAN" 4 1368.6344 0.94 16493 16890 2 1368.635135 685.3245 Nuclear pore complex protein Nup93 OS=Homo sapiens OX=9606 GN=NUP93 PE=1 SV=2 4.37 3137.6 - 405225 - - - 0.5626 - 2.746 0.516 - 776 1 2 0 0.0008 12 0 0 0 1.47E+07 1.56E+07 - - - 5.5098 0.9995 221125_WJC_METTL3_EV_vs_WT_F02.16892.16892.2 0.00166 18-Sep R.LITLEEEMTK[136.11].Y "sp|P07237|PDIA1_HUMAN,tr|A0A7P0TA97|A0A7P0TA97_HUMAN,tr|A0A7P0T8C0|A0A7P0T8C0_HUMAN,tr|H7BZ94|H7BZ94_HUMAN,tr|A0A7P0TA71|A0A7P0TA71_HUMAN,tr|I3L4M2|I3L4M2_HUMAN,tr|A0A7P0T9D6|A0A7P0T9D6_HUMAN,tr|A0A7P0T9K9|A0A7P0T9K9_HUMAN,tr|H0Y3Z3|H0Y3Z3_HUMAN,tr|A0A7P0TA35|A0A7P0TA35_HUMAN,tr|I3L514|I3L514_HUMAN,tr|A0A7P0TB26|A0A7P0TB26_HUMAN,tr|A0A7P0T9U6|A0A7P0T9U6_HUMAN,tr|I3L0S0|I3L0S0_HUMAN,tr|I3L3P5|I3L3P5_HUMAN,tr|A0A7P0T8J3|A0A7P0T8J3_HUMAN,tr|A0A7P0T8X1|A0A7P0T8X1_HUMAN" 17 1213.6355 0.82 16494 16892 2 1213.634254 607.825 Protein disulfide-isomerase OS=Homo sapiens OX=9606 GN=P4HB PE=1 SV=3 4.25 3137.8 - 5.38E+06 - - - -1.0605 - 1.718 0.352 - 193.1 1 2 0 -0.0013 10 0 0 0 8.28E+07 1.01E+08 - - - 3.151 0.9997 221125_WJC_METTL3_EV_vs_WT_F02.16894.16894.2 0.00309 18-Oct K.VSTLPAITLK.L "sp|P07339|CATD_HUMAN,tr|A0A1B0GW44|A0A1B0GW44_HUMAN,tr|A0A1B0GVD5|A0A1B0GVD5_HUMAN,tr|A0A1B0GV23|A0A1B0GV23_HUMAN,tr|C9JH19|C9JH19_HUMAN,tr|H7C469|H7C469_HUMAN,tr|A0A1B0GWE8|A0A1B0GWE8_HUMAN,tr|A0A1B0GU03|A0A1B0GU03_HUMAN,tr|A0A1B0GVP3|A0A1B0GVP3_HUMAN,tr|A0A1B0GU92|A0A1B0GU92_HUMAN,tr|F8W787|F8W787_HUMAN" 11 1041.6434 5.82 16496 16894 2 1041.643728 521.829 Cathepsin D OS=Homo sapiens OX=9606 GN=CTSD PE=1 SV=1 8.72 3137.9 - 5.15E+06 - - - 0.3178 - 1.935 0.385 - 341.1 1 2 0 0.0003 10 0 0 0 1.07E+08 1.83E+07 - - - 3.7271 0.9975 221125_WJC_METTL3_EV_vs_WT_F02.16897.16897.2 0.0323 16-Jul R.DLPPLVVQR.E sp|Q6QNY0|BL1S3_HUMAN 1 1035.6077 1.67 16499 16897 2 1035.608172 518.8111 Biogenesis of lysosome-related organelles complex 1 subunit 3 OS=Homo sapiens OX=9606 GN=BLOC1S3 PE=1 SV=1 5.84 3138.1 - 1.04E+06 - - - 0.4751 - 1.262 0.266 - 157.3 1 2 0 0.0005 9 0 0 0 1.39E+07 8.32E+06 - - - 1.6787 0.9907 221125_WJC_METTL3_EV_vs_WT_F02.16900.16900.2 0.193 14-May K.NVPYVFVR.S "sp|P55769|NH2L1_HUMAN,tr|B1AHD1|B1AHD1_HUMAN,tr|A0A3B3ISH1|A0A3B3ISH1_HUMAN,tr|A0A3B3IUA2|A0A3B3IUA2_HUMAN,tr|A0A3B3IRU2|A0A3B3IRU2_HUMAN" 5 992.5444 1 16501 16900 2 992.545955 497.2795 NHP2-like protein 1 OS=Homo sapiens OX=9606 GN=SNU13 PE=1 SV=3 8.75 3138.4 - 500548 - - - 1.616 - 1.348 0.242 - 49.7 27 2 0 0.0016 8 0 0 0 3.84E+07 3.83E+07 - - - 1.0891 0.9077 221125_WJC_METTL3_EV_vs_WT_F02.16902.16902.2 0.0407 16-Aug R.AVFPSIVGR.P "sp|Q6S8J3|POTEE_HUMAN,sp|P63261|ACTG_HUMAN,sp|P68133|ACTS_HUMAN,sp|P62736|ACTA_HUMAN,sp|P68032|ACTC_HUMAN,sp|P60709|ACTB_HUMAN,sp|P63267|ACTH_HUMAN,sp|A5A3E0|POTEF_HUMAN,sp|P0CG38|POTEI_HUMAN,tr|A0A804GS07|A0A804GS07_HUMAN,tr|I3L3I0|I3L3I0_HUMAN,tr|G5E9R0|G5E9R0_HUMAN,tr|E7EVS6|E7EVS6_HUMAN,tr|B8ZZJ2|B8ZZJ2_HUMAN,tr|J3KT65|J3KT65_HUMAN,tr|I3L3R2|I3L3R2_HUMAN,tr|K7EM38|K7EM38_HUMAN,tr|F6QUT6|F6QUT6_HUMAN,tr|C9JTX5|C9JTX5_HUMAN,tr|A0A6Q8PH58|A0A6Q8PH58_HUMAN,tr|F6UVQ4|F6UVQ4_HUMAN,tr|F8WB63|F8WB63_HUMAN,tr|I3L1U9|I3L1U9_HUMAN,tr|A0A2R8Y793|A0A2R8Y793_HUMAN,tr|I3L4N8|I3L4N8_HUMAN,tr|C9JUM1|C9JUM1_HUMAN,tr|F8WCH0|F8WCH0_HUMAN,tr|C9JZR7|C9JZR7_HUMAN,tr|C9JFL5|C9JFL5_HUMAN,tr|A0A2R8YGF8|A0A2R8YGF8_HUMAN,tr|A6NL76|A6NL76_HUMAN" 31 944.5444 1 16502 16902 2 944.544034 473.2795 POTE ankyrin domain family member E OS=Homo sapiens OX=9606 GN=POTEE PE=2 SV=3 9.79 3138.7 - 6.89E+06 - - - -0.3356 - 1.338 0.277 - 227.3 1 1 0 -0.0003 9 0 0 0 4.02E+08 4.02E+08 - - - 1.9292 0.9993 221125_WJC_METTL3_EV_vs_WT_F02.16903.16903.2 4.12E-06 20-Dec R.MGLIQTADQLR.F "sp|P18031|PTN1_HUMAN,tr|B4DSN5|B4DSN5_HUMAN" 2 1244.6547 46.7 16503 16903 2 1244.659402 623.3346 Tyrosine-protein phosphatase non-receptor type 1 OS=Homo sapiens OX=9606 GN=PTPN1 PE=1 SV=1 5.59 3138.7 - 1.53E+06 - - - 3.7721 - 2.596 0.524 - 541.6 1 2 0 0.0047 11 0 0 0 2.07E+07 4.44E+05 - - - 5.4905 0.9992 221125_WJC_METTL3_EV_vs_WT_F02.16906.16906.2 0.000813 22-Aug R.TVTPAMVEGIYK.Y sp|Q9P1Y5|CAMP3_HUMAN 1 1307.6795 2.57 16506 16906 2 1307.683129 654.847 Calmodulin-regulated spectrin-associated protein 3 OS=Homo sapiens OX=9606 GN=CAMSAP3 PE=1 SV=2 5.66 3139.1 - 598896 - - - 2.7568 - 1.786 0.46 - 139.3 1 2 0 0.0036 12 0 0 0 1.11E+07 4.33E+06 - - - 3.9635 0.9999 221125_WJC_METTL3_EV_vs_WT_F02.16911.16911.2 4.22E-06 20-Nov K.FVNWQVDGEYR[166.11].G "sp|O96008|TOM40_HUMAN,tr|K7EKG4|K7EKG4_HUMAN,tr|K7EJ57|K7EJ57_HUMAN" 3 1421.6603 1.21 16509 16911 2 1421.6593 711.8374 Mitochondrial import receptor subunit TOM40 homolog OS=Homo sapiens OX=9606 GN=TOMM40 PE=1 SV=1 4.37 3139.7 - 2.98E+06 - - - -0.7273 - 2.373 0.551 - 537.8 1 2 0 -0.001 11 0 0 0 4.24E+07 3.49E+07 - - - 5.4481 0.9997 221125_WJC_METTL3_EV_vs_WT_F02.16916.16916.2 0.00211 22-Oct R.IAVIADLDTESR.A "sp|Q8WVQ1|CANT1_HUMAN,tr|K7EN15|K7EN15_HUMAN" 2 1301.6827 2.32 16514 16916 2 1301.683054 651.8486 Soluble calcium-activated nucleotidase 1 OS=Homo sapiens OX=9606 GN=CANT1 PE=1 SV=1 4.03 3140.3 - 876847 - - - 0.275 - 2.235 0.343 - 230.5 1 2 0 0.0004 12 0 0 0 9.38E+06 4.05E+06 - - - 3.6904 0.999 221125_WJC_METTL3_EV_vs_WT_F02.16921.16921.2 0.0203 18-Nov K.GGVADALLYR.A "sp|P14406|CX7A2_HUMAN,tr|D6RIE3|D6RIE3_HUMAN,tr|H0UI06|H0UI06_HUMAN,tr|D6RGV5|D6RGV5_HUMAN,tr|D6R9C3|D6R9C3_HUMAN" 5 1033.5556 1.05 16517 16921 2 1033.55334 517.7851 "Cytochrome c oxidase subunit 7A2, mitochondrial OS=Homo sapiens OX=9606 GN=COX7A2 PE=1 SV=1" 5.84 3141 - 782976 - - - -2.2292 - 1.876 0.332 - 376.2 1 2 0 -0.0023 10 0 0 0 4.80E+07 4.55E+07 - - - 3.2486 1 221125_WJC_METTL3_EV_vs_WT_F02.16923.16923.2 1.14E-08 14/24 K.VAGMDVELTVEER[166.11].N "sp|P62258|1433E_HUMAN,tr|B4DJF2|B4DJF2_HUMAN,tr|I3L3T1|I3L3T1_HUMAN,tr|K7EIT4|K7EIT4_HUMAN" 4 1456.7107 1.26 16519 16923 2 1456.717703 729.3626 14-3-3 protein epsilon OS=Homo sapiens OX=9606 GN=YWHAE PE=1 SV=1 4 3141.2 - 2.24E+06 - - - 4.7971 - 2.996 0.562 - 885.9 1 2 0 0.007 13 0 0 0 2.25E+07 1.78E+07 - - - 6.0059 0.9999 221125_WJC_METTL3_EV_vs_WT_F02.16925.16925.3 0.000648 Dec-40 R.IYSHSLLPVLR.S sp|P22102|PUR2_HUMAN 1 1296.7554 0.76 16521 16925 3 1296.756158 433.2591 Trifunctional purine biosynthetic protein adenosine-3 OS=Homo sapiens OX=9606 GN=GART PE=1 SV=1 8.75 3141.4 - 1.10E+06 - - - 0.5791 - 2.51 0.423 - 240.6 1 2 0 0.0008 11 0 0 0 3.31E+07 4.36E+07 - - - 5.8702 0.9922 221125_WJC_METTL3_EV_vs_WT_F02.16926.16926.3 0.00906 Sep-32 K.YFIR[166.11]DEFLR[166.11].L "sp|P63092|GNAS2_HUMAN,sp|Q5JWF2|GNAS1_HUMAN,tr|A0A590UJ22|A0A590UJ22_HUMAN,tr|A0A590UJQ2|A0A590UJQ2_HUMAN,tr|A0A590UJR6|A0A590UJR6_HUMAN,tr|A0A590UK28|A0A590UK28_HUMAN,tr|A0A590UKB4|A0A590UKB4_HUMAN,tr|A0A590UJF0|A0A590UJF0_HUMAN,tr|Q5JWE9|Q5JWE9_HUMAN,tr|A0A590UJA5|A0A590UJA5_HUMAN,tr|A0A0A0MR13|A0A0A0MR13_HUMAN,tr|B0AZR9|B0AZR9_HUMAN,tr|A0A590UJI6|A0A590UJI6_HUMAN,tr|A0A590UJQ9|A0A590UJQ9_HUMAN,tr|A0A590UJ58|A0A590UJ58_HUMAN,tr|A0A590UJB7|A0A590UJB7_HUMAN,tr|A0A590UJJ0|A0A590UJJ0_HUMAN,tr|A0A7I2V5R6|A0A7I2V5R6_HUMAN,tr|A0A590UKA1|A0A590UKA1_HUMAN,tr|A0A804HIH4|A0A804HIH4_HUMAN,tr|A0A590UJY2|A0A590UJY2_HUMAN,tr|A0A590UJB0|A0A590UJB0_HUMAN,tr|A0A590UKA4|A0A590UKA4_HUMAN,tr|A0A590UJY8|A0A590UJY8_HUMAN,tr|A0A590UJG5|A0A590UJG5_HUMAN,tr|S4R3V9|S4R3V9_HUMAN,tr|A0A590UKA9|A0A590UKA9_HUMAN" 27 1277.6671 0.82 16522 16926 3 1277.667808 426.8963 Guanine nucleotide-binding protein G(s) subunit alpha isoforms short OS=Homo sapiens OX=9606 GN=GNAS PE=1 SV=1 6.07 3141.5 - 938775 - - - 0.5173 - 1.657 0.258 - 109.9 1 2 1 0.0007 9 0 0 0 1.02E+07 1.24E+07 - - - 2.9383 0.9999 221125_WJC_METTL3_EV_vs_WT_F02.16930.16930.2 2.88E-05 24-Dec R.WISSGEYIQMSGR[166.11].A sp|P42285|MTREX_HUMAN 1 1522.7114 0.64 16526 16930 2 1522.711481 762.363 Exosome RNA helicase MTR4 OS=Homo sapiens OX=9606 GN=MTREX PE=1 SV=3 6 3142 - 219812 - - - 0.0644 - 2.005 0.505 - 335.3 1 2 0 0.0001 13 0 0 0 5.58E+06 8.66E+06 - - - 4.5563 0.9997 221125_WJC_METTL3_EV_vs_WT_F02.16931.16931.2 5.42E-05 24-Sep R.WISSGEYIQMSGR.A sp|P42285|MTREX_HUMAN 1 1512.7031 0.64 16527 16931 2 1512.701156 757.3588 Exosome RNA helicase MTR4 OS=Homo sapiens OX=9606 GN=MTREX PE=1 SV=3 6 3142.1 - 204895 - - - -1.2937 - 1.804 0.484 - 169.5 1 2 0 -0.002 13 0 0 0 5.58E+06 8.66E+06 - - - 4.1295 0.9789 221125_WJC_METTL3_EV_vs_WT_F02.16934.16934.2 0.00534 16-Aug R.AVFPSIVGR[166.11].P "sp|Q6S8J3|POTEE_HUMAN,sp|P63261|ACTG_HUMAN,sp|P68133|ACTS_HUMAN,sp|P62736|ACTA_HUMAN,sp|P68032|ACTC_HUMAN,sp|P60709|ACTB_HUMAN,sp|P63267|ACTH_HUMAN,sp|A5A3E0|POTEF_HUMAN,sp|P0CG38|POTEI_HUMAN,tr|A0A804GS07|A0A804GS07_HUMAN,tr|I3L3I0|I3L3I0_HUMAN,tr|G5E9R0|G5E9R0_HUMAN,tr|E7EVS6|E7EVS6_HUMAN,tr|B8ZZJ2|B8ZZJ2_HUMAN,tr|J3KT65|J3KT65_HUMAN,tr|I3L3R2|I3L3R2_HUMAN,tr|K7EM38|K7EM38_HUMAN,tr|F6QUT6|F6QUT6_HUMAN,tr|C9JTX5|C9JTX5_HUMAN,tr|A0A6Q8PH58|A0A6Q8PH58_HUMAN,tr|F6UVQ4|F6UVQ4_HUMAN,tr|F8WB63|F8WB63_HUMAN,tr|I3L1U9|I3L1U9_HUMAN,tr|A0A2R8Y793|A0A2R8Y793_HUMAN,tr|I3L4N8|I3L4N8_HUMAN,tr|C9JUM1|C9JUM1_HUMAN,tr|F8WCH0|F8WCH0_HUMAN,tr|C9JZR7|C9JZR7_HUMAN,tr|C9JFL5|C9JFL5_HUMAN,tr|A0A2R8YGF8|A0A2R8YGF8_HUMAN,tr|A6NL76|A6NL76_HUMAN" 31 954.5526 1 16529 16934 2 954.552585 478.2836 POTE ankyrin domain family member E OS=Homo sapiens OX=9606 GN=POTEE PE=2 SV=3 9.79 3142.5 - 1.64E+07 - - - -0.0377 - 1.669 0.385 - 247.2 1 1 0 0 9 0 0 0 4.02E+08 4.02E+08 - - - 3.3665 0.9996 221125_WJC_METTL3_EV_vs_WT_F02.16935.16935.2 0.0147 18-Oct R.ENGVYLIDVK.F "sp|P21333|FLNA_HUMAN,tr|A0A7P0NMY4|A0A7P0NMY4_HUMAN,tr|Q60FE5|Q60FE5_HUMAN" 3 1148.6077 1.36 16530 16935 2 1148.608429 575.3111 Filamin-A OS=Homo sapiens OX=9606 GN=FLNA PE=1 SV=4 4.37 3142.5 - 2.52E+06 - - - 0.5999 - 1.922 0.343 - 525.1 1 2 0 0.0007 10 0 0 0 4.05E+07 2.98E+07 - - - 3.3979 0.9999 221125_WJC_METTL3_EV_vs_WT_F02.16939.16939.2 1.70E-06 16-Oct R.WDYLTQVEK[136.11].E sp|Q9HB71|CYBP_HUMAN 1 1188.5906 0.14 16534 16939 2 1188.591892 595.3026 Calcyclin-binding protein OS=Homo sapiens OX=9606 GN=CACYBP PE=1 SV=2 4.37 3142.7 - 5.40E+06 - - - 1.0533 - 2.093 0.529 - 377 1 2 0 0.0013 9 0 0 0 3.03E+07 2.13E+08 - - - 5.0846 0.9776 221125_WJC_METTL3_EV_vs_WT_F02.16940.16940.2 7.77E-06 18-Oct Y.LFNFASAATK[136.11].K sp|Q96A49|SYAP1_HUMAN 1 1076.5746 14.11 16535 16940 2 1076.577254 539.2946 Synapse-associated protein 1 OS=Homo sapiens OX=9606 GN=SYAP1 PE=1 SV=1 8.75 3142.7 - 2.27E+06 - - - 2.4699 - 2.098 0.508 - 286.9 1 1 0 0.0027 10 0 0 0 5.12E+08 3.63E+07 - - - 4.8606 0.9998 221125_WJC_METTL3_EV_vs_WT_F02.16941.16941.2 0.00824 16-Sep K.VQELQNLLK.G "sp|Q86UP2|KTN1_HUMAN,tr|G3V4Y7|G3V4Y7_HUMAN,tr|G3V5G2|G3V5G2_HUMAN" 3 1083.6288 1.79 16536 16941 2 1083.629069 542.8217 Kinectin OS=Homo sapiens OX=9606 GN=KTN1 PE=1 SV=1 5.97 3142.8 - 1.69E+06 - - - 0.2399 - 2.124 0.361 - 255.9 1 2 0 0.0003 9 0 0 0 1.76E+07 9.82E+06 - - - 3.8866 0.9996 221125_WJC_METTL3_EV_vs_WT_F02.16944.16944.2 0.00082 20-Nov R.IPVINLEDGTR.L sp|Q9P2D1|CHD7_HUMAN 1 1225.6667 1.37 16539 16944 2 1225.663732 613.8406 Chromodomain-helicase-DNA-binding protein 7 OS=Homo sapiens OX=9606 GN=CHD7 PE=1 SV=3 4.37 3143.1 - 724854 - - - -2.3824 - 2.247 0.463 - 482.1 1 2 0 -0.0029 11 0 0 0 1.74E+08 1.27E+08 - - - 4.6499 0.9999 221125_WJC_METTL3_EV_vs_WT_F02.16946.16946.2 4.73E-06 24-Dec K.VVPIASLTPYQSK.W sp|P27694|RFA1_HUMAN 1 1401.7868 1.22 16541 16946 2 1401.787436 701.9007 Replication protein A 70 kDa DNA-binding subunit OS=Homo sapiens OX=9606 GN=RPA1 PE=1 SV=2 8.56 3143.3 - 613263 - - - 0.4772 - 2.205 0.572 - 316.4 1 2 0 0.0007 13 0 0 0 3.69E+08 3.02E+08 - - - 5.295 0.9241 221125_WJC_METTL3_EV_vs_WT_F02.16950.16950.2 1.69 12-Jun K.DLNLLDR.C "sp|Q16850|CP51A_HUMAN,tr|H7C0D0|H7C0D0_HUMAN" 2 857.4607 3.81 16544 16950 2 857.46175 429.7376 Lanosterol 14-alpha demethylase OS=Homo sapiens OX=9606 GN=CYP51A1 PE=1 SV=4 4.21 3143.8 - 418441 - - - 1.2467 - 1.012 0.062 - 96.3 1 2 0 0.0011 7 0 0 0 5.98E+07 1.57E+07 - - - -0.4636 0.9999 221125_WJC_METTL3_EV_vs_WT_F02.16952.16952.2 8.09E-05 18-Oct K.TDLLLEPYNK.Y sp|P35579|MYH9_HUMAN 1 1204.634 0.95 16545 16952 2 1204.633967 603.3243 Myosin-9 OS=Homo sapiens OX=9606 GN=MYH9 PE=1 SV=4 4.37 3144 - 1.37E+07 - - - 0.0108 - 2.391 0.556 - 466.9 1 2 0 0 10 0 0 0 2.26E+08 2.37E+08 - - - 5.5808 0.9998 221125_WJC_METTL3_EV_vs_WT_F02.16953.16953.2 0.0407 18-Sep R.YGLSSMQGWR.V "sp|O75688|PPM1B_HUMAN,sp|P35813|PPM1A_HUMAN,tr|B8ZZF0|B8ZZF0_HUMAN,tr|A0A3B3IS24|A0A3B3IS24_HUMAN,tr|E9PL75|E9PL75_HUMAN,tr|C9JIR6|C9JIR6_HUMAN,tr|E9PKB5|E9PKB5_HUMAN,tr|E9PJN3|E9PJN3_HUMAN" 8 1183.5444 2.93 16546 16953 2 1183.545568 592.7795 Protein phosphatase 1B OS=Homo sapiens OX=9606 GN=PPM1B PE=1 SV=1 8.75 3144.1 - 1.53E+07 - - - 0.9632 - 1.962 0.436 - 232.8 1 2 0 0.0011 10 0 0 0 1.28E+09 4.36E+08 - - - 4.1422 0.9999 221125_WJC_METTL3_EV_vs_WT_F02.16954.16954.2 0.000353 20-Oct K.LVFLGEQSVGK.T "sp|P20340|RAB6A_HUMAN,sp|Q9NRW1|RAB6B_HUMAN,tr|F5H3K7|F5H3K7_HUMAN,tr|F5GX61|F5GX61_HUMAN,tr|C9J0I2|C9J0I2_HUMAN" 5 1175.655 1.95 16547 16954 2 1175.655114 588.8348 Ras-related protein Rab-6A OS=Homo sapiens OX=9606 GN=RAB6A PE=1 SV=3 6 3144.1 - 1.05E+07 - - - 0.0766 - 2.189 0.533 - 305 1 2 0 0.0001 11 0 0 0 3.01E+08 1.55E+08 - - - 5.0971 0.9996 221125_WJC_METTL3_EV_vs_WT_F02.16956.16956.2 8.67E-05 16-Oct K.AELNEFLTR[166.11].E "sp|P23396|RS3_HUMAN,tr|H0YEU2|H0YEU2_HUMAN,tr|E9PL09|E9PL09_HUMAN,tr|E9PK82|E9PK82_HUMAN,tr|H0YES8|H0YES8_HUMAN,tr|F2Z2S8|F2Z2S8_HUMAN,tr|H0YCJ7|H0YCJ7_HUMAN,tr|E9PQ96|E9PQ96_HUMAN,tr|E9PJH4|E9PJH4_HUMAN,tr|E9PQX2|E9PQX2_HUMAN,tr|E9PPU1|E9PPU1_HUMAN,tr|H0YF32|H0YF32_HUMAN" 12 1101.5694 0.69 16549 16956 2 1101.571975 551.792 40S ribosomal protein S3 OS=Homo sapiens OX=9606 GN=RPS3 PE=1 SV=2 4.53 3144.2 - 1.73E+06 - - - 2.343 - 1.962 0.491 - 424.5 1 2 0 0.0026 9 0 0 0 1.93E+09 2.79E+09 - - - 4.6165 0.9999 221125_WJC_METTL3_EV_vs_WT_F02.16957.16957.2 1.53E-06 24-Dec K.VVPIASLTPYQSK[136.11].W sp|P27694|RFA1_HUMAN 1 1409.801 1.22 16550 16957 2 1409.800865 705.9078 Replication protein A 70 kDa DNA-binding subunit OS=Homo sapiens OX=9606 GN=RPA1 PE=1 SV=2 8.56 3144.3 - 1.54E+06 - - - -0.0724 - 2.185 0.553 - 351.6 1 2 0 -0.0001 13 0 0 0 3.69E+08 3.02E+08 - - - 5.1315 0.9989 221125_WJC_METTL3_EV_vs_WT_F02.16958.16958.2 0.057 12-Aug R.C[160.03]ILPFDK[136.11].E "sp|Q9GZT3|SLIRP_HUMAN,tr|H0YJW7|H0YJW7_HUMAN,tr|A0A087WUN7|A0A087WUN7_HUMAN,tr|G3V2S9|G3V2S9_HUMAN,tr|H0YJ40|H0YJ40_HUMAN,tr|G3V4X6|G3V4X6_HUMAN" 6 899.4666 1.58 16551 16958 2 899.466371 450.7406 "SRA stem-loop-interacting RNA-binding protein, mitochondrial OS=Homo sapiens OX=9606 GN=SLIRP PE=1 SV=1" 5.83 3144.4 - 1.42E+06 - - - -0.2824 - 1.654 0.225 - 293.3 1 2 0 -0.0003 7 0 0 0 2.78E+08 1.76E+08 - - - 2.2972 1 221125_WJC_METTL3_EV_vs_WT_F02.16959.16959.2 2.39E-06 14/24 R.VVGAVIDQGLITR[166.11].H "sp|E9PRG8|CK098_HUMAN,tr|E9PLD3|E9PLD3_HUMAN,tr|A0A494BXY3|A0A494BXY3_HUMAN" 3 1349.7906 0.64 16552 16959 2 1349.789004 675.9026 Uncharacterized protein C11orf98 OS=Homo sapiens OX=9606 GN=C11orf98 PE=4 SV=2 5.81 3144.5 - 563191 - - - -1.1972 - 2.84 0.548 - 733.8 1 2 0 -0.0016 13 0 0 0 5.02E+07 7.85E+07 - - - 5.767 0.9997 221125_WJC_METTL3_EV_vs_WT_F02.16964.16964.2 0.0189 16-Sep K.AELNEFLTR.E "sp|P23396|RS3_HUMAN,tr|H0YEU2|H0YEU2_HUMAN,tr|E9PL09|E9PL09_HUMAN,tr|E9PK82|E9PK82_HUMAN,tr|H0YES8|H0YES8_HUMAN,tr|F2Z2S8|F2Z2S8_HUMAN,tr|H0YCJ7|H0YCJ7_HUMAN,tr|E9PQ96|E9PQ96_HUMAN,tr|E9PJH4|E9PJH4_HUMAN,tr|E9PQX2|E9PQX2_HUMAN,tr|E9PPU1|E9PPU1_HUMAN,tr|H0YF32|H0YF32_HUMAN" 12 1091.5611 0.69 16556 16964 2 1091.561128 546.7878 40S ribosomal protein S3 OS=Homo sapiens OX=9606 GN=RPS3 PE=1 SV=2 4.53 3145 - 2.49E+06 - - - 0.0037 - 1.977 0.357 - 445 1 2 0 0 9 0 0 0 1.94E+09 2.80E+09 - - - 3.6496 0.9994 221125_WJC_METTL3_EV_vs_WT_F02.16965.16965.2 0.116 16-Oct R.LYQVEYAFK[136.11].A "sp|P60900|PSA6_HUMAN,tr|G3V5Z7|G3V5Z7_HUMAN,tr|G3V295|G3V295_HUMAN,tr|G3V3I1|G3V3I1_HUMAN,tr|G3V3U4|G3V3U4_HUMAN" 5 1167.6056 0.81 16557 16965 2 1167.605827 584.8101 Proteasome subunit alpha type-6 OS=Homo sapiens OX=9606 GN=PSMA6 PE=1 SV=1 6 3145 - 2.13E+06 - - - 0.2278 - 1.831 0.289 - 262.3 1 2 0 0.0003 9 0 0 0 7.26E+07 8.98E+07 - - - 2.9254 0.9998 221125_WJC_METTL3_EV_vs_WT_F02.16967.16967.3 0.00294 Dec-48 K.VVPIASLTPYQSK.W sp|P27694|RFA1_HUMAN 1 1401.7868 1.23 16559 16967 3 1401.784919 468.2695 Replication protein A 70 kDa DNA-binding subunit OS=Homo sapiens OX=9606 GN=RPA1 PE=1 SV=2 8.56 3145.3 - 679963 - - - -1.3183 - 2.087 0.385 - 172.2 1 2 0 -0.0018 13 0 0 0 7.26E+07 5.89E+07 - - - 4.8266 0.9999 221125_WJC_METTL3_EV_vs_WT_F02.16968.16968.2 1.27E-05 20-Nov K.VWDYETGDFER.T "sp|P43034|LIS1_HUMAN,tr|A0A6Q8PH33|A0A6Q8PH33_HUMAN,tr|A0A6Q8PFU3|A0A6Q8PFU3_HUMAN,tr|A0A6Q8PG63|A0A6Q8PG63_HUMAN,tr|A0A6Q8PFT2|A0A6Q8PFT2_HUMAN" 5 1415.5994 1.63 16560 16968 2 1415.6012 708.807 Platelet-activating factor acetylhydrolase IB subunit beta OS=Homo sapiens OX=9606 GN=PAFAH1B1 PE=1 SV=2 3.92 3145.4 - 940989 - - - 1.2998 - 2.38 0.564 - 557.9 1 2 0 0.0018 11 0 0 0 5.29E+06 3.24E+06 - - - 5.5518 0.9998 221125_WJC_METTL3_EV_vs_WT_F02.16970.16970.2 2.34E-05 26-Sep R.YLGEVTGPATWSAR.E "sp|Q13487|SNPC2_HUMAN,tr|M0QXY9|M0QXY9_HUMAN" 2 1506.7467 0.45 16562 16970 2 1506.745258 754.3806 snRNA-activating protein complex subunit 2 OS=Homo sapiens OX=9606 GN=SNAPC2 PE=1 SV=1 6 3145.7 - 248184 - - - -0.9524 - 1.843 0.488 - 206.8 1 2 0 -0.0014 14 0 0 0 4.29E+06 9.52E+06 - - - 4.1792 1 221125_WJC_METTL3_EV_vs_WT_F02.16973.16973.2 3.97E-07 18-Nov R.YGLSSMQGWR[166.11].V "sp|O75688|PPM1B_HUMAN,sp|P35813|PPM1A_HUMAN,tr|B8ZZF0|B8ZZF0_HUMAN,tr|A0A3B3IS24|A0A3B3IS24_HUMAN,tr|E9PL75|E9PL75_HUMAN,tr|C9JIR6|C9JIR6_HUMAN,tr|E9PKB5|E9PKB5_HUMAN,tr|E9PJN3|E9PJN3_HUMAN" 8 1193.5527 2.93 16563 16973 2 1193.552406 597.7836 Protein phosphatase 1B OS=Homo sapiens OX=9606 GN=PPM1B PE=1 SV=1 8.75 3146.1 - 1.82E+07 - - - -0.2446 - 2.432 0.633 - 494.8 1 2 0 -0.0003 10 0 0 0 1.28E+09 4.36E+08 - - - 6.1969 1 221125_WJC_METTL3_EV_vs_WT_F02.16976.16976.2 6.47E-06 14/24 R.VVGAVIDQGLITR.H "sp|E9PRG8|CK098_HUMAN,tr|E9PLD3|E9PLD3_HUMAN,tr|A0A494BXY3|A0A494BXY3_HUMAN" 3 1339.7823 0.64 16566 16976 2 1339.78234 670.8985 Uncharacterized protein C11orf98 OS=Homo sapiens OX=9606 GN=C11orf98 PE=4 SV=2 5.81 3146.3 - 1.30E+06 - - - -0.0075 - 2.95 0.537 - 789.4 1 2 0 0 13 0 0 0 5.02E+07 7.85E+07 - - - 5.7838 0.9848 221125_WJC_METTL3_EV_vs_WT_F02.16979.16979.2 0.745 14-Aug K.TEIQTLFK.R "sp|Q8N6H7|ARFG2_HUMAN,tr|E9PM18|E9PM18_HUMAN,tr|E9PMU9|E9PMU9_HUMAN,tr|E9PNY8|E9PNY8_HUMAN,tr|H0YDX1|H0YDX1_HUMAN,tr|E9PIY6|E9PIY6_HUMAN,tr|E9PQP3|E9PQP3_HUMAN,tr|E9PJT7|E9PJT7_HUMAN,tr|E9PMR9|E9PMR9_HUMAN,tr|E9PN48|E9PN48_HUMAN,tr|E9PK28|E9PK28_HUMAN,tr|E9PM63|E9PM63_HUMAN,tr|G5E9L0|G5E9L0_HUMAN,tr|A0A0D9SF70|A0A0D9SF70_HUMAN" 14 978.5386 1.03 16569 16979 2 978.541179 490.2766 ADP-ribosylation factor GTPase-activating protein 2 OS=Homo sapiens OX=9606 GN=ARFGAP2 PE=1 SV=1 5.66 3146.7 - 441829 - - - 2.6386 - 1.369 0.165 - 145.7 1 2 0 0.0026 8 0 0 0 6.82E+06 6.62E+06 - - - 1.2061 0.9999 221125_WJC_METTL3_EV_vs_WT_F02.16982.16982.2 2.29E-06 28-Sep K.VEPYSLTAQQSSLIR.E "sp|Q96T88|UHRF1_HUMAN,tr|A0A087WWG9|A0A087WWG9_HUMAN,tr|A0A087WTW0|A0A087WTW0_HUMAN,tr|A0A087WVR3|A0A087WVR3_HUMAN" 4 1690.889 1.19 16572 16982 2 1690.889253 846.4518 E3 ubiquitin-protein ligase UHRF1 OS=Homo sapiens OX=9606 GN=UHRF1 PE=1 SV=1 5.97 3147.1 - 229532 - - - 0.1496 - 2.093 0.588 - 281 1 2 0 0.0003 15 0 0 0 2.88E+06 2.42E+06 - - - 5.1998 0.9997 221125_WJC_METTL3_EV_vs_WT_F02.16983.16983.2 8.51E-06 28-Oct K.VEPYSLTAQQSSLIR[166.11].E "sp|Q96T88|UHRF1_HUMAN,tr|A0A087WWG9|A0A087WWG9_HUMAN,tr|A0A087WTW0|A0A087WTW0_HUMAN,tr|A0A087WVR3|A0A087WVR3_HUMAN" 4 1700.8973 1.19 16573 16983 2 1700.894004 851.4559 E3 ubiquitin-protein ligase UHRF1 OS=Homo sapiens OX=9606 GN=UHRF1 PE=1 SV=1 5.97 3147.2 - 208280 - - - -1.9202 - 2.068 0.527 - 65.1 1 2 0 -0.0033 15 0 0 0 2.88E+06 2.42E+06 - - - 4.7187 0.9994 221125_WJC_METTL3_EV_vs_WT_F02.16987.16987.2 0.0915 14-Aug K.LIEIENFK.S "sp|Q14683|SMC1A_HUMAN,tr|V9GYN9|V9GYN9_HUMAN" 2 1004.5542 1.04 16575 16987 2 1004.55463 503.2844 Structural maintenance of chromosomes protein 1A OS=Homo sapiens OX=9606 GN=SMC1A PE=1 SV=2 4.53 3147.6 - 3.12E+06 - - - 0.3813 - 1.737 0.3 - 176.5 1 2 0 0.0004 8 0 0 0 1.67E+08 1.62E+08 - - - 2.922 0.999 221125_WJC_METTL3_EV_vs_WT_F02.16989.16989.3 0.0475 Oct-48 K.VVPIASLTPYQSK[136.11].W sp|P27694|RFA1_HUMAN 1 1409.801 1.23 16577 16989 3 1409.801549 470.9409 Replication protein A 70 kDa DNA-binding subunit OS=Homo sapiens OX=9606 GN=RPA1 PE=1 SV=2 8.56 3147.8 - 1.94E+06 - - - 0.4128 - 1.916 0.27 - 107.8 1 2 0 0.0006 13 0 0 0 7.26E+07 5.89E+07 - - - 3.3131 0.9986 221125_WJC_METTL3_EV_vs_WT_F02.16990.16990.2 0.00424 16-Sep R.AALQELLSK[136.11].G sp|P62851|RS25_HUMAN 1 979.5793 1.2 16578 16990 2 979.579217 490.7969 40S ribosomal protein S25 OS=Homo sapiens OX=9606 GN=RPS25 PE=1 SV=1 6.05 3147.9 - 1.43E+06 - - - -0.1327 - 1.869 0.164 - 201.9 1 2 0 -0.0001 9 0 0 0 1.02E+09 8.50E+08 - - - 2.0616 0.9999 221125_WJC_METTL3_EV_vs_WT_F02.16991.16991.2 4.03E-06 16-Sep R.VFDESLNFR[166.11].K "sp|Q5SW79|CE170_HUMAN,tr|E5RGW7|E5RGW7_HUMAN,tr|H0Y2V6|H0Y2V6_HUMAN,tr|E7EMW0|E7EMW0_HUMAN,tr|H0Y4T4|H0Y4T4_HUMAN,tr|E7EWM2|E7EWM2_HUMAN,tr|E5RG47|E5RG47_HUMAN" 7 1135.5537 1.16 16579 16991 2 1135.554114 568.7841 Centrosomal protein of 170 kDa OS=Homo sapiens OX=9606 GN=CEP170 PE=1 SV=1 4.37 3148 - 1.27E+06 - - - 0.3258 - 2.009 0.539 - 269.6 1 2 0 0.0004 9 0 0 0 5.58E+07 4.80E+07 - - - 5.0402 0.844 221125_WJC_METTL3_EV_vs_WT_F02.16992.16992.2 0.0503 14-Jul T.GFAYGFPK.A sp|O95907|MOT3_HUMAN 1 885.4385 0.26 16580 16992 2 885.438379 443.7265 Monocarboxylate transporter 3 OS=Homo sapiens OX=9606 GN=SLC16A8 PE=2 SV=1 8.59 3148.1 - 1.21E+06 - - - -0.1242 - 1.234 0.241 - 148 1 1 0 -0.0001 8 0 0 0 2.64E+07 1.00E+08 - - - 1.4551 0.9999 221125_WJC_METTL3_EV_vs_WT_F02.16993.16993.2 5.05E-07 14/22 R.FGLSAAEDITPR.F sp|Q9BUH6|PAXX_HUMAN 1 1275.6459 1.73 16581 16993 2 1275.646711 638.8302 Protein PAXX OS=Homo sapiens OX=9606 GN=PAXX PE=1 SV=2 4.37 3148.2 - 1.16E+06 - - - 0.6232 - 2.634 0.49 - 309.1 1 2 0 0.0008 12 0 0 0 3.51E+07 2.03E+07 - - - 5.2082 0.9914 221125_WJC_METTL3_EV_vs_WT_F02.16994.16994.2 0.0202 26-Aug R.LYPPDNAPLAFSSK[136.11].V "tr|A0A087WY03|A0A087WY03_HUMAN,tr|E5RFV3|E5RFV3_HUMAN" 2 1526.786 0.62 16582 16994 2 1526.779677 764.4003 Splicing regulatory glutamine\lysine-rich protein 1 OS=Homo sapiens OX=9606 GN=SREK1 PE=1 SV=1 5.83 3148.4 - 448524 - - - -4.1709 - 1.704 0.294 - 65 1 2 0 -0.0064 14 0 0 0 1.65E+07 2.65E+07 - - - 2.548 0.9998 221125_WJC_METTL3_EV_vs_WT_F02.16998.16998.2 0.000529 20-Dec K.QIAVEAQEILR.T "sp|Q14254|FLOT2_HUMAN,tr|E7EMK3|E7EMK3_HUMAN,tr|K7EKW9|K7EKW9_HUMAN,tr|J3QLD9|J3QLD9_HUMAN" 4 1268.7089 2.11 16584 16998 2 1268.70966 635.3617 Flotillin-2 OS=Homo sapiens OX=9606 GN=FLOT2 PE=1 SV=2 4.53 3148.9 - 1.62E+06 - - - 0.6377 - 2.095 0.413 - 672.5 1 2 0 0.0008 11 0 0 0 3.73E+07 1.77E+07 - - - 4.0918 0.9977 221125_WJC_METTL3_EV_vs_WT_F02.17002.17002.2 0.00775 12-Aug K.TYDYLFK.L "sp|P61006|RAB8A_HUMAN,sp|Q92930|RAB8B_HUMAN,tr|H0YMN7|H0YMN7_HUMAN,tr|H0YL94|H0YL94_HUMAN,tr|H0YNE9|H0YNE9_HUMAN,tr|H0YLJ8|H0YLJ8_HUMAN" 6 948.4593 0.94 16586 17002 2 948.459164 475.2369 Ras-related protein Rab-8A OS=Homo sapiens OX=9606 GN=RAB8A PE=1 SV=1 5.5 3149.4 - 2.00E+06 - - - -0.1265 - 1.207 0.274 - 262.4 1 2 0 -0.0001 7 0 0 0 3.54E+07 3.78E+07 - - - 1.6609 0.9999 221125_WJC_METTL3_EV_vs_WT_F02.17003.17003.3 1.27E-05 13/48 R.ILTDYGFEGHPFR.K sp|O75489|NDUS3_HUMAN 1 1550.7518 0.88 16587 17003 3 1550.752277 517.9245 "NADH dehydrogenase [ubiquinone] iron-sulfur protein 3, mitochondrial OS=Homo sapiens OX=9606 GN=NDUFS3 PE=1 SV=1" 5.32 3149.5 - 1.76E+06 - - - 0.3218 - 2.179 0.434 - 169.8 1 2 0 0.0005 13 0 0 0 3.63E+07 4.14E+07 - - - 5.4903 1 221125_WJC_METTL3_EV_vs_WT_F02.17007.17007.2 7.98E-10 22-Dec R.IMNTFSVVPSPK[136.11].V "sp|P04350|TBB4A_HUMAN,sp|P07437|TBB5_HUMAN,sp|Q13509|TBB3_HUMAN,sp|P68371|TBB4B_HUMAN,tr|M0R2D3|M0R2D3_HUMAN,tr|A0A0B4J269|A0A0B4J269_HUMAN,tr|Q5ST81|Q5ST81_HUMAN,tr|Q5JP53|Q5JP53_HUMAN,tr|M0R042|M0R042_HUMAN,tr|M0QYM7|M0QYM7_HUMAN,tr|G3V2A3|G3V2A3_HUMAN" 11 1326.7097 0.66 16589 17007 2 1326.710111 664.3621 Tubulin beta-4A chain OS=Homo sapiens OX=9606 GN=TUBB4A PE=1 SV=2 8.75 3150 - 2.40E+07 - - - 0.303 - 2.34 0.618 - 519.6 1 2 0 0.0004 12 0 0 0 4.50E+08 6.86E+08 - - - 5.8423 0.9982 221125_WJC_METTL3_EV_vs_WT_F02.17008.17008.2 0.0187 18-Jun R.ENFSVPVGLR[166.11].G "sp|Q8IZH2|XRN1_HUMAN,tr|H7C5E4|H7C5E4_HUMAN" 2 1126.601 1.12 16590 17008 2 1126.600907 564.3078 5'-3' exoribonuclease 1 OS=Homo sapiens OX=9606 GN=XRN1 PE=1 SV=1 6.1 3150 - 3.25E+06 - - - -0.1074 - 1.146 0.329 - 85.8 1 2 0 -0.0001 10 0 0 0 8.47E+07 7.55E+07 - - - 1.8513 0.9985 221125_WJC_METTL3_EV_vs_WT_F02.17010.17010.2 0.0834 16-Oct R.VFDESLNFR.K "sp|Q5SW79|CE170_HUMAN,tr|E5RGW7|E5RGW7_HUMAN,tr|H0Y2V6|H0Y2V6_HUMAN,tr|E7EMW0|E7EMW0_HUMAN,tr|H0Y4T4|H0Y4T4_HUMAN,tr|E7EWM2|E7EWM2_HUMAN,tr|E5RG47|E5RG47_HUMAN" 7 1125.5455 1.16 16592 17010 2 1125.546098 563.78 Centrosomal protein of 170 kDa OS=Homo sapiens OX=9606 GN=CEP170 PE=1 SV=1 4.37 3150.1 - 3.25E+06 - - - 0.5544 - 1.463 0.266 - 300.4 1 2 0 0.0006 9 0 0 0 5.58E+07 4.80E+07 - - - 2.1063 0.9995 221125_WJC_METTL3_EV_vs_WT_F02.17014.17014.2 0.000139 16-Oct R.LYQVEYAFK.A "sp|P60900|PSA6_HUMAN,tr|G3V5Z7|G3V5Z7_HUMAN,tr|G3V295|G3V295_HUMAN,tr|G3V3I1|G3V3I1_HUMAN,tr|G3V3U4|G3V3U4_HUMAN" 5 1159.5914 0.81 16594 17014 2 1159.59178 580.803 Proteasome subunit alpha type-6 OS=Homo sapiens OX=9606 GN=PSMA6 PE=1 SV=1 6 3150.6 - 2.82E+06 - - - 0.3613 - 1.972 0.276 - 251.6 1 2 0 0.0004 9 0 0 0 7.26E+07 8.98E+07 - - - 3.0439 0.9971 221125_WJC_METTL3_EV_vs_WT_F02.17016.17016.2 0.00391 14-Jun K.EGFTFEYR.Y "sp|O75175|CNOT3_HUMAN,tr|H7C5J4|H7C5J4_HUMAN,tr|A0A0G2JPP0|A0A0G2JPP0_HUMAN" 3 1047.4662 2.57 16596 17016 2 1047.469737 524.7404 CCR4-NOT transcription complex subunit 3 OS=Homo sapiens OX=9606 GN=CNOT3 PE=1 SV=1 4.53 3150.8 - 3.31E+06 - - - 3.414 - 1.414 0.407 - 139.3 1 2 0 0.0036 8 0 0 0 7.33E+07 2.86E+07 - - - 3.0908 0.9998 221125_WJC_METTL3_EV_vs_WT_F02.17017.17017.2 2.60E-05 14/22 K.LNDLEDALQQAK.E sp|P04264|K2C1_HUMAN 1 1356.6885 4.2 16597 17017 2 1356.687069 679.3515 "Keratin, type II cytoskeletal 1 OS=Homo sapiens OX=9606 GN=KRT1 PE=1 SV=6" 4.03 3150.9 - 953511 - - - -1.0614 - 2.889 0.373 - 882 1 2 0 -0.0014 12 0 0 0 4.17E+07 9.94E+06 - - - 4.587 0.9891 221125_WJC_METTL3_EV_vs_WT_F02.17018.17018.2 0.12 12-Jun K.DFLLTAR[166.11].R "sp|P63173|RL38_HUMAN,tr|J3KT73|J3KT73_HUMAN,tr|J3QL01|J3QL01_HUMAN,tr|J3KSP2|J3KSP2_HUMAN" 4 844.4682 1.04 16598 17018 2 844.466825 423.2414 60S ribosomal protein L38 OS=Homo sapiens OX=9606 GN=RPL38 PE=1 SV=2 5.84 3151.1 - 675985 - - - -1.6555 - 1.198 0.178 - 163 1 2 0 -0.0014 7 0 0 0 3.71E+07 3.57E+07 - - - 0.9277 0.9993 221125_WJC_METTL3_EV_vs_WT_F02.17019.17019.2 0.00569 20-Aug R.VYNYEPLTQLK.N "sp|Q9UJA3|MCM8_HUMAN,tr|A0A494C100|A0A494C100_HUMAN" 2 1366.7133 0.68 16599 17019 2 1366.715101 684.3639 DNA helicase MCM8 OS=Homo sapiens OX=9606 GN=MCM8 PE=1 SV=2 5.97 3151.2 - 444163 - - - 1.3419 - 1.718 0.356 - 144.7 1 2 0 0.0018 11 0 0 0 8.98E+06 1.32E+07 - - - 3.1338 0.9997 221125_WJC_METTL3_EV_vs_WT_F02.17022.17022.2 0.00441 18-Sep R.DVPLLPSDVK.L "sp|Q9HCE1|MOV10_HUMAN,tr|Q5JR04|Q5JR04_HUMAN" 2 1081.6019 1.4 16601 17022 2 1081.601983 541.8082 Helicase MOV-10 OS=Homo sapiens OX=9606 GN=MOV10 PE=1 SV=2 4.21 3151.5 - 1.21E+06 - - - 0.0527 - 1.737 0.395 - 269.4 1 2 0 0.0001 10 0 0 0 3.21E+07 2.30E+07 - - - 3.4997 0.9996 221125_WJC_METTL3_EV_vs_WT_F02.17024.17024.2 0.00297 14-Aug K.LIEIENFK[136.11].S "sp|Q14683|SMC1A_HUMAN,tr|V9GYN9|V9GYN9_HUMAN" 2 1012.5684 1.04 16602 17024 2 1012.568211 507.2915 Structural maintenance of chromosomes protein 1A OS=Homo sapiens OX=9606 GN=SMC1A PE=1 SV=2 4.53 3151.8 - 7.83E+06 - - - -0.2331 - 1.548 0.41 - 177.1 1 2 0 -0.0002 8 0 0 0 1.67E+08 1.60E+08 - - - 3.387 0.9977 221125_WJC_METTL3_EV_vs_WT_F02.17026.17026.2 0.222 12-Aug R.C[160.03]ILPFDK.E "sp|Q9GZT3|SLIRP_HUMAN,tr|H0YJW7|H0YJW7_HUMAN,tr|A0A087WUN7|A0A087WUN7_HUMAN,tr|G3V2S9|G3V2S9_HUMAN,tr|H0YJ40|H0YJ40_HUMAN,tr|G3V4X6|G3V4X6_HUMAN" 6 891.4524 1.58 16604 17026 2 891.451753 446.7335 "SRA stem-loop-interacting RNA-binding protein, mitochondrial OS=Homo sapiens OX=9606 GN=SLIRP PE=1 SV=1" 5.83 3151.9 - 8.91E+06 - - - -0.7538 - 1.666 0.148 - 292.1 1 2 0 -0.0007 7 0 0 0 2.78E+08 1.76E+08 - - - 1.7512 0.9994 221125_WJC_METTL3_EV_vs_WT_F02.17027.17027.2 0.00809 14-Aug R.WTLAVPGR[166.11].G "sp|Q9BYB4|GNB1L_HUMAN,tr|C9JPQ6|C9JPQ6_HUMAN" 2 908.5108 0.22 16605 17027 2 908.509966 455.2627 Guanine nucleotide-binding protein subunit beta-like protein 1 OS=Homo sapiens OX=9606 GN=GNB1L PE=1 SV=2 9.75 3152 - 1.36E+06 - - - -0.8707 - 1.755 0.308 - 326.7 1 2 0 -0.0008 8 0 0 0 6.99E+06 3.25E+07 - - - 3.012 0.9997 221125_WJC_METTL3_EV_vs_WT_F02.17029.17029.2 6.91E-07 24-Nov R.EMPGVWGAGGSLK[136.11].V "sp|Q9ULV3|CIZ1_HUMAN,tr|Q5SYW2|Q5SYW2_HUMAN,tr|F5H2X7|F5H2X7_HUMAN,tr|H0Y5D5|H0Y5D5_HUMAN,tr|A0A494C0L7|A0A494C0L7_HUMAN,tr|Q9BTG3|Q9BTG3_HUMAN" 6 1295.6424 2.47 16607 17029 2 1295.639732 648.8285 Cip1-interacting zinc finger protein OS=Homo sapiens OX=9606 GN=CIZ1 PE=1 SV=2 6.1 3152.2 - 646248 - - - -2.0268 - 2.018 0.485 - 368.2 1 2 0 -0.0026 13 0 0 0 7.13E+07 2.88E+07 - - - 4.4244 1 221125_WJC_METTL3_EV_vs_WT_F02.17031.17031.2 1.44E-09 15/28 R.AFVSMVYSEEGAEDR[166.11].T "sp|Q14683|SMC1A_HUMAN,tr|G8JLG1|G8JLG1_HUMAN,tr|A0A6Q8PHC3|A0A6Q8PHC3_HUMAN" 3 1698.7435 0.71 16609 17031 2 1698.742145 850.379 Structural maintenance of chromosomes protein 1A OS=Homo sapiens OX=9606 GN=SMC1A PE=1 SV=2 4 3152.5 - 575098 - - - -0.7806 - 3.173 0.735 - 719.8 1 2 0 -0.0013 15 0 0 0 9.13E+06 1.29E+07 - - - 7.3081 0.9938 221125_WJC_METTL3_EV_vs_WT_F02.17032.17032.2 0.00815 22-Oct R.EMAEAFAGEIPK[136.11].V "sp|O94973|AP2A2_HUMAN,tr|H0YDE9|H0YDE9_HUMAN,tr|A0A0G2JS82|A0A0G2JS82_HUMAN,tr|H0YEG0|H0YEG0_HUMAN,tr|E9PR62|E9PR62_HUMAN,tr|A0A0G2JQM1|A0A0G2JQM1_HUMAN,tr|E9PQP4|E9PQP4_HUMAN,tr|A0A0G2JS17|A0A0G2JS17_HUMAN,tr|A0A0G2JQT9|A0A0G2JQT9_HUMAN,tr|A0A0G2JQA4|A0A0G2JQA4_HUMAN,tr|A0A0G2JRF9|A0A0G2JRF9_HUMAN" 11 1299.626 0.001 16610 17032 2 1299.632939 650.8203 AP-2 complex subunit alpha-2 OS=Homo sapiens OX=9606 GN=AP2A2 PE=1 SV=2 4.25 3152.6 - 423352 - - - 5.3092 - 1.708 0.451 - 233.7 1 2 0 0.0069 12 0 0 0 0.00E+00 5.35E+06 - - - 3.7784 0.9996 221125_WJC_METTL3_EV_vs_WT_F02.17035.17035.2 3.54E-05 16-Nov K.TSFEIAELK[136.11].E "sp|O95619|YETS4_HUMAN,tr|F8W0J4|F8W0J4_HUMAN" 2 1044.5583 1.09 16611 17035 2 1044.556225 523.2864 YEATS domain-containing protein 4 OS=Homo sapiens OX=9606 GN=YEATS4 PE=1 SV=1 4.53 3153 - 3.81E+06 - - - -1.9645 - 1.807 0.449 - 340.5 1 2 0 -0.0021 9 0 0 0 6.62E+07 6.05E+07 - - - 4.0684 0.9998 221125_WJC_METTL3_EV_vs_WT_F02.17036.17036.2 2.89E-07 24-Nov R.EMPGVWGAGGSLK.V "sp|Q9ULV3|CIZ1_HUMAN,tr|Q5SYW2|Q5SYW2_HUMAN,tr|F5H2X7|F5H2X7_HUMAN,tr|H0Y5D5|H0Y5D5_HUMAN,tr|A0A494C0L7|A0A494C0L7_HUMAN,tr|Q9BTG3|Q9BTG3_HUMAN" 6 1287.6282 2.42 16612 17036 2 1287.626308 644.8214 Cip1-interacting zinc finger protein OS=Homo sapiens OX=9606 GN=CIZ1 PE=1 SV=2 6.1 3153.1 - 3.00E+06 - - - -1.4368 - 1.901 0.57 - 375.9 1 2 0 -0.0019 13 0 0 0 6.99E+07 2.88E+07 - - - 4.8991 0.9965 221125_WJC_METTL3_EV_vs_WT_F02.17037.17037.2 0.126 12-Jul K.DFLLTAR.R "sp|P63173|RL38_HUMAN,tr|J3KT73|J3KT73_HUMAN,tr|J3QL01|J3QL01_HUMAN,tr|J3KSP2|J3KSP2_HUMAN" 4 834.46 1.03 16613 17037 2 834.459208 418.2373 60S ribosomal protein L38 OS=Homo sapiens OX=9606 GN=RPL38 PE=1 SV=2 5.84 3153.2 - 1.87E+06 - - - -0.8928 - 1.379 0.191 - 245.4 1 2 0 -0.0007 7 0 0 0 3.71E+07 3.58E+07 - - - 1.4697 0.9998 221125_WJC_METTL3_EV_vs_WT_F02.17038.17038.2 0.000104 13/22 K.EVLLEAQDMAVR[166.11].D "sp|Q9NWU5|RM22_HUMAN,tr|E7ESL0|E7ESL0_HUMAN,tr|J3KQY1|J3KQY1_HUMAN" 3 1382.7103 1.15 16614 17038 2 1382.711173 692.3624 "39S ribosomal protein L22, mitochondrial OS=Homo sapiens OX=9606 GN=MRPL22 PE=1 SV=1" 4.14 3153.3 - 1.08E+06 - - - 0.6162 - 2.623 0.399 - 816.9 1 2 0 0.0009 12 0 0 0 2.79E+07 2.43E+07 - - - 4.525 0.9998 221125_WJC_METTL3_EV_vs_WT_F02.17041.17041.2 0.000284 13/22 K.VPIDGPPIDIGR.V sp|P11717|MPRI_HUMAN 1 1247.6874 1.55 16617 17041 2 1247.686215 624.851 Cation-independent mannose-6-phosphate receptor OS=Homo sapiens OX=9606 GN=IGF2R PE=1 SV=3 4.21 3153.7 - 680027 - - - -0.9393 - 2.271 0.457 - 647.5 1 2 0 -0.0012 12 0 0 0 2.06E+07 1.33E+07 - - - 4.5742 0.9999 221125_WJC_METTL3_EV_vs_WT_F02.17045.17045.2 0.121 20-Nov R.IPVINLEDGTR[166.11].L sp|Q9P2D1|CHD7_HUMAN 1 1235.6749 1.37 16620 17045 2 1235.674378 618.8447 Chromodomain-helicase-DNA-binding protein 7 OS=Homo sapiens OX=9606 GN=CHD7 PE=1 SV=3 4.37 3154.2 - 1.81E+06 - - - -0.4402 - 2.316 0.489 - 482.2 1 2 0 -0.0005 11 0 0 0 1.74E+08 1.27E+08 - - - 4.9246 0.9999 221125_WJC_METTL3_EV_vs_WT_F02.17047.17047.2 0.00128 13/22 K.EVLLEAQDMAVR.D "sp|Q9NWU5|RM22_HUMAN,tr|E7ESL0|E7ESL0_HUMAN,tr|J3KQY1|J3KQY1_HUMAN" 3 1372.7021 1.15 16621 17047 2 1372.701794 687.3583 "39S ribosomal protein L22, mitochondrial OS=Homo sapiens OX=9606 GN=MRPL22 PE=1 SV=1" 4.14 3154.4 - 1.83E+06 - - - -0.1872 - 2.604 0.462 - 827.2 1 2 0 -0.0003 12 0 0 0 2.79E+07 2.43E+07 - - - 4.9714 0.9971 221125_WJC_METTL3_EV_vs_WT_F02.17048.17048.2 0.0535 12-Jun R.EWEMQFK.E "sp|O15173|PGRC2_HUMAN,tr|U3KPU8|U3KPU8_HUMAN,tr|U3KQM0|U3KQM0_HUMAN" 3 996.4375 1.05 16622 17048 2 996.436642 499.226 Membrane-associated progesterone receptor component 2 OS=Homo sapiens OX=9606 GN=PGRMC2 PE=1 SV=1 4.53 3154.5 - 1.71E+06 - - - -0.8641 - 1.208 0.265 - 164.3 1 2 0 -0.0009 7 0 0 0 2.59E+07 2.48E+07 - - - 1.5968 0.9962 221125_WJC_METTL3_EV_vs_WT_F02.17049.17049.2 0.116 12-Jul K.DMLANFR.G sp|P15924|DESP_HUMAN 1 865.4116 21.98 16623 17049 2 865.411275 433.7131 Desmoplakin OS=Homo sapiens OX=9606 GN=DSP PE=1 SV=3 5.84 3154.6 - 1.66E+06 - - - -0.4021 - 1.419 0.156 - 268.1 1 2 0 -0.0003 7 0 0 0 4.30E+07 1.96E+06 - - - 1.302 0.9998 221125_WJC_METTL3_EV_vs_WT_F02.17050.17050.2 0.000109 16-Aug K.ENLVFLAQK[136.11].L "sp|P51692|STA5B_HUMAN,sp|P42229|STA5A_HUMAN,tr|A0A7I2YQY3|A0A7I2YQY3_HUMAN,tr|K7EIF9|K7EIF9_HUMAN,tr|K7EK35|K7EK35_HUMAN,tr|A0A7I2V380|A0A7I2V380_HUMAN,tr|A0A7I2YQF1|A0A7I2YQF1_HUMAN" 7 1068.6059 0.02 16624 17050 2 1068.605946 535.3102 Signal transducer and activator of transcription 5B OS=Homo sapiens OX=9606 GN=STAT5B PE=1 SV=2 6.1 3154.7 - 1.33E+06 - - - 0.0468 - 1.823 0.444 - 219.2 1 2 0 0.0001 9 0 0 0 4.40E+05 2.17E+07 - - - 4.0576 1 221125_WJC_METTL3_EV_vs_WT_F02.17051.17051.2 3.14E-10 16/28 R.AFVSMVYSEEGAEDR.T "sp|Q14683|SMC1A_HUMAN,tr|G8JLG1|G8JLG1_HUMAN,tr|A0A6Q8PHC3|A0A6Q8PHC3_HUMAN" 3 1688.7352 0.71 16625 17051 2 1688.735859 845.3749 Structural maintenance of chromosomes protein 1A OS=Homo sapiens OX=9606 GN=SMC1A PE=1 SV=2 4 3154.8 - 626251 - - - 0.3896 - 3.251 0.732 - 943.7 1 2 0 0.0007 15 0 0 0 9.13E+06 1.29E+07 - - - 7.3459 0.9999 221125_WJC_METTL3_EV_vs_WT_F02.17052.17052.2 1.48E-05 13/22 R.LLAEEEQQLLQR.L "sp|Q96F44|TRI11_HUMAN,tr|R4GMV1|R4GMV1_HUMAN" 2 1468.7886 44.87 16626 17052 2 1468.790326 735.4016 E3 ubiquitin-protein ligase TRIM11 OS=Homo sapiens OX=9606 GN=TRIM11 PE=1 SV=2 4.25 3154.9 - 622066 - - - 1.2037 - 2.839 0.508 - 640.3 1 2 0 0.0018 12 0 0 0 6.71E+06 1.50E+05 - - - 5.538 1 221125_WJC_METTL3_EV_vs_WT_F02.17056.17056.2 1.03E-06 14/22 R.IMNTFSVVPSPK.V "sp|P04350|TBB4A_HUMAN,sp|P07437|TBB5_HUMAN,sp|Q13509|TBB3_HUMAN,sp|P68371|TBB4B_HUMAN,tr|M0R2D3|M0R2D3_HUMAN,tr|A0A0B4J269|A0A0B4J269_HUMAN,tr|Q5ST81|Q5ST81_HUMAN,tr|Q5JP53|Q5JP53_HUMAN,tr|M0R042|M0R042_HUMAN,tr|M0QYM7|M0QYM7_HUMAN,tr|G3V2A3|G3V2A3_HUMAN" 11 1318.6955 0.66 16629 17056 2 1318.695052 660.355 Tubulin beta-4A chain OS=Homo sapiens OX=9606 GN=TUBB4A PE=1 SV=2 8.75 3155.4 - 8.16E+06 - - - -0.3466 - 2.57 0.615 - 755 1 2 0 -0.0005 12 0 0 0 4.50E+08 6.86E+08 - - - 6.0668 0.9999 221125_WJC_METTL3_EV_vs_WT_F02.17058.17058.2 0.00704 20-Nov K.SLVEIADTVPK.Y "sp|O00410|IPO5_HUMAN,sp|O60518|RNBP6_HUMAN,tr|H0Y8C6|H0Y8C6_HUMAN" 3 1170.6496 0.51 16630 17058 2 1170.649198 586.3321 Importin-5 OS=Homo sapiens OX=9606 GN=IPO5 PE=1 SV=4 4.37 3155.6 - 2.22E+06 - - - -0.3468 - 2.19 0.463 - 361.4 1 2 0 -0.0004 11 0 0 0 3.77E+07 7.42E+07 - - - 4.5812 0.9987 221125_WJC_METTL3_EV_vs_WT_F02.17059.17059.2 0.00319 16-Sep R.DSIVAELDR.E "sp|O14579|COPE_HUMAN,tr|M0QXB4|M0QXB4_HUMAN" 2 1016.5138 0.67 16631 17059 2 1016.515339 509.2642 Coatomer subunit epsilon OS=Homo sapiens OX=9606 GN=COPE PE=1 SV=3 4.03 3155.6 - 2.11E+06 - - - 1.4756 - 1.847 0.243 - 245.1 1 2 0 0.0015 9 0 0 0 2.84E+07 4.25E+07 - - - 2.6104 0.9999 221125_WJC_METTL3_EV_vs_WT_F02.17060.17060.2 0.000977 20-Dec K.SLVEIADTVPK[136.11].Y "sp|O00410|IPO5_HUMAN,sp|O60518|RNBP6_HUMAN,tr|H0Y8C6|H0Y8C6_HUMAN" 3 1178.6638 0.57 16632 17060 2 1178.663812 590.3392 Importin-5 OS=Homo sapiens OX=9606 GN=IPO5 PE=1 SV=4 4.37 3155.7 - 2.11E+06 - - - 0.0068 - 2.57 0.462 - 425.9 1 2 0 0 11 0 0 0 4.82E+07 8.52E+07 - - - 5.0068 0.9993 221125_WJC_METTL3_EV_vs_WT_F02.17061.17061.2 0.000404 18-Nov R.NLPVNFEVAR.E "sp|O95793|STAU1_HUMAN,tr|Q5JW30|Q5JW30_HUMAN" 2 1157.6193 1.98 16633 17061 2 1157.621589 579.8169 Double-stranded RNA-binding protein Staufen homolog 1 OS=Homo sapiens OX=9606 GN=STAU1 PE=1 SV=2 6 3155.8 - 1.43E+06 - - - 1.9713 - 1.891 0.366 - 393.6 1 2 0 0.0023 10 0 0 0 9.77E+07 4.94E+07 - - - 3.5219 0.9998 221125_WJC_METTL3_EV_vs_WT_F02.17063.17063.2 0.000168 18-Oct K.ANYAVDAYFR[166.11].E "sp|O60264|SMCA5_HUMAN,sp|P28370|SMCA1_HUMAN,tr|A0A0A0MRP6|A0A0A0MRP6_HUMAN,tr|B7ZLQ5|B7ZLQ5_HUMAN" 4 1198.5646 0.98 16635 17063 2 1198.564477 600.2896 SWI\SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A member 5 OS=Homo sapiens OX=9606 GN=SMARCA5 PE=1 SV=1 5.88 3155.9 - 1.24E+06 - - - -0.1385 - 2.192 0.427 - 428.8 1 2 0 -0.0002 10 0 0 0 1.00E+07 1.02E+07 - - - 4.3854 0.9999 221125_WJC_METTL3_EV_vs_WT_F02.17065.17065.3 2.22E-05 Dec-32 R.FVWNGHLLR.E "sp|Q9NTJ5|SAC1_HUMAN,tr|E9PGZ4|E9PGZ4_HUMAN,tr|A0A5F9ZHN7|A0A5F9ZHN7_HUMAN,tr|F8WDN7|F8WDN7_HUMAN" 4 1140.6192 0.98 16637 17065 3 1140.618904 381.2137 Phosphatidylinositol-3-phosphatase SAC1 OS=Homo sapiens OX=9606 GN=SACM1L PE=1 SV=2 9.76 3156.2 - 1.03E+06 - - - -0.3016 - 2.105 0.379 - 172.1 1 2 0 -0.0003 9 0 0 0 1.09E+07 1.11E+07 - - - 5.0086 0.9994 221125_WJC_METTL3_EV_vs_WT_F02.17066.17066.3 0.0181 Dec-32 R.FVWNGHLLR[166.11].E "sp|Q9NTJ5|SAC1_HUMAN,tr|E9PGZ4|E9PGZ4_HUMAN,tr|A0A5F9ZHN7|A0A5F9ZHN7_HUMAN,tr|F8WDN7|F8WDN7_HUMAN" 4 1150.6275 0.99 16638 17066 3 1150.627114 384.5498 Phosphatidylinositol-3-phosphatase SAC1 OS=Homo sapiens OX=9606 GN=SACM1L PE=1 SV=2 9.76 3156.3 - 1.01E+06 - - - -0.3511 - 1.655 0.32 - 158.1 1 2 0 -0.0004 9 0 0 0 1.10E+07 1.11E+07 - - - 3.6259 0.9999 221125_WJC_METTL3_EV_vs_WT_F02.17068.17068.2 0.000771 20-Dec R.AAAQYYLGNFR.S sp|O95801|TTC4_HUMAN 1 1272.6251 0.03 16640 17068 2 1272.625445 637.3198 Tetratricopeptide repeat protein 4 OS=Homo sapiens OX=9606 GN=TTC4 PE=1 SV=3 8.63 3156.6 - 875578 - - - 0.2546 - 2.672 0.515 - 690.7 1 2 0 0.0003 11 0 0 0 1.23E+07 4.54E+08 - - - 5.5035 0.9991 221125_WJC_METTL3_EV_vs_WT_F02.17073.17073.2 0.0146 16-Jun R.LIVNVNDLR[166.11].R sp|P25205|MCM3_HUMAN 1 1064.6218 0.48 16643 17073 2 1064.621597 533.3182 DNA replication licensing factor MCM3 OS=Homo sapiens OX=9606 GN=MCM3 PE=1 SV=3 5.84 3157.1 - 2.50E+06 - - - -0.1569 - 1.535 0.299 - 102.1 1 2 0 -0.0002 9 0 0 0 2.98E+07 6.25E+07 - - - 2.4891 0.9999 221125_WJC_METTL3_EV_vs_WT_F02.17074.17074.2 2.32E-06 22-Nov R.EMFGLYGQTTGK.G "sp|Q9Y6B6|SAR1B_HUMAN,tr|D6RD69|D6RD69_HUMAN,tr|D6R9R5|D6R9R5_HUMAN,tr|Q9H029|Q9H029_HUMAN" 4 1330.6227 1.06 16644 17074 2 1330.622943 666.3186 GTP-binding protein SAR1b OS=Homo sapiens OX=9606 GN=SAR1B PE=1 SV=1 6.1 3157.2 - 2.14E+06 - - - 0.1541 - 1.717 0.576 - 373.4 1 2 0 0.0002 12 0 0 0 2.40E+07 2.26E+07 - - - 4.7176 0.9805 221125_WJC_METTL3_EV_vs_WT_F02.17075.17075.2 0.000706 20-Sep K.GQVFALSTHPY.G "sp|Q14671|PUM1_HUMAN,tr|Q5T1Z8|Q5T1Z8_HUMAN,tr|H0YDK8|H0YDK8_HUMAN,tr|H0YEH2|H0YEH2_HUMAN,tr|Q5T1Z4|Q5T1Z4_HUMAN,tr|E9PR38|E9PR38_HUMAN,tr|H0YDQ6|H0YDQ6_HUMAN" 7 1218.6033 - 16645 17075 2 1218.602393 610.3089 Pumilio homolog 1 OS=Homo sapiens OX=9606 GN=PUM1 PE=1 SV=3 6.74 3157.3 - 1.79E+06 - - - -0.7632 - 1.94 0.37 - 226.9 1 1 0 -0.0009 11 0 0 0 - - - - - 3.5663 0.9912 221125_WJC_METTL3_EV_vs_WT_F02.17076.17076.2 0.000552 18-Sep R.AAEPLLTLER[166.11].L "sp|O60524|NEMF_HUMAN,tr|G3V5V3|G3V5V3_HUMAN,tr|G3V4D9|G3V4D9_HUMAN" 3 1121.632 0.86 16646 17076 2 1121.634671 561.8233 Nuclear export mediator factor NEMF OS=Homo sapiens OX=9606 GN=NEMF PE=1 SV=4 4.53 3157.3 - 1.70E+06 - - - 2.3867 - 1.764 0.117 - 298.3 1 2 0 0.0027 10 0 0 0 2.75E+07 3.20E+07 - - - 1.4886 0.9017 221125_WJC_METTL3_EV_vs_WT_F02.17086.17086.2 0.106 18-Aug R.VNTHGIFTIS.T "sp|Q92598|HS105_HUMAN,tr|A0A0A0MSM0|A0A0A0MSM0_HUMAN" 2 1087.5662 - 16655 17086 2 1087.566076 544.7904 Heat shock protein 105 kDa OS=Homo sapiens OX=9606 GN=HSPH1 PE=1 SV=1 6.71 3158.4 - 3.60E+06 - - - -0.1223 - 1.516 0.225 - 109.1 1 1 0 -0.0001 10 0 0 0 - - - - - 1.8642 0.9997 221125_WJC_METTL3_EV_vs_WT_F02.17087.17087.2 0.000811 16-Sep R.TALFEEISR[166.11].S "sp|Q14683|SMC1A_HUMAN,tr|G8JLG1|G8JLG1_HUMAN" 2 1074.5585 1.04 16656 17087 2 1074.559233 538.2865 Structural maintenance of chromosomes protein 1A OS=Homo sapiens OX=9606 GN=SMC1A PE=1 SV=2 4.53 3158.5 - 3.49E+06 - - - 0.6868 - 1.939 0.373 - 420.5 1 2 0 0.0007 9 0 0 0 7.66E+07 7.37E+07 - - - 3.7114 0.9934 221125_WJC_METTL3_EV_vs_WT_F02.17089.17089.2 0.000416 16-Jul K.LITWSPVC[160.03]R.N "sp|P07203|GPX1_HUMAN,tr|A0A2R8Y6B6|A0A2R8Y6B6_HUMAN" 2 1130.5907 1.54 16658 17089 2 1130.595176 566.3026 Glutathione peroxidase 1 OS=Homo sapiens OX=9606 GN=GPX1 PE=1 SV=4 8.25 3158.6 - 1.32E+06 - - - 4.0032 - 1.695 0.289 - 162.6 1 2 0 0.0045 9 0 0 0 1.10E+07 7.16E+06 - - - 2.7007 0.9727 221125_WJC_METTL3_EV_vs_WT_F02.17090.17090.2 1.46 12-May R.EWEMQFK[136.11].E "sp|O15173|PGRC2_HUMAN,tr|U3KPU8|U3KPU8_HUMAN,tr|U3KQM0|U3KQM0_HUMAN" 3 1004.4517 1.04 16659 17090 2 1004.452106 503.2331 Membrane-associated progesterone receptor component 2 OS=Homo sapiens OX=9606 GN=PGRMC2 PE=1 SV=1 4.53 3158.7 - 1.31E+06 - - - 0.4012 - 0.922 0.164 - 85 1 2 0 0.0004 7 0 0 0 2.61E+07 2.51E+07 - - - -0.0051 0.9997 221125_WJC_METTL3_EV_vs_WT_F02.17092.17092.2 1.00E-05 20-Oct R.FFTSSTSLTLK.H "sp|Q99567|NUP88_HUMAN,tr|J3KMX1|J3KMX1_HUMAN,tr|I3L245|I3L245_HUMAN" 3 1230.6496 6.63 16661 17092 2 1230.652046 616.3321 Nuclear pore complex protein Nup88 OS=Homo sapiens OX=9606 GN=NUP88 PE=1 SV=2 8.75 3158.8 - 1.13E+06 - - - 1.9843 - 1.813 0.565 - 158.5 1 2 0 0.0024 11 0 0 0 4.10E+08 6.18E+07 - - - 4.8229 0.9958 221125_WJC_METTL3_EV_vs_WT_F02.17093.17093.2 0.000449 20-Oct R.VLQPGTALFSR[166.11].R sp|P47224|MSS4_HUMAN 1 1197.6745 1.06 16662 17093 2 1197.67999 599.8445 Guanine nucleotide exchange factor MSS4 OS=Homo sapiens OX=9606 GN=RABIF PE=1 SV=2 9.72 3158.9 - 815828 - - - 4.5605 - 1.959 0.373 - 245.7 1 2 0 0.0055 11 0 0 0 6.60E+06 6.25E+06 - - - 3.6134 0.8525 221125_WJC_METTL3_EV_vs_WT_F02.17094.17094.2 1.04 14-Jun K.GLDSFLNR[166.11].D sp|Q96QC0|PP1RA_HUMAN 1 930.4799 0.42 16663 17094 2 930.476943 466.2472 Serine\threonine-protein phosphatase 1 regulatory subunit 10 OS=Homo sapiens OX=9606 GN=PPP1R10 PE=1 SV=1 5.84 3159 - 799878 - - - -3.1242 - 1.183 0.036 - 88.7 1 2 0 -0.0029 8 0 0 0 2.74E+06 6.58E+06 - - - -0.1872 0.9449 221125_WJC_METTL3_EV_vs_WT_F02.17095.17095.2 0.068 20-Aug R.IYVGNLPPDIR[166.11].T "sp|Q07955|SRSF1_HUMAN,tr|J3QQV5|J3QQV5_HUMAN,tr|J3KTL2|J3KTL2_HUMAN,tr|J3KSW7|J3KSW7_HUMAN" 4 1265.7007 2.14 16664 17095 2 1265.707931 633.8576 Serine\arginine-rich splicing factor 1 OS=Homo sapiens OX=9606 GN=SRSF1 PE=1 SV=2 5.84 3159.1 - 629617 - - - 5.6799 - 1.477 0.239 - 194.9 1 2 0 0.0072 11 0 0 0 1.47E+07 6.85E+06 - - - 1.8591 0.9996 221125_WJC_METTL3_EV_vs_WT_F02.17096.17096.2 0.00114 20-Oct K.MYDDAIEAIEK[136.11].H "sp|O60476|MA1A2_HUMAN,tr|H0Y7H1|H0Y7H1_HUMAN" 2 1304.605 0.95 16665 17096 2 1304.604789 653.3098 "Mannosyl-oligosaccharide 1,2-alpha-mannosidase IB OS=Homo sapiens OX=9606 GN=MAN1A2 PE=1 SV=1" 3.92 3159.3 - 594101 - - - -0.138 - 1.506 0.423 - 208.7 1 2 0 -0.0002 11 0 0 0 4.17E+06 4.38E+06 - - - 3.2729 0.9999 221125_WJC_METTL3_EV_vs_WT_F02.17098.17098.2 5.23E-08 24-Oct R.LLPLTQYPDSSVR[166.11].R sp|Q9BTY7|HGH1_HUMAN 1 1497.8067 0.41 16667 17098 2 1497.807907 749.9106 Protein HGH1 homolog OS=Homo sapiens OX=9606 GN=HGH1 PE=1 SV=1 5.84 3159.5 - 405448 - - - 0.8299 - 2.01 0.591 - 345.3 1 2 0 0.0012 13 0 0 0 2.05E+06 4.98E+06 - - - 5.1975 1 221125_WJC_METTL3_EV_vs_WT_F02.17099.17099.2 9.96E-09 30-Oct M.VLESTMVC[160.03]VDNSEYMR.N "sp|P55036|PSMD4_HUMAN,tr|Q5VWC4|Q5VWC4_HUMAN" 2 1931.8427 1.33 16668 17099 2 1931.840389 966.9286 26S proteasome non-ATPase regulatory subunit 4 OS=Homo sapiens OX=9606 GN=PSMD4 PE=1 SV=1 4.14 3159.6 - 292758 - - - -1.2066 - 2.003 0.689 - 170.4 1 2 0 -0.0023 16 0 0 0 2.93E+06 2.20E+06 - - - 5.837 0.9999 221125_WJC_METTL3_EV_vs_WT_F02.17105.17105.2 9.10E-07 14/22 R.VAMFLTDSNNIK[136.11].E sp|Q15046|SYK_HUMAN 1 1359.6948 0.42 16672 17105 2 1359.693895 680.8547 Lysine--tRNA ligase OS=Homo sapiens OX=9606 GN=KARS1 PE=1 SV=3 5.81 3160.4 - 1.36E+06 - - - -0.656 - 2.255 0.5 - 784.4 1 2 0 -0.0009 12 0 0 0 2.63E+07 6.19E+07 - - - 4.8733 0.9991 221125_WJC_METTL3_EV_vs_WT_F02.17107.17107.2 0.00237 16-Sep R.TALFEEISR.S "sp|Q14683|SMC1A_HUMAN,tr|G8JLG1|G8JLG1_HUMAN" 2 1064.5502 1.04 16674 17107 2 1064.551602 533.2824 Structural maintenance of chromosomes protein 1A OS=Homo sapiens OX=9606 GN=SMC1A PE=1 SV=2 4.53 3160.5 - 5.52E+06 - - - 1.2935 - 1.718 0.304 - 295.4 1 2 0 0.0014 9 0 0 0 7.87E+07 7.56E+07 - - - 2.8515 0.9996 221125_WJC_METTL3_EV_vs_WT_F02.17113.17113.2 0.00134 18-Dec R.LASGDWFTSR[166.11].T sp|P30154|2AAB_HUMAN 1 1148.549 8.57 16680 17113 2 1148.54874 575.2818 Serine\threonine-protein phosphatase 2A 65 kDa regulatory subunit A beta isoform OS=Homo sapiens OX=9606 GN=PPP2R1B PE=1 SV=3 5.84 3161.1 - 622962 - - - -0.2203 - 1.538 0.391 - 437.2 1 2 0 -0.0003 10 0 0 0 4.24E+07 4.94E+06 - - - 3.1305 0.8716 221125_WJC_METTL3_EV_vs_WT_F02.17114.17114.2 1.34 14-Jun A.IAIGDLVK.S "sp|P78371|TCPB_HUMAN,tr|F8VQ14|F8VQ14_HUMAN,tr|F5GWF6|F5GWF6_HUMAN" 3 827.5117 0.53 16681 17114 2 827.511474 414.7631 T-complex protein 1 subunit beta OS=Homo sapiens OX=9606 GN=CCT2 PE=1 SV=4 5.84 3161.2 - 313684 - - - -0.2175 - 1.283 0.267 - 68.1 2 1 0 -0.0002 8 0 0 0 1.37E+07 2.59E+07 - - - 1.6301 0.8372 221125_WJC_METTL3_EV_vs_WT_F02.17121.17121.2 0.228 14-Aug A.IAIGDLVK[136.11].S "sp|P78371|TCPB_HUMAN,tr|F8VQ14|F8VQ14_HUMAN,tr|F5GWF6|F5GWF6_HUMAN" 3 835.5259 0.53 16686 17121 2 835.525476 418.7702 T-complex protein 1 subunit beta OS=Homo sapiens OX=9606 GN=CCT2 PE=1 SV=4 5.84 3162.1 - 1.72E+06 - - - -0.4524 - 1.485 0.163 - 141.5 1 1 0 -0.0004 8 0 0 0 1.37E+07 2.60E+07 - - - 1.4374 0.9998 221125_WJC_METTL3_EV_vs_WT_F02.17127.17127.2 2.88E-06 22-Nov R.VAMFLTDSNNIK.E sp|Q15046|SYK_HUMAN 1 1351.6806 0.42 16692 17127 2 1351.681742 676.8476 Lysine--tRNA ligase OS=Homo sapiens OX=9606 GN=KARS1 PE=1 SV=3 5.81 3162.6 - 1.04E+06 - - - 0.8545 - 2.504 0.404 - 486.3 1 2 0 0.0012 12 0 0 0 2.50E+07 5.92E+07 - - - 4.4397 0.9999 221125_WJC_METTL3_EV_vs_WT_F02.17128.17128.2 2.14E-07 13/24 K.ELGSLTTANLMEK.V "sp|Q52LA3|LIN52_HUMAN,tr|B3KN83|B3KN83_HUMAN" 2 1405.7123 2.07 16693 17128 2 1405.711472 703.8634 Protein lin-52 homolog OS=Homo sapiens OX=9606 GN=LIN52 PE=1 SV=1 4.53 3162.7 - 876111 - - - -0.5755 - 2.403 0.548 - 465.3 1 2 0 -0.0008 13 0 0 0 6.88E+06 3.32E+06 - - - 5.3384 1 221125_WJC_METTL3_EV_vs_WT_F02.17129.17129.2 0.000754 14/26 R.VLNSYWVGEDSTYK[136.11].F "sp|P61313|RL15_HUMAN,tr|A0A2R8YEM3|A0A2R8YEM3_HUMAN,tr|A0A2R8Y738|A0A2R8Y738_HUMAN,tr|E7EQV9|E7EQV9_HUMAN,tr|E7EX53|E7EX53_HUMAN,tr|E7ENU7|E7ENU7_HUMAN" 6 1667.7923 1.04 16694 17129 2 1667.794117 834.9034 60S ribosomal protein L15 OS=Homo sapiens OX=9606 GN=RPL15 PE=1 SV=2 4.37 3162.8 - 742898 - - - 1.1176 - 2.862 0.61 - 613.2 1 2 0 0.0019 14 0 0 0 3.21E+07 3.07E+07 - - - 6.1846 0.9999 221125_WJC_METTL3_EV_vs_WT_F02.17130.17130.2 6.86E-06 26-Dec R.VLNSYWVGEDSTYK.F "sp|P61313|RL15_HUMAN,tr|A0A2R8YEM3|A0A2R8YEM3_HUMAN,tr|A0A2R8Y738|A0A2R8Y738_HUMAN,tr|E7EQV9|E7EQV9_HUMAN,tr|E7EX53|E7EX53_HUMAN,tr|E7ENU7|E7ENU7_HUMAN" 6 1659.7781 1.04 16695 17130 2 1659.775918 830.8963 60S ribosomal protein L15 OS=Homo sapiens OX=9606 GN=RPL15 PE=1 SV=2 4.37 3162.9 - 507739 - - - -1.2863 - 2.655 0.553 - 515.6 1 2 0 -0.0021 14 0 0 0 3.21E+07 3.07E+07 - - - 5.5751 0.9954 221125_WJC_METTL3_EV_vs_WT_F02.17131.17131.2 0.0994 14-Jul R.WEQVPLIK.E sp|P23919|KTHY_HUMAN 1 1011.5753 1.43 16696 17131 2 1011.57475 506.7949 Thymidylate kinase OS=Homo sapiens OX=9606 GN=DTYMK PE=1 SV=4 6 3163.1 - 475341 - - - -0.5605 - 1.211 0.212 - 86.2 1 2 0 -0.0006 8 0 0 0 2.95E+06 2.07E+06 - - - 1.184 0.995 221125_WJC_METTL3_EV_vs_WT_F02.17132.17132.2 0.0119 12-Jul K.AFLFVNK[136.11].G sp|Q8N0X7|SPART_HUMAN 1 845.4891 0.88 16697 17132 2 845.491063 423.7518 Spartin OS=Homo sapiens OX=9606 GN=SPART PE=1 SV=1 8.8 3163.2 - 438820 - - - 2.3513 - 1.459 0.228 - 161.5 1 2 0 0.002 7 0 0 0 2.03E+06 2.31E+06 - - - 1.9213 0.885 221125_WJC_METTL3_EV_vs_WT_F02.17135.17135.2 0.133 12-Jul R.K[136.11]IELFGR[166.11].P sp|Q86U44|MTA70_HUMAN 1 879.5297 0.001 16700 17135 2 879.527928 440.7721 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 8.75 3163.6 - 391960 - - - -2.0238 - 1.692 0.227 - 246.8 1 1 0 -0.0018 7 0 0 0 0.00E+00 5.44E+06 - - - 2.3834 0.9984 221125_WJC_METTL3_EV_vs_WT_F02.17136.17136.2 0.0094 14-Jul K.FVADGIFK.A "sp|P23396|RS3_HUMAN,tr|H0YEU2|H0YEU2_HUMAN,tr|E9PL09|E9PL09_HUMAN,tr|E9PK82|E9PK82_HUMAN,tr|H0YES8|H0YES8_HUMAN,tr|F2Z2S8|F2Z2S8_HUMAN,tr|H0YCJ7|H0YCJ7_HUMAN,tr|E9PQ96|E9PQ96_HUMAN,tr|E9PJH4|E9PJH4_HUMAN,tr|E9PQX2|E9PQX2_HUMAN,tr|E9PPU1|E9PPU1_HUMAN" 11 895.4804 0.66 16701 17136 2 895.478595 448.7475 40S ribosomal protein S3 OS=Homo sapiens OX=9606 GN=RPS3 PE=1 SV=2 5.84 3163.7 - 262012 - - - -1.9643 - 1.324 0.372 - 121.5 1 2 0 -0.0018 8 0 0 0 6.79E+07 1.03E+08 - - - 2.6345 0.9999 221125_WJC_METTL3_EV_vs_WT_F02.17142.17142.2 0.00944 18-Nov K.LNC[160.03]FLEQDLK.L "sp|P52732|KIF11_HUMAN,tr|A0A7I2V3A9|A0A7I2V3A9_HUMAN" 2 1278.6278 4.35 16706 17142 2 1278.627299 640.3212 Kinesin-like protein KIF11 OS=Homo sapiens OX=9606 GN=KIF11 PE=1 SV=2 4.37 3164.3 - 9.41E+06 - - - -0.4098 - 2.534 0.538 - 848.4 1 2 0 -0.0005 10 0 0 0 1.40E+09 3.21E+08 - - - 5.6099 1 221125_WJC_METTL3_EV_vs_WT_F02.17143.17143.3 0.00163 14/40 K.WEGLVYAPPGK.E "sp|Q9Y2W1|TR150_HUMAN,tr|A0A3B3ITZ9|A0A3B3ITZ9_HUMAN" 2 1215.6288 2.87 16707 17143 3 1215.627539 406.2169 Thyroid hormone receptor-associated protein 3 OS=Homo sapiens OX=9606 GN=THRAP3 PE=1 SV=2 6 3164.4 - 3.69E+06 - - - -1.0447 - 2.669 0.443 - 245.2 1 2 0 -0.0013 11 0 0 0 3.04E+08 1.06E+08 - - - 6.2675 0.9995 221125_WJC_METTL3_EV_vs_WT_F02.17144.17144.2 5.43E-05 13/20 R.VIGTLLGTVDK[136.11].H "sp|O00303|EIF3F_HUMAN,tr|A0A1W2PP79|A0A1W2PP79_HUMAN,tr|H0YDT6|H0YDT6_HUMAN,tr|A0A7I2YQA0|A0A7I2YQA0_HUMAN" 4 1122.674 1.06 16708 17144 2 1122.676962 562.3443 Eukaryotic translation initiation factor 3 subunit F OS=Homo sapiens OX=9606 GN=EIF3F PE=1 SV=1 5.81 3164.4 - 2.97E+06 - - - 2.6606 - 2.433 0.442 - 439.3 1 2 0 0.003 11 0 0 0 6.58E+07 6.21E+07 - - - 4.71 0.9999 221125_WJC_METTL3_EV_vs_WT_F02.17145.17145.2 0.000215 18-Nov K.LNC[160.03]FLEQDLK[136.11].L "sp|P52732|KIF11_HUMAN,tr|A0A7I2V3A9|A0A7I2V3A9_HUMAN" 2 1286.642 4.34 16709 17145 2 1286.639916 644.3283 Kinesin-like protein KIF11 OS=Homo sapiens OX=9606 GN=KIF11 PE=1 SV=2 4.37 3164.5 - 2.50E+06 - - - -1.6376 - 2.588 0.539 - 736.6 1 2 0 -0.0021 10 0 0 0 1.40E+09 3.23E+08 - - - 5.6756 0.9997 221125_WJC_METTL3_EV_vs_WT_F02.17146.17146.2 0.00114 20-Sep R.VIGTLLGTVDK.H "sp|O00303|EIF3F_HUMAN,tr|A0A1W2PP79|A0A1W2PP79_HUMAN,tr|H0YDT6|H0YDT6_HUMAN,tr|A0A7I2YQA0|A0A7I2YQA0_HUMAN" 4 1114.6598 1.06 16710 17146 2 1114.661875 558.3372 Eukaryotic translation initiation factor 3 subunit F OS=Homo sapiens OX=9606 GN=EIF3F PE=1 SV=1 5.81 3164.5 - 2.25E+06 - - - 1.884 - 2.127 0.471 - 157.7 1 2 0 0.0021 11 0 0 0 6.58E+07 6.21E+07 - - - 4.5608 0.9999 221125_WJC_METTL3_EV_vs_WT_F02.17147.17147.3 0.00344 Dec-40 K.WEGLVYAPPGK[136.11].E "sp|Q9Y2W1|TR150_HUMAN,tr|A0A3B3ITZ9|A0A3B3ITZ9_HUMAN" 2 1223.643 2.87 16711 17147 3 1223.641466 408.8883 Thyroid hormone receptor-associated protein 3 OS=Homo sapiens OX=9606 GN=THRAP3 PE=1 SV=2 6 3164.6 - 1.78E+06 - - - -1.261 - 2.641 0.374 - 207.7 1 2 0 -0.0015 11 0 0 0 3.04E+08 1.06E+08 - - - 5.4682 0.9999 221125_WJC_METTL3_EV_vs_WT_F02.17150.17150.2 3.76E-07 14/22 K.WMEEQAQSLIDK.T "sp|P09234|RU1C_HUMAN,tr|A0A0A0MRR7|A0A0A0MRR7_HUMAN" 2 1476.6919 1.63 16714 17150 2 1476.691769 739.3532 U1 small nuclear ribonucleoprotein C OS=Homo sapiens OX=9606 GN=SNRPC PE=1 SV=1 4.14 3164.9 - 869968 - - - -0.0752 - 2.278 0.559 - 688.8 1 2 0 -0.0001 12 0 0 0 6.94E+07 4.26E+07 - - - 5.336 0.9986 221125_WJC_METTL3_EV_vs_WT_F02.17151.17151.2 0.964 18-Sep R.SLVGGLLQSK.F "sp|P52948|NUP98_HUMAN,tr|A0A3B3ITD8|A0A3B3ITD8_HUMAN,tr|H7C3P6|H7C3P6_HUMAN" 3 1000.5917 1.5 16715 17151 2 1000.592222 501.3031 Nuclear pore complex protein Nup98-Nup96 OS=Homo sapiens OX=9606 GN=NUP98 PE=1 SV=4 8.47 3165 - 755061 - - - 0.5257 - 1.634 0.233 - 207 1 2 0 0.0005 10 0 0 0 1.25E+08 8.33E+07 - - - 2.1324 0.999 221125_WJC_METTL3_EV_vs_WT_F02.17152.17152.2 0.0985 18-Oct R.SLVGGLLQSK[136.11].F "sp|P52948|NUP98_HUMAN,tr|A0A3B3ITD8|A0A3B3ITD8_HUMAN,tr|H7C3P6|H7C3P6_HUMAN" 3 1008.6059 1.49 16716 17152 2 1008.607145 505.3102 Nuclear pore complex protein Nup98-Nup96 OS=Homo sapiens OX=9606 GN=NUP98 PE=1 SV=4 8.47 3165.2 - 703530 - - - 1.2383 - 1.739 0.294 - 266.9 1 2 0 0.0012 10 0 0 0 1.25E+08 8.33E+07 - - - 2.7565 0.9998 221125_WJC_METTL3_EV_vs_WT_F02.17153.17153.2 0.0024 16-Oct R.LFEGNALLR.R "sp|P46781|RS9_HUMAN,tr|C9JM19|C9JM19_HUMAN,tr|B5MCT8|B5MCT8_HUMAN" 3 1031.5764 2.16 16717 17153 2 1031.576279 516.7955 40S ribosomal protein S9 OS=Homo sapiens OX=9606 GN=RPS9 PE=1 SV=3 6 3165.3 - 591398 - - - -0.0979 - 1.906 0.416 - 322.9 1 2 0 -0.0001 9 0 0 0 9.36E+06 4.34E+06 - - - 3.9796 1 221125_WJC_METTL3_EV_vs_WT_F02.17154.17154.2 1.81E-12 17/30 K.APGAIGPYSQAVLVDR.T sp|P52758|RIDA_HUMAN 1 1612.8573 2.44 16718 17154 2 1612.860606 807.4359 2-iminobutanoate\2-iminopropanoate deaminase OS=Homo sapiens OX=9606 GN=RIDA PE=1 SV=1 5.88 3165.4 - 474396 - - - 2.0461 - 3.158 0.649 - 890.8 1 2 0 0.0033 16 0 0 0 3.45E+06 1.41E+06 - - - 6.6607 1 221125_WJC_METTL3_EV_vs_WT_F02.17155.17155.2 2.59E-06 30-Nov K.APGAIGPYSQAVLVDR[166.11].T sp|P52758|RIDA_HUMAN 1 1622.8656 1.83 16719 17155 2 1622.865174 812.4401 2-iminobutanoate\2-iminopropanoate deaminase OS=Homo sapiens OX=9606 GN=RIDA PE=1 SV=1 5.88 3165.6 - 247244 - - - -0.2477 - 2.696 0.592 - 275.3 1 2 0 -0.0004 16 0 0 0 3.93E+06 2.14E+06 - - - 5.8517 0.9998 221125_WJC_METTL3_EV_vs_WT_F02.17161.17161.2 0.000156 22-Sep K.AYIQENLELVEK.G "sp|P11586|C1TC_HUMAN,tr|F5H2F4|F5H2F4_HUMAN,tr|V9GZ78|V9GZ78_HUMAN,tr|V9GYY3|V9GYY3_HUMAN,tr|A0A494C1T2|A0A494C1T2_HUMAN" 5 1447.7559 2.06 16724 17161 2 1447.754372 724.8852 "C-1-tetrahydrofolate synthase, cytoplasmic OS=Homo sapiens OX=9606 GN=MTHFD1 PE=1 SV=4" 4.25 3166.1 - 2.62E+06 - - - -1.0285 - 2.087 0.446 - 239.4 1 2 0 -0.0015 12 0 0 0 6.17E+07 2.99E+07 - - - 4.2705 0.9994 221125_WJC_METTL3_EV_vs_WT_F02.17163.17163.2 0.000153 18-Oct K.FLQFVTGTSK[136.11].V "sp|Q7Z6Z7|HUWE1_HUMAN,tr|H0Y659|H0Y659_HUMAN" 2 1134.6165 1.89 16726 17163 2 1134.613117 568.3155 E3 ubiquitin-protein ligase HUWE1 OS=Homo sapiens OX=9606 GN=HUWE1 PE=1 SV=3 8.75 3166.2 - 1.93E+06 - - - -2.9464 - 1.944 0.509 - 324.3 1 2 0 -0.0033 10 0 0 0 4.02E+07 2.13E+07 - - - 4.6549 0.9965 221125_WJC_METTL3_EV_vs_WT_F02.17164.17164.2 5.55E-06 18-Nov R.TVFC[160.03]MQLAAR.L "sp|Q14498|RBM39_HUMAN,sp|Q86U06|RBM23_HUMAN,tr|Q5QP22|Q5QP22_HUMAN,tr|H0Y4X3|H0Y4X3_HUMAN,tr|A0A0U1RQH7|A0A0U1RQH7_HUMAN,tr|Q5QP23|Q5QP23_HUMAN,tr|G3XAC6|G3XAC6_HUMAN" 7 1195.5842 0.99 16727 17164 2 1195.590486 598.7994 RNA-binding protein 39 OS=Homo sapiens OX=9606 GN=RBM39 PE=1 SV=2 7.91 3166.2 - 1.74E+06 - - - 5.2711 - 1.866 0.51 - 426.9 1 2 0 0.0063 10 0 0 0 9.95E+06 1.00E+07 - - - 4.5471 0.9011 221125_WJC_METTL3_EV_vs_WT_F02.17165.17165.2 0.000941 18-Aug R.TVFC[160.03]MQLAAR[166.11].L "sp|Q14498|RBM39_HUMAN,sp|Q86U06|RBM23_HUMAN,tr|Q5QP22|Q5QP22_HUMAN,tr|H0Y4X3|H0Y4X3_HUMAN,tr|A0A0U1RQH7|A0A0U1RQH7_HUMAN,tr|Q5QP23|Q5QP23_HUMAN,tr|G3XAC6|G3XAC6_HUMAN" 7 1205.5925 1.08 16728 17165 2 1205.601674 603.8035 RNA-binding protein 39 OS=Homo sapiens OX=9606 GN=RBM39 PE=1 SV=2 7.91 3166.3 - 1.65E+06 - - - 7.6477 - 1.448 0.293 - 198.1 1 2 0 0.0092 10 0 0 0 1.09E+07 1.01E+07 - - - 2.2355 0.9932 221125_WJC_METTL3_EV_vs_WT_F02.17167.17167.2 0.0281 16-Jul R.FFMGNQVLK[136.11].V sp|P13010|XRCC5_HUMAN 1 1090.5725 0.68 16730 17167 2 1090.575469 546.2935 X-ray repair cross-complementing protein 5 OS=Homo sapiens OX=9606 GN=XRCC5 PE=1 SV=3 8.75 3166.4 - 1.37E+06 - - - 2.7343 - 1.295 0.283 - 96.9 1 2 0 0.003 9 0 0 0 1.12E+07 1.63E+07 - - - 1.8782 0.9596 221125_WJC_METTL3_EV_vs_WT_F02.17168.17168.2 0.00283 15/24 L.TLGIETVGGVMTK[136.11].L "sp|P11021|BIP_HUMAN,tr|A0A7P0TB36|A0A7P0TB36_HUMAN,tr|A0A7P0TAI0|A0A7P0TAI0_HUMAN" 3 1312.7152 0.67 16731 17168 2 1312.710775 657.3649 Endoplasmic reticulum chaperone BiP OS=Homo sapiens OX=9606 GN=HSPA5 PE=1 SV=2 5.66 3166.5 - 1.18E+06 - - - -3.3617 - 2.61 0.456 - 616.4 1 1 0 -0.0044 13 0 0 0 9.09E+06 1.36E+07 - - - 4.8698 0.9999 221125_WJC_METTL3_EV_vs_WT_F02.17169.17169.2 3.26E-07 16-Sep R.YEDMAAFMK.G sp|P31947|1433S_HUMAN 1 1104.462 64.5 16732 17169 2 1104.462001 553.2383 14-3-3 protein sigma OS=Homo sapiens OX=9606 GN=SFN PE=1 SV=1 4.37 3166.7 - 1.07E+06 - - - -0.0018 - 1.816 0.642 - 189.8 1 2 0 0 9 0 0 0 1.87E+07 2.90E+05 - - - 5.5089 1 221125_WJC_METTL3_EV_vs_WT_F02.17170.17170.2 0.00173 16/26 R.LQEAGILSAEELQR.L "sp|Q15149|PLEC_HUMAN,tr|H0YDN1|H0YDN1_HUMAN" 2 1555.8206 1.52 16733 17170 2 1555.825112 778.9176 Plectin OS=Homo sapiens OX=9606 GN=PLEC PE=1 SV=3 4.25 3166.8 - 882352 - - - 2.9091 - 3.198 0.553 - 1059.4 1 2 0 0.0045 14 0 0 0 1.73E+07 1.14E+07 - - - 6.0413 1 221125_WJC_METTL3_EV_vs_WT_F02.17171.17171.2 3.41E-07 15/26 R.LQEAGILSAEELQR[166.11].L "sp|Q15149|PLEC_HUMAN,tr|H0YDN1|H0YDN1_HUMAN" 2 1565.8289 1.65 16734 17171 2 1565.826873 783.9217 Plectin OS=Homo sapiens OX=9606 GN=PLEC PE=1 SV=3 4.25 3166.9 - 617546 - - - -1.2664 - 3.14 0.561 - 955.7 1 2 0 -0.002 14 0 0 0 1.93E+07 1.17E+07 - - - 6.0553 0.9906 221125_WJC_METTL3_EV_vs_WT_F02.17172.17172.2 0.062 18-Aug K.EAQEEIAFLK[136.11].L "sp|Q14789|GOGB1_HUMAN,tr|E7EU81|E7EU81_HUMAN,tr|H0Y867|H0Y867_HUMAN" 3 1184.6169 0.74 16735 17172 2 1184.613878 593.3157 Golgin subfamily B member 1 OS=Homo sapiens OX=9606 GN=GOLGB1 PE=1 SV=2 4.25 3167.1 - 522722 - - - -2.5122 - 1.347 0.217 - 108 1 2 0 -0.003 10 0 0 0 3.21E+06 4.35E+06 - - - 1.4743 0.9997 221125_WJC_METTL3_EV_vs_WT_F02.17175.17175.2 7.85E-06 22-Sep R.GFLSGPMGSGMR[166.11].E "sp|Q9P2K5|MYEF2_HUMAN,tr|A0A0A0MR39|A0A0A0MR39_HUMAN,tr|A0A0C4DGV1|A0A0C4DGV1_HUMAN,tr|A0A087WUT0|A0A087WUT0_HUMAN,tr|H0YKS1|H0YKS1_HUMAN,tr|H0YN19|H0YN19_HUMAN,tr|A0A0A0MQW0|A0A0A0MQW0_HUMAN" 7 1205.5561 1.01 16736 17175 2 1205.553097 603.7853 Myelin expression factor 2 OS=Homo sapiens OX=9606 GN=MYEF2 PE=1 SV=3 9.75 3167.4 - 2.19E+06 - - - -2.4653 - 1.903 0.576 - 223.8 1 2 0 -0.003 12 0 0 0 8.33E+07 8.22E+07 - - - 4.9874 0.9998 221125_WJC_METTL3_EV_vs_WT_F02.17176.17176.2 1.05E-06 20-Dec R.ELAVQIYEEAR[166.11].K "sp|O00571|DDX3X_HUMAN,sp|O15523|DDX3Y_HUMAN,tr|A0A2R8YFR4|A0A2R8YFR4_HUMAN,tr|A0A2R8YCW1|A0A2R8YCW1_HUMAN,tr|A0A2R8YDH3|A0A2R8YDH3_HUMAN,tr|A0A2R8YDT5|A0A2R8YDT5_HUMAN,tr|A0A2R8Y645|A0A2R8Y645_HUMAN,tr|A0A2R8YF78|A0A2R8YF78_HUMAN,tr|A0A0D9SFB3|A0A0D9SFB3_HUMAN,tr|A0A2R8YFS5|A0A2R8YFS5_HUMAN,tr|A0A0D9SF53|A0A0D9SF53_HUMAN,tr|A0A2R8Y5G6|A0A2R8Y5G6_HUMAN,tr|A0A2R8Y7T2|A0A2R8Y7T2_HUMAN,tr|A0A0D9SG12|A0A0D9SG12_HUMAN,tr|A0A2U3TZJ9|A0A2U3TZJ9_HUMAN,tr|A0A2R8Y4A4|A0A2R8Y4A4_HUMAN" 16 1329.6804 1.27 16737 17176 2 1329.682664 665.8475 ATP-dependent RNA helicase DDX3X OS=Homo sapiens OX=9606 GN=DDX3X PE=1 SV=3 4.25 3167.6 - 1.26E+06 - - - 1.7019 - 2.644 0.496 - 767.8 1 2 0 0.0023 11 0 0 0 2.75E+08 2.17E+08 - - - 5.334 0.9997 221125_WJC_METTL3_EV_vs_WT_F02.17177.17177.2 0.159 20-Sep R.YEILTPNAIPK.G "sp|Q7Z406|MYH14_HUMAN,sp|P35580|MYH10_HUMAN,tr|M0QY43|M0QY43_HUMAN" 3 1257.6969 1.16 16738 17177 2 1257.69563 629.8557 Myosin-14 OS=Homo sapiens OX=9606 GN=MYH14 PE=1 SV=2 6 3167.6 - 2.59E+06 - - - -1.001 - 1.74 0.419 - 254.5 1 2 0 -0.0013 11 0 0 0 6.66E+07 5.75E+07 - - - 3.6337 0.9724 221125_WJC_METTL3_EV_vs_WT_F02.17179.17179.2 0.102 18-Oct A.LAIVEALNGK.E "sp|Q99497|PARK7_HUMAN,tr|K7EN27|K7EN27_HUMAN,tr|K7ELW0|K7ELW0_HUMAN" 3 1026.6073 2.83 16740 17179 2 1026.6072 514.3109 Parkinson disease protein 7 OS=Homo sapiens OX=9606 GN=PARK7 PE=1 SV=2 6 3167.8 - 945555 - - - -0.1422 - 2.065 0.272 - 235.1 1 1 0 -0.0001 10 0 0 0 7.56E+07 2.67E+07 - - - 3.074 1 221125_WJC_METTL3_EV_vs_WT_F02.17180.17180.3 9.79E-05 17/48 R.FAVLLTDKPTIPR.E "sp|Q5VWN6|TASO2_HUMAN,tr|A0A2R8YH03|A0A2R8YH03_HUMAN" 2 1469.8606 1.95 16741 17180 3 1469.86212 490.9608 Protein TASOR 2 OS=Homo sapiens OX=9606 GN=TASOR2 PE=1 SV=1 8.75 3168 - 790990 - - - 1.0341 - 2.919 0.439 - 294.3 1 2 0 0.0015 13 0 0 0 8.35E+06 4.29E+06 - - - 6.3384 0.9999 221125_WJC_METTL3_EV_vs_WT_F02.17183.17183.2 1.02E-05 20-Dec K.WEGLVYAPPGK.E "sp|Q9Y2W1|TR150_HUMAN,tr|A0A3B3ITZ9|A0A3B3ITZ9_HUMAN" 2 1215.6288 2.79 16743 17183 2 1215.629391 608.8217 Thyroid hormone receptor-associated protein 3 OS=Homo sapiens OX=9606 GN=THRAP3 PE=1 SV=2 6 3168.3 - 5.58E+08 - - - 0.4788 - 2.008 0.577 - 364.4 1 2 0 0.0006 11 0 0 0 1.48E+10 5.30E+09 - - - 5.1885 0.9998 221125_WJC_METTL3_EV_vs_WT_F02.17187.17187.2 0.000119 13/20 R.NELESYAYSLK[136.11].N "sp|P11021|BIP_HUMAN,tr|A0A7P0TB36|A0A7P0TB36_HUMAN,tr|A0A7P0TAI0|A0A7P0TAI0_HUMAN" 3 1323.6438 0.55 16746 17187 2 1323.645994 662.8292 Endoplasmic reticulum chaperone BiP OS=Homo sapiens OX=9606 GN=HSPA5 PE=1 SV=2 4.53 3168.8 - 1.88E+06 - - - 1.6598 - 2.536 0.522 - 744.7 1 2 0 0.0022 11 0 0 0 2.53E+08 4.57E+08 - - - 5.4133 0.9969 221125_WJC_METTL3_EV_vs_WT_F02.17188.17188.2 0.0123 16-Aug R.FFMGNQVLK.V sp|P13010|XRCC5_HUMAN 1 1082.5583 0.68 16747 17188 2 1082.556527 542.2864 X-ray repair cross-complementing protein 5 OS=Homo sapiens OX=9606 GN=XRCC5 PE=1 SV=3 8.75 3168.9 - 1.13E+06 - - - -1.6258 - 1.251 0.294 - 109.8 1 2 0 -0.0018 9 0 0 0 1.12E+07 1.63E+07 - - - 1.8598 0.9996 221125_WJC_METTL3_EV_vs_WT_F02.17189.17189.2 0.000547 18-Oct K.TAFGIISTVK[136.11].K "sp|P78346|RPP30_HUMAN,tr|Q5VU10|Q5VU10_HUMAN" 2 1043.6106 0.71 16748 17189 2 1043.60996 522.8126 Ribonuclease P protein subunit p30 OS=Homo sapiens OX=9606 GN=RPP30 PE=1 SV=1 8.41 3169 - 1.02E+06 - - - -0.6583 - 1.833 0.347 - 261.5 1 2 0 -0.0007 10 0 0 0 2.23E+07 3.15E+07 - - - 3.2951 0.9991 221125_WJC_METTL3_EV_vs_WT_F02.17190.17190.3 0.000646 15/44 K.LIVAYVDDLDR[166.11]R[166.11].G "sp|O14776|TCRG1_HUMAN,tr|A0A7P0T8N8|A0A7P0T8N8_HUMAN" 2 1466.7996 0.63 16749 17190 3 1466.792938 489.9405 Transcription elongation regulator 1 OS=Homo sapiens OX=9606 GN=TCERG1 PE=1 SV=2 4.43 3169.2 - 806936 - - - -4.5541 - 2.553 0.384 - 359.1 1 2 0 -0.0067 12 0 0 0 1.85E+07 2.94E+07 - - - 5.4173 0.9945 221125_WJC_METTL3_EV_vs_WT_F02.17196.17196.2 1.13 14-Aug K.NLYIISVK[136.11].G "sp|P62829|RL23_HUMAN,tr|J3KT29|J3KT29_HUMAN,tr|B9ZVP7|B9ZVP7_HUMAN,tr|C9JD32|C9JD32_HUMAN" 4 956.5786 1 16753 17196 2 956.577247 479.2966 60S ribosomal protein L23 OS=Homo sapiens OX=9606 GN=RPL23 PE=1 SV=1 8.59 3170 - 4.38E+06 - - - -1.4332 - 1.493 0.146 - 270.8 1 2 0 -0.0014 8 0 0 0 1.09E+09 1.09E+09 - - - 1.3277 0.9997 221125_WJC_METTL3_EV_vs_WT_F02.17197.17197.2 9.14E-06 13/22 R.IDVVVNNAGILR[166.11].D "sp|P51659|DHB4_HUMAN,tr|A0A804HK88|A0A804HK88_HUMAN,tr|A0A2R8YD50|A0A2R8YD50_HUMAN,tr|E7ER27|E7ER27_HUMAN,tr|A0A2R8YF45|A0A2R8YF45_HUMAN,tr|E7EPL9|E7EPL9_HUMAN,tr|A0A804HKU2|A0A804HKU2_HUMAN,tr|A0A2R8YDT8|A0A2R8YDT8_HUMAN,tr|A0A804HK65|A0A804HK65_HUMAN" 9 1291.7488 0.64 16754 17197 2 1291.745843 646.8817 Peroxisomal multifunctional enzyme type 2 OS=Homo sapiens OX=9606 GN=HSD17B4 PE=1 SV=3 5.84 3170.1 - 2.01E+06 - - - -2.2543 - 2.642 0.482 - 725.9 1 2 0 -0.0029 12 0 0 0 3.70E+07 5.81E+07 - - - 5.1564 0.9989 221125_WJC_METTL3_EV_vs_WT_F02.17198.17198.2 0.00694 18-Oct K.TAFGIISTVK.K "sp|P78346|RPP30_HUMAN,tr|Q5VU10|Q5VU10_HUMAN" 2 1035.5964 0.71 16755 17198 2 1035.595141 518.8055 Ribonuclease P protein subunit p30 OS=Homo sapiens OX=9606 GN=RPP30 PE=1 SV=1 8.41 3170.2 - 1.03E+06 - - - -1.2611 - 1.617 0.29 - 221.5 1 2 0 -0.0013 10 0 0 0 2.22E+07 3.11E+07 - - - 2.524 0.9962 221125_WJC_METTL3_EV_vs_WT_F02.17199.17199.2 0.00199 16-Sep R.MQLSEIMER[166.11].D sp|P78316|NOP14_HUMAN 1 1145.5448 0.57 16756 17199 2 1145.539722 573.7797 Nucleolar protein 14 OS=Homo sapiens OX=9606 GN=NOP14 PE=1 SV=3 4.53 3170.3 - 962696 - - - -4.4634 - 1.864 0.373 - 293.5 1 2 0 -0.0051 9 0 0 0 7.92E+06 1.39E+07 - - - 3.5959 0.9996 221125_WJC_METTL3_EV_vs_WT_F02.17205.17205.2 0.000432 15/26 K.SLVSTPAGPVNVLK.G sp|Q96T58|MINT_HUMAN 1 1380.7977 1.52 16760 17205 2 1380.794272 691.4061 Msx2-interacting protein OS=Homo sapiens OX=9606 GN=SPEN PE=1 SV=1 8.47 3171.1 - 1.67E+06 - - - -2.458 - 2.346 0.462 - 570.5 1 2 0 -0.0034 14 0 0 0 1.03E+08 6.75E+07 - - - 4.5921 0.9998 221125_WJC_METTL3_EV_vs_WT_F02.17206.17206.2 4.15E-06 13/26 K.SLVSTPAGPVNVLK[136.11].G sp|Q96T58|MINT_HUMAN 1 1388.8119 1.52 16761 17206 2 1388.810445 695.4132 Msx2-interacting protein OS=Homo sapiens OX=9606 GN=SPEN PE=1 SV=1 8.47 3171.2 - 1.29E+06 - - - -1.0232 - 2.5 0.461 - 427.6 1 2 0 -0.0014 14 0 0 0 1.03E+08 6.76E+07 - - - 4.7449 0.9998 221125_WJC_METTL3_EV_vs_WT_F02.17213.17213.2 2.94E-06 20-Nov R.GLGLDDALEPR[166.11].Q "sp|Q9Y230|RUVB2_HUMAN,tr|M0R0Z0|M0R0Z0_HUMAN,tr|A0A1W2PS48|A0A1W2PS48_HUMAN,tr|X6R2L4|X6R2L4_HUMAN" 4 1164.6014 1.33 16766 17213 2 1164.599407 583.308 RuvB-like 2 OS=Homo sapiens OX=9606 GN=RUVBL2 PE=1 SV=3 4.03 3172 - 3.61E+06 - - - -1.7302 - 2.222 0.535 - 444.4 1 2 0 -0.002 11 0 0 0 1.50E+08 1.13E+08 - - - 5.1518 0.9997 221125_WJC_METTL3_EV_vs_WT_F02.17214.17214.2 0.00194 18-Aug K.AEEVATFFAK.M sp|P11387|TOP1_HUMAN 1 1111.555 0.61 16767 17214 2 1111.55352 556.7848 DNA topoisomerase 1 OS=Homo sapiens OX=9606 GN=TOP1 PE=1 SV=2 4.53 3172.1 - 2.69E+06 - - - -1.3099 - 1.906 0.418 - 231.8 1 2 0 -0.0015 10 0 0 0 5.08E+07 8.29E+07 - - - 3.9283 0.9995 221125_WJC_METTL3_EV_vs_WT_F02.17216.17216.2 0.00148 22-Jul R.ITSGPFEPDLYK.S sp|Q9UQ80|PA2G4_HUMAN 1 1365.6816 0.14 16769 17216 2 1365.684281 683.8481 Proliferation-associated protein 2G4 OS=Homo sapiens OX=9606 GN=PA2G4 PE=1 SV=3 4.37 3172.3 - 733567 - - - 1.939 - 1.808 0.46 - 157.3 1 2 0 0.0026 12 0 0 0 2.25E+07 1.56E+08 - - - 3.996 0.9999 221125_WJC_METTL3_EV_vs_WT_F02.17221.17221.2 2.30E-05 15/22 K.WMEEQAQSLIDK[136.11].T "sp|P09234|RU1C_HUMAN,tr|A0A0A0MRR7|A0A0A0MRR7_HUMAN" 2 1484.7061 1.61 16772 17221 2 1484.706269 743.3603 U1 small nuclear ribonucleoprotein C OS=Homo sapiens OX=9606 GN=SNRPC PE=1 SV=1 4.14 3172.9 - 2.10E+06 - - - 0.1273 - 2.727 0.539 - 855.1 1 2 0 0.0002 12 0 0 0 6.84E+07 4.26E+07 - - - 5.6616 0.9999 221125_WJC_METTL3_EV_vs_WT_F02.17223.17223.2 2.90E-06 20-Dec K.TVFGVEPDLTR[166.11].E sp|Q96KP4|CNDP2_HUMAN 1 1242.6484 0.61 16774 17223 2 1242.648389 622.3315 Cytosolic non-specific dipeptidase OS=Homo sapiens OX=9606 GN=CNDP2 PE=1 SV=2 4.37 3173.1 - 711215 - - - 0.0137 - 2.245 0.496 - 491.6 1 2 0 0 11 0 0 0 2.29E+07 3.73E+07 - - - 4.8922 0.9998 221125_WJC_METTL3_EV_vs_WT_F02.17224.17224.2 0.00472 22-Oct R.LLETC[160.03]SIALVGK.Y "sp|P17812|PYRG1_HUMAN,tr|A0A3B3ITF6|A0A3B3ITF6_HUMAN,tr|B4E1E0|B4E1E0_HUMAN,tr|A0A3B3IRQ8|A0A3B3IRQ8_HUMAN,tr|A0A3B3ITB8|A0A3B3ITB8_HUMAN,tr|A0A3B3IRI2|A0A3B3IRI2_HUMAN,tr|A0A3B3ISY3|A0A3B3ISY3_HUMAN" 7 1302.7217 0.38 16775 17224 2 1302.722371 652.3681 CTP synthase 1 OS=Homo sapiens OX=9606 GN=CTPS1 PE=1 SV=2 5.99 3173.3 - 577997 - - - 0.4967 - 1.665 0.493 - 236.9 1 2 0 0.0006 12 0 0 0 2.60E+06 6.90E+06 - - - 4.0235 0.9959 221125_WJC_METTL3_EV_vs_WT_F02.17227.17227.2 5.99 16-Oct R.NLQLIQSIR.D "sp|Q86UK7|ZN598_HUMAN,tr|H3BQQ2|H3BQQ2_HUMAN,tr|H3BPG6|H3BPG6_HUMAN" 3 1083.64 0.52 16777 17227 2 1083.641009 542.8273 E3 ubiquitin-protein ligase ZNF598 OS=Homo sapiens OX=9606 GN=ZNF598 PE=1 SV=1 9.75 3173.6 - 646789 - - - 0.8914 - 1.787 0.094 - 334.7 1 2 0 0.001 9 0 0 0 1.15E+07 2.22E+07 - - - 1.4145 0.998 221125_WJC_METTL3_EV_vs_WT_F02.17228.17228.2 0.00171 14-Aug K.NLYIISVK.G "sp|P62829|RL23_HUMAN,tr|J3KT29|J3KT29_HUMAN,tr|B9ZVP7|B9ZVP7_HUMAN,tr|C9JD32|C9JD32_HUMAN" 4 948.5644 1 16778 17228 2 948.563355 475.2895 60S ribosomal protein L23 OS=Homo sapiens OX=9606 GN=RPL23 PE=1 SV=1 8.59 3173.6 - 2.85E+07 - - - -1.1206 - 1.501 0.231 - 270.2 1 2 0 -0.0011 8 0 0 0 1.09E+09 1.09E+09 - - - 1.9717 0.9992 221125_WJC_METTL3_EV_vs_WT_F02.17230.17230.2 0.857 16-Nov R.NLQLIQSIR[166.11].D "sp|Q86UK7|ZN598_HUMAN,tr|H3BQQ2|H3BQQ2_HUMAN,tr|H3BPG6|H3BPG6_HUMAN" 3 1093.6483 0.52 16780 17230 2 1093.647318 547.8314 E3 ubiquitin-protein ligase ZNF598 OS=Homo sapiens OX=9606 GN=ZNF598 PE=1 SV=1 9.75 3173.8 - 1.51E+06 - - - -0.9098 - 2.076 0.204 - 484.6 1 2 0 -0.001 9 0 0 0 1.15E+07 2.20E+07 - - - 2.6606 0.9999 221125_WJC_METTL3_EV_vs_WT_F02.17236.17236.2 1.27E-05 20-Nov R.NELESYAYSLK.N "sp|P11021|BIP_HUMAN,tr|A0A7P0TB36|A0A7P0TB36_HUMAN,tr|A0A7P0TAI0|A0A7P0TAI0_HUMAN" 3 1315.6296 0.55 16784 17236 2 1315.629014 658.8221 Endoplasmic reticulum chaperone BiP OS=Homo sapiens OX=9606 GN=HSPA5 PE=1 SV=2 4.53 3174.6 - 1.30E+07 - - - -0.4431 - 2.042 0.49 - 552.5 1 2 0 -0.0006 11 0 0 0 2.54E+08 4.58E+08 - - - 4.5913 0.9999 221125_WJC_METTL3_EV_vs_WT_F02.17237.17237.2 0.000121 20-Dec R.GLGLDDALEPR.Q "sp|Q9Y230|RUVB2_HUMAN,tr|M0R0Z0|M0R0Z0_HUMAN,tr|A0A1W2PS48|A0A1W2PS48_HUMAN,tr|X6R2L4|X6R2L4_HUMAN" 4 1154.5932 1.33 16785 17237 2 1154.592964 578.3039 RuvB-like 2 OS=Homo sapiens OX=9606 GN=RUVBL2 PE=1 SV=3 4.03 3174.6 - 3.87E+06 - - - -0.1628 - 2.254 0.471 - 579.4 1 2 0 -0.0002 11 0 0 0 1.50E+08 1.13E+08 - - - 4.7183 0.9997 221125_WJC_METTL3_EV_vs_WT_F02.17238.17238.2 8.94E-05 20-Nov K.GPLQSVQVFGR[166.11].K "sp|P62249|RS16_HUMAN,tr|M0R210|M0R210_HUMAN,tr|M0R3H0|M0R3H0_HUMAN,tr|Q6IPX4|Q6IPX4_HUMAN" 4 1196.6541 0.58 16786 17238 2 1196.655333 599.3343 40S ribosomal protein S16 OS=Homo sapiens OX=9606 GN=RPS16 PE=1 SV=2 9.75 3174.7 - 3.83E+06 - - - 1.0086 - 1.825 0.439 - 384.5 1 2 0 0.0012 11 0 0 0 1.79E+09 3.07E+09 - - - 3.9105 0.9999 221125_WJC_METTL3_EV_vs_WT_F02.17240.17240.3 0.000134 Dec-36 R.ILIAKPIMFR.G "sp|Q9UN86|G3BP2_HUMAN,tr|A0A7I2V647|A0A7I2V647_HUMAN,tr|A0A7I2YQD9|A0A7I2YQD9_HUMAN,tr|A0A7I2V3P9|A0A7I2V3P9_HUMAN" 4 1200.7417 1.2 16788 17240 3 1200.739537 401.2545 Ras GTPase-activating protein-binding protein 2 OS=Homo sapiens OX=9606 GN=G3BP2 PE=1 SV=2 11 3174.9 - 1.15E+06 - - - -1.7772 - 2.069 0.477 - 158.3 1 2 0 -0.0021 10 0 0 0 7.12E+07 5.91E+07 - - - 5.9808 0.9998 221125_WJC_METTL3_EV_vs_WT_F02.17244.17244.3 0.000602 Nov-44 K.LIVAYVDDLDRR.G "sp|O14776|TCRG1_HUMAN,tr|A0A7P0T8N8|A0A7P0T8N8_HUMAN" 2 1446.7831 0.63 16790 17244 3 1446.780707 483.2683 Transcription elongation regulator 1 OS=Homo sapiens OX=9606 GN=TCERG1 PE=1 SV=2 4.43 3175.6 - 865291 - - - -1.6388 - 2.044 0.376 - 140.2 1 2 0 -0.0024 12 0 0 0 1.85E+07 2.94E+07 - - - 4.713 0.9997 221125_WJC_METTL3_EV_vs_WT_F02.17246.17246.2 0.000564 18-Oct R.FVNLGIEPPK.G "sp|P35998|PRS7_HUMAN,tr|C9JX88|C9JX88_HUMAN" 2 1112.623 0.71 16792 17246 2 1112.622752 557.3188 26S proteasome regulatory subunit 7 OS=Homo sapiens OX=9606 GN=PSMC2 PE=1 SV=3 6 3175.8 - 1.31E+06 - - - -0.2193 - 1.674 0.425 - 318.1 1 2 0 -0.0002 10 0 0 0 3.41E+07 4.78E+07 - - - 3.6181 0.9999 221125_WJC_METTL3_EV_vs_WT_F02.17247.17247.2 7.06E-06 24-Dec K.LIAQNLELNETIK.L "sp|P52732|KIF11_HUMAN,tr|A0A7I2V3A9|A0A7I2V3A9_HUMAN" 2 1497.8403 4.62 16793 17247 2 1497.838916 749.9274 Kinesin-like protein KIF11 OS=Homo sapiens OX=9606 GN=KIF11 PE=1 SV=2 4.53 3175.9 - 977199 - - - -0.8966 - 2.623 0.551 - 378.1 1 2 0 -0.0013 13 0 0 0 5.95E+07 1.29E+07 - - - 5.5852 0.9243 221125_WJC_METTL3_EV_vs_WT_F02.17248.17248.2 0.0247 14-Sep Y.LEVSQILK[136.11].K "sp|Q06278|AOXA_HUMAN,sp|Q08722|CD47_HUMAN,tr|A0A2R8Y484|A0A2R8Y484_HUMAN" 3 936.5735 0.88 16794 17248 2 936.571704 469.294 Aldehyde oxidase OS=Homo sapiens OX=9606 GN=AOX1 PE=1 SV=2 6 3176 - 877330 - - - -1.9529 - 1.676 0.293 - 182.7 1 1 0 -0.0018 8 0 0 0 4.68E+07 5.30E+07 - - - 2.762 0.9665 221125_WJC_METTL3_EV_vs_WT_F02.17255.17255.2 1.9 12-May R.DILSFDK.L sp|Q14151|SAFB2_HUMAN 1 836.428 1.49 16799 17255 2 836.426741 419.2213 Scaffold attachment factor B2 OS=Homo sapiens OX=9606 GN=SAFB2 PE=1 SV=1 4.21 3176.8 - 3.03E+06 - - - -1.4861 - 1.186 0.088 - 82 2 2 0 -0.0012 7 0 0 0 5.67E+07 3.81E+07 - - - 0.0966 0.9959 221125_WJC_METTL3_EV_vs_WT_F02.17261.17261.3 0.0795 Oct-40 R.LALSLFRPGGR.A sp|Q9H7N4|SFR19_HUMAN 1 1185.6982 1.74 16803 17261 3 1185.698155 396.24 "Splicing factor, arginine\serine-rich 19 OS=Homo sapiens OX=9606 GN=SCAF1 PE=1 SV=3" 12 3177.5 - 848375 - - - -0.0599 - 1.789 0.195 - 123.2 1 2 0 -0.0001 11 0 0 0 2.22E+07 1.27E+07 - - - 2.3664 1 221125_WJC_METTL3_EV_vs_WT_F02.17262.17262.2 8.45E-06 15/24 K.LIAQNLELNETIK[136.11].L "sp|P52732|KIF11_HUMAN,tr|A0A7I2V3A9|A0A7I2V3A9_HUMAN" 2 1505.8545 4.56 16804 17262 2 1505.85436 753.9345 Kinesin-like protein KIF11 OS=Homo sapiens OX=9606 GN=KIF11 PE=1 SV=2 4.53 3177.7 - 649110 - - - -0.0657 - 2.961 0.576 - 684.5 1 2 0 -0.0001 13 0 0 0 5.95E+07 1.30E+07 - - - 6.0813 0.9992 221125_WJC_METTL3_EV_vs_WT_F02.17263.17263.2 1.01E-05 18-Sep K.SMFAGVPTMR[166.11].E "sp|O15260|SURF4_HUMAN,tr|B7Z1G8|B7Z1G8_HUMAN,tr|Q5T8U5|Q5T8U5_HUMAN" 3 1105.5288 0.82 16805 17263 2 1105.526878 553.7717 Surfeit locus protein 4 OS=Homo sapiens OX=9606 GN=SURF4 PE=1 SV=3 9.47 3177.8 - 593465 - - - -1.7304 - 1.796 0.341 - 269.7 1 2 0 -0.0019 10 0 0 0 2.57E+07 3.12E+07 - - - 3.1935 0.9563 221125_WJC_METTL3_EV_vs_WT_F02.17264.17264.2 0.405 16-Aug K.SLDYLNLDK.M sp|Q96GV9|MACIR_HUMAN 1 1079.5499 2.71 16806 17264 2 1079.546966 540.7822 Macrophage immunometabolism regulator OS=Homo sapiens OX=9606 GN=MACIR PE=1 SV=1 4.21 3177.9 - 559594 - - - -2.7085 - 1.054 0.173 - 135.5 1 2 0 -0.0029 9 0 0 0 1.25E+07 4.61E+06 - - - 0.47 0.9931 221125_WJC_METTL3_EV_vs_WT_F02.17265.17265.3 0.0026 13/36 R.IPELLSLRPR.P "sp|Q9BTD8|RBM42_HUMAN,tr|K7EQ03|K7EQ03_HUMAN,tr|K7ER08|K7ER08_HUMAN,tr|K7EP90|K7EP90_HUMAN" 4 1192.7292 1.32 16807 17265 3 1192.726995 398.5837 RNA-binding protein 42 OS=Homo sapiens OX=9606 GN=RBM42 PE=1 SV=1 9.6 3178 - 682459 - - - -1.842 - 2.256 0.468 - 193.9 1 1 0 -0.0022 10 0 0 0 2.95E+07 2.24E+07 - - - 6.1332 0.9999 221125_WJC_METTL3_EV_vs_WT_F02.17270.17270.3 0.000233 Oct-36 R.ILIAK[136.11]PIMFR[166.11].G "sp|Q9UN86|G3BP2_HUMAN,tr|A0A7I2V647|A0A7I2V647_HUMAN,tr|A0A7I2YQD9|A0A7I2YQD9_HUMAN,tr|A0A7I2V3P9|A0A7I2V3P9_HUMAN" 4 1218.7641 1.21 16810 17270 3 1218.763364 407.262 Ras GTPase-activating protein-binding protein 2 OS=Homo sapiens OX=9606 GN=G3BP2 PE=1 SV=2 11 3178.6 - 2.99E+06 - - - -0.6375 - 1.766 0.44 - 108.2 1 2 0 -0.0008 10 0 0 0 7.14E+07 5.91E+07 - - - 5.1063 0.847 221125_WJC_METTL3_EV_vs_WT_F02.17271.17271.2 0.126 16-Jul W.TGLVGDLLR.G sp|Q8TCU5|NMD3A_HUMAN 1 942.5498 3.19 16811 17271 2 942.550923 472.2822 "Glutamate receptor ionotropic, NMDA 3A OS=Homo sapiens OX=9606 GN=GRIN3A PE=1 SV=2" 5.5 3178.7 - 672986 - - - 1.1586 - 1.483 0.213 - 109.6 1 1 0 0.0011 9 0 0 0 1.43E+07 4.48E+06 - - - 1.7539 0.9981 221125_WJC_METTL3_EV_vs_WT_F02.17273.17273.2 0.0924 18-Oct K.DVLEVGELAK[136.11].L "sp|Q9GZZ1|NAA50_HUMAN,tr|C9JZU6|C9JZU6_HUMAN,tr|E7EQ69|E7EQ69_HUMAN,tr|C9J5D1|C9J5D1_HUMAN" 4 1079.5954 0.98 16813 17273 2 1079.596918 540.805 N-alpha-acetyltransferase 50 OS=Homo sapiens OX=9606 GN=NAA50 PE=1 SV=1 4.14 3179 - 588349 - - - 1.4144 - 1.575 0.264 - 246.6 1 2 0 0.0015 10 0 0 0 1.18E+07 1.20E+07 - - - 2.2584 0.9994 221125_WJC_METTL3_EV_vs_WT_F02.17274.17274.2 7.94E-05 26-Aug R.LFPPDDSPLPVSSR.V "sp|Q05519|SRS11_HUMAN,tr|Q5T760|Q5T760_HUMAN,tr|B4DWT1|B4DWT1_HUMAN" 3 1525.7777 2.59 16814 17274 2 1525.779925 763.8961 Serine\arginine-rich splicing factor 11 OS=Homo sapiens OX=9606 GN=SRSF11 PE=1 SV=1 4.21 3179.1 - 547451 - - - 1.4851 - 1.602 0.421 - 87.8 1 2 0 0.0023 14 0 0 0 2.53E+07 9.74E+06 - - - 3.3324 0.9998 221125_WJC_METTL3_EV_vs_WT_F02.17275.17275.3 0.000523 Sep-36 K.LEHWYITGLR[166.11].Q sp|Q709C8|VP13C_HUMAN 1 1296.6854 3.76 16815 17275 3 1296.686786 433.2358 Vacuolar protein sorting-associated protein 13C OS=Homo sapiens OX=9606 GN=VPS13C PE=1 SV=1 6.75 3179.2 - 465465 - - - 1.0481 - 1.835 0.376 - 109.5 1 2 0 0.0014 10 0 0 0 1.73E+07 4.61E+06 - - - 4.5045 0.9974 221125_WJC_METTL3_EV_vs_WT_F02.17278.17278.2 0.0542 14-Aug K.LWNLNNYR[166.11].T "sp|Q6P2Q9|PRP8_HUMAN,tr|I3L3Z8|I3L3Z8_HUMAN" 2 1101.5595 1.51 16816 17278 2 1101.56016 551.787 Pre-mRNA-processing-splicing factor 8 OS=Homo sapiens OX=9606 GN=PRPF8 PE=1 SV=2 8.75 3179.6 - 2.39E+06 - - - 0.601 - 1.677 0.146 - 260.4 1 2 0 0.0007 8 0 0 0 1.01E+08 6.63E+07 - - - 1.6784 0.9948 221125_WJC_METTL3_EV_vs_WT_F02.17279.17279.2 0.44 14-Jul K.DLFTC[160.03]TIK[136.11].R sp|Q86VP6|CAND1_HUMAN 1 1004.5092 0.78 16817 17279 2 1004.507973 503.2619 Cullin-associated NEDD8-dissociated protein 1 OS=Homo sapiens OX=9606 GN=CAND1 PE=1 SV=2 5.83 3179.7 - 639196 - - - -1.2394 - 1.309 0.194 - 152 1 2 0 -0.0012 8 0 0 0 1.37E+07 1.75E+07 - - - 1.2856 0.9996 221125_WJC_METTL3_EV_vs_WT_F02.17280.17280.2 0.000671 18-Aug R.VVQVWFQNTR[166.11].A "sp|Q9C0A1|ZFHX2_HUMAN,sp|Q86UP3|ZFHX4_HUMAN,sp|Q15911|ZFHX3_HUMAN,tr|E7EVZ1|E7EVZ1_HUMAN" 4 1285.6807 0.001 16818 17280 2 1285.679666 643.8476 Zinc finger homeobox protein 2 OS=Homo sapiens OX=9606 GN=ZFHX2 PE=1 SV=3 9.72 3179.8 - 668129 - - - -0.7856 - 1.628 0.402 - 184.9 1 2 0 -0.001 10 0 0 0 0.00E+00 1.47E+07 - - - 3.3702 0.9997 221125_WJC_METTL3_EV_vs_WT_F02.17282.17282.2 0.000542 14-Jul R.YFTWDPSR[166.11].F "sp|Q14697|GANAB_HUMAN,tr|E9PKU7|E9PKU7_HUMAN,tr|F5H6X6|F5H6X6_HUMAN" 3 1080.4904 0.91 16820 17282 2 1080.490197 541.2525 Neutral alpha-glucosidase AB OS=Homo sapiens OX=9606 GN=GANAB PE=1 SV=3 5.84 3180 - 655060 - - - -0.2018 - 1.363 0.467 - 162.8 1 2 0 -0.0002 8 0 0 0 1.60E+07 1.77E+07 - - - 3.4242 0.9998 221125_WJC_METTL3_EV_vs_WT_F02.17285.17285.2 0.00202 20-Oct R.LWDLTTGTTTR[166.11].R "sp|P63244|RACK1_HUMAN,tr|D6RFX4|D6RFX4_HUMAN,tr|D6RFZ9|D6RFZ9_HUMAN,tr|D6RAU2|D6RAU2_HUMAN,tr|H0YAF8|H0YAF8_HUMAN,tr|D6R9Z1|D6R9Z1_HUMAN,tr|J3KPE3|J3KPE3_HUMAN,tr|D6R9L0|D6R9L0_HUMAN,tr|D6RHH4|D6RHH4_HUMAN,tr|E9PD14|E9PD14_HUMAN,tr|H0Y8W2|H0Y8W2_HUMAN" 11 1273.6542 1.26 16821 17285 2 1273.654591 637.8344 Receptor of activated protein C kinase 1 OS=Homo sapiens OX=9606 GN=RACK1 PE=1 SV=3 5.84 3180.4 - 5.63E+06 - - - 0.318 - 2.098 0.406 - 413.2 1 2 0 0.0004 11 0 0 0 1.28E+08 1.01E+08 - - - 4.0441 0.9969 221125_WJC_METTL3_EV_vs_WT_F02.17286.17286.2 0.363 16-Sep K.VDLIELSEK[136.11].C sp|Q69YN4|VIR_HUMAN 1 1052.5845 1.87 16822 17286 2 1052.581669 527.2995 Protein virilizer homolog OS=Homo sapiens OX=9606 GN=VIRMA PE=1 SV=2 4.14 3180.5 - 1.72E+06 - - - -2.682 - 1.98 0.199 - 285 1 2 0 -0.0028 9 0 0 0 3.48E+07 1.86E+07 - - - 2.4862 0.997 221125_WJC_METTL3_EV_vs_WT_F02.17287.17287.2 0.000143 18-Oct K.EMIFEDTNLK.L "sp|P18031|PTN1_HUMAN,tr|B4DSN5|B4DSN5_HUMAN" 2 1238.5853 0.68 16823 17287 2 1238.580032 620.2999 Tyrosine-protein phosphatase non-receptor type 1 OS=Homo sapiens OX=9606 GN=PTPN1 PE=1 SV=1 4.14 3180.6 - 1.26E+06 - - - -4.2452 - 1.774 0.414 - 306.4 1 2 0 -0.0053 10 0 0 0 2.03E+07 3.00E+07 - - - 3.6972 0.9999 221125_WJC_METTL3_EV_vs_WT_F02.17288.17288.2 2.21E-05 18-Oct K.EMIFEDTNLK[136.11].L "sp|P18031|PTN1_HUMAN,tr|B4DSN5|B4DSN5_HUMAN" 2 1246.5995 1.15 16824 17288 2 1246.600191 624.307 Tyrosine-protein phosphatase non-receptor type 1 OS=Homo sapiens OX=9606 GN=PTPN1 PE=1 SV=1 4.14 3180.6 - 1.11E+06 - - - 0.5623 - 1.993 0.522 - 437.7 1 2 0 0.0007 10 0 0 0 3.24E+07 2.82E+07 - - - 4.8213 0.9735 221125_WJC_METTL3_EV_vs_WT_F02.17290.17290.2 0.945 14-Jun R.WTFEEGIK.R sp|Q86UA1|PRP39_HUMAN 1 1008.4916 1.51 16826 17290 2 1008.491819 505.2531 Pre-mRNA-processing factor 39 OS=Homo sapiens OX=9606 GN=PRPF39 PE=1 SV=3 4.53 3180.8 - 626640 - - - 0.1706 - 0.992 0.131 - 76.6 1 2 0 0.0002 8 0 0 0 1.21E+07 8.00E+06 - - - -0.0157 0.9999 221125_WJC_METTL3_EV_vs_WT_F02.17292.17292.2 9.12E-06 24-Dec K.IVQLLGQNEVDYR.Q "sp|Q9BZX2|UCK2_HUMAN,tr|A0A2R8Y653|A0A2R8Y653_HUMAN" 2 1545.8151 0.73 16828 17292 2 1545.813389 773.9148 Uridine-cytidine kinase 2 OS=Homo sapiens OX=9606 GN=UCK2 PE=1 SV=1 4.37 3181 - 370810 - - - -1.1114 - 2.731 0.494 - 574.4 1 2 0 -0.0017 13 0 0 0 8.85E+06 1.21E+07 - - - 5.2677 0.9989 221125_WJC_METTL3_EV_vs_WT_F02.17293.17293.3 0.0156 Nov-40 K.LQAILKPMMLR.R "sp|Q9P2D1|CHD7_HUMAN,sp|Q9HCK8|CHD8_HUMAN,sp|Q3L8U1|CHD9_HUMAN,tr|H3BTW3|H3BTW3_HUMAN,tr|A0A2R8Y840|A0A2R8Y840_HUMAN,tr|H0YJG4|H0YJG4_HUMAN,tr|A0A2R8Y4P3|A0A2R8Y4P3_HUMAN" 7 1312.7723 0.94 16829 17293 3 1312.77222 438.598 Chromodomain-helicase-DNA-binding protein 7 OS=Homo sapiens OX=9606 GN=CHD7 PE=1 SV=3 11 3181.2 - 290755 - - - -0.0754 - 1.763 0.275 - 174.9 1 2 0 -0.0001 11 0 0 0 4.60E+06 4.87E+06 - - - 3.2167 0.9999 221125_WJC_METTL3_EV_vs_WT_F02.17296.17296.2 4.68E-05 20-Nov R.LWDLTTGTTTR.R "sp|P63244|RACK1_HUMAN,tr|D6RFX4|D6RFX4_HUMAN,tr|D6RFZ9|D6RFZ9_HUMAN,tr|D6RAU2|D6RAU2_HUMAN,tr|H0YAF8|H0YAF8_HUMAN,tr|D6R9Z1|D6R9Z1_HUMAN,tr|J3KPE3|J3KPE3_HUMAN,tr|D6R9L0|D6R9L0_HUMAN,tr|D6RHH4|D6RHH4_HUMAN,tr|E9PD14|E9PD14_HUMAN,tr|H0Y8W2|H0Y8W2_HUMAN" 11 1263.6459 1.26 16830 17296 2 1263.646219 632.8302 Receptor of activated protein C kinase 1 OS=Homo sapiens OX=9606 GN=RACK1 PE=1 SV=3 5.84 3181.6 - 6.36E+06 - - - 0.2398 - 2.154 0.53 - 490.8 1 2 0 0.0003 11 0 0 0 1.28E+08 1.01E+08 - - - 5.0313 0.9875 221125_WJC_METTL3_EV_vs_WT_F02.17297.17297.2 0.974 14-Jul R.TMVQLFEK.G sp|P08240|SRPRA_HUMAN 1 994.5158 0.28 16831 17297 2 994.515042 498.2652 Signal recognition particle receptor subunit alpha OS=Homo sapiens OX=9606 GN=SRPRA PE=1 SV=2 5.66 3181.6 - 862273 - - - -0.7149 - 1.136 0.148 - 131.6 1 2 0 -0.0007 8 0 0 0 1.85E+07 6.60E+07 - - - 0.5185 0.9904 221125_WJC_METTL3_EV_vs_WT_F02.17298.17298.2 0.159 14-Jun R.FEVNPVWK[136.11].K "sp|P17812|PYRG1_HUMAN,tr|B4E1E0|B4E1E0_HUMAN,tr|A0A3B3IRI2|A0A3B3IRI2_HUMAN" 3 1025.5426 0.82 16832 17298 2 1025.540129 513.7786 CTP synthase 1 OS=Homo sapiens OX=9606 GN=CTPS1 PE=1 SV=2 6 3181.7 - 1.43E+06 - - - -2.3773 - 1.421 0.202 - 92.5 3 2 0 -0.0024 8 0 0 0 2.07E+07 2.52E+07 - - - 1.3788 0.9997 221125_WJC_METTL3_EV_vs_WT_F02.17299.17299.2 0.00184 18-Aug K.SMFAGVPTMR.E "sp|O15260|SURF4_HUMAN,tr|B7Z1G8|B7Z1G8_HUMAN,tr|Q5T8U5|Q5T8U5_HUMAN" 3 1095.5205 0.86 16833 17299 2 1095.521214 548.7675 Surfeit locus protein 4 OS=Homo sapiens OX=9606 GN=SURF4 PE=1 SV=3 9.47 3181.8 - 1.39E+06 - - - 0.6326 - 1.799 0.417 - 268.2 1 2 0 0.0007 10 0 0 0 2.55E+07 2.97E+07 - - - 3.7599 0.996 221125_WJC_METTL3_EV_vs_WT_F02.17300.17300.2 0.124 14-Aug R.TVLNQILR[166.11].Q "sp|Q7Z6Z7|HUWE1_HUMAN,tr|H0Y659|H0Y659_HUMAN" 2 965.5897 11.51 16834 17300 2 965.589745 483.8021 E3 ubiquitin-protein ligase HUWE1 OS=Homo sapiens OX=9606 GN=HUWE1 PE=1 SV=3 9.41 3181.9 - 920641 - - - 0.0104 - 1.501 0.135 - 223.8 1 2 0 0 8 0 0 0 3.93E+08 3.42E+07 - - - 1.263 0.9882 221125_WJC_METTL3_EV_vs_WT_F02.17301.17301.2 0.000425 18-Sep R.PIFGLTSNYK[136.11].G "sp|Q96ST2|IWS1_HUMAN,tr|A0A1B0GW95|A0A1B0GW95_HUMAN" 2 1146.6165 12.39 16835 17301 2 1146.617087 574.3155 Protein IWS1 homolog OS=Homo sapiens OX=9606 GN=IWS1 PE=1 SV=2 9.01 3182 - 586594 - - - 0.5468 - 2.044 0.433 - 192 1 1 0 0.0006 10 0 0 0 1.86E+08 1.50E+07 - - - 4.2345 0.9637 221125_WJC_METTL3_EV_vs_WT_F02.17302.17302.2 0.51 12-Jul K.DIVNLYR[166.11].H sp|Q6V1P9|PCD23_HUMAN 1 901.4897 0.73 16836 17302 2 901.487203 451.7521 Protocadherin-23 OS=Homo sapiens OX=9606 GN=DCHS2 PE=2 SV=2 5.84 3182.1 - 580832 - - - -2.7554 - 1.554 0.025 - 172.6 1 2 0 -0.0025 7 0 0 0 1.50E+07 2.06E+07 - - - 0.6217 0.9634 221125_WJC_METTL3_EV_vs_WT_F02.17303.17303.3 0.00194 14/40 K.PLR[166.11]LPLQDVYK[136.11].L "sp|Q05639|EF1A2_HUMAN,sp|P68104|EF1A1_HUMAN,sp|Q5VTE0|EF1A3_HUMAN,tr|A0A7I2V659|A0A7I2V659_HUMAN,tr|A0A7I2V3H3|A0A7I2V3H3_HUMAN,tr|A0A2U3TZH3|A0A2U3TZH3_HUMAN,tr|A0A7I2V5N4|A0A7I2V5N4_HUMAN,tr|A0A087WVQ9|A0A087WVQ9_HUMAN,tr|A0A087WV01|A0A087WV01_HUMAN" 9 1358.8041 0.41 16837 17303 3 1358.805712 453.942 Elongation factor 1-alpha 2 OS=Homo sapiens OX=9606 GN=EEF1A2 PE=1 SV=1 9 3182.2 - 511065 - - - 1.1922 - 2.545 0.398 - 211.9 1 1 1 0.0016 11 0 0 0 1.09E+07 2.67E+07 - - - 5.6306 0.9996 221125_WJC_METTL3_EV_vs_WT_F02.17306.17306.2 0.000577 20-Sep K.FSPAGPVLSIR[166.11].V "sp|Q13310|PABP4_HUMAN,tr|B1ANR0|B1ANR0_HUMAN,tr|A0A7I2V4L7|A0A7I2V4L7_HUMAN,tr|B1ANR1|B1ANR1_HUMAN" 4 1152.6531 1.22 16838 17306 2 1152.652612 577.3338 Polyadenylate-binding protein 4 OS=Homo sapiens OX=9606 GN=PABPC4 PE=1 SV=1 9.75 3182.6 - 1.19E+06 - - - -0.3921 - 1.541 0.403 - 333.8 1 2 0 -0.0005 11 0 0 0 4.93E+08 4.03E+08 - - - 3.1872 0.9991 221125_WJC_METTL3_EV_vs_WT_F02.17307.17307.2 0.00475 14-Jul R.WDDDVVFK[136.11].N sp|Q9P013|CWC15_HUMAN 1 1030.4851 0.49 16839 17307 2 1030.483789 516.2498 Spliceosome-associated protein CWC15 homolog OS=Homo sapiens OX=9606 GN=CWC15 PE=1 SV=2 3.93 3182.7 - 622467 - - - -1.2839 - 1.466 0.354 - 109 1 2 0 -0.0013 8 0 0 0 1.05E+07 2.14E+07 - - - 2.8089 0.9968 221125_WJC_METTL3_EV_vs_WT_F02.17310.17310.2 0.000318 22-Oct R.LLEEAQLQDLEK.A "sp|Q9NU22|MDN1_HUMAN,tr|Q5T795|Q5T795_HUMAN" 2 1427.7508 1.3 16842 17310 2 1427.7572 714.8827 Midasin OS=Homo sapiens OX=9606 GN=MDN1 PE=1 SV=2 4 3183.1 - 375011 - - - 4.5001 - 2.016 0.405 - 270.4 1 2 0 0.0064 12 0 0 0 1.09E+07 8.43E+06 - - - 3.8751 0.9642 221125_WJC_METTL3_EV_vs_WT_F02.17312.17312.2 0.000147 22-Oct L.FYDPYLSDGVER.A "sp|Q13363|CTBP1_HUMAN,tr|H0Y9M9|H0Y9M9_HUMAN,tr|H0Y8W7|H0Y8W7_HUMAN" 3 1459.662 0.15 16844 17312 2 1459.658885 730.8383 C-terminal-binding protein 1 OS=Homo sapiens OX=9606 GN=CTBP1 PE=1 SV=2 4.03 3183.4 - 208040 - - - -2.1067 - 1.44 0.504 - 143.1 1 1 0 -0.0031 12 0 0 0 4.94E+06 3.30E+07 - - - 3.722 0.9909 221125_WJC_METTL3_EV_vs_WT_F02.17315.17315.2 3.57E-05 20-Oct K.VLVEGPLNNLR[166.11].E sp|Q92900|RENT1_HUMAN 1 1232.7116 1.06 16845 17315 2 1232.719349 617.3631 Regulator of nonsense transcripts 1 OS=Homo sapiens OX=9606 GN=UPF1 PE=1 SV=2 5.97 3183.8 - 1.45E+06 - - - 6.2529 - 1.946 0.439 - 392.2 1 2 0 0.0077 11 0 0 0 1.06E+08 9.96E+07 - - - 4.0821 0.9999 221125_WJC_METTL3_EV_vs_WT_F02.17317.17317.2 0.00186 15/24 R.LLAENNEIISNIR[166.11].D sp|Q16706|MA2A1_HUMAN 1 1507.8234 1.04 16847 17317 2 1507.823869 754.919 Alpha-mannosidase 2 OS=Homo sapiens OX=9606 GN=MAN2A1 PE=1 SV=2 4.53 3184 - 1.06E+06 - - - 0.3263 - 2.729 0.453 - 862.8 1 2 0 0.0005 13 0 0 0 2.47E+07 2.39E+07 - - - 4.9633 1 221125_WJC_METTL3_EV_vs_WT_F02.17319.17319.2 1.35E-08 28-Dec K.LLTEC[160.03]PPMMDTEYTK[136.11].L sp|P55060|XPO2_HUMAN 1 1835.8235 0.88 16849 17319 2 1835.827508 918.919 Exportin-2 OS=Homo sapiens OX=9606 GN=CSE1L PE=1 SV=3 4.14 3184.3 - 257993 - - - 2.1859 - 2.301 0.645 - 336.3 1 2 0 0.004 15 0 0 0 8.85E+06 1.01E+07 - - - 5.8525 0.9846 221125_WJC_METTL3_EV_vs_WT_F02.17320.17320.3 0.0706 Sep-40 R.MLLAHVDLIEK.L sp|P62875|RPAB5_HUMAN 1 1280.7162 1.39 16850 17320 3 1280.712508 427.9127 "DNA-directed RNA polymerases I, II, and III subunit RPABC5 OS=Homo sapiens OX=9606 GN=POLR2L PE=1 SV=1" 5.3 3184.4 - 251752 - - - -2.9171 - 1.623 0.215 - 129.1 1 2 0 -0.0037 11 0 0 0 5.86E+06 4.20E+06 - - - 2.3117 0.9999 221125_WJC_METTL3_EV_vs_WT_F02.17322.17322.2 1.27E-06 22-Dec K.LVFLEDGTSQVR[166.11].K "sp|Q8IWC1|MA7D3_HUMAN,tr|A0A0A0MRP0|A0A0A0MRP0_HUMAN" 2 1372.7226 1.26 16851 17322 2 1372.723272 687.3686 MAP7 domain-containing protein 3 OS=Homo sapiens OX=9606 GN=MAP7D3 PE=1 SV=2 4.37 3184.6 - 3.28E+06 - - - 0.4895 - 2.666 0.441 - 647.8 1 2 0 0.0007 12 0 0 0 7.06E+07 5.58E+07 - - - 4.8781 0.9996 221125_WJC_METTL3_EV_vs_WT_F02.17325.17325.2 0.0141 18-Oct R.LSEFGLIQEK.F "sp|Q9H845|ACAD9_HUMAN,tr|A0A7P0T871|A0A7P0T871_HUMAN,tr|A0A7P0T7Z1|A0A7P0T7Z1_HUMAN,tr|A0A7P0T9N9|A0A7P0T9N9_HUMAN,tr|A0A7P0T8U3|A0A7P0T8U3_HUMAN,tr|A0A7P0TB58|A0A7P0TB58_HUMAN,tr|Q9H9W4|Q9H9W4_HUMAN,tr|H0Y8Z9|H0Y8Z9_HUMAN" 8 1162.6234 3.63 16853 17325 2 1162.624524 582.319 "Complex I assembly factor ACAD9, mitochondrial OS=Homo sapiens OX=9606 GN=ACAD9 PE=1 SV=1" 4.53 3184.9 - 1.46E+06 - - - 0.9754 - 2.08 0.321 - 254.3 1 2 0 0.0011 10 0 0 0 5.91E+08 1.63E+08 - - - 3.4558 0.9997 221125_WJC_METTL3_EV_vs_WT_F02.17326.17326.2 0.000103 20-Jul K.FSPAGPVLSIR.V "sp|Q13310|PABP4_HUMAN,tr|B1ANR0|B1ANR0_HUMAN,tr|A0A7I2V4L7|A0A7I2V4L7_HUMAN,tr|B1ANR1|B1ANR1_HUMAN" 4 1142.6448 1.22 16854 17326 2 1142.645598 572.3297 Polyadenylate-binding protein 4 OS=Homo sapiens OX=9606 GN=PABPC4 PE=1 SV=1 9.75 3184.9 - 5.61E+06 - - - 0.7036 - 1.682 0.478 - 151.3 1 2 0 0.0008 11 0 0 0 4.93E+08 4.03E+08 - - - 3.9779 1 221125_WJC_METTL3_EV_vs_WT_F02.17327.17327.3 9.97E-06 14/44 R.LPVDLAEELGHR.D "sp|P42771|CDN2A_HUMAN,tr|K7ENC6|K7ENC6_HUMAN,tr|J3QRG6|J3QRG6_HUMAN,tr|K7ES20|K7ES20_HUMAN" 4 1347.7147 2.79 16855 17327 3 1347.714991 450.2455 Cyclin-dependent kinase inhibitor 2A OS=Homo sapiens OX=9606 GN=CDKN2A PE=1 SV=2 4.65 3185.1 - 682952 - - - 0.2426 - 2.806 0.432 - 330.8 1 2 0 0.0003 12 0 0 0 2.22E+07 7.95E+06 - - - 6.2162 0.9941 221125_WJC_METTL3_EV_vs_WT_F02.17328.17328.2 7.03E-07 22-Sep L.FYDPYLSDGVER[166.11].A "sp|Q13363|CTBP1_HUMAN,tr|H0Y9M9|H0Y9M9_HUMAN,tr|H0Y8W7|H0Y8W7_HUMAN" 3 1469.6702 0.12 16856 17328 2 1469.669986 735.8424 C-terminal-binding protein 1 OS=Homo sapiens OX=9606 GN=CTBP1 PE=1 SV=2 4.03 3185.2 - 402681 - - - -0.166 - 1.813 0.625 - 255.4 1 1 0 -0.0002 12 0 0 0 4.94E+06 4.10E+07 - - - 5.2227 0.9999 221125_WJC_METTL3_EV_vs_WT_F02.17329.17329.2 1.37E-05 28-Sep K.LLTEC[160.03]PPMMDTEYTK.L sp|P55060|XPO2_HUMAN 1 1827.8093 0.88 16857 17329 2 1827.810891 914.9119 Exportin-2 OS=Homo sapiens OX=9606 GN=CSE1L PE=1 SV=3 4.14 3185.3 - 273379 - - - 0.8732 - 1.988 0.593 - 174.5 1 2 0 0.0016 15 0 0 0 8.85E+06 1.01E+07 - - - 5.1097 0.9757 221125_WJC_METTL3_EV_vs_WT_F02.17330.17330.2 0.33 24-Sep K.AVGASFPLYEPAK.M sp|P46013|KI67_HUMAN 1 1348.7027 1.02 16858 17330 2 1348.704942 675.3586 Proliferation marker protein Ki-67 OS=Homo sapiens OX=9606 GN=MKI67 PE=1 SV=2 6.05 3185.5 - 245158 - - - 1.6601 - 1.469 0.056 - 120.4 1 2 0 0.0022 13 0 0 0 4.40E+07 4.31E+07 - - - 0.441 0.9998 221125_WJC_METTL3_EV_vs_WT_F02.17332.17332.2 1.32E-07 20-Oct R.ELAVQIYEEAR.K "sp|O00571|DDX3X_HUMAN,sp|O15523|DDX3Y_HUMAN,tr|A0A2R8YFR4|A0A2R8YFR4_HUMAN,tr|A0A2R8YCW1|A0A2R8YCW1_HUMAN,tr|A0A2R8YDH3|A0A2R8YDH3_HUMAN,tr|A0A2R8YDT5|A0A2R8YDT5_HUMAN,tr|A0A2R8Y645|A0A2R8Y645_HUMAN,tr|A0A2R8YF78|A0A2R8YF78_HUMAN,tr|A0A0D9SFB3|A0A0D9SFB3_HUMAN,tr|A0A2R8YFS5|A0A2R8YFS5_HUMAN,tr|A0A0D9SF53|A0A0D9SF53_HUMAN,tr|A0A2R8Y5G6|A0A2R8Y5G6_HUMAN,tr|A0A2R8Y7T2|A0A2R8Y7T2_HUMAN,tr|A0A0D9SG12|A0A0D9SG12_HUMAN,tr|A0A2U3TZJ9|A0A2U3TZJ9_HUMAN,tr|A0A2R8Y4A4|A0A2R8Y4A4_HUMAN" 16 1319.6721 1.27 16859 17332 2 1319.674443 660.8433 ATP-dependent RNA helicase DDX3X OS=Homo sapiens OX=9606 GN=DDX3X PE=1 SV=3 4.25 3185.8 - 1.21E+06 - - - 1.752 - 2.49 0.55 - 532 1 2 0 0.0023 11 0 0 0 2.82E+08 2.22E+08 - - - 5.5705 0.9777 221125_WJC_METTL3_EV_vs_WT_F02.17334.17334.2 0.0277 18-Aug R.LSEFGLIQEK[136.11].F "sp|Q9H845|ACAD9_HUMAN,tr|A0A7P0T871|A0A7P0T871_HUMAN,tr|A0A7P0T7Z1|A0A7P0T7Z1_HUMAN,tr|A0A7P0T9N9|A0A7P0T9N9_HUMAN,tr|A0A7P0T8U3|A0A7P0T8U3_HUMAN,tr|A0A7P0TB58|A0A7P0TB58_HUMAN,tr|Q9H9W4|Q9H9W4_HUMAN,tr|H0Y8Z9|H0Y8Z9_HUMAN" 8 1170.6376 3.54 16860 17334 2 1170.639544 586.3261 "Complex I assembly factor ACAD9, mitochondrial OS=Homo sapiens OX=9606 GN=ACAD9 PE=1 SV=1" 4.53 3186 - 3.62E+06 - - - 1.6692 - 1.58 0.025 - 151.7 1 2 0 0.002 10 0 0 0 5.93E+08 1.67E+08 - - - 0.5018 0.9993 221125_WJC_METTL3_EV_vs_WT_F02.17337.17337.2 0.0234 14-Sep R.SDSLLSFR[166.11].L sp|Q00587|BORG5_HUMAN 1 933.4795 1.43 16863 17337 2 933.480484 467.747 Cdc42 effector protein 1 OS=Homo sapiens OX=9606 GN=CDC42EP1 PE=1 SV=1 5.55 3186.3 - 1.30E+06 - - - 1.037 - 2.046 0.24 - 494.7 1 2 0 0.001 8 0 0 0 5.03E+07 3.53E+07 - - - 2.9724 0.9999 221125_WJC_METTL3_EV_vs_WT_F02.17338.17338.2 0.000111 14-Aug R.WDDDVVFK.N sp|Q9P013|CWC15_HUMAN 1 1022.4709 0.53 16864 17338 2 1022.471461 512.2427 Spliceosome-associated protein CWC15 homolog OS=Homo sapiens OX=9606 GN=CWC15 PE=1 SV=2 3.93 3186.4 - 859561 - - - 0.5369 - 1.646 0.564 - 218.8 1 2 0 0.0005 8 0 0 0 1.02E+07 1.93E+07 - - - 4.7095 0.9782 221125_WJC_METTL3_EV_vs_WT_F02.17339.17339.2 0.973 12-Jul R.TELFDLK[136.11].T "sp|Q13948|CASP_HUMAN,sp|P39880|CUX1_HUMAN,tr|A0A2R8Y8D0|A0A2R8Y8D0_HUMAN,tr|A0A2R8Y852|A0A2R8Y852_HUMAN,tr|A0A2R8YDI1|A0A2R8YDI1_HUMAN" 5 872.4735 1.33 16865 17339 2 872.471523 437.244 Protein CASP OS=Homo sapiens OX=9606 GN=CUX1 PE=1 SV=2 4.37 3186.5 - 578503 - - - -2.2476 - 1.37 0.093 - 270.2 1 2 0 -0.002 7 0 0 0 1.02E+08 7.63E+07 - - - 0.7248 1 221125_WJC_METTL3_EV_vs_WT_F02.17340.17340.2 6.88E-07 24-Nov K.MTMYADEVESQLK.N sp|Q53F19|NCBP3_HUMAN 1 1543.6898 0.08 16866 17340 2 1543.68891 772.8522 Nuclear cap-binding protein subunit 3 OS=Homo sapiens OX=9606 GN=NCBP3 PE=1 SV=2 4.14 3186.6 - 387188 - - - -0.5966 - 2.128 0.703 - 310 1 2 0 -0.0009 13 0 0 0 6.19E+06 8.07E+07 - - - 6.1713 0.9999 221125_WJC_METTL3_EV_vs_WT_F02.17341.17341.2 4.67E-08 Sep-36 K.GSLGGGFSSGGFSGGSFSR.G "sp|P13645|K1C10_HUMAN,tr|A0A1B0GVI3|A0A1B0GVI3_HUMAN" 2 1706.7649 999 16867 17341 2 1706.763027 854.3897 "Keratin, type I cytoskeletal 10 OS=Homo sapiens OX=9606 GN=KRT10 PE=1 SV=6" 9.75 3186.7 - 245880 - - - -1.0751 - 2.163 0.619 - 151.5 1 2 0 -0.0018 19 0 0 0 7.01E+06 0.00E+00 - - - 5.5091 0.9994 221125_WJC_METTL3_EV_vs_WT_F02.17346.17346.2 0.00903 14-Sep R.SDSLLSFR.L sp|Q00587|BORG5_HUMAN 1 923.4712 1.52 16871 17346 2 923.471628 462.7429 Cdc42 effector protein 1 OS=Homo sapiens OX=9606 GN=CDC42EP1 PE=1 SV=1 5.55 3187.2 - 2.46E+06 - - - 0.4137 - 1.847 0.268 - 429.3 1 2 0 0.0004 8 0 0 0 5.67E+07 3.72E+07 - - - 2.8708 0.999 221125_WJC_METTL3_EV_vs_WT_F02.17347.17347.2 0.0822 14-Aug K.FFVGGNWK.M sp|P60174|TPIS_HUMAN 1 953.4759 0.92 16872 17347 2 953.476254 477.7452 Triosephosphate isomerase OS=Homo sapiens OX=9606 GN=TPI1 PE=1 SV=4 8.75 3187.3 - 2.14E+06 - - - 0.3314 - 1.237 0.368 - 139.4 1 2 0 0.0003 8 0 0 0 2.66E+07 2.90E+07 - - - 2.4004 0.9991 221125_WJC_METTL3_EV_vs_WT_F02.17348.17348.2 0.000202 20-Oct R.EAPASVVPFVR[166.11].V "sp|Q53GS9|SNUT2_HUMAN,tr|F8WC91|F8WC91_HUMAN,tr|B9A018|B9A018_HUMAN" 3 1180.648 5.75 16873 17348 2 1180.650648 591.3313 U4\U6.U5 tri-snRNP-associated protein 2 OS=Homo sapiens OX=9606 GN=USP39 PE=1 SV=2 6.1 3187.4 - 1.35E+06 - - - 2.2615 - 1.959 0.349 - 398.5 1 2 0 0.0027 11 0 0 0 1.26E+08 2.19E+07 - - - 3.437 0.9993 221125_WJC_METTL3_EV_vs_WT_F02.17349.17349.2 0.261 12-Aug K.QTLDFLR.S "sp|Q6KC79|NIPBL_HUMAN,tr|A0A590UJS4|A0A590UJS4_HUMAN" 2 891.4814 0.73 16874 17349 2 891.482053 446.748 Nipped-B-like protein OS=Homo sapiens OX=9606 GN=NIPBL PE=1 SV=2 5.84 3187.5 - 877740 - - - 0.7134 - 1.685 0.291 - 258.7 1 2 0 0.0006 7 0 0 0 1.50E+07 2.06E+07 - - - 2.8434 0.9998 221125_WJC_METTL3_EV_vs_WT_F02.17352.17352.2 0.000245 26-Oct K.LIGVPADAEALSER.S sp|Q96EA4|SPDLY_HUMAN 1 1439.762 0.11 16877 17352 2 1439.762022 720.8883 Protein Spindly OS=Homo sapiens OX=9606 GN=SPDL1 PE=1 SV=2 4.14 3187.9 - 245985 - - - 0.009 - 2.09 0.449 - 204.8 1 2 0 0 14 0 0 0 6.42E+06 6.04E+07 - - - 4.2072 0.9997 221125_WJC_METTL3_EV_vs_WT_F02.17356.17356.2 9.77E-05 20-Oct K.WEGLVYAPPGK[136.11].E "sp|Q9Y2W1|TR150_HUMAN,tr|A0A3B3ITZ9|A0A3B3ITZ9_HUMAN" 2 1223.643 2.79 16880 17356 2 1223.644956 612.8288 Thyroid hormone receptor-associated protein 3 OS=Homo sapiens OX=9606 GN=THRAP3 PE=1 SV=2 6 3188.4 - 5.67E+06 - - - 1.5912 - 2.003 0.464 - 274.9 1 2 0 0.0019 11 0 0 0 1.48E+10 5.30E+09 - - - 4.3467 0.9987 221125_WJC_METTL3_EV_vs_WT_F02.17358.17358.2 0.0408 14-Jun K.EAFGFIER.G "sp|O75534|CSDE1_HUMAN,tr|E9PLT0|E9PLT0_HUMAN,tr|E9PNG3|E9PNG3_HUMAN" 3 967.4763 0.58 16881 17358 2 967.476643 484.7454 Cold shock domain-containing protein E1 OS=Homo sapiens OX=9606 GN=CSDE1 PE=1 SV=2 4.53 3188.6 - 2.07E+06 - - - 0.3225 - 1.329 0.308 - 134.5 1 2 0 0.0003 8 0 0 0 3.79E+07 6.56E+07 - - - 2.1736 0.9994 221125_WJC_METTL3_EV_vs_WT_F02.17359.17359.2 2.30E-05 24-Dec R.ALIGDDVGLTSYK.H sp|Q53F19|NCBP3_HUMAN 1 1350.7031 1.32 16882 17359 2 1350.707057 676.3588 Nuclear cap-binding protein subunit 3 OS=Homo sapiens OX=9606 GN=NCBP3 PE=1 SV=2 4.21 3188.7 - 1.39E+06 - - - 2.9318 - 2.676 0.432 - 430.9 1 2 0 0.004 13 0 0 0 4.74E+07 3.59E+07 - - - 4.7568 0.9993 221125_WJC_METTL3_EV_vs_WT_F02.17361.17361.2 0.139 14-Aug K.NLQLLMDR.V "sp|O15372|EIF3H_HUMAN,tr|B3KS98|B3KS98_HUMAN,tr|A0A087WZK9|A0A087WZK9_HUMAN,tr|E5RJT0|E5RJT0_HUMAN" 4 1001.5328 2.69 16884 17361 2 1001.53242 501.7737 Eukaryotic translation initiation factor 3 subunit H OS=Homo sapiens OX=9606 GN=EIF3H PE=1 SV=1 5.84 3188.8 - 787745 - - - -0.3804 - 1.756 0.271 - 240 1 2 0 -0.0004 8 0 0 0 1.64E+08 6.08E+07 - - - 2.7406 0.9663 221125_WJC_METTL3_EV_vs_WT_F02.17363.17363.2 1.27E-05 24-Dec R.ALSAVHSPTFC[160.03]QL.A "sp|Q8IY67|RAVR1_HUMAN,tr|E9PAU2|E9PAU2_HUMAN,tr|A0A087WZ13|A0A087WZ13_HUMAN" 3 1429.7024 - 16886 17363 2 1429.704902 715.8585 Ribonucleoprotein PTB-binding 1 OS=Homo sapiens OX=9606 GN=RAVER1 PE=1 SV=1 6.78 3189.1 - 611213 - - - 1.7605 - 2.012 0.376 - 309.8 1 1 0 0.0025 13 0 0 0 - - - - - 3.6117 0.8944 221125_WJC_METTL3_EV_vs_WT_F02.17368.17368.2 0.00133 16-Jun R.YC[160.03]VQLSQIQ.G "sp|Q04695|K1C17_HUMAN,sp|P13645|K1C10_HUMAN,tr|A0A1B0GVI3|A0A1B0GVI3_HUMAN,tr|F5GWP8|F5GWP8_HUMAN" 4 1137.5488 - 16889 17368 2 1137.547977 569.7817 "Keratin, type I cytoskeletal 17 OS=Homo sapiens OX=9606 GN=KRT17 PE=1 SV=2" 5.52 3189.7 - 8.86E+06 - - - -0.763 - 1.41 0.25 - 120.9 1 1 0 -0.0009 9 0 0 0 - - - - - 1.8813 0.9995 221125_WJC_METTL3_EV_vs_WT_F02.17370.17370.2 0.000214 26-Jun K.ELSDPAGAIIYTSR[166.11].F "sp|O15067|PUR4_HUMAN,tr|J3KT98|J3KT98_HUMAN" 2 1501.7652 0.71 16891 17370 2 1501.764161 751.8899 Phosphoribosylformylglycinamidine synthase OS=Homo sapiens OX=9606 GN=PFAS PE=1 SV=4 4.37 3189.9 - 378922 - - - -0.6872 - 1.524 0.417 - 47.8 1 2 0 -0.001 14 0 0 0 5.97E+06 8.44E+06 - - - 3.178 0.9997 221125_WJC_METTL3_EV_vs_WT_F02.17375.17375.2 3.94E-05 24-Dec R.ALIGDDVGLTSYK[136.11].H sp|Q53F19|NCBP3_HUMAN 1 1358.7173 1.32 16894 17375 2 1358.720265 680.3659 Nuclear cap-binding protein subunit 3 OS=Homo sapiens OX=9606 GN=NCBP3 PE=1 SV=2 4.21 3190.6 - 2.53E+06 - - - 2.1844 - 2.559 0.497 - 466.7 1 2 0 0.003 13 0 0 0 4.74E+07 3.59E+07 - - - 5.1225 0.9986 221125_WJC_METTL3_EV_vs_WT_F02.17376.17376.2 3.38E-05 22-Nov K.LVFLEDGTSQVR.K "sp|Q8IWC1|MA7D3_HUMAN,tr|A0A0A0MRP0|A0A0A0MRP0_HUMAN" 2 1362.7143 1.26 16895 17376 2 1362.720218 682.3644 MAP7 domain-containing protein 3 OS=Homo sapiens OX=9606 GN=MAP7D3 PE=1 SV=2 4.37 3190.7 - 2.02E+06 - - - 4.3208 - 2.203 0.522 - 468.9 1 2 0 0.0059 12 0 0 0 7.06E+07 5.58E+07 - - - 4.9728 0.9931 221125_WJC_METTL3_EV_vs_WT_F02.17382.17382.2 1.80E-06 24-Nov M.ELPYGTLTDDEMR.R sp|Q86U44|MTA70_HUMAN 1 1538.6923 0.02 16901 17382 2 1538.690757 770.3534 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 3.92 3191.2 - 340023 - - - -0.9859 - 1.918 0.618 - 354.2 1 1 0 -0.0015 13 0 0 0 6.86E+06 4.37E+08 - - - 5.2766 0.8896 221125_WJC_METTL3_EV_vs_WT_F02.17387.17387.2 0.0192 14-Sep H.SLIPSYIR[166.11].D "sp|Q5JT25|RAB41_HUMAN,sp|P20340|RAB6A_HUMAN,sp|Q9NRW1|RAB6B_HUMAN,tr|J3KR73|J3KR73_HUMAN,tr|C9JU14|C9JU14_HUMAN" 5 957.5523 1.31 16904 17387 2 957.549977 479.7834 Ras-related protein Rab-41 OS=Homo sapiens OX=9606 GN=RAB41 PE=1 SV=2 8.46 3191.8 - 1.70E+06 - - - -2.4124 - 1.576 0.307 - 282.5 1 1 0 -0.0023 8 0 0 0 4.56E+07 3.48E+07 - - - 2.6797 0.9984 221125_WJC_METTL3_EV_vs_WT_F02.17389.17389.2 0.0858 12-Jun K.HDELTYF.- "sp|P04080|CYTB_HUMAN,tr|A0A1W2PQG6|A0A1W2PQG6_HUMAN" 2 923.4025 - 16906 17389 2 923.402583 462.7085 Cystatin-B OS=Homo sapiens OX=9606 GN=CSTB PE=1 SV=2 4.35 3191.9 - 2.66E+06 - - - 0.0921 - 1.077 0.365 - 152.6 1 2 0 0.0001 7 0 0 0 - - - - - 1.9719 0.9975 221125_WJC_METTL3_EV_vs_WT_F02.17390.17390.2 0.786 16-Sep R.LLLPGELAK.H "sp|Q8N257|H2B3B_HUMAN,sp|A0A2R8Y619|H2BE1_HUMAN,sp|P33778|H2B1B_HUMAN,sp|Q96A08|H2B1A_HUMAN,sp|Q5QNW6|H2B2F_HUMAN,sp|P58876|H2B1D_HUMAN,sp|Q99880|H2B1L_HUMAN,sp|P62807|H2B1C_HUMAN,sp|Q99877|H2B1N_HUMAN,sp|P57053|H2BFS_HUMAN,sp|P23527|H2B1O_HUMAN,sp|O60814|H2B1K_HUMAN,sp|Q93079|H2B1H_HUMAN,sp|Q99879|H2B1M_HUMAN,sp|Q16778|H2B2E_HUMAN,sp|P06899|H2B1J_HUMAN,tr|U3KQK0|U3KQK0_HUMAN" 17 952.5957 1.1 16907 17390 2 952.595608 477.3051 Histone H2B type 3-B OS=Homo sapiens OX=9606 GN=H2BU1 PE=1 SV=3 6 3192 - 1.46E+06 - - - -0.1155 - 1.542 0.178 - 231.1 1 2 0 -0.0001 9 0 0 0 9.41E+07 8.59E+07 - - - 1.6086 0.9989 221125_WJC_METTL3_EV_vs_WT_F02.17393.17393.2 0.0501 14-Jul K.SALAFLNR[166.11].G "sp|Q9H0H5|RGAP1_HUMAN,tr|F8VQZ5|F8VQZ5_HUMAN,tr|F8VV47|F8VV47_HUMAN,tr|F8W1T4|F8W1T4_HUMAN,tr|F8VWY4|F8VWY4_HUMAN,tr|F8VV37|F8VV37_HUMAN,tr|F8VRD2|F8VRD2_HUMAN,tr|F8VZ66|F8VZ66_HUMAN,tr|F8VWX0|F8VWX0_HUMAN,tr|F8VQF5|F8VQF5_HUMAN,tr|F8W1E5|F8W1E5_HUMAN,tr|F8W0L1|F8W0L1_HUMAN,tr|F8VYH6|F8VYH6_HUMAN,tr|F8VVE5|F8VVE5_HUMAN" 14 900.5057 1.4 16910 17393 2 900.506152 451.2601 Rac GTPase-activating protein 1 OS=Homo sapiens OX=9606 GN=RACGAP1 PE=1 SV=1 9.47 3192.3 - 676918 - - - 0.5341 - 1.639 0.25 - 166.9 1 2 0 0.0005 8 0 0 0 2.15E+07 1.53E+07 - - - 2.3775 0.9997 221125_WJC_METTL3_EV_vs_WT_F02.17394.17394.2 8.82E-05 16-Sep K.EAEEEFWYR.Q "sp|Q9Y6M9|NDUB9_HUMAN,tr|A0A7I2V620|A0A7I2V620_HUMAN,tr|A0A3B3IT57|A0A3B3IT57_HUMAN,tr|E7EWZ0|E7EWZ0_HUMAN,tr|E9PF49|E9PF49_HUMAN,tr|E9PH64|E9PH64_HUMAN" 6 1257.5302 1.7 16911 17394 2 1257.527962 629.7724 NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 9 OS=Homo sapiens OX=9606 GN=NDUFB9 PE=1 SV=3 4.09 3192.4 - 630100 - - - -1.794 - 2.01 0.487 - 523.4 1 2 0 -0.0023 9 0 0 0 2.87E+07 1.69E+07 - - - 4.657 0.9999 221125_WJC_METTL3_EV_vs_WT_F02.17395.17395.2 1.68E-05 24-Dec K.LLASANLEEVTMK.Q "sp|P35659|DEK_HUMAN,tr|H0Y993|H0Y993_HUMAN,tr|A0A494C028|A0A494C028_HUMAN,tr|A0A494C198|A0A494C198_HUMAN,tr|B4DFG0|B4DFG0_HUMAN" 5 1417.7487 0.77 16912 17395 2 1417.749924 709.8816 Protein DEK OS=Homo sapiens OX=9606 GN=DEK PE=1 SV=1 4.53 3192.6 - 536179 - - - 0.8866 - 2.615 0.506 - 366.2 1 2 0 0.0013 13 0 0 0 6.66E+07 8.61E+07 - - - 5.245 1 221125_WJC_METTL3_EV_vs_WT_F02.17396.17396.2 1.42E-06 15/28 K.VLASTISTTSTIEFK[136.11].N sp|Q5VT52|RPRD2_HUMAN 1 1604.8753 1.66 16913 17396 2 1604.876258 803.4449 Regulation of nuclear pre-mRNA domain-containing protein 2 OS=Homo sapiens OX=9606 GN=RPRD2 PE=1 SV=1 5.97 3192.7 - 274197 - - - 0.6256 - 3.018 0.542 - 413 1 2 0 0.001 15 0 0 0 8.40E+06 5.05E+06 - - - 5.7596 0.999 221125_WJC_METTL3_EV_vs_WT_F02.17398.17398.2 0.0492 14-Jul R.EFADFEYR[166.11].K "sp|Q8ND56|LS14A_HUMAN,tr|A0A140TA66|A0A140TA66_HUMAN,tr|A0A096LP11|A0A096LP11_HUMAN,tr|A0A0G2JQ95|A0A0G2JQ95_HUMAN" 4 1085.4693 1.35 16914 17398 2 1085.470513 543.7419 Protein LSM14 homolog A OS=Homo sapiens OX=9606 GN=LSM14A PE=1 SV=3 4.14 3192.9 - 764227 - - - 1.076 - 1.303 0.385 - 192.6 1 2 0 0.0012 8 0 0 0 6.25E+06 4.61E+06 - - - 2.6825 0.9963 221125_WJC_METTL3_EV_vs_WT_F02.17400.17400.2 0.0742 14-Sep R.LLGWIQNK[136.11].L "sp|O75369|FLNB_HUMAN,sp|Q14315|FLNC_HUMAN,sp|P21333|FLNA_HUMAN,tr|A0A7P0NMY4|A0A7P0NMY4_HUMAN,tr|Q60FE5|Q60FE5_HUMAN,tr|A0A7I2V3E6|A0A7I2V3E6_HUMAN,tr|A0A804HK76|A0A804HK76_HUMAN,tr|A0A804HJC2|A0A804HJC2_HUMAN,tr|A0A087WWY3|A0A087WWY3_HUMAN,tr|A0A804HL72|A0A804HL72_HUMAN,tr|F8WE98|F8WE98_HUMAN" 11 978.5742 1.11 16915 17400 2 978.575929 490.2944 Filamin-B OS=Homo sapiens OX=9606 GN=FLNB PE=1 SV=2 8.75 3193.1 - 2.52E+06 - - - 1.7648 - 1.31 0.272 - 171.2 1 2 0 0.0017 8 0 0 0 5.14E+07 4.62E+07 - - - 1.8638 0.9971 221125_WJC_METTL3_EV_vs_WT_F02.17401.17401.2 0.111 14-Aug R.LLGWIQNK.L "sp|O75369|FLNB_HUMAN,sp|Q14315|FLNC_HUMAN,sp|P21333|FLNA_HUMAN,tr|A0A7P0NMY4|A0A7P0NMY4_HUMAN,tr|Q60FE5|Q60FE5_HUMAN,tr|A0A7I2V3E6|A0A7I2V3E6_HUMAN,tr|A0A804HK76|A0A804HK76_HUMAN,tr|A0A804HJC2|A0A804HJC2_HUMAN,tr|A0A087WWY3|A0A087WWY3_HUMAN,tr|A0A804HL72|A0A804HL72_HUMAN,tr|F8WE98|F8WE98_HUMAN" 11 970.56 1.11 16916 17401 2 970.5598 486.2873 Filamin-B OS=Homo sapiens OX=9606 GN=FLNB PE=1 SV=2 8.75 3193.2 - 1.75E+06 - - - -0.2081 - 1.29 0.228 - 149.6 1 2 0 -0.0002 8 0 0 0 5.15E+07 4.62E+07 - - - 1.4929 0.9999 221125_WJC_METTL3_EV_vs_WT_F02.17402.17402.2 1.83E-05 13/24 K.LLASANLEEVTMK[136.11].Q "sp|P35659|DEK_HUMAN,tr|H0Y993|H0Y993_HUMAN,tr|A0A494C028|A0A494C028_HUMAN,tr|A0A494C198|A0A494C198_HUMAN,tr|B4DFG0|B4DFG0_HUMAN" 5 1425.7629 0.77 16917 17402 2 1425.764655 713.8887 Protein DEK OS=Homo sapiens OX=9606 GN=DEK PE=1 SV=1 4.53 3193.3 - 1.77E+06 - - - 1.2541 - 2.771 0.541 - 442.8 1 2 0 0.0018 13 0 0 0 6.66E+07 8.61E+07 - - - 5.6521 0.9999 221125_WJC_METTL3_EV_vs_WT_F02.17403.17403.2 0.000125 14/28 K.VLASTISTTSTIEFK.N sp|Q5VT52|RPRD2_HUMAN 1 1596.8611 1.66 16918 17403 2 1596.861274 799.4378 Regulation of nuclear pre-mRNA domain-containing protein 2 OS=Homo sapiens OX=9606 GN=RPRD2 PE=1 SV=1 5.97 3193.5 - 470123 - - - 0.1378 - 2.061 0.504 - 265.7 1 2 0 0.0002 15 0 0 0 8.40E+06 5.05E+06 - - - 4.5415 0.9983 221125_WJC_METTL3_EV_vs_WT_F02.17404.17404.3 0.02 Oct-36 R.LFHSLMVLEK[136.11].L sp|Q16706|MA2A1_HUMAN 1 1223.6828 2.31 16919 17404 3 1223.683949 408.9015 Alpha-mannosidase 2 OS=Homo sapiens OX=9606 GN=MAN2A1 PE=1 SV=2 6.75 3193.6 - 356135 - - - 0.9668 - 1.769 0.25 - 106 1 2 0 0.0012 10 0 0 0 1.48E+07 6.44E+06 - - - 2.9928 0.9998 221125_WJC_METTL3_EV_vs_WT_F02.17409.17409.2 7.63E-07 24-Dec R.IGNLQTDLSDGLR[166.11].L "sp|O75369|FLNB_HUMAN,tr|A0A804HK76|A0A804HK76_HUMAN,tr|A0A804HJC2|A0A804HJC2_HUMAN,tr|A0A804HL72|A0A804HL72_HUMAN" 4 1410.7342 1.25 16922 17409 2 1410.736566 706.3744 Filamin-B OS=Homo sapiens OX=9606 GN=FLNB PE=1 SV=2 4.21 3194.3 - 836607 - - - 1.658 - 2.838 0.518 - 555.3 1 2 0 0.0023 13 0 0 0 1.53E+07 1.22E+07 - - - 5.5434 0.9978 221125_WJC_METTL3_EV_vs_WT_F02.17410.17410.2 0.731 16-Jul K.SQLLSYIDR.L sp|P33993|MCM7_HUMAN 1 1093.5768 0.73 16923 17410 2 1093.578002 547.7957 DNA replication licensing factor MCM7 OS=Homo sapiens OX=9606 GN=MCM7 PE=1 SV=4 5.55 3194.3 - 1.30E+06 - - - 1.1229 - 1.663 0.198 - 228.8 1 2 0 0.0012 9 0 0 0 5.14E+07 6.99E+07 - - - 1.9745 0.9999 221125_WJC_METTL3_EV_vs_WT_F02.17412.17412.2 0.00013 24-Dec R.IGNLQTDLSDGLR.L "sp|O75369|FLNB_HUMAN,tr|A0A804HK76|A0A804HK76_HUMAN,tr|A0A804HJC2|A0A804HJC2_HUMAN,tr|A0A804HL72|A0A804HL72_HUMAN" 4 1400.726 1.34 16925 17412 2 1400.727007 701.3703 Filamin-B OS=Homo sapiens OX=9606 GN=FLNB PE=1 SV=2 4.21 3194.5 - 696694 - - - 0.7496 - 2.844 0.466 - 585 1 2 0 0.001 13 0 0 0 1.67E+07 1.25E+07 - - - 5.1651 0.8186 221125_WJC_METTL3_EV_vs_WT_F02.17416.17416.3 0.000546 Sep-48 M.ELPYGTLTDDEMR[166.11].R sp|Q86U44|MTA70_HUMAN 1 1548.7005 0.01 16929 17416 3 1548.694421 517.2408 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 3.92 3195 - 454132 - - - -3.9536 - 2.008 0.346 - 75.8 1 1 0 -0.0061 13 0 0 0 8.86E+04 1.59E+07 - - - 4.286 0.9998 221125_WJC_METTL3_EV_vs_WT_F02.17417.17417.2 6.72E-06 22-Oct K.VPEESVLPLVQK.S "sp|Q9UKV3|ACINU_HUMAN,tr|S4R3H4|S4R3H4_HUMAN,tr|E7EQT4|E7EQT4_HUMAN" 3 1336.7602 1.37 16930 17417 2 1336.757909 669.3874 Apoptotic chromatin condensation inducer in the nucleus OS=Homo sapiens OX=9606 GN=ACIN1 PE=1 SV=2 4.53 3195.1 - 275225 - - - -1.7273 - 2.072 0.526 - 261.9 1 2 0 -0.0023 12 0 0 0 6.41E+06 4.67E+06 - - - 4.8422 0.976 221125_WJC_METTL3_EV_vs_WT_F02.17422.17422.2 0.377 14-Sep K.SALAFLNR.G "sp|Q9H0H5|RGAP1_HUMAN,tr|F8VQZ5|F8VQZ5_HUMAN,tr|F8VV47|F8VV47_HUMAN,tr|F8W1T4|F8W1T4_HUMAN,tr|F8VWY4|F8VWY4_HUMAN,tr|F8VV37|F8VV37_HUMAN,tr|F8VRD2|F8VRD2_HUMAN,tr|F8VZ66|F8VZ66_HUMAN,tr|F8VWX0|F8VWX0_HUMAN,tr|F8VQF5|F8VQF5_HUMAN,tr|F8W1E5|F8W1E5_HUMAN,tr|F8W0L1|F8W0L1_HUMAN,tr|F8VYH6|F8VYH6_HUMAN,tr|F8VVE5|F8VVE5_HUMAN" 14 890.4974 1.42 16933 17422 2 890.502354 446.256 Rac GTPase-activating protein 1 OS=Homo sapiens OX=9606 GN=RACGAP1 PE=1 SV=1 9.47 3195.6 - 1.54E+06 - - - 5.5621 - 1.953 0.199 - 293.6 1 2 0 0.005 8 0 0 0 2.17E+07 1.53E+07 - - - 2.528 0.9997 221125_WJC_METTL3_EV_vs_WT_F02.17424.17424.2 5.84E-05 16-Aug K.EAEEEFWYR[166.11].Q "sp|Q9Y6M9|NDUB9_HUMAN,tr|A0A7I2V620|A0A7I2V620_HUMAN,tr|A0A3B3IT57|A0A3B3IT57_HUMAN,tr|E7EWZ0|E7EWZ0_HUMAN,tr|E9PF49|E9PF49_HUMAN,tr|E9PH64|E9PH64_HUMAN" 6 1267.5385 1.71 16935 17424 2 1267.539096 634.7765 NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 9 OS=Homo sapiens OX=9606 GN=NDUFB9 PE=1 SV=3 4.09 3195.8 - 1.01E+06 - - - 0.4797 - 1.678 0.435 - 263.6 1 2 0 0.0006 9 0 0 0 2.87E+07 1.67E+07 - - - 3.7512 0.9998 221125_WJC_METTL3_EV_vs_WT_F02.17425.17425.2 0.000165 24-Dec K.LC[160.03]SLFYTNEEVAK.N "sp|P43243|MATR3_HUMAN,tr|B3KM87|B3KM87_HUMAN,tr|A8MXP9|A8MXP9_HUMAN,tr|A0A0R4J2E8|A0A0R4J2E8_HUMAN" 4 1572.7494 1.26 16936 17425 2 1572.745704 787.382 Matrin-3 OS=Homo sapiens OX=9606 GN=MATR3 PE=1 SV=2 4.53 3195.9 - 1.00E+06 - - - -2.3468 - 2.663 0.548 - 703 1 2 0 -0.0037 13 0 0 0 6.90E+08 5.47E+08 - - - 5.6012 0.9998 221125_WJC_METTL3_EV_vs_WT_F02.17426.17426.2 1.59E-05 14/22 K.IIAELNETWEEK.L "sp|O43896|KIF1C_HUMAN,sp|O60333|KIF1B_HUMAN,sp|Q12756|KIF1A_HUMAN,tr|A0A3B3ITW6|A0A3B3ITW6_HUMAN,tr|A0A3B3ITF7|A0A3B3ITF7_HUMAN,tr|A0A3B3ITE5|A0A3B3ITE5_HUMAN,tr|A0A3B3IUA1|A0A3B3IUA1_HUMAN,tr|A0A3B3IT28|A0A3B3IT28_HUMAN,tr|A0A087WWA3|A0A087WWA3_HUMAN,tr|A0A3F2YNW9|A0A3F2YNW9_HUMAN,tr|A0A6Q8PGE4|A0A6Q8PGE4_HUMAN,tr|A0A3B3IU40|A0A3B3IU40_HUMAN,tr|Q4R9M9|Q4R9M9_HUMAN,tr|A0A3B3ITK3|A0A3B3ITK3_HUMAN" 14 1473.7351 0.91 16937 17426 2 1473.736643 737.8748 Kinesin-like protein KIF1C OS=Homo sapiens OX=9606 GN=KIF1C PE=1 SV=3 4.09 3196.1 - 633901 - - - 1.03 - 2.592 0.457 - 562.7 1 2 0 0.0015 12 0 0 0 1.71E+07 1.87E+07 - - - 4.9219 0.9997 221125_WJC_METTL3_EV_vs_WT_F02.17427.17427.2 0.000118 28-Sep K.NLLTGETEADPEMIK.R "sp|O96005|CLPT1_HUMAN,tr|K7EQQ1|K7EQQ1_HUMAN" 2 1659.8026 1.37 16938 17427 2 1659.803974 830.9086 Cleft lip and palate transmembrane protein 1 OS=Homo sapiens OX=9606 GN=CLPTM1 PE=1 SV=1 4 3196.2 - 266390 - - - 0.8561 - 2.05 0.42 - 175.4 1 2 0 0.0014 15 0 0 0 3.52E+06 2.57E+06 - - - 3.9075 1 221125_WJC_METTL3_EV_vs_WT_F02.17428.17428.2 2.13E-07 28-Nov K.NLLTGETEADPEMIK[136.11].R "sp|O96005|CLPT1_HUMAN,tr|K7EQQ1|K7EQQ1_HUMAN" 2 1667.8168 1.37 16939 17428 2 1667.81693 834.9157 Cleft lip and palate transmembrane protein 1 OS=Homo sapiens OX=9606 GN=CLPTM1 PE=1 SV=1 4 3196.3 - 233197 - - - 0.1061 - 2.445 0.626 - 295.4 1 2 0 0.0002 15 0 0 0 3.52E+06 2.57E+06 - - - 5.8626 0.9999 221125_WJC_METTL3_EV_vs_WT_F02.17430.17430.2 2.52E-06 26-Oct K.LIGVPADAEALSER[166.11].S sp|Q96EA4|SPDLY_HUMAN 1 1449.7703 0.11 16940 17430 2 1449.770079 725.8924 Protein Spindly OS=Homo sapiens OX=9606 GN=SPDL1 PE=1 SV=2 4.14 3196.5 - 547406 - - - -0.138 - 1.998 0.518 - 238.4 1 2 0 -0.0002 14 0 0 0 6.42E+06 5.61E+07 - - - 4.6038 1 221125_WJC_METTL3_EV_vs_WT_F02.17432.17432.2 1.92E-05 24-Dec K.LC[160.03]SLFYTNEEVAK[136.11].N "sp|P43243|MATR3_HUMAN,tr|B3KM87|B3KM87_HUMAN,tr|A8MXP9|A8MXP9_HUMAN,tr|A0A0R4J2E8|A0A0R4J2E8_HUMAN" 4 1580.7636 1.26 16941 17432 2 1580.762332 791.3891 Matrin-3 OS=Homo sapiens OX=9606 GN=MATR3 PE=1 SV=2 4.53 3196.8 - 1.92E+06 - - - -0.799 - 2.704 0.607 - 592 1 2 0 -0.0013 13 0 0 0 6.90E+08 5.47E+08 - - - 6.0769 0.9643 221125_WJC_METTL3_EV_vs_WT_F02.17435.17435.2 0.00358 14-Aug K.GIAYIEFK[136.11].T "sp|P19338|NUCL_HUMAN,tr|A0A7I2V506|A0A7I2V506_HUMAN,tr|A0A7I2V2U7|A0A7I2V2U7_HUMAN,tr|A0A7I2V3F3|A0A7I2V3F3_HUMAN,tr|A0A7I2V428|A0A7I2V428_HUMAN,tr|A0A7I2V349|A0A7I2V349_HUMAN,tr|H7BY16|H7BY16_HUMAN,tr|A0A7I2V5M5|A0A7I2V5M5_HUMAN,tr|C9JLB1|C9JLB1_HUMAN" 9 947.5208 0.98 16944 17435 2 947.515144 474.7677 Nucleolin OS=Homo sapiens OX=9606 GN=NCL PE=1 SV=3 6 3197 - 1.12E+06 - - - -5.9365 - 1.44 0.303 - 200.4 1 2 0 -0.0056 8 0 0 0 9.48E+07 9.64E+07 - - - 2.3769 0.9982 221125_WJC_METTL3_EV_vs_WT_F02.17436.17436.2 0.0238 16-Aug K.FQIEANFPR[166.11].R sp|Q96CS3|FAF2_HUMAN 1 1130.5748 1.01 16945 17436 2 1130.575251 566.2947 FAS-associated factor 2 OS=Homo sapiens OX=9606 GN=FAF2 PE=1 SV=2 6 3197.1 - 914162 - - - 0.3874 - 1.469 0.24 - 179 1 2 0 0.0004 9 0 0 0 3.67E+07 3.63E+07 - - - 1.9261 0.9032 221125_WJC_METTL3_EV_vs_WT_F02.17437.17437.2 0.024 14-Jun R.VVHIMDFQ.R "sp|P43243|MATR3_HUMAN,tr|D6RE02|D6RE02_HUMAN,tr|B3KM87|B3KM87_HUMAN,tr|A8MXP9|A8MXP9_HUMAN,tr|D6RAY2|D6RAY2_HUMAN,tr|D6R991|D6R991_HUMAN,tr|A0A0R4J2E8|A0A0R4J2E8_HUMAN,tr|D6RAM9|D6RAM9_HUMAN,tr|D6RIA2|D6RIA2_HUMAN,tr|H0Y8T4|H0Y8T4_HUMAN,tr|D6REM6|D6REM6_HUMAN,tr|D6RBI2|D6RBI2_HUMAN" 12 987.4848 - 16946 17437 2 987.482973 494.7497 Matrin-3 OS=Homo sapiens OX=9606 GN=MATR3 PE=1 SV=2 5.08 3197.2 - 577496 - - - -1.838 - 1.32 0.347 - 139 1 1 0 -0.0018 8 0 0 0 - - - - - 2.4407 0.9997 221125_WJC_METTL3_EV_vs_WT_F02.17439.17439.2 1.17 26-Sep R.LVVLATPQVSDSMR.K "sp|P46976|GLYG_HUMAN,tr|G5E9W8|G5E9W8_HUMAN,tr|C9JQ42|C9JQ42_HUMAN" 3 1514.8127 1.32 16948 17439 2 1514.811528 758.4136 Glycogenin-1 OS=Homo sapiens OX=9606 GN=GYG1 PE=1 SV=4 5.84 3197.5 - 258822 - - - -0.7499 - 2.027 0.381 - 224.5 1 2 0 -0.0011 14 0 0 0 6.93E+06 5.24E+06 - - - 3.6278 0.9999 221125_WJC_METTL3_EV_vs_WT_F02.17442.17442.2 0.00169 20-Dec K.GPLQSVQVFGR.K "sp|P62249|RS16_HUMAN,tr|M0R210|M0R210_HUMAN,tr|M0R3H0|M0R3H0_HUMAN,tr|Q6IPX4|Q6IPX4_HUMAN" 4 1186.6459 0.55 16950 17442 2 1186.646889 594.3302 40S ribosomal protein S16 OS=Homo sapiens OX=9606 GN=RPS16 PE=1 SV=2 9.75 3197.8 - 4.89E+07 - - - 0.8705 - 2.62 0.514 - 623.3 1 2 0 0.001 11 0 0 0 1.79E+09 3.28E+09 - - - 5.4427 0.9949 221125_WJC_METTL3_EV_vs_WT_F02.17446.17446.2 7.56E-07 24-Sep M.ELPYGTLTDDEMR[166.11].R sp|Q86U44|MTA70_HUMAN 1 1548.7005 0.02 16953 17446 2 1548.700447 775.3575 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 3.92 3198.1 - 9.88E+06 - - - -0.0626 - 2.085 0.627 - 226.5 1 1 0 -0.0001 13 0 0 0 6.86E+06 4.37E+08 - - - 5.5578 0.9999 221125_WJC_METTL3_EV_vs_WT_F02.17448.17448.2 4.42E-05 22-Dec K.IIAELNETWEEK[136.11].L "sp|O43896|KIF1C_HUMAN,sp|O60333|KIF1B_HUMAN,sp|Q12756|KIF1A_HUMAN,tr|A0A3B3ITW6|A0A3B3ITW6_HUMAN,tr|A0A3B3ITF7|A0A3B3ITF7_HUMAN,tr|A0A3B3ITE5|A0A3B3ITE5_HUMAN,tr|A0A3B3IUA1|A0A3B3IUA1_HUMAN,tr|A0A3B3IT28|A0A3B3IT28_HUMAN,tr|A0A087WWA3|A0A087WWA3_HUMAN,tr|A0A3F2YNW9|A0A3F2YNW9_HUMAN,tr|A0A6Q8PGE4|A0A6Q8PGE4_HUMAN,tr|A0A3B3IU40|A0A3B3IU40_HUMAN,tr|Q4R9M9|Q4R9M9_HUMAN,tr|A0A3B3ITK3|A0A3B3ITK3_HUMAN" 14 1481.7493 0.92 16955 17448 2 1481.749052 741.8819 Kinesin-like protein KIF1C OS=Homo sapiens OX=9606 GN=KIF1C PE=1 SV=3 4.09 3198.3 - 934342 - - - -0.1842 - 2.657 0.494 - 363.7 1 2 0 -0.0003 12 0 0 0 1.71E+07 1.87E+07 - - - 5.2608 0.9992 221125_WJC_METTL3_EV_vs_WT_F02.17450.17450.3 0.0153 Aug-40 K.GPLQSVQVFGR.K "sp|P62249|RS16_HUMAN,tr|M0R210|M0R210_HUMAN,tr|M0R3H0|M0R3H0_HUMAN,tr|Q6IPX4|Q6IPX4_HUMAN" 4 1186.6459 0.26 16957 17450 3 1186.645956 396.5559 40S ribosomal protein S16 OS=Homo sapiens OX=9606 GN=RPS16 PE=1 SV=2 9.75 3198.5 - 425436 - - - 0.0843 - 1.797 0.29 - 98.6 1 2 0 0.0001 11 0 0 0 1.08E+07 4.14E+07 - - - 3.4382 0.997 221125_WJC_METTL3_EV_vs_WT_F02.17455.17455.2 2.26E-07 22-Nov R.IMNTFSVMPSPK[136.11].V "sp|Q9BVA1|TBB2B_HUMAN,sp|Q13885|TBB2A_HUMAN,sp|Q9BUF5|TBB6_HUMAN,tr|K7ESM5|K7ESM5_HUMAN,tr|K7ES63|K7ES63_HUMAN" 5 1358.6818 0.72 16960 17455 2 1358.674029 680.3482 Tubulin beta-2B chain OS=Homo sapiens OX=9606 GN=TUBB2B PE=1 SV=1 8.75 3199.2 - 796496 - - - -5.7048 - 2.29 0.56 - 414.9 1 2 0 -0.0078 12 0 0 0 2.15E+07 2.99E+07 - - - 5.3548 0.9994 221125_WJC_METTL3_EV_vs_WT_F02.17456.17456.2 0.00434 16-Aug K.LQEVDSLWK.E "sp|Q9Y2X3|NOP58_HUMAN,tr|F8WED0|F8WED0_HUMAN" 2 1116.5815 2.97 16961 17456 2 1116.582825 559.298 Nucleolar protein 58 OS=Homo sapiens OX=9606 GN=NOP58 PE=1 SV=1 4.37 3199.3 - 1.99E+06 - - - 1.1643 - 1.702 0.363 - 154.7 1 2 0 0.0013 9 0 0 0 3.36E+07 1.13E+07 - - - 3.2602 0.9926 221125_WJC_METTL3_EV_vs_WT_F02.17457.17457.2 3.73E-05 22-Dec A.VNAVLTVADMER[166.11].R "sp|P48643|TCPE_HUMAN,tr|E9PCA1|E9PCA1_HUMAN,tr|B7ZAR1|B7ZAR1_HUMAN,tr|E7ENZ3|E7ENZ3_HUMAN" 4 1326.6841 0.5 16962 17457 2 1326.685224 664.3493 T-complex protein 1 subunit epsilon OS=Homo sapiens OX=9606 GN=CCT5 PE=1 SV=1 4.37 3199.4 - 1.20E+06 - - - 0.8427 - 2.412 0.522 - 519.3 1 1 0 0.0011 12 0 0 0 1.71E+07 3.38E+07 - - - 5.2128 0.9974 221125_WJC_METTL3_EV_vs_WT_F02.17460.17460.2 0.0271 24-Dec K.ALEFVTNPDIAAK.K sp|O75691|UTP20_HUMAN 1 1387.7347 0.97 16965 17460 2 1387.72816 694.8746 Small subunit processome component 20 homolog OS=Homo sapiens OX=9606 GN=UTP20 PE=1 SV=3 4.37 3199.8 - 342167 - - - -4.7351 - 2.315 0.426 - 503.9 1 2 0 -0.0066 13 0 0 0 3.18E+06 3.27E+06 - - - 4.3397 0.9999 221125_WJC_METTL3_EV_vs_WT_F02.17464.17464.2 1.70E-06 20-Oct K.WEGLVYAPPGK.E "sp|Q9Y2W1|TR150_HUMAN,tr|A0A3B3ITZ9|A0A3B3ITZ9_HUMAN" 2 1215.6288 3.02 16967 17464 2 1215.628376 608.8217 Thyroid hormone receptor-associated protein 3 OS=Homo sapiens OX=9606 GN=THRAP3 PE=1 SV=2 6 3200.3 - 2.45E+07 - - - -0.3562 - 1.891 0.543 - 247.2 1 2 0 -0.0004 11 0 0 0 1.66E+08 5.51E+07 - - - 4.775 0.9997 221125_WJC_METTL3_EV_vs_WT_F02.17465.17465.2 0.000133 16-Sep K.MNVFDTELK[136.11].G "sp|P16615|AT2A2_HUMAN,tr|H7C5W9|H7C5W9_HUMAN" 2 1103.5412 1.21 16968 17465 2 1103.541638 552.7779 Sarcoplasmic\endoplasmic reticulum calcium ATPase 2 OS=Homo sapiens OX=9606 GN=ATP2A2 PE=1 SV=1 4.37 3200.4 - 3.32E+06 - - - 0.3552 - 1.726 0.426 - 320.5 1 2 0 0.0004 9 0 0 0 5.48E+07 4.54E+07 - - - 3.7664 0.9989 221125_WJC_METTL3_EV_vs_WT_F02.17466.17466.2 0.0658 16-Aug R.SILEQLAEK[136.11].N "sp|P27708|PYR1_HUMAN,tr|F8VPD4|F8VPD4_HUMAN,tr|H7C3Z5|H7C3Z5_HUMAN" 3 1037.5848 0.42 16969 17466 2 1037.584712 519.7997 CAD protein OS=Homo sapiens OX=9606 GN=CAD PE=1 SV=3 4.53 3200.4 - 1.84E+06 - - - -0.1099 - 1.525 0.27 - 169.9 1 2 0 -0.0001 9 0 0 0 1.46E+07 3.50E+07 - - - 2.256 0.9998 221125_WJC_METTL3_EV_vs_WT_F02.17467.17467.2 0.000662 16-Oct R.MNVLADALK[136.11].S "sp|P62244|RS15A_HUMAN,tr|I3L246|I3L246_HUMAN,tr|I3L3P7|I3L3P7_HUMAN,tr|I3L303|I3L303_HUMAN,tr|H3BT37|H3BT37_HUMAN,tr|H3BV27|H3BV27_HUMAN,tr|H3BN98|H3BN98_HUMAN" 7 981.5409 0.8 16970 17467 2 981.541556 491.7777 40S ribosomal protein S15a OS=Homo sapiens OX=9606 GN=RPS15A PE=1 SV=2 5.59 3200.5 - 1.77E+06 - - - 0.7162 - 2.186 0.387 - 415.5 1 2 0 0.0007 9 0 0 0 4.16E+08 5.20E+08 - - - 4.1617 0.9915 221125_WJC_METTL3_EV_vs_WT_F02.17469.17469.2 5.54E-06 22-Nov A.VNAVLTVADMER.R "sp|P48643|TCPE_HUMAN,tr|E9PCA1|E9PCA1_HUMAN,tr|B7ZAR1|B7ZAR1_HUMAN,tr|E7ENZ3|E7ENZ3_HUMAN" 4 1316.6758 0.54 16972 17469 2 1316.677543 659.3452 T-complex protein 1 subunit epsilon OS=Homo sapiens OX=9606 GN=CCT5 PE=1 SV=1 4.37 3200.7 - 739814 - - - 1.2964 - 2.577 0.521 - 447.2 1 1 0 0.0017 12 0 0 0 1.95E+07 3.62E+07 - - - 5.3793 0.9998 221125_WJC_METTL3_EV_vs_WT_F02.17473.17473.2 2.48E-06 13/26 K.IAPGAVVC[160.03]VESEIR.G "sp|O00399|DCTN6_HUMAN,tr|E5RFU3|E5RFU3_HUMAN,tr|E5RK00|E5RK00_HUMAN,tr|E5RIK5|E5RIK5_HUMAN,tr|E5RGW9|E5RGW9_HUMAN" 5 1498.7814 9.45 16976 17473 2 1498.784357 750.398 Dynactin subunit 6 OS=Homo sapiens OX=9606 GN=DCTN6 PE=1 SV=1 4.53 3201.2 - 276496 - - - 1.997 - 2.476 0.558 - 560.6 1 2 0 0.003 14 0 0 0 4.06E+06 4.30E+05 - - - 5.4366 0.9998 221125_WJC_METTL3_EV_vs_WT_F02.17476.17476.2 7.41E-06 20-Sep K.EFLVAGGEDFK[136.11].L "sp|Q9Y3F4|STRAP_HUMAN,tr|H0YH33|H0YH33_HUMAN" 2 1218.6012 0.51 16977 17476 2 1218.601156 610.3079 Serine-threonine kinase receptor-associated protein OS=Homo sapiens OX=9606 GN=STRAP PE=1 SV=1 4.14 3201.6 - 3.73E+06 - - - -0.0394 - 1.99 0.481 - 321.9 1 2 0 0 11 0 0 0 4.40E+07 8.62E+07 - - - 4.4552 0.9998 221125_WJC_METTL3_EV_vs_WT_F02.17477.17477.2 0.000266 16-Oct R.MNVLADALK.S "sp|P62244|RS15A_HUMAN,tr|I3L246|I3L246_HUMAN,tr|I3L3P7|I3L3P7_HUMAN,tr|I3L303|I3L303_HUMAN,tr|H3BT37|H3BT37_HUMAN,tr|H3BV27|H3BV27_HUMAN,tr|H3BN98|H3BN98_HUMAN" 7 973.5267 0.8 16978 17477 2 973.526537 487.7706 40S ribosomal protein S15a OS=Homo sapiens OX=9606 GN=RPS15A PE=1 SV=2 5.59 3201.7 - 3.29E+06 - - - -0.1192 - 2.121 0.432 - 437.8 1 2 0 -0.0001 9 0 0 0 4.16E+08 5.20E+08 - - - 4.407 0.9996 221125_WJC_METTL3_EV_vs_WT_F02.17478.17478.2 0.00377 20-Sep R.SSGLTAVWVAR[166.11].N "sp|P53621|COPA_HUMAN,tr|A0A3B3ISC6|A0A3B3ISC6_HUMAN,tr|A0A3B3ITV3|A0A3B3ITV3_HUMAN,tr|A0A3B3IS84|A0A3B3IS84_HUMAN,tr|A0A3B3IU89|A0A3B3IU89_HUMAN,tr|A0A3B3ISK1|A0A3B3ISK1_HUMAN,tr|A0A3B3IT15|A0A3B3IT15_HUMAN" 7 1155.6276 0.07 16979 17478 2 1155.627263 578.8211 Coatomer subunit alpha OS=Homo sapiens OX=9606 GN=COPA PE=1 SV=2 9.47 3201.7 - 4.15E+06 - - - -0.2717 - 1.871 0.347 - 269 1 2 0 -0.0003 11 0 0 0 3.89E+06 5.63E+07 - - - 3.2986 0.9998 221125_WJC_METTL3_EV_vs_WT_F02.17479.17479.3 0.00021 Jul-48 K.LC[160.03]SLFYTNEEVAK.N "sp|P43243|MATR3_HUMAN,tr|B3KM87|B3KM87_HUMAN,tr|A8MXP9|A8MXP9_HUMAN,tr|A0A0R4J2E8|A0A0R4J2E8_HUMAN" 4 1572.7494 1.21 16980 17479 3 1572.75055 525.2571 Matrin-3 OS=Homo sapiens OX=9606 GN=MATR3 PE=1 SV=2 4.53 3201.8 - 2.16E+06 - - - 0.7344 - 1.624 0.442 - 48.5 1 2 0 0.0012 13 0 0 0 3.53E+07 2.93E+07 - - - 4.7822 0.9112 221125_WJC_METTL3_EV_vs_WT_F02.17481.17481.2 0.0329 16-Oct Q.ADIEAFDIR[166.11].E sp|Q9HCE5|MET14_HUMAN 1 1058.5272 0.05 16982 17481 2 1058.528959 530.2709 N6-adenosine-methyltransferase non-catalytic subunit OS=Homo sapiens OX=9606 GN=METTL14 PE=1 SV=2 4.03 3201.9 - 1.17E+06 - - - 1.6665 - 1.984 0.201 - 299.7 1 1 0 0.0018 9 0 0 0 1.66E+06 3.15E+07 - - - 2.5071 0.9999 221125_WJC_METTL3_EV_vs_WT_F02.17484.17484.2 0.000846 18-Nov K.NAAGALDLLK[136.11].E "sp|P23193|TCEA1_HUMAN,tr|A0A1W2PS15|A0A1W2PS15_HUMAN,tr|E5RFI1|E5RFI1_HUMAN,tr|B7Z4S1|B7Z4S1_HUMAN,tr|E5RJ93|E5RJ93_HUMAN,tr|A0A1W2PPZ5|A0A1W2PPZ5_HUMAN,tr|E5RK46|E5RK46_HUMAN,tr|A0A1W2PPV7|A0A1W2PPV7_HUMAN,tr|E5RIS7|E5RIS7_HUMAN" 9 992.5746 1.16 16985 17484 2 992.574595 497.2946 Transcription elongation factor A protein 1 OS=Homo sapiens OX=9606 GN=TCEA1 PE=1 SV=2 5.84 3202.3 - 598950 - - - 0 - 2.187 0.475 - 463.5 1 2 0 0 10 0 0 0 8.11E+07 6.97E+07 - - - 4.7336 0.9999 221125_WJC_METTL3_EV_vs_WT_F02.17490.17490.2 2.89E-06 18-Nov R.VGQALELPLR[166.11].L sp|Q8TEM1|PO210_HUMAN 1 1104.6531 2.19 16989 17490 2 1104.652998 553.3338 Nuclear pore membrane glycoprotein 210 OS=Homo sapiens OX=9606 GN=NUP210 PE=1 SV=3 5.97 3203 - 2.81E+06 - - - -0.0597 - 2.205 0.588 - 589 1 2 0 -0.0001 10 0 0 0 9.36E+07 4.28E+07 - - - 5.5911 0.9984 221125_WJC_METTL3_EV_vs_WT_F02.17491.17491.3 0.0414 Sep-48 K.LC[160.03]SLFYTNEEVAK[136.11].N "sp|P43243|MATR3_HUMAN,tr|B3KM87|B3KM87_HUMAN,tr|A8MXP9|A8MXP9_HUMAN,tr|A0A0R4J2E8|A0A0R4J2E8_HUMAN" 4 1580.7636 1.21 16990 17491 3 1580.763626 527.9285 Matrin-3 OS=Homo sapiens OX=9606 GN=MATR3 PE=1 SV=2 4.53 3203 - 2.17E+06 - - - 0.0196 - 1.788 0.257 - 79.1 1 2 0 0 13 0 0 0 3.53E+07 2.92E+07 - - - 2.9808 0.9999 221125_WJC_METTL3_EV_vs_WT_F02.17492.17492.2 0.000202 22-Dec R.EIFGLYGQTTGK.G "sp|Q9NR31|SAR1A_HUMAN,tr|H0Y5E8|H0Y5E8_HUMAN" 2 1312.6663 1.04 16991 17492 2 1312.667534 657.3404 GTP-binding protein SAR1a OS=Homo sapiens OX=9606 GN=SAR1A PE=1 SV=1 6.1 3203.1 - 2.09E+06 - - - 0.9271 - 2.46 0.486 - 426.3 1 2 0 0.0012 12 0 0 0 3.50E+08 3.36E+08 - - - 4.9987 0.9997 221125_WJC_METTL3_EV_vs_WT_F02.17493.17493.3 6.39E-06 15/48 R.FAPPLVIK[136.11]EDELR[166.11].E sp|P04181|OAT_HUMAN 1 1543.8729 1.23 16992 17493 3 1543.872894 515.6316 "Ornithine aminotransferase, mitochondrial OS=Homo sapiens OX=9606 GN=OAT PE=1 SV=1" 4.68 3203.2 - 1.48E+06 - - - -0.0039 - 3.038 0.378 - 215.1 1 2 1 0 13 0 0 0 2.60E+07 2.11E+07 - - - 5.7671 0.9999 221125_WJC_METTL3_EV_vs_WT_F02.17494.17494.2 5.67E-07 20-Nov R.YLVLDC[160.03]VPEER[166.11].R "sp|O14776|TCRG1_HUMAN,tr|A0A7P0T8N8|A0A7P0T8N8_HUMAN" 2 1401.6838 0.65 16993 17494 2 1401.685359 701.8492 Transcription elongation regulator 1 OS=Homo sapiens OX=9606 GN=TCERG1 PE=1 SV=2 4.14 3203.3 - 660597 - - - 1.1322 - 2.151 0.562 - 495.2 1 2 0 0.0016 11 0 0 0 4.61E+06 7.09E+06 - - - 5.2635 1 221125_WJC_METTL3_EV_vs_WT_F02.17495.17495.2 2.03E-08 26-Dec R.YGYGYNGMDLSVGR[166.11].S sp|P20719|HXA5_HUMAN 1 1560.6906 1.18 16994 17495 2 1560.686399 781.3526 Homeobox protein Hox-A5 OS=Homo sapiens OX=9606 GN=HOXA5 PE=1 SV=2 5.83 3203.4 - 389769 - - - -2.7225 - 2.834 0.714 - 291.3 1 2 0 -0.0042 14 0 0 0 6.52E+06 5.53E+06 - - - 6.9273 0.9999 221125_WJC_METTL3_EV_vs_WT_F02.17498.17498.2 0.00422 13/22 R.IAQLEAELALQK[136.11].K sp|Q15007|FL2D_HUMAN 1 1333.7697 0.92 16995 17498 2 1333.77015 667.8921 Pre-mRNA-splicing regulator WTAP OS=Homo sapiens OX=9606 GN=WTAP PE=1 SV=2 4.53 3203.8 - 594737 - - - 0.3621 - 2.837 0.446 - 665 1 2 0 0.0005 12 0 0 0 1.53E+07 1.66E+07 - - - 5.0786 0.9999 221125_WJC_METTL3_EV_vs_WT_F02.17505.17505.2 5.27E-06 18-Nov R.VGQALELPLR.L sp|Q8TEM1|PO210_HUMAN 1 1094.6448 2.16 17001 17505 2 1094.645554 548.3297 Nuclear pore membrane glycoprotein 210 OS=Homo sapiens OX=9606 GN=NUP210 PE=1 SV=3 5.97 3204.5 - 5.40E+06 - - - 0.6943 - 2.226 0.513 - 658.7 1 2 0 0.0008 10 0 0 0 9.22E+07 4.26E+07 - - - 5.0634 0.9904 221125_WJC_METTL3_EV_vs_WT_F02.17508.17508.2 0.95 16-Jun K.FQIEANFPR.R sp|Q96CS3|FAF2_HUMAN 1 1120.5665 1.01 17004 17508 2 1120.565622 561.2905 FAS-associated factor 2 OS=Homo sapiens OX=9606 GN=FAF2 PE=1 SV=2 6 3204.7 - 1.52E+06 - - - -0.8219 - 1.118 0.202 - 36 2 2 0 -0.0009 9 0 0 0 3.64E+07 3.61E+07 - - - 0.7209 0.9949 221125_WJC_METTL3_EV_vs_WT_F02.17509.17509.2 0.238 16-Jul R.NLLQVDLTK.R "sp|P22694|KAPCB_HUMAN,sp|P17612|KAPCA_HUMAN,tr|A0A087WVC4|A0A087WVC4_HUMAN,tr|A0A7I2V5J4|A0A7I2V5J4_HUMAN,tr|A0A0A0MS54|A0A0A0MS54_HUMAN" 5 1042.6023 1.34 17005 17509 2 1042.603569 522.3084 cAMP-dependent protein kinase catalytic subunit beta OS=Homo sapiens OX=9606 GN=PRKACB PE=1 SV=2 5.84 3204.8 - 1.11E+06 - - - 1.2555 - 1.531 0.151 - 120.5 1 2 0 0.0013 9 0 0 0 1.42E+07 1.06E+07 - - - 1.3881 0.9977 221125_WJC_METTL3_EV_vs_WT_F02.17511.17511.2 0.0328 20-Aug K.FLEEQEITDLK.V sp|O60825|F262_HUMAN 1 1363.6871 3.59 17007 17511 2 1363.691548 682.8508 "6-phosphofructo-2-kinase\fructose-2,6-bisphosphatase 2 OS=Homo sapiens OX=9606 GN=PFKFB2 PE=1 SV=2" 4 3205 - 760826 - - - 3.2529 - 1.853 0.337 - 165.7 1 2 0 0.0044 11 0 0 0 5.31E+07 1.48E+07 - - - 3.1973 0.9969 221125_WJC_METTL3_EV_vs_WT_F02.17513.17513.2 0.0771 22-Sep R.NQLTAMSSVLAK[136.11].A sp|Q14152|EIF3A_HUMAN 1 1269.6842 1.07 17009 17513 2 1269.679221 635.8494 Eukaryotic translation initiation factor 3 subunit A OS=Homo sapiens OX=9606 GN=EIF3A PE=1 SV=1 8.75 3205.2 - 497662 - - - -3.9388 - 2.06 0.336 - 246.6 1 2 0 -0.005 12 0 0 0 5.26E+07 4.93E+07 - - - 3.4227 0.9999 221125_WJC_METTL3_EV_vs_WT_F02.17517.17517.2 3.06E-07 20-Nov K.GPLQSVQVFGR[166.11].K "sp|P62249|RS16_HUMAN,tr|M0R210|M0R210_HUMAN,tr|M0R3H0|M0R3H0_HUMAN,tr|Q6IPX4|Q6IPX4_HUMAN" 4 1196.6541 0.58 17012 17517 2 1196.655402 599.3343 40S ribosomal protein S16 OS=Homo sapiens OX=9606 GN=RPS16 PE=1 SV=2 9.75 3205.7 - 3.62E+07 - - - 1.0663 - 2.539 0.562 - 473.6 1 2 0 0.0013 11 0 0 0 1.77E+09 3.03E+09 - - - 5.7122 0.9999 221125_WJC_METTL3_EV_vs_WT_F02.17520.17520.2 0.000169 13/22 R.NQLTAMSSVLAK.A sp|Q14152|EIF3A_HUMAN 1 1261.67 1.07 17014 17520 2 1261.668595 631.8423 Eukaryotic translation initiation factor 3 subunit A OS=Homo sapiens OX=9606 GN=EIF3A PE=1 SV=1 8.75 3206 - 1.06E+06 - - - -1.131 - 2.763 0.467 - 658.9 1 2 0 -0.0014 12 0 0 0 5.30E+07 4.95E+07 - - - 5.1639 0.9976 221125_WJC_METTL3_EV_vs_WT_F02.17521.17521.2 0.211 16-Sep K.FNFGEEEFK.F "sp|Q92499|DDX1_HUMAN,tr|A0A7I2V2M5|A0A7I2V2M5_HUMAN,tr|A0A087X2G1|A0A087X2G1_HUMAN,tr|A0A7I2V430|A0A7I2V430_HUMAN,tr|A0A7I2V421|A0A7I2V421_HUMAN,tr|A0A7I2V4F0|A0A7I2V4F0_HUMAN,tr|A0A7I2V5X8|A0A7I2V5X8_HUMAN,tr|A0A7I2V4J3|A0A7I2V4J3_HUMAN,tr|A0A087WZ71|A0A087WZ71_HUMAN,tr|A0A7I2YQ77|A0A7I2YQ77_HUMAN" 10 1145.5029 1.24 17015 17521 2 1145.49949 573.7587 ATP-dependent RNA helicase DDX1 OS=Homo sapiens OX=9606 GN=DDX1 PE=1 SV=2 4.25 3206.1 - 2.06E+06 - - - -3.0118 - 1.643 0.336 - 201 1 2 0 -0.0034 9 0 0 0 2.10E+07 1.70E+07 - - - 2.9581 0.9974 221125_WJC_METTL3_EV_vs_WT_F02.17523.17523.2 0.458 12-Jul R.RTPDYFL.- "sp|P67775|PP2AA_HUMAN,sp|P62714|PP2AB_HUMAN,tr|H0YBN9|H0YBN9_HUMAN" 3 910.4549 0.79 17017 17523 2 910.455088 456.2347 Serine\threonine-protein phosphatase 2A catalytic subunit alpha isoform OS=Homo sapiens OX=9606 GN=PPP2CA PE=1 SV=1 5.84 3206.2 - 1.02E+06 - - - 0.2416 - 1.339 0.222 - 168 1 2 0 0.0002 7 0 0 0 1.64E+07 2.08E+07 - - - 1.6056 0.9999 221125_WJC_METTL3_EV_vs_WT_F02.17524.17524.2 0.00484 13/22 R.IAQLEAELALQK.K sp|Q15007|FL2D_HUMAN 1 1325.7555 0.92 17018 17524 2 1325.754639 663.885 Pre-mRNA-splicing regulator WTAP OS=Homo sapiens OX=9606 GN=WTAP PE=1 SV=2 4.53 3206.3 - 1.01E+06 - - - -0.6245 - 2.669 0.429 - 706.3 1 2 0 -0.0008 12 0 0 0 1.53E+07 1.66E+07 - - - 4.7924 0.9998 221125_WJC_METTL3_EV_vs_WT_F02.17525.17525.2 0.00208 16-Sep R.NLFNVVDC[160.03]K[136.11].L sp|P55884|EIF3B_HUMAN 1 1115.5525 1.32 17019 17525 2 1115.551469 558.7835 Eukaryotic translation initiation factor 3 subunit B OS=Homo sapiens OX=9606 GN=EIF3B PE=1 SV=3 5.83 3206.4 - 991938 - - - -0.9063 - 1.87 0.459 - 201.6 1 2 0 -0.001 9 0 0 0 3.16E+07 2.40E+07 - - - 4.2417 0.9997 221125_WJC_METTL3_EV_vs_WT_F02.17526.17526.2 0.0576 22-Dec R.IAAAILNTPDLR.K sp|P00505|AATM_HUMAN 1 1266.7296 1.03 17020 17526 2 1266.731654 634.3721 "Aspartate aminotransferase, mitochondrial OS=Homo sapiens OX=9606 GN=GOT2 PE=1 SV=3" 5.84 3206.5 - 971023 - - - 1.6326 - 2.809 0.338 - 692 1 2 0 0.0021 12 0 0 0 1.23E+07 1.19E+07 - - - 4.2544 0.9739 221125_WJC_METTL3_EV_vs_WT_F02.17527.17527.2 0.000778 20-Aug S.SIPLQGAFNYK.Y sp|P12273|PIP_HUMAN 1 1236.6503 10.44 17021 17527 2 1236.650258 619.3324 Prolactin-inducible protein OS=Homo sapiens OX=9606 GN=PIP PE=1 SV=1 8.31 3206.6 - 842773 - - - -0.0121 - 1.558 0.392 - 195.1 1 1 0 0 11 0 0 0 2.77E+07 2.65E+06 - - - 3.1358 0.9997 221125_WJC_METTL3_EV_vs_WT_F02.17528.17528.2 0.000211 24-Oct K.TILPAAAQDVYYR[166.11].D "sp|P04843|RPN1_HUMAN,tr|B7Z4L4|B7Z4L4_HUMAN" 2 1489.7804 1.16 17022 17528 2 1489.782524 745.8975 Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit 1 OS=Homo sapiens OX=9606 GN=RPN1 PE=1 SV=1 5.5 3206.7 - 796322 - - - 1.3928 - 1.978 0.478 - 303.5 1 2 0 0.0021 13 0 0 0 1.25E+07 1.07E+07 - - - 4.3215 0.7932 221125_WJC_METTL3_EV_vs_WT_F02.17529.17529.2 0.398 May-32 R.NVEVTMFIVDSSGQTLK.D "sp|Q8N1I0|DOCK4_HUMAN,tr|H0Y599|H0Y599_HUMAN,tr|F5GXW1|F5GXW1_HUMAN" 3 1866.9397 -1 17023 17529 2 1866.9277 934.4771 Dedicator of cytokinesis protein 4 OS=Homo sapiens OX=9606 GN=DOCK4 PE=1 SV=3 4.37 3206.8 - 153407 - - - -6.4357 - 1.026 0.272 - 41 1 2 0 -0.012 17 0 0 0 0.00E+00 0.00E+00 - - - 1.1093 0.9968 221125_WJC_METTL3_EV_vs_WT_F02.17531.17531.2 0.00882 14-Sep K.GIAYIEFK.T "sp|P19338|NUCL_HUMAN,tr|A0A7I2V506|A0A7I2V506_HUMAN,tr|A0A7I2V2U7|A0A7I2V2U7_HUMAN,tr|A0A7I2V3F3|A0A7I2V3F3_HUMAN,tr|A0A7I2V428|A0A7I2V428_HUMAN,tr|A0A7I2V349|A0A7I2V349_HUMAN,tr|H7BY16|H7BY16_HUMAN,tr|A0A7I2V5M5|A0A7I2V5M5_HUMAN,tr|C9JLB1|C9JLB1_HUMAN" 9 939.5066 0.98 17024 17531 2 939.506959 470.7606 Nucleolin OS=Homo sapiens OX=9606 GN=NCL PE=1 SV=3 6 3207 - 2.37E+06 - - - 0.4151 - 1.666 0.121 - 273.8 1 2 0 0.0004 8 0 0 0 9.48E+07 9.65E+07 - - - 1.474 0.9997 221125_WJC_METTL3_EV_vs_WT_F02.17533.17533.2 0.566 16-Oct R.TEIIILATR[166.11].T "sp|P23396|RS3_HUMAN,tr|H0YEU2|H0YEU2_HUMAN,tr|E9PL09|E9PL09_HUMAN,tr|E9PK82|E9PK82_HUMAN,tr|F2Z2S8|F2Z2S8_HUMAN,tr|H0YCJ7|H0YCJ7_HUMAN,tr|E9PQ96|E9PQ96_HUMAN,tr|E9PJH4|E9PJH4_HUMAN,tr|E9PPU1|E9PPU1_HUMAN,tr|H0YF32|H0YF32_HUMAN" 10 1038.6313 0.76 17025 17533 2 1038.630442 520.3229 40S ribosomal protein S3 OS=Homo sapiens OX=9606 GN=RPS3 PE=1 SV=2 5.66 3207.2 - 2.18E+06 - - - -0.7934 - 2.089 0.343 - 456 1 2 0 -0.0008 9 0 0 0 1.79E+08 2.35E+08 - - - 3.7054 0.9988 221125_WJC_METTL3_EV_vs_WT_F02.17534.17534.2 0.0418 16-Aug K.EVLSLLQEK[136.11].N "sp|Q6UB35|C1TM_HUMAN,tr|A0A087WVM4|A0A087WVM4_HUMAN,tr|B7ZM99|B7ZM99_HUMAN,tr|H0Y327|H0Y327_HUMAN" 4 1065.6161 1.74 17026 17534 2 1065.616987 533.8153 "Monofunctional C1-tetrahydrofolate synthase, mitochondrial OS=Homo sapiens OX=9606 GN=MTHFD1L PE=1 SV=1" 4.53 3207.3 - 1.28E+06 - - - 0.808 - 1.629 0.263 - 186.6 1 2 0 0.0009 9 0 0 0 5.19E+07 2.99E+07 - - - 2.395 0.9633 221125_WJC_METTL3_EV_vs_WT_F02.17537.17537.2 6.75 14-Jun K.LFIGNLPR.E "sp|Q9BWF3|RBM4_HUMAN,sp|Q9BQ04|RBM4B_HUMAN,tr|E9PM61|E9PM61_HUMAN,tr|D6R9K7|D6R9K7_HUMAN,tr|J3QRR5|J3QRR5_HUMAN,tr|E9PB51|E9PB51_HUMAN,tr|U3KQD5|U3KQD5_HUMAN,tr|E9PLB0|E9PLB0_HUMAN" 8 928.5494 1.5 17029 17537 2 928.551506 465.282 RNA-binding protein 4 OS=Homo sapiens OX=9606 GN=RBM4 PE=1 SV=1 9.75 3207.6 - 1.32E+06 - - - 2.2282 - 1.277 0.12 - 89.7 4 2 0 0.0021 8 0 0 0 8.49E+07 5.66E+07 - - - 0.3952 0.9998 221125_WJC_METTL3_EV_vs_WT_F02.17538.17538.2 0.000242 18-Sep R.GYFEYIEENK[136.11].Y "sp|Q00839|HNRPU_HUMAN,tr|Q5RI18|Q5RI18_HUMAN,tr|A0A1W2PP35|A0A1W2PP35_HUMAN,tr|A0A1W2PPS1|A0A1W2PPS1_HUMAN,tr|A0A1W2PRI6|A0A1W2PRI6_HUMAN" 5 1298.591 1.06 17030 17538 2 1298.590497 650.3028 Heterogeneous nuclear ribonucleoprotein U OS=Homo sapiens OX=9606 GN=HNRNPU PE=1 SV=6 4.25 3207.6 - 1.06E+06 - - - -0.4128 - 2.132 0.444 - 197.8 1 2 0 -0.0005 10 0 0 0 6.75E+07 6.37E+07 - - - 4.4334 0.9998 221125_WJC_METTL3_EV_vs_WT_F02.17539.17539.2 0.00221 15/22 R.IAAAILNTPDLR[166.11].K sp|P00505|AATM_HUMAN 1 1276.7379 1.03 17031 17539 2 1276.738456 639.3762 "Aspartate aminotransferase, mitochondrial OS=Homo sapiens OX=9606 GN=GOT2 PE=1 SV=3" 5.84 3207.7 - 877105 - - - 0.4699 - 2.727 0.324 - 1183.2 1 2 0 0.0006 12 0 0 0 1.23E+07 1.19E+07 - - - 4.0735 0.9936 221125_WJC_METTL3_EV_vs_WT_F02.17540.17540.2 0.0132 18-Sep K.LFPETWTAEK[136.11].L sp|Q9P032|NDUF4_HUMAN 1 1228.6219 3.34 17032 17540 2 1228.617536 615.3182 NADH dehydrogenase [ubiquinone] 1 alpha subcomplex assembly factor 4 OS=Homo sapiens OX=9606 GN=NDUFAF4 PE=1 SV=1 4.53 3207.8 - 769144 - - - -3.5845 - 1.558 0.292 - 263.9 1 2 0 -0.0044 10 0 0 0 4.82E+07 1.44E+07 - - - 2.434 0.9862 221125_WJC_METTL3_EV_vs_WT_F02.17541.17541.2 0.332 12-Aug R.NQLPFLR.N sp|Q9ULV0|MYO5B_HUMAN 1 886.5025 2.08 17033 17541 2 886.501627 444.2585 Unconventional myosin-Vb OS=Homo sapiens OX=9606 GN=MYO5B PE=1 SV=3 9.75 3207.9 - 575735 - - - -0.9701 - 1.433 0.045 - 324.8 1 2 0 -0.0009 7 0 0 0 1.14E+07 5.45E+06 - - - 0.5131 0.97 221125_WJC_METTL3_EV_vs_WT_F02.17542.17542.2 0.325 12-Jun K.FSIEDLK[136.11].A sp|Q9P016|THYN1_HUMAN 1 858.4578 0.42 17034 17542 2 858.458295 430.2362 Thymocyte nuclear protein 1 OS=Homo sapiens OX=9606 GN=THYN1 PE=1 SV=1 4.37 3208 - 567646 - - - 0.537 - 1.373 0.006 - 87.2 2 2 0 0.0005 7 0 0 0 7.19E+06 1.72E+07 - - - -0.0449 0.993 221125_WJC_METTL3_EV_vs_WT_F02.17546.17546.2 1.32E-06 Oct-32 R.VYTADPYHALAPAASYG.V "sp|O43251|RFOX2_HUMAN,tr|B0QYV1|B0QYV1_HUMAN,tr|A0A0G2JRD1|A0A0G2JRD1_HUMAN,tr|A0A0G2JRA5|A0A0G2JRA5_HUMAN,tr|S4R3K7|S4R3K7_HUMAN" 5 1765.8312 - 17038 17546 2 1765.831995 883.9229 RNA binding protein fox-1 homolog 2 OS=Homo sapiens OX=9606 GN=RBFOX2 PE=1 SV=3 5.08 3208.6 - 313581 - - - 0.478 - 1.904 0.602 - 162.8 1 1 0 0.0008 17 0 0 0 - - - - - 5.0703 0.9982 221125_WJC_METTL3_EV_vs_WT_F02.17550.17550.2 0.162 16-Aug R.MQFGVPLAR.N "sp|Q92947|GCDH_HUMAN,tr|K7ESA6|K7ESA6_HUMAN" 2 1017.543 1.21 17040 17550 2 1017.543207 509.7788 "Glutaryl-CoA dehydrogenase, mitochondrial OS=Homo sapiens OX=9606 GN=GCDH PE=1 SV=1" 9.5 3209 - 3.25E+06 - - - 0.2319 - 1.398 0.255 - 253.1 1 2 0 0.0002 9 0 0 0 8.66E+07 7.18E+07 - - - 1.8937 0.9995 221125_WJC_METTL3_EV_vs_WT_F02.17551.17551.2 0.137 16-Nov R.TEIIILATR.T "sp|P23396|RS3_HUMAN,tr|H0YEU2|H0YEU2_HUMAN,tr|E9PL09|E9PL09_HUMAN,tr|E9PK82|E9PK82_HUMAN,tr|F2Z2S8|F2Z2S8_HUMAN,tr|H0YCJ7|H0YCJ7_HUMAN,tr|E9PQ96|E9PQ96_HUMAN,tr|E9PJH4|E9PJH4_HUMAN,tr|E9PPU1|E9PPU1_HUMAN,tr|H0YF32|H0YF32_HUMAN" 10 1028.623 0.78 17041 17551 2 1028.624059 515.3188 40S ribosomal protein S3 OS=Homo sapiens OX=9606 GN=RPS3 PE=1 SV=2 5.66 3209 - 3.06E+06 - - - 1.0334 - 2.027 0.317 - 635.9 1 2 0 0.0011 9 0 0 0 1.84E+08 2.35E+08 - - - 3.4261 0.9911 221125_WJC_METTL3_EV_vs_WT_F02.17552.17552.2 0.000675 18-Nov A.MVWEGYNVVR.A "sp|O00746|NDKM_HUMAN,tr|Q4TT34|Q4TT34_HUMAN,tr|H0Y6J0|H0Y6J0_HUMAN,tr|F2Z2X0|F2Z2X0_HUMAN" 4 1251.607 1.93 17042 17552 2 1251.607503 626.8108 "Nucleoside diphosphate kinase, mitochondrial OS=Homo sapiens OX=9606 GN=NME4 PE=1 SV=1" 5.75 3209.1 - 2.14E+06 - - - 0.3795 - 1.883 0.513 - 450.4 1 1 0 0.0005 10 0 0 0 8.95E+07 4.63E+07 - - - 4.5964 0.9989 221125_WJC_METTL3_EV_vs_WT_F02.17553.17553.2 0.0136 16-Sep K.EVLSLLQEK.N "sp|Q6UB35|C1TM_HUMAN,tr|A0A087WVM4|A0A087WVM4_HUMAN,tr|B7ZM99|B7ZM99_HUMAN,tr|H0Y327|H0Y327_HUMAN" 4 1057.6019 1.19 17043 17553 2 1057.603094 529.8082 "Monofunctional C1-tetrahydrofolate synthase, mitochondrial OS=Homo sapiens OX=9606 GN=MTHFD1L PE=1 SV=1" 4.53 3209.2 - 1.92E+06 - - - 1.1044 - 1.717 0.271 - 244.7 1 2 0 0.0012 9 0 0 0 3.36E+07 2.82E+07 - - - 2.6062 0.9997 221125_WJC_METTL3_EV_vs_WT_F02.17554.17554.2 0.000473 18-Sep R.GYFEYIEENK.Y "sp|Q00839|HNRPU_HUMAN,tr|Q5RI18|Q5RI18_HUMAN,tr|A0A1W2PP35|A0A1W2PP35_HUMAN,tr|A0A1W2PPS1|A0A1W2PPS1_HUMAN,tr|A0A1W2PRI6|A0A1W2PRI6_HUMAN" 5 1290.5768 1.02 17044 17554 2 1290.578616 646.2957 Heterogeneous nuclear ribonucleoprotein U OS=Homo sapiens OX=9606 GN=HNRNPU PE=1 SV=6 4.25 3209.2 - 1.77E+06 - - - 1.3816 - 1.937 0.451 - 244.3 1 2 0 0.0018 10 0 0 0 6.75E+07 6.61E+07 - - - 4.217 0.9999 221125_WJC_METTL3_EV_vs_WT_F02.17556.17556.3 5.75E-05 14/64 R.IINEPTAAAIAYGLDKK.G "sp|P54652|HSP72_HUMAN,sp|P11142|HSP7C_HUMAN,tr|E9PKE3|E9PKE3_HUMAN,tr|E9PN89|E9PN89_HUMAN,tr|E9PI65|E9PI65_HUMAN" 5 1786.9829 0.37 17046 17556 3 1786.984626 596.6682 Heat shock-related 70 kDa protein 2 OS=Homo sapiens OX=9606 GN=HSPA2 PE=1 SV=1 6.07 3209.4 - 1.45E+06 - - - 0.9659 - 2.562 0.435 - 139.7 1 2 0 0.0017 17 0 0 0 1.45E+07 3.88E+07 - - - 5.7661 0.9938 221125_WJC_METTL3_EV_vs_WT_F02.17557.17557.2 0.978 12-Jun K.YLWNNIK[136.11].R "sp|P04632|CPNS1_HUMAN,sp|Q96L46|CPNS2_HUMAN,tr|A0A075B7C0|A0A075B7C0_HUMAN,tr|A0A0C4DGQ5|A0A0C4DGQ5_HUMAN,tr|K7ELJ7|K7ELJ7_HUMAN,tr|U3KPR7|U3KPR7_HUMAN,tr|U3KQE2|U3KQE2_HUMAN,tr|K7EIV0|K7EIV0_HUMAN,tr|K7EKD8|K7EKD8_HUMAN" 9 957.5164 1.1 17047 17557 2 957.517604 479.7655 Calpain small subunit 1 OS=Homo sapiens OX=9606 GN=CAPNS1 PE=1 SV=1 8.59 3209.4 - 1.34E+06 - - - 1.3075 - 1.077 0.268 - 100.2 1 2 0 0.0013 7 0 0 0 2.40E+07 2.18E+07 - - - 1.2551 0.9982 221125_WJC_METTL3_EV_vs_WT_F02.17558.17558.2 0.12 12-Jul K.YLWNNIK.R "sp|P04632|CPNS1_HUMAN,sp|Q96L46|CPNS2_HUMAN,tr|A0A075B7C0|A0A075B7C0_HUMAN,tr|A0A0C4DGQ5|A0A0C4DGQ5_HUMAN,tr|K7ELJ7|K7ELJ7_HUMAN,tr|U3KPR7|U3KPR7_HUMAN,tr|U3KQE2|U3KQE2_HUMAN,tr|K7EIV0|K7EIV0_HUMAN,tr|K7EKD8|K7EKD8_HUMAN" 9 949.5022 1.1 17048 17558 2 949.501557 475.7584 Calpain small subunit 1 OS=Homo sapiens OX=9606 GN=CAPNS1 PE=1 SV=1 8.59 3209.5 - 1.27E+06 - - - -0.6266 - 1.24 0.295 - 138.9 1 2 0 -0.0006 7 0 0 0 2.40E+07 2.18E+07 - - - 1.9013 0.9982 221125_WJC_METTL3_EV_vs_WT_F02.17559.17559.2 0.718 14-Aug K.LFIGNLPR[166.11].E "sp|Q9BWF3|RBM4_HUMAN,sp|Q9BQ04|RBM4B_HUMAN,tr|E9PM61|E9PM61_HUMAN,tr|D6R9K7|D6R9K7_HUMAN,tr|J3QRR5|J3QRR5_HUMAN,tr|E9PB51|E9PB51_HUMAN,tr|U3KQD5|U3KQD5_HUMAN,tr|E9PLB0|E9PLB0_HUMAN" 8 938.5577 1.52 17049 17559 2 938.557062 470.2861 RNA-binding protein 4 OS=Homo sapiens OX=9606 GN=RBM4 PE=1 SV=1 9.75 3209.6 - 1.22E+06 - - - -0.6872 - 1.557 0.212 - 223.3 1 2 0 -0.0006 8 0 0 0 8.43E+07 5.55E+07 - - - 1.942 0.9999 221125_WJC_METTL3_EV_vs_WT_F02.17561.17561.2 0.000417 22-Dec R.IAEEVNC[160.03]LLAC[160.03]R.D "sp|Q6KC79|NIPBL_HUMAN,tr|A0A590UJS4|A0A590UJS4_HUMAN" 2 1446.6959 1.02 17051 17561 2 1446.694733 724.3552 Nipped-B-like protein OS=Homo sapiens OX=9606 GN=NIPBL PE=1 SV=2 4.53 3209.9 - 520662 - - - -0.8205 - 2.701 0.428 - 604.9 1 2 0 -0.0012 12 0 0 0 5.98E+06 5.88E+06 - - - 4.8162 0.9901 221125_WJC_METTL3_EV_vs_WT_F02.17563.17563.2 1.15 12-Jun K.FSIEDLK.A sp|Q9P016|THYN1_HUMAN 1 850.4436 0.29 17053 17563 2 850.443227 426.2291 Thymocyte nuclear protein 1 OS=Homo sapiens OX=9606 GN=THYN1 PE=1 SV=1 4.37 3210.1 - 468187 - - - -0.4786 - 1.425 0.083 - 101 2 2 0 -0.0004 7 0 0 0 7.53E+06 2.63E+07 - - - 0.6417 0.9989 221125_WJC_METTL3_EV_vs_WT_F02.17566.17566.2 0.103 22-Dec R.IAEEVNC[160.03]LLAC[160.03]R[166.11].D "sp|Q6KC79|NIPBL_HUMAN,tr|A0A590UJS4|A0A590UJS4_HUMAN" 2 1456.7042 1.06 17056 17566 2 1456.704535 729.3594 Nipped-B-like protein OS=Homo sapiens OX=9606 GN=NIPBL PE=1 SV=2 4.53 3210.5 - 356360 - - - 0.2368 - 1.924 0.209 - 265.4 1 2 0 0.0003 12 0 0 0 7.15E+06 6.72E+06 - - - 2.3064 0.9998 221125_WJC_METTL3_EV_vs_WT_F02.17569.17569.2 0.000255 16-Sep R.NLFNVVDC[160.03]K.L sp|P55884|EIF3B_HUMAN 1 1107.5383 1.31 17058 17569 2 1107.538352 554.7764 Eukaryotic translation initiation factor 3 subunit B OS=Homo sapiens OX=9606 GN=EIF3B PE=1 SV=3 5.83 3210.8 - 2.56E+06 - - - 0.065 - 1.917 0.452 - 321.5 1 2 0 0.0001 9 0 0 0 3.17E+07 2.41E+07 - - - 4.2621 0.9994 221125_WJC_METTL3_EV_vs_WT_F02.17570.17570.2 0.00482 12-Jul K.DNWLLAK[136.11].S "sp|Q8NI27|THOC2_HUMAN,tr|A0A0C4DG98|A0A0C4DG98_HUMAN,tr|H0Y815|H0Y815_HUMAN" 3 866.4742 2.38 17059 17570 2 866.473859 434.2444 THO complex subunit 2 OS=Homo sapiens OX=9606 GN=THOC2 PE=1 SV=2 5.84 3211 - 399224 - - - -0.3393 - 1.632 0.306 - 232.6 1 2 0 -0.0003 7 0 0 0 1.49E+07 6.26E+06 - - - 2.853 0.9694 221125_WJC_METTL3_EV_vs_WT_F02.17573.17573.2 0.00255 14/24 K.TILPAAAQDVYYR.D "sp|P04843|RPN1_HUMAN,tr|B7Z4L4|B7Z4L4_HUMAN" 2 1479.7722 0.28 17062 17573 2 1479.781676 740.8934 Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit 1 OS=Homo sapiens OX=9606 GN=RPN1 PE=1 SV=1 5.5 3211.2 - 748310 - - - 6.4179 - 2.233 0.231 - 677.5 1 2 0 0.0095 13 0 0 0 1.28E+07 4.64E+07 - - - 2.806 0.999 221125_WJC_METTL3_EV_vs_WT_F02.17575.17575.2 0.0115 13/24 R.VALSPAGVQNLVK[136.11].Q "sp|Q13423|NNTM_HUMAN,tr|D6RHU2|D6RHU2_HUMAN,tr|A0A590UJA4|A0A590UJA4_HUMAN,tr|D6RAI5|D6RAI5_HUMAN,tr|A0A590UK15|A0A590UK15_HUMAN,tr|A0A590UJM2|A0A590UJM2_HUMAN,tr|A0A590UK29|A0A590UK29_HUMAN,tr|A0A590UKC7|A0A590UKC7_HUMAN" 8 1302.7751 0.99 17064 17575 2 1302.779372 652.3948 "NAD(P) transhydrogenase, mitochondrial OS=Homo sapiens OX=9606 GN=NNT PE=1 SV=3" 8.72 3211.5 - 522359 - - - 3.2899 - 2.182 0.429 - 410.7 1 2 0 0.0043 13 0 0 0 1.59E+07 1.61E+07 - - - 4.2108 0.9997 221125_WJC_METTL3_EV_vs_WT_F02.17576.17576.2 2.27E-05 26-Aug R.LFPPDDSPLPVSSR.V "sp|Q05519|SRS11_HUMAN,tr|Q5T760|Q5T760_HUMAN,tr|B4DWT1|B4DWT1_HUMAN" 3 1525.7777 1.72 17065 17576 2 1525.778302 763.8961 Serine\arginine-rich splicing factor 11 OS=Homo sapiens OX=9606 GN=SRSF11 PE=1 SV=1 4.21 3211.6 - 492859 - - - 0.4214 - 1.714 0.432 - 66.7 1 2 0 0.0006 14 0 0 0 2.35E+07 1.36E+07 - - - 3.5837 0.9825 221125_WJC_METTL3_EV_vs_WT_F02.17578.17578.3 0.00117 Dec-44 Q.GLDC[160.03]DVIVAEVR[166.11].S sp|Q86U44|MTA70_HUMAN 1 1354.679 0.25 17067 17578 3 1354.676876 452.567 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 4.03 3211.9 - 431062 - - - -1.5834 - 2.24 0.378 - 222.6 1 1 0 -0.0021 12 0 0 0 1.71E+06 6.91E+06 - - - 4.9892 0.9984 221125_WJC_METTL3_EV_vs_WT_F02.17582.17582.2 0.449 18-Sep K.IDFVGELNDK.M "sp|A6NEC2|PSAL_HUMAN,sp|P55786|PSA_HUMAN,tr|A0A7I2V3W8|A0A7I2V3W8_HUMAN,tr|E9PP11|E9PP11_HUMAN,tr|E9PPZ2|E9PPZ2_HUMAN,tr|E9PJY4|E9PJY4_HUMAN,tr|A0A7I2V389|A0A7I2V389_HUMAN,tr|E9PLK3|E9PLK3_HUMAN,tr|E9PPD4|E9PPD4_HUMAN,tr|A0A7I2V604|A0A7I2V604_HUMAN" 10 1148.5714 4.01 17070 17582 2 1148.572446 575.293 Puromycin-sensitive aminopeptidase-like protein OS=Homo sapiens OX=9606 GN=NPEPPSL1 PE=2 SV=3 4.03 3212.4 - 1.44E+06 - - - 0.9507 - 1.992 0.166 - 194.1 1 2 0 0.0011 10 0 0 0 2.80E+08 6.98E+07 - - - 2.1903 0.9996 221125_WJC_METTL3_EV_vs_WT_F02.17584.17584.2 0.00216 18-Dec K.FAEAFEAIPR[166.11].A sp|P50990|TCPQ_HUMAN 1 1159.5901 0.41 17071 17584 2 1159.593642 580.8023 T-complex protein 1 subunit theta OS=Homo sapiens OX=9606 GN=CCT8 PE=1 SV=4 4.53 3212.6 - 2.40E+06 - - - 3.0295 - 2.397 0.538 - 524.5 1 2 0 0.0035 10 0 0 0 4.89E+08 1.18E+09 - - - 5.4538 0.9997 221125_WJC_METTL3_EV_vs_WT_F02.17588.17588.3 0.018 Dec-36 R.SLGVHLSFIR[166.11].S "sp|Q9NP61|ARFG3_HUMAN,sp|Q8N6H7|ARFG2_HUMAN,tr|E9PMU9|E9PMU9_HUMAN,tr|B0QYV9|B0QYV9_HUMAN,tr|E9PNY8|E9PNY8_HUMAN,tr|H0YDX1|H0YDX1_HUMAN,tr|E9PIY6|E9PIY6_HUMAN,tr|E9PQP3|E9PQP3_HUMAN,tr|E9PJT7|E9PJT7_HUMAN,tr|B0QYV8|B0QYV8_HUMAN,tr|E9PMR9|E9PMR9_HUMAN,tr|E9PN48|E9PN48_HUMAN,tr|E9PK28|E9PK28_HUMAN,tr|E9PM63|E9PM63_HUMAN,tr|G5E9L0|G5E9L0_HUMAN,tr|A0A0D9SF70|A0A0D9SF70_HUMAN" 16 1137.6534 0.001 17075 17588 3 1137.65263 380.2251 ADP-ribosylation factor GTPase-activating protein 3 OS=Homo sapiens OX=9606 GN=ARFGAP3 PE=1 SV=1 9.49 3213 - 506722 - - - -0.6751 - 1.728 0.38 - 214.8 1 2 0 -0.0008 10 0 0 0 0.00E+00 8.64E+06 - - - 4.3738 0.9999 221125_WJC_METTL3_EV_vs_WT_F02.17589.17589.2 2.93E-07 24-Nov K.LVLTNNQLTTLPR[166.11].G "sp|Q9UQ13|SHOC2_HUMAN,tr|X6RI37|X6RI37_HUMAN" 2 1491.8648 0.09 17076 17589 2 1491.862345 746.9397 Leucine-rich repeat protein SHOC-2 OS=Homo sapiens OX=9606 GN=SHOC2 PE=1 SV=2 9.75 3213.2 - 282349 - - - -1.6778 - 2.543 0.562 - 458.2 1 2 0 -0.0025 13 0 0 0 3.35E+05 3.59E+06 - - - 5.5866 0.9998 221125_WJC_METTL3_EV_vs_WT_F02.17590.17590.3 0.101 Dec-40 R.LMDLLGEGLKR.S sp|P54136|SYRC_HUMAN 1 1243.6958 0.88 17077 17590 3 1243.69716 415.5726 "Arginine--tRNA ligase, cytoplasmic OS=Homo sapiens OX=9606 GN=RARS1 PE=1 SV=2" 6.07 3213.3 - 261829 - - - 1.0589 - 2.385 0.322 - 144.4 1 2 0 0.0013 11 0 0 0 3.99E+07 4.52E+07 - - - 4.5989 1 221125_WJC_METTL3_EV_vs_WT_F02.17595.17595.2 7.70E-07 18-Nov K.C[160.03]LAYDFYPGK.L sp|P25311|ZA2G_HUMAN 1 1232.5536 598.5 17080 17595 2 1232.554373 617.2841 Zinc-alpha-2-glycoprotein OS=Homo sapiens OX=9606 GN=AZGP1 PE=1 SV=2 5.83 3214 - 4.79E+06 - - - 0.6304 - 2.376 0.588 - 420.9 1 2 0 0.0008 10 0 0 0 1.49E+08 2.49E+05 - - - 5.7994 0.988 221125_WJC_METTL3_EV_vs_WT_F02.17596.17596.2 0.000616 18-Oct A.MVWEGYNVVR[166.11].A "sp|O00746|NDKM_HUMAN,tr|Q4TT34|Q4TT34_HUMAN,tr|H0Y6J0|H0Y6J0_HUMAN,tr|F2Z2X0|F2Z2X0_HUMAN" 4 1261.6153 2.82 17081 17596 2 1261.616237 631.8149 "Nucleoside diphosphate kinase, mitochondrial OS=Homo sapiens OX=9606 GN=NME4 PE=1 SV=1" 5.75 3214 - 4.01E+06 - - - 0.7443 - 1.848 0.48 - 392.2 1 1 0 0.0009 10 0 0 0 1.40E+08 4.97E+07 - - - 4.3001 0.999 221125_WJC_METTL3_EV_vs_WT_F02.17597.17597.2 0.523 16-Aug R.EPLSLINVR[166.11].K sp|Q96HS1|PGAM5_HUMAN 1 1049.6109 0.82 17082 17597 2 1049.612159 525.8127 "Serine\threonine-protein phosphatase PGAM5, mitochondrial OS=Homo sapiens OX=9606 GN=PGAM5 PE=1 SV=2" 6.1 3214.1 - 1.44E+06 - - - 1.2328 - 1.755 0.282 - 231.9 1 2 0 0.0013 9 0 0 0 4.15E+07 5.04E+07 - - - 2.7507 1 221125_WJC_METTL3_EV_vs_WT_F02.17598.17598.2 5.75E-09 15/30 K.TVEGAGSIAAATGFVK.K "sp|P37840|SYUA_HUMAN,tr|A0A669KB41|A0A669KB41_HUMAN,tr|A0A669KBH5|A0A669KBH5_HUMAN,tr|H6UYS7|H6UYS7_HUMAN,tr|E7EPV7|E7EPV7_HUMAN" 5 1477.7777 1.73 17083 17598 2 1477.78441 739.8961 Alpha-synuclein OS=Homo sapiens OX=9606 GN=SNCA PE=1 SV=1 5.66 3214.1 - 1.03E+06 - - - 4.5683 - 2.9 0.6 - 452.9 1 2 0 0.0068 16 0 0 0 9.15E+06 5.28E+06 - - - 6.0881 0.9999 221125_WJC_METTL3_EV_vs_WT_F02.17599.17599.3 0.217 15/40 R.LMDLLGEGLK[136.11]R[166.11].S sp|P54136|SYRC_HUMAN 1 1261.7183 0.88 17084 17599 3 1261.718548 421.58 "Arginine--tRNA ligase, cytoplasmic OS=Homo sapiens OX=9606 GN=RARS1 PE=1 SV=2" 6.07 3214.2 - 997388 - - - 0.1863 - 2.583 0.34 - 322.6 1 2 0 0.0002 11 0 0 0 3.99E+07 4.52E+07 - - - 5.0264 0.9985 221125_WJC_METTL3_EV_vs_WT_F02.17601.17601.2 6.14E-07 13/30 K.TVEGAGSIAAATGFVK[136.11].K "sp|P37840|SYUA_HUMAN,tr|A0A669KB41|A0A669KB41_HUMAN,tr|A0A669KBH5|A0A669KBH5_HUMAN,tr|H6UYS7|H6UYS7_HUMAN,tr|E7EPV7|E7EPV7_HUMAN" 5 1485.7919 2.95 17086 17601 2 1485.799059 743.9032 Alpha-synuclein OS=Homo sapiens OX=9606 GN=SNCA PE=1 SV=1 5.66 3214.5 - 552956 - - - 4.8459 - 2.646 0.573 - 308.3 1 2 0 0.0072 16 0 0 0 1.61E+07 5.46E+06 - - - 5.6632 0.9999 221125_WJC_METTL3_EV_vs_WT_F02.17602.17602.3 0.00101 Sep-40 R.VFIPHGLIMDR[166.11].T sp|P00492|HPRT_HUMAN 1 1306.7095 1.22 17087 17602 3 1306.711026 436.5771 Hypoxanthine-guanine phosphoribosyltransferase OS=Homo sapiens OX=9606 GN=HPRT1 PE=1 SV=2 6.71 3214.6 - 401542 - - - 1.1426 - 2.06 0.429 - 117 1 2 0 0.0015 11 0 0 0 4.29E+07 3.53E+07 - - - 5.3756 1 221125_WJC_METTL3_EV_vs_WT_F02.17605.17605.2 7.39E-05 13/24 K.LPETNLFETEETR[166.11].K sp|Q15046|SYK_HUMAN 1 1587.7656 1 17090 17605 2 1587.762674 794.8901 Lysine--tRNA ligase OS=Homo sapiens OX=9606 GN=KARS1 PE=1 SV=3 4.09 3215 - 270112 - - - -1.8347 - 2.928 0.551 - 735.1 1 2 0 -0.0029 13 0 0 0 7.56E+06 7.59E+06 - - - 5.867 0.9994 221125_WJC_METTL3_EV_vs_WT_F02.17606.17606.2 0.000431 26-Aug R.LFPPDDSPLPVSSR[166.11].V "sp|Q05519|SRS11_HUMAN,tr|Q5T760|Q5T760_HUMAN,tr|B4DWT1|B4DWT1_HUMAN" 3 1535.7859 1.72 17091 17606 2 1535.787799 768.9002 Serine\arginine-rich splicing factor 11 OS=Homo sapiens OX=9606 GN=SRSF11 PE=1 SV=1 4.21 3215.1 - 260152 - - - 1.2176 - 1.642 0.398 - 96.6 1 2 0 0.0019 14 0 0 0 2.35E+07 1.36E+07 - - - 3.2245 1 221125_WJC_METTL3_EV_vs_WT_F02.17608.17608.2 8.45E-10 14/28 R.WFQPVANAADAEAVR[166.11].G "sp|O14654|IRS4_HUMAN,tr|A0A804CF45|A0A804CF45_HUMAN" 2 1653.8139 1.15 17093 17608 2 1653.811442 827.9142 Insulin receptor substrate 4 OS=Homo sapiens OX=9606 GN=IRS4 PE=1 SV=1 4.37 3215.4 - 172821 - - - -1.4711 - 2.417 0.662 - 544 1 2 0 -0.0024 15 0 0 0 1.20E+08 1.04E+08 - - - 6.0995 0.9968 221125_WJC_METTL3_EV_vs_WT_F02.17611.17611.2 0.0773 20-Aug K.FLEEQEITDLK[136.11].V sp|O60825|F262_HUMAN 1 1371.7013 3.59 17095 17611 2 1371.700171 686.8579 "6-phosphofructo-2-kinase\fructose-2,6-bisphosphatase 2 OS=Homo sapiens OX=9606 GN=PFKFB2 PE=1 SV=2" 4 3215.8 - 465816 - - - -0.8318 - 1.547 0.176 - 81.4 1 2 0 -0.0011 11 0 0 0 5.31E+07 1.48E+07 - - - 1.5209 0.9992 221125_WJC_METTL3_EV_vs_WT_F02.17613.17613.2 0.00153 16-Sep K.NLGFQMLQK.M "sp|Q8IX01|SUGP2_HUMAN,tr|M0R2Z9|M0R2Z9_HUMAN" 2 1077.5641 0.86 17097 17613 2 1077.564 539.7893 SURP and G-patch domain-containing protein 2 OS=Homo sapiens OX=9606 GN=SUGP2 PE=1 SV=2 8.75 3216 - 1.19E+06 - - - -0.0937 - 1.723 0.27 - 218.3 1 2 0 -0.0001 9 0 0 0 1.73E+07 2.03E+07 - - - 2.6092 0.9853 221125_WJC_METTL3_EV_vs_WT_F02.17617.17617.2 0.000805 12-Aug D.GDFVVLK.R sp|Q9UJA5|TRM6_HUMAN 1 776.4432 0.69 17101 17617 2 776.442473 389.2289 tRNA (adenine(58)-N(1))-methyltransferase non-catalytic subunit TRM6 OS=Homo sapiens OX=9606 GN=TRMT6 PE=1 SV=1 5.84 3216.4 - 523911 - - - -0.9878 - 1.747 0.436 - 305.2 1 1 0 -0.0008 7 0 0 0 5.42E+07 7.82E+07 - - - 4.0288 1 221125_WJC_METTL3_EV_vs_WT_F02.17618.17618.2 7.33E-11 14/28 R.WFQPVANAADAEAVR.G "sp|O14654|IRS4_HUMAN,tr|A0A804CF45|A0A804CF45_HUMAN" 2 1643.8056 1.15 17102 17618 2 1643.805935 822.9101 Insulin receptor substrate 4 OS=Homo sapiens OX=9606 GN=IRS4 PE=1 SV=1 4.37 3216.5 - 510462 - - - 0.2008 - 2.753 0.63 - 481.8 1 2 0 0.0003 15 0 0 0 1.20E+08 1.04E+08 - - - 6.1838 0.9991 221125_WJC_METTL3_EV_vs_WT_F02.17619.17619.2 3.22E-05 15/24 K.VLATAFDTTLGGR[166.11].K "sp|P34932|HSP74_HUMAN,tr|A0A087WTS8|A0A087WTS8_HUMAN,tr|A0A087WYC1|A0A087WYC1_HUMAN" 3 1330.712 0.08 17103 17619 2 1330.717191 666.3633 Heat shock 70 kDa protein 4 OS=Homo sapiens OX=9606 GN=HSPA4 PE=1 SV=4 5.81 3216.6 - 447254 - - - 3.8746 - 2.525 0.497 - 834.4 1 2 0 0.0052 13 0 0 0 2.84E+07 3.48E+08 - - - 5.0874 0.9965 221125_WJC_METTL3_EV_vs_WT_F02.17620.17620.3 0.135 Sep-40 R.VFIPHGLIMDR.T sp|P00492|HPRT_HUMAN 1 1296.7013 0.86 17104 17620 3 1296.703715 433.241 Hypoxanthine-guanine phosphoribosyltransferase OS=Homo sapiens OX=9606 GN=HPRT1 PE=1 SV=2 6.71 3216.7 - 377329 - - - 1.891 - 1.754 0.243 - 106.5 1 2 0 0.0025 11 0 0 0 3.01E+07 3.50E+07 - - - 2.8448 1 221125_WJC_METTL3_EV_vs_WT_F02.17622.17622.2 1.00E-09 14/22 K.TPYTDVNIVTIR.E "sp|P50213|IDH3A_HUMAN,tr|H0YLI6|H0YLI6_HUMAN,tr|H0YKD0|H0YKD0_HUMAN,tr|H0YL72|H0YL72_HUMAN,tr|H0YMU3|H0YMU3_HUMAN" 5 1390.7456 1.17 17105 17622 2 1390.74616 696.3801 "Isocitrate dehydrogenase [NAD] subunit alpha, mitochondrial OS=Homo sapiens OX=9606 GN=IDH3A PE=1 SV=1" 5.5 3217 - 3.30E+06 - - - 0.3811 - 2.713 0.562 - 653.9 1 2 0 0.0005 12 0 0 0 3.12E+07 2.66E+07 - - - 5.8178 0.9676 221125_WJC_METTL3_EV_vs_WT_F02.17624.17624.2 0.0164 18-Sep R.QVEEEILALK.A sp|Q15149|PLEC_HUMAN 1 1170.6496 1.95 17107 17624 2 1170.643449 586.3321 Plectin OS=Homo sapiens OX=9606 GN=PLEC PE=1 SV=3 4.25 3217.2 - 970603 - - - -5.2578 - 1.528 0.248 - 162.4 1 2 0 -0.0062 10 0 0 0 2.27E+07 1.16E+07 - - - 2.0542 0.999 221125_WJC_METTL3_EV_vs_WT_F02.17627.17627.3 0.00127 Sep-44 K.TPYTDVNIVTIR[166.11].E "sp|P50213|IDH3A_HUMAN,tr|H0YLI6|H0YLI6_HUMAN,tr|H0YKD0|H0YKD0_HUMAN,tr|H0YL72|H0YL72_HUMAN,tr|H0YMU3|H0YMU3_HUMAN" 5 1400.7539 0.98 17110 17627 3 1400.754188 467.9252 "Isocitrate dehydrogenase [NAD] subunit alpha, mitochondrial OS=Homo sapiens OX=9606 GN=IDH3A PE=1 SV=1" 5.5 3217.5 - 269513 - - - 0.2056 - 1.611 0.31 - 76.2 1 2 0 0.0003 12 0 0 0 3.48E+06 3.56E+06 - - - 3.3179 1 221125_WJC_METTL3_EV_vs_WT_F02.17631.17631.2 1.43E-08 20-Nov M.PMFIVNTNVPR[166.11].A sp|P14174|MIF_HUMAN 1 1296.6888 1.19 17113 17631 2 1296.69023 649.3517 Macrophage migration inhibitory factor OS=Homo sapiens OX=9606 GN=MIF PE=1 SV=4 10.18 3217.8 - 3.58E+06 - - - 1.1051 - 2.567 0.57 - 539.6 1 2 0 0.0014 11 0 0 0 3.23E+08 2.71E+08 - - - 5.8009 0.997 221125_WJC_METTL3_EV_vs_WT_F02.17632.17632.2 0.038 16-Jul K.NLGFQMLQK[136.11].M "sp|Q8IX01|SUGP2_HUMAN,tr|M0R2Z9|M0R2Z9_HUMAN" 2 1085.5783 0.84 17114 17632 2 1085.579723 543.7964 SURP and G-patch domain-containing protein 2 OS=Homo sapiens OX=9606 GN=SUGP2 PE=1 SV=2 8.75 3217.9 - 1.92E+06 - - - 1.3099 - 1.375 0.25 - 114.9 1 2 0 0.0014 9 0 0 0 1.79E+07 2.14E+07 - - - 1.8084 0.9907 221125_WJC_METTL3_EV_vs_WT_F02.17633.17633.2 0.000113 22-Oct R.INFYC[160.03]PGSALGR[166.11].N sp|Q9Y5B9|SP16H_HUMAN 1 1363.6582 0.19 17115 17633 2 1363.648832 682.8364 FACT complex subunit SPT16 OS=Homo sapiens OX=9606 GN=SUPT16H PE=1 SV=1 8.22 3218 - 859102 - - - -6.8888 - 2.148 0.493 - 380.5 1 2 0 -0.0094 12 0 0 0 1.62E+07 8.35E+07 - - - 4.691 1 221125_WJC_METTL3_EV_vs_WT_F02.17640.17640.2 1.60E-06 13/20 M.PMFIVNTNVPR.A sp|P14174|MIF_HUMAN 1 1286.6805 1.19 17120 17640 2 1286.68336 644.3475 Macrophage migration inhibitory factor OS=Homo sapiens OX=9606 GN=MIF PE=1 SV=4 10.18 3218.9 - 4.32E+06 - - - 2.2018 - 2.831 0.587 - 870.2 1 2 0 0.0028 11 0 0 0 3.23E+08 2.71E+08 - - - 6.1908 1 221125_WJC_METTL3_EV_vs_WT_F02.17642.17642.3 1.05E-05 18/56 R.WFQPVANAADAEAVR[166.11].G "sp|O14654|IRS4_HUMAN,tr|A0A804CF45|A0A804CF45_HUMAN" 2 1653.8139 1.11 17122 17642 3 1653.81416 552.2786 Insulin receptor substrate 4 OS=Homo sapiens OX=9606 GN=IRS4 PE=1 SV=1 4.37 3219.1 - 1.16E+06 - - - 0.1723 - 3.244 0.525 - 543.4 1 2 0 0.0003 15 0 0 0 3.72E+07 3.35E+07 - - - 7.4639 0.9997 221125_WJC_METTL3_EV_vs_WT_F02.17643.17643.2 0.0171 20-Nov K.LLLIGDSGVGK.T "sp|P61006|RAB8A_HUMAN,sp|P51153|RAB13_HUMAN,sp|P61026|RAB10_HUMAN,sp|Q15286|RAB35_HUMAN,sp|Q9H0U4|RAB1B_HUMAN,sp|P59190|RAB15_HUMAN,sp|P62820|RAB1A_HUMAN,sp|Q92930|RAB8B_HUMAN,sp|Q92928|RAB1C_HUMAN,tr|H0YMN7|H0YMN7_HUMAN,tr|H0YL94|H0YL94_HUMAN,tr|A0A2R8YDI9|A0A2R8YDI9_HUMAN,tr|H0YNE9|H0YNE9_HUMAN,tr|G3V196|G3V196_HUMAN,tr|A0A2R8YFB8|A0A2R8YFB8_HUMAN,tr|H0YLJ8|H0YLJ8_HUMAN,tr|E9PLD0|E9PLD0_HUMAN,tr|E7END7|E7END7_HUMAN,tr|F5H157|F5H157_HUMAN" 19 1070.6336 1.15 17123 17643 2 1070.633841 536.3241 Ras-related protein Rab-8A OS=Homo sapiens OX=9606 GN=RAB8A PE=1 SV=1 5.84 3219.2 - 983930 - - - 0.2625 - 2.112 0.355 - 329.7 1 2 0 0.0003 11 0 0 0 4.02E+08 3.50E+08 - - - 3.6855 1 221125_WJC_METTL3_EV_vs_WT_F02.17644.17644.3 5.80E-12 22/56 R.WFQPVANAADAEAVR.G "sp|O14654|IRS4_HUMAN,tr|A0A804CF45|A0A804CF45_HUMAN" 2 1643.8056 1.11 17124 17644 3 1643.809684 548.9425 Insulin receptor substrate 4 OS=Homo sapiens OX=9606 GN=IRS4 PE=1 SV=1 4.37 3219.3 - 964442 - - - 2.4814 - 3.664 0.541 - 566.9 1 2 0 0.0041 15 0 0 0 3.72E+07 3.35E+07 - - - 7.9589 0.9999 221125_WJC_METTL3_EV_vs_WT_F02.17645.17645.3 0.00745 15/36 K.FAEAFEAIPR.A sp|P50990|TCPQ_HUMAN 1 1149.5819 0.37 17125 17645 3 1149.581755 384.2012 T-complex protein 1 subunit theta OS=Homo sapiens OX=9606 GN=CCT8 PE=1 SV=4 4.53 3219.4 - 592373 - - - -0.0905 - 2.027 0.44 - 383.1 1 2 0 -0.0001 10 0 0 0 7.04E+06 1.88E+07 - - - 5.509 0.9998 221125_WJC_METTL3_EV_vs_WT_F02.17646.17646.2 4.10E-05 22-Nov R.VVVDSDSLAFVK.G sp|Q86U28|ISCA2_HUMAN 1 1277.6867 3.32 17126 17646 2 1277.684594 639.8506 "Iron-sulfur cluster assembly 2 homolog, mitochondrial OS=Homo sapiens OX=9606 GN=ISCA2 PE=1 SV=2" 4.21 3219.6 - 574828 - - - -1.6624 - 2.168 0.493 - 279.8 1 2 0 -0.0021 12 0 0 0 2.48E+07 7.47E+06 - - - 4.7176 0.988 221125_WJC_METTL3_EV_vs_WT_F02.17647.17647.2 0.000212 22-Dec N.SVLLVSNLNPER.V "sp|P26599|PTBP1_HUMAN,tr|A0A0U1RRM4|A0A0U1RRM4_HUMAN,tr|A6NLN1|A6NLN1_HUMAN,tr|A0A7I2V621|A0A7I2V621_HUMAN,tr|K7EK45|K7EK45_HUMAN" 5 1339.746 0.89 17127 17647 2 1339.748342 670.8803 Polypyrimidine tract-binding protein 1 OS=Homo sapiens OX=9606 GN=PTBP1 PE=1 SV=1 5.72 3219.6 - 502220 - - - 1.7742 - 2.617 0.493 - 682.2 1 1 0 0.0024 12 0 0 0 7.83E+06 8.79E+06 - - - 5.2128 0.9452 221125_WJC_METTL3_EV_vs_WT_F02.17649.17649.2 4.35 12-Jul K.SSFSIWR[166.11].H sp|Q9ULJ3|ZBT21_HUMAN 1 891.4478 1.49 17129 17649 2 891.451036 446.7312 Zinc finger and BTB domain-containing protein 21 OS=Homo sapiens OX=9606 GN=ZBTB21 PE=1 SV=2 9.47 3219.9 - 409160 - - - 3.6054 - 1.307 0.119 - 140.4 1 2 0 0.0032 7 0 0 0 1.69E+07 1.13E+07 - - - 0.7673 0.9864 221125_WJC_METTL3_EV_vs_WT_F02.17651.17651.2 0.00489 12-Aug D.GDFVVLK[136.11].R sp|Q9UJA5|TRM6_HUMAN 1 784.4574 0.69 17130 17651 2 784.456883 393.236 tRNA (adenine(58)-N(1))-methyltransferase non-catalytic subunit TRM6 OS=Homo sapiens OX=9606 GN=TRMT6 PE=1 SV=1 5.84 3220.1 - 4.12E+06 - - - -0.71 - 1.781 0.424 - 341.1 1 1 0 -0.0006 7 0 0 0 5.43E+07 7.82E+07 - - - 4.0013 0.9994 221125_WJC_METTL3_EV_vs_WT_F02.17652.17652.2 0.00129 16-Sep K.AAALEFLNR.F "sp|P31948|STIP1_HUMAN,tr|F5GXD8|F5GXD8_HUMAN,tr|F5H783|F5H783_HUMAN" 3 1003.5451 0.6 17131 17652 2 1003.543588 502.7798 Stress-induced-phosphoprotein 1 OS=Homo sapiens OX=9606 GN=STIP1 PE=1 SV=1 6.05 3220.2 - 858557 - - - -1.4867 - 1.91 0.319 - 249.4 1 2 0 -0.0015 9 0 0 0 2.62E+07 4.39E+07 - - - 3.2688 0.9998 221125_WJC_METTL3_EV_vs_WT_F02.17653.17653.2 5.45 20-Dec K.LLLIGDSGVGK[136.11].T "sp|P61006|RAB8A_HUMAN,sp|P51153|RAB13_HUMAN,sp|P61026|RAB10_HUMAN,sp|Q15286|RAB35_HUMAN,sp|Q9H0U4|RAB1B_HUMAN,sp|P59190|RAB15_HUMAN,sp|P62820|RAB1A_HUMAN,sp|Q92930|RAB8B_HUMAN,sp|Q92928|RAB1C_HUMAN,tr|H0YMN7|H0YMN7_HUMAN,tr|H0YL94|H0YL94_HUMAN,tr|A0A2R8YDI9|A0A2R8YDI9_HUMAN,tr|H0YNE9|H0YNE9_HUMAN,tr|G3V196|G3V196_HUMAN,tr|A0A2R8YFB8|A0A2R8YFB8_HUMAN,tr|H0YLJ8|H0YLJ8_HUMAN,tr|E9PLD0|E9PLD0_HUMAN,tr|E7END7|E7END7_HUMAN,tr|F5H157|F5H157_HUMAN" 19 1078.6478 1.15 17132 17653 2 1078.647871 540.3312 Ras-related protein Rab-8A OS=Homo sapiens OX=9606 GN=RAB8A PE=1 SV=1 5.84 3220.2 - 2.94E+06 - - - 0.1029 - 2.468 0.398 - 411.3 1 2 0 0.0001 11 0 0 0 4.02E+08 3.50E+08 - - - 4.4245 0.9971 221125_WJC_METTL3_EV_vs_WT_F02.17656.17656.2 0.00832 20-Jul R.LSFYETGEIPR[166.11].K "sp|O00567|NOP56_HUMAN,tr|A0A494C128|A0A494C128_HUMAN,tr|H0YDU4|H0YDU4_HUMAN,tr|H0Y653|H0Y653_HUMAN" 4 1320.6589 23.08 17135 17656 2 1320.661951 661.3367 Nucleolar protein 56 OS=Homo sapiens OX=9606 GN=NOP56 PE=1 SV=4 4.53 3220.5 - 798888 - - - 2.2822 - 1.658 0.259 - 118.9 1 2 0 0.003 11 0 0 0 1.36E+08 5.88E+06 - - - 2.3208 0.9998 221125_WJC_METTL3_EV_vs_WT_F02.17658.17658.2 4.77E-07 20-Aug R.ADQFEYVMYGK[136.11].V "sp|P52434|RPAB3_HUMAN,tr|C9JLU1|C9JLU1_HUMAN" 2 1357.6104 0.96 17137 17658 2 1357.608204 679.8125 "DNA-directed RNA polymerases I, II, and III subunit RPABC3 OS=Homo sapiens OX=9606 GN=POLR2H PE=1 SV=4" 4.37 3220.8 - 537612 - - - -1.6094 - 1.975 0.506 - 279.6 1 2 0 -0.0022 11 0 0 0 2.07E+07 2.15E+07 - - - 4.6187 0.9666 221125_WJC_METTL3_EV_vs_WT_F02.17663.17663.2 1.42 18-Sep K.IQQGALELLR.S "sp|Q92621|NU205_HUMAN,tr|U3KPX2|U3KPX2_HUMAN" 2 1139.6663 3.02 17140 17663 2 1139.671398 570.8404 Nuclear pore complex protein Nup205 OS=Homo sapiens OX=9606 GN=NUP205 PE=1 SV=3 6 3221.5 - 1.17E+06 - - - 4.5101 - 1.658 0.159 - 215.9 1 2 0 0.0051 10 0 0 0 1.98E+07 6.57E+06 - - - 1.6251 0.9989 221125_WJC_METTL3_EV_vs_WT_F02.17664.17664.2 5.85E-05 20-Nov R.LSFYETGEIPR.K "sp|O00567|NOP56_HUMAN,tr|A0A494C128|A0A494C128_HUMAN,tr|H0YDU4|H0YDU4_HUMAN,tr|H0Y653|H0Y653_HUMAN" 4 1310.6507 48.43 17141 17664 2 1310.655499 656.3326 Nucleolar protein 56 OS=Homo sapiens OX=9606 GN=NOP56 PE=1 SV=4 4.53 3221.6 - 1.06E+06 - - - 3.6867 - 2.197 0.452 - 397.9 1 2 0 0.0048 11 0 0 0 2.85E+08 5.88E+06 - - - 4.5072 0.9991 221125_WJC_METTL3_EV_vs_WT_F02.17665.17665.2 0.00241 18-Sep R.QVEEEILALK[136.11].A sp|Q15149|PLEC_HUMAN 1 1178.6638 2.34 17142 17665 2 1178.66151 590.3392 Plectin OS=Homo sapiens OX=9606 GN=PLEC PE=1 SV=3 4.25 3221.7 - 933547 - - - -1.9463 - 1.8 0.336 - 255.8 1 2 0 -0.0023 10 0 0 0 2.74E+07 1.17E+07 - - - 3.1627 0.9976 221125_WJC_METTL3_EV_vs_WT_F02.17666.17666.2 0.00227 18-Aug R.DMTMFVTASK.D "sp|Q13347|EIF3I_HUMAN,tr|A0A7I2YQT9|A0A7I2YQT9_HUMAN,tr|A0A7I2V613|A0A7I2V613_HUMAN,tr|A0A7I2V3N2|A0A7I2V3N2_HUMAN,tr|A0A7I2YQU2|A0A7I2YQU2_HUMAN,tr|A0A7I2YQI6|A0A7I2YQI6_HUMAN,tr|A0A7I2YQF8|A0A7I2YQF8_HUMAN,tr|Q5TFK1|Q5TFK1_HUMAN,tr|A0A7I2V3U3|A0A7I2V3U3_HUMAN,tr|A0A7I2V607|A0A7I2V607_HUMAN,tr|A0A7I2V640|A0A7I2V640_HUMAN,tr|A0A7P0MRT9|A0A7P0MRT9_HUMAN,tr|A0A7I2V3K6|A0A7I2V3K6_HUMAN,tr|A0A7I2V4S8|A0A7I2V4S8_HUMAN,tr|A0A7I2V5V8|A0A7I2V5V8_HUMAN,tr|A0A7I2V2M3|A0A7I2V2M3_HUMAN,tr|A0A7I2V4C2|A0A7I2V4C2_HUMAN,tr|A0A7I2YQP9|A0A7I2YQP9_HUMAN,tr|A0A7I2YQI2|A0A7I2YQI2_HUMAN,tr|A0A7I2YQC8|A0A7I2YQC8_HUMAN,tr|A0A7I2V685|A0A7I2V685_HUMAN" 21 1129.5148 1.09 17143 17666 2 1129.510576 565.7647 Eukaryotic translation initiation factor 3 subunit I OS=Homo sapiens OX=9606 GN=EIF3I PE=1 SV=1 5.84 3221.7 - 910226 - - - -3.7104 - 1.659 0.416 - 226.4 1 2 0 -0.0042 10 0 0 0 6.80E+07 6.27E+07 - - - 3.5253 0.965 221125_WJC_METTL3_EV_vs_WT_F02.17667.17667.2 0.0102 16-Aug K.VHAELADVL.T "sp|Q92526|TCPW_HUMAN,sp|P40227|TCPZ_HUMAN,tr|J3KRI6|J3KRI6_HUMAN" 3 965.5182 - 17144 17667 2 965.51819 483.7664 T-complex protein 1 subunit zeta-2 OS=Homo sapiens OX=9606 GN=CCT6B PE=1 SV=5 4.35 3221.9 - 839545 - - - -0.0062 - 1.594 0.331 - 165.1 1 1 0 0 9 0 0 0 - - - - - 2.8346 0.9998 221125_WJC_METTL3_EV_vs_WT_F02.17673.17673.2 0.00357 18-Sep R.DMTMFVTASK[136.11].D "sp|Q13347|EIF3I_HUMAN,tr|A0A7I2YQT9|A0A7I2YQT9_HUMAN,tr|A0A7I2V613|A0A7I2V613_HUMAN,tr|A0A7I2V3N2|A0A7I2V3N2_HUMAN,tr|A0A7I2YQU2|A0A7I2YQU2_HUMAN,tr|A0A7I2YQI6|A0A7I2YQI6_HUMAN,tr|A0A7I2YQF8|A0A7I2YQF8_HUMAN,tr|Q5TFK1|Q5TFK1_HUMAN,tr|A0A7I2V3U3|A0A7I2V3U3_HUMAN,tr|A0A7I2V607|A0A7I2V607_HUMAN,tr|A0A7I2V640|A0A7I2V640_HUMAN,tr|A0A7P0MRT9|A0A7P0MRT9_HUMAN,tr|A0A7I2V3K6|A0A7I2V3K6_HUMAN,tr|A0A7I2V4S8|A0A7I2V4S8_HUMAN,tr|A0A7I2V5V8|A0A7I2V5V8_HUMAN,tr|A0A7I2V2M3|A0A7I2V2M3_HUMAN,tr|A0A7I2V4C2|A0A7I2V4C2_HUMAN,tr|A0A7I2YQP9|A0A7I2YQP9_HUMAN,tr|A0A7I2YQI2|A0A7I2YQI2_HUMAN,tr|A0A7I2YQC8|A0A7I2YQC8_HUMAN,tr|A0A7I2V685|A0A7I2V685_HUMAN" 21 1137.529 1.09 17148 17673 2 1137.529413 569.7718 Eukaryotic translation initiation factor 3 subunit I OS=Homo sapiens OX=9606 GN=EIF3I PE=1 SV=1 5.84 3222.6 - 2.04E+06 - - - 0.3921 - 1.946 0.492 - 301.2 1 2 0 0.0004 10 0 0 0 6.80E+07 6.27E+07 - - - 4.5332 1 221125_WJC_METTL3_EV_vs_WT_F02.17676.17676.2 5.49E-07 20-Dec R.ADQFEYVMYGK.V "sp|P52434|RPAB3_HUMAN,tr|C9JLU1|C9JLU1_HUMAN" 2 1349.5962 0.96 17151 17676 2 1349.594027 675.8054 "DNA-directed RNA polymerases I, II, and III subunit RPABC3 OS=Homo sapiens OX=9606 GN=POLR2H PE=1 SV=4" 4.37 3222.8 - 1.58E+06 - - - -1.602 - 2.43 0.594 - 737.9 1 2 0 -0.0022 11 0 0 0 2.07E+07 2.15E+07 - - - 5.8296 0.9996 221125_WJC_METTL3_EV_vs_WT_F02.17677.17677.3 0.00046 Dec-48 K.VLATAFDTTLGGR[166.11].K "sp|P34932|HSP74_HUMAN,tr|A0A087WTS8|A0A087WTS8_HUMAN,tr|A0A087WYC1|A0A087WYC1_HUMAN" 3 1330.712 0.15 17152 17677 3 1330.712142 444.578 Heat shock 70 kDa protein 4 OS=Homo sapiens OX=9606 GN=HSPA4 PE=1 SV=4 5.81 3222.9 - 1.42E+06 - - - 0.0804 - 1.977 0.317 - 207.7 1 2 0 0.0001 13 0 0 0 2.24E+06 1.47E+07 - - - 3.9222 0.9998 221125_WJC_METTL3_EV_vs_WT_F02.17678.17678.3 0.000306 Oct-40 M.PMFIVNTNVPR.A sp|P14174|MIF_HUMAN 1 1286.6805 0.44 17153 17678 3 1286.68059 429.9008 Macrophage migration inhibitory factor OS=Homo sapiens OX=9606 GN=MIF PE=1 SV=4 10.18 3223 - 642761 - - - 0.049 - 2.108 0.341 - 202.6 1 2 0 0.0001 11 0 0 0 1.25E+07 2.87E+07 - - - 4.4603 0.9999 221125_WJC_METTL3_EV_vs_WT_F02.17681.17681.2 2.91E-06 14/28 R.LLEPGSLGGIPSPAK.S sp|Q9Y584|TIM22_HUMAN 1 1434.8082 2.08 17156 17681 2 1434.807456 718.4114 Mitochondrial import inner membrane translocase subunit Tim22 OS=Homo sapiens OX=9606 GN=TIMM22 PE=1 SV=2 6 3223.4 - 576843 - - - -0.5394 - 2.456 0.517 - 602.7 1 2 0 -0.0008 15 0 0 0 1.48E+07 7.13E+06 - - - 5.0684 0.9916 221125_WJC_METTL3_EV_vs_WT_F02.17682.17682.2 0.000608 22-Jul R.LYSEDELPAEFK.L sp|Q9Y6A4|CFA20_HUMAN 1 1439.682 1.19 17157 17682 2 1439.674107 720.8483 Cilia- and flagella-associated protein 20 OS=Homo sapiens OX=9606 GN=CFAP20 PE=1 SV=1 4 3223.6 - 552396 - - - -5.5012 - 1.755 0.409 - 105.4 1 2 0 -0.0079 12 0 0 0 2.11E+07 1.78E+07 - - - 3.5393 0.9999 221125_WJC_METTL3_EV_vs_WT_F02.17687.17687.2 3.90E-06 22-Nov K.IFDIDEAEEGVK[136.11].D sp|P20042|IF2B_HUMAN 1 1371.6649 1.08 17160 17687 2 1371.663119 686.8397 Eukaryotic translation initiation factor 2 subunit 2 OS=Homo sapiens OX=9606 GN=EIF2S2 PE=1 SV=2 3.83 3224.1 - 2.78E+06 - - - -1.3181 - 2.448 0.504 - 381.5 1 2 0 -0.0018 12 0 0 0 9.10E+07 8.39E+07 - - - 5.1186 0.9891 221125_WJC_METTL3_EV_vs_WT_F02.17688.17688.2 0.00629 20-Dec E.ILELLNTTTAK[136.11].E "sp|Q86U44|MTA70_HUMAN,tr|H0YFV6|H0YFV6_HUMAN" 2 1223.7217 0.001 17161 17688 2 1223.722186 612.8681 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 6 3224.1 - 2.11E+06 - - - 0.4347 - 2.52 0.374 - 350.5 1 1 0 0.0005 11 0 0 0 0.00E+00 4.66E+07 - - - 4.3035 1 221125_WJC_METTL3_EV_vs_WT_F02.17690.17690.2 9.52E-09 13/26 R.FGQGSGPIVLDDVR.C "sp|Q9UGM3|DMBT1_HUMAN,sp|Q9UGM3|DMBT1_HUMAN,sp|Q9UGM3|DMBT1_HUMAN,tr|A0A590UK99|A0A590UK99_HUMAN,tr|A0A590UJF8|A0A590UJF8_HUMAN,tr|A0A590UJZ9|A0A590UJZ9_HUMAN,tr|A0A590UJZ9|A0A590UJZ9_HUMAN,tr|A0A590UJ76|A0A590UJ76_HUMAN,tr|A0A590UJ76|A0A590UJ76_HUMAN,tr|A0A590UJ76|A0A590UJ76_HUMAN,tr|A0A590UIX5|A0A590UIX5_HUMAN" 11 1458.7467 999 17163 17690 2 1458.744642 730.3806 Deleted in malignant brain tumors 1 protein OS=Homo sapiens OX=9606 GN=DMBT1 PE=1 SV=2 4.21 3224.4 - 926639 - - - -1.406 - 2.744 0.566 - 569.7 1 2 0 -0.0021 14 0 0 0 7.16E+07 0.00E+00 - - - 5.7539 0.9989 221125_WJC_METTL3_EV_vs_WT_F02.17691.17691.2 9.62E-05 22-Oct K.VVVVVPNEEDWK[136.11].K "sp|Q1KMD3|HNRL2_HUMAN,tr|H3BQZ7|H3BQZ7_HUMAN" 2 1419.7489 1.62 17164 17691 2 1419.753919 710.8817 Heterogeneous nuclear ribonucleoprotein U-like protein 2 OS=Homo sapiens OX=9606 GN=HNRNPUL2 PE=1 SV=1 4.14 3224.5 - 766691 - - - 3.5133 - 2.046 0.46 - 285 1 2 0 0.005 12 0 0 0 1.94E+07 1.20E+07 - - - 4.3206 0.9162 221125_WJC_METTL3_EV_vs_WT_F02.17692.17692.2 0.0758 14-Jul F.AFLWAGGR.A "sp|Q00839|HNRPU_HUMAN,tr|A0A1W2PQL0|A0A1W2PQL0_HUMAN,tr|A0A1W2PPL4|A0A1W2PPL4_HUMAN,tr|A0A1W2PQ74|A0A1W2PQ74_HUMAN,tr|Q5RI18|Q5RI18_HUMAN,tr|A0A1W2PP35|A0A1W2PP35_HUMAN,tr|A0A1W2PPS1|A0A1W2PPS1_HUMAN,tr|A0A1W2PPH7|A0A1W2PPH7_HUMAN,tr|A0A1W2PP34|A0A1W2PP34_HUMAN,tr|A0A1W2PRI6|A0A1W2PRI6_HUMAN,tr|A0A1X7SBS1|A0A1X7SBS1_HUMAN,tr|A0A1W2PNG3|A0A1W2PNG3_HUMAN" 12 876.4606 0.45 17165 17692 2 876.459613 439.2376 Heterogeneous nuclear ribonucleoprotein U OS=Homo sapiens OX=9606 GN=HNRNPU PE=1 SV=6 9.79 3224.6 - 539972 - - - -1.1512 - 1.538 0.255 - 183.6 1 1 0 -0.001 8 0 0 0 2.45E+06 5.46E+06 - - - 2.2224 0.9966 221125_WJC_METTL3_EV_vs_WT_F02.17693.17693.2 0.108 16-Jul R.DISLAALQR.H "sp|Q8IZD4|DCP1B_HUMAN,tr|B4DVJ6|B4DVJ6_HUMAN,tr|F5H4R4|F5H4R4_HUMAN" 3 985.5556 1.82 17166 17693 2 985.556733 493.7851 mRNA-decapping enzyme 1B OS=Homo sapiens OX=9606 GN=DCP1B PE=1 SV=2 5.84 3224.8 - 376831 - - - 1.105 - 1.375 0.225 - 124.9 1 2 0 0.0011 9 0 0 0 7.64E+06 4.19E+06 - - - 1.6238 0.9997 221125_WJC_METTL3_EV_vs_WT_F02.17697.17697.2 0.00639 16-Sep K.LDDLFVTGR[166.11].N sp|Q969L4|LSM10_HUMAN 1 1044.5479 1.04 17169 17697 2 1044.547278 523.2812 U7 snRNA-associated Sm-like protein LSm10 OS=Homo sapiens OX=9606 GN=LSM10 PE=1 SV=1 4.21 3225.2 - 340400 - - - -0.6242 - 2.079 0.332 - 185.6 1 2 0 -0.0007 9 0 0 0 1.04E+07 9.93E+06 - - - 3.6103 0.9998 221125_WJC_METTL3_EV_vs_WT_F02.17699.17699.2 5.03E-05 18-Nov K.FAAQELIEVK[136.11].R "sp|Q86U44|MTA70_HUMAN,tr|F5H6D8|F5H6D8_HUMAN,tr|H0YFV6|H0YFV6_HUMAN,tr|B4DTN4|B4DTN4_HUMAN" 4 1154.6427 0.03 17170 17699 2 1154.643677 578.3286 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 4.53 3225.4 - 5.32E+06 - - - 0.8678 - 2.12 0.464 - 328.2 1 2 0 0.001 10 0 0 0 2.86E+10 8.50E+11 - - - 4.5652 0.9961 221125_WJC_METTL3_EV_vs_WT_F02.17700.17700.2 0.0905 14-Sep R.MLEILEGK.G "sp|P78344|IF4G2_HUMAN,tr|H0Y3P2|H0Y3P2_HUMAN,tr|D3DQV9|D3DQV9_HUMAN" 3 931.5049 2.66 17171 17700 2 931.505089 466.7597 Eukaryotic translation initiation factor 4 gamma 2 OS=Homo sapiens OX=9606 GN=EIF4G2 PE=1 SV=1 4.53 3225.6 - 1.74E+06 - - - 0.2523 - 1.638 0.105 - 312.8 1 2 0 0.0002 8 0 0 0 4.65E+07 1.75E+07 - - - 1.3048 0.9993 221125_WJC_METTL3_EV_vs_WT_F02.17701.17701.2 0.00856 18-Aug K.NDIAINELMK[136.11].R "sp|P51665|PSMD7_HUMAN,tr|H3BNT7|H3BNT7_HUMAN,tr|H3BTM8|H3BTM8_HUMAN" 3 1167.6049 33.53 17172 17701 2 1167.605803 584.8097 26S proteasome non-ATPase regulatory subunit 7 OS=Homo sapiens OX=9606 GN=PSMD7 PE=1 SV=2 4.37 3225.6 - 1.29E+06 - - - 0.7657 - 1.67 0.333 - 207.1 1 2 0 0.0009 10 0 0 0 1.18E+09 3.53E+07 - - - 2.9317 0.9999 221125_WJC_METTL3_EV_vs_WT_F02.17702.17702.2 5.81E-05 22-Nov K.VFSLMDPNSPER.V "sp|Q7L5D6|GET4_HUMAN,tr|C9JPA8|C9JPA8_HUMAN,tr|C9JHN8|C9JHN8_HUMAN,tr|C9JY46|C9JY46_HUMAN" 4 1390.6551 2.13 17173 17702 2 1390.656538 696.3348 Golgi to ER traffic protein 4 homolog OS=Homo sapiens OX=9606 GN=GET4 PE=1 SV=1 4.37 3225.7 - 945586 - - - 1.0333 - 2.365 0.553 - 337.5 1 2 0 0.0014 12 0 0 0 1.79E+07 8.39E+06 - - - 5.3899 0.9998 221125_WJC_METTL3_EV_vs_WT_F02.17706.17706.2 0.0015 24-Nov R.LEEMFPDEVDTPR[166.11].D sp|Q2NL82|TSR1_HUMAN 1 1586.7162 0.71 17177 17706 2 1586.714266 794.3654 Pre-rRNA-processing protein TSR1 homolog OS=Homo sapiens OX=9606 GN=TSR1 PE=1 SV=1 3.83 3226.2 - 269495 - - - -1.2151 - 2.223 0.502 - 381.6 1 2 0 -0.0019 13 0 0 0 1.72E+06 2.41E+06 - - - 4.7985 0.9998 221125_WJC_METTL3_EV_vs_WT_F02.17707.17707.3 0.00849 Oct-36 R.LNVEFALIHK.E sp|P11908|PRPS2_HUMAN 1 1182.6761 1.39 17178 17707 3 1182.676807 395.2326 Ribose-phosphate pyrophosphokinase 2 OS=Homo sapiens OX=9606 GN=PRPS2 PE=1 SV=2 6.75 3226.3 - 247314 - - - 0.6029 - 1.747 0.415 - 94.2 1 2 0 0.0007 10 0 0 0 9.55E+06 6.85E+06 - - - 4.796 0.9999 221125_WJC_METTL3_EV_vs_WT_F02.17709.17709.2 1.84E-07 24-Oct K.LC[160.03]SLFYTNEEVAK.N "sp|P43243|MATR3_HUMAN,tr|B3KM87|B3KM87_HUMAN,tr|A8MXP9|A8MXP9_HUMAN,tr|A0A0R4J2E8|A0A0R4J2E8_HUMAN" 4 1572.7494 1.26 17179 17709 2 1572.75106 787.382 Matrin-3 OS=Homo sapiens OX=9606 GN=MATR3 PE=1 SV=2 4.53 3226.6 - 339020 - - - 1.0587 - 2.314 0.536 - 320.4 1 2 0 0.0017 13 0 0 0 6.90E+08 5.47E+08 - - - 5.1526 0.9998 221125_WJC_METTL3_EV_vs_WT_F02.17712.17712.2 1.93E-05 18-Oct K.TFEVC[160.03]DLPVR.A "sp|P35606|COPB2_HUMAN,tr|H0Y938|H0Y938_HUMAN,tr|A0A7I2V3G0|A0A7I2V3G0_HUMAN,tr|D6RBZ7|D6RBZ7_HUMAN,tr|D6R997|D6R997_HUMAN,tr|D6RBT6|D6RBT6_HUMAN,tr|H0YAC7|H0YAC7_HUMAN,tr|D6RBG7|D6RBG7_HUMAN,tr|A0A7I2YQF9|A0A7I2YQF9_HUMAN,tr|D6RCL6|D6RCL6_HUMAN" 10 1234.6016 1.01 17181 17712 2 1234.600476 618.3081 Coatomer subunit beta' OS=Homo sapiens OX=9606 GN=COPB2 PE=1 SV=2 4.37 3226.9 - 1.30E+06 - - - -0.9177 - 1.971 0.498 - 352.9 1 2 0 -0.0011 10 0 0 0 1.53E+07 1.52E+07 - - - 4.6129 0.9997 221125_WJC_METTL3_EV_vs_WT_F02.17713.17713.2 0.0184 20-Nov R.AFSDPFVEAEK.S "sp|P34932|HSP74_HUMAN,tr|A0A087WTS8|A0A087WTS8_HUMAN,tr|A0A087WYC1|A0A087WYC1_HUMAN" 3 1238.5819 0.06 17182 17713 2 1238.581841 620.2982 Heat shock 70 kDa protein 4 OS=Homo sapiens OX=9606 GN=HSPA4 PE=1 SV=4 4.14 3226.9 - 1.30E+06 - - - -0.063 - 1.942 0.379 - 302.8 1 2 0 -0.0001 11 0 0 0 4.80E+07 7.41E+08 - - - 3.6358 0.9997 221125_WJC_METTL3_EV_vs_WT_F02.17714.17714.2 0.00107 20-Nov K.DVTGAEALLER[166.11].H "sp|Q13813|SPTN1_HUMAN,tr|A0A0D9SF54|A0A0D9SF54_HUMAN,tr|A0A0D9SGF6|A0A0D9SGF6_HUMAN" 3 1182.612 3.07 17183 17714 2 1182.613863 592.3133 "Spectrin alpha chain, non-erythrocytic 1 OS=Homo sapiens OX=9606 GN=SPTAN1 PE=1 SV=3" 4.14 3227 - 1.19E+06 - - - 1.5863 - 2.238 0.419 - 416 1 2 0 0.0019 11 0 0 0 7.78E+07 2.53E+07 - - - 4.3144 0.9998 221125_WJC_METTL3_EV_vs_WT_F02.17717.17717.3 0.000146 Sep-36 R.LNVEFALIHK[136.11].E sp|P11908|PRPS2_HUMAN 1 1190.6903 1.39 17186 17717 3 1190.691944 397.904 Ribose-phosphate pyrophosphokinase 2 OS=Homo sapiens OX=9606 GN=PRPS2 PE=1 SV=2 6.75 3227.4 - 372388 - - - 1.3858 - 1.757 0.414 - 88.3 1 2 0 0.0016 10 0 0 0 9.55E+06 6.85E+06 - - - 4.8012 0.9997 221125_WJC_METTL3_EV_vs_WT_F02.17719.17719.2 0.000752 24-Jul K.LC[160.03]SLFYTNEEVAK[136.11].N "sp|P43243|MATR3_HUMAN,tr|B3KM87|B3KM87_HUMAN,tr|A8MXP9|A8MXP9_HUMAN,tr|A0A0R4J2E8|A0A0R4J2E8_HUMAN" 4 1580.7636 1.26 17187 17719 2 1580.764035 791.3891 Matrin-3 OS=Homo sapiens OX=9606 GN=MATR3 PE=1 SV=2 4.53 3227.6 - 298606 - - - 0.2783 - 1.538 0.446 - 129.2 1 2 0 0.0004 13 0 0 0 6.90E+08 5.47E+08 - - - 3.4399 0.9878 221125_WJC_METTL3_EV_vs_WT_F02.17721.17721.2 0.00292 18-Nov K.FAAQELIEVK.R "sp|Q86U44|MTA70_HUMAN,tr|F5H6D8|F5H6D8_HUMAN,tr|H0YFV6|H0YFV6_HUMAN,tr|B4DTN4|B4DTN4_HUMAN" 4 1146.6285 0.03 17188 17721 2 1147.630899 574.3215 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 4.53 3227.8 - 7.09E+06 - - - 874.2361 - 2.056 0.401 - 301.2 1 2 0 1.0024 10 0 0 0 2.86E+10 8.50E+11 - - - 3.6999 0.9998 221125_WJC_METTL3_EV_vs_WT_F02.17722.17722.3 0.0119 Dec-36 K.FAAQELIEVK[136.11].R "sp|Q86U44|MTA70_HUMAN,tr|F5H6D8|F5H6D8_HUMAN,tr|H0YFV6|H0YFV6_HUMAN,tr|B4DTN4|B4DTN4_HUMAN" 4 1154.6427 0.01 17189 17722 3 1154.640857 385.8882 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 4.53 3227.9 - 1.44E+06 - - - -1.5745 - 2.327 0.339 - 186.5 1 2 0 -0.0018 10 0 0 0 1.48E+07 2.40E+09 - - - 4.7856 0.9989 221125_WJC_METTL3_EV_vs_WT_F02.17723.17723.2 0.000837 16-Sep K.GYGFVEYMK.K sp|Q9HCJ3|RAVR2_HUMAN 1 1092.495 8.86 17190 17723 2 1092.492133 547.2548 Ribonucleoprotein PTB-binding 2 OS=Homo sapiens OX=9606 GN=RAVER2 PE=1 SV=2 6 3228 - 1.45E+06 - - - -2.6407 - 1.626 0.42 - 243.2 1 2 0 -0.0029 9 0 0 0 1.15E+08 1.30E+07 - - - 3.5486 0.9963 221125_WJC_METTL3_EV_vs_WT_F02.17727.17727.2 1.12E-05 22-Nov R.SVC[160.03]TEAGMFAIR[166.11].A "sp|P35998|PRS7_HUMAN,tr|C9JX88|C9JX88_HUMAN" 2 1350.63 0.4 17192 17727 2 1350.621884 676.3223 26S proteasome regulatory subunit 7 OS=Homo sapiens OX=9606 GN=PSMC2 PE=1 SV=3 5.72 3228.5 - 1.13E+06 - - - -5.9809 - 2.319 0.552 - 442.9 1 2 0 -0.0081 12 0 0 0 5.29E+06 1.32E+07 - - - 5.3287 0.9993 221125_WJC_METTL3_EV_vs_WT_F02.17730.17730.2 0.00231 16-Aug K.GYGFVEYMK[136.11].K sp|Q9HCJ3|RAVR2_HUMAN 1 1100.5092 8.08 17195 17730 2 1100.507849 551.2619 Ribonucleoprotein PTB-binding 2 OS=Homo sapiens OX=9606 GN=RAVER2 PE=1 SV=2 6 3228.8 - 1.60E+06 - - - -1.244 - 1.461 0.387 - 178.1 1 2 0 -0.0014 9 0 0 0 1.05E+08 1.30E+07 - - - 2.9958 0.9999 221125_WJC_METTL3_EV_vs_WT_F02.17732.17732.2 4.40E-06 13/22 R.GDGVVLVAPPLR.V sp|P62310|LSM3_HUMAN 1 1191.6976 3.59 17197 17732 2 1191.69698 596.8561 U6 snRNA-associated Sm-like protein LSm3 OS=Homo sapiens OX=9606 GN=LSM3 PE=1 SV=2 5.84 3229 - 944946 - - - -0.485 - 2.346 0.501 - 616.4 1 2 0 -0.0006 12 0 0 0 9.51E+08 2.65E+08 - - - 4.9848 0.9999 221125_WJC_METTL3_EV_vs_WT_F02.17734.17734.2 0.00022 13/20 K.EAEAAFLNVYK[136.11].R "sp|Q13948|CASP_HUMAN,sp|P39880|CUX1_HUMAN,tr|A0A2R8Y852|A0A2R8Y852_HUMAN,tr|A0A2R8YDI1|A0A2R8YDI1_HUMAN" 4 1261.6434 1.92 17199 17734 2 1261.642025 631.829 Protein CASP OS=Homo sapiens OX=9606 GN=CUX1 PE=1 SV=2 4.53 3229.3 - 728241 - - - -1.0922 - 2.558 0.456 - 786.2 1 2 0 -0.0014 11 0 0 0 9.03E+07 4.70E+07 - - - 4.9494 0.944 221125_WJC_METTL3_EV_vs_WT_F02.17738.17738.2 0.000163 22-Oct R.GLLQDDAHPTLV.T "sp|Q86U44|MTA70_HUMAN,tr|F5H6D8|F5H6D8_HUMAN,tr|H0YFV6|H0YFV6_HUMAN,tr|B4DTN4|B4DTN4_HUMAN" 4 1277.6616 - 17201 17738 2 1277.657028 639.8381 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 4.2 3229.8 - 1.38E+07 - - - -3.5518 - 1.987 0.499 - 238.3 1 1 0 -0.0045 12 0 0 0 - - - - - 4.5318 1 221125_WJC_METTL3_EV_vs_WT_F02.17744.17744.3 0.000433 17/56 R.LLIHQSLAGGIIGVK[136.11].G "sp|P61978|HNRPK_HUMAN,tr|Q5T6W2|Q5T6W2_HUMAN" 2 1525.9435 1.22 17205 17744 3 1525.943428 509.6551 Heterogeneous nuclear ribonucleoprotein K OS=Homo sapiens OX=9606 GN=HNRNPK PE=1 SV=1 8.76 3230.3 - 7.43E+06 - - - -0.0793 - 3.431 0.491 - 502.7 1 2 0 -0.0001 15 0 0 0 1.07E+09 8.80E+08 - - - 7.2311 1 221125_WJC_METTL3_EV_vs_WT_F02.17748.17748.3 4.20E-07 14/56 R.LLIHQSLAGGIIGVK.G "sp|P61978|HNRPK_HUMAN,tr|Q5T6W2|Q5T6W2_HUMAN" 2 1517.9293 1.22 17207 17748 3 1517.928826 506.9837 Heterogeneous nuclear ribonucleoprotein K OS=Homo sapiens OX=9606 GN=HNRNPK PE=1 SV=1 8.76 3230.8 - 8.41E+06 - - - -0.3445 - 3.094 0.491 - 183.5 1 2 0 -0.0005 15 0 0 0 1.07E+09 8.78E+08 - - - 6.9612 0.9963 221125_WJC_METTL3_EV_vs_WT_F02.17750.17750.2 0.0331 16-Nov K.VDEIFGQLR.D sp|Q9NY12|GAR1_HUMAN 1 1075.5662 1.22 17209 17750 2 1075.560716 538.7904 H\ACA ribonucleoprotein complex subunit 1 OS=Homo sapiens OX=9606 GN=GAR1 PE=1 SV=1 4.37 3230.8 - 5.82E+06 - - - -5.1071 - 2.17 0.402 - 654.2 1 2 0 -0.0055 9 0 0 0 7.12E+08 5.83E+08 - - - 4.2498 0.9973 221125_WJC_METTL3_EV_vs_WT_F02.17762.17762.2 0.0151 14-Aug K.VFQFLNAK[136.11].C "sp|P83731|RL24_HUMAN,tr|C9JNW5|C9JNW5_HUMAN,tr|C9JXB8|C9JXB8_HUMAN" 3 973.5477 0.98 17212 17762 2 973.544645 487.7811 60S ribosomal protein L24 OS=Homo sapiens OX=9606 GN=RPL24 PE=1 SV=1 8.72 3232.5 - 1.15E+07 - - - -3.0887 - 1.573 0.338 - 173.7 1 2 0 -0.003 8 0 0 0 2.71E+08 2.77E+08 - - - 2.9027 1 221125_WJC_METTL3_EV_vs_WT_F02.17771.17771.2 1.11E-06 21/28 R.LLIHQSLAGGIIGVK[136.11].G "sp|P61978|HNRPK_HUMAN,tr|Q5T6W2|Q5T6W2_HUMAN" 2 1525.9435 1.21 17213 17771 2 1525.937595 763.9791 Heterogeneous nuclear ribonucleoprotein K OS=Homo sapiens OX=9606 GN=HNRNPK PE=1 SV=1 8.76 3234 - 8.32E+06 - - - -3.9018 - 3.892 0.639 - 1569.6 1 2 0 -0.006 15 0 0 0 4.74E+08 3.93E+08 - - - 7.0998 0.9997 221125_WJC_METTL3_EV_vs_WT_F02.17774.17774.2 1.81E-05 22-Oct R.GDGVVLVAPPLR[166.11].V sp|P62310|LSM3_HUMAN 1 1201.7058 3.59 17214 17774 2 1201.703684 601.8602 U6 snRNA-associated Sm-like protein LSm3 OS=Homo sapiens OX=9606 GN=LSM3 PE=1 SV=2 5.84 3234.4 - 7.10E+06 - - - -1.7841 - 2.171 0.464 - 484.8 1 2 0 -0.0021 12 0 0 0 9.51E+08 2.65E+08 - - - 4.5071 1 221125_WJC_METTL3_EV_vs_WT_F02.17776.17776.2 2.78E-05 25/28 R.LLIHQSLAGGIIGVK.G "sp|P61978|HNRPK_HUMAN,tr|Q5T6W2|Q5T6W2_HUMAN" 2 1517.9293 1.21 17215 17776 2 1517.925056 759.972 Heterogeneous nuclear ribonucleoprotein K OS=Homo sapiens OX=9606 GN=HNRNPK PE=1 SV=1 8.76 3234.6 - 1.21E+07 - - - -2.8282 - 4.271 0.645 - 2630.1 1 2 0 -0.0043 15 0 0 0 4.74E+08 3.93E+08 - - - 7.3731 0.9618 221125_WJC_METTL3_EV_vs_WT_F02.17780.17780.2 0.068 18-Oct A.NILLQIDNAR.L "sp|Q04695|K1C17_HUMAN,sp|P13645|K1C10_HUMAN,tr|K7EPJ9|K7EPJ9_HUMAN,tr|A0A1B0GVI3|A0A1B0GVI3_HUMAN,tr|F5GWP8|F5GWP8_HUMAN" 5 1168.6564 1813.43 17216 17780 2 1168.654151 585.3355 "Keratin, type I cytoskeletal 17 OS=Homo sapiens OX=9606 GN=KRT17 PE=1 SV=2" 5.84 3235.1 - 1.38E+07 - - - -1.9424 - 2.042 0.335 - 405.8 1 1 0 -0.0023 10 0 0 0 5.53E+08 3.05E+05 - - - 3.5074 0.7961 221125_WJC_METTL3_EV_vs_WT_F02.17795.17795.2 1.49 20-Aug K.EIFSGLPELK[136.11]G.M sp|Q8TEA1|NSUN6_HUMAN 1 1196.6532 0.01 17218 17795 2 1196.651279 599.3339 tRNA (cytosine(72)-C(5))-methyltransferase NSUN6 OS=Homo sapiens OX=9606 GN=NSUN6 PE=1 SV=1 4.53 3237.5 - 3.00E+06 - - - -1.6387 - 1.467 0.208 - 163.4 1 1 0 -0.002 11 0 0 0 2.98E+06 5.06E+08 - - - 1.6134 0.9998 221125_WJC_METTL3_EV_vs_WT_F02.17817.17817.2 0.000667 20-Sep K.LSDFGLC[160.03]TGLK[136.11].K "sp|Q9Y2H1|ST38L_HUMAN,sp|Q15208|STK38_HUMAN,tr|F5H277|F5H277_HUMAN,tr|H0YGN4|H0YGN4_HUMAN" 4 1217.6206 2.36 17220 17817 2 1217.621506 609.8176 Serine\threonine-protein kinase 38-like OS=Homo sapiens OX=9606 GN=STK38L PE=1 SV=3 5.83 3240.9 - 7.40E+06 - - - 0.7769 - 1.726 0.483 - 204.8 1 2 0 0.0009 11 0 0 0 1.62E+09 6.84E+08 - - - 4.0847 0.9996 221125_WJC_METTL3_EV_vs_WT_F02.17825.17825.2 0.000118 20-Nov K.LSDFGLC[160.03]TGLK.K "sp|Q9Y2H1|ST38L_HUMAN,sp|Q15208|STK38_HUMAN,tr|F5H277|F5H277_HUMAN,tr|H0YGN4|H0YGN4_HUMAN" 4 1209.6064 2.39 17222 17825 2 1209.603765 605.8105 Serine\threonine-protein kinase 38-like OS=Homo sapiens OX=9606 GN=STK38L PE=1 SV=3 5.83 3242.1 - 2.82E+07 - - - -2.1453 - 1.92 0.479 - 286.6 1 2 0 -0.0026 11 0 0 0 1.61E+09 6.74E+08 - - - 4.3428 0.9997 221125_WJC_METTL3_EV_vs_WT_F02.17827.17827.2 0.000225 20-Dec K.NSLESYAFNMK[136.11].A "sp|P11142|HSP7C_HUMAN,tr|E9PNE6|E9PNE6_HUMAN,tr|A8K7Q2|A8K7Q2_HUMAN,tr|E9PKE3|E9PKE3_HUMAN,tr|E9PM13|E9PM13_HUMAN,tr|E9PS65|E9PS65_HUMAN" 6 1310.6056 0.11 17224 17827 2 1310.602662 656.3101 Heat shock cognate 71 kDa protein OS=Homo sapiens OX=9606 GN=HSPA8 PE=1 SV=1 6 3242.2 - 3.83E+06 - - - -2.2707 - 2.712 0.471 - 820.3 1 2 0 -0.003 11 0 0 0 5.24E+07 4.95E+08 - - - 5.2178 0.9945 221125_WJC_METTL3_EV_vs_WT_F02.17840.17840.2 0.00157 16-Oct R.VGIFQSFQK[136.11].S sp|Q9NUL7|DDX28_HUMAN 1 1060.5797 1.15 17229 17840 2 1060.575253 531.2971 Probable ATP-dependent RNA helicase DDX28 OS=Homo sapiens OX=9606 GN=DDX28 PE=1 SV=2 8.72 3243.9 - 2.58E+06 - - - -4.1751 - 1.867 0.289 - 249.7 1 2 0 -0.0044 9 0 0 0 9.10E+07 7.89E+07 - - - 2.9804 0.9999 221125_WJC_METTL3_EV_vs_WT_F02.17847.17847.3 0.00018 19/44 R.FATSEELLSHLR[166.11].T "sp|Q9H7S9|ZN703_HUMAN,sp|Q96F45|ZN503_HUMAN" 2 1411.7335 1.45 17233 17847 3 1411.731508 471.5851 Zinc finger protein 703 OS=Homo sapiens OX=9606 GN=ZNF703 PE=1 SV=1 5.4 3244.6 - 6.51E+06 - - - -1.4103 - 2.601 0.431 - 346.8 1 2 0 -0.002 12 0 0 0 1.21E+09 8.34E+08 - - - 5.9943 0.9971 221125_WJC_METTL3_EV_vs_WT_F02.17848.17848.2 0.00323 16-Sep K.LFDWANTSR[166.11].R "sp|Q5T2N8|ATD3C_HUMAN,sp|Q5T9A4|ATD3B_HUMAN,sp|Q9NVI7|ATD3A_HUMAN,tr|Q5SV16|Q5SV16_HUMAN,tr|A0A5K1VW56|A0A5K1VW56_HUMAN" 5 1118.5384 1.05 17234 17848 2 1118.535201 560.2765 ATPase family AAA domain-containing protein 3C OS=Homo sapiens OX=9606 GN=ATAD3C PE=2 SV=2 5.84 3244.7 - 3.81E+06 - - - -2.885 - 1.675 0.29 - 291.4 1 2 0 -0.0032 9 0 0 0 8.74E+07 8.32E+07 - - - 2.6742 0.9671 221125_WJC_METTL3_EV_vs_WT_F02.17849.17849.2 0.000468 16-Jul R.C[160.03]PEALFQPS.F "sp|P63261|ACTG_HUMAN,sp|Q562R1|ACTBL_HUMAN,sp|P60709|ACTB_HUMAN,tr|A0A804GS07|A0A804GS07_HUMAN,tr|E7EVS6|E7EVS6_HUMAN,tr|A0A6Q8PFE4|A0A6Q8PFE4_HUMAN,tr|A0A2R8YEA7|A0A2R8YEA7_HUMAN,tr|A0A2R8Y793|A0A2R8Y793_HUMAN,tr|I3L4N8|I3L4N8_HUMAN" 9 1047.4695 - 17235 17849 2 1047.467715 524.742 "Actin, cytoplasmic 2 OS=Homo sapiens OX=9606 GN=ACTG1 PE=1 SV=1" 4 3244.8 - 2.71E+06 - - - -1.7347 - 1.4 0.475 - 178 1 1 0 -0.0018 9 0 0 0 - - - - - 3.5222 1 221125_WJC_METTL3_EV_vs_WT_F02.17854.17854.2 1.68E-09 16/28 K.VIGIEC[160.03]SSISDYAVK.L "sp|Q99873|ANM1_HUMAN,tr|E9PQ98|E9PQ98_HUMAN,tr|E9PKG1|E9PKG1_HUMAN,tr|E9PNR9|E9PNR9_HUMAN,tr|H0YDE4|H0YDE4_HUMAN,tr|E9PMW9|E9PMW9_HUMAN,tr|E9PIX6|E9PIX6_HUMAN" 7 1639.8127 2.25 17237 17854 2 1639.811653 820.9136 Protein arginine N-methyltransferase 1 OS=Homo sapiens OX=9606 GN=PRMT1 PE=1 SV=3 4.37 3245.5 - 5.52E+06 - - - -0.6531 - 2.966 0.646 - 691.8 1 2 0 -0.0011 15 0 0 0 4.82E+08 2.15E+08 - - - 6.485 0.9999 221125_WJC_METTL3_EV_vs_WT_F02.17856.17856.3 0.00304 18/44 R.FATSEELLSHLR.T "sp|Q9H7S9|ZN703_HUMAN,sp|Q96F45|ZN503_HUMAN" 2 1401.7252 1.45 17238 17856 3 1401.722793 468.249 Zinc finger protein 703 OS=Homo sapiens OX=9606 GN=ZNF703 PE=1 SV=1 5.4 3245.7 - 8.19E+06 - - - -1.7379 - 2.399 0.428 - 269.7 1 2 0 -0.0024 12 0 0 0 1.21E+09 8.34E+08 - - - 5.7366 0.9999 221125_WJC_METTL3_EV_vs_WT_F02.17858.17858.2 1.18E-06 13/22 K.DAGTIAGLNVMR[166.11].L "sp|P11021|BIP_HUMAN,tr|A0A7P0TB36|A0A7P0TB36_HUMAN,tr|A0A7P0TAI0|A0A7P0TAI0_HUMAN" 3 1226.6317 1.25 17239 17858 2 1226.631353 614.3231 Endoplasmic reticulum chaperone BiP OS=Homo sapiens OX=9606 GN=HSPA5 PE=1 SV=2 5.84 3245.9 - 4.09E+06 - - - -0.2633 - 2.54 0.539 - 616.6 1 2 0 -0.0003 12 0 0 0 5.65E+08 4.54E+08 - - - 5.4746 0.9944 221125_WJC_METTL3_EV_vs_WT_F02.17862.17862.2 0.598 16-Sep K.LNLGGDFIK.E "sp|Q9BSR8|YIPF4_HUMAN,tr|H7C0D5|H7C0D5_HUMAN" 2 975.5389 1.25 17240 17862 2 975.536101 488.7767 Protein YIPF4 OS=Homo sapiens OX=9606 GN=YIPF4 PE=1 SV=1 5.84 3246.4 - 2.90E+06 - - - -2.902 - 1.769 0.193 - 230.4 1 2 0 -0.0028 9 0 0 0 1.24E+08 9.88E+07 - - - 2.1158 0.9994 221125_WJC_METTL3_EV_vs_WT_F02.17864.17864.2 0.00753 16-Dec K.QALAWMVSR[166.11].E "sp|Q14527|HLTF_HUMAN,tr|A0A0C4DGA6|A0A0C4DGA6_HUMAN" 2 1070.5571 0.81 17241 17864 2 1070.554176 536.2858 Helicase-like transcription factor OS=Homo sapiens OX=9606 GN=HLTF PE=1 SV=2 9.75 3246.7 - 2.71E+06 - - - -2.6893 - 2.391 0.358 - 594.2 1 2 0 -0.0029 9 0 0 0 8.23E+07 1.02E+08 - - - 4.2062 0.9997 221125_WJC_METTL3_EV_vs_WT_F02.17866.17866.2 4.34E-08 13/22 R.GPFTDVVTTNLK.L "sp|O95292|VAPB_HUMAN,sp|Q9P0L0|VAPA_HUMAN,tr|E5RK64|E5RK64_HUMAN" 3 1290.682 4.36 17243 17866 2 1290.678659 646.3483 Vesicle-associated membrane protein-associated protein B\C OS=Homo sapiens OX=9606 GN=VAPB PE=1 SV=3 5.84 3246.9 - 4.11E+06 - - - -2.563 - 2.507 0.577 - 567.2 1 2 0 -0.0033 12 0 0 0 2.90E+08 6.65E+07 - - - 5.72 0.9996 221125_WJC_METTL3_EV_vs_WT_F02.17869.17869.2 0.000492 18-Oct R.FEELLLQASK[136.11].E "sp|Q9NWS0|PIHD1_HUMAN,tr|M0QXD5|M0QXD5_HUMAN,tr|M0R3A8|M0R3A8_HUMAN,tr|M0R0J2|M0R0J2_HUMAN" 4 1184.6532 1.16 17244 17869 2 1184.650238 593.3339 PIH1 domain-containing protein 1 OS=Homo sapiens OX=9606 GN=PIH1D1 PE=1 SV=1 4.53 3247.3 - 8.46E+06 - - - -2.5341 - 2.236 0.483 - 289.5 1 2 0 -0.003 10 0 0 0 9.66E+08 8.35E+08 - - - 4.8536 1 221125_WJC_METTL3_EV_vs_WT_F02.17870.17870.2 1.05E-08 17/28 K.VIGIEC[160.03]SSISDYAVK[136.11].L "sp|Q99873|ANM1_HUMAN,tr|E9PQ98|E9PQ98_HUMAN,tr|E9PKG1|E9PKG1_HUMAN,tr|E9PNR9|E9PNR9_HUMAN,tr|H0YDE4|H0YDE4_HUMAN,tr|E9PMW9|E9PMW9_HUMAN,tr|E9PIX6|E9PIX6_HUMAN" 7 1647.8269 2.25 17245 17870 2 1647.826494 824.9207 Protein arginine N-methyltransferase 1 OS=Homo sapiens OX=9606 GN=PRMT1 PE=1 SV=3 4.37 3247.3 - 5.08E+06 - - - -0.2609 - 3.014 0.557 - 790.6 1 2 0 -0.0004 15 0 0 0 4.82E+08 2.15E+08 - - - 5.8673 1 221125_WJC_METTL3_EV_vs_WT_F02.17875.17875.2 1.47E-09 16/22 R.FATSEELLSHLR[166.11].T "sp|Q9H7S9|ZN703_HUMAN,sp|Q96F45|ZN503_HUMAN" 2 1411.7335 1.44 17247 17875 2 1411.73203 706.874 Zinc finger protein 703 OS=Homo sapiens OX=9606 GN=ZNF703 PE=1 SV=1 5.4 3248 - 5.26E+06 - - - -1.0406 - 3.031 0.622 - 1027.3 1 2 0 -0.0015 12 0 0 0 2.08E+08 1.45E+08 - - - 6.5523 1 221125_WJC_METTL3_EV_vs_WT_F02.17876.17876.2 6.86E-07 15/22 R.FATSEELLSHLR.T "sp|Q9H7S9|ZN703_HUMAN,sp|Q96F45|ZN503_HUMAN" 2 1401.7252 1.44 17248 17876 2 1401.717611 701.8699 Zinc finger protein 703 OS=Homo sapiens OX=9606 GN=ZNF703 PE=1 SV=1 5.4 3248.1 - 6.53E+06 - - - -5.4347 - 2.9 0.611 - 916.9 1 2 0 -0.0076 12 0 0 0 2.08E+08 1.45E+08 - - - 6.3529 0.7798 221125_WJC_METTL3_EV_vs_WT_F02.17881.17881.2 0.0225 14-Jul R.LHVSNIPF.R "sp|O43251|RFOX2_HUMAN,sp|Q9NWB1|RFOX1_HUMAN,sp|A6NFN3|RFOX3_HUMAN,tr|A0A6Q8PGE0|A0A6Q8PGE0_HUMAN,tr|A0A6Q8PH77|A0A6Q8PH77_HUMAN,tr|A0A286YEU2|A0A286YEU2_HUMAN,tr|A0A087X2B1|A0A087X2B1_HUMAN,tr|F8VR27|F8VR27_HUMAN,tr|B7Z1U7|B7Z1U7_HUMAN,tr|B0QYY6|B0QYY6_HUMAN,tr|B0QYV1|B0QYV1_HUMAN,tr|A0A6Q8PHA3|A0A6Q8PHA3_HUMAN,tr|A0A3B3ITL7|A0A3B3ITL7_HUMAN,tr|F8VZY7|F8VZY7_HUMAN,tr|B0QYY4|B0QYY4_HUMAN,tr|J3KNW3|J3KNW3_HUMAN,tr|F8VZG9|F8VZG9_HUMAN,tr|J3QRF4|J3QRF4_HUMAN,tr|F8VRS4|F8VRS4_HUMAN,tr|A0A6Q8PFM4|A0A6Q8PFM4_HUMAN,tr|S4R469|S4R469_HUMAN,tr|A0A804HKG7|A0A804HKG7_HUMAN,tr|A0A0G2JRA5|A0A0G2JRA5_HUMAN,tr|A0A804HJM2|A0A804HJM2_HUMAN,tr|J3QQZ2|J3QQZ2_HUMAN,tr|I3L1D4|I3L1D4_HUMAN,tr|B0QYY7|B0QYY7_HUMAN,tr|A0A0G2JSB3|A0A0G2JSB3_HUMAN" 28 925.5022 - 17251 17881 2 925.500301 463.7584 RNA binding protein fox-1 homolog 2 OS=Homo sapiens OX=9606 GN=RBFOX2 PE=1 SV=3 6.74 3248.7 - 2.06E+06 - - - -2 - 1.384 0.231 - 148.1 1 1 0 -0.0019 8 0 0 0 - - - - - 1.7267 0.9994 221125_WJC_METTL3_EV_vs_WT_F02.17893.17893.2 0.00376 14/20 R.QITLNDLPVGR[166.11].S "sp|Q13162|PRDX4_HUMAN,tr|H7C3T4|H7C3T4_HUMAN" 2 1234.6909 6.03 17257 17893 2 1234.687683 618.3527 Peroxiredoxin-4 OS=Homo sapiens OX=9606 GN=PRDX4 PE=1 SV=1 5.84 3250.2 - 1.19E+06 - - - -2.6104 - 2.256 0.4 - 1040.4 1 2 0 -0.0032 11 0 0 0 4.33E+08 7.18E+07 - - - 4.1954 0.9979 221125_WJC_METTL3_EV_vs_WT_F02.17894.17894.2 0.0909 20-Aug K.TVALDGTLFQK.S "sp|Q14683|SMC1A_HUMAN,tr|G8JLG1|G8JLG1_HUMAN,tr|A0A6Q8PHC3|A0A6Q8PHC3_HUMAN" 3 1191.6499 0.79 17258 17894 2 1191.647727 596.8322 Structural maintenance of chromosomes protein 1A OS=Homo sapiens OX=9606 GN=SMC1A PE=1 SV=2 5.5 3250.2 - 1.66E+06 - - - -1.8562 - 1.631 0.264 - 143.3 1 2 0 -0.0022 11 0 0 0 1.32E+08 1.66E+08 - - - 2.3136 1 221125_WJC_METTL3_EV_vs_WT_F02.17898.17898.2 5.74E-08 13/22 R.VFASELNAGIIK.T "sp|Q9P2J5|SYLC_HUMAN,tr|A0A6I8PIV1|A0A6I8PIV1_HUMAN,tr|A0A6I8PRS0|A0A6I8PRS0_HUMAN,tr|A0A6I8PLB8|A0A6I8PLB8_HUMAN,tr|A0A6I8PIT3|A0A6I8PIT3_HUMAN,tr|A0A6I8PLB3|A0A6I8PLB3_HUMAN,tr|A0A6I8PS05|A0A6I8PS05_HUMAN,tr|B4DER1|B4DER1_HUMAN,tr|A0A6I8PL42|A0A6I8PL42_HUMAN" 9 1260.7078 0.94 17260 17898 2 1260.705488 631.3612 "Leucine--tRNA ligase, cytoplasmic OS=Homo sapiens OX=9606 GN=LARS1 PE=1 SV=2" 5.97 3250.7 - 3.85E+06 - - - -1.8244 - 2.542 0.606 - 420.7 1 2 0 -0.0023 12 0 0 0 5.48E+07 5.83E+07 - - - 5.9709 0.9997 221125_WJC_METTL3_EV_vs_WT_F02.17900.17900.2 1.55E-07 14/22 R.VFASELNAGIIK[136.11].T "sp|Q9P2J5|SYLC_HUMAN,tr|A0A6I8PIV1|A0A6I8PIV1_HUMAN,tr|A0A6I8PRS0|A0A6I8PRS0_HUMAN,tr|A0A6I8PLB8|A0A6I8PLB8_HUMAN,tr|A0A6I8PIT3|A0A6I8PIT3_HUMAN,tr|A0A6I8PLB3|A0A6I8PLB3_HUMAN,tr|A0A6I8PS05|A0A6I8PS05_HUMAN,tr|B4DER1|B4DER1_HUMAN,tr|A0A6I8PL42|A0A6I8PL42_HUMAN" 9 1268.722 0.94 17261 17900 2 1268.718341 635.3683 "Leucine--tRNA ligase, cytoplasmic OS=Homo sapiens OX=9606 GN=LARS1 PE=1 SV=2" 5.97 3250.9 - 2.82E+06 - - - -2.8745 - 2.567 0.55 - 502.6 1 2 0 -0.0036 12 0 0 0 5.48E+07 5.83E+07 - - - 5.5827 0.9722 221125_WJC_METTL3_EV_vs_WT_F02.17902.17902.2 0.00185 13/24 K.PFGSEEQLLPVEK.L "sp|O75643|U520_HUMAN,tr|A0A494C1A5|A0A494C1A5_HUMAN" 2 1471.7559 3.05 17262 17902 2 1471.755437 736.8852 U5 small nuclear ribonucleoprotein 200 kDa helicase OS=Homo sapiens OX=9606 GN=SNRNP200 PE=1 SV=2 4.25 3251.1 - 4.61E+06 - - - -0.2881 - 1.812 0.339 - 160.4 1 1 0 -0.0004 13 0 0 0 7.85E+07 2.57E+07 - - - 3.0703 0.999 221125_WJC_METTL3_EV_vs_WT_F02.17903.17903.2 0.0153 12-Jul K.INWASFR.R sp|Q9H0W5|CCDC8_HUMAN 1 892.4555 1 17263 17903 2 892.454285 447.235 Coiled-coil domain-containing protein 8 OS=Homo sapiens OX=9606 GN=CCDC8 PE=1 SV=2 9.75 3251.2 - 888132 - - - -1.4018 - 1.609 0.29 - 163.8 1 2 0 -0.0013 7 0 0 0 4.26E+07 4.24E+07 - - - 2.6896 1 221125_WJC_METTL3_EV_vs_WT_F02.17904.17904.2 1.23E-06 18/30 R.VYTADPYHALAPAASY.G "sp|O43251|RFOX2_HUMAN,tr|B0QYV1|B0QYV1_HUMAN,tr|A0A0G2JRD1|A0A0G2JRD1_HUMAN,tr|A0A0G2JRA5|A0A0G2JRA5_HUMAN,tr|S4R3K7|S4R3K7_HUMAN" 5 1708.8097 - 17264 17904 2 1708.805714 855.4121 RNA binding protein fox-1 homolog 2 OS=Homo sapiens OX=9606 GN=RBFOX2 PE=1 SV=3 5.08 3251.3 - 2.75E+06 - - - -2.325 - 3.226 0.633 - 872.7 1 1 0 -0.004 16 0 0 0 - - - - - 6.5946 0.9996 221125_WJC_METTL3_EV_vs_WT_F02.17909.17909.2 2.22E-06 13/22 R.YIGEVGDIVVGR[166.11].L "sp|Q13868|EXOS2_HUMAN,tr|A3KFL1|A3KFL1_HUMAN,tr|A3KFL2|A3KFL2_HUMAN,tr|A3KFL5|A3KFL5_HUMAN" 4 1285.6906 0.18 17267 17909 2 1285.687413 643.8526 Exosome complex component RRP4 OS=Homo sapiens OX=9606 GN=EXOSC2 PE=1 SV=2 4.37 3252 - 3.02E+06 - - - -2.457 - 2.065 0.501 - 482.2 1 2 0 -0.0032 12 0 0 0 1.15E+07 6.50E+07 - - - 4.6483 0.9998 221125_WJC_METTL3_EV_vs_WT_F02.17910.17910.2 1.81E-05 18-Dec K.LWTLVSEQTR[166.11].V "sp|P46776|RL27A_HUMAN,tr|E9PLL6|E9PLL6_HUMAN,tr|E9PJD9|E9PJD9_HUMAN" 3 1241.6644 0.92 17268 17910 2 1241.66323 621.8395 60S ribosomal protein L27a OS=Homo sapiens OX=9606 GN=RPL27A PE=1 SV=2 6 3252.1 - 2.22E+06 - - - -0.9077 - 2.292 0.415 - 656.4 1 2 0 -0.0011 10 0 0 0 2.14E+08 2.34E+08 - - - 4.421 0.9857 221125_WJC_METTL3_EV_vs_WT_F02.17911.17911.2 0.000112 13/28 K.SINPDEAVAYGAAVQ.A "sp|P54652|HSP72_HUMAN,sp|P0DMV8|HS71A_HUMAN,sp|P34931|HS71L_HUMAN,sp|P11142|HSP7C_HUMAN,sp|P0DMV9|HS71B_HUMAN,sp|P17066|HSP76_HUMAN,tr|E9PNE6|E9PNE6_HUMAN,tr|A8K7Q2|A8K7Q2_HUMAN,tr|E9PKE3|E9PKE3_HUMAN,tr|Q53FA3|Q53FA3_HUMAN,tr|V9GZ37|V9GZ37_HUMAN,tr|A0A0G2JIW1|A0A0G2JIW1_HUMAN" 12 1503.7205 - 17269 17911 2 1503.719278 752.8675 Heat shock-related 70 kDa protein 2 OS=Homo sapiens OX=9606 GN=HSPA2 PE=1 SV=1 3.67 3252.2 - 2.21E+06 - - - -0.8379 - 1.932 0.451 - 267.8 1 1 0 -0.0013 15 0 0 0 - - - - - 3.9908 0.9999 221125_WJC_METTL3_EV_vs_WT_F02.17912.17912.3 2.46E-05 15/44 K.LLSAAYITSHLK.T "sp|Q14119|VEZF1_HUMAN,tr|J3QSH4|J3QSH4_HUMAN,tr|J9JIC7|J9JIC7_HUMAN" 3 1315.75 1.03 17270 17912 3 1315.747188 439.5906 Vascular endothelial zinc finger 1 OS=Homo sapiens OX=9606 GN=VEZF1 PE=1 SV=2 8.6 3252.3 - 2.19E+06 - - - -2.1273 - 2.628 0.478 - 320.8 1 2 0 -0.0028 12 0 0 0 2.15E+07 2.08E+07 - - - 6.5467 0.9883 221125_WJC_METTL3_EV_vs_WT_F02.17914.17914.2 1.08E-07 26-Dec L.GIYPAVDPLDSTSR.L "sp|P06576|ATPB_HUMAN,tr|H0YH81|H0YH81_HUMAN" 2 1489.7413 999 17272 17914 2 1489.743918 745.8779 "ATP synthase subunit beta, mitochondrial OS=Homo sapiens OX=9606 GN=ATP5F1B PE=1 SV=3" 4.21 3252.6 - 1.27E+06 - - - 1.7755 - 2.075 0.595 - 342.1 1 1 0 0.0026 14 0 0 0 2.10E+07 0.00E+00 - - - 5.2666 0.9902 221125_WJC_METTL3_EV_vs_WT_F02.17915.17915.2 0.000161 13/20 K.QVMMFSATLSK[136.11].E "sp|Q13838|DX39B_HUMAN,tr|A0A140TA18|A0A140TA18_HUMAN,tr|F6UJC5|F6UJC5_HUMAN,tr|F6TRA5|F6TRA5_HUMAN,tr|F6WLT2|F6WLT2_HUMAN,tr|Q5STU3|Q5STU3_HUMAN,tr|A0A140T973|A0A140T973_HUMAN,tr|A0A140T9X9|A0A140T9X9_HUMAN,tr|A0A140T996|A0A140T996_HUMAN,tr|A0A0G2JJZ9|A0A0G2JJZ9_HUMAN,tr|A0A140T9K1|A0A140T9K1_HUMAN,tr|A0A140T9X3|A0A140T9X3_HUMAN,tr|H0YCC6|H0YCC6_HUMAN,tr|A0A0A0MT12|A0A0A0MT12_HUMAN" 14 1249.629 1.17 17273 17915 2 1249.619997 625.8218 Spliceosome RNA helicase DDX39B OS=Homo sapiens OX=9606 GN=DDX39B PE=1 SV=1 8.75 3252.7 - 1.67E+06 - - - -7.2173 - 2.373 0.487 - 679.4 1 2 0 -0.009 11 0 0 0 3.82E+07 3.26E+07 - - - 4.9729 0.9987 221125_WJC_METTL3_EV_vs_WT_F02.17916.17916.2 0.0138 20-Jul K.LLTQGFTNWNK[136.11].R sp|O60264|SMCA5_HUMAN 1 1328.6968 3.15 17274 17916 2 1328.696249 665.3557 SWI\SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A member 5 OS=Homo sapiens OX=9606 GN=SMARCA5 PE=1 SV=1 8.75 3252.9 - 0 - - - -0.4418 - 1.476 0.283 - 152 1 2 0 -0.0006 11 0 0 0 4.38E+07 1.39E+07 - - - 2.1843 0.9956 221125_WJC_METTL3_EV_vs_WT_F02.17920.17920.2 0.255 20-Sep K.TVALDGTLFQK[136.11].S "sp|Q14683|SMC1A_HUMAN,tr|G8JLG1|G8JLG1_HUMAN,tr|A0A6Q8PHC3|A0A6Q8PHC3_HUMAN" 3 1199.6641 0.79 17276 17920 2 1199.660342 600.8393 Structural maintenance of chromosomes protein 1A OS=Homo sapiens OX=9606 GN=SMC1A PE=1 SV=2 5.5 3253.3 - 7.14E+06 - - - -3.1651 - 1.746 0.264 - 171.6 1 2 0 -0.0038 11 0 0 0 1.32E+08 1.66E+08 - - - 2.4974 0.9988 221125_WJC_METTL3_EV_vs_WT_F02.17922.17922.2 0.00423 18-Oct K.LWTLVSEQTR.V "sp|P46776|RL27A_HUMAN,tr|E9PLL6|E9PLL6_HUMAN,tr|E9PJD9|E9PJD9_HUMAN" 3 1231.6561 0.92 17278 17922 2 1231.652251 616.8353 60S ribosomal protein L27a OS=Homo sapiens OX=9606 GN=RPL27A PE=1 SV=2 6 3253.4 - 4.39E+06 - - - -3.1145 - 2.131 0.354 - 483 1 2 0 -0.0038 10 0 0 0 2.14E+08 2.34E+08 - - - 3.7663 1 221125_WJC_METTL3_EV_vs_WT_F02.17923.17923.2 1.26E-05 18/26 R.YGPLSGVNVVYDQR.T sp|Q13595|TRA2A_HUMAN 1 1565.7838 1.46 17279 17923 2 1565.78275 783.8992 Transformer-2 protein homolog alpha OS=Homo sapiens OX=9606 GN=TRA2A PE=1 SV=1 5.83 3253.5 - 4.06E+06 - - - -0.6751 - 3.201 0.63 - 1062.7 1 2 0 -0.0011 14 0 0 0 8.39E+07 5.73E+07 - - - 6.6135 0.8178 221125_WJC_METTL3_EV_vs_WT_F02.17925.17925.2 0.136 14-Oct A.LQVEEILK[136.11].N "sp|O94829|IPO13_HUMAN,sp|Q9H6R4|NOL6_HUMAN,tr|A0A0A0MRW6|A0A0A0MRW6_HUMAN" 3 978.5841 0.9 17281 17925 2 978.581049 490.2993 Importin-13 OS=Homo sapiens OX=9606 GN=IPO13 PE=1 SV=3 4.53 3253.7 - 3.12E+06 - - - -3.1157 - 1.733 0.26 - 255.2 1 1 0 -0.003 8 0 0 0 6.13E+07 6.83E+07 - - - 2.6187 1 221125_WJC_METTL3_EV_vs_WT_F02.17926.17926.2 0.00121 16/26 R.YGPLSGVNVVYDQR[166.11].T sp|Q13595|TRA2A_HUMAN 1 1575.7921 1.47 17282 17926 2 1575.789553 788.9033 Transformer-2 protein homolog alpha OS=Homo sapiens OX=9606 GN=TRA2A PE=1 SV=1 5.83 3253.8 - 2.78E+06 - - - -1.6017 - 3.15 0.601 - 698.6 1 2 0 -0.0025 14 0 0 0 9.19E+07 6.26E+07 - - - 6.3585 0.9996 221125_WJC_METTL3_EV_vs_WT_F02.17927.17927.2 0.00215 20-Nov R.VGVIGFPNVGK.S sp|Q9BVP2|GNL3_HUMAN 1 1085.6233 0.79 17283 17927 2 1085.621265 543.8189 Guanine nucleotide-binding protein-like 3 OS=Homo sapiens OX=9606 GN=GNL3 PE=1 SV=2 8.72 3253.9 - 2.54E+06 - - - -1.9021 - 2.395 0.388 - 418.3 1 2 0 -0.0021 11 0 0 0 4.75E+07 6.01E+07 - - - 4.2688 0.9984 221125_WJC_METTL3_EV_vs_WT_F02.17928.17928.2 1.14E-05 13/24 R.VLLTTQGVDMISK[136.11].M "sp|Q14204|DYHC1_HUMAN,tr|A0A7P0T9C4|A0A7P0T9C4_HUMAN,tr|A0A2R8Y706|A0A2R8Y706_HUMAN,tr|A0A7P0TAW9|A0A7P0TAW9_HUMAN,tr|A0A7P0TA13|A0A7P0TA13_HUMAN,tr|A0A7P0T7V5|A0A7P0T7V5_HUMAN,tr|A0A7P0T9R4|A0A7P0T9R4_HUMAN,tr|A0A2R8Y5T0|A0A2R8Y5T0_HUMAN" 8 1411.7836 0.66 17284 17928 2 1411.790504 706.8991 Cytoplasmic dynein 1 heavy chain 1 OS=Homo sapiens OX=9606 GN=DYNC1H1 PE=1 SV=5 5.81 3254 - 2.50E+06 - - - 4.8889 - 2.595 0.552 - 488.6 1 2 0 0.0069 13 0 0 0 2.52E+07 3.80E+07 - - - 5.5633 0.8499 221125_WJC_METTL3_EV_vs_WT_F02.17929.17929.2 0.303 14-Sep A.LQVEEILK.N "sp|O94829|IPO13_HUMAN,sp|Q9H6R4|NOL6_HUMAN,tr|A0A0A0MRW6|A0A0A0MRW6_HUMAN" 3 970.5699 0.9 17285 17929 2 970.567436 486.2922 Importin-13 OS=Homo sapiens OX=9606 GN=IPO13 PE=1 SV=3 4.53 3254.2 - 2.46E+06 - - - -2.5367 - 1.746 0.233 - 197.1 1 1 0 -0.0025 8 0 0 0 6.03E+07 6.70E+07 - - - 2.442 0.9987 221125_WJC_METTL3_EV_vs_WT_F02.17930.17930.3 0.0139 Oct-44 K.LLSAAYITSHLK[136.11].T "sp|Q14119|VEZF1_HUMAN,tr|J3QSH4|J3QSH4_HUMAN,tr|J9JIC7|J9JIC7_HUMAN" 3 1323.7642 1.03 17286 17930 3 1323.762062 442.262 Vascular endothelial zinc finger 1 OS=Homo sapiens OX=9606 GN=VEZF1 PE=1 SV=2 8.6 3254.3 - 1.88E+06 - - - -1.6053 - 1.783 0.287 - 119.9 1 2 0 -0.0021 12 0 0 0 2.15E+07 2.08E+07 - - - 3.3421 0.9999 221125_WJC_METTL3_EV_vs_WT_F02.17931.17931.2 3.05E-06 20-Dec K.MDEVLYSIAEK.V "sp|P83876|TXN4A_HUMAN,tr|K7EPA6|K7EPA6_HUMAN,tr|O14835|O14835_HUMAN,tr|K7ES07|K7ES07_HUMAN,tr|K7EJU2|K7EJU2_HUMAN,tr|K7EMX5|K7EMX5_HUMAN" 6 1296.6272 5.11 17287 17931 2 1296.625142 649.3209 Thioredoxin-like protein 4A OS=Homo sapiens OX=9606 GN=TXNL4A PE=1 SV=1 4.14 3254.4 - 1.79E+06 - - - -1.5525 - 2.465 0.537 - 734.2 1 2 0 -0.002 11 0 0 0 2.95E+07 5.79E+06 - - - 5.4473 0.9998 221125_WJC_METTL3_EV_vs_WT_F02.17934.17934.2 0.000197 18-Oct K.AEVVLGNIIK.K "sp|Q13303|KCAB2_HUMAN,tr|K7EKU4|K7EKU4_HUMAN,tr|A0A590UJV4|A0A590UJV4_HUMAN,tr|A0A590UJJ4|A0A590UJJ4_HUMAN,tr|Q5TG78|Q5TG78_HUMAN,tr|A0A590UJY1|A0A590UJY1_HUMAN,tr|K7EIR5|K7EIR5_HUMAN,tr|A0A590UJB8|A0A590UJB8_HUMAN,tr|Q5TG84|Q5TG84_HUMAN,tr|A0A590UK89|A0A590UK89_HUMAN,tr|Q5TG81|Q5TG81_HUMAN,tr|A0A5F9UN28|A0A5F9UN28_HUMAN,tr|A0A590UJU1|A0A590UJU1_HUMAN,tr|A0A590UJB6|A0A590UJB6_HUMAN,tr|A0A590UJU4|A0A590UJU4_HUMAN" 15 1054.6386 1.83 17288 17934 2 1054.637791 528.3266 Voltage-gated potassium channel subunit beta-2 OS=Homo sapiens OX=9606 GN=KCNAB2 PE=1 SV=2 6.05 3254.8 - 8.15E+06 - - - -0.8107 - 1.951 0.481 - 373.4 1 2 0 -0.0009 10 0 0 0 9.74E+07 5.31E+07 - - - 4.4589 0.9998 221125_WJC_METTL3_EV_vs_WT_F02.17935.17935.2 0.000628 20-Dec R.VGVIGFPNVGK[136.11].S sp|Q9BVP2|GNL3_HUMAN 1 1093.6375 0.9 17289 17935 2 1093.636577 547.826 Guanine nucleotide-binding protein-like 3 OS=Homo sapiens OX=9606 GN=GNL3 PE=1 SV=2 8.72 3254.9 - 3.74E+06 - - - -0.8714 - 2.304 0.407 - 468.9 1 2 0 -0.001 11 0 0 0 8.10E+07 8.97E+07 - - - 4.3047 0.9999 221125_WJC_METTL3_EV_vs_WT_F02.17938.17938.2 9.64E-07 14/24 R.VLLTTQGVDMISK.M "sp|Q14204|DYHC1_HUMAN,tr|A0A7P0T9C4|A0A7P0T9C4_HUMAN,tr|A0A2R8Y706|A0A2R8Y706_HUMAN,tr|A0A7P0TAW9|A0A7P0TAW9_HUMAN,tr|A0A7P0TA13|A0A7P0TA13_HUMAN,tr|A0A7P0T7V5|A0A7P0T7V5_HUMAN,tr|A0A7P0T9R4|A0A7P0T9R4_HUMAN,tr|A0A2R8Y5T0|A0A2R8Y5T0_HUMAN" 8 1403.7694 0.66 17292 17938 2 1403.770161 702.892 Cytoplasmic dynein 1 heavy chain 1 OS=Homo sapiens OX=9606 GN=DYNC1H1 PE=1 SV=5 5.81 3255.1 - 2.67E+06 - - - 0.5407 - 2.754 0.524 - 645.3 1 2 0 0.0008 13 0 0 0 2.52E+07 3.80E+07 - - - 5.5111 1 221125_WJC_METTL3_EV_vs_WT_F02.17940.17940.2 8.86E-05 22-Dec R.YWLC[160.03]AATGPSIK[136.11].L "sp|P63244|RACK1_HUMAN,tr|H0YAM7|H0YAM7_HUMAN,tr|H0YAF8|H0YAF8_HUMAN,tr|H0Y9P0|H0Y9P0_HUMAN,tr|D6RF23|D6RF23_HUMAN,tr|J3KPE3|J3KPE3_HUMAN,tr|D6RAC2|D6RAC2_HUMAN,tr|H0Y8R5|H0Y8R5_HUMAN,tr|D6REE5|D6REE5_HUMAN,tr|H0Y8W2|H0Y8W2_HUMAN" 10 1373.6893 1.31 17294 17940 2 1373.686835 687.8519 Receptor of activated protein C kinase 1 OS=Homo sapiens OX=9606 GN=RACK1 PE=1 SV=3 8.2 3255.3 - 2.13E+06 - - - -1.8003 - 2.345 0.604 - 481.4 1 2 0 -0.0025 12 0 0 0 6.82E+07 5.19E+07 - - - 5.7439 0.9995 221125_WJC_METTL3_EV_vs_WT_F02.17941.17941.2 1.63E-05 16-Oct K.SNELFTTFR.Q sp|Q9NUQ3|TXLNG_HUMAN 1 1113.5455 1.16 17295 17941 2 1113.542841 557.78 Gamma-taxilin OS=Homo sapiens OX=9606 GN=TXLNG PE=1 SV=2 5.72 3255.4 - 2.03E+06 - - - -2.3645 - 2.049 0.432 - 415.9 1 2 0 -0.0026 9 0 0 0 3.16E+07 2.72E+07 - - - 4.3063 0.9766 221125_WJC_METTL3_EV_vs_WT_F02.17944.17944.2 0.0859 14-Jul R.YIEIFPSR[166.11].R "sp|Q12849|GRSF1_HUMAN,tr|H0YAK1|H0YAK1_HUMAN,tr|H0Y8R1|H0Y8R1_HUMAN,tr|F5H5I6|F5H5I6_HUMAN" 4 1033.5472 1.17 17298 17944 2 1033.550016 517.7809 G-rich sequence factor 1 OS=Homo sapiens OX=9606 GN=GRSF1 PE=1 SV=3 6 3255.8 - 1.45E+06 - - - 2.7227 - 1.333 0.158 - 142.8 2 2 0 0.0028 8 0 0 0 2.45E+07 2.10E+07 - - - 0.9395 0.9998 221125_WJC_METTL3_EV_vs_WT_F02.17946.17946.2 0.000466 18-Sep K.FAAQELIEVK[136.11].R "sp|Q86U44|MTA70_HUMAN,tr|F5H6D8|F5H6D8_HUMAN,tr|H0YFV6|H0YFV6_HUMAN,tr|B4DTN4|B4DTN4_HUMAN" 4 1154.6427 0.03 17299 17946 2 1154.64286 578.3286 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 4.53 3256 - 9.35E+08 - - - 0.1602 - 1.89 0.436 - 203.3 1 2 0 0.0002 10 0 0 0 2.86E+10 8.50E+11 - - - 4.0381 1 221125_WJC_METTL3_EV_vs_WT_F02.17949.17949.2 1.64E-06 13/22 R.YWLC[160.03]AATGPSIK.L "sp|P63244|RACK1_HUMAN,tr|H0YAM7|H0YAM7_HUMAN,tr|H0YAF8|H0YAF8_HUMAN,tr|H0Y9P0|H0Y9P0_HUMAN,tr|D6RF23|D6RF23_HUMAN,tr|J3KPE3|J3KPE3_HUMAN,tr|D6RAC2|D6RAC2_HUMAN,tr|H0Y8R5|H0Y8R5_HUMAN,tr|D6REE5|D6REE5_HUMAN,tr|H0Y8W2|H0Y8W2_HUMAN" 10 1365.6751 1.31 17301 17949 2 1365.672911 683.8448 Receptor of activated protein C kinase 1 OS=Homo sapiens OX=9606 GN=RACK1 PE=1 SV=3 8.2 3256.3 - 3.44E+06 - - - -1.6087 - 2.441 0.648 - 612.2 1 2 0 -0.0022 12 0 0 0 6.82E+07 5.19E+07 - - - 6.1745 0.9971 221125_WJC_METTL3_EV_vs_WT_F02.17951.17951.2 0.00236 16-Aug R.ALPEFFNGK[136.11].N "sp|Q8TAQ2|SMRC2_HUMAN,sp|Q92922|SMRC1_HUMAN,tr|F8VXC8|F8VXC8_HUMAN" 3 1029.5375 3.25 17303 17951 2 1029.534485 515.776 SWI\SNF complex subunit SMARCC2 OS=Homo sapiens OX=9606 GN=SMARCC2 PE=1 SV=1 6.05 3256.5 - 1.85E+06 - - - -2.911 - 1.589 0.316 - 202.4 1 2 0 -0.003 9 0 0 0 1.99E+08 6.13E+07 - - - 2.7138 0.9997 221125_WJC_METTL3_EV_vs_WT_F02.17952.17952.2 0.3 16-Oct R.FEAPLFNAR[166.11].L "sp|P28331|NDUS1_HUMAN,tr|B4DJ81|B4DJ81_HUMAN" 2 1073.5533 1.47 17304 17952 2 1073.552798 537.784 "NADH-ubiquinone oxidoreductase 75 kDa subunit, mitochondrial OS=Homo sapiens OX=9606 GN=NDUFS1 PE=1 SV=3" 6 3256.6 - 1.44E+06 - - - -0.5142 - 1.809 0.393 - 347.3 1 2 0 -0.0006 9 0 0 0 4.55E+07 3.10E+07 - - - 3.6585 0.8789 221125_WJC_METTL3_EV_vs_WT_F02.17954.17954.2 0.0499 16-Jun E.GLPEGIPFR.R "sp|P78347|GTF2I_HUMAN,sp|P78347|GTF2I_HUMAN,tr|A0A494C0Q7|A0A494C0Q7_HUMAN,tr|A0A494C1K3|A0A494C1K3_HUMAN,tr|A0A494C1K3|A0A494C1K3_HUMAN" 5 984.5393 3.35 17306 17954 2 984.538762 493.2769 General transcription factor II-I OS=Homo sapiens OX=9606 GN=GTF2I PE=1 SV=2 6 3256.9 - 673804 - - - -0.5119 - 1.387 0.251 - 77.1 2 1 0 -0.0005 9 0 0 0 2.25E+07 6.73E+06 - - - 1.7067 0.9947 221125_WJC_METTL3_EV_vs_WT_F02.17958.17958.2 0.00417 16-Oct K.SNELFTTFR[166.11].Q sp|Q9NUQ3|TXLNG_HUMAN 1 1123.5537 1.16 17308 17958 2 1123.549226 562.7841 Gamma-taxilin OS=Homo sapiens OX=9606 GN=TXLNG PE=1 SV=2 5.72 3257.4 - 2.58E+06 - - - -4.0212 - 1.573 0.347 - 224.6 1 2 0 -0.0045 9 0 0 0 3.16E+07 2.72E+07 - - - 2.913 0.9998 221125_WJC_METTL3_EV_vs_WT_F02.17959.17959.2 2.35E-05 14/22 K.TLLENTAITIGR[166.11].L "sp|Q92973|TNPO1_HUMAN,tr|S4R398|S4R398_HUMAN,tr|A0A7P0Z4D3|A0A7P0Z4D3_HUMAN" 3 1310.7433 0.98 17309 17959 2 1310.743799 656.3789 Transportin-1 OS=Homo sapiens OX=9606 GN=TNPO1 PE=1 SV=2 5.66 3257.6 - 2.00E+06 - - - 0.354 - 2.888 0.288 - 678 1 2 0 0.0005 12 0 0 0 4.48E+07 4.56E+07 - - - 3.9585 0.9971 221125_WJC_METTL3_EV_vs_WT_F02.17961.17961.2 0.738 14-Aug R.DIQTLLSR.M "sp|P46379|BAG6_HUMAN,tr|F6UR09|F6UR09_HUMAN,tr|A0A7I2V508|A0A7I2V508_HUMAN,tr|F6U1F2|F6U1F2_HUMAN,tr|F6U341|F6U341_HUMAN,tr|F6WML8|F6WML8_HUMAN,tr|A0A0G2JJM1|A0A0G2JJM1_HUMAN,tr|X6REW1|X6REW1_HUMAN,tr|A0A7I2V3H1|A0A7I2V3H1_HUMAN,tr|A0A7P0MQS5|A0A7P0MQS5_HUMAN,tr|F6XTU0|F6XTU0_HUMAN,tr|F6X9W3|F6X9W3_HUMAN,tr|F6VEM6|F6VEM6_HUMAN,tr|A0A0G2JJR8|A0A0G2JJR8_HUMAN,tr|F6S6P2|F6S6P2_HUMAN,tr|A0A0G2JL47|A0A0G2JL47_HUMAN,tr|A0A024RCR6|A0A024RCR6_HUMAN,tr|A0A0G2JK23|A0A0G2JK23_HUMAN,tr|A0A1B0GX79|A0A1B0GX79_HUMAN" 19 944.5291 1.21 17311 17961 2 944.528507 473.2718 Large proline-rich protein BAG6 OS=Homo sapiens OX=9606 GN=BAG6 PE=1 SV=2 5.84 3257.8 - 2.00E+06 - - - -0.6225 - 1.458 0.185 - 234.9 1 2 0 -0.0006 8 0 0 0 1.60E+08 1.32E+08 - - - 1.5444 0.9945 221125_WJC_METTL3_EV_vs_WT_F02.17963.17963.2 0.882 14-Sep R.DIQTLLSR[166.11].M "sp|P46379|BAG6_HUMAN,tr|F6UR09|F6UR09_HUMAN,tr|A0A7I2V508|A0A7I2V508_HUMAN,tr|F6U1F2|F6U1F2_HUMAN,tr|F6U341|F6U341_HUMAN,tr|F6WML8|F6WML8_HUMAN,tr|A0A0G2JJM1|A0A0G2JJM1_HUMAN,tr|X6REW1|X6REW1_HUMAN,tr|A0A7I2V3H1|A0A7I2V3H1_HUMAN,tr|A0A7P0MQS5|A0A7P0MQS5_HUMAN,tr|F6XTU0|F6XTU0_HUMAN,tr|F6X9W3|F6X9W3_HUMAN,tr|F6VEM6|F6VEM6_HUMAN,tr|A0A0G2JJR8|A0A0G2JJR8_HUMAN,tr|F6S6P2|F6S6P2_HUMAN,tr|A0A0G2JL47|A0A0G2JL47_HUMAN,tr|A0A024RCR6|A0A024RCR6_HUMAN,tr|A0A0G2JK23|A0A0G2JK23_HUMAN,tr|A0A1B0GX79|A0A1B0GX79_HUMAN" 19 954.5374 1.21 17313 17963 2 954.535165 478.276 Large proline-rich protein BAG6 OS=Homo sapiens OX=9606 GN=BAG6 PE=1 SV=2 5.84 3258 - 1.67E+06 - - - -2.3048 - 1.591 0.18 - 295.5 1 2 0 -0.0022 8 0 0 0 1.60E+08 1.32E+08 - - - 1.7703 0.999 221125_WJC_METTL3_EV_vs_WT_F02.17964.17964.2 0.000104 20-Nov K.DAAFATLVSDR.F "sp|Q9BW27|NUP85_HUMAN,tr|J3QLH0|J3QLH0_HUMAN,tr|J3KT10|J3KT10_HUMAN,tr|F5H0W7|F5H0W7_HUMAN,tr|J3QL54|J3QL54_HUMAN" 5 1164.5775 463.84 17314 17964 2 1164.574867 583.296 Nuclear pore complex protein Nup85 OS=Homo sapiens OX=9606 GN=NUP85 PE=1 SV=1 4.21 3258.1 - 1.44E+06 - - - -2.2626 - 2.107 0.301 - 320.2 1 2 0 -0.0026 11 0 0 0 1.38E+08 2.96E+05 - - - 3.2795 0.9953 221125_WJC_METTL3_EV_vs_WT_F02.17966.17966.2 0.0428 14-Aug K.GYGFGLIK[136.11].L "sp|P21796|VDAC1_HUMAN,tr|C9JI87|C9JI87_HUMAN" 2 861.484 1.18 17316 17966 2 861.48229 431.7493 Voltage-dependent anion-selective channel protein 1 OS=Homo sapiens OX=9606 GN=VDAC1 PE=1 SV=2 8.59 3258.4 - 918933 - - - -1.9733 - 1.171 0.296 - 172.4 1 2 0 -0.0017 8 0 0 0 1.12E+07 9.51E+06 - - - 1.7028 0.9988 221125_WJC_METTL3_EV_vs_WT_F02.17967.17967.2 1.26E-06 24-Nov R.LVQSPNSYFMDVK[136.11].C "sp|Q71UM5|RS27L_HUMAN,sp|P42677|RS27_HUMAN,tr|H0YMV8|H0YMV8_HUMAN,tr|C9JLI6|C9JLI6_HUMAN" 4 1534.7581 0.4 17317 17967 2 1534.751202 768.3863 40S ribosomal protein S27-like OS=Homo sapiens OX=9606 GN=RPS27L PE=1 SV=3 5.83 3258.5 - 840669 - - - -4.5049 - 2.439 0.564 - 369.7 1 2 0 -0.0069 13 0 0 0 4.90E+08 1.24E+09 - - - 5.4928 0.9996 221125_WJC_METTL3_EV_vs_WT_F02.17969.17969.2 0.00681 13/22 K.AIC[160.03]TEAGLMALR[166.11].E sp|P62191|PRS4_HUMAN 1 1314.6663 1.86 17319 17969 2 1314.665956 658.3405 26S proteasome regulatory subunit 4 OS=Homo sapiens OX=9606 GN=PSMC1 PE=1 SV=1 6.04 3258.8 - 638034 - - - -0.2982 - 1.858 0.346 - 597.3 1 2 0 -0.0004 12 0 0 0 1.59E+07 8.54E+06 - - - 3.2264 0.9794 221125_WJC_METTL3_EV_vs_WT_F02.17972.17972.3 0.0333 Nov-36 K.FAAQELIEVK[136.11].R "sp|Q86U44|MTA70_HUMAN,tr|F5H6D8|F5H6D8_HUMAN,tr|H0YFV6|H0YFV6_HUMAN,tr|B4DTN4|B4DTN4_HUMAN" 4 1154.6427 0.01 17321 17972 3 1154.637954 385.8882 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 4.53 3259.1 - 1.78E+06 - - - -4.0887 - 1.774 0.221 - 162.6 1 2 0 -0.0047 10 0 0 0 1.48E+07 2.40E+09 - - - 2.6767 0.9988 221125_WJC_METTL3_EV_vs_WT_F02.17974.17974.2 0.014 16-Aug R.ALPEFFNGK.N "sp|Q8TAQ2|SMRC2_HUMAN,sp|Q92922|SMRC1_HUMAN,tr|F8VXC8|F8VXC8_HUMAN" 3 1021.5233 3.27 17323 17974 2 1021.52174 511.7689 SWI\SNF complex subunit SMARCC2 OS=Homo sapiens OX=9606 GN=SMARCC2 PE=1 SV=1 6.05 3259.1 - 1.14E+07 - - - -1.5095 - 1.629 0.288 - 275.2 1 2 0 -0.0015 9 0 0 0 2.00E+08 6.13E+07 - - - 2.5794 0.9999 221125_WJC_METTL3_EV_vs_WT_F02.17975.17975.2 9.04E-06 18-Nov K.FAAQELIEVK.R "sp|Q86U44|MTA70_HUMAN,tr|F5H6D8|F5H6D8_HUMAN,tr|H0YFV6|H0YFV6_HUMAN,tr|B4DTN4|B4DTN4_HUMAN" 4 1146.6285 0.03 17324 17975 2 1146.629458 574.3215 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 4.53 3259.2 - 1.02E+07 - - - 0.8573 - 2.238 0.526 - 321.2 1 2 0 0.001 10 0 0 0 2.86E+10 8.50E+11 - - - 5.1744 0.9999 221125_WJC_METTL3_EV_vs_WT_F02.17976.17976.2 2.98E-05 18-Sep K.FGFGFGGTGK[136.11].K "sp|Q92499|DDX1_HUMAN,tr|A0A7I2V2M5|A0A7I2V2M5_HUMAN,tr|A0A7I2V430|A0A7I2V430_HUMAN,tr|A0A7I2V421|A0A7I2V421_HUMAN,tr|A0A7I2V4F0|A0A7I2V4F0_HUMAN,tr|A0A7I2V5X8|A0A7I2V5X8_HUMAN,tr|A0A7I2V4J3|A0A7I2V4J3_HUMAN,tr|A0A087WZ71|A0A087WZ71_HUMAN,tr|A0A7I2YQ77|A0A7I2YQ77_HUMAN" 9 981.48 1.48 17325 17976 2 981.479968 491.7473 ATP-dependent RNA helicase DDX1 OS=Homo sapiens OX=9606 GN=DDX1 PE=1 SV=2 8.75 3259.3 - 3.95E+06 - - - 0.001 - 1.925 0.492 - 148.2 1 2 0 0 10 0 0 0 1.21E+08 8.13E+07 - - - 4.503 0.9993 221125_WJC_METTL3_EV_vs_WT_F02.17977.17977.2 0.1 16-Oct K.QELLEALTK.H "sp|P12956|XRCC6_HUMAN,tr|B1AHC9|B1AHC9_HUMAN" 2 1043.5863 1.18 17326 17977 2 1043.58708 522.8004 X-ray repair cross-complementing protein 6 OS=Homo sapiens OX=9606 GN=XRCC6 PE=1 SV=2 4.53 3259.3 - 3.35E+06 - - - 0.7704 - 1.955 0.249 - 317.5 1 2 0 0.0008 9 0 0 0 7.24E+07 6.14E+07 - - - 2.8193 0.9995 221125_WJC_METTL3_EV_vs_WT_F02.17978.17978.2 0.0147 18-Sep R.EGETMILTLK.D sp|O43290|SNUT1_HUMAN 1 1133.6002 0.72 17327 17978 2 1133.598956 567.8074 U4\U6.U5 tri-snRNP-associated protein 1 OS=Homo sapiens OX=9606 GN=SART1 PE=1 SV=1 4.53 3259.4 - 3.06E+06 - - - -1.1071 - 1.913 0.328 - 257.8 1 2 0 -0.0013 10 0 0 0 4.47E+07 6.22E+07 - - - 3.2739 0.9998 221125_WJC_METTL3_EV_vs_WT_F02.17980.17980.2 0.0466 22-Dec K.TLLENTAITIGR.L "sp|Q92973|TNPO1_HUMAN,tr|S4R398|S4R398_HUMAN,tr|A0A7P0Z4D3|A0A7P0Z4D3_HUMAN" 3 1300.7351 0.98 17329 17980 2 1300.7335 651.3748 Transportin-1 OS=Homo sapiens OX=9606 GN=TNPO1 PE=1 SV=2 5.66 3259.6 - 2.33E+06 - - - -1.2032 - 2.746 0.392 - 442.5 1 2 0 -0.0016 12 0 0 0 4.48E+07 4.56E+07 - - - 4.5937 0.9997 221125_WJC_METTL3_EV_vs_WT_F02.17981.17981.2 0.00252 17/24 K.IPGGIIEDSC[160.03]VLR[166.11].G "sp|P49368|TCPG_HUMAN,tr|E9PRC8|E9PRC8_HUMAN,tr|B4DUR8|B4DUR8_HUMAN,tr|E9PQ35|E9PQ35_HUMAN,tr|Q5SZX6|Q5SZX6_HUMAN" 5 1437.7525 0.27 17330 17981 2 1437.749888 719.8835 T-complex protein 1 subunit gamma OS=Homo sapiens OX=9606 GN=CCT3 PE=1 SV=4 4.37 3259.7 - 1.73E+06 - - - -1.8306 - 2.586 0.431 - 1061.8 1 2 0 -0.0026 13 0 0 0 3.36E+08 1.24E+09 - - - 4.662 0.9977 221125_WJC_METTL3_EV_vs_WT_F02.17984.17984.3 0.603 13/36 R.ISNLIVLHLR.K sp|Q14566|MCM6_HUMAN 1 1176.7343 0.55 17333 17984 3 1176.732527 393.252 DNA replication licensing factor MCM6 OS=Homo sapiens OX=9606 GN=MCM6 PE=1 SV=1 9.76 3260.1 - 1.10E+06 - - - -1.488 - 2.084 0.199 - 168.4 1 2 0 -0.0018 10 0 0 0 1.24E+07 2.27E+07 - - - 2.9026 0.9665 221125_WJC_METTL3_EV_vs_WT_F02.17985.17985.2 0.25 14-Jul K.GYGFGLIK.L "sp|P21796|VDAC1_HUMAN,tr|C9JI87|C9JI87_HUMAN" 2 853.4698 1.19 17334 17985 2 853.467214 427.7422 Voltage-dependent anion-selective channel protein 1 OS=Homo sapiens OX=9606 GN=VDAC1 PE=1 SV=2 8.59 3260.2 - 1.01E+06 - - - -3.0183 - 1.112 0.196 - 129.4 1 2 0 -0.0026 8 0 0 0 1.13E+07 9.51E+06 - - - 0.808 0.9081 221125_WJC_METTL3_EV_vs_WT_F02.17986.17986.2 0.0246 14-Sep K.DLTEYLSR[166.11].F "sp|O14979|HNRDL_HUMAN,tr|A0A087WUK2|A0A087WUK2_HUMAN" 2 1005.5006 1.39 17335 17986 2 1005.496255 503.7576 Heterogeneous nuclear ribonucleoprotein D-like OS=Homo sapiens OX=9606 GN=HNRNPDL PE=1 SV=3 4.37 3260.4 - 995016 - - - -4.366 - 1.565 0.049 - 307.9 1 2 0 -0.0044 8 0 0 0 5.27E+08 3.80E+08 - - - 0.7523 0.9977 221125_WJC_METTL3_EV_vs_WT_F02.17993.17993.2 0.0353 16-Oct K.QVEEIFNLK.F "sp|P78347|GTF2I_HUMAN,tr|A0A494C0Q7|A0A494C0Q7_HUMAN,tr|A0A494C1K3|A0A494C1K3_HUMAN" 3 1118.5972 1.49 17340 17993 2 1118.596151 560.3059 General transcription factor II-I OS=Homo sapiens OX=9606 GN=GTF2I PE=1 SV=2 4.53 3261.3 - 9.09E+06 - - - -0.9154 - 1.611 0.184 - 237.6 1 2 0 -0.001 9 0 0 0 1.22E+09 8.22E+08 - - - 1.7793 0.9999 221125_WJC_METTL3_EV_vs_WT_F02.17994.17994.2 0.000514 18-Nov K.FGFGFGGTGK.K "sp|Q92499|DDX1_HUMAN,tr|A0A7I2V2M5|A0A7I2V2M5_HUMAN,tr|A0A7I2V430|A0A7I2V430_HUMAN,tr|A0A7I2V421|A0A7I2V421_HUMAN,tr|A0A7I2V4F0|A0A7I2V4F0_HUMAN,tr|A0A7I2V5X8|A0A7I2V5X8_HUMAN,tr|A0A7I2V4J3|A0A7I2V4J3_HUMAN,tr|A0A087WZ71|A0A087WZ71_HUMAN,tr|A0A7I2YQ77|A0A7I2YQ77_HUMAN" 9 973.4658 1.49 17341 17994 2 973.464799 487.7402 ATP-dependent RNA helicase DDX1 OS=Homo sapiens OX=9606 GN=DDX1 PE=1 SV=2 8.75 3261.3 - 7.52E+06 - - - -0.9944 - 2.246 0.499 - 247.5 1 2 0 -0.001 10 0 0 0 1.21E+08 8.13E+07 - - - 4.9849 0.9914 221125_WJC_METTL3_EV_vs_WT_F02.17995.17995.2 0.0109 16-Aug K.QVEEIFNLK[136.11].F "sp|P78347|GTF2I_HUMAN,tr|A0A494C0Q7|A0A494C0Q7_HUMAN,tr|A0A494C1K3|A0A494C1K3_HUMAN" 3 1126.6114 1.5 17342 17995 2 1126.613011 564.313 General transcription factor II-I OS=Homo sapiens OX=9606 GN=GTF2I PE=1 SV=2 4.53 3261.4 - 7.19E+06 - - - 1.4521 - 1.711 0.066 - 277.6 1 2 0 0.0016 9 0 0 0 1.23E+09 8.23E+08 - - - 1.0818 0.9997 221125_WJC_METTL3_EV_vs_WT_F02.17996.17996.2 0.000619 16-Aug K.GLIDYETFK.E sp|P15924|DESP_HUMAN 1 1084.5441 14.65 17343 17996 2 1084.543683 543.2793 Desmoplakin OS=Homo sapiens OX=9606 GN=DSP PE=1 SV=3 4.37 3261.4 - 4.35E+06 - - - -0.3633 - 1.518 0.458 - 171.5 1 2 0 -0.0004 9 0 0 0 1.13E+08 7.72E+06 - - - 3.6312 0.9998 221125_WJC_METTL3_EV_vs_WT_F02.18000.18000.2 4.67E-05 13/24 R.LESLSYQLSGLQK.Q sp|Q03252|LMNB2_HUMAN 1 1464.7824 1.47 17347 18000 2 1464.779721 733.3985 Lamin-B2 OS=Homo sapiens OX=9606 GN=LMNB2 PE=1 SV=4 6 3261.8 - 962154 - - - -1.8358 - 2.524 0.499 - 409.9 1 2 0 -0.0027 13 0 0 0 5.13E+07 3.49E+07 - - - 5.102 0.9999 221125_WJC_METTL3_EV_vs_WT_F02.18003.18003.2 0.000181 14/24 K.IPGGIIEDSC[160.03]VLR.G "sp|P49368|TCPG_HUMAN,tr|E9PRC8|E9PRC8_HUMAN,tr|B4DUR8|B4DUR8_HUMAN,tr|E9PQ35|E9PQ35_HUMAN,tr|Q5SZX6|Q5SZX6_HUMAN" 5 1427.7442 0.27 17348 18003 2 1427.744035 714.8794 T-complex protein 1 subunit gamma OS=Homo sapiens OX=9606 GN=CCT3 PE=1 SV=4 4.37 3262.2 - 2.55E+06 - - - -0.1506 - 2.6 0.416 - 793 1 2 0 -0.0002 13 0 0 0 3.64E+08 1.34E+09 - - - 4.5659 1 221125_WJC_METTL3_EV_vs_WT_F02.18005.18005.2 2.78E-08 15/24 R.LVQSPNSYFMDVK.C "sp|Q71UM5|RS27L_HUMAN,sp|P42677|RS27_HUMAN,tr|H0YMV8|H0YMV8_HUMAN,tr|C9JLI6|C9JLI6_HUMAN" 4 1526.7439 0.4 17350 18005 2 1526.744854 764.3792 40S ribosomal protein S27-like OS=Homo sapiens OX=9606 GN=RPS27L PE=1 SV=3 5.83 3262.4 - 1.72E+06 - - - 0.6144 - 2.703 0.575 - 752.8 1 2 0 0.0009 13 0 0 0 4.90E+08 1.24E+09 - - - 5.8397 1 221125_WJC_METTL3_EV_vs_WT_F02.18007.18007.2 9.52E-06 14/26 K.LGNGINIIVATPGR[166.11].L sp|Q9NVP1|DDX18_HUMAN 1 1403.8124 0.92 17352 18007 2 1403.819189 702.9135 ATP-dependent RNA helicase DDX18 OS=Homo sapiens OX=9606 GN=DDX18 PE=1 SV=2 9.75 3262.6 - 835467 - - - 4.8233 - 3.013 0.534 - 750.5 1 2 0 0.0068 14 0 0 0 2.14E+07 2.32E+07 - - - 5.7508 0.9992 221125_WJC_METTL3_EV_vs_WT_F02.18008.18008.2 0.0096 24-Sep K.LLASTTPEEILEK[136.11].L "sp|Q8WUR7|CO040_HUMAN,tr|H3BQZ5|H3BQZ5_HUMAN" 2 1450.801 0.21 17353 18008 2 1450.801848 726.4078 UPF0235 protein C15orf40 OS=Homo sapiens OX=9606 GN=C15orf40 PE=1 SV=2 4.25 3262.8 - 591051 - - - 0.5666 - 1.746 0.298 - 153.9 1 2 0 0.0008 13 0 0 0 4.32E+06 2.04E+07 - - - 2.6722 0.9993 221125_WJC_METTL3_EV_vs_WT_F02.18012.18012.2 0.00184 16-Sep K.FGLFTPGSR[166.11].L "sp|P36551|HEM6_HUMAN,tr|H0YA22|H0YA22_HUMAN" 2 990.5162 0.81 17355 18012 2 990.514312 496.2654 "Oxygen-dependent coproporphyrinogen-III oxidase, mitochondrial OS=Homo sapiens OX=9606 GN=CPOX PE=1 SV=3" 9.75 3263.3 - 1.54E+06 - - - -1.9424 - 1.755 0.368 - 202.9 1 2 0 -0.0019 9 0 0 0 2.04E+07 2.52E+07 - - - 3.3857 0.9997 221125_WJC_METTL3_EV_vs_WT_F02.18013.18013.2 6.34E-06 15/26 K.LGNGINIIVATPGR.L sp|Q9NVP1|DDX18_HUMAN 1 1393.8041 0.92 17356 18013 2 1393.800639 697.9094 ATP-dependent RNA helicase DDX18 OS=Homo sapiens OX=9606 GN=DDX18 PE=1 SV=2 9.75 3263.4 - 996465 - - - -2.5176 - 2.497 0.533 - 667 1 2 0 -0.0035 14 0 0 0 2.14E+07 2.32E+07 - - - 5.273 0.8162 221125_WJC_METTL3_EV_vs_WT_F02.18018.18018.2 0.0407 14-Aug R.SINQPVAF.V "sp|Q9GZT3|SLIRP_HUMAN,tr|A0A087WUN7|A0A087WUN7_HUMAN,tr|H0YJI1|H0YJI1_HUMAN,tr|G3V2S9|G3V2S9_HUMAN,tr|H0YJ40|H0YJ40_HUMAN,tr|G3V4X6|G3V4X6_HUMAN" 6 874.4549 - 17361 18018 2 874.454192 438.2347 "SRA stem-loop-interacting RNA-binding protein, mitochondrial OS=Homo sapiens OX=9606 GN=SLIRP PE=1 SV=1" 5.24 3264 - 739443 - - - -0.7731 - 1.248 0.227 - 156.5 1 1 0 -0.0007 8 0 0 0 - - - - - 1.3856 0.9623 221125_WJC_METTL3_EV_vs_WT_F02.18021.18021.3 0.153 Sep-48 K.LK[136.11]EVFSMAGVVVR[166.11].A "sp|P52272|HNRPM_HUMAN,tr|M0R019|M0R019_HUMAN,tr|M0R0N3|M0R0N3_HUMAN,tr|A0A087X0X3|A0A087X0X3_HUMAN,tr|M0QZM1|M0QZM1_HUMAN,tr|M0QYQ7|M0QYQ7_HUMAN,tr|M0R2T0|M0R2T0_HUMAN" 7 1451.8289 1.81 17362 18021 3 1451.828696 484.9503 Heterogeneous nuclear ribonucleoprotein M OS=Homo sapiens OX=9606 GN=HNRNPM PE=1 SV=3 8.75 3264.4 - 1.50E+06 - - - -0.1584 - 1.765 0.164 - 111.5 1 2 1 -0.0002 13 0 0 0 3.59E+07 1.98E+07 - - - 1.9088 0.9971 221125_WJC_METTL3_EV_vs_WT_F02.18023.18023.2 0.647 16-Oct K.QELLEALTK[136.11].H "sp|P12956|XRCC6_HUMAN,tr|B1AHC9|B1AHC9_HUMAN" 2 1051.6005 1.27 17364 18023 2 1051.601681 526.8075 X-ray repair cross-complementing protein 6 OS=Homo sapiens OX=9606 GN=XRCC6 PE=1 SV=2 4.53 3264.6 - 2.48E+06 - - - 1.1459 - 1.722 0.156 - 281.3 1 2 0 0.0012 9 0 0 0 7.28E+07 5.74E+07 - - - 1.7652 1 221125_WJC_METTL3_EV_vs_WT_F02.18024.18024.3 8.50E-08 16/48 K.IPGGIIEDSC[160.03]VLR[166.11].G "sp|P49368|TCPG_HUMAN,tr|E9PRC8|E9PRC8_HUMAN,tr|B4DUR8|B4DUR8_HUMAN,tr|E9PQ35|E9PQ35_HUMAN,tr|Q5SZX6|Q5SZX6_HUMAN" 5 1437.7525 0.22 17365 18024 3 1437.750798 480.2581 T-complex protein 1 subunit gamma OS=Homo sapiens OX=9606 GN=CCT3 PE=1 SV=4 4.37 3264.7 - 3.07E+06 - - - -1.1977 - 2.632 0.539 - 407.7 1 2 0 -0.0017 13 0 0 0 1.14E+07 5.22E+07 - - - 7.1727 1 221125_WJC_METTL3_EV_vs_WT_F02.18025.18025.2 2.34E-08 13/24 R.IVESDVGDSFYIR.T "sp|Q07157|ZO1_HUMAN,tr|A0A087X0K9|A0A087X0K9_HUMAN,tr|G5E9E7|G5E9E7_HUMAN,tr|A0A0G2JNH2|A0A0G2JNH2_HUMAN,tr|G3V1L9|G3V1L9_HUMAN,tr|A0A7I2V5U5|A0A7I2V5U5_HUMAN" 6 1498.7304 0.68 17366 18025 2 1498.730335 750.3725 Tight junction protein ZO-1 OS=Homo sapiens OX=9606 GN=TJP1 PE=1 SV=3 4.03 3264.8 - 647365 - - - -0.026 - 2.53 0.622 - 495.3 1 2 0 0 13 0 0 0 1.39E+07 2.05E+07 - - - 6.0174 0.9238 221125_WJC_METTL3_EV_vs_WT_F02.18029.18029.2 0.0747 14-Jun K.DLTEYLSR.F "sp|O14979|HNRDL_HUMAN,tr|A0A087WUK2|A0A087WUK2_HUMAN" 2 995.4924 1.37 17368 18029 2 995.490558 498.7535 Heterogeneous nuclear ribonucleoprotein D-like OS=Homo sapiens OX=9606 GN=HNRNPDL PE=1 SV=3 4.37 3265.4 - 2.85E+07 - - - -1.8252 - 1.246 0.016 - 123.2 2 2 0 -0.0018 8 0 0 0 5.19E+08 3.80E+08 - - - -0.3125 0.9999 221125_WJC_METTL3_EV_vs_WT_F02.18030.18030.2 3.25E-05 16-Oct K.FEDENFILK[136.11].H "sp|P62937|PPIA_HUMAN,tr|C9J5S7|C9J5S7_HUMAN,tr|A0A7I2V4V1|A0A7I2V4V1_HUMAN,tr|F8WE65|F8WE65_HUMAN" 4 1161.5797 0.82 17369 18030 2 1161.578431 581.7971 Peptidyl-prolyl cis-trans isomerase A OS=Homo sapiens OX=9606 GN=PPIA PE=1 SV=2 4.14 3265.4 - 1.69E+07 - - - -1.1269 - 1.848 0.555 - 166.6 1 2 0 -0.0013 9 0 0 0 2.69E+08 3.30E+08 - - - 4.9165 0.9999 221125_WJC_METTL3_EV_vs_WT_F02.18038.18038.2 1.48E-05 16-Nov R.VFSLSSEFK.N "sp|O75643|U520_HUMAN,tr|A0A494C1A5|A0A494C1A5_HUMAN" 2 1042.5335 1.84 17375 18038 2 1042.532912 522.274 U5 small nuclear ribonucleoprotein 200 kDa helicase OS=Homo sapiens OX=9606 GN=SNRNP200 PE=1 SV=2 5.97 3266.4 - 4.71E+06 - - - -0.5755 - 2.049 0.513 - 391.5 1 2 0 -0.0006 9 0 0 0 2.10E+08 1.14E+08 - - - 4.9052 0.9998 221125_WJC_METTL3_EV_vs_WT_F02.18039.18039.2 0.00994 16-Sep R.VFSLSSEFK[136.11].N "sp|O75643|U520_HUMAN,tr|A0A494C1A5|A0A494C1A5_HUMAN" 2 1050.5477 1.84 17376 18039 2 1050.548259 526.2811 U5 small nuclear ribonucleoprotein 200 kDa helicase OS=Homo sapiens OX=9606 GN=SNRNP200 PE=1 SV=2 5.97 3266.5 - 2.93E+06 - - - 0.5207 - 1.848 0.424 - 226 1 2 0 0.0005 9 0 0 0 2.10E+08 1.14E+08 - - - 3.9491 0.9999 221125_WJC_METTL3_EV_vs_WT_F02.18040.18040.2 8.70E-06 13/24 R.LALPQSDASLLSR.D "sp|Q9H583|HEAT1_HUMAN,tr|Q6P664|Q6P664_HUMAN,tr|Q5T3Q7|Q5T3Q7_HUMAN" 3 1369.7565 1.87 17377 18040 2 1369.756933 685.8855 HEAT repeat-containing protein 1 OS=Homo sapiens OX=9606 GN=HEATR1 PE=1 SV=3 5.84 3266.6 - 3.74E+06 - - - 0.2949 - 2.179 0.492 - 637.1 1 2 0 0.0004 13 0 0 0 6.03E+07 3.23E+07 - - - 4.6738 0.9607 221125_WJC_METTL3_EV_vs_WT_F02.18043.18043.2 1.13 24-Jul K.SFPPPGPAEGLLR.Q "sp|P54105|ICLN_HUMAN,tr|E9PJF4|E9PJF4_HUMAN,tr|J3KN38|J3KN38_HUMAN,tr|E9PMI6|E9PMI6_HUMAN,tr|E9PQ83|E9PQ83_HUMAN" 5 1336.7139 10.68 17380 18043 2 1336.716658 669.3642 Methylosome subunit pICln OS=Homo sapiens OX=9606 GN=CLNS1A PE=1 SV=1 5.72 3266.9 - 1.40E+06 - - - 2.0363 - 1.286 0.115 - 74.6 4 2 0 0.0027 13 0 0 0 3.52E+07 3.29E+06 - - - 0.2662 0.9992 221125_WJC_METTL3_EV_vs_WT_F02.18044.18044.2 0.00538 16-Nov K.DILTSVVSR.R sp|Q96BN2|TADA1_HUMAN 1 988.5553 1.09 17381 18044 2 988.556346 495.2849 Transcriptional adapter 1 OS=Homo sapiens OX=9606 GN=TADA1 PE=1 SV=1 5.84 3267 - 1.19E+06 - - - 1.048 - 1.766 0.293 - 355 1 2 0 0.001 9 0 0 0 4.48E+07 4.12E+07 - - - 2.8501 0.9991 221125_WJC_METTL3_EV_vs_WT_F02.18048.18048.2 0.00923 18-Nov K.QLAVYEEFAR[166.11].N sp|A5YKK6|CNOT1_HUMAN 1 1234.6222 8.87 17385 18048 2 1234.622136 618.3184 CCR4-NOT transcription complex subunit 1 OS=Homo sapiens OX=9606 GN=CNOT1 PE=1 SV=2 4.53 3267.5 - 810954 - - - -0.0178 - 2.151 0.169 - 479.1 1 2 0 0 10 0 0 0 1.73E+08 1.95E+07 - - - 2.4272 0.9117 221125_WJC_METTL3_EV_vs_WT_F02.18049.18049.2 6.6 20-Jul R.FAELAQIYAQR.G "sp|Q9NQR4|NIT2_HUMAN,tr|H7C579|H7C579_HUMAN" 2 1308.6826 0.43 17386 18049 2 1308.684242 655.3486 Omega-amidase NIT2 OS=Homo sapiens OX=9606 GN=NIT2 PE=1 SV=1 6 3267.6 - 773746 - - - 1.2272 - 1.248 0.026 - 106.9 8 2 0 0.0016 11 0 0 0 2.59E+07 6.00E+07 - - - -0.5716 0.9985 221125_WJC_METTL3_EV_vs_WT_F02.18050.18050.2 0.0294 16-Sep R.NMDIAMGWK[136.11].G "sp|Q7L0Y3|TM10C_HUMAN,tr|C9JVB6|C9JVB6_HUMAN" 2 1072.4925 0.79 17387 18050 2 1072.489098 537.2535 tRNA methyltransferase 10 homolog C OS=Homo sapiens OX=9606 GN=TRMT10C PE=1 SV=2 5.84 3267.8 - 550738 - - - -3.1926 - 1.908 0.361 - 262 1 2 0 -0.0034 9 0 0 0 7.10E+06 8.99E+06 - - - 3.5753 0.9866 221125_WJC_METTL3_EV_vs_WT_F02.18060.18060.2 0.909 14-Aug K.TQLYGFLK.E "sp|Q8IWJ2|GCC2_HUMAN,tr|B8ZZW2|B8ZZW2_HUMAN" 2 968.5331 1.12 17395 18060 2 968.533978 485.2738 GRIP and coiled-coil domain-containing protein 2 OS=Homo sapiens OX=9606 GN=GCC2 PE=1 SV=4 8.26 3269 - 774792 - - - 0.8879 - 1.388 0.074 - 201.9 1 2 0 0.0009 8 0 0 0 1.04E+07 9.25E+06 - - - 0.5761 0.9997 221125_WJC_METTL3_EV_vs_WT_F02.18064.18064.2 6.04E-05 13/24 K.FLPGMAIGYSSSK[136.11].L "sp|P19623|SPEE_HUMAN,tr|K7EQ47|K7EQ47_HUMAN" 2 1364.689 0.38 17399 18064 2 1364.69083 683.3518 Spermidine synthase OS=Homo sapiens OX=9606 GN=SRM PE=1 SV=1 8.59 3269.5 - 554886 - - - 1.3607 - 2.042 0.444 - 558 1 2 0 0.0019 13 0 0 0 1.18E+07 3.06E+07 - - - 4.1521 1 221125_WJC_METTL3_EV_vs_WT_F02.18068.18068.3 9.40E-06 15/48 R.RLLYMAIDGVAPR.A sp|Q9H0D6|XRN2_HUMAN 1 1473.8126 0.91 17401 18068 3 1473.812085 492.2781 5'-3' exoribonuclease 2 OS=Homo sapiens OX=9606 GN=XRN2 PE=1 SV=1 8.75 3270 - 3.47E+06 - - - -0.3521 - 2.853 0.492 - 403.3 1 2 0 -0.0005 13 0 0 0 4.30E+07 4.70E+07 - - - 6.8676 0.9989 221125_WJC_METTL3_EV_vs_WT_F02.18070.18070.3 0.0234 Dec-48 R.LVQSPNSYFMDVK.C "sp|Q71UM5|RS27L_HUMAN,sp|P42677|RS27_HUMAN,tr|H0YMV8|H0YMV8_HUMAN,tr|C9JLI6|C9JLI6_HUMAN" 4 1526.7439 0.34 17403 18070 3 1526.742339 509.9219 40S ribosomal protein S27-like OS=Homo sapiens OX=9606 GN=RPS27L PE=1 SV=3 5.83 3270.2 - 1.07E+06 - - - -1.0329 - 1.744 0.285 - 154.3 1 2 0 -0.0016 13 0 0 0 1.31E+07 3.90E+07 - - - 3.225 0.9988 221125_WJC_METTL3_EV_vs_WT_F02.18072.18072.2 0.0337 14-Sep R.QQILLSFK.T sp|P50995|ANX11_HUMAN 1 975.5753 1.22 17405 18072 2 975.576849 488.7949 Annexin A11 OS=Homo sapiens OX=9606 GN=ANXA11 PE=1 SV=1 8.75 3270.5 - 938819 - - - 1.5704 - 1.604 0.308 - 248.7 1 2 0 0.0015 8 0 0 0 1.57E+07 1.29E+07 - - - 2.7404 0.9995 221125_WJC_METTL3_EV_vs_WT_F02.18073.18073.2 0.000619 16-Sep K.QETTFLAFK[136.11].R "sp|Q96CB8|INT12_HUMAN,tr|A0A087WXN4|A0A087WXN4_HUMAN" 2 1091.5743 0.69 17406 18073 2 1091.573526 546.7944 Integrator complex subunit 12 OS=Homo sapiens OX=9606 GN=INTS12 PE=1 SV=1 6 3270.6 - 650799 - - - -0.6733 - 1.61 0.366 - 185.6 1 2 0 -0.0007 9 0 0 0 9.56E+06 1.39E+07 - - - 3.1218 0.9995 221125_WJC_METTL3_EV_vs_WT_F02.18079.18079.2 0.00209 14-Aug R.SSFDLLPR.E sp|O94864|ST65G_HUMAN 1 933.492 0.9 17410 18079 2 933.491622 467.7533 STAGA complex 65 subunit gamma OS=Homo sapiens OX=9606 GN=SUPT7L PE=1 SV=1 5.55 3271.4 - 1.36E+06 - - - -0.3856 - 1.465 0.389 - 204.6 1 2 0 -0.0004 8 0 0 0 3.22E+07 3.56E+07 - - - 3.0657 0.9983 221125_WJC_METTL3_EV_vs_WT_F02.18080.18080.2 1.05E-05 24-Dec R.NMPQADAMVLVAR.N sp|Q9HCD5|NCOA5_HUMAN 1 1414.7061 1.63 17411 18080 2 1414.700477 708.3603 Nuclear receptor coactivator 5 OS=Homo sapiens OX=9606 GN=NCOA5 PE=1 SV=2 5.84 3271.4 - 2.99E+06 - - - -3.9676 - 1.835 0.484 - 457.1 1 2 0 -0.0056 13 0 0 0 7.43E+07 4.57E+07 - - - 4.1721 0.9993 221125_WJC_METTL3_EV_vs_WT_F02.18081.18081.3 0.00305 Nov-48 R.LVQSPNSYFMDVK[136.11].C "sp|Q71UM5|RS27L_HUMAN,sp|P42677|RS27_HUMAN,tr|H0YMV8|H0YMV8_HUMAN,tr|C9JLI6|C9JLI6_HUMAN" 4 1534.7581 0.34 17412 18081 3 1534.75951 512.5933 40S ribosomal protein S27-like OS=Homo sapiens OX=9606 GN=RPS27L PE=1 SV=3 5.83 3271.5 - 2.40E+06 - - - 0.9083 - 1.713 0.326 - 174.3 1 2 0 0.0014 13 0 0 0 1.31E+07 3.90E+07 - - - 3.6335 0.9707 221125_WJC_METTL3_EV_vs_WT_F02.18088.18088.2 1.95E-07 13/24 A.VYETDVFVVGTER.G "sp|P78347|GTF2I_HUMAN,sp|Q86UP8|GTD2A_HUMAN,sp|Q6EKJ0|GTD2B_HUMAN,tr|A0A494C1N8|A0A494C1N8_HUMAN,tr|A0A087WW90|A0A087WW90_HUMAN,tr|C9J6M0|C9J6M0_HUMAN,tr|A0A0D9SF80|A0A0D9SF80_HUMAN,tr|A0A494C0I1|A0A494C0I1_HUMAN,tr|A0A494C1K3|A0A494C1K3_HUMAN" 9 1512.746 1.46 17417 18088 2 1512.750768 757.3803 General transcription factor II-I OS=Homo sapiens OX=9606 GN=GTF2I PE=1 SV=2 4.14 3272.4 - 965556 - - - 3.136 - 2.793 0.484 - 591.2 1 1 0 0.0047 13 0 0 0 1.90E+07 1.30E+07 - - - 5.2505 0.9996 221125_WJC_METTL3_EV_vs_WT_F02.18090.18090.2 5.76E-05 16-Oct R.SFDFEIETK.Q sp|Q08945|SSRP1_HUMAN 1 1114.5183 0.63 17419 18090 2 1114.520832 558.2664 FACT complex subunit SSRP1 OS=Homo sapiens OX=9606 GN=SSRP1 PE=1 SV=1 4.14 3272.5 - 908027 - - - 2.3113 - 1.699 0.526 - 280.8 1 2 0 0.0026 9 0 0 0 2.28E+07 3.60E+07 - - - 4.4587 0.9998 221125_WJC_METTL3_EV_vs_WT_F02.18091.18091.2 0.00161 20-Oct K.VSC[160.03]LETVWVSR[166.11].A "sp|Q7L2E3|DHX30_HUMAN,tr|H7BXY3|H7BXY3_HUMAN" 2 1344.6735 0.32 17420 18091 2 1344.671934 673.344 ATP-dependent RNA helicase DHX30 OS=Homo sapiens OX=9606 GN=DHX30 PE=1 SV=1 5.97 3272.7 - 706369 - - - -1.1958 - 2.015 0.438 - 213.4 1 2 0 -0.0016 11 0 0 0 6.83E+06 2.12E+07 - - - 4.1709 0.9999 221125_WJC_METTL3_EV_vs_WT_F02.18097.18097.2 7.64E-06 20-Dec K.GSFADLGLEPR[166.11].V sp|Q9NUL7|DDX28_HUMAN 1 1170.5909 4.32 17424 18097 2 1170.590996 586.3027 Probable ATP-dependent RNA helicase DDX28 OS=Homo sapiens OX=9606 GN=DDX28 PE=1 SV=2 4.37 3273.4 - 3.45E+06 - - - 0.1179 - 2.138 0.52 - 425.6 1 2 0 0.0001 11 0 0 0 2.09E+08 4.83E+07 - - - 4.9373 0.9953 221125_WJC_METTL3_EV_vs_WT_F02.18100.18100.2 0.125 16-Aug K.DILTSVVSR[166.11].R sp|Q96BN2|TADA1_HUMAN 1 998.5636 1.09 17427 18100 2 998.568163 500.2891 Transcriptional adapter 1 OS=Homo sapiens OX=9606 GN=TADA1 PE=1 SV=1 5.84 3273.6 - 1.88E+06 - - - 4.5896 - 1.678 0.4 - 203.7 1 2 0 0.0046 9 0 0 0 4.48E+07 4.12E+07 - - - 3.4914 0.9678 221125_WJC_METTL3_EV_vs_WT_F02.18101.18101.2 0.000114 18-Oct S.SVSFADDFVR.S "sp|P50454|SERPH_HUMAN,tr|E9PNX1|E9PNX1_HUMAN,tr|E9PIG2|E9PIG2_HUMAN,tr|E9PPV6|E9PPV6_HUMAN,tr|E9PR70|E9PR70_HUMAN,tr|E9PMI5|E9PMI5_HUMAN,tr|E9PRS3|E9PRS3_HUMAN,tr|E9PJH8|E9PJH8_HUMAN,tr|E9PK86|E9PK86_HUMAN,tr|E9PQ34|E9PQ34_HUMAN" 10 1141.5404 1.25 17428 18101 2 1141.537386 571.7775 Serpin H1 OS=Homo sapiens OX=9606 GN=SERPINH1 PE=1 SV=2 4.21 3273.7 - 1.53E+06 - - - -2.6298 - 1.738 0.513 - 308.1 1 1 0 -0.003 10 0 0 0 2.09E+07 1.67E+07 - - - 4.3719 0.9473 221125_WJC_METTL3_EV_vs_WT_F02.18102.18102.2 0.00302 24-Oct R.AAVEEGIVLGGGC[160.03].A "sp|P10809|CH60_HUMAN,tr|A0A7I2V2X6|A0A7I2V2X6_HUMAN,tr|A0A7I2YQK6|A0A7I2YQK6_HUMAN,tr|A0A7I2V599|A0A7I2V599_HUMAN" 4 1230.5914 - 17429 18102 2 1230.594473 616.303 "60 kDa heat shock protein, mitochondrial OS=Homo sapiens OX=9606 GN=HSPD1 PE=1 SV=2" 3.79 3273.8 - 1.55E+06 - - - 2.4663 - 1.747 0.424 - 286.1 1 1 0 0.003 13 0 0 0 - - - - - 3.6036 0.9964 221125_WJC_METTL3_EV_vs_WT_F02.18104.18104.3 0.00143 Oct-40 R.MLEDR[166.11]DLFVMR[166.11].L sp|Q14152|EIF3A_HUMAN 1 1443.7117 1.34 17431 18104 3 1443.714671 482.2445 Eukaryotic translation initiation factor 3 subunit A OS=Homo sapiens OX=9606 GN=EIF3A PE=1 SV=1 4.56 3274 - 694850 - - - 2.0364 - 2.069 0.305 - 193 1 2 1 0.0029 11 0 0 0 1.41E+07 1.05E+07 - - - 4.0051 0.9947 221125_WJC_METTL3_EV_vs_WT_F02.18108.18108.2 6.45E-09 15/30 K.AGGYPLVYPGHPLQPA.A sp|Q9H7S9|ZN703_HUMAN 1 1635.8409 - 17435 18108 2 1635.841225 818.9277 Zinc finger protein 703 OS=Homo sapiens OX=9606 GN=ZNF703 PE=1 SV=1 6.78 3274.5 - 483302 - - - 0.1816 - 2.306 0.602 - 471.9 1 1 0 0.0003 16 0 0 0 - - - - - 5.5414 0.9999 221125_WJC_METTL3_EV_vs_WT_F02.18111.18111.2 0.00329 16/24 K.ALIAAQLDNAIEK.E sp|Q9BXY0|MAK16_HUMAN 1 1368.7613 4.53 17436 18111 2 1368.762384 685.3879 Protein MAK16 homolog OS=Homo sapiens OX=9606 GN=MAK16 PE=1 SV=2 4.37 3274.9 - 1.49E+06 - - - 0.8066 - 3.143 0.453 - 902.8 1 2 0 0.0011 13 0 0 0 5.06E+07 1.12E+07 - - - 5.3256 0.9956 221125_WJC_METTL3_EV_vs_WT_F02.18114.18114.2 0.00842 18-Oct R.LETVGSIFSR.T "sp|Q9Y3D9|RT23_HUMAN,tr|J3QLR8|J3QLR8_HUMAN" 2 1107.5924 0.45 17439 18114 2 1107.596649 554.8035 "28S ribosomal protein S23, mitochondrial OS=Homo sapiens OX=9606 GN=MRPS23 PE=1 SV=2" 6 3275.1 - 1.60E+06 - - - 3.8146 - 2.02 0.264 - 320.9 1 2 0 0.0042 10 0 0 0 1.45E+08 3.25E+08 - - - 2.9521 0.9984 221125_WJC_METTL3_EV_vs_WT_F02.18116.18116.2 0.00245 16-Sep K.EITVSFLQK.L sp|O75330|HMMR_HUMAN 1 1063.5914 1.06 17441 18116 2 1063.594022 532.803 Hyaluronan mediated motility receptor OS=Homo sapiens OX=9606 GN=HMMR PE=1 SV=2 6.1 3275.3 - 848812 - - - 2.5019 - 1.626 0.351 - 186 1 2 0 0.0027 9 0 0 0 5.76E+06 5.46E+06 - - - 3.039 0.9998 221125_WJC_METTL3_EV_vs_WT_F02.18117.18117.2 0.00409 20-Nov K.VIVVWNNIGEK[136.11].A "sp|Q9UBQ6|EXTL2_HUMAN,tr|C9IYF5|C9IYF5_HUMAN,tr|F5GZK1|F5GZK1_HUMAN,tr|C9JEG3|C9JEG3_HUMAN" 4 1277.7223 6.82 17442 18117 2 1277.723507 639.8684 Exostosin-like 2 OS=Homo sapiens OX=9606 GN=EXTL2 PE=1 SV=1 5.97 3275.4 - 775160 - - - 0.9274 - 2.275 0.421 - 430.5 1 2 0 0.0012 11 0 0 0 1.17E+08 1.71E+07 - - - 4.3738 1 221125_WJC_METTL3_EV_vs_WT_F02.18119.18119.2 7.40E-07 24-Nov R.FVESVDEYQFVER[166.11].L "sp|Q13405|RM49_HUMAN,tr|E9PNF1|E9PNF1_HUMAN,tr|E9PI78|E9PI78_HUMAN" 3 1655.7707 1.63 17444 18119 2 1655.771832 828.8926 "39S ribosomal protein L49, mitochondrial OS=Homo sapiens OX=9606 GN=MRPL49 PE=1 SV=1" 4 3275.7 - 425193 - - - 0.7006 - 2.661 0.578 - 335.5 1 2 0 0.0012 13 0 0 0 1.58E+07 9.69E+06 - - - 5.8216 1 221125_WJC_METTL3_EV_vs_WT_F02.18120.18120.2 4.89E-10 28-Dec R.AQFFVEDASTASALK[136.11].A "sp|Q9UBU9|NXF1_HUMAN,tr|B4E227|B4E227_HUMAN,tr|E9PLA7|E9PLA7_HUMAN,tr|E9PIN3|E9PIN3_HUMAN" 4 1591.7973 1.18 17445 18120 2 1591.796998 796.9059 Nuclear RNA export factor 1 OS=Homo sapiens OX=9606 GN=NXF1 PE=1 SV=1 4.37 3275.8 - 390903 - - - -0.2136 - 2.421 0.654 - 281.6 1 2 0 -0.0003 15 0 0 0 3.01E+06 2.55E+06 - - - 6.0451 1 221125_WJC_METTL3_EV_vs_WT_F02.18121.18121.2 9.73E-08 14/28 R.AQFFVEDASTASALK.A "sp|Q9UBU9|NXF1_HUMAN,tr|B4E227|B4E227_HUMAN,tr|E9PLA7|E9PLA7_HUMAN,tr|E9PIN3|E9PIN3_HUMAN" 4 1583.7831 1.18 17446 18121 2 1583.783313 792.8988 Nuclear RNA export factor 1 OS=Homo sapiens OX=9606 GN=NXF1 PE=1 SV=1 4.37 3276 - 301954 - - - 0.1105 - 2.924 0.655 - 564.9 1 2 0 0.0002 15 0 0 0 3.01E+06 2.55E+06 - - - 6.5167 0.9997 221125_WJC_METTL3_EV_vs_WT_F02.18127.18127.2 0.00657 20-Oct R.GLSTESILIPR.Q "sp|P31025|LCN1_HUMAN,sp|Q5VSP4|LC1L1_HUMAN" 2 1184.6765 999 17450 18127 2 1184.677688 593.3455 Lipocalin-1 OS=Homo sapiens OX=9606 GN=LCN1 PE=1 SV=1 6 3276.5 - 1.68E+06 - - - 1.0129 - 2.066 0.387 - 440.3 1 2 0 0.0012 11 0 0 0 1.82E+08 0.00E+00 - - - 3.862 0.8748 221125_WJC_METTL3_EV_vs_WT_F02.18128.18128.2 0.14 20-Aug K.GPAVGIDLGTT.Y "sp|P11142|HSP7C_HUMAN,tr|E9PQQ4|E9PQQ4_HUMAN,tr|E9PNE6|E9PNE6_HUMAN,tr|E9PKE3|E9PKE3_HUMAN,tr|E9PLF4|E9PLF4_HUMAN,tr|E9PI65|E9PI65_HUMAN,tr|E9PK54|E9PK54_HUMAN,tr|E9PN25|E9PN25_HUMAN,tr|E9PPY6|E9PPY6_HUMAN,tr|E9PQK7|E9PQK7_HUMAN" 10 999.5237 - 17451 18128 2 999.523715 500.7691 Heat shock cognate 71 kDa protein OS=Homo sapiens OX=9606 GN=HSPA8 PE=1 SV=1 3.8 3276.6 - 1.37E+06 - - - 0.039 - 1.462 0.215 - 168.7 1 1 0 0 11 0 0 0 - - - - - 1.6564 0.9999 221125_WJC_METTL3_EV_vs_WT_F02.18129.18129.2 8.08E-06 22-Dec K.AAVFEEIDTYER[166.11].R "sp|Q96F86|EDC3_HUMAN,tr|H3BPW9|H3BPW9_HUMAN,tr|H3BSQ0|H3BSQ0_HUMAN" 3 1451.6808 1.16 17452 18129 2 1451.679735 726.8477 Enhancer of mRNA-decapping protein 3 OS=Homo sapiens OX=9606 GN=EDC3 PE=1 SV=1 4 3276.7 - 1.20E+06 - - - -0.7302 - 2.276 0.508 - 640.2 1 2 0 -0.0011 12 0 0 0 1.20E+07 1.03E+07 - - - 4.9567 1 221125_WJC_METTL3_EV_vs_WT_F02.18130.18130.2 7.84E-07 15/26 R.ILATNSELVGTLTR.S "sp|O00268|TAF4_HUMAN,tr|V9GY14|V9GY14_HUMAN,tr|A0A0G2JRY5|A0A0G2JRY5_HUMAN" 3 1486.8355 1.69 17453 18130 2 1486.834299 744.425 Transcription initiation factor TFIID subunit 4 OS=Homo sapiens OX=9606 GN=TAF4 PE=1 SV=2 6 3276.8 - 1.14E+06 - - - -0.8131 - 3.059 0.613 - 874.8 1 2 0 -0.0012 14 0 0 0 8.59E+07 5.07E+07 - - - 6.374 0.9996 221125_WJC_METTL3_EV_vs_WT_F02.18131.18131.2 6.52E-07 13/24 K.FGNEVIPVTVTVK.G "sp|P24752|THIL_HUMAN,tr|A0A5F9ZHJ7|A0A5F9ZHJ7_HUMAN,tr|A0A5F9ZHD4|A0A5F9ZHD4_HUMAN,tr|A0A5F9ZHJ0|A0A5F9ZHJ0_HUMAN,tr|A0A5F9ZHL1|A0A5F9ZHL1_HUMAN,tr|A0A5F9ZI66|A0A5F9ZI66_HUMAN" 6 1401.7868 1.31 17454 18131 2 1401.788102 701.9007 "Acetyl-CoA acetyltransferase, mitochondrial OS=Homo sapiens OX=9606 GN=ACAT1 PE=1 SV=1" 6 3276.9 - 1.13E+06 - - - 0.9524 - 2.321 0.326 - 477.2 1 2 0 0.0013 13 0 0 0 6.56E+08 4.99E+08 - - - 3.6094 0.9999 221125_WJC_METTL3_EV_vs_WT_F02.18134.18134.2 9.46E-07 13/24 R.FVESVDEYQFVER.L "sp|Q13405|RM49_HUMAN,tr|E9PNF1|E9PNF1_HUMAN,tr|E9PI78|E9PI78_HUMAN" 3 1645.7624 1.63 17457 18134 2 1645.761116 823.8885 "39S ribosomal protein L49, mitochondrial OS=Homo sapiens OX=9606 GN=MRPL49 PE=1 SV=1" 4 3277.3 - 826984 - - - -0.7814 - 2.781 0.511 - 461.2 1 2 0 -0.0013 13 0 0 0 1.58E+07 9.69E+06 - - - 5.4399 0.9926 221125_WJC_METTL3_EV_vs_WT_F02.18135.18135.2 1.18 16-Aug R.IQQILNYIK.G "sp|Q9BY41|HDAC8_HUMAN,tr|A0A3B3IT04|A0A3B3IT04_HUMAN,tr|A0A3B3IS68|A0A3B3IS68_HUMAN,tr|A0A3B3IRI9|A0A3B3IRI9_HUMAN,tr|A0A3B3IRV1|A0A3B3IRV1_HUMAN,tr|A0A3B3IT30|A0A3B3IT30_HUMAN,tr|A0A3B3IRJ3|A0A3B3IRJ3_HUMAN,tr|A0A3B3IS37|A0A3B3IS37_HUMAN,tr|A0A3B3IRZ0|A0A3B3IRZ0_HUMAN,tr|A0A3B3ITZ3|A0A3B3ITZ3_HUMAN,tr|A6NFW1|A6NFW1_HUMAN,tr|A0A3B3ISJ4|A0A3B3ISJ4_HUMAN,tr|A0A3B3IU52|A0A3B3IU52_HUMAN,tr|A6NGJ7|A6NGJ7_HUMAN" 14 1131.6652 0.84 17458 18135 2 1131.66605 566.8399 Histone deacetylase 8 OS=Homo sapiens OX=9606 GN=HDAC8 PE=1 SV=2 8.59 3277.4 - 804537 - - - 0.7555 - 1.55 0.086 - 123.7 1 2 0 0.0009 9 0 0 0 9.45E+06 1.12E+07 - - - 0.9438 0.9999 221125_WJC_METTL3_EV_vs_WT_F02.18136.18136.3 3.62E-06 14/44 K.VVLLTEVDK[136.11]LTK[136.11].D sp|P40938|RFC3_HUMAN 1 1372.8512 0.91 17459 18136 3 1372.850032 458.6243 Replication factor C subunit 3 OS=Homo sapiens OX=9606 GN=RFC3 PE=1 SV=2 6.04 3277.5 - 688788 - - - -0.8639 - 2.531 0.485 - 264.8 1 2 1 -0.0012 12 0 0 0 6.04E+06 6.64E+06 - - - 6.5209 0.9999 221125_WJC_METTL3_EV_vs_WT_F02.18137.18137.2 5.08E-07 16/26 R.ILATNSELVGTLTR[166.11].S "sp|O00268|TAF4_HUMAN,tr|V9GY14|V9GY14_HUMAN,tr|A0A0G2JRY5|A0A0G2JRY5_HUMAN" 3 1496.8438 1.69 17460 18137 2 1496.844873 749.4292 Transcription initiation factor TFIID subunit 4 OS=Homo sapiens OX=9606 GN=TAF4 PE=1 SV=2 6 3277.6 - 619867 - - - 0.7315 - 3.381 0.478 - 874 1 2 0 0.0011 14 0 0 0 8.59E+07 5.07E+07 - - - 5.6281 0.9783 221125_WJC_METTL3_EV_vs_WT_F02.18138.18138.3 0.000319 14/48 H.ILEVINAHMVLSK.A "sp|P15927|RFA2_HUMAN,tr|Q5TEJ7|Q5TEJ7_HUMAN,tr|Q5TEJ0|Q5TEJ0_HUMAN" 3 1465.8327 6.58 17461 18138 3 1465.832774 489.6182 Replication protein A 32 kDa subunit OS=Homo sapiens OX=9606 GN=RPA2 PE=1 SV=1 6.75 3277.7 - 542555 - - - 0.0703 - 2.222 0.342 - 134.8 1 1 0 0.0001 13 0 0 0 7.24E+06 1.10E+06 - - - 4.5176 0.8161 221125_WJC_METTL3_EV_vs_WT_F02.18141.18141.2 3.47 12-May R.IGTFDLK.Y "sp|Q14739|LBR_HUMAN,tr|A0A494C1L1|A0A494C1L1_HUMAN" 2 792.4382 18.79 17464 18141 2 792.437859 397.2264 Delta(14)-sterol reductase LBR OS=Homo sapiens OX=9606 GN=LBR PE=1 SV=2 5.84 3278.1 - 299647 - - - -0.3735 - 0.875 0.036 - 62.4 3 2 0 -0.0003 7 0 0 0 5.28E+06 2.81E+05 - - - -1.3294 0.9991 221125_WJC_METTL3_EV_vs_WT_F02.18147.18147.2 0.016 18-Sep R.LETVGSIFSR[166.11].T "sp|Q9Y3D9|RT23_HUMAN,tr|J3QLR8|J3QLR8_HUMAN" 2 1117.6007 1.25 17469 18147 2 1117.603386 559.8076 "28S ribosomal protein S23, mitochondrial OS=Homo sapiens OX=9606 GN=MRPS23 PE=1 SV=2" 6 3278.6 - 9.03E+06 - - - 2.4087 - 1.872 0.374 - 330.9 1 2 0 0.0027 10 0 0 0 1.29E+08 1.04E+08 - - - 3.5527 0.9999 221125_WJC_METTL3_EV_vs_WT_F02.18148.18148.2 1.40E-06 24-Nov K.FGNEVIPVTVTVK[136.11].G "sp|P24752|THIL_HUMAN,tr|A0A5F9ZHJ7|A0A5F9ZHJ7_HUMAN,tr|A0A5F9ZHD4|A0A5F9ZHD4_HUMAN,tr|A0A5F9ZHJ0|A0A5F9ZHJ0_HUMAN,tr|A0A5F9ZHL1|A0A5F9ZHL1_HUMAN,tr|A0A5F9ZI66|A0A5F9ZI66_HUMAN" 6 1409.801 1.31 17470 18148 2 1409.80139 705.9078 "Acetyl-CoA acetyltransferase, mitochondrial OS=Homo sapiens OX=9606 GN=ACAT1 PE=1 SV=1" 6 3278.7 - 7.44E+06 - - - 0.3 - 2.251 0.522 - 270.6 1 2 0 0.0004 13 0 0 0 6.56E+08 5.00E+08 - - - 4.9788 0.9988 221125_WJC_METTL3_EV_vs_WT_F02.18149.18149.2 0.000488 16-Aug R.AQVQLQLFK[136.11].L "sp|Q14683|SMC1A_HUMAN,tr|G8JLG1|G8JLG1_HUMAN" 2 1081.6375 1.05 17471 18149 2 1081.6403 541.826 Structural maintenance of chromosomes protein 1A OS=Homo sapiens OX=9606 GN=SMC1A PE=1 SV=2 8.8 3278.7 - 1.62E+06 - - - 2.5609 - 1.946 0.323 - 267.3 1 2 0 0.0028 9 0 0 0 5.52E+07 5.28E+07 - - - 3.3519 0.9968 221125_WJC_METTL3_EV_vs_WT_F02.18150.18150.2 0.00654 22-Aug K.AAVFEEIDTYER.R "sp|Q96F86|EDC3_HUMAN,tr|H3BPW9|H3BPW9_HUMAN,tr|H3BSQ0|H3BSQ0_HUMAN" 3 1441.6725 0.9 17472 18150 2 1441.675148 721.8435 Enhancer of mRNA-decapping protein 3 OS=Homo sapiens OX=9606 GN=EDC3 PE=1 SV=1 4 3278.8 - 8.91E+06 - - - 1.8194 - 1.343 0.295 - 187 1 2 0 0.0026 12 0 0 0 1.20E+07 1.33E+07 - - - 1.995 0.9993 221125_WJC_METTL3_EV_vs_WT_F02.18152.18152.2 0.107 16-Sep R.AQVQLQLFK.L "sp|Q14683|SMC1A_HUMAN,tr|G8JLG1|G8JLG1_HUMAN" 2 1073.6233 1.01 17474 18152 2 1073.624906 537.8189 Structural maintenance of chromosomes protein 1A OS=Homo sapiens OX=9606 GN=SMC1A PE=1 SV=2 8.8 3278.9 - 1.45E+06 - - - 1.4679 - 2.058 0.279 - 356.6 1 2 0 0.0016 9 0 0 0 5.33E+07 5.28E+07 - - - 3.1892 0.975 221125_WJC_METTL3_EV_vs_WT_F02.18153.18153.2 0.0108 18-Sep K.AFQIMQEELR.Q sp|Q14789|GOGB1_HUMAN 1 1263.6282 19.89 17475 18153 2 1263.631263 632.8214 Golgin subfamily B member 1 OS=Homo sapiens OX=9606 GN=GOLGB1 PE=1 SV=2 4.53 3279 - 1.40E+06 - - - 2.4572 - 1.677 0.038 - 349.3 1 2 0 0.0031 10 0 0 0 1.99E+07 9.99E+05 - - - 0.7638 0.9999 221125_WJC_METTL3_EV_vs_WT_F02.18154.18154.2 9.34E-08 18-Oct K.GC[160.03]C[160.03]FVTFYTR.K "sp|Q92879|CELF1_HUMAN,sp|O95319|CELF2_HUMAN,tr|F5H4Y5|F5H4Y5_HUMAN,tr|G5EA30|G5EA30_HUMAN,tr|E9PSH0|E9PSH0_HUMAN,tr|E9PC62|E9PC62_HUMAN,tr|E9PQK4|E9PQK4_HUMAN,tr|A0A1B0GU44|A0A1B0GU44_HUMAN,tr|E9PKU1|E9PKU1_HUMAN,tr|A0A0J9YX66|A0A0J9YX66_HUMAN,tr|A0A1B0GUN8|A0A1B0GUN8_HUMAN,tr|Q5VZZ6|Q5VZZ6_HUMAN,tr|A0A0J9YXJ0|A0A0J9YXJ0_HUMAN,tr|V9GYD9|V9GYD9_HUMAN,tr|F5H0D8|F5H0D8_HUMAN" 15 1309.5584 0.84 17476 18154 2 1309.558432 655.7865 CUGBP Elav-like family member 1 OS=Homo sapiens OX=9606 GN=CELF1 PE=1 SV=2 8.06 3279.1 - 1.12E+06 - - - 0.0519 - 2.178 0.454 - 586.3 1 2 0 0.0001 10 0 0 0 2.59E+07 3.09E+07 - - - 4.567 0.976 221125_WJC_METTL3_EV_vs_WT_F02.18160.18160.2 4.92 14-Jul K.ELEDLIPK[136.11].N "sp|Q8IWZ3|ANKH1_HUMAN,tr|A0A0A0MQZ8|A0A0A0MQZ8_HUMAN,tr|H0Y472|H0Y472_HUMAN,tr|H0Y7Y3|H0Y7Y3_HUMAN,tr|H0Y4P6|H0Y4P6_HUMAN,tr|H0Y785|H0Y785_HUMAN" 6 963.5368 1.69 17482 18160 2 963.538161 482.7757 Ankyrin repeat and KH domain-containing protein 1 OS=Homo sapiens OX=9606 GN=ANKHD1 PE=1 SV=1 4.14 3279.8 - 479499 - - - 1.399 - 1.115 0.133 - 145.2 1 2 0 0.0013 8 0 0 0 5.22E+07 3.10E+07 - - - 0.3512 0.9996 221125_WJC_METTL3_EV_vs_WT_F02.18161.18161.3 0.00582 Sep-40 R.GLSTESILIPR.Q "sp|P31025|LCN1_HUMAN,sp|Q5VSP4|LC1L1_HUMAN" 2 1184.6765 9.65 17483 18161 3 1184.677585 395.8994 Lipocalin-1 OS=Homo sapiens OX=9606 GN=LCN1 PE=1 SV=1 6 3279.9 - 295212 - - - 0.926 - 1.972 0.323 - 97.7 1 2 0 0.0011 11 0 0 0 6.58E+06 6.82E+05 - - - 4.0699 0.9998 221125_WJC_METTL3_EV_vs_WT_F02.18164.18164.2 1.42E-05 20-Oct R.VVNVSSIMSVR.A sp|P16152|CBR1_HUMAN 1 1189.6489 0.66 17484 18164 2 1189.646887 595.8317 Carbonyl reductase [NADPH] 1 OS=Homo sapiens OX=9606 GN=CBR1 PE=1 SV=3 9.72 3280.3 - 3.94E+06 - - - -1.6862 - 2.135 0.503 - 411.9 1 2 0 -0.002 11 0 0 0 9.95E+07 1.51E+08 - - - 4.8074 0.9997 221125_WJC_METTL3_EV_vs_WT_F02.18167.18167.2 0.00167 14-Aug R.GQAFVIFK[136.11].E "sp|P08579|RU2B_HUMAN,sp|P09012|SNRPA_HUMAN,tr|M0QZG7|M0QZG7_HUMAN,tr|M0R2B8|M0R2B8_HUMAN,tr|M0R0G9|M0R0G9_HUMAN,tr|M0R221|M0R221_HUMAN,tr|M0QXK2|M0QXK2_HUMAN,tr|M0R268|M0R268_HUMAN" 8 916.5262 1.24 17487 18167 2 916.526036 459.2704 U2 small nuclear ribonucleoprotein B'' OS=Homo sapiens OX=9606 GN=SNRPB2 PE=1 SV=1 8.75 3280.5 - 2.34E+06 - - - -0.1669 - 1.776 0.396 - 399.4 1 2 0 -0.0002 8 0 0 0 7.93E+07 6.37E+07 - - - 3.6981 0.9998 221125_WJC_METTL3_EV_vs_WT_F02.18168.18168.2 8.29E-05 18-Sep K.GC[160.03]C[160.03]FVTFYTR[166.11].K "sp|Q92879|CELF1_HUMAN,sp|O95319|CELF2_HUMAN,tr|F5H4Y5|F5H4Y5_HUMAN,tr|G5EA30|G5EA30_HUMAN,tr|E9PSH0|E9PSH0_HUMAN,tr|E9PC62|E9PC62_HUMAN,tr|E9PQK4|E9PQK4_HUMAN,tr|A0A1B0GU44|A0A1B0GU44_HUMAN,tr|E9PKU1|E9PKU1_HUMAN,tr|A0A0J9YX66|A0A0J9YX66_HUMAN,tr|A0A1B0GUN8|A0A1B0GUN8_HUMAN,tr|Q5VZZ6|Q5VZZ6_HUMAN,tr|A0A0J9YXJ0|A0A0J9YXJ0_HUMAN,tr|V9GYD9|V9GYD9_HUMAN,tr|F5H0D8|F5H0D8_HUMAN" 15 1319.5666 0.84 17488 18168 2 1319.566366 660.7906 CUGBP Elav-like family member 1 OS=Homo sapiens OX=9606 GN=CELF1 PE=1 SV=2 8.06 3280.6 - 2.06E+06 - - - -0.2031 - 1.669 0.523 - 368.5 1 2 0 -0.0003 10 0 0 0 2.59E+07 3.09E+07 - - - 4.3336 0.9998 221125_WJC_METTL3_EV_vs_WT_F02.18169.18169.2 0.00248 14-Sep R.SSFDLLPR[166.11].E sp|O94864|ST65G_HUMAN 1 943.5003 1.17 17489 18169 2 943.500185 472.7574 STAGA complex 65 subunit gamma OS=Homo sapiens OX=9606 GN=SUPT7L PE=1 SV=1 5.55 3280.7 - 1.77E+06 - - - -0.071 - 1.999 0.397 - 318.1 1 2 0 -0.0001 8 0 0 0 2.13E+07 1.82E+07 - - - 4.0622 1 221125_WJC_METTL3_EV_vs_WT_F02.18170.18170.3 1.41E-06 14/52 R.ILATNSELVGTLTR.S "sp|O00268|TAF4_HUMAN,tr|V9GY14|V9GY14_HUMAN,tr|A0A0G2JRY5|A0A0G2JRY5_HUMAN" 3 1486.8355 1.37 17490 18170 3 1486.836489 496.6191 Transcription initiation factor TFIID subunit 4 OS=Homo sapiens OX=9606 GN=TAF4 PE=1 SV=2 6 3280.8 - 1.63E+06 - - - 0.6598 - 2.533 0.461 - 238.3 1 2 0 0.001 14 0 0 0 1.45E+07 1.06E+07 - - - 6.1493 0.9997 221125_WJC_METTL3_EV_vs_WT_F02.18171.18171.2 0.00023 18-Oct R.GTPLISPLIK[136.11].W "sp|P49327|FAS_HUMAN,tr|A0A0U1RQF0|A0A0U1RQF0_HUMAN" 2 1045.6627 0.53 17491 18171 2 1045.663245 523.8386 Fatty acid synthase OS=Homo sapiens OX=9606 GN=FASN PE=1 SV=3 8.75 3280.9 - 1.49E+06 - - - 0.5384 - 1.778 0.435 - 214 1 2 0 0.0006 10 0 0 0 9.97E+06 1.89E+07 - - - 3.8601 0.9976 221125_WJC_METTL3_EV_vs_WT_F02.18172.18172.2 0.148 16-Dec R.NLELLSVAR.K sp|Q9H0U6|RM18_HUMAN 1 1013.5869 69.06 17492 18172 2 1013.588325 507.8007 "39S ribosomal protein L18, mitochondrial OS=Homo sapiens OX=9606 GN=MRPL18 PE=1 SV=1" 6 3281 - 1.29E+06 - - - 1.3615 - 1.971 0.138 - 491.4 1 2 0 0.0014 9 0 0 0 6.12E+08 8.86E+06 - - - 2.0229 0.9971 221125_WJC_METTL3_EV_vs_WT_F02.18173.18173.2 0.000187 14/22 R.AVLLVGLC[160.03]DSGK[136.11].T "sp|Q9Y5M8|SRPRB_HUMAN,tr|C9J5Z8|C9J5Z8_HUMAN" 2 1238.6784 1.67 17493 18173 2 1238.684838 620.3465 Signal recognition particle receptor subunit beta OS=Homo sapiens OX=9606 GN=SRPRB PE=1 SV=3 5.87 3281.1 - 1.16E+06 - - - 5.1902 - 2.732 0.414 - 695.3 1 2 0 0.0064 12 0 0 0 1.90E+07 1.14E+07 - - - 4.7412 0.9933 221125_WJC_METTL3_EV_vs_WT_F02.18174.18174.2 3.78E-05 24-Dec L.LGEEEFSYGYSLK.G "sp|Q00839|HNRPU_HUMAN,tr|A0A1W2PQL0|A0A1W2PQL0_HUMAN,tr|A0A1W2PQ74|A0A1W2PQ74_HUMAN,tr|Q5RI18|Q5RI18_HUMAN,tr|A0A1W2PP35|A0A1W2PP35_HUMAN,tr|A0A1W2PPS1|A0A1W2PPS1_HUMAN,tr|A0A1W2PRZ7|A0A1W2PRZ7_HUMAN,tr|A0A1W2PPH7|A0A1W2PPH7_HUMAN,tr|A0A1W2PP34|A0A1W2PP34_HUMAN,tr|A0A1X7SBS1|A0A1X7SBS1_HUMAN" 10 1520.7035 0.99 17494 18174 2 1520.704631 761.359 Heterogeneous nuclear ribonucleoprotein U OS=Homo sapiens OX=9606 GN=HNRNPU PE=1 SV=6 4.25 3281.2 - 1.10E+06 - - - 0.7497 - 3.037 0.468 - 691.4 1 1 0 0.0011 13 0 0 0 1.79E+07 1.80E+07 - - - 5.3484 0.9996 221125_WJC_METTL3_EV_vs_WT_F02.18176.18176.2 6.40E-05 16-Nov K.AAWEAYLSR.L sp|P11172|UMPS_HUMAN 1 1065.5243 0.47 17496 18176 2 1065.525737 533.7694 Uridine 5'-monophosphate synthase OS=Homo sapiens OX=9606 GN=UMPS PE=1 SV=1 6.05 3281.4 - 1.05E+06 - - - 1.3073 - 1.979 0.371 - 440 1 2 0 0.0014 9 0 0 0 1.94E+07 4.11E+07 - - - 3.7555 1 221125_WJC_METTL3_EV_vs_WT_F02.18177.18177.3 2.56E-07 16/40 R.DLFHGATFVPR[166.11].V sp|Q96DV4|RM38_HUMAN 1 1268.6541 1.05 17497 18177 3 1268.653679 423.892 "39S ribosomal protein L38, mitochondrial OS=Homo sapiens OX=9606 GN=MRPL38 PE=1 SV=2" 6.74 3281.5 - 1.01E+06 - - - -0.3523 - 2.824 0.52 - 308.7 1 2 0 -0.0004 11 0 0 0 1.11E+07 1.06E+07 - - - 7.2866 0.9895 221125_WJC_METTL3_EV_vs_WT_F02.18180.18180.2 7.08E-06 13/32 H.VVPTEPLPAPGPASVTE.- "sp|Q9BQA1|MEP50_HUMAN,tr|H0Y711|H0Y711_HUMAN" 2 1659.872 - 17500 18180 2 1659.869752 830.9433 Methylosome protein 50 OS=Homo sapiens OX=9606 GN=WDR77 PE=1 SV=1 4.24 3281.9 - 797326 - - - -1.326 - 1.984 0.55 - 311.6 1 1 0 -0.0022 17 0 0 0 - - - - - 4.787 0.9996 221125_WJC_METTL3_EV_vs_WT_F02.18185.18185.2 0.0261 14-Sep R.VDEIIWVK[136.11].T sp|Q86U44|MTA70_HUMAN 1 1008.5735 0.18 17504 18185 2 1008.573969 505.294 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 4.37 3282.5 - 4.75E+06 - - - 0.4323 - 2.093 0.264 - 270 1 2 0 0.0004 8 0 0 0 3.00E+06 1.70E+07 - - - 3.2183 0.9996 221125_WJC_METTL3_EV_vs_WT_F02.18187.18187.2 0.0119 14-Jul R.GQAFVIFK.E "sp|P08579|RU2B_HUMAN,sp|P09012|SNRPA_HUMAN,tr|M0QZG7|M0QZG7_HUMAN,tr|M0R2B8|M0R2B8_HUMAN,tr|M0R0G9|M0R0G9_HUMAN,tr|M0R221|M0R221_HUMAN,tr|M0QXK2|M0QXK2_HUMAN,tr|M0R268|M0R268_HUMAN" 8 908.512 1.34 17505 18187 2 908.512023 455.2633 U2 small nuclear ribonucleoprotein B'' OS=Homo sapiens OX=9606 GN=SNRPB2 PE=1 SV=1 8.75 3282.7 - 5.08E+06 - - - 0.0374 - 1.656 0.372 - 299.3 1 2 0 0 8 0 0 0 8.60E+07 6.43E+07 - - - 3.3098 1 221125_WJC_METTL3_EV_vs_WT_F02.18188.18188.3 5.18E-05 Oct-40 K.NALESYAFNMK[136.11].S "sp|P0DMV8|HS71A_HUMAN,sp|P34931|HS71L_HUMAN,sp|P0DMV9|HS71B_HUMAN,tr|Q53FA3|Q53FA3_HUMAN,tr|V9GZ37|V9GZ37_HUMAN,tr|A0A0G2JIW1|A0A0G2JIW1_HUMAN" 6 1294.6107 0.13 17506 18188 3 1294.610474 432.5442 Heat shock 70 kDa protein 1A OS=Homo sapiens OX=9606 GN=HSPA1A PE=1 SV=1 6 3282.7 - 4.39E+06 - - - -0.1923 - 2.198 0.533 - 108.1 1 2 0 -0.0002 11 0 0 0 2.97E+07 2.31E+08 - - - 6.7196 0.9999 221125_WJC_METTL3_EV_vs_WT_F02.18189.18189.3 0.000277 Nov-48 K.FGNEVIPVTVTVK[136.11].G "sp|P24752|THIL_HUMAN,tr|A0A5F9ZHJ7|A0A5F9ZHJ7_HUMAN,tr|A0A5F9ZHD4|A0A5F9ZHD4_HUMAN,tr|A0A5F9ZHJ0|A0A5F9ZHJ0_HUMAN,tr|A0A5F9ZHL1|A0A5F9ZHL1_HUMAN,tr|A0A5F9ZI66|A0A5F9ZI66_HUMAN" 6 1409.801 1.21 17507 18189 3 1409.801664 470.9409 "Acetyl-CoA acetyltransferase, mitochondrial OS=Homo sapiens OX=9606 GN=ACAT1 PE=1 SV=1" 6 3282.8 - 2.34E+06 - - - 0.4944 - 2.076 0.453 - 240.5 1 2 0 0.0007 13 0 0 0 2.11E+07 1.74E+07 - - - 5.5708 1 221125_WJC_METTL3_EV_vs_WT_F02.18192.18192.3 1.18E-05 14/40 R.DLFHGATFVPR.V sp|Q96DV4|RM38_HUMAN 1 1258.6459 1.05 17510 18192 3 1258.645926 420.5559 "39S ribosomal protein L38, mitochondrial OS=Homo sapiens OX=9606 GN=MRPL38 PE=1 SV=2" 6.74 3283 - 1.60E+06 - - - 0.0556 - 2.534 0.541 - 205.9 1 2 0 0.0001 11 0 0 0 1.11E+07 1.06E+07 - - - 7.213 0.9996 221125_WJC_METTL3_EV_vs_WT_F02.18195.18195.2 0.000144 20-Nov R.LAETVFNFQEK[136.11].V "sp|Q14204|DYHC1_HUMAN,tr|A0A7P0T8N2|A0A7P0T8N2_HUMAN,tr|A0A7P0T9C4|A0A7P0T9C4_HUMAN,tr|A0A7P0TBJ7|A0A7P0TBJ7_HUMAN,tr|A0A804HHY6|A0A804HHY6_HUMAN,tr|A0A7P0T9K2|A0A7P0T9K2_HUMAN,tr|A0A7P0TB64|A0A7P0TB64_HUMAN,tr|A0A2R8Y706|A0A2R8Y706_HUMAN,tr|A0A7P0T916|A0A7P0T916_HUMAN,tr|A0A7P0TB75|A0A7P0TB75_HUMAN,tr|A0A7P0T8W5|A0A7P0T8W5_HUMAN,tr|A0A7P0T9S3|A0A7P0T9S3_HUMAN,tr|A0A7P0TAF3|A0A7P0TAF3_HUMAN,tr|A0A7P0T9F1|A0A7P0T9F1_HUMAN,tr|A0A7P0TAW9|A0A7P0TAW9_HUMAN,tr|A0A2R8YGC7|A0A2R8YGC7_HUMAN,tr|A0A7P0TA13|A0A7P0TA13_HUMAN,tr|A0A7P0T934|A0A7P0T934_HUMAN,tr|A0A7P0TAV5|A0A7P0TAV5_HUMAN,tr|A0A7P0T9Y3|A0A7P0T9Y3_HUMAN,tr|A0A7P0T7V5|A0A7P0T7V5_HUMAN,tr|A0A7P0T9R4|A0A7P0T9R4_HUMAN,tr|A0A2R8Y5T0|A0A2R8Y5T0_HUMAN,tr|A0A7P0T990|A0A7P0T990_HUMAN,tr|A0A7P0T942|A0A7P0T942_HUMAN,tr|A0A2R8YFZ7|A0A2R8YFZ7_HUMAN,tr|A0A7P0T825|A0A7P0T825_HUMAN,tr|A0A2R8Y6H2|A0A2R8Y6H2_HUMAN,tr|A0A7P0TBC9|A0A7P0TBC9_HUMAN,tr|A0A7P0TAM4|A0A7P0TAM4_HUMAN" 30 1332.6805 0.74 17513 18195 2 1332.683649 667.3475 Cytoplasmic dynein 1 heavy chain 1 OS=Homo sapiens OX=9606 GN=DYNC1H1 PE=1 SV=5 4.53 3283.4 - 1.06E+06 - - - 2.3502 - 2.415 0.412 - 476.3 1 2 0 0.0031 11 0 0 0 1.43E+07 1.94E+07 - - - 4.4683 0.9999 221125_WJC_METTL3_EV_vs_WT_F02.18197.18197.3 5.39E-05 13/40 K.NALESYAFNMK.S "sp|P0DMV8|HS71A_HUMAN,sp|P34931|HS71L_HUMAN,sp|P0DMV9|HS71B_HUMAN,tr|Q53FA3|Q53FA3_HUMAN,tr|V9GZ37|V9GZ37_HUMAN,tr|A0A0G2JIW1|A0A0G2JIW1_HUMAN" 6 1286.5965 0.13 17515 18197 3 1286.598319 429.8728 Heat shock 70 kDa protein 1A OS=Homo sapiens OX=9606 GN=HSPA1A PE=1 SV=1 6 3283.7 - 568282 - - - 1.3959 - 2.151 0.441 - 197.8 1 2 0 0.0018 11 0 0 0 2.97E+07 2.31E+08 - - - 5.6321 0.9998 221125_WJC_METTL3_EV_vs_WT_F02.18202.18202.2 0.000955 14-Sep R.WSLEALNR.D "sp|Q5HYI8|RABL3_HUMAN,tr|F8WF50|F8WF50_HUMAN,tr|C9JXM3|C9JXM3_HUMAN,tr|F8WDC7|F8WDC7_HUMAN" 4 987.5138 0.49 17518 18202 2 987.512865 494.7642 Rab-like protein 3 OS=Homo sapiens OX=9606 GN=RABL3 PE=1 SV=1 6 3284.3 - 1.59E+06 - - - -0.9266 - 1.878 0.443 - 381.5 1 2 0 -0.0009 8 0 0 0 1.76E+07 3.57E+07 - - - 4.2134 0.9998 221125_WJC_METTL3_EV_vs_WT_F02.18203.18203.2 0.1 20-Nov K.NTLLIAGLQAR.N "sp|P39656|OST48_HUMAN,tr|A0A0C4DGS1|A0A0C4DGS1_HUMAN" 2 1168.6928 1.38 17519 18203 2 1168.693166 585.3537 Dolichyl-diphosphooligosaccharide--protein glycosyltransferase 48 kDa subunit OS=Homo sapiens OX=9606 GN=DDOST PE=1 SV=4 9.75 3284.3 - 2.86E+06 - - - 0.3072 - 2.15 0.377 - 357.7 1 2 0 0.0004 11 0 0 0 1.63E+08 1.18E+08 - - - 3.8962 0.9784 221125_WJC_METTL3_EV_vs_WT_F02.18204.18204.2 0.653 20-Jul K.TVVLPPIVASR[166.11].G "sp|O75152|ZC11A_HUMAN,tr|E9PBY7|E9PBY7_HUMAN,tr|E9PQ61|E9PQ61_HUMAN" 3 1160.7157 1.04 17520 18204 2 1160.715788 581.3651 Zinc finger CCCH domain-containing protein 11A OS=Homo sapiens OX=9606 GN=ZC3H11A PE=1 SV=3 9.41 3284.4 - 2.40E+06 - - - 0.1068 - 1.299 0.049 - 113.2 1 2 0 0.0001 11 0 0 0 2.77E+07 2.67E+07 - - - 0.1106 0.9991 221125_WJC_METTL3_EV_vs_WT_F02.18205.18205.2 0.149 20-Nov K.TVVLPPIVASR.G "sp|O75152|ZC11A_HUMAN,tr|E9PBY7|E9PBY7_HUMAN,tr|E9PQ61|E9PQ61_HUMAN" 3 1150.7074 1.04 17521 18205 2 1150.709662 576.361 Zinc finger CCCH domain-containing protein 11A OS=Homo sapiens OX=9606 GN=ZC3H11A PE=1 SV=3 9.41 3284.5 - 2.04E+06 - - - 1.971 - 2.087 0.297 - 415.9 1 2 0 0.0023 11 0 0 0 2.77E+07 2.67E+07 - - - 3.2242 1 221125_WJC_METTL3_EV_vs_WT_F02.18207.18207.3 0.000375 18/52 K.LGASPLHVDLATLR[166.11].E "sp|Q15904|VAS1_HUMAN,tr|A0A7I2V3T8|A0A7I2V3T8_HUMAN,tr|A0A7I2YQA5|A0A7I2YQA5_HUMAN,tr|A6QRJ1|A6QRJ1_HUMAN" 4 1471.8386 2.22 17523 18207 3 1471.838237 491.6202 V-type proton ATPase subunit S1 OS=Homo sapiens OX=9606 GN=ATP6AP1 PE=1 SV=2 6.74 3284.7 - 1.36E+06 - - - -0.2691 - 2.848 0.431 - 428 1 2 0 -0.0004 14 0 0 0 1.83E+07 8.24E+06 - - - 6.1265 0.9991 221125_WJC_METTL3_EV_vs_WT_F02.18208.18208.2 0.018 16-Aug K.WMPFTNPAR[166.11].K "sp|Q9NPF5|DMAP1_HUMAN,tr|Q5TG39|Q5TG39_HUMAN,tr|Q5TG38|Q5TG38_HUMAN,tr|Q5TG40|Q5TG40_HUMAN,tr|Q5TG36|Q5TG36_HUMAN,tr|Q5TG37|Q5TG37_HUMAN" 6 1128.5414 1.31 17524 18208 2 1128.540634 565.278 DNA methyltransferase 1-associated protein 1 OS=Homo sapiens OX=9606 GN=DMAP1 PE=1 SV=1 9.75 3284.8 - 996414 - - - -0.6832 - 1.475 0.313 - 161.3 1 2 0 -0.0008 9 0 0 0 1.61E+07 1.23E+07 - - - 2.477 0.9988 221125_WJC_METTL3_EV_vs_WT_F02.18210.18210.2 0.00396 14/26 K.ALGLSTDDAYEELR[166.11].Q "sp|Q9UK61|TASOR_HUMAN,tr|A0A087X0F1|A0A087X0F1_HUMAN" 2 1561.7499 1.28 17526 18210 2 1561.747388 781.8822 Protein TASOR OS=Homo sapiens OX=9606 GN=TASOR PE=1 SV=3 3.92 3285.1 - 532872 - - - -1.6321 - 2.09 0.238 - 426.7 1 2 0 -0.0025 14 0 0 0 1.00E+07 7.84E+06 - - - 2.6479 1 221125_WJC_METTL3_EV_vs_WT_F02.18211.18211.2 1.98E-09 14/24 K.IEWDYEC[160.03]EPGMVK.G "sp|Q8NBT2|SPC24_HUMAN,tr|K7EJH0|K7EJH0_HUMAN,tr|K7EMX1|K7EMX1_HUMAN" 3 1654.7007 27.64 17527 18211 2 1654.697059 828.3576 Kinetochore protein Spc24 OS=Homo sapiens OX=9606 GN=SPC24 PE=1 SV=2 4 3285.2 - 518716 - - - -2.2185 - 2.431 0.677 - 613.2 1 2 0 -0.0037 13 0 0 0 7.10E+06 2.57E+05 - - - 6.32 0.9944 221125_WJC_METTL3_EV_vs_WT_F02.18213.18213.2 0.0279 16-Oct R.NIEEILTAR.G sp|Q5SXM8|DNLZ_HUMAN 1 1057.5768 13.48 17528 18213 2 1057.576562 529.7957 DNL-type zinc finger protein OS=Homo sapiens OX=9606 GN=DNLZ PE=1 SV=1 4.53 3285.5 - 1.56E+06 - - - -0.2005 - 1.753 0.048 - 253 1 2 0 -0.0002 9 0 0 0 1.13E+08 8.35E+06 - - - 1.0194 0.9791 221125_WJC_METTL3_EV_vs_WT_F02.18215.18215.2 0.128 12-Jun K.EFEWNLK[136.11].S sp|Q9BYJ9|YTHD1_HUMAN 1 972.4796 1.46 17529 18215 2 972.478614 487.2471 YTH domain-containing family protein 1 OS=Homo sapiens OX=9606 GN=YTHDF1 PE=1 SV=1 4.53 3285.7 - 6.31E+06 - - - -1.0468 - 1.097 0.125 - 169.8 1 2 0 -0.001 7 0 0 0 1.00E+08 6.84E+07 - - - 0.2573 0.9994 221125_WJC_METTL3_EV_vs_WT_F02.18217.18217.2 0.343 20-Oct K.NTLLIAGLQAR[166.11].N "sp|P39656|OST48_HUMAN,tr|A0A0C4DGS1|A0A0C4DGS1_HUMAN" 2 1178.7011 1.38 17531 18217 2 1178.701939 590.3578 Dolichyl-diphosphooligosaccharide--protein glycosyltransferase 48 kDa subunit OS=Homo sapiens OX=9606 GN=DDOST PE=1 SV=4 9.75 3285.8 - 6.39E+06 - - - 0.7313 - 2.327 0.229 - 292.5 1 2 0 0.0009 11 0 0 0 1.63E+08 1.18E+08 - - - 3.0169 0.9994 221125_WJC_METTL3_EV_vs_WT_F02.18218.18218.2 0.00109 20-Aug K.LISSVDPQFLK[136.11].L "sp|Q9BVG4|PBDC1_HUMAN,tr|A6NDF3|A6NDF3_HUMAN" 2 1253.7111 0.13 17532 18218 2 1253.709311 627.8628 Protein PBDC1 OS=Homo sapiens OX=9606 GN=PBDC1 PE=1 SV=1 5.84 3285.9 - 2.27E+06 - - - -1.4182 - 1.663 0.392 - 134.5 1 2 0 -0.0018 11 0 0 0 4.42E+06 3.50E+07 - - - 3.3117 1 221125_WJC_METTL3_EV_vs_WT_F02.18219.18219.2 0.000307 18/26 R.PSAAGINLMIGSTR.Y sp|Q08211|DHX9_HUMAN 1 1386.7289 1.21 17533 18219 2 1386.729182 694.3717 ATP-dependent RNA helicase A OS=Homo sapiens OX=9606 GN=DHX9 PE=1 SV=4 10.18 3286 - 1.75E+06 - - - 0.1788 - 3.645 0.563 - 1341.8 1 1 0 0.0002 14 0 0 0 7.62E+07 6.31E+07 - - - 6.4449 1 221125_WJC_METTL3_EV_vs_WT_F02.18221.18221.2 1.11E-08 20/30 K.YVVVTGITPTPLGEGK.S "sp|P11586|C1TC_HUMAN,tr|F5H2F4|F5H2F4_HUMAN,tr|V9GZ78|V9GZ78_HUMAN,tr|V9GYY3|V9GYY3_HUMAN,tr|A0A494C1T2|A0A494C1T2_HUMAN" 5 1629.8978 1.76 17535 18221 2 1629.901272 815.9562 "C-1-tetrahydrofolate synthase, cytoplasmic OS=Homo sapiens OX=9606 GN=MTHFD1 PE=1 SV=4" 6 3286.3 - 1.53E+06 - - - 2.1461 - 3.163 0.611 - 1182.7 1 2 0 0.0035 16 0 0 0 2.60E+08 1.48E+08 - - - 6.3838 1 221125_WJC_METTL3_EV_vs_WT_F02.18222.18222.2 7.87E-07 14/26 K.ALGLSTDDAYEELR.Q "sp|Q9UK61|TASOR_HUMAN,tr|A0A087X0F1|A0A087X0F1_HUMAN" 2 1551.7417 1.28 17536 18222 2 1551.742243 776.8781 Protein TASOR OS=Homo sapiens OX=9606 GN=TASOR PE=1 SV=3 3.92 3286.4 - 1.35E+06 - - - 0.3712 - 2.921 0.583 - 738.1 1 2 0 0.0006 14 0 0 0 1.00E+07 7.84E+06 - - - 6.0368 0.9996 221125_WJC_METTL3_EV_vs_WT_F02.18224.18224.2 0.000195 16-Sep R.DFFLANASR[166.11].A sp|P07384|CAN1_HUMAN 1 1049.517 1.7 17538 18224 2 1049.516109 525.7658 Calpain-1 catalytic subunit OS=Homo sapiens OX=9606 GN=CAPN1 PE=1 SV=1 5.84 3286.7 - 1.13E+06 - - - -0.8147 - 1.711 0.39 - 295.2 1 2 0 -0.0009 9 0 0 0 1.74E+07 1.03E+07 - - - 3.4751 0.9998 221125_WJC_METTL3_EV_vs_WT_F02.18227.18227.2 2.67E-07 22-Dec R.FGEVSDVEIITR[166.11].K "sp|Q76FK4|NOL8_HUMAN,tr|F5GWN9|F5GWN9_HUMAN,tr|F5H101|F5H101_HUMAN,tr|F5GXV1|F5GXV1_HUMAN,tr|F5H0I5|F5H0I5_HUMAN,tr|F5H8B8|F5H8B8_HUMAN,tr|A0A0A0MSJ1|A0A0A0MSJ1_HUMAN,tr|F5H532|F5H532_HUMAN,tr|F8WE42|F8WE42_HUMAN" 9 1373.7066 1.53 17541 18227 2 1373.708425 687.8606 Nucleolar protein 8 OS=Homo sapiens OX=9606 GN=NOL8 PE=1 SV=1 4.14 3287 - 931427 - - - 1.3169 - 2.579 0.498 - 576.4 1 2 0 0.0018 12 0 0 0 1.32E+07 8.62E+06 - - - 5.2114 0.9999 221125_WJC_METTL3_EV_vs_WT_F02.18229.18229.2 0.000209 30-Oct K.TITLEVEPSDTIENVK[136.11].A "sp|P62979|RS27A_HUMAN,sp|P0CG48|UBC_HUMAN,sp|P0CG47|UBB_HUMAN,sp|P62987|RL40_HUMAN,tr|F5H388|F5H388_HUMAN,tr|F5GYU3|F5GYU3_HUMAN,tr|B4DV12|B4DV12_HUMAN,tr|J3QSA3|J3QSA3_HUMAN,tr|Q5PY61|Q5PY61_HUMAN,tr|F5H2Z3|F5H2Z3_HUMAN,tr|J3QS39|J3QS39_HUMAN,tr|J3QTR3|J3QTR3_HUMAN,tr|Q96C32|Q96C32_HUMAN,tr|M0R1V7|M0R1V7_HUMAN,tr|F5H747|F5H747_HUMAN,tr|F5H747|F5H747_HUMAN,tr|F5GXK7|F5GXK7_HUMAN,tr|F5GXK7|F5GXK7_HUMAN,tr|F5H6Q2|F5H6Q2_HUMAN,tr|F5GZ39|F5GZ39_HUMAN,tr|J3QKN0|J3QKN0_HUMAN,tr|J3QKN0|J3QKN0_HUMAN,tr|J3QKN0|J3QKN0_HUMAN,tr|F5H265|F5H265_HUMAN" 24 1794.9342 -1 17543 18229 2 1794.934375 898.4744 Ubiquitin-40S ribosomal protein S27a OS=Homo sapiens OX=9606 GN=RPS27A PE=1 SV=2 4 3287.3 - 334218 - - - 0.0836 - 2.045 0.538 - 178.4 1 2 0 0.0001 16 0 0 0 0.00E+00 0.00E+00 - - - 4.7735 0.9998 221125_WJC_METTL3_EV_vs_WT_F02.18231.18231.2 0.000165 18-Oct K.FAAQELIEVK[136.11].R "sp|Q86U44|MTA70_HUMAN,tr|F5H6D8|F5H6D8_HUMAN,tr|H0YFV6|H0YFV6_HUMAN,tr|B4DTN4|B4DTN4_HUMAN" 4 1154.6427 0.02 17544 18231 2 1154.642507 578.3286 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 4.53 3287.5 - 5.82E+07 - - - -0.1455 - 1.983 0.435 - 249.7 1 2 0 -0.0002 10 0 0 0 2.31E+07 9.84E+08 - - - 4.1648 0.9998 221125_WJC_METTL3_EV_vs_WT_F02.18234.18234.2 0.00412 18-Oct K.LLLDDSFETK[136.11].K "sp|O00443|P3C2A_HUMAN,tr|A0A0C4DGF9|A0A0C4DGF9_HUMAN,tr|E9PPP3|E9PPP3_HUMAN" 3 1187.6165 1.41 17546 18234 2 1187.6172 594.8155 Phosphatidylinositol 4-phosphate 3-kinase C2 domain-containing subunit alpha OS=Homo sapiens OX=9606 GN=PIK3C2A PE=1 SV=2 4.03 3287.7 - 5.41E+06 - - - 0.5726 - 1.872 0.431 - 246.6 1 2 0 0.0007 10 0 0 0 1.01E+08 7.17E+07 - - - 3.9743 0.9599 221125_WJC_METTL3_EV_vs_WT_F02.18235.18235.2 0.0186 18-Sep L.TIEDGIFEVK.S "sp|P54652|HSP72_HUMAN,sp|P11142|HSP7C_HUMAN,tr|E9PKE3|E9PKE3_HUMAN,tr|E9PN89|E9PN89_HUMAN" 4 1149.5918 0.15 17547 18235 2 1149.590902 575.8032 Heat shock-related 70 kDa protein 2 OS=Homo sapiens OX=9606 GN=HSPA2 PE=1 SV=1 4.14 3287.8 - 5.53E+06 - - - -0.742 - 1.621 0.324 - 161.2 1 1 0 -0.0009 10 0 0 0 2.98E+08 2.04E+09 - - - 2.7821 1 221125_WJC_METTL3_EV_vs_WT_F02.18236.18236.3 3.08E-06 23/52 R.MALIGLGVSHPVLK.Q "sp|P22695|QCR2_HUMAN,tr|H3BRG4|H3BRG4_HUMAN,tr|H3BSJ9|H3BSJ9_HUMAN" 3 1433.8428 1.4 17548 18236 3 1433.842004 478.9549 "Cytochrome b-c1 complex subunit 2, mitochondrial OS=Homo sapiens OX=9606 GN=UQCRC2 PE=1 SV=3" 8.52 3287.9 - 4.12E+06 - - - -0.5844 - 3.716 0.465 - 849.7 1 2 0 -0.0008 14 0 0 0 9.38E+07 6.68E+07 - - - 7.2125 1 221125_WJC_METTL3_EV_vs_WT_F02.18237.18237.2 7.01E-08 14/30 K.YVVVTGITPTPLGEGK[136.11].S "sp|P11586|C1TC_HUMAN,tr|F5H2F4|F5H2F4_HUMAN,tr|V9GZ78|V9GZ78_HUMAN,tr|V9GYY3|V9GYY3_HUMAN,tr|A0A494C1T2|A0A494C1T2_HUMAN" 5 1637.912 1.76 17549 18237 2 1637.91152 819.9633 "C-1-tetrahydrofolate synthase, cytoplasmic OS=Homo sapiens OX=9606 GN=MTHFD1 PE=1 SV=4" 6 3287.9 - 4.09E+06 - - - -0.2772 - 2.777 0.621 - 535.3 1 2 0 -0.0005 16 0 0 0 2.60E+08 1.48E+08 - - - 6.1387 1 221125_WJC_METTL3_EV_vs_WT_F02.18239.18239.2 1.10E-09 15/28 R.IIDVVYNASNNELVR[166.11].T "sp|P62241|RS8_HUMAN,tr|Q5JR95|Q5JR95_HUMAN" 2 1727.9082 0.95 17551 18239 2 1727.909226 864.9614 40S ribosomal protein S8 OS=Homo sapiens OX=9606 GN=RPS8 PE=1 SV=2 4.37 3288.2 - 2.70E+06 - - - 0.6117 - 3.09 0.627 - 588.6 1 2 0 0.0011 15 0 0 0 9.84E+07 1.03E+08 - - - 6.4454 0.9997 221125_WJC_METTL3_EV_vs_WT_F02.18240.18240.2 0.000215 16-Aug R.DFFLANASR.A sp|P07384|CAN1_HUMAN 1 1039.5087 1.7 17552 18240 2 1039.507959 520.7616 Calpain-1 catalytic subunit OS=Homo sapiens OX=9606 GN=CAPN1 PE=1 SV=1 5.84 3288.2 - 1.97E+06 - - - -0.7071 - 1.514 0.47 - 242.3 1 2 0 -0.0007 9 0 0 0 1.74E+07 1.03E+07 - - - 3.7121 1 221125_WJC_METTL3_EV_vs_WT_F02.18241.18241.2 9.09E-07 15/26 K.VPDSTYEMIGGLDK[136.11].Q "sp|P62195|PRS8_HUMAN,tr|J3QQM1|J3QQM1_HUMAN,tr|J3KRP2|J3KRP2_HUMAN,tr|J3QSA9|J3QSA9_HUMAN,tr|J3QLH6|J3QLH6_HUMAN,tr|J3QSE0|J3QSE0_HUMAN,tr|J3QRW1|J3QRW1_HUMAN" 7 1531.732 0.86 17553 18241 2 1531.727696 766.8733 26S proteasome regulatory subunit 8 OS=Homo sapiens OX=9606 GN=PSMC5 PE=1 SV=1 4.03 3288.3 - 1.87E+06 - - - -2.7838 - 2.724 0.614 - 887.5 1 2 0 -0.0043 14 0 0 0 3.85E+07 4.46E+07 - - - 6.0894 0.999 221125_WJC_METTL3_EV_vs_WT_F02.18242.18242.2 0.000733 16-Nov R.VSEEIFFGR.L sp|Q9Y4W6|AFG32_HUMAN 1 1082.5397 1.4 17554 18242 2 1082.536179 542.2771 AFG3-like protein 2 OS=Homo sapiens OX=9606 GN=AFG3L2 PE=1 SV=2 4.53 3288.4 - 1.68E+06 - - - -3.2156 - 2.169 0.386 - 563.2 1 2 0 -0.0035 9 0 0 0 3.32E+07 2.36E+07 - - - 4.1309 0.9012 221125_WJC_METTL3_EV_vs_WT_F02.18245.18245.2 1.47 16-Jul K.WYIPDPTGK.F sp|Q68CQ7|GL8D1_HUMAN 1 1075.5338 1.12 17557 18245 2 1075.537819 538.7742 Glycosyltransferase 8 domain-containing protein 1 OS=Homo sapiens OX=9606 GN=GLT8D1 PE=1 SV=2 5.83 3288.8 - 1.55E+06 - - - 3.694 - 1.172 0.12 - 115.4 1 2 0 0.004 9 0 0 0 4.98E+07 4.46E+07 - - - 0.3852 1 221125_WJC_METTL3_EV_vs_WT_F02.18246.18246.3 4.14E-07 19/56 K.VIIVDAENVLVADK[136.11]R[166.11].L "sp|Q8NDZ4|DIK2A_HUMAN,tr|E7ET39|E7ET39_HUMAN,tr|C9JY09|C9JY09_HUMAN" 3 1670.9686 1.34 17558 18246 3 1670.969941 557.9968 Divergent protein kinase domain 2A OS=Homo sapiens OX=9606 GN=DIPK2A PE=1 SV=1 4.56 3288.9 - 1.44E+06 - - - 0.8079 - 2.917 0.556 - 436.9 1 2 0 0.0014 15 0 0 0 1.42E+07 1.06E+07 - - - 7.5319 0.995 221125_WJC_METTL3_EV_vs_WT_F02.18250.18250.2 0.204 14-Aug R.DFFPDVEK.L "sp|Q96DF8|ESS2_HUMAN,tr|F8WEF8|F8WEF8_HUMAN" 2 995.46 1.82 17560 18250 2 995.458968 498.7373 Splicing factor ESS-2 homolog OS=Homo sapiens OX=9606 GN=ESS2 PE=1 SV=1 4.03 3289.3 - 3.24E+06 - - - -1.0498 - 1.254 0.207 - 217.5 1 2 0 -0.001 8 0 0 0 1.92E+08 1.06E+08 - - - 1.2522 1 221125_WJC_METTL3_EV_vs_WT_F02.18251.18251.2 2.43E-09 14/28 R.IIDVVYNASNNELVR.T "sp|P62241|RS8_HUMAN,tr|Q5JR95|Q5JR95_HUMAN" 2 1717.8999 0.96 17561 18251 2 1717.899186 859.9572 40S ribosomal protein S8 OS=Homo sapiens OX=9606 GN=RPS8 PE=1 SV=2 4.37 3289.4 - 4.40E+06 - - - -0.415 - 3.078 0.549 - 641.3 1 2 0 -0.0007 15 0 0 0 9.84E+07 1.03E+08 - - - 5.8598 0.9995 221125_WJC_METTL3_EV_vs_WT_F02.18253.18253.2 0.101 16-Oct R.LPELFETGR[166.11].Q sp|P78318|IGBP1_HUMAN 1 1070.5636 0.94 17563 18253 2 1070.563406 536.2891 Immunoglobulin-binding protein 1 OS=Homo sapiens OX=9606 GN=IGBP1 PE=1 SV=1 4.53 3289.6 - 2.05E+06 - - - -0.1625 - 1.84 0.288 - 349.8 1 2 0 -0.0002 9 0 0 0 5.07E+07 5.37E+07 - - - 2.9322 0.9924 221125_WJC_METTL3_EV_vs_WT_F02.18255.18255.2 0.205 16-Jul R.EGLEYIPLR[166.11].H "sp|Q15392|DHC24_HUMAN,tr|A0A0A0MTI1|A0A0A0MTI1_HUMAN" 2 1098.5949 1.4 17565 18255 2 1098.594951 550.3047 Delta(24)-sterol reductase OS=Homo sapiens OX=9606 GN=DHCR24 PE=1 SV=2 4.53 3289.8 - 1.54E+06 - - - 0.0646 - 1.271 0.146 - 141.3 1 2 0 0.0001 9 0 0 0 2.05E+07 1.46E+07 - - - 0.8131 0.9995 221125_WJC_METTL3_EV_vs_WT_F02.18256.18256.2 0.267 20-Aug R.ENVLFLTSGTR[166.11].R "sp|Q14244|MAP7_HUMAN,tr|A0A087WZ40|A0A087WZ40_HUMAN" 2 1245.6593 0.75 17566 18256 2 1245.659596 623.8369 Ensconsin OS=Homo sapiens OX=9606 GN=MAP7 PE=1 SV=1 6.1 3289.9 - 1.05E+06 - - - 0.2609 - 1.994 0.321 - 223.2 2 2 0 0.0003 11 0 0 0 1.54E+07 2.05E+07 - - - 3.1443 0.9995 221125_WJC_METTL3_EV_vs_WT_F02.18258.18258.2 0.00138 14/24 K.IPGGIIEDSC[160.03]VLR[166.11].G "sp|P49368|TCPG_HUMAN,tr|E9PRC8|E9PRC8_HUMAN,tr|B4DUR8|B4DUR8_HUMAN,tr|E9PQ35|E9PQ35_HUMAN,tr|Q5SZX6|Q5SZX6_HUMAN" 5 1437.7525 0.26 17567 18258 2 1437.748444 719.8835 T-complex protein 1 subunit gamma OS=Homo sapiens OX=9606 GN=CCT3 PE=1 SV=4 4.37 3290.1 - 2.51E+06 - - - -2.835 - 2.577 0.44 - 721.6 1 2 0 -0.0041 13 0 0 0 2.87E+07 1.11E+08 - - - 4.7191 1 221125_WJC_METTL3_EV_vs_WT_F02.18261.18261.2 1.02E-09 17/26 K.VPDSTYEMIGGLDK.Q "sp|P62195|PRS8_HUMAN,tr|J3QQM1|J3QQM1_HUMAN,tr|J3KRP2|J3KRP2_HUMAN,tr|J3QSA9|J3QSA9_HUMAN,tr|J3QLH6|J3QLH6_HUMAN,tr|J3QSE0|J3QSE0_HUMAN,tr|J3QRW1|J3QRW1_HUMAN" 7 1523.7178 0.86 17569 18261 2 1523.716703 762.8662 26S proteasome regulatory subunit 8 OS=Homo sapiens OX=9606 GN=PSMC5 PE=1 SV=1 4.03 3290.5 - 1.38E+06 - - - -0.6937 - 2.78 0.613 - 1018.1 1 2 0 -0.0011 14 0 0 0 3.85E+07 4.48E+07 - - - 6.1341 1 221125_WJC_METTL3_EV_vs_WT_F02.18263.18263.3 4.19E-06 17/52 R.MALIGLGVSHPVLK[136.11].Q "sp|P22695|QCR2_HUMAN,tr|H3BRG4|H3BRG4_HUMAN,tr|H3BSJ9|H3BSJ9_HUMAN" 3 1441.857 1.4 17571 18263 3 1441.857616 481.6263 "Cytochrome b-c1 complex subunit 2, mitochondrial OS=Homo sapiens OX=9606 GN=UQCRC2 PE=1 SV=3" 8.52 3290.6 - 4.32E+06 - - - 0.3981 - 3.112 0.443 - 405.5 1 2 0 0.0006 14 0 0 0 9.38E+07 6.68E+07 - - - 6.4959 0.9994 221125_WJC_METTL3_EV_vs_WT_F02.18267.18267.2 0.00455 20-Oct R.ENVLFLTSGTR.R "sp|Q14244|MAP7_HUMAN,tr|A0A087WZ40|A0A087WZ40_HUMAN" 2 1235.651 0.75 17575 18267 2 1235.649662 618.8328 Ensconsin OS=Homo sapiens OX=9606 GN=MAP7 PE=1 SV=1 6.1 3291.1 - 981315 - - - -1.0836 - 1.8 0.33 - 264.8 1 2 0 -0.0013 11 0 0 0 1.54E+07 2.05E+07 - - - 3.0681 0.9567 221125_WJC_METTL3_EV_vs_WT_F02.18272.18272.2 0.00014 19/26 R.PSAAGINLMIGSTR[166.11].Y sp|Q08211|DHX9_HUMAN 1 1396.7372 1.2 17578 18272 2 1396.731637 699.3759 ATP-dependent RNA helicase A OS=Homo sapiens OX=9606 GN=DHX9 PE=1 SV=4 10.18 3291.8 - 3.88E+06 - - - -3.9857 - 3.52 0.477 - 1163.5 1 1 0 -0.0056 14 0 0 0 7.58E+07 6.31E+07 - - - 5.7204 0.9923 221125_WJC_METTL3_EV_vs_WT_F02.18273.18273.3 0.0103 Dec-60 K.YVVVTGITPTPLGEGK[136.11].S "sp|P11586|C1TC_HUMAN,tr|F5H2F4|F5H2F4_HUMAN,tr|V9GZ78|V9GZ78_HUMAN,tr|V9GYY3|V9GYY3_HUMAN,tr|A0A494C1T2|A0A494C1T2_HUMAN" 5 1637.912 1.68 17579 18273 3 1637.917758 546.9779 "C-1-tetrahydrofolate synthase, cytoplasmic OS=Homo sapiens OX=9606 GN=MTHFD1 PE=1 SV=4" 6 3291.8 - 1.53E+06 - - - 3.5313 - 1.855 0.266 - 108.4 1 2 0 0.0058 16 0 0 0 3.11E+07 1.86E+07 - - - 3.0894 0.9999 221125_WJC_METTL3_EV_vs_WT_F02.18278.18278.3 0.000206 15/60 K.YVVVTGITPTPLGEGK.S "sp|P11586|C1TC_HUMAN,tr|F5H2F4|F5H2F4_HUMAN,tr|V9GZ78|V9GZ78_HUMAN,tr|V9GYY3|V9GYY3_HUMAN,tr|A0A494C1T2|A0A494C1T2_HUMAN" 5 1629.8978 1.68 17582 18278 3 1629.898592 544.3065 "C-1-tetrahydrofolate synthase, cytoplasmic OS=Homo sapiens OX=9606 GN=MTHFD1 PE=1 SV=4" 6 3292.5 - 1.97E+06 - - - 0.5019 - 2.353 0.372 - 283.9 1 2 0 0.0008 16 0 0 0 3.11E+07 1.86E+07 - - - 4.8828 0.9986 221125_WJC_METTL3_EV_vs_WT_F02.18279.18279.2 0.0613 22-Nov K.SLAVSGLGVIGR[166.11].D "sp|Q02880|TOP2B_HUMAN,tr|E9PCY5|E9PCY5_HUMAN" 2 1137.6745 0.79 17583 18279 2 1137.676015 569.8445 DNA topoisomerase 2-beta OS=Homo sapiens OX=9606 GN=TOP2B PE=1 SV=3 9.47 3292.6 - 2.23E+06 - - - 1.3071 - 1.747 0.268 - 223.7 1 2 0 0.0015 12 0 0 0 2.54E+07 3.20E+07 - - - 2.4879 0.9956 221125_WJC_METTL3_EV_vs_WT_F02.18280.18280.2 0.00638 14-Aug R.GFSLEELR.V "sp|P26373|RL13_HUMAN,tr|J3QSB4|J3QSB4_HUMAN" 2 949.4869 1.05 17584 18280 2 949.482928 475.7507 60S ribosomal protein L13 OS=Homo sapiens OX=9606 GN=RPL13 PE=1 SV=4 4.53 3292.7 - 1.61E+06 - - - -4.1791 - 1.606 0.371 - 291.3 1 2 0 -0.004 8 0 0 0 2.62E+08 2.49E+08 - - - 3.2088 0.9992 221125_WJC_METTL3_EV_vs_WT_F02.18281.18281.2 0.00161 14-Jun K.DYEVELLR.F "sp|P17480|UBF1_HUMAN,tr|E9PKP7|E9PKP7_HUMAN" 2 1035.5237 2.25 17585 18281 2 1035.521989 518.7691 Nucleolar transcription factor 1 OS=Homo sapiens OX=9606 GN=UBTF PE=1 SV=1 4.14 3292.9 - 972555 - - - -1.6291 - 1.476 0.391 - 135.6 1 2 0 -0.0017 8 0 0 0 2.47E+07 1.10E+07 - - - 3.1026 0.9998 221125_WJC_METTL3_EV_vs_WT_F02.18282.18282.2 0.000112 13/20 K.GEIEAELC[160.03]WAK.K "sp|Q15643|TRIPB_HUMAN,tr|H0YJ97|H0YJ97_HUMAN" 2 1304.6071 1.08 17586 18282 2 1304.60801 653.3108 Thyroid receptor-interacting protein 11 OS=Homo sapiens OX=9606 GN=TRIP11 PE=1 SV=3 4.25 3293 - 956765 - - - 0.7067 - 2.335 0.409 - 650.2 1 2 0 0.0009 11 0 0 0 3.02E+07 2.79E+07 - - - 4.3557 1 221125_WJC_METTL3_EV_vs_WT_F02.18285.18285.3 7.51E-07 14/56 R.IIDVVYNASNNELVR.T "sp|P62241|RS8_HUMAN,tr|Q5JR95|Q5JR95_HUMAN" 2 1717.8999 1 17587 18285 3 1717.896778 573.6406 40S ribosomal protein S8 OS=Homo sapiens OX=9606 GN=RPS8 PE=1 SV=2 4.37 3293.4 - 8.57E+06 - - - -1.8168 - 2.712 0.579 - 264.3 1 2 0 -0.0031 15 0 0 0 1.26E+08 1.27E+08 - - - 7.5977 0.9998 221125_WJC_METTL3_EV_vs_WT_F02.18288.18288.2 1.49E-06 15/24 K.QFAGYSEEVLDVR.F "sp|Q12788|TBL3_HUMAN,tr|J3KNP2|J3KNP2_HUMAN,tr|A0A087WYP7|A0A087WYP7_HUMAN" 3 1511.7256 1.3 17590 18288 2 1511.723198 756.8701 Transducin beta-like protein 3 OS=Homo sapiens OX=9606 GN=TBL3 PE=1 SV=2 4.14 3293.7 - 1.86E+06 - - - -1.6041 - 2.365 0.511 - 715.9 1 2 0 -0.0024 13 0 0 0 3.40E+07 2.61E+07 - - - 5.0237 0.9997 221125_WJC_METTL3_EV_vs_WT_F02.18289.18289.2 9.52E-07 15/24 R.ILAQSASVEEVFR.L "sp|Q15643|TRIPB_HUMAN,tr|H0YJ97|H0YJ97_HUMAN" 2 1447.7671 1.2 17591 18289 2 1447.770418 724.8908 Thyroid receptor-interacting protein 11 OS=Homo sapiens OX=9606 GN=TRIP11 PE=1 SV=3 4.53 3293.8 - 1.34E+06 - - - 2.2959 - 3.006 0.488 - 902 1 2 0 0.0033 13 0 0 0 4.91E+08 4.09E+08 - - - 5.4691 0.9243 221125_WJC_METTL3_EV_vs_WT_F02.18290.18290.2 0.185 12-Jun K.ELLIFNK[136.11].Q "sp|P09874|PARP1_HUMAN,tr|A0A7I2V5E9|A0A7I2V5E9_HUMAN,tr|A0A7I2V625|A0A7I2V625_HUMAN,tr|A0A7I2V3E1|A0A7I2V3E1_HUMAN" 4 883.5259 0.94 17592 18290 2 883.523459 442.7702 Poly [ADP-ribose] polymerase 1 OS=Homo sapiens OX=9606 GN=PARP1 PE=1 SV=4 6.1 3294 - 1.09E+06 - - - -2.7107 - 1.365 0.009 - 128.6 1 2 0 -0.0024 7 0 0 0 2.73E+07 2.89E+07 - - - 0.0926 0.9992 221125_WJC_METTL3_EV_vs_WT_F02.18293.18293.2 0.0222 14-Jul R.GFSLEELR[166.11].V "sp|P26373|RL13_HUMAN,tr|J3QSB4|J3QSB4_HUMAN" 2 959.4952 1.05 17593 18293 2 959.495363 480.7549 60S ribosomal protein L13 OS=Homo sapiens OX=9606 GN=RPL13 PE=1 SV=4 4.53 3294.4 - 7.22E+06 - - - 0.2053 - 1.471 0.322 - 210.5 1 2 0 0.0002 8 0 0 0 2.62E+08 2.49E+08 - - - 2.5832 0.9986 221125_WJC_METTL3_EV_vs_WT_F02.18295.18295.2 0.000348 20-Oct K.GEIEAELC[160.03]WAK[136.11].K "sp|Q15643|TRIPB_HUMAN,tr|H0YJ97|H0YJ97_HUMAN" 2 1312.6213 1.41 17595 18295 2 1312.616939 657.3179 Thyroid receptor-interacting protein 11 OS=Homo sapiens OX=9606 GN=TRIP11 PE=1 SV=3 4.25 3294.5 - 2.02E+06 - - - -3.3132 - 2.094 0.379 - 398.3 1 2 0 -0.0043 11 0 0 0 4.12E+07 2.91E+07 - - - 3.8383 0.9999 221125_WJC_METTL3_EV_vs_WT_F02.18296.18296.3 0.00293 20/48 R.ALYYLQIHPQELR.Q "sp|Q16531|DDB1_HUMAN,tr|A0A7P0TAK7|A0A7P0TAK7_HUMAN,tr|A0A7P0T870|A0A7P0T870_HUMAN,tr|A0A7P0TB30|A0A7P0TB30_HUMAN,tr|A0A7P0Z3Z5|A0A7P0Z3Z5_HUMAN,tr|F5GY55|F5GY55_HUMAN,tr|A0A7P0Z4B9|A0A7P0Z4B9_HUMAN" 7 1642.8831 0.64 17596 18296 3 1642.882077 548.635 DNA damage-binding protein 1 OS=Homo sapiens OX=9606 GN=DDB1 PE=1 SV=1 6.79 3294.6 - 1.81E+06 - - - -0.6391 - 2.595 0.423 - 461.2 1 2 0 -0.001 13 0 0 0 2.68E+07 4.21E+07 - - - 5.8412 0.9998 221125_WJC_METTL3_EV_vs_WT_F02.18297.18297.2 5.47E-06 22-Oct K.SLAVSGLGVIGR.D "sp|Q02880|TOP2B_HUMAN,tr|E9PCY5|E9PCY5_HUMAN" 2 1127.6663 0.79 17597 18297 2 1127.667253 564.8404 DNA topoisomerase 2-beta OS=Homo sapiens OX=9606 GN=TOP2B PE=1 SV=3 9.47 3294.8 - 1.57E+06 - - - 0.8824 - 2.256 0.461 - 336.2 1 2 0 0.001 12 0 0 0 2.54E+07 3.20E+07 - - - 4.5863 0.9996 221125_WJC_METTL3_EV_vs_WT_F02.18298.18298.2 0.00638 22-Dec K.VFGAAPLENVVR[166.11].K "sp|Q16656|NRF1_HUMAN,tr|C9JP85|C9JP85_HUMAN" 2 1280.7116 2.17 17598 18298 2 1280.709339 641.3631 Nuclear respiratory factor 1 OS=Homo sapiens OX=9606 GN=NRF1 PE=1 SV=1 5.97 3294.9 - 1.53E+06 - - - -1.7974 - 2.091 0.391 - 460.3 1 2 0 -0.0023 12 0 0 0 1.97E+08 9.09E+07 - - - 3.8691 0.9282 221125_WJC_METTL3_EV_vs_WT_F02.18300.18300.2 1.6 12-Jun K.DLTEYLK[136.11].V "sp|Q29RF7|PDS5A_HUMAN,sp|Q9NTI5|PDS5B_HUMAN" 2 888.4684 1.05 17600 18300 2 888.466559 445.2415 Sister chromatid cohesion protein PDS5 homolog A OS=Homo sapiens OX=9606 GN=PDS5A PE=1 SV=1 4.37 3295.2 - 934123 - - - -2.071 - 1.294 0.015 - 130.7 2 2 0 -0.0018 7 0 0 0 1.70E+07 1.61E+07 - - - -0.1666 0.963 221125_WJC_METTL3_EV_vs_WT_F02.18303.18303.2 0.00246 18-Aug L.TIDDGIFEVK[136.11].A "sp|P0DMV8|HS71A_HUMAN,sp|P34931|HS71L_HUMAN,sp|P0DMV9|HS71B_HUMAN,tr|Q53FA3|Q53FA3_HUMAN,tr|V9GZ37|V9GZ37_HUMAN,tr|A0A0G2JIW1|A0A0G2JIW1_HUMAN" 6 1143.5903 0.15 17601 18303 2 1143.589423 572.8024 Heat shock 70 kDa protein 1A OS=Homo sapiens OX=9606 GN=HSPA1A PE=1 SV=1 4.03 3295.6 - 2.22E+07 - - - -0.7713 - 1.503 0.365 - 109.2 1 1 0 -0.0009 10 0 0 0 2.42E+08 1.64E+09 - - - 2.874 1 221125_WJC_METTL3_EV_vs_WT_F02.18304.18304.2 1.74E-08 14/24 R.ILAQSASVEEVFR[166.11].L "sp|Q15643|TRIPB_HUMAN,tr|H0YJ97|H0YJ97_HUMAN" 2 1457.7754 1.2 17602 18304 2 1457.773477 729.895 Thyroid receptor-interacting protein 11 OS=Homo sapiens OX=9606 GN=TRIP11 PE=1 SV=3 4.53 3295.6 - 5.50E+06 - - - -1.2944 - 2.998 0.577 - 766.7 1 2 0 -0.0019 13 0 0 0 4.89E+08 4.09E+08 - - - 6.12 0.9798 221125_WJC_METTL3_EV_vs_WT_F02.18306.18306.2 0.0005 18-Nov L.TIDDGIFEVK.A "sp|P0DMV8|HS71A_HUMAN,sp|P34931|HS71L_HUMAN,sp|P0DMV9|HS71B_HUMAN,tr|Q53FA3|Q53FA3_HUMAN,tr|V9GZ37|V9GZ37_HUMAN,tr|A0A0G2JIW1|A0A0G2JIW1_HUMAN" 6 1135.5761 0.15 17604 18306 2 1135.577554 568.7953 Heat shock 70 kDa protein 1A OS=Homo sapiens OX=9606 GN=HSPA1A PE=1 SV=1 4.03 3295.7 - 2.83E+06 - - - 1.276 - 1.807 0.437 - 243.6 1 1 0 0.0014 10 0 0 0 2.43E+08 1.65E+09 - - - 3.9198 0.9172 221125_WJC_METTL3_EV_vs_WT_F02.18307.18307.2 0.00763 30-Oct R.LGSAGGLGSTLGGSSY.S "sp|Q04695|K1C17_HUMAN,tr|K7EPJ9|K7EPJ9_HUMAN" 2 1382.6678 - 17605 18307 2 1382.666996 692.3412 "Keratin, type I cytoskeletal 17 OS=Homo sapiens OX=9606 GN=KRT17 PE=1 SV=2" 5.52 3295.8 - 2.48E+06 - - - -0.5627 - 1.488 0.276 - 187.7 1 1 0 -0.0008 16 0 0 0 - - - - - 2.0564 0.9958 221125_WJC_METTL3_EV_vs_WT_F02.18309.18309.2 0.0213 20-Dec R.FLGDYVENLNK[136.11].S sp|Q709C8|VP13C_HUMAN 1 1318.6649 0.75 17607 18309 2 1318.65887 660.3397 Vacuolar protein sorting-associated protein 13C OS=Homo sapiens OX=9606 GN=VPS13C PE=1 SV=1 4.37 3296.1 - 1.26E+06 - - - -4.5478 - 2.016 0.356 - 287.7 1 2 0 -0.006 11 0 0 0 1.26E+07 1.68E+07 - - - 3.5652 0.9952 221125_WJC_METTL3_EV_vs_WT_F02.18310.18310.2 0.0595 12-May R.WADIFSK.Y sp|Q6P4A8|PLBL1_HUMAN 1 865.4334 999 17608 18310 2 865.434412 433.724 Phospholipase B-like 1 OS=Homo sapiens OX=9606 GN=PLBD1 PE=1 SV=2 5.84 3296.2 - 1.14E+06 - - - 1.1647 - 1.234 0.229 - 102.6 1 2 0 0.001 7 0 0 0 1.31E+07 0.00E+00 - - - 1.3983 0.9759 221125_WJC_METTL3_EV_vs_WT_F02.18315.18315.2 0.0441 12-Jun K.ELLIFNK.Q "sp|P09874|PARP1_HUMAN,tr|A0A7I2V5E9|A0A7I2V5E9_HUMAN,tr|A0A7I2V625|A0A7I2V625_HUMAN,tr|A0A7I2V3E1|A0A7I2V3E1_HUMAN" 4 875.5117 0.94 17611 18315 2 875.511355 438.7631 Poly [ADP-ribose] polymerase 1 OS=Homo sapiens OX=9606 GN=PARP1 PE=1 SV=4 6.1 3296.7 - 2.35E+06 - - - -0.3415 - 1.308 0.02 - 137.8 1 2 0 -0.0003 7 0 0 0 2.73E+07 2.89E+07 - - - 0.0394 0.9998 221125_WJC_METTL3_EV_vs_WT_F02.18317.18317.2 0.000533 18-Dec R.TDVLTGLSIR[166.11].L "sp|Q6SPF0|SAMD1_HUMAN,tr|E9PIW9|E9PIW9_HUMAN,tr|F8WDT5|F8WDT5_HUMAN" 3 1083.6163 2.13 17613 18317 2 1083.616731 542.8154 Sterile alpha motif domain-containing protein 1 OS=Homo sapiens OX=9606 GN=SAMD1 PE=1 SV=1 5.5 3296.9 - 1.69E+06 - - - 0.3571 - 2.405 0.354 - 704.9 1 2 0 0.0004 10 0 0 0 7.02E+07 3.30E+07 - - - 4.105 0.9997 221125_WJC_METTL3_EV_vs_WT_F02.18322.18322.2 2.86E-07 13/24 K.GYLGPEQLPDC[160.03]LK[136.11].G sp|P40926|MDHM_HUMAN 1 1496.7425 1.11 17618 18322 2 1496.739043 749.3785 "Malate dehydrogenase, mitochondrial OS=Homo sapiens OX=9606 GN=MDH2 PE=1 SV=3" 4.37 3297.5 - 624691 - - - -2.287 - 2.248 0.494 - 546.9 1 2 0 -0.0034 13 0 0 0 6.86E+06 6.19E+06 - - - 4.7676 0.9999 221125_WJC_METTL3_EV_vs_WT_F02.18327.18327.2 5.89E-05 22-Nov K.ADLINNLGTIAK[136.11].F "sp|Q58FF8|H90B2_HUMAN,sp|P08238|HS90B_HUMAN,sp|P07900|HS90A_HUMAN,sp|Q14568|HS902_HUMAN" 4 1249.7122 0.84 17622 18327 2 1249.712535 625.8634 Putative heat shock protein HSP 90-beta 2 OS=Homo sapiens OX=9606 GN=HSP90AB2P PE=1 SV=2 5.88 3298 - 4.67E+06 - - - 0.3065 - 2.556 0.507 - 570.1 1 2 0 0.0004 12 0 0 0 8.03E+08 9.53E+08 - - - 5.2548 0.9998 221125_WJC_METTL3_EV_vs_WT_F02.18328.18328.3 0.00109 Nov-48 R.ILAQSASVEEVFR.L "sp|Q15643|TRIPB_HUMAN,tr|H0YJ97|H0YJ97_HUMAN" 2 1447.7671 1.25 17623 18328 3 1447.768822 483.5963 Thyroid receptor-interacting protein 11 OS=Homo sapiens OX=9606 GN=TRIP11 PE=1 SV=3 4.53 3298.1 - 2.26E+06 - - - 1.1936 - 2.183 0.371 - 195.7 1 2 0 0.0017 13 0 0 0 3.36E+07 2.68E+07 - - - 4.7925 0.9995 221125_WJC_METTL3_EV_vs_WT_F02.18329.18329.2 0.0205 16-Sep K.MMLDDIVSR[166.11].G "sp|Q92945|FUBP2_HUMAN,tr|M0R0I5|M0R0I5_HUMAN,tr|M0QYH3|M0QYH3_HUMAN,tr|M0R0C6|M0R0C6_HUMAN,tr|M0QXW7|M0QXW7_HUMAN,tr|A0A087WTP3|A0A087WTP3_HUMAN" 6 1088.5234 0.69 17624 18329 2 1088.52244 545.269 Far upstream element-binding protein 2 OS=Homo sapiens OX=9606 GN=KHSRP PE=1 SV=4 4.21 3298.1 - 2.18E+06 - - - -0.8562 - 1.685 0.36 - 285.4 1 2 0 -0.0009 9 0 0 0 3.64E+07 5.26E+07 - - - 3.2092 0.999 221125_WJC_METTL3_EV_vs_WT_F02.18330.18330.2 0.0135 18-Aug K.TGIPLNVLPK[136.11].K sp|Q96GA3|LTV1_HUMAN 1 1058.6579 0.73 17625 18330 2 1058.658206 530.3362 Protein LTV1 homolog OS=Homo sapiens OX=9606 GN=LTV1 PE=1 SV=1 8.41 3298.3 - 2.02E+06 - - - 0.2598 - 1.566 0.281 - 110.1 1 2 0 0.0003 10 0 0 0 1.93E+07 2.64E+07 - - - 2.3683 1 221125_WJC_METTL3_EV_vs_WT_F02.18331.18331.3 4.60E-06 13/48 R.ILAQSASVEEVFR[166.11].L "sp|Q15643|TRIPB_HUMAN,tr|H0YJ97|H0YJ97_HUMAN" 2 1457.7754 1.29 17626 18331 3 1457.774787 486.9324 Thyroid receptor-interacting protein 11 OS=Homo sapiens OX=9606 GN=TRIP11 PE=1 SV=3 4.53 3298.3 - 2.00E+06 - - - -0.3958 - 2.647 0.451 - 312.9 1 2 0 -0.0006 13 0 0 0 3.36E+07 2.61E+07 - - - 6.2073 0.9993 221125_WJC_METTL3_EV_vs_WT_F02.18332.18332.2 0.475 16-Oct K.MMLDDIVSR.G "sp|Q92945|FUBP2_HUMAN,tr|M0R0I5|M0R0I5_HUMAN,tr|M0QYH3|M0QYH3_HUMAN,tr|M0R0C6|M0R0C6_HUMAN,tr|M0QXW7|M0QXW7_HUMAN,tr|A0A087WTP3|A0A087WTP3_HUMAN" 6 1078.5151 0.69 17627 18332 2 1078.512682 540.2648 Far upstream element-binding protein 2 OS=Homo sapiens OX=9606 GN=KHSRP PE=1 SV=4 4.21 3298.4 - 1.77E+06 - - - -2.2438 - 1.911 0.383 - 490.2 1 2 0 -0.0024 9 0 0 0 3.64E+07 5.26E+07 - - - 3.7427 0.9999 221125_WJC_METTL3_EV_vs_WT_F02.18334.18334.3 6.36E-05 15/48 K.LGWVRPDLGELSK.V sp|P51970|NDUA8_HUMAN 1 1468.8038 1.58 17629 18334 3 1468.802795 490.6085 NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 8 OS=Homo sapiens OX=9606 GN=NDUFA8 PE=1 SV=3 6.07 3298.7 - 1.39E+06 - - - -0.6938 - 2.601 0.391 - 393.3 1 2 0 -0.001 13 0 0 0 2.89E+07 1.84E+07 - - - 5.4907 0.9998 221125_WJC_METTL3_EV_vs_WT_F02.18335.18335.2 0.00123 13/28 K.VLALPEPSPAAPTLR.S "sp|Q15149|PLEC_HUMAN,tr|H0YDN1|H0YDN1_HUMAN" 2 1530.877 2.11 17630 18335 2 1530.87722 766.4458 Plectin OS=Homo sapiens OX=9606 GN=PLEC PE=1 SV=3 5.97 3298.8 - 782271 - - - 0.1574 - 2.323 0.391 - 430.8 1 2 0 0.0002 15 0 0 0 3.67E+07 1.74E+07 - - - 4.0011 0.8997 221125_WJC_METTL3_EV_vs_WT_F02.18336.18336.2 0.815 20-Sep K.IGIVGLPNVGK.S "sp|Q9NTK5|OLA1_HUMAN,tr|C9JTK6|C9JTK6_HUMAN,tr|J3KQ32|J3KQ32_HUMAN" 3 1065.6546 0.67 17631 18336 2 1065.648433 533.8346 Obg-like ATPase 1 OS=Homo sapiens OX=9606 GN=OLA1 PE=1 SV=2 8.75 3298.9 - 717223 - - - -5.8152 - 1.544 0.163 - 127.6 1 2 0 -0.0062 11 0 0 0 1.82E+07 2.71E+07 - - - 1.4181 0.9976 221125_WJC_METTL3_EV_vs_WT_F02.18339.18339.2 0.00685 24-Sep K.VIASELGSMPELK.K "sp|Q9P2J5|SYLC_HUMAN,tr|A0A6I8PIV1|A0A6I8PIV1_HUMAN,tr|A0A6I8PRS0|A0A6I8PRS0_HUMAN,tr|A0A6I8PLB8|A0A6I8PLB8_HUMAN,tr|A0A6I8PIT3|A0A6I8PIT3_HUMAN,tr|A0A6I8PLB3|A0A6I8PLB3_HUMAN,tr|A0A6I8PS05|A0A6I8PS05_HUMAN,tr|B4DER1|B4DER1_HUMAN,tr|A0A6I8PL42|A0A6I8PL42_HUMAN" 9 1372.7272 1.32 17634 18339 2 1372.723818 687.3709 "Leucine--tRNA ligase, cytoplasmic OS=Homo sapiens OX=9606 GN=LARS1 PE=1 SV=2" 4.53 3299.3 - 452989 - - - -2.4659 - 1.577 0.32 - 100.7 1 2 0 -0.0034 13 0 0 0 1.78E+07 1.35E+07 - - - 2.5726 0.9998 221125_WJC_METTL3_EV_vs_WT_F02.18341.18341.2 3.94E-08 13/24 K.GYLGPEQLPDC[160.03]LK.G sp|P40926|MDHM_HUMAN 1 1488.7283 1.84 17635 18341 2 1488.72559 745.3714 "Malate dehydrogenase, mitochondrial OS=Homo sapiens OX=9606 GN=MDH2 PE=1 SV=3" 4.37 3299.5 - 924694 - - - -1.7975 - 2.289 0.525 - 282.6 1 2 0 -0.0027 13 0 0 0 2.02E+07 1.10E+07 - - - 5.0432 0.9999 221125_WJC_METTL3_EV_vs_WT_F02.18343.18343.2 4.63E-05 22-Nov K.ADLINNLGTIAK.F "sp|Q58FF8|H90B2_HUMAN,sp|P08238|HS90B_HUMAN,sp|P07900|HS90A_HUMAN,sp|Q14568|HS902_HUMAN" 4 1241.698 0.86 17636 18343 2 1241.697772 621.8563 Putative heat shock protein HSP 90-beta 2 OS=Homo sapiens OX=9606 GN=HSP90AB2P PE=1 SV=2 5.88 3299.7 - 1.40E+07 - - - -0.145 - 2.527 0.443 - 329.9 1 2 0 -0.0002 12 0 0 0 8.19E+08 9.53E+08 - - - 4.7521 1 221125_WJC_METTL3_EV_vs_WT_F02.18345.18345.3 9.42E-08 20/56 K.LGAVYDVSHYNALLK.V "sp|P42704|LPPRC_HUMAN,tr|A0A804HI14|A0A804HI14_HUMAN,tr|A0A804HL40|A0A804HL40_HUMAN,tr|A0A804HKJ0|A0A804HKJ0_HUMAN,tr|A0A804HKR3|A0A804HKR3_HUMAN,tr|A0A0C4DG06|A0A0C4DG06_HUMAN,tr|A0A804HIN4|A0A804HIN4_HUMAN,tr|A0A804HLG8|A0A804HLG8_HUMAN,tr|A0A804HIV5|A0A804HIV5_HUMAN,tr|A0A804HHY9|A0A804HHY9_HUMAN,tr|A0A804HJH8|A0A804HJH8_HUMAN,tr|B8ZZ38|B8ZZ38_HUMAN,tr|A0A804HI40|A0A804HI40_HUMAN,tr|A0A804HJZ1|A0A804HJZ1_HUMAN,tr|C9JCA9|C9JCA9_HUMAN,tr|A0A804HIQ7|A0A804HIQ7_HUMAN,tr|A0A804HK30|A0A804HK30_HUMAN,tr|A0A804HKI2|A0A804HKI2_HUMAN,tr|A0A804HKR5|A0A804HKR5_HUMAN,tr|A0A804HKX0|A0A804HKX0_HUMAN,tr|A0A804HIG4|A0A804HIG4_HUMAN,tr|A0A804HK02|A0A804HK02_HUMAN" 22 1661.8777 0.26 17638 18345 3 1661.878803 554.9665 "Leucine-rich PPR motif-containing protein, mitochondrial OS=Homo sapiens OX=9606 GN=LRPPRC PE=1 SV=3" 6.74 3299.8 - 2.49E+06 - - - 0.6595 - 3.706 0.561 - 556.2 1 2 0 0.0011 15 0 0 0 2.41E+07 9.11E+07 - - - 8.2124 0.9998 221125_WJC_METTL3_EV_vs_WT_F02.18346.18346.2 1.60E-06 18-Nov K.DYLAHSSMDF.- sp|Q9UJV9|DDX41_HUMAN 1 1184.4808 - 17639 18346 2 1184.478682 593.2477 Probable ATP-dependent RNA helicase DDX41 OS=Homo sapiens OX=9606 GN=DDX41 PE=1 SV=2 4.2 3299.9 - 2.46E+06 - - - -1.8092 - 1.86 0.643 - 287.2 1 2 0 -0.0021 10 0 0 0 - - - - - 5.5217 0.9997 221125_WJC_METTL3_EV_vs_WT_F02.18348.18348.3 0.045 13/48 R.ALYYLQIHPQELR[166.11].Q "sp|Q16531|DDB1_HUMAN,tr|A0A7P0TAK7|A0A7P0TAK7_HUMAN,tr|A0A7P0T870|A0A7P0T870_HUMAN,tr|A0A7P0TB30|A0A7P0TB30_HUMAN,tr|A0A7P0Z3Z5|A0A7P0Z3Z5_HUMAN,tr|F5GY55|F5GY55_HUMAN,tr|A0A7P0Z4B9|A0A7P0Z4B9_HUMAN" 7 1652.8914 0.7 17641 18348 3 1652.890246 551.9711 DNA damage-binding protein 1 OS=Homo sapiens OX=9606 GN=DDB1 PE=1 SV=1 6.79 3300 - 2.03E+06 - - - -0.6964 - 2.14 0.324 - 188.9 1 2 0 -0.0011 13 0 0 0 2.68E+07 3.85E+07 - - - 4.2147 0.9946 221125_WJC_METTL3_EV_vs_WT_F02.18349.18349.2 0.00526 16-Sep K.LGIFENLNK[136.11].H "sp|Q13613|MTMR1_HUMAN,tr|E9PIH9|E9PIH9_HUMAN,tr|Q8NEC6|Q8NEC6_HUMAN,tr|F8WA39|F8WA39_HUMAN,tr|H0YDX3|H0YDX3_HUMAN" 5 1054.5902 0.68 17642 18349 2 1054.595074 528.3024 Myotubularin-related protein 1 OS=Homo sapiens OX=9606 GN=MTMR1 PE=1 SV=4 6 3300.1 - 1.85E+06 - - - 4.5781 - 1.899 0.331 - 159.4 1 2 0 0.0048 9 0 0 0 1.57E+07 2.30E+07 - - - 3.3396 1 221125_WJC_METTL3_EV_vs_WT_F02.18352.18352.2 1.09E-08 15/28 R.NGSFGVLVATNVAAR[166.11].G sp|Q9NR30|DDX21_HUMAN 1 1484.7975 0.32 17645 18352 2 1484.800222 743.406 Nucleolar RNA helicase 2 OS=Homo sapiens OX=9606 GN=DDX21 PE=1 SV=5 9.75 3300.4 - 1.33E+06 - - - 1.8359 - 2.616 0.629 - 738.8 1 2 0 0.0027 15 0 0 0 5.66E+06 1.79E+07 - - - 6.0502 1 221125_WJC_METTL3_EV_vs_WT_F02.18353.18353.2 2.53E-06 15/28 R.MGFTEVTPVTGASLR[166.11].R "sp|P55265|DSRAD_HUMAN,tr|A0A3B3ISU1|A0A3B3ISU1_HUMAN,tr|A0A7P0Z4K3|A0A7P0Z4K3_HUMAN,tr|A0A7P0Z4F9|A0A7P0Z4F9_HUMAN" 4 1574.8002 0.74 17646 18353 2 1574.800543 788.4074 Double-stranded RNA-specific adenosine deaminase OS=Homo sapiens OX=9606 GN=ADAR PE=1 SV=4 5.75 3300.6 - 1.05E+06 - - - 0.2191 - 3.137 0.548 - 430.3 1 2 0 0.0003 15 0 0 0 3.65E+07 4.94E+07 - - - 5.8992 0.9999 221125_WJC_METTL3_EV_vs_WT_F02.18354.18354.2 0.000154 14/28 K.GIITAVEPSTPTVLR[166.11].S "sp|Q9Y618|NCOR2_HUMAN,tr|C9J7T7|C9J7T7_HUMAN,tr|C9JE98|C9JE98_HUMAN,tr|C9J0Q5|C9J0Q5_HUMAN,tr|H7C0P3|H7C0P3_HUMAN,tr|A0A384DVL6|A0A384DVL6_HUMAN" 6 1562.8907 2.56 17647 18354 2 1562.889441 782.4526 Nuclear receptor corepressor 2 OS=Homo sapiens OX=9606 GN=NCOR2 PE=1 SV=3 6 3300.7 - 912313 - - - -0.8235 - 2.911 0.471 - 405.9 1 2 0 -0.0013 15 0 0 0 5.36E+07 2.10E+07 - - - 5.1464 0.9995 221125_WJC_METTL3_EV_vs_WT_F02.18357.18357.2 4.20E-07 14/26 K.LIAEQTLQENLIEK[136.11].G sp|Q5UIP0|RIF1_HUMAN 1 1648.9127 0.95 17650 18357 2 1648.907419 825.4636 Telomere-associated protein RIF1 OS=Homo sapiens OX=9606 GN=RIF1 PE=1 SV=2 4.25 3301.1 - 508480 - - - -3.2039 - 2.981 0.5 - 505.1 1 2 0 -0.0053 14 0 0 0 1.85E+07 1.95E+07 - - - 5.4733 0.9805 221125_WJC_METTL3_EV_vs_WT_F02.18358.18358.2 0.0413 13/28 K.LGAVYDVSHYNALLK[136.11].V "sp|P42704|LPPRC_HUMAN,tr|A0A804HI14|A0A804HI14_HUMAN,tr|A0A804HL40|A0A804HL40_HUMAN,tr|A0A804HKJ0|A0A804HKJ0_HUMAN,tr|A0A804HKR3|A0A804HKR3_HUMAN,tr|A0A0C4DG06|A0A0C4DG06_HUMAN,tr|A0A804HIN4|A0A804HIN4_HUMAN,tr|A0A804HLG8|A0A804HLG8_HUMAN,tr|A0A804HIV5|A0A804HIV5_HUMAN,tr|A0A804HHY9|A0A804HHY9_HUMAN,tr|A0A804HJH8|A0A804HJH8_HUMAN,tr|B8ZZ38|B8ZZ38_HUMAN,tr|A0A804HI40|A0A804HI40_HUMAN,tr|A0A804HJZ1|A0A804HJZ1_HUMAN,tr|C9JCA9|C9JCA9_HUMAN,tr|A0A804HIQ7|A0A804HIQ7_HUMAN,tr|A0A804HK30|A0A804HK30_HUMAN,tr|A0A804HKI2|A0A804HKI2_HUMAN,tr|A0A804HKR5|A0A804HKR5_HUMAN,tr|A0A804HKX0|A0A804HKX0_HUMAN,tr|A0A804HIG4|A0A804HIG4_HUMAN,tr|A0A804HK02|A0A804HK02_HUMAN" 22 1669.8919 0.29 17651 18358 2 1669.900329 835.9532 "Leucine-rich PPR motif-containing protein, mitochondrial OS=Homo sapiens OX=9606 GN=LRPPRC PE=1 SV=3" 6.74 3301.2 - 506407 - - - 5.0434 - 1.899 0.241 - 459.2 1 2 0 0.0084 15 0 0 0 1.37E+06 4.80E+06 - - - 2.3951 0.9986 221125_WJC_METTL3_EV_vs_WT_F02.18361.18361.2 0.0046 18-Nov R.EQLAIAEFAR[166.11].S "sp|P17987|TCPA_HUMAN,tr|F5H282|F5H282_HUMAN,tr|E7EQR6|E7EQR6_HUMAN" 3 1156.6116 0.58 17652 18361 2 1156.608027 579.3131 T-complex protein 1 subunit alpha OS=Homo sapiens OX=9606 GN=TCP1 PE=1 SV=1 4.53 3301.6 - 7.94E+07 - - - -3.0831 - 2.136 0.329 - 665.4 1 2 0 -0.0036 10 0 0 0 9.39E+08 1.62E+09 - - - 3.5883 1 221125_WJC_METTL3_EV_vs_WT_F02.18362.18362.3 1.51E-05 13/44 R.GYISPYFINTSK[136.11].G "sp|P10809|CH60_HUMAN,tr|A0A7I2V2X6|A0A7I2V2X6_HUMAN,tr|A0A7I2V599|A0A7I2V599_HUMAN,tr|A0A7I2YQ71|A0A7I2YQ71_HUMAN,tr|E7ESH4|E7ESH4_HUMAN,tr|A0A7I2V5M1|A0A7I2V5M1_HUMAN,tr|A0A7I2V5K3|A0A7I2V5K3_HUMAN,tr|A0A7I2V369|A0A7I2V369_HUMAN" 8 1396.7118 1.34 17653 18362 3 1396.710796 466.5779 "60 kDa heat shock protein, mitochondrial OS=Homo sapiens OX=9606 GN=HSPD1 PE=1 SV=2" 8.5 3301.7 - 2.76E+06 - - - -0.731 - 2.318 0.519 - 190.9 1 2 0 -0.001 12 0 0 0 2.17E+08 1.61E+08 - - - 6.6564 0.9176 221125_WJC_METTL3_EV_vs_WT_F02.18363.18363.2 0.0104 14-Jun K.QTQIFTTY.S "sp|P0DMV8|HS71A_HUMAN,sp|P34931|HS71L_HUMAN,sp|P0DMV9|HS71B_HUMAN,tr|Q53FA3|Q53FA3_HUMAN,tr|V9GZ37|V9GZ37_HUMAN,tr|A0A0G2JIW1|A0A0G2JIW1_HUMAN" 6 1000.4866 - 17654 18363 2 1000.486558 501.2506 Heat shock 70 kDa protein 1A OS=Homo sapiens OX=9606 GN=HSPA1A PE=1 SV=1 5.52 3301.7 - 4.40E+06 - - - -0.004 - 1.223 0.322 - 171.2 1 1 0 0 8 0 0 0 - - - - - 2.0264 0.9999 221125_WJC_METTL3_EV_vs_WT_F02.18364.18364.3 3.80E-06 13/44 R.GYISPYFINTSK.G "sp|P10809|CH60_HUMAN,tr|A0A7I2V2X6|A0A7I2V2X6_HUMAN,tr|A0A7I2V599|A0A7I2V599_HUMAN,tr|A0A7I2YQ71|A0A7I2YQ71_HUMAN,tr|E7ESH4|E7ESH4_HUMAN,tr|A0A7I2V5M1|A0A7I2V5M1_HUMAN,tr|A0A7I2V5K3|A0A7I2V5K3_HUMAN,tr|A0A7I2V369|A0A7I2V369_HUMAN" 8 1388.6976 1.37 17655 18364 3 1388.697147 463.9065 "60 kDa heat shock protein, mitochondrial OS=Homo sapiens OX=9606 GN=HSPD1 PE=1 SV=2" 8.5 3301.8 - 4.00E+06 - - - -0.3384 - 1.923 0.482 - 166.5 1 2 0 -0.0005 12 0 0 0 2.21E+08 1.61E+08 - - - 5.7262 0.999 221125_WJC_METTL3_EV_vs_WT_F02.18365.18365.2 0.00456 16-Sep K.AEIELFVNR.L sp|Q99805|TM9S2_HUMAN 1 1089.5819 0.96 17656 18365 2 1089.583672 545.7982 Transmembrane 9 superfamily member 2 OS=Homo sapiens OX=9606 GN=TM9SF2 PE=1 SV=1 4.53 3301.8 - 3.70E+06 - - - 1.6639 - 1.963 0.264 - 267.9 1 2 0 0.0018 9 0 0 0 3.26E+07 3.39E+07 - - - 2.9416 0.9998 221125_WJC_METTL3_EV_vs_WT_F02.18366.18366.2 4.37E-05 14/28 K.GIITAVEPSTPTVLR.S "sp|Q9Y618|NCOR2_HUMAN,tr|C9J7T7|C9J7T7_HUMAN,tr|C9JE98|C9JE98_HUMAN,tr|C9J0Q5|C9J0Q5_HUMAN,tr|H7C0P3|H7C0P3_HUMAN,tr|A0A384DVL6|A0A384DVL6_HUMAN" 6 1552.8825 2.56 17657 18366 2 1552.881611 777.4485 Nuclear receptor corepressor 2 OS=Homo sapiens OX=9606 GN=NCOR2 PE=1 SV=3 6 3301.9 - 2.93E+06 - - - -0.5454 - 2.719 0.383 - 437.2 1 2 0 -0.0008 15 0 0 0 5.36E+07 2.10E+07 - - - 4.3288 0.9979 221125_WJC_METTL3_EV_vs_WT_F02.18367.18367.2 0.0187 16-Jul R.RDIEDIPYV.- "sp|Q96EI5|TCAL4_HUMAN,tr|A2RQR6|A2RQR6_HUMAN" 2 1118.5608 1.18 17658 18367 2 1118.561309 560.2877 Transcription elongation factor A protein-like 4 OS=Homo sapiens OX=9606 GN=TCEAL4 PE=1 SV=2 4.03 3301.9 - 2.02E+06 - - - 0.4649 - 1.287 0.276 - 105.9 1 2 0 0.0005 9 0 0 0 4.38E+07 3.70E+07 - - - 1.8093 0.9365 221125_WJC_METTL3_EV_vs_WT_F02.18372.18372.3 0.0111 Sep-44 R.SPSELFAQHIVT.L "sp|Q9Y2W1|TR150_HUMAN,tr|A0A3B3ITZ9|A0A3B3ITZ9_HUMAN" 2 1327.6772 - 17663 18372 3 1327.678035 443.5663 Thyroid hormone receptor-associated protein 3 OS=Homo sapiens OX=9606 GN=THRAP3 PE=1 SV=2 5.22 3302.6 - 592265 - - - 0.6169 - 1.625 0.336 - 74.1 1 1 0 0.0008 12 0 0 0 - - - - - 3.6316 1 221125_WJC_METTL3_EV_vs_WT_F02.18375.18375.2 2.40E-09 16/28 R.MGFTEVTPVTGASLR.R "sp|P55265|DSRAD_HUMAN,tr|A0A3B3ISU1|A0A3B3ISU1_HUMAN,tr|A0A7P0Z4K3|A0A7P0Z4K3_HUMAN,tr|A0A7P0Z4F9|A0A7P0Z4F9_HUMAN" 4 1564.7919 0.74 17664 18375 2 1564.791596 783.4032 Double-stranded RNA-specific adenosine deaminase OS=Homo sapiens OX=9606 GN=ADAR PE=1 SV=4 5.75 3303 - 2.34E+06 - - - -0.2122 - 3.123 0.613 - 616.9 1 2 0 -0.0003 15 0 0 0 3.65E+07 4.94E+07 - - - 6.3683 0.9939 221125_WJC_METTL3_EV_vs_WT_F02.18376.18376.2 7.84E-05 13/20 Q.WGTLTDC[160.03]VVMR.D "sp|Q32P51|RA1L2_HUMAN,sp|P51991|ROA3_HUMAN,sp|P09651|ROA1_HUMAN,tr|A0A7I2V5D8|A0A7I2V5D8_HUMAN,tr|F8W646|F8W646_HUMAN,tr|A0A7I2V2R3|A0A7I2V2R3_HUMAN,tr|F8VZ49|F8VZ49_HUMAN,tr|A0A7I2V3R8|A0A7I2V3R8_HUMAN,tr|F8W6I7|F8W6I7_HUMAN,tr|A0A7I2V2L6|A0A7I2V2L6_HUMAN,tr|A0A7I2V4J6|A0A7I2V4J6_HUMAN,tr|A0A7I2V3W0|A0A7I2V3W0_HUMAN,tr|A0A7I2V4G0|A0A7I2V4G0_HUMAN,tr|A0A7I2V402|A0A7I2V402_HUMAN" 14 1336.6268 1.07 17665 18376 2 1336.626176 669.3207 Heterogeneous nuclear ribonucleoprotein A1-like 2 OS=Homo sapiens OX=9606 GN=HNRNPA1L2 PE=2 SV=2 5.83 3303.1 - 1.90E+06 - - - -0.4504 - 2.652 0.48 - 793.8 1 1 0 -0.0006 11 0 0 0 5.64E+07 5.28E+07 - - - 5.2245 0.9996 221125_WJC_METTL3_EV_vs_WT_F02.18377.18377.2 1.22 16-Dec K.RVLGLVLLR.G "sp|P63162|RSMN_HUMAN,sp|P14678|RSMB_HUMAN,tr|J3QLE5|J3QLE5_HUMAN" 3 1037.7073 0.77 17666 18377 2 1037.706699 519.8609 Small nuclear ribonucleoprotein-associated protein N OS=Homo sapiens OX=9606 GN=SNRPN PE=1 SV=1 12 3303.2 - 2.04E+06 - - - -0.6119 - 2.175 0.276 - 278.2 1 2 0 -0.0006 9 0 0 0 1.68E+08 2.19E+08 - - - 3.3273 0.9996 221125_WJC_METTL3_EV_vs_WT_F02.18379.18379.2 0.00217 13/28 K.VLALPEPSPAAPTLR[166.11].S "sp|Q15149|PLEC_HUMAN,tr|H0YDN1|H0YDN1_HUMAN" 2 1540.8852 2.11 17668 18379 2 1540.882759 771.4499 Plectin OS=Homo sapiens OX=9606 GN=PLEC PE=1 SV=3 5.97 3303.5 - 1.28E+06 - - - -1.616 - 2.376 0.355 - 459.3 1 2 0 -0.0025 15 0 0 0 3.67E+07 1.74E+07 - - - 3.7899 0.9992 221125_WJC_METTL3_EV_vs_WT_F02.18380.18380.2 9.25E-05 22-Oct K.VFLGNGISELSR[166.11].K sp|Q8TEA1|NSUN6_HUMAN 1 1300.7015 0.73 17669 18380 2 1300.70536 651.358 tRNA (cytosine(72)-C(5))-methyltransferase NSUN6 OS=Homo sapiens OX=9606 GN=NSUN6 PE=1 SV=1 5.97 3303.6 - 781385 - - - 2.9899 - 2.268 0.425 - 293.8 1 2 0 0.0039 12 0 0 0 1.39E+07 1.89E+07 - - - 4.3335 1 221125_WJC_METTL3_EV_vs_WT_F02.18382.18382.2 5.60E-06 14/22 R.SPSELFAQHIVT.L "sp|Q9Y2W1|TR150_HUMAN,tr|A0A3B3ITZ9|A0A3B3ITZ9_HUMAN" 2 1327.6772 - 17670 18382 2 1327.677135 664.8459 Thyroid hormone receptor-associated protein 3 OS=Homo sapiens OX=9606 GN=THRAP3 PE=1 SV=2 5.22 3303.8 - 5.72E+06 - - - -0.061 - 2.812 0.545 - 515.5 1 1 0 -0.0001 12 0 0 0 - - - - - 5.7867 0.9987 221125_WJC_METTL3_EV_vs_WT_F02.18384.18384.2 0.921 16-Oct K.R[166.11]VLGLVLLR[166.11].G "sp|P63162|RSMN_HUMAN,sp|P14678|RSMB_HUMAN,tr|J3QLE5|J3QLE5_HUMAN" 3 1057.7239 0.77 17671 18384 2 1057.722815 529.8692 Small nuclear ribonucleoprotein-associated protein N OS=Homo sapiens OX=9606 GN=SNRPN PE=1 SV=1 12 3304.1 - 5.74E+06 - - - -1.0012 - 1.791 0.209 - 171.1 1 2 0 -0.0011 9 0 0 0 1.68E+08 2.19E+08 - - - 2.2703 0.9998 221125_WJC_METTL3_EV_vs_WT_F02.18387.18387.2 5.84E-05 18-Oct R.NLPYVYIPSK[136.11].T "sp|Q9NX24|NHP2_HUMAN,tr|H0YC83|H0YC83_HUMAN,tr|D6RCB9|D6RCB9_HUMAN,tr|D6RC52|D6RC52_HUMAN" 4 1200.6634 1.26 17674 18387 2 1200.662926 601.339 H\ACA ribonucleoprotein complex subunit 2 OS=Homo sapiens OX=9606 GN=NHP2 PE=1 SV=1 8.5 3304.2 - 7.54E+06 - - - -0.4039 - 1.917 0.488 - 317.8 1 2 0 -0.0005 10 0 0 0 2.12E+08 1.68E+08 - - - 4.4617 0.9986 221125_WJC_METTL3_EV_vs_WT_F02.18391.18391.2 0.0519 12-Jul R.GFELTFK[136.11].T "sp|P39656|OST48_HUMAN,tr|U3KQ84|U3KQ84_HUMAN,tr|A0A0C4DGS1|A0A0C4DGS1_HUMAN" 3 848.4524 1.2 17678 18391 2 848.450782 425.2335 Dolichyl-diphosphooligosaccharide--protein glycosyltransferase 48 kDa subunit OS=Homo sapiens OX=9606 GN=DDOST PE=1 SV=4 6 3304.6 - 1.37E+06 - - - -1.854 - 1.441 0.339 - 177.7 1 2 0 -0.0016 7 0 0 0 5.22E+07 4.36E+07 - - - 2.702 0.99 221125_WJC_METTL3_EV_vs_WT_F02.18393.18393.2 0.000115 18-Nov Y.ISPYFINTSK[136.11].G "sp|P10809|CH60_HUMAN,tr|A0A7I2V2X6|A0A7I2V2X6_HUMAN,tr|A0A7I2V599|A0A7I2V599_HUMAN,tr|A0A7I2YQ71|A0A7I2YQ71_HUMAN,tr|E7ESH4|E7ESH4_HUMAN,tr|A0A7I2V5M1|A0A7I2V5M1_HUMAN,tr|A0A7I2V5K3|A0A7I2V5K3_HUMAN,tr|A0A7I2V369|A0A7I2V369_HUMAN" 8 1176.627 0.94 17680 18393 2 1176.626693 589.3208 "60 kDa heat shock protein, mitochondrial OS=Homo sapiens OX=9606 GN=HSPD1 PE=1 SV=2" 8.59 3304.9 - 806069 - - - -0.2822 - 1.987 0.456 - 439.4 1 1 0 -0.0003 10 0 0 0 1.51E+07 1.59E+07 - - - 4.3255 0.999 221125_WJC_METTL3_EV_vs_WT_F02.18398.18398.2 1.99E-06 22-Nov K.TFSYAGFEMQPK[136.11].K sp|Q99832|TCPH_HUMAN 1 1412.6526 0.21 17683 18398 2 1412.648133 707.3336 T-complex protein 1 subunit eta OS=Homo sapiens OX=9606 GN=CCT7 PE=1 SV=2 5.66 3305.6 - 4.53E+06 - - - -3.1536 - 2.203 0.395 - 242.2 1 2 0 -0.0045 12 0 0 0 1.10E+08 5.27E+08 - - - 4.0352 0.9947 221125_WJC_METTL3_EV_vs_WT_F02.18402.18402.2 2.8 12-Jun R.DLIDYVR.Y "sp|Q9Y3C1|NOP16_HUMAN,tr|A0A0C4DGU5|A0A0C4DGU5_HUMAN,tr|D6RIC3|D6RIC3_HUMAN,tr|A0A087X2G6|A0A087X2G6_HUMAN" 4 892.4654 1.01 17687 18402 2 892.464251 447.24 Nucleolar protein 16 OS=Homo sapiens OX=9606 GN=NOP16 PE=1 SV=2 4.21 3305.9 - 1.52E+06 - - - -1.3233 - 1.331 0.184 - 163.6 1 2 0 -0.0012 7 0 0 0 1.66E+07 1.65E+07 - - - 1.3056 1 221125_WJC_METTL3_EV_vs_WT_F02.18403.18403.2 1.14E-05 15/26 R.VLVEATYNPNMPFK.W "sp|Q8IX12|CCAR1_HUMAN,tr|F5H2E6|F5H2E6_HUMAN,tr|A0A0C4DGG8|A0A0C4DGG8_HUMAN,tr|F5H3E1|F5H3E1_HUMAN" 4 1621.8174 2.03 17688 18403 2 1621.82027 811.916 Cell division cycle and apoptosis regulator protein 1 OS=Homo sapiens OX=9606 GN=CCAR1 PE=1 SV=2 5.97 3306 - 1.25E+06 - - - 1.7604 - 2.954 0.639 - 632.7 1 2 0 0.0029 14 0 0 0 1.58E+08 7.81E+07 - - - 6.4779 0.9991 221125_WJC_METTL3_EV_vs_WT_F02.18408.18408.2 0.000327 18-Nov K.IAC[160.03]LDFSLQK[136.11].T "sp|P17987|TCPA_HUMAN,tr|F5GZ03|F5GZ03_HUMAN,tr|F5H282|F5H282_HUMAN,tr|E7EQR6|E7EQR6_HUMAN,tr|E7ERF2|E7ERF2_HUMAN" 5 1201.6256 0.35 17691 18408 2 1201.621642 601.8201 T-complex protein 1 subunit alpha OS=Homo sapiens OX=9606 GN=TCP1 PE=1 SV=1 5.83 3306.6 - 5.02E+06 - - - -3.3313 - 2.141 0.442 - 366.6 1 2 0 -0.004 10 0 0 0 2.21E+08 6.28E+08 - - - 4.4293 0.999 221125_WJC_METTL3_EV_vs_WT_F02.18412.18412.2 0.0376 16-Aug R.VSLLC[160.03]PLGK[136.11].M sp|O75925|PIAS1_HUMAN 1 993.5772 1.19 17695 18412 2 993.576193 497.7959 E3 SUMO-protein ligase PIAS1 OS=Homo sapiens OX=9606 GN=PIAS1 PE=1 SV=2 8.19 3306.9 - 1.61E+06 - - - -1.0518 - 1.778 0.251 - 151.7 1 2 0 -0.001 9 0 0 0 2.03E+07 1.70E+07 - - - 2.5595 0.9977 221125_WJC_METTL3_EV_vs_WT_F02.18415.18415.2 0.36 18-Sep K.TGIPLNVLPK.K sp|Q96GA3|LTV1_HUMAN 1 1050.6437 0.9 17698 18415 2 1050.644156 526.3291 Protein LTV1 homolog OS=Homo sapiens OX=9606 GN=LTV1 PE=1 SV=1 8.41 3307.3 - 1.34E+06 - - - 0.4045 - 1.377 0.244 - 146.3 1 2 0 0.0004 10 0 0 0 2.53E+07 2.81E+07 - - - 1.736 0.9999 221125_WJC_METTL3_EV_vs_WT_F02.18417.18417.3 2.77E-05 13/40 R.TNIIPVIEDAR.H "sp|P22087|FBRL_HUMAN,sp|A6NHQ2|FBLL1_HUMAN,tr|M0R299|M0R299_HUMAN,tr|M0R0P1|M0R0P1_HUMAN,tr|M0QXL5|M0QXL5_HUMAN,tr|M0R2Q4|M0R2Q4_HUMAN" 6 1239.6823 1.04 17700 18417 3 1239.679653 414.2347 rRNA 2'-O-methyltransferase fibrillarin OS=Homo sapiens OX=9606 GN=FBL PE=1 SV=2 4.37 3307.6 - 1.03E+06 - - - -2.1368 - 2.478 0.498 - 268 1 2 0 -0.0026 11 0 0 0 2.12E+07 2.03E+07 - - - 6.6694 1 221125_WJC_METTL3_EV_vs_WT_F02.18418.18418.3 2.46E-07 13/40 R.TNIIPVIEDAR[166.11].H "sp|P22087|FBRL_HUMAN,sp|A6NHQ2|FBLL1_HUMAN,tr|M0R299|M0R299_HUMAN,tr|M0R0P1|M0R0P1_HUMAN,tr|M0QXL5|M0QXL5_HUMAN,tr|M0R2Q4|M0R2Q4_HUMAN" 6 1249.6906 1.04 17701 18418 3 1249.689296 417.5708 rRNA 2'-O-methyltransferase fibrillarin OS=Homo sapiens OX=9606 GN=FBL PE=1 SV=2 4.37 3307.7 - 1.00E+06 - - - -1.0211 - 2.508 0.533 - 341.6 1 2 0 -0.0013 11 0 0 0 2.09E+07 2.02E+07 - - - 7.0942 0.9995 221125_WJC_METTL3_EV_vs_WT_F02.18419.18419.2 0.00221 22-Dec K.VFLGNGISELSR.K sp|Q8TEA1|NSUN6_HUMAN 1 1290.6932 0.73 17702 18419 2 1290.69141 646.3539 tRNA (cytosine(72)-C(5))-methyltransferase NSUN6 OS=Homo sapiens OX=9606 GN=NSUN6 PE=1 SV=1 5.97 3307.9 - 996823 - - - -1.3876 - 2.113 0.34 - 462.8 1 2 0 -0.0018 12 0 0 0 1.39E+07 1.89E+07 - - - 3.5201 0.9878 221125_WJC_METTL3_EV_vs_WT_F02.18423.18423.2 0.000309 20-Dec Q.WGTLTDC[160.03]VVMR[166.11].D "sp|Q32P51|RA1L2_HUMAN,sp|P51991|ROA3_HUMAN,sp|P09651|ROA1_HUMAN,tr|A0A7I2V5D8|A0A7I2V5D8_HUMAN,tr|F8W646|F8W646_HUMAN,tr|A0A7I2V2R3|A0A7I2V2R3_HUMAN,tr|F8VZ49|F8VZ49_HUMAN,tr|A0A7I2V3R8|A0A7I2V3R8_HUMAN,tr|F8W6I7|F8W6I7_HUMAN,tr|A0A7I2V2L6|A0A7I2V2L6_HUMAN,tr|A0A7I2V4J6|A0A7I2V4J6_HUMAN,tr|A0A7I2V3W0|A0A7I2V3W0_HUMAN,tr|A0A7I2V4G0|A0A7I2V4G0_HUMAN,tr|A0A7I2V402|A0A7I2V402_HUMAN" 14 1346.635 1.07 17704 18423 2 1346.633108 674.3248 Heterogeneous nuclear ribonucleoprotein A1-like 2 OS=Homo sapiens OX=9606 GN=HNRNPA1L2 PE=2 SV=2 5.83 3308.3 - 3.41E+06 - - - -1.4406 - 2.189 0.472 - 367.5 1 1 0 -0.0019 11 0 0 0 5.64E+07 5.28E+07 - - - 4.646 0.9998 221125_WJC_METTL3_EV_vs_WT_F02.18424.18424.2 0.00121 18-Nov K.IAC[160.03]LDFSLQK.T "sp|P17987|TCPA_HUMAN,tr|F5GZ03|F5GZ03_HUMAN,tr|F5H282|F5H282_HUMAN,tr|E7EQR6|E7EQR6_HUMAN,tr|E7ERF2|E7ERF2_HUMAN" 5 1193.6114 0.35 17705 18424 2 1193.610135 597.813 T-complex protein 1 subunit alpha OS=Homo sapiens OX=9606 GN=TCP1 PE=1 SV=1 5.83 3308.4 - 4.46E+06 - - - -1.0975 - 2.082 0.431 - 373.9 1 2 0 -0.0013 10 0 0 0 2.21E+08 6.27E+08 - - - 4.2709 0.9992 221125_WJC_METTL3_EV_vs_WT_F02.18425.18425.2 0.00186 14-Aug K.VFLENVIR.D sp|P62805|H4_HUMAN 1 988.5706 1.23 17706 18425 2 988.569145 495.2926 Histone H4 OS=Homo sapiens OX=9606 GN=H4C1 PE=1 SV=2 5.97 3308.4 - 3.34E+06 - - - -1.4374 - 1.74 0.311 - 272.3 1 2 0 -0.0014 8 0 0 0 1.35E+08 1.10E+08 - - - 3.0081 0.9908 221125_WJC_METTL3_EV_vs_WT_F02.18426.18426.2 0.828 12-Jun K.DLQNFLK.K sp|P06702|S10A9_HUMAN 1 876.4705 2989.32 17707 18426 2 876.46929 439.2425 Protein S100-A9 OS=Homo sapiens OX=9606 GN=S100A9 PE=1 SV=1 5.84 3308.5 - 2.90E+06 - - - -1.4011 - 1.179 0.186 - 109.1 1 2 0 -0.0012 7 0 0 0 1.97E+09 6.58E+05 - - - 0.9362 0.9998 221125_WJC_METTL3_EV_vs_WT_F02.18427.18427.2 5.60E-07 20-Nov K.AC[160.03]FGTFLPEEK.L sp|Q9NRP4|SDHF3_HUMAN 1 1297.6013 0.79 17708 18427 2 1297.600016 649.8079 "Succinate dehydrogenase assembly factor 3, mitochondrial OS=Homo sapiens OX=9606 GN=SDHAF3 PE=1 SV=1" 4.53 3308.6 - 2.18E+06 - - - -0.9695 - 1.978 0.511 - 416.9 1 2 0 -0.0013 11 0 0 0 4.07E+07 5.16E+07 - - - 4.6601 0.9994 221125_WJC_METTL3_EV_vs_WT_F02.18428.18428.2 0.00132 13/22 R.ELLLTGPGLEER.V sp|Q8N1G4|LRC47_HUMAN 1 1325.7191 0.67 17709 18428 2 1325.716275 663.8668 Leucine-rich repeat-containing protein 47 OS=Homo sapiens OX=9606 GN=LRRC47 PE=1 SV=1 4.25 3308.7 - 2.08E+06 - - - -2.1166 - 2.2 0.368 - 680.4 1 2 0 -0.0028 12 0 0 0 6.21E+07 9.27E+07 - - - 3.8327 1 221125_WJC_METTL3_EV_vs_WT_F02.18431.18431.3 5.70E-06 13/40 K.RPLFLAPDFDR.W "sp|Q9P035|HACD3_HUMAN,tr|H3BPZ1|H3BPZ1_HUMAN,tr|H3BS72|H3BS72_HUMAN" 3 1345.7143 1.1 17712 18431 3 1345.712631 449.5787 Very-long-chain (3R)-3-hydroxyacyl-CoA dehydratase 3 OS=Homo sapiens OX=9606 GN=HACD3 PE=1 SV=2 5.96 3309.1 - 1.35E+06 - - - -1.2179 - 2.464 0.534 - 430.8 1 2 0 -0.0016 11 0 0 0 5.88E+07 5.33E+07 - - - 7.0549 0.9997 221125_WJC_METTL3_EV_vs_WT_F02.18432.18432.2 0.000909 13/20 K.SILFVPTSAPR.G "sp|P14625|ENPL_HUMAN,tr|A0A7P0T917|A0A7P0T917_HUMAN,tr|A0A7P0T823|A0A7P0T823_HUMAN,tr|A0A7P0TAE1|A0A7P0TAE1_HUMAN,tr|H0YIV0|H0YIV0_HUMAN,tr|A0A7P0TAY2|A0A7P0TAY2_HUMAN,tr|A0A087WT78|A0A087WT78_HUMAN,tr|A0A7P0TBC2|A0A7P0TBC2_HUMAN,tr|A0A7P0TAT8|A0A7P0TAT8_HUMAN" 9 1186.671 11.9 17713 18432 2 1186.669635 594.3428 Endoplasmin OS=Homo sapiens OX=9606 GN=HSP90B1 PE=1 SV=1 9.47 3309.2 - 1.17E+06 - - - -1.1579 - 2.372 0.332 - 619.3 1 2 0 -0.0014 11 0 0 0 8.52E+07 7.16E+06 - - - 3.8293 0.991 221125_WJC_METTL3_EV_vs_WT_F02.18433.18433.2 3.84E-06 Oct-32 K.VVGSAVGSGSITSNIVA.S "sp|Q9Y5A9|YTHD2_HUMAN,tr|S4R3V3|S4R3V3_HUMAN" 2 1516.8097 - 17714 18433 2 1516.808773 759.4121 YTH domain-containing family protein 2 OS=Homo sapiens OX=9606 GN=YTHDF2 PE=1 SV=2 5.49 3309.4 - 1.09E+06 - - - -0.6026 - 2.089 0.502 - 229.7 1 1 0 -0.0009 17 0 0 0 - - - - - 4.5597 0.9999 221125_WJC_METTL3_EV_vs_WT_F02.18434.18434.2 6.68E-08 18/30 K.LGLPPLTPEQQEALQK[136.11].A "sp|Q9UHX1|PUF60_HUMAN,tr|A0A0J9YYL3|A0A0J9YYL3_HUMAN,tr|A0A0J9YWM1|A0A0J9YWM1_HUMAN,tr|H0YEM1|H0YEM1_HUMAN,tr|E9PMU7|E9PMU7_HUMAN,tr|E9PN18|E9PN18_HUMAN,tr|E9PL19|E9PL19_HUMAN,tr|A0A0J9YVR6|A0A0J9YVR6_HUMAN,tr|A0A0J9YXX5|A0A0J9YXX5_HUMAN,tr|A0A0J9YXJ8|A0A0J9YXJ8_HUMAN,tr|E9PQ56|E9PQ56_HUMAN,tr|A0A0J9YVP6|A0A0J9YVP6_HUMAN" 12 1768.9814 1.37 17715 18434 2 1768.980786 885.498 Poly(U)-binding-splicing factor PUF60 OS=Homo sapiens OX=9606 GN=PUF60 PE=1 SV=1 4.53 3309.5 - 683706 - - - -0.3754 - 2.859 0.55 - 603.5 1 2 0 -0.0007 16 0 0 0 5.74E+07 4.18E+07 - - - 5.6857 0.9998 221125_WJC_METTL3_EV_vs_WT_F02.18438.18438.2 0.00028 22-Nov K.YNILGTNTIMDK.M "sp|Q00839|HNRPU_HUMAN,tr|A0A1W2PQL0|A0A1W2PQL0_HUMAN,tr|A0A1W2PPL4|A0A1W2PPL4_HUMAN,tr|A0A1W2PQ74|A0A1W2PQ74_HUMAN,tr|Q5RI18|Q5RI18_HUMAN,tr|A0A1W2PP35|A0A1W2PP35_HUMAN,tr|A0A1W2PPS1|A0A1W2PPS1_HUMAN,tr|A0A1W2PRZ7|A0A1W2PRZ7_HUMAN,tr|A0A1W2PPH7|A0A1W2PPH7_HUMAN,tr|A0A1W2PQD4|A0A1W2PQD4_HUMAN,tr|A0A1W2PP34|A0A1W2PP34_HUMAN,tr|A0A1X7SBS1|A0A1X7SBS1_HUMAN" 12 1381.6912 0.57 17718 18438 2 1381.691936 691.8529 Heterogeneous nuclear ribonucleoprotein U OS=Homo sapiens OX=9606 GN=HNRNPU PE=1 SV=6 5.83 3309.8 - 4.86E+06 - - - 0.5674 - 2.383 0.409 - 312.9 1 2 0 0.0008 12 0 0 0 4.34E+09 7.60E+09 - - - 4.3464 0.9999 221125_WJC_METTL3_EV_vs_WT_F02.18439.18439.2 8.45E-06 13/22 K.LIEAVDNMLSNK.L sp|Q9H223|EHD4_HUMAN 1 1345.6912 2.45 17719 18439 2 1345.690508 673.8529 EH domain-containing protein 4 OS=Homo sapiens OX=9606 GN=EHD4 PE=1 SV=1 4.37 3309.9 - 4.44E+06 - - - -0.4786 - 2.519 0.574 - 460.6 1 2 0 -0.0006 12 0 0 0 9.61E+07 3.92E+07 - - - 5.7112 1 221125_WJC_METTL3_EV_vs_WT_F02.18441.18441.2 8.91E-10 15/26 R.VLVEATYNPNMPFK[136.11].W "sp|Q8IX12|CCAR1_HUMAN,tr|F5H2E6|F5H2E6_HUMAN,tr|A0A0C4DGG8|A0A0C4DGG8_HUMAN,tr|F5H3E1|F5H3E1_HUMAN" 4 1629.8316 4.9 17721 18441 2 1629.831251 815.9231 Cell division cycle and apoptosis regulator protein 1 OS=Homo sapiens OX=9606 GN=CCAR1 PE=1 SV=2 5.97 3310.1 - 2.37E+06 - - - -0.2233 - 3.012 0.648 - 708.2 1 2 0 -0.0004 14 0 0 0 1.35E+08 2.75E+07 - - - 6.5939 0.9999 221125_WJC_METTL3_EV_vs_WT_F02.18442.18442.3 0.00033 Nov-48 R.MVIITGPPEAQFK.A "sp|Q9NZI8|IF2B1_HUMAN,sp|O00425|IF2B3_HUMAN,sp|Q9Y6M1|IF2B2_HUMAN,tr|F8W930|F8W930_HUMAN" 4 1429.7639 1.77 17722 18442 3 1429.762687 477.5953 Insulin-like growth factor 2 mRNA-binding protein 1 OS=Homo sapiens OX=9606 GN=IGF2BP1 PE=1 SV=2 5.75 3310.2 - 1.94E+06 - - - -0.8645 - 2.365 0.381 - 133.9 1 2 0 -0.0012 13 0 0 0 1.41E+08 7.95E+07 - - - 5.1213 0.9998 221125_WJC_METTL3_EV_vs_WT_F02.18443.18443.2 6.12E-08 18/30 K.LGLPPLTPEQQEALQK.A "sp|Q9UHX1|PUF60_HUMAN,tr|A0A0J9YYL3|A0A0J9YYL3_HUMAN,tr|A0A0J9YWM1|A0A0J9YWM1_HUMAN,tr|H0YEM1|H0YEM1_HUMAN,tr|E9PMU7|E9PMU7_HUMAN,tr|E9PN18|E9PN18_HUMAN,tr|E9PL19|E9PL19_HUMAN,tr|A0A0J9YVR6|A0A0J9YVR6_HUMAN,tr|A0A0J9YXX5|A0A0J9YXX5_HUMAN,tr|A0A0J9YXJ8|A0A0J9YXJ8_HUMAN,tr|E9PQ56|E9PQ56_HUMAN,tr|A0A0J9YVP6|A0A0J9YVP6_HUMAN" 12 1760.9672 1.37 17723 18443 2 1760.970153 881.4909 Poly(U)-binding-splicing factor PUF60 OS=Homo sapiens OX=9606 GN=PUF60 PE=1 SV=1 4.53 3310.3 - 1.32E+06 - - - 1.6485 - 2.927 0.511 - 564 1 2 0 0.0029 16 0 0 0 5.74E+07 4.18E+07 - - - 5.4548 0.9798 221125_WJC_METTL3_EV_vs_WT_F02.18444.18444.3 0.0612 16/60 K.LGLPPLTPEQQEALQK.A "sp|Q9UHX1|PUF60_HUMAN,tr|A0A0J9YYL3|A0A0J9YYL3_HUMAN,tr|A0A0J9YWM1|A0A0J9YWM1_HUMAN,tr|H0YEM1|H0YEM1_HUMAN,tr|E9PMU7|E9PMU7_HUMAN,tr|E9PN18|E9PN18_HUMAN,tr|E9PL19|E9PL19_HUMAN,tr|A0A0J9YVR6|A0A0J9YVR6_HUMAN,tr|A0A0J9YXX5|A0A0J9YXX5_HUMAN,tr|A0A0J9YXJ8|A0A0J9YXJ8_HUMAN,tr|E9PQ56|E9PQ56_HUMAN,tr|A0A0J9YVP6|A0A0J9YVP6_HUMAN" 12 1760.9672 1.34 17724 18444 3 1760.967513 587.9964 Poly(U)-binding-splicing factor PUF60 OS=Homo sapiens OX=9606 GN=PUF60 PE=1 SV=1 4.53 3310.4 - 821428 - - - 0.1493 - 1.762 0.125 - 172.2 1 2 0 0.0003 16 0 0 0 2.47E+07 1.85E+07 - - - 1.387 1 221125_WJC_METTL3_EV_vs_WT_F02.18445.18445.2 3.31E-10 17/30 K.LASAFTEEQAVLYNQR[166.11].V sp|Q9UHB9|SRP68_HUMAN 1 1848.9245 0.59 17725 18445 2 1848.920231 925.4695 Signal recognition particle subunit SRP68 OS=Homo sapiens OX=9606 GN=SRP68 PE=1 SV=2 4.53 3310.6 - 812425 - - - -2.3343 - 3.42 0.646 - 1401.5 1 2 0 -0.0043 16 0 0 0 5.39E+06 9.17E+06 - - - 6.8341 0.9999 221125_WJC_METTL3_EV_vs_WT_F02.18450.18450.3 6.57E-05 13/52 R.VLVEATYNPNMPFK.W "sp|Q8IX12|CCAR1_HUMAN,tr|F5H2E6|F5H2E6_HUMAN,tr|A0A0C4DGG8|A0A0C4DGG8_HUMAN,tr|F5H3E1|F5H3E1_HUMAN" 4 1621.8174 0.43 17728 18450 3 1621.818528 541.6131 Cell division cycle and apoptosis regulator protein 1 OS=Homo sapiens OX=9606 GN=CCAR1 PE=1 SV=2 5.97 3311.2 - 1.44E+06 - - - 0.6863 - 2.333 0.437 - 211.3 1 2 0 0.0011 14 0 0 0 1.62E+07 3.73E+07 - - - 5.6632 0.9997 221125_WJC_METTL3_EV_vs_WT_F02.18451.18451.2 0.00056 22-Oct R.GGGVGGFLPAMK[136.11].Q sp|Q9Y3I0|RTCB_HUMAN 1 1097.5783 1.48 17729 18451 2 1097.578446 549.7964 RNA-splicing ligase RtcB homolog OS=Homo sapiens OX=9606 GN=RTCB PE=1 SV=1 8.75 3311.3 - 2.41E+06 - - - 0.1321 - 1.667 0.415 - 185.9 1 2 0 0.0001 12 0 0 0 1.34E+08 9.05E+07 - - - 3.4507 0.9971 221125_WJC_METTL3_EV_vs_WT_F02.18452.18452.2 3.21E-06 14/24 R.NMLGTLAGANSLR.N sp|Q13835|PKP1_HUMAN 1 1316.6871 3.12 17730 18452 2 1316.679956 659.3508 Plakophilin-1 OS=Homo sapiens OX=9606 GN=PKP1 PE=1 SV=2 9.75 3311.4 - 1.42E+06 - - - -5.4022 - 2.464 0.494 - 769.2 1 2 0 -0.0071 13 0 0 0 3.67E+07 1.18E+07 - - - 5.0019 0.9996 221125_WJC_METTL3_EV_vs_WT_F02.18455.18455.2 0.333 20-Nov R.TNIIPVIEDAR.H "sp|P22087|FBRL_HUMAN,sp|A6NHQ2|FBLL1_HUMAN,tr|M0R299|M0R299_HUMAN,tr|M0R0P1|M0R0P1_HUMAN,tr|M0QXL5|M0QXL5_HUMAN,tr|M0R2Q4|M0R2Q4_HUMAN" 6 1239.6823 4.02 17732 18455 2 1239.682267 620.8484 rRNA 2'-O-methyltransferase fibrillarin OS=Homo sapiens OX=9606 GN=FBL PE=1 SV=2 4.37 3311.8 - 1.57E+07 - - - -0.0282 - 2.519 0.23 - 393.6 1 2 0 0 11 0 0 0 9.58E+08 2.38E+08 - - - 3.239 0.9999 221125_WJC_METTL3_EV_vs_WT_F02.18458.18458.2 0.00827 13/24 R.ENLLEEQGSIALR.Q "sp|Q13813|SPTN1_HUMAN,tr|A0A0D9SF54|A0A0D9SF54_HUMAN,tr|A0A0D9SGF6|A0A0D9SGF6_HUMAN" 3 1470.7678 1.09 17734 18458 2 1470.766438 736.3912 "Spectrin alpha chain, non-erythrocytic 1 OS=Homo sapiens OX=9606 GN=SPTAN1 PE=1 SV=3" 4.25 3312.1 - 1.85E+06 - - - -0.941 - 2.782 0.429 - 668.5 1 2 0 -0.0014 13 0 0 0 3.17E+07 2.91E+07 - - - 4.8352 0.9296 221125_WJC_METTL3_EV_vs_WT_F02.18459.18459.2 0.775 13/22 M.SVEQEILVTGIK.V "sp|P06576|ATPB_HUMAN,tr|F8W079|F8W079_HUMAN,tr|H0YH81|H0YH81_HUMAN" 3 1314.7395 0.4 17735 18459 2 1314.738503 658.377 "ATP synthase subunit beta, mitochondrial OS=Homo sapiens OX=9606 GN=ATP5F1B PE=1 SV=3" 4.53 3312.3 - 1.37E+06 - - - -0.7446 - 2.022 0.183 - 478.3 1 1 0 -0.001 12 0 0 0 1.05E+07 2.64E+07 - - - 2.2449 0.9993 221125_WJC_METTL3_EV_vs_WT_F02.18461.18461.2 0.000194 26-Dec R.LEITPVVC[160.03]NVEQVR[166.11].L sp|Q9UI36|DACH1_HUMAN 1 1664.8795 3.13 17737 18461 2 1664.874118 833.447 Dachshund homolog 1 OS=Homo sapiens OX=9606 GN=DACH1 PE=1 SV=4 4.53 3312.5 - 379985 - - - -3.2399 - 2.322 0.499 - 349.8 1 2 0 -0.0054 14 0 0 0 2.74E+07 8.77E+06 - - - 4.839 0.9993 221125_WJC_METTL3_EV_vs_WT_F02.18463.18463.2 0.133 14-Aug R.ILELDQFK[136.11].G "sp|P12956|XRCC6_HUMAN,tr|B1AHC9|B1AHC9_HUMAN" 2 1012.5684 0.66 17738 18463 2 1012.567646 507.2915 X-ray repair cross-complementing protein 6 OS=Homo sapiens OX=9606 GN=XRCC6 PE=1 SV=2 4.37 3312.7 - 4.69E+06 - - - -0.7911 - 1.703 0.293 - 151.2 1 2 0 -0.0008 8 0 0 0 8.70E+07 1.31E+08 - - - 2.8105 1 221125_WJC_METTL3_EV_vs_WT_F02.18465.18465.3 1.60E-06 14/52 R.LGESQTLLAAAVER.E "sp|P82094|TMF1_HUMAN,tr|A0A2R8Y7M0|A0A2R8Y7M0_HUMAN" 2 1456.7886 1.47 17739 18465 3 1456.789079 486.6035 TATA element modulatory factor OS=Homo sapiens OX=9606 GN=TMF1 PE=1 SV=2 4.53 3312.9 - 1.42E+06 - - - 0.3576 - 2.605 0.459 - 326.9 1 2 0 0.0005 14 0 0 0 7.40E+07 5.04E+07 - - - 6.2017 0.9999 221125_WJC_METTL3_EV_vs_WT_F02.18466.18466.3 0.000197 14/52 R.LGESQTLLAAAVER[166.11].E "sp|P82094|TMF1_HUMAN,tr|A0A2R8Y7M0|A0A2R8Y7M0_HUMAN" 2 1466.7968 1.54 17740 18466 3 1466.797019 489.9396 TATA element modulatory factor OS=Homo sapiens OX=9606 GN=TMF1 PE=1 SV=2 4.53 3313.1 - 1.50E+06 - - - 0.1302 - 2.593 0.367 - 273.6 1 2 0 0.0002 14 0 0 0 7.37E+07 4.79E+07 - - - 5.1638 1 221125_WJC_METTL3_EV_vs_WT_F02.18467.18467.2 2.57E-05 16/26 R.LGESQTLLAAAVER[166.11].E "sp|P82094|TMF1_HUMAN,tr|A0A2R8Y7M0|A0A2R8Y7M0_HUMAN" 2 1466.7968 1.54 17741 18467 2 1466.793966 734.4057 TATA element modulatory factor OS=Homo sapiens OX=9606 GN=TMF1 PE=1 SV=2 4.53 3313.1 - 2.85E+06 - - - -1.9512 - 3.078 0.526 - 1066.7 1 2 0 -0.0029 14 0 0 0 1.89E+08 1.22E+08 - - - 5.7465 0.9975 221125_WJC_METTL3_EV_vs_WT_F02.18468.18468.2 1.16 16-Nov R.TLLIDELNK[136.11].L "sp|Q9NQW6|ANLN_HUMAN,tr|H7C1K5|H7C1K5_HUMAN" 2 1065.6161 0.29 17742 18468 2 1065.617223 533.8153 Anillin OS=Homo sapiens OX=9606 GN=ANLN PE=1 SV=2 4.37 3313.2 - 1.16E+06 - - - 1.0295 - 1.69 0.175 - 347.3 1 2 0 0.0011 9 0 0 0 3.05E+06 1.06E+07 - - - 1.8513 0.9999 221125_WJC_METTL3_EV_vs_WT_F02.18469.18469.2 1.26E-06 14/24 K.LLTSYGFIQC[160.03]SER[166.11].Q "sp|O75534|CSDE1_HUMAN,tr|E9PLD4|E9PLD4_HUMAN,tr|E9PKN4|E9PKN4_HUMAN" 3 1582.7689 0.66 17743 18469 2 1582.768361 792.3917 Cold shock domain-containing protein E1 OS=Homo sapiens OX=9606 GN=CSDE1 PE=1 SV=2 5.99 3313.4 - 1.06E+06 - - - -0.3399 - 2.752 0.404 - 760.8 1 2 0 -0.0005 13 0 0 0 4.09E+07 6.23E+07 - - - 4.6229 0.9958 221125_WJC_METTL3_EV_vs_WT_F02.18472.18472.2 0.103 18-Nov K.AIPQLQGYLR[166.11].S sp|Q02878|RL6_HUMAN 1 1167.664 1.32 17745 18472 2 1167.664958 584.8393 60S ribosomal protein L6 OS=Homo sapiens OX=9606 GN=RPL6 PE=1 SV=3 8.79 3313.7 - 3.12E+06 - - - 0.8521 - 1.542 0.153 - 502.1 1 2 0 0.001 10 0 0 0 2.28E+08 1.72E+08 - - - 1.3796 0.9981 221125_WJC_METTL3_EV_vs_WT_F02.18473.18473.2 0.0901 12-Jun R.GFELTFK.T "sp|P39656|OST48_HUMAN,tr|U3KQ84|U3KQ84_HUMAN,tr|A0A0C4DGS1|A0A0C4DGS1_HUMAN" 3 840.4382 1.2 17746 18473 2 840.43641 421.2264 Dolichyl-diphosphooligosaccharide--protein glycosyltransferase 48 kDa subunit OS=Homo sapiens OX=9606 GN=DDOST PE=1 SV=4 6 3313.9 - 1.36E+06 - - - -2.0763 - 1.349 0.345 - 117.6 1 2 0 -0.0017 7 0 0 0 5.22E+07 4.36E+07 - - - 2.5372 0.9998 221125_WJC_METTL3_EV_vs_WT_F02.18474.18474.2 0.000303 22-Dec R.ELLLTGPGLEER[166.11].V sp|Q8N1G4|LRC47_HUMAN 1 1335.7274 0.66 17747 18474 2 1335.727908 668.871 Leucine-rich repeat-containing protein 47 OS=Homo sapiens OX=9606 GN=LRRC47 PE=1 SV=1 4.25 3313.9 - 3.59E+06 - - - 0.417 - 2.285 0.411 - 612.8 1 2 0 0.0006 12 0 0 0 6.15E+07 9.27E+07 - - - 4.2508 0.9999 221125_WJC_METTL3_EV_vs_WT_F02.18475.18475.2 0.000157 18-Nov R.FVNVVPTFGK.K "sp|P62861|RS30_HUMAN,tr|E9PR30|E9PR30_HUMAN" 2 1106.6124 0.4 17748 18475 2 1106.611996 554.3135 40S ribosomal protein S30 OS=Homo sapiens OX=9606 GN=FAU PE=1 SV=1 8.75 3314 - 2.60E+06 - - - -0.3931 - 2.183 0.497 - 370.7 1 2 0 -0.0004 10 0 0 0 1.55E+08 3.88E+08 - - - 4.8909 0.9721 221125_WJC_METTL3_EV_vs_WT_F02.18476.18476.3 0.000532 Dec-48 H.TLTLVDTGIGMTK[136.11].A "sp|Q58FF8|H90B2_HUMAN,sp|P08238|HS90B_HUMAN,sp|Q58FG1|HS904_HUMAN,sp|P07900|HS90A_HUMAN,sp|Q14568|HS902_HUMAN,tr|G3V2J8|G3V2J8_HUMAN" 6 1356.7414 0.69 17749 18476 3 1356.738692 453.2544 Putative heat shock protein HSP 90-beta 2 OS=Homo sapiens OX=9606 GN=HSP90AB2P PE=1 SV=2 5.5 3314.1 - 969348 - - - -1.9982 - 1.934 0.402 - 185.5 1 1 0 -0.0027 13 0 0 0 1.09E+07 1.58E+07 - - - 4.8095 1 221125_WJC_METTL3_EV_vs_WT_F02.18477.18477.2 1.98E-12 16/28 R.FVEGVC[160.03]PFC[160.03]GYEEAR[166.11].G "sp|P56192|SYMC_HUMAN,tr|H0YIC2|H0YIC2_HUMAN" 2 1828.7788 1.13 17750 18477 2 1828.777504 915.3967 "Methionine--tRNA ligase, cytoplasmic OS=Homo sapiens OX=9606 GN=MARS1 PE=1 SV=2" 4.25 3314.2 - 923478 - - - -0.7152 - 3.027 0.67 - 752 1 2 0 -0.0013 15 0 0 0 1.50E+07 1.32E+07 - - - 6.7122 0.9966 221125_WJC_METTL3_EV_vs_WT_F02.18478.18478.3 0.866 Aug-44 K.YNILGTNTIMDK.M "sp|Q00839|HNRPU_HUMAN,tr|A0A1W2PQL0|A0A1W2PQL0_HUMAN,tr|A0A1W2PPL4|A0A1W2PPL4_HUMAN,tr|A0A1W2PQ74|A0A1W2PQ74_HUMAN,tr|Q5RI18|Q5RI18_HUMAN,tr|A0A1W2PP35|A0A1W2PP35_HUMAN,tr|A0A1W2PPS1|A0A1W2PPS1_HUMAN,tr|A0A1W2PRZ7|A0A1W2PRZ7_HUMAN,tr|A0A1W2PPH7|A0A1W2PPH7_HUMAN,tr|A0A1W2PQD4|A0A1W2PQD4_HUMAN,tr|A0A1W2PP34|A0A1W2PP34_HUMAN,tr|A0A1X7SBS1|A0A1X7SBS1_HUMAN" 12 1381.6912 0.38 17751 18478 3 1381.689752 461.571 Heterogeneous nuclear ribonucleoprotein U OS=Homo sapiens OX=9606 GN=HNRNPU PE=1 SV=6 5.83 3314.3 - 906127 - - - -1.0133 - 1.558 0.243 - 84.7 1 2 0 -0.0014 12 0 0 0 3.56E+07 9.24E+07 - - - 2.4779 0.9996 221125_WJC_METTL3_EV_vs_WT_F02.18479.18479.2 0.00523 22-Dec R.VLIGNVQPGILR.F "sp|Q5VT06|CE350_HUMAN,tr|H0Y7F7|H0Y7F7_HUMAN" 2 1277.782 2.65 17752 18479 2 1277.784383 639.8983 Centrosome-associated protein 350 OS=Homo sapiens OX=9606 GN=CEP350 PE=1 SV=1 9.72 3314.5 - 746103 - - - 1.8994 - 2.286 0.4 - 577.2 1 2 0 0.0024 12 0 0 0 1.07E+07 4.05E+06 - - - 4.1701 1 221125_WJC_METTL3_EV_vs_WT_F02.18481.18481.2 8.15E-12 16/28 R.FVEGVC[160.03]PFC[160.03]GYEEAR.G "sp|P56192|SYMC_HUMAN,tr|H0YIC2|H0YIC2_HUMAN" 2 1818.7705 1.13 17754 18481 2 1818.768279 910.3925 "Methionine--tRNA ligase, cytoplasmic OS=Homo sapiens OX=9606 GN=MARS1 PE=1 SV=2" 4.25 3314.7 - 596731 - - - -1.2442 - 3.039 0.761 - 706.2 1 2 0 -0.0023 15 0 0 0 1.50E+07 1.32E+07 - - - 7.3938 0.9982 221125_WJC_METTL3_EV_vs_WT_F02.18482.18482.2 0.0849 22-Aug R.VLIGNVQPGILR[166.11].F "sp|Q5VT06|CE350_HUMAN,tr|H0Y7F7|H0Y7F7_HUMAN" 2 1287.7902 2.65 17755 18482 2 1287.79208 644.9024 Centrosome-associated protein 350 OS=Homo sapiens OX=9606 GN=CEP350 PE=1 SV=1 9.72 3314.9 - 520033 - - - 1.4397 - 1.312 0.344 - 131.6 1 2 0 0.0019 12 0 0 0 1.07E+07 4.05E+06 - - - 2.2957 0.9996 221125_WJC_METTL3_EV_vs_WT_F02.18486.18486.2 0.00637 14-Aug K.VFLENVIR[166.11].D sp|P62805|H4_HUMAN 1 998.5788 1.27 17757 18486 2 998.578521 500.2967 Histone H4 OS=Homo sapiens OX=9606 GN=H4C1 PE=1 SV=2 5.97 3315.4 - 5.13E+06 - - - -0.3154 - 1.731 0.356 - 274.5 1 2 0 -0.0003 8 0 0 0 1.41E+08 1.11E+08 - - - 3.3252 0.9999 221125_WJC_METTL3_EV_vs_WT_F02.18488.18488.3 0.00101 Nov-48 R.MVIITGPPEAQFK[136.11].A "sp|Q9NZI8|IF2B1_HUMAN,sp|O00425|IF2B3_HUMAN,sp|Q9Y6M1|IF2B2_HUMAN,tr|F8W930|F8W930_HUMAN" 4 1437.7781 1.75 17759 18488 3 1437.777297 480.2667 Insulin-like growth factor 2 mRNA-binding protein 1 OS=Homo sapiens OX=9606 GN=IGF2BP1 PE=1 SV=2 5.75 3315.5 - 4.34E+06 - - - -0.5745 - 2.228 0.452 - 136.7 1 2 0 -0.0008 13 0 0 0 1.39E+08 7.92E+07 - - - 5.7512 0.9998 221125_WJC_METTL3_EV_vs_WT_F02.18489.18489.2 0.0181 14-Oct R.VDEIIWVK[136.11].T sp|Q86U44|MTA70_HUMAN 1 1008.5735 0 17760 18489 2 1008.572702 505.294 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 4.37 3315.5 - 3.68E+06 - - - -0.8239 - 2.245 0.364 - 351.8 1 2 0 -0.0008 8 0 0 0 3.94E+05 1.10E+08 - - - 4.1683 1 221125_WJC_METTL3_EV_vs_WT_F02.18491.18491.3 4.01E-06 13/40 K.R[166.11]PLFLAPDFDR[166.11].W "sp|Q9P035|HACD3_HUMAN,tr|H3BPZ1|H3BPZ1_HUMAN,tr|H3BS72|H3BS72_HUMAN" 3 1365.7308 1.09 17762 18491 3 1365.727355 456.2509 Very-long-chain (3R)-3-hydroxyacyl-CoA dehydratase 3 OS=Homo sapiens OX=9606 GN=HACD3 PE=1 SV=2 5.96 3315.7 - 1.36E+06 - - - -2.5298 - 2.628 0.536 - 456.3 1 2 0 -0.0035 11 0 0 0 5.92E+07 5.44E+07 - - - 7.2598 0.9999 221125_WJC_METTL3_EV_vs_WT_F02.18492.18492.2 2.44E-07 14/26 R.LEITPVVC[160.03]NVEQVR.L sp|Q9UI36|DACH1_HUMAN 1 1654.8712 3.13 17763 18492 2 1654.871824 828.4429 Dachshund homolog 1 OS=Homo sapiens OX=9606 GN=DACH1 PE=1 SV=4 4.53 3315.9 - 1.35E+06 - - - 0.3517 - 2.605 0.547 - 534.1 1 2 0 0.0006 14 0 0 0 2.74E+07 8.77E+06 - - - 5.4836 0.9998 221125_WJC_METTL3_EV_vs_WT_F02.18493.18493.2 2.59E-10 24-Nov K.LLTSYGFIQC[160.03]SER.Q "sp|O75534|CSDE1_HUMAN,tr|E9PLD4|E9PLD4_HUMAN,tr|E9PKN4|E9PKN4_HUMAN" 3 1572.7606 0.66 17764 18493 2 1572.761563 787.3876 Cold shock domain-containing protein E1 OS=Homo sapiens OX=9606 GN=CSDE1 PE=1 SV=2 5.99 3316 - 1.19E+06 - - - 0.5939 - 2.482 0.37 - 445.3 1 2 0 0.0009 13 0 0 0 4.09E+07 6.23E+07 - - - 4.1067 1 221125_WJC_METTL3_EV_vs_WT_F02.18497.18497.2 4.69E-07 14/26 R.LGESQTLLAAAVER.E "sp|P82094|TMF1_HUMAN,tr|A0A2R8Y7M0|A0A2R8Y7M0_HUMAN" 2 1456.7886 1.54 17766 18497 2 1456.785476 729.4016 TATA element modulatory factor OS=Homo sapiens OX=9606 GN=TMF1 PE=1 SV=2 4.53 3316.5 - 1.05E+07 - - - -2.1156 - 3.008 0.54 - 683.3 1 2 0 -0.0031 14 0 0 0 1.89E+08 1.22E+08 - - - 5.7921 0.9996 221125_WJC_METTL3_EV_vs_WT_F02.18498.18498.3 0.000172 Oct-56 K.VMLMASPSMEDLYHK.S "sp|Q8IX12|CCAR1_HUMAN,tr|F5H2E6|F5H2E6_HUMAN,tr|F5H1H2|F5H1H2_HUMAN,tr|A0A0C4DGG8|A0A0C4DGG8_HUMAN,tr|F5H3E1|F5H3E1_HUMAN" 5 1750.8092 3.44 17767 18498 3 1750.808937 584.6104 Cell division cycle and apoptosis regulator protein 1 OS=Homo sapiens OX=9606 GN=CCAR1 PE=1 SV=2 5.32 3316.6 - 2.01E+06 - - - -0.1702 - 2.003 0.32 - 93.4 1 2 0 -0.0003 15 0 0 0 4.75E+07 1.38E+07 - - - 3.9202 0.999 221125_WJC_METTL3_EV_vs_WT_F02.18499.18499.2 0.055 22-Sep K.AVC[160.03]VEAGMIALR.R "sp|P17980|PRS6A_HUMAN,tr|R4GNH3|R4GNH3_HUMAN,tr|E9PM69|E9PM69_HUMAN" 3 1288.6632 0.97 17768 18499 2 1288.663073 645.3389 26S proteasome regulatory subunit 6A OS=Homo sapiens OX=9606 GN=PSMC3 PE=1 SV=3 6.04 3316.7 - 855135 - - - -0.0698 - 1.49 0.31 - 169.2 1 2 0 -0.0001 12 0 0 0 1.79E+07 1.84E+07 - - - 2.3799 0.9986 221125_WJC_METTL3_EV_vs_WT_F02.18503.18503.2 0.0418 16-Sep K.VSVIQDFVK[136.11].M sp|Q9UFW8|CGBP1_HUMAN 1 1041.595 0.84 17770 18503 2 1041.594971 521.8048 CGG triplet repeat-binding protein 1 OS=Homo sapiens OX=9606 GN=CGGBP1 PE=1 SV=2 5.81 3317.2 - 2.20E+06 - - - -0.025 - 1.506 0.252 - 258.8 1 2 0 0 9 0 0 0 6.59E+07 7.83E+07 - - - 2.0868 0.9999 221125_WJC_METTL3_EV_vs_WT_F02.18504.18504.3 0.00025 Dec-56 K.VMLMASPSMEDLYHK[136.11].S "sp|Q8IX12|CCAR1_HUMAN,tr|F5H2E6|F5H2E6_HUMAN,tr|F5H1H2|F5H1H2_HUMAN,tr|A0A0C4DGG8|A0A0C4DGG8_HUMAN,tr|F5H3E1|F5H3E1_HUMAN" 5 1758.8234 3.4 17771 18504 3 1758.820559 587.2818 Cell division cycle and apoptosis regulator protein 1 OS=Homo sapiens OX=9606 GN=CCAR1 PE=1 SV=2 5.32 3317.3 - 1.01E+06 - - - -1.6352 - 2.698 0.45 - 153 1 2 0 -0.0029 15 0 0 0 4.80E+07 1.41E+07 - - - 6.1461 0.9995 221125_WJC_METTL3_EV_vs_WT_F02.18505.18505.2 0.505 18-Sep R.DIIC[160.03]QIAYAR[166.11].L "sp|P46777|RL5_HUMAN,tr|A0A2R8Y6J3|A0A2R8Y6J3_HUMAN,tr|A0A2R8Y4A2|A0A2R8Y4A2_HUMAN,tr|Q5T7N0|Q5T7N0_HUMAN" 4 1231.6259 0.5 17772 18505 2 1231.62381 616.8202 60S ribosomal protein L5 OS=Homo sapiens OX=9606 GN=RPL5 PE=1 SV=3 5.83 3317.4 - 2.83E+06 - - - -1.6669 - 1.919 0.386 - 348.6 1 2 0 -0.0021 10 0 0 0 4.62E+07 9.18E+07 - - - 3.7107 0.9884 221125_WJC_METTL3_EV_vs_WT_F02.18507.18507.2 0.00533 13/26 R.ELGEYGLQAYTEVK.T sp|P05091|ALDH2_HUMAN 1 1598.7828 1.36 17774 18507 2 1598.773131 800.3987 "Aldehyde dehydrogenase, mitochondrial OS=Homo sapiens OX=9606 GN=ALDH2 PE=1 SV=2" 4.25 3317.5 - 878087 - - - -6.0502 - 1.98 0.387 - 296 1 2 0 -0.0097 14 0 0 0 6.08E+06 4.48E+06 - - - 3.6105 1 221125_WJC_METTL3_EV_vs_WT_F02.18508.18508.2 2.13E-09 14/28 R.LLGTPTEEQWPSMTK[136.11].L sp|Q00535|CDK5_HUMAN 1 1724.8535 0.96 17775 18508 2 1724.85129 863.434 Cyclin-dependent-like kinase 5 OS=Homo sapiens OX=9606 GN=CDK5 PE=1 SV=3 4.53 3317.7 - 773896 - - - -1.2656 - 2.516 0.65 - 548.9 1 2 0 -0.0022 15 0 0 0 8.31E+06 8.67E+06 - - - 6.1096 0.9998 221125_WJC_METTL3_EV_vs_WT_F02.18511.18511.2 6.65E-05 18-Oct K.FAAQELIEVK[136.11].R "sp|Q86U44|MTA70_HUMAN,tr|F5H6D8|F5H6D8_HUMAN,tr|H0YFV6|H0YFV6_HUMAN,tr|B4DTN4|B4DTN4_HUMAN" 4 1154.6427 0 17777 18511 2 1154.641669 578.3286 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 4.53 3318 - 1.77E+07 - - - -0.8713 - 2.064 0.491 - 281.5 1 2 0 -0.001 10 0 0 0 1.80E+06 5.78E+08 - - - 4.6899 1 221125_WJC_METTL3_EV_vs_WT_F02.18513.18513.2 6.25E-08 13/22 K.YGGDEIPFSPYR.V "sp|P21333|FLNA_HUMAN,tr|Q60FE5|Q60FE5_HUMAN" 2 1399.6408 0.96 17778 18513 2 1399.640293 700.8277 Filamin-A OS=Homo sapiens OX=9606 GN=FLNA PE=1 SV=4 4.37 3318.2 - 3.00E+06 - - - -0.3844 - 2.686 0.593 - 447.6 1 2 0 -0.0005 12 0 0 0 5.53E+07 5.78E+07 - - - 6.0205 0.999 221125_WJC_METTL3_EV_vs_WT_F02.18518.18518.2 0.000227 22-Aug R.EGPYGLIIC[160.03]PSR[166.11].E "sp|Q9UJV9|DDX41_HUMAN,tr|A0A499FJW5|A0A499FJW5_HUMAN,tr|H0Y8L8|H0Y8L8_HUMAN" 3 1370.6892 0.38 17783 18518 2 1370.691826 686.3519 Probable ATP-dependent RNA helicase DDX41 OS=Homo sapiens OX=9606 GN=DDX41 PE=1 SV=2 6.09 3318.9 - 760357 - - - 1.9217 - 1.837 0.343 - 251.6 1 2 0 0.0026 12 0 0 0 8.40E+06 2.20E+07 - - - 3.1737 0.9998 221125_WJC_METTL3_EV_vs_WT_F02.18521.18521.2 1.71E-06 26-Nov K.EIFEQPESVVNTMR.G "sp|Q06210|GFPT1_HUMAN,tr|A0A6I8PRN4|A0A6I8PRN4_HUMAN,tr|A0A6I8PTT9|A0A6I8PTT9_HUMAN" 3 1677.8032 1.14 17786 18521 2 1677.800074 839.9089 Glutamine--fructose-6-phosphate aminotransferase [isomerizing] 1 OS=Homo sapiens OX=9606 GN=GFPT1 PE=1 SV=3 4.25 3319.3 - 433632 - - - -1.8757 - 2.575 0.558 - 259.7 1 2 0 -0.0031 14 0 0 0 9.12E+06 8.01E+06 - - - 5.535 0.9999 221125_WJC_METTL3_EV_vs_WT_F02.18523.18523.2 2.67E-06 18-Oct R.FVNVVPTFGK[136.11].K "sp|P62861|RS30_HUMAN,tr|E9PR30|E9PR30_HUMAN" 2 1114.6266 0.44 17787 18523 2 1114.626119 558.3206 40S ribosomal protein S30 OS=Homo sapiens OX=9606 GN=FAU PE=1 SV=1 8.75 3319.5 - 2.11E+07 - - - -0.4593 - 2.106 0.571 - 338.5 1 2 0 -0.0005 10 0 0 0 1.72E+08 3.94E+08 - - - 5.3372 0.9998 221125_WJC_METTL3_EV_vs_WT_F02.18525.18525.2 0.000342 16-Oct K.VSVIQDFVK.M sp|Q9UFW8|CGBP1_HUMAN 1 1033.5808 0.76 17788 18525 2 1033.580484 517.7977 CGG triplet repeat-binding protein 1 OS=Homo sapiens OX=9606 GN=CGGBP1 PE=1 SV=2 5.81 3319.7 - 3.95E+06 - - - -0.3028 - 2.081 0.415 - 295.4 1 2 0 -0.0003 9 0 0 0 5.81E+07 7.69E+07 - - - 4.2263 0.9999 221125_WJC_METTL3_EV_vs_WT_F02.18529.18529.2 0.00265 14/20 R.ALAAQLPVLPR.S "sp|Q96GK7|FAH2A_HUMAN,tr|C9JGM0|C9JGM0_HUMAN" 2 1147.7077 1.03 17792 18529 2 1147.707489 574.8611 Fumarylacetoacetate hydrolase domain-containing protein 2A OS=Homo sapiens OX=9606 GN=FAHD2A PE=1 SV=1 9.79 3320 - 1.73E+06 - - - -0.2082 - 2.655 0.43 - 716.3 1 2 0 -0.0002 11 0 0 0 2.49E+07 2.42E+07 - - - 4.8584 0.9712 221125_WJC_METTL3_EV_vs_WT_F02.18530.18530.2 2.79 12-Jun K.QFLDFGR.D sp|Q15120|PDK3_HUMAN 1 881.4396 1.01 17793 18530 2 881.438448 441.7271 "[Pyruvate dehydrogenase (acetyl-transferring)] kinase isozyme 3, mitochondrial OS=Homo sapiens OX=9606 GN=PDK3 PE=1 SV=1" 5.84 3320.1 - 2.42E+06 - - - -1.2525 - 0.995 0.147 - 99.9 1 2 0 -0.0011 7 0 0 0 6.48E+06 6.39E+06 - - - 0.1105 0.9999 221125_WJC_METTL3_EV_vs_WT_F02.18532.18532.2 1.22E-05 24-Nov R.MVIITGPPEAQFK[136.11].A "sp|Q9NZI8|IF2B1_HUMAN,sp|O00425|IF2B3_HUMAN,sp|Q9Y6M1|IF2B2_HUMAN,tr|F8W930|F8W930_HUMAN" 4 1437.7781 1.62 17794 18532 2 1437.777466 719.8963 Insulin-like growth factor 2 mRNA-binding protein 1 OS=Homo sapiens OX=9606 GN=IGF2BP1 PE=1 SV=2 5.75 3320.4 - 1.96E+07 - - - -0.457 - 2.282 0.489 - 310.6 1 2 0 -0.0007 13 0 0 0 1.37E+09 8.48E+08 - - - 4.7701 0.9998 221125_WJC_METTL3_EV_vs_WT_F02.18534.18534.2 4.60E-05 16-Oct R.QVTIWFQNR.R "sp|P31271|HXA13_HUMAN,sp|P35453|HXD13_HUMAN,sp|P31276|HXC13_HUMAN" 3 1190.6196 0.11 17795 18534 2 1190.619397 596.3171 Homeobox protein Hox-A13 OS=Homo sapiens OX=9606 GN=HOXA13 PE=1 SV=3 9.75 3320.6 - 3.73E+06 - - - -0.2058 - 1.87 0.482 - 553.4 1 2 0 -0.0002 9 0 0 0 3.82E+07 3.40E+08 - - - 4.4118 0.9999 221125_WJC_METTL3_EV_vs_WT_F02.18535.18535.2 3.59E-07 26-Dec R.IWSVPNASC[160.03]VQVVR.A sp|Q9UMS4|PRP19_HUMAN 1 1613.8348 1.61 17796 18535 2 1613.833991 807.9247 Pre-mRNA-processing factor 19 OS=Homo sapiens OX=9606 GN=PRPF19 PE=1 SV=1 8.25 3320.6 - 2.15E+06 - - - -0.4994 - 2.201 0.493 - 290.7 1 2 0 -0.0008 14 0 0 0 6.66E+07 4.13E+07 - - - 4.6618 1 221125_WJC_METTL3_EV_vs_WT_F02.18536.18536.2 1.61E-06 22-Oct K.YGGDEIPFSPYR[166.11].V "sp|P21333|FLNA_HUMAN,tr|Q60FE5|Q60FE5_HUMAN" 2 1409.6491 0.96 17797 18536 2 1409.650436 705.8318 Filamin-A OS=Homo sapiens OX=9606 GN=FLNA PE=1 SV=4 4.37 3320.7 - 2.34E+06 - - - 0.947 - 2.476 0.616 - 197.3 1 2 0 0.0013 12 0 0 0 5.53E+07 5.78E+07 - - - 5.9759 1 221125_WJC_METTL3_EV_vs_WT_F02.18537.18537.2 5.00E-06 15/26 R.IWSVPNASC[160.03]VQVVR[166.11].A sp|Q9UMS4|PRP19_HUMAN 1 1623.8431 1.51 17798 18537 2 1623.842452 812.9288 Pre-mRNA-processing factor 19 OS=Homo sapiens OX=9606 GN=PRPF19 PE=1 SV=1 8.25 3320.9 - 2.17E+06 - - - -0.3787 - 2.464 0.599 - 522.1 1 2 0 -0.0006 14 0 0 0 6.22E+07 4.13E+07 - - - 5.728 0.9998 221125_WJC_METTL3_EV_vs_WT_F02.18538.18538.2 5.41E-07 20-Nov R.YNTILQMYGEK[136.11].A "sp|P82094|TMF1_HUMAN,tr|A0A2R8Y7M0|A0A2R8Y7M0_HUMAN" 2 1366.6682 0.86 17799 18538 2 1366.666612 684.3414 TATA element modulatory factor OS=Homo sapiens OX=9606 GN=TMF1 PE=1 SV=2 6 3321 - 1.48E+06 - - - -1.1898 - 2.278 0.46 - 405.8 1 2 0 -0.0016 11 0 0 0 3.78E+07 4.42E+07 - - - 4.6653 0.9908 221125_WJC_METTL3_EV_vs_WT_F02.18541.18541.2 0.52 12-Sep K.QFLDFGR[166.11].D sp|Q15120|PDK3_HUMAN 1 891.4478 1.01 17802 18541 2 891.446446 446.7312 "[Pyruvate dehydrogenase (acetyl-transferring)] kinase isozyme 3, mitochondrial OS=Homo sapiens OX=9606 GN=PDK3 PE=1 SV=1" 5.84 3321.3 - 618056 - - - -1.5436 - 1.312 0.148 - 350.4 1 2 0 -0.0014 7 0 0 0 6.48E+06 6.39E+06 - - - 0.9941 0.9872 221125_WJC_METTL3_EV_vs_WT_F02.18542.18542.2 0.345 24-Jun K.GAIVFNATSEFC[160.03]R.T sp|O43290|SNUT1_HUMAN 1 1470.6925 7.65 17803 18542 2 1470.692108 736.3536 U4\U6.U5 tri-snRNP-associated protein 1 OS=Homo sapiens OX=9606 GN=SART1 PE=1 SV=1 5.99 3321.5 - 829323 - - - -0.2999 - 1.548 0.068 - 93.3 3 2 0 -0.0004 13 0 0 0 1.50E+06 1.97E+05 - - - 0.4515 0.9995 221125_WJC_METTL3_EV_vs_WT_F02.18546.18546.2 0.0461 14-Aug K.AGPIWDLR[166.11].L "sp|O60506|HNRPQ_HUMAN,sp|O43390|HNRPR_HUMAN,tr|B4DT28|B4DT28_HUMAN,tr|A0A7I2YQN2|A0A7I2YQN2_HUMAN,tr|A0A7I2V5Q6|A0A7I2V5Q6_HUMAN,tr|A0A7I2V4Z0|A0A7I2V4Z0_HUMAN,tr|B7Z645|B7Z645_HUMAN,tr|A0A6Q8PH31|A0A6Q8PH31_HUMAN,tr|A0A6Q8PEX7|A0A6Q8PEX7_HUMAN,tr|A0A7I2V2F2|A0A7I2V2F2_HUMAN,tr|A0A7I2V346|A0A7I2V346_HUMAN,tr|A0A7I2V309|A0A7I2V309_HUMAN,tr|A0A6Q8PH35|A0A6Q8PH35_HUMAN" 13 936.5057 1.2 17805 18546 2 936.505312 469.2601 Heterogeneous nuclear ribonucleoprotein Q OS=Homo sapiens OX=9606 GN=SYNCRIP PE=1 SV=2 5.88 3321.9 - 4.30E+06 - - - -0.3833 - 1.58 0.355 - 304 1 2 0 -0.0004 8 0 0 0 6.52E+07 5.45E+07 - - - 3.0425 0.9998 221125_WJC_METTL3_EV_vs_WT_F02.18548.18548.2 3.49E-05 20-Sep K.DANLYISGLPR[166.11].T "sp|Q15717|ELAV1_HUMAN,tr|M0R055|M0R055_HUMAN,tr|M0QZR9|M0QZR9_HUMAN" 3 1227.6487 1.36 17807 18548 2 1227.649927 614.8316 ELAV-like protein 1 OS=Homo sapiens OX=9606 GN=ELAVL1 PE=1 SV=2 5.84 3322 - 4.10E+06 - - - 0.9938 - 2.041 0.456 - 353.8 1 2 0 0.0012 11 0 0 0 4.23E+08 3.10E+08 - - - 4.3387 0.9998 221125_WJC_METTL3_EV_vs_WT_F02.18549.18549.2 0.00532 18-Dec K.IDTIEIITDR.Q "sp|P22626|ROA2_HUMAN,tr|A0A7I2YQN4|A0A7I2YQN4_HUMAN,tr|A0A7I2V4N0|A0A7I2V4N0_HUMAN,tr|A0A024RA28|A0A024RA28_HUMAN,tr|A0A7I2V4N1|A0A7I2V4N1_HUMAN,tr|A0A7I2V4I6|A0A7I2V4I6_HUMAN,tr|A0A087WUI2|A0A087WUI2_HUMAN,tr|A0A7I2V4S4|A0A7I2V4S4_HUMAN,tr|A0A7I2V323|A0A7I2V323_HUMAN,tr|A0A7I2V3P1|A0A7I2V3P1_HUMAN,tr|A0A7I2V3P7|A0A7I2V3P7_HUMAN" 11 1187.6398 1.32 17808 18549 2 1187.638509 594.8272 Heterogeneous nuclear ribonucleoproteins A2\B1 OS=Homo sapiens OX=9606 GN=HNRNPA2B1 PE=1 SV=2 4.03 3322.1 - 3.34E+06 - - - -1.0601 - 2.511 0.394 - 639.6 1 2 0 -0.0013 10 0 0 0 1.83E+09 1.39E+09 - - - 4.5206 0.9997 221125_WJC_METTL3_EV_vs_WT_F02.18550.18550.2 0.000963 22-Nov K.SVLAETEGILQK.L "sp|Q86UP2|KTN1_HUMAN,tr|B7Z6P3|B7Z6P3_HUMAN,tr|G3V5P0|G3V5P0_HUMAN,tr|G3V4Y7|G3V4Y7_HUMAN" 4 1286.7082 0.47 17809 18550 2 1286.709775 644.3614 Kinectin OS=Homo sapiens OX=9606 GN=KTN1 PE=1 SV=1 4.53 3322.1 - 1.78E+06 - - - 1.238 - 2.361 0.39 - 358.6 1 2 0 0.0016 12 0 0 0 3.26E+07 6.91E+07 - - - 4.1814 1 221125_WJC_METTL3_EV_vs_WT_F02.18551.18551.3 1.02E-06 15/52 R.IWSVPNASC[160.03]VQVVR.A sp|Q9UMS4|PRP19_HUMAN 1 1613.8348 1.01 17810 18551 3 1613.834883 538.9522 Pre-mRNA-processing factor 19 OS=Homo sapiens OX=9606 GN=PRPF19 PE=1 SV=1 8.25 3322.2 - 1.43E+06 - - - 0.0533 - 2.968 0.529 - 324.1 1 2 0 0.0001 14 0 0 0 1.29E+07 1.27E+07 - - - 7.3289 1 221125_WJC_METTL3_EV_vs_WT_F02.18552.18552.2 6.58E-10 22-Dec R.EYTDVYPEIIER.A "sp|Q9Y5V3|MAGD1_HUMAN,sp|Q9UNF1|MAGD2_HUMAN,tr|Q5H907|Q5H907_HUMAN,tr|Q5H909|Q5H909_HUMAN" 4 1525.73 1.57 17811 18552 2 1525.728565 763.8723 Melanoma-associated antigen D1 OS=Homo sapiens OX=9606 GN=MAGED1 PE=1 SV=3 4 3322.3 - 1.24E+06 - - - -0.9668 - 2.327 0.666 - 486.5 1 2 0 -0.0015 12 0 0 0 4.27E+07 2.72E+07 - - - 6.1818 0.9999 221125_WJC_METTL3_EV_vs_WT_F02.18557.18557.3 0.00217 13/36 R.IEDFGLHFVR[166.11].E "sp|Q9BT40|INP5K_HUMAN,tr|C9JZB0|C9JZB0_HUMAN" 2 1241.6432 0.75 17816 18557 3 1241.642255 414.8884 Inositol polyphosphate 5-phosphatase K OS=Homo sapiens OX=9606 GN=INPP5K PE=1 SV=3 5.32 3322.9 - 430041 - - - -0.7828 - 2.642 0.376 - 199.2 1 2 0 -0.001 10 0 0 0 3.19E+06 4.26E+06 - - - 5.5691 0.9991 221125_WJC_METTL3_EV_vs_WT_F02.18563.18563.2 0.00535 14-Sep K.AGPIWDLR.L "sp|O60506|HNRPQ_HUMAN,sp|O43390|HNRPR_HUMAN,tr|B4DT28|B4DT28_HUMAN,tr|A0A7I2YQN2|A0A7I2YQN2_HUMAN,tr|A0A7I2V5Q6|A0A7I2V5Q6_HUMAN,tr|A0A7I2V4Z0|A0A7I2V4Z0_HUMAN,tr|B7Z645|B7Z645_HUMAN,tr|A0A6Q8PH31|A0A6Q8PH31_HUMAN,tr|A0A6Q8PEX7|A0A6Q8PEX7_HUMAN,tr|A0A7I2V2F2|A0A7I2V2F2_HUMAN,tr|A0A7I2V346|A0A7I2V346_HUMAN,tr|A0A7I2V309|A0A7I2V309_HUMAN,tr|A0A6Q8PH35|A0A6Q8PH35_HUMAN" 13 926.4974 1.16 17820 18563 2 926.497988 464.256 Heterogeneous nuclear ribonucleoprotein Q OS=Homo sapiens OX=9606 GN=SYNCRIP PE=1 SV=2 5.88 3323.7 - 6.31E+06 - - - 0.6336 - 1.692 0.267 - 376.9 1 2 0 0.0006 8 0 0 0 6.53E+07 5.65E+07 - - - 2.599 0.9996 221125_WJC_METTL3_EV_vs_WT_F02.18565.18565.2 0.00994 18-Dec K.ILDILGETC[160.03]K[136.11].S "sp|Q14151|SAFB2_HUMAN,sp|Q15424|SAFB1_HUMAN" 2 1168.6253 1.4 17822 18565 2 1168.628208 585.3199 Scaffold attachment factor B2 OS=Homo sapiens OX=9606 GN=SAFB2 PE=1 SV=1 4.37 3323.7 - 4.65E+06 - - - 2.479 - 2.592 0.435 - 460.1 1 2 0 0.0029 10 0 0 0 2.22E+08 1.59E+08 - - - 4.9115 0.9913 221125_WJC_METTL3_EV_vs_WT_F02.18566.18566.2 0.0331 16-Jul R.GSFPLPQLR[166.11].L sp|Q5JSZ5|PRC2B_HUMAN 1 1023.5741 1.99 17823 18566 2 1023.574212 512.7943 Protein PRRC2B OS=Homo sapiens OX=9606 GN=PRRC2B PE=1 SV=2 9.75 3323.8 - 3.78E+06 - - - 0.1241 - 1.172 0.165 - 116.6 1 2 0 0.0001 9 0 0 0 1.38E+08 6.92E+07 - - - 0.7188 0.9999 221125_WJC_METTL3_EV_vs_WT_F02.18568.18568.2 0.000103 13/22 K.SVLAETEGILQK[136.11].L "sp|Q86UP2|KTN1_HUMAN,tr|B7Z6P3|B7Z6P3_HUMAN,tr|G3V5P0|G3V5P0_HUMAN,tr|G3V4Y7|G3V4Y7_HUMAN" 4 1294.7224 0.47 17825 18568 2 1294.723053 648.3685 Kinectin OS=Homo sapiens OX=9606 GN=KTN1 PE=1 SV=1 4.53 3323.9 - 1.87E+06 - - - 0.5183 - 2.793 0.477 - 532.5 1 2 0 0.0007 12 0 0 0 3.22E+07 6.91E+07 - - - 5.2664 0.9915 221125_WJC_METTL3_EV_vs_WT_F02.18570.18570.2 5.71E-08 14/22 L.IGSVEEQLAQLR.C "sp|Q04695|K1C17_HUMAN,sp|P02533|K1C14_HUMAN,sp|P08779|K1C16_HUMAN,tr|A0A3B3IS58|A0A3B3IS58_HUMAN,tr|F5GWP8|F5GWP8_HUMAN,tr|K7ENW6|K7ENW6_HUMAN" 6 1341.7252 39.2 17827 18570 2 1341.72724 671.8699 "Keratin, type I cytoskeletal 17 OS=Homo sapiens OX=9606 GN=KRT17 PE=1 SV=2" 4.53 3324.2 - 1.70E+06 - - - 1.4988 - 2.92 0.515 - 988.9 1 1 0 0.002 12 0 0 0 1.90E+08 4.84E+06 - - - 5.6637 1 221125_WJC_METTL3_EV_vs_WT_F02.18571.18571.2 1.92E-09 13/26 R.FAQPGSFEYEYAMR.W "sp|Q15233|NONO_HUMAN,tr|A0A7I2V535|A0A7I2V535_HUMAN,tr|A0A7I2V4N2|A0A7I2V4N2_HUMAN,tr|A0A7I2V4K9|A0A7I2V4K9_HUMAN,tr|A0A7I2V464|A0A7I2V464_HUMAN,tr|A0A7P0MRW0|A0A7P0MRW0_HUMAN,tr|H7C367|H7C367_HUMAN,tr|A0A7I2V4J2|A0A7I2V4J2_HUMAN,tr|A0A7I2V5Y7|A0A7I2V5Y7_HUMAN,tr|C9JYS8|C9JYS8_HUMAN" 10 1694.7399 0.8 17828 18571 2 1694.742118 848.3772 Non-POU domain-containing octamer-binding protein OS=Homo sapiens OX=9606 GN=NONO PE=1 SV=4 4.53 3324.3 - 1.68E+06 - - - 1.3129 - 2.814 0.645 - 478.9 1 2 0 0.0022 14 0 0 0 1.19E+08 1.49E+08 - - - 6.4006 1 221125_WJC_METTL3_EV_vs_WT_F02.18573.18573.2 3.61E-08 15/30 R.VFLQGPAPVGTPSFNR.Q "sp|Q8IWZ3|ANKH1_HUMAN,tr|H0Y472|H0Y472_HUMAN,tr|H0Y4P6|H0Y4P6_HUMAN,tr|H7C0V5|H7C0V5_HUMAN,tr|H0Y785|H0Y785_HUMAN" 5 1685.8889 1.4 17830 18573 2 1685.891374 843.9517 Ankyrin repeat and KH domain-containing protein 1 OS=Homo sapiens OX=9606 GN=ANKHD1 PE=1 SV=1 9.72 3324.5 - 966907 - - - 1.4437 - 2.787 0.657 - 627.8 1 2 0 0.0024 16 0 0 0 7.43E+07 5.29E+07 - - - 6.4128 0.9991 221125_WJC_METTL3_EV_vs_WT_F02.18574.18574.2 0.163 16-Jul R.LALVDFGSR.E "sp|O43716|GATC_HUMAN,tr|H0YIV9|H0YIV9_HUMAN,tr|F8VRU3|F8VRU3_HUMAN" 3 976.5342 12.31 17831 18574 2 976.534412 489.2744 "Glutamyl-tRNA(Gln) amidotransferase subunit C, mitochondrial OS=Homo sapiens OX=9606 GN=GATC PE=1 SV=1" 5.84 3324.6 - 879250 - - - 0.2366 - 1.82 0.227 - 132.8 1 2 0 0.0002 9 0 0 0 4.68E+07 3.80E+06 - - - 2.45 0.9998 221125_WJC_METTL3_EV_vs_WT_F02.18575.18575.2 3.13E-05 22-Aug R.IEYVTVTPEGFR[166.11].Y sp|Q7KZ85|SPT6H_HUMAN 1 1419.7274 0.86 17832 18575 2 1419.726084 710.871 Transcription elongation factor SPT6 OS=Homo sapiens OX=9606 GN=SUPT6H PE=1 SV=2 4.53 3324.8 - 759522 - - - -0.8924 - 2.02 0.46 - 210.5 1 2 0 -0.0013 12 0 0 0 9.13E+06 1.06E+07 - - - 4.2881 0.9998 221125_WJC_METTL3_EV_vs_WT_F02.18576.18576.3 0.00266 Nov-44 K.SVLAETEGILQK.L "sp|Q86UP2|KTN1_HUMAN,tr|B7Z6P3|B7Z6P3_HUMAN,tr|G3V5P0|G3V5P0_HUMAN,tr|G3V4Y7|G3V4Y7_HUMAN" 4 1286.7082 4.33 17833 18576 3 1286.707811 429.91 Kinectin OS=Homo sapiens OX=9606 GN=KTN1 PE=1 SV=1 4.53 3324.9 - 664384 - - - -0.2883 - 1.944 0.384 - 173.6 1 2 0 -0.0004 12 0 0 0 5.90E+06 1.36E+06 - - - 4.6637 0.9999 221125_WJC_METTL3_EV_vs_WT_F02.18577.18577.3 0.000567 13/40 K.MLKPAFIFDGR.R sp|O60701|UGDH_HUMAN 1 1293.6904 1.56 17834 18577 3 1293.690587 432.2374 UDP-glucose 6-dehydrogenase OS=Homo sapiens OX=9606 GN=UGDH PE=1 SV=1 8.5 3325 - 553366 - - - 0.1724 - 2.124 0.394 - 219.1 1 2 0 0.0002 11 0 0 0 8.55E+06 5.49E+06 - - - 5.0726 0.9999 221125_WJC_METTL3_EV_vs_WT_F02.18579.18579.3 0.000133 Dec-40 K.DANLYISGLPR[166.11].T "sp|Q15717|ELAV1_HUMAN,tr|M0R055|M0R055_HUMAN,tr|M0QZR9|M0QZR9_HUMAN" 3 1227.6487 1.61 17836 18579 3 1227.645458 410.2235 ELAV-like protein 1 OS=Homo sapiens OX=9606 GN=ELAVL1 PE=1 SV=2 5.84 3325.3 - 419066 - - - -2.6465 - 2.529 0.481 - 179 1 2 0 -0.0032 11 0 0 0 1.26E+07 7.87E+06 - - - 6.5376 0.9997 221125_WJC_METTL3_EV_vs_WT_F02.18583.18583.2 0.000238 20-Oct K.SEEGPGWTILR[166.11].D sp|Q9Y3B9|RRP15_HUMAN 1 1253.628 1.06 17839 18583 2 1253.626225 627.8213 RRP15-like protein OS=Homo sapiens OX=9606 GN=RRP15 PE=1 SV=2 4.53 3325.7 - 1.63E+06 - - - -1.3928 - 2.115 0.421 - 472.6 1 2 0 -0.0017 11 0 0 0 1.66E+07 1.58E+07 - - - 4.1763 0.9999 221125_WJC_METTL3_EV_vs_WT_F02.18586.18586.2 2.57E-05 22-Dec K.YNILGTNTIMDK[136.11].M "sp|Q00839|HNRPU_HUMAN,tr|A0A1W2PQL0|A0A1W2PQL0_HUMAN,tr|A0A1W2PPL4|A0A1W2PPL4_HUMAN,tr|A0A1W2PQ74|A0A1W2PQ74_HUMAN,tr|Q5RI18|Q5RI18_HUMAN,tr|A0A1W2PP35|A0A1W2PP35_HUMAN,tr|A0A1W2PPS1|A0A1W2PPS1_HUMAN,tr|A0A1W2PRZ7|A0A1W2PRZ7_HUMAN,tr|A0A1W2PPH7|A0A1W2PPH7_HUMAN,tr|A0A1W2PQD4|A0A1W2PQD4_HUMAN,tr|A0A1W2PP34|A0A1W2PP34_HUMAN,tr|A0A1X7SBS1|A0A1X7SBS1_HUMAN" 12 1389.7054 0.93 17841 18586 2 1389.705571 695.86 Heterogeneous nuclear ribonucleoprotein U OS=Homo sapiens OX=9606 GN=HNRNPU PE=1 SV=6 5.83 3326 - 7.62E+06 - - - 0.1576 - 2.405 0.488 - 401.4 1 2 0 0.0002 12 0 0 0 4.12E+09 4.43E+09 - - - 4.9543 1 221125_WJC_METTL3_EV_vs_WT_F02.18587.18587.2 2.02E-10 13/26 R.FAQPGSFEYEYAMR[166.11].W "sp|Q15233|NONO_HUMAN,tr|A0A7I2V535|A0A7I2V535_HUMAN,tr|A0A7I2V4N2|A0A7I2V4N2_HUMAN,tr|A0A7I2V4K9|A0A7I2V4K9_HUMAN,tr|A0A7I2V464|A0A7I2V464_HUMAN,tr|A0A7P0MRW0|A0A7P0MRW0_HUMAN,tr|H7C367|H7C367_HUMAN,tr|A0A7I2V4J2|A0A7I2V4J2_HUMAN,tr|A0A7I2V5Y7|A0A7I2V5Y7_HUMAN,tr|C9JYS8|C9JYS8_HUMAN" 10 1704.7482 0.8 17842 18587 2 1704.748972 853.3814 Non-POU domain-containing octamer-binding protein OS=Homo sapiens OX=9606 GN=NONO PE=1 SV=4 4.53 3326 - 6.22E+06 - - - 0.4746 - 2.895 0.746 - 493.8 1 2 0 0.0008 14 0 0 0 1.19E+08 1.49E+08 - - - 7.2182 0.9998 221125_WJC_METTL3_EV_vs_WT_F02.18589.18589.2 5.81E-05 18-Nov K.TYIQTELPFK.A "sp|O95785|WIZ_HUMAN,tr|A0A669KBG4|A0A669KBG4_HUMAN,tr|A0A2R8YFV2|A0A2R8YFV2_HUMAN,tr|A0A669KAV7|A0A669KAV7_HUMAN,tr|M0QXA7|M0QXA7_HUMAN,tr|A0A669KBH9|A0A669KBH9_HUMAN,tr|B9EGQ5|B9EGQ5_HUMAN" 7 1238.6547 1.09 17844 18589 2 1238.654867 620.3346 Protein Wiz OS=Homo sapiens OX=9606 GN=WIZ PE=1 SV=2 5.66 3326.1 - 2.53E+06 - - - 0.1429 - 1.916 0.477 - 366.6 1 2 0 0.0002 10 0 0 0 8.51E+07 7.82E+07 - - - 4.3791 0.9997 221125_WJC_METTL3_EV_vs_WT_F02.18590.18590.2 0.00644 18-Nov R.GLQEIEESLR[166.11].S "sp|Q8WV92|MITD1_HUMAN,tr|B8ZZL5|B8ZZL5_HUMAN,tr|H7C3Q6|H7C3Q6_HUMAN" 3 1182.612 1.42 17845 18590 2 1182.612754 592.3133 MIT domain-containing protein 1 OS=Homo sapiens OX=9606 GN=MITD1 PE=1 SV=1 4.25 3326.2 - 2.15E+06 - - - 0.6486 - 2.216 0.335 - 554.8 1 2 0 0.0008 10 0 0 0 7.72E+07 5.42E+07 - - - 3.7361 0.9999 221125_WJC_METTL3_EV_vs_WT_F02.18591.18591.2 9.54E-08 13/22 R.GYISPYFINTSK[136.11].G "sp|P10809|CH60_HUMAN,tr|A0A7I2V2X6|A0A7I2V2X6_HUMAN,tr|A0A7I2V599|A0A7I2V599_HUMAN,tr|A0A7I2YQ71|A0A7I2YQ71_HUMAN,tr|E7ESH4|E7ESH4_HUMAN,tr|A0A7I2V5M1|A0A7I2V5M1_HUMAN,tr|A0A7I2V5K3|A0A7I2V5K3_HUMAN,tr|A0A7I2V369|A0A7I2V369_HUMAN" 8 1396.7118 1.56 17846 18591 2 1396.712356 699.3632 "60 kDa heat shock protein, mitochondrial OS=Homo sapiens OX=9606 GN=HSPD1 PE=1 SV=2" 8.5 3326.3 - 982681 - - - 0.3859 - 2.397 0.55 - 652.4 1 2 0 0.0005 12 0 0 0 1.38E+10 8.82E+09 - - - 5.4033 0.9999 221125_WJC_METTL3_EV_vs_WT_F02.18593.18593.2 1.65E-06 24-Dec R.LPPGFNDVDALC[160.03]R.A "sp|Q8IY67|RAVR1_HUMAN,tr|E9PAU2|E9PAU2_HUMAN,tr|A0A087WZ13|A0A087WZ13_HUMAN" 3 1472.7082 0.88 17848 18593 2 1472.708853 737.3614 Ribonucleoprotein PTB-binding 1 OS=Homo sapiens OX=9606 GN=RAVER1 PE=1 SV=1 4.21 3326.6 - 882362 - - - 0.4441 - 2.217 0.54 - 313.6 1 2 0 0.0007 13 0 0 0 1.08E+08 1.22E+08 - - - 5.0726 0.9997 221125_WJC_METTL3_EV_vs_WT_F02.18594.18594.2 0.000124 18-Nov K.ILETTTFFQR[166.11].A sp|Q9NYU2|UGGG1_HUMAN 1 1264.6691 0.11 17849 18594 2 1264.67115 633.3418 UDP-glucose:glycoprotein glucosyltransferase 1 OS=Homo sapiens OX=9606 GN=UGGT1 PE=1 SV=3 6 3326.6 - 803594 - - - 1.6147 - 2.06 0.449 - 447.7 1 2 0 0.002 10 0 0 0 1.13E+07 1.06E+08 - - - 4.374 1 221125_WJC_METTL3_EV_vs_WT_F02.18596.18596.2 8.99E-09 15/28 R.SVMAAAQVAGLNC[160.03]LR[166.11].L "sp|O95757|HS74L_HUMAN,tr|D6RJ96|D6RJ96_HUMAN,tr|E9PDE8|E9PDE8_HUMAN" 3 1569.7995 0.02 17851 18596 2 1569.801194 785.907 Heat shock 70 kDa protein 4L OS=Homo sapiens OX=9606 GN=HSPA4L PE=1 SV=3 7.96 3326.9 - 519929 - - - 1.0874 - 3.494 0.616 - 813.5 1 2 0 0.0017 15 0 0 0 1.39E+05 5.60E+06 - - - 6.666 0.9932 221125_WJC_METTL3_EV_vs_WT_F02.18597.18597.2 0.193 16-Aug K.NVTLPAVFK[136.11].A "sp|P36578|RL4_HUMAN,tr|H3BTP7|H3BTP7_HUMAN,tr|H3BU31|H3BU31_HUMAN" 3 995.5895 1.71 17852 18597 2 995.58979 498.802 60S ribosomal protein L4 OS=Homo sapiens OX=9606 GN=RPL4 PE=1 SV=5 8.75 3327 - 418279 - - - 0.2742 - 1.298 0.151 - 128.6 1 2 0 0.0003 9 0 0 0 6.29E+07 3.68E+07 - - - 0.9108 0.9872 221125_WJC_METTL3_EV_vs_WT_F02.18599.18599.2 0.809 14-Jun K.GSLVDYLR.S sp|P41240|CSK_HUMAN 1 921.492 0.74 17854 18599 2 921.493836 461.7533 Tyrosine-protein kinase CSK OS=Homo sapiens OX=9606 GN=CSK PE=1 SV=1 5.84 3327.3 - 348458 - - - 2.012 - 1.295 0.164 - 88.8 1 2 0 0.0019 8 0 0 0 3.82E+06 5.15E+06 - - - 1.0314 0.9742 221125_WJC_METTL3_EV_vs_WT_F02.18600.18600.3 0.00995 Sep-36 K.IDTIEIITDR.Q "sp|P22626|ROA2_HUMAN,tr|A0A7I2YQN4|A0A7I2YQN4_HUMAN,tr|A0A7I2V4N0|A0A7I2V4N0_HUMAN,tr|A0A024RA28|A0A024RA28_HUMAN,tr|A0A7I2V4N1|A0A7I2V4N1_HUMAN,tr|A0A7I2V4I6|A0A7I2V4I6_HUMAN,tr|A0A087WUI2|A0A087WUI2_HUMAN,tr|A0A7I2V4S4|A0A7I2V4S4_HUMAN,tr|A0A7I2V323|A0A7I2V323_HUMAN,tr|A0A7I2V3P1|A0A7I2V3P1_HUMAN,tr|A0A7I2V3P7|A0A7I2V3P7_HUMAN" 11 1187.6398 0.81 17855 18600 3 1187.640412 396.8872 Heterogeneous nuclear ribonucleoproteins A2\B1 OS=Homo sapiens OX=9606 GN=HNRNPA2B1 PE=1 SV=2 4.03 3327.4 - 292663 - - - 0.5423 - 1.803 0.088 - 92.6 1 2 0 0.0006 10 0 0 0 8.81E+06 1.09E+07 - - - 1.2424 0.9885 221125_WJC_METTL3_EV_vs_WT_F02.18601.18601.2 0.526 16-Sep K.AILVVFANK[136.11].Q "sp|P40616|ARL1_HUMAN,tr|B4DZG7|B4DZG7_HUMAN,tr|F8VYN9|F8VYN9_HUMAN" 3 981.6103 0.53 17856 18601 2 981.611266 491.8124 ADP-ribosylation factor-like protein 1 OS=Homo sapiens OX=9606 GN=ARL1 PE=1 SV=1 8.8 3327.5 - 240847 - - - 1.032 - 1.202 0.156 - 155.5 1 2 0 0.001 9 0 0 0 1.54E+06 2.92E+06 - - - 0.7252 0.9999 221125_WJC_METTL3_EV_vs_WT_F02.18604.18604.2 1.82E-05 20-Nov K.DANLYISGLPR.T "sp|Q15717|ELAV1_HUMAN,tr|M0R055|M0R055_HUMAN,tr|M0QZR9|M0QZR9_HUMAN" 3 1217.6404 1.36 17857 18604 2 1217.640443 609.8275 ELAV-like protein 1 OS=Homo sapiens OX=9606 GN=ELAVL1 PE=1 SV=2 5.84 3327.9 - 3.04E+07 - - - 0.0049 - 2.511 0.468 - 574.2 1 2 0 0 11 0 0 0 4.23E+08 3.10E+08 - - - 4.9883 1 221125_WJC_METTL3_EV_vs_WT_F02.18605.18605.3 6.42E-09 14/52 R.FAQPGSFEYEYAMR[166.11].W "sp|Q15233|NONO_HUMAN,tr|A0A7I2V535|A0A7I2V535_HUMAN,tr|A0A7I2V4N2|A0A7I2V4N2_HUMAN,tr|A0A7I2V4K9|A0A7I2V4K9_HUMAN,tr|A0A7I2V464|A0A7I2V464_HUMAN,tr|A0A7P0MRW0|A0A7P0MRW0_HUMAN,tr|H7C367|H7C367_HUMAN,tr|A0A7I2V4J2|A0A7I2V4J2_HUMAN,tr|A0A7I2V5Y7|A0A7I2V5Y7_HUMAN,tr|C9JYS8|C9JYS8_HUMAN" 10 1704.7482 1.12 17858 18605 3 1704.748345 569.2567 Non-POU domain-containing octamer-binding protein OS=Homo sapiens OX=9606 GN=NONO PE=1 SV=4 4.53 3328 - 2.27E+06 - - - 0.1068 - 2.597 0.629 - 231.3 1 2 0 0.0002 14 0 0 0 3.04E+07 2.72E+07 - - - 8.0889 0.998 221125_WJC_METTL3_EV_vs_WT_F02.18607.18607.3 0.0168 Sep-52 R.FAQPGSFEYEYAMR.W "sp|Q15233|NONO_HUMAN,tr|A0A7I2V535|A0A7I2V535_HUMAN,tr|A0A7I2V4N2|A0A7I2V4N2_HUMAN,tr|A0A7I2V4K9|A0A7I2V4K9_HUMAN,tr|A0A7I2V464|A0A7I2V464_HUMAN,tr|A0A7P0MRW0|A0A7P0MRW0_HUMAN,tr|H7C367|H7C367_HUMAN,tr|A0A7I2V4J2|A0A7I2V4J2_HUMAN,tr|A0A7I2V5Y7|A0A7I2V5Y7_HUMAN,tr|C9JYS8|C9JYS8_HUMAN" 10 1694.7399 1.12 17860 18607 3 1694.744395 565.9206 Non-POU domain-containing octamer-binding protein OS=Homo sapiens OX=9606 GN=NONO PE=1 SV=4 4.53 3328.1 - 2.60E+06 - - - 2.6565 - 1.676 0.331 - 102.8 1 2 0 0.0045 14 0 0 0 3.04E+07 2.72E+07 - - - 3.6015 0.9994 221125_WJC_METTL3_EV_vs_WT_F02.18608.18608.2 0.000357 24-Dec R.LPPGFNDVDALC[160.03]R[166.11].A "sp|Q8IY67|RAVR1_HUMAN,tr|E9PAU2|E9PAU2_HUMAN,tr|A0A087WZ13|A0A087WZ13_HUMAN" 3 1482.7165 0.98 17861 18608 2 1482.719772 742.3655 Ribonucleoprotein PTB-binding 1 OS=Homo sapiens OX=9606 GN=RAVER1 PE=1 SV=1 4.21 3328.1 - 2.15E+06 - - - 2.2277 - 1.717 0.489 - 368 1 2 0 0.0033 13 0 0 0 9.56E+07 9.77E+07 - - - 4.0391 0.9999 221125_WJC_METTL3_EV_vs_WT_F02.18609.18609.2 5.14E-06 18-Dec R.QAFAPFGPIK[136.11].S "sp|Q9UHX1|PUF60_HUMAN,tr|A0A0J9YYL3|A0A0J9YYL3_HUMAN,tr|A0A0J9YWM1|A0A0J9YWM1_HUMAN,tr|H0YEM1|H0YEM1_HUMAN,tr|E9PMU7|E9PMU7_HUMAN,tr|E9PN18|E9PN18_HUMAN,tr|E9PL19|E9PL19_HUMAN,tr|A0A0J9YVR6|A0A0J9YVR6_HUMAN,tr|A0A0J9YXX5|A0A0J9YXX5_HUMAN,tr|A0A0J9YXJ8|A0A0J9YXJ8_HUMAN,tr|E9PQ56|E9PQ56_HUMAN,tr|H0YCP8|H0YCP8_HUMAN,tr|A0A0J9YVP6|A0A0J9YVP6_HUMAN" 13 1082.6004 1.22 17862 18609 2 1082.600165 542.3075 Poly(U)-binding-splicing factor PUF60 OS=Homo sapiens OX=9606 GN=PUF60 PE=1 SV=1 8.75 3328.2 - 1.94E+06 - - - -0.2318 - 2.136 0.456 - 476.6 1 2 0 -0.0003 10 0 0 0 1.28E+08 1.05E+08 - - - 4.5274 1 221125_WJC_METTL3_EV_vs_WT_F02.18611.18611.2 7.35E-09 13/28 R.YSQTGNYELAVALSR[166.11].W "sp|P39656|OST48_HUMAN,tr|A0A0C4DGS1|A0A0C4DGS1_HUMAN" 2 1680.8347 1.2 17864 18611 2 1680.839351 841.4246 Dolichyl-diphosphooligosaccharide--protein glycosyltransferase 48 kDa subunit OS=Homo sapiens OX=9606 GN=DDOST PE=1 SV=4 6 3328.5 - 1.12E+06 - - - 2.7849 - 2.85 0.627 - 547.3 1 2 0 0.0047 15 0 0 0 2.29E+07 1.91E+07 - - - 6.2454 0.9985 221125_WJC_METTL3_EV_vs_WT_F02.18612.18612.2 6.36E-06 16-Sep R.GC[160.03]ILTLVER[166.11].M "sp|Q99613|EIF3C_HUMAN,sp|B5ME19|EIFCL_HUMAN" 2 1069.5829 0.87 17865 18612 2 1069.587284 535.7987 Eukaryotic translation initiation factor 3 subunit C OS=Homo sapiens OX=9606 GN=EIF3C PE=1 SV=1 5.99 3328.6 - 1.05E+06 - - - 4.0651 - 1.919 0.481 - 373.6 1 2 0 0.0043 9 0 0 0 1.22E+07 1.40E+07 - - - 4.478 1 221125_WJC_METTL3_EV_vs_WT_F02.18613.18613.2 4.22E-11 15/28 R.YSQTGNYELAVALSR.W "sp|P39656|OST48_HUMAN,tr|A0A0C4DGS1|A0A0C4DGS1_HUMAN" 2 1670.8264 1.2 17866 18613 2 1670.827858 836.4205 Dolichyl-diphosphooligosaccharide--protein glycosyltransferase 48 kDa subunit OS=Homo sapiens OX=9606 GN=DDOST PE=1 SV=4 6 3328.7 - 1.04E+06 - - - 0.8726 - 3.375 0.717 - 902.5 1 2 0 0.0015 15 0 0 0 2.29E+07 1.91E+07 - - - 7.3269 0.9999 221125_WJC_METTL3_EV_vs_WT_F02.18614.18614.2 8.02E-06 13/22 K.YNILGTNAIMDK.M "sp|Q9BUJ2|HNRL1_HUMAN,tr|M0QYZ0|M0QYZ0_HUMAN,tr|A0A0A0MRA5|A0A0A0MRA5_HUMAN,tr|M0R3F1|M0R3F1_HUMAN,tr|B7Z4B8|B7Z4B8_HUMAN" 5 1351.6806 1.53 17867 18614 2 1351.681958 676.8476 Heterogeneous nuclear ribonucleoprotein U-like protein 1 OS=Homo sapiens OX=9606 GN=HNRNPUL1 PE=1 SV=2 5.83 3328.8 - 880443 - - - 1.0143 - 2.552 0.541 - 381.6 1 2 0 0.0014 12 0 0 0 2.00E+08 1.31E+08 - - - 5.5015 0.9812 221125_WJC_METTL3_EV_vs_WT_F02.18620.18620.2 8.65E-06 22-Nov R.IEYVTVTPEGFR.Y sp|Q7KZ85|SPT6H_HUMAN 1 1409.7191 0.86 17871 18620 2 1409.709107 705.8668 Transcription elongation factor SPT6 OS=Homo sapiens OX=9606 GN=SUPT6H PE=1 SV=2 4.53 3329.5 - 1.32E+06 - - - -7.0752 - 2.31 0.352 - 353 1 2 0 -0.01 12 0 0 0 9.13E+06 1.06E+07 - - - 3.8407 0.9886 221125_WJC_METTL3_EV_vs_WT_F02.18621.18621.3 0.0282 Nov-60 R.VFLQGPAPVGTPSFNR[166.11].Q "sp|Q8IWZ3|ANKH1_HUMAN,tr|H0Y472|H0Y472_HUMAN,tr|H0Y4P6|H0Y4P6_HUMAN,tr|H7C0V5|H7C0V5_HUMAN,tr|H0Y785|H0Y785_HUMAN" 5 1695.8972 0.87 17872 18621 3 1695.902854 566.3063 Ankyrin repeat and KH domain-containing protein 1 OS=Homo sapiens OX=9606 GN=ANKHD1 PE=1 SV=1 9.72 3329.5 - 2.83E+06 - - - 3.328 - 1.943 0.222 - 108.5 1 2 0 0.0056 16 0 0 0 4.41E+07 5.06E+07 - - - 2.7179 0.9995 221125_WJC_METTL3_EV_vs_WT_F02.18625.18625.2 0.0406 14-Sep R.EAFLEQFR.K "sp|P23258|TBG1_HUMAN,tr|A0A7P0T9G6|A0A7P0T9G6_HUMAN" 2 1038.5134 0.79 17876 18625 2 1038.514118 520.264 Tubulin gamma-1 chain OS=Homo sapiens OX=9606 GN=TUBG1 PE=1 SV=2 4.53 3329.9 - 861297 - - - 0.648 - 1.605 0.378 - 267.4 1 2 0 0.0007 8 0 0 0 1.25E+07 1.58E+07 - - - 3.2596 0.9909 221125_WJC_METTL3_EV_vs_WT_F02.18626.18626.3 0.0388 Dec-48 R.LPPGFNDVDALC[160.03]R.A "sp|Q8IY67|RAVR1_HUMAN,tr|E9PAU2|E9PAU2_HUMAN,tr|A0A087WZ13|A0A087WZ13_HUMAN" 3 1472.7082 0.93 17877 18626 3 1472.712098 491.91 Ribonucleoprotein PTB-binding 1 OS=Homo sapiens OX=9606 GN=RAVER1 PE=1 SV=1 4.21 3330 - 526752 - - - 2.6475 - 1.796 0.217 - 192.1 1 2 0 0.0039 13 0 0 0 1.23E+07 1.33E+07 - - - 2.5459 0.9012 221125_WJC_METTL3_EV_vs_WT_F02.18627.18627.2 3.48 20-Jul K.NALESYAFNMK[136.11].S "sp|P0DMV8|HS71A_HUMAN,sp|P34931|HS71L_HUMAN,sp|P0DMV9|HS71B_HUMAN,tr|Q53FA3|Q53FA3_HUMAN,tr|V9GZ37|V9GZ37_HUMAN,tr|A0A0G2JIW1|A0A0G2JIW1_HUMAN" 6 1294.6107 1.12 17878 18627 2 1294.614196 648.3126 Heat shock 70 kDa protein 1A OS=Homo sapiens OX=9606 GN=HSPA1A PE=1 SV=1 6 3330.1 - 515042 - - - 2.6827 - 1.22 0.064 - 99.9 2 2 0 0.0035 11 0 0 0 8.34E+06 7.43E+06 - - - -0.0839 0.9999 221125_WJC_METTL3_EV_vs_WT_F02.18631.18631.3 0.000736 14/60 R.VFLQGPAPVGTPSFNR.Q "sp|Q8IWZ3|ANKH1_HUMAN,tr|H0Y472|H0Y472_HUMAN,tr|H0Y4P6|H0Y4P6_HUMAN,tr|H7C0V5|H7C0V5_HUMAN,tr|H0Y785|H0Y785_HUMAN" 5 1685.8889 0.87 17880 18631 3 1685.890887 562.9703 Ankyrin repeat and KH domain-containing protein 1 OS=Homo sapiens OX=9606 GN=ANKHD1 PE=1 SV=1 9.72 3330.6 - 3.00E+06 - - - 1.1549 - 2.192 0.413 - 158.3 1 2 0 0.0019 16 0 0 0 4.41E+07 5.06E+07 - - - 5.1577 0.9997 221125_WJC_METTL3_EV_vs_WT_F02.18635.18635.2 0.000693 18-Oct K.VGQISFDLPR[166.11].Q sp|Q9Y4W6|AFG32_HUMAN 1 1140.6167 1.89 17884 18635 2 1140.615722 571.3156 AFG3-like protein 2 OS=Homo sapiens OX=9606 GN=AFG3L2 PE=1 SV=2 5.81 3330.9 - 1.45E+06 - - - -0.8381 - 1.872 0.393 - 340.8 1 2 0 -0.001 10 0 0 0 5.24E+07 2.77E+07 - - - 3.6936 0.9949 221125_WJC_METTL3_EV_vs_WT_F02.18637.18637.3 0.00536 Nov-56 R.YSQTGNYELAVALSR.W "sp|P39656|OST48_HUMAN,tr|A0A0C4DGS1|A0A0C4DGS1_HUMAN" 2 1670.8264 0.93 17886 18637 3 1670.83091 557.9494 Dolichyl-diphosphooligosaccharide--protein glycosyltransferase 48 kDa subunit OS=Homo sapiens OX=9606 GN=DDOST PE=1 SV=4 6 3331.2 - 916447 - - - 2.6993 - 1.972 0.238 - 121.2 1 2 0 0.0045 15 0 0 0 8.81E+06 9.51E+06 - - - 2.9641 0.997 221125_WJC_METTL3_EV_vs_WT_F02.18639.18639.2 0.0127 20-Jul K.VTTQTSLPLFR[166.11].S "sp|Q13596|SNX1_HUMAN,tr|H0YK43|H0YK43_HUMAN" 2 1271.7113 1.11 17888 18639 2 1271.711129 636.8629 Sorting nexin-1 OS=Homo sapiens OX=9606 GN=SNX1 PE=1 SV=3 9.72 3331.4 - 742680 - - - -0.14 - 1.614 0.153 - 190.3 1 2 0 -0.0002 11 0 0 0 1.95E+07 1.76E+07 - - - 1.466 0.9842 221125_WJC_METTL3_EV_vs_WT_F02.18641.18641.3 0.391 Sep-36 K.IDTIEIITDR[166.11].Q "sp|P22626|ROA2_HUMAN,tr|A0A7I2YQN4|A0A7I2YQN4_HUMAN,tr|A0A7I2V4N0|A0A7I2V4N0_HUMAN,tr|A0A024RA28|A0A024RA28_HUMAN,tr|A0A7I2V4N1|A0A7I2V4N1_HUMAN,tr|A0A7I2V4I6|A0A7I2V4I6_HUMAN,tr|A0A087WUI2|A0A087WUI2_HUMAN,tr|A0A7I2V4S4|A0A7I2V4S4_HUMAN,tr|A0A7I2V323|A0A7I2V323_HUMAN,tr|A0A7I2V3P1|A0A7I2V3P1_HUMAN,tr|A0A7I2V3P7|A0A7I2V3P7_HUMAN" 11 1197.648 1.04 17890 18641 3 1197.650674 400.2233 Heterogeneous nuclear ribonucleoproteins A2\B1 OS=Homo sapiens OX=9606 GN=HNRNPA2B1 PE=1 SV=2 4.03 3331.7 - 503322 - - - 2.201 - 1.912 0.141 - 100.1 1 2 0 0.0026 10 0 0 0 8.52E+06 8.16E+06 - - - 2.0042 0.9999 221125_WJC_METTL3_EV_vs_WT_F02.18642.18642.2 8.68E-05 13/24 R.AIGDGEDEMLFTR[166.11].R "sp|O14654|IRS4_HUMAN,tr|A0A804CF45|A0A804CF45_HUMAN" 2 1462.6638 0.67 17891 18642 2 1462.663307 732.3392 Insulin receptor substrate 4 OS=Homo sapiens OX=9606 GN=IRS4 PE=1 SV=1 3.92 3331.8 - 316736 - - - -0.3131 - 2.153 0.486 - 492.2 1 2 0 -0.0005 13 0 0 0 4.19E+07 6.27E+07 - - - 4.5986 1 221125_WJC_METTL3_EV_vs_WT_F02.18645.18645.2 6.06E-05 13/22 K.YNILGTNAIMDK[136.11].M "sp|Q9BUJ2|HNRL1_HUMAN,tr|M0QYZ0|M0QYZ0_HUMAN,tr|A0A0A0MRA5|A0A0A0MRA5_HUMAN,tr|M0R3F1|M0R3F1_HUMAN,tr|B7Z4B8|B7Z4B8_HUMAN" 5 1359.6948 1.53 17892 18645 2 1359.696704 680.8547 Heterogeneous nuclear ribonucleoprotein U-like protein 1 OS=Homo sapiens OX=9606 GN=HNRNPUL1 PE=1 SV=2 5.83 3332.2 - 7.46E+06 - - - 1.4099 - 2.685 0.583 - 466.5 1 2 0 0.0019 12 0 0 0 2.00E+08 1.31E+08 - - - 5.9452 0.9998 221125_WJC_METTL3_EV_vs_WT_F02.18646.18646.2 0.000276 16-Aug R.IEYQFFEDR[166.11].H sp|Q9NYU2|UGGG1_HUMAN 1 1255.5749 0.07 17893 18646 2 1255.573906 628.7947 UDP-glucose:glycoprotein glucosyltransferase 1 OS=Homo sapiens OX=9606 GN=UGGT1 PE=1 SV=3 4.14 3332.2 - 3.08E+06 - - - -0.7702 - 1.934 0.481 - 348.7 1 2 0 -0.001 9 0 0 0 5.26E+06 7.09E+07 - - - 4.5016 1 221125_WJC_METTL3_EV_vs_WT_F02.18647.18647.2 7.56E-13 16/28 K.APGMNSLEQGMVGLK.L sp|Q9BYJ9|YTHD1_HUMAN 1 1530.7534 1.47 17894 18647 2 1530.754114 766.384 YTH domain-containing family protein 1 OS=Homo sapiens OX=9606 GN=YTHDF1 PE=1 SV=1 6.05 3332.3 - 2.63E+06 - - - 0.4442 - 3.488 0.667 - 913.8 1 2 0 0.0007 15 0 0 0 5.41E+07 3.69E+07 - - - 7.0388 0.9998 221125_WJC_METTL3_EV_vs_WT_F02.18648.18648.2 9.54E-05 14/28 R.LLDLPAAASSEDIER.S sp|P22466|GALA_HUMAN 1 1598.8152 2.86 17895 18648 2 1598.812186 800.4149 Galanin peptides OS=Homo sapiens OX=9606 GN=GAL PE=1 SV=3 3.92 3332.4 - 2.09E+06 - - - -1.8639 - 2.878 0.525 - 497.8 1 2 0 -0.003 15 0 0 0 6.15E+07 2.15E+07 - - - 5.5166 0.9998 221125_WJC_METTL3_EV_vs_WT_F02.18650.18650.2 5.47E-05 14/26 R.LGDAILSVNGTDLR[166.11].Q "sp|Q13425|SNTB2_HUMAN,tr|A0A140TA73|A0A140TA73_HUMAN,tr|J3KT21|J3KT21_HUMAN,tr|H0YCS0|H0YCS0_HUMAN,tr|A0A0G2JM75|A0A0G2JM75_HUMAN" 5 1452.7812 5.97 17897 18650 2 1452.780297 727.3979 Beta-2-syntrophin OS=Homo sapiens OX=9606 GN=SNTB2 PE=1 SV=1 4.21 3332.6 - 1.40E+06 - - - -0.6064 - 2.42 0.409 - 559.8 1 2 0 -0.0009 14 0 0 0 1.41E+08 2.35E+07 - - - 4.2794 1 221125_WJC_METTL3_EV_vs_WT_F02.18653.18653.2 2.86E-06 13/24 R.TLQYLSQGNVVFK.D "sp|P82663|RT25_HUMAN,tr|E7EPW2|E7EPW2_HUMAN" 2 1495.8035 0.33 17900 18653 2 1495.809858 748.909 "28S ribosomal protein S25, mitochondrial OS=Homo sapiens OX=9606 GN=MRPS25 PE=1 SV=1" 8.26 3332.9 - 579176 - - - 4.2646 - 2.616 0.575 - 566.1 1 2 0 0.0064 13 0 0 0 1.68E+07 5.12E+07 - - - 5.754 1 221125_WJC_METTL3_EV_vs_WT_F02.18656.18656.2 3.42E-10 28-Dec K.APGMNSLEQGMVGLK[136.11].L sp|Q9BYJ9|YTHD1_HUMAN 1 1538.7676 1.47 17901 18656 2 1538.76809 770.3911 YTH domain-containing family protein 1 OS=Homo sapiens OX=9606 GN=YTHDF1 PE=1 SV=1 6.05 3333.3 - 2.11E+06 - - - 0.2963 - 2.922 0.586 - 419.4 1 2 0 0.0005 15 0 0 0 5.41E+07 3.69E+07 - - - 6.0053 0.997 221125_WJC_METTL3_EV_vs_WT_F02.18658.18658.2 0.0759 20-Oct R.DILLC[160.03]TDIASR[166.11].G sp|Q9NUL7|DDX28_HUMAN 1 1285.6576 0.26 17903 18658 2 1285.662112 643.8361 Probable ATP-dependent RNA helicase DDX28 OS=Homo sapiens OX=9606 GN=DDX28 PE=1 SV=2 4.21 3333.5 - 3.20E+06 - - - 3.5429 - 1.897 0.323 - 438 1 2 0 0.0046 11 0 0 0 1.75E+07 6.71E+07 - - - 3.1573 0.9981 221125_WJC_METTL3_EV_vs_WT_F02.18659.18659.2 5.74E-06 24-Dec R.AIGDGEDEMLFTR.R "sp|O14654|IRS4_HUMAN,tr|A0A804CF45|A0A804CF45_HUMAN" 2 1452.6555 0.67 17904 18659 2 1452.663044 727.335 Insulin receptor substrate 4 OS=Homo sapiens OX=9606 GN=IRS4 PE=1 SV=1 3.92 3333.6 - 1.29E+06 - - - 5.1967 - 2.306 0.613 - 396.3 1 2 0 0.0076 13 0 0 0 4.19E+07 6.27E+07 - - - 5.7106 0.9997 221125_WJC_METTL3_EV_vs_WT_F02.18660.18660.2 3.36E-06 26-Dec K.LTPITYPQGLAMAK[136.11].E sp|P63000|RAC1_HUMAN 1 1510.8309 1.19 17905 18660 2 1510.833571 756.4227 Ras-related C3 botulinum toxin substrate 1 OS=Homo sapiens OX=9606 GN=RAC1 PE=1 SV=1 8.59 3333.7 - 1.15E+06 - - - 1.7765 - 2.196 0.51 - 291.1 1 2 0 0.0027 14 0 0 0 6.00E+07 5.05E+07 - - - 4.781 0.9998 221125_WJC_METTL3_EV_vs_WT_F02.18661.18661.2 0.0172 20-Nov R.VLALSFDAPGR.L "sp|Q9H1Z4|WDR13_HUMAN,tr|A0A087X091|A0A087X091_HUMAN" 2 1144.6241 0.18 17906 18661 2 1144.625475 573.3193 WD repeat-containing protein 13 OS=Homo sapiens OX=9606 GN=WDR13 PE=1 SV=2 5.81 3333.8 - 818248 - - - 1.238 - 2.371 0.422 - 432 1 2 0 0.0014 11 0 0 0 4.78E+07 2.72E+08 - - - 4.4929 0.9996 221125_WJC_METTL3_EV_vs_WT_F02.18665.18665.2 0.00635 20-Aug R.VESLLVTAISK[136.11].A sp|O43143|DHX15_HUMAN 1 1166.7002 0.97 17908 18665 2 1166.701366 584.3574 Pre-mRNA-splicing factor ATP-dependent RNA helicase DHX15 OS=Homo sapiens OX=9606 GN=DHX15 PE=1 SV=2 5.97 3334.2 - 2.17E+06 - - - 1.008 - 1.845 0.386 - 155.4 1 2 0 0.0012 11 0 0 0 4.25E+07 4.39E+07 - - - 3.5485 0.9969 221125_WJC_METTL3_EV_vs_WT_F02.18668.18668.2 0.387 14-Sep K.AGISFIIK[136.11].R "sp|P78347|GTF2I_HUMAN,tr|A0A494C1K3|A0A494C1K3_HUMAN" 2 855.5309 1.29 17911 18668 2 855.531158 428.7727 General transcription factor II-I OS=Homo sapiens OX=9606 GN=GTF2I PE=1 SV=2 8.8 3334.5 - 1.30E+06 - - - 0.2548 - 1.53 0.156 - 191 1 2 0 0.0002 8 0 0 0 5.89E+07 4.56E+07 - - - 1.4757 0.9994 221125_WJC_METTL3_EV_vs_WT_F02.18669.18669.2 0.00349 20-Sep R.DILLC[160.03]TDIASR.G sp|Q9NUL7|DDX28_HUMAN 1 1275.6493 0.26 17912 18669 2 1275.651833 638.8319 Probable ATP-dependent RNA helicase DDX28 OS=Homo sapiens OX=9606 GN=DDX28 PE=1 SV=2 4.21 3334.5 - 1.01E+06 - - - 1.9958 - 1.991 0.393 - 335.8 1 2 0 0.0025 11 0 0 0 1.81E+07 6.91E+07 - - - 3.8058 0.9996 221125_WJC_METTL3_EV_vs_WT_F02.18671.18671.3 4.53E-06 Dec-48 R.IR[166.11]PLPEEMLSYAR[166.11].D sp|Q01780|EXOSX_HUMAN 1 1593.8452 3.27 17914 18671 3 1593.85178 532.289 Exosome component 10 OS=Homo sapiens OX=9606 GN=EXOSC10 PE=1 SV=2 6.14 3334.7 - 928796 - - - 4.1359 - 2.561 0.455 - 228.7 1 2 0 0.0066 13 0 0 0 3.91E+07 1.20E+07 - - - 6.1607 0.9989 221125_WJC_METTL3_EV_vs_WT_F02.18673.18673.3 0.0018 Nov-36 K.IR[166.11]EDPLFIIR[166.11].K sp|Q9NXE8|CWC25_HUMAN 1 1290.7563 1.15 17916 18673 3 1290.754105 431.2594 Pre-mRNA-splicing factor CWC25 homolog OS=Homo sapiens OX=9606 GN=CWC25 PE=1 SV=1 6.07 3335 - 353273 - - - -1.6982 - 2.322 0.338 - 239 1 2 1 -0.0022 10 0 0 0 7.30E+06 6.36E+06 - - - 4.768 0.9999 221125_WJC_METTL3_EV_vs_WT_F02.18674.18674.3 1.18E-05 14/56 R.SDGALLLGASSLSGR.C sp|Q9BQA1|MEP50_HUMAN 1 1402.7416 2.44 17917 18674 3 1402.740612 468.5878 Methylosome protein 50 OS=Homo sapiens OX=9606 GN=WDR77 PE=1 SV=1 5.55 3335.1 - 334812 - - - -0.7093 - 2.628 0.433 - 281.5 1 2 0 -0.001 15 0 0 0 3.85E+07 1.58E+07 - - - 5.8885 0.9929 221125_WJC_METTL3_EV_vs_WT_F02.18678.18678.2 0.563 18-Aug K.YNLQLNPEWR.M "sp|Q9NWS0|PIHD1_HUMAN,tr|M0QYF4|M0QYF4_HUMAN,tr|M0QXD5|M0QXD5_HUMAN,tr|M0R3A4|M0R3A4_HUMAN,tr|M0R2P8|M0R2P8_HUMAN,tr|M0QYA2|M0QYA2_HUMAN" 6 1331.6622 1.24 17919 18678 2 1331.664635 666.8384 PIH1 domain-containing protein 1 OS=Homo sapiens OX=9606 GN=PIH1D1 PE=1 SV=1 6 3335.6 - 1.85E+06 - - - 1.8023 - 1.808 0.12 - 126 3 2 0 0.0024 10 0 0 0 4.49E+07 3.63E+07 - - - 1.3665 1 221125_WJC_METTL3_EV_vs_WT_F02.18680.18680.2 3.56E-07 17/28 R.SDGALLLGASSLSGR[166.11].C sp|Q9BQA1|MEP50_HUMAN 1 1412.7499 2.85 17921 18680 2 1412.75064 707.3822 Methylosome protein 50 OS=Homo sapiens OX=9606 GN=WDR77 PE=1 SV=1 5.55 3335.7 - 4.61E+06 - - - 0.5401 - 3.442 0.545 - 931.6 1 2 0 0.0008 15 0 0 0 5.05E+08 1.77E+08 - - - 6.105 0.9868 221125_WJC_METTL3_EV_vs_WT_F02.18682.18682.2 3.28 14-Sep R.DILLQGLK[136.11].A "sp|Q99986|VRK1_HUMAN,tr|A0A7P0T838|A0A7P0T838_HUMAN,tr|H0YJJ9|H0YJJ9_HUMAN,tr|A0A7P0TA16|A0A7P0TA16_HUMAN,tr|A0A7P0T8N0|A0A7P0T8N0_HUMAN,tr|H0YJF7|H0YJF7_HUMAN,tr|A0A7P0T9T1|A0A7P0T9T1_HUMAN,tr|A0A7P0Z445|A0A7P0Z445_HUMAN,tr|A0A7P0TAA6|A0A7P0TAA6_HUMAN,tr|A0A7P0T9E5|A0A7P0T9E5_HUMAN,tr|A0A7P0TBB8|A0A7P0TBB8_HUMAN,tr|A0A7P0Z462|A0A7P0Z462_HUMAN,tr|A0A7P0TBE4|A0A7P0TBE4_HUMAN,tr|A0A7P0T925|A0A7P0T925_HUMAN,tr|H0YJ50|H0YJ50_HUMAN,tr|A0A7P0TA65|A0A7P0TA65_HUMAN,tr|A0A7P0T824|A0A7P0T824_HUMAN,tr|A0A7P0T9I1|A0A7P0T9I1_HUMAN,tr|A0A7P0T977|A0A7P0T977_HUMAN,tr|A0A7P0Z3Z7|A0A7P0Z3Z7_HUMAN,tr|A0A7P0TAS8|A0A7P0TAS8_HUMAN,tr|A0A7P0TB15|A0A7P0TB15_HUMAN,tr|A0A7P0T952|A0A7P0T952_HUMAN" 23 906.563 0.37 17923 18682 2 906.565261 454.2888 Serine\threonine-protein kinase VRK1 OS=Homo sapiens OX=9606 GN=VRK1 PE=1 SV=1 5.84 3336 - 672468 - - - 2.5293 - 1.614 0.105 - 255 1 2 0 0.0023 8 0 0 0 1.80E+06 4.92E+06 - - - 1.2596 0.9998 221125_WJC_METTL3_EV_vs_WT_F02.18690.18690.2 9.88E-06 22-Nov R.LNVGGTVFLTTR.Q "sp|Q8N5Z5|KCD17_HUMAN,tr|A0A087WX35|A0A087WX35_HUMAN" 2 1276.7139 3.92 17929 18690 2 1276.71598 639.3642 BTB\POZ domain-containing protein KCTD17 OS=Homo sapiens OX=9606 GN=KCTD17 PE=1 SV=3 9.75 3336.8 - 1.90E+06 - - - 1.601 - 2.126 0.499 - 379.2 1 2 0 0.002 12 0 0 0 6.05E+08 1.54E+08 - - - 4.7105 0.9945 221125_WJC_METTL3_EV_vs_WT_F02.18692.18692.2 9.84E-07 17/28 R.LLDLPAAASSEDIER[166.11].S sp|P22466|GALA_HUMAN 1 1608.8234 2.85 17931 18692 2 1609.82425 805.419 Galanin peptides OS=Homo sapiens OX=9606 GN=GAL PE=1 SV=3 3.92 3337 - 1.54E+06 - - - 622.0782 - 3.051 0.568 - 768.6 1 2 0 1.0008 15 0 0 0 6.14E+07 2.15E+07 - - - 5.6644 0.9998 221125_WJC_METTL3_EV_vs_WT_F02.18694.18694.2 2.08E-05 14-Sep K.LMNLWTER.F "sp|P52732|KIF11_HUMAN,tr|A0A7I2V3A9|A0A7I2V3A9_HUMAN" 2 1061.5328 0.27 17933 18694 2 1061.533427 531.7737 Kinesin-like protein KIF11 OS=Homo sapiens OX=9606 GN=KIF11 PE=1 SV=2 6 3337.2 - 1.09E+06 - - - 0.5897 - 1.924 0.42 - 323.2 1 2 0 0.0006 8 0 0 0 1.91E+07 7.19E+07 - - - 4.1166 0.9999 221125_WJC_METTL3_EV_vs_WT_F02.18695.18695.2 2.11E-05 18-Oct K.YNLQLNPEWR[166.11].M "sp|Q9NWS0|PIHD1_HUMAN,tr|M0QYF4|M0QYF4_HUMAN,tr|M0QXD5|M0QXD5_HUMAN,tr|M0R3A4|M0R3A4_HUMAN,tr|M0R2P8|M0R2P8_HUMAN,tr|M0QYA2|M0QYA2_HUMAN" 6 1341.6705 1.23 17934 18695 2 1341.669537 671.8425 PIH1 domain-containing protein 1 OS=Homo sapiens OX=9606 GN=PIH1D1 PE=1 SV=1 6 3337.3 - 1.03E+06 - - - -0.7215 - 2.278 0.509 - 447.6 1 2 0 -0.001 10 0 0 0 4.46E+07 3.63E+07 - - - 5.0982 0.989 221125_WJC_METTL3_EV_vs_WT_F02.18698.18698.2 0.0678 12-Jun R.DGFGFIK[136.11].C "sp|O75534|CSDE1_HUMAN,tr|E9PLT0|E9PLT0_HUMAN" 2 790.4105 0.64 17937 18698 2 790.410966 396.2125 Cold shock domain-containing protein E1 OS=Homo sapiens OX=9606 GN=CSDE1 PE=1 SV=2 5.84 3337.6 - 510007 - - - 0.6022 - 1.067 0.188 - 104.5 1 2 0 0.0005 7 0 0 0 7.53E+06 1.18E+07 - - - 0.6349 0.9753 221125_WJC_METTL3_EV_vs_WT_F02.18700.18700.2 0.0107 16-Sep F.ADALLIIPK[136.11].V "sp|Q92526|TCPW_HUMAN,sp|P40227|TCPZ_HUMAN" 2 960.6099 0.47 17939 18700 2 960.610469 481.3122 T-complex protein 1 subunit zeta-2 OS=Homo sapiens OX=9606 GN=CCT6B PE=1 SV=5 5.88 3337.9 - 489967 - - - 0.5736 - 1.798 0.349 - 213.2 1 1 0 0.0006 9 0 0 0 1.93E+06 4.08E+06 - - - 3.3158 0.9999 221125_WJC_METTL3_EV_vs_WT_F02.18702.18702.2 3.28E-05 18-Oct R.QAFAPFGPIK.S "sp|Q9UHX1|PUF60_HUMAN,tr|A0A0J9YYL3|A0A0J9YYL3_HUMAN,tr|A0A0J9YWM1|A0A0J9YWM1_HUMAN,tr|H0YEM1|H0YEM1_HUMAN,tr|E9PMU7|E9PMU7_HUMAN,tr|E9PN18|E9PN18_HUMAN,tr|E9PL19|E9PL19_HUMAN,tr|A0A0J9YVR6|A0A0J9YVR6_HUMAN,tr|A0A0J9YXX5|A0A0J9YXX5_HUMAN,tr|A0A0J9YXJ8|A0A0J9YXJ8_HUMAN,tr|E9PQ56|E9PQ56_HUMAN,tr|H0YCP8|H0YCP8_HUMAN,tr|A0A0J9YVP6|A0A0J9YVP6_HUMAN" 13 1074.5862 1.22 17940 18702 2 1074.587425 538.3004 Poly(U)-binding-splicing factor PUF60 OS=Homo sapiens OX=9606 GN=PUF60 PE=1 SV=1 8.75 3338.1 - 4.93E+06 - - - 1.1251 - 2.005 0.563 - 332.1 1 2 0 0.0012 10 0 0 0 1.28E+08 1.05E+08 - - - 5.1407 0.9957 221125_WJC_METTL3_EV_vs_WT_F02.18705.18705.2 0.84 14-Sep K.AGISFIIK.R "sp|P78347|GTF2I_HUMAN,tr|A0A494C1K3|A0A494C1K3_HUMAN" 2 847.5167 1.29 17943 18705 2 847.517624 424.7656 General transcription factor II-I OS=Homo sapiens OX=9606 GN=GTF2I PE=1 SV=2 8.8 3338.2 - 8.07E+06 - - - 1.043 - 1.461 0.168 - 197 1 2 0 0.0009 8 0 0 0 5.88E+07 4.56E+07 - - - 1.425 1 221125_WJC_METTL3_EV_vs_WT_F02.18706.18706.2 8.88E-05 16/30 R.LLDLPAAASSEDIERS.- sp|P22466|GALA_HUMAN 1 1685.8472 3.64 17944 18706 2 1685.845712 843.9309 Galanin peptides OS=Homo sapiens OX=9606 GN=GAL PE=1 SV=3 3.92 3338.3 - 1.57E+06 - - - -0.8797 - 3.001 0.617 - 657.6 1 2 0 -0.0015 16 0 0 0 1.70E+07 4.65E+06 - - - 6.2995 0.9995 221125_WJC_METTL3_EV_vs_WT_F02.18707.18707.3 1.40E-05 14/48 R.KIEEIKDFLLTAR.R "sp|P63173|RL38_HUMAN,tr|J3KT73|J3KT73_HUMAN,tr|J3QL01|J3QL01_HUMAN,tr|J3KSP2|J3KSP2_HUMAN" 4 1574.9032 1 17945 18707 3 1574.901955 525.975 60S ribosomal protein L38 OS=Homo sapiens OX=9606 GN=RPL38 PE=1 SV=2 6.18 3338.4 - 1.44E+06 - - - -0.7867 - 2.341 0.375 - 328.9 1 2 1 -0.0012 13 0 0 0 7.35E+06 7.34E+06 - - - 5.0267 0.9997 221125_WJC_METTL3_EV_vs_WT_F02.18708.18708.3 4.78E-06 15/48 R.K[136.11]IEEIK[136.11]DFLLTAR[166.11].R "sp|P63173|RL38_HUMAN,tr|J3KT73|J3KT73_HUMAN,tr|J3QL01|J3QL01_HUMAN,tr|J3KSP2|J3KSP2_HUMAN" 4 1600.9399 1 17946 18708 3 1600.942466 534.6539 60S ribosomal protein L38 OS=Homo sapiens OX=9606 GN=RPL38 PE=1 SV=2 6.18 3338.5 - 1.50E+06 - - - 1.6259 - 2.589 0.458 - 336.4 1 2 1 0.0026 13 0 0 0 7.35E+06 7.34E+06 - - - 6.2247 0.9995 221125_WJC_METTL3_EV_vs_WT_F02.18710.18710.2 0.00192 16-Sep K.ATEMLIFGK[136.11].K "sp|O75521|ECI2_HUMAN,tr|A0A0C4DGA2|A0A0C4DGA2_HUMAN" 2 1016.5456 1.85 17948 18710 2 1016.547533 509.2801 Enoyl-CoA delta isomerase 2 OS=Homo sapiens OX=9606 GN=ECI2 PE=1 SV=4 6.05 3338.6 - 812829 - - - 1.8976 - 1.718 0.443 - 275.2 1 2 0 0.0019 9 0 0 0 1.71E+07 9.22E+06 - - - 3.878 0.9993 221125_WJC_METTL3_EV_vs_WT_F02.18711.18711.2 0.000373 14-Sep K.MVGFIIGR.G "sp|Q96I24|FUBP3_HUMAN,sp|Q96AE4|FUBP1_HUMAN,tr|E9PEB5|E9PEB5_HUMAN,tr|C9JSZ1|C9JSZ1_HUMAN" 4 891.5 3.25 17949 18711 2 891.502432 446.7573 Far upstream element-binding protein 3 OS=Homo sapiens OX=9606 GN=FUBP3 PE=1 SV=2 9.5 3338.8 - 693254 - - - 2.6786 - 1.797 0.462 - 307.8 1 2 0 0.0024 8 0 0 0 1.03E+07 3.18E+06 - - - 4.2203 0.8774 221125_WJC_METTL3_EV_vs_WT_F02.18712.18712.3 2.01 Oct-56 R.FLTAVNLEHPEMLEK.A "sp|Q9Y2Q3|GSTK1_HUMAN,tr|E9PFN5|E9PFN5_HUMAN,tr|C9JNT3|C9JNT3_HUMAN" 3 1769.9022 1.9 17950 18712 3 1769.901167 590.9747 Glutathione S-transferase kappa 1 OS=Homo sapiens OX=9606 GN=GSTK1 PE=1 SV=3 4.75 3338.9 - 589536 - - - -0.5876 - 1.596 0.063 - 61.7 2 2 0 -0.001 15 0 0 0 4.51E+06 2.38E+06 - - - 0.3227 1 221125_WJC_METTL3_EV_vs_WT_F02.18713.18713.2 3.59E-10 15/30 K.TTLQVDTLNAELAAER.S sp|P35580|MYH10_HUMAN 1 1743.9003 0.92 17951 18713 2 1743.901681 872.9574 Myosin-10 OS=Homo sapiens OX=9606 GN=MYH10 PE=1 SV=3 4.14 3339 - 549773 - - - 0.7959 - 3.402 0.519 - 645.4 1 2 0 0.0014 16 0 0 0 2.01E+07 2.19E+07 - - - 5.8841 1 221125_WJC_METTL3_EV_vs_WT_F02.18714.18714.2 9.38E-08 17/30 K.TTLQVDTLNAELAAER[166.11].S sp|P35580|MYH10_HUMAN 1 1753.9086 0.92 17952 18714 2 1753.912396 877.9616 Myosin-10 OS=Homo sapiens OX=9606 GN=MYH10 PE=1 SV=3 4.14 3339.2 - 541426 - - - 2.1854 - 3.756 0.584 - 1068.9 1 2 0 0.0038 16 0 0 0 2.01E+07 2.19E+07 - - - 6.6067 1 221125_WJC_METTL3_EV_vs_WT_F02.18716.18716.2 6.35E-07 13/28 R.VIGVELC[160.03]PEAVEDAR[166.11].V "sp|Q8IZ69|TRM2A_HUMAN,tr|F2Z2W7|F2Z2W7_HUMAN,tr|H7C100|H7C100_HUMAN" 3 1665.8271 0.22 17954 18716 2 1665.833513 833.9208 tRNA (uracil-5-)-methyltransferase homolog A OS=Homo sapiens OX=9606 GN=TRMT2A PE=1 SV=2 4 3339.4 - 308156 - - - 3.8245 - 2.737 0.584 - 523.1 1 2 0 0.0064 15 0 0 0 1.42E+06 6.36E+06 - - - 5.8278 0.9993 221125_WJC_METTL3_EV_vs_WT_F02.18719.18719.2 4.13E-05 30-Nov K.LGLPPLTPEQQEALQK[136.11].A "sp|Q9UHX1|PUF60_HUMAN,tr|A0A0J9YYL3|A0A0J9YYL3_HUMAN,tr|A0A0J9YWM1|A0A0J9YWM1_HUMAN,tr|H0YEM1|H0YEM1_HUMAN,tr|E9PMU7|E9PMU7_HUMAN,tr|E9PN18|E9PN18_HUMAN,tr|E9PL19|E9PL19_HUMAN,tr|A0A0J9YVR6|A0A0J9YVR6_HUMAN,tr|A0A0J9YXX5|A0A0J9YXX5_HUMAN,tr|A0A0J9YXJ8|A0A0J9YXJ8_HUMAN,tr|E9PQ56|E9PQ56_HUMAN,tr|A0A0J9YVP6|A0A0J9YVP6_HUMAN" 12 1768.9814 1.41 17956 18719 2 1768.986003 885.498 Poly(U)-binding-splicing factor PUF60 OS=Homo sapiens OX=9606 GN=PUF60 PE=1 SV=1 4.53 3339.8 - 372211 - - - 2.5738 - 1.979 0.451 - 175.7 1 2 0 0.0046 16 0 0 0 1.51E+07 1.07E+07 - - - 4.0488 0.9999 221125_WJC_METTL3_EV_vs_WT_F02.18721.18721.3 9.33E-06 16/56 R.SDGALLLGASSLSGR[166.11].C sp|Q9BQA1|MEP50_HUMAN 1 1412.7499 2.44 17958 18721 3 1412.75116 471.9239 Methylosome protein 50 OS=Homo sapiens OX=9606 GN=WDR77 PE=1 SV=1 5.55 3339.9 - 2.14E+06 - - - 0.9082 - 2.531 0.432 - 292.6 1 2 0 0.0013 15 0 0 0 3.85E+07 1.58E+07 - - - 5.7791 0.9999 221125_WJC_METTL3_EV_vs_WT_F02.18724.18724.2 6.61E-06 13/24 K.NLLFNDNTEC[160.03]LAR.L "sp|P02788|TRFL_HUMAN,tr|E7EQB2|E7EQB2_HUMAN,tr|E7ER44|E7ER44_HUMAN" 3 1578.746 41.92 17961 18724 2 1578.748187 790.3803 Lactotransferrin OS=Homo sapiens OX=9606 GN=LTF PE=1 SV=6 4.37 3340.2 - 1.14E+06 - - - 1.3593 - 2.458 0.58 - 548.6 1 2 0 0.0021 13 0 0 0 9.67E+06 2.31E+05 - - - 5.6324 0.9833 221125_WJC_METTL3_EV_vs_WT_F02.18726.18726.2 0.124 12-May K.EFSDIFR.R "sp|P46459|NSF_HUMAN,tr|I3L0N3|I3L0N3_HUMAN" 2 912.4341 1.4 17963 18726 2 912.433063 457.2243 Vesicle-fusing ATPase OS=Homo sapiens OX=9606 GN=NSF PE=1 SV=3 4.37 3340.5 - 682801 - - - -1.1716 - 1.321 0.071 - 105.3 1 2 0 -0.0011 7 0 0 0 4.48E+06 3.21E+06 - - - 0.4472 0.9682 221125_WJC_METTL3_EV_vs_WT_F02.18727.18727.2 4.84E-05 16/30 R.LLDLPAAASSEDIER[166.11]S.- sp|P22466|GALA_HUMAN 1 1695.8555 3.64 17964 18727 2 1696.852283 848.935 Galanin peptides OS=Homo sapiens OX=9606 GN=GAL PE=1 SV=3 3.92 3340.6 - 677805 - - - 587.7966 - 2.725 0.559 - 579.1 1 2 0 0.9968 16 0 0 0 1.70E+07 4.65E+06 - - - 5.3214 0.9997 221125_WJC_METTL3_EV_vs_WT_F02.18728.18728.2 0.000398 14-Sep K.MVGFIIGR[166.11].G "sp|Q96I24|FUBP3_HUMAN,sp|Q96AE4|FUBP1_HUMAN,tr|E9PEB5|E9PEB5_HUMAN,tr|C9JSZ1|C9JSZ1_HUMAN" 4 901.5083 3.15 17965 18728 2 901.50782 451.7614 Far upstream element-binding protein 3 OS=Homo sapiens OX=9606 GN=FUBP3 PE=1 SV=2 9.5 3340.7 - 450748 - - - -0.548 - 1.554 0.466 - 293.1 1 2 0 -0.0005 8 0 0 0 1.00E+07 3.18E+06 - - - 3.8123 0.9951 221125_WJC_METTL3_EV_vs_WT_F02.18729.18729.2 2.48 28-Sep K.VPSFETAEGIGTELK[136.11].A "sp|Q6PML9|ZNT9_HUMAN,tr|D6R9M6|D6R9M6_HUMAN" 2 1584.8127 0.42 17966 18729 2 1584.81144 793.4136 Zinc transporter 9 OS=Homo sapiens OX=9606 GN=SLC30A9 PE=1 SV=1 4.25 3340.8 - 263124 - - - -0.766 - 1.647 0.124 - 112.7 1 2 0 -0.0012 15 0 0 0 1.73E+06 4.09E+06 - - - 1.1832 0.9996 221125_WJC_METTL3_EV_vs_WT_F02.18731.18731.2 0.00159 Sep-36 R.ILSAENIPNLPPGGGLAGK.R "sp|O75688|PPM1B_HUMAN,tr|B8ZZF0|B8ZZF0_HUMAN,tr|A0A3B3IS24|A0A3B3IS24_HUMAN,tr|C9JIR6|C9JIR6_HUMAN" 4 1817.0047 999 17968 18731 2 1817.006848 909.5096 Protein phosphatase 1B OS=Homo sapiens OX=9606 GN=PPM1B PE=1 SV=1 6 3341.1 - 212738 - - - 1.1827 - 1.59 0.481 - 133.6 1 2 0 0.0021 19 0 0 0 3.79E+06 0.00E+00 - - - 3.7331 0.9996 221125_WJC_METTL3_EV_vs_WT_F02.18735.18735.2 0.000325 16-Sep K.NVTLPAVFK.A "sp|P36578|RL4_HUMAN,tr|H3BTP7|H3BTP7_HUMAN,tr|H3BU31|H3BU31_HUMAN" 3 987.5753 0.83 17971 18735 2 987.575893 494.7949 60S ribosomal protein L4 OS=Homo sapiens OX=9606 GN=RPL4 PE=1 SV=5 8.75 3341.5 - 5.65E+06 - - - 0.5832 - 1.781 0.365 - 251.3 1 2 0 0.0006 9 0 0 0 7.91E+07 9.57E+07 - - - 3.4065 0.9999 221125_WJC_METTL3_EV_vs_WT_F02.18738.18738.3 0.0018 15/60 K.TTLQVDTLNAELAAER[166.11].S sp|P35580|MYH10_HUMAN 1 1753.9086 1.7 17974 18738 3 1753.910152 585.6435 Myosin-10 OS=Homo sapiens OX=9606 GN=MYH10 PE=1 SV=3 4.14 3341.6 - 2.65E+06 - - - 0.906 - 2.489 0.368 - 356 1 2 0 0.0016 16 0 0 0 2.65E+07 1.56E+07 - - - 4.9822 0.9998 221125_WJC_METTL3_EV_vs_WT_F02.18739.18739.2 0.000972 16-Sep K.ATEMLIFGK.K "sp|O75521|ECI2_HUMAN,tr|A0A0C4DGA2|A0A0C4DGA2_HUMAN" 2 1008.5314 1.9 17975 18739 2 1008.532151 505.273 Enoyl-CoA delta isomerase 2 OS=Homo sapiens OX=9606 GN=ECI2 PE=1 SV=4 6.05 3341.7 - 2.53E+06 - - - 0.7407 - 1.902 0.432 - 363.1 1 2 0 0.0007 9 0 0 0 1.75E+07 9.22E+06 - - - 4.0915 1 221125_WJC_METTL3_EV_vs_WT_F02.18740.18740.3 9.51E-07 17/60 K.TTLQVDTLNAELAAER.S sp|P35580|MYH10_HUMAN 1 1743.9003 1.76 17976 18740 3 1743.902575 582.3074 Myosin-10 OS=Homo sapiens OX=9606 GN=MYH10 PE=1 SV=3 4.14 3341.7 - 2.29E+06 - - - 1.3086 - 2.881 0.446 - 408.8 1 2 0 0.0023 16 0 0 0 2.75E+07 1.56E+07 - - - 6.2269 0.9914 221125_WJC_METTL3_EV_vs_WT_F02.18741.18741.2 0.48 16-Jun R.GLVGEIIK[136.11]R[166.11].F "sp|P15531|NDKA_HUMAN,sp|P22392|NDKB_HUMAN,tr|Q32Q12|Q32Q12_HUMAN,tr|Q32Q12|Q32Q12_HUMAN,tr|J3KPD9|J3KPD9_HUMAN,tr|F6XY72|F6XY72_HUMAN,tr|E5RHP0|E5RHP0_HUMAN,tr|E7ERL0|E7ERL0_HUMAN,tr|C9K028|C9K028_HUMAN" 9 1001.6352 1.39 17977 18741 2 1001.636225 501.8249 Nucleoside diphosphate kinase A OS=Homo sapiens OX=9606 GN=NME1 PE=1 SV=1 8.75 3341.8 - 2.22E+06 - - - 0.9884 - 1.35 0.165 - 81.1 3 2 0 0.001 9 0 0 0 1.78E+07 1.27E+07 - - - 0.9145 0.9957 221125_WJC_METTL3_EV_vs_WT_F02.18742.18742.2 0.57 14-Jul K.EFTLEFSR.D "sp|P16615|AT2A2_HUMAN,sp|Q93084|AT2A3_HUMAN,sp|O14983|AT2A1_HUMAN,tr|H7C5W9|H7C5W9_HUMAN" 4 1027.4975 1.78 17978 18742 2 1027.497247 514.756 Sarcoplasmic\endoplasmic reticulum calcium ATPase 2 OS=Homo sapiens OX=9606 GN=ATP2A2 PE=1 SV=1 4.53 3341.9 - 1.94E+06 - - - -0.2083 - 1.479 0.133 - 267 1 2 0 -0.0002 8 0 0 0 3.23E+07 1.82E+07 - - - 1.2036 0.9995 221125_WJC_METTL3_EV_vs_WT_F02.18744.18744.2 0.000408 18-Oct R.DPAITSILEK.M "sp|Q9UI42|CBPA4_HUMAN,tr|B7Z5J4|B7Z5J4_HUMAN" 2 1085.5968 11.8 17980 18744 2 1085.598178 543.8057 Carboxypeptidase A4 OS=Homo sapiens OX=9606 GN=CPA4 PE=1 SV=2 4.37 3342 - 1.72E+06 - - - 1.2316 - 2.137 0.319 - 456.6 1 2 0 0.0013 10 0 0 0 4.14E+07 3.51E+06 - - - 3.5164 0.9999 221125_WJC_METTL3_EV_vs_WT_F02.18745.18745.2 5.55E-06 22-Nov K.ILLNAC[160.03]C[160.03]PGWVR.T sp|P16152|CBR1_HUMAN 1 1457.7272 1.63 17981 18745 2 1457.727668 729.8709 Carbonyl reductase [NADPH] 1 OS=Homo sapiens OX=9606 GN=CBR1 PE=1 SV=3 8.07 3342.1 - 1.68E+06 - - - 0.3478 - 2.195 0.514 - 440 1 2 0 0.0005 12 0 0 0 2.20E+07 1.35E+07 - - - 4.9058 0.9999 221125_WJC_METTL3_EV_vs_WT_F02.18746.18746.2 1.45E-05 14/24 K.ILTINEDGSLGLK[136.11].T sp|Q9UQR1|ZN148_HUMAN 1 1379.7751 0.17 17982 18746 2 1379.774223 690.8948 Zinc finger protein 148 OS=Homo sapiens OX=9606 GN=ZNF148 PE=1 SV=2 4.37 3342.2 - 1.27E+06 - - - -0.6689 - 2.64 0.496 - 651.4 1 2 0 -0.0009 13 0 0 0 2.75E+06 1.60E+07 - - - 5.1957 1 221125_WJC_METTL3_EV_vs_WT_F02.18751.18751.2 0.000597 14/28 R.SDGALLLGASSLSGR.C sp|Q9BQA1|MEP50_HUMAN 1 1402.7416 2.85 17986 18751 2 1402.742675 702.3781 Methylosome protein 50 OS=Homo sapiens OX=9606 GN=WDR77 PE=1 SV=1 5.55 3342.8 - 5.29E+07 - - - 0.7614 - 2.812 0.562 - 544.5 1 2 0 0.0011 15 0 0 0 5.04E+08 1.77E+08 - - - 5.7335 0.9997 221125_WJC_METTL3_EV_vs_WT_F02.18752.18752.2 0.00393 16-Sep R.ELLTEFGYK.G sp|P49411|EFTU_HUMAN 1 1098.5597 1.73 17987 18752 2 1098.559391 550.2871 "Elongation factor Tu, mitochondrial OS=Homo sapiens OX=9606 GN=TUFM PE=1 SV=2" 4.53 3342.9 - 955300 - - - -0.3059 - 1.681 0.4 - 240 1 2 0 -0.0003 9 0 0 0 3.10E+07 1.80E+07 - - - 3.4979 0.9998 221125_WJC_METTL3_EV_vs_WT_F02.18753.18753.2 6.94E-05 18-Nov K.DGVGMVEYLR.K "sp|Q13242|SRSF9_HUMAN,tr|H0YIB4|H0YIB4_HUMAN" 2 1137.5488 1.4 17988 18753 2 1137.549054 569.7817 Serine\arginine-rich splicing factor 9 OS=Homo sapiens OX=9606 GN=SRSF9 PE=1 SV=1 4.37 3342.9 - 3.48E+06 - - - 0.1837 - 2.423 0.374 - 516.1 1 2 0 0.0002 10 0 0 0 1.08E+08 7.75E+07 - - - 4.2736 0.9998 221125_WJC_METTL3_EV_vs_WT_F02.18754.18754.2 0.53 16-Sep R.DNLAEDIMR.L "sp|P08670|VIME_HUMAN,tr|B0YJC4|B0YJC4_HUMAN" 2 1075.4968 1.89 17989 18754 2 1075.496838 538.7557 Vimentin OS=Homo sapiens OX=9606 GN=VIM PE=1 SV=4 4.03 3343 - 3.11E+06 - - - 0.027 - 2.05 0.389 - 428.2 1 2 0 0 9 0 0 0 1.86E+09 9.80E+08 - - - 3.9909 1 221125_WJC_METTL3_EV_vs_WT_F02.18756.18756.2 8.81E-06 22-Dec R.GVIDMGNSLIER.G "sp|Q13813|SPTN1_HUMAN,tr|A0A0D9SF54|A0A0D9SF54_HUMAN,tr|A0A0D9SGF6|A0A0D9SGF6_HUMAN" 3 1302.6602 1.43 17991 18756 2 1302.662408 652.3374 "Spectrin alpha chain, non-erythrocytic 1 OS=Homo sapiens OX=9606 GN=SPTAN1 PE=1 SV=3" 4.37 3343.1 - 2.77E+06 - - - 1.7057 - 2.748 0.55 - 640.1 1 2 0 0.0022 12 0 0 0 3.24E+07 2.27E+07 - - - 5.7624 0.9999 221125_WJC_METTL3_EV_vs_WT_F02.18757.18757.2 6.30E-06 20-Nov K.AEFTSPPSLFK[136.11].T "sp|Q6UN15|FIP1_HUMAN,tr|A0A0B4J203|A0A0B4J203_HUMAN" 2 1230.6376 1.08 17992 18757 2 1230.637065 616.3261 Pre-mRNA 3'-end-processing factor FIP1 OS=Homo sapiens OX=9606 GN=FIP1L1 PE=1 SV=1 6.05 3343.2 - 2.55E+06 - - - -0.4266 - 2.129 0.547 - 410.4 1 2 0 -0.0005 11 0 0 0 4.32E+07 4.01E+07 - - - 5.1252 0.9996 221125_WJC_METTL3_EV_vs_WT_F02.18758.18758.2 1.47E-05 26-Dec K.TLINAEDPPMVVVR[166.11].K "sp|P46940|IQGA1_HUMAN,tr|H0YLE8|H0YLE8_HUMAN,tr|A0A0J9YXZ5|A0A0J9YXZ5_HUMAN" 3 1562.8366 1.16 17993 18758 2 1562.837794 782.4256 Ras GTPase-activating-like protein IQGAP1 OS=Homo sapiens OX=9606 GN=IQGAP1 PE=1 SV=1 4.37 3343.3 - 1.93E+06 - - - 0.7742 - 1.811 0.391 - 248.6 1 2 0 0.0012 14 0 0 0 2.36E+07 2.03E+07 - - - 3.4189 0.9992 221125_WJC_METTL3_EV_vs_WT_F02.18760.18760.2 0.0033 20-Aug K.VPLFSPNFSEK[136.11].V "sp|Q9BQ52|RNZ2_HUMAN,tr|G5E9D5|G5E9D5_HUMAN,tr|E7ES68|E7ES68_HUMAN" 3 1271.6641 1.12 17995 18760 2 1271.662463 636.8393 Zinc phosphodiesterase ELAC protein 2 OS=Homo sapiens OX=9606 GN=ELAC2 PE=1 SV=2 5.97 3343.5 - 1.28E+06 - - - -1.318 - 1.658 0.33 - 185.2 1 2 0 -0.0017 11 0 0 0 1.45E+07 1.29E+07 - - - 2.8457 0.9988 221125_WJC_METTL3_EV_vs_WT_F02.18761.18761.2 0.00188 12-Aug R.DGFGFIK.C "sp|O75534|CSDE1_HUMAN,tr|E9PLT0|E9PLT0_HUMAN" 2 782.3963 0.64 17996 18761 2 782.396668 392.2054 Cold shock domain-containing protein E1 OS=Homo sapiens OX=9606 GN=CSDE1 PE=1 SV=2 5.84 3343.6 - 1.20E+06 - - - 0.4831 - 1.384 0.301 - 234.7 1 2 0 0.0004 7 0 0 0 7.53E+06 1.18E+07 - - - 2.2938 0.9969 221125_WJC_METTL3_EV_vs_WT_F02.18762.18762.2 0.0023 16-Sep K.SSLNPILFR[166.11].G "sp|P39656|OST48_HUMAN,tr|U3KQ84|U3KQ84_HUMAN,tr|A0A0C4DGS1|A0A0C4DGS1_HUMAN" 3 1055.6003 1.34 17997 18762 2 1055.602904 528.8074 Dolichyl-diphosphooligosaccharide--protein glycosyltransferase 48 kDa subunit OS=Homo sapiens OX=9606 GN=DDOST PE=1 SV=4 9.47 3343.7 - 1.18E+06 - - - 2.4668 - 1.505 0.293 - 217.1 1 2 0 0.0026 9 0 0 0 7.06E+07 5.26E+07 - - - 2.3869 0.9994 221125_WJC_METTL3_EV_vs_WT_F02.18763.18763.2 0.00611 16-Sep R.FAVGIVIGR.N "sp|Q96I24|FUBP3_HUMAN,sp|Q96AE4|FUBP1_HUMAN,tr|E9PEB5|E9PEB5_HUMAN" 3 930.5651 1.16 17998 18763 2 930.563637 466.2898 Far upstream element-binding protein 3 OS=Homo sapiens OX=9606 GN=FUBP3 PE=1 SV=2 9.75 3343.8 - 819891 - - - -1.5582 - 1.789 0.363 - 273.7 1 2 0 -0.0014 9 0 0 0 1.77E+07 1.52E+07 - - - 3.4044 0.9969 221125_WJC_METTL3_EV_vs_WT_F02.18764.18764.2 3.59E-05 20-Nov K.VPLFSPNFSEK.V "sp|Q9BQ52|RNZ2_HUMAN,tr|G5E9D5|G5E9D5_HUMAN,tr|E7ES68|E7ES68_HUMAN" 3 1263.6499 1.12 17999 18764 2 1263.656169 632.8322 Zinc phosphodiesterase ELAC protein 2 OS=Homo sapiens OX=9606 GN=ELAC2 PE=1 SV=2 5.97 3343.9 - 708781 - - - 4.9302 - 2.042 0.461 - 457.4 1 2 0 0.0062 11 0 0 0 1.45E+07 1.29E+07 - - - 4.3753 0.9873 221125_WJC_METTL3_EV_vs_WT_F02.18765.18765.2 0.000797 18-Dec R.K[136.11]PLVIIAEDV.D "sp|P10809|CH60_HUMAN,tr|A0A7I2V2X6|A0A7I2V2X6_HUMAN,tr|A0A7I2YQK6|A0A7I2YQK6_HUMAN,tr|A0A7I2V599|A0A7I2V599_HUMAN,tr|A0A7I2YQ71|A0A7I2YQ71_HUMAN,tr|A0A7I2V5M1|A0A7I2V5M1_HUMAN,tr|A0A7I2V5K3|A0A7I2V5K3_HUMAN,tr|A0A7I2V369|A0A7I2V369_HUMAN" 8 1103.6682 1.81 18000 18765 2 1103.668011 552.8414 "60 kDa heat shock protein, mitochondrial OS=Homo sapiens OX=9606 GN=HSPD1 PE=1 SV=2" 4.37 3344 - 704495 - - - -0.1368 - 2.039 0.4 - 328.7 1 1 0 -0.0002 10 0 0 0 9.63E+06 5.33E+06 - - - 3.984 0.9987 221125_WJC_METTL3_EV_vs_WT_F02.18766.18766.3 0.00671 Aug-32 K.FRLILIESR.L sp|P62277|RS13_HUMAN 1 1145.6921 0.73 18001 18766 3 1145.692252 382.9046 40S ribosomal protein S13 OS=Homo sapiens OX=9606 GN=RPS13 PE=1 SV=2 9.6 3344.1 - 612786 - - - 0.1519 - 1.846 0.35 - 112.1 1 2 1 0.0002 9 0 0 0 3.23E+06 4.44E+06 - - - 4.2896 0.9998 221125_WJC_METTL3_EV_vs_WT_F02.18771.18771.2 0.00178 16-Sep R.DNLAEDIMR[166.11].L "sp|P08670|VIME_HUMAN,tr|B0YJC4|B0YJC4_HUMAN" 2 1085.5051 1.89 18004 18771 2 1085.50585 543.7598 Vimentin OS=Homo sapiens OX=9606 GN=VIM PE=1 SV=4 4.03 3344.8 - 1.15E+07 - - - 0.7103 - 1.87 0.461 - 427.9 1 2 0 0.0008 9 0 0 0 1.86E+09 9.80E+08 - - - 4.2566 0.9994 221125_WJC_METTL3_EV_vs_WT_F02.18772.18772.2 0.275 16-Oct K.SSLNPILFR.G "sp|P39656|OST48_HUMAN,tr|U3KQ84|U3KQ84_HUMAN,tr|A0A0C4DGS1|A0A0C4DGS1_HUMAN" 3 1045.592 1.31 18005 18772 2 1045.592572 523.8033 Dolichyl-diphosphooligosaccharide--protein glycosyltransferase 48 kDa subunit OS=Homo sapiens OX=9606 GN=DDOST PE=1 SV=4 9.47 3344.9 - 3.38E+06 - - - 0.5184 - 2.019 0.263 - 296.3 1 2 0 0.0005 9 0 0 0 7.06E+07 5.38E+07 - - - 3.016 0.9997 221125_WJC_METTL3_EV_vs_WT_F02.18774.18774.3 0.000258 Sep-44 R.LNVGGTVFLTTR.Q "sp|Q8N5Z5|KCD17_HUMAN,tr|A0A087WX35|A0A087WX35_HUMAN" 2 1276.7139 3.42 18007 18774 3 1276.717126 426.5786 BTB\POZ domain-containing protein KCTD17 OS=Homo sapiens OX=9606 GN=KCTD17 PE=1 SV=3 9.75 3344.9 - 2.93E+06 - - - 2.4986 - 1.814 0.448 - 88.1 1 2 0 0.0032 12 0 0 0 1.98E+07 5.78E+06 - - - 5.1846 0.995 221125_WJC_METTL3_EV_vs_WT_F02.18775.18775.2 0.0933 14-Aug K.EFTLEFSR[166.11].D "sp|P16615|AT2A2_HUMAN,sp|Q93084|AT2A3_HUMAN,sp|O14983|AT2A1_HUMAN,tr|H7C5W9|H7C5W9_HUMAN" 4 1037.5057 1.85 18008 18775 2 1037.508217 519.7601 Sarcoplasmic\endoplasmic reticulum calcium ATPase 2 OS=Homo sapiens OX=9606 GN=ATP2A2 PE=1 SV=1 4.53 3345 - 2.65E+06 - - - 2.3961 - 1.492 0.228 - 323.4 1 2 0 0.0025 8 0 0 0 3.19E+07 1.72E+07 - - - 1.931 0.9997 221125_WJC_METTL3_EV_vs_WT_F02.18777.18777.2 0.00291 13/26 K.NLEPEWAAAASEVK.E sp|Q15084|PDIA6_HUMAN 1 1513.7413 1.57 18010 18777 2 1513.737404 757.8779 Protein disulfide-isomerase A6 OS=Homo sapiens OX=9606 GN=PDIA6 PE=1 SV=1 4.25 3345.1 - 2.13E+06 - - - -2.5559 - 2.601 0.547 - 603.4 1 2 0 -0.0039 14 0 0 0 7.57E+07 4.83E+07 - - - 5.4787 0.9998 221125_WJC_METTL3_EV_vs_WT_F02.18778.18778.2 0.00409 13/20 R.STLAALIAAQR.V "sp|Q9HCJ3|RAVR2_HUMAN,tr|E9PE10|E9PE10_HUMAN" 2 1113.6506 1.5 18011 18778 2 1113.651782 557.8326 Ribonucleoprotein PTB-binding 2 OS=Homo sapiens OX=9606 GN=RAVER2 PE=1 SV=2 9.47 3345.2 - 2.05E+06 - - - 1.0551 - 2.467 0.383 - 500.8 1 2 0 0.0012 11 0 0 0 1.30E+08 8.68E+07 - - - 4.3123 0.9999 221125_WJC_METTL3_EV_vs_WT_F02.18779.18779.3 0.776 16/36 R.YIHLENLLAR.S sp|Q2TAY7|SMU1_HUMAN 1 1240.6928 1.12 18012 18779 3 1240.692272 414.5715 WD40 repeat-containing protein SMU1 OS=Homo sapiens OX=9606 GN=SMU1 PE=1 SV=2 6.75 3345.3 - 1.93E+06 - - - -0.4312 - 2.854 0.291 - 293.6 1 2 0 -0.0005 10 0 0 0 8.00E+07 7.12E+07 - - - 4.8469 0.9998 221125_WJC_METTL3_EV_vs_WT_F02.18780.18780.2 3.04E-05 18-Nov K.GNFNYIEFTR[166.11].L "sp|O14950|ML12B_HUMAN,sp|P19105|ML12A_HUMAN,tr|J3QRS3|J3QRS3_HUMAN" 3 1269.6018 1.21 18013 18780 2 1269.604306 635.8082 Myosin regulatory light chain 12B OS=Homo sapiens OX=9606 GN=MYL12B PE=1 SV=2 6 3345.4 - 1.91E+06 - - - 2.0077 - 2.137 0.55 - 548.4 1 2 0 0.0025 10 0 0 0 4.27E+08 3.54E+08 - - - 5.2222 0.9998 221125_WJC_METTL3_EV_vs_WT_F02.18781.18781.2 0.000957 26-Nov K.SAWLSGYENPVVSR.L sp|P13674|P4HA1_HUMAN 1 1563.7682 0.42 18014 18781 2 1563.766554 782.8914 Prolyl 4-hydroxylase subunit alpha-1 OS=Homo sapiens OX=9606 GN=P4HA1 PE=1 SV=2 5.72 3345.4 - 1.84E+06 - - - -1.0251 - 2.081 0.498 - 192.4 1 2 0 -0.0016 14 0 0 0 1.37E+07 3.23E+07 - - - 4.5578 1 221125_WJC_METTL3_EV_vs_WT_F02.18782.18782.3 0.000548 13/36 R.YIHLENLLAR[166.11].S sp|Q2TAY7|SMU1_HUMAN 1 1250.7011 1.12 18015 18782 3 1250.70053 417.9076 WD40 repeat-containing protein SMU1 OS=Homo sapiens OX=9606 GN=SMU1 PE=1 SV=2 6.75 3345.5 - 1.83E+06 - - - -0.4374 - 2.692 0.435 - 365.6 1 2 0 -0.0005 10 0 0 0 8.00E+07 7.12E+07 - - - 6.2817 1 221125_WJC_METTL3_EV_vs_WT_F02.18783.18783.2 4.08E-08 18-Nov K.GNFNYIEFTR.L "sp|O14950|ML12B_HUMAN,sp|P19105|ML12A_HUMAN,tr|J3QRS3|J3QRS3_HUMAN" 3 1259.5935 1.21 18016 18783 2 1259.593078 630.804 Myosin regulatory light chain 12B OS=Homo sapiens OX=9606 GN=MYL12B PE=1 SV=2 6 3345.6 - 1.65E+06 - - - -0.3247 - 2.299 0.592 - 567.4 1 2 0 -0.0004 10 0 0 0 4.28E+08 3.54E+08 - - - 5.7371 0.9995 221125_WJC_METTL3_EV_vs_WT_F02.18784.18784.2 0.0047 14-Aug R.QDVYDLLK[136.11].T "sp|Q99460|PSMD1_HUMAN,tr|A0A7I2V4X0|A0A7I2V4X0_HUMAN,tr|A0A7I2V2K8|A0A7I2V2K8_HUMAN,tr|A0A7I2YQY1|A0A7I2YQY1_HUMAN,tr|A0A7I2V523|A0A7I2V523_HUMAN,tr|A0A7I2V641|A0A7I2V641_HUMAN,tr|A0A7I2V491|A0A7I2V491_HUMAN,tr|A0A7I2YQI9|A0A7I2YQI9_HUMAN,tr|A0A7I2V262|A0A7I2V262_HUMAN,tr|A0A087WW66|A0A087WW66_HUMAN,tr|A0A7P0MW50|A0A7P0MW50_HUMAN,tr|A0A7I2V5C8|A0A7I2V5C8_HUMAN,tr|A0A7I2V479|A0A7I2V479_HUMAN" 13 1000.5321 0.5 18017 18784 2 1000.531505 501.2733 26S proteasome non-ATPase regulatory subunit 1 OS=Homo sapiens OX=9606 GN=PSMD1 PE=1 SV=2 4.21 3345.6 - 1.63E+06 - - - -0.5567 - 1.65 0.336 - 229.5 1 2 0 -0.0006 8 0 0 0 2.72E+07 5.42E+07 - - - 3.0328 0.9771 221125_WJC_METTL3_EV_vs_WT_F02.18785.18785.2 0.73 18-Sep K.AAFITYLQAK.Q sp|Q96T58|MINT_HUMAN 1 1124.623 0.9 18018 18785 2 1124.621838 563.3188 Msx2-interacting protein OS=Homo sapiens OX=9606 GN=SPEN PE=1 SV=1 8.63 3345.7 - 1.38E+06 - - - -1.0297 - 1.279 0.063 - 181.8 1 2 0 -0.0012 10 0 0 0 1.88E+07 2.08E+07 - - - 0.1928 0.998 221125_WJC_METTL3_EV_vs_WT_F02.18786.18786.2 0.493 14-Aug K.MNFESFVK[136.11].D "sp|P43246|MSH2_HUMAN,tr|A0A2R8YG02|A0A2R8YG02_HUMAN,tr|A0A2R8Y7S8|A0A2R8Y7S8_HUMAN,tr|E9PHA6|E9PHA6_HUMAN,tr|A0A2R8YFH0|A0A2R8YFH0_HUMAN,tr|A0A2R8Y6P0|A0A2R8Y6P0_HUMAN" 6 1008.483 0.65 18019 18786 2 1008.483851 505.2488 DNA mismatch repair protein Msh2 OS=Homo sapiens OX=9606 GN=MSH2 PE=1 SV=1 5.75 3345.8 - 1.36E+06 - - - 0.8409 - 1.688 0.182 - 243.4 1 2 0 0.0008 8 0 0 0 1.07E+07 1.64E+07 - - - 1.964 1 221125_WJC_METTL3_EV_vs_WT_F02.18789.18789.2 3.35E-08 16/28 R.AALVDLEPGTMDSVR[166.11].S "sp|Q9BUF5|TBB6_HUMAN,tr|K7EJZ4|K7EJZ4_HUMAN,tr|K7EQT3|K7EQT3_HUMAN,tr|K7EN98|K7EN98_HUMAN,tr|K7ERA8|K7ERA8_HUMAN,tr|K7ESQ3|K7ESQ3_HUMAN,tr|K7EL29|K7EL29_HUMAN,tr|K7EPE5|K7EPE5_HUMAN,tr|K7EJ64|K7EJ64_HUMAN" 9 1582.79 1.9 18022 18789 2 1582.786732 792.4023 Tubulin beta-6 chain OS=Homo sapiens OX=9606 GN=TUBB6 PE=1 SV=1 4.03 3346.1 - 988860 - - - -2.0824 - 3.096 0.594 - 587.8 1 2 0 -0.0033 15 0 0 0 3.82E+07 2.01E+07 - - - 6.2057 1 221125_WJC_METTL3_EV_vs_WT_F02.18794.18794.2 3.89E-06 14/26 K.LGFTQGDVGLAMGK[136.11].L "sp|P14859|PO2F1_HUMAN,sp|P09086|PO2F2_HUMAN,sp|Q9UKI9|PO2F3_HUMAN,tr|U3KQ96|U3KQ96_HUMAN,tr|U3KQN1|U3KQN1_HUMAN,tr|H0YKT2|H0YKT2_HUMAN,tr|H0YNW1|H0YNW1_HUMAN,tr|B5ME60|B5ME60_HUMAN,tr|A0A0C4DG88|A0A0C4DG88_HUMAN,tr|H0YLL6|H0YLL6_HUMAN" 10 1400.7213 1.64 18025 18794 2 1400.720654 701.3679 "POU domain, class 2, transcription factor 1 OS=Homo sapiens OX=9606 GN=POU2F1 PE=1 SV=2" 5.84 3346.8 - 1.82E+07 - - - -0.4869 - 2.788 0.594 - 455 1 2 0 -0.0007 14 0 0 0 4.09E+08 2.49E+08 - - - 6.0011 0.9996 221125_WJC_METTL3_EV_vs_WT_F02.18797.18797.2 0.000642 20-Dec R.STLAALIAAQR[166.11].V "sp|Q9HCJ3|RAVR2_HUMAN,tr|E9PE10|E9PE10_HUMAN" 2 1123.6589 1.49 18028 18797 2 1123.66095 562.8367 Ribonucleoprotein PTB-binding 2 OS=Homo sapiens OX=9606 GN=RAVER2 PE=1 SV=2 9.47 3346.9 - 4.05E+06 - - - 1.8449 - 2.337 0.386 - 475.4 1 2 0 0.0021 11 0 0 0 1.30E+08 8.69E+07 - - - 4.1877 1 221125_WJC_METTL3_EV_vs_WT_F02.18798.18798.2 7.62E-09 16/28 R.AALVDLEPGTMDSVR.S "sp|Q9BUF5|TBB6_HUMAN,tr|K7EJZ4|K7EJZ4_HUMAN,tr|K7EQT3|K7EQT3_HUMAN,tr|K7EN98|K7EN98_HUMAN,tr|K7ERA8|K7ERA8_HUMAN,tr|K7ESQ3|K7ESQ3_HUMAN,tr|K7EL29|K7EL29_HUMAN,tr|K7EPE5|K7EPE5_HUMAN,tr|K7EJ64|K7EJ64_HUMAN" 9 1572.7818 1.9 18029 18798 2 1572.77966 787.3982 Tubulin beta-6 chain OS=Homo sapiens OX=9606 GN=TUBB6 PE=1 SV=1 4.03 3347 - 2.59E+06 - - - -1.3339 - 2.912 0.589 - 599.7 1 2 0 -0.0021 15 0 0 0 3.81E+07 2.01E+07 - - - 6.0185 0.9994 221125_WJC_METTL3_EV_vs_WT_F02.18799.18799.2 0.000381 18-Sep K.AAFITYLQAK[136.11].Q sp|Q96T58|MINT_HUMAN 1 1132.6372 0.92 18030 18799 2 1132.635358 567.3259 Msx2-interacting protein OS=Homo sapiens OX=9606 GN=SPEN PE=1 SV=1 8.63 3347.1 - 1.27E+06 - - - -1.6228 - 1.699 0.392 - 171.9 1 2 0 -0.0018 10 0 0 0 1.92E+07 2.08E+07 - - - 3.4152 0.9833 221125_WJC_METTL3_EV_vs_WT_F02.18800.18800.3 0.00919 Dec-44 R.HLPGAFFLGAER[166.11].G sp|Q9NUD5|ZCHC3_HUMAN 1 1323.6963 0.93 18031 18800 3 1323.697648 442.2394 Zinc finger CCHC domain-containing protein 3 OS=Homo sapiens OX=9606 GN=ZCCHC3 PE=1 SV=2 6.75 3347.2 - 1.03E+06 - - - 0.9987 - 2.128 0.083 - 111.8 1 2 0 0.0013 12 0 0 0 1.31E+07 1.41E+07 - - - 1.5583 0.9976 221125_WJC_METTL3_EV_vs_WT_F02.18801.18801.2 0.00522 14-Jul K.LFDFVNAK[136.11].K "sp|Q08945|SSRP1_HUMAN,tr|A0A0U1RRK2|A0A0U1RRK2_HUMAN" 2 960.516 0.57 18032 18801 2 960.514434 481.2653 FACT complex subunit SSRP1 OS=Homo sapiens OX=9606 GN=SSRP1 PE=1 SV=1 5.84 3347.3 - 1.01E+06 - - - -1.6491 - 1.341 0.29 - 109.1 1 2 0 -0.0016 8 0 0 0 2.13E+07 3.72E+07 - - - 2.0674 0.9995 221125_WJC_METTL3_EV_vs_WT_F02.18803.18803.2 0.000848 16-Sep R.FAVGIVIGR[166.11].N "sp|Q96I24|FUBP3_HUMAN,sp|Q96AE4|FUBP1_HUMAN,tr|E9PEB5|E9PEB5_HUMAN" 3 940.5734 1.84 18034 18803 2 940.572091 471.294 Far upstream element-binding protein 3 OS=Homo sapiens OX=9606 GN=FUBP3 PE=1 SV=2 9.75 3347.6 - 663187 - - - -1.346 - 1.887 0.35 - 298.2 1 2 0 -0.0013 9 0 0 0 1.73E+07 9.38E+06 - - - 3.4628 0.9925 221125_WJC_METTL3_EV_vs_WT_F02.18805.18805.3 0.00106 Nov-36 K.WVPLHLDVVR.S "sp|Q659C4|LAR1B_HUMAN,tr|H0Y9K3|H0Y9K3_HUMAN,tr|A0A3B3ISF8|A0A3B3ISF8_HUMAN,tr|A0A3B3ISF0|A0A3B3ISF0_HUMAN,tr|A0A3B3IT29|A0A3B3IT29_HUMAN,tr|D6R9W6|D6R9W6_HUMAN,tr|G3V0E9|G3V0E9_HUMAN" 7 1232.703 0.29 18036 18805 3 1232.702265 411.9083 La-related protein 1B OS=Homo sapiens OX=9606 GN=LARP1B PE=1 SV=2 6.74 3347.8 - 318121 - - - -0.5776 - 1.924 0.137 - 250.2 1 2 0 -0.0007 10 0 0 0 6.29E+06 2.21E+07 - - - 1.9784 0.9997 221125_WJC_METTL3_EV_vs_WT_F02.18809.18809.2 0.00976 18-Sep K.FAAQELIEVK[136.11].R "sp|Q86U44|MTA70_HUMAN,tr|F5H6D8|F5H6D8_HUMAN,tr|H0YFV6|H0YFV6_HUMAN,tr|B4DTN4|B4DTN4_HUMAN" 4 1154.6427 0.04 18038 18809 2 1154.642505 578.3286 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 4.53 3348.3 - 2.88E+07 - - - -0.1472 - 2.016 0.345 - 214.8 1 2 0 -0.0002 10 0 0 0 8.44E+06 2.27E+08 - - - 3.5461 0.9997 221125_WJC_METTL3_EV_vs_WT_F02.18812.18812.2 0.00402 16-Oct K.TVVEALFQR.D sp|P57740|NU107_HUMAN 1 1061.5869 1.36 18041 18812 2 1061.586743 531.8007 Nuclear pore complex protein Nup107 OS=Homo sapiens OX=9606 GN=NUP107 PE=1 SV=1 5.66 3348.5 - 2.85E+06 - - - -0.1903 - 1.839 0.377 - 388.1 1 2 0 -0.0002 9 0 0 0 4.32E+07 3.18E+07 - - - 3.588 0.987 221125_WJC_METTL3_EV_vs_WT_F02.18813.18813.2 0.337 16-Jul R.LDPFSSFSK.R sp|Q13948|CASP_HUMAN 1 1026.5022 2.2 18042 18813 2 1026.50294 514.2584 Protein CASP OS=Homo sapiens OX=9606 GN=CUX1 PE=1 SV=2 5.84 3348.5 - 2.66E+06 - - - 0.7092 - 1.185 0.137 - 142.9 1 2 0 0.0007 9 0 0 0 3.97E+07 1.81E+07 - - - 0.5437 0.9998 221125_WJC_METTL3_EV_vs_WT_F02.18814.18814.2 0.000142 18-Nov K.NADPILISLK[136.11].H "sp|Q9ULV4|COR1C_HUMAN,tr|H0YHL7|H0YHL7_HUMAN,tr|B4E3S0|B4E3S0_HUMAN" 3 1090.6478 0.96 18043 18814 2 1090.646859 546.3312 Coronin-1C OS=Homo sapiens OX=9606 GN=CORO1C PE=1 SV=1 5.84 3348.6 - 2.70E+06 - - - -0.8261 - 1.76 0.473 - 422.3 1 2 0 -0.0009 10 0 0 0 2.22E+07 2.32E+07 - - - 4.1123 0.9999 221125_WJC_METTL3_EV_vs_WT_F02.18816.18816.2 7.25E-05 24-Dec K.MLNGLEDSIGLSK[136.11].M "sp|P42704|LPPRC_HUMAN,tr|A0A804HI14|A0A804HI14_HUMAN,tr|A0A804HL40|A0A804HL40_HUMAN,tr|A0A804HKJ0|A0A804HKJ0_HUMAN,tr|A0A804HKR3|A0A804HKR3_HUMAN,tr|A0A804HIN4|A0A804HIN4_HUMAN,tr|A0A804HLG8|A0A804HLG8_HUMAN,tr|A0A804HJA1|A0A804HJA1_HUMAN,tr|A0A804HHY9|A0A804HHY9_HUMAN,tr|A0A804HI40|A0A804HI40_HUMAN,tr|A0A804HJZ1|A0A804HJZ1_HUMAN,tr|A0A804HIQ7|A0A804HIQ7_HUMAN,tr|A0A804HK30|A0A804HK30_HUMAN,tr|A0A804HKI2|A0A804HKI2_HUMAN,tr|A0A804HJI0|A0A804HJI0_HUMAN,tr|A0A804HKX6|A0A804HKX6_HUMAN,tr|A0A804HKK7|A0A804HKK7_HUMAN,tr|A0A804HIG4|A0A804HIG4_HUMAN" 18 1383.7159 0.47 18045 18816 2 1383.717414 692.8652 "Leucine-rich PPR motif-containing protein, mitochondrial OS=Homo sapiens OX=9606 GN=LRPPRC PE=1 SV=3" 4.37 3348.7 - 2.21E+06 - - - 1.0826 - 2.567 0.553 - 358.7 1 2 0 0.0015 13 0 0 0 2.12E+07 4.51E+07 - - - 5.5446 0.9996 221125_WJC_METTL3_EV_vs_WT_F02.18819.18819.2 0.00758 18-Nov R.YIHLENLLAR.S sp|Q2TAY7|SMU1_HUMAN 1 1240.6928 0.74 18048 18819 2 1240.692783 621.3537 WD40 repeat-containing protein SMU1 OS=Homo sapiens OX=9606 GN=SMU1 PE=1 SV=2 6.75 3349 - 1.13E+06 - - - -0.0193 - 1.78 0.343 - 474.7 1 2 0 0 10 0 0 0 1.46E+07 1.96E+07 - - - 3.1839 0.9999 221125_WJC_METTL3_EV_vs_WT_F02.18820.18820.2 6.13E-07 14/24 R.YLDDSWVNAPISK.S "sp|Q5VT06|CE350_HUMAN,tr|A2A4F6|A2A4F6_HUMAN,tr|E9PIK0|E9PIK0_HUMAN" 3 1506.7355 0.29 18049 18820 2 1506.735356 754.375 Centrosome-associated protein 350 OS=Homo sapiens OX=9606 GN=CEP350 PE=1 SV=1 4.21 3349.1 - 865276 - - - -0.0684 - 2.364 0.595 - 481.9 1 2 0 -0.0001 13 0 0 0 1.52E+07 5.20E+07 - - - 5.6438 0.9998 221125_WJC_METTL3_EV_vs_WT_F02.18825.18825.2 0.000193 18-Nov K.VDSLLENLEK[136.11].L "sp|P0DMR1|HNRC4_HUMAN,sp|P07910|HNRPC_HUMAN,sp|O60812|HNRC1_HUMAN,sp|B2RXH8|HNRC2_HUMAN,sp|B7ZW38|HNRC3_HUMAN,tr|B4DY08|B4DY08_HUMAN,tr|G3V5V7|G3V5V7_HUMAN,tr|B2R5W2|B2R5W2_HUMAN,tr|G3V4C1|G3V4C1_HUMAN,tr|A0A0G2JPF8|A0A0G2JPF8_HUMAN,tr|A0A0G2JNQ3|A0A0G2JNQ3_HUMAN,tr|G3V576|G3V576_HUMAN,tr|G3V2D6|G3V2D6_HUMAN,tr|G3V4W0|G3V4W0_HUMAN,tr|G3V2Q1|G3V2Q1_HUMAN" 15 1166.6274 1.55 18052 18825 2 1166.627179 584.321 Heterogeneous nuclear ribonucleoprotein C-like 4 OS=Homo sapiens OX=9606 GN=HNRNPCL4 PE=3 SV=1 4.14 3349.8 - 1.56E+07 - - - -0.2057 - 2.211 0.434 - 640.5 1 2 0 -0.0002 10 0 0 0 1.95E+09 1.25E+09 - - - 4.4612 0.9999 221125_WJC_METTL3_EV_vs_WT_F02.18826.18826.2 3.05E-06 18-Nov K.FFEQLDQIEK.Q "sp|O00268|TAF4_HUMAN,tr|A0A0G2JRY5|A0A0G2JRY5_HUMAN" 2 1295.6398 0.24 18053 18826 2 1295.639682 648.8272 Transcription initiation factor TFIID subunit 4 OS=Homo sapiens OX=9606 GN=TAF4 PE=1 SV=2 4.14 3349.8 - 6.73E+06 - - - -0.0664 - 2.05 0.562 - 283.9 1 2 0 -0.0001 10 0 0 0 1.34E+08 5.66E+08 - - - 5.1956 0.9925 221125_WJC_METTL3_EV_vs_WT_F02.18828.18828.3 0.28 Sep-44 R.SVYGGEFIQQLK.L sp|Q9NQG5|RPR1B_HUMAN 1 1367.7085 4.56 18055 18828 3 1367.706514 456.9101 Regulation of nuclear pre-mRNA domain-containing protein 1B OS=Homo sapiens OX=9606 GN=RPRD1B PE=1 SV=1 5.72 3350 - 1.12E+06 - - - -1.4638 - 1.706 0.202 - 84.1 2 2 0 -0.002 12 0 0 0 1.30E+07 2.84E+06 - - - 2.1328 0.9859 221125_WJC_METTL3_EV_vs_WT_F02.18831.18831.3 0.0231 Aug-40 R.ADLEMQIENLK.E "sp|Q04695|K1C17_HUMAN,tr|K7EPJ9|K7EPJ9_HUMAN,tr|F5GWP8|F5GWP8_HUMAN" 3 1302.649 2.35 18058 18831 3 1302.647051 435.2236 "Keratin, type I cytoskeletal 17 OS=Homo sapiens OX=9606 GN=KRT17 PE=1 SV=2" 4.14 3350.4 - 491369 - - - -1.4601 - 1.845 0.131 - 107.4 1 2 0 -0.0019 11 0 0 0 1.17E+07 4.97E+06 - - - 1.7399 0.9998 221125_WJC_METTL3_EV_vs_WT_F02.18834.18834.2 0.00114 13/20 R.QFLEVELDQAR[166.11].E "sp|Q14980|NUMA1_HUMAN,tr|A0A087WY61|A0A087WY61_HUMAN,tr|H0YFY6|H0YFY6_HUMAN,tr|K4DIE0|K4DIE0_HUMAN" 4 1356.6913 0.19 18060 18834 2 1356.691568 679.3529 Nuclear mitotic apparatus protein 1 OS=Homo sapiens OX=9606 GN=NUMA1 PE=1 SV=2 4.14 3350.7 - 2.35E+06 - - - 0.1975 - 2.072 0.445 - 401.1 1 2 0 0.0003 11 0 0 0 1.19E+07 6.16E+07 - - - 4.2985 0.9894 221125_WJC_METTL3_EV_vs_WT_F02.18845.18845.2 0.000239 18-Oct R.NHLLPDIVTC[160.03].V sp|Q9BSD7|NTPCR_HUMAN 1 1180.591 - 18069 18845 2 1180.589763 591.3028 Cancer-related nucleoside-triphosphatase OS=Homo sapiens OX=9606 GN=NTPCR PE=1 SV=1 5.08 3351.9 - 3.30E+06 - - - -1.085 - 1.743 0.539 - 443.1 1 1 0 -0.0013 10 0 0 0 - - - - - 4.5725 0.9999 221125_WJC_METTL3_EV_vs_WT_F02.18852.18852.2 1.63E-06 13/32 K.LLSNVAASQPANISVFK.R "sp|Q9BYP7|WNK3_HUMAN,tr|A0A087WYK2|A0A087WYK2_HUMAN" 2 1757.9676 4.48 18076 18852 2 1757.96631 879.9911 Serine\threonine-protein kinase WNK3 OS=Homo sapiens OX=9606 GN=WNK3 PE=1 SV=3 8.75 3352.7 - 633370 - - - -0.7253 - 2.668 0.561 - 444.3 1 2 0 -0.0013 17 0 0 0 6.69E+06 1.49E+06 - - - 5.5968 0.9998 221125_WJC_METTL3_EV_vs_WT_F02.18855.18855.2 8.86E-06 16-Nov K.YSTLSLFDK[136.11].Y "sp|Q5JSZ5|PRC2B_HUMAN,tr|A0A804HKL6|A0A804HKL6_HUMAN" 2 1080.5583 2.05 18077 18855 2 1080.55678 541.2864 Protein PRRC2B OS=Homo sapiens OX=9606 GN=PRRC2B PE=1 SV=2 5.83 3353.1 - 5.89E+06 - - - -1.3854 - 2.035 0.502 - 286.5 1 2 0 -0.0015 9 0 0 0 1.83E+08 8.90E+07 - - - 4.8038 1 221125_WJC_METTL3_EV_vs_WT_F02.18856.18856.3 1.08E-09 16/48 K.IILHNTMESLLER.G "sp|O15498|YKT6_HUMAN,tr|A0A7I2V4L6|A0A7I2V4L6_HUMAN" 2 1567.8392 2.01 18078 18856 3 1567.836123 523.6203 Synaptobrevin homolog YKT6 OS=Homo sapiens OX=9606 GN=YKT6 PE=1 SV=1 5.4 3353.1 - 4.34E+06 - - - -1.9709 - 3.094 0.609 - 515.2 1 2 0 -0.0031 13 0 0 0 8.42E+07 4.18E+07 - - - 8.3912 1 221125_WJC_METTL3_EV_vs_WT_F02.18861.18861.2 0.000758 17/28 K.VIIIGSGVSGLAAAR.Q "sp|O60341|KDM1A_HUMAN,tr|R4GMQ1|R4GMQ1_HUMAN" 2 1382.8245 1.43 18083 18861 2 1382.823079 692.4196 Lysine-specific histone demethylase 1A OS=Homo sapiens OX=9606 GN=KDM1A PE=1 SV=2 9.72 3353.6 - 3.02E+06 - - - -1.063 - 2.94 0.546 - 866.6 1 2 0 -0.0015 15 0 0 0 1.02E+08 7.11E+07 - - - 5.7246 0.8078 221125_WJC_METTL3_EV_vs_WT_F02.18862.18862.2 1.04 14-Jun R.REENSFDR[166.11].D sp|O43439|MTG8R_HUMAN 1 1061.4766 - 18084 18862 2 1061.472656 531.7456 Protein CBFA2T2 OS=Homo sapiens OX=9606 GN=CBFA2T2 PE=1 SV=1 4.68 3353.6 - 2.42E+06 - - - -3.6741 - 0.94 0.137 - 50 1 2 0 -0.0039 8 0 0 0 - - - - - -0.135 0.9897 221125_WJC_METTL3_EV_vs_WT_F02.18864.18864.2 0.631 14-Jul R.IVEVLLMK.D "sp|O75526|RMXL2_HUMAN,sp|P38159|RBMX_HUMAN,tr|H3BT71|H3BT71_HUMAN,tr|H0Y6E7|H0Y6E7_HUMAN,tr|H3BR27|H3BR27_HUMAN" 5 943.5776 1.57 18086 18864 2 943.575285 472.7961 "RNA-binding motif protein, X-linked-like-2 OS=Homo sapiens OX=9606 GN=RBMXL2 PE=1 SV=3" 6 3353.9 - 664808 - - - -2.4799 - 1.584 0.148 - 97.1 2 2 0 -0.0023 8 0 0 0 6.12E+06 3.90E+06 - - - 1.3861 0.9998 221125_WJC_METTL3_EV_vs_WT_F02.18871.18871.2 2.01E-05 14/28 K.VIIIGSGVSGLAAAR[166.11].Q "sp|O60341|KDM1A_HUMAN,tr|R4GMQ1|R4GMQ1_HUMAN" 2 1392.8328 1.43 18089 18871 2 1392.830688 697.4237 Lysine-specific histone demethylase 1A OS=Homo sapiens OX=9606 GN=KDM1A PE=1 SV=2 9.72 3354.8 - 3.25E+06 - - - -1.53 - 2.589 0.428 - 567.5 1 2 0 -0.0021 15 0 0 0 1.02E+08 7.11E+07 - - - 4.5403 0.9996 221125_WJC_METTL3_EV_vs_WT_F02.18873.18873.2 2.66E-05 18-Dec R.LGGIGQFLAK[136.11].A sp|Q08211|DHX9_HUMAN 1 1010.6004 0.83 18091 18873 2 1010.599357 506.3075 ATP-dependent RNA helicase A OS=Homo sapiens OX=9606 GN=DHX9 PE=1 SV=4 8.75 3355 - 3.45E+06 - - - -1.0479 - 2.212 0.301 - 333.9 1 2 0 -0.0011 10 0 0 0 6.32E+07 7.60E+07 - - - 3.4799 0.9995 221125_WJC_METTL3_EV_vs_WT_F02.18875.18875.2 0.000111 16-Sep R.DSWVFVGAK[136.11].G "sp|P98173|FAM3A_HUMAN,tr|Q5HY75|Q5HY75_HUMAN,tr|D3DWX8|D3DWX8_HUMAN" 3 1015.5218 1.02 18093 18875 2 1015.519635 508.7682 Protein FAM3A OS=Homo sapiens OX=9606 GN=FAM3A PE=1 SV=2 5.84 3355.2 - 2.38E+06 - - - -2.1634 - 1.611 0.479 - 280.3 1 2 0 -0.0022 9 0 0 0 4.83E+07 4.72E+07 - - - 3.9578 0.9999 221125_WJC_METTL3_EV_vs_WT_F02.18877.18877.3 3.46E-05 13/48 K.IILHNTMESLLER[166.11].G "sp|O15498|YKT6_HUMAN,tr|A0A7I2V4L6|A0A7I2V4L6_HUMAN" 2 1577.8475 2.07 18095 18877 3 1577.843322 526.9564 Synaptobrevin homolog YKT6 OS=Homo sapiens OX=9606 GN=YKT6 PE=1 SV=1 5.4 3355.4 - 2.07E+06 - - - -2.6371 - 2.881 0.485 - 319 1 2 0 -0.0042 13 0 0 0 8.42E+07 4.07E+07 - - - 6.815 0.9997 221125_WJC_METTL3_EV_vs_WT_F02.18880.18880.2 2.47E-07 14/24 R.MTHNLLLNYGLYR[166.11].K "sp|Q92769|HDAC2_HUMAN,sp|Q13547|HDAC1_HUMAN,tr|E5RHE7|E5RHE7_HUMAN,tr|E5RGV4|E5RGV4_HUMAN,tr|H3BM24|H3BM24_HUMAN,tr|E5RJ04|E5RJ04_HUMAN,tr|E5RG37|E5RG37_HUMAN,tr|E5RH52|E5RH52_HUMAN,tr|E5RK19|E5RK19_HUMAN,tr|E5RFP9|E5RFP9_HUMAN,tr|E5RFI6|E5RFI6_HUMAN,tr|Q5TEE2|Q5TEE2_HUMAN" 12 1616.8373 1.3 18098 18880 2 1616.833408 809.4259 Histone deacetylase 2 OS=Homo sapiens OX=9606 GN=HDAC2 PE=1 SV=2 8.36 3355.8 - 1.01E+06 - - - -2.3781 - 2.408 0.514 - 338.7 1 2 0 -0.0038 13 0 0 0 2.71E+07 2.08E+07 - - - 5.0917 0.9996 221125_WJC_METTL3_EV_vs_WT_F02.18883.18883.2 0.00121 18-Oct K.NYISAWELQR.K "sp|Q9BV38|WDR18_HUMAN,tr|U3KQC1|U3KQC1_HUMAN,tr|A0A087X237|A0A087X237_HUMAN,tr|A0A0A0MQU0|A0A0A0MQU0_HUMAN,tr|K7EKX5|K7EKX5_HUMAN,tr|K7EML4|K7EML4_HUMAN,tr|K7EIR0|K7EIR0_HUMAN" 7 1278.6357 1.25 18099 18883 2 1278.632937 640.3251 WD repeat-containing protein 18 OS=Homo sapiens OX=9606 GN=WDR18 PE=1 SV=2 6 3356.2 - 3.37E+06 - - - -2.1499 - 2.032 0.454 - 414.8 1 2 0 -0.0027 10 0 0 0 1.95E+08 1.56E+08 - - - 4.3725 0.9994 221125_WJC_METTL3_EV_vs_WT_F02.18884.18884.2 0.000157 13/18 R.LGGIGQFLAK.A sp|Q08211|DHX9_HUMAN 1 1002.5862 0.83 18100 18884 2 1002.585038 502.3004 ATP-dependent RNA helicase A OS=Homo sapiens OX=9606 GN=DHX9 PE=1 SV=4 8.75 3356.3 - 2.51E+06 - - - -1.175 - 2.366 0.232 - 381.8 1 2 0 -0.0012 10 0 0 0 6.32E+07 7.60E+07 - - - 3.1581 0.9995 221125_WJC_METTL3_EV_vs_WT_F02.18886.18886.2 1.07E-05 13/24 R.VGGNIEVLGFNAR.Q "sp|Q14839|CHD4_HUMAN,sp|Q8TDI0|CHD5_HUMAN,tr|A0A2R8Y4X2|A0A2R8Y4X2_HUMAN,tr|A0A2U3TZM0|A0A2U3TZM0_HUMAN,tr|A0A2R8Y5M9|A0A2R8Y5M9_HUMAN,tr|A0A2R8Y445|A0A2R8Y445_HUMAN,tr|A0A2R8YD40|A0A2R8YD40_HUMAN,tr|A0A2R8Y5J0|A0A2R8Y5J0_HUMAN,tr|A0A2R8Y425|A0A2R8Y425_HUMAN,tr|A0A2R8YFK9|A0A2R8YFK9_HUMAN,tr|A0A2R8Y8C1|A0A2R8Y8C1_HUMAN,tr|A0A0C4DGG9|A0A0C4DGG9_HUMAN,tr|A0A2R8YFD8|A0A2R8YFD8_HUMAN,tr|A0A2R8YDW2|A0A2R8YDW2_HUMAN,tr|A0A2R8Y7I0|A0A2R8Y7I0_HUMAN,tr|F5GWX5|F5GWX5_HUMAN,tr|K7EMY3|K7EMY3_HUMAN,tr|A0A2R8YER1|A0A2R8YER1_HUMAN,tr|A0A2R8Y7M9|A0A2R8Y7M9_HUMAN,tr|A0A2R8Y521|A0A2R8Y521_HUMAN,tr|A0A2R8YDJ9|A0A2R8YDJ9_HUMAN,tr|A0A2R8Y212|A0A2R8Y212_HUMAN,tr|A0A2R8YE38|A0A2R8YE38_HUMAN" 23 1344.715 1.12 18102 18886 2 1344.718903 673.3648 Chromodomain-helicase-DNA-binding protein 4 OS=Homo sapiens OX=9606 GN=CHD4 PE=1 SV=2 5.97 3356.5 - 968173 - - - 2.9032 - 2.443 0.469 - 532 1 2 0 0.0039 13 0 0 0 7.77E+07 6.92E+07 - - - 4.7963 0.9999 221125_WJC_METTL3_EV_vs_WT_F02.18892.18892.2 7.78E-08 15/24 K.VMQVLNADAIVVK.L sp|Q7KZF4|SND1_HUMAN 1 1398.7905 0.9 18106 18892 2 1398.789394 700.4025 Staphylococcal nuclease domain-containing protein 1 OS=Homo sapiens OX=9606 GN=SND1 PE=1 SV=1 5.81 3357.2 - 1.45E+06 - - - -0.7707 - 2.521 0.56 - 916.1 1 2 0 -0.0011 13 0 0 0 2.66E+07 2.94E+07 - - - 5.55 1 221125_WJC_METTL3_EV_vs_WT_F02.18895.18895.3 1.77E-08 16/48 R.MTHNLLLNYGLYR.K "sp|Q92769|HDAC2_HUMAN,sp|Q13547|HDAC1_HUMAN,tr|E5RHE7|E5RHE7_HUMAN,tr|E5RGV4|E5RGV4_HUMAN,tr|H3BM24|H3BM24_HUMAN,tr|E5RJ04|E5RJ04_HUMAN,tr|E5RG37|E5RG37_HUMAN,tr|E5RH52|E5RH52_HUMAN,tr|E5RK19|E5RK19_HUMAN,tr|E5RFP9|E5RFP9_HUMAN,tr|E5RFI6|E5RFI6_HUMAN,tr|Q5TEE2|Q5TEE2_HUMAN" 12 1606.829 1.42 18107 18895 3 1606.826465 536.6169 Histone deacetylase 2 OS=Homo sapiens OX=9606 GN=HDAC2 PE=1 SV=2 8.36 3357.6 - 1.04E+07 - - - -1.5671 - 2.963 0.565 - 389.6 1 2 0 -0.0025 13 0 0 0 2.12E+08 1.50E+08 - - - 7.7835 1 221125_WJC_METTL3_EV_vs_WT_F02.18896.18896.3 4.52E-05 13/48 R.MTHNLLLNYGLYR[166.11].K "sp|Q92769|HDAC2_HUMAN,sp|Q13547|HDAC1_HUMAN,tr|E5RHE7|E5RHE7_HUMAN,tr|E5RGV4|E5RGV4_HUMAN,tr|H3BM24|H3BM24_HUMAN,tr|E5RJ04|E5RJ04_HUMAN,tr|E5RG37|E5RG37_HUMAN,tr|E5RH52|E5RH52_HUMAN,tr|E5RK19|E5RK19_HUMAN,tr|E5RFP9|E5RFP9_HUMAN,tr|E5RFI6|E5RFI6_HUMAN,tr|Q5TEE2|Q5TEE2_HUMAN" 12 1616.8373 1.42 18108 18896 3 1616.835479 539.953 Histone deacetylase 2 OS=Homo sapiens OX=9606 GN=HDAC2 PE=1 SV=2 8.36 3357.6 - 6.77E+06 - - - -1.0972 - 2.526 0.478 - 284.1 1 2 0 -0.0018 13 0 0 0 2.12E+08 1.50E+08 - - - 6.3811 1 221125_WJC_METTL3_EV_vs_WT_F02.18902.18902.2 7.17E-08 14/22 R.NNLAGAEELFAR[166.11].K "sp|Q00610|CLH1_HUMAN,tr|A0A087WVQ6|A0A087WVQ6_HUMAN" 2 1313.6603 2.42 18112 18902 2 1313.656666 657.8374 Clathrin heavy chain 1 OS=Homo sapiens OX=9606 GN=CLTC PE=1 SV=5 4.53 3358.3 - 4.88E+06 - - - -2.7922 - 2.645 0.591 - 600.9 1 2 0 -0.0037 12 0 0 0 5.59E+08 2.30E+08 - - - 5.9642 1 221125_WJC_METTL3_EV_vs_WT_F02.18908.18908.2 4.19E-07 18/24 R.VGGNIEVLGFNAR[166.11].Q "sp|Q14839|CHD4_HUMAN,sp|Q8TDI0|CHD5_HUMAN,tr|A0A2R8Y4X2|A0A2R8Y4X2_HUMAN,tr|A0A2U3TZM0|A0A2U3TZM0_HUMAN,tr|A0A2R8Y5M9|A0A2R8Y5M9_HUMAN,tr|A0A2R8Y445|A0A2R8Y445_HUMAN,tr|A0A2R8YD40|A0A2R8YD40_HUMAN,tr|A0A2R8Y5J0|A0A2R8Y5J0_HUMAN,tr|A0A2R8Y425|A0A2R8Y425_HUMAN,tr|A0A2R8YFK9|A0A2R8YFK9_HUMAN,tr|A0A2R8Y8C1|A0A2R8Y8C1_HUMAN,tr|A0A0C4DGG9|A0A0C4DGG9_HUMAN,tr|A0A2R8YFD8|A0A2R8YFD8_HUMAN,tr|A0A2R8YDW2|A0A2R8YDW2_HUMAN,tr|A0A2R8Y7I0|A0A2R8Y7I0_HUMAN,tr|F5GWX5|F5GWX5_HUMAN,tr|K7EMY3|K7EMY3_HUMAN,tr|A0A2R8YER1|A0A2R8YER1_HUMAN,tr|A0A2R8Y7M9|A0A2R8Y7M9_HUMAN,tr|A0A2R8Y521|A0A2R8Y521_HUMAN,tr|A0A2R8YDJ9|A0A2R8YDJ9_HUMAN,tr|A0A2R8Y212|A0A2R8Y212_HUMAN,tr|A0A2R8YE38|A0A2R8YE38_HUMAN" 23 1354.7233 1.12 18116 18908 2 1354.72182 678.3689 Chromodomain-helicase-DNA-binding protein 4 OS=Homo sapiens OX=9606 GN=CHD4 PE=1 SV=2 5.97 3359.1 - 4.36E+06 - - - -1.0696 - 3.093 0.536 - 1430.6 1 2 0 -0.0014 13 0 0 0 7.77E+07 6.92E+07 - - - 5.8974 0.9983 221125_WJC_METTL3_EV_vs_WT_F02.18909.18909.2 0.000217 18-Oct K.AINFNFGYAK.A "sp|P47897|SYQ_HUMAN,tr|B4DDN1|B4DDN1_HUMAN,tr|C9J165|C9J165_HUMAN,tr|A0A1B0GVU9|A0A1B0GVU9_HUMAN,tr|A0A0U1RR66|A0A0U1RR66_HUMAN" 5 1143.5713 1.67 18117 18909 2 1143.566537 572.7929 Glutamine--tRNA ligase OS=Homo sapiens OX=9606 GN=QARS1 PE=1 SV=1 8.63 3359.2 - 2.37E+06 - - - -4.1607 - 2.031 0.456 - 223.2 1 2 0 -0.0048 10 0 0 0 3.99E+07 2.40E+07 - - - 4.3852 0.9989 221125_WJC_METTL3_EV_vs_WT_F02.18912.18912.2 1.10E-05 26-Oct K.TLIDDDNPPVSFVK.F sp|P61964|WDR5_HUMAN 1 1558.7879 2.8 18120 18912 2 1558.781729 780.4012 WD repeat-containing protein 5 OS=Homo sapiens OX=9606 GN=WDR5 PE=1 SV=1 3.93 3359.6 - 1.07E+06 - - - -3.9518 - 2.12 0.54 - 212.2 1 2 0 -0.0062 14 0 0 0 2.07E+07 7.40E+06 - - - 4.9131 0.9992 221125_WJC_METTL3_EV_vs_WT_F02.18915.18915.2 6.28E-05 16-Sep R.DVTTFFSGK.A "sp|Q8N6T3|ARFG1_HUMAN,tr|F8VWH9|F8VWH9_HUMAN,tr|F8W1U7|F8W1U7_HUMAN,tr|E5RHH7|E5RHH7_HUMAN" 4 1000.4866 0.86 18121 18915 2 1000.483856 501.2506 ADP-ribosylation factor GTPase-activating protein 1 OS=Homo sapiens OX=9606 GN=ARFGAP1 PE=1 SV=2 5.84 3359.9 - 4.10E+06 - - - -2.7047 - 1.592 0.486 - 230.1 1 2 0 -0.0027 9 0 0 0 6.16E+07 7.12E+07 - - - 3.975 0.9987 221125_WJC_METTL3_EV_vs_WT_F02.18917.18917.2 0.00367 14-Jul R.DLIDFDDR.Q sp|P15924|DESP_HUMAN 1 1007.456 7.87 18123 18917 2 1007.453898 504.7353 Desmoplakin OS=Homo sapiens OX=9606 GN=DSP PE=1 SV=3 3.77 3360.1 - 3.45E+06 - - - -2.0765 - 1.582 0.33 - 224.6 1 2 0 -0.0021 8 0 0 0 7.82E+07 9.93E+06 - - - 2.8611 0.9991 221125_WJC_METTL3_EV_vs_WT_F02.18918.18918.2 0.000577 14-Sep K.WNLDELPK.F "sp|P17844|DDX5_HUMAN,tr|J3QR02|J3QR02_HUMAN,tr|X6RLV5|X6RLV5_HUMAN,tr|A0A7I2V507|A0A7I2V507_HUMAN,tr|J3KTA4|J3KTA4_HUMAN,tr|J3KTQ4|J3KTQ4_HUMAN,tr|A0A7I2V2S0|A0A7I2V2S0_HUMAN,tr|J3QRQ7|J3QRQ7_HUMAN" 8 1013.5182 1.85 18124 18918 2 1013.515904 507.7664 Probable ATP-dependent RNA helicase DDX5 OS=Homo sapiens OX=9606 GN=DDX5 PE=1 SV=1 4.37 3360.1 - 2.54E+06 - - - -2.2614 - 1.669 0.381 - 291 1 2 0 -0.0023 8 0 0 0 4.40E+08 2.38E+08 - - - 3.3992 0.9976 221125_WJC_METTL3_EV_vs_WT_F02.18919.18919.3 4.20E-06 19/52 K.FAASGGFLHHMAGL.S "sp|Q9BY77|PDIP3_HUMAN,tr|F6VRR5|F6VRR5_HUMAN,tr|F8WCX5|F8WCX5_HUMAN,tr|Q8WUT1|Q8WUT1_HUMAN" 4 1414.6816 - 18125 18919 3 1414.679625 472.5678 Polymerase delta-interacting protein 3 OS=Homo sapiens OX=9606 GN=POLDIP3 PE=1 SV=2 6.92 3360.3 - 1.80E+06 - - - -1.389 - 3.025 0.508 - 185 1 1 0 -0.002 14 0 0 0 - - - - - 7.1448 0.9924 221125_WJC_METTL3_EV_vs_WT_F02.18920.18920.3 0.000708 14/44 Q.ISALEEQLQQIR.A "sp|P13645|K1C10_HUMAN,tr|A0A1B0GVI3|A0A1B0GVI3_HUMAN" 2 1426.778 56.54 18126 18920 3 1426.777038 476.5999 "Keratin, type I cytoskeletal 10 OS=Homo sapiens OX=9606 GN=KRT10 PE=1 SV=6" 4.53 3360.4 - 1.61E+06 - - - -0.6693 - 2.792 0.369 - 289.5 1 1 0 -0.001 12 0 0 0 2.72E+07 4.81E+05 - - - 5.4997 0.9985 221125_WJC_METTL3_EV_vs_WT_F02.18924.18924.2 0.725 14-Aug K.WNLDELPK[136.11].F "sp|P17844|DDX5_HUMAN,tr|J3QR02|J3QR02_HUMAN,tr|X6RLV5|X6RLV5_HUMAN,tr|A0A7I2V507|A0A7I2V507_HUMAN,tr|J3KTA4|J3KTA4_HUMAN,tr|J3KTQ4|J3KTQ4_HUMAN,tr|A0A7I2V2S0|A0A7I2V2S0_HUMAN,tr|J3QRQ7|J3QRQ7_HUMAN" 8 1021.5324 1.79 18128 18924 2 1021.530359 511.7735 Probable ATP-dependent RNA helicase DDX5 OS=Homo sapiens OX=9606 GN=DDX5 PE=1 SV=1 4.37 3360.9 - 3.12E+06 - - - -1.9941 - 1.556 0.314 - 239.7 1 2 0 -0.002 8 0 0 0 2.44E+08 1.37E+08 - - - 2.693 1 221125_WJC_METTL3_EV_vs_WT_F02.18926.18926.3 2.20E-05 15/40 K.VFLHLADIYAK[136.11].S "sp|Q14690|RRP5_HUMAN,tr|A0A3B3IUD7|A0A3B3IUD7_HUMAN" 2 1296.7322 0.81 18130 18926 3 1296.73044 433.2513 Protein RRP5 homolog OS=Homo sapiens OX=9606 GN=PDCD11 PE=1 SV=3 6.71 3361.2 - 1.74E+06 - - - -1.3256 - 2.438 0.506 - 300.5 1 2 0 -0.0017 11 0 0 0 1.16E+07 1.44E+07 - - - 6.7126 0.9997 221125_WJC_METTL3_EV_vs_WT_F02.18929.18929.2 1.13 15/28 R.LLDAQLATGGIVDPR.L "sp|Q15149|PLEC_HUMAN,tr|H0YDN1|H0YDN1_HUMAN" 2 1537.8464 2.15 18133 18929 2 1537.843963 769.9305 Plectin OS=Homo sapiens OX=9606 GN=PLEC PE=1 SV=3 4.21 3361.5 - 2.33E+06 - - - -1.5892 - 2.708 0.381 - 397.3 1 2 0 -0.0024 15 0 0 0 2.63E+07 1.22E+07 - - - 4.3035 1 221125_WJC_METTL3_EV_vs_WT_F02.18930.18930.2 1.04E-09 18/32 K.MGGMEGPFGGGMENMGR.F "sp|P52272|HNRPM_HUMAN,tr|M0QYL3|M0QYL3_HUMAN,tr|A0A087X0X3|A0A087X0X3_HUMAN,tr|M0QZM1|M0QZM1_HUMAN" 4 1713.6732 1.46 18134 18930 2 1713.672521 857.8439 Heterogeneous nuclear ribonucleoprotein M OS=Homo sapiens OX=9606 GN=HNRNPM PE=1 SV=3 4.53 3361.7 - 1.24E+06 - - - -0.3682 - 3.467 0.79 - 1071.8 1 2 0 -0.0006 17 0 0 0 2.22E+07 1.52E+07 - - - 7.9324 1 221125_WJC_METTL3_EV_vs_WT_F02.18932.18932.3 9.66E-06 15/40 K.VFLHLADIYAK.S "sp|Q14690|RRP5_HUMAN,tr|A0A3B3IUD7|A0A3B3IUD7_HUMAN" 2 1288.718 0.81 18136 18932 3 1288.716263 430.5799 Protein RRP5 homolog OS=Homo sapiens OX=9606 GN=PDCD11 PE=1 SV=3 6.71 3361.9 - 951717 - - - -1.316 - 2.663 0.468 - 341.4 1 2 0 -0.0017 11 0 0 0 1.16E+07 1.44E+07 - - - 6.5397 0.9971 221125_WJC_METTL3_EV_vs_WT_F02.18935.18935.2 0.119 16-Jul K.NLLNSVIGR[166.11].A "sp|Q7L2E3|DHX30_HUMAN,tr|H7BXY3|H7BXY3_HUMAN" 2 994.5799 0.9 18137 18935 2 994.579709 498.2972 ATP-dependent RNA helicase DHX30 OS=Homo sapiens OX=9606 GN=DHX30 PE=1 SV=1 9.75 3362.2 - 3.49E+06 - - - -0.191 - 1.474 0.181 - 163.9 1 2 0 -0.0002 9 0 0 0 4.94E+07 5.51E+07 - - - 1.5003 0.9997 221125_WJC_METTL3_EV_vs_WT_F02.18938.18938.2 0.00164 24-Dec R.LPPGFNDVDALC[160.03]R[166.11].A "sp|Q8IY67|RAVR1_HUMAN,tr|E9PAU2|E9PAU2_HUMAN,tr|A0A087WZ13|A0A087WZ13_HUMAN" 3 1482.7165 0.63 18140 18938 2 1482.718106 742.3655 Ribonucleoprotein PTB-binding 1 OS=Homo sapiens OX=9606 GN=RAVER1 PE=1 SV=1 4.21 3362.6 - 1.16E+06 - - - 1.1041 - 2.004 0.42 - 349.3 1 2 0 0.0016 13 0 0 0 3.55E+07 5.61E+07 - - - 3.9267 0.9987 221125_WJC_METTL3_EV_vs_WT_F02.18939.18939.2 2.95E-06 20-Dec R.AAELFVETIAK.D sp|Q9NR33|DPOE4_HUMAN 1 1190.6547 0.91 18141 18939 2 1190.658206 596.3346 DNA polymerase epsilon subunit 4 OS=Homo sapiens OX=9606 GN=POLE4 PE=1 SV=2 4.53 3362.7 - 1.09E+06 - - - 2.953 - 2.217 0.329 - 555.1 1 2 0 0.0035 11 0 0 0 1.17E+08 1.29E+08 - - - 3.6237 0.9999 221125_WJC_METTL3_EV_vs_WT_F02.18940.18940.2 0.000557 13/28 R.LLDAQLATGGIVDPR[166.11].L "sp|Q15149|PLEC_HUMAN,tr|H0YDN1|H0YDN1_HUMAN" 2 1547.8547 2.15 18142 18940 2 1547.85379 774.9346 Plectin OS=Homo sapiens OX=9606 GN=PLEC PE=1 SV=3 4.21 3362.9 - 891805 - - - -0.5731 - 2.797 0.45 - 275.5 1 2 0 -0.0009 15 0 0 0 2.63E+07 1.22E+07 - - - 4.8932 0.7881 221125_WJC_METTL3_EV_vs_WT_F02.18944.18944.2 0.0527 22-Jul R.IINEPTAAAIAY.G "sp|P11021|BIP_HUMAN,sp|P54652|HSP72_HUMAN,sp|P0DMV8|HS71A_HUMAN,sp|P34931|HS71L_HUMAN,sp|P11142|HSP7C_HUMAN,sp|P0DMV9|HS71B_HUMAN,sp|P17066|HSP76_HUMAN,tr|E9PKE3|E9PKE3_HUMAN,tr|E9PN89|E9PN89_HUMAN,tr|A0A7P0TB36|A0A7P0TB36_HUMAN,tr|E9PLF4|E9PLF4_HUMAN,tr|A0A7P0TAI0|A0A7P0TAI0_HUMAN,tr|Q53FA3|Q53FA3_HUMAN,tr|E9PI65|E9PI65_HUMAN,tr|E9PK54|E9PK54_HUMAN,tr|A0A0G2JIW1|A0A0G2JIW1_HUMAN" 16 1245.6605 - 18146 18944 2 1245.658282 623.8375 Endoplasmic reticulum chaperone BiP OS=Homo sapiens OX=9606 GN=HSPA5 PE=1 SV=2 4 3363.4 - 641976 - - - -1.7838 - 1.537 0.2 - 94 1 1 0 -0.0022 12 0 0 0 - - - - - 1.6485 0.9975 221125_WJC_METTL3_EV_vs_WT_F02.18945.18945.2 0.00169 20-Nov R.QAEMLDDLMEK.R "sp|P54819|KAD2_HUMAN,tr|A0A5F9ZHP2|A0A5F9ZHP2_HUMAN,tr|F8VY04|F8VY04_HUMAN,tr|F8W1A4|F8W1A4_HUMAN,tr|A0A5K1VW67|A0A5K1VW67_HUMAN,tr|F8VZG5|F8VZG5_HUMAN" 6 1321.5894 1.3 18147 18945 2 1321.58511 661.802 "Adenylate kinase 2, mitochondrial OS=Homo sapiens OX=9606 GN=AK2 PE=1 SV=2" 3.92 3363.5 - 571394 - - - -3.2378 - 1.48 0.402 - 211.8 1 2 0 -0.0043 11 0 0 0 4.76E+06 3.66E+06 - - - 3.0694 0.9997 221125_WJC_METTL3_EV_vs_WT_F02.18949.18949.2 0.0165 18-Oct K.NYISAWELQR[166.11].K "sp|Q9BV38|WDR18_HUMAN,tr|U3KQC1|U3KQC1_HUMAN,tr|A0A087X237|A0A087X237_HUMAN,tr|A0A0A0MQU0|A0A0A0MQU0_HUMAN,tr|K7EKX5|K7EKX5_HUMAN,tr|K7EML4|K7EML4_HUMAN,tr|K7EIR0|K7EIR0_HUMAN" 7 1288.644 1.25 18150 18949 2 1288.643604 645.3293 WD repeat-containing protein 18 OS=Homo sapiens OX=9606 GN=WDR18 PE=1 SV=2 6 3363.9 - 894571 - - - -0.2732 - 1.889 0.363 - 444.8 1 2 0 -0.0004 10 0 0 0 1.95E+08 1.57E+08 - - - 3.4974 0.9997 221125_WJC_METTL3_EV_vs_WT_F02.18950.18950.2 0.000658 20-Sep K.IEIDPQFQVVR.T sp|Q8N1N4|K2C78_HUMAN 1 1342.7245 5.13 18151 18950 2 1342.726948 672.3695 "Keratin, type II cytoskeletal 78 OS=Homo sapiens OX=9606 GN=KRT78 PE=1 SV=2" 4.37 3364 - 7.09E+06 - - - 1.8224 - 2.246 0.464 - 249.3 1 2 0 0.0024 11 0 0 0 7.15E+07 1.39E+07 - - - 4.6563 0.9985 221125_WJC_METTL3_EV_vs_WT_F02.18951.18951.2 0.0796 16-Aug R.QFLTQLMQK[136.11].E sp|Q15459|SF3A1_HUMAN 1 1143.6202 0.45 18152 18951 2 1143.621761 572.8174 Splicing factor 3A subunit 1 OS=Homo sapiens OX=9606 GN=SF3A1 PE=1 SV=1 8.75 3364 - 2.91E+06 - - - 1.3956 - 1.515 0.295 - 160.2 1 2 0 0.0016 9 0 0 0 1.99E+07 4.40E+07 - - - 2.4212 1 221125_WJC_METTL3_EV_vs_WT_F02.18953.18953.3 3.19E-05 14/44 K.NLLHQDAVDLFR.N "sp|P57105|SYJ2B_HUMAN,tr|A0A087X1F5|A0A087X1F5_HUMAN,tr|A0A087WYV9|A0A087WYV9_HUMAN" 3 1439.7521 1.23 18154 18953 3 1439.752723 480.9246 Synaptojanin-2-binding protein OS=Homo sapiens OX=9606 GN=SYNJ2BP PE=1 SV=2 5.21 3364.2 - 2.02E+06 - - - 0.4237 - 2.432 0.538 - 347.1 1 2 0 0.0006 12 0 0 0 1.44E+07 1.17E+07 - - - 7.0014 1 221125_WJC_METTL3_EV_vs_WT_F02.18956.18956.2 8.26E-07 14/22 R.MSVDAVEIETLR.K "sp|P78347|GTF2I_HUMAN,tr|A0A494C1K3|A0A494C1K3_HUMAN" 2 1361.6861 1.54 18157 18956 2 1361.684947 681.8503 General transcription factor II-I OS=Homo sapiens OX=9606 GN=GTF2I PE=1 SV=2 4.14 3364.5 - 1.28E+06 - - - -0.8218 - 3.029 0.578 - 950.1 1 2 0 -0.0011 12 0 0 0 3.47E+08 2.25E+08 - - - 6.2257 0.9994 221125_WJC_METTL3_EV_vs_WT_F02.18957.18957.2 0.00173 13/24 R.QLLTLSSELSQAR[166.11].D "sp|P15311|EZRI_HUMAN,tr|E7EQR4|E7EQR4_HUMAN" 2 1454.7968 1.9 18158 18957 2 1454.799541 728.4057 Ezrin OS=Homo sapiens OX=9606 GN=EZR PE=1 SV=4 6 3364.6 - 1.07E+06 - - - 1.8649 - 2.404 0.318 - 686.6 1 2 0 0.0027 13 0 0 0 1.57E+07 8.27E+06 - - - 3.6401 0.9998 221125_WJC_METTL3_EV_vs_WT_F02.18958.18958.3 0.00265 Dec-36 M.PR[166.11]YELALILK[136.11].A sp|P82932|RT06_HUMAN 1 1232.7612 5 18159 18958 3 1232.761749 411.9277 "28S ribosomal protein S6, mitochondrial OS=Homo sapiens OX=9606 GN=MRPS6 PE=1 SV=3" 9 3364.7 - 1.04E+06 - - - 0.4745 - 2.525 0.446 - 219.3 1 2 1 0.0006 10 0 0 0 4.65E+07 9.31E+06 - - - 6.2173 1 221125_WJC_METTL3_EV_vs_WT_F02.18960.18960.2 1.17E-07 15/22 R.MSVDAVEIETLR[166.11].K "sp|P78347|GTF2I_HUMAN,tr|A0A494C1K3|A0A494C1K3_HUMAN" 2 1371.6943 1.54 18161 18960 2 1371.697235 686.8544 General transcription factor II-I OS=Homo sapiens OX=9606 GN=GTF2I PE=1 SV=2 4.14 3365 - 980484 - - - 2.1134 - 3.123 0.6 - 1209.3 1 2 0 0.0029 12 0 0 0 3.47E+08 2.25E+08 - - - 6.4681 1 221125_WJC_METTL3_EV_vs_WT_F02.18961.18961.2 2.19E-09 16/32 K.MGGMEGPFGGGMENMGR[166.11].F "sp|P52272|HNRPM_HUMAN,tr|M0QYL3|M0QYL3_HUMAN,tr|A0A087X0X3|A0A087X0X3_HUMAN,tr|M0QZM1|M0QZM1_HUMAN" 4 1723.6814 1.4 18162 18961 2 1723.682778 862.848 Heterogeneous nuclear ribonucleoprotein M OS=Homo sapiens OX=9606 GN=HNRNPM PE=1 SV=3 4.53 3365.1 - 812277 - - - 0.7867 - 2.791 0.783 - 614.9 1 2 0 0.0014 17 0 0 0 2.10E+07 1.50E+07 - - - 7.3473 0.9897 221125_WJC_METTL3_EV_vs_WT_F02.18963.18963.2 0.177 12-Jun R.DLPSWMK[136.11].F sp|P78527|PRKDC_HUMAN 1 883.4353 0.78 18164 18963 2 883.435515 442.7249 DNA-dependent protein kinase catalytic subunit OS=Homo sapiens OX=9606 GN=PRKDC PE=1 SV=3 5.84 3365.4 - 505598 - - - 0.2151 - 1.155 0.151 - 114.3 1 2 0 0.0002 7 0 0 0 3.84E+06 4.93E+06 - - - 0.6128 0.9701 221125_WJC_METTL3_EV_vs_WT_F02.18966.18966.2 3.24E-08 24-Nov R.GLPWSC[160.03]SADEVMR[166.11].F sp|P55795|HNRH2_HUMAN 1 1516.6678 1.14 18167 18966 2 1517.665932 759.3412 Heterogeneous nuclear ribonucleoprotein H2 OS=Homo sapiens OX=9606 GN=HNRNPH2 PE=1 SV=1 4.37 3365.8 - 356825 - - - 658.1059 - 2.079 0.575 - 327.5 1 2 0 0.9981 13 0 0 0 1.45E+07 1.28E+07 - - - 4.8529 0.9999 221125_WJC_METTL3_EV_vs_WT_F02.18967.18967.3 0.000329 Aug-40 K.IEIDPQFQVVR.T sp|Q8N1N4|K2C78_HUMAN 1 1342.7245 16.99 18168 18967 3 1342.724227 448.5821 "Keratin, type II cytoskeletal 78 OS=Homo sapiens OX=9606 GN=KRT78 PE=1 SV=2" 4.37 3365.9 - 275263 - - - -0.2041 - 2.253 0.356 - 102.5 1 2 0 -0.0003 11 0 0 0 2.51E+06 1.47E+05 - - - 4.8165 0.9469 221125_WJC_METTL3_EV_vs_WT_F02.18970.18970.2 0.00597 16-Sep Y.FESFINNLR.R sp|P04264|K2C1_HUMAN 1 1138.5771 373.51 18169 18970 2 1138.579569 570.2958 "Keratin, type II cytoskeletal 1 OS=Homo sapiens OX=9606 GN=KRT1 PE=1 SV=6" 6 3366.3 - 1.74E+07 - - - 2.1615 - 1.767 0.362 - 268.1 1 1 0 0.0025 9 0 0 0 2.20E+08 5.90E+05 - - - 3.3609 0.9988 221125_WJC_METTL3_EV_vs_WT_F02.18972.18972.2 0.00798 22-Oct R.IVPGQFLAVDPK[136.11].G sp|Q15393|SF3B3_HUMAN 1 1290.7427 1.25 18171 18972 2 1290.740394 646.3786 Splicing factor 3B subunit 3 OS=Homo sapiens OX=9606 GN=SF3B3 PE=1 SV=4 5.84 3366.4 - 2.13E+06 - - - -1.8052 - 1.701 0.316 - 241.7 1 2 0 -0.0023 12 0 0 0 8.15E+07 6.51E+07 - - - 2.772 0.9998 221125_WJC_METTL3_EV_vs_WT_F02.18973.18973.2 5.81E-05 22-Dec R.ATISLSDSDLLR[166.11].L "sp|Q7L2E3|DHX30_HUMAN,tr|H7BXY3|H7BXY3_HUMAN" 2 1299.691 0.82 18172 18973 2 1299.69276 650.8528 ATP-dependent RNA helicase DHX30 OS=Homo sapiens OX=9606 GN=DHX30 PE=1 SV=1 4.21 3366.5 - 1.95E+06 - - - 1.3803 - 2.456 0.476 - 571.6 1 2 0 0.0018 12 0 0 0 9.64E+06 1.17E+07 - - - 4.9204 0.9998 221125_WJC_METTL3_EV_vs_WT_F02.18974.18974.2 0.00011 20-Nov K.SVQQTVELLTR.K "sp|Q9H944|MED20_HUMAN,tr|A0A804HK38|A0A804HK38_HUMAN,tr|B7ZBQ1|B7ZBQ1_HUMAN,tr|A6PVP4|A6PVP4_HUMAN,tr|B7ZBQ3|B7ZBQ3_HUMAN" 5 1272.7038 1.69 18173 18974 2 1272.705585 637.3592 Mediator of RNA polymerase II transcription subunit 20 OS=Homo sapiens OX=9606 GN=MED20 PE=1 SV=1 5.72 3366.5 - 1.64E+06 - - - 1.43 - 2.331 0.52 - 536.2 1 2 0 0.0018 11 0 0 0 7.17E+06 4.25E+06 - - - 5.1706 1 221125_WJC_METTL3_EV_vs_WT_F02.18975.18975.2 5.71E-07 15/28 R.DASLMVTNDGATILK.N "sp|P78371|TCPB_HUMAN,tr|F8VQ14|F8VQ14_HUMAN,tr|F5GWF6|F5GWF6_HUMAN" 3 1547.7865 0.46 18174 18975 2 1547.787444 774.9005 T-complex protein 1 subunit beta OS=Homo sapiens OX=9606 GN=CCT2 PE=1 SV=4 4.21 3366.7 - 1.44E+06 - - - 0.6041 - 2.857 0.593 - 533.2 1 2 0 0.0009 15 0 0 0 2.31E+07 4.99E+07 - - - 6.0015 0.9999 221125_WJC_METTL3_EV_vs_WT_F02.18977.18977.3 0.0107 Dec-44 K.NLLHQDAVDLFR[166.11].N "sp|P57105|SYJ2B_HUMAN,tr|A0A087X1F5|A0A087X1F5_HUMAN,tr|A0A087WYV9|A0A087WYV9_HUMAN" 3 1449.7604 1.23 18176 18977 3 1449.762169 484.2607 Synaptojanin-2-binding protein OS=Homo sapiens OX=9606 GN=SYNJ2BP PE=1 SV=2 5.21 3366.8 - 1.30E+06 - - - 1.2319 - 2.491 0.439 - 230.3 1 2 0 0.0018 12 0 0 0 1.44E+07 1.17E+07 - - - 5.9637 0.9999 221125_WJC_METTL3_EV_vs_WT_F02.18978.18978.2 3.98E-08 24-Nov R.GLPWSC[160.03]SADEVMR.F sp|P55795|HNRH2_HUMAN 1 1506.6595 1.14 18177 18978 2 1506.661218 754.337 Heterogeneous nuclear ribonucleoprotein H2 OS=Homo sapiens OX=9606 GN=HNRNPH2 PE=1 SV=1 4.37 3366.9 - 1.15E+06 - - - 1.1177 - 1.905 0.664 - 329.2 1 2 0 0.0017 13 0 0 0 1.45E+07 1.28E+07 - - - 5.5989 0.9973 221125_WJC_METTL3_EV_vs_WT_F02.18979.18979.2 0.00913 16-Oct K.LDDLVNWAR[166.11].R "sp|O75251|NDUS7_HUMAN,tr|F5H5N1|F5H5N1_HUMAN,tr|F5GXJ1|F5GXJ1_HUMAN,tr|A0A087WTI3|A0A087WTI3_HUMAN,tr|A0A087WXF6|A0A087WXF6_HUMAN" 5 1110.5697 0.92 18178 18979 2 1110.574116 556.2921 "NADH dehydrogenase [ubiquinone] iron-sulfur protein 7, mitochondrial OS=Homo sapiens OX=9606 GN=NDUFS7 PE=1 SV=3" 4.21 3367 - 1.08E+06 - - - 3.9511 - 2.006 0.347 - 356.9 1 2 0 0.0044 9 0 0 0 1.01E+07 1.09E+07 - - - 3.6165 0.9811 221125_WJC_METTL3_EV_vs_WT_F02.18980.18980.2 0.00272 18-Dec M.ALDIEIATYR.K "sp|P08670|VIME_HUMAN,sp|P14136|GFAP_HUMAN,sp|Q6KB66|K2C80_HUMAN,sp|P05787|K2C8_HUMAN,sp|P41219|PERI_HUMAN,sp|P19013|K2C4_HUMAN,sp|P04264|K2C1_HUMAN,sp|P08729|K2C7_HUMAN,tr|A0A1W2PR46|A0A1W2PR46_HUMAN,tr|H7C5W5|H7C5W5_HUMAN,tr|A0A1X7SBR3|A0A1X7SBR3_HUMAN,tr|A0A1W2PQU7|A0A1W2PQU7_HUMAN,tr|K7EJU1|K7EJU1_HUMAN,tr|A0A1X7SCE1|A0A1X7SCE1_HUMAN,tr|A0A1W2PRT3|A0A1W2PRT3_HUMAN,tr|A0A1W2PS58|A0A1W2PS58_HUMAN,tr|B0YJC5|B0YJC5_HUMAN,tr|B0YJC4|B0YJC4_HUMAN,tr|K7EPI4|K7EPI4_HUMAN,tr|K7EPT8|K7EPT8_HUMAN" 20 1163.6186 999 18179 18980 2 1163.619853 582.8166 Vimentin OS=Homo sapiens OX=9606 GN=VIM PE=1 SV=4 4.37 3367.1 - 897554 - - - 1.0433 - 2.278 0.341 - 564.2 1 1 0 0.0012 10 0 0 0 8.66E+06 0.00E+00 - - - 3.8573 0.9996 221125_WJC_METTL3_EV_vs_WT_F02.18981.18981.2 0.00159 24-Sep K.AWLVSSGC[160.03]PLQVK[136.11].K "sp|Q8IX01|SUGP2_HUMAN,tr|M0R2Z9|M0R2Z9_HUMAN,tr|M0R3F6|M0R3F6_HUMAN" 3 1451.7686 0.001 18180 18981 2 1451.770101 726.8916 SURP and G-patch domain-containing protein 2 OS=Homo sapiens OX=9606 GN=SUGP2 PE=1 SV=2 8.27 3367.3 - 844370 - - - 1.0194 - 1.93 0.369 - 203 1 2 0 0.0015 13 0 0 0 0.00E+00 4.99E+06 - - - 3.4535 0.9999 221125_WJC_METTL3_EV_vs_WT_F02.18982.18982.2 5.06E-06 15/30 K.LGPQASSQVVMPPLVR.G sp|Q86YP4|P66A_HUMAN 1 1677.9236 1.45 18181 18982 2 1677.923249 839.9691 Transcriptional repressor p66-alpha OS=Homo sapiens OX=9606 GN=GATAD2A PE=1 SV=1 9.75 3367.4 - 790564 - - - -0.2157 - 2.497 0.544 - 422.9 1 2 0 -0.0004 16 0 0 0 1.84E+07 1.27E+07 - - - 5.3087 0.9999 221125_WJC_METTL3_EV_vs_WT_F02.18983.18983.3 0.000198 13/44 R.MSVDAVEIETLR.K "sp|P78347|GTF2I_HUMAN,tr|A0A494C1K3|A0A494C1K3_HUMAN" 2 1361.6861 1.14 18182 18983 3 1361.686286 454.9026 General transcription factor II-I OS=Homo sapiens OX=9606 GN=GTF2I PE=1 SV=2 4.14 3367.5 - 783588 - - - 0.1616 - 2.227 0.434 - 319.2 1 2 0 0.0002 12 0 0 0 2.18E+07 1.91E+07 - - - 5.5979 0.9997 221125_WJC_METTL3_EV_vs_WT_F02.18984.18984.3 0.0154 Dec-48 R.LSMWDR[166.11]PDDLIGR[166.11].A "sp|O14776|TCRG1_HUMAN,tr|A0A7P0T8N8|A0A7P0T8N8_HUMAN,tr|G3V220|G3V220_HUMAN" 3 1592.7884 0.43 18183 18984 3 1592.790546 531.9367 Transcription elongation regulator 1 OS=Homo sapiens OX=9606 GN=TCERG1 PE=1 SV=2 4.43 3367.6 - 639403 - - - 1.3461 - 2.292 0.318 - 214.7 1 2 0 0.0021 13 0 0 0 1.74E+06 4.06E+06 - - - 4.3336 0.9998 221125_WJC_METTL3_EV_vs_WT_F02.18986.18986.2 1.46E-06 14/30 K.LGPQASSQVVMPPLVR[166.11].G sp|Q86YP4|P66A_HUMAN 1 1687.9319 1.51 18185 18986 2 1687.933177 844.9732 Transcriptional repressor p66-alpha OS=Homo sapiens OX=9606 GN=GATAD2A PE=1 SV=1 9.75 3367.9 - 514613 - - - 0.7678 - 2.255 0.444 - 169.4 1 2 0 0.0013 16 0 0 0 1.93E+07 1.27E+07 - - - 4.3191 1 221125_WJC_METTL3_EV_vs_WT_F02.18993.18993.2 1.66E-06 14/28 R.DASLMVTNDGATILK[136.11].N "sp|P78371|TCPB_HUMAN,tr|F8VQ14|F8VQ14_HUMAN,tr|F5GWF6|F5GWF6_HUMAN" 3 1555.8007 0.46 18191 18993 2 1555.800536 778.9076 T-complex protein 1 subunit beta OS=Homo sapiens OX=9606 GN=CCT2 PE=1 SV=4 4.21 3368.7 - 7.21E+06 - - - -0.1112 - 2.825 0.584 - 658.7 1 2 0 -0.0002 15 0 0 0 2.31E+07 4.99E+07 - - - 5.9076 0.9998 221125_WJC_METTL3_EV_vs_WT_F02.18994.18994.2 0.00816 18-Oct K.VVDLLAPYAK.G "sp|P06576|ATPB_HUMAN,tr|F8W079|F8W079_HUMAN,tr|H0YH81|H0YH81_HUMAN" 3 1087.6277 1.81 18192 18994 2 1087.627981 544.8211 "ATP synthase subunit beta, mitochondrial OS=Homo sapiens OX=9606 GN=ATP5F1B PE=1 SV=3" 5.81 3368.7 - 3.83E+06 - - - 0.2151 - 2 0.472 - 336.2 1 2 0 0.0002 10 0 0 0 2.12E+07 1.17E+07 - - - 4.4619 0.9629 221125_WJC_METTL3_EV_vs_WT_F02.18997.18997.2 0.992 16-Jul R.QFLTQLMQK.E sp|Q15459|SF3A1_HUMAN 1 1135.606 0.45 18195 18997 2 1135.608043 568.8103 Splicing factor 3A subunit 1 OS=Homo sapiens OX=9606 GN=SF3A1 PE=1 SV=1 8.75 3368.9 - 2.70E+06 - - - 1.8299 - 1.177 0.096 - 108.6 1 2 0 0.0021 9 0 0 0 1.99E+07 4.40E+07 - - - 0.2209 0.8895 221125_WJC_METTL3_EV_vs_WT_F02.19001.19001.2 0.0373 18-Aug R.EYLAQLSNNV.R "sp|Q8NDZ4|DIK2A_HUMAN,tr|E7ET39|E7ET39_HUMAN" 2 1149.5666 - 18199 19001 2 1149.567063 575.7906 Divergent protein kinase domain 2A OS=Homo sapiens OX=9606 GN=DIPK2A PE=1 SV=1 4 3369.2 - 1.39E+06 - - - 0.4002 - 1.128 0.33 - 123.4 1 1 0 0.0005 10 0 0 0 - - - - - 1.8144 1 221125_WJC_METTL3_EV_vs_WT_F02.19002.19002.2 7.78E-07 13/20 K.NAVEEYVYEMR[166.11].D "sp|P34932|HSP74_HUMAN,tr|A0A087WYC1|A0A087WYC1_HUMAN" 2 1411.6317 0.09 18200 19002 2 1411.629941 706.8231 Heat shock 70 kDa protein 4 OS=Homo sapiens OX=9606 GN=HSPA4 PE=1 SV=4 4.25 3369.2 - 1.20E+06 - - - -1.2716 - 2.799 0.584 - 895.2 1 2 0 -0.0018 11 0 0 0 1.09E+07 1.17E+08 - - - 6.1383 0.9998 221125_WJC_METTL3_EV_vs_WT_F02.19003.19003.2 3.03E-05 22-Dec K.QLYQTLTDYDIR.F "sp|P68400|CSK21_HUMAN,sp|Q8NEV1|CSK23_HUMAN,tr|A0A2R8YFU2|A0A2R8YFU2_HUMAN,tr|V9GYA2|V9GYA2_HUMAN,tr|A0A2R8Y4D6|A0A2R8Y4D6_HUMAN,tr|A0A2R8YD58|A0A2R8YD58_HUMAN,tr|A0A2R8YF43|A0A2R8YF43_HUMAN,tr|A0A2R8Y5A0|A0A2R8Y5A0_HUMAN,tr|A0A2R8YDY7|A0A2R8YDY7_HUMAN,tr|A0A2R8Y4H0|A0A2R8Y4H0_HUMAN,tr|E7EU96|E7EU96_HUMAN" 11 1527.7569 0.67 18201 19003 2 1527.758309 764.8857 Casein kinase II subunit alpha OS=Homo sapiens OX=9606 GN=CSNK2A1 PE=1 SV=1 4.21 3369.4 - 1.11E+06 - - - 0.9072 - 2.109 0.44 - 467.1 1 2 0 0.0014 12 0 0 0 6.40E+06 9.49E+06 - - - 4.2538 0.9998 221125_WJC_METTL3_EV_vs_WT_F02.19004.19004.2 1.45E-05 24-Dec R.LPPGFNDVDALC[160.03]R.A "sp|Q8IY67|RAVR1_HUMAN,tr|E9PAU2|E9PAU2_HUMAN,tr|A0A087WZ13|A0A087WZ13_HUMAN" 3 1472.7082 1.56 18202 19004 2 1472.706733 737.3614 Ribonucleoprotein PTB-binding 1 OS=Homo sapiens OX=9606 GN=RAVER1 PE=1 SV=1 4.21 3369.5 - 1.01E+06 - - - -0.9954 - 1.747 0.549 - 336.5 1 2 0 -0.0015 13 0 0 0 8.72E+06 5.60E+06 - - - 4.5273 1 221125_WJC_METTL3_EV_vs_WT_F02.19005.19005.3 6.51E-05 13/48 R.LVSGWVK[136.11]PIIIGR[166.11].H "sp|O75874|IDHC_HUMAN,tr|C9J4N6|C9J4N6_HUMAN" 2 1454.9092 1.83 18203 19005 3 1454.909704 485.977 Isocitrate dehydrogenase [NADP] cytoplasmic OS=Homo sapiens OX=9606 GN=IDH1 PE=1 SV=2 11 3369.6 - 992931 - - - 0.3285 - 2.586 0.505 - 213 1 2 0 0.0005 13 0 0 0 7.52E+06 4.10E+06 - - - 6.7461 0.9998 221125_WJC_METTL3_EV_vs_WT_F02.19007.19007.2 1.87E-05 22-Oct K.YLLADC[160.03]NEAFIK[136.11].L "sp|O60216|RAD21_HUMAN,tr|E5RJW1|E5RJW1_HUMAN,tr|E5RFV8|E5RFV8_HUMAN,tr|E5RJK5|E5RJK5_HUMAN,tr|E5RIN7|E5RIN7_HUMAN" 5 1463.721 0.73 18205 19007 2 1463.720106 732.8678 Double-strand-break repair protein rad21 homolog OS=Homo sapiens OX=9606 GN=RAD21 PE=1 SV=2 4.37 3369.9 - 873826 - - - -0.6121 - 1.93 0.496 - 256.6 1 2 0 -0.0009 12 0 0 0 5.38E+06 7.35E+06 - - - 4.4342 0.9997 221125_WJC_METTL3_EV_vs_WT_F02.19014.19014.2 0.0213 18-Oct K.GIYFADMVSK.S "sp|P09874|PARP1_HUMAN,tr|A0A7I2V3E1|A0A7I2V3E1_HUMAN" 2 1129.5478 0.79 18211 19014 2 1129.547484 565.7812 Poly [ADP-ribose] polymerase 1 OS=Homo sapiens OX=9606 GN=PARP1 PE=1 SV=4 5.83 3370.6 - 5.76E+06 - - - -0.2638 - 1.804 0.41 - 263.4 1 2 0 -0.0003 10 0 0 0 6.74E+07 8.57E+07 - - - 3.7161 0.9636 221125_WJC_METTL3_EV_vs_WT_F02.19017.19017.2 0.0047 24-Sep W.QEGQGGTEEEEK[136.11]R.R tr|H0YJM3|H0YJM3_HUMAN 1 1483.663 - 18214 19017 2 1483.664264 742.8388 Cellular oncogene fos (Fragment) OS=Homo sapiens OX=9606 GN=FOS PE=3 SV=1 4.33 3370.8 - 2.30E+06 - - - 0.8324 - 1.738 0.344 - 257.8 1 1 0 0.0012 13 0 0 0 - - - - - 3 0.9997 221125_WJC_METTL3_EV_vs_WT_F02.19020.19020.2 0.0147 18-Oct K.GYGFVSFYNK.L "sp|Q01085|TIAR_HUMAN,tr|E7ETJ9|E7ETJ9_HUMAN" 2 1180.5553 1.67 18217 19020 2 1180.553831 591.2849 Nucleolysin TIAR OS=Homo sapiens OX=9606 GN=TIAL1 PE=1 SV=1 8.5 3371.1 - 1.35E+06 - - - -1.2528 - 1.937 0.418 - 337.4 1 2 0 -0.0015 10 0 0 0 4.22E+07 2.52E+07 - - - 3.9733 1 221125_WJC_METTL3_EV_vs_WT_F02.19021.19021.3 7.44E-06 15/60 R.AVGSVTVYYEVAGHLR.T sp|Q8TEM1|PO210_HUMAN 1 1719.8944 3.14 18218 19021 3 1719.894121 574.3054 Nuclear pore membrane glycoprotein 210 OS=Homo sapiens OX=9606 GN=NUP210 PE=1 SV=3 6.79 3371.2 - 1.20E+06 - - - -0.1738 - 2.703 0.548 - 254.1 1 2 0 -0.0003 16 0 0 0 6.34E+06 2.02E+06 - - - 7.201 0.7939 221125_WJC_METTL3_EV_vs_WT_F02.19022.19022.2 1.02 12-Jul F.AFISFHR.R "sp|O75821|EIF3G_HUMAN,tr|K7EP16|K7EP16_HUMAN,tr|K7ENA8|K7ENA8_HUMAN" 3 876.4606 0.88 18219 19022 2 876.460507 439.2376 Eukaryotic translation initiation factor 3 subunit G OS=Homo sapiens OX=9606 GN=EIF3G PE=1 SV=2 9.8 3371.3 - 692345 - - - -0.1312 - 1.399 0.149 - 161.8 1 1 0 -0.0001 7 0 0 0 5.37E+06 6.09E+06 - - - 1.2053 0.9935 221125_WJC_METTL3_EV_vs_WT_F02.19023.19023.2 1.57E-07 14/24 L.LTTAEVVVTEIPK[136.11].E "sp|P10809|CH60_HUMAN,tr|A0A7I2V2X6|A0A7I2V2X6_HUMAN,tr|A0A7I2YQK6|A0A7I2YQK6_HUMAN" 3 1406.8112 1.42 18220 19023 2 1406.811317 704.4129 "60 kDa heat shock protein, mitochondrial OS=Homo sapiens OX=9606 GN=HSPD1 PE=1 SV=2" 4.53 3371.4 - 608370 - - - 0.0853 - 2.583 0.484 - 539.9 1 1 0 0.0001 13 0 0 0 9.83E+06 6.90E+06 - - - 5.0513 0.9999 221125_WJC_METTL3_EV_vs_WT_F02.19024.19024.2 5.89E-06 22-Dec K.QLYQTLTDYDIR[166.11].F "sp|P68400|CSK21_HUMAN,sp|Q8NEV1|CSK23_HUMAN,tr|A0A2R8YFU2|A0A2R8YFU2_HUMAN,tr|V9GYA2|V9GYA2_HUMAN,tr|A0A2R8Y4D6|A0A2R8Y4D6_HUMAN,tr|A0A2R8YD58|A0A2R8YD58_HUMAN,tr|A0A2R8YF43|A0A2R8YF43_HUMAN,tr|A0A2R8Y5A0|A0A2R8Y5A0_HUMAN,tr|A0A2R8YDY7|A0A2R8YDY7_HUMAN,tr|A0A2R8Y4H0|A0A2R8Y4H0_HUMAN,tr|E7EU96|E7EU96_HUMAN" 11 1537.7652 0.67 18221 19024 2 1537.764331 769.8899 Casein kinase II subunit alpha OS=Homo sapiens OX=9606 GN=CSNK2A1 PE=1 SV=1 4.21 3371.6 - 593009 - - - -0.5606 - 2.416 0.509 - 166.4 1 2 0 -0.0009 12 0 0 0 6.40E+06 9.49E+06 - - - 5.1212 0.9982 221125_WJC_METTL3_EV_vs_WT_F02.19025.19025.3 0.0107 Dec-56 R.DASLMVTNDGATILK[136.11].N "sp|P78371|TCPB_HUMAN,tr|F8VQ14|F8VQ14_HUMAN,tr|F5GWF6|F5GWF6_HUMAN" 3 1555.8007 0.4 18222 19025 3 1555.798998 519.6075 T-complex protein 1 subunit beta OS=Homo sapiens OX=9606 GN=CCT2 PE=1 SV=4 4.21 3371.7 - 557013 - - - -1.0998 - 1.597 0.286 - 130.2 1 2 0 -0.0017 15 0 0 0 1.07E+06 2.64E+06 - - - 2.9497 1 221125_WJC_METTL3_EV_vs_WT_F02.19030.19030.2 3.21E-08 16/26 K.LGGSAVISLEGKPL.- "sp|P23528|COF1_HUMAN,tr|G3V1A4|G3V1A4_HUMAN,tr|E9PK25|E9PK25_HUMAN" 3 1339.7711 1.36 18225 19030 2 1339.77293 670.8928 Cofilin-1 OS=Homo sapiens OX=9606 GN=CFL1 PE=1 SV=3 6 3372.2 - 7.78E+06 - - - 1.3532 - 3.03 0.536 - 693.4 1 2 0 0.0018 14 0 0 0 9.53E+08 6.99E+08 - - - 5.7812 0.9998 221125_WJC_METTL3_EV_vs_WT_F02.19031.19031.3 0.267 Oct-40 K.NAVEEYVYEMR[166.11].D "sp|P34932|HSP74_HUMAN,tr|A0A087WYC1|A0A087WYC1_HUMAN" 2 1411.6317 0.22 18226 19031 3 1411.631837 471.5512 Heat shock 70 kDa protein 4 OS=Homo sapiens OX=9606 GN=HSPA4 PE=1 SV=4 4.25 3372.3 - 3.79E+06 - - - 0.0715 - 1.961 0.354 - 111.1 1 2 0 0.0001 11 0 0 0 6.71E+06 3.09E+07 - - - 4.3999 0.9998 221125_WJC_METTL3_EV_vs_WT_F02.19032.19032.2 0.00954 13/20 K.QLSDAISIIGR[166.11].E sp|P55060|XPO2_HUMAN 1 1181.6644 0.98 18227 19032 2 1181.665203 591.8395 Exportin-2 OS=Homo sapiens OX=9606 GN=CSE1L PE=1 SV=3 5.84 3372.3 - 3.44E+06 - - - 0.7159 - 2.033 0.445 - 591.4 1 2 0 0.0008 11 0 0 0 3.57E+07 3.64E+07 - - - 4.2469 0.9999 221125_WJC_METTL3_EV_vs_WT_F02.19033.19033.2 0.0224 13/20 R.SNLGSVVLQLK[136.11].K sp|O43143|DHX15_HUMAN 1 1164.6958 0.93 18228 19033 2 1164.69538 583.3552 Pre-mRNA-splicing factor ATP-dependent RNA helicase DHX15 OS=Homo sapiens OX=9606 GN=DHX15 PE=1 SV=2 8.47 3372.4 - 3.12E+06 - - - -0.3374 - 2.562 0.426 - 541.4 1 2 0 -0.0004 11 0 0 0 7.33E+07 7.87E+07 - - - 4.7324 0.9997 221125_WJC_METTL3_EV_vs_WT_F02.19036.19036.2 1.67E-05 15/28 K.LQPLSPVPSDIEISR[166.11].G "sp|Q6UB35|C1TM_HUMAN,tr|A0A087WVM4|A0A087WVM4_HUMAN,tr|B7ZM99|B7ZM99_HUMAN,tr|H0Y327|H0Y327_HUMAN" 4 1659.9071 -1 18231 19036 2 1659.903339 830.9608 "Monofunctional C1-tetrahydrofolate synthase, mitochondrial OS=Homo sapiens OX=9606 GN=MTHFD1L PE=1 SV=1" 4.37 3372.7 - 1.27E+06 - - - -2.2694 - 2.426 0.503 - 600.4 1 2 0 -0.0038 15 0 0 0 0.00E+00 0.00E+00 - - - 4.9338 0.9998 221125_WJC_METTL3_EV_vs_WT_F02.19037.19037.2 0.00189 16-Nov R.LSNIFVIGK[136.11].G sp|P62701|RS4X_HUMAN 1 997.6052 1.04 18232 19037 2 997.606165 499.8099 "40S ribosomal protein S4, X isoform OS=Homo sapiens OX=9606 GN=RPS4X PE=1 SV=2" 8.75 3372.8 - 1.11E+06 - - - 1.0004 - 2.27 0.438 - 307 1 2 0 0.001 9 0 0 0 2.20E+08 2.12E+08 - - - 4.6474 0.9995 221125_WJC_METTL3_EV_vs_WT_F02.19038.19038.2 0.00644 16-Oct R.LSNIFVIGK.G sp|P62701|RS4X_HUMAN 1 989.591 1.04 18233 19038 2 989.593227 495.8028 "40S ribosomal protein S4, X isoform OS=Homo sapiens OX=9606 GN=RPS4X PE=1 SV=2" 8.75 3372.9 - 811021 - - - 2.2838 - 2.11 0.404 - 260.8 1 2 0 0.0023 9 0 0 0 2.20E+08 2.12E+08 - - - 4.1844 0.9986 221125_WJC_METTL3_EV_vs_WT_F02.19039.19039.2 0.149 16-Aug K.DLILPTIQK[136.11].S sp|Q92616|GCN1_HUMAN 1 1047.6419 0.66 18234 19039 2 1047.643088 524.8282 eIF-2-alpha kinase activator GCN1 OS=Homo sapiens OX=9606 GN=GCN1 PE=1 SV=6 5.84 3373 - 781777 - - - 1.0891 - 1.72 0.24 - 162.4 1 2 0 0.0011 9 0 0 0 4.58E+06 6.93E+06 - - - 2.3823 1 221125_WJC_METTL3_EV_vs_WT_F02.19040.19040.2 2.75E-09 14/26 K.NISMSVEGDYTYLR.L sp|Q9Y5B9|SP16H_HUMAN 1 1646.761 1.1 18235 19040 2 1646.758495 824.3878 FACT complex subunit SPT16 OS=Homo sapiens OX=9606 GN=SUPT16H PE=1 SV=1 4.37 3373.1 - 771737 - - - -1.5345 - 2.677 0.667 - 549.2 1 2 0 -0.0025 14 0 0 0 7.52E+06 6.85E+06 - - - 6.4377 0.9999 221125_WJC_METTL3_EV_vs_WT_F02.19041.19041.2 1.43E-05 13/24 K.LLSTGPTEPWSIR.E "sp|Q9H0E9|BRD8_HUMAN,tr|B5MCW3|B5MCW3_HUMAN,tr|H7C179|H7C179_HUMAN,tr|C9JV05|C9JV05_HUMAN,tr|F8WCS7|F8WCS7_HUMAN,tr|F8WDX5|F8WDX5_HUMAN,tr|H7C128|H7C128_HUMAN,tr|D6RID0|D6RID0_HUMAN,tr|H7C127|H7C127_HUMAN,tr|F8WBH2|F8WBH2_HUMAN" 10 1455.7722 2.03 18236 19041 2 1455.770804 728.8934 Bromodomain-containing protein 8 OS=Homo sapiens OX=9606 GN=BRD8 PE=1 SV=2 6 3373.3 - 719933 - - - -0.9445 - 2.413 0.497 - 649.5 1 2 0 -0.0014 13 0 0 0 9.47E+06 4.67E+06 - - - 4.9722 0.766 221125_WJC_METTL3_EV_vs_WT_F02.19043.19043.2 0.985 16-Aug K.SIFKEVEEK.E sp|Q2NL82|TSR1_HUMAN 1 1107.5812 1.6 18238 19043 2 1107.58084 554.7979 Pre-rRNA-processing protein TSR1 homolog OS=Homo sapiens OX=9606 GN=TSR1 PE=1 SV=1 4.78 3373.5 - 578713 - - - -0.3169 - 1.234 0.044 - 153.5 1 2 1 -0.0004 9 0 0 0 1.05E+07 6.53E+06 - - - -0.0258 0.9984 221125_WJC_METTL3_EV_vs_WT_F02.19044.19044.2 2.88E-07 28-Dec K.VLGTSVESIMATEDR.Q "sp|P31327|CPSM_HUMAN,tr|A0A669KBF2|A0A669KBF2_HUMAN" 2 1606.7872 2.95 18239 19044 2 1606.779242 804.4009 "Carbamoyl-phosphate synthase [ammonia], mitochondrial OS=Homo sapiens OX=9606 GN=CPS1 PE=1 SV=2" 4.14 3373.7 - 570941 - - - -4.9758 - 2.4 0.591 - 449.8 1 2 0 -0.008 15 0 0 0 4.15E+06 1.41E+06 - - - 5.556 0.997 221125_WJC_METTL3_EV_vs_WT_F02.19047.19047.3 0.258 Oct-36 R.MGFFLSLHQR[166.11].G "sp|Q9Y312|AAR2_HUMAN,tr|A0A7P0T8J7|A0A7P0T8J7_HUMAN,tr|A0A7P0TA70|A0A7P0TA70_HUMAN,tr|A2A2Q9|A2A2Q9_HUMAN" 4 1244.6364 0.29 18242 19047 3 1244.636669 415.8861 Protein AAR2 homolog OS=Homo sapiens OX=9606 GN=AAR2 PE=1 SV=2 9.52 3374 - 353623 - - - 0.2418 - 1.774 0.211 - 81.5 1 2 0 0.0003 10 0 0 0 5.63E+05 1.94E+06 - - - 2.5665 0.9998 221125_WJC_METTL3_EV_vs_WT_F02.19049.19049.2 5.36E-05 13/20 R.TDLEMQIEGLK.E "sp|P08727|K1C19_HUMAN,sp|P08779|K1C16_HUMAN,tr|C9JM50|C9JM50_HUMAN,tr|K7EMS3|K7EMS3_HUMAN" 4 1275.6381 999 18243 19049 2 1275.638717 638.8263 "Keratin, type I cytoskeletal 19 OS=Homo sapiens OX=9606 GN=KRT19 PE=1 SV=4" 4.14 3374.3 - 3.62E+07 - - - 0.5197 - 2.709 0.371 - 760.5 1 2 0 0.0007 11 0 0 0 2.45E+08 0.00E+00 - - - 4.477 0.9673 221125_WJC_METTL3_EV_vs_WT_F02.19050.19050.2 0.234 20-Aug R.EAMGIYISTLK[136.11].T "sp|O95433|AHSA1_HUMAN,tr|H0YJU2|H0YJU2_HUMAN,tr|G3V438|G3V438_HUMAN,tr|H0YJG7|H0YJG7_HUMAN" 4 1232.6566 1.12 18244 19050 2 1232.657809 617.3356 Activator of 90 kDa heat shock protein ATPase homolog 1 OS=Homo sapiens OX=9606 GN=AHSA1 PE=1 SV=1 6.1 3374.3 - 1.42E+06 - - - 0.9719 - 1.257 0.047 - 157.8 1 2 0 0.0012 11 0 0 0 3.20E+07 2.85E+07 - - - 0.0065 0.9999 221125_WJC_METTL3_EV_vs_WT_F02.19051.19051.2 0.0011 13/26 K.LGGSAVISLEGK[136.11]PL.- "sp|P23528|COF1_HUMAN,tr|G3V1A4|G3V1A4_HUMAN,tr|E9PK25|E9PK25_HUMAN" 3 1347.7853 1.37 18245 19051 2 1347.785962 674.8999 Cofilin-1 OS=Homo sapiens OX=9606 GN=CFL1 PE=1 SV=3 6 3374.4 - 1.59E+07 - - - 0.4786 - 2.375 0.509 - 467.1 1 2 0 0.0006 14 0 0 0 9.56E+08 7.00E+08 - - - 4.9709 0.9978 221125_WJC_METTL3_EV_vs_WT_F02.19052.19052.2 0.168 12-Jun R.DFYFSVK[136.11].L sp|Q9NY12|GAR1_HUMAN 1 912.4473 0.98 18246 19052 2 912.446941 457.2309 H\ACA ribonucleoprotein complex subunit 1 OS=Homo sapiens OX=9606 GN=GAR1 PE=1 SV=1 5.83 3374.4 - 7.51E+06 - - - -0.3606 - 1.205 0.281 - 151.5 1 2 0 -0.0003 7 0 0 0 8.09E+07 8.29E+07 - - - 1.7072 0.9999 221125_WJC_METTL3_EV_vs_WT_F02.19053.19053.2 0.002 20-Dec R.SNLGSVVLQLK.K sp|O43143|DHX15_HUMAN 1 1156.6816 0.93 18247 19053 2 1156.681639 579.3481 Pre-mRNA-splicing factor ATP-dependent RNA helicase DHX15 OS=Homo sapiens OX=9606 GN=DHX15 PE=1 SV=2 8.47 3374.4 - 6.72E+06 - - - 0.0571 - 2.448 0.504 - 458.3 1 2 0 0.0001 11 0 0 0 7.33E+07 7.87E+07 - - - 5.1854 0.9998 221125_WJC_METTL3_EV_vs_WT_F02.19055.19055.2 3.57E-05 24-Nov K.VIPTFVTENNVIK.S sp|O43303|CP110_HUMAN 1 1472.8239 1.31 18249 19055 2 1472.823175 737.4192 Centriolar coiled-coil protein of 110 kDa OS=Homo sapiens OX=9606 GN=CCP110 PE=1 SV=3 5.97 3374.6 - 1.54E+06 - - - -0.4794 - 1.954 0.46 - 408 1 2 0 -0.0007 13 0 0 0 9.56E+06 7.29E+06 - - - 4.1576 0.9999 221125_WJC_METTL3_EV_vs_WT_F02.19056.19056.2 9.63E-05 20-Oct R.AMLDQLMGTSR[166.11].D "sp|Q9Y383|LC7L2_HUMAN,tr|F8WEU3|F8WEU3_HUMAN,tr|V9GZ75|V9GZ75_HUMAN" 3 1231.5928 0.98 18250 19056 2 1231.592665 616.8037 Putative RNA-binding protein Luc7-like 2 OS=Homo sapiens OX=9606 GN=LUC7L2 PE=1 SV=2 5.88 3374.7 - 1.42E+06 - - - -0.1486 - 2.16 0.481 - 432.4 1 2 0 -0.0002 11 0 0 0 1.31E+07 1.34E+07 - - - 4.6769 1 221125_WJC_METTL3_EV_vs_WT_F02.19057.19057.2 6.94E-08 13/20 K.NAVEEYVYEMR.D "sp|P34932|HSP74_HUMAN,tr|A0A087WYC1|A0A087WYC1_HUMAN" 2 1401.6235 0.08 18251 19057 2 1401.619337 701.819 Heat shock 70 kDa protein 4 OS=Homo sapiens OX=9606 GN=HSPA4 PE=1 SV=4 4.25 3374.8 - 1.42E+06 - - - -2.9459 - 2.762 0.582 - 910 1 2 0 -0.0041 11 0 0 0 9.01E+06 1.17E+08 - - - 6.0868 0.9998 221125_WJC_METTL3_EV_vs_WT_F02.19058.19058.2 0.000165 14-Sep K.DIEDVFYK[136.11].Y "sp|Q07955|SRSF1_HUMAN,tr|J3QQV5|J3QQV5_HUMAN,tr|J3KTL2|J3KTL2_HUMAN,tr|J3KSW7|J3KSW7_HUMAN" 4 1035.5004 0.09 18252 19058 2 1035.5005 518.7575 Serine\arginine-rich splicing factor 1 OS=Homo sapiens OX=9606 GN=SRSF1 PE=1 SV=2 4.03 3374.9 - 1.08E+06 - - - 0.0705 - 1.648 0.471 - 219.6 1 2 0 0.0001 8 0 0 0 2.20E+07 2.38E+08 - - - 4.0264 0.997 221125_WJC_METTL3_EV_vs_WT_F02.19059.19059.2 0.0258 16-Sep R.DVELLYPVK[136.11].E sp|P07099|HYEP_HUMAN 1 1082.6103 0.57 18253 19059 2 1082.612653 542.3124 Epoxide hydrolase 1 OS=Homo sapiens OX=9606 GN=EPHX1 PE=1 SV=1 4.37 3375.1 - 1.03E+06 - - - 2.1624 - 1.561 0.26 - 204.6 1 2 0 0.0023 9 0 0 0 4.73E+06 8.25E+06 - - - 2.249 0.9999 221125_WJC_METTL3_EV_vs_WT_F02.19060.19060.2 2.07E-05 24-Dec K.LLSTGPTEPWSIR[166.11].E "sp|Q9H0E9|BRD8_HUMAN,tr|B5MCW3|B5MCW3_HUMAN,tr|H7C179|H7C179_HUMAN,tr|C9JV05|C9JV05_HUMAN,tr|F8WCS7|F8WCS7_HUMAN,tr|F8WDX5|F8WDX5_HUMAN,tr|H7C128|H7C128_HUMAN,tr|D6RID0|D6RID0_HUMAN,tr|H7C127|H7C127_HUMAN,tr|F8WBH2|F8WBH2_HUMAN" 10 1465.7804 2 18254 19060 2 1465.780638 733.8975 Bromodomain-containing protein 8 OS=Homo sapiens OX=9606 GN=BRD8 PE=1 SV=2 6 3375.2 - 975473 - - - 0.1289 - 2.301 0.501 - 569.6 1 2 0 0.0002 13 0 0 0 9.31E+06 4.67E+06 - - - 4.8801 0.9977 221125_WJC_METTL3_EV_vs_WT_F02.19061.19061.2 0.000354 20-Aug K.LLTQGFTNWTK.R "sp|P28370|SMCA1_HUMAN,tr|A0A0A0MRP6|A0A0A0MRP6_HUMAN,tr|B7ZLQ5|B7ZLQ5_HUMAN" 3 1307.6874 0.45 18255 19061 2 1307.692825 654.851 Probable global transcription activator SNF2L1 OS=Homo sapiens OX=9606 GN=SMARCA1 PE=1 SV=2 8.75 3375.3 - 761661 - - - 4.1585 - 1.837 0.449 - 162.7 1 2 0 0.0054 11 0 0 0 3.74E+06 8.25E+06 - - - 4.0008 1 221125_WJC_METTL3_EV_vs_WT_F02.19062.19062.2 1.26E-09 16/32 K.VAFGSLAANGPTTLVDK[136.11].V sp|Q9UKX7|NUP50_HUMAN 1 1667.8974 0.84 18256 19062 2 1667.898013 834.956 Nuclear pore complex protein Nup50 OS=Homo sapiens OX=9606 GN=NUP50 PE=1 SV=2 5.81 3375.5 - 621141 - - - 0.3759 - 3.329 0.536 - 766.5 1 2 0 0.0006 17 0 0 0 3.33E+07 3.96E+07 - - - 5.9565 0.979 221125_WJC_METTL3_EV_vs_WT_F02.19063.19063.2 0.545 16-Sep K.DLILPTIQK.S sp|Q92616|GCN1_HUMAN 1 1039.6277 0.66 18257 19063 2 1039.631488 520.8211 eIF-2-alpha kinase activator GCN1 OS=Homo sapiens OX=9606 GN=GCN1 PE=1 SV=6 5.84 3375.6 - 670144 - - - 3.5984 - 1.299 0.227 - 142 1 2 0 0.0037 9 0 0 0 4.58E+06 6.93E+06 - - - 1.4733 0.9998 221125_WJC_METTL3_EV_vs_WT_F02.19067.19067.2 1.36E-06 18-Sep K.GIYFADMVSK[136.11].S "sp|P09874|PARP1_HUMAN,tr|A0A7I2V3E1|A0A7I2V3E1_HUMAN" 2 1137.562 0.78 18259 19067 2 1137.562674 569.7883 Poly [ADP-ribose] polymerase 1 OS=Homo sapiens OX=9606 GN=PARP1 PE=1 SV=4 5.83 3376.1 - 9.31E+06 - - - 0.6083 - 1.842 0.479 - 195.8 1 2 0 0.0007 10 0 0 0 6.74E+07 8.67E+07 - - - 4.2838 0.9609 221125_WJC_METTL3_EV_vs_WT_F02.19068.19068.2 0.342 12-Jun R.DFYFSVK.L sp|Q9NY12|GAR1_HUMAN 1 904.4331 0.98 18260 19068 2 904.436778 453.2238 H\ACA ribonucleoprotein complex subunit 1 OS=Homo sapiens OX=9606 GN=GAR1 PE=1 SV=1 5.83 3376.1 - 1.18E+07 - - - 4.0998 - 1.133 0.249 - 148.9 1 2 0 0.0037 7 0 0 0 8.02E+07 8.21E+07 - - - 1.2746 0.9998 221125_WJC_METTL3_EV_vs_WT_F02.19070.19070.2 1.34E-05 18-Oct R.NVEMFMNIEK.T sp|Q92922|SMRC1_HUMAN 1 1253.5784 1.71 18262 19070 2 1253.579358 627.7965 SWI\SNF complex subunit SMARCC1 OS=Homo sapiens OX=9606 GN=SMARCC1 PE=1 SV=3 4.53 3376.2 - 2.07E+06 - - - 0.7403 - 2.071 0.43 - 274.9 1 2 0 0.0009 10 0 0 0 1.85E+07 1.09E+07 - - - 4.2488 0.9999 221125_WJC_METTL3_EV_vs_WT_F02.19071.19071.2 4.63E-07 24-Dec R.ESLVVNYEDLAAR.E "sp|P49736|MCM2_HUMAN,tr|H0Y8E6|H0Y8E6_HUMAN" 2 1477.7413 1.76 18263 19071 2 1477.740574 739.8779 DNA replication licensing factor MCM2 OS=Homo sapiens OX=9606 GN=MCM2 PE=1 SV=4 4.14 3376.4 - 1.43E+06 - - - -0.473 - 2.528 0.542 - 481.7 1 2 0 -0.0007 13 0 0 0 1.15E+07 6.53E+06 - - - 5.4243 0.9805 221125_WJC_METTL3_EV_vs_WT_F02.19073.19073.2 1.32E-05 24-Nov R.ESLVVNYEDLAAR[166.11].E "sp|P49736|MCM2_HUMAN,tr|H0Y8E6|H0Y8E6_HUMAN" 2 1487.7495 1.71 18265 19073 2 1488.756996 744.882 DNA replication licensing factor MCM2 OS=Homo sapiens OX=9606 GN=MCM2 PE=1 SV=4 4.14 3376.5 - 1.32E+06 - - - 677.1657 - 2.399 0.518 - 437.3 1 2 0 1.0075 13 0 0 0 1.11E+07 6.53E+06 - - - 4.7965 0.9998 221125_WJC_METTL3_EV_vs_WT_F02.19076.19076.2 0.00113 13/28 K.LQPLSPVPSDIEISR.G "sp|Q6UB35|C1TM_HUMAN,tr|A0A087WVM4|A0A087WVM4_HUMAN,tr|B7ZM99|B7ZM99_HUMAN,tr|H0Y327|H0Y327_HUMAN" 4 1649.8988 2.49 18268 19076 2 1649.900477 825.9567 "Monofunctional C1-tetrahydrofolate synthase, mitochondrial OS=Homo sapiens OX=9606 GN=MTHFD1L PE=1 SV=1" 4.37 3376.8 - 964238 - - - 0.9946 - 2.248 0.487 - 471.3 1 2 0 0.0016 15 0 0 0 8.08E+06 3.25E+06 - - - 4.629 0.9963 221125_WJC_METTL3_EV_vs_WT_F02.19077.19077.2 9.71E-06 13/20 K.IEELQLIVNDK[136.11].S "sp|P62195|PRS8_HUMAN,tr|J3QQM1|J3QQM1_HUMAN,tr|J3KRP2|J3KRP2_HUMAN,tr|J3QSA9|J3QSA9_HUMAN,tr|J3QLH6|J3QLH6_HUMAN,tr|J3QSE0|J3QSE0_HUMAN" 6 1320.738 1.09 18269 19077 2 1320.74574 661.3763 26S proteasome regulatory subunit 8 OS=Homo sapiens OX=9606 GN=PSMC5 PE=1 SV=1 4.14 3376.9 - 884629 - - - 5.8361 - 2.761 0.448 - 665.8 1 2 0 0.0077 11 0 0 0 4.51E+07 4.14E+07 - - - 5.0949 0.9923 221125_WJC_METTL3_EV_vs_WT_F02.19078.19078.2 0.00052 18-Aug R.NVEMFMNIEK[136.11].T sp|Q92922|SMRC1_HUMAN 1 1261.5926 1.82 18270 19078 2 1261.586397 631.8036 SWI\SNF complex subunit SMARCC1 OS=Homo sapiens OX=9606 GN=SMARCC1 PE=1 SV=3 4.53 3377 - 872893 - - - -4.9406 - 1.442 0.426 - 146.8 1 2 0 -0.0062 10 0 0 0 1.85E+07 1.02E+07 - - - 3.2072 0.9864 221125_WJC_METTL3_EV_vs_WT_F02.19085.19085.2 0.000247 14-Aug L.WGSQDLFR.L tr|M0R344|M0R344_HUMAN 1 1007.4825 1.42 18276 19085 2 1007.482969 504.7485 Sphingosine kinase 2 OS=Homo sapiens OX=9606 GN=SPHK2 PE=1 SV=1 5.84 3377.8 - 6.27E+06 - - - 0.4864 - 1.905 0.409 - 419.3 1 1 0 0.0005 8 0 0 0 5.47E+07 3.84E+07 - - - 4.0054 0.9866 221125_WJC_METTL3_EV_vs_WT_F02.19088.19088.2 0.000122 14-Aug L.WGSQDLFR[166.11].L tr|M0R344|M0R344_HUMAN 1 1017.4907 1.42 18279 19088 2 1017.490737 509.7527 Sphingosine kinase 2 OS=Homo sapiens OX=9606 GN=SPHK2 PE=1 SV=1 5.84 3378 - 3.97E+06 - - - -0.0118 - 1.886 0.401 - 421 1 1 0 0 8 0 0 0 5.47E+07 3.84E+07 - - - 3.9163 0.9789 221125_WJC_METTL3_EV_vs_WT_F02.19089.19089.2 0.000169 30-Aug K.SINPDEAVAYGAAVQA.A "sp|P54652|HSP72_HUMAN,sp|P0DMV8|HS71A_HUMAN,sp|P34931|HS71L_HUMAN,sp|P11142|HSP7C_HUMAN,sp|P0DMV9|HS71B_HUMAN,sp|P17066|HSP76_HUMAN,tr|E9PNE6|E9PNE6_HUMAN,tr|A8K7Q2|A8K7Q2_HUMAN,tr|E9PKE3|E9PKE3_HUMAN,tr|Q53FA3|Q53FA3_HUMAN,tr|V9GZ37|V9GZ37_HUMAN,tr|A0A0G2JIW1|A0A0G2JIW1_HUMAN" 12 1574.7577 - 18280 19089 2 1574.755791 788.3861 Heat shock-related 70 kDa protein 2 OS=Homo sapiens OX=9606 GN=HSPA2 PE=1 SV=1 3.67 3378 - 3.21E+06 - - - -1.1811 - 1.663 0.458 - 103.8 1 1 0 -0.0019 16 0 0 0 - - - - - 3.6737 0.9999 221125_WJC_METTL3_EV_vs_WT_F02.19091.19091.2 1.13E-06 18-Nov K.GYGFVSFYNK[136.11].L "sp|Q01085|TIAR_HUMAN,tr|E7ETJ9|E7ETJ9_HUMAN" 2 1188.5695 1.73 18282 19091 2 1188.568484 595.292 Nucleolysin TIAR OS=Homo sapiens OX=9606 GN=TIAL1 PE=1 SV=1 8.5 3378.1 - 2.36E+06 - - - -0.8632 - 2.293 0.579 - 398.9 1 2 0 -0.001 10 0 0 0 4.34E+07 2.51E+07 - - - 5.6336 0.9997 221125_WJC_METTL3_EV_vs_WT_F02.19092.19092.2 0.0117 20-Dec K.IEELQLIVNDK.S "sp|P62195|PRS8_HUMAN,tr|J3QQM1|J3QQM1_HUMAN,tr|J3KRP2|J3KRP2_HUMAN,tr|J3QSA9|J3QSA9_HUMAN,tr|J3QLH6|J3QLH6_HUMAN,tr|J3QSE0|J3QSE0_HUMAN" 6 1312.7238 1.14 18283 19092 2 1312.725597 657.3692 26S proteasome regulatory subunit 8 OS=Homo sapiens OX=9606 GN=PSMC5 PE=1 SV=1 4.14 3378.2 - 2.07E+06 - - - 1.3445 - 2.62 0.327 - 614.4 1 2 0 0.0018 11 0 0 0 4.71E+07 4.14E+07 - - - 4.0613 0.9997 221125_WJC_METTL3_EV_vs_WT_F02.19093.19093.2 0.000429 14-Sep R.LNVWDLSK.L "sp|Q09028|RBBP4_HUMAN,sp|Q16576|RBBP7_HUMAN,tr|H0YCT5|H0YCT5_HUMAN,tr|H0YDK2|H0YDK2_HUMAN,tr|Q5JP02|Q5JP02_HUMAN,tr|H0YEU5|H0YEU5_HUMAN,tr|Q5JNZ6|Q5JNZ6_HUMAN,tr|H0YF10|H0YF10_HUMAN,tr|E9PC52|E9PC52_HUMAN" 9 973.5233 1.56 18284 19093 2 973.523281 487.7689 Histone-binding protein RBBP4 OS=Homo sapiens OX=9606 GN=RBBP4 PE=1 SV=3 5.84 3378.3 - 1.85E+06 - - - -0.001 - 1.889 0.345 - 272.8 1 2 0 0 8 0 0 0 2.93E+08 1.88E+08 - - - 3.5075 0.9952 221125_WJC_METTL3_EV_vs_WT_F02.19095.19095.2 2.46E-05 24-Dec R.ESLVVNYEDLAAR[166.11].E "sp|P49736|MCM2_HUMAN,tr|H0Y8E6|H0Y8E6_HUMAN" 2 1487.7495 1.71 18286 19095 2 1487.740487 744.882 DNA replication licensing factor MCM2 OS=Homo sapiens OX=9606 GN=MCM2 PE=1 SV=4 4.14 3378.4 - 1.40E+06 - - - -6.087 - 2.247 0.514 - 508.4 1 2 0 -0.0091 13 0 0 0 1.11E+07 6.53E+06 - - - 4.9124 0.9997 221125_WJC_METTL3_EV_vs_WT_F02.19097.19097.2 5.63E-07 16-Nov K.THILLFLPK.S "sp|P07237|PDIA1_HUMAN,tr|A0A7P0TA97|A0A7P0TA97_HUMAN,tr|A0A7P0T8C0|A0A7P0T8C0_HUMAN,tr|H7BZ94|H7BZ94_HUMAN,tr|A0A7P0TA71|A0A7P0TA71_HUMAN,tr|I3L4M2|I3L4M2_HUMAN,tr|A0A7P0T9D6|A0A7P0T9D6_HUMAN,tr|A0A7P0T9K9|A0A7P0T9K9_HUMAN,tr|H0Y3Z3|H0Y3Z3_HUMAN,tr|A0A7P0TA35|A0A7P0TA35_HUMAN,tr|I3L514|I3L514_HUMAN,tr|A0A7P0TB26|A0A7P0TB26_HUMAN,tr|A0A7P0T9U6|A0A7P0T9U6_HUMAN,tr|I3L3P5|I3L3P5_HUMAN,tr|A0A7P0T8X1|A0A7P0T8X1_HUMAN" 15 1080.6696 1.44 18288 19097 2 1080.669041 541.3421 Protein disulfide-isomerase OS=Homo sapiens OX=9606 GN=P4HB PE=1 SV=3 8.44 3378.7 - 901064 - - - -0.4729 - 2.188 0.288 - 503.4 1 2 0 -0.0005 9 0 0 0 3.71E+07 2.57E+07 - - - 3.4332 0.9999 221125_WJC_METTL3_EV_vs_WT_F02.19100.19100.3 0.00457 Dec-44 R.QNLAEAITLAER.K sp|Q8TBA6|GOGA5_HUMAN 1 1327.7096 1.64 18291 19100 3 1327.710516 443.5771 Golgin subfamily A member 5 OS=Homo sapiens OX=9606 GN=GOLGA5 PE=1 SV=3 4.53 3379.1 - 646309 - - - 0.7057 - 2.039 0.396 - 174.2 1 2 0 0.0009 12 0 0 0 4.88E+06 2.99E+06 - - - 4.9296 1 221125_WJC_METTL3_EV_vs_WT_F02.19101.19101.2 1.23E-10 13/26 K.TLIDDDNPPVSFVK[136.11].F sp|P61964|WDR5_HUMAN 1 1566.8021 1.91 18292 19101 2 1566.803083 784.4083 WD repeat-containing protein 5 OS=Homo sapiens OX=9606 GN=WDR5 PE=1 SV=1 3.93 3379.2 - 590270 - - - 0.6344 - 2.333 0.629 - 402.3 1 2 0 0.001 14 0 0 0 1.49E+07 7.81E+06 - - - 5.8124 1 221125_WJC_METTL3_EV_vs_WT_F02.19102.19102.3 2.00E-08 19/60 K.VPPAVIIPPAAPLSGR[166.11].R "sp|Q9H4A3|WNK1_HUMAN,tr|F5GWT4|F5GWT4_HUMAN,tr|A0A6Q8PFM0|A0A6Q8PFM0_HUMAN" 3 1563.9376 2.24 18293 19102 3 1563.936914 522.3198 Serine\threonine-protein kinase WNK1 OS=Homo sapiens OX=9606 GN=WNK1 PE=1 SV=2 9.72 3379.3 - 450492 - - - -0.4508 - 3.618 0.57 - 658.1 1 2 0 -0.0007 16 0 0 0 2.38E+07 1.06E+07 - - - 8.1942 0.828 221125_WJC_METTL3_EV_vs_WT_F02.19103.19103.3 3.86 13/48 R.VKTWTR[166.11]HVDIFEK.D "sp|Q9GZR1|SENP6_HUMAN,tr|H0Y8Y8|H0Y8Y8_HUMAN" 2 1667.9023 - 18294 19103 3 1667.903239 556.9747 Sentrin-specific protease 6 OS=Homo sapiens OX=9606 GN=SENP6 PE=1 SV=2 8.57 3379.4 - 431769 - - - 0.5654 - 1.926 0.056 - 134.1 1 2 2 0.0009 13 0 0 0 - - - - - 0.9412 0.9992 221125_WJC_METTL3_EV_vs_WT_F02.19106.19106.2 0.00464 14-Jul K.DIEDVFYK.Y "sp|Q07955|SRSF1_HUMAN,tr|J3QQV5|J3QQV5_HUMAN,tr|J3KTL2|J3KTL2_HUMAN,tr|J3KSW7|J3KSW7_HUMAN" 4 1027.4862 0.11 18296 19106 2 1027.486476 514.7504 Serine\arginine-rich splicing factor 1 OS=Homo sapiens OX=9606 GN=SRSF1 PE=1 SV=2 4.03 3379.8 - 4.81E+06 - - - 0.2423 - 1.413 0.338 - 116.7 1 2 0 0.0002 8 0 0 0 2.20E+07 1.98E+08 - - - 2.5801 0.9996 221125_WJC_METTL3_EV_vs_WT_F02.19108.19108.3 0.0153 Dec-52 K.LGGSAVISLEGKPL.- "sp|P23528|COF1_HUMAN,tr|G3V1A4|G3V1A4_HUMAN,tr|E9PK25|E9PK25_HUMAN" 3 1339.7711 1.3 18298 19108 3 1339.771081 447.5976 Cofilin-1 OS=Homo sapiens OX=9606 GN=CFL1 PE=1 SV=3 6 3380 - 3.51E+06 - - - -0.0269 - 2.055 0.323 - 148.3 1 2 0 0 14 0 0 0 3.41E+07 2.63E+07 - - - 4.0553 0.9942 221125_WJC_METTL3_EV_vs_WT_F02.19110.19110.2 0.000666 24-Sep K.MVVPGLDGAQIPR[166.11].D "sp|P49327|FAS_HUMAN,tr|A0A0U1RQF0|A0A0U1RQF0_HUMAN" 2 1361.7365 12.96 18300 19110 2 1361.74395 681.8755 Fatty acid synthase OS=Homo sapiens OX=9606 GN=FASN PE=1 SV=3 5.59 3380.1 - 2.06E+06 - - - 5.4886 - 1.933 0.444 - 243.8 1 2 0 0.0075 13 0 0 0 2.81E+08 2.17E+07 - - - 4.0096 0.9997 221125_WJC_METTL3_EV_vs_WT_F02.19111.19111.2 1.72E-06 16-Dec K.THILLFLPK[136.11].S "sp|P07237|PDIA1_HUMAN,tr|A0A7P0TA97|A0A7P0TA97_HUMAN,tr|A0A7P0T8C0|A0A7P0T8C0_HUMAN,tr|H7BZ94|H7BZ94_HUMAN,tr|A0A7P0TA71|A0A7P0TA71_HUMAN,tr|I3L4M2|I3L4M2_HUMAN,tr|A0A7P0T9D6|A0A7P0T9D6_HUMAN,tr|A0A7P0T9K9|A0A7P0T9K9_HUMAN,tr|H0Y3Z3|H0Y3Z3_HUMAN,tr|A0A7P0TA35|A0A7P0TA35_HUMAN,tr|I3L514|I3L514_HUMAN,tr|A0A7P0TB26|A0A7P0TB26_HUMAN,tr|A0A7P0T9U6|A0A7P0T9U6_HUMAN,tr|I3L3P5|I3L3P5_HUMAN,tr|A0A7P0T8X1|A0A7P0T8X1_HUMAN" 15 1088.6838 1.45 18301 19111 2 1088.683473 545.3492 Protein disulfide-isomerase OS=Homo sapiens OX=9606 GN=P4HB PE=1 SV=3 8.44 3380.1 - 1.88E+06 - - - -0.2563 - 2.377 0.292 - 663.7 1 2 0 -0.0003 9 0 0 0 3.70E+07 2.55E+07 - - - 3.7025 0.9999 221125_WJC_METTL3_EV_vs_WT_F02.19114.19114.2 0.000407 18/28 K.LGQGVLVQVSPSLVK[136.11].R sp|Q13868|EXOS2_HUMAN 1 1530.9225 0.99 18304 19114 2 1530.921212 766.4685 Exosome complex component RRP4 OS=Homo sapiens OX=9606 GN=EXOSC2 PE=1 SV=2 8.75 3380.5 - 1.17E+06 - - - -0.8276 - 3.177 0.488 - 1375.1 1 2 0 -0.0013 15 0 0 0 2.19E+07 2.21E+07 - - - 5.4869 0.9996 221125_WJC_METTL3_EV_vs_WT_F02.19115.19115.2 0.000319 17/30 R.ADLTGISPSPNLYLSK.L sp|Q96P63|SPB12_HUMAN 1 1674.8829 999 18305 19115 2 1674.887752 838.4487 Serpin B12 OS=Homo sapiens OX=9606 GN=SERPINB12 PE=1 SV=1 5.88 3380.6 - 1.10E+06 - - - 2.9256 - 3.165 0.455 - 986.3 1 2 0 0.0049 16 0 0 0 8.87E+07 0.00E+00 - - - 5.2327 1 221125_WJC_METTL3_EV_vs_WT_F02.19117.19117.2 1.53E-08 16/28 K.LGQGVLVQVSPSLVK.R sp|Q13868|EXOS2_HUMAN 1 1522.9083 0.99 18307 19117 2 1522.90836 762.4614 Exosome complex component RRP4 OS=Homo sapiens OX=9606 GN=EXOSC2 PE=1 SV=2 8.75 3380.9 - 997079 - - - 0.0532 - 2.984 0.541 - 1004.9 1 2 0 0.0001 15 0 0 0 2.19E+07 2.21E+07 - - - 5.7246 0.9956 221125_WJC_METTL3_EV_vs_WT_F02.19118.19118.2 0.0487 16-Aug R.DTVELQLLK[136.11].G sp|O95900|TRUB2_HUMAN 1 1065.6161 0.99 18308 19118 2 1065.614048 533.8153 Mitochondrial mRNA pseudouridine synthase TRUB2 OS=Homo sapiens OX=9606 GN=TRUB2 PE=1 SV=1 4.37 3381 - 889089 - - - -1.95 - 1.528 0.201 - 113.1 1 2 0 -0.0021 9 0 0 0 5.78E+06 5.83E+06 - - - 1.7515 0.9999 221125_WJC_METTL3_EV_vs_WT_F02.19123.19123.2 5.24E-07 Dec-32 R.ELLMNGTSSTAEAIGLK[136.11].G "sp|Q9NUL3|STAU2_HUMAN,tr|E5RJN7|E5RJN7_HUMAN,tr|E7EVJ4|E7EVJ4_HUMAN,tr|E7EPX0|E7EPX0_HUMAN,tr|H0YBY0|H0YBY0_HUMAN" 5 1741.9012 1.77 18313 19123 2 1741.903069 871.9579 Double-stranded RNA-binding protein Staufen homolog 2 OS=Homo sapiens OX=9606 GN=STAU2 PE=1 SV=2 4.53 3381.7 - 316136 - - - 1.1011 - 2.675 0.527 - 254.2 1 2 0 0.0019 17 0 0 0 2.67E+06 1.51E+06 - - - 5.3519 0.9996 221125_WJC_METTL3_EV_vs_WT_F02.19128.19128.2 0.0027 14-Jul K.EAFQLFDR[166.11].T "sp|P60660|MYL6_HUMAN,tr|F8W1R7|F8W1R7_HUMAN,tr|G3V1V0|G3V1V0_HUMAN,tr|B7Z6Z4|B7Z6Z4_HUMAN,tr|G8JLA2|G8JLA2_HUMAN,tr|G3V1Y7|G3V1Y7_HUMAN,tr|J3KND3|J3KND3_HUMAN" 7 1034.5061 1.27 18316 19128 2 1034.505413 518.2603 Myosin light polypeptide 6 OS=Homo sapiens OX=9606 GN=MYL6 PE=1 SV=2 4.37 3382.2 - 1.99E+07 - - - -0.6303 - 1.515 0.394 - 192 1 2 0 -0.0007 8 0 0 0 4.97E+08 3.92E+08 - - - 3.2038 0.9998 221125_WJC_METTL3_EV_vs_WT_F02.19129.19129.2 0.000292 14-Aug K.EAFQLFDR.T "sp|P60660|MYL6_HUMAN,tr|F8W1R7|F8W1R7_HUMAN,tr|G3V1V0|G3V1V0_HUMAN,tr|B7Z6Z4|B7Z6Z4_HUMAN,tr|G8JLA2|G8JLA2_HUMAN,tr|G3V1Y7|G3V1Y7_HUMAN,tr|J3KND3|J3KND3_HUMAN" 7 1024.4978 1.28 18317 19129 2 1024.497357 513.2562 Myosin light polypeptide 6 OS=Homo sapiens OX=9606 GN=MYL6 PE=1 SV=2 4.37 3382.3 - 2.26E+07 - - - -0.4275 - 1.646 0.443 - 251.5 1 2 0 -0.0004 8 0 0 0 4.97E+08 3.88E+08 - - - 3.8159 0.9995 221125_WJC_METTL3_EV_vs_WT_F02.19130.19130.2 0.0104 14-Aug R.LNVWDLSK[136.11].L "sp|Q09028|RBBP4_HUMAN,sp|Q16576|RBBP7_HUMAN,tr|H0YCT5|H0YCT5_HUMAN,tr|H0YDK2|H0YDK2_HUMAN,tr|Q5JP02|Q5JP02_HUMAN,tr|H0YEU5|H0YEU5_HUMAN,tr|Q5JNZ6|Q5JNZ6_HUMAN,tr|H0YF10|H0YF10_HUMAN,tr|E9PC52|E9PC52_HUMAN" 9 981.5375 1.55 18318 19130 2 981.537161 491.776 Histone-binding protein RBBP4 OS=Homo sapiens OX=9606 GN=RBBP4 PE=1 SV=3 5.84 3382.3 - 1.78E+07 - - - -0.327 - 1.889 0.293 - 240.1 1 2 0 -0.0003 8 0 0 0 2.90E+08 1.88E+08 - - - 3.1233 0.9997 221125_WJC_METTL3_EV_vs_WT_F02.19131.19131.2 0.000546 18-Oct K.FAAQELIEVK[136.11].R "sp|Q86U44|MTA70_HUMAN,tr|F5H6D8|F5H6D8_HUMAN,tr|H0YFV6|H0YFV6_HUMAN,tr|B4DTN4|B4DTN4_HUMAN" 4 1154.6427 0.01 18319 19131 2 1154.641485 578.3286 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 4.53 3382.4 - 6.83E+06 - - - -1.0306 - 1.88 0.41 - 267.1 1 2 0 -0.0012 10 0 0 0 4.97E+05 7.40E+07 - - - 3.831 0.9995 221125_WJC_METTL3_EV_vs_WT_F02.19132.19132.2 0.0044 18-Aug R.EGDLLFTVAK.D "sp|Q13347|EIF3I_HUMAN,tr|A0A7I2V613|A0A7I2V613_HUMAN,tr|A0A7I2V3N2|A0A7I2V3N2_HUMAN,tr|A0A7I2YQU2|A0A7I2YQU2_HUMAN,tr|A0A7I2YQX4|A0A7I2YQX4_HUMAN,tr|A0A7I2YQI6|A0A7I2YQI6_HUMAN,tr|A0A7I2YQF8|A0A7I2YQF8_HUMAN,tr|Q5TFK1|Q5TFK1_HUMAN,tr|A0A7I2V3U3|A0A7I2V3U3_HUMAN,tr|A0A7I2V607|A0A7I2V607_HUMAN,tr|A0A7I2V640|A0A7I2V640_HUMAN,tr|A0A7P0MRT9|A0A7P0MRT9_HUMAN,tr|A0A7I2V3T4|A0A7I2V3T4_HUMAN,tr|A0A7I2V3K6|A0A7I2V3K6_HUMAN,tr|A0A7I2V4S8|A0A7I2V4S8_HUMAN,tr|A0A7I2V5V8|A0A7I2V5V8_HUMAN,tr|A0A7I2V391|A0A7I2V391_HUMAN,tr|A0A7I2V5E4|A0A7I2V5E4_HUMAN,tr|A0A7I2YQN1|A0A7I2YQN1_HUMAN,tr|A0A7I2V2M3|A0A7I2V2M3_HUMAN,tr|A0A7I2V4C2|A0A7I2V4C2_HUMAN,tr|A0A7I2YQP9|A0A7I2YQP9_HUMAN,tr|A0A7I2YQI2|A0A7I2YQI2_HUMAN,tr|A0A7I2V685|A0A7I2V685_HUMAN" 24 1091.5863 0.71 18320 19132 2 1091.586228 546.8004 Eukaryotic translation initiation factor 3 subunit I OS=Homo sapiens OX=9606 GN=EIF3I PE=1 SV=1 4.37 3382.4 - 5.07E+06 - - - -0.044 - 1.841 0.295 - 209.5 1 2 0 0 10 0 0 0 5.65E+07 7.95E+07 - - - 2.9234 0.9939 221125_WJC_METTL3_EV_vs_WT_F02.19133.19133.2 0.759 16-Jul R.LQQFLEFKE.- sp|Q9BTX1|NDC1_HUMAN 1 1180.6128 7.4 18321 19133 2 1180.613228 591.3137 Nucleoporin NDC1 OS=Homo sapiens OX=9606 GN=NDC1 PE=1 SV=2 4.86 3382.4 - 3.19E+06 - - - 0.3413 - 1.291 0.165 - 114.2 1 2 0 0.0004 9 0 0 0 5.19E+07 7.02E+06 - - - 0.9985 0.9998 221125_WJC_METTL3_EV_vs_WT_F02.19134.19134.3 0.0138 13/52 K.LGGSAVISLEGK[136.11]PL.- "sp|P23528|COF1_HUMAN,tr|G3V1A4|G3V1A4_HUMAN,tr|E9PK25|E9PK25_HUMAN" 3 1347.7853 1.31 18322 19134 3 1347.783669 450.269 Cofilin-1 OS=Homo sapiens OX=9606 GN=CFL1 PE=1 SV=3 6 3382.5 - 3.11E+06 - - - -1.2227 - 1.992 0.382 - 158.4 1 2 0 -0.0016 14 0 0 0 3.41E+07 2.61E+07 - - - 4.6299 0.9998 221125_WJC_METTL3_EV_vs_WT_F02.19135.19135.2 0.000418 18-Nov R.QIDQFLVVAR.A "sp|Q9BTC8|MTA3_HUMAN,sp|O94776|MTA2_HUMAN,sp|Q13330|MTA1_HUMAN,tr|E9PCS8|E9PCS8_HUMAN,tr|H0Y4T7|H0Y4T7_HUMAN,tr|E7EQY4|E7EQY4_HUMAN,tr|E7EV10|E7EV10_HUMAN,tr|F6RRE2|F6RRE2_HUMAN,tr|E7ESY4|E7ESY4_HUMAN" 9 1187.6663 1.02 18323 19135 2 1187.668547 594.8404 Metastasis-associated protein MTA3 OS=Homo sapiens OX=9606 GN=MTA3 PE=1 SV=2 5.84 3382.6 - 2.42E+06 - - - 1.9273 - 2.409 0.509 - 731.8 1 2 0 0.0023 10 0 0 0 7.99E+07 7.86E+07 - - - 5.2539 0.9999 221125_WJC_METTL3_EV_vs_WT_F02.19138.19138.2 0.000633 18-Sep K.GFAYIEFSDK.E "sp|Q86U42|PABP2_HUMAN,tr|B4DEH8|B4DEH8_HUMAN,tr|G3V4T2|G3V4T2_HUMAN,tr|H0YJH9|H0YJH9_HUMAN,tr|A0A7I2V383|A0A7I2V383_HUMAN" 5 1175.5499 1.13 18326 19138 2 1175.548918 588.7822 Polyadenylate-binding protein 2 OS=Homo sapiens OX=9606 GN=PABPN1 PE=1 SV=3 4.37 3382.9 - 1.29E+06 - - - -0.8268 - 2.024 0.505 - 283.1 1 2 0 -0.001 10 0 0 0 4.86E+07 4.31E+07 - - - 4.7387 0.9101 221125_WJC_METTL3_EV_vs_WT_F02.19139.19139.2 0.0147 14-Sep Y.LDVSILGK[136.11].F sp|Q86U44|MTA70_HUMAN 1 851.5208 0.001 18327 19139 2 851.520571 426.7677 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 5.84 3383 - 1.24E+06 - - - -0.2325 - 1.944 0.122 - 224.6 1 1 0 -0.0002 8 0 0 0 0.00E+00 8.70E+06 - - - 1.9469 0.9993 221125_WJC_METTL3_EV_vs_WT_F02.19140.19140.3 0.00602 14/36 K.TILFIDEIHR[166.11].F sp|Q96S55|WRIP1_HUMAN 1 1265.7007 0.65 18328 19140 3 1265.69905 422.9075 ATPase WRNIP1 OS=Homo sapiens OX=9606 GN=WRNIP1 PE=1 SV=2 5.29 3383.1 - 1.22E+06 - - - -1.3368 - 2.373 0.235 - 250.8 1 2 0 -0.0017 10 0 0 0 5.10E+06 7.79E+06 - - - 3.6833 0.9999 221125_WJC_METTL3_EV_vs_WT_F02.19141.19141.2 2.15E-09 13/26 R.FGIQAQMVTTDFQK[136.11].L "sp|P49720|PSB3_HUMAN,tr|A0A087WXQ8|A0A087WXQ8_HUMAN,tr|A0A087WUL2|A0A087WUL2_HUMAN,tr|A0A087WY10|A0A087WY10_HUMAN" 4 1620.8061 0.52 18329 19141 2 1620.805465 811.4103 Proteasome subunit beta type-3 OS=Homo sapiens OX=9606 GN=PSMB3 PE=1 SV=2 5.84 3383.3 - 1.04E+06 - - - -0.4091 - 2.89 0.519 - 665.4 1 2 0 -0.0007 14 0 0 0 6.04E+06 1.15E+07 - - - 5.5373 1 221125_WJC_METTL3_EV_vs_WT_F02.19142.19142.2 4.99E-08 18/34 K.VLAGETLSVNDPPDVLDR.Q "sp|Q12906|ILF3_HUMAN,tr|K7EQR9|K7EQR9_HUMAN,tr|K7EKJ9|K7EKJ9_HUMAN" 3 1908.9793 1.37 18330 19142 2 1908.981607 955.4969 Interleukin enhancer-binding factor 3 OS=Homo sapiens OX=9606 GN=ILF3 PE=1 SV=3 3.84 3383.4 - 959939 - - - 1.2232 - 3.564 0.615 - 486.3 1 2 0 0.0023 18 0 0 0 1.01E+08 7.37E+07 - - - 6.7072 1 221125_WJC_METTL3_EV_vs_WT_F02.19143.19143.2 9.60E-09 16/28 C.FANFESDEVELSYAK[136.11].N "sp|Q00839|HNRPU_HUMAN,tr|A0A1W2PQL0|A0A1W2PQL0_HUMAN,tr|A0A1W2PPL4|A0A1W2PPL4_HUMAN,tr|A0A1W2PQ74|A0A1W2PQ74_HUMAN,tr|Q5RI18|Q5RI18_HUMAN,tr|A0A1W2PP35|A0A1W2PP35_HUMAN,tr|A0A1W2PPS1|A0A1W2PPS1_HUMAN,tr|A0A1W2PRZ7|A0A1W2PRZ7_HUMAN,tr|A0A1W2PPH7|A0A1W2PPH7_HUMAN,tr|A0A1W2PP34|A0A1W2PP34_HUMAN,tr|A0A1X7SBS1|A0A1X7SBS1_HUMAN" 11 1755.8083 0.96 18331 19143 2 1755.802384 878.9114 Heterogeneous nuclear ribonucleoprotein U OS=Homo sapiens OX=9606 GN=HNRNPU PE=1 SV=6 4 3383.5 - 816406 - - - -3.3677 - 3.433 0.691 - 1051.3 1 1 0 -0.0059 15 0 0 0 3.57E+07 3.73E+07 - - - 7.1753 1 221125_WJC_METTL3_EV_vs_WT_F02.19144.19144.2 1.48E-08 15/28 C.FANFESDEVELSYAK.N "sp|Q00839|HNRPU_HUMAN,tr|A0A1W2PQL0|A0A1W2PQL0_HUMAN,tr|A0A1W2PPL4|A0A1W2PPL4_HUMAN,tr|A0A1W2PQ74|A0A1W2PQ74_HUMAN,tr|Q5RI18|Q5RI18_HUMAN,tr|A0A1W2PP35|A0A1W2PP35_HUMAN,tr|A0A1W2PPS1|A0A1W2PPS1_HUMAN,tr|A0A1W2PRZ7|A0A1W2PRZ7_HUMAN,tr|A0A1W2PPH7|A0A1W2PPH7_HUMAN,tr|A0A1W2PP34|A0A1W2PP34_HUMAN,tr|A0A1X7SBS1|A0A1X7SBS1_HUMAN" 11 1747.7941 0.96 18332 19144 2 1747.795965 874.9043 Heterogeneous nuclear ribonucleoprotein U OS=Homo sapiens OX=9606 GN=HNRNPU PE=1 SV=6 4 3383.7 - 694780 - - - 1.0688 - 3.199 0.668 - 966.2 1 1 0 0.0019 15 0 0 0 3.57E+07 3.71E+07 - - - 6.8332 0.9989 221125_WJC_METTL3_EV_vs_WT_F02.19145.19145.3 0.00223 Nov-36 K.TILFIDEIHR.F sp|Q96S55|WRIP1_HUMAN 1 1255.6925 0.65 18333 19145 3 1255.689723 419.5714 ATPase WRNIP1 OS=Homo sapiens OX=9606 GN=WRNIP1 PE=1 SV=2 5.29 3383.8 - 662972 - - - -2.1892 - 1.963 0.293 - 144 1 2 0 -0.0027 10 0 0 0 5.02E+06 7.70E+06 - - - 3.7757 1 221125_WJC_METTL3_EV_vs_WT_F02.19146.19146.2 2.11E-10 15/26 R.FGIQAQMVTTDFQK.L "sp|P49720|PSB3_HUMAN,tr|A0A087WXQ8|A0A087WXQ8_HUMAN,tr|A0A087WUL2|A0A087WUL2_HUMAN,tr|A0A087WY10|A0A087WY10_HUMAN" 4 1612.7919 0.53 18334 19146 2 1612.78567 807.4032 Proteasome subunit beta type-3 OS=Homo sapiens OX=9606 GN=PSMB3 PE=1 SV=2 5.84 3383.9 - 629166 - - - -3.8802 - 3.214 0.628 - 1192.7 1 2 0 -0.0063 14 0 0 0 6.04E+06 1.13E+07 - - - 6.6073 0.9999 221125_WJC_METTL3_EV_vs_WT_F02.19152.19152.2 7.85E-07 13/20 R.MGPGIGAILER[166.11].S "sp|Q9P2K5|MYEF2_HUMAN,tr|A0A0A0MR39|A0A0A0MR39_HUMAN,tr|A0A0C4DGV1|A0A0C4DGV1_HUMAN,tr|A0A087WUT0|A0A087WUT0_HUMAN,tr|H0YKS1|H0YKS1_HUMAN,tr|H0YN19|H0YN19_HUMAN,tr|A0A0A0MQW0|A0A0A0MQW0_HUMAN" 7 1122.6095 1.07 18338 19152 2 1122.609384 562.312 Myelin expression factor 2 OS=Homo sapiens OX=9606 GN=MYEF2 PE=1 SV=3 5.75 3384.5 - 3.10E+06 - - - -0.0891 - 2.366 0.468 - 600.3 1 2 0 -0.0001 11 0 0 0 5.80E+07 5.40E+07 - - - 4.8274 1 221125_WJC_METTL3_EV_vs_WT_F02.19153.19153.2 5.45E-12 22/34 K.VLAGETLSVNDPPDVLDR[166.11].Q "sp|Q12906|ILF3_HUMAN,tr|K7EQR9|K7EQR9_HUMAN,tr|K7EKJ9|K7EKJ9_HUMAN" 3 1918.9875 1.4 18339 19153 2 1918.986156 960.501 Interleukin enhancer-binding factor 3 OS=Homo sapiens OX=9606 GN=ILF3 PE=1 SV=3 3.84 3384.6 - 2.55E+06 - - - -0.7223 - 3.905 0.658 - 815.6 1 2 0 -0.0014 18 0 0 0 1.03E+08 7.37E+07 - - - 7.2497 0.9997 221125_WJC_METTL3_EV_vs_WT_F02.19159.19159.2 0.00325 22-Oct R.FLEYSISDEITK[136.11].A sp|Q9BTE3|MCMBP_HUMAN 1 1451.7275 2.18 18345 19159 2 1451.725352 726.871 Mini-chromosome maintenance complex-binding protein OS=Homo sapiens OX=9606 GN=MCMBP PE=1 SV=2 4.14 3385.3 - 680104 - - - -1.4982 - 2.008 0.471 - 257.6 1 2 0 -0.0022 12 0 0 0 6.78E+06 3.11E+06 - - - 4.3534 0.9934 221125_WJC_METTL3_EV_vs_WT_F02.19161.19161.3 0.502 Sep-40 R.NPIHAIGLLIR[166.11].E "sp|Q12769|NU160_HUMAN,tr|E9PR16|E9PR16_HUMAN,tr|G3V198|G3V198_HUMAN" 3 1225.7534 1.97 18347 19161 3 1225.753153 409.5918 Nuclear pore complex protein Nup160 OS=Homo sapiens OX=9606 GN=NUP160 PE=1 SV=3 9.76 3385.5 - 571500 - - - -0.2399 - 1.83 0.162 - 69 1 2 0 -0.0003 11 0 0 0 9.73E+06 4.93E+06 - - - 2.0628 0.9991 221125_WJC_METTL3_EV_vs_WT_F02.19162.19162.2 0.00252 16-Sep K.DQVLAMLEK[136.11].A sp|Q14008|CKAP5_HUMAN 1 1053.562 1.11 18348 19162 2 1053.564202 527.7883 Cytoskeleton-associated protein 5 OS=Homo sapiens OX=9606 GN=CKAP5 PE=1 SV=3 4.37 3385.7 - 498420 - - - 2.1071 - 1.933 0.322 - 291.1 1 2 0 0.0022 9 0 0 0 1.57E+07 1.41E+07 - - - 3.3253 0.9999 221125_WJC_METTL3_EV_vs_WT_F02.19165.19165.2 9.57E-05 22-Dec R.LNVGGTYFLTTR.Q "sp|Q9NXV2|KCTD5_HUMAN,tr|H3BSS5|H3BSS5_HUMAN" 2 1340.7089 3.81 18349 19165 2 1340.708864 671.3617 BTB\POZ domain-containing protein KCTD5 OS=Homo sapiens OX=9606 GN=KCTD5 PE=1 SV=1 8.75 3386.1 - 1.22E+08 - - - 0.0097 - 2.553 0.483 - 420.3 1 2 0 0 12 0 0 0 4.58E+09 1.20E+09 - - - 5.0745 0.9996 221125_WJC_METTL3_EV_vs_WT_F02.19168.19168.2 4.74E-05 20-Oct K.EGMNIVEAMER[166.11].F sp|P62937|PPIA_HUMAN 1 1287.5827 0.84 18352 19168 2 1287.582135 644.7986 Peptidyl-prolyl cis-trans isomerase A OS=Homo sapiens OX=9606 GN=PPIA PE=1 SV=2 4.25 3386.2 - 2.00E+06 - - - -0.4209 - 2.008 0.304 - 390.6 1 2 0 -0.0005 11 0 0 0 7.36E+07 8.78E+07 - - - 3.1721 0.9999 221125_WJC_METTL3_EV_vs_WT_F02.19170.19170.2 0.000579 15/28 R.LLEAQIATGGIIDPK[136.11].E sp|P15924|DESP_HUMAN 1 1545.8858 23.37 18354 19170 2 1545.884569 773.9502 Desmoplakin OS=Homo sapiens OX=9606 GN=DSP PE=1 SV=3 4.37 3386.5 - 916525 - - - -0.7698 - 2.934 0.466 - 570.5 1 2 0 -0.0012 15 0 0 0 2.85E+08 1.22E+07 - - - 5.1288 0.9984 221125_WJC_METTL3_EV_vs_WT_F02.19173.19173.2 0.0279 18-Sep K.AYLPQELLGK[136.11].E "sp|P51398|RT29_HUMAN,tr|V9GYA7|V9GYA7_HUMAN,tr|V9GZ03|V9GZ03_HUMAN,tr|V9GZ61|V9GZ61_HUMAN,tr|V9GYC9|V9GYC9_HUMAN" 5 1138.6478 1.43 18357 19173 2 1138.646482 570.3312 "28S ribosomal protein S29, mitochondrial OS=Homo sapiens OX=9606 GN=DAP3 PE=1 SV=1" 6.05 3386.9 - 540710 - - - -1.1224 - 1.425 0.291 - 214.8 1 2 0 -0.0013 10 0 0 0 1.36E+07 9.50E+06 - - - 2.1785 0.9999 221125_WJC_METTL3_EV_vs_WT_F02.19177.19177.2 1.00E-07 20-Nov K.DFMIQGGDFTR[166.11].G "sp|P23284|PPIB_HUMAN,tr|A0A7P0Z497|A0A7P0Z497_HUMAN,tr|A0A7P0T7U3|A0A7P0T7U3_HUMAN,tr|A0A7P0TB45|A0A7P0TB45_HUMAN" 4 1295.5844 1.05 18359 19177 2 1295.585614 648.7995 Peptidyl-prolyl cis-trans isomerase B OS=Homo sapiens OX=9606 GN=PPIB PE=1 SV=2 4.21 3387.4 - 4.55E+06 - - - 0.9432 - 2.211 0.57 - 476 1 2 0 0.0012 11 0 0 0 8.20E+07 7.78E+07 - - - 5.3971 0.9997 221125_WJC_METTL3_EV_vs_WT_F02.19179.19179.2 5.03E-05 22-Dec K.LLNQPNQWPLVK.A sp|P14923|PLAK_HUMAN 1 1448.814 200.75 18361 19179 2 1448.8158 725.4143 Junction plakoglobin OS=Homo sapiens OX=9606 GN=JUP PE=1 SV=3 8.75 3387.6 - 1.64E+06 - - - 1.2534 - 2.044 0.424 - 486.6 1 2 0 0.0018 12 0 0 0 5.63E+07 2.80E+05 - - - 4.0531 0.9999 221125_WJC_METTL3_EV_vs_WT_F02.19180.19180.2 9.09E-07 16/30 K.VPPAVIIPPAAPLSGR.R "sp|Q9H4A3|WNK1_HUMAN,tr|F5GWT4|F5GWT4_HUMAN,tr|A0A6Q8PFM0|A0A6Q8PFM0_HUMAN" 3 1553.9293 2.32 18362 19180 2 1553.929634 777.972 Serine\threonine-protein kinase WNK1 OS=Homo sapiens OX=9606 GN=WNK1 PE=1 SV=2 9.72 3387.7 - 1.45E+06 - - - 0.1834 - 2.796 0.404 - 619.1 1 2 0 0.0003 16 0 0 0 4.19E+07 1.81E+07 - - - 4.5527 0.9999 221125_WJC_METTL3_EV_vs_WT_F02.19181.19181.2 2.01E-06 14/24 R.WQEVIPYTPAMQR.Y "sp|P09601|HMOX1_HUMAN,tr|B1AHA8|B1AHA8_HUMAN,tr|A0A7I2V3I1|A0A7I2V3I1_HUMAN" 3 1617.7973 1.8 18363 19181 2 1617.797373 809.906 Heme oxygenase 1 OS=Homo sapiens OX=9606 GN=HMOX1 PE=1 SV=1 6 3387.8 - 1.42E+06 - - - 0.0155 - 2.453 0.567 - 482.4 1 2 0 0 13 0 0 0 2.08E+07 1.16E+07 - - - 5.5318 0.9999 221125_WJC_METTL3_EV_vs_WT_F02.19190.19190.3 0.000225 Oct-44 R.LNVGGTYFLTTR.Q "sp|Q9NXV2|KCTD5_HUMAN,tr|H3BSS5|H3BSS5_HUMAN" 2 1340.7089 2.73 18371 19190 3 1340.70817 447.9102 BTB\POZ domain-containing protein KCTD5 OS=Homo sapiens OX=9606 GN=KCTD5 PE=1 SV=1 8.75 3388.7 - 6.69E+06 - - - -0.5079 - 1.87 0.442 - 125.8 1 2 0 -0.0007 12 0 0 0 6.32E+07 2.32E+07 - - - 5.2027 1 221125_WJC_METTL3_EV_vs_WT_F02.19192.19192.2 0.00176 13/24 K.IIDETMAQLQDLK.N "sp|Q14683|SMC1A_HUMAN,tr|G8JLG1|G8JLG1_HUMAN,tr|A0A6Q8PHC3|A0A6Q8PHC3_HUMAN" 3 1516.7807 0.74 18373 19192 2 1516.779066 759.3976 Structural maintenance of chromosomes protein 1A OS=Homo sapiens OX=9606 GN=SMC1A PE=1 SV=2 4.03 3388.8 - 3.85E+06 - - - -1.074 - 2.761 0.565 - 518.8 1 2 0 -0.0016 13 0 0 0 3.69E+07 4.98E+07 - - - 5.8201 0.9998 221125_WJC_METTL3_EV_vs_WT_F02.19193.19193.2 0.000308 18-Nov K.WTETEIEMLR.A "sp|Q8IXM2|BAP18_HUMAN,tr|H0YIS7|H0YIS7_HUMAN,tr|F8W038|F8W038_HUMAN,tr|F8W1H0|F8W1H0_HUMAN" 4 1306.6227 1.39 18374 19193 2 1306.624307 654.3186 Chromatin complexes subunit BAP18 OS=Homo sapiens OX=9606 GN=BAP18 PE=1 SV=1 4.25 3388.8 - 2.28E+06 - - - 1.2008 - 2.218 0.442 - 527.9 1 2 0 0.0016 10 0 0 0 2.43E+07 1.75E+07 - - - 4.5287 0.9998 221125_WJC_METTL3_EV_vs_WT_F02.19200.19200.2 0.0212 18-Sep K.IYVISLAEPR.L "sp|P14868|SYDC_HUMAN,tr|C9JQM9|C9JQM9_HUMAN,tr|C9J7S3|C9J7S3_HUMAN,tr|C9JLC1|C9JLC1_HUMAN" 4 1159.6601 1.32 18381 19200 2 1159.660424 580.8373 "Aspartate--tRNA ligase, cytoplasmic OS=Homo sapiens OX=9606 GN=DARS1 PE=1 SV=2" 6 3389.6 - 654194 - - - 0.2708 - 1.984 0.395 - 209 1 2 0 0.0003 10 0 0 0 9.60E+06 7.28E+06 - - - 3.8707 0.9999 221125_WJC_METTL3_EV_vs_WT_F02.19202.19202.2 3.08E-07 30-Oct K.LLELTSSYSPDVSDYK[136.11].E sp|P38432|COIL_HUMAN 1 1823.892 0.46 18383 19202 2 1823.893712 912.9533 Coilin OS=Homo sapiens OX=9606 GN=COIL PE=1 SV=1 4.03 3389.9 - 495706 - - - 0.9244 - 2.269 0.584 - 280.9 1 2 0 0.0017 16 0 0 0 1.22E+06 2.64E+06 - - - 5.3683 0.9994 221125_WJC_METTL3_EV_vs_WT_F02.19205.19205.2 2.37E-05 18-Aug R.NLVC[160.03]TDLFTR[166.11].G sp|P26196|DDX6_HUMAN 1 1247.6208 0.71 18385 19205 2 1247.622054 624.8177 Probable ATP-dependent RNA helicase DDX6 OS=Homo sapiens OX=9606 GN=DDX6 PE=1 SV=2 5.83 3390.2 - 7.92E+06 - - - 1.0227 - 1.741 0.336 - 205.1 1 2 0 0.0013 10 0 0 0 1.57E+08 2.21E+08 - - - 3.07 0.9998 221125_WJC_METTL3_EV_vs_WT_F02.19207.19207.2 0.00584 20-Oct R.TIGIIGAPFSK.G "sp|P05089|ARGI1_HUMAN,tr|A0A5F9ZH78|A0A5F9ZH78_HUMAN" 2 1102.6386 7.71 18386 19207 2 1102.637992 552.3266 Arginase-1 OS=Homo sapiens OX=9606 GN=ARG1 PE=1 SV=2 8.41 3390.4 - 7.37E+06 - - - -0.5931 - 1.953 0.412 - 254.7 1 2 0 -0.0007 11 0 0 0 2.05E+08 2.66E+07 - - - 3.8946 0.9996 221125_WJC_METTL3_EV_vs_WT_F02.19209.19209.2 0.00272 16-Sep K.ALQFLEEVK.V sp|P40227|TCPZ_HUMAN 1 1075.5914 0.45 18388 19209 2 1075.591347 538.803 T-complex protein 1 subunit zeta OS=Homo sapiens OX=9606 GN=CCT6A PE=1 SV=3 4.53 3390.5 - 3.09E+06 - - - -0.013 - 1.883 0.319 - 276.4 1 2 0 0 9 0 0 0 9.70E+08 2.13E+09 - - - 3.228 0.9988 221125_WJC_METTL3_EV_vs_WT_F02.19210.19210.2 0.00268 18-Nov R.QIDQFLVVAR[166.11].A "sp|Q9BTC8|MTA3_HUMAN,sp|O94776|MTA2_HUMAN,sp|Q13330|MTA1_HUMAN,tr|E9PCS8|E9PCS8_HUMAN,tr|H0Y4T7|H0Y4T7_HUMAN,tr|E7EQY4|E7EQY4_HUMAN,tr|E7EV10|E7EV10_HUMAN,tr|F6RRE2|F6RRE2_HUMAN,tr|E7ESY4|E7ESY4_HUMAN" 9 1197.6745 1.01 18389 19210 2 1197.671546 599.8445 Metastasis-associated protein MTA3 OS=Homo sapiens OX=9606 GN=MTA3 PE=1 SV=2 5.84 3390.6 - 2.51E+06 - - - -2.4898 - 1.61 0.4 - 473.3 1 2 0 -0.003 10 0 0 0 7.97E+07 7.86E+07 - - - 3.3238 0.9941 221125_WJC_METTL3_EV_vs_WT_F02.19211.19211.2 0.484 14-Jul R.DFSLEQLR.Q sp|O15173|PGRC2_HUMAN 1 1006.5084 1.35 18390 19211 2 1006.509947 504.2615 Membrane-associated progesterone receptor component 2 OS=Homo sapiens OX=9606 GN=PGRMC2 PE=1 SV=1 4.37 3390.6 - 2.29E+06 - - - 1.5767 - 1.535 0.146 - 171.6 1 2 0 0.0016 8 0 0 0 7.75E+07 5.75E+07 - - - 1.4113 0.999 221125_WJC_METTL3_EV_vs_WT_F02.19212.19212.2 0.0863 18-Oct K.LSLEGIVVQR[166.11].A sp|P13984|T2FB_HUMAN 1 1122.6636 1.22 18391 19212 2 1122.664676 562.3391 General transcription factor IIF subunit 2 OS=Homo sapiens OX=9606 GN=GTF2F2 PE=1 SV=2 6 3390.7 - 1.62E+06 - - - 0.9326 - 1.947 0.226 - 262.6 1 2 0 0.001 10 0 0 0 2.76E+07 2.25E+07 - - - 2.5697 0.9959 221125_WJC_METTL3_EV_vs_WT_F02.19215.19215.2 0.00173 16-Sep R.EIDSWFSER.R "sp|Q9H4I2|ZHX3_HUMAN,sp|Q9Y6X8|ZHX2_HUMAN,tr|H0Y6F5|H0Y6F5_HUMAN" 3 1167.5197 2.07 18394 19215 2 1167.524104 584.7671 Zinc fingers and homeoboxes protein 3 OS=Homo sapiens OX=9606 GN=ZHX3 PE=1 SV=3 4.14 3391 - 670392 - - - 3.8124 - 1.747 0.321 - 240.8 1 2 0 0.0045 9 0 0 0 6.43E+06 3.11E+06 - - - 3.0245 1 221125_WJC_METTL3_EV_vs_WT_F02.19217.19217.3 6.40E-06 14/72 R.MDSFDEDLARPSGLLAQER.K "sp|Q9Y2W1|TR150_HUMAN,tr|A0A3B3ITZ9|A0A3B3ITZ9_HUMAN" 2 2149.011 6.3 18396 19217 3 2149.010501 717.3443 Thyroid hormone receptor-associated protein 3 OS=Homo sapiens OX=9606 GN=THRAP3 PE=1 SV=2 4.1 3391.3 - 508163 - - - -0.2243 - 2.585 0.54 - 239.5 1 2 0 -0.0005 19 0 0 0 3.61E+06 5.73E+05 - - - 6.8936 1 221125_WJC_METTL3_EV_vs_WT_F02.19220.19220.2 0.000327 16/28 R.LLEAQIATGGIIDPK.E sp|P15924|DESP_HUMAN 1 1537.8716 23.59 18398 19220 2 1537.870754 769.9431 Desmoplakin OS=Homo sapiens OX=9606 GN=DSP PE=1 SV=3 4.37 3391.6 - 1.54E+07 - - - -0.5235 - 3.458 0.541 - 758.2 1 2 0 -0.0008 15 0 0 0 2.88E+08 1.22E+07 - - - 6.0869 0.9949 221125_WJC_METTL3_EV_vs_WT_F02.19224.19224.2 9.43E-08 28-Oct K.ILGSGISSSSVLHGM.V sp|P50990|TCPQ_HUMAN 1 1443.7392 - 18401 19224 2 1443.739435 722.8769 T-complex protein 1 subunit theta OS=Homo sapiens OX=9606 GN=CCT8 PE=1 SV=4 6.74 3392 - 2.89E+06 - - - 0.187 - 2.241 0.628 - 213.1 1 1 0 0.0003 15 0 0 0 - - - - - 5.6632 1 221125_WJC_METTL3_EV_vs_WT_F02.19225.19225.2 1.25E-06 13/22 R.LLLENYEEYAAR[166.11].A "sp|Q16763|UBE2S_HUMAN,tr|K7EPJ1|K7EPJ1_HUMAN" 2 1492.7437 0.64 18402 19225 2 1492.742924 747.3791 Ubiquitin-conjugating enzyme E2 S OS=Homo sapiens OX=9606 GN=UBE2S PE=1 SV=2 4.25 3392.1 - 2.67E+06 - - - -0.5393 - 2.8 0.594 - 659.1 1 2 0 -0.0008 12 0 0 0 1.77E+07 2.78E+07 - - - 6.1371 0.9987 221125_WJC_METTL3_EV_vs_WT_F02.19226.19226.2 1.82E-05 20-Dec R.VFISNIPYDMK[136.11].W "sp|Q9P2K5|MYEF2_HUMAN,tr|A0A0A0MR39|A0A0A0MR39_HUMAN,tr|A0A087WUT0|A0A087WUT0_HUMAN,tr|A0A087WWC8|A0A087WWC8_HUMAN,tr|A0A0A0MQW0|A0A0A0MQW0_HUMAN" 5 1333.6832 1.18 18403 19226 2 1333.677339 667.8489 Myelin expression factor 2 OS=Homo sapiens OX=9606 GN=MYEF2 PE=1 SV=3 5.81 3392.3 - 1.85E+06 - - - -4.3646 - 2.07 0.557 - 477 1 2 0 -0.0058 11 0 0 0 1.79E+08 1.52E+08 - - - 5.1214 0.9962 221125_WJC_METTL3_EV_vs_WT_F02.19227.19227.2 0.334 16-Jul K.LQYEGIFIK.D sp|Q15459|SF3A1_HUMAN 1 1109.6121 0.92 18404 19227 2 1109.612522 555.8133 Splicing factor 3A subunit 1 OS=Homo sapiens OX=9606 GN=SF3A1 PE=1 SV=1 6 3392.3 - 1.57E+06 - - - 0.383 - 1.434 0.17 - 110.9 1 2 0 0.0004 9 0 0 0 2.29E+07 2.49E+07 - - - 1.3393 0.9767 221125_WJC_METTL3_EV_vs_WT_F02.19228.19228.2 0.0226 16-Aug K.LQYEGIFIK[136.11].D sp|Q15459|SF3A1_HUMAN 1 1117.6263 0.96 18405 19228 2 1117.621627 559.8204 Splicing factor 3A subunit 1 OS=Homo sapiens OX=9606 GN=SF3A1 PE=1 SV=1 6 3392.4 - 1.36E+06 - - - -4.1785 - 1.586 0.18 - 153.6 1 2 0 -0.0047 9 0 0 0 2.28E+07 2.37E+07 - - - 1.7033 0.997 221125_WJC_METTL3_EV_vs_WT_F02.19231.19231.2 1.15E-07 22-Dec R.LLLENYEEYAAR.A "sp|Q16763|UBE2S_HUMAN,tr|K7EPJ1|K7EPJ1_HUMAN" 2 1482.7355 0.86 18407 19231 2 1482.726695 742.375 Ubiquitin-conjugating enzyme E2 S OS=Homo sapiens OX=9606 GN=UBE2S PE=1 SV=2 4.25 3392.8 - 1.10E+06 - - - -5.9107 - 2.581 0.558 - 529.8 1 2 0 -0.0088 12 0 0 0 2.39E+07 2.78E+07 - - - 5.6545 0.9991 221125_WJC_METTL3_EV_vs_WT_F02.19233.19233.2 0.0213 20-Oct R.VFISNIPYDMK.W "sp|Q9P2K5|MYEF2_HUMAN,tr|A0A0A0MR39|A0A0A0MR39_HUMAN,tr|A0A087WUT0|A0A087WUT0_HUMAN,tr|A0A087WWC8|A0A087WWC8_HUMAN,tr|A0A0A0MQW0|A0A0A0MQW0_HUMAN" 5 1325.669 1.02 18408 19233 2 1325.666457 663.8418 Myelin expression factor 2 OS=Homo sapiens OX=9606 GN=MYEF2 PE=1 SV=3 5.81 3393 - 2.41E+06 - - - -1.8881 - 1.756 0.35 - 319.5 1 2 0 -0.0025 11 0 0 0 1.80E+08 1.76E+08 - - - 3.1485 0.9986 221125_WJC_METTL3_EV_vs_WT_F02.19235.19235.2 0.000143 13/26 R.LAYLPTAPQPFSSR.H "sp|Q9Y618|NCOR2_HUMAN,tr|C9J7T7|C9J7T7_HUMAN,tr|C9JE98|C9JE98_HUMAN,tr|H7C1J7|H7C1J7_HUMAN,tr|C9J0Q5|C9J0Q5_HUMAN,tr|A0A384DVL6|A0A384DVL6_HUMAN" 6 1546.8144 4.81 18410 19235 2 1546.818668 774.4145 Nuclear receptor corepressor 2 OS=Homo sapiens OX=9606 GN=NCOR2 PE=1 SV=3 8.75 3393.3 - 2.06E+06 - - - 2.7734 - 2.003 0.346 - 424.7 1 2 0 0.0043 14 0 0 0 2.76E+07 5.74E+06 - - - 3.3384 0.9999 221125_WJC_METTL3_EV_vs_WT_F02.19236.19236.2 2.29E-05 20-Nov R.FIYEAWQGVER[166.11].D "sp|C9JLW8|MCRI1_HUMAN,tr|I3L4Q0|I3L4Q0_HUMAN,tr|I3L2L5|I3L2L5_HUMAN,tr|I3L317|I3L317_HUMAN" 4 1406.6858 0.8 18411 19236 2 1406.685972 704.3502 Mapk-regulated corepressor-interacting protein 1 OS=Homo sapiens OX=9606 GN=MCRIP1 PE=1 SV=1 4.53 3393.4 - 1.72E+06 - - - 0.1073 - 2.071 0.532 - 349 1 2 0 0.0002 11 0 0 0 1.46E+07 1.83E+07 - - - 4.9398 1 221125_WJC_METTL3_EV_vs_WT_F02.19243.19243.3 0.000107 17/60 K.VPPAVIIPPAAPLSGR.R "sp|Q9H4A3|WNK1_HUMAN,tr|F5GWT4|F5GWT4_HUMAN,tr|A0A6Q8PFM0|A0A6Q8PFM0_HUMAN" 3 1553.9293 2.26 18416 19243 3 1553.928918 518.9837 Serine\threonine-protein kinase WNK1 OS=Homo sapiens OX=9606 GN=WNK1 PE=1 SV=2 9.72 3394.2 - 2.25E+06 - - - -0.2774 - 3.133 0.502 - 331.9 1 2 0 -0.0004 16 0 0 0 2.77E+07 1.22E+07 - - - 7.0669 0.9999 221125_WJC_METTL3_EV_vs_WT_F02.19244.19244.2 1.98E-07 13/24 R.LGSTVFVANLDYK[136.11].V "sp|P52272|HNRPM_HUMAN,tr|M0R019|M0R019_HUMAN,tr|A0A087X0X3|A0A087X0X3_HUMAN,tr|M0QYQ7|M0QYQ7_HUMAN,tr|M0R2T0|M0R2T0_HUMAN" 5 1433.7646 1.77 18417 19244 2 1433.762664 717.8896 Heterogeneous nuclear ribonucleoprotein M OS=Homo sapiens OX=9606 GN=HNRNPM PE=1 SV=3 5.83 3394.3 - 1.37E+06 - - - -1.337 - 2.92 0.458 - 749.7 1 2 0 -0.0019 13 0 0 0 2.21E+09 1.25E+09 - - - 5.1734 0.9667 221125_WJC_METTL3_EV_vs_WT_F02.19246.19246.2 0.173 18-Nov N.LQSIFNIGSR.G "sp|P43243|MATR3_HUMAN,tr|A8MXP9|A8MXP9_HUMAN,tr|D6R991|D6R991_HUMAN,tr|D6REK4|D6REK4_HUMAN,tr|A0A0R4J2E8|A0A0R4J2E8_HUMAN,tr|D6RCM3|D6RCM3_HUMAN,tr|D6R8Z5|D6R8Z5_HUMAN,tr|D6REM6|D6REM6_HUMAN" 8 1133.6193 1.47 18419 19246 2 1133.619218 567.8169 Matrin-3 OS=Homo sapiens OX=9606 GN=MATR3 PE=1 SV=2 9.75 3394.5 - 1.14E+06 - - - -0.0785 - 1.852 0.287 - 308.5 1 1 0 -0.0001 10 0 0 0 3.81E+07 2.60E+07 - - - 2.8809 0.9996 221125_WJC_METTL3_EV_vs_WT_F02.19248.19248.2 0.000364 18-Oct R.FQSLGVAFYR.G "sp|P51149|RAB7A_HUMAN,tr|C9J592|C9J592_HUMAN,tr|A0A6Q8PH84|A0A6Q8PH84_HUMAN,tr|C9J8S3|C9J8S3_HUMAN,tr|C9IZZ0|C9IZZ0_HUMAN,tr|A0A6Q8PGE6|A0A6Q8PGE6_HUMAN,tr|A0A6Q8PG52|A0A6Q8PG52_HUMAN" 7 1186.6135 1.68 18421 19248 2 1186.61128 594.314 Ras-related protein Rab-7a OS=Homo sapiens OX=9606 GN=RAB7A PE=1 SV=1 8.75 3394.8 - 1.05E+06 - - - -1.8658 - 2.034 0.416 - 274.9 1 2 0 -0.0022 10 0 0 0 3.03E+07 1.81E+07 - - - 4.0947 0.9999 221125_WJC_METTL3_EV_vs_WT_F02.19253.19253.2 0.000113 22-Nov K.EFSPFGTITSAK[136.11].V "sp|P11940|PABP1_HUMAN,tr|A0A7I2YQE4|A0A7I2YQE4_HUMAN,tr|A0A7I2V649|A0A7I2V649_HUMAN,tr|H0YB86|H0YB86_HUMAN,tr|H0YAR2|H0YAR2_HUMAN,tr|E7ERJ7|E7ERJ7_HUMAN,tr|A0A7I2YQ88|A0A7I2YQ88_HUMAN,tr|A0A087WTT1|A0A087WTT1_HUMAN,tr|H0YAP2|H0YAP2_HUMAN,tr|A0A7I2V4N4|A0A7I2V4N4_HUMAN,tr|E7EQV3|E7EQV3_HUMAN" 11 1291.654 1.07 18425 19253 2 1291.653185 646.8343 Polyadenylate-binding protein 1 OS=Homo sapiens OX=9606 GN=PABPC1 PE=1 SV=2 6.1 3395.4 - 3.70E+07 - - - -0.6062 - 2.041 0.508 - 490.3 1 2 0 -0.0008 12 0 0 0 6.17E+08 5.78E+08 - - - 4.67 1 221125_WJC_METTL3_EV_vs_WT_F02.19254.19254.2 0.172 16/22 M.PEFLEDPSVLTK.D "sp|P42166|LAP2A_HUMAN,sp|P42167|LAP2B_HUMAN,tr|G5E972|G5E972_HUMAN" 3 1373.7078 1.29 18426 19254 2 1373.705938 687.8612 "Lamina-associated polypeptide 2, isoform alpha OS=Homo sapiens OX=9606 GN=TMPO PE=1 SV=2" 4.14 3395.4 - 1.86E+07 - - - -1.3904 - 3.074 0.621 - 957.2 1 2 0 -0.0019 12 0 0 0 3.10E+08 2.41E+08 - - - 6.5819 0.9999 221125_WJC_METTL3_EV_vs_WT_F02.19255.19255.2 7.49E-05 13/22 M.PEFLEDPSVLTK[136.11].D "sp|P42166|LAP2A_HUMAN,sp|P42167|LAP2B_HUMAN,tr|G5E972|G5E972_HUMAN" 3 1381.722 1.29 18427 19255 2 1381.721823 691.8683 "Lamina-associated polypeptide 2, isoform alpha OS=Homo sapiens OX=9606 GN=TMPO PE=1 SV=2" 4.14 3395.5 - 1.47E+07 - - - -0.1628 - 2.42 0.488 - 464.6 1 2 0 -0.0002 12 0 0 0 3.10E+08 2.41E+08 - - - 4.9706 1 221125_WJC_METTL3_EV_vs_WT_F02.19256.19256.2 1.39E-08 13/20 K.TPYTIMFGPDK.C "sp|P27824|CALX_HUMAN,tr|A0A7P0T937|A0A7P0T937_HUMAN,tr|A0A7P0T840|A0A7P0T840_HUMAN,tr|D6RFL1|D6RFL1_HUMAN,tr|A0A7P0Z4H2|A0A7P0Z4H2_HUMAN,tr|A0A7P0TB65|A0A7P0TB65_HUMAN,tr|A0A7P0TAE9|A0A7P0TAE9_HUMAN,tr|D6RGY2|D6RGY2_HUMAN,tr|A0A7P0T8G1|A0A7P0T8G1_HUMAN,tr|A0A7P0Z4D6|A0A7P0Z4D6_HUMAN,tr|A0A7P0Z484|A0A7P0Z484_HUMAN,tr|A0A7P0TAR9|A0A7P0TAR9_HUMAN,tr|A0A7P0T9L0|A0A7P0T9L0_HUMAN" 13 1268.6111 1.43 18428 19256 2 1268.61196 635.3128 Calnexin OS=Homo sapiens OX=9606 GN=CANX PE=1 SV=2 5.5 3395.5 - 4.39E+06 - - - 0.67 - 2.551 0.66 - 819.9 1 2 0 0.0008 11 0 0 0 1.43E+08 9.97E+07 - - - 6.4489 0.9767 221125_WJC_METTL3_EV_vs_WT_F02.19257.19257.2 0.00145 14-Jul K.DNNLLGK[136.11]F.D "sp|P54652|HSP72_HUMAN,sp|P11142|HSP7C_HUMAN,tr|E9PNE6|E9PNE6_HUMAN,tr|A8K7Q2|A8K7Q2_HUMAN,tr|E9PKE3|E9PKE3_HUMAN,tr|E9PM13|E9PM13_HUMAN,tr|E9PS65|E9PS65_HUMAN" 7 927.4905 0.16 18429 19257 2 927.4903 464.7525 Heat shock-related 70 kDa protein 2 OS=Homo sapiens OX=9606 GN=HSPA2 PE=1 SV=1 5.84 3395.6 - 3.34E+06 - - - -0.2491 - 1.447 0.42 - 204.1 1 1 0 -0.0002 8 0 0 0 4.98E+06 3.19E+07 - - - 3.2574 0.9997 221125_WJC_METTL3_EV_vs_WT_F02.19259.19259.2 0.00615 16-Nov K.IAFAITAIK.G "sp|P62269|RS18_HUMAN,tr|A0A0G2JQH2|A0A0G2JQH2_HUMAN,tr|Q5GGW2|Q5GGW2_HUMAN" 3 946.5852 1.11 18431 19259 2 946.584013 474.2999 40S ribosomal protein S18 OS=Homo sapiens OX=9606 GN=RPS18 PE=1 SV=3 8.75 3395.8 - 1.13E+06 - - - -1.2054 - 2.22 0.365 - 289.8 1 2 0 -0.0011 9 0 0 0 1.46E+07 1.32E+07 - - - 4.0438 0.9685 221125_WJC_METTL3_EV_vs_WT_F02.19261.19261.2 1.6 14-Jul K.DLLGELSK[136.11].V "sp|Q7Z589|EMSY_HUMAN,tr|E9PMC9|E9PMC9_HUMAN" 2 881.4949 0.71 18433 19261 2 881.495197 441.7548 BRCA2-interacting transcriptional repressor EMSY OS=Homo sapiens OX=9606 GN=EMSY PE=1 SV=2 4.37 3396.1 - 967158 - - - 0.2825 - 1.322 0 - 173.4 1 2 0 0.0002 8 0 0 0 1.22E+07 1.72E+07 - - - -0.1172 0.998 221125_WJC_METTL3_EV_vs_WT_F02.19262.19262.2 0.0426 14-Aug K.FYFEELGK.Y sp|Q10471|GALT2_HUMAN 1 1031.4964 1.55 18434 19262 2 1031.497052 516.7555 Polypeptide N-acetylgalactosaminyltransferase 2 OS=Homo sapiens OX=9606 GN=GALNT2 PE=1 SV=1 4.53 3396.2 - 870546 - - - 0.634 - 1.382 0.254 - 165.6 1 2 0 0.0007 8 0 0 0 1.77E+07 1.14E+07 - - - 1.8926 1 221125_WJC_METTL3_EV_vs_WT_F02.19263.19263.2 1.64E-10 16/28 R.FDDLSGEYNPEVFDK.T sp|Q96EU6|RRP36_HUMAN 1 1773.7734 0.67 18435 19263 2 1773.767262 887.894 Ribosomal RNA processing protein 36 homolog OS=Homo sapiens OX=9606 GN=RRP36 PE=1 SV=1 3.77 3396.4 - 856378 - - - -3.4384 - 2.835 0.714 - 681.7 1 2 0 -0.0061 15 0 0 0 1.81E+07 2.71E+07 - - - 6.8746 0.9997 221125_WJC_METTL3_EV_vs_WT_F02.19265.19265.3 0.000248 Nov-44 M.PEFLEDPSVLTK[136.11].D "sp|P42166|LAP2A_HUMAN,sp|P42167|LAP2B_HUMAN,tr|G5E972|G5E972_HUMAN" 3 1381.722 1.65 18437 19265 3 1381.719207 461.5813 "Lamina-associated polypeptide 2, isoform alpha OS=Homo sapiens OX=9606 GN=TMPO PE=1 SV=2" 4.14 3396.6 - 566949 - - - -2.0561 - 2.175 0.369 - 154.7 1 2 0 -0.0028 12 0 0 0 9.21E+06 5.59E+06 - - - 4.807 0.9914 221125_WJC_METTL3_EV_vs_WT_F02.19270.19270.2 0.000103 18-Oct R.FQSLGVAFYR[166.11].G "sp|P51149|RAB7A_HUMAN,tr|C9J592|C9J592_HUMAN,tr|A0A6Q8PH84|A0A6Q8PH84_HUMAN,tr|C9J8S3|C9J8S3_HUMAN,tr|C9IZZ0|C9IZZ0_HUMAN,tr|A0A6Q8PGE6|A0A6Q8PGE6_HUMAN,tr|A0A6Q8PG52|A0A6Q8PG52_HUMAN" 7 1196.6218 2.54 18440 19270 2 1196.615274 599.3182 Ras-related protein Rab-7a OS=Homo sapiens OX=9606 GN=RAB7A PE=1 SV=1 8.75 3397.1 - 1.50E+06 - - - -5.4236 - 1.713 0.395 - 260.6 1 2 0 -0.0065 10 0 0 0 2.85E+07 1.12E+07 - - - 3.4588 0.9989 221125_WJC_METTL3_EV_vs_WT_F02.19272.19272.2 0.0204 14-Aug R.GLFIIDGK.G sp|P32119|PRDX2_HUMAN 1 861.496 0.98 18442 19272 2 861.495324 431.7553 Peroxiredoxin-2 OS=Homo sapiens OX=9606 GN=PRDX2 PE=1 SV=5 5.84 3397.3 - 1.02E+06 - - - -0.7893 - 1.478 0.291 - 258.4 1 2 0 -0.0007 8 0 0 0 1.14E+07 1.16E+07 - - - 2.3684 0.999 221125_WJC_METTL3_EV_vs_WT_F02.19273.19273.2 0.00311 14-Aug K.DLSLDDFK[136.11].G sp|P30048|PRDX3_HUMAN 1 959.4691 0.76 18443 19273 2 959.467518 480.7418 "Thioredoxin-dependent peroxide reductase, mitochondrial OS=Homo sapiens OX=9606 GN=PRDX3 PE=1 SV=3" 3.93 3397.4 - 999240 - - - -1.677 - 1.535 0.348 - 193.6 1 2 0 -0.0016 8 0 0 0 6.96E+07 9.16E+07 - - - 2.9033 0.9998 221125_WJC_METTL3_EV_vs_WT_F02.19274.19274.2 0.000143 24-Oct K.QYIISEELISEGK.W "sp|Q9UKK9|NUDT5_HUMAN,tr|A6NJU6|A6NJU6_HUMAN,tr|C9JYY9|C9JYY9_HUMAN,tr|A6NCQ0|A6NCQ0_HUMAN,tr|A6NFX8|A6NFX8_HUMAN" 5 1507.777 1.6 18444 19274 2 1507.775356 754.8958 ADP-sugar pyrophosphatase OS=Homo sapiens OX=9606 GN=NUDT5 PE=1 SV=1 4.25 3397.6 - 964923 - - - -1.0837 - 2.273 0.473 - 328.1 1 2 0 -0.0016 13 0 0 0 9.32E+06 5.83E+06 - - - 4.6414 0.9999 221125_WJC_METTL3_EV_vs_WT_F02.19276.19276.2 4.07E-08 16/32 K.VPLPSLSPTMQAGTIAR.W "sp|P10515|ODP2_HUMAN,tr|A0A7P0TBE2|A0A7P0TBE2_HUMAN,tr|A0A7P0Z4G4|A0A7P0Z4G4_HUMAN,tr|A0A7P0TAX2|A0A7P0TAX2_HUMAN,tr|A0A7P0TBK2|A0A7P0TBK2_HUMAN,tr|A0A7P0T9N8|A0A7P0T9N8_HUMAN,tr|E9PEJ4|E9PEJ4_HUMAN,tr|A0A7P0Z423|A0A7P0Z423_HUMAN,tr|A0A7P0TAG1|A0A7P0TAG1_HUMAN,tr|A0A7P0Z459|A0A7P0Z459_HUMAN,tr|H0YDD4|H0YDD4_HUMAN" 11 1737.9447 0.83 18446 19276 2 1737.943891 869.9796 "Dihydrolipoyllysine-residue acetyltransferase component of pyruvate dehydrogenase complex, mitochondrial OS=Homo sapiens OX=9606 GN=DLAT PE=1 SV=3" 9.72 3397.8 - 469155 - - - -0.4891 - 2.678 0.523 - 639.2 1 2 0 -0.0008 17 0 0 0 2.13E+07 2.56E+07 - - - 5.3255 0.8242 221125_WJC_METTL3_EV_vs_WT_F02.19280.19280.2 0.931 18-Jun K.NVSENKEIVK[136.11].L "sp|Q8TE73|DYH5_HUMAN,tr|A0A7P0Z455|A0A7P0Z455_HUMAN" 2 1166.6387 - 18448 19280 2 1166.639854 584.3266 Dynein axonemal heavy chain 5 OS=Homo sapiens OX=9606 GN=DNAH5 PE=1 SV=3 6.14 3398.2 - 7.64E+06 - - - 1.0303 - 1.227 0.106 - 85.3 1 2 1 0.0012 10 0 0 0 - - - - - 0.3946 0.9998 221125_WJC_METTL3_EV_vs_WT_F02.19282.19282.2 0.00249 16-Sep R.YLDVSILGK.F sp|Q86U44|MTA70_HUMAN 1 1006.5699 0.02 18450 19282 2 1006.569649 504.2922 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 5.83 3398.4 - 3.87E+06 - - - -0.2474 - 1.79 0.431 - 186 1 2 0 -0.0002 9 0 0 0 9.93E+08 4.43E+10 - - - 3.9087 1 221125_WJC_METTL3_EV_vs_WT_F02.19286.19286.2 1.12E-06 15/22 K.ELEEIVQPIISK[136.11].L "sp|P11021|BIP_HUMAN,tr|A0A7P0TB36|A0A7P0TB36_HUMAN,tr|A0A7P0TAI0|A0A7P0TAI0_HUMAN" 3 1404.7955 0.54 18454 19286 2 1404.792918 703.405 Endoplasmic reticulum chaperone BiP OS=Homo sapiens OX=9606 GN=HSPA5 PE=1 SV=2 4.25 3398.8 - 1.34E+06 - - - -1.8714 - 2.693 0.574 - 932.8 1 2 0 -0.0026 12 0 0 0 2.84E+08 5.28E+08 - - - 5.8863 0.9999 221125_WJC_METTL3_EV_vs_WT_F02.19288.19288.2 2.26E-06 18/32 K.VPLPSLSPTMQAGTIAR[166.11].W "sp|P10515|ODP2_HUMAN,tr|A0A7P0TBE2|A0A7P0TBE2_HUMAN,tr|A0A7P0Z4G4|A0A7P0Z4G4_HUMAN,tr|A0A7P0TAX2|A0A7P0TAX2_HUMAN,tr|A0A7P0TBK2|A0A7P0TBK2_HUMAN,tr|A0A7P0T9N8|A0A7P0T9N8_HUMAN,tr|E9PEJ4|E9PEJ4_HUMAN,tr|A0A7P0Z423|A0A7P0Z423_HUMAN,tr|A0A7P0TAG1|A0A7P0TAG1_HUMAN,tr|A0A7P0Z459|A0A7P0Z459_HUMAN,tr|H0YDD4|H0YDD4_HUMAN" 11 1747.953 0.83 18456 19288 2 1747.950887 874.9838 "Dihydrolipoyllysine-residue acetyltransferase component of pyruvate dehydrogenase complex, mitochondrial OS=Homo sapiens OX=9606 GN=DLAT PE=1 SV=3" 9.72 3399.1 - 818378 - - - -1.2151 - 2.63 0.57 - 650.3 1 2 0 -0.0021 17 0 0 0 2.13E+07 2.56E+07 - - - 5.6277 1 221125_WJC_METTL3_EV_vs_WT_F02.19294.19294.3 0.000327 18/48 R.IVYYLMNIHVQPR.T "sp|Q16875|F263_HUMAN,sp|O60825|F262_HUMAN,tr|A0A1W2PR17|A0A1W2PR17_HUMAN,tr|Q5W015|Q5W015_HUMAN,tr|F2Z2I2|F2Z2I2_HUMAN,tr|Q5VX20|Q5VX20_HUMAN" 6 1644.881 2.35 18460 19294 3 1644.881504 549.3009 "6-phosphofructo-2-kinase\fructose-2,6-bisphosphatase 3 OS=Homo sapiens OX=9606 GN=PFKFB3 PE=1 SV=1" 8.6 3399.9 - 3.76E+06 - - - 0.2955 - 3.048 0.447 - 554.6 1 2 0 0.0005 13 0 0 0 1.80E+08 7.65E+07 - - - 6.5452 0.9997 221125_WJC_METTL3_EV_vs_WT_F02.19295.19295.2 0.00787 20-Aug K.IGQPTVSYFLK.A sp|Q9Y3B7|RM11_HUMAN 1 1251.6863 2.51 18461 19295 2 1251.686781 626.8504 "39S ribosomal protein L11, mitochondrial OS=Homo sapiens OX=9606 GN=MRPL11 PE=1 SV=1" 8.59 3399.9 - 2.71E+06 - - - 0.3651 - 1.921 0.361 - 179.1 1 2 0 0.0005 11 0 0 0 5.50E+07 2.20E+07 - - - 3.4733 0.999 221125_WJC_METTL3_EV_vs_WT_F02.19298.19298.3 0.00671 Dec-48 R.LGSTVFVANLDYK.V "sp|P52272|HNRPM_HUMAN,tr|M0R019|M0R019_HUMAN,tr|A0A087X0X3|A0A087X0X3_HUMAN,tr|M0QYQ7|M0QYQ7_HUMAN,tr|M0R2T0|M0R2T0_HUMAN" 5 1425.7504 1.7 18464 19298 3 1425.750144 476.2574 Heterogeneous nuclear ribonucleoprotein M OS=Homo sapiens OX=9606 GN=HNRNPM PE=1 SV=3 5.83 3400.1 - 2.94E+06 - - - -0.1662 - 1.552 0.32 - 126.8 1 2 0 -0.0002 13 0 0 0 5.96E+07 3.50E+07 - - - 3.2993 0.9947 221125_WJC_METTL3_EV_vs_WT_F02.19299.19299.2 1.62E-05 15/26 L.LQPLNVEIDPEIQK.V sp|P04264|K2C1_HUMAN 1 1634.8879 999 18465 19299 2 1634.888005 818.4512 "Keratin, type II cytoskeletal 1 OS=Homo sapiens OX=9606 GN=KRT1 PE=1 SV=6" 4.14 3400.2 - 2.14E+06 - - - 0.0416 - 2.627 0.548 - 683.2 1 1 0 0.0001 14 0 0 0 4.02E+08 0.00E+00 - - - 5.5122 0.9645 221125_WJC_METTL3_EV_vs_WT_F02.19300.19300.2 0.0235 14-Aug R.GLFIIDDK[136.11].G "sp|Q06830|PRDX1_HUMAN,sp|Q13162|PRDX4_HUMAN,tr|A0A0A0MRQ5|A0A0A0MRQ5_HUMAN,tr|H7C3T4|H7C3T4_HUMAN,tr|A0A0A0MSI0|A0A0A0MSI0_HUMAN" 5 927.5157 0.71 18466 19300 2 927.51886 464.7651 Peroxiredoxin-1 OS=Homo sapiens OX=9606 GN=PRDX1 PE=1 SV=1 4.21 3400.3 - 1.51E+06 - - - 3.4242 - 1.899 0.002 - 259.4 1 2 0 0.0032 8 0 0 0 1.40E+08 1.98E+08 - - - 0.989 0.9999 221125_WJC_METTL3_EV_vs_WT_F02.19301.19301.3 0.00583 21/48 K.ILTPIIFKEENLR.T "sp|P82650|RT22_HUMAN,tr|G5E9W7|G5E9W7_HUMAN,tr|A0A7P0MKV3|A0A7P0MKV3_HUMAN,tr|H7C5L9|H7C5L9_HUMAN" 4 1584.9239 1.15 18467 19301 3 1584.926402 529.3153 "28S ribosomal protein S22, mitochondrial OS=Homo sapiens OX=9606 GN=MRPS22 PE=1 SV=1" 6.14 3400.4 - 973064 - - - 1.5603 - 3.835 0.46 - 870.5 1 2 1 0.0025 13 0 0 0 4.29E+07 3.72E+07 - - - 7.3123 0.9999 221125_WJC_METTL3_EV_vs_WT_F02.19304.19304.2 0.000522 22-Dec K.ELEEIVQPIISK.L "sp|P11021|BIP_HUMAN,tr|A0A7P0TB36|A0A7P0TB36_HUMAN,tr|A0A7P0TAI0|A0A7P0TAI0_HUMAN" 3 1396.7813 0.54 18468 19304 2 1396.780642 699.3979 Endoplasmic reticulum chaperone BiP OS=Homo sapiens OX=9606 GN=HSPA5 PE=1 SV=2 4.25 3400.8 - 2.87E+06 - - - -0.5047 - 2.312 0.447 - 556.4 1 2 0 -0.0007 12 0 0 0 2.84E+08 5.28E+08 - - - 4.5475 0.9999 221125_WJC_METTL3_EV_vs_WT_F02.19305.19305.2 4.68E-07 16/30 K.ELPAAEPVLSPLEGTK[136.11].M "sp|Q9BY77|PDIP3_HUMAN,tr|F6VRR5|F6VRR5_HUMAN" 2 1657.9018 1.77 18469 19305 2 1657.899676 829.9582 Polymerase delta-interacting protein 3 OS=Homo sapiens OX=9606 GN=POLDIP3 PE=1 SV=2 4.25 3401 - 3.01E+06 - - - -1.2829 - 2.735 0.529 - 595 1 2 0 -0.0021 16 0 0 0 2.74E+08 1.55E+08 - - - 5.4211 0.9914 221125_WJC_METTL3_EV_vs_WT_F02.19307.19307.2 0.123 14-Aug R.GLFIIDDK.G "sp|Q06830|PRDX1_HUMAN,sp|Q13162|PRDX4_HUMAN,tr|A0A0A0MRQ5|A0A0A0MRQ5_HUMAN,tr|H7C3T4|H7C3T4_HUMAN,tr|A0A0A0MSI0|A0A0A0MSI0_HUMAN" 5 919.5015 0.71 18471 19307 2 919.502142 460.758 Peroxiredoxin-1 OS=Homo sapiens OX=9606 GN=PRDX1 PE=1 SV=1 4.21 3401.2 - 1.64E+06 - - - 0.7156 - 1.799 0.003 - 244.3 1 2 0 0.0007 8 0 0 0 1.40E+08 1.98E+08 - - - 0.834 0.9987 221125_WJC_METTL3_EV_vs_WT_F02.19308.19308.2 0.0021 22-Nov R.IESPEEISLLPK.T "sp|P49914|MTHFS_HUMAN,tr|A0A0A6YYL1|A0A0A6YYL1_HUMAN,tr|A0A0U1RR23|A0A0U1RR23_HUMAN,tr|A0A0U1RQM3|A0A0U1RQM3_HUMAN" 4 1353.7391 3.23 18472 19308 2 1353.735675 677.8769 5-formyltetrahydrofolate cyclo-ligase OS=Homo sapiens OX=9606 GN=MTHFS PE=1 SV=2 4.25 3401.4 - 1.31E+06 - - - -2.5655 - 1.836 0.355 - 349.4 1 2 0 -0.0035 12 0 0 0 4.04E+07 1.25E+07 - - - 3.2606 1 221125_WJC_METTL3_EV_vs_WT_F02.19311.19311.2 1.38E-10 14/26 R.AVFQANQENLPILK[136.11].R sp|P05023|AT1A1_HUMAN 1 1591.8813 0.93 18475 19311 2 1591.87692 796.9479 Sodium\potassium-transporting ATPase subunit alpha-1 OS=Homo sapiens OX=9606 GN=ATP1A1 PE=1 SV=1 6.05 3401.7 - 814181 - - - -2.7778 - 2.764 0.644 - 533.7 1 2 0 -0.0044 14 0 0 0 7.34E+06 7.92E+06 - - - 6.3475 0.9993 221125_WJC_METTL3_EV_vs_WT_F02.19315.19315.2 0.0444 18-Oct K.ALDDMISTLK[136.11].K "sp|P49368|TCPG_HUMAN,tr|E9PM09|E9PM09_HUMAN,tr|Q5SZW8|Q5SZW8_HUMAN,tr|E9PRC8|E9PRC8_HUMAN,tr|B4DUR8|B4DUR8_HUMAN,tr|Q5SZX9|Q5SZX9_HUMAN,tr|E9PQ35|E9PQ35_HUMAN,tr|Q5SZX6|Q5SZX6_HUMAN" 8 1113.5831 0.25 18477 19315 2 1113.580914 557.7988 T-complex protein 1 subunit gamma OS=Homo sapiens OX=9606 GN=CCT3 PE=1 SV=4 4.21 3402.2 - 3.34E+06 - - - -1.9729 - 1.949 0.351 - 253.8 1 2 0 -0.0022 10 0 0 0 1.69E+08 6.87E+08 - - - 3.4955 0.9998 221125_WJC_METTL3_EV_vs_WT_F02.19317.19317.2 0.000194 13/18 K.IDISPVLLQK[136.11].G "sp|P49959|MRE11_HUMAN,tr|F5GXT0|F5GXT0_HUMAN,tr|F8W7U8|F8W7U8_HUMAN" 3 1132.6947 1.1 18479 19317 2 1132.694195 567.3546 Double-strand break repair protein MRE11 OS=Homo sapiens OX=9606 GN=MRE11 PE=1 SV=3 5.84 3402.4 - 2.26E+06 - - - -0.4556 - 2.093 0.417 - 289.5 1 2 0 -0.0005 10 0 0 0 4.02E+07 3.66E+07 - - - 4.1825 0.9997 221125_WJC_METTL3_EV_vs_WT_F02.19318.19318.2 0.000536 14/18 K.IDISPVLLQK.G "sp|P49959|MRE11_HUMAN,tr|F5GXT0|F5GXT0_HUMAN,tr|F8W7U8|F8W7U8_HUMAN" 3 1124.6805 1.1 18480 19318 2 1124.683404 563.3475 Double-strand break repair protein MRE11 OS=Homo sapiens OX=9606 GN=MRE11 PE=1 SV=3 5.84 3402.5 - 2.19E+06 - - - 2.5723 - 2.493 0.5 - 445 1 2 0 0.0029 10 0 0 0 4.02E+07 3.66E+07 - - - 5.2829 0.9984 221125_WJC_METTL3_EV_vs_WT_F02.19319.19319.2 0.181 13/22 K.C[160.03]PQVVISFYEER.L "sp|P83916|CBX1_HUMAN,tr|J3KS05|J3KS05_HUMAN" 2 1525.7235 5.04 18481 19319 2 1525.727513 763.869 Chromobox protein homolog 1 OS=Homo sapiens OX=9606 GN=CBX1 PE=1 SV=1 4.53 3402.6 - 1.10E+06 - - - 2.6204 - 2.366 0.241 - 488 1 2 0 0.004 12 0 0 0 2.80E+07 5.55E+06 - - - 3.0857 0.9994 221125_WJC_METTL3_EV_vs_WT_F02.19324.19324.2 0.000104 24-Oct K.YLGINSDGLVVGR[166.11].S "sp|Q14331|FRG1_HUMAN,tr|E9PRR7|E9PRR7_HUMAN" 2 1371.7386 0.8 18484 19324 2 1371.734843 686.8766 Protein FRG1 OS=Homo sapiens OX=9606 GN=FRG1 PE=1 SV=1 5.84 3403.1 - 6.43E+06 - - - -2.7272 - 1.896 0.51 - 287.7 1 2 0 -0.0037 13 0 0 0 1.23E+08 1.55E+08 - - - 4.4486 0.9993 221125_WJC_METTL3_EV_vs_WT_F02.19326.19326.2 0.00136 20-Sep K.FSPAGPILSIR[166.11].L "sp|Q9H361|PABP3_HUMAN,sp|Q5JQF8|PAP1M_HUMAN,sp|Q4VXU2|PAP1L_HUMAN,sp|P11940|PABP1_HUMAN,tr|A0A7I2V3J9|A0A7I2V3J9_HUMAN,tr|A0A7I2V649|A0A7I2V649_HUMAN,tr|A0A6Q8JFT6|A0A6Q8JFT6_HUMAN,tr|E5RHG7|E5RHG7_HUMAN,tr|E5RFD8|E5RFD8_HUMAN,tr|H0YAR2|H0YAR2_HUMAN,tr|E7ERJ7|E7ERJ7_HUMAN,tr|E5RJB9|E5RJB9_HUMAN,tr|A0A7I2YQ88|A0A7I2YQ88_HUMAN,tr|E5RGC4|E5RGC4_HUMAN,tr|E5RH24|E5RH24_HUMAN,tr|H0YBN4|H0YBN4_HUMAN,tr|A0A087WTT1|A0A087WTT1_HUMAN,tr|A0A7I2YQ90|A0A7I2YQ90_HUMAN,tr|A0A6Q8JFV4|A0A6Q8JFV4_HUMAN" 19 1166.6687 1.6 18486 19326 2 1166.667317 584.3416 Polyadenylate-binding protein 3 OS=Homo sapiens OX=9606 GN=PABPC3 PE=1 SV=2 9.75 3403.2 - 5.29E+06 - - - -1.1974 - 1.565 0.357 - 280.2 1 2 0 -0.0014 11 0 0 0 7.52E+08 4.70E+08 - - - 2.889 0.9998 221125_WJC_METTL3_EV_vs_WT_F02.19327.19327.2 1.74E-05 15/28 K.TAVTTVPSMGIGLVK[136.11].G sp|Q8WUH6|TM263_HUMAN 1 1480.8415 1.02 18487 19327 2 1480.83916 741.428 Transmembrane protein 263 OS=Homo sapiens OX=9606 GN=TMEM263 PE=1 SV=1 8.41 3403.2 - 5.08E+06 - - - -1.5471 - 2.23 0.476 - 330.8 1 2 0 -0.0023 15 0 0 0 1.10E+08 1.08E+08 - - - 4.5278 1 221125_WJC_METTL3_EV_vs_WT_F02.19328.19328.3 5.16E-07 21/48 R.IVYYLMNIHVQPR[166.11].T "sp|Q16875|F263_HUMAN,sp|O60825|F262_HUMAN,tr|A0A1W2PR17|A0A1W2PR17_HUMAN,tr|Q5W015|Q5W015_HUMAN,tr|F2Z2I2|F2Z2I2_HUMAN,tr|Q5VX20|Q5VX20_HUMAN" 6 1654.8893 2.49 18488 19328 3 1654.888461 552.637 "6-phosphofructo-2-kinase\fructose-2,6-bisphosphatase 3 OS=Homo sapiens OX=9606 GN=PFKFB3 PE=1 SV=1" 8.6 3403.3 - 3.96E+06 - - - -0.4997 - 3.13 0.511 - 712.3 1 2 0 -0.0008 13 0 0 0 2.07E+08 8.29E+07 - - - 7.3306 0.9998 221125_WJC_METTL3_EV_vs_WT_F02.19329.19329.2 9.82E-08 13/22 R.NFWVSGLSSTTR.A sp|Q15424|SAFB1_HUMAN 1 1353.6677 1.37 18489 19329 2 1353.666236 677.8411 Scaffold attachment factor B1 OS=Homo sapiens OX=9606 GN=SAFB PE=1 SV=4 9.75 3403.4 - 2.45E+06 - - - -1.0918 - 2.306 0.416 - 656.8 1 2 0 -0.0015 12 0 0 0 8.07E+07 5.91E+07 - - - 4.3115 0.9998 221125_WJC_METTL3_EV_vs_WT_F02.19334.19334.2 2.20E-05 13/22 R.GLGLSPDLVVC[160.03]R[166.11].C "sp|P17812|PYRG1_HUMAN,tr|A0A3B3ITF6|A0A3B3ITF6_HUMAN,tr|B4E1E0|B4E1E0_HUMAN,tr|A0A3B3IRQ8|A0A3B3IRQ8_HUMAN,tr|A0A3B3ITB8|A0A3B3ITB8_HUMAN,tr|A0A3B3IRI2|A0A3B3IRI2_HUMAN" 6 1294.6943 0.76 18492 19334 2 1294.694695 648.3544 CTP synthase 1 OS=Homo sapiens OX=9606 GN=CTPS1 PE=1 SV=2 5.83 3404.1 - 4.36E+06 - - - 0.3229 - 2.682 0.359 - 710.6 1 2 0 0.0004 12 0 0 0 7.81E+07 1.03E+08 - - - 4.2883 0.9996 221125_WJC_METTL3_EV_vs_WT_F02.19337.19337.2 0.00105 14-Aug K.DLSLDDFK.G sp|P30048|PRDX3_HUMAN 1 951.4549 0.76 18495 19337 2 951.454076 476.7347 "Thioredoxin-dependent peroxide reductase, mitochondrial OS=Homo sapiens OX=9606 GN=PRDX3 PE=1 SV=3" 3.93 3404.3 - 3.70E+06 - - - -0.8944 - 1.59 0.398 - 211.5 1 2 0 -0.0009 8 0 0 0 6.96E+07 9.16E+07 - - - 3.379 1 221125_WJC_METTL3_EV_vs_WT_F02.19339.19339.2 2.78E-09 24-Dec A.GMGMEGIGFGINK[136.11].M "sp|P52272|HNRPM_HUMAN,tr|M0QYL3|M0QYL3_HUMAN,tr|A0A087X0X3|A0A087X0X3_HUMAN,tr|M0QZM1|M0QZM1_HUMAN" 4 1317.6301 0.96 18497 19339 2 1317.631378 659.8223 Heterogeneous nuclear ribonucleoprotein M OS=Homo sapiens OX=9606 GN=HNRNPM PE=1 SV=3 6 3404.5 - 1.02E+06 - - - 0.9866 - 2.517 0.589 - 516.2 1 1 0 0.0013 13 0 0 0 1.97E+07 2.06E+07 - - - 5.76 0.9998 221125_WJC_METTL3_EV_vs_WT_F02.19344.19344.2 0.00231 13/20 K.LNAFGNAFLNR.F "sp|Q9NZN3|EHD3_HUMAN,sp|Q9H4M9|EHD1_HUMAN,tr|C9JC03|C9JC03_HUMAN,tr|C9JIJ3|C9JIJ3_HUMAN,tr|C9IZH1|C9IZH1_HUMAN,tr|A0A024R571|A0A024R571_HUMAN" 6 1235.6411 1.21 18500 19344 2 1235.640446 618.8278 EH domain-containing protein 3 OS=Homo sapiens OX=9606 GN=EHD3 PE=1 SV=2 9.75 3405.1 - 2.14E+06 - - - -0.5333 - 2.326 0.41 - 527.9 1 2 0 -0.0007 11 0 0 0 4.97E+07 4.11E+07 - - - 4.3527 0.9999 221125_WJC_METTL3_EV_vs_WT_F02.19345.19345.3 0.0018 Nov-44 K.ELEEIVQPIISK[136.11].L "sp|P11021|BIP_HUMAN,tr|A0A7P0TB36|A0A7P0TB36_HUMAN,tr|A0A7P0TAI0|A0A7P0TAI0_HUMAN" 3 1404.7955 0.55 18501 19345 3 1404.794674 469.2725 Endoplasmic reticulum chaperone BiP OS=Homo sapiens OX=9606 GN=HSPA5 PE=1 SV=2 4.25 3405.3 - 1.30E+06 - - - -0.6214 - 2.307 0.373 - 288.1 1 2 0 -0.0009 12 0 0 0 1.25E+07 2.28E+07 - - - 5.0155 0.9919 221125_WJC_METTL3_EV_vs_WT_F02.19347.19347.2 0.133 16-Aug K.ALQFLEEVK[136.11].V sp|P40227|TCPZ_HUMAN 1 1083.6056 0.45 18502 19347 2 1083.603977 542.8101 T-complex protein 1 subunit zeta OS=Homo sapiens OX=9606 GN=CCT6A PE=1 SV=3 4.53 3405.5 - 7.01E+06 - - - -1.4618 - 1.477 0.12 - 161 1 2 0 -0.0016 9 0 0 0 9.70E+08 2.13E+09 - - - 1.0552 0.999 221125_WJC_METTL3_EV_vs_WT_F02.19350.19350.2 0.00055 20-Oct R.AELLSLTQMER.E "sp|P14373|TRI27_HUMAN,tr|A0A0G2JIZ4|A0A0G2JIZ4_HUMAN" 2 1289.6649 13.13 18503 19350 2 1289.663614 645.8397 Zinc finger protein RFP OS=Homo sapiens OX=9606 GN=TRIM27 PE=1 SV=1 4.53 3405.9 - 2.97E+06 - - - -1.0258 - 2.02 0.212 - 387.5 1 2 0 -0.0013 11 0 0 0 6.04E+07 4.61E+06 - - - 2.5085 0.9999 221125_WJC_METTL3_EV_vs_WT_F02.19351.19351.2 0.00094 13/22 K.FTQLDLEDVQVR.E "sp|Q9NTJ3|SMC4_HUMAN,tr|E9PD53|E9PD53_HUMAN,tr|C9JR83|C9JR83_HUMAN" 3 1461.7464 0.86 18504 19351 2 1461.746313 731.8805 Structural maintenance of chromosomes protein 4 OS=Homo sapiens OX=9606 GN=SMC4 PE=1 SV=2 4.03 3406 - 1.99E+06 - - - -0.0308 - 2.461 0.45 - 564.5 1 2 0 0 12 0 0 0 4.43E+07 5.15E+07 - - - 4.7342 0.9961 221125_WJC_METTL3_EV_vs_WT_F02.19352.19352.2 0.0586 16-Sep K.NIVPGWLQR[166.11].Y sp|P49790|NU153_HUMAN 1 1091.6115 4.49 18505 19352 2 1091.610533 546.813 Nuclear pore complex protein Nup153 OS=Homo sapiens OX=9606 GN=NUP153 PE=1 SV=2 9.75 3406 - 7.37E+06 - - - -0.9161 - 1.573 0.141 - 292 1 2 0 -0.001 9 0 0 0 8.46E+08 1.88E+08 - - - 1.3926 0.9998 221125_WJC_METTL3_EV_vs_WT_F02.19353.19353.2 0.000122 18-Nov K.ALDDMISTLK.K "sp|P49368|TCPG_HUMAN,tr|E9PM09|E9PM09_HUMAN,tr|Q5SZW8|Q5SZW8_HUMAN,tr|E9PRC8|E9PRC8_HUMAN,tr|B4DUR8|B4DUR8_HUMAN,tr|Q5SZX9|Q5SZX9_HUMAN,tr|E9PQ35|E9PQ35_HUMAN,tr|Q5SZX6|Q5SZX6_HUMAN" 8 1105.5689 0.25 18506 19353 2 1105.567578 553.7917 T-complex protein 1 subunit gamma OS=Homo sapiens OX=9606 GN=CCT3 PE=1 SV=4 4.21 3406.1 - 6.24E+06 - - - -1.2057 - 2.072 0.464 - 321.6 1 2 0 -0.0013 10 0 0 0 1.69E+08 6.88E+08 - - - 4.5012 0.9997 221125_WJC_METTL3_EV_vs_WT_F02.19354.19354.2 1.29E-05 22-Dec R.GLGLSPDLVVC[160.03]R.C "sp|P17812|PYRG1_HUMAN,tr|A0A3B3ITF6|A0A3B3ITF6_HUMAN,tr|B4E1E0|B4E1E0_HUMAN,tr|A0A3B3IRQ8|A0A3B3IRQ8_HUMAN,tr|A0A3B3ITB8|A0A3B3ITB8_HUMAN,tr|A0A3B3IRI2|A0A3B3IRI2_HUMAN" 6 1284.686 0.76 18507 19354 2 1284.683364 643.3503 CTP synthase 1 OS=Homo sapiens OX=9606 GN=CTPS1 PE=1 SV=2 5.83 3406.1 - 4.08E+06 - - - -2.0573 - 2.477 0.471 - 564.6 1 2 0 -0.0026 12 0 0 0 7.81E+07 1.03E+08 - - - 4.9056 0.9999 221125_WJC_METTL3_EV_vs_WT_F02.19357.19357.2 5.51E-06 22-Dec K.AITGFDDPFSGK.T sp|P15924|DESP_HUMAN 1 1253.5928 10.33 18509 19357 2 1253.591035 627.8037 Desmoplakin OS=Homo sapiens OX=9606 GN=DSP PE=1 SV=3 4.21 3406.5 - 2.55E+06 - - - -1.4223 - 2.383 0.541 - 436.1 1 2 0 -0.0018 12 0 0 0 1.95E+08 1.89E+07 - - - 5.3211 0.9996 221125_WJC_METTL3_EV_vs_WT_F02.19362.19362.2 0.000722 13/22 K.GVLLFGPPGTGK[136.11].T "sp|P35998|PRS7_HUMAN,tr|C9JX88|C9JX88_HUMAN" 2 1149.6637 0.57 18513 19362 2 1149.660974 575.8391 26S proteasome regulatory subunit 7 OS=Homo sapiens OX=9606 GN=PSMC2 PE=1 SV=3 8.75 3407 - 1.39E+06 - - - -2.4103 - 2.321 0.47 - 375.6 1 2 0 -0.0028 12 0 0 0 2.07E+07 3.63E+07 - - - 4.727 1 221125_WJC_METTL3_EV_vs_WT_F02.19364.19364.2 4.72E-07 15/30 K.ELPAAEPVLSPLEGTK.M "sp|Q9BY77|PDIP3_HUMAN,tr|F6VRR5|F6VRR5_HUMAN" 2 1649.8876 1.77 18514 19364 2 1649.884984 825.9511 Polymerase delta-interacting protein 3 OS=Homo sapiens OX=9606 GN=POLDIP3 PE=1 SV=2 4.25 3407.2 - 8.83E+06 - - - -1.5874 - 2.834 0.568 - 421.7 1 2 0 -0.0026 16 0 0 0 2.74E+08 1.55E+08 - - - 5.7965 0.9998 221125_WJC_METTL3_EV_vs_WT_F02.19366.19366.2 1.30E-06 13/20 K.NQALFPAC[160.03]VLK[136.11].N "sp|Q92499|DDX1_HUMAN,tr|A0A7I2V2M5|A0A7I2V2M5_HUMAN,tr|A0A087X2G1|A0A087X2G1_HUMAN,tr|A0A7I2V430|A0A7I2V430_HUMAN,tr|A0A7I2V421|A0A7I2V421_HUMAN,tr|A0A7I2V4F0|A0A7I2V4F0_HUMAN,tr|A0A7I2V5X8|A0A7I2V5X8_HUMAN,tr|A0A7I2V4J3|A0A7I2V4J3_HUMAN,tr|A0A087WZ71|A0A087WZ71_HUMAN,tr|A0A7I2YQ77|A0A7I2YQ77_HUMAN" 10 1267.6838 0.54 18515 19366 2 1267.681658 634.8492 ATP-dependent RNA helicase DDX1 OS=Homo sapiens OX=9606 GN=DDX1 PE=1 SV=2 8.22 3407.4 - 3.26E+06 - - - -1.7126 - 2.251 0.547 - 739.6 1 2 0 -0.0022 11 0 0 0 4.47E+07 8.34E+07 - - - 5.2754 1 221125_WJC_METTL3_EV_vs_WT_F02.19372.19372.2 1.66E-08 13/24 R.LGSTVFVANLDYK.V "sp|P52272|HNRPM_HUMAN,tr|M0R019|M0R019_HUMAN,tr|A0A087X0X3|A0A087X0X3_HUMAN,tr|M0QYQ7|M0QYQ7_HUMAN,tr|M0R2T0|M0R2T0_HUMAN" 5 1425.7504 1.77 18519 19372 2 1425.749566 713.8825 Heterogeneous nuclear ribonucleoprotein M OS=Homo sapiens OX=9606 GN=HNRNPM PE=1 SV=3 5.83 3408.1 - 1.05E+07 - - - -0.5716 - 2.957 0.55 - 664.5 1 2 0 -0.0008 13 0 0 0 2.21E+09 1.25E+09 - - - 5.8856 0.9085 221125_WJC_METTL3_EV_vs_WT_F02.19373.19373.2 0.00814 13/22 K.MALLASNSC[160.03]FIR.C "sp|Q14331|FRG1_HUMAN,tr|E9PLY7|E9PLY7_HUMAN,tr|E9PRR7|E9PRR7_HUMAN" 3 1381.6846 0.27 18520 19373 2 1382.682627 691.8496 Protein FRG1 OS=Homo sapiens OX=9606 GN=FRG1 PE=1 SV=1 8 3408.2 - 2.46E+06 - - - 722.3067 - 2.465 0.341 - 587.6 1 2 0 0.998 12 0 0 0 2.02E+07 7.47E+07 - - - 3.6201 0.9952 221125_WJC_METTL3_EV_vs_WT_F02.19374.19374.2 0.000269 14-Jul R.GPSWDPFR.D "sp|P04792|HSPB1_HUMAN,tr|A0A6Q8PGY2|A0A6Q8PGY2_HUMAN,tr|A0A6Q8PHJ6|A0A6Q8PHJ6_HUMAN,tr|A0A6Q8PHA6|A0A6Q8PHA6_HUMAN,tr|A0A6Q8PF43|A0A6Q8PF43_HUMAN,tr|A0A6Q8PFK8|A0A6Q8PFK8_HUMAN,tr|A0A6Q8PGK1|A0A6Q8PGK1_HUMAN,tr|A0A6Q8PH65|A0A6Q8PH65_HUMAN,tr|A0A6Q8PFE7|A0A6Q8PFE7_HUMAN" 9 960.4454 1.61 18521 19374 2 960.441278 481.23 Heat shock protein beta-1 OS=Homo sapiens OX=9606 GN=HSPB1 PE=1 SV=2 5.84 3408.3 - 1.89E+06 - - - -4.2564 - 1.43 0.415 - 172.4 1 2 0 -0.0041 8 0 0 0 1.93E+08 1.20E+08 - - - 3.1836 1 221125_WJC_METTL3_EV_vs_WT_F02.19375.19375.2 6.83E-08 22/32 R.AIVAIENPADVSVISSR[166.11].N "sp|P08865|RSSA_HUMAN,tr|C9J9K3|C9J9K3_HUMAN,tr|A0A0C4DG17|A0A0C4DG17_HUMAN,tr|F8WD59|F8WD59_HUMAN" 4 1749.95 0.73 18522 19375 2 1749.949255 875.9823 40S ribosomal protein SA OS=Homo sapiens OX=9606 GN=RPSA PE=1 SV=4 4.37 3408.5 - 1.54E+06 - - - -0.4452 - 3.538 0.577 - 1716.3 1 2 0 -0.0008 17 0 0 0 1.83E+08 2.50E+08 - - - 6.409 0.9999 221125_WJC_METTL3_EV_vs_WT_F02.19376.19376.2 0.000189 16/28 R.MATEVAADALGEEWK.G "sp|P62753|RS6_HUMAN,tr|A2A3R5|A2A3R5_HUMAN,tr|A2A3R7|A2A3R7_HUMAN" 3 1619.7501 1 18523 19376 2 1619.748798 810.8823 40S ribosomal protein S6 OS=Homo sapiens OX=9606 GN=RPS6 PE=1 SV=1 4 3408.6 - 1.49E+06 - - - -0.818 - 3.426 0.49 - 756.4 1 2 0 -0.0013 15 0 0 0 1.51E+08 1.51E+08 - - - 5.6872 0.9856 221125_WJC_METTL3_EV_vs_WT_F02.19377.19377.2 3.50E-05 20-Nov R.SLEAYFAVQPR.P sp|Q01851|PO4F1_HUMAN 1 1279.6561 0.61 18524 19377 2 1279.65404 640.8353 "POU domain, class 4, transcription factor 1 OS=Homo sapiens OX=9606 GN=POU4F1 PE=1 SV=4" 5.72 3408.7 - 1.28E+06 - - - -1.5996 - 2.388 0.423 - 506.9 1 1 0 -0.002 11 0 0 0 3.40E+07 5.58E+07 - - - 4.5194 0.9997 221125_WJC_METTL3_EV_vs_WT_F02.19378.19378.2 0.0128 14-Aug R.GPSWDPFR[166.11].D "sp|P04792|HSPB1_HUMAN,tr|A0A6Q8PGY2|A0A6Q8PGY2_HUMAN,tr|A0A6Q8PHJ6|A0A6Q8PHJ6_HUMAN,tr|A0A6Q8PHA6|A0A6Q8PHA6_HUMAN,tr|A0A6Q8PF43|A0A6Q8PF43_HUMAN,tr|A0A6Q8PFK8|A0A6Q8PFK8_HUMAN,tr|A0A6Q8PGK1|A0A6Q8PGK1_HUMAN,tr|A0A6Q8PH65|A0A6Q8PH65_HUMAN,tr|A0A6Q8PFE7|A0A6Q8PFE7_HUMAN" 9 970.4536 1.61 18525 19378 2 970.453593 486.2341 Heat shock protein beta-1 OS=Homo sapiens OX=9606 GN=HSPB1 PE=1 SV=2 5.84 3408.9 - 931983 - - - -0.0443 - 1.795 0.402 - 302.6 1 2 0 0 8 0 0 0 1.93E+08 1.20E+08 - - - 3.7745 0.9998 221125_WJC_METTL3_EV_vs_WT_F02.19380.19380.2 0.00258 16-Oct R.YLDVSILGK[136.11].F sp|Q86U44|MTA70_HUMAN 1 1014.5841 0.02 18526 19380 2 1014.583487 508.2993 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 5.83 3409.1 - 6.55E+08 - - - -0.6022 - 1.916 0.482 - 237.7 1 2 0 -0.0006 9 0 0 0 9.93E+08 4.43E+10 - - - 4.482 0.9997 221125_WJC_METTL3_EV_vs_WT_F02.19382.19382.2 0.0207 18-Oct K.LTLSALVDGK[136.11].S "sp|P45880|VDAC2_HUMAN,tr|A0A0A0MR02|A0A0A0MR02_HUMAN" 2 1023.6056 57.54 18527 19382 2 1023.603944 512.8101 Voltage-dependent anion-selective channel protein 2 OS=Homo sapiens OX=9606 GN=VDAC2 PE=1 SV=2 5.84 3409.3 - 2.22E+07 - - - -1.5797 - 2.176 0.381 - 312.8 1 2 0 -0.0016 10 0 0 0 2.44E+10 4.25E+08 - - - 4.0248 1 221125_WJC_METTL3_EV_vs_WT_F02.19383.19383.2 2.68E-10 18/28 R.YINENLIVNTDELGR[166.11].D "sp|P17987|TCPA_HUMAN,tr|F5H136|F5H136_HUMAN,tr|F5H7Y1|F5H7Y1_HUMAN,tr|E7ERF2|E7ERF2_HUMAN" 4 1771.898 0.44 18528 19383 2 1771.894407 886.9563 T-complex protein 1 subunit alpha OS=Homo sapiens OX=9606 GN=TCP1 PE=1 SV=1 4.14 3409.4 - 3.80E+06 - - - -2.0266 - 3.617 0.618 - 1163.8 1 2 0 -0.0036 15 0 0 0 1.86E+08 4.23E+08 - - - 6.7652 0.9998 221125_WJC_METTL3_EV_vs_WT_F02.19384.19384.2 0.000293 18-Oct R.DYTYEELLNR.V sp|P20042|IF2B_HUMAN 1 1314.6092 0.88 18529 19384 2 1314.610027 658.3119 Eukaryotic translation initiation factor 2 subunit 2 OS=Homo sapiens OX=9606 GN=EIF2S2 PE=1 SV=2 4.14 3409.5 - 3.15E+06 - - - 0.6321 - 1.985 0.428 - 404.8 1 2 0 0.0008 10 0 0 0 6.10E+07 6.93E+07 - - - 4.1157 0.9996 221125_WJC_METTL3_EV_vs_WT_F02.19388.19388.2 0.000351 18-Oct R.DYTYEELLNR[166.11].V sp|P20042|IF2B_HUMAN 1 1324.6175 0.88 18531 19388 2 1324.61539 663.316 Eukaryotic translation initiation factor 2 subunit 2 OS=Homo sapiens OX=9606 GN=EIF2S2 PE=1 SV=2 4.14 3410 - 4.53E+06 - - - -1.5672 - 1.844 0.395 - 404.9 1 2 0 -0.0021 10 0 0 0 6.10E+07 6.93E+07 - - - 3.6659 1 221125_WJC_METTL3_EV_vs_WT_F02.19389.19389.2 7.66E-06 13/20 K.WC[160.03]EYGLTFTEK[136.11].W "sp|P45880|VDAC2_HUMAN,tr|A2A3S1|A2A3S1_HUMAN,tr|Q5JSD1|Q5JSD1_HUMAN,tr|Q5JSD2|Q5JSD2_HUMAN,tr|A0A0A0MR02|A0A0A0MR02_HUMAN" 5 1440.6475 1.06 18532 19389 2 1440.646067 721.331 Voltage-dependent anion-selective channel protein 2 OS=Homo sapiens OX=9606 GN=VDAC2 PE=1 SV=2 4.53 3410.1 - 3.18E+06 - - - -0.9968 - 2.551 0.607 - 571.9 1 2 0 -0.0014 11 0 0 0 7.88E+07 7.44E+07 - - - 6.0573 0.9988 221125_WJC_METTL3_EV_vs_WT_F02.19391.19391.2 8.93E-07 20-Nov K.WC[160.03]EYGLTFTEK.W "sp|P45880|VDAC2_HUMAN,tr|A2A3S1|A2A3S1_HUMAN,tr|Q5JSD1|Q5JSD1_HUMAN,tr|Q5JSD2|Q5JSD2_HUMAN,tr|A0A0A0MR02|A0A0A0MR02_HUMAN" 5 1432.6333 1.06 18534 19391 2 1432.626894 717.3239 Voltage-dependent anion-selective channel protein 2 OS=Homo sapiens OX=9606 GN=VDAC2 PE=1 SV=2 4.53 3410.3 - 3.48E+06 - - - -4.4736 - 2.361 0.558 - 381 1 2 0 -0.0064 11 0 0 0 7.88E+07 7.44E+07 - - - 5.4844 1 221125_WJC_METTL3_EV_vs_WT_F02.19392.19392.3 1.63E-05 17/56 R.YINENLIVNTDELGR[166.11].D "sp|P17987|TCPA_HUMAN,tr|F5H136|F5H136_HUMAN,tr|F5H7Y1|F5H7Y1_HUMAN,tr|E7ERF2|E7ERF2_HUMAN" 4 1771.898 0.41 18535 19392 3 1771.894972 591.6399 T-complex protein 1 subunit alpha OS=Homo sapiens OX=9606 GN=TCP1 PE=1 SV=1 4.14 3410.4 - 2.79E+06 - - - -1.7078 - 2.934 0.451 - 466.3 1 2 0 -0.003 15 0 0 0 7.87E+07 1.91E+08 - - - 6.376 0.9999 221125_WJC_METTL3_EV_vs_WT_F02.19393.19393.2 1.72E-08 14/28 R.YINENLIVNTDELGR.D "sp|P17987|TCPA_HUMAN,tr|F5H136|F5H136_HUMAN,tr|F5H7Y1|F5H7Y1_HUMAN,tr|E7ERF2|E7ERF2_HUMAN" 4 1761.8897 0.44 18536 19393 2 1761.887191 881.9521 T-complex protein 1 subunit alpha OS=Homo sapiens OX=9606 GN=TCP1 PE=1 SV=1 4.14 3410.5 - 2.40E+06 - - - -1.4399 - 3.208 0.459 - 579.9 1 2 0 -0.0025 15 0 0 0 1.86E+08 4.24E+08 - - - 5.2962 0.9996 221125_WJC_METTL3_EV_vs_WT_F02.19394.19394.2 0.11 14/22 K.GAIIQLATGELK.R sp|P0C7T5|ATX1L_HUMAN 1 1212.7078 1.24 18537 19394 2 1212.710801 607.3612 Ataxin-1-like OS=Homo sapiens OX=9606 GN=ATXN1L PE=1 SV=1 6 3410.7 - 2.22E+06 - - - 2.4845 - 2.617 0.434 - 409.3 1 2 0 0.003 12 0 0 0 2.77E+07 2.24E+07 - - - 4.7768 0.9999 221125_WJC_METTL3_EV_vs_WT_F02.19397.19397.2 1.18E-07 14/26 K.ITLETDEDMVTEIR[166.11].L sp|Q15393|SF3B3_HUMAN 1 1673.8057 1.09 18540 19397 2 1673.803476 837.9101 Splicing factor 3B subunit 3 OS=Homo sapiens OX=9606 GN=SF3B3 PE=1 SV=4 3.83 3411.1 - 1.13E+06 - - - -1.3508 - 2.652 0.57 - 841 1 2 0 -0.0023 14 0 0 0 2.89E+07 2.65E+07 - - - 5.6978 0.9996 221125_WJC_METTL3_EV_vs_WT_F02.19399.19399.2 9.63E-06 14/26 K.ITLETDEDMVTEIR.L sp|Q15393|SF3B3_HUMAN 1 1663.7975 1.09 18542 19399 2 1663.792739 832.906 Splicing factor 3B subunit 3 OS=Homo sapiens OX=9606 GN=SF3B3 PE=1 SV=4 3.83 3411.3 - 1.25E+06 - - - -2.8417 - 2.623 0.536 - 804 1 2 0 -0.0047 14 0 0 0 2.89E+07 2.65E+07 - - - 5.4183 1 221125_WJC_METTL3_EV_vs_WT_F02.19402.19402.2 6.61E-08 17/28 R.MATEVAADALGEEWK[136.11].G "sp|P62753|RS6_HUMAN,tr|A2A3R5|A2A3R5_HUMAN,tr|A2A3R7|A2A3R7_HUMAN" 3 1627.7643 1 18543 19402 2 1627.761881 814.8894 40S ribosomal protein S6 OS=Homo sapiens OX=9606 GN=RPS6 PE=1 SV=1 4 3411.7 - 9.31E+06 - - - -1.5002 - 3.4 0.631 - 1299.5 1 2 0 -0.0024 15 0 0 0 1.51E+08 1.51E+08 - - - 6.7095 1 221125_WJC_METTL3_EV_vs_WT_F02.19403.19403.3 3.67E-05 16/56 R.MATEVAADALGEEWK[136.11].G "sp|P62753|RS6_HUMAN,tr|A2A3R5|A2A3R5_HUMAN,tr|A2A3R7|A2A3R7_HUMAN" 3 1627.7643 1.32 18544 19403 3 1627.760794 543.5954 40S ribosomal protein S6 OS=Homo sapiens OX=9606 GN=RPS6 PE=1 SV=1 4 3411.7 - 5.71E+06 - - - -2.168 - 3.25 0.529 - 290.7 1 2 0 -0.0035 15 0 0 0 8.75E+07 6.63E+07 - - - 7.5124 0.9686 221125_WJC_METTL3_EV_vs_WT_F02.19404.19404.2 0.000631 28-Oct K.FDSEPSAVALELPTR[166.11].A sp|P18583|SON_HUMAN 1 1640.8285 4.98 18545 19404 2 1640.816319 821.4215 Protein SON OS=Homo sapiens OX=9606 GN=SON PE=1 SV=4 4.14 3411.8 - 4.15E+06 - - - -7.4371 - 1.771 0.41 - 145.6 1 2 0 -0.0122 15 0 0 0 1.55E+08 3.11E+07 - - - 3.4706 1 221125_WJC_METTL3_EV_vs_WT_F02.19405.19405.2 6.26E-09 18/32 R.AIVAIENPADVSVISSR.N "sp|P08865|RSSA_HUMAN,tr|C9J9K3|C9J9K3_HUMAN,tr|A0A0C4DG17|A0A0C4DG17_HUMAN,tr|F8WD59|F8WD59_HUMAN" 4 1739.9418 0.73 18546 19405 2 1739.941443 870.9782 40S ribosomal protein SA OS=Homo sapiens OX=9606 GN=RPSA PE=1 SV=4 4.37 3411.9 - 3.74E+06 - - - -0.1845 - 3.561 0.567 - 1002.1 1 2 0 -0.0003 17 0 0 0 1.83E+08 2.50E+08 - - - 6.3512 0.9297 221125_WJC_METTL3_EV_vs_WT_F02.19406.19406.2 0.00775 20-Sep R.GVVQLFNAVQK[136.11].H sp|Q9Y3B9|RRP15_HUMAN 1 1209.6961 1.48 18547 19406 2 1209.705447 605.8553 RRP15-like protein OS=Homo sapiens OX=9606 GN=RRP15 PE=1 SV=2 8.75 3411.9 - 3.06E+06 - - - 7.7201 - 1.426 0.351 - 234.4 1 2 0 0.0093 11 0 0 0 7.49E+07 5.07E+07 - - - 2.5906 1 221125_WJC_METTL3_EV_vs_WT_F02.19407.19407.2 3.11E-07 18/30 K.ILNVGDIGGNETVTLR.Q sp|P22735|TGM1_HUMAN 1 1669.8999 999 18548 19407 2 1669.897284 835.9572 Protein-glutamine gamma-glutamyltransferase K OS=Homo sapiens OX=9606 GN=TGM1 PE=1 SV=4 4.37 3412 - 2.89E+06 - - - -1.566 - 3.35 0.565 - 1097.6 1 2 0 -0.0026 16 0 0 0 5.67E+07 0.00E+00 - - - 6.1856 1 221125_WJC_METTL3_EV_vs_WT_F02.19409.19409.2 2.41E-11 17/24 K.MPAC[160.03]NIMLLGAQR.K "sp|Q8WWY3|PRP31_HUMAN,tr|E7EVX8|E7EVX8_HUMAN,tr|E7EU94|E7EU94_HUMAN,tr|E7ESX0|E7ESX0_HUMAN,tr|E7EN72|E7EN72_HUMAN" 5 1473.7254 2.66 18550 19409 2 1473.724082 737.87 U4\U6 small nuclear ribonucleoprotein Prp31 OS=Homo sapiens OX=9606 GN=PRPF31 PE=1 SV=2 8 3412.1 - 2.44E+06 - - - -0.9255 - 3.254 0.667 - 1364.5 1 2 0 -0.0014 13 0 0 0 5.20E+07 1.96E+07 - - - 6.9952 0.9814 221125_WJC_METTL3_EV_vs_WT_F02.19410.19410.2 0.000756 14/30 R.EALATLKPQAGLIVPQ.A "sp|Q9UMS4|PRP19_HUMAN,tr|F5GY56|F5GY56_HUMAN,tr|F5H2I0|F5H2I0_HUMAN" 3 1647.956 1.28 18551 19410 2 1647.953787 824.9853 Pre-mRNA-processing factor 19 OS=Homo sapiens OX=9606 GN=PRPF19 PE=1 SV=1 6.1 3412.3 - 1.71E+06 - - - -1.3168 - 2.141 0.408 - 251.6 1 1 0 -0.0022 16 0 0 0 2.11E+07 1.65E+07 - - - 3.9254 0.9993 221125_WJC_METTL3_EV_vs_WT_F02.19411.19411.2 0.00239 18-Oct K.AISSDMFFGR[166.11].E "sp|Q8N6H7|ARFG2_HUMAN,tr|E9PMU9|E9PMU9_HUMAN,tr|H0YDN9|H0YDN9_HUMAN,tr|G5E9L0|G5E9L0_HUMAN,tr|A0A0D9SF70|A0A0D9SF70_HUMAN" 5 1139.5309 1.18 18552 19411 2 1139.529121 570.7727 ADP-ribosylation factor GTPase-activating protein 2 OS=Homo sapiens OX=9606 GN=ARFGAP2 PE=1 SV=1 5.88 3412.4 - 1.43E+06 - - - -1.5612 - 1.924 0.311 - 334 1 2 0 -0.0018 10 0 0 0 9.28E+07 7.84E+07 - - - 3.1641 0.9921 221125_WJC_METTL3_EV_vs_WT_F02.19413.19413.2 2.09E-05 30-Dec R.EALATLK[136.11]PQAGLIVPQ.A "sp|Q9UMS4|PRP19_HUMAN,tr|F5GY56|F5GY56_HUMAN,tr|F5H2I0|F5H2I0_HUMAN" 3 1655.9702 1.28 18554 19413 2 1655.96977 828.9924 Pre-mRNA-processing factor 19 OS=Homo sapiens OX=9606 GN=PRPF19 PE=1 SV=1 6.1 3412.6 - 1.22E+06 - - - -0.2337 - 2.352 0.481 - 210.2 1 1 0 -0.0004 16 0 0 0 2.11E+07 1.65E+07 - - - 4.6963 0.9998 221125_WJC_METTL3_EV_vs_WT_F02.19414.19414.2 0.0137 13/24 R.LINNNPEIFGPLK.R sp|Q9NW13|RBM28_HUMAN 1 1467.8086 0.5 18555 19414 2 1467.806337 734.9116 RNA-binding protein 28 OS=Homo sapiens OX=9606 GN=RBM28 PE=1 SV=3 6 3412.8 - 668691 - - - -1.5179 - 2.502 0.477 - 589.1 1 2 0 -0.0022 13 0 0 0 1.10E+07 2.18E+07 - - - 4.9172 0.9987 221125_WJC_METTL3_EV_vs_WT_F02.19416.19416.2 0.000732 20-Aug K.FSPAGPILSIR.L "sp|Q9H361|PABP3_HUMAN,sp|Q5JQF8|PAP1M_HUMAN,sp|Q4VXU2|PAP1L_HUMAN,sp|P11940|PABP1_HUMAN,tr|A0A7I2V3J9|A0A7I2V3J9_HUMAN,tr|A0A7I2V649|A0A7I2V649_HUMAN,tr|A0A6Q8JFT6|A0A6Q8JFT6_HUMAN,tr|E5RHG7|E5RHG7_HUMAN,tr|E5RFD8|E5RFD8_HUMAN,tr|H0YAR2|H0YAR2_HUMAN,tr|E7ERJ7|E7ERJ7_HUMAN,tr|E5RJB9|E5RJB9_HUMAN,tr|A0A7I2YQ88|A0A7I2YQ88_HUMAN,tr|E5RGC4|E5RGC4_HUMAN,tr|E5RH24|E5RH24_HUMAN,tr|H0YBN4|H0YBN4_HUMAN,tr|A0A087WTT1|A0A087WTT1_HUMAN,tr|A0A7I2YQ90|A0A7I2YQ90_HUMAN,tr|A0A6Q8JFV4|A0A6Q8JFV4_HUMAN" 19 1156.6604 1.62 18556 19416 2 1156.65909 579.3375 Polyadenylate-binding protein 3 OS=Homo sapiens OX=9606 GN=PABPC3 PE=1 SV=2 9.75 3413 - 2.23E+07 - - - -1.1706 - 1.692 0.262 - 241.8 1 2 0 -0.0014 11 0 0 0 7.60E+08 4.70E+08 - - - 2.3984 0.9999 221125_WJC_METTL3_EV_vs_WT_F02.19418.19418.3 0.000376 16/56 R.MATEVAADALGEEWK.G "sp|P62753|RS6_HUMAN,tr|A2A3R5|A2A3R5_HUMAN,tr|A2A3R7|A2A3R7_HUMAN" 3 1619.7501 1.32 18557 19418 3 1619.749476 540.924 40S ribosomal protein S6 OS=Homo sapiens OX=9606 GN=RPS6 PE=1 SV=1 4 3413.2 - 8.08E+06 - - - -0.3994 - 2.485 0.447 - 335.2 1 2 0 -0.0006 15 0 0 0 8.75E+07 6.63E+07 - - - 5.8987 1 221125_WJC_METTL3_EV_vs_WT_F02.19419.19419.3 0.000377 Dec-56 R.YINENLIVNTDELGR.D "sp|P17987|TCPA_HUMAN,tr|F5H136|F5H136_HUMAN,tr|F5H7Y1|F5H7Y1_HUMAN,tr|E7ERF2|E7ERF2_HUMAN" 4 1761.8897 0.41 18558 19419 3 1761.889252 588.3039 T-complex protein 1 subunit alpha OS=Homo sapiens OX=9606 GN=TCP1 PE=1 SV=1 4.14 3413.2 - 7.45E+06 - - - -0.2702 - 2.51 0.531 - 201.5 1 2 0 -0.0005 15 0 0 0 7.87E+07 1.91E+08 - - - 6.8613 1 221125_WJC_METTL3_EV_vs_WT_F02.19420.19420.3 1.74E-06 17/64 R.AIVAIENPADVSVISSR.N "sp|P08865|RSSA_HUMAN,tr|C9J9K3|C9J9K3_HUMAN,tr|A0A0C4DG17|A0A0C4DG17_HUMAN,tr|F8WD59|F8WD59_HUMAN" 4 1739.9418 0.96 18559 19420 3 1739.942231 580.9879 40S ribosomal protein SA OS=Homo sapiens OX=9606 GN=RPSA PE=1 SV=4 4.37 3413.3 - 4.36E+06 - - - 0.2684 - 3.046 0.506 - 488.4 1 2 0 0.0005 17 0 0 0 8.22E+07 8.60E+07 - - - 6.9951 0.9862 221125_WJC_METTL3_EV_vs_WT_F02.19421.19421.2 0.241 13/24 K.ALEQLNGFELAGR.P "sp|Q14498|RBM39_HUMAN,sp|Q86U06|RBM23_HUMAN,tr|A0A0U1RQW2|A0A0U1RQW2_HUMAN,tr|H0Y4X3|H0Y4X3_HUMAN,tr|H0YJJ3|H0YJJ3_HUMAN,tr|G3XAP0|G3XAP0_HUMAN,tr|A0A0U1RQH7|A0A0U1RQH7_HUMAN,tr|G3V5Z6|G3V5Z6_HUMAN,tr|G3XAC6|G3XAC6_HUMAN" 9 1416.7361 0.29 18560 19421 2 1416.737496 709.3753 RNA-binding protein 39 OS=Homo sapiens OX=9606 GN=RBM39 PE=1 SV=2 4.53 3413.4 - 2.21E+06 - - - 0.9656 - 2.868 0.338 - 624.9 1 1 0 0.0014 13 0 0 0 6.23E+07 2.16E+08 - - - 4.2412 0.9996 221125_WJC_METTL3_EV_vs_WT_F02.19422.19422.2 4.39E-07 20-Oct M.VDYYEVLGVQR.H "sp|O75190|DNJB6_HUMAN,tr|C9JDX6|C9JDX6_HUMAN,tr|C9JN01|C9JN01_HUMAN,tr|E9PH18|E9PH18_HUMAN,tr|A0A0J9YX62|A0A0J9YX62_HUMAN,tr|C9JB42|C9JB42_HUMAN,tr|C9JDR7|C9JDR7_HUMAN,tr|C9J2P2|C9J2P2_HUMAN,tr|C9J2C4|C9J2C4_HUMAN,tr|F8WCZ4|F8WCZ4_HUMAN" 10 1339.6772 1.28 18561 19422 2 1339.673243 670.8459 DnaJ homolog subfamily B member 6 OS=Homo sapiens OX=9606 GN=DNAJB6 PE=1 SV=2 4.37 3413.4 - 2.17E+06 - - - -2.9656 - 2.068 0.576 - 313.6 1 2 0 -0.004 11 0 0 0 6.18E+07 4.83E+07 - - - 5.2597 1 221125_WJC_METTL3_EV_vs_WT_F02.19424.19424.2 2.62E-07 13/20 M.VDYYEVLGVQR[166.11].H "sp|O75190|DNJB6_HUMAN,tr|C9JDX6|C9JDX6_HUMAN,tr|C9JN01|C9JN01_HUMAN,tr|E9PH18|E9PH18_HUMAN,tr|A0A0J9YX62|A0A0J9YX62_HUMAN,tr|C9JB42|C9JB42_HUMAN,tr|C9JDR7|C9JDR7_HUMAN,tr|C9J2P2|C9J2P2_HUMAN,tr|C9J2C4|C9J2C4_HUMAN,tr|F8WCZ4|F8WCZ4_HUMAN" 10 1349.6855 1.28 18563 19424 2 1349.682848 675.85 DnaJ homolog subfamily B member 6 OS=Homo sapiens OX=9606 GN=DNAJB6 PE=1 SV=2 4.37 3413.6 - 1.45E+06 - - - -1.9545 - 2.338 0.631 - 580.4 1 2 0 -0.0026 11 0 0 0 6.18E+07 4.83E+07 - - - 5.9983 0.9998 221125_WJC_METTL3_EV_vs_WT_F02.19426.19426.2 0.00101 24-Sep R.DVFLNGSYNDYVR.E "sp|Q96MU7|YTDC1_HUMAN,tr|J3QR07|J3QR07_HUMAN,tr|J3KRG5|J3KRG5_HUMAN" 3 1560.7209 1.08 18565 19426 2 1560.718255 781.3677 YTH domain-containing protein 1 OS=Homo sapiens OX=9606 GN=YTHDC1 PE=1 SV=3 4.21 3413.8 - 1.13E+06 - - - -1.6768 - 2.021 0.517 - 186.3 1 2 0 -0.0026 13 0 0 0 1.10E+07 1.02E+07 - - - 4.6645 0.9999 221125_WJC_METTL3_EV_vs_WT_F02.19427.19427.2 0.000392 26-Dec K.ITSQIFIGPTYYQR[166.11].L "sp|P30876|RPB2_HUMAN,tr|C9J4M6|C9J4M6_HUMAN,tr|C9J2Y9|C9J2Y9_HUMAN" 3 1695.886 1 18566 19427 2 1695.88431 848.9503 DNA-directed RNA polymerase II subunit RPB2 OS=Homo sapiens OX=9606 GN=POLR2B PE=1 SV=1 8.59 3414 - 928371 - - - -0.983 - 2.384 0.504 - 347.2 1 2 0 -0.0017 14 0 0 0 1.03E+07 1.04E+07 - - - 4.9432 0.9726 221125_WJC_METTL3_EV_vs_WT_F02.19429.19429.2 6.13E-05 18-Dec K.TGFFEFQAAK.D "sp|Q9P2J5|SYLC_HUMAN,tr|A0A6I8PIV1|A0A6I8PIV1_HUMAN,tr|A0A6I8PRS0|A0A6I8PRS0_HUMAN,tr|A0A6I8PLB8|A0A6I8PLB8_HUMAN,tr|A0A6I8PIT3|A0A6I8PIT3_HUMAN,tr|A0A6I8PLB3|A0A6I8PLB3_HUMAN,tr|A0A6I8PS05|A0A6I8PS05_HUMAN,tr|B4DER1|B4DER1_HUMAN,tr|A0A6I8PL42|A0A6I8PL42_HUMAN" 9 1144.5553 1.01 18568 19429 2 1144.545726 573.2849 "Leucine--tRNA ligase, cytoplasmic OS=Homo sapiens OX=9606 GN=LARS1 PE=1 SV=2" 5.66 3414.2 - 857932 - - - -8.3736 - 1.762 0.478 - 330.9 1 2 0 -0.0096 10 0 0 0 2.84E+07 2.81E+07 - - - 4.1496 0.9999 221125_WJC_METTL3_EV_vs_WT_F02.19431.19431.2 4.25E-06 13/26 K.ITSQIFIGPTYYQR.L "sp|P30876|RPB2_HUMAN,tr|C9J4M6|C9J4M6_HUMAN,tr|C9J2Y9|C9J2Y9_HUMAN" 3 1685.8777 1 18570 19431 2 1685.879335 843.9461 DNA-directed RNA polymerase II subunit RPB2 OS=Homo sapiens OX=9606 GN=POLR2B PE=1 SV=1 8.59 3414.4 - 822612 - - - 0.9657 - 2.891 0.53 - 470.4 1 2 0 0.0016 14 0 0 0 1.03E+07 1.04E+07 - - - 5.6191 0.9992 221125_WJC_METTL3_EV_vs_WT_F02.19434.19434.2 2.52E-05 22-Dec R.ILNMDFETEVDK.L "sp|Q9H0S4|DDX47_HUMAN,tr|F5H1N9|F5H1N9_HUMAN" 2 1452.6806 0.95 18573 19434 2 1452.674794 727.3476 Probable ATP-dependent RNA helicase DDX47 OS=Homo sapiens OX=9606 GN=DDX47 PE=1 SV=1 3.92 3414.8 - 653850 - - - -4.0291 - 2.622 0.529 - 470.7 1 2 0 -0.0059 12 0 0 0 1.38E+07 1.46E+07 - - - 5.4826 1 221125_WJC_METTL3_EV_vs_WT_F02.19439.19439.3 0.147 15/64 R.AIVAIENPADVSVISSR[166.11].N "sp|P08865|RSSA_HUMAN,tr|C9J9K3|C9J9K3_HUMAN,tr|A0A0C4DG17|A0A0C4DG17_HUMAN,tr|F8WD59|F8WD59_HUMAN" 4 1749.95 0.96 18576 19439 3 1749.950976 584.324 40S ribosomal protein SA OS=Homo sapiens OX=9606 GN=RPSA PE=1 SV=4 4.37 3415.4 - 6.01E+06 - - - 0.5383 - 2.62 0.446 - 316.3 1 2 0 0.0009 17 0 0 0 8.22E+07 8.60E+07 - - - 5.9455 0.9995 221125_WJC_METTL3_EV_vs_WT_F02.19440.19440.2 0.0156 18-Aug K.AISSDMFFGR.E "sp|Q8N6H7|ARFG2_HUMAN,tr|E9PMU9|E9PMU9_HUMAN,tr|H0YDN9|H0YDN9_HUMAN,tr|G5E9L0|G5E9L0_HUMAN,tr|A0A0D9SF70|A0A0D9SF70_HUMAN" 5 1129.5226 1.18 18577 19440 2 1129.522781 565.7686 ADP-ribosylation factor GTPase-activating protein 2 OS=Homo sapiens OX=9606 GN=ARFGAP2 PE=1 SV=1 5.88 3415.5 - 5.09E+06 - - - 0.1337 - 1.823 0.326 - 188.9 1 2 0 0.0002 10 0 0 0 9.27E+07 7.85E+07 - - - 3.1249 0.9937 221125_WJC_METTL3_EV_vs_WT_F02.19441.19441.2 1.93E-05 24-Sep K.WGDAGAEYVVEST.G "sp|P04406|G3P_HUMAN,tr|E7EUT5|E7EUT5_HUMAN" 2 1382.599 - 18578 19441 2 1382.598908 692.3068 Glyceraldehyde-3-phosphate dehydrogenase OS=Homo sapiens OX=9606 GN=GAPDH PE=1 SV=3 3.57 3415.5 - 3.05E+06 - - - -0.0853 - 2.266 0.534 - 255.2 1 1 0 -0.0001 13 0 0 0 - - - - - 5.0845 0.9998 221125_WJC_METTL3_EV_vs_WT_F02.19442.19442.2 0.0404 16-Nov R.NALSSLWGK[136.11].L "sp|P60228|EIF3E_HUMAN,tr|A0A7I2V3I2|A0A7I2V3I2_HUMAN,tr|H0YBP5|H0YBP5_HUMAN,tr|A0A7I2V5Z6|A0A7I2V5Z6_HUMAN,tr|A0A7I2V2H9|A0A7I2V2H9_HUMAN,tr|B3KW56|B3KW56_HUMAN,tr|A0A7I2V4B4|A0A7I2V4B4_HUMAN,tr|E5RGA2|E5RGA2_HUMAN,tr|A0A7I2V3I0|A0A7I2V3I0_HUMAN,tr|A0A7I2V3S3|A0A7I2V3S3_HUMAN,tr|A0A7I2V4G3|A0A7I2V4G3_HUMAN,tr|E5RHS5|E5RHS5_HUMAN,tr|A0A7I2V2W0|A0A7I2V2W0_HUMAN,tr|A0A7I2V5P9|A0A7I2V5P9_HUMAN" 14 982.5327 1.1 18579 19442 2 982.532326 492.2736 Eukaryotic translation initiation factor 3 subunit E OS=Homo sapiens OX=9606 GN=EIF3E PE=1 SV=1 8.75 3415.6 - 2.64E+06 - - - -0.4122 - 2.175 0.353 - 473.5 1 2 0 -0.0004 9 0 0 0 5.60E+07 5.10E+07 - - - 3.8961 0.9997 221125_WJC_METTL3_EV_vs_WT_F02.19444.19444.2 1.45E-05 22-Oct R.ILNMDFETEVDK[136.11].L "sp|Q9H0S4|DDX47_HUMAN,tr|F5H1N9|F5H1N9_HUMAN" 2 1460.6948 0.95 18581 19444 2 1460.691599 731.3547 Probable ATP-dependent RNA helicase DDX47 OS=Homo sapiens OX=9606 GN=DDX47 PE=1 SV=1 3.92 3415.7 - 1.30E+06 - - - -2.2236 - 1.985 0.525 - 215.7 1 2 0 -0.0032 12 0 0 0 1.38E+07 1.46E+07 - - - 4.7216 0.923 221125_WJC_METTL3_EV_vs_WT_F02.19445.19445.3 0.0137 Oct-48 K.ALEQLNGFELAGR.P "sp|Q14498|RBM39_HUMAN,sp|Q86U06|RBM23_HUMAN,tr|A0A0U1RQW2|A0A0U1RQW2_HUMAN,tr|H0Y4X3|H0Y4X3_HUMAN,tr|H0YJJ3|H0YJJ3_HUMAN,tr|G3XAP0|G3XAP0_HUMAN,tr|A0A0U1RQH7|A0A0U1RQH7_HUMAN,tr|G3V5Z6|G3V5Z6_HUMAN,tr|G3XAC6|G3XAC6_HUMAN" 9 1416.7361 1.36 18582 19445 3 1416.736946 473.2527 RNA-binding protein 39 OS=Homo sapiens OX=9606 GN=RBM39 PE=1 SV=2 4.53 3415.8 - 655362 - - - 0.5774 - 1.915 0.285 - 93.4 1 1 0 0.0008 13 0 0 0 5.90E+06 4.33E+06 - - - 3.4788 1 221125_WJC_METTL3_EV_vs_WT_F02.19446.19446.3 5.76E-09 13/40 M.VDYYEVLGVQR.H "sp|O75190|DNJB6_HUMAN,tr|C9JDX6|C9JDX6_HUMAN,tr|C9JN01|C9JN01_HUMAN,tr|E9PH18|E9PH18_HUMAN,tr|A0A0J9YX62|A0A0J9YX62_HUMAN,tr|C9JB42|C9JB42_HUMAN,tr|C9JDR7|C9JDR7_HUMAN,tr|C9J2P2|C9J2P2_HUMAN,tr|C9J2C4|C9J2C4_HUMAN,tr|F8WCZ4|F8WCZ4_HUMAN" 10 1339.6772 1.36 18583 19446 3 1339.675379 447.5663 DnaJ homolog subfamily B member 6 OS=Homo sapiens OX=9606 GN=DNAJB6 PE=1 SV=2 4.37 3416 - 550220 - - - -1.3712 - 2.425 0.496 - 262.9 1 2 0 -0.0018 11 0 0 0 1.14E+07 8.39E+06 - - - 6.5859 0.9999 221125_WJC_METTL3_EV_vs_WT_F02.19450.19450.2 4.43E-05 20-Nov R.ADLEMQIESLK.E sp|P02533|K1C14_HUMAN 1 1275.6381 1528.24 18585 19450 2 1275.638378 638.8263 "Keratin, type I cytoskeletal 14 OS=Homo sapiens OX=9606 GN=KRT14 PE=1 SV=4" 4.14 3416.5 - 1.03E+07 - - - 0.254 - 2.495 0.468 - 688.2 1 2 0 0.0003 11 0 0 0 1.93E+08 1.27E+05 - - - 4.9709 0.9994 221125_WJC_METTL3_EV_vs_WT_F02.19451.19451.2 0.192 16-Sep R.NALSSLWGK.L "sp|P60228|EIF3E_HUMAN,tr|A0A7I2V3I2|A0A7I2V3I2_HUMAN,tr|H0YBP5|H0YBP5_HUMAN,tr|A0A7I2V5Z6|A0A7I2V5Z6_HUMAN,tr|A0A7I2V2H9|A0A7I2V2H9_HUMAN,tr|B3KW56|B3KW56_HUMAN,tr|A0A7I2V4B4|A0A7I2V4B4_HUMAN,tr|E5RGA2|E5RGA2_HUMAN,tr|A0A7I2V3I0|A0A7I2V3I0_HUMAN,tr|A0A7I2V3S3|A0A7I2V3S3_HUMAN,tr|A0A7I2V4G3|A0A7I2V4G3_HUMAN,tr|E5RHS5|E5RHS5_HUMAN,tr|A0A7I2V2W0|A0A7I2V2W0_HUMAN,tr|A0A7I2V5P9|A0A7I2V5P9_HUMAN" 14 974.5185 1.1 18586 19451 2 974.519924 488.2665 Eukaryotic translation initiation factor 3 subunit E OS=Homo sapiens OX=9606 GN=EIF3E PE=1 SV=1 8.75 3416.6 - 3.90E+06 - - - 1.4294 - 1.95 0.333 - 276.7 1 2 0 0.0014 9 0 0 0 5.60E+07 5.10E+07 - - - 3.4322 1 221125_WJC_METTL3_EV_vs_WT_F02.19452.19452.3 0.000166 13/52 K.EDIYAVEIVGGATR[166.11].L "sp|P34932|HSP74_HUMAN,tr|A0A087WTS8|A0A087WTS8_HUMAN,tr|A0A087WYC1|A0A087WYC1_HUMAN" 3 1501.7652 0.1 18587 19452 3 1501.767011 501.5957 Heat shock 70 kDa protein 4 OS=Homo sapiens OX=9606 GN=HSPA4 PE=1 SV=4 4.14 3416.6 - 2.02E+06 - - - 1.2106 - 2.495 0.477 - 171.7 1 2 0 0.0018 14 0 0 0 5.08E+06 5.30E+07 - - - 6.2873 0.9891 221125_WJC_METTL3_EV_vs_WT_F02.19453.19453.2 0.00182 24-Dec N.SLATAGDGLIELR.K "sp|P35232|PHB_HUMAN,tr|C9JZ20|C9JZ20_HUMAN,tr|C9JW96|C9JW96_HUMAN" 3 1314.7143 0.96 18588 19453 2 1314.715288 658.3644 Prohibitin OS=Homo sapiens OX=9606 GN=PHB PE=1 SV=1 4.37 3416.7 - 1.64E+06 - - - 0.7287 - 2.231 0.452 - 369.4 1 1 0 0.001 13 0 0 0 2.23E+07 2.31E+07 - - - 4.4387 0.9999 221125_WJC_METTL3_EV_vs_WT_F02.19456.19456.2 0.0636 13/24 K.LLLTAQQMLQDSK.T "sp|Q16512|PKN1_HUMAN,tr|K7EKY9|K7EKY9_HUMAN,tr|K7EM57|K7EM57_HUMAN" 3 1487.8018 2.79 18591 19456 2 1487.801467 744.9082 Serine\threonine-protein kinase N1 OS=Homo sapiens OX=9606 GN=PKN1 PE=1 SV=2 5.84 3416.9 - 775669 - - - -0.2003 - 2.516 0.488 - 531.8 1 2 0 -0.0003 13 0 0 0 2.30E+07 8.25E+06 - - - 5.0133 0.9941 221125_WJC_METTL3_EV_vs_WT_F02.19458.19458.2 0.00254 15/18 N.PEAALSPTFR[166.11].S "sp|Q86U44|MTA70_HUMAN,tr|B4E349|B4E349_HUMAN,tr|F5H6D8|F5H6D8_HUMAN,tr|B4DTN4|B4DTN4_HUMAN" 4 1097.5745 0.22 18593 19458 2 1097.574848 549.7945 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 6.43 3417.2 - 730258 - - - 0.3362 - 2.68 0.48 - 1076.9 1 1 0 0.0004 10 0 0 0 8.47E+06 3.86E+07 - - - 5.3379 0.9983 221125_WJC_METTL3_EV_vs_WT_F02.19459.19459.2 0.00185 14/24 K.LLLTAQQMLQDSK[136.11].T "sp|Q16512|PKN1_HUMAN,tr|K7EKY9|K7EKY9_HUMAN,tr|K7EM57|K7EM57_HUMAN" 3 1495.816 2.79 18594 19459 2 1495.811314 748.9153 Serine\threonine-protein kinase N1 OS=Homo sapiens OX=9606 GN=PKN1 PE=1 SV=2 5.84 3417.3 - 718366 - - - -3.1093 - 2.523 0.265 - 578.4 1 2 0 -0.0047 13 0 0 0 2.30E+07 8.25E+06 - - - 3.372 1 221125_WJC_METTL3_EV_vs_WT_F02.19462.19462.2 5.49E-09 24-Dec R.DVFLNGSYNDYVR[166.11].E "sp|Q96MU7|YTDC1_HUMAN,tr|J3QR07|J3QR07_HUMAN,tr|J3KRG5|J3KRG5_HUMAN" 3 1570.7291 1.08 18596 19462 2 1570.733741 786.3718 YTH domain-containing protein 1 OS=Homo sapiens OX=9606 GN=YTHDC1 PE=1 SV=3 4.21 3417.7 - 507309 - - - 2.9279 - 2.587 0.611 - 458.5 1 2 0 0.0046 13 0 0 0 1.10E+07 1.02E+07 - - - 5.9919 0.9999 221125_WJC_METTL3_EV_vs_WT_F02.19465.19465.2 0.0663 16/30 R.ELLYGGTSPTAETILK[136.11].N "sp|O95793|STAU1_HUMAN,tr|Q5JW30|Q5JW30_HUMAN" 2 1699.9124 1.85 18598 19465 2 1699.913685 850.9635 Double-stranded RNA-binding protein Staufen homolog 1 OS=Homo sapiens OX=9606 GN=STAU1 PE=1 SV=2 4.53 3418 - 1.81E+06 - - - 0.7747 - 3.003 0.518 - 578 1 2 0 0.0013 16 0 0 0 2.33E+08 1.26E+08 - - - 5.57 1 221125_WJC_METTL3_EV_vs_WT_F02.19467.19467.2 1.43E-07 16/30 R.ELLYGGTSPTAETILK.N "sp|O95793|STAU1_HUMAN,tr|Q5JW30|Q5JW30_HUMAN" 2 1691.8982 1.85 18600 19467 2 1691.899695 846.9564 Double-stranded RNA-binding protein Staufen homolog 1 OS=Homo sapiens OX=9606 GN=STAU1 PE=1 SV=2 4.53 3418.1 - 2.72E+06 - - - 0.9025 - 2.944 0.61 - 657.4 1 2 0 0.0015 16 0 0 0 2.33E+08 1.26E+08 - - - 6.2006 0.9998 221125_WJC_METTL3_EV_vs_WT_F02.19469.19469.2 0.000379 16-Oct K.AAIDWFDGK.E "sp|P35637|FUS_HUMAN,sp|Q92804|RBP56_HUMAN,tr|H3BPE7|H3BPE7_HUMAN,tr|A0A075B7D9|A0A075B7D9_HUMAN" 4 1021.4869 1.28 18602 19469 2 1021.487604 511.7507 RNA-binding protein FUS OS=Homo sapiens OX=9606 GN=FUS PE=1 SV=1 4.21 3418.4 - 792244 - - - 0.6931 - 1.85 0.43 - 208 1 2 0 0.0007 9 0 0 0 2.09E+07 1.63E+07 - - - 3.9965 0.9999 221125_WJC_METTL3_EV_vs_WT_F02.19470.19470.2 6.85E-06 15/30 K.VPPAVIIPPAAPLSGR.R "sp|Q9H4A3|WNK1_HUMAN,tr|F5GWT4|F5GWT4_HUMAN,tr|A0A6Q8PFM0|A0A6Q8PFM0_HUMAN" 3 1553.9293 2 18603 19470 2 1553.929276 777.972 Serine\threonine-protein kinase WNK1 OS=Homo sapiens OX=9606 GN=WNK1 PE=1 SV=2 9.72 3418.5 - 766812 - - - -0.047 - 2.657 0.414 - 540 1 2 0 -0.0001 16 0 0 0 1.59E+07 7.97E+06 - - - 4.5013 0.9624 221125_WJC_METTL3_EV_vs_WT_F02.19471.19471.2 0.27 16-Jun K.MIFDVESMK[136.11].K sp|P09874|PARP1_HUMAN 1 1106.5232 1.08 18604 19471 2 1106.526473 554.2689 Poly [ADP-ribose] polymerase 1 OS=Homo sapiens OX=9606 GN=PARP1 PE=1 SV=4 4.37 3418.6 - 490114 - - - 2.9995 - 1.206 0.185 - 69.3 3 2 0 0.0033 9 0 0 0 9.15E+06 8.48E+06 - - - 0.7351 0.9994 221125_WJC_METTL3_EV_vs_WT_F02.19472.19472.2 0.000255 28-Oct R.APEEELPPLDPEEIR.K "sp|Q8IY67|RAVR1_HUMAN,tr|K7EKR9|K7EKR9_HUMAN,tr|E9PAU2|E9PAU2_HUMAN,tr|A0A087WZ13|A0A087WZ13_HUMAN" 4 1732.8519 2.63 18605 19472 2 1732.855395 867.4332 Ribonucleoprotein PTB-binding 1 OS=Homo sapiens OX=9606 GN=RAVER1 PE=1 SV=1 3.83 3418.8 - 280158 - - - 1.9904 - 1.804 0.439 - 238.5 1 2 0 0.0034 15 0 0 0 8.07E+06 3.07E+06 - - - 3.7329 0.9993 221125_WJC_METTL3_EV_vs_WT_F02.19475.19475.2 3.72E-05 20-Sep R.EGQIEPSFVFR.T sp|O00443|P3C2A_HUMAN 1 1307.651 1.6 18606 19475 2 1307.652017 654.8328 Phosphatidylinositol 4-phosphate 3-kinase C2 domain-containing subunit alpha OS=Homo sapiens OX=9606 GN=PIK3C2A PE=1 SV=2 4.53 3419.2 - 2.44E+06 - - - 0.777 - 1.865 0.289 - 242.5 1 2 0 0.001 11 0 0 0 4.42E+07 2.76E+07 - - - 2.8613 0.9999 221125_WJC_METTL3_EV_vs_WT_F02.19476.19476.2 1.19E-06 20-Oct R.WTEYGLTFTEK.W "sp|P21796|VDAC1_HUMAN,tr|C9JI87|C9JI87_HUMAN" 2 1373.6503 1.25 18607 19476 2 1373.648879 687.8324 Voltage-dependent anion-selective channel protein 1 OS=Homo sapiens OX=9606 GN=VDAC1 PE=1 SV=2 4.53 3419.2 - 2.95E+06 - - - -1.0585 - 1.971 0.589 - 285.2 1 2 0 -0.0015 11 0 0 0 1.81E+08 1.45E+08 - - - 5.2265 0.9999 221125_WJC_METTL3_EV_vs_WT_F02.19478.19478.2 0.00169 16/26 R.ALNIVDQEGSLLGK[136.11].G "sp|Q8IX01|SUGP2_HUMAN,tr|M0R2Z9|M0R2Z9_HUMAN,tr|M0R3F6|M0R3F6_HUMAN" 3 1463.8075 0.38 18609 19478 2 1463.808579 732.911 SURP and G-patch domain-containing protein 2 OS=Homo sapiens OX=9606 GN=SUGP2 PE=1 SV=2 4.37 3419.4 - 1.71E+06 - - - 0.731 - 3.084 0.46 - 880 1 2 0 0.0011 14 0 0 0 1.06E+07 2.78E+07 - - - 5.2644 0.9998 221125_WJC_METTL3_EV_vs_WT_F02.19481.19481.2 0.00345 16-Oct R.LIDFLESGK.T "sp|Q92841|DDX17_HUMAN,tr|A0A5H1ZRQ2|A0A5H1ZRQ2_HUMAN,tr|A0A1X7SBZ2|A0A1X7SBZ2_HUMAN" 3 1020.5492 0.93 18612 19481 2 1020.550074 511.2819 Probable ATP-dependent RNA helicase DDX17 OS=Homo sapiens OX=9606 GN=DDX17 PE=1 SV=2 4.37 3419.6 - 866062 - - - 0.8936 - 1.894 0.445 - 237.1 1 2 0 0.0009 9 0 0 0 7.38E+07 7.94E+07 - - - 4.1753 0.9998 221125_WJC_METTL3_EV_vs_WT_F02.19482.19482.3 0.00181 Dec-40 M.VDYYEVLGVQR[166.11].H "sp|O75190|DNJB6_HUMAN,tr|C9JDX6|C9JDX6_HUMAN,tr|C9JN01|C9JN01_HUMAN,tr|E9PH18|E9PH18_HUMAN,tr|A0A0J9YX62|A0A0J9YX62_HUMAN,tr|C9JB42|C9JB42_HUMAN,tr|C9JDR7|C9JDR7_HUMAN,tr|C9J2P2|C9J2P2_HUMAN,tr|C9J2C4|C9J2C4_HUMAN,tr|F8WCZ4|F8WCZ4_HUMAN" 10 1349.6855 1.36 18613 19482 3 1349.685856 450.9024 DnaJ homolog subfamily B member 6 OS=Homo sapiens OX=9606 GN=DNAJB6 PE=1 SV=2 4.37 3419.8 - 603521 - - - 0.2741 - 2.145 0.335 - 231.7 1 2 0 0.0004 11 0 0 0 1.14E+07 8.39E+06 - - - 4.4428 0.9991 221125_WJC_METTL3_EV_vs_WT_F02.19483.19483.2 0.00841 18-Nov K.SSLALGLELR.A sp|Q8TAP8|PPR35_HUMAN 1 1057.6132 1.85 18614 19483 2 1057.614434 529.8139 Protein phosphatase 1 regulatory subunit 35 OS=Homo sapiens OX=9606 GN=PPP1R35 PE=1 SV=1 5.72 3419.9 - 386948 - - - 1.2055 - 1.557 0.348 - 120.1 1 2 0 0.0013 10 0 0 0 3.97E+06 2.15E+06 - - - 2.8468 0.9994 221125_WJC_METTL3_EV_vs_WT_F02.19484.19484.2 0.00379 28-Sep R.AYVAVDGIPQGVLER.N "sp|P16278|BGAL_HUMAN,tr|E7EQ29|E7EQ29_HUMAN" 2 1585.8464 2.19 18615 19484 2 1585.843248 793.9305 Beta-galactosidase OS=Homo sapiens OX=9606 GN=GLB1 PE=1 SV=2 4.37 3420 - 348428 - - - -1.992 - 1.883 0.416 - 171 1 2 0 -0.0032 15 0 0 0 1.28E+06 5.85E+05 - - - 3.6685 1 221125_WJC_METTL3_EV_vs_WT_F02.19485.19485.2 4.06E-09 30-Nov R.IMYDLTSK[136.11]PPGTTEWE.- sp|P49915|GUAA_HUMAN 1 1874.8852 0.82 18616 19485 2 1874.885012 938.4499 GMP synthase [glutamine-hydrolyzing] OS=Homo sapiens OX=9606 GN=GMPS PE=1 SV=1 4.43 3420.2 - 321288 - - - -0.0827 - 2.431 0.65 - 247.3 1 2 0 -0.0002 16 0 0 0 5.81E+06 7.08E+06 - - - 6.0258 0.9995 221125_WJC_METTL3_EV_vs_WT_F02.19489.19489.2 0.0134 16-Sep R.LIDFLESGK[136.11].T "sp|Q92841|DDX17_HUMAN,tr|A0A5H1ZRQ2|A0A5H1ZRQ2_HUMAN,tr|A0A1X7SBZ2|A0A1X7SBZ2_HUMAN" 3 1028.5634 0.92 18618 19489 2 1028.563515 515.289 Probable ATP-dependent RNA helicase DDX17 OS=Homo sapiens OX=9606 GN=DDX17 PE=1 SV=2 4.37 3420.7 - 3.23E+06 - - - 0.1488 - 1.712 0.331 - 155.3 1 2 0 0.0002 9 0 0 0 7.38E+07 7.99E+07 - - - 3.0412 0.9999 221125_WJC_METTL3_EV_vs_WT_F02.19490.19490.2 1.55E-06 14/24 K.LQIWDTAGQESFR[166.11].S "sp|P61019|RAB2A_HUMAN,sp|Q8WUD1|RAB2B_HUMAN,tr|A0A3B3ITL1|A0A3B3ITL1_HUMAN,tr|E9PKL7|E9PKL7_HUMAN" 4 1559.7608 1.05 18619 19490 2 1559.760118 780.8877 Ras-related protein Rab-2A OS=Homo sapiens OX=9606 GN=RAB2A PE=1 SV=1 4.37 3420.9 - 1.64E+06 - - - -0.4219 - 2.838 0.514 - 596.2 1 2 0 -0.0007 13 0 0 0 4.11E+07 3.93E+07 - - - 5.5143 0.9847 221125_WJC_METTL3_EV_vs_WT_F02.19491.19491.2 0.000109 13/26 R.ALNIVDQEGSLLGK.G "sp|Q8IX01|SUGP2_HUMAN,tr|M0R2Z9|M0R2Z9_HUMAN,tr|M0R3F6|M0R3F6_HUMAN" 3 1455.7933 0.36 18620 19491 2 1455.80605 728.9039 SURP and G-patch domain-containing protein 2 OS=Homo sapiens OX=9606 GN=SUGP2 PE=1 SV=2 4.37 3420.9 - 1.97E+06 - - - 8.7519 - 2.376 0.489 - 520.7 1 2 0 0.0127 14 0 0 0 1.06E+07 2.91E+07 - - - 4.8205 1 221125_WJC_METTL3_EV_vs_WT_F02.19493.19493.2 6.34E-06 13/24 K.LQIWDTAGQESFR.S "sp|P61019|RAB2A_HUMAN,sp|Q8WUD1|RAB2B_HUMAN,tr|A0A3B3ITL1|A0A3B3ITL1_HUMAN,tr|E9PKL7|E9PKL7_HUMAN" 4 1549.7525 1.04 18622 19493 2 1549.750645 775.8835 Ras-related protein Rab-2A OS=Homo sapiens OX=9606 GN=RAB2A PE=1 SV=1 4.37 3421.1 - 1.79E+06 - - - -1.2008 - 2.87 0.545 - 488.8 1 2 0 -0.0019 13 0 0 0 4.11E+07 3.94E+07 - - - 5.7717 0.9997 221125_WJC_METTL3_EV_vs_WT_F02.19497.19497.2 0.00617 14-Oct K.WLTLEVC[160.03]R[166.11].E "sp|Q9NR56|MBNL1_HUMAN,sp|Q5VZF2|MBNL2_HUMAN,sp|Q9NUK0|MBNL3_HUMAN,tr|H7C4T5|H7C4T5_HUMAN,tr|A0A0A0MQX8|A0A0A0MQX8_HUMAN,tr|A0A7P0T9I3|A0A7P0T9I3_HUMAN,tr|B1AKI6|B1AKI6_HUMAN,tr|C9JP00|C9JP00_HUMAN,tr|O95205|O95205_HUMAN" 9 1085.5567 1.73 18626 19497 2 1085.557051 543.7856 Muscleblind-like protein 1 OS=Homo sapiens OX=9606 GN=MBNL1 PE=1 SV=2 5.99 3421.5 - 897490 - - - 0.304 - 2.013 0.327 - 406.1 1 2 0 0.0003 8 0 0 0 4.18E+07 2.42E+07 - - - 3.5662 0.9986 221125_WJC_METTL3_EV_vs_WT_F02.19498.19498.2 0.00902 16-Aug R.GAGWLFGAK[136.11].V sp|O00743|PPP6_HUMAN 1 913.4901 0.74 18627 19498 2 913.490848 457.7523 Serine\threonine-protein phosphatase 6 catalytic subunit OS=Homo sapiens OX=9606 GN=PPP6C PE=1 SV=1 8.75 3421.6 - 776029 - - - 0.7772 - 1.456 0.282 - 218.1 1 2 0 0.0007 9 0 0 0 4.62E+06 6.26E+06 - - - 2.2105 0.9944 221125_WJC_METTL3_EV_vs_WT_F02.19501.19501.2 1.37E-05 24-Dec L.LEEAFSQFGPIER[166.11].A sp|P23246|SFPQ_HUMAN 1 1531.7546 0.34 18630 19501 2 1531.754694 766.8846 "Splicing factor, proline- and glutamine-rich OS=Homo sapiens OX=9606 GN=SFPQ PE=1 SV=2" 4.25 3422 - 764012 - - - 0.0431 - 2.653 0.517 - 637 1 1 0 0.0001 13 0 0 0 1.98E+06 5.91E+06 - - - 5.3637 1 221125_WJC_METTL3_EV_vs_WT_F02.19503.19503.2 4.09E-06 22-Dec R.APASEEEFQFLR[166.11].C "sp|P29590|PML_HUMAN,tr|H3BT57|H3BT57_HUMAN" 2 1432.6862 0.86 18631 19503 2 1432.689982 717.3504 Protein PML OS=Homo sapiens OX=9606 GN=PML PE=1 SV=3 4.25 3422.2 - 2.59E+06 - - - 2.6293 - 2.686 0.596 - 617.2 1 2 0 0.0038 12 0 0 0 2.20E+07 2.57E+07 - - - 6.0416 1 221125_WJC_METTL3_EV_vs_WT_F02.19508.19508.2 2.74E-08 14/24 K.TPSSDVLVFDYTK.H "sp|Q09028|RBBP4_HUMAN,sp|Q16576|RBBP7_HUMAN,tr|Q5JP01|Q5JP01_HUMAN,tr|H0YF10|H0YF10_HUMAN,tr|E9PC52|E9PC52_HUMAN" 5 1470.7242 1.47 18635 19508 2 1470.721574 736.3694 Histone-binding protein RBBP4 OS=Homo sapiens OX=9606 GN=RBBP4 PE=1 SV=3 4.21 3422.6 - 2.73E+06 - - - -1.8032 - 3.093 0.551 - 816.9 1 2 0 -0.0027 13 0 0 0 3.34E+08 2.27E+08 - - - 6.0078 1 221125_WJC_METTL3_EV_vs_WT_F02.19509.19509.2 4.42E-09 19/24 K.TPSSDVLVFDYTK[136.11].H "sp|Q09028|RBBP4_HUMAN,sp|Q16576|RBBP7_HUMAN,tr|Q5JP01|Q5JP01_HUMAN,tr|H0YF10|H0YF10_HUMAN,tr|E9PC52|E9PC52_HUMAN" 5 1478.7384 1.47 18636 19509 2 1478.740873 740.3765 Histone-binding protein RBBP4 OS=Homo sapiens OX=9606 GN=RBBP4 PE=1 SV=3 4.21 3422.7 - 2.36E+06 - - - 1.6548 - 3.517 0.659 - 1954.3 1 2 0 0.0024 13 0 0 0 3.34E+08 2.27E+08 - - - 7.1353 0.9999 221125_WJC_METTL3_EV_vs_WT_F02.19510.19510.2 1.97E-06 13/22 R.APASEEEFQFLR.C "sp|P29590|PML_HUMAN,tr|H3BT57|H3BT57_HUMAN" 2 1422.6779 0.26 18637 19510 2 1422.677541 712.3462 Protein PML OS=Homo sapiens OX=9606 GN=PML PE=1 SV=3 4.25 3422.7 - 2.20E+06 - - - -0.284 - 2.447 0.582 - 732.4 1 2 0 -0.0004 12 0 0 0 2.26E+07 8.57E+07 - - - 5.6941 0.9997 221125_WJC_METTL3_EV_vs_WT_F02.19512.19512.2 0.00306 12-Sep R.NDWLDLR[166.11].V "sp|Q6RFH5|WDR74_HUMAN,tr|E9PS41|E9PS41_HUMAN" 2 940.4642 1.25 18639 19512 2 940.463911 471.2394 WD repeat-containing protein 74 OS=Homo sapiens OX=9606 GN=WDR74 PE=1 SV=1 4.21 3422.9 - 865436 - - - -0.3073 - 1.631 0.433 - 377.3 1 2 0 -0.0003 7 0 0 0 7.57E+06 6.06E+06 - - - 3.7891 0.9999 221125_WJC_METTL3_EV_vs_WT_F02.19514.19514.2 4.36E-07 14/30 K.VPPAVIIPPAAPLSGR[166.11].R "sp|Q9H4A3|WNK1_HUMAN,tr|F5GWT4|F5GWT4_HUMAN,tr|A0A6Q8PFM0|A0A6Q8PFM0_HUMAN" 3 1563.9376 2.02 18641 19514 2 1563.936146 782.9761 Serine\threonine-protein kinase WNK1 OS=Homo sapiens OX=9606 GN=WNK1 PE=1 SV=2 9.72 3423.2 - 489676 - - - -0.9419 - 2.604 0.493 - 548.2 1 2 0 -0.0015 16 0 0 0 2.29E+07 1.13E+07 - - - 5.0348 0.97 221125_WJC_METTL3_EV_vs_WT_F02.19515.19515.2 0.874 16-Sep R.HLWSPFGLR[166.11].S "sp|Q13724|MOGS_HUMAN,tr|A0A3B3IRK6|A0A3B3IRK6_HUMAN,tr|A0A3B3IRW2|A0A3B3IRW2_HUMAN" 3 1121.601 0.43 18642 19515 2 1121.5982 561.8078 Mannosyl-oligosaccharide glucosidase OS=Homo sapiens OX=9606 GN=MOGS PE=1 SV=5 9.76 3423.3 - 464816 - - - -2.4688 - 1.368 0.09 - 187.4 1 2 0 -0.0028 9 0 0 0 2.76E+06 6.41E+06 - - - 0.6114 1 221125_WJC_METTL3_EV_vs_WT_F02.19518.19518.2 4.12E-10 14/26 K.EDIYAVEIVGGATR[166.11].L "sp|P34932|HSP74_HUMAN,tr|A0A087WTS8|A0A087WTS8_HUMAN,tr|A0A087WYC1|A0A087WYC1_HUMAN" 3 1501.7652 0.09 18644 19518 2 1501.764655 751.8899 Heat shock 70 kDa protein 4 OS=Homo sapiens OX=9606 GN=HSPA4 PE=1 SV=4 4.14 3423.6 - 4.45E+06 - - - -0.3582 - 2.81 0.67 - 803.5 1 2 0 -0.0005 14 0 0 0 9.47E+06 1.01E+08 - - - 6.5822 0.9999 221125_WJC_METTL3_EV_vs_WT_F02.19521.19521.2 3.40E-06 22-Oct K.EQADFALEALAK.A "sp|Q7Z406|MYH14_HUMAN,sp|P35579|MYH9_HUMAN,tr|M0QY43|M0QY43_HUMAN" 3 1304.6612 0.99 18647 19521 2 1304.661592 653.3379 Myosin-14 OS=Homo sapiens OX=9606 GN=MYH14 PE=1 SV=2 4.14 3423.8 - 3.44E+06 - - - 0.2759 - 1.978 0.506 - 326.4 1 2 0 0.0004 12 0 0 0 9.15E+07 9.26E+07 - - - 4.5729 1 221125_WJC_METTL3_EV_vs_WT_F02.19522.19522.3 2.92E-07 16/56 R.AIMEMPSFYSHGLPR[166.11].C "sp|P55265|DSRAD_HUMAN,tr|A0A3B3ITG9|A0A3B3ITG9_HUMAN,tr|A0A3B3IRQ9|A0A3B3IRQ9_HUMAN,tr|A0A3B3ISU1|A0A3B3ISU1_HUMAN,tr|A0A7P0Z4K3|A0A7P0Z4K3_HUMAN,tr|A0A7P0TA14|A0A7P0TA14_HUMAN,tr|A0A3B3ISX1|A0A3B3ISX1_HUMAN,tr|A0A7P0Z4F9|A0A7P0Z4F9_HUMAN" 8 1744.8305 0.54 18648 19522 3 1744.827847 582.6174 Double-stranded RNA-specific adenosine deaminase OS=Homo sapiens OX=9606 GN=ADAR PE=1 SV=4 6.79 3423.9 - 3.35E+06 - - - -1.4936 - 2.779 0.542 - 332.9 1 2 0 -0.0026 15 0 0 0 1.47E+07 2.75E+07 - - - 7.2491 0.9688 221125_WJC_METTL3_EV_vs_WT_F02.19523.19523.3 0.0199 Oct-60 R.ELLYGGTSPTAETILK.N "sp|O95793|STAU1_HUMAN,tr|Q5JW30|Q5JW30_HUMAN" 2 1691.8982 2 18649 19523 3 1691.894427 564.9733 Double-stranded RNA-binding protein Staufen homolog 1 OS=Homo sapiens OX=9606 GN=STAU1 PE=1 SV=2 4.53 3423.9 - 2.95E+06 - - - -2.2111 - 1.698 0.149 - 90 1 2 0 -0.0037 16 0 0 0 1.50E+07 7.51E+06 - - - 1.5587 0.9998 221125_WJC_METTL3_EV_vs_WT_F02.19524.19524.2 1.90E-05 22-Oct K.EQADFALEALAK[136.11].A "sp|Q7Z406|MYH14_HUMAN,sp|P35579|MYH9_HUMAN,tr|M0QY43|M0QY43_HUMAN" 3 1312.6754 1 18650 19524 2 1312.676951 657.345 Myosin-14 OS=Homo sapiens OX=9606 GN=MYH14 PE=1 SV=2 4.14 3424 - 2.90E+06 - - - 1.1572 - 2.079 0.478 - 303.4 1 2 0 0.0015 12 0 0 0 8.99E+07 9.02E+07 - - - 4.4968 1 221125_WJC_METTL3_EV_vs_WT_F02.19525.19525.2 3.13E-08 13/24 K.LEGTEDLSDVLVR.Q "sp|Q15003|CND2_HUMAN,tr|E9PHA2|E9PHA2_HUMAN,tr|H7C415|H7C415_HUMAN" 3 1444.7409 2.02 18651 19525 2 1444.741502 723.3777 Condensin complex subunit 2 OS=Homo sapiens OX=9606 GN=NCAPH PE=1 SV=3 3.92 3424.1 - 1.93E+06 - - - 0.3897 - 2.843 0.588 - 692 1 2 0 0.0006 13 0 0 0 2.81E+07 1.39E+07 - - - 6.0655 0.9998 221125_WJC_METTL3_EV_vs_WT_F02.19526.19526.2 0.000136 20-Nov K.EVFSMAGVVVR.A "sp|P52272|HNRPM_HUMAN,tr|M0R019|M0R019_HUMAN,tr|M0R0N3|M0R0N3_HUMAN,tr|A0A087X0X3|A0A087X0X3_HUMAN,tr|M0QZM1|M0QZM1_HUMAN,tr|M0QYQ7|M0QYQ7_HUMAN,tr|M0R2T0|M0R2T0_HUMAN" 7 1192.6274 1.6 18652 19526 2 1192.626447 597.321 Heterogeneous nuclear ribonucleoprotein M OS=Homo sapiens OX=9606 GN=HNRNPM PE=1 SV=3 6.1 3424.2 - 1.49E+06 - - - -0.8234 - 1.974 0.418 - 380.8 1 2 0 -0.001 11 0 0 0 6.10E+07 3.82E+07 - - - 3.9678 0.9927 221125_WJC_METTL3_EV_vs_WT_F02.19529.19529.3 0.126 Aug-60 R.ELLYGGTSPTAETILK[136.11].N "sp|O95793|STAU1_HUMAN,tr|Q5JW30|Q5JW30_HUMAN" 2 1699.9124 2.71 18655 19529 3 1699.914266 567.6447 Double-stranded RNA-binding protein Staufen homolog 1 OS=Homo sapiens OX=9606 GN=STAU1 PE=1 SV=2 4.53 3424.4 - 1.14E+06 - - - 1.1165 - 1.582 0.226 - 47.7 2 2 0 0.0019 16 0 0 0 2.09E+07 7.73E+06 - - - 2.0968 0.999 221125_WJC_METTL3_EV_vs_WT_F02.19530.19530.2 0.0491 16-Jul R.GAGWLFGAK.V sp|O00743|PPP6_HUMAN 1 905.4759 0.74 18656 19530 2 905.475623 453.7452 Serine\threonine-protein phosphatase 6 catalytic subunit OS=Homo sapiens OX=9606 GN=PPP6C PE=1 SV=1 8.75 3424.5 - 649364 - - - -0.3479 - 1.453 0.306 - 168.6 1 2 0 -0.0003 9 0 0 0 4.62E+06 6.26E+06 - - - 2.382 0.9991 221125_WJC_METTL3_EV_vs_WT_F02.19531.19531.2 5.85E-05 12-Sep R.NDWLDLR.V "sp|Q6RFH5|WDR74_HUMAN,tr|E9PS41|E9PS41_HUMAN" 2 930.4559 1.25 18657 19531 2 930.458962 466.2352 WD repeat-containing protein 74 OS=Homo sapiens OX=9606 GN=WDR74 PE=1 SV=1 4.21 3424.7 - 630305 - - - 3.2586 - 1.832 0.454 - 415.2 1 2 0 0.003 7 0 0 0 7.57E+06 6.06E+06 - - - 4.3116 0.9999 221125_WJC_METTL3_EV_vs_WT_F02.19532.19532.2 8.77E-06 30-Aug R.IMYDLTSKPPGTTEWE.- sp|P49915|GUAA_HUMAN 1 1866.871 0.82 18658 19532 2 1866.871535 934.4428 GMP synthase [glutamine-hydrolyzing] OS=Homo sapiens OX=9606 GN=GMPS PE=1 SV=1 4.43 3424.8 - 612496 - - - 0.3043 - 1.893 0.607 - 122.6 1 2 0 0.0006 16 0 0 0 5.81E+06 7.08E+06 - - - 5.0931 0.9994 221125_WJC_METTL3_EV_vs_WT_F02.19534.19534.3 0.00197 13/44 R.QPQVAELLAEAR[166.11].R "sp|P51570|GALK1_HUMAN,tr|K7ERJ9|K7ERJ9_HUMAN,tr|K7ERN9|K7ERN9_HUMAN,tr|K7EII7|K7EII7_HUMAN" 4 1333.7229 1.82 18660 19534 3 1333.72512 445.5816 Galactokinase OS=Homo sapiens OX=9606 GN=GALK1 PE=1 SV=1 4.53 3425.1 - 495764 - - - 1.639 - 1.754 0.35 - 206.1 1 2 0 0.0022 12 0 0 0 2.33E+07 1.28E+07 - - - 3.999 0.9994 221125_WJC_METTL3_EV_vs_WT_F02.19538.19538.2 6.67E-07 22-Dec R.QPQVAELLAEAR.R "sp|P51570|GALK1_HUMAN,tr|K7ERJ9|K7ERJ9_HUMAN,tr|K7ERN9|K7ERN9_HUMAN,tr|K7EII7|K7EII7_HUMAN" 4 1323.7147 1.76 18662 19538 2 1323.718786 662.8646 Galactokinase OS=Homo sapiens OX=9606 GN=GALK1 PE=1 SV=1 4.53 3425.6 - 5.22E+06 - - - 3.114 - 2.011 0.551 - 488.4 1 2 0 0.0041 12 0 0 0 1.04E+08 5.91E+07 - - - 4.9476 0.9987 221125_WJC_METTL3_EV_vs_WT_F02.19539.19539.2 6.79E-05 22-Nov R.QPQVAELLAEAR[166.11].R "sp|P51570|GALK1_HUMAN,tr|K7ERJ9|K7ERJ9_HUMAN,tr|K7ERN9|K7ERN9_HUMAN,tr|K7EII7|K7EII7_HUMAN" 4 1333.7229 2 18663 19539 2 1333.727857 667.8687 Galactokinase OS=Homo sapiens OX=9606 GN=GALK1 PE=1 SV=1 4.53 3425.7 - 2.92E+06 - - - 3.6912 - 1.975 0.473 - 399.3 1 2 0 0.0049 12 0 0 0 1.25E+08 6.24E+07 - - - 4.3237 1 221125_WJC_METTL3_EV_vs_WT_F02.19541.19541.3 1.90E-08 17/68 K.VLVYNNTSIVQDEILAHR[166.11].L "sp|O15160|RPAC1_HUMAN,tr|D6RDJ3|D6RDJ3_HUMAN,tr|A0A2R8YEZ4|A0A2R8YEZ4_HUMAN,tr|H0Y723|H0Y723_HUMAN,tr|E7EQB9|E7EQB9_HUMAN,tr|A0A2R8Y5D3|A0A2R8Y5D3_HUMAN,tr|A0A2R8YEY5|A0A2R8YEY5_HUMAN,tr|A0A2R8Y8D6|A0A2R8Y8D6_HUMAN" 8 2093.1145 0.27 18665 19541 3 2093.115421 698.7121 DNA-directed RNA polymerases I and III subunit RPAC1 OS=Homo sapiens OX=9606 GN=POLR1C PE=1 SV=1 5.32 3425.8 - 2.51E+06 - - - 0.4524 - 3.245 0.574 - 323 1 2 0 0.0009 18 0 0 0 2.18E+07 8.21E+07 - - - 7.8704 0.9277 221125_WJC_METTL3_EV_vs_WT_F02.19544.19544.2 0.00269 20-Aug R.SLHDALC[160.03]VLAQ.T "sp|P78371|TCPB_HUMAN,tr|F8VQ14|F8VQ14_HUMAN,tr|F5GWF6|F5GWF6_HUMAN" 3 1225.6125 - 18668 19544 2 1225.615147 613.8135 T-complex protein 1 subunit beta OS=Homo sapiens OX=9606 GN=CCT2 PE=1 SV=4 5.06 3426.1 - 1.75E+06 - - - 2.1532 - 1.757 0.331 - 195 1 1 0 0.0026 11 0 0 0 - - - - - 3.0096 1 221125_WJC_METTL3_EV_vs_WT_F02.19545.19545.3 6.22E-13 19/72 K.VLDAPGGGSVLVMEHMDMR[166.11].H "sp|Q9HA64|KT3K_HUMAN,tr|I3L3W5|I3L3W5_HUMAN,tr|I3L2G3|I3L2G3_HUMAN,tr|I3L139|I3L139_HUMAN" 4 2022.9565 0.29 18669 19545 3 2022.958929 675.3261 Ketosamine-3-kinase OS=Homo sapiens OX=9606 GN=FN3KRP PE=1 SV=2 4.54 3426.1 - 1.52E+06 - - - 1.2215 - 3.513 0.621 - 409.2 1 2 0 0.0025 19 0 0 0 2.57E+06 8.98E+06 - - - 8.5498 1 221125_WJC_METTL3_EV_vs_WT_F02.19548.19548.2 2.06E-08 20/28 R.NVQAEEMVEFSSGLK.G "sp|P25705|ATPA_HUMAN,tr|K7EQH4|K7EQH4_HUMAN,tr|K7ERX7|K7ERX7_HUMAN,tr|K7EK77|K7EK77_HUMAN,tr|K7EJP1|K7EJP1_HUMAN" 5 1666.7872 1.36 18672 19548 2 1666.789706 834.4009 "ATP synthase subunit alpha, mitochondrial OS=Homo sapiens OX=9606 GN=ATP5F1A PE=1 SV=1" 4.25 3426.5 - 1.19E+06 - - - 1.4813 - 3.366 0.663 - 1269.8 1 2 0 0.0025 15 0 0 0 6.00E+07 4.43E+07 - - - 6.9211 1 221125_WJC_METTL3_EV_vs_WT_F02.19552.19552.2 3.46E-05 17/30 K.LADFGVAGQLTDTQIK[136.11].R "sp|Q9P289|STK26_HUMAN,sp|O00506|STK25_HUMAN,sp|Q9Y6E0|STK24_HUMAN,tr|C9JDH9|C9JDH9_HUMAN,tr|C9J232|C9J232_HUMAN,tr|B4E0Y9|B4E0Y9_HUMAN,tr|B4DR80|B4DR80_HUMAN,tr|C9JJV0|C9JJV0_HUMAN,tr|Q8NBY1|Q8NBY1_HUMAN,tr|H7C279|H7C279_HUMAN,tr|C9JCC0|C9JCC0_HUMAN,tr|H0Y630|H0Y630_HUMAN,tr|C9J6L2|C9J6L2_HUMAN" 13 1683.8923 0.91 18676 19552 2 1683.892189 842.9534 Serine\threonine-protein kinase 26 OS=Homo sapiens OX=9606 GN=STK26 PE=1 SV=2 4.21 3427 - 913118 - - - -0.0665 - 3.229 0.544 - 1057.7 1 2 0 -0.0001 16 0 0 0 8.74E+06 9.65E+06 - - - 5.9408 1 221125_WJC_METTL3_EV_vs_WT_F02.19553.19553.3 1.57E-05 17/44 K.YGLIFHSTFIGR.A "sp|O00567|NOP56_HUMAN,tr|A0A494C128|A0A494C128_HUMAN,tr|H0YDU4|H0YDU4_HUMAN,tr|H0Y653|H0Y653_HUMAN" 4 1409.7456 0.94 18677 19553 3 1409.745835 470.9225 Nucleolar protein 56 OS=Homo sapiens OX=9606 GN=NOP56 PE=1 SV=4 8.75 3427.1 - 912778 - - - 0.1873 - 3.042 0.527 - 299.4 1 2 0 0.0003 12 0 0 0 1.17E+07 1.24E+07 - - - 7.4992 1 221125_WJC_METTL3_EV_vs_WT_F02.19554.19554.3 2.42E-07 14/56 R.NVQAEEMVEFSSGLK[136.11].G "sp|P25705|ATPA_HUMAN,tr|K7EQH4|K7EQH4_HUMAN,tr|K7ERX7|K7ERX7_HUMAN,tr|K7EK77|K7EK77_HUMAN,tr|K7EJP1|K7EJP1_HUMAN" 5 1674.8014 1.45 18678 19554 3 1674.804028 559.2744 "ATP synthase subunit alpha, mitochondrial OS=Homo sapiens OX=9606 GN=ATP5F1A PE=1 SV=1" 4.25 3427.2 - 669734 - - - 1.547 - 2.751 0.561 - 282.2 1 2 0 0.0026 15 0 0 0 3.14E+07 2.17E+07 - - - 7.4345 1 221125_WJC_METTL3_EV_vs_WT_F02.19556.19556.3 0.000186 13/48 K.TPSSDVLVFDYTK.H "sp|Q09028|RBBP4_HUMAN,sp|Q16576|RBBP7_HUMAN,tr|Q5JP01|Q5JP01_HUMAN,tr|H0YF10|H0YF10_HUMAN,tr|E9PC52|E9PC52_HUMAN" 5 1470.7242 1.46 18680 19556 3 1470.723137 491.2487 Histone-binding protein RBBP4 OS=Homo sapiens OX=9606 GN=RBBP4 PE=1 SV=3 4.21 3427.5 - 491147 - - - -0.7405 - 2.52 0.492 - 287.2 1 2 0 -0.0011 13 0 0 0 7.59E+06 5.22E+06 - - - 6.5309 0.9998 221125_WJC_METTL3_EV_vs_WT_F02.19561.19561.2 0.0018 20-Nov K.EVFSMAGVVVR[166.11].A "sp|P52272|HNRPM_HUMAN,tr|M0R019|M0R019_HUMAN,tr|M0R0N3|M0R0N3_HUMAN,tr|A0A087X0X3|A0A087X0X3_HUMAN,tr|M0QZM1|M0QZM1_HUMAN,tr|M0QYQ7|M0QYQ7_HUMAN,tr|M0R2T0|M0R2T0_HUMAN" 7 1202.6357 1.6 18684 19561 2 1202.636363 602.3251 Heterogeneous nuclear ribonucleoprotein M OS=Homo sapiens OX=9606 GN=HNRNPM PE=1 SV=3 6.1 3427.9 - 4.76E+06 - - - 0.5521 - 2.064 0.448 - 497.9 1 2 0 0.0007 11 0 0 0 6.10E+07 3.82E+07 - - - 4.3101 1 221125_WJC_METTL3_EV_vs_WT_F02.19562.19562.3 2.61E-09 17/56 R.NVQAEEMVEFSSGLK.G "sp|P25705|ATPA_HUMAN,tr|K7EQH4|K7EQH4_HUMAN,tr|K7ERX7|K7ERX7_HUMAN,tr|K7EK77|K7EK77_HUMAN,tr|K7EJP1|K7EJP1_HUMAN" 5 1666.7872 1.42 18685 19562 3 1666.789284 556.603 "ATP synthase subunit alpha, mitochondrial OS=Homo sapiens OX=9606 GN=ATP5F1A PE=1 SV=1" 4.25 3428 - 2.75E+06 - - - 1.2281 - 2.953 0.629 - 491.1 1 2 0 0.002 15 0 0 0 3.23E+07 2.28E+07 - - - 8.3776 1 221125_WJC_METTL3_EV_vs_WT_F02.19563.19563.3 1.07E-14 23/68 K.VLVYNNTSIVQDEILAHR.L "sp|O15160|RPAC1_HUMAN,tr|D6RDJ3|D6RDJ3_HUMAN,tr|A0A2R8YEZ4|A0A2R8YEZ4_HUMAN,tr|H0Y723|H0Y723_HUMAN,tr|E7EQB9|E7EQB9_HUMAN,tr|A0A2R8Y5D3|A0A2R8Y5D3_HUMAN,tr|A0A2R8YEY5|A0A2R8YEY5_HUMAN,tr|A0A2R8Y8D6|A0A2R8Y8D6_HUMAN" 8 2083.1062 0.27 18686 19563 3 2083.109273 695.376 DNA-directed RNA polymerases I and III subunit RPAC1 OS=Homo sapiens OX=9606 GN=POLR1C PE=1 SV=1 5.32 3428.1 - 2.15E+06 - - - 1.4733 - 3.953 0.667 - 649.6 1 2 0 0.0031 18 0 0 0 2.19E+07 8.21E+07 - - - 9.3981 0.9999 221125_WJC_METTL3_EV_vs_WT_F02.19564.19564.2 3.38E-07 13/20 K.YSDADIEPFLK.N "sp|Q14008|CKAP5_HUMAN,tr|H0YDX5|H0YDX5_HUMAN" 2 1296.6238 999 18687 19564 2 1296.623799 649.3192 Cytoskeleton-associated protein 5 OS=Homo sapiens OX=9606 GN=CKAP5 PE=1 SV=3 4.03 3428.1 - 2.03E+06 - - - 0.0116 - 2.512 0.446 - 371.5 1 2 0 0 11 0 0 0 1.10E+07 0.00E+00 - - - 4.8269 0.9983 221125_WJC_METTL3_EV_vs_WT_F02.19565.19565.2 0.0113 20-Oct R.EGLYITEEIYK.T "sp|P05089|ARGI1_HUMAN,tr|A0A5F9ZGN6|A0A5F9ZGN6_HUMAN,tr|A0A5F9ZH78|A0A5F9ZH78_HUMAN" 3 1356.6813 9.85 18688 19565 2 1356.685662 679.3479 Arginase-1 OS=Homo sapiens OX=9606 GN=ARG1 PE=1 SV=2 4.25 3428.2 - 1.56E+06 - - - 3.2159 - 1.989 0.357 - 309.8 1 2 0 0.0044 11 0 0 0 6.89E+07 7.00E+06 - - - 3.5366 0.9997 221125_WJC_METTL3_EV_vs_WT_F02.19566.19566.2 3.49E-05 14/26 K.NVGLDIEAEVPAVK[136.11].D "sp|P50990|TCPQ_HUMAN,tr|H7C2U0|H7C2U0_HUMAN" 2 1460.7966 0.42 18689 19566 2 1460.799034 731.4056 T-complex protein 1 subunit theta OS=Homo sapiens OX=9606 GN=CCT8 PE=1 SV=4 4.14 3428.3 - 1.34E+06 - - - 1.6594 - 2.43 0.46 - 489.1 1 2 0 0.0024 14 0 0 0 3.73E+08 8.90E+08 - - - 4.6659 0.9995 221125_WJC_METTL3_EV_vs_WT_F02.19567.19567.2 0.000351 20-Oct R.FYQVPVPLPDR[166.11].R "sp|Q9Y2R9|RT07_HUMAN,tr|J3QLS3|J3QLS3_HUMAN,tr|J3QQS1|J3QQS1_HUMAN,tr|J3KSI8|J3KSI8_HUMAN" 4 1339.7164 0.75 18690 19567 2 1339.713684 670.8655 "28S ribosomal protein S7, mitochondrial OS=Homo sapiens OX=9606 GN=MRPS7 PE=1 SV=2" 5.84 3428.4 - 1.29E+06 - - - -2.0213 - 1.718 0.475 - 313.6 1 2 0 -0.0027 11 0 0 0 8.22E+06 1.10E+07 - - - 4.0125 0.9998 221125_WJC_METTL3_EV_vs_WT_F02.19569.19569.3 6.08E-05 Nov-48 K.TPSSDVLVFDYTK[136.11].H "sp|Q09028|RBBP4_HUMAN,sp|Q16576|RBBP7_HUMAN,tr|Q5JP01|Q5JP01_HUMAN,tr|H0YF10|H0YF10_HUMAN,tr|E9PC52|E9PC52_HUMAN" 5 1478.7384 2.32 18692 19569 3 1478.739979 493.9201 Histone-binding protein RBBP4 OS=Homo sapiens OX=9606 GN=RBBP4 PE=1 SV=3 4.21 3428.6 - 997239 - - - 1.0502 - 2.291 0.368 - 192.6 1 2 0 0.0016 13 0 0 0 1.31E+07 5.67E+06 - - - 4.89 1 221125_WJC_METTL3_EV_vs_WT_F02.19570.19570.3 8.72E-10 20/76 K.LAGANPAVITC[160.03]DELLLGHEK.A sp|P78527|PRKDC_HUMAN 1 2120.0936 0.17 18693 19570 3 2120.09319 707.7051 DNA-dependent protein kinase catalytic subunit OS=Homo sapiens OX=9606 GN=PRKDC PE=1 SV=3 4.65 3428.7 - 665293 - - - -0.1887 - 3.806 0.576 - 552.6 1 2 0 -0.0004 20 0 0 0 6.52E+06 3.80E+07 - - - 8.2043 0.9997 221125_WJC_METTL3_EV_vs_WT_F02.19580.19580.2 0.00349 16-Aug K.VSVNDFIIK.A "sp|O00330|ODPX_HUMAN,tr|H0YD97|H0YD97_HUMAN" 2 1033.5808 1.3 18701 19580 2 1033.581492 517.7977 "Pyruvate dehydrogenase protein X component, mitochondrial OS=Homo sapiens OX=9606 GN=PDHX PE=1 SV=3" 5.81 3430 - 2.33E+06 - - - 0.6724 - 1.905 0.361 - 175.4 1 2 0 0.0007 9 0 0 0 1.49E+07 1.15E+07 - - - 3.5716 0.9996 221125_WJC_METTL3_EV_vs_WT_F02.19581.19581.2 0.00996 16-Aug K.VSVNDFIIK[136.11].A "sp|O00330|ODPX_HUMAN,tr|H0YD97|H0YD97_HUMAN" 2 1041.595 1.27 18702 19581 2 1041.595277 521.8048 "Pyruvate dehydrogenase protein X component, mitochondrial OS=Homo sapiens OX=9606 GN=PDHX PE=1 SV=3" 5.81 3430 - 2.06E+06 - - - 0.2688 - 1.85 0.319 - 242.8 1 2 0 0.0003 9 0 0 0 1.45E+07 1.15E+07 - - - 3.1768 1 221125_WJC_METTL3_EV_vs_WT_F02.19583.19583.2 1.59E-08 16/26 R.MDSFDEDLARPSGL.L "sp|Q9Y2W1|TR150_HUMAN,tr|A0A3B3ITZ9|A0A3B3ITZ9_HUMAN" 2 1551.6875 1.22 18704 19583 2 1551.6871 776.851 Thyroid hormone receptor-associated protein 3 OS=Homo sapiens OX=9606 GN=THRAP3 PE=1 SV=2 3.84 3430.2 - 1.98E+06 - - - -0.2726 - 3.313 0.677 - 1196.6 1 1 0 -0.0004 14 0 0 0 1.54E+07 1.27E+07 - - - 7.0471 0.9992 221125_WJC_METTL3_EV_vs_WT_F02.19584.19584.2 1.85E-08 13/26 K.NVGLDIEAEVPAVK.D "sp|P50990|TCPQ_HUMAN,tr|H7C2U0|H7C2U0_HUMAN" 2 1452.7824 0.42 18705 19584 2 1452.788118 727.3985 T-complex protein 1 subunit theta OS=Homo sapiens OX=9606 GN=CCT8 PE=1 SV=4 4.14 3430.3 - 1.02E+06 - - - 3.929 - 2.53 0.577 - 365.6 1 2 0 0.0057 14 0 0 0 3.73E+08 8.90E+08 - - - 5.6302 0.9995 221125_WJC_METTL3_EV_vs_WT_F02.19585.19585.2 0.0391 22-Sep K.ALMAPNLDSFGR.D sp|Q9Y5B6|PAXB1_HUMAN 1 1290.6391 0.58 18706 19585 2 1290.639634 646.3268 PAX3- and PAX7-binding protein 1 OS=Homo sapiens OX=9606 GN=PAXBP1 PE=1 SV=2 5.88 3430.4 - 900935 - - - 0.4471 - 1.796 0.336 - 250.1 1 2 0 0.0006 12 0 0 0 4.29E+06 7.45E+06 - - - 3.0632 1 221125_WJC_METTL3_EV_vs_WT_F02.19586.19586.2 3.60E-12 19/34 R.C[160.03]ELLYEGPPDDEAAMGIK[136.11].S sp|P13639|EF2_HUMAN 1 2014.9107 0.45 18707 19586 2 2014.910464 1008.4626 Elongation factor 2 OS=Homo sapiens OX=9606 GN=EEF2 PE=1 SV=4 3.83 3430.5 - 868504 - - - -0.132 - 3.267 0.74 - 736.2 1 2 0 -0.0003 18 0 0 0 5.59E+06 1.24E+07 - - - 7.4172 0.9791 221125_WJC_METTL3_EV_vs_WT_F02.19588.19588.2 0.0015 28-Jun K.IISNASC[160.03]TTNC[160.03]LAPL.A "sp|P04406|G3P_HUMAN,tr|E7EUT5|E7EUT5_HUMAN" 2 1633.7804 - 18709 19588 2 1633.779855 817.8975 Glyceraldehyde-3-phosphate dehydrogenase OS=Homo sapiens OX=9606 GN=GAPDH PE=1 SV=3 5.51 3430.8 - 644872 - - - -0.3201 - 1.322 0.495 - 44.4 1 1 0 -0.0005 15 0 0 0 - - - - - 3.3832 0.9974 221125_WJC_METTL3_EV_vs_WT_F02.19589.19589.3 0.143 Nov-36 R.FSVLLLHGIR.F "sp|Q96IU4|ABHEB_HUMAN,tr|B4DQI4|B4DQI4_HUMAN,tr|F8W9U3|F8W9U3_HUMAN" 3 1153.6972 1.88 18710 19589 3 1153.696897 385.573 Protein ABHD14B OS=Homo sapiens OX=9606 GN=ABHD14B PE=1 SV=1 9.76 3430.9 - 587753 - - - -0.2314 - 1.53 0.258 - 148.4 1 2 0 -0.0003 10 0 0 0 2.65E+06 1.41E+06 - - - 2.6583 0.9778 221125_WJC_METTL3_EV_vs_WT_F02.19590.19590.3 0.00644 Sep-32 K.MHFVPWLAR[166.11].P "sp|Q9BZE1|RM37_HUMAN,tr|S4R369|S4R369_HUMAN" 2 1165.6094 1.19 18711 19590 3 1165.610463 389.5438 "39S ribosomal protein L37, mitochondrial OS=Homo sapiens OX=9606 GN=MRPL37 PE=1 SV=2" 9.52 3431 - 436077 - - - 0.8905 - 1.764 0.385 - 136.4 1 1 0 0.001 9 0 0 0 2.19E+06 1.84E+06 - - - 4.5427 0.9999 221125_WJC_METTL3_EV_vs_WT_F02.19591.19591.3 2.47E-06 Nov-36 R.HGLVPFAFVR.F "sp|Q13242|SRSF9_HUMAN,tr|H0YIB4|H0YIB4_HUMAN,tr|S4R3G0|S4R3G0_HUMAN" 3 1141.6396 1.24 18712 19591 3 1141.639404 381.5538 Serine\arginine-rich splicing factor 9 OS=Homo sapiens OX=9606 GN=SRSF9 PE=1 SV=1 9.76 3431.2 - 430518 - - - -0.2146 - 2.197 0.45 - 218.3 1 2 0 -0.0002 10 0 0 0 1.29E+07 1.04E+07 - - - 5.8556 0.9999 221125_WJC_METTL3_EV_vs_WT_F02.19594.19594.3 0.000159 Oct-44 K.LPQVEHVLPLLK[136.11].R sp|P42285|MTREX_HUMAN 1 1392.8584 0.89 18715 19594 3 1392.85752 465.2934 Exosome RNA helicase MTR4 OS=Homo sapiens OX=9606 GN=MTREX PE=1 SV=3 6.75 3431.6 - 324010 - - - -0.6476 - 2.119 0.453 - 107.5 1 2 0 -0.0009 12 0 0 0 1.85E+06 2.07E+06 - - - 5.6718 0.983 221125_WJC_METTL3_EV_vs_WT_F02.19595.19595.3 0.313 Aug-44 K.LPQVEHVLPLLK.R sp|P42285|MTREX_HUMAN 1 1384.8442 0.84 18716 19595 3 1384.842833 462.622 Exosome RNA helicase MTR4 OS=Homo sapiens OX=9606 GN=MTREX PE=1 SV=3 6.75 3431.7 - 320355 - - - -1.003 - 1.499 0.164 - 65.6 1 2 0 -0.0014 12 0 0 0 1.85E+06 2.19E+06 - - - 1.4901 0.8965 221125_WJC_METTL3_EV_vs_WT_F02.19597.19597.3 0.246 May-40 K.EVFSMAGVVVR.A "sp|P52272|HNRPM_HUMAN,tr|M0R019|M0R019_HUMAN,tr|M0R0N3|M0R0N3_HUMAN,tr|A0A087X0X3|A0A087X0X3_HUMAN,tr|M0QZM1|M0QZM1_HUMAN,tr|M0QYQ7|M0QYQ7_HUMAN,tr|M0R2T0|M0R2T0_HUMAN" 7 1192.6274 1.3 18718 19597 3 1192.627506 398.5498 Heterogeneous nuclear ribonucleoprotein M OS=Homo sapiens OX=9606 GN=HNRNPM PE=1 SV=3 6.1 3431.9 - 228267 - - - 0.0646 - 1.343 0.119 - 32.3 4 2 0 0.0001 11 0 0 0 1.60E+06 1.23E+06 - - - 0.4258 1 221125_WJC_METTL3_EV_vs_WT_F02.19598.19598.2 9.86E-11 Dec-40 R.LGGGMGSMNSVTGGMGMGLDR.M "tr|A0A0C4DGV1|A0A0C4DGV1_HUMAN,tr|H0YN19|H0YN19_HUMAN,tr|A0A0A0MQW0|A0A0A0MQW0_HUMAN" 3 1983.8635 1.12 18719 19598 2 1983.861641 992.939 Myelin expression factor 2 OS=Homo sapiens OX=9606 GN=MYEF2 PE=1 SV=1 5.84 3432.1 - 185954 - - - -0.9229 - 2.579 0.695 - 268.3 1 2 0 -0.0018 21 0 0 0 1.60E+06 1.43E+06 - - - 6.5029 0.9632 221125_WJC_METTL3_EV_vs_WT_F02.19601.19601.2 7.06 12-Jul K.DFDWNLK.H "sp|Q9Y5A9|YTHD2_HUMAN,sp|Q7Z739|YTHD3_HUMAN,sp|Q5VYJ5|MALR1_HUMAN,tr|A0A087X0Q1|A0A087X0Q1_HUMAN,tr|A0A024R7W5|A0A024R7W5_HUMAN,tr|U5GXS0|U5GXS0_HUMAN,tr|A0A087WY31|A0A087WY31_HUMAN" 7 936.4341 1.34 18720 19601 2 936.435326 469.2243 YTH domain-containing family protein 2 OS=Homo sapiens OX=9606 GN=YTHDF2 PE=1 SV=2 4.21 3432.5 - 1.64E+07 - - - 1.275 - 1.156 0.071 - 165.5 1 2 0 0.0012 7 0 0 0 5.18E+08 3.87E+08 - - - 0.0244 0.9699 221125_WJC_METTL3_EV_vs_WT_F02.19602.19602.2 6.49 12-Jul K.DFDWNLK[136.11].H "sp|Q9Y5A9|YTHD2_HUMAN,sp|Q7Z739|YTHD3_HUMAN,sp|Q5VYJ5|MALR1_HUMAN,tr|A0A087X0Q1|A0A087X0Q1_HUMAN,tr|A0A024R7W5|A0A024R7W5_HUMAN,tr|U5GXS0|U5GXS0_HUMAN,tr|A0A087WY31|A0A087WY31_HUMAN" 7 944.4483 1.35 18721 19602 2 944.449394 473.2314 YTH domain-containing family protein 2 OS=Homo sapiens OX=9606 GN=YTHDF2 PE=1 SV=2 4.21 3432.5 - 1.47E+07 - - - 1.1245 - 1.187 0.071 - 156 1 2 0 0.0011 7 0 0 0 5.21E+08 3.87E+08 - - - 0.1083 0.9995 221125_WJC_METTL3_EV_vs_WT_F02.19607.19607.2 2.40E-05 18-Oct K.SSAIVEIFSK.Y "sp|Q9UHB6|LIMA1_HUMAN,tr|F8VVQ7|F8VVQ7_HUMAN,tr|F8VRN8|F8VRN8_HUMAN,tr|F8VTU2|F8VTU2_HUMAN" 4 1079.5863 1.96 18726 19607 2 1079.5882 540.8004 LIM domain and actin-binding protein 1 OS=Homo sapiens OX=9606 GN=LIMA1 PE=1 SV=1 5.72 3432.8 - 2.12E+06 - - - 1.7822 - 2.102 0.351 - 391.7 1 2 0 0.0019 10 0 0 0 2.18E+07 1.11E+07 - - - 3.7065 0.9996 221125_WJC_METTL3_EV_vs_WT_F02.19608.19608.2 0.0299 16-Nov R.ESLEALLQR.A sp|O94906|PRP6_HUMAN 1 1057.5768 2.55 18727 19608 2 1057.577873 529.7957 Pre-mRNA-processing factor 6 OS=Homo sapiens OX=9606 GN=PRPF6 PE=1 SV=1 4.53 3432.9 - 1.81E+06 - - - 1.0392 - 2.274 0.311 - 430.7 1 2 0 0.0011 9 0 0 0 4.07E+07 1.60E+07 - - - 3.7145 0.9997 221125_WJC_METTL3_EV_vs_WT_F02.19609.19609.2 2.76E-05 18-Nov K.SSAIVEIFSK[136.11].Y "sp|Q9UHB6|LIMA1_HUMAN,tr|F8VVQ7|F8VVQ7_HUMAN,tr|F8VRN8|F8VRN8_HUMAN,tr|F8VTU2|F8VTU2_HUMAN" 4 1087.6005 1.96 18728 19609 2 1087.602491 544.8075 LIM domain and actin-binding protein 1 OS=Homo sapiens OX=9606 GN=LIMA1 PE=1 SV=1 5.72 3432.9 - 1.55E+06 - - - 1.8527 - 2.071 0.471 - 386.5 1 2 0 0.002 10 0 0 0 2.18E+07 1.11E+07 - - - 4.5513 0.9985 221125_WJC_METTL3_EV_vs_WT_F02.19610.19610.2 0.135 18-Aug R.HGLVPFAFVR.F "sp|Q13242|SRSF9_HUMAN,tr|H0YIB4|H0YIB4_HUMAN,tr|S4R3G0|S4R3G0_HUMAN" 3 1141.6396 1.67 18729 19610 2 1141.642144 571.8271 Serine\arginine-rich splicing factor 9 OS=Homo sapiens OX=9606 GN=SRSF9 PE=1 SV=1 9.76 3433 - 1.49E+06 - - - 2.1855 - 1.824 0.292 - 204.8 1 2 0 0.0025 10 0 0 0 4.23E+07 2.54E+07 - - - 2.8746 1 221125_WJC_METTL3_EV_vs_WT_F02.19611.19611.2 8.42E-07 14/20 R.TPLENLVLQAK[136.11].L "sp|Q7L2E3|DHX30_HUMAN,tr|H7BXY3|H7BXY3_HUMAN" 2 1232.722 0.63 18730 19611 2 1232.726449 617.3683 ATP-dependent RNA helicase DHX30 OS=Homo sapiens OX=9606 GN=DHX30 PE=1 SV=1 5.66 3433.1 - 1.32E+06 - - - 3.6188 - 2.791 0.532 - 640.3 1 2 0 0.0045 11 0 0 0 1.80E+07 2.86E+07 - - - 5.7456 1 221125_WJC_METTL3_EV_vs_WT_F02.19612.19612.2 6.24E-08 13/22 R.VFDLQFSTDSPR[166.11].L "sp|Q15003|CND2_HUMAN,tr|C9J470|C9J470_HUMAN,tr|C9JZP1|C9JZP1_HUMAN,tr|E9PHA2|E9PHA2_HUMAN" 4 1420.6862 1.15 18731 19612 2 1420.68091 711.3504 Condensin complex subunit 2 OS=Homo sapiens OX=9606 GN=NCAPH PE=1 SV=3 4.21 3433.2 - 1.15E+06 - - - -3.7341 - 2.728 0.653 - 565.6 1 2 0 -0.0053 12 0 0 0 1.26E+07 1.10E+07 - - - 6.503 1 221125_WJC_METTL3_EV_vs_WT_F02.19613.19613.2 1.62E-09 15/28 R.TPLYLQPDAYGSLDR.A sp|Q8WUF5|IASPP_HUMAN 1 1707.8468 2.95 18732 19613 2 1707.849144 854.9307 RelA-associated inhibitor OS=Homo sapiens OX=9606 GN=PPP1R13L PE=1 SV=4 4.21 3433.3 - 807818 - - - 1.3719 - 2.984 0.588 - 620.2 1 2 0 0.0023 15 0 0 0 2.08E+07 7.05E+06 - - - 6.0711 0.8475 221125_WJC_METTL3_EV_vs_WT_F02.19614.19614.2 1.13E-06 22-Nov K.MSSYAFFVQTC[160.03]R[166.11].E "sp|B2RPK0|HGB1A_HUMAN,sp|P26583|HMGB2_HUMAN,sp|P09429|HMGB1_HUMAN,tr|D6R9A6|D6R9A6_HUMAN,tr|Q5T7C4|Q5T7C4_HUMAN" 5 1505.6671 0.13 18733 19614 2 1506.679453 753.8408 Putative high mobility group protein B1-like 1 OS=Homo sapiens OX=9606 GN=HMGB1P1 PE=5 SV=1 7.98 3433.4 - 789135 - - - 672.3777 - 1.986 0.603 - 269.3 1 2 0 1.0124 12 0 0 0 2.94E+06 2.33E+07 - - - 4.9822 1 221125_WJC_METTL3_EV_vs_WT_F02.19615.19615.3 1.53E-06 14/48 R.AAFTAFEEAQLPR.L sp|Q96CT7|CC124_HUMAN 1 1449.7252 1.03 18734 19615 3 1449.727019 484.249 Coiled-coil domain-containing protein 124 OS=Homo sapiens OX=9606 GN=CCDC124 PE=1 SV=1 4.53 3433.5 - 758838 - - - 1.2347 - 2.801 0.512 - 251 1 2 0 0.0018 13 0 0 0 3.41E+07 3.30E+07 - - - 7.0404 1 221125_WJC_METTL3_EV_vs_WT_F02.19616.19616.3 4.09E-08 16/48 R.AAFTAFEEAQLPR[166.11].L sp|Q96CT7|CC124_HUMAN 1 1459.7335 1.03 18735 19616 3 1459.735548 487.5851 Coiled-coil domain-containing protein 124 OS=Homo sapiens OX=9606 GN=CCDC124 PE=1 SV=1 4.53 3433.6 - 755132 - - - 1.4037 - 2.649 0.574 - 330.8 1 2 0 0.002 13 0 0 0 3.41E+07 3.30E+07 - - - 7.5803 0.9976 221125_WJC_METTL3_EV_vs_WT_F02.19618.19618.2 2.12 12-Aug R.WLITLNK[136.11].Q "sp|P06730|IF4E_HUMAN,tr|H0Y8J7|H0Y8J7_HUMAN,tr|D6RBW1|D6RBW1_HUMAN" 3 894.5418 1.36 18737 19618 2 894.542618 448.2782 Eukaryotic translation initiation factor 4E OS=Homo sapiens OX=9606 GN=EIF4E PE=1 SV=2 8.75 3433.9 - 730462 - - - 0.8708 - 1.723 0.144 - 204.2 1 2 0 0.0008 7 0 0 0 5.28E+06 3.89E+06 - - - 1.8282 0.9999 221125_WJC_METTL3_EV_vs_WT_F02.19620.19620.3 1.91E-05 Dec-36 R.HGLVPFAFVR[166.11].F "sp|Q13242|SRSF9_HUMAN,tr|H0YIB4|H0YIB4_HUMAN,tr|S4R3G0|S4R3G0_HUMAN" 3 1151.6479 1.24 18739 19620 3 1151.648569 384.8899 Serine\arginine-rich splicing factor 9 OS=Homo sapiens OX=9606 GN=SRSF9 PE=1 SV=1 9.76 3434.1 - 680030 - - - 0.5644 - 2.071 0.465 - 225.9 1 2 0 0.0006 10 0 0 0 1.29E+07 1.04E+07 - - - 5.8503 1 221125_WJC_METTL3_EV_vs_WT_F02.19622.19622.2 9.99E-12 19/32 R.YEPVAEIGVGAYGTVYK[136.11].A "sp|P11802|CDK4_HUMAN,tr|F8VWX7|F8VWX7_HUMAN,tr|F8W1L8|F8W1L8_HUMAN,tr|F8VTV8|F8VTV8_HUMAN,tr|F8VYH9|F8VYH9_HUMAN,tr|F8VYY1|F8VYY1_HUMAN,tr|Q96BE9|Q96BE9_HUMAN" 7 1822.9233 0.26 18740 19622 2 1822.923368 912.4689 Cyclin-dependent kinase 4 OS=Homo sapiens OX=9606 GN=CDK4 PE=1 SV=2 4.53 3434.4 - 847949 - - - 0.0554 - 3.061 0.669 - 1074 1 2 0 0.0001 17 0 0 0 1.58E+06 6.13E+06 - - - 6.7327 0.9999 221125_WJC_METTL3_EV_vs_WT_F02.19623.19623.3 0.00954 Dec-44 R.SIEALLEAGQAR.D "sp|Q9P2E9|RRBP1_HUMAN,tr|A0A087WVV2|A0A087WVV2_HUMAN,tr|F8W7S5|F8W7S5_HUMAN" 3 1256.6725 1.45 18741 19623 3 1256.673303 419.8981 Ribosome-binding protein 1 OS=Homo sapiens OX=9606 GN=RRBP1 PE=1 SV=5 4.53 3434.5 - 1.42E+06 - - - 0.6668 - 2.47 0.42 - 298.6 1 2 0 0.0008 12 0 0 0 8.26E+06 5.69E+06 - - - 5.7287 1 221125_WJC_METTL3_EV_vs_WT_F02.19625.19625.2 1.20E-08 14/24 K.AQDVLVQEMEVVK[136.11].Q sp|Q99459|CDC5L_HUMAN 1 1494.7843 1.38 18743 19625 2 1494.785965 748.3994 Cell division cycle 5-like protein OS=Homo sapiens OX=9606 GN=CDC5L PE=1 SV=2 4.14 3434.6 - 4.23E+06 - - - 1.0938 - 2.829 0.602 - 706.2 1 2 0 0.0016 13 0 0 0 4.07E+07 2.95E+07 - - - 6.1559 0.9998 221125_WJC_METTL3_EV_vs_WT_F02.19626.19626.2 0.000323 13/22 R.SIEALLEAGQAR.D "sp|Q9P2E9|RRBP1_HUMAN,tr|A0A087WVV2|A0A087WVV2_HUMAN,tr|F8W7S5|F8W7S5_HUMAN" 3 1256.6725 1.22 18744 19626 2 1256.674249 629.3435 Ribosome-binding protein 1 OS=Homo sapiens OX=9606 GN=RRBP1 PE=1 SV=5 4.53 3434.6 - 3.34E+06 - - - 1.4196 - 2.636 0.431 - 625.6 1 2 0 0.0018 12 0 0 0 3.01E+07 2.47E+07 - - - 4.7741 1 221125_WJC_METTL3_EV_vs_WT_F02.19627.19627.3 3.15E-08 20/60 R.VGLADLHPDVFATAPR.L "sp|Q9BYD3|RM04_HUMAN,tr|X6RAY8|X6RAY8_HUMAN,tr|K7ES61|K7ES61_HUMAN,tr|K7ELF1|K7ELF1_HUMAN,tr|K7ELQ0|K7ELQ0_HUMAN,tr|K7EKI4|K7EKI4_HUMAN" 6 1677.8839 1.7 18745 19627 3 1677.886646 560.3019 "39S ribosomal protein L4, mitochondrial OS=Homo sapiens OX=9606 GN=MRPL4 PE=1 SV=1" 5.21 3434.6 - 3.23E+06 - - - 1.6634 - 3.167 0.551 - 333 1 2 0 0.0028 16 0 0 0 4.70E+07 2.76E+07 - - - 7.6402 0.9995 221125_WJC_METTL3_EV_vs_WT_F02.19628.19628.2 0.000971 15/22 R.SIEALLEAGQAR[166.11].D "sp|Q9P2E9|RRBP1_HUMAN,tr|A0A087WVV2|A0A087WVV2_HUMAN,tr|F8W7S5|F8W7S5_HUMAN" 3 1266.6807 1.22 18746 19628 2 1266.684364 634.3476 Ribosome-binding protein 1 OS=Homo sapiens OX=9606 GN=RRBP1 PE=1 SV=5 4.53 3434.7 - 2.85E+06 - - - 2.865 - 2.824 0.398 - 860.6 1 2 0 0.0036 12 0 0 0 3.01E+07 2.47E+07 - - - 4.711 1 221125_WJC_METTL3_EV_vs_WT_F02.19631.19631.3 1.17E-06 17/60 R.VGLADLHPDVFATAPR[166.11].L "sp|Q9BYD3|RM04_HUMAN,tr|X6RAY8|X6RAY8_HUMAN,tr|K7ES61|K7ES61_HUMAN,tr|K7ELF1|K7ELF1_HUMAN,tr|K7ELQ0|K7ELQ0_HUMAN,tr|K7EKI4|K7EKI4_HUMAN" 6 1687.8921 3.13 18749 19631 3 1687.893259 563.638 "39S ribosomal protein L4, mitochondrial OS=Homo sapiens OX=9606 GN=MRPL4 PE=1 SV=1" 5.21 3434.9 - 2.12E+06 - - - 0.6718 - 3.24 0.514 - 254.3 1 2 0 0.0011 16 0 0 0 9.43E+07 3.01E+07 - - - 7.2866 0.9991 221125_WJC_METTL3_EV_vs_WT_F02.19632.19632.2 0.00508 16-Sep R.ESLEALLQR[166.11].A sp|O94906|PRP6_HUMAN 1 1067.585 2.54 18750 19632 2 1067.587245 534.7998 Pre-mRNA-processing factor 6 OS=Homo sapiens OX=9606 GN=PRPF6 PE=1 SV=1 4.53 3434.9 - 1.96E+06 - - - 2.0617 - 1.971 0.318 - 309.3 1 2 0 0.0022 9 0 0 0 4.08E+07 1.61E+07 - - - 3.3521 0.9658 221125_WJC_METTL3_EV_vs_WT_F02.19633.19633.2 0.0136 20-Jul R.LGSLDPGWLQR.C sp|O94761|RECQ4_HUMAN 1 1240.6564 1.53 18751 19633 2 1240.663765 621.3355 ATP-dependent DNA helicase Q4 OS=Homo sapiens OX=9606 GN=RECQL4 PE=1 SV=2 5.84 3435 - 1.49E+06 - - - 5.9194 - 1.589 0.287 - 125.2 1 2 0 0.0073 11 0 0 0 1.11E+07 7.29E+06 - - - 2.4113 0.9998 221125_WJC_METTL3_EV_vs_WT_F02.19635.19635.2 6.91E-05 13/26 R.ILGLAIESQDAGIK.T "sp|O00161|SNP23_HUMAN,tr|H3BNE1|H3BNE1_HUMAN,tr|H3BR18|H3BR18_HUMAN,tr|H3BM38|H3BM38_HUMAN,tr|H3BPJ0|H3BPJ0_HUMAN" 5 1426.8031 1.63 18753 19635 2 1426.804449 714.4088 Synaptosomal-associated protein 23 OS=Homo sapiens OX=9606 GN=SNAP23 PE=1 SV=1 4.37 3435.2 - 1.13E+06 - - - 0.9139 - 2.736 0.439 - 552.1 1 2 0 0.0013 14 0 0 0 1.31E+07 8.07E+06 - - - 4.8088 0.9999 221125_WJC_METTL3_EV_vs_WT_F02.19636.19636.2 1.35E-07 13/26 R.ILGLAIESQDAGIK[136.11].T "sp|O00161|SNP23_HUMAN,tr|H3BNE1|H3BNE1_HUMAN,tr|H3BR18|H3BR18_HUMAN,tr|H3BM38|H3BM38_HUMAN,tr|H3BPJ0|H3BPJ0_HUMAN" 5 1434.8173 1.61 18754 19636 2 1434.817261 718.4159 Synaptosomal-associated protein 23 OS=Homo sapiens OX=9606 GN=SNAP23 PE=1 SV=1 4.37 3435.2 - 1.08E+06 - - - -0.0585 - 2.476 0.531 - 563.4 1 2 0 -0.0001 14 0 0 0 1.30E+07 8.07E+06 - - - 5.2381 1 221125_WJC_METTL3_EV_vs_WT_F02.19637.19637.3 0.00047 14/44 R.SIEALLEAGQAR[166.11].D "sp|Q9P2E9|RRBP1_HUMAN,tr|A0A087WVV2|A0A087WVV2_HUMAN,tr|F8W7S5|F8W7S5_HUMAN" 3 1266.6807 1.45 18755 19637 3 1266.681779 423.2342 Ribosome-binding protein 1 OS=Homo sapiens OX=9606 GN=RRBP1 PE=1 SV=5 4.53 3435.4 - 987881 - - - 0.8242 - 2.571 0.452 - 369.2 1 2 0 0.001 12 0 0 0 8.26E+06 5.69E+06 - - - 6.1965 1 221125_WJC_METTL3_EV_vs_WT_F02.19638.19638.2 5.26E-10 14/26 K.FEEYGPVIEC[160.03]DIVK.D "sp|Q9BWF3|RBM4_HUMAN,sp|Q9BQ04|RBM4B_HUMAN,tr|E9PM61|E9PM61_HUMAN,tr|D6R9K7|D6R9K7_HUMAN,tr|J3QRR5|J3QRR5_HUMAN,tr|E9PB51|E9PB51_HUMAN,tr|U3KQD5|U3KQD5_HUMAN,tr|E9PLB0|E9PLB0_HUMAN" 8 1696.8018 1.41 18756 19638 2 1696.8056 849.4082 RNA-binding protein 4 OS=Homo sapiens OX=9606 GN=RBM4 PE=1 SV=1 4 3435.5 - 985420 - - - 2.2248 - 2.749 0.675 - 583.8 1 2 0 0.0038 14 0 0 0 1.20E+08 8.48E+07 - - - 6.563 1 221125_WJC_METTL3_EV_vs_WT_F02.19640.19640.2 1.82E-07 15/28 K.FWESPETVSQLDSVR.V "sp|Q92922|SMRC1_HUMAN,tr|F8WE13|F8WE13_HUMAN" 2 1778.8475 2.98 18758 19640 2 1778.86193 890.431 SWI\SNF complex subunit SMARCC1 OS=Homo sapiens OX=9606 GN=SMARCC1 PE=1 SV=3 4.14 3435.7 - 856329 - - - 8.0957 - 3.061 0.602 - 740.1 1 2 0 0.0144 15 0 0 0 2.52E+07 8.47E+06 - - - 6.2333 0.9991 221125_WJC_METTL3_EV_vs_WT_F02.19641.19641.2 0.016 18-Sep K.GFITIVDVQR.V sp|P43304|GPDM_HUMAN 1 1146.6397 0.08 18759 19641 2 1146.638916 574.3271 "Glycerol-3-phosphate dehydrogenase, mitochondrial OS=Homo sapiens OX=9606 GN=GPD2 PE=1 SV=3" 5.84 3435.9 - 709256 - - - -0.6907 - 1.719 0.266 - 167.6 1 2 0 -0.0008 10 0 0 0 5.69E+06 6.86E+07 - - - 2.5176 0.9999 221125_WJC_METTL3_EV_vs_WT_F02.19643.19643.3 0.000389 13/48 K.AQDVLVQEMEVVK.Q sp|Q99459|CDC5L_HUMAN 1 1486.7701 1.39 18760 19643 3 1486.770972 496.5973 Cell division cycle 5-like protein OS=Homo sapiens OX=9606 GN=CDC5L PE=1 SV=2 4.14 3436.2 - 731929 - - - 0.5663 - 2.267 0.423 - 259.3 1 2 0 0.0008 13 0 0 0 4.27E+06 3.08E+06 - - - 5.4749 1 221125_WJC_METTL3_EV_vs_WT_F02.19645.19645.2 2.83E-08 26-Dec R.FTQAGSEVSALLGR.L "sp|P06576|ATPB_HUMAN,tr|F8W0P7|F8W0P7_HUMAN,tr|H0YH81|H0YH81_HUMAN" 3 1434.7467 2.27 18762 19645 2 1434.74758 718.3806 "ATP synthase subunit beta, mitochondrial OS=Homo sapiens OX=9606 GN=ATP5F1B PE=1 SV=3" 6 3436.4 - 3.22E+06 - - - 0.6182 - 2.745 0.627 - 476.3 1 2 0 0.0009 14 0 0 0 2.59E+08 1.14E+08 - - - 6.2057 0.8332 221125_WJC_METTL3_EV_vs_WT_F02.19646.19646.2 0.0801 20-Oct K.SEIEYYAMLAK[136.11].T "sp|P62888|RL30_HUMAN,tr|E5RI99|E5RI99_HUMAN" 2 1324.6464 0.46 18763 19646 2 1325.651669 663.3305 60S ribosomal protein L30 OS=Homo sapiens OX=9606 GN=RPL30 PE=1 SV=2 4.53 3436.4 - 2.25E+06 - - - 758.8659 - 1.425 0.244 - 166.4 1 2 0 1.0052 11 0 0 0 5.08E+07 1.11E+08 - - - 1.4857 0.9999 221125_WJC_METTL3_EV_vs_WT_F02.19647.19647.2 1.23E-05 13/22 R.VISFEEQVASIR[166.11].Q "sp|Q9BT78|CSN4_HUMAN,tr|D6RFN0|D6RFN0_HUMAN,tr|D6RAX7|D6RAX7_HUMAN" 3 1386.7383 0.27 18764 19647 2 1386.738044 694.3764 COP9 signalosome complex subunit 4 OS=Homo sapiens OX=9606 GN=COPS4 PE=1 SV=1 4.53 3436.5 - 1.42E+06 - - - -0.1486 - 2.256 0.528 - 589.5 1 2 0 -0.0002 12 0 0 0 6.32E+06 2.35E+07 - - - 5.0814 0.9997 221125_WJC_METTL3_EV_vs_WT_F02.19648.19648.3 0.0016 Dec-52 R.FTQAGSEVSALLGR.L "sp|P06576|ATPB_HUMAN,tr|F8W0P7|F8W0P7_HUMAN,tr|H0YH81|H0YH81_HUMAN" 3 1434.7467 1.8 18765 19648 3 1434.745487 479.2562 "ATP synthase subunit beta, mitochondrial OS=Homo sapiens OX=9606 GN=ATP5F1B PE=1 SV=3" 6 3436.6 - 1.15E+06 - - - -0.8406 - 1.944 0.353 - 199.6 1 2 0 -0.0012 14 0 0 0 6.06E+07 3.37E+07 - - - 4.2419 0.9252 221125_WJC_METTL3_EV_vs_WT_F02.19649.19649.3 0.0641 Sep-56 R.VLSGEFQIVNPHLLK[136.11].D "sp|P23921|RIR1_HUMAN,tr|E9PL69|E9PL69_HUMAN" 2 1700.9705 0.53 18766 19649 3 1700.974714 567.9974 Ribonucleoside-diphosphate reductase large subunit OS=Homo sapiens OX=9606 GN=RRM1 PE=1 SV=1 6.72 3436.7 - 1.11E+06 - - - 2.4821 - 1.578 0.129 - 67.9 1 2 0 0.0042 15 0 0 0 4.06E+06 7.72E+06 - - - 1.1673 0.9997 221125_WJC_METTL3_EV_vs_WT_F02.19650.19650.2 1.13E-06 22-Nov R.VFIGNLNTALVK[136.11].K "sp|Q9UKM9|RALY_HUMAN,sp|Q86SE5|RALYL_HUMAN,tr|Q5QPM0|Q5QPM0_HUMAN,tr|Q5QPM2|Q5QPM2_HUMAN,tr|Q5QPM1|Q5QPM1_HUMAN,tr|E5RG71|E5RG71_HUMAN,tr|Q5QPL9|Q5QPL9_HUMAN,tr|B3KT61|B3KT61_HUMAN,tr|E5RIX9|E5RIX9_HUMAN" 9 1295.7693 0.48 18767 19650 2 1295.772602 648.8919 RNA-binding protein Raly OS=Homo sapiens OX=9606 GN=RALY PE=1 SV=1 8.72 3436.8 - 946076 - - - 2.5691 - 2.134 0.56 - 314.4 1 2 0 0.0033 12 0 0 0 1.08E+07 2.23E+07 - - - 5.1705 0.9992 221125_WJC_METTL3_EV_vs_WT_F02.19651.19651.2 0.000174 14/22 K.TVSQIISLQTLK[136.11].K "sp|O76021|RL1D1_HUMAN,tr|J3QSV6|J3QSV6_HUMAN,tr|I3L3C4|I3L3C4_HUMAN,tr|I3L234|I3L234_HUMAN,tr|I3L3U9|I3L3U9_HUMAN" 5 1337.801 0.77 18768 19651 2 1337.799383 669.9078 Ribosomal L1 domain-containing protein 1 OS=Homo sapiens OX=9606 GN=RSL1D1 PE=1 SV=3 8.41 3436.9 - 898116 - - - -1.184 - 2.252 0.223 - 553.1 1 2 0 -0.0016 12 0 0 0 5.84E+06 7.62E+06 - - - 2.8236 0.9785 221125_WJC_METTL3_EV_vs_WT_F02.19652.19652.3 0.01 Dec-36 K.IAVMELFR[166.11]PK[136.11].G "sp|Q16531|DDB1_HUMAN,tr|F5GWI0|F5GWI0_HUMAN,tr|F5H198|F5H198_HUMAN,tr|A0A7P0TAX4|A0A7P0TAX4_HUMAN,tr|F5H2L3|F5H2L3_HUMAN,tr|A0A7P0TAK7|A0A7P0TAK7_HUMAN,tr|A0A7P0T870|A0A7P0T870_HUMAN,tr|A0A7P0TB30|A0A7P0TB30_HUMAN,tr|A0A7P0Z3Z5|A0A7P0Z3Z5_HUMAN,tr|F5GZY8|F5GZY8_HUMAN,tr|F5GY55|F5GY55_HUMAN,tr|A0A7P0Z4B9|A0A7P0Z4B9_HUMAN,tr|A0A7P0Z4L2|A0A7P0Z4L2_HUMAN,tr|A0A7P0T965|A0A7P0T965_HUMAN" 14 1220.707 1.01 18769 19652 3 1220.71317 407.9096 DNA damage-binding protein 1 OS=Homo sapiens OX=9606 GN=DDB1 PE=1 SV=1 8.75 3437 - 892578 - - - 5.0381 - 1.835 0.253 - 160.2 1 2 0 0.0062 10 0 0 0 8.40E+06 8.28E+06 - - - 3.1318 0.984 221125_WJC_METTL3_EV_vs_WT_F02.19653.19653.3 0.454 Nov-36 K.IAVMELFRPK.G "sp|Q16531|DDB1_HUMAN,tr|F5GWI0|F5GWI0_HUMAN,tr|F5H198|F5H198_HUMAN,tr|A0A7P0TAX4|A0A7P0TAX4_HUMAN,tr|F5H2L3|F5H2L3_HUMAN,tr|A0A7P0TAK7|A0A7P0TAK7_HUMAN,tr|A0A7P0T870|A0A7P0T870_HUMAN,tr|A0A7P0TB30|A0A7P0TB30_HUMAN,tr|A0A7P0Z3Z5|A0A7P0Z3Z5_HUMAN,tr|F5GZY8|F5GZY8_HUMAN,tr|F5GY55|F5GY55_HUMAN,tr|A0A7P0Z4B9|A0A7P0Z4B9_HUMAN,tr|A0A7P0Z4L2|A0A7P0Z4L2_HUMAN,tr|A0A7P0T965|A0A7P0T965_HUMAN" 14 1202.6845 0.97 18770 19653 3 1202.684757 401.9021 DNA damage-binding protein 1 OS=Homo sapiens OX=9606 GN=DDB1 PE=1 SV=1 8.75 3437.1 - 810893 - - - 0.1721 - 1.671 0.133 - 108.4 1 2 0 0.0002 10 0 0 0 8.40E+06 8.65E+06 - - - 1.5222 1 221125_WJC_METTL3_EV_vs_WT_F02.19654.19654.2 2.73E-08 15/28 R.TPLYLQPDAYGSLDR[166.11].A sp|Q8WUF5|IASPP_HUMAN 1 1717.8551 2.95 18771 19654 2 1717.860386 859.9348 RelA-associated inhibitor OS=Homo sapiens OX=9606 GN=PPP1R13L PE=1 SV=4 4.21 3437.3 - 808743 - - - 3.094 - 3.094 0.621 - 709.8 1 2 0 0.0053 15 0 0 0 2.08E+07 7.05E+06 - - - 6.4029 1 221125_WJC_METTL3_EV_vs_WT_F02.19655.19655.2 1.77E-10 14/28 K.FWESPETVSQLDSVR[166.11].V "sp|Q92922|SMRC1_HUMAN,tr|F8WE13|F8WE13_HUMAN" 2 1788.8558 2.98 18772 19655 2 1788.861922 895.4352 SWI\SNF complex subunit SMARCC1 OS=Homo sapiens OX=9606 GN=SMARCC1 PE=1 SV=3 4.14 3437.4 - 730804 - - - 3.4229 - 2.797 0.626 - 596.5 1 2 0 0.0061 15 0 0 0 2.52E+07 8.47E+06 - - - 6.1914 0.9477 221125_WJC_METTL3_EV_vs_WT_F02.19656.19656.2 0.0185 18-Sep K.WIGLDLSNGK.P "sp|P17987|TCPA_HUMAN,tr|F5H282|F5H282_HUMAN,tr|E7EQR6|E7EQR6_HUMAN" 3 1101.5819 -1 18773 19656 2 1101.581778 551.7982 T-complex protein 1 subunit alpha OS=Homo sapiens OX=9606 GN=TCP1 PE=1 SV=1 5.84 3437.5 - 708314 - - - -0.0735 - 1.54 0.297 - 155.3 1 1 0 -0.0001 10 0 0 0 0.00E+00 0.00E+00 - - - 2.4399 0.9999 221125_WJC_METTL3_EV_vs_WT_F02.19657.19657.3 2.91E-05 13/52 R.FWDASGVALR[166.11]PLYK[136.11].L "sp|Q15334|L2GL1_HUMAN,tr|A0A087WW77|A0A087WW77_HUMAN" 2 1639.8841 0.23 18774 19657 3 1639.88144 547.6353 Lethal(2) giant larvae protein homolog 1 OS=Homo sapiens OX=9606 GN=LLGL1 PE=1 SV=3 8.59 3437.6 - 614092 - - - -1.6422 - 2.443 0.452 - 107.4 1 2 0 -0.0027 14 0 0 0 1.33E+06 5.76E+06 - - - 5.9524 0.8935 221125_WJC_METTL3_EV_vs_WT_F02.19658.19658.3 0.626 Sep-48 K.AQDVLVQEMEVVK[136.11].Q sp|Q99459|CDC5L_HUMAN 1 1494.7843 1.74 18775 19658 3 1494.78654 499.2687 Cell division cycle 5-like protein OS=Homo sapiens OX=9606 GN=CDC5L PE=1 SV=2 4.14 3437.7 - 465136 - - - 1.4785 - 1.567 0.088 - 84.6 2 2 0 0.0022 13 0 0 0 3.79E+06 2.18E+06 - - - 0.599 0.9593 221125_WJC_METTL3_EV_vs_WT_F02.19659.19659.2 0.000882 22-Nov R.LSEQELEALELR[166.11].E sp|P52756|RBM5_HUMAN 1 1438.7543 1.09 18776 19659 2 1439.759071 720.3844 RNA-binding protein 5 OS=Homo sapiens OX=9606 GN=RBM5 PE=1 SV=2 4.09 3437.9 - 429506 - - - 698.3659 - 2.456 0.203 - 429 1 2 0 1.0048 12 0 0 0 1.92E+07 1.77E+07 - - - 2.5891 1 221125_WJC_METTL3_EV_vs_WT_F02.19660.19660.2 2.08E-09 14/26 R.TIAVDFASEDIYDK.L "sp|Q53GQ0|DHB12_HUMAN,tr|E9PI21|E9PI21_HUMAN,tr|A0A1B0GVY6|A0A1B0GVY6_HUMAN" 3 1585.7512 0.88 18777 19660 2 1585.753215 793.8829 Very-long-chain 3-oxoacyl-CoA reductase OS=Homo sapiens OX=9606 GN=HSD17B12 PE=1 SV=2 3.84 3438 - 371815 - - - 1.2902 - 2.632 0.654 - 486.6 1 2 0 0.002 14 0 0 0 9.97E+06 1.14E+07 - - - 6.2993 0.9999 221125_WJC_METTL3_EV_vs_WT_F02.19664.19664.2 2.51E-08 13/24 K.AQDVLVQEMEVVK.Q sp|Q99459|CDC5L_HUMAN 1 1486.7701 1.38 18779 19664 2 1486.770933 744.3923 Cell division cycle 5-like protein OS=Homo sapiens OX=9606 GN=CDC5L PE=1 SV=2 4.14 3438.5 - 3.47E+06 - - - 0.5401 - 2.765 0.539 - 463.8 1 2 0 0.0008 13 0 0 0 4.07E+07 2.95E+07 - - - 5.6321 0.9999 221125_WJC_METTL3_EV_vs_WT_F02.19666.19666.2 1.92E-05 18-Oct K.IIQLLDDYPK.C "sp|Q8NHW5|RLA0L_HUMAN,sp|P05388|RLA0_HUMAN,tr|G3V210|G3V210_HUMAN,tr|F8VU65|F8VU65_HUMAN,tr|F8VWS0|F8VWS0_HUMAN,tr|F8VS58|F8VS58_HUMAN,tr|F8VZS0|F8VZS0_HUMAN,tr|F8VRK7|F8VRK7_HUMAN,tr|F8VQY6|F8VQY6_HUMAN" 9 1216.6703 0.96 18781 19666 2 1216.670176 609.3424 60S acidic ribosomal protein P0-like OS=Homo sapiens OX=9606 GN=RPLP0P6 PE=5 SV=1 4.21 3438.6 - 1.04E+07 - - - -0.1348 - 2.3 0.553 - 330.7 1 2 0 -0.0002 10 0 0 0 1.50E+08 1.56E+08 - - - 5.4503 0.9999 221125_WJC_METTL3_EV_vs_WT_F02.19667.19667.2 0.000165 18-Nov K.IIQLLDDYPK[136.11].C "sp|Q8NHW5|RLA0L_HUMAN,sp|P05388|RLA0_HUMAN,tr|G3V210|G3V210_HUMAN,tr|F8VU65|F8VU65_HUMAN,tr|F8VWS0|F8VWS0_HUMAN,tr|F8VS58|F8VS58_HUMAN,tr|F8VZS0|F8VZS0_HUMAN,tr|F8VRK7|F8VRK7_HUMAN,tr|F8VQY6|F8VQY6_HUMAN" 9 1224.6845 0.94 18782 19667 2 1224.684427 613.3495 60S acidic ribosomal protein P0-like OS=Homo sapiens OX=9606 GN=RPLP0P6 PE=5 SV=1 4.21 3438.6 - 8.68E+06 - - - -0.0923 - 2.36 0.42 - 379 1 2 0 -0.0001 10 0 0 0 1.49E+08 1.59E+08 - - - 4.5399 1 221125_WJC_METTL3_EV_vs_WT_F02.19668.19668.2 2.45E-09 15/24 R.AAFTAFEEAQLPR.L sp|Q96CT7|CC124_HUMAN 1 1449.7252 0.88 18783 19668 2 1449.720602 725.8699 Coiled-coil domain-containing protein 124 OS=Homo sapiens OX=9606 GN=CCDC124 PE=1 SV=1 4.53 3438.7 - 6.23E+06 - - - -3.1916 - 2.919 0.625 - 715.3 1 2 0 -0.0046 13 0 0 0 5.49E+07 6.27E+07 - - - 6.4052 0.9992 221125_WJC_METTL3_EV_vs_WT_F02.19669.19669.2 0.000619 13/22 K.TQIALEPEQILR.Y "sp|Q16342|PDCD2_HUMAN,tr|F5H4V9|F5H4V9_HUMAN" 2 1409.7878 1.61 18784 19669 2 1409.791926 705.9012 Programmed cell death protein 2 OS=Homo sapiens OX=9606 GN=PDCD2 PE=1 SV=2 4.53 3438.7 - 3.19E+06 - - - 2.9061 - 2.496 0.366 - 534.4 1 2 0 0.0041 12 0 0 0 4.43E+07 2.75E+07 - - - 4.1497 0.9999 221125_WJC_METTL3_EV_vs_WT_F02.19670.19670.2 9.59E-06 20-Sep R.GFAYVQFEDVR[166.11].D "sp|O75494|SRS10_HUMAN,sp|Q8WXF0|SRS12_HUMAN,tr|Q5JRI1|Q5JRI1_HUMAN" 3 1339.6436 2.11 18785 19670 2 1339.642823 670.8291 Serine\arginine-rich splicing factor 10 OS=Homo sapiens OX=9606 GN=SRSF10 PE=1 SV=1 4.37 3438.8 - 2.18E+06 - - - -0.5957 - 2.248 0.539 - 372.4 1 2 0 -0.0008 11 0 0 0 6.59E+07 3.13E+07 - - - 5.2132 0.9998 221125_WJC_METTL3_EV_vs_WT_F02.19671.19671.2 0.359 22-Dec K.TQIALEPEQILR[166.11].Y "sp|Q16342|PDCD2_HUMAN,tr|F5H4V9|F5H4V9_HUMAN" 2 1419.7961 1.61 18786 19671 2 1419.797495 710.9053 Programmed cell death protein 2 OS=Homo sapiens OX=9606 GN=PDCD2 PE=1 SV=2 4.53 3438.9 - 2.14E+06 - - - 0.9832 - 2.501 0.396 - 495.3 1 2 0 0.0014 12 0 0 0 4.43E+07 2.75E+07 - - - 4.3774 0.9998 221125_WJC_METTL3_EV_vs_WT_F02.19672.19672.2 0.000118 15/28 R.SGLWAGGPAPGQFYR[166.11].L sp|P28070|PSB4_HUMAN 1 1572.7713 2.47 18787 19672 2 1572.770418 787.3929 Proteasome subunit beta type-4 OS=Homo sapiens OX=9606 GN=PSMB4 PE=1 SV=4 8.46 3438.9 - 2.14E+06 - - - -0.5493 - 3.103 0.316 - 579.1 1 2 0 -0.0009 15 0 0 0 2.27E+07 9.21E+06 - - - 4.1587 0.9998 221125_WJC_METTL3_EV_vs_WT_F02.19674.19674.2 0.0114 20-Nov R.QSVLEGLSFSR[166.11].Q "sp|Q9NZB2|F120A_HUMAN,tr|A0A0C4DG79|A0A0C4DG79_HUMAN,tr|A0A494C0Y9|A0A494C0Y9_HUMAN" 3 1231.6436 1.92 18789 19674 2 1231.643532 616.8291 Constitutive coactivator of PPAR-gamma-like protein 1 OS=Homo sapiens OX=9606 GN=FAM120A PE=1 SV=2 6 3439 - 1.52E+06 - - - -0.0723 - 2.179 0.361 - 350.9 1 2 0 -0.0001 11 0 0 0 2.68E+07 1.40E+07 - - - 3.8143 1 221125_WJC_METTL3_EV_vs_WT_F02.19675.19675.3 1.06E-06 14/40 K.LDPHLVLDQLR[166.11].C "sp|P35580|MYH10_HUMAN,sp|P35579|MYH9_HUMAN" 2 1327.7488 0.91 18790 19675 3 1327.749245 443.5902 Myosin-10 OS=Homo sapiens OX=9606 GN=MYH10 PE=1 SV=3 5.21 3439.1 - 1.47E+06 - - - 0.369 - 2.517 0.557 - 352.5 1 2 0 0.0005 11 0 0 0 2.93E+08 3.23E+08 - - - 7.3721 1 221125_WJC_METTL3_EV_vs_WT_F02.19676.19676.3 2.99E-08 17/40 K.LDPHLVLDQLR.C "sp|P35580|MYH10_HUMAN,sp|P35579|MYH9_HUMAN" 2 1317.7405 0.91 18791 19676 3 1317.739551 440.2541 Myosin-10 OS=Homo sapiens OX=9606 GN=MYH10 PE=1 SV=3 5.21 3439.3 - 1.16E+06 - - - -0.7088 - 2.647 0.525 - 491.6 1 2 0 -0.0009 11 0 0 0 2.93E+08 3.23E+08 - - - 7.1583 1 221125_WJC_METTL3_EV_vs_WT_F02.19677.19677.3 2.98E-05 17/40 R.RPLLLNSVLLR.Q sp|Q9HCS7|SYF1_HUMAN 1 1292.8292 1.65 18792 19677 3 1292.82896 431.9504 Pre-mRNA-splicing factor SYF1 OS=Homo sapiens OX=9606 GN=XAB2 PE=1 SV=2 12 3439.4 - 756171 - - - -0.2174 - 2.855 0.493 - 608.8 1 2 0 -0.0003 11 0 0 0 1.37E+07 8.30E+06 - - - 7.0166 0.9445 221125_WJC_METTL3_EV_vs_WT_F02.19678.19678.2 2.58E-06 26-Oct R.GLLQDDAHPTLVTY.A "sp|Q86U44|MTA70_HUMAN,tr|F5H6D8|F5H6D8_HUMAN,tr|H0YFV6|H0YFV6_HUMAN,tr|B4DTN4|B4DTN4_HUMAN" 4 1541.7726 - 18793 19678 2 1541.777966 771.8936 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 4.2 3439.5 - 630751 - - - 3.4979 - 1.948 0.515 - 260.1 1 1 0 0.0054 14 0 0 0 - - - - - 4.5164 0.9999 221125_WJC_METTL3_EV_vs_WT_F02.19680.19680.2 0.000847 18-Nov R.DGETLEELMK[136.11].L "sp|P13797|PLST_HUMAN,tr|A0A0A0MSQ0|A0A0A0MSQ0_HUMAN" 2 1171.5522 0.59 18795 19680 2 1171.552399 586.7834 Plastin-3 OS=Homo sapiens OX=9606 GN=PLS3 PE=1 SV=4 4 3439.8 - 568303 - - - 0.1656 - 2.023 0.487 - 322.2 1 2 0 0.0002 10 0 0 0 2.59E+06 4.39E+06 - - - 4.6046 0.9999 221125_WJC_METTL3_EV_vs_WT_F02.19681.19681.2 0.000927 14/28 K.VAAPDVVVPTLDTVR.H "sp|Q14204|DYHC1_HUMAN,tr|A0A7P0T8N2|A0A7P0T8N2_HUMAN,tr|A0A7P0T9C4|A0A7P0T9C4_HUMAN,tr|A0A7P0TBJ7|A0A7P0TBJ7_HUMAN,tr|A0A804HHY6|A0A804HHY6_HUMAN,tr|A0A7P0T9K2|A0A7P0T9K2_HUMAN,tr|A0A7P0TB64|A0A7P0TB64_HUMAN,tr|A0A2R8Y706|A0A2R8Y706_HUMAN,tr|A0A7P0T916|A0A7P0T916_HUMAN,tr|A0A7P0TB75|A0A7P0TB75_HUMAN,tr|A0A7P0T8W5|A0A7P0T8W5_HUMAN,tr|A0A7P0TAF3|A0A7P0TAF3_HUMAN,tr|A0A7P0T9F1|A0A7P0T9F1_HUMAN,tr|A0A7P0TAW9|A0A7P0TAW9_HUMAN,tr|A0A2R8YGC7|A0A2R8YGC7_HUMAN,tr|A0A7P0TA13|A0A7P0TA13_HUMAN,tr|A0A7P0TAV5|A0A7P0TAV5_HUMAN,tr|A0A7P0T7V5|A0A7P0T7V5_HUMAN,tr|A0A7P0T9R4|A0A7P0T9R4_HUMAN,tr|A0A2R8Y5T0|A0A2R8Y5T0_HUMAN,tr|A0A7P0T990|A0A7P0T990_HUMAN,tr|A0A7P0T942|A0A7P0T942_HUMAN,tr|A0A2R8YFZ7|A0A2R8YFZ7_HUMAN,tr|A0A7P0T825|A0A7P0T825_HUMAN,tr|A0A2R8Y6H2|A0A2R8Y6H2_HUMAN,tr|A0A7P0TAM4|A0A7P0TAM4_HUMAN" 26 1550.8668 1.19 18796 19681 2 1550.865922 776.4407 Cytoplasmic dynein 1 heavy chain 1 OS=Homo sapiens OX=9606 GN=DYNC1H1 PE=1 SV=5 4.21 3439.9 - 496875 - - - -0.5713 - 2.483 0.477 - 363.3 1 2 0 -0.0009 15 0 0 0 1.77E+07 1.48E+07 - - - 4.7998 0.9325 221125_WJC_METTL3_EV_vs_WT_F02.19682.19682.3 0.13 Aug-44 K.MSSYAFFVQTC[160.03]R[166.11].E "sp|B2RPK0|HGB1A_HUMAN,sp|P26583|HMGB2_HUMAN,sp|P09429|HMGB1_HUMAN,tr|D6R9A6|D6R9A6_HUMAN,tr|Q5T7C4|Q5T7C4_HUMAN" 5 1505.6671 0.68 18797 19682 3 1505.659548 502.8963 Putative high mobility group protein B1-like 1 OS=Homo sapiens OX=9606 GN=HMGB1P1 PE=5 SV=1 7.98 3440 - 443096 - - - -4.9998 - 1.494 0.238 - 63.1 1 2 0 -0.0075 12 0 0 0 1.57E+06 2.32E+06 - - - 2.3042 0.9998 221125_WJC_METTL3_EV_vs_WT_F02.19687.19687.2 0.00128 16-Sep K.AAIDWFDGK[136.11].E "sp|P35637|FUS_HUMAN,sp|Q92804|RBP56_HUMAN,tr|H3BPE7|H3BPE7_HUMAN,tr|A0A075B7D9|A0A075B7D9_HUMAN" 4 1029.5011 1.08 18801 19687 2 1029.500934 515.7578 RNA-binding protein FUS OS=Homo sapiens OX=9606 GN=FUS PE=1 SV=1 4.21 3440.6 - 4.75E+06 - - - -0.1574 - 1.834 0.43 - 242.5 1 2 0 -0.0002 9 0 0 0 3.45E+09 3.20E+09 - - - 3.9716 0.9999 221125_WJC_METTL3_EV_vs_WT_F02.19689.19689.2 8.17E-05 20-Oct R.IVLLDSSLEYK.K "sp|P49368|TCPG_HUMAN,tr|B4DUR8|B4DUR8_HUMAN,tr|Q5SZX6|Q5SZX6_HUMAN" 3 1278.7071 0.21 18803 19689 2 1278.708346 640.3608 T-complex protein 1 subunit gamma OS=Homo sapiens OX=9606 GN=CCT3 PE=1 SV=4 4.37 3440.8 - 1.80E+06 - - - 0.9596 - 2.219 0.513 - 276.4 1 2 0 0.0012 11 0 0 0 3.40E+07 1.59E+08 - - - 4.9859 0.9997 221125_WJC_METTL3_EV_vs_WT_F02.19693.19693.2 0.000217 13/20 R.ALDDFVLGSAR[166.11].L "sp|O60831|PRAF2_HUMAN,tr|A6NP52|A6NP52_HUMAN" 2 1172.6065 1.23 18807 19693 2 1172.605033 587.3105 PRA1 family protein 2 OS=Homo sapiens OX=9606 GN=PRAF2 PE=1 SV=1 4.21 3441.3 - 677852 - - - -1.2579 - 2.205 0.394 - 570.9 1 2 0 -0.0015 11 0 0 0 1.73E+07 1.40E+07 - - - 4.0897 0.9994 221125_WJC_METTL3_EV_vs_WT_F02.19694.19694.2 0.000428 28-Dec R.NLIAFSEDGSDPYVR.M "sp|A0FGR8|ESYT2_HUMAN,tr|A0A499FIX8|A0A499FIX8_HUMAN,tr|H7BXI1|H7BXI1_HUMAN,tr|A0A087WXU3|A0A087WXU3_HUMAN" 4 1681.7948 1.25 18808 19694 2 1681.800042 841.9047 Extended synaptotagmin-2 OS=Homo sapiens OX=9606 GN=ESYT2 PE=1 SV=1 4.03 3441.4 - 522064 - - - 3.1377 - 2.348 0.523 - 392.6 1 2 0 0.0053 15 0 0 0 3.44E+06 2.74E+06 - - - 5.0007 0.9997 221125_WJC_METTL3_EV_vs_WT_F02.19696.19696.2 0.0487 28-Oct R.NLIAFSEDGSDPYVR[166.11].M "sp|A0FGR8|ESYT2_HUMAN,tr|A0A499FIX8|A0A499FIX8_HUMAN,tr|H7BXI1|H7BXI1_HUMAN,tr|A0A087WXU3|A0A087WXU3_HUMAN" 4 1691.803 -1 18810 19696 2 1691.802505 846.9088 Extended synaptotagmin-2 OS=Homo sapiens OX=9606 GN=ESYT2 PE=1 SV=1 4.03 3441.6 - 443523 - - - -0.3133 - 2.174 0.344 - 221.9 1 2 0 -0.0005 15 0 0 0 0.00E+00 0.00E+00 - - - 3.4908 0.999 221125_WJC_METTL3_EV_vs_WT_F02.19699.19699.3 0.0168 Aug-32 R.FHPFC[160.03]LVLR.K "sp|Q96QA5|GSDMA_HUMAN,tr|J3KRG2|J3KRG2_HUMAN" 2 1187.6274 17.65 18813 19699 3 1187.626293 396.8831 Gasdermin-A OS=Homo sapiens OX=9606 GN=GSDMA PE=1 SV=4 8.26 3442 - 317645 - - - -0.9069 - 1.706 0.283 - 135.2 1 2 0 -0.0011 9 0 0 0 5.64E+06 3.20E+05 - - - 3.3047 1 221125_WJC_METTL3_EV_vs_WT_F02.19702.19702.2 1.97E-09 15/28 R.NVQAEEMVEFSSGLK[136.11].G "sp|P25705|ATPA_HUMAN,tr|K7EQH4|K7EQH4_HUMAN,tr|K7ERX7|K7ERX7_HUMAN,tr|K7EK77|K7EK77_HUMAN,tr|K7EJP1|K7EJP1_HUMAN" 5 1674.8014 1.36 18815 19702 2 1674.802283 838.408 "ATP synthase subunit alpha, mitochondrial OS=Homo sapiens OX=9606 GN=ATP5F1A PE=1 SV=1" 4.25 3442.3 - 412723 - - - 0.5051 - 2.837 0.638 - 589.3 1 2 0 0.0008 15 0 0 0 6.00E+07 4.43E+07 - - - 6.3166 1 221125_WJC_METTL3_EV_vs_WT_F02.19703.19703.3 8.28E-05 14/52 R.FTQAGSEVSALLGR[166.11].L "sp|P06576|ATPB_HUMAN,tr|F8W0P7|F8W0P7_HUMAN,tr|H0YH81|H0YH81_HUMAN" 3 1444.755 1.92 18816 19703 3 1444.754554 482.5923 "ATP synthase subunit beta, mitochondrial OS=Homo sapiens OX=9606 GN=ATP5F1B PE=1 SV=3" 6 3442.4 - 4.44E+06 - - - -0.2831 - 2.422 0.491 - 334.8 1 2 0 -0.0004 14 0 0 0 6.06E+07 3.16E+07 - - - 6.3649 0.9999 221125_WJC_METTL3_EV_vs_WT_F02.19708.19708.3 0.000265 Oct-52 K.FEEYGPVIEC[160.03]DIVK.D "sp|Q9BWF3|RBM4_HUMAN,sp|Q9BQ04|RBM4B_HUMAN,tr|E9PM61|E9PM61_HUMAN,tr|D6R9K7|D6R9K7_HUMAN,tr|J3QRR5|J3QRR5_HUMAN,tr|E9PB51|E9PB51_HUMAN,tr|U3KQD5|U3KQD5_HUMAN,tr|E9PLB0|E9PLB0_HUMAN" 8 1696.8018 0.56 18821 19708 3 1696.80594 566.6079 RNA-binding protein 4 OS=Homo sapiens OX=9606 GN=RBM4 PE=1 SV=1 4 3442.7 - 1.97E+06 - - - 2.4252 - 2.088 0.484 - 121.5 1 2 0 0.0041 14 0 0 0 2.12E+07 3.78E+07 - - - 5.8915 0.9999 221125_WJC_METTL3_EV_vs_WT_F02.19709.19709.3 9.86E-05 Dec-56 K.FWESPETVSQLDSVR.V "sp|Q92922|SMRC1_HUMAN,tr|F8WE13|F8WE13_HUMAN" 2 1778.8475 1.38 18822 19709 3 1778.848464 593.9565 SWI\SNF complex subunit SMARCC1 OS=Homo sapiens OX=9606 GN=SMARCC1 PE=1 SV=3 4.14 3442.8 - 1.66E+06 - - - 0.5256 - 2.439 0.448 - 219.4 1 2 0 0.0009 15 0 0 0 1.06E+07 7.70E+06 - - - 5.861 0.9957 221125_WJC_METTL3_EV_vs_WT_F02.19710.19710.3 0.00158 Jul-52 K.FEEYGPVIEC[160.03]DIVK[136.11].D "sp|Q9BWF3|RBM4_HUMAN,sp|Q9BQ04|RBM4B_HUMAN,tr|E9PM61|E9PM61_HUMAN,tr|D6R9K7|D6R9K7_HUMAN,tr|J3QRR5|J3QRR5_HUMAN,tr|E9PB51|E9PB51_HUMAN,tr|U3KQD5|U3KQD5_HUMAN,tr|E9PLB0|E9PLB0_HUMAN" 8 1704.816 0.52 18823 19710 3 1704.823344 569.2793 RNA-binding protein 4 OS=Homo sapiens OX=9606 GN=RBM4 PE=1 SV=1 4 3442.8 - 1.56E+06 - - - 4.2931 - 1.663 0.362 - 41 1 2 0 0.0073 14 0 0 0 2.16E+07 4.19E+07 - - - 3.9256 1 221125_WJC_METTL3_EV_vs_WT_F02.19711.19711.3 1.54E-05 15/56 K.MAVLANGVMNSLQDR[166.11].Y "sp|Q8N6H7|ARFG2_HUMAN,tr|G5E9L0|G5E9L0_HUMAN,tr|A0A0D9SF70|A0A0D9SF70_HUMAN" 3 1627.805 1.11 18824 19711 3 1627.801034 543.6089 ADP-ribosylation factor GTPase-activating protein 2 OS=Homo sapiens OX=9606 GN=ARFGAP2 PE=1 SV=1 5.59 3442.9 - 1.49E+06 - - - -2.4155 - 2.776 0.523 - 354.8 1 2 0 -0.0039 15 0 0 0 1.06E+07 9.53E+06 - - - 7.034 0.9998 221125_WJC_METTL3_EV_vs_WT_F02.19712.19712.2 0.0504 14/34 K.ILIVGGGVAGLASAGAAK[136.11].S "sp|Q13423|NNTM_HUMAN,tr|E9PCX7|E9PCX7_HUMAN,tr|A0A590UJM2|A0A590UJM2_HUMAN,tr|A0A590UK29|A0A590UK29_HUMAN,tr|A0A590UJI3|A0A590UJI3_HUMAN" 5 1531.9177 1.01 18825 19712 2 1531.916633 766.9661 "NAD(P) transhydrogenase, mitochondrial OS=Homo sapiens OX=9606 GN=NNT PE=1 SV=3" 8.75 3443 - 1.02E+06 - - - -0.7148 - 2.398 0.448 - 359.9 1 2 0 -0.0011 18 0 0 0 6.76E+06 6.71E+06 - - - 4.4999 0.9999 221125_WJC_METTL3_EV_vs_WT_F02.19714.19714.2 7.79E-07 26-Oct R.TIAVDFASEDIYDK[136.11].L "sp|Q53GQ0|DHB12_HUMAN,tr|E9PI21|E9PI21_HUMAN,tr|A0A1B0GVY6|A0A1B0GVY6_HUMAN" 3 1593.7654 0.88 18827 19714 2 1593.764282 797.89 Very-long-chain 3-oxoacyl-CoA reductase OS=Homo sapiens OX=9606 GN=HSD17B12 PE=1 SV=2 3.84 3443.3 - 742418 - - - -0.682 - 2.227 0.611 - 205.5 1 2 0 -0.0011 14 0 0 0 9.97E+06 1.14E+07 - - - 5.5627 0.9998 221125_WJC_METTL3_EV_vs_WT_F02.19715.19715.2 1.66E-06 22-Dec R.NLGMTDAFELGK[136.11].A "sp|P35237|SPB6_HUMAN,tr|A0A087X1N8|A0A087X1N8_HUMAN,tr|A0A024QZX5|A0A024QZX5_HUMAN,tr|A0A2R8YD12|A0A2R8YD12_HUMAN" 4 1302.6369 0.58 18828 19715 2 1302.637996 652.3257 Serpin B6 OS=Homo sapiens OX=9606 GN=SERPINB6 PE=1 SV=3 4.37 3443.4 - 712052 - - - 0.8122 - 1.946 0.531 - 380.4 1 2 0 0.0011 12 0 0 0 2.38E+06 4.09E+06 - - - 4.7144 0.9996 221125_WJC_METTL3_EV_vs_WT_F02.19717.19717.2 1.32E-07 14/28 R.LGTLEQEATADVEWR[166.11].W "sp|Q96G21|IMP4_HUMAN,tr|E7ENR5|E7ENR5_HUMAN,tr|H0Y714|H0Y714_HUMAN" 3 1726.8401 1.37 18830 19717 2 1726.835254 864.4274 U3 small nucleolar ribonucleoprotein protein IMP4 OS=Homo sapiens OX=9606 GN=IMP4 PE=1 SV=1 4 3443.7 - 628434 - - - -2.8347 - 3.006 0.448 - 755.1 1 2 0 -0.0049 15 0 0 0 9.97E+06 7.28E+06 - - - 5.0543 0.9998 221125_WJC_METTL3_EV_vs_WT_F02.19719.19719.2 0.00111 18-Oct K.FAAQELIEVK[136.11].R "sp|Q86U44|MTA70_HUMAN,tr|F5H6D8|F5H6D8_HUMAN,tr|H0YFV6|H0YFV6_HUMAN,tr|B4DTN4|B4DTN4_HUMAN" 4 1154.6427 0 18831 19719 2 1154.642678 578.3286 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 4.53 3443.9 - 4.43E+06 - - - 0.0026 - 2.087 0.429 - 275.7 1 2 0 0 10 0 0 0 1.16E+05 1.49E+08 - - - 4.2632 0.9999 221125_WJC_METTL3_EV_vs_WT_F02.19721.19721.3 0.000971 13/52 K.NVGLDIEAEVPAVK[136.11].D "sp|P50990|TCPQ_HUMAN,tr|H7C2U0|H7C2U0_HUMAN" 2 1460.7966 0.49 18832 19721 3 1460.795539 487.9395 T-complex protein 1 subunit theta OS=Homo sapiens OX=9606 GN=CCT8 PE=1 SV=4 4.14 3444.1 - 2.88E+06 - - - -0.7332 - 2.358 0.372 - 206.6 1 2 0 -0.0011 14 0 0 0 2.88E+07 5.93E+07 - - - 4.9668 0.999 221125_WJC_METTL3_EV_vs_WT_F02.19722.19722.2 0.00155 16-Oct R.YLDVSILGK[136.11].F sp|Q86U44|MTA70_HUMAN 1 1014.5841 0.04 18833 19722 2 1014.580886 508.2993 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 5.83 3444.1 - 2.62E+06 - - - -3.1658 - 1.805 0.446 - 232 1 2 0 -0.0032 9 0 0 0 3.54E+06 8.91E+07 - - - 4.0427 1 221125_WJC_METTL3_EV_vs_WT_F02.19723.19723.2 2.75E-06 26-Dec K.FEEYGPVIEC[160.03]DIVK[136.11].D "sp|Q9BWF3|RBM4_HUMAN,sp|Q9BQ04|RBM4B_HUMAN,tr|E9PM61|E9PM61_HUMAN,tr|D6R9K7|D6R9K7_HUMAN,tr|J3QRR5|J3QRR5_HUMAN,tr|E9PB51|E9PB51_HUMAN,tr|U3KQD5|U3KQD5_HUMAN,tr|E9PLB0|E9PLB0_HUMAN" 8 1704.816 1.41 18834 19723 2 1704.815163 853.4153 RNA-binding protein 4 OS=Homo sapiens OX=9606 GN=RBM4 PE=1 SV=1 4 3444.2 - 3.73E+06 - - - -0.5056 - 2.394 0.61 - 425.6 1 2 0 -0.0009 14 0 0 0 1.20E+08 8.48E+07 - - - 5.7369 1 221125_WJC_METTL3_EV_vs_WT_F02.19724.19724.2 2.82E-06 16/28 K.MAVLANGVMNSLQDR[166.11].Y "sp|Q8N6H7|ARFG2_HUMAN,tr|G5E9L0|G5E9L0_HUMAN,tr|A0A0D9SF70|A0A0D9SF70_HUMAN" 3 1627.805 1.34 18835 19724 2 1627.799866 814.9098 ADP-ribosylation factor GTPase-activating protein 2 OS=Homo sapiens OX=9606 GN=ARFGAP2 PE=1 SV=1 5.59 3444.3 - 2.09E+06 - - - -3.1331 - 3.229 0.591 - 769.8 1 2 0 -0.0051 15 0 0 0 2.15E+07 1.61E+07 - - - 6.2864 0.9998 221125_WJC_METTL3_EV_vs_WT_F02.19726.19726.2 0.0171 13/20 R.ALDDFVLGSAR.L "sp|O60831|PRAF2_HUMAN,tr|A6NP52|A6NP52_HUMAN" 2 1162.5982 1.32 18837 19726 2 1162.598575 582.3064 PRA1 family protein 2 OS=Homo sapiens OX=9606 GN=PRAF2 PE=1 SV=1 4.21 3444.5 - 1.65E+06 - - - 0.2899 - 2.394 0.396 - 671.6 1 2 0 0.0003 11 0 0 0 1.73E+07 1.31E+07 - - - 4.3273 1 221125_WJC_METTL3_EV_vs_WT_F02.19732.19732.2 9.09E-07 22-Nov K.ETFLTSPEELYR[166.11].V "sp|O95433|AHSA1_HUMAN,tr|H0YJ63|H0YJ63_HUMAN,tr|G3V438|G3V438_HUMAN,tr|H0YJG7|H0YJG7_HUMAN" 4 1493.7277 1.31 18843 19732 2 1493.725542 747.8711 Activator of 90 kDa heat shock protein ATPase homolog 1 OS=Homo sapiens OX=9606 GN=AHSA1 PE=1 SV=1 4.25 3445.2 - 890695 - - - -1.4748 - 2.391 0.611 - 423.3 1 2 0 -0.0022 12 0 0 0 2.98E+08 2.28E+08 - - - 5.8468 1 221125_WJC_METTL3_EV_vs_WT_F02.19733.19733.2 1.27E-09 17/34 K.ILIVGGGVAGLASAGAAK.S "sp|Q13423|NNTM_HUMAN,tr|E9PCX7|E9PCX7_HUMAN,tr|A0A590UJM2|A0A590UJM2_HUMAN,tr|A0A590UK29|A0A590UK29_HUMAN,tr|A0A590UJI3|A0A590UJI3_HUMAN" 5 1523.9035 1.01 18844 19733 2 1523.901473 762.959 "NAD(P) transhydrogenase, mitochondrial OS=Homo sapiens OX=9606 GN=NNT PE=1 SV=3" 8.75 3445.4 - 747383 - - - -1.3485 - 3.187 0.548 - 590.9 1 2 0 -0.0021 18 0 0 0 6.76E+06 6.71E+06 - - - 5.9375 0.9998 221125_WJC_METTL3_EV_vs_WT_F02.19740.19740.2 1.25E-06 18-Oct R.EC[160.03]LNLWGYER.V sp|Q86U44|MTA70_HUMAN 1 1338.6027 0.03 18849 19740 2 1338.600505 670.3086 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 4.53 3446.2 - 9.59E+06 - - - -1.6181 - 1.98 0.546 - 536 1 2 0 -0.0022 10 0 0 0 1.36E+09 5.34E+10 - - - 4.9798 0.9999 221125_WJC_METTL3_EV_vs_WT_F02.19742.19742.2 4.26E-07 18-Nov R.YFSWAEPQLK.A "sp|Q86XN7|PRSR1_HUMAN,tr|Q5JS36|Q5JS36_HUMAN" 2 1267.6237 1.82 18851 19742 2 1267.623641 634.8191 Proline and serine-rich protein 1 OS=Homo sapiens OX=9606 GN=PROSER1 PE=1 SV=2 6 3446.2 - 3.39E+06 - - - -0.0655 - 1.996 0.481 - 395 1 2 0 -0.0001 10 0 0 0 1.38E+08 7.58E+07 - - - 4.5228 1 221125_WJC_METTL3_EV_vs_WT_F02.19744.19744.3 6.98E-06 14/48 R.IC[160.03]PVEFNPNFVAR.M sp|Q9UI30|TR112_HUMAN 1 1561.7711 1.53 18853 19744 3 1561.770165 521.5977 Multifunctional methyltransferase subunit TRM112-like protein OS=Homo sapiens OX=9606 GN=TRMT112 PE=1 SV=1 5.99 3446.4 - 2.97E+06 - - - -0.6204 - 2.655 0.542 - 309.2 1 2 0 -0.001 13 0 0 0 1.19E+08 7.79E+07 - - - 7.2299 0.9998 221125_WJC_METTL3_EV_vs_WT_F02.19746.19746.2 1.36E-05 13/24 K.QLSGSYMETLIEK.W "sp|P42694|HELZ_HUMAN,tr|J3QS41|J3QS41_HUMAN,tr|A0A075B6R3|A0A075B6R3_HUMAN" 3 1497.7385 2.67 18855 19746 2 1497.735906 749.8765 Probable helicase with zinc finger domain OS=Homo sapiens OX=9606 GN=HELZ PE=1 SV=2 4.53 3446.6 - 1.20E+06 - - - -1.7293 - 2.547 0.449 - 524.3 1 2 0 -0.0026 13 0 0 0 5.53E+07 2.07E+07 - - - 4.756 0.9998 221125_WJC_METTL3_EV_vs_WT_F02.19753.19753.3 0.00693 Aug-36 R.EC[160.03]LNLWGYER[166.11].V sp|Q86U44|MTA70_HUMAN 1 1348.6109 0.01 18860 19753 3 1348.608501 450.5443 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 4.53 3447.4 - 1.39E+07 - - - -1.8093 - 1.915 0.404 - 80 1 2 0 -0.0024 10 0 0 0 5.33E+06 4.26E+08 - - - 4.941 0.9998 221125_WJC_METTL3_EV_vs_WT_F02.19754.19754.2 1.59E-05 20-Oct K.ENLSYDLVPLK[136.11].N "sp|Q92598|HS105_HUMAN,tr|A0A0A0MSM0|A0A0A0MSM0_HUMAN,tr|R4GN69|R4GN69_HUMAN" 3 1297.7009 0.11 18861 19754 2 1297.700652 649.8577 Heat shock protein 105 kDa OS=Homo sapiens OX=9606 GN=HSPH1 PE=1 SV=1 4.37 3447.5 - 4.28E+06 - - - -0.205 - 1.813 0.487 - 285.8 1 2 0 -0.0003 11 0 0 0 2.83E+07 2.66E+08 - - - 4.2475 0.9998 221125_WJC_METTL3_EV_vs_WT_F02.19756.19756.2 2.40E-05 15/24 K.ELLALDSVDPEGR[166.11].A sp|O95817|BAG3_HUMAN 1 1422.723 0.16 18863 19756 2 1422.720035 712.3688 BAG family molecular chaperone regulator 3 OS=Homo sapiens OX=9606 GN=BAG3 PE=1 SV=3 3.92 3447.7 - 2.40E+06 - - - -2.0798 - 2.802 0.522 - 698.6 1 2 0 -0.003 13 0 0 0 5.91E+06 3.80E+07 - - - 5.5399 0.9999 221125_WJC_METTL3_EV_vs_WT_F02.19757.19757.2 4.46E-06 18/22 K.ALTSEIALLQSR[166.11].L "sp|P04843|RPN1_HUMAN,tr|B7Z4L4|B7Z4L4_HUMAN" 2 1310.7433 1.23 18864 19757 2 1310.743603 656.3789 Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit 1 OS=Homo sapiens OX=9606 GN=RPN1 PE=1 SV=1 6.05 3447.8 - 2.39E+06 - - - 0.2045 - 3.02 0.377 - 1703.5 1 2 0 0.0003 12 0 0 0 3.81E+08 3.11E+08 - - - 4.7336 1 221125_WJC_METTL3_EV_vs_WT_F02.19758.19758.2 1.81E-09 17/30 R.VINEPTAAALAYGLDK.S "sp|P38646|GRP75_HUMAN,tr|H0Y8K0|H0Y8K0_HUMAN,tr|A0A7I2V2S7|A0A7I2V2S7_HUMAN,tr|A0A7I2V2G2|A0A7I2V2G2_HUMAN,tr|A0A7I2V3F7|A0A7I2V3F7_HUMAN,tr|A0A7I2YQB2|A0A7I2YQB2_HUMAN,tr|D6RCD7|D6RCD7_HUMAN" 7 1644.8723 0.51 18865 19758 2 1644.873378 823.4434 "Stress-70 protein, mitochondrial OS=Homo sapiens OX=9606 GN=HSPA9 PE=1 SV=2" 4.37 3448 - 2.15E+06 - - - 0.6633 - 3.361 0.604 - 1022.2 1 2 0 0.0011 16 0 0 0 1.05E+09 2.07E+09 - - - 6.4821 0.9999 221125_WJC_METTL3_EV_vs_WT_F02.19759.19759.2 1.14E-08 28-Dec R.IAPPEAPVTGYMFGK[136.11].G "sp|P09874|PARP1_HUMAN,tr|A0A7I2V3E1|A0A7I2V3E1_HUMAN" 2 1584.8102 1.19 18866 19759 2 1584.807846 793.4124 Poly [ADP-ribose] polymerase 1 OS=Homo sapiens OX=9606 GN=PARP1 PE=1 SV=4 6 3448.1 - 1.40E+06 - - - -1.4544 - 2.561 0.56 - 325.4 1 2 0 -0.0023 15 0 0 0 3.59E+08 3.01E+08 - - - 5.4884 0.9998 221125_WJC_METTL3_EV_vs_WT_F02.19763.19763.2 3.17E-05 16-Sep K.AAIDWFDGK.E "sp|P35637|FUS_HUMAN,sp|Q92804|RBP56_HUMAN,tr|H3BPE7|H3BPE7_HUMAN,tr|A0A075B7D9|A0A075B7D9_HUMAN" 4 1021.4869 1.08 18868 19763 2 1021.485497 511.7507 RNA-binding protein FUS OS=Homo sapiens OX=9606 GN=FUS PE=1 SV=1 4.21 3448.6 - 1.88E+08 - - - -1.3696 - 1.967 0.527 - 276.9 1 2 0 -0.0014 9 0 0 0 3.45E+09 3.20E+09 - - - 4.8902 0.9998 221125_WJC_METTL3_EV_vs_WT_F02.19764.19764.2 8.65E-06 20-Oct K.LDPHLVLDQLR[166.11].C "sp|P35580|MYH10_HUMAN,sp|P35579|MYH9_HUMAN" 2 1327.7488 0.86 18869 19764 2 1327.749361 664.8817 Myosin-10 OS=Homo sapiens OX=9606 GN=MYH10 PE=1 SV=3 5.21 3448.7 - 4.29E+06 - - - 0.4564 - 1.793 0.476 - 283.8 1 2 0 0.0006 11 0 0 0 1.01E+08 1.17E+08 - - - 4.1361 0.9997 221125_WJC_METTL3_EV_vs_WT_F02.19765.19765.2 8.42E-05 18-Oct K.GAYDIFLNAK.E "sp|P42704|LPPRC_HUMAN,tr|A0A804HI14|A0A804HI14_HUMAN,tr|A0A804HL40|A0A804HL40_HUMAN,tr|A0A804HKJ0|A0A804HKJ0_HUMAN,tr|A0A804HKR3|A0A804HKR3_HUMAN,tr|A0A804HIN4|A0A804HIN4_HUMAN,tr|A0A804HLG8|A0A804HLG8_HUMAN,tr|A0A804HI40|A0A804HI40_HUMAN,tr|A0A804HJZ1|A0A804HJZ1_HUMAN,tr|A0A804HIQ7|A0A804HIQ7_HUMAN,tr|A0A804HK30|A0A804HK30_HUMAN,tr|A0A804HKI2|A0A804HKI2_HUMAN,tr|A0A804HJI0|A0A804HJI0_HUMAN,tr|A0A804HIG4|A0A804HIG4_HUMAN" 14 1110.571 0.46 18870 19765 2 1110.568859 556.2928 "Leucine-rich PPR motif-containing protein, mitochondrial OS=Homo sapiens OX=9606 GN=LRPPRC PE=1 SV=3" 5.83 3448.8 - 3.78E+06 - - - -1.8918 - 1.93 0.485 - 276 1 2 0 -0.0021 10 0 0 0 5.18E+07 1.12E+08 - - - 4.4579 0.9995 221125_WJC_METTL3_EV_vs_WT_F02.19766.19766.2 0.174 24-Dec K.AEVTLDGVWPTDK.T "sp|P52948|NUP98_HUMAN,tr|A0A3B3ITD8|A0A3B3ITD8_HUMAN" 2 1429.7089 999 18871 19766 2 1429.7123 715.8617 Nuclear pore complex protein Nup98-Nup96 OS=Homo sapiens OX=9606 GN=NUP98 PE=1 SV=4 4.03 3448.8 - 3.29E+06 - - - 2.3711 - 2.492 0.383 - 419.3 1 2 0 0.0034 13 0 0 0 3.83E+07 0.00E+00 - - - 4.2122 0.9988 221125_WJC_METTL3_EV_vs_WT_F02.19769.19769.2 1.05E-06 22-Dec K.QSTVLAPVIDLK[136.11].R "sp|Q96I25|SPF45_HUMAN,tr|Q5W012|Q5W012_HUMAN,tr|Q5W010|Q5W010_HUMAN,tr|Q5W011|Q5W011_HUMAN" 4 1290.7639 1.15 18874 19769 2 1290.758567 646.3892 Splicing factor 45 OS=Homo sapiens OX=9606 GN=RBM17 PE=1 SV=1 5.84 3449.1 - 1.88E+06 - - - -4.0952 - 2.372 0.487 - 491.2 1 2 0 -0.0053 12 0 0 0 6.68E+07 5.81E+07 - - - 4.909 0.9998 221125_WJC_METTL3_EV_vs_WT_F02.19773.19773.2 0.000179 13/30 R.VINEPTAAALAYGLDK[136.11].S "sp|P38646|GRP75_HUMAN,tr|H0Y8K0|H0Y8K0_HUMAN,tr|A0A7I2V2S7|A0A7I2V2S7_HUMAN,tr|A0A7I2V2G2|A0A7I2V2G2_HUMAN,tr|A0A7I2V3F7|A0A7I2V3F7_HUMAN,tr|A0A7I2YQB2|A0A7I2YQB2_HUMAN,tr|D6RCD7|D6RCD7_HUMAN" 7 1652.8865 0.51 18876 19773 2 1652.882661 827.4505 "Stress-70 protein, mitochondrial OS=Homo sapiens OX=9606 GN=HSPA9 PE=1 SV=2" 4.37 3449.6 - 2.35E+07 - - - -2.3147 - 2.898 0.539 - 428.8 1 2 0 -0.0038 16 0 0 0 1.05E+09 2.07E+09 - - - 5.6368 0.999 221125_WJC_METTL3_EV_vs_WT_F02.19778.19778.2 0.00735 18-Jul K.GTPWEGGLFK.L "sp|P63279|UBC9_HUMAN,tr|B0QYN7|B0QYN7_HUMAN,tr|H3BPC4|H3BPC4_HUMAN,tr|H3BQQ9|H3BQQ9_HUMAN" 4 1090.5447 1.73 18881 19778 2 1090.545536 546.2796 SUMO-conjugating enzyme UBC9 OS=Homo sapiens OX=9606 GN=UBE2I PE=1 SV=1 6 3450.1 - 1.25E+06 - - - 0.7253 - 1.599 0.291 - 165.6 1 2 0 0.0008 10 0 0 0 3.01E+07 1.74E+07 - - - 2.5003 0.9999 221125_WJC_METTL3_EV_vs_WT_F02.19780.19780.2 0.000514 18-Sep R.EC[160.03]LNLWGYER[166.11].V sp|Q86U44|MTA70_HUMAN 1 1348.6109 0.03 18882 19780 2 1348.610588 675.3127 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 4.53 3450.3 - 2.25E+09 - - - -0.2618 - 1.978 0.565 - 402 1 2 0 -0.0004 10 0 0 0 1.36E+09 5.34E+10 - - - 5.1179 0.9999 221125_WJC_METTL3_EV_vs_WT_F02.19781.19781.2 3.02E-08 15/28 R.IAPPEAPVTGYMFGK[136.11].G "sp|P09874|PARP1_HUMAN,tr|A0A7I2V3E1|A0A7I2V3E1_HUMAN" 2 1584.8102 1.19 18883 19781 2 1584.809171 793.4124 Poly [ADP-ribose] polymerase 1 OS=Homo sapiens OX=9606 GN=PARP1 PE=1 SV=4 6 3450.4 - 2.46E+06 - - - -0.6184 - 2.487 0.544 - 543.3 1 2 0 -0.001 15 0 0 0 3.59E+08 3.01E+08 - - - 5.2986 0.9995 221125_WJC_METTL3_EV_vs_WT_F02.19782.19782.3 0.0751 14/44 K.ALTSEIALLQSR.L "sp|P04843|RPN1_HUMAN,tr|B7Z4L4|B7Z4L4_HUMAN" 2 1300.7351 1.76 18884 19782 3 1300.732065 434.5856 Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit 1 OS=Homo sapiens OX=9606 GN=RPN1 PE=1 SV=1 6.05 3450.6 - 1.42E+06 - - - -2.3064 - 2.368 0.317 - 385.2 1 2 0 -0.003 12 0 0 0 6.42E+07 3.64E+07 - - - 4.4629 0.9999 221125_WJC_METTL3_EV_vs_WT_F02.19785.19785.2 0.000288 14/22 K.QSTVLAPVIDLK.R "sp|Q96I25|SPF45_HUMAN,tr|Q5W012|Q5W012_HUMAN,tr|Q5W010|Q5W010_HUMAN,tr|Q5W011|Q5W011_HUMAN" 4 1282.7497 1.15 18885 19785 2 1282.750553 642.3821 Splicing factor 45 OS=Homo sapiens OX=9606 GN=RBM17 PE=1 SV=1 5.84 3451 - 4.92E+06 - - - 0.7016 - 2.54 0.45 - 882.9 1 2 0 0.0009 12 0 0 0 6.68E+07 5.81E+07 - - - 4.8171 0.9995 221125_WJC_METTL3_EV_vs_WT_F02.19787.19787.2 1.72E-06 13/22 K.ETFLTSPEELYR.V "sp|O95433|AHSA1_HUMAN,tr|H0YJ63|H0YJ63_HUMAN,tr|G3V438|G3V438_HUMAN,tr|H0YJG7|H0YJG7_HUMAN" 4 1483.7195 1.31 18887 19787 2 1483.714674 742.867 Activator of 90 kDa heat shock protein ATPase homolog 1 OS=Homo sapiens OX=9606 GN=AHSA1 PE=1 SV=1 4.25 3451.1 - 6.84E+06 - - - -3.2358 - 2.463 0.565 - 635 1 2 0 -0.0048 12 0 0 0 2.98E+08 2.28E+08 - - - 5.5843 0.9996 221125_WJC_METTL3_EV_vs_WT_F02.19788.19788.2 2.15E-05 20-Nov R.ELGLPEELVSR[166.11].H sp|P49915|GUAA_HUMAN 1 1250.6746 2.17 18888 19788 2 1250.672056 626.3446 GMP synthase [glutamine-hydrolyzing] OS=Homo sapiens OX=9606 GN=GMPS PE=1 SV=1 4.25 3451.2 - 3.36E+06 - - - -2.0237 - 2.136 0.438 - 380.6 1 2 0 -0.0025 11 0 0 0 2.08E+08 9.56E+07 - - - 4.3284 1 221125_WJC_METTL3_EV_vs_WT_F02.19792.19792.2 1.75E-07 24-Dec R.IC[160.03]PVEFNPNFVAR.M sp|Q9UI30|TR112_HUMAN 1 1561.7711 1.44 18891 19792 2 1561.768548 781.8928 Multifunctional methyltransferase subunit TRM112-like protein OS=Homo sapiens OX=9606 GN=TRMT112 PE=1 SV=1 5.99 3451.7 - 4.35E+07 - - - -1.6558 - 2.203 0.667 - 506.8 1 2 0 -0.0026 13 0 0 0 1.18E+09 8.24E+08 - - - 5.9937 0.9997 221125_WJC_METTL3_EV_vs_WT_F02.19794.19794.2 1.73E-05 13/20 K.LDPHLVLDQLR.C "sp|P35580|MYH10_HUMAN,sp|P35579|MYH9_HUMAN" 2 1317.7405 0.86 18892 19794 2 1317.742709 659.8775 Myosin-10 OS=Homo sapiens OX=9606 GN=MYH10 PE=1 SV=3 5.21 3451.9 - 4.45E+06 - - - 1.6877 - 1.918 0.513 - 572.4 1 2 0 0.0022 11 0 0 0 1.01E+08 1.17E+08 - - - 4.5912 0.9997 221125_WJC_METTL3_EV_vs_WT_F02.19795.19795.3 0.0004 17/44 K.ALTSEIALLQSR[166.11].L "sp|P04843|RPN1_HUMAN,tr|B7Z4L4|B7Z4L4_HUMAN" 2 1310.7433 1.76 18893 19795 3 1310.742728 437.9217 Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit 1 OS=Homo sapiens OX=9606 GN=RPN1 PE=1 SV=1 6.05 3452 - 2.15E+06 - - - -0.4631 - 2.803 0.266 - 595.1 1 2 0 -0.0006 12 0 0 0 6.42E+07 3.64E+07 - - - 4.3624 1 221125_WJC_METTL3_EV_vs_WT_F02.19797.19797.2 8.98E-05 17/28 R.AVLVDLEPGTMDSVR.S "sp|P04350|TBB4A_HUMAN,sp|P68371|TBB4B_HUMAN,sp|Q3ZCM7|TBB8_HUMAN,tr|M0QY85|M0QY85_HUMAN,tr|M0QZL7|M0QZL7_HUMAN,tr|M0R0X0|M0R0X0_HUMAN,tr|A0A075B724|A0A075B724_HUMAN,tr|M0R278|M0R278_HUMAN,tr|M0QY37|M0QY37_HUMAN,tr|M0QX14|M0QX14_HUMAN" 10 1600.8131 0.84 18895 19797 2 1600.810796 801.4138 Tubulin beta-4A chain OS=Homo sapiens OX=9606 GN=TUBB4A PE=1 SV=2 4.03 3452.2 - 1.89E+06 - - - -1.413 - 3.184 0.543 - 774.4 1 2 0 -0.0023 15 0 0 0 4.11E+08 4.87E+08 - - - 5.8982 0.9993 221125_WJC_METTL3_EV_vs_WT_F02.19798.19798.2 0.00512 24-Nov R.VLNLPPNTIMEYK.T "sp|O60573|IF4E2_HUMAN,tr|B4E1E4|B4E1E4_HUMAN,tr|B9A044|B9A044_HUMAN,tr|B8ZZL3|B8ZZL3_HUMAN,tr|B9A023|B9A023_HUMAN,tr|B8ZZ50|B8ZZ50_HUMAN,tr|C9JEL3|C9JEL3_HUMAN" 7 1530.8116 2.33 18896 19798 2 1530.811823 766.4131 Eukaryotic translation initiation factor 4E type 2 OS=Homo sapiens OX=9606 GN=EIF4E2 PE=1 SV=1 5.97 3452.4 - 1.53E+06 - - - 0.145 - 1.75 0.31 - 313 1 2 0 0.0002 13 0 0 0 5.83E+07 2.51E+07 - - - 2.7669 0.9999 221125_WJC_METTL3_EV_vs_WT_F02.19807.19807.2 1.27E-05 16/26 K.LTVEDPVTVEYITR.F "sp|Q8TAA3|PSMA8_HUMAN,sp|O14818|PSA7_HUMAN,tr|A0A087WYS6|A0A087WYS6_HUMAN,tr|H0Y586|H0Y586_HUMAN" 4 1633.8563 0.13 18901 19807 2 1633.855908 817.9354 Proteasome subunit alpha-type 8 OS=Homo sapiens OX=9606 GN=PSMA8 PE=2 SV=3 4.14 3453.4 - 3.01E+06 - - - -0.2418 - 2.552 0.536 - 554.5 1 2 0 -0.0004 14 0 0 0 8.88E+07 7.04E+08 - - - 5.3508 0.9998 221125_WJC_METTL3_EV_vs_WT_F02.19820.19820.3 4.31E-07 16/56 R.AVLVDLEPGTMDSVR[166.11].S "sp|P04350|TBB4A_HUMAN,sp|P68371|TBB4B_HUMAN,sp|Q3ZCM7|TBB8_HUMAN,tr|M0QY85|M0QY85_HUMAN,tr|M0QZL7|M0QZL7_HUMAN,tr|M0R0X0|M0R0X0_HUMAN,tr|A0A075B724|A0A075B724_HUMAN,tr|M0R278|M0R278_HUMAN,tr|M0QY37|M0QY37_HUMAN,tr|M0QX14|M0QX14_HUMAN" 10 1610.8213 0.83 18908 19820 3 1610.813911 537.9477 Tubulin beta-4A chain OS=Homo sapiens OX=9606 GN=TUBB4A PE=1 SV=2 4.03 3454.9 - 1.89E+06 - - - -4.6045 - 2.811 0.54 - 425.7 1 2 0 -0.0074 15 0 0 0 7.04E+07 8.43E+07 - - - 7.2553 0.9999 221125_WJC_METTL3_EV_vs_WT_F02.19821.19821.3 1.76E-07 13/56 R.IAPPEAPVTGYMFGK[136.11].G "sp|P09874|PARP1_HUMAN,tr|A0A7I2V3E1|A0A7I2V3E1_HUMAN" 2 1584.8102 1.24 18909 19821 3 1584.811654 529.2773 Poly [ADP-ribose] polymerase 1 OS=Homo sapiens OX=9606 GN=PARP1 PE=1 SV=4 6 3455 - 1.87E+06 - - - 0.9484 - 2.595 0.354 - 264.6 1 2 0 0.0015 15 0 0 0 7.31E+07 5.88E+07 - - - 4.9746 0.9998 221125_WJC_METTL3_EV_vs_WT_F02.19822.19822.2 7.23E-08 14/30 K.GPVFAPPYEPLPENVK[136.11].F sp|P11387|TOP1_HUMAN 1 1760.9229 0.9 18910 19822 2 1760.919589 881.4687 DNA topoisomerase 1 OS=Homo sapiens OX=9606 GN=TOP1 PE=1 SV=2 4.53 3455.1 - 909990 - - - -1.8649 - 2.53 0.591 - 500.8 1 2 0 -0.0033 16 0 0 0 2.34E+07 2.58E+07 - - - 5.6872 0.9998 221125_WJC_METTL3_EV_vs_WT_F02.19825.19825.2 6.12E-08 14/28 R.IAPPEAPVTGYMFGK.G "sp|P09874|PARP1_HUMAN,tr|A0A7I2V3E1|A0A7I2V3E1_HUMAN" 2 1576.796 1.25 18911 19825 2 1576.792238 789.4053 Poly [ADP-ribose] polymerase 1 OS=Homo sapiens OX=9606 GN=PARP1 PE=1 SV=4 6 3455.5 - 6.61E+06 - - - -2.3548 - 2.393 0.596 - 449.9 1 2 0 -0.0037 15 0 0 0 2.48E+08 1.98E+08 - - - 5.5871 0.9999 221125_WJC_METTL3_EV_vs_WT_F02.19827.19827.2 0.016 16/28 R.AVLVDLEPGTMDSVR[166.11].S "sp|P04350|TBB4A_HUMAN,sp|P68371|TBB4B_HUMAN,sp|Q3ZCM7|TBB8_HUMAN,tr|M0QY85|M0QY85_HUMAN,tr|M0QZL7|M0QZL7_HUMAN,tr|M0R0X0|M0R0X0_HUMAN,tr|A0A075B724|A0A075B724_HUMAN,tr|M0R278|M0R278_HUMAN,tr|M0QY37|M0QY37_HUMAN,tr|M0QX14|M0QX14_HUMAN" 10 1610.8213 0.84 18913 19827 2 1610.818885 806.4179 Tubulin beta-4A chain OS=Homo sapiens OX=9606 GN=TUBB4A PE=1 SV=2 4.03 3455.7 - 1.20E+07 - - - -1.5166 - 3.22 0.479 - 730 1 2 0 -0.0024 15 0 0 0 4.11E+08 4.87E+08 - - - 5.4531 0.999 221125_WJC_METTL3_EV_vs_WT_F02.19829.19829.2 0.000379 18-Nov K.QLEELLSDMK[136.11].A "sp|Q14839|CHD4_HUMAN,sp|Q8TDI0|CHD5_HUMAN,sp|Q12873|CHD3_HUMAN,tr|A0A2R8Y4X2|A0A2R8Y4X2_HUMAN,tr|A0A2U3TZM0|A0A2U3TZM0_HUMAN,tr|A0A2R8YD40|A0A2R8YD40_HUMAN,tr|A0A2R8Y5J0|A0A2R8Y5J0_HUMAN,tr|A0A2R8Y425|A0A2R8Y425_HUMAN,tr|K7EMC0|K7EMC0_HUMAN,tr|A0A2R8YFK9|A0A2R8YFK9_HUMAN,tr|A0A0C4DGG9|A0A0C4DGG9_HUMAN,tr|A0A2R8YFD8|A0A2R8YFD8_HUMAN,tr|A0A2R8YDW2|A0A2R8YDW2_HUMAN,tr|A0A2R8Y7I0|A0A2R8Y7I0_HUMAN,tr|F5GWX5|F5GWX5_HUMAN,tr|A0A2R8Y7M9|A0A2R8Y7M9_HUMAN,tr|A0A2R8Y521|A0A2R8Y521_HUMAN,tr|A0A2R8YDJ9|A0A2R8YDJ9_HUMAN,tr|A0A2R8Y212|A0A2R8Y212_HUMAN" 19 1212.6151 0.54 18915 19829 2 1212.612794 607.3148 Chromodomain-helicase-DNA-binding protein 4 OS=Homo sapiens OX=9606 GN=CHD4 PE=1 SV=2 4.14 3455.9 - 2.78E+06 - - - -1.9347 - 2.074 0.269 - 412.3 1 2 0 -0.0023 10 0 0 0 1.53E+07 2.85E+07 - - - 3.0633 0.9998 221125_WJC_METTL3_EV_vs_WT_F02.19831.19831.2 0.000885 13/20 K.QITQLLPEDLR.K sp|Q7Z4H3|HDDC2_HUMAN 1 1324.7351 5.31 18916 19831 2 1324.733618 663.3748 5'-deoxynucleotidase HDDC2 OS=Homo sapiens OX=9606 GN=HDDC2 PE=1 SV=1 4.37 3456.1 - 3.49E+06 - - - -1.0923 - 2.399 0.427 - 754.1 1 2 0 -0.0014 11 0 0 0 9.45E+07 1.78E+07 - - - 4.5616 0.8148 221125_WJC_METTL3_EV_vs_WT_F02.19833.19833.2 0.763 14-Sep L.LTITTPLK.N "sp|Q8NEM8|CBPC3_HUMAN,tr|F8W7R4|F8W7R4_HUMAN" 2 885.5535 999 18917 19833 2 885.552935 443.784 Cytosolic carboxypeptidase 3 OS=Homo sapiens OX=9606 GN=AGBL3 PE=2 SV=2 8.75 3456.3 - 4.22E+06 - - - -0.6595 - 1.702 0.096 - 181.6 1 1 0 -0.0006 8 0 0 0 1.25E+08 0.00E+00 - - - 1.3538 0.9908 221125_WJC_METTL3_EV_vs_WT_F02.19834.19834.3 0.078 14/56 R.AVLVDLEPGTMDSVR.S "sp|P04350|TBB4A_HUMAN,sp|P68371|TBB4B_HUMAN,sp|Q3ZCM7|TBB8_HUMAN,tr|M0QY85|M0QY85_HUMAN,tr|M0QZL7|M0QZL7_HUMAN,tr|M0R0X0|M0R0X0_HUMAN,tr|A0A075B724|A0A075B724_HUMAN,tr|M0R278|M0R278_HUMAN,tr|M0QY37|M0QY37_HUMAN,tr|M0QX14|M0QX14_HUMAN" 10 1600.8131 0.83 18918 19834 3 1600.809448 534.6116 Tubulin beta-4A chain OS=Homo sapiens OX=9606 GN=TUBB4A PE=1 SV=2 4.03 3456.4 - 3.46E+06 - - - -2.2551 - 1.564 0.236 - 58.6 1 2 0 -0.0036 15 0 0 0 7.04E+07 8.43E+07 - - - 2.3372 0.999 221125_WJC_METTL3_EV_vs_WT_F02.19836.19836.2 0.313 16-Sep R.LGIQLDFEK.N "sp|Q14683|SMC1A_HUMAN,tr|G8JLG1|G8JLG1_HUMAN,tr|A0A6Q8PHC3|A0A6Q8PHC3_HUMAN" 3 1061.5757 1.14 18920 19836 2 1061.575684 531.7951 Structural maintenance of chromosomes protein 1A OS=Homo sapiens OX=9606 GN=SMC1A PE=1 SV=2 4.37 3456.6 - 2.04E+06 - - - -0.0254 - 1.765 0.222 - 163.8 1 2 0 0 9 0 0 0 5.49E+07 4.81E+07 - - - 2.3244 1 221125_WJC_METTL3_EV_vs_WT_F02.19837.19837.3 6.63E-07 17/44 R.VLDPFTIKPLDR.K "sp|P29401|TKT_HUMAN,tr|A0A0B4J1R6|A0A0B4J1R6_HUMAN" 2 1412.8028 1.31 18921 19837 3 1412.802042 471.9415 Transketolase OS=Homo sapiens OX=9606 GN=TKT PE=1 SV=3 5.93 3456.7 - 1.76E+06 - - - -0.5018 - 2.895 0.525 - 571.5 1 2 0 -0.0007 12 0 0 0 7.60E+07 5.81E+07 - - - 7.3395 0.9994 221125_WJC_METTL3_EV_vs_WT_F02.19838.19838.2 0.000202 24-Nov R.VLNLPPNTIMEYK[136.11].T "sp|O60573|IF4E2_HUMAN,tr|B4E1E4|B4E1E4_HUMAN,tr|B9A044|B9A044_HUMAN,tr|B8ZZL3|B8ZZL3_HUMAN,tr|B9A023|B9A023_HUMAN,tr|B8ZZ50|B8ZZ50_HUMAN,tr|C9JEL3|C9JEL3_HUMAN" 7 1538.8258 2.31 18922 19838 2 1538.821591 770.4202 Eukaryotic translation initiation factor 4E type 2 OS=Homo sapiens OX=9606 GN=EIF4E2 PE=1 SV=1 5.97 3456.9 - 1.32E+06 - - - -2.7359 - 2.226 0.442 - 316.5 1 2 0 -0.0042 13 0 0 0 5.78E+07 2.51E+07 - - - 4.358 0.9976 221125_WJC_METTL3_EV_vs_WT_F02.19839.19839.3 0.011 15/52 K.LTVEDPVTVEYITR.F "sp|Q8TAA3|PSMA8_HUMAN,sp|O14818|PSA7_HUMAN,tr|A0A087WYS6|A0A087WYS6_HUMAN,tr|H0Y586|H0Y586_HUMAN" 4 1633.8563 0.13 18923 19839 3 1633.863816 545.626 Proteasome subunit alpha-type 8 OS=Homo sapiens OX=9606 GN=PSMA8 PE=2 SV=3 4.14 3457 - 1.29E+06 - - - 4.5983 - 2.535 0.321 - 359.7 1 2 0 0.0075 14 0 0 0 1.93E+07 1.51E+08 - - - 4.5888 0.9999 221125_WJC_METTL3_EV_vs_WT_F02.19842.19842.2 2.22E-05 15/18 R.IC[160.03]DDELILIK[136.11].N "sp|P17987|TCPA_HUMAN,tr|F5GZ03|F5GZ03_HUMAN,tr|F5H282|F5H282_HUMAN,tr|E7EQR6|E7EQR6_HUMAN,tr|E7ERF2|E7ERF2_HUMAN" 5 1238.6672 0.56 18924 19842 2 1238.666267 620.3409 T-complex protein 1 subunit alpha OS=Homo sapiens OX=9606 GN=TCP1 PE=1 SV=1 4.03 3457.4 - 5.37E+06 - - - -0.7339 - 2.805 0.483 - 583.2 1 2 0 -0.0009 10 0 0 0 4.86E+08 8.61E+08 - - - 5.4871 0.9999 221125_WJC_METTL3_EV_vs_WT_F02.19844.19844.2 1.35E-05 18-Sep K.EYPDFNFVGR.L "sp|Q96PU8|QKI_HUMAN,tr|F5H5U6|F5H5U6_HUMAN,tr|F5GYM3|F5GYM3_HUMAN,tr|F5GXS8|F5GXS8_HUMAN,tr|F5H8C8|F5H8C8_HUMAN" 5 1242.5669 2.01 18926 19844 2 1242.566096 622.2907 Protein quaking OS=Homo sapiens OX=9606 GN=QKI PE=1 SV=1 4.37 3457.5 - 4.67E+06 - - - -0.6768 - 1.702 0.568 - 277.2 1 2 0 -0.0008 10 0 0 0 6.20E+08 3.08E+08 - - - 4.7204 0.9998 221125_WJC_METTL3_EV_vs_WT_F02.19845.19845.2 2.51E-06 18-Dec R.IC[160.03]DDELILIK.N "sp|P17987|TCPA_HUMAN,tr|F5GZ03|F5GZ03_HUMAN,tr|F5H282|F5H282_HUMAN,tr|E7EQR6|E7EQR6_HUMAN,tr|E7ERF2|E7ERF2_HUMAN" 5 1230.653 0.57 18927 19845 2 1230.65363 616.3338 T-complex protein 1 subunit alpha OS=Homo sapiens OX=9606 GN=TCP1 PE=1 SV=1 4.03 3457.5 - 3.15E+06 - - - 0.5314 - 2.27 0.381 - 313.5 1 2 0 0.0007 10 0 0 0 4.84E+08 8.57E+08 - - - 4.1431 1 221125_WJC_METTL3_EV_vs_WT_F02.19847.19847.2 3.05E-08 20-Dec K.TLEEDEEELFK.M "sp|P43487|RANG_HUMAN,tr|C9JDM3|C9JDM3_HUMAN,tr|F6WQW2|F6WQW2_HUMAN,tr|C9JJ34|C9JJ34_HUMAN" 4 1380.6297 0.75 18929 19847 2 1380.626 691.3221 Ran-specific GTPase-activating protein OS=Homo sapiens OX=9606 GN=RANBP1 PE=1 SV=1 3.83 3457.7 - 2.16E+06 - - - -2.6488 - 2.517 0.616 - 347.3 1 2 0 -0.0037 11 0 0 0 1.10E+08 1.47E+08 - - - 6.0867 0.9994 221125_WJC_METTL3_EV_vs_WT_F02.19848.19848.2 3.49E-06 14/30 K.GPVFAPPYEPLPENVK[136.11].F sp|P11387|TOP1_HUMAN 1 1760.9229 0.9 18930 19848 2 1760.923791 881.4687 DNA topoisomerase 1 OS=Homo sapiens OX=9606 GN=TOP1 PE=1 SV=2 4.53 3457.8 - 1.64E+06 - - - 0.5213 - 2.624 0.204 - 518.4 1 2 0 0.0009 16 0 0 0 2.34E+07 2.58E+07 - - - 2.9192 1 221125_WJC_METTL3_EV_vs_WT_F02.19849.19849.3 1.57E-05 14/44 K.DAGTIAGLNVLR[166.11].L "sp|P11142|HSP7C_HUMAN,tr|E9PQQ4|E9PQQ4_HUMAN,tr|E9PKE3|E9PKE3_HUMAN,tr|E9PN89|E9PN89_HUMAN,tr|E9PLF4|E9PLF4_HUMAN,tr|E9PI65|E9PI65_HUMAN,tr|E9PK54|E9PK54_HUMAN,tr|E9PQK7|E9PQK7_HUMAN" 8 1208.6753 0.16 18931 19849 3 1208.67283 403.899 Heat shock cognate 71 kDa protein OS=Homo sapiens OX=9606 GN=HSPA8 PE=1 SV=1 5.84 3457.9 - 1.45E+06 - - - -2.0072 - 2.77 0.482 - 206.3 1 2 0 -0.0024 12 0 0 0 7.17E+07 4.54E+08 - - - 6.7372 1 221125_WJC_METTL3_EV_vs_WT_F02.19850.19850.2 4.36E-10 15/30 R.LVYLVENPGGYVAYSK[136.11].A "sp|P02786|TFR1_HUMAN,tr|G3V0E5|G3V0E5_HUMAN" 2 1778.9334 0.45 18932 19850 2 1778.934857 890.474 Transferrin receptor protein 1 OS=Homo sapiens OX=9606 GN=TFRC PE=1 SV=2 6 3458.1 - 948877 - - - 0.7977 - 2.746 0.622 - 739.4 1 2 0 0.0014 16 0 0 0 1.02E+07 2.25E+07 - - - 6.1181 0.9999 221125_WJC_METTL3_EV_vs_WT_F02.19852.19852.2 1.51E-06 14/26 K.ITEDSAVTTFEALK.A "sp|Q5VTB9|RN220_HUMAN,tr|Q5TDE8|Q5TDE8_HUMAN,tr|Q5TDE7|Q5TDE7_HUMAN" 3 1523.7719 1.84 18934 19852 2 1523.773128 762.8932 E3 ubiquitin-protein ligase RNF220 OS=Homo sapiens OX=9606 GN=RNF220 PE=1 SV=1 4.14 3458.3 - 736285 - - - 0.8026 - 2.876 0.484 - 724.8 1 2 0 0.0012 14 0 0 0 1.25E+07 6.80E+06 - - - 5.2664 0.9999 221125_WJC_METTL3_EV_vs_WT_F02.19855.19855.2 1.49E-06 16/30 K.VLAQNSGFDLQETLVK[136.11].L sp|P40227|TCPZ_HUMAN 1 1768.9451 0.48 18935 19855 2 1768.943285 885.4798 T-complex protein 1 subunit zeta OS=Homo sapiens OX=9606 GN=CCT6A PE=1 SV=3 4.37 3458.7 - 3.45E+06 - - - -1.0062 - 2.639 0.549 - 358.9 1 2 0 -0.0018 16 0 0 0 7.48E+08 1.56E+09 - - - 5.4811 0.9983 221125_WJC_METTL3_EV_vs_WT_F02.19856.19856.2 6.33E-06 14/24 K.VLATTFDPYLGGR[166.11].N "sp|O95757|HS74L_HUMAN,tr|D6RJ96|D6RJ96_HUMAN,tr|E9PDE8|E9PDE8_HUMAN" 3 1418.7433 0.11 18936 19856 2 1418.736964 710.3789 Heat shock 70 kDa protein 4L OS=Homo sapiens OX=9606 GN=HSPA4L PE=1 SV=3 5.81 3458.8 - 2.99E+06 - - - -4.4906 - 2.68 0.434 - 511.7 1 2 0 -0.0064 13 0 0 0 7.56E+06 7.09E+07 - - - 4.7747 0.9999 221125_WJC_METTL3_EV_vs_WT_F02.19857.19857.2 7.61E-05 22-Dec K.DAGTIAGLNVLR.L "sp|P11142|HSP7C_HUMAN,tr|E9PQQ4|E9PQQ4_HUMAN,tr|E9PKE3|E9PKE3_HUMAN,tr|E9PN89|E9PN89_HUMAN,tr|E9PLF4|E9PLF4_HUMAN,tr|E9PI65|E9PI65_HUMAN,tr|E9PK54|E9PK54_HUMAN,tr|E9PQK7|E9PQK7_HUMAN" 8 1198.667 0.16 18937 19857 2 1198.667177 600.3408 Heat shock cognate 71 kDa protein OS=Homo sapiens OX=9606 GN=HSPA8 PE=1 SV=1 5.84 3458.8 - 1.60E+07 - - - 0.1593 - 2.324 0.472 - 489.2 1 2 0 0.0002 12 0 0 0 3.35E+09 2.13E+10 - - - 4.746 0.9999 221125_WJC_METTL3_EV_vs_WT_F02.19858.19858.2 6.03E-05 18-Sep K.EYPDFNFVGR[166.11].L "sp|Q96PU8|QKI_HUMAN,tr|F5H5U6|F5H5U6_HUMAN,tr|F5GYM3|F5GYM3_HUMAN,tr|F5GXS8|F5GXS8_HUMAN,tr|F5H8C8|F5H8C8_HUMAN" 5 1252.5752 2.07 18938 19858 2 1252.574321 627.2949 Protein quaking OS=Homo sapiens OX=9606 GN=QKI PE=1 SV=1 4.37 3458.9 - 2.74E+06 - - - -0.7073 - 1.831 0.542 - 410.7 1 2 0 -0.0009 10 0 0 0 6.46E+08 3.12E+08 - - - 4.7323 1 221125_WJC_METTL3_EV_vs_WT_F02.19859.19859.3 1.23E-07 15/60 K.VLAQNSGFDLQETLVK[136.11].L sp|P40227|TCPZ_HUMAN 1 1768.9451 0.49 18939 19859 3 1768.947077 590.6556 T-complex protein 1 subunit zeta OS=Homo sapiens OX=9606 GN=CCT6A PE=1 SV=3 4.37 3459 - 1.95E+06 - - - 1.1374 - 3.073 0.435 - 326 1 2 0 0.002 16 0 0 0 2.59E+08 5.25E+08 - - - 6.2698 1 221125_WJC_METTL3_EV_vs_WT_F02.19860.19860.2 5.59E-09 13/22 K.NNALNQVVLWDK.L sp|P61009|SPCS3_HUMAN 1 1412.7412 1.09 18940 19860 2 1412.74129 707.3779 Signal peptidase complex subunit 3 OS=Homo sapiens OX=9606 GN=SPCS3 PE=1 SV=1 5.84 3459.1 - 1.66E+06 - - - 0.0545 - 2.739 0.604 - 653 1 2 0 0.0001 12 0 0 0 3.36E+07 3.08E+07 - - - 6.1533 0.9887 221125_WJC_METTL3_EV_vs_WT_F02.19862.19862.2 0.075 18-Aug R.KKTLVPALYK.V "sp|Q8IXS8|F126B_HUMAN,tr|C9JTA1|C9JTA1_HUMAN,tr|A0A804HIT6|A0A804HIT6_HUMAN,tr|F8W7X4|F8W7X4_HUMAN,tr|C9JNS4|C9JNS4_HUMAN,tr|C9J115|C9J115_HUMAN" 6 1159.7329 999 18942 19862 2 1159.730559 580.8737 Protein FAM126B OS=Homo sapiens OX=9606 GN=FAM126B PE=1 SV=1 10 3459.4 - 1.54E+06 - - - -2.0022 - 1.663 0.355 - 226.7 1 2 1 -0.0023 10 0 0 0 7.63E+07 0.00E+00 - - - 3.082 0.9999 221125_WJC_METTL3_EV_vs_WT_F02.19863.19863.2 2.78E-07 14/26 K.NVGLDIEAEVPAVK[136.11].D "sp|P50990|TCPQ_HUMAN,tr|H7C2U0|H7C2U0_HUMAN" 2 1460.7966 0.42 18943 19863 2 1460.795159 731.4056 T-complex protein 1 subunit theta OS=Homo sapiens OX=9606 GN=CCT8 PE=1 SV=4 4.14 3459.5 - 1.51E+06 - - - -0.9933 - 2.414 0.522 - 473.9 1 2 0 -0.0014 14 0 0 0 3.73E+08 8.90E+08 - - - 5.1076 1 221125_WJC_METTL3_EV_vs_WT_F02.19864.19864.2 1.02E-07 15/30 K.GPVFAPPYEPLPENVK.F sp|P11387|TOP1_HUMAN 1 1752.9087 0.8 18944 19864 2 1752.905414 877.4616 DNA topoisomerase 1 OS=Homo sapiens OX=9606 GN=TOP1 PE=1 SV=2 4.53 3459.6 - 1.51E+06 - - - -1.8592 - 2.836 0.587 - 510.3 1 2 0 -0.0033 16 0 0 0 2.69E+07 3.36E+07 - - - 5.9383 0.9999 221125_WJC_METTL3_EV_vs_WT_F02.19865.19865.2 3.23E-05 18-Oct R.GYAFITFC[160.03]GK[136.11].E "sp|O43390|HNRPR_HUMAN,tr|B4DT28|B4DT28_HUMAN,tr|A0A6Q8PH31|A0A6Q8PH31_HUMAN,tr|A0A6Q8PEX7|A0A6Q8PEX7_HUMAN,tr|A0A6Q8PH35|A0A6Q8PH35_HUMAN" 5 1170.5623 0.96 18945 19865 2 1170.563216 586.2884 Heterogeneous nuclear ribonucleoprotein R OS=Homo sapiens OX=9606 GN=HNRNPR PE=1 SV=1 8.2 3459.7 - 1.41E+06 - - - 0.768 - 2.024 0.531 - 431.7 1 2 0 0.0009 10 0 0 0 9.60E+07 9.98E+07 - - - 4.9308 0.9995 221125_WJC_METTL3_EV_vs_WT_F02.19871.19871.2 3.64E-07 14/22 K.ELWFSDDPNVTK[136.11].T "sp|O95831|AIFM1_HUMAN,tr|A0A6Q8PFW2|A0A6Q8PFW2_HUMAN,tr|A0A6Q8PFA7|A0A6Q8PFA7_HUMAN,tr|A0A6Q8PHJ9|A0A6Q8PHJ9_HUMAN,tr|A0A6Q8PFS4|A0A6Q8PFS4_HUMAN,tr|A0A7I2PK44|A0A7I2PK44_HUMAN,tr|A0A6Q8PF87|A0A6Q8PF87_HUMAN,tr|A0A6Q8PG15|A0A6Q8PG15_HUMAN,tr|A0A6Q8PFE1|A0A6Q8PFE1_HUMAN,tr|A0A7I2RLJ8|A0A7I2RLJ8_HUMAN,tr|A0A6Q8PFQ8|A0A6Q8PFQ8_HUMAN,tr|A0A6Q8PHC0|A0A6Q8PHC0_HUMAN,tr|A0A6Q8PFM5|A0A6Q8PFM5_HUMAN" 13 1457.6918 0.63 18949 19871 2 1457.687046 729.8532 "Apoptosis-inducing factor 1, mitochondrial OS=Homo sapiens OX=9606 GN=AIFM1 PE=1 SV=1" 4.03 3460.5 - 2.85E+06 - - - -3.2682 - 2.361 0.558 - 438.2 1 2 0 -0.0048 12 0 0 0 2.34E+07 3.70E+07 - - - 5.4213 1 221125_WJC_METTL3_EV_vs_WT_F02.19875.19875.3 1.16E-06 17/56 R.IAPPEAPVTGYMFGK.G "sp|P09874|PARP1_HUMAN,tr|A0A7I2V3E1|A0A7I2V3E1_HUMAN" 2 1576.796 1.26 18953 19875 3 1576.796223 526.6059 Poly [ADP-ribose] polymerase 1 OS=Homo sapiens OX=9606 GN=PARP1 PE=1 SV=4 6 3460.7 - 3.18E+06 - - - 0.1725 - 2.683 0.554 - 440.4 1 2 0 0.0003 15 0 0 0 7.40E+07 5.88E+07 - - - 7.2918 0.9999 221125_WJC_METTL3_EV_vs_WT_F02.19876.19876.2 4.78E-08 18-Nov R.GYAFITFC[160.03]GK.E "sp|O43390|HNRPR_HUMAN,tr|B4DT28|B4DT28_HUMAN,tr|A0A6Q8PH31|A0A6Q8PH31_HUMAN,tr|A0A6Q8PEX7|A0A6Q8PEX7_HUMAN,tr|A0A6Q8PH35|A0A6Q8PH35_HUMAN" 5 1162.5481 0.96 18954 19876 2 1162.546709 582.2813 Heterogeneous nuclear ribonucleoprotein R OS=Homo sapiens OX=9606 GN=HNRNPR PE=1 SV=1 8.2 3460.8 - 2.76E+06 - - - -1.2111 - 2.244 0.596 - 534.5 1 2 0 -0.0014 10 0 0 0 9.56E+07 9.98E+07 - - - 5.6987 0.999 221125_WJC_METTL3_EV_vs_WT_F02.19877.19877.2 0.000534 22-Dec K.ELWFSDDPNVTK.T "sp|O95831|AIFM1_HUMAN,tr|A0A6Q8PFW2|A0A6Q8PFW2_HUMAN,tr|A0A6Q8PFA7|A0A6Q8PFA7_HUMAN,tr|A0A6Q8PHJ9|A0A6Q8PHJ9_HUMAN,tr|A0A6Q8PFS4|A0A6Q8PFS4_HUMAN,tr|A0A7I2PK44|A0A7I2PK44_HUMAN,tr|A0A6Q8PF87|A0A6Q8PF87_HUMAN,tr|A0A6Q8PG15|A0A6Q8PG15_HUMAN,tr|A0A6Q8PFE1|A0A6Q8PFE1_HUMAN,tr|A0A7I2RLJ8|A0A7I2RLJ8_HUMAN,tr|A0A6Q8PFQ8|A0A6Q8PFQ8_HUMAN,tr|A0A6Q8PHC0|A0A6Q8PHC0_HUMAN,tr|A0A6Q8PFM5|A0A6Q8PFM5_HUMAN" 13 1449.6776 0.63 18955 19877 2 1449.673293 725.8461 "Apoptosis-inducing factor 1, mitochondrial OS=Homo sapiens OX=9606 GN=AIFM1 PE=1 SV=1" 4.03 3460.9 - 1.75E+06 - - - -2.9779 - 1.824 0.454 - 299.4 1 2 0 -0.0043 12 0 0 0 2.34E+07 3.70E+07 - - - 3.9743 0.9999 221125_WJC_METTL3_EV_vs_WT_F02.19878.19878.3 0.000843 13/44 K.DAGTIAGLNVLR.L "sp|P11142|HSP7C_HUMAN,tr|E9PQQ4|E9PQQ4_HUMAN,tr|E9PKE3|E9PKE3_HUMAN,tr|E9PN89|E9PN89_HUMAN,tr|E9PLF4|E9PLF4_HUMAN,tr|E9PI65|E9PI65_HUMAN,tr|E9PK54|E9PK54_HUMAN,tr|E9PQK7|E9PQK7_HUMAN" 8 1198.667 0.16 18956 19878 3 1198.6655 400.5629 Heat shock cognate 71 kDa protein OS=Homo sapiens OX=9606 GN=HSPA8 PE=1 SV=1 5.84 3461.1 - 1.35E+06 - - - -1.2397 - 2.459 0.393 - 190.1 1 2 0 -0.0015 12 0 0 0 7.17E+07 4.53E+08 - - - 5.4151 0.9966 221125_WJC_METTL3_EV_vs_WT_F02.19880.19880.2 0.0915 14-Jul K.IDHILDAL.- "sp|P04843|RPN1_HUMAN,tr|B7Z4L4|B7Z4L4_HUMAN" 2 908.4967 - 18958 19880 2 908.495645 455.2556 Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit 1 OS=Homo sapiens OX=9606 GN=RPN1 PE=1 SV=1 4.2 3461.3 - 1.18E+06 - - - -1.1976 - 1.376 0.214 - 123.4 1 2 0 -0.0011 8 0 0 0 - - - - - 1.5839 0.9997 221125_WJC_METTL3_EV_vs_WT_F02.19884.19884.2 0.000109 22-Sep K.NFSGAELEGLVR.A "sp|P46459|NSF_HUMAN,tr|I3L0N3|I3L0N3_HUMAN" 2 1290.6568 0.94 18961 19884 2 1290.655626 646.3357 Vesicle-fusing ATPase OS=Homo sapiens OX=9606 GN=NSF PE=1 SV=3 4.53 3461.8 - 495573 - - - -0.9212 - 1.982 0.394 - 237.8 1 2 0 -0.0012 12 0 0 0 8.61E+07 9.14E+07 - - - 3.7507 1 221125_WJC_METTL3_EV_vs_WT_F02.19886.19886.2 1.65E-06 13/20 K.AVENYLIQMAR[166.11].Y "sp|O14737|PDCD5_HUMAN,tr|K7EQA1|K7EQA1_HUMAN" 2 1316.6786 1.13 18962 19886 2 1316.676545 659.3466 Programmed cell death protein 5 OS=Homo sapiens OX=9606 GN=PDCD5 PE=1 SV=3 6.05 3462 - 2.06E+06 - - - -1.5813 - 2.682 0.575 - 770.8 1 2 0 -0.0021 11 0 0 0 5.85E+07 5.17E+07 - - - 5.9562 1 221125_WJC_METTL3_EV_vs_WT_F02.19888.19888.3 3.95E-07 14/60 K.VLAQNSGFDLQETLVK.L sp|P40227|TCPZ_HUMAN 1 1760.9309 0.49 18964 19888 3 1760.929434 587.9842 T-complex protein 1 subunit zeta OS=Homo sapiens OX=9606 GN=CCT6A PE=1 SV=3 4.37 3462.2 - 5.60E+06 - - - -0.8126 - 2.95 0.496 - 343.1 1 2 0 -0.0014 16 0 0 0 2.59E+08 5.25E+08 - - - 6.8453 0.9998 221125_WJC_METTL3_EV_vs_WT_F02.19890.19890.2 5.04E-05 14/20 K.AVENYLIQMAR.Y "sp|O14737|PDCD5_HUMAN,tr|K7EQA1|K7EQA1_HUMAN" 2 1306.6704 1.13 18966 19890 2 1306.66736 654.3425 Programmed cell death protein 5 OS=Homo sapiens OX=9606 GN=PDCD5 PE=1 SV=3 6.05 3462.4 - 2.04E+06 - - - -2.2936 - 2.585 0.542 - 802.4 1 2 0 -0.003 11 0 0 0 5.85E+07 5.17E+07 - - - 5.6125 0.9962 221125_WJC_METTL3_EV_vs_WT_F02.19891.19891.2 0.000241 24-Oct K.GAVWTVDEVEFQK.R "sp|Q9H334|FOXP1_HUMAN,tr|A0A3B3IRW5|A0A3B3IRW5_HUMAN,tr|G5E965|G5E965_HUMAN,tr|A0A3B3IRS5|A0A3B3IRS5_HUMAN,tr|A0A3B3IST0|A0A3B3IST0_HUMAN,tr|A0A3B3IUB6|A0A3B3IUB6_HUMAN,tr|H0Y882|H0Y882_HUMAN,tr|A0A3B3IT66|A0A3B3IT66_HUMAN,tr|A0A3B3IS87|A0A3B3IS87_HUMAN,tr|A0A0B4J2F3|A0A0B4J2F3_HUMAN,tr|A0A3B3IST6|A0A3B3IST6_HUMAN" 11 1506.7355 2.81 18967 19891 2 1506.729863 754.375 Forkhead box protein P1 OS=Homo sapiens OX=9606 GN=FOXP1 PE=1 SV=1 4.14 3462.5 - 1.67E+06 - - - -3.714 - 1.619 0.372 - 53.8 1 2 0 -0.0056 13 0 0 0 6.63E+07 2.36E+07 - - - 3.0234 0.9966 221125_WJC_METTL3_EV_vs_WT_F02.19908.19908.3 0.0157 Sep-36 R.IC[160.03]DDELILIK[136.11].N "sp|P17987|TCPA_HUMAN,tr|F5GZ03|F5GZ03_HUMAN,tr|F5H282|F5H282_HUMAN,tr|E7EQR6|E7EQR6_HUMAN,tr|E7ERF2|E7ERF2_HUMAN" 5 1238.6672 6.73 18980 19908 3 1238.66512 413.8963 T-complex protein 1 subunit alpha OS=Homo sapiens OX=9606 GN=TCP1 PE=1 SV=1 4.03 3464.4 - 682774 - - - -1.6598 - 1.581 0.254 - 80.1 1 2 0 -0.0021 10 0 0 0 5.60E+07 8.32E+06 - - - 2.709 0.9687 221125_WJC_METTL3_EV_vs_WT_F02.19912.19912.2 1.67 14-Jun K.DGIEFAFK[136.11].E "sp|Q8N3U4|STAG2_HUMAN,sp|Q8WVM7|STAG1_HUMAN,tr|Q68DW7|Q68DW7_HUMAN" 3 933.4687 0.34 18982 19912 2 933.468667 467.7416 Cohesin subunit SA-2 OS=Homo sapiens OX=9606 GN=STAG2 PE=1 SV=3 4.37 3464.9 - 1.04E+06 - - - -0.0707 - 1.128 0.091 - 72.5 3 2 0 -0.0001 8 0 0 0 6.63E+06 1.93E+07 - - - -0.1368 1 221125_WJC_METTL3_EV_vs_WT_F02.19913.19913.2 0.00365 13/22 R.NNIAMALEVTYR.E "sp|P24539|AT5F1_HUMAN,tr|Q5QNZ2|Q5QNZ2_HUMAN" 2 1393.7024 1.09 18983 19913 2 1393.697889 697.8585 "ATP synthase F(0) complex subunit B1, mitochondrial OS=Homo sapiens OX=9606 GN=ATP5PB PE=1 SV=2" 6 3465.1 - 1.53E+06 - - - -3.2259 - 2.801 0.556 - 567.2 1 2 0 -0.0045 12 0 0 0 2.81E+07 2.58E+07 - - - 5.8562 0.9794 221125_WJC_METTL3_EV_vs_WT_F02.19914.19914.2 0.0641 12-Jul R.QDFLPWK[136.11].S "sp|Q9BTC8|MTA3_HUMAN,sp|O94776|MTA2_HUMAN,sp|Q13330|MTA1_HUMAN,tr|E9PCS8|E9PCS8_HUMAN,tr|H0Y4T7|H0Y4T7_HUMAN,tr|E7EQY4|E7EQY4_HUMAN,tr|E7EV10|E7EV10_HUMAN,tr|F6RRE2|F6RRE2_HUMAN,tr|E7ESY4|E7ESY4_HUMAN" 9 940.4898 1.08 18984 19914 2 940.487164 471.2522 Metastasis-associated protein MTA3 OS=Homo sapiens OX=9606 GN=MTA3 PE=1 SV=2 5.84 3465.2 - 1.28E+06 - - - -2.806 - 1.158 0.209 - 163.8 1 2 0 -0.0026 7 0 0 0 3.37E+07 3.12E+07 - - - 1.0487 0.9997 221125_WJC_METTL3_EV_vs_WT_F02.19917.19917.2 9.34E-05 16-Jul R.YDLTVPFAR.Y "sp|P49590|SYHM_HUMAN,sp|P12081|HARS1_HUMAN,tr|A0A6Q8PF47|A0A6Q8PF47_HUMAN,tr|A0A2R8Y5P7|A0A2R8Y5P7_HUMAN,tr|A0A6Q8PF07|A0A6Q8PF07_HUMAN,tr|A0A2R8Y5E8|A0A2R8Y5E8_HUMAN,tr|A0A2R8Y6I1|A0A2R8Y6I1_HUMAN,tr|A0A6Q8PHA5|A0A6Q8PHA5_HUMAN,tr|E7ETE2|E7ETE2_HUMAN,tr|A0A2R8Y3N3|A0A2R8Y3N3_HUMAN,tr|A0A6Q8PFF2|A0A6Q8PFF2_HUMAN,tr|A0A2R8Y4X6|A0A2R8Y4X6_HUMAN,tr|A0A6Q8PFG9|A0A6Q8PFG9_HUMAN,tr|D6RJE6|D6RJE6_HUMAN,tr|A0A6Q8PFN6|A0A6Q8PFN6_HUMAN" 15 1080.5604 0.78 18985 19917 2 1080.56018 541.2875 "Histidine--tRNA ligase, mitochondrial OS=Homo sapiens OX=9606 GN=HARS2 PE=1 SV=1" 5.84 3465.6 - 967689 - - - -0.199 - 1.618 0.439 - 158.1 1 2 0 -0.0002 9 0 0 0 2.00E+09 2.57E+09 - - - 3.6755 0.9998 221125_WJC_METTL3_EV_vs_WT_F02.19920.19920.2 0.00159 18-Oct K.ANPDLPILIR.E sp|O43678|NDUA2_HUMAN 1 1120.6604 2.96 18988 19920 2 1120.660695 561.3375 NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 2 OS=Homo sapiens OX=9606 GN=NDUFA2 PE=1 SV=3 5.88 3465.9 - 2.46E+06 - - - 0.224 - 1.739 0.469 - 364.1 1 2 0 0.0003 10 0 0 0 4.41E+07 1.49E+07 - - - 4.0494 0.9998 221125_WJC_METTL3_EV_vs_WT_F02.19926.19926.2 1.26E-05 30-Dec K.AIEEGIPAFTC[160.03]EEYVK.S "sp|Q9Y2L1|RRP44_HUMAN,tr|F2Z2C0|F2Z2C0_HUMAN,tr|G3V1J5|G3V1J5_HUMAN" 3 1854.871 1.42 18992 19926 2 1854.868355 928.4428 Exosome complex exonuclease RRP44 OS=Homo sapiens OX=9606 GN=DIS3 PE=1 SV=2 4.09 3466.7 - 868513 - - - -1.4082 - 2.14 0.523 - 271.7 1 2 0 -0.0026 16 0 0 0 1.95E+07 1.38E+07 - - - 4.7735 0.9752 221125_WJC_METTL3_EV_vs_WT_F02.19927.19927.2 0.000104 20-Dec R.SALLVQLATAR.P "sp|Q9BSV6|SEN34_HUMAN,tr|A0A590UJ73|A0A590UJ73_HUMAN,tr|E7EQB3|E7EQB3_HUMAN,tr|A0A0G2JNK5|A0A0G2JNK5_HUMAN,tr|A0A0G2JNL0|A0A0G2JNL0_HUMAN,tr|A0A590UJW4|A0A590UJW4_HUMAN,tr|B0V3J0|B0V3J0_HUMAN" 7 1141.6819 2 18993 19927 2 1141.684816 571.8482 tRNA-splicing endonuclease subunit Sen34 OS=Homo sapiens OX=9606 GN=TSEN34 PE=1 SV=1 9.47 3466.8 - 1.50E+06 - - - 2.5471 - 2.645 0.42 - 410.2 1 1 0 0.0029 11 0 0 0 3.09E+07 1.55E+07 - - - 4.7735 0.9997 221125_WJC_METTL3_EV_vs_WT_F02.19928.19928.2 0.000123 13/24 K.GAVWTVDEVEFQK[136.11].R "sp|Q9H334|FOXP1_HUMAN,tr|A0A3B3IRW5|A0A3B3IRW5_HUMAN,tr|G5E965|G5E965_HUMAN,tr|A0A3B3IRS5|A0A3B3IRS5_HUMAN,tr|A0A3B3IST0|A0A3B3IST0_HUMAN,tr|A0A3B3IUB6|A0A3B3IUB6_HUMAN,tr|H0Y882|H0Y882_HUMAN,tr|A0A3B3IT66|A0A3B3IT66_HUMAN,tr|A0A3B3IS87|A0A3B3IS87_HUMAN,tr|A0A0B4J2F3|A0A0B4J2F3_HUMAN,tr|A0A3B3IST6|A0A3B3IST6_HUMAN" 11 1514.7497 2.81 18994 19928 2 1514.7529 758.3821 Forkhead box protein P1 OS=Homo sapiens OX=9606 GN=FOXP1 PE=1 SV=1 4.14 3466.9 - 1.25E+06 - - - 2.1396 - 2.479 0.461 - 496.1 1 2 0 0.0032 13 0 0 0 6.63E+07 2.36E+07 - - - 4.775 0.9995 221125_WJC_METTL3_EV_vs_WT_F02.19933.19933.2 0.0106 16-Sep K.LLQDFFNGK[136.11].E "sp|P54652|HSP72_HUMAN,sp|P11142|HSP7C_HUMAN,sp|P17066|HSP76_HUMAN,tr|E9PNE6|E9PNE6_HUMAN,tr|A8K7Q2|A8K7Q2_HUMAN,tr|E9PKE3|E9PKE3_HUMAN,tr|E9PN89|E9PN89_HUMAN" 7 1088.5746 0.17 18997 19933 2 1088.573705 545.2946 Heat shock-related 70 kDa protein 2 OS=Homo sapiens OX=9606 GN=HSPA2 PE=1 SV=1 5.84 3467.6 - 8.93E+06 - - - -0.8176 - 1.678 0.352 - 216.9 1 2 0 -0.0009 9 0 0 0 2.00E+09 1.20E+10 - - - 3.138 0.9999 221125_WJC_METTL3_EV_vs_WT_F02.19936.19936.2 0.00663 14/26 K.LLDVTGGLGTDELR[166.11].L "sp|Q9Y4W2|LAS1L_HUMAN,tr|A0A7I2V3R6|A0A7I2V3R6_HUMAN,tr|A0A7I2V3Q3|A0A7I2V3Q3_HUMAN,tr|A0A7I2V4V0|A0A7I2V4V0_HUMAN,tr|A0A7I2V5R7|A0A7I2V5R7_HUMAN,tr|A0A7I2V653|A0A7I2V653_HUMAN,tr|A0A7I2YQI7|A0A7I2YQI7_HUMAN" 7 1467.7808 0.65 19000 19936 2 1467.781088 734.8977 Ribosomal biogenesis protein LAS1L OS=Homo sapiens OX=9606 GN=LAS1L PE=1 SV=2 4.03 3468 - 1.73E+06 - - - 0.1669 - 2.744 0.412 - 760.8 1 2 0 0.0002 14 0 0 0 1.23E+07 1.89E+07 - - - 4.617 0.9999 221125_WJC_METTL3_EV_vs_WT_F02.19938.19938.2 1.69E-07 13/26 K.LYTLVLTDPDAPSR.K sp|P30086|PEBP1_HUMAN 1 1559.8195 1.5 19002 19938 2 1559.821099 780.917 Phosphatidylethanolamine-binding protein 1 OS=Homo sapiens OX=9606 GN=PEBP1 PE=1 SV=3 4.21 3468.2 - 1.01E+06 - - - 1.0104 - 2.413 0.572 - 524 1 2 0 0.0016 14 0 0 0 1.13E+07 7.55E+06 - - - 5.4758 0.9997 221125_WJC_METTL3_EV_vs_WT_F02.19940.19940.2 5.90E-05 30-Oct K.AIEEGIPAFTC[160.03]EEYVK[136.11].S "sp|Q9Y2L1|RRP44_HUMAN,tr|F2Z2C0|F2Z2C0_HUMAN,tr|G3V1J5|G3V1J5_HUMAN" 3 1862.8852 1.42 19004 19940 2 1862.884852 932.4499 Exosome complex exonuclease RRP44 OS=Homo sapiens OX=9606 GN=DIS3 PE=1 SV=2 4.09 3468.5 - 752442 - - - -0.1691 - 1.96 0.41 - 131.8 1 2 0 -0.0003 16 0 0 0 1.95E+07 1.38E+07 - - - 3.7236 0.9998 221125_WJC_METTL3_EV_vs_WT_F02.19941.19941.2 8.49E-09 13/26 K.LYTLVLTDPDAPSR[166.11].K sp|P30086|PEBP1_HUMAN 1 1569.8278 1.5 19005 19941 2 1569.825102 785.9212 Phosphatidylethanolamine-binding protein 1 OS=Homo sapiens OX=9606 GN=PEBP1 PE=1 SV=3 4.21 3468.6 - 616097 - - - -1.7142 - 2.575 0.495 - 475.1 1 2 0 -0.0027 14 0 0 0 1.13E+07 7.55E+06 - - - 5.0698 0.9885 221125_WJC_METTL3_EV_vs_WT_F02.19943.19943.2 1.72E-06 24-Dec R.LSESVLSPPC[160.03]FVR.N "sp|Q93009|UBP7_HUMAN,tr|H3BRA2|H3BRA2_HUMAN,tr|A0A669KBL1|A0A669KBL1_HUMAN,tr|H3BUV0|H3BUV0_HUMAN,tr|F5H2X1|F5H2X1_HUMAN,tr|H3BQD1|H3BQD1_HUMAN,tr|H3BTM1|H3BTM1_HUMAN" 7 1489.7599 0.9 19006 19943 2 1489.749069 745.8872 Ubiquitin carboxyl-terminal hydrolase 7 OS=Homo sapiens OX=9606 GN=USP7 PE=1 SV=2 5.99 3468.8 - 883047 - - - -7.2703 - 2.55 0.445 - 487.7 1 2 0 -0.0108 13 0 0 0 8.82E+06 9.81E+06 - - - 4.7269 0.9917 221125_WJC_METTL3_EV_vs_WT_F02.19946.19946.2 8.93E-05 18-Oct S.SFDLDYDFQR.D "sp|P07910|HNRPC_HUMAN,tr|G3V251|G3V251_HUMAN,tr|B4DY08|B4DY08_HUMAN,tr|G3V575|G3V575_HUMAN,tr|G3V5V7|G3V5V7_HUMAN,tr|G3V3K6|G3V3K6_HUMAN,tr|B2R5W2|B2R5W2_HUMAN,tr|G3V4C1|G3V4C1_HUMAN,tr|G3V576|G3V576_HUMAN,tr|G3V2D6|G3V2D6_HUMAN,tr|G3V5X6|G3V5X6_HUMAN,tr|G3V4W0|G3V4W0_HUMAN,tr|G3V555|G3V555_HUMAN,tr|G3V2Q1|G3V2Q1_HUMAN" 14 1304.5673 1.59 19008 19946 2 1304.565688 653.2909 Heterogeneous nuclear ribonucleoproteins C1\C2 OS=Homo sapiens OX=9606 GN=HNRNPC PE=1 SV=4 3.93 3469.1 - 3.68E+06 - - - -1.2594 - 2.145 0.542 - 367.8 1 1 0 -0.0016 10 0 0 0 2.68E+07 1.68E+07 - - - 5.1739 0.9907 221125_WJC_METTL3_EV_vs_WT_F02.19948.19948.2 0.00194 18-Oct S.SFDLDYDFQR[166.11].D "sp|P07910|HNRPC_HUMAN,tr|G3V251|G3V251_HUMAN,tr|B4DY08|B4DY08_HUMAN,tr|G3V575|G3V575_HUMAN,tr|G3V5V7|G3V5V7_HUMAN,tr|G3V3K6|G3V3K6_HUMAN,tr|B2R5W2|B2R5W2_HUMAN,tr|G3V4C1|G3V4C1_HUMAN,tr|G3V576|G3V576_HUMAN,tr|G3V2D6|G3V2D6_HUMAN,tr|G3V5X6|G3V5X6_HUMAN,tr|G3V4W0|G3V4W0_HUMAN,tr|G3V555|G3V555_HUMAN,tr|G3V2Q1|G3V2Q1_HUMAN" 14 1314.5756 1.59 19010 19948 2 1314.573719 658.2951 Heterogeneous nuclear ribonucleoproteins C1\C2 OS=Homo sapiens OX=9606 GN=HNRNPC PE=1 SV=4 3.93 3469.3 - 2.06E+06 - - - -1.4316 - 2.123 0.54 - 359.9 1 1 0 -0.0019 10 0 0 0 2.68E+07 1.68E+07 - - - 5.1302 0.9997 221125_WJC_METTL3_EV_vs_WT_F02.19950.19950.2 0.00808 18-Oct K.ANPDLPILIR[166.11].E sp|O43678|NDUA2_HUMAN 1 1130.6687 2.96 19012 19950 2 1130.669245 566.3416 NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 2 OS=Homo sapiens OX=9606 GN=NDUFA2 PE=1 SV=3 5.88 3469.5 - 1.34E+06 - - - 0.4696 - 1.818 0.394 - 325.3 1 2 0 0.0005 10 0 0 0 4.41E+07 1.49E+07 - - - 3.6194 0.9997 221125_WJC_METTL3_EV_vs_WT_F02.19951.19951.2 4.43E-05 26-Dec K.YTLLLGQDENSVIK[136.11].S "sp|Q9H8H0|NOL11_HUMAN,tr|J3QR28|J3QR28_HUMAN" 2 1599.8599 1.42 19013 19951 2 1599.863595 800.9372 Nucleolar protein 11 OS=Homo sapiens OX=9606 GN=NOL11 PE=1 SV=1 4.37 3469.6 - 1.13E+06 - - - 2.2858 - 2.343 0.532 - 373.7 1 2 0 0.0037 14 0 0 0 1.56E+07 1.09E+07 - - - 5.1058 0.9998 221125_WJC_METTL3_EV_vs_WT_F02.19954.19954.2 4.32E-08 30-Dec K.LNPADAPNPVVFVATK.D sp|O94776|MTA2_HUMAN 1 1651.8934 0.88 19016 19954 2 1651.895803 826.954 Metastasis-associated protein MTA2 OS=Homo sapiens OX=9606 GN=MTA2 PE=1 SV=1 5.84 3470 - 659888 - - - 1.4807 - 2.169 0.52 - 292.2 1 2 0 0.0024 16 0 0 0 1.40E+07 1.58E+07 - - - 4.7845 1 221125_WJC_METTL3_EV_vs_WT_F02.19955.19955.2 1.18E-07 16/32 R.LFQTAFPAPYGPSPASR[166.11].Y sp|Q9Y6J9|TAF6L_HUMAN 1 1815.9183 1.32 19017 19955 2 1815.9175 908.9664 TAF6-like RNA polymerase II p300\CBP-associated factor-associated factor 65 kDa subunit 6L OS=Homo sapiens OX=9606 GN=TAF6L PE=1 SV=1 8.75 3470.1 - 657348 - - - -0.4626 - 3.271 0.588 - 443.5 1 2 0 -0.0008 17 0 0 0 2.11E+07 1.59E+07 - - - 6.2973 1 221125_WJC_METTL3_EV_vs_WT_F02.19960.19960.2 9.85E-05 20-Dec R.VSVELTNSLFK.H sp|P14923|PLAK_HUMAN 1 1235.6762 24.36 19021 19960 2 1235.67497 618.8454 Junction plakoglobin OS=Homo sapiens OX=9606 GN=JUP PE=1 SV=3 5.97 3470.8 - 3.23E+07 - - - -0.9582 - 2.573 0.559 - 670.1 1 2 0 -0.0012 11 0 0 0 2.33E+08 9.56E+06 - - - 5.726 0.9999 221125_WJC_METTL3_EV_vs_WT_F02.19962.19962.2 0.000132 16/24 R.AITGASLADIMAK[136.11].R "sp|P83731|RL24_HUMAN,tr|C9JNW5|C9JNW5_HUMAN,tr|C9JXB8|C9JXB8_HUMAN" 3 1268.689 0.95 19023 19962 2 1268.688879 635.3518 60S ribosomal protein L24 OS=Homo sapiens OX=9606 GN=RPL24 PE=1 SV=1 5.88 3470.9 - 3.10E+06 - - - -0.0741 - 3.09 0.455 - 707.2 1 2 0 -0.0001 13 0 0 0 1.83E+08 1.93E+08 - - - 5.2971 0.9677 221125_WJC_METTL3_EV_vs_WT_F02.19963.19963.2 2.29 12-Aug R.SLSDLFR[166.11].R "sp|O75410|TACC1_HUMAN,tr|E7EVI4|E7EVI4_HUMAN,tr|B4E3H6|B4E3H6_HUMAN,tr|H0YAY0|H0YAY0_HUMAN,tr|H0YBT8|H0YBT8_HUMAN,tr|E7ET87|E7ET87_HUMAN" 6 846.4475 1.1 19024 19963 2 846.44687 424.231 Transforming acidic coiled-coil-containing protein 1 OS=Homo sapiens OX=9606 GN=TACC1 PE=1 SV=2 5.55 3471 - 2.22E+06 - - - -0.7301 - 1.228 0.028 - 205.5 1 2 0 -0.0006 7 0 0 0 6.62E+07 6.04E+07 - - - -0.1016 0.9997 221125_WJC_METTL3_EV_vs_WT_F02.19964.19964.2 7.26E-07 26-Dec K.LLDVTGGLGTDELR.L "sp|Q9Y4W2|LAS1L_HUMAN,tr|A0A7I2V3R6|A0A7I2V3R6_HUMAN,tr|A0A7I2V3Q3|A0A7I2V3Q3_HUMAN,tr|A0A7I2V4V0|A0A7I2V4V0_HUMAN,tr|A0A7I2V5R7|A0A7I2V5R7_HUMAN,tr|A0A7I2V653|A0A7I2V653_HUMAN,tr|A0A7I2YQI7|A0A7I2YQI7_HUMAN" 7 1457.7726 0.65 19025 19964 2 1457.775684 729.8936 Ribosomal biogenesis protein LAS1L OS=Homo sapiens OX=9606 GN=LAS1L PE=1 SV=2 4.03 3471 - 1.96E+06 - - - 2.1341 - 2.444 0.518 - 516.3 1 2 0 0.0031 14 0 0 0 1.23E+07 1.89E+07 - - - 5.1085 0.8794 221125_WJC_METTL3_EV_vs_WT_F02.19965.19965.2 0.223 May-32 R.ASSGGGAGGAAGYAPVK.Y sp|P25067|CO8A2_HUMAN 1 1376.6684 0.86 19026 19965 2 1376.665254 689.3415 Collagen alpha-2(VIII) chain OS=Homo sapiens OX=9606 GN=COL8A2 PE=1 SV=2 8.63 3471.1 - 1.80E+06 - - - -2.3157 - 1.156 0.107 - 32.2 22 2 0 -0.0032 17 0 0 0 6.07E+07 7.08E+07 - - - -0.413 0.9998 221125_WJC_METTL3_EV_vs_WT_F02.19966.19966.2 1.70E-05 18-Sep R.IYGISFPDPK.M sp|P26639|SYTC_HUMAN 1 1135.5914 1.01 19027 19966 2 1135.591513 568.803 "Threonine--tRNA ligase 1, cytoplasmic OS=Homo sapiens OX=9606 GN=TARS1 PE=1 SV=3" 5.83 3471.2 - 1.44E+06 - - - 0.1339 - 2.056 0.453 - 206.7 1 2 0 0.0002 10 0 0 0 2.13E+07 2.10E+07 - - - 4.3987 0.9996 221125_WJC_METTL3_EV_vs_WT_F02.19967.19967.2 0.000389 16-Nov R.TLADIIMEK[136.11].L "sp|Q13895|BYST_HUMAN,tr|H7BY94|H7BY94_HUMAN" 2 1040.5667 0.4 19028 19967 2 1040.566195 521.2906 Bystin OS=Homo sapiens OX=9606 GN=BYSL PE=1 SV=3 4.37 3471.4 - 1.39E+06 - - - -0.517 - 1.89 0.331 - 287 1 2 0 -0.0005 9 0 0 0 7.80E+06 1.96E+07 - - - 3.3272 1 221125_WJC_METTL3_EV_vs_WT_F02.19973.19973.2 4.63E-08 17/32 R.LFQTAFPAPYGPSPASR.Y sp|Q9Y6J9|TAF6L_HUMAN 1 1805.9101 1.32 19034 19973 2 1805.911969 903.9623 TAF6-like RNA polymerase II p300\CBP-associated factor-associated factor 65 kDa subunit 6L OS=Homo sapiens OX=9606 GN=TAF6L PE=1 SV=1 8.75 3472.1 - 1.05E+06 - - - 1.0515 - 3.277 0.583 - 521.4 1 2 0 0.0019 17 0 0 0 2.11E+07 1.59E+07 - - - 6.2646 0.9994 221125_WJC_METTL3_EV_vs_WT_F02.19976.19976.2 0.00106 24-Sep K.LAFYPNQDGDILR.D "sp|Q14C86|GAPD1_HUMAN,tr|F8W9S7|F8W9S7_HUMAN" 2 1520.7623 0.16 19037 19976 2 1520.765693 761.3884 GTPase-activating protein and VPS9 domain-containing protein 1 OS=Homo sapiens OX=9606 GN=GAPVD1 PE=1 SV=2 4.21 3472.5 - 649075 - - - 2.2028 - 2.148 0.381 - 218.7 1 2 0 0.0034 13 0 0 0 6.20E+06 3.92E+07 - - - 3.8162 0.9673 221125_WJC_METTL3_EV_vs_WT_F02.19979.19979.2 1.33 12-May K.SFSDLFK[136.11].R "sp|Q9Y6A5|TACC3_HUMAN,tr|A0A087WUE2|A0A087WUE2_HUMAN,tr|A0A494BZT8|A0A494BZT8_HUMAN" 3 850.4316 1.25 19040 19979 2 850.433035 426.2231 Transforming acidic coiled-coil-containing protein 3 OS=Homo sapiens OX=9606 GN=TACC3 PE=1 SV=1 5.55 3472.9 - 478488 - - - 1.6639 - 1.038 0.165 - 77 2 2 0 0.0014 7 0 0 0 7.51E+06 5.99E+06 - - - 0.2429 0.945 221125_WJC_METTL3_EV_vs_WT_F02.19982.19982.2 0.684 Apr-32 R.ASSGGGAGGAAGYAPVK[136.11].Y sp|P25067|CO8A2_HUMAN 1 1384.6826 0.9 19042 19982 2 1384.68155 693.3486 Collagen alpha-2(VIII) chain OS=Homo sapiens OX=9606 GN=COL8A2 PE=1 SV=2 8.63 3473.2 - 5.14E+06 - - - -0.7886 - 1.01 0.156 - 19.8 29 2 0 -0.0011 17 0 0 0 6.42E+07 7.11E+07 - - - -0.4359 1 221125_WJC_METTL3_EV_vs_WT_F02.19984.19984.2 2.15E-05 14/24 R.AITGASLADIMAK.R "sp|P83731|RL24_HUMAN,tr|C9JNW5|C9JNW5_HUMAN,tr|C9JXB8|C9JXB8_HUMAN" 3 1260.6748 0.88 19044 19984 2 1260.6734 631.3447 60S ribosomal protein L24 OS=Homo sapiens OX=9606 GN=RPL24 PE=1 SV=1 5.88 3473.2 - 9.91E+06 - - - -1.0891 - 2.865 0.547 - 513.5 1 2 0 -0.0014 13 0 0 0 1.67E+08 1.90E+08 - - - 5.7822 0.9999 221125_WJC_METTL3_EV_vs_WT_F02.19986.19986.2 0.000893 13/22 K.LFVTNDAATILR.E "sp|P50990|TCPQ_HUMAN,tr|H7C4C8|H7C4C8_HUMAN" 2 1332.7402 0.48 19046 19986 2 1332.738778 667.3774 T-complex protein 1 subunit theta OS=Homo sapiens OX=9606 GN=CCT8 PE=1 SV=4 5.84 3473.3 - 4.05E+06 - - - -1.0302 - 2.386 0.473 - 660.6 1 2 0 -0.0014 12 0 0 0 8.47E+07 1.75E+08 - - - 4.8223 0.9994 221125_WJC_METTL3_EV_vs_WT_F02.19987.19987.2 0.000593 18-Aug R.IYGISFPDPK[136.11].M sp|P26639|SYTC_HUMAN 1 1143.6056 0.6 19047 19987 2 1143.604008 572.8101 "Threonine--tRNA ligase 1, cytoplasmic OS=Homo sapiens OX=9606 GN=TARS1 PE=1 SV=3" 5.83 3473.4 - 3.40E+06 - - - -1.358 - 1.678 0.37 - 155.5 1 2 0 -0.0016 10 0 0 0 1.07E+07 1.78E+07 - - - 3.2181 0.9997 221125_WJC_METTL3_EV_vs_WT_F02.19988.19988.2 0.00115 14-Sep K.WDLSELPK.F "sp|Q92841|DDX17_HUMAN,tr|A0A5H1ZRQ2|A0A5H1ZRQ2_HUMAN,tr|A0A1X7SBZ2|A0A1X7SBZ2_HUMAN" 3 986.5073 0.97 19048 19988 2 986.507031 494.2609 Probable ATP-dependent RNA helicase DDX17 OS=Homo sapiens OX=9606 GN=DDX17 PE=1 SV=2 4.37 3473.4 - 3.10E+06 - - - -0.2696 - 1.653 0.391 - 345.5 1 2 0 -0.0003 8 0 0 0 1.63E+08 1.69E+08 - - - 3.4446 0.9996 221125_WJC_METTL3_EV_vs_WT_F02.19990.19990.2 0.00431 14-Sep K.WDLSELPK[136.11].F "sp|Q92841|DDX17_HUMAN,tr|A0A5H1ZRQ2|A0A5H1ZRQ2_HUMAN,tr|A0A1X7SBZ2|A0A1X7SBZ2_HUMAN" 3 994.5215 0.96 19050 19990 2 994.520956 498.268 Probable ATP-dependent RNA helicase DDX17 OS=Homo sapiens OX=9606 GN=DDX17 PE=1 SV=2 4.37 3473.6 - 3.00E+06 - - - -0.544 - 1.663 0.38 - 331.2 1 2 0 -0.0005 8 0 0 0 1.63E+08 1.70E+08 - - - 3.3815 0.992 221125_WJC_METTL3_EV_vs_WT_F02.19992.19992.2 0.000556 18-Sep R.LTAEDLFEAR[166.11].L "sp|Q15149|PLEC_HUMAN,tr|H0YDN1|H0YDN1_HUMAN" 2 1173.5905 0.07 19052 19992 2 1173.583727 587.8025 Plectin OS=Homo sapiens OX=9606 GN=PLEC PE=1 SV=3 4.14 3473.7 - 1.50E+06 - - - -5.7908 - 2.155 0.361 - 240.8 1 2 0 -0.0068 10 0 0 0 6.83E+06 1.02E+08 - - - 3.8483 0.9449 221125_WJC_METTL3_EV_vs_WT_F02.19993.19993.2 0.000769 12-Aug L.QDFFNGK[136.11].E "sp|P54652|HSP72_HUMAN,sp|P11142|HSP7C_HUMAN,sp|P17066|HSP76_HUMAN,tr|E9PNE6|E9PNE6_HUMAN,tr|A8K7Q2|A8K7Q2_HUMAN,tr|E9PKE3|E9PKE3_HUMAN,tr|E9PN89|E9PN89_HUMAN" 7 862.4065 0.12 19053 19993 2 862.405642 432.2105 Heat shock-related 70 kDa protein 2 OS=Homo sapiens OX=9606 GN=HSPA2 PE=1 SV=1 5.84 3473.8 - 1.10E+06 - - - -0.9566 - 1.515 0.296 - 202.6 1 1 0 -0.0008 7 0 0 0 2.25E+06 1.93E+07 - - - 2.5433 1 221125_WJC_METTL3_EV_vs_WT_F02.19995.19995.2 7.29E-05 22-Dec K.LSTDDLNSLIAH.A "sp|Q16891|MIC60_HUMAN,tr|B9A067|B9A067_HUMAN,tr|C9J406|C9J406_HUMAN,tr|H7C463|H7C463_HUMAN" 4 1297.6514 - 19055 19995 2 1297.652347 649.833 MICOS complex subunit MIC60 OS=Homo sapiens OX=9606 GN=IMMT PE=1 SV=1 4.2 3474 - 876488 - - - 0.7336 - 2.657 0.584 - 542.8 1 1 0 0.001 12 0 0 0 - - - - - 5.9253 0.9999 221125_WJC_METTL3_EV_vs_WT_F02.20000.20000.2 0.00157 18-Oct K.FAAQELIEVK[136.11].R "sp|Q86U44|MTA70_HUMAN,tr|F5H6D8|F5H6D8_HUMAN,tr|H0YFV6|H0YFV6_HUMAN,tr|B4DTN4|B4DTN4_HUMAN" 4 1154.6427 0.02 19059 20000 2 1154.642154 578.3286 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 4.53 3474.5 - 5.14E+06 - - - -0.4512 - 2.069 0.475 - 271.3 1 2 0 -0.0005 10 0 0 0 1.54E+07 7.41E+08 - - - 4.5786 0.9998 221125_WJC_METTL3_EV_vs_WT_F02.20001.20001.2 1.58E-05 15/28 R.FFVADTANEALEAAK.R "sp|Q96I99|SUCB2_HUMAN,tr|E9PDQ8|E9PDQ8_HUMAN" 2 1595.7831 1.26 19060 20001 2 1595.780884 798.8988 "Succinate--CoA ligase [GDP-forming] subunit beta, mitochondrial OS=Homo sapiens OX=9606 GN=SUCLG2 PE=1 SV=2" 4.14 3474.6 - 3.62E+06 - - - -1.4125 - 2.186 0.527 - 544.7 1 2 0 -0.0023 15 0 0 0 1.30E+07 1.03E+07 - - - 4.8555 0.9984 221125_WJC_METTL3_EV_vs_WT_F02.20003.20003.3 3.01E-06 18/52 Q.LDGIHLLDPDVVAR[166.11].F sp|Q86U44|MTA70_HUMAN 1 1541.8441 0.02 19062 20003 3 1541.844919 514.9553 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 4.41 3474.6 - 5.52E+06 - - - 0.5234 - 3.428 0.511 - 557.6 1 1 0 0.0008 14 0 0 0 7.34E+07 3.93E+09 - - - 7.5109 0.9997 221125_WJC_METTL3_EV_vs_WT_F02.20004.20004.2 0.000148 20-Sep K.VQYPDYYAIIK.E "sp|Q86U86|PB1_HUMAN,tr|H0Y5B5|H0Y5B5_HUMAN,tr|E7EVG2|E7EVG2_HUMAN,tr|C9JPI5|C9JPI5_HUMAN" 4 1371.7075 6.35 19063 20004 2 1371.705456 686.861 Protein polybromo-1 OS=Homo sapiens OX=9606 GN=PBRM1 PE=1 SV=1 5.8 3474.7 - 2.69E+06 - - - -1.4566 - 1.795 0.459 - 223.6 1 2 0 -0.002 11 0 0 0 2.38E+08 3.75E+07 - - - 4.0131 0.9981 221125_WJC_METTL3_EV_vs_WT_F02.20005.20005.2 0.00348 16-Sep R.YLDVSILGK[136.11].F sp|Q86U44|MTA70_HUMAN 1 1014.5841 0.08 19064 20005 2 1014.580482 508.2993 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 5.83 3474.8 - 2.14E+06 - - - -3.564 - 1.622 0.438 - 190 1 2 0 -0.0036 9 0 0 0 1.69E+06 2.01E+07 - - - 3.6742 0.9853 221125_WJC_METTL3_EV_vs_WT_F02.20007.20007.2 0.000269 14-Oct L.LQDFFNGK[136.11].E "sp|P54652|HSP72_HUMAN,sp|P11142|HSP7C_HUMAN,sp|P17066|HSP76_HUMAN,tr|E9PNE6|E9PNE6_HUMAN,tr|A8K7Q2|A8K7Q2_HUMAN,tr|E9PKE3|E9PKE3_HUMAN,tr|E9PN89|E9PN89_HUMAN" 7 975.4905 0.02 19066 20007 2 975.491146 488.7525 Heat shock-related 70 kDa protein 2 OS=Homo sapiens OX=9606 GN=HSPA2 PE=1 SV=1 5.84 3475 - 1.67E+06 - - - 0.6305 - 1.844 0.417 - 264.1 1 1 0 0.0006 8 0 0 0 7.58E+06 4.26E+08 - - - 3.9663 1 221125_WJC_METTL3_EV_vs_WT_F02.20011.20011.2 2.88E-05 16/28 K.ITNLTQQLEQASIVK.K sp|P15924|DESP_HUMAN 1 1684.936 999 19070 20011 2 1684.935738 843.4753 Desmoplakin OS=Homo sapiens OX=9606 GN=DSP PE=1 SV=3 6 3475.5 - 932879 - - - -0.1258 - 3.6 0.531 - 1020.7 1 2 0 -0.0002 15 0 0 0 8.21E+06 0.00E+00 - - - 6.1121 0.9999 221125_WJC_METTL3_EV_vs_WT_F02.20012.20012.3 5.19E-06 Nov-44 K.LFVTNDAATILR[166.11].E "sp|P50990|TCPQ_HUMAN,tr|H7C4C8|H7C4C8_HUMAN" 2 1342.7484 0.26 19071 20012 3 1342.748185 448.5901 T-complex protein 1 subunit theta OS=Homo sapiens OX=9606 GN=CCT8 PE=1 SV=4 5.84 3475.6 - 714937 - - - -0.1758 - 2.243 0.437 - 166.7 1 2 0 -0.0002 12 0 0 0 1.62E+06 6.33E+06 - - - 5.6512 0.9998 221125_WJC_METTL3_EV_vs_WT_F02.20014.20014.2 3.03E-05 18-Oct R.LTAEDLFEAR.L "sp|Q15149|PLEC_HUMAN,tr|H0YDN1|H0YDN1_HUMAN" 2 1163.5823 0.32 19072 20014 2 1163.582896 582.7984 Plectin OS=Homo sapiens OX=9606 GN=PLEC PE=1 SV=3 4.14 3475.8 - 2.48E+06 - - - 0.5526 - 2.233 0.442 - 354.7 1 2 0 0.0006 10 0 0 0 2.67E+07 8.32E+07 - - - 4.5478 0.9993 221125_WJC_METTL3_EV_vs_WT_F02.20016.20016.2 0.0133 16-Oct R.LIDFLEC[160.03]GK[136.11].T "sp|P17844|DDX5_HUMAN,tr|A0A7I2V5F5|A0A7I2V5F5_HUMAN,tr|J3KRZ1|J3KRZ1_HUMAN,tr|J3QSF1|J3QSF1_HUMAN,tr|A0A7I2V507|A0A7I2V507_HUMAN,tr|J3KTA4|J3KTA4_HUMAN,tr|A0A0G2JLI4|A0A0G2JLI4_HUMAN,tr|A0A7I2V2S0|A0A7I2V2S0_HUMAN" 8 1101.562 1.4 19073 20016 2 1101.559409 551.7883 Probable ATP-dependent RNA helicase DDX5 OS=Homo sapiens OX=9606 GN=DDX5 PE=1 SV=1 4.37 3476 - 1.54E+07 - - - -2.3358 - 1.856 0.397 - 269.7 1 2 0 -0.0026 9 0 0 0 5.67E+08 4.05E+08 - - - 3.7616 0.9999 221125_WJC_METTL3_EV_vs_WT_F02.20017.20017.2 1.31E-05 13/24 K.EVGEAFTILSDPK.K "sp|Q99615|DNJC7_HUMAN,tr|A0A6I8PRZ0|A0A6I8PRZ0_HUMAN,tr|A0A6I8PIK4|A0A6I8PIK4_HUMAN,tr|A0A6I8PS32|A0A6I8PS32_HUMAN,tr|A0A6I8PUD4|A0A6I8PUD4_HUMAN,tr|K7ER44|K7ER44_HUMAN,tr|A0A6I8PU73|A0A6I8PU73_HUMAN" 7 1404.7137 0.85 19074 20017 2 1404.712401 703.3641 DnaJ homolog subfamily C member 7 OS=Homo sapiens OX=9606 GN=DNAJC7 PE=1 SV=2 4.14 3476.1 - 2.44E+06 - - - -0.897 - 2.488 0.466 - 464.6 1 2 0 -0.0013 13 0 0 0 5.31E+07 6.22E+07 - - - 4.8218 0.9998 221125_WJC_METTL3_EV_vs_WT_F02.20018.20018.2 0.000273 20-Nov K.QNLFLGSLTSR.L "sp|Q3ZCQ8|TIM50_HUMAN,tr|M0R0C3|M0R0C3_HUMAN,tr|M0R2F8|M0R2F8_HUMAN" 3 1234.667 1.31 19075 20018 2 1234.665901 618.3408 Mitochondrial import inner membrane translocase subunit TIM50 OS=Homo sapiens OX=9606 GN=TIMM50 PE=1 SV=2 9.75 3476.2 - 1.07E+07 - - - -0.8788 - 2.129 0.452 - 435.5 1 2 0 -0.0011 11 0 0 0 1.18E+08 8.99E+07 - - - 4.4233 0.9996 221125_WJC_METTL3_EV_vs_WT_F02.20023.20023.2 0.000372 20-Oct K.IDGLLIDQIQR.D "sp|P82650|RT22_HUMAN,tr|G5E9W7|G5E9W7_HUMAN,tr|A0A7P0MKV3|A0A7P0MKV3_HUMAN,tr|H7C5L9|H7C5L9_HUMAN" 4 1282.7245 1.03 19080 20023 2 1282.724131 642.3695 "28S ribosomal protein S22, mitochondrial OS=Homo sapiens OX=9606 GN=MRPS22 PE=1 SV=1" 4.21 3476.7 - 1.13E+06 - - - -0.2884 - 2.28 0.287 - 410.4 1 2 0 -0.0004 11 0 0 0 1.62E+07 1.57E+07 - - - 3.3903 0.9997 221125_WJC_METTL3_EV_vs_WT_F02.20024.20024.2 1.65E-05 13/26 K.NAPVTFIVDGAVVK[136.11].F sp|Q9H5V9|STEEP_HUMAN 1 1436.8119 0.37 19081 20024 2 1436.808359 719.4132 STING ER exit protein OS=Homo sapiens OX=9606 GN=STEEP1 PE=1 SV=1 5.84 3476.8 - 1.11E+06 - - - -2.4408 - 2.587 0.526 - 440.1 1 2 0 -0.0035 14 0 0 0 1.10E+07 2.96E+07 - - - 5.3102 0.9995 221125_WJC_METTL3_EV_vs_WT_F02.20027.20027.2 1.30E-05 20-Oct K.WENGTFPGWPK.E sp|Q12874|SF3A3_HUMAN 1 1317.6142 999 19084 20027 2 1317.610477 659.8144 Splicing factor 3A subunit 3 OS=Homo sapiens OX=9606 GN=SF3A3 PE=1 SV=1 6 3477.2 - 642278 - - - -2.8423 - 1.969 0.517 - 246.1 1 2 0 -0.0037 11 0 0 0 1.28E+07 0.00E+00 - - - 4.6913 0.9933 221125_WJC_METTL3_EV_vs_WT_F02.20031.20031.2 0.000101 14/26 Q.LDGIHLLDPDVVAR[166.11].F sp|Q86U44|MTA70_HUMAN 1 1541.8441 0.01 19086 20031 2 1541.844687 771.9293 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 4.41 3477.6 - 2.39E+06 - - - 0.3729 - 2.565 0.499 - 574.8 1 1 0 0.0006 14 0 0 0 3.01E+06 3.03E+08 - - - 5.0902 0.9998 221125_WJC_METTL3_EV_vs_WT_F02.20032.20032.2 1.82E-05 20-Nov K.YITGTDILDMK[136.11].L "sp|Q9Y3A6|TMED5_HUMAN,tr|B1AKT3|B1AKT3_HUMAN" 2 1276.6464 0.91 19087 20032 2 1276.645101 639.3305 Transmembrane emp24 domain-containing protein 5 OS=Homo sapiens OX=9606 GN=TMED5 PE=1 SV=1 4.21 3477.8 - 2.23E+06 - - - -1.0488 - 1.942 0.464 - 253.8 1 2 0 -0.0013 11 0 0 0 1.70E+07 1.86E+07 - - - 4.2632 0.9994 221125_WJC_METTL3_EV_vs_WT_F02.20033.20033.2 2.46E-05 15/24 R.AIGFVVGQTDWEK.L "sp|P49750|YLPM1_HUMAN,tr|F8VU51|F8VU51_HUMAN" 2 1448.73 2.82 19088 20033 2 1448.724876 725.3723 YLP motif-containing protein 1 OS=Homo sapiens OX=9606 GN=YLPM1 PE=1 SV=4 4.37 3477.9 - 1.62E+06 - - - -3.5231 - 2.728 0.511 - 814.4 1 2 0 -0.0051 13 0 0 0 3.35E+07 1.19E+07 - - - 5.3893 1 221125_WJC_METTL3_EV_vs_WT_F02.20034.20034.2 9.92E-07 14/28 A.NVILTTGGIDDMC[160.03]LK[136.11].Y "sp|P17987|TCPA_HUMAN,tr|F5GZ03|F5GZ03_HUMAN,tr|F5H282|F5H282_HUMAN,tr|E7EQR6|E7EQR6_HUMAN,tr|E7ERF2|E7ERF2_HUMAN" 5 1656.8306 0.38 19089 20034 2 1656.83052 829.4226 T-complex protein 1 subunit alpha OS=Homo sapiens OX=9606 GN=TCP1 PE=1 SV=1 4.21 3478 - 1.51E+06 - - - -0.0658 - 2.797 0.632 - 504 1 1 0 -0.0001 15 0 0 0 7.34E+06 1.95E+07 - - - 6.2376 1 221125_WJC_METTL3_EV_vs_WT_F02.20037.20037.3 2.65E-06 Dec-52 R.IIPGFMC[160.03]QGGDFTR[166.11].H "sp|Q9Y536|PAL4A_HUMAN,sp|A0A075B759|PAL4E_HUMAN,sp|P0DN26|PAL4F_HUMAN,sp|A0A0B4J2A2|PAL4C_HUMAN,sp|F5H284|PAL4D_HUMAN,sp|A0A075B767|PAL4H_HUMAN,sp|P62937|PPIA_HUMAN,tr|A0A0H2UH34|A0A0H2UH34_HUMAN,tr|C9J5S7|C9J5S7_HUMAN,tr|F8WE65|F8WE65_HUMAN" 10 1607.7464 0.81 19090 20037 3 1607.74656 536.9227 Peptidyl-prolyl cis-trans isomerase A-like 4A OS=Homo sapiens OX=9606 GN=PPIAL4A PE=2 SV=1 5.83 3478.4 - 1.59E+06 - - - 0.1064 - 2.346 0.479 - 138.3 1 2 0 0.0002 14 0 0 0 1.95E+07 2.42E+07 - - - 6.1464 0.9994 221125_WJC_METTL3_EV_vs_WT_F02.20038.20038.2 1.69E-06 15/26 K.NAPVTFIVDGAVVK.F sp|Q9H5V9|STEEP_HUMAN 1 1428.7977 0.37 19091 20038 2 1428.802257 715.4061 STING ER exit protein OS=Homo sapiens OX=9606 GN=STEEP1 PE=1 SV=1 5.84 3478.5 - 1.46E+06 - - - 3.2132 - 2.261 0.538 - 601.5 1 2 0 0.0046 14 0 0 0 1.10E+07 2.96E+07 - - - 5.0605 0.9977 221125_WJC_METTL3_EV_vs_WT_F02.20041.20041.2 1.69E-06 14/24 R.AIGFVVGQTDWEK[136.11].L "sp|P49750|YLPM1_HUMAN,tr|F8VU51|F8VU51_HUMAN" 2 1456.7442 2.69 19094 20041 2 1456.736244 729.3794 YLP motif-containing protein 1 OS=Homo sapiens OX=9606 GN=YLPM1 PE=1 SV=4 4.37 3478.8 - 1.51E+06 - - - -5.4478 - 2.749 0.529 - 698.7 1 2 0 -0.0079 13 0 0 0 3.19E+07 1.19E+07 - - - 5.5411 0.9999 221125_WJC_METTL3_EV_vs_WT_F02.20043.20043.2 0.000568 14/20 K.IDGLLIDQIQR[166.11].D "sp|P82650|RT22_HUMAN,tr|G5E9W7|G5E9W7_HUMAN,tr|A0A7P0MKV3|A0A7P0MKV3_HUMAN,tr|H7C5L9|H7C5L9_HUMAN" 4 1292.7328 1.07 19096 20043 2 1292.734075 647.3737 "28S ribosomal protein S22, mitochondrial OS=Homo sapiens OX=9606 GN=MRPS22 PE=1 SV=1" 4.21 3479.1 - 1.07E+06 - - - 1.0087 - 2.605 0.464 - 804.3 1 2 0 0.0013 11 0 0 0 1.62E+07 1.51E+07 - - - 5.0578 1 221125_WJC_METTL3_EV_vs_WT_F02.20049.20049.2 1.94E-06 14/24 K.TVDNFVALATGEK.G "sp|P23284|PPIB_HUMAN,tr|A0A7P0Z497|A0A7P0Z497_HUMAN,tr|A0A7P0T7U3|A0A7P0T7U3_HUMAN" 3 1363.6983 0.52 19100 20049 2 1363.699061 682.8564 Peptidyl-prolyl cis-trans isomerase B OS=Homo sapiens OX=9606 GN=PPIB PE=1 SV=2 4.37 3479.7 - 2.58E+06 - - - 0.5243 - 2.749 0.562 - 449.7 1 2 0 0.0007 13 0 0 0 1.21E+08 2.31E+08 - - - 5.7871 0.9558 221125_WJC_METTL3_EV_vs_WT_F02.20051.20051.2 0.000339 16-Aug R.FFFDVGSNK.Y sp|Q00577|PURA_HUMAN 1 1059.5025 1.68 19102 20051 2 1059.506306 530.7585 Transcriptional activator protein Pur-alpha OS=Homo sapiens OX=9606 GN=PURA PE=1 SV=2 5.84 3479.8 - 1.52E+06 - - - 3.5488 - 1.428 0.13 - 144.7 2 2 0 0.0038 9 0 0 0 7.03E+07 4.18E+07 - - - 0.8963 0.9998 221125_WJC_METTL3_EV_vs_WT_F02.20052.20052.2 0.000182 20-Nov R.TEMENEFVLIK.K "sp|P05787|K2C8_HUMAN,tr|F8VUG2|F8VUG2_HUMAN,tr|F8VP67|F8VP67_HUMAN,tr|Q8IWY7|Q8IWY7_HUMAN,tr|F8W1U3|F8W1U3_HUMAN" 5 1351.6694 1.03 19103 20052 2 1351.669009 676.842 "Keratin, type II cytoskeletal 8 OS=Homo sapiens OX=9606 GN=KRT8 PE=1 SV=7" 4.25 3479.9 - 2.54E+06 - - - -0.2552 - 2.092 0.426 - 464.2 1 2 0 -0.0003 11 0 0 0 2.15E+08 2.08E+08 - - - 4.1841 0.9974 221125_WJC_METTL3_EV_vs_WT_F02.20053.20053.3 0.0592 Dec-40 K.EFSHIAFLTIK.G "sp|P10619|PPGB_HUMAN,tr|X6R8A1|X6R8A1_HUMAN,tr|A0A7I2V4K5|A0A7I2V4K5_HUMAN,tr|X6R5C5|X6R5C5_HUMAN" 4 1304.7129 4.89 19104 20053 3 1304.713289 435.9116 Lysosomal protective protein OS=Homo sapiens OX=9606 GN=CTSA PE=1 SV=2 6.85 3480 - 1.42E+06 - - - 0.3188 - 1.503 0.266 - 130.1 1 2 0 0.0004 11 0 0 0 1.14E+07 2.32E+06 - - - 2.6631 0.9932 221125_WJC_METTL3_EV_vs_WT_F02.20056.20056.2 0.177 12-Jul K.DIIHFFR[166.11].H "sp|P49959|MRE11_HUMAN,tr|F8W7U8|F8W7U8_HUMAN" 2 956.5108 0.1 19107 20056 2 956.509915 479.2627 Double-strand break repair protein MRE11 OS=Homo sapiens OX=9606 GN=MRE11 PE=1 SV=3 6.74 3480.4 - 956554 - - - -0.8803 - 1.189 0.188 - 173.9 1 2 0 -0.0008 7 0 0 0 9.50E+05 9.41E+06 - - - 0.9778 1 221125_WJC_METTL3_EV_vs_WT_F02.20057.20057.2 5.73E-08 18/30 K.GAVGATIGGVAWIGGK[136.11].S sp|Q8WUH6|TM263_HUMAN 1 1420.7918 0.56 19108 20057 2 1420.789205 711.4032 Transmembrane protein 263 OS=Homo sapiens OX=9606 GN=TMEM263 PE=1 SV=1 8.75 3480.5 - 952777 - - - -1.8257 - 3.588 0.552 - 1133.3 1 2 0 -0.0026 16 0 0 0 2.66E+07 4.74E+07 - - - 6.2583 1 221125_WJC_METTL3_EV_vs_WT_F02.20061.20061.2 1.49E-08 17/28 R.FGGGNPELLTQMVSK[136.11].G "sp|P40939|ECHA_HUMAN,tr|H0YFD6|H0YFD6_HUMAN,tr|A0A2R8Y4F5|A0A2R8Y4F5_HUMAN" 3 1584.8061 0.87 19111 20061 2 1584.803403 793.4103 "Trifunctional enzyme subunit alpha, mitochondrial OS=Homo sapiens OX=9606 GN=HADHA PE=1 SV=2" 6 3481 - 2.31E+06 - - - -1.7195 - 3.42 0.645 - 958.1 1 2 0 -0.0027 15 0 0 0 5.13E+07 5.87E+07 - - - 6.8272 0.9997 221125_WJC_METTL3_EV_vs_WT_F02.20062.20062.2 9.07E-06 26-Oct R.IIPGFMC[160.03]QGGDFTR[166.11].H "sp|Q9Y536|PAL4A_HUMAN,sp|A0A075B759|PAL4E_HUMAN,sp|P0DN26|PAL4F_HUMAN,sp|A0A0B4J2A2|PAL4C_HUMAN,sp|F5H284|PAL4D_HUMAN,sp|A0A075B767|PAL4H_HUMAN,sp|P62937|PPIA_HUMAN,tr|A0A0H2UH34|A0A0H2UH34_HUMAN,tr|C9J5S7|C9J5S7_HUMAN,tr|F8WE65|F8WE65_HUMAN" 10 1607.7464 1.05 19112 20062 2 1607.749382 804.8805 Peptidyl-prolyl cis-trans isomerase A-like 4A OS=Homo sapiens OX=9606 GN=PPIAL4A PE=2 SV=1 5.83 3481.1 - 1.19E+07 - - - 1.8616 - 1.909 0.521 - 281.5 1 2 0 0.003 14 0 0 0 1.84E+08 1.75E+08 - - - 4.5107 0.9969 221125_WJC_METTL3_EV_vs_WT_F02.20065.20065.2 0.233 12-May R.EWDFDLK[136.11].K "sp|Q96EY4|TMA16_HUMAN,tr|H0Y9X1|H0Y9X1_HUMAN" 2 959.448 0.85 19115 20065 2 959.447025 480.7313 Translation machinery-associated protein 16 OS=Homo sapiens OX=9606 GN=TMA16 PE=1 SV=2 4.03 3481.3 - 1.78E+06 - - - -1.0141 - 1.257 0.249 - 166.8 1 2 0 -0.001 7 0 0 0 2.16E+07 2.55E+07 - - - 1.6045 0.9823 221125_WJC_METTL3_EV_vs_WT_F02.20066.20066.2 9.74E-05 20-Nov K.AVLWQDSFSPH.L "sp|Q14671|PUM1_HUMAN,tr|Q5T1Z8|Q5T1Z8_HUMAN,tr|E9PM68|E9PM68_HUMAN,tr|E9PMX1|E9PMX1_HUMAN,tr|H0YEH2|H0YEH2_HUMAN,tr|Q5T1Z4|Q5T1Z4_HUMAN,tr|E9PL65|E9PL65_HUMAN,tr|E9PR38|E9PR38_HUMAN" 8 1285.6091 - 19116 20066 2 1285.606961 643.8118 Pumilio homolog 1 OS=Homo sapiens OX=9606 GN=PUM1 PE=1 SV=3 5.08 3481.4 - 1.57E+06 - - - -1.6926 - 2.29 0.409 - 327.1 1 1 0 -0.0022 11 0 0 0 - - - - - 4.3026 0.9897 221125_WJC_METTL3_EV_vs_WT_F02.20067.20067.2 0.000695 15/22 D.GIHLLDPDVVAR[166.11].F sp|Q86U44|MTA70_HUMAN 1 1313.7331 0.11 19117 20067 2 1313.734782 657.8738 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 5.21 3481.5 - 1.21E+06 - - - 1.2765 - 2.564 0.466 - 739.4 1 1 0 0.0017 12 0 0 0 2.58E+06 2.46E+07 - - - 4.9598 0.9998 221125_WJC_METTL3_EV_vs_WT_F02.20068.20068.2 0.000205 20-Nov R.LNTSELLGEIK.G sp|P35712|SOX6_HUMAN 1 1215.6711 2.3 19118 20068 2 1215.669756 608.8428 Transcription factor SOX-6 OS=Homo sapiens OX=9606 GN=SOX6 PE=1 SV=3 4.53 3481.7 - 1.05E+06 - - - -1.0792 - 2.314 0.432 - 312.1 1 2 0 -0.0013 11 0 0 0 8.27E+06 3.59E+06 - - - 4.501 1 221125_WJC_METTL3_EV_vs_WT_F02.20069.20069.3 0.0027 20/48 K.NILFVITK[136.11]PDVYK[136.11].S "sp|E9PAV3|NACAM_HUMAN,sp|Q9BZK3|NACP4_HUMAN,sp|Q13765|NACA_HUMAN,tr|A0A7I2V473|A0A7I2V473_HUMAN,tr|F8VZJ2|F8VZJ2_HUMAN,tr|F8VNW4|F8VNW4_HUMAN,tr|A0A7I2V2K5|A0A7I2V2K5_HUMAN,tr|F8W0W4|F8W0W4_HUMAN,tr|H0YHX9|H0YHX9_HUMAN,tr|F8VZ58|F8VZ58_HUMAN" 10 1564.92 0.3 19119 20069 3 1564.920121 522.6473 "Nascent polypeptide-associated complex subunit alpha, muscle-specific form OS=Homo sapiens OX=9606 GN=NACA PE=1 SV=1" 8.5 3481.8 - 959515 - - - 0.099 - 3.021 0.416 - 498 1 2 0 0.0002 13 0 0 0 7.83E+07 2.64E+08 - - - 6.1755 0.9978 221125_WJC_METTL3_EV_vs_WT_F02.20075.20075.2 0.0152 14-Aug R.DVDFELIK[136.11].V "sp|P48643|TCPE_HUMAN,tr|E9PCA1|E9PCA1_HUMAN,tr|B7ZAR1|B7ZAR1_HUMAN,tr|E7ENZ3|E7ENZ3_HUMAN" 4 985.5212 0.67 19123 20075 2 985.520787 493.7679 T-complex protein 1 subunit epsilon OS=Homo sapiens OX=9606 GN=CCT5 PE=1 SV=1 4.03 3482.6 - 1.83E+07 - - - -0.3815 - 1.344 0.242 - 163.5 1 2 0 -0.0004 8 0 0 0 4.81E+08 7.21E+08 - - - 1.72 0.9999 221125_WJC_METTL3_EV_vs_WT_F02.20076.20076.2 3.75E-07 26-Sep R.IIPGFMC[160.03]QGGDFTR.H "sp|Q9Y536|PAL4A_HUMAN,sp|A0A075B759|PAL4E_HUMAN,sp|P0DN26|PAL4F_HUMAN,sp|A0A0B4J2A2|PAL4C_HUMAN,sp|F5H284|PAL4D_HUMAN,sp|A0A075B767|PAL4H_HUMAN,sp|P62937|PPIA_HUMAN,tr|A0A0H2UH34|A0A0H2UH34_HUMAN,tr|C9J5S7|C9J5S7_HUMAN,tr|F8WE65|F8WE65_HUMAN" 10 1597.7381 1.05 19124 20076 2 1597.739707 799.8763 Peptidyl-prolyl cis-trans isomerase A-like 4A OS=Homo sapiens OX=9606 GN=PPIAL4A PE=2 SV=1 5.83 3482.6 - 9.00E+06 - - - 0.9939 - 1.936 0.591 - 233.7 1 2 0 0.0016 14 0 0 0 1.84E+08 1.75E+08 - - - 5.0634 0.9998 221125_WJC_METTL3_EV_vs_WT_F02.20077.20077.2 1.87E-05 18-Oct K.SDGIYIINLK.R "sp|P08865|RSSA_HUMAN,tr|C9J9K3|C9J9K3_HUMAN,tr|A0A0C4DG17|A0A0C4DG17_HUMAN,tr|F8WD59|F8WD59_HUMAN" 4 1134.6285 0.79 19125 20077 2 1134.627609 568.3215 40S ribosomal protein SA OS=Homo sapiens OX=9606 GN=RPSA PE=1 SV=4 5.55 3482.6 - 7.40E+06 - - - -0.7632 - 1.983 0.486 - 431.5 1 2 0 -0.0009 10 0 0 0 9.37E+07 1.19E+08 - - - 4.5413 0.9896 221125_WJC_METTL3_EV_vs_WT_F02.20078.20078.2 0.000162 24-Sep K.GPAVGIDLGTTYS.C "sp|P11142|HSP7C_HUMAN,tr|E9PQQ4|E9PQQ4_HUMAN,tr|E9PNE6|E9PNE6_HUMAN,tr|E9PKE3|E9PKE3_HUMAN,tr|E9PLF4|E9PLF4_HUMAN,tr|E9PI65|E9PI65_HUMAN,tr|E9PK54|E9PK54_HUMAN,tr|E9PN25|E9PN25_HUMAN,tr|E9PPY6|E9PPY6_HUMAN,tr|E9PQK7|E9PQK7_HUMAN" 10 1249.619 - 19126 20078 2 1249.61821 625.8168 Heat shock cognate 71 kDa protein OS=Homo sapiens OX=9606 GN=HSPA8 PE=1 SV=1 3.8 3482.7 - 4.25E+06 - - - -0.6586 - 1.608 0.555 - 128.7 1 1 0 -0.0008 13 0 0 0 - - - - - 4.3591 0.9864 221125_WJC_METTL3_EV_vs_WT_F02.20081.20081.2 0.000958 20-Sep R.DATWSPLNHSL.L "sp|Q9BQA1|MEP50_HUMAN,tr|H0Y711|H0Y711_HUMAN" 2 1239.5884 - 19129 20081 2 1239.587844 620.8015 Methylosome protein 50 OS=Homo sapiens OX=9606 GN=WDR77 PE=1 SV=1 5.08 3482.9 - 2.77E+06 - - - -0.4493 - 1.701 0.467 - 276.9 1 1 0 -0.0006 11 0 0 0 - - - - - 3.9272 0.9995 221125_WJC_METTL3_EV_vs_WT_F02.20082.20082.2 0.000242 16-Aug R.FFFDVGSNK[136.11].Y sp|Q00577|PURA_HUMAN 1 1067.5167 1.68 19130 20082 2 1067.516589 534.7656 Transcriptional activator protein Pur-alpha OS=Homo sapiens OX=9606 GN=PURA PE=1 SV=2 5.84 3482.9 - 2.61E+06 - - - -0.1471 - 1.47 0.392 - 120.9 1 2 0 -0.0002 9 0 0 0 7.03E+07 4.18E+07 - - - 3.0508 0.9997 221125_WJC_METTL3_EV_vs_WT_F02.20083.20083.2 0.00372 20-Oct R.SELPDYYLTIK.K "sp|Q86U86|PB1_HUMAN,tr|H0Y5B5|H0Y5B5_HUMAN,tr|E7EVG2|E7EVG2_HUMAN" 3 1340.6864 1.49 19131 20083 2 1340.686469 671.3505 Protein polybromo-1 OS=Homo sapiens OX=9606 GN=PBRM1 PE=1 SV=1 4.37 3483 - 1.86E+06 - - - 0.0634 - 1.957 0.366 - 299.3 1 2 0 0.0001 11 0 0 0 6.93E+07 4.67E+07 - - - 3.5606 1 221125_WJC_METTL3_EV_vs_WT_F02.20085.20085.3 4.56E-07 14/48 K.TVDNFVALATGEK[136.11].G "sp|P23284|PPIB_HUMAN,tr|A0A7P0Z497|A0A7P0Z497_HUMAN,tr|A0A7P0T7U3|A0A7P0T7U3_HUMAN" 3 1371.7125 0.76 19133 20085 3 1371.712623 458.2448 Peptidyl-prolyl cis-trans isomerase B OS=Homo sapiens OX=9606 GN=PPIB PE=1 SV=2 4.37 3483.2 - 1.54E+06 - - - 0.0561 - 2.397 0.518 - 358.7 1 2 0 0.0001 13 0 0 0 1.13E+07 1.49E+07 - - - 6.6854 1 221125_WJC_METTL3_EV_vs_WT_F02.20086.20086.2 7.61E-06 14/24 K.IC[160.03]LEDNVLMSGVK.N "sp|Q92520|FAM3C_HUMAN,tr|C9JMN4|C9JMN4_HUMAN,tr|C9JP35|C9JP35_HUMAN" 3 1476.7316 1.25 19134 20086 2 1476.728643 739.3731 Protein FAM3C OS=Homo sapiens OX=9606 GN=FAM3C PE=1 SV=1 4.37 3483.4 - 1.38E+06 - - - -2.0275 - 2.721 0.56 - 614 1 2 0 -0.003 13 0 0 0 6.45E+07 5.15E+07 - - - 5.7453 0.9999 221125_WJC_METTL3_EV_vs_WT_F02.20087.20087.2 0.000237 16-Nov K.C[160.03]FSVLGFC[160.03]K.S sp|P13010|XRCC5_HUMAN 1 1116.5096 0.82 19135 20087 2 1116.509034 559.2621 X-ray repair cross-complementing protein 5 OS=Homo sapiens OX=9606 GN=XRCC5 PE=1 SV=3 8.06 3483.4 - 1.19E+06 - - - -0.5275 - 2.179 0.51 - 442.9 1 2 0 -0.0006 9 0 0 0 1.92E+07 2.34E+07 - - - 5.061 0.9712 221125_WJC_METTL3_EV_vs_WT_F02.20088.20088.2 0.000155 Nov-32 K.QPVPVGGAISTAQAQAF.L "sp|P14859|PO2F1_HUMAN,tr|A0A0A0MT46|A0A0A0MT46_HUMAN" 2 1640.8522 - 19136 20088 2 1640.85559 821.4334 "POU domain, class 2, transcription factor 1 OS=Homo sapiens OX=9606 GN=POU2F1 PE=1 SV=2" 5.52 3483.6 - 858779 - - - 2.0532 - 2.135 0.425 - 246.3 1 1 0 0.0034 17 0 0 0 - - - - - 4.0437 0.9997 221125_WJC_METTL3_EV_vs_WT_F02.20090.20090.3 6.60E-05 15/48 K.TVDNFVALATGEK.G "sp|P23284|PPIB_HUMAN,tr|A0A7P0Z497|A0A7P0Z497_HUMAN,tr|A0A7P0T7U3|A0A7P0T7U3_HUMAN" 3 1363.6983 0.76 19138 20090 3 1363.697343 455.5734 Peptidyl-prolyl cis-trans isomerase B OS=Homo sapiens OX=9606 GN=PPIB PE=1 SV=2 4.37 3483.8 - 797700 - - - -0.7355 - 1.785 0.375 - 221.9 1 2 0 -0.001 13 0 0 0 1.13E+07 1.49E+07 - - - 4.2916 0.8771 221125_WJC_METTL3_EV_vs_WT_F02.20092.20092.2 0.0107 16-Jun K.NGQDLGVAF.K "sp|Q00839|HNRPU_HUMAN,tr|A0A1W2PQL0|A0A1W2PQL0_HUMAN,tr|A0A1W2PPL4|A0A1W2PPL4_HUMAN,tr|A0A1W2PQ74|A0A1W2PQ74_HUMAN,tr|Q5RI18|Q5RI18_HUMAN,tr|A0A1W2PP35|A0A1W2PP35_HUMAN,tr|A0A1W2PPS1|A0A1W2PPS1_HUMAN,tr|A0A1W2PRZ7|A0A1W2PRZ7_HUMAN,tr|A0A1W2PPH7|A0A1W2PPH7_HUMAN,tr|A0A1W2PP34|A0A1W2PP34_HUMAN,tr|A0A1X7SBS1|A0A1X7SBS1_HUMAN" 11 919.4399 - 19140 20092 2 919.439611 460.7272 Heterogeneous nuclear ribonucleoprotein U OS=Homo sapiens OX=9606 GN=HNRNPU PE=1 SV=6 3.8 3484.1 - 543697 - - - -0.3644 - 1.018 0.35 - 86.8 1 1 0 -0.0003 9 0 0 0 - - - - - 1.6776 1 221125_WJC_METTL3_EV_vs_WT_F02.20096.20096.2 2.80E-09 16/30 K.GAVGATIGGVAWIGGK.S sp|Q8WUH6|TM263_HUMAN 1 1412.7776 0.55 19142 20096 2 1412.78264 707.3961 Transmembrane protein 263 OS=Homo sapiens OX=9606 GN=TMEM263 PE=1 SV=1 8.75 3484.5 - 3.46E+06 - - - 3.5681 - 3.139 0.531 - 798.3 1 2 0 0.005 16 0 0 0 2.63E+07 4.74E+07 - - - 5.7737 1 221125_WJC_METTL3_EV_vs_WT_F02.20098.20098.2 0.000783 18/30 K.IFVGGLSVNTTVEDVK.Q "sp|O43347|MSI1H_HUMAN,tr|H0YHB7|H0YHB7_HUMAN" 2 1676.8985 1.38 19144 20098 2 1676.897563 839.4565 RNA-binding protein Musashi homolog 1 OS=Homo sapiens OX=9606 GN=MSI1 PE=1 SV=1 4.37 3484.8 - 2.18E+06 - - - -0.56 - 3.586 0.545 - 883.6 1 2 0 -0.0009 16 0 0 0 4.52E+08 3.27E+08 - - - 6.2057 0.9993 221125_WJC_METTL3_EV_vs_WT_F02.20101.20101.2 0.00173 14-Aug R.EENLFSWK.G sp|P38432|COIL_HUMAN 1 1051.4975 0.28 19147 20101 2 1051.496122 526.756 Coilin OS=Homo sapiens OX=9606 GN=COIL PE=1 SV=1 4.53 3485.1 - 1.84E+06 - - - -1.2734 - 1.458 0.378 - 297.2 1 2 0 -0.0013 8 0 0 0 1.82E+07 6.45E+07 - - - 2.9697 1 221125_WJC_METTL3_EV_vs_WT_F02.20102.20102.2 5.87E-08 14/26 R.IESIQLMMDSETGR[166.11].S "sp|Q14498|RBM39_HUMAN,tr|A0A0U1RQW2|A0A0U1RQW2_HUMAN,tr|A0A0U1RQH7|A0A0U1RQH7_HUMAN,tr|G3XAC6|G3XAC6_HUMAN" 4 1618.757 10.77 19148 20102 2 1618.754127 810.3858 RNA-binding protein 39 OS=Homo sapiens OX=9606 GN=RBM39 PE=1 SV=2 4.14 3485.3 - 1.68E+06 - - - -1.7828 - 3.055 0.607 - 760.8 1 2 0 -0.0029 14 0 0 0 1.17E+08 1.09E+07 - - - 6.3259 0.9993 221125_WJC_METTL3_EV_vs_WT_F02.20103.20103.2 0.00687 30-Dec R.MIASQVVDINLAAEPK.V "sp|P0DMR1|HNRC4_HUMAN,sp|O60812|HNRC1_HUMAN,sp|B7ZW38|HNRC3_HUMAN,tr|A0A0G2JPF8|A0A0G2JPF8_HUMAN" 4 1697.9022 1.62 19149 20103 2 1697.903608 849.9584 Heterogeneous nuclear ribonucleoprotein C-like 4 OS=Homo sapiens OX=9606 GN=HNRNPCL4 PE=3 SV=1 4.37 3485.4 - 1.50E+06 - - - 0.8251 - 1.927 0.312 - 222 1 2 0 0.0014 16 0 0 0 2.86E+08 1.76E+08 - - - 2.9577 0.9995 221125_WJC_METTL3_EV_vs_WT_F02.20104.20104.2 0.00181 30-Oct R.MIASQVVDINLAAEPK[136.11].V "sp|P0DMR1|HNRC4_HUMAN,sp|O60812|HNRC1_HUMAN,sp|B7ZW38|HNRC3_HUMAN,tr|A0A0G2JPF8|A0A0G2JPF8_HUMAN" 4 1705.9164 1.62 19150 20104 2 1705.916829 853.9655 Heterogeneous nuclear ribonucleoprotein C-like 4 OS=Homo sapiens OX=9606 GN=HNRNPCL4 PE=3 SV=1 4.37 3485.5 - 1.10E+06 - - - 0.2474 - 1.781 0.354 - 152.8 1 2 0 0.0004 16 0 0 0 2.85E+08 1.76E+08 - - - 3.0745 1 221125_WJC_METTL3_EV_vs_WT_F02.20105.20105.2 9.57E-10 14/30 Q.GFNQGLDC[160.03]DVIVAEVR[166.11].S sp|Q86U44|MTA70_HUMAN 1 1800.8704 0.001 19151 20105 2 1800.867248 901.4425 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 4.03 3485.6 - 1.01E+06 - - - -1.7525 - 3.048 0.658 - 743.1 1 1 0 -0.0032 16 0 0 0 0.00E+00 5.92E+07 - - - 6.64 1 221125_WJC_METTL3_EV_vs_WT_F02.20106.20106.2 1.36E-08 16/30 K.GLVYETSVLDPDEGIR.F "sp|O75390|CISY_HUMAN,tr|F8VX07|F8VX07_HUMAN,tr|F8VZK9|F8VZK9_HUMAN,tr|F8VRP1|F8VRP1_HUMAN,tr|B4DJV2|B4DJV2_HUMAN,tr|F8VPA1|F8VPA1_HUMAN,tr|A0A0C4DGI3|A0A0C4DGI3_HUMAN,tr|F8W4S1|F8W4S1_HUMAN,tr|H0YH82|H0YH82_HUMAN,tr|F8W1S4|F8W1S4_HUMAN,tr|F8VTT8|F8VTT8_HUMAN,tr|F8VPF9|F8VPF9_HUMAN,tr|F8W642|F8W642_HUMAN,tr|F8VX68|F8VX68_HUMAN" 14 1761.8785 1.2 19152 20106 2 1761.873071 881.9465 "Citrate synthase, mitochondrial OS=Homo sapiens OX=9606 GN=CS PE=1 SV=2" 3.92 3485.8 - 862819 - - - -3.0785 - 3.12 0.618 - 605.4 1 2 0 -0.0054 16 0 0 0 1.97E+07 1.64E+07 - - - 6.4013 0.9966 221125_WJC_METTL3_EV_vs_WT_F02.20107.20107.2 0.000179 16-Aug R.VC[160.03]MDFNIIR.K "sp|P41252|SYIC_HUMAN,tr|A0A804HL54|A0A804HL54_HUMAN,tr|A0A804HKU1|A0A804HKU1_HUMAN,tr|A0A804HK69|A0A804HK69_HUMAN,tr|A0A804HIV9|A0A804HIV9_HUMAN,tr|A0A804HJN6|A0A804HJN6_HUMAN,tr|A0A804HHW9|A0A804HHW9_HUMAN,tr|A0A0A0MSX9|A0A0A0MSX9_HUMAN,tr|J3KR24|J3KR24_HUMAN,tr|A0A804HIG2|A0A804HIG2_HUMAN,tr|A0A804HJ36|A0A804HJ36_HUMAN" 11 1166.5576 0.57 19153 20107 2 1166.552138 584.2861 "Isoleucine--tRNA ligase, cytoplasmic OS=Homo sapiens OX=9606 GN=IARS1 PE=1 SV=2" 5.8 3485.9 - 783798 - - - -4.7122 - 1.872 0.423 - 268.7 1 2 0 -0.0055 9 0 0 0 6.22E+06 1.09E+07 - - - 3.9775 0.9096 221125_WJC_METTL3_EV_vs_WT_F02.20108.20108.2 0.125 30-Sep K.VQGGALEDSQLVAGVA.F sp|Q99832|TCPH_HUMAN 1 1512.7784 - 19154 20108 2 1512.777767 757.3965 T-complex protein 1 subunit eta OS=Homo sapiens OX=9606 GN=CCT7 PE=1 SV=2 3.67 3486 - 702603 - - - -0.4098 - 1.685 0.221 - 166.3 1 1 0 -0.0006 16 0 0 0 - - - - - 1.9559 0.9974 221125_WJC_METTL3_EV_vs_WT_F02.20109.20109.2 3.83E-09 14/24 K.VAGYAALLEQYQK.A "sp|P54920|SNAA_HUMAN,tr|M0R2M1|M0R2M1_HUMAN,tr|M0R027|M0R027_HUMAN,tr|M0R058|M0R058_HUMAN,tr|M0R0Y2|M0R0Y2_HUMAN" 5 1452.7613 1.36 19155 20109 2 1452.769495 727.3879 Alpha-soluble NSF attachment protein OS=Homo sapiens OX=9606 GN=NAPA PE=1 SV=3 5.97 3486.2 - 673051 - - - 5.6547 - 2.672 0.556 - 711.3 1 2 0 0.0082 13 0 0 0 2.09E+07 1.53E+07 - - - 5.6675 0.9998 221125_WJC_METTL3_EV_vs_WT_F02.20110.20110.3 0.0266 Oct-40 K.LILPHVDIQLK[136.11].Y sp|P48735|IDHP_HUMAN 1 1295.8057 1.82 19156 20110 3 1295.804892 432.9425 "Isocitrate dehydrogenase [NADP], mitochondrial OS=Homo sapiens OX=9606 GN=IDH2 PE=1 SV=2" 6.74 3486.3 - 647876 - - - -0.5911 - 1.889 0.391 - 126.7 1 2 0 -0.0008 11 0 0 0 8.80E+06 4.82E+06 - - - 4.706 1 221125_WJC_METTL3_EV_vs_WT_F02.20113.20113.2 0.000161 13/24 K.IC[160.03]LEDNVLMSGVK[136.11].N "sp|Q92520|FAM3C_HUMAN,tr|C9JMN4|C9JMN4_HUMAN,tr|C9JP35|C9JP35_HUMAN" 3 1484.7458 1.25 19157 20113 2 1484.742478 743.3802 Protein FAM3C OS=Homo sapiens OX=9606 GN=FAM3C PE=1 SV=1 4.37 3486.7 - 5.12E+06 - - - -2.2623 - 2.771 0.563 - 608.3 1 2 0 -0.0034 13 0 0 0 6.45E+07 5.15E+07 - - - 5.8141 1 221125_WJC_METTL3_EV_vs_WT_F02.20117.20117.3 0.000313 13/48 R.SLFSSIGEVESAK.L "sp|Q15717|ELAV1_HUMAN,tr|M0QZR9|M0QZR9_HUMAN" 2 1352.6824 1.23 19161 20117 3 1352.681685 451.9014 ELAV-like protein 1 OS=Homo sapiens OX=9606 GN=ELAVL1 PE=1 SV=2 4.53 3486.9 - 2.97E+06 - - - -0.4997 - 2.423 0.476 - 216.7 1 2 0 -0.0007 13 0 0 0 5.59E+07 4.56E+07 - - - 6.2463 0.9999 221125_WJC_METTL3_EV_vs_WT_F02.20119.20119.2 0.0699 18-Dec K.NPGLWLESVR.L sp|O94906|PRP6_HUMAN 1 1169.6193 3.6 19163 20119 2 1169.617982 585.8169 Pre-mRNA-processing factor 6 OS=Homo sapiens OX=9606 GN=PRPF6 PE=1 SV=1 6 3487.1 - 2.23E+06 - - - -1.1328 - 2.41 0.468 - 800.2 1 2 0 -0.0013 10 0 0 0 3.03E+07 8.42E+06 - - - 4.9525 0.9992 221125_WJC_METTL3_EV_vs_WT_F02.20120.20120.3 0.0143 Oct-48 R.SLFSSIGEVESAK[136.11].L "sp|Q15717|ELAV1_HUMAN,tr|M0QZR9|M0QZR9_HUMAN" 2 1360.6966 1.22 19164 20120 3 1360.695542 454.5728 ELAV-like protein 1 OS=Homo sapiens OX=9606 GN=ELAVL1 PE=1 SV=2 4.53 3487.2 - 1.93E+06 - - - -0.7489 - 1.766 0.308 - 85.9 1 2 0 -0.001 13 0 0 0 5.59E+07 4.60E+07 - - - 3.5156 1 221125_WJC_METTL3_EV_vs_WT_F02.20121.20121.2 4.07E-11 16/30 K.GLVYETSVLDPDEGIR[166.11].F "sp|O75390|CISY_HUMAN,tr|F8VX07|F8VX07_HUMAN,tr|F8VZK9|F8VZK9_HUMAN,tr|F8VRP1|F8VRP1_HUMAN,tr|B4DJV2|B4DJV2_HUMAN,tr|F8VPA1|F8VPA1_HUMAN,tr|A0A0C4DGI3|A0A0C4DGI3_HUMAN,tr|F8W4S1|F8W4S1_HUMAN,tr|H0YH82|H0YH82_HUMAN,tr|F8W1S4|F8W1S4_HUMAN,tr|F8VTT8|F8VTT8_HUMAN,tr|F8VPF9|F8VPF9_HUMAN,tr|F8W642|F8W642_HUMAN,tr|F8VX68|F8VX68_HUMAN" 14 1771.8868 1.2 19165 20121 2 1771.884774 886.9507 "Citrate synthase, mitochondrial OS=Homo sapiens OX=9606 GN=CS PE=1 SV=2" 3.92 3487.3 - 1.34E+06 - - - -1.1237 - 3.151 0.655 - 606 1 2 0 -0.002 16 0 0 0 1.97E+07 1.64E+07 - - - 6.6999 1 221125_WJC_METTL3_EV_vs_WT_F02.20122.20122.2 1.14E-07 14/24 K.SLVDLTAVDVPTR[166.11].Q "sp|O75489|NDUS3_HUMAN,tr|E9PS48|E9PS48_HUMAN" 2 1394.7645 1.02 19166 20122 2 1394.766355 698.3895 "NADH dehydrogenase [ubiquinone] iron-sulfur protein 3, mitochondrial OS=Homo sapiens OX=9606 GN=NDUFS3 PE=1 SV=1" 4.21 3487.4 - 1.30E+06 - - - 1.3551 - 2.871 0.576 - 823.8 1 2 0 0.0019 13 0 0 0 3.98E+07 3.89E+07 - - - 6.0016 0.9999 221125_WJC_METTL3_EV_vs_WT_F02.20123.20123.3 1.14E-05 Dec-36 R.FWYFVSQLKK.M "sp|Q02543|RL18A_HUMAN,tr|M0R3D6|M0R3D6_HUMAN,tr|M0R117|M0R117_HUMAN,tr|M0R1A7|M0R1A7_HUMAN" 4 1344.723 0.61 19167 20123 3 1344.721096 449.2483 60S ribosomal protein L18a OS=Homo sapiens OX=9606 GN=RPL18A PE=1 SV=2 9.7 3487.6 - 1.13E+06 - - - -1.4486 - 2.112 0.488 - 160 1 2 0 -0.0019 10 0 0 0 1.24E+07 2.02E+07 - - - 6.1636 0.9998 221125_WJC_METTL3_EV_vs_WT_F02.20127.20127.2 0.000273 14/24 K.EIDLLLGQTDDTR[166.11].Y "sp|O75643|U520_HUMAN,tr|A0A494C1A5|A0A494C1A5_HUMAN" 2 1497.755 2.1 19171 20127 2 1497.757778 749.8848 U5 small nuclear ribonucleoprotein 200 kDa helicase OS=Homo sapiens OX=9606 GN=SNRNP200 PE=1 SV=2 3.84 3488.1 - 786660 - - - 1.8401 - 2.996 0.44 - 747.1 1 2 0 0.0028 13 0 0 0 4.46E+07 2.12E+07 - - - 5.1062 0.9998 221125_WJC_METTL3_EV_vs_WT_F02.20130.20130.3 0.000113 13/60 K.GAVGATIGGVAWIGGK.S sp|Q8WUH6|TM263_HUMAN 1 1412.7776 0.81 19173 20130 3 1412.77605 471.9331 Transmembrane protein 263 OS=Homo sapiens OX=9606 GN=TMEM263 PE=1 SV=1 8.75 3488.4 - 503457 - - - -1.0964 - 2.271 0.368 - 190.4 1 2 0 -0.0015 16 0 0 0 8.86E+06 1.10E+07 - - - 4.747 0.9998 221125_WJC_METTL3_EV_vs_WT_F02.20132.20132.3 0.000792 Dec-60 R.MIASQVVDINLAAEPK.V "sp|P0DMR1|HNRC4_HUMAN,sp|O60812|HNRC1_HUMAN,sp|B7ZW38|HNRC3_HUMAN,tr|A0A0G2JPF8|A0A0G2JPF8_HUMAN" 4 1697.9022 1.58 19174 20132 3 1697.902369 566.9747 Heterogeneous nuclear ribonucleoprotein C-like 4 OS=Homo sapiens OX=9606 GN=HNRNPCL4 PE=3 SV=1 4.37 3488.6 - 7.23E+06 - - - 0.0954 - 2.199 0.371 - 181 1 2 0 0.0002 16 0 0 0 1.58E+08 1.00E+08 - - - 4.6981 0.9997 221125_WJC_METTL3_EV_vs_WT_F02.20135.20135.3 0.0053 Oct-60 R.MIASQVVDINLAAEPK[136.11].V "sp|P0DMR1|HNRC4_HUMAN,sp|O60812|HNRC1_HUMAN,sp|B7ZW38|HNRC3_HUMAN,tr|A0A0G2JPF8|A0A0G2JPF8_HUMAN" 4 1705.9164 1.57 19177 20135 3 1705.915735 569.6461 Heterogeneous nuclear ribonucleoprotein C-like 4 OS=Homo sapiens OX=9606 GN=HNRNPCL4 PE=3 SV=1 4.37 3488.8 - 5.69E+06 - - - -0.3939 - 1.974 0.358 - 98.2 1 2 0 -0.0007 16 0 0 0 1.57E+08 1.00E+08 - - - 4.2761 0.9985 221125_WJC_METTL3_EV_vs_WT_F02.20136.20136.2 0.00035 16-Sep K.GIFLGDQWR.D "sp|Q14671|PUM1_HUMAN,tr|Q5T1Z8|Q5T1Z8_HUMAN,tr|H0YEH2|H0YEH2_HUMAN,tr|Q5T1Z4|Q5T1Z4_HUMAN" 4 1090.556 0.33 19178 20136 2 1090.552546 546.2853 Pumilio homolog 1 OS=Homo sapiens OX=9606 GN=PUM1 PE=1 SV=3 5.84 3488.8 - 4.31E+06 - - - -3.1479 - 1.599 0.429 - 274.9 1 2 0 -0.0034 9 0 0 0 3.05E+07 9.12E+07 - - - 3.5665 0.9999 221125_WJC_METTL3_EV_vs_WT_F02.20137.20137.2 4.62E-05 15/28 R.IPSIVSSPLNSPLDR.S sp|P49790|NU153_HUMAN 1 1593.8726 1.7 19179 20137 2 1593.870609 797.9436 Nuclear pore complex protein Nup153 OS=Homo sapiens OX=9606 GN=NUP153 PE=1 SV=2 5.84 3488.9 - 3.41E+06 - - - -1.263 - 2.968 0.508 - 746.3 1 2 0 -0.002 15 0 0 0 6.46E+07 3.80E+07 - - - 5.4671 0.9999 221125_WJC_METTL3_EV_vs_WT_F02.20140.20140.2 1.54E-06 13/22 R.AAMEALVVEVTK[136.11].Q sp|Q08211|DHX9_HUMAN 1 1267.6937 1.01 19182 20140 2 1267.694094 634.8541 ATP-dependent RNA helicase A OS=Homo sapiens OX=9606 GN=DHX9 PE=1 SV=4 4.53 3489 - 2.75E+06 - - - 0.2919 - 2.892 0.523 - 576.2 1 2 0 0.0004 12 0 0 0 6.01E+07 5.94E+07 - - - 5.6979 1 221125_WJC_METTL3_EV_vs_WT_F02.20141.20141.3 1.00E-06 13/60 K.IFVGGLSVNTTVEDVK.Q "sp|O43347|MSI1H_HUMAN,tr|H0YHB7|H0YHB7_HUMAN" 2 1676.8985 1.13 19183 20141 3 1676.900689 559.9734 RNA-binding protein Musashi homolog 1 OS=Homo sapiens OX=9606 GN=MSI1 PE=1 SV=1 4.37 3489.1 - 2.55E+06 - - - 1.3042 - 2.442 0.487 - 213 1 2 0 0.0022 16 0 0 0 3.88E+07 3.42E+07 - - - 6.2598 1 221125_WJC_METTL3_EV_vs_WT_F02.20142.20142.3 0.000168 Dec-60 K.IFVGGLSVNTTVEDVK[136.11].Q "sp|O43347|MSI1H_HUMAN,tr|H0YHB7|H0YHB7_HUMAN" 2 1684.9127 1.49 19184 20142 3 1684.91299 562.6448 RNA-binding protein Musashi homolog 1 OS=Homo sapiens OX=9606 GN=MSI1 PE=1 SV=1 4.37 3489.2 - 2.19E+06 - - - 0.1709 - 2.367 0.477 - 140.8 1 2 0 0.0003 16 0 0 0 3.65E+07 2.44E+07 - - - 6.0688 0.9995 221125_WJC_METTL3_EV_vs_WT_F02.20143.20143.2 0.0309 13/28 R.IPSIVSSPLNSPLDR[166.11].S sp|P49790|NU153_HUMAN 1 1603.8809 1.7 19185 20143 2 1603.877036 802.9477 Nuclear pore complex protein Nup153 OS=Homo sapiens OX=9606 GN=NUP153 PE=1 SV=2 5.84 3489.2 - 2.12E+06 - - - -2.4042 - 2.58 0.399 - 584 1 2 0 -0.0039 15 0 0 0 6.46E+07 3.80E+07 - - - 4.317 0.9999 221125_WJC_METTL3_EV_vs_WT_F02.20144.20144.3 0.000237 13/48 K.VIIEYPTLHVVLK.G sp|Q9NWK9|BCD1_HUMAN 1 1522.9123 1.24 19186 20144 3 1522.914132 508.6447 Box C\D snoRNA protein 1 OS=Homo sapiens OX=9606 GN=ZNHIT6 PE=1 SV=1 6.72 3489.3 - 1.30E+06 - - - 1.2016 - 2.13 0.397 - 144.9 1 2 0 0.0018 13 0 0 0 1.43E+07 1.16E+07 - - - 5.0157 0.9241 221125_WJC_METTL3_EV_vs_WT_F02.20145.20145.2 0.0171 20-Aug R.GALQNIIPAST.G "sp|P04406|G3P_HUMAN,tr|E7EUT5|E7EUT5_HUMAN" 2 1083.5924 - 19187 20145 2 1083.592386 542.8035 Glyceraldehyde-3-phosphate dehydrogenase OS=Homo sapiens OX=9606 GN=GAPDH PE=1 SV=3 5.52 3489.4 - 1.26E+06 - - - -0.0351 - 1.506 0.264 - 124.1 1 1 0 0 11 0 0 0 - - - - - 2.0986 0.9999 221125_WJC_METTL3_EV_vs_WT_F02.20148.20148.3 4.24E-05 Dec-44 R.AAMEALVVEVTK[136.11].Q sp|Q08211|DHX9_HUMAN 1 1267.6937 0.77 19190 20148 3 1267.693655 423.5719 ATP-dependent RNA helicase A OS=Homo sapiens OX=9606 GN=DHX9 PE=1 SV=4 4.53 3489.8 - 588286 - - - -0.0544 - 2.328 0.385 - 312.6 1 2 0 -0.0001 12 0 0 0 8.85E+06 1.14E+07 - - - 5.1746 1 221125_WJC_METTL3_EV_vs_WT_F02.20149.20149.3 2.94E-05 13/44 R.AAMEALVVEVTK.Q sp|Q08211|DHX9_HUMAN 1 1259.6795 0.77 19191 20149 3 1259.679918 420.9005 ATP-dependent RNA helicase A OS=Homo sapiens OX=9606 GN=DHX9 PE=1 SV=4 4.53 3489.9 - 436717 - - - 0.3128 - 2.723 0.494 - 367.9 1 2 0 0.0004 12 0 0 0 8.85E+06 1.14E+07 - - - 6.8242 0.9984 221125_WJC_METTL3_EV_vs_WT_F02.20153.20153.2 0.226 20-Nov K.NLIDAGVDALR[166.11].V "sp|P12268|IMDH2_HUMAN,tr|A0A7I2YQK5|A0A7I2YQK5_HUMAN,tr|H0Y4R1|H0Y4R1_HUMAN,tr|A0A7I2V2T3|A0A7I2V2T3_HUMAN,tr|E7ETK5|E7ETK5_HUMAN" 5 1165.6331 0.63 19193 20153 2 1165.629017 583.8238 Inosine-5'-monophosphate dehydrogenase 2 OS=Homo sapiens OX=9606 GN=IMPDH2 PE=1 SV=2 4.21 3490.3 - 6.77E+06 - - - -3.4659 - 2.152 0.36 - 490.8 1 2 0 -0.004 11 0 0 0 9.42E+07 1.50E+08 - - - 3.772 1 221125_WJC_METTL3_EV_vs_WT_F02.20154.20154.2 8.04E-06 14/26 K.VGEIFSAAGAAFTK.L "sp|Q8IXM2|BAP18_HUMAN,tr|H0YIS7|H0YIS7_HUMAN,tr|F8W038|F8W038_HUMAN" 3 1367.7085 1.25 19194 20154 2 1367.70964 684.8615 Chromatin complexes subunit BAP18 OS=Homo sapiens OX=9606 GN=BAP18 PE=1 SV=1 5.97 3490.4 - 5.54E+06 - - - 0.8218 - 3.046 0.542 - 695.6 1 2 0 0.0011 14 0 0 0 1.25E+08 1.00E+08 - - - 5.839 0.9983 221125_WJC_METTL3_EV_vs_WT_F02.20155.20155.3 4.77E-06 15/52 Q.LDGIHLLDPDVVAR.F sp|Q86U44|MTA70_HUMAN 1 1531.8358 0.02 19195 20155 3 1531.836369 511.6192 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 4.41 3490.4 - 3.40E+06 - - - 0.344 - 3.21 0.519 - 415.1 1 1 0 0.0005 14 0 0 0 7.34E+07 3.93E+09 - - - 7.4256 1 221125_WJC_METTL3_EV_vs_WT_F02.20156.20156.2 2.88E-09 21/38 K.GNPQGFNQGLDC[160.03]DVIVAEVR[166.11].S sp|Q86U44|MTA70_HUMAN 1 2197.0461 0.001 19196 20156 2 2198.044822 1099.5303 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 4.03 3490.6 - 2.16E+06 - - - 454.5585 - 3.397 0.651 - 1082.7 1 2 0 0.9987 20 0 0 0 0.00E+00 3.28E+07 - - - 6.5422 0.9993 221125_WJC_METTL3_EV_vs_WT_F02.20158.20158.2 7.68E-07 13/24 K.YAC[160.03]GLWGLSPASR[166.11].K "tr|H7C561|H7C561_HUMAN,tr|H7C0N4|H7C0N4_HUMAN" 2 1446.6953 1.21 19198 20158 2 1446.690581 724.3549 Splicing factor 1 (Fragment) OS=Homo sapiens OX=9606 GN=SF1 PE=1 SV=8 8.22 3490.7 - 1.21E+06 - - - -3.2896 - 2.314 0.494 - 599.4 1 2 0 -0.0048 13 0 0 0 3.37E+07 2.78E+07 - - - 4.8415 1 221125_WJC_METTL3_EV_vs_WT_F02.20160.20160.2 3.27E-09 16/26 K.VPDNYGDEIAIELR[166.11].S sp|Q92900|RENT1_HUMAN 1 1612.7972 0.99 19200 20160 2 1612.797902 807.4059 Regulator of nonsense transcripts 1 OS=Homo sapiens OX=9606 GN=UPF1 PE=1 SV=2 3.92 3491 - 944227 - - - 0.4216 - 3.166 0.683 - 1057.3 1 2 0 0.0007 14 0 0 0 2.83E+07 2.85E+07 - - - 6.9775 0.9999 221125_WJC_METTL3_EV_vs_WT_F02.20161.20161.2 5.42E-07 20-Dec K.NLDFGIDMDSR.L "sp|Q8NE71|ABCF1_HUMAN,tr|Q5STZ8|Q5STZ8_HUMAN,tr|H0YGW7|H0YGW7_HUMAN" 3 1281.566 0.11 19201 20161 2 1281.565646 641.7903 ATP-binding cassette sub-family F member 1 OS=Homo sapiens OX=9606 GN=ABCF1 PE=1 SV=2 3.93 3491.1 - 908053 - - - -0.238 - 2.162 0.618 - 537.1 1 2 0 -0.0003 11 0 0 0 7.57E+06 7.11E+07 - - - 5.6913 0.9996 221125_WJC_METTL3_EV_vs_WT_F02.20162.20162.3 4.89E-05 13/56 K.ILAQVVGDVDTSLPR.T sp|Q15029|U5S1_HUMAN 1 1581.8726 4.56 19202 20162 3 1581.878372 528.2982 116 kDa U5 small nuclear ribonucleoprotein component OS=Homo sapiens OX=9606 GN=EFTUD2 PE=1 SV=1 4.21 3491.3 - 864087 - - - 3.6349 - 2.497 0.427 - 178.3 1 2 0 0.0058 15 0 0 0 1.54E+08 3.37E+07 - - - 5.6868 0.9999 221125_WJC_METTL3_EV_vs_WT_F02.20163.20163.3 0.00288 14/52 K.VGEIFSAAGAAFTK.L "sp|Q8IXM2|BAP18_HUMAN,tr|H0YIS7|H0YIS7_HUMAN,tr|F8W038|F8W038_HUMAN" 3 1367.7085 1.53 19203 20163 3 1367.708591 456.9101 Chromatin complexes subunit BAP18 OS=Homo sapiens OX=9606 GN=BAP18 PE=1 SV=1 5.97 3491.4 - 829505 - - - 0.0548 - 2.952 0.399 - 234 1 2 0 0.0001 14 0 0 0 1.48E+07 9.69E+06 - - - 5.8652 1 221125_WJC_METTL3_EV_vs_WT_F02.20166.20166.3 1.54E-06 17/48 R.LGIEGLSLHNVLK[136.11].L sp|Q9NYU2|UGGG1_HUMAN 1 1399.8278 0.11 19206 20166 3 1399.826814 467.6166 UDP-glucose:glycoprotein glucosyltransferase 1 OS=Homo sapiens OX=9606 GN=UGGT1 PE=1 SV=3 6.75 3491.8 - 478681 - - - -0.7401 - 3.294 0.464 - 369.6 1 2 0 -0.001 13 0 0 0 6.12E+06 5.76E+07 - - - 6.945 0.9997 221125_WJC_METTL3_EV_vs_WT_F02.20167.20167.3 0.00118 Nov-40 R.FTVWLHGVLDK[136.11].L "sp|Q6PJT7|ZC3HE_HUMAN,tr|G3V3Y4|G3V3Y4_HUMAN,tr|G3V473|G3V473_HUMAN,tr|G3V256|G3V256_HUMAN,tr|G3V572|G3V572_HUMAN,tr|G3V3R9|G3V3R9_HUMAN,tr|G3V240|G3V240_HUMAN,tr|A0A3B3IT62|A0A3B3IT62_HUMAN" 8 1321.7274 1.2 19207 20167 3 1321.725126 441.5831 Zinc finger CCCH domain-containing protein 14 OS=Homo sapiens OX=9606 GN=ZC3H14 PE=1 SV=1 6.74 3491.9 - 431083 - - - -1.7265 - 2.15 0.352 - 102 1 2 0 -0.0023 11 0 0 0 1.05E+07 8.79E+06 - - - 4.6384 0.9999 221125_WJC_METTL3_EV_vs_WT_F02.20170.20170.2 5.01E-08 14/26 K.VGEIFSAAGAAFTK[136.11].L "sp|Q8IXM2|BAP18_HUMAN,tr|H0YIS7|H0YIS7_HUMAN,tr|F8W038|F8W038_HUMAN" 3 1375.7227 1.32 19208 20170 2 1375.722302 688.8686 Chromatin complexes subunit BAP18 OS=Homo sapiens OX=9606 GN=BAP18 PE=1 SV=1 5.97 3492.3 - 7.44E+06 - - - -0.3009 - 2.912 0.54 - 715.1 1 2 0 -0.0004 14 0 0 0 1.25E+08 9.49E+07 - - - 5.7115 0.9995 221125_WJC_METTL3_EV_vs_WT_F02.20171.20171.2 9.17E-06 18-Nov R.TTDLLTDWEK.T "sp|Q14204|DYHC1_HUMAN,tr|A0A7P0T8N2|A0A7P0T8N2_HUMAN,tr|A0A7P0T9C4|A0A7P0T9C4_HUMAN,tr|A0A7P0TBJ7|A0A7P0TBJ7_HUMAN,tr|A0A804HHY6|A0A804HHY6_HUMAN,tr|A0A7P0T9K2|A0A7P0T9K2_HUMAN,tr|A0A7P0TB64|A0A7P0TB64_HUMAN,tr|A0A2R8Y706|A0A2R8Y706_HUMAN,tr|A0A7P0T916|A0A7P0T916_HUMAN,tr|A0A7P0TB75|A0A7P0TB75_HUMAN,tr|A0A7P0T8W5|A0A7P0T8W5_HUMAN,tr|A0A7P0T9S3|A0A7P0T9S3_HUMAN,tr|A0A7P0TAF3|A0A7P0TAF3_HUMAN,tr|A0A7P0T9F1|A0A7P0T9F1_HUMAN,tr|A0A7P0TAW9|A0A7P0TAW9_HUMAN,tr|A0A2R8YGC7|A0A2R8YGC7_HUMAN,tr|A0A7P0TA13|A0A7P0TA13_HUMAN,tr|A0A7P0T934|A0A7P0T934_HUMAN,tr|A0A7P0TAV5|A0A7P0TAV5_HUMAN,tr|A0A7P0T9Y3|A0A7P0T9Y3_HUMAN,tr|A0A7P0T7V5|A0A7P0T7V5_HUMAN,tr|A0A7P0T9R4|A0A7P0T9R4_HUMAN,tr|A0A2R8Y5T0|A0A2R8Y5T0_HUMAN,tr|A0A7P0T990|A0A7P0T990_HUMAN,tr|A0A7P0T942|A0A7P0T942_HUMAN,tr|A0A2R8YFZ7|A0A2R8YFZ7_HUMAN,tr|A0A7P0T825|A0A7P0T825_HUMAN,tr|A0A2R8Y6H2|A0A2R8Y6H2_HUMAN,tr|A0A7P0TAM4|A0A7P0TAM4_HUMAN" 29 1220.5925 0.95 19209 20171 2 1220.595562 611.3035 Cytoplasmic dynein 1 heavy chain 1 OS=Homo sapiens OX=9606 GN=DYNC1H1 PE=1 SV=5 4.03 3492.3 - 2.97E+06 - - - 2.5217 - 1.901 0.506 - 400.5 1 2 0 0.0031 10 0 0 0 2.98E+07 3.15E+07 - - - 4.5704 0.9999 221125_WJC_METTL3_EV_vs_WT_F02.20173.20173.2 3.42E-06 24-Dec K.GFNLNPLNQDELK.A sp|Q9NUG6|PDRG1_HUMAN 1 1500.7573 2.76 19211 20173 2 1500.756148 751.3859 p53 and DNA damage-regulated protein 1 OS=Homo sapiens OX=9606 GN=PDRG1 PE=1 SV=2 4.37 3492.5 - 2.03E+06 - - - -0.739 - 2.382 0.508 - 376 1 2 0 -0.0011 13 0 0 0 3.77E+07 1.36E+07 - - - 5.0203 0.9997 221125_WJC_METTL3_EV_vs_WT_F02.20174.20174.2 0.000192 16-Oct K.QDSGHLDLR[166.11].N "sp|Q86U44|MTA70_HUMAN,tr|B4E349|B4E349_HUMAN,tr|F5H6D8|F5H6D8_HUMAN,tr|B4DTN4|B4DTN4_HUMAN" 4 1049.5129 0.01 19212 20174 2 1049.513702 525.7637 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 5.21 3492.6 - 1.48E+06 - - - 0.7251 - 2.015 0.372 - 340 1 2 0 0.0008 9 0 0 0 2.16E+05 1.80E+07 - - - 3.8153 1 221125_WJC_METTL3_EV_vs_WT_F02.20176.20176.3 4.00E-06 15/52 K.VGEIFSAAGAAFTK[136.11].L "sp|Q8IXM2|BAP18_HUMAN,tr|H0YIS7|H0YIS7_HUMAN,tr|F8W038|F8W038_HUMAN" 3 1375.7227 1.57 19214 20176 3 1375.722322 459.5815 Chromatin complexes subunit BAP18 OS=Homo sapiens OX=9606 GN=BAP18 PE=1 SV=1 5.97 3492.8 - 1.24E+06 - - - -0.2864 - 2.409 0.505 - 300.7 1 2 0 -0.0004 14 0 0 0 1.48E+07 9.46E+06 - - - 6.5067 1 221125_WJC_METTL3_EV_vs_WT_F02.20178.20178.2 5.50E-12 20/36 K.GLLSDSMTDVPVDTGVAAR.T "sp|O43399|TPD54_HUMAN,tr|A0A087WZ51|A0A087WZ51_HUMAN,tr|A0A087WYR3|A0A087WYR3_HUMAN" 3 1902.9357 1.84 19216 20178 2 1902.936173 952.4751 Tumor protein D54 OS=Homo sapiens OX=9606 GN=TPD52L2 PE=1 SV=2 3.93 3493 - 1.18E+06 - - - 0.2528 - 4.181 0.616 - 651.2 1 2 0 0.0005 19 0 0 0 1.81E+07 9.83E+06 - - - 7.1077 0.9892 221125_WJC_METTL3_EV_vs_WT_F02.20181.20181.2 0.000358 22-Nov K.EQADFALEALAK.A "sp|Q7Z406|MYH14_HUMAN,sp|P35579|MYH9_HUMAN,tr|M0QY43|M0QY43_HUMAN" 3 1304.6612 0.72 19219 20181 2 1304.654111 653.3379 Myosin-14 OS=Homo sapiens OX=9606 GN=MYH14 PE=1 SV=2 4.14 3493.4 - 576200 - - - -5.4581 - 1.997 0.321 - 424.6 1 2 0 -0.0071 12 0 0 0 3.25E+06 4.53E+06 - - - 3.2295 0.9951 221125_WJC_METTL3_EV_vs_WT_F02.20182.20182.2 0.0234 14-Jul K.QFAFVNFK.H "sp|Q9Y580|RBM7_HUMAN,tr|F5GY08|F5GY08_HUMAN,tr|I3L521|I3L521_HUMAN,tr|J3KPD3|J3KPD3_HUMAN,tr|F5GXV8|F5GXV8_HUMAN,tr|F5H606|F5H606_HUMAN" 6 999.5178 2.53 19220 20182 2 999.516385 500.7662 RNA-binding protein 7 OS=Homo sapiens OX=9606 GN=RBM7 PE=1 SV=1 8.75 3493.6 - 522466 - - - -1.4177 - 1.348 0.197 - 120.1 1 2 0 -0.0014 8 0 0 0 6.61E+06 2.61E+06 - - - 1.3962 0.9998 221125_WJC_METTL3_EV_vs_WT_F02.20183.20183.3 4.07E-05 Aug-40 R.YNVAEIVIHIR[166.11].N "sp|Q9BZD4|NUF2_HUMAN,tr|E9PKH1|E9PKH1_HUMAN,tr|B1AQT3|B1AQT3_HUMAN,tr|B1AQT4|B1AQT4_HUMAN,tr|E9PP32|E9PP32_HUMAN,tr|E9PQC4|E9PQC4_HUMAN" 6 1335.7538 1.46 19221 20183 3 1335.753142 446.2586 Kinetochore protein Nuf2 OS=Homo sapiens OX=9606 GN=NUF2 PE=1 SV=2 6.75 3493.7 - 392249 - - - -0.5233 - 1.7 0.393 - 73.5 1 2 0 -0.0007 11 0 0 0 2.47E+06 1.70E+06 - - - 4.4288 0.9379 221125_WJC_METTL3_EV_vs_WT_F02.20184.20184.2 0.00669 Oct-32 R.LAAAAAAAQSVYAFSAR.P "sp|P07203|GPX1_HUMAN,tr|A0A7I2YMD7|A0A7I2YMD7_HUMAN,tr|A0A2R8Y6B6|A0A2R8Y6B6_HUMAN,tr|A0A7I2UQ36|A0A7I2UQ36_HUMAN" 4 1637.8526 6.7 19222 20184 2 1637.851725 819.9336 Glutathione peroxidase 1 OS=Homo sapiens OX=9606 GN=GPX1 PE=1 SV=4 8.75 3493.8 - 372704 - - - -0.5068 - 1.741 0.258 - 119.8 1 1 0 -0.0008 17 0 0 0 2.72E+06 4.06E+05 - - - 2.3095 0.9996 221125_WJC_METTL3_EV_vs_WT_F02.20187.20187.2 0.00202 18-Oct R.IQELEDLLAK[136.11].E "sp|P20700|LMNB1_HUMAN,tr|E9PBF6|E9PBF6_HUMAN" 2 1178.6638 1.24 19223 20187 2 1178.665046 590.3392 Lamin-B1 OS=Homo sapiens OX=9606 GN=LMNB1 PE=1 SV=2 4.14 3494.2 - 2.59E+06 - - - 1.0537 - 2.255 0.296 - 245.4 1 2 0 0.0012 10 0 0 0 1.79E+08 1.45E+08 - - - 3.4966 0.9993 221125_WJC_METTL3_EV_vs_WT_F02.20188.20188.2 0.00186 18-Nov R.IQELEDLLAK.E "sp|P20700|LMNB1_HUMAN,tr|E9PBF6|E9PBF6_HUMAN" 2 1170.6496 1.24 19224 20188 2 1170.647378 586.3321 Lamin-B1 OS=Homo sapiens OX=9606 GN=LMNB1 PE=1 SV=2 4.14 3494.3 - 2.33E+06 - - - -1.9015 - 2.226 0.3 - 292.8 1 2 0 -0.0022 10 0 0 0 1.79E+08 1.45E+08 - - - 3.4897 0.9999 221125_WJC_METTL3_EV_vs_WT_F02.20189.20189.3 2.03E-05 16/48 K.NILFVITKPDVYK.S "sp|E9PAV3|NACAM_HUMAN,sp|Q9BZK3|NACP4_HUMAN,sp|Q13765|NACA_HUMAN,tr|A0A7I2V473|A0A7I2V473_HUMAN,tr|F8VZJ2|F8VZJ2_HUMAN,tr|F8VNW4|F8VNW4_HUMAN,tr|A0A7I2V2K5|A0A7I2V2K5_HUMAN,tr|F8W0W4|F8W0W4_HUMAN,tr|H0YHX9|H0YHX9_HUMAN,tr|F8VZ58|F8VZ58_HUMAN" 10 1548.8916 0.32 19225 20189 3 1548.895125 517.3045 "Nascent polypeptide-associated complex subunit alpha, muscle-specific form OS=Homo sapiens OX=9606 GN=NACA PE=1 SV=1" 8.5 3494.3 - 8.05E+06 - - - 2.2978 - 2.717 0.492 - 307.2 1 2 0 0.0036 13 0 0 0 7.74E+07 2.40E+08 - - - 6.7343 0.9986 221125_WJC_METTL3_EV_vs_WT_F02.20190.20190.2 3.60E-07 20-Nov K.GFAFVQYVNER[166.11].N "sp|P07910|HNRPC_HUMAN,tr|G3V251|G3V251_HUMAN,tr|B4DY08|B4DY08_HUMAN,tr|G3V575|G3V575_HUMAN,tr|B4DSU6|B4DSU6_HUMAN,tr|G3V3K6|G3V3K6_HUMAN,tr|B2R5W2|B2R5W2_HUMAN,tr|G3V4C1|G3V4C1_HUMAN,tr|G3V576|G3V576_HUMAN,tr|G3V5X6|G3V5X6_HUMAN,tr|G3V4W0|G3V4W0_HUMAN,tr|G3V555|G3V555_HUMAN,tr|G3V4M8|G3V4M8_HUMAN,tr|G3V2Q1|G3V2Q1_HUMAN" 14 1338.6596 1.36 19226 20190 2 1338.660965 670.3371 Heterogeneous nuclear ribonucleoproteins C1\C2 OS=Homo sapiens OX=9606 GN=HNRNPC PE=1 SV=4 6 3494.4 - 1.98E+06 - - - 1.0152 - 2.423 0.123 - 583.8 1 2 0 0.0014 11 0 0 0 8.93E+08 6.59E+08 - - - 2.3432 1 221125_WJC_METTL3_EV_vs_WT_F02.20191.20191.2 4.20E-13 18/26 K.VPDNYGDEIAIELR.S sp|Q92900|RENT1_HUMAN 1 1602.789 0.99 19227 20191 2 1602.789987 802.4018 Regulator of nonsense transcripts 1 OS=Homo sapiens OX=9606 GN=UPF1 PE=1 SV=2 3.92 3494.4 - 1.76E+06 - - - 0.6457 - 3.146 0.632 - 1303.6 1 2 0 0.001 14 0 0 0 2.83E+07 2.85E+07 - - - 6.5848 0.9643 221125_WJC_METTL3_EV_vs_WT_F02.20197.20197.3 0.000242 13/44 H.IISELILTAQER.D sp|Q96I24|FUBP3_HUMAN 1 1384.7926 2.18 19233 20197 3 1384.795847 462.6048 Far upstream element-binding protein 3 OS=Homo sapiens OX=9606 GN=FUBP3 PE=1 SV=2 4.53 3495.1 - 892603 - - - 2.3592 - 2.163 0.375 - 284 1 1 0 0.0033 12 0 0 0 6.33E+06 2.90E+06 - - - 4.8584 1 221125_WJC_METTL3_EV_vs_WT_F02.20200.20200.2 6.71E-07 15/26 R.TPEILTVNSIGQLK[136.11].L sp|Q8NFH3|NUP43_HUMAN 1 1519.8701 1.71 19236 20200 2 1519.868699 760.9423 Nucleoporin Nup43 OS=Homo sapiens OX=9606 GN=NUP43 PE=1 SV=1 5.66 3495.5 - 546649 - - - -0.9277 - 2.603 0.615 - 796.8 1 2 0 -0.0014 14 0 0 0 1.97E+07 1.15E+07 - - - 5.9836 0.9991 221125_WJC_METTL3_EV_vs_WT_F02.20203.20203.3 0.0105 Oct-40 K.NLIDAGVDALR[166.11].V "sp|P12268|IMDH2_HUMAN,tr|A0A7I2YQK5|A0A7I2YQK5_HUMAN,tr|H0Y4R1|H0Y4R1_HUMAN,tr|A0A7I2V2T3|A0A7I2V2T3_HUMAN,tr|E7ETK5|E7ETK5_HUMAN" 5 1165.6331 2.04 19239 20203 3 1165.629615 389.5516 Inosine-5'-monophosphate dehydrogenase 2 OS=Homo sapiens OX=9606 GN=IMPDH2 PE=1 SV=2 4.21 3495.9 - 322713 - - - -2.9529 - 1.917 0.359 - 126.1 1 2 0 -0.0034 11 0 0 0 2.75E+06 1.35E+06 - - - 4.3902 0.9999 221125_WJC_METTL3_EV_vs_WT_F02.20206.20206.2 5.34E-07 22-Nov R.TLNNQFASFIDK.V sp|Q8N1N4|K2C78_HUMAN 1 1396.6987 14.67 19241 20206 2 1396.700302 699.3566 "Keratin, type II cytoskeletal 78 OS=Homo sapiens OX=9606 GN=KRT78 PE=1 SV=2" 5.5 3496.2 - 2.92E+06 - - - 1.1613 - 2.357 0.566 - 345.6 1 2 0 0.0016 12 0 0 0 5.75E+07 3.92E+06 - - - 5.4769 0.9994 221125_WJC_METTL3_EV_vs_WT_F02.20208.20208.2 5.62E-05 18-Sep R.ISEQFTAMFR.R "sp|P04350|TBB4A_HUMAN,sp|Q9BVA1|TBB2B_HUMAN,sp|P07437|TBB5_HUMAN,sp|Q13509|TBB3_HUMAN,sp|Q13885|TBB2A_HUMAN,sp|P68371|TBB4B_HUMAN,tr|A0A0B4J269|A0A0B4J269_HUMAN,tr|Q5ST81|Q5ST81_HUMAN,tr|Q5JP53|Q5JP53_HUMAN" 9 1228.591 0.64 19243 20208 2 1228.594183 615.3028 Tubulin beta-4A chain OS=Homo sapiens OX=9606 GN=TUBB4A PE=1 SV=2 6 3496.2 - 6.73E+06 - - - 2.555 - 1.834 0.468 - 290.6 1 2 0 0.0031 10 0 0 0 1.79E+08 2.82E+08 - - - 4.1896 0.9999 221125_WJC_METTL3_EV_vs_WT_F02.20211.20211.3 9.64E-05 Dec-56 K.ILAQVVGDVDTSLPR[166.11].T sp|Q15029|U5S1_HUMAN 1 1591.8809 4.48 19246 20211 3 1591.882395 531.6342 116 kDa U5 small nuclear ribonucleoprotein component OS=Homo sapiens OX=9606 GN=EFTUD2 PE=1 SV=1 4.21 3496.4 - 1.83E+06 - - - 0.9442 - 2.626 0.413 - 269.2 1 2 0 0.0015 15 0 0 0 1.50E+08 3.34E+07 - - - 5.6634 0.9974 221125_WJC_METTL3_EV_vs_WT_F02.20213.20213.3 0.0813 Nov-48 R.LGIEGLSLHNVLK.L sp|Q9NYU2|UGGG1_HUMAN 1 1391.8137 0.11 19248 20213 3 1391.814954 464.9452 UDP-glucose:glycoprotein glucosyltransferase 1 OS=Homo sapiens OX=9606 GN=UGGT1 PE=1 SV=3 6.75 3496.6 - 761210 - - - 0.9369 - 1.894 0.218 - 103.6 1 2 0 0.0013 13 0 0 0 6.12E+06 5.76E+07 - - - 2.7018 1 221125_WJC_METTL3_EV_vs_WT_F02.20214.20214.2 4.07E-12 16/28 K.YLLETSGNLDGLEYK.L "sp|P43490|NAMPT_HUMAN,tr|A0A7P0T862|A0A7P0T862_HUMAN,tr|B7Z8W6|B7Z8W6_HUMAN,tr|A0A7P0T931|A0A7P0T931_HUMAN,tr|A0A7P0T8L3|A0A7P0T8L3_HUMAN,tr|A0A7P0T941|A0A7P0T941_HUMAN,tr|A0A7P0T973|A0A7P0T973_HUMAN,tr|A0A7P0T895|A0A7P0T895_HUMAN,tr|A0A7P0TBB7|A0A7P0TBB7_HUMAN,tr|A0A7P0TA73|A0A7P0TA73_HUMAN,tr|A0A0C4DFS8|A0A0C4DFS8_HUMAN,tr|A0A7P0TAS5|A0A7P0TAS5_HUMAN,tr|A0A7P0T9I9|A0A7P0T9I9_HUMAN,tr|A0A7P0Z466|A0A7P0Z466_HUMAN,tr|A0A7P0T8D2|A0A7P0T8D2_HUMAN" 15 1713.8461 0.74 19249 20214 2 1713.841386 857.9303 Nicotinamide phosphoribosyltransferase OS=Homo sapiens OX=9606 GN=NAMPT PE=1 SV=1 4.14 3496.8 - 626079 - - - -2.7692 - 3.276 0.636 - 716.5 1 2 0 -0.0047 15 0 0 0 6.88E+06 9.32E+06 - - - 6.6544 0.9855 221125_WJC_METTL3_EV_vs_WT_F02.20215.20215.2 1.07E-05 22-Oct K.SIDMSWDSVTMK[136.11].H "sp|Q9UHX1|PUF60_HUMAN,tr|A0A0J9YYL3|A0A0J9YYL3_HUMAN,tr|A0A0J9YWM1|A0A0J9YWM1_HUMAN,tr|H0YEM1|H0YEM1_HUMAN,tr|E9PMU7|E9PMU7_HUMAN,tr|E9PN18|E9PN18_HUMAN,tr|E9PL19|E9PL19_HUMAN,tr|A0A0J9YVR6|A0A0J9YVR6_HUMAN,tr|A0A0J9YXX5|A0A0J9YXX5_HUMAN,tr|A0A0J9YXJ8|A0A0J9YXJ8_HUMAN,tr|E9PQ56|E9PQ56_HUMAN,tr|H0YCP8|H0YCP8_HUMAN,tr|A0A0J9YVP6|A0A0J9YVP6_HUMAN" 13 1406.6301 1 19250 20215 2 1406.619077 704.3223 Poly(U)-binding-splicing factor PUF60 OS=Homo sapiens OX=9606 GN=PUF60 PE=1 SV=1 4.21 3496.9 - 591022 - - - -7.8635 - 2.085 0.528 - 213 1 2 0 -0.0111 12 0 0 0 1.26E+07 1.26E+07 - - - 4.8706 0.9998 221125_WJC_METTL3_EV_vs_WT_F02.20216.20216.3 0.00335 Aug-36 R.DLHNLMVDLR.G sp|Q96ER9|MITOK_HUMAN 1 1224.6285 1.51 19251 20216 3 1224.627746 409.2168 Mitochondrial potassium channel OS=Homo sapiens OX=9606 GN=CCDC51 PE=1 SV=2 5.21 3497 - 309595 - - - -0.6092 - 1.647 0.43 - 95.8 1 2 0 -0.0007 10 0 0 0 2.91E+06 1.92E+06 - - - 4.791 0.9995 221125_WJC_METTL3_EV_vs_WT_F02.20217.20217.3 0.00389 Aug-36 R.DLHNLMVDLR[166.11].G sp|Q96ER9|MITOK_HUMAN 1 1234.6368 1.51 19252 20217 3 1234.637877 412.5529 Mitochondrial potassium channel OS=Homo sapiens OX=9606 GN=CCDC51 PE=1 SV=2 5.21 3497.2 - 267992 - - - 0.9031 - 1.699 0.335 - 103.5 1 2 0 0.0011 10 0 0 0 2.91E+06 1.92E+06 - - - 3.8226 0.9998 221125_WJC_METTL3_EV_vs_WT_F02.20220.20220.2 8.22E-05 28-Dec K.ILAQVVGDVDTSLPR.T sp|Q15029|U5S1_HUMAN 1 1581.8726 2.38 19253 20220 2 1581.87419 791.9436 116 kDa U5 small nuclear ribonucleoprotein component OS=Homo sapiens OX=9606 GN=EFTUD2 PE=1 SV=1 4.21 3497.5 - 4.51E+06 - - - 0.9912 - 2.584 0.465 - 391.8 1 2 0 0.0016 15 0 0 0 6.52E+07 2.74E+07 - - - 4.809 1 221125_WJC_METTL3_EV_vs_WT_F02.20221.20221.3 2.45E-08 18/52 K.AITFFTEDDK[136.11]PLLR[166.11].S "sp|Q9Y2R4|DDX52_HUMAN,tr|A0A087X121|A0A087X121_HUMAN" 2 1682.8998 11.99 19254 20221 3 1682.900577 561.9739 Probable ATP-dependent RNA helicase DDX52 OS=Homo sapiens OX=9606 GN=DDX52 PE=1 SV=3 4.56 3497.6 - 3.76E+06 - - - 0.4362 - 3.036 0.515 - 427.8 1 2 0 0.0007 14 0 0 0 3.99E+08 3.32E+07 - - - 7.2328 1 221125_WJC_METTL3_EV_vs_WT_F02.20222.20222.2 7.33E-09 13/22 R.NPPAFTELQLPR[166.11].Y "sp|Q6L8Q7|PDE12_HUMAN,tr|F6T1Q0|F6T1Q0_HUMAN" 2 1391.7437 0.97 19255 20222 2 1391.744332 696.8791 "2',5'-phosphodiesterase 12 OS=Homo sapiens OX=9606 GN=PDE12 PE=1 SV=2" 6 3497.6 - 3.21E+06 - - - 0.4757 - 2.653 0.557 - 670.5 1 2 0 0.0007 12 0 0 0 5.12E+07 5.30E+07 - - - 5.722 1 221125_WJC_METTL3_EV_vs_WT_F02.20223.20223.2 8.22E-08 22-Dec R.NPPAFTELQLPR.Y "sp|Q6L8Q7|PDE12_HUMAN,tr|F6T1Q0|F6T1Q0_HUMAN" 2 1381.7354 0.95 19256 20223 2 1381.735631 691.875 "2',5'-phosphodiesterase 12 OS=Homo sapiens OX=9606 GN=PDE12 PE=1 SV=2" 6 3497.7 - 2.59E+06 - - - 0.1672 - 2.429 0.594 - 549.6 1 2 0 0.0002 12 0 0 0 5.04E+07 5.32E+07 - - - 5.7633 1 221125_WJC_METTL3_EV_vs_WT_F02.20224.20224.2 7.11E-10 14/24 K.YAC[160.03]GLWGLSPASR.K "tr|H7C561|H7C561_HUMAN,tr|H7C0N4|H7C0N4_HUMAN" 2 1436.6871 1.27 19257 20224 2 1436.689269 719.3508 Splicing factor 1 (Fragment) OS=Homo sapiens OX=9606 GN=SF1 PE=1 SV=8 8.22 3497.8 - 1.97E+06 - - - 1.5306 - 2.737 0.601 - 657.1 1 2 0 0.0022 13 0 0 0 3.57E+07 2.81E+07 - - - 6.0634 0.9996 221125_WJC_METTL3_EV_vs_WT_F02.20225.20225.2 0.00579 16-Aug R.ILFLDPSGK[136.11].V sp|O95881|TXD12_HUMAN 1 996.5735 0.98 19258 20225 2 996.573134 499.294 Thioredoxin domain-containing protein 12 OS=Homo sapiens OX=9606 GN=TXNDC12 PE=1 SV=1 5.84 3497.8 - 1.84E+06 - - - -0.4004 - 1.723 0.377 - 140.2 1 2 0 -0.0004 9 0 0 0 1.44E+08 1.47E+08 - - - 3.3994 0.9998 221125_WJC_METTL3_EV_vs_WT_F02.20226.20226.3 6.80E-06 18/64 R.LDTHPAMVTVLEMGAAR[166.11].H "sp|Q12931|TRAP1_HUMAN,tr|I3L0K7|I3L0K7_HUMAN" 2 1820.9152 1.72 19259 20226 3 1820.90948 607.979 "Heat shock protein 75 kDa, mitochondrial OS=Homo sapiens OX=9606 GN=TRAP1 PE=1 SV=3" 5.32 3497.9 - 1.25E+06 - - - -3.166 - 2.989 0.442 - 516.3 1 2 0 -0.0058 17 0 0 0 1.84E+07 1.07E+07 - - - 6.2324 1 221125_WJC_METTL3_EV_vs_WT_F02.20229.20229.2 1.20E-08 21/32 K.VPGVTAIELDEDTGTFR.L "sp|P51114|FXR1_HUMAN,tr|E7EU85|E7EU85_HUMAN,tr|E9PFF5|E9PFF5_HUMAN,tr|B4DXZ6|B4DXZ6_HUMAN" 4 1818.9 1.21 19262 20229 2 1818.902951 910.4573 Fragile X mental retardation syndrome-related protein 1 OS=Homo sapiens OX=9606 GN=FXR1 PE=1 SV=3 3.92 3498.3 - 850311 - - - 1.645 - 3.461 0.709 - 1359.5 1 2 0 0.003 17 0 0 0 7.75E+06 6.43E+06 - - - 7.3292 0.9999 221125_WJC_METTL3_EV_vs_WT_F02.20232.20232.3 0.000176 13/40 K.GFAFVQYVNER.N "sp|P07910|HNRPC_HUMAN,tr|G3V251|G3V251_HUMAN,tr|B4DY08|B4DY08_HUMAN,tr|G3V575|G3V575_HUMAN,tr|B4DSU6|B4DSU6_HUMAN,tr|G3V3K6|G3V3K6_HUMAN,tr|B2R5W2|B2R5W2_HUMAN,tr|G3V4C1|G3V4C1_HUMAN,tr|G3V576|G3V576_HUMAN,tr|G3V5X6|G3V5X6_HUMAN,tr|G3V4W0|G3V4W0_HUMAN,tr|G3V555|G3V555_HUMAN,tr|G3V4M8|G3V4M8_HUMAN,tr|G3V2Q1|G3V2Q1_HUMAN" 14 1328.6513 1.45 19265 20232 3 1328.652716 443.8911 Heterogeneous nuclear ribonucleoproteins C1\C2 OS=Homo sapiens OX=9606 GN=HNRNPC PE=1 SV=4 6 3498.7 - 634942 - - - 1.0386 - 2.122 0.444 - 242.4 1 2 0 0.0014 11 0 0 0 1.74E+07 1.20E+07 - - - 5.6271 0.9989 221125_WJC_METTL3_EV_vs_WT_F02.20234.20234.3 9.19E-06 Dec-40 K.GFAFVQYVNER[166.11].N "sp|P07910|HNRPC_HUMAN,tr|G3V251|G3V251_HUMAN,tr|B4DY08|B4DY08_HUMAN,tr|G3V575|G3V575_HUMAN,tr|B4DSU6|B4DSU6_HUMAN,tr|G3V3K6|G3V3K6_HUMAN,tr|B2R5W2|B2R5W2_HUMAN,tr|G3V4C1|G3V4C1_HUMAN,tr|G3V576|G3V576_HUMAN,tr|G3V5X6|G3V5X6_HUMAN,tr|G3V4W0|G3V4W0_HUMAN,tr|G3V555|G3V555_HUMAN,tr|G3V4M8|G3V4M8_HUMAN,tr|G3V2Q1|G3V2Q1_HUMAN" 14 1338.6596 1.45 19267 20234 3 1338.660421 447.2271 Heterogeneous nuclear ribonucleoproteins C1\C2 OS=Homo sapiens OX=9606 GN=HNRNPC PE=1 SV=4 6 3499 - 545779 - - - 0.6088 - 2.008 0.245 - 213.7 1 2 0 0.0008 11 0 0 0 1.74E+07 1.20E+07 - - - 3.2517 0.9999 221125_WJC_METTL3_EV_vs_WT_F02.20238.20238.2 7.69E-05 24-Dec R.LSQELEYLTEDVK.R sp|P12270|TPR_HUMAN 1 1565.7825 4.35 19269 20238 2 1565.781749 783.8985 Nucleoprotein TPR OS=Homo sapiens OX=9606 GN=TPR PE=1 SV=3 4 3499.5 - 2.58E+06 - - - -0.4598 - 2.907 0.503 - 723.4 1 2 0 -0.0007 13 0 0 0 2.80E+07 6.43E+06 - - - 5.4947 1 221125_WJC_METTL3_EV_vs_WT_F02.20239.20239.2 1.92E-05 15/28 K.ILAQVVGDVDTSLPR[166.11].T sp|Q15029|U5S1_HUMAN 1 1591.8809 2.38 19270 20239 2 1591.887154 796.9477 116 kDa U5 small nuclear ribonucleoprotein component OS=Homo sapiens OX=9606 GN=EFTUD2 PE=1 SV=1 4.21 3499.6 - 2.06E+06 - - - 3.9337 - 3.126 0.585 - 863.1 1 2 0 0.0063 15 0 0 0 6.52E+07 2.74E+07 - - - 6.162 0.9998 221125_WJC_METTL3_EV_vs_WT_F02.20241.20241.2 3.24E-06 18-Oct K.QEVAVFVFDK[136.11].K "sp|Q6P3W7|SCYL2_HUMAN,tr|F8VSC5|F8VSC5_HUMAN,tr|A0A0U1RQQ9|A0A0U1RQQ9_HUMAN" 3 1188.627 1.44 19272 20241 2 1188.628196 595.3208 SCY1-like protein 2 OS=Homo sapiens OX=9606 GN=SCYL2 PE=1 SV=1 4.37 3499.7 - 2.14E+06 - - - 0.9852 - 2.07 0.491 - 345 1 2 0 0.0012 10 0 0 0 2.65E+07 1.83E+07 - - - 4.698 0.9993 221125_WJC_METTL3_EV_vs_WT_F02.20242.20242.3 1.00E-08 15/76 K.GNPQGFNQGLDC[160.03]DVIVAEVR[166.11].S sp|Q86U44|MTA70_HUMAN 1 2197.0461 0.02 19273 20242 3 2198.047453 733.356 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 4.03 3499.8 - 1.61E+06 - - - 455.756 - 2.985 0.529 - 231.8 1 2 0 1.0013 20 0 0 0 2.35E+06 1.50E+08 - - - 6.8136 0.9999 221125_WJC_METTL3_EV_vs_WT_F02.20244.20244.2 2.66E-06 22-Oct K.SIDMSWDSVTMK.H "sp|Q9UHX1|PUF60_HUMAN,tr|A0A0J9YYL3|A0A0J9YYL3_HUMAN,tr|A0A0J9YWM1|A0A0J9YWM1_HUMAN,tr|H0YEM1|H0YEM1_HUMAN,tr|E9PMU7|E9PMU7_HUMAN,tr|E9PN18|E9PN18_HUMAN,tr|E9PL19|E9PL19_HUMAN,tr|A0A0J9YVR6|A0A0J9YVR6_HUMAN,tr|A0A0J9YXX5|A0A0J9YXX5_HUMAN,tr|A0A0J9YXJ8|A0A0J9YXJ8_HUMAN,tr|E9PQ56|E9PQ56_HUMAN,tr|H0YCP8|H0YCP8_HUMAN,tr|A0A0J9YVP6|A0A0J9YVP6_HUMAN" 13 1398.6159 1 19275 20244 2 1398.615512 700.3152 Poly(U)-binding-splicing factor PUF60 OS=Homo sapiens OX=9606 GN=PUF60 PE=1 SV=1 4.21 3500 - 1.39E+06 - - - -0.3046 - 1.819 0.531 - 232.3 1 2 0 -0.0004 12 0 0 0 1.26E+07 1.26E+07 - - - 4.537 0.9999 221125_WJC_METTL3_EV_vs_WT_F02.20245.20245.2 3.65E-06 14/26 R.AGASISTLAGLSLK[136.11].E "sp|Q9UJW0|DCTN4_HUMAN,tr|E5RK21|E5RK21_HUMAN" 2 1295.754 1.58 19276 20245 2 1295.755452 648.8843 Dynactin subunit 4 OS=Homo sapiens OX=9606 GN=DCTN4 PE=1 SV=1 8.8 3500 - 1.27E+06 - - - 1.1075 - 2.855 0.534 - 719 1 2 0 0.0014 14 0 0 0 1.84E+07 1.17E+07 - - - 5.6173 0.9991 221125_WJC_METTL3_EV_vs_WT_F02.20249.20249.2 0.0514 14-Nov R.EMVLEIIR[166.11].E "sp|Q96I24|FUBP3_HUMAN,sp|Q96AE4|FUBP1_HUMAN,tr|E9PEB5|E9PEB5_HUMAN" 3 1011.5662 1.94 19280 20249 2 1011.566667 506.7904 Far upstream element-binding protein 3 OS=Homo sapiens OX=9606 GN=FUBP3 PE=1 SV=2 4.53 3500.5 - 852160 - - - 0.4389 - 2.062 0.174 - 510.1 1 2 0 0.0004 8 0 0 0 2.12E+07 1.09E+07 - - - 2.5086 1 221125_WJC_METTL3_EV_vs_WT_F02.20250.20250.2 1.18E-11 19/32 K.VPGVTAIELDEDTGTFR[166.11].L "sp|P51114|FXR1_HUMAN,tr|E7EU85|E7EU85_HUMAN,tr|E9PFF5|E9PFF5_HUMAN,tr|B4DXZ6|B4DXZ6_HUMAN" 4 1828.9082 1.21 19281 20250 2 1828.907083 915.4614 Fragile X mental retardation syndrome-related protein 1 OS=Homo sapiens OX=9606 GN=FXR1 PE=1 SV=3 3.92 3500.7 - 749883 - - - -0.6266 - 3.472 0.693 - 1121.5 1 2 0 -0.0011 17 0 0 0 7.75E+06 6.43E+06 - - - 7.2194 1 221125_WJC_METTL3_EV_vs_WT_F02.20254.20254.2 2.63E-11 21/36 R.LISLTDENALSGNEELTVK[136.11].L "sp|P14625|ENPL_HUMAN,tr|A0A7P0T917|A0A7P0T917_HUMAN,tr|A0A7P0Z405|A0A7P0Z405_HUMAN,tr|A0A7P0T823|A0A7P0T823_HUMAN,tr|A0A7P0TAE1|A0A7P0TAE1_HUMAN,tr|H0YIV0|H0YIV0_HUMAN,tr|A0A7P0T8R3|A0A7P0T8R3_HUMAN,tr|A0A7P0T885|A0A7P0T885_HUMAN,tr|A0A7P0TAY2|A0A7P0TAY2_HUMAN,tr|A0A087WT78|A0A087WT78_HUMAN,tr|A0A7P0TBC2|A0A7P0TBC2_HUMAN,tr|A0A7P0TAT8|A0A7P0TAT8_HUMAN" 12 2053.067 0.96 19285 20254 2 2053.059842 1027.5408 Endoplasmin OS=Homo sapiens OX=9606 GN=HSP90B1 PE=1 SV=1 4 3501.2 - 568559 - - - -3.5016 - 3.938 0.663 - 1345.2 1 2 0 -0.0072 19 0 0 0 7.87E+06 8.20E+06 - - - 7.3055 1 221125_WJC_METTL3_EV_vs_WT_F02.20255.20255.2 9.49E-13 19/36 R.LISLTDENALSGNEELTVK.L "sp|P14625|ENPL_HUMAN,tr|A0A7P0T917|A0A7P0T917_HUMAN,tr|A0A7P0Z405|A0A7P0Z405_HUMAN,tr|A0A7P0T823|A0A7P0T823_HUMAN,tr|A0A7P0TAE1|A0A7P0TAE1_HUMAN,tr|H0YIV0|H0YIV0_HUMAN,tr|A0A7P0T8R3|A0A7P0T8R3_HUMAN,tr|A0A7P0T885|A0A7P0T885_HUMAN,tr|A0A7P0TAY2|A0A7P0TAY2_HUMAN,tr|A0A087WT78|A0A087WT78_HUMAN,tr|A0A7P0TBC2|A0A7P0TBC2_HUMAN,tr|A0A7P0TAT8|A0A7P0TAT8_HUMAN" 12 2045.0528 0.85 19286 20255 2 2045.053467 1023.5337 Endoplasmin OS=Homo sapiens OX=9606 GN=HSP90B1 PE=1 SV=1 4 3501.3 - 538291 - - - 0.311 - 3.846 0.724 - 1011.2 1 2 0 0.0006 19 0 0 0 6.98E+06 8.20E+06 - - - 7.7 0.9998 221125_WJC_METTL3_EV_vs_WT_F02.20261.20261.2 2.33E-05 16-Aug R.DWNTLIVGK.L "sp|O14744|ANM5_HUMAN,tr|C9JSX3|C9JSX3_HUMAN,tr|G3V580|G3V580_HUMAN,tr|G3V2L6|G3V2L6_HUMAN,tr|G3V2X6|G3V2X6_HUMAN,tr|G3V5L5|G3V5L5_HUMAN" 6 1044.5604 2.47 19290 20261 2 1044.560279 523.2875 Protein arginine N-methyltransferase 5 OS=Homo sapiens OX=9606 GN=PRMT5 PE=1 SV=4 5.84 3502.1 - 2.85E+07 - - - -0.1111 - 1.838 0.457 - 233.9 1 2 0 -0.0001 9 0 0 0 1.22E+09 4.94E+08 - - - 4.1773 1 221125_WJC_METTL3_EV_vs_WT_F02.20262.20262.2 3.30E-08 14/30 R.IINEPTAAAIAYGLDK.R "sp|P11021|BIP_HUMAN,sp|P54652|HSP72_HUMAN,sp|P34931|HS71L_HUMAN,sp|P11142|HSP7C_HUMAN,tr|E9PKE3|E9PKE3_HUMAN,tr|E9PN89|E9PN89_HUMAN,tr|A0A7P0TB36|A0A7P0TB36_HUMAN,tr|E9PLF4|E9PLF4_HUMAN,tr|A0A7P0TAI0|A0A7P0TAI0_HUMAN,tr|Q53FA3|Q53FA3_HUMAN,tr|E9PI65|E9PI65_HUMAN" 11 1658.8879 0.2 19291 20262 2 1658.887454 830.4512 Endoplasmic reticulum chaperone BiP OS=Homo sapiens OX=9606 GN=HSPA5 PE=1 SV=2 4.37 3502.1 - 2.45E+07 - - - -0.2912 - 3.122 0.639 - 613.1 1 2 0 -0.0005 16 0 0 0 5.36E+08 2.67E+09 - - - 6.5595 1 221125_WJC_METTL3_EV_vs_WT_F02.20263.20263.2 8.01E-06 20-Oct K.SNNVEMDWVLK.H "sp|P31943|HNRH1_HUMAN,tr|E5RGH4|E5RGH4_HUMAN,tr|E7EQJ0|E7EQJ0_HUMAN,tr|D6RIH9|D6RIH9_HUMAN,tr|D6RJ04|D6RJ04_HUMAN,tr|E5RGV0|E5RGV0_HUMAN,tr|D6RFM3|D6RFM3_HUMAN,tr|E9PCY7|E9PCY7_HUMAN,tr|D6RIT2|D6RIT2_HUMAN,tr|D6R9T0|D6R9T0_HUMAN,tr|D6RIU0|D6RIU0_HUMAN,tr|H0YAQ2|H0YAQ2_HUMAN,tr|D6RAM1|D6RAM1_HUMAN,tr|D6RBM0|D6RBM0_HUMAN,tr|G8JLB6|G8JLB6_HUMAN,tr|D6RDU3|D6RDU3_HUMAN" 16 1333.6336 1.23 19292 20263 2 1333.633383 667.8241 Heterogeneous nuclear ribonucleoprotein H OS=Homo sapiens OX=9606 GN=HNRNPH1 PE=1 SV=4 4.37 3502.1 - 1.49E+07 - - - -0.1905 - 2.303 0.603 - 363.5 1 2 0 -0.0003 11 0 0 0 4.28E+08 3.48E+08 - - - 5.7514 1 221125_WJC_METTL3_EV_vs_WT_F02.20264.20264.3 1.01E-07 18/60 R.IINEPTAAAIAYGLDK.R "sp|P11021|BIP_HUMAN,sp|P54652|HSP72_HUMAN,sp|P34931|HS71L_HUMAN,sp|P11142|HSP7C_HUMAN,tr|E9PKE3|E9PKE3_HUMAN,tr|E9PN89|E9PN89_HUMAN,tr|A0A7P0TB36|A0A7P0TB36_HUMAN,tr|E9PLF4|E9PLF4_HUMAN,tr|A0A7P0TAI0|A0A7P0TAI0_HUMAN,tr|Q53FA3|Q53FA3_HUMAN,tr|E9PI65|E9PI65_HUMAN" 11 1658.8879 0.2 19293 20264 3 1658.889037 553.9699 Endoplasmic reticulum chaperone BiP OS=Homo sapiens OX=9606 GN=HSPA5 PE=1 SV=2 4.37 3502.2 - 1.43E+07 - - - 0.6631 - 3.477 0.61 - 511.8 1 2 0 0.0011 16 0 0 0 2.69E+08 1.37E+09 - - - 8.5381 0.9997 221125_WJC_METTL3_EV_vs_WT_F02.20265.20265.2 0.00169 16-Sep R.ILFLDPSGK.V sp|O95881|TXD12_HUMAN 1 988.5593 0.98 19294 20265 2 988.558622 495.2869 Thioredoxin domain-containing protein 12 OS=Homo sapiens OX=9606 GN=TXNDC12 PE=1 SV=1 5.84 3502.2 - 5.74E+06 - - - -0.7192 - 1.673 0.415 - 227.2 1 2 0 -0.0007 9 0 0 0 1.44E+08 1.47E+08 - - - 3.5948 1 221125_WJC_METTL3_EV_vs_WT_F02.20269.20269.2 6.12E-07 15/24 R.DANLTALAAIGPR.K "sp|Q92750|TAF4B_HUMAN,sp|O00268|TAF4_HUMAN,tr|A0A0G2JRY5|A0A0G2JRY5_HUMAN,tr|V9GY03|V9GY03_HUMAN,tr|J3KTH2|J3KTH2_HUMAN" 5 1281.7041 2.17 19298 20269 2 1281.703377 641.8593 Transcription initiation factor TFIID subunit 4B OS=Homo sapiens OX=9606 GN=TAF4B PE=1 SV=2 5.84 3502.6 - 1.48E+06 - - - -0.5641 - 3.072 0.57 - 975.8 1 2 0 -0.0007 13 0 0 0 5.99E+07 2.76E+07 - - - 6.1313 0.9999 221125_WJC_METTL3_EV_vs_WT_F02.20271.20271.2 1.99E-06 14/24 R.SVDVILDDDLVDK.A "sp|P25205|MCM3_HUMAN,tr|J3KQ69|J3KQ69_HUMAN,tr|A0A499FHX9|A0A499FHX9_HUMAN" 3 1444.7297 0.58 19300 20271 2 1444.728653 723.3721 DNA replication licensing factor MCM3 OS=Homo sapiens OX=9606 GN=MCM3 PE=1 SV=3 3.66 3502.8 - 1.30E+06 - - - -0.7282 - 2.78 0.509 - 660.6 1 2 0 -0.0011 13 0 0 0 3.27E+07 5.64E+07 - - - 5.4243 1 221125_WJC_METTL3_EV_vs_WT_F02.20277.20277.2 1.49E-11 15/32 R.LYLEDDDPVQAEAYINR.A "sp|Q9BT78|CSN4_HUMAN,tr|D6RD63|D6RD63_HUMAN,tr|D6RFN0|D6RFN0_HUMAN,tr|D6RAX7|D6RAX7_HUMAN" 4 2022.9535 0.73 19306 20277 2 2022.950569 1012.484 COP9 signalosome complex subunit 4 OS=Homo sapiens OX=9606 GN=COPS4 PE=1 SV=1 3.77 3503.6 - 426690 - - - -1.4246 - 3.197 0.703 - 638.6 1 2 0 -0.0029 17 0 0 0 2.04E+06 2.79E+06 - - - 7.0898 0.9997 221125_WJC_METTL3_EV_vs_WT_F02.20279.20279.2 0.00363 18-Oct R.NMQDLVEDLK.N "sp|P48668|K2C6C_HUMAN,sp|P04259|K2C6B_HUMAN" 2 1203.5805 39.63 19307 20279 2 1203.580416 602.7975 "Keratin, type II cytoskeletal 6C OS=Homo sapiens OX=9606 GN=KRT6C PE=1 SV=3" 4.03 3503.8 - 1.24E+07 - - - -0.1022 - 2.01 0.369 - 448.6 1 2 0 -0.0001 10 0 0 0 8.37E+08 2.11E+07 - - - 3.7151 0.9998 221125_WJC_METTL3_EV_vs_WT_F02.20280.20280.2 0.0425 14/20 K.LALDVEIATYR.K "sp|P48668|K2C6C_HUMAN,sp|Q01546|K22O_HUMAN,sp|P12035|K2C3_HUMAN,sp|P04259|K2C6B_HUMAN,sp|P13647|K2C5_HUMAN,sp|P35908|K22E_HUMAN,sp|O95678|K2C75_HUMAN,sp|Q5XKE5|K2C79_HUMAN,sp|P02538|K2C6A_HUMAN,tr|H0YI76|H0YI76_HUMAN,tr|H0YID6|H0YID6_HUMAN" 11 1262.6871 999 19308 20280 2 1262.687131 632.3508 "Keratin, type II cytoskeletal 6C OS=Homo sapiens OX=9606 GN=KRT6C PE=1 SV=3" 4.37 3503.8 - 1.19E+07 - - - 0.0618 - 2.813 0.313 - 975.4 1 2 0 0.0001 11 0 0 0 1.97E+08 0.00E+00 - - - 4.1507 1 221125_WJC_METTL3_EV_vs_WT_F02.20281.20281.2 2.26E-08 14/30 R.IINEPTAAAIAYGLDK[136.11].R "sp|P11021|BIP_HUMAN,sp|P54652|HSP72_HUMAN,sp|P34931|HS71L_HUMAN,sp|P11142|HSP7C_HUMAN,tr|E9PKE3|E9PKE3_HUMAN,tr|E9PN89|E9PN89_HUMAN,tr|A0A7P0TB36|A0A7P0TB36_HUMAN,tr|E9PLF4|E9PLF4_HUMAN,tr|A0A7P0TAI0|A0A7P0TAI0_HUMAN,tr|Q53FA3|Q53FA3_HUMAN,tr|E9PI65|E9PI65_HUMAN" 11 1666.9021 0.2 19309 20281 2 1666.899604 834.4583 Endoplasmic reticulum chaperone BiP OS=Homo sapiens OX=9606 GN=HSPA5 PE=1 SV=2 4.37 3503.9 - 2.59E+08 - - - -1.5196 - 2.973 0.618 - 567.5 1 2 0 -0.0025 16 0 0 0 5.34E+08 2.67E+09 - - - 6.2835 0.9999 221125_WJC_METTL3_EV_vs_WT_F02.20282.20282.2 1.86E-05 16-Oct R.DWNTLIVGK[136.11].L "sp|O14744|ANM5_HUMAN,tr|C9JSX3|C9JSX3_HUMAN,tr|G3V580|G3V580_HUMAN,tr|G3V2L6|G3V2L6_HUMAN,tr|G3V2X6|G3V2X6_HUMAN,tr|G3V5L5|G3V5L5_HUMAN" 6 1052.5746 2.43 19310 20282 2 1052.573977 527.2946 Protein arginine N-methyltransferase 5 OS=Homo sapiens OX=9606 GN=PRMT5 PE=1 SV=4 5.84 3503.9 - 2.98E+07 - - - -0.5871 - 2.059 0.561 - 394 1 2 0 -0.0006 9 0 0 0 1.22E+09 5.02E+08 - - - 5.2738 0.9998 221125_WJC_METTL3_EV_vs_WT_F02.20283.20283.2 2.01E-07 18-Oct K.FQMAYSNLLR.A sp|P37108|SRP14_HUMAN 1 1241.6227 0.96 19311 20283 2 1241.621133 621.8186 Signal recognition particle 14 kDa protein OS=Homo sapiens OX=9606 GN=SRP14 PE=1 SV=2 8.75 3503.9 - 1.52E+07 - - - -1.2443 - 2.07 0.505 - 324.4 1 2 0 -0.0015 10 0 0 0 1.11E+08 1.15E+08 - - - 4.8013 0.7853 221125_WJC_METTL3_EV_vs_WT_F02.20285.20285.2 0.181 22-Jun K.GSLGGGFSSGGF.S "sp|P13645|K1C10_HUMAN,tr|A0A1B0GVI3|A0A1B0GVI3_HUMAN" 2 1028.4563 - 19313 20285 2 1028.455994 515.2354 "Keratin, type I cytoskeletal 10 OS=Homo sapiens OX=9606 GN=KRT10 PE=1 SV=6" 5.52 3504 - 7.34E+06 - - - -0.3209 - 1.213 0.22 - 70.2 1 1 0 -0.0003 12 0 0 0 - - - - - 1.1739 0.9996 221125_WJC_METTL3_EV_vs_WT_F02.20286.20286.2 0.00808 16-Oct K.TFLEFYEEK[136.11].L "sp|O43148|MCES_HUMAN,tr|K7EP06|K7EP06_HUMAN" 2 1212.5794 1.02 19314 20286 2 1212.58063 607.297 mRNA cap guanine-N7 methyltransferase OS=Homo sapiens OX=9606 GN=RNMT PE=1 SV=1 4.25 3504.1 - 3.44E+06 - - - 1.0094 - 1.718 0.385 - 280.5 1 2 0 0.0012 9 0 0 0 2.64E+07 2.60E+07 - - - 3.4498 0.8611 221125_WJC_METTL3_EV_vs_WT_F02.20289.20289.2 4.50E-06 30-Dec K.IFVGGLSVNTTVEDVK[136.11].Q "sp|O43347|MSI1H_HUMAN,tr|H0YHB7|H0YHB7_HUMAN" 2 1684.9127 1.38 19317 20289 2 1684.899319 843.4636 RNA-binding protein Musashi homolog 1 OS=Homo sapiens OX=9606 GN=MSI1 PE=1 SV=1 4.37 3504.3 - 2.08E+06 - - - -7.9428 - 2.01 0.191 - 228.6 1 2 0 -0.0134 16 0 0 0 4.52E+08 3.27E+08 - - - 2.1639 1 221125_WJC_METTL3_EV_vs_WT_F02.20290.20290.3 3.48E-12 25/76 K.PVTTPEEIAQVATISANGDK.E "sp|P10809|CH60_HUMAN,tr|A0A7I2V599|A0A7I2V599_HUMAN,tr|E7EXB4|E7EXB4_HUMAN,tr|A0A7I2YQ71|A0A7I2YQ71_HUMAN,tr|E7ESH4|E7ESH4_HUMAN,tr|A0A7I2V5M1|A0A7I2V5M1_HUMAN,tr|A0A7I2V5K3|A0A7I2V5K3_HUMAN,tr|A0A7I2V369|A0A7I2V369_HUMAN" 8 2040.0375 1.32 19318 20290 3 2040.043402 681.0198 "60 kDa heat shock protein, mitochondrial OS=Homo sapiens OX=9606 GN=HSPD1 PE=1 SV=2" 4.14 3504.3 - 2.00E+06 - - - 2.8857 - 4.678 0.608 - 594 1 1 0 0.0059 20 0 0 0 4.20E+07 3.17E+07 - - - 9.06 0.9983 221125_WJC_METTL3_EV_vs_WT_F02.20294.20294.3 0.232 Dec-40 R.LLLIQAFR[166.11]PDR[166.11].L "sp|Q14204|DYHC1_HUMAN,tr|A0A7P0T8N2|A0A7P0T8N2_HUMAN,tr|A0A7P0T9C4|A0A7P0T9C4_HUMAN,tr|A0A7P0TBJ7|A0A7P0TBJ7_HUMAN,tr|A0A2R8Y706|A0A2R8Y706_HUMAN,tr|A0A7P0T916|A0A7P0T916_HUMAN,tr|A0A7P0TAW9|A0A7P0TAW9_HUMAN,tr|A0A7P0TA13|A0A7P0TA13_HUMAN,tr|A0A7P0T7V5|A0A7P0T7V5_HUMAN,tr|A0A7P0T9R4|A0A7P0T9R4_HUMAN,tr|A0A2R8Y5T0|A0A2R8Y5T0_HUMAN" 11 1360.8094 0.8 19322 20294 3 1360.807631 454.6104 Cytoplasmic dynein 1 heavy chain 1 OS=Homo sapiens OX=9606 GN=DYNC1H1 PE=1 SV=5 9.6 3504.8 - 1.02E+06 - - - -1.2963 - 1.944 0.234 - 244.1 1 2 0 -0.0018 11 0 0 0 9.13E+06 1.13E+07 - - - 3.0368 0.9999 221125_WJC_METTL3_EV_vs_WT_F02.20298.20298.2 2.73E-06 20-Oct K.SNNVEMDWVLK[136.11].H "sp|P31943|HNRH1_HUMAN,tr|E5RGH4|E5RGH4_HUMAN,tr|E7EQJ0|E7EQJ0_HUMAN,tr|D6RIH9|D6RIH9_HUMAN,tr|D6RJ04|D6RJ04_HUMAN,tr|E5RGV0|E5RGV0_HUMAN,tr|D6RFM3|D6RFM3_HUMAN,tr|E9PCY7|E9PCY7_HUMAN,tr|D6RIT2|D6RIT2_HUMAN,tr|D6R9T0|D6R9T0_HUMAN,tr|D6RIU0|D6RIU0_HUMAN,tr|H0YAQ2|H0YAQ2_HUMAN,tr|D6RAM1|D6RAM1_HUMAN,tr|D6RBM0|D6RBM0_HUMAN,tr|G8JLB6|G8JLB6_HUMAN,tr|D6RDU3|D6RDU3_HUMAN" 16 1341.6478 1.23 19324 20298 2 1341.647016 671.8312 Heterogeneous nuclear ribonucleoprotein H OS=Homo sapiens OX=9606 GN=HNRNPH1 PE=1 SV=4 4.37 3505.3 - 4.18E+07 - - - -0.6119 - 2.248 0.497 - 381.9 1 2 0 -0.0008 11 0 0 0 4.28E+08 3.48E+08 - - - 4.9029 1 221125_WJC_METTL3_EV_vs_WT_F02.20299.20299.2 6.08E-07 13/22 K.SLNNQFASFIDK.V sp|P04264|K2C1_HUMAN 1 1382.683 999 19325 20299 2 1382.680764 692.3488 "Keratin, type II cytoskeletal 1 OS=Homo sapiens OX=9606 GN=KRT1 PE=1 SV=6" 5.55 3505.4 - 7.56E+06 - - - -1.6388 - 2.517 0.629 - 531.8 1 2 0 -0.0023 12 0 0 0 2.80E+09 0.00E+00 - - - 6.1148 0.9994 221125_WJC_METTL3_EV_vs_WT_F02.20301.20301.2 0.00491 18-Sep R.YLYTLVITDK.E "sp|P63173|RL38_HUMAN,tr|J3KT73|J3KT73_HUMAN,tr|J3QL01|J3QL01_HUMAN" 3 1227.6751 1.3 19327 20301 2 1227.675815 614.8448 60S ribosomal protein L38 OS=Homo sapiens OX=9606 GN=RPL38 PE=1 SV=2 5.83 3505.5 - 4.85E+06 - - - 0.5897 - 1.624 0.35 - 184.3 1 2 0 0.0007 10 0 0 0 1.08E+08 8.34E+07 - - - 2.9794 1 221125_WJC_METTL3_EV_vs_WT_F02.20302.20302.3 1.39E-09 19/48 K.TVTAMDVVYALKR.Q sp|P62805|H4_HUMAN 1 1465.7963 0.91 19328 20302 3 1465.794953 489.606 Histone H4 OS=Homo sapiens OX=9606 GN=H4C1 PE=1 SV=2 8.25 3505.5 - 3.48E+06 - - - -0.9094 - 2.954 0.615 - 381.8 1 2 0 -0.0013 13 0 0 0 2.02E+08 2.22E+08 - - - 8.333 0.9999 221125_WJC_METTL3_EV_vs_WT_F02.20303.20303.2 0.000354 26-Dec K.AEGAALDC[160.03]FEVTLK.C sp|Q9BUA3|SPNDC_HUMAN 1 1522.7337 4.27 19329 20303 2 1522.734725 762.3741 Spindlin interactor and repressor of chromatin-binding protein OS=Homo sapiens OX=9606 GN=SPINDOC PE=1 SV=3 4.14 3505.7 - 2.79E+06 - - - 0.6436 - 2.868 0.466 - 460.2 1 2 0 0.001 14 0 0 0 9.59E+07 2.25E+07 - - - 5.1266 1 221125_WJC_METTL3_EV_vs_WT_F02.20304.20304.2 5.91E-08 16/24 R.DANLTALAAIGPR[166.11].K "sp|Q92750|TAF4B_HUMAN,sp|O00268|TAF4_HUMAN,tr|A0A0G2JRY5|A0A0G2JRY5_HUMAN,tr|V9GY03|V9GY03_HUMAN,tr|J3KTH2|J3KTH2_HUMAN" 5 1291.7124 2.17 19330 20304 2 1291.711015 646.8635 Transcription initiation factor TFIID subunit 4B OS=Homo sapiens OX=9606 GN=TAF4B PE=1 SV=2 5.84 3505.8 - 2.22E+06 - - - -1.049 - 2.981 0.596 - 896 1 2 0 -0.0014 13 0 0 0 5.99E+07 2.76E+07 - - - 6.2459 0.9998 221125_WJC_METTL3_EV_vs_WT_F02.20307.20307.2 9.05E-05 20-Dec R.YLVVLYYNANR[166.11].A sp|Q9Y3B4|SF3B6_HUMAN 1 1396.7379 1.71 19333 20307 2 1396.736049 699.3762 Splicing factor 3B subunit 6 OS=Homo sapiens OX=9606 GN=SF3B6 PE=1 SV=1 8.5 3506.2 - 1.64E+06 - - - -1.2937 - 2.338 0.478 - 619.9 1 2 0 -0.0018 11 0 0 0 3.23E+07 1.90E+07 - - - 4.8685 1 221125_WJC_METTL3_EV_vs_WT_F02.20314.20314.3 3.95E-07 14/60 R.IINEPTAAAIAYGLDK[136.11].R "sp|P11021|BIP_HUMAN,sp|P54652|HSP72_HUMAN,sp|P34931|HS71L_HUMAN,sp|P11142|HSP7C_HUMAN,tr|E9PKE3|E9PKE3_HUMAN,tr|E9PN89|E9PN89_HUMAN,tr|A0A7P0TB36|A0A7P0TB36_HUMAN,tr|E9PLF4|E9PLF4_HUMAN,tr|A0A7P0TAI0|A0A7P0TAI0_HUMAN,tr|Q53FA3|Q53FA3_HUMAN,tr|E9PI65|E9PI65_HUMAN" 11 1666.9021 0.2 19338 20314 3 1666.899874 556.6413 Endoplasmic reticulum chaperone BiP OS=Homo sapiens OX=9606 GN=HSPA5 PE=1 SV=2 4.37 3507.1 - 1.24E+08 - - - -1.3576 - 3.132 0.527 - 256.8 1 2 0 -0.0023 16 0 0 0 2.70E+08 1.37E+09 - - - 7.3443 1 221125_WJC_METTL3_EV_vs_WT_F02.20316.20316.3 7.59E-07 16/48 K.TVTAMDVVYALK[136.11]R[166.11].Q sp|P62805|H4_HUMAN 1 1483.8188 0.91 19340 20316 3 1483.818334 495.6135 Histone H4 OS=Homo sapiens OX=9606 GN=H4C1 PE=1 SV=2 8.25 3507.2 - 1.67E+07 - - - -0.2844 - 2.286 0.566 - 226.1 1 2 0 -0.0004 13 0 0 0 2.02E+08 2.22E+08 - - - 7.0919 1 221125_WJC_METTL3_EV_vs_WT_F02.20317.20317.2 7.80E-08 13/26 H.MELPYGTLTDDEMR[166.11].R sp|Q86U44|MTA70_HUMAN 1 1679.741 0.001 19341 20317 2 1679.738603 840.8778 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 3.92 3507.2 - 1.11E+07 - - - -1.4443 - 2.764 0.685 - 496.3 1 1 0 -0.0024 14 0 0 0 0.00E+00 1.20E+08 - - - 6.651 1 221125_WJC_METTL3_EV_vs_WT_F02.20319.20319.2 0.000244 16/28 K.LAAVDATVNQVLASR.Y sp|Q15084|PDIA6_HUMAN 1 1526.8417 1.39 19343 20319 2 1526.842087 764.4281 Protein disulfide-isomerase A6 OS=Homo sapiens OX=9606 GN=PDIA6 PE=1 SV=1 5.84 3507.3 - 4.55E+06 - - - 0.2823 - 3.327 0.542 - 969.1 1 2 0 0.0004 15 0 0 0 9.49E+07 6.83E+07 - - - 5.9994 0.9999 221125_WJC_METTL3_EV_vs_WT_F02.20320.20320.3 0.000628 Sep-52 K.SELVAMLEEEELRK.A "sp|P40616|ARL1_HUMAN,tr|B4DZG7|B4DZG7_HUMAN,tr|F8VYN9|F8VYN9_HUMAN" 3 1674.8498 176.15 19344 20320 3 1674.84849 559.2906 ADP-ribosylation factor-like protein 1 OS=Homo sapiens OX=9606 GN=ARL1 PE=1 SV=1 4.32 3507.4 - 8.42E+06 - - - -0.8043 - 2 0.408 - 99.7 1 2 0 -0.0013 14 0 0 0 9.00E+09 5.11E+07 - - - 4.9305 1 221125_WJC_METTL3_EV_vs_WT_F02.20321.20321.3 2.93E-10 19/56 K.LAAVDATVNQVLASR.Y sp|Q15084|PDIA6_HUMAN 1 1526.8417 1.27 19345 20321 3 1526.841609 509.9545 Protein disulfide-isomerase A6 OS=Homo sapiens OX=9606 GN=PDIA6 PE=1 SV=1 5.84 3507.4 - 2.72E+06 - - - -0.0308 - 3.603 0.582 - 498.2 1 2 0 0 15 0 0 0 4.77E+07 3.75E+07 - - - 8.3733 0.9999 221125_WJC_METTL3_EV_vs_WT_F02.20322.20322.2 0.00014 15/28 K.LSVFANGVVTSIQDR[166.11].Y sp|Q9NP61|ARFG3_HUMAN 1 1614.8605 1.1 19346 20322 2 1614.859087 808.4375 ADP-ribosylation factor GTPase-activating protein 3 OS=Homo sapiens OX=9606 GN=ARFGAP3 PE=1 SV=1 5.84 3507.5 - 2.55E+06 - - - -0.8694 - 3.109 0.506 - 808 1 2 0 -0.0014 15 0 0 0 1.33E+08 1.21E+08 - - - 5.5666 1 221125_WJC_METTL3_EV_vs_WT_F02.20327.20327.2 1.27E-06 Nov-32 R.FSSGGAC[160.03]GLGGGYGGGF.S "sp|P02533|K1C14_HUMAN,sp|P08779|K1C16_HUMAN" 2 1506.6198 - 19351 20327 2 1506.616612 754.3172 "Keratin, type I cytoskeletal 14 OS=Homo sapiens OX=9606 GN=KRT14 PE=1 SV=4" 5.52 3508 - 1.70E+06 - - - -2.1014 - 2.237 0.64 - 220.6 1 1 0 -0.0032 17 0 0 0 - - - - - 5.7465 1 221125_WJC_METTL3_EV_vs_WT_F02.20328.20328.3 4.61E-12 22/76 K.PVTTPEEIAQVATISANGDK[136.11].E "sp|P10809|CH60_HUMAN,tr|A0A7I2V599|A0A7I2V599_HUMAN,tr|E7EXB4|E7EXB4_HUMAN,tr|A0A7I2YQ71|A0A7I2YQ71_HUMAN,tr|E7ESH4|E7ESH4_HUMAN,tr|A0A7I2V5M1|A0A7I2V5M1_HUMAN,tr|A0A7I2V5K3|A0A7I2V5K3_HUMAN,tr|A0A7I2V369|A0A7I2V369_HUMAN" 8 2048.0517 1.31 19352 20328 3 2048.050232 683.6912 "60 kDa heat shock protein, mitochondrial OS=Homo sapiens OX=9606 GN=HSPD1 PE=1 SV=2" 4.14 3508.1 - 1.58E+06 - - - -0.7241 - 4.771 0.559 - 708.1 1 1 0 -0.0015 20 0 0 0 4.20E+07 3.20E+07 - - - 8.5627 0.9992 221125_WJC_METTL3_EV_vs_WT_F02.20329.20329.2 0.0609 18-Oct K.VIELQEIISK[136.11].Q "sp|Q13136|LIPA1_HUMAN,tr|H0YEF9|H0YEF9_HUMAN,tr|E9PJZ7|E9PJZ7_HUMAN,tr|A0A2R8Y7R9|A0A2R8Y7R9_HUMAN" 4 1178.7002 0.62 19353 20329 2 1178.700505 590.3574 Liprin-alpha-1 OS=Homo sapiens OX=9606 GN=PPFIA1 PE=1 SV=1 4.53 3508.3 - 1.51E+06 - - - 0.2672 - 2.051 0.205 - 236.7 1 2 0 0.0003 10 0 0 0 6.50E+06 1.05E+07 - - - 2.5601 0.9804 221125_WJC_METTL3_EV_vs_WT_F02.20330.20330.2 0.981 12-Jul K.DLDIFDR[166.11].V "sp|Q14165|MLEC_HUMAN,tr|H0YG07|H0YG07_HUMAN,tr|F5H1S8|F5H1S8_HUMAN" 3 902.4373 1.81 19354 20330 2 902.436174 452.2259 Malectin OS=Homo sapiens OX=9606 GN=MLEC PE=1 SV=1 3.93 3508.4 - 1.43E+06 - - - -1.2666 - 1.522 0 - 204.1 1 2 0 -0.0011 7 0 0 0 2.18E+07 1.20E+07 - - - 0.3715 1 221125_WJC_METTL3_EV_vs_WT_F02.20331.20331.2 2.65E-10 17/32 R.SVFVGNIPYEATEEQLK.D "sp|P33240|CSTF2_HUMAN,sp|Q9H0L4|CSTFT_HUMAN,tr|E9PID8|E9PID8_HUMAN,tr|E7EWR4|E7EWR4_HUMAN" 4 1922.9626 999 19355 20331 2 1922.958273 962.4886 Cleavage stimulation factor subunit 2 OS=Homo sapiens OX=9606 GN=CSTF2 PE=1 SV=1 4.25 3508.5 - 1.16E+06 - - - -2.2289 - 3.303 0.65 - 575.8 1 2 0 -0.0043 17 0 0 0 5.73E+06 0.00E+00 - - - 6.7781 0.9999 221125_WJC_METTL3_EV_vs_WT_F02.20332.20332.3 2.76E-07 19/56 K.LSVFANGVVTSIQDR[166.11].Y sp|Q9NP61|ARFG3_HUMAN 1 1614.8605 1.04 19356 20332 3 1614.855479 539.2941 ADP-ribosylation factor GTPase-activating protein 3 OS=Homo sapiens OX=9606 GN=ARFGAP3 PE=1 SV=1 5.84 3508.6 - 1.10E+06 - - - -3.1037 - 3.335 0.481 - 523 1 2 0 -0.005 15 0 0 0 3.33E+07 3.20E+07 - - - 7.0442 1 221125_WJC_METTL3_EV_vs_WT_F02.20333.20333.3 4.14E-05 Dec-40 K.HLNSILVLDLR[166.11].D sp|Q9H9A6|LRC40_HUMAN 1 1301.7695 1.98 19357 20333 3 1301.770462 434.9304 Leucine-rich repeat-containing protein 40 OS=Homo sapiens OX=9606 GN=LRRC40 PE=1 SV=1 6.74 3508.8 - 976800 - - - 0.7459 - 2.455 0.453 - 272.8 1 2 0 0.001 11 0 0 0 1.39E+07 7.06E+06 - - - 6.1417 0.9971 221125_WJC_METTL3_EV_vs_WT_F02.20335.20335.2 0.0645 20-Nov K.WENGTFPGWPK.E sp|Q12874|SF3A3_HUMAN 1 1317.6142 4.24 19358 20335 2 1317.616444 659.8144 Splicing factor 3A subunit 3 OS=Homo sapiens OX=9606 GN=SF3A3 PE=1 SV=1 6 3509 - 1.35E+06 - - - 1.6864 - 1.477 0.261 - 252.2 1 2 0 0.0022 11 0 0 0 1.57E+07 3.70E+06 - - - 2.0231 0.9998 221125_WJC_METTL3_EV_vs_WT_F02.20337.20337.2 0.014 14-Jul K.DVIEEYFK.C sp|P25398|RS12_HUMAN 1 1041.5019 1.83 19360 20337 2 1041.502054 521.7582 40S ribosomal protein S12 OS=Homo sapiens OX=9606 GN=RPS12 PE=1 SV=3 4.14 3509.1 - 2.04E+08 - - - 0.169 - 1.739 0.431 - 169.4 1 2 0 0.0002 8 0 0 0 2.91E+09 1.59E+09 - - - 3.8931 1 221125_WJC_METTL3_EV_vs_WT_F02.20339.20339.2 2.67E-07 13/24 R.LALGSFVEEYNNK.V "sp|P61962|DCAF7_HUMAN,tr|A0A087WWI6|A0A087WWI6_HUMAN" 2 1482.7355 1.47 19362 20339 2 1482.734147 742.375 DDB1- and CUL4-associated factor 7 OS=Homo sapiens OX=9606 GN=DCAF7 PE=1 SV=1 4.53 3509.2 - 4.66E+06 - - - -0.8849 - 2.713 0.594 - 610.1 1 2 0 -0.0013 13 0 0 0 1.48E+08 1.00E+08 - - - 5.9894 0.9999 221125_WJC_METTL3_EV_vs_WT_F02.20341.20341.2 1.98E-07 20-Nov R.FQIMNEIVYEK[136.11].L "sp|O75643|U520_HUMAN,tr|A0A494C1A5|A0A494C1A5_HUMAN" 2 1420.7152 1.62 19364 20341 2 1420.713901 711.3649 U5 small nuclear ribonucleoprotein 200 kDa helicase OS=Homo sapiens OX=9606 GN=SNRNP200 PE=1 SV=2 4.53 3509.3 - 3.64E+06 - - - -0.9059 - 2.279 0.506 - 332.1 1 2 0 -0.0013 11 0 0 0 6.46E+07 4.00E+07 - - - 5.0063 0.9999 221125_WJC_METTL3_EV_vs_WT_F02.20342.20342.3 0.00741 Dec-56 K.LSVFANGVVTSIQDR.Y sp|Q9NP61|ARFG3_HUMAN 1 1604.8522 1.04 19365 20342 3 1604.850702 535.958 ADP-ribosylation factor GTPase-activating protein 3 OS=Homo sapiens OX=9606 GN=ARFGAP3 PE=1 SV=1 5.84 3509.4 - 3.49E+06 - - - -0.9465 - 2.494 0.386 - 208.4 1 2 0 -0.0015 15 0 0 0 3.33E+07 3.20E+07 - - - 5.2278 0.9999 221125_WJC_METTL3_EV_vs_WT_F02.20343.20343.2 2.21E-06 13/24 K.GAEEWILTGSYDK[136.11].T sp|Q9GZL7|WDR12_HUMAN 1 1475.7024 1.33 19366 20343 2 1475.70006 738.8585 Ribosome biogenesis protein WDR12 OS=Homo sapiens OX=9606 GN=WDR12 PE=1 SV=2 4.14 3509.4 - 2.87E+06 - - - -1.5687 - 2.68 0.553 - 714.8 1 2 0 -0.0023 13 0 0 0 2.50E+07 1.88E+07 - - - 5.6549 0.9999 221125_WJC_METTL3_EV_vs_WT_F02.20344.20344.2 0.0413 15/24 K.GAEEWILTGSYDK.T sp|Q9GZL7|WDR12_HUMAN 1 1467.6882 1.33 19367 20344 2 1467.688873 734.8514 Ribosome biogenesis protein WDR12 OS=Homo sapiens OX=9606 GN=WDR12 PE=1 SV=2 4.14 3509.5 - 2.62E+06 - - - 0.4756 - 2.732 0.539 - 881.7 1 2 0 0.0007 13 0 0 0 2.50E+07 1.88E+07 - - - 5.6013 0.9985 221125_WJC_METTL3_EV_vs_WT_F02.20345.20345.2 0.013 20-Oct R.NLAGDVC[160.03]AIMR.V "sp|Q8TAQ2|SMRC2_HUMAN,tr|F8VXC8|F8VXC8_HUMAN" 2 1218.5849 0.58 19368 20345 2 1218.581796 610.2997 SWI\SNF complex subunit SMARCC2 OS=Homo sapiens OX=9606 GN=SMARCC2 PE=1 SV=1 5.83 3509.6 - 2.19E+06 - - - -2.5579 - 1.622 0.372 - 301.5 1 2 0 -0.0031 11 0 0 0 1.72E+07 2.94E+07 - - - 3.096 0.9999 221125_WJC_METTL3_EV_vs_WT_F02.20346.20346.3 0.000315 Nov-40 K.HLNSILVLDLR.D sp|Q9H9A6|LRC40_HUMAN 1 1291.7612 1.98 19369 20346 3 1291.760209 431.5944 Leucine-rich repeat-containing protein 40 OS=Homo sapiens OX=9606 GN=LRRC40 PE=1 SV=1 6.74 3509.6 - 1.95E+06 - - - -0.7834 - 2.363 0.395 - 236.2 1 2 0 -0.001 11 0 0 0 1.39E+07 7.06E+06 - - - 5.3865 1 221125_WJC_METTL3_EV_vs_WT_F02.20347.20347.2 1.05E-08 17/44 R.VYTADPYHALAPAASYGVGAVAS.L "sp|O43251|RFOX2_HUMAN,tr|B0QYV1|B0QYV1_HUMAN,tr|A0A0G2JRD1|A0A0G2JRD1_HUMAN,tr|A0A0G2JRA5|A0A0G2JRA5_HUMAN,tr|S4R3K7|S4R3K7_HUMAN" 5 2250.0957 - 19370 20347 2 2250.090026 1126.0551 RNA binding protein fox-1 homolog 2 OS=Homo sapiens OX=9606 GN=RBFOX2 PE=1 SV=3 5.08 3509.8 - 1.42E+06 - - - -2.5208 - 3.165 0.581 - 414.8 1 1 0 -0.0057 23 0 0 0 - - - - - 6.1631 0.9999 221125_WJC_METTL3_EV_vs_WT_F02.20349.20349.2 2.17E-05 16/30 K.LAQMEEAPLFPGESIK[136.11].A "sp|Q13613|MTMR1_HUMAN,tr|E9PPP8|E9PPP8_HUMAN,tr|Q8NEC6|Q8NEC6_HUMAN,tr|H7BZJ1|H7BZJ1_HUMAN,tr|F8WA39|F8WA39_HUMAN,tr|H7C406|H7C406_HUMAN" 6 1766.9004 2.2 19372 20349 2 1766.899653 884.4575 Myotubularin-related protein 1 OS=Homo sapiens OX=9606 GN=MTMR1 PE=1 SV=4 4.25 3510 - 1.01E+06 - - - -0.4358 - 2.635 0.469 - 582.7 1 2 0 -0.0008 16 0 0 0 1.10E+07 4.98E+06 - - - 4.8868 1 221125_WJC_METTL3_EV_vs_WT_F02.20352.20352.2 1.13E-06 17/28 K.LAAVDATVNQVLASR[166.11].Y sp|Q15084|PDIA6_HUMAN 1 1536.8499 1.39 19373 20352 2 1536.848538 769.4322 Protein disulfide-isomerase A6 OS=Homo sapiens OX=9606 GN=PDIA6 PE=1 SV=1 5.84 3510.4 - 8.34E+06 - - - -0.9031 - 3.166 0.53 - 1033.3 1 2 0 -0.0014 15 0 0 0 9.49E+07 6.83E+07 - - - 5.7885 1 221125_WJC_METTL3_EV_vs_WT_F02.20353.20353.2 1.28E-06 20-Oct R.FQIMNEIVYEK.L "sp|O75643|U520_HUMAN,tr|A0A494C1A5|A0A494C1A5_HUMAN" 2 1412.701 1.41 19374 20353 2 1412.699542 707.3578 U5 small nuclear ribonucleoprotein 200 kDa helicase OS=Homo sapiens OX=9606 GN=SNRNP200 PE=1 SV=2 4.53 3510.5 - 8.59E+06 - - - -1.0236 - 2.441 0.6 - 272.5 1 2 0 -0.0014 11 0 0 0 6.70E+07 4.76E+07 - - - 5.8863 0.9996 221125_WJC_METTL3_EV_vs_WT_F02.20354.20354.2 1.94E-05 24-Nov R.LALGSFVEEYNNK[136.11].V "sp|P61962|DCAF7_HUMAN,tr|A0A087WWI6|A0A087WWI6_HUMAN" 2 1490.7497 1.47 19375 20354 2 1490.745925 746.3821 DDB1- and CUL4-associated factor 7 OS=Homo sapiens OX=9606 GN=DCAF7 PE=1 SV=1 4.53 3510.5 - 7.44E+06 - - - -2.5048 - 2.388 0.45 - 360.5 1 2 0 -0.0037 13 0 0 0 1.47E+08 1.00E+08 - - - 4.5976 1 221125_WJC_METTL3_EV_vs_WT_F02.20355.20355.3 5.78E-06 15/56 K.LAAVDATVNQVLASR[166.11].Y sp|Q15084|PDIA6_HUMAN 1 1536.8499 1.3 19376 20355 3 1536.850009 513.2906 Protein disulfide-isomerase A6 OS=Homo sapiens OX=9606 GN=PDIA6 PE=1 SV=1 5.84 3510.5 - 6.22E+06 - - - 0.054 - 2.785 0.467 - 286.3 1 2 0 0.0001 15 0 0 0 4.74E+07 3.65E+07 - - - 6.4192 1 221125_WJC_METTL3_EV_vs_WT_F02.20356.20356.2 2.24E-07 13/26 R.TPTPAGPTIMPLIR.Q "sp|Q96PU8|QKI_HUMAN,tr|H0YG47|H0YG47_HUMAN,tr|H0YGD6|H0YGD6_HUMAN" 3 1463.817 2.58 19377 20356 2 1463.81637 732.9158 Protein quaking OS=Homo sapiens OX=9606 GN=QKI PE=1 SV=1 9.41 3510.6 - 5.91E+06 - - - -0.4447 - 2.71 0.575 - 532.4 1 2 0 -0.0007 14 0 0 0 1.60E+08 6.20E+07 - - - 5.7895 0.9999 221125_WJC_METTL3_EV_vs_WT_F02.20357.20357.2 0.000642 20-Dec R.ALDTMNFDVIK[136.11].G "sp|Q13310|PABP4_HUMAN,sp|Q9H361|PABP3_HUMAN,sp|P11940|PABP1_HUMAN,tr|A0A7I2V5W9|A0A7I2V5W9_HUMAN,tr|A0A7I2V649|A0A7I2V649_HUMAN,tr|B1ANR0|B1ANR0_HUMAN,tr|A0A7I2V4L7|A0A7I2V4L7_HUMAN,tr|B1ANR1|B1ANR1_HUMAN,tr|H0YAR2|H0YAR2_HUMAN,tr|E7ERJ7|E7ERJ7_HUMAN,tr|E5RJB9|E5RJB9_HUMAN,tr|A0A7I2YQ88|A0A7I2YQ88_HUMAN,tr|H0YEQ8|H0YEQ8_HUMAN,tr|E5RH24|E5RH24_HUMAN,tr|H0YBN4|H0YBN4_HUMAN,tr|E5RGH3|E5RGH3_HUMAN,tr|A0A087WTT1|A0A087WTT1_HUMAN,tr|A0A7I2YQ90|A0A7I2YQ90_HUMAN,tr|A0A7I2V4N4|A0A7I2V4N4_HUMAN,tr|E7EQV3|E7EQV3_HUMAN" 20 1273.6468 1.38 19378 20357 2 1273.64563 637.8307 Polyadenylate-binding protein 4 OS=Homo sapiens OX=9606 GN=PABPC4 PE=1 SV=1 4.21 3510.7 - 3.80E+06 - - - -0.8982 - 2.549 0.506 - 389.4 1 2 0 -0.0011 11 0 0 0 7.53E+08 5.44E+08 - - - 5.3092 0.999 221125_WJC_METTL3_EV_vs_WT_F02.20359.20359.3 0.0276 13/36 K.MK[136.11]LDYILGLK[136.11].L "sp|P46781|RS9_HUMAN,tr|C9JM19|C9JM19_HUMAN,tr|B5MCT8|B5MCT8_HUMAN" 3 1208.7174 0.92 19380 20359 3 1208.71702 403.9131 40S ribosomal protein S9 OS=Homo sapiens OX=9606 GN=RPS9 PE=1 SV=3 8.25 3510.9 - 2.41E+06 - - - -0.2871 - 2.169 0.328 - 195.6 1 2 1 -0.0003 10 0 0 0 4.02E+07 4.38E+07 - - - 4.458 1 221125_WJC_METTL3_EV_vs_WT_F02.20361.20361.2 7.48E-05 13/26 K.FYGPEGPYGVFAGR.D sp|O00264|PGRC1_HUMAN 1 1515.7147 1.17 19382 20361 2 1515.710098 758.8646 Membrane-associated progesterone receptor component 1 OS=Homo sapiens OX=9606 GN=PGRMC1 PE=1 SV=3 6 3511.1 - 2.18E+06 - - - -3.0124 - 2.574 0.598 - 559.7 1 2 0 -0.0046 14 0 0 0 1.00E+08 8.55E+07 - - - 5.829 1 221125_WJC_METTL3_EV_vs_WT_F02.20362.20362.2 1.27E-11 18/32 K.LYIGNLNESVTPADLEK.V sp|Q9NZI8|IF2B1_HUMAN 1 1874.9626 1.78 19383 20362 2 1874.966818 938.4886 Insulin-like growth factor 2 mRNA-binding protein 1 OS=Homo sapiens OX=9606 GN=IGF2BP1 PE=1 SV=2 4.14 3511.2 - 1.90E+06 - - - 2.2715 - 3.634 0.661 - 828.6 1 2 0 0.0043 17 0 0 0 3.12E+08 1.75E+08 - - - 7.0942 0.9996 221125_WJC_METTL3_EV_vs_WT_F02.20363.20363.2 1.14E-07 24-Dec R.MAIMVQSPMFDGK.V "sp|P09874|PARP1_HUMAN,tr|A0A7I2V384|A0A7I2V384_HUMAN,tr|A0A7I2V5E9|A0A7I2V5E9_HUMAN,tr|A0A7I2V625|A0A7I2V625_HUMAN,tr|A0A7I2V3E1|A0A7I2V3E1_HUMAN" 5 1453.6768 1.2 19384 20363 2 1453.672799 727.8457 Poly [ADP-ribose] polymerase 1 OS=Homo sapiens OX=9606 GN=PARP1 PE=1 SV=4 5.59 3511.2 - 1.78E+06 - - - -2.7276 - 2.474 0.474 - 559.2 1 2 0 -0.004 13 0 0 0 2.44E+07 2.03E+07 - - - 4.8656 0.9362 221125_WJC_METTL3_EV_vs_WT_F02.20364.20364.2 0.376 13/22 A.TGFIVDPVSNLR.L sp|P15924|DESP_HUMAN 1 1316.7089 999 19385 20364 2 1316.708255 659.3617 Desmoplakin OS=Homo sapiens OX=9606 GN=DSP PE=1 SV=3 5.5 3511.4 - 1.72E+06 - - - -0.4526 - 1.963 0.198 - 469.1 1 1 0 -0.0006 12 0 0 0 1.13E+07 0.00E+00 - - - 2.2779 0.8408 221125_WJC_METTL3_EV_vs_WT_F02.20365.20365.2 0.226 20-Nov K.LDPGLIMEQVK.V sp|Q9Y5L4|TIM13_HUMAN 1 1241.669 -1 19386 20365 2 1241.66346 621.8418 Mitochondrial import inner membrane translocase subunit Tim13 OS=Homo sapiens OX=9606 GN=TIMM13 PE=1 SV=1 4.37 3511.4 - 1.59E+06 - - - -4.4295 - 1.301 0.083 - 192.2 1 2 0 -0.0055 11 0 0 0 0.00E+00 0.00E+00 - - - 0.3641 0.9493 221125_WJC_METTL3_EV_vs_WT_F02.20367.20367.2 0.00815 16-Sep K.ELPPFWEQR.N "sp|Q14527|HLTF_HUMAN,tr|A0A0C4DGA6|A0A0C4DGA6_HUMAN" 2 1200.5928 1.13 19388 20367 2 1200.588446 601.3037 Helicase-like transcription factor OS=Homo sapiens OX=9606 GN=HLTF PE=1 SV=2 4.53 3511.7 - 865413 - - - -3.5916 - 1.511 0.077 - 157.9 1 2 0 -0.0043 9 0 0 0 9.23E+07 8.15E+07 - - - 0.8025 0.9993 221125_WJC_METTL3_EV_vs_WT_F02.20370.20370.2 0.0149 18-Dec K.TLVQILTEPR.N sp|O76031|CLPX_HUMAN 1 1168.6816 1.73 19391 20370 2 1168.680329 585.3481 "ATP-dependent Clp protease ATP-binding subunit clpX-like, mitochondrial OS=Homo sapiens OX=9606 GN=CLPX PE=1 SV=2" 5.66 3512.1 - 671197 - - - -1.0644 - 1.683 0.325 - 357.3 1 2 0 -0.0012 10 0 0 0 1.25E+07 7.20E+06 - - - 2.8942 0.9999 221125_WJC_METTL3_EV_vs_WT_F02.20372.20372.2 0.000212 14/28 R.C[160.03]ALSSPSLAFTPPIK.T sp|Q8NFH5|NUP35_HUMAN 1 1587.8331 1.78 19392 20372 2 1587.83393 794.9238 Nucleoporin NUP35 OS=Homo sapiens OX=9606 GN=NUP35 PE=1 SV=1 8.22 3512.3 - 4.15E+06 - - - 0.5448 - 2.468 0.523 - 509.9 1 2 0 0.0009 15 0 0 0 4.45E+07 2.50E+07 - - - 5.1247 0.9998 221125_WJC_METTL3_EV_vs_WT_F02.20374.20374.2 0.000719 20-Nov R.ALDTMNFDVIK.G "sp|Q13310|PABP4_HUMAN,sp|Q9H361|PABP3_HUMAN,sp|P11940|PABP1_HUMAN,tr|A0A7I2V5W9|A0A7I2V5W9_HUMAN,tr|A0A7I2V649|A0A7I2V649_HUMAN,tr|B1ANR0|B1ANR0_HUMAN,tr|A0A7I2V4L7|A0A7I2V4L7_HUMAN,tr|B1ANR1|B1ANR1_HUMAN,tr|H0YAR2|H0YAR2_HUMAN,tr|E7ERJ7|E7ERJ7_HUMAN,tr|E5RJB9|E5RJB9_HUMAN,tr|A0A7I2YQ88|A0A7I2YQ88_HUMAN,tr|H0YEQ8|H0YEQ8_HUMAN,tr|E5RH24|E5RH24_HUMAN,tr|H0YBN4|H0YBN4_HUMAN,tr|E5RGH3|E5RGH3_HUMAN,tr|A0A087WTT1|A0A087WTT1_HUMAN,tr|A0A7I2YQ90|A0A7I2YQ90_HUMAN,tr|A0A7I2V4N4|A0A7I2V4N4_HUMAN,tr|E7EQV3|E7EQV3_HUMAN" 20 1265.6326 1.38 19393 20374 2 1265.630938 633.8236 Polyadenylate-binding protein 4 OS=Homo sapiens OX=9606 GN=PABPC4 PE=1 SV=1 4.21 3512.5 - 2.30E+07 - - - -1.2926 - 2.407 0.437 - 303.1 1 2 0 -0.0016 11 0 0 0 7.53E+08 5.44E+08 - - - 4.6444 0.9834 221125_WJC_METTL3_EV_vs_WT_F02.20375.20375.2 0.828 26-Jul R.DQVLDNAAVQFC[160.03]AR[166.11].K sp|Q99741|CDC6_HUMAN 1 1615.7652 0.05 19394 20375 2 1615.767374 808.8899 Cell division control protein 6 homolog OS=Homo sapiens OX=9606 GN=CDC6 PE=1 SV=1 4.21 3512.5 - 2.05E+07 - - - 1.3393 - 1.323 0.113 - 114.1 1 2 0 0.0022 14 0 0 0 7.51E+06 1.64E+08 - - - 0.5773 0.9997 221125_WJC_METTL3_EV_vs_WT_F02.20376.20376.3 0.000658 Dec-36 K.MKLDYILGLK.L "sp|P46781|RS9_HUMAN,tr|C9JM19|C9JM19_HUMAN,tr|B5MCT8|B5MCT8_HUMAN" 3 1192.689 0.92 19395 20376 3 1192.687642 398.5703 40S ribosomal protein S9 OS=Homo sapiens OX=9606 GN=RPS9 PE=1 SV=3 8.25 3512.6 - 4.33E+06 - - - -1.1109 - 2.345 0.428 - 165.2 1 2 1 -0.0013 10 0 0 0 4.02E+07 4.38E+07 - - - 5.8005 1 221125_WJC_METTL3_EV_vs_WT_F02.20378.20378.3 0.000644 23/64 R.IGGVQQDTILAEGLHFR.L "sp|Q99623|PHB2_HUMAN,tr|F5H3X6|F5H3X6_HUMAN,tr|A0A7I2V5F0|A0A7I2V5F0_HUMAN,tr|J3KPX7|J3KPX7_HUMAN,tr|F5GY37|F5GY37_HUMAN,tr|A0A3G2KQ93|A0A3G2KQ93_HUMAN,tr|F5H2D2|F5H2D2_HUMAN,tr|F5H0C5|F5H0C5_HUMAN" 8 1852.9795 1.05 19397 20378 3 1852.979908 618.6671 Prohibitin-2 OS=Homo sapiens OX=9606 GN=PHB2 PE=1 SV=2 5.32 3512.7 - 4.04E+06 - - - 0.1954 - 3.55 0.449 - 783.8 1 2 0 0.0004 17 0 0 0 8.87E+07 8.47E+07 - - - 6.7465 1 221125_WJC_METTL3_EV_vs_WT_F02.20380.20380.2 1.09E-13 20/32 K.LYIGNLNESVTPADLEK[136.11].V sp|Q9NZI8|IF2B1_HUMAN 1 1882.9768 1.78 19399 20380 2 1882.974727 942.4957 Insulin-like growth factor 2 mRNA-binding protein 1 OS=Homo sapiens OX=9606 GN=IGF2BP1 PE=1 SV=2 4.14 3512.9 - 2.79E+06 - - - -1.0791 - 3.599 0.691 - 1114.9 1 2 0 -0.002 17 0 0 0 3.12E+08 1.75E+08 - - - 7.2926 0.9974 221125_WJC_METTL3_EV_vs_WT_F02.20381.20381.2 7.64E-06 18-Dec K.MK[136.11]LDYILGLK[136.11].L "sp|P46781|RS9_HUMAN,tr|C9JM19|C9JM19_HUMAN,tr|B5MCT8|B5MCT8_HUMAN" 3 1208.7174 2.71 19400 20381 2 1208.719373 605.366 40S ribosomal protein S9 OS=Homo sapiens OX=9606 GN=RPS9 PE=1 SV=3 8.25 3513 - 2.70E+06 - - - 1.6596 - 2.216 0.481 - 349 1 2 1 0.002 10 0 0 0 5.21E+07 1.92E+07 - - - 4.8141 1 221125_WJC_METTL3_EV_vs_WT_F02.20384.20384.3 6.27E-06 13/44 K.SLNNQFASFIDK.V sp|P04264|K2C1_HUMAN 1 1382.683 999 19403 20384 3 1382.682988 461.9016 "Keratin, type II cytoskeletal 1 OS=Homo sapiens OX=9606 GN=KRT1 PE=1 SV=6" 5.55 3513.2 - 1.96E+06 - - - -0.0304 - 2.338 0.511 - 152.4 1 2 0 0 12 0 0 0 1.22E+07 0.00E+00 - - - 6.5913 0.9999 221125_WJC_METTL3_EV_vs_WT_F02.20386.20386.3 7.66E-05 16/64 K.LYIGNLNESVTPADLEK[136.11].V sp|Q9NZI8|IF2B1_HUMAN 1 1882.9768 1.81 19405 20386 3 1882.976404 628.6662 Insulin-like growth factor 2 mRNA-binding protein 1 OS=Homo sapiens OX=9606 GN=IGF2BP1 PE=1 SV=2 4.14 3513.4 - 1.64E+06 - - - -0.1885 - 2.971 0.412 - 286.5 1 2 0 -0.0004 17 0 0 0 1.21E+08 6.71E+07 - - - 5.8842 0.9994 221125_WJC_METTL3_EV_vs_WT_F02.20387.20387.2 4.19E-06 14/30 R.VLVSGLPPSGSWQDLK.D sp|Q13242|SRSF9_HUMAN 1 1681.9039 1.78 19406 20387 2 1681.900278 841.9592 Serine\arginine-rich splicing factor 9 OS=Homo sapiens OX=9606 GN=SRSF9 PE=1 SV=1 5.81 3513.6 - 1.47E+06 - - - -2.1666 - 2.51 0.348 - 322.9 1 2 0 -0.0036 16 0 0 0 1.33E+07 7.47E+06 - - - 3.8727 1 221125_WJC_METTL3_EV_vs_WT_F02.20389.20389.2 1.06E-10 16/30 R.FMQTFVLAPEGSVANK.F "sp|Q13283|G3BP1_HUMAN,tr|A0A7I2V5M7|A0A7I2V5M7_HUMAN,tr|A0A7P0P2U7|A0A7P0P2U7_HUMAN,tr|A0A7I2YQU8|A0A7I2YQU8_HUMAN,tr|A0A7I2V651|A0A7I2V651_HUMAN,tr|A0A7I2YQN9|A0A7I2YQN9_HUMAN,tr|A0A7I2V2V1|A0A7I2V2V1_HUMAN" 7 1737.876 1.17 19408 20389 2 1737.873492 869.9453 Ras GTPase-activating protein-binding protein 1 OS=Homo sapiens OX=9606 GN=G3BP1 PE=1 SV=1 6 3513.8 - 4.22E+06 - - - -1.4385 - 2.714 0.612 - 673.8 1 2 0 -0.0025 16 0 0 0 3.01E+08 2.58E+08 - - - 6.0151 0.9635 221125_WJC_METTL3_EV_vs_WT_F02.20394.20394.2 0.00397 22-Sep K.NQVALNPQNTVF.D "sp|P0DMV8|HS71A_HUMAN,sp|P0DMV9|HS71B_HUMAN,tr|A0A0G2JIW1|A0A0G2JIW1_HUMAN" 3 1343.6834 - 19412 20394 2 1343.684644 672.849 Heat shock 70 kDa protein 1A OS=Homo sapiens OX=9606 GN=HSPA1A PE=1 SV=1 5.52 3514.3 - 6.49E+06 - - - 0.9526 - 1.415 0.419 - 228.9 1 1 0 0.0013 12 0 0 0 - - - - - 3.0487 0.9998 221125_WJC_METTL3_EV_vs_WT_F02.20395.20395.2 0.00018 18-Sep R.EFSFEAWNAK.L "sp|P78347|GTF2I_HUMAN,tr|A0A494C1K3|A0A494C1K3_HUMAN" 2 1227.556 1.5 19413 20395 2 1227.556313 614.7853 General transcription factor II-I OS=Homo sapiens OX=9606 GN=GTF2I PE=1 SV=2 4.53 3514.4 - 1.36E+07 - - - 0.224 - 1.744 0.51 - 261.4 1 2 0 0.0003 10 0 0 0 5.05E+08 3.38E+08 - - - 4.3602 1 221125_WJC_METTL3_EV_vs_WT_F02.20397.20397.2 2.23E-11 16/26 R.TPTPAGPTIMPLIR[166.11].Q "sp|Q96PU8|QKI_HUMAN,tr|H0YG47|H0YG47_HUMAN,tr|H0YGD6|H0YGD6_HUMAN" 3 1473.8253 2.35 19415 20397 2 1473.829949 737.9199 Protein quaking OS=Homo sapiens OX=9606 GN=QKI PE=1 SV=1 9.41 3514.4 - 7.29E+06 - - - 3.1605 - 3 0.574 - 1016.1 1 2 0 0.0047 14 0 0 0 7.35E+07 3.13E+07 - - - 6.036 0.9997 221125_WJC_METTL3_EV_vs_WT_F02.20398.20398.2 4.93E-05 20-Oct R.MLDMGFEPQIR[166.11].R "sp|O00571|DDX3X_HUMAN,sp|O15523|DDX3Y_HUMAN,sp|Q92841|DDX17_HUMAN,sp|P17844|DDX5_HUMAN,tr|A0A2R8YFR4|A0A2R8YFR4_HUMAN,tr|A0A2R8YCW1|A0A2R8YCW1_HUMAN,tr|A0A7I2V5F5|A0A7I2V5F5_HUMAN,tr|A0A2R8YDH3|A0A2R8YDH3_HUMAN,tr|A0A2R8YDT5|A0A2R8YDT5_HUMAN,tr|A0A2R8Y645|A0A2R8Y645_HUMAN,tr|A0A2R8YF78|A0A2R8YF78_HUMAN,tr|J3KRZ1|J3KRZ1_HUMAN,tr|A0A0D9SFB3|A0A0D9SFB3_HUMAN,tr|A0A2R8YFS5|A0A2R8YFS5_HUMAN,tr|J3QSF1|J3QSF1_HUMAN,tr|A0A7I2V507|A0A7I2V507_HUMAN,tr|A0A5H1ZRQ2|A0A5H1ZRQ2_HUMAN,tr|A0A0D9SF53|A0A0D9SF53_HUMAN,tr|J3KTA4|J3KTA4_HUMAN,tr|A0A0G2JLI4|A0A0G2JLI4_HUMAN,tr|A0A1X7SBZ2|A0A1X7SBZ2_HUMAN,tr|A0A2R8Y5G6|A0A2R8Y5G6_HUMAN,tr|A0A2R8Y7T2|A0A2R8Y7T2_HUMAN,tr|A0A0D9SG12|A0A0D9SG12_HUMAN,tr|A0A7I2V2S0|A0A7I2V2S0_HUMAN,tr|F6S8Q4|F6S8Q4_HUMAN,tr|A0A2U3TZJ9|A0A2U3TZJ9_HUMAN,tr|A0A2R8Y4A4|A0A2R8Y4A4_HUMAN" 28 1345.6398 2 19416 20398 2 1345.637079 673.8272 ATP-dependent RNA helicase DDX3X OS=Homo sapiens OX=9606 GN=DDX3X PE=1 SV=3 4.37 3514.5 - 6.49E+06 - - - -2.0206 - 2.161 0.465 - 396.9 1 2 0 -0.0027 11 0 0 0 9.11E+07 4.55E+07 - - - 4.5592 1 221125_WJC_METTL3_EV_vs_WT_F02.20399.20399.2 3.89E-06 16/30 R.FMQTFVLAPEGSVANK[136.11].F "sp|Q13283|G3BP1_HUMAN,tr|A0A7I2V5M7|A0A7I2V5M7_HUMAN,tr|A0A7P0P2U7|A0A7P0P2U7_HUMAN,tr|A0A7I2YQU8|A0A7I2YQU8_HUMAN,tr|A0A7I2V651|A0A7I2V651_HUMAN,tr|A0A7I2YQN9|A0A7I2YQN9_HUMAN,tr|A0A7I2V2V1|A0A7I2V2V1_HUMAN" 7 1745.8902 1.17 19417 20399 2 1745.889474 873.9524 Ras GTPase-activating protein-binding protein 1 OS=Homo sapiens OX=9606 GN=G3BP1 PE=1 SV=1 6 3514.5 - 5.22E+06 - - - -0.4113 - 2.832 0.636 - 729.8 1 2 0 -0.0007 16 0 0 0 3.01E+08 2.58E+08 - - - 6.2976 0.8934 221125_WJC_METTL3_EV_vs_WT_F02.20400.20400.2 0.000409 22-Nov R.LEALLEAAGIGK[136.11].L "sp|O75179|ANR17_HUMAN,sp|Q8IWZ3|ANKH1_HUMAN,tr|E9PDP5|E9PDP5_HUMAN,tr|H0YM23|H0YM23_HUMAN,tr|A0A1W2PQ15|A0A1W2PQ15_HUMAN" 5 1191.6954 1.43 19418 20400 2 1192.693359 596.855 Ankyrin repeat domain-containing protein 17 OS=Homo sapiens OX=9606 GN=ANKRD17 PE=1 SV=3 4.53 3514.6 - 5.03E+06 - - - 837.3952 - 2.271 0.426 - 376.2 1 2 0 0.9979 12 0 0 0 9.12E+07 6.36E+07 - - - 4.0322 1 221125_WJC_METTL3_EV_vs_WT_F02.20401.20401.3 3.42E-10 17/64 K.LYIGNLNESVTPADLEK.V sp|Q9NZI8|IF2B1_HUMAN 1 1874.9626 1.81 19419 20401 3 1874.961331 625.9948 Insulin-like growth factor 2 mRNA-binding protein 1 OS=Homo sapiens OX=9606 GN=IGF2BP1 PE=1 SV=2 4.14 3514.6 - 4.82E+06 - - - -0.6549 - 3.297 0.618 - 368.6 1 2 0 -0.0012 17 0 0 0 1.22E+08 6.71E+07 - - - 8.4437 0.9999 221125_WJC_METTL3_EV_vs_WT_F02.20402.20402.2 0.000119 22-Dec R.LEALLEAAGIGK.L "sp|O75179|ANR17_HUMAN,sp|Q8IWZ3|ANKH1_HUMAN,tr|E9PDP5|E9PDP5_HUMAN,tr|H0YM23|H0YM23_HUMAN,tr|A0A1W2PQ15|A0A1W2PQ15_HUMAN" 5 1183.6812 1.43 19420 20402 2 1183.681044 592.8479 Ankyrin repeat domain-containing protein 17 OS=Homo sapiens OX=9606 GN=ANKRD17 PE=1 SV=3 4.53 3514.7 - 4.01E+06 - - - -0.1647 - 2.665 0.454 - 520.3 1 2 0 -0.0002 12 0 0 0 9.12E+07 6.36E+07 - - - 4.9733 1 221125_WJC_METTL3_EV_vs_WT_F02.20403.20403.2 0.000351 15/26 K.TQLQQLGVTLSMTR[166.11].T sp|Q7Z3B4|NUP54_HUMAN 1 1584.8533 1.5 19421 20403 2 1584.853888 793.4339 Nucleoporin p54 OS=Homo sapiens OX=9606 GN=NUP54 PE=1 SV=2 9.41 3514.7 - 3.31E+06 - - - 0.3729 - 3.091 0.538 - 753.2 1 2 0 0.0006 14 0 0 0 5.15E+07 3.42E+07 - - - 5.8464 1 221125_WJC_METTL3_EV_vs_WT_F02.20404.20404.3 9.99E-06 18/56 K.LTPLILKPFGNSISR.Y "sp|Q14739|LBR_HUMAN,tr|A0A494C1L1|A0A494C1L1_HUMAN,tr|C9JXK0|C9JXK0_HUMAN" 3 1654.977 1.15 19422 20404 3 1654.977703 552.6663 Delta(14)-sterol reductase LBR OS=Homo sapiens OX=9606 GN=LBR PE=1 SV=2 11 3514.8 - 3.02E+06 - - - 0.4085 - 3.133 0.559 - 369.4 1 2 0 0.0007 15 0 0 0 3.80E+07 3.29E+07 - - - 7.752 1 221125_WJC_METTL3_EV_vs_WT_F02.20406.20406.3 8.23E-07 15/44 K.LSMFVLLPSHSK.D sp|Q96P63|SPB12_HUMAN 1 1357.7428 34.25 19424 20406 3 1357.740664 453.5882 Serpin B12 OS=Homo sapiens OX=9606 GN=SERPINB12 PE=1 SV=1 8.76 3515 - 2.24E+06 - - - -1.568 - 3.025 0.483 - 369.8 1 2 0 -0.0021 12 0 0 0 2.81E+07 8.21E+05 - - - 6.9926 1 221125_WJC_METTL3_EV_vs_WT_F02.20407.20407.3 3.93E-05 23/60 R.FMQTFVLAPEGSVANK.F "sp|Q13283|G3BP1_HUMAN,tr|A0A7I2V5M7|A0A7I2V5M7_HUMAN,tr|A0A7P0P2U7|A0A7P0P2U7_HUMAN,tr|A0A7I2YQU8|A0A7I2YQU8_HUMAN,tr|A0A7I2V651|A0A7I2V651_HUMAN,tr|A0A7I2YQN9|A0A7I2YQN9_HUMAN,tr|A0A7I2V2V1|A0A7I2V2V1_HUMAN" 7 1737.876 1.29 19425 20407 3 1737.873303 580.2993 Ras GTPase-activating protein-binding protein 1 OS=Homo sapiens OX=9606 GN=G3BP1 PE=1 SV=1 6 3515.1 - 1.98E+06 - - - -1.5473 - 3.24 0.485 - 799.3 1 2 0 -0.0027 16 0 0 0 1.19E+08 9.20E+07 - - - 6.9629 0.9122 221125_WJC_METTL3_EV_vs_WT_F02.20409.20409.2 0.27 30-Aug R.AGGSGLAAVVC[160.03]GGGPR[166.11].R tr|H3BQL3|H3BQL3_HUMAN 1 1394.6964 44.42 19427 20409 2 1394.691965 698.3555 UPF0547 protein C16orf87 (Fragment) OS=Homo sapiens OX=9606 GN=C16orf87 PE=1 SV=1 8.29 3515.3 - 1.76E+06 - - - -3.1813 - 1.32 0.095 - 116.2 3 2 0 -0.0044 16 0 0 0 7.24E+08 1.63E+07 - - - 0.2107 0.9987 221125_WJC_METTL3_EV_vs_WT_F02.20415.20415.2 7.95E-05 20-Dec R.NAVWALSNLC[160.03]R[166.11].G "sp|O60684|IMA7_HUMAN,sp|O15131|IMA6_HUMAN,sp|P52294|IMA5_HUMAN,tr|C9JYI4|C9JYI4_HUMAN,tr|Q5TFJ7|Q5TFJ7_HUMAN" 5 1312.6586 0.56 19432 20415 2 1312.663527 657.3366 Importin subunit alpha-7 OS=Homo sapiens OX=9606 GN=KPNA6 PE=1 SV=1 8.25 3516.1 - 795656 - - - 3.7839 - 2.162 0.439 - 632.8 1 2 0 0.005 11 0 0 0 3.75E+06 6.68E+06 - - - 4.3677 0.9996 221125_WJC_METTL3_EV_vs_WT_F02.20416.20416.2 0.0193 16-Jul K.LLQDFFNGR.D "sp|P0DMV8|HS71A_HUMAN,sp|P0DMV9|HS71B_HUMAN,tr|V9GZ37|V9GZ37_HUMAN,tr|A0A0G2JIW1|A0A0G2JIW1_HUMAN" 4 1108.5665 0.14 19433 20416 2 1108.566285 555.2905 Heat shock 70 kDa protein 1A OS=Homo sapiens OX=9606 GN=HSPA1A PE=1 SV=1 5.84 3516.1 - 5.09E+07 - - - -0.2327 - 1.764 0.333 - 149.8 1 2 0 -0.0003 9 0 0 0 1.58E+09 1.11E+10 - - - 3.1425 1 221125_WJC_METTL3_EV_vs_WT_F02.20418.20418.3 4.92E-08 20/68 K.ILGSGISSSSVLHGMVFK[136.11].K sp|P50990|TCPQ_HUMAN 1 1825.9852 0.35 19435 20418 3 1825.984541 609.669 T-complex protein 1 subunit theta OS=Homo sapiens OX=9606 GN=CCT8 PE=1 SV=4 8.76 3516.2 - 5.94E+06 - - - -0.3368 - 3.397 0.64 - 348 1 2 0 -0.0006 18 0 0 0 8.83E+07 2.53E+08 - - - 8.7203 0.9999 221125_WJC_METTL3_EV_vs_WT_F02.20419.20419.2 1.71E-05 13/22 R.QAVQILDELAEK[136.11].L sp|Q99961|SH3G1_HUMAN 1 1363.7438 1.97 19436 20419 2 1363.742473 682.8792 Endophilin-A2 OS=Homo sapiens OX=9606 GN=SH3GL1 PE=1 SV=1 4.14 3516.2 - 4.34E+06 - - - -1.0068 - 2.829 0.431 - 868.3 1 2 0 -0.0014 12 0 0 0 1.86E+08 9.45E+07 - - - 4.9601 0.9191 221125_WJC_METTL3_EV_vs_WT_F02.20420.20420.3 0.00792 Oct-52 K.TQLQQLGVTLSMTR[166.11].T sp|Q7Z3B4|NUP54_HUMAN 1 1584.8533 0.42 19437 20420 3 1585.860806 529.2917 Nucleoporin p54 OS=Homo sapiens OX=9606 GN=NUP54 PE=1 SV=2 9.41 3516.3 - 3.42E+06 - - - 635.7112 - 1.867 0.302 - 86.9 1 2 0 1.0075 14 0 0 0 3.70E+07 8.73E+07 - - - 3.2871 1 221125_WJC_METTL3_EV_vs_WT_F02.20421.20421.3 0.000734 19/44 R.VTMLFLGLHNVR[166.11].Q "sp|P14868|SYDC_HUMAN,tr|H7BZ35|H7BZ35_HUMAN" 2 1408.7888 0.75 19438 20421 3 1408.788748 470.6036 "Aspartate--tRNA ligase, cytoplasmic OS=Homo sapiens OX=9606 GN=DARS1 PE=1 SV=2" 9.73 3516.4 - 3.41E+06 - - - -0.0696 - 3.133 0.498 - 791.6 1 2 0 -0.0001 12 0 0 0 2.47E+07 3.29E+07 - - - 7.2576 0.9999 221125_WJC_METTL3_EV_vs_WT_F02.20422.20422.3 0.000487 Nov-44 K.DILLR[166.11]PELEELR[166.11].N sp|P00387|NB5R3_HUMAN 1 1514.8571 1.38 19439 20422 3 1514.85787 505.9597 NADH-cytochrome b5 reductase 3 OS=Homo sapiens OX=9606 GN=CYB5R3 PE=1 SV=3 4.41 3516.4 - 2.77E+06 - - - 0.4865 - 2.093 0.39 - 126.7 1 2 0 0.0007 12 0 0 0 2.99E+07 2.16E+07 - - - 4.9352 1 221125_WJC_METTL3_EV_vs_WT_F02.20423.20423.3 3.33E-06 17/44 R.VTMLFLGLHNVR.Q "sp|P14868|SYDC_HUMAN,tr|H7BZ35|H7BZ35_HUMAN" 2 1398.7806 0.75 19440 20423 3 1398.781214 467.2675 "Aspartate--tRNA ligase, cytoplasmic OS=Homo sapiens OX=9606 GN=DARS1 PE=1 SV=2" 9.73 3516.5 - 2.46E+06 - - - 0.4561 - 3.115 0.479 - 609.4 1 2 0 0.0006 12 0 0 0 2.47E+07 3.29E+07 - - - 7.0297 0.9044 221125_WJC_METTL3_EV_vs_WT_F02.20425.20425.2 0.0208 12-Aug L.QDFFNGR[166.11].D "sp|P0DMV8|HS71A_HUMAN,sp|P0DMV9|HS71B_HUMAN,tr|V9GZ37|V9GZ37_HUMAN,tr|A0A0G2JIW1|A0A0G2JIW1_HUMAN" 4 892.4067 0.12 19442 20425 2 892.404244 447.2106 Heat shock 70 kDa protein 1A OS=Homo sapiens OX=9606 GN=HSPA1A PE=1 SV=1 5.84 3516.7 - 1.39E+06 - - - -2.7353 - 1.517 0.367 - 177.6 1 1 0 -0.0024 7 0 0 0 3.40E+06 2.79E+07 - - - 3.0713 0.9553 221125_WJC_METTL3_EV_vs_WT_F02.20427.20427.2 0.000716 18-Dec K.SFENIQNWMK[136.11].S "sp|P51153|RAB13_HUMAN,tr|A0A087WWB9|A0A087WWB9_HUMAN" 2 1303.6111 0.38 19444 20427 2 1303.601557 652.8128 Ras-related protein Rab-13 OS=Homo sapiens OX=9606 GN=RAB13 PE=1 SV=1 5.72 3517 - 983535 - - - -7.2874 - 1.597 0.358 - 313.2 1 2 0 -0.0095 10 0 0 0 3.32E+06 8.68E+06 - - - 2.9889 0.9996 221125_WJC_METTL3_EV_vs_WT_F02.20430.20430.3 0.00497 13/60 R.FMQTFVLAPEGSVANK[136.11].F "sp|Q13283|G3BP1_HUMAN,tr|A0A7I2V5M7|A0A7I2V5M7_HUMAN,tr|A0A7P0P2U7|A0A7P0P2U7_HUMAN,tr|A0A7I2YQU8|A0A7I2YQU8_HUMAN,tr|A0A7I2V651|A0A7I2V651_HUMAN,tr|A0A7I2YQN9|A0A7I2YQN9_HUMAN,tr|A0A7I2V2V1|A0A7I2V2V1_HUMAN" 7 1745.8902 1.29 19445 20430 3 1745.886849 582.9707 Ras GTPase-activating protein-binding protein 1 OS=Homo sapiens OX=9606 GN=G3BP1 PE=1 SV=1 6 3517.4 - 7.62E+06 - - - -1.9148 - 2.46 0.316 - 249.8 1 2 0 -0.0033 16 0 0 0 1.18E+08 9.17E+07 - - - 4.3719 0.9998 221125_WJC_METTL3_EV_vs_WT_F02.20431.20431.2 0.000295 18-Oct R.GTLSGWILSK[136.11].A "sp|P27824|CALX_HUMAN,tr|A0A7P0T937|A0A7P0T937_HUMAN,tr|A0A7P0T840|A0A7P0T840_HUMAN,tr|A0A7P0Z4H2|A0A7P0Z4H2_HUMAN,tr|A0A7P0TB65|A0A7P0TB65_HUMAN,tr|A0A7P0TAN9|A0A7P0TAN9_HUMAN,tr|A0A7P0TAE9|A0A7P0TAE9_HUMAN,tr|A0A7P0T8N1|A0A7P0T8N1_HUMAN,tr|A0A7P0T8G1|A0A7P0T8G1_HUMAN,tr|A0A7P0Z4D6|A0A7P0Z4D6_HUMAN,tr|A0A7P0Z484|A0A7P0Z484_HUMAN,tr|A0A7P0TAR9|A0A7P0TAR9_HUMAN,tr|A0A7P0T9L0|A0A7P0T9L0_HUMAN,tr|D6RAQ8|D6RAQ8_HUMAN,tr|D6RAU8|D6RAU8_HUMAN" 15 1068.6059 1.14 19446 20431 2 1068.60549 535.3102 Calnexin OS=Homo sapiens OX=9606 GN=CANX PE=1 SV=2 8.75 3517.4 - 7.40E+06 - - - -0.3799 - 2.064 0.374 - 267.5 1 2 0 -0.0004 10 0 0 0 4.48E+08 3.93E+08 - - - 3.8259 0.9998 221125_WJC_METTL3_EV_vs_WT_F02.20432.20432.2 2.70E-05 18-Oct R.EFSFEAWNAK[136.11].L "sp|P78347|GTF2I_HUMAN,tr|A0A494C1K3|A0A494C1K3_HUMAN" 2 1235.5702 1.49 19447 20432 2 1235.568985 618.7924 General transcription factor II-I OS=Homo sapiens OX=9606 GN=GTF2I PE=1 SV=2 4.53 3517.5 - 3.16E+07 - - - -1.0141 - 1.873 0.5 - 331 1 2 0 -0.0013 10 0 0 0 5.05E+08 3.38E+08 - - - 4.4853 0.9999 221125_WJC_METTL3_EV_vs_WT_F02.20433.20433.2 1.23E-05 18-Nov R.GTLSGWILSK.A "sp|P27824|CALX_HUMAN,tr|A0A7P0T937|A0A7P0T937_HUMAN,tr|A0A7P0T840|A0A7P0T840_HUMAN,tr|A0A7P0Z4H2|A0A7P0Z4H2_HUMAN,tr|A0A7P0TB65|A0A7P0TB65_HUMAN,tr|A0A7P0TAN9|A0A7P0TAN9_HUMAN,tr|A0A7P0TAE9|A0A7P0TAE9_HUMAN,tr|A0A7P0T8N1|A0A7P0T8N1_HUMAN,tr|A0A7P0T8G1|A0A7P0T8G1_HUMAN,tr|A0A7P0Z4D6|A0A7P0Z4D6_HUMAN,tr|A0A7P0Z484|A0A7P0Z484_HUMAN,tr|A0A7P0TAR9|A0A7P0TAR9_HUMAN,tr|A0A7P0T9L0|A0A7P0T9L0_HUMAN,tr|D6RAQ8|D6RAQ8_HUMAN,tr|D6RAU8|D6RAU8_HUMAN" 15 1060.5917 1.14 19448 20433 2 1060.591413 531.3031 Calnexin OS=Homo sapiens OX=9606 GN=CANX PE=1 SV=2 8.75 3517.5 - 6.93E+06 - - - -0.2668 - 2.245 0.455 - 321.5 1 2 0 -0.0003 10 0 0 0 4.48E+08 3.92E+08 - - - 4.6589 1 221125_WJC_METTL3_EV_vs_WT_F02.20437.20437.3 6.02E-05 15/68 K.ILGSGISSSSVLHGMVFK.K sp|P50990|TCPQ_HUMAN 1 1817.971 0.35 19452 20437 3 1817.966923 606.9976 T-complex protein 1 subunit theta OS=Homo sapiens OX=9606 GN=CCT8 PE=1 SV=4 8.76 3517.7 - 3.59E+06 - - - -2.2184 - 2.859 0.547 - 180.5 1 2 0 -0.004 18 0 0 0 8.86E+07 2.54E+08 - - - 7.2532 1 221125_WJC_METTL3_EV_vs_WT_F02.20439.20439.2 9.19E-07 16/24 K.LPFAAAQIGNSFR.N "sp|P41250|GARS_HUMAN,tr|H7C443|H7C443_HUMAN,tr|A0A6Q8PGI6|A0A6Q8PGI6_HUMAN,tr|A0A6Q8PGA8|A0A6Q8PGA8_HUMAN,tr|A0A6Q8PGW4|A0A6Q8PGW4_HUMAN,tr|A0A6Q8PGZ8|A0A6Q8PGZ8_HUMAN,tr|A0A6Q8PH49|A0A6Q8PH49_HUMAN,tr|A0A6Q8PHH9|A0A6Q8PHH9_HUMAN,tr|A0A6Q8PF45|A0A6Q8PF45_HUMAN,tr|A0A6Q8PHI7|A0A6Q8PHI7_HUMAN,tr|A0A6Q8PFZ6|A0A6Q8PFZ6_HUMAN" 11 1390.7357 2.04 19454 20439 2 1390.734392 696.3751 Glycine--tRNA ligase OS=Homo sapiens OX=9606 GN=GARS1 PE=1 SV=3 9.75 3518 - 2.07E+06 - - - -0.965 - 2.881 0.583 - 1156.3 1 2 0 -0.0013 13 0 0 0 5.27E+07 2.59E+07 - - - 6.0624 0.9998 221125_WJC_METTL3_EV_vs_WT_F02.20442.20442.3 0.00308 16/52 R.TPTPAGPTIMPLIR.Q "sp|Q96PU8|QKI_HUMAN,tr|H0YG47|H0YG47_HUMAN,tr|H0YGD6|H0YGD6_HUMAN" 3 1463.817 2.13 19457 20442 3 1463.812885 488.9463 Protein quaking OS=Homo sapiens OX=9606 GN=QKI PE=1 SV=1 9.41 3518.3 - 1.43E+06 - - - -2.8255 - 2.701 0.402 - 303.5 1 2 0 -0.0041 14 0 0 0 1.07E+07 5.01E+06 - - - 5.6613 0.9998 221125_WJC_METTL3_EV_vs_WT_F02.20443.20443.2 6.01E-09 13/28 K.EGAFSNFPISEETIK[136.11].L "sp|Q9NR30|DDX21_HUMAN,sp|Q9BQ39|DDX50_HUMAN" 2 1675.8185 0.91 19458 20443 2 1675.815369 838.9165 Nucleolar RNA helicase 2 OS=Homo sapiens OX=9606 GN=DDX21 PE=1 SV=5 4.25 3518.5 - 1.41E+06 - - - -1.8486 - 2.587 0.512 - 284.2 1 2 0 -0.0031 15 0 0 0 5.46E+07 6.00E+07 - - - 5.1585 0.9777 221125_WJC_METTL3_EV_vs_WT_F02.20444.20444.2 1.33 16-Jul K.NSLLSLSDT.- sp|Q7L2H7|EIF3M_HUMAN 1 948.4764 - 19459 20444 2 948.475314 475.2455 Eukaryotic translation initiation factor 3 subunit M OS=Homo sapiens OX=9606 GN=EIF3M PE=1 SV=1 3.8 3518.6 - 1.33E+06 - - - -1.1355 - 1.173 0.1 - 127.7 1 2 0 -0.0011 9 0 0 0 - - - - - 0.2409 1 221125_WJC_METTL3_EV_vs_WT_F02.20459.20459.2 1.59E-09 19/34 K.ILGSGISSSSVLHGMVFK[136.11].K sp|P50990|TCPQ_HUMAN 1 1825.9852 0.28 19472 20459 2 1825.98524 913.9999 T-complex protein 1 subunit theta OS=Homo sapiens OX=9606 GN=CCT8 PE=1 SV=4 8.76 3520.2 - 1.03E+06 - - - 0.046 - 3.766 0.609 - 1006.8 1 2 0 0.0001 18 0 0 0 6.12E+06 2.21E+07 - - - 6.7991 0.9996 221125_WJC_METTL3_EV_vs_WT_F02.20463.20463.3 0.0501 Nov-48 R.FIITALPTIYHC[160.03]K.D sp|Q9H3N1|TMX1_HUMAN 1 1575.8483 0.46 19474 20463 3 1575.847443 526.2901 Thioredoxin-related transmembrane protein 1 OS=Homo sapiens OX=9606 GN=TMX1 PE=1 SV=1 8.21 3520.7 - 3.34E+06 - - - -0.5572 - 2.138 0.297 - 113.6 1 2 0 -0.0009 13 0 0 0 5.00E+07 1.10E+08 - - - 3.9112 1 221125_WJC_METTL3_EV_vs_WT_F02.20465.20465.3 2.33E-06 22/64 R.IGGVQQDTILAEGLHFR[166.11].L "sp|Q99623|PHB2_HUMAN,tr|F5H3X6|F5H3X6_HUMAN,tr|A0A7I2V5F0|A0A7I2V5F0_HUMAN,tr|J3KPX7|J3KPX7_HUMAN,tr|F5GY37|F5GY37_HUMAN,tr|A0A3G2KQ93|A0A3G2KQ93_HUMAN,tr|F5H2D2|F5H2D2_HUMAN,tr|F5H0C5|F5H0C5_HUMAN" 8 1862.9878 1.04 19476 20465 3 1862.988272 622.0032 Prohibitin-2 OS=Homo sapiens OX=9606 GN=PHB2 PE=1 SV=2 5.32 3520.9 - 2.78E+06 - - - 0.2448 - 4.116 0.564 - 767.6 1 2 0 0.0005 17 0 0 0 8.87E+07 8.52E+07 - - - 8.4023 0.9544 221125_WJC_METTL3_EV_vs_WT_F02.20466.20466.2 0.00143 16-Oct K.KPAFNLSAF.G sp|P49790|NU153_HUMAN 1 993.5284 0.82 19477 20466 2 993.527215 497.7715 Nuclear pore complex protein Nup153 OS=Homo sapiens OX=9606 GN=NUP153 PE=1 SV=2 8.75 3521 - 2.31E+06 - - - -1.1595 - 1.587 0.33 - 273.7 1 1 0 -0.0012 9 0 0 0 3.77E+07 4.57E+07 - - - 2.8142 1 221125_WJC_METTL3_EV_vs_WT_F02.20469.20469.2 3.48E-06 14/22 R.SPALQILLTNTK[136.11].V "sp|Q03426|KIME_HUMAN,tr|F5H8H2|F5H8H2_HUMAN,tr|A0A1B0GWC2|A0A1B0GWC2_HUMAN" 3 1305.7748 1.69 19480 20469 2 1305.776948 653.8947 Mevalonate kinase OS=Homo sapiens OX=9606 GN=MVK PE=1 SV=1 8.47 3521.4 - 1.88E+06 - - - 1.6818 - 2.913 0.535 - 731.1 1 2 0 0.0022 12 0 0 0 4.89E+07 2.89E+07 - - - 5.805 1 221125_WJC_METTL3_EV_vs_WT_F02.20470.20470.2 1.79E-09 15/28 K.YFFGEGYTYGAQLQK[136.11].R sp|Q6P6C2|ALKB5_HUMAN 1 1778.8395 -1 19481 20470 2 1778.84339 890.427 RNA demethylase ALKBH5 OS=Homo sapiens OX=9606 GN=ALKBH5 PE=1 SV=2 6 3521.5 - 1.51E+06 - - - 2.166 - 2.416 0.644 - 514.6 1 2 0 0.0039 15 0 0 0 0.00E+00 0.00E+00 - - - 5.9651 0.9998 221125_WJC_METTL3_EV_vs_WT_F02.20471.20471.2 0.000437 20-Oct K.LSLDVEIATYR.Q "sp|Q7Z794|K2C1B_HUMAN,sp|Q8N1N4|K2C78_HUMAN" 2 1278.682 2.87 19482 20471 2 1278.68218 640.3483 "Keratin, type II cytoskeletal 1b OS=Homo sapiens OX=9606 GN=KRT77 PE=1 SV=3" 4.37 3521.6 - 1.42E+06 - - - 0.1666 - 2.242 0.445 - 139.7 1 2 0 0.0002 11 0 0 0 2.05E+07 7.16E+06 - - - 4.5118 0.9808 221125_WJC_METTL3_EV_vs_WT_F02.20477.20477.3 0.00135 14/48 L.AFDEYGRPFLIIK.D "sp|P48643|TCPE_HUMAN,tr|D6RIZ7|D6RIZ7_HUMAN,tr|E7ENZ3|E7ENZ3_HUMAN,tr|H0Y914|H0Y914_HUMAN" 4 1567.8399 0.53 19486 20477 3 1567.838335 523.6206 T-complex protein 1 subunit epsilon OS=Homo sapiens OX=9606 GN=CCT5 PE=1 SV=1 6.11 3522.4 - 4.91E+06 - - - -0.9759 - 1.98 0.38 - 129.3 1 1 0 -0.0015 13 0 0 0 6.58E+07 1.25E+08 - - - 4.6283 0.9997 221125_WJC_METTL3_EV_vs_WT_F02.20479.20479.2 4.46E-05 22-Nov K.GLTPSQIGVILR[166.11].D "sp|P62277|RS13_HUMAN,tr|J3KMX5|J3KMX5_HUMAN" 2 1262.7586 1.03 19488 20479 2 1262.756924 632.3866 40S ribosomal protein S13 OS=Homo sapiens OX=9606 GN=RPS13 PE=1 SV=2 9.75 3522.5 - 1.01E+07 - - - -1.3209 - 2.358 0.338 - 464.9 1 2 0 -0.0017 12 0 0 0 1.83E+08 1.78E+08 - - - 3.794 0.9997 221125_WJC_METTL3_EV_vs_WT_F02.20480.20480.2 0.0166 18-Nov K.ELQLIPDQLR.H "sp|Q99567|NUP88_HUMAN,tr|J3KMX1|J3KMX1_HUMAN" 2 1223.6874 2.01 19489 20480 2 1223.686116 612.851 Nuclear pore complex protein Nup88 OS=Homo sapiens OX=9606 GN=NUP88 PE=1 SV=2 4.37 3522.6 - 6.80E+06 - - - -1.0387 - 2.24 0.355 - 466.5 1 2 0 -0.0013 10 0 0 0 1.10E+08 5.47E+07 - - - 3.9138 0.9999 221125_WJC_METTL3_EV_vs_WT_F02.20486.20486.3 3.23E-05 15/40 K.ELLNFYAWQHR[166.11].E sp|Q9Y3A4|RRP7A_HUMAN 1 1485.7393 1.01 19495 20486 3 1485.736166 496.2537 Ribosomal RNA-processing protein 7 homolog A OS=Homo sapiens OX=9606 GN=RRP7A PE=1 SV=2 6.85 3523.1 - 2.39E+06 - - - -2.0778 - 2.742 0.452 - 472.8 1 2 0 -0.0031 11 0 0 0 2.00E+07 1.97E+07 - - - 6.444 0.9934 221125_WJC_METTL3_EV_vs_WT_F02.20487.20487.2 9.03E-06 14/26 Y.SSLLSPMSVNAVMK[136.11].V sp|P50991|TCPD_HUMAN 1 1470.7666 0.55 19496 20487 2 1470.766569 736.3906 T-complex protein 1 subunit delta OS=Homo sapiens OX=9606 GN=CCT4 PE=1 SV=4 8.47 3523.2 - 1.48E+06 - - - -0.002 - 2.525 0.496 - 537 1 1 0 0 14 0 0 0 5.43E+06 9.94E+06 - - - 5.0288 0.9995 221125_WJC_METTL3_EV_vs_WT_F02.20489.20489.2 9.31E-07 24-Nov K.FASYLTFSPSEVK.S sp|P54886|P5CS_HUMAN 1 1474.7344 0.82 19498 20489 2 1474.729934 738.3745 Delta-1-pyrroline-5-carboxylate synthase OS=Homo sapiens OX=9606 GN=ALDH18A1 PE=1 SV=2 6 3523.4 - 1.28E+06 - - - -3.0263 - 2.272 0.545 - 343.9 1 2 0 -0.0045 13 0 0 0 1.29E+07 1.57E+07 - - - 5.1712 0.9999 221125_WJC_METTL3_EV_vs_WT_F02.20490.20490.2 7.44E-07 16/30 K.YVLVAGITPTPLGEGK.S "sp|Q6UB35|C1TM_HUMAN,tr|A0A087WVM4|A0A087WVM4_HUMAN,tr|B7ZM99|B7ZM99_HUMAN" 3 1613.9029 0.49 19499 20490 2 1613.901637 807.9587 "Monofunctional C1-tetrahydrofolate synthase, mitochondrial OS=Homo sapiens OX=9606 GN=MTHFD1L PE=1 SV=1" 6 3523.6 - 1.11E+06 - - - -0.7572 - 2.676 0.528 - 752 1 2 0 -0.0012 16 0 0 0 9.77E+06 1.99E+07 - - - 5.3604 0.9908 221125_WJC_METTL3_EV_vs_WT_F02.20491.20491.3 8.53E-05 19/44 M.LAVDAVIAELKK.Q "sp|P10809|CH60_HUMAN,tr|A0A7I2V2X6|A0A7I2V2X6_HUMAN,tr|A0A7I2V599|A0A7I2V599_HUMAN,tr|E7EXB4|E7EXB4_HUMAN,tr|A0A7I2YQ71|A0A7I2YQ71_HUMAN,tr|E7ESH4|E7ESH4_HUMAN,tr|A0A7I2V5M1|A0A7I2V5M1_HUMAN,tr|A0A7I2V5K3|A0A7I2V5K3_HUMAN,tr|A0A7I2V369|A0A7I2V369_HUMAN" 9 1268.7704 1.25 19500 20491 3 1268.766855 423.9307 "60 kDa heat shock protein, mitochondrial OS=Homo sapiens OX=9606 GN=HSPD1 PE=1 SV=2" 6.07 3523.7 - 646256 - - - -2.7846 - 3.102 0.443 - 798.8 1 1 0 -0.0035 12 0 0 0 2.72E+07 2.17E+07 - - - 6.6159 0.9962 221125_WJC_METTL3_EV_vs_WT_F02.20494.20494.2 0.0147 20-Sep K.EKLEATINELV.- sp|P10599|THIO_HUMAN 1 1257.6816 0.79 19501 20494 2 1257.6804 629.8481 Thioredoxin OS=Homo sapiens OX=9606 GN=TXN PE=1 SV=3 4.25 3524.1 - 1.11E+07 - - - -0.9804 - 1.942 0.38 - 299.6 1 2 1 -0.0012 11 0 0 0 2.06E+08 2.62E+08 - - - 3.6428 0.9998 221125_WJC_METTL3_EV_vs_WT_F02.20499.20499.2 0.00011 28-Nov K.EGAFSNFPISEETIK.L "sp|Q9NR30|DDX21_HUMAN,sp|Q9BQ39|DDX50_HUMAN" 2 1667.8043 0.92 19506 20499 2 1667.805541 834.9094 Nucleolar RNA helicase 2 OS=Homo sapiens OX=9606 GN=DDX21 PE=1 SV=5 4.25 3524.3 - 4.97E+06 - - - 0.7639 - 1.783 0.485 - 111.1 1 2 0 0.0013 15 0 0 0 5.46E+07 5.96E+07 - - - 4.0446 1 221125_WJC_METTL3_EV_vs_WT_F02.20500.20500.2 2.46E-09 18/30 K.FMQTFVLAPEGSVPNK.F "sp|Q9UN86|G3BP2_HUMAN,tr|A0A7I2V3E2|A0A7I2V3E2_HUMAN,tr|A0A7I2V647|A0A7I2V647_HUMAN,tr|D6RAC7|D6RAC7_HUMAN,tr|D6RB17|D6RB17_HUMAN,tr|A0A7I2YQS2|A0A7I2YQS2_HUMAN,tr|A0A7I2V3P9|A0A7I2V3P9_HUMAN" 7 1763.8916 2.05 19507 20500 2 1763.888657 882.9531 Ras GTPase-activating protein-binding protein 2 OS=Homo sapiens OX=9606 GN=G3BP2 PE=1 SV=2 6 3524.4 - 3.99E+06 - - - -1.6928 - 3.075 0.603 - 830 1 2 0 -0.003 16 0 0 0 1.03E+08 5.01E+07 - - - 6.2555 1 221125_WJC_METTL3_EV_vs_WT_F02.20502.20502.2 6.04E-10 16/30 K.FMQTFVLAPEGSVPNK[136.11].F "sp|Q9UN86|G3BP2_HUMAN,tr|A0A7I2V3E2|A0A7I2V3E2_HUMAN,tr|A0A7I2V647|A0A7I2V647_HUMAN,tr|D6RAC7|D6RAC7_HUMAN,tr|D6RB17|D6RB17_HUMAN,tr|A0A7I2YQS2|A0A7I2YQS2_HUMAN,tr|A0A7I2V3P9|A0A7I2V3P9_HUMAN" 7 1771.9058 2.05 19509 20502 2 1771.905451 886.9602 Ras GTPase-activating protein-binding protein 2 OS=Homo sapiens OX=9606 GN=G3BP2 PE=1 SV=2 6 3524.6 - 2.80E+06 - - - -0.2212 - 2.979 0.624 - 553.4 1 2 0 -0.0004 16 0 0 0 1.03E+08 5.01E+07 - - - 6.3335 0.9998 221125_WJC_METTL3_EV_vs_WT_F02.20503.20503.2 0.000208 20-Nov K.SNSVEMDWVLK[136.11].H sp|P55795|HNRH2_HUMAN 1 1314.6369 1.28 19510 20503 2 1314.634439 658.3257 Heterogeneous nuclear ribonucleoprotein H2 OS=Homo sapiens OX=9606 GN=HNRNPH2 PE=1 SV=1 4.37 3524.7 - 2.79E+06 - - - -1.9009 - 2.407 0.516 - 562.2 1 2 0 -0.0025 11 0 0 0 8.85E+07 6.93E+07 - - - 5.2276 0.9999 221125_WJC_METTL3_EV_vs_WT_F02.20504.20504.2 0.00011 18-Nov K.DLQMVNISLR[166.11].V "sp|Q99623|PHB2_HUMAN,tr|F5H3X6|F5H3X6_HUMAN,tr|A0A7I2V5F0|A0A7I2V5F0_HUMAN,tr|F5GWA7|F5GWA7_HUMAN,tr|J3KPX7|J3KPX7_HUMAN,tr|F5GY37|F5GY37_HUMAN" 6 1197.6415 1.56 19511 20504 2 1197.641055 599.828 Prohibitin-2 OS=Homo sapiens OX=9606 GN=PHB2 PE=1 SV=2 5.84 3524.8 - 2.74E+06 - - - -0.3824 - 2.212 0.451 - 518.4 1 2 0 -0.0005 10 0 0 0 1.45E+08 9.28E+07 - - - 4.588 0.9983 221125_WJC_METTL3_EV_vs_WT_F02.20507.20507.3 6.97E-06 17/44 M.LAVDAVIAELK[136.11]K[136.11].Q "sp|P10809|CH60_HUMAN,tr|A0A7I2V2X6|A0A7I2V2X6_HUMAN,tr|A0A7I2V599|A0A7I2V599_HUMAN,tr|E7EXB4|E7EXB4_HUMAN,tr|A0A7I2YQ71|A0A7I2YQ71_HUMAN,tr|E7ESH4|E7ESH4_HUMAN,tr|A0A7I2V5M1|A0A7I2V5M1_HUMAN,tr|A0A7I2V5K3|A0A7I2V5K3_HUMAN,tr|A0A7I2V369|A0A7I2V369_HUMAN" 9 1284.7988 1.25 19514 20507 3 1284.796882 429.2735 "60 kDa heat shock protein, mitochondrial OS=Homo sapiens OX=9606 GN=HSPD1 PE=1 SV=2" 6.07 3525.2 - 1.71E+06 - - - -1.4835 - 2.969 0.566 - 507.9 1 1 0 -0.0019 12 0 0 0 2.72E+07 2.17E+07 - - - 7.8662 0.9993 221125_WJC_METTL3_EV_vs_WT_F02.20509.20509.3 0.00259 14/48 K.ADVDAIHEYLLLK[136.11].G sp|Q9UJV9|DDX41_HUMAN 1 1506.8173 0.74 19516 20509 3 1506.816799 503.2797 Probable ATP-dependent RNA helicase DDX41 OS=Homo sapiens OX=9606 GN=DDX41 PE=1 SV=2 4.54 3525.4 - 1.76E+06 - - - -0.3624 - 1.82 0.306 - 102.1 1 2 0 -0.0005 13 0 0 0 1.25E+07 1.69E+07 - - - 3.5751 0.9975 221125_WJC_METTL3_EV_vs_WT_F02.20511.20511.2 0.0468 16-Oct K.LQDPFSLYR[166.11].C sp|P21912|SDHB_HUMAN 1 1147.5901 0.51 19518 20511 2 1147.58612 574.8023 "Succinate dehydrogenase [ubiquinone] iron-sulfur subunit, mitochondrial OS=Homo sapiens OX=9606 GN=SDHB PE=1 SV=3" 5.84 3525.7 - 894173 - - - -3.4934 - 2.166 0.274 - 256.1 1 2 0 -0.004 9 0 0 0 5.95E+06 1.16E+07 - - - 3.2995 0.9997 221125_WJC_METTL3_EV_vs_WT_F02.20514.20514.2 8.02E-06 22-Oct K.GLTPSQIGVILR.D "sp|P62277|RS13_HUMAN,tr|J3KMX5|J3KMX5_HUMAN" 2 1252.7503 1.03 19519 20514 2 1252.749611 627.3824 40S ribosomal protein S13 OS=Homo sapiens OX=9606 GN=RPS13 PE=1 SV=2 9.75 3526.1 - 1.26E+07 - - - -0.5676 - 2.154 0.337 - 382.3 1 2 0 -0.0007 12 0 0 0 1.83E+08 1.78E+08 - - - 3.5488 1 221125_WJC_METTL3_EV_vs_WT_F02.20515.20515.2 8.96E-08 15/30 R.ELDALDANDELTPLGR.L sp|Q08211|DHX9_HUMAN 1 1740.853 1.07 19520 20515 2 1740.851904 871.4338 ATP-dependent RNA helicase A OS=Homo sapiens OX=9606 GN=DHX9 PE=1 SV=4 3.77 3526.1 - 1.26E+07 - - - -0.6342 - 2.994 0.609 - 593.1 1 2 0 -0.0011 16 0 0 0 1.92E+08 1.80E+08 - - - 6.2348 1 221125_WJC_METTL3_EV_vs_WT_F02.20516.20516.2 8.77E-09 16/30 R.ELDALDANDELTPLGR[166.11].L sp|Q08211|DHX9_HUMAN 1 1750.8613 1.07 19521 20516 2 1750.859095 876.4379 ATP-dependent RNA helicase A OS=Homo sapiens OX=9606 GN=DHX9 PE=1 SV=4 3.77 3526.2 - 1.40E+07 - - - -1.2468 - 3.323 0.633 - 819.7 1 2 0 -0.0022 16 0 0 0 1.92E+08 1.80E+08 - - - 6.668 0.9999 221125_WJC_METTL3_EV_vs_WT_F02.20517.20517.2 0.000802 20-Oct K.SNSVEMDWVLK.H sp|P55795|HNRH2_HUMAN 1 1306.6227 1.28 19522 20517 2 1306.622086 654.3186 Heterogeneous nuclear ribonucleoprotein H2 OS=Homo sapiens OX=9606 GN=HNRNPH2 PE=1 SV=1 4.37 3526.2 - 6.68E+06 - - - -0.499 - 2.274 0.505 - 429.7 1 2 0 -0.0007 11 0 0 0 8.85E+07 6.93E+07 - - - 4.9932 0.9996 221125_WJC_METTL3_EV_vs_WT_F02.20518.20518.2 0.00964 18-Nov K.ELQLIPDQLR[166.11].H "sp|Q99567|NUP88_HUMAN,tr|J3KMX1|J3KMX1_HUMAN" 2 1233.6957 2.01 19523 20518 2 1233.694404 617.8551 Nuclear pore complex protein Nup88 OS=Homo sapiens OX=9606 GN=NUP88 PE=1 SV=2 4.37 3526.3 - 3.70E+06 - - - -1.0156 - 2.178 0.321 - 470.3 1 2 0 -0.0013 10 0 0 0 1.10E+08 5.47E+07 - - - 3.5843 1 221125_WJC_METTL3_EV_vs_WT_F02.20519.20519.3 4.89E-10 19/60 R.ELDALDANDELTPLGR.L sp|Q08211|DHX9_HUMAN 1 1740.853 1.17 19524 20519 3 1740.852545 581.2916 ATP-dependent RNA helicase A OS=Homo sapiens OX=9606 GN=DHX9 PE=1 SV=4 3.77 3526.4 - 3.30E+06 - - - -0.266 - 3.258 0.545 - 385.8 1 2 0 -0.0005 16 0 0 0 3.30E+07 2.82E+07 - - - 7.6467 0.9982 221125_WJC_METTL3_EV_vs_WT_F02.20520.20520.2 0.00123 18-Oct K.FAAQELIEVK[136.11].R "sp|Q86U44|MTA70_HUMAN,tr|F5H6D8|F5H6D8_HUMAN,tr|H0YFV6|H0YFV6_HUMAN,tr|B4DTN4|B4DTN4_HUMAN" 4 1154.6427 0.001 19525 20520 2 1154.637621 578.3286 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 4.53 3526.5 - 2.43E+06 - - - -4.3771 - 2.105 0.467 - 239.5 1 2 0 -0.0051 10 0 0 0 0.00E+00 2.87E+07 - - - 4.5663 1 221125_WJC_METTL3_EV_vs_WT_F02.20521.20521.3 4.43E-10 19/60 R.ELDALDANDELTPLGR[166.11].L sp|Q08211|DHX9_HUMAN 1 1750.8613 1.17 19526 20521 3 1750.857733 584.6277 ATP-dependent RNA helicase A OS=Homo sapiens OX=9606 GN=DHX9 PE=1 SV=4 3.77 3526.6 - 2.32E+06 - - - -2.0247 - 3.439 0.591 - 414.4 1 2 0 -0.0035 16 0 0 0 3.28E+07 2.82E+07 - - - 8.2974 0.9893 221125_WJC_METTL3_EV_vs_WT_F02.20523.20523.2 0.00381 22-Dec Q.EILELLNTTTAK[136.11].E "sp|Q86U44|MTA70_HUMAN,tr|H0YFV6|H0YFV6_HUMAN" 2 1352.7642 0.1 19528 20523 2 1352.765358 677.3894 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 4.53 3526.9 - 2.09E+06 - - - 0.8213 - 2.506 0.416 - 435.1 1 1 0 0.0011 12 0 0 0 1.71E+06 1.74E+07 - - - 4.5305 1 221125_WJC_METTL3_EV_vs_WT_F02.20526.20526.2 3.15E-09 14/30 R.FDYAFDDSAPNEMVYR.F "sp|O00139|KIF2A_HUMAN,tr|D6R9M0|D6R9M0_HUMAN,tr|A0A6Q8PFA6|A0A6Q8PFA6_HUMAN,tr|A0A6Q8PGG1|A0A6Q8PGG1_HUMAN,tr|A0A6Q8PGH7|A0A6Q8PGH7_HUMAN,tr|A0A6Q8PG37|A0A6Q8PG37_HUMAN,tr|A0A6Q8PH57|A0A6Q8PH57_HUMAN" 7 1938.8094 1.48 19531 20526 2 1938.809128 970.412 Kinesin-like protein KIF2A OS=Homo sapiens OX=9606 GN=KIF2A PE=1 SV=3 3.84 3527.3 - 1.42E+06 - - - -0.1552 - 3.11 0.753 - 643.4 1 2 0 -0.0003 16 0 0 0 1.16E+07 7.80E+06 - - - 7.3921 0.998 221125_WJC_METTL3_EV_vs_WT_F02.20527.20527.2 3.12E-05 14/22 R.LDIDPSTITWQR[166.11].V "sp|Q6UB35|C1TM_HUMAN,tr|A0A087WVM4|A0A087WVM4_HUMAN,tr|B7ZM99|B7ZM99_HUMAN" 3 1453.7441 0.78 19532 20527 2 1453.751041 727.8793 "Monofunctional C1-tetrahydrofolate synthase, mitochondrial OS=Homo sapiens OX=9606 GN=MTHFD1L PE=1 SV=1" 4.21 3527.4 - 1.35E+06 - - - 4.7993 - 2.838 0.419 - 637.7 1 2 0 0.007 12 0 0 0 1.98E+07 2.52E+07 - - - 4.8781 0.9998 221125_WJC_METTL3_EV_vs_WT_F02.20535.20535.3 4.67E-05 17/44 K.IEEIKDFLLTAR.R "sp|P63173|RL38_HUMAN,tr|J3KT73|J3KT73_HUMAN,tr|J3QL01|J3QL01_HUMAN,tr|J3KSP2|J3KSP2_HUMAN" 4 1446.8082 1.11 19538 20535 3 1446.807208 483.2767 60S ribosomal protein L38 OS=Homo sapiens OX=9606 GN=RPL38 PE=1 SV=2 4.68 3528.2 - 5.10E+06 - - - -0.7064 - 3.095 0.399 - 571.9 1 2 1 -0.001 12 0 0 0 6.77E+08 6.11E+08 - - - 6.1198 0.9994 221125_WJC_METTL3_EV_vs_WT_F02.20536.20536.2 0.000254 22-Nov R.VTAVIPC[160.03]FPYAR[166.11].Q "sp|P60891|PRPS1_HUMAN,sp|P11908|PRPS2_HUMAN,sp|P21108|PRPS3_HUMAN,tr|A0A6Q8PFD1|A0A6Q8PFD1_HUMAN,tr|A0A2R8Y7H4|A0A2R8Y7H4_HUMAN,tr|A6NMS2|A6NMS2_HUMAN,tr|A0A6Q8PHK9|A0A6Q8PHK9_HUMAN,tr|B1ALA9|B1ALA9_HUMAN,tr|A0A6Q8PFD7|A0A6Q8PFD7_HUMAN,tr|B1ALA7|B1ALA7_HUMAN,tr|A0A0B4J207|A0A0B4J207_HUMAN,tr|D3YTJ7|D3YTJ7_HUMAN" 12 1402.7307 2.14 19539 20536 2 1402.734698 702.3726 Ribose-phosphate pyrophosphokinase 1 OS=Homo sapiens OX=9606 GN=PRPS1 PE=1 SV=2 8.19 3528.2 - 4.09E+06 - - - 2.8765 - 2.297 0.466 - 285.1 1 2 0 0.004 12 0 0 0 5.76E+07 2.69E+07 - - - 4.6697 0.999 221125_WJC_METTL3_EV_vs_WT_F02.20537.20537.2 0.00411 26-Dec R.LVTMQIWDTAGQER[166.11].F "sp|P51149|RAB7A_HUMAN,tr|C9J592|C9J592_HUMAN,tr|A0A6Q8PH84|A0A6Q8PH84_HUMAN,tr|C9J8S3|C9J8S3_HUMAN,tr|C9IZZ0|C9IZZ0_HUMAN,tr|A0A6Q8PGE6|A0A6Q8PGE6_HUMAN,tr|A0A6Q8PG52|A0A6Q8PG52_HUMAN" 7 1656.8169 1.17 19540 20537 2 1656.816043 829.4157 Ras-related protein Rab-7a OS=Homo sapiens OX=9606 GN=RAB7A PE=1 SV=1 4.37 3528.3 - 3.81E+06 - - - -0.5239 - 2.696 0.116 - 426.8 1 2 0 -0.0009 14 0 0 0 3.79E+07 3.23E+07 - - - 2.3863 0.9992 221125_WJC_METTL3_EV_vs_WT_F02.20538.20538.2 6.04E-07 13/28 K.TPMENIGLQDSLLSR[166.11].F "sp|P25205|MCM3_HUMAN,tr|J3KQ69|J3KQ69_HUMAN,tr|A0A499FHX9|A0A499FHX9_HUMAN" 3 1682.8537 0.37 19541 20538 2 1682.853992 842.4341 DNA replication licensing factor MCM3 OS=Homo sapiens OX=9606 GN=MCM3 PE=1 SV=3 4.37 3528.3 - 3.74E+06 - - - 0.1789 - 2.399 0.186 - 360.4 1 2 0 0.0003 15 0 0 0 2.44E+07 6.54E+07 - - - 2.5661 0.9997 221125_WJC_METTL3_EV_vs_WT_F02.20539.20539.2 1.22E-05 13/26 R.LVTMQIWDTAGQER.F "sp|P51149|RAB7A_HUMAN,tr|C9J592|C9J592_HUMAN,tr|A0A6Q8PH84|A0A6Q8PH84_HUMAN,tr|C9J8S3|C9J8S3_HUMAN,tr|C9IZZ0|C9IZZ0_HUMAN,tr|A0A6Q8PGE6|A0A6Q8PGE6_HUMAN,tr|A0A6Q8PG52|A0A6Q8PG52_HUMAN" 7 1646.8086 1.11 19542 20539 2 1646.807305 824.4116 Ras-related protein Rab-7a OS=Homo sapiens OX=9606 GN=RAB7A PE=1 SV=1 4.37 3528.4 - 3.65E+06 - - - -0.8113 - 2.661 0.275 - 545.9 1 2 0 -0.0013 14 0 0 0 3.59E+07 3.23E+07 - - - 3.5277 0.9999 221125_WJC_METTL3_EV_vs_WT_F02.20542.20542.3 2.19E-07 22/72 R.IQEIIEQLDVTTSEYEKEK.L "sp|P10809|CH60_HUMAN,tr|A0A7I2V2X6|A0A7I2V2X6_HUMAN,tr|A0A7I2YQK6|A0A7I2YQK6_HUMAN,tr|A0A7I2V599|A0A7I2V599_HUMAN" 4 2294.1529 1.89 19545 20542 3 2294.149031 765.7249 "60 kDa heat shock protein, mitochondrial OS=Homo sapiens OX=9606 GN=HSPD1 PE=1 SV=2" 4.14 3528.6 - 1.89E+06 - - - -1.7035 - 3.323 0.52 - 616 1 2 1 -0.0039 19 0 0 0 1.37E+07 7.23E+06 - - - 7.2867 0.996 221125_WJC_METTL3_EV_vs_WT_F02.20544.20544.2 0.0126 15/22 K.IEEIKDFLLTAR.R "sp|P63173|RL38_HUMAN,tr|J3KT73|J3KT73_HUMAN,tr|J3QL01|J3QL01_HUMAN,tr|J3KSP2|J3KSP2_HUMAN" 4 1446.8082 1.46 19547 20544 2 1446.805087 724.4114 60S ribosomal protein L38 OS=Homo sapiens OX=9606 GN=RPL38 PE=1 SV=2 4.68 3528.9 - 1.51E+06 - - - -2.1724 - 2.797 0.377 - 1058.8 1 2 1 -0.0031 12 0 0 0 1.55E+08 1.06E+08 - - - 4.5308 0.9999 221125_WJC_METTL3_EV_vs_WT_F02.20545.20545.2 0.000268 18-Dec R.LPEIYIQLQR[166.11].E sp|Q9H223|EHD4_HUMAN 1 1281.732 1.88 19548 20545 2 1281.731583 641.8733 EH domain-containing protein 4 OS=Homo sapiens OX=9606 GN=EHD4 PE=1 SV=1 6 3529 - 1.43E+06 - - - -0.3581 - 2.325 0.463 - 674.4 1 2 0 -0.0005 10 0 0 0 3.14E+07 1.67E+07 - - - 4.8157 1 221125_WJC_METTL3_EV_vs_WT_F02.20546.20546.2 1.98E-05 18/28 K.VPGISSIEQGMTGLK.L "sp|Q7Z739|YTHD3_HUMAN,tr|A0A087X0Q1|A0A087X0Q1_HUMAN,tr|A0A024R7W5|A0A024R7W5_HUMAN,tr|A0A087WY31|A0A087WY31_HUMAN" 4 1515.7967 0.77 19549 20546 2 1515.794514 758.9056 YTH domain-containing family protein 3 OS=Homo sapiens OX=9606 GN=YTHDF3 PE=1 SV=1 5.97 3529.1 - 1.37E+06 - - - -1.429 - 2.917 0.591 - 1095 1 2 0 -0.0022 15 0 0 0 2.09E+07 2.73E+07 - - - 6.0375 0.9995 221125_WJC_METTL3_EV_vs_WT_F02.20548.20548.3 0.00509 Nov-40 K.ELLNFYAWQHR.E sp|Q9Y3A4|RRP7A_HUMAN 1 1475.731 1.01 19551 20548 3 1475.727895 492.9176 Ribosomal RNA-processing protein 7 homolog A OS=Homo sapiens OX=9606 GN=RRP7A PE=1 SV=2 6.85 3529.4 - 817707 - - - -2.0925 - 2.222 0.312 - 214 1 2 0 -0.0031 11 0 0 0 2.00E+07 1.97E+07 - - - 4.2858 0.9999 221125_WJC_METTL3_EV_vs_WT_F02.20549.20549.3 1.94E-05 Dec-32 K.DGAMFFHWR[166.11].R "sp|Q9NPF5|DMAP1_HUMAN,tr|Q5TG39|Q5TG39_HUMAN,tr|Q5TG38|Q5TG38_HUMAN,tr|Q5TG40|Q5TG40_HUMAN,tr|Q5TG36|Q5TG36_HUMAN,tr|Q5TG37|Q5TG37_HUMAN" 6 1175.521 1.01 19552 20549 3 1175.519559 392.8476 DNA methyltransferase 1-associated protein 1 OS=Homo sapiens OX=9606 GN=DMAP1 PE=1 SV=1 6.74 3529.5 - 610029 - - - -1.2292 - 2.266 0.359 - 336 1 2 0 -0.0014 9 0 0 0 3.34E+06 3.32E+06 - - - 5.0074 0.9999 221125_WJC_METTL3_EV_vs_WT_F02.20553.20553.2 0.0177 17/30 K.IFVGGLSANTVVEDVK.Q "sp|Q96DH6|MSI2H_HUMAN,tr|B4DHE8|B4DHE8_HUMAN,tr|A0A6Q8PF05|A0A6Q8PF05_HUMAN,tr|B4DM51|B4DM51_HUMAN,tr|J3KTC1|J3KTC1_HUMAN" 5 1646.8879 1.43 19554 20553 2 1646.888743 824.4512 RNA-binding protein Musashi homolog 2 OS=Homo sapiens OX=9606 GN=MSI2 PE=1 SV=1 4.37 3530 - 1.48E+07 - - - 0.4894 - 3.043 0.522 - 784.5 1 2 0 0.0008 16 0 0 0 4.82E+08 3.37E+08 - - - 5.6322 1 221125_WJC_METTL3_EV_vs_WT_F02.20554.20554.2 7.44E-08 16/30 K.IFVGGLSANTVVEDVK[136.11].Q "sp|Q96DH6|MSI2H_HUMAN,tr|B4DHE8|B4DHE8_HUMAN,tr|A0A6Q8PF05|A0A6Q8PF05_HUMAN,tr|B4DM51|B4DM51_HUMAN,tr|J3KTC1|J3KTC1_HUMAN" 5 1654.9021 1.43 19555 20554 2 1654.902853 828.4583 RNA-binding protein Musashi homolog 2 OS=Homo sapiens OX=9606 GN=MSI2 PE=1 SV=1 4.37 3530 - 1.22E+07 - - - 0.4327 - 3.176 0.653 - 629.9 1 2 0 0.0007 16 0 0 0 4.82E+08 3.36E+08 - - - 6.705 0.9997 221125_WJC_METTL3_EV_vs_WT_F02.20555.20555.2 0.00134 22-Dec R.VQVALEELQDLK.G "sp|Q14204|DYHC1_HUMAN,tr|A0A7P0T8N2|A0A7P0T8N2_HUMAN,tr|A0A7P0T9C4|A0A7P0T9C4_HUMAN,tr|A0A7P0TBJ7|A0A7P0TBJ7_HUMAN,tr|A0A804HHY6|A0A804HHY6_HUMAN,tr|A0A7P0T9K2|A0A7P0T9K2_HUMAN,tr|A0A7P0TB64|A0A7P0TB64_HUMAN,tr|A0A2R8Y706|A0A2R8Y706_HUMAN,tr|A0A7P0T916|A0A7P0T916_HUMAN,tr|A0A7P0TB75|A0A7P0TB75_HUMAN,tr|A0A7P0T8W5|A0A7P0T8W5_HUMAN,tr|A0A7P0T9S3|A0A7P0T9S3_HUMAN,tr|A0A7P0TAF3|A0A7P0TAF3_HUMAN,tr|A0A7P0T9F1|A0A7P0T9F1_HUMAN,tr|A0A7P0TAW9|A0A7P0TAW9_HUMAN,tr|A0A2R8YGC7|A0A2R8YGC7_HUMAN,tr|A0A7P0TA13|A0A7P0TA13_HUMAN,tr|A0A7P0T934|A0A7P0T934_HUMAN,tr|A0A7P0TAV5|A0A7P0TAV5_HUMAN,tr|A0A7P0T9Y3|A0A7P0T9Y3_HUMAN,tr|A0A7P0T7V5|A0A7P0T7V5_HUMAN,tr|A0A7P0T9R4|A0A7P0T9R4_HUMAN,tr|A0A2R8Y5T0|A0A2R8Y5T0_HUMAN,tr|A0A7P0T990|A0A7P0T990_HUMAN,tr|A0A7P0T942|A0A7P0T942_HUMAN,tr|A0A2R8YFZ7|A0A2R8YFZ7_HUMAN,tr|A0A7P0T825|A0A7P0T825_HUMAN,tr|A0A2R8Y6H2|A0A2R8Y6H2_HUMAN,tr|A0A7P0TAM4|A0A7P0TAM4_HUMAN" 29 1383.7609 1.05 19556 20555 2 1383.763611 692.8877 Cytoplasmic dynein 1 heavy chain 1 OS=Homo sapiens OX=9606 GN=DYNC1H1 PE=1 SV=5 4.14 3530.1 - 4.79E+06 - - - 1.9259 - 2.469 0.433 - 467.9 1 2 0 0.0027 12 0 0 0 3.50E+07 3.33E+07 - - - 4.6164 1 221125_WJC_METTL3_EV_vs_WT_F02.20556.20556.3 2.83E-05 15/60 K.EPPLSLTIHLTSPVVR.E "sp|Q12906|ILF3_HUMAN,tr|K7EQR9|K7EQR9_HUMAN,tr|K7EKY0|K7EKY0_HUMAN,tr|K7EPG3|K7EPG3_HUMAN,tr|K7EKJ9|K7EKJ9_HUMAN" 5 1758.004 1.27 19557 20556 3 1758.005995 587.0086 Interleukin enhancer-binding factor 3 OS=Homo sapiens OX=9606 GN=ILF3 PE=1 SV=3 6.85 3530.1 - 4.05E+06 - - - 1.1519 - 2.733 0.52 - 330.8 1 2 0 0.002 16 0 0 0 5.42E+07 4.28E+07 - - - 6.9166 0.9996 221125_WJC_METTL3_EV_vs_WT_F02.20557.20557.2 0.00363 22-Oct R.VQVALEELQDLK[136.11].G "sp|Q14204|DYHC1_HUMAN,tr|A0A7P0T8N2|A0A7P0T8N2_HUMAN,tr|A0A7P0T9C4|A0A7P0T9C4_HUMAN,tr|A0A7P0TBJ7|A0A7P0TBJ7_HUMAN,tr|A0A804HHY6|A0A804HHY6_HUMAN,tr|A0A7P0T9K2|A0A7P0T9K2_HUMAN,tr|A0A7P0TB64|A0A7P0TB64_HUMAN,tr|A0A2R8Y706|A0A2R8Y706_HUMAN,tr|A0A7P0T916|A0A7P0T916_HUMAN,tr|A0A7P0TB75|A0A7P0TB75_HUMAN,tr|A0A7P0T8W5|A0A7P0T8W5_HUMAN,tr|A0A7P0T9S3|A0A7P0T9S3_HUMAN,tr|A0A7P0TAF3|A0A7P0TAF3_HUMAN,tr|A0A7P0T9F1|A0A7P0T9F1_HUMAN,tr|A0A7P0TAW9|A0A7P0TAW9_HUMAN,tr|A0A2R8YGC7|A0A2R8YGC7_HUMAN,tr|A0A7P0TA13|A0A7P0TA13_HUMAN,tr|A0A7P0T934|A0A7P0T934_HUMAN,tr|A0A7P0TAV5|A0A7P0TAV5_HUMAN,tr|A0A7P0T9Y3|A0A7P0T9Y3_HUMAN,tr|A0A7P0T7V5|A0A7P0T7V5_HUMAN,tr|A0A7P0T9R4|A0A7P0T9R4_HUMAN,tr|A0A2R8Y5T0|A0A2R8Y5T0_HUMAN,tr|A0A7P0T990|A0A7P0T990_HUMAN,tr|A0A7P0T942|A0A7P0T942_HUMAN,tr|A0A2R8YFZ7|A0A2R8YFZ7_HUMAN,tr|A0A7P0T825|A0A7P0T825_HUMAN,tr|A0A2R8Y6H2|A0A2R8Y6H2_HUMAN,tr|A0A7P0TAM4|A0A7P0TAM4_HUMAN" 29 1391.7751 1.05 19558 20557 2 1391.778228 696.8948 Cytoplasmic dynein 1 heavy chain 1 OS=Homo sapiens OX=9606 GN=DYNC1H1 PE=1 SV=5 4.14 3530.2 - 4.03E+06 - - - 2.2144 - 2.302 0.423 - 291.1 1 2 0 0.0031 12 0 0 0 3.50E+07 3.33E+07 - - - 4.3581 0.9736 221125_WJC_METTL3_EV_vs_WT_F02.20559.20559.3 2.71 Sep-52 R.LVTMQIWDTAGQER[166.11].F "sp|P51149|RAB7A_HUMAN,tr|C9J592|C9J592_HUMAN,tr|A0A6Q8PH84|A0A6Q8PH84_HUMAN,tr|C9J8S3|C9J8S3_HUMAN,tr|C9IZZ0|C9IZZ0_HUMAN,tr|A0A6Q8PGE6|A0A6Q8PGE6_HUMAN,tr|A0A6Q8PG52|A0A6Q8PG52_HUMAN" 7 1656.8169 1.33 19560 20559 3 1656.81615 553.2796 Ras-related protein Rab-7a OS=Homo sapiens OX=9606 GN=RAB7A PE=1 SV=1 4.37 3530.3 - 3.15E+06 - - - -0.4593 - 1.847 0.095 - 114 1 2 0 -0.0008 14 0 0 0 3.00E+07 2.25E+07 - - - 1.2295 0.9999 221125_WJC_METTL3_EV_vs_WT_F02.20560.20560.2 4.37E-06 24-Nov K.LFPDTPLALDANK[136.11].K sp|Q12906|ILF3_HUMAN 1 1421.7646 1.23 19561 20560 2 1421.764901 711.8896 Interleukin enhancer-binding factor 3 OS=Homo sapiens OX=9606 GN=ILF3 PE=1 SV=3 4.21 3530.4 - 1.64E+06 - - - 0.2251 - 2.05 0.499 - 381 1 2 0 0.0003 13 0 0 0 2.44E+07 1.98E+07 - - - 4.5689 0.9983 221125_WJC_METTL3_EV_vs_WT_F02.20561.20561.3 2.38E-07 16/60 H.TVPIYEGYALPHAILR.L "sp|P63261|ACTG_HUMAN,sp|P60709|ACTB_HUMAN,tr|A0A804GS07|A0A804GS07_HUMAN,tr|I3L3I0|I3L3I0_HUMAN,tr|E7EVS6|E7EVS6_HUMAN,tr|A0A6Q8PFE4|A0A6Q8PFE4_HUMAN,tr|I3L1U9|I3L1U9_HUMAN,tr|A0A2R8YEA7|A0A2R8YEA7_HUMAN,tr|A0A2R8Y793|A0A2R8Y793_HUMAN,tr|I3L4N8|I3L4N8_HUMAN" 10 1811.9934 1.17 19562 20561 3 1811.995047 605.0051 "Actin, cytoplasmic 2 OS=Homo sapiens OX=9606 GN=ACTG1 PE=1 SV=1" 6.41 3530.5 - 1.21E+06 - - - 0.9056 - 2.862 0.557 - 310.9 1 1 0 0.0016 16 0 0 0 7.02E+06 6.01E+06 - - - 7.4476 0.9973 221125_WJC_METTL3_EV_vs_WT_F02.20563.20563.3 0.000218 Nov-48 R.NLLESYHVPELIK[136.11].D "sp|P42704|LPPRC_HUMAN,tr|A0A804HI14|A0A804HI14_HUMAN,tr|A0A804HL40|A0A804HL40_HUMAN,tr|A0A804HKJ0|A0A804HKJ0_HUMAN,tr|A0A804HKR3|A0A804HKR3_HUMAN,tr|A0A804HIN4|A0A804HIN4_HUMAN,tr|A0A804HLG8|A0A804HLG8_HUMAN,tr|A0A804HIV5|A0A804HIV5_HUMAN,tr|A0A804HHY9|A0A804HHY9_HUMAN,tr|A0A804HJH8|A0A804HJH8_HUMAN,tr|B8ZZ38|B8ZZ38_HUMAN,tr|A0A804HI40|A0A804HI40_HUMAN,tr|A0A804HJZ1|A0A804HJZ1_HUMAN,tr|C9JCA9|C9JCA9_HUMAN,tr|A0A804HIQ7|A0A804HIQ7_HUMAN,tr|A0A804HK30|A0A804HK30_HUMAN,tr|A0A804HKI2|A0A804HKI2_HUMAN,tr|A0A804HJI0|A0A804HJI0_HUMAN,tr|A0A804HIG4|A0A804HIG4_HUMAN,tr|A0A804HK02|A0A804HK02_HUMAN" 20 1561.8595 0.68 19564 20563 3 1561.861842 521.6271 "Leucine-rich PPR motif-containing protein, mitochondrial OS=Homo sapiens OX=9606 GN=LRPPRC PE=1 SV=3" 5.4 3530.7 - 1.18E+06 - - - 1.4713 - 2.123 0.204 - 145 1 2 0 0.0023 13 0 0 0 8.41E+06 1.24E+07 - - - 2.8549 0.9996 221125_WJC_METTL3_EV_vs_WT_F02.20564.20564.2 2.33E-06 30-Dec K.LLPEYPGVLSDVQEEK.G sp|P00374|DYR_HUMAN 1 1814.9302 1.62 19565 20564 2 1814.935129 908.4724 Dihydrofolate reductase OS=Homo sapiens OX=9606 GN=DHFR PE=1 SV=2 4 3530.8 - 649621 - - - 2.718 - 2.115 0.541 - 202.6 1 2 0 0.0049 16 0 0 0 6.18E+06 3.82E+06 - - - 4.8769 0.9998 221125_WJC_METTL3_EV_vs_WT_F02.20565.20565.2 0.000134 24-Oct R.ASFITANGVSLLK.D "sp|Q9H3U1|UN45A_HUMAN,tr|A0A1W2PNX8|A0A1W2PNX8_HUMAN" 2 1319.7449 0.96 19566 20565 2 1319.744204 660.8797 Protein unc-45 homolog A OS=Homo sapiens OX=9606 GN=UNC45A PE=1 SV=1 8.8 3530.9 - 632492 - - - -0.5289 - 1.868 0.441 - 143.7 1 2 0 -0.0007 13 0 0 0 5.40E+06 5.64E+06 - - - 3.9017 0.9975 221125_WJC_METTL3_EV_vs_WT_F02.20567.20567.2 0.00037 30-Nov K.LLPEYPGVLSDVQEEK[136.11].G sp|P00374|DYR_HUMAN 1 1822.9444 1.62 19568 20567 2 1822.937698 912.4795 Dihydrofolate reductase OS=Homo sapiens OX=9606 GN=DHFR PE=1 SV=2 4 3531.2 - 468673 - - - -3.6743 - 1.908 0.381 - 200.1 1 2 0 -0.0067 16 0 0 0 6.18E+06 3.82E+06 - - - 3.4413 0.9999 221125_WJC_METTL3_EV_vs_WT_F02.20572.20572.2 2.30E-09 24-Dec R.GDGPIC[160.03]LVLAPTR.E "sp|Q92841|DDX17_HUMAN,sp|P17844|DDX5_HUMAN,tr|A0A7I2V5F5|A0A7I2V5F5_HUMAN,tr|J3KRZ1|J3KRZ1_HUMAN,tr|A0A7I2V507|A0A7I2V507_HUMAN,tr|A0A5H1ZRQ2|A0A5H1ZRQ2_HUMAN,tr|J3KTA4|J3KTA4_HUMAN,tr|A0A0G2JLI4|A0A0G2JLI4_HUMAN,tr|A0A1X7SBZ2|A0A1X7SBZ2_HUMAN,tr|A0A7I2V2S0|A0A7I2V2S0_HUMAN,tr|J3QRQ7|J3QRQ7_HUMAN" 11 1367.7231 1.42 19571 20572 2 1367.723445 684.8688 Probable ATP-dependent RNA helicase DDX17 OS=Homo sapiens OX=9606 GN=DDX17 PE=1 SV=2 5.83 3531.9 - 7.03E+06 - - - 0.2369 - 2.425 0.513 - 527.3 1 2 0 0.0003 13 0 0 0 2.83E+08 1.99E+08 - - - 5.1034 0.9992 221125_WJC_METTL3_EV_vs_WT_F02.20573.20573.2 0.845 18-Oct R.YLNWIGVPTK.V "sp|Q16875|F263_HUMAN,sp|O60825|F262_HUMAN,tr|A0A1W2PR17|A0A1W2PR17_HUMAN,tr|Q5W015|Q5W015_HUMAN,tr|A0A1W2PNV9|A0A1W2PNV9_HUMAN,tr|F2Z2I2|F2Z2I2_HUMAN,tr|F6RAZ1|F6RAZ1_HUMAN,tr|F6XNB3|F6XNB3_HUMAN,tr|Q5VX20|Q5VX20_HUMAN" 9 1189.6495 10.54 19572 20573 2 1189.64824 595.832 "6-phosphofructo-2-kinase\fructose-2,6-bisphosphatase 3 OS=Homo sapiens OX=9606 GN=PFKFB3 PE=1 SV=1" 8.59 3531.9 - 7.74E+06 - - - -1.097 - 1.845 0.277 - 311.6 1 2 0 -0.0013 10 0 0 0 8.52E+07 8.08E+06 - - - 2.7961 1 221125_WJC_METTL3_EV_vs_WT_F02.20574.20574.2 5.55E-07 15/24 R.GDGPIC[160.03]LVLAPTR[166.11].E "sp|Q92841|DDX17_HUMAN,sp|P17844|DDX5_HUMAN,tr|A0A7I2V5F5|A0A7I2V5F5_HUMAN,tr|J3KRZ1|J3KRZ1_HUMAN,tr|A0A7I2V507|A0A7I2V507_HUMAN,tr|A0A5H1ZRQ2|A0A5H1ZRQ2_HUMAN,tr|J3KTA4|J3KTA4_HUMAN,tr|A0A0G2JLI4|A0A0G2JLI4_HUMAN,tr|A0A1X7SBZ2|A0A1X7SBZ2_HUMAN,tr|A0A7I2V2S0|A0A7I2V2S0_HUMAN,tr|J3QRQ7|J3QRQ7_HUMAN" 11 1377.7314 1.43 19573 20574 2 1377.732656 689.873 Probable ATP-dependent RNA helicase DDX17 OS=Homo sapiens OX=9606 GN=DDX17 PE=1 SV=2 5.83 3532 - 5.37E+06 - - - 0.9182 - 2.692 0.588 - 888.1 1 2 0 0.0013 13 0 0 0 2.83E+08 1.99E+08 - - - 5.9252 0.9983 221125_WJC_METTL3_EV_vs_WT_F02.20575.20575.3 3.94E-05 Nov-60 K.IFVGGLSANTVVEDVK.Q "sp|Q96DH6|MSI2H_HUMAN,tr|B4DHE8|B4DHE8_HUMAN,tr|A0A6Q8PF05|A0A6Q8PF05_HUMAN,tr|B4DM51|B4DM51_HUMAN,tr|J3KTC1|J3KTC1_HUMAN" 5 1646.8879 1.48 19574 20575 3 1646.889141 549.9699 RNA-binding protein Musashi homolog 2 OS=Homo sapiens OX=9606 GN=MSI2 PE=1 SV=1 4.37 3532 - 4.64E+06 - - - 0.7311 - 1.877 0.249 - 151.3 1 2 0 0.0012 16 0 0 0 4.72E+07 3.19E+07 - - - 2.9314 0.9999 221125_WJC_METTL3_EV_vs_WT_F02.20576.20576.3 9.19E-06 Nov-60 K.IFVGGLSANTVVEDVK[136.11].Q "sp|Q96DH6|MSI2H_HUMAN,tr|B4DHE8|B4DHE8_HUMAN,tr|A0A6Q8PF05|A0A6Q8PF05_HUMAN,tr|B4DM51|B4DM51_HUMAN,tr|J3KTC1|J3KTC1_HUMAN" 5 1654.9021 1.52 19575 20576 3 1654.902469 552.6413 RNA-binding protein Musashi homolog 2 OS=Homo sapiens OX=9606 GN=MSI2 PE=1 SV=1 4.37 3532 - 3.62E+06 - - - 0.2006 - 1.997 0.488 - 126.3 1 2 0 0.0003 16 0 0 0 4.72E+07 3.11E+07 - - - 5.7553 0.9669 221125_WJC_METTL3_EV_vs_WT_F02.20577.20577.2 0.0013 24-Oct R.QAQIEVVPSASAL.L sp|P30050|RL12_HUMAN 1 1311.7034 - 19576 20577 2 1311.705676 656.859 60S ribosomal protein L12 OS=Homo sapiens OX=9606 GN=RPL12 PE=1 SV=1 4 3532.1 - 3.20E+06 - - - 1.7115 - 2.005 0.376 - 274.9 1 1 0 0.0022 13 0 0 0 - - - - - 3.6028 0.9998 221125_WJC_METTL3_EV_vs_WT_F02.20578.20578.2 7.38E-05 24-Dec K.LFPDTPLALDANK.K sp|Q12906|ILF3_HUMAN 1 1413.7504 1.23 19577 20578 2 1413.752115 707.8825 Interleukin enhancer-binding factor 3 OS=Homo sapiens OX=9606 GN=ILF3 PE=1 SV=3 4.21 3532.1 - 3.07E+06 - - - 1.2265 - 2.083 0.5 - 479.3 1 2 0 0.0017 13 0 0 0 2.44E+07 1.98E+07 - - - 4.6168 0.9999 221125_WJC_METTL3_EV_vs_WT_F02.20579.20579.2 2.10E-06 15/24 K.QLAAAFQEEFTVR.E sp|P51116|FXR2_HUMAN 1 1508.7623 2.51 19578 20579 2 1508.762929 755.3884 Fragile X mental retardation syndrome-related protein 2 OS=Homo sapiens OX=9606 GN=FXR2 PE=1 SV=2 4.53 3532.2 - 2.91E+06 - - - 0.3884 - 2.804 0.518 - 1146.5 1 2 0 0.0006 13 0 0 0 2.34E+07 9.31E+06 - - - 5.513 0.9916 221125_WJC_METTL3_EV_vs_WT_F02.20580.20580.3 0.0549 Oct-60 K.FMQTFVLAPEGSVPNK.F "sp|Q9UN86|G3BP2_HUMAN,tr|A0A7I2V3E2|A0A7I2V3E2_HUMAN,tr|A0A7I2V647|A0A7I2V647_HUMAN,tr|D6RAC7|D6RAC7_HUMAN,tr|D6RB17|D6RB17_HUMAN,tr|A0A7I2YQS2|A0A7I2YQS2_HUMAN,tr|A0A7I2V3P9|A0A7I2V3P9_HUMAN" 7 1763.8916 2.36 19579 20580 3 1763.893894 588.9712 Ras GTPase-activating protein-binding protein 2 OS=Homo sapiens OX=9606 GN=G3BP2 PE=1 SV=2 6 3532.2 - 7.49E+06 - - - 1.2762 - 1.535 0.217 - 90.7 1 2 0 0.0023 16 0 0 0 4.67E+07 1.98E+07 - - - 2.0583 0.9997 221125_WJC_METTL3_EV_vs_WT_F02.20581.20581.2 0.0601 20-Nov K.LVFLGLDNAGK.T "sp|Q9NR31|SAR1A_HUMAN,sp|Q9Y6B6|SAR1B_HUMAN,tr|D6RAA2|D6RAA2_HUMAN,tr|D6RD69|D6RD69_HUMAN,tr|X1WI22|X1WI22_HUMAN,tr|Q5SQT8|Q5SQT8_HUMAN,tr|D6RDB2|D6RDB2_HUMAN" 7 1145.6445 1.15 19580 20581 2 1145.64579 573.8295 GTP-binding protein SAR1a OS=Homo sapiens OX=9606 GN=SAR1A PE=1 SV=1 5.84 3532.3 - 2.65E+06 - - - 1.1618 - 2.058 0.417 - 379.5 1 2 0 0.0013 11 0 0 0 6.34E+08 5.53E+08 - - - 4.073 0.9999 221125_WJC_METTL3_EV_vs_WT_F02.20584.20584.3 7.15E-06 14/48 K.MLNIHPSLLPSFK[136.11].G "sp|P22102|PUR2_HUMAN,tr|A0A140TA71|A0A140TA71_HUMAN" 2 1503.8363 0.54 19583 20584 3 1503.835709 502.286 Trifunctional purine biosynthetic protein adenosine-3 OS=Homo sapiens OX=9606 GN=GART PE=1 SV=1 8.52 3532.5 - 1.80E+06 - - - -0.397 - 2.339 0.423 - 200.5 1 2 0 -0.0006 13 0 0 0 1.00E+07 1.86E+07 - - - 5.5597 0.8569 221125_WJC_METTL3_EV_vs_WT_F02.20585.20585.2 2.12E-05 14/20 L.EEIK[136.11]DFLLTAR[166.11].R "sp|P63173|RL38_HUMAN,tr|J3KT73|J3KT73_HUMAN,tr|J3QL01|J3QL01_HUMAN,tr|J3KSP2|J3KSP2_HUMAN" 4 1351.7466 1.01 19584 20585 2 1351.749569 676.8806 60S ribosomal protein L38 OS=Homo sapiens OX=9606 GN=RPL38 PE=1 SV=2 4.68 3532.6 - 1.47E+06 - - - 2.1698 - 2.312 0.543 - 650.3 1 1 1 0.0029 11 0 0 0 1.34E+07 1.33E+07 - - - 5.318 0.9983 221125_WJC_METTL3_EV_vs_WT_F02.20594.20594.2 0.00874 24-Aug K.EIFQTTVPYMVER.L "sp|Q9Y4A5|TRRAP_HUMAN,tr|H0Y4W2|H0Y4W2_HUMAN,tr|F2Z2U4|F2Z2U4_HUMAN" 3 1611.7967 0.99 19592 20594 2 1611.800494 806.9056 Transformation\transcription domain-associated protein OS=Homo sapiens OX=9606 GN=TRRAP PE=1 SV=3 4.53 3533.7 - 384749 - - - 2.3663 - 1.824 0.311 - 170.3 1 2 0 0.0038 13 0 0 0 3.15E+06 3.17E+06 - - - 2.8794 0.9998 221125_WJC_METTL3_EV_vs_WT_F02.20595.20595.2 0.172 20-Oct K.LVFLGLDNAGK[136.11].T "sp|Q9NR31|SAR1A_HUMAN,sp|Q9Y6B6|SAR1B_HUMAN,tr|D6RAA2|D6RAA2_HUMAN,tr|D6RD69|D6RD69_HUMAN,tr|X1WI22|X1WI22_HUMAN,tr|Q5SQT8|Q5SQT8_HUMAN,tr|D6RDB2|D6RDB2_HUMAN" 7 1153.6587 1.15 19593 20595 2 1153.658849 577.8366 GTP-binding protein SAR1a OS=Homo sapiens OX=9606 GN=SAR1A PE=1 SV=1 5.84 3533.8 - 1.07E+07 - - - 0.1647 - 2.273 0.43 - 296.6 1 2 0 0.0002 11 0 0 0 6.34E+08 5.53E+08 - - - 4.4382 0.9999 221125_WJC_METTL3_EV_vs_WT_F02.20596.20596.2 1.07E-07 13/28 K.GINTLVTYDMVPEPK.L "sp|P20674|COX5A_HUMAN,tr|H3BNX8|H3BNX8_HUMAN,tr|H3BV69|H3BV69_HUMAN" 3 1675.8491 0.71 19594 20596 2 1675.849364 838.9318 "Cytochrome c oxidase subunit 5A, mitochondrial OS=Homo sapiens OX=9606 GN=COX5A PE=1 SV=2" 4.37 3533.8 - 6.10E+06 - - - 0.1522 - 2.442 0.576 - 444.6 1 2 0 0.0003 15 0 0 0 3.70E+07 5.24E+07 - - - 5.4903 0.9582 221125_WJC_METTL3_EV_vs_WT_F02.20597.20597.2 0.753 22-Jul K.GDNITLLQSVSN.- "sp|P62304|RUXE_HUMAN,tr|A6NHK2|A6NHK2_HUMAN" 2 1259.6357 - 19595 20597 2 1259.637157 630.8251 Small nuclear ribonucleoprotein E OS=Homo sapiens OX=9606 GN=SNRPE PE=1 SV=1 3.8 3533.9 - 4.64E+06 - - - 1.121 - 1.231 0.041 - 145.1 1 2 0 0.0014 12 0 0 0 - - - - - -0.1098 0.9999 221125_WJC_METTL3_EV_vs_WT_F02.20598.20598.3 8.94E-06 Dec-60 K.EPPLSLTIHLTSPVVR[166.11].E "sp|Q12906|ILF3_HUMAN,tr|K7EQR9|K7EQR9_HUMAN,tr|K7EKY0|K7EKY0_HUMAN,tr|K7EPG3|K7EPG3_HUMAN,tr|K7EKJ9|K7EKJ9_HUMAN" 5 1768.0122 1.28 19596 20598 3 1768.011837 590.3447 Interleukin enhancer-binding factor 3 OS=Homo sapiens OX=9606 GN=ILF3 PE=1 SV=3 6.85 3533.9 - 2.53E+06 - - - -0.2279 - 2.449 0.428 - 167.1 1 2 0 -0.0004 16 0 0 0 5.25E+07 4.11E+07 - - - 5.6099 0.9999 221125_WJC_METTL3_EV_vs_WT_F02.20599.20599.3 0.00204 13/64 R.ATAAFILANEHNVALFK.H "sp|O00410|IPO5_HUMAN,tr|H0Y8C6|H0Y8C6_HUMAN" 2 1828.9836 1.14 19597 20599 3 1828.984414 610.6685 Importin-5 OS=Homo sapiens OX=9606 GN=IPO5 PE=1 SV=4 6.79 3533.9 - 2.25E+06 - - - 0.462 - 2.64 0.364 - 151.2 1 2 0 0.0008 17 0 0 0 1.42E+07 1.25E+07 - - - 5.0505 0.9998 221125_WJC_METTL3_EV_vs_WT_F02.20603.20603.2 0.0327 18-Dec R.LPEIYIQLQR.E sp|Q9H223|EHD4_HUMAN 1 1271.7238 1.88 19601 20603 2 1271.723314 636.8692 EH domain-containing protein 4 OS=Homo sapiens OX=9606 GN=EHD4 PE=1 SV=1 6 3534.4 - 1.48E+06 - - - -0.3601 - 2.401 0.385 - 749.5 1 2 0 -0.0005 10 0 0 0 3.14E+07 1.67E+07 - - - 4.3293 0.9999 221125_WJC_METTL3_EV_vs_WT_F02.20605.20605.2 1.22E-07 14/28 R.VLGVPIIVQASQAEK[136.11].N "sp|Q14498|RBM39_HUMAN,tr|H0Y4X3|H0Y4X3_HUMAN,tr|A0A0U1RQH7|A0A0U1RQH7_HUMAN,tr|Q5QP23|Q5QP23_HUMAN,tr|G3XAC6|G3XAC6_HUMAN" 5 1558.9174 1.29 19603 20605 2 1558.91863 780.466 RNA-binding protein 39 OS=Homo sapiens OX=9606 GN=RBM39 PE=1 SV=2 5.97 3534.6 - 1.04E+06 - - - 0.7935 - 2.436 0.605 - 465.6 1 2 0 0.0012 15 0 0 0 9.33E+07 7.22E+07 - - - 5.6981 0.9992 221125_WJC_METTL3_EV_vs_WT_F02.20606.20606.3 0.00545 14/48 R.NLLESYHVPELIK.D "sp|P42704|LPPRC_HUMAN,tr|A0A804HI14|A0A804HI14_HUMAN,tr|A0A804HL40|A0A804HL40_HUMAN,tr|A0A804HKJ0|A0A804HKJ0_HUMAN,tr|A0A804HKR3|A0A804HKR3_HUMAN,tr|A0A804HIN4|A0A804HIN4_HUMAN,tr|A0A804HLG8|A0A804HLG8_HUMAN,tr|A0A804HIV5|A0A804HIV5_HUMAN,tr|A0A804HHY9|A0A804HHY9_HUMAN,tr|A0A804HJH8|A0A804HJH8_HUMAN,tr|B8ZZ38|B8ZZ38_HUMAN,tr|A0A804HI40|A0A804HI40_HUMAN,tr|A0A804HJZ1|A0A804HJZ1_HUMAN,tr|C9JCA9|C9JCA9_HUMAN,tr|A0A804HIQ7|A0A804HIQ7_HUMAN,tr|A0A804HK30|A0A804HK30_HUMAN,tr|A0A804HKI2|A0A804HKI2_HUMAN,tr|A0A804HJI0|A0A804HJI0_HUMAN,tr|A0A804HIG4|A0A804HIG4_HUMAN,tr|A0A804HK02|A0A804HK02_HUMAN" 20 1553.8453 0.68 19604 20606 3 1553.849357 518.9557 "Leucine-rich PPR motif-containing protein, mitochondrial OS=Homo sapiens OX=9606 GN=LRPPRC PE=1 SV=3" 5.4 3534.7 - 1.02E+06 - - - 2.5826 - 2.141 0.331 - 188.4 1 2 0 0.004 13 0 0 0 8.41E+06 1.24E+07 - - - 4.2932 0.9977 221125_WJC_METTL3_EV_vs_WT_F02.20608.20608.3 0.000165 16/44 K.LLEPVLLLGK[136.11]ER[166.11].F "sp|P62249|RS16_HUMAN,tr|M0R210|M0R210_HUMAN,tr|M0R3H0|M0R3H0_HUMAN,tr|M0QX76|M0QX76_HUMAN,tr|M0R1M5|M0R1M5_HUMAN,tr|Q6IPX4|Q6IPX4_HUMAN" 6 1396.8773 0.73 19606 20608 3 1396.876741 466.633 40S ribosomal protein S16 OS=Homo sapiens OX=9606 GN=RPS16 PE=1 SV=2 6.14 3535 - 800951 - - - -0.3694 - 2.667 0.229 - 424.4 1 2 1 -0.0005 12 0 0 0 1.24E+07 1.71E+07 - - - 3.812 0.9889 221125_WJC_METTL3_EV_vs_WT_F02.20609.20609.3 0.0102 Sep-48 K.IGLDDEEK[136.11]LDLFR[166.11].V "sp|Q9UM54|MYO6_HUMAN,tr|A0A590UK86|A0A590UK86_HUMAN,tr|A0A590UK71|A0A590UK71_HUMAN,tr|A0A0D9SGC1|A0A0D9SGC1_HUMAN,tr|A0A0A0MRM8|A0A0A0MRM8_HUMAN,tr|A0A5F9ZI03|A0A5F9ZI03_HUMAN,tr|A0A590UK22|A0A590UK22_HUMAN,tr|A0A590UJY4|A0A590UJY4_HUMAN,tr|A0A590UJ40|A0A590UJ40_HUMAN,tr|A0A590UJ75|A0A590UJ75_HUMAN,tr|E7EW20|E7EW20_HUMAN,tr|A0A590UKB0|A0A590UKB0_HUMAN,tr|A0A1Y0BRN3|A0A1Y0BRN3_HUMAN" 13 1579.8213 3.17 19607 20609 3 1579.819249 527.6144 Unconventional myosin-VI OS=Homo sapiens OX=9606 GN=MYO6 PE=1 SV=4 4.11 3535 - 537437 - - - -1.2717 - 2.115 0.199 - 72.9 1 2 1 -0.002 13 0 0 0 1.18E+07 3.71E+06 - - - 2.789 0.9984 221125_WJC_METTL3_EV_vs_WT_F02.20611.20611.3 0.000882 Nov-36 R.SR[166.11]GFGFVLFK[136.11].E "sp|Q14103|HNRPD_HUMAN,sp|O14979|HNRDL_HUMAN,tr|H0Y8G5|H0Y8G5_HUMAN,tr|A0A087WUK2|A0A087WUK2_HUMAN,tr|D6RF44|D6RF44_HUMAN,tr|D6RBQ9|D6RBQ9_HUMAN,tr|D6RAF8|D6RAF8_HUMAN,tr|H0YA96|H0YA96_HUMAN" 8 1174.6618 1.18 19609 20611 3 1174.662128 392.5612 Heterogeneous nuclear ribonucleoprotein D0 OS=Homo sapiens OX=9606 GN=HNRNPD PE=1 SV=1 11 3535.3 - 451647 - - - 0.2929 - 1.759 0.351 - 180.5 1 2 1 0.0003 10 0 0 0 5.94E+06 5.04E+06 - - - 4.1025 0.9998 221125_WJC_METTL3_EV_vs_WT_F02.20615.20615.2 0.000574 20-Aug K.GFLEDLAPPER.S "sp|P52948|NUP98_HUMAN,tr|H7C3P6|H7C3P6_HUMAN,tr|H0YCT1|H0YCT1_HUMAN" 3 1242.6245 1.66 19612 20615 2 1242.624765 622.3195 Nuclear pore complex protein Nup98-Nup96 OS=Homo sapiens OX=9606 GN=NUP98 PE=1 SV=4 4.14 3535.8 - 1.47E+06 - - - 0.2519 - 2.106 0.39 - 262.1 1 2 0 0.0003 11 0 0 0 2.49E+07 1.50E+07 - - - 3.9363 0.9999 221125_WJC_METTL3_EV_vs_WT_F02.20616.20616.2 1.38E-06 18-Nov R.GMQDLVEDFK.N sp|P02538|K2C6A_HUMAN 1 1180.5434 171.07 19613 20616 2 1180.543074 591.279 "Keratin, type II cytoskeletal 6A OS=Homo sapiens OX=9606 GN=KRT6A PE=1 SV=3" 4.03 3535.8 - 1.00E+07 - - - -0.2973 - 2.121 0.574 - 447.6 1 2 0 -0.0003 10 0 0 0 2.40E+09 1.40E+07 - - - 5.3792 1 221125_WJC_METTL3_EV_vs_WT_F02.20619.20619.2 2.51E-09 19/34 K.VQGGALEDSQLVAGVAFK[136.11].K sp|Q99832|TCPH_HUMAN 1 1795.956 0.15 19616 20619 2 1795.954809 898.9853 T-complex protein 1 subunit eta OS=Homo sapiens OX=9606 GN=CCT7 PE=1 SV=2 4.37 3536 - 2.96E+06 - - - -0.6431 - 3.851 0.652 - 1210.3 1 2 0 -0.0012 18 0 0 0 1.01E+07 6.65E+07 - - - 7.1712 0.9999 221125_WJC_METTL3_EV_vs_WT_F02.20622.20622.2 4.08E-07 15/28 R.VLGVPIIVQASQAEK.N "sp|Q14498|RBM39_HUMAN,tr|H0Y4X3|H0Y4X3_HUMAN,tr|A0A0U1RQH7|A0A0U1RQH7_HUMAN,tr|Q5QP23|Q5QP23_HUMAN,tr|G3XAC6|G3XAC6_HUMAN" 5 1550.9032 1.29 19619 20622 2 1550.901014 776.4589 RNA-binding protein 39 OS=Homo sapiens OX=9606 GN=RBM39 PE=1 SV=2 5.97 3536.2 - 1.78E+06 - - - -1.4056 - 2.472 0.558 - 508.1 1 2 0 -0.0022 15 0 0 0 9.33E+07 7.22E+07 - - - 5.3868 0.9991 221125_WJC_METTL3_EV_vs_WT_F02.20624.20624.3 1.26 14/56 K.AILILDNDGDR[166.11]LFAK[136.11].Y "sp|P61923|COPZ1_HUMAN,tr|F8VVA7|F8VVA7_HUMAN,tr|F8W651|F8W651_HUMAN,tr|F8W156|F8W156_HUMAN,tr|F8VYZ4|F8VYZ4_HUMAN,tr|F8VUC5|F8VUC5_HUMAN,tr|F8VXB1|F8VXB1_HUMAN,tr|F8VXR1|F8VXR1_HUMAN" 8 1690.9373 2 19621 20624 3 1690.935988 564.653 Coatomer subunit zeta-1 OS=Homo sapiens OX=9606 GN=COPZ1 PE=1 SV=1 4.43 3536.5 - 981852 - - - -0.7706 - 2.912 0.296 - 189.3 1 2 1 -0.0013 15 0 0 0 6.90E+06 3.45E+06 - - - 4.6287 0.9987 221125_WJC_METTL3_EV_vs_WT_F02.20625.20625.3 0.0101 Dec-36 R.SRGFGFVLFK.E "sp|Q14103|HNRPD_HUMAN,sp|O14979|HNRDL_HUMAN,tr|H0Y8G5|H0Y8G5_HUMAN,tr|A0A087WUK2|A0A087WUK2_HUMAN,tr|D6RF44|D6RF44_HUMAN,tr|D6RBQ9|D6RBQ9_HUMAN,tr|D6RAF8|D6RAF8_HUMAN,tr|H0YA96|H0YA96_HUMAN" 8 1156.6393 1.18 19622 20625 3 1156.637424 386.5537 Heterogeneous nuclear ribonucleoprotein D0 OS=Homo sapiens OX=9606 GN=HNRNPD PE=1 SV=1 11 3536.6 - 929384 - - - -1.634 - 1.952 0.366 - 220.9 1 2 1 -0.0019 10 0 0 0 5.94E+06 5.04E+06 - - - 4.5734 0.8649 221125_WJC_METTL3_EV_vs_WT_F02.20628.20628.3 0.000223 15/68 S.LYVGDLHPDVTEAMLYEK[136.11].F "sp|Q9H361|PABP3_HUMAN,sp|Q4VXU2|PAP1L_HUMAN,sp|P11940|PABP1_HUMAN,tr|A0A7I2V3J9|A0A7I2V3J9_HUMAN,tr|A0A7I2V649|A0A7I2V649_HUMAN,tr|A0A6Q8JFT6|A0A6Q8JFT6_HUMAN,tr|E5RHG7|E5RHG7_HUMAN,tr|E5RFD8|E5RFD8_HUMAN,tr|H0YAR2|H0YAR2_HUMAN,tr|E7ERJ7|E7ERJ7_HUMAN,tr|E5RJB9|E5RJB9_HUMAN,tr|A0A7I2YQ88|A0A7I2YQ88_HUMAN,tr|E5RGC4|E5RGC4_HUMAN,tr|E5RJM8|E5RJM8_HUMAN,tr|E5RH24|E5RH24_HUMAN,tr|H0YBN4|H0YBN4_HUMAN,tr|A0A087WTT1|A0A087WTT1_HUMAN,tr|A0A7I2YQ90|A0A7I2YQ90_HUMAN,tr|A0A6Q8JFV4|A0A6Q8JFV4_HUMAN" 19 2100.0329 1.44 19625 20628 3 2100.025257 701.0182 Polyadenylate-binding protein 3 OS=Homo sapiens OX=9606 GN=PABPC3 PE=1 SV=2 4.31 3537 - 579840 - - - -3.6366 - 2.385 0.33 - 159 1 1 0 -0.0076 18 0 0 0 6.19E+06 4.31E+06 - - - 4.3815 0.9998 221125_WJC_METTL3_EV_vs_WT_F02.20632.20632.3 0.00102 Oct-56 R.LFPLIQTMHSNLAGK.L "sp|Q13310|PABP4_HUMAN,tr|A0A7I2V5W9|A0A7I2V5W9_HUMAN,tr|H0YEU6|H0YEU6_HUMAN,tr|B1ANR0|B1ANR0_HUMAN,tr|A0A7I2V4L7|A0A7I2V4L7_HUMAN,tr|A0A7I2V598|A0A7I2V598_HUMAN,tr|A0A7I2V4V6|A0A7I2V4V6_HUMAN,tr|H0Y5F5|H0Y5F5_HUMAN,tr|H0Y6X6|H0Y6X6_HUMAN" 9 1668.9021 1.43 19628 20632 3 1668.900419 557.308 Polyadenylate-binding protein 4 OS=Homo sapiens OX=9606 GN=PABPC4 PE=1 SV=1 8.76 3537.4 - 2.04E+06 - - - -1.036 - 2.031 0.362 - 58.8 1 2 0 -0.0017 15 0 0 0 4.74E+07 3.32E+07 - - - 4.4243 1 221125_WJC_METTL3_EV_vs_WT_F02.20633.20633.2 9.74E-06 17/28 R.LPAAGVGDMVMATVK.K "sp|P62829|RL23_HUMAN,tr|J3KT29|J3KT29_HUMAN,tr|B9ZVP7|B9ZVP7_HUMAN,tr|C9JD32|C9JD32_HUMAN" 4 1458.7575 0.94 19629 20633 2 1458.758783 730.386 60S ribosomal protein L23 OS=Homo sapiens OX=9606 GN=RPL23 PE=1 SV=1 5.84 3537.5 - 6.52E+06 - - - 0.909 - 3.399 0.588 - 1217.6 1 2 0 0.0013 15 0 0 0 2.53E+08 2.70E+08 - - - 6.3915 1 221125_WJC_METTL3_EV_vs_WT_F02.20634.20634.3 1.93E-08 18/68 K.VQGGALEDSQLVAGVAFK[136.11].K sp|Q99832|TCPH_HUMAN 1 1795.956 0.18 19630 20634 3 1795.95576 599.6593 T-complex protein 1 subunit eta OS=Homo sapiens OX=9606 GN=CCT7 PE=1 SV=2 4.37 3537.5 - 5.27E+06 - - - -0.1136 - 3.128 0.561 - 454.5 1 2 0 -0.0002 18 0 0 0 8.84E+06 4.84E+07 - - - 7.6342 0.9998 221125_WJC_METTL3_EV_vs_WT_F02.20635.20635.2 0.00186 16-Sep R.SPTWFGIPR.L "sp|P78347|GTF2I_HUMAN,tr|A0A494C1K3|A0A494C1K3_HUMAN" 2 1059.5502 1.37 19631 20635 2 1059.550531 530.7824 General transcription factor II-I OS=Homo sapiens OX=9606 GN=GTF2I PE=1 SV=2 9.47 3537.6 - 2.74E+06 - - - 0.3454 - 2.042 0.424 - 428 1 2 0 0.0004 9 0 0 0 3.14E+08 2.29E+08 - - - 4.238 0.9999 221125_WJC_METTL3_EV_vs_WT_F02.20636.20636.2 0.00141 15/28 K.VPGISSIEQGMTGLK[136.11].L "sp|Q7Z739|YTHD3_HUMAN,tr|A0A087X0Q1|A0A087X0Q1_HUMAN,tr|A0A024R7W5|A0A024R7W5_HUMAN,tr|A0A087WY31|A0A087WY31_HUMAN" 4 1523.8109 1.24 19632 20636 2 1523.812616 762.9127 YTH domain-containing family protein 3 OS=Homo sapiens OX=9606 GN=YTHDF3 PE=1 SV=1 5.97 3537.7 - 2.30E+06 - - - 1.1392 - 2.84 0.547 - 747.3 1 2 0 0.0017 15 0 0 0 9.06E+07 7.30E+07 - - - 5.6468 1 221125_WJC_METTL3_EV_vs_WT_F02.20637.20637.3 4.74E-07 18/64 R.ATAAFILANEHNVALFK[136.11].H "sp|O00410|IPO5_HUMAN,tr|H0Y8C6|H0Y8C6_HUMAN" 2 1836.9978 1.18 19633 20637 3 1836.998621 613.3399 Importin-5 OS=Homo sapiens OX=9606 GN=IPO5 PE=1 SV=4 6.79 3537.8 - 2.03E+06 - - - 0.4638 - 2.732 0.455 - 408.1 1 2 0 0.0009 17 0 0 0 1.47E+07 1.25E+07 - - - 6.1516 0.9997 221125_WJC_METTL3_EV_vs_WT_F02.20638.20638.2 0.000511 22-Nov K.TIVTDVFQGSMR[166.11].L "sp|Q53GS9|SNUT2_HUMAN,tr|B9A018|B9A018_HUMAN,tr|A0A087X1B2|A0A087X1B2_HUMAN" 3 1362.6841 1.39 19634 20638 2 1362.685278 682.3493 U4\U6.U5 tri-snRNP-associated protein 2 OS=Homo sapiens OX=9606 GN=USP39 PE=1 SV=2 5.5 3537.9 - 1.46E+06 - - - 0.8601 - 2.098 0.398 - 328.9 1 2 0 0.0012 12 0 0 0 8.27E+06 5.96E+06 - - - 3.9299 1 221125_WJC_METTL3_EV_vs_WT_F02.20639.20639.2 7.70E-10 14/28 K.YEQGFITDPVVLSPK.D "sp|P12268|IMDH2_HUMAN,tr|A0A7I2YQK5|A0A7I2YQK5_HUMAN,tr|H0Y4R1|H0Y4R1_HUMAN,tr|A0A7I2V2T3|A0A7I2V2T3_HUMAN,tr|E7ETK5|E7ETK5_HUMAN" 5 1691.877 0.87 19635 20639 2 1691.871519 846.9458 Inosine-5'-monophosphate dehydrogenase 2 OS=Homo sapiens OX=9606 GN=IMPDH2 PE=1 SV=2 4.37 3538 - 1.32E+06 - - - -3.2621 - 2.6 0.588 - 624.5 1 2 0 -0.0055 15 0 0 0 2.29E+07 2.64E+07 - - - 5.7314 0.8837 221125_WJC_METTL3_EV_vs_WT_F02.20640.20640.2 1.27E-05 24-Sep H.YSELTTLTSQYIK.F "sp|Q15149|PLEC_HUMAN,tr|H0YDN1|H0YDN1_HUMAN" 2 1545.7926 2.11 19636 20640 2 1545.797154 773.9036 Plectin OS=Homo sapiens OX=9606 GN=PLEC PE=1 SV=3 6 3538.1 - 1.24E+06 - - - 2.9202 - 2.14 0.274 - 183.7 1 1 0 0.0045 13 0 0 0 7.19E+06 3.41E+06 - - - 3.016 0.9989 221125_WJC_METTL3_EV_vs_WT_F02.20641.20641.3 8.29E-05 Nov-56 K.GINTLVTYDMVPEPK[136.11].L "sp|P20674|COX5A_HUMAN,tr|H3BNX8|H3BNX8_HUMAN,tr|H3BV69|H3BV69_HUMAN" 3 1683.8633 1.54 19637 20641 3 1683.854414 562.295 "Cytochrome c oxidase subunit 5A, mitochondrial OS=Homo sapiens OX=9606 GN=COX5A PE=1 SV=2" 4.37 3538.2 - 1.15E+06 - - - -5.2825 - 2.038 0.485 - 104.9 1 2 0 -0.0089 15 0 0 0 2.31E+07 1.50E+07 - - - 5.8026 0.9996 221125_WJC_METTL3_EV_vs_WT_F02.20642.20642.2 0.00777 16-Oct R.LNILDTLSK[136.11].F "sp|Q13200|PSMD2_HUMAN,tr|H7C1H2|H7C1H2_HUMAN" 2 1023.6056 0.64 19638 20642 2 1023.605123 512.8101 26S proteasome non-ATPase regulatory subunit 2 OS=Homo sapiens OX=9606 GN=PSMD2 PE=1 SV=3 5.84 3538.3 - 1.03E+06 - - - -0.4279 - 2.045 0.29 - 298.6 1 2 0 -0.0004 9 0 0 0 2.78E+07 4.33E+07 - - - 3.2525 0.9997 221125_WJC_METTL3_EV_vs_WT_F02.20644.20644.3 0.000258 18/44 K.LLEPVLLLGKER.F "sp|P62249|RS16_HUMAN,tr|M0R210|M0R210_HUMAN,tr|M0R3H0|M0R3H0_HUMAN,tr|M0QX76|M0QX76_HUMAN,tr|M0R1M5|M0R1M5_HUMAN,tr|Q6IPX4|Q6IPX4_HUMAN" 6 1378.8548 0.76 19640 20644 3 1378.854664 460.6255 40S ribosomal protein S16 OS=Homo sapiens OX=9606 GN=RPS16 PE=1 SV=2 6.14 3538.6 - 975476 - - - -0.0892 - 2.569 0.413 - 461.5 1 2 1 -0.0001 12 0 0 0 1.00E+07 1.32E+07 - - - 5.7598 0.9998 221125_WJC_METTL3_EV_vs_WT_F02.20645.20645.2 0.00116 26-Dec K.NSDLLTSPDVGLLK[136.11].L sp|P05412|JUN_HUMAN 1 1478.8072 -1 19641 20645 2 1478.806722 740.4109 Transcription factor AP-1 OS=Homo sapiens OX=9606 GN=JUN PE=1 SV=2 4.21 3538.7 - 548811 - - - -0.3057 - 2.384 0.363 - 491.6 1 2 0 -0.0005 14 0 0 0 0.00E+00 0.00E+00 - - - 3.9021 1 221125_WJC_METTL3_EV_vs_WT_F02.20650.20650.2 1.31E-08 16/28 R.LPAAGVGDMVMATVK[136.11].K "sp|P62829|RL23_HUMAN,tr|J3KT29|J3KT29_HUMAN,tr|B9ZVP7|B9ZVP7_HUMAN,tr|C9JD32|C9JD32_HUMAN" 4 1466.7717 0.95 19644 20650 2 1466.771319 734.3931 60S ribosomal protein L23 OS=Homo sapiens OX=9606 GN=RPL23 PE=1 SV=1 5.84 3539.2 - 1.17E+07 - - - -0.2304 - 3.286 0.618 - 926.6 1 2 0 -0.0003 15 0 0 0 2.58E+08 2.72E+08 - - - 6.5303 1 221125_WJC_METTL3_EV_vs_WT_F02.20651.20651.2 2.23E-05 14/28 K.LLMMAGIDDC[160.03]YTSAR[166.11].G "sp|P15880|RS2_HUMAN,tr|I3L404|I3L404_HUMAN,tr|E9PM36|E9PM36_HUMAN,tr|E9PQD7|E9PQD7_HUMAN,tr|H0YEN5|H0YEN5_HUMAN" 5 1725.7764 1.01 19645 20651 2 1725.776001 863.8955 40S ribosomal protein S2 OS=Homo sapiens OX=9606 GN=RPS2 PE=1 SV=2 4.21 3539.3 - 7.93E+06 - - - -0.2132 - 2.847 0.658 - 701.2 1 2 0 -0.0004 15 0 0 0 9.34E+07 9.26E+07 - - - 6.4732 0.9862 221125_WJC_METTL3_EV_vs_WT_F02.20652.20652.2 0.000177 22-Oct R.TMQNLEIELQSQ.L sp|P02533|K1C14_HUMAN 1 1432.6868 - 19646 20652 2 1432.684849 717.3507 "Keratin, type I cytoskeletal 14 OS=Homo sapiens OX=9606 GN=KRT14 PE=1 SV=4" 3.79 3539.3 - 2.71E+06 - - - -1.3583 - 2.133 0.452 - 254.2 1 1 0 -0.0019 12 0 0 0 - - - - - 4.3721 0.9921 221125_WJC_METTL3_EV_vs_WT_F02.20653.20653.2 0.0118 14/24 R.LNAETFGIPLRPN.R "sp|Q8ND56|LS14A_HUMAN,tr|A0A140TA66|A0A140TA66_HUMAN,tr|A0A096LP11|A0A096LP11_HUMAN,tr|A0A140TA76|A0A140TA76_HUMAN,tr|A0A0G2JQ95|A0A0G2JQ95_HUMAN" 5 1440.7725 1.17 19647 20653 2 1440.772133 721.3935 Protein LSM14 homolog A OS=Homo sapiens OX=9606 GN=LSM14A PE=1 SV=3 6 3539.4 - 2.04E+06 - - - -0.2644 - 2.826 0.404 - 599.8 1 1 0 -0.0004 13 0 0 0 6.45E+07 5.51E+07 - - - 4.6911 1 221125_WJC_METTL3_EV_vs_WT_F02.20654.20654.3 8.74E-14 19/68 R.VGDYVYFENSSSNPYLVR.R sp|O94776|MTA2_HUMAN 1 2107.9851 0.77 19648 20654 3 2107.987832 703.669 Metastasis-associated protein MTA2 OS=Homo sapiens OX=9606 GN=MTA2 PE=1 SV=1 4.37 3539.5 - 1.20E+06 - - - 1.3031 - 3.683 0.686 - 502.3 1 2 0 0.0027 18 0 0 0 1.20E+07 1.56E+07 - - - 9.4339 1 221125_WJC_METTL3_EV_vs_WT_F02.20655.20655.2 3.21E-06 13/30 R.ILYMTDEVNDPSLTIK.S sp|P00403|COX2_HUMAN 1 1850.9336 1.26 19649 20655 2 1850.935805 926.4741 Cytochrome c oxidase subunit 2 OS=Homo sapiens OX=9606 GN=MT-CO2 PE=1 SV=1 4.03 3539.7 - 828883 - - - 1.2091 - 2.669 0.604 - 425.1 1 2 0 0.0022 16 0 0 0 1.16E+07 9.23E+06 - - - 5.915 1 221125_WJC_METTL3_EV_vs_WT_F02.20656.20656.2 8.19E-10 13/30 R.ILYMTDEVNDPSLTIK[136.11].S sp|P00403|COX2_HUMAN 1 1858.9478 1.26 19650 20656 2 1858.94552 930.4812 Cytochrome c oxidase subunit 2 OS=Homo sapiens OX=9606 GN=MT-CO2 PE=1 SV=1 4.03 3539.8 - 815218 - - - -1.2087 - 2.678 0.664 - 428.2 1 2 0 -0.0022 16 0 0 0 1.16E+07 9.23E+06 - - - 6.3664 0.9998 221125_WJC_METTL3_EV_vs_WT_F02.20657.20657.2 0.00952 20-Dec K.NPLIINSIIDK[136.11].A "sp|Q9UNQ2|DIM1_HUMAN,tr|A0A494C0G7|A0A494C0G7_HUMAN,tr|B4DRY2|B4DRY2_HUMAN,tr|A0A7P0T8X7|A0A7P0T8X7_HUMAN,tr|A0A0C4DGB1|A0A0C4DGB1_HUMAN,tr|A0A7P0T967|A0A7P0T967_HUMAN,tr|A0A7P0T9J1|A0A7P0T9J1_HUMAN,tr|A0A7P0Z4I0|A0A7P0Z4I0_HUMAN,tr|A0A7P0T9Y7|A0A7P0T9Y7_HUMAN,tr|D6RCL3|D6RCL3_HUMAN" 10 1246.7376 0.95 19651 20657 2 1246.737751 624.3761 Probable dimethyladenosine transferase OS=Homo sapiens OX=9606 GN=DIMT1 PE=1 SV=1 5.84 3539.9 - 772353 - - - 0.0906 - 2.32 0.397 - 693.6 1 2 0 0.0001 11 0 0 0 6.71E+06 7.03E+06 - - - 4.2498 1 221125_WJC_METTL3_EV_vs_WT_F02.20658.20658.2 2.24E-10 20/34 K.VQGGALEDSQLVAGVAFK.K sp|Q99832|TCPH_HUMAN 1 1787.9418 0.16 19652 20658 2 1787.944709 894.9782 T-complex protein 1 subunit eta OS=Homo sapiens OX=9606 GN=CCT7 PE=1 SV=2 4.37 3540.1 - 742638 - - - 1.6471 - 3.959 0.642 - 1357.1 1 2 0 0.0029 18 0 0 0 1.01E+07 6.50E+07 - - - 7.1648 1 221125_WJC_METTL3_EV_vs_WT_F02.20659.20659.2 2.42E-12 16/34 R.VGDYVYFENSSSNPYLVR[166.11].R sp|O94776|MTA2_HUMAN 1 2117.9934 1.15 19653 20659 2 2117.986839 1060.004 Metastasis-associated protein MTA2 OS=Homo sapiens OX=9606 GN=MTA2 PE=1 SV=1 4.37 3540.2 - 665547 - - - -3.0765 - 3.258 0.743 - 805 1 2 0 -0.0065 18 0 0 0 8.78E+06 7.65E+06 - - - 7.4306 0.9991 221125_WJC_METTL3_EV_vs_WT_F02.20660.20660.2 0.0034 28-Aug K.GSVDSNWIVGATLEK.K sp|O96008|TOM40_HUMAN 1 1574.794 1.35 19654 20660 2 1574.792155 788.4043 Mitochondrial import receptor subunit TOM40 homolog OS=Homo sapiens OX=9606 GN=TOMM40 PE=1 SV=1 4.37 3540.3 - 658940 - - - -1.1951 - 1.621 0.331 - 66.2 1 2 0 -0.0019 15 0 0 0 4.72E+06 3.49E+06 - - - 2.6728 0.9998 221125_WJC_METTL3_EV_vs_WT_F02.20661.20661.2 8.87E-06 18-Oct K.DYYEILGVSR.G "sp|Q9NXW2|DJB12_HUMAN,tr|V9GYN7|V9GYN7_HUMAN,tr|J3KPS0|J3KPS0_HUMAN" 3 1213.5979 1.31 19655 20661 2 1213.595908 607.8062 DnaJ homolog subfamily B member 12 OS=Homo sapiens OX=9606 GN=DNAJB12 PE=1 SV=5 4.37 3540.5 - 632668 - - - -1.6439 - 1.861 0.527 - 268.2 1 2 0 -0.002 10 0 0 0 4.66E+06 3.55E+06 - - - 4.6665 0.9982 221125_WJC_METTL3_EV_vs_WT_F02.20662.20662.2 1.63E-06 22-Nov K.FGEAIGMGFPVK.V "sp|P78347|GTF2I_HUMAN,tr|A0A494C1K3|A0A494C1K3_HUMAN" 2 1251.6322 0.48 19656 20662 2 1251.62661 626.8234 General transcription factor II-I OS=Homo sapiens OX=9606 GN=GTF2I PE=1 SV=2 6 3540.6 - 536926 - - - -4.4502 - 2.074 0.495 - 283.3 1 2 0 -0.0056 12 0 0 0 7.21E+06 1.50E+07 - - - 4.6147 1 221125_WJC_METTL3_EV_vs_WT_F02.20664.20664.3 2.11E-06 14/48 R.GDGPIC[160.03]LVLAPTR.E "sp|Q92841|DDX17_HUMAN,sp|P17844|DDX5_HUMAN,tr|A0A7I2V5F5|A0A7I2V5F5_HUMAN,tr|J3KRZ1|J3KRZ1_HUMAN,tr|A0A7I2V507|A0A7I2V507_HUMAN,tr|A0A5H1ZRQ2|A0A5H1ZRQ2_HUMAN,tr|J3KTA4|J3KTA4_HUMAN,tr|A0A0G2JLI4|A0A0G2JLI4_HUMAN,tr|A0A1X7SBZ2|A0A1X7SBZ2_HUMAN,tr|A0A7I2V2S0|A0A7I2V2S0_HUMAN,tr|J3QRQ7|J3QRQ7_HUMAN" 11 1367.7231 1.56 19658 20664 3 1367.722666 456.915 Probable ATP-dependent RNA helicase DDX17 OS=Homo sapiens OX=9606 GN=DDX17 PE=1 SV=2 5.83 3540.9 - 507753 - - - -0.3327 - 2.679 0.495 - 284.6 1 2 0 -0.0005 13 0 0 0 4.09E+06 2.62E+06 - - - 6.7305 1 221125_WJC_METTL3_EV_vs_WT_F02.20665.20665.2 3.34E-08 16/34 R.VGDYVYFENSSSNPYLVR.R sp|O94776|MTA2_HUMAN 1 2107.9851 1.15 19659 20665 2 2107.982381 1054.9998 Metastasis-associated protein MTA2 OS=Homo sapiens OX=9606 GN=MTA2 PE=1 SV=1 4.37 3541 - 472248 - - - -1.2827 - 3.272 0.687 - 775.5 1 2 0 -0.0027 18 0 0 0 8.78E+06 7.65E+06 - - - 7.0287 0.9998 221125_WJC_METTL3_EV_vs_WT_F02.20666.20666.3 0.000207 Oct-40 R.ILVTLLHTLER.M sp|Q9BWD1|THIC_HUMAN 1 1306.7973 1.03 19660 20666 3 1306.796597 436.6064 "Acetyl-CoA acetyltransferase, cytosolic OS=Homo sapiens OX=9606 GN=ACAT2 PE=1 SV=2" 6.75 3541.1 - 329534 - - - -0.5165 - 2.104 0.334 - 141.9 1 2 0 -0.0007 11 0 0 0 2.07E+06 2.00E+06 - - - 4.3767 0.9998 221125_WJC_METTL3_EV_vs_WT_F02.20669.20669.2 6.62E-05 22-Dec R.IGFDVVTLSGTR[166.11].G "sp|Q9BSD7|NTPCR_HUMAN,tr|Q5TDF0|Q5TDF0_HUMAN" 2 1273.6906 1.09 19661 20669 2 1273.691532 637.8526 Cancer-related nucleoside-triphosphatase OS=Homo sapiens OX=9606 GN=NTPCR PE=1 SV=1 5.84 3541.5 - 8.07E+06 - - - 0.7537 - 2.608 0.432 - 476.8 1 2 0 0.001 12 0 0 0 9.41E+08 8.62E+08 - - - 4.7536 0.9999 221125_WJC_METTL3_EV_vs_WT_F02.20670.20670.2 0.000192 20-Oct R.SVYSWDIVVQR.V "sp|O15371|EIF3D_HUMAN,tr|B0QYA4|B0QYA4_HUMAN" 2 1350.6932 0.95 19662 20670 2 1350.693289 676.3539 Eukaryotic translation initiation factor 3 subunit D OS=Homo sapiens OX=9606 GN=EIF3D PE=1 SV=1 5.55 3541.5 - 5.49E+06 - - - 0.0652 - 2.308 0.482 - 392.5 1 2 0 0.0001 11 0 0 0 8.22E+07 8.61E+07 - - - 4.8636 0.9999 221125_WJC_METTL3_EV_vs_WT_F02.20671.20671.2 6.44E-05 13/22 R.IGFDVVTLSGTR.G "sp|Q9BSD7|NTPCR_HUMAN,tr|Q5TDF0|Q5TDF0_HUMAN" 2 1263.6823 1.09 19663 20671 2 1263.682705 632.8484 Cancer-related nucleoside-triphosphatase OS=Homo sapiens OX=9606 GN=NTPCR PE=1 SV=1 5.84 3541.6 - 6.59E+06 - - - 0.3189 - 2.548 0.455 - 584.1 1 2 0 0.0004 12 0 0 0 9.41E+08 8.62E+08 - - - 4.8625 1 221125_WJC_METTL3_EV_vs_WT_F02.20672.20672.3 2.31E-09 15/56 R.LPAAGVGDMVMATVK.K "sp|P62829|RL23_HUMAN,tr|J3KT29|J3KT29_HUMAN,tr|B9ZVP7|B9ZVP7_HUMAN,tr|C9JD32|C9JD32_HUMAN" 4 1458.7575 0.91 19664 20672 3 1458.7572 487.2598 60S ribosomal protein L23 OS=Homo sapiens OX=9606 GN=RPL23 PE=1 SV=1 5.84 3541.6 - 6.52E+06 - - - -0.1762 - 2.903 0.509 - 394.6 1 2 0 -0.0003 15 0 0 0 7.08E+07 7.79E+07 - - - 6.9957 0.9995 221125_WJC_METTL3_EV_vs_WT_F02.20673.20673.2 0.000924 16-Dec R.LNILDTLSK.F "sp|Q13200|PSMD2_HUMAN,tr|H7C1H2|H7C1H2_HUMAN" 2 1015.5914 0.64 19665 20673 2 1015.591099 508.803 26S proteasome non-ATPase regulatory subunit 2 OS=Homo sapiens OX=9606 GN=PSMD2 PE=1 SV=3 5.84 3541.7 - 2.89E+06 - - - -0.258 - 2.214 0.237 - 446.2 1 2 0 -0.0003 9 0 0 0 2.75E+07 4.33E+07 - - - 3.0908 0.9928 221125_WJC_METTL3_EV_vs_WT_F02.20674.20674.2 4.20E-05 24-Oct R.LNAETFGIPLR[166.11]PN.R "sp|Q8ND56|LS14A_HUMAN,tr|A0A140TA66|A0A140TA66_HUMAN,tr|A0A096LP11|A0A096LP11_HUMAN,tr|A0A140TA76|A0A140TA76_HUMAN,tr|A0A0G2JQ95|A0A0G2JQ95_HUMAN" 5 1450.7808 1.17 19666 20674 2 1450.780482 726.3977 Protein LSM14 homolog A OS=Homo sapiens OX=9606 GN=LSM14A PE=1 SV=3 6 3541.8 - 2.46E+06 - - - -0.2082 - 2.351 0.491 - 313.7 1 1 0 -0.0003 13 0 0 0 6.45E+07 5.51E+07 - - - 4.8614 0.9994 221125_WJC_METTL3_EV_vs_WT_F02.20675.20675.2 0.000489 16-Sep R.APFDLFENK.K "sp|P08238|HS90B_HUMAN,sp|Q58FF7|H90B3_HUMAN" 2 1079.5288 0.18 19667 20675 2 1079.530313 540.7717 Heat shock protein HSP 90-beta OS=Homo sapiens OX=9606 GN=HSP90AB1 PE=1 SV=4 4.37 3541.9 - 2.27E+06 - - - 1.4377 - 1.798 0.366 - 304.7 1 2 0 0.0016 9 0 0 0 1.02E+08 5.73E+08 - - - 3.4411 0.9996 221125_WJC_METTL3_EV_vs_WT_F02.20678.20678.3 0.102 Nov-40 R.SVYSWDIVVQR.V "sp|O15371|EIF3D_HUMAN,tr|B0QYA4|B0QYA4_HUMAN" 2 1350.6932 1.13 19670 20678 3 1350.693397 451.2383 Eukaryotic translation initiation factor 3 subunit D OS=Homo sapiens OX=9606 GN=EIF3D PE=1 SV=1 5.55 3542.2 - 509864 - - - 0.1451 - 2.106 0.292 - 216.8 1 2 0 0.0002 11 0 0 0 6.46E+06 5.71E+06 - - - 3.9113 0.9997 221125_WJC_METTL3_EV_vs_WT_F02.20682.20682.3 0.00117 14/56 R.LFPLIQTMHSNLAGK[136.11].L "sp|Q13310|PABP4_HUMAN,tr|A0A7I2V5W9|A0A7I2V5W9_HUMAN,tr|H0YEU6|H0YEU6_HUMAN,tr|B1ANR0|B1ANR0_HUMAN,tr|A0A7I2V4L7|A0A7I2V4L7_HUMAN,tr|A0A7I2V598|A0A7I2V598_HUMAN,tr|A0A7I2V4V6|A0A7I2V4V6_HUMAN,tr|H0Y5F5|H0Y5F5_HUMAN,tr|H0Y6X6|H0Y6X6_HUMAN" 9 1676.9163 1.43 19672 20682 3 1676.919603 559.9794 Polyadenylate-binding protein 4 OS=Homo sapiens OX=9606 GN=PABPC4 PE=1 SV=1 8.76 3542.7 - 2.08E+06 - - - 1.9411 - 2.289 0.358 - 156.5 1 2 0 0.0033 15 0 0 0 4.74E+07 3.32E+07 - - - 4.6913 0.9999 221125_WJC_METTL3_EV_vs_WT_F02.20683.20683.3 8.01E-07 14/60 R.IHFPLATYAPVISAEK[136.11].A "sp|Q6PEY2|TBA3E_HUMAN,sp|P0DPH7|TBA3C_HUMAN,sp|Q71U36|TBA1A_HUMAN,sp|P0DPH8|TBA3D_HUMAN,sp|P68366|TBA4A_HUMAN,sp|P68363|TBA1B_HUMAN,sp|Q9BQE3|TBA1C_HUMAN,tr|F8VVB9|F8VVB9_HUMAN,tr|C9JDS9|C9JDS9_HUMAN,tr|A0A1W2PQM2|A0A1W2PQM2_HUMAN,tr|F5H5D3|F5H5D3_HUMAN" 11 1763.9702 0.62 19673 20683 3 1763.973723 588.9973 Tubulin alpha-3E chain OS=Homo sapiens OX=9606 GN=TUBA3E PE=1 SV=2 6.75 3542.7 - 3.86E+06 - - - 2.0216 - 2.709 0.496 - 209.2 1 2 0 0.0036 16 0 0 0 2.79E+07 4.49E+07 - - - 6.626 1 221125_WJC_METTL3_EV_vs_WT_F02.20684.20684.3 5.76E-05 15/56 R.VLGVPIIVQASQAEK.N "sp|Q14498|RBM39_HUMAN,tr|H0Y4X3|H0Y4X3_HUMAN,tr|A0A0U1RQH7|A0A0U1RQH7_HUMAN,tr|Q5QP23|Q5QP23_HUMAN,tr|G3XAC6|G3XAC6_HUMAN" 5 1550.9032 1.34 19674 20684 3 1550.902555 517.975 RNA-binding protein 39 OS=Homo sapiens OX=9606 GN=RBM39 PE=1 SV=2 5.97 3542.8 - 2.18E+06 - - - -0.412 - 2.724 0.492 - 363.8 1 2 0 -0.0006 15 0 0 0 2.87E+07 2.13E+07 - - - 6.64 0.9998 221125_WJC_METTL3_EV_vs_WT_F02.20685.20685.2 0.000142 18-Nov R.TLIDLVTDDK.M "sp|O60315|ZEB2_HUMAN,tr|U3KQ51|U3KQ51_HUMAN,tr|E7EUW9|E7EUW9_HUMAN,tr|A0JP08|A0JP08_HUMAN,tr|A0A1B0GW50|A0A1B0GW50_HUMAN,tr|A0A1B0GV02|A0A1B0GV02_HUMAN,tr|A0A1X7SC99|A0A1X7SC99_HUMAN,tr|A0A1B0GVV8|A0A1B0GVV8_HUMAN" 8 1131.6023 1.54 19675 20685 2 1131.603172 566.8084 Zinc finger E-box-binding homeobox 2 OS=Homo sapiens OX=9606 GN=ZEB2 PE=1 SV=1 3.93 3542.9 - 1.93E+06 - - - 0.7529 - 1.97 0.46 - 353.7 1 2 0 0.0009 10 0 0 0 1.76E+07 1.14E+07 - - - 4.3309 0.9996 221125_WJC_METTL3_EV_vs_WT_F02.20687.20687.2 0.000191 20-Nov R.SLMIQTLEAVK.R "sp|Q9Y2R9|RT07_HUMAN,tr|J3QKW2|J3QKW2_HUMAN,tr|J3QLS3|J3QLS3_HUMAN,tr|J3QQS1|J3QQS1_HUMAN,tr|J3KSI8|J3KSI8_HUMAN" 5 1231.6846 1.19 19677 20687 2 1231.682079 616.8496 "28S ribosomal protein S7, mitochondrial OS=Homo sapiens OX=9606 GN=MRPS7 PE=1 SV=2" 5.72 3543.1 - 1.29E+06 - - - -2.0549 - 2.361 0.406 - 371 1 2 0 -0.0025 11 0 0 0 1.13E+07 9.49E+06 - - - 4.3629 0.9999 221125_WJC_METTL3_EV_vs_WT_F02.20688.20688.2 0.000109 20-Dec R.SLMIQTLEAVK[136.11].R "sp|Q9Y2R9|RT07_HUMAN,tr|J3QKW2|J3QKW2_HUMAN,tr|J3QLS3|J3QLS3_HUMAN,tr|J3QQS1|J3QQS1_HUMAN,tr|J3KSI8|J3KSI8_HUMAN" 5 1239.6988 1.19 19678 20688 2 1239.699012 620.8567 "28S ribosomal protein S7, mitochondrial OS=Homo sapiens OX=9606 GN=MRPS7 PE=1 SV=2" 5.72 3543.2 - 1.15E+06 - - - 0.1629 - 2.366 0.435 - 414.1 1 2 0 0.0002 11 0 0 0 1.13E+07 9.49E+06 - - - 4.5836 0.9999 221125_WJC_METTL3_EV_vs_WT_F02.20689.20689.3 0.0111 14/68 R.LLTLEVPGVTESRPSVLR.G "sp|Q9HCE1|MOV10_HUMAN,tr|Q5JR04|Q5JR04_HUMAN" 2 1965.1259 1.17 19679 20689 3 1965.124573 656.0492 Helicase MOV-10 OS=Homo sapiens OX=9606 GN=MOV10 PE=1 SV=2 6.14 3543.3 - 1.06E+06 - - - -0.6631 - 2.501 0.367 - 161.1 1 2 0 -0.0013 18 0 0 0 1.62E+07 1.39E+07 - - - 4.914 0.9998 221125_WJC_METTL3_EV_vs_WT_F02.20690.20690.3 7.70E-07 16/48 K.AFSQFSTLALHLR[166.11].L sp|Q15072|OZF_HUMAN 1 1499.8124 0.11 19680 20690 3 1499.813009 500.9447 Zinc finger protein OZF OS=Homo sapiens OX=9606 GN=ZNF146 PE=1 SV=2 9.8 3543.4 - 948658 - - - 0.394 - 2.599 0.322 - 233.2 1 2 0 0.0006 13 0 0 0 9.79E+05 9.29E+06 - - - 4.7194 0.9994 221125_WJC_METTL3_EV_vs_WT_F02.20691.20691.2 0.184 18-Oct R.TLIDLVTDDK[136.11].M "sp|O60315|ZEB2_HUMAN,tr|U3KQ51|U3KQ51_HUMAN,tr|E7EUW9|E7EUW9_HUMAN,tr|A0JP08|A0JP08_HUMAN,tr|A0A1B0GW50|A0A1B0GW50_HUMAN,tr|A0A1B0GV02|A0A1B0GV02_HUMAN,tr|A0A1X7SC99|A0A1X7SC99_HUMAN,tr|A0A1B0GVV8|A0A1B0GVV8_HUMAN" 8 1139.6165 1.9 19681 20691 2 1139.61629 570.8155 Zinc finger E-box-binding homeobox 2 OS=Homo sapiens OX=9606 GN=ZEB2 PE=1 SV=1 3.93 3543.5 - 899891 - - - -0.2018 - 1.906 0.276 - 267.3 1 2 0 -0.0002 10 0 0 0 1.76E+07 9.26E+06 - - - 2.8799 0.9995 221125_WJC_METTL3_EV_vs_WT_F02.20694.20694.2 0.00123 22-Oct R.GFPTIYFSPANK.K sp|P30101|PDIA3_HUMAN 1 1340.6765 0.22 19684 20694 2 1340.677791 671.3455 Protein disulfide-isomerase A3 OS=Homo sapiens OX=9606 GN=PDIA3 PE=1 SV=4 8.59 3543.9 - 658063 - - - 0.9719 - 2.004 0.318 - 316.7 1 2 0 0.0013 12 0 0 0 1.69E+07 7.74E+07 - - - 3.2184 1 221125_WJC_METTL3_EV_vs_WT_F02.20698.20698.2 1.32E-08 13/32 R.C[160.03]FGTVVGDTPAYLYEER.W sp|Q9H9S5|FKRP_HUMAN 1 1975.8986 2.22 19688 20698 2 1975.898652 988.9566 Fukutin-related protein OS=Homo sapiens OX=9606 GN=FKRP PE=1 SV=1 4.14 3544.5 - 350406 - - - 0.0369 - 2.62 0.738 - 474 1 2 0 0.0001 17 0 0 0 2.86E+06 1.29E+06 - - - 6.8599 1 221125_WJC_METTL3_EV_vs_WT_F02.20701.20701.2 1.16E-08 14/24 K.IGFFNQQYAEQLR[166.11].M "sp|Q8NE71|ABCF1_HUMAN,tr|Q5STZ8|Q5STZ8_HUMAN,tr|H0YGW7|H0YGW7_HUMAN" 3 1622.8081 0.67 19690 20701 2 1622.813204 812.4113 ATP-binding cassette sub-family F member 1 OS=Homo sapiens OX=9606 GN=ABCF1 PE=1 SV=2 6 3544.8 - 5.52E+06 - - - 3.1692 - 3.169 0.561 - 542 1 2 0 0.0051 13 0 0 0 3.42E+07 5.14E+07 - - - 6.1432 0.9999 221125_WJC_METTL3_EV_vs_WT_F02.20704.20704.2 2.42E-05 16-Oct R.SPTWFGIPR[166.11].L "sp|P78347|GTF2I_HUMAN,tr|A0A494C1K3|A0A494C1K3_HUMAN" 2 1069.5584 1.37 19692 20704 2 1069.55909 535.7865 General transcription factor II-I OS=Homo sapiens OX=9606 GN=GTF2I PE=1 SV=2 9.47 3545.1 - 2.16E+07 - - - 0.6124 - 1.965 0.507 - 536.3 1 2 0 0.0007 9 0 0 0 3.14E+08 2.29E+08 - - - 4.7397 1 221125_WJC_METTL3_EV_vs_WT_F02.20708.20708.3 3.47E-06 15/48 K.LTLHVGDGFEFMK[136.11].Q "sp|P19623|SPEE_HUMAN,tr|K7EQ47|K7EQ47_HUMAN" 2 1500.7526 0.21 19696 20708 3 1500.752355 501.2582 Spermidine synthase OS=Homo sapiens OX=9606 GN=SRM PE=1 SV=1 5.32 3545.4 - 1.21E+06 - - - -0.1872 - 2.119 0.536 - 168.4 1 2 0 -0.0003 13 0 0 0 2.13E+06 1.00E+07 - - - 6.5518 0.9511 221125_WJC_METTL3_EV_vs_WT_F02.20710.20710.2 0.0296 20-Aug F.NLFVGNLNFNK[136.11].S "sp|P19338|NUCL_HUMAN,tr|A0A7I2V506|A0A7I2V506_HUMAN,tr|A0A7I2V699|A0A7I2V699_HUMAN,tr|A0A7I2V2U7|A0A7I2V2U7_HUMAN,tr|A0A7I2V3F3|A0A7I2V3F3_HUMAN,tr|A0A7I2V428|A0A7I2V428_HUMAN,tr|A0A7I2V349|A0A7I2V349_HUMAN,tr|H7BY16|H7BY16_HUMAN,tr|A0A7I2V5M5|A0A7I2V5M5_HUMAN,tr|A0A7I2V2S8|A0A7I2V2S8_HUMAN,tr|C9JLB1|C9JLB1_HUMAN" 11 1286.6863 0.04 19698 20710 2 1286.686257 644.3504 Nucleolin OS=Homo sapiens OX=9606 GN=NCL PE=1 SV=3 8.75 3545.7 - 676177 - - - -0.0109 - 1.545 0.31 - 108.4 1 1 0 0 11 0 0 0 2.17E+05 4.84E+06 - - - 2.5075 0.9994 221125_WJC_METTL3_EV_vs_WT_F02.20714.20714.2 3.17E-07 15/28 K.YEQGFITDPVVLSPK[136.11].D "sp|P12268|IMDH2_HUMAN,tr|A0A7I2YQK5|A0A7I2YQK5_HUMAN,tr|H0Y4R1|H0Y4R1_HUMAN,tr|A0A7I2V2T3|A0A7I2V2T3_HUMAN,tr|E7ETK5|E7ETK5_HUMAN" 5 1699.8912 0.94 19701 20714 2 1699.886142 850.9529 Inosine-5'-monophosphate dehydrogenase 2 OS=Homo sapiens OX=9606 GN=IMPDH2 PE=1 SV=2 4.37 3546.3 - 881078 - - - -2.9978 - 2.5 0.477 - 624.1 1 2 0 -0.0051 15 0 0 0 2.24E+07 2.39E+07 - - - 4.8153 0.9999 221125_WJC_METTL3_EV_vs_WT_F02.20716.20716.3 2.90E-06 16/52 K.AFDLIVDRPVTLVR.E "sp|O96000|NDUBA_HUMAN,tr|H3BPJ9|H3BPJ9_HUMAN,tr|H3BV16|H3BV16_HUMAN" 3 1612.9301 1.64 19702 20716 3 1612.931473 538.6506 NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 10 OS=Homo sapiens OX=9606 GN=NDUFB10 PE=1 SV=3 6.01 3546.5 - 6.04E+06 - - - 0.8655 - 2.515 0.441 - 332.6 1 2 0 0.0014 14 0 0 0 9.40E+07 5.75E+07 - - - 5.9073 1 221125_WJC_METTL3_EV_vs_WT_F02.20717.20717.3 2.75E-07 14/56 R.LPAAGVGDMVMATVK[136.11].K "sp|P62829|RL23_HUMAN,tr|J3KT29|J3KT29_HUMAN,tr|B9ZVP7|B9ZVP7_HUMAN,tr|C9JD32|C9JD32_HUMAN" 4 1466.7717 0.92 19703 20717 3 1466.771721 489.9312 60S ribosomal protein L23 OS=Homo sapiens OX=9606 GN=RPL23 PE=1 SV=1 5.84 3546.5 - 4.27E+06 - - - 0.0436 - 2.695 0.548 - 320.5 1 2 0 0.0001 15 0 0 0 7.24E+07 7.84E+07 - - - 7.2366 0.9999 221125_WJC_METTL3_EV_vs_WT_F02.20718.20718.2 2.23E-06 14/22 R.GVGAEPLLPWNR[166.11].M sp|Q9H0D6|XRN2_HUMAN 1 1317.7069 1.26 19704 20718 2 1317.706548 659.8607 5'-3' exoribonuclease 2 OS=Homo sapiens OX=9606 GN=XRN2 PE=1 SV=1 6 3546.6 - 4.37E+06 - - - -0.2595 - 2.66 0.501 - 619.5 1 2 0 -0.0003 12 0 0 0 3.48E+08 2.76E+08 - - - 5.3154 0.9999 221125_WJC_METTL3_EV_vs_WT_F02.20719.20719.2 2.65E-05 15/22 R.GVGAEPLLPWNR.M sp|Q9H0D6|XRN2_HUMAN 1 1307.6986 1.26 19705 20719 2 1307.698603 654.8566 5'-3' exoribonuclease 2 OS=Homo sapiens OX=9606 GN=XRN2 PE=1 SV=1 6 3546.6 - 3.60E+06 - - - -0.013 - 2.723 0.499 - 636.5 1 2 0 0 12 0 0 0 3.49E+08 2.76E+08 - - - 5.3623 1 221125_WJC_METTL3_EV_vs_WT_F02.20720.20720.3 3.26E-07 16/60 R.IHFPLATYAPVISAEK.A "sp|Q6PEY2|TBA3E_HUMAN,sp|P0DPH7|TBA3C_HUMAN,sp|Q71U36|TBA1A_HUMAN,sp|P0DPH8|TBA3D_HUMAN,sp|P68366|TBA4A_HUMAN,sp|P68363|TBA1B_HUMAN,sp|Q9BQE3|TBA1C_HUMAN,tr|F8VVB9|F8VVB9_HUMAN,tr|C9JDS9|C9JDS9_HUMAN,tr|A0A1W2PQM2|A0A1W2PQM2_HUMAN,tr|F5H5D3|F5H5D3_HUMAN" 11 1755.956 0.62 19706 20720 3 1755.959115 586.3259 Tubulin alpha-3E chain OS=Homo sapiens OX=9606 GN=TUBA3E PE=1 SV=2 6.75 3546.7 - 2.91E+06 - - - 1.7985 - 3.087 0.565 - 298.4 1 2 0 0.0032 16 0 0 0 3.30E+07 5.30E+07 - - - 7.7306 0.9217 221125_WJC_METTL3_EV_vs_WT_F02.20723.20723.2 0.152 18-Aug R.TLLEQLDDDQ.- "sp|O75400|PR40A_HUMAN,tr|A0A7N4I394|A0A7N4I394_HUMAN" 2 1188.551 - 19709 20723 2 1188.559349 595.2828 Pre-mRNA-processing factor 40 homolog A OS=Homo sapiens OX=9606 GN=PRPF40A PE=1 SV=2 3.37 3547 - 1.67E+06 - - - 7.0136 - 1.408 0.3 - 218.7 1 2 0 0.0083 10 0 0 0 - - - - - 2.2093 0.9999 221125_WJC_METTL3_EV_vs_WT_F02.20726.20726.2 0.000504 13/20 K.LMEWTSLQNMR.E "sp|P48594|SPB4_HUMAN,sp|P29508|SPB3_HUMAN,tr|H0Y5H9|H0Y5H9_HUMAN" 3 1407.6639 0.67 19712 20726 2 1407.664518 704.8392 Serpin B4 OS=Homo sapiens OX=9606 GN=SERPINB4 PE=1 SV=2 6 3547.4 - 1.17E+06 - - - 0.4454 - 2.619 0.503 - 741.7 1 2 0 0.0006 11 0 0 0 2.60E+07 3.90E+07 - - - 5.3605 0.9996 221125_WJC_METTL3_EV_vs_WT_F02.20727.20727.2 0.000877 26-Nov K.ETLVFPPEVPISEK.A sp|Q9Y2H1|ST38L_HUMAN 1 1583.8447 1.58 19713 20727 2 1583.846125 792.9296 Serine\threonine-protein kinase 38-like OS=Homo sapiens OX=9606 GN=STK38L PE=1 SV=3 4.25 3547.5 - 1.13E+06 - - - 0.9149 - 2.006 0.361 - 286.9 1 2 0 0.0014 14 0 0 0 4.99E+07 3.15E+07 - - - 3.4538 0.9994 221125_WJC_METTL3_EV_vs_WT_F02.20728.20728.3 0.0137 13/44 R.IGFDVVTLSGTR[166.11].G "sp|Q9BSD7|NTPCR_HUMAN,tr|Q5TDF0|Q5TDF0_HUMAN" 2 1273.6906 1.11 19714 20728 3 1273.689792 425.5708 Cancer-related nucleoside-triphosphatase OS=Homo sapiens OX=9606 GN=NTPCR PE=1 SV=1 5.84 3547.6 - 1.10E+06 - - - -0.6124 - 1.928 0.298 - 212.2 1 2 0 -0.0008 12 0 0 0 6.93E+06 6.25E+06 - - - 3.6819 0.9997 221125_WJC_METTL3_EV_vs_WT_F02.20731.20731.3 0.000801 Nov-44 R.IGFDVVTLSGTR.G "sp|Q9BSD7|NTPCR_HUMAN,tr|Q5TDF0|Q5TDF0_HUMAN" 2 1263.6823 1.11 19717 20731 3 1263.683711 422.2347 Cancer-related nucleoside-triphosphatase OS=Homo sapiens OX=9606 GN=NTPCR PE=1 SV=1 5.84 3548 - 973297 - - - 1.115 - 1.949 0.35 - 149.3 1 2 0 0.0014 12 0 0 0 6.93E+06 6.25E+06 - - - 4.2915 0.9953 221125_WJC_METTL3_EV_vs_WT_F02.20732.20732.2 0.000196 28-Nov R.IATLGYLPTQQDVLR.V "sp|P29992|GNA11_HUMAN,tr|A0A087WVZ3|A0A087WVZ3_HUMAN,tr|K7EL62|K7EL62_HUMAN" 3 1686.9305 1.05 19718 20732 2 1686.940027 844.4725 Guanine nucleotide-binding protein subunit alpha-11 OS=Homo sapiens OX=9606 GN=GNA11 PE=1 SV=2 5.84 3548.1 - 794398 - - - 5.6647 - 2.377 0.449 - 249.9 1 2 0 0.0096 15 0 0 0 6.53E+06 6.23E+06 - - - 4.483 0.9974 221125_WJC_METTL3_EV_vs_WT_F02.20733.20733.2 0.000625 22-Dec R.VIQEGLEGLVLK.D sp|P49916|DNLI3_HUMAN 1 1296.7653 2.2 19719 20733 2 1296.759936 649.3899 DNA ligase 3 OS=Homo sapiens OX=9606 GN=LIG3 PE=1 SV=2 4.53 3548.2 - 771887 - - - -4.1388 - 2.156 0.368 - 352.9 1 2 0 -0.0054 12 0 0 0 9.92E+06 4.50E+06 - - - 3.7788 0.9917 221125_WJC_METTL3_EV_vs_WT_F02.20734.20734.2 0.000561 24-Nov R.IPSGAFEDLENLK.Y "sp|Q92626|PXDN_HUMAN,tr|C9J4I9|C9J4I9_HUMAN,tr|H7C300|H7C300_HUMAN,tr|H7C1W1|H7C1W1_HUMAN" 4 1431.7246 12.19 19720 20734 2 1431.730669 716.8696 Peroxidasin homolog OS=Homo sapiens OX=9606 GN=PXDN PE=1 SV=2 4.14 3548.4 - 538470 - - - 4.2669 - 1.617 0.325 - 188.6 1 2 0 0.0061 13 0 0 0 6.01E+06 4.93E+05 - - - 2.6729 0.9999 221125_WJC_METTL3_EV_vs_WT_F02.20737.20737.2 1.02E-06 18-Nov R.NLDFQDVLDK.L sp|Q9Y3I0|RTCB_HUMAN 1 1205.5928 1.36 19722 20737 2 1205.592661 603.8037 RNA-splicing ligase RtcB homolog OS=Homo sapiens OX=9606 GN=RTCB PE=1 SV=1 3.93 3548.6 - 1.35E+07 - - - -0.1302 - 2.26 0.535 - 400.1 1 2 0 -0.0002 10 0 0 0 1.49E+08 1.09E+08 - - - 5.2684 1 221125_WJC_METTL3_EV_vs_WT_F02.20739.20739.3 1.16E-06 15/56 R.GTVAYVGATLFATGK.W "sp|Q14203|DCTN1_HUMAN,tr|C9JTE5|C9JTE5_HUMAN,tr|A0A804CDA6|A0A804CDA6_HUMAN,tr|C9JJN7|C9JJN7_HUMAN,tr|E7EX90|E7EX90_HUMAN,tr|C9JJD0|C9JJD0_HUMAN,tr|A0A7P0Z4C3|A0A7P0Z4C3_HUMAN,tr|Q6AWB1|Q6AWB1_HUMAN,tr|C9JZA4|C9JZA4_HUMAN,tr|E9PCY0|E9PCY0_HUMAN,tr|C9J1B7|C9J1B7_HUMAN,tr|C9JKG6|C9JKG6_HUMAN" 12 1454.7769 2.47 19724 20739 3 1454.775839 485.9329 Dynactin subunit 1 OS=Homo sapiens OX=9606 GN=DCTN1 PE=1 SV=3 8.59 3548.7 - 6.53E+06 - - - -0.7499 - 2.586 0.486 - 338.6 1 2 0 -0.0011 15 0 0 0 1.94E+07 7.85E+06 - - - 6.4373 1 221125_WJC_METTL3_EV_vs_WT_F02.20741.20741.3 8.77E-07 14/56 R.GTVAYVGATLFATGK[136.11].W "sp|Q14203|DCTN1_HUMAN,tr|C9JTE5|C9JTE5_HUMAN,tr|A0A804CDA6|A0A804CDA6_HUMAN,tr|C9JJN7|C9JJN7_HUMAN,tr|E7EX90|E7EX90_HUMAN,tr|C9JJD0|C9JJD0_HUMAN,tr|A0A7P0Z4C3|A0A7P0Z4C3_HUMAN,tr|Q6AWB1|Q6AWB1_HUMAN,tr|C9JZA4|C9JZA4_HUMAN,tr|E9PCY0|E9PCY0_HUMAN,tr|C9J1B7|C9J1B7_HUMAN,tr|C9JKG6|C9JKG6_HUMAN" 12 1462.7911 3.36 19726 20741 3 1462.79113 488.6043 Dynactin subunit 1 OS=Homo sapiens OX=9606 GN=DCTN1 PE=1 SV=3 8.59 3548.8 - 2.76E+06 - - - 0 - 2.628 0.469 - 274.7 1 2 0 0 15 0 0 0 6.12E+07 1.82E+07 - - - 6.2901 0.9998 221125_WJC_METTL3_EV_vs_WT_F02.20743.20743.2 9.32E-07 20-Dec K.VTDDLVC[160.03]LVYK.T sp|P49458|SRP09_HUMAN 1 1323.6744 1.03 19728 20743 2 1323.671731 662.8445 Signal recognition particle 9 kDa protein OS=Homo sapiens OX=9606 GN=SRP9 PE=1 SV=2 4.21 3549 - 2.37E+06 - - - -2.0458 - 2.365 0.533 - 584.8 1 2 0 -0.0027 11 0 0 0 2.64E+08 2.57E+08 - - - 5.3055 1 221125_WJC_METTL3_EV_vs_WT_F02.20744.20744.3 1.05E-06 16/52 R.IHALPESVSIFSLK.E "sp|Q00537|CDK17_HUMAN,tr|F5H6Z0|F5H6Z0_HUMAN" 2 1539.8661 0.43 19729 20744 3 1539.865264 514.296 Cyclin-dependent kinase 17 OS=Homo sapiens OX=9606 GN=CDK17 PE=1 SV=2 6.75 3549 - 2.29E+06 - - - -0.5299 - 2.869 0.566 - 437.8 1 2 0 -0.0008 14 0 0 0 1.32E+07 3.06E+07 - - - 7.6511 1 221125_WJC_METTL3_EV_vs_WT_F02.20745.20745.2 2.13E-06 17/26 K.NIYVLQELDNPGAK[136.11].R "sp|P12956|XRCC6_HUMAN,tr|B1AHC9|B1AHC9_HUMAN" 2 1580.829 1.21 19730 20745 2 1580.825346 791.4218 X-ray repair cross-complementing protein 6 OS=Homo sapiens OX=9606 GN=XRCC6 PE=1 SV=2 4.37 3549.2 - 2.19E+06 - - - -2.2937 - 3.098 0.595 - 866.6 1 2 0 -0.0036 14 0 0 0 1.36E+08 1.12E+08 - - - 6.2721 0.9998 221125_WJC_METTL3_EV_vs_WT_F02.20746.20746.2 8.26E-05 18-Nov R.APELFSYIAK.N "sp|Q8IZH2|XRN1_HUMAN,tr|H7C5E4|H7C5E4_HUMAN" 2 1137.607 1.06 19731 20746 2 1137.60541 569.8108 5'-3' exoribonuclease 1 OS=Homo sapiens OX=9606 GN=XRN1 PE=1 SV=1 6.05 3549.3 - 1.80E+06 - - - -1.4073 - 2.251 0.46 - 512.7 1 2 0 -0.0016 10 0 0 0 6.14E+07 5.79E+07 - - - 4.7029 0.9997 221125_WJC_METTL3_EV_vs_WT_F02.20748.20748.2 6.04E-07 15/24 R.VVAEPVELAQEFR.K sp|O75489|NDUS3_HUMAN 1 1485.7827 1.47 19733 20748 2 1485.778815 743.8986 "NADH dehydrogenase [ubiquinone] iron-sulfur protein 3, mitochondrial OS=Homo sapiens OX=9606 GN=NDUFS3 PE=1 SV=1" 4.25 3549.5 - 1.55E+06 - - - -2.6444 - 2.546 0.56 - 377.8 1 2 0 -0.0039 13 0 0 0 1.21E+08 8.20E+07 - - - 5.5744 1 221125_WJC_METTL3_EV_vs_WT_F02.20751.20751.2 8.11E-10 18/30 R.LITIEINPDC[160.03]AAITQR[166.11].M "sp|P21964|COMT_HUMAN,tr|E7EUU8|E7EUU8_HUMAN,tr|E7EMS6|E7EMS6_HUMAN,tr|F8WBW9|F8WBW9_HUMAN,tr|H7BZ45|H7BZ45_HUMAN,tr|A0A7I2V3G7|A0A7I2V3G7_HUMAN,tr|A0A7I2V370|A0A7I2V370_HUMAN" 7 1836.9643 1.39 19736 20751 2 1836.96091 919.4894 Catechol O-methyltransferase OS=Homo sapiens OX=9606 GN=COMT PE=1 SV=2 4.37 3549.9 - 860070 - - - -1.8476 - 3.51 0.674 - 1035.4 1 2 0 -0.0034 16 0 0 0 8.27E+06 5.95E+06 - - - 7.1051 0.9999 221125_WJC_METTL3_EV_vs_WT_F02.20757.20757.2 2.18E-08 14/26 K.NIYVLQELDNPGAK.R "sp|P12956|XRCC6_HUMAN,tr|B1AHC9|B1AHC9_HUMAN" 2 1572.8148 1.21 19741 20757 2 1572.814279 787.4147 X-ray repair cross-complementing protein 6 OS=Homo sapiens OX=9606 GN=XRCC6 PE=1 SV=2 4.37 3550.5 - 6.80E+06 - - - -0.3135 - 2.79 0.493 - 589.8 1 2 0 -0.0005 14 0 0 0 1.36E+08 1.12E+08 - - - 5.2569 0.8375 221125_WJC_METTL3_EV_vs_WT_F02.20758.20758.2 7.05E-09 24-Dec H.SLGYGFVNYVTAK.D "sp|Q15717|ELAV1_HUMAN,tr|M0QZR9|M0QZR9_HUMAN" 2 1417.7242 2.09 19742 20758 2 1417.732158 709.8694 ELAV-like protein 1 OS=Homo sapiens OX=9606 GN=ELAVL1 PE=1 SV=2 8.22 3550.5 - 6.47E+06 - - - 5.6372 - 2.292 0.536 - 352.1 1 1 0 0.008 13 0 0 0 3.72E+07 1.78E+07 - - - 5.1261 1 221125_WJC_METTL3_EV_vs_WT_F02.20760.20760.2 6.45E-09 13/28 K.VLGLSQGSVSDMLSR[166.11].P "sp|P39880|CUX1_HUMAN,sp|O14529|CUX2_HUMAN,tr|A0A2R8Y852|A0A2R8Y852_HUMAN,tr|A0A2R8YDI1|A0A2R8YDI1_HUMAN" 4 1557.806 1.22 19744 20760 2 1557.803476 779.9103 Homeobox protein cut-like 1 OS=Homo sapiens OX=9606 GN=CUX1 PE=1 SV=3 5.81 3550.6 - 5.24E+06 - - - -1.6279 - 2.75 0.648 - 452.2 1 1 0 -0.0025 15 0 0 0 5.48E+07 4.48E+07 - - - 6.3134 0.9998 221125_WJC_METTL3_EV_vs_WT_F02.20761.20761.3 0.00167 13/44 R.FYTLIPHDFGMK.K "sp|P09874|PARP1_HUMAN,tr|A0A7I2V3E1|A0A7I2V3E1_HUMAN" 2 1467.7221 0.94 19745 20761 3 1467.720863 490.248 Poly [ADP-ribose] polymerase 1 OS=Homo sapiens OX=9606 GN=PARP1 PE=1 SV=4 6.74 3550.6 - 4.81E+06 - - - -0.8142 - 2.157 0.37 - 163.2 1 2 0 -0.0012 12 0 0 0 9.81E+07 1.04E+08 - - - 4.7956 1 221125_WJC_METTL3_EV_vs_WT_F02.20762.20762.2 6.33E-08 14/28 K.SPFSVAVSPSLDLSK[136.11].L "sp|P21333|FLNA_HUMAN,tr|A0A7P0NMY4|A0A7P0NMY4_HUMAN,tr|Q60FE5|Q60FE5_HUMAN" 3 1540.8228 0.84 19746 20762 2 1540.821073 771.4187 Filamin-A OS=Homo sapiens OX=9606 GN=FLNA PE=1 SV=4 5.55 3550.7 - 4.11E+06 - - - -1.1364 - 3.05 0.621 - 588.1 1 2 0 -0.0018 15 0 0 0 4.10E+07 4.88E+07 - - - 6.3688 1 221125_WJC_METTL3_EV_vs_WT_F02.20763.20763.2 4.65E-06 14/24 R.FSGSGSGTDFTLK.L "sp|A2NJV5|KV229_HUMAN,sp|A0A087WW87|KV240_HUMAN,sp|P06310|KV230_HUMAN,sp|A0A075B6S2|KVD29_HUMAN,sp|P01614|KVD40_HUMAN,sp|P01615|KVD28_HUMAN,sp|A0A075B6S6|KVD30_HUMAN,sp|A0A075B6P5|KV228_HUMAN,sp|A0A0A0MRZ7|KVD26_HUMAN" 9 1302.6092 281.75 19747 20763 2 1302.609917 652.3119 Immunoglobulin kappa variable 2-29 OS=Homo sapiens OX=9606 GN=IGKV2-29 PE=3 SV=2 5.84 3550.7 - 3.67E+06 - - - 0.5535 - 2.767 0.641 - 394.5 1 2 0 0.0007 13 0 0 0 5.81E+07 2.06E+05 - - - 6.3873 0.9998 221125_WJC_METTL3_EV_vs_WT_F02.20764.20764.2 7.91E-06 28-Dec R.GTVAYVGATLFATGK[136.11].W "sp|Q14203|DCTN1_HUMAN,tr|C9JTE5|C9JTE5_HUMAN,tr|A0A804CDA6|A0A804CDA6_HUMAN,tr|C9JJN7|C9JJN7_HUMAN,tr|E7EX90|E7EX90_HUMAN,tr|C9JJD0|C9JJD0_HUMAN,tr|A0A7P0Z4C3|A0A7P0Z4C3_HUMAN,tr|Q6AWB1|Q6AWB1_HUMAN,tr|C9JZA4|C9JZA4_HUMAN,tr|E9PCY0|E9PCY0_HUMAN,tr|C9J1B7|C9J1B7_HUMAN,tr|C9JKG6|C9JKG6_HUMAN" 12 1462.7911 2.54 19748 20764 2 1462.788665 732.4028 Dynactin subunit 1 OS=Homo sapiens OX=9606 GN=DCTN1 PE=1 SV=3 8.59 3550.8 - 3.31E+06 - - - -1.6851 - 2.639 0.457 - 216.2 1 2 0 -0.0025 15 0 0 0 6.96E+07 2.74E+07 - - - 4.8014 0.9992 221125_WJC_METTL3_EV_vs_WT_F02.20765.20765.2 0.00039 18-Dec R.APELFSYIAK[136.11].N "sp|Q8IZH2|XRN1_HUMAN,tr|H7C5E4|H7C5E4_HUMAN" 2 1145.6212 1.09 19749 20765 2 1145.61754 573.8179 5'-3' exoribonuclease 1 OS=Homo sapiens OX=9606 GN=XRN1 PE=1 SV=1 6.05 3550.9 - 3.05E+06 - - - -3.2044 - 2.135 0.46 - 513.8 1 2 0 -0.0037 10 0 0 0 6.72E+07 6.17E+07 - - - 4.5545 0.9999 221125_WJC_METTL3_EV_vs_WT_F02.20766.20766.2 2.05E-06 22-Dec K.NVGQFSGFPFEK.G "sp|P35659|DEK_HUMAN,tr|H0Y8X0|H0Y8X0_HUMAN,tr|H0Y993|H0Y993_HUMAN,tr|A0A494C028|A0A494C028_HUMAN,tr|D6RDA2|D6RDA2_HUMAN,tr|B4DFG0|B4DFG0_HUMAN" 6 1355.651 1.47 19750 20766 2 1355.651623 678.8328 Protein DEK OS=Homo sapiens OX=9606 GN=DEK PE=1 SV=1 6 3551 - 2.04E+06 - - - 0.4588 - 2.354 0.517 - 332.4 1 2 0 0.0006 12 0 0 0 1.58E+08 1.07E+08 - - - 5.112 0.9994 221125_WJC_METTL3_EV_vs_WT_F02.20768.20768.2 0.00275 14/30 R.VLVSGLPPSGSWQDLK.D sp|Q13242|SRSF9_HUMAN 1 1681.9039 4.2 19752 20768 2 1681.900675 841.9592 Serine\arginine-rich splicing factor 9 OS=Homo sapiens OX=9606 GN=SRSF9 PE=1 SV=1 5.81 3551.2 - 1.23E+06 - - - -1.9306 - 2.051 0.37 - 321.3 1 2 0 -0.0032 16 0 0 0 1.02E+07 2.43E+06 - - - 3.5388 0.9999 221125_WJC_METTL3_EV_vs_WT_F02.20771.20771.3 8.09E-05 19/44 K.VWDLFPEADK[136.11]VR[166.11].T "sp|Q99613|EIF3C_HUMAN,sp|B5ME19|EIFCL_HUMAN" 2 1491.7841 1.14 19754 20771 3 1491.784153 498.2686 Eukaryotic translation initiation factor 3 subunit C OS=Homo sapiens OX=9606 GN=EIF3C PE=1 SV=1 4.56 3551.6 - 1.77E+06 - - - 0.0456 - 2.901 0.483 - 539.9 1 2 1 0.0001 12 0 0 0 4.01E+07 3.53E+07 - - - 6.8771 0.9999 221125_WJC_METTL3_EV_vs_WT_F02.20774.20774.2 1.58E-06 22-Sep R.EAPVDVLTQIGR.S sp|Q9BVC6|TM109_HUMAN 1 1296.7038 1.19 19757 20774 2 1296.704587 649.3592 Transmembrane protein 109 OS=Homo sapiens OX=9606 GN=TMEM109 PE=1 SV=1 4.37 3551.7 - 2.78E+06 - - - 0.6339 - 1.997 0.527 - 272.6 1 2 0 0.0008 12 0 0 0 1.31E+08 1.10E+08 - - - 4.753 0.9788 221125_WJC_METTL3_EV_vs_WT_F02.20776.20776.3 0.00911 14/56 L.VEPFGVISNHLILNK[136.11].L "sp|P43243|MATR3_HUMAN,tr|D6RE02|D6RE02_HUMAN,tr|B3KM87|B3KM87_HUMAN,tr|A8MXP9|A8MXP9_HUMAN,tr|D6R991|D6R991_HUMAN,tr|D6RBK5|D6RBK5_HUMAN,tr|A0A0R4J2E8|A0A0R4J2E8_HUMAN,tr|D6RIA2|D6RIA2_HUMAN,tr|H0Y8T4|H0Y8T4_HUMAN,tr|D6REM6|D6REM6_HUMAN,tr|D6RBI2|D6RBI2_HUMAN" 11 1686.9548 1.41 19759 20776 3 1686.953877 563.3256 Matrin-3 OS=Homo sapiens OX=9606 GN=MATR3 PE=1 SV=2 6.72 3552 - 2.29E+06 - - - -0.572 - 2.661 0.309 - 144.8 1 1 0 -0.001 15 0 0 0 3.13E+07 2.22E+07 - - - 4.5386 0.9997 221125_WJC_METTL3_EV_vs_WT_F02.20777.20777.2 0.00508 22-Dec K.NVLGLVPQALPK[136.11].A "sp|Q8N1G0|ZN687_HUMAN,tr|H0Y5I5|H0Y5I5_HUMAN,tr|F8WCX2|F8WCX2_HUMAN" 3 1255.7744 1.04 19760 20777 2 1255.775144 628.8945 Zinc finger protein 687 OS=Homo sapiens OX=9606 GN=ZNF687 PE=1 SV=1 8.75 3552.1 - 1.98E+06 - - - 0.6259 - 2.01 0.382 - 319.3 1 2 0 0.0008 12 0 0 0 1.86E+07 1.78E+07 - - - 3.6991 1 221125_WJC_METTL3_EV_vs_WT_F02.20778.20778.3 1.12E-08 20/48 R.VVAEPVELAQEFR.K sp|O75489|NDUS3_HUMAN 1 1485.7827 1.35 19761 20778 3 1485.781746 496.2682 "NADH dehydrogenase [ubiquinone] iron-sulfur protein 3, mitochondrial OS=Homo sapiens OX=9606 GN=NDUFS3 PE=1 SV=1" 4.25 3552.2 - 1.96E+06 - - - -0.6717 - 3.515 0.571 - 925.9 1 2 0 -0.001 13 0 0 0 3.15E+07 2.34E+07 - - - 8.314 1 221125_WJC_METTL3_EV_vs_WT_F02.20780.20780.2 1.48E-09 14/30 R.LITIEINPDC[160.03]AAITQR.M "sp|P21964|COMT_HUMAN,tr|E7EUU8|E7EUU8_HUMAN,tr|E7EMS6|E7EMS6_HUMAN,tr|F8WBW9|F8WBW9_HUMAN,tr|H7BZ45|H7BZ45_HUMAN,tr|A0A7I2V3G7|A0A7I2V3G7_HUMAN,tr|A0A7I2V370|A0A7I2V370_HUMAN" 7 1826.956 1.39 19763 20780 2 1826.956142 914.4853 Catechol O-methyltransferase OS=Homo sapiens OX=9606 GN=COMT PE=1 SV=2 4.37 3552.5 - 1.38E+06 - - - 0.0591 - 3.132 0.571 - 552.2 1 2 0 0.0001 16 0 0 0 8.27E+06 5.95E+06 - - - 6.0652 0.9991 221125_WJC_METTL3_EV_vs_WT_F02.20781.20781.2 8.05E-07 13/28 R.ELGIC[160.03]PDDAAVIPIK.N sp|P12273|PIP_HUMAN 1 1609.8385 999 19764 20781 2 1609.844867 805.9265 Prolactin-inducible protein OS=Homo sapiens OX=9606 GN=PIP PE=1 SV=1 4.03 3552.6 - 1.18E+06 - - - 3.9271 - 2.527 0.539 - 512.1 1 2 0 0.0063 15 0 0 0 8.92E+08 0.00E+00 - - - 5.2992 1 221125_WJC_METTL3_EV_vs_WT_F02.20784.20784.3 5.13E-08 23/68 K.IEANAGQLYLTGVVVLHK.D sp|O43395|PRPF3_HUMAN 1 1924.0782 2.76 19765 20784 3 1924.079473 642.3667 U4\U6 small nuclear ribonucleoprotein Prp3 OS=Homo sapiens OX=9606 GN=PRPF3 PE=1 SV=2 6.75 3553 - 5.63E+06 - - - 0.6627 - 4.186 0.666 - 744.3 1 2 0 0.0013 18 0 0 0 6.72E+07 2.43E+07 - - - 9.5301 0.9609 221125_WJC_METTL3_EV_vs_WT_F02.20785.20785.2 0.00375 22-Sep R.NFILDQTNVSAA.A "sp|Q00839|HNRPU_HUMAN,tr|A0A1W2PQL0|A0A1W2PQL0_HUMAN,tr|A0A1W2PPL4|A0A1W2PPL4_HUMAN,tr|A0A1W2PQ74|A0A1W2PQ74_HUMAN,tr|Q5RI18|Q5RI18_HUMAN,tr|A0A1W2PP35|A0A1W2PP35_HUMAN,tr|A0A1W2PPS1|A0A1W2PPS1_HUMAN,tr|A0A1W2PRZ7|A0A1W2PRZ7_HUMAN,tr|A0A1W2PPH7|A0A1W2PPH7_HUMAN,tr|A0A1W2PQD4|A0A1W2PQD4_HUMAN,tr|A0A1W2PP34|A0A1W2PP34_HUMAN,tr|A0A1X7SBS1|A0A1X7SBS1_HUMAN" 12 1291.6408 - 19766 20785 2 1291.641272 646.8277 Heterogeneous nuclear ribonucleoprotein U OS=Homo sapiens OX=9606 GN=HNRNPU PE=1 SV=6 3.8 3553 - 4.45E+06 - - - 0.3414 - 1.465 0.369 - 243.8 1 1 0 0.0004 12 0 0 0 - - - - - 2.771 0.999 221125_WJC_METTL3_EV_vs_WT_F02.20786.20786.2 0.0382 16-Sep K.LNLDSIIGR[166.11].L "sp|P62136|PP1A_HUMAN,tr|E9PMD7|E9PMD7_HUMAN" 2 1009.5796 1.47 19767 20786 2 1009.577835 505.7971 Serine\threonine-protein phosphatase PP1-alpha catalytic subunit OS=Homo sapiens OX=9606 GN=PPP1CA PE=1 SV=1 5.84 3553.2 - 1.41E+06 - - - -1.7136 - 2.027 0.249 - 266.3 1 2 0 -0.0017 9 0 0 0 6.47E+07 4.41E+07 - - - 2.9237 0.9999 221125_WJC_METTL3_EV_vs_WT_F02.20792.20792.2 0.000197 18-Oct R.FEELC[160.03]SDLFR[166.11].S "sp|P48741|HSP77_HUMAN,sp|P0DMV8|HS71A_HUMAN,sp|P0DMV9|HS71B_HUMAN,sp|P17066|HSP76_HUMAN,tr|V9GZ37|V9GZ37_HUMAN,tr|A0A0G2JIW1|A0A0G2JIW1_HUMAN" 6 1324.5997 0.09 19771 20792 2 1324.599463 663.3071 Putative heat shock 70 kDa protein 7 OS=Homo sapiens OX=9606 GN=HSPA7 PE=5 SV=2 4.14 3553.9 - 4.35E+07 - - - -0.185 - 2.29 0.52 - 370 1 2 0 -0.0002 10 0 0 0 1.94E+08 2.17E+09 - - - 5.1944 0.9997 221125_WJC_METTL3_EV_vs_WT_F02.20793.20793.2 0.000178 16-Sep R.FEALNLSFK[136.11].N "sp|P14859|PO2F1_HUMAN,sp|P09086|PO2F2_HUMAN,sp|Q9UKI9|PO2F3_HUMAN,tr|U3KQ96|U3KQ96_HUMAN,tr|U3KQN1|U3KQN1_HUMAN,tr|H0YKT2|H0YKT2_HUMAN,tr|H0YNW1|H0YNW1_HUMAN,tr|B5ME60|B5ME60_HUMAN,tr|H0YLC5|H0YLC5_HUMAN,tr|A0A0C4DG88|A0A0C4DG88_HUMAN,tr|A0A0A0MT46|A0A0A0MT46_HUMAN,tr|H0YLL6|H0YLL6_HUMAN" 12 1075.5793 1.09 19772 20793 2 1075.57713 538.7969 "POU domain, class 2, transcription factor 1 OS=Homo sapiens OX=9606 GN=POU2F1 PE=1 SV=2" 6 3554 - 1.15E+07 - - - -2.0612 - 1.928 0.496 - 185.5 1 2 0 -0.0022 9 0 0 0 1.67E+08 1.54E+08 - - - 4.603 0.9929 221125_WJC_METTL3_EV_vs_WT_F02.20794.20794.2 3.45E-08 14/30 R.IINEPTAAAIAYGLDR[166.11].T "sp|P0DMV8|HS71A_HUMAN,sp|P0DMV9|HS71B_HUMAN,sp|P17066|HSP76_HUMAN,tr|A0A0G2JIW1|A0A0G2JIW1_HUMAN" 4 1696.9024 0.15 19773 20794 2 1697.902335 849.4585 Heat shock 70 kDa protein 1A OS=Homo sapiens OX=9606 GN=HSPA1A PE=1 SV=1 4.37 3554 - 5.57E+06 - - - 589.2973 - 2.875 0.595 - 529.6 1 2 0 1 16 0 0 0 1.75E+09 1.16E+10 - - - 5.718 1 221125_WJC_METTL3_EV_vs_WT_F02.20795.20795.2 1.30E-11 18/28 K.SPFSVAVSPSLDLSK.L "sp|P21333|FLNA_HUMAN,tr|A0A7P0NMY4|A0A7P0NMY4_HUMAN,tr|Q60FE5|Q60FE5_HUMAN" 3 1532.8086 0.84 19774 20795 2 1532.807891 767.4116 Filamin-A OS=Homo sapiens OX=9606 GN=FLNA PE=1 SV=4 5.55 3554.1 - 4.13E+06 - - - -0.4782 - 3.548 0.647 - 1180.1 1 2 0 -0.0007 15 0 0 0 4.10E+07 4.88E+07 - - - 6.933 0.9997 221125_WJC_METTL3_EV_vs_WT_F02.20797.20797.2 2.88E-06 15/26 K.QLAAMLGLTDAQVK.V "sp|Q14774|HLX_HUMAN,tr|F8VWZ5|F8VWZ5_HUMAN" 2 1457.7912 2.86 19776 20797 2 1457.787424 729.9029 H2.0-like homeobox protein OS=Homo sapiens OX=9606 GN=HLX PE=1 SV=3 5.84 3554.2 - 3.22E+06 - - - -2.5902 - 3.073 0.445 - 906.9 1 2 0 -0.0038 14 0 0 0 3.17E+07 1.11E+07 - - - 5.1438 0.9997 221125_WJC_METTL3_EV_vs_WT_F02.20798.20798.2 0.0415 16-Oct K.LNLDSIIGR.L "sp|P62136|PP1A_HUMAN,tr|E9PMD7|E9PMD7_HUMAN" 2 999.5713 1.47 19777 20798 2 999.570619 500.7929 Serine\threonine-protein phosphatase PP1-alpha catalytic subunit OS=Homo sapiens OX=9606 GN=PPP1CA PE=1 SV=1 5.84 3554.3 - 2.96E+06 - - - -0.6763 - 2.14 0.307 - 338.3 1 2 0 -0.0007 9 0 0 0 6.47E+07 4.41E+07 - - - 3.5093 0.9997 221125_WJC_METTL3_EV_vs_WT_F02.20800.20800.2 0.00423 16/26 R.ILAQATSDLVNAIK[136.11].A sp|Q9Y490|TLN1_HUMAN 1 1463.8439 0.99 19779 20800 2 1463.846662 732.9292 Talin-1 OS=Homo sapiens OX=9606 GN=TLN1 PE=1 SV=3 5.84 3554.5 - 2.15E+06 - - - 1.8909 - 2.806 0.416 - 758.5 1 2 0 0.0028 14 0 0 0 1.47E+07 1.48E+07 - - - 4.7019 0.9983 221125_WJC_METTL3_EV_vs_WT_F02.20801.20801.2 0.0133 16-Aug K.FSPTDFLAK[136.11].M "sp|P42704|LPPRC_HUMAN,tr|A0A804HI14|A0A804HI14_HUMAN,tr|A0A804HL40|A0A804HL40_HUMAN,tr|A0A804HKJ0|A0A804HKJ0_HUMAN,tr|A0A804HKR3|A0A804HKR3_HUMAN,tr|A0A0C4DG06|A0A0C4DG06_HUMAN,tr|A0A804HIN4|A0A804HIN4_HUMAN,tr|A0A804HLG8|A0A804HLG8_HUMAN,tr|A0A804HIV5|A0A804HIV5_HUMAN,tr|A0A804HHY9|A0A804HHY9_HUMAN,tr|A0A804HJH8|A0A804HJH8_HUMAN,tr|B8ZZ38|B8ZZ38_HUMAN,tr|A0A804HI40|A0A804HI40_HUMAN,tr|A0A804HJZ1|A0A804HJZ1_HUMAN,tr|C9JCA9|C9JCA9_HUMAN,tr|A0A804HIQ7|A0A804HIQ7_HUMAN,tr|A0A804HK30|A0A804HK30_HUMAN,tr|A0A804HKI2|A0A804HKI2_HUMAN,tr|A0A804HKR5|A0A804HKR5_HUMAN,tr|A0A804HKX0|A0A804HKX0_HUMAN,tr|A0A804HIG4|A0A804HIG4_HUMAN,tr|A0A804HK02|A0A804HK02_HUMAN" 22 1032.5371 0.64 19780 20801 2 1032.536653 517.2758 "Leucine-rich PPR motif-containing protein, mitochondrial OS=Homo sapiens OX=9606 GN=LRPPRC PE=1 SV=3" 5.84 3554.6 - 1.92E+06 - - - -0.4784 - 1.577 0.216 - 179.2 1 2 0 -0.0005 9 0 0 0 1.91E+07 2.99E+07 - - - 1.9541 0.9985 221125_WJC_METTL3_EV_vs_WT_F02.20803.20803.2 3.99E-05 22-Nov R.FYTLIPHDFGMK.K "sp|P09874|PARP1_HUMAN,tr|A0A7I2V3E1|A0A7I2V3E1_HUMAN" 2 1467.7221 6.9 19782 20803 2 1467.71578 734.8683 Poly [ADP-ribose] polymerase 1 OS=Homo sapiens OX=9606 GN=PARP1 PE=1 SV=4 6.74 3554.8 - 1.75E+06 - - - -4.2774 - 2.155 0.5 - 363.2 1 2 0 -0.0063 12 0 0 0 1.21E+07 1.76E+06 - - - 4.7522 1 221125_WJC_METTL3_EV_vs_WT_F02.20805.20805.2 2.92E-09 19/30 R.IINEPTAAAIAYGLDR.T "sp|P0DMV8|HS71A_HUMAN,sp|P0DMV9|HS71B_HUMAN,sp|P17066|HSP76_HUMAN,tr|A0A0G2JIW1|A0A0G2JIW1_HUMAN" 4 1686.8941 0.15 19784 20805 2 1686.892486 844.4543 Heat shock 70 kDa protein 1A OS=Homo sapiens OX=9606 GN=HSPA1A PE=1 SV=1 4.37 3555.1 - 1.01E+06 - - - -0.9479 - 3.331 0.552 - 1009.3 1 2 0 -0.0016 16 0 0 0 1.76E+09 1.17E+10 - - - 6.0759 0.9997 221125_WJC_METTL3_EV_vs_WT_F02.20806.20806.3 0.00359 Nov-40 R.FGPLIVDWPHK.A "sp|Q17RY0|CPEB4_HUMAN,tr|A0A590UJI5|A0A590UJI5_HUMAN,tr|E5RJM0|E5RJM0_HUMAN,tr|E5RFP2|E5RFP2_HUMAN,tr|A0A590UJN2|A0A590UJN2_HUMAN,tr|B7ZLQ8|B7ZLQ8_HUMAN" 6 1307.7026 3.29 19785 20806 3 1307.701125 436.9082 Cytoplasmic polyadenylation element-binding protein 4 OS=Homo sapiens OX=9606 GN=CPEB4 PE=1 SV=1 6.74 3555.2 - 809398 - - - -1.1608 - 2.063 0.332 - 100.6 1 2 0 -0.0015 11 0 0 0 9.41E+06 2.86E+06 - - - 4.2983 0.9999 221125_WJC_METTL3_EV_vs_WT_F02.20810.20810.2 0.000685 14/22 R.SLDLDSIIAEVK.A sp|P04264|K2C1_HUMAN 1 1301.7078 36.83 19787 20810 2 1301.708015 651.8612 "Keratin, type II cytoskeletal 1 OS=Homo sapiens OX=9606 GN=KRT1 PE=1 SV=6" 4.03 3555.7 - 1.39E+07 - - - 0.1283 - 2.723 0.518 - 574.5 1 2 0 0.0002 12 0 0 0 2.68E+08 7.27E+06 - - - 5.5026 0.9863 221125_WJC_METTL3_EV_vs_WT_F02.20811.20811.3 1 Sep-60 R.DGLK[136.11]LMLLLEVISGER[166.11].L "sp|O43707|ACTN4_HUMAN,sp|P12814|ACTN1_HUMAN,tr|A0A804HK61|A0A804HK61_HUMAN,tr|A0A804HIN7|A0A804HIN7_HUMAN,tr|G3V5M4|G3V5M4_HUMAN,tr|A0A804HLF4|A0A804HLF4_HUMAN,tr|A0A804HIY0|A0A804HIY0_HUMAN,tr|A0A7I2V4Y4|A0A7I2V4Y4_HUMAN,tr|A0A804HII9|A0A804HII9_HUMAN,tr|A0A804HJQ9|A0A804HJQ9_HUMAN,tr|F5GXS2|F5GXS2_HUMAN,tr|A0A804HKE2|A0A804HKE2_HUMAN,tr|G3V2N5|G3V2N5_HUMAN,tr|A0A804HLD0|A0A804HLD0_HUMAN,tr|H7C144|H7C144_HUMAN" 15 1803.0295 0.02 19788 20811 3 1803.030806 602.0171 Alpha-actinin-4 OS=Homo sapiens OX=9606 GN=ACTN4 PE=1 SV=2 4.68 3555.7 - 6.67E+06 - - - 0.7371 - 1.644 0.246 - 104.7 1 2 1 0.0013 16 0 0 0 1.41E+06 7.76E+07 - - - 2.5579 1 221125_WJC_METTL3_EV_vs_WT_F02.20813.20813.3 1.11E-07 19/64 K.SPALAFSLAATAQAAPR[166.11].L "sp|Q96PU8|QKI_HUMAN,tr|H0YG47|H0YG47_HUMAN,tr|H0YGD6|H0YGD6_HUMAN" 3 1651.8921 2.25 19790 20813 3 1651.891703 551.638 Protein quaking OS=Homo sapiens OX=9606 GN=QKI PE=1 SV=1 9.47 3555.8 - 4.85E+06 - - - -0.2555 - 3.731 0.553 - 669.5 1 2 0 -0.0004 17 0 0 0 3.33E+08 1.48E+08 - - - 8.0316 1 221125_WJC_METTL3_EV_vs_WT_F02.20814.20814.3 5.61E-10 20/60 R.IINEPTAAAIAYGLDR.T "sp|P0DMV8|HS71A_HUMAN,sp|P0DMV9|HS71B_HUMAN,sp|P17066|HSP76_HUMAN,tr|A0A0G2JIW1|A0A0G2JIW1_HUMAN" 4 1686.8941 0.15 19791 20814 3 1686.892844 563.3053 Heat shock 70 kDa protein 1A OS=Homo sapiens OX=9606 GN=HSPA1A PE=1 SV=1 4.37 3555.9 - 4.34E+06 - - - -0.7357 - 3.628 0.616 - 582 1 2 0 -0.0012 16 0 0 0 1.18E+09 7.59E+09 - - - 8.714 1 221125_WJC_METTL3_EV_vs_WT_F02.20815.20815.2 3.76E-08 16/30 K.GVQGIIVVNTEGIPIK[136.11].S "sp|Q9NP97|DLRB1_HUMAN,tr|B1AKR6|B1AKR6_HUMAN" 2 1643.9702 1.67 19792 20815 2 1643.967411 822.9924 Dynein light chain roadblock-type 1 OS=Homo sapiens OX=9606 GN=DYNLRB1 PE=1 SV=3 6 3555.9 - 3.71E+06 - - - -1.6703 - 3.4 0.502 - 693.5 1 2 0 -0.0027 16 0 0 0 1.03E+08 6.19E+07 - - - 5.7566 0.9998 221125_WJC_METTL3_EV_vs_WT_F02.20818.20818.2 0.000833 22-Dec K.SLSLGEVLDGDR[166.11].M "sp|O15321|TM9S1_HUMAN,tr|E9PJC4|E9PJC4_HUMAN,tr|E9PSI1|E9PSI1_HUMAN,tr|E9PL78|E9PL78_HUMAN,tr|E9PJM1|E9PJM1_HUMAN,tr|E9PS99|E9PS99_HUMAN,tr|E9PQY7|E9PQY7_HUMAN,tr|E9PMQ9|E9PMQ9_HUMAN" 8 1269.644 1.75 19795 20818 2 1269.643106 635.8293 Transmembrane 9 superfamily member 1 OS=Homo sapiens OX=9606 GN=TM9SF1 PE=2 SV=2 4.03 3556.1 - 2.51E+06 - - - -0.7159 - 2.309 0.413 - 468.7 1 2 0 -0.0009 12 0 0 0 3.62E+07 2.08E+07 - - - 4.2929 0.9697 221125_WJC_METTL3_EV_vs_WT_F02.20819.20819.2 3.69E-07 15/32 K.LALLSVTTGGTAEMYTK[136.11].T "sp|P16083|NQO2_HUMAN,tr|Q5TD07|Q5TD07_HUMAN" 2 1762.9266 0.54 19796 20819 2 1762.910381 882.4706 Ribosyldihydronicotinamide dehydrogenase [quinone] OS=Homo sapiens OX=9606 GN=NQO2 PE=1 SV=5 6 3556.2 - 2.05E+06 - - - -9.2216 - 2.851 0.342 - 661.4 1 2 0 -0.0163 17 0 0 0 2.56E+07 4.75E+07 - - - 4.1377 0.9998 221125_WJC_METTL3_EV_vs_WT_F02.20820.20820.3 2.53E-05 19/56 K.WTTLNSLQLHGLQLR[166.11].L sp|Q08J23|NSUN2_HUMAN 1 1788.9874 1.09 19797 20820 3 1788.982477 597.3364 RNA cytosine C(5)-methyltransferase NSUN2 OS=Homo sapiens OX=9606 GN=NSUN2 PE=1 SV=2 9.76 3556.3 - 973282 - - - -2.7641 - 2.807 0.405 - 346 1 2 0 -0.0049 15 0 0 0 4.15E+07 3.79E+07 - - - 5.7472 0.9988 221125_WJC_METTL3_EV_vs_WT_F02.20821.20821.3 0.101 13/40 R.QFLFRPWDVTK.L sp|P22314|UBA1_HUMAN 1 1435.7612 0.57 19798 20821 3 1435.758226 479.5944 Ubiquitin-like modifier-activating enzyme 1 OS=Homo sapiens OX=9606 GN=UBA1 PE=1 SV=3 8.75 3556.5 - 960024 - - - -2.086 - 1.893 0.296 - 217.7 1 2 0 -0.003 11 0 0 0 1.66E+07 2.93E+07 - - - 3.6522 0.9997 221125_WJC_METTL3_EV_vs_WT_F02.20822.20822.3 0.0397 14/40 R.INLWHLEITDR[166.11].S "sp|Q66LE6|2ABD_HUMAN,sp|P63151|2ABA_HUMAN,tr|A0A590UJJ1|A0A590UJJ1_HUMAN,tr|A0A590UJY3|A0A590UJY3_HUMAN" 4 1418.7546 0.46 19799 20822 3 1418.753663 473.9255 Serine\threonine-protein phosphatase 2A 55 kDa regulatory subunit B delta isoform OS=Homo sapiens OX=9606 GN=PPP2R2D PE=1 SV=1 5.32 3556.6 - 876535 - - - -0.6386 - 2.79 0.248 - 452.2 1 2 0 -0.0009 11 0 0 0 8.19E+06 1.80E+07 - - - 4.2195 1 221125_WJC_METTL3_EV_vs_WT_F02.20826.20826.3 8.53E-08 15/60 R.IINEPTAAAIAYGLDR[166.11].T "sp|P0DMV8|HS71A_HUMAN,sp|P0DMV9|HS71B_HUMAN,sp|P17066|HSP76_HUMAN,tr|A0A0G2JIW1|A0A0G2JIW1_HUMAN" 4 1696.9024 0.15 19801 20826 3 1696.901187 566.6414 Heat shock 70 kDa protein 1A OS=Homo sapiens OX=9606 GN=HSPA1A PE=1 SV=1 4.37 3557.1 - 1.23E+08 - - - -0.6883 - 3.339 0.629 - 240.8 1 2 0 -0.0012 16 0 0 0 1.17E+09 7.59E+09 - - - 8.646 0.9999 221125_WJC_METTL3_EV_vs_WT_F02.20827.20827.2 0.000742 18-Sep R.FEELC[160.03]SDLFR.S "sp|P48741|HSP77_HUMAN,sp|P0DMV8|HS71A_HUMAN,sp|P0DMV9|HS71B_HUMAN,sp|P17066|HSP76_HUMAN,tr|V9GZ37|V9GZ37_HUMAN,tr|A0A0G2JIW1|A0A0G2JIW1_HUMAN" 6 1314.5914 0.09 19802 20827 2 1314.591019 658.303 Putative heat shock 70 kDa protein 7 OS=Homo sapiens OX=9606 GN=HSPA7 PE=5 SV=2 4.14 3557.2 - 1.63E+07 - - - -0.3187 - 2.249 0.533 - 346.4 1 2 0 -0.0004 10 0 0 0 1.94E+08 2.17E+09 - - - 5.2399 0.9999 221125_WJC_METTL3_EV_vs_WT_F02.20829.20829.2 2.74E-05 13/22 K.TDPSILGGMIVR[166.11].L sp|P48047|ATPO_HUMAN 1 1267.6834 1.03 19804 20829 2 1267.683102 634.849 "ATP synthase subunit O, mitochondrial OS=Homo sapiens OX=9606 GN=ATP5PO PE=1 SV=1" 5.5 3557.2 - 5.23E+06 - - - -0.2177 - 2.237 0.491 - 348.8 1 2 0 -0.0003 12 0 0 0 2.14E+08 2.09E+08 - - - 4.7859 0.9999 221125_WJC_METTL3_EV_vs_WT_F02.20831.20831.2 4.45E-08 13/22 K.TDPSILGGMIVR.L sp|P48047|ATPO_HUMAN 1 1257.6751 1.03 19806 20831 2 1257.675294 629.8448 "ATP synthase subunit O, mitochondrial OS=Homo sapiens OX=9606 GN=ATP5PO PE=1 SV=1" 5.5 3557.3 - 3.63E+06 - - - 0.1479 - 2.477 0.518 - 546.2 1 2 0 0.0002 12 0 0 0 2.14E+08 2.08E+08 - - - 5.2535 0.8528 221125_WJC_METTL3_EV_vs_WT_F02.20832.20832.2 0.000576 Nov-32 S.SFASSSASDASKPSSPR[166.11].G sp|Q96IF1|AJUBA_HUMAN 1 1677.7834 - 19807 20832 2 1677.788481 839.899 LIM domain-containing protein ajuba OS=Homo sapiens OX=9606 GN=AJUBA PE=1 SV=1 8.46 3557.5 - 2.11E+06 - - - 3.051 - 1.944 0.293 - 206 1 1 0 0.0051 17 0 0 0 - - - - - 2.8378 1 221125_WJC_METTL3_EV_vs_WT_F02.20834.20834.3 3.06E-06 14/40 K.NAVEEYVYDFR[166.11].D "sp|O95757|HS74L_HUMAN,tr|E9PDE8|E9PDE8_HUMAN" 2 1413.644 0.03 19809 20834 3 1413.642923 472.2219 Heat shock 70 kDa protein 4L OS=Homo sapiens OX=9606 GN=HSPA4L PE=1 SV=3 4.14 3557.6 - 1.74E+06 - - - -0.7725 - 2.317 0.552 - 263.9 1 2 0 -0.0011 11 0 0 0 9.91E+05 2.99E+07 - - - 7.081 0.9997 221125_WJC_METTL3_EV_vs_WT_F02.20835.20835.2 7.56E-05 18-Nov K.FFEFGSLDQK[136.11].L "sp|Q8TB72|PUM2_HUMAN,tr|A0A0C4DG68|A0A0C4DG68_HUMAN" 2 1224.5906 1.31 19810 20835 2 1224.59269 613.3026 Pumilio homolog 2 OS=Homo sapiens OX=9606 GN=PUM2 PE=1 SV=2 4.37 3557.8 - 1.51E+06 - - - 1.674 - 1.759 0.536 - 239.5 1 2 0 0.0021 10 0 0 0 2.21E+08 1.68E+08 - - - 4.5756 1 221125_WJC_METTL3_EV_vs_WT_F02.20840.20840.3 2.19E-10 19/64 K.SPALAFSLAATAQAAPR.L "sp|Q96PU8|QKI_HUMAN,tr|H0YG47|H0YG47_HUMAN,tr|H0YGD6|H0YGD6_HUMAN" 3 1641.8839 2.24 19813 20840 3 1641.882741 548.3019 Protein quaking OS=Homo sapiens OX=9606 GN=QKI PE=1 SV=1 9.47 3558.4 - 2.43E+07 - - - -0.6785 - 3.801 0.553 - 595.6 1 2 0 -0.0011 17 0 0 0 3.34E+08 1.49E+08 - - - 8.0784 1 221125_WJC_METTL3_EV_vs_WT_F02.20842.20842.2 0.329 21/32 K.SPALAFSLAATAQAAPR.L "sp|Q96PU8|QKI_HUMAN,tr|H0YG47|H0YG47_HUMAN,tr|H0YGD6|H0YGD6_HUMAN" 3 1641.8839 2 19815 20842 2 1641.882704 821.9492 Protein quaking OS=Homo sapiens OX=9606 GN=QKI PE=1 SV=1 9.47 3558.5 - 1.27E+07 - - - -0.701 - 3.918 0.627 - 1626.6 1 2 0 -0.0012 17 0 0 0 1.98E+08 9.92E+07 - - - 7.029 1 221125_WJC_METTL3_EV_vs_WT_F02.20844.20844.2 5.31E-10 22/32 K.SPALAFSLAATAQAAPR[166.11].L "sp|Q96PU8|QKI_HUMAN,tr|H0YG47|H0YG47_HUMAN,tr|H0YGD6|H0YGD6_HUMAN" 3 1651.8921 2 19817 20844 2 1651.892105 826.9533 Protein quaking OS=Homo sapiens OX=9606 GN=QKI PE=1 SV=1 9.47 3558.6 - 5.24E+06 - - - -0.0121 - 4.215 0.656 - 1913 1 2 0 0 17 0 0 0 1.97E+08 9.82E+07 - - - 7.4232 0.9998 221125_WJC_METTL3_EV_vs_WT_F02.20845.20845.2 7.92E-06 18-Oct K.FFEFGSLDQK.L "sp|Q8TB72|PUM2_HUMAN,tr|A0A0C4DG68|A0A0C4DG68_HUMAN" 2 1216.5764 1.29 19818 20845 2 1216.574293 609.2955 Pumilio homolog 2 OS=Homo sapiens OX=9606 GN=PUM2 PE=1 SV=2 4.37 3558.6 - 4.64E+06 - - - -1.7648 - 1.97 0.556 - 226.8 1 2 0 -0.0021 10 0 0 0 2.22E+08 1.72E+08 - - - 5.0395 0.9997 221125_WJC_METTL3_EV_vs_WT_F02.20846.20846.2 3.57E-05 18-Oct K.FFEFGSLEQK.L "sp|Q14671|PUM1_HUMAN,tr|Q5T1Z8|Q5T1Z8_HUMAN,tr|H0YDK8|H0YDK8_HUMAN,tr|H0YC97|H0YC97_HUMAN,tr|H0YEH2|H0YEH2_HUMAN,tr|Q5T1Z4|Q5T1Z4_HUMAN,tr|H0YDC5|H0YDC5_HUMAN,tr|E9PR38|E9PR38_HUMAN" 8 1230.5921 4.64 19819 20846 2 1230.590859 616.3033 Pumilio homolog 1 OS=Homo sapiens OX=9606 GN=PUM1 PE=1 SV=3 4.53 3558.7 - 3.17E+06 - - - -1.0003 - 1.925 0.418 - 204.5 1 2 0 -0.0012 10 0 0 0 1.98E+08 4.27E+07 - - - 3.9561 1 221125_WJC_METTL3_EV_vs_WT_F02.20849.20849.3 2.72E-09 22/56 K.WTTLNSLQLHGLQLR.L sp|Q08J23|NSUN2_HUMAN 1 1778.9792 1.09 19822 20849 3 1778.980919 594.0003 RNA cytosine C(5)-methyltransferase NSUN2 OS=Homo sapiens OX=9606 GN=NSUN2 PE=1 SV=2 9.76 3559 - 2.21E+06 - - - 0.9933 - 3.733 0.532 - 674.6 1 2 0 0.0018 15 0 0 0 4.15E+07 3.79E+07 - - - 7.9079 0.9998 221125_WJC_METTL3_EV_vs_WT_F02.20850.20850.2 7.27E-05 22-Nov K.MFVGGLSWDTSK[136.11].K "sp|Q99729|ROAA_HUMAN,tr|D6R9P3|D6R9P3_HUMAN,tr|D6RD18|D6RD18_HUMAN,tr|D6RBZ0|D6RBZ0_HUMAN" 4 1334.642 0.26 19823 20850 2 1334.639333 668.3283 Heterogeneous nuclear ribonucleoprotein A\B OS=Homo sapiens OX=9606 GN=HNRNPAB PE=1 SV=2 5.59 3559 - 3.16E+06 - - - -2.0155 - 2.2 0.522 - 281.1 1 2 0 -0.0027 12 0 0 0 1.50E+07 5.84E+07 - - - 4.9702 0.9932 221125_WJC_METTL3_EV_vs_WT_F02.20851.20851.3 0.00248 16/52 R.LHVTALDYLAPYAK.Y "sp|Q9Y221|NIP7_HUMAN,tr|J3QRR4|J3QRR4_HUMAN,tr|J3QLW7|J3QLW7_HUMAN,tr|J3QRD6|J3QRD6_HUMAN" 4 1573.8504 1.03 19824 20851 3 1573.852969 525.6241 60S ribosome subunit biogenesis protein NIP7 homolog OS=Homo sapiens OX=9606 GN=NIP7 PE=1 SV=1 6.74 3559.2 - 2.03E+06 - - - 1.6132 - 2.134 0.157 - 306.5 1 2 0 0.0025 14 0 0 0 2.17E+07 2.11E+07 - - - 2.3041 0.9993 221125_WJC_METTL3_EV_vs_WT_F02.20852.20852.3 0.0806 Dec-36 K.SAEFLLHMLK[136.11].N "sp|P18621|RL17_HUMAN,tr|A0A087WWH0|A0A087WWH0_HUMAN,tr|J3QS96|J3QS96_HUMAN,tr|J3QLC8|J3QLC8_HUMAN,tr|J3QQT2|J3QQT2_HUMAN,tr|A0A087WY81|A0A087WY81_HUMAN,tr|A0A0A0MRF8|A0A0A0MRF8_HUMAN,tr|J3KRB3|J3KRB3_HUMAN,tr|J3KRX5|J3KRX5_HUMAN,tr|A0A087WXM6|A0A087WXM6_HUMAN,tr|A0A0A6YYL6|A0A0A6YYL6_HUMAN" 11 1195.6515 0.87 19825 20852 3 1195.648839 399.5578 60S ribosomal protein L17 OS=Homo sapiens OX=9606 GN=RPL17 PE=1 SV=3 6.47 3559.3 - 1.80E+06 - - - -2.1971 - 2.049 0.311 - 186.1 1 2 0 -0.0026 10 0 0 0 1.08E+08 1.24E+08 - - - 4.1016 0.9997 221125_WJC_METTL3_EV_vs_WT_F02.20853.20853.2 2.33E-06 14/32 K.LALLSVTTGGTAEMYTK.T "sp|P16083|NQO2_HUMAN,tr|Q5TD07|Q5TD07_HUMAN" 2 1754.9124 0.54 19826 20853 2 1754.908018 878.4635 Ribosyldihydronicotinamide dehydrogenase [quinone] OS=Homo sapiens OX=9606 GN=NQO2 PE=1 SV=5 6 3559.4 - 1.70E+06 - - - -2.5186 - 2.79 0.536 - 307.2 1 2 0 -0.0044 17 0 0 0 2.56E+07 4.75E+07 - - - 5.5211 0.9981 221125_WJC_METTL3_EV_vs_WT_F02.20854.20854.3 7.29E-08 18/68 R.INPYMSSPC[160.03]HIEMILTEK[136.11].E "sp|P18621|RL17_HUMAN,tr|J3QLC8|J3QLC8_HUMAN,tr|J3QQT2|J3QQT2_HUMAN,tr|A0A0A0MRF8|A0A0A0MRF8_HUMAN,tr|J3KRX5|J3KRX5_HUMAN,tr|A0A087WXM6|A0A087WXM6_HUMAN,tr|A0A0A6YYL6|A0A0A6YYL6_HUMAN" 7 2170.0352 0.9 19827 20854 3 2171.031416 724.3523 60S ribosomal protein L17 OS=Homo sapiens OX=9606 GN=RPL17 PE=1 SV=3 5.4 3559.5 - 1.58E+06 - - - 459.0695 - 3.318 0.567 - 313.6 1 2 0 0.9962 18 0 0 0 3.46E+07 3.85E+07 - - - 7.5721 0.9996 221125_WJC_METTL3_EV_vs_WT_F02.20855.20855.3 0.000337 14/36 K.SAEFLLHMLK.N "sp|P18621|RL17_HUMAN,tr|A0A087WWH0|A0A087WWH0_HUMAN,tr|J3QS96|J3QS96_HUMAN,tr|J3QLC8|J3QLC8_HUMAN,tr|J3QQT2|J3QQT2_HUMAN,tr|A0A087WY81|A0A087WY81_HUMAN,tr|A0A0A0MRF8|A0A0A0MRF8_HUMAN,tr|J3KRB3|J3KRB3_HUMAN,tr|J3KRX5|J3KRX5_HUMAN,tr|A0A087WXM6|A0A087WXM6_HUMAN,tr|A0A0A6YYL6|A0A0A6YYL6_HUMAN" 11 1187.6373 0.87 19828 20855 3 1187.635551 396.8864 60S ribosomal protein L17 OS=Homo sapiens OX=9606 GN=RPL17 PE=1 SV=3 6.47 3559.6 - 1.24E+06 - - - -1.444 - 2.129 0.3 - 221.3 1 2 0 -0.0017 10 0 0 0 1.08E+08 1.24E+08 - - - 4.0911 0.9964 221125_WJC_METTL3_EV_vs_WT_F02.20861.20861.2 0.00302 22-Nov R.EAPVDVLTQIGR[166.11].S sp|Q9BVC6|TM109_HUMAN 1 1306.712 1.19 19832 20861 2 1306.714246 654.3633 Transmembrane protein 109 OS=Homo sapiens OX=9606 GN=TMEM109 PE=1 SV=1 4.37 3560.3 - 4.74E+06 - - - 1.692 - 1.943 0.143 - 452.9 1 2 0 0.0022 12 0 0 0 1.31E+08 1.10E+08 - - - 1.8442 0.9961 221125_WJC_METTL3_EV_vs_WT_F02.20862.20862.2 0.0704 22-Oct R.NLDLDSIIAEVK.A "sp|P48668|K2C6C_HUMAN,sp|P04259|K2C6B_HUMAN,sp|P13647|K2C5_HUMAN,sp|P35908|K22E_HUMAN,sp|O95678|K2C75_HUMAN,sp|Q5XKE5|K2C79_HUMAN,sp|P02538|K2C6A_HUMAN,tr|H0YI76|H0YI76_HUMAN,tr|H0YIN9|H0YIN9_HUMAN" 9 1328.7187 999 19833 20862 2 1328.719779 665.3666 "Keratin, type II cytoskeletal 6C OS=Homo sapiens OX=9606 GN=KRT6C PE=1 SV=3" 4.03 3560.4 - 1.54E+07 - - - 0.7767 - 1.253 0.242 - 123.9 1 2 0 0.001 12 0 0 0 1.12E+08 0.00E+00 - - - 1.4215 1 221125_WJC_METTL3_EV_vs_WT_F02.20863.20863.2 3.91E-08 14/24 K.GVDLVLNSLAEEK[136.11].L "sp|P49327|FAS_HUMAN,tr|A0A0U1RQF0|A0A0U1RQF0_HUMAN" 2 1393.7544 0.77 19834 20863 2 1393.761882 697.8845 Fatty acid synthase OS=Homo sapiens OX=9606 GN=FASN PE=1 SV=3 4.14 3560.4 - 4.45E+06 - - - 5.3611 - 2.924 0.551 - 743 1 2 0 0.0075 13 0 0 0 3.46E+07 4.46E+07 - - - 5.8621 0.9998 221125_WJC_METTL3_EV_vs_WT_F02.20864.20864.2 0.00336 18-Nov K.AIAINTFLPK.N sp|Q92615|LAR4B_HUMAN 1 1086.6437 1.55 19835 20864 2 1086.643307 544.3291 La-related protein 4B OS=Homo sapiens OX=9606 GN=LARP4B PE=1 SV=3 8.8 3560.5 - 4.19E+06 - - - -0.3902 - 1.975 0.392 - 306 1 2 0 -0.0004 10 0 0 0 1.10E+08 7.11E+07 - - - 3.8359 1 221125_WJC_METTL3_EV_vs_WT_F02.20866.20866.2 9.99E-07 14/22 K.TLYNNQPIDFLK.K "sp|Q13867|BLMH_HUMAN,tr|K7ESE8|K7ESE8_HUMAN,tr|J3KSD8|J3KSD8_HUMAN,tr|K7ES02|K7ES02_HUMAN" 4 1464.7613 999 19837 20866 2 1464.755796 733.3879 Bleomycin hydrolase OS=Homo sapiens OX=9606 GN=BLMH PE=1 SV=1 5.5 3560.7 - 3.97E+06 - - - -3.744 - 2.541 0.593 - 523.7 1 2 0 -0.0055 12 0 0 0 3.75E+07 0.00E+00 - - - 5.8729 0.9996 221125_WJC_METTL3_EV_vs_WT_F02.20868.20868.2 0.299 22-Dec K.SLALEWAC[160.03]SGIR[166.11].L sp|Q9BY49|PECR_HUMAN 1 1371.6844 1.77 19839 20868 2 1371.68352 686.8495 Peroxisomal trans-2-enoyl-CoA reductase OS=Homo sapiens OX=9606 GN=PECR PE=1 SV=2 5.72 3560.8 - 3.10E+06 - - - -0.6714 - 2.512 0.267 - 589.9 1 2 0 -0.0009 12 0 0 0 4.74E+07 2.67E+07 - - - 3.4363 0.9998 221125_WJC_METTL3_EV_vs_WT_F02.20871.20871.2 0.00099 15/26 K.ELLELGSNVVIASR[166.11].K "sp|Q9BY49|PECR_HUMAN,tr|B4DJS2|B4DJS2_HUMAN" 2 1508.8438 1.32 19842 20871 2 1508.841802 755.4292 Peroxisomal trans-2-enoyl-CoA reductase OS=Homo sapiens OX=9606 GN=PECR PE=1 SV=2 4.53 3561.2 - 1.63E+06 - - - -1.3096 - 2.997 0.432 - 746.6 1 2 0 -0.002 14 0 0 0 8.70E+07 6.57E+07 - - - 4.9855 0.9996 221125_WJC_METTL3_EV_vs_WT_F02.20874.20874.2 0.000732 16-Oct K.FSPTDFLAK.M "sp|P42704|LPPRC_HUMAN,tr|A0A804HI14|A0A804HI14_HUMAN,tr|A0A804HL40|A0A804HL40_HUMAN,tr|A0A804HKJ0|A0A804HKJ0_HUMAN,tr|A0A804HKR3|A0A804HKR3_HUMAN,tr|A0A0C4DG06|A0A0C4DG06_HUMAN,tr|A0A804HIN4|A0A804HIN4_HUMAN,tr|A0A804HLG8|A0A804HLG8_HUMAN,tr|A0A804HIV5|A0A804HIV5_HUMAN,tr|A0A804HHY9|A0A804HHY9_HUMAN,tr|A0A804HJH8|A0A804HJH8_HUMAN,tr|B8ZZ38|B8ZZ38_HUMAN,tr|A0A804HI40|A0A804HI40_HUMAN,tr|A0A804HJZ1|A0A804HJZ1_HUMAN,tr|C9JCA9|C9JCA9_HUMAN,tr|A0A804HIQ7|A0A804HIQ7_HUMAN,tr|A0A804HK30|A0A804HK30_HUMAN,tr|A0A804HKI2|A0A804HKI2_HUMAN,tr|A0A804HKR5|A0A804HKR5_HUMAN,tr|A0A804HKX0|A0A804HKX0_HUMAN,tr|A0A804HIG4|A0A804HIG4_HUMAN,tr|A0A804HK02|A0A804HK02_HUMAN" 22 1024.5229 0.61 19844 20874 2 1024.524371 513.2687 "Leucine-rich PPR motif-containing protein, mitochondrial OS=Homo sapiens OX=9606 GN=LRPPRC PE=1 SV=3" 5.84 3561.5 - 1.82E+06 - - - 1.3899 - 1.672 0.436 - 303.4 1 2 0 0.0014 9 0 0 0 1.89E+07 3.08E+07 - - - 3.7479 1 221125_WJC_METTL3_EV_vs_WT_F02.20877.20877.2 8.54E-07 19/30 K.GVQGIIVVNTEGIPIK.S "sp|Q9NP97|DLRB1_HUMAN,tr|B1AKR6|B1AKR6_HUMAN" 2 1635.956 1.67 19846 20877 2 1635.951614 818.9853 Dynein light chain roadblock-type 1 OS=Homo sapiens OX=9606 GN=DYNLRB1 PE=1 SV=3 6 3561.8 - 2.79E+06 - - - -2.6547 - 3.323 0.533 - 994.6 1 2 0 -0.0043 16 0 0 0 1.03E+08 6.19E+07 - - - 5.9288 0.999 221125_WJC_METTL3_EV_vs_WT_F02.20878.20878.2 0.0919 22-Oct R.NILSVVGTDALK.K sp|O43172|PRP4_HUMAN 1 1228.7027 2.52 19847 20878 2 1228.701427 615.3586 U4\U6 small nuclear ribonucleoprotein Prp4 OS=Homo sapiens OX=9606 GN=PRPF4 PE=1 SV=2 5.84 3561.9 - 1.33E+07 - - - -1.0385 - 2.082 0.213 - 217.5 1 2 0 -0.0013 12 0 0 0 3.37E+08 1.34E+08 - - - 2.5433 1 221125_WJC_METTL3_EV_vs_WT_F02.20879.20879.2 4.47E-05 18/32 R.LLLSYGADPTLATYSGR[166.11].T "sp|Q6W2J9|BCOR_HUMAN,tr|H7BZ37|H7BZ37_HUMAN,tr|H7C2V9|H7C2V9_HUMAN,tr|H7C231|H7C231_HUMAN" 4 1806.9391 1.6 19848 20879 2 1806.934859 904.4768 BCL-6 corepressor OS=Homo sapiens OX=9606 GN=BCOR PE=1 SV=1 5.83 3562 - 3.86E+06 - - - -2.3664 - 3.189 0.632 - 693.5 1 2 0 -0.0043 17 0 0 0 8.13E+07 5.06E+07 - - - 6.5588 0.9997 221125_WJC_METTL3_EV_vs_WT_F02.20886.20886.2 0.000142 18-Sep R.NMQDLVEDFK.N "sp|P13647|K2C5_HUMAN,tr|F8W0C6|F8W0C6_HUMAN" 2 1237.5649 999 19853 20886 2 1237.563167 619.7897 "Keratin, type II cytoskeletal 5 OS=Homo sapiens OX=9606 GN=KRT5 PE=1 SV=3" 4.03 3562.8 - 2.27E+07 - - - -1.3914 - 1.914 0.454 - 290.2 1 2 0 -0.0017 10 0 0 0 9.57E+08 0.00E+00 - - - 4.2058 0.9967 221125_WJC_METTL3_EV_vs_WT_F02.20888.20888.2 1.01 16-Nov R.ALDLENIMR[166.11].K "sp|Q8WVD3|RN138_HUMAN,tr|J3QKM8|J3QKM8_HUMAN,tr|J3KSI2|J3KSI2_HUMAN,tr|J3KRU4|J3KRU4_HUMAN" 4 1083.5622 1.36 19855 20888 2 1083.560305 542.7884 E3 ubiquitin-protein ligase RNF138 OS=Homo sapiens OX=9606 GN=RNF138 PE=1 SV=1 4.37 3562.9 - 4.63E+06 - - - -1.7489 - 2.025 0.105 - 578.4 1 2 0 -0.0019 9 0 0 0 1.15E+08 8.50E+07 - - - 1.8572 1 221125_WJC_METTL3_EV_vs_WT_F02.20889.20889.2 3.62E-08 17/26 L.NEPTAAAIAYGLDR[166.11].T "sp|P0DMV8|HS71A_HUMAN,sp|P0DMV9|HS71B_HUMAN,sp|P17066|HSP76_HUMAN,tr|A0A0G2JIW1|A0A0G2JIW1_HUMAN" 4 1470.7342 0.04 19856 20889 2 1470.72994 736.3744 Heat shock 70 kDa protein 1A OS=Homo sapiens OX=9606 GN=HSPA1A PE=1 SV=1 4.37 3563 - 3.26E+06 - - - -2.9149 - 2.877 0.567 - 979 1 1 0 -0.0043 14 0 0 0 1.74E+06 4.11E+07 - - - 5.8794 1 221125_WJC_METTL3_EV_vs_WT_F02.20891.20891.2 1.16E-05 17/28 R.GAVEAELDPVEYTLR[166.11].K "sp|O75817|POP7_HUMAN,tr|C9JYM0|C9JYM0_HUMAN" 2 1670.8391 1.51 19858 20891 2 1670.843532 836.4268 Ribonuclease P protein subunit p20 OS=Homo sapiens OX=9606 GN=POP7 PE=1 SV=2 4 3563.1 - 2.34E+06 - - - 2.6609 - 3.488 0.605 - 728.1 1 2 0 0.0044 15 0 0 0 5.79E+07 3.82E+07 - - - 6.5797 0.8917 221125_WJC_METTL3_EV_vs_WT_F02.20893.20893.2 4.24E-07 13/24 R.DR[166.11]LSASSLTMESF.A "sp|Q00839|HNRPU_HUMAN,tr|A0A1W2PQL0|A0A1W2PQL0_HUMAN,tr|A0A1W2PPL4|A0A1W2PPL4_HUMAN,tr|A0A1W2PQ74|A0A1W2PQ74_HUMAN,tr|Q5RI18|Q5RI18_HUMAN,tr|A0A1W2PP35|A0A1W2PP35_HUMAN,tr|A0A1W2PPS1|A0A1W2PPS1_HUMAN,tr|A0A1W2PPH7|A0A1W2PPH7_HUMAN,tr|A0A1W2PP34|A0A1W2PP34_HUMAN,tr|A0A1W2PRI6|A0A1W2PRI6_HUMAN,tr|A0A1X7SBS1|A0A1X7SBS1_HUMAN,tr|A0A1W2PNG3|A0A1W2PNG3_HUMAN" 12 1452.6794 1.86 19860 20893 2 1452.680602 727.347 Heterogeneous nuclear ribonucleoprotein U OS=Homo sapiens OX=9606 GN=HNRNPU PE=1 SV=6 4.37 3563.4 - 2.09E+06 - - - 0.8171 - 2.419 0.435 - 587 1 1 1 0.0012 13 0 0 0 5.80E+07 3.11E+07 - - - 4.5207 0.9998 221125_WJC_METTL3_EV_vs_WT_F02.20900.20900.2 0.000166 18-Oct K.FAAQELIEVK[136.11].R "sp|Q86U44|MTA70_HUMAN,tr|F5H6D8|F5H6D8_HUMAN,tr|H0YFV6|H0YFV6_HUMAN,tr|B4DTN4|B4DTN4_HUMAN" 4 1154.6427 0.03 19865 20900 2 1154.640659 578.3286 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 4.53 3564.1 - 2.63E+07 - - - -1.746 - 2.042 0.499 - 264.1 1 2 0 -0.002 10 0 0 0 2.84E+07 1.11E+09 - - - 4.7188 0.9998 221125_WJC_METTL3_EV_vs_WT_F02.20902.20902.2 0.0005 26-Dec K.ELLELGSNVVIASR.K "sp|Q9BY49|PECR_HUMAN,tr|B4DJS2|B4DJS2_HUMAN" 2 1498.8355 1.32 19867 20902 2 1498.833098 750.425 Peroxisomal trans-2-enoyl-CoA reductase OS=Homo sapiens OX=9606 GN=PECR PE=1 SV=2 4.53 3564.2 - 6.96E+06 - - - -1.6079 - 2.572 0.506 - 465.6 1 2 0 -0.0024 14 0 0 0 8.70E+07 6.57E+07 - - - 5.1482 0.9999 221125_WJC_METTL3_EV_vs_WT_F02.20903.20903.2 5.69E-07 13/22 K.ELNVMFIETSAK.A sp|P20340|RAB6A_HUMAN 1 1380.6959 1.07 19868 20903 2 1380.695096 691.3552 Ras-related protein Rab-6A OS=Homo sapiens OX=9606 GN=RAB6A PE=1 SV=3 4.53 3564.2 - 5.36E+06 - - - -0.5845 - 2.422 0.524 - 747 1 2 0 -0.0008 12 0 0 0 1.04E+08 9.74E+07 - - - 5.2385 0.9999 221125_WJC_METTL3_EV_vs_WT_F02.20904.20904.2 0.000535 13/18 K.SAEFLLHMLK.N "sp|P18621|RL17_HUMAN,tr|A0A087WWH0|A0A087WWH0_HUMAN,tr|J3QS96|J3QS96_HUMAN,tr|J3QLC8|J3QLC8_HUMAN,tr|J3QQT2|J3QQT2_HUMAN,tr|A0A087WY81|A0A087WY81_HUMAN,tr|A0A0A0MRF8|A0A0A0MRF8_HUMAN,tr|J3KRB3|J3KRB3_HUMAN,tr|J3KRX5|J3KRX5_HUMAN,tr|A0A087WXM6|A0A087WXM6_HUMAN,tr|A0A0A6YYL6|A0A0A6YYL6_HUMAN" 11 1187.6373 1.11 19869 20904 2 1187.635975 594.8259 60S ribosomal protein L17 OS=Homo sapiens OX=9606 GN=RPL17 PE=1 SV=3 6.47 3564.3 - 3.88E+06 - - - -1.087 - 2.568 0.444 - 577.4 1 2 0 -0.0013 10 0 0 0 4.31E+07 3.87E+07 - - - 4.9525 1 221125_WJC_METTL3_EV_vs_WT_F02.20906.20906.2 2.09E-12 18/30 K.FQDGDLTLYQSNTILR.H "sp|P09211|GSTP1_HUMAN,tr|A0A087X2E9|A0A087X2E9_HUMAN,tr|A8MX94|A8MX94_HUMAN" 3 1882.9425 1.8 19871 20906 2 1882.944324 942.4785 Glutathione S-transferase P OS=Homo sapiens OX=9606 GN=GSTP1 PE=1 SV=2 4.21 3564.6 - 1.76E+06 - - - 0.9729 - 3.384 0.698 - 1094.3 1 2 0 0.0018 16 0 0 0 3.72E+07 2.06E+07 - - - 7.193 0.9995 221125_WJC_METTL3_EV_vs_WT_F02.20907.20907.2 2.15E-05 13/28 R.GGVLFIGANESVSLK.L "sp|P34949|MPI_HUMAN,tr|H3BPB8|H3BPB8_HUMAN,tr|F5GX71|F5GX71_HUMAN" 3 1489.814 0.49 19872 20907 2 1489.810492 745.9143 Mannose-6-phosphate isomerase OS=Homo sapiens OX=9606 GN=MPI PE=1 SV=2 6 3564.7 - 1.38E+06 - - - -2.3842 - 2.38 0.426 - 350.7 1 2 0 -0.0036 15 0 0 0 2.82E+07 5.73E+07 - - - 4.3181 1 221125_WJC_METTL3_EV_vs_WT_F02.20908.20908.2 2.26E-10 19/30 K.FQDGDLTLYQSNTILR[166.11].H "sp|P09211|GSTP1_HUMAN,tr|A0A087X2E9|A0A087X2E9_HUMAN,tr|A8MX94|A8MX94_HUMAN" 3 1892.9508 1.8 19873 20908 2 1892.948756 947.4827 Glutathione S-transferase P OS=Homo sapiens OX=9606 GN=GSTP1 PE=1 SV=2 4.21 3564.8 - 1.12E+06 - - - -1.0597 - 3.833 0.695 - 1385.3 1 2 0 -0.002 16 0 0 0 3.72E+07 2.06E+07 - - - 7.4771 0.9939 221125_WJC_METTL3_EV_vs_WT_F02.20909.20909.2 3.46E-06 14/26 K.LLHHLSDLALTLPT.D "sp|Q86U44|MTA70_HUMAN,tr|B4E349|B4E349_HUMAN,tr|F5H6D8|F5H6D8_HUMAN,tr|H0YFV6|H0YFV6_HUMAN,tr|B4DTN4|B4DTN4_HUMAN" 5 1542.877 - 19874 20909 2 1542.875528 772.4458 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 5.97 3564.9 - 1.10E+06 - - - -0.9405 - 2.663 0.548 - 359.2 1 1 0 -0.0014 14 0 0 0 - - - - - 5.546 0.9999 221125_WJC_METTL3_EV_vs_WT_F02.20912.20912.2 1.78E-05 24-Dec K.DFLAGGVAAAISK.T sp|P05141|ADT2_HUMAN 1 1218.6608 1.1 19875 20912 2 1218.66047 610.3377 ADP\ATP translocase 2 OS=Homo sapiens OX=9606 GN=SLC25A5 PE=1 SV=7 5.84 3565.3 - 2.27E+07 - - - -0.302 - 2.496 0.523 - 386.2 1 2 0 -0.0004 13 0 0 0 3.01E+08 2.74E+08 - - - 5.2513 0.9998 221125_WJC_METTL3_EV_vs_WT_F02.20913.20913.2 6.87E-07 22-Dec K.ELNVMFIETSAK[136.11].A sp|P20340|RAB6A_HUMAN 1 1388.7101 1.14 19876 20913 2 1388.708136 695.3623 Ras-related protein Rab-6A OS=Homo sapiens OX=9606 GN=RAB6A PE=1 SV=3 4.53 3565.4 - 6.77E+06 - - - -1.4164 - 2.256 0.524 - 577.2 1 2 0 -0.002 12 0 0 0 1.03E+08 8.99E+07 - - - 5.0513 0.9997 221125_WJC_METTL3_EV_vs_WT_F02.20915.20915.2 2.25E-07 26-Dec R.NVVTIFSAPNYC[160.03]YR[166.11].C "sp|P67775|PP2AA_HUMAN,sp|P62714|PP2AB_HUMAN,tr|H0YC23|H0YC23_HUMAN" 3 1712.822 0.52 19878 20915 2 1712.82499 857.4183 Serine\threonine-protein phosphatase 2A catalytic subunit alpha isoform OS=Homo sapiens OX=9606 GN=PPP2CA PE=1 SV=1 8.2 3565.6 - 3.56E+06 - - - 1.7474 - 2.49 0.414 - 408.8 1 2 0 0.003 14 0 0 0 1.83E+07 3.53E+07 - - - 4.3872 0.9998 221125_WJC_METTL3_EV_vs_WT_F02.20917.20917.2 1.47E-06 13/18 K.SAEFLLHMLK[136.11].N "sp|P18621|RL17_HUMAN,tr|A0A087WWH0|A0A087WWH0_HUMAN,tr|J3QS96|J3QS96_HUMAN,tr|J3QLC8|J3QLC8_HUMAN,tr|J3QQT2|J3QQT2_HUMAN,tr|A0A087WY81|A0A087WY81_HUMAN,tr|A0A0A0MRF8|A0A0A0MRF8_HUMAN,tr|J3KRB3|J3KRB3_HUMAN,tr|J3KRX5|J3KRX5_HUMAN,tr|A0A087WXM6|A0A087WXM6_HUMAN,tr|A0A0A6YYL6|A0A0A6YYL6_HUMAN" 11 1195.6515 1.11 19880 20917 2 1195.652641 598.833 60S ribosomal protein L17 OS=Homo sapiens OX=9606 GN=RPL17 PE=1 SV=3 6.47 3565.7 - 2.82E+06 - - - 0.9827 - 2.628 0.413 - 443.8 1 2 0 0.0012 10 0 0 0 4.31E+07 3.87E+07 - - - 4.7881 0.9998 221125_WJC_METTL3_EV_vs_WT_F02.20920.20920.3 4.39E-05 17/48 K.DFLAGGVAAAISK[136.11].T sp|P05141|ADT2_HUMAN 1 1226.675 1.07 19883 20920 3 1226.671591 409.899 ADP\ATP translocase 2 OS=Homo sapiens OX=9606 GN=SLC25A5 PE=1 SV=7 5.84 3566.1 - 1.64E+06 - - - -2.81 - 2.411 0.421 - 269.8 1 2 0 -0.0034 13 0 0 0 1.99E+07 1.87E+07 - - - 5.6188 0.9999 221125_WJC_METTL3_EV_vs_WT_F02.20922.20922.2 8.69E-06 14/24 R.TPTMAGGLFSIDR[166.11].D "sp|Q10472|GALT1_HUMAN,sp|Q8IUC8|GLT13_HUMAN,tr|K7EJV8|K7EJV8_HUMAN" 3 1374.6841 1.39 19885 20922 2 1374.68483 688.3493 Polypeptide N-acetylgalactosaminyltransferase 1 OS=Homo sapiens OX=9606 GN=GALNT1 PE=1 SV=1 5.5 3566.3 - 1.25E+06 - - - 0.5267 - 2.68 0.506 - 757.4 1 2 0 0.0007 13 0 0 0 2.02E+07 1.45E+07 - - - 5.3082 0.9921 221125_WJC_METTL3_EV_vs_WT_F02.20925.20925.2 1.17E-05 26-Dec L.LTPLNLQIDPSIQR.V "sp|P13647|K2C5_HUMAN,tr|F8W0C6|F8W0C6_HUMAN,tr|F8VU69|F8VU69_HUMAN" 3 1606.9043 999 19886 20925 2 1606.905201 804.4594 "Keratin, type II cytoskeletal 5 OS=Homo sapiens OX=9606 GN=KRT5 PE=1 SV=3" 5.84 3566.7 - 8.35E+06 - - - 0.5881 - 2.107 0.539 - 278 1 1 0 0.0009 14 0 0 0 1.10E+08 0.00E+00 - - - 4.892 1 221125_WJC_METTL3_EV_vs_WT_F02.20927.20927.2 2.44E-09 16/32 R.LLLSYGADPTLATYSGR.T "sp|Q6W2J9|BCOR_HUMAN,tr|H7BZ37|H7BZ37_HUMAN,tr|H7C2V9|H7C2V9_HUMAN,tr|H7C231|H7C231_HUMAN" 4 1796.9309 1.6 19888 20927 2 1796.931767 899.4727 BCL-6 corepressor OS=Homo sapiens OX=9606 GN=BCOR PE=1 SV=1 5.83 3567 - 2.07E+06 - - - 0.502 - 3.007 0.622 - 555.2 1 2 0 0.0009 17 0 0 0 8.13E+07 5.06E+07 - - - 6.3415 1 221125_WJC_METTL3_EV_vs_WT_F02.20928.20928.2 3.26E-07 17/28 K.EFAGEDTSDLFLEER[166.11].E "sp|O14980|XPO1_HUMAN,tr|A0A7I2V488|A0A7I2V488_HUMAN,tr|A0A7I2V461|A0A7I2V461_HUMAN,tr|A0A7I2V2H0|A0A7I2V2H0_HUMAN,tr|A0A7I2V3W6|A0A7I2V3W6_HUMAN,tr|A0A7I2YQX3|A0A7I2YQX3_HUMAN,tr|A0A7I2V2Y6|A0A7I2V2Y6_HUMAN,tr|A0A7I2V6B9|A0A7I2V6B9_HUMAN,tr|A0A7I2V2S3|A0A7I2V2S3_HUMAN" 9 1766.7874 0.36 19889 20928 2 1766.78529 884.401 Exportin-1 OS=Homo sapiens OX=9606 GN=XPO1 PE=1 SV=1 3.77 3567.1 - 1.63E+06 - - - -1.2197 - 3.317 0.644 - 1134.8 1 2 0 -0.0022 15 0 0 0 5.60E+06 1.55E+07 - - - 6.7449 1 221125_WJC_METTL3_EV_vs_WT_F02.20929.20929.3 1.05E-07 14/44 K.VHLVGIDIFTGK.K "sp|P63241|IF5A1_HUMAN,sp|Q9GZV4|IF5A2_HUMAN,sp|Q6IS14|IF5AL_HUMAN,tr|C9J4W5|C9J4W5_HUMAN,tr|I3L397|I3L397_HUMAN,tr|I3L504|I3L504_HUMAN,tr|C9J7B5|C9J7B5_HUMAN,tr|F8WCJ1|F8WCJ1_HUMAN" 8 1297.7394 0.96 19890 20929 3 1297.742462 433.5871 Eukaryotic translation initiation factor 5A-1 OS=Homo sapiens OX=9606 GN=EIF5A PE=1 SV=2 6.71 3567.2 - 1.54E+06 - - - 2.3418 - 2.686 0.552 - 482.8 1 2 0 0.003 12 0 0 0 7.57E+07 7.91E+07 - - - 7.4321 0.9989 221125_WJC_METTL3_EV_vs_WT_F02.20932.20932.2 0.00113 20-Oct K.NFYVEVPELAK.M "sp|Q7L014|DDX46_HUMAN,tr|D6RJA6|D6RJA6_HUMAN,tr|A0A0C4DG89|A0A0C4DG89_HUMAN" 3 1307.6762 0.67 19893 20932 2 1307.679155 654.8454 Probable ATP-dependent RNA helicase DDX46 OS=Homo sapiens OX=9606 GN=DDX46 PE=1 SV=2 4.53 3567.6 - 1.65E+06 - - - 2.2949 - 1.85 0.354 - 244.6 1 2 0 0.003 11 0 0 0 1.72E+07 2.58E+07 - - - 3.3189 0.9999 221125_WJC_METTL3_EV_vs_WT_F02.20934.20934.3 0.00123 16/48 R.SLLINAVEASC[160.03]IR.T "sp|P32322|P5CR1_HUMAN,sp|Q96C36|P5CR2_HUMAN,tr|A0A087WZR9|A0A087WZR9_HUMAN,tr|J3QKT4|J3QKT4_HUMAN,tr|E2QRB3|E2QRB3_HUMAN,tr|A0A087WTV6|A0A087WTV6_HUMAN,tr|J3KR12|J3KR12_HUMAN" 7 1444.7708 0.34 19895 20934 3 1444.766421 482.5975 "Pyrroline-5-carboxylate reductase 1, mitochondrial OS=Homo sapiens OX=9606 GN=PYCR1 PE=1 SV=2" 5.72 3567.9 - 852261 - - - -3.0302 - 3.139 0.438 - 390.8 1 2 0 -0.0044 13 0 0 0 6.05E+06 1.75E+07 - - - 6.5235 0.9999 221125_WJC_METTL3_EV_vs_WT_F02.20938.20938.2 2.42E-06 14/24 K.DFLAGGVAAAISK[136.11].T sp|P05141|ADT2_HUMAN 1 1226.675 1.08 19898 20938 2 1226.675242 614.3448 ADP\ATP translocase 2 OS=Homo sapiens OX=9606 GN=SLC25A5 PE=1 SV=7 5.84 3568.3 - 3.72E+07 - - - 0.1663 - 2.723 0.533 - 487.4 1 2 0 0.0002 13 0 0 0 2.97E+08 2.74E+08 - - - 5.5487 0.9996 221125_WJC_METTL3_EV_vs_WT_F02.20939.20939.2 0.000132 16-Aug R.SPTWFGIPR.L "sp|P78347|GTF2I_HUMAN,tr|A0A494C1K3|A0A494C1K3_HUMAN" 2 1059.5502 1.5 19899 20939 2 1059.549866 530.7824 General transcription factor II-I OS=Homo sapiens OX=9606 GN=GTF2I PE=1 SV=2 9.47 3568.4 - 2.58E+06 - - - -0.2822 - 1.873 0.338 - 325.9 1 2 0 -0.0003 9 0 0 0 6.26E+08 4.17E+08 - - - 3.3529 1 221125_WJC_METTL3_EV_vs_WT_F02.20940.20940.3 3.67E-07 Dec-44 K.VHLVGIDIFTGK[136.11].K "sp|P63241|IF5A1_HUMAN,sp|Q9GZV4|IF5A2_HUMAN,sp|Q6IS14|IF5AL_HUMAN,tr|C9J4W5|C9J4W5_HUMAN,tr|I3L397|I3L397_HUMAN,tr|I3L504|I3L504_HUMAN,tr|C9J7B5|C9J7B5_HUMAN,tr|F8WCJ1|F8WCJ1_HUMAN" 8 1305.7536 0.96 19900 20940 3 1305.753017 436.2585 Eukaryotic translation initiation factor 5A-1 OS=Homo sapiens OX=9606 GN=EIF5A PE=1 SV=2 6.71 3568.5 - 5.14E+06 - - - -0.4641 - 2.67 0.54 - 367.7 1 2 0 -0.0006 12 0 0 0 7.57E+07 7.91E+07 - - - 7.2825 0.9998 221125_WJC_METTL3_EV_vs_WT_F02.20941.20941.3 0.000277 Nov-48 K.DFLAGGVAAAISK.T sp|P05141|ADT2_HUMAN 1 1218.6608 1.07 19901 20941 3 1218.66052 407.2276 ADP\ATP translocase 2 OS=Homo sapiens OX=9606 GN=SLC25A5 PE=1 SV=7 5.84 3568.5 - 3.51E+06 - - - -0.2609 - 2.002 0.372 - 163 1 2 0 -0.0003 13 0 0 0 1.99E+07 1.87E+07 - - - 4.5694 0.9998 221125_WJC_METTL3_EV_vs_WT_F02.20943.20943.2 1.92E-07 22-Dec R.DAAFEALGTALK.V sp|Q14008|CKAP5_HUMAN 1 1205.6292 1.55 19903 20943 2 1205.63014 603.8219 Cytoskeleton-associated protein 5 OS=Homo sapiens OX=9606 GN=CKAP5 PE=1 SV=3 4.37 3568.6 - 2.31E+06 - - - 0.7772 - 2.541 0.428 - 512.2 1 2 0 0.0009 12 0 0 0 2.65E+07 1.71E+07 - - - 4.6556 0.9997 221125_WJC_METTL3_EV_vs_WT_F02.20946.20946.2 0.00045 20-Nov K.VANVSLLALYK[136.11].G sp|P62266|RS23_HUMAN 1 1197.7213 1.03 19906 20946 2 1197.722028 599.8679 40S ribosomal protein S23 OS=Homo sapiens OX=9606 GN=RPS23 PE=1 SV=3 8.56 3568.8 - 1.82E+06 - - - 0.6412 - 1.945 0.38 - 200.4 1 2 0 0.0008 11 0 0 0 1.50E+07 1.46E+07 - - - 3.6471 0.9593 221125_WJC_METTL3_EV_vs_WT_F02.20950.20950.2 1.10E-05 15/34 R.PAISSFSSSGIGFGESLK.A sp|P49790|NU153_HUMAN 1 1769.8836 0.99 19910 20950 2 1769.879383 885.9491 Nuclear pore complex protein Nup153 OS=Homo sapiens OX=9606 GN=NUP153 PE=1 SV=2 6.43 3569.4 - 940175 - - - -2.3713 - 3.175 0.259 - 407.8 1 1 0 -0.0042 18 0 0 0 6.85E+06 6.91E+06 - - - 3.793 1 221125_WJC_METTL3_EV_vs_WT_F02.20951.20951.2 7.61E-09 15/34 R.LEFIVSTGPYPSESAMTK.A "sp|Q08188|TGM3_HUMAN,tr|A0A494C0J7|A0A494C0J7_HUMAN" 2 1955.955 999 19911 20951 2 1955.956201 978.9848 Protein-glutamine gamma-glutamyltransferase E OS=Homo sapiens OX=9606 GN=TGM3 PE=1 SV=4 4.53 3569.5 - 917651 - - - 0.5982 - 2.832 0.658 - 550.5 1 2 0 0.0012 18 0 0 0 8.00E+06 0.00E+00 - - - 6.4599 1 221125_WJC_METTL3_EV_vs_WT_F02.20952.20952.2 2.91E-09 17/26 K.APAEVQITAEQLLR.E "sp|Q9BZJ0|CRNL1_HUMAN,tr|Q5JY65|Q5JY65_HUMAN" 2 1537.8464 999 19912 20952 2 1537.847116 769.9305 Crooked neck-like protein 1 OS=Homo sapiens OX=9606 GN=CRNKL1 PE=1 SV=4 4.53 3569.6 - 588209 - - - 0.461 - 3.53 0.63 - 1430.1 1 2 0 0.0007 14 0 0 0 7.79E+06 0.00E+00 - - - 6.8591 0.9977 221125_WJC_METTL3_EV_vs_WT_F02.20954.20954.3 0.000486 Sep-40 K.FAAQELIEVK[136.11]R[166.11].G "sp|Q86U44|MTA70_HUMAN,tr|F5H6D8|F5H6D8_HUMAN,tr|H0YFV6|H0YFV6_HUMAN,tr|B4DTN4|B4DTN4_HUMAN" 4 1320.7521 21.45 19914 20954 3 1320.750861 441.258 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 6.14 3569.9 - 399849 - - - -0.9048 - 1.976 0.203 - 87.3 1 2 0 -0.0012 11 0 0 0 5.95E+07 2.77E+06 - - - 2.7377 0.9996 221125_WJC_METTL3_EV_vs_WT_F02.20960.20960.2 0.000937 16-Oct R.VSFELFADK.V "sp|P62937|PPIA_HUMAN,tr|C9J5S7|C9J5S7_HUMAN,tr|F8WE65|F8WE65_HUMAN,tr|A0A7I2V5J5|A0A7I2V5J5_HUMAN" 4 1054.5335 1.01 19918 20960 2 1054.534822 528.274 Peptidyl-prolyl cis-trans isomerase A OS=Homo sapiens OX=9606 GN=PPIA PE=1 SV=2 4.37 3570.4 - 3.01E+06 - - - 1.2423 - 1.853 0.381 - 258.4 1 2 0 0.0013 9 0 0 0 6.49E+07 6.42E+07 - - - 3.6391 0.9999 221125_WJC_METTL3_EV_vs_WT_F02.20962.20962.2 0.000202 24-Dec K.DGQILPVPNVVVR[166.11].D sp|Q9P258|RCC2_HUMAN 1 1414.8172 0.32 19920 20962 2 1414.818477 708.4159 Protein RCC2 OS=Homo sapiens OX=9606 GN=RCC2 PE=1 SV=2 5.84 3570.6 - 1.48E+06 - - - 0.9245 - 2.232 0.532 - 384 1 2 0 0.0013 13 0 0 0 4.57E+06 1.42E+07 - - - 5.0306 0.9997 221125_WJC_METTL3_EV_vs_WT_F02.20963.20963.2 0.00578 24-Oct K.GLLPEPNPVQIMK.S "sp|Q9HCJ3|RAVR2_HUMAN,tr|E9PE10|E9PE10_HUMAN" 2 1434.7905 2.98 19921 20963 2 1434.792517 718.4025 Ribonucleoprotein PTB-binding 2 OS=Homo sapiens OX=9606 GN=RAVER2 PE=1 SV=2 6 3570.8 - 1.40E+06 - - - 1.4253 - 2.142 0.465 - 335.3 1 2 0 0.002 13 0 0 0 3.46E+07 1.16E+07 - - - 4.4299 0.9997 221125_WJC_METTL3_EV_vs_WT_F02.20964.20964.2 0.00521 18-Oct K.DIYALISDQK.H "sp|P58107|EPIPL_HUMAN,tr|A0A075B730|A0A075B730_HUMAN" 2 1164.6027 0.42 19922 20964 2 1164.602457 583.3086 Epiplakin OS=Homo sapiens OX=9606 GN=EPPK1 PE=1 SV=3 4.21 3570.9 - 902884 - - - -0.1692 - 1.929 0.355 - 278.1 1 2 0 -0.0002 10 0 0 0 8.55E+06 2.06E+07 - - - 3.4969 0.9999 221125_WJC_METTL3_EV_vs_WT_F02.20966.20966.3 4.99E-05 Sep-40 K.VHFFNSFFYDK[136.11].L "sp|Q9H4L4|SENP3_HUMAN,tr|A0A087X0R7|A0A087X0R7_HUMAN" 2 1457.6859 0.65 19924 20966 3 1457.686992 486.9026 Sentrin-specific protease 3 OS=Homo sapiens OX=9606 GN=SENP3 PE=1 SV=2 6.71 3571.1 - 575295 - - - 0.7237 - 2.104 0.468 - 101.1 1 2 0 0.0011 11 0 0 0 2.37E+06 3.63E+06 - - - 5.8706 0.9979 221125_WJC_METTL3_EV_vs_WT_F02.20967.20967.2 0.000144 24-Sep R.TPVQPNPIVYMMK.A "sp|O96000|NDUBA_HUMAN,tr|H3BPJ9|H3BPJ9_HUMAN,tr|H3BV16|H3BV16_HUMAN" 3 1516.7782 13.4 19925 20967 2 1516.772382 759.3964 NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 10 OS=Homo sapiens OX=9606 GN=NDUFB10 PE=1 SV=3 8.26 3571.3 - 474850 - - - -3.8311 - 1.992 0.4 - 271.1 1 2 0 -0.0058 13 0 0 0 1.01E+07 7.52E+05 - - - 3.7623 0.992 221125_WJC_METTL3_EV_vs_WT_F02.20972.20972.2 0.0163 18-Nov K.IEVIEIMTDR[166.11].G "sp|Q32P51|RA1L2_HUMAN,sp|P09651|ROA1_HUMAN,tr|A0A7I2YQX9|A0A7I2YQX9_HUMAN,tr|F8VZ49|F8VZ49_HUMAN,tr|A0A7I2V3R8|A0A7I2V3R8_HUMAN,tr|F8VTQ5|F8VTQ5_HUMAN,tr|F8W6I7|F8W6I7_HUMAN,tr|H0YH80|H0YH80_HUMAN,tr|A0A7I2V2L6|A0A7I2V2L6_HUMAN,tr|A0A7I2V3W0|A0A7I2V3W0_HUMAN,tr|A0A7I2V5U9|A0A7I2V5U9_HUMAN,tr|A0A2R8Y4L2|A0A2R8Y4L2_HUMAN" 12 1227.6408 1.38 19928 20972 2 1227.633518 614.8277 Heterogeneous nuclear ribonucleoprotein A1-like 2 OS=Homo sapiens OX=9606 GN=HNRNPA1L2 PE=2 SV=2 4.14 3571.8 - 2.86E+07 - - - -5.9675 - 2.391 0.342 - 508.9 1 2 0 -0.0073 10 0 0 0 9.57E+08 6.95E+08 - - - 3.9979 0.9999 221125_WJC_METTL3_EV_vs_WT_F02.20973.20973.2 0.000179 18-Nov R.FEELNADLFR[166.11].G "sp|P54652|HSP72_HUMAN,sp|P11142|HSP7C_HUMAN,tr|E9PNE6|E9PNE6_HUMAN,tr|A8K7Q2|A8K7Q2_HUMAN,tr|E9PKE3|E9PKE3_HUMAN,tr|E9PN89|E9PN89_HUMAN" 6 1262.6171 0.18 19929 20973 2 1262.61715 632.3158 Heat shock-related 70 kDa protein 2 OS=Homo sapiens OX=9606 GN=HSPA2 PE=1 SV=1 4.14 3571.9 - 1.16E+07 - - - 0.0618 - 2.273 0.444 - 447 1 2 0 0.0001 10 0 0 0 3.16E+08 1.80E+09 - - - 4.6123 0.9998 221125_WJC_METTL3_EV_vs_WT_F02.20975.20975.2 0.00182 16-Oct R.VNLFTDFDK[136.11].Y "sp|P55884|EIF3B_HUMAN,tr|C9JZG1|C9JZG1_HUMAN" 2 1105.5535 1.07 19931 20975 2 1105.552737 553.784 Eukaryotic translation initiation factor 3 subunit B OS=Homo sapiens OX=9606 GN=EIF3B PE=1 SV=3 4.21 3572 - 4.27E+06 - - - -0.7137 - 2.185 0.372 - 507.3 1 2 0 -0.0008 9 0 0 0 3.95E+07 3.68E+07 - - - 4.0496 1 221125_WJC_METTL3_EV_vs_WT_F02.20977.20977.2 5.20E-11 19/30 R.YVMGNNPADLLAVDSR.T sp|Q02413|DSG1_HUMAN 1 1733.8407 109.85 19933 20977 2 1733.831762 867.9276 Desmoglein-1 OS=Homo sapiens OX=9606 GN=DSG1 PE=1 SV=2 4.21 3572.1 - 1.93E+06 - - - -5.1377 - 3.426 0.671 - 1137.7 1 2 0 -0.0089 16 0 0 0 7.33E+07 6.67E+05 - - - 7.0216 1 221125_WJC_METTL3_EV_vs_WT_F02.20981.20981.4 4.91E-08 18/66 R.ELLPLIYHHLLR.A "sp|Q13428|TCOF_HUMAN,tr|E7ETY2|E7ETY2_HUMAN,tr|H0Y8Y7|H0Y8Y7_HUMAN,tr|A0A3B3IS06|A0A3B3IS06_HUMAN,tr|A0A2R8Y857|A0A2R8Y857_HUMAN,tr|A0A2R8Y4M7|A0A2R8Y4M7_HUMAN" 6 1515.8926 -1 19937 20981 4 1515.894648 379.9804 Treacle protein OS=Homo sapiens OX=9606 GN=TCOF1 PE=1 SV=3 7.01 3572.7 - 993928 - - - 1.3715 - 3.228 0.526 - 481 1 2 0 0.0021 12 0 0 0 0.00E+00 0.00E+00 - - - 4.2472 1 221125_WJC_METTL3_EV_vs_WT_F02.20982.20982.2 4.26E-06 13/26 R.FISVGYVDDTQFVR[166.11].F "sp|P01889|HLAB_HUMAN,sp|P13747|HLAE_HUMAN,sp|P01893|HLAH_HUMAN,sp|P10321|HLAC_HUMAN,tr|A0A140T921|A0A140T921_HUMAN,tr|A0A140T942|A0A140T942_HUMAN,tr|F8W9Z8|F8W9Z8_HUMAN,tr|A0A140TA05|A0A140TA05_HUMAN,tr|O19617|O19617_HUMAN,tr|A0A140T9E1|A0A140T9E1_HUMAN,tr|F6U0H7|F6U0H7_HUMAN,tr|A0A140T9Z7|A0A140T9Z7_HUMAN,tr|A2AEA2|A2AEA2_HUMAN,tr|A0A140T9H5|A0A140T9H5_HUMAN,tr|Q5QT33|Q5QT33_HUMAN,tr|A0A140T9J9|A0A140T9J9_HUMAN,tr|A0A140T9L3|A0A140T9L3_HUMAN,tr|A0A140T9B3|A0A140T9B3_HUMAN,tr|Q5SS57|Q5SS57_HUMAN,tr|A0A140TA21|A0A140TA21_HUMAN,tr|A0A140T9D4|A0A140T9D4_HUMAN,tr|A0A140T962|A0A140T962_HUMAN,tr|A0A140T9U8|A0A140T9U8_HUMAN,tr|A0A140TA12|A0A140TA12_HUMAN,tr|A0A1W2PR11|A0A1W2PR11_HUMAN" 25 1654.823 1.26 19938 20982 2 1654.827798 828.4188 "HLA class I histocompatibility antigen, B alpha chain OS=Homo sapiens OX=9606 GN=HLA-B PE=1 SV=3" 4.21 3572.8 - 757921 - - - 2.874 - 2.651 0.599 - 560.4 1 2 0 0.0048 14 0 0 0 1.32E+07 1.05E+07 - - - 5.9103 0.9998 221125_WJC_METTL3_EV_vs_WT_F02.20985.20985.3 0.000625 Aug-40 K.VHFFNSFFYDK.L "sp|Q9H4L4|SENP3_HUMAN,tr|A0A087X0R7|A0A087X0R7_HUMAN" 2 1449.6717 0.65 19941 20985 3 1449.672036 484.2312 Sentrin-specific protease 3 OS=Homo sapiens OX=9606 GN=SENP3 PE=1 SV=2 6.71 3573.2 - 497782 - - - 0.2063 - 1.915 0.381 - 74.7 1 2 0 0.0003 11 0 0 0 2.37E+06 3.63E+06 - - - 4.6334 1 221125_WJC_METTL3_EV_vs_WT_F02.20988.20988.3 2.16E-08 15/60 R.IHFPLATYAPVISAEK[136.11].A "sp|Q6PEY2|TBA3E_HUMAN,sp|P0DPH7|TBA3C_HUMAN,sp|Q71U36|TBA1A_HUMAN,sp|P0DPH8|TBA3D_HUMAN,sp|P68366|TBA4A_HUMAN,sp|P68363|TBA1B_HUMAN,sp|Q9BQE3|TBA1C_HUMAN,tr|F8VVB9|F8VVB9_HUMAN,tr|C9JDS9|C9JDS9_HUMAN,tr|A0A1W2PQM2|A0A1W2PQM2_HUMAN,tr|F5H5D3|F5H5D3_HUMAN" 11 1763.9702 0.74 19943 20988 3 1763.969072 588.9973 Tubulin alpha-3E chain OS=Homo sapiens OX=9606 GN=TUBA3E PE=1 SV=2 6.75 3573.5 - 5.87E+06 - - - -0.6151 - 3.018 0.572 - 257 1 2 0 -0.0011 16 0 0 0 1.47E+08 2.00E+08 - - - 7.7512 0.9999 221125_WJC_METTL3_EV_vs_WT_F02.20990.20990.2 0.000267 18-Nov R.FEELNADLFR.G "sp|P54652|HSP72_HUMAN,sp|P11142|HSP7C_HUMAN,tr|E9PNE6|E9PNE6_HUMAN,tr|A8K7Q2|A8K7Q2_HUMAN,tr|E9PKE3|E9PKE3_HUMAN,tr|E9PN89|E9PN89_HUMAN" 6 1252.6088 0.18 19945 20990 2 1252.608098 627.3117 Heat shock-related 70 kDa protein 2 OS=Homo sapiens OX=9606 GN=HSPA2 PE=1 SV=1 4.14 3573.7 - 6.23E+06 - - - -0.562 - 2.267 0.585 - 472.5 1 2 0 -0.0007 10 0 0 0 3.16E+08 1.80E+09 - - - 5.6462 0.9996 221125_WJC_METTL3_EV_vs_WT_F02.20993.20993.2 0.000805 16-Oct K.ASSLISLLK.Q "sp|P78344|IF4G2_HUMAN,tr|E9PKF8|E9PKF8_HUMAN,tr|H0Y3P2|H0Y3P2_HUMAN,tr|D3DQV9|D3DQV9_HUMAN" 4 930.575 2.05 19948 20993 2 930.573622 466.2948 Eukaryotic translation initiation factor 4 gamma 2 OS=Homo sapiens OX=9606 GN=EIF4G2 PE=1 SV=1 8.8 3573.9 - 1.80E+06 - - - -1.4625 - 1.861 0.413 - 283.5 1 2 0 -0.0014 9 0 0 0 8.48E+07 4.13E+07 - - - 3.8879 0.9998 221125_WJC_METTL3_EV_vs_WT_F02.20995.20995.2 0.00611 16-Oct K.ASSLISLLK[136.11].Q "sp|P78344|IF4G2_HUMAN,tr|E9PKF8|E9PKF8_HUMAN,tr|H0Y3P2|H0Y3P2_HUMAN,tr|D3DQV9|D3DQV9_HUMAN" 4 938.5892 2.05 19950 20995 2 938.588627 470.3019 Eukaryotic translation initiation factor 4 gamma 2 OS=Homo sapiens OX=9606 GN=EIF4G2 PE=1 SV=1 8.8 3574.1 - 1.55E+06 - - - -0.5924 - 2.138 0.396 - 323.7 1 2 0 -0.0006 9 0 0 0 8.48E+07 4.13E+07 - - - 4.164 1 221125_WJC_METTL3_EV_vs_WT_F02.20999.20999.4 4.26E-07 16/66 R.ELLPLIYHHLLR[166.11].A "sp|Q13428|TCOF_HUMAN,tr|E7ETY2|E7ETY2_HUMAN,tr|H0Y8Y7|H0Y8Y7_HUMAN,tr|A0A3B3IS06|A0A3B3IS06_HUMAN,tr|A0A2R8Y857|A0A2R8Y857_HUMAN,tr|A0A2R8Y4M7|A0A2R8Y4M7_HUMAN" 6 1525.9008 0.001 19954 20999 4 1525.897727 382.4825 Treacle protein OS=Homo sapiens OX=9606 GN=TCOF1 PE=1 SV=3 7.01 3574.6 - 976278 - - - -2.0395 - 3.112 0.507 - 405 1 2 0 -0.0031 12 0 0 0 0.00E+00 1.60E+07 - - - 4.0677 0.9972 221125_WJC_METTL3_EV_vs_WT_F02.21001.21001.2 3.28E-05 24-Nov K.SGLQGYDMSTFIR.R "sp|Q13492|PICAL_HUMAN,tr|E9PI56|E9PI56_HUMAN,tr|E9PLJ8|E9PLJ8_HUMAN,tr|E9PKP6|E9PKP6_HUMAN" 4 1473.6922 999 19956 21001 2 1473.698974 737.8534 Phosphatidylinositol-binding clathrin assembly protein OS=Homo sapiens OX=9606 GN=PICALM PE=1 SV=2 5.55 3574.9 - 867831 - - - 4.5871 - 2.053 0.442 - 324.2 1 2 0 0.0068 13 0 0 0 8.91E+06 0.00E+00 - - - 4.1496 0.9997 221125_WJC_METTL3_EV_vs_WT_F02.21002.21002.3 5.54E-05 14/48 R.DLELAYQVHGLLK[136.11].T sp|Q96EY7|PTCD3_HUMAN 1 1505.8333 2.02 19957 21002 3 1505.839201 502.9517 "Pentatricopeptide repeat domain-containing protein 3, mitochondrial OS=Homo sapiens OX=9606 GN=PTCD3 PE=1 SV=3" 5.32 3575.1 - 805980 - - - 3.8995 - 2.411 0.48 - 159.4 1 2 0 0.0059 13 0 0 0 1.48E+07 7.35E+06 - - - 6.2759 0.9998 221125_WJC_METTL3_EV_vs_WT_F02.21004.21004.2 9.64E-06 16-Nov K.YAFVNWINK[136.11].A "sp|P13797|PLST_HUMAN,sp|P13796|PLSL_HUMAN,tr|A0A0A0MSQ0|A0A0A0MSQ0_HUMAN,tr|Q5TBN3|Q5TBN3_HUMAN,tr|U3KQI3|U3KQI3_HUMAN" 5 1161.6062 10.37 19959 21004 2 1161.606244 581.8104 Plastin-3 OS=Homo sapiens OX=9606 GN=PLS3 PE=1 SV=4 8.59 3575.3 - 700793 - - - 0.0121 - 1.921 0.466 - 341.4 1 2 0 0 9 0 0 0 2.45E+08 2.36E+07 - - - 4.3716 1 221125_WJC_METTL3_EV_vs_WT_F02.21009.21009.2 0.00865 16/26 R.VDYLVTEEEINLTR[166.11].G "sp|P57105|SYJ2B_HUMAN,tr|A0A087X1F5|A0A087X1F5_HUMAN,tr|A0A087WYV9|A0A087WYV9_HUMAN,tr|A0A087WTA2|A0A087WTA2_HUMAN" 4 1702.8653 1.53 19962 21009 2 1702.864376 852.4399 Synaptojanin-2-binding protein OS=Homo sapiens OX=9606 GN=SYNJ2BP PE=1 SV=2 4 3576 - 2.29E+06 - - - -0.5432 - 3.283 0.548 - 853.7 1 2 0 -0.0009 14 0 0 0 3.96E+07 2.59E+07 - - - 6.0714 0.9998 221125_WJC_METTL3_EV_vs_WT_F02.21011.21011.2 0.013 14/26 K.LSELLPEEVEAEVK[136.11].A "sp|Q9Y2X3|NOP58_HUMAN,tr|H7BZ72|H7BZ72_HUMAN" 2 1591.8436 1.21 19964 21011 2 1591.844723 796.9291 Nucleolar protein 58 OS=Homo sapiens OX=9606 GN=NOP58 PE=1 SV=1 3.98 3576.1 - 4.08E+06 - - - 0.6935 - 2.53 0.427 - 585.2 1 2 0 0.0011 14 0 0 0 4.81E+07 3.97E+07 - - - 4.5238 0.9999 221125_WJC_METTL3_EV_vs_WT_F02.21012.21012.2 6.94E-08 14/26 R.VDYLVTEEEINLTR.G "sp|P57105|SYJ2B_HUMAN,tr|A0A087X1F5|A0A087X1F5_HUMAN,tr|A0A087WYV9|A0A087WYV9_HUMAN,tr|A0A087WTA2|A0A087WTA2_HUMAN" 4 1692.857 1.53 19965 21012 2 1692.856471 847.4358 Synaptojanin-2-binding protein OS=Homo sapiens OX=9606 GN=SYNJ2BP PE=1 SV=2 4 3576.2 - 3.97E+06 - - - -0.3308 - 3.137 0.494 - 558.2 1 2 0 -0.0006 14 0 0 0 3.96E+07 2.59E+07 - - - 5.5585 0.9981 221125_WJC_METTL3_EV_vs_WT_F02.21013.21013.2 0.025 20-Oct K.LPQLPITNFSR[166.11].D "sp|P21333|FLNA_HUMAN,tr|A0A7P0NMY4|A0A7P0NMY4_HUMAN,tr|Q60FE5|Q60FE5_HUMAN,tr|A0A7I2V3E6|A0A7I2V3E6_HUMAN,tr|A0A087WWY3|A0A087WWY3_HUMAN,tr|F8WE98|F8WE98_HUMAN" 6 1294.7273 1.17 19966 21013 2 1294.726529 648.3709 Filamin-A OS=Homo sapiens OX=9606 GN=FLNA PE=1 SV=4 9.75 3576.3 - 2.34E+06 - - - -0.5885 - 1.996 0.129 - 247.5 1 2 0 -0.0008 11 0 0 0 1.69E+07 1.44E+07 - - - 1.8633 1 221125_WJC_METTL3_EV_vs_WT_F02.21014.21014.2 1.24E-09 18/30 K.APVPTGEVYFADSFDR.G "sp|P27824|CALX_HUMAN,tr|A0A7P0T937|A0A7P0T937_HUMAN,tr|A0A7P0T840|A0A7P0T840_HUMAN,tr|A0A7P0Z4H2|A0A7P0Z4H2_HUMAN,tr|A0A7P0TB65|A0A7P0TB65_HUMAN,tr|D6RD16|D6RD16_HUMAN,tr|A0A7P0TAN9|A0A7P0TAN9_HUMAN,tr|A0A7P0TAE9|A0A7P0TAE9_HUMAN,tr|A0A7P0T8N1|A0A7P0T8N1_HUMAN,tr|A0A7P0T8G1|A0A7P0T8G1_HUMAN,tr|A0A7P0Z4D6|A0A7P0Z4D6_HUMAN,tr|A0A7P0Z484|A0A7P0Z484_HUMAN,tr|A0A7P0TAR9|A0A7P0TAR9_HUMAN,tr|A0A7P0T9L0|A0A7P0T9L0_HUMAN,tr|D6RAQ8|D6RAQ8_HUMAN,tr|D6RAU8|D6RAU8_HUMAN" 16 1769.8261 1.37 19967 21014 2 1769.825881 885.9203 Calnexin OS=Homo sapiens OX=9606 GN=CANX PE=1 SV=2 4.03 3576.4 - 2.14E+06 - - - -0.104 - 2.871 0.692 - 969.8 1 2 0 -0.0002 16 0 0 0 3.54E+08 2.58E+08 - - - 6.745 0.9998 221125_WJC_METTL3_EV_vs_WT_F02.21015.21015.2 6.14E-05 20-Dec K.WMIQYNNLNLK.T "sp|P11586|C1TC_HUMAN,tr|F5H2F4|F5H2F4_HUMAN,tr|V9GZ78|V9GZ78_HUMAN,tr|V9GYY3|V9GYY3_HUMAN,tr|A0A494C1T2|A0A494C1T2_HUMAN" 5 1435.7282 2.97 19968 21015 2 1435.72634 718.8714 "C-1-tetrahydrofolate synthase, cytoplasmic OS=Homo sapiens OX=9606 GN=MTHFD1 PE=1 SV=4" 8.59 3576.5 - 2.12E+06 - - - -1.2997 - 2.142 0.427 - 623.5 1 2 0 -0.0019 11 0 0 0 2.75E+07 9.27E+06 - - - 4.2549 0.9983 221125_WJC_METTL3_EV_vs_WT_F02.21017.21017.2 0.0243 20-Nov K.VTGQFPWSSLR[166.11].E sp|Q9Y512|SAM50_HUMAN 1 1286.6647 1.43 19970 21017 2 1286.667845 644.3396 Sorting and assembly machinery component 50 homolog OS=Homo sapiens OX=9606 GN=SAMM50 PE=1 SV=3 9.72 3576.7 - 1.83E+06 - - - 2.4513 - 1.735 0.329 - 357.5 1 2 0 0.0032 11 0 0 0 3.27E+07 2.29E+07 - - - 2.9606 0.9994 221125_WJC_METTL3_EV_vs_WT_F02.21019.21019.3 0.00172 14/44 K.INALMHALTDLR[166.11].K "sp|Q14527|HLTF_HUMAN,tr|H7C5K0|H7C5K0_HUMAN,tr|A0A0C4DGA6|A0A0C4DGA6_HUMAN" 3 1376.7474 1.22 19972 21019 3 1376.741863 459.9231 Helicase-like transcription factor OS=Homo sapiens OX=9606 GN=HLTF PE=1 SV=2 6.74 3576.9 - 1.06E+06 - - - -4.0036 - 2.697 0.367 - 293.8 1 2 0 -0.0055 12 0 0 0 2.50E+07 2.06E+07 - - - 5.3802 1 221125_WJC_METTL3_EV_vs_WT_F02.21020.21020.3 1.83E-05 21/52 R.LLELADIDPTLRPR.Q sp|Q8WVM0|TFB1M_HUMAN 1 1620.9199 0.9 19973 21020 3 1620.919878 541.3139 "Dimethyladenosine transferase 1, mitochondrial OS=Homo sapiens OX=9606 GN=TFB1M PE=1 SV=1" 4.56 3577 - 1.05E+06 - - - -0.0173 - 3.287 0.489 - 474.6 1 2 0 0 14 0 0 0 1.74E+07 1.92E+07 - - - 7.1543 0.9999 221125_WJC_METTL3_EV_vs_WT_F02.21021.21021.3 1.25E-05 Oct-36 K.IEVIEIMTDR.G "sp|Q32P51|RA1L2_HUMAN,sp|P09651|ROA1_HUMAN,tr|A0A7I2YQX9|A0A7I2YQX9_HUMAN,tr|F8VZ49|F8VZ49_HUMAN,tr|A0A7I2V3R8|A0A7I2V3R8_HUMAN,tr|F8VTQ5|F8VTQ5_HUMAN,tr|F8W6I7|F8W6I7_HUMAN,tr|H0YH80|H0YH80_HUMAN,tr|A0A7I2V2L6|A0A7I2V2L6_HUMAN,tr|A0A7I2V3W0|A0A7I2V3W0_HUMAN,tr|A0A7I2V5U9|A0A7I2V5U9_HUMAN,tr|A0A2R8Y4L2|A0A2R8Y4L2_HUMAN" 12 1217.6326 1.49 19974 21021 3 1217.631553 406.8848 Heterogeneous nuclear ribonucleoprotein A1-like 2 OS=Homo sapiens OX=9606 GN=HNRNPA1L2 PE=2 SV=2 4.14 3577.2 - 1.02E+06 - - - -0.8385 - 2.14 0.449 - 161.3 1 2 0 -0.001 10 0 0 0 7.14E+06 4.80E+06 - - - 5.7675 0.9998 221125_WJC_METTL3_EV_vs_WT_F02.21022.21022.3 0.000864 16/44 K.INALMHALTDLR.K "sp|Q14527|HLTF_HUMAN,tr|H7C5K0|H7C5K0_HUMAN,tr|A0A0C4DGA6|A0A0C4DGA6_HUMAN" 3 1366.7391 1.22 19975 21022 3 1366.736481 456.587 Helicase-like transcription factor OS=Homo sapiens OX=9606 GN=HLTF PE=1 SV=2 6.74 3577.3 - 1.02E+06 - - - -1.9199 - 2.801 0.34 - 384.9 1 2 0 -0.0026 12 0 0 0 2.50E+07 2.06E+07 - - - 5.1849 0.9999 221125_WJC_METTL3_EV_vs_WT_F02.21023.21023.3 4.41E-05 Oct-36 K.IEVIEIMTDR[166.11].G "sp|Q32P51|RA1L2_HUMAN,sp|P09651|ROA1_HUMAN,tr|A0A7I2YQX9|A0A7I2YQX9_HUMAN,tr|F8VZ49|F8VZ49_HUMAN,tr|A0A7I2V3R8|A0A7I2V3R8_HUMAN,tr|F8VTQ5|F8VTQ5_HUMAN,tr|F8W6I7|F8W6I7_HUMAN,tr|H0YH80|H0YH80_HUMAN,tr|A0A7I2V2L6|A0A7I2V2L6_HUMAN,tr|A0A7I2V3W0|A0A7I2V3W0_HUMAN,tr|A0A7I2V5U9|A0A7I2V5U9_HUMAN,tr|A0A2R8Y4L2|A0A2R8Y4L2_HUMAN" 12 1227.6408 1.49 19976 21023 3 1227.640121 410.2209 Heterogeneous nuclear ribonucleoprotein A1-like 2 OS=Homo sapiens OX=9606 GN=HNRNPA1L2 PE=2 SV=2 4.14 3577.4 - 909317 - - - -0.5889 - 2.146 0.405 - 147.7 1 2 0 -0.0007 10 0 0 0 7.14E+06 4.80E+06 - - - 5.2852 0.9999 221125_WJC_METTL3_EV_vs_WT_F02.21024.21024.2 0.000454 16/26 K.IGEAEAAVIEAMGK[136.11].A "sp|Q14254|FLOT2_HUMAN,tr|E7EMK3|E7EMK3_HUMAN,tr|J3QLD9|J3QLD9_HUMAN" 3 1395.7159 2.3 19977 21024 2 1395.715664 698.8652 Flotillin-2 OS=Homo sapiens OX=9606 GN=FLOT2 PE=1 SV=2 4.25 3577.5 - 849284 - - - -0.1806 - 3.244 0.422 - 1052.9 1 2 0 -0.0003 14 0 0 0 3.17E+07 1.38E+07 - - - 5.111 1 221125_WJC_METTL3_EV_vs_WT_F02.21026.21026.3 4.17E-07 18/60 R.IHFPLATYAPVISAEK.A "sp|Q6PEY2|TBA3E_HUMAN,sp|P0DPH7|TBA3C_HUMAN,sp|Q71U36|TBA1A_HUMAN,sp|P0DPH8|TBA3D_HUMAN,sp|P68366|TBA4A_HUMAN,sp|P68363|TBA1B_HUMAN,sp|Q9BQE3|TBA1C_HUMAN,tr|F8VVB9|F8VVB9_HUMAN,tr|C9JDS9|C9JDS9_HUMAN,tr|A0A1W2PQM2|A0A1W2PQM2_HUMAN,tr|F5H5D3|F5H5D3_HUMAN" 11 1755.956 1.18 19978 21026 3 1755.952526 586.3259 Tubulin alpha-3E chain OS=Homo sapiens OX=9606 GN=TUBA3E PE=1 SV=2 6.75 3577.7 - 4.16E+06 - - - -1.9539 - 3.136 0.476 - 330.9 1 2 0 -0.0034 16 0 0 0 4.98E+07 4.22E+07 - - - 6.7786 1 221125_WJC_METTL3_EV_vs_WT_F02.21028.21028.2 6.11E-09 13/30 K.APVPTGEVYFADSFDR[166.11].G "sp|P27824|CALX_HUMAN,tr|A0A7P0T937|A0A7P0T937_HUMAN,tr|A0A7P0T840|A0A7P0T840_HUMAN,tr|A0A7P0Z4H2|A0A7P0Z4H2_HUMAN,tr|A0A7P0TB65|A0A7P0TB65_HUMAN,tr|D6RD16|D6RD16_HUMAN,tr|A0A7P0TAN9|A0A7P0TAN9_HUMAN,tr|A0A7P0TAE9|A0A7P0TAE9_HUMAN,tr|A0A7P0T8N1|A0A7P0T8N1_HUMAN,tr|A0A7P0T8G1|A0A7P0T8G1_HUMAN,tr|A0A7P0Z4D6|A0A7P0Z4D6_HUMAN,tr|A0A7P0Z484|A0A7P0Z484_HUMAN,tr|A0A7P0TAR9|A0A7P0TAR9_HUMAN,tr|A0A7P0T9L0|A0A7P0T9L0_HUMAN,tr|D6RAQ8|D6RAQ8_HUMAN,tr|D6RAU8|D6RAU8_HUMAN" 16 1779.8343 1.37 19979 21028 2 1779.832281 890.9244 Calnexin OS=Homo sapiens OX=9606 GN=CANX PE=1 SV=2 4.03 3577.9 - 6.00E+06 - - - -1.154 - 2.658 0.717 - 467.6 1 2 0 -0.0021 16 0 0 0 3.54E+08 2.58E+08 - - - 6.7395 1 221125_WJC_METTL3_EV_vs_WT_F02.21029.21029.2 6.38E-08 13/20 K.C[160.03]DTYQLIMEVR.D sp|Q08554|DSC1_HUMAN 1 1426.6585 255.57 19980 21029 2 1426.656761 714.3365 Desmocollin-1 OS=Homo sapiens OX=9606 GN=DSC1 PE=1 SV=2 4.37 3578 - 4.63E+06 - - - -1.1993 - 2.648 0.636 - 795.3 1 2 0 -0.0017 11 0 0 0 1.64E+08 6.44E+05 - - - 6.3723 0.9999 221125_WJC_METTL3_EV_vs_WT_F02.21031.21031.3 0.00359 Nov-36 R.DFLLK[136.11]PELLR[166.11].A "sp|Q13838|DX39B_HUMAN,sp|O00148|DX39A_HUMAN,tr|K7EL56|K7EL56_HUMAN,tr|K7EPJ3|K7EPJ3_HUMAN,tr|F6U6E2|F6U6E2_HUMAN,tr|F6TRA5|F6TRA5_HUMAN,tr|A0A0G2JHN7|A0A0G2JHN7_HUMAN,tr|F6S2B7|F6S2B7_HUMAN,tr|F6WLT2|F6WLT2_HUMAN,tr|Q5STU3|Q5STU3_HUMAN,tr|F6R6M7|F6R6M7_HUMAN,tr|F6QYI9|F6QYI9_HUMAN,tr|K7ENP6|K7ENP6_HUMAN,tr|A0A0G2JJL7|A0A0G2JJL7_HUMAN,tr|K7EIL8|K7EIL8_HUMAN,tr|K7EQN7|K7EQN7_HUMAN,tr|K7EN69|K7EN69_HUMAN,tr|F6S4E6|F6S4E6_HUMAN,tr|A0A0A0MT12|A0A0A0MT12_HUMAN,tr|F6SXL5|F6SXL5_HUMAN" 20 1260.7561 0.83 19982 21031 3 1260.75502 421.2593 Spliceosome RNA helicase DDX39B OS=Homo sapiens OX=9606 GN=DDX39B PE=1 SV=1 6.07 3578.1 - 3.97E+06 - - - -0.84 - 2.039 0.431 - 147.3 1 2 0 -0.0011 10 0 0 0 7.58E+07 9.12E+07 - - - 5.4256 0.9999 221125_WJC_METTL3_EV_vs_WT_F02.21032.21032.3 1.02E-08 17/60 K.LYVPVKEYPDFNFVGR.L "sp|Q96PU8|QKI_HUMAN,tr|F5H5U6|F5H5U6_HUMAN,tr|F5GYM3|F5GYM3_HUMAN,tr|F5GXS8|F5GXS8_HUMAN,tr|F5H8C8|F5H8C8_HUMAN" 5 1941.9989 1.72 19983 21032 3 1941.999897 648.3402 Protein quaking OS=Homo sapiens OX=9606 GN=QKI PE=1 SV=1 6.07 3578.1 - 3.67E+06 - - - 0.5211 - 2.93 0.58 - 318.7 1 2 1 0.001 16 0 0 0 2.17E+08 1.26E+08 - - - 7.7645 0.9999 221125_WJC_METTL3_EV_vs_WT_F02.21034.21034.2 1.33E-05 20-Nov R.DLSSVQTLLTK.Q "sp|Q13813|SPTN1_HUMAN,tr|A0A0D9SF54|A0A0D9SF54_HUMAN,tr|A0A0D9SGF6|A0A0D9SGF6_HUMAN" 3 1203.6711 0.63 19985 21034 2 1203.671193 602.8428 "Spectrin alpha chain, non-erythrocytic 1 OS=Homo sapiens OX=9606 GN=SPTAN1 PE=1 SV=3" 5.84 3578.3 - 2.87E+06 - - - 0.1038 - 2.355 0.526 - 304.9 1 2 0 0.0001 11 0 0 0 4.27E+07 6.76E+07 - - - 5.2431 0.9998 221125_WJC_METTL3_EV_vs_WT_F02.21036.21036.3 0.00178 13/52 R.LLELADIDPTLR[166.11]PR[166.11].Q sp|Q8WVM0|TFB1M_HUMAN 1 1640.9364 1.31 19987 21036 3 1640.935388 547.9861 "Dimethyladenosine transferase 1, mitochondrial OS=Homo sapiens OX=9606 GN=TFB1M PE=1 SV=1" 4.56 3578.4 - 2.52E+06 - - - -0.6448 - 2.294 0.35 - 172 1 2 0 -0.0011 14 0 0 0 2.57E+07 1.96E+07 - - - 4.6484 1 221125_WJC_METTL3_EV_vs_WT_F02.21037.21037.3 1.31E-05 Dec-36 R.DFLLKPELLR.A "sp|Q13838|DX39B_HUMAN,sp|O00148|DX39A_HUMAN,tr|K7EL56|K7EL56_HUMAN,tr|K7EPJ3|K7EPJ3_HUMAN,tr|F6U6E2|F6U6E2_HUMAN,tr|F6TRA5|F6TRA5_HUMAN,tr|A0A0G2JHN7|A0A0G2JHN7_HUMAN,tr|F6S2B7|F6S2B7_HUMAN,tr|F6WLT2|F6WLT2_HUMAN,tr|Q5STU3|Q5STU3_HUMAN,tr|F6R6M7|F6R6M7_HUMAN,tr|F6QYI9|F6QYI9_HUMAN,tr|K7ENP6|K7ENP6_HUMAN,tr|A0A0G2JJL7|A0A0G2JJL7_HUMAN,tr|K7EIL8|K7EIL8_HUMAN,tr|K7EQN7|K7EQN7_HUMAN,tr|K7EN69|K7EN69_HUMAN,tr|F6S4E6|F6S4E6_HUMAN,tr|A0A0A0MT12|A0A0A0MT12_HUMAN,tr|F6SXL5|F6SXL5_HUMAN" 20 1242.7336 0.83 19988 21037 3 1242.73426 415.2518 Spliceosome RNA helicase DDX39B OS=Homo sapiens OX=9606 GN=DDX39B PE=1 SV=1 6.07 3578.4 - 1.94E+06 - - - 0.5238 - 2.551 0.426 - 194.1 1 2 0 0.0007 10 0 0 0 7.54E+07 9.11E+07 - - - 6.0242 1 221125_WJC_METTL3_EV_vs_WT_F02.21040.21040.3 5.00E-05 14/52 R.VDYLVTEEEINLTR.G "sp|P57105|SYJ2B_HUMAN,tr|A0A087X1F5|A0A087X1F5_HUMAN,tr|A0A087WYV9|A0A087WYV9_HUMAN,tr|A0A087WTA2|A0A087WTA2_HUMAN" 4 1692.857 1.84 19991 21040 3 1692.854693 565.293 Synaptojanin-2-binding protein OS=Homo sapiens OX=9606 GN=SYNJ2BP PE=1 SV=2 4 3578.7 - 1.71E+06 - - - -1.3811 - 2.629 0.479 - 294.8 1 2 0 -0.0023 14 0 0 0 8.92E+06 4.84E+06 - - - 6.4485 0.9999 221125_WJC_METTL3_EV_vs_WT_F02.21041.21041.3 0.000397 19/48 R.IDILDSALLR[166.11]PGR[166.11].L sp|P62195|PRS8_HUMAN 1 1457.8469 0.77 19992 21041 3 1457.843462 486.9562 26S proteasome regulatory subunit 8 OS=Homo sapiens OX=9606 GN=PSMC5 PE=1 SV=1 5.96 3578.9 - 1.70E+06 - - - -2.3603 - 2.79 0.389 - 575.6 1 2 0 -0.0034 13 0 0 0 3.54E+07 4.60E+07 - - - 5.6579 0.9999 221125_WJC_METTL3_EV_vs_WT_F02.21046.21046.2 1.98E-08 Nov-32 K.VPFC[160.03]PMVGSEVYSTEIK[136.11].K "sp|Q9Y265|RUVB1_HUMAN,tr|E7ETR0|E7ETR0_HUMAN" 2 1949.9358 0.68 19997 21046 2 1949.938956 975.9752 RuvB-like 1 OS=Homo sapiens OX=9606 GN=RUVBL1 PE=1 SV=1 4.53 3579.5 - 692232 - - - 1.6072 - 2.332 0.62 - 111.1 1 2 0 0.0031 17 0 0 0 3.64E+06 5.34E+06 - - - 5.7011 0.7816 221125_WJC_METTL3_EV_vs_WT_F02.21047.21047.2 0.0931 26-Sep A.DGTLITC[160.03]VDSGILR[166.11].V "sp|Q6RFH5|WDR74_HUMAN,tr|E9PS41|E9PS41_HUMAN" 2 1528.7795 0.35 19998 21047 2 1528.784443 765.397 WD repeat-containing protein 74 OS=Homo sapiens OX=9606 GN=WDR74 PE=1 SV=1 4.21 3579.7 - 583044 - - - 3.2575 - 1.699 0.292 - 220.7 1 1 0 0.005 14 0 0 0 3.98E+06 1.13E+07 - - - 2.5263 1 221125_WJC_METTL3_EV_vs_WT_F02.21050.21050.2 2.73E-08 26-Dec R.FGFPEGSVELYAEK.V "sp|P23396|RS3_HUMAN,tr|F2Z2S8|F2Z2S8_HUMAN,tr|H0YCJ7|H0YCJ7_HUMAN,tr|E9PPU1|E9PPU1_HUMAN,tr|H0YF32|H0YF32_HUMAN" 5 1571.7508 0.71 19999 21050 2 1571.751301 786.8827 40S ribosomal protein S3 OS=Homo sapiens OX=9606 GN=RPS3 PE=1 SV=2 4.25 3580 - 3.27E+07 - - - 0.3347 - 2.637 0.606 - 303.7 1 2 0 0.0005 14 0 0 0 5.80E+08 8.18E+08 - - - 5.95 0.9999 221125_WJC_METTL3_EV_vs_WT_F02.21051.21051.3 1.85E-08 16/60 K.LYVPVK[136.11]EYPDFNFVGR[166.11].L "sp|Q96PU8|QKI_HUMAN,tr|F5H5U6|F5H5U6_HUMAN,tr|F5GYM3|F5GYM3_HUMAN,tr|F5GXS8|F5GXS8_HUMAN,tr|F5H8C8|F5H8C8_HUMAN" 5 1960.0214 1.76 20000 21051 3 1960.02159 654.3477 Protein quaking OS=Homo sapiens OX=9606 GN=QKI PE=1 SV=1 6.07 3580.1 - 1.60E+07 - - - 0.1199 - 2.997 0.589 - 288.5 1 2 1 0.0002 16 0 0 0 2.35E+08 1.34E+08 - - - 7.923 1 221125_WJC_METTL3_EV_vs_WT_F02.21052.21052.3 1.57E-07 14/60 K.APVPTGEVYFADSFDR.G "sp|P27824|CALX_HUMAN,tr|A0A7P0T937|A0A7P0T937_HUMAN,tr|A0A7P0T840|A0A7P0T840_HUMAN,tr|A0A7P0Z4H2|A0A7P0Z4H2_HUMAN,tr|A0A7P0TB65|A0A7P0TB65_HUMAN,tr|D6RD16|D6RD16_HUMAN,tr|A0A7P0TAN9|A0A7P0TAN9_HUMAN,tr|A0A7P0TAE9|A0A7P0TAE9_HUMAN,tr|A0A7P0T8N1|A0A7P0T8N1_HUMAN,tr|A0A7P0T8G1|A0A7P0T8G1_HUMAN,tr|A0A7P0Z4D6|A0A7P0Z4D6_HUMAN,tr|A0A7P0Z484|A0A7P0Z484_HUMAN,tr|A0A7P0TAR9|A0A7P0TAR9_HUMAN,tr|A0A7P0T9L0|A0A7P0T9L0_HUMAN,tr|D6RAQ8|D6RAQ8_HUMAN,tr|D6RAU8|D6RAU8_HUMAN" 16 1769.8261 1.31 20001 21052 3 1769.827623 590.9493 Calnexin OS=Homo sapiens OX=9606 GN=CANX PE=1 SV=2 4.03 3580.1 - 7.70E+06 - - - 0.8803 - 2.42 0.611 - 236.6 1 2 0 0.0016 16 0 0 0 7.30E+07 5.57E+07 - - - 7.6192 0.9997 221125_WJC_METTL3_EV_vs_WT_F02.21053.21053.2 0.000159 16-Oct K.MC[160.03]LFAGFQR[166.11].K "sp|Q00839|HNRPU_HUMAN,tr|A0A1W2PQL0|A0A1W2PQL0_HUMAN,tr|A0A1W2PPL4|A0A1W2PPL4_HUMAN,tr|A0A1W2PQ74|A0A1W2PQ74_HUMAN,tr|Q5RI18|Q5RI18_HUMAN,tr|A0A1W2PP35|A0A1W2PP35_HUMAN,tr|A0A1W2PPS1|A0A1W2PPS1_HUMAN,tr|A0A1W2PRZ7|A0A1W2PRZ7_HUMAN,tr|A0A1W2PPH7|A0A1W2PPH7_HUMAN,tr|A0A1W2PQD4|A0A1W2PQD4_HUMAN,tr|A0A1W2PP34|A0A1W2PP34_HUMAN,tr|A0A1X7SBS1|A0A1X7SBS1_HUMAN" 12 1138.5291 0.9 20002 21053 2 1138.529835 570.2718 Heterogeneous nuclear ribonucleoprotein U OS=Homo sapiens OX=9606 GN=HNRNPU PE=1 SV=6 8 3580.2 - 6.99E+06 - - - 0.6227 - 2.004 0.354 - 563.9 1 2 0 0.0007 9 0 0 0 6.29E+08 7.01E+08 - - - 3.6665 0.9995 221125_WJC_METTL3_EV_vs_WT_F02.21054.21054.2 0.00714 18-Aug R.NIQGLFAPLK.L "sp|Q9Y244|POMP_HUMAN,tr|A0A1W2PS02|A0A1W2PS02_HUMAN" 2 1099.639 1.63 20003 21054 2 1099.639435 550.8268 Proteasome maturation protein OS=Homo sapiens OX=9606 GN=POMP PE=1 SV=1 8.75 3580.2 - 5.94E+06 - - - 0.4138 - 1.598 0.381 - 168.8 1 2 0 0.0005 10 0 0 0 1.41E+08 8.68E+07 - - - 3.1634 1 221125_WJC_METTL3_EV_vs_WT_F02.21055.21055.3 2.75E-05 Dec-60 K.APVPTGEVYFADSFDR[166.11].G "sp|P27824|CALX_HUMAN,tr|A0A7P0T937|A0A7P0T937_HUMAN,tr|A0A7P0T840|A0A7P0T840_HUMAN,tr|A0A7P0Z4H2|A0A7P0Z4H2_HUMAN,tr|A0A7P0TB65|A0A7P0TB65_HUMAN,tr|D6RD16|D6RD16_HUMAN,tr|A0A7P0TAN9|A0A7P0TAN9_HUMAN,tr|A0A7P0TAE9|A0A7P0TAE9_HUMAN,tr|A0A7P0T8N1|A0A7P0T8N1_HUMAN,tr|A0A7P0T8G1|A0A7P0T8G1_HUMAN,tr|A0A7P0Z4D6|A0A7P0Z4D6_HUMAN,tr|A0A7P0Z484|A0A7P0Z484_HUMAN,tr|A0A7P0TAR9|A0A7P0TAR9_HUMAN,tr|A0A7P0T9L0|A0A7P0T9L0_HUMAN,tr|D6RAQ8|D6RAQ8_HUMAN,tr|D6RAU8|D6RAU8_HUMAN" 16 1779.8343 1.31 20004 21055 3 1779.833957 594.2854 Calnexin OS=Homo sapiens OX=9606 GN=CANX PE=1 SV=2 4.03 3580.3 - 5.54E+06 - - - -0.2124 - 2.297 0.525 - 152.9 1 2 0 -0.0004 16 0 0 0 7.30E+07 5.57E+07 - - - 6.5269 0.9999 221125_WJC_METTL3_EV_vs_WT_F02.21056.21056.2 1.82E-05 20-Nov R.DLSSVQTLLTK[136.11].Q "sp|Q13813|SPTN1_HUMAN,tr|A0A0D9SF54|A0A0D9SF54_HUMAN,tr|A0A0D9SGF6|A0A0D9SGF6_HUMAN" 3 1211.6853 0.77 20005 21056 2 1211.686527 606.8499 "Spectrin alpha chain, non-erythrocytic 1 OS=Homo sapiens OX=9606 GN=SPTAN1 PE=1 SV=3" 5.84 3580.3 - 5.38E+06 - - - 1.039 - 2.339 0.511 - 292.9 1 2 0 0.0013 11 0 0 0 4.27E+07 5.52E+07 - - - 5.1136 1 221125_WJC_METTL3_EV_vs_WT_F02.21057.21057.2 9.47E-07 15/22 R.LDIDPETITWQR.V "sp|P11586|C1TC_HUMAN,tr|F5H2F4|F5H2F4_HUMAN,tr|V9GZ78|V9GZ78_HUMAN,tr|V9GYY3|V9GYY3_HUMAN,tr|A0A494C1T2|A0A494C1T2_HUMAN" 5 1485.7464 1.7 20006 21057 2 1485.744699 743.8805 "C-1-tetrahydrofolate synthase, cytoplasmic OS=Homo sapiens OX=9606 GN=MTHFD1 PE=1 SV=4" 4.03 3580.4 - 4.09E+06 - - - -1.1166 - 2.931 0.53 - 751.6 1 2 0 -0.0017 12 0 0 0 1.02E+08 5.98E+07 - - - 5.7845 0.9999 221125_WJC_METTL3_EV_vs_WT_F02.21058.21058.2 0.000617 18-Nov R.NIQGLFAPLK[136.11].L "sp|Q9Y244|POMP_HUMAN,tr|A0A1W2PS02|A0A1W2PS02_HUMAN" 2 1107.6532 1.63 20007 21058 2 1107.653065 554.8339 Proteasome maturation protein OS=Homo sapiens OX=9606 GN=POMP PE=1 SV=1 8.75 3580.4 - 3.68E+06 - - - -0.1038 - 2.008 0.497 - 346.3 1 2 0 -0.0001 10 0 0 0 1.43E+08 8.75E+07 - - - 4.6577 0.9999 221125_WJC_METTL3_EV_vs_WT_F02.21059.21059.2 1.43E-05 13/26 R.NLTYSAPLYVDITK[136.11].T "sp|P30876|RPB2_HUMAN,tr|C9J4M6|C9J4M6_HUMAN,tr|C9J2Y9|C9J2Y9_HUMAN" 3 1604.8541 1.09 20008 21059 2 1604.854241 803.4343 DNA-directed RNA polymerase II subunit RPB2 OS=Homo sapiens OX=9606 GN=POLR2B PE=1 SV=1 5.83 3580.5 - 2.85E+06 - - - 0.0723 - 2.454 0.509 - 496.2 1 2 0 0.0001 14 0 0 0 2.25E+07 2.06E+07 - - - 5.0532 1 221125_WJC_METTL3_EV_vs_WT_F02.21060.21060.3 3.10E-07 15/40 K.NAVEEYVYEFR[166.11].D "sp|Q92598|HS105_HUMAN,tr|A0A0A0MSM0|A0A0A0MSM0_HUMAN" 2 1427.6597 0.12 20009 21060 3 1427.659734 476.8938 Heat shock protein 105 kDa OS=Homo sapiens OX=9606 GN=HSPH1 PE=1 SV=1 4.25 3580.6 - 2.73E+06 - - - 0.0483 - 2.335 0.556 - 315.8 1 2 0 0.0001 11 0 0 0 5.07E+06 4.08E+07 - - - 7.1479 1 221125_WJC_METTL3_EV_vs_WT_F02.21062.21062.3 8.81E-06 14/48 R.IDILDSALLRPGR.L sp|P62195|PRS8_HUMAN 1 1437.8304 0.77 20011 21062 3 1437.828625 480.2841 26S proteasome regulatory subunit 8 OS=Homo sapiens OX=9606 GN=PSMC5 PE=1 SV=1 5.96 3580.7 - 2.51E+06 - - - -1.2088 - 2.709 0.433 - 307.4 1 2 0 -0.0017 13 0 0 0 3.54E+07 4.60E+07 - - - 6.0691 0.9999 221125_WJC_METTL3_EV_vs_WT_F02.21063.21063.3 3.44E-07 14/44 R.MKIELFADVVPK.T "sp|O43447|PPIH_HUMAN,tr|A0A7I2V2H6|A0A7I2V2H6_HUMAN,tr|A0A7I2V343|A0A7I2V343_HUMAN,tr|A0A7I2V5V0|A0A7I2V5V0_HUMAN,tr|C9JQD4|C9JQD4_HUMAN" 5 1388.7738 2.73 20012 21063 3 1388.773462 463.9319 Peptidyl-prolyl cis-trans isomerase H OS=Homo sapiens OX=9606 GN=PPIH PE=1 SV=1 5.82 3580.8 - 2.15E+06 - - - -0.2139 - 2.668 0.563 - 239.1 1 2 1 -0.0003 12 0 0 0 1.57E+07 5.75E+06 - - - 7.5369 0.9998 221125_WJC_METTL3_EV_vs_WT_F02.21064.21064.2 0.198 18-Nov R.DFLLKPELLR.A "sp|Q13838|DX39B_HUMAN,sp|O00148|DX39A_HUMAN,tr|K7EL56|K7EL56_HUMAN,tr|K7EPJ3|K7EPJ3_HUMAN,tr|F6U6E2|F6U6E2_HUMAN,tr|F6TRA5|F6TRA5_HUMAN,tr|A0A0G2JHN7|A0A0G2JHN7_HUMAN,tr|F6S2B7|F6S2B7_HUMAN,tr|F6WLT2|F6WLT2_HUMAN,tr|Q5STU3|Q5STU3_HUMAN,tr|F6R6M7|F6R6M7_HUMAN,tr|F6QYI9|F6QYI9_HUMAN,tr|K7ENP6|K7ENP6_HUMAN,tr|A0A0G2JJL7|A0A0G2JJL7_HUMAN,tr|K7EIL8|K7EIL8_HUMAN,tr|K7EQN7|K7EQN7_HUMAN,tr|K7EN69|K7EN69_HUMAN,tr|F6S4E6|F6S4E6_HUMAN,tr|A0A0A0MT12|A0A0A0MT12_HUMAN,tr|F6SXL5|F6SXL5_HUMAN" 20 1242.7336 1.39 20013 21064 2 1242.73493 622.3741 Spliceosome RNA helicase DDX39B OS=Homo sapiens OX=9606 GN=DDX39B PE=1 SV=1 6.07 3580.9 - 1.90E+06 - - - 1.063 - 2.15 0.415 - 562.2 1 2 0 0.0013 10 0 0 0 2.38E+07 1.71E+07 - - - 4.2424 1 221125_WJC_METTL3_EV_vs_WT_F02.21065.21065.2 4.33E-12 19/30 K.IAVYSC[160.03]PFDGMITETK.G sp|P50990|TCPQ_HUMAN 1 1830.8532 0.36 20014 21065 2 1830.852425 916.4339 T-complex protein 1 subunit theta OS=Homo sapiens OX=9606 GN=CCT8 PE=1 SV=4 4.37 3581 - 1.82E+06 - - - -0.4277 - 3.149 0.619 - 984.9 1 2 0 -0.0008 16 0 0 0 1.04E+08 2.87E+08 - - - 6.4328 0.9999 221125_WJC_METTL3_EV_vs_WT_F02.21066.21066.2 2.41E-08 14/26 K.VGTSFSIPVVSDVR.E "sp|Q92979|NEP1_HUMAN,tr|V9GYP5|V9GYP5_HUMAN,tr|A0A087WWQ2|A0A087WWQ2_HUMAN" 3 1461.7827 0.1 20015 21066 2 1461.784745 731.8986 Ribosomal RNA small subunit methyltransferase NEP1 OS=Homo sapiens OX=9606 GN=EMG1 PE=1 SV=4 5.81 3581.2 - 1.72E+06 - - - 1.3689 - 2.863 0.543 - 401 1 2 0 0.002 14 0 0 0 2.77E+07 2.73E+08 - - - 5.6906 1 221125_WJC_METTL3_EV_vs_WT_F02.21067.21067.2 5.33E-10 14/28 R.LILYNDGDSLQYIER[166.11].D sp|P53350|PLK1_HUMAN 1 1820.9184 0.67 20016 21067 2 1820.918481 911.4665 Serine\threonine-protein kinase PLK1 OS=Homo sapiens OX=9606 GN=PLK1 PE=1 SV=1 4.03 3581.3 - 844121 - - - 0.045 - 2.996 0.624 - 625.9 1 2 0 0.0001 15 0 0 0 3.01E+06 4.52E+06 - - - 6.3475 0.9954 221125_WJC_METTL3_EV_vs_WT_F02.21071.21071.3 0.00051 13/52 K.LLHHLSDLALTLPT.D "sp|Q86U44|MTA70_HUMAN,tr|B4E349|B4E349_HUMAN,tr|F5H6D8|F5H6D8_HUMAN,tr|H0YFV6|H0YFV6_HUMAN,tr|B4DTN4|B4DTN4_HUMAN" 5 1542.877 - 20018 21071 3 1542.876829 515.2996 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 5.97 3581.8 - 1.28E+07 - - - -0.0972 - 2.927 0.418 - 153.5 1 1 0 -0.0001 14 0 0 0 - - - - - 6.0544 0.9998 221125_WJC_METTL3_EV_vs_WT_F02.21072.21072.2 1.86E-05 16-Oct K.MC[160.03]LFAGFQR.K "sp|Q00839|HNRPU_HUMAN,tr|A0A1W2PQL0|A0A1W2PQL0_HUMAN,tr|A0A1W2PPL4|A0A1W2PPL4_HUMAN,tr|A0A1W2PQ74|A0A1W2PQ74_HUMAN,tr|Q5RI18|Q5RI18_HUMAN,tr|A0A1W2PP35|A0A1W2PP35_HUMAN,tr|A0A1W2PPS1|A0A1W2PPS1_HUMAN,tr|A0A1W2PRZ7|A0A1W2PRZ7_HUMAN,tr|A0A1W2PPH7|A0A1W2PPH7_HUMAN,tr|A0A1W2PQD4|A0A1W2PQD4_HUMAN,tr|A0A1W2PP34|A0A1W2PP34_HUMAN,tr|A0A1X7SBS1|A0A1X7SBS1_HUMAN" 12 1128.5209 0.9 20019 21072 2 1128.521194 565.2677 Heterogeneous nuclear ribonucleoprotein U OS=Homo sapiens OX=9606 GN=HNRNPU PE=1 SV=6 8 3581.8 - 2.03E+07 - - - 0.2995 - 2.074 0.384 - 609 1 2 0 0.0003 9 0 0 0 6.29E+08 7.01E+08 - - - 3.9875 1 221125_WJC_METTL3_EV_vs_WT_F02.21073.21073.3 4.76E-06 22/64 R.VYAILTHGIFSGPAISR.L "sp|P60891|PRPS1_HUMAN,sp|P11908|PRPS2_HUMAN,sp|P21108|PRPS3_HUMAN,tr|A0A2R8Y7H4|A0A2R8Y7H4_HUMAN,tr|B1ALA9|B1ALA9_HUMAN,tr|A0A6Q8PGP2|A0A6Q8PGP2_HUMAN,tr|H7C540|H7C540_HUMAN,tr|A0A0A0MRQ9|A0A0A0MRQ9_HUMAN,tr|A0A0B4J207|A0A0B4J207_HUMAN" 9 1800.9887 0.93 20020 21073 3 1800.990933 601.3368 Ribose-phosphate pyrophosphokinase 1 OS=Homo sapiens OX=9606 GN=PRPS1 PE=1 SV=2 8.73 3581.8 - 7.87E+06 - - - 1.2654 - 3.873 0.576 - 493.1 1 2 0 0.0023 17 0 0 0 3.50E+07 3.77E+07 - - - 8.3819 1 221125_WJC_METTL3_EV_vs_WT_F02.21074.21074.3 1.80E-07 17/64 R.VYAILTHGIFSGPAISR[166.11].L "sp|P60891|PRPS1_HUMAN,sp|P11908|PRPS2_HUMAN,sp|P21108|PRPS3_HUMAN,tr|A0A2R8Y7H4|A0A2R8Y7H4_HUMAN,tr|B1ALA9|B1ALA9_HUMAN,tr|A0A6Q8PGP2|A0A6Q8PGP2_HUMAN,tr|H7C540|H7C540_HUMAN,tr|A0A0A0MRQ9|A0A0A0MRQ9_HUMAN,tr|A0A0B4J207|A0A0B4J207_HUMAN" 9 1810.9969 0.96 20021 21074 3 1810.999649 604.6729 Ribose-phosphate pyrophosphokinase 1 OS=Homo sapiens OX=9606 GN=PRPS1 PE=1 SV=2 8.73 3581.9 - 7.58E+06 - - - 1.5047 - 3.46 0.547 - 258.3 1 2 0 0.0027 17 0 0 0 3.63E+07 3.77E+07 - - - 7.7736 1 221125_WJC_METTL3_EV_vs_WT_F02.21075.21075.3 3.98E-05 Dec-52 R.FGFPEGSVELYAEK.V "sp|P23396|RS3_HUMAN,tr|F2Z2S8|F2Z2S8_HUMAN,tr|H0YCJ7|H0YCJ7_HUMAN,tr|E9PPU1|E9PPU1_HUMAN,tr|H0YF32|H0YF32_HUMAN" 5 1571.7508 0.67 20022 21075 3 1571.751352 524.9242 40S ribosomal protein S3 OS=Homo sapiens OX=9606 GN=RPS3 PE=1 SV=2 4.25 3581.9 - 3.41E+06 - - - 0.3671 - 2.212 0.478 - 131.3 1 2 0 0.0006 14 0 0 0 2.62E+07 3.90E+07 - - - 5.9789 0.9996 221125_WJC_METTL3_EV_vs_WT_F02.21076.21076.2 0.000455 26-Oct R.NLTYSAPLYVDITK.T "sp|P30876|RPB2_HUMAN,tr|C9J4M6|C9J4M6_HUMAN,tr|C9J2Y9|C9J2Y9_HUMAN" 3 1596.8399 1.09 20023 21076 2 1596.843973 799.4272 DNA-directed RNA polymerase II subunit RPB2 OS=Homo sapiens OX=9606 GN=POLR2B PE=1 SV=1 5.83 3582 - 2.63E+06 - - - 2.535 - 2.269 0.49 - 262.5 1 2 0 0.004 14 0 0 0 2.25E+07 2.06E+07 - - - 4.715 0.9999 221125_WJC_METTL3_EV_vs_WT_F02.21077.21077.2 0.000151 15/26 K.GFGFVDFNSEEDAK.A "sp|P19338|NUCL_HUMAN,tr|A0A7I2V699|A0A7I2V699_HUMAN,tr|A0A7I2V3F3|A0A7I2V3F3_HUMAN,tr|A0A7I2V428|A0A7I2V428_HUMAN,tr|H7BY16|H7BY16_HUMAN,tr|A0A7I2V5M5|A0A7I2V5M5_HUMAN,tr|C9JLB1|C9JLB1_HUMAN" 7 1560.6733 4.99 20024 21077 2 1560.671583 781.3439 Nucleolin OS=Homo sapiens OX=9606 GN=NCL PE=1 SV=3 3.92 3582.1 - 2.49E+06 - - - -1.0701 - 2.89 0.54 - 673.4 1 2 0 -0.0017 14 0 0 0 2.55E+07 5.11E+06 - - - 5.6921 0.9996 221125_WJC_METTL3_EV_vs_WT_F02.21078.21078.2 7.75E-08 14/24 K.DIPVLVATDVAAR.G "sp|Q86XP3|DDX42_HUMAN,tr|A0A0A0MSJ0|A0A0A0MSJ0_HUMAN" 2 1338.7507 1.19 20025 21078 2 1338.753797 670.3826 ATP-dependent RNA helicase DDX42 OS=Homo sapiens OX=9606 GN=DDX42 PE=1 SV=1 4.21 3582.2 - 1.98E+06 - - - 2.3014 - 2.606 0.437 - 650.6 1 2 0 0.0031 13 0 0 0 2.29E+07 1.92E+07 - - - 4.726 0.9989 221125_WJC_METTL3_EV_vs_WT_F02.21080.21080.2 5.44E-05 13/24 K.DIPVLVATDVAAR[166.11].G "sp|Q86XP3|DDX42_HUMAN,tr|A0A0A0MSJ0|A0A0A0MSJ0_HUMAN" 2 1348.759 1.24 20027 21080 2 1348.755165 675.3868 ATP-dependent RNA helicase DDX42 OS=Homo sapiens OX=9606 GN=DDX42 PE=1 SV=1 4.21 3582.4 - 1.65E+06 - - - -2.833 - 2.412 0.321 - 533.2 1 2 0 -0.0038 13 0 0 0 2.29E+07 1.85E+07 - - - 3.6704 1 221125_WJC_METTL3_EV_vs_WT_F02.21081.21081.3 5.04E-08 17/72 R.VLIVSEDPELPYMRPPLSK.E "sp|O95831|AIFM1_HUMAN,tr|A0A6Q8PFW2|A0A6Q8PFW2_HUMAN,tr|A0A6Q8PFA7|A0A6Q8PFA7_HUMAN,tr|A0A6Q8PHJ9|A0A6Q8PHJ9_HUMAN,tr|A0A6Q8PFS4|A0A6Q8PFS4_HUMAN,tr|A0A7I2PK44|A0A7I2PK44_HUMAN,tr|A0A6Q8PF87|A0A6Q8PF87_HUMAN,tr|A0A6Q8PG15|A0A6Q8PG15_HUMAN,tr|A0A6Q8PFE1|A0A6Q8PFE1_HUMAN,tr|A0A7I2RLJ8|A0A7I2RLJ8_HUMAN,tr|A0A6Q8PFQ8|A0A6Q8PFQ8_HUMAN,tr|A0A6Q8PHC0|A0A6Q8PHC0_HUMAN,tr|A0A6Q8PFM5|A0A6Q8PFM5_HUMAN" 13 2182.1708 0.37 20028 21081 3 2182.166178 728.3975 "Apoptosis-inducing factor 1, mitochondrial OS=Homo sapiens OX=9606 GN=AIFM1 PE=1 SV=1" 4.68 3582.5 - 1.63E+06 - - - -2.108 - 3.327 0.573 - 273.2 1 2 0 -0.0046 19 0 0 0 8.18E+06 2.20E+07 - - - 7.8804 1 221125_WJC_METTL3_EV_vs_WT_F02.21082.21082.2 1.60E-09 16/30 K.LYVPVKEYPDFNFVGR.L "sp|Q96PU8|QKI_HUMAN,tr|F5H5U6|F5H5U6_HUMAN,tr|F5GYM3|F5GYM3_HUMAN,tr|F5GXS8|F5GXS8_HUMAN,tr|F5H8C8|F5H8C8_HUMAN" 5 1941.9989 -1 20029 21082 2 1942.001052 972.0067 Protein quaking OS=Homo sapiens OX=9606 GN=QKI PE=1 SV=1 6.07 3582.6 - 1.34E+06 - - - 1.1159 - 2.695 0.684 - 695.8 1 2 1 0.0022 16 0 0 0 0.00E+00 0.00E+00 - - - 6.5297 0.9995 221125_WJC_METTL3_EV_vs_WT_F02.21083.21083.2 0.00757 16-Aug K.GLDFALLQK.V "sp|Q13123|RED_HUMAN,tr|D6REL4|D6REL4_HUMAN,tr|E7EQZ7|E7EQZ7_HUMAN" 3 1003.5702 1.09 20030 21083 2 1003.570305 502.7924 Protein Red OS=Homo sapiens OX=9606 GN=IK PE=1 SV=3 5.84 3582.7 - 1.31E+06 - - - 0.0727 - 1.656 0.336 - 173 1 2 0 0.0001 9 0 0 0 1.02E+07 9.34E+06 - - - 2.9819 0.9999 221125_WJC_METTL3_EV_vs_WT_F02.21085.21085.3 4.79E-06 13/40 K.NAVEEYVYEFR.D "sp|Q92598|HS105_HUMAN,tr|A0A0A0MSM0|A0A0A0MSM0_HUMAN" 2 1417.6514 0.12 20032 21085 3 1417.653899 473.5577 Heat shock protein 105 kDa OS=Homo sapiens OX=9606 GN=HSPH1 PE=1 SV=1 4.25 3583 - 1.06E+06 - - - 1.7663 - 2.178 0.469 - 219.9 1 2 0 0.0025 11 0 0 0 4.86E+06 4.06E+07 - - - 5.9795 0.9989 221125_WJC_METTL3_EV_vs_WT_F02.21086.21086.3 0.00156 13/48 R.VFITDDFHDMMPK.Y "sp|P14625|ENPL_HUMAN,tr|A0A7P0T917|A0A7P0T917_HUMAN,tr|A0A7P0T823|A0A7P0T823_HUMAN,tr|A0A7P0TAE1|A0A7P0TAE1_HUMAN,tr|H0YIV0|H0YIV0_HUMAN,tr|A0A7P0TAY2|A0A7P0TAY2_HUMAN,tr|A0A087WT78|A0A087WT78_HUMAN,tr|A0A7P0TBC2|A0A7P0TBC2_HUMAN,tr|A0A7P0TAT8|A0A7P0TAT8_HUMAN" 9 1594.716 0.61 20033 21086 3 1594.720165 532.5793 Endoplasmin OS=Homo sapiens OX=9606 GN=HSP90B1 PE=1 SV=1 4.41 3583.1 - 1.02E+06 - - - 2.6205 - 1.981 0.33 - 75 1 2 0 0.0042 13 0 0 0 8.16E+06 1.33E+07 - - - 4.0715 0.998 221125_WJC_METTL3_EV_vs_WT_F02.21089.21089.3 0.0154 Sep-40 K.GSLLWVLDHTK[136.11].T "sp|P20585|MSH3_HUMAN,tr|A0A590UKC9|A0A590UKC9_HUMAN,tr|A0A590UJW0|A0A590UJW0_HUMAN" 3 1275.7067 0.54 20036 21089 3 1275.707163 426.2428 DNA mismatch repair protein Msh3 OS=Homo sapiens OX=9606 GN=MSH3 PE=1 SV=4 6.74 3583.5 - 662563 - - - 0.3849 - 1.546 0.274 - 82.1 1 2 0 0.0005 11 0 0 0 1.41E+06 2.62E+06 - - - 2.8324 1 221125_WJC_METTL3_EV_vs_WT_F02.21090.21090.2 2.73E-10 20/28 R.LTEMETLQSQLMAEK[136.11].L sp|P35579|MYH9_HUMAN 1 1758.8623 1.4 20037 21090 2 1759.868426 880.4384 Myosin-9 OS=Homo sapiens OX=9606 GN=MYH9 PE=1 SV=4 4.25 3583.6 - 659038 - - - 572.0192 - 3.709 0.654 - 1655.3 1 2 0 1.0061 15 0 0 0 3.09E+07 2.21E+07 - - - 6.7781 1 221125_WJC_METTL3_EV_vs_WT_F02.21094.21094.2 3.10E-08 13/22 R.YISPDQLADLYK.S "sp|P06733|ENOA_HUMAN,tr|A0A2R8Y6G6|A0A2R8Y6G6_HUMAN" 2 1424.7187 1.54 20040 21094 2 1424.718247 713.3666 Alpha-enolase OS=Homo sapiens OX=9606 GN=ENO1 PE=1 SV=2 4.21 3584 - 3.84E+07 - - - -0.3509 - 2.586 0.646 - 431.2 1 2 0 -0.0005 12 0 0 0 5.19E+08 3.37E+08 - - - 6.3121 0.9997 221125_WJC_METTL3_EV_vs_WT_F02.21095.21095.2 0.0216 18-Nov R.DIDEVSSLLR[166.11].T "sp|P50990|TCPQ_HUMAN,tr|H7C4C8|H7C4C8_HUMAN" 2 1155.6011 0.41 20041 21095 2 1155.599682 578.8078 T-complex protein 1 subunit theta OS=Homo sapiens OX=9606 GN=CCT8 PE=1 SV=4 4.03 3584.1 - 1.84E+07 - - - -1.2167 - 2.204 0.388 - 379.9 1 2 0 -0.0014 10 0 0 0 4.28E+08 1.05E+09 - - - 4.1122 1 221125_WJC_METTL3_EV_vs_WT_F02.21096.21096.3 5.35E-07 15/60 K.SLLSQEKEELQMSLLK.L sp|Q15643|TRIPB_HUMAN 1 1875.0023 0.97 20042 21096 3 1875.003406 626.008 Thyroid receptor-interacting protein 11 OS=Homo sapiens OX=9606 GN=TRIP11 PE=1 SV=3 4.78 3584.1 - 1.28E+07 - - - 0.5819 - 3.258 0.591 - 207.4 1 2 1 0.0011 16 0 0 0 7.48E+07 7.74E+07 - - - 8.1593 1 221125_WJC_METTL3_EV_vs_WT_F02.21097.21097.3 1.79E-07 13/60 K.IAVYSC[160.03]PFDGMITETK[136.11].G sp|P50990|TCPQ_HUMAN 1 1838.8674 0.34 20043 21097 3 1838.867034 613.9631 T-complex protein 1 subunit theta OS=Homo sapiens OX=9606 GN=CCT8 PE=1 SV=4 4.37 3584.1 - 9.90E+06 - - - -0.2034 - 2.523 0.559 - 274.5 1 2 0 -0.0004 16 0 0 0 1.86E+07 5.52E+07 - - - 7.1468 0.9999 221125_WJC_METTL3_EV_vs_WT_F02.21098.21098.2 5.28E-07 20-Nov K.GTNYLADVFEK.K sp|P31151|S10A7_HUMAN 1 1255.6085 0.22 20044 21098 2 1255.608692 628.8115 Protein S100-A7 OS=Homo sapiens OX=9606 GN=S100A7 PE=1 SV=4 4.37 3584.2 - 9.68E+06 - - - 0.1784 - 2.453 0.536 - 574 1 2 0 0.0002 11 0 0 0 2.72E+08 1.25E+09 - - - 5.4273 0.9998 221125_WJC_METTL3_EV_vs_WT_F02.21100.21100.2 0.000223 14/28 R.AILVDLEPGTMDSVR[166.11].S "sp|Q9BVA1|TBB2B_HUMAN,sp|P07437|TBB5_HUMAN,sp|Q13509|TBB3_HUMAN,sp|Q13885|TBB2A_HUMAN,tr|A0A0B4J269|A0A0B4J269_HUMAN,tr|Q5JP53|Q5JP53_HUMAN,tr|G3V3R4|G3V3R4_HUMAN,tr|G3V5W4|G3V5W4_HUMAN,tr|G3V2R8|G3V2R8_HUMAN,tr|G3V2N6|G3V2N6_HUMAN" 10 1624.837 0.67 20046 21100 2 1624.83876 813.4258 Tubulin beta-2B chain OS=Homo sapiens OX=9606 GN=TUBB2B PE=1 SV=1 4.03 3584.3 - 4.23E+06 - - - 1.0967 - 2.388 0.431 - 422.6 1 2 0 0.0018 15 0 0 0 2.81E+08 4.18E+08 - - - 4.3639 1 221125_WJC_METTL3_EV_vs_WT_F02.21101.21101.3 2.43E-08 15/60 K.IAVYSC[160.03]PFDGMITETK.G sp|P50990|TCPQ_HUMAN 1 1830.8532 0.34 20047 21101 3 1830.85208 611.2917 T-complex protein 1 subunit theta OS=Homo sapiens OX=9606 GN=CCT8 PE=1 SV=4 4.37 3584.3 - 3.13E+06 - - - -0.6161 - 2.737 0.516 - 359.9 1 2 0 -0.0011 16 0 0 0 1.86E+07 5.52E+07 - - - 6.8761 1 221125_WJC_METTL3_EV_vs_WT_F02.21102.21102.2 7.63E-08 16/28 K.SSIDSEPALVLGPLK.S "sp|Q15155|NOMO1_HUMAN,sp|Q5JPE7|NOMO2_HUMAN,sp|P69849|NOMO3_HUMAN,tr|A0A7I2V3P4|A0A7I2V3P4_HUMAN,tr|A0A7I2V6B0|A0A7I2V6B0_HUMAN,tr|A0A7I2V4D7|A0A7I2V4D7_HUMAN,tr|A0A7I2V4T6|A0A7I2V4T6_HUMAN,tr|A0A0G2JP90|A0A0G2JP90_HUMAN,tr|A0A087X117|A0A087X117_HUMAN,tr|A0A0G2JN29|A0A0G2JN29_HUMAN,tr|A0A7I2V2Z5|A0A7I2V2Z5_HUMAN,tr|A0A087WW46|A0A087WW46_HUMAN,tr|J3KN36|J3KN36_HUMAN" 13 1524.8399 2.1 20048 21102 2 1524.847219 763.4272 Nodal modulator 1 OS=Homo sapiens OX=9606 GN=NOMO1 PE=1 SV=5 4.37 3584.4 - 2.92E+06 - - - 4.7835 - 3.208 0.592 - 734.9 1 2 0 0.0073 15 0 0 0 4.62E+07 2.20E+07 - - - 6.277 1 221125_WJC_METTL3_EV_vs_WT_F02.21103.21103.2 3.20E-10 16/28 R.LTEMETLQSQLMAEK.L sp|P35579|MYH9_HUMAN 1 1750.8481 1.4 20049 21103 2 1750.847677 876.4313 Myosin-9 OS=Homo sapiens OX=9606 GN=MYH9 PE=1 SV=4 4.25 3584.5 - 2.69E+06 - - - -0.2547 - 3.31 0.545 - 908.3 1 2 0 -0.0004 15 0 0 0 3.09E+07 2.21E+07 - - - 6.009 0.9896 221125_WJC_METTL3_EV_vs_WT_F02.21104.21104.2 0.000738 20-Sep M.LEPSANMPWFK[136.11].G "sp|P68104|EF1A1_HUMAN,sp|Q5VTE0|EF1A3_HUMAN,tr|A0A7I2V659|A0A7I2V659_HUMAN,tr|A0A7I2V3H3|A0A7I2V3H3_HUMAN,tr|A0A7I2V5N4|A0A7I2V5N4_HUMAN,tr|A0A087WVQ9|A0A087WVQ9_HUMAN,tr|A0A087WV01|A0A087WV01_HUMAN" 7 1326.6522 0.13 20050 21104 2 1326.651259 664.3334 Elongation factor 1-alpha 1 OS=Homo sapiens OX=9606 GN=EEF1A1 PE=1 SV=1 6 3584.6 - 2.54E+06 - - - -0.7048 - 1.924 0.483 - 303.8 1 1 0 -0.0009 11 0 0 0 3.83E+06 2.84E+07 - - - 4.3785 1 221125_WJC_METTL3_EV_vs_WT_F02.21105.21105.2 3.54E-10 20/28 R.LTEMETLQSQLMAEK[136.11].L sp|P35579|MYH9_HUMAN 1 1758.8623 1.4 20051 21105 2 1758.857694 880.4384 Myosin-9 OS=Homo sapiens OX=9606 GN=MYH9 PE=1 SV=4 4.25 3584.8 - 2.45E+06 - - - -2.6318 - 3.761 0.684 - 1743.6 1 2 0 -0.0046 15 0 0 0 3.09E+07 2.21E+07 - - - 7.3484 0.9999 221125_WJC_METTL3_EV_vs_WT_F02.21106.21106.3 8.34E-05 15/44 R.VYEFLDK[136.11]LDVVR[166.11].S "sp|O43242|PSMD3_HUMAN,tr|H0YGV8|H0YGV8_HUMAN" 2 1512.8307 1.01 20052 21106 3 1512.828334 505.2842 26S proteasome non-ATPase regulatory subunit 3 OS=Homo sapiens OX=9606 GN=PSMD3 PE=1 SV=2 4.56 3584.8 - 1.89E+06 - - - -1.564 - 2.789 0.498 - 306.6 1 2 1 -0.0024 12 0 0 0 8.27E+06 8.18E+06 - - - 6.9346 0.9998 221125_WJC_METTL3_EV_vs_WT_F02.21107.21107.2 2.65E-07 14/24 R.LDVTVQSFGWSDR.A "sp|Q8NCA5|FA98A_HUMAN,sp|Q52LJ0|FA98B_HUMAN,tr|E9PH82|E9PH82_HUMAN" 3 1508.726 0.04 20053 21107 2 1508.72267 755.3703 Protein FAM98A OS=Homo sapiens OX=9606 GN=FAM98A PE=1 SV=2 4.21 3584.9 - 1.40E+06 - - - -2.1787 - 2.873 0.482 - 805.3 1 2 0 -0.0033 13 0 0 0 8.03E+06 1.96E+08 - - - 5.3086 1 221125_WJC_METTL3_EV_vs_WT_F02.21108.21108.2 7.62E-10 16/30 K.SLLSQEKEELQMSLLK.L sp|Q15643|TRIPB_HUMAN 1 1875.0023 0.83 20054 21108 2 1875.003347 938.5084 Thyroid receptor-interacting protein 11 OS=Homo sapiens OX=9606 GN=TRIP11 PE=1 SV=3 4.78 3585.1 - 1.09E+06 - - - 0.5504 - 3.611 0.683 - 607.6 1 2 1 0.001 16 0 0 0 5.22E+06 6.30E+06 - - - 7.242 0.9535 221125_WJC_METTL3_EV_vs_WT_F02.21109.21109.2 0.0834 20-Oct K.LPQLPITNFSR.D "sp|P21333|FLNA_HUMAN,tr|A0A7P0NMY4|A0A7P0NMY4_HUMAN,tr|Q60FE5|Q60FE5_HUMAN,tr|A0A7I2V3E6|A0A7I2V3E6_HUMAN,tr|A0A087WWY3|A0A087WWY3_HUMAN,tr|F8WE98|F8WE98_HUMAN" 6 1284.719 1.3 20055 21109 2 1284.727074 643.3668 Filamin-A OS=Homo sapiens OX=9606 GN=FLNA PE=1 SV=4 9.75 3585.2 - 1.02E+06 - - - 6.2683 - 1.739 0.242 - 278.9 1 2 0 0.0081 11 0 0 0 1.40E+07 1.08E+07 - - - 2.3227 0.9999 221125_WJC_METTL3_EV_vs_WT_F02.21111.21111.3 0.00125 Dec-52 R.SLLGVAATLAPGSR.G sp|Q8TAE8|G45IP_HUMAN 1 1311.7511 4.49 20057 21111 3 1311.75141 438.2576 Growth arrest and DNA damage-inducible proteins-interacting protein 1 OS=Homo sapiens OX=9606 GN=GADD45GIP1 PE=1 SV=1 9.47 3585.4 - 617856 - - - 0.2744 - 2.172 0.391 - 168.1 1 2 0 0.0004 14 0 0 0 2.43E+06 5.42E+05 - - - 4.9605 0.9999 221125_WJC_METTL3_EV_vs_WT_F02.21117.21117.3 3.02E-06 15/44 K.VVLDDK[136.11]DYFLFR[166.11].D "sp|P61604|CH10_HUMAN,tr|B8ZZ54|B8ZZ54_HUMAN" 2 1546.815 0.65 20062 21117 3 1546.815607 516.6123 "10 kDa heat shock protein, mitochondrial OS=Homo sapiens OX=9606 GN=HSPE1 PE=1 SV=2" 4.43 3585.9 - 8.57E+06 - - - 0.3601 - 3.146 0.54 - 369.5 1 2 1 0.0006 12 0 0 0 3.48E+07 5.34E+07 - - - 7.7372 1 221125_WJC_METTL3_EV_vs_WT_F02.21118.21118.3 7.49E-07 15/60 K.SLLSQEK[136.11]EELQMSLLK[136.11].L sp|Q15643|TRIPB_HUMAN 1 1891.0307 1.14 20063 21118 3 1891.030273 631.3508 Thyroid receptor-interacting protein 11 OS=Homo sapiens OX=9606 GN=TRIP11 PE=1 SV=3 4.78 3585.9 - 8.31E+06 - - - -0.2337 - 2.968 0.631 - 166.2 1 2 1 -0.0004 16 0 0 0 7.40E+07 6.47E+07 - - - 8.3663 0.9999 221125_WJC_METTL3_EV_vs_WT_F02.21119.21119.2 0.000372 16/28 R.AILVDLEPGTMDSVR.S "sp|Q9BVA1|TBB2B_HUMAN,sp|P07437|TBB5_HUMAN,sp|Q13509|TBB3_HUMAN,sp|Q13885|TBB2A_HUMAN,tr|A0A0B4J269|A0A0B4J269_HUMAN,tr|Q5JP53|Q5JP53_HUMAN,tr|G3V3R4|G3V3R4_HUMAN,tr|G3V5W4|G3V5W4_HUMAN,tr|G3V2R8|G3V2R8_HUMAN,tr|G3V2N6|G3V2N6_HUMAN" 10 1614.8287 0.67 20064 21119 2 1614.830605 808.4216 Tubulin beta-2B chain OS=Homo sapiens OX=9606 GN=TUBB2B PE=1 SV=1 4.03 3586 - 7.55E+06 - - - 1.1747 - 3.122 0.468 - 604.6 1 2 0 0.0019 15 0 0 0 2.81E+08 4.18E+08 - - - 5.296 0.9998 221125_WJC_METTL3_EV_vs_WT_F02.21120.21120.3 0.128 15/72 R.VLIVSEDPELPYMR[166.11]PPLSK[136.11].E "sp|O95831|AIFM1_HUMAN,tr|A0A6Q8PFW2|A0A6Q8PFW2_HUMAN,tr|A0A6Q8PFA7|A0A6Q8PFA7_HUMAN,tr|A0A6Q8PHJ9|A0A6Q8PHJ9_HUMAN,tr|A0A6Q8PFS4|A0A6Q8PFS4_HUMAN,tr|A0A7I2PK44|A0A7I2PK44_HUMAN,tr|A0A6Q8PF87|A0A6Q8PF87_HUMAN,tr|A0A6Q8PG15|A0A6Q8PG15_HUMAN,tr|A0A6Q8PFE1|A0A6Q8PFE1_HUMAN,tr|A0A7I2RLJ8|A0A7I2RLJ8_HUMAN,tr|A0A6Q8PFQ8|A0A6Q8PFQ8_HUMAN,tr|A0A6Q8PHC0|A0A6Q8PHC0_HUMAN,tr|A0A6Q8PFM5|A0A6Q8PFM5_HUMAN" 13 2200.1932 0.58 20065 21120 3 2200.193018 734.405 "Apoptosis-inducing factor 1, mitochondrial OS=Homo sapiens OX=9606 GN=AIFM1 PE=1 SV=1" 4.68 3586 - 5.73E+06 - - - -0.1045 - 2.306 0.357 - 188.2 1 2 0 -0.0002 19 0 0 0 2.30E+07 3.95E+07 - - - 4.5728 1 221125_WJC_METTL3_EV_vs_WT_F02.21121.21121.2 5.16E-06 17/26 K.TGGLEIDSDFGGFR[166.11].V "sp|O95831|AIFM1_HUMAN,tr|A0A6Q8PFA7|A0A6Q8PFA7_HUMAN,tr|A0A6Q8PHJ9|A0A6Q8PHJ9_HUMAN,tr|A0A6Q8PFS4|A0A6Q8PFS4_HUMAN,tr|E9PMA0|E9PMA0_HUMAN,tr|A0A7I2PK44|A0A7I2PK44_HUMAN,tr|A0A6Q8PG15|A0A6Q8PG15_HUMAN,tr|A0A6Q8PFE1|A0A6Q8PFE1_HUMAN,tr|A0A7I2RLJ8|A0A7I2RLJ8_HUMAN,tr|A0A6Q8PFQ8|A0A6Q8PFQ8_HUMAN,tr|A0A6Q8PHC0|A0A6Q8PHC0_HUMAN,tr|A0A6Q8PFM5|A0A6Q8PFM5_HUMAN" 12 1479.6869 0.57 20066 21121 2 1479.688047 740.8507 "Apoptosis-inducing factor 1, mitochondrial OS=Homo sapiens OX=9606 GN=AIFM1 PE=1 SV=1" 4.03 3586.1 - 4.51E+06 - - - 0.7461 - 3.168 0.56 - 1042.4 1 2 0 0.0011 14 0 0 0 1.64E+07 2.87E+07 - - - 6.0705 0.9999 221125_WJC_METTL3_EV_vs_WT_F02.21122.21122.2 1.88E-05 18-Dec K.SVVTSIFGVK[136.11].N "sp|P41252|SYIC_HUMAN,tr|A0A804HL54|A0A804HL54_HUMAN,tr|A0A804HJN6|A0A804HJN6_HUMAN,tr|A0A0A0MSX9|A0A0A0MSX9_HUMAN" 4 1043.6106 0.86 20067 21122 2 1043.61107 522.8126 "Isoleucine--tRNA ligase, cytoplasmic OS=Homo sapiens OX=9606 GN=IARS1 PE=1 SV=2" 8.47 3586.1 - 4.47E+06 - - - 0.4053 - 2.228 0.464 - 371.7 1 2 0 0.0004 10 0 0 0 3.78E+07 4.38E+07 - - - 4.7041 0.9994 221125_WJC_METTL3_EV_vs_WT_F02.21124.21124.3 0.0161 Oct-56 R.LTEMETLQSQLMAEK[136.11].L sp|P35579|MYH9_HUMAN 1 1758.8623 1.13 20069 21124 3 1758.860352 587.2947 Myosin-9 OS=Homo sapiens OX=9606 GN=MYH9 PE=1 SV=4 4.25 3586.2 - 3.80E+06 - - - -1.1206 - 1.796 0.333 - 116.9 1 2 0 -0.002 15 0 0 0 2.32E+07 2.05E+07 - - - 3.78 0.9998 221125_WJC_METTL3_EV_vs_WT_F02.21126.21126.2 0.00187 13/18 K.SVVTSIFGVK.N "sp|P41252|SYIC_HUMAN,tr|A0A804HL54|A0A804HL54_HUMAN,tr|A0A804HJN6|A0A804HJN6_HUMAN,tr|A0A0A0MSX9|A0A0A0MSX9_HUMAN" 4 1035.5964 0.86 20071 21126 2 1035.596251 518.8055 "Isoleucine--tRNA ligase, cytoplasmic OS=Homo sapiens OX=9606 GN=IARS1 PE=1 SV=2" 8.47 3586.4 - 3.16E+06 - - - -0.1893 - 2.231 0.414 - 448.4 1 2 0 -0.0002 10 0 0 0 3.78E+07 4.38E+07 - - - 4.3386 0.9998 221125_WJC_METTL3_EV_vs_WT_F02.21129.21129.2 0.000234 20-Sep R.ESMLVEWEQVK.Q "sp|Q8N1F7|NUP93_HUMAN,tr|H3BM93|H3BM93_HUMAN,tr|H3BP95|H3BP95_HUMAN,tr|H3BNG7|H3BNG7_HUMAN,tr|H3BRI8|H3BRI8_HUMAN,tr|H3BNN5|H3BNN5_HUMAN,tr|H3BVG0|H3BVG0_HUMAN,tr|H3BMX0|H3BMX0_HUMAN" 8 1376.6646 1.95 20074 21129 2 1376.665657 689.3396 Nuclear pore complex protein Nup93 OS=Homo sapiens OX=9606 GN=NUP93 PE=1 SV=2 4.25 3586.6 - 2.27E+06 - - - 0.7656 - 2.065 0.444 - 304.7 1 2 0 0.0011 11 0 0 0 2.58E+07 1.32E+07 - - - 4.2817 0.9903 221125_WJC_METTL3_EV_vs_WT_F02.21132.21132.2 0.265 22-Nov K.SGSWAAIYQDIR.H sp|P18031|PTN1_HUMAN 1 1365.6677 3.11 20077 21132 2 1365.669046 683.8411 Tyrosine-protein phosphatase non-receptor type 1 OS=Homo sapiens OX=9606 GN=PTPN1 PE=1 SV=1 5.55 3586.9 - 1.60E+06 - - - 0.9753 - 1.338 0.138 - 95.1 1 2 0 0.0013 12 0 0 0 7.19E+06 2.31E+06 - - - 0.826 1 221125_WJC_METTL3_EV_vs_WT_F02.21137.21137.2 1.00E-07 16/24 R.TPFTTSQLLALER.K sp|P35548|MSX2_HUMAN 1 1475.7984 2.4 20081 21137 2 1475.798094 738.9065 Homeobox protein MSX-2 OS=Homo sapiens OX=9606 GN=MSX2 PE=1 SV=3 5.66 3587.4 - 7.02E+06 - - - -0.2033 - 3.161 0.644 - 1151.8 1 2 0 -0.0003 13 0 0 0 4.47E+07 1.87E+07 - - - 6.7513 1 221125_WJC_METTL3_EV_vs_WT_F02.21138.21138.2 3.14E-08 17/28 R.GLIVYQLENQPSEFR.R "sp|P78406|RAE1L_HUMAN,tr|E9PQ57|E9PQ57_HUMAN,tr|E9PPG9|E9PPG9_HUMAN" 3 1791.9155 1.89 20082 21138 2 1791.915212 896.9651 mRNA export factor OS=Homo sapiens OX=9606 GN=RAE1 PE=1 SV=1 4.53 3587.5 - 3.46E+06 - - - -0.1881 - 3.254 0.636 - 1020.4 1 2 0 -0.0003 15 0 0 0 1.60E+08 8.45E+07 - - - 6.6392 1 221125_WJC_METTL3_EV_vs_WT_F02.21140.21140.3 6.53E-08 14/56 R.GLIVYQLENQPSEFR.R "sp|P78406|RAE1L_HUMAN,tr|E9PQ57|E9PQ57_HUMAN,tr|E9PPG9|E9PPG9_HUMAN" 3 1791.9155 1.97 20084 21140 3 1791.915708 598.3125 mRNA export factor OS=Homo sapiens OX=9606 GN=RAE1 PE=1 SV=1 4.53 3587.6 - 3.10E+06 - - - 0.0887 - 2.667 0.572 - 235.5 1 2 0 0.0002 15 0 0 0 1.08E+08 5.47E+07 - - - 7.4769 0.9994 221125_WJC_METTL3_EV_vs_WT_F02.21142.21142.2 6.94E-08 18/28 M.VGQLSEGAIAAIMQK.G sp|P27694|RFA1_HUMAN 1 1514.8127 1.04 20086 21142 2 1514.818168 758.4136 Replication protein A 70 kDa DNA-binding subunit OS=Homo sapiens OX=9606 GN=RPA1 PE=1 SV=2 5.97 3587.8 - 2.31E+06 - - - 3.6335 - 3.281 0.498 - 949.1 1 2 0 0.0055 15 0 0 0 5.92E+07 5.69E+07 - - - 5.6386 1 221125_WJC_METTL3_EV_vs_WT_F02.21143.21143.2 8.45E-10 19/28 R.GLIVYQLENQPSEFR[166.11].R "sp|P78406|RAE1L_HUMAN,tr|E9PQ57|E9PQ57_HUMAN,tr|E9PPG9|E9PPG9_HUMAN" 3 1801.9238 1.89 20087 21143 2 1801.920617 901.9692 mRNA export factor OS=Homo sapiens OX=9606 GN=RAE1 PE=1 SV=1 4.53 3587.9 - 2.20E+06 - - - -1.777 - 3.345 0.658 - 1297.9 1 2 0 -0.0032 15 0 0 0 1.60E+08 8.45E+07 - - - 6.8686 1 221125_WJC_METTL3_EV_vs_WT_F02.21145.21145.2 9.75E-11 21/40 R.VYTADPYHALAPAASYGVGAV.A "sp|O43251|RFOX2_HUMAN,tr|B0QYV1|B0QYV1_HUMAN,tr|A0A0G2JRD1|A0A0G2JRD1_HUMAN,tr|A0A0G2JRA5|A0A0G2JRA5_HUMAN,tr|S4R3K7|S4R3K7_HUMAN" 5 2092.0266 - 20089 21145 2 2092.024231 1047.0206 RNA binding protein fox-1 homolog 2 OS=Homo sapiens OX=9606 GN=RBFOX2 PE=1 SV=3 5.08 3588.2 - 1.65E+06 - - - -1.1114 - 3.604 0.648 - 864.5 1 1 0 -0.0023 21 0 0 0 - - - - - 6.9784 0.9677 221125_WJC_METTL3_EV_vs_WT_F02.21146.21146.2 0.00384 22-Oct K.IIENELEGFGIR[166.11].L sp|Q9Y295|DRG1_HUMAN 1 1398.7383 0.21 20090 21146 2 1398.742778 700.3764 Developmentally-regulated GTP-binding protein 1 OS=Homo sapiens OX=9606 GN=DRG1 PE=1 SV=1 4.25 3588.3 - 1.64E+06 - - - 3.2372 - 1.688 0.092 - 214.7 2 2 0 0.0045 12 0 0 0 2.72E+06 1.32E+07 - - - 0.9622 1 221125_WJC_METTL3_EV_vs_WT_F02.21147.21147.2 5.57E-07 19/30 K.LYQEVEIASVDAFQGR.E sp|Q92900|RENT1_HUMAN 1 1823.9054 2.07 20091 21147 2 1823.901731 912.96 Regulator of nonsense transcripts 1 OS=Homo sapiens OX=9606 GN=UPF1 PE=1 SV=2 4.14 3588.4 - 1.55E+06 - - - -1.9996 - 3.495 0.612 - 1469.3 1 2 0 -0.0036 16 0 0 0 1.07E+07 5.16E+06 - - - 6.6365 0.9999 221125_WJC_METTL3_EV_vs_WT_F02.21148.21148.3 0.00584 14/48 R.TPFTTSQLLALER.K sp|P35548|MSX2_HUMAN 1 1475.7984 1.3 20092 21148 3 1475.799792 492.9401 Homeobox protein MSX-2 OS=Homo sapiens OX=9606 GN=MSX2 PE=1 SV=3 5.66 3588.5 - 1.42E+06 - - - 0.9473 - 2.525 0.421 - 331.6 1 2 0 0.0014 13 0 0 0 6.06E+06 4.66E+06 - - - 5.7447 0.9967 221125_WJC_METTL3_EV_vs_WT_F02.21150.21150.2 0.0318 12-Jul K.DWNIPFK.Q "sp|Q9BYG3|MK67I_HUMAN,tr|C9J808|C9J808_HUMAN,tr|C9J6C5|C9J6C5_HUMAN" 3 918.46 1.5 20094 21150 2 918.458978 460.2373 MKI67 FHA domain-interacting nucleolar phosphoprotein OS=Homo sapiens OX=9606 GN=NIFK PE=1 SV=1 5.84 3588.7 - 1.10E+06 - - - -1.0616 - 1.429 0.188 - 253.6 1 2 0 -0.001 7 0 0 0 1.07E+07 7.11E+06 - - - 1.5604 0.9769 221125_WJC_METTL3_EV_vs_WT_F02.21152.21152.2 0.0836 Jul-34 K.LSVAC[160.03]FYGGTPYGGQFER.M sp|Q9NR30|DDX21_HUMAN 1 2007.9149 -1 20096 21152 2 2007.910357 1004.9647 Nucleolar RNA helicase 2 OS=Homo sapiens OX=9606 GN=DDX21 PE=1 SV=5 5.99 3589 - 612485 - - - -2.2611 - 1.377 0.117 - 51.4 1 2 0 -0.0045 18 0 0 0 0.00E+00 0.00E+00 - - - 0.6902 0.9981 221125_WJC_METTL3_EV_vs_WT_F02.21154.21154.3 0.011 Nov-56 R.LTEMETLQSQLMAEK.L sp|P35579|MYH9_HUMAN 1 1750.8481 1.27 20097 21154 3 1750.850735 584.6233 Myosin-9 OS=Homo sapiens OX=9606 GN=MYH9 PE=1 SV=4 4.25 3589.2 - 2.28E+06 - - - 1.4918 - 1.687 0.286 - 46.4 1 2 0 0.0026 15 0 0 0 2.63E+07 2.07E+07 - - - 3.0925 0.9999 221125_WJC_METTL3_EV_vs_WT_F02.21159.21159.3 0.000174 Dec-56 R.AILVDLEPGTMDSVR[166.11].S "sp|Q9BVA1|TBB2B_HUMAN,sp|P07437|TBB5_HUMAN,sp|Q13509|TBB3_HUMAN,sp|Q13885|TBB2A_HUMAN,tr|A0A0B4J269|A0A0B4J269_HUMAN,tr|Q5JP53|Q5JP53_HUMAN,tr|G3V3R4|G3V3R4_HUMAN,tr|G3V5W4|G3V5W4_HUMAN,tr|G3V2R8|G3V2R8_HUMAN,tr|G3V2N6|G3V2N6_HUMAN" 10 1624.837 0.68 20101 21159 3 1624.837005 542.6196 Tubulin beta-2B chain OS=Homo sapiens OX=9606 GN=TUBB2B PE=1 SV=1 4.03 3589.5 - 1.05E+07 - - - 0.0166 - 2.457 0.446 - 240.1 1 2 0 0 15 0 0 0 5.90E+07 8.66E+07 - - - 5.8581 1 221125_WJC_METTL3_EV_vs_WT_F02.21160.21160.2 8.76E-09 15/26 R.NEGTATYAAAVLFR.L sp|P14923|PLAK_HUMAN 1 1482.7467 11.52 20102 21160 2 1482.747804 742.3806 Junction plakoglobin OS=Homo sapiens OX=9606 GN=JUP PE=1 SV=3 6 3589.6 - 8.39E+06 - - - 0.7493 - 3.214 0.664 - 1037.8 1 2 0 0.0011 14 0 0 0 9.40E+07 8.16E+06 - - - 6.8748 1 221125_WJC_METTL3_EV_vs_WT_F02.21161.21161.2 5.94E-06 14/28 K.ILQDVADEEIAALPR.D sp|O60783|RT14_HUMAN 1 1651.8781 2.21 20103 21161 2 1651.880231 826.9463 "28S ribosomal protein S14, mitochondrial OS=Homo sapiens OX=9606 GN=MRPS14 PE=1 SV=1" 3.92 3589.6 - 8.18E+06 - - - 1.2894 - 2.809 0.563 - 727.3 1 2 0 0.0021 15 0 0 0 6.95E+07 3.15E+07 - - - 5.7379 0.9998 221125_WJC_METTL3_EV_vs_WT_F02.21162.21162.2 0.00059 16-Aug K.FALNSLLQR.Q "sp|P39880|CUX1_HUMAN,tr|A0A2R8Y852|A0A2R8Y852_HUMAN" 2 1060.6029 1.27 20104 21162 2 1060.603224 531.3087 Homeobox protein cut-like 1 OS=Homo sapiens OX=9606 GN=CUX1 PE=1 SV=3 9.75 3589.6 - 6.61E+06 - - - 0.2781 - 1.9 0.457 - 211 1 2 0 0.0003 9 0 0 0 4.62E+07 3.63E+07 - - - 4.2732 0.9999 221125_WJC_METTL3_EV_vs_WT_F02.21163.21163.2 0.00206 16-Oct K.FALNSLLQR[166.11].Q "sp|P39880|CUX1_HUMAN,tr|A0A2R8Y852|A0A2R8Y852_HUMAN" 2 1070.6112 1.27 20105 21163 2 1070.611365 536.3129 Homeobox protein cut-like 1 OS=Homo sapiens OX=9606 GN=CUX1 PE=1 SV=3 9.75 3589.7 - 5.33E+06 - - - 0.1551 - 2.032 0.487 - 387.4 1 2 0 0.0002 9 0 0 0 4.59E+07 3.63E+07 - - - 4.6892 1 221125_WJC_METTL3_EV_vs_WT_F02.21165.21165.3 3.03E-05 15/56 K.ILQDVADEEIAALPR[166.11].D sp|O60783|RT14_HUMAN 1 1661.8864 2.09 20107 21165 3 1661.88759 554.9694 "28S ribosomal protein S14, mitochondrial OS=Homo sapiens OX=9606 GN=MRPS14 PE=1 SV=1" 3.92 3589.8 - 3.58E+06 - - - 0.7335 - 2.638 0.53 - 272.8 1 2 0 0.0012 15 0 0 0 4.84E+07 2.32E+07 - - - 6.9798 1 221125_WJC_METTL3_EV_vs_WT_F02.21166.21166.3 9.41E-08 14/52 R.NEGTATYAAAVLFR.L sp|P14923|PLAK_HUMAN 1 1482.7467 1.75 20108 21166 3 1482.74858 495.2562 Junction plakoglobin OS=Homo sapiens OX=9606 GN=JUP PE=1 SV=3 6 3589.8 - 2.72E+06 - - - 1.2726 - 2.347 0.627 - 279.3 1 2 0 0.0019 14 0 0 0 4.05E+07 2.31E+07 - - - 7.7971 1 221125_WJC_METTL3_EV_vs_WT_F02.21167.21167.3 0.000647 13/60 K.LYQEVEIASVDAFQGR.E sp|Q92900|RENT1_HUMAN 1 1823.9054 1.72 20109 21167 3 1823.90502 608.9757 Regulator of nonsense transcripts 1 OS=Homo sapiens OX=9606 GN=UPF1 PE=1 SV=2 4.14 3589.9 - 2.50E+06 - - - -0.1963 - 2.659 0.459 - 240.6 1 2 0 -0.0004 16 0 0 0 1.48E+07 8.59E+06 - - - 6.1666 1 221125_WJC_METTL3_EV_vs_WT_F02.21172.21172.3 1.69E-06 20/60 R.QVILQVGVINEAQFSK.A sp|Q08554|DSC1_HUMAN 1 1771.9832 41.15 20114 21172 3 1771.982411 591.6684 Desmocollin-1 OS=Homo sapiens OX=9606 GN=DSC1 PE=1 SV=2 6 3590.4 - 1.77E+06 - - - -0.465 - 3.217 0.534 - 530.8 1 2 0 -0.0008 16 0 0 0 1.49E+07 3.62E+05 - - - 7.4914 0.9996 221125_WJC_METTL3_EV_vs_WT_F02.21173.21173.2 0.000193 26-Dec K.AYSNWPTYPQLYVK.G sp|O76003|GLRX3_HUMAN 1 1728.8512 1.66 20115 21173 2 1728.854382 865.4329 Glutaredoxin-3 OS=Homo sapiens OX=9606 GN=GLRX3 PE=1 SV=2 8.47 3590.5 - 1.53E+06 - - - 1.8648 - 2.006 0.481 - 431.9 1 2 0 0.0032 14 0 0 0 1.85E+07 1.12E+07 - - - 4.3396 0.9998 221125_WJC_METTL3_EV_vs_WT_F02.21174.21174.2 1.68E-05 20/32 K.SMAASGNLGHTPFVDEL.- sp|P22695|QCR2_HUMAN 1 1744.809 - 20116 21174 2 1744.805888 873.4118 "Cytochrome b-c1 complex subunit 2, mitochondrial OS=Homo sapiens OX=9606 GN=UQCRC2 PE=1 SV=3" 4.35 3590.7 - 1.36E+06 - - - -1.8036 - 2.517 0.513 - 197.5 1 2 0 -0.0031 17 0 0 0 - - - - - 5.0984 0.999 221125_WJC_METTL3_EV_vs_WT_F02.21175.21175.2 0.0206 14-Aug R.DLTDYLMK.L "sp|P63261|ACTG_HUMAN,sp|P68133|ACTS_HUMAN,sp|P62736|ACTA_HUMAN,sp|P68032|ACTC_HUMAN,sp|Q562R1|ACTBL_HUMAN,sp|P60709|ACTB_HUMAN,sp|P63267|ACTH_HUMAN,tr|A0A804GS07|A0A804GS07_HUMAN,tr|I3L3I0|I3L3I0_HUMAN,tr|E7EVS6|E7EVS6_HUMAN,tr|A0A6Q8PFE4|A0A6Q8PFE4_HUMAN,tr|I3L1U9|I3L1U9_HUMAN,tr|A0A2R8YEA7|A0A2R8YEA7_HUMAN,tr|A0A804HKV3|A0A804HKV3_HUMAN,tr|A0A2R8Y793|A0A2R8Y793_HUMAN,tr|I3L4N8|I3L4N8_HUMAN,tr|A6NL76|A6NL76_HUMAN" 17 997.479 0.94 20117 21175 2 997.478719 499.7468 "Actin, cytoplasmic 2 OS=Homo sapiens OX=9606 GN=ACTG1 PE=1 SV=1" 4.21 3590.8 - 1.32E+06 - - - -0.3158 - 1.458 0.291 - 185 1 2 0 -0.0003 8 0 0 0 1.99E+08 2.12E+08 - - - 2.3274 0.9941 221125_WJC_METTL3_EV_vs_WT_F02.21177.21177.2 0.0193 14/28 R.IDC[160.03]FSEVPTSVFGEK[136.11].L "sp|O00567|NOP56_HUMAN,tr|A0A494C128|A0A494C128_HUMAN,tr|H0YDU4|H0YDU4_HUMAN,tr|H0Y653|H0Y653_HUMAN" 4 1721.8062 1.31 20118 21177 2 1721.800066 861.9104 Nucleolar protein 56 OS=Homo sapiens OX=9606 GN=NOP56 PE=1 SV=4 4.14 3591.1 - 1.58E+06 - - - -3.5556 - 1.637 0.303 - 112.6 1 2 0 -0.0061 15 0 0 0 1.09E+07 8.35E+06 - - - 2.4888 0.9998 221125_WJC_METTL3_EV_vs_WT_F02.21178.21178.2 0.00142 18-Nov R.VFEYMSYLQR.H "sp|Q9P0T4|ZN581_HUMAN,tr|K7EM32|K7EM32_HUMAN" 2 1334.6329 999 20119 21178 2 1334.633374 668.3237 Zinc finger protein 581 OS=Homo sapiens OX=9606 GN=ZNF581 PE=1 SV=1 5.97 3591.2 - 951256 - - - 0.3484 - 2.121 0.429 - 385.6 1 2 0 0.0005 10 0 0 0 8.00E+06 0.00E+00 - - - 4.3082 0.9999 221125_WJC_METTL3_EV_vs_WT_F02.21179.21179.3 0.00942 15/56 K.ILQDVADEEIAALPR.D sp|O60783|RT14_HUMAN 1 1651.8781 2.11 20120 21179 3 1651.879129 551.6333 "28S ribosomal protein S14, mitochondrial OS=Homo sapiens OX=9606 GN=MRPS14 PE=1 SV=1" 3.92 3591.2 - 8.90E+06 - - - 0.6223 - 2.697 0.378 - 283.2 1 2 0 0.001 15 0 0 0 4.88E+07 2.32E+07 - - - 5.3429 1 221125_WJC_METTL3_EV_vs_WT_F02.21180.21180.3 6.45E-06 14/56 R.AILVDLEPGTMDSVR.S "sp|Q9BVA1|TBB2B_HUMAN,sp|P07437|TBB5_HUMAN,sp|Q13509|TBB3_HUMAN,sp|Q13885|TBB2A_HUMAN,tr|A0A0B4J269|A0A0B4J269_HUMAN,tr|Q5JP53|Q5JP53_HUMAN,tr|G3V3R4|G3V3R4_HUMAN,tr|G3V5W4|G3V5W4_HUMAN,tr|G3V2R8|G3V2R8_HUMAN,tr|G3V2N6|G3V2N6_HUMAN" 10 1614.8287 0.68 20121 21180 3 1614.830332 539.2835 Tubulin beta-2B chain OS=Homo sapiens OX=9606 GN=TUBB2B PE=1 SV=1 4.03 3591.3 - 8.69E+06 - - - 1.0057 - 2.797 0.534 - 329.2 1 2 0 0.0016 15 0 0 0 5.90E+07 8.66E+07 - - - 7.177 0.9991 221125_WJC_METTL3_EV_vs_WT_F02.21182.21182.2 0.0114 14-Aug R.DLTDYLMK[136.11].L "sp|P63261|ACTG_HUMAN,sp|P68133|ACTS_HUMAN,sp|P62736|ACTA_HUMAN,sp|P68032|ACTC_HUMAN,sp|Q562R1|ACTBL_HUMAN,sp|P60709|ACTB_HUMAN,sp|P63267|ACTH_HUMAN,tr|A0A804GS07|A0A804GS07_HUMAN,tr|I3L3I0|I3L3I0_HUMAN,tr|E7EVS6|E7EVS6_HUMAN,tr|A0A6Q8PFE4|A0A6Q8PFE4_HUMAN,tr|I3L1U9|I3L1U9_HUMAN,tr|A0A2R8YEA7|A0A2R8YEA7_HUMAN,tr|A0A804HKV3|A0A804HKV3_HUMAN,tr|A0A2R8Y793|A0A2R8Y793_HUMAN,tr|I3L4N8|I3L4N8_HUMAN,tr|A6NL76|A6NL76_HUMAN" 17 1005.4932 0.94 20123 21182 2 1005.493153 503.7539 "Actin, cytoplasmic 2 OS=Homo sapiens OX=9606 GN=ACTG1 PE=1 SV=1" 4.21 3591.3 - 5.04E+06 - - - -0.0806 - 1.471 0.301 - 185.3 1 2 0 -0.0001 8 0 0 0 1.99E+08 2.12E+08 - - - 2.4281 0.9944 221125_WJC_METTL3_EV_vs_WT_F02.21183.21183.2 0.219 24-Sep K.DFTATDLSEFAAK.A "sp|P42765|THIM_HUMAN,tr|A0A0B4J2A4|A0A0B4J2A4_HUMAN" 2 1414.6616 7.52 20124 21183 2 1414.661088 708.3381 "3-ketoacyl-CoA thiolase, mitochondrial OS=Homo sapiens OX=9606 GN=ACAA2 PE=1 SV=2" 4.03 3591.4 - 4.04E+06 - - - -0.3803 - 1.268 0.187 - 109.9 1 2 0 -0.0005 13 0 0 0 2.74E+07 3.65E+06 - - - 1.0314 0.9999 221125_WJC_METTL3_EV_vs_WT_F02.21189.21189.3 1.12E-05 15/60 K.LYQEVEIASVDAFQGR[166.11].E sp|Q92900|RENT1_HUMAN 1 1833.9136 1.72 20130 21189 3 1833.914848 612.3118 Regulator of nonsense transcripts 1 OS=Homo sapiens OX=9606 GN=UPF1 PE=1 SV=2 4.14 3592.1 - 1.16E+06 - - - 0.6543 - 2.899 0.338 - 282.8 1 2 0 0.0012 16 0 0 0 1.48E+07 8.59E+06 - - - 5.0391 0.9996 221125_WJC_METTL3_EV_vs_WT_F02.21191.21191.2 7.24E-05 13/22 K.ELSVMFIETSAK[136.11].T sp|Q9NRW1|RAB6B_HUMAN 1 1361.6992 2.59 20132 21191 2 1361.698678 681.8569 Ras-related protein Rab-6B OS=Homo sapiens OX=9606 GN=RAB6B PE=1 SV=1 4.53 3592.3 - 619259 - - - -0.3863 - 1.794 0.362 - 409 1 2 0 -0.0005 12 0 0 0 1.25E+07 4.84E+06 - - - 3.2523 0.9997 221125_WJC_METTL3_EV_vs_WT_F02.21195.21195.2 0.00367 16-Oct R.APFDLFENR[166.11].K sp|P07900|HS90A_HUMAN 1 1117.5432 0.64 20134 21195 2 1117.544664 559.7789 Heat shock protein HSP 90-alpha OS=Homo sapiens OX=9606 GN=HSP90AA1 PE=1 SV=5 4.37 3592.8 - 2.77E+06 - - - 1.3288 - 2.061 0.422 - 413.2 1 2 0 0.0015 9 0 0 0 1.33E+07 2.08E+07 - - - 4.2497 1 221125_WJC_METTL3_EV_vs_WT_F02.21196.21196.3 3.83E-08 15/52 K.LNLVDLAGSENIGR.S "sp|P52732|KIF11_HUMAN,tr|A0A7I2YQY4|A0A7I2YQY4_HUMAN,tr|A0A7I2V3A9|A0A7I2V3A9_HUMAN,tr|A0A7I2V3V3|A0A7I2V3V3_HUMAN" 4 1469.7838 5.2 20135 21196 3 1469.784241 490.9352 Kinesin-like protein KIF11 OS=Homo sapiens OX=9606 GN=KIF11 PE=1 SV=2 4.37 3592.8 - 3.07E+06 - - - 0.2953 - 3.28 0.551 - 400.6 1 2 0 0.0004 14 0 0 0 2.05E+08 3.95E+07 - - - 7.8397 0.9999 221125_WJC_METTL3_EV_vs_WT_F02.21197.21197.2 2.97E-05 14/28 K.VVVQVLAEEPEAVLK[136.11].G "sp|P49327|FAS_HUMAN,tr|A0A0U1RQF0|A0A0U1RQF0_HUMAN" 2 1629.9433 2.36 20136 21197 2 1629.942602 815.9789 Fatty acid synthase OS=Homo sapiens OX=9606 GN=FASN PE=1 SV=3 4.25 3592.9 - 5.30E+06 - - - -0.4123 - 2.457 0.469 - 592.9 1 2 0 -0.0007 15 0 0 0 8.82E+07 3.73E+07 - - - 4.7149 1 221125_WJC_METTL3_EV_vs_WT_F02.21201.21201.2 1.16E-07 20/30 K.LFIGGLNVQTSESGLR.G sp|Q13151|ROA0_HUMAN 1 1689.905 1.26 20140 21201 2 1689.905741 845.9598 Heterogeneous nuclear ribonucleoprotein A0 OS=Homo sapiens OX=9606 GN=HNRNPA0 PE=1 SV=1 6 3593.4 - 1.82E+06 - - - 0.448 - 3.603 0.614 - 1383.4 1 2 0 0.0008 16 0 0 0 1.00E+08 7.94E+07 - - - 6.727 1 221125_WJC_METTL3_EV_vs_WT_F02.21202.21202.2 0.000399 16/32 R.EGPYSISVLYGDEEVPR[166.11].S "sp|P21333|FLNA_HUMAN,tr|Q60FE5|Q60FE5_HUMAN" 2 1918.9188 0.84 20141 21202 2 1918.915766 960.4667 Filamin-A OS=Homo sapiens OX=9606 GN=FLNA PE=1 SV=4 4 3593.5 - 1.71E+06 - - - -1.5775 - 2.986 0.64 - 780.1 1 2 0 -0.003 17 0 0 0 8.94E+06 1.06E+07 - - - 6.4566 1 221125_WJC_METTL3_EV_vs_WT_F02.21203.21203.2 2.01E-09 21/30 R.QAQIEVVPSASALIIK[136.11].A sp|P30050|RL12_HUMAN 1 1673.9807 1.49 20142 21203 2 1673.982438 837.9976 60S ribosomal protein L12 OS=Homo sapiens OX=9606 GN=RPL12 PE=1 SV=1 6 3593.6 - 1.54E+06 - - - 1.0251 - 3.35 0.528 - 1373.2 1 2 0 0.0017 16 0 0 0 5.72E+08 3.83E+08 - - - 5.9126 1 221125_WJC_METTL3_EV_vs_WT_F02.21204.21204.2 4.57E-09 19/30 K.LFIGGLNVQTSESGLR[166.11].G sp|Q13151|ROA0_HUMAN 1 1699.9133 1.26 20143 21204 2 1699.91401 850.9639 Heterogeneous nuclear ribonucleoprotein A0 OS=Homo sapiens OX=9606 GN=HNRNPA0 PE=1 SV=1 6 3593.7 - 1.38E+06 - - - 0.4447 - 3.615 0.6 - 1175.6 1 2 0 0.0008 16 0 0 0 1.00E+08 7.94E+07 - - - 6.6318 1 221125_WJC_METTL3_EV_vs_WT_F02.21205.21205.2 2.69E-06 17/30 R.QVILQVGVINEAQFSK.A sp|Q08554|DSC1_HUMAN 1 1771.9832 999 20144 21205 2 1771.98592 886.9989 Desmocollin-1 OS=Homo sapiens OX=9606 GN=DSC1 PE=1 SV=2 6 3593.9 - 1.29E+06 - - - 1.5153 - 3.553 0.596 - 928.7 1 2 0 0.0027 16 0 0 0 1.72E+07 0.00E+00 - - - 6.5591 1 221125_WJC_METTL3_EV_vs_WT_F02.21207.21207.2 1.13E-06 15/32 K.IVSVGDDQEIHIYDC[160.03]PI.- "sp|Q9GZS3|WDR61_HUMAN,tr|H0YL19|H0YL19_HUMAN" 2 1971.9248 - 20146 21207 2 1971.928207 986.9697 WD repeat-containing protein 61 OS=Homo sapiens OX=9606 GN=WDR61 PE=1 SV=1 3.84 3594.2 - 1.02E+06 - - - 1.7308 - 2.853 0.639 - 304.7 1 2 0 0.0034 17 0 0 0 - - - - - 6.3371 1 221125_WJC_METTL3_EV_vs_WT_F02.21208.21208.2 2.22E-09 14/26 K.AYSNWPTYPQLYVK[136.11].G sp|O76003|GLRX3_HUMAN 1 1736.8654 1.66 20147 21208 2 1736.869402 869.44 Glutaredoxin-3 OS=Homo sapiens OX=9606 GN=GLRX3 PE=1 SV=2 8.47 3594.3 - 940700 - - - 2.3283 - 2.681 0.631 - 609.2 1 2 0 0.004 14 0 0 0 1.85E+07 1.12E+07 - - - 6.1751 1 221125_WJC_METTL3_EV_vs_WT_F02.21209.21209.2 1.61E-05 18/30 K.VQLVGLDEESSEFIC[160.03]R.N sp|P61962|DCAF7_HUMAN 1 1879.8986 1.25 20148 21209 2 1879.90136 940.9566 DDB1- and CUL4-associated factor 7 OS=Homo sapiens OX=9606 GN=DCAF7 PE=1 SV=1 4 3594.4 - 643760 - - - 1.4793 - 3.233 0.613 - 834.4 1 2 0 0.0028 16 0 0 0 4.78E+07 3.83E+07 - - - 6.4526 0.9997 221125_WJC_METTL3_EV_vs_WT_F02.21212.21212.2 3.39E-07 Sep-32 R.IFC[160.03]GDLGNEVNDDILAR[166.11].A "sp|Q9BTD8|RBM42_HUMAN,tr|K7EQ03|K7EQ03_HUMAN,tr|K7EP90|K7EP90_HUMAN" 3 1929.913 2.12 20151 21212 2 1929.916112 965.9638 RNA-binding protein 42 OS=Homo sapiens OX=9606 GN=RBM42 PE=1 SV=1 3.84 3594.8 - 492599 - - - 1.6141 - 1.915 0.534 - 168.7 1 2 0 0.0031 17 0 0 0 1.26E+07 5.92E+06 - - - 4.5815 0.9999 221125_WJC_METTL3_EV_vs_WT_F02.21213.21213.3 3.88E-06 Oct-36 R.RIPILFFANK.M "sp|Q9H0F7|ARL6_HUMAN,tr|A0A0J9YXT0|A0A0J9YXT0_HUMAN,tr|H7C5H6|H7C5H6_HUMAN" 3 1217.7285 1.52 20152 21213 3 1217.729536 406.9168 ADP-ribosylation factor-like protein 6 OS=Homo sapiens OX=9606 GN=ARL6 PE=1 SV=1 11 3594.9 - 461861 - - - 0.8803 - 2.074 0.469 - 151 1 2 0 0.0011 10 0 0 0 2.92E+06 1.92E+06 - - - 5.899 1 221125_WJC_METTL3_EV_vs_WT_F02.21218.21218.2 4.40E-07 16/30 R.QAQIEVVPSASALIIK.A sp|P30050|RL12_HUMAN 1 1665.9665 1.49 20155 21218 2 1665.96659 833.9905 60S ribosomal protein L12 OS=Homo sapiens OX=9606 GN=RPL12 PE=1 SV=1 6 3595.5 - 2.21E+07 - - - 0.0408 - 3.04 0.63 - 649 1 2 0 0.0001 16 0 0 0 5.72E+08 3.83E+08 - - - 6.4277 0.9997 221125_WJC_METTL3_EV_vs_WT_F02.21220.21220.2 0.00381 18-Sep K.FAAQELIEVK[136.11].R "sp|Q86U44|MTA70_HUMAN,tr|F5H6D8|F5H6D8_HUMAN,tr|H0YFV6|H0YFV6_HUMAN,tr|B4DTN4|B4DTN4_HUMAN" 4 1154.6427 0.001 20157 21220 2 1154.642634 578.3286 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 4.53 3595.6 - 8.27E+06 - - - -0.0355 - 1.671 0.411 - 209.7 1 2 0 0 10 0 0 0 0.00E+00 9.26E+07 - - - 3.5098 0.9999 221125_WJC_METTL3_EV_vs_WT_F02.21221.21221.2 2.87E-06 22-Dec K.NIEDVIAQGIGK.L "sp|P05387|RLA2_HUMAN,tr|H0YDD8|H0YDD8_HUMAN" 2 1255.6772 1.25 20158 21221 2 1255.677323 628.8459 60S acidic ribosomal protein P2 OS=Homo sapiens OX=9606 GN=RPLP2 PE=1 SV=1 4.37 3595.6 - 6.17E+06 - - - 0.0852 - 2.177 0.502 - 307.1 1 2 0 0.0001 12 0 0 0 3.99E+08 3.19E+08 - - - 4.7957 0.9999 221125_WJC_METTL3_EV_vs_WT_F02.21222.21222.2 2.79E-07 22-Dec R.YSLTYIYTGLSK.H "sp|P25311|ZA2G_HUMAN,tr|C9JEV0|C9JEV0_HUMAN" 2 1407.7286 157.29 20159 21222 2 1407.72885 704.8716 Zinc-alpha-2-glycoprotein OS=Homo sapiens OX=9606 GN=AZGP1 PE=1 SV=2 8.43 3595.7 - 5.67E+06 - - - 0.1897 - 2.378 0.537 - 379.1 1 2 0 0.0003 12 0 0 0 1.34E+08 8.54E+05 - - - 5.2865 0.9999 221125_WJC_METTL3_EV_vs_WT_F02.21223.21223.2 3.01E-05 22-Nov K.NIEDVIAQGIGK[136.11].L "sp|P05387|RLA2_HUMAN,tr|H0YDD8|H0YDD8_HUMAN" 2 1263.6914 1.25 20160 21223 2 1263.690959 632.853 60S acidic ribosomal protein P2 OS=Homo sapiens OX=9606 GN=RPLP2 PE=1 SV=1 4.37 3595.7 - 5.28E+06 - - - -0.3616 - 2.204 0.553 - 270.9 1 2 0 -0.0005 12 0 0 0 3.99E+08 3.19E+08 - - - 5.2047 1 221125_WJC_METTL3_EV_vs_WT_F02.21226.21226.2 3.32E-06 15/28 R.EALLGVQEDVDEYVK[136.11].L "sp|Q14257|RCN2_HUMAN,tr|H0YL43|H0YL43_HUMAN" 2 1713.8552 1.1 20163 21226 2 1713.860695 857.9349 Reticulocalbin-2 OS=Homo sapiens OX=9606 GN=RCN2 PE=1 SV=1 3.83 3595.9 - 2.60E+06 - - - 3.1788 - 2.917 0.607 - 697.1 1 2 0 0.0054 15 0 0 0 4.15E+07 3.78E+07 - - - 6.1546 0.9998 221125_WJC_METTL3_EV_vs_WT_F02.21227.21227.2 1.83E-06 28-Oct R.LVPTGLDFGQEGFTR.F sp|P46087|NOP2_HUMAN 1 1635.8257 1 20164 21227 2 1635.826396 818.9201 Probable 28S rRNA (cytosine(4447)-C(5))-methyltransferase OS=Homo sapiens OX=9606 GN=NOP2 PE=1 SV=2 4.37 3595.9 - 2.23E+06 - - - 0.4432 - 2.047 0.513 - 236.9 1 2 0 0.0007 15 0 0 0 1.50E+07 1.51E+07 - - - 4.591 0.9992 221125_WJC_METTL3_EV_vs_WT_F02.21229.21229.2 0.000878 22-Oct K.NSIPEPIDPLFK.H "sp|P0DJD0|RGPD1_HUMAN,sp|Q7Z3J3|RGPD4_HUMAN,sp|O14715|RGPD8_HUMAN,sp|P49792|RBP2_HUMAN,sp|P0DJD1|RGPD2_HUMAN,sp|A6NKT7|RGPD3_HUMAN,sp|Q99666|RGPD5_HUMAN,tr|F8W705|F8W705_HUMAN,tr|A0A286YES2|A0A286YES2_HUMAN,tr|F8VYC4|F8VYC4_HUMAN,tr|J3KNE0|J3KNE0_HUMAN,tr|A0A1W2PNU4|A0A1W2PNU4_HUMAN,tr|J3KQ37|J3KQ37_HUMAN" 13 1368.7289 1.06 20166 21229 2 1368.728761 685.3717 RANBP2-like and GRIP domain-containing protein 1 OS=Homo sapiens OX=9606 GN=RGPD1 PE=2 SV=1 4.37 3596.1 - 1.83E+06 - - - -0.114 - 1.944 0.236 - 382.7 1 2 0 -0.0002 12 0 0 0 1.24E+07 1.17E+07 - - - 2.5331 0.9992 221125_WJC_METTL3_EV_vs_WT_F02.21231.21231.2 0.000551 22-Sep K.NSIPEPIDPLFK[136.11].H "sp|P0DJD0|RGPD1_HUMAN,sp|Q7Z3J3|RGPD4_HUMAN,sp|O14715|RGPD8_HUMAN,sp|P49792|RBP2_HUMAN,sp|P0DJD1|RGPD2_HUMAN,sp|A6NKT7|RGPD3_HUMAN,sp|Q99666|RGPD5_HUMAN,tr|F8W705|F8W705_HUMAN,tr|A0A286YES2|A0A286YES2_HUMAN,tr|F8VYC4|F8VYC4_HUMAN,tr|J3KNE0|J3KNE0_HUMAN,tr|A0A1W2PNU4|A0A1W2PNU4_HUMAN,tr|J3KQ37|J3KQ37_HUMAN" 13 1376.7431 1.14 20168 21231 2 1376.744499 689.3788 RANBP2-like and GRIP domain-containing protein 1 OS=Homo sapiens OX=9606 GN=RGPD1 PE=2 SV=1 4.37 3596.3 - 1.59E+06 - - - 1.0038 - 1.948 0.275 - 298 1 2 0 0.0014 12 0 0 0 1.24E+07 1.08E+07 - - - 2.8262 0.9999 221125_WJC_METTL3_EV_vs_WT_F02.21232.21232.2 1.17E-06 16-Oct R.DDEYDYLFK[136.11].V "sp|Q15907|RB11B_HUMAN,sp|P62491|RB11A_HUMAN,tr|B4DQU5|B4DQU5_HUMAN,tr|H3BMH2|H3BMH2_HUMAN,tr|H3BSC1|H3BSC1_HUMAN" 5 1214.5223 2.57 20169 21232 2 1214.522314 608.2684 Ras-related protein Rab-11B OS=Homo sapiens OX=9606 GN=RAB11B PE=1 SV=4 3.84 3596.4 - 1.46E+06 - - - 0.0239 - 2.083 0.572 - 456.3 1 2 0 0 9 0 0 0 2.87E+07 1.12E+07 - - - 5.3887 1 221125_WJC_METTL3_EV_vs_WT_F02.21234.21234.3 8.57E-09 20/48 R.FTAR[166.11]PLVETIFER[166.11].G "sp|O00139|KIF2A_HUMAN,tr|D6R9M0|D6R9M0_HUMAN,tr|A0A6Q8PFA6|A0A6Q8PFA6_HUMAN,tr|A0A6Q8PGG1|A0A6Q8PGG1_HUMAN,tr|A0A6Q8PGH7|A0A6Q8PGH7_HUMAN,tr|A0A6Q8PG37|A0A6Q8PG37_HUMAN,tr|A0A6Q8PH57|A0A6Q8PH57_HUMAN" 7 1597.8731 1.3 20171 21234 3 1597.871254 533.6316 Kinesin-like protein KIF2A OS=Homo sapiens OX=9606 GN=KIF2A PE=1 SV=3 6.14 3596.7 - 868786 - - - -1.1666 - 3.298 0.551 - 402.1 1 2 0 -0.0019 13 0 0 0 1.06E+07 8.20E+06 - - - 7.918 0.9995 221125_WJC_METTL3_EV_vs_WT_F02.21235.21235.2 1.55E-05 20-Nov R.ATFYLNVLQQR[166.11].Q sp|Q9UBF2|COPG2_HUMAN 1 1361.7331 0.25 20172 21235 2 1361.73017 681.8738 Coatomer subunit gamma-2 OS=Homo sapiens OX=9606 GN=COPG2 PE=1 SV=1 8.79 3596.8 - 811871 - - - -2.1553 - 2.151 0.414 - 361 1 2 0 -0.0029 11 0 0 0 1.23E+06 4.85E+06 - - - 4.1699 1 221125_WJC_METTL3_EV_vs_WT_F02.21237.21237.3 8.92E-06 14/44 K.K[136.11]PGGFDISLFYR[166.11].D "sp|P12956|XRCC6_HUMAN,tr|B1AHC9|B1AHC9_HUMAN" 2 1416.7521 1.01 20174 21237 3 1416.751677 473.258 X-ray repair cross-complementing protein 6 OS=Homo sapiens OX=9606 GN=XRCC6 PE=1 SV=2 8.59 3597.1 - 504229 - - - -0.2675 - 2.626 0.447 - 365.8 1 2 0 -0.0004 12 0 0 0 1.20E+07 1.19E+07 - - - 6.1996 1 221125_WJC_METTL3_EV_vs_WT_F02.21242.21242.2 7.98E-08 24-Nov K.FNADEFEDMVAEK.R "sp|P27635|RL10_HUMAN,tr|F8W7C6|F8W7C6_HUMAN,tr|X1WI28|X1WI28_HUMAN" 3 1543.6501 0.97 20177 21242 2 1543.648682 772.8323 60S ribosomal protein L10 OS=Homo sapiens OX=9606 GN=RPL10 PE=1 SV=4 3.83 3597.6 - 3.03E+06 - - - -0.9024 - 2.507 0.611 - 255 1 2 0 -0.0014 13 0 0 0 3.65E+07 3.76E+07 - - - 5.9123 1 221125_WJC_METTL3_EV_vs_WT_F02.21243.21243.2 9.83E-09 15/24 K.FNADEFEDMVAEK[136.11].R "sp|P27635|RL10_HUMAN,tr|F8W7C6|F8W7C6_HUMAN,tr|X1WI28|X1WI28_HUMAN" 3 1551.6643 0.97 20178 21243 2 1551.661919 776.8394 60S ribosomal protein L10 OS=Homo sapiens OX=9606 GN=RPL10 PE=1 SV=4 3.83 3597.7 - 2.72E+06 - - - -1.5184 - 3.094 0.639 - 592.4 1 2 0 -0.0024 13 0 0 0 3.65E+07 3.76E+07 - - - 6.6587 0.9998 221125_WJC_METTL3_EV_vs_WT_F02.21244.21244.3 5.18E-05 Nov-60 K.LFIGGLNVQTSESGLR.G sp|Q13151|ROA0_HUMAN 1 1689.905 1.14 20179 21244 3 1689.908124 564.3089 Heterogeneous nuclear ribonucleoprotein A0 OS=Homo sapiens OX=9606 GN=HNRNPA0 PE=1 SV=1 6 3597.8 - 2.62E+06 - - - 1.8581 - 2.049 0.423 - 119.9 1 2 0 0.0031 16 0 0 0 1.63E+07 1.43E+07 - - - 5.0958 0.9999 221125_WJC_METTL3_EV_vs_WT_F02.21245.21245.3 3.02E-05 Dec-60 K.LFIGGLNVQTSESGLR[166.11].G sp|Q13151|ROA0_HUMAN 1 1699.9133 1.14 20180 21245 3 1699.90963 567.645 Heterogeneous nuclear ribonucleoprotein A0 OS=Homo sapiens OX=9606 GN=HNRNPA0 PE=1 SV=1 6 3597.9 - 2.30E+06 - - - -2.1319 - 2.212 0.464 - 157.6 1 2 0 -0.0036 16 0 0 0 1.63E+07 1.43E+07 - - - 5.7492 1 221125_WJC_METTL3_EV_vs_WT_F02.21246.21246.2 2.57E-06 16-Aug R.DDEYDYLFK.V "sp|Q15907|RB11B_HUMAN,sp|P62491|RB11A_HUMAN,tr|B4DQU5|B4DQU5_HUMAN,tr|H3BMH2|H3BMH2_HUMAN,tr|H3BSC1|H3BSC1_HUMAN" 5 1206.5081 2.96 20181 21246 2 1206.509349 604.2613 Ras-related protein Rab-11B OS=Homo sapiens OX=9606 GN=RAB11B PE=1 SV=4 3.84 3597.9 - 2.21E+06 - - - 1.0477 - 1.93 0.651 - 238.4 1 2 0 0.0013 9 0 0 0 3.31E+07 1.12E+07 - - - 5.7511 0.9958 221125_WJC_METTL3_EV_vs_WT_F02.21248.21248.3 0.0684 Oct-56 R.GLIVYQLENQPSEFR[166.11].R "sp|P78406|RAE1L_HUMAN,tr|E9PQ57|E9PQ57_HUMAN,tr|E9PPG9|E9PPG9_HUMAN" 3 1801.9238 1.97 20183 21248 3 1801.918969 601.6485 mRNA export factor OS=Homo sapiens OX=9606 GN=RAE1 PE=1 SV=1 4.53 3598.1 - 1.83E+06 - - - -2.6916 - 1.938 0.251 - 119.7 1 2 0 -0.0049 15 0 0 0 1.08E+08 5.47E+07 - - - 3.0636 0.9999 221125_WJC_METTL3_EV_vs_WT_F02.21249.21249.2 9.44E-06 14/22 K.SLESLDTSLFAK[136.11].N sp|Q12874|SF3A3_HUMAN 1 1317.6907 3.6 20184 21249 2 1317.690378 659.8527 Splicing factor 3A subunit 3 OS=Homo sapiens OX=9606 GN=SF3A3 PE=1 SV=1 4.37 3598.2 - 1.63E+06 - - - -0.2808 - 2.82 0.517 - 443.6 1 2 0 -0.0004 12 0 0 0 2.91E+08 8.09E+07 - - - 5.5873 0.9999 221125_WJC_METTL3_EV_vs_WT_F02.21251.21251.2 0.000925 18-Nov K.SQEQILEILR[166.11].F sp|P12270|TPR_HUMAN 1 1237.6906 2.57 20186 21251 2 1237.690184 619.8526 Nucleoprotein TPR OS=Homo sapiens OX=9606 GN=TPR PE=1 SV=3 4.53 3598.4 - 1.59E+06 - - - -0.3135 - 2.418 0.448 - 636.2 1 2 0 -0.0004 10 0 0 0 4.50E+07 1.75E+07 - - - 4.8144 1 221125_WJC_METTL3_EV_vs_WT_F02.21252.21252.3 3.66E-07 17/44 K.KPGGFDISLFYR.D "sp|P12956|XRCC6_HUMAN,tr|B1AHC9|B1AHC9_HUMAN" 2 1398.7296 1.01 20187 21252 3 1398.73092 467.2505 X-ray repair cross-complementing protein 6 OS=Homo sapiens OX=9606 GN=XRCC6 PE=1 SV=2 8.59 3598.6 - 1.26E+06 - - - 0.9537 - 2.886 0.549 - 564.8 1 2 0 0.0013 12 0 0 0 1.20E+07 1.19E+07 - - - 7.5982 1 221125_WJC_METTL3_EV_vs_WT_F02.21253.21253.3 0.000174 15/44 K.NIEDVIAQGIGK.L "sp|P05387|RLA2_HUMAN,tr|H0YDD8|H0YDD8_HUMAN" 2 1255.6772 1.23 20188 21253 3 1255.676477 419.5663 60S acidic ribosomal protein P2 OS=Homo sapiens OX=9606 GN=RPLP2 PE=1 SV=1 4.37 3598.7 - 1.25E+06 - - - -0.5885 - 2.479 0.443 - 402.4 1 2 0 -0.0007 12 0 0 0 1.94E+07 1.58E+07 - - - 5.9952 1 221125_WJC_METTL3_EV_vs_WT_F02.21254.21254.3 4.91E-06 16/68 R.VFAFDATAR[166.11]PPGYEFELK[136.11].L sp|Q8IU81|I2BP1_HUMAN 1 2075.0483 1.22 20189 21254 3 2075.04774 692.69 Interferon regulatory factor 2-binding protein 1 OS=Homo sapiens OX=9606 GN=IRF2BP1 PE=1 SV=1 4.68 3598.8 - 1.22E+06 - - - -0.2689 - 2.795 0.478 - 205.7 1 2 0 -0.0006 18 0 0 0 1.57E+07 1.29E+07 - - - 6.4285 0.9992 221125_WJC_METTL3_EV_vs_WT_F02.21255.21255.3 0.00213 Dec-44 R.YSLTYIYTGLSK.H "sp|P25311|ZA2G_HUMAN,tr|C9JEV0|C9JEV0_HUMAN" 2 1407.7286 1.69 20190 21255 3 1407.729705 470.2501 Zinc-alpha-2-glycoprotein OS=Homo sapiens OX=9606 GN=AZGP1 PE=1 SV=2 8.43 3598.9 - 1.14E+06 - - - 0.797 - 1.863 0.292 - 138.5 1 2 0 0.0011 12 0 0 0 7.70E+06 4.57E+06 - - - 3.5198 0.9997 221125_WJC_METTL3_EV_vs_WT_F02.21257.21257.3 8.61E-05 Nov-32 K.LK[136.11]LEDFFAR[166.11].N "sp|P11413|G6PD_HUMAN,tr|E7EM57|E7EM57_HUMAN,tr|E9PD92|E9PD92_HUMAN,tr|E7EUI8|E7EUI8_HUMAN" 4 1155.6407 0.12 20192 21257 3 1155.639554 386.2208 Glucose-6-phosphate 1-dehydrogenase OS=Homo sapiens OX=9606 GN=G6PD PE=1 SV=4 6.07 3599.2 - 878037 - - - -1.0046 - 2.388 0.397 - 151.4 1 2 1 -0.0012 9 0 0 0 6.03E+05 4.92E+06 - - - 5.5892 1 221125_WJC_METTL3_EV_vs_WT_F02.21258.21258.2 4.41E-05 Nov-32 R.EGPYSISVLYGDEEVPR.S "sp|P21333|FLNA_HUMAN,tr|Q60FE5|Q60FE5_HUMAN" 2 1908.9105 0.84 20193 21258 2 1908.902674 955.4625 Filamin-A OS=Homo sapiens OX=9606 GN=FLNA PE=1 SV=4 4 3599.3 - 684983 - - - -4.1118 - 2.443 0.646 - 367.4 1 2 0 -0.0078 17 0 0 0 8.94E+06 1.06E+07 - - - 6.0059 0.9999 221125_WJC_METTL3_EV_vs_WT_F02.21261.21261.2 1.26E-05 13/22 K.SLESLDTSLFAK.N sp|Q12874|SF3A3_HUMAN 1 1309.6765 3.63 20195 21261 2 1309.675221 655.8456 Splicing factor 3A subunit 3 OS=Homo sapiens OX=9606 GN=SF3A3 PE=1 SV=1 4.37 3599.7 - 2.74E+07 - - - -1.0132 - 2.709 0.494 - 427.1 1 2 0 -0.0013 12 0 0 0 2.92E+08 8.04E+07 - - - 5.3114 0.9998 221125_WJC_METTL3_EV_vs_WT_F02.21263.21263.2 0.00454 16-Oct R.DAETWFLSK.T "sp|P08779|K1C16_HUMAN,tr|K7ENW6|K7ENW6_HUMAN" 2 1095.5237 13947.27 20196 21263 2 1095.523824 548.7691 "Keratin, type I cytoskeletal 16 OS=Homo sapiens OX=9606 GN=KRT16 PE=1 SV=4" 4.37 3599.9 - 1.41E+07 - - - 0.1351 - 2.008 0.387 - 386.3 1 2 0 0.0001 9 0 0 0 3.96E+09 2.84E+05 - - - 3.9162 0.9998 221125_WJC_METTL3_EV_vs_WT_F02.21264.21264.2 6.92E-05 18-Dec K.SQEQILEILR.F sp|P12270|TPR_HUMAN 1 1227.6823 2.57 20197 21264 2 1227.683051 614.8484 Nucleoprotein TPR OS=Homo sapiens OX=9606 GN=TPR PE=1 SV=3 4.53 3599.9 - 8.13E+06 - - - 0.6101 - 2.534 0.385 - 813 1 2 0 0.0008 10 0 0 0 4.50E+07 1.75E+07 - - - 4.4797 1 221125_WJC_METTL3_EV_vs_WT_F02.21265.21265.3 5.55E-07 15/60 R.QAQIEVVPSASALIIK[136.11].A sp|P30050|RL12_HUMAN 1 1673.9807 1.52 20198 21265 3 1673.981451 559.0009 60S ribosomal protein L12 OS=Homo sapiens OX=9606 GN=RPL12 PE=1 SV=1 6 3599.9 - 2.57E+07 - - - 0.4355 - 3.005 0.547 - 393.8 1 2 0 0.0007 16 0 0 0 2.51E+08 1.65E+08 - - - 7.4615 0.9999 221125_WJC_METTL3_EV_vs_WT_F02.21266.21266.2 7.33E-07 13/22 K.TIEDLATQLNLK.T "sp|P39880|CUX1_HUMAN,tr|A0A2R8Y852|A0A2R8Y852_HUMAN,tr|A0A2R8YDI1|A0A2R8YDI1_HUMAN" 3 1357.7453 1.47 20199 21266 2 1357.745201 679.8799 Homeobox protein cut-like 1 OS=Homo sapiens OX=9606 GN=CUX1 PE=1 SV=3 4.37 3600 - 7.95E+06 - - - -0.07 - 2.592 0.462 - 342 1 2 0 -0.0001 12 0 0 0 6.18E+07 4.20E+07 - - - 4.9593 0.9998 221125_WJC_METTL3_EV_vs_WT_F02.21269.21269.3 0.000343 Dec-44 K.NIEDVIAQGIGK[136.11].L "sp|P05387|RLA2_HUMAN,tr|H0YDD8|H0YDD8_HUMAN" 2 1263.6914 1.23 20202 21269 3 1263.690923 422.2377 60S acidic ribosomal protein P2 OS=Homo sapiens OX=9606 GN=RPLP2 PE=1 SV=1 4.37 3600.2 - 2.89E+06 - - - -0.3901 - 1.94 0.382 - 282.6 1 2 0 -0.0005 12 0 0 0 1.94E+07 1.58E+07 - - - 4.6357 1 221125_WJC_METTL3_EV_vs_WT_F02.21270.21270.3 6.22E-06 21/52 R.LAAAWDALIVR[166.11]PVR[166.11].R "sp|Q9BRR6|ADPGK_HUMAN,tr|H3BRS6|H3BRS6_HUMAN,tr|H3BTH4|H3BTH4_HUMAN,tr|H3BN66|H3BN66_HUMAN" 4 1569.9258 0.99 20203 21270 3 1569.927438 524.3159 ADP-dependent glucokinase OS=Homo sapiens OX=9606 GN=ADPGK PE=1 SV=1 9.6 3600.2 - 2.50E+06 - - - 1.0293 - 3.163 0.454 - 798 1 2 0 0.0016 14 0 0 0 1.66E+07 1.68E+07 - - - 6.6614 1 221125_WJC_METTL3_EV_vs_WT_F02.21271.21271.3 8.47E-06 17/52 R.LAAAWDALIVRPVR.R "sp|Q9BRR6|ADPGK_HUMAN,tr|H3BRS6|H3BRS6_HUMAN,tr|H3BTH4|H3BTH4_HUMAN,tr|H3BN66|H3BN66_HUMAN" 4 1549.9093 0.85 20204 21271 3 1549.910172 517.6437 ADP-dependent glucokinase OS=Homo sapiens OX=9606 GN=ADPGK PE=1 SV=1 9.6 3600.3 - 2.35E+06 - - - 0.5742 - 2.887 0.473 - 528.1 1 2 0 0.0009 14 0 0 0 1.43E+07 1.69E+07 - - - 6.6308 0.937 221125_WJC_METTL3_EV_vs_WT_F02.21274.21274.2 0.00454 26-Dec R.YILPDEPAIIVHPN.W "sp|Q8IX12|CCAR1_HUMAN,tr|H0YFJ7|H0YFJ7_HUMAN,tr|F5H2E6|F5H2E6_HUMAN,tr|F5H1H2|F5H1H2_HUMAN,tr|A0A0C4DGG8|A0A0C4DGG8_HUMAN" 5 1589.8453 - 20207 21274 2 1589.849229 795.9299 Cell division cycle and apoptosis regulator protein 1 OS=Homo sapiens OX=9606 GN=CCAR1 PE=1 SV=2 4.35 3600.6 - 1.87E+06 - - - 2.4436 - 1.885 0.371 - 317.8 1 1 0 0.0039 14 0 0 0 - - - - - 3.3708 0.9998 221125_WJC_METTL3_EV_vs_WT_F02.21275.21275.3 0.00229 14/44 K.TIEDLATQLNLK.T "sp|P39880|CUX1_HUMAN,tr|A0A2R8Y852|A0A2R8Y852_HUMAN,tr|A0A2R8YDI1|A0A2R8YDI1_HUMAN" 3 1357.7453 1.47 20208 21275 3 1357.744582 453.589 Homeobox protein cut-like 1 OS=Homo sapiens OX=9606 GN=CUX1 PE=1 SV=3 4.37 3600.7 - 1.48E+06 - - - -0.5259 - 2.234 0.348 - 247.9 1 2 0 -0.0007 12 0 0 0 9.11E+06 6.18E+06 - - - 4.6477 0.9999 221125_WJC_METTL3_EV_vs_WT_F02.21277.21277.2 5.37E-05 13/18 K.ENGELLPILR[166.11].G sp|O76003|GLRX3_HUMAN 1 1162.6585 1.28 20210 21277 2 1162.6582 582.3365 Glutaredoxin-3 OS=Homo sapiens OX=9606 GN=GLRX3 PE=1 SV=2 4.53 3600.9 - 1.39E+06 - - - -0.295 - 2.209 0.454 - 651.7 1 2 0 -0.0003 10 0 0 0 1.10E+07 8.60E+06 - - - 4.6064 1 221125_WJC_METTL3_EV_vs_WT_F02.21280.21280.2 1.39E-08 14/28 K.IGNTGGMLDNILASK[136.11].L sp|P53396|ACLY_HUMAN 1 1510.7905 0.7 20213 21280 2 1510.793153 756.4025 ATP-citrate synthase OS=Homo sapiens OX=9606 GN=ACLY PE=1 SV=3 5.84 3601.3 - 911623 - - - 1.7706 - 3.017 0.559 - 717.3 1 2 0 0.0027 15 0 0 0 1.70E+07 2.44E+07 - - - 5.8838 0.9999 221125_WJC_METTL3_EV_vs_WT_F02.21281.21281.3 0.000135 13/44 K.TIEDLATQLNLK[136.11].T "sp|P39880|CUX1_HUMAN,tr|A0A2R8Y852|A0A2R8Y852_HUMAN,tr|A0A2R8YDI1|A0A2R8YDI1_HUMAN" 3 1365.7595 1.4 20214 21281 3 1365.758949 456.2604 Homeobox protein cut-like 1 OS=Homo sapiens OX=9606 GN=CUX1 PE=1 SV=3 4.37 3601.4 - 899474 - - - -0.4005 - 2.105 0.45 - 193.9 1 2 0 -0.0005 12 0 0 0 9.11E+06 6.49E+06 - - - 5.62 0.9958 221125_WJC_METTL3_EV_vs_WT_F02.21282.21282.2 3.88E-05 14/30 R.GIAPIWISGENIPQEK[136.11].D "sp|Q16342|PDCD2_HUMAN,tr|F5H4V9|F5H4V9_HUMAN" 2 1758.9396 0.36 20215 21282 2 1758.947866 880.4771 Programmed cell death protein 2 OS=Homo sapiens OX=9606 GN=PDCD2 PE=1 SV=2 4.53 3601.5 - 525920 - - - 4.7074 - 1.968 0.412 - 397.4 1 2 0 0.0083 16 0 0 0 1.62E+06 4.46E+06 - - - 3.7459 1 221125_WJC_METTL3_EV_vs_WT_F02.21286.21286.2 3.48E-07 18/32 R.AAVEEGIVLGGGC[160.03]ALLR[166.11].C "sp|P10809|CH60_HUMAN,tr|A0A7I2V2X6|A0A7I2V2X6_HUMAN,tr|A0A7I2YQK6|A0A7I2YQK6_HUMAN,tr|A0A7I2V599|A0A7I2V599_HUMAN" 4 1693.9061 1.27 20218 21286 2 1693.905436 847.9603 "60 kDa heat shock protein, mitochondrial OS=Homo sapiens OX=9606 GN=HSPD1 PE=1 SV=2" 4.53 3602 - 1.97E+07 - - - -0.369 - 3.915 0.544 - 872.5 1 2 0 -0.0006 17 0 0 0 5.68E+09 4.47E+09 - - - 6.4142 1 221125_WJC_METTL3_EV_vs_WT_F02.21287.21287.3 2.87E-08 15/64 R.AAVEEGIVLGGGC[160.03]ALLR[166.11].C "sp|P10809|CH60_HUMAN,tr|A0A7I2V2X6|A0A7I2V2X6_HUMAN,tr|A0A7I2YQK6|A0A7I2YQK6_HUMAN,tr|A0A7I2V599|A0A7I2V599_HUMAN" 4 1693.9061 1.27 20219 21287 3 1693.905984 565.6426 "60 kDa heat shock protein, mitochondrial OS=Homo sapiens OX=9606 GN=HSPD1 PE=1 SV=2" 4.53 3602 - 1.06E+07 - - - -0.0455 - 3.357 0.462 - 233.5 1 2 0 -0.0001 17 0 0 0 2.19E+09 1.72E+09 - - - 6.7503 1 221125_WJC_METTL3_EV_vs_WT_F02.21288.21288.3 5.54E-09 18/64 R.AAVEEGIVLGGGC[160.03]ALLR.C "sp|P10809|CH60_HUMAN,tr|A0A7I2V2X6|A0A7I2V2X6_HUMAN,tr|A0A7I2YQK6|A0A7I2YQK6_HUMAN,tr|A0A7I2V599|A0A7I2V599_HUMAN" 4 1683.8978 1.27 20220 21288 3 1683.899309 562.3065 "60 kDa heat shock protein, mitochondrial OS=Homo sapiens OX=9606 GN=HSPD1 PE=1 SV=2" 4.53 3602.1 - 9.20E+06 - - - 0.9015 - 3.617 0.604 - 324.7 1 2 0 0.0015 17 0 0 0 2.20E+09 1.73E+09 - - - 8.5215 0.9999 221125_WJC_METTL3_EV_vs_WT_F02.21289.21289.2 0.000466 14/26 K.LNLVDLAGSENIGR[166.11].S "sp|P52732|KIF11_HUMAN,tr|A0A7I2YQY4|A0A7I2YQY4_HUMAN,tr|A0A7I2V3A9|A0A7I2V3A9_HUMAN,tr|A0A7I2V3V3|A0A7I2V3V3_HUMAN" 4 1479.7921 4.46 20221 21289 2 1479.792295 740.9033 Kinesin-like protein KIF11 OS=Homo sapiens OX=9606 GN=KIF11 PE=1 SV=2 4.37 3602.1 - 7.40E+06 - - - 0.1473 - 2.723 0.445 - 612.9 1 2 0 0.0002 14 0 0 0 1.33E+09 2.98E+08 - - - 4.8415 0.9998 221125_WJC_METTL3_EV_vs_WT_F02.21290.21290.2 6.30E-08 13/24 R.ASPLVAIGQTLAR.Q sp|Q9NSI2|SLX9_HUMAN 1 1295.7561 1.54 20222 21290 2 1295.756221 648.8853 Ribosome biogenesis protein SLX9 homolog OS=Homo sapiens OX=9606 GN=SLX9 PE=1 SV=2 9.79 3602.1 - 3.18E+06 - - - 0.0664 - 2.665 0.379 - 582 1 2 0 0.0001 13 0 0 0 3.94E+08 2.56E+08 - - - 4.356 1 221125_WJC_METTL3_EV_vs_WT_F02.21291.21291.3 1.47E-05 14/56 K.LLQVASPFLEPHLVR.M "sp|O75694|NU155_HUMAN,tr|E9PF10|E9PF10_HUMAN" 2 1717.9879 1.38 20223 21291 3 1717.988566 573.6699 Nuclear pore complex protein Nup155 OS=Homo sapiens OX=9606 GN=NUP155 PE=1 SV=1 6.75 3602.2 - 2.81E+06 - - - 0.3725 - 2.664 0.443 - 230.5 1 2 0 0.0006 15 0 0 0 1.97E+07 1.42E+07 - - - 6.0356 1 221125_WJC_METTL3_EV_vs_WT_F02.21292.21292.2 2.78E-08 16/30 K.LYIGNLSPAVTADDLR[166.11].Q "sp|Q9Y6M1|IF2B2_HUMAN,tr|F8W930|F8W930_HUMAN" 2 1726.9129 2.16 20224 21292 2 1726.912736 864.4637 Insulin-like growth factor 2 mRNA-binding protein 2 OS=Homo sapiens OX=9606 GN=IGF2BP2 PE=1 SV=2 4.21 3602.3 - 2.50E+06 - - - -0.1065 - 3.19 0.605 - 680.1 1 2 0 -0.0002 16 0 0 0 4.85E+07 2.24E+07 - - - 6.3614 0.9999 221125_WJC_METTL3_EV_vs_WT_F02.21293.21293.2 3.85E-10 15/28 K.IGNTGGMLDNILASK.L sp|P53396|ACLY_HUMAN 1 1502.7763 0.7 20225 21293 2 1502.778203 752.3954 ATP-citrate synthase OS=Homo sapiens OX=9606 GN=ACLY PE=1 SV=3 5.84 3602.5 - 2.24E+06 - - - 1.281 - 3.108 0.512 - 884.8 1 2 0 0.0019 15 0 0 0 1.70E+07 2.44E+07 - - - 5.61 0.9997 221125_WJC_METTL3_EV_vs_WT_F02.21295.21295.2 0.676 22-Nov K.GSLGILLGGDYR.A "sp|Q4VCS5|AMOT_HUMAN,tr|E7ERM3|E7ERM3_HUMAN" 2 1219.6561 1 20227 21295 2 1219.656871 610.8353 Angiomotin OS=Homo sapiens OX=9606 GN=AMOT PE=1 SV=1 5.84 3602.6 - 1.48E+06 - - - 0.6428 - 2.343 0.319 - 311.3 1 2 0 0.0008 12 0 0 0 1.65E+07 1.65E+07 - - - 3.6372 0.9861 221125_WJC_METTL3_EV_vs_WT_F02.21296.21296.2 0.116 13/16 V.PSASALIIK.A sp|P30050|RL12_HUMAN 1 898.5488 1.6 20228 21296 2 898.549008 450.2817 60S ribosomal protein L12 OS=Homo sapiens OX=9606 GN=RPL12 PE=1 SV=1 9.18 3602.8 - 1.12E+06 - - - 0.2671 - 2.575 0.289 - 363.5 1 1 0 0.0002 9 0 0 0 7.93E+06 4.95E+06 - - - 3.9119 1 221125_WJC_METTL3_EV_vs_WT_F02.21297.21297.3 1.77E-09 23/84 R.LPPEPGLSDSYSFDYPSDMGPR[166.11].R "tr|E9PAU2|E9PAU2_HUMAN,tr|A0A087WZ13|A0A087WZ13_HUMAN" 2 2436.0819 1.11 20229 21297 3 2436.081758 813.0346 Ribonucleoprotein PTB-binding 1 OS=Homo sapiens OX=9606 GN=RAVER1 PE=1 SV=1 3.84 3602.9 - 1.10E+06 - - - -0.0632 - 3.545 0.667 - 152.2 1 2 0 -0.0002 22 0 0 0 1.27E+07 1.15E+07 - - - 8.9767 0.9998 221125_WJC_METTL3_EV_vs_WT_F02.21298.21298.2 2.79E-05 22-Dec R.VTSLANLISPVR[166.11].N sp|Q7Z628|ARHG8_HUMAN 1 1278.7535 1.03 20230 21298 2 1278.754846 640.384 Neuroepithelial cell-transforming gene 1 protein OS=Homo sapiens OX=9606 GN=NET1 PE=1 SV=1 9.72 3603 - 840714 - - - 1.0479 - 2.488 0.418 - 743.9 1 2 0 0.0013 12 0 0 0 6.37E+06 6.19E+06 - - - 4.5262 0.9998 221125_WJC_METTL3_EV_vs_WT_F02.21305.21305.2 8.16E-06 26-Oct K.VGYYTIPSMDDLAK[136.11].L "sp|P52948|NUP98_HUMAN,tr|A0A3B3ITD8|A0A3B3ITD8_HUMAN" 2 1579.7683 1.39 20236 21305 2 1579.767922 790.8914 Nuclear pore complex protein Nup98-Nup96 OS=Homo sapiens OX=9606 GN=NUP98 PE=1 SV=4 4.21 3603.9 - 7.28E+06 - - - -0.2684 - 1.746 0.539 - 168.3 1 2 0 -0.0004 14 0 0 0 6.90E+07 4.95E+07 - - - 4.4205 0.9982 221125_WJC_METTL3_EV_vs_WT_F02.21306.21306.3 0.0284 Oct-36 K.KLLELDSFLK.E "sp|P61289|PSME3_HUMAN,tr|K7ENH2|K7ENH2_HUMAN,tr|K9J957|K9J957_HUMAN,tr|B7Z8D3|B7Z8D3_HUMAN,tr|A0A087WTV2|A0A087WTV2_HUMAN" 5 1204.7067 1.05 20237 21306 3 1204.70691 402.5762 Proteasome activator complex subunit 3 OS=Homo sapiens OX=9606 GN=PSME3 PE=1 SV=1 6.07 3604 - 396687 - - - 0.1536 - 1.686 0.255 - 155.4 1 2 0 0.0002 10 0 0 0 1.63E+06 1.55E+06 - - - 2.9085 1 221125_WJC_METTL3_EV_vs_WT_F02.21307.21307.3 1.20E-05 14/60 R.QAQIEVVPSASALIIK.A sp|P30050|RL12_HUMAN 1 1665.9665 1.51 20238 21307 3 1665.967005 556.3295 60S ribosomal protein L12 OS=Homo sapiens OX=9606 GN=RPL12 PE=1 SV=1 6 3604.1 - 8.10E+06 - - - 0.2899 - 2.874 0.478 - 303.1 1 2 0 0.0005 16 0 0 0 2.49E+08 1.65E+08 - - - 6.5779 1 221125_WJC_METTL3_EV_vs_WT_F02.21308.21308.2 1.10E-07 16/30 K.LYIGNLSPAVTADDLR.Q "sp|Q9Y6M1|IF2B2_HUMAN,tr|F8W930|F8W930_HUMAN" 2 1716.9046 2.16 20239 21308 2 1716.90419 859.4596 Insulin-like growth factor 2 mRNA-binding protein 2 OS=Homo sapiens OX=9606 GN=IGF2BP2 PE=1 SV=2 4.21 3604.1 - 5.44E+06 - - - -0.2679 - 3.123 0.618 - 588.4 1 2 0 -0.0005 16 0 0 0 4.85E+07 2.24E+07 - - - 6.4052 0.9913 221125_WJC_METTL3_EV_vs_WT_F02.21310.21310.2 4.88E-05 13/26 L.LTPLNLQIDPAIQR.V "sp|P48668|K2C6C_HUMAN,sp|P04259|K2C6B_HUMAN" 2 1590.9093 999 20241 21310 2 1590.911354 796.4619 "Keratin, type II cytoskeletal 6C OS=Homo sapiens OX=9606 GN=KRT6C PE=1 SV=3" 5.84 3604.2 - 3.66E+06 - - - 1.2653 - 2.369 0.553 - 353.9 1 1 0 0.002 14 0 0 0 1.81E+08 0.00E+00 - - - 5.2891 0.9804 221125_WJC_METTL3_EV_vs_WT_F02.21313.21313.2 3.35E-06 18-Oct M.NSFVNDIFER.L "sp|Q8N257|H2B3B_HUMAN,sp|P33778|H2B1B_HUMAN,sp|Q5QNW6|H2B2F_HUMAN,sp|P58876|H2B1D_HUMAN,sp|Q99880|H2B1L_HUMAN,sp|P62807|H2B1C_HUMAN,sp|Q99877|H2B1N_HUMAN,sp|P57053|H2BFS_HUMAN,sp|P23527|H2B1O_HUMAN,sp|O60814|H2B1K_HUMAN,sp|Q93079|H2B1H_HUMAN,sp|Q99879|H2B1M_HUMAN,sp|Q16778|H2B2E_HUMAN,sp|P06899|H2B1J_HUMAN,tr|U3KQK0|U3KQK0_HUMAN" 15 1239.5884 0.94 20244 21313 2 1239.585579 620.8015 Histone H2B type 3-B OS=Homo sapiens OX=9606 GN=H2BU1 PE=1 SV=3 4.37 3604.4 - 3.07E+06 - - - -2.2766 - 1.995 0.516 - 428.1 1 1 0 -0.0028 10 0 0 0 7.93E+07 8.44E+07 - - - 4.7791 0.9903 221125_WJC_METTL3_EV_vs_WT_F02.21314.21314.2 0.000335 18-Nov M.NSFVNDIFER[166.11].L "sp|Q8N257|H2B3B_HUMAN,sp|P33778|H2B1B_HUMAN,sp|Q5QNW6|H2B2F_HUMAN,sp|P58876|H2B1D_HUMAN,sp|Q99880|H2B1L_HUMAN,sp|P62807|H2B1C_HUMAN,sp|Q99877|H2B1N_HUMAN,sp|P57053|H2BFS_HUMAN,sp|P23527|H2B1O_HUMAN,sp|O60814|H2B1K_HUMAN,sp|Q93079|H2B1H_HUMAN,sp|Q99879|H2B1M_HUMAN,sp|Q16778|H2B2E_HUMAN,sp|P06899|H2B1J_HUMAN,tr|U3KQK0|U3KQK0_HUMAN" 15 1249.5967 0.94 20245 21314 2 1249.595423 625.8056 Histone H2B type 3-B OS=Homo sapiens OX=9606 GN=H2BU1 PE=1 SV=3 4.37 3604.4 - 2.94E+06 - - - -0.9987 - 2.032 0.491 - 480 1 1 0 -0.0012 10 0 0 0 7.97E+07 8.47E+07 - - - 4.6462 0.9995 221125_WJC_METTL3_EV_vs_WT_F02.21317.21317.2 1.01E-10 17/30 R.VGWSTMQASLDLGTDK.F "sp|Q92499|DDX1_HUMAN,tr|A0A7I2V2M5|A0A7I2V2M5_HUMAN,tr|A0A7I2V430|A0A7I2V430_HUMAN,tr|A0A7I2V421|A0A7I2V421_HUMAN,tr|A0A7I2V4F0|A0A7I2V4F0_HUMAN,tr|A0A7I2V5X8|A0A7I2V5X8_HUMAN,tr|A0A7I2V4J3|A0A7I2V4J3_HUMAN,tr|A0A087WZ71|A0A087WZ71_HUMAN,tr|A0A7I2YQ77|A0A7I2YQ77_HUMAN" 9 1707.8138 -1 20248 21317 2 1707.808428 854.9142 ATP-dependent RNA helicase DDX1 OS=Homo sapiens OX=9606 GN=DDX1 PE=1 SV=2 4.21 3604.7 - 2.04E+06 - - - -3.1373 - 2.685 0.522 - 400.4 1 2 0 -0.0054 16 0 0 0 0.00E+00 0.00E+00 - - - 5.3231 0.9999 221125_WJC_METTL3_EV_vs_WT_F02.21318.21318.2 0.000281 24-Nov K.SFLTAEDC[160.03]FELGK.V sp|P13674|P4HA1_HUMAN 1 1515.6915 3.01 20249 21318 2 1515.689334 758.853 Prolyl 4-hydroxylase subunit alpha-1 OS=Homo sapiens OX=9606 GN=P4HA1 PE=1 SV=2 4.14 3604.9 - 1.73E+06 - - - -1.4594 - 2.471 0.559 - 291 1 2 0 -0.0022 13 0 0 0 3.34E+07 1.11E+07 - - - 5.4908 1 221125_WJC_METTL3_EV_vs_WT_F02.21319.21319.3 6.43E-07 15/48 R.ASPLVAIGQTLAR.Q sp|Q9NSI2|SLX9_HUMAN 1 1295.7561 1.74 20250 21319 3 1295.755795 432.926 Ribosome biogenesis protein SLX9 homolog OS=Homo sapiens OX=9606 GN=SLX9 PE=1 SV=2 9.79 3605 - 1.20E+06 - - - -0.2624 - 2.741 0.496 - 389.1 1 2 0 -0.0003 13 0 0 0 7.44E+07 4.28E+07 - - - 6.8037 0.9987 221125_WJC_METTL3_EV_vs_WT_F02.21323.21323.2 0.013 16-Sep K.EGSVLDILK[136.11].S sp|P49790|NU153_HUMAN 1 980.5634 1.52 20252 21323 2 980.561735 491.289 Nuclear pore complex protein Nup153 OS=Homo sapiens OX=9606 GN=NUP153 PE=1 SV=2 4.37 3605.5 - 9.05E+06 - - - -1.6593 - 1.812 0.248 - 391.9 1 2 0 -0.0016 9 0 0 0 1.17E+08 7.72E+07 - - - 2.5919 1 221125_WJC_METTL3_EV_vs_WT_F02.21324.21324.3 7.32E-07 27/72 K.IIAATIENAQPILQIDNAR.L sp|P08779|K1C16_HUMAN 1 2063.1375 999 20253 21324 3 2063.13634 688.7198 "Keratin, type I cytoskeletal 16 OS=Homo sapiens OX=9606 GN=KRT16 PE=1 SV=4" 4.37 3605.5 - 1.06E+07 - - - -0.5642 - 4.041 0.614 - 869.6 1 2 0 -0.0012 19 0 0 0 4.39E+09 0.00E+00 - - - 8.8161 0.9895 221125_WJC_METTL3_EV_vs_WT_F02.21327.21327.2 8.57E-08 22-Oct L.YEGIDFYTSITR[166.11].A "sp|P34931|HS71L_HUMAN,sp|P11142|HSP7C_HUMAN,tr|E9PNE6|E9PNE6_HUMAN,tr|A8K7Q2|A8K7Q2_HUMAN,tr|E9PKE3|E9PKE3_HUMAN,tr|E9PN89|E9PN89_HUMAN,tr|Q53FA3|Q53FA3_HUMAN" 7 1473.7015 0.13 20256 21327 2 1473.698658 737.858 Heat shock 70 kDa protein 1-like OS=Homo sapiens OX=9606 GN=HSPA1L PE=1 SV=2 4.37 3605.7 - 8.83E+06 - - - -1.9488 - 2.097 0.628 - 346.6 1 1 0 -0.0029 12 0 0 0 9.17E+06 6.93E+07 - - - 5.6269 1 221125_WJC_METTL3_EV_vs_WT_F02.21330.21330.3 1.33E-05 17/64 K.TVNELQNLTAAEVVVPR[166.11].D sp|Q9NZI8|IF2B1_HUMAN 1 1862.0137 1.73 20259 21330 3 1862.010868 621.6785 Insulin-like growth factor 2 mRNA-binding protein 1 OS=Homo sapiens OX=9606 GN=IGF2BP1 PE=1 SV=2 4.53 3606 - 4.74E+06 - - - -1.5193 - 2.352 0.509 - 402.6 1 2 0 -0.0028 17 0 0 0 3.88E+08 2.25E+08 - - - 6.3747 0.9993 221125_WJC_METTL3_EV_vs_WT_F02.21333.21333.2 0.0698 15/28 R.QLAPLLPSLAPSSAR.Q "sp|O14979|HNRDL_HUMAN,tr|A0A087WUK2|A0A087WUK2_HUMAN" 2 1519.8722 1.69 20262 21333 2 1519.867968 760.9434 Heterogeneous nuclear ribonucleoprotein D-like OS=Homo sapiens OX=9606 GN=HNRNPDL PE=1 SV=3 9.75 3606.4 - 1.56E+06 - - - -2.8029 - 2.646 0.371 - 519.4 1 2 0 -0.0043 15 0 0 0 2.10E+07 1.25E+07 - - - 4.1722 1 221125_WJC_METTL3_EV_vs_WT_F02.21334.21334.2 1.33E-09 17/34 R.LLAVAIGADC[160.03]TYPELTDK.H "sp|Q9Y2L1|RRP44_HUMAN,tr|G3V1J5|G3V1J5_HUMAN" 2 1948.9816 1.58 20263 21334 2 1948.989819 975.4981 Exosome complex exonuclease RRP44 OS=Homo sapiens OX=9606 GN=DIS3 PE=1 SV=2 4.03 3606.5 - 1.25E+06 - - - 4.2273 - 3.378 0.617 - 832.6 1 2 0 0.0082 18 0 0 0 1.69E+07 1.07E+07 - - - 6.5883 0.9881 221125_WJC_METTL3_EV_vs_WT_F02.21335.21335.2 0.187 13/16 V.LGGGC[160.03]ALLR[166.11].C "sp|P10809|CH60_HUMAN,tr|A0A7I2V2X6|A0A7I2V2X6_HUMAN,tr|A0A7I2YQK6|A0A7I2YQK6_HUMAN,tr|A0A7I2V599|A0A7I2V599_HUMAN" 4 925.5043 1.17 20264 21335 2 925.503163 463.7594 "60 kDa heat shock protein, mitochondrial OS=Homo sapiens OX=9606 GN=HSPD1 PE=1 SV=2" 8.25 3606.6 - 1.19E+06 - - - -1.2188 - 2.579 0.366 - 415.3 1 1 0 -0.0011 9 0 0 0 1.40E+07 1.20E+07 - - - 4.4848 0.9749 221125_WJC_METTL3_EV_vs_WT_F02.21336.21336.3 3.53E-05 15/48 R.LGFHLPLEVAYQR[166.11].G "sp|Q15149|PLEC_HUMAN,tr|H0YDN1|H0YDN1_HUMAN" 2 1551.8437 1.75 20265 21336 3 1551.84026 518.2885 Plectin OS=Homo sapiens OX=9606 GN=PLEC PE=1 SV=3 6.75 3606.7 - 906900 - - - -2.2283 - 2.681 0.056 - 357 2 2 0 -0.0035 13 0 0 0 3.16E+07 1.80E+07 - - - 1.6979 1 221125_WJC_METTL3_EV_vs_WT_F02.21338.21338.2 6.34E-09 19/32 K.TVNELQNLTAAEVVVPR[166.11].D sp|Q9NZI8|IF2B1_HUMAN 1 1862.0137 1.74 20267 21338 2 1862.009067 932.0141 Insulin-like growth factor 2 mRNA-binding protein 1 OS=Homo sapiens OX=9606 GN=IGF2BP1 PE=1 SV=2 4.53 3607 - 843877 - - - -2.4866 - 3.662 0.618 - 1468.2 1 2 0 -0.0046 17 0 0 0 2.39E+08 1.37E+08 - - - 6.7953 1 221125_WJC_METTL3_EV_vs_WT_F02.21344.21344.2 0.000199 23/36 K.IIAATIENAQPILQIDNAR.L sp|P08779|K1C16_HUMAN 1 2063.1375 999 20271 21344 2 2063.135661 1032.576 "Keratin, type I cytoskeletal 16 OS=Homo sapiens OX=9606 GN=KRT16 PE=1 SV=4" 4.37 3607.6 - 1.09E+07 - - - -0.8933 - 4.407 0.632 - 1336.9 1 2 0 -0.0018 19 0 0 0 7.54E+08 0.00E+00 - - - 7.3549 0.9922 221125_WJC_METTL3_EV_vs_WT_F02.21345.21345.3 0.00574 13/52 L.LTPLNLQIDPAIQR.V "sp|P48668|K2C6C_HUMAN,sp|P04259|K2C6B_HUMAN" 2 1590.9093 999 20272 21345 3 1590.909408 531.3104 "Keratin, type II cytoskeletal 6C OS=Homo sapiens OX=9606 GN=KRT6C PE=1 SV=3" 5.84 3607.6 - 9.85E+06 - - - 0.0421 - 2.474 0.407 - 179.2 1 1 0 0.0001 14 0 0 0 8.01E+07 0.00E+00 - - - 5.4849 1 221125_WJC_METTL3_EV_vs_WT_F02.21346.21346.3 9.32E-09 17/64 K.TVNELQNLTAAEVVVPR.D sp|Q9NZI8|IF2B1_HUMAN 1 1852.0054 1.73 20273 21346 3 1852.001809 618.3424 Insulin-like growth factor 2 mRNA-binding protein 1 OS=Homo sapiens OX=9606 GN=IGF2BP1 PE=1 SV=2 4.53 3607.7 - 7.73E+06 - - - -1.9536 - 2.986 0.577 - 361.1 1 2 0 -0.0036 17 0 0 0 3.88E+08 2.25E+08 - - - 7.7356 1 221125_WJC_METTL3_EV_vs_WT_F02.21349.21349.2 5.53E-09 18/32 K.TVNELQNLTAAEVVVPR.D sp|Q9NZI8|IF2B1_HUMAN 1 1852.0054 1.75 20276 21349 2 1852.009947 927.01 Insulin-like growth factor 2 mRNA-binding protein 1 OS=Homo sapiens OX=9606 GN=IGF2BP1 PE=1 SV=2 4.53 3607.9 - 5.75E+06 - - - 2.4406 - 3.211 0.577 - 239 1 2 0 0.0045 17 0 0 0 2.39E+08 1.37E+08 - - - 6.1694 0.9995 221125_WJC_METTL3_EV_vs_WT_F02.21350.21350.2 0.0423 16-Sep K.DIVENYFMR[166.11].D "sp|Q13263|TIF1B_HUMAN,tr|M0R2I3|M0R2I3_HUMAN" 2 1195.5571 0.63 20277 21350 2 1195.555674 598.7858 Transcription intermediary factor 1-beta OS=Homo sapiens OX=9606 GN=TRIM28 PE=1 SV=5 4.37 3608 - 3.71E+06 - - - -1.2053 - 1.904 0.341 - 284.1 1 2 0 -0.0014 9 0 0 0 1.89E+07 3.00E+07 - - - 3.4222 0.9992 221125_WJC_METTL3_EV_vs_WT_F02.21353.21353.2 0.0798 14/20 R.TSLALDESLFR[166.11].G "sp|Q86U42|PABP2_HUMAN,tr|B4DEH8|B4DEH8_HUMAN,tr|G3V4T2|G3V4T2_HUMAN,tr|H0YJH9|H0YJH9_HUMAN,tr|A0A7I2V383|A0A7I2V383_HUMAN" 5 1260.6589 1.26 20280 21353 2 1260.654982 631.3367 Polyadenylate-binding protein 2 OS=Homo sapiens OX=9606 GN=PABPN1 PE=1 SV=3 4.37 3608.3 - 3.16E+06 - - - -3.1372 - 2.75 0.344 - 695.4 1 2 0 -0.004 11 0 0 0 1.40E+08 1.12E+08 - - - 4.3172 1 221125_WJC_METTL3_EV_vs_WT_F02.21357.21357.2 1.38E-07 16/26 R.ESAAADAGFALFEK.K sp|P52756|RBM5_HUMAN 1 1425.6776 2.2 20284 21357 2 1425.676703 713.8461 RNA-binding protein 5 OS=Homo sapiens OX=9606 GN=RBM5 PE=1 SV=2 4.14 3608.7 - 1.62E+06 - - - -0.6362 - 2.723 0.602 - 1121.1 1 2 0 -0.0009 14 0 0 0 1.44E+07 6.56E+06 - - - 6.0009 0.9809 221125_WJC_METTL3_EV_vs_WT_F02.21358.21358.2 0.0687 14/16 V.LGGGC[160.03]ALLR.C "sp|P10809|CH60_HUMAN,tr|A0A7I2V2X6|A0A7I2V2X6_HUMAN,tr|A0A7I2YQK6|A0A7I2YQK6_HUMAN,tr|A0A7I2V599|A0A7I2V599_HUMAN" 4 915.496 1.17 20285 21358 2 915.494122 458.7553 "60 kDa heat shock protein, mitochondrial OS=Homo sapiens OX=9606 GN=HSPD1 PE=1 SV=2" 8.25 3608.8 - 1.34E+06 - - - -2.0743 - 2.702 0.36 - 497.8 1 1 0 -0.0019 9 0 0 0 1.40E+07 1.20E+07 - - - 4.575 0.9985 221125_WJC_METTL3_EV_vs_WT_F02.21361.21361.2 0.0976 16-Aug K.EGSVLDILK.S sp|P49790|NU153_HUMAN 1 972.5492 1.52 20287 21361 2 972.548162 487.2819 Nuclear pore complex protein Nup153 OS=Homo sapiens OX=9606 GN=NUP153 PE=1 SV=2 4.37 3609.1 - 1.21E+07 - - - -1.0282 - 1.661 0.229 - 320.4 1 2 0 -0.001 9 0 0 0 1.17E+08 7.72E+07 - - - 2.2001 0.9996 221125_WJC_METTL3_EV_vs_WT_F02.21364.21364.2 1.59E-05 24-Dec R.ASPLVAIGQTLAR[166.11].Q sp|Q9NSI2|SLX9_HUMAN 1 1305.7644 1.53 20290 21364 2 1305.762008 653.8895 Ribosome biogenesis protein SLX9 homolog OS=Homo sapiens OX=9606 GN=SLX9 PE=1 SV=2 9.79 3609.2 - 5.31E+06 - - - -1.8357 - 2.478 0.367 - 447 1 2 0 -0.0024 13 0 0 0 3.78E+08 2.47E+08 - - - 4.0799 0.9999 221125_WJC_METTL3_EV_vs_WT_F02.21365.21365.2 0.00279 20-Dec R.AGLEDLQVAFR.A sp|Q9NZT1|CALL5_HUMAN 1 1217.6404 9.52 20291 21365 2 1217.640295 609.8275 Calmodulin-like protein 5 OS=Homo sapiens OX=9606 GN=CALML5 PE=1 SV=2 4.37 3609.3 - 4.24E+06 - - - -0.1166 - 2.741 0.372 - 465.4 1 2 0 -0.0001 11 0 0 0 1.09E+08 1.14E+07 - - - 4.5163 0.9998 221125_WJC_METTL3_EV_vs_WT_F02.21368.21368.2 2.25E-06 13/20 K.YATLSLFNTYK[136.11].G "sp|Q9Y520|PRC2C_HUMAN,tr|E7EPN9|E7EPN9_HUMAN" 2 1327.6904 0.82 20294 21368 2 1327.691573 664.8525 Protein PRRC2C OS=Homo sapiens OX=9606 GN=PRRC2C PE=1 SV=4 8.5 3609.6 - 2.90E+06 - - - 0.9181 - 2.376 0.42 - 498 1 2 0 0.0012 11 0 0 0 6.19E+07 7.56E+07 - - - 4.4839 0.9323 221125_WJC_METTL3_EV_vs_WT_F02.21369.21369.2 9.59 14-Jul K.EVAELVGR[166.11].V sp|Q86UT6|NLRX1_HUMAN 1 881.4846 0.001 20295 21369 2 881.483588 441.7496 NLR family member X1 OS=Homo sapiens OX=9606 GN=NLRX1 PE=1 SV=1 4.53 3609.7 - 2.22E+06 - - - -1.1492 - 1.274 0.002 - 67.7 4 2 0 -0.001 8 0 0 0 0.00E+00 2.13E+07 - - - -0.4831 1 221125_WJC_METTL3_EV_vs_WT_F02.21371.21371.2 4.61E-13 17/34 R.TIGTGLVTNTLAMTEEEK[136.11].N sp|P49411|EFTU_HUMAN 1 1914.97 1.3 20297 21371 2 1914.965121 958.4923 "Elongation factor Tu, mitochondrial OS=Homo sapiens OX=9606 GN=TUFM PE=1 SV=2" 4.25 3609.9 - 1.45E+06 - - - -2.5264 - 3.366 0.652 - 665.5 1 2 0 -0.0048 18 0 0 0 9.42E+07 7.26E+07 - - - 6.8392 1 221125_WJC_METTL3_EV_vs_WT_F02.21374.21374.2 5.20E-07 14/34 R.LLAVAIGADC[160.03]TYPELTDK[136.11].H "sp|Q9Y2L1|RRP44_HUMAN,tr|G3V1J5|G3V1J5_HUMAN" 2 1956.9958 1.58 20300 21374 2 1957.001572 979.5052 Exosome complex exonuclease RRP44 OS=Homo sapiens OX=9606 GN=DIS3 PE=1 SV=2 4.03 3610.3 - 973100 - - - 2.9596 - 2.953 0.566 - 455.4 1 2 0 0.0058 18 0 0 0 1.69E+07 1.07E+07 - - - 5.8818 0.9996 221125_WJC_METTL3_EV_vs_WT_F02.21377.21377.2 4.43E-05 26-Dec K.EAAWAISNLTISGR[166.11].K "sp|O00505|IMA4_HUMAN,sp|O00629|IMA3_HUMAN,tr|A0A7I2YQ95|A0A7I2YQ95_HUMAN,tr|H7C4F6|H7C4F6_HUMAN" 4 1497.7815 0.91 20302 21377 2 1497.778338 749.898 Importin subunit alpha-4 OS=Homo sapiens OX=9606 GN=KPNA3 PE=1 SV=2 6.1 3610.7 - 1.23E+06 - - - -2.1191 - 2.316 0.439 - 471.6 1 2 0 -0.0032 14 0 0 0 2.60E+07 2.84E+07 - - - 4.39 1 221125_WJC_METTL3_EV_vs_WT_F02.21379.21379.4 7.29E-09 23/108 K.IIAATIENAQPILQIDNAR.L sp|P08779|K1C16_HUMAN 1 2063.1375 2.26 20303 21379 4 2063.136281 516.7917 "Keratin, type I cytoskeletal 16 OS=Homo sapiens OX=9606 GN=KRT16 PE=1 SV=4" 4.37 3611 - 3.44E+06 - - - -0.5928 - 3.317 0.563 - 496.8 1 2 0 -0.0012 19 0 0 0 4.76E+07 2.11E+07 - - - 4.5316 1 221125_WJC_METTL3_EV_vs_WT_F02.21381.21381.3 6.34E-06 14/48 K.TFLVWVNEEDHLR.V "sp|P12277|KCRB_HUMAN,tr|H0YJG0|H0YJG0_HUMAN" 2 1656.826 0.77 20305 21381 3 1656.828076 553.2826 Creatine kinase B-type OS=Homo sapiens OX=9606 GN=CKB PE=1 SV=1 4.65 3611.1 - 2.03E+06 - - - 1.2494 - 2.677 0.499 - 238 1 2 0 0.0021 13 0 0 0 1.87E+07 2.41E+07 - - - 6.7726 0.9305 221125_WJC_METTL3_EV_vs_WT_F02.21382.21382.2 2.58E-05 Dec-32 K.GNPQGFNQGLDC[160.03]DVIVA.E sp|Q86U44|MTA70_HUMAN 1 1802.8257 - 20306 21382 2 1802.827729 902.4202 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 3.56 3611.2 - 2.02E+06 - - - 1.0988 - 2.139 0.211 - 287 1 1 0 0.002 17 0 0 0 - - - - - 2.4682 0.9971 221125_WJC_METTL3_EV_vs_WT_F02.21383.21383.3 8.43E-05 17/44 K.LLHHLSDLALTL.P "sp|Q86U44|MTA70_HUMAN,tr|B4E349|B4E349_HUMAN,tr|F5H6D8|F5H6D8_HUMAN,tr|H0YFV6|H0YFV6_HUMAN,tr|B4DTN4|B4DTN4_HUMAN" 5 1344.7765 - 20307 21383 3 1344.774611 449.2661 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 5.97 3611.3 - 1.91E+06 - - - -1.4315 - 3.23 0.461 - 521.6 1 1 0 -0.0019 12 0 0 0 - - - - - 6.9291 0.9999 221125_WJC_METTL3_EV_vs_WT_F02.21384.21384.2 3.93E-06 13/24 R.TVQSLEIDLDSMR[166.11].N "sp|P05783|K1C18_HUMAN,tr|F8VZY9|F8VZY9_HUMAN" 2 1515.7478 2.54 20308 21384 2 1515.749511 758.8812 "Keratin, type I cytoskeletal 18 OS=Homo sapiens OX=9606 GN=KRT18 PE=1 SV=2" 4.03 3611.4 - 1.76E+06 - - - 1.1097 - 2.508 0.543 - 580.5 1 2 0 0.0017 13 0 0 0 5.01E+07 1.97E+07 - - - 5.411 0.9997 221125_WJC_METTL3_EV_vs_WT_F02.21385.21385.3 4.50E-05 Dec-48 R.TVQSLEIDLDSMR.N "sp|P05783|K1C18_HUMAN,tr|F8VZY9|F8VZY9_HUMAN" 2 1505.7396 2.32 20309 21385 3 1505.734694 502.9205 "Keratin, type I cytoskeletal 18 OS=Homo sapiens OX=9606 GN=KRT18 PE=1 SV=2" 4.03 3611.6 - 1.70E+06 - - - -3.231 - 2.587 0.404 - 304.5 1 2 0 -0.0049 13 0 0 0 1.95E+07 8.42E+06 - - - 5.6199 0.9694 221125_WJC_METTL3_EV_vs_WT_F02.21387.21387.2 3.10E-05 16-Nov Q.PILQIDNAR.L sp|P08779|K1C16_HUMAN 1 1038.5822 9.94 20311 21387 2 1038.5831 520.2984 "Keratin, type I cytoskeletal 16 OS=Homo sapiens OX=9606 GN=KRT16 PE=1 SV=4" 6.27 3611.8 - 1.33E+06 - - - 0.8723 - 2.231 0.249 - 454.7 1 1 0 0.0009 9 0 0 0 2.03E+07 2.04E+06 - - - 3.2014 0.9994 221125_WJC_METTL3_EV_vs_WT_F02.21392.21392.2 2.73E-05 15/26 R.AAVQFLNNAWGIQK[136.11].K sp|Q9UMY1|NOL7_HUMAN 1 1566.8398 2.04 20314 21392 2 1566.844841 784.4272 Nucleolar protein 7 OS=Homo sapiens OX=9606 GN=NOL7 PE=1 SV=2 8.8 3612.4 - 1.25E+06 - - - 3.2096 - 2.953 0.437 - 1042.3 1 2 0 0.005 14 0 0 0 3.55E+07 1.74E+07 - - - 4.9844 0.9997 221125_WJC_METTL3_EV_vs_WT_F02.21396.21396.3 0.0033 Nov-48 R.TVQSLEIDLDSMR[166.11].N "sp|P05783|K1C18_HUMAN,tr|F8VZY9|F8VZY9_HUMAN" 2 1515.7478 2.32 20318 21396 3 1515.745968 506.2566 "Keratin, type I cytoskeletal 18 OS=Homo sapiens OX=9606 GN=KRT18 PE=1 SV=2" 4.03 3612.9 - 994544 - - - -1.2278 - 1.987 0.356 - 211.4 1 2 0 -0.0019 13 0 0 0 1.95E+07 8.42E+06 - - - 4.3702 1 221125_WJC_METTL3_EV_vs_WT_F02.21397.21397.2 1.33E-09 13/32 R.K[136.11]PLVIIAEDVDGEALST.L "sp|P10809|CH60_HUMAN,tr|A0A7I2V2X6|A0A7I2V2X6_HUMAN,tr|A0A7I2YQK6|A0A7I2YQK6_HUMAN,tr|A0A7I2V599|A0A7I2V599_HUMAN,tr|A0A7I2YQ71|A0A7I2YQ71_HUMAN,tr|A0A7I2V5M1|A0A7I2V5M1_HUMAN,tr|A0A7I2V5K3|A0A7I2V5K3_HUMAN,tr|A0A7I2V369|A0A7I2V369_HUMAN" 8 1776.96 1.42 20319 21397 2 1776.95732 889.4873 "60 kDa heat shock protein, mitochondrial OS=Homo sapiens OX=9606 GN=HSPD1 PE=1 SV=2" 3.92 3613 - 776732 - - - -1.5341 - 2.888 0.609 - 390.9 1 1 0 -0.0027 17 0 0 0 2.74E+07 1.93E+07 - - - 6.1457 1 221125_WJC_METTL3_EV_vs_WT_F02.21400.21400.2 4.11E-07 21/32 R.AAVEEGIVLGGGC[160.03]ALLR.C "sp|P10809|CH60_HUMAN,tr|A0A7I2V2X6|A0A7I2V2X6_HUMAN,tr|A0A7I2YQK6|A0A7I2YQK6_HUMAN,tr|A0A7I2V599|A0A7I2V599_HUMAN" 4 1683.8978 1.27 20320 21400 2 1683.896666 842.9562 "60 kDa heat shock protein, mitochondrial OS=Homo sapiens OX=9606 GN=HSPD1 PE=1 SV=2" 4.53 3613.4 - 1.04E+08 - - - -0.6681 - 4.009 0.548 - 1306.5 1 2 0 -0.0011 17 0 0 0 5.68E+09 4.47E+09 - - - 6.502 0.9998 221125_WJC_METTL3_EV_vs_WT_F02.21402.21402.2 0.000332 18-Nov K.QVSDLISVLR[166.11].E "sp|P17844|DDX5_HUMAN,tr|J3KTA4|J3KTA4_HUMAN,tr|A0A0G2JLI4|A0A0G2JLI4_HUMAN" 3 1138.6585 1.47 20322 21402 2 1138.657689 570.3365 Probable ATP-dependent RNA helicase DDX5 OS=Homo sapiens OX=9606 GN=DDX5 PE=1 SV=1 5.84 3613.5 - 1.91E+07 - - - -0.75 - 1.977 0.402 - 621.6 1 2 0 -0.0009 10 0 0 0 1.20E+09 8.12E+08 - - - 3.9124 0.9889 221125_WJC_METTL3_EV_vs_WT_F02.21403.21403.2 0.0185 26-Aug K.LFHVSEDPSDLNEK.H sp|P35573|GDE_HUMAN 1 1628.7682 999 20323 21403 2 1628.761651 815.3914 Glycogen debranching enzyme OS=Homo sapiens OX=9606 GN=AGL PE=1 SV=3 4.31 3613.5 - 9.31E+06 - - - -4.0307 - 1.433 0.31 - 100.9 1 2 0 -0.0066 14 0 0 0 1.80E+08 0.00E+00 - - - 2.2314 0.9982 221125_WJC_METTL3_EV_vs_WT_F02.21405.21405.2 0.000213 26-Dec R.AAVQFLNNAWGIQK.K sp|Q9UMY1|NOL7_HUMAN 1 1558.8256 2.1 20325 21405 2 1558.832041 780.4201 Nucleolar protein 7 OS=Homo sapiens OX=9606 GN=NOL7 PE=1 SV=2 8.8 3613.7 - 2.14E+06 - - - 4.1243 - 2.37 0.415 - 508.8 1 2 0 0.0064 14 0 0 0 3.66E+07 1.74E+07 - - - 4.2696 0.9999 221125_WJC_METTL3_EV_vs_WT_F02.21408.21408.2 1.51E-07 22-Dec K.EIEDFDSLEALR.L "sp|P46060|RAGP1_HUMAN,tr|B0QYT4|B0QYT4_HUMAN,tr|B0QYT5|B0QYT5_HUMAN" 3 1435.6831 1.62 20328 21408 2 1435.682756 718.8488 Ran GTPase-activating protein 1 OS=Homo sapiens OX=9606 GN=RANGAP1 PE=1 SV=1 3.83 3614.1 - 1.85E+06 - - - -0.2326 - 2.356 0.491 - 467 1 2 0 -0.0003 12 0 0 0 2.75E+07 1.69E+07 - - - 4.9222 0.9988 221125_WJC_METTL3_EV_vs_WT_F02.21410.21410.3 0.000144 18/64 R.QLALETIDINKDPYFMK.N "sp|Q15428|SF3A2_HUMAN,tr|K7EMT0|K7EMT0_HUMAN" 2 2038.0445 17.9 20330 21410 3 2038.048857 680.3554 Splicing factor 3A subunit 2 OS=Homo sapiens OX=9606 GN=SF3A2 PE=1 SV=2 4.56 3614.3 - 1.40E+06 - - - 2.131 - 2.646 0.356 - 336.7 1 2 1 0.0043 17 0 0 0 1.23E+07 6.84E+05 - - - 4.9661 1 221125_WJC_METTL3_EV_vs_WT_F02.21411.21411.2 4.24E-09 17/36 R.SSPAAFINPPIGTVTPALK.L "sp|Q9BY77|PDIP3_HUMAN,tr|F6VRR5|F6VRR5_HUMAN,tr|F8WCX5|F8WCX5_HUMAN,tr|Q6R954|Q6R954_HUMAN,tr|Q8WUT1|Q8WUT1_HUMAN,tr|F8WEE2|F8WEE2_HUMAN" 6 1880.0407 1.88 20331 21411 2 1880.047222 941.0277 Polymerase delta-interacting protein 3 OS=Homo sapiens OX=9606 GN=POLDIP3 PE=1 SV=2 8.47 3614.4 - 974547 - - - 3.4425 - 2.69 0.646 - 421.1 1 2 0 0.0065 19 0 0 0 2.25E+07 1.20E+07 - - - 6.2432 0.9999 221125_WJC_METTL3_EV_vs_WT_F02.21413.21413.2 0.00337 14/20 R.TSLALDESLFR.G "sp|Q86U42|PABP2_HUMAN,tr|B4DEH8|B4DEH8_HUMAN,tr|G3V4T2|G3V4T2_HUMAN,tr|H0YJH9|H0YJH9_HUMAN,tr|A0A7I2V383|A0A7I2V383_HUMAN" 5 1250.6507 1.26 20332 21413 2 1250.651118 626.3326 Polyadenylate-binding protein 2 OS=Homo sapiens OX=9606 GN=PABPN1 PE=1 SV=3 4.37 3614.6 - 8.12E+06 - - - 0.3606 - 2.673 0.425 - 1044 1 2 0 0.0005 11 0 0 0 1.40E+08 1.12E+08 - - - 4.8397 1 221125_WJC_METTL3_EV_vs_WT_F02.21416.21416.3 0.00016 16/64 R.LFVGNLPADITEDEFKR.L sp|P23246|SFPQ_HUMAN 1 1963.0051 0.65 20334 21416 3 1963.004574 655.3423 "Splicing factor, proline- and glutamine-rich OS=Homo sapiens OX=9606 GN=SFPQ PE=1 SV=2" 4.32 3614.9 - 9.65E+06 - - - -0.2639 - 2.713 0.525 - 278.7 1 2 0 -0.0005 17 0 0 0 9.85E+07 1.50E+08 - - - 6.9145 1 221125_WJC_METTL3_EV_vs_WT_F02.21419.21419.2 7.19E-10 15/32 R.KPLVIIAEDVDGEALST.L "sp|P10809|CH60_HUMAN,tr|A0A7I2V2X6|A0A7I2V2X6_HUMAN,tr|A0A7I2YQK6|A0A7I2YQK6_HUMAN,tr|A0A7I2V599|A0A7I2V599_HUMAN,tr|A0A7I2YQ71|A0A7I2YQ71_HUMAN,tr|A0A7I2V5M1|A0A7I2V5M1_HUMAN,tr|A0A7I2V5K3|A0A7I2V5K3_HUMAN,tr|A0A7I2V369|A0A7I2V369_HUMAN" 8 1768.9458 1.42 20337 21419 2 1768.94689 885.4802 "60 kDa heat shock protein, mitochondrial OS=Homo sapiens OX=9606 GN=HSPD1 PE=1 SV=2" 3.92 3615.1 - 2.24E+06 - - - 0.5902 - 3.323 0.633 - 826.1 1 1 0 0.001 17 0 0 0 2.74E+07 1.93E+07 - - - 6.6684 0.9999 221125_WJC_METTL3_EV_vs_WT_F02.21420.21420.3 0.000237 14/48 R.ASPLVAIGQTLAR[166.11].Q sp|Q9NSI2|SLX9_HUMAN 1 1305.7644 1.75 20338 21420 3 1305.763265 436.2621 Ribosome biogenesis protein SLX9 homolog OS=Homo sapiens OX=9606 GN=SLX9 PE=1 SV=2 9.79 3615.2 - 2.10E+06 - - - -0.8731 - 2.38 0.406 - 418.3 1 2 0 -0.0011 13 0 0 0 7.30E+07 4.17E+07 - - - 5.4171 0.9999 221125_WJC_METTL3_EV_vs_WT_F02.21421.21421.3 2.21E-05 14/40 K.IK[136.11]YPENFFLLR[166.11].G "sp|P62136|PP1A_HUMAN,sp|P62140|PP1B_HUMAN,sp|P36873|PP1G_HUMAN,tr|C9JP48|C9JP48_HUMAN,tr|C9J9S3|C9J9S3_HUMAN,tr|E7ETD8|E7ETD8_HUMAN,tr|A0A087WYY5|A0A087WYY5_HUMAN,tr|A0A7I2V4F7|A0A7I2V4F7_HUMAN,tr|F8W0W8|F8W0W8_HUMAN,tr|F8VYE8|F8VYE8_HUMAN,tr|F8VR82|F8VR82_HUMAN,tr|E9PMD7|E9PMD7_HUMAN" 12 1456.8197 1.08 20339 21421 3 1456.820075 486.6139 Serine\threonine-protein phosphatase PP1-alpha catalytic subunit OS=Homo sapiens OX=9606 GN=PPP1CA PE=1 SV=1 8.59 3615.3 - 1.63E+06 - - - 0.2286 - 2.564 0.467 - 248.4 1 2 1 0.0003 11 0 0 0 2.22E+07 2.05E+07 - - - 6.4213 0.9999 221125_WJC_METTL3_EV_vs_WT_F02.21422.21422.2 6.46E-06 14/24 R.QVEVINFGDC[160.03]LVR.S "sp|P46060|RAGP1_HUMAN,tr|H0Y4Q3|H0Y4Q3_HUMAN" 2 1547.7766 1.28 20340 21422 2 1547.776374 774.8956 Ran GTPase-activating protein 1 OS=Homo sapiens OX=9606 GN=RANGAP1 PE=1 SV=1 4.37 3615.4 - 1.33E+06 - - - -0.1544 - 2.613 0.557 - 745.6 1 2 0 -0.0002 13 0 0 0 4.33E+07 3.38E+07 - - - 5.6201 0.9428 221125_WJC_METTL3_EV_vs_WT_F02.21426.21426.2 9.65E-06 17/34 K.AGGYPLVYPGHPLQPAAL.S sp|Q9H7S9|ZN703_HUMAN 1 1819.9621 - 20344 21426 2 1819.956753 910.9883 Zinc finger protein 703 OS=Homo sapiens OX=9606 GN=ZNF703 PE=1 SV=1 6.78 3615.9 - 674628 - - - -2.9407 - 2.47 0.353 - 552.7 1 1 0 -0.0054 18 0 0 0 - - - - - 3.8696 0.9996 221125_WJC_METTL3_EV_vs_WT_F02.21427.21427.2 0.0171 24-Oct K.TEDSLMPEEEFLR[166.11].R sp|Q15459|SF3A1_HUMAN 1 1604.7268 1.14 20345 21427 2 1604.728914 803.3707 Splicing factor 3A subunit 1 OS=Homo sapiens OX=9606 GN=SF3A1 PE=1 SV=1 3.91 3616 - 621076 - - - 1.3429 - 2.227 0.345 - 112.4 1 2 0 0.0022 13 0 0 0 9.04E+06 7.95E+06 - - - 3.6434 0.9997 221125_WJC_METTL3_EV_vs_WT_F02.21431.21431.2 3.89E-06 18-Dec K.QVSDLISVLR.E "sp|P17844|DDX5_HUMAN,tr|J3KTA4|J3KTA4_HUMAN,tr|A0A0G2JLI4|A0A0G2JLI4_HUMAN" 3 1128.6503 1.47 20347 21431 2 1128.650752 565.3324 Probable ATP-dependent RNA helicase DDX5 OS=Homo sapiens OX=9606 GN=DDX5 PE=1 SV=1 5.84 3616.5 - 1.26E+08 - - - 0.4244 - 2.147 0.363 - 715.1 1 2 0 0.0005 10 0 0 0 1.20E+09 8.12E+08 - - - 3.8547 1 221125_WJC_METTL3_EV_vs_WT_F02.21432.21432.3 1.70E-08 17/64 R.LFVGNLPADITEDEFK[136.11]R[166.11].L sp|P23246|SFPQ_HUMAN 1 1981.0276 1.35 20348 21432 3 1981.026825 661.3498 "Splicing factor, proline- and glutamine-rich OS=Homo sapiens OX=9606 GN=SFPQ PE=1 SV=2" 4.32 3616.6 - 1.56E+07 - - - -0.372 - 2.882 0.573 - 356.7 1 2 0 -0.0007 17 0 0 0 2.11E+08 1.56E+08 - - - 7.6022 1 221125_WJC_METTL3_EV_vs_WT_F02.21434.21434.2 5.85E-09 26-Nov K.FGYVDFESAEDLEK[136.11].A "sp|P19338|NUCL_HUMAN,tr|A0A7I2V506|A0A7I2V506_HUMAN,tr|A0A7I2V699|A0A7I2V699_HUMAN,tr|A0A7I2V2U7|A0A7I2V2U7_HUMAN,tr|A0A7I2V3F3|A0A7I2V3F3_HUMAN,tr|A0A7I2V428|A0A7I2V428_HUMAN,tr|A0A7I2V349|A0A7I2V349_HUMAN,tr|H7BY16|H7BY16_HUMAN,tr|A0A7I2V5M5|A0A7I2V5M5_HUMAN,tr|A0A7I2V2S8|A0A7I2V2S8_HUMAN,tr|C9JLB1|C9JLB1_HUMAN" 11 1655.7446 0.69 20350 21434 2 1655.743091 828.8796 Nucleolin OS=Homo sapiens OX=9606 GN=NCL PE=1 SV=3 3.83 3616.6 - 9.12E+06 - - - -0.9319 - 2.699 0.672 - 170.2 1 2 0 -0.0015 14 0 0 0 1.01E+08 1.46E+08 - - - 6.4955 1 221125_WJC_METTL3_EV_vs_WT_F02.21435.21435.2 3.93E-10 14/26 R.WSSLAC[160.03]NIALDAVK[136.11].M "sp|P49368|TCPG_HUMAN,tr|Q5SZW8|Q5SZW8_HUMAN,tr|E9PRC8|E9PRC8_HUMAN,tr|B4DUR8|B4DUR8_HUMAN,tr|E9PQ35|E9PQ35_HUMAN,tr|Q5SZX6|Q5SZX6_HUMAN" 6 1554.7956 0.23 20351 21435 2 1554.794736 778.4051 T-complex protein 1 subunit gamma OS=Homo sapiens OX=9606 GN=CCT3 PE=1 SV=4 5.83 3616.7 - 6.46E+06 - - - -0.5325 - 2.579 0.629 - 418.9 1 2 0 -0.0008 14 0 0 0 4.56E+07 1.98E+08 - - - 6.064 0.9999 221125_WJC_METTL3_EV_vs_WT_F02.21436.21436.3 6.01E-07 Nov-40 K.IKYPENFFLLR.G "sp|P62136|PP1A_HUMAN,sp|P62140|PP1B_HUMAN,sp|P36873|PP1G_HUMAN,tr|C9JP48|C9JP48_HUMAN,tr|C9J9S3|C9J9S3_HUMAN,tr|E7ETD8|E7ETD8_HUMAN,tr|A0A087WYY5|A0A087WYY5_HUMAN,tr|A0A7I2V4F7|A0A7I2V4F7_HUMAN,tr|F8W0W8|F8W0W8_HUMAN,tr|F8VYE8|F8VYE8_HUMAN,tr|F8VR82|F8VR82_HUMAN,tr|E9PMD7|E9PMD7_HUMAN" 12 1438.7973 1.08 20352 21436 3 1438.797474 480.6064 Serine\threonine-protein phosphatase PP1-alpha catalytic subunit OS=Homo sapiens OX=9606 GN=PPP1CA PE=1 SV=1 8.59 3616.8 - 2.14E+06 - - - 0.1404 - 2.404 0.482 - 155.9 1 2 1 0.0002 11 0 0 0 2.22E+07 2.05E+07 - - - 6.4056 0.9999 221125_WJC_METTL3_EV_vs_WT_F02.21437.21437.2 3.30E-08 15/26 K.VVNEINIEDLC[160.03]LTK[136.11].A "sp|Q8N5K1|CISD2_HUMAN,tr|D6RCF4|D6RCF4_HUMAN" 2 1666.8691 1.22 20353 21437 2 1666.866776 834.4418 CDGSH iron-sulfur domain-containing protein 2 OS=Homo sapiens OX=9606 GN=CISD2 PE=1 SV=1 4.14 3616.9 - 2.03E+06 - - - -1.408 - 3.075 0.467 - 892.8 1 2 0 -0.0023 14 0 0 0 2.33E+07 1.90E+07 - - - 5.3084 0.9999 221125_WJC_METTL3_EV_vs_WT_F02.21438.21438.2 1.83E-10 15/26 M.PLFATNPFDQDVEK.A "sp|Q92783|STAM1_HUMAN,tr|C9J1E5|C9J1E5_HUMAN" 2 1619.7831 25.92 20354 21438 2 1619.784814 810.8988 Signal transducing adapter molecule 1 OS=Homo sapiens OX=9606 GN=STAM PE=1 SV=3 4.03 3617 - 1.41E+06 - - - 1.0347 - 3.102 0.437 - 575.7 1 2 0 0.0017 14 0 0 0 1.93E+07 7.43E+05 - - - 5.109 1 221125_WJC_METTL3_EV_vs_WT_F02.21440.21440.2 4.84E-12 15/36 R.SSPAAFINPPIGTVTPALK[136.11].L "sp|Q9BY77|PDIP3_HUMAN,tr|F6VRR5|F6VRR5_HUMAN,tr|F8WCX5|F8WCX5_HUMAN,tr|Q6R954|Q6R954_HUMAN,tr|Q8WUT1|Q8WUT1_HUMAN,tr|F8WEE2|F8WEE2_HUMAN" 6 1888.0549 1.82 20356 21440 2 1888.055362 945.0348 Polymerase delta-interacting protein 3 OS=Homo sapiens OX=9606 GN=POLDIP3 PE=1 SV=2 8.47 3617.3 - 954781 - - - 0.2182 - 2.833 0.683 - 358.7 1 2 0 0.0004 19 0 0 0 2.75E+07 1.51E+07 - - - 6.6457 1 221125_WJC_METTL3_EV_vs_WT_F02.21442.21442.2 3.34E-06 15/28 K.FIIENTDLAVANSIR.R "sp|P19387|RPB3_HUMAN,tr|H3BRR2|H3BRR2_HUMAN" 2 1674.8941 0.02 20358 21442 2 1674.890552 838.4543 DNA-directed RNA polymerase II subunit RPB3 OS=Homo sapiens OX=9606 GN=POLR2C PE=1 SV=2 4.37 3617.5 - 737725 - - - -2.1094 - 3.046 0.559 - 666.9 1 2 0 -0.0035 15 0 0 0 1.59E+07 8.96E+08 - - - 5.9071 0.9993 221125_WJC_METTL3_EV_vs_WT_F02.21443.21443.3 0.00768 Oct-52 K.LVLIGSNHSLPFLK.F "sp|O15027|SC16A_HUMAN,tr|A0A3F2YNX0|A0A3F2YNX0_HUMAN,tr|A0A3F2YNZ0|A0A3F2YNZ0_HUMAN,tr|X6RGP5|X6RGP5_HUMAN,tr|F1T0I1|F1T0I1_HUMAN,tr|A0A0C4DH09|A0A0C4DH09_HUMAN" 6 1536.9028 1.31 20359 21443 3 1536.899774 513.3082 Protein transport protein Sec16A OS=Homo sapiens OX=9606 GN=SEC16A PE=1 SV=4 8.76 3617.7 - 700473 - - - -1.9689 - 1.805 0.35 - 65.2 1 2 0 -0.003 14 0 0 0 5.30E+06 4.04E+06 - - - 4.0107 0.9968 221125_WJC_METTL3_EV_vs_WT_F02.21444.21444.3 0.000254 Nov-52 K.FGYVDFESAEDLEK[136.11].A "sp|P19338|NUCL_HUMAN,tr|A0A7I2V506|A0A7I2V506_HUMAN,tr|A0A7I2V699|A0A7I2V699_HUMAN,tr|A0A7I2V2U7|A0A7I2V2U7_HUMAN,tr|A0A7I2V3F3|A0A7I2V3F3_HUMAN,tr|A0A7I2V428|A0A7I2V428_HUMAN,tr|A0A7I2V349|A0A7I2V349_HUMAN,tr|H7BY16|H7BY16_HUMAN,tr|A0A7I2V5M5|A0A7I2V5M5_HUMAN,tr|A0A7I2V2S8|A0A7I2V2S8_HUMAN,tr|C9JLB1|C9JLB1_HUMAN" 11 1655.7446 0.14 20360 21444 3 1655.745078 552.9222 Nucleolin OS=Homo sapiens OX=9606 GN=NCL PE=1 SV=3 3.83 3617.8 - 520529 - - - 0.2682 - 2.05 0.185 - 99.5 1 2 0 0.0004 14 0 0 0 4.63E+05 3.37E+06 - - - 2.5101 0.9377 221125_WJC_METTL3_EV_vs_WT_F02.21446.21446.3 0.00909 Sep-60 R.TMQELEIELQSQLSMK.A "sp|P19012|K1C15_HUMAN,tr|C9JTG5|C9JTG5_HUMAN,tr|A8MT21|A8MT21_HUMAN" 3 1906.938 3.53 20361 21446 3 1907.945503 636.6533 "Keratin, type I cytoskeletal 15 OS=Homo sapiens OX=9606 GN=KRT15 PE=1 SV=3" 4.25 3618 - 5.83E+06 - - - 528.3355 - 1.906 0.301 - 119.3 1 2 0 1.0075 16 0 0 0 4.17E+07 1.18E+07 - - - 3.2718 0.8566 221125_WJC_METTL3_EV_vs_WT_F02.21452.21452.2 1.06E-07 24-Oct A.EELPNYLVTLPAR.L sp|A8K2U0|A2ML1_HUMAN 1 1513.814 999 20366 21452 2 1513.805566 757.9143 Alpha-2-macroglobulin-like protein 1 OS=Homo sapiens OX=9606 GN=A2ML1 PE=1 SV=3 4.53 3618.4 - 3.66E+06 - - - -5.6004 - 2.202 0.58 - 422.5 1 1 0 -0.0085 13 0 0 0 1.12E+07 0.00E+00 - - - 5.3481 1 221125_WJC_METTL3_EV_vs_WT_F02.21453.21453.3 8.51E-07 17/68 R.GFGFITFTNPEHASVAMR[166.11].A sp|P98179|RBM3_HUMAN 1 1990.9599 1.03 20367 21453 3 1990.959741 664.6606 RNA-binding protein 3 OS=Homo sapiens OX=9606 GN=RBM3 PE=1 SV=1 6.75 3618.5 - 3.11E+06 - - - -0.0733 - 3.501 0.536 - 327.4 1 2 0 -0.0001 18 0 0 0 1.08E+08 1.04E+08 - - - 7.636 0.9613 221125_WJC_METTL3_EV_vs_WT_F02.21457.21457.2 3.38E-05 16/34 R.TIGTGLVTNTLAMTEEEK.N sp|P49411|EFTU_HUMAN 1 1906.9558 1.31 20371 21457 2 1907.953068 954.4852 "Elongation factor Tu, mitochondrial OS=Homo sapiens OX=9606 GN=TUFM PE=1 SV=2" 4.25 3618.9 - 1.92E+06 - - - 522.9849 - 3.173 0.347 - 667.4 1 2 0 0.9973 18 0 0 0 9.51E+07 7.26E+07 - - - 4.1296 1 221125_WJC_METTL3_EV_vs_WT_F02.21458.21458.3 3.92E-07 15/72 R.SSPAAFINPPIGTVTPALK.L "sp|Q9BY77|PDIP3_HUMAN,tr|F6VRR5|F6VRR5_HUMAN,tr|F8WCX5|F8WCX5_HUMAN,tr|Q6R954|Q6R954_HUMAN,tr|Q8WUT1|Q8WUT1_HUMAN,tr|F8WEE2|F8WEE2_HUMAN" 6 1880.0407 3.31 20372 21458 3 1880.042098 627.6875 Polymerase delta-interacting protein 3 OS=Homo sapiens OX=9606 GN=POLDIP3 PE=1 SV=2 8.47 3618.9 - 1.87E+06 - - - 0.717 - 2.825 0.489 - 264.4 1 2 0 0.0013 19 0 0 0 1.84E+07 5.55E+06 - - - 6.5429 0.9998 221125_WJC_METTL3_EV_vs_WT_F02.21462.21462.2 0.0058 24-Oct R.IITLTGPTNAIFK[136.11].A sp|Q15365|PCBP1_HUMAN 1 1395.8217 0.79 20376 21462 2 1395.821012 698.9181 Poly(rC)-binding protein 1 OS=Homo sapiens OX=9606 GN=PCBP1 PE=1 SV=2 8.75 3619.3 - 1.48E+06 - - - -0.4943 - 2.237 0.404 - 251.7 1 2 0 -0.0007 13 0 0 0 2.35E+07 2.97E+07 - - - 4.0911 0.9999 221125_WJC_METTL3_EV_vs_WT_F02.21465.21465.3 7.43E-05 14/52 R.WSSLAC[160.03]NIALDAVK[136.11].M "sp|P49368|TCPG_HUMAN,tr|Q5SZW8|Q5SZW8_HUMAN,tr|E9PRC8|E9PRC8_HUMAN,tr|B4DUR8|B4DUR8_HUMAN,tr|E9PQ35|E9PQ35_HUMAN,tr|Q5SZX6|Q5SZX6_HUMAN" 6 1554.7956 0.2 20379 21465 3 1554.793853 519.2725 T-complex protein 1 subunit gamma OS=Homo sapiens OX=9606 GN=CCT3 PE=1 SV=4 5.83 3619.6 - 1.35E+06 - - - -1.1005 - 2.325 0.39 - 253.4 1 2 0 -0.0017 14 0 0 0 2.76E+06 1.40E+07 - - - 5.1299 0.9999 221125_WJC_METTL3_EV_vs_WT_F02.21471.21471.2 2.63E-07 26-Nov K.FGYVDFESAEDLEK.A "sp|P19338|NUCL_HUMAN,tr|A0A7I2V506|A0A7I2V506_HUMAN,tr|A0A7I2V699|A0A7I2V699_HUMAN,tr|A0A7I2V2U7|A0A7I2V2U7_HUMAN,tr|A0A7I2V3F3|A0A7I2V3F3_HUMAN,tr|A0A7I2V428|A0A7I2V428_HUMAN,tr|A0A7I2V349|A0A7I2V349_HUMAN,tr|H7BY16|H7BY16_HUMAN,tr|A0A7I2V5M5|A0A7I2V5M5_HUMAN,tr|A0A7I2V2S8|A0A7I2V2S8_HUMAN,tr|C9JLB1|C9JLB1_HUMAN" 11 1647.7304 0.7 20384 21471 2 1647.728771 824.8725 Nucleolin OS=Homo sapiens OX=9606 GN=NCL PE=1 SV=3 3.83 3620.2 - 2.45E+07 - - - -1.0093 - 2.118 0.592 - 199.8 1 2 0 -0.0017 14 0 0 0 1.01E+08 1.44E+08 - - - 5.2963 1 221125_WJC_METTL3_EV_vs_WT_F02.21472.21472.2 3.01E-05 20-Nov R.THNLEPYFESF.L sp|P04264|K2C1_HUMAN 1 1382.6143 - 20385 21472 2 1382.613475 692.3144 "Keratin, type II cytoskeletal 1 OS=Homo sapiens OX=9606 GN=KRT1 PE=1 SV=6" 4.5 3620.3 - 1.49E+07 - - - -0.5837 - 2.479 0.593 - 414.6 1 1 0 -0.0008 11 0 0 0 - - - - - 5.8766 1 221125_WJC_METTL3_EV_vs_WT_F02.21473.21473.3 3.75E-08 21/68 R.GFGFITFTNPEHASVAMR.A sp|P98179|RBM3_HUMAN 1 1980.9516 1.03 20386 21473 3 1980.950138 661.3245 RNA-binding protein 3 OS=Homo sapiens OX=9606 GN=RBM3 PE=1 SV=1 6.75 3620.3 - 7.23E+06 - - - -0.7466 - 3.549 0.61 - 670.1 1 2 0 -0.0015 18 0 0 0 1.08E+08 1.04E+08 - - - 8.4946 0.9999 221125_WJC_METTL3_EV_vs_WT_F02.21478.21478.3 0.000285 13/36 R.LLFQNLWKPR.L "sp|O60573|IF4E2_HUMAN,tr|B8ZZL3|B8ZZL3_HUMAN" 2 1313.7608 1.82 20391 21478 3 1313.759885 438.9276 Eukaryotic translation initiation factor 4E type 2 OS=Homo sapiens OX=9606 GN=EIF4E2 PE=1 SV=1 11 3620.6 - 3.25E+06 - - - -0.717 - 2.532 0.407 - 313.2 1 2 0 -0.0009 10 0 0 0 3.38E+07 1.85E+07 - - - 5.7905 0.9895 221125_WJC_METTL3_EV_vs_WT_F02.21479.21479.2 2.53E-06 20-Nov Q.GLDPVEILQER[166.11].E "sp|P51531|SMCA2_HUMAN,sp|P51532|SMCA4_HUMAN,tr|A0A2R8Y7S2|A0A2R8Y7S2_HUMAN,tr|A0A0U1RRJ8|A0A0U1RRJ8_HUMAN,tr|A0A2R8YGG3|A0A2R8YGG3_HUMAN,tr|A0A0U1RQZ9|A0A0U1RQZ9_HUMAN,tr|Q9HBD4|Q9HBD4_HUMAN,tr|F6VDE0|F6VDE0_HUMAN,tr|A0A2R8YGP5|A0A2R8YGP5_HUMAN,tr|A0A2R8Y4P4|A0A2R8Y4P4_HUMAN" 10 1277.6855 0.84 20392 21479 2 1277.683537 639.85 Probable global transcription activator SNF2L2 OS=Homo sapiens OX=9606 GN=SMARCA2 PE=1 SV=2 4.14 3620.6 - 2.82E+06 - - - -1.5254 - 2.249 0.509 - 568 1 1 0 -0.0019 11 0 0 0 2.67E+07 3.19E+07 - - - 4.9924 0.9999 221125_WJC_METTL3_EV_vs_WT_F02.21480.21480.2 6.37E-08 24-Dec R.IITLTGPTNAIFK.A sp|Q15365|PCBP1_HUMAN 1 1387.8075 0.79 20393 21480 2 1387.805937 694.911 Poly(rC)-binding protein 1 OS=Homo sapiens OX=9606 GN=PCBP1 PE=1 SV=2 8.75 3620.7 - 2.75E+06 - - - -1.1277 - 2.309 0.547 - 450.6 1 2 0 -0.0016 13 0 0 0 2.35E+07 2.97E+07 - - - 5.2284 1 221125_WJC_METTL3_EV_vs_WT_F02.21481.21481.3 8.81E-06 20/56 R.FAPSPTGFLHLGGLR.T "sp|Q5JPH6|SYEM_HUMAN,tr|H3BTB7|H3BTB7_HUMAN" 2 1568.8463 1.74 20394 21481 3 1568.84508 523.9561 "Probable glutamate--tRNA ligase, mitochondrial OS=Homo sapiens OX=9606 GN=EARS2 PE=1 SV=2" 9.76 3620.7 - 2.62E+06 - - - -0.8076 - 3.755 0.563 - 403.9 1 2 0 -0.0013 15 0 0 0 2.14E+07 1.23E+07 - - - 8.269 0.9999 221125_WJC_METTL3_EV_vs_WT_F02.21482.21482.2 7.73E-06 22-Dec R.VFIGNLNTLVVK.K "sp|P0DMR1|HNRC4_HUMAN,sp|P07910|HNRPC_HUMAN,sp|O60812|HNRC1_HUMAN,sp|B2RXH8|HNRC2_HUMAN,sp|B7ZW38|HNRC3_HUMAN,tr|G3V251|G3V251_HUMAN,tr|B4DY08|B4DY08_HUMAN,tr|G3V575|G3V575_HUMAN,tr|B4DSU6|B4DSU6_HUMAN,tr|G3V3K6|G3V3K6_HUMAN,tr|B2R5W2|B2R5W2_HUMAN,tr|G3V4C1|G3V4C1_HUMAN,tr|A0A0G2JPF8|A0A0G2JPF8_HUMAN,tr|A0A0G2JNQ3|A0A0G2JNQ3_HUMAN,tr|G3V576|G3V576_HUMAN,tr|G3V5X6|G3V5X6_HUMAN,tr|G3V2H6|G3V2H6_HUMAN,tr|G3V4W0|G3V4W0_HUMAN,tr|G3V555|G3V555_HUMAN,tr|G3V4M8|G3V4M8_HUMAN,tr|G3V2Q1|G3V2Q1_HUMAN" 21 1315.7864 1.39 20395 21482 2 1315.786345 658.9005 Heterogeneous nuclear ribonucleoprotein C-like 4 OS=Homo sapiens OX=9606 GN=HNRNPCL4 PE=3 SV=1 8.72 3620.8 - 2.45E+06 - - - -0.0213 - 2.428 0.582 - 387.9 1 2 0 0 12 0 0 0 8.95E+07 6.45E+07 - - - 5.6737 1 221125_WJC_METTL3_EV_vs_WT_F02.21484.21484.3 4.06E-05 29/84 R.EALGLGPPAAQLTPPPAPVGLR[166.11].G "sp|Q8IY67|RAVR1_HUMAN,tr|E9PAU2|E9PAU2_HUMAN,tr|A0A087WZ13|A0A087WZ13_HUMAN" 3 2131.2029 1.03 20397 21484 3 2131.202825 711.4082 Ribonucleoprotein PTB-binding 1 OS=Homo sapiens OX=9606 GN=RAVER1 PE=1 SV=1 6.1 3621.1 - 2.29E+06 - - - -0.0328 - 3.831 0.384 - 669.3 1 2 0 -0.0001 22 0 0 0 2.08E+08 2.03E+08 - - - 6.0055 0.9999 221125_WJC_METTL3_EV_vs_WT_F02.21485.21485.2 0.000596 13/26 K.FLFDSVSSQNVGLR[166.11].E "sp|O00410|IPO5_HUMAN,tr|H0Y3V4|H0Y3V4_HUMAN,tr|E7ETV3|E7ETV3_HUMAN,tr|H0Y8C6|H0Y8C6_HUMAN" 4 1577.8077 1.2 20398 21485 2 1577.808097 789.9111 Importin-5 OS=Homo sapiens OX=9606 GN=IPO5 PE=1 SV=4 5.84 3621.1 - 2.25E+06 - - - 0.2345 - 2.74 0.553 - 384.9 1 2 0 0.0004 14 0 0 0 1.00E+07 8.32E+06 - - - 5.6548 1 221125_WJC_METTL3_EV_vs_WT_F02.21486.21486.3 3.11E-05 16/36 R.LLFQNLWK[136.11]PR[166.11].L "sp|O60573|IF4E2_HUMAN,tr|B8ZZL3|B8ZZL3_HUMAN" 2 1331.7833 1.82 20399 21486 3 1331.782702 444.935 Eukaryotic translation initiation factor 4E type 2 OS=Homo sapiens OX=9606 GN=EIF4E2 PE=1 SV=1 11 3621.2 - 1.90E+06 - - - -0.4468 - 2.597 0.486 - 449 1 2 0 -0.0006 10 0 0 0 3.38E+07 1.85E+07 - - - 6.7454 1 221125_WJC_METTL3_EV_vs_WT_F02.21487.21487.3 8.20E-07 18/72 R.SSPAAFINPPIGTVTPALK[136.11].L "sp|Q9BY77|PDIP3_HUMAN,tr|F6VRR5|F6VRR5_HUMAN,tr|F8WCX5|F8WCX5_HUMAN,tr|Q6R954|Q6R954_HUMAN,tr|Q8WUT1|Q8WUT1_HUMAN,tr|F8WEE2|F8WEE2_HUMAN" 6 1888.0549 1.16 20400 21487 3 1888.055026 630.3589 Polymerase delta-interacting protein 3 OS=Homo sapiens OX=9606 GN=POLDIP3 PE=1 SV=2 8.47 3621.3 - 1.69E+06 - - - 0.0403 - 2.847 0.473 - 408.1 1 2 0 0.0001 19 0 0 0 5.91E+07 5.09E+07 - - - 6.3839 1 221125_WJC_METTL3_EV_vs_WT_F02.21488.21488.3 1.14E-08 23/56 R.FAPSPTGFLHLGGLR[166.11].T "sp|Q5JPH6|SYEM_HUMAN,tr|H3BTB7|H3BTB7_HUMAN" 2 1578.8546 2.06 20401 21488 3 1578.858183 527.2921 "Probable glutamate--tRNA ligase, mitochondrial OS=Homo sapiens OX=9606 GN=EARS2 PE=1 SV=2" 9.76 3621.4 - 1.59E+06 - - - 2.2586 - 3.924 0.608 - 657 1 2 0 0.0036 15 0 0 0 1.70E+07 8.22E+06 - - - 8.8849 0.9987 221125_WJC_METTL3_EV_vs_WT_F02.21490.21490.2 0.000512 22-Nov K.TPLPPELADVQA.- "sp|Q9Y5V0|ZN706_HUMAN,tr|H0YC70|H0YC70_HUMAN" 2 1249.6554 - 20402 21490 2 1249.658514 625.835 Zinc finger protein 706 OS=Homo sapiens OX=9606 GN=ZNF706 PE=1 SV=1 3.67 3621.6 - 1.07E+06 - - - 2.4775 - 1.907 0.343 - 322.9 1 2 0 0.0031 12 0 0 0 - - - - - 3.2719 0.91 221125_WJC_METTL3_EV_vs_WT_F02.21493.21493.2 0.0928 22-Aug R.NVQALEIELQSQ.L "sp|P13645|K1C10_HUMAN,tr|A0A1B0GVI3|A0A1B0GVI3_HUMAN" 2 1370.7042 - 20405 21493 2 1370.70178 686.3594 "Keratin, type I cytoskeletal 10 OS=Homo sapiens OX=9606 GN=KRT10 PE=1 SV=6" 3.79 3621.7 - 1.07E+07 - - - -1.7356 - 1.648 0.284 - 220.6 1 1 0 -0.0024 12 0 0 0 - - - - - 2.4523 0.9998 221125_WJC_METTL3_EV_vs_WT_F02.21497.21497.3 0.209 17/52 K.LLEQALVIEEQLR[166.11]R[166.11].A "sp|Q14839|CHD4_HUMAN,sp|Q8TDI0|CHD5_HUMAN,sp|Q12873|CHD3_HUMAN,tr|A0A2R8Y4X2|A0A2R8Y4X2_HUMAN,tr|A0A2U3TZM0|A0A2U3TZM0_HUMAN,tr|H7C0J3|H7C0J3_HUMAN,tr|A0A2R8YD40|A0A2R8YD40_HUMAN,tr|A0A2R8Y5J0|A0A2R8Y5J0_HUMAN,tr|A0A2R8Y425|A0A2R8Y425_HUMAN,tr|A0A2R8YFK9|A0A2R8YFK9_HUMAN,tr|A0A0C4DGG9|A0A0C4DGG9_HUMAN,tr|A0A2R8YFD8|A0A2R8YFD8_HUMAN,tr|A0A2R8YDW2|A0A2R8YDW2_HUMAN,tr|A0A2R8Y7I0|A0A2R8Y7I0_HUMAN,tr|F5GWX5|F5GWX5_HUMAN,tr|A0A2R8Y7M9|A0A2R8Y7M9_HUMAN,tr|I3L229|I3L229_HUMAN,tr|A0A2R8Y521|A0A2R8Y521_HUMAN,tr|A0A2R8YDJ9|A0A2R8YDJ9_HUMAN,tr|A0A2R8Y212|A0A2R8Y212_HUMAN,tr|H7C3H7|H7C3H7_HUMAN" 21 1729.0001 0.93 20409 21497 3 1729.000448 577.3406 Chromodomain-helicase-DNA-binding protein 4 OS=Homo sapiens OX=9606 GN=CHD4 PE=1 SV=2 4.79 3622 - 2.45E+06 - - - 0.1961 - 2.886 0.304 - 404.9 1 2 0 0.0003 14 0 0 0 7.05E+06 7.56E+06 - - - 4.7459 0.9999 221125_WJC_METTL3_EV_vs_WT_F02.21498.21498.3 2.74E-05 15/44 R.WLLYHELVLTTK.E "sp|O60231|DHX16_HUMAN,tr|Q5SQH5|Q5SQH5_HUMAN,tr|A0A140T8Y5|A0A140T8Y5_HUMAN" 3 1514.8497 1.26 20410 21498 3 1514.852626 505.9572 Pre-mRNA-splicing factor ATP-dependent RNA helicase DHX16 OS=Homo sapiens OX=9606 GN=DHX16 PE=1 SV=2 6.75 3622.1 - 2.27E+06 - - - 1.9309 - 2.815 0.467 - 297 1 2 0 0.0029 12 0 0 0 7.55E+06 5.99E+06 - - - 6.6145 1 221125_WJC_METTL3_EV_vs_WT_F02.21503.21503.2 2.44E-06 15/26 K.FLFDSVSSQNVGLR.E "sp|O00410|IPO5_HUMAN,tr|H0Y3V4|H0Y3V4_HUMAN,tr|E7ETV3|E7ETV3_HUMAN,tr|H0Y8C6|H0Y8C6_HUMAN" 4 1567.7995 1.2 20415 21503 2 1567.798666 784.907 Importin-5 OS=Homo sapiens OX=9606 GN=IPO5 PE=1 SV=4 5.84 3622.7 - 1.46E+06 - - - -0.5045 - 2.975 0.649 - 803.3 1 2 0 -0.0008 14 0 0 0 1.00E+07 8.32E+06 - - - 6.5702 1 221125_WJC_METTL3_EV_vs_WT_F02.21506.21506.2 5.06E-07 14/24 K.WGTPVPLEGFEDK[136.11].V sp|P56192|SYMC_HUMAN 1 1481.7282 -1 20418 21506 2 1481.721154 741.8714 "Methionine--tRNA ligase, cytoplasmic OS=Homo sapiens OX=9606 GN=MARS1 PE=1 SV=2" 4.14 3623 - 1.04E+06 - - - -4.7526 - 2.735 0.604 - 610.8 1 2 0 -0.007 13 0 0 0 0.00E+00 0.00E+00 - - - 6.0822 0.8822 221125_WJC_METTL3_EV_vs_WT_F02.21509.21509.2 9.67E-06 13/24 V.ALVMLQEDELLSK.M sp|Q96A49|SYAP1_HUMAN 1 1487.7905 1.71 20421 21509 2 1487.798124 744.9025 Synapse-associated protein 1 OS=Homo sapiens OX=9606 GN=SYAP1 PE=1 SV=1 4.14 3623.4 - 758813 - - - 5.1029 - 2.834 0.464 - 544.6 1 1 0 0.0076 13 0 0 0 4.20E+06 2.46E+06 - - - 5.1392 0.9988 221125_WJC_METTL3_EV_vs_WT_F02.21514.21514.2 3.11E-07 22-Dec K.GAEADQIIEYLK[136.11].Q "sp|Q12904|AIMP1_HUMAN,tr|A0A804HJ47|A0A804HJ47_HUMAN,tr|D6R937|D6R937_HUMAN,tr|A0A5F9ZHC5|A0A5F9ZHC5_HUMAN" 4 1356.7016 2.63 20425 21514 2 1356.696759 679.3581 Aminoacyl tRNA synthase complex-interacting multifunctional protein 1 OS=Homo sapiens OX=9606 GN=AIMP1 PE=1 SV=2 4.14 3623.8 - 4.69E+06 - - - -3.6029 - 2.554 0.375 - 654.6 1 2 0 -0.0049 12 0 0 0 7.03E+07 2.67E+07 - - - 4.2764 0.9998 221125_WJC_METTL3_EV_vs_WT_F02.21515.21515.2 0.00308 20-Nov K.LDPSIFESLQK.E "sp|Q9Y265|RUVB1_HUMAN,tr|E7ETR0|E7ETR0_HUMAN" 2 1275.6711 0.68 20426 21515 2 1275.671702 638.8428 RuvB-like 1 OS=Homo sapiens OX=9606 GN=RUVBL1 PE=1 SV=1 4.37 3623.9 - 4.27E+06 - - - 0.497 - 1.98 0.418 - 347.9 1 2 0 0.0006 11 0 0 0 4.29E+07 6.31E+07 - - - 3.9761 1 221125_WJC_METTL3_EV_vs_WT_F02.21516.21516.3 7.27E-07 21/84 R.EALGLGPPAAQLTPPPAPVGLR.G "sp|Q8IY67|RAVR1_HUMAN,tr|E9PAU2|E9PAU2_HUMAN,tr|A0A087WZ13|A0A087WZ13_HUMAN" 3 2121.1946 1.03 20427 21516 3 2121.196098 708.0722 Ribonucleoprotein PTB-binding 1 OS=Homo sapiens OX=9606 GN=RAVER1 PE=1 SV=1 6.1 3623.9 - 4.23E+06 - - - 0.6944 - 3.441 0.542 - 294.8 1 2 0 0.0015 22 0 0 0 2.08E+08 2.03E+08 - - - 7.5121 0.9998 221125_WJC_METTL3_EV_vs_WT_F02.21517.21517.2 0.000373 22-Sep R.NIPGITLLNVSK.L "sp|P36578|RL4_HUMAN,tr|H3BM89|H3BM89_HUMAN" 2 1267.75 1.07 20428 21517 2 1267.749518 634.8823 60S ribosomal protein L4 OS=Homo sapiens OX=9606 GN=RPL4 PE=1 SV=5 8.75 3624 - 3.83E+06 - - - -0.3699 - 2.036 0.474 - 169.7 1 2 0 -0.0005 12 0 0 0 3.55E+07 3.32E+07 - - - 4.4125 1 221125_WJC_METTL3_EV_vs_WT_F02.21519.21519.3 5.97E-06 13/56 K.EAAASGLPLMVIIHK[136.11].S sp|O95881|TXD12_HUMAN 1 1556.884 1.22 20430 21519 3 1556.883442 519.9686 Thioredoxin domain-containing protein 12 OS=Homo sapiens OX=9606 GN=TXNDC12 PE=1 SV=1 6.85 3624.1 - 1.71E+06 - - - -0.3488 - 2.466 0.504 - 272.1 1 2 0 -0.0005 15 0 0 0 4.88E+07 4.01E+07 - - - 6.5142 0.9999 221125_WJC_METTL3_EV_vs_WT_F02.21521.21521.3 3.24E-05 14/56 K.EAAASGLPLMVIIHK.S sp|O95881|TXD12_HUMAN 1 1548.8698 1.2 20432 21521 3 1548.870328 517.2972 Thioredoxin domain-containing protein 12 OS=Homo sapiens OX=9606 GN=TXNDC12 PE=1 SV=1 6.85 3624.3 - 1.58E+06 - - - 0.3506 - 2.494 0.431 - 304.5 1 2 0 0.0005 15 0 0 0 4.79E+07 3.98E+07 - - - 5.7297 0.9998 221125_WJC_METTL3_EV_vs_WT_F02.21522.21522.2 0.00315 14/24 K.IWDLQGSEEPVFR.A "sp|Q6RFH5|WDR74_HUMAN,tr|E9PS41|E9PS41_HUMAN" 2 1574.7729 2.85 20433 21522 2 1574.774915 788.3937 WD repeat-containing protein 74 OS=Homo sapiens OX=9606 GN=WDR74 PE=1 SV=1 4.14 3624.4 - 1.51E+06 - - - 1.2745 - 2.586 0.442 - 818.2 1 2 0 0.002 13 0 0 0 5.00E+06 1.75E+06 - - - 4.7435 0.9999 221125_WJC_METTL3_EV_vs_WT_F02.21524.21524.2 0.000166 13/20 K.VTGEVLDILTR[166.11].L "sp|O75955|FLOT1_HUMAN,tr|A0A140T9W4|A0A140T9W4_HUMAN,tr|A0A140T9R1|A0A140T9R1_HUMAN,tr|A0A140T974|A0A140T974_HUMAN" 4 1224.6953 1.53 20435 21524 2 1224.69547 613.3549 Flotillin-1 OS=Homo sapiens OX=9606 GN=FLOT1 PE=1 SV=3 4.37 3624.6 - 1.25E+06 - - - 0.12 - 2.674 0.521 - 907.1 1 2 0 0.0001 11 0 0 0 3.65E+07 2.39E+07 - - - 5.5499 0.9999 221125_WJC_METTL3_EV_vs_WT_F02.21525.21525.2 7.07E-08 20-Nov R.FFDEESYSLLR.K "sp|P51571|SSRD_HUMAN,tr|A6NLM8|A6NLM8_HUMAN" 2 1404.6561 0.84 20436 21525 2 1404.65422 703.3353 Translocon-associated protein subunit delta OS=Homo sapiens OX=9606 GN=SSR4 PE=1 SV=1 4.14 3624.7 - 982606 - - - -1.3712 - 2.23 0.576 - 252.6 1 2 0 -0.0019 11 0 0 0 4.68E+06 5.55E+06 - - - 5.4643 0.9839 221125_WJC_METTL3_EV_vs_WT_F02.21532.21532.3 0.537 Aug-60 R.VPILK[136.11]PMDLMVEASPR[166.11].R sp|Q66LE6|2ABD_HUMAN 1 1812.9961 1.97 20442 21532 3 1812.99626 605.3393 Serine\threonine-protein phosphatase 2A 55 kDa regulatory subunit B delta isoform OS=Homo sapiens OX=9606 GN=PPP2R2D PE=1 SV=1 6.04 3625.7 - 595202 - - - 0.1059 - 1.614 0.157 - 47.8 1 2 0 0.0002 16 0 0 0 5.16E+06 2.62E+06 - - - 1.5187 0.9999 221125_WJC_METTL3_EV_vs_WT_F02.21533.21533.2 1.67E-09 20/42 R.EALGLGPPAAQLTPPPAPVGLR[166.11].G "sp|Q8IY67|RAVR1_HUMAN,tr|E9PAU2|E9PAU2_HUMAN,tr|A0A087WZ13|A0A087WZ13_HUMAN" 3 2131.2029 1.22 20443 21533 2 2131.204892 1066.6087 Ribonucleoprotein PTB-binding 1 OS=Homo sapiens OX=9606 GN=RAVER1 PE=1 SV=1 6.1 3625.8 - 1.01E+06 - - - 0.937 - 3.509 0.478 - 481.9 1 2 0 0.002 22 0 0 0 2.90E+07 2.38E+07 - - - 5.6572 0.9999 221125_WJC_METTL3_EV_vs_WT_F02.21534.21534.2 4.26E-05 13/28 K.GFGFVTFENSADADR.A "sp|O43251|RFOX2_HUMAN,sp|Q9NWB1|RFOX1_HUMAN,tr|A0A6Q8PGE0|A0A6Q8PGE0_HUMAN,tr|A0A6Q8PH77|A0A6Q8PH77_HUMAN,tr|A0A286YEU2|A0A286YEU2_HUMAN,tr|A0A087X2B1|A0A087X2B1_HUMAN,tr|F8VR27|F8VR27_HUMAN,tr|B7Z1U7|B7Z1U7_HUMAN,tr|B0QYV1|B0QYV1_HUMAN,tr|A0A6Q8PHA3|A0A6Q8PHA3_HUMAN,tr|F8VZY7|F8VZY7_HUMAN,tr|B0QYY4|B0QYY4_HUMAN,tr|J3KNW3|J3KNW3_HUMAN,tr|F8VZG9|F8VZG9_HUMAN,tr|F8VRS4|F8VRS4_HUMAN,tr|A0A6Q8PFM4|A0A6Q8PFM4_HUMAN,tr|S4R469|S4R469_HUMAN,tr|A0A804HKG7|A0A804HKG7_HUMAN,tr|A0A0G2JRD1|A0A0G2JRD1_HUMAN,tr|A0A0G2JRA5|A0A0G2JRA5_HUMAN,tr|A0A804HJM2|A0A804HJM2_HUMAN,tr|I3L1D4|I3L1D4_HUMAN,tr|B0QYY7|B0QYY7_HUMAN,tr|A0A0G2JSB3|A0A0G2JSB3_HUMAN,tr|S4R3K7|S4R3K7_HUMAN" 25 1631.7216 1.21 20444 21534 2 1631.720526 816.8681 RNA binding protein fox-1 homolog 2 OS=Homo sapiens OX=9606 GN=RBFOX2 PE=1 SV=3 4.03 3625.9 - 1.81E+07 - - - -0.6582 - 3.028 0.494 - 452.7 1 2 0 -0.0011 15 0 0 0 1.46E+09 1.20E+09 - - - 5.4132 0.9987 221125_WJC_METTL3_EV_vs_WT_F02.21535.21535.2 0.000543 14/22 K.GAEADQIIEYLK.Q "sp|Q12904|AIMP1_HUMAN,tr|A0A804HJ47|A0A804HJ47_HUMAN,tr|D6R937|D6R937_HUMAN,tr|A0A5F9ZHC5|A0A5F9ZHC5_HUMAN" 4 1348.6874 2.6 20445 21535 2 1348.682354 675.351 Aminoacyl tRNA synthase complex-interacting multifunctional protein 1 OS=Homo sapiens OX=9606 GN=AIMP1 PE=1 SV=2 4.14 3625.9 - 1.23E+07 - - - -3.7763 - 2.901 0.335 - 849.3 1 2 0 -0.0051 12 0 0 0 7.10E+07 2.73E+07 - - - 4.3161 1 221125_WJC_METTL3_EV_vs_WT_F02.21536.21536.2 2.26E-09 14/28 K.GFGFVC[160.03]FSSPEEATK[136.11].A "sp|Q13310|PABP4_HUMAN,sp|Q9H361|PABP3_HUMAN,sp|Q4VXU2|PAP1L_HUMAN,sp|P11940|PABP1_HUMAN,tr|A0A7I2V5W9|A0A7I2V5W9_HUMAN,tr|H0YEU6|H0YEU6_HUMAN,tr|A0A7I2YQE4|A0A7I2YQE4_HUMAN,tr|A0A7I2V649|A0A7I2V649_HUMAN,tr|B1ANR0|B1ANR0_HUMAN,tr|A0A6Q8JFT6|A0A6Q8JFT6_HUMAN,tr|A0A7I2V4L7|A0A7I2V4L7_HUMAN,tr|H0YB86|H0YB86_HUMAN,tr|H0YAR2|H0YAR2_HUMAN,tr|E7ERJ7|E7ERJ7_HUMAN,tr|A0A7I2V598|A0A7I2V598_HUMAN,tr|A0A7I2YQ88|A0A7I2YQ88_HUMAN,tr|A0A7I2V4V6|A0A7I2V4V6_HUMAN,tr|H0Y5F5|H0Y5F5_HUMAN,tr|A0A6I8PS38|A0A6I8PS38_HUMAN,tr|A0A6I8PLA1|A0A6I8PLA1_HUMAN,tr|A0A087WTT1|A0A087WTT1_HUMAN,tr|A0A7I2YQ90|A0A7I2YQ90_HUMAN,tr|A0A7I2V4N4|A0A7I2V4N4_HUMAN,tr|E7EQV3|E7EQV3_HUMAN" 24 1669.7538 1.48 20446 21536 2 1669.751412 835.8842 Polyadenylate-binding protein 4 OS=Homo sapiens OX=9606 GN=PABPC4 PE=1 SV=1 4.53 3626 - 3.53E+06 - - - -1.4056 - 2.87 0.685 - 790.1 1 2 0 -0.0023 15 0 0 0 2.18E+08 1.47E+08 - - - 6.6917 0.9897 221125_WJC_METTL3_EV_vs_WT_F02.21538.21538.2 1.52 28-Aug R.NINSSC[160.03]R[166.11]PGPGAWLR.V sp|O95479|G6PE_HUMAN 1 1693.8346 - 20448 21538 2 1693.833471 847.9246 GDH\6PGL endoplasmic bifunctional protein OS=Homo sapiens OX=9606 GN=H6PD PE=1 SV=2 10.35 3626.1 - 2.67E+06 - - - -0.6825 - 1.497 0.101 - 121.7 2 2 0 -0.0012 15 0 0 0 - - - - - 0.6441 1 221125_WJC_METTL3_EV_vs_WT_F02.21540.21540.2 2.17E-11 14/30 R.ASTNAMLISAGLPPLK.A sp|O43143|DHX15_HUMAN 1 1582.8753 0.86 20450 21540 2 1582.873873 792.4449 Pre-mRNA-splicing factor ATP-dependent RNA helicase DHX15 OS=Homo sapiens OX=9606 GN=DHX15 PE=1 SV=2 8.8 3626.2 - 2.06E+06 - - - -0.8788 - 2.737 0.612 - 381.9 1 2 0 -0.0014 16 0 0 0 2.13E+07 2.46E+07 - - - 6.0362 0.9999 221125_WJC_METTL3_EV_vs_WT_F02.21541.21541.2 1.91E-05 13/22 K.LDISDEFSEAIK.A sp|Q9H223|EHD4_HUMAN 1 1365.6664 0.74 20451 21541 2 1365.666831 683.8405 EH domain-containing protein 4 OS=Homo sapiens OX=9606 GN=EHD4 PE=1 SV=1 3.92 3626.3 - 1.98E+06 - - - 0.3324 - 2.762 0.512 - 713 1 2 0 0.0005 12 0 0 0 1.77E+07 2.41E+07 - - - 5.4956 0.9764 221125_WJC_METTL3_EV_vs_WT_F02.21545.21545.2 0.000377 28-Sep R.VLQC[160.03]QEEELTQMVST.M "sp|Q8N5Z5|KCD17_HUMAN,sp|Q9NXV2|KCTD5_HUMAN,sp|Q14681|KCTD2_HUMAN,tr|A0A087WX35|A0A087WX35_HUMAN,tr|H0Y731|H0Y731_HUMAN" 5 1793.8176 - 20455 21545 2 1793.814965 897.9161 BTB\POZ domain-containing protein KCTD17 OS=Homo sapiens OX=9606 GN=KCTD17 PE=1 SV=3 3.67 3626.7 - 1.14E+06 - - - -1.4416 - 1.708 0.454 - 136.4 1 1 0 -0.0026 15 0 0 0 - - - - - 3.7095 1 221125_WJC_METTL3_EV_vs_WT_F02.21549.21549.2 1.20E-06 20/42 R.EALGLGPPAAQLTPPPAPVGLR.G "sp|Q8IY67|RAVR1_HUMAN,tr|E9PAU2|E9PAU2_HUMAN,tr|A0A087WZ13|A0A087WZ13_HUMAN" 3 2121.1946 1.2 20459 21549 2 2121.195032 1061.6046 Ribonucleoprotein PTB-binding 1 OS=Homo sapiens OX=9606 GN=RAVER1 PE=1 SV=1 6.1 3627.2 - 625410 - - - 0.1919 - 3.621 0.523 - 437.3 1 2 0 0.0004 22 0 0 0 3.03E+07 2.54E+07 - - - 6.0673 1 221125_WJC_METTL3_EV_vs_WT_F02.21550.21550.2 5.11E-10 13/34 R.GFGFITFTNPEHASVAMR[166.11].A sp|P98179|RBM3_HUMAN 1 1990.9599 1.11 20460 21550 2 1990.95739 996.4872 RNA-binding protein 3 OS=Homo sapiens OX=9606 GN=RBM3 PE=1 SV=1 6.75 3627.4 - 521087 - - - -1.2542 - 3.145 0.626 - 536 1 2 0 -0.0025 18 0 0 0 3.16E+06 2.86E+06 - - - 6.4809 1 221125_WJC_METTL3_EV_vs_WT_F02.21551.21551.3 7.31E-08 17/48 M.C[160.03]GIFAYLNYHVPR.T "sp|Q06210|GFPT1_HUMAN,tr|A0A6I8PTT9|A0A6I8PTT9_HUMAN,tr|A0A6I8PRT6|A0A6I8PRT6_HUMAN" 3 1608.7871 0.52 20461 21551 3 1608.788095 537.2696 Glutamine--fructose-6-phosphate aminotransferase [isomerizing] 1 OS=Homo sapiens OX=9606 GN=GFPT1 PE=1 SV=3 8.21 3627.5 - 466688 - - - 0.6073 - 3.313 0.591 - 422.5 1 2 0 0.001 13 0 0 0 3.84E+06 7.44E+06 - - - 8.3765 0.9998 221125_WJC_METTL3_EV_vs_WT_F02.21553.21553.3 0.000268 16/52 K.AVAEQIPLLVQGVR[166.11].G sp|Q9Y490|TLN1_HUMAN 1 1501.8856 1.37 20462 21553 3 1501.885114 501.6358 Talin-1 OS=Homo sapiens OX=9606 GN=TLN1 PE=1 SV=3 6.05 3627.7 - 453547 - - - -0.3123 - 2.55 0.333 - 389.3 1 2 0 -0.0005 14 0 0 0 6.17E+06 4.51E+06 - - - 4.7402 1 221125_WJC_METTL3_EV_vs_WT_F02.21555.21555.2 2.15E-06 14/24 R.IVDDWANDGWGLK.K "sp|P27824|CALX_HUMAN,tr|A0A7P0T937|A0A7P0T937_HUMAN,tr|A0A7P0T840|A0A7P0T840_HUMAN,tr|A0A7P0TB65|A0A7P0TB65_HUMAN,tr|A0A7P0TAE9|A0A7P0TAE9_HUMAN,tr|D6RGY2|D6RGY2_HUMAN,tr|A0A7P0T8G1|A0A7P0T8G1_HUMAN,tr|A0A7P0Z4D6|A0A7P0Z4D6_HUMAN,tr|A0A7P0T9L0|A0A7P0T9L0_HUMAN" 9 1487.7045 1.34 20463 21555 2 1487.705477 744.8595 Calnexin OS=Homo sapiens OX=9606 GN=CANX PE=1 SV=2 3.93 3627.9 - 4.49E+06 - - - 0.6607 - 2.847 0.602 - 569.2 1 2 0 0.001 13 0 0 0 8.58E+07 6.43E+07 - - - 6.1723 0.9999 221125_WJC_METTL3_EV_vs_WT_F02.21556.21556.2 5.62E-07 24-Oct R.IVDDWANDGWGLK[136.11].K "sp|P27824|CALX_HUMAN,tr|A0A7P0T937|A0A7P0T937_HUMAN,tr|A0A7P0T840|A0A7P0T840_HUMAN,tr|A0A7P0TB65|A0A7P0TB65_HUMAN,tr|A0A7P0TAE9|A0A7P0TAE9_HUMAN,tr|D6RGY2|D6RGY2_HUMAN,tr|A0A7P0T8G1|A0A7P0T8G1_HUMAN,tr|A0A7P0Z4D6|A0A7P0Z4D6_HUMAN,tr|A0A7P0T9L0|A0A7P0T9L0_HUMAN" 9 1495.7187 1.34 20464 21556 2 1495.718337 748.8666 Calnexin OS=Homo sapiens OX=9606 GN=CANX PE=1 SV=2 3.93 3628 - 3.13E+06 - - - -0.2387 - 2.38 0.581 - 188.3 1 2 0 -0.0004 13 0 0 0 8.58E+07 6.43E+07 - - - 5.5576 0.9999 221125_WJC_METTL3_EV_vs_WT_F02.21559.21559.3 1.66E-06 13/56 K.GFGFVTFENSADADR.A "sp|O43251|RFOX2_HUMAN,sp|Q9NWB1|RFOX1_HUMAN,tr|A0A6Q8PGE0|A0A6Q8PGE0_HUMAN,tr|A0A6Q8PH77|A0A6Q8PH77_HUMAN,tr|A0A286YEU2|A0A286YEU2_HUMAN,tr|A0A087X2B1|A0A087X2B1_HUMAN,tr|F8VR27|F8VR27_HUMAN,tr|B7Z1U7|B7Z1U7_HUMAN,tr|B0QYV1|B0QYV1_HUMAN,tr|A0A6Q8PHA3|A0A6Q8PHA3_HUMAN,tr|F8VZY7|F8VZY7_HUMAN,tr|B0QYY4|B0QYY4_HUMAN,tr|J3KNW3|J3KNW3_HUMAN,tr|F8VZG9|F8VZG9_HUMAN,tr|F8VRS4|F8VRS4_HUMAN,tr|A0A6Q8PFM4|A0A6Q8PFM4_HUMAN,tr|S4R469|S4R469_HUMAN,tr|A0A804HKG7|A0A804HKG7_HUMAN,tr|A0A0G2JRD1|A0A0G2JRD1_HUMAN,tr|A0A0G2JRA5|A0A0G2JRA5_HUMAN,tr|A0A804HJM2|A0A804HJM2_HUMAN,tr|I3L1D4|I3L1D4_HUMAN,tr|B0QYY7|B0QYY7_HUMAN,tr|A0A0G2JSB3|A0A0G2JSB3_HUMAN,tr|S4R3K7|S4R3K7_HUMAN" 25 1631.7216 1.2 20467 21559 3 1631.716928 544.9145 RNA binding protein fox-1 homolog 2 OS=Homo sapiens OX=9606 GN=RBFOX2 PE=1 SV=3 4.03 3628.1 - 1.85E+06 - - - -2.8632 - 2.029 0.523 - 160.7 1 2 0 -0.0047 15 0 0 0 2.54E+07 2.11E+07 - - - 6.2159 1 221125_WJC_METTL3_EV_vs_WT_F02.21562.21562.2 5.04E-13 15/30 R.FVDEGSLYGLSIATSR.N "sp|Q9Y5J1|UTP18_HUMAN,tr|J3QRG0|J3QRG0_HUMAN,tr|J3QR85|J3QR85_HUMAN,tr|J3KSR7|J3KSR7_HUMAN,tr|J3QLD6|J3QLD6_HUMAN" 5 1713.8574 1.78 20470 21562 2 1713.858419 857.936 U3 small nucleolar RNA-associated protein 18 homolog OS=Homo sapiens OX=9606 GN=UTP18 PE=1 SV=3 4.37 3628.4 - 1.09E+06 - - - 0.6144 - 3.017 0.666 - 633.6 1 2 0 0.0011 16 0 0 0 1.36E+07 7.66E+06 - - - 6.6746 0.9998 221125_WJC_METTL3_EV_vs_WT_F02.21563.21563.3 0.0135 Nov-36 R.TSIVHLFEWR.W "sp|P0DTE8|AMY1C_HUMAN,sp|P0DTE7|AMY1B_HUMAN,sp|P04746|AMYP_HUMAN,sp|P0DUB6|AMY1A_HUMAN,sp|P19961|AMY2B_HUMAN,tr|H7BZQ8|H7BZQ8_HUMAN,tr|Q5T084|Q5T084_HUMAN,tr|C9JWK7|C9JWK7_HUMAN,tr|A0A804HHZ3|A0A804HHZ3_HUMAN,tr|C9J2Z5|C9J2Z5_HUMAN" 10 1286.6772 140.9 20471 21563 3 1286.676683 429.8997 Alpha-amylase 1C OS=Homo sapiens OX=9606 GN=AMY1C PE=1 SV=1 6.41 3628.5 - 1.04E+06 - - - -0.3684 - 2.231 0.343 - 270.9 1 2 0 -0.0005 10 0 0 0 8.47E+06 6.01E+04 - - - 4.7075 0.9865 221125_WJC_METTL3_EV_vs_WT_F02.21565.21565.2 4.80E-06 15/28 S.LLQPLNVEIDPEIQK.V sp|P04264|K2C1_HUMAN 1 1747.972 999 20473 21565 2 1747.975468 874.9933 "Keratin, type II cytoskeletal 1 OS=Homo sapiens OX=9606 GN=KRT1 PE=1 SV=6" 4.14 3628.8 - 968073 - - - 1.9834 - 2.861 0.49 - 593.1 1 1 0 0.0035 15 0 0 0 2.61E+07 0.00E+00 - - - 5.2434 0.9135 221125_WJC_METTL3_EV_vs_WT_F02.21566.21566.3 0.000885 15/56 S.LLQPLNVEIDPEIQK.V sp|P04264|K2C1_HUMAN 1 1747.972 999 20474 21566 3 1747.978538 583.6646 "Keratin, type II cytoskeletal 1 OS=Homo sapiens OX=9606 GN=KRT1 PE=1 SV=6" 4.14 3628.9 - 925652 - - - 3.7398 - 2.695 0.339 - 282.3 1 1 0 0.0065 15 0 0 0 9.46E+06 0.00E+00 - - - 4.9046 1 221125_WJC_METTL3_EV_vs_WT_F02.21571.21571.2 1.65E-11 14/28 K.GFGFVTFENSADADR[166.11].A "sp|O43251|RFOX2_HUMAN,sp|Q9NWB1|RFOX1_HUMAN,tr|A0A6Q8PGE0|A0A6Q8PGE0_HUMAN,tr|A0A6Q8PH77|A0A6Q8PH77_HUMAN,tr|A0A286YEU2|A0A286YEU2_HUMAN,tr|A0A087X2B1|A0A087X2B1_HUMAN,tr|F8VR27|F8VR27_HUMAN,tr|B7Z1U7|B7Z1U7_HUMAN,tr|B0QYV1|B0QYV1_HUMAN,tr|A0A6Q8PHA3|A0A6Q8PHA3_HUMAN,tr|F8VZY7|F8VZY7_HUMAN,tr|B0QYY4|B0QYY4_HUMAN,tr|J3KNW3|J3KNW3_HUMAN,tr|F8VZG9|F8VZG9_HUMAN,tr|F8VRS4|F8VRS4_HUMAN,tr|A0A6Q8PFM4|A0A6Q8PFM4_HUMAN,tr|S4R469|S4R469_HUMAN,tr|A0A804HKG7|A0A804HKG7_HUMAN,tr|A0A0G2JRD1|A0A0G2JRD1_HUMAN,tr|A0A0G2JRA5|A0A0G2JRA5_HUMAN,tr|A0A804HJM2|A0A804HJM2_HUMAN,tr|I3L1D4|I3L1D4_HUMAN,tr|B0QYY7|B0QYY7_HUMAN,tr|A0A0G2JSB3|A0A0G2JSB3_HUMAN,tr|S4R3K7|S4R3K7_HUMAN" 25 1641.7299 1.21 20478 21571 2 1641.729061 821.8722 RNA binding protein fox-1 homolog 2 OS=Homo sapiens OX=9606 GN=RBFOX2 PE=1 SV=3 4.03 3629.5 - 1.22E+08 - - - -0.4928 - 3.105 0.667 - 619.1 1 2 0 -0.0008 15 0 0 0 1.46E+09 1.20E+09 - - - 6.7528 1 221125_WJC_METTL3_EV_vs_WT_F02.21573.21573.3 1.50E-06 13/56 K.GFGFVTFENSADADR[166.11].A "sp|O43251|RFOX2_HUMAN,sp|Q9NWB1|RFOX1_HUMAN,tr|A0A6Q8PGE0|A0A6Q8PGE0_HUMAN,tr|A0A6Q8PH77|A0A6Q8PH77_HUMAN,tr|A0A286YEU2|A0A286YEU2_HUMAN,tr|A0A087X2B1|A0A087X2B1_HUMAN,tr|F8VR27|F8VR27_HUMAN,tr|B7Z1U7|B7Z1U7_HUMAN,tr|B0QYV1|B0QYV1_HUMAN,tr|A0A6Q8PHA3|A0A6Q8PHA3_HUMAN,tr|F8VZY7|F8VZY7_HUMAN,tr|B0QYY4|B0QYY4_HUMAN,tr|J3KNW3|J3KNW3_HUMAN,tr|F8VZG9|F8VZG9_HUMAN,tr|F8VRS4|F8VRS4_HUMAN,tr|A0A6Q8PFM4|A0A6Q8PFM4_HUMAN,tr|S4R469|S4R469_HUMAN,tr|A0A804HKG7|A0A804HKG7_HUMAN,tr|A0A0G2JRD1|A0A0G2JRD1_HUMAN,tr|A0A0G2JRA5|A0A0G2JRA5_HUMAN,tr|A0A804HJM2|A0A804HJM2_HUMAN,tr|I3L1D4|I3L1D4_HUMAN,tr|B0QYY7|B0QYY7_HUMAN,tr|A0A0G2JSB3|A0A0G2JSB3_HUMAN,tr|S4R3K7|S4R3K7_HUMAN" 25 1641.7299 1.2 20479 21573 3 1641.729672 548.2506 RNA binding protein fox-1 homolog 2 OS=Homo sapiens OX=9606 GN=RBFOX2 PE=1 SV=3 4.03 3629.8 - 3.38E+06 - - - -0.1206 - 2.377 0.529 - 188.6 1 2 0 -0.0002 15 0 0 0 2.54E+07 2.11E+07 - - - 6.6971 0.9998 221125_WJC_METTL3_EV_vs_WT_F02.21574.21574.2 1.17E-05 13/22 R.DIISIAEDEDLR[166.11].V "sp|P12956|XRCC6_HUMAN,tr|B1AHC9|B1AHC9_HUMAN" 2 1397.6914 1.25 20480 21574 2 1397.688562 699.853 X-ray repair cross-complementing protein 6 OS=Homo sapiens OX=9606 GN=XRCC6 PE=1 SV=2 3.77 3629.8 - 3.04E+06 - - - -2.0019 - 2.602 0.482 - 626.1 1 2 0 -0.0028 12 0 0 0 9.32E+07 7.43E+07 - - - 5.1163 0.9998 221125_WJC_METTL3_EV_vs_WT_F02.21575.21575.2 0.00085 22-Nov R.DIISIAEDEDLR.V "sp|P12956|XRCC6_HUMAN,tr|B1AHC9|B1AHC9_HUMAN" 2 1387.6831 1.25 20481 21575 2 1387.684162 694.8488 X-ray repair cross-complementing protein 6 OS=Homo sapiens OX=9606 GN=XRCC6 PE=1 SV=2 3.77 3629.9 - 3.31E+06 - - - 0.7725 - 2.325 0.396 - 428.1 1 2 0 0.0011 12 0 0 0 9.32E+07 7.43E+07 - - - 4.1855 0.998 221125_WJC_METTL3_EV_vs_WT_F02.21578.21578.3 0.00424 Oct-56 K.TVDEAC[160.03]LLLAEYNGR.L "sp|Q9NQG5|RPR1B_HUMAN,tr|A2A2M0|A2A2M0_HUMAN,tr|A0A087X2D2|A0A087X2D2_HUMAN" 3 1722.8247 2.9 20484 21578 3 1722.817301 575.2822 Regulation of nuclear pre-mRNA domain-containing protein 1B OS=Homo sapiens OX=9606 GN=RPRD1B PE=1 SV=1 4.14 3630.1 - 1.60E+06 - - - -4.286 - 1.631 0.422 - 109 1 2 0 -0.0074 15 0 0 0 1.05E+07 3.61E+06 - - - 4.5193 1 221125_WJC_METTL3_EV_vs_WT_F02.21579.21579.2 9.66E-10 19/30 K.TGYAFVDC[160.03]PDESWALK.A "sp|O00425|IF2B3_HUMAN,tr|F8WD15|F8WD15_HUMAN" 2 1857.8244 1.46 20485 21579 2 1857.825478 929.9195 Insulin-like growth factor 2 mRNA-binding protein 3 OS=Homo sapiens OX=9606 GN=IGF2BP3 PE=1 SV=2 4.03 3630.3 - 1.38E+06 - - - 0.6066 - 3.32 0.692 - 1037.9 1 2 0 0.0011 16 0 0 0 2.11E+07 1.44E+07 - - - 7.1019 1 221125_WJC_METTL3_EV_vs_WT_F02.21580.21580.2 5.56E-12 16/30 K.TGYAFVDC[160.03]PDESWALK[136.11].A "sp|O00425|IF2B3_HUMAN,tr|F8WD15|F8WD15_HUMAN" 2 1865.8386 1.46 20486 21580 2 1865.837935 933.9266 Insulin-like growth factor 2 mRNA-binding protein 3 OS=Homo sapiens OX=9606 GN=IGF2BP3 PE=1 SV=2 4.03 3630.4 - 1.06E+06 - - - -0.3301 - 3.46 0.682 - 630 1 2 0 -0.0006 16 0 0 0 2.11E+07 1.44E+07 - - - 7.1298 0.9999 221125_WJC_METTL3_EV_vs_WT_F02.21582.21582.2 0.00105 26-Nov K.VLELDPALAPVVSR.E "sp|O00170|AIP_HUMAN,tr|A0A804HKK3|A0A804HKK3_HUMAN,tr|A0A804HKL7|A0A804HKL7_HUMAN,tr|A0A804HJ46|A0A804HJ46_HUMAN,tr|E9PMH2|E9PMH2_HUMAN,tr|A0A804HKH9|A0A804HKH9_HUMAN" 6 1477.8504 3.1 20488 21582 2 1477.849979 739.9325 AH receptor-interacting protein OS=Homo sapiens OX=9606 GN=AIP PE=1 SV=2 4.37 3630.6 - 835638 - - - -0.3052 - 2.535 0.458 - 286.4 1 2 0 -0.0004 14 0 0 0 5.01E+06 1.62E+06 - - - 4.7579 0.9996 221125_WJC_METTL3_EV_vs_WT_F02.21583.21583.2 1.14E-06 Nov-32 M.TLDVGPEDELPDWAAAK[136.11].E "sp|P15735|PHKG2_HUMAN,tr|H3BN16|H3BN16_HUMAN,tr|J3KNN3|J3KNN3_HUMAN,tr|H3BTW6|H3BTW6_HUMAN,tr|H3BP07|H3BP07_HUMAN" 5 1833.8876 1.05 20489 21583 2 1833.885296 917.9511 "Phosphorylase b kinase gamma catalytic chain, liver\testis isoform OS=Homo sapiens OX=9606 GN=PHKG2 PE=1 SV=1" 3.77 3630.8 - 640648 - - - -1.2618 - 2.231 0.341 - 264.8 1 2 0 -0.0023 17 0 0 0 5.88E+06 5.62E+06 - - - 3.5318 0.9982 221125_WJC_METTL3_EV_vs_WT_F02.21584.21584.2 3.45E-12 17/36 K.FVLSGANIMC[160.03]PGLTSPGAK[136.11].L "sp|Q9ULC4|MCTS1_HUMAN,tr|A0A3B3IRV3|A0A3B3IRV3_HUMAN" 2 1926.9787 0.32 20490 21584 2 1926.988486 964.4966 Malignant T-cell-amplified sequence 1 OS=Homo sapiens OX=9606 GN=MCTS1 PE=1 SV=1 8.22 3630.9 - 638362 - - - 5.0836 - 3.174 0.511 - 488 1 2 0 0.0098 19 0 0 0 1.78E+06 5.61E+06 - - - 5.6518 0.9998 221125_WJC_METTL3_EV_vs_WT_F02.21586.21586.2 2.44E-05 Nov-32 M.TLDVGPEDELPDWAAAK.E "sp|P15735|PHKG2_HUMAN,tr|H3BN16|H3BN16_HUMAN,tr|J3KNN3|J3KNN3_HUMAN,tr|H3BTW6|H3BTW6_HUMAN,tr|H3BP07|H3BP07_HUMAN" 5 1825.8734 0.99 20492 21586 2 1825.872087 913.944 "Phosphorylase b kinase gamma catalytic chain, liver\testis isoform OS=Homo sapiens OX=9606 GN=PHKG2 PE=1 SV=1" 3.77 3631.2 - 451997 - - - -0.7246 - 1.871 0.517 - 138.7 1 2 0 -0.0013 17 0 0 0 5.54E+06 5.62E+06 - - - 4.3994 0.9999 221125_WJC_METTL3_EV_vs_WT_F02.21591.21591.2 5.45E-06 13/22 K.LVAIVDVIDQNR[166.11].A "sp|P50914|RL14_HUMAN,tr|E7EPB3|E7EPB3_HUMAN" 2 1363.7699 1.03 20495 21591 2 1363.770006 682.8922 60S ribosomal protein L14 OS=Homo sapiens OX=9606 GN=RPL14 PE=1 SV=4 4.21 3631.8 - 3.01E+06 - - - 0.0887 - 2.733 0.54 - 783.4 1 2 0 0.0001 12 0 0 0 5.86E+07 5.68E+07 - - - 5.6748 0.9917 221125_WJC_METTL3_EV_vs_WT_F02.21592.21592.2 1.47E-05 18-Sep L.GSLNDLQFFR.Y "sp|P25311|ZA2G_HUMAN,tr|H7BZJ8|H7BZJ8_HUMAN,tr|C9JEV0|C9JEV0_HUMAN" 3 1195.5986 43.56 20496 21592 2 1195.597822 598.8066 Zinc-alpha-2-glycoprotein OS=Homo sapiens OX=9606 GN=AZGP1 PE=1 SV=2 5.84 3631.8 - 3.27E+06 - - - -0.6273 - 2.058 0.494 - 262.5 1 1 0 -0.0008 10 0 0 0 2.40E+07 5.51E+05 - - - 4.704 0.9998 221125_WJC_METTL3_EV_vs_WT_F02.21593.21593.2 0.000145 22-Oct R.FDQPLEASTWLK[136.11].N "sp|P51398|RT29_HUMAN,tr|V9GY11|V9GY11_HUMAN,tr|V9GYJ9|V9GYJ9_HUMAN,tr|V9GYJ3|V9GYJ3_HUMAN,tr|V9GZ03|V9GZ03_HUMAN,tr|V9GYL9|V9GYL9_HUMAN" 6 1441.7333 1.42 20497 21593 2 1441.734653 721.8739 "28S ribosomal protein S29, mitochondrial OS=Homo sapiens OX=9606 GN=DAP3 PE=1 SV=1" 4.37 3631.9 - 2.49E+06 - - - 0.9516 - 2.347 0.454 - 339 1 2 0 0.0014 12 0 0 0 2.43E+07 1.71E+07 - - - 4.6386 1 221125_WJC_METTL3_EV_vs_WT_F02.21594.21594.3 6.40E-06 17/52 R.TLFVSGLPLDIK[136.11]PR[166.11].E "sp|Q93062|RBPMS_HUMAN,tr|B4E3T4|B4E3T4_HUMAN" 2 1572.9358 1.83 20498 21594 3 1572.93472 525.3192 RNA-binding protein with multiple splicing OS=Homo sapiens OX=9606 GN=RBPMS PE=1 SV=1 8.41 3632 - 2.46E+06 - - - -0.7082 - 2.743 0.532 - 329.4 1 2 0 -0.0011 14 0 0 0 2.61E+07 1.42E+07 - - - 7.1526 0.9998 221125_WJC_METTL3_EV_vs_WT_F02.21595.21595.2 2.88E-07 17/28 K.SPFTVGVAAPLDLSK[136.11].L "sp|O75369|FLNB_HUMAN,tr|E7EN95|E7EN95_HUMAN,tr|A0A804HK76|A0A804HK76_HUMAN,tr|A0A804HL72|A0A804HL72_HUMAN" 4 1508.833 1 20499 21595 2 1508.836219 755.4238 Filamin-B OS=Homo sapiens OX=9606 GN=FLNB PE=1 SV=2 5.55 3632.1 - 1.57E+06 - - - 2.1368 - 3.236 0.505 - 812.6 1 2 0 0.0032 15 0 0 0 1.17E+07 1.17E+07 - - - 5.6571 1 221125_WJC_METTL3_EV_vs_WT_F02.21596.21596.2 3.51E-11 16/28 K.SPFTVGVAAPLDLSK.L "sp|O75369|FLNB_HUMAN,tr|E7EN95|E7EN95_HUMAN,tr|A0A804HK76|A0A804HK76_HUMAN,tr|A0A804HL72|A0A804HL72_HUMAN" 4 1500.8188 1.02 20500 21596 2 1500.817722 751.4167 Filamin-B OS=Homo sapiens OX=9606 GN=FLNB PE=1 SV=2 5.55 3632.2 - 1.52E+06 - - - -0.7149 - 2.944 0.583 - 689 1 2 0 -0.0011 15 0 0 0 1.22E+07 1.19E+07 - - - 6.0014 1 221125_WJC_METTL3_EV_vs_WT_F02.21598.21598.2 0.000265 18/34 R.IIPGGIYNADLNDEWVQR.A sp|P01037|CYTN_HUMAN 1 2072.0327 999 20502 21598 2 2072.032259 1037.0236 Cystatin-SN OS=Homo sapiens OX=9606 GN=CST1 PE=1 SV=3 4.03 3632.5 - 1.40E+06 - - - -0.2148 - 3.32 0.6 - 998.7 1 2 0 -0.0004 18 0 0 0 1.58E+07 0.00E+00 - - - 6.4226 0.9997 221125_WJC_METTL3_EV_vs_WT_F02.21600.21600.3 0.000872 13/72 K.LGISPLMLAAMNGHTAAVK[136.11].L "sp|O75179|ANR17_HUMAN,tr|H0YM23|H0YM23_HUMAN,tr|H0YLQ3|H0YLQ3_HUMAN" 3 1902.0311 1.71 20504 21600 3 1902.031137 635.0176 Ankyrin repeat domain-containing protein 17 OS=Homo sapiens OX=9606 GN=ANKRD17 PE=1 SV=3 8.76 3632.7 - 1.18E+06 - - - 0.0405 - 2.362 0.321 - 121.7 1 2 0 0.0001 19 0 0 0 1.01E+07 5.87E+06 - - - 4.2305 0.9999 221125_WJC_METTL3_EV_vs_WT_F02.21605.21605.3 1.03E-05 Dec-44 R.DIISIAEDEDLR[166.11].V "sp|P12956|XRCC6_HUMAN,tr|B1AHC9|B1AHC9_HUMAN" 2 1397.6914 1.32 20509 21605 3 1397.690861 466.9044 X-ray repair cross-complementing protein 6 OS=Homo sapiens OX=9606 GN=XRCC6 PE=1 SV=2 3.77 3633.2 - 918115 - - - -0.357 - 2.443 0.43 - 212.8 1 2 0 -0.0005 12 0 0 0 7.90E+06 5.98E+06 - - - 5.8098 0.9697 221125_WJC_METTL3_EV_vs_WT_F02.21606.21606.2 1.62E-06 13/34 E.YLQPLPSTPVSPIELDAK.K sp|Q96F45|ZN503_HUMAN 1 1967.0615 2.77 20510 21606 2 1967.068007 984.538 Zinc finger protein 503 OS=Homo sapiens OX=9606 GN=ZNF503 PE=1 SV=1 4.37 3633.4 - 679063 - - - 3.2851 - 2.634 0.54 - 395.8 1 1 0 0.0065 18 0 0 0 4.94E+06 1.78E+06 - - - 5.4085 1 221125_WJC_METTL3_EV_vs_WT_F02.21607.21607.3 0.00168 14/44 K.LVAIVDVIDQNR[166.11].A "sp|P50914|RL14_HUMAN,tr|E7EPB3|E7EPB3_HUMAN" 2 1363.7699 0.78 20511 21607 3 1363.769527 455.5972 60S ribosomal protein L14 OS=Homo sapiens OX=9606 GN=RPL14 PE=1 SV=4 4.21 3633.5 - 512542 - - - -0.2625 - 2.908 0.454 - 396.5 1 2 0 -0.0004 12 0 0 0 8.67E+06 1.11E+07 - - - 6.5604 0.9852 221125_WJC_METTL3_EV_vs_WT_F02.21608.21608.2 1.69E-05 30-Nov N.IWLEYGQYSVGGIGQK.G "sp|Q15020|SART3_HUMAN,tr|F8VVK9|F8VVK9_HUMAN,tr|A0A494C0L2|A0A494C0L2_HUMAN,tr|F8W667|F8W667_HUMAN,tr|A0A499FI31|A0A499FI31_HUMAN,tr|F8VZM2|F8VZM2_HUMAN" 6 1796.9097 -1 20512 21608 2 1796.913097 899.4621 Squamous cell carcinoma antigen recognized by T-cells 3 OS=Homo sapiens OX=9606 GN=SART3 PE=1 SV=1 6 3633.6 - 407209 - - - 1.871 - 2.312 0.517 - 274.6 1 1 0 0.0034 16 0 0 0 0.00E+00 0.00E+00 - - - 4.919 0.9999 221125_WJC_METTL3_EV_vs_WT_F02.21610.21610.2 2.66E-07 14/24 R.ASPLVAIGQTLAR.Q sp|Q9NSI2|SLX9_HUMAN 1 1295.7561 1.65 20513 21610 2 1295.756487 648.8853 Ribosome biogenesis protein SLX9 homolog OS=Homo sapiens OX=9606 GN=SLX9 PE=1 SV=2 9.79 3633.9 - 7.39E+06 - - - 0.2717 - 2.766 0.409 - 635.7 1 2 0 0.0004 13 0 0 0 2.35E+08 1.42E+08 - - - 4.673 0.9999 221125_WJC_METTL3_EV_vs_WT_F02.21613.21613.2 0.000104 18-Nov R.LGLDDFESLK.V "sp|Q9Y2H1|ST38L_HUMAN,tr|F5GY51|F5GY51_HUMAN,tr|I3L0D0|I3L0D0_HUMAN,tr|F5H7Z3|F5H7Z3_HUMAN" 4 1135.5761 2.53 20515 21613 2 1135.576911 568.7953 Serine\threonine-protein kinase 38-like OS=Homo sapiens OX=9606 GN=STK38L PE=1 SV=3 4.03 3634.1 - 3.14E+06 - - - 0.7098 - 2.261 0.545 - 271 1 2 0 0.0008 10 0 0 0 2.08E+07 8.22E+06 - - - 5.3433 0.9999 221125_WJC_METTL3_EV_vs_WT_F02.21614.21614.2 0.000135 13/22 K.IDSILEVVQTGR.T "sp|Q9NZW5|PALS2_HUMAN,tr|B8ZZG1|B8ZZG1_HUMAN" 2 1328.73 1.82 20516 21614 2 1328.730185 665.3723 Protein PALS2 OS=Homo sapiens OX=9606 GN=PALS2 PE=1 SV=2 4.37 3634.2 - 3.16E+06 - - - 0.1543 - 2.921 0.413 - 745.5 1 2 0 0.0002 12 0 0 0 2.14E+07 1.18E+07 - - - 4.9118 1 221125_WJC_METTL3_EV_vs_WT_F02.21615.21615.2 2.54E-09 16/30 R.LFVGNLPPDITEEEMR[166.11].K "sp|Q15233|NONO_HUMAN,tr|A0A7I2V535|A0A7I2V535_HUMAN,tr|A0A7I2V4N2|A0A7I2V4N2_HUMAN,tr|A0A7I2V4K9|A0A7I2V4K9_HUMAN,tr|A0A7I2V464|A0A7I2V464_HUMAN,tr|A0A7P0MRW0|A0A7P0MRW0_HUMAN,tr|C9IZL7|C9IZL7_HUMAN,tr|C9J4X2|C9J4X2_HUMAN,tr|A0A7I2YQK8|A0A7I2YQK8_HUMAN,tr|A0A7I2V4J2|A0A7I2V4J2_HUMAN,tr|A0A7I2V5Y7|A0A7I2V5Y7_HUMAN,tr|C9JYS8|C9JYS8_HUMAN" 12 1868.9218 0.9 20517 21615 2 1868.921385 935.4682 Non-POU domain-containing octamer-binding protein OS=Homo sapiens OX=9606 GN=NONO PE=1 SV=4 4 3634.3 - 2.49E+06 - - - -0.206 - 3.005 0.651 - 494.7 1 2 0 -0.0004 16 0 0 0 2.33E+07 2.59E+07 - - - 6.5542 1 221125_WJC_METTL3_EV_vs_WT_F02.21616.21616.3 0.000353 Nov-44 R.DIISIAEDEDLR.V "sp|P12956|XRCC6_HUMAN,tr|B1AHC9|B1AHC9_HUMAN" 2 1387.6831 1.32 20518 21616 3 1387.68344 463.5683 X-ray repair cross-complementing protein 6 OS=Homo sapiens OX=9606 GN=XRCC6 PE=1 SV=2 3.77 3634.4 - 2.03E+06 - - - 0.2522 - 2.542 0.462 - 158.3 1 2 0 0.0004 12 0 0 0 7.90E+06 5.98E+06 - - - 6.2767 0.9998 221125_WJC_METTL3_EV_vs_WT_F02.21618.21618.2 0.00139 22-Dec K.IDSILEVVQTGR[166.11].T "sp|Q9NZW5|PALS2_HUMAN,tr|B8ZZG1|B8ZZG1_HUMAN" 2 1338.7383 1.82 20520 21618 2 1338.739769 670.3764 Protein PALS2 OS=Homo sapiens OX=9606 GN=PALS2 PE=1 SV=2 4.37 3634.5 - 1.79E+06 - - - 1.1347 - 2.808 0.396 - 692.7 1 2 0 0.0015 12 0 0 0 2.14E+07 1.18E+07 - - - 4.682 0.9999 221125_WJC_METTL3_EV_vs_WT_F02.21619.21619.2 0.000423 16/26 R.IQQIETTLNILDAK.L "sp|Q9Y3C0|WASC3_HUMAN,tr|F5GXZ7|F5GXZ7_HUMAN,tr|H0YGN0|H0YGN0_HUMAN,tr|F5GWI9|F5GWI9_HUMAN,tr|F5GZ97|F5GZ97_HUMAN" 5 1598.8879 1.81 20521 21619 2 1598.890103 800.4512 WASH complex subunit 3 OS=Homo sapiens OX=9606 GN=WASHC3 PE=1 SV=1 4.37 3634.6 - 1.47E+06 - - - 1.3547 - 3.041 0.479 - 932.5 1 2 0 0.0022 14 0 0 0 8.48E+06 4.69E+06 - - - 5.3692 0.9991 221125_WJC_METTL3_EV_vs_WT_F02.21620.21620.2 0.00449 14/28 K.GYALVPIIVNSSTPK.S "sp|P82094|TMF1_HUMAN,tr|F8WF45|F8WF45_HUMAN,tr|A0A2R8Y7M0|A0A2R8Y7M0_HUMAN" 3 1557.8766 1.33 20522 21620 2 1557.882973 779.9456 TATA element modulatory factor OS=Homo sapiens OX=9606 GN=TMF1 PE=1 SV=2 8.59 3634.7 - 1.22E+06 - - - 4.0626 - 2.554 0.541 - 441.4 1 2 0 0.0063 15 0 0 0 3.77E+07 2.83E+07 - - - 5.3401 1 221125_WJC_METTL3_EV_vs_WT_F02.21621.21621.3 3.51E-06 14/52 R.DYAAYNVLDDPELR.Q sp|Q86SX6|GLRX5_HUMAN 1 1652.7682 2.66 20523 21621 3 1652.766238 551.93 "Glutaredoxin-related protein 5, mitochondrial OS=Homo sapiens OX=9606 GN=GLRX5 PE=1 SV=2" 3.84 3634.8 - 1.22E+06 - - - -1.1968 - 2.457 0.512 - 279.1 1 2 0 -0.002 14 0 0 0 9.32E+06 3.50E+06 - - - 6.6367 0.9994 221125_WJC_METTL3_EV_vs_WT_F02.21622.21622.3 0.000145 Nov-40 R.KVEDLFLTFAK.K "sp|Q13813|SPTN1_HUMAN,tr|A0A0D9SF54|A0A0D9SF54_HUMAN,tr|A0A0D9SGF6|A0A0D9SGF6_HUMAN" 3 1309.7282 1 20524 21622 3 1309.728304 437.5833 "Spectrin alpha chain, non-erythrocytic 1 OS=Homo sapiens OX=9606 GN=SPTAN1 PE=1 SV=3" 6.07 3634.9 - 1.20E+06 - - - 0.0878 - 2.115 0.267 - 137.2 1 2 0 0.0001 11 0 0 0 7.36E+06 7.33E+06 - - - 3.6447 1 221125_WJC_METTL3_EV_vs_WT_F02.21623.21623.3 0.00014 Dec-40 R.K[136.11]VEDLFLTFAK[136.11].K "sp|Q13813|SPTN1_HUMAN,tr|A0A0D9SF54|A0A0D9SF54_HUMAN,tr|A0A0D9SGF6|A0A0D9SGF6_HUMAN" 3 1325.7566 1 20525 21623 3 1325.75667 442.9261 "Spectrin alpha chain, non-erythrocytic 1 OS=Homo sapiens OX=9606 GN=SPTAN1 PE=1 SV=3" 6.07 3635 - 1.18E+06 - - - 0.0611 - 2.317 0.46 - 154.9 1 2 0 0.0001 11 0 0 0 7.36E+06 7.33E+06 - - - 6.0556 1 221125_WJC_METTL3_EV_vs_WT_F02.21624.21624.3 7.31E-05 14/52 K.VIAGLPDLTFMHAK.V "sp|Q6ULP2|AFTIN_HUMAN,tr|A0A0A0MSN6|A0A0A0MSN6_HUMAN,tr|B8ZZI9|B8ZZI9_HUMAN" 3 1511.817 1.65 20526 21624 3 1511.81638 504.9463 Aftiphilin OS=Homo sapiens OX=9606 GN=AFTPH PE=1 SV=3 6.71 3635.1 - 1.18E+06 - - - -0.424 - 2.413 0.484 - 222.6 1 2 0 -0.0006 14 0 0 0 1.35E+07 8.19E+06 - - - 6.2769 1 221125_WJC_METTL3_EV_vs_WT_F02.21625.21625.3 1.53E-08 17/60 R.LFVGNLPPDITEEEMR.K "sp|Q15233|NONO_HUMAN,tr|A0A7I2V535|A0A7I2V535_HUMAN,tr|A0A7I2V4N2|A0A7I2V4N2_HUMAN,tr|A0A7I2V4K9|A0A7I2V4K9_HUMAN,tr|A0A7I2V464|A0A7I2V464_HUMAN,tr|A0A7P0MRW0|A0A7P0MRW0_HUMAN,tr|C9IZL7|C9IZL7_HUMAN,tr|C9J4X2|C9J4X2_HUMAN,tr|A0A7I2YQK8|A0A7I2YQK8_HUMAN,tr|A0A7I2V4J2|A0A7I2V4J2_HUMAN,tr|A0A7I2V5Y7|A0A7I2V5Y7_HUMAN,tr|C9JYS8|C9JYS8_HUMAN" 12 1858.9135 0.71 20527 21625 3 1858.915822 620.6451 Non-POU domain-containing octamer-binding protein OS=Homo sapiens OX=9606 GN=NONO PE=1 SV=4 4 3635.2 - 1.15E+06 - - - 1.2491 - 3.439 0.58 - 521.2 1 2 0 0.0023 16 0 0 0 8.22E+06 1.15E+07 - - - 8.1751 0.9999 221125_WJC_METTL3_EV_vs_WT_F02.21626.21626.2 2.11E-05 14/26 R.IQQIETTLNILDAK[136.11].L "sp|Q9Y3C0|WASC3_HUMAN,tr|F5GXZ7|F5GXZ7_HUMAN,tr|H0YGN0|H0YGN0_HUMAN,tr|F5GWI9|F5GWI9_HUMAN,tr|F5GZ97|F5GZ97_HUMAN" 5 1606.9021 1.81 20528 21626 2 1606.903161 804.4583 WASH complex subunit 3 OS=Homo sapiens OX=9606 GN=WASHC3 PE=1 SV=1 4.37 3635.4 - 921552 - - - 0.6373 - 2.572 0.475 - 664.8 1 2 0 0.001 14 0 0 0 8.48E+06 4.69E+06 - - - 4.9197 0.9997 221125_WJC_METTL3_EV_vs_WT_F02.21630.21630.3 0.000203 17/44 K.VFREPLFLDLPK.S "sp|O60911|CATL2_HUMAN,tr|A0A7P0T983|A0A7P0T983_HUMAN,tr|A0A7P0Z415|A0A7P0Z415_HUMAN" 3 1472.8391 5.52 20532 21630 3 1472.839903 491.9537 Cathepsin L2 OS=Homo sapiens OX=9606 GN=CTSV PE=1 SV=2 6.04 3635.9 - 501370 - - - 0.5201 - 2.626 0.384 - 346 1 2 1 0.0008 12 0 0 0 4.52E+06 8.19E+05 - - - 5.4971 1 221125_WJC_METTL3_EV_vs_WT_F02.21633.21633.3 5.91E-08 14/48 R.ASPLVAIGQTLAR.Q sp|Q9NSI2|SLX9_HUMAN 1 1295.7561 1.76 20534 21633 3 1295.755389 432.926 Ribosome biogenesis protein SLX9 homolog OS=Homo sapiens OX=9606 GN=SLX9 PE=1 SV=2 9.79 3636.2 - 560675 - - - -0.5757 - 2.843 0.42 - 326.7 1 2 0 -0.0007 13 0 0 0 5.09E+07 2.89E+07 - - - 6.0553 0.9998 221125_WJC_METTL3_EV_vs_WT_F02.21634.21634.2 0.000288 22-Dec K.LVAIVDVIDQNR.A "sp|P50914|RL14_HUMAN,tr|E7EPB3|E7EPB3_HUMAN" 2 1353.7616 1.03 20535 21634 2 1353.763571 677.8881 60S ribosomal protein L14 OS=Homo sapiens OX=9606 GN=RPL14 PE=1 SV=4 4.21 3636.3 - 1.19E+07 - - - 1.4449 - 2.685 0.467 - 612.4 1 2 0 0.002 12 0 0 0 5.86E+07 5.68E+07 - - - 5.0884 0.9997 221125_WJC_METTL3_EV_vs_WT_F02.21636.21636.2 1.17E-08 22-Dec K.VDSLNDEINFLK.V sp|P19013|K2C4_HUMAN 1 1405.7089 18.21 20537 21636 2 1405.71238 703.8617 "Keratin, type II cytoskeletal 4 OS=Homo sapiens OX=9606 GN=KRT4 PE=1 SV=5" 4.03 3636.4 - 4.41E+06 - - - 2.4685 - 2.734 0.479 - 623.4 1 2 0 0.0035 12 0 0 0 1.95E+07 1.07E+06 - - - 5.2241 0.9995 221125_WJC_METTL3_EV_vs_WT_F02.21637.21637.2 0.00213 18-Dec K.LTLSALIDGK.N "sp|Q9Y277|VDAC3_HUMAN,sp|P21796|VDAC1_HUMAN" 2 1029.607 1.19 20538 21637 2 1029.609154 515.8108 Voltage-dependent anion-selective channel protein 3 OS=Homo sapiens OX=9606 GN=VDAC3 PE=1 SV=1 5.84 3636.4 - 4.20E+06 - - - 2.0814 - 2.324 0.355 - 384 1 2 0 0.0021 10 0 0 0 4.67E+07 3.91E+07 - - - 4.0162 0.9993 221125_WJC_METTL3_EV_vs_WT_F02.21638.21638.2 0.000101 20-Oct K.ISLEDIQAFEK.T sp|Q8WXX5|DNJC9_HUMAN 1 1291.666 1.38 20539 21638 2 1291.667891 646.8403 DnaJ homolog subfamily C member 9 OS=Homo sapiens OX=9606 GN=DNAJC9 PE=1 SV=1 4.14 3636.5 - 3.69E+06 - - - 1.4772 - 2.279 0.264 - 361.8 1 2 0 0.0019 11 0 0 0 1.54E+07 1.12E+07 - - - 3.2187 0.9994 221125_WJC_METTL3_EV_vs_WT_F02.21640.21640.2 4.06E-05 14/28 K.GYALVPIIVNSSTPK[136.11].S "sp|P82094|TMF1_HUMAN,tr|F8WF45|F8WF45_HUMAN,tr|A0A2R8Y7M0|A0A2R8Y7M0_HUMAN" 3 1565.8908 1.33 20541 21640 2 1565.89554 783.9527 TATA element modulatory factor OS=Homo sapiens OX=9606 GN=TMF1 PE=1 SV=2 8.59 3636.6 - 2.66E+06 - - - 2.9989 - 2.306 0.477 - 461 1 2 0 0.0047 15 0 0 0 3.77E+07 2.83E+07 - - - 4.6168 1 221125_WJC_METTL3_EV_vs_WT_F02.21641.21641.2 8.38E-06 15/24 K.GTQGVVTNFEIFR.M sp|P55884|EIF3B_HUMAN 1 1466.7518 1.1 20542 21641 2 1466.753902 734.3832 Eukaryotic translation initiation factor 3 subunit B OS=Homo sapiens OX=9606 GN=EIF3B PE=1 SV=3 6 3636.7 - 2.51E+06 - - - 1.4481 - 2.985 0.581 - 838.7 1 2 0 0.0021 13 0 0 0 2.80E+07 2.54E+07 - - - 6.1384 1 221125_WJC_METTL3_EV_vs_WT_F02.21642.21642.2 1.12E-09 17/30 R.LFVGNLPPDITEEEMR.K "sp|Q15233|NONO_HUMAN,tr|A0A7I2V535|A0A7I2V535_HUMAN,tr|A0A7I2V4N2|A0A7I2V4N2_HUMAN,tr|A0A7I2V4K9|A0A7I2V4K9_HUMAN,tr|A0A7I2V464|A0A7I2V464_HUMAN,tr|A0A7P0MRW0|A0A7P0MRW0_HUMAN,tr|C9IZL7|C9IZL7_HUMAN,tr|C9J4X2|C9J4X2_HUMAN,tr|A0A7I2YQK8|A0A7I2YQK8_HUMAN,tr|A0A7I2V4J2|A0A7I2V4J2_HUMAN,tr|A0A7I2V5Y7|A0A7I2V5Y7_HUMAN,tr|C9JYS8|C9JYS8_HUMAN" 12 1858.9135 0.9 20543 21642 2 1858.916501 930.464 Non-POU domain-containing octamer-binding protein OS=Homo sapiens OX=9606 GN=NONO PE=1 SV=4 4 3636.7 - 2.28E+06 - - - 1.6144 - 3.182 0.596 - 550.6 1 2 0 0.003 16 0 0 0 2.52E+07 2.81E+07 - - - 6.2879 1 221125_WJC_METTL3_EV_vs_WT_F02.21643.21643.3 3.11E-08 Dec-44 K.LVAIVDVIDQNR.A "sp|P50914|RL14_HUMAN,tr|E7EPB3|E7EPB3_HUMAN" 2 1353.7616 0.78 20544 21643 3 1353.762731 452.2611 60S ribosomal protein L14 OS=Homo sapiens OX=9606 GN=RPL14 PE=1 SV=4 4.21 3636.8 - 2.27E+06 - - - 0.8244 - 2.677 0.555 - 229.3 1 2 0 0.0011 12 0 0 0 8.67E+06 1.11E+07 - - - 7.4568 0.9981 221125_WJC_METTL3_EV_vs_WT_F02.21644.21644.2 0.0503 18-Sep R.DLGEELEALK.T "sp|P35749|MYH11_HUMAN,sp|P35579|MYH9_HUMAN" 2 1115.571 1.19 20545 21644 2 1115.57324 558.7928 Myosin-11 OS=Homo sapiens OX=9606 GN=MYH11 PE=1 SV=3 4 3636.9 - 2.07E+06 - - - 1.99 - 1.675 0.278 - 166.3 1 2 0 0.0022 10 0 0 0 9.77E+06 8.19E+06 - - - 2.5334 0.9996 221125_WJC_METTL3_EV_vs_WT_F02.21645.21645.2 0.0412 18-Oct R.DLGEELEALK[136.11].T "sp|P35749|MYH11_HUMAN,sp|P35579|MYH9_HUMAN" 2 1123.5852 1.19 20546 21645 2 1123.586003 562.7999 Myosin-11 OS=Homo sapiens OX=9606 GN=MYH11 PE=1 SV=3 4 3637 - 1.76E+06 - - - 0.6969 - 1.88 0.346 - 221.6 1 2 0 0.0008 10 0 0 0 9.77E+06 8.19E+06 - - - 3.3584 0.9997 221125_WJC_METTL3_EV_vs_WT_F02.21646.21646.2 0.000394 18-Dec R.LGLDDFESLK[136.11].V "sp|Q9Y2H1|ST38L_HUMAN,tr|F5GY51|F5GY51_HUMAN,tr|I3L0D0|I3L0D0_HUMAN,tr|F5H7Z3|F5H7Z3_HUMAN" 4 1143.5903 2.57 20547 21646 2 1143.592432 572.8024 Serine\threonine-protein kinase 38-like OS=Homo sapiens OX=9606 GN=STK38L PE=1 SV=3 4.03 3637.1 - 1.58E+06 - - - 1.8599 - 2.338 0.432 - 308.8 1 2 0 0.0021 10 0 0 0 2.11E+07 8.22E+06 - - - 4.6017 0.9999 221125_WJC_METTL3_EV_vs_WT_F02.21647.21647.3 1.19E-05 13/52 K.VIAGLPDLTFMHAK[136.11].V "sp|Q6ULP2|AFTIN_HUMAN,tr|A0A0A0MSN6|A0A0A0MSN6_HUMAN,tr|B8ZZI9|B8ZZI9_HUMAN" 3 1519.8312 1.64 20548 21647 3 1519.834142 507.6177 Aftiphilin OS=Homo sapiens OX=9606 GN=AFTPH PE=1 SV=3 6.71 3637.2 - 1.50E+06 - - - 1.9219 - 2.284 0.477 - 186.1 1 2 0 0.0029 14 0 0 0 1.37E+07 8.35E+06 - - - 6.0522 0.9996 221125_WJC_METTL3_EV_vs_WT_F02.21648.21648.2 2.48E-06 18-Oct K.DYTEGWVEFR[166.11].D sp|Q9ULW3|ABT1_HUMAN 1 1310.5807 0.56 20549 21648 2 1310.584284 656.2976 Activator of basal transcription 1 OS=Homo sapiens OX=9606 GN=ABT1 PE=1 SV=1 4.14 3637.3 - 1.41E+06 - - - 2.7446 - 1.923 0.562 - 402.4 1 2 0 0.0036 10 0 0 0 5.63E+06 9.99E+06 - - - 5.016 0.9815 221125_WJC_METTL3_EV_vs_WT_F02.21649.21649.2 0.00182 26-Dec K.FIQPNIGELPTALK.G sp|Q14008|CKAP5_HUMAN 1 1539.8661 0.77 20550 21649 2 1539.877193 770.9403 Cytoskeleton-associated protein 5 OS=Homo sapiens OX=9606 GN=CKAP5 PE=1 SV=3 6 3637.4 - 1.33E+06 - - - 7.2169 - 1.953 0.422 - 393.4 1 2 0 0.0111 14 0 0 0 1.07E+07 1.40E+07 - - - 3.8341 0.9998 221125_WJC_METTL3_EV_vs_WT_F02.21650.21650.2 3.73E-06 26-Dec K.FIQPNIGELPTALK[136.11].G sp|Q14008|CKAP5_HUMAN 1 1547.8803 0.77 20551 21650 2 1547.882462 774.9474 Cytoskeleton-associated protein 5 OS=Homo sapiens OX=9606 GN=CKAP5 PE=1 SV=3 6 3637.5 - 1.29E+06 - - - 1.4097 - 2.159 0.568 - 393.7 1 2 0 0.0022 14 0 0 0 1.07E+07 1.40E+07 - - - 5.1669 1 221125_WJC_METTL3_EV_vs_WT_F02.21651.21651.2 6.38E-13 17/30 R.GYSYDLEVEQAYDLAR[166.11].R sp|P28074|PSB5_HUMAN 1 1900.8718 0.75 20552 21651 2 1900.873153 951.4432 Proteasome subunit beta type-5 OS=Homo sapiens OX=9606 GN=PSMB5 PE=1 SV=3 3.92 3637.7 - 1.28E+06 - - - 0.6892 - 3.46 0.71 - 1173.7 1 2 0 0.0013 16 0 0 0 4.20E+06 5.62E+06 - - - 7.3364 0.9998 221125_WJC_METTL3_EV_vs_WT_F02.21654.21654.2 0.000511 24-Nov K.AGYPQYVSEILEK[136.11].V "sp|P42704|LPPRC_HUMAN,tr|A0A804HI14|A0A804HI14_HUMAN,tr|A0A804HL40|A0A804HL40_HUMAN,tr|A0A804HKJ0|A0A804HKJ0_HUMAN,tr|A0A804HKR3|A0A804HKR3_HUMAN,tr|A0A0C4DG06|A0A0C4DG06_HUMAN,tr|A0A804HIN4|A0A804HIN4_HUMAN,tr|A0A804HLG8|A0A804HLG8_HUMAN,tr|A0A804HIV5|A0A804HIV5_HUMAN,tr|A0A804HHY9|A0A804HHY9_HUMAN,tr|A0A804HJH8|A0A804HJH8_HUMAN,tr|B8ZZ38|B8ZZ38_HUMAN,tr|A0A804HI40|A0A804HI40_HUMAN,tr|A0A804HJZ1|A0A804HJZ1_HUMAN,tr|C9JCA9|C9JCA9_HUMAN,tr|A0A804HIQ7|A0A804HIQ7_HUMAN,tr|A0A804HK30|A0A804HK30_HUMAN,tr|A0A804HKI2|A0A804HKI2_HUMAN,tr|A0A804HKR5|A0A804HKR5_HUMAN,tr|A0A804HKX0|A0A804HKX0_HUMAN,tr|A0A804HIG4|A0A804HIG4_HUMAN,tr|A0A804HK02|A0A804HK02_HUMAN" 22 1503.7701 0.13 20554 21654 2 1503.770496 752.8923 "Leucine-rich PPR motif-containing protein, mitochondrial OS=Homo sapiens OX=9606 GN=LRPPRC PE=1 SV=3" 4.53 3638 - 899785 - - - 0.2893 - 1.849 0.457 - 226.6 1 2 0 0.0004 13 0 0 0 1.45E+06 1.16E+07 - - - 3.9938 0.9996 221125_WJC_METTL3_EV_vs_WT_F02.21655.21655.2 0.000508 18-Nov K.LTLSALIDGK[136.11].N "sp|Q9Y277|VDAC3_HUMAN,sp|P21796|VDAC1_HUMAN" 2 1037.6212 1.19 20555 21655 2 1037.623611 519.8179 Voltage-dependent anion-selective channel protein 3 OS=Homo sapiens OX=9606 GN=VDAC3 PE=1 SV=1 5.84 3638 - 9.30E+06 - - - 2.313 - 2.256 0.456 - 328.4 1 2 0 0.0024 10 0 0 0 4.67E+07 3.91E+07 - - - 4.6792 1 221125_WJC_METTL3_EV_vs_WT_F02.21656.21656.3 2.76E-13 24/64 R.EGEELVMDEEAYVLYHR[166.11].A sp|Q9BQ67|GRWD1_HUMAN 1 2090.9494 1.31 20556 21656 3 2090.956324 697.9904 Glutamate-rich WD repeat-containing protein 1 OS=Homo sapiens OX=9606 GN=GRWD1 PE=1 SV=1 4.14 3638.1 - 2.17E+06 - - - 3.2913 - 3.773 0.69 - 1078.8 1 2 0 0.0069 17 0 0 0 1.24E+07 9.47E+06 - - - 9.5855 1 221125_WJC_METTL3_EV_vs_WT_F02.21657.21657.3 6.15E-13 20/68 K.LDEIYVAGLVAHSDLDER.A "sp|O60506|HNRPQ_HUMAN,tr|A0A7I2YQV8|A0A7I2YQV8_HUMAN,tr|A0A7I2YQN2|A0A7I2YQN2_HUMAN,tr|A0A7I2V5Q6|A0A7I2V5Q6_HUMAN,tr|A0A7I2V4Z0|A0A7I2V4Z0_HUMAN,tr|A0A7I2V4J0|A0A7I2V4J0_HUMAN,tr|F6UXX1|F6UXX1_HUMAN,tr|A0A7I2V346|A0A7I2V346_HUMAN" 8 2014.0007 1.23 20557 21657 3 2014.006104 672.3409 Heterogeneous nuclear ribonucleoprotein Q OS=Homo sapiens OX=9606 GN=SYNCRIP PE=1 SV=2 4.1 3638.2 - 2.13E+06 - - - 2.6658 - 4.243 0.676 - 543.5 1 2 0 0.0054 18 0 0 0 2.49E+07 2.03E+07 - - - 9.6741 1 221125_WJC_METTL3_EV_vs_WT_F02.21658.21658.2 9.19E-09 14/22 K.TVEDYFC[160.03]FC[160.03]YGK.A "sp|P78347|GTF2I_HUMAN,tr|A0A494C1K3|A0A494C1K3_HUMAN" 2 1587.6374 1.38 20558 21658 2 1587.640794 794.826 General transcription factor II-I OS=Homo sapiens OX=9606 GN=GTF2I PE=1 SV=2 4.37 3638.3 - 1.79E+06 - - - 2.1365 - 2.476 0.663 - 467.6 1 2 0 0.0034 12 0 0 0 1.94E+07 1.41E+07 - - - 6.3224 0.9997 221125_WJC_METTL3_EV_vs_WT_F02.21659.21659.2 0.000789 24-Oct K.IIQDIETIESNWR.C "sp|Q9Y297|FBW1A_HUMAN,sp|Q9UKB1|FBW1B_HUMAN,tr|E5RGC1|E5RGC1_HUMAN,tr|B7Z3H4|B7Z3H4_HUMAN" 4 1615.8206 3.57 20559 21659 2 1615.821295 808.9176 F-box\WD repeat-containing protein 1A OS=Homo sapiens OX=9606 GN=BTRC PE=1 SV=1 4.14 3638.4 - 1.77E+06 - - - 0.4388 - 2.151 0.373 - 242.4 1 2 0 0.0007 13 0 0 0 1.88E+07 5.26E+06 - - - 3.7615 1 221125_WJC_METTL3_EV_vs_WT_F02.21660.21660.2 4.79E-08 22-Sep K.TVEDYFC[160.03]FC[160.03]YGK[136.11].A "sp|P78347|GTF2I_HUMAN,tr|A0A494C1K3|A0A494C1K3_HUMAN" 2 1595.6516 1.38 20560 21660 2 1595.654795 798.8331 General transcription factor II-I OS=Homo sapiens OX=9606 GN=GTF2I PE=1 SV=2 4.37 3638.4 - 1.48E+06 - - - 2.0011 - 1.915 0.696 - 154.2 1 2 0 0.0032 12 0 0 0 1.94E+07 1.41E+07 - - - 5.8902 1 221125_WJC_METTL3_EV_vs_WT_F02.21661.21661.3 1.02E-06 16/56 K.GYALVPIIVNSSTPK[136.11].S "sp|P82094|TMF1_HUMAN,tr|F8WF45|F8WF45_HUMAN,tr|A0A2R8Y7M0|A0A2R8Y7M0_HUMAN" 3 1565.8908 1.91 20561 21661 3 1565.894918 522.9709 TATA element modulatory factor OS=Homo sapiens OX=9606 GN=TMF1 PE=1 SV=2 8.59 3638.5 - 1.44E+06 - - - 2.6017 - 3.195 0.525 - 373.2 1 2 0 0.0041 15 0 0 0 3.01E+07 1.57E+07 - - - 7.4231 0.9993 221125_WJC_METTL3_EV_vs_WT_F02.21662.21662.3 0.000675 Sep-48 K.IIQDIETIESNWR.C "sp|Q9Y297|FBW1A_HUMAN,sp|Q9UKB1|FBW1B_HUMAN,tr|E5RGC1|E5RGC1_HUMAN,tr|B7Z3H4|B7Z3H4_HUMAN" 4 1615.8206 1.48 20562 21662 3 1615.823284 539.6141 F-box\WD repeat-containing protein 1A OS=Homo sapiens OX=9606 GN=BTRC PE=1 SV=1 4.14 3638.6 - 1.32E+06 - - - 1.6697 - 1.911 0.328 - 105.4 1 2 0 0.0027 13 0 0 0 5.00E+06 3.37E+06 - - - 3.952 0.9983 221125_WJC_METTL3_EV_vs_WT_F02.21663.21663.2 4.35E-05 24-Dec K.NPEQVDLYQFMAK.D sp|P56192|SYMC_HUMAN 1 1581.7497 1 20563 21663 2 1581.757277 791.8821 "Methionine--tRNA ligase, cytoplasmic OS=Homo sapiens OX=9606 GN=MARS1 PE=1 SV=2" 4.37 3638.7 - 1.12E+06 - - - 4.7719 - 2.605 0.494 - 403.1 1 2 0 0.0075 13 0 0 0 4.93E+06 4.93E+06 - - - 5.1446 1 221125_WJC_METTL3_EV_vs_WT_F02.21664.21664.2 1.44E-08 16/30 K.FYPLEIDYGQDEEAVK.K sp|P09874|PARP1_HUMAN 1 1914.8887 0.8 20564 21664 2 1914.891329 958.4516 Poly [ADP-ribose] polymerase 1 OS=Homo sapiens OX=9606 GN=PARP1 PE=1 SV=4 3.83 3638.8 - 1.09E+06 - - - 1.3599 - 2.764 0.638 - 670.4 1 2 0 0.0026 16 0 0 0 6.10E+06 7.61E+06 - - - 6.252 0.9998 221125_WJC_METTL3_EV_vs_WT_F02.21665.21665.3 0.00131 Nov-60 R.GYSYDLEVEQAYDLAR[166.11].R sp|P28074|PSB5_HUMAN 1 1900.8718 -1 20565 21665 3 1900.877118 634.6312 Proteasome subunit beta type-5 OS=Homo sapiens OX=9606 GN=PSMB5 PE=1 SV=3 3.92 3638.9 - 1.03E+06 - - - 2.775 - 2.214 0.441 - 149.4 1 2 0 0.0053 16 0 0 0 0.00E+00 0.00E+00 - - - 5.4946 1 221125_WJC_METTL3_EV_vs_WT_F02.21666.21666.3 1.62E-10 19/64 R.EAIDSPVSFLALHNQIR.N sp|Q92900|RENT1_HUMAN 1 1909.0058 1.99 20566 21666 3 1909.010333 637.3425 Regulator of nonsense transcripts 1 OS=Homo sapiens OX=9606 GN=UPF1 PE=1 SV=2 5.32 3639 - 969898 - - - 2.395 - 3.485 0.594 - 593.6 1 2 0 0.0046 17 0 0 0 7.41E+06 3.72E+06 - - - 8.3153 1 221125_WJC_METTL3_EV_vs_WT_F02.21667.21667.2 6.62E-14 15/30 R.GYSYDLEVEQAYDLAR.R sp|P28074|PSB5_HUMAN 1 1890.8636 0.75 20567 21667 2 1890.866956 946.4391 Proteasome subunit beta type-5 OS=Homo sapiens OX=9606 GN=PSMB5 PE=1 SV=3 3.92 3639.1 - 943896 - - - 1.7891 - 3.277 0.674 - 856.8 1 2 0 0.0034 16 0 0 0 4.20E+06 5.62E+06 - - - 6.9362 0.9998 221125_WJC_METTL3_EV_vs_WT_F02.21668.21668.2 4.02E-08 26-Nov K.AGFFGTVVEYGAER[166.11].K sp|Q9NVH1|DJC11_HUMAN 1 1511.7284 -1 20568 21668 2 1511.731843 756.8715 DnaJ homolog subfamily C member 11 OS=Homo sapiens OX=9606 GN=DNAJC11 PE=1 SV=2 4.53 3639.2 - 926284 - - - 2.2683 - 2.528 0.584 - 249 1 2 0 0.0034 14 0 0 0 0.00E+00 0.00E+00 - - - 5.6807 1 221125_WJC_METTL3_EV_vs_WT_F02.21669.21669.2 2.98E-13 18/30 K.FYPLEIDYGQDEEAVK[136.11].K sp|P09874|PARP1_HUMAN 1 1922.9029 0.8 20569 21669 2 1922.905257 962.4587 Poly [ADP-ribose] polymerase 1 OS=Homo sapiens OX=9606 GN=PARP1 PE=1 SV=4 3.83 3639.4 - 925478 - - - 1.2127 - 2.932 0.73 - 862.5 1 2 0 0.0023 16 0 0 0 6.10E+06 7.61E+06 - - - 7.0767 1 221125_WJC_METTL3_EV_vs_WT_F02.21670.21670.2 1.33E-07 16/28 R.NYLEGIYNVPVAAVR.T "sp|Q16540|RM23_HUMAN,tr|H7C2P7|H7C2P7_HUMAN,tr|A8MYK1|A8MYK1_HUMAN,tr|A8MVT4|A8MVT4_HUMAN,tr|A6NJD9|A6NJD9_HUMAN" 5 1676.8886 1.95 20570 21670 2 1676.89322 839.4516 "39S ribosomal protein L23, mitochondrial OS=Homo sapiens OX=9606 GN=MRPL23 PE=1 SV=1" 6 3639.5 - 842428 - - - 2.7515 - 2.924 0.625 - 884.4 1 2 0 0.0046 15 0 0 0 2.00E+07 1.03E+07 - - - 6.2937 1 221125_WJC_METTL3_EV_vs_WT_F02.21671.21671.2 1.51E-06 17/32 R.AAVEEGIVLGGGC[160.03]ALLR[166.11].C "sp|P10809|CH60_HUMAN,tr|A0A7I2V2X6|A0A7I2V2X6_HUMAN,tr|A0A7I2YQK6|A0A7I2YQK6_HUMAN,tr|A0A7I2V599|A0A7I2V599_HUMAN" 4 1693.9061 2.04 20571 21671 2 1693.910339 847.9603 "60 kDa heat shock protein, mitochondrial OS=Homo sapiens OX=9606 GN=HSPD1 PE=1 SV=2" 4.53 3639.6 - 807277 - - - 2.5255 - 3.438 0.542 - 711.3 1 2 0 0.0043 17 0 0 0 3.94E+07 1.93E+07 - - - 6.0789 0.9978 221125_WJC_METTL3_EV_vs_WT_F02.21672.21672.2 0.00558 13/24 K.AGYPQYVSEILEK.V "sp|P42704|LPPRC_HUMAN,tr|A0A804HI14|A0A804HI14_HUMAN,tr|A0A804HL40|A0A804HL40_HUMAN,tr|A0A804HKJ0|A0A804HKJ0_HUMAN,tr|A0A804HKR3|A0A804HKR3_HUMAN,tr|A0A0C4DG06|A0A0C4DG06_HUMAN,tr|A0A804HIN4|A0A804HIN4_HUMAN,tr|A0A804HLG8|A0A804HLG8_HUMAN,tr|A0A804HIV5|A0A804HIV5_HUMAN,tr|A0A804HHY9|A0A804HHY9_HUMAN,tr|A0A804HJH8|A0A804HJH8_HUMAN,tr|B8ZZ38|B8ZZ38_HUMAN,tr|A0A804HI40|A0A804HI40_HUMAN,tr|A0A804HJZ1|A0A804HJZ1_HUMAN,tr|C9JCA9|C9JCA9_HUMAN,tr|A0A804HIQ7|A0A804HIQ7_HUMAN,tr|A0A804HK30|A0A804HK30_HUMAN,tr|A0A804HKI2|A0A804HKI2_HUMAN,tr|A0A804HKR5|A0A804HKR5_HUMAN,tr|A0A804HKX0|A0A804HKX0_HUMAN,tr|A0A804HIG4|A0A804HIG4_HUMAN,tr|A0A804HK02|A0A804HK02_HUMAN" 22 1495.7559 0.26 20572 21672 2 1495.763023 748.8852 "Leucine-rich PPR motif-containing protein, mitochondrial OS=Homo sapiens OX=9606 GN=LRPPRC PE=1 SV=3" 4.53 3639.8 - 737020 - - - 4.7882 - 2.475 0.458 - 442.5 1 2 0 0.0072 13 0 0 0 4.30E+06 1.68E+07 - - - 4.7474 1 221125_WJC_METTL3_EV_vs_WT_F02.21674.21674.2 1.14E-09 19/32 K.GYGC[160.03]AGVSSVAYGLLAR[166.11].E "sp|Q92947|GCDH_HUMAN,tr|K7EKT3|K7EKT3_HUMAN,tr|K7EKH1|K7EKH1_HUMAN" 3 1709.8435 1.2 20573 21674 2 1709.846311 855.929 "Glutaryl-CoA dehydrogenase, mitochondrial OS=Homo sapiens OX=9606 GN=GCDH PE=1 SV=1" 8.2 3640 - 1.92E+06 - - - 1.6668 - 3.683 0.714 - 990.7 1 2 0 0.0029 17 0 0 0 1.29E+07 1.07E+07 - - - 7.519 0.9998 221125_WJC_METTL3_EV_vs_WT_F02.21676.21676.2 3.25E-05 20-Dec R.FC[160.03]LGLLSNVNR[166.11].N "sp|Q99717|SMAD5_HUMAN,sp|O15198|SMAD9_HUMAN,sp|Q15796|SMAD2_HUMAN,sp|P84022|SMAD3_HUMAN,sp|Q15797|SMAD1_HUMAN,tr|H3BVD1|H3BVD1_HUMAN,tr|H0YAK7|H0YAK7_HUMAN,tr|H0YNV1|H0YNV1_HUMAN,tr|H0YKE2|H0YKE2_HUMAN,tr|B7Z5N5|B7Z5N5_HUMAN" 10 1301.679 1.46 20575 21676 2 1301.680877 651.8468 Mothers against decapentaplegic homolog 5 OS=Homo sapiens OX=9606 GN=SMAD5 PE=1 SV=1 8.25 3640.2 - 4.53E+06 - - - 1.4719 - 2.191 0.465 - 591.1 1 2 0 0.0019 11 0 0 0 3.39E+07 2.32E+07 - - - 4.5968 1 221125_WJC_METTL3_EV_vs_WT_F02.21677.21677.3 2.11E-08 23/68 K.LDEIYVAGLVAHSDLDER[166.11].A "sp|O60506|HNRPQ_HUMAN,tr|A0A7I2YQV8|A0A7I2YQV8_HUMAN,tr|A0A7I2YQN2|A0A7I2YQN2_HUMAN,tr|A0A7I2V5Q6|A0A7I2V5Q6_HUMAN,tr|A0A7I2V4Z0|A0A7I2V4Z0_HUMAN,tr|A0A7I2V4J0|A0A7I2V4J0_HUMAN,tr|F6UXX1|F6UXX1_HUMAN,tr|A0A7I2V346|A0A7I2V346_HUMAN" 8 2024.009 1.16 20576 21677 3 2024.013433 675.6769 Heterogeneous nuclear ribonucleoprotein Q OS=Homo sapiens OX=9606 GN=SYNCRIP PE=1 SV=2 4.1 3640.2 - 4.19E+06 - - - 2.1877 - 4.464 0.657 - 817.9 1 2 0 0.0044 18 0 0 0 2.80E+07 2.42E+07 - - - 9.589 1 221125_WJC_METTL3_EV_vs_WT_F02.21678.21678.3 4.69E-11 19/64 R.EGEELVMDEEAYVLYHR.A sp|Q9BQ67|GRWD1_HUMAN 1 2080.9412 1.31 20577 21678 3 2080.948859 694.6543 Glutamate-rich WD repeat-containing protein 1 OS=Homo sapiens OX=9606 GN=GRWD1 PE=1 SV=1 4.14 3640.3 - 3.44E+06 - - - 3.694 - 3.499 0.676 - 760 1 2 0 0.0077 17 0 0 0 1.24E+07 9.47E+06 - - - 9.2387 0.9994 221125_WJC_METTL3_EV_vs_WT_F02.21679.21679.2 0.000211 20-Sep K.VSEQGLIEILK[136.11].K "sp|O14737|PDCD5_HUMAN,tr|K7EQA1|K7EQA1_HUMAN" 2 1235.7217 0.9 20578 21679 2 1235.724674 618.8681 Programmed cell death protein 5 OS=Homo sapiens OX=9606 GN=PDCD5 PE=1 SV=3 4.53 3640.3 - 2.33E+06 - - - 2.4439 - 2.128 0.428 - 264.2 1 2 0 0.003 11 0 0 0 7.30E+06 8.11E+06 - - - 4.2442 1 221125_WJC_METTL3_EV_vs_WT_F02.21680.21680.2 2.47E-09 16/28 R.NYLEGIYNVPVAAVR[166.11].T "sp|Q16540|RM23_HUMAN,tr|H7C2P7|H7C2P7_HUMAN,tr|A8MYK1|A8MYK1_HUMAN,tr|A8MVT4|A8MVT4_HUMAN,tr|A6NJD9|A6NJD9_HUMAN" 5 1686.8969 1.85 20579 21680 2 1686.899381 844.4557 "39S ribosomal protein L23, mitochondrial OS=Homo sapiens OX=9606 GN=MRPL23 PE=1 SV=1" 6 3640.4 - 2.14E+06 - - - 1.485 - 2.883 0.621 - 933.9 1 2 0 0.0025 15 0 0 0 1.90E+07 1.03E+07 - - - 6.2301 0.9999 221125_WJC_METTL3_EV_vs_WT_F02.21685.21685.3 2.46E-06 Dec-64 K.GYGC[160.03]AGVSSVAYGLLAR[166.11].E "sp|Q92947|GCDH_HUMAN,tr|K7EKT3|K7EKT3_HUMAN,tr|K7EKH1|K7EKH1_HUMAN" 3 1709.8435 1.33 20584 21685 3 1709.84824 570.9551 "Glutaryl-CoA dehydrogenase, mitochondrial OS=Homo sapiens OX=9606 GN=GCDH PE=1 SV=1" 8.2 3640.9 - 979583 - - - 2.795 - 2.199 0.497 - 154.8 1 2 0 0.0048 17 0 0 0 4.74E+06 3.56E+06 - - - 6.0705 0.9997 221125_WJC_METTL3_EV_vs_WT_F02.21686.21686.2 0.000873 26-Nov R.LMSINYLGSVYPSR.A "sp|Q06136|KDSR_HUMAN,tr|K7EQS7|K7EQS7_HUMAN,tr|K7ERC8|K7ERC8_HUMAN" 3 1598.8127 3.12 20585 21686 2 1598.812103 800.4136 3-ketodihydrosphingosine reductase OS=Homo sapiens OX=9606 GN=KDSR PE=1 SV=1 8.59 3640.9 - 1.57E+06 - - - -0.3509 - 1.719 0.445 - 122.3 1 2 0 -0.0006 14 0 0 0 4.73E+06 1.52E+06 - - - 3.6871 1 221125_WJC_METTL3_EV_vs_WT_F02.21688.21688.3 0.00198 18/56 R.LFPLIQAMHPTLAGK.L "sp|Q9H361|PABP3_HUMAN,sp|P11940|PABP1_HUMAN,tr|H0YAS6|H0YAS6_HUMAN,tr|H0YB75|H0YB75_HUMAN,tr|A0A7I2YQE4|A0A7I2YQE4_HUMAN,tr|A0A7I2V649|A0A7I2V649_HUMAN,tr|H0YAR2|H0YAR2_HUMAN,tr|E7ERJ7|E7ERJ7_HUMAN,tr|A0A7I2YQ88|A0A7I2YQ88_HUMAN,tr|A0A087WTT1|A0A087WTT1_HUMAN,tr|A0A7I2YQ90|A0A7I2YQ90_HUMAN,tr|A0A7I2V4N4|A0A7I2V4N4_HUMAN,tr|E7EQV3|E7EQV3_HUMAN" 13 1635.9171 1.27 20587 21688 3 1635.918759 546.313 Polyadenylate-binding protein 3 OS=Homo sapiens OX=9606 GN=PABPC3 PE=1 SV=2 8.76 3641.1 - 878979 - - - 1.0331 - 2.879 0.433 - 277.6 1 2 0 0.0017 15 0 0 0 4.66E+08 3.67E+08 - - - 6.1263 0.995 221125_WJC_METTL3_EV_vs_WT_F02.21689.21689.3 4.53E-07 15/60 R.APVPASELLASGVLSR[166.11].A "sp|Q15149|PLEC_HUMAN,tr|H0YDN1|H0YDN1_HUMAN" 2 1575.886 1.95 20588 21689 3 1575.876265 526.3026 Plectin OS=Homo sapiens OX=9606 GN=PLEC PE=1 SV=3 6.05 3641.2 - 736537 - - - -6.1629 - 3.118 0.308 - 306.1 1 2 0 -0.0097 16 0 0 0 1.42E+07 7.26E+06 - - - 4.8891 0.9891 221125_WJC_METTL3_EV_vs_WT_F02.21691.21691.3 0.0134 Aug-36 R.SRGFGFILFK.D "sp|Q99729|ROAA_HUMAN,tr|D6R9P3|D6R9P3_HUMAN,tr|D6RD18|D6RD18_HUMAN,tr|D6RBZ0|D6RBZ0_HUMAN" 4 1170.655 -1 20590 21691 3 1170.656505 391.2256 Heterogeneous nuclear ribonucleoprotein A\B OS=Homo sapiens OX=9606 GN=HNRNPAB PE=1 SV=2 11 3641.5 - 571815 - - - 1.3155 - 1.515 0.281 - 87.4 1 2 1 0.0015 10 0 0 0 0.00E+00 0.00E+00 - - - 2.8856 1 221125_WJC_METTL3_EV_vs_WT_F02.21692.21692.2 5.45E-06 17/32 R.EATGVLLSIDGEDGIVR[166.11].M sp|O00267|SPT5H_HUMAN 1 1752.9133 1.03 20591 21692 2 1752.916955 877.4639 Transcription elongation factor SPT5 OS=Homo sapiens OX=9606 GN=SUPT5H PE=1 SV=1 3.92 3641.6 - 552365 - - - 2.0771 - 3.347 0.522 - 926 1 2 0 0.0036 17 0 0 0 8.14E+06 7.89E+06 - - - 5.8654 1 221125_WJC_METTL3_EV_vs_WT_F02.21695.21695.2 1.70E-08 15/32 R.EATGVLLSIDGEDGIVR.M sp|O00267|SPT5H_HUMAN 1 1742.905 1.03 20593 21695 2 1742.921117 872.4598 Transcription elongation factor SPT5 OS=Homo sapiens OX=9606 GN=SUPT5H PE=1 SV=1 3.92 3642.1 - 989219 - - - 9.222 - 3.05 0.549 - 720.3 1 2 0 0.0161 17 0 0 0 8.14E+06 7.89E+06 - - - 5.8325 0.9997 221125_WJC_METTL3_EV_vs_WT_F02.21698.21698.2 0.000782 13/20 K.QVQIDGLVVLK.L "sp|O15372|EIF3H_HUMAN,tr|B3KS98|B3KS98_HUMAN,tr|E5RFW7|E5RFW7_HUMAN,tr|E5RFH0|E5RFH0_HUMAN" 4 1210.7285 1.83 20596 21698 2 1210.731038 606.3715 Eukaryotic translation initiation factor 3 subunit H OS=Homo sapiens OX=9606 GN=EIF3H PE=1 SV=1 5.84 3642.3 - 5.57E+06 - - - 2.0764 - 2.354 0.45 - 657.3 1 2 0 0.0025 11 0 0 0 1.87E+08 1.02E+08 - - - 4.6799 0.9825 221125_WJC_METTL3_EV_vs_WT_F02.21699.21699.2 6.33E-06 22-Dec K.VIHDNFGIVEGL.M "sp|P04406|G3P_HUMAN,tr|E7EUT5|E7EUT5_HUMAN" 2 1311.6823 - 20597 21699 2 1311.684805 656.8484 Glyceraldehyde-3-phosphate dehydrogenase OS=Homo sapiens OX=9606 GN=GAPDH PE=1 SV=3 4.35 3642.4 - 4.47E+06 - - - 1.9082 - 2.452 0.442 - 619.8 1 1 0 0.0025 12 0 0 0 - - - - - 4.6647 0.9997 221125_WJC_METTL3_EV_vs_WT_F02.21700.21700.2 8.86E-05 20-Dec K.QVQIDGLVVLK[136.11].L "sp|O15372|EIF3H_HUMAN,tr|B3KS98|B3KS98_HUMAN,tr|E5RFW7|E5RFW7_HUMAN,tr|E5RFH0|E5RFH0_HUMAN" 4 1218.7427 1.83 20598 21700 2 1218.744964 610.3786 Eukaryotic translation initiation factor 3 subunit H OS=Homo sapiens OX=9606 GN=EIF3H PE=1 SV=1 5.84 3642.4 - 4.16E+06 - - - 1.838 - 2.247 0.478 - 630.4 1 2 0 0.0022 11 0 0 0 1.87E+08 1.02E+08 - - - 4.761 0.9833 221125_WJC_METTL3_EV_vs_WT_F02.21703.21703.2 1.39E-06 20-Dec Q.NQEYSLLLSIK.M "sp|P35527|K1C9_HUMAN,tr|K7EQQ3|K7EQQ3_HUMAN" 2 1306.7133 -1 20601 21703 2 1306.716611 654.3639 "Keratin, type I cytoskeletal 9 OS=Homo sapiens OX=9606 GN=KRT9 PE=1 SV=3" 6 3642.6 - 2.22E+06 - - - 2.5591 - 2.654 0.537 - 734.1 1 1 0 0.0033 11 0 0 0 0.00E+00 0.00E+00 - - - 5.6467 0.9999 221125_WJC_METTL3_EV_vs_WT_F02.21705.21705.3 1.95E-05 Dec-56 R.NYLEGIYNVPVAAVR.T "sp|Q16540|RM23_HUMAN,tr|H7C2P7|H7C2P7_HUMAN,tr|A8MYK1|A8MYK1_HUMAN,tr|A8MVT4|A8MVT4_HUMAN,tr|A6NJD9|A6NJD9_HUMAN" 5 1676.8886 0.7 20603 21705 3 1676.891454 559.9701 "39S ribosomal protein L23, mitochondrial OS=Homo sapiens OX=9606 GN=MRPL23 PE=1 SV=1" 6 3642.8 - 1.86E+06 - - - 1.6984 - 2.512 0.423 - 146.8 1 2 0 0.0028 15 0 0 0 6.99E+06 9.96E+06 - - - 5.6587 0.9998 221125_WJC_METTL3_EV_vs_WT_F02.21706.21706.2 2.35E-05 13/24 K.TEVLSEDLLQIER.R "sp|Q68EM7|RHG17_HUMAN,tr|I3L1S9|I3L1S9_HUMAN,tr|I3L4P0|I3L4P0_HUMAN,tr|C9IZD3|C9IZD3_HUMAN" 4 1543.8094 1.72 20604 21706 2 1543.812536 772.912 Rho GTPase-activating protein 17 OS=Homo sapiens OX=9606 GN=ARHGAP17 PE=1 SV=1 4 3642.8 - 1.49E+06 - - - 2.0618 - 2.829 0.505 - 506.9 1 2 0 0.0032 13 0 0 0 4.05E+07 2.35E+07 - - - 5.4389 0.9984 221125_WJC_METTL3_EV_vs_WT_F02.21707.21707.3 0.00526 Nov-52 K.LPIGDVATQYFADR[166.11].D sp|Q99832|TCPH_HUMAN 1 1574.7968 0.19 20605 21707 3 1574.799935 525.9396 T-complex protein 1 subunit eta OS=Homo sapiens OX=9606 GN=CCT7 PE=1 SV=2 4.21 3642.9 - 1.24E+06 - - - 1.973 - 1.821 0.298 - 169.4 1 2 0 0.0031 14 0 0 0 1.79E+07 9.21E+07 - - - 3.4544 0.9765 221125_WJC_METTL3_EV_vs_WT_F02.21708.21708.3 8.30E-07 22/72 K.IIAATIENAQPILQIDNAR.L sp|P08779|K1C16_HUMAN 1 2063.1375 999 20606 21708 3 2064.130345 688.7198 "Keratin, type I cytoskeletal 16 OS=Homo sapiens OX=9606 GN=KRT16 PE=1 SV=4" 4.37 3643 - 1.03E+06 - - - 481.2287 - 2.849 0.458 - 502.7 1 2 0 0.9928 19 0 0 0 2.46E+06 0.00E+00 - - - 5.9434 0.9981 221125_WJC_METTL3_EV_vs_WT_F02.21714.21714.2 0.000508 22-Sep R.NVALSGVLEVVR[166.11].A "sp|Q6PJ69|TRI65_HUMAN,tr|H0YGS7|H0YGS7_HUMAN" 2 1264.7379 -1 20612 21714 2 1264.740662 633.3762 Tripartite motif-containing protein 65 OS=Homo sapiens OX=9606 GN=TRIM65 PE=1 SV=3 6 3643.7 - 341982 - - - 2.2186 - 1.841 0.273 - 247.2 1 2 0 0.0028 12 0 0 0 0.00E+00 0.00E+00 - - - 2.6623 0.9983 221125_WJC_METTL3_EV_vs_WT_F02.21721.21721.2 3.68E-08 14/26 K.EISFAYEVLSNPEK[136.11].R sp|O60884|DNJA2_HUMAN 1 1632.8127 3.99 20618 21721 2 1632.820514 817.4136 DnaJ homolog subfamily A member 2 OS=Homo sapiens OX=9606 GN=DNAJA2 PE=1 SV=1 4.25 3644.3 - 2.28E+06 - - - 4.8138 - 2.64 0.51 - 688.1 1 2 0 0.0079 14 0 0 0 8.43E+07 2.11E+07 - - - 5.2415 0.9998 221125_WJC_METTL3_EV_vs_WT_F02.21722.21722.3 0.000418 14/64 R.AATIVATSEGSLWGLDR.V "sp|P13861|KAP2_HUMAN,tr|H7C1L0|H7C1L0_HUMAN" 2 1745.8948 1.96 20619 21722 3 1745.899145 582.9722 cAMP-dependent protein kinase type II-alpha regulatory subunit OS=Homo sapiens OX=9606 GN=PRKAR2A PE=1 SV=2 4.37 3644.3 - 2.11E+06 - - - 2.4807 - 2.614 0.408 - 282.2 1 2 0 0.0043 17 0 0 0 1.88E+07 9.57E+06 - - - 5.5151 0.8967 221125_WJC_METTL3_EV_vs_WT_F02.21723.21723.2 0.00283 20-Aug H.NLQSIFNIGSR.G "sp|P43243|MATR3_HUMAN,tr|A8MXP9|A8MXP9_HUMAN,tr|D6R991|D6R991_HUMAN,tr|D6REK4|D6REK4_HUMAN,tr|A0A0R4J2E8|A0A0R4J2E8_HUMAN,tr|D6RCM3|D6RCM3_HUMAN,tr|D6R8Z5|D6R8Z5_HUMAN,tr|D6REM6|D6REM6_HUMAN" 8 1247.6622 1.46 20620 21723 2 1247.664776 624.8384 Matrin-3 OS=Homo sapiens OX=9606 GN=MATR3 PE=1 SV=2 9.75 3644.4 - 2.05E+06 - - - 2.0366 - 1.625 0.299 - 192.3 1 1 0 0.0025 11 0 0 0 2.09E+07 1.43E+07 - - - 2.562 0.9911 221125_WJC_METTL3_EV_vs_WT_F02.21724.21724.2 0.112 24-Sep K.LSDLLAPISEQIK.E "sp|Q01518|CAP1_HUMAN,tr|Q5T0R6|Q5T0R6_HUMAN,tr|Q5T0R3|Q5T0R3_HUMAN,tr|Q5T0R4|Q5T0R4_HUMAN,tr|Q5T0R2|Q5T0R2_HUMAN,tr|Q5T0R1|Q5T0R1_HUMAN,tr|Q5T0R7|Q5T0R7_HUMAN,tr|Q5T0R5|Q5T0R5_HUMAN,tr|Q5T0R9|Q5T0R9_HUMAN" 9 1425.8079 1.26 20621 21724 2 1425.813334 713.9112 Adenylyl cyclase-associated protein 1 OS=Homo sapiens OX=9606 GN=CAP1 PE=1 SV=5 4.37 3644.4 - 1.70E+06 - - - 3.814 - 1.648 0.268 - 258.2 1 2 0 0.0054 13 0 0 0 1.20E+07 9.54E+06 - - - 2.3009 0.9359 221125_WJC_METTL3_EV_vs_WT_F02.21725.21725.2 0.0144 13/20 H.NLQSIFNIGSR[166.11].G "sp|P43243|MATR3_HUMAN,tr|A8MXP9|A8MXP9_HUMAN,tr|D6R991|D6R991_HUMAN,tr|D6REK4|D6REK4_HUMAN,tr|A0A0R4J2E8|A0A0R4J2E8_HUMAN,tr|D6RCM3|D6RCM3_HUMAN,tr|D6R8Z5|D6R8Z5_HUMAN,tr|D6REM6|D6REM6_HUMAN" 8 1257.6705 1.46 20622 21725 2 1257.674107 629.8425 Matrin-3 OS=Homo sapiens OX=9606 GN=MATR3 PE=1 SV=2 9.75 3644.5 - 1.58E+06 - - - 2.864 - 2.201 0.34 - 713 1 1 0 0.0036 11 0 0 0 2.09E+07 1.43E+07 - - - 3.6853 0.9977 221125_WJC_METTL3_EV_vs_WT_F02.21726.21726.2 0.0119 16-Sep K.VQEIITWLK[136.11].G "sp|Q8IZH2|XRN1_HUMAN,tr|H7C5E4|H7C5E4_HUMAN" 2 1136.6685 1.85 20623 21726 2 1136.671871 569.3415 5'-3' exoribonuclease 1 OS=Homo sapiens OX=9606 GN=XRN1 PE=1 SV=1 5.97 3644.6 - 1.51E+06 - - - 2.9692 - 1.963 0.273 - 277.5 1 2 0 0.0034 9 0 0 0 1.23E+07 6.67E+06 - - - 3.0076 0.9999 221125_WJC_METTL3_EV_vs_WT_F02.21727.21727.3 1.27E-05 13/64 R.AATIVATSEGSLWGLDR[166.11].V "sp|P13861|KAP2_HUMAN,tr|H7C1L0|H7C1L0_HUMAN" 2 1755.9031 1.96 20624 21727 3 1755.907118 586.3083 cAMP-dependent protein kinase type II-alpha regulatory subunit OS=Homo sapiens OX=9606 GN=PRKAR2A PE=1 SV=2 4.37 3644.7 - 1.24E+06 - - - 2.2974 - 2.857 0.466 - 201.7 1 2 0 0.004 17 0 0 0 1.88E+07 9.57E+06 - - - 6.3864 0.9987 221125_WJC_METTL3_EV_vs_WT_F02.21729.21729.2 0.000202 15/24 K.LSDLLAPISEQIK[136.11].E "sp|Q01518|CAP1_HUMAN,tr|Q5T0R6|Q5T0R6_HUMAN,tr|Q5T0R3|Q5T0R3_HUMAN,tr|Q5T0R4|Q5T0R4_HUMAN,tr|Q5T0R2|Q5T0R2_HUMAN,tr|Q5T0R1|Q5T0R1_HUMAN,tr|Q5T0R7|Q5T0R7_HUMAN,tr|Q5T0R5|Q5T0R5_HUMAN,tr|Q5T0R9|Q5T0R9_HUMAN" 9 1433.8221 1.26 20626 21729 2 1433.82749 717.9183 Adenylyl cyclase-associated protein 1 OS=Homo sapiens OX=9606 GN=CAP1 PE=1 SV=5 4.37 3644.9 - 1.15E+06 - - - 3.762 - 2.682 0.384 - 841.6 1 2 0 0.0054 13 0 0 0 1.20E+07 9.54E+06 - - - 4.4076 0.9997 221125_WJC_METTL3_EV_vs_WT_F02.21730.21730.2 9.96E-06 22-Nov K.IC[160.03]ALENELAALR.A "sp|Q15390|MTFR1_HUMAN,tr|H0YBZ4|H0YBZ4_HUMAN" 2 1371.718 0.88 20627 21730 2 1371.721634 686.8663 Mitochondrial fission regulator 1 OS=Homo sapiens OX=9606 GN=MTFR1 PE=1 SV=2 4.53 3645 - 904568 - - - 2.6237 - 2.718 0.487 - 563.5 1 2 0 0.0036 12 0 0 0 9.96E+06 1.14E+07 - - - 5.2677 0.9994 221125_WJC_METTL3_EV_vs_WT_F02.21732.21732.2 3.05E-07 14/24 R.VESPVLPPVLVPR.H "sp|Q99717|SMAD5_HUMAN,sp|Q15797|SMAD1_HUMAN" 2 1400.8391 1.81 20629 21732 2 1400.843034 701.4268 Mothers against decapentaplegic homolog 5 OS=Homo sapiens OX=9606 GN=SMAD5 PE=1 SV=1 5.97 3645.3 - 761021 - - - 2.7819 - 2.465 0.428 - 475.6 1 2 0 0.0039 13 0 0 0 7.83E+06 4.32E+06 - - - 4.5165 0.9986 221125_WJC_METTL3_EV_vs_WT_F02.21737.21737.2 0.000485 20-Oct K.VDLSLPNIGIK[136.11].R "sp|Q03426|KIME_HUMAN,tr|F5GXC0|F5GXC0_HUMAN,tr|F5H163|F5H163_HUMAN,tr|F5H092|F5H092_HUMAN,tr|F5H8H2|F5H8H2_HUMAN,tr|F5H368|F5H368_HUMAN,tr|A0A1W2PS16|A0A1W2PS16_HUMAN" 7 1175.7005 1.11 20633 21737 2 1175.70397 588.8575 Mevalonate kinase OS=Homo sapiens OX=9606 GN=MVK PE=1 SV=1 5.81 3646 - 1.05E+06 - - - 2.931 - 2.295 0.297 - 226.1 1 2 0 0.0034 11 0 0 0 1.47E+07 1.32E+07 - - - 3.4809 1 221125_WJC_METTL3_EV_vs_WT_F02.21738.21738.2 2.08E-14 20/40 K.GAILSEEELAAMSPTAAAVAK.L sp|P12270|TPR_HUMAN 1 2029.0402 3.13 20634 21738 2 2029.045786 1015.5274 Nucleoprotein TPR OS=Homo sapiens OX=9606 GN=TPR PE=1 SV=3 4.25 3646.1 - 604225 - - - 2.7742 - 3.856 0.661 - 1132 1 2 0 0.0056 21 0 0 0 7.69E+06 2.46E+06 - - - 7.2395 0.9998 221125_WJC_METTL3_EV_vs_WT_F02.21739.21739.2 6.43E-05 13/24 R.ILDIDNVDLAMGK[136.11].M sp|O43615|TIM44_HUMAN 1 1423.7472 0.95 20635 21739 2 1423.74853 712.8809 Mitochondrial import inner membrane translocase subunit TIM44 OS=Homo sapiens OX=9606 GN=TIMM44 PE=1 SV=2 3.93 3646.1 - 5.50E+06 - - - 0.9222 - 2.549 0.432 - 514.8 1 2 0 0.0013 13 0 0 0 3.52E+07 3.72E+07 - - - 4.6328 1 221125_WJC_METTL3_EV_vs_WT_F02.21740.21740.2 2.03E-06 13/24 K.TEVLSEDLLQIER[166.11].R "sp|Q68EM7|RHG17_HUMAN,tr|I3L1S9|I3L1S9_HUMAN,tr|I3L4P0|I3L4P0_HUMAN,tr|C9IZD3|C9IZD3_HUMAN" 4 1553.8176 1.74 20636 21740 2 1553.820231 777.9161 Rho GTPase-activating protein 17 OS=Homo sapiens OX=9606 GN=ARHGAP17 PE=1 SV=1 4 3646.2 - 4.12E+06 - - - 1.6784 - 2.792 0.562 - 519 1 2 0 0.0026 13 0 0 0 4.09E+07 2.35E+07 - - - 5.8263 0.9994 221125_WJC_METTL3_EV_vs_WT_F02.21742.21742.2 0.000141 20-Sep R.DPIPYLPPLEK[136.11].L sp|P08621|RU17_HUMAN 1 1288.7158 1.68 20638 21742 2 1288.717798 645.3652 U1 small nuclear ribonucleoprotein 70 kDa OS=Homo sapiens OX=9606 GN=SNRNP70 PE=1 SV=2 4.37 3646.3 - 2.48E+06 - - - 1.5193 - 1.841 0.375 - 272.2 1 2 0 0.002 11 0 0 0 4.61E+07 2.75E+07 - - - 3.4612 0.998 221125_WJC_METTL3_EV_vs_WT_F02.21743.21743.2 1.30E-06 26-Dec K.EISFAYEVLSNPEK.R sp|O60884|DNJA2_HUMAN 1 1624.7985 164.47 20639 21743 2 1624.793595 813.4065 DnaJ homolog subfamily A member 2 OS=Homo sapiens OX=9606 GN=DNAJA2 PE=1 SV=1 4.25 3646.4 - 2.36E+06 - - - -2.9905 - 2.12 0.295 - 345.9 1 2 0 -0.0049 14 0 0 0 7.34E+09 4.46E+07 - - - 3.104 0.9999 221125_WJC_METTL3_EV_vs_WT_F02.21745.21745.3 8.79E-05 16/56 R.LFPLIQAMHPTLAGK[136.11].L "sp|Q9H361|PABP3_HUMAN,sp|P11940|PABP1_HUMAN,tr|H0YAS6|H0YAS6_HUMAN,tr|H0YB75|H0YB75_HUMAN,tr|A0A7I2YQE4|A0A7I2YQE4_HUMAN,tr|A0A7I2V649|A0A7I2V649_HUMAN,tr|H0YAR2|H0YAR2_HUMAN,tr|E7ERJ7|E7ERJ7_HUMAN,tr|A0A7I2YQ88|A0A7I2YQ88_HUMAN,tr|A0A087WTT1|A0A087WTT1_HUMAN,tr|A0A7I2YQ90|A0A7I2YQ90_HUMAN,tr|A0A7I2V4N4|A0A7I2V4N4_HUMAN,tr|E7EQV3|E7EQV3_HUMAN" 13 1643.9313 1.27 20641 21745 3 1643.935891 548.9844 Polyadenylate-binding protein 3 OS=Homo sapiens OX=9606 GN=PABPC3 PE=1 SV=2 8.76 3646.5 - 1.33E+06 - - - 2.8116 - 2.498 0.463 - 232.3 1 2 0 0.0046 15 0 0 0 1.83E+07 1.45E+07 - - - 6.0896 0.9998 221125_WJC_METTL3_EV_vs_WT_F02.21746.21746.3 5.73E-07 16/56 R.LSPISHGNTIALFFR.S sp|Q9BQ70|TCF25_HUMAN 1 1671.9097 0.03 20642 21746 3 1671.915641 558.3105 Transcription factor 25 OS=Homo sapiens OX=9606 GN=TCF25 PE=1 SV=1 9.76 3646.6 - 1.04E+06 - - - 3.5678 - 2.817 0.478 - 397.5 1 2 0 0.006 15 0 0 0 6.84E+06 2.12E+08 - - - 6.57 0.999 221125_WJC_METTL3_EV_vs_WT_F02.21749.21749.3 0.0259 Oct-40 K.QVQIDGLVVLK.L "sp|O15372|EIF3H_HUMAN,tr|B3KS98|B3KS98_HUMAN,tr|E5RFW7|E5RFW7_HUMAN,tr|E5RFH0|E5RFH0_HUMAN" 4 1210.7285 1.47 20645 21749 3 1210.729195 404.5835 Eukaryotic translation initiation factor 3 subunit H OS=Homo sapiens OX=9606 GN=EIF3H PE=1 SV=1 5.84 3646.9 - 615291 - - - 0.5542 - 1.761 0.282 - 120.5 1 2 0 0.0007 11 0 0 0 2.43E+06 1.65E+06 - - - 3.2914 0.9995 221125_WJC_METTL3_EV_vs_WT_F02.21750.21750.2 6.81E-05 22-Sep R.SQPAILLLTAAR.D "sp|Q5JTV8|TOIP1_HUMAN,tr|H0Y4R4|H0Y4R4_HUMAN,tr|J3KN66|J3KN66_HUMAN,tr|A0A0A0MSK5|A0A0A0MSK5_HUMAN" 4 1252.7503 1.19 20646 21750 2 1252.752797 627.3824 Torsin-1A-interacting protein 1 OS=Homo sapiens OX=9606 GN=TOR1AIP1 PE=1 SV=2 9.47 3647.1 - 436205 - - - 1.9757 - 1.969 0.441 - 284.1 1 2 0 0.0025 12 0 0 0 7.32E+06 6.16E+06 - - - 4.0801 0.9978 221125_WJC_METTL3_EV_vs_WT_F02.21751.21751.3 0.0172 Sep-40 K.QVQIDGLVVLK[136.11].L "sp|O15372|EIF3H_HUMAN,tr|B3KS98|B3KS98_HUMAN,tr|E5RFW7|E5RFW7_HUMAN,tr|E5RFH0|E5RFH0_HUMAN" 4 1218.7427 1.53 20647 21751 3 1218.744237 407.2549 Eukaryotic translation initiation factor 3 subunit H OS=Homo sapiens OX=9606 GN=EIF3H PE=1 SV=1 5.84 3647.2 - 377811 - - - 1.2414 - 1.733 0.252 - 95.2 1 2 0 0.0015 11 0 0 0 2.53E+06 1.65E+06 - - - 2.9112 1 221125_WJC_METTL3_EV_vs_WT_F02.21755.21755.2 2.25E-09 17/26 K.LPIGDVATQYFADR.D sp|Q99832|TCPH_HUMAN 1 1564.7886 0.19 20649 21755 2 1564.788139 783.4016 T-complex protein 1 subunit eta OS=Homo sapiens OX=9606 GN=CCT7 PE=1 SV=2 4.21 3647.7 - 3.63E+06 - - - -0.2678 - 2.985 0.679 - 919.8 1 2 0 -0.0004 14 0 0 0 3.18E+07 1.65E+08 - - - 6.8003 1 221125_WJC_METTL3_EV_vs_WT_F02.21756.21756.2 7.59E-06 15/30 R.MIAGQVLDINLAAEPK.V "sp|P07910|HNRPC_HUMAN,tr|G3V251|G3V251_HUMAN,tr|B4DY08|B4DY08_HUMAN,tr|G3V575|G3V575_HUMAN,tr|B4DSU6|B4DSU6_HUMAN,tr|G3V3K6|G3V3K6_HUMAN,tr|B2R5W2|B2R5W2_HUMAN,tr|G3V4C1|G3V4C1_HUMAN,tr|G3V576|G3V576_HUMAN,tr|G3V5X6|G3V5X6_HUMAN,tr|G3V4W0|G3V4W0_HUMAN,tr|G3V555|G3V555_HUMAN,tr|G3V2Q1|G3V2Q1_HUMAN" 13 1681.9073 1.56 20650 21756 2 1681.906069 841.9609 Heterogeneous nuclear ribonucleoproteins C1\C2 OS=Homo sapiens OX=9606 GN=HNRNPC PE=1 SV=4 4.37 3647.8 - 3.31E+06 - - - -0.7277 - 3.36 0.544 - 446.1 1 2 0 -0.0012 16 0 0 0 1.64E+09 1.05E+09 - - - 6.0382 0.9999 221125_WJC_METTL3_EV_vs_WT_F02.21757.21757.2 3.74E-07 15/28 R.LDLDLTADSQPPVFK[136.11].V "sp|Q13263|TIF1B_HUMAN,tr|M0R0K9|M0R0K9_HUMAN" 2 1665.8705 0.25 20651 21757 2 1665.870071 833.9425 Transcription intermediary factor 1-beta OS=Homo sapiens OX=9606 GN=TRIM28 PE=1 SV=5 3.93 3647.8 - 2.90E+06 - - - -0.2593 - 2.837 0.541 - 530.6 1 2 0 -0.0004 15 0 0 0 2.04E+07 8.19E+07 - - - 5.6003 0.9999 221125_WJC_METTL3_EV_vs_WT_F02.21758.21758.2 2.14E-07 20-Nov R.GWDEALLTMSK[136.11].G sp|Q00688|FKBP3_HUMAN 1 1257.6155 0.14 20652 21758 2 1257.616452 629.815 Peptidyl-prolyl cis-trans isomerase FKBP3 OS=Homo sapiens OX=9606 GN=FKBP3 PE=1 SV=1 4.37 3647.9 - 2.60E+06 - - - 0.7777 - 2.232 0.549 - 523.2 1 2 0 0.001 11 0 0 0 3.44E+06 2.39E+07 - - - 5.2676 0.9999 221125_WJC_METTL3_EV_vs_WT_F02.21760.21760.3 0.00161 15/60 R.MIAGQVLDINLAAEPK[136.11].V "sp|P07910|HNRPC_HUMAN,tr|G3V251|G3V251_HUMAN,tr|B4DY08|B4DY08_HUMAN,tr|G3V575|G3V575_HUMAN,tr|B4DSU6|B4DSU6_HUMAN,tr|G3V3K6|G3V3K6_HUMAN,tr|B2R5W2|B2R5W2_HUMAN,tr|G3V4C1|G3V4C1_HUMAN,tr|G3V576|G3V576_HUMAN,tr|G3V5X6|G3V5X6_HUMAN,tr|G3V4W0|G3V4W0_HUMAN,tr|G3V555|G3V555_HUMAN,tr|G3V2Q1|G3V2Q1_HUMAN" 13 1689.9215 1.62 20654 21760 3 1689.922551 564.3144 Heterogeneous nuclear ribonucleoproteins C1\C2 OS=Homo sapiens OX=9606 GN=HNRNPC PE=1 SV=4 4.37 3648 - 1.99E+06 - - - 0.6261 - 2.936 0.385 - 282.2 1 2 0 0.0011 16 0 0 0 8.93E+08 5.53E+08 - - - 5.5956 0.9993 221125_WJC_METTL3_EV_vs_WT_F02.21762.21762.2 0.0019 14/22 R.ALLLQQLQGNLR.G tr|H0Y5D5|H0Y5D5_HUMAN 1 1365.8092 3.33 20656 21762 2 1365.81299 683.9119 Cip1-interacting zinc finger protein (Fragment) OS=Homo sapiens OX=9606 GN=CIZ1 PE=1 SV=1 9.79 3648.2 - 1.67E+06 - - - 2.7508 - 2.563 0.371 - 857.8 1 2 0 0.0038 12 0 0 0 1.51E+07 4.53E+06 - - - 4.2564 0.9999 221125_WJC_METTL3_EV_vs_WT_F02.21763.21763.2 5.46E-05 15/24 K.GISLNPEQWSQLK.E sp|P53999|TCP4_HUMAN 1 1498.778 0.28 20657 21763 2 1498.778503 750.3963 Activated RNA polymerase II transcriptional coactivator p15 OS=Homo sapiens OX=9606 GN=SUB1 PE=1 SV=3 6 3648.3 - 1.32E+06 - - - 0.3403 - 2.826 0.533 - 710.4 1 2 0 0.0005 13 0 0 0 2.67E+07 9.49E+07 - - - 5.6438 0.9733 221125_WJC_METTL3_EV_vs_WT_F02.21764.21764.3 4.35E-05 Nov-52 K.SFYPEEVSSMVLTK[136.11].M "sp|P11142|HSP7C_HUMAN,tr|E9PQQ4|E9PQQ4_HUMAN,tr|E9PKE3|E9PKE3_HUMAN,tr|E9PN89|E9PN89_HUMAN,tr|E9PLF4|E9PLF4_HUMAN,tr|E9PI65|E9PI65_HUMAN,tr|E9PK54|E9PK54_HUMAN,tr|E9PN25|E9PN25_HUMAN,tr|E9PPY6|E9PPY6_HUMAN,tr|E9PQK7|E9PQK7_HUMAN" 10 1623.7946 0.15 20658 21764 3 1624.798163 542.2721 Heat shock cognate 71 kDa protein OS=Homo sapiens OX=9606 GN=HSPA8 PE=1 SV=1 4.53 3648.4 - 1.04E+06 - - - 618.0597 - 1.947 0.287 - 158.9 1 2 0 1.0036 14 0 0 0 3.77E+08 2.53E+09 - - - 3.2325 1 221125_WJC_METTL3_EV_vs_WT_F02.21767.21767.2 2.14E-08 17/30 R.LVEDNPSSLSLVEIYK.Q "sp|Q9Y4A5|TRRAP_HUMAN,tr|A0A2R8YFJ4|A0A2R8YFJ4_HUMAN,tr|H0Y4W2|H0Y4W2_HUMAN,tr|F2Z2U4|F2Z2U4_HUMAN" 4 1804.9458 0.99 20661 21767 2 1804.946152 903.4802 Transformation\transcription domain-associated protein OS=Homo sapiens OX=9606 GN=TRRAP PE=1 SV=3 4.14 3648.7 - 722317 - - - 0.1695 - 3.608 0.632 - 780.1 1 2 0 0.0003 16 0 0 0 1.20E+07 1.21E+07 - - - 6.8635 0.9988 221125_WJC_METTL3_EV_vs_WT_F02.21768.21768.3 0.00181 Nov-48 K.VISDKDLELLLDR.S "sp|Q9NRZ9|HELLS_HUMAN,tr|Q9NW36|Q9NW36_HUMAN,tr|A0A087WSW7|A0A087WSW7_HUMAN,tr|A0A0B4J1V9|A0A0B4J1V9_HUMAN,tr|F6XU50|F6XU50_HUMAN" 5 1527.8508 0.89 20662 21768 3 1527.851594 510.2909 Lymphoid-specific helicase OS=Homo sapiens OX=9606 GN=HELLS PE=1 SV=1 4.23 3648.9 - 655388 - - - 0.504 - 2.264 0.324 - 158.9 1 2 1 0.0008 13 0 0 0 3.75E+06 4.20E+06 - - - 4.3676 0.9994 221125_WJC_METTL3_EV_vs_WT_F02.21770.21770.2 0.000949 18-Oct K.SMDLSEYIIR.G "sp|Q9H0A0|NAT10_HUMAN,tr|A0A087WV29|A0A087WV29_HUMAN" 2 1225.6013 0.62 20664 21770 2 1225.598027 613.8079 RNA cytidine acetyltransferase OS=Homo sapiens OX=9606 GN=NAT10 PE=1 SV=2 4.37 3649.1 - 514913 - - - -2.6493 - 2.004 0.452 - 277.5 1 2 0 -0.0032 10 0 0 0 2.75E+06 4.42E+06 - - - 4.3188 0.9995 221125_WJC_METTL3_EV_vs_WT_F02.21771.21771.3 0.00195 13/44 K.LSEVTFR[166.11]PLFFK[136.11].L "sp|Q9H583|HEAT1_HUMAN,tr|Q5T3Q7|Q5T3Q7_HUMAN" 2 1500.846 1.57 20665 21771 3 1500.84749 501.2893 HEAT repeat-containing protein 1 OS=Homo sapiens OX=9606 GN=HEATR1 PE=1 SV=3 8.75 3649.2 - 379716 - - - 1.0214 - 2.183 0.284 - 149.5 1 2 0 0.0015 12 0 0 0 3.42E+06 2.18E+06 - - - 3.8699 0.9999 221125_WJC_METTL3_EV_vs_WT_F02.21777.21777.2 1.21E-08 14/26 K.YFYVSAEQVVQGMK.E sp|O95881|TXD12_HUMAN 1 1647.7967 1.17 20669 21777 2 1647.795058 824.9056 Thioredoxin domain-containing protein 12 OS=Homo sapiens OX=9606 GN=TXNDC12 PE=1 SV=1 6 3650 - 1.21E+07 - - - -0.9843 - 2.347 0.593 - 512.8 1 2 0 -0.0016 14 0 0 0 1.50E+08 1.28E+08 - - - 5.5613 1 221125_WJC_METTL3_EV_vs_WT_F02.21778.21778.2 2.49E-09 26-Dec K.YFYVSAEQVVQGMK[136.11].E sp|O95881|TXD12_HUMAN 1 1655.8109 1.22 20670 21778 2 1655.812002 828.9127 Thioredoxin domain-containing protein 12 OS=Homo sapiens OX=9606 GN=TXNDC12 PE=1 SV=1 6 3650 - 1.05E+07 - - - 0.6776 - 2.424 0.664 - 393.5 1 2 0 0.0011 14 0 0 0 1.50E+08 1.23E+08 - - - 6.1669 0.9999 221125_WJC_METTL3_EV_vs_WT_F02.21779.21779.3 2.58E-07 Nov-52 K.YFYVSAEQVVQGMK.E sp|O95881|TXD12_HUMAN 1 1647.7967 1.31 20671 21779 3 1647.801256 550.2728 Thioredoxin domain-containing protein 12 OS=Homo sapiens OX=9606 GN=TXNDC12 PE=1 SV=1 6 3650.1 - 5.51E+06 - - - 2.777 - 2.398 0.592 - 178.7 1 2 0 0.0046 14 0 0 0 5.15E+07 3.93E+07 - - - 7.4633 1 221125_WJC_METTL3_EV_vs_WT_F02.21780.21780.3 2.02E-06 Oct-52 K.YFYVSAEQVVQGMK[136.11].E sp|O95881|TXD12_HUMAN 1 1655.8109 1.33 20672 21780 3 1655.812854 552.9442 Thioredoxin domain-containing protein 12 OS=Homo sapiens OX=9606 GN=TXNDC12 PE=1 SV=1 6 3650.1 - 5.27E+06 - - - 1.1922 - 2.225 0.549 - 118.7 1 2 0 0.002 14 0 0 0 5.15E+07 3.88E+07 - - - 6.7856 0.9999 221125_WJC_METTL3_EV_vs_WT_F02.21782.21782.2 7.34E-07 13/26 K.TTLLEGFAGVEEAR.E "sp|P35658|NU214_HUMAN,tr|A0A0A0MSW3|A0A0A0MSW3_HUMAN,tr|A0A494BZU9|A0A494BZU9_HUMAN,tr|A0A494C1F2|A0A494C1F2_HUMAN" 4 1491.7569 0.8 20674 21782 2 1491.758596 746.8857 Nuclear pore complex protein Nup214 OS=Homo sapiens OX=9606 GN=NUP214 PE=1 SV=2 4.25 3650.2 - 4.30E+06 - - - 1.1215 - 2.333 0.604 - 532.2 1 2 0 0.0017 14 0 0 0 1.02E+08 1.27E+08 - - - 5.6275 1 221125_WJC_METTL3_EV_vs_WT_F02.21783.21783.3 5.42E-08 14/52 K.LWSVPDC[160.03]NLLHTLR.G sp|O43172|PRP4_HUMAN 1 1722.8876 2.66 20675 21783 3 1722.890894 575.3031 U4\U6 small nuclear ribonucleoprotein Prp4 OS=Homo sapiens OX=9606 GN=PRPF4 PE=1 SV=2 6.74 3650.3 - 3.41E+06 - - - 1.9351 - 2.821 0.561 - 328.9 1 2 0 0.0033 14 0 0 0 3.42E+07 1.29E+07 - - - 7.5498 1 221125_WJC_METTL3_EV_vs_WT_F02.21786.21786.3 6.00E-07 17/68 R.VNPC[160.03]IGGVILFHETLYQK.A "sp|P04075|ALDOA_HUMAN,tr|H3BR04|H3BR04_HUMAN,tr|H3BMQ8|H3BMQ8_HUMAN,tr|H3BU78|H3BU78_HUMAN,tr|H3BQN4|H3BQN4_HUMAN,tr|H3BUH7|H3BUH7_HUMAN,tr|J3KPS3|J3KPS3_HUMAN,tr|H3BPS8|H3BPS8_HUMAN" 8 2087.0874 2.07 20678 21786 3 2087.091051 696.7031 Fructose-bisphosphate aldolase A OS=Homo sapiens OX=9606 GN=ALDOA PE=1 SV=2 6.71 3650.5 - 1.73E+06 - - - 1.7575 - 3.352 0.505 - 282.9 1 2 0 0.0037 18 0 0 0 9.45E+06 4.56E+06 - - - 7.1812 1 221125_WJC_METTL3_EV_vs_WT_F02.21790.21790.2 8.90E-08 26-Dec K.VYEIQDIYENSWTK.L "sp|Q9Y262|EIF3L_HUMAN,tr|B0QY89|B0QY89_HUMAN,tr|C9K0Q7|C9K0Q7_HUMAN,tr|C9JHP4|C9JHP4_HUMAN" 4 1786.8414 1.61 20682 21790 2 1786.839572 894.428 Eukaryotic translation initiation factor 3 subunit L OS=Homo sapiens OX=9606 GN=EIF3L PE=1 SV=1 4.14 3651 - 1.05E+06 - - - -1.0124 - 2.814 0.624 - 369.8 1 2 0 -0.0018 14 0 0 0 9.33E+06 5.79E+06 - - - 6.2456 0.9993 221125_WJC_METTL3_EV_vs_WT_F02.21795.21795.3 0.0132 14/48 K.EAEAMALLAEAER[166.11].K "sp|P54920|SNAA_HUMAN,tr|M0QZN5|M0QZN5_HUMAN,tr|M0R2M1|M0R2M1_HUMAN,tr|M0R031|M0R031_HUMAN,tr|M0QZM9|M0QZM9_HUMAN,tr|M0R0Y2|M0R0Y2_HUMAN" 6 1412.6845 0.89 20687 21795 3 1412.683196 471.9021 Alpha-soluble NSF attachment protein OS=Homo sapiens OX=9606 GN=NAPA PE=1 SV=3 4.09 3651.6 - 528872 - - - -0.9231 - 2.199 0.258 - 278.3 1 2 0 -0.0013 13 0 0 0 1.87E+06 2.11E+06 - - - 3.5526 0.987 221125_WJC_METTL3_EV_vs_WT_F02.21796.21796.3 0.0856 Oct-48 R.NLEASAVIQGLVK.D sp|Q8IWA0|WDR75_HUMAN 1 1340.7664 0.48 20688 21796 3 1340.767624 447.9294 WD repeat-containing protein 75 OS=Homo sapiens OX=9606 GN=WDR75 PE=1 SV=1 6 3651.7 - 492179 - - - 0.9383 - 1.65 0.161 - 133 1 2 0 0.0013 13 0 0 0 2.21E+06 4.58E+06 - - - 1.6924 0.9997 221125_WJC_METTL3_EV_vs_WT_F02.21798.21798.2 0.000782 20-Sep R.DPIPYLPPLEK.L sp|P08621|RU17_HUMAN 1 1280.7016 1.68 20689 21798 2 1280.70264 641.3581 U1 small nuclear ribonucleoprotein 70 kDa OS=Homo sapiens OX=9606 GN=SNRNP70 PE=1 SV=2 4.37 3652 - 2.76E+06 - - - 0.7808 - 1.889 0.406 - 259.6 1 2 0 0.001 11 0 0 0 4.58E+07 2.73E+07 - - - 3.7601 1 221125_WJC_METTL3_EV_vs_WT_F02.21800.21800.2 4.89E-06 14/26 K.LISWYDNEFGYSNR[166.11].V "sp|P04406|G3P_HUMAN,tr|E7EUT5|E7EUT5_HUMAN" 2 1772.8034 1.05 20691 21800 2 1772.801707 887.409 Glyceraldehyde-3-phosphate dehydrogenase OS=Homo sapiens OX=9606 GN=GAPDH PE=1 SV=3 4.37 3652.2 - 3.58E+06 - - - -0.9381 - 2.687 0.654 - 754.5 1 2 0 -0.0017 14 0 0 0 5.81E+09 5.51E+09 - - - 6.3513 0.9999 221125_WJC_METTL3_EV_vs_WT_F02.21801.21801.3 4.72E-05 Dec-56 R.LDLDLTADSQPPVFK[136.11].V "sp|Q13263|TIF1B_HUMAN,tr|M0R0K9|M0R0K9_HUMAN" 2 1665.8705 0.3 20692 21801 3 1665.871898 556.2974 Transcription intermediary factor 1-beta OS=Homo sapiens OX=9606 GN=TRIM28 PE=1 SV=5 3.93 3652.2 - 3.00E+06 - - - 0.8374 - 2.193 0.445 - 166.3 1 2 0 0.0014 15 0 0 0 6.52E+06 2.18E+07 - - - 5.55 1 221125_WJC_METTL3_EV_vs_WT_F02.21802.21802.2 8.64E-07 16/30 R.LVEDNPSSLSLVEIYK[136.11].Q "sp|Q9Y4A5|TRRAP_HUMAN,tr|A0A2R8YFJ4|A0A2R8YFJ4_HUMAN,tr|H0Y4W2|H0Y4W2_HUMAN,tr|F2Z2U4|F2Z2U4_HUMAN" 4 1812.96 0.99 20693 21802 2 1812.959203 907.4873 Transformation\transcription domain-associated protein OS=Homo sapiens OX=9606 GN=TRRAP PE=1 SV=3 4.14 3652.4 - 2.09E+06 - - - -0.465 - 3.576 0.603 - 661.1 1 2 0 -0.0008 16 0 0 0 1.20E+07 1.21E+07 - - - 6.6273 0.9998 221125_WJC_METTL3_EV_vs_WT_F02.21803.21803.2 0.000241 13/22 K.LQSTFVFEEIGR[166.11].R "sp|P51659|DHB4_HUMAN,tr|A0A2R8Y7L2|A0A2R8Y7L2_HUMAN,tr|A0A2R8YD50|A0A2R8YD50_HUMAN,tr|A0A804HIR1|A0A804HIR1_HUMAN,tr|E7ET17|E7ET17_HUMAN,tr|E7EPL9|E7EPL9_HUMAN,tr|A0A804HK65|A0A804HK65_HUMAN" 7 1434.7383 0.57 20694 21803 2 1434.737977 718.3764 Peroxisomal multifunctional enzyme type 2 OS=Homo sapiens OX=9606 GN=HSD17B4 PE=1 SV=3 4.53 3652.4 - 2.08E+06 - - - -0.1903 - 2.44 0.417 - 813.3 1 2 0 -0.0003 12 0 0 0 1.06E+07 1.87E+07 - - - 4.4679 0.9998 221125_WJC_METTL3_EV_vs_WT_F02.21805.21805.3 0.261 Nov-52 K.LPIGDVATQYFADR.D sp|Q99832|TCPH_HUMAN 1 1564.7886 0.2 20696 21805 3 1564.788211 522.6035 T-complex protein 1 subunit eta OS=Homo sapiens OX=9606 GN=CCT7 PE=1 SV=2 4.21 3652.6 - 1.91E+06 - - - -0.2218 - 1.921 0.384 - 136.2 1 2 0 -0.0003 14 0 0 0 8.67E+06 4.30E+07 - - - 4.5561 0.9997 221125_WJC_METTL3_EV_vs_WT_F02.21806.21806.2 3.85E-07 22-Dec K.C[160.03]PQIVIAFYEER[166.11].L "sp|P45973|CBX5_HUMAN,sp|Q13185|CBX3_HUMAN" 2 1533.7525 0.46 20697 21806 2 1533.749802 767.8835 Chromobox protein homolog 5 OS=Homo sapiens OX=9606 GN=CBX5 PE=1 SV=1 4.53 3652.7 - 1.89E+06 - - - -1.7721 - 2.856 0.345 - 618.3 1 2 0 -0.0027 12 0 0 0 6.38E+06 1.40E+07 - - - 4.3495 0.9998 221125_WJC_METTL3_EV_vs_WT_F02.21807.21807.3 5.26E-05 23/84 R.EALGLGPPAAQLTPPPAPVGLR[166.11].G "sp|Q8IY67|RAVR1_HUMAN,tr|E9PAU2|E9PAU2_HUMAN,tr|A0A087WZ13|A0A087WZ13_HUMAN" 3 2131.2029 1.32 20698 21807 3 2131.201016 711.4082 Ribonucleoprotein PTB-binding 1 OS=Homo sapiens OX=9606 GN=RAVER1 PE=1 SV=1 6.1 3652.8 - 1.61E+06 - - - -0.8817 - 3.776 0.27 - 476.1 1 2 0 -0.0019 22 0 0 0 1.89E+07 1.43E+07 - - - 4.6998 0.9996 221125_WJC_METTL3_EV_vs_WT_F02.21809.21809.2 0.0544 20-Nov K.VDLSLPNIGIK.R "sp|Q03426|KIME_HUMAN,tr|F5GXC0|F5GXC0_HUMAN,tr|F5H163|F5H163_HUMAN,tr|F5H092|F5H092_HUMAN,tr|F5H8H2|F5H8H2_HUMAN,tr|F5H368|F5H368_HUMAN,tr|A0A1W2PS16|A0A1W2PS16_HUMAN" 7 1167.6863 1.11 20700 21809 2 1167.686148 584.8504 Mevalonate kinase OS=Homo sapiens OX=9606 GN=MVK PE=1 SV=1 5.81 3652.9 - 1.29E+06 - - - -0.1507 - 1.956 0.341 - 190.1 1 2 0 -0.0002 11 0 0 0 1.47E+07 1.32E+07 - - - 3.3745 0.9928 221125_WJC_METTL3_EV_vs_WT_F02.21811.21811.2 1.35E-06 30-Nov R.EFAATNSYLGYFGDAK.S "sp|Q2KHR3|QSER1_HUMAN,tr|A0A3B3IRW6|A0A3B3IRW6_HUMAN,tr|H0YCQ7|H0YCQ7_HUMAN" 3 1752.7995 5.12 20702 21811 2 1752.810953 877.407 Glutamine and serine-rich protein 1 OS=Homo sapiens OX=9606 GN=QSER1 PE=1 SV=3 4.37 3653.2 - 869540 - - - 6.525 - 2.028 0.527 - 245 1 2 0 0.0114 16 0 0 0 4.73E+06 9.25E+05 - - - 4.6681 0.9999 221125_WJC_METTL3_EV_vs_WT_F02.21813.21813.3 3.69E-06 13/44 K.C[160.03]PQIVIAFYEER.L "sp|P45973|CBX5_HUMAN,sp|Q13185|CBX3_HUMAN" 2 1523.7442 0.98 20704 21813 3 1523.740271 508.922 Chromobox protein homolog 5 OS=Homo sapiens OX=9606 GN=CBX5 PE=1 SV=1 4.53 3653.4 - 763358 - - - -2.6113 - 2.57 0.511 - 254.4 1 2 0 -0.004 12 0 0 0 4.18E+06 4.25E+06 - - - 6.8524 0.999 221125_WJC_METTL3_EV_vs_WT_F02.21816.21816.2 0.000929 Aug-40 K.GAILSEEELAAMSPTAAAVAK[136.11].L sp|P12270|TPR_HUMAN 1 2037.0544 2.93 20707 21816 2 2037.056691 1019.5345 Nucleoprotein TPR OS=Homo sapiens OX=9606 GN=TPR PE=1 SV=3 4.25 3653.8 - 0 - - - 1.1458 - 1.553 0.342 - 110.9 1 2 0 0.0023 21 0 0 0 7.22E+06 2.46E+06 - - - 2.6485 0.9999 221125_WJC_METTL3_EV_vs_WT_F02.21818.21818.2 1.68E-05 18-Nov K.FAAQELIEVK[136.11].R "sp|Q86U44|MTA70_HUMAN,tr|F5H6D8|F5H6D8_HUMAN,tr|H0YFV6|H0YFV6_HUMAN,tr|B4DTN4|B4DTN4_HUMAN" 4 1154.6427 0.02 20708 21818 2 1154.64184 578.3286 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 4.53 3654 - 5.51E+07 - - - -0.7232 - 2.142 0.501 - 335.1 1 2 0 -0.0008 10 0 0 0 5.35E+07 2.33E+09 - - - 4.8674 1 221125_WJC_METTL3_EV_vs_WT_F02.21819.21819.2 8.45E-08 13/26 K.LISWYDNEFGYSNR.V "sp|P04406|G3P_HUMAN,tr|E7EUT5|E7EUT5_HUMAN" 2 1762.7951 1.05 20709 21819 2 1762.793606 882.4048 Glyceraldehyde-3-phosphate dehydrogenase OS=Homo sapiens OX=9606 GN=GAPDH PE=1 SV=3 4.37 3654 - 1.93E+07 - - - -0.8475 - 2.674 0.689 - 672.3 1 2 0 -0.0015 14 0 0 0 5.81E+09 5.51E+09 - - - 6.5977 0.9999 221125_WJC_METTL3_EV_vs_WT_F02.21820.21820.2 1.91E-09 26-Nov K.SFYPEEVSSMVLTK[136.11].M "sp|P11142|HSP7C_HUMAN,tr|E9PQQ4|E9PQQ4_HUMAN,tr|E9PKE3|E9PKE3_HUMAN,tr|E9PN89|E9PN89_HUMAN,tr|E9PLF4|E9PLF4_HUMAN,tr|E9PI65|E9PI65_HUMAN,tr|E9PK54|E9PK54_HUMAN,tr|E9PN25|E9PN25_HUMAN,tr|E9PPY6|E9PPY6_HUMAN,tr|E9PQK7|E9PQK7_HUMAN" 10 1623.7946 0.16 20710 21820 2 1623.794244 812.9046 Heat shock cognate 71 kDa protein OS=Homo sapiens OX=9606 GN=HSPA8 PE=1 SV=1 4.53 3654.1 - 3.11E+07 - - - -0.1952 - 2.046 0.627 - 271.5 1 2 0 -0.0003 14 0 0 0 1.50E+09 9.60E+09 - - - 5.4684 1 221125_WJC_METTL3_EV_vs_WT_F02.21825.21825.3 4.21E-07 15/52 K.TTLLEGFAGVEEAR.E "sp|P35658|NU214_HUMAN,tr|A0A0A0MSW3|A0A0A0MSW3_HUMAN,tr|A0A494BZU9|A0A494BZU9_HUMAN,tr|A0A494C1F2|A0A494C1F2_HUMAN" 4 1491.7569 1.22 20715 21825 3 1491.756529 498.2596 Nuclear pore complex protein Nup214 OS=Homo sapiens OX=9606 GN=NUP214 PE=1 SV=2 4.25 3654.3 - 3.44E+06 - - - -0.2641 - 2.513 0.551 - 263.7 1 2 0 -0.0004 14 0 0 0 1.79E+07 1.47E+07 - - - 7.1319 0.9997 221125_WJC_METTL3_EV_vs_WT_F02.21826.21826.3 1.46E-05 Dec-52 R.YIQPWESEFIDSQR.V sp|Q6P2Q9|PRP8_HUMAN 1 1796.837 0.82 20716 21826 3 1796.838832 599.9529 Pre-mRNA-processing-splicing factor 8 OS=Homo sapiens OX=9606 GN=PRPF8 PE=1 SV=2 4.14 3654.4 - 3.21E+06 - - - 1.0396 - 2.277 0.323 - 234.5 1 2 0 0.0019 14 0 0 0 1.56E+07 1.91E+07 - - - 4.3274 0.9999 221125_WJC_METTL3_EV_vs_WT_F02.21827.21827.3 0.00863 16/52 R.YIQPWESEFIDSQR[166.11].V sp|Q6P2Q9|PRP8_HUMAN 1 1806.8452 0.75 20717 21827 3 1806.84289 603.289 Pre-mRNA-processing-splicing factor 8 OS=Homo sapiens OX=9606 GN=PRPF8 PE=1 SV=2 4.14 3654.4 - 2.92E+06 - - - -1.2973 - 2.536 0.424 - 408.3 1 2 0 -0.0023 14 0 0 0 1.56E+07 2.07E+07 - - - 5.7396 1 221125_WJC_METTL3_EV_vs_WT_F02.21828.21828.2 1.28E-07 18/26 K.LLDAVDTYIPVPAR[166.11].D sp|P49411|EFTU_HUMAN 1 1551.8536 1.67 20718 21828 2 1551.858434 776.9341 "Elongation factor Tu, mitochondrial OS=Homo sapiens OX=9606 GN=TUFM PE=1 SV=2" 4.21 3654.6 - 2.46E+06 - - - 3.106 - 3.131 0.579 - 1226.9 1 2 0 0.0048 14 0 0 0 1.02E+08 6.09E+07 - - - 6.1801 1 221125_WJC_METTL3_EV_vs_WT_F02.21829.21829.2 4.37E-09 13/26 R.YIQPWESEFIDSQR[166.11].V sp|Q6P2Q9|PRP8_HUMAN 1 1806.8452 2.35 20719 21829 2 1806.839764 904.4299 Pre-mRNA-processing-splicing factor 8 OS=Homo sapiens OX=9606 GN=PRPF8 PE=1 SV=2 4.14 3654.7 - 2.08E+06 - - - -3.0274 - 2.614 0.587 - 542.6 1 2 0 -0.0055 14 0 0 0 2.72E+07 1.16E+07 - - - 5.7861 0.9999 221125_WJC_METTL3_EV_vs_WT_F02.21830.21830.2 5.82E-06 14/24 R.SGGPVVVLVQLER.E sp|O75643|U520_HUMAN 1 1351.7823 2.11 20720 21830 2 1351.782749 676.8985 U5 small nuclear ribonucleoprotein 200 kDa helicase OS=Homo sapiens OX=9606 GN=SNRNP200 PE=1 SV=2 5.72 3654.8 - 1.78E+06 - - - 0.2952 - 2.642 0.494 - 711.7 1 2 0 0.0004 13 0 0 0 2.52E+07 1.20E+07 - - - 5.183 0.9996 221125_WJC_METTL3_EV_vs_WT_F02.21831.21831.2 5.69E-07 14/28 R.VGPDVVTDPAFLVTR[166.11].S sp|Q9NV31|IMP3_HUMAN 1 1594.8594 2.66 20721 21831 2 1594.863832 798.437 U3 small nucleolar ribonucleoprotein protein IMP3 OS=Homo sapiens OX=9606 GN=IMP3 PE=1 SV=1 4.21 3654.9 - 1.71E+06 - - - 2.7614 - 2.468 0.546 - 417.7 1 2 0 0.0044 15 0 0 0 3.74E+07 1.41E+07 - - - 5.2934 1 221125_WJC_METTL3_EV_vs_WT_F02.21832.21832.3 6.98E-07 Dec-44 K.C[160.03]PQIVIAFYEER[166.11].L "sp|P45973|CBX5_HUMAN,sp|Q13185|CBX3_HUMAN" 2 1533.7525 1 20722 21832 3 1533.751742 512.2581 Chromobox protein homolog 5 OS=Homo sapiens OX=9606 GN=CBX5 PE=1 SV=1 4.53 3655 - 877830 - - - -0.5073 - 2.493 0.494 - 243.5 1 2 0 -0.0008 12 0 0 0 3.80E+06 3.82E+06 - - - 6.5794 1 221125_WJC_METTL3_EV_vs_WT_F02.21835.21835.2 1.03E-06 16/26 K.LPIGDVATQYFADR[166.11].D sp|Q99832|TCPH_HUMAN 1 1574.7968 0.21 20724 21835 2 1574.795476 788.4057 T-complex protein 1 subunit eta OS=Homo sapiens OX=9606 GN=CCT7 PE=1 SV=2 4.21 3655.4 - 4.46E+07 - - - -0.8585 - 3.017 0.617 - 841.4 1 2 0 -0.0014 14 0 0 0 1.10E+08 5.12E+08 - - - 6.3688 0.9998 221125_WJC_METTL3_EV_vs_WT_F02.21836.21836.2 8.99E-05 22-Nov R.ELLQDIGDTLSR.A sp|P14373|TRI27_HUMAN 1 1358.7042 1.53 20725 21836 2 1358.703597 680.3594 Zinc finger protein RFP OS=Homo sapiens OX=9606 GN=TRIM27 PE=1 SV=1 4.03 3655.5 - 2.57E+06 - - - -0.4136 - 2.222 0.431 - 569.9 1 2 0 -0.0006 12 0 0 0 3.84E+07 2.51E+07 - - - 4.3249 1 221125_WJC_METTL3_EV_vs_WT_F02.21837.21837.3 0.00214 Dec-52 K.LISWYDNEFGYSNR[166.11].V "sp|P04406|G3P_HUMAN,tr|E7EUT5|E7EUT5_HUMAN" 2 1772.8034 1.08 20726 21837 3 1772.80155 591.9417 Glyceraldehyde-3-phosphate dehydrogenase OS=Homo sapiens OX=9606 GN=GAPDH PE=1 SV=3 4.37 3655.5 - 2.73E+07 - - - -1.0266 - 2.166 0.52 - 181.3 1 2 0 -0.0018 14 0 0 0 1.26E+09 1.17E+09 - - - 6.3909 1 221125_WJC_METTL3_EV_vs_WT_F02.21838.21838.3 1.06E-06 Nov-52 K.LISWYDNEFGYSNR.V "sp|P04406|G3P_HUMAN,tr|E7EUT5|E7EUT5_HUMAN" 2 1762.7951 1.08 20727 21838 3 1762.794855 588.6056 Glyceraldehyde-3-phosphate dehydrogenase OS=Homo sapiens OX=9606 GN=GAPDH PE=1 SV=3 4.37 3655.5 - 2.25E+07 - - - -0.139 - 2.222 0.606 - 154.1 1 2 0 -0.0002 14 0 0 0 1.26E+09 1.17E+09 - - - 7.418 0.9998 221125_WJC_METTL3_EV_vs_WT_F02.21840.21840.2 4.03E-08 16/26 K.TLGFNLESGWGSGR.A "sp|Q14527|HLTF_HUMAN,tr|A0A0C4DGA6|A0A0C4DGA6_HUMAN" 2 1479.7106 1.73 20729 21840 2 1479.710975 740.8626 Helicase-like transcription factor OS=Homo sapiens OX=9606 GN=HLTF PE=1 SV=2 5.66 3655.7 - 2.34E+06 - - - 0.225 - 2.757 0.397 - 821.2 1 2 0 0.0003 14 0 0 0 5.45E+07 3.16E+07 - - - 4.5181 0.9999 221125_WJC_METTL3_EV_vs_WT_F02.21843.21843.3 0.000103 14/52 K.TTLLEGFAGVEEAR[166.11].E "sp|P35658|NU214_HUMAN,tr|A0A0A0MSW3|A0A0A0MSW3_HUMAN,tr|A0A494BZU9|A0A494BZU9_HUMAN,tr|A0A494C1F2|A0A494C1F2_HUMAN" 4 1501.7652 1.22 20732 21843 3 1501.765098 501.5957 Nuclear pore complex protein Nup214 OS=Homo sapiens OX=9606 GN=NUP214 PE=1 SV=2 4.25 3655.9 - 1.97E+06 - - - -0.0633 - 2.275 0.441 - 197.6 1 2 0 -0.0001 14 0 0 0 1.73E+07 1.42E+07 - - - 5.6411 1 221125_WJC_METTL3_EV_vs_WT_F02.21844.21844.3 6.62E-06 18/52 K.SDIGEVILVGGMTR[166.11].M "sp|P38646|GRP75_HUMAN,tr|H0Y8K0|H0Y8K0_HUMAN,tr|A0A7I2V2S7|A0A7I2V2S7_HUMAN,tr|A0A7I2V2G2|A0A7I2V2G2_HUMAN,tr|A0A7I2V3F7|A0A7I2V3F7_HUMAN,tr|A0A7I2YQB2|A0A7I2YQB2_HUMAN,tr|D6RCD7|D6RCD7_HUMAN" 7 1455.7631 0.34 20733 21844 3 1455.763592 486.2616 "Stress-70 protein, mitochondrial OS=Homo sapiens OX=9606 GN=HSPA9 PE=1 SV=2" 4.37 3656 - 1.69E+06 - - - 0.3483 - 3.227 0.464 - 398.1 1 2 0 0.0005 14 0 0 0 3.38E+07 9.94E+07 - - - 6.8264 0.9995 221125_WJC_METTL3_EV_vs_WT_F02.21850.21850.2 0.000167 14/28 R.VGPDVVTDPAFLVTR.S sp|Q9NV31|IMP3_HUMAN 1 1584.8512 2.7 20738 21850 2 1584.854726 793.4329 U3 small nucleolar ribonucleoprotein protein IMP3 OS=Homo sapiens OX=9606 GN=IMP3 PE=1 SV=1 4.21 3656.7 - 2.61E+06 - - - 2.2513 - 2.204 0.441 - 480.4 1 2 0 0.0036 15 0 0 0 4.33E+07 1.60E+07 - - - 4.24 1 221125_WJC_METTL3_EV_vs_WT_F02.21852.21852.2 0.00293 16/30 R.MIAGQVLDINLAAEPK[136.11].V "sp|P07910|HNRPC_HUMAN,tr|G3V251|G3V251_HUMAN,tr|B4DY08|B4DY08_HUMAN,tr|G3V575|G3V575_HUMAN,tr|B4DSU6|B4DSU6_HUMAN,tr|G3V3K6|G3V3K6_HUMAN,tr|B2R5W2|B2R5W2_HUMAN,tr|G3V4C1|G3V4C1_HUMAN,tr|G3V576|G3V576_HUMAN,tr|G3V5X6|G3V5X6_HUMAN,tr|G3V4W0|G3V4W0_HUMAN,tr|G3V555|G3V555_HUMAN,tr|G3V2Q1|G3V2Q1_HUMAN" 13 1689.9215 1.56 20739 21852 2 1689.91921 845.968 Heterogeneous nuclear ribonucleoproteins C1\C2 OS=Homo sapiens OX=9606 GN=HNRNPC PE=1 SV=4 4.37 3656.9 - 9.07E+07 - - - -1.351 - 3.481 0.578 - 568.8 1 2 0 -0.0023 16 0 0 0 1.64E+09 1.05E+09 - - - 6.376 1 221125_WJC_METTL3_EV_vs_WT_F02.21853.21853.2 1.88E-07 16/26 K.SDIGEVILVGGMTR[166.11].M "sp|P38646|GRP75_HUMAN,tr|H0Y8K0|H0Y8K0_HUMAN,tr|A0A7I2V2S7|A0A7I2V2S7_HUMAN,tr|A0A7I2V2G2|A0A7I2V2G2_HUMAN,tr|A0A7I2V3F7|A0A7I2V3F7_HUMAN,tr|A0A7I2YQB2|A0A7I2YQB2_HUMAN,tr|D6RCD7|D6RCD7_HUMAN" 7 1455.7631 0.38 20740 21853 2 1455.760321 728.8888 "Stress-70 protein, mitochondrial OS=Homo sapiens OX=9606 GN=HSPA9 PE=1 SV=2" 4.37 3657 - 2.82E+07 - - - -1.8987 - 2.951 0.559 - 1110 1 2 0 -0.0028 14 0 0 0 3.41E+08 8.95E+08 - - - 5.8845 0.9999 221125_WJC_METTL3_EV_vs_WT_F02.21854.21854.2 0.0812 13/22 K.DAGVIAGLNVLR[166.11].L "sp|P0DMV8|HS71A_HUMAN,sp|P34931|HS71L_HUMAN,sp|P0DMV9|HS71B_HUMAN,tr|Q53FA3|Q53FA3_HUMAN,tr|A0A0G2JIW1|A0A0G2JIW1_HUMAN" 5 1206.696 0.14 20741 21854 2 1206.695298 604.3553 Heat shock 70 kDa protein 1A OS=Homo sapiens OX=9606 GN=HSPA1A PE=1 SV=1 5.84 3657 - 2.17E+07 - - - -0.5743 - 2.899 0.424 - 627 1 2 0 -0.0007 12 0 0 0 2.80E+09 1.97E+10 - - - 4.973 1 221125_WJC_METTL3_EV_vs_WT_F02.21856.21856.2 8.30E-07 14/28 K.GAEEMETVIPVDVMR.R "sp|Q99497|PARK7_HUMAN,tr|K7ELW0|K7ELW0_HUMAN" 2 1674.7957 2.08 20743 21856 2 1674.793067 838.4051 Parkinson disease protein 7 OS=Homo sapiens OX=9606 GN=PARK7 PE=1 SV=2 4 3657.1 - 4.44E+06 - - - -1.568 - 3.029 0.591 - 537.7 1 2 0 -0.0026 15 0 0 0 2.69E+08 1.29E+08 - - - 6.1299 0.9994 221125_WJC_METTL3_EV_vs_WT_F02.21858.21858.2 1.34E-08 13/26 R.YIQPWESEFIDSQR.V sp|Q6P2Q9|PRP8_HUMAN 1 1796.837 2.35 20745 21858 2 1796.843153 899.4258 Pre-mRNA-processing-splicing factor 8 OS=Homo sapiens OX=9606 GN=PRPF8 PE=1 SV=2 4.14 3657.3 - 2.51E+06 - - - 3.4444 - 2.371 0.568 - 504.3 1 2 0 0.0062 14 0 0 0 2.72E+07 1.16E+07 - - - 5.4007 0.9953 221125_WJC_METTL3_EV_vs_WT_F02.21860.21860.3 0.0816 13/52 K.LLDAVDTYIPVPAR.D sp|P49411|EFTU_HUMAN 1 1541.8453 1.62 20747 21860 3 1541.84064 514.9557 "Elongation factor Tu, mitochondrial OS=Homo sapiens OX=9606 GN=TUFM PE=1 SV=2" 4.21 3657.5 - 2.29E+06 - - - -3.0509 - 1.714 0.287 - 144.7 1 2 0 -0.0047 14 0 0 0 1.46E+07 9.02E+06 - - - 3.1704 1 221125_WJC_METTL3_EV_vs_WT_F02.21862.21862.2 1.43E-10 19/34 R.LLTETEDWLYEEGEDQAK[136.11].Q "sp|Q92598|HS105_HUMAN,tr|A0A0A0MSM0|A0A0A0MSM0_HUMAN" 2 2175.9939 0.001 20749 21862 2 2175.990344 1089.0042 Heat shock protein 105 kDa OS=Homo sapiens OX=9606 GN=HSPH1 PE=1 SV=1 3.71 3657.7 - 1.62E+06 - - - -1.6457 - 3.819 0.708 - 1264.4 1 2 0 -0.0036 18 0 0 0 0.00E+00 4.07E+07 - - - 7.5636 0.9999 221125_WJC_METTL3_EV_vs_WT_F02.21864.21864.3 6.41E-06 16/52 K.SDIGEVILVGGMTR.M "sp|P38646|GRP75_HUMAN,tr|H0Y8K0|H0Y8K0_HUMAN,tr|A0A7I2V2S7|A0A7I2V2S7_HUMAN,tr|A0A7I2V2G2|A0A7I2V2G2_HUMAN,tr|A0A7I2V3F7|A0A7I2V3F7_HUMAN,tr|A0A7I2YQB2|A0A7I2YQB2_HUMAN,tr|D6RCD7|D6RCD7_HUMAN" 7 1445.7548 0.34 20751 21864 3 1445.75113 482.9255 "Stress-70 protein, mitochondrial OS=Homo sapiens OX=9606 GN=HSPA9 PE=1 SV=2" 4.37 3657.9 - 1.56E+06 - - - -2.5488 - 2.772 0.436 - 325.8 1 2 0 -0.0037 14 0 0 0 3.38E+07 9.94E+07 - - - 6.1095 1 221125_WJC_METTL3_EV_vs_WT_F02.21865.21865.2 9.67E-08 14/24 R.YNFPVEVEVPMER.K sp|P78527|PRKDC_HUMAN 1 1607.7654 0.02 20752 21865 2 1607.766992 804.89 DNA-dependent protein kinase catalytic subunit OS=Homo sapiens OX=9606 GN=PRKDC PE=1 SV=3 4.25 3658.1 - 1.12E+06 - - - 1.0033 - 2.492 0.62 - 693.3 1 2 0 0.0016 13 0 0 0 1.09E+07 4.41E+08 - - - 5.9633 0.9999 221125_WJC_METTL3_EV_vs_WT_F02.21866.21866.3 0.000507 Dec-40 K.IMHFPTWVDLK[136.11].G "sp|Q92499|DDX1_HUMAN,tr|A0A7I2V2M5|A0A7I2V2M5_HUMAN,tr|A0A087X2G1|A0A087X2G1_HUMAN,tr|A0A7I2V430|A0A7I2V430_HUMAN,tr|A0A7I2V4F0|A0A7I2V4F0_HUMAN,tr|A0A7I2V4J3|A0A7I2V4J3_HUMAN,tr|A0A087WZ71|A0A087WZ71_HUMAN,tr|A0A7I2YQ77|A0A7I2YQ77_HUMAN" 8 1393.7308 1.3 20753 21866 3 1393.731411 465.5842 ATP-dependent RNA helicase DDX1 OS=Homo sapiens OX=9606 GN=DDX1 PE=1 SV=2 6.74 3658.2 - 1.10E+06 - - - 0.4535 - 2.231 0.386 - 240.7 1 2 0 0.0006 11 0 0 0 2.34E+07 1.81E+07 - - - 5.123 1 221125_WJC_METTL3_EV_vs_WT_F02.21867.21867.2 2.80E-12 21/30 R.WPDFNQEAYVGGTMVR[166.11].S sp|Q10471|GALT2_HUMAN 1 1878.8598 0.97 20754 21867 2 1878.861532 940.4372 Polypeptide N-acetylgalactosaminyltransferase 2 OS=Homo sapiens OX=9606 GN=GALNT2 PE=1 SV=1 4.37 3658.3 - 1.09E+06 - - - 0.9011 - 3.365 0.706 - 1693.4 1 2 0 0.0017 16 0 0 0 2.07E+07 2.13E+07 - - - 7.2383 0.9999 221125_WJC_METTL3_EV_vs_WT_F02.21868.21868.3 1.26E-05 Dec-40 K.IMHFPTWVDLK.G "sp|Q92499|DDX1_HUMAN,tr|A0A7I2V2M5|A0A7I2V2M5_HUMAN,tr|A0A087X2G1|A0A087X2G1_HUMAN,tr|A0A7I2V430|A0A7I2V430_HUMAN,tr|A0A7I2V4F0|A0A7I2V4F0_HUMAN,tr|A0A7I2V4J3|A0A7I2V4J3_HUMAN,tr|A0A087WZ71|A0A087WZ71_HUMAN,tr|A0A7I2YQ77|A0A7I2YQ77_HUMAN" 8 1385.7166 1.27 20755 21868 3 1385.715697 462.9128 ATP-dependent RNA helicase DDX1 OS=Homo sapiens OX=9606 GN=DDX1 PE=1 SV=2 6.74 3658.4 - 904574 - - - -0.6365 - 2.422 0.421 - 256.5 1 2 0 -0.0009 11 0 0 0 2.36E+07 1.87E+07 - - - 5.7465 0.9994 221125_WJC_METTL3_EV_vs_WT_F02.21869.21869.2 0.00786 18-Sep R.DGAYYQLFVR.D "sp|Q9NNW5|WDR6_HUMAN,tr|E9PBK6|E9PBK6_HUMAN,tr|E9PDU5|E9PDU5_HUMAN,tr|A0A087X295|A0A087X295_HUMAN" 4 1230.6033 3.16 20756 21869 2 1230.604364 616.3089 WD repeat-containing protein 6 OS=Homo sapiens OX=9606 GN=WDR6 PE=1 SV=1 5.83 3658.6 - 839050 - - - 0.8459 - 1.81 0.321 - 254.4 1 2 0 0.001 10 0 0 0 4.80E+07 1.52E+07 - - - 3.0677 0.9999 221125_WJC_METTL3_EV_vs_WT_F02.21873.21873.2 5.47E-06 14/22 R.TVQIAAVVDVIR.E sp|P12273|PIP_HUMAN 1 1282.7609 999 20758 21873 2 1282.75979 642.3877 Prolactin-inducible protein OS=Homo sapiens OX=9606 GN=PIP PE=1 SV=1 5.5 3659 - 1.14E+07 - - - -0.8544 - 2.698 0.466 - 832.2 1 2 0 -0.0011 12 0 0 0 8.90E+08 0.00E+00 - - - 5.094 1 221125_WJC_METTL3_EV_vs_WT_F02.21874.21874.3 6.57E-06 Dec-52 K.SFYPEEVSSMVLTK.M "sp|P11142|HSP7C_HUMAN,tr|E9PQQ4|E9PQQ4_HUMAN,tr|E9PKE3|E9PKE3_HUMAN,tr|E9PN89|E9PN89_HUMAN,tr|E9PLF4|E9PLF4_HUMAN,tr|E9PI65|E9PI65_HUMAN,tr|E9PK54|E9PK54_HUMAN,tr|E9PN25|E9PN25_HUMAN,tr|E9PPY6|E9PPY6_HUMAN,tr|E9PQK7|E9PQK7_HUMAN" 10 1615.7804 0.15 20759 21874 3 1615.778648 539.6007 Heat shock cognate 71 kDa protein OS=Homo sapiens OX=9606 GN=HSPA8 PE=1 SV=1 4.53 3659 - 6.38E+06 - - - -1.0602 - 2.161 0.547 - 136.4 1 2 0 -0.0017 14 0 0 0 3.77E+08 2.53E+09 - - - 6.6859 1 221125_WJC_METTL3_EV_vs_WT_F02.21875.21875.2 2.46E-06 14/20 K.DPQFAEDYIFK.A sp|Q9H0D6|XRN2_HUMAN 1 1371.6347 1.09 20760 21875 2 1371.634968 686.8246 5'-3' exoribonuclease 2 OS=Homo sapiens OX=9606 GN=XRN2 PE=1 SV=1 4.03 3659.1 - 5.13E+06 - - - 0.2078 - 2.563 0.605 - 810.2 1 2 0 0.0003 11 0 0 0 5.24E+07 4.80E+07 - - - 6.0556 1 221125_WJC_METTL3_EV_vs_WT_F02.21876.21876.2 4.90E-08 22-Dec K.QYPISLVLAPTR[166.11].E "sp|O00571|DDX3X_HUMAN,sp|O15523|DDX3Y_HUMAN,tr|A0A2R8YFR4|A0A2R8YFR4_HUMAN,tr|A0A2R8YCW1|A0A2R8YCW1_HUMAN,tr|A0A2R8YDH3|A0A2R8YDH3_HUMAN,tr|A0A2R8YDT5|A0A2R8YDT5_HUMAN,tr|A0A2R8Y645|A0A2R8Y645_HUMAN,tr|A0A2R8YF78|A0A2R8YF78_HUMAN,tr|A0A0D9SFB3|A0A0D9SFB3_HUMAN,tr|A0A2R8YFS5|A0A2R8YFS5_HUMAN,tr|A0A0D9SF53|A0A0D9SF53_HUMAN,tr|A0A2R8Y5G6|A0A2R8Y5G6_HUMAN,tr|A0A2R8Y7T2|A0A2R8Y7T2_HUMAN,tr|A0A0D9SG12|A0A0D9SG12_HUMAN,tr|A0A2U3TZJ9|A0A2U3TZJ9_HUMAN,tr|A0A2R8Y4A4|A0A2R8Y4A4_HUMAN" 16 1366.7848 1.22 20761 21876 2 1366.783646 684.3997 ATP-dependent RNA helicase DDX3X OS=Homo sapiens OX=9606 GN=DDX3X PE=1 SV=3 8.75 3659.2 - 5.05E+06 - - - -0.8487 - 2.346 0.613 - 521.3 1 2 0 -0.0012 12 0 0 0 4.57E+08 3.75E+08 - - - 5.8119 0.9999 221125_WJC_METTL3_EV_vs_WT_F02.21877.21877.2 5.13E-09 22-Dec K.QYPISLVLAPTR.E "sp|O00571|DDX3X_HUMAN,sp|O15523|DDX3Y_HUMAN,tr|A0A2R8YFR4|A0A2R8YFR4_HUMAN,tr|A0A2R8YCW1|A0A2R8YCW1_HUMAN,tr|A0A2R8YDH3|A0A2R8YDH3_HUMAN,tr|A0A2R8YDT5|A0A2R8YDT5_HUMAN,tr|A0A2R8Y645|A0A2R8Y645_HUMAN,tr|A0A2R8YF78|A0A2R8YF78_HUMAN,tr|A0A0D9SFB3|A0A0D9SFB3_HUMAN,tr|A0A2R8YFS5|A0A2R8YFS5_HUMAN,tr|A0A0D9SF53|A0A0D9SF53_HUMAN,tr|A0A2R8Y5G6|A0A2R8Y5G6_HUMAN,tr|A0A2R8Y7T2|A0A2R8Y7T2_HUMAN,tr|A0A0D9SG12|A0A0D9SG12_HUMAN,tr|A0A2U3TZJ9|A0A2U3TZJ9_HUMAN,tr|A0A2R8Y4A4|A0A2R8Y4A4_HUMAN" 16 1356.7765 1.22 20762 21877 2 1356.775143 679.3955 ATP-dependent RNA helicase DDX3X OS=Homo sapiens OX=9606 GN=DDX3X PE=1 SV=3 8.75 3659.3 - 4.42E+06 - - - -1.0267 - 2.253 0.583 - 482.7 1 2 0 -0.0014 12 0 0 0 4.57E+08 3.75E+08 - - - 5.4838 0.9997 221125_WJC_METTL3_EV_vs_WT_F02.21879.21879.2 6.10E-06 22-Dec K.GETVPLDVLQIK[136.11].G "sp|Q53H12|AGK_HUMAN,tr|E9PC15|E9PC15_HUMAN,tr|A0A3B3ITV0|A0A3B3ITV0_HUMAN,tr|A0A3B3ITX7|A0A3B3ITX7_HUMAN,tr|E9PG39|E9PG39_HUMAN,tr|A0A3B3ITD0|A0A3B3ITD0_HUMAN,tr|A0A3B3IUC9|A0A3B3IUC9_HUMAN,tr|A0A3B3ISY9|A0A3B3ISY9_HUMAN,tr|A0A3B3ISZ0|A0A3B3ISZ0_HUMAN" 9 1318.7588 1.36 20764 21879 2 1318.75665 660.3867 "Acylglycerol kinase, mitochondrial OS=Homo sapiens OX=9606 GN=AGK PE=1 SV=2" 4.37 3659.4 - 3.50E+06 - - - -1.6061 - 2.144 0.441 - 445.8 1 2 0 -0.0021 12 0 0 0 5.74E+07 4.22E+07 - - - 4.3043 1 221125_WJC_METTL3_EV_vs_WT_F02.21880.21880.3 3.05E-10 22/68 K.VLAPQISFAPEIASEEER.K "sp|P16083|NQO2_HUMAN,tr|Q5TD07|Q5TD07_HUMAN" 2 1985.0106 1.35 20765 21880 3 1985.010565 662.6775 Ribosyldihydronicotinamide dehydrogenase [quinone] OS=Homo sapiens OX=9606 GN=NQO2 PE=1 SV=5 4.09 3659.6 - 3.10E+06 - - - -0.0035 - 3.386 0.558 - 519.8 1 2 0 0 18 0 0 0 1.88E+07 1.38E+07 - - - 7.7982 1 221125_WJC_METTL3_EV_vs_WT_F02.21881.21881.3 5.56E-08 19/44 R.TVQIAAVVDVIR.E sp|P12273|PIP_HUMAN 1 1282.7609 999 20766 21881 3 1282.758425 428.5942 Prolactin-inducible protein OS=Homo sapiens OX=9606 GN=PIP PE=1 SV=1 5.5 3659.7 - 1.79E+06 - - - -1.9185 - 3.208 0.512 - 643.2 1 2 0 -0.0025 12 0 0 0 1.13E+08 0.00E+00 - - - 7.4786 0.9997 221125_WJC_METTL3_EV_vs_WT_F02.21882.21882.3 0.0361 13/52 K.LLDAVDTYIPVPAR[166.11].D sp|P49411|EFTU_HUMAN 1 1551.8536 1.62 20767 21882 3 1551.853371 518.2918 "Elongation factor Tu, mitochondrial OS=Homo sapiens OX=9606 GN=TUFM PE=1 SV=2" 4.21 3659.8 - 1.40E+06 - - - -0.1566 - 2.072 0.342 - 178.8 1 2 0 -0.0002 14 0 0 0 1.46E+07 9.02E+06 - - - 4.2889 0.9914 221125_WJC_METTL3_EV_vs_WT_F02.21884.21884.2 0.000174 13/22 K.NLQEEIDALESR[166.11].V "sp|Q9NQP4|PFD4_HUMAN,tr|E9PQY2|E9PQY2_HUMAN" 2 1425.6975 0.05 20769 21884 2 1426.700131 713.856 Prefoldin subunit 4 OS=Homo sapiens OX=9606 GN=PFDN4 PE=1 SV=1 4 3660.1 - 934271 - - - 703.2509 - 2.493 0.396 - 610.2 1 2 0 1.0026 12 0 0 0 1.17E+06 2.33E+07 - - - 4.0546 1 221125_WJC_METTL3_EV_vs_WT_F02.21887.21887.3 7.97E-08 16/44 K.DAGVIAGLNVLR[166.11].L "sp|P0DMV8|HS71A_HUMAN,sp|P34931|HS71L_HUMAN,sp|P0DMV9|HS71B_HUMAN,tr|Q53FA3|Q53FA3_HUMAN,tr|A0A0G2JIW1|A0A0G2JIW1_HUMAN" 5 1206.696 0.14 20770 21887 3 1206.693898 403.2393 Heat shock 70 kDa protein 1A OS=Homo sapiens OX=9606 GN=HSPA1A PE=1 SV=1 5.84 3660.4 - 1.38E+07 - - - -1.7345 - 2.799 0.527 - 387.4 1 2 0 -0.0021 12 0 0 0 6.93E+07 4.81E+08 - - - 7.2679 1 221125_WJC_METTL3_EV_vs_WT_F02.21888.21888.3 2.86E-08 15/68 R.LLTETEDWLYEEGEDQAK[136.11].Q "sp|Q92598|HS105_HUMAN,tr|A0A0A0MSM0|A0A0A0MSM0_HUMAN" 2 2175.9939 0.08 20771 21888 3 2175.993336 726.3386 Heat shock protein 105 kDa OS=Homo sapiens OX=9606 GN=HSPH1 PE=1 SV=1 3.71 3660.5 - 9.82E+06 - - - -0.2707 - 2.574 0.611 - 324.2 1 2 0 -0.0006 18 0 0 0 8.02E+06 1.06E+08 - - - 7.7062 0.9998 221125_WJC_METTL3_EV_vs_WT_F02.21889.21889.2 0.00914 14/22 K.DAGVIAGLNVLR.L "sp|P0DMV8|HS71A_HUMAN,sp|P34931|HS71L_HUMAN,sp|P0DMV9|HS71B_HUMAN,tr|Q53FA3|Q53FA3_HUMAN,tr|A0A0G2JIW1|A0A0G2JIW1_HUMAN" 5 1196.6877 0.14 20772 21889 2 1196.686978 599.3511 Heat shock 70 kDa protein 1A OS=Homo sapiens OX=9606 GN=HSPA1A PE=1 SV=1 5.84 3660.5 - 6.56E+07 - - - -0.6209 - 2.669 0.384 - 761.5 1 2 0 -0.0007 12 0 0 0 2.80E+09 1.97E+10 - - - 4.46 0.991 221125_WJC_METTL3_EV_vs_WT_F02.21890.21890.3 0.00252 17/68 K.LLHHLSDLALTLPTDAVS.L "sp|Q86U44|MTA70_HUMAN,tr|B4E349|B4E349_HUMAN,tr|F5H6D8|F5H6D8_HUMAN,tr|H0YFV6|H0YFV6_HUMAN,tr|B4DTN4|B4DTN4_HUMAN" 5 1915.0415 - 20773 21890 3 1915.041112 639.3544 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 5.05 3660.6 - 9.35E+06 - - - -0.1911 - 2.867 0.374 - 314.5 1 1 0 -0.0004 18 0 0 0 - - - - - 5.3324 0.9999 221125_WJC_METTL3_EV_vs_WT_F02.21893.21893.3 1.46E-05 13/56 K.GAEEMETVIPVDVMR.R "sp|Q99497|PARK7_HUMAN,tr|K7ELW0|K7ELW0_HUMAN" 2 1674.7957 2.16 20776 21893 3 1674.793817 559.2725 Parkinson disease protein 7 OS=Homo sapiens OX=9606 GN=PARK7 PE=1 SV=2 4 3660.7 - 5.26E+06 - - - -1.1201 - 2.308 0.468 - 184.1 1 2 0 -0.0019 15 0 0 0 7.43E+07 3.44E+07 - - - 5.9396 1 221125_WJC_METTL3_EV_vs_WT_F02.21894.21894.2 0.000145 23/36 K.LLGPDAAINLTDPDGALAK.R "sp|Q13561|DCTN2_HUMAN,tr|H0YI98|H0YI98_HUMAN,tr|A8K8J9|A8K8J9_HUMAN,tr|F8W1I6|F8W1I6_HUMAN,tr|A0A7I2V4H4|A0A7I2V4H4_HUMAN,tr|A0A7I2V390|A0A7I2V390_HUMAN,tr|A0A7I2V4Y9|A0A7I2V4Y9_HUMAN,tr|F8VW18|F8VW18_HUMAN" 8 1863.9942 4.34 20777 21894 2 1863.991574 933.0044 Dynactin subunit 2 OS=Homo sapiens OX=9606 GN=DCTN2 PE=1 SV=4 3.93 3660.8 - 5.09E+06 - - - -1.405 - 3.937 0.597 - 1252.9 1 2 0 -0.0026 19 0 0 0 2.26E+08 5.20E+07 - - - 6.8189 1 221125_WJC_METTL3_EV_vs_WT_F02.21895.21895.2 2.27E-07 17/30 R.WPDFNQEAYVGGTMVR.S sp|Q10471|GALT2_HUMAN 1 1868.8516 0.97 20778 21895 2 1868.841311 935.4331 Polypeptide N-acetylgalactosaminyltransferase 2 OS=Homo sapiens OX=9606 GN=GALNT2 PE=1 SV=1 4.37 3660.8 - 4.68E+06 - - - -5.4889 - 3.113 0.674 - 1046.6 1 2 0 -0.0103 16 0 0 0 2.07E+07 2.13E+07 - - - 6.8078 1 221125_WJC_METTL3_EV_vs_WT_F02.21896.21896.3 7.12E-08 16/52 K.FFVTLLEAQADYHR[166.11].K sp|Q68EM7|RHG17_HUMAN 1 1718.8656 1.23 20779 21896 3 1718.864834 573.9625 Rho GTPase-activating protein 17 OS=Homo sapiens OX=9606 GN=ARHGAP17 PE=1 SV=1 5.32 3660.9 - 2.76E+06 - - - -0.4317 - 3.018 0.49 - 214.4 1 2 0 -0.0007 14 0 0 0 3.35E+07 2.72E+07 - - - 6.9383 1 221125_WJC_METTL3_EV_vs_WT_F02.21902.21902.3 8.72E-07 17/72 K.LLGPDAAINLTDPDGALAK.R "sp|Q13561|DCTN2_HUMAN,tr|H0YI98|H0YI98_HUMAN,tr|A8K8J9|A8K8J9_HUMAN,tr|F8W1I6|F8W1I6_HUMAN,tr|A0A7I2V4H4|A0A7I2V4H4_HUMAN,tr|A0A7I2V390|A0A7I2V390_HUMAN,tr|A0A7I2V4Y9|A0A7I2V4Y9_HUMAN,tr|F8VW18|F8VW18_HUMAN" 8 1863.9942 5.88 20783 21902 3 1863.990879 622.3387 Dynactin subunit 2 OS=Homo sapiens OX=9606 GN=DCTN2 PE=1 SV=4 3.93 3661.7 - 4.39E+06 - - - -1.7779 - 3.042 0.487 - 288.1 1 2 0 -0.0033 19 0 0 0 6.78E+07 1.15E+07 - - - 6.7019 1 221125_WJC_METTL3_EV_vs_WT_F02.21904.21904.3 7.23E-08 15/44 K.DAGVIAGLNVLR.L "sp|P0DMV8|HS71A_HUMAN,sp|P34931|HS71L_HUMAN,sp|P0DMV9|HS71B_HUMAN,tr|Q53FA3|Q53FA3_HUMAN,tr|A0A0G2JIW1|A0A0G2JIW1_HUMAN" 5 1196.6877 0.14 20785 21904 3 1196.685971 399.9032 Heat shock 70 kDa protein 1A OS=Homo sapiens OX=9606 GN=HSPA1A PE=1 SV=1 5.84 3661.9 - 2.75E+06 - - - -1.4624 - 3.012 0.515 - 289.4 1 2 0 -0.0018 12 0 0 0 6.93E+07 4.81E+08 - - - 7.3375 0.9999 221125_WJC_METTL3_EV_vs_WT_F02.21906.21906.3 2.44E-05 13/44 R.LDILHQVAMWQK[136.11].N "sp|Q9BYD3|RM04_HUMAN,tr|X6RAY8|X6RAY8_HUMAN,tr|K7ES61|K7ES61_HUMAN,tr|K7ELF1|K7ELF1_HUMAN,tr|K7ELQ0|K7ELQ0_HUMAN,tr|K7EKI4|K7EKI4_HUMAN" 6 1488.8003 1.12 20787 21906 3 1488.796887 497.274 "39S ribosomal protein L4, mitochondrial OS=Homo sapiens OX=9606 GN=MRPL4 PE=1 SV=1" 6.74 3662.2 - 1.87E+06 - - - -2.2622 - 2.809 0.413 - 266.2 1 2 0 -0.0034 12 0 0 0 2.12E+07 1.90E+07 - - - 6.0065 1 221125_WJC_METTL3_EV_vs_WT_F02.21910.21910.2 9.82E-10 16/26 K.SDIGEVILVGGMTR.M "sp|P38646|GRP75_HUMAN,tr|H0Y8K0|H0Y8K0_HUMAN,tr|A0A7I2V2S7|A0A7I2V2S7_HUMAN,tr|A0A7I2V2G2|A0A7I2V2G2_HUMAN,tr|A0A7I2V3F7|A0A7I2V3F7_HUMAN,tr|A0A7I2YQB2|A0A7I2YQB2_HUMAN,tr|D6RCD7|D6RCD7_HUMAN" 7 1445.7548 0.38 20790 21910 2 1445.753112 723.8847 "Stress-70 protein, mitochondrial OS=Homo sapiens OX=9606 GN=HSPA9 PE=1 SV=2" 4.37 3662.7 - 1.85E+07 - - - -1.1779 - 3.029 0.591 - 1068.8 1 2 0 -0.0017 14 0 0 0 3.41E+08 8.95E+08 - - - 6.1866 1 221125_WJC_METTL3_EV_vs_WT_F02.21912.21912.3 0.000114 15/48 R.K[136.11]AIIIFVPVPQLK[136.11].S "sp|P62081|RS7_HUMAN,tr|B5MCP9|B5MCP9_HUMAN" 2 1480.9716 0.74 20791 21912 3 1480.968792 494.6645 40S ribosomal protein S7 OS=Homo sapiens OX=9606 GN=RPS7 PE=1 SV=1 10 3662.9 - 5.37E+06 - - - -1.9015 - 2.212 0.568 - 281.8 1 2 0 -0.0028 13 0 0 0 9.71E+07 1.31E+08 - - - 7.0243 1 221125_WJC_METTL3_EV_vs_WT_F02.21914.21914.2 1.51E-07 14/22 K.YGLEGTVFFEEK.D "sp|Q9Y2L1|RRP44_HUMAN,tr|G3V1J5|G3V1J5_HUMAN" 2 1417.6765 1.56 20793 21914 2 1417.675546 709.8456 Exosome complex exonuclease RRP44 OS=Homo sapiens OX=9606 GN=DIS3 PE=1 SV=2 4.25 3663.1 - 2.90E+06 - - - -0.7068 - 2.725 0.603 - 641.1 1 2 0 -0.001 12 0 0 0 4.51E+07 2.90E+07 - - - 6.1321 1 221125_WJC_METTL3_EV_vs_WT_F02.21915.21915.3 9.85E-08 16/48 R.KAIIIFVPVPQLK.S "sp|P62081|RS7_HUMAN,tr|B5MCP9|B5MCP9_HUMAN" 2 1464.9432 0.74 20794 21915 3 1464.941522 489.3217 40S ribosomal protein S7 OS=Homo sapiens OX=9606 GN=RPS7 PE=1 SV=1 10 3663.2 - 2.86E+06 - - - -1.1509 - 2.657 0.582 - 347.8 1 2 0 -0.0017 13 0 0 0 9.67E+07 1.31E+08 - - - 7.6777 1 221125_WJC_METTL3_EV_vs_WT_F02.21916.21916.2 2.81E-10 14/26 R.VNFDDYTVNLGGLK.D "sp|Q06210|GFPT1_HUMAN,tr|A0A6I8PRN4|A0A6I8PRN4_HUMAN,tr|A0A6I8PTT9|A0A6I8PTT9_HUMAN" 3 1553.7726 0.95 20795 21916 2 1553.769341 777.8936 Glutamine--fructose-6-phosphate aminotransferase [isomerizing] 1 OS=Homo sapiens OX=9606 GN=GFPT1 PE=1 SV=3 4.21 3663.4 - 2.19E+06 - - - -2.0801 - 2.724 0.601 - 701.6 1 2 0 -0.0032 14 0 0 0 3.72E+07 3.89E+07 - - - 5.9937 0.9618 221125_WJC_METTL3_EV_vs_WT_F02.21917.21917.2 0.00111 15/26 R.VETGVLK[136.11]PGMVVTF.A "sp|P68104|EF1A1_HUMAN,sp|Q5VTE0|EF1A3_HUMAN,tr|A0A7I2V659|A0A7I2V659_HUMAN,tr|A0A7I2V3H3|A0A7I2V3H3_HUMAN,tr|A0A7I2V5N4|A0A7I2V5N4_HUMAN,tr|A0A087WVQ9|A0A087WVQ9_HUMAN" 6 1483.82 0.29 20796 21917 2 1483.817556 742.9173 Elongation factor 1-alpha 1 OS=Homo sapiens OX=9606 GN=EEF1A1 PE=1 SV=1 5.97 3663.5 - 2.12E+06 - - - -1.639 - 1.974 0.343 - 184.8 1 1 0 -0.0024 14 0 0 0 9.78E+06 3.41E+07 - - - 3.2802 0.8281 221125_WJC_METTL3_EV_vs_WT_F02.21921.21921.2 1.34E-05 13/24 R.VNQAIWLLC[160.03]TGAR[166.11].E "sp|P46782|RS5_HUMAN,tr|M0QZN2|M0QZN2_HUMAN,tr|M0R0F0|M0R0F0_HUMAN,tr|M0R0R2|M0R0R2_HUMAN" 4 1510.7954 0.58 20798 21921 2 1512.798584 756.405 40S ribosomal protein S5 OS=Homo sapiens OX=9606 GN=RPS5 PE=1 SV=4 8.22 3664 - 3.63E+06 - - - 1325.9214 - 2.103 0.509 - 353.6 1 2 0 2.0032 13 0 0 0 2.19E+08 3.80E+08 - - - 4.0793 0.9944 221125_WJC_METTL3_EV_vs_WT_F02.21922.21922.2 2.02E-08 26-Oct R.VNFDDYTVNLGGLK[136.11].D "sp|Q06210|GFPT1_HUMAN,tr|A0A6I8PRN4|A0A6I8PRN4_HUMAN,tr|A0A6I8PTT9|A0A6I8PTT9_HUMAN" 3 1561.7868 0.87 20799 21922 2 1561.779355 781.9007 Glutamine--fructose-6-phosphate aminotransferase [isomerizing] 1 OS=Homo sapiens OX=9606 GN=GFPT1 PE=1 SV=3 4.21 3664.1 - 3.43E+06 - - - -4.7497 - 2.237 0.317 - 286.9 1 2 0 -0.0074 14 0 0 0 3.29E+07 3.77E+07 - - - 3.4005 0.9999 221125_WJC_METTL3_EV_vs_WT_F02.21924.21924.2 0.00059 13/26 R.YNVLGAETVLNQMR.M "sp|Q1KMD3|HNRL2_HUMAN,tr|H3BQZ7|H3BQZ7_HUMAN" 2 1606.8137 999 20801 21924 2 1606.811252 804.4141 Heterogeneous nuclear ribonucleoprotein U-like protein 2 OS=Homo sapiens OX=9606 GN=HNRNPUL2 PE=1 SV=1 6 3664.3 - 3.82E+06 - - - -1.5403 - 2.579 0.544 - 373.4 1 2 0 -0.0025 14 0 0 0 1.10E+08 0.00E+00 - - - 5.4357 1 221125_WJC_METTL3_EV_vs_WT_F02.21926.21926.3 1.43E-08 15/64 K.LLLDMGSDINAQIETNR.N "sp|O75179|ANR17_HUMAN,sp|Q8IWZ3|ANKH1_HUMAN,tr|E9PDP5|E9PDP5_HUMAN,tr|H0YM23|H0YM23_HUMAN,tr|H3BLS9|H3BLS9_HUMAN,tr|H0YLQ3|H0YLQ3_HUMAN,tr|H7C2F5|H7C2F5_HUMAN" 7 1901.9517 1.93 20803 21926 3 1901.94857 634.9912 Ankyrin repeat domain-containing protein 17 OS=Homo sapiens OX=9606 GN=ANKRD17 PE=1 SV=3 4.03 3664.5 - 1.60E+06 - - - -1.6336 - 3.017 0.531 - 291.3 1 2 0 -0.0031 17 0 0 0 2.74E+07 1.42E+07 - - - 7.249 0.9915 221125_WJC_METTL3_EV_vs_WT_F02.21931.21931.2 4.28E-07 14/26 L.GIETAGGVMTVLIK[136.11].R "sp|P11142|HSP7C_HUMAN,tr|E9PNE6|E9PNE6_HUMAN,tr|A8K7Q2|A8K7Q2_HUMAN,tr|E9PKE3|E9PKE3_HUMAN" 4 1395.7887 0.11 20806 21931 2 1395.786356 698.9016 Heat shock cognate 71 kDa protein OS=Homo sapiens OX=9606 GN=HSPA8 PE=1 SV=1 6 3665.1 - 2.20E+06 - - - -1.67 - 3.003 0.526 - 382 1 1 0 -0.0023 14 0 0 0 5.42E+06 4.76E+07 - - - 5.6847 1 221125_WJC_METTL3_EV_vs_WT_F02.21932.21932.2 4.28E-11 22/36 K.LLGPDAAINLTDPDGALAK[136.11].R "sp|Q13561|DCTN2_HUMAN,tr|H0YI98|H0YI98_HUMAN,tr|A8K8J9|A8K8J9_HUMAN,tr|F8W1I6|F8W1I6_HUMAN,tr|A0A7I2V4H4|A0A7I2V4H4_HUMAN,tr|A0A7I2V390|A0A7I2V390_HUMAN,tr|A0A7I2V4Y9|A0A7I2V4Y9_HUMAN,tr|F8VW18|F8VW18_HUMAN" 8 1872.0084 4.33 20807 21932 2 1872.010148 937.0115 Dynactin subunit 2 OS=Homo sapiens OX=9606 GN=DCTN2 PE=1 SV=4 3.93 3665.2 - 3.12E+06 - - - 0.9375 - 3.508 0.64 - 1098 1 2 0 0.0018 19 0 0 0 2.25E+08 5.20E+07 - - - 6.8531 0.9999 221125_WJC_METTL3_EV_vs_WT_F02.21938.21938.2 3.62E-05 13/22 R.TVVSGLVQFVPK.E "sp|P54577|SYYC_HUMAN,tr|A0A6Q8PFX2|A0A6Q8PFX2_HUMAN" 2 1272.7442 0.08 20811 21938 2 1272.745134 637.3794 "Tyrosine--tRNA ligase, cytoplasmic OS=Homo sapiens OX=9606 GN=YARS1 PE=1 SV=4" 8.41 3666 - 3.50E+06 - - - 0.7543 - 2.372 0.49 - 351.1 1 2 0 0.001 12 0 0 0 6.12E+07 8.03E+08 - - - 4.9325 1 221125_WJC_METTL3_EV_vs_WT_F02.21939.21939.3 5.46E-07 23/76 R.LALVTGGEIASTFDHPELVK[136.11].L "sp|P78371|TCPB_HUMAN,tr|F8VQ14|F8VQ14_HUMAN,tr|F5GWF6|F5GWF6_HUMAN" 3 2104.1296 0.53 20812 21939 3 2104.13044 702.3838 T-complex protein 1 subunit beta OS=Homo sapiens OX=9606 GN=CCT2 PE=1 SV=4 4.65 3666.1 - 3.37E+06 - - - 0.413 - 3.708 0.545 - 528.5 1 2 0 0.0009 20 0 0 0 4.43E+08 8.32E+08 - - - 7.7953 0.9999 221125_WJC_METTL3_EV_vs_WT_F02.21943.21943.3 2.60E-05 Dec-48 R.VNQAIWLLC[160.03]TGAR[166.11].E "sp|P46782|RS5_HUMAN,tr|M0QZN2|M0QZN2_HUMAN,tr|M0R0F0|M0R0F0_HUMAN,tr|M0R0R2|M0R0R2_HUMAN" 4 1510.7954 0.92 20814 21943 3 1510.793537 504.6057 40S ribosomal protein S5 OS=Homo sapiens OX=9606 GN=RPS5 PE=1 SV=4 8.22 3666.6 - 3.79E+06 - - - -1.2252 - 2.632 0.391 - 223.9 1 2 0 -0.0019 13 0 0 0 5.48E+07 5.94E+07 - - - 5.5226 1 221125_WJC_METTL3_EV_vs_WT_F02.21944.21944.2 1.17E-06 19/30 R.AYLESEVAISEELVQK.Y "sp|Q9NQC3|RTN4_HUMAN,tr|A0A0U1RQR6|A0A0U1RQR6_HUMAN,tr|F8W914|F8W914_HUMAN,tr|H7C106|H7C106_HUMAN" 4 1806.9251 1.72 20815 21944 2 1806.928698 904.4698 Reticulon-4 OS=Homo sapiens OX=9606 GN=RTN4 PE=1 SV=2 4.09 3666.7 - 2.11E+06 - - - 1.9851 - 3.832 0.572 - 1167.9 1 2 0 0.0036 16 0 0 0 3.18E+07 1.85E+07 - - - 6.5674 1 221125_WJC_METTL3_EV_vs_WT_F02.21945.21945.2 5.92E-09 14/24 R.PSENLGQVLFGER.L sp|Q99805|TM9S2_HUMAN 1 1444.731 1.24 20816 21945 2 1444.728559 723.3728 Transmembrane 9 superfamily member 2 OS=Homo sapiens OX=9606 GN=TM9SF2 PE=1 SV=1 4.53 3666.8 - 4.85E+06 - - - -1.7194 - 3.181 0.612 - 662.3 1 1 0 -0.0025 13 0 0 0 4.81E+07 3.87E+07 - - - 6.5304 1 221125_WJC_METTL3_EV_vs_WT_F02.21946.21946.3 3.01E-05 16/48 R.VNQAIWLLC[160.03]TGAR.E "sp|P46782|RS5_HUMAN,tr|M0QZN2|M0QZN2_HUMAN,tr|M0R0F0|M0R0F0_HUMAN,tr|M0R0R2|M0R0R2_HUMAN" 4 1500.7871 0.92 20817 21946 3 1500.785139 501.2696 40S ribosomal protein S5 OS=Homo sapiens OX=9606 GN=RPS5 PE=1 SV=4 8.22 3666.9 - 3.66E+06 - - - -1.3186 - 2.817 0.477 - 313 1 2 0 -0.002 13 0 0 0 5.48E+07 5.94E+07 - - - 6.6655 0.9999 221125_WJC_METTL3_EV_vs_WT_F02.21949.21949.2 2.29E-07 15/24 R.AQEIDGQALLLLK.E "sp|Q8IXK0|PHC2_HUMAN,sp|Q8NDX5|PHC3_HUMAN,tr|H7C528|H7C528_HUMAN,tr|A0A0A0MSI2|A0A0A0MSI2_HUMAN,tr|B3KPJ4|B3KPJ4_HUMAN" 5 1410.8082 1.96 20820 21949 2 1410.808927 706.4114 Polyhomeotic-like protein 2 OS=Homo sapiens OX=9606 GN=PHC2 PE=1 SV=1 4.37 3667.2 - 2.09E+06 - - - 0.494 - 2.791 0.485 - 711 1 2 0 0.0007 13 0 0 0 6.17E+07 3.14E+07 - - - 5.2573 0.9998 221125_WJC_METTL3_EV_vs_WT_F02.21950.21950.3 0.00365 Oct-52 R.YNVLGAETVLNQMR.M "sp|Q1KMD3|HNRL2_HUMAN,tr|H3BQZ7|H3BQZ7_HUMAN" 2 1606.8137 999 20821 21950 3 1606.813263 536.6119 Heterogeneous nuclear ribonucleoprotein U-like protein 2 OS=Homo sapiens OX=9606 GN=HNRNPUL2 PE=1 SV=1 6 3667.3 - 1.79E+06 - - - -0.2888 - 1.897 0.373 - 109.8 1 2 0 -0.0005 14 0 0 0 1.81E+07 0.00E+00 - - - 4.4 0.9998 221125_WJC_METTL3_EV_vs_WT_F02.21951.21951.3 0.00686 Nov-44 K.QYPISLVLAPTR.E "sp|O00571|DDX3X_HUMAN,sp|O15523|DDX3Y_HUMAN,tr|A0A2R8YFR4|A0A2R8YFR4_HUMAN,tr|A0A2R8YCW1|A0A2R8YCW1_HUMAN,tr|A0A2R8YDH3|A0A2R8YDH3_HUMAN,tr|A0A2R8YDT5|A0A2R8YDT5_HUMAN,tr|A0A2R8Y645|A0A2R8Y645_HUMAN,tr|A0A2R8YF78|A0A2R8YF78_HUMAN,tr|A0A0D9SFB3|A0A0D9SFB3_HUMAN,tr|A0A2R8YFS5|A0A2R8YFS5_HUMAN,tr|A0A0D9SF53|A0A0D9SF53_HUMAN,tr|A0A2R8Y5G6|A0A2R8Y5G6_HUMAN,tr|A0A2R8Y7T2|A0A2R8Y7T2_HUMAN,tr|A0A0D9SG12|A0A0D9SG12_HUMAN,tr|A0A2U3TZJ9|A0A2U3TZJ9_HUMAN,tr|A0A2R8Y4A4|A0A2R8Y4A4_HUMAN" 16 1356.7765 1.49 20822 21951 3 1356.775288 453.2661 ATP-dependent RNA helicase DDX3X OS=Homo sapiens OX=9606 GN=DDX3X PE=1 SV=3 8.75 3667.4 - 921115 - - - -0.9198 - 2.011 0.353 - 191.7 1 2 0 -0.0012 12 0 0 0 1.09E+07 7.30E+06 - - - 4.4118 0.9985 221125_WJC_METTL3_EV_vs_WT_F02.21953.21953.2 0.168 16-Jul R.MWFQWSEQR[166.11].D "sp|O15260|SURF4_HUMAN,tr|B7Z1G8|B7Z1G8_HUMAN,tr|Q5T8U5|Q5T8U5_HUMAN" 3 1306.5792 0.8 20824 21953 2 1306.57822 654.2969 Surfeit locus protein 4 OS=Homo sapiens OX=9606 GN=SURF4 PE=1 SV=3 5.75 3667.7 - 737009 - - - -0.786 - 1.33 0.304 - 109.5 1 2 0 -0.001 9 0 0 0 3.17E+06 3.95E+06 - - - 2.1111 1 221125_WJC_METTL3_EV_vs_WT_F02.21956.21956.3 6.00E-09 19/76 R.LALVTGGEIASTFDHPELVK.L "sp|P78371|TCPB_HUMAN,tr|F8VQ14|F8VQ14_HUMAN,tr|F5GWF6|F5GWF6_HUMAN" 3 2096.1154 0.53 20825 21956 3 2096.114998 699.7124 T-complex protein 1 subunit beta OS=Homo sapiens OX=9606 GN=CCT2 PE=1 SV=4 4.65 3668.1 - 2.82E+07 - - - -0.1779 - 3.476 0.594 - 374 1 2 0 -0.0004 20 0 0 0 4.43E+08 8.32E+08 - - - 8.1849 1 221125_WJC_METTL3_EV_vs_WT_F02.21957.21957.2 1.56E-08 17/28 K.NFINNPLAQADWAAK.K "sp|P35579|MYH9_HUMAN,tr|Q5BKV1|Q5BKV1_HUMAN,tr|B1AH99|B1AH99_HUMAN" 3 1671.8369 1.19 20826 21957 2 1671.833175 836.9257 Myosin-9 OS=Homo sapiens OX=9606 GN=MYH9 PE=1 SV=4 5.84 3668.1 - 3.47E+06 - - - -2.2311 - 3.25 0.641 - 994.6 1 2 0 -0.0037 15 0 0 0 9.35E+07 7.84E+07 - - - 6.672 0.9991 221125_WJC_METTL3_EV_vs_WT_F02.21958.21958.3 1.13E-06 18/88 R.AVLIDEVC[160.03]TMNDGPHSALYTMMK.D "sp|Q14671|PUM1_HUMAN,tr|Q5T1Z8|Q5T1Z8_HUMAN,tr|H0YDK8|H0YDK8_HUMAN,tr|H0YEH2|H0YEH2_HUMAN,tr|Q5T1Z4|Q5T1Z4_HUMAN,tr|E9PR38|E9PR38_HUMAN" 6 2595.1841 3.41 20827 21958 3 2595.185096 866.0687 Pumilio homolog 1 OS=Homo sapiens OX=9606 GN=PUM1 PE=1 SV=3 4.54 3668.2 - 5.12E+06 - - - 0.3691 - 2.388 0.252 - 89.5 1 2 0 0.001 23 0 0 0 5.63E+07 1.65E+07 - - - 3.3913 1 221125_WJC_METTL3_EV_vs_WT_F02.21959.21959.2 1.21E-08 28-Dec K.NFINNPLAQADWAAK[136.11].K "sp|P35579|MYH9_HUMAN,tr|Q5BKV1|Q5BKV1_HUMAN,tr|B1AH99|B1AH99_HUMAN" 3 1679.8511 1.19 20828 21959 2 1679.84707 840.9328 Myosin-9 OS=Homo sapiens OX=9606 GN=MYH9 PE=1 SV=4 5.84 3668.3 - 3.65E+06 - - - -2.402 - 2.683 0.605 - 348.6 1 2 0 -0.004 15 0 0 0 9.35E+07 7.84E+07 - - - 5.9347 1 221125_WJC_METTL3_EV_vs_WT_F02.21960.21960.2 4.00E-09 15/24 R.PSENLGQVLFGER[166.11].L sp|Q99805|TM9S2_HUMAN 1 1454.7393 1.24 20829 21960 2 1454.736426 728.3769 Transmembrane 9 superfamily member 2 OS=Homo sapiens OX=9606 GN=TM9SF2 PE=1 SV=1 4.53 3668.4 - 2.78E+06 - - - -1.9845 - 3.26 0.563 - 807.4 1 1 0 -0.0029 13 0 0 0 4.81E+07 3.87E+07 - - - 6.2313 1 221125_WJC_METTL3_EV_vs_WT_F02.21962.21962.2 5.67E-08 24-Dec R.AQEIDGQALLLLK[136.11].E "sp|Q8IXK0|PHC2_HUMAN,sp|Q8NDX5|PHC3_HUMAN,tr|H7C528|H7C528_HUMAN,tr|A0A0A0MSI2|A0A0A0MSI2_HUMAN,tr|B3KPJ4|B3KPJ4_HUMAN" 5 1418.8224 1.96 20831 21962 2 1418.826898 710.4185 Polyhomeotic-like protein 2 OS=Homo sapiens OX=9606 GN=PHC2 PE=1 SV=1 4.37 3668.5 - 2.54E+06 - - - 3.1491 - 2.588 0.606 - 443.6 1 2 0 0.0045 13 0 0 0 6.17E+07 3.14E+07 - - - 5.956 0.9994 221125_WJC_METTL3_EV_vs_WT_F02.21963.21963.4 1.41E-05 24/114 R.LALVTGGEIASTFDHPELVK[136.11].L "sp|P78371|TCPB_HUMAN,tr|F8VQ14|F8VQ14_HUMAN,tr|F5GWF6|F5GWF6_HUMAN" 3 2104.1296 0.56 20832 21963 4 2104.120486 527.0397 T-complex protein 1 subunit beta OS=Homo sapiens OX=9606 GN=CCT2 PE=1 SV=4 4.65 3668.6 - 2.42E+06 - - - -4.3177 - 3.389 0.435 - 350.8 1 2 0 -0.0091 20 0 0 0 1.33E+07 2.38E+07 - - - 3.4178 1 221125_WJC_METTL3_EV_vs_WT_F02.21964.21964.3 4.72E-05 21/52 R.EAVELPLTHFELYK[136.11].Q sp|P43686|PRS6B_HUMAN 1 1695.8963 0.67 20833 21964 3 1695.897555 566.3061 26S proteasome regulatory subunit 6B OS=Homo sapiens OX=9606 GN=PSMC4 PE=1 SV=2 4.75 3668.7 - 1.39E+06 - - - 0.7259 - 3.161 0.43 - 553.1 1 2 0 0.0012 14 0 0 0 1.23E+07 1.83E+07 - - - 6.3923 1 221125_WJC_METTL3_EV_vs_WT_F02.21965.21965.2 4.02E-10 16/30 K.VLTLVSQIDVNNEFEK.L sp|Q92621|NU205_HUMAN 1 1846.9676 1.77 20834 21965 2 1846.971855 924.4911 Nuclear pore complex protein Nup205 OS=Homo sapiens OX=9606 GN=NUP205 PE=1 SV=3 4.14 3668.8 - 1.34E+06 - - - 2.28 - 3.52 0.622 - 816.5 1 2 0 0.0042 16 0 0 0 1.14E+07 6.48E+06 - - - 6.7278 1 221125_WJC_METTL3_EV_vs_WT_F02.21966.21966.2 2.68E-06 14/32 R.HIADLAGNSEVILPVPA.F "sp|P06733|ENOA_HUMAN,tr|A0A2R8Y6G6|A0A2R8Y6G6_HUMAN,tr|K7EM90|K7EM90_HUMAN,tr|A0A2R8YEM5|A0A2R8YEM5_HUMAN" 4 1714.9254 - 20835 21966 2 1714.93061 858.47 Alpha-enolase OS=Homo sapiens OX=9606 GN=ENO1 PE=1 SV=2 4.35 3669 - 1.13E+06 - - - 3.0462 - 2.789 0.568 - 290 1 1 0 0.0052 17 0 0 0 - - - - - 5.7563 0.9999 221125_WJC_METTL3_EV_vs_WT_F02.21968.21968.2 7.70E-06 16/30 R.AGAASLDVIQEVEYVK[136.11].E sp|Q9UJV9|DDX41_HUMAN 1 1698.892 -1 20837 21968 2 1698.889984 850.4533 Probable ATP-dependent RNA helicase DDX41 OS=Homo sapiens OX=9606 GN=DDX41 PE=1 SV=2 4.14 3669.2 - 859068 - - - -1.1672 - 2.893 0.484 - 841.1 1 2 0 -0.002 16 0 0 0 0.00E+00 0.00E+00 - - - 5.2269 1 221125_WJC_METTL3_EV_vs_WT_F02.21971.21971.3 3.48E-11 26/84 K.FVDGLMIHSGDPVNYYVDTAVR[166.11].H "sp|P23396|RS3_HUMAN,tr|H0YEU2|H0YEU2_HUMAN,tr|E9PSF4|E9PSF4_HUMAN,tr|E9PL09|E9PL09_HUMAN" 4 2477.1925 0.59 20838 21971 3 2477.189999 826.7381 40S ribosomal protein S3 OS=Homo sapiens OX=9606 GN=RPS3 PE=1 SV=2 4.41 3669.6 - 2.03E+07 - - - -0.9959 - 3.872 0.661 - 575.5 1 2 0 -0.0025 22 0 0 0 1.91E+08 3.24E+08 - - - 9.1184 0.9999 221125_WJC_METTL3_EV_vs_WT_F02.21974.21974.2 5.26E-05 15/28 K.EIFLTVPVGGGESLR.L sp|Q53HL2|BOREA_HUMAN 1 1572.8512 1.24 20841 21974 2 1572.852268 787.4329 Borealin OS=Homo sapiens OX=9606 GN=CDCA8 PE=1 SV=2 4.53 3669.8 - 3.45E+06 - - - 0.7057 - 2.648 0.523 - 441.1 1 2 0 0.0011 15 0 0 0 7.23E+07 5.81E+07 - - - 5.2977 1 221125_WJC_METTL3_EV_vs_WT_F02.21975.21975.2 1.88E-13 25/38 R.LALVTGGEIASTFDHPELVK[136.11].L "sp|P78371|TCPB_HUMAN,tr|F8VQ14|F8VQ14_HUMAN,tr|F5GWF6|F5GWF6_HUMAN" 3 2104.1296 0.48 20842 21975 2 2104.12981 1053.0721 T-complex protein 1 subunit beta OS=Homo sapiens OX=9606 GN=CCT2 PE=1 SV=4 4.65 3669.9 - 3.11E+06 - - - 0.1136 - 4.244 0.597 - 1756.9 1 2 0 0.0002 20 0 0 0 8.82E+06 1.85E+07 - - - 7.0042 1 221125_WJC_METTL3_EV_vs_WT_F02.21976.21976.3 1.41E-06 16/60 K.ILDVASLEVLNEVNR[166.11]R[166.11].S sp|Q92616|GCN1_HUMAN 1 1859.038 0.6 20843 21976 3 1859.04013 620.6866 eIF-2-alpha kinase activator GCN1 OS=Homo sapiens OX=9606 GN=GCN1 PE=1 SV=6 4.68 3670 - 1.94E+06 - - - 1.1721 - 2.679 0.502 - 289.3 1 2 0 0.0022 16 0 0 0 7.92E+06 1.31E+07 - - - 6.6647 0.9999 221125_WJC_METTL3_EV_vs_WT_F02.21977.21977.2 5.65E-07 14/30 R.QPSADVLVATPGALWK[136.11].A sp|Q9NUL7|DDX28_HUMAN 1 1659.9076 1 20844 21977 2 1659.906766 830.9611 Probable ATP-dependent RNA helicase DDX28 OS=Homo sapiens OX=9606 GN=DDX28 PE=1 SV=2 5.84 3670.2 - 1.85E+06 - - - -0.4765 - 2.09 0.524 - 450.1 1 2 0 -0.0008 16 0 0 0 1.40E+07 1.40E+07 - - - 4.7234 0.9979 221125_WJC_METTL3_EV_vs_WT_F02.21981.21981.2 0.000662 20-Oct K.QININNPFVFK.H "sp|Q9UKF6|CPSF3_HUMAN,tr|G5E9W3|G5E9W3_HUMAN" 2 1332.719 1.86 20848 21981 2 1332.724087 667.3668 Cleavage and polyadenylation specificity factor subunit 3 OS=Homo sapiens OX=9606 GN=CPSF3 PE=1 SV=1 8.75 3670.6 - 1.03E+06 - - - 3.8013 - 1.994 0.387 - 364.2 1 2 0 0.0051 11 0 0 0 1.65E+07 8.86E+06 - - - 3.7648 0.9999 221125_WJC_METTL3_EV_vs_WT_F02.21982.21982.3 0.000294 Oct-48 R.AQEIDGQALLLLK.E "sp|Q8IXK0|PHC2_HUMAN,sp|Q8NDX5|PHC3_HUMAN,tr|H7C528|H7C528_HUMAN,tr|A0A0A0MSI2|A0A0A0MSI2_HUMAN,tr|B3KPJ4|B3KPJ4_HUMAN" 5 1410.8082 2.5 20849 21982 3 1410.808532 471.2767 Polyhomeotic-like protein 2 OS=Homo sapiens OX=9606 GN=PHC2 PE=1 SV=1 4.37 3670.8 - 942488 - - - 0.2141 - 1.881 0.421 - 162.9 1 2 0 0.0003 13 0 0 0 7.78E+06 3.11E+06 - - - 4.9467 0.9998 221125_WJC_METTL3_EV_vs_WT_F02.21984.21984.3 0.0583 13/44 K.DLVGLAIENLHK.S "sp|Q5VT06|CE350_HUMAN,tr|H0Y7F7|H0Y7F7_HUMAN" 2 1320.7402 2.31 20851 21984 3 1320.74093 441.254 Centrosome-associated protein 350 OS=Homo sapiens OX=9606 GN=CEP350 PE=1 SV=1 5.32 3671 - 706248 - - - 0.5898 - 2.132 0.347 - 121.2 1 2 0 0.0008 12 0 0 0 1.27E+07 5.51E+06 - - - 4.507 0.9963 221125_WJC_METTL3_EV_vs_WT_F02.21985.21985.3 0.044 Nov-40 K.EISHVLNFLIR.N "sp|Q8TED0|UTP15_HUMAN,tr|H0Y8P4|H0Y8P4_HUMAN" 2 1339.7612 0.99 20852 21985 3 1339.761211 447.5944 U3 small nucleolar RNA-associated protein 15 homolog OS=Homo sapiens OX=9606 GN=UTP15 PE=1 SV=3 6.85 3671.1 - 698718 - - - -0.0075 - 1.8 0.199 - 168 1 2 0 0 11 0 0 0 7.68E+06 7.76E+06 - - - 2.4285 0.9999 221125_WJC_METTL3_EV_vs_WT_F02.21986.21986.2 0.102 13/20 R.LFEAEAQDLFR[166.11].D sp|Q9H223|EHD4_HUMAN 1 1347.6698 1.39 20853 21986 2 1347.668944 674.8422 EH domain-containing protein 4 OS=Homo sapiens OX=9606 GN=EHD4 PE=1 SV=1 4.14 3671.3 - 673540 - - - -0.6619 - 2.597 0.443 - 612.8 1 2 0 -0.0009 11 0 0 0 6.78E+06 4.87E+06 - - - 4.8945 0.8502 221125_WJC_METTL3_EV_vs_WT_F02.21988.21988.3 0.00349 Nov-44 K.DLVGLAIENLHK[136.11].S "sp|Q5VT06|CE350_HUMAN,tr|H0Y7F7|H0Y7F7_HUMAN" 2 1328.7544 2.31 20855 21988 3 1329.752527 443.9254 Centrosome-associated protein 350 OS=Homo sapiens OX=9606 GN=CEP350 PE=1 SV=1 5.32 3671.6 - 592731 - - - 751.2118 - 1.797 0.318 - 93.2 1 2 0 0.9982 12 0 0 0 1.27E+07 5.51E+06 - - - 3.4335 1 221125_WJC_METTL3_EV_vs_WT_F02.21989.21989.2 1.44E-07 18/32 R.LVLDPGEAPLVPVYSGK.V sp|Q8NCF5|NF2IP_HUMAN 1 1752.9662 1.14 20856 21989 2 1752.968155 877.4904 NFATC2-interacting protein OS=Homo sapiens OX=9606 GN=NFATC2IP PE=1 SV=1 4.37 3671.7 - 543303 - - - 1.1221 - 2.807 0.568 - 722.1 1 2 0 0.002 17 0 0 0 7.95E+06 6.98E+06 - - - 5.7731 1 221125_WJC_METTL3_EV_vs_WT_F02.21991.21991.3 5.27E-07 19/56 R.LFPLIQAMHPTLAGK.L "sp|Q9H361|PABP3_HUMAN,sp|P11940|PABP1_HUMAN,tr|H0YAS6|H0YAS6_HUMAN,tr|H0YB75|H0YB75_HUMAN,tr|A0A7I2YQE4|A0A7I2YQE4_HUMAN,tr|A0A7I2V649|A0A7I2V649_HUMAN,tr|H0YAR2|H0YAR2_HUMAN,tr|E7ERJ7|E7ERJ7_HUMAN,tr|A0A7I2YQ88|A0A7I2YQ88_HUMAN,tr|A0A087WTT1|A0A087WTT1_HUMAN,tr|A0A7I2YQ90|A0A7I2YQ90_HUMAN,tr|A0A7I2V4N4|A0A7I2V4N4_HUMAN,tr|E7EQV3|E7EQV3_HUMAN" 13 1635.9171 1.27 20857 21991 3 1635.916094 546.313 Polyadenylate-binding protein 3 OS=Homo sapiens OX=9606 GN=PABPC3 PE=1 SV=2 8.76 3671.9 - 2.16E+07 - - - -0.596 - 3.729 0.636 - 381.9 1 2 0 -0.001 15 0 0 0 4.66E+08 3.67E+08 - - - 9.0648 1 221125_WJC_METTL3_EV_vs_WT_F02.21993.21993.3 2.67E-14 26/84 K.FVDGLMIHSGDPVNYYVDTAVR.H "sp|P23396|RS3_HUMAN,tr|H0YEU2|H0YEU2_HUMAN,tr|E9PSF4|E9PSF4_HUMAN,tr|E9PL09|E9PL09_HUMAN" 4 2467.1842 0.59 20858 21993 3 2467.18487 823.402 40S ribosomal protein S3 OS=Homo sapiens OX=9606 GN=RPS3 PE=1 SV=2 4.41 3672.1 - 5.63E+07 - - - 0.2732 - 3.965 0.728 - 697.1 1 2 0 0.0007 22 0 0 0 1.91E+08 3.24E+08 - - - 9.9221 1 221125_WJC_METTL3_EV_vs_WT_F02.21995.21995.3 1.01E-09 20/80 R.IFYHPETTQLMILSASEATVK.R "sp|P51114|FXR1_HUMAN,tr|E7EU85|E7EU85_HUMAN,tr|E9PFF5|E9PFF5_HUMAN,tr|C9IZ22|C9IZ22_HUMAN,tr|C9JZE0|C9JZE0_HUMAN,tr|C9JY20|C9JY20_HUMAN,tr|B4DXZ6|B4DXZ6_HUMAN" 7 2378.2192 1.67 20860 21995 3 2378.219271 793.747 Fragile X mental retardation syndrome-related protein 1 OS=Homo sapiens OX=9606 GN=FXR1 PE=1 SV=3 5.4 3672.2 - 8.04E+06 - - - 0.0366 - 3.891 0.624 - 510.6 1 2 0 0.0001 21 0 0 0 5.11E+07 3.07E+07 - - - 8.7543 1 221125_WJC_METTL3_EV_vs_WT_F02.21996.21996.3 1.67E-05 13/32 K.TWMWWHNFR.T "sp|O14744|ANM5_HUMAN,tr|G3V580|G3V580_HUMAN,tr|G3V2X6|G3V2X6_HUMAN,tr|G3V5L5|G3V5L5_HUMAN,tr|H0YJX6|H0YJX6_HUMAN" 5 1362.608 2.2 20861 21996 3 1362.607684 455.21 Protein arginine N-methyltransferase 5 OS=Homo sapiens OX=9606 GN=PRMT5 PE=1 SV=4 9.44 3672.2 - 6.11E+06 - - - -0.2547 - 2.207 0.474 - 383.7 1 2 0 -0.0003 9 0 0 0 2.93E+07 1.33E+07 - - - 6.2104 0.9996 221125_WJC_METTL3_EV_vs_WT_F02.21997.21997.4 1.39E-05 21/114 R.LALVTGGEIASTFDHPELVK.L "sp|P78371|TCPB_HUMAN,tr|F8VQ14|F8VQ14_HUMAN,tr|F5GWF6|F5GWF6_HUMAN" 3 2096.1154 0.56 20862 21997 4 2096.122077 525.0361 T-complex protein 1 subunit beta OS=Homo sapiens OX=9606 GN=CCT2 PE=1 SV=4 4.65 3672.3 - 4.60E+06 - - - 3.1993 - 3.41 0.408 - 252.9 1 2 0 0.0067 20 0 0 0 1.33E+07 2.38E+07 - - - 3.1855 0.9999 221125_WJC_METTL3_EV_vs_WT_F02.21998.21998.3 8.70E-05 15/52 R.TLTELILDAQEHVK.N "sp|P17480|UBF1_HUMAN,tr|E9PKP7|E9PKP7_HUMAN" 2 1608.8723 1.32 20863 21998 3 1608.873193 537.298 Nucleolar transcription factor 1 OS=Homo sapiens OX=9606 GN=UBTF PE=1 SV=1 4.65 3672.4 - 4.17E+06 - - - 0.5631 - 2.537 0.43 - 173.4 1 2 0 0.0009 14 0 0 0 2.04E+07 1.55E+07 - - - 5.8079 0.9998 221125_WJC_METTL3_EV_vs_WT_F02.21999.21999.2 0.000205 13/22 K.SDLLLEGFNNYR[166.11].F sp|P35580|MYH10_HUMAN 1 1449.7128 0.77 20864 21999 2 1449.710483 725.8637 Myosin-10 OS=Homo sapiens OX=9606 GN=MYH10 PE=1 SV=3 4.37 3672.4 - 3.93E+06 - - - -1.5734 - 2.528 0.441 - 706.4 1 2 0 -0.0023 12 0 0 0 3.49E+07 4.56E+07 - - - 4.7377 0.9999 221125_WJC_METTL3_EV_vs_WT_F02.22001.22001.3 1.02E-07 15/72 R.VIFPAAEDKDQDLITIIGK.E "sp|Q00341|VIGLN_HUMAN,tr|A0A024R4E5|A0A024R4E5_HUMAN,tr|H7C2D1|H7C2D1_HUMAN,tr|H0Y394|H0Y394_HUMAN" 4 2085.1358 1.53 20866 22001 3 2085.13666 696.0525 Vigilin OS=Homo sapiens OX=9606 GN=HDLBP PE=1 SV=2 4.23 3672.5 - 3.41E+06 - - - 0.4259 - 2.883 0.561 - 203.9 1 2 1 0.0009 19 0 0 0 1.88E+07 1.23E+07 - - - 7.3957 1 221125_WJC_METTL3_EV_vs_WT_F02.22002.22002.3 9.61E-05 Dec-32 K.TWMWWHNFR[166.11].T "sp|O14744|ANM5_HUMAN,tr|G3V580|G3V580_HUMAN,tr|G3V2X6|G3V2X6_HUMAN,tr|G3V5L5|G3V5L5_HUMAN,tr|H0YJX6|H0YJX6_HUMAN" 5 1372.6163 2.2 20867 22002 3 1372.616651 458.546 Protein arginine N-methyltransferase 5 OS=Homo sapiens OX=9606 GN=PRMT5 PE=1 SV=4 9.44 3672.6 - 3.37E+06 - - - 0.255 - 2.223 0.467 - 315.8 1 2 0 0.0003 9 0 0 0 2.93E+07 1.33E+07 - - - 6.1541 0.9998 221125_WJC_METTL3_EV_vs_WT_F02.22003.22003.2 3.25E-05 22-Nov K.TNNFSAFLANVR.K sp|Q9HBM1|SPC25_HUMAN 1 1352.6837 1.45 20868 22003 2 1352.683739 677.3491 Kinetochore protein Spc25 OS=Homo sapiens OX=9606 GN=SPC25 PE=1 SV=1 9.41 3672.7 - 2.76E+06 - - - 0.0296 - 2.207 0.431 - 477.6 1 2 0 0 12 0 0 0 1.63E+07 1.13E+07 - - - 4.3073 1 221125_WJC_METTL3_EV_vs_WT_F02.22004.22004.2 2.37E-14 21/42 K.FVDGLMIHSGDPVNYYVDTAVR[166.11].H "sp|P23396|RS3_HUMAN,tr|H0YEU2|H0YEU2_HUMAN,tr|E9PSF4|E9PSF4_HUMAN,tr|E9PL09|E9PL09_HUMAN" 4 2477.1925 -1 20869 22004 2 2477.193516 1239.6035 40S ribosomal protein S3 OS=Homo sapiens OX=9606 GN=RPS3 PE=1 SV=2 4.41 3672.8 - 1.65E+06 - - - 0.4239 - 4.005 0.719 - 760.4 1 2 0 0.001 22 0 0 0 0.00E+00 0.00E+00 - - - 7.7625 0.9997 221125_WJC_METTL3_EV_vs_WT_F02.22005.22005.3 0.00122 16/52 R.EAVELPLTHFELYK.Q sp|P43686|PRS6B_HUMAN 1 1687.8821 -1 20870 22005 3 1687.884131 563.6347 26S proteasome regulatory subunit 6B OS=Homo sapiens OX=9606 GN=PSMC4 PE=1 SV=2 4.75 3672.9 - 1.60E+06 - - - 1.1891 - 2.3 0.318 - 248.3 1 2 0 0.002 14 0 0 0 0.00E+00 0.00E+00 - - - 4.2983 1 221125_WJC_METTL3_EV_vs_WT_F02.22006.22006.2 2.46E-09 18/30 K.VIGNQSLVNELAFTAR.K sp|Q13011|ECH1_HUMAN 1 1730.9315 3.23 20871 22006 2 1730.940587 866.473 "Delta(3,5)-Delta(2,4)-dienoyl-CoA isomerase, mitochondrial OS=Homo sapiens OX=9606 GN=ECH1 PE=1 SV=2" 5.97 3673 - 1.52E+06 - - - 5.2301 - 3.468 0.629 - 1230.4 1 2 0 0.0091 16 0 0 0 2.83E+07 8.76E+06 - - - 6.7413 0.9994 221125_WJC_METTL3_EV_vs_WT_F02.22008.22008.2 0.000545 22-Oct R.IYGLGSLALYEK.A sp|P36542|ATPG_HUMAN 1 1325.7231 1.63 20873 22008 2 1325.726528 663.8688 "ATP synthase subunit gamma, mitochondrial OS=Homo sapiens OX=9606 GN=ATP5F1C PE=1 SV=1" 6 3673.3 - 1.01E+06 - - - 2.5827 - 2.233 0.406 - 225.7 1 2 0 0.0034 12 0 0 0 8.16E+06 5.02E+06 - - - 4.1524 0.9998 221125_WJC_METTL3_EV_vs_WT_F02.22010.22010.3 0.00211 Dec-36 K.LFDIRPIWSR.N "sp|Q9Y5Q8|TF3C5_HUMAN,tr|Q5T7U4|Q5T7U4_HUMAN,tr|Q5T7U0|Q5T7U0_HUMAN,tr|H7BY84|H7BY84_HUMAN" 4 1301.7244 -1 20875 22010 3 1301.724611 434.9154 General transcription factor 3C polypeptide 5 OS=Homo sapiens OX=9606 GN=GTF3C5 PE=1 SV=2 9.6 3673.5 - 552211 - - - 0.1306 - 1.87 0.386 - 210.4 1 2 0 0.0002 10 0 0 0 0.00E+00 0.00E+00 - - - 4.6715 0.9999 221125_WJC_METTL3_EV_vs_WT_F02.22012.22012.2 2.54E-05 18-Nov R.LGLEDFESLK.V sp|Q15208|STK38_HUMAN 1 1149.5918 5.14 20876 22012 2 1149.591663 575.8032 Serine\threonine-protein kinase 38 OS=Homo sapiens OX=9606 GN=STK38 PE=1 SV=1 4.14 3673.7 - 9.57E+06 - - - -0.08 - 2.36 0.548 - 290 1 2 0 -0.0001 10 0 0 0 1.16E+08 2.26E+07 - - - 5.4853 1 221125_WJC_METTL3_EV_vs_WT_F02.22013.22013.2 1.03E-06 14/24 K.QFLSDEQNILALR.S "sp|P39880|CUX1_HUMAN,tr|A0A2R8Y852|A0A2R8Y852_HUMAN,tr|A0A2R8YDI1|A0A2R8YDI1_HUMAN" 3 1545.8151 1.41 20877 22013 2 1545.816015 773.9148 Homeobox protein cut-like 1 OS=Homo sapiens OX=9606 GN=CUX1 PE=1 SV=3 4.37 3673.8 - 3.71E+06 - - - 0.5874 - 3.021 0.537 - 785.7 1 2 0 0.0009 13 0 0 0 9.84E+07 6.98E+07 - - - 5.8445 0.9998 221125_WJC_METTL3_EV_vs_WT_F02.22016.22016.2 0.00102 22-Dec K.SDLLLEGFNNYR.F sp|P35580|MYH10_HUMAN 1 1439.7045 0.76 20880 22016 2 1439.706033 720.8595 Myosin-10 OS=Homo sapiens OX=9606 GN=MYH10 PE=1 SV=3 4.37 3673.9 - 7.86E+06 - - - 1.069 - 2.507 0.425 - 517.5 1 2 0 0.0015 12 0 0 0 3.46E+07 4.56E+07 - - - 4.5978 1 221125_WJC_METTL3_EV_vs_WT_F02.22017.22017.3 1.29E-09 22/80 R.IFYHPETTQLMILSASEATVK[136.11].R "sp|P51114|FXR1_HUMAN,tr|E7EU85|E7EU85_HUMAN,tr|E9PFF5|E9PFF5_HUMAN,tr|C9IZ22|C9IZ22_HUMAN,tr|C9JZE0|C9JZE0_HUMAN,tr|C9JY20|C9JY20_HUMAN,tr|B4DXZ6|B4DXZ6_HUMAN" 7 2386.2334 1.63 20881 22017 3 2386.234296 796.4184 Fragile X mental retardation syndrome-related protein 1 OS=Homo sapiens OX=9606 GN=FXR1 PE=1 SV=3 5.4 3674 - 6.92E+06 - - - 0.3822 - 3.857 0.658 - 679.3 1 2 0 0.0009 21 0 0 0 5.01E+07 3.07E+07 - - - 9.1121 0.9998 221125_WJC_METTL3_EV_vs_WT_F02.22018.22018.2 2.54E-05 14/20 K.QVVNIPSFIVR.L sp|P46781|RS9_HUMAN 1 1270.7398 1.02 20882 22018 2 1270.741181 636.3772 40S ribosomal protein S9 OS=Homo sapiens OX=9606 GN=RPS9 PE=1 SV=3 9.75 3674 - 6.45E+06 - - - 1.1206 - 2.342 0.487 - 577.2 1 2 0 0.0014 11 0 0 0 1.21E+08 1.18E+08 - - - 4.9397 0.9998 221125_WJC_METTL3_EV_vs_WT_F02.22019.22019.2 0.000947 18-Oct K.NVQGIIEILK[136.11].G "sp|P42704|LPPRC_HUMAN,tr|A0A804HI14|A0A804HI14_HUMAN,tr|A0A804HL40|A0A804HL40_HUMAN,tr|A0A804HKJ0|A0A804HKJ0_HUMAN,tr|A0A804HKR3|A0A804HKR3_HUMAN,tr|A0A0C4DG06|A0A0C4DG06_HUMAN,tr|A0A804HIN4|A0A804HIN4_HUMAN,tr|A0A804HLG8|A0A804HLG8_HUMAN,tr|A0A804HIV5|A0A804HIV5_HUMAN,tr|A0A804HHY9|A0A804HHY9_HUMAN,tr|A0A804HJH8|A0A804HJH8_HUMAN,tr|B8ZZ38|B8ZZ38_HUMAN,tr|A0A804HI40|A0A804HI40_HUMAN,tr|A0A804HJZ1|A0A804HJZ1_HUMAN,tr|C9JCA9|C9JCA9_HUMAN,tr|A0A804HIQ7|A0A804HIQ7_HUMAN,tr|A0A804HK30|A0A804HK30_HUMAN,tr|A0A804HKI2|A0A804HKI2_HUMAN,tr|A0A804HKR5|A0A804HKR5_HUMAN,tr|A0A804HKX0|A0A804HKX0_HUMAN,tr|A0A804HIG4|A0A804HIG4_HUMAN,tr|A0A804HK02|A0A804HK02_HUMAN" 22 1133.69 0.82 20883 22019 2 1133.690488 567.8523 "Leucine-rich PPR motif-containing protein, mitochondrial OS=Homo sapiens OX=9606 GN=LRPPRC PE=1 SV=3" 6 3674 - 6.15E+06 - - - 0.4657 - 2.123 0.415 - 260.7 1 2 0 0.0005 10 0 0 0 3.71E+07 4.52E+07 - - - 4.2074 0.9997 221125_WJC_METTL3_EV_vs_WT_F02.22020.22020.2 0.00556 14-Aug K.IPDWFLNR.Q "sp|P62269|RS18_HUMAN,tr|J3JS69|J3JS69_HUMAN" 2 1059.5502 1.04 20884 22020 2 1059.5504 530.7824 40S ribosomal protein S18 OS=Homo sapiens OX=9606 GN=RPS18 PE=1 SV=3 5.84 3674.1 - 5.25E+06 - - - 0.2218 - 1.794 0.367 - 249.9 1 2 0 0.0002 8 0 0 0 4.19E+07 4.04E+07 - - - 3.5143 1 221125_WJC_METTL3_EV_vs_WT_F02.22021.22021.2 1.05E-08 16/28 K.LQPFATEADVEEALR[166.11].L "sp|P33992|MCM5_HUMAN,tr|B1AHB1|B1AHB1_HUMAN" 2 1697.85 0.47 20885 22021 2 1697.846649 849.9323 DNA replication licensing factor MCM5 OS=Homo sapiens OX=9606 GN=MCM5 PE=1 SV=5 4 3674.2 - 3.81E+06 - - - -1.9648 - 2.84 0.588 - 908.9 1 2 0 -0.0033 15 0 0 0 1.90E+07 4.03E+07 - - - 5.9492 1 221125_WJC_METTL3_EV_vs_WT_F02.22023.22023.2 2.36E-09 17/24 K.C[160.03]EFQDAYVLLSEK.K "sp|P10809|CH60_HUMAN,tr|A0A7I2V2X6|A0A7I2V2X6_HUMAN,tr|A0A7I2YQK6|A0A7I2YQK6_HUMAN,tr|A0A7I2V599|A0A7I2V599_HUMAN,tr|A0A7I2YQ71|A0A7I2YQ71_HUMAN,tr|A0A7I2V5M1|A0A7I2V5M1_HUMAN,tr|A0A7I2V5K3|A0A7I2V5K3_HUMAN,tr|A0A7I2V369|A0A7I2V369_HUMAN" 8 1600.7443 1.34 20887 22023 2 1600.743764 801.3794 "60 kDa heat shock protein, mitochondrial OS=Homo sapiens OX=9606 GN=HSPD1 PE=1 SV=2" 4.14 3674.3 - 3.50E+06 - - - -0.3411 - 3.07 0.679 - 1033.4 1 2 0 -0.0005 13 0 0 0 3.79E+09 2.82E+09 - - - 6.9347 0.9998 221125_WJC_METTL3_EV_vs_WT_F02.22024.22024.2 1.74E-05 15/24 K.VAVLQALASTVNR.D "sp|Q96EY7|PTCD3_HUMAN,tr|B8ZZQ4|B8ZZQ4_HUMAN" 2 1340.7776 1.14 20888 22024 2 1340.78061 671.3961 "Pentatricopeptide repeat domain-containing protein 3, mitochondrial OS=Homo sapiens OX=9606 GN=PTCD3 PE=1 SV=3" 9.72 3674.3 - 3.33E+06 - - - 2.2457 - 2.913 0.512 - 1037.6 1 2 0 0.003 13 0 0 0 1.96E+07 1.72E+07 - - - 5.5658 1 221125_WJC_METTL3_EV_vs_WT_F02.22025.22025.2 2.61E-08 17/30 K.LTNSPTVIVMVGLPAR.G "sp|Q16875|F263_HUMAN,tr|A0A1W2PR17|A0A1W2PR17_HUMAN,tr|Q5W015|Q5W015_HUMAN,tr|F2Z2I2|F2Z2I2_HUMAN,tr|Q5VX20|Q5VX20_HUMAN" 5 1666.944 4.33 20889 22025 2 1666.947141 834.4793 "6-phosphofructo-2-kinase\fructose-2,6-bisphosphatase 3 OS=Homo sapiens OX=9606 GN=PFKFB3 PE=1 SV=1" 9.75 3674.4 - 3.32E+06 - - - 1.8771 - 3.26 0.648 - 950.9 1 2 0 0.0031 16 0 0 0 3.31E+07 7.64E+06 - - - 6.7315 0.9999 221125_WJC_METTL3_EV_vs_WT_F02.22026.22026.2 4.48E-06 13/26 K.LTSAVSSLPELLEK[136.11].K "sp|Q8WVM8|SCFD1_HUMAN,tr|A0A7I2V4U2|A0A7I2V4U2_HUMAN,tr|A0A7I2V4B8|A0A7I2V4B8_HUMAN,tr|H0YIZ7|H0YIZ7_HUMAN,tr|A0A7I2V5Z4|A0A7I2V5Z4_HUMAN,tr|A0A7I2V3C9|A0A7I2V3C9_HUMAN,tr|B7Z5N7|B7Z5N7_HUMAN,tr|A0A7I2V5I2|A0A7I2V5I2_HUMAN,tr|A0A7I2V590|A0A7I2V590_HUMAN,tr|G3V5E2|G3V5E2_HUMAN,tr|A0A7I2V2U5|A0A7I2V2U5_HUMAN,tr|A0A7I2YQR2|A0A7I2YQR2_HUMAN,tr|A0A7I2V362|A0A7I2V362_HUMAN,tr|A0A7I2V448|A0A7I2V448_HUMAN,tr|A0A7I2V320|A0A7I2V320_HUMAN,tr|A0A7I2V3G4|A0A7I2V3G4_HUMAN,tr|A0A7I2V3B4|A0A7I2V3B4_HUMAN,tr|A0A7I2V5H5|A0A7I2V5H5_HUMAN,tr|A0A7I2V4R0|A0A7I2V4R0_HUMAN" 19 1493.8432 1.43 20890 22026 2 1493.844006 747.9289 Sec1 family domain-containing protein 1 OS=Homo sapiens OX=9606 GN=SCFD1 PE=1 SV=4 4.53 3674.4 - 3.12E+06 - - - 0.5221 - 2.691 0.54 - 521 1 2 0 0.0008 14 0 0 0 4.48E+07 3.14E+07 - - - 5.5133 0.9668 221125_WJC_METTL3_EV_vs_WT_F02.22027.22027.2 5.17E-07 15/28 K.DLANIAEVEVSIPAK.L "sp|Q00341|VIGLN_HUMAN,tr|A0A024R4E5|A0A024R4E5_HUMAN,tr|H7BZC3|H7BZC3_HUMAN,tr|H7C2D1|H7C2D1_HUMAN,tr|H0Y394|H0Y394_HUMAN" 5 1567.8457 1.19 20891 22027 2 1567.852879 784.9301 Vigilin OS=Homo sapiens OX=9606 GN=HDLBP PE=1 SV=2 4.14 3674.5 - 3.04E+06 - - - 4.5547 - 2.618 0.034 - 633.9 1 2 0 0.0071 15 0 0 0 3.14E+07 2.63E+07 - - - 1.656 0.9943 221125_WJC_METTL3_EV_vs_WT_F02.22028.22028.2 0.000389 15/26 L.GLETAGGVMTALIK[136.11].R "sp|P0DMV8|HS71A_HUMAN,sp|P34931|HS71L_HUMAN,sp|P0DMV9|HS71B_HUMAN,tr|Q53FA3|Q53FA3_HUMAN,tr|V9GZ37|V9GZ37_HUMAN,tr|A0A0G2JIW1|A0A0G2JIW1_HUMAN" 6 1367.7574 0.11 20892 22028 2 1367.758229 684.886 Heat shock 70 kDa protein 1A OS=Homo sapiens OX=9606 GN=HSPA1A PE=1 SV=1 6 3674.6 - 2.90E+06 - - - 0.6156 - 3.217 0.497 - 687.7 1 1 0 0.0008 14 0 0 0 2.09E+06 1.83E+07 - - - 5.6437 1 221125_WJC_METTL3_EV_vs_WT_F02.22029.22029.3 3.64E-06 15/56 K.NFINNPLAQADWAAK.K "sp|P35579|MYH9_HUMAN,tr|Q5BKV1|Q5BKV1_HUMAN,tr|B1AH99|B1AH99_HUMAN" 3 1671.8369 1.32 20893 22029 3 1671.838366 558.2862 Myosin-9 OS=Homo sapiens OX=9606 GN=MYH9 PE=1 SV=4 5.84 3674.6 - 2.00E+06 - - - 0.8739 - 2.574 0.53 - 302.2 1 2 0 0.0015 15 0 0 0 1.18E+07 8.93E+06 - - - 6.9156 1 221125_WJC_METTL3_EV_vs_WT_F02.22030.22030.3 6.05E-05 16/48 K.VAVLQALASTVNR[166.11].D "sp|Q96EY7|PTCD3_HUMAN,tr|B8ZZQ4|B8ZZQ4_HUMAN" 2 1350.7859 0.87 20894 22030 3 1350.78593 451.2692 "Pentatricopeptide repeat domain-containing protein 3, mitochondrial OS=Homo sapiens OX=9606 GN=PTCD3 PE=1 SV=3" 9.72 3674.7 - 1.98E+06 - - - 0.0452 - 3.155 0.442 - 564.4 1 2 0 0.0001 13 0 0 0 1.05E+07 1.21E+07 - - - 6.5831 0.9997 221125_WJC_METTL3_EV_vs_WT_F02.22031.22031.2 2.30E-07 28-Dec K.LQPFATEADVEEALR.L "sp|P33992|MCM5_HUMAN,tr|B1AHB1|B1AHB1_HUMAN" 2 1687.8417 0.47 20895 22031 2 1687.837351 844.9281 DNA replication licensing factor MCM5 OS=Homo sapiens OX=9606 GN=MCM5 PE=1 SV=5 4 3674.8 - 1.97E+06 - - - -2.5856 - 2.442 0.579 - 424.2 1 2 0 -0.0044 15 0 0 0 1.90E+07 4.03E+07 - - - 5.5112 0.9999 221125_WJC_METTL3_EV_vs_WT_F02.22033.22033.3 0.000385 20/52 R.VLEALLPLK[136.11]GLEER[166.11].V "sp|P49327|FAS_HUMAN,tr|A0A0U1RQF0|A0A0U1RQF0_HUMAN" 2 1596.957 -1 20896 22033 3 1596.958436 533.3263 Fatty acid synthase OS=Homo sapiens OX=9606 GN=FASN PE=1 SV=3 4.79 3675.1 - 1.40E+06 - - - 0.9218 - 3.384 0.44 - 614.2 1 2 1 0.0015 14 0 0 0 0.00E+00 0.00E+00 - - - 6.6848 1 221125_WJC_METTL3_EV_vs_WT_F02.22035.22035.3 1.36E-06 13/48 K.C[160.03]EFQDAYVLLSEK.K "sp|P10809|CH60_HUMAN,tr|A0A7I2V2X6|A0A7I2V2X6_HUMAN,tr|A0A7I2YQK6|A0A7I2YQK6_HUMAN,tr|A0A7I2V599|A0A7I2V599_HUMAN,tr|A0A7I2YQ71|A0A7I2YQ71_HUMAN,tr|A0A7I2V5M1|A0A7I2V5M1_HUMAN,tr|A0A7I2V5K3|A0A7I2V5K3_HUMAN,tr|A0A7I2V369|A0A7I2V369_HUMAN" 8 1600.7443 1.37 20898 22035 3 1600.74553 534.5887 "60 kDa heat shock protein, mitochondrial OS=Homo sapiens OX=9606 GN=HSPD1 PE=1 SV=2" 4.14 3675.1 - 1.55E+07 - - - 0.7621 - 2.739 0.608 - 223.4 1 2 0 0.0012 13 0 0 0 1.66E+09 1.21E+09 - - - 8.0501 0.9999 221125_WJC_METTL3_EV_vs_WT_F02.22036.22036.3 1.72E-08 Nov-48 K.C[160.03]EFQDAYVLLSEK[136.11].K "sp|P10809|CH60_HUMAN,tr|A0A7I2V2X6|A0A7I2V2X6_HUMAN,tr|A0A7I2YQK6|A0A7I2YQK6_HUMAN,tr|A0A7I2V599|A0A7I2V599_HUMAN,tr|A0A7I2YQ71|A0A7I2YQ71_HUMAN,tr|A0A7I2V5M1|A0A7I2V5M1_HUMAN,tr|A0A7I2V5K3|A0A7I2V5K3_HUMAN,tr|A0A7I2V369|A0A7I2V369_HUMAN" 8 1608.7585 1.37 20899 22036 3 1608.758539 537.2601 "60 kDa heat shock protein, mitochondrial OS=Homo sapiens OX=9606 GN=HSPD1 PE=1 SV=2" 4.14 3675.2 - 1.50E+07 - - - 0.018 - 2.124 0.452 - 168.6 1 2 0 0 13 0 0 0 1.66E+09 1.21E+09 - - - 5.6218 1 221125_WJC_METTL3_EV_vs_WT_F02.22039.22039.3 5.60E-06 17/60 K.LTNSPTVIVMVGLPAR.G "sp|Q16875|F263_HUMAN,tr|A0A1W2PR17|A0A1W2PR17_HUMAN,tr|Q5W015|Q5W015_HUMAN,tr|F2Z2I2|F2Z2I2_HUMAN,tr|Q5VX20|Q5VX20_HUMAN" 5 1666.944 3.42 20902 22039 3 1666.945978 556.6553 "6-phosphofructo-2-kinase\fructose-2,6-bisphosphatase 3 OS=Homo sapiens OX=9606 GN=PFKFB3 PE=1 SV=1" 9.75 3675.4 - 3.32E+06 - - - 1.1794 - 2.923 0.503 - 328.9 1 2 0 0.002 16 0 0 0 1.50E+07 4.38E+06 - - - 6.8996 0.9969 221125_WJC_METTL3_EV_vs_WT_F02.22041.22041.2 0.155 14-Jul R.NLIEWLNK[136.11].Y sp|Q96DG6|CMBL_HUMAN 1 1036.5797 1 20904 22041 2 1036.580608 519.2971 Carboxymethylenebutenolidase homolog OS=Homo sapiens OX=9606 GN=CMBL PE=1 SV=1 6 3675.5 - 2.89E+06 - - - 0.8943 - 1.497 0.186 - 170.3 1 2 0 0.0009 8 0 0 0 1.69E+07 1.69E+07 - - - 1.6313 0.9999 221125_WJC_METTL3_EV_vs_WT_F02.22043.22043.2 4.84E-07 24-Nov K.IYVDDGLISLQVK[136.11].Q "sp|P14618|KPYM_HUMAN,tr|H3BQ34|H3BQ34_HUMAN,tr|B4DNK4|B4DNK4_HUMAN,tr|A0A804F6T5|A0A804F6T5_HUMAN,tr|H3BTN5|H3BTN5_HUMAN,tr|A0A804F729|A0A804F729_HUMAN" 6 1469.8221 1.01 20906 22043 2 1469.822879 735.9183 Pyruvate kinase PKM OS=Homo sapiens OX=9606 GN=PKM PE=1 SV=4 4.21 3675.7 - 2.58E+06 - - - 0.5327 - 2.276 0.582 - 286.1 1 2 0 0.0008 13 0 0 0 2.43E+07 2.42E+07 - - - 5.4502 0.9999 221125_WJC_METTL3_EV_vs_WT_F02.22045.22045.2 6.33E-06 15/30 K.IASLPQEVQDVSLLEK.L "sp|Q9NQG5|RPR1B_HUMAN,tr|A2A2M0|A2A2M0_HUMAN" 2 1767.9618 2.94 20908 22045 2 1767.960612 884.9882 Regulation of nuclear pre-mRNA domain-containing protein 1B OS=Homo sapiens OX=9606 GN=RPRD1B PE=1 SV=1 4.14 3675.9 - 2.04E+06 - - - -0.6895 - 2.794 0.519 - 534.3 1 2 0 -0.0012 16 0 0 0 1.68E+08 5.69E+07 - - - 5.4 0.9987 221125_WJC_METTL3_EV_vs_WT_F02.22046.22046.2 0.000633 14/24 R.EQLWLANEGLITR.L "sp|P46940|IQGA1_HUMAN,tr|A0A087WWP1|A0A087WWP1_HUMAN,tr|H0YLE8|H0YLE8_HUMAN,tr|A0A0J9YXZ5|A0A0J9YXZ5_HUMAN" 4 1541.8202 1.72 20909 22046 2 1541.824678 771.9174 Ras GTPase-activating-like protein IQGAP1 OS=Homo sapiens OX=9606 GN=IQGAP1 PE=1 SV=1 4.53 3676 - 2.03E+06 - - - 2.9095 - 2.747 0.267 - 880.4 1 2 0 0.0045 13 0 0 0 1.59E+07 9.25E+06 - - - 3.6052 1 221125_WJC_METTL3_EV_vs_WT_F02.22051.22051.2 7.38E-07 16/32 K.VFPGSTTEDYNLIVIER[166.11].G "sp|Q13263|TIF1B_HUMAN,tr|M0R0K9|M0R0K9_HUMAN" 2 1961.9974 0.63 20914 22051 2 1961.998935 982.006 Transcription intermediary factor 1-beta OS=Homo sapiens OX=9606 GN=TRIM28 PE=1 SV=5 4.14 3676.5 - 1.62E+06 - - - 0.7936 - 3.372 0.586 - 994.3 1 2 0 0.0016 17 0 0 0 2.05E+07 3.24E+07 - - - 6.3571 1 221125_WJC_METTL3_EV_vs_WT_F02.22054.22054.3 1.90E-05 19/56 R.LFPLIQAMHPTLAGK[136.11].L "sp|Q9H361|PABP3_HUMAN,sp|P11940|PABP1_HUMAN,tr|H0YAS6|H0YAS6_HUMAN,tr|H0YB75|H0YB75_HUMAN,tr|A0A7I2YQE4|A0A7I2YQE4_HUMAN,tr|A0A7I2V649|A0A7I2V649_HUMAN,tr|H0YAR2|H0YAR2_HUMAN,tr|E7ERJ7|E7ERJ7_HUMAN,tr|A0A7I2YQ88|A0A7I2YQ88_HUMAN,tr|A0A087WTT1|A0A087WTT1_HUMAN,tr|A0A7I2YQ90|A0A7I2YQ90_HUMAN,tr|A0A7I2V4N4|A0A7I2V4N4_HUMAN,tr|E7EQV3|E7EQV3_HUMAN" 13 1643.9313 1.31 20916 22054 3 1643.931132 548.9844 Polyadenylate-binding protein 3 OS=Homo sapiens OX=9606 GN=PABPC3 PE=1 SV=2 8.76 3676.8 - 2.00E+07 - - - -0.0833 - 3.557 0.529 - 458.3 1 2 0 -0.0001 15 0 0 0 2.29E+08 1.74E+08 - - - 7.7489 1 221125_WJC_METTL3_EV_vs_WT_F02.22057.22057.2 0.000801 14/28 R.KPLVIIAEDVDGEAL.S "sp|P10809|CH60_HUMAN,tr|A0A7I2V2X6|A0A7I2V2X6_HUMAN,tr|A0A7I2YQK6|A0A7I2YQK6_HUMAN,tr|A0A7I2V599|A0A7I2V599_HUMAN,tr|A0A7I2YQ71|A0A7I2YQ71_HUMAN,tr|A0A7I2V5M1|A0A7I2V5M1_HUMAN,tr|A0A7I2V5K3|A0A7I2V5K3_HUMAN,tr|A0A7I2V369|A0A7I2V369_HUMAN" 8 1580.8661 1.68 20919 22057 2 1580.864945 791.4403 "60 kDa heat shock protein, mitochondrial OS=Homo sapiens OX=9606 GN=HSPD1 PE=1 SV=2" 3.92 3676.9 - 1.50E+07 - - - -0.7553 - 3.236 0.561 - 804.5 1 1 0 -0.0012 15 0 0 0 1.24E+08 7.38E+07 - - - 6.0713 1 221125_WJC_METTL3_EV_vs_WT_F02.22058.22058.2 4.42E-09 13/28 R.K[136.11]PLVIIAEDVDGEAL.S "sp|P10809|CH60_HUMAN,tr|A0A7I2V2X6|A0A7I2V2X6_HUMAN,tr|A0A7I2YQK6|A0A7I2YQK6_HUMAN,tr|A0A7I2V599|A0A7I2V599_HUMAN,tr|A0A7I2YQ71|A0A7I2YQ71_HUMAN,tr|A0A7I2V5M1|A0A7I2V5M1_HUMAN,tr|A0A7I2V5K3|A0A7I2V5K3_HUMAN,tr|A0A7I2V369|A0A7I2V369_HUMAN" 8 1588.8803 1.68 20920 22058 2 1588.88015 795.4474 "60 kDa heat shock protein, mitochondrial OS=Homo sapiens OX=9606 GN=HSPD1 PE=1 SV=2" 3.92 3677 - 1.12E+07 - - - -0.119 - 2.934 0.628 - 701.9 1 1 0 -0.0002 15 0 0 0 1.24E+08 7.38E+07 - - - 6.3256 0.9999 221125_WJC_METTL3_EV_vs_WT_F02.22060.22060.2 1.56E-06 24-Dec K.IYVDDGLISLQVK.Q "sp|P14618|KPYM_HUMAN,tr|H3BQ34|H3BQ34_HUMAN,tr|B4DNK4|B4DNK4_HUMAN,tr|A0A804F6T5|A0A804F6T5_HUMAN,tr|H3BTN5|H3BTN5_HUMAN,tr|A0A804F729|A0A804F729_HUMAN" 6 1461.8079 1.01 20922 22060 2 1461.806463 731.9112 Pyruvate kinase PKM OS=Homo sapiens OX=9606 GN=PKM PE=1 SV=4 4.21 3677 - 5.68E+06 - - - -0.9803 - 2.34 0.557 - 342.2 1 2 0 -0.0014 13 0 0 0 2.43E+07 2.42E+07 - - - 5.3365 1 221125_WJC_METTL3_EV_vs_WT_F02.22062.22062.2 1.26E-06 16/28 R.LLGVPIIVQASQAEK.N "sp|Q86U06|RBM23_HUMAN,tr|G3XAP0|G3XAP0_HUMAN,tr|G3V546|G3V546_HUMAN" 3 1564.9188 1.44 20924 22062 2 1564.918498 783.4667 Probable RNA-binding protein 23 OS=Homo sapiens OX=9606 GN=RBM23 PE=1 SV=1 6 3677.1 - 4.79E+06 - - - -0.2211 - 2.745 0.591 - 690.6 1 2 0 -0.0003 15 0 0 0 1.14E+08 7.92E+07 - - - 5.8886 1 221125_WJC_METTL3_EV_vs_WT_F02.22064.22064.3 3.51E-10 16/56 R.LHPVILASIVDSYER.R "sp|O00303|EIF3F_HUMAN,tr|A0A1W2PP79|A0A1W2PP79_HUMAN,tr|H0YDT6|H0YDT6_HUMAN,tr|A0A7I2V4S2|A0A7I2V4S2_HUMAN,tr|A0A7I2YQA0|A0A7I2YQA0_HUMAN" 5 1710.9305 1.09 20926 22064 3 1710.931919 571.3174 Eukaryotic translation initiation factor 3 subunit F OS=Homo sapiens OX=9606 GN=EIF3F PE=1 SV=1 5.32 3677.2 - 3.22E+06 - - - 0.8463 - 3.286 0.562 - 453.5 1 2 0 0.0014 15 0 0 0 6.74E+07 6.16E+07 - - - 7.9096 0.9999 221125_WJC_METTL3_EV_vs_WT_F02.22066.22066.3 3.83E-11 15/56 R.LHPVILASIVDSYER[166.11].R "sp|O00303|EIF3F_HUMAN,tr|A0A1W2PP79|A0A1W2PP79_HUMAN,tr|H0YDT6|H0YDT6_HUMAN,tr|A0A7I2V4S2|A0A7I2V4S2_HUMAN,tr|A0A7I2YQA0|A0A7I2YQA0_HUMAN" 5 1720.9387 1.09 20928 22066 3 1720.932472 574.6535 Eukaryotic translation initiation factor 3 subunit F OS=Homo sapiens OX=9606 GN=EIF3F PE=1 SV=1 5.32 3677.4 - 2.65E+06 - - - -3.6428 - 2.902 0.621 - 351.9 1 2 0 -0.0063 15 0 0 0 6.61E+07 6.04E+07 - - - 8.2418 1 221125_WJC_METTL3_EV_vs_WT_F02.22069.22069.3 1.54E-07 Dec-44 R.EWTDGLFTHVLR[166.11].K "sp|Q14204|DYHC1_HUMAN,tr|A0A7P0T8N2|A0A7P0T8N2_HUMAN,tr|A0A7P0T9C4|A0A7P0T9C4_HUMAN,tr|A0A7P0TBJ7|A0A7P0TBJ7_HUMAN,tr|A0A804HHY6|A0A804HHY6_HUMAN,tr|A0A7P0T9K2|A0A7P0T9K2_HUMAN,tr|A0A7P0TB64|A0A7P0TB64_HUMAN,tr|A0A2R8Y706|A0A2R8Y706_HUMAN,tr|A0A7P0T916|A0A7P0T916_HUMAN,tr|A0A7P0TB75|A0A7P0TB75_HUMAN,tr|A0A7P0T8W5|A0A7P0T8W5_HUMAN,tr|A0A7P0T9S3|A0A7P0T9S3_HUMAN,tr|A0A7P0TAF3|A0A7P0TAF3_HUMAN,tr|A0A7P0T9F1|A0A7P0T9F1_HUMAN,tr|A0A7P0TAW9|A0A7P0TAW9_HUMAN,tr|A0A2R8YGC7|A0A2R8YGC7_HUMAN,tr|A0A7P0TA13|A0A7P0TA13_HUMAN,tr|A0A7P0T934|A0A7P0T934_HUMAN,tr|A0A7P0TAV5|A0A7P0TAV5_HUMAN,tr|A0A7P0T7V5|A0A7P0T7V5_HUMAN,tr|A0A7P0T9R4|A0A7P0T9R4_HUMAN,tr|A0A2R8Y5T0|A0A2R8Y5T0_HUMAN,tr|A0A7P0T990|A0A7P0T990_HUMAN,tr|A0A7P0T942|A0A7P0T942_HUMAN,tr|A0A2R8YFZ7|A0A2R8YFZ7_HUMAN,tr|A0A7P0T825|A0A7P0T825_HUMAN,tr|A0A2R8Y6H2|A0A2R8Y6H2_HUMAN,tr|A0A7P0TAM4|A0A7P0TAM4_HUMAN" 28 1482.7495 0.96 20931 22069 3 1482.748623 495.2571 Cytoplasmic dynein 1 heavy chain 1 OS=Homo sapiens OX=9606 GN=DYNC1H1 PE=1 SV=5 5.32 3677.8 - 1.87E+06 - - - -0.58 - 2.683 0.576 - 221.5 1 2 0 -0.0009 12 0 0 0 1.12E+07 1.17E+07 - - - 7.6972 0.9999 221125_WJC_METTL3_EV_vs_WT_F02.22070.22070.2 2.97E-08 13/30 K.IASLPQEVQDVSLLEK[136.11].L "sp|Q9NQG5|RPR1B_HUMAN,tr|A2A2M0|A2A2M0_HUMAN" 2 1775.976 2.94 20932 22070 2 1775.974964 888.9953 Regulation of nuclear pre-mRNA domain-containing protein 1B OS=Homo sapiens OX=9606 GN=RPRD1B PE=1 SV=1 4.14 3677.9 - 1.86E+06 - - - -0.6008 - 2.768 0.495 - 471.9 1 2 0 -0.0011 16 0 0 0 1.68E+08 5.69E+07 - - - 5.1998 1 221125_WJC_METTL3_EV_vs_WT_F02.22072.22072.3 1.84E-05 14/56 R.LLGVPIIVQASQAEK[136.11].N "sp|Q86U06|RBM23_HUMAN,tr|G3XAP0|G3XAP0_HUMAN,tr|G3V546|G3V546_HUMAN" 3 1572.933 1.45 20934 22072 3 1572.932687 525.3183 Probable RNA-binding protein 23 OS=Homo sapiens OX=9606 GN=RBM23 PE=1 SV=1 6 3678.1 - 1.48E+06 - - - -0.227 - 2.833 0.425 - 225.5 1 2 0 -0.0004 15 0 0 0 3.51E+07 2.42E+07 - - - 5.9955 1 221125_WJC_METTL3_EV_vs_WT_F02.22080.22080.3 1.63E-05 17/44 R.EWTDGLFTHVLR.K "sp|Q14204|DYHC1_HUMAN,tr|A0A7P0T8N2|A0A7P0T8N2_HUMAN,tr|A0A7P0T9C4|A0A7P0T9C4_HUMAN,tr|A0A7P0TBJ7|A0A7P0TBJ7_HUMAN,tr|A0A804HHY6|A0A804HHY6_HUMAN,tr|A0A7P0T9K2|A0A7P0T9K2_HUMAN,tr|A0A7P0TB64|A0A7P0TB64_HUMAN,tr|A0A2R8Y706|A0A2R8Y706_HUMAN,tr|A0A7P0T916|A0A7P0T916_HUMAN,tr|A0A7P0TB75|A0A7P0TB75_HUMAN,tr|A0A7P0T8W5|A0A7P0T8W5_HUMAN,tr|A0A7P0T9S3|A0A7P0T9S3_HUMAN,tr|A0A7P0TAF3|A0A7P0TAF3_HUMAN,tr|A0A7P0T9F1|A0A7P0T9F1_HUMAN,tr|A0A7P0TAW9|A0A7P0TAW9_HUMAN,tr|A0A2R8YGC7|A0A2R8YGC7_HUMAN,tr|A0A7P0TA13|A0A7P0TA13_HUMAN,tr|A0A7P0T934|A0A7P0T934_HUMAN,tr|A0A7P0TAV5|A0A7P0TAV5_HUMAN,tr|A0A7P0T7V5|A0A7P0T7V5_HUMAN,tr|A0A7P0T9R4|A0A7P0T9R4_HUMAN,tr|A0A2R8Y5T0|A0A2R8Y5T0_HUMAN,tr|A0A7P0T990|A0A7P0T990_HUMAN,tr|A0A7P0T942|A0A7P0T942_HUMAN,tr|A0A2R8YFZ7|A0A2R8YFZ7_HUMAN,tr|A0A7P0T825|A0A7P0T825_HUMAN,tr|A0A2R8Y6H2|A0A2R8Y6H2_HUMAN,tr|A0A7P0TAM4|A0A7P0TAM4_HUMAN" 28 1472.7412 0.96 20941 22080 3 1472.740863 491.921 Cytoplasmic dynein 1 heavy chain 1 OS=Homo sapiens OX=9606 GN=DYNC1H1 PE=1 SV=5 5.32 3678.8 - 2.12E+06 - - - -0.2377 - 3.098 0.557 - 557 1 2 0 -0.0004 12 0 0 0 1.12E+07 1.17E+07 - - - 7.8842 1 221125_WJC_METTL3_EV_vs_WT_F02.22081.22081.2 6.75E-09 23/30 K.K[136.11]VSQEILELLNTTTAK[136.11].E "sp|Q86U44|MTA70_HUMAN,tr|H0YFV6|H0YFV6_HUMAN" 2 1803.0324 0.001 20942 22081 2 1803.029516 902.5235 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 6.14 3678.9 - 1.91E+06 - - - -1.6162 - 4.449 0.662 - 1671.4 1 2 0 -0.0029 16 0 0 0 0.00E+00 8.05E+07 - - - 7.5994 1 221125_WJC_METTL3_EV_vs_WT_F02.22082.22082.2 3.98E-09 16/32 K.ASLLTDEEDVDMALDQR.F "sp|P52948|NUP98_HUMAN,tr|A0A3B3ITD8|A0A3B3ITD8_HUMAN,tr|H7C3P6|H7C3P6_HUMAN" 3 1919.8782 6.58 20943 22082 2 1919.875104 960.9464 Nuclear pore complex protein Nup98-Nup96 OS=Homo sapiens OX=9606 GN=NUP98 PE=1 SV=4 3.66 3679.1 - 1.89E+06 - - - -1.6319 - 3.589 0.666 - 613.7 1 2 0 -0.0031 17 0 0 0 7.62E+06 1.16E+06 - - - 7.1008 0.9999 221125_WJC_METTL3_EV_vs_WT_F02.22084.22084.3 4.83E-05 Dec-52 R.GSFGELALMYNTPR.A "sp|P13861|KAP2_HUMAN,sp|P31323|KAP3_HUMAN,tr|H7C1L0|H7C1L0_HUMAN" 3 1554.7501 0.29 20945 22084 3 1554.747791 519.2573 cAMP-dependent protein kinase type II-alpha regulatory subunit OS=Homo sapiens OX=9606 GN=PRKAR2A PE=1 SV=2 6 3679.3 - 997402 - - - -1.462 - 1.914 0.451 - 169.6 1 2 0 -0.0023 14 0 0 0 7.51E+06 2.56E+07 - - - 5.2928 0.9999 221125_WJC_METTL3_EV_vs_WT_F02.22088.22088.2 0.000117 22-Sep R.GSDVIIMLVGNK.T "sp|P20340|RAB6A_HUMAN,sp|Q9NRW1|RAB6B_HUMAN,tr|J3KR73|J3KR73_HUMAN,tr|C9JU14|C9JU14_HUMAN" 4 1244.6799 1.23 20947 22088 2 1244.679604 623.3472 Ras-related protein Rab-6A OS=Homo sapiens OX=9606 GN=RAB6A PE=1 SV=3 5.84 3679.8 - 1.57E+07 - - - -0.2049 - 2.221 0.507 - 376.5 1 2 0 -0.0003 12 0 0 0 1.25E+08 1.02E+08 - - - 4.8852 0.9998 221125_WJC_METTL3_EV_vs_WT_F02.22089.22089.2 1.06E-06 26-Dec R.GLGWVQFSSEEGLR.N "sp|Q9GZT3|SLIRP_HUMAN,tr|H0YJW7|H0YJW7_HUMAN,tr|A0A087WUN7|A0A087WUN7_HUMAN,tr|G3V2S9|G3V2S9_HUMAN,tr|H0YJ40|H0YJ40_HUMAN,tr|G3V4X6|G3V4X6_HUMAN" 6 1563.7682 1.23 20948 22089 2 1563.765915 782.8914 "SRA stem-loop-interacting RNA-binding protein, mitochondrial OS=Homo sapiens OX=9606 GN=SLIRP PE=1 SV=1" 4.53 3679.9 - 8.90E+06 - - - -1.4337 - 2.311 0.503 - 367.9 1 2 0 -0.0022 14 0 0 0 6.67E+08 5.43E+08 - - - 4.8576 1 221125_WJC_METTL3_EV_vs_WT_F02.22090.22090.3 1.04E-05 17/60 K.K[136.11]VSQEILELLNTTTAK[136.11].E "sp|Q86U44|MTA70_HUMAN,tr|H0YFV6|H0YFV6_HUMAN" 2 1803.0324 0.01 20949 22090 3 1803.030639 602.0181 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 6.14 3679.9 - 1.23E+07 - - - -0.9933 - 3.716 0.67 - 551.4 1 2 0 -0.0018 16 0 0 0 2.83E+06 4.81E+08 - - - 9.3774 1 221125_WJC_METTL3_EV_vs_WT_F02.22095.22095.2 1.09E-11 18/30 K.IYADTFGDINYQEFAK[136.11].R sp|Q15029|U5S1_HUMAN 1 1901.8927 1.8 20954 22095 2 1901.885863 951.9536 116 kDa U5 small nuclear ribonucleoprotein component OS=Homo sapiens OX=9606 GN=EFTUD2 PE=1 SV=1 4.03 3680.3 - 2.65E+06 - - - -3.5922 - 3.525 0.704 - 760.2 1 2 0 -0.0068 16 0 0 0 5.38E+07 2.99E+07 - - - 7.3361 0.9988 221125_WJC_METTL3_EV_vs_WT_F02.22096.22096.3 0.0008 Nov-40 K.GKFDVQWIFVK.D sp|Q9BYJ9|YTHD1_HUMAN 1 1365.7445 1.03 20955 22096 3 1365.740291 456.2554 YTH domain-containing family protein 1 OS=Homo sapiens OX=9606 GN=YTHDF1 PE=1 SV=1 8.59 3680.4 - 2.23E+06 - - - -3.0877 - 2.285 0.425 - 276.8 1 2 1 -0.0042 11 0 0 0 1.74E+07 1.69E+07 - - - 5.6247 0.999 221125_WJC_METTL3_EV_vs_WT_F02.22099.22099.3 0.00182 14/68 K.VLPGDYEILATHPTWALK.E "sp|Q15155|NOMO1_HUMAN,sp|Q5JPE7|NOMO2_HUMAN,sp|P69849|NOMO3_HUMAN,tr|A0A7I2V686|A0A7I2V686_HUMAN,tr|A0A7I2V6B0|A0A7I2V6B0_HUMAN,tr|A0A7I2V4D7|A0A7I2V4D7_HUMAN,tr|A0A7I2V4T6|A0A7I2V4T6_HUMAN,tr|A0A0G2JP90|A0A0G2JP90_HUMAN,tr|A0A087X117|A0A087X117_HUMAN,tr|A0A7I2V2V8|A0A7I2V2V8_HUMAN,tr|A0A0G2JN29|A0A0G2JN29_HUMAN,tr|A0A7I2V2Z5|A0A7I2V2Z5_HUMAN,tr|A0A087WW46|A0A087WW46_HUMAN,tr|J3KN36|J3KN36_HUMAN" 14 2023.0779 2.02 20958 22099 3 2023.076635 675.3666 Nodal modulator 1 OS=Homo sapiens OX=9606 GN=NOMO1 PE=1 SV=5 5.32 3680.8 - 1.93E+06 - - - -0.607 - 1.802 0.297 - 74.7 1 2 0 -0.0012 18 0 0 0 1.75E+07 8.67E+06 - - - 3.3173 0.9999 221125_WJC_METTL3_EV_vs_WT_F02.22105.22105.2 2.63E-06 15/26 R.GLGWVQFSSEEGLR[166.11].N "sp|Q9GZT3|SLIRP_HUMAN,tr|H0YJW7|H0YJW7_HUMAN,tr|A0A087WUN7|A0A087WUN7_HUMAN,tr|G3V2S9|G3V2S9_HUMAN,tr|H0YJ40|H0YJ40_HUMAN,tr|G3V4X6|G3V4X6_HUMAN" 6 1573.7764 1.23 20962 22105 2 1573.775529 787.8955 "SRA stem-loop-interacting RNA-binding protein, mitochondrial OS=Homo sapiens OX=9606 GN=SLIRP PE=1 SV=1" 4.53 3681.6 - 2.82E+07 - - - -0.5706 - 2.806 0.454 - 809.5 1 2 0 -0.0009 14 0 0 0 6.73E+08 5.48E+08 - - - 4.9831 0.9998 221125_WJC_METTL3_EV_vs_WT_F02.22106.22106.2 0.121 22-Nov R.GSDVIIMLVGNK[136.11].T "sp|P20340|RAB6A_HUMAN,sp|Q9NRW1|RAB6B_HUMAN,tr|J3KR73|J3KR73_HUMAN,tr|C9JU14|C9JU14_HUMAN" 4 1252.6941 1.23 20963 22106 2 1252.692695 627.3543 Ras-related protein Rab-6A OS=Homo sapiens OX=9606 GN=RAB6A PE=1 SV=3 5.84 3681.6 - 1.19E+07 - - - -1.0889 - 2.462 0.412 - 592.2 1 2 0 -0.0014 12 0 0 0 1.25E+08 1.02E+08 - - - 4.4542 1 221125_WJC_METTL3_EV_vs_WT_F02.22107.22107.2 9.61E-12 16/30 K.IYADTFGDINYQEFAK.R sp|Q15029|U5S1_HUMAN 1 1893.8785 1.7 20964 22107 2 1893.870407 947.9465 116 kDa U5 small nuclear ribonucleoprotein component OS=Homo sapiens OX=9606 GN=EFTUD2 PE=1 SV=1 4.03 3681.7 - 5.46E+06 - - - -4.2706 - 3.324 0.755 - 703.8 1 2 0 -0.0081 16 0 0 0 5.88E+07 3.47E+07 - - - 7.568 1 221125_WJC_METTL3_EV_vs_WT_F02.22108.22108.3 0.00445 15/56 R.LLGVPIIVQASQAEK.N "sp|Q86U06|RBM23_HUMAN,tr|G3XAP0|G3XAP0_HUMAN,tr|G3V546|G3V546_HUMAN" 3 1564.9188 1.45 20965 22108 3 1564.917 522.6469 Probable RNA-binding protein 23 OS=Homo sapiens OX=9606 GN=RBM23 PE=1 SV=1 6 3681.7 - 4.11E+06 - - - -1.1783 - 2.929 0.473 - 381 1 2 0 -0.0018 15 0 0 0 3.51E+07 2.42E+07 - - - 6.6172 0.9998 221125_WJC_METTL3_EV_vs_WT_F02.22109.22109.2 0.000439 18-Oct K.C[160.03]NEIINWLDK[136.11].N "sp|P11142|HSP7C_HUMAN,tr|E9PNE6|E9PNE6_HUMAN,tr|A8K7Q2|A8K7Q2_HUMAN,tr|E9PKE3|E9PKE3_HUMAN,tr|E9PM13|E9PM13_HUMAN,tr|E9PS65|E9PS65_HUMAN" 6 1311.6373 0.14 20966 22109 2 1311.634721 656.8259 Heat shock cognate 71 kDa protein OS=Homo sapiens OX=9606 GN=HSPA8 PE=1 SV=1 4.37 3681.8 - 3.30E+06 - - - -1.9449 - 2.266 0.502 - 571.9 1 2 0 -0.0026 10 0 0 0 2.07E+07 1.52E+08 - - - 5.0313 1 221125_WJC_METTL3_EV_vs_WT_F02.22111.22111.2 2.44E-09 19/32 R.AVC[160.03]MLSNTTAVAEAWAR[166.11].L "sp|Q9BQE3|TBA1C_HUMAN,tr|A0A1W2PQM2|A0A1W2PQM2_HUMAN,tr|F5H5D3|F5H5D3_HUMAN" 3 1859.8898 0.52 20968 22111 2 1859.887355 930.9522 Tubulin alpha-1C chain OS=Homo sapiens OX=9606 GN=TUBA1C PE=1 SV=1 6.04 3682 - 2.40E+06 - - - -1.2925 - 3.368 0.651 - 924.8 1 2 0 -0.0024 17 0 0 0 1.29E+07 2.46E+07 - - - 6.834 0.9992 221125_WJC_METTL3_EV_vs_WT_F02.22112.22112.3 0.000793 Dec-40 K.GK[136.11]FDVQWIFVK[136.11].D sp|Q9BYJ9|YTHD1_HUMAN 1 1381.7729 1.17 20969 22112 3 1381.769827 461.5982 YTH domain-containing family protein 1 OS=Homo sapiens OX=9606 GN=YTHDF1 PE=1 SV=1 8.59 3682.1 - 2.16E+06 - - - -2.2297 - 2.175 0.411 - 263.1 1 2 1 -0.0031 11 0 0 0 1.67E+07 1.43E+07 - - - 5.3288 1 221125_WJC_METTL3_EV_vs_WT_F02.22113.22113.3 0.000223 13/44 R.GSDVIIMLVGNK[136.11].T "sp|P20340|RAB6A_HUMAN,sp|Q9NRW1|RAB6B_HUMAN,tr|J3KR73|J3KR73_HUMAN,tr|C9JU14|C9JU14_HUMAN" 4 1252.6941 1.09 20970 22113 3 1252.691703 418.572 Ras-related protein Rab-6A OS=Homo sapiens OX=9606 GN=RAB6A PE=1 SV=3 5.84 3682.3 - 1.92E+06 - - - -1.8807 - 2.882 0.499 - 379.4 1 2 0 -0.0024 12 0 0 0 1.33E+07 1.22E+07 - - - 7.0367 0.9999 221125_WJC_METTL3_EV_vs_WT_F02.22114.22114.3 1.73E-07 15/72 R.ILGDPEEESWSPSLTNLEK.V sp|Q9HC52|CBX8_HUMAN 1 2143.0321 999 20971 22114 3 2143.022805 715.3513 Chromobox protein homolog 8 OS=Homo sapiens OX=9606 GN=CBX8 PE=1 SV=3 3.91 3682.4 - 1.34E+06 - - - -4.335 - 2.731 0.603 - 241.7 1 2 0 -0.0093 19 0 0 0 9.58E+06 0.00E+00 - - - 7.7285 1 221125_WJC_METTL3_EV_vs_WT_F02.22117.22117.2 3.19E-08 17/36 R.ILGDPEEESWSPSLTNLEK.V sp|Q9HC52|CBX8_HUMAN 1 2143.0321 3.19 20974 22117 2 2143.030766 1072.5233 Chromobox protein homolog 8 OS=Homo sapiens OX=9606 GN=CBX8 PE=1 SV=3 3.91 3682.8 - 941932 - - - -0.6201 - 3.346 0.692 - 776.1 1 2 0 -0.0013 19 0 0 0 9.71E+06 3.04E+06 - - - 7.121 1 221125_WJC_METTL3_EV_vs_WT_F02.22122.22122.3 7.16E-07 17/60 K.IASLPQEVQDVSLLEK.L "sp|Q9NQG5|RPR1B_HUMAN,tr|A2A2M0|A2A2M0_HUMAN" 2 1767.9618 2.47 20977 22122 3 1767.960397 590.3279 Regulation of nuclear pre-mRNA domain-containing protein 1B OS=Homo sapiens OX=9606 GN=RPRD1B PE=1 SV=1 4.14 3683.3 - 7.52E+06 - - - -0.8111 - 2.782 0.508 - 311.6 1 2 0 -0.0014 16 0 0 0 8.19E+07 3.31E+07 - - - 6.8286 1 221125_WJC_METTL3_EV_vs_WT_F02.22123.22123.3 3.04E-06 13/52 R.GLGWVQFSSEEGLR.N "sp|Q9GZT3|SLIRP_HUMAN,tr|H0YJW7|H0YJW7_HUMAN,tr|A0A087WUN7|A0A087WUN7_HUMAN,tr|G3V2S9|G3V2S9_HUMAN,tr|H0YJ40|H0YJ40_HUMAN,tr|G3V4X6|G3V4X6_HUMAN" 6 1563.7682 1.26 20978 22123 3 1563.767277 522.2633 "SRA stem-loop-interacting RNA-binding protein, mitochondrial OS=Homo sapiens OX=9606 GN=SLIRP PE=1 SV=1" 4.53 3683.3 - 4.11E+06 - - - -0.5627 - 2.38 0.503 - 254.8 1 2 0 -0.0009 14 0 0 0 3.07E+07 2.43E+07 - - - 6.4521 1 221125_WJC_METTL3_EV_vs_WT_F02.22125.22125.3 0.00219 13/52 R.GLGWVQFSSEEGLR[166.11].N "sp|Q9GZT3|SLIRP_HUMAN,tr|H0YJW7|H0YJW7_HUMAN,tr|A0A087WUN7|A0A087WUN7_HUMAN,tr|G3V2S9|G3V2S9_HUMAN,tr|H0YJ40|H0YJ40_HUMAN,tr|G3V4X6|G3V4X6_HUMAN" 6 1573.7764 1.26 20980 22125 3 1573.775881 525.5994 "SRA stem-loop-interacting RNA-binding protein, mitochondrial OS=Homo sapiens OX=9606 GN=SLIRP PE=1 SV=1" 4.53 3683.4 - 3.53E+06 - - - -0.3469 - 2.564 0.458 - 272.6 1 2 0 -0.0005 14 0 0 0 3.07E+07 2.43E+07 - - - 6.1483 1 221125_WJC_METTL3_EV_vs_WT_F02.22126.22126.2 2.86E-09 20-Dec K.TYSYLTPDLWK[136.11].E "sp|P15880|RS2_HUMAN,tr|E9PQD7|E9PQD7_HUMAN,tr|H0YEN5|H0YEN5_HUMAN" 3 1393.7009 0.98 20981 22126 2 1393.704367 697.8577 40S ribosomal protein S2 OS=Homo sapiens OX=9606 GN=RPS2 PE=1 SV=2 5.5 3683.5 - 3.22E+06 - - - 2.4747 - 2.196 0.644 - 350.8 1 2 0 0.0034 11 0 0 0 1.90E+08 1.94E+08 - - - 5.9245 0.9978 221125_WJC_METTL3_EV_vs_WT_F02.22127.22127.3 0.000553 16/60 K.IASLPQEVQDVSLLEK[136.11].L "sp|Q9NQG5|RPR1B_HUMAN,tr|A2A2M0|A2A2M0_HUMAN" 2 1775.976 2.47 20982 22127 3 1775.974031 592.9993 Regulation of nuclear pre-mRNA domain-containing protein 1B OS=Homo sapiens OX=9606 GN=RPRD1B PE=1 SV=1 4.14 3683.6 - 2.65E+06 - - - -1.1261 - 2.534 0.169 - 185.7 1 2 0 -0.002 16 0 0 0 8.31E+07 3.37E+07 - - - 2.8094 0.9998 221125_WJC_METTL3_EV_vs_WT_F02.22128.22128.2 1.71E-05 20-Dec K.TYSYLTPDLWK.E "sp|P15880|RS2_HUMAN,tr|E9PQD7|E9PQD7_HUMAN,tr|H0YEN5|H0YEN5_HUMAN" 3 1385.6867 0.98 20983 22128 2 1385.684649 693.8506 40S ribosomal protein S2 OS=Homo sapiens OX=9606 GN=RPS2 PE=1 SV=2 5.5 3683.7 - 2.55E+06 - - - -1.4931 - 2.357 0.445 - 369.6 1 2 0 -0.0021 11 0 0 0 1.90E+08 1.94E+08 - - - 4.6466 0.9999 221125_WJC_METTL3_EV_vs_WT_F02.22130.22130.2 1.04E-06 18/30 R.ALGEPITLFGEGPAER.R sp|O43172|PRP4_HUMAN 1 1655.8519 3.36 20985 22130 2 1655.850824 828.9332 U4\U6 small nuclear ribonucleoprotein Prp4 OS=Homo sapiens OX=9606 GN=PRPF4 PE=1 SV=2 4.25 3683.9 - 2.06E+06 - - - -0.6414 - 3.109 0.499 - 1048.4 1 2 0 -0.0011 16 0 0 0 4.29E+08 1.28E+08 - - - 5.515 1 221125_WJC_METTL3_EV_vs_WT_F02.22132.22132.2 2.82E-06 18-Nov K.C[160.03]NEIINWLDK.N "sp|P11142|HSP7C_HUMAN,tr|E9PNE6|E9PNE6_HUMAN,tr|A8K7Q2|A8K7Q2_HUMAN,tr|E9PKE3|E9PKE3_HUMAN,tr|E9PM13|E9PM13_HUMAN,tr|E9PS65|E9PS65_HUMAN" 6 1303.6231 0.14 20987 22132 2 1303.619238 652.8188 Heat shock cognate 71 kDa protein OS=Homo sapiens OX=9606 GN=HSPA8 PE=1 SV=1 4.37 3684.2 - 1.55E+06 - - - -2.941 - 2.422 0.574 - 710.2 1 2 0 -0.0038 10 0 0 0 2.07E+07 1.52E+08 - - - 5.7485 1 221125_WJC_METTL3_EV_vs_WT_F02.22134.22134.2 4.78E-09 17/36 R.LSVEEAVAAGVVGGEIQEK.L "sp|P58107|EPIPL_HUMAN,sp|P58107|EPIPL_HUMAN,sp|P58107|EPIPL_HUMAN,sp|P58107|EPIPL_HUMAN,sp|P58107|EPIPL_HUMAN,sp|P58107|EPIPL_HUMAN,tr|A0A075B730|A0A075B730_HUMAN,tr|A0A075B730|A0A075B730_HUMAN,tr|A0A075B730|A0A075B730_HUMAN,tr|A0A075B730|A0A075B730_HUMAN,tr|A0A075B730|A0A075B730_HUMAN,tr|A0A075B730|A0A075B730_HUMAN" 12 1883.984 1.68 20989 22134 2 1883.991606 942.9993 Epiplakin OS=Homo sapiens OX=9606 GN=EPPK1 PE=1 SV=3 4.09 3684.4 - 1.27E+06 - - - 4.025 - 3.156 0.589 - 718.1 1 2 0 0.0076 19 0 0 0 1.71E+07 1.02E+07 - - - 6.2146 0.9994 221125_WJC_METTL3_EV_vs_WT_F02.22135.22135.2 2.02E-05 24-Oct K.VLGTEDLYDYIDK.Y "sp|P68400|CSK21_HUMAN,tr|A0A2R8YFU2|A0A2R8YFU2_HUMAN,tr|A0A2R8YD58|A0A2R8YD58_HUMAN,tr|A0A2R8YF43|A0A2R8YF43_HUMAN,tr|A0A2R8Y5A0|A0A2R8Y5A0_HUMAN,tr|A0A2R8YDP2|A0A2R8YDP2_HUMAN,tr|E7EU96|E7EU96_HUMAN" 7 1542.7454 0.3 20990 22135 2 1542.741957 772.38 Casein kinase II subunit alpha OS=Homo sapiens OX=9606 GN=CSNK2A1 PE=1 SV=1 3.84 3684.6 - 1.16E+06 - - - -2.2026 - 1.997 0.424 - 248.9 1 2 0 -0.0034 13 0 0 0 1.01E+07 3.41E+07 - - - 3.9467 1 221125_WJC_METTL3_EV_vs_WT_F02.22136.22136.2 1.27E-08 16/32 K.VFPGSTTEDYNLIVIER.G "sp|Q13263|TIF1B_HUMAN,tr|M0R0K9|M0R0K9_HUMAN" 2 1951.9891 0.61 20991 22136 2 1951.989176 977.0018 Transcription intermediary factor 1-beta OS=Homo sapiens OX=9606 GN=TRIM28 PE=1 SV=5 4.14 3684.7 - 1.01E+06 - - - 0.0348 - 3.432 0.62 - 1037.2 1 2 0 0.0001 17 0 0 0 1.72E+07 2.82E+07 - - - 6.652 0.9997 221125_WJC_METTL3_EV_vs_WT_F02.22137.22137.2 1.40E-06 14/32 K.VVPSFLPVDQGGSLVGR[166.11].N sp|Q14126|DSG2_HUMAN 1 1735.9496 0.76 20992 22137 2 1735.946309 868.9821 Desmoglein-2 OS=Homo sapiens OX=9606 GN=DSG2 PE=1 SV=2 5.81 3684.8 - 923067 - - - -1.9188 - 2.244 0.5 - 343.1 1 2 0 -0.0033 17 0 0 0 5.13E+06 6.76E+06 - - - 4.7201 0.9999 221125_WJC_METTL3_EV_vs_WT_F02.22141.22141.2 1.89E-05 18-Oct K.FAAQELIEVK[136.11].R "sp|Q86U44|MTA70_HUMAN,tr|F5H6D8|F5H6D8_HUMAN,tr|H0YFV6|H0YFV6_HUMAN,tr|B4DTN4|B4DTN4_HUMAN" 4 1154.6427 0.1 20995 22141 2 1154.642048 578.3286 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 4.53 3685.3 - 1.25E+07 - - - -0.543 - 2.103 0.489 - 274.7 1 2 0 -0.0006 10 0 0 0 3.35E+07 3.39E+08 - - - 4.7275 1 221125_WJC_METTL3_EV_vs_WT_F02.22143.22143.2 1.59E-09 20-Dec K.YSFLQFDPAPR.R "sp|P67775|PP2AA_HUMAN,sp|P62714|PP2AB_HUMAN,tr|H0YBN9|H0YBN9_HUMAN" 3 1339.6561 0.75 20997 22143 2 1339.655775 670.8353 Serine\threonine-protein phosphatase 2A catalytic subunit alpha isoform OS=Homo sapiens OX=9606 GN=PPP2CA PE=1 SV=1 5.84 3685.4 - 6.95E+06 - - - -0.2329 - 2.38 0.665 - 370.8 1 2 0 -0.0003 11 0 0 0 5.84E+07 7.77E+07 - - - 6.2983 1 221125_WJC_METTL3_EV_vs_WT_F02.22145.22145.3 6.00E-11 17/68 R.AAVPSGASTGIYEALELR[166.11].D "sp|P13929|ENOB_HUMAN,sp|P06733|ENOA_HUMAN,sp|P09104|ENOG_HUMAN,tr|E5RI09|E5RI09_HUMAN,tr|F5H0C8|F5H0C8_HUMAN,tr|A0A2R8Y6G6|A0A2R8Y6G6_HUMAN,tr|A0A2R8YEG5|A0A2R8YEG5_HUMAN,tr|K7ERS8|K7ERS8_HUMAN,tr|K7EM90|K7EM90_HUMAN,tr|E5RG95|E5RG95_HUMAN,tr|A0A2R8Y879|A0A2R8Y879_HUMAN,tr|A0A2R8Y798|A0A2R8Y798_HUMAN,tr|F5H1C3|F5H1C3_HUMAN,tr|E5RGZ4|E5RGZ4_HUMAN,tr|A0A2R8YEM5|A0A2R8YEM5_HUMAN,tr|K7EPM1|K7EPM1_HUMAN,tr|K7EKN2|K7EKN2_HUMAN" 17 1813.9449 1.66 20999 22145 3 1813.944385 605.6556 Beta-enolase OS=Homo sapiens OX=9606 GN=ENO3 PE=1 SV=5 4.53 3685.5 - 3.70E+06 - - - -0.3109 - 3.62 0.62 - 297.8 1 2 0 -0.0006 18 0 0 0 2.46E+08 1.48E+08 - - - 8.6557 0.9998 221125_WJC_METTL3_EV_vs_WT_F02.22146.22146.2 0.000213 15/30 K.LAVEALSSLDGDLAGR[166.11].Y "sp|P12277|KCRB_HUMAN,tr|G3V4N7|G3V4N7_HUMAN" 2 1595.8394 0.99 21000 22146 2 1595.836878 798.927 Creatine kinase B-type OS=Homo sapiens OX=9606 GN=CKB PE=1 SV=1 4.03 3685.6 - 2.92E+06 - - - -1.5935 - 2.86 0.486 - 856 1 2 0 -0.0025 16 0 0 0 3.57E+07 3.62E+07 - - - 5.2133 0.9999 221125_WJC_METTL3_EV_vs_WT_F02.22147.22147.2 5.45E-05 18/30 R.ALGEPITLFGEGPAER[166.11].R sp|O43172|PRP4_HUMAN 1 1665.8602 3.36 21001 22147 2 1665.858928 833.9374 U4\U6 small nuclear ribonucleoprotein Prp4 OS=Homo sapiens OX=9606 GN=PRPF4 PE=1 SV=2 4.25 3685.6 - 2.72E+06 - - - -0.7372 - 2.811 0.515 - 1101.2 1 2 0 -0.0012 16 0 0 0 4.29E+08 1.28E+08 - - - 5.3854 1 221125_WJC_METTL3_EV_vs_WT_F02.22150.22150.2 5.85E-07 16/28 K.TILTLTGVSTLGDVK.N "sp|A6NDG6|PGP_HUMAN,tr|H3BV17|H3BV17_HUMAN" 2 1516.8712 1.15 21004 22150 2 1516.87165 759.4429 Glycerol-3-phosphate phosphatase OS=Homo sapiens OX=9606 GN=PGP PE=1 SV=1 5.5 3685.9 - 1.80E+06 - - - 0.2802 - 2.957 0.578 - 732 1 2 0 0.0004 15 0 0 0 1.28E+07 1.11E+07 - - - 5.9755 0.9999 221125_WJC_METTL3_EV_vs_WT_F02.22151.22151.2 1.05E-07 15/28 K.TILTLTGVSTLGDVK[136.11].N "sp|A6NDG6|PGP_HUMAN,tr|H3BV17|H3BV17_HUMAN" 2 1524.8854 1.15 21005 22151 2 1524.88691 763.45 Glycerol-3-phosphate phosphatase OS=Homo sapiens OX=9606 GN=PGP PE=1 SV=1 5.5 3686.1 - 1.43E+06 - - - 0.9738 - 3.046 0.465 - 572.2 1 2 0 0.0015 15 0 0 0 1.28E+07 1.11E+07 - - - 5.2134 0.9997 221125_WJC_METTL3_EV_vs_WT_F02.22152.22152.2 8.58E-05 13/20 R.YLQSLLAEVER.R "sp|O95232|LC7L3_HUMAN,tr|U3KQT3|U3KQT3_HUMAN,tr|J3KPP4|J3KPP4_HUMAN,tr|D6RHH0|D6RHH0_HUMAN,tr|D6RDI2|D6RDI2_HUMAN" 5 1319.7085 1.86 21006 22152 2 1319.708848 660.8615 Luc7-like protein 3 OS=Homo sapiens OX=9606 GN=LUC7L3 PE=1 SV=2 4.53 3686.2 - 1.42E+06 - - - 0.2516 - 2.448 0.313 - 531 1 2 0 0.0003 11 0 0 0 1.35E+07 7.24E+06 - - - 3.7746 0.9999 221125_WJC_METTL3_EV_vs_WT_F02.22153.22153.2 7.52E-06 13/22 K.LTVYTTLIDVTK.G "sp|Q13510|ASAH1_HUMAN,tr|A0A1B0GV06|A0A1B0GV06_HUMAN,tr|A0A1B0GUE3|A0A1B0GUE3_HUMAN,tr|A0A1B0GUH5|A0A1B0GUH5_HUMAN,tr|A0A1B0GUA4|A0A1B0GUA4_HUMAN,tr|A0A1B0GTM3|A0A1B0GTM3_HUMAN,tr|A0A1B0GW68|A0A1B0GW68_HUMAN,tr|A0A1B0GTZ5|A0A1B0GTZ5_HUMAN,tr|A0A1B0GUW4|A0A1B0GUW4_HUMAN,tr|E7EMM4|E7EMM4_HUMAN,tr|A0A1B0GTP7|A0A1B0GTP7_HUMAN,tr|A0A1B0GUG1|A0A1B0GUG1_HUMAN" 12 1365.7755 999 21007 22153 2 1365.775628 683.895 Acid ceramidase OS=Homo sapiens OX=9606 GN=ASAH1 PE=1 SV=5 5.83 3686.3 - 1.30E+06 - - - 0.0696 - 2.5 0.485 - 621.8 1 2 0 0.0001 12 0 0 0 9.20E+06 0.00E+00 - - - 5.0341 0.9995 221125_WJC_METTL3_EV_vs_WT_F02.22154.22154.2 2.74E-05 13/20 R.YLQSLLAEVER[166.11].R "sp|O95232|LC7L3_HUMAN,tr|U3KQT3|U3KQT3_HUMAN,tr|J3KPP4|J3KPP4_HUMAN,tr|D6RHH0|D6RHH0_HUMAN,tr|D6RDI2|D6RDI2_HUMAN" 5 1329.7168 1.86 21008 22154 2 1329.717984 665.8657 Luc7-like protein 3 OS=Homo sapiens OX=9606 GN=LUC7L3 PE=1 SV=2 4.53 3686.5 - 1.12E+06 - - - 0.9009 - 2.469 0.249 - 659.4 1 2 0 0.0012 11 0 0 0 1.35E+07 7.24E+06 - - - 3.3248 0.917 221125_WJC_METTL3_EV_vs_WT_F02.22155.22155.2 1.43E-05 16/24 F.PLIQAMHPTLAGK.L "sp|Q9H361|PABP3_HUMAN,sp|P11940|PABP1_HUMAN,tr|H0YAS6|H0YAS6_HUMAN,tr|H0YB75|H0YB75_HUMAN,tr|A0A7I2YQE4|A0A7I2YQE4_HUMAN,tr|A0A7I2V649|A0A7I2V649_HUMAN,tr|H0YAR2|H0YAR2_HUMAN,tr|E7ERJ7|E7ERJ7_HUMAN,tr|A0A7I2YQ88|A0A7I2YQ88_HUMAN,tr|A0A087WTT1|A0A087WTT1_HUMAN,tr|A0A7I2YQ90|A0A7I2YQ90_HUMAN,tr|A0A7I2V4N4|A0A7I2V4N4_HUMAN,tr|E7EQV3|E7EQV3_HUMAN" 13 1375.7646 1.11 21009 22155 2 1375.758151 688.8896 Polyadenylate-binding protein 3 OS=Homo sapiens OX=9606 GN=PABPC3 PE=1 SV=2 9.18 3686.6 - 1.02E+06 - - - -4.681 - 2.918 0.47 - 763.1 1 1 0 -0.0064 13 0 0 0 1.23E+07 1.11E+07 - - - 5.2589 0.9999 221125_WJC_METTL3_EV_vs_WT_F02.22162.22162.2 0.000373 17/30 K.LAVEALSSLDGDLAGR.Y "sp|P12277|KCRB_HUMAN,tr|G3V4N7|G3V4N7_HUMAN" 2 1585.8312 0.6 21015 22162 2 1585.831742 793.9229 Creatine kinase B-type OS=Homo sapiens OX=9606 GN=CKB PE=1 SV=1 4.03 3687.5 - 5.14E+06 - - - 0.3727 - 3.341 0.479 - 1012.4 1 2 0 0.0006 16 0 0 0 3.73E+07 6.26E+07 - - - 5.5444 1 221125_WJC_METTL3_EV_vs_WT_F02.22165.22165.2 2.87E-08 16/34 R.AAVPSGASTGIYEALELR.D "sp|P13929|ENOB_HUMAN,sp|P06733|ENOA_HUMAN,sp|P09104|ENOG_HUMAN,tr|E5RI09|E5RI09_HUMAN,tr|F5H0C8|F5H0C8_HUMAN,tr|A0A2R8Y6G6|A0A2R8Y6G6_HUMAN,tr|A0A2R8YEG5|A0A2R8YEG5_HUMAN,tr|K7ERS8|K7ERS8_HUMAN,tr|K7EM90|K7EM90_HUMAN,tr|E5RG95|E5RG95_HUMAN,tr|A0A2R8Y879|A0A2R8Y879_HUMAN,tr|A0A2R8Y798|A0A2R8Y798_HUMAN,tr|F5H1C3|F5H1C3_HUMAN,tr|E5RGZ4|E5RGZ4_HUMAN,tr|A0A2R8YEM5|A0A2R8YEM5_HUMAN,tr|K7EPM1|K7EPM1_HUMAN,tr|K7EKN2|K7EKN2_HUMAN" 17 1803.9367 1.58 21017 22165 2 1803.935031 902.9756 Beta-enolase OS=Homo sapiens OX=9606 GN=ENO3 PE=1 SV=5 4.53 3687.7 - 1.41E+07 - - - -0.9136 - 3.129 0.623 - 944.6 1 2 0 -0.0016 18 0 0 0 2.69E+08 1.70E+08 - - - 6.4465 1 221125_WJC_METTL3_EV_vs_WT_F02.22166.22166.2 5.42E-11 17/34 R.AAVPSGASTGIYEALELR[166.11].D "sp|P13929|ENOB_HUMAN,sp|P06733|ENOA_HUMAN,sp|P09104|ENOG_HUMAN,tr|E5RI09|E5RI09_HUMAN,tr|F5H0C8|F5H0C8_HUMAN,tr|A0A2R8Y6G6|A0A2R8Y6G6_HUMAN,tr|A0A2R8YEG5|A0A2R8YEG5_HUMAN,tr|K7ERS8|K7ERS8_HUMAN,tr|K7EM90|K7EM90_HUMAN,tr|E5RG95|E5RG95_HUMAN,tr|A0A2R8Y879|A0A2R8Y879_HUMAN,tr|A0A2R8Y798|A0A2R8Y798_HUMAN,tr|F5H1C3|F5H1C3_HUMAN,tr|E5RGZ4|E5RGZ4_HUMAN,tr|A0A2R8YEM5|A0A2R8YEM5_HUMAN,tr|K7EPM1|K7EPM1_HUMAN,tr|K7EKN2|K7EKN2_HUMAN" 17 1813.9449 1.58 21018 22166 2 1813.943667 907.9798 Beta-enolase OS=Homo sapiens OX=9606 GN=ENO3 PE=1 SV=5 4.53 3687.8 - 9.46E+06 - - - -0.7067 - 3.446 0.684 - 1094.2 1 2 0 -0.0013 18 0 0 0 2.69E+08 1.70E+08 - - - 7.1344 1 221125_WJC_METTL3_EV_vs_WT_F02.22168.22168.3 2.03E-08 16/68 R.LAGSLLTQALESHAEGFR.E "sp|Q13724|MOGS_HUMAN,tr|A0A3B3IS52|A0A3B3IS52_HUMAN,tr|A0A3B3IRK6|A0A3B3IRK6_HUMAN,tr|A0A3B3IRW2|A0A3B3IRW2_HUMAN" 4 1898.985 0.63 21020 22168 3 1898.988012 634.0023 Mannosyl-oligosaccharide glucosidase OS=Homo sapiens OX=9606 GN=MOGS PE=1 SV=5 5.4 3687.9 - 4.61E+06 - - - 1.5724 - 3.422 0.523 - 378 1 2 0 0.003 18 0 0 0 3.68E+07 5.82E+07 - - - 7.4335 1 221125_WJC_METTL3_EV_vs_WT_F02.22172.22172.3 2.27E-06 14/60 R.ALGEPITLFGEGPAER.R sp|O43172|PRP4_HUMAN 1 1655.8519 3.3 21024 22172 3 1655.851194 552.9579 U4\U6 small nuclear ribonucleoprotein Prp4 OS=Homo sapiens OX=9606 GN=PRPF4 PE=1 SV=2 4.25 3688.1 - 2.00E+06 - - - -0.4179 - 2.706 0.582 - 208.9 1 2 0 -0.0007 16 0 0 0 4.49E+07 1.36E+07 - - - 7.5828 0.9995 221125_WJC_METTL3_EV_vs_WT_F02.22175.22175.2 0.0309 16-Nov R.SEIDLFNIR[166.11].K "sp|P08758|ANXA5_HUMAN,tr|D6RBL5|D6RBL5_HUMAN,tr|D6RBE9|D6RBE9_HUMAN" 3 1115.585 0.97 21027 22175 2 1115.586673 558.7998 Annexin A5 OS=Homo sapiens OX=9606 GN=ANXA5 PE=1 SV=2 4.37 3688.4 - 1.34E+06 - - - 1.4602 - 2.204 0.311 - 431.6 1 2 0 0.0016 9 0 0 0 5.89E+06 6.07E+06 - - - 3.6238 0.9998 221125_WJC_METTL3_EV_vs_WT_F02.22177.22177.3 0.000431 16/80 R.GLTLAPGLSPAR[166.11]PLFGSDFEK[136.11].E sp|Q8IU81|I2BP1_HUMAN 1 2190.1804 1.49 21029 22177 3 2190.177927 731.0674 Interferon regulatory factor 2-binding protein 1 OS=Homo sapiens OX=9606 GN=IRF2BP1 PE=1 SV=1 6.07 3688.6 - 1.24E+06 - - - -1.1177 - 2.651 0.342 - 122.6 1 2 0 -0.0024 21 0 0 0 2.03E+07 1.36E+07 - - - 4.6897 1 221125_WJC_METTL3_EV_vs_WT_F02.22178.22178.2 5.17E-08 16/28 R.ANDTTFGLAAGVFTR.D sp|P49189|AL9A1_HUMAN 1 1539.7682 4.45 21030 22178 2 1539.763096 770.8914 4-trimethylaminobutyraldehyde dehydrogenase OS=Homo sapiens OX=9606 GN=ALDH9A1 PE=1 SV=3 5.88 3688.8 - 1.04E+06 - - - -3.2869 - 3.005 0.551 - 973.9 1 2 0 -0.0051 15 0 0 0 3.02E+07 6.77E+06 - - - 5.8142 1 221125_WJC_METTL3_EV_vs_WT_F02.22179.22179.3 7.36E-08 18/60 R.ALGEPITLFGEGPAER[166.11].R sp|O43172|PRP4_HUMAN 1 1665.8602 3.63 21031 22179 3 1665.861134 556.294 U4\U6 small nuclear ribonucleoprotein Prp4 OS=Homo sapiens OX=9606 GN=PRPF4 PE=1 SV=2 4.25 3688.9 - 1.01E+06 - - - 0.5871 - 2.842 0.502 - 351.5 1 2 0 0.001 16 0 0 0 4.29E+07 1.18E+07 - - - 6.8166 1 221125_WJC_METTL3_EV_vs_WT_F02.22181.22181.2 7.75E-10 16/32 R.IAEGFSDTALIMVDNTK.F "sp|O43402|EMC8_HUMAN,tr|M0R1B0|M0R1B0_HUMAN" 2 1823.8975 0.89 21033 22181 2 1823.892955 912.956 ER membrane protein complex subunit 8 OS=Homo sapiens OX=9606 GN=EMC8 PE=1 SV=1 4.03 3689.2 - 900359 - - - -2.5007 - 3.051 0.579 - 783.3 1 2 0 -0.0046 17 0 0 0 5.01E+06 5.66E+06 - - - 6.0585 0.9632 221125_WJC_METTL3_EV_vs_WT_F02.22183.22183.2 0.112 Oct-32 R.GLTVDSILQTDDATLGK[136.11].L "sp|P78549|NTH_HUMAN,tr|H3BRL9|H3BRL9_HUMAN,tr|A0A494BZZ6|A0A494BZZ6_HUMAN" 3 1753.9189 -1 21035 22183 2 1753.905558 877.9667 Endonuclease III-like protein 1 OS=Homo sapiens OX=9606 GN=NTHL1 PE=1 SV=2 3.93 3689.4 - 508239 - - - -7.6127 - 2.546 0.279 - 234.6 1 2 0 -0.0134 17 0 0 0 0.00E+00 0.00E+00 - - - 3.3951 0.9999 221125_WJC_METTL3_EV_vs_WT_F02.22185.22185.2 5.00E-07 13/24 K.C[160.03]EFQDAYVLLSEK[136.11].K "sp|P10809|CH60_HUMAN,tr|A0A7I2V2X6|A0A7I2V2X6_HUMAN,tr|A0A7I2YQK6|A0A7I2YQK6_HUMAN,tr|A0A7I2V599|A0A7I2V599_HUMAN,tr|A0A7I2YQ71|A0A7I2YQ71_HUMAN,tr|A0A7I2V5M1|A0A7I2V5M1_HUMAN,tr|A0A7I2V5K3|A0A7I2V5K3_HUMAN,tr|A0A7I2V369|A0A7I2V369_HUMAN" 8 1608.7585 0.92 21036 22185 2 1608.756601 805.3865 "60 kDa heat shock protein, mitochondrial OS=Homo sapiens OX=9606 GN=HSPD1 PE=1 SV=2" 4.14 3689.6 - 1.44E+06 - - - -1.1866 - 2.629 0.563 - 514 1 2 0 -0.0019 13 0 0 0 7.27E+06 7.88E+06 - - - 5.6795 1 221125_WJC_METTL3_EV_vs_WT_F02.22188.22188.2 6.64E-09 22/40 R.NVLLDPQLVPGGGASEMAVAH.A "sp|P49368|TCPG_HUMAN,tr|B4DUR8|B4DUR8_HUMAN" 2 2074.0517 - 21039 22188 2 2074.048468 1038.0331 T-complex protein 1 subunit gamma OS=Homo sapiens OX=9606 GN=CCT3 PE=1 SV=4 4.35 3689.9 - 1.73E+06 - - - -1.5704 - 3.621 0.633 - 986.9 1 1 0 -0.0033 21 0 0 0 - - - - - 6.8788 1 221125_WJC_METTL3_EV_vs_WT_F02.22190.22190.3 6.33E-09 17/72 R.VIDFDENTALDDAEEESFR.K "sp|Q14257|RCN2_HUMAN,tr|H0YL43|H0YL43_HUMAN" 2 2213.9601 1.2 21041 22190 3 2213.960946 738.994 Reticulocalbin-2 OS=Homo sapiens OX=9606 GN=RCN2 PE=1 SV=1 3.58 3690.2 - 1.63E+06 - - - 0.4038 - 3.047 0.609 - 421.8 1 2 0 0.0009 19 0 0 0 6.10E+06 5.08E+06 - - - 8.0668 0.9998 221125_WJC_METTL3_EV_vs_WT_F02.22192.22192.3 2.85E-05 17/68 K.VLPGDYEILATHPTWALK[136.11].E "sp|Q15155|NOMO1_HUMAN,sp|Q5JPE7|NOMO2_HUMAN,sp|P69849|NOMO3_HUMAN,tr|A0A7I2V686|A0A7I2V686_HUMAN,tr|A0A7I2V6B0|A0A7I2V6B0_HUMAN,tr|A0A7I2V4D7|A0A7I2V4D7_HUMAN,tr|A0A7I2V4T6|A0A7I2V4T6_HUMAN,tr|A0A0G2JP90|A0A0G2JP90_HUMAN,tr|A0A087X117|A0A087X117_HUMAN,tr|A0A7I2V2V8|A0A7I2V2V8_HUMAN,tr|A0A0G2JN29|A0A0G2JN29_HUMAN,tr|A0A7I2V2Z5|A0A7I2V2Z5_HUMAN,tr|A0A087WW46|A0A087WW46_HUMAN,tr|J3KN36|J3KN36_HUMAN" 14 2031.0921 1.61 21043 22192 3 2031.097706 678.038 Nodal modulator 1 OS=Homo sapiens OX=9606 GN=NOMO1 PE=1 SV=5 5.32 3690.4 - 1.52E+06 - - - 2.7783 - 2.689 0.442 - 279.5 1 2 0 0.0056 18 0 0 0 1.91E+07 1.19E+07 - - - 5.9294 0.9999 221125_WJC_METTL3_EV_vs_WT_F02.22195.22195.3 1.48E-05 15/44 R.IQVWLYEQVNMR.L sp|P62304|RUXE_HUMAN 1 1577.8024 0.07 21046 22195 3 1577.802425 526.9414 Small nuclear ribonucleoprotein E OS=Homo sapiens OX=9606 GN=SNRPE PE=1 SV=1 6 3690.7 - 1.22E+06 - - - -0.0057 - 2.521 0.405 - 310 1 2 0 0 12 0 0 0 6.67E+06 9.85E+07 - - - 5.6184 0.988 221125_WJC_METTL3_EV_vs_WT_F02.22197.22197.2 2.00E-06 13/24 R.SLVWGAEAVQALR.E "sp|Q9BSV6|SEN34_HUMAN,tr|A0A590UJ73|A0A590UJ73_HUMAN,tr|E7EQB3|E7EQB3_HUMAN,tr|A0A0G2JNK5|A0A0G2JNK5_HUMAN,tr|A0A0G2JNL0|A0A0G2JNL0_HUMAN,tr|A0A590UJW4|A0A590UJW4_HUMAN,tr|B0V3J0|B0V3J0_HUMAN" 7 1398.7619 1.58 21048 22197 2 1398.775672 700.3883 tRNA-splicing endonuclease subunit Sen34 OS=Homo sapiens OX=9606 GN=TSEN34 PE=1 SV=1 5.72 3690.8 - 1.15E+06 - - - 9.8108 - 2.672 0.507 - 562.7 1 2 0 0.0137 13 0 0 0 1.18E+07 7.48E+06 - - - 5.3038 0.9998 221125_WJC_METTL3_EV_vs_WT_F02.22203.22203.2 0.00028 13/20 K.LALDIEIATYR.K "sp|P14136|GFAP_HUMAN,sp|Q6KB66|K2C80_HUMAN,sp|P05787|K2C8_HUMAN,sp|P19013|K2C4_HUMAN,sp|P04264|K2C1_HUMAN,sp|P08729|K2C7_HUMAN,tr|A0A1W2PR46|A0A1W2PR46_HUMAN,tr|A0A1X7SBR3|A0A1X7SBR3_HUMAN,tr|A0A1W2PQU7|A0A1W2PQU7_HUMAN,tr|K7EJU1|K7EJU1_HUMAN,tr|A0A1X7SCE1|A0A1X7SCE1_HUMAN,tr|A0A1W2PRT3|A0A1W2PRT3_HUMAN,tr|A0A1W2PS58|A0A1W2PS58_HUMAN,tr|K7EPI4|K7EPI4_HUMAN" 14 1276.7027 93 21053 22203 2 1276.703627 639.3586 Glial fibrillary acidic protein OS=Homo sapiens OX=9606 GN=GFAP PE=1 SV=1 4.37 3691.5 - 1.46E+07 - - - 0.7237 - 2.768 0.382 - 894.5 1 2 0 0.0009 11 0 0 0 1.02E+08 1.10E+06 - - - 4.6164 1 221125_WJC_METTL3_EV_vs_WT_F02.22205.22205.3 4.15E-10 17/68 R.AAVPSGASTGIYEALELR.D "sp|P13929|ENOB_HUMAN,sp|P06733|ENOA_HUMAN,sp|P09104|ENOG_HUMAN,tr|E5RI09|E5RI09_HUMAN,tr|F5H0C8|F5H0C8_HUMAN,tr|A0A2R8Y6G6|A0A2R8Y6G6_HUMAN,tr|A0A2R8YEG5|A0A2R8YEG5_HUMAN,tr|K7ERS8|K7ERS8_HUMAN,tr|K7EM90|K7EM90_HUMAN,tr|E5RG95|E5RG95_HUMAN,tr|A0A2R8Y879|A0A2R8Y879_HUMAN,tr|A0A2R8Y798|A0A2R8Y798_HUMAN,tr|F5H1C3|F5H1C3_HUMAN,tr|E5RGZ4|E5RGZ4_HUMAN,tr|A0A2R8YEM5|A0A2R8YEM5_HUMAN,tr|K7EPM1|K7EPM1_HUMAN,tr|K7EKN2|K7EKN2_HUMAN" 17 1803.9367 1.66 21054 22205 3 1803.938859 602.3195 Beta-enolase OS=Homo sapiens OX=9606 GN=ENO3 PE=1 SV=5 4.53 3691.8 - 3.02E+07 - - - 1.2085 - 3.32 0.648 - 374.6 1 2 0 0.0022 18 0 0 0 2.46E+08 1.48E+08 - - - 8.752 1 221125_WJC_METTL3_EV_vs_WT_F02.22206.22206.2 6.08E-09 16/24 K.EVTWEVLEGEVEK.E sp|P05455|LA_HUMAN 1 1545.7563 0.75 21055 22206 2 1545.75624 773.8854 Lupus La protein OS=Homo sapiens OX=9606 GN=SSB PE=1 SV=2 3.98 3691.8 - 2.00E+06 - - - -0.0091 - 3.047 0.578 - 1040.5 1 2 0 0 13 0 0 0 1.41E+07 1.89E+07 - - - 6.1696 0.9998 221125_WJC_METTL3_EV_vs_WT_F02.22209.22209.2 6.38E-10 16/28 R.EGPVQFEEDPFGLDK.F "sp|Q13573|SNW1_HUMAN,tr|G3V4X8|G3V4X8_HUMAN" 2 1705.7835 1.98 21058 22209 2 1705.780528 853.899 SNW domain-containing protein 1 OS=Homo sapiens OX=9606 GN=SNW1 PE=1 SV=1 3.83 3692.2 - 1.33E+06 - - - -1.7611 - 2.674 0.503 - 695.9 1 2 0 -0.003 15 0 0 0 1.38E+07 6.99E+06 - - - 5.1734 1 221125_WJC_METTL3_EV_vs_WT_F02.22214.22214.2 1.61E-08 13/24 -.MFLQYYLNEQGDR[166.11].V "sp|Q9NPE3|NOP10_HUMAN,tr|H0YM60|H0YM60_HUMAN" 2 1685.7747 1.11 21063 22214 2 1685.775246 843.8946 H\ACA ribonucleoprotein complex subunit 3 OS=Homo sapiens OX=9606 GN=NOP10 PE=1 SV=1 4.37 3692.7 - 867656 - - - 0.3168 - 2.849 0.64 - 616.3 1 2 0 0.0005 13 0 0 0 1.23E+07 1.11E+07 - - - 6.4549 0.9481 221125_WJC_METTL3_EV_vs_WT_F02.22217.22217.3 0.12 Nov-68 R.ILESITVSSLMATPQDPK.G sp|Q9NQS7|INCE_HUMAN 1 1929.0129 1.4 21066 22217 3 1929.020628 644.0116 Inner centromere protein OS=Homo sapiens OX=9606 GN=INCENP PE=1 SV=3 4.37 3693.1 - 630403 - - - 4.0166 - 1.727 0.193 - 131 1 2 0 0.0077 18 0 0 0 5.00E+06 3.59E+06 - - - 2.0502 0.8927 221125_WJC_METTL3_EV_vs_WT_F02.22218.22218.2 0.0126 Oct-36 R.GLGGIGMGLGPGGQPISAS.Q "sp|Q9P2K5|MYEF2_HUMAN,tr|A0A0A0MR39|A0A0A0MR39_HUMAN,tr|A0A087WUT0|A0A087WUT0_HUMAN,tr|H0YN19|H0YN19_HUMAN,tr|A0A0A0MQW0|A0A0A0MQW0_HUMAN" 5 1624.8243 - 21067 22218 2 1624.826702 813.4194 Myelin expression factor 2 OS=Homo sapiens OX=9606 GN=MYEF2 PE=1 SV=3 5.52 3693.2 - 607579 - - - 1.4839 - 1.722 0.251 - 147.1 1 1 0 0.0024 19 0 0 0 - - - - - 2.2303 1 221125_WJC_METTL3_EV_vs_WT_F02.22219.22219.2 6.79E-17 18/36 R.LILPVGPAGGNQMLEQYDK.L "sp|P22061|PIMT_HUMAN,tr|F6S8N6|F6S8N6_HUMAN,tr|A0A3F2YNX8|A0A3F2YNX8_HUMAN,tr|A0A0A0MRJ6|A0A0A0MRJ6_HUMAN" 4 2042.0507 0.77 21068 22219 2 2042.047471 1022.0326 Protein-L-isoaspartate(D-aspartate) O-methyltransferase OS=Homo sapiens OX=9606 GN=PCMT1 PE=1 SV=4 4.37 3693.4 - 423845 - - - -1.5626 - 3.582 0.76 - 821.6 1 2 0 -0.0032 19 0 0 0 6.95E+06 9.06E+06 - - - 7.7903 1 221125_WJC_METTL3_EV_vs_WT_F02.22220.22220.2 2.73E-08 18/36 R.LILPVGPAGGNQMLEQYDK[136.11].L "sp|P22061|PIMT_HUMAN,tr|F6S8N6|F6S8N6_HUMAN,tr|A0A3F2YNX8|A0A3F2YNX8_HUMAN,tr|A0A0A0MRJ6|A0A0A0MRJ6_HUMAN" 4 2050.0649 0.77 21069 22220 2 2050.064686 1026.0397 Protein-L-isoaspartate(D-aspartate) O-methyltransferase OS=Homo sapiens OX=9606 GN=PCMT1 PE=1 SV=4 4.37 3693.5 - 366789 - - - -0.0859 - 3.58 0.721 - 771.3 1 2 0 -0.0002 19 0 0 0 6.95E+06 9.06E+06 - - - 7.5018 0.9976 221125_WJC_METTL3_EV_vs_WT_F02.22222.22222.3 0.00255 16/80 R.GLTLAPGLSPARPLFGSDFEK.E sp|Q8IU81|I2BP1_HUMAN 1 2172.1579 1.49 21070 22222 3 2172.163485 725.0599 Interferon regulatory factor 2-binding protein 1 OS=Homo sapiens OX=9606 GN=IRF2BP1 PE=1 SV=1 6.07 3693.7 - 1.39E+06 - - - 2.5689 - 2.558 0.238 - 171 1 2 0 0.0056 21 0 0 0 2.03E+07 1.36E+07 - - - 3.4437 1 221125_WJC_METTL3_EV_vs_WT_F02.22223.22223.2 3.46E-05 15/24 K.EVTWEVLEGEVEK[136.11].E sp|P05455|LA_HUMAN 1 1553.7705 0.75 21071 22223 2 1553.774787 777.8925 Lupus La protein OS=Homo sapiens OX=9606 GN=SSB PE=1 SV=2 3.98 3693.8 - 748163 - - - 2.7887 - 2.865 0.556 - 910.3 1 2 0 0.0043 13 0 0 0 1.41E+07 1.89E+07 - - - 5.8477 0.9992 221125_WJC_METTL3_EV_vs_WT_F02.22224.22224.2 0.00645 14-Aug R.DWVLNEFK[136.11].H "sp|P17844|DDX5_HUMAN,tr|A0A7I2V5F5|A0A7I2V5F5_HUMAN,tr|A0A7I2V507|A0A7I2V507_HUMAN,tr|J3KTA4|J3KTA4_HUMAN,tr|A0A0G2JLI4|A0A0G2JLI4_HUMAN,tr|A0A7I2V2S0|A0A7I2V2S0_HUMAN" 6 1057.5324 1.51 21072 22224 2 1057.533976 529.7735 Probable ATP-dependent RNA helicase DDX5 OS=Homo sapiens OX=9606 GN=DDX5 PE=1 SV=1 4.37 3693.9 - 6.37E+06 - - - 1.494 - 1.44 0.404 - 286.2 1 2 0 0.0016 8 0 0 0 2.91E+08 1.94E+08 - - - 3.1242 0.9999 221125_WJC_METTL3_EV_vs_WT_F02.22225.22225.2 8.58E-06 14/26 R.GFAFVTFESPADAK.A "sp|O75526|RMXL2_HUMAN,sp|Q96E39|RMXL1_HUMAN,sp|Q8N7X1|RMXL3_HUMAN,sp|P38159|RBMX_HUMAN,tr|A0A1B0GUK8|A0A1B0GUK8_HUMAN,tr|H3BT71|H3BT71_HUMAN,tr|H0Y6E7|H0Y6E7_HUMAN,tr|H3BR27|H3BR27_HUMAN" 8 1485.714 1.53 21073 22225 2 1485.714136 743.8643 "RNA-binding motif protein, X-linked-like-2 OS=Homo sapiens OX=9606 GN=RBMXL2 PE=1 SV=3" 4.37 3694 - 3.19E+06 - - - 0.0942 - 2.576 0.571 - 686.6 1 2 0 0.0001 14 0 0 0 9.99E+08 6.53E+08 - - - 5.6329 0.9998 221125_WJC_METTL3_EV_vs_WT_F02.22226.22226.2 0.00113 14/28 R.LTPSASLPPAQLLLR.A "sp|P06576|ATPB_HUMAN,tr|F8W079|F8W079_HUMAN,tr|F8W0P7|F8W0P7_HUMAN,tr|H0YH81|H0YH81_HUMAN" 4 1575.9348 3.45 21074 22226 2 1575.935655 788.9747 "ATP synthase subunit beta, mitochondrial OS=Homo sapiens OX=9606 GN=ATP5F1B PE=1 SV=3" 9.75 3694 - 2.53E+06 - - - 0.5248 - 2.301 0.471 - 276.1 1 2 0 0.0008 15 0 0 0 3.27E+07 9.48E+06 - - - 4.5684 0.9999 221125_WJC_METTL3_EV_vs_WT_F02.22228.22228.2 0.000589 13/24 R.DILVEADGAWVVK.M "sp|Q9Y2H1|ST38L_HUMAN,tr|F5H277|F5H277_HUMAN" 2 1413.7504 3.54 21076 22228 2 1413.748924 707.8825 Serine\threonine-protein kinase 38-like OS=Homo sapiens OX=9606 GN=STK38L PE=1 SV=3 4.03 3694.2 - 1.21E+06 - - - -1.0306 - 2.597 0.477 - 496 1 2 0 -0.0015 13 0 0 0 4.82E+07 1.36E+07 - - - 5.013 1 221125_WJC_METTL3_EV_vs_WT_F02.22230.22230.3 1.21E-05 Oct-48 -.MFLQYYLNEQGDR[166.11].V "sp|Q9NPE3|NOP10_HUMAN,tr|H0YM60|H0YM60_HUMAN" 2 1685.7747 1.01 21078 22230 3 1685.774676 562.9322 H\ACA ribonucleoprotein complex subunit 3 OS=Homo sapiens OX=9606 GN=NOP10 PE=1 SV=1 4.37 3694.4 - 1.07E+06 - - - -0.0214 - 2.181 0.506 - 97.5 1 2 0 0 13 0 0 0 7.44E+06 7.36E+06 - - - 6.2956 1 221125_WJC_METTL3_EV_vs_WT_F02.22231.22231.3 7.75E-07 21/48 R.TTNFAGILSQGLR[166.11].L "sp|P09874|PARP1_HUMAN,tr|A0A7I2V3E1|A0A7I2V3E1_HUMAN" 2 1386.7495 0.91 21079 22231 3 1386.749776 463.2571 Poly [ADP-ribose] polymerase 1 OS=Homo sapiens OX=9606 GN=PARP1 PE=1 SV=4 9.41 3694.5 - 1.02E+06 - - - 0.2113 - 2.997 0.486 - 618.1 1 2 0 0.0003 13 0 0 0 2.47E+07 2.72E+07 - - - 6.9343 0.9999 221125_WJC_METTL3_EV_vs_WT_F02.22232.22232.3 0.000694 16/48 R.TTNFAGILSQGLR.L "sp|P09874|PARP1_HUMAN,tr|A0A7I2V3E1|A0A7I2V3E1_HUMAN" 2 1376.7412 0.91 21080 22232 3 1376.741722 459.921 Poly [ADP-ribose] polymerase 1 OS=Homo sapiens OX=9606 GN=PARP1 PE=1 SV=4 9.41 3694.7 - 949340 - - - 0.3697 - 2.425 0.431 - 316.8 1 2 0 0.0005 13 0 0 0 2.47E+07 2.72E+07 - - - 5.7468 0.9999 221125_WJC_METTL3_EV_vs_WT_F02.22233.22233.3 1.01E-05 Nov-48 -.MFLQYYLNEQGDR.V "sp|Q9NPE3|NOP10_HUMAN,tr|H0YM60|H0YM60_HUMAN" 2 1675.7664 0.91 21081 22233 3 1675.768751 559.5961 H\ACA ribonucleoprotein complex subunit 3 OS=Homo sapiens OX=9606 GN=NOP10 PE=1 SV=1 4.37 3694.7 - 929770 - - - 1.3779 - 1.941 0.464 - 143.2 1 2 0 0.0023 13 0 0 0 7.55E+06 8.26E+06 - - - 5.5106 0.9979 221125_WJC_METTL3_EV_vs_WT_F02.22234.22234.2 0.052 24-Dec R.AIVFVVDSAAFQR.E "sp|Q9Y5M8|SRPRB_HUMAN,tr|H7C4H2|H7C4H2_HUMAN" 2 1421.7667 2.36 21082 22234 2 1421.766262 711.8906 Signal recognition particle receptor subunit beta OS=Homo sapiens OX=9606 GN=SRPRB PE=1 SV=3 5.88 3694.9 - 889811 - - - -0.3081 - 2.527 0.064 - 343 2 2 0 -0.0004 13 0 0 0 1.32E+07 5.60E+06 - - - 1.7584 0.9712 221125_WJC_METTL3_EV_vs_WT_F02.22238.22238.2 2.00E-08 14/30 R.LFVGNLPPDITEEEMR.K "sp|Q15233|NONO_HUMAN,tr|A0A7I2V535|A0A7I2V535_HUMAN,tr|A0A7I2V4N2|A0A7I2V4N2_HUMAN,tr|A0A7I2V4K9|A0A7I2V4K9_HUMAN,tr|A0A7I2V464|A0A7I2V464_HUMAN,tr|A0A7P0MRW0|A0A7P0MRW0_HUMAN,tr|C9IZL7|C9IZL7_HUMAN,tr|C9J4X2|C9J4X2_HUMAN,tr|A0A7I2YQK8|A0A7I2YQK8_HUMAN,tr|A0A7I2V4J2|A0A7I2V4J2_HUMAN,tr|A0A7I2V5Y7|A0A7I2V5Y7_HUMAN,tr|C9JYS8|C9JYS8_HUMAN" 12 1858.9135 0.86 21086 22238 2 1858.900536 930.464 Non-POU domain-containing octamer-binding protein OS=Homo sapiens OX=9606 GN=NONO PE=1 SV=4 4 3695.4 - 364055 - - - -6.974 - 2.626 0.251 - 376.3 1 2 0 -0.013 16 0 0 0 1.09E+07 1.27E+07 - - - 3.2644 0.9988 221125_WJC_METTL3_EV_vs_WT_F02.22241.22241.2 0.0412 14-Jul R.DWVLNEFK.H "sp|P17844|DDX5_HUMAN,tr|A0A7I2V5F5|A0A7I2V5F5_HUMAN,tr|A0A7I2V507|A0A7I2V507_HUMAN,tr|J3KTA4|J3KTA4_HUMAN,tr|A0A0G2JLI4|A0A0G2JLI4_HUMAN,tr|A0A7I2V2S0|A0A7I2V2S0_HUMAN" 6 1049.5182 1.51 21087 22241 2 1049.519009 525.7664 Probable ATP-dependent RNA helicase DDX5 OS=Homo sapiens OX=9606 GN=DDX5 PE=1 SV=1 4.37 3695.8 - 2.46E+07 - - - 0.7746 - 1.541 0.273 - 236.2 1 2 0 0.0008 8 0 0 0 2.91E+08 1.94E+08 - - - 2.3613 1 221125_WJC_METTL3_EV_vs_WT_F02.22242.22242.2 0.00049 13/24 R.TTNFAGILSQGLR[166.11].L "sp|P09874|PARP1_HUMAN,tr|A0A7I2V3E1|A0A7I2V3E1_HUMAN" 2 1386.7495 1.05 21088 22242 2 1386.75127 694.382 Poly [ADP-ribose] polymerase 1 OS=Homo sapiens OX=9606 GN=PARP1 PE=1 SV=4 9.41 3695.9 - 1.30E+07 - - - 1.2886 - 2.787 0.573 - 644.4 1 2 0 0.0018 13 0 0 0 1.59E+08 1.51E+08 - - - 5.9032 0.9997 221125_WJC_METTL3_EV_vs_WT_F02.22246.22246.3 6.84E-05 Nov-64 R.MLVTFDEELR[166.11]PLPVSVR[166.11].V sp|Q13200|PSMD2_HUMAN 1 2020.093 0.7 21092 22246 3 2020.098092 674.3716 26S proteasome non-ATPase regulatory subunit 2 OS=Homo sapiens OX=9606 GN=PSMD2 PE=1 SV=3 4.68 3696.1 - 1.96E+06 - - - 2.5093 - 2.26 0.393 - 126.7 1 2 0 0.0051 17 0 0 0 1.41E+07 2.00E+07 - - - 4.98 1 221125_WJC_METTL3_EV_vs_WT_F02.22249.22249.2 7.80E-06 24-Dec -.MFLQYYLNEQGDR.V "sp|Q9NPE3|NOP10_HUMAN,tr|H0YM60|H0YM60_HUMAN" 2 1675.7664 1.11 21095 22249 2 1675.767688 838.8905 H\ACA ribonucleoprotein complex subunit 3 OS=Homo sapiens OX=9606 GN=NOP10 PE=1 SV=1 4.37 3696.4 - 1.84E+06 - - - 0.7435 - 2.786 0.555 - 475.1 1 2 0 0.0012 13 0 0 0 1.23E+07 1.11E+07 - - - 5.7695 0.9999 221125_WJC_METTL3_EV_vs_WT_F02.22252.22252.3 1.48E-05 Dec-64 K.VFPGSTTEDYNLIVIER[166.11].G "sp|Q13263|TIF1B_HUMAN,tr|M0R0K9|M0R0K9_HUMAN" 2 1961.9974 0.74 21098 22252 3 1962.000715 655.0064 Transcription intermediary factor 1-beta OS=Homo sapiens OX=9606 GN=TRIM28 PE=1 SV=5 4.14 3696.7 - 1.33E+06 - - - 1.7008 - 2.447 0.5 - 153.5 1 2 0 0.0033 17 0 0 0 1.20E+07 1.64E+07 - - - 6.3743 0.9999 221125_WJC_METTL3_EV_vs_WT_F02.22255.22255.3 1.57E-05 Oct-64 K.VFPGSTTEDYNLIVIER.G "sp|Q13263|TIF1B_HUMAN,tr|M0R0K9|M0R0K9_HUMAN" 2 1951.9891 0.71 21101 22255 3 1951.991371 651.6703 Transcription intermediary factor 1-beta OS=Homo sapiens OX=9606 GN=TRIM28 PE=1 SV=5 4.14 3697.1 - 1.06E+06 - - - 1.1593 - 2.351 0.425 - 115.4 1 2 0 0.0023 17 0 0 0 9.80E+06 1.38E+07 - - - 5.4373 0.9992 221125_WJC_METTL3_EV_vs_WT_F02.22256.22256.2 0.000854 28-Oct R.LTPSASLPPAQLLLR[166.11].A "sp|P06576|ATPB_HUMAN,tr|F8W079|F8W079_HUMAN,tr|F8W0P7|F8W0P7_HUMAN,tr|H0YH81|H0YH81_HUMAN" 4 1585.9431 4.39 21102 22256 2 1585.939583 793.9788 "ATP synthase subunit beta, mitochondrial OS=Homo sapiens OX=9606 GN=ATP5F1B PE=1 SV=3" 9.75 3697.2 - 811740 - - - -2.2163 - 1.724 0.427 - 108.9 1 2 0 -0.0035 15 0 0 0 4.74E+07 1.08E+07 - - - 3.5328 0.9998 221125_WJC_METTL3_EV_vs_WT_F02.22259.22259.2 4.25E-06 14/32 K.VVDSLAPSITNVLVQGK[136.11].Q tr|I3L213|I3L213_HUMAN 1 1746.9971 1.8 21105 22259 2 1746.994621 874.5058 Phosphorylase b kinase regulatory subunit (Fragment) OS=Homo sapiens OX=9606 GN=PHKB PE=1 SV=1 5.81 3697.5 - 391338 - - - -1.419 - 2.147 0.464 - 283.6 1 2 0 -0.0025 17 0 0 0 3.49E+06 1.94E+06 - - - 4.3458 0.9999 221125_WJC_METTL3_EV_vs_WT_F02.22262.22262.2 5.54E-08 14/26 R.GFAFVTFESPADAK[136.11].A "sp|O75526|RMXL2_HUMAN,sp|Q96E39|RMXL1_HUMAN,sp|Q8N7X1|RMXL3_HUMAN,sp|P38159|RBMX_HUMAN,tr|A0A1B0GUK8|A0A1B0GUK8_HUMAN,tr|H3BT71|H3BT71_HUMAN,tr|H0Y6E7|H0Y6E7_HUMAN,tr|H3BR27|H3BR27_HUMAN" 8 1493.7282 1.56 21107 22262 2 1493.728492 747.8714 "RNA-binding motif protein, X-linked-like-2 OS=Homo sapiens OX=9606 GN=RBMXL2 PE=1 SV=3" 4.37 3697.9 - 1.41E+07 - - - 0.1982 - 2.593 0.571 - 668.4 1 2 0 0.0003 14 0 0 0 1.02E+09 6.53E+08 - - - 5.6494 1 221125_WJC_METTL3_EV_vs_WT_F02.22265.22265.3 0.00117 16/52 K.TIADLELHYQEFIR.N sp|P15924|DESP_HUMAN 1 1746.8941 1.82 21109 22265 3 1746.896157 583.3053 Desmoplakin OS=Homo sapiens OX=9606 GN=DSP PE=1 SV=3 4.65 3698.1 - 4.54E+06 - - - 1.1861 - 2.685 0.527 - 259.9 1 2 0 0.0021 14 0 0 0 1.33E+08 7.34E+07 - - - 7.0397 0.993 221125_WJC_METTL3_EV_vs_WT_F02.22270.22270.2 0.0426 22-Dec K.NGYGFVEFDDLR.D "sp|Q08170|SRSF4_HUMAN,tr|A0A0D9SEM4|A0A0D9SEM4_HUMAN" 2 1430.6466 6.26 21114 22270 2 1430.64087 716.3306 Serine\arginine-rich splicing factor 4 OS=Homo sapiens OX=9606 GN=SRSF4 PE=1 SV=2 4.03 3698.4 - 1.99E+06 - - - -4.0359 - 1.796 0.28 - 381.5 1 2 0 -0.0058 12 0 0 0 3.35E+07 5.35E+06 - - - 2.648 0.9993 221125_WJC_METTL3_EV_vs_WT_F02.22271.22271.2 0.00217 14-Aug R.DLFDFSTR.F "sp|Q9BV38|WDR18_HUMAN,tr|U3KQC1|U3KQC1_HUMAN,tr|A0A0A0MQU0|A0A0A0MQU0_HUMAN,tr|K7EIR0|K7EIR0_HUMAN" 4 999.4662 1.07 21115 22271 2 999.466943 500.7404 WD repeat-containing protein 18 OS=Homo sapiens OX=9606 GN=WDR18 PE=1 SV=2 4.21 3698.5 - 1.96E+06 - - - 0.7824 - 1.377 0.385 - 225.4 1 2 0 0.0008 8 0 0 0 1.30E+08 1.22E+08 - - - 2.8492 1 221125_WJC_METTL3_EV_vs_WT_F02.22273.22273.2 1.59E-07 18/28 K.LDGALGLSLEIGENR.L "sp|Q9NWS0|PIHD1_HUMAN,tr|M0QYA2|M0QYA2_HUMAN" 2 1555.8206 1.5 21117 22273 2 1555.820341 778.9176 PIH1 domain-containing protein 1 OS=Homo sapiens OX=9606 GN=PIH1D1 PE=1 SV=1 4.14 3698.7 - 1.79E+06 - - - -0.1575 - 3.496 0.544 - 1163 1 2 0 -0.0002 15 0 0 0 9.06E+07 6.05E+07 - - - 6.1361 0.9999 221125_WJC_METTL3_EV_vs_WT_F02.22274.22274.3 5.47E-05 13/68 K.FIIHAPPGEFNEVFNDVR.L "sp|P47755|CAZA2_HUMAN,tr|C9JUG7|C9JUG7_HUMAN,tr|A0A0D9SET8|A0A0D9SET8_HUMAN,tr|F8W9N7|F8W9N7_HUMAN" 4 2100.0429 2.36 21118 22274 3 2100.044731 701.0216 F-actin-capping protein subunit alpha-2 OS=Homo sapiens OX=9606 GN=CAPZA2 PE=1 SV=3 4.65 3698.8 - 1.53E+06 - - - 0.8838 - 2.279 0.426 - 209 1 2 0 0.0019 18 0 0 0 2.18E+07 9.25E+06 - - - 5.3402 1 221125_WJC_METTL3_EV_vs_WT_F02.22276.22276.2 2.97E-08 14/30 R.GITGVDLFGTTDAVVK[136.11].H "sp|P53621|COPA_HUMAN,tr|A0A3B3ISC6|A0A3B3ISC6_HUMAN,tr|A0A3B3ITV3|A0A3B3ITV3_HUMAN,tr|A0A3B3IU78|A0A3B3IU78_HUMAN,tr|A0A3B3IS84|A0A3B3IS84_HUMAN,tr|A0A3B3ISK1|A0A3B3ISK1_HUMAN,tr|A0A3B3IT15|A0A3B3IT15_HUMAN" 7 1599.8599 0.24 21120 22276 2 1599.858075 800.9372 Coatomer subunit alpha OS=Homo sapiens OX=9606 GN=COPA PE=1 SV=2 4.21 3698.9 - 1.23E+06 - - - -1.1645 - 3.03 0.55 - 594.6 1 2 0 -0.0019 16 0 0 0 2.08E+07 8.64E+07 - - - 5.8282 1 221125_WJC_METTL3_EV_vs_WT_F02.22278.22278.2 2.15E-10 15/30 R.FGPYYTEPVIAGLDPK.T "sp|P49720|PSB3_HUMAN,tr|A0A087WUL2|A0A087WUL2_HUMAN" 2 1765.8927 1.32 21122 22278 2 1765.893704 883.9536 Proteasome subunit beta type-3 OS=Homo sapiens OX=9606 GN=PSMB3 PE=1 SV=2 4.37 3699.2 - 1.15E+06 - - - 0.5753 - 2.568 0.649 - 526.5 1 2 0 0.001 16 0 0 0 2.54E+07 1.92E+07 - - - 6.1529 0.9999 221125_WJC_METTL3_EV_vs_WT_F02.22279.22279.2 1.05E-06 13/30 R.FGPYYTEPVIAGLDPK[136.11].T "sp|P49720|PSB3_HUMAN,tr|A0A087WUL2|A0A087WUL2_HUMAN" 2 1773.9069 1.32 21123 22279 2 1773.908143 887.9607 Proteasome subunit beta type-3 OS=Homo sapiens OX=9606 GN=PSMB3 PE=1 SV=2 4.37 3699.3 - 1.10E+06 - - - 0.7075 - 2.27 0.591 - 411 1 2 0 0.0013 16 0 0 0 2.54E+07 1.92E+07 - - - 5.4212 1 221125_WJC_METTL3_EV_vs_WT_F02.22280.22280.3 1.40E-09 17/52 R.QLPAMTALQTLHLR[166.11].S "sp|Q13045|FLII_HUMAN,tr|J3KS54|J3KS54_HUMAN,tr|J3QQU5|J3QQU5_HUMAN,tr|J3QQQ2|J3QQQ2_HUMAN,tr|J3QLR6|J3QLR6_HUMAN" 5 1601.8951 0.79 21124 22280 3 1601.895591 534.9723 Protein flightless-1 homolog OS=Homo sapiens OX=9606 GN=FLII PE=1 SV=2 9.76 3699.4 - 929978 - - - 0.3053 - 2.915 0.589 - 345.8 1 2 0 0.0005 14 0 0 0 9.71E+06 1.23E+07 - - - 7.9498 0.9984 221125_WJC_METTL3_EV_vs_WT_F02.22285.22285.2 0.0135 16-Aug K.EQGVLSFWR[166.11].G "sp|P05141|ADT2_HUMAN,sp|P12236|ADT3_HUMAN" 2 1130.5748 0.78 21128 22285 2 1130.575921 566.2947 ADP\ATP translocase 2 OS=Homo sapiens OX=9606 GN=SLC25A5 PE=1 SV=7 6.1 3700 - 1.40E+07 - - - 0.98 - 1.438 0.283 - 295.2 1 2 0 0.0011 9 0 0 0 8.82E+07 1.14E+08 - - - 2.1818 1 221125_WJC_METTL3_EV_vs_WT_F02.22286.22286.2 1.00E-10 14/30 R.AIYDFEAAEDNELTFK.A "sp|Q92783|STAM1_HUMAN,tr|A6NMU3|A6NMU3_HUMAN" 2 1874.8574 7 21129 22286 2 1874.854439 938.436 Signal transducing adapter molecule 1 OS=Homo sapiens OX=9606 GN=STAM PE=1 SV=3 3.83 3700.1 - 708408 - - - -1.5927 - 2.988 0.678 - 605.7 1 2 0 -0.003 16 0 0 0 5.31E+06 7.58E+05 - - - 6.7389 0.999 221125_WJC_METTL3_EV_vs_WT_F02.22287.22287.2 0.0515 14-Jul R.DLFDFSTR[166.11].F "sp|Q9BV38|WDR18_HUMAN,tr|U3KQC1|U3KQC1_HUMAN,tr|A0A0A0MQU0|A0A0A0MQU0_HUMAN,tr|K7EIR0|K7EIR0_HUMAN" 4 1009.4744 1.07 21130 22287 2 1009.475174 505.7445 WD repeat-containing protein 18 OS=Homo sapiens OX=9606 GN=WDR18 PE=1 SV=2 4.21 3700.2 - 6.74E+06 - - - 0.736 - 1.295 0.366 - 182 1 2 0 0.0007 8 0 0 0 1.30E+08 1.22E+08 - - - 2.5237 0.999 221125_WJC_METTL3_EV_vs_WT_F02.22291.22291.3 5.60E-09 25/88 A.ATAAAAAAAAAAVTAASTSYYGR.D "sp|Q9BWF3|RBM4_HUMAN,tr|E9PB51|E9PB51_HUMAN" 2 2057.0178 1.35 21134 22291 3 2057.017702 686.6799 RNA-binding protein 4 OS=Homo sapiens OX=9606 GN=RBM4 PE=1 SV=1 8.63 3700.4 - 1.65E+06 - - - -0.0389 - 4.626 0.565 - 968 1 1 0 -0.0001 23 0 0 0 1.70E+07 1.26E+07 - - - 8.4324 1 221125_WJC_METTL3_EV_vs_WT_F02.22292.22292.3 1.65E-05 Dec-48 R.NLANTVTEEILEK.A "sp|O60506|HNRPQ_HUMAN,tr|A0A7I2YQV8|A0A7I2YQV8_HUMAN,tr|A0A7I2YQN2|A0A7I2YQN2_HUMAN,tr|A0A7I2V4Z0|A0A7I2V4Z0_HUMAN,tr|B7Z645|B7Z645_HUMAN,tr|A0A7I2V2F2|A0A7I2V2F2_HUMAN,tr|A0A7I2V346|A0A7I2V346_HUMAN,tr|A0A7I2V309|A0A7I2V309_HUMAN" 8 1472.7722 1.44 21135 22292 3 1472.77104 491.9314 Heterogeneous nuclear ribonucleoprotein Q OS=Homo sapiens OX=9606 GN=SYNCRIP PE=1 SV=2 4.25 3700.5 - 1.63E+06 - - - -0.8141 - 2.555 0.46 - 317.2 1 2 0 -0.0012 13 0 0 0 6.03E+07 4.20E+07 - - - 6.2115 1 221125_WJC_METTL3_EV_vs_WT_F02.22293.22293.2 1.29E-10 18/28 F.SLDQPGGTLDLTLIR[166.11].A "sp|Q13263|TIF1B_HUMAN,tr|M0R0K9|M0R0K9_HUMAN" 2 1607.8758 0.35 21136 22293 2 1607.875919 804.9452 Transcription intermediary factor 1-beta OS=Homo sapiens OX=9606 GN=TRIM28 PE=1 SV=5 4.21 3700.6 - 1.32E+06 - - - 0.0703 - 3.403 0.584 - 888.5 1 1 0 0.0001 15 0 0 0 1.22E+07 3.44E+07 - - - 6.3653 0.9993 221125_WJC_METTL3_EV_vs_WT_F02.22294.22294.3 5.83E-05 14/48 R.IK[136.11]DYLLMEEEFIR[166.11].N sp|P62191|PRS4_HUMAN 1 1715.8923 0.46 21137 22294 3 1715.89855 572.9714 26S proteasome regulatory subunit 4 OS=Homo sapiens OX=9606 GN=PSMC1 PE=1 SV=1 4.41 3700.7 - 1.16E+06 - - - 3.6343 - 2.739 0.486 - 478.4 1 2 1 0.0062 13 0 0 0 9.93E+06 2.15E+07 - - - 6.6886 1 221125_WJC_METTL3_EV_vs_WT_F02.22295.22295.3 6.89E-05 Dec-48 R.NLANTVTEEILEK[136.11].A "sp|O60506|HNRPQ_HUMAN,tr|A0A7I2YQV8|A0A7I2YQV8_HUMAN,tr|A0A7I2YQN2|A0A7I2YQN2_HUMAN,tr|A0A7I2V4Z0|A0A7I2V4Z0_HUMAN,tr|B7Z645|B7Z645_HUMAN,tr|A0A7I2V2F2|A0A7I2V2F2_HUMAN,tr|A0A7I2V346|A0A7I2V346_HUMAN,tr|A0A7I2V309|A0A7I2V309_HUMAN" 8 1480.7864 1.37 21138 22295 3 1480.787258 494.6028 Heterogeneous nuclear ribonucleoprotein Q OS=Homo sapiens OX=9606 GN=SYNCRIP PE=1 SV=2 4.25 3700.8 - 1.06E+06 - - - 0.5531 - 2.53 0.446 - 318.7 1 2 0 0.0008 13 0 0 0 5.70E+07 4.16E+07 - - - 6.0289 0.9999 221125_WJC_METTL3_EV_vs_WT_F02.22296.22296.3 0.000104 Dec-44 R.FFHLAFEEEFGR.V "sp|Q13347|EIF3I_HUMAN,tr|A0A7I2YQT9|A0A7I2YQT9_HUMAN,tr|A0A7I2V613|A0A7I2V613_HUMAN,tr|A0A7I2V3N2|A0A7I2V3N2_HUMAN,tr|A0A7I2YQU2|A0A7I2YQU2_HUMAN,tr|A0A7I2YQF8|A0A7I2YQF8_HUMAN,tr|A0A7I2V3U3|A0A7I2V3U3_HUMAN,tr|A0A7I2V607|A0A7I2V607_HUMAN,tr|A0A7I2V640|A0A7I2V640_HUMAN,tr|A0A7P0MRT9|A0A7P0MRT9_HUMAN,tr|A0A7I2V5V8|A0A7I2V5V8_HUMAN,tr|A0A7I2V2M3|A0A7I2V2M3_HUMAN,tr|A0A7I2V4C2|A0A7I2V4C2_HUMAN,tr|A0A7I2YQI2|A0A7I2YQI2_HUMAN,tr|A0A7I2YQC8|A0A7I2YQC8_HUMAN,tr|A0A7I2V685|A0A7I2V685_HUMAN" 16 1527.7147 1.19 21139 22296 3 1527.717515 510.2455 Eukaryotic translation initiation factor 3 subunit I OS=Homo sapiens OX=9606 GN=EIF3I PE=1 SV=1 4.75 3700.9 - 1.05E+06 - - - 1.8662 - 2.671 0.44 - 168.7 1 2 0 0.0029 12 0 0 0 2.47E+07 2.08E+07 - - - 6.168 1 221125_WJC_METTL3_EV_vs_WT_F02.22297.22297.3 4.11E-09 18/56 K.LDGALGLSLEIGENR.L "sp|Q9NWS0|PIHD1_HUMAN,tr|M0QYA2|M0QYA2_HUMAN" 2 1555.8206 1.62 21140 22297 3 1555.823793 519.6141 PIH1 domain-containing protein 1 OS=Homo sapiens OX=9606 GN=PIH1D1 PE=1 SV=1 4.14 3701 - 954174 - - - 2.0613 - 2.979 0.499 - 463.9 1 2 0 0.0032 15 0 0 0 1.55E+07 9.59E+06 - - - 6.9508 1 221125_WJC_METTL3_EV_vs_WT_F02.22298.22298.2 3.80E-09 19/34 K.SPDLLMYQGPPDTAEIIK.T sp|P82909|RT36_HUMAN 1 1986.9972 2.79 21141 22298 2 1987.006011 994.5059 "28S ribosomal protein S36, mitochondrial OS=Homo sapiens OX=9606 GN=MRPS36 PE=1 SV=2" 4.03 3701.1 - 766578 - - - 4.4192 - 3.652 0.629 - 1127.2 1 2 0 0.0088 18 0 0 0 1.16E+07 4.16E+06 - - - 6.8685 1 221125_WJC_METTL3_EV_vs_WT_F02.22301.22301.2 9.72E-08 13/24 R.NLANTVTEEILEK.A "sp|O60506|HNRPQ_HUMAN,tr|A0A7I2YQV8|A0A7I2YQV8_HUMAN,tr|A0A7I2YQN2|A0A7I2YQN2_HUMAN,tr|A0A7I2V4Z0|A0A7I2V4Z0_HUMAN,tr|B7Z645|B7Z645_HUMAN,tr|A0A7I2V2F2|A0A7I2V2F2_HUMAN,tr|A0A7I2V346|A0A7I2V346_HUMAN,tr|A0A7I2V309|A0A7I2V309_HUMAN" 8 1472.7722 1.34 21142 22301 2 1472.773615 737.3934 Heterogeneous nuclear ribonucleoprotein Q OS=Homo sapiens OX=9606 GN=SYNCRIP PE=1 SV=2 4.25 3701.6 - 1.02E+07 - - - 0.9343 - 2.705 0.597 - 422.3 1 2 0 0.0014 13 0 0 0 2.44E+08 1.82E+08 - - - 6.004 0.9998 221125_WJC_METTL3_EV_vs_WT_F02.22303.22303.2 2.22E-06 13/24 R.NLANTVTEEILEK[136.11].A "sp|O60506|HNRPQ_HUMAN,tr|A0A7I2YQV8|A0A7I2YQV8_HUMAN,tr|A0A7I2YQN2|A0A7I2YQN2_HUMAN,tr|A0A7I2V4Z0|A0A7I2V4Z0_HUMAN,tr|B7Z645|B7Z645_HUMAN,tr|A0A7I2V2F2|A0A7I2V2F2_HUMAN,tr|A0A7I2V346|A0A7I2V346_HUMAN,tr|A0A7I2V309|A0A7I2V309_HUMAN" 8 1480.7864 1.34 21144 22303 2 1480.78858 741.4005 Heterogeneous nuclear ribonucleoprotein Q OS=Homo sapiens OX=9606 GN=SYNCRIP PE=1 SV=2 4.25 3701.6 - 7.94E+06 - - - 1.4459 - 2.715 0.477 - 431.1 1 2 0 0.0021 13 0 0 0 2.44E+08 1.82E+08 - - - 5.1269 0.9998 221125_WJC_METTL3_EV_vs_WT_F02.22304.22304.2 5.33E-06 22-Nov R.DIDPQNDLTFLR.L "sp|Q8TF09|DLRB2_HUMAN,sp|Q9NP97|DLRB1_HUMAN,tr|B1AKR6|B1AKR6_HUMAN,tr|H3BQI1|H3BQI1_HUMAN" 4 1445.7151 1.76 21145 22304 2 1445.71771 723.8648 Dynein light chain roadblock-type 2 OS=Homo sapiens OX=9606 GN=DYNLRB2 PE=1 SV=1 3.93 3701.7 - 4.87E+06 - - - 1.8344 - 2.411 0.558 - 389.5 1 2 0 0.0027 12 0 0 0 1.60E+08 9.08E+07 - - - 5.4771 0.9998 221125_WJC_METTL3_EV_vs_WT_F02.22305.22305.2 3.10E-06 15/28 K.LDGALGLSLEIGENR[166.11].L "sp|Q9NWS0|PIHD1_HUMAN,tr|M0QYA2|M0QYA2_HUMAN" 2 1565.8289 1.49 21146 22305 2 1565.832135 783.9217 PIH1 domain-containing protein 1 OS=Homo sapiens OX=9606 GN=PIH1D1 PE=1 SV=1 4.14 3701.7 - 4.17E+06 - - - 2.0941 - 3.074 0.472 - 787.6 1 2 0 0.0033 15 0 0 0 9.03E+07 6.05E+07 - - - 5.2871 0.9998 221125_WJC_METTL3_EV_vs_WT_F02.22306.22306.2 0.000565 20-Dec K.TVLELQYVLDK.L "sp|Q14444|CAPR1_HUMAN,tr|G3V153|G3V153_HUMAN,tr|E9PLA9|E9PLA9_HUMAN" 3 1319.7337 0.84 21147 22306 2 1319.735562 660.8741 Caprin-1 OS=Homo sapiens OX=9606 GN=CAPRIN1 PE=1 SV=2 4.37 3701.8 - 3.40E+06 - - - 1.4344 - 2.329 0.459 - 364.2 1 2 0 0.0019 11 0 0 0 6.12E+07 7.29E+07 - - - 4.7177 0.9964 221125_WJC_METTL3_EV_vs_WT_F02.22307.22307.2 4.05E-07 13/24 R.LDQELDFILSQQK.E "sp|P37198|NUP62_HUMAN,tr|M0QXN5|M0QXN5_HUMAN" 2 1575.8144 1.58 21148 22307 2 1575.823558 788.9145 Nuclear pore glycoprotein p62 OS=Homo sapiens OX=9606 GN=NUP62 PE=1 SV=3 4.03 3701.9 - 2.38E+06 - - - 5.7875 - 2.507 0.502 - 424.7 1 2 0 0.0091 13 0 0 0 1.99E+07 1.26E+07 - - - 5.1048 0.9999 221125_WJC_METTL3_EV_vs_WT_F02.22308.22308.2 5.32E-07 15/30 R.GITGVDLFGTTDAVVK.H "sp|P53621|COPA_HUMAN,tr|A0A3B3ISC6|A0A3B3ISC6_HUMAN,tr|A0A3B3ITV3|A0A3B3ITV3_HUMAN,tr|A0A3B3IU78|A0A3B3IU78_HUMAN,tr|A0A3B3IS84|A0A3B3IS84_HUMAN,tr|A0A3B3ISK1|A0A3B3ISK1_HUMAN,tr|A0A3B3IT15|A0A3B3IT15_HUMAN" 7 1591.8457 0.24 21149 22308 2 1591.846487 796.9301 Coatomer subunit alpha OS=Homo sapiens OX=9606 GN=COPA PE=1 SV=2 4.21 3701.9 - 1.82E+06 - - - 0.4705 - 2.593 0.517 - 501.4 1 2 0 0.0007 16 0 0 0 2.08E+07 8.64E+07 - - - 5.2019 0.9998 221125_WJC_METTL3_EV_vs_WT_F02.22310.22310.2 3.89E-08 17/28 K.SILNSLSGEELETLK[136.11].V "sp|Q9NRY5|F1142_HUMAN,tr|E7ESJ7|E7ESJ7_HUMAN" 2 1639.876 1.27 21151 22310 2 1639.879106 820.9453 Protein FAM114A2 OS=Homo sapiens OX=9606 GN=FAM114A2 PE=1 SV=4 4.25 3702.2 - 1.22E+06 - - - 1.905 - 3.052 0.496 - 820.2 1 2 0 0.0031 15 0 0 0 5.24E+07 4.13E+07 - - - 5.4467 1 221125_WJC_METTL3_EV_vs_WT_F02.22311.22311.2 2.87E-10 13/28 R.FC[160.03]NPGFPIGC[160.03]YITDK[136.11].G sp|Q99805|TM9S2_HUMAN 1 1795.8153 1.77 21152 22311 2 1795.819191 898.9149 Transmembrane 9 superfamily member 2 OS=Homo sapiens OX=9606 GN=TM9SF2 PE=1 SV=1 5.82 3702.3 - 909745 - - - 2.1589 - 2.657 0.641 - 422 1 2 0 0.0039 15 0 0 0 1.86E+07 1.05E+07 - - - 6.1767 0.9995 221125_WJC_METTL3_EV_vs_WT_F02.22312.22312.3 3.26E-05 13/56 K.LDGALGLSLEIGENR[166.11].L "sp|Q9NWS0|PIHD1_HUMAN,tr|M0QYA2|M0QYA2_HUMAN" 2 1565.8289 1.62 21153 22312 3 1565.8288 522.9502 PIH1 domain-containing protein 1 OS=Homo sapiens OX=9606 GN=PIH1D1 PE=1 SV=1 4.14 3702.4 - 891105 - - - -0.0358 - 2.402 0.268 - 192.4 1 2 0 -0.0001 15 0 0 0 1.55E+07 9.59E+06 - - - 3.8145 0.9999 221125_WJC_METTL3_EV_vs_WT_F02.22314.22314.2 0.00609 30-Dec R.LFVGNLPPDITEEEMR[166.11].K "sp|Q15233|NONO_HUMAN,tr|A0A7I2V535|A0A7I2V535_HUMAN,tr|A0A7I2V4N2|A0A7I2V4N2_HUMAN,tr|A0A7I2V4K9|A0A7I2V4K9_HUMAN,tr|A0A7I2V464|A0A7I2V464_HUMAN,tr|A0A7P0MRW0|A0A7P0MRW0_HUMAN,tr|C9IZL7|C9IZL7_HUMAN,tr|C9J4X2|C9J4X2_HUMAN,tr|A0A7I2YQK8|A0A7I2YQK8_HUMAN,tr|A0A7I2V4J2|A0A7I2V4J2_HUMAN,tr|A0A7I2V5Y7|A0A7I2V5Y7_HUMAN,tr|C9JYS8|C9JYS8_HUMAN" 12 1868.9218 1.17 21155 22314 2 1868.923196 935.4682 Non-POU domain-containing octamer-binding protein OS=Homo sapiens OX=9606 GN=NONO PE=1 SV=4 4 3702.6 - 509953 - - - 0.763 - 2.476 0.49 - 230.2 1 2 0 0.0014 16 0 0 0 6.43E+06 5.47E+06 - - - 4.8887 1 221125_WJC_METTL3_EV_vs_WT_F02.22319.22319.2 1.43E-09 17/30 R.VC[160.03]TLAIIDPGDSDIIR.S "sp|P62888|RL30_HUMAN,tr|E5RI99|E5RI99_HUMAN,tr|A0A0B4J213|A0A0B4J213_HUMAN,tr|A0A0C4DH44|A0A0C4DH44_HUMAN" 4 1756.9029 1.1 21158 22319 2 1756.902958 879.4587 60S ribosomal protein L30 OS=Homo sapiens OX=9606 GN=RPL30 PE=1 SV=2 3.93 3703.2 - 4.79E+06 - - - 0.0125 - 3.324 0.651 - 567.5 1 2 0 0 16 0 0 0 2.41E+08 2.20E+08 - - - 6.8024 1 221125_WJC_METTL3_EV_vs_WT_F02.22321.22321.3 4.44E-09 18/56 K.ALVTGYFMQVAHLER.T sp|O43143|DHX15_HUMAN 1 1733.8923 0.3 21160 22321 3 1733.894427 578.9714 Pre-mRNA-splicing factor ATP-dependent RNA helicase DHX15 OS=Homo sapiens OX=9606 GN=DHX15 PE=1 SV=2 6.79 3703.3 - 4.67E+06 - - - 1.2204 - 3.216 0.61 - 385.3 1 2 0 0.0021 15 0 0 0 3.74E+07 1.26E+08 - - - 8.3884 0.9999 221125_WJC_METTL3_EV_vs_WT_F02.22325.22325.3 2.18E-05 13/60 R.VC[160.03]TLAIIDPGDSDIIR[166.11].S "sp|P62888|RL30_HUMAN,tr|E5RI99|E5RI99_HUMAN,tr|A0A0B4J213|A0A0B4J213_HUMAN,tr|A0A0C4DH44|A0A0C4DH44_HUMAN" 4 1766.9112 1.15 21164 22325 3 1766.90772 589.9777 60S ribosomal protein L30 OS=Homo sapiens OX=9606 GN=RPL30 PE=1 SV=2 3.93 3703.5 - 2.07E+06 - - - -1.9729 - 2.848 0.48 - 269.6 1 2 0 -0.0035 16 0 0 0 8.37E+07 7.29E+07 - - - 6.576 0.9998 221125_WJC_METTL3_EV_vs_WT_F02.22326.22326.2 0.000642 24-Dec K.LTLDTIFVPNTGK[136.11].K "sp|Q9Y277|VDAC3_HUMAN,tr|E5RJN6|E5RJN6_HUMAN,tr|E5RK27|E5RK27_HUMAN,tr|E5RFP6|E5RFP6_HUMAN,tr|E5RHZ6|E5RHZ6_HUMAN" 5 1425.7959 1.37 21165 22326 2 1425.794847 713.9052 Voltage-dependent anion-selective channel protein 3 OS=Homo sapiens OX=9606 GN=VDAC3 PE=1 SV=1 5.84 3703.6 - 2.05E+06 - - - -0.7252 - 2.02 0.427 - 316.6 1 2 0 -0.001 13 0 0 0 5.82E+07 4.24E+07 - - - 3.999 0.9824 221125_WJC_METTL3_EV_vs_WT_F02.22327.22327.2 0.000131 20-Jul R.FEQLVNIGSSY.N "sp|Q8N5Z5|KCD17_HUMAN,tr|A0A087WX35|A0A087WX35_HUMAN,tr|H0Y731|H0Y731_HUMAN" 3 1255.6085 - 21166 22327 2 1255.608642 628.8115 BTB\POZ domain-containing protein KCTD17 OS=Homo sapiens OX=9606 GN=KCTD17 PE=1 SV=3 4 3703.7 - 1.96E+06 - - - 0.1386 - 1.672 0.428 - 175.2 1 1 0 0.0002 11 0 0 0 - - - - - 3.5927 1 221125_WJC_METTL3_EV_vs_WT_F02.22328.22328.2 7.51E-10 18/28 K.SPDTNYLFMGDYVDR[166.11].G "sp|P67775|PP2AA_HUMAN,sp|P62714|PP2AB_HUMAN,tr|E5RHC1|E5RHC1_HUMAN,tr|E7ESG8|E7ESG8_HUMAN,tr|E5RFI3|E5RFI3_HUMAN,tr|E5RHP4|E5RHP4_HUMAN" 6 1801.7857 0.42 21167 22328 2 1801.783577 901.9001 Serine\threonine-protein phosphatase 2A catalytic subunit alpha isoform OS=Homo sapiens OX=9606 GN=PPP2CA PE=1 SV=1 3.93 3703.8 - 1.66E+06 - - - -1.1622 - 3.601 0.708 - 1395.8 1 2 0 -0.0021 15 0 0 0 8.68E+06 2.05E+07 - - - 7.4195 0.9999 221125_WJC_METTL3_EV_vs_WT_F02.22329.22329.2 1.12E-05 13/28 R.FC[160.03]NPGFPIGC[160.03]YITDK.G sp|Q99805|TM9S2_HUMAN 1 1787.8011 1.77 21168 22329 2 1787.798744 894.9078 Transmembrane 9 superfamily member 2 OS=Homo sapiens OX=9606 GN=TM9SF2 PE=1 SV=1 5.82 3703.9 - 1.59E+06 - - - -1.3257 - 2.539 0.593 - 400.9 1 2 0 -0.0024 15 0 0 0 1.86E+07 1.05E+07 - - - 5.711 0.9296 221125_WJC_METTL3_EV_vs_WT_F02.22330.22330.2 0.000312 13/24 K.FPEVEDVVMVNVR.S "sp|P05198|IF2A_HUMAN,tr|G3V4T5|G3V4T5_HUMAN" 2 1531.7705 1.22 21169 22330 2 1531.779998 766.8925 Eukaryotic translation initiation factor 2 subunit 1 OS=Homo sapiens OX=9606 GN=EIF2S1 PE=1 SV=3 4.14 3704 - 1.27E+06 - - - 6.2235 - 2.282 0.105 - 355.2 1 2 0 0.0095 13 0 0 0 1.50E+07 1.23E+07 - - - 1.9311 1 221125_WJC_METTL3_EV_vs_WT_F02.22332.22332.3 6.97E-07 18/72 R.LLAELPASVHALTGVDLSK.L "sp|Q14254|FLOT2_HUMAN,tr|E7EMK3|E7EMK3_HUMAN,tr|J3QLD9|J3QLD9_HUMAN" 3 1933.0884 1.75 21171 22332 3 1933.089537 645.3701 Flotillin-2 OS=Homo sapiens OX=9606 GN=FLOT2 PE=1 SV=2 5.32 3704.2 - 622289 - - - 0.5737 - 3.449 0.55 - 291.5 1 2 0 0.0011 19 0 0 0 4.00E+07 2.28E+07 - - - 7.7134 0.9999 221125_WJC_METTL3_EV_vs_WT_F02.22334.22334.2 5.88E-06 13/20 K.TVLELQYVLDK[136.11].L "sp|Q14444|CAPR1_HUMAN,tr|G3V153|G3V153_HUMAN,tr|E9PLA9|E9PLA9_HUMAN" 3 1327.7479 0.84 21172 22334 2 1327.749368 664.8812 Caprin-1 OS=Homo sapiens OX=9606 GN=CAPRIN1 PE=1 SV=2 4.37 3704.4 - 7.84E+06 - - - 1.129 - 2.444 0.5 - 431.5 1 2 0 0.0015 11 0 0 0 6.12E+07 7.29E+07 - - - 5.151 0.9999 221125_WJC_METTL3_EV_vs_WT_F02.22336.22336.3 7.83E-08 13/60 R.VC[160.03]TLAIIDPGDSDIIR.S "sp|P62888|RL30_HUMAN,tr|E5RI99|E5RI99_HUMAN,tr|A0A0B4J213|A0A0B4J213_HUMAN,tr|A0A0C4DH44|A0A0C4DH44_HUMAN" 4 1756.9029 1.15 21173 22336 3 1756.904254 586.6416 60S ribosomal protein L30 OS=Homo sapiens OX=9606 GN=RPL30 PE=1 SV=2 3.93 3704.6 - 4.83E+06 - - - 0.7502 - 2.616 0.386 - 273.3 1 2 0 0.0013 16 0 0 0 8.37E+07 7.30E+07 - - - 5.3106 0.9991 221125_WJC_METTL3_EV_vs_WT_F02.22339.22339.3 0.00505 13/56 R.DLQGLTVEHAIDSFR.E sp|O43290|SNUT1_HUMAN 1 1699.8529 4.55 21176 22339 3 1699.854901 567.6249 U4\U6.U5 tri-snRNP-associated protein 1 OS=Homo sapiens OX=9606 GN=SART1 PE=1 SV=1 4.54 3704.8 - 2.13E+06 - - - 1.1483 - 2.012 0.281 - 173.6 1 2 0 0.002 15 0 0 0 1.64E+07 3.60E+06 - - - 3.4966 0.9996 221125_WJC_METTL3_EV_vs_WT_F02.22341.22341.2 0.00115 20-Dec R.TLVLLDNLNVR.E "sp|P39656|OST48_HUMAN,tr|U3KQ84|U3KQ84_HUMAN,tr|A0A0C4DGS1|A0A0C4DGS1_HUMAN" 3 1268.7452 1.29 21178 22341 2 1268.747088 635.3799 Dolichyl-diphosphooligosaccharide--protein glycosyltransferase 48 kDa subunit OS=Homo sapiens OX=9606 GN=DDOST PE=1 SV=4 5.5 3705 - 1.14E+06 - - - 1.4597 - 2.158 0.382 - 577 1 2 0 0.0019 11 0 0 0 2.24E+07 1.74E+07 - - - 3.9427 0.9995 221125_WJC_METTL3_EV_vs_WT_F02.22343.22343.3 0.00145 13/76 R.ELLTTMGDRFTDEEVDELYR.E "sp|O14950|ML12B_HUMAN,sp|P19105|ML12A_HUMAN,tr|J3QRS3|J3QRS3_HUMAN" 3 2431.1213 1.66 21180 22343 3 2431.123579 811.3811 Myosin regulatory light chain 12B OS=Homo sapiens OX=9606 GN=MYL12B PE=1 SV=2 3.95 3705.2 - 982913 - - - 0.9288 - 2.387 0.399 - 117.1 1 2 1 0.0023 20 0 0 0 2.00E+07 1.21E+07 - - - 5.0986 1 221125_WJC_METTL3_EV_vs_WT_F02.22345.22345.2 5.98E-12 21/38 K.EIILVDDYSNDPEDGALLGK.L sp|Q10471|GALT2_HUMAN 1 2175.0583 1.74 21182 22345 2 2175.063363 1088.5364 Polypeptide N-acetylgalactosaminyltransferase 2 OS=Homo sapiens OX=9606 GN=GALNT2 PE=1 SV=1 3.66 3705.5 - 880151 - - - 2.3232 - 3.637 0.721 - 1170.5 1 2 0 0.0051 20 0 0 0 5.34E+07 3.06E+07 - - - 7.5391 1 221125_WJC_METTL3_EV_vs_WT_F02.22351.22351.3 3.85E-09 18/72 R.YVQLPADEVDTQLLQDAAR.K sp|Q9Y333|LSM2_HUMAN 1 2144.075 2.87 21186 22351 3 2144.077805 715.6989 U6 snRNA-associated Sm-like protein LSm2 OS=Homo sapiens OX=9606 GN=LSM2 PE=1 SV=1 3.84 3706.2 - 5.08E+06 - - - 1.3255 - 3.396 0.615 - 389.9 1 2 0 0.0028 19 0 0 0 5.92E+07 2.06E+07 - - - 8.3995 1 221125_WJC_METTL3_EV_vs_WT_F02.22352.22352.3 3.23E-10 17/76 K.EIILVDDYSNDPEDGALLGK.L sp|Q10471|GALT2_HUMAN 1 2175.0583 2.08 21187 22352 3 2175.061884 726.0267 Polypeptide N-acetylgalactosaminyltransferase 2 OS=Homo sapiens OX=9606 GN=GALNT2 PE=1 SV=1 3.66 3706.3 - 4.74E+06 - - - 1.6432 - 3.509 0.646 - 333.1 1 2 0 0.0036 20 0 0 0 7.34E+07 3.53E+07 - - - 8.7867 0.9999 221125_WJC_METTL3_EV_vs_WT_F02.22353.22353.2 1.10E-05 13/20 R.FC[160.03]ADC[160.03]IITALR[166.11].S "sp|Q99496|RING2_HUMAN,tr|X6RFN3|X6RFN3_HUMAN" 2 1348.6507 1.19 21188 22353 2 1348.650592 675.3326 E3 ubiquitin-protein ligase RING2 OS=Homo sapiens OX=9606 GN=RNF2 PE=1 SV=1 5.82 3706.4 - 3.11E+06 - - - -0.0786 - 2.444 0.57 - 503.5 1 2 0 -0.0001 11 0 0 0 3.85E+07 3.23E+07 - - - 5.6685 1 221125_WJC_METTL3_EV_vs_WT_F02.22356.22356.2 1.38E-08 18/32 K.VALVTASTDGIGFAIAR[166.11].R "sp|Q6PKH6|DR4L2_HUMAN,sp|Q9BTZ2|DHRS4_HUMAN,tr|F5GWZ1|F5GWZ1_HUMAN,tr|F6TD35|F6TD35_HUMAN,tr|E9PFL3|E9PFL3_HUMAN" 5 1670.9231 1.47 21191 22356 2 1670.925818 836.4688 Dehydrogenase\reductase SDR family member 4-like 2 OS=Homo sapiens OX=9606 GN=DHRS4L2 PE=2 SV=2 5.81 3706.5 - 2.19E+06 - - - 1.632 - 3.542 0.512 - 1091.4 1 2 0 0.0027 17 0 0 0 2.72E+08 1.85E+08 - - - 5.9311 0.8274 221125_WJC_METTL3_EV_vs_WT_F02.22357.22357.2 0.0013 13/24 K.FPEVEDVVMVNVR[166.11].S "sp|P05198|IF2A_HUMAN,tr|G3V4T5|G3V4T5_HUMAN" 2 1541.7787 1.7 21192 22357 2 1541.787757 771.8966 Eukaryotic translation initiation factor 2 subunit 1 OS=Homo sapiens OX=9606 GN=EIF2S1 PE=1 SV=3 4.14 3706.6 - 2.19E+06 - - - 5.8517 - 2.122 0.003 - 464.4 1 2 0 0.009 13 0 0 0 1.50E+07 8.87E+06 - - - 0.9913 1 221125_WJC_METTL3_EV_vs_WT_F02.22359.22359.3 2.82E-05 Nov-44 R.FFHLAFEEEFGR[166.11].V "sp|Q13347|EIF3I_HUMAN,tr|A0A7I2YQT9|A0A7I2YQT9_HUMAN,tr|A0A7I2V613|A0A7I2V613_HUMAN,tr|A0A7I2V3N2|A0A7I2V3N2_HUMAN,tr|A0A7I2YQU2|A0A7I2YQU2_HUMAN,tr|A0A7I2YQF8|A0A7I2YQF8_HUMAN,tr|A0A7I2V3U3|A0A7I2V3U3_HUMAN,tr|A0A7I2V607|A0A7I2V607_HUMAN,tr|A0A7I2V640|A0A7I2V640_HUMAN,tr|A0A7P0MRT9|A0A7P0MRT9_HUMAN,tr|A0A7I2V5V8|A0A7I2V5V8_HUMAN,tr|A0A7I2V2M3|A0A7I2V2M3_HUMAN,tr|A0A7I2V4C2|A0A7I2V4C2_HUMAN,tr|A0A7I2YQI2|A0A7I2YQI2_HUMAN,tr|A0A7I2YQC8|A0A7I2YQC8_HUMAN,tr|A0A7I2V685|A0A7I2V685_HUMAN" 16 1537.7229 1.19 21194 22359 3 1537.721855 513.5816 Eukaryotic translation initiation factor 3 subunit I OS=Homo sapiens OX=9606 GN=EIF3I PE=1 SV=1 4.75 3706.8 - 1.57E+06 - - - -0.7017 - 2.192 0.506 - 135.7 1 2 0 -0.0011 12 0 0 0 2.47E+07 2.08E+07 - - - 6.3565 0.9998 221125_WJC_METTL3_EV_vs_WT_F02.22360.22360.2 0.0448 20-Dec K.FSLIDLAGNER[166.11].G "sp|O00139|KIF2A_HUMAN,tr|D6R9M0|D6R9M0_HUMAN,tr|A0A6Q8PFA6|A0A6Q8PFA6_HUMAN,tr|A0A6Q8PGH7|A0A6Q8PGH7_HUMAN,tr|A0A6Q8PG37|A0A6Q8PG37_HUMAN,tr|A0A6Q8PH57|A0A6Q8PH57_HUMAN" 6 1243.6436 1.09 21195 22360 2 1243.64386 622.8291 Kinesin-like protein KIF2A OS=Homo sapiens OX=9606 GN=KIF2A PE=1 SV=3 4.37 3706.9 - 1.46E+06 - - - 0.1922 - 2.319 0.406 - 437.6 1 2 0 0.0002 11 0 0 0 3.19E+07 2.93E+07 - - - 4.3151 1 221125_WJC_METTL3_EV_vs_WT_F02.22361.22361.3 1.06E-08 17/64 K.VALVTASTDGIGFAIAR.R "sp|Q6PKH6|DR4L2_HUMAN,sp|Q9BTZ2|DHRS4_HUMAN,tr|F5GWZ1|F5GWZ1_HUMAN,tr|F6TD35|F6TD35_HUMAN,tr|E9PFL3|E9PFL3_HUMAN" 5 1660.9148 1.49 21196 22361 3 1660.918544 554.6456 Dehydrogenase\reductase SDR family member 4-like 2 OS=Homo sapiens OX=9606 GN=DHRS4L2 PE=2 SV=2 5.81 3706.9 - 1.45E+06 - - - 2.2415 - 2.939 0.593 - 268.6 1 2 0 0.0037 17 0 0 0 1.42E+08 9.55E+07 - - - 7.8739 0.9352 221125_WJC_METTL3_EV_vs_WT_F02.22362.22362.3 1.52E-08 21/64 K.VFDEFKPLVEEPQNLIK.Q "sp|P02768|ALBU_HUMAN,tr|A0A087WWT3|A0A087WWT3_HUMAN,tr|B7WNR0|B7WNR0_HUMAN,tr|H0YA55|H0YA55_HUMAN,tr|A0A0C4DGB6|A0A0C4DGB6_HUMAN,tr|D6RHD5|D6RHD5_HUMAN,tr|C9JKR2|C9JKR2_HUMAN" 7 2044.0881 6.37 21197 22362 3 2045.107074 682.37 Albumin OS=Homo sapiens OX=9606 GN=ALB PE=1 SV=2 4.41 3707 - 1.37E+06 - - - 498.501 - 2.57 0.524 - 445.1 1 2 0 1.019 17 0 0 0 3.37E+07 5.29E+06 - - - 6.4844 1 221125_WJC_METTL3_EV_vs_WT_F02.22363.22363.3 4.05E-08 20/72 R.LLAELPASVHALTGVDLSK[136.11].L "sp|Q14254|FLOT2_HUMAN,tr|E7EMK3|E7EMK3_HUMAN,tr|J3QLD9|J3QLD9_HUMAN" 3 1941.1026 1.74 21198 22363 3 1941.103074 648.0415 Flotillin-2 OS=Homo sapiens OX=9606 GN=FLOT2 PE=1 SV=2 5.32 3707.1 - 1.34E+06 - - - 0.2298 - 3.521 0.604 - 369 1 2 0 0.0004 19 0 0 0 3.96E+07 2.28E+07 - - - 8.3664 0.9875 221125_WJC_METTL3_EV_vs_WT_F02.22367.22367.2 0.00309 13/20 R.WDDIADLVEAK[136.11].K "sp|O75449|KTNA1_HUMAN,tr|B7ZBC8|B7ZBC8_HUMAN" 2 1281.6332 0.63 21202 22367 2 1281.625442 641.8239 Katanin p60 ATPase-containing subunit A1 OS=Homo sapiens OX=9606 GN=KATNA1 PE=1 SV=1 3.84 3707.5 - 872622 - - - -6.079 - 1.844 0.386 - 396.7 1 2 0 -0.0078 11 0 0 0 7.09E+06 1.12E+07 - - - 3.545 0.9825 221125_WJC_METTL3_EV_vs_WT_F02.22370.22370.3 0.00505 Dec-52 R.LTLGEALQHPFFAR[166.11].L "sp|P49760|CLK2_HUMAN,tr|B1AVT0|B1AVT0_HUMAN" 2 1608.8652 0.78 21205 22370 3 1608.873834 537.2957 Dual specificity protein kinase CLK2 OS=Homo sapiens OX=9606 GN=CLK2 PE=1 SV=1 6.75 3707.9 - 550015 - - - 5.3777 - 2.169 0.256 - 162.6 1 2 0 0.0087 14 0 0 0 5.30E+06 6.81E+06 - - - 3.4494 1 221125_WJC_METTL3_EV_vs_WT_F02.22373.22373.2 4.86E-06 18-Dec R.DAVLLVFANK[136.11].Q "sp|P84077|ARF1_HUMAN,sp|P61204|ARF3_HUMAN,sp|P84085|ARF5_HUMAN,tr|F5H423|F5H423_HUMAN,tr|C9J1Z8|C9J1Z8_HUMAN" 5 1096.6372 1.15 21207 22373 2 1096.637895 549.3259 ADP-ribosylation factor 1 OS=Homo sapiens OX=9606 GN=ARF1 PE=1 SV=2 5.84 3708.2 - 3.05E+06 - - - 0.6374 - 2.498 0.579 - 676.6 1 2 0 0.0007 10 0 0 0 4.14E+07 3.62E+07 - - - 5.8727 1 221125_WJC_METTL3_EV_vs_WT_F02.22374.22374.2 3.61E-06 17/32 K.VALVTASTDGIGFAIAR.R "sp|Q6PKH6|DR4L2_HUMAN,sp|Q9BTZ2|DHRS4_HUMAN,tr|F5GWZ1|F5GWZ1_HUMAN,tr|F6TD35|F6TD35_HUMAN,tr|E9PFL3|E9PFL3_HUMAN" 5 1660.9148 1.47 21208 22374 2 1660.915836 831.4647 Dehydrogenase\reductase SDR family member 4-like 2 OS=Homo sapiens OX=9606 GN=DHRS4L2 PE=2 SV=2 5.81 3708.3 - 1.01E+07 - - - 0.6111 - 3.109 0.581 - 944.1 1 2 0 0.001 17 0 0 0 2.73E+08 1.86E+08 - - - 6.1207 1 221125_WJC_METTL3_EV_vs_WT_F02.22375.22375.3 4.39E-08 17/64 K.VALVTASTDGIGFAIAR[166.11].R "sp|Q6PKH6|DR4L2_HUMAN,sp|Q9BTZ2|DHRS4_HUMAN,tr|F5GWZ1|F5GWZ1_HUMAN,tr|F6TD35|F6TD35_HUMAN,tr|E9PFL3|E9PFL3_HUMAN" 5 1670.9231 1.49 21209 22375 3 1670.922706 557.9816 Dehydrogenase\reductase SDR family member 4-like 2 OS=Homo sapiens OX=9606 GN=DHRS4L2 PE=2 SV=2 5.81 3708.3 - 5.44E+06 - - - -0.2304 - 3.072 0.546 - 300.1 1 2 0 -0.0004 17 0 0 0 1.41E+08 9.46E+07 - - - 7.4626 1 221125_WJC_METTL3_EV_vs_WT_F02.22376.22376.2 1.07E-09 24-Dec K.TYTFDMVFGASTK.Q "sp|P52732|KIF11_HUMAN,tr|A0A7I2YQY4|A0A7I2YQY4_HUMAN,tr|A0A7I2V3V3|A0A7I2V3V3_HUMAN" 3 1466.6752 3.34 21210 22376 2 1466.679235 734.3449 Kinesin-like protein KIF11 OS=Homo sapiens OX=9606 GN=KIF11 PE=1 SV=2 5.5 3708.4 - 4.51E+06 - - - 2.7736 - 2.468 0.69 - 301.9 1 2 0 0.0041 13 0 0 0 7.68E+07 2.30E+07 - - - 6.4547 0.9997 221125_WJC_METTL3_EV_vs_WT_F02.22377.22377.2 0.295 20-Oct K.FSLIDLAGNER.G "sp|O00139|KIF2A_HUMAN,tr|D6R9M0|D6R9M0_HUMAN,tr|A0A6Q8PFA6|A0A6Q8PFA6_HUMAN,tr|A0A6Q8PGH7|A0A6Q8PGH7_HUMAN,tr|A0A6Q8PG37|A0A6Q8PG37_HUMAN,tr|A0A6Q8PH57|A0A6Q8PH57_HUMAN" 6 1233.6354 1.09 21211 22377 2 1233.636296 617.825 Kinesin-like protein KIF2A OS=Homo sapiens OX=9606 GN=KIF2A PE=1 SV=3 4.37 3708.4 - 4.01E+06 - - - 0.766 - 2.102 0.371 - 362.1 1 2 0 0.0009 11 0 0 0 3.19E+07 2.93E+07 - - - 3.7906 0.9989 221125_WJC_METTL3_EV_vs_WT_F02.22378.22378.2 0.00059 22-Sep R.IWIFDGPTGEGR[166.11].L "sp|Q8NI36|WDR36_HUMAN,tr|A0A0A0MTB8|A0A0A0MTB8_HUMAN" 2 1356.6702 0.95 21212 22378 2 1356.672873 679.3424 WD repeat-containing protein 36 OS=Homo sapiens OX=9606 GN=WDR36 PE=1 SV=1 4.37 3708.5 - 2.32E+06 - - - 1.9924 - 1.579 0.385 - 234.4 1 2 0 0.0027 12 0 0 0 2.27E+07 2.40E+07 - - - 3.0857 0.9999 221125_WJC_METTL3_EV_vs_WT_F02.22379.22379.3 0.00013 16/60 K.ALEPSFLPVAELHGLR.G "sp|Q14687|GSE1_HUMAN,tr|H0Y613|H0Y613_HUMAN" 2 1747.9621 2.17 21213 22379 3 1747.964637 583.6613 Genetic suppressor element 1 OS=Homo sapiens OX=9606 GN=GSE1 PE=1 SV=3 5.4 3708.5 - 2.15E+06 - - - 1.4485 - 2.514 0.452 - 284.2 1 2 0 0.0025 16 0 0 0 4.42E+07 2.04E+07 - - - 5.9441 1 221125_WJC_METTL3_EV_vs_WT_F02.22381.22381.2 8.62E-10 19/36 R.YVQLPADEVDTQLLQDAAR.K sp|Q9Y333|LSM2_HUMAN 1 2144.075 3.06 21215 22381 2 2144.076744 1073.0448 U6 snRNA-associated Sm-like protein LSm2 OS=Homo sapiens OX=9606 GN=LSM2 PE=1 SV=1 3.84 3708.8 - 1.88E+06 - - - 0.8307 - 3.568 0.655 - 759.5 1 2 0 0.0018 19 0 0 0 1.55E+07 5.07E+06 - - - 7.0056 0.9995 221125_WJC_METTL3_EV_vs_WT_F02.22384.22384.2 0.0293 20-Nov R.SLLQAVSELEK[136.11].K "sp|Q5TA31|RN187_HUMAN,tr|A0A1X7SBW3|A0A1X7SBW3_HUMAN" 2 1223.6853 3.89 21218 22384 2 1223.685565 612.8499 E3 ubiquitin-protein ligase RNF187 OS=Homo sapiens OX=9606 GN=RNF187 PE=1 SV=2 4.53 3709 - 1.25E+06 - - - 0.2427 - 2.163 0.271 - 381.3 1 2 0 0.0003 11 0 0 0 4.63E+07 1.19E+07 - - - 3.1296 1 221125_WJC_METTL3_EV_vs_WT_F02.22386.22386.2 5.96E-07 16/32 K.VFPGSTTEDYNLIVIER[166.11].G "sp|Q13263|TIF1B_HUMAN,tr|M0R0K9|M0R0K9_HUMAN" 2 1961.9974 0.83 21220 22386 2 1961.997634 982.006 Transcription intermediary factor 1-beta OS=Homo sapiens OX=9606 GN=TRIM28 PE=1 SV=5 4.14 3709.2 - 928357 - - - 0.1305 - 3.411 0.576 - 1018 1 2 0 0.0003 17 0 0 0 2.29E+07 2.76E+07 - - - 6.3119 0.9999 221125_WJC_METTL3_EV_vs_WT_F02.22387.22387.3 2.20E-07 20/68 K.VLLLIDDEYKVTAFPATR.N sp|Q8N766|EMC1_HUMAN 1 2063.1303 2.15 21221 22387 3 2063.124853 688.7174 ER membrane protein complex subunit 1 OS=Homo sapiens OX=9606 GN=EMC1 PE=1 SV=1 4.56 3709.4 - 886590 - - - -2.6368 - 4.013 0.561 - 514.2 1 2 1 -0.0054 18 0 0 0 1.11E+07 5.16E+06 - - - 8.2532 1 221125_WJC_METTL3_EV_vs_WT_F02.22388.22388.2 4.30E-13 15/36 R.YVQLPADEVDTQLLQDAAR[166.11].K sp|Q9Y333|LSM2_HUMAN 1 2154.0832 3.06 21222 22388 2 2154.087371 1078.0489 U6 snRNA-associated Sm-like protein LSm2 OS=Homo sapiens OX=9606 GN=LSM2 PE=1 SV=1 3.84 3709.5 - 749265 - - - 1.921 - 3.362 0.64 - 506.5 1 2 0 0.0041 19 0 0 0 1.55E+07 5.07E+06 - - - 6.7478 0.9996 221125_WJC_METTL3_EV_vs_WT_F02.22390.22390.2 1.55E-06 Nov-32 K.EFLPEGQDIGAFVAEQK[136.11].V "sp|Q04637|IF4G1_HUMAN,tr|H7C0V6|H7C0V6_HUMAN,tr|E7EUU4|E7EUU4_HUMAN,tr|E9PGM1|E9PGM1_HUMAN,tr|E7EX73|E7EX73_HUMAN,tr|A0A7I2Y1C3|A0A7I2Y1C3_HUMAN" 6 1884.9349 1.11 21224 22390 2 1884.939912 943.4747 Eukaryotic translation initiation factor 4 gamma 1 OS=Homo sapiens OX=9606 GN=EIF4G1 PE=1 SV=4 4 3709.7 - 492224 - - - 2.6622 - 2.509 0.534 - 250.9 1 2 0 0.005 17 0 0 0 3.89E+06 3.51E+06 - - - 5.2451 1 221125_WJC_METTL3_EV_vs_WT_F02.22393.22393.2 9.76E-11 15/24 K.YEEENFYLEPYLK[136.11].E sp|P14927|QCR7_HUMAN 1 1743.8123 2 21225 22393 2 1743.81361 872.9134 Cytochrome b-c1 complex subunit 7 OS=Homo sapiens OX=9606 GN=UQCRB PE=1 SV=2 4.09 3710.1 - 3.69E+06 - - - 0.7403 - 2.716 0.594 - 710.2 1 2 0 0.0013 13 0 0 0 5.44E+07 2.73E+07 - - - 5.9923 0.9998 221125_WJC_METTL3_EV_vs_WT_F02.22394.22394.2 3.95E-05 20-Nov R.SEDLLDYGPFR[166.11].D "sp|P04843|RPN1_HUMAN,tr|B7Z4L4|B7Z4L4_HUMAN" 2 1320.6226 1.32 21226 22394 2 1320.624705 661.3186 Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit 1 OS=Homo sapiens OX=9606 GN=RPN1 PE=1 SV=1 4.03 3710.2 - 2.95E+06 - - - 1.6303 - 2.272 0.528 - 491.1 1 2 0 0.0022 11 0 0 0 5.05E+07 3.81E+07 - - - 5.1602 1 221125_WJC_METTL3_EV_vs_WT_F02.22395.22395.2 2.11E-08 14/24 K.YEEENFYLEPYLK.E sp|P14927|QCR7_HUMAN 1 1735.7981 2.01 21227 22395 2 1735.799658 868.9063 Cytochrome b-c1 complex subunit 7 OS=Homo sapiens OX=9606 GN=UQCRB PE=1 SV=2 4.09 3710.2 - 6.99E+06 - - - 0.8866 - 2.771 0.673 - 601.4 1 2 0 0.0015 13 0 0 0 5.47E+07 2.73E+07 - - - 6.6271 0.9906 221125_WJC_METTL3_EV_vs_WT_F02.22397.22397.2 0.00118 24-Oct K.TNLVWDEVSGQWR[166.11].R sp|Q15050|RRS1_HUMAN 1 1598.7717 0.15 21229 22397 2 1599.774567 800.3931 Ribosome biogenesis regulatory protein homolog OS=Homo sapiens OX=9606 GN=RRS1 PE=1 SV=2 4.37 3710.3 - 2.47E+06 - - - 627.2884 - 1.957 0.467 - 304.1 1 2 0 1.0029 13 0 0 0 3.50E+06 2.35E+07 - - - 3.8986 0.9988 221125_WJC_METTL3_EV_vs_WT_F02.22400.22400.2 1.12E-07 14/32 R.YVLEPEISFTSDNSFAK[136.11].G sp|Q9NYU2|UGGG1_HUMAN 1 1953.9451 0.18 21232 22400 2 1953.940169 977.9798 UDP-glucose:glycoprotein glucosyltransferase 1 OS=Homo sapiens OX=9606 GN=UGGT1 PE=1 SV=3 4.14 3710.6 - 1.61E+06 - - - -2.5359 - 2.528 0.268 - 397.4 1 2 0 -0.005 17 0 0 0 2.62E+06 1.46E+07 - - - 3.299 0.9999 221125_WJC_METTL3_EV_vs_WT_F02.22402.22402.3 0.000943 Oct-48 K.TYTFDMVFGASTK.Q "sp|P52732|KIF11_HUMAN,tr|A0A7I2YQY4|A0A7I2YQY4_HUMAN,tr|A0A7I2V3V3|A0A7I2V3V3_HUMAN" 3 1466.6752 6.85 21234 22402 3 1466.676725 489.899 Kinesin-like protein KIF11 OS=Homo sapiens OX=9606 GN=KIF11 PE=1 SV=2 5.5 3710.8 - 1.16E+06 - - - 1.0623 - 1.768 0.459 - 98.2 1 2 0 0.0016 13 0 0 0 8.71E+06 1.27E+06 - - - 5.202 0.9981 221125_WJC_METTL3_EV_vs_WT_F02.22408.22408.2 2.48E-06 Dec-32 K.EFLPEGQDIGAFVAEQK.V "sp|Q04637|IF4G1_HUMAN,tr|H7C0V6|H7C0V6_HUMAN,tr|E7EUU4|E7EUU4_HUMAN,tr|E9PGM1|E9PGM1_HUMAN,tr|E7EX73|E7EX73_HUMAN,tr|A0A7I2Y1C3|A0A7I2Y1C3_HUMAN" 6 1876.9207 1.23 21240 22408 2 1876.929404 939.4676 Eukaryotic translation initiation factor 4 gamma 1 OS=Homo sapiens OX=9606 GN=EIF4G1 PE=1 SV=4 4 3711.6 - 525558 - - - 4.6406 - 2.062 0.546 - 347.7 1 2 0 0.0087 17 0 0 0 3.89E+06 3.16E+06 - - - 4.8502 0.9917 221125_WJC_METTL3_EV_vs_WT_F02.22410.22410.2 2.53E-06 Nov-34 L.LAATTEAPGEYFFSDGIR.L "sp|P12268|IMDH2_HUMAN,tr|A0A7I2YQK5|A0A7I2YQK5_HUMAN,tr|H0Y4R1|H0Y4R1_HUMAN,tr|A0A7I2V2T3|A0A7I2V2T3_HUMAN,tr|E7ETK5|E7ETK5_HUMAN" 5 1943.9265 0.2 21242 22410 2 1943.923372 972.9705 Inosine-5'-monophosphate dehydrogenase 2 OS=Homo sapiens OX=9606 GN=IMPDH2 PE=1 SV=2 4.14 3711.8 - 414161 - - - -1.6132 - 2.675 0.569 - 189.7 1 1 0 -0.0031 18 0 0 0 3.52E+06 1.75E+07 - - - 5.6617 0.98 221125_WJC_METTL3_EV_vs_WT_F02.22412.22412.3 0.00695 13/56 K.LK[136.11]VLGTAFDPFLGGK[136.11].N sp|Q92598|HS105_HUMAN 1 1577.9152 1.02 21244 22412 3 1577.909686 526.979 Heat shock protein 105 kDa OS=Homo sapiens OX=9606 GN=HSPH1 PE=1 SV=1 8.59 3712.1 - 346176 - - - -3.504 - 2.464 0.23 - 162.9 1 2 1 -0.0055 15 0 0 0 3.49E+06 3.43E+06 - - - 3.4558 0.9999 221125_WJC_METTL3_EV_vs_WT_F02.22414.22414.3 9.55E-05 Dec-44 K.LSGLVFFPHLDR[166.11].T sp|Q9Y2C4|EXOG_HUMAN 1 1409.7695 1.86 21245 22414 3 1409.770477 470.9304 "Nuclease EXOG, mitochondrial OS=Homo sapiens OX=9606 GN=EXOG PE=1 SV=2" 6.74 3712.4 - 261664 - - - 0.6994 - 2.275 0.397 - 246.2 1 2 0 0.001 12 0 0 0 5.23E+06 2.81E+06 - - - 5.2443 0.9998 221125_WJC_METTL3_EV_vs_WT_F02.22416.22416.2 0.00327 18-Oct K.MDMSLDDIIK[136.11].L "sp|Q86V81|THOC4_HUMAN,tr|E9PB61|E9PB61_HUMAN" 2 1187.5657 0.71 21246 22416 2 1187.567081 594.7901 THO complex subunit 4 OS=Homo sapiens OX=9606 GN=ALYREF PE=1 SV=3 3.93 3712.7 - 1.54E+07 - - - 1.1233 - 2.175 0.444 - 315.1 1 2 0 0.0013 10 0 0 0 3.07E+08 4.29E+08 - - - 4.4889 0.9997 221125_WJC_METTL3_EV_vs_WT_F02.22417.22417.2 6.61E-05 18-Sep K.MDMSLDDIIK.L "sp|Q86V81|THOC4_HUMAN,tr|E9PB61|E9PB61_HUMAN" 2 1179.5515 0.72 21247 22417 2 1179.553278 590.783 THO complex subunit 4 OS=Homo sapiens OX=9606 GN=ALYREF PE=1 SV=3 3.93 3712.7 - 8.61E+06 - - - 1.4675 - 2.046 0.467 - 250.9 1 2 0 0.0017 10 0 0 0 3.07E+08 4.29E+08 - - - 4.488 1 221125_WJC_METTL3_EV_vs_WT_F02.22420.22420.2 7.82E-08 20-Dec K.DSLTLVFVETK.K "sp|O00571|DDX3X_HUMAN,sp|O15523|DDX3Y_HUMAN,tr|A0A2R8YFR4|A0A2R8YFR4_HUMAN,tr|A0A2R8YCW1|A0A2R8YCW1_HUMAN,tr|A0A2R8YDH3|A0A2R8YDH3_HUMAN,tr|A0A2R8YDT5|A0A2R8YDT5_HUMAN,tr|A0A2R8Y645|A0A2R8Y645_HUMAN,tr|A0A2R8YF78|A0A2R8YF78_HUMAN,tr|A0A0D9SFB3|A0A0D9SFB3_HUMAN,tr|A0A2R8YFS5|A0A2R8YFS5_HUMAN,tr|A0A0D9SF53|A0A0D9SF53_HUMAN,tr|A0A0J9YVQ7|A0A0J9YVQ7_HUMAN,tr|A0A2R8Y5G6|A0A2R8Y5G6_HUMAN,tr|A0A2R8Y7T2|A0A2R8Y7T2_HUMAN,tr|A0A0D9SG12|A0A0D9SG12_HUMAN,tr|F6S8Q4|F6S8Q4_HUMAN,tr|A0A2U3TZJ9|A0A2U3TZJ9_HUMAN,tr|A0A2R8Y4A4|A0A2R8Y4A4_HUMAN" 18 1250.6758 1.28 21250 22420 2 1250.67718 626.3452 ATP-dependent RNA helicase DDX3X OS=Homo sapiens OX=9606 GN=DDX3X PE=1 SV=3 4.37 3712.8 - 5.65E+06 - - - 1.0882 - 2.621 0.555 - 919.8 1 2 0 0.0014 11 0 0 0 7.99E+07 6.25E+07 - - - 5.7464 0.9998 221125_WJC_METTL3_EV_vs_WT_F02.22421.22421.2 7.01E-06 20-Dec K.DSLTLVFVETK[136.11].K "sp|O00571|DDX3X_HUMAN,sp|O15523|DDX3Y_HUMAN,tr|A0A2R8YFR4|A0A2R8YFR4_HUMAN,tr|A0A2R8YCW1|A0A2R8YCW1_HUMAN,tr|A0A2R8YDH3|A0A2R8YDH3_HUMAN,tr|A0A2R8YDT5|A0A2R8YDT5_HUMAN,tr|A0A2R8Y645|A0A2R8Y645_HUMAN,tr|A0A2R8YF78|A0A2R8YF78_HUMAN,tr|A0A0D9SFB3|A0A0D9SFB3_HUMAN,tr|A0A2R8YFS5|A0A2R8YFS5_HUMAN,tr|A0A0D9SF53|A0A0D9SF53_HUMAN,tr|A0A0J9YVQ7|A0A0J9YVQ7_HUMAN,tr|A0A2R8Y5G6|A0A2R8Y5G6_HUMAN,tr|A0A2R8Y7T2|A0A2R8Y7T2_HUMAN,tr|A0A0D9SG12|A0A0D9SG12_HUMAN,tr|F6S8Q4|F6S8Q4_HUMAN,tr|A0A2U3TZJ9|A0A2U3TZJ9_HUMAN,tr|A0A2R8Y4A4|A0A2R8Y4A4_HUMAN" 18 1258.69 1.28 21251 22421 2 1258.692285 630.3523 ATP-dependent RNA helicase DDX3X OS=Homo sapiens OX=9606 GN=DDX3X PE=1 SV=3 4.37 3712.9 - 5.54E+06 - - - 1.8003 - 2.385 0.55 - 745.9 1 2 0 0.0023 11 0 0 0 7.99E+07 6.25E+07 - - - 5.454 1 221125_WJC_METTL3_EV_vs_WT_F02.22424.22424.3 8.26E-08 17/60 R.NALLQLTDSQIADVAR.F sp|O75643|U520_HUMAN 1 1726.9214 2.01 21254 22424 3 1726.924442 576.6477 U5 small nuclear ribonucleoprotein 200 kDa helicase OS=Homo sapiens OX=9606 GN=SNRNP200 PE=1 SV=2 4.21 3713 - 4.49E+06 - - - 1.7829 - 3.417 0.586 - 431.6 1 2 0 0.0031 16 0 0 0 3.25E+07 1.62E+07 - - - 8.2253 1 221125_WJC_METTL3_EV_vs_WT_F02.22426.22426.2 0.000305 18/30 R.NALLQLTDSQIADVAR.F sp|O75643|U520_HUMAN 1 1726.9214 2.01 21256 22426 2 1726.923062 864.468 U5 small nuclear ribonucleoprotein 200 kDa helicase OS=Homo sapiens OX=9606 GN=SNRNP200 PE=1 SV=2 4.21 3713.1 - 3.52E+06 - - - 0.9838 - 3.373 0.565 - 1013.1 1 2 0 0.0017 16 0 0 0 3.27E+07 1.63E+07 - - - 6.2027 1 221125_WJC_METTL3_EV_vs_WT_F02.22427.22427.3 1.00E-10 23/72 K.LGGSLADSYLDEGFLLDK[136.11]K[136.11].L "sp|P78371|TCPB_HUMAN,tr|F8VQ14|F8VQ14_HUMAN,tr|F5GWF6|F5GWF6_HUMAN" 3 2056.0699 0.51 21257 22427 3 2056.073184 686.3639 T-complex protein 1 subunit beta OS=Homo sapiens OX=9606 GN=CCT2 PE=1 SV=4 4.23 3713.2 - 3.02E+06 - - - 1.5787 - 4.74 0.653 - 952.7 1 2 0 0.0032 19 0 0 0 2.94E+08 5.78E+08 - - - 9.6423 0.9978 221125_WJC_METTL3_EV_vs_WT_F02.22429.22429.2 5.10E-09 15/30 K.GVLFGVPGAFTPGC[160.03]SK.T sp|P30044|PRDX5_HUMAN 1 1592.8021 1.62 21259 22429 2 1592.810669 797.4083 "Peroxiredoxin-5, mitochondrial OS=Homo sapiens OX=9606 GN=PRDX5 PE=1 SV=4" 8.22 3713.4 - 2.10E+06 - - - 5.3805 - 2.593 0.565 - 483.2 1 2 0 0.0086 16 0 0 0 3.70E+07 2.29E+07 - - - 5.5539 0.9046 221125_WJC_METTL3_EV_vs_WT_F02.22430.22430.2 0.00055 20-Oct K.SSGPTSLFAVT.V "sp|Q00839|HNRPU_HUMAN,tr|A0A1W2PP35|A0A1W2PP35_HUMAN,tr|A0A1W2PPS1|A0A1W2PPS1_HUMAN,tr|A0A1W2PP22|A0A1W2PP22_HUMAN,tr|A0A1X7SBS1|A0A1X7SBS1_HUMAN" 5 1065.5342 - 21260 22430 2 1065.536827 533.7744 Heterogeneous nuclear ribonucleoprotein U OS=Homo sapiens OX=9606 GN=HNRNPU PE=1 SV=6 5.24 3713.4 - 1.87E+06 - - - 2.4279 - 1.933 0.28 - 232.6 1 1 0 0.0026 11 0 0 0 - - - - - 2.8912 0.9998 221125_WJC_METTL3_EV_vs_WT_F02.22431.22431.2 0.000139 26-Nov R.IEEVPELPLVVEDK[136.11].V "sp|P36578|RL4_HUMAN,tr|H3BM89|H3BM89_HUMAN" 2 1615.88 1.83 21261 22431 2 1615.882005 808.9473 60S ribosomal protein L4 OS=Homo sapiens OX=9606 GN=RPL4 PE=1 SV=5 3.91 3713.5 - 1.32E+06 - - - 1.2377 - 2.169 0.456 - 361.5 1 2 0 0.002 14 0 0 0 4.18E+07 2.29E+07 - - - 4.3514 0.8989 221125_WJC_METTL3_EV_vs_WT_F02.22435.22435.2 0.0416 Oct-32 R.FSGLPSNDEPILSFSPK.T sp|O00443|P3C2A_HUMAN 1 1833.9149 1.77 21265 22435 2 1833.932364 917.9647 Phosphatidylinositol 4-phosphate 3-kinase C2 domain-containing subunit alpha OS=Homo sapiens OX=9606 GN=PIK3C2A PE=1 SV=2 4.37 3714 - 1.01E+06 - - - 9.5337 - 1.745 0.283 - 137 1 2 0 0.0175 17 0 0 0 2.45E+07 1.38E+07 - - - 2.4946 1 221125_WJC_METTL3_EV_vs_WT_F02.22439.22439.3 1.03E-07 19/80 R.SLSVLSSSTIIANPDIPEAYK.L "sp|P27694|RFA1_HUMAN,tr|I3L4R8|I3L4R8_HUMAN" 2 2204.1576 0.87 21268 22439 3 2204.160861 735.7265 Replication protein A 70 kDa DNA-binding subunit OS=Homo sapiens OX=9606 GN=RPA1 PE=1 SV=2 4.37 3714.4 - 7.89E+06 - - - 1.4659 - 2.838 0.555 - 316.7 1 2 0 0.0032 21 0 0 0 8.53E+07 9.85E+07 - - - 7.2276 1 221125_WJC_METTL3_EV_vs_WT_F02.22441.22441.3 1.41E-12 25/72 K.LGGSLADSYLDEGFLLDKK.L "sp|P78371|TCPB_HUMAN,tr|F8VQ14|F8VQ14_HUMAN,tr|F5GWF6|F5GWF6_HUMAN" 3 2040.0415 0.51 21270 22441 3 2040.043594 681.0211 T-complex protein 1 subunit beta OS=Homo sapiens OX=9606 GN=CCT2 PE=1 SV=4 4.23 3714.5 - 5.52E+06 - - - 1.0078 - 5.047 0.657 - 924.7 1 2 0 0.0021 19 0 0 0 2.94E+08 5.78E+08 - - - 9.8414 1 221125_WJC_METTL3_EV_vs_WT_F02.22442.22442.3 2.83E-05 16/60 R.NALLQLTDSQIADVAR[166.11].F sp|O75643|U520_HUMAN 1 1736.9296 2.01 21271 22442 3 1736.929525 579.9838 U5 small nuclear ribonucleoprotein 200 kDa helicase OS=Homo sapiens OX=9606 GN=SNRNP200 PE=1 SV=2 4.21 3714.5 - 3.97E+06 - - - -0.0622 - 3.156 0.487 - 381.4 1 2 0 -0.0001 16 0 0 0 3.25E+07 1.62E+07 - - - 6.9185 0.9999 221125_WJC_METTL3_EV_vs_WT_F02.22444.22444.2 9.40E-06 20-Nov K.NAAIAVLEELK.K "sp|O95793|STAU1_HUMAN,tr|Q5JW30|Q5JW30_HUMAN,tr|Q5JW28|Q5JW28_HUMAN" 3 1169.6656 1.86 21273 22444 2 1169.666172 585.8401 Double-stranded RNA-binding protein Staufen homolog 1 OS=Homo sapiens OX=9606 GN=STAU1 PE=1 SV=2 4.53 3714.6 - 3.19E+06 - - - 0.4984 - 2.226 0.48 - 433.3 1 2 0 0.0006 11 0 0 0 1.56E+07 8.40E+06 - - - 4.7508 1 221125_WJC_METTL3_EV_vs_WT_F02.22445.22445.3 4.25E-08 16/68 K.LFLNETQTQEITEDIPVK[136.11].T "sp|P41252|SYIC_HUMAN,tr|A0A804HL54|A0A804HL54_HUMAN,tr|A0A804HJN6|A0A804HJN6_HUMAN,tr|A0A804HHW9|A0A804HHW9_HUMAN" 4 2125.1034 -1 21274 22445 3 2125.102508 709.3751 "Isoleucine--tRNA ligase, cytoplasmic OS=Homo sapiens OX=9606 GN=IARS1 PE=1 SV=2" 4 3714.7 - 3.00E+06 - - - -0.4273 - 2.95 0.573 - 264.5 1 2 0 -0.0009 18 0 0 0 0.00E+00 0.00E+00 - - - 7.6219 0.9994 221125_WJC_METTL3_EV_vs_WT_F02.22446.22446.2 0.00043 30-Nov K.GVLFGVPGAFTPGC[160.03]SK[136.11].T sp|P30044|PRDX5_HUMAN 1 1600.8163 1.63 21275 22446 2 1600.819966 801.4154 "Peroxiredoxin-5, mitochondrial OS=Homo sapiens OX=9606 GN=PRDX5 PE=1 SV=4" 8.22 3714.7 - 2.42E+06 - - - 2.2907 - 1.882 0.455 - 266.3 1 2 0 0.0037 16 0 0 0 3.70E+07 2.27E+07 - - - 3.9551 1 221125_WJC_METTL3_EV_vs_WT_F02.22448.22448.2 1.76E-08 22/40 R.SLSVLSSSTIIANPDIPEAYK.L "sp|P27694|RFA1_HUMAN,tr|I3L4R8|I3L4R8_HUMAN" 2 2204.1576 1.28 21277 22448 2 2204.157985 1103.0861 Replication protein A 70 kDa DNA-binding subunit OS=Homo sapiens OX=9606 GN=RPA1 PE=1 SV=2 4.37 3715 - 1.90E+06 - - - 0.1611 - 3.54 0.595 - 761.6 1 2 0 0.0004 21 0 0 0 2.72E+07 2.13E+07 - - - 6.5435 1 221125_WJC_METTL3_EV_vs_WT_F02.22450.22450.2 7.28E-11 20/40 R.SLSVLSSSTIIANPDIPEAYK[136.11].L "sp|P27694|RFA1_HUMAN,tr|I3L4R8|I3L4R8_HUMAN" 2 2212.1718 1.28 21279 22450 2 2212.172905 1107.0932 Replication protein A 70 kDa DNA-binding subunit OS=Homo sapiens OX=9606 GN=RPA1 PE=1 SV=2 4.37 3715.2 - 1.33E+06 - - - 0.4859 - 3.609 0.653 - 652.8 1 2 0 0.0011 21 0 0 0 2.72E+07 2.13E+07 - - - 7.0191 1 221125_WJC_METTL3_EV_vs_WT_F02.22451.22451.2 8.66E-13 19/34 K.LFLNETQTQEITEDIPVK.T "sp|P41252|SYIC_HUMAN,tr|A0A804HL54|A0A804HL54_HUMAN,tr|A0A804HJN6|A0A804HJN6_HUMAN,tr|A0A804HHW9|A0A804HHW9_HUMAN" 4 2117.0892 0.9 21280 22451 2 2117.088782 1059.5519 "Isoleucine--tRNA ligase, cytoplasmic OS=Homo sapiens OX=9606 GN=IARS1 PE=1 SV=2" 4 3715.3 - 1.14E+06 - - - -0.205 - 3.937 0.664 - 930.7 1 2 0 -0.0004 18 0 0 0 1.19E+07 1.32E+07 - - - 7.3144 0.9982 221125_WJC_METTL3_EV_vs_WT_F02.22452.22452.2 0.0926 14-Aug K.QDILTIFK[136.11].R "sp|Q9NP61|ARFG3_HUMAN,tr|B0QYV8|B0QYV8_HUMAN" 2 984.5735 1.15 21281 22452 2 984.574687 493.294 ADP-ribosylation factor GTPase-activating protein 3 OS=Homo sapiens OX=9606 GN=ARFGAP3 PE=1 SV=1 5.84 3715.4 - 873502 - - - 1.1721 - 1.545 0.244 - 168.8 1 2 0 0.0012 8 0 0 0 6.66E+06 5.81E+06 - - - 2.1548 0.9994 221125_WJC_METTL3_EV_vs_WT_F02.22453.22453.2 5.63E-06 28-Dec R.LPLPSPALEYTLGSR[166.11].L sp|Q8IU81|I2BP1_HUMAN 1 1622.8907 1.25 21282 22453 2 1622.895164 812.4526 Interferon regulatory factor 2-binding protein 1 OS=Homo sapiens OX=9606 GN=IRF2BP1 PE=1 SV=1 6 3715.6 - 745066 - - - 2.7334 - 2.222 0.481 - 348.1 1 2 0 0.0044 15 0 0 0 9.52E+06 7.60E+06 - - - 4.5552 0.9999 221125_WJC_METTL3_EV_vs_WT_F02.22459.22459.2 0.00762 18/30 R.NALLQLTDSQIADVAR[166.11].F sp|O75643|U520_HUMAN 1 1736.9296 2.01 21287 22459 2 1736.928108 869.4721 U5 small nuclear ribonucleoprotein 200 kDa helicase OS=Homo sapiens OX=9606 GN=SNRNP200 PE=1 SV=2 4.21 3716.3 - 2.45E+06 - - - -0.878 - 3.348 0.498 - 1054.1 1 2 0 -0.0015 16 0 0 0 3.27E+07 1.63E+07 - - - 5.6896 1 221125_WJC_METTL3_EV_vs_WT_F02.22460.22460.3 1.05E-07 18/80 R.SLSVLSSSTIIANPDIPEAYK[136.11].L "sp|P27694|RFA1_HUMAN,tr|I3L4R8|I3L4R8_HUMAN" 2 2212.1718 1.16 21288 22460 3 2212.171915 738.3979 Replication protein A 70 kDa DNA-binding subunit OS=Homo sapiens OX=9606 GN=RPA1 PE=1 SV=2 4.37 3716.3 - 1.19E+07 - - - 0.0384 - 2.478 0.496 - 335.1 1 2 0 0.0001 21 0 0 0 8.41E+07 7.23E+07 - - - 6.2455 0.9998 221125_WJC_METTL3_EV_vs_WT_F02.22463.22463.2 1.76E-06 14/22 K.EVDNLYNIEILR.L sp|Q53HL2|BOREA_HUMAN 1 1489.7777 0.38 21291 22463 2 1489.780863 745.8961 Borealin OS=Homo sapiens OX=9606 GN=CDCA8 PE=1 SV=2 4.14 3716.4 - 9.83E+06 - - - 2.1507 - 2.629 0.534 - 627.8 1 2 0 0.0032 12 0 0 0 5.83E+07 1.52E+08 - - - 5.5274 0.9999 221125_WJC_METTL3_EV_vs_WT_F02.22464.22464.2 4.53E-06 19/30 R.ALIAGGGAPEIELALR[166.11].L sp|P50991|TCPD_HUMAN 1 1559.8911 0.39 21292 22464 2 1559.890223 780.9528 T-complex protein 1 subunit delta OS=Homo sapiens OX=9606 GN=CCT4 PE=1 SV=4 4.53 3716.5 - 4.92E+06 - - - -0.5379 - 3.063 0.477 - 1462.8 1 2 0 -0.0008 16 0 0 0 2.51E+07 6.45E+07 - - - 5.3159 1 221125_WJC_METTL3_EV_vs_WT_F02.22466.22466.2 2.59E-11 17/34 K.LFLNETQTQEITEDIPVK[136.11].T "sp|P41252|SYIC_HUMAN,tr|A0A804HL54|A0A804HL54_HUMAN,tr|A0A804HJN6|A0A804HJN6_HUMAN,tr|A0A804HHW9|A0A804HHW9_HUMAN" 4 2125.1034 0.9 21294 22466 2 2125.100897 1063.559 "Isoleucine--tRNA ligase, cytoplasmic OS=Homo sapiens OX=9606 GN=IARS1 PE=1 SV=2" 4 3716.6 - 3.07E+06 - - - -1.1854 - 3.57 0.65 - 616.1 1 2 0 -0.0025 18 0 0 0 1.19E+07 1.32E+07 - - - 6.9698 1 221125_WJC_METTL3_EV_vs_WT_F02.22467.22467.3 3.28E-06 15/60 R.SLHSELMC[160.03]PIC[160.03]LDMLK.N "sp|Q99496|RING2_HUMAN,sp|Q06587|RING1_HUMAN,tr|X6RFN3|X6RFN3_HUMAN" 3 1945.9134 1.27 21295 22467 3 1945.917644 649.6451 E3 ubiquitin-protein ligase RING2 OS=Homo sapiens OX=9606 GN=RNF2 PE=1 SV=1 5.3 3716.7 - 2.89E+06 - - - 2.1897 - 2.932 0.543 - 399.8 1 2 0 0.0043 16 0 0 0 1.45E+07 1.14E+07 - - - 7.3528 0.9999 221125_WJC_METTL3_EV_vs_WT_F02.22470.22470.2 0.000174 16/24 K.IQIEAIPLALQGR[166.11].D sp|Q9H0S4|DDX47_HUMAN 1 1430.8485 0.88 21298 22470 2 1430.848718 716.4315 Probable ATP-dependent RNA helicase DDX47 OS=Homo sapiens OX=9606 GN=DDX47 PE=1 SV=1 6 3716.9 - 2.17E+06 - - - 0.174 - 2.633 0.441 - 985.1 1 2 0 0.0002 13 0 0 0 1.62E+07 1.84E+07 - - - 4.7829 1 221125_WJC_METTL3_EV_vs_WT_F02.22471.22471.2 1.13E-06 20/30 R.ALIAGGGAPEIELALR.L sp|P50991|TCPD_HUMAN 1 1549.8828 0.39 21299 22471 2 1549.883019 775.9487 T-complex protein 1 subunit delta OS=Homo sapiens OX=9606 GN=CCT4 PE=1 SV=4 4.53 3717 - 1.94E+06 - - - 0.1465 - 3.24 0.518 - 1316.8 1 2 0 0.0002 16 0 0 0 2.49E+07 6.45E+07 - - - 5.7571 0.9996 221125_WJC_METTL3_EV_vs_WT_F02.22472.22472.2 0.131 14-Sep K.QDILTIFK.R "sp|Q9NP61|ARFG3_HUMAN,tr|B0QYV8|B0QYV8_HUMAN" 2 976.5593 1.12 21300 22472 2 976.559825 489.2869 ADP-ribosylation factor GTPase-activating protein 3 OS=Homo sapiens OX=9606 GN=ARFGAP3 PE=1 SV=1 5.84 3717.1 - 1.22E+06 - - - 0.5038 - 1.762 0.35 - 216.3 1 2 0 0.0005 8 0 0 0 6.66E+06 5.94E+06 - - - 3.3343 0.9984 221125_WJC_METTL3_EV_vs_WT_F02.22474.22474.3 0.46 Dec-48 K.IQIEAIPLALQGR[166.11].D sp|Q9H0S4|DDX47_HUMAN 1 1430.8485 0.73 21302 22474 3 1430.847127 477.9568 Probable ATP-dependent RNA helicase DDX47 OS=Homo sapiens OX=9606 GN=DDX47 PE=1 SV=1 6 3717.4 - 1.07E+06 - - - -0.9379 - 2.283 0.198 - 277.6 1 2 0 -0.0013 13 0 0 0 3.29E+06 4.47E+06 - - - 2.9853 0.9997 221125_WJC_METTL3_EV_vs_WT_F02.22475.22475.3 0.321 16/60 R.ALIAGGGAPEIELALR[166.11].L sp|P50991|TCPD_HUMAN 1 1559.8911 0.29 21303 22475 3 1559.89443 520.971 T-complex protein 1 subunit delta OS=Homo sapiens OX=9606 GN=CCT4 PE=1 SV=4 4.53 3717.5 - 1.01E+06 - - - 2.1591 - 2.821 0.32 - 447.5 1 2 0 0.0034 16 0 0 0 2.10E+06 7.23E+06 - - - 4.7678 1 221125_WJC_METTL3_EV_vs_WT_F02.22477.22477.2 1.69E-12 18/34 R.SAAEMYGSSFDLDYDFQR.D "tr|G3V251|G3V251_HUMAN,tr|B4DY08|B4DY08_HUMAN,tr|G3V3K6|G3V3K6_HUMAN,tr|B2R5W2|B2R5W2_HUMAN,tr|G3V4C1|G3V4C1_HUMAN,tr|G3V2D6|G3V2D6_HUMAN,tr|G3V5X6|G3V5X6_HUMAN,tr|G3V4W0|G3V4W0_HUMAN" 8 2100.8735 2.8 21305 22477 2 2100.876197 1051.444 Heterogeneous nuclear ribonucleoproteins C1\C2 (Fragment) OS=Homo sapiens OX=9606 GN=HNRNPC PE=1 SV=1 3.84 3717.7 - 945089 - - - 1.2904 - 3.733 0.773 - 1209.6 1 2 0 0.0027 18 0 0 0 6.06E+06 2.16E+06 - - - 7.988 1 221125_WJC_METTL3_EV_vs_WT_F02.22479.22479.3 0.000282 16/44 K.GSPIDVLHGLIR.R "tr|A0A669KAV7|A0A669KAV7_HUMAN,tr|M0QXA7|M0QXA7_HUMAN,tr|A0A669KBH9|A0A669KBH9_HUMAN" 3 1275.7299 1.36 21306 22479 3 1275.731795 426.2506 Protein Wiz OS=Homo sapiens OX=9606 GN=WIZ PE=1 SV=1 6.74 3717.9 - 1.15E+06 - - - 1.4697 - 2.83 0.445 - 614.3 1 2 0 0.0019 12 0 0 0 5.46E+06 4.00E+06 - - - 6.3843 0.9999 221125_WJC_METTL3_EV_vs_WT_F02.22480.22480.3 1.50E-05 14/44 K.GSPIDVLHGLIR[166.11].R "tr|A0A669KAV7|A0A669KAV7_HUMAN,tr|M0QXA7|M0QXA7_HUMAN,tr|A0A669KBH9|A0A669KBH9_HUMAN" 3 1285.7382 1.36 21307 22480 3 1285.739608 429.5867 Protein Wiz OS=Homo sapiens OX=9606 GN=WIZ PE=1 SV=1 6.74 3718.1 - 940265 - - - 1.1029 - 2.557 0.421 - 441.5 1 2 0 0.0014 12 0 0 0 5.46E+06 4.00E+06 - - - 5.8357 0.9999 221125_WJC_METTL3_EV_vs_WT_F02.22481.22481.3 1.10E-06 17/68 K.LFLNETQTQEITEDIPVK.T "sp|P41252|SYIC_HUMAN,tr|A0A804HL54|A0A804HL54_HUMAN,tr|A0A804HJN6|A0A804HJN6_HUMAN,tr|A0A804HHW9|A0A804HHW9_HUMAN" 4 2117.0892 1.11 21308 22481 3 2117.084101 706.7037 "Isoleucine--tRNA ligase, cytoplasmic OS=Homo sapiens OX=9606 GN=IARS1 PE=1 SV=2" 4 3718.1 - 4.24E+06 - - - -2.4161 - 2.738 0.477 - 303.4 1 2 0 -0.0051 18 0 0 0 1.03E+07 9.29E+06 - - - 6.3648 1 221125_WJC_METTL3_EV_vs_WT_F02.22482.22482.3 1.65E-06 17/64 R.TVLEHYALEDDPLAAFK[136.11].Q "sp|Q3ZCQ8|TIM50_HUMAN,tr|M0R0C3|M0R0C3_HUMAN,tr|M0R2F8|M0R2F8_HUMAN" 3 1938.9818 1.13 21309 22482 3 1938.982707 647.3346 Mitochondrial import inner membrane translocase subunit TIM50 OS=Homo sapiens OX=9606 GN=TIMM50 PE=1 SV=2 4.31 3718.1 - 3.18E+06 - - - 0.4451 - 3.195 0.516 - 212.5 1 2 0 0.0009 17 0 0 0 7.78E+07 6.91E+07 - - - 7.2272 1 221125_WJC_METTL3_EV_vs_WT_F02.22483.22483.3 1.76E-12 18/64 R.TVLEHYALEDDPLAAFK.Q "sp|Q3ZCQ8|TIM50_HUMAN,tr|M0R0C3|M0R0C3_HUMAN,tr|M0R2F8|M0R2F8_HUMAN" 3 1930.9676 1.13 21310 22483 3 1930.971562 644.6632 Mitochondrial import inner membrane translocase subunit TIM50 OS=Homo sapiens OX=9606 GN=TIMM50 PE=1 SV=2 4.31 3718.2 - 2.48E+06 - - - 2.029 - 3.619 0.583 - 292.5 1 2 0 0.0039 17 0 0 0 7.78E+07 6.91E+07 - - - 8.2881 1 221125_WJC_METTL3_EV_vs_WT_F02.22484.22484.2 2.13E-09 24/36 K.LGGSLADSYLDEGFLLDK[136.11]K[136.11].L "sp|P78371|TCPB_HUMAN,tr|F8VQ14|F8VQ14_HUMAN,tr|F5GWF6|F5GWF6_HUMAN" 3 2056.0699 0.49 21311 22484 2 2056.071242 1029.0422 T-complex protein 1 subunit beta OS=Homo sapiens OX=9606 GN=CCT2 PE=1 SV=4 4.23 3718.3 - 1.80E+06 - - - 0.6342 - 4.678 0.686 - 2548.3 1 2 0 0.0013 19 0 0 0 6.92E+06 1.42E+07 - - - 7.9006 1 221125_WJC_METTL3_EV_vs_WT_F02.22487.22487.2 2.61E-10 18/30 K.SPGLYFLTAGDQGTLR.V "sp|Q12788|TBL3_HUMAN,tr|J3KNP2|J3KNP2_HUMAN,tr|A0A087WYP7|A0A087WYP7_HUMAN" 3 1694.8628 0.68 21314 22487 2 1694.871878 848.4387 Transducin beta-like protein 3 OS=Homo sapiens OX=9606 GN=TBL3 PE=1 SV=2 5.55 3718.6 - 1.13E+06 - - - 5.365 - 3.269 0.675 - 1210.8 1 2 0 0.0091 16 0 0 0 5.88E+06 8.62E+06 - - - 6.9358 1 221125_WJC_METTL3_EV_vs_WT_F02.22488.22488.2 1.21E-05 14/22 K.DNALLSAIEESR[166.11].K "sp|Q8N1F7|NUP93_HUMAN,tr|H3BM93|H3BM93_HUMAN,tr|H3BV11|H3BV11_HUMAN,tr|H3BRI8|H3BRI8_HUMAN,tr|H3BNN5|H3BNN5_HUMAN,tr|H3BVG0|H3BVG0_HUMAN" 6 1326.6655 1.55 21315 22488 2 1326.662916 664.34 Nuclear pore complex protein Nup93 OS=Homo sapiens OX=9606 GN=NUP93 PE=1 SV=2 4.14 3718.7 - 727821 - - - -1.9319 - 2.897 0.551 - 864.7 1 2 0 -0.0026 12 0 0 0 3.87E+07 2.49E+07 - - - 5.9086 1 221125_WJC_METTL3_EV_vs_WT_F02.22489.22489.2 2.02E-16 23/36 K.LGGSLADSYLDEGFLLDKK.L "sp|P78371|TCPB_HUMAN,tr|F8VQ14|F8VQ14_HUMAN,tr|F5GWF6|F5GWF6_HUMAN" 3 2040.0415 0.49 21316 22489 2 2040.044144 1021.028 T-complex protein 1 subunit beta OS=Homo sapiens OX=9606 GN=CCT2 PE=1 SV=4 4.23 3718.9 - 714257 - - - 1.2774 - 4.474 0.732 - 2166.6 1 2 0 0.0026 19 0 0 0 6.92E+06 1.42E+07 - - - 8.1303 1 221125_WJC_METTL3_EV_vs_WT_F02.22490.22490.2 5.27E-10 17/30 K.SGYAFVDYPDQNWAIR[166.11].A "sp|Q9Y6M1|IF2B2_HUMAN,tr|F8W930|F8W930_HUMAN" 2 1910.8827 1.78 21317 22490 2 1910.879731 956.4486 Insulin-like growth factor 2 mRNA-binding protein 2 OS=Homo sapiens OX=9606 GN=IGF2BP2 PE=1 SV=2 4.21 3719 - 551169 - - - -1.5448 - 3.078 0.741 - 986.2 1 2 0 -0.003 16 0 0 0 1.55E+07 8.69E+06 - - - 7.2772 0.9999 221125_WJC_METTL3_EV_vs_WT_F02.22491.22491.3 0.00057 14/44 K.EVDNLYNIEILR.L sp|Q53HL2|BOREA_HUMAN 1 1489.7777 0.18 21318 22491 3 1489.777897 497.5998 Borealin OS=Homo sapiens OX=9606 GN=CDCA8 PE=1 SV=2 4.14 3719.1 - 546237 - - - 0.1598 - 2.227 0.454 - 235.7 1 2 0 0.0002 12 0 0 0 4.23E+06 2.39E+07 - - - 5.8209 0.9999 221125_WJC_METTL3_EV_vs_WT_F02.22492.22492.3 1.54E-05 13/60 R.ALIAGGGAPEIELALR.L sp|P50991|TCPD_HUMAN 1 1549.8828 0.29 21319 22492 3 1549.886172 517.6349 T-complex protein 1 subunit delta OS=Homo sapiens OX=9606 GN=CCT4 PE=1 SV=4 4.53 3719.2 - 437585 - - - 2.1808 - 2.624 0.437 - 203.2 1 2 0 0.0034 16 0 0 0 2.10E+06 7.23E+06 - - - 5.8865 1 221125_WJC_METTL3_EV_vs_WT_F02.22493.22493.3 9.15E-06 13/44 K.EVDNLYNIEILR[166.11].L sp|Q53HL2|BOREA_HUMAN 1 1499.7859 0.15 21320 22493 3 1499.787697 500.9359 Borealin OS=Homo sapiens OX=9606 GN=CDCA8 PE=1 SV=2 4.14 3719.4 - 432354 - - - 1.1788 - 2.368 0.501 - 253.5 1 2 0 0.0018 12 0 0 0 4.44E+06 2.96E+07 - - - 6.5146 0.9999 221125_WJC_METTL3_EV_vs_WT_F02.22496.22496.2 1.22E-08 14/30 R.TGAIVDVPVGEELLGR[166.11].V "sp|P25705|ATPA_HUMAN,tr|K7EQH4|K7EQH4_HUMAN,tr|K7ERX7|K7ERX7_HUMAN,tr|K7EK77|K7EK77_HUMAN,tr|K7EJP1|K7EJP1_HUMAN" 5 1633.8915 1.45 21321 22496 2 1633.891594 817.953 "ATP synthase subunit alpha, mitochondrial OS=Homo sapiens OX=9606 GN=ATP5F1A PE=1 SV=1" 4.14 3719.8 - 4.60E+06 - - - 0.0845 - 2.638 0.524 - 486.1 1 2 0 0.0001 16 0 0 0 4.16E+08 2.87E+08 - - - 5.2961 0.9998 221125_WJC_METTL3_EV_vs_WT_F02.22497.22497.2 0.0057 20-Dec R.AFITNIPFDVK.W "sp|P52272|HNRPM_HUMAN,tr|M0R019|M0R019_HUMAN,tr|M0R0Y6|M0R0Y6_HUMAN,tr|M0R0N3|M0R0N3_HUMAN,tr|A0A087X0X3|A0A087X0X3_HUMAN,tr|M0QYQ7|M0QYQ7_HUMAN,tr|M0R2T0|M0R2T0_HUMAN" 7 1263.6863 1.71 21322 22497 2 1263.687184 632.8504 Heterogeneous nuclear ribonucleoprotein M OS=Homo sapiens OX=9606 GN=HNRNPM PE=1 SV=3 5.88 3719.8 - 2.40E+06 - - - 0.6805 - 2.12 0.458 - 529.9 1 2 0 0.0009 11 0 0 0 3.59E+08 2.09E+08 - - - 4.4563 1 221125_WJC_METTL3_EV_vs_WT_F02.22498.22498.2 5.02E-13 18/28 R.GFGFVTFENEDVVEK[136.11].V "sp|Q96DH6|MSI2H_HUMAN,tr|B4DHE8|B4DHE8_HUMAN,tr|A0A6Q8PGD8|A0A6Q8PGD8_HUMAN,tr|A0A6Q8PF05|A0A6Q8PF05_HUMAN,tr|B4DM51|B4DM51_HUMAN" 5 1723.8185 1.01 21323 22498 2 1723.819031 862.9165 RNA-binding protein Musashi homolog 2 OS=Homo sapiens OX=9606 GN=MSI2 PE=1 SV=1 4 3719.9 - 1.85E+06 - - - 0.3272 - 3.37 0.732 - 1109.9 1 2 0 0.0006 15 0 0 0 2.32E+08 2.30E+08 - - - 7.4343 1 221125_WJC_METTL3_EV_vs_WT_F02.22499.22499.2 4.72E-11 16/28 R.GFGFVTFENEDVVEK.V "sp|Q96DH6|MSI2H_HUMAN,tr|B4DHE8|B4DHE8_HUMAN,tr|A0A6Q8PGD8|A0A6Q8PGD8_HUMAN,tr|A0A6Q8PF05|A0A6Q8PF05_HUMAN,tr|B4DM51|B4DM51_HUMAN" 5 1715.8043 1.01 21324 22499 2 1715.80143 858.9094 RNA-binding protein Musashi homolog 2 OS=Homo sapiens OX=9606 GN=MSI2 PE=1 SV=1 4 3720.1 - 1.82E+06 - - - -1.6535 - 3.145 0.596 - 837.5 1 2 0 -0.0028 15 0 0 0 2.32E+08 2.30E+08 - - - 6.2592 0.9999 221125_WJC_METTL3_EV_vs_WT_F02.22500.22500.3 3.58E-06 15/52 R.DFNHINVELSLLGK[136.11].K "sp|P32969|RL9_HUMAN,tr|D6RAN4|D6RAN4_HUMAN,tr|A0A2R8Y5Y7|A0A2R8Y5Y7_HUMAN" 3 1605.8606 1.07 21325 22500 3 1605.86488 536.2941 60S ribosomal protein L9 OS=Homo sapiens OX=9606 GN=RPL9 PE=1 SV=1 5.32 3720.2 - 1.58E+06 - - - 2.6609 - 2.932 0.514 - 389.1 1 2 0 0.0043 14 0 0 0 6.48E+07 6.06E+07 - - - 7.1281 1 221125_WJC_METTL3_EV_vs_WT_F02.22501.22501.2 1.94E-08 19/30 K.SPGLYFLTAGDQGTLR[166.11].V "sp|Q12788|TBL3_HUMAN,tr|J3KNP2|J3KNP2_HUMAN,tr|A0A087WYP7|A0A087WYP7_HUMAN" 3 1704.8711 0.68 21326 22501 2 1704.875454 853.4428 Transducin beta-like protein 3 OS=Homo sapiens OX=9606 GN=TBL3 PE=1 SV=2 5.55 3720.3 - 1.55E+06 - - - 2.5803 - 3.089 0.608 - 1376.1 1 2 0 0.0044 16 0 0 0 5.88E+06 8.62E+06 - - - 6.3032 1 221125_WJC_METTL3_EV_vs_WT_F02.22502.22502.2 6.13E-11 16/36 K.IISAASEGGANVFTVSYFK[136.11].N sp|P14868|SYDC_HUMAN 1 1968.0084 1.34 21327 22502 2 1968.0081 985.0115 "Aspartate--tRNA ligase, cytoplasmic OS=Homo sapiens OX=9606 GN=DARS1 PE=1 SV=2" 6 3720.4 - 1.29E+06 - - - -0.1489 - 3.232 0.597 - 724.3 1 2 0 -0.0003 19 0 0 0 1.08E+07 8.05E+06 - - - 6.3345 1 221125_WJC_METTL3_EV_vs_WT_F02.22504.22504.2 1.79E-10 13/32 R.FSGLPSNDEPILSFSPK[136.11].T sp|O00443|P3C2A_HUMAN 1 1841.9291 1.77 21329 22504 2 1841.929245 921.9718 Phosphatidylinositol 4-phosphate 3-kinase C2 domain-containing subunit alpha OS=Homo sapiens OX=9606 GN=PIK3C2A PE=1 SV=2 4.37 3720.7 - 1.11E+06 - - - 0.0896 - 2.438 0.632 - 382.8 1 2 0 0.0002 17 0 0 0 2.45E+07 1.38E+07 - - - 5.8999 1 221125_WJC_METTL3_EV_vs_WT_F02.22505.22505.2 5.01E-10 17/32 K.TLLYNPFPPTNESDVIR.R "sp|Q969X6|UTP4_HUMAN,tr|H3BSH7|H3BSH7_HUMAN,tr|A0A0J9YXV4|A0A0J9YXV4_HUMAN,tr|A0A0J9YWM9|A0A0J9YWM9_HUMAN" 4 1975.0051 1.13 21330 22505 2 1975.008014 988.5098 U3 small nucleolar RNA-associated protein 4 homolog OS=Homo sapiens OX=9606 GN=UTP4 PE=1 SV=1 4.37 3720.8 - 1.09E+06 - - - 1.4795 - 2.881 0.648 - 666.1 1 2 0 0.0029 17 0 0 0 1.01E+07 8.95E+06 - - - 6.4277 1 221125_WJC_METTL3_EV_vs_WT_F02.22506.22506.2 5.66E-12 19/34 K.WNPTAGVAFEYDPDNALR.H sp|P19387|RPB3_HUMAN 1 2034.9436 1.02 21331 22506 2 2034.94365 1018.4791 DNA-directed RNA polymerase II subunit RPB3 OS=Homo sapiens OX=9606 GN=POLR2C PE=1 SV=2 4.03 3720.9 - 977058 - - - 0.0467 - 3.313 0.687 - 676.4 1 2 0 0.0001 18 0 0 0 7.95E+06 7.78E+06 - - - 7.0601 0.9995 221125_WJC_METTL3_EV_vs_WT_F02.22507.22507.2 7.27E-07 17/30 R.GANVIAGVWLEEAGQK.L "sp|Q15149|PLEC_HUMAN,tr|H0YDN1|H0YDN1_HUMAN" 2 1640.8522 1.48 21332 22507 2 1640.847031 821.4334 Plectin OS=Homo sapiens OX=9606 GN=PLEC PE=1 SV=3 4.53 3721.1 - 942570 - - - -3.163 - 2.684 0.494 - 787.8 1 2 0 -0.0052 16 0 0 0 4.71E+06 3.19E+06 - - - 5.1154 0.9481 221125_WJC_METTL3_EV_vs_WT_F02.22508.22508.3 0.0028 Nov-48 R.C[160.03]SEGSFLLTTFPR[166.11].P "sp|Q15233|NONO_HUMAN,tr|A0A7I2V535|A0A7I2V535_HUMAN,tr|A0A7I2V4N2|A0A7I2V4N2_HUMAN,tr|A0A7I2V464|A0A7I2V464_HUMAN,tr|A0A7P0MRW0|A0A7P0MRW0_HUMAN,tr|H7C367|H7C367_HUMAN,tr|A0A7I2V4J2|A0A7I2V4J2_HUMAN,tr|A0A7I2V5Y7|A0A7I2V5Y7_HUMAN" 8 1523.7318 1.6 21333 22508 3 1523.733673 508.9179 Non-POU domain-containing octamer-binding protein OS=Homo sapiens OX=9606 GN=NONO PE=1 SV=4 5.99 3721.2 - 855911 - - - 1.2391 - 1.849 0.337 - 128 1 1 0 0.0019 13 0 0 0 5.99E+06 3.75E+06 - - - 3.9632 1 221125_WJC_METTL3_EV_vs_WT_F02.22509.22509.2 2.22E-08 14/30 R.GANVIAGVWLEEAGQK[136.11].L "sp|Q15149|PLEC_HUMAN,tr|H0YDN1|H0YDN1_HUMAN" 2 1648.8664 1.48 21334 22509 2 1648.874247 825.4405 Plectin OS=Homo sapiens OX=9606 GN=PLEC PE=1 SV=3 4.53 3721.3 - 784900 - - - 4.7463 - 3.014 0.568 - 645.1 1 2 0 0.0078 16 0 0 0 4.71E+06 3.19E+06 - - - 5.9462 0.9911 221125_WJC_METTL3_EV_vs_WT_F02.22510.22510.3 0.0821 Dec-60 K.SPGLYFLTAGDQGTLR[166.11].V "sp|Q12788|TBL3_HUMAN,tr|J3KNP2|J3KNP2_HUMAN,tr|A0A087WYP7|A0A087WYP7_HUMAN" 3 1704.8711 1 21335 22510 3 1704.873088 569.2976 Transducin beta-like protein 3 OS=Homo sapiens OX=9606 GN=TBL3 PE=1 SV=2 5.55 3721.4 - 758699 - - - 1.1925 - 1.812 0.173 - 111 1 2 0 0.002 16 0 0 0 3.14E+06 3.14E+06 - - - 1.9934 1 221125_WJC_METTL3_EV_vs_WT_F02.22511.22511.2 1.91E-09 15/34 K.WNPTAGVAFEYDPDNALR[166.11].H sp|P19387|RPB3_HUMAN 1 2044.9518 1.02 21336 22511 2 2044.953961 1023.4832 DNA-directed RNA polymerase II subunit RPB3 OS=Homo sapiens OX=9606 GN=POLR2C PE=1 SV=2 4.03 3721.6 - 691324 - - - 1.0445 - 3.041 0.68 - 467.3 1 2 0 0.0021 18 0 0 0 7.95E+06 7.78E+06 - - - 6.7972 0.9999 221125_WJC_METTL3_EV_vs_WT_F02.22513.22513.3 0.000373 Sep-44 K.DNALLSAIEESR.K "sp|Q8N1F7|NUP93_HUMAN,tr|H3BM93|H3BM93_HUMAN,tr|H3BV11|H3BV11_HUMAN,tr|H3BRI8|H3BRI8_HUMAN,tr|H3BNN5|H3BNN5_HUMAN,tr|H3BVG0|H3BVG0_HUMAN" 6 1316.6572 1.02 21338 22513 3 1316.656321 439.893 Nuclear pore complex protein Nup93 OS=Homo sapiens OX=9606 GN=NUP93 PE=1 SV=2 4.14 3721.8 - 329047 - - - -0.6744 - 1.951 0.445 - 153.9 1 2 0 -0.0009 12 0 0 0 2.35E+06 2.30E+06 - - - 5.3536 1 221125_WJC_METTL3_EV_vs_WT_F02.22516.22516.2 1.39E-08 24-Dec K.ELAPYDENWFYTR.A "sp|P39019|RS19_HUMAN,tr|M0R140|M0R140_HUMAN,tr|M0R2L9|M0R2L9_HUMAN,tr|M0QYF7|M0QYF7_HUMAN" 4 1702.7627 1.14 21339 22516 2 1702.762285 852.3886 40S ribosomal protein S19 OS=Homo sapiens OX=9606 GN=RPS19 PE=1 SV=2 4.14 3722.2 - 1.28E+07 - - - -0.2655 - 2.496 0.661 - 626.1 1 2 0 -0.0005 13 0 0 0 1.05E+09 9.19E+08 - - - 6.2706 0.9984 221125_WJC_METTL3_EV_vs_WT_F02.22517.22517.3 4.60E-09 19/76 K.HAASDVDLEIESLLNQQSTK[136.11].E "sp|Q86U44|MTA70_HUMAN,tr|F5H6D8|F5H6D8_HUMAN,tr|H0YFV6|H0YFV6_HUMAN,tr|B4DTN4|B4DTN4_HUMAN" 4 2205.1005 0.17 21340 22517 3 2206.097816 736.0408 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 4.31 3722.3 - 9.58E+06 - - - 452.2969 - 3.634 0.519 - 412.1 1 2 0 0.9974 20 0 0 0 1.55E+07 9.19E+07 - - - 7.1805 0.9998 221125_WJC_METTL3_EV_vs_WT_F02.22518.22518.2 0.00098 13/20 R.AFITNIPFDVK[136.11].W "sp|P52272|HNRPM_HUMAN,tr|M0R019|M0R019_HUMAN,tr|M0R0Y6|M0R0Y6_HUMAN,tr|M0R0N3|M0R0N3_HUMAN,tr|A0A087X0X3|A0A087X0X3_HUMAN,tr|M0QYQ7|M0QYQ7_HUMAN,tr|M0R2T0|M0R2T0_HUMAN" 7 1271.7005 1.71 21341 22518 2 1271.702512 636.8575 Heterogeneous nuclear ribonucleoprotein M OS=Homo sapiens OX=9606 GN=HNRNPM PE=1 SV=3 5.88 3722.3 - 6.81E+06 - - - 1.5633 - 2.293 0.462 - 628.3 1 2 0 0.002 11 0 0 0 3.59E+08 2.09E+08 - - - 4.6977 1 221125_WJC_METTL3_EV_vs_WT_F02.22520.22520.3 4.26E-13 20/72 R.PVIVEPLEQLDDEDGLPEK.L sp|P23246|SFPQ_HUMAN 1 2134.0681 1.04 21343 22520 3 2134.07133 712.3633 "Splicing factor, proline- and glutamine-rich OS=Homo sapiens OX=9606 GN=SFPQ PE=1 SV=2" 3.66 3722.4 - 6.29E+06 - - - 1.492 - 3.84 0.669 - 440.6 1 1 0 0.0032 19 0 0 0 1.11E+08 1.07E+08 - - - 9.3034 0.9997 221125_WJC_METTL3_EV_vs_WT_F02.22522.22522.2 0.000101 18-Nov K.LTLSALIDGK.N "sp|Q9Y277|VDAC3_HUMAN,sp|P21796|VDAC1_HUMAN" 2 1029.607 1.28 21345 22522 2 1029.608311 515.8108 Voltage-dependent anion-selective channel protein 3 OS=Homo sapiens OX=9606 GN=VDAC3 PE=1 SV=1 5.84 3722.6 - 1.88E+06 - - - 1.2626 - 2.373 0.376 - 299.5 1 2 0 0.0013 10 0 0 0 1.01E+08 7.90E+07 - - - 4.2298 1 221125_WJC_METTL3_EV_vs_WT_F02.22523.22523.3 7.27E-05 15/48 R.LDIISEDISELQK[136.11].N sp|Q7Z3B4|NUP54_HUMAN 1 1509.8018 2.24 21346 22523 3 1509.802315 504.2745 Nucleoporin p54 OS=Homo sapiens OX=9606 GN=NUP54 PE=1 SV=2 3.92 3722.7 - 1.83E+06 - - - 0.3709 - 2.658 0.467 - 368 1 2 0 0.0006 13 0 0 0 3.97E+07 1.77E+07 - - - 6.3969 1 221125_WJC_METTL3_EV_vs_WT_F02.22524.22524.3 1.13E-06 13/48 K.ELAPYDENWFYTR[166.11].A "sp|P39019|RS19_HUMAN,tr|M0R140|M0R140_HUMAN,tr|M0R2L9|M0R2L9_HUMAN,tr|M0QYF7|M0QYF7_HUMAN" 4 1712.771 1.18 21347 22524 3 1712.771724 571.9309 40S ribosomal protein S19 OS=Homo sapiens OX=9606 GN=RPS19 PE=1 SV=2 4.14 3722.7 - 1.82E+06 - - - 0.4186 - 2.436 0.563 - 259.9 1 2 0 0.0007 13 0 0 0 1.06E+08 8.94E+07 - - - 7.2307 1 221125_WJC_METTL3_EV_vs_WT_F02.22525.22525.3 5.27E-05 Nov-48 K.ELAPYDENWFYTR.A "sp|P39019|RS19_HUMAN,tr|M0R140|M0R140_HUMAN,tr|M0R2L9|M0R2L9_HUMAN,tr|M0QYF7|M0QYF7_HUMAN" 4 1702.7627 1.18 21348 22525 3 1702.764816 568.5949 40S ribosomal protein S19 OS=Homo sapiens OX=9606 GN=RPS19 PE=1 SV=2 4.14 3722.8 - 1.75E+06 - - - 1.221 - 2.205 0.582 - 175.5 1 2 0 0.0021 13 0 0 0 1.06E+08 8.94E+07 - - - 7.172 1 221125_WJC_METTL3_EV_vs_WT_F02.22526.22526.2 2.00E-13 20/36 R.PVIVEPLEQLDDEDGLPEK[136.11].L sp|P23246|SFPQ_HUMAN 1 2142.0823 1.08 21349 22526 2 2142.082883 1072.0484 "Splicing factor, proline- and glutamine-rich OS=Homo sapiens OX=9606 GN=SFPQ PE=1 SV=2" 3.66 3722.9 - 1.52E+06 - - - 0.2507 - 3.894 0.759 - 862.7 1 1 0 0.0005 19 0 0 0 3.26E+07 3.02E+07 - - - 7.989 0.9908 221125_WJC_METTL3_EV_vs_WT_F02.22530.22530.3 0.141 Dec-60 K.YVIWSADMSHVALLAK[136.11].H "sp|P53621|COPA_HUMAN,tr|A0A3B3ISC6|A0A3B3ISC6_HUMAN,tr|A0A3B3ITV3|A0A3B3ITV3_HUMAN,tr|A0A3B3IS84|A0A3B3IS84_HUMAN,tr|A0A3B3IU89|A0A3B3IU89_HUMAN,tr|A0A3B3IT15|A0A3B3IT15_HUMAN" 6 1810.9531 0.37 21353 22530 3 1810.949094 604.6583 Coatomer subunit alpha OS=Homo sapiens OX=9606 GN=COPA PE=1 SV=2 6.74 3723.4 - 719720 - - - -2.227 - 1.568 0.236 - 84.8 1 2 0 -0.004 16 0 0 0 1.32E+06 3.62E+06 - - - 2.3242 1 221125_WJC_METTL3_EV_vs_WT_F02.22531.22531.2 1.53E-08 19/32 R.IEFGVDEVIEPSDTLPR.T "sp|Q14694|UBP10_HUMAN,tr|H3BQC6|H3BQC6_HUMAN" 2 1914.9575 0.93 21354 22531 2 1914.967287 958.486 Ubiquitin carboxyl-terminal hydrolase 10 OS=Homo sapiens OX=9606 GN=USP10 PE=1 SV=2 3.83 3723.5 - 643840 - - - 5.1244 - 3.286 0.635 - 923 1 2 0 0.0098 17 0 0 0 4.84E+06 5.22E+06 - - - 6.6529 0.9938 221125_WJC_METTL3_EV_vs_WT_F02.22533.22533.3 0.0444 Aug-40 R.ENYVWNVLLHR[166.11].G "sp|Q92538|GBF1_HUMAN,tr|A0A7I2V3S0|A0A7I2V3S0_HUMAN,tr|A0A7I2V3H2|A0A7I2V3H2_HUMAN,tr|A0A7I2V2L4|A0A7I2V2L4_HUMAN,tr|A0A7I2YQM2|A0A7I2YQM2_HUMAN,tr|A0A7I2V3Y5|A0A7I2V3Y5_HUMAN,tr|A0A669KBG8|A0A669KBG8_HUMAN,tr|A0A7I2V2L5|A0A7I2V2L5_HUMAN,tr|A0A7I2V514|A0A7I2V514_HUMAN,tr|A0A7I2YQ65|A0A7I2YQ65_HUMAN,tr|A0A669KB10|A0A669KB10_HUMAN,tr|A0A7I2V452|A0A7I2V452_HUMAN,tr|A0A7I2V4K2|A0A7I2V4K2_HUMAN,tr|A0A7I2V529|A0A7I2V529_HUMAN,tr|A0A7P0RGV0|A0A7P0RGV0_HUMAN" 15 1451.7549 0.66 21356 22533 3 1451.755439 484.9256 Golgi-specific brefeldin A-resistance guanine nucleotide exchange factor 1 OS=Homo sapiens OX=9606 GN=GBF1 PE=1 SV=2 6.85 3723.8 - 423970 - - - 0.3692 - 1.752 0.176 - 95 1 2 0 0.0005 11 0 0 0 1.81E+06 2.75E+06 - - - 2.0951 1 221125_WJC_METTL3_EV_vs_WT_F02.22538.22538.2 2.32E-07 13/24 K.ELAPYDENWFYTR[166.11].A "sp|P39019|RS19_HUMAN,tr|M0R140|M0R140_HUMAN,tr|M0R2L9|M0R2L9_HUMAN,tr|M0QYF7|M0QYF7_HUMAN" 4 1712.771 1.14 21359 22538 2 1712.770372 857.3928 40S ribosomal protein S19 OS=Homo sapiens OX=9606 GN=RPS19 PE=1 SV=2 4.14 3724.4 - 5.74E+07 - - - -0.3707 - 2.574 0.647 - 761.5 1 2 0 -0.0006 13 0 0 0 1.05E+09 9.17E+08 - - - 6.2461 0.9998 221125_WJC_METTL3_EV_vs_WT_F02.22539.22539.2 0.000356 24-Dec R.LDIISEDISELQK.N sp|Q7Z3B4|NUP54_HUMAN 1 1501.7876 2.13 21360 22539 2 1501.787209 751.9011 Nucleoporin p54 OS=Homo sapiens OX=9606 GN=NUP54 PE=1 SV=2 3.92 3724.5 - 2.36E+07 - - - -0.2304 - 2.648 0.398 - 510 1 2 0 -0.0003 13 0 0 0 2.17E+08 1.02E+08 - - - 4.4798 0.9999 221125_WJC_METTL3_EV_vs_WT_F02.22542.22542.2 1.52E-05 24-Dec R.LDIISEDISELQK[136.11].N sp|Q7Z3B4|NUP54_HUMAN 1 1509.8018 2.12 21363 22542 2 1509.801806 755.9082 Nucleoporin p54 OS=Homo sapiens OX=9606 GN=NUP54 PE=1 SV=2 3.92 3724.6 - 1.07E+07 - - - 0.0338 - 2.378 0.522 - 575.1 1 2 0 0.0001 13 0 0 0 2.16E+08 1.02E+08 - - - 5.1198 0.9998 221125_WJC_METTL3_EV_vs_WT_F02.22543.22543.2 0.00102 18-Oct K.LTLSALIDGK[136.11].N "sp|Q9Y277|VDAC3_HUMAN,sp|P21796|VDAC1_HUMAN" 2 1037.6212 1.28 21364 22543 2 1037.621935 519.8179 Voltage-dependent anion-selective channel protein 3 OS=Homo sapiens OX=9606 GN=VDAC3 PE=1 SV=1 5.84 3724.7 - 6.91E+06 - - - 0.6977 - 2.168 0.434 - 280 1 2 0 0.0007 10 0 0 0 1.01E+08 7.90E+07 - - - 4.4062 1 221125_WJC_METTL3_EV_vs_WT_F02.22546.22546.3 1.26E-08 24/68 K.LIHFSGVALGEAC[160.03]TIVLR[166.11].G "sp|P78371|TCPB_HUMAN,tr|F8VQ14|F8VQ14_HUMAN,tr|F5GWF6|F5GWF6_HUMAN" 3 1965.0745 0.36 21367 22546 3 1965.073058 656.0321 T-complex protein 1 subunit beta OS=Homo sapiens OX=9606 GN=CCT2 PE=1 SV=4 6.74 3724.8 - 5.36E+06 - - - -0.7455 - 3.809 0.617 - 851.9 1 2 0 -0.0015 18 0 0 0 2.13E+07 5.85E+07 - - - 8.7487 0.9999 221125_WJC_METTL3_EV_vs_WT_F02.22547.22547.2 8.22E-05 13/22 K.DNALLSAIEESR.K "sp|Q8N1F7|NUP93_HUMAN,tr|H3BM93|H3BM93_HUMAN,tr|H3BV11|H3BV11_HUMAN,tr|H3BRI8|H3BRI8_HUMAN,tr|H3BNN5|H3BNN5_HUMAN,tr|H3BVG0|H3BVG0_HUMAN" 6 1316.6572 0.82 21368 22547 2 1316.657498 659.3359 Nuclear pore complex protein Nup93 OS=Homo sapiens OX=9606 GN=NUP93 PE=1 SV=2 4.14 3724.9 - 4.18E+06 - - - 0.2195 - 2.781 0.521 - 666 1 2 0 0.0003 12 0 0 0 4.03E+07 4.94E+07 - - - 5.5802 0.9991 221125_WJC_METTL3_EV_vs_WT_F02.22549.22549.3 1.75E-08 15/60 R.TGAIVDVPVGEELLGR.V "sp|P25705|ATPA_HUMAN,tr|K7EQH4|K7EQH4_HUMAN,tr|K7ERX7|K7ERX7_HUMAN,tr|K7EK77|K7EK77_HUMAN,tr|K7EJP1|K7EJP1_HUMAN" 5 1623.8832 0.98 21370 22549 3 1623.888121 542.3017 "ATP synthase subunit alpha, mitochondrial OS=Homo sapiens OX=9606 GN=ATP5F1A PE=1 SV=1" 4.14 3725 - 2.77E+06 - - - 3.039 - 3.217 0.26 - 298.4 1 2 0 0.0049 16 0 0 0 3.25E+07 3.33E+07 - - - 4.4355 0.9527 221125_WJC_METTL3_EV_vs_WT_F02.22550.22550.2 0.00345 18-Aug R.KQPELLMMLN.C "sp|P52732|KIF11_HUMAN,tr|A0A7I2V3A9|A0A7I2V3A9_HUMAN" 2 1215.6356 22.39 21371 22550 2 1215.636348 608.8251 Kinesin-like protein KIF11 OS=Homo sapiens OX=9606 GN=KIF11 PE=1 SV=2 6 3725.1 - 1.98E+06 - - - 0.6556 - 1.641 0.304 - 154.1 1 1 0 0.0008 10 0 0 0 1.50E+07 6.72E+05 - - - 2.6686 1 221125_WJC_METTL3_EV_vs_WT_F02.22551.22551.2 1.57E-09 13/26 R.TAYVLADVMDDQLK[136.11].S sp|Q69YN4|VIR_HUMAN 1 1588.7898 0.34 21372 22551 2 1588.789502 795.4022 Protein virilizer homolog OS=Homo sapiens OX=9606 GN=VIRMA PE=1 SV=2 3.93 3725.2 - 1.62E+06 - - - -0.1939 - 2.932 0.636 - 447.4 1 2 0 -0.0003 14 0 0 0 6.80E+06 2.03E+07 - - - 6.4378 1 221125_WJC_METTL3_EV_vs_WT_F02.22552.22552.2 1.07E-08 20/30 K.IPDEFDNDPILVQQLR.R "sp|Q3ZCQ8|TIM50_HUMAN,tr|M0R047|M0R047_HUMAN" 2 1910.9738 1.21 21373 22552 2 1910.975714 956.4942 Mitochondrial import inner membrane translocase subunit TIM50 OS=Homo sapiens OX=9606 GN=TIMM50 PE=1 SV=2 3.84 3725.4 - 1.55E+06 - - - 1.0058 - 3.689 0.658 - 893.5 1 2 0 0.0019 16 0 0 0 2.67E+07 2.20E+07 - - - 7.1097 1 221125_WJC_METTL3_EV_vs_WT_F02.22553.22553.2 8.92E-11 19/36 R.YEGILYTIDTDNSTVALAK[136.11].V "sp|Q9BX40|LS14B_HUMAN,tr|Q5TBQ1|Q5TBQ1_HUMAN,tr|A0A0C4DFV2|A0A0C4DFV2_HUMAN,tr|Q5TBQ0|Q5TBQ0_HUMAN" 4 2094.0612 0.76 21374 22553 2 2094.06358 1048.0379 Protein LSM14 homolog B OS=Homo sapiens OX=9606 GN=LSM14B PE=1 SV=1 4.03 3725.5 - 1.38E+06 - - - 1.1284 - 3.571 0.667 - 948.2 1 2 0 0.0024 19 0 0 0 1.85E+07 2.44E+07 - - - 7.0961 1 221125_WJC_METTL3_EV_vs_WT_F02.22554.22554.2 2.24E-07 18/24 R.SIQLDGLVWGASK[136.11].L "sp|P29692|EF1D_HUMAN,tr|A0A087X1X7|A0A087X1X7_HUMAN,tr|E9PQZ1|E9PQZ1_HUMAN,tr|E9PQC9|E9PQC9_HUMAN,tr|E9PRY8|E9PRY8_HUMAN,tr|E9PK01|E9PK01_HUMAN,tr|H0YE58|H0YE58_HUMAN" 7 1380.7493 1.22 21375 22554 2 1380.74611 691.3819 Elongation factor 1-delta OS=Homo sapiens OX=9606 GN=EEF1D PE=1 SV=5 5.55 3725.6 - 1.11E+06 - - - -2.285 - 3.13 0.586 - 939.8 1 2 0 -0.0032 13 0 0 0 8.82E+07 7.25E+07 - - - 6.2967 0.9999 221125_WJC_METTL3_EV_vs_WT_F02.22555.22555.3 1.02E-05 15/56 R.GFGFVTFENEDVVEK[136.11].V "sp|Q96DH6|MSI2H_HUMAN,tr|B4DHE8|B4DHE8_HUMAN,tr|A0A6Q8PGD8|A0A6Q8PGD8_HUMAN,tr|A0A6Q8PF05|A0A6Q8PF05_HUMAN,tr|B4DM51|B4DM51_HUMAN" 5 1723.8185 0.1 21376 22555 3 1723.816383 575.6134 RNA-binding protein Musashi homolog 2 OS=Homo sapiens OX=9606 GN=MSI2 PE=1 SV=1 4 3725.7 - 925129 - - - -1.2089 - 2.197 0.485 - 174.9 1 2 0 -0.0021 15 0 0 0 7.15E+05 7.41E+06 - - - 6.0005 1 221125_WJC_METTL3_EV_vs_WT_F02.22556.22556.2 2.90E-07 30-Nov K.SGYAFVDYPDQNWAIR.A "sp|Q9Y6M1|IF2B2_HUMAN,tr|F8W930|F8W930_HUMAN" 2 1900.8744 1.78 21377 22556 2 1900.873533 951.4445 Insulin-like growth factor 2 mRNA-binding protein 2 OS=Homo sapiens OX=9606 GN=IGF2BP2 PE=1 SV=2 4.21 3725.8 - 889942 - - - -0.4629 - 2.686 0.59 - 274.2 1 2 0 -0.0009 16 0 0 0 1.55E+07 8.69E+06 - - - 5.8276 0.9055 221125_WJC_METTL3_EV_vs_WT_F02.22559.22559.2 2.45 Aug-36 K.IISAASEGGANVFTVSYFK.N sp|P14868|SYDC_HUMAN 1 1959.9942 1.29 21379 22559 2 1959.98766 981.0044 "Aspartate--tRNA ligase, cytoplasmic OS=Homo sapiens OX=9606 GN=DARS1 PE=1 SV=2" 6 3726.3 - 500071 - - - -3.3332 - 1.364 0.087 - 41.2 3 2 0 -0.0065 19 0 0 0 1.04E+07 8.05E+06 - - - 0.2316 0.9999 221125_WJC_METTL3_EV_vs_WT_F02.22561.22561.2 7.14E-05 24-Dec R.FETFC[160.03]LDPSLVTK[136.11].Q sp|Q9UHB9|SRP68_HUMAN 1 1563.7734 0.9 21380 22561 2 1563.77442 782.894 Signal recognition particle subunit SRP68 OS=Homo sapiens OX=9606 GN=SRP68 PE=1 SV=2 4.37 3726.5 - 2.04E+06 - - - 0.6318 - 2.245 0.497 - 457.8 1 2 0 0.001 13 0 0 0 1.74E+07 1.94E+07 - - - 4.7871 0.8662 221125_WJC_METTL3_EV_vs_WT_F02.22564.22564.3 6.48E-05 14/60 R.TGAIVDVPVGEELLGR[166.11].V "sp|P25705|ATPA_HUMAN,tr|K7EQH4|K7EQH4_HUMAN,tr|K7ERX7|K7ERX7_HUMAN,tr|K7EK77|K7EK77_HUMAN,tr|K7EJP1|K7EJP1_HUMAN" 5 1633.8915 0.97 21383 22564 3 1633.898935 545.6378 "ATP synthase subunit alpha, mitochondrial OS=Homo sapiens OX=9606 GN=ATP5F1A PE=1 SV=1" 4.14 3726.7 - 4.28E+06 - - - 4.5774 - 2.714 0.064 - 329.3 2 2 0 0.0075 16 0 0 0 3.25E+07 3.34E+07 - - - 1.674 1 221125_WJC_METTL3_EV_vs_WT_F02.22565.22565.3 2.70E-09 19/60 K.IPDEFDNDPILVQQLR[166.11].R "sp|Q3ZCQ8|TIM50_HUMAN,tr|M0R047|M0R047_HUMAN" 2 1920.9821 1.1 21384 22565 3 1920.982297 641.3346 Mitochondrial import inner membrane translocase subunit TIM50 OS=Homo sapiens OX=9606 GN=TIMM50 PE=1 SV=2 3.84 3726.7 - 3.14E+06 - - - 0.1223 - 2.944 0.564 - 508.6 1 2 0 0.0002 16 0 0 0 3.86E+07 3.50E+07 - - - 7.5985 1 221125_WJC_METTL3_EV_vs_WT_F02.22567.22567.3 1.82E-08 15/56 R.IAHIPLYFVNAQFPR.F "sp|Q9NRG9|AAAS_HUMAN,tr|F8VZ44|F8VZ44_HUMAN" 2 1784.9726 1.04 21386 22567 3 1784.96991 595.9981 Aladin OS=Homo sapiens OX=9606 GN=AAAS PE=1 SV=1 8.75 3726.8 - 2.37E+06 - - - -1.5126 - 2.778 0.525 - 302.8 1 2 0 -0.0027 15 0 0 0 2.23E+07 2.14E+07 - - - 7.0586 1 221125_WJC_METTL3_EV_vs_WT_F02.22568.22568.2 5.20E-12 19/36 R.YEGILYTIDTDNSTVALAK.V "sp|Q9BX40|LS14B_HUMAN,tr|Q5TBQ1|Q5TBQ1_HUMAN,tr|A0A0C4DFV2|A0A0C4DFV2_HUMAN,tr|Q5TBQ0|Q5TBQ0_HUMAN" 4 2086.047 0.76 21387 22568 2 2086.043788 1044.0308 Protein LSM14 homolog B OS=Homo sapiens OX=9606 GN=LSM14B PE=1 SV=1 4.03 3727 - 1.85E+06 - - - -1.5479 - 3.646 0.672 - 899.4 1 2 0 -0.0032 19 0 0 0 1.85E+07 2.44E+07 - - - 7.1838 1 221125_WJC_METTL3_EV_vs_WT_F02.22569.22569.2 2.87E-13 24/30 K.IPDEFDNDPILVQQLR[166.11].R "sp|Q3ZCQ8|TIM50_HUMAN,tr|M0R047|M0R047_HUMAN" 2 1920.9821 1.21 21388 22569 2 1920.982552 961.4983 Mitochondrial import inner membrane translocase subunit TIM50 OS=Homo sapiens OX=9606 GN=TIMM50 PE=1 SV=2 3.84 3727.1 - 1.73E+06 - - - 0.2551 - 3.93 0.707 - 1604 1 2 0 0.0005 16 0 0 0 2.67E+07 2.20E+07 - - - 7.6276 1 221125_WJC_METTL3_EV_vs_WT_F02.22575.22575.3 2.20E-11 17/72 R.YEGILYTIDTDNSTVALAK[136.11].V "sp|Q9BX40|LS14B_HUMAN,tr|Q5TBQ1|Q5TBQ1_HUMAN,tr|A0A0C4DFV2|A0A0C4DFV2_HUMAN,tr|Q5TBQ0|Q5TBQ0_HUMAN" 4 2094.0612 0.69 21392 22575 3 2094.062539 699.0277 Protein LSM14 homolog B OS=Homo sapiens OX=9606 GN=LSM14B PE=1 SV=1 4.03 3727.8 - 4.68E+06 - - - 0.6313 - 3.485 0.592 - 503.8 1 2 0 0.0013 19 0 0 0 2.24E+07 3.27E+07 - - - 8.2071 1 221125_WJC_METTL3_EV_vs_WT_F02.22579.22579.3 9.93E-09 14/56 R.NENQLIIFADDTYPR[166.11].W sp|Q15393|SF3B3_HUMAN 1 1817.8823 1.35 21396 22579 3 1817.882178 606.9681 Splicing factor 3B subunit 3 OS=Homo sapiens OX=9606 GN=SF3B3 PE=1 SV=4 4.03 3728 - 2.84E+06 - - - -0.0935 - 2.845 0.585 - 352.2 1 2 0 -0.0002 15 0 0 0 2.31E+07 1.70E+07 - - - 7.7904 0.9998 221125_WJC_METTL3_EV_vs_WT_F02.22580.22580.2 0.000258 20-Sep K.ATNDEIFSILK[136.11].D sp|Q09161|NCBP1_HUMAN 1 1257.6696 0.98 21397 22580 2 1257.670924 629.8421 Nuclear cap-binding protein subunit 1 OS=Homo sapiens OX=9606 GN=NCBP1 PE=1 SV=1 4.37 3728.1 - 2.62E+06 - - - 1.0384 - 2.196 0.438 - 343.7 1 2 0 0.0013 11 0 0 0 2.26E+07 2.31E+07 - - - 4.4037 1 221125_WJC_METTL3_EV_vs_WT_F02.22581.22581.2 1.89E-11 19/28 R.NENQLIIFADDTYPR.W sp|Q15393|SF3B3_HUMAN 1 1807.8741 1.13 21398 22581 2 1807.871916 904.9443 Splicing factor 3B subunit 3 OS=Homo sapiens OX=9606 GN=SF3B3 PE=1 SV=4 4.03 3728.2 - 2.16E+06 - - - -1.1959 - 3.692 0.729 - 1465.4 1 2 0 -0.0022 15 0 0 0 2.05E+07 1.81E+07 - - - 7.636 1 221125_WJC_METTL3_EV_vs_WT_F02.22582.22582.2 1.03E-09 17/28 R.NENQLIIFADDTYPR[166.11].W sp|Q15393|SF3B3_HUMAN 1 1817.8823 1.13 21399 22582 2 1817.881947 909.9485 Splicing factor 3B subunit 3 OS=Homo sapiens OX=9606 GN=SF3B3 PE=1 SV=4 4.03 3728.4 - 1.92E+06 - - - -0.2206 - 3.506 0.643 - 1199.5 1 2 0 -0.0004 15 0 0 0 2.05E+07 1.81E+07 - - - 6.8743 0.9999 221125_WJC_METTL3_EV_vs_WT_F02.22586.22586.3 5.93E-06 Dec-48 R.SIQLDGLVWGASK.L "sp|P29692|EF1D_HUMAN,tr|A0A087X1X7|A0A087X1X7_HUMAN,tr|E9PQZ1|E9PQZ1_HUMAN,tr|E9PQC9|E9PQC9_HUMAN,tr|E9PRY8|E9PRY8_HUMAN,tr|E9PK01|E9PK01_HUMAN,tr|H0YE58|H0YE58_HUMAN" 7 1372.7351 1.36 21403 22586 3 1372.73452 458.5856 Elongation factor 1-delta OS=Homo sapiens OX=9606 GN=EEF1D PE=1 SV=5 5.55 3728.8 - 706785 - - - -0.397 - 2.266 0.431 - 242.8 1 2 0 -0.0005 13 0 0 0 5.28E+06 3.89E+06 - - - 5.563 0.9998 221125_WJC_METTL3_EV_vs_WT_F02.22589.22589.2 4.50E-06 14/30 K.VTLVVGASQDIIPQLK[136.11].K "sp|P21964|COMT_HUMAN,tr|E7EUU8|E7EUU8_HUMAN,tr|E7EMS6|E7EMS6_HUMAN,tr|H7BZ45|H7BZ45_HUMAN,tr|A0A7I2V3G7|A0A7I2V3G7_HUMAN,tr|A0A7I2V370|A0A7I2V370_HUMAN" 6 1687.9964 0.97 21406 22589 2 1687.997897 845.0055 Catechol O-methyltransferase OS=Homo sapiens OX=9606 GN=COMT PE=1 SV=2 5.81 3729.2 - 546335 - - - 0.9034 - 2.293 0.495 - 405 1 2 0 0.0015 16 0 0 0 5.83E+06 6.01E+06 - - - 4.7368 0.9999 221125_WJC_METTL3_EV_vs_WT_F02.22594.22594.2 2.25E-07 14/32 R.GLPLVDDGGWNTVPISK.G "sp|Q04637|IF4G1_HUMAN,tr|H7C044|H7C044_HUMAN,tr|E7EUU4|E7EUU4_HUMAN,tr|E9PGM1|E9PGM1_HUMAN,tr|E7EX73|E7EX73_HUMAN,tr|A0A7I2Y1C3|A0A7I2Y1C3_HUMAN" 6 1766.9203 0.95 21410 22594 2 1766.921764 884.4674 Eukaryotic translation initiation factor 4 gamma 1 OS=Homo sapiens OX=9606 GN=EIF4G1 PE=1 SV=4 4.21 3729.8 - 1.22E+06 - - - 0.8286 - 2.654 0.567 - 321.4 1 2 0 0.0015 17 0 0 0 2.61E+07 2.74E+07 - - - 5.6281 0.9996 221125_WJC_METTL3_EV_vs_WT_F02.22596.22596.2 5.48E-06 20-Oct K.ATNDEIFSILK.D sp|Q09161|NCBP1_HUMAN 1 1249.6554 0.98 21412 22596 2 1249.658902 625.835 Nuclear cap-binding protein subunit 1 OS=Homo sapiens OX=9606 GN=NCBP1 PE=1 SV=1 4.37 3729.9 - 3.70E+06 - - - 2.788 - 2.325 0.538 - 463.5 1 2 0 0.0035 11 0 0 0 2.26E+07 2.31E+07 - - - 5.296 1 221125_WJC_METTL3_EV_vs_WT_F02.22600.22600.3 1.32E-06 24/88 K.FLAAGTHLGGTNLDFQMEQYIYK[136.11].R "sp|P08865|RSSA_HUMAN,tr|C9J9K3|C9J9K3_HUMAN,tr|A0A0C4DG17|A0A0C4DG17_HUMAN,tr|F8WD59|F8WD59_HUMAN" 4 2624.2825 0.68 21416 22600 3 2624.28323 875.7681 40S ribosomal protein SA OS=Homo sapiens OX=9606 GN=RPSA PE=1 SV=4 5.32 3730.3 - 1.62E+06 - - - 0.2934 - 4.169 0.549 - 493.9 1 2 0 0.0008 23 0 0 0 1.38E+07 2.03E+07 - - - 8.0098 1 221125_WJC_METTL3_EV_vs_WT_F02.22602.22602.2 2.85E-09 16/32 R.GLPLVDDGGWNTVPISK[136.11].G "sp|Q04637|IF4G1_HUMAN,tr|H7C044|H7C044_HUMAN,tr|E7EUU4|E7EUU4_HUMAN,tr|E9PGM1|E9PGM1_HUMAN,tr|E7EX73|E7EX73_HUMAN,tr|A0A7I2Y1C3|A0A7I2Y1C3_HUMAN" 6 1774.9345 0.94 21418 22602 2 1774.937277 888.4745 Eukaryotic translation initiation factor 4 gamma 1 OS=Homo sapiens OX=9606 GN=EIF4G1 PE=1 SV=4 4.21 3730.5 - 1.40E+06 - - - 1.5646 - 2.666 0.596 - 464.7 1 2 0 0.0028 17 0 0 0 2.65E+07 2.82E+07 - - - 5.853 0.9995 221125_WJC_METTL3_EV_vs_WT_F02.22605.22605.2 3.91E-06 26-Dec R.GEAGVPAEFSIWTR[166.11].E "sp|O75369|FLNB_HUMAN,tr|E7EN95|E7EN95_HUMAN,tr|A0A804HK76|A0A804HK76_HUMAN,tr|A0A804HL72|A0A804HL72_HUMAN" 4 1528.755 1.58 21421 22605 2 1528.759097 765.3848 Filamin-B OS=Homo sapiens OX=9606 GN=FLNB PE=1 SV=2 4.53 3730.9 - 874853 - - - 2.7042 - 2.294 0.477 - 284.5 1 2 0 0.0041 14 0 0 0 1.17E+07 7.42E+06 - - - 4.6464 0.9996 221125_WJC_METTL3_EV_vs_WT_F02.22606.22606.2 0.473 14-Sep K.VNLAELFK.G sp|P30044|PRDX5_HUMAN 1 932.5331 1.41 21422 22606 2 932.533474 467.2738 "Peroxiredoxin-5, mitochondrial OS=Homo sapiens OX=9606 GN=PRDX5 PE=1 SV=4" 5.97 3731 - 845597 - - - 0.3818 - 1.963 0.309 - 276.2 1 2 0 0.0004 8 0 0 0 8.45E+06 6.01E+06 - - - 3.3573 1 221125_WJC_METTL3_EV_vs_WT_F02.22607.22607.3 4.55E-07 14/48 R.SIQLDGLVWGASK[136.11].L "sp|P29692|EF1D_HUMAN,tr|A0A087X1X7|A0A087X1X7_HUMAN,tr|E9PQZ1|E9PQZ1_HUMAN,tr|E9PQC9|E9PQC9_HUMAN,tr|E9PRY8|E9PRY8_HUMAN,tr|E9PK01|E9PK01_HUMAN,tr|H0YE58|H0YE58_HUMAN" 7 1380.7493 1.36 21423 22607 3 1380.751323 461.257 Elongation factor 1-delta OS=Homo sapiens OX=9606 GN=EEF1D PE=1 SV=5 5.55 3731.1 - 729004 - - - 1.4905 - 2.745 0.49 - 350.7 1 2 0 0.0021 13 0 0 0 5.28E+06 3.89E+06 - - - 6.7403 0.9998 221125_WJC_METTL3_EV_vs_WT_F02.22608.22608.2 0.00153 14-Aug K.VNLAELFK[136.11].G sp|P30044|PRDX5_HUMAN 1 940.5473 1.41 21424 22608 2 940.546857 471.2809 "Peroxiredoxin-5, mitochondrial OS=Homo sapiens OX=9606 GN=PRDX5 PE=1 SV=4" 5.97 3731.2 - 602131 - - - -0.4901 - 1.781 0.42 - 191.7 1 2 0 -0.0005 8 0 0 0 8.45E+06 6.01E+06 - - - 3.8837 1 221125_WJC_METTL3_EV_vs_WT_F02.22614.22614.3 1.55E-10 18/64 R.FVDHVFDEQVIDSLTVK.L "sp|P04843|RPN1_HUMAN,tr|B7Z4L4|B7Z4L4_HUMAN" 2 1990.0048 1.33 21428 22614 3 1990.009855 664.3422 Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit 1 OS=Homo sapiens OX=9606 GN=RPN1 PE=1 SV=1 4.22 3731.9 - 8.09E+06 - - - 2.5613 - 3.47 0.54 - 529.2 1 2 0 0.0051 17 0 0 0 5.42E+07 4.07E+07 - - - 7.7022 1 221125_WJC_METTL3_EV_vs_WT_F02.22615.22615.3 7.40E-07 16/64 R.FVDHVFDEQVIDSLTVK[136.11].L "sp|P04843|RPN1_HUMAN,tr|B7Z4L4|B7Z4L4_HUMAN" 2 1998.019 1.47 21429 22615 3 1998.023561 667.0136 Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit 1 OS=Homo sapiens OX=9606 GN=RPN1 PE=1 SV=1 4.22 3732 - 6.75E+06 - - - 2.3038 - 3.493 0.565 - 481.6 1 2 0 0.0046 17 0 0 0 5.97E+07 4.07E+07 - - - 7.9977 0.9732 221125_WJC_METTL3_EV_vs_WT_F02.22617.22617.2 0.000302 24-Nov R.IQEIIEQLDVTTS.E "sp|P10809|CH60_HUMAN,tr|A0A7I2V2X6|A0A7I2V2X6_HUMAN,tr|A0A7I2YQK6|A0A7I2YQK6_HUMAN,tr|A0A7I2V599|A0A7I2V599_HUMAN" 4 1487.7719 - 21431 22617 2 1487.774955 744.8932 "60 kDa heat shock protein, mitochondrial OS=Homo sapiens OX=9606 GN=HSPD1 PE=1 SV=2" 3.57 3732.1 - 4.38E+06 - - - 2.05 - 2.099 0.433 - 420.1 1 1 0 0.0031 13 0 0 0 - - - - - 4.1412 1 221125_WJC_METTL3_EV_vs_WT_F02.22618.22618.2 0.000134 13/20 K.LENLFEALNNK.N sp|P31944|CASPE_HUMAN 1 1303.6772 999 21432 22618 2 1303.681239 652.8459 Caspase-14 OS=Homo sapiens OX=9606 GN=CASP14 PE=1 SV=2 4.53 3732.1 - 3.20E+06 - - - 3.0859 - 2.82 0.535 - 847.5 1 2 0 0.004 11 0 0 0 4.83E+07 0.00E+00 - - - 5.7959 0.9996 221125_WJC_METTL3_EV_vs_WT_F02.22621.22621.2 1.08E-06 26-Nov K.SESVPPVTDWAWYK.L "sp|P35613|BASI_HUMAN,tr|A0A7P0T8A7|A0A7P0T8A7_HUMAN,tr|A0A087WUV8|A0A087WUV8_HUMAN,tr|A0A7P0TA85|A0A7P0TA85_HUMAN,tr|A0A7P0TB04|A0A7P0TB04_HUMAN,tr|R4GMX5|R4GMX5_HUMAN,tr|R4GN83|R4GN83_HUMAN,tr|I3L192|I3L192_HUMAN" 8 1663.7882 1.72 21435 22621 2 1663.792677 832.9014 Basigin OS=Homo sapiens OX=9606 GN=BSG PE=1 SV=2 4.37 3732.4 - 1.75E+06 - - - 2.677 - 2.191 0.561 - 243.4 1 2 0 0.0045 14 0 0 0 5.14E+07 3.00E+07 - - - 5.1515 0.999 221125_WJC_METTL3_EV_vs_WT_F02.22622.22622.2 4.64E-07 26-Oct K.SESVPPVTDWAWYK[136.11].L "sp|P35613|BASI_HUMAN,tr|A0A7P0T8A7|A0A7P0T8A7_HUMAN,tr|A0A087WUV8|A0A087WUV8_HUMAN,tr|A0A7P0TA85|A0A7P0TA85_HUMAN,tr|A0A7P0TB04|A0A7P0TB04_HUMAN,tr|R4GMX5|R4GMX5_HUMAN,tr|R4GN83|R4GN83_HUMAN,tr|I3L192|I3L192_HUMAN" 8 1671.8024 1.67 21436 22622 2 1671.808698 836.9085 Basigin OS=Homo sapiens OX=9606 GN=BSG PE=1 SV=2 4.37 3732.5 - 1.43E+06 - - - 3.7534 - 1.947 0.547 - 236.3 1 2 0 0.0063 14 0 0 0 5.00E+07 3.00E+07 - - - 4.7512 1 221125_WJC_METTL3_EV_vs_WT_F02.22623.22623.3 1.17E-13 22/84 K.VALIGSPVDLTYTYDHLGDSPK.L "sp|P28331|NDUS1_HUMAN,tr|B4DJ81|B4DJ81_HUMAN" 2 2360.19 1.2 21437 22623 3 2360.195944 787.7373 "NADH-ubiquinone oxidoreductase 75 kDa subunit, mitochondrial OS=Homo sapiens OX=9606 GN=NDUFS1 PE=1 SV=3" 4.41 3732.6 - 1.37E+06 - - - 2.5214 - 4.491 0.613 - 603.2 1 2 0 0.006 22 0 0 0 4.69E+06 3.91E+06 - - - 8.9339 1 221125_WJC_METTL3_EV_vs_WT_F02.22625.22625.3 3.59E-05 17/64 R.SVSIPAPAYYAHLVAFR.A "sp|Q9UKV8|AGO2_HUMAN,sp|Q9H9G7|AGO3_HUMAN" 2 1860.9887 1.39 21439 22625 3 1860.993277 621.3368 Protein argonaute-2 OS=Homo sapiens OX=9606 GN=AGO2 PE=1 SV=3 8.33 3732.8 - 763143 - - - 2.4842 - 3.274 0.511 - 379.4 1 2 0 0.0046 17 0 0 0 6.65E+06 4.78E+06 - - - 7.2321 1 221125_WJC_METTL3_EV_vs_WT_F02.22626.22626.2 2.70E-08 24-Dec R.EAGQC[160.03]FESFLVVR[166.11].G sp|Q9HCE1|MOV10_HUMAN 1 1550.7427 -1 21440 22626 2 1550.746475 776.3786 Helicase MOV-10 OS=Homo sapiens OX=9606 GN=MOV10 PE=1 SV=2 4.53 3732.9 - 706807 - - - 2.4446 - 2.72 0.6 - 629.4 1 2 0 0.0038 13 0 0 0 0.00E+00 0.00E+00 - - - 6.0396 1 221125_WJC_METTL3_EV_vs_WT_F02.22627.22627.2 3.36E-06 16/28 R.VLEAETQILTDWQDK[136.11].K "sp|O75528|TADA3_HUMAN,tr|C9JMS0|C9JMS0_HUMAN" 2 1795.9083 1.53 21441 22627 2 1795.912011 898.9614 Transcriptional adapter 3 OS=Homo sapiens OX=9606 GN=TADA3 PE=1 SV=1 3.92 3733.1 - 601660 - - - 2.0413 - 3.298 0.603 - 814 1 2 0 0.0037 15 0 0 0 7.02E+06 4.60E+06 - - - 6.4274 0.9996 221125_WJC_METTL3_EV_vs_WT_F02.22628.22628.2 5.89E-05 30-Nov R.IAVMSFPAEGVESALK[136.11].N sp|O14976|GAK_HUMAN 1 1655.8684 -1 21442 22628 2 1655.870216 828.9415 Cyclin-G-associated kinase OS=Homo sapiens OX=9606 GN=GAK PE=1 SV=2 4.53 3733.2 - 466785 - - - 1.1003 - 2.287 0.338 - 239.8 1 2 0 0.0018 16 0 0 0 0.00E+00 0.00E+00 - - - 3.5707 0.9994 221125_WJC_METTL3_EV_vs_WT_F02.22629.22629.2 2.39E-05 30-Dec K.YVVQNPEQEPLSQFLR.G sp|Q8WVV4|POF1B_HUMAN 1 1945.9898 999 21443 22629 2 1945.989449 974.0022 Protein POF1B OS=Homo sapiens OX=9606 GN=POF1B PE=1 SV=3 4.53 3733.3 - 457543 - - - -0.1686 - 2.655 0.189 - 332.7 1 2 0 -0.0003 16 0 0 0 3.78E+06 0.00E+00 - - - 2.8375 1 221125_WJC_METTL3_EV_vs_WT_F02.22632.22632.2 9.51E-15 19/32 R.FVDHVFDEQVIDSLTVK.L "sp|P04843|RPN1_HUMAN,tr|B7Z4L4|B7Z4L4_HUMAN" 2 1990.0048 -1 21446 22632 2 1990.007632 996.0097 Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit 1 OS=Homo sapiens OX=9606 GN=RPN1 PE=1 SV=1 4.22 3733.7 - 334272 - - - 1.4442 - 3.935 0.71 - 1227.6 1 2 0 0.0029 17 0 0 0 0.00E+00 0.00E+00 - - - 7.6521 0.9997 221125_WJC_METTL3_EV_vs_WT_F02.22636.22636.2 0.000252 13/30 R.LFVGNLPPDITEEEMR[166.11].K "sp|Q15233|NONO_HUMAN,tr|A0A7I2V535|A0A7I2V535_HUMAN,tr|A0A7I2V4N2|A0A7I2V4N2_HUMAN,tr|A0A7I2V4K9|A0A7I2V4K9_HUMAN,tr|A0A7I2V464|A0A7I2V464_HUMAN,tr|A0A7P0MRW0|A0A7P0MRW0_HUMAN,tr|C9IZL7|C9IZL7_HUMAN,tr|C9J4X2|C9J4X2_HUMAN,tr|A0A7I2YQK8|A0A7I2YQK8_HUMAN,tr|A0A7I2V4J2|A0A7I2V4J2_HUMAN,tr|A0A7I2V5Y7|A0A7I2V5Y7_HUMAN,tr|C9JYS8|C9JYS8_HUMAN" 12 1868.9218 1.64 21449 22636 2 1868.919231 935.4682 Non-POU domain-containing octamer-binding protein OS=Homo sapiens OX=9606 GN=NONO PE=1 SV=4 4 3734.2 - 317397 - - - -1.3585 - 2.17 0.425 - 328.7 1 2 0 -0.0025 16 0 0 0 3.82E+06 2.32E+06 - - - 4.084 0.9996 221125_WJC_METTL3_EV_vs_WT_F02.22638.22638.2 1.28E-08 13/22 R.VDELTTDLEILK.A "sp|Q14203|DCTN1_HUMAN,tr|A0A804CDA6|A0A804CDA6_HUMAN,tr|E7EX90|E7EX90_HUMAN,tr|A0A7P0Z4C3|A0A7P0Z4C3_HUMAN,tr|Q6AWB1|Q6AWB1_HUMAN" 5 1387.7446 2.16 21451 22638 2 1387.748352 694.8796 Dynactin subunit 1 OS=Homo sapiens OX=9606 GN=DCTN1 PE=1 SV=3 3.92 3734.3 - 7.16E+06 - - - 2.6842 - 2.862 0.447 - 692.9 1 2 0 0.0037 12 0 0 0 1.05E+08 4.87E+07 - - - 5.1081 1 221125_WJC_METTL3_EV_vs_WT_F02.22639.22639.3 6.00E-08 17/52 K.DVYVQLYLQHLTAR.N "sp|P42166|LAP2A_HUMAN,sp|P42167|LAP2B_HUMAN,tr|G5E972|G5E972_HUMAN" 3 1717.9152 1.08 21452 22639 3 1717.918586 573.6457 "Lamina-associated polypeptide 2, isoform alpha OS=Homo sapiens OX=9606 GN=TMPO PE=1 SV=2" 6.74 3734.3 - 4.93E+06 - - - 1.9972 - 2.824 0.501 - 323.5 1 2 0 0.0034 14 0 0 0 3.54E+07 3.28E+07 - - - 6.8836 1 221125_WJC_METTL3_EV_vs_WT_F02.22640.22640.3 3.92E-09 21/96 K.IVSLFAEHNDLQYAAPGGLIGVGTK[136.11].L "sp|Q2VIR3|IF2GL_HUMAN,sp|P41091|IF2G_HUMAN" 2 2577.3682 0.35 21453 22640 3 2577.370924 860.13 Eukaryotic translation initiation factor 2 subunit 3B OS=Homo sapiens OX=9606 GN=EIF2S3B PE=2 SV=2 5.32 3734.4 - 2.77E+06 - - - 1.0421 - 3.133 0.525 - 299.7 1 2 0 0.0027 25 0 0 0 3.32E+06 9.43E+06 - - - 7.0198 0.957 221125_WJC_METTL3_EV_vs_WT_F02.22642.22642.2 1.20E-05 20-Oct S.STMMEVFLQEK.S "sp|Q14157|UBP2L_HUMAN,tr|F8W726|F8W726_HUMAN" 2 1341.6309 1.97 21455 22642 2 1341.635512 671.8227 Ubiquitin-associated protein 2-like OS=Homo sapiens OX=9606 GN=UBAP2L PE=1 SV=2 4.53 3734.5 - 1.90E+06 - - - 3.4674 - 2.165 0.515 - 343.3 1 1 0 0.0047 11 0 0 0 1.59E+07 8.10E+06 - - - 4.9329 0.9996 221125_WJC_METTL3_EV_vs_WT_F02.22643.22643.3 0.000642 Nov-52 R.GWDENVYYTVPLVR.H sp|Q9BPW8|NIPS1_HUMAN 1 1709.8413 1.14 21456 22643 3 1709.844927 570.9544 Protein NipSnap homolog 1 OS=Homo sapiens OX=9606 GN=NIPSNAP1 PE=1 SV=1 4.37 3734.6 - 1.80E+06 - - - 2.1084 - 1.971 0.376 - 136.3 1 2 0 0.0036 14 0 0 0 8.31E+06 7.26E+06 - - - 4.5343 1 221125_WJC_METTL3_EV_vs_WT_F02.22645.22645.2 1.19E-09 24/36 K.ILTATVDNANVLLQIDNAR.L sp|P02533|K1C14_HUMAN 1 2053.1168 999 21458 22645 2 2053.119147 1027.5657 "Keratin, type I cytoskeletal 14 OS=Homo sapiens OX=9606 GN=KRT14 PE=1 SV=4" 4.21 3734.8 - 1.57E+06 - - - 1.1587 - 4.296 0.653 - 2142.5 1 2 0 0.0024 19 0 0 0 5.37E+08 0.00E+00 - - - 7.4471 0.9996 221125_WJC_METTL3_EV_vs_WT_F02.22647.22647.3 0.000338 14/44 R.FKEANNFLWPFK.L "sp|P18124|RL7_HUMAN,tr|A8MUD9|A8MUD9_HUMAN" 2 1539.7874 0.68 21460 22647 3 1539.790515 514.2698 60S ribosomal protein L7 OS=Homo sapiens OX=9606 GN=RPL7 PE=1 SV=1 8.59 3734.9 - 1.53E+06 - - - 2.0003 - 2.118 0.473 - 192.8 1 2 1 0.0031 12 0 0 0 1.28E+07 1.87E+07 - - - 5.8928 1 221125_WJC_METTL3_EV_vs_WT_F02.22648.22648.2 1.47E-09 19/28 R.VLEAETQILTDWQDK.K "sp|O75528|TADA3_HUMAN,tr|C9JMS0|C9JMS0_HUMAN" 2 1787.8941 1.53 21461 22648 2 1787.896916 894.9543 Transcriptional adapter 3 OS=Homo sapiens OX=9606 GN=TADA3 PE=1 SV=1 3.92 3735.1 - 1.48E+06 - - - 1.5499 - 3.803 0.62 - 1346.6 1 2 0 0.0028 15 0 0 0 7.02E+06 4.60E+06 - - - 6.9036 0.9996 221125_WJC_METTL3_EV_vs_WT_F02.22649.22649.3 5.41E-05 Dec-56 K.DLYIDRPLPYLIGSK.L "sp|Q641Q2|WAC2A_HUMAN,sp|Q9Y4E1|WAC2C_HUMAN,tr|F8W7U3|F8W7U3_HUMAN,tr|J3KP36|J3KP36_HUMAN,tr|E7ESD2|E7ESD2_HUMAN,tr|A0A0A0MT65|A0A0A0MT65_HUMAN,tr|A0A0A0MR88|A0A0A0MR88_HUMAN,tr|A0A087WYF6|A0A087WYF6_HUMAN,tr|A0A096LPC5|A0A096LPC5_HUMAN" 9 1761.9665 2.46 21462 22649 3 1761.970102 588.3295 WASH complex subunit 2A OS=Homo sapiens OX=9606 GN=WASHC2A PE=1 SV=3 5.96 3735.1 - 1.27E+06 - - - 2.0318 - 1.974 0.381 - 92.6 1 2 0 0.0036 15 0 0 0 5.52E+06 2.24E+06 - - - 4.5613 0.9998 221125_WJC_METTL3_EV_vs_WT_F02.22650.22650.2 0.000121 18-Sep K.EELEFEVPFR.D sp|Q9Y5B9|SP16H_HUMAN 1 1293.6241 1.81 21463 22650 2 1293.625572 647.8193 FACT complex subunit SPT16 OS=Homo sapiens OX=9606 GN=SUPT16H PE=1 SV=1 4.09 3735.2 - 1.23E+06 - - - 1.124 - 1.968 0.463 - 413.8 1 2 0 0.0015 10 0 0 0 1.23E+07 6.79E+06 - - - 4.35 0.9999 221125_WJC_METTL3_EV_vs_WT_F02.22652.22652.3 0.00322 17/60 R.ELFLTAGGAGGLHLWK.Y "sp|Q96MX6|DAA10_HUMAN,tr|Q8ND98|Q8ND98_HUMAN,tr|H7C389|H7C389_HUMAN" 3 1668.8988 1.4 21465 22652 3 1668.903869 557.3069 Dynein axonemal assembly factor 10 OS=Homo sapiens OX=9606 GN=DNAAF10 PE=1 SV=1 6.85 3735.4 - 931720 - - - 3.0511 - 3.206 0.43 - 233.3 1 2 0 0.0051 16 0 0 0 5.49E+06 3.91E+06 - - - 6.322 1 221125_WJC_METTL3_EV_vs_WT_F02.22653.22653.3 1.23E-06 Nov-40 R.LHQLLALTLWK.E "sp|Q7L5D6|GET4_HUMAN,tr|C9JPA8|C9JPA8_HUMAN,tr|C9JHN8|C9JHN8_HUMAN,tr|C9JY46|C9JY46_HUMAN" 4 1334.8074 1.93 21466 22653 3 1334.810592 445.9431 Golgi to ER traffic protein 4 homolog OS=Homo sapiens OX=9606 GN=GET4 PE=1 SV=1 8.76 3735.5 - 814426 - - - 2.3591 - 2.537 0.537 - 239.2 1 2 0 0.0031 11 0 0 0 5.43E+06 2.82E+06 - - - 7.1709 1 221125_WJC_METTL3_EV_vs_WT_F02.22656.22656.3 1.30E-05 Oct-40 R.LHQLLALTLWK[136.11].E "sp|Q7L5D6|GET4_HUMAN,tr|C9JPA8|C9JPA8_HUMAN,tr|C9JHN8|C9JHN8_HUMAN,tr|C9JY46|C9JY46_HUMAN" 4 1342.8216 1.86 21468 22656 3 1342.822746 448.6145 Golgi to ER traffic protein 4 homolog OS=Homo sapiens OX=9606 GN=GET4 PE=1 SV=1 8.76 3736 - 778794 - - - 0.8214 - 2.332 0.473 - 252.8 1 2 0 0.0011 11 0 0 0 5.23E+06 2.82E+06 - - - 6.2186 0.9992 221125_WJC_METTL3_EV_vs_WT_F02.22657.22657.3 0.0246 Aug-40 K.LENLFEALNNK.N sp|P31944|CASPE_HUMAN 1 1303.6772 999 21469 22657 3 1303.67914 435.5663 Caspase-14 OS=Homo sapiens OX=9606 GN=CASP14 PE=1 SV=2 4.53 3736.1 - 583546 - - - 1.4758 - 1.845 0.308 - 63.2 1 2 0 0.0019 11 0 0 0 2.13E+06 0.00E+00 - - - 3.7133 1 221125_WJC_METTL3_EV_vs_WT_F02.22658.22658.3 2.22E-06 19/72 K.ILTATVDNANVLLQIDNAR.L sp|P02533|K1C14_HUMAN 1 2053.1168 999 21470 22658 3 2053.119197 685.3795 "Keratin, type I cytoskeletal 14 OS=Homo sapiens OX=9606 GN=KRT14 PE=1 SV=4" 4.21 3736.1 - 6.82E+07 - - - 1.1831 - 3.546 0.613 - 413.2 1 2 0 0.0024 19 0 0 0 2.17E+09 0.00E+00 - - - 8.4835 1 221125_WJC_METTL3_EV_vs_WT_F02.22661.22661.3 2.10E-08 18/52 R.HLGLVPLEPGGWLR[166.11].R "sp|O14654|IRS4_HUMAN,tr|A0A804CF45|A0A804CF45_HUMAN" 2 1552.8754 0.83 21473 22661 3 1552.877224 518.6324 Insulin receptor substrate 4 OS=Homo sapiens OX=9606 GN=IRS4 PE=1 SV=1 6.75 3736.3 - 2.81E+06 - - - 1.2049 - 3.417 0.628 - 529.3 1 2 0 0.0019 14 0 0 0 2.10E+07 2.54E+07 - - - 8.8065 1 221125_WJC_METTL3_EV_vs_WT_F02.22662.22662.3 2.61E-10 19/72 R.SVLLLAYK[136.11]PMEGNFEEIAR[166.11].D "sp|Q16531|DDB1_HUMAN,tr|A0A7P0TAK7|A0A7P0TAK7_HUMAN,tr|A0A7P0T870|A0A7P0T870_HUMAN,tr|A0A7P0TB30|A0A7P0TB30_HUMAN,tr|A0A7P0Z3Z5|A0A7P0Z3Z5_HUMAN,tr|F5GY55|F5GY55_HUMAN,tr|A0A7P0Z4B9|A0A7P0Z4B9_HUMAN,tr|A0A7P0T965|A0A7P0T965_HUMAN" 8 2197.1572 -1 21474 22662 3 2197.157189 733.393 DNA damage-binding protein 1 OS=Homo sapiens OX=9606 GN=DDB1 PE=1 SV=1 4.78 3736.3 - 2.79E+06 - - - -0.0032 - 3.462 0.602 - 390.9 1 2 0 0 19 0 0 0 0.00E+00 0.00E+00 - - - 8.3027 1 221125_WJC_METTL3_EV_vs_WT_F02.22664.22664.3 4.14E-06 13/52 R.HLGLVPLEPGGWLR.R "sp|O14654|IRS4_HUMAN,tr|A0A804CF45|A0A804CF45_HUMAN" 2 1542.8671 0.81 21476 22664 3 1542.867344 515.2963 Insulin receptor substrate 4 OS=Homo sapiens OX=9606 GN=IRS4 PE=1 SV=1 6.75 3736.5 - 2.05E+06 - - - 0.1692 - 2.806 0.56 - 239.4 1 2 0 0.0003 14 0 0 0 2.06E+07 2.54E+07 - - - 7.5253 0.9894 221125_WJC_METTL3_EV_vs_WT_F02.22666.22666.3 0.0932 16/60 K.LSEIPLTLHSVSELVR.L sp|Q9UIG0|BAZ1B_HUMAN 1 1792.0095 0.93 21478 22666 3 1792.02071 598.3438 Tyrosine-protein kinase BAZ1B OS=Homo sapiens OX=9606 GN=BAZ1B PE=1 SV=2 5.4 3736.6 - 1.46E+06 - - - 6.2834 - 2.631 0.294 - 276.5 1 2 0 0.0113 16 0 0 0 1.46E+07 1.57E+07 - - - 4.2968 1 221125_WJC_METTL3_EV_vs_WT_F02.22668.22668.3 8.29E-06 15/56 R.VVNQLLTEMDGLEAR.Q sp|O15381|NVL_HUMAN 1 1686.8611 0.96 21480 22668 3 1686.863382 563.2943 Nuclear valosin-containing protein-like OS=Homo sapiens OX=9606 GN=NVL PE=1 SV=1 4.14 3736.9 - 782516 - - - 1.37 - 2.418 0.493 - 296 1 2 0 0.0023 15 0 0 0 4.07E+06 4.22E+06 - - - 6.3397 0.9999 221125_WJC_METTL3_EV_vs_WT_F02.22670.22670.3 1.07E-05 Dec-48 K.LYGLLDPSVFHVK[136.11].Y sp|Q9BVI4|NOC4L_HUMAN 1 1494.8326 0.79 21482 22670 3 1494.832312 499.2848 Nucleolar complex protein 4 homolog OS=Homo sapiens OX=9606 GN=NOC4L PE=1 SV=1 6.74 3737.1 - 757059 - - - -0.1933 - 2.367 0.449 - 148.8 1 2 0 -0.0003 13 0 0 0 4.38E+06 5.55E+06 - - - 5.8819 0.9999 221125_WJC_METTL3_EV_vs_WT_F02.22671.22671.2 7.15E-06 22-Nov K.DFQAIADVIGNK.T "sp|Q9P2K3|RCOR3_HUMAN,tr|H0YF22|H0YF22_HUMAN" 2 1289.6616 -1 21483 22671 2 1289.660484 645.8381 REST corepressor 3 OS=Homo sapiens OX=9606 GN=RCOR3 PE=1 SV=2 4.21 3737.2 - 675060 - - - -0.839 - 2.206 0.554 - 320.1 1 2 0 -0.0011 12 0 0 0 0.00E+00 0.00E+00 - - - 5.2142 0.9997 221125_WJC_METTL3_EV_vs_WT_F02.22673.22673.3 9.29E-05 Sep-48 K.LYGLLDPSVFHVK.Y sp|Q9BVI4|NOC4L_HUMAN 1 1486.8184 0.62 21485 22673 3 1486.820544 496.6134 Nucleolar complex protein 4 homolog OS=Homo sapiens OX=9606 GN=NOC4L PE=1 SV=1 6.74 3737.5 - 514870 - - - 1.4413 - 2.142 0.347 - 80.6 1 2 0 0.0021 13 0 0 0 4.38E+06 7.02E+06 - - - 4.4734 0.9999 221125_WJC_METTL3_EV_vs_WT_F02.22680.22680.2 0.00343 16-Sep K.DAEEWFFTK.T sp|P02533|K1C14_HUMAN 1 1171.5186 3316.05 21490 22680 2 1171.518831 586.7666 "Keratin, type I cytoskeletal 14 OS=Homo sapiens OX=9606 GN=KRT14 PE=1 SV=4" 4.14 3738.2 - 2.17E+07 - - - 0.2057 - 2.088 0.464 - 339.5 1 2 0 0.0002 9 0 0 0 3.17E+09 9.56E+05 - - - 4.5979 0.9999 221125_WJC_METTL3_EV_vs_WT_F02.22682.22682.2 2.11E-08 15/28 R.APGPWDPLASAAGLK.E "sp|O75190|DNJB6_HUMAN,tr|E9PH18|E9PH18_HUMAN" 2 1449.7616 1.03 21492 22682 2 1449.762435 725.8881 DnaJ homolog subfamily B member 6 OS=Homo sapiens OX=9606 GN=DNAJB6 PE=1 SV=2 5.88 3738.3 - 3.22E+06 - - - 0.5656 - 2.551 0.584 - 594.1 1 2 0 0.0008 15 0 0 0 3.56E+07 3.45E+07 - - - 5.6566 0.9998 221125_WJC_METTL3_EV_vs_WT_F02.22683.22683.2 2.42E-06 13/28 R.QGIVPPGLTENELWR[166.11].A "sp|Q9H9B4|SFXN1_HUMAN,tr|D6RFI0|D6RFI0_HUMAN,tr|D6RDG7|D6RDG7_HUMAN,tr|S4R2X2|S4R2X2_HUMAN" 4 1717.9027 0.86 21493 22683 2 1717.905473 859.9586 Sideroflexin-1 OS=Homo sapiens OX=9606 GN=SFXN1 PE=1 SV=4 4.53 3738.4 - 3.08E+06 - - - 1.62 - 2.344 0.544 - 387.9 1 2 0 0.0028 15 0 0 0 2.28E+07 2.67E+07 - - - 5.1524 0.9984 221125_WJC_METTL3_EV_vs_WT_F02.22685.22685.2 0.235 18-Oct K.ILLAELEQLK[136.11].G "sp|P08670|VIME_HUMAN,tr|B0YJC4|B0YJC4_HUMAN,tr|A0A1B0GTT5|A0A1B0GTT5_HUMAN" 3 1176.7209 1.95 21495 22685 2 1176.721274 589.3677 Vimentin OS=Homo sapiens OX=9606 GN=VIM PE=1 SV=4 4.53 3738.5 - 2.48E+06 - - - 0.2966 - 1.671 0.208 - 220.1 1 2 0 0.0003 10 0 0 0 1.00E+08 5.12E+07 - - - 2.0103 0.9998 221125_WJC_METTL3_EV_vs_WT_F02.22686.22686.2 1.67E-05 20-Dec R.AWDDFFPGSDR.F "sp|O75915|PRAF3_HUMAN,tr|F8WF33|F8WF33_HUMAN,tr|F8WF90|F8WF90_HUMAN,tr|C9JQU6|C9JQU6_HUMAN" 4 1311.552 0.92 21496 22686 2 1311.554091 656.7833 PRA1 family protein 3 OS=Homo sapiens OX=9606 GN=ARL6IP5 PE=1 SV=1 3.93 3738.6 - 2.24E+06 - - - 1.5821 - 2.241 0.583 - 568.3 1 2 0 0.0021 11 0 0 0 2.35E+07 2.56E+07 - - - 5.5293 0.9998 221125_WJC_METTL3_EV_vs_WT_F02.22687.22687.2 0.0052 13/24 R.LAALPNVYEVISK[136.11].S "sp|P33992|MCM5_HUMAN,tr|B1AHB1|B1AHB1_HUMAN" 2 1423.8166 0.1 21497 22687 2 1423.815821 712.9156 DNA replication licensing factor MCM5 OS=Homo sapiens OX=9606 GN=MCM5 PE=1 SV=5 6 3738.7 - 2.18E+06 - - - -0.5591 - 2.371 0.392 - 466.1 1 2 0 -0.0008 13 0 0 0 3.94E+06 3.97E+07 - - - 4.1518 1 221125_WJC_METTL3_EV_vs_WT_F02.22689.22689.3 3.37E-07 26/80 K.DLYANTVLSGGTTMYPGIADR.M "sp|P63261|ACTG_HUMAN,sp|P60709|ACTB_HUMAN,tr|A0A804GS07|A0A804GS07_HUMAN,tr|E7EVS6|E7EVS6_HUMAN,tr|A0A6Q8PFE4|A0A6Q8PFE4_HUMAN,tr|A0A2R8Y793|A0A2R8Y793_HUMAN,tr|I3L4N8|I3L4N8_HUMAN" 7 2214.0627 1.03 21499 22689 3 2214.063447 739.0282 "Actin, cytoplasmic 2 OS=Homo sapiens OX=9606 GN=ACTG1 PE=1 SV=1" 4.21 3738.9 - 1.77E+06 - - - 0.3446 - 3.572 0.588 - 558.1 1 2 0 0.0008 21 0 0 0 2.22E+08 2.15E+08 - - - 8.1477 0.9978 221125_WJC_METTL3_EV_vs_WT_F02.22691.22691.3 0.00221 13/60 K.LSEIPLTLHSVSELVR[166.11].L sp|Q9UIG0|BAZ1B_HUMAN 1 1802.0177 1.71 21501 22691 3 1802.026135 601.6798 Tyrosine-protein kinase BAZ1B OS=Homo sapiens OX=9606 GN=BAZ1B PE=1 SV=2 5.4 3739.1 - 1.47E+06 - - - 4.6698 - 2.46 0.347 - 181.6 1 2 0 0.0084 16 0 0 0 9.78E+06 5.72E+06 - - - 4.7161 1 221125_WJC_METTL3_EV_vs_WT_F02.22693.22693.2 9.62E-15 23/36 R.YEGILYTIDTENSTVALAK.V "sp|Q8ND56|LS14A_HUMAN,tr|I3L4Q1|I3L4Q1_HUMAN,tr|A0A140TA76|A0A140TA76_HUMAN,tr|K7EMZ9|K7EMZ9_HUMAN" 4 2100.0627 1.2 21503 22693 2 2100.063914 1051.0386 Protein LSM14 homolog A OS=Homo sapiens OX=9606 GN=LSM14A PE=1 SV=3 4.14 3739.4 - 1.38E+06 - - - 0.5938 - 4.035 0.683 - 1404.7 1 2 0 0.0012 19 0 0 0 1.56E+09 1.30E+09 - - - 7.5149 0.9999 221125_WJC_METTL3_EV_vs_WT_F02.22696.22696.2 7.71E-07 13/28 K.VLSVPESTPFTAVLK.F "sp|P61960|UFM1_HUMAN,tr|H0Y614|H0Y614_HUMAN" 2 1586.892 1.48 21506 22696 2 1586.891816 794.4533 Ubiquitin-fold modifier 1 OS=Homo sapiens OX=9606 GN=UFM1 PE=1 SV=1 5.97 3739.7 - 1.07E+06 - - - -0.0907 - 2.127 0.53 - 352.6 1 2 0 -0.0001 15 0 0 0 7.89E+06 5.31E+06 - - - 4.811 1 221125_WJC_METTL3_EV_vs_WT_F02.22701.22701.3 3.86E-08 17/56 K.GLASWDEGHVLTFLK.Q sp|Q6ZRP7|QSOX2_HUMAN 1 1671.8621 1.13 21510 22701 3 1671.865337 558.2946 Sulfhydryl oxidase 2 OS=Homo sapiens OX=9606 GN=QSOX2 PE=1 SV=3 5.32 3740.2 - 5.27E+06 - - - 1.9619 - 3.385 0.588 - 260 1 2 0 0.0033 15 0 0 0 1.47E+07 1.30E+07 - - - 8.2765 1 221125_WJC_METTL3_EV_vs_WT_F02.22702.22702.3 3.16E-09 18/72 R.YEGILYTIDTENSTVALAK.V "sp|Q8ND56|LS14A_HUMAN,tr|I3L4Q1|I3L4Q1_HUMAN,tr|A0A140TA76|A0A140TA76_HUMAN,tr|K7EMZ9|K7EMZ9_HUMAN" 4 2100.0627 1.04 21511 22702 3 2100.060953 701.0282 Protein LSM14 homolog A OS=Homo sapiens OX=9606 GN=LSM14A PE=1 SV=3 4.14 3740.3 - 3.39E+07 - - - -0.8162 - 3.487 0.657 - 526.6 1 2 0 -0.0017 19 0 0 0 1.53E+09 1.48E+09 - - - 8.9331 1 221125_WJC_METTL3_EV_vs_WT_F02.22704.22704.3 3.95E-09 23/80 K.DLYANTVLSGGTTMYPGIADR[166.11].M "sp|P63261|ACTG_HUMAN,sp|P60709|ACTB_HUMAN,tr|A0A804GS07|A0A804GS07_HUMAN,tr|E7EVS6|E7EVS6_HUMAN,tr|A0A6Q8PFE4|A0A6Q8PFE4_HUMAN,tr|A0A2R8Y793|A0A2R8Y793_HUMAN,tr|I3L4N8|I3L4N8_HUMAN" 7 2224.071 1.03 21513 22704 3 2224.069498 742.3643 "Actin, cytoplasmic 2 OS=Homo sapiens OX=9606 GN=ACTG1 PE=1 SV=1" 4.21 3740.4 - 1.34E+07 - - - -0.6547 - 3.826 0.613 - 415.8 1 2 0 -0.0015 21 0 0 0 2.22E+08 2.15E+08 - - - 8.5909 1 221125_WJC_METTL3_EV_vs_WT_F02.22708.22708.2 9.00E-11 17/28 R.TVYFSEQWVSSLNER.E "sp|P52732|KIF11_HUMAN,tr|A0A7I2V3A9|A0A7I2V3A9_HUMAN" 2 1843.8741 5.43 21517 22708 2 1843.870845 922.9443 Kinesin-like protein KIF11 OS=Homo sapiens OX=9606 GN=KIF11 PE=1 SV=2 4.53 3740.5 - 6.80E+06 - - - -1.7534 - 3.139 0.69 - 1090 1 2 0 -0.0032 15 0 0 0 1.60E+08 2.94E+07 - - - 6.9487 1 221125_WJC_METTL3_EV_vs_WT_F02.22709.22709.3 3.20E-08 14/56 R.TVYFSEQWVSSLNER.E "sp|P52732|KIF11_HUMAN,tr|A0A7I2V3A9|A0A7I2V3A9_HUMAN" 2 1843.8741 4.67 21518 22709 3 1843.870883 615.632 Kinesin-like protein KIF11 OS=Homo sapiens OX=9606 GN=KIF11 PE=1 SV=2 4.53 3740.6 - 5.67E+06 - - - -1.7328 - 2.816 0.66 - 228.6 1 2 0 -0.0032 15 0 0 0 1.06E+08 2.27E+07 - - - 8.599 0.9999 221125_WJC_METTL3_EV_vs_WT_F02.22710.22710.2 0.000187 13/22 R.LAEISDVWEEMK.T "sp|Q01082|SPTB2_HUMAN,tr|A0A087WUZ3|A0A087WUZ3_HUMAN" 2 1448.6857 2.22 21519 22710 2 1448.685121 725.3501 "Spectrin beta chain, non-erythrocytic 1 OS=Homo sapiens OX=9606 GN=SPTBN1 PE=1 SV=2" 4 3740.6 - 4.76E+06 - - - -0.4218 - 2.679 0.437 - 625.7 1 2 0 -0.0006 12 0 0 0 2.47E+07 1.11E+07 - - - 4.8614 1 221125_WJC_METTL3_EV_vs_WT_F02.22714.22714.2 4.40E-11 18/32 R.LDGLVETPTGYIESLPR.V "sp|P55209|NP1L1_HUMAN,tr|F8VUX1|F8VUX1_HUMAN,tr|F8W118|F8W118_HUMAN,tr|F8VRJ2|F8VRJ2_HUMAN,tr|F8W0J6|F8W0J6_HUMAN,tr|F8VV59|F8VV59_HUMAN,tr|B7Z9C2|B7Z9C2_HUMAN,tr|F8VXI6|F8VXI6_HUMAN,tr|H0YHC3|H0YHC3_HUMAN,tr|H0YIV4|H0YIV4_HUMAN,tr|F5H4R6|F5H4R6_HUMAN,tr|F8W020|F8W020_HUMAN,tr|F8VY35|F8VY35_HUMAN" 13 1858.9676 1.24 21523 22714 2 1858.966209 930.4911 Nucleosome assembly protein 1-like 1 OS=Homo sapiens OX=9606 GN=NAP1L1 PE=1 SV=1 4.14 3740.8 - 4.42E+06 - - - -0.7719 - 3.433 0.553 - 893.7 1 2 0 -0.0014 17 0 0 0 7.98E+07 6.41E+07 - - - 6.1575 0.9999 221125_WJC_METTL3_EV_vs_WT_F02.22715.22715.2 2.97E-07 15/32 R.LDGLVETPTGYIESLPR[166.11].V "sp|P55209|NP1L1_HUMAN,tr|F8VUX1|F8VUX1_HUMAN,tr|F8W118|F8W118_HUMAN,tr|F8VRJ2|F8VRJ2_HUMAN,tr|F8W0J6|F8W0J6_HUMAN,tr|F8VV59|F8VV59_HUMAN,tr|B7Z9C2|B7Z9C2_HUMAN,tr|F8VXI6|F8VXI6_HUMAN,tr|H0YHC3|H0YHC3_HUMAN,tr|H0YIV4|H0YIV4_HUMAN,tr|F5H4R6|F5H4R6_HUMAN,tr|F8W020|F8W020_HUMAN,tr|F8VY35|F8VY35_HUMAN" 13 1868.9759 1.24 21524 22715 2 1868.975373 935.4952 Nucleosome assembly protein 1-like 1 OS=Homo sapiens OX=9606 GN=NAP1L1 PE=1 SV=1 4.14 3740.9 - 4.30E+06 - - - -0.2895 - 2.856 0.505 - 537.2 1 2 0 -0.0005 17 0 0 0 7.98E+07 6.41E+07 - - - 5.3508 1 221125_WJC_METTL3_EV_vs_WT_F02.22718.22718.2 3.27E-05 20-Dec R.AWDDFFPGSDR[166.11].F "sp|O75915|PRAF3_HUMAN,tr|F8WF33|F8WF33_HUMAN,tr|F8WF90|F8WF90_HUMAN,tr|C9JQU6|C9JQU6_HUMAN" 4 1321.5603 0.92 21527 22718 2 1321.560094 661.7874 PRA1 family protein 3 OS=Homo sapiens OX=9606 GN=ARL6IP5 PE=1 SV=1 3.93 3741.1 - 3.60E+06 - - - -0.1453 - 2.367 0.608 - 624.9 1 2 0 -0.0002 11 0 0 0 2.35E+07 2.56E+07 - - - 5.8625 1 221125_WJC_METTL3_EV_vs_WT_F02.22721.22721.2 1.09E-10 20/28 R.SETITEEELVGLMNK[136.11].F sp|P16152|CBR1_HUMAN 1 1699.843 1.23 21529 22721 2 1699.845629 850.9288 Carbonyl reductase [NADPH] 1 OS=Homo sapiens OX=9606 GN=CBR1 PE=1 SV=3 4.09 3741.4 - 4.02E+06 - - - 1.5654 - 3.522 0.692 - 1519.1 1 2 0 0.0027 15 0 0 0 2.31E+07 1.88E+07 - - - 7.2467 0.9641 221125_WJC_METTL3_EV_vs_WT_F02.22722.22722.2 0.000266 30-Dec K.EVEGDDVPESIMLEMK.A "sp|Q1KMD3|HNRL2_HUMAN,tr|H3BQZ7|H3BQZ7_HUMAN" 2 1819.822 2 21530 22722 2 1819.839471 910.9183 Heterogeneous nuclear ribonucleoprotein U-like protein 2 OS=Homo sapiens OX=9606 GN=HNRNPUL2 PE=1 SV=1 3.77 3741.5 - 1.84E+06 - - - 9.618 - 1.643 0.455 - 195.8 1 2 0 0.0175 16 0 0 0 7.19E+06 3.59E+06 - - - 3.6169 1 221125_WJC_METTL3_EV_vs_WT_F02.22723.22723.2 4.08E-14 21/36 R.YEGILYTIDTENSTVALAK[136.11].V "sp|Q8ND56|LS14A_HUMAN,tr|I3L4Q1|I3L4Q1_HUMAN,tr|A0A140TA76|A0A140TA76_HUMAN,tr|K7EMZ9|K7EMZ9_HUMAN" 4 2108.0769 1.2 21531 22723 2 2108.071267 1055.0457 Protein LSM14 homolog A OS=Homo sapiens OX=9606 GN=LSM14A PE=1 SV=3 4.14 3741.5 - 8.07E+07 - - - -2.6564 - 3.914 0.696 - 1250.9 1 2 0 -0.0056 19 0 0 0 1.57E+09 1.31E+09 - - - 7.5347 1 221125_WJC_METTL3_EV_vs_WT_F02.22725.22725.2 2.54E-15 23/40 K.DLYANTVLSGGTTMYPGIADR[166.11].M "sp|P63261|ACTG_HUMAN,sp|P60709|ACTB_HUMAN,tr|A0A804GS07|A0A804GS07_HUMAN,tr|E7EVS6|E7EVS6_HUMAN,tr|A0A6Q8PFE4|A0A6Q8PFE4_HUMAN,tr|A0A2R8Y793|A0A2R8Y793_HUMAN,tr|I3L4N8|I3L4N8_HUMAN" 7 2224.071 1.07 21533 22725 2 2224.066978 1113.0428 "Actin, cytoplasmic 2 OS=Homo sapiens OX=9606 GN=ACTG1 PE=1 SV=1" 4.21 3741.6 - 9.33E+06 - - - -1.7877 - 4.417 0.717 - 1400.5 1 2 0 -0.004 21 0 0 0 9.66E+07 9.00E+07 - - - 7.9876 1 221125_WJC_METTL3_EV_vs_WT_F02.22726.22726.2 1.16E-12 22/40 K.DLYANTVLSGGTTMYPGIADR.M "sp|P63261|ACTG_HUMAN,sp|P60709|ACTB_HUMAN,tr|A0A804GS07|A0A804GS07_HUMAN,tr|E7EVS6|E7EVS6_HUMAN,tr|A0A6Q8PFE4|A0A6Q8PFE4_HUMAN,tr|A0A2R8Y793|A0A2R8Y793_HUMAN,tr|I3L4N8|I3L4N8_HUMAN" 7 2214.0627 1.07 21534 22726 2 2214.059693 1108.0386 "Actin, cytoplasmic 2 OS=Homo sapiens OX=9606 GN=ACTG1 PE=1 SV=1" 4.21 3741.7 - 8.34E+06 - - - -1.3509 - 4.429 0.697 - 1239.9 1 2 0 -0.003 21 0 0 0 9.66E+07 9.00E+07 - - - 7.8468 0.977 221125_WJC_METTL3_EV_vs_WT_F02.22727.22727.2 5.71E-05 14/24 L.SLGIETLGGVFTK[136.11].L "sp|P38646|GRP75_HUMAN,tr|A0A7I2V2S7|A0A7I2V2S7_HUMAN,tr|A0A7I2V2G2|A0A7I2V2G2_HUMAN,tr|A0A7I2YQB2|A0A7I2YQB2_HUMAN,tr|D6RCD7|D6RCD7_HUMAN" 5 1328.7431 0.46 21535 22727 2 1328.739196 665.3788 "Stress-70 protein, mitochondrial OS=Homo sapiens OX=9606 GN=HSPA9 PE=1 SV=2" 5.72 3741.7 - 5.35E+06 - - - -2.9509 - 2.667 0.526 - 608.7 1 1 0 -0.0039 13 0 0 0 4.35E+07 9.37E+07 - - - 5.4425 0.9996 221125_WJC_METTL3_EV_vs_WT_F02.22729.22729.2 0.00107 22-Dec R.LAEISDVWEEMK[136.11].T "sp|Q01082|SPTB2_HUMAN,tr|A0A087WUZ3|A0A087WUZ3_HUMAN" 2 1456.6999 2.22 21537 22729 2 1456.697081 729.3572 "Spectrin beta chain, non-erythrocytic 1 OS=Homo sapiens OX=9606 GN=SPTBN1 PE=1 SV=2" 4 3741.9 - 3.21E+06 - - - -1.9572 - 2.347 0.392 - 482 1 2 0 -0.0029 12 0 0 0 2.47E+07 1.11E+07 - - - 4.1802 0.9965 221125_WJC_METTL3_EV_vs_WT_F02.22730.22730.2 1.22E-06 13/30 R.LLGQPSLDSLPIPAPR.G sp|Q9NUL7|DDX28_HUMAN 1 1672.9512 1.13 21538 22730 2 1672.942105 837.4829 Probable ATP-dependent RNA helicase DDX28 OS=Homo sapiens OX=9606 GN=DDX28 PE=1 SV=2 5.84 3741.9 - 2.88E+06 - - - -5.4401 - 2.488 0.458 - 372.7 1 2 0 -0.0091 16 0 0 0 3.60E+07 3.19E+07 - - - 4.6618 1 221125_WJC_METTL3_EV_vs_WT_F02.22731.22731.2 4.10E-06 17/30 R.LLGQPSLDSLPIPAPR[166.11].G sp|Q9NUL7|DDX28_HUMAN 1 1682.9595 1.13 21539 22731 2 1682.956217 842.487 Probable ATP-dependent RNA helicase DDX28 OS=Homo sapiens OX=9606 GN=DDX28 PE=1 SV=2 5.84 3742.1 - 2.86E+06 - - - -1.9365 - 2.894 0.557 - 783.7 1 2 0 -0.0033 16 0 0 0 3.60E+07 3.19E+07 - - - 5.7665 0.9996 221125_WJC_METTL3_EV_vs_WT_F02.22737.22737.2 5.66E-06 15/24 R.TIVQLENEIYQIK[136.11].Q sp|O75934|SPF27_HUMAN 1 1597.8807 1.43 21545 22737 2 1597.876533 799.9476 Pre-mRNA-splicing factor SPF27 OS=Homo sapiens OX=9606 GN=BCAS2 PE=1 SV=1 4.53 3742.8 - 978234 - - - -2.5916 - 2.846 0.432 - 574.9 1 2 0 -0.0041 13 0 0 0 1.43E+08 1.00E+08 - - - 4.9148 1 221125_WJC_METTL3_EV_vs_WT_F02.22741.22741.3 4.41E-09 15/64 R.LDGLVETPTGYIESLPR.V "sp|P55209|NP1L1_HUMAN,tr|F8VUX1|F8VUX1_HUMAN,tr|F8W118|F8W118_HUMAN,tr|F8VRJ2|F8VRJ2_HUMAN,tr|F8W0J6|F8W0J6_HUMAN,tr|F8VV59|F8VV59_HUMAN,tr|B7Z9C2|B7Z9C2_HUMAN,tr|F8VXI6|F8VXI6_HUMAN,tr|H0YHC3|H0YHC3_HUMAN,tr|H0YIV4|H0YIV4_HUMAN,tr|F5H4R6|F5H4R6_HUMAN,tr|F8W020|F8W020_HUMAN,tr|F8VY35|F8VY35_HUMAN" 13 1858.9676 1.27 21547 22741 3 1858.963635 620.6632 Nucleosome assembly protein 1-like 1 OS=Homo sapiens OX=9606 GN=NAP1L1 PE=1 SV=1 4.14 3743.3 - 5.64E+06 - - - -2.1566 - 2.718 0.547 - 289.5 1 2 0 -0.004 17 0 0 0 3.76E+07 2.96E+07 - - - 7.1634 0.9997 221125_WJC_METTL3_EV_vs_WT_F02.22742.22742.2 0.000155 16/24 R.TIVQLENEIYQIK.Q sp|O75934|SPF27_HUMAN 1 1589.8665 1.43 21548 22742 2 1589.862342 795.9405 Pre-mRNA-splicing factor SPF27 OS=Homo sapiens OX=9606 GN=BCAS2 PE=1 SV=1 4.53 3743.4 - 6.84E+06 - - - -2.599 - 3.103 0.5 - 749.7 1 2 0 -0.0041 13 0 0 0 1.43E+08 1.00E+08 - - - 5.639 0.9814 221125_WJC_METTL3_EV_vs_WT_F02.22745.22745.2 0.000498 14/24 L.SLGIETLGGVFTK.L "sp|P38646|GRP75_HUMAN,tr|A0A7I2V2S7|A0A7I2V2S7_HUMAN,tr|A0A7I2V2G2|A0A7I2V2G2_HUMAN,tr|A0A7I2YQB2|A0A7I2YQB2_HUMAN,tr|D6RCD7|D6RCD7_HUMAN" 5 1320.7289 0.47 21551 22745 2 1320.725758 661.3717 "Stress-70 protein, mitochondrial OS=Homo sapiens OX=9606 GN=HSPA9 PE=1 SV=2" 5.72 3743.6 - 4.07E+06 - - - -2.3919 - 2.601 0.479 - 595.4 1 1 0 -0.0032 13 0 0 0 4.40E+07 9.40E+07 - - - 5.0312 0.9985 221125_WJC_METTL3_EV_vs_WT_F02.22748.22748.2 6.81E-05 14/22 K.DLPFETLEVEAK.V "sp|Q9NYK5|RM39_HUMAN,tr|C9JG87|C9JG87_HUMAN" 2 1389.7028 23.3 21554 22748 2 1389.696831 695.8587 "39S ribosomal protein L39, mitochondrial OS=Homo sapiens OX=9606 GN=MRPL39 PE=1 SV=3" 4 3744 - 2.68E+06 - - - -4.2678 - 2.514 0.433 - 632.1 1 2 0 -0.0059 12 0 0 0 2.51E+07 1.08E+06 - - - 4.6629 1 221125_WJC_METTL3_EV_vs_WT_F02.22751.22751.2 1.26E-16 23/36 K.VIEDVAFAC[160.03]ALTSSVPTTK.K "sp|Q14527|HLTF_HUMAN,tr|A0A0C4DGA6|A0A0C4DGA6_HUMAN" 2 2008.0187 1.98 21557 22751 2 2008.014621 1005.0166 Helicase-like transcription factor OS=Homo sapiens OX=9606 GN=HLTF PE=1 SV=2 4.37 3744.4 - 2.28E+06 - - - -2.0284 - 4.672 0.742 - 1195.5 1 2 0 -0.0041 19 0 0 0 1.66E+07 8.37E+06 - - - 8.3102 1 221125_WJC_METTL3_EV_vs_WT_F02.22752.22752.2 1.97E-11 15/28 K.LVVVDFSATWC[160.03]GPC[160.03]K[136.11].M sp|P10599|THIO_HUMAN 1 1745.836 0.02 21558 22752 2 1745.832248 873.9253 Thioredoxin OS=Homo sapiens OX=9606 GN=TXN PE=1 SV=3 5.82 3744.6 - 2.00E+06 - - - -2.1772 - 2.943 0.738 - 630.2 1 2 0 -0.0038 15 0 0 0 3.62E+05 2.15E+07 - - - 7.1445 0.9992 221125_WJC_METTL3_EV_vs_WT_F02.22757.22757.2 3.68E-07 15/36 K.FSPGFFPGTGDVSDVGLGK[136.11].G "sp|Q9BY41|HDAC8_HUMAN,tr|A0A3B3IT04|A0A3B3IT04_HUMAN,tr|A0A3B3ISS7|A0A3B3ISS7_HUMAN,tr|A0A3B3IS68|A0A3B3IS68_HUMAN,tr|A0A3B3IT84|A0A3B3IT84_HUMAN,tr|A0A3B3IRI9|A0A3B3IRI9_HUMAN,tr|A0A3B3IRV1|A0A3B3IRV1_HUMAN,tr|A0A3B3IU62|A0A3B3IU62_HUMAN,tr|A0A3B3IT30|A0A3B3IT30_HUMAN,tr|A0A3B3IRP8|A0A3B3IRP8_HUMAN,tr|A0A3B3ISE4|A0A3B3ISE4_HUMAN,tr|A0A3B3IRZ0|A0A3B3IRZ0_HUMAN,tr|A0A3B3ITZ3|A0A3B3ITZ3_HUMAN,tr|A6NMT1|A6NMT1_HUMAN,tr|E7EVA8|E7EVA8_HUMAN,tr|A0A3B3IRZ8|A0A3B3IRZ8_HUMAN,tr|A0A3B3IT95|A0A3B3IT95_HUMAN,tr|A0A3B3ISJ4|A0A3B3ISJ4_HUMAN,tr|A6NGJ7|A6NGJ7_HUMAN" 19 1890.9243 0.59 21563 22757 2 1890.91737 946.4694 Histone deacetylase 8 OS=Homo sapiens OX=9606 GN=HDAC8 PE=1 SV=2 4.21 3745.2 - 943236 - - - -3.6802 - 2.259 0.55 - 337.8 1 2 0 -0.007 19 0 0 0 4.96E+06 8.41E+06 - - - 5.1046 0.9052 221125_WJC_METTL3_EV_vs_WT_F02.22761.22761.2 0.436 20-Aug K.K[136.11]VSQEILELLN.T "sp|Q86U44|MTA70_HUMAN,tr|H0YFV6|H0YFV6_HUMAN" 2 1292.7431 0.01 21565 22761 2 1292.741599 647.3788 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 4.53 3745.6 - 4.40E+06 - - - -1.1742 - 1.821 0.197 - 202.2 1 1 0 -0.0015 11 0 0 0 1.39E+06 1.74E+08 - - - 2.117 0.9998 221125_WJC_METTL3_EV_vs_WT_F02.22763.22763.2 0.000371 18-Oct R.EADDIVNWLK.K "sp|P07237|PDIA1_HUMAN,tr|A0A7P0TA97|A0A7P0TA97_HUMAN,tr|A0A7P0TA71|A0A7P0TA71_HUMAN,tr|I3L4M2|I3L4M2_HUMAN,tr|A0A7P0T9D6|A0A7P0T9D6_HUMAN,tr|A0A7P0T9K9|A0A7P0T9K9_HUMAN,tr|A0A7P0Z4S2|A0A7P0Z4S2_HUMAN,tr|A0A7P0TA35|A0A7P0TA35_HUMAN,tr|A0A7P0TAX9|A0A7P0TAX9_HUMAN,tr|I3L514|I3L514_HUMAN,tr|A0A7P0TB26|A0A7P0TB26_HUMAN,tr|A0A7P0T9U6|A0A7P0T9U6_HUMAN,tr|I3L0S0|I3L0S0_HUMAN,tr|I3L3P5|I3L3P5_HUMAN,tr|A0A7P0T8J3|A0A7P0T8J3_HUMAN,tr|A0A7P0Z4J0|A0A7P0Z4J0_HUMAN,tr|A0A7P0T8X1|A0A7P0T8X1_HUMAN" 17 1201.5979 1.51 21567 22763 2 1201.597231 601.8062 Protein disulfide-isomerase OS=Homo sapiens OX=9606 GN=P4HB PE=1 SV=3 4.03 3745.7 - 5.69E+06 - - - -0.5593 - 2.095 0.408 - 278.5 1 2 0 -0.0007 10 0 0 0 1.63E+08 1.08E+08 - - - 4.1186 1 221125_WJC_METTL3_EV_vs_WT_F02.22769.22769.3 5.21E-09 19/72 R.GAQAAIVVYDITNQETFAR.A "sp|P61020|RAB5B_HUMAN,tr|F8VUA5|F8VUA5_HUMAN" 2 2066.0433 1.69 21573 22769 3 2066.045596 689.6884 Ras-related protein Rab-5B OS=Homo sapiens OX=9606 GN=RAB5B PE=1 SV=1 4.37 3746.4 - 1.63E+06 - - - 1.1263 - 3.994 0.584 - 562.6 1 2 0 0.0023 19 0 0 0 1.80E+07 1.07E+07 - - - 8.4525 0.9369 221125_WJC_METTL3_EV_vs_WT_F02.22770.22770.2 7.09E-05 26-Nov K.K[136.11]IGYNPDTVAFVPI.S "sp|P68104|EF1A1_HUMAN,sp|Q5VTE0|EF1A3_HUMAN,tr|A0A7I2V659|A0A7I2V659_HUMAN,tr|A0A7I2V3H3|A0A7I2V3H3_HUMAN,tr|A0A7I2V5N4|A0A7I2V5N4_HUMAN,tr|A0A087WVQ9|A0A087WVQ9_HUMAN,tr|A0A087WV01|A0A087WV01_HUMAN" 7 1540.8381 0.66 21574 22770 2 1540.843668 771.4263 Elongation factor 1-alpha 1 OS=Homo sapiens OX=9606 GN=EEF1A1 PE=1 SV=1 5.83 3746.5 - 647458 - - - 3.6259 - 2.065 0.486 - 183.3 1 1 0 0.0056 14 0 0 0 9.01E+06 1.37E+07 - - - 4.4485 0.9999 221125_WJC_METTL3_EV_vs_WT_F02.22775.22775.2 9.89E-05 18-Nov R.EADDIVNWLK[136.11].K "sp|P07237|PDIA1_HUMAN,tr|A0A7P0TA97|A0A7P0TA97_HUMAN,tr|A0A7P0TA71|A0A7P0TA71_HUMAN,tr|I3L4M2|I3L4M2_HUMAN,tr|A0A7P0T9D6|A0A7P0T9D6_HUMAN,tr|A0A7P0T9K9|A0A7P0T9K9_HUMAN,tr|A0A7P0Z4S2|A0A7P0Z4S2_HUMAN,tr|A0A7P0TA35|A0A7P0TA35_HUMAN,tr|A0A7P0TAX9|A0A7P0TAX9_HUMAN,tr|I3L514|I3L514_HUMAN,tr|A0A7P0TB26|A0A7P0TB26_HUMAN,tr|A0A7P0T9U6|A0A7P0T9U6_HUMAN,tr|I3L0S0|I3L0S0_HUMAN,tr|I3L3P5|I3L3P5_HUMAN,tr|A0A7P0T8J3|A0A7P0T8J3_HUMAN,tr|A0A7P0Z4J0|A0A7P0Z4J0_HUMAN,tr|A0A7P0T8X1|A0A7P0T8X1_HUMAN" 17 1209.6121 1.51 21577 22775 2 1209.611186 605.8133 Protein disulfide-isomerase OS=Homo sapiens OX=9606 GN=P4HB PE=1 SV=3 4.03 3747 - 7.51E+06 - - - -0.7581 - 2.321 0.516 - 455.8 1 2 0 -0.0009 10 0 0 0 1.63E+08 1.08E+08 - - - 5.2022 0.9999 221125_WJC_METTL3_EV_vs_WT_F02.22776.22776.3 1.93E-05 13/48 R.TIVQLENEIYQIK.Q sp|O75934|SPF27_HUMAN 1 1589.8665 1.42 21578 22776 3 1589.866335 530.9628 Pre-mRNA-splicing factor SPF27 OS=Homo sapiens OX=9606 GN=BCAS2 PE=1 SV=1 4.53 3747 - 4.15E+06 - - - -0.0874 - 2.586 0.415 - 230.9 1 2 0 -0.0001 13 0 0 0 4.14E+07 2.92E+07 - - - 5.7428 0.9998 221125_WJC_METTL3_EV_vs_WT_F02.22778.22778.2 8.41E-06 14/26 R.ELLEQISAFDNVPR[166.11].K sp|Q9NX58|LYAR_HUMAN 1 1639.8445 0.57 21580 22778 2 1639.847161 820.9295 Cell growth-regulating nucleolar protein OS=Homo sapiens OX=9606 GN=LYAR PE=1 SV=2 4.14 3747.1 - 3.25E+06 - - - 1.6191 - 2.942 0.467 - 715.6 1 2 0 0.0027 14 0 0 0 2.34E+07 4.12E+07 - - - 5.1973 1 221125_WJC_METTL3_EV_vs_WT_F02.22780.22780.2 5.94E-09 17/32 R.IPSTPDSFMDPASALYR.G sp|P28070|PSB4_HUMAN 1 1866.8822 4.59 21582 22780 2 1866.88026 934.4484 Proteasome subunit beta type-4 OS=Homo sapiens OX=9606 GN=PSMB4 PE=1 SV=4 4.21 3747.3 - 2.54E+06 - - - -1.0392 - 2.911 0.61 - 528.6 1 2 0 -0.0019 17 0 0 0 5.27E+07 1.15E+07 - - - 6.1728 1 221125_WJC_METTL3_EV_vs_WT_F02.22782.22782.2 2.87E-09 15/30 K.TLPDDQTEVVIYVVER[166.11].S sp|Q7Z3B4|NUP54_HUMAN 1 1884.9708 3.43 21584 22782 2 1884.976263 943.4927 Nucleoporin p54 OS=Homo sapiens OX=9606 GN=NUP54 PE=1 SV=2 3.92 3747.5 - 1.52E+06 - - - 2.8828 - 3.149 0.682 - 988.5 1 2 0 0.0054 16 0 0 0 4.39E+07 1.28E+07 - - - 6.8967 0.9999 221125_WJC_METTL3_EV_vs_WT_F02.22787.22787.2 6.20E-05 14/22 R.TVQDALESLVAR.E "sp|Q14694|UBP10_HUMAN,tr|H3BQP1|H3BQP1_HUMAN,tr|H3BNS8|H3BNS8_HUMAN" 3 1300.6987 0.88 21587 22787 2 1300.697452 651.3566 Ubiquitin carboxyl-terminal hydrolase 10 OS=Homo sapiens OX=9606 GN=USP10 PE=1 SV=2 4.37 3748.1 - 3.02E+06 - - - -0.9441 - 2.465 0.489 - 661.7 1 2 0 -0.0012 12 0 0 0 3.19E+07 3.62E+07 - - - 5.0262 0.9995 221125_WJC_METTL3_EV_vs_WT_F02.22788.22788.2 5.28E-05 14/28 R.EQLLALSAC[160.03]APFNVR[166.11].F sp|Q8IU81|I2BP1_HUMAN 1 1697.8798 0.82 21588 22788 2 1697.875318 849.9472 Interferon regulatory factor 2-binding protein 1 OS=Homo sapiens OX=9606 GN=IRF2BP1 PE=1 SV=1 6.09 3748.2 - 2.02E+06 - - - -2.6669 - 2.828 0.414 - 700.8 1 2 0 -0.0045 15 0 0 0 1.81E+07 2.21E+07 - - - 4.6532 1 221125_WJC_METTL3_EV_vs_WT_F02.22790.22790.3 0.00258 16/64 K.VPEFQFLIGDEAATHLK.Q "sp|P34949|MPI_HUMAN,tr|H3BPB8|H3BPB8_HUMAN,tr|H3BP57|H3BP57_HUMAN,tr|H3BT48|H3BT48_HUMAN,tr|H3BU66|H3BU66_HUMAN,tr|H3BQX0|H3BQX0_HUMAN,tr|H3BUZ9|H3BUZ9_HUMAN,tr|H3BPM5|H3BPM5_HUMAN,tr|H3BPP3|H3BPP3_HUMAN,tr|F5GX71|F5GX71_HUMAN,tr|H3BMZ9|H3BMZ9_HUMAN,tr|H3BNY8|H3BNY8_HUMAN" 12 1913.9887 1.75 21590 22790 3 1913.990427 639.0035 Mannose-6-phosphate isomerase OS=Homo sapiens OX=9606 GN=MPI PE=1 SV=2 4.65 3748.4 - 1.72E+06 - - - 0.895 - 3.023 0.487 - 386.9 1 2 0 0.0017 17 0 0 0 2.60E+07 1.49E+07 - - - 6.7638 0.9998 221125_WJC_METTL3_EV_vs_WT_F02.22791.22791.3 0.126 15/64 K.ILQSLSAAQELDPLTVR.D sp|O95396|MOCS3_HUMAN 1 1853.0258 2.39 21591 22791 3 1853.024174 618.6826 Adenylyltransferase and sulfurtransferase MOCS3 OS=Homo sapiens OX=9606 GN=MOCS3 PE=1 SV=1 4.37 3748.5 - 1.33E+06 - - - -0.8926 - 2.845 0.3 - 215.1 1 2 0 -0.0017 17 0 0 0 1.23E+07 5.15E+06 - - - 4.5257 1 221125_WJC_METTL3_EV_vs_WT_F02.22792.22792.3 1.76E-08 20/80 K.LAQQYYLVYQEPIPTAQLVQR.V "sp|P25787|PSA2_HUMAN,tr|A0A024RA52|A0A024RA52_HUMAN,tr|A0A7I2V2H3|A0A7I2V2H3_HUMAN,tr|C9JCK5|C9JCK5_HUMAN,tr|A0A7I2YQP7|A0A7I2YQP7_HUMAN" 5 2520.3377 1.69 21592 22792 3 2520.333068 841.1198 Proteasome subunit alpha type-2 OS=Homo sapiens OX=9606 GN=PSMA2 PE=1 SV=2 6 3748.7 - 1.30E+06 - - - -1.822 - 3.077 0.6 - 376.2 1 2 0 -0.0046 21 0 0 0 1.40E+07 8.27E+06 - - - 7.9228 1 221125_WJC_METTL3_EV_vs_WT_F02.22793.22793.2 1.04E-10 15/28 K.TFDTFC[160.03]PLGPALVTK.D "sp|Q6P2I3|FAH2B_HUMAN,sp|Q96GK7|FAH2A_HUMAN" 2 1665.8436 0.94 21593 22793 2 1665.844896 833.9291 Fumarylacetoacetate hydrolase domain-containing protein 2B OS=Homo sapiens OX=9606 GN=FAHD2B PE=1 SV=1 5.5 3748.8 - 1.20E+06 - - - 0.76 - 2.832 0.616 - 700.7 1 2 0 0.0013 15 0 0 0 2.62E+07 2.79E+07 - - - 6.1497 0.9997 221125_WJC_METTL3_EV_vs_WT_F02.22796.22796.3 0.000905 14/56 R.EQLLALSAC[160.03]APFNVR[166.11].F sp|Q8IU81|I2BP1_HUMAN 1 1697.8798 1.18 21596 22796 3 1697.87852 566.9672 Interferon regulatory factor 2-binding protein 1 OS=Homo sapiens OX=9606 GN=IRF2BP1 PE=1 SV=1 6.09 3749.2 - 1.07E+06 - - - -0.781 - 2.228 0.313 - 243.2 1 2 0 -0.0013 15 0 0 0 7.78E+06 6.61E+06 - - - 4.1196 1 221125_WJC_METTL3_EV_vs_WT_F02.22798.22798.3 0.000158 14/44 K.RLNIFDMMAVTK.E sp|Q92665|RT31_HUMAN 1 1437.7472 2.33 21598 22798 3 1437.746439 480.2564 "28S ribosomal protein S31, mitochondrial OS=Homo sapiens OX=9606 GN=MRPS31 PE=1 SV=3" 8.75 3749.5 - 1.04E+06 - - - -0.5481 - 2.575 0.551 - 234.5 1 2 0 -0.0008 12 0 0 0 1.52E+07 6.54E+06 - - - 7.3046 1 221125_WJC_METTL3_EV_vs_WT_F02.22799.22799.2 2.08E-09 15/34 K.LDDGSIGVVTPYADQVFR.L "sp|P42694|HELZ_HUMAN,tr|J3QS41|J3QS41_HUMAN" 2 1950.9687 2.53 21599 22799 2 1950.972216 976.4916 Probable helicase with zinc finger domain OS=Homo sapiens OX=9606 GN=HELZ PE=1 SV=2 3.93 3749.6 - 1.03E+06 - - - 1.7986 - 3.266 0.643 - 536.9 1 2 0 0.0035 18 0 0 0 2.76E+07 1.09E+07 - - - 6.6989 1 221125_WJC_METTL3_EV_vs_WT_F02.22803.22803.3 1.29E-06 15/52 R.ELLEQISAFDNVPR[166.11].K sp|Q9NX58|LYAR_HUMAN 1 1639.8445 0.52 21602 22803 3 1639.846266 547.6221 Cell growth-regulating nucleolar protein OS=Homo sapiens OX=9606 GN=LYAR PE=1 SV=2 4.14 3750.1 - 1.04E+06 - - - 1.0733 - 2.721 0.525 - 296.2 1 2 0 0.0018 14 0 0 0 1.02E+07 1.95E+07 - - - 7.0529 0.9671 221125_WJC_METTL3_EV_vs_WT_F02.22805.22805.2 0.00745 22-Nov R.VLQGLEIELQSQ.L "sp|P08779|K1C16_HUMAN,tr|K7ENW6|K7ENW6_HUMAN" 2 1355.7296 - 21603 22805 2 1355.727253 678.8721 "Keratin, type I cytoskeletal 16 OS=Homo sapiens OX=9606 GN=KRT16 PE=1 SV=4" 3.79 3750.3 - 6.19E+06 - - - -1.7651 - 2.151 0.337 - 391.3 1 1 0 -0.0024 12 0 0 0 - - - - - 3.5446 1 221125_WJC_METTL3_EV_vs_WT_F02.22806.22806.3 3.37E-07 Oct-60 K.TLPDDQTEVVIYVVER.S sp|Q7Z3B4|NUP54_HUMAN 1 1874.9626 1.19 21604 22806 3 1874.964405 625.9948 Nucleoporin p54 OS=Homo sapiens OX=9606 GN=NUP54 PE=1 SV=2 3.92 3750.4 - 3.97E+06 - - - 0.9846 - 2.187 0.602 - 107.6 1 2 0 0.0018 16 0 0 0 6.70E+07 5.62E+07 - - - 7.2591 0.9999 221125_WJC_METTL3_EV_vs_WT_F02.22808.22808.3 3.13E-07 14/44 R.YGREEMLALFLK.D "sp|Q6Y7W6|GGYF2_HUMAN,tr|F8WCD5|F8WCD5_HUMAN,tr|C9JPV7|C9JPV7_HUMAN,tr|C9JRZ2|C9JRZ2_HUMAN,tr|C9J0V6|C9J0V6_HUMAN,tr|I1E4Y6|I1E4Y6_HUMAN,tr|C9JHT0|C9JHT0_HUMAN,tr|C9JXQ0|C9JXQ0_HUMAN,tr|C9JHW1|C9JHW1_HUMAN,tr|E7ESB6|E7ESB6_HUMAN" 10 1468.7748 2.34 21606 22808 3 1468.775039 490.5989 GRB10-interacting GYF protein 2 OS=Homo sapiens OX=9606 GN=GIGYF2 PE=1 SV=1 6.14 3750.5 - 3.74E+06 - - - 0.1477 - 2.479 0.492 - 363 1 2 1 0.0002 12 0 0 0 4.93E+07 2.10E+07 - - - 6.5417 1 221125_WJC_METTL3_EV_vs_WT_F02.22810.22810.2 3.25E-08 15/26 R.ELDSITPEVLPGWK.G "sp|Q16891|MIC60_HUMAN,tr|B9A067|B9A067_HUMAN,tr|C9J406|C9J406_HUMAN,tr|H7C463|H7C463_HUMAN" 4 1582.8243 1.52 21608 22810 2 1582.825952 792.4194 MICOS complex subunit MIC60 OS=Homo sapiens OX=9606 GN=IMMT PE=1 SV=1 4.14 3750.6 - 3.31E+06 - - - 1.0601 - 2.688 0.615 - 536 1 2 0 0.0017 14 0 0 0 3.33E+08 2.18E+08 - - - 6.0642 1 221125_WJC_METTL3_EV_vs_WT_F02.22813.22813.2 6.90E-07 17/30 R.VWDISTVSSVNEAFGR.R "sp|Q13610|PWP1_HUMAN,tr|B4DJV5|B4DJV5_HUMAN" 2 1765.8635 2.32 21611 22813 2 1765.866201 883.939 Periodic tryptophan protein 1 homolog OS=Homo sapiens OX=9606 GN=PWP1 PE=1 SV=1 4.37 3750.8 - 2.13E+06 - - - 1.5216 - 3.523 0.619 - 851.7 1 2 0 0.0027 16 0 0 0 1.95E+07 8.40E+06 - - - 6.7082 0.9998 221125_WJC_METTL3_EV_vs_WT_F02.22815.22815.3 0.00345 15/68 K.AIGAVPLIQGEYMIPC[160.03]EK.V "sp|P07339|CATD_HUMAN,tr|A0A1B0GW44|A0A1B0GW44_HUMAN,tr|A0A1B0GVD5|A0A1B0GVD5_HUMAN,tr|A0A1B0GV23|A0A1B0GV23_HUMAN,tr|C9JH19|C9JH19_HUMAN,tr|H7C469|H7C469_HUMAN,tr|A0A1B0GWE8|A0A1B0GWE8_HUMAN,tr|A0A1B0GU03|A0A1B0GU03_HUMAN,tr|A0A1B0GU92|A0A1B0GU92_HUMAN,tr|F8W787|F8W787_HUMAN" 10 1988.0111 5.14 21613 22815 3 1988.010314 663.6776 Cathepsin D OS=Homo sapiens OX=9606 GN=CTSD PE=1 SV=1 4.53 3751 - 1.29E+06 - - - -0.3984 - 2.433 0.326 - 191.8 1 2 0 -0.0008 18 0 0 0 1.79E+07 3.48E+06 - - - 4.3884 0.9998 221125_WJC_METTL3_EV_vs_WT_F02.22816.22816.3 3.93E-05 14/44 R.WK[136.11]LGDDIDLIVR[166.11].C sp|O15371|EIF3D_HUMAN 1 1459.8154 0.92 21614 22816 3 1459.815034 487.6124 Eukaryotic translation initiation factor 3 subunit D OS=Homo sapiens OX=9606 GN=EIF3D PE=1 SV=1 4.43 3751.1 - 1.19E+06 - - - -0.2404 - 2.535 0.467 - 335.4 1 2 1 -0.0004 12 0 0 0 1.39E+07 1.51E+07 - - - 6.3248 0.9994 221125_WJC_METTL3_EV_vs_WT_F02.22818.22818.2 2.55E-05 13/30 R.VWDISTVSSVNEAFGR[166.11].R "sp|Q13610|PWP1_HUMAN,tr|B4DJV5|B4DJV5_HUMAN" 2 1775.8718 2.32 21616 22818 2 1775.866215 888.9432 Periodic tryptophan protein 1 homolog OS=Homo sapiens OX=9606 GN=PWP1 PE=1 SV=1 4.37 3751.4 - 936862 - - - -3.1359 - 2.651 0.446 - 310.2 1 2 0 -0.0056 16 0 0 0 1.95E+07 8.40E+06 - - - 4.7303 1 221125_WJC_METTL3_EV_vs_WT_F02.22821.22821.3 6.70E-05 18/52 R.TEVWGLVLLSEEKR.L sp|Q9UNX4|WDR3_HUMAN 1 1657.9039 1.11 21619 22821 3 1657.903278 553.6419 WD repeat-containing protein 3 OS=Homo sapiens OX=9606 GN=WDR3 PE=1 SV=1 4.78 3751.7 - 658797 - - - -0.3884 - 2.963 0.526 - 511.2 1 2 0 -0.0006 14 0 0 0 9.55E+06 8.61E+06 - - - 7.2908 0.9994 221125_WJC_METTL3_EV_vs_WT_F02.22822.22822.2 3.33E-06 28-Dec K.TQEQLALEMAELTAR[166.11].L sp|P26038|MOES_HUMAN 1 1712.8643 2.83 21620 22822 2 1712.870286 857.4394 Moesin OS=Homo sapiens OX=9606 GN=MSN PE=1 SV=3 4.25 3751.9 - 566523 - - - 3.521 - 2.909 0.533 - 461.4 1 2 0 0.006 15 0 0 0 7.10E+06 2.51E+06 - - - 5.6011 0.9999 221125_WJC_METTL3_EV_vs_WT_F02.22823.22823.3 0.00166 Dec-48 R.LAAVALINAAIQK.G "sp|P46940|IQGA1_HUMAN,tr|A0A0J9YXZ5|A0A0J9YXZ5_HUMAN" 2 1294.7973 1.48 21621 22823 3 1294.795136 432.6064 Ras GTPase-activating-like protein IQGAP1 OS=Homo sapiens OX=9606 GN=IQGAP1 PE=1 SV=1 8.75 3752 - 551712 - - - -1.6497 - 2.682 0.396 - 197.9 1 2 0 -0.0021 13 0 0 0 2.96E+06 2.00E+06 - - - 5.6293 0.9619 221125_WJC_METTL3_EV_vs_WT_F02.22827.22827.2 0.0244 Aug-32 K.GSLGGGFSSGGFSGGSF.S "sp|P13645|K1C10_HUMAN,tr|A0A1B0GVI3|A0A1B0GVI3_HUMAN" 2 1463.6317 - 21623 22827 2 1463.632069 732.8231 "Keratin, type I cytoskeletal 10 OS=Homo sapiens OX=9606 GN=KRT10 PE=1 SV=6" 5.52 3752.5 - 6.59E+06 - - - 0.2364 - 1.395 0.395 - 104.3 1 1 0 0.0003 17 0 0 0 - - - - - 2.7768 1 221125_WJC_METTL3_EV_vs_WT_F02.22828.22828.2 7.94E-09 13/28 K.TFDTFC[160.03]PLGPALVTK[136.11].D "sp|Q6P2I3|FAH2B_HUMAN,sp|Q96GK7|FAH2A_HUMAN" 2 1673.8578 0.94 21624 22828 2 1673.860338 837.9362 Fumarylacetoacetate hydrolase domain-containing protein 2B OS=Homo sapiens OX=9606 GN=FAHD2B PE=1 SV=1 5.5 3752.6 - 1.84E+06 - - - 1.4983 - 2.524 0.636 - 451 1 2 0 0.0025 15 0 0 0 2.62E+07 2.79E+07 - - - 6.0139 1 221125_WJC_METTL3_EV_vs_WT_F02.22829.22829.3 1.23E-08 23/72 K.KLGGSLADSYLDEGFLLDK.K "sp|P78371|TCPB_HUMAN,tr|F8VQ14|F8VQ14_HUMAN,tr|F5GWF6|F5GWF6_HUMAN" 3 2040.0415 0.53 21625 22829 3 2040.046915 681.0211 T-complex protein 1 subunit beta OS=Homo sapiens OX=9606 GN=CCT2 PE=1 SV=4 4.23 3752.7 - 2.52E+06 - - - 2.6357 - 3.982 0.566 - 850.3 1 2 0 0.0054 19 0 0 0 1.70E+07 3.19E+07 - - - 8.2436 1 221125_WJC_METTL3_EV_vs_WT_F02.22830.22830.3 0.000122 14/56 R.DYLHLPPEIVPATLR[166.11].R "sp|P46783|RS10_HUMAN,tr|A0A2R8Y6L3|A0A2R8Y6L3_HUMAN,tr|F6U211|F6U211_HUMAN,tr|A0A1W2PQS6|A0A1W2PQS6_HUMAN,tr|A0A2R8YFH6|A0A2R8YFH6_HUMAN,tr|A0A2R8Y7H1|A0A2R8Y7H1_HUMAN,tr|S4R435|S4R435_HUMAN" 7 1742.9595 1.37 21626 22830 3 1742.961214 581.9938 40S ribosomal protein S10 OS=Homo sapiens OX=9606 GN=RPS10 PE=1 SV=1 5.32 3752.8 - 2.36E+06 - - - 0.9972 - 2.907 0.528 - 205.9 1 2 0 0.0017 15 0 0 0 3.10E+09 2.26E+09 - - - 7.2107 1 221125_WJC_METTL3_EV_vs_WT_F02.22831.22831.3 2.60E-07 14/56 R.DYLHLPPEIVPATLR.R "sp|P46783|RS10_HUMAN,tr|A0A2R8Y6L3|A0A2R8Y6L3_HUMAN,tr|F6U211|F6U211_HUMAN,tr|A0A1W2PQS6|A0A1W2PQS6_HUMAN,tr|A0A2R8YFH6|A0A2R8YFH6_HUMAN,tr|A0A2R8Y7H1|A0A2R8Y7H1_HUMAN,tr|S4R435|S4R435_HUMAN" 7 1732.9512 1.37 21627 22831 3 1732.949335 578.6577 40S ribosomal protein S10 OS=Homo sapiens OX=9606 GN=RPS10 PE=1 SV=1 5.32 3752.8 - 2.28E+06 - - - -1.0797 - 2.517 0.6 - 155.4 1 2 0 -0.0019 15 0 0 0 3.10E+09 2.26E+09 - - - 7.6375 0.9998 221125_WJC_METTL3_EV_vs_WT_F02.22833.22833.2 2.58E-05 13/34 K.SSASAPDVDDPEAFPALA.- sp|Q8NC51|PAIRB_HUMAN 1 1758.7948 - 21629 22833 2 1758.796823 880.4047 Plasminogen activator inhibitor 1 RNA-binding protein OS=Homo sapiens OX=9606 GN=SERBP1 PE=1 SV=2 3.37 3753.1 - 1.58E+06 - - - 1.136 - 1.84 0.545 - 215.9 1 2 0 0.002 18 0 0 0 - - - - - 4.5649 0.9999 221125_WJC_METTL3_EV_vs_WT_F02.22834.22834.3 3.05E-06 17/76 K.VVKPLDYEAMQSLQLSIGVR.N sp|Q02413|DSG1_HUMAN 1 2245.214 999 21630 22834 3 2245.21947 749.412 Desmoglein-1 OS=Homo sapiens OX=9606 GN=DSG1 PE=1 SV=2 6.04 3753.2 - 1.56E+06 - - - 2.4189 - 3.013 0.455 - 290.8 1 2 0 0.0054 20 0 0 0 1.44E+07 0.00E+00 - - - 6.287 0.9996 221125_WJC_METTL3_EV_vs_WT_F02.22835.22835.2 3.22E-06 22-Oct K.LNGFQLENFTLK.V sp|O00425|IF2B3_HUMAN 1 1422.7507 1.59 21631 22835 2 1422.754524 712.3826 Insulin-like growth factor 2 mRNA-binding protein 3 OS=Homo sapiens OX=9606 GN=IGF2BP3 PE=1 SV=2 6 3753.2 - 1.46E+06 - - - 2.6765 - 2.523 0.464 - 381.9 1 2 0 0.0038 12 0 0 0 3.54E+07 2.23E+07 - - - 4.9019 0.9999 221125_WJC_METTL3_EV_vs_WT_F02.22837.22837.2 8.01E-06 14/34 K.AIGAVPLIQGEYMIPC[160.03]EK.V "sp|P07339|CATD_HUMAN,tr|A0A1B0GW44|A0A1B0GW44_HUMAN,tr|A0A1B0GVD5|A0A1B0GVD5_HUMAN,tr|A0A1B0GV23|A0A1B0GV23_HUMAN,tr|C9JH19|C9JH19_HUMAN,tr|H7C469|H7C469_HUMAN,tr|A0A1B0GWE8|A0A1B0GWE8_HUMAN,tr|A0A1B0GU03|A0A1B0GU03_HUMAN,tr|A0A1B0GU92|A0A1B0GU92_HUMAN,tr|F8W787|F8W787_HUMAN" 10 1988.0111 5.32 21633 22837 2 1988.011697 995.0128 Cathepsin D OS=Homo sapiens OX=9606 GN=CTSD PE=1 SV=1 4.53 3753.5 - 1.37E+06 - - - 0.2973 - 2.519 0.482 - 359 1 2 0 0.0006 18 0 0 0 2.03E+07 3.81E+06 - - - 4.8722 0.9997 221125_WJC_METTL3_EV_vs_WT_F02.22838.22838.3 0.000747 14/52 R.ELDSITPEVLPGWK.G "sp|Q16891|MIC60_HUMAN,tr|B9A067|B9A067_HUMAN,tr|C9J406|C9J406_HUMAN,tr|H7C463|H7C463_HUMAN" 4 1582.8243 1.46 21634 22838 3 1582.828253 528.6154 MICOS complex subunit MIC60 OS=Homo sapiens OX=9606 GN=IMMT PE=1 SV=1 4.14 3753.6 - 1.33E+06 - - - 2.5139 - 2.472 0.365 - 215.2 1 2 0 0.004 14 0 0 0 2.71E+07 1.85E+07 - - - 5.0134 1 221125_WJC_METTL3_EV_vs_WT_F02.22839.22839.2 6.31E-06 14/22 K.AALEYLEDIDLK.T sp|Q9BRX8|PXL2A_HUMAN 1 1391.7184 1.24 21635 22839 2 1391.723394 696.8665 Peroxiredoxin-like 2A OS=Homo sapiens OX=9606 GN=PRXL2A PE=1 SV=3 3.92 3753.7 - 1.30E+06 - - - 3.5797 - 3.028 0.516 - 1071 1 2 0 0.005 12 0 0 0 1.18E+07 9.53E+06 - - - 5.7657 0.9998 221125_WJC_METTL3_EV_vs_WT_F02.22840.22840.3 0.000108 Dec-52 R.FAGLHFFNPVPVMK.L "sp|Q16836|HCDH_HUMAN,tr|A0A1W2PQC2|A0A1W2PQC2_HUMAN,tr|A0A804HJW7|A0A804HJW7_HUMAN,tr|A0A0D9SFP2|A0A0D9SFP2_HUMAN,tr|E9PF18|E9PF18_HUMAN,tr|A0A0A0MSE2|A0A0A0MSE2_HUMAN,tr|A0A804HKJ2|A0A804HKJ2_HUMAN,tr|A0A1W2PRT2|A0A1W2PRT2_HUMAN,tr|A0A1W2PQV5|A0A1W2PQV5_HUMAN,tr|A0A1W2PNM1|A0A1W2PNM1_HUMAN" 10 1602.8381 0.92 21636 22840 3 1602.839161 535.2866 "Hydroxyacyl-coenzyme A dehydrogenase, mitochondrial OS=Homo sapiens OX=9606 GN=HADH PE=1 SV=3" 8.76 3753.8 - 1.23E+06 - - - 0.6676 - 1.825 0.418 - 97.2 1 2 0 0.0011 14 0 0 0 8.08E+06 8.82E+06 - - - 4.7987 0.9999 221125_WJC_METTL3_EV_vs_WT_F02.22842.22842.2 0.000687 13/22 K.LNGFQLENFTLK[136.11].V sp|O00425|IF2B3_HUMAN 1 1430.7649 1.59 21638 22842 2 1430.764985 716.3897 Insulin-like growth factor 2 mRNA-binding protein 3 OS=Homo sapiens OX=9606 GN=IGF2BP3 PE=1 SV=2 6 3754.1 - 1.12E+06 - - - 0.0482 - 2.811 0.464 - 818.4 1 2 0 0.0001 12 0 0 0 3.54E+07 2.23E+07 - - - 5.1875 0.9999 221125_WJC_METTL3_EV_vs_WT_F02.22846.22846.2 2.16E-05 22-Aug R.LFPPQWIC[160.03]C[160.03]DIR[166.11].Y sp|Q86U44|MTA70_HUMAN 1 1613.7722 0.01 21640 22846 2 1613.771951 807.8934 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 5.82 3754.6 - 5.90E+07 - - - -0.1605 - 1.777 0.544 - 169.4 1 2 0 -0.0003 12 0 0 0 6.71E+06 5.65E+08 - - - 4.5716 1 221125_WJC_METTL3_EV_vs_WT_F02.22847.22847.3 7.75E-07 13/44 R.LFPPQWIC[160.03]C[160.03]DIR[166.11].Y sp|Q86U44|MTA70_HUMAN 1 1613.7722 0.02 21641 22847 3 1613.772141 538.9313 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 5.82 3754.6 - 1.96E+07 - - - -0.0428 - 2.345 0.554 - 205.3 1 2 0 -0.0001 12 0 0 0 2.53E+06 1.38E+08 - - - 7.0789 1 221125_WJC_METTL3_EV_vs_WT_F02.22848.22848.3 1.51E-09 19/68 M.PGIVELPTLEELKVDEVK.L sp|P51970|NDUA8_HUMAN 1 2007.114 0.88 21642 22848 3 2007.115321 670.0453 NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 8 OS=Homo sapiens OX=9606 GN=NDUFA8 PE=1 SV=3 4.25 3754.7 - 4.49E+06 - - - 0.6711 - 3.41 0.603 - 468 1 2 1 0.0013 18 0 0 0 4.16E+07 4.74E+07 - - - 8.3171 1 221125_WJC_METTL3_EV_vs_WT_F02.22850.22850.3 4.04E-10 17/76 K.VLVALYEEPEKPNSALDFLK.H "sp|Q99417|MYCBP_HUMAN,tr|A0A087WV05|A0A087WV05_HUMAN" 2 2274.2148 2.19 21644 22850 3 2274.215801 759.0789 c-Myc-binding protein OS=Homo sapiens OX=9606 GN=MYCBP PE=1 SV=3 4.41 3754.8 - 3.84E+06 - - - 0.4617 - 3.346 0.584 - 276.6 1 2 0 0.001 20 0 0 0 8.69E+07 3.96E+07 - - - 7.9808 1 221125_WJC_METTL3_EV_vs_WT_F02.22854.22854.2 5.75E-09 16/30 K.AVPWVILSDGDGTVEK.G "sp|Q8WVQ1|CANT1_HUMAN,tr|K7EN15|K7EN15_HUMAN" 2 1684.8672 0.96 21648 22854 2 1684.879173 843.4409 Soluble calcium-activated nucleotidase 1 OS=Homo sapiens OX=9606 GN=CANT1 PE=1 SV=1 4.03 3755.2 - 943988 - - - 7.105 - 2.522 0.615 - 556.6 1 2 0 0.012 16 0 0 0 1.06E+07 1.10E+07 - - - 5.8539 1 221125_WJC_METTL3_EV_vs_WT_F02.22863.22863.3 9.79E-06 22/76 K.VLVALYEEPEK[136.11]PNSALDFLK[136.11].H "sp|Q99417|MYCBP_HUMAN,tr|A0A087WV05|A0A087WV05_HUMAN" 2 2290.2432 2.18 21654 22863 3 2290.242511 764.4217 c-Myc-binding protein OS=Homo sapiens OX=9606 GN=MYCBP PE=1 SV=3 4.41 3756.3 - 3.95E+06 - - - -0.2794 - 3.841 0.548 - 395 1 2 0 -0.0006 20 0 0 0 8.65E+07 3.96E+07 - - - 7.9143 1 221125_WJC_METTL3_EV_vs_WT_F02.22864.22864.3 3.29E-08 23/68 M.PGIVELPTLEELK[136.11]VDEVK[136.11].L sp|P51970|NDUA8_HUMAN 1 2023.1424 1.28 21655 22864 3 2023.142517 675.3881 NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 8 OS=Homo sapiens OX=9606 GN=NDUFA8 PE=1 SV=3 4.25 3756.3 - 3.48E+06 - - - 0.0707 - 4.132 0.584 - 699.7 1 2 1 0.0001 18 0 0 0 3.41E+07 2.66E+07 - - - 8.5838 0.9994 221125_WJC_METTL3_EV_vs_WT_F02.22865.22865.2 1.42E-07 22-Nov R.IMVANIEEVLQR.G "sp|O75396|SC22B_HUMAN,tr|A0A087X1A9|A0A087X1A9_HUMAN" 2 1413.765 92.15 21656 22865 2 1413.769146 707.8898 Vesicle-trafficking protein SEC22b OS=Homo sapiens OX=9606 GN=SEC22B PE=1 SV=5 4.53 3756.4 - 3.19E+06 - - - 2.9432 - 2.811 0.384 - 496.5 1 2 0 0.0042 12 0 0 0 1.35E+08 1.47E+06 - - - 4.5953 0.9997 221125_WJC_METTL3_EV_vs_WT_F02.22866.22866.3 0.00159 Oct-60 K.VLLSEFRPSGELFAIK.A "sp|Q16512|PKN1_HUMAN,tr|K7EL10|K7EL10_HUMAN" 2 1805.0087 2.19 21657 22866 3 1805.009919 602.6769 Serine\threonine-protein kinase N1 OS=Homo sapiens OX=9606 GN=PKN1 PE=1 SV=2 6.11 3756.5 - 2.45E+06 - - - 0.6637 - 1.967 0.359 - 102.9 1 2 0 0.0012 16 0 0 0 2.54E+07 1.16E+07 - - - 4.278 0.9997 221125_WJC_METTL3_EV_vs_WT_F02.22867.22867.2 0.00051 18-Nov K.TLQIFNIEMK[136.11].S "sp|Q00610|CLH1_HUMAN,sp|P53675|CLH2_HUMAN,tr|J3KSQ2|J3KSQ2_HUMAN,tr|J3KS13|J3KS13_HUMAN,tr|A0A087WVQ6|A0A087WVQ6_HUMAN,tr|F5H5N6|F5H5N6_HUMAN,tr|A0A087WX41|A0A087WX41_HUMAN" 7 1243.6726 1 21658 22867 2 1243.674444 622.8436 Clathrin heavy chain 1 OS=Homo sapiens OX=9606 GN=CLTC PE=1 SV=5 5.66 3756.5 - 1.95E+06 - - - 1.4867 - 2.236 0.394 - 342.7 1 2 0 0.0018 10 0 0 0 3.98E+07 3.97E+07 - - - 4.1966 0.9997 221125_WJC_METTL3_EV_vs_WT_F02.22868.22868.2 7.02E-05 18-Oct K.TLQIFNIEMK.S "sp|Q00610|CLH1_HUMAN,sp|P53675|CLH2_HUMAN,tr|J3KSQ2|J3KSQ2_HUMAN,tr|J3KS13|J3KS13_HUMAN,tr|A0A087WVQ6|A0A087WVQ6_HUMAN,tr|F5H5N6|F5H5N6_HUMAN,tr|A0A087WX41|A0A087WX41_HUMAN" 7 1235.6584 1 21659 22868 2 1235.658385 618.8365 Clathrin heavy chain 1 OS=Homo sapiens OX=9606 GN=CLTC PE=1 SV=5 5.66 3756.7 - 1.73E+06 - - - -0.0081 - 2.096 0.328 - 276.9 1 2 0 0 10 0 0 0 3.98E+07 3.97E+07 - - - 3.5293 0.9987 221125_WJC_METTL3_EV_vs_WT_F02.22870.22870.2 0.00028 22-Nov R.LFPPQWIC[160.03]C[160.03]DIR.Y sp|Q86U44|MTA70_HUMAN 1 1603.7639 0.01 21661 22870 2 1603.770394 802.8892 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 5.82 3756.9 - 1.67E+06 - - - 4.0243 - 2.086 0.497 - 369.3 1 2 0 0.0065 12 0 0 0 6.71E+06 5.59E+08 - - - 4.6444 1 221125_WJC_METTL3_EV_vs_WT_F02.22871.22871.2 2.66E-06 15/30 -.MVGQLSEGAIAAIMQK.G sp|P27694|RFA1_HUMAN 1 1645.8531 1.91 21662 22871 2 1645.850741 823.9339 Replication protein A 70 kDa DNA-binding subunit OS=Homo sapiens OX=9606 GN=RPA1 PE=1 SV=2 5.75 3757 - 1.48E+06 - - - -1.4631 - 3.037 0.539 - 659.8 1 2 0 -0.0024 16 0 0 0 1.11E+07 5.81E+06 - - - 5.7524 0.9998 221125_WJC_METTL3_EV_vs_WT_F02.22873.22873.2 0.00153 22-Dec K.QVIPETLLSWQR.V sp|Q6P4A8|PLBL1_HUMAN 1 1468.8038 999 21664 22873 2 1468.805015 735.4092 Phospholipase B-like 1 OS=Homo sapiens OX=9606 GN=PLBD1 PE=1 SV=2 6 3757.3 - 1.16E+06 - - - 0.8177 - 2.259 0.451 - 360.2 1 2 0 0.0012 12 0 0 0 1.08E+07 0.00E+00 - - - 4.5159 0.9994 221125_WJC_METTL3_EV_vs_WT_F02.22874.22874.3 0.000304 13/44 R.IMVANIEEVLQR.G "sp|O75396|SC22B_HUMAN,tr|A0A087X1A9|A0A087X1A9_HUMAN" 2 1413.765 2.67 21665 22874 3 1413.76813 472.2623 Vesicle-trafficking protein SEC22b OS=Homo sapiens OX=9606 GN=SEC22B PE=1 SV=5 4.53 3757.4 - 1.08E+06 - - - 2.2246 - 2.673 0.272 - 244.9 1 2 0 0.0031 12 0 0 0 5.04E+06 1.89E+06 - - - 4.297 0.9998 221125_WJC_METTL3_EV_vs_WT_F02.22875.22875.3 3.81E-07 17/60 K.LLLFDYDK[136.11]VELANMNR[166.11].L "sp|Q9GZZ9|UBA5_HUMAN,tr|E7EWE1|E7EWE1_HUMAN,tr|C9JRV9|C9JRV9_HUMAN,tr|C9J0F6|C9J0F6_HUMAN,tr|A0A804HJ86|A0A804HJ86_HUMAN,tr|C9J5W5|C9J5W5_HUMAN,tr|E7EQ61|E7EQ61_HUMAN" 7 1971.0255 0.27 21666 22875 3 1971.025186 658.0158 Ubiquitin-like modifier-activating enzyme 5 OS=Homo sapiens OX=9606 GN=UBA5 PE=1 SV=1 4.56 3757.6 - 1.04E+06 - - - -0.136 - 2.667 0.448 - 389.5 1 2 1 -0.0003 16 0 0 0 2.34E+06 8.73E+06 - - - 6.0517 0.9991 221125_WJC_METTL3_EV_vs_WT_F02.22876.22876.3 0.00935 Oct-44 K.LESALTELEQLR.K sp|P12270|TPR_HUMAN 1 1400.7511 0.38 21667 22876 3 1400.751779 467.9243 Nucleoprotein TPR OS=Homo sapiens OX=9606 GN=TPR PE=1 SV=3 4.25 3757.7 - 942909 - - - 0.4783 - 2.127 0.247 - 221.3 1 2 0 0.0007 12 0 0 0 6.83E+06 1.79E+07 - - - 3.3856 0.9996 221125_WJC_METTL3_EV_vs_WT_F02.22877.22877.3 0.00459 Dec-60 -.MVGQLSEGAIAAIMQK[136.11].G sp|P27694|RFA1_HUMAN 1 1653.8673 1.65 21668 22877 3 1653.867332 552.2964 Replication protein A 70 kDa DNA-binding subunit OS=Homo sapiens OX=9606 GN=RPA1 PE=1 SV=2 5.75 3757.7 - 902901 - - - -0.0103 - 1.964 0.333 - 123.9 1 2 0 0 16 0 0 0 7.76E+06 4.70E+06 - - - 3.9845 1 221125_WJC_METTL3_EV_vs_WT_F02.22879.22879.2 1.25E-08 17/34 R.WVTTASLLDYDTVAGADK[136.11].F sp|Q15393|SF3B3_HUMAN 1 1932.956 1.37 21670 22879 2 1932.963056 967.4853 Splicing factor 3B subunit 3 OS=Homo sapiens OX=9606 GN=SF3B3 PE=1 SV=4 3.93 3758 - 671728 - - - 3.638 - 3.314 0.613 - 715.7 1 2 0 0.007 18 0 0 0 1.99E+07 1.45E+07 - - - 6.5121 0.9274 221125_WJC_METTL3_EV_vs_WT_F02.22880.22880.2 0.000204 Oct-34 K.AIGAVPLIQGEYMIPC[160.03]EK[136.11].V "sp|P07339|CATD_HUMAN,tr|A0A1B0GW44|A0A1B0GW44_HUMAN,tr|A0A1B0GVD5|A0A1B0GVD5_HUMAN,tr|A0A1B0GV23|A0A1B0GV23_HUMAN,tr|C9JH19|C9JH19_HUMAN,tr|H7C469|H7C469_HUMAN,tr|A0A1B0GWE8|A0A1B0GWE8_HUMAN,tr|A0A1B0GU03|A0A1B0GU03_HUMAN,tr|A0A1B0GU92|A0A1B0GU92_HUMAN,tr|F8W787|F8W787_HUMAN" 10 1996.0253 5.32 21671 22880 2 1997.022039 999.0199 Cathepsin D OS=Homo sapiens OX=9606 GN=CTSD PE=1 SV=1 4.53 3758.1 - 640995 - - - 499.3589 - 2.046 0.4 - 205.9 1 2 0 0.9967 18 0 0 0 2.03E+07 3.81E+06 - - - 3.4425 0.9782 221125_WJC_METTL3_EV_vs_WT_F02.22883.22883.3 0.754 Nov-60 K.VLLSEFR[166.11]PSGELFAIK[136.11].A "sp|Q16512|PKN1_HUMAN,tr|K7EL10|K7EL10_HUMAN" 2 1823.0312 2.19 21673 22883 3 1823.029964 608.6843 Serine\threonine-protein kinase N1 OS=Homo sapiens OX=9606 GN=PKN1 PE=1 SV=2 6.11 3758.5 - 743641 - - - -0.6731 - 1.43 0.169 - 101.4 1 2 0 -0.0012 16 0 0 0 2.54E+07 1.16E+07 - - - 1.3416 0.9401 221125_WJC_METTL3_EV_vs_WT_F02.22884.22884.2 0.324 30-Jul K.AVPWVILSDGDGTVEK[136.11].G "sp|Q8WVQ1|CANT1_HUMAN,tr|K7EN15|K7EN15_HUMAN" 2 1692.8814 1.01 21674 22884 2 1692.88686 847.448 Soluble calcium-activated nucleotidase 1 OS=Homo sapiens OX=9606 GN=CANT1 PE=1 SV=1 4.03 3758.6 - 584478 - - - 3.2241 - 1.464 0.136 - 44 11 2 0 0.0055 16 0 0 0 1.06E+07 1.06E+07 - - - 0.5157 0.9176 221125_WJC_METTL3_EV_vs_WT_F02.22885.22885.2 0.11 14-Aug K.DIGFIK[136.11]LD.- "sp|P62273|RS29_HUMAN,tr|A0A087WTT6|A0A087WTT6_HUMAN" 2 927.5157 1.06 21675 22885 2 927.515356 464.7651 40S ribosomal protein S29 OS=Homo sapiens OX=9606 GN=RPS29 PE=1 SV=2 4.54 3758.7 - 4.77E+06 - - - -0.3536 - 1.006 0.233 - 114 1 2 1 -0.0003 8 0 0 0 1.14E+09 1.08E+09 - - - 0.7799 0.9474 221125_WJC_METTL3_EV_vs_WT_F02.22886.22886.2 0.252 14-Jun K.DIGFIKLD.- "sp|P62273|RS29_HUMAN,tr|A0A087WTT6|A0A087WTT6_HUMAN" 2 919.5015 1.06 21676 22886 2 919.500973 460.758 40S ribosomal protein S29 OS=Homo sapiens OX=9606 GN=RPS29 PE=1 SV=2 4.54 3758.7 - 4.47E+06 - - - -0.5557 - 1.087 0.279 - 57.7 3 2 1 -0.0005 8 0 0 0 1.14E+09 1.08E+09 - - - 1.14 0.9996 221125_WJC_METTL3_EV_vs_WT_F02.22888.22888.3 0.00667 Dec-52 R.ELDSITPEVLPGWK[136.11].G "sp|Q16891|MIC60_HUMAN,tr|B9A067|B9A067_HUMAN,tr|C9J406|C9J406_HUMAN,tr|H7C463|H7C463_HUMAN" 4 1590.8385 1.46 21678 22888 3 1590.836045 531.2868 MICOS complex subunit MIC60 OS=Homo sapiens OX=9606 GN=IMMT PE=1 SV=1 4.14 3758.9 - 2.16E+06 - - - -1.5269 - 2.095 0.334 - 125.9 1 2 0 -0.0024 14 0 0 0 2.71E+07 1.85E+07 - - - 4.2285 1 221125_WJC_METTL3_EV_vs_WT_F02.22890.22890.3 9.38E-08 23/64 K.C[160.03]PSIAAAIAAVNALHGR.W sp|Q14498|RBM39_HUMAN 1 1690.8937 1.27 21680 22890 3 1690.895137 564.6385 RNA-binding protein 39 OS=Homo sapiens OX=9606 GN=RBM39 PE=1 SV=2 8.26 3759 - 1.58E+06 - - - 0.8451 - 4.337 0.607 - 776.3 1 2 0 0.0014 17 0 0 0 2.08E+07 1.64E+07 - - - 9.0136 1 221125_WJC_METTL3_EV_vs_WT_F02.22891.22891.2 5.14E-10 20/34 R.WVTTASLLDYDTVAGADK.F sp|Q15393|SF3B3_HUMAN 1 1924.9418 1.37 21681 22891 2 1924.941343 963.4782 Splicing factor 3B subunit 3 OS=Homo sapiens OX=9606 GN=SF3B3 PE=1 SV=4 3.93 3759.2 - 1.57E+06 - - - -0.2499 - 3.75 0.685 - 1162.2 1 2 0 -0.0005 18 0 0 0 1.99E+07 1.45E+07 - - - 7.3499 0.9997 221125_WJC_METTL3_EV_vs_WT_F02.22893.22893.2 1.78E-05 15/28 R.DYLHLPPEIVPATLR[166.11].R "sp|P46783|RS10_HUMAN,tr|A0A2R8Y6L3|A0A2R8Y6L3_HUMAN,tr|F6U211|F6U211_HUMAN,tr|A0A1W2PQS6|A0A1W2PQS6_HUMAN,tr|A0A2R8YFH6|A0A2R8YFH6_HUMAN,tr|A0A2R8Y7H1|A0A2R8Y7H1_HUMAN,tr|S4R435|S4R435_HUMAN" 7 1742.9595 1.34 21683 22893 2 1742.962745 872.487 40S ribosomal protein S10 OS=Homo sapiens OX=9606 GN=RPS10 PE=1 SV=1 5.32 3759.4 - 1.18E+06 - - - 1.8755 - 2.269 0.473 - 440.1 1 2 0 0.0033 15 0 0 0 3.16E+08 2.36E+08 - - - 4.5479 0.9998 221125_WJC_METTL3_EV_vs_WT_F02.22895.22895.2 0.000523 28-Nov R.DYLHLPPEIVPATLR.R "sp|P46783|RS10_HUMAN,tr|A0A2R8Y6L3|A0A2R8Y6L3_HUMAN,tr|F6U211|F6U211_HUMAN,tr|A0A1W2PQS6|A0A1W2PQS6_HUMAN,tr|A0A2R8YFH6|A0A2R8YFH6_HUMAN,tr|A0A2R8Y7H1|A0A2R8Y7H1_HUMAN,tr|S4R435|S4R435_HUMAN" 7 1732.9512 1.3 21685 22895 2 1732.949655 867.4829 40S ribosomal protein S10 OS=Homo sapiens OX=9606 GN=RPS10 PE=1 SV=1 5.32 3759.6 - 859856 - - - -0.895 - 2.169 0.434 - 123.8 1 2 0 -0.0016 15 0 0 0 2.79E+08 2.14E+08 - - - 4.1496 0.9998 221125_WJC_METTL3_EV_vs_WT_F02.22898.22898.3 0.000427 16/64 K.FLSAIVSSVDK[136.11]IPYGMR[166.11].F "sp|P46940|IQGA1_HUMAN,tr|H0YLE8|H0YLE8_HUMAN,tr|A0A0J9YXZ5|A0A0J9YXZ5_HUMAN" 3 1900.0247 0.001 21688 22898 3 1900.02178 634.3489 Ras GTPase-activating-like protein IQGAP1 OS=Homo sapiens OX=9606 GN=IQGAP1 PE=1 SV=1 8.59 3759.9 - 592494 - - - -1.5505 - 2.812 0.48 - 252.7 1 2 1 -0.0029 17 0 0 0 0.00E+00 2.61E+06 - - - 6.5026 1 221125_WJC_METTL3_EV_vs_WT_F02.22899.22899.2 2.73E-10 15/26 R.QYATLDVYNPFETR[166.11].E sp|O14828|SCAM3_HUMAN 1 1725.8238 1.18 21689 22899 2 1725.821489 863.9192 Secretory carrier-associated membrane protein 3 OS=Homo sapiens OX=9606 GN=SCAMP3 PE=1 SV=3 4.37 3760.1 - 509592 - - - -1.3223 - 2.982 0.622 - 1076 1 2 0 -0.0023 14 0 0 0 4.65E+07 3.94E+07 - - - 6.3762 0.9785 221125_WJC_METTL3_EV_vs_WT_F02.22903.22903.3 0.148 Nov-52 R.IALLPLLQAETDR[166.11]R[166.11].T "sp|Q9P0J0|NDUAD_HUMAN,tr|B4DEZ3|B4DEZ3_HUMAN,tr|E7ENQ6|E7ENQ6_HUMAN,tr|K7EJE1|K7EJE1_HUMAN,tr|U3KQP3|U3KQP3_HUMAN" 5 1627.9524 1.41 21691 22903 3 1627.951763 543.6581 NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 13 OS=Homo sapiens OX=9606 GN=NDUFA13 PE=1 SV=3 6.07 3760.6 - 1.80E+06 - - - -0.4103 - 1.933 0.095 - 210.4 1 2 0 -0.0007 14 0 0 0 4.89E+07 3.46E+07 - - - 1.3505 1 221125_WJC_METTL3_EV_vs_WT_F02.22904.22904.2 5.63E-11 16/26 R.QYATLDVYNPFETR.E sp|O14828|SCAM3_HUMAN 1 1715.8155 1.18 21692 22904 2 1715.813788 858.915 Secretory carrier-associated membrane protein 3 OS=Homo sapiens OX=9606 GN=SCAMP3 PE=1 SV=3 4.37 3760.7 - 939872 - - - -0.9984 - 3.146 0.637 - 1242.4 1 2 0 -0.0017 14 0 0 0 4.65E+07 3.94E+07 - - - 6.6215 1 221125_WJC_METTL3_EV_vs_WT_F02.22907.22907.3 4.87E-10 17/64 R.HILLAVANDEELNQLLK[136.11].G "sp|Q9P0M6|H2AW_HUMAN,sp|O75367|H2AY_HUMAN,tr|A0A7I2V3R0|A0A7I2V3R0_HUMAN,tr|A0A7I2YQD6|A0A7I2YQD6_HUMAN,tr|A0A7I2V412|A0A7I2V412_HUMAN,tr|A0A7I2V423|A0A7I2V423_HUMAN,tr|A0A7I2V2N7|A0A7I2V2N7_HUMAN,tr|D6RCF2|D6RCF2_HUMAN,tr|A0A7I2V6E9|A0A7I2V6E9_HUMAN,tr|A0A7I2YQR8|A0A7I2YQR8_HUMAN" 10 1940.0822 1.38 21695 22907 3 1940.08137 647.7014 Core histone macro-H2A.2 OS=Homo sapiens OX=9606 GN=MACROH2A2 PE=1 SV=3 4.65 3761 - 1.42E+06 - - - -0.4417 - 3.434 0.575 - 414.9 1 2 0 -0.0009 17 0 0 0 8.30E+06 6.03E+06 - - - 8.0672 1 221125_WJC_METTL3_EV_vs_WT_F02.22908.22908.3 2.67E-11 19/88 R.VVLPC[160.03]SVQEYQVGQLYSVAEASK[136.11].N "sp|P48739|PIPNB_HUMAN,tr|B3KYB7|B3KYB7_HUMAN,tr|A0A0A0MSW4|A0A0A0MSW4_HUMAN" 3 2561.2927 0.99 21696 22908 3 2561.293407 854.7715 Phosphatidylinositol transfer protein beta isoform OS=Homo sapiens OX=9606 GN=PITPNB PE=1 SV=2 4.53 3761.1 - 1.37E+06 - - - 0.2795 - 3.775 0.637 - 383.9 1 2 0 0.0007 23 0 0 0 7.57E+06 7.68E+06 - - - 8.7581 1 221125_WJC_METTL3_EV_vs_WT_F02.22909.22909.2 1.29E-09 17/30 R.ESFSLVQVQPGVDIIR[166.11].T "sp|P46379|BAG6_HUMAN,tr|A0A7I2V508|A0A7I2V508_HUMAN,tr|A0A7P0MQS5|A0A7P0MQS5_HUMAN,tr|A0A0G2JL47|A0A0G2JL47_HUMAN,tr|A0A024RCR6|A0A024RCR6_HUMAN,tr|A0A0G2JK23|A0A0G2JK23_HUMAN" 6 1795.9708 2.2 21697 22909 2 1795.969487 898.9927 Large proline-rich protein BAG6 OS=Homo sapiens OX=9606 GN=BAG6 PE=1 SV=2 4.37 3761.2 - 1.35E+06 - - - -0.7138 - 3.337 0.594 - 808.2 1 2 0 -0.0013 16 0 0 0 4.29E+07 1.95E+07 - - - 6.3906 0.9998 221125_WJC_METTL3_EV_vs_WT_F02.22910.22910.2 0.0268 22-Nov K.TDYIPLLDVDEK[136.11].T "sp|P27816|MAP4_HUMAN,tr|E7EVA0|E7EVA0_HUMAN,tr|A0A0J9YVV8|A0A0J9YVV8_HUMAN,tr|H7C456|H7C456_HUMAN,tr|A0A0J9YW37|A0A0J9YW37_HUMAN,tr|A0A804HKE7|A0A804HKE7_HUMAN" 6 1427.7275 1.07 21698 22910 2 1427.728682 714.871 Microtubule-associated protein 4 OS=Homo sapiens OX=9606 GN=MAP4 PE=1 SV=3 3.84 3761.4 - 1.18E+06 - - - 0.809 - 2.046 0.43 - 237.3 1 2 0 0.0012 12 0 0 0 1.46E+07 1.37E+07 - - - 4.1002 0.9986 221125_WJC_METTL3_EV_vs_WT_F02.22916.22916.2 0.000315 16-Oct K.DLFQVAFNR[166.11].V "sp|Q14204|DYHC1_HUMAN,tr|A0A7P0T8N2|A0A7P0T8N2_HUMAN,tr|A0A7P0T9C4|A0A7P0T9C4_HUMAN,tr|A0A7P0TBJ7|A0A7P0TBJ7_HUMAN,tr|A0A7P0T9K2|A0A7P0T9K2_HUMAN,tr|A0A2R8Y706|A0A2R8Y706_HUMAN,tr|A0A7P0T916|A0A7P0T916_HUMAN,tr|A0A7P0TB75|A0A7P0TB75_HUMAN,tr|A0A7P0TAF3|A0A7P0TAF3_HUMAN,tr|A0A7P0TAW9|A0A7P0TAW9_HUMAN,tr|A0A7P0TA13|A0A7P0TA13_HUMAN,tr|A0A7P0T7V5|A0A7P0T7V5_HUMAN,tr|A0A7P0T9R4|A0A7P0T9R4_HUMAN,tr|A0A2R8Y5T0|A0A2R8Y5T0_HUMAN,tr|A0A2R8Y6H2|A0A2R8Y6H2_HUMAN" 15 1118.5748 0.49 21704 22916 2 1118.570983 560.2947 Cytoplasmic dynein 1 heavy chain 1 OS=Homo sapiens OX=9606 GN=DYNC1H1 PE=1 SV=5 5.84 3762.1 - 762568 - - - -3.424 - 1.854 0.421 - 308.6 1 2 0 -0.0038 9 0 0 0 5.24E+06 1.07E+07 - - - 3.9353 0.9999 221125_WJC_METTL3_EV_vs_WT_F02.22917.22917.3 0.00132 17/52 R.GIEK[136.11]PPFELPDFIK[136.11].R "sp|Q13435|SF3B2_HUMAN,tr|E9PPJ0|E9PPJ0_HUMAN" 2 1644.9098 1.64 21705 22917 3 1644.909261 549.3105 Splicing factor 3B subunit 2 OS=Homo sapiens OX=9606 GN=SF3B2 PE=1 SV=2 4.68 3762.2 - 755818 - - - -0.3246 - 2.6 0.338 - 304.7 1 2 0 -0.0005 14 0 0 0 7.39E+07 4.51E+07 - - - 4.8475 1 221125_WJC_METTL3_EV_vs_WT_F02.22923.22923.2 0.00046 17/30 R.ESFSLVQVQPGVDIIR.T "sp|P46379|BAG6_HUMAN,tr|A0A7I2V508|A0A7I2V508_HUMAN,tr|A0A7P0MQS5|A0A7P0MQS5_HUMAN,tr|A0A0G2JL47|A0A0G2JL47_HUMAN,tr|A0A024RCR6|A0A024RCR6_HUMAN,tr|A0A0G2JK23|A0A0G2JK23_HUMAN" 6 1785.9625 2.2 21709 22923 2 1785.961752 893.9885 Large proline-rich protein BAG6 OS=Homo sapiens OX=9606 GN=BAG6 PE=1 SV=2 4.37 3762.9 - 2.57E+06 - - - -0.4183 - 2.979 0.59 - 809 1 2 0 -0.0007 16 0 0 0 4.29E+07 1.95E+07 - - - 6.0822 0.9999 221125_WJC_METTL3_EV_vs_WT_F02.22924.22924.2 2.52E-05 22-Dec K.DAGTIAGLNVLR[166.11].L "sp|P11142|HSP7C_HUMAN,tr|E9PQQ4|E9PQQ4_HUMAN,tr|E9PKE3|E9PKE3_HUMAN,tr|E9PN89|E9PN89_HUMAN,tr|E9PLF4|E9PLF4_HUMAN,tr|E9PI65|E9PI65_HUMAN,tr|E9PK54|E9PK54_HUMAN,tr|E9PQK7|E9PQK7_HUMAN" 8 1208.6753 0.13 21710 22924 2 1208.675147 605.3449 Heat shock cognate 71 kDa protein OS=Homo sapiens OX=9606 GN=HSPA8 PE=1 SV=1 5.84 3762.9 - 7.09E+06 - - - -0.0902 - 2.475 0.53 - 502.7 1 2 0 -0.0001 12 0 0 0 1.39E+07 1.05E+08 - - - 5.34 1 221125_WJC_METTL3_EV_vs_WT_F02.22925.22925.3 0.00119 22/64 R.SYTGLAPGYTYQFPEFR.V sp|O43347|MSI1H_HUMAN 1 1995.9367 1.55 21711 22925 3 1995.937559 666.3195 RNA-binding protein Musashi homolog 1 OS=Homo sapiens OX=9606 GN=MSI1 PE=1 SV=1 5.72 3763 - 2.29E+06 - - - 0.4409 - 2.976 0.536 - 284 1 2 0 0.0009 17 0 0 0 2.99E+08 1.93E+08 - - - 7.2708 1 221125_WJC_METTL3_EV_vs_WT_F02.22926.22926.2 2.53E-08 16/32 R.SYTGLAPGYTYQFPEFR.V sp|O43347|MSI1H_HUMAN 1 1995.9367 1.44 21712 22926 2 1995.93406 998.9756 RNA-binding protein Musashi homolog 1 OS=Homo sapiens OX=9606 GN=MSI1 PE=1 SV=1 5.72 3763.1 - 2.02E+06 - - - -1.3122 - 3.103 0.667 - 468.9 1 2 0 -0.0026 17 0 0 0 3.74E+08 2.60E+08 - - - 6.7506 0.9997 221125_WJC_METTL3_EV_vs_WT_F02.22927.22927.3 0.000814 Dec-60 R.ESFSLVQVQPGVDIIR.T "sp|P46379|BAG6_HUMAN,tr|A0A7I2V508|A0A7I2V508_HUMAN,tr|A0A7P0MQS5|A0A7P0MQS5_HUMAN,tr|A0A0G2JL47|A0A0G2JL47_HUMAN,tr|A0A024RCR6|A0A024RCR6_HUMAN,tr|A0A0G2JK23|A0A0G2JK23_HUMAN" 6 1785.9625 2.48 21713 22927 3 1785.966423 596.3281 Large proline-rich protein BAG6 OS=Homo sapiens OX=9606 GN=BAG6 PE=1 SV=2 4.37 3763.2 - 1.86E+06 - - - 2.1971 - 2.387 0.385 - 116.9 1 2 0 0.0039 16 0 0 0 2.26E+07 9.14E+06 - - - 5.0637 1 221125_WJC_METTL3_EV_vs_WT_F02.22928.22928.2 3.81E-06 19/32 R.SYTGLAPGYTYQFPEFR[166.11].V sp|O43347|MSI1H_HUMAN 1 2005.9449 1.44 21714 22928 2 2005.942718 1003.9798 RNA-binding protein Musashi homolog 1 OS=Homo sapiens OX=9606 GN=MSI1 PE=1 SV=1 5.72 3763.3 - 1.73E+06 - - - -1.1122 - 3.534 0.626 - 727 1 2 0 -0.0022 17 0 0 0 3.74E+08 2.60E+08 - - - 6.7677 1 221125_WJC_METTL3_EV_vs_WT_F02.22929.22929.3 0.000342 17/52 R.GIITWGLLPGPYHR.G "sp|Q9BUK6|MSTO1_HUMAN,tr|A0A3B3IUD2|A0A3B3IUD2_HUMAN" 2 1578.8671 1.53 21715 22929 3 1578.867473 527.2963 Protein misato homolog 1 OS=Homo sapiens OX=9606 GN=MSTO1 PE=1 SV=1 8.75 3763.4 - 1.52E+06 - - - 0.247 - 3.135 0.436 - 378.1 1 2 0 0.0004 14 0 0 0 1.61E+07 1.05E+07 - - - 6.4374 0.997 221125_WJC_METTL3_EV_vs_WT_F02.22930.22930.3 8.21E-07 23/64 L.QLVEPFGVISNHLILNK[136.11].L "sp|P43243|MATR3_HUMAN,tr|D6RE02|D6RE02_HUMAN,tr|B3KM87|B3KM87_HUMAN,tr|A8MXP9|A8MXP9_HUMAN,tr|D6R991|D6R991_HUMAN,tr|D6RBK5|D6RBK5_HUMAN,tr|A0A0R4J2E8|A0A0R4J2E8_HUMAN,tr|D6RIA2|D6RIA2_HUMAN,tr|H0Y8T4|H0Y8T4_HUMAN,tr|D6REM6|D6REM6_HUMAN,tr|D6RBI2|D6RBI2_HUMAN" 11 1928.0975 1.45 21716 22930 3 1928.100688 643.7064 Matrin-3 OS=Homo sapiens OX=9606 GN=MATR3 PE=1 SV=2 6.75 3763.5 - 1.40E+06 - - - 1.6623 - 3.439 0.495 - 444.6 1 1 0 0.0032 17 0 0 0 9.25E+07 6.36E+07 - - - 7.1783 0.9999 221125_WJC_METTL3_EV_vs_WT_F02.22931.22931.3 0.0192 15/44 K.VESLQEEIAFLK.K "sp|P08670|VIME_HUMAN,tr|B0YJC5|B0YJC5_HUMAN,tr|B0YJC4|B0YJC4_HUMAN" 3 1404.75 1.46 21717 22931 3 1404.748315 469.2573 Vimentin OS=Homo sapiens OX=9606 GN=VIM PE=1 SV=4 4.25 3763.6 - 1.35E+06 - - - -1.233 - 2.563 0.36 - 320.6 1 2 0 -0.0017 12 0 0 0 1.38E+07 9.45E+06 - - - 5.162 1 221125_WJC_METTL3_EV_vs_WT_F02.22935.22935.2 3.47E-08 18/38 R.YGAASGVVPGSLWPSPEQLR.E sp|Q8TAE8|G45IP_HUMAN 1 2070.0534 9.48 21721 22935 2 2070.049813 1036.034 Growth arrest and DNA damage-inducible proteins-interacting protein 1 OS=Homo sapiens OX=9606 GN=GADD45GIP1 PE=1 SV=1 6 3764.1 - 557782 - - - -1.7521 - 3.773 0.62 - 476.9 1 2 0 -0.0036 20 0 0 0 1.79E+07 1.89E+06 - - - 6.8838 0.9999 221125_WJC_METTL3_EV_vs_WT_F02.22938.22938.2 0.00942 22-Dec K.VESLQEEIAFLK.K "sp|P08670|VIME_HUMAN,tr|B0YJC5|B0YJC5_HUMAN,tr|B0YJC4|B0YJC4_HUMAN" 3 1404.75 1.62 21722 22938 2 1404.748602 703.3823 Vimentin OS=Homo sapiens OX=9606 GN=VIM PE=1 SV=4 4.25 3764.5 - 3.00E+07 - - - -1.0287 - 2.675 0.484 - 554.4 1 2 0 -0.0014 12 0 0 0 2.59E+08 1.59E+08 - - - 5.2043 0.9998 221125_WJC_METTL3_EV_vs_WT_F02.22940.22940.2 4.93E-06 16-Sep K.C[160.03]MPTFQFFK[136.11].K sp|P10599|THIO_HUMAN 1 1212.5551 0.68 21724 22940 2 1212.554195 607.2848 Thioredoxin OS=Homo sapiens OX=9606 GN=TXN PE=1 SV=3 8.22 3764.6 - 9.67E+06 - - - -0.7653 - 1.458 0.516 - 192.4 1 2 0 -0.0009 9 0 0 0 8.47E+07 1.25E+08 - - - 3.9428 0.9966 221125_WJC_METTL3_EV_vs_WT_F02.22941.22941.3 3.84E-06 15/64 L.QLVEPFGVISNHLILNK.L "sp|P43243|MATR3_HUMAN,tr|D6RE02|D6RE02_HUMAN,tr|B3KM87|B3KM87_HUMAN,tr|A8MXP9|A8MXP9_HUMAN,tr|D6R991|D6R991_HUMAN,tr|D6RBK5|D6RBK5_HUMAN,tr|A0A0R4J2E8|A0A0R4J2E8_HUMAN,tr|D6RIA2|D6RIA2_HUMAN,tr|H0Y8T4|H0Y8T4_HUMAN,tr|D6REM6|D6REM6_HUMAN,tr|D6RBI2|D6RBI2_HUMAN" 11 1920.0833 1.46 21725 22941 3 1920.083472 641.035 Matrin-3 OS=Homo sapiens OX=9606 GN=MATR3 PE=1 SV=2 6.75 3764.6 - 6.17E+06 - - - 0.0984 - 2.86 0.469 - 286.4 1 1 0 0.0002 17 0 0 0 9.28E+07 6.36E+07 - - - 6.4235 0.9998 221125_WJC_METTL3_EV_vs_WT_F02.22942.22942.2 6.64E-07 16-Sep K.C[160.03]MPTFQFFK.K sp|P10599|THIO_HUMAN 1 1204.5409 0.68 21726 22942 2 1204.538766 603.2777 Thioredoxin OS=Homo sapiens OX=9606 GN=TXN PE=1 SV=3 8.22 3764.7 - 5.79E+06 - - - -1.7907 - 1.79 0.627 - 191.9 1 2 0 -0.0022 9 0 0 0 8.47E+07 1.25E+08 - - - 5.3557 0.9999 221125_WJC_METTL3_EV_vs_WT_F02.22943.22943.2 0.000342 14/22 K.TVTAMDVVYALK[136.11].R sp|P62805|H4_HUMAN 1 1317.7094 0.99 21727 22943 2 1317.708269 659.862 Histone H4 OS=Homo sapiens OX=9606 GN=H4C1 PE=1 SV=2 5.5 3764.7 - 3.82E+06 - - - -0.8393 - 2.614 0.502 - 389.8 1 2 0 -0.0011 12 0 0 0 1.18E+08 1.18E+08 - - - 5.2767 1 221125_WJC_METTL3_EV_vs_WT_F02.22944.22944.3 0.000412 14/44 K.FNFFIHNLAQLR[166.11].F sp|O00443|P3C2A_HUMAN 1 1528.8178 1.53 21728 22944 3 1528.81729 510.6132 Phosphatidylinositol 4-phosphate 3-kinase C2 domain-containing subunit alpha OS=Homo sapiens OX=9606 GN=PIK3C2A PE=1 SV=2 9.76 3764.8 - 3.78E+06 - - - -0.3584 - 2.689 0.5 - 201.7 1 2 0 -0.0005 12 0 0 0 3.04E+07 1.99E+07 - - - 6.8562 0.9999 221125_WJC_METTL3_EV_vs_WT_F02.22945.22945.2 0.000811 15/24 R.ALGTEVIQLFPEK[136.11].G "sp|O95831|AIFM1_HUMAN,tr|A0A6Q8PFW2|A0A6Q8PFW2_HUMAN,tr|A0A6Q8PFA7|A0A6Q8PFA7_HUMAN,tr|A0A6Q8PHJ9|A0A6Q8PHJ9_HUMAN,tr|A0A6Q8PFS4|A0A6Q8PFS4_HUMAN,tr|A0A7I2PK44|A0A7I2PK44_HUMAN,tr|A0A6Q8PG15|A0A6Q8PG15_HUMAN,tr|A0A6Q8PFE1|A0A6Q8PFE1_HUMAN,tr|A0A7I2RLJ8|A0A7I2RLJ8_HUMAN,tr|A0A6Q8PFQ8|A0A6Q8PFQ8_HUMAN,tr|A0A6Q8PHC0|A0A6Q8PHC0_HUMAN,tr|A0A6Q8PFM5|A0A6Q8PFM5_HUMAN" 12 1451.8115 1.48 21729 22945 2 1451.810523 726.913 "Apoptosis-inducing factor 1, mitochondrial OS=Homo sapiens OX=9606 GN=AIFM1 PE=1 SV=1" 4.53 3764.9 - 1.80E+06 - - - -0.6943 - 2.678 0.451 - 726.7 1 2 0 -0.001 13 0 0 0 6.99E+07 4.73E+07 - - - 4.9 1 221125_WJC_METTL3_EV_vs_WT_F02.22948.22948.4 2.86E-08 16/84 R.DYLHLPPEIVPATLR.R "sp|P46783|RS10_HUMAN,tr|A0A2R8Y6L3|A0A2R8Y6L3_HUMAN,tr|F6U211|F6U211_HUMAN,tr|A0A1W2PQS6|A0A1W2PQS6_HUMAN,tr|A0A2R8YFH6|A0A2R8YFH6_HUMAN,tr|A0A2R8Y7H1|A0A2R8Y7H1_HUMAN,tr|S4R435|S4R435_HUMAN" 7 1732.9512 1.4 21732 22948 4 1732.947355 434.2451 40S ribosomal protein S10 OS=Homo sapiens OX=9606 GN=RPS10 PE=1 SV=1 5.32 3765.2 - 956920 - - - -2.2222 - 3.009 0.59 - 185.9 1 2 0 -0.0039 15 0 0 0 1.16E+07 8.26E+06 - - - 4.7545 1 221125_WJC_METTL3_EV_vs_WT_F02.22949.22949.2 7.38E-14 16/30 K.QLDDEEVSEFALDGLK.Q sp|Q92616|GCN1_HUMAN 1 1806.8523 -1 21733 22949 2 1806.850811 904.4334 eIF-2-alpha kinase activator GCN1 OS=Homo sapiens OX=9606 GN=GCN1 PE=1 SV=6 3.71 3765.4 - 818837 - - - -0.8462 - 3.253 0.68 - 881.5 1 2 0 -0.0015 16 0 0 0 0.00E+00 0.00E+00 - - - 6.963 0.9999 221125_WJC_METTL3_EV_vs_WT_F02.22954.22954.3 0.056 16/52 R.GIEKPPFELPDFIK.R "sp|Q13435|SF3B2_HUMAN,tr|E9PPJ0|E9PPJ0_HUMAN" 2 1628.8814 1.22 21736 22954 3 1628.879551 543.9677 Splicing factor 3B subunit 2 OS=Homo sapiens OX=9606 GN=SF3B2 PE=1 SV=2 4.68 3765.9 - 5.04E+06 - - - -1.1321 - 2.675 0.368 - 250.7 1 2 0 -0.0018 14 0 0 0 7.44E+07 6.11E+07 - - - 5.2572 0.9999 221125_WJC_METTL3_EV_vs_WT_F02.22955.22955.2 7.28E-09 15/28 R.GFQFVSSSLPDIC[160.03]YR[166.11].C "sp|P62633|CNBP_HUMAN,tr|D6RAT4|D6RAT4_HUMAN" 2 1784.8431 0.48 21737 22955 2 1784.842444 893.4288 CCHC-type zinc finger nucleic acid binding protein OS=Homo sapiens OX=9606 GN=CNBP PE=1 SV=1 5.83 3766 - 4.07E+06 - - - -0.3821 - 2.865 0.5 - 870.1 1 2 0 -0.0007 15 0 0 0 1.50E+07 3.10E+07 - - - 5.3216 1 221125_WJC_METTL3_EV_vs_WT_F02.22957.22957.2 1.78E-09 22/34 R.IGPYQPNVPVGIDYVIPK.T "sp|P43243|MATR3_HUMAN,tr|B3KM87|B3KM87_HUMAN,tr|A8MXP9|A8MXP9_HUMAN,tr|A0A0R4J2E8|A0A0R4J2E8_HUMAN" 4 1968.072 1.46 21739 22957 2 1968.070121 985.0433 Matrin-3 OS=Homo sapiens OX=9606 GN=MATR3 PE=1 SV=2 5.83 3766.2 - 2.66E+06 - - - -0.9801 - 3.398 0.631 - 1040.5 1 2 0 -0.0019 18 0 0 0 5.17E+09 3.54E+09 - - - 6.7082 1 221125_WJC_METTL3_EV_vs_WT_F02.22959.22959.3 6.81E-09 18/60 K.VYFLPITPHYVTQVIR[166.11].N "sp|P27708|PYR1_HUMAN,tr|F8VPD4|F8VPD4_HUMAN" 2 1955.0908 0.38 21741 22959 3 1955.088772 652.7042 CAD protein OS=Homo sapiens OX=9606 GN=CAD PE=1 SV=3 8.57 3766.4 - 2.17E+06 - - - -1.0501 - 3.369 0.57 - 381.7 1 2 0 -0.0021 16 0 0 0 6.42E+06 1.67E+07 - - - 8.0109 1 221125_WJC_METTL3_EV_vs_WT_F02.22960.22960.2 7.26E-11 21/34 R.IGPYQPNVPVGIDYVIPK[136.11].T "sp|P43243|MATR3_HUMAN,tr|B3KM87|B3KM87_HUMAN,tr|A8MXP9|A8MXP9_HUMAN,tr|A0A0R4J2E8|A0A0R4J2E8_HUMAN" 4 1976.0863 1.46 21742 22960 2 1976.082193 989.0504 Matrin-3 OS=Homo sapiens OX=9606 GN=MATR3 PE=1 SV=2 5.83 3766.5 - 2.07E+06 - - - -2.053 - 3.418 0.666 - 794.9 1 2 0 -0.0041 18 0 0 0 5.17E+09 3.54E+09 - - - 6.9805 1 221125_WJC_METTL3_EV_vs_WT_F02.22961.22961.2 4.49E-11 18/34 R.TVSYNILADTYAQTEFSR.T "sp|Q6L8Q7|PDE12_HUMAN,tr|F6T1Q0|F6T1Q0_HUMAN" 2 2077.9956 1.24 21743 22961 2 2077.992429 1040.0051 "2',5'-phosphodiesterase 12 OS=Homo sapiens OX=9606 GN=PDE12 PE=1 SV=2" 4.37 3766.7 - 1.51E+06 - - - -1.5501 - 3.862 0.647 - 870.7 1 2 0 -0.0032 18 0 0 0 1.32E+07 1.07E+07 - - - 7.1407 1 221125_WJC_METTL3_EV_vs_WT_F02.22963.22963.2 1.43E-07 13/22 K.STQFEYAWC[160.03]LVR[166.11].S sp|Q9Y3D6|FIS1_HUMAN 1 1568.7321 1.27 21745 22963 2 1568.728326 785.3733 Mitochondrial fission 1 protein OS=Homo sapiens OX=9606 GN=FIS1 PE=1 SV=2 5.72 3766.9 - 1.23E+06 - - - -2.4179 - 2.541 0.598 - 767.8 1 2 0 -0.0038 12 0 0 0 2.28E+08 1.80E+08 - - - 5.9104 1 221125_WJC_METTL3_EV_vs_WT_F02.22964.22964.3 3.20E-08 16/52 R.LK[136.11]PGYLEATVDWFR[166.11].R sp|Q15181|IPYR_HUMAN 1 1711.9053 0.48 21746 22964 3 1711.903232 571.6424 Inorganic pyrophosphatase OS=Homo sapiens OX=9606 GN=PPA1 PE=1 SV=2 6.07 3767 - 1.23E+06 - - - -1.1858 - 2.539 0.546 - 269 1 2 0 -0.002 14 0 0 0 1.98E+07 4.11E+07 - - - 7.103 0.9896 221125_WJC_METTL3_EV_vs_WT_F02.22965.22965.2 2.15E-06 24-Dec K.MFFDAELSQMQTH.V "sp|P13647|K2C5_HUMAN,tr|H0YI76|H0YI76_HUMAN,tr|H0YIN9|H0YIN9_HUMAN" 3 1583.6749 - 21747 22965 2 1583.677481 792.8447 "Keratin, type II cytoskeletal 5 OS=Homo sapiens OX=9606 GN=KRT5 PE=1 SV=3" 4.35 3767.2 - 1.08E+06 - - - 1.6613 - 2.256 0.576 - 375.5 1 1 0 0.0026 13 0 0 0 - - - - - 5.3826 0.9998 221125_WJC_METTL3_EV_vs_WT_F02.22969.22969.2 0.000657 18-Oct R.EC[160.03]LNLWGYER[166.11].V sp|Q86U44|MTA70_HUMAN 1 1348.6109 -1 21749 22969 2 1348.609147 675.3127 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 4.53 3767.6 - 4.16E+07 - - - -1.3303 - 1.881 0.532 - 468.4 1 2 0 -0.0018 10 0 0 0 0.00E+00 0.00E+00 - - - 4.7333 1 221125_WJC_METTL3_EV_vs_WT_F02.22972.22972.2 8.93E-09 14/22 K.STQFEYAWC[160.03]LVR.S sp|Q9Y3D6|FIS1_HUMAN 1 1558.7238 1.26 21752 22972 2 1558.722604 780.3692 Mitochondrial fission 1 protein OS=Homo sapiens OX=9606 GN=FIS1 PE=1 SV=2 5.72 3767.7 - 8.72E+06 - - - -0.7987 - 2.532 0.635 - 1005.6 1 2 0 -0.0012 12 0 0 0 2.28E+08 1.81E+08 - - - 6.1751 0.9999 221125_WJC_METTL3_EV_vs_WT_F02.22976.22976.2 5.65E-09 14/30 R.ESVLTATSILNNPIVK.A "sp|Q5BKZ1|ZN326_HUMAN,tr|A0A0A0MRN4|A0A0A0MRN4_HUMAN" 2 1697.9564 1.6 21756 22976 2 1697.95548 849.9855 DBIRD complex subunit ZNF326 OS=Homo sapiens OX=9606 GN=ZNF326 PE=1 SV=2 6.1 3768 - 2.71E+06 - - - -0.513 - 3.145 0.495 - 762.1 1 2 0 -0.0009 16 0 0 0 9.84E+07 6.15E+07 - - - 5.5138 1 221125_WJC_METTL3_EV_vs_WT_F02.22977.22977.2 3.38E-09 20/30 R.ESVLTATSILNNPIVK[136.11].A "sp|Q5BKZ1|ZN326_HUMAN,tr|A0A0A0MRN4|A0A0A0MRN4_HUMAN" 2 1705.9706 1.6 21757 22977 2 1705.965944 853.9926 DBIRD complex subunit ZNF326 OS=Homo sapiens OX=9606 GN=ZNF326 PE=1 SV=2 6.1 3768.1 - 2.35E+06 - - - -2.7005 - 3.473 0.565 - 1505.4 1 2 0 -0.0046 16 0 0 0 9.84E+07 6.15E+07 - - - 6.2736 1 221125_WJC_METTL3_EV_vs_WT_F02.22981.22981.2 6.60E-08 17/28 R.GFQFVSSSLPDIC[160.03]YR.C "sp|P62633|CNBP_HUMAN,tr|D6RAT4|D6RAT4_HUMAN" 2 1774.8349 0.48 21761 22981 2 1774.832564 888.4247 CCHC-type zinc finger nucleic acid binding protein OS=Homo sapiens OX=9606 GN=CNBP PE=1 SV=1 5.83 3768.7 - 1.07E+06 - - - -1.2914 - 3.066 0.591 - 1004.9 1 2 0 -0.0023 15 0 0 0 1.50E+07 3.10E+07 - - - 6.1599 1 221125_WJC_METTL3_EV_vs_WT_F02.22982.22982.2 4.56E-10 14/34 R.LFSASEFEDPLVGEDTER[166.11].A "sp|P37268|FDFT_HUMAN,tr|A0A1W2PQ47|A0A1W2PQ47_HUMAN,tr|E9PNM1|E9PNM1_HUMAN" 3 2049.9407 1.16 21762 22982 2 2049.939388 1025.9776 Squalene synthase OS=Homo sapiens OX=9606 GN=FDFT1 PE=1 SV=1 3.77 3768.8 - 835296 - - - -0.6161 - 3.108 0.644 - 416.7 1 2 0 -0.0013 18 0 0 0 5.21E+06 4.49E+06 - - - 6.5851 1 221125_WJC_METTL3_EV_vs_WT_F02.22985.22985.3 3.68E-06 15/68 R.IGPYQPNVPVGIDYVIPK.T "sp|P43243|MATR3_HUMAN,tr|B3KM87|B3KM87_HUMAN,tr|A8MXP9|A8MXP9_HUMAN,tr|A0A0R4J2E8|A0A0R4J2E8_HUMAN" 4 1968.072 1.46 21763 22985 3 1968.071775 657.0313 Matrin-3 OS=Homo sapiens OX=9606 GN=MATR3 PE=1 SV=2 5.83 3769.2 - 2.73E+07 - - - -0.1397 - 2.716 0.517 - 206.5 1 2 0 -0.0003 18 0 0 0 4.51E+09 3.10E+09 - - - 6.792 1 221125_WJC_METTL3_EV_vs_WT_F02.22988.22988.2 4.91E-10 28-Dec K.GVYPDLLATSGDYLR[166.11].V sp|P61962|DCAF7_HUMAN 1 1648.8336 1.33 21766 22988 2 1648.831891 825.4241 DDB1- and CUL4-associated factor 7 OS=Homo sapiens OX=9606 GN=DCAF7 PE=1 SV=1 4.21 3769.4 - 4.63E+06 - - - -1.0407 - 2.428 0.628 - 352.4 1 2 0 -0.0017 15 0 0 0 5.54E+07 4.15E+07 - - - 5.8598 1 221125_WJC_METTL3_EV_vs_WT_F02.22991.22991.3 2.81E-07 15/44 K.STQFEYAWC[160.03]LVR.S sp|Q9Y3D6|FIS1_HUMAN 1 1558.7238 1.26 21769 22991 3 1558.724032 520.5819 Mitochondrial fission 1 protein OS=Homo sapiens OX=9606 GN=FIS1 PE=1 SV=2 5.72 3769.6 - 2.48E+06 - - - 0.1174 - 2.792 0.61 - 333.1 1 2 0 0.0002 12 0 0 0 2.54E+07 2.02E+07 - - - 8.1869 0.9688 221125_WJC_METTL3_EV_vs_WT_F02.22992.22992.3 0.00805 14/64 L.QLVEPFGVISNHLILNK[136.11].L "sp|P43243|MATR3_HUMAN,tr|D6RE02|D6RE02_HUMAN,tr|B3KM87|B3KM87_HUMAN,tr|A8MXP9|A8MXP9_HUMAN,tr|D6R991|D6R991_HUMAN,tr|D6RBK5|D6RBK5_HUMAN,tr|A0A0R4J2E8|A0A0R4J2E8_HUMAN,tr|D6RIA2|D6RIA2_HUMAN,tr|H0Y8T4|H0Y8T4_HUMAN,tr|D6REM6|D6REM6_HUMAN,tr|D6RBI2|D6RBI2_HUMAN" 11 1928.0975 1.45 21770 22992 3 1928.096954 643.7064 Matrin-3 OS=Homo sapiens OX=9606 GN=MATR3 PE=1 SV=2 6.75 3769.6 - 5.74E+06 - - - -0.2744 - 2.478 0.303 - 260.9 1 1 0 -0.0005 17 0 0 0 9.25E+07 6.36E+07 - - - 4.2105 0.9999 221125_WJC_METTL3_EV_vs_WT_F02.22993.22993.2 2.32E-07 17/30 K.IITLEEGDIILTGTPK[136.11].G sp|Q6P587|FAHD1_HUMAN 1 1719.975 1.05 21771 22993 2 1719.97341 860.9948 "Acylpyruvase FAHD1, mitochondrial OS=Homo sapiens OX=9606 GN=FAHD1 PE=1 SV=2" 4.14 3769.7 - 1.91E+06 - - - -0.9058 - 3.2 0.515 - 767.2 1 2 0 -0.0016 16 0 0 0 9.05E+06 8.65E+06 - - - 5.704 0.9909 221125_WJC_METTL3_EV_vs_WT_F02.22994.22994.3 0.000883 13/52 Q.EMIGSVEEQLAQLR.C sp|P02533|K1C14_HUMAN 1 1601.8083 27.06 21772 22994 3 1601.809026 534.9434 "Keratin, type I cytoskeletal 14 OS=Homo sapiens OX=9606 GN=KRT14 PE=1 SV=4" 4.25 3769.9 - 1.39E+06 - - - 0.4489 - 2.217 0.419 - 168 1 1 0 0.0007 14 0 0 0 1.14E+07 4.22E+05 - - - 5.327 0.9999 221125_WJC_METTL3_EV_vs_WT_F02.22996.22996.3 4.94E-06 15/44 K.TVTAMDVVYALK[136.11].R sp|P62805|H4_HUMAN 1 1317.7094 1.63 21774 22996 3 1317.712469 440.2437 Histone H4 OS=Homo sapiens OX=9606 GN=H4C1 PE=1 SV=2 5.5 3770.1 - 1.05E+06 - - - 2.348 - 2.693 0.426 - 409 1 2 0 0.0031 12 0 0 0 9.13E+06 5.58E+06 - - - 6.0346 0.9999 221125_WJC_METTL3_EV_vs_WT_F02.22998.22998.3 1.08E-05 14/60 K.IITLEEGDIILTGTPK[136.11].G sp|Q6P587|FAHD1_HUMAN 1 1719.975 1.36 21776 22998 3 1719.972373 574.3323 "Acylpyruvase FAHD1, mitochondrial OS=Homo sapiens OX=9606 GN=FAHD1 PE=1 SV=2" 4.14 3770.4 - 724853 - - - -1.5087 - 2.313 0.42 - 225.3 1 2 0 -0.0026 16 0 0 0 6.98E+06 5.13E+06 - - - 5.3735 1 221125_WJC_METTL3_EV_vs_WT_F02.23002.23002.2 5.44E-13 19/36 R.YEGILYTIDTENSTVALAK.V "sp|Q8ND56|LS14A_HUMAN,tr|I3L4Q1|I3L4Q1_HUMAN,tr|A0A140TA76|A0A140TA76_HUMAN,tr|K7EMZ9|K7EMZ9_HUMAN" 4 2100.0627 1.27 21779 23002 2 2100.059688 1051.0386 Protein LSM14 homolog A OS=Homo sapiens OX=9606 GN=LSM14A PE=1 SV=3 4.14 3770.9 - 2.08E+06 - - - -1.4185 - 3.24 0.676 - 915.5 1 2 0 -0.003 19 0 0 0 6.71E+07 5.29E+07 - - - 6.9232 1 221125_WJC_METTL3_EV_vs_WT_F02.23004.23004.3 1.80E-08 16/68 R.IGPYQPNVPVGIDYVIPK[136.11].T "sp|P43243|MATR3_HUMAN,tr|B3KM87|B3KM87_HUMAN,tr|A8MXP9|A8MXP9_HUMAN,tr|A0A0R4J2E8|A0A0R4J2E8_HUMAN" 4 1976.0863 1.45 21780 23004 3 1976.085246 659.7027 Matrin-3 OS=Homo sapiens OX=9606 GN=MATR3 PE=1 SV=2 5.83 3771.1 - 6.24E+07 - - - -0.5081 - 2.935 0.522 - 300.3 1 2 0 -0.001 18 0 0 0 4.51E+09 3.10E+09 - - - 7.0406 1 221125_WJC_METTL3_EV_vs_WT_F02.23005.23005.2 3.55E-07 14/26 R.VGNLGLATSFFNER.N "sp|O00571|DDX3X_HUMAN,tr|A0A2R8YFR4|A0A2R8YFR4_HUMAN,tr|A0A2R8YCW1|A0A2R8YCW1_HUMAN,tr|A0A2R8YDT5|A0A2R8YDT5_HUMAN,tr|A0A2R8Y645|A0A2R8Y645_HUMAN,tr|A0A2R8YF78|A0A2R8YF78_HUMAN,tr|A0A0D9SFB3|A0A0D9SFB3_HUMAN,tr|A0A2R8YFS5|A0A2R8YFS5_HUMAN,tr|A0A0D9SF53|A0A0D9SF53_HUMAN,tr|A0A087WVZ1|A0A087WVZ1_HUMAN,tr|A0A0J9YVQ7|A0A0J9YVQ7_HUMAN,tr|A0A2R8Y5G6|A0A2R8Y5G6_HUMAN,tr|A0A2R8Y7T2|A0A2R8Y7T2_HUMAN,tr|A0A0D9SG12|A0A0D9SG12_HUMAN,tr|F6S8Q4|F6S8Q4_HUMAN,tr|A0A2U3TZJ9|A0A2U3TZJ9_HUMAN,tr|A0A2R8Y4A4|A0A2R8Y4A4_HUMAN" 17 1523.7732 1.19 21781 23005 2 1523.772939 762.8939 ATP-dependent RNA helicase DDX3X OS=Homo sapiens OX=9606 GN=DDX3X PE=1 SV=3 5.97 3771.2 - 3.35E+07 - - - -0.1988 - 2.682 0.655 - 624.9 1 2 0 -0.0003 14 0 0 0 4.05E+08 3.41E+08 - - - 6.3545 0.9792 221125_WJC_METTL3_EV_vs_WT_F02.23008.23008.3 0.138 Jul-60 R.ESVLTATSILNNPIVK.A "sp|Q5BKZ1|ZN326_HUMAN,tr|A0A0A0MRN4|A0A0A0MRN4_HUMAN" 2 1697.9564 1.71 21784 23008 3 1697.955838 566.9927 DBIRD complex subunit ZNF326 OS=Homo sapiens OX=9606 GN=ZNF326 PE=1 SV=2 6.1 3771.3 - 5.15E+06 - - - -0.3021 - 1.413 0.194 - 15.1 3 2 0 -0.0005 16 0 0 0 4.02E+07 2.35E+07 - - - 1.369 1 221125_WJC_METTL3_EV_vs_WT_F02.23009.23009.3 5.97E-05 16/52 R.VGNLGLATSFFNER[166.11].N "sp|O00571|DDX3X_HUMAN,tr|A0A2R8YFR4|A0A2R8YFR4_HUMAN,tr|A0A2R8YCW1|A0A2R8YCW1_HUMAN,tr|A0A2R8YDT5|A0A2R8YDT5_HUMAN,tr|A0A2R8Y645|A0A2R8Y645_HUMAN,tr|A0A2R8YF78|A0A2R8YF78_HUMAN,tr|A0A0D9SFB3|A0A0D9SFB3_HUMAN,tr|A0A2R8YFS5|A0A2R8YFS5_HUMAN,tr|A0A0D9SF53|A0A0D9SF53_HUMAN,tr|A0A087WVZ1|A0A087WVZ1_HUMAN,tr|A0A0J9YVQ7|A0A0J9YVQ7_HUMAN,tr|A0A2R8Y5G6|A0A2R8Y5G6_HUMAN,tr|A0A2R8Y7T2|A0A2R8Y7T2_HUMAN,tr|A0A0D9SG12|A0A0D9SG12_HUMAN,tr|F6S8Q4|F6S8Q4_HUMAN,tr|A0A2U3TZJ9|A0A2U3TZJ9_HUMAN,tr|A0A2R8Y4A4|A0A2R8Y4A4_HUMAN" 17 1533.7815 1.3 21785 23009 3 1533.781405 512.2678 ATP-dependent RNA helicase DDX3X OS=Homo sapiens OX=9606 GN=DDX3X PE=1 SV=3 5.97 3771.4 - 4.71E+06 - - - -0.0698 - 2.661 0.474 - 323.9 1 2 0 -0.0001 14 0 0 0 4.41E+07 3.38E+07 - - - 6.4255 1 221125_WJC_METTL3_EV_vs_WT_F02.23010.23010.3 5.87E-06 Dec-52 R.ILVQQFEVQLQQYR.Q "sp|Q9BVL2|NUP58_HUMAN,tr|H7BYF2|H7BYF2_HUMAN,tr|Q5JRG1|Q5JRG1_HUMAN" 3 1790.9679 3.46 21786 23010 3 1790.965378 597.9966 Nucleoporin p58\p45 OS=Homo sapiens OX=9606 GN=NUP58 PE=1 SV=1 6 3771.4 - 4.07E+06 - - - -1.4188 - 2.812 0.509 - 242.7 1 2 0 -0.0025 14 0 0 0 2.20E+07 6.38E+06 - - - 6.9618 0.9997 221125_WJC_METTL3_EV_vs_WT_F02.23011.23011.2 0.000244 24-Dec K.ISFLENNLEQLTK.V "sp|Q12840|KIF5A_HUMAN,sp|O60282|KIF5C_HUMAN,sp|P33176|KINH_HUMAN,tr|J3KNA1|J3KNA1_HUMAN,tr|A0A6Q8PEZ8|A0A6Q8PEZ8_HUMAN,tr|A0A0G2JMZ6|A0A0G2JMZ6_HUMAN,tr|A0A6Q8PGJ3|A0A6Q8PGJ3_HUMAN,tr|A0A7I2YQQ7|A0A7I2YQQ7_HUMAN,tr|A0A7I2V581|A0A7I2V581_HUMAN,tr|A0A7I2V3N5|A0A7I2V3N5_HUMAN,tr|A0A7I2V492|A0A7I2V492_HUMAN,tr|A0A6Q8PGN1|A0A6Q8PGN1_HUMAN,tr|A0A7I2V352|A0A7I2V352_HUMAN,tr|A0A7I2V4K6|A0A7I2V4K6_HUMAN,tr|A0A6Q8PGT2|A0A6Q8PGT2_HUMAN" 15 1547.8195 1.25 21787 23011 2 1547.822412 774.917 Kinesin heavy chain isoform 5A OS=Homo sapiens OX=9606 GN=KIF5A PE=1 SV=2 4.53 3771.5 - 3.76E+06 - - - 1.8665 - 2.662 0.435 - 366.1 1 2 0 0.0029 13 0 0 0 3.02E+07 2.42E+07 - - - 4.7658 0.9999 221125_WJC_METTL3_EV_vs_WT_F02.23013.23013.3 8.89E-05 15/64 R.LAALPENPPAIDWAYYK[136.11].A "sp|O75947|ATP5H_HUMAN,tr|F5H608|F5H608_HUMAN" 2 1938.9971 1.28 21789 23013 3 1938.995614 647.3396 "ATP synthase subunit d, mitochondrial OS=Homo sapiens OX=9606 GN=ATP5PD PE=1 SV=3" 4.37 3771.6 - 2.53E+06 - - - -0.7664 - 2.986 0.378 - 333.2 1 2 0 -0.0015 17 0 0 0 4.93E+07 3.85E+07 - - - 5.5175 1 221125_WJC_METTL3_EV_vs_WT_F02.23014.23014.3 2.01E-06 Nov-44 K.STQFEYAWC[160.03]LVR[166.11].S sp|Q9Y3D6|FIS1_HUMAN 1 1568.7321 1.26 21790 23014 3 1568.731506 523.918 Mitochondrial fission 1 protein OS=Homo sapiens OX=9606 GN=FIS1 PE=1 SV=2 5.72 3771.7 - 2.38E+06 - - - -0.3908 - 1.801 0.589 - 169.5 1 2 0 -0.0006 12 0 0 0 2.54E+07 2.02E+07 - - - 6.7374 1 221125_WJC_METTL3_EV_vs_WT_F02.23015.23015.3 3.63E-06 15/72 R.YEGILYTIDTENSTVALAK[136.11].V "sp|Q8ND56|LS14A_HUMAN,tr|I3L4Q1|I3L4Q1_HUMAN,tr|A0A140TA76|A0A140TA76_HUMAN,tr|K7EMZ9|K7EMZ9_HUMAN" 4 2108.0769 0.98 21791 23015 3 2108.075398 703.6996 Protein LSM14 homolog A OS=Homo sapiens OX=9606 GN=LSM14A PE=1 SV=3 4.14 3771.7 - 2.25E+06 - - - -0.6968 - 2.623 0.464 - 157.1 1 2 0 -0.0015 19 0 0 0 5.98E+07 6.12E+07 - - - 6.0819 0.9999 221125_WJC_METTL3_EV_vs_WT_F02.23016.23016.3 3.44E-06 Dec-52 R.ILVQQFEVQLQQYR[166.11].Q "sp|Q9BVL2|NUP58_HUMAN,tr|H7BYF2|H7BYF2_HUMAN,tr|Q5JRG1|Q5JRG1_HUMAN" 3 1800.9762 3.34 21792 23016 3 1800.973263 601.3327 Nucleoporin p58\p45 OS=Homo sapiens OX=9606 GN=NUP58 PE=1 SV=1 6 3771.8 - 1.60E+06 - - - -1.6247 - 2.455 0.472 - 278.8 1 2 0 -0.0029 14 0 0 0 2.22E+07 6.65E+06 - - - 6.1883 1 221125_WJC_METTL3_EV_vs_WT_F02.23017.23017.2 7.80E-09 14/26 R.ILVQQFEVQLQQYR.Q "sp|Q9BVL2|NUP58_HUMAN,tr|H7BYF2|H7BYF2_HUMAN,tr|Q5JRG1|Q5JRG1_HUMAN" 3 1790.9679 3.05 21793 23017 2 1790.968306 896.4912 Nucleoporin p58\p45 OS=Homo sapiens OX=9606 GN=NUP58 PE=1 SV=1 6 3771.9 - 1.58E+06 - - - 0.2161 - 3.141 0.616 - 677.8 1 2 0 0.0004 14 0 0 0 1.13E+07 3.69E+06 - - - 6.4628 0.9998 221125_WJC_METTL3_EV_vs_WT_F02.23018.23018.3 0.000106 18/56 K.K[136.11]EDLELIMTEMEISR[166.11].A sp|Q9NX55|HYPK_HUMAN 1 1853.9234 1.86 21794 23018 3 1853.918793 618.9817 Huntingtin-interacting protein K OS=Homo sapiens OX=9606 GN=HYPK PE=1 SV=2 4.25 3772.1 - 1.07E+06 - - - -2.4618 - 2.643 0.39 - 335.5 1 2 0 -0.0046 15 0 0 0 8.82E+06 4.75E+06 - - - 5.4229 1 221125_WJC_METTL3_EV_vs_WT_F02.23019.23019.2 3.78E-06 30-Dec K.GQFLDFSTMQATELGK[136.11].L sp|P48634|PRC2A_HUMAN 1 1779.8593 1.97 21795 23019 2 1779.846422 890.9369 Protein PRRC2A OS=Homo sapiens OX=9606 GN=PRRC2A PE=1 SV=3 4.37 3772.2 - 1.07E+06 - - - -7.2275 - 2.938 0.597 - 353.6 1 2 0 -0.0129 16 0 0 0 1.35E+07 6.84E+06 - - - 6.096 0.996 221125_WJC_METTL3_EV_vs_WT_F02.23020.23020.2 7.30E-07 24-Nov K.YVDIGVLASDLQR[166.11].V "sp|O15381|NVL_HUMAN,tr|E9PH71|E9PH71_HUMAN,tr|F8WF01|F8WF01_HUMAN,tr|E7EWK7|E7EWK7_HUMAN,tr|E9PGD8|E9PGD8_HUMAN" 5 1457.7754 2.4 21796 23020 2 1457.766789 729.895 Nuclear valosin-containing protein-like OS=Homo sapiens OX=9606 GN=NVL PE=1 SV=1 4.21 3772.3 - 1.03E+06 - - - -5.8823 - 2.525 0.483 - 333.7 1 2 0 -0.0086 13 0 0 0 1.63E+07 6.78E+06 - - - 4.983 0.9991 221125_WJC_METTL3_EV_vs_WT_F02.23021.23021.3 0.00457 Nov-40 K.YK[136.11]ETDLLILFK[136.11].D sp|P05455|LA_HUMAN 1 1397.8141 0.93 21797 23021 3 1397.81351 466.9453 Lupus La protein OS=Homo sapiens OX=9606 GN=SSB PE=1 SV=2 6.07 3772.4 - 706125 - - - -0.4249 - 2.145 0.347 - 231.7 1 2 1 -0.0006 11 0 0 0 2.96E+07 3.19E+07 - - - 4.5765 1 221125_WJC_METTL3_EV_vs_WT_F02.23024.23024.2 1.07E-13 19/36 R.YEGILYTIDTENSTVALAK[136.11].V "sp|Q8ND56|LS14A_HUMAN,tr|I3L4Q1|I3L4Q1_HUMAN,tr|A0A140TA76|A0A140TA76_HUMAN,tr|K7EMZ9|K7EMZ9_HUMAN" 4 2108.0769 1.22 21799 23024 2 2108.079861 1055.0457 Protein LSM14 homolog A OS=Homo sapiens OX=9606 GN=LSM14A PE=1 SV=3 4.14 3772.8 - 1.15E+06 - - - 1.4203 - 3.846 0.701 - 928.5 1 2 0 0.003 19 0 0 0 6.35E+07 5.22E+07 - - - 7.5294 0.9999 221125_WJC_METTL3_EV_vs_WT_F02.23025.23025.2 3.46E-07 26-Nov R.VGNLGLATSFFNER[166.11].N "sp|O00571|DDX3X_HUMAN,tr|A0A2R8YFR4|A0A2R8YFR4_HUMAN,tr|A0A2R8YCW1|A0A2R8YCW1_HUMAN,tr|A0A2R8YDT5|A0A2R8YDT5_HUMAN,tr|A0A2R8Y645|A0A2R8Y645_HUMAN,tr|A0A2R8YF78|A0A2R8YF78_HUMAN,tr|A0A0D9SFB3|A0A0D9SFB3_HUMAN,tr|A0A2R8YFS5|A0A2R8YFS5_HUMAN,tr|A0A0D9SF53|A0A0D9SF53_HUMAN,tr|A0A087WVZ1|A0A087WVZ1_HUMAN,tr|A0A0J9YVQ7|A0A0J9YVQ7_HUMAN,tr|A0A2R8Y5G6|A0A2R8Y5G6_HUMAN,tr|A0A2R8Y7T2|A0A2R8Y7T2_HUMAN,tr|A0A0D9SG12|A0A0D9SG12_HUMAN,tr|F6S8Q4|F6S8Q4_HUMAN,tr|A0A2U3TZJ9|A0A2U3TZJ9_HUMAN,tr|A0A2R8Y4A4|A0A2R8Y4A4_HUMAN" 17 1533.7815 1.19 21800 23025 2 1533.780875 767.898 ATP-dependent RNA helicase DDX3X OS=Homo sapiens OX=9606 GN=DDX3X PE=1 SV=3 5.97 3772.8 - 3.68E+07 - - - -0.4153 - 2.285 0.56 - 324.2 1 2 0 -0.0006 14 0 0 0 4.05E+08 3.41E+08 - - - 5.2507 0.9999 221125_WJC_METTL3_EV_vs_WT_F02.23026.23026.3 0.0083 13/56 R.VISGVLQLGNIVFK[136.11]K[136.11].E sp|P35579|MYH9_HUMAN 1 1630.0153 0.79 21801 23026 3 1630.01312 544.3457 Myosin-9 OS=Homo sapiens OX=9606 GN=MYH9 PE=1 SV=4 10 3772.9 - 5.03E+06 - - - -1.3153 - 2.462 0.443 - 170.3 1 2 0 -0.0021 15 0 0 0 3.22E+07 4.08E+07 - - - 5.8294 0.9997 221125_WJC_METTL3_EV_vs_WT_F02.23029.23029.3 0.0769 Dec-60 R.ESVLTATSILNNPIVK[136.11].A "sp|Q5BKZ1|ZN326_HUMAN,tr|A0A0A0MRN4|A0A0A0MRN4_HUMAN" 2 1705.9706 1.71 21804 23029 3 1705.968927 569.6641 DBIRD complex subunit ZNF326 OS=Homo sapiens OX=9606 GN=ZNF326 PE=1 SV=2 6.1 3773.1 - 2.74E+06 - - - -0.952 - 2.324 0.324 - 149.7 1 2 0 -0.0016 16 0 0 0 4.02E+07 2.35E+07 - - - 4.3156 0.9932 221125_WJC_METTL3_EV_vs_WT_F02.23030.23030.3 0.000133 13/40 K.YKETDLLILFK.D sp|P05455|LA_HUMAN 1 1381.7857 0.93 21805 23030 3 1381.785078 461.6025 Lupus La protein OS=Homo sapiens OX=9606 GN=SSB PE=1 SV=2 6.07 3773.1 - 2.08E+06 - - - -0.453 - 2.173 0.205 - 212.6 1 2 1 -0.0006 11 0 0 0 2.96E+07 3.19E+07 - - - 3.0302 1 221125_WJC_METTL3_EV_vs_WT_F02.23032.23032.2 6.98E-07 13/30 K.GQFLDFSTMQATELGK.L sp|P48634|PRC2A_HUMAN 1 1771.8451 1.97 21807 23032 2 1771.84991 886.9298 Protein PRRC2A OS=Homo sapiens OX=9606 GN=PRRC2A PE=1 SV=3 4.37 3773.4 - 1.37E+06 - - - 2.7226 - 2.888 0.597 - 408.1 1 2 0 0.0048 16 0 0 0 1.35E+07 6.84E+06 - - - 6.0564 0.9942 221125_WJC_METTL3_EV_vs_WT_F02.23033.23033.2 0.00249 30-Nov K.IITLEEGDIILTGTPK.G sp|Q6P587|FAHD1_HUMAN 1 1711.9608 1.05 21808 23033 2 1711.966774 856.9877 "Acylpyruvase FAHD1, mitochondrial OS=Homo sapiens OX=9606 GN=FAHD1 PE=1 SV=2" 4.14 3773.5 - 1.05E+06 - - - 3.5083 - 2.022 0.232 - 204.2 1 2 0 0.006 16 0 0 0 9.05E+06 8.65E+06 - - - 2.4837 0.8968 221125_WJC_METTL3_EV_vs_WT_F02.23036.23036.2 2.79 26-Jun R.GIPNMLLSEEETES.- sp|Q9UI30|TR112_HUMAN 1 1547.7025 - 21809 23036 2 1547.701021 774.8585 Multifunctional methyltransferase subunit TRM112-like protein OS=Homo sapiens OX=9606 GN=TRMT112 PE=1 SV=1 3.58 3773.9 - 8.14E+06 - - - -0.9582 - 0.921 0.076 - 55.1 3 2 0 -0.0015 14 0 0 0 - - - - - -0.8178 1 221125_WJC_METTL3_EV_vs_WT_F02.23037.23037.2 0.00462 14/24 K.ILESSQTLLSVLK.R "sp|O43805|SSNA1_HUMAN,tr|A0A087WV26|A0A087WV26_HUMAN" 2 1429.8392 2.3 21810 23037 2 1429.838856 715.9269 Sjoegren syndrome nuclear autoantigen 1 OS=Homo sapiens OX=9606 GN=SSNA1 PE=1 SV=2 6 3774 - 1.95E+06 - - - -0.2378 - 2.84 0.569 - 530.5 1 2 0 -0.0003 13 0 0 0 5.20E+07 2.26E+07 - - - 5.9225 0.9991 221125_WJC_METTL3_EV_vs_WT_F02.23039.23039.3 0.000733 Dec-32 R.DLLQFFKPR.Q "sp|Q93009|UBP7_HUMAN,tr|A0A669KBL1|A0A669KBL1_HUMAN,tr|H3BND8|H3BND8_HUMAN" 3 1162.6499 0.98 21812 23039 3 1162.648427 388.5572 Ubiquitin carboxyl-terminal hydrolase 7 OS=Homo sapiens OX=9606 GN=USP7 PE=1 SV=2 8.75 3774.2 - 1.02E+06 - - - -1.2489 - 1.846 0.28 - 239.7 1 2 0 -0.0015 9 0 0 0 2.71E+07 2.75E+07 - - - 3.5088 0.9998 221125_WJC_METTL3_EV_vs_WT_F02.23042.23042.2 4.26E-07 22-Sep R.SDYLNTFEFMDK.L sp|O75874|IDHC_HUMAN 1 1508.6493 2.94 21815 23042 2 1508.64581 755.3319 Isocitrate dehydrogenase [NADP] cytoplasmic OS=Homo sapiens OX=9606 GN=IDH1 PE=1 SV=2 4.03 3774.6 - 840073 - - - -2.3445 - 2.093 0.619 - 155 1 2 0 -0.0035 12 0 0 0 7.20E+06 2.45E+06 - - - 5.5552 0.9993 221125_WJC_METTL3_EV_vs_WT_F02.23045.23045.2 0.000111 18-Nov R.AFDLFNPNFK[136.11].S "sp|Q9Y3D9|RT23_HUMAN,tr|J3QLR8|J3QLR8_HUMAN" 2 1219.6117 1.42 21816 23045 2 1219.611655 610.8131 "28S ribosomal protein S23, mitochondrial OS=Homo sapiens OX=9606 GN=MRPS23 PE=1 SV=2" 5.88 3774.9 - 2.52E+06 - - - -0.0443 - 1.77 0.284 - 309.4 1 2 0 -0.0001 10 0 0 0 4.84E+07 3.41E+07 - - - 2.7324 1 221125_WJC_METTL3_EV_vs_WT_F02.23048.23048.2 7.17E-07 16/30 K.MFIGGLSWQTTQEGLR.E sp|O43347|MSI1H_HUMAN 1 1822.9036 0.95 21819 23048 2 1822.904918 912.4591 RNA-binding protein Musashi homolog 1 OS=Homo sapiens OX=9606 GN=MSI1 PE=1 SV=1 5.75 3775.2 - 2.38E+06 - - - 0.7208 - 2.965 0.554 - 769.9 1 2 0 0.0013 16 0 0 0 1.19E+08 1.25E+08 - - - 5.8046 0.9986 221125_WJC_METTL3_EV_vs_WT_F02.23049.23049.3 0.0253 Dec-32 R.DLLQFFK[136.11]PR[166.11].Q "sp|Q93009|UBP7_HUMAN,tr|A0A669KBL1|A0A669KBL1_HUMAN,tr|H3BND8|H3BND8_HUMAN" 3 1180.6723 0.98 21820 23049 3 1180.671575 394.5647 Ubiquitin carboxyl-terminal hydrolase 7 OS=Homo sapiens OX=9606 GN=USP7 PE=1 SV=2 8.75 3775.3 - 2.19E+06 - - - -0.6556 - 1.888 0.234 - 243 1 2 0 -0.0008 9 0 0 0 2.71E+07 2.75E+07 - - - 3.064 1 221125_WJC_METTL3_EV_vs_WT_F02.23050.23050.2 1.23E-09 16/24 R.DVLDFYNVPIQDR.S sp|Q8N5N7|RM50_HUMAN 1 1592.7835 3.58 21821 23050 2 1592.781385 797.399 "39S ribosomal protein L50, mitochondrial OS=Homo sapiens OX=9606 GN=MRPL50 PE=1 SV=2" 3.93 3775.4 - 1.62E+06 - - - -1.3103 - 3.101 0.665 - 912.1 1 2 0 -0.0021 13 0 0 0 2.15E+07 6.00E+06 - - - 6.8566 0.9997 221125_WJC_METTL3_EV_vs_WT_F02.23052.23052.2 9.18E-05 22-Nov K.LVGQSIIAYLQK[136.11].K "sp|P53621|COPA_HUMAN,tr|A0A3B3IU89|A0A3B3IU89_HUMAN,tr|A0A3B3IT15|A0A3B3IT15_HUMAN" 3 1339.7955 0.11 21823 23052 2 1339.793706 670.905 Coatomer subunit alpha OS=Homo sapiens OX=9606 GN=COPA PE=1 SV=2 8.59 3775.6 - 1.45E+06 - - - -1.3293 - 1.894 0.453 - 334.6 1 2 0 -0.0018 12 0 0 0 1.86E+06 1.76E+07 - - - 4.0668 0.9983 221125_WJC_METTL3_EV_vs_WT_F02.23054.23054.3 0.0333 17/76 R.YGAASGVVPGSLWPSPEQLR.E sp|Q8TAE8|G45IP_HUMAN 1 2070.0534 2.5 21825 23054 3 2070.050633 691.0251 Growth arrest and DNA damage-inducible proteins-interacting protein 1 OS=Homo sapiens OX=9606 GN=GADD45GIP1 PE=1 SV=1 6 3775.8 - 1.20E+06 - - - -1.356 - 2.131 0.241 - 181.5 1 2 0 -0.0028 20 0 0 0 3.60E+07 1.44E+07 - - - 3.0616 1 221125_WJC_METTL3_EV_vs_WT_F02.23055.23055.2 6.68E-09 15/26 K.DPIVNVWYSVNGER.L "sp|Q13347|EIF3I_HUMAN,tr|A0A7I2V613|A0A7I2V613_HUMAN,tr|A0A7I2V3N2|A0A7I2V3N2_HUMAN,tr|A0A7I2YQU2|A0A7I2YQU2_HUMAN,tr|A0A7I2YQX4|A0A7I2YQX4_HUMAN,tr|A0A7I2YQI6|A0A7I2YQI6_HUMAN,tr|A0A7I2YQF8|A0A7I2YQF8_HUMAN,tr|Q5TFK1|Q5TFK1_HUMAN,tr|A0A7I2V3U3|A0A7I2V3U3_HUMAN,tr|A0A7I2V607|A0A7I2V607_HUMAN,tr|A0A7I2V640|A0A7I2V640_HUMAN,tr|A0A7P0MRT9|A0A7P0MRT9_HUMAN,tr|A0A7I2V3T4|A0A7I2V3T4_HUMAN,tr|A0A7I2V3K6|A0A7I2V3K6_HUMAN,tr|A0A7I2V4S8|A0A7I2V4S8_HUMAN,tr|A0A7I2V5V8|A0A7I2V5V8_HUMAN,tr|A0A7I2V391|A0A7I2V391_HUMAN,tr|A0A7I2V5E4|A0A7I2V5E4_HUMAN,tr|A0A7I2YQN1|A0A7I2YQN1_HUMAN,tr|A0A7I2V2M3|A0A7I2V2M3_HUMAN,tr|A0A7I2YQP9|A0A7I2YQP9_HUMAN,tr|A0A7I2YQI2|A0A7I2YQI2_HUMAN,tr|A0A7I2V685|A0A7I2V685_HUMAN" 23 1646.8053 1.3 21826 23055 2 1646.812874 824.4099 Eukaryotic translation initiation factor 3 subunit I OS=Homo sapiens OX=9606 GN=EIF3I PE=1 SV=1 4.37 3776 - 1.00E+06 - - - 4.6174 - 2.778 0.621 - 843.9 1 2 0 0.0076 14 0 0 0 2.28E+07 1.76E+07 - - - 6.1893 0.9997 221125_WJC_METTL3_EV_vs_WT_F02.23058.23058.2 0.000352 16-Jun K.AAIDWFDGK.E "sp|P35637|FUS_HUMAN,sp|Q92804|RBP56_HUMAN,tr|H3BPE7|H3BPE7_HUMAN,tr|A0A075B7D9|A0A075B7D9_HUMAN" 4 1021.4869 0.92 21827 23058 2 1021.485749 511.7507 RNA-binding protein FUS OS=Homo sapiens OX=9606 GN=FUS PE=1 SV=1 4.21 3776.4 - 1.90E+07 - - - -1.1229 - 1.457 0.489 - 94.3 1 2 0 -0.0011 9 0 0 0 4.72E+07 5.15E+07 - - - 3.7413 0.9998 221125_WJC_METTL3_EV_vs_WT_F02.23073.23073.2 0.000346 18-Aug R.AFDLFNPNFK.S "sp|Q9Y3D9|RT23_HUMAN,tr|J3QLR8|J3QLR8_HUMAN" 2 1211.5975 1.42 21841 23073 2 1211.596615 606.806 "28S ribosomal protein S23, mitochondrial OS=Homo sapiens OX=9606 GN=MRPS23 PE=1 SV=2" 5.88 3777.6 - 4.75E+06 - - - -0.7379 - 1.905 0.451 - 161.7 1 2 0 -0.0009 10 0 0 0 4.84E+07 3.41E+07 - - - 4.1708 0.9999 221125_WJC_METTL3_EV_vs_WT_F02.23075.23075.2 1.31E-07 20-Nov K.SFFDNISSELK[136.11].T "sp|Q9BX40|LS14B_HUMAN,tr|Q5TBP9|Q5TBP9_HUMAN" 2 1293.6332 0.81 21843 23075 2 1293.632944 647.8239 Protein LSM14 homolog B OS=Homo sapiens OX=9606 GN=LSM14B PE=1 SV=1 4.37 3777.7 - 7.19E+06 - - - -0.2234 - 2.051 0.613 - 268.1 1 2 0 -0.0003 11 0 0 0 1.10E+08 1.36E+08 - - - 5.5118 1 221125_WJC_METTL3_EV_vs_WT_F02.23076.23076.2 3.49E-08 20-Nov K.SFFDNISSELK.T "sp|Q9BX40|LS14B_HUMAN,tr|Q5TBP9|Q5TBP9_HUMAN" 2 1285.619 0.81 21844 23076 2 1285.619182 643.8168 Protein LSM14 homolog B OS=Homo sapiens OX=9606 GN=LSM14B PE=1 SV=1 4.37 3777.8 - 5.42E+06 - - - 0.1159 - 2.164 0.629 - 288.5 1 2 0 0.0001 11 0 0 0 1.10E+08 1.36E+08 - - - 5.7751 0.9997 221125_WJC_METTL3_EV_vs_WT_F02.23077.23077.3 0.00217 Sep-60 K.MFIGGLSWQTTQEGLR.E sp|O43347|MSI1H_HUMAN 1 1822.9036 0.66 21845 23077 3 1822.902004 608.6418 RNA-binding protein Musashi homolog 1 OS=Homo sapiens OX=9606 GN=MSI1 PE=1 SV=1 5.75 3777.8 - 4.79E+06 - - - -0.8777 - 1.874 0.376 - 79.2 1 2 0 -0.0016 16 0 0 0 5.22E+07 7.87E+07 - - - 4.3431 1 221125_WJC_METTL3_EV_vs_WT_F02.23079.23079.3 9.31E-10 20/60 R.WVTYFNKPDIDAWELR.K "sp|P20674|COX5A_HUMAN,tr|H3BNX8|H3BNX8_HUMAN,tr|H3BRI0|H3BRI0_HUMAN" 3 2052.0105 1.46 21847 23079 3 2052.007406 685.0108 "Cytochrome c oxidase subunit 5A, mitochondrial OS=Homo sapiens OX=9606 GN=COX5A PE=1 SV=2" 4.56 3777.9 - 3.64E+06 - - - -1.5136 - 3.494 0.597 - 498.7 1 2 0 -0.0031 16 0 0 0 7.41E+07 5.08E+07 - - - 8.4051 1 221125_WJC_METTL3_EV_vs_WT_F02.23081.23081.3 4.05E-06 15/48 R.IDSLMDEISFLKK.V sp|P07196|NFL_HUMAN 1 1537.8062 2 21849 23081 3 1537.804944 513.6093 Neurofilament light polypeptide OS=Homo sapiens OX=9606 GN=NEFL PE=1 SV=3 4.56 3778.2 - 1.56E+06 - - - -0.805 - 2.681 0.482 - 326.5 1 2 0 -0.0012 13 0 0 0 1.63E+07 8.13E+06 - - - 6.5873 1 221125_WJC_METTL3_EV_vs_WT_F02.23082.23082.2 3.50E-09 16/28 K.VVSNFMDFDETGVLK[136.11].G "sp|Q9H0P0|5NT3A_HUMAN,tr|X6RM59|X6RM59_HUMAN" 2 1707.8269 1.43 21850 23082 2 1707.827997 854.9207 Cytosolic 5'-nucleotidase 3A OS=Homo sapiens OX=9606 GN=NT5C3A PE=1 SV=3 4.03 3778.3 - 1.21E+06 - - - 0.6283 - 2.672 0.657 - 749.3 1 2 0 0.0011 15 0 0 0 1.93E+07 1.34E+07 - - - 6.3096 0.9998 221125_WJC_METTL3_EV_vs_WT_F02.23083.23083.2 3.19E-07 16/32 R.ALIVVPYAEGVIPDEAK.A "sp|Q05519|SRS11_HUMAN,tr|Q5T760|Q5T760_HUMAN" 2 1782.9768 2.22 21851 23083 2 1782.979806 892.4957 Serine\arginine-rich splicing factor 11 OS=Homo sapiens OX=9606 GN=SRSF11 PE=1 SV=1 4.14 3778.5 - 977694 - - - 1.7129 - 2.795 0.556 - 506.3 1 2 0 0.0031 17 0 0 0 8.30E+07 3.74E+07 - - - 5.6736 1 221125_WJC_METTL3_EV_vs_WT_F02.23084.23084.3 3.73E-07 20/52 R.INLAEDVLAWEHER[166.11].F "sp|Q969V3|NCLN_HUMAN,tr|K7EMW4|K7EMW4_HUMAN,tr|K7ELZ9|K7ELZ9_HUMAN,tr|K7ENM2|K7ENM2_HUMAN,tr|K7EQ66|K7EQ66_HUMAN,tr|A0A0C4DGP7|A0A0C4DGP7_HUMAN" 6 1703.8507 1.22 21852 23084 3 1703.849719 568.9575 Nicalin OS=Homo sapiens OX=9606 GN=NCLN PE=1 SV=2 4.4 3778.6 - 820424 - - - -0.5488 - 3.152 0.536 - 378.2 1 2 0 -0.0009 14 0 0 0 1.04E+07 8.59E+06 - - - 7.5666 1 221125_WJC_METTL3_EV_vs_WT_F02.23085.23085.2 3.75E-08 24-Oct R.VFAEC[160.03]NDESFWFR[166.11].S "sp|Q9NX40|OCAD1_HUMAN,tr|D6RA54|D6RA54_HUMAN,tr|D6RBC5|D6RBC5_HUMAN,tr|D6R918|D6R918_HUMAN,tr|D6RF07|D6RF07_HUMAN,tr|D6RG39|D6RG39_HUMAN,tr|D6RDI5|D6RDI5_HUMAN,tr|D6RIT9|D6RIT9_HUMAN,tr|D6RC55|D6RC55_HUMAN" 9 1715.7278 2.4 21853 23085 2 1715.727545 858.8712 OCIA domain-containing protein 1 OS=Homo sapiens OX=9606 GN=OCIAD1 PE=1 SV=1 4.14 3778.7 - 559497 - - - -0.1265 - 2.599 0.666 - 394.5 1 2 0 -0.0002 13 0 0 0 8.10E+06 3.37E+06 - - - 6.4114 1 221125_WJC_METTL3_EV_vs_WT_F02.23089.23089.2 1.59E-06 24-Nov K.MLVLDEADEMLNK.G "sp|P38919|IF4A3_HUMAN,tr|I3L3H2|I3L3H2_HUMAN" 2 1519.7262 1.82 21855 23089 2 1519.724968 760.8704 Eukaryotic initiation factor 4A-III OS=Homo sapiens OX=9606 GN=EIF4A3 PE=1 SV=4 3.92 3779.2 - 8.78E+06 - - - -0.8219 - 2.484 0.621 - 302.7 1 2 0 -0.0012 13 0 0 0 1.14E+08 6.28E+07 - - - 5.9625 0.9993 221125_WJC_METTL3_EV_vs_WT_F02.23090.23090.2 0.000727 14/30 R.VSWLGEEPVAGVWSEK[136.11].G "sp|Q9BQ67|GRWD1_HUMAN,tr|M0QX71|M0QX71_HUMAN" 2 1779.8923 0.94 21856 23090 2 1779.897798 890.9534 Glutamate-rich WD repeat-containing protein 1 OS=Homo sapiens OX=9606 GN=GRWD1 PE=1 SV=1 4.25 3779.3 - 2.43E+06 - - - 3.0884 - 2.494 0.453 - 382.9 1 2 0 0.0055 16 0 0 0 5.44E+07 5.78E+07 - - - 4.632 1 221125_WJC_METTL3_EV_vs_WT_F02.23092.23092.2 3.73E-09 15/28 K.VVSNFMDFDETGVLK.G "sp|Q9H0P0|5NT3A_HUMAN,tr|X6RM59|X6RM59_HUMAN" 2 1699.8127 1.43 21858 23092 2 1699.809672 850.9136 Cytosolic 5'-nucleotidase 3A OS=Homo sapiens OX=9606 GN=NT5C3A PE=1 SV=3 4.03 3779.6 - 1.83E+06 - - - -1.7955 - 2.976 0.7 - 611.4 1 2 0 -0.0031 15 0 0 0 1.93E+07 1.34E+07 - - - 6.8915 1 221125_WJC_METTL3_EV_vs_WT_F02.23095.23095.2 2.48E-05 15/30 K.MFIGGLSWQTTQEGLR[166.11].E sp|O43347|MSI1H_HUMAN 1 1832.9119 0.95 21859 23095 2 1832.910877 917.4632 RNA-binding protein Musashi homolog 1 OS=Homo sapiens OX=9606 GN=MSI1 PE=1 SV=1 5.75 3779.9 - 6.21E+06 - - - -0.5439 - 3.215 0.593 - 711.7 1 2 0 -0.001 16 0 0 0 1.19E+08 1.26E+08 - - - 6.2917 0.9999 221125_WJC_METTL3_EV_vs_WT_F02.23096.23096.2 0.000142 24-Oct K.MLVLDEADEMLNK[136.11].G "sp|P38919|IF4A3_HUMAN,tr|I3L3H2|I3L3H2_HUMAN" 2 1527.7404 1.82 21860 23096 2 1527.740134 764.8775 Eukaryotic initiation factor 4A-III OS=Homo sapiens OX=9606 GN=EIF4A3 PE=1 SV=4 3.92 3780 - 4.88E+06 - - - -0.1852 - 2.323 0.536 - 246.1 1 2 0 -0.0003 13 0 0 0 1.14E+08 6.28E+07 - - - 5.163 0.9999 221125_WJC_METTL3_EV_vs_WT_F02.23099.23099.3 0.00217 15/44 K.ADTLTDEINFLR.A "sp|P48668|K2C6C_HUMAN,sp|P04259|K2C6B_HUMAN,sp|P02538|K2C6A_HUMAN" 3 1406.7042 999 21863 23099 3 1406.701656 469.9087 "Keratin, type II cytoskeletal 6C OS=Homo sapiens OX=9606 GN=KRT6C PE=1 SV=3" 4.03 3780.3 - 2.44E+06 - - - -1.7793 - 2.821 0.426 - 359.4 1 2 0 -0.0025 12 0 0 0 5.62E+08 0.00E+00 - - - 6.1634 1 221125_WJC_METTL3_EV_vs_WT_F02.23100.23100.2 3.46E-06 19/32 N.QSLLQPLNVEIDPEIQK.V sp|P04264|K2C1_HUMAN 1 1963.0626 0.03 21864 23100 2 1963.058764 982.5386 "Keratin, type II cytoskeletal 1 OS=Homo sapiens OX=9606 GN=KRT1 PE=1 SV=6" 4.14 3780.4 - 2.05E+06 - - - -1.9577 - 3.363 0.602 - 936.9 1 1 0 -0.0038 17 0 0 0 2.92E+07 9.57E+08 - - - 6.468 0.9868 221125_WJC_METTL3_EV_vs_WT_F02.23102.23102.2 0.445 22-Aug R.TDYWLQPEIIVK[136.11].L "sp|O60870|KIN17_HUMAN,tr|S4R357|S4R357_HUMAN" 2 1511.8115 0.73 21866 23102 2 1511.807964 756.913 DNA\RNA-binding protein KIN17 OS=Homo sapiens OX=9606 GN=KIN PE=1 SV=2 4.37 3780.7 - 715908 - - - -2.3594 - 1.34 0.18 - 120 1 2 0 -0.0036 12 0 0 0 5.68E+06 7.79E+06 - - - 1.1394 1 221125_WJC_METTL3_EV_vs_WT_F02.23107.23107.3 3.81E-07 16/64 R.ALIVVPYAEGVIPDEAK.A "sp|Q05519|SRS11_HUMAN,tr|Q5T760|Q5T760_HUMAN" 2 1782.9768 2.11 21869 23107 3 1782.97541 595.3329 Serine\arginine-rich splicing factor 11 OS=Homo sapiens OX=9606 GN=SRSF11 PE=1 SV=1 4.14 3781.4 - 3.14E+06 - - - -0.7527 - 2.956 0.541 - 289.5 1 2 0 -0.0013 17 0 0 0 5.01E+07 2.38E+07 - - - 7.3093 1 221125_WJC_METTL3_EV_vs_WT_F02.23108.23108.2 1.59E-08 15/24 K.WLLLTGISAQQNR[166.11].V "sp|Q00610|CLH1_HUMAN,tr|A0A087WVQ6|A0A087WVQ6_HUMAN" 2 1508.8339 0.88 21870 23108 2 1508.834062 755.4242 Clathrin heavy chain 1 OS=Homo sapiens OX=9606 GN=CLTC PE=1 SV=5 9.75 3781.5 - 1.41E+06 - - - 0.1193 - 2.943 0.557 - 750.5 1 2 0 0.0002 13 0 0 0 4.47E+07 5.05E+07 - - - 5.9253 0.9998 221125_WJC_METTL3_EV_vs_WT_F02.23110.23110.2 1.64E-05 14/26 K.IEEVLSGVLDTELR.Y "sp|P18583|SON_HUMAN,tr|J3QSZ5|J3QSZ5_HUMAN" 2 1571.8407 3.43 21872 23110 2 1571.841068 786.9276 Protein SON OS=Homo sapiens OX=9606 GN=SON PE=1 SV=4 4 3781.8 - 2.08E+06 - - - 0.264 - 2.911 0.378 - 781.8 1 2 0 0.0004 14 0 0 0 3.32E+07 9.69E+06 - - - 4.5141 0.9999 221125_WJC_METTL3_EV_vs_WT_F02.23111.23111.3 0.000375 20/60 R.IFALLAGKPVWQLSEK.K "sp|P52948|NUP98_HUMAN,tr|H7C3P6|H7C3P6_HUMAN,tr|H0YDF4|H0YDF4_HUMAN" 3 1799.0345 2.51 21873 23111 3 1799.029528 600.6855 Nuclear pore complex protein Nup98-Nup96 OS=Homo sapiens OX=9606 GN=NUP98 PE=1 SV=4 8.59 3781.9 - 1.04E+06 - - - -2.7871 - 3.291 0.435 - 539.6 1 2 0 -0.005 16 0 0 0 1.75E+07 6.97E+06 - - - 6.4449 0.9998 221125_WJC_METTL3_EV_vs_WT_F02.23112.23112.2 1.46E-07 15/30 K.TVIPGMPTVIPPGLTR[166.11].E "sp|Q15637|SF01_HUMAN,tr|C9J792|C9J792_HUMAN,tr|F8WEV5|F8WEV5_HUMAN,tr|A0A7P0T9U7|A0A7P0T9U7_HUMAN" 4 1657.9465 1.09 21874 23112 2 1657.948446 829.9805 Splicing factor 1 OS=Homo sapiens OX=9606 GN=SF1 PE=1 SV=4 9.41 3782 - 823665 - - - 1.1924 - 2.534 0.517 - 559.5 1 2 0 0.002 16 0 0 0 8.64E+07 7.95E+07 - - - 5.1449 1 221125_WJC_METTL3_EV_vs_WT_F02.23113.23113.2 1.38E-06 19/32 K.LTAELIEQAAQYTNAVR[166.11].D "sp|P09661|RU2A_HUMAN,tr|H0YKK0|H0YKK0_HUMAN" 2 1899.993 1.11 21875 23113 2 1899.990331 951.0038 U2 small nuclear ribonucleoprotein A' OS=Homo sapiens OX=9606 GN=SNRPA1 PE=1 SV=2 4.53 3782.1 - 711925 - - - -1.3842 - 3.865 0.535 - 1248.9 1 2 0 -0.0026 17 0 0 0 1.98E+07 1.79E+07 - - - 6.3155 1 221125_WJC_METTL3_EV_vs_WT_F02.23118.23118.2 2.86E-13 22/36 K.VVSQYSSLLSPMSVNAVMK[136.11].V sp|P50991|TCPD_HUMAN 1 2047.0573 0.24 21878 23118 2 2047.055233 1024.5359 T-complex protein 1 subunit delta OS=Homo sapiens OX=9606 GN=CCT4 PE=1 SV=4 8.56 3782.8 - 2.54E+06 - - - -1.0264 - 3.997 0.695 - 1483.2 1 2 0 -0.0021 19 0 0 0 3.20E+07 1.32E+08 - - - 7.58 0.9999 221125_WJC_METTL3_EV_vs_WT_F02.23120.23120.4 1.34E-07 20/120 R.GPLLVQDVVFTDEMAHFDRER.L sp|P04040|CATA_HUMAN 1 2473.206 30.9 21880 23120 4 2473.20636 619.3088 Catalase OS=Homo sapiens OX=9606 GN=CAT PE=1 SV=3 4.43 3783 - 1.76E+06 - - - 0.148 - 3.406 0.532 - 324.7 1 2 1 0.0004 21 0 0 0 1.31E+07 4.25E+05 - - - 4.2616 1 221125_WJC_METTL3_EV_vs_WT_F02.23123.23123.3 3.45E-05 16/56 R.DYLHLPPEIVPATLR[166.11].R "sp|P46783|RS10_HUMAN,tr|A0A2R8Y6L3|A0A2R8Y6L3_HUMAN,tr|F6U211|F6U211_HUMAN,tr|A0A1W2PQS6|A0A1W2PQS6_HUMAN,tr|A0A2R8YFH6|A0A2R8YFH6_HUMAN,tr|A0A2R8Y7H1|A0A2R8Y7H1_HUMAN,tr|S4R435|S4R435_HUMAN" 7 1742.9595 1.36 21882 23123 3 1742.95806 581.9938 40S ribosomal protein S10 OS=Homo sapiens OX=9606 GN=RPS10 PE=1 SV=1 5.32 3783.4 - 2.17E+07 - - - -0.8124 - 2.523 0.473 - 240.9 1 2 0 -0.0014 15 0 0 0 4.38E+08 3.23E+08 - - - 6.2279 1 221125_WJC_METTL3_EV_vs_WT_F02.23124.23124.2 6.81E-05 17/24 K.WLLLTGISAQQNR.V "sp|Q00610|CLH1_HUMAN,tr|A0A087WVQ6|A0A087WVQ6_HUMAN" 2 1498.8256 0.88 21883 23124 2 1498.82571 750.4201 Clathrin heavy chain 1 OS=Homo sapiens OX=9606 GN=CLTC PE=1 SV=5 9.75 3783.5 - 2.48E+06 - - - 0.0654 - 2.963 0.544 - 1107.1 1 2 0 0.0001 13 0 0 0 4.47E+07 5.05E+07 - - - 5.8467 1 221125_WJC_METTL3_EV_vs_WT_F02.23125.23125.3 1.25E-06 16/72 K.VVSQYSSLLSPMSVNAVMK[136.11].V sp|P50991|TCPD_HUMAN 1 2047.0573 0.28 21884 23125 3 2047.055967 683.3597 T-complex protein 1 subunit delta OS=Homo sapiens OX=9606 GN=CCT4 PE=1 SV=4 8.56 3783.5 - 8.02E+06 - - - -0.6678 - 2.908 0.437 - 387.9 1 2 0 -0.0014 19 0 0 0 6.15E+07 2.21E+08 - - - 6.0343 1 221125_WJC_METTL3_EV_vs_WT_F02.23126.23126.2 3.29E-08 16/30 R.VSWLGEEPVAGVWSEK.G "sp|Q9BQ67|GRWD1_HUMAN,tr|M0QX71|M0QX71_HUMAN" 2 1771.8781 0.94 21885 23126 2 1771.880391 886.9463 Glutamate-rich WD repeat-containing protein 1 OS=Homo sapiens OX=9606 GN=GRWD1 PE=1 SV=1 4.25 3783.7 - 2.40E+06 - - - 1.2924 - 2.527 0.6 - 505.8 1 2 0 0.0023 16 0 0 0 5.44E+07 5.78E+07 - - - 5.751 0.9994 221125_WJC_METTL3_EV_vs_WT_F02.23127.23127.2 3.70E-08 14/22 K.FLTDYLNDLQGR[166.11].N "sp|Q6W2J9|BCOR_HUMAN,tr|H7BZ37|H7BZ37_HUMAN,tr|H7C2V9|H7C2V9_HUMAN,tr|H7C231|H7C231_HUMAN" 4 1463.7284 1.71 21886 23127 2 1463.733583 732.8715 BCL-6 corepressor OS=Homo sapiens OX=9606 GN=BCOR PE=1 SV=1 4.21 3783.8 - 1.60E+06 - - - 3.5314 - 2.405 0.548 - 632.3 1 2 0 0.0052 12 0 0 0 6.55E+07 3.83E+07 - - - 5.3959 0.9999 221125_WJC_METTL3_EV_vs_WT_F02.23128.23128.3 1.45E-08 15/52 K.IEEVLSGVLDTELR.Y "sp|P18583|SON_HUMAN,tr|J3QSZ5|J3QSZ5_HUMAN" 2 1571.8407 6.02 21887 23128 3 1571.835424 524.9542 Protein SON OS=Homo sapiens OX=9606 GN=SON PE=1 SV=4 4 3783.9 - 1.14E+06 - - - -3.3267 - 3.178 0.514 - 323.3 1 2 0 -0.0052 14 0 0 0 1.38E+07 2.29E+06 - - - 7.3419 1 221125_WJC_METTL3_EV_vs_WT_F02.23132.23132.2 1.17E-07 15/30 Q.SLLQPLNVEIDPEIQK.V sp|P04264|K2C1_HUMAN 1 1835.004 999 21890 23132 2 1835.003593 918.5093 "Keratin, type II cytoskeletal 1 OS=Homo sapiens OX=9606 GN=KRT1 PE=1 SV=6" 4.14 3784.3 - 3.96E+06 - - - -0.2381 - 2.765 0.585 - 610 1 1 0 -0.0004 16 0 0 0 5.31E+07 0.00E+00 - - - 5.8621 1 221125_WJC_METTL3_EV_vs_WT_F02.23133.23133.3 5.39E-07 16/72 K.VVSQYSSLLSPMSVNAVMK.V sp|P50991|TCPD_HUMAN 1 2039.0431 0.28 21891 23133 3 2039.045634 680.6883 T-complex protein 1 subunit delta OS=Homo sapiens OX=9606 GN=CCT4 PE=1 SV=4 8.56 3784.3 - 2.31E+06 - - - 1.2261 - 3.135 0.564 - 368.3 1 2 0 0.0025 19 0 0 0 6.15E+07 2.21E+08 - - - 7.6346 1 221125_WJC_METTL3_EV_vs_WT_F02.23135.23135.2 2.18E-09 15/36 K.VVSQYSSLLSPMSVNAVMK.V sp|P50991|TCPD_HUMAN 1 2039.0431 0.24 21893 23135 2 2039.043234 1020.5288 T-complex protein 1 subunit delta OS=Homo sapiens OX=9606 GN=CCT4 PE=1 SV=4 8.56 3784.5 - 1.22E+06 - - - 0.049 - 3.255 0.658 - 585.1 1 2 0 0.0001 19 0 0 0 3.20E+07 1.32E+08 - - - 6.8025 0.9998 221125_WJC_METTL3_EV_vs_WT_F02.23138.23138.2 6.61E-05 22-Nov R.GNVGVVLFNFGK.E "sp|P33316|DUT_HUMAN,tr|H0YNJ9|H0YNJ9_HUMAN,tr|H0YMM5|H0YMM5_HUMAN,tr|A0A0C4DGL3|A0A0C4DGL3_HUMAN,tr|H0YKC5|H0YKC5_HUMAN,tr|H0YMP1|H0YMP1_HUMAN,tr|H0YKI0|H0YKI0_HUMAN,tr|H0YNW5|H0YNW5_HUMAN" 8 1249.6819 3.17 21896 23138 2 1249.680006 625.8482 "Deoxyuridine 5'-triphosphate nucleotidohydrolase, mitochondrial OS=Homo sapiens OX=9606 GN=DUT PE=1 SV=4" 8.75 3784.8 - 701324 - - - -1.522 - 2.45 0.468 - 360.4 1 2 0 -0.0019 12 0 0 0 1.49E+07 4.70E+06 - - - 4.8548 0.9998 221125_WJC_METTL3_EV_vs_WT_F02.23140.23140.2 1.38E-06 22-Sep R.LFPPQWIC[160.03]C[160.03]DIR[166.11].Y sp|Q86U44|MTA70_HUMAN 1 1613.7722 0.02 21897 23140 2 1613.769808 807.8934 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 5.82 3785.1 - 7.29E+07 - - - -1.4884 - 1.844 0.563 - 208.4 1 2 0 -0.0024 12 0 0 0 2.52E+07 1.51E+09 - - - 4.8087 1 221125_WJC_METTL3_EV_vs_WT_F02.23141.23141.3 3.66E-06 13/44 R.LFPPQWIC[160.03]C[160.03]DIR[166.11].Y sp|Q86U44|MTA70_HUMAN 1 1613.7722 0.02 21898 23141 3 1613.770553 538.9313 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 5.82 3785.1 - 2.03E+07 - - - -1.0268 - 2.292 0.613 - 225.1 1 2 0 -0.0017 12 0 0 0 5.73E+06 2.96E+08 - - - 7.6729 0.9999 221125_WJC_METTL3_EV_vs_WT_F02.23142.23142.2 7.17E-05 15/28 K.SPAGLQVLNDYLADK.S "sp|P24534|EF1B_HUMAN,tr|F2Z2G2|F2Z2G2_HUMAN,tr|C9JZW3|C9JZW3_HUMAN,tr|F8WF65|F8WF65_HUMAN" 4 1602.8253 0.84 21899 23142 2 1602.825859 802.4199 Elongation factor 1-beta OS=Homo sapiens OX=9606 GN=EEF1B2 PE=1 SV=3 4.21 3785.1 - 9.01E+06 - - - 0.3257 - 3.629 0.452 - 1021.3 1 2 0 0.0005 15 0 0 0 1.77E+08 2.11E+08 - - - 5.5483 0.9999 221125_WJC_METTL3_EV_vs_WT_F02.23143.23143.2 0.0173 22-Dec K.GIDPFSLDALSK[136.11].E sp|P40227|TCPZ_HUMAN 1 1269.6696 0.47 21900 23143 2 1269.669589 635.8421 T-complex protein 1 subunit zeta OS=Homo sapiens OX=9606 GN=CCT6A PE=1 SV=3 4.21 3785.2 - 5.92E+06 - - - -0.0228 - 2.503 0.424 - 434.3 1 2 0 0 12 0 0 0 2.61E+08 5.60E+08 - - - 4.5867 0.9999 221125_WJC_METTL3_EV_vs_WT_F02.23145.23145.2 2.15E-05 30-Dec K.TVIPGMPTVIPPGLTR.E "sp|Q15637|SF01_HUMAN,tr|C9J792|C9J792_HUMAN,tr|F8WEV5|F8WEV5_HUMAN,tr|A0A7P0T9U7|A0A7P0T9U7_HUMAN" 4 1647.9382 1.09 21902 23145 2 1647.939725 824.9764 Splicing factor 1 OS=Homo sapiens OX=9606 GN=SF1 PE=1 SV=4 9.41 3785.3 - 3.40E+06 - - - 0.926 - 2.295 0.552 - 316.1 1 2 0 0.0015 16 0 0 0 9.18E+07 8.44E+07 - - - 5.16 0.9998 221125_WJC_METTL3_EV_vs_WT_F02.23146.23146.2 1.28E-06 15/22 K.FLTDYLNDLQGR.N "sp|Q6W2J9|BCOR_HUMAN,tr|H7BZ37|H7BZ37_HUMAN,tr|H7C2V9|H7C2V9_HUMAN,tr|H7C231|H7C231_HUMAN" 4 1453.7201 1.68 21903 23146 2 1453.716554 727.8673 BCL-6 corepressor OS=Homo sapiens OX=9606 GN=BCOR PE=1 SV=1 4.21 3785.3 - 3.12E+06 - - - -2.4695 - 2.665 0.554 - 752.6 1 2 0 -0.0036 12 0 0 0 6.44E+07 3.83E+07 - - - 5.7108 0.9999 221125_WJC_METTL3_EV_vs_WT_F02.23148.23148.2 0.000611 15/26 K.EAINVEQAFQTIAR.N "sp|P51149|RAB7A_HUMAN,tr|C9J4V0|C9J4V0_HUMAN,tr|A0A6Q8PH84|A0A6Q8PH84_HUMAN,tr|C9J8S3|C9J8S3_HUMAN,tr|C9J4S4|C9J4S4_HUMAN,tr|A0A6Q8PGE6|A0A6Q8PGE6_HUMAN,tr|A0A6Q8PG52|A0A6Q8PG52_HUMAN" 7 1588.8209 1.11 21905 23148 2 1588.821836 795.4177 Ras-related protein Rab-7a OS=Homo sapiens OX=9606 GN=RAB7A PE=1 SV=1 4.53 3785.5 - 2.18E+06 - - - 0.5765 - 3.223 0.472 - 863.8 1 2 0 0.0009 14 0 0 0 3.84E+07 3.46E+07 - - - 5.4637 1 221125_WJC_METTL3_EV_vs_WT_F02.23149.23149.3 7.01E-10 16/64 K.YQVFFFGTHETAFLGPK[136.11].D sp|P51858|HDGF_HUMAN 1 1995.9974 0.05 21906 23149 3 1995.997523 666.3398 Hepatoma-derived growth factor OS=Homo sapiens OX=9606 GN=HDGF PE=1 SV=1 6.75 3785.6 - 2.08E+06 - - - 0.0441 - 3.199 0.606 - 184.5 1 2 0 0.0001 17 0 0 0 7.66E+05 1.52E+07 - - - 8.234 1 221125_WJC_METTL3_EV_vs_WT_F02.23150.23150.2 0.00309 21/32 K.LTAELIEQAAQYTNAVR.D "sp|P09661|RU2A_HUMAN,tr|H0YKK0|H0YKK0_HUMAN" 2 1889.9847 1.11 21907 23150 2 1889.986571 945.9996 U2 small nuclear ribonucleoprotein A' OS=Homo sapiens OX=9606 GN=SNRPA1 PE=1 SV=2 4.53 3785.7 - 1.58E+06 - - - 0.9947 - 3.906 0.553 - 1512 1 2 0 0.0019 17 0 0 0 1.98E+07 1.79E+07 - - - 6.4747 1 221125_WJC_METTL3_EV_vs_WT_F02.23153.23153.3 8.01E-10 20/68 R.VVLLGEFLHPC[160.03]EDDIVC[160.03]K[136.11].C sp|Q9NY12|GAR1_HUMAN 1 2150.0631 1.24 21908 23153 3 2150.055304 717.695 H\ACA ribonucleoprotein complex subunit 1 OS=Homo sapiens OX=9606 GN=GAR1 PE=1 SV=1 4.31 3786.1 - 5.94E+06 - - - -3.6483 - 3.459 0.669 - 359.5 1 2 0 -0.0078 18 0 0 0 2.41E+08 1.94E+08 - - - 9.0867 1 221125_WJC_METTL3_EV_vs_WT_F02.23154.23154.3 4.87E-08 20/52 K.EAINVEQAFQTIAR.N "sp|P51149|RAB7A_HUMAN,tr|C9J4V0|C9J4V0_HUMAN,tr|A0A6Q8PH84|A0A6Q8PH84_HUMAN,tr|C9J8S3|C9J8S3_HUMAN,tr|C9J4S4|C9J4S4_HUMAN,tr|A0A6Q8PGE6|A0A6Q8PGE6_HUMAN,tr|A0A6Q8PG52|A0A6Q8PG52_HUMAN" 7 1588.8209 1.34 21909 23154 3 1588.821085 530.6142 Ras-related protein Rab-7a OS=Homo sapiens OX=9606 GN=RAB7A PE=1 SV=1 4.53 3786.2 - 2.05E+06 - - - 0.1039 - 3.077 0.574 - 476.8 1 2 0 0.0002 14 0 0 0 2.40E+07 1.79E+07 - - - 7.9264 0.9997 221125_WJC_METTL3_EV_vs_WT_F02.23156.23156.2 0.00686 13/26 K.VWQLQDLSFQTAAR[166.11].L sp|Q9NYU2|UGGG1_HUMAN 1 1671.8608 0.02 21911 23156 2 1671.857279 836.9377 UDP-glucose:glycoprotein glucosyltransferase 1 OS=Homo sapiens OX=9606 GN=UGGT1 PE=1 SV=3 5.81 3786.5 - 1.34E+06 - - - -2.121 - 2.786 0.465 - 711.4 1 2 0 -0.0035 14 0 0 0 2.53E+05 1.62E+07 - - - 5.0456 0.9999 221125_WJC_METTL3_EV_vs_WT_F02.23158.23158.3 1.25E-05 13/48 K.WLLLTGISAQQNR.V "sp|Q00610|CLH1_HUMAN,tr|A0A087WVQ6|A0A087WVQ6_HUMAN" 2 1498.8256 1.14 21913 23158 3 1498.829796 500.6158 Clathrin heavy chain 1 OS=Homo sapiens OX=9606 GN=CLTC PE=1 SV=5 9.75 3786.7 - 1.17E+06 - - - 2.7915 - 2.508 0.455 - 284.3 1 2 0 0.0042 13 0 0 0 9.40E+06 8.21E+06 - - - 6.1046 0.993 221125_WJC_METTL3_EV_vs_WT_F02.23161.23161.3 0.122 Sep-36 K.FAAQELIEVK[136.11].R "sp|Q86U44|MTA70_HUMAN,tr|F5H6D8|F5H6D8_HUMAN,tr|H0YFV6|H0YFV6_HUMAN,tr|B4DTN4|B4DTN4_HUMAN" 4 1154.6427 0.001 21916 23161 3 1154.640398 385.8882 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 4.53 3787.1 - 839183 - - - -1.972 - 1.685 0.208 - 94 1 2 0 -0.0023 10 0 0 0 0.00E+00 4.05E+06 - - - 2.3821 0.9998 221125_WJC_METTL3_EV_vs_WT_F02.23166.23166.2 6.53E-05 18-Oct K.FAAQELIEVK[136.11].R "sp|Q86U44|MTA70_HUMAN,tr|F5H6D8|F5H6D8_HUMAN,tr|H0YFV6|H0YFV6_HUMAN,tr|B4DTN4|B4DTN4_HUMAN" 4 1154.6427 0.02 21919 23166 2 1154.641662 578.3286 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 4.53 3787.7 - 7.50E+07 - - - -0.8773 - 1.97 0.493 - 265.5 1 2 0 -0.001 10 0 0 0 3.34E+07 1.56E+09 - - - 4.5746 1 221125_WJC_METTL3_EV_vs_WT_F02.23167.23167.3 1.63E-09 17/68 R.VVLLGEFLHPC[160.03]EDDIVC[160.03]K.C sp|Q9NY12|GAR1_HUMAN 1 2142.0489 1.24 21920 23167 3 2142.044274 715.0236 H\ACA ribonucleoprotein complex subunit 1 OS=Homo sapiens OX=9606 GN=GAR1 PE=1 SV=1 4.31 3787.7 - 1.61E+07 - - - -2.182 - 2.805 0.621 - 284.1 1 2 0 -0.0047 18 0 0 0 2.41E+08 1.94E+08 - - - 8.0305 1 221125_WJC_METTL3_EV_vs_WT_F02.23169.23169.3 5.62E-08 19/56 R.GFLWDEGFHQLVVQR[166.11].W "sp|Q13724|MOGS_HUMAN,tr|A0A3B3IS52|A0A3B3IS52_HUMAN,tr|A0A3B3IRK6|A0A3B3IRK6_HUMAN,tr|A0A3B3IRW2|A0A3B3IRW2_HUMAN" 4 1839.9296 0.73 21922 23169 3 1839.927299 614.3171 Mannosyl-oligosaccharide glucosidase OS=Homo sapiens OX=9606 GN=MOGS PE=1 SV=5 5.32 3787.8 - 4.78E+06 - - - -1.2359 - 3.781 0.636 - 566.6 1 2 0 -0.0023 15 0 0 0 2.34E+07 3.21E+07 - - - 9.1006 0.9999 221125_WJC_METTL3_EV_vs_WT_F02.23170.23170.3 0.000155 17/76 K.ITINPGC[160.03]VVVDGMPPGVSFK.A "sp|P78347|GTF2I_HUMAN,tr|A0A494C1K3|A0A494C1K3_HUMAN" 2 2086.0591 0.82 21923 23170 3 2086.062878 696.3603 General transcription factor II-I OS=Homo sapiens OX=9606 GN=GTF2I PE=1 SV=2 5.83 3787.9 - 1.58E+06 - - - 1.802 - 3.07 0.386 - 178.3 1 2 0 0.0038 20 0 0 0 1.82E+07 2.23E+07 - - - 5.5637 1 221125_WJC_METTL3_EV_vs_WT_F02.23173.23173.3 2.46E-06 16/76 R.MTLDTLSIYETPSMGLLDKK.S sp|P55884|EIF3B_HUMAN 1 2255.1429 1.54 21926 23173 3 2255.143309 752.7216 Eukaryotic translation initiation factor 3 subunit B OS=Homo sapiens OX=9606 GN=EIF3B PE=1 SV=3 4.56 3788.3 - 1.04E+06 - - - 0.1778 - 3.092 0.484 - 193.2 1 2 0 0.0004 20 0 0 0 1.08E+07 7.04E+06 - - - 6.6746 1 221125_WJC_METTL3_EV_vs_WT_F02.23174.23174.2 5.15E-06 18/36 R.GAQAAIVVYDITNTDTFAR.A "sp|P51148|RAB5C_HUMAN,tr|K7ERI8|K7ERI8_HUMAN,tr|K7ENY4|K7ENY4_HUMAN,tr|K7ERQ8|K7ERQ8_HUMAN,tr|F8VVK3|F8VVK3_HUMAN" 5 2025.0167 1.93 21927 23174 2 2025.019266 1013.5156 Ras-related protein Rab-5C OS=Homo sapiens OX=9606 GN=RAB5C PE=1 SV=2 4.21 3788.4 - 998857 - - - 1.2573 - 4.003 0.616 - 1094.4 1 2 0 0.0025 19 0 0 0 1.46E+07 7.52E+06 - - - 7.0001 1 221125_WJC_METTL3_EV_vs_WT_F02.23175.23175.2 1.54E-10 18/36 R.GAQAAIVVYDITNEESFAR[166.11].A sp|P20339|RAB5A_HUMAN 1 2063.0199 -1 21928 23175 2 2063.017728 1032.5172 Ras-related protein Rab-5A OS=Homo sapiens OX=9606 GN=RAB5A PE=1 SV=2 4.14 3788.5 - 826029 - - - -1.0548 - 3.709 0.663 - 809.7 1 2 0 -0.0022 19 0 0 0 0.00E+00 0.00E+00 - - - 7.1598 1 221125_WJC_METTL3_EV_vs_WT_F02.23178.23178.2 5.40E-07 22-Dec K.GIDPFSLDALSK.E sp|P40227|TCPZ_HUMAN 1 1261.6554 0.47 21929 23178 2 1261.655392 631.835 T-complex protein 1 subunit zeta OS=Homo sapiens OX=9606 GN=CCT6A PE=1 SV=3 4.21 3788.9 - 2.96E+07 - - - -0.0206 - 2.388 0.63 - 443.2 1 2 0 0 12 0 0 0 2.61E+08 5.60E+08 - - - 5.9845 0.9999 221125_WJC_METTL3_EV_vs_WT_F02.23180.23180.3 7.98E-06 17/56 R.LADSPPPQVWQLISK.V "sp|P11441|UBL4A_HUMAN,tr|Q5HY81|Q5HY81_HUMAN" 2 1677.909 2.48 21931 23180 3 1677.91008 560.3103 Ubiquitin-like protein 4A OS=Homo sapiens OX=9606 GN=UBL4A PE=1 SV=1 5.84 3789.1 - 2.57E+06 - - - 0.6395 - 2.839 0.406 - 319.7 1 2 0 0.0011 15 0 0 0 1.82E+07 7.36E+06 - - - 5.789 1 221125_WJC_METTL3_EV_vs_WT_F02.23181.23181.2 2.17E-08 19/38 K.EILVGDVGQTVDDPYATFVK.M "sp|P23528|COF1_HUMAN,tr|E9PP50|E9PP50_HUMAN,tr|G3V1A4|G3V1A4_HUMAN,tr|E9PQB7|E9PQB7_HUMAN,tr|E9PK25|E9PK25_HUMAN,tr|E9PLJ3|E9PLJ3_HUMAN,tr|E9PS23|E9PS23_HUMAN" 7 2165.0892 1.58 21932 23181 2 2165.089877 1083.5519 Cofilin-1 OS=Homo sapiens OX=9606 GN=CFL1 PE=1 SV=3 3.84 3789.2 - 2.44E+06 - - - 0.3053 - 3.703 0.645 - 861.6 1 2 0 0.0007 20 0 0 0 4.24E+07 2.68E+07 - - - 7.0234 0.9991 221125_WJC_METTL3_EV_vs_WT_F02.23182.23182.2 6.53E-07 14/28 R.LADSPPPQVWQLISK.V "sp|P11441|UBL4A_HUMAN,tr|Q5HY81|Q5HY81_HUMAN" 2 1677.909 1.85 21933 23182 2 1677.915596 839.9618 Ubiquitin-like protein 4A OS=Homo sapiens OX=9606 GN=UBL4A PE=1 SV=1 5.84 3789.3 - 1.89E+06 - - - 3.9269 - 3.065 0.475 - 597.8 1 2 0 0.0066 15 0 0 0 1.67E+07 9.03E+06 - - - 5.301 1 221125_WJC_METTL3_EV_vs_WT_F02.23183.23183.3 2.12E-07 15/72 R.GAQAAIVVYDITNEESFAR[166.11].A sp|P20339|RAB5A_HUMAN 1 2063.0199 4.61 21934 23183 3 2063.013722 688.6806 Ras-related protein Rab-5A OS=Homo sapiens OX=9606 GN=RAB5A PE=1 SV=2 4.14 3789.5 - 1.89E+06 - - - -2.9966 - 3.405 0.564 - 338.5 1 2 0 -0.0062 19 0 0 0 7.62E+07 1.65E+07 - - - 7.8365 1 221125_WJC_METTL3_EV_vs_WT_F02.23185.23185.2 5.24E-08 13/24 R.MAVQDAVDALMQK.A sp|P46060|RAGP1_HUMAN 1 1418.6898 0.25 21936 23185 2 1418.690278 710.3522 Ran GTPase-activating protein 1 OS=Homo sapiens OX=9606 GN=RANGAP1 PE=1 SV=1 4.21 3789.7 - 1.53E+06 - - - 0.3567 - 2.839 0.572 - 566 1 2 0 0.0005 13 0 0 0 1.36E+07 5.44E+07 - - - 5.9437 1 221125_WJC_METTL3_EV_vs_WT_F02.23186.23186.2 7.63E-08 14/28 R.LADSPPPQVWQLISK[136.11].V "sp|P11441|UBL4A_HUMAN,tr|Q5HY81|Q5HY81_HUMAN" 2 1685.9232 1.85 21937 23186 2 1685.928301 843.9689 Ubiquitin-like protein 4A OS=Homo sapiens OX=9606 GN=UBL4A PE=1 SV=1 5.84 3789.9 - 1.03E+06 - - - 3.0215 - 2.928 0.572 - 660.4 1 2 0 0.0051 15 0 0 0 1.67E+07 9.03E+06 - - - 5.9055 0.9999 221125_WJC_METTL3_EV_vs_WT_F02.23190.23190.2 6.10E-05 28-Nov R.DYLHLPPEIVPATLR.R "sp|P46783|RS10_HUMAN,tr|A0A2R8Y6L3|A0A2R8Y6L3_HUMAN,tr|F6U211|F6U211_HUMAN,tr|A0A1W2PQS6|A0A1W2PQS6_HUMAN,tr|A0A2R8YFH6|A0A2R8YFH6_HUMAN,tr|A0A2R8Y7H1|A0A2R8Y7H1_HUMAN,tr|S4R435|S4R435_HUMAN" 7 1732.9512 1.33 21940 23190 2 1732.952274 867.4829 40S ribosomal protein S10 OS=Homo sapiens OX=9606 GN=RPS10 PE=1 SV=1 5.32 3790.4 - 1.10E+06 - - - 0.6163 - 2.221 0.514 - 130 1 2 0 0.0011 15 0 0 0 3.81E+07 2.86E+07 - - - 4.7989 1 221125_WJC_METTL3_EV_vs_WT_F02.23192.23192.2 6.83E-12 16/28 R.FTPGTFTNQIQAAFR.E "sp|P08865|RSSA_HUMAN,tr|C9J9K3|C9J9K3_HUMAN,tr|A0A0C4DG17|A0A0C4DG17_HUMAN" 3 1697.8526 0.68 21941 23192 2 1697.851927 849.9336 40S ribosomal protein SA OS=Homo sapiens OX=9606 GN=RPSA PE=1 SV=4 9.75 3790.6 - 5.17E+06 - - - -0.3699 - 3.141 0.657 - 1167.7 1 2 0 -0.0006 15 0 0 0 4.40E+07 6.46E+07 - - - 6.7073 1 221125_WJC_METTL3_EV_vs_WT_F02.23193.23193.3 1.36E-06 Dec-56 R.FTPGTFTNQIQAAFR[166.11].E "sp|P08865|RSSA_HUMAN,tr|C9J9K3|C9J9K3_HUMAN,tr|A0A0C4DG17|A0A0C4DG17_HUMAN" 3 1707.8608 0.65 21942 23193 3 1707.858514 570.2942 40S ribosomal protein SA OS=Homo sapiens OX=9606 GN=RPSA PE=1 SV=4 9.75 3790.6 - 4.29E+06 - - - -1.3532 - 2.506 0.519 - 186.7 1 2 0 -0.0023 15 0 0 0 1.70E+07 2.60E+07 - - - 6.7229 0.9999 221125_WJC_METTL3_EV_vs_WT_F02.23194.23194.3 1.00E-05 Nov-56 R.FTPGTFTNQIQAAFR.E "sp|P08865|RSSA_HUMAN,tr|C9J9K3|C9J9K3_HUMAN,tr|A0A0C4DG17|A0A0C4DG17_HUMAN" 3 1697.8526 0.65 21943 23194 3 1697.851843 566.9581 40S ribosomal protein SA OS=Homo sapiens OX=9606 GN=RPSA PE=1 SV=4 9.75 3790.7 - 3.00E+06 - - - -0.4194 - 1.979 0.444 - 60.3 1 2 0 -0.0007 15 0 0 0 1.70E+07 2.60E+07 - - - 5.2711 0.9824 221125_WJC_METTL3_EV_vs_WT_F02.23195.23195.2 3.75E-05 18-Dec K.FAAQELIEVK.R "sp|Q86U44|MTA70_HUMAN,tr|F5H6D8|F5H6D8_HUMAN,tr|H0YFV6|H0YFV6_HUMAN,tr|B4DTN4|B4DTN4_HUMAN" 4 1146.6285 0.02 21944 23195 2 1147.629243 574.3215 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 4.53 3790.7 - 2.87E+06 - - - 872.7919 - 2.131 0.472 - 346.3 1 2 0 1.0008 10 0 0 0 3.34E+07 1.56E+09 - - - 4.3248 1 221125_WJC_METTL3_EV_vs_WT_F02.23196.23196.2 1.21E-10 21/36 R.GAQAAIVVYDITNTDTFAR[166.11].A "sp|P51148|RAB5C_HUMAN,tr|K7ERI8|K7ERI8_HUMAN,tr|K7ENY4|K7ENY4_HUMAN,tr|K7ERQ8|K7ERQ8_HUMAN,tr|F8VVK3|F8VVK3_HUMAN" 5 2035.025 -1 21945 23196 2 2035.019238 1018.5198 Ras-related protein Rab-5C OS=Homo sapiens OX=9606 GN=RAB5C PE=1 SV=2 4.21 3790.9 - 2.26E+06 - - - -2.8265 - 4.297 0.645 - 1676.6 1 2 0 -0.0058 19 0 0 0 0.00E+00 0.00E+00 - - - 7.3875 0.9999 221125_WJC_METTL3_EV_vs_WT_F02.23197.23197.2 4.64E-07 28-Dec R.DYLHLPPEIVPATLR[166.11].R "sp|P46783|RS10_HUMAN,tr|A0A2R8Y6L3|A0A2R8Y6L3_HUMAN,tr|F6U211|F6U211_HUMAN,tr|A0A1W2PQS6|A0A1W2PQS6_HUMAN,tr|A0A2R8YFH6|A0A2R8YFH6_HUMAN,tr|A0A2R8Y7H1|A0A2R8Y7H1_HUMAN,tr|S4R435|S4R435_HUMAN" 7 1742.9595 1.34 21946 23197 2 1742.959814 872.487 40S ribosomal protein S10 OS=Homo sapiens OX=9606 GN=RPS10 PE=1 SV=1 5.32 3791 - 1.56E+06 - - - 0.1939 - 2.408 0.567 - 219.6 1 2 0 0.0003 15 0 0 0 3.99E+07 2.98E+07 - - - 5.3893 1 221125_WJC_METTL3_EV_vs_WT_F02.23199.23199.3 0.000291 17/56 R.LADSPPPQVWQLISK[136.11].V "sp|P11441|UBL4A_HUMAN,tr|Q5HY81|Q5HY81_HUMAN" 2 1685.9232 2.48 21948 23199 3 1685.925225 562.9817 Ubiquitin-like protein 4A OS=Homo sapiens OX=9606 GN=UBL4A PE=1 SV=1 5.84 3791.2 - 1.22E+06 - - - 1.197 - 3.486 0.534 - 459.3 1 2 0 0.002 15 0 0 0 1.82E+07 7.36E+06 - - - 7.7515 1 221125_WJC_METTL3_EV_vs_WT_F02.23201.23201.2 2.64E-10 16/38 K.ITINPGC[160.03]VVVDGMPPGVSFK.A "sp|P78347|GTF2I_HUMAN,tr|A0A494C1K3|A0A494C1K3_HUMAN" 2 2086.0591 2.55 21950 23201 2 2086.065503 1044.0368 General transcription factor II-I OS=Homo sapiens OX=9606 GN=GTF2I PE=1 SV=2 5.83 3791.5 - 858726 - - - 3.0603 - 3.166 0.635 - 364.4 1 2 0 0.0064 20 0 0 0 8.23E+06 3.22E+06 - - - 6.5625 1 221125_WJC_METTL3_EV_vs_WT_F02.23202.23202.2 1.17E-06 17/34 K.SEGALELADVSNELPGLK.W sp|Q08J23|NSUN2_HUMAN 1 1840.9418 1.48 21951 23202 2 1840.94523 921.4782 RNA cytosine C(5)-methyltransferase NSUN2 OS=Homo sapiens OX=9606 GN=NSUN2 PE=1 SV=2 4 3791.6 - 806187 - - - 1.8501 - 3.578 0.572 - 609.6 1 2 0 0.0034 18 0 0 0 1.47E+07 9.96E+06 - - - 6.3989 0.9997 221125_WJC_METTL3_EV_vs_WT_F02.23203.23203.2 0.0506 13/26 R.TPTEALASFDYIVR.E "sp|Q9H7Z7|PGES2_HUMAN,tr|A0A7I2V5T7|A0A7I2V5T7_HUMAN,tr|A6NHH0|A6NHH0_HUMAN,tr|X6RJ95|X6RJ95_HUMAN,tr|A0A7I2V5X6|A0A7I2V5X6_HUMAN" 5 1581.8039 1.03 21952 23203 2 1581.801455 791.9092 Prostaglandin E synthase 2 OS=Homo sapiens OX=9606 GN=PTGES2 PE=1 SV=1 4.37 3791.7 - 760321 - - - -1.5286 - 2.596 0.388 - 295.1 1 2 0 -0.0024 14 0 0 0 1.39E+07 1.35E+07 - - - 4.3 0.9996 221125_WJC_METTL3_EV_vs_WT_F02.23205.23205.3 0.0104 16/44 K.DFINFISDK[136.11]EWK[136.11].S sp|Q9H3N1|TMX1_HUMAN 1 1556.7846 1.31 21954 23205 3 1556.78708 519.9355 Thioredoxin-related transmembrane protein 1 OS=Homo sapiens OX=9606 GN=TMX1 PE=1 SV=1 4.56 3792 - 595007 - - - 1.5962 - 2.756 0.39 - 265.7 1 2 1 0.0025 12 0 0 0 3.13E+06 2.39E+06 - - - 5.6975 0.9864 221125_WJC_METTL3_EV_vs_WT_F02.23206.23206.2 0.331 Sep-34 K.IYSVEALPVAAVNVQSTQ.- sp|Q9NYY8|FAKD2_HUMAN 1 1887.9942 - 21955 23206 2 1887.989765 945.0044 "FAST kinase domain-containing protein 2, mitochondrial OS=Homo sapiens OX=9606 GN=FASTKD2 PE=1 SV=1" 4 3792.1 - 349335 - - - -2.3453 - 1.663 0.111 - 157.6 1 2 0 -0.0044 18 0 0 0 - - - - - 1.1099 1 221125_WJC_METTL3_EV_vs_WT_F02.23208.23208.3 2.50E-09 18/76 K.EILVGDVGQTVDDPYATFVK.M "sp|P23528|COF1_HUMAN,tr|E9PP50|E9PP50_HUMAN,tr|G3V1A4|G3V1A4_HUMAN,tr|E9PQB7|E9PQB7_HUMAN,tr|E9PK25|E9PK25_HUMAN,tr|E9PLJ3|E9PLJ3_HUMAN,tr|E9PS23|E9PS23_HUMAN" 7 2165.0892 1.77 21956 23208 3 2165.089613 722.7037 Cofilin-1 OS=Homo sapiens OX=9606 GN=CFL1 PE=1 SV=3 3.84 3792.3 - 2.35E+07 - - - 0.1834 - 3.371 0.611 - 401.2 1 2 0 0.0004 20 0 0 0 9.37E+07 5.29E+07 - - - 8.3001 1 221125_WJC_METTL3_EV_vs_WT_F02.23209.23209.2 8.76E-11 13/28 R.FTPGTFTNQIQAAFR[166.11].E "sp|P08865|RSSA_HUMAN,tr|C9J9K3|C9J9K3_HUMAN,tr|A0A0C4DG17|A0A0C4DG17_HUMAN" 3 1707.8608 0.68 21957 23209 2 1707.860608 854.9377 40S ribosomal protein SA OS=Homo sapiens OX=9606 GN=RPSA PE=1 SV=4 9.75 3792.4 - 1.03E+07 - - - -0.1271 - 2.992 0.682 - 645.5 1 2 0 -0.0002 15 0 0 0 4.40E+07 6.46E+07 - - - 6.7726 1 221125_WJC_METTL3_EV_vs_WT_F02.23210.23210.3 4.16E-12 18/80 M.PGGLLLGDVAPNFEANTTVGR.L sp|P30041|PRDX6_HUMAN 1 2097.0855 1.4 21958 23210 3 2097.086902 700.0358 Peroxiredoxin-6 OS=Homo sapiens OX=9606 GN=PRDX6 PE=1 SV=3 4.37 3792.4 - 5.50E+06 - - - 0.6838 - 3.956 0.665 - 458.1 1 2 0 0.0014 21 0 0 0 3.54E+07 2.53E+07 - - - 9.2508 0.9998 221125_WJC_METTL3_EV_vs_WT_F02.23211.23211.2 6.54E-06 Oct-32 K.TTPPVLDSDGSFFLYSK.L "sp|P01857|IGHG1_HUMAN,tr|A0A0A0MS08|A0A0A0MS08_HUMAN,tr|A0A0A0MS07|A0A0A0MS07_HUMAN" 3 1872.9145 19.98 21959 23211 2 1872.914112 937.4645 Immunoglobulin heavy constant gamma 1 OS=Homo sapiens OX=9606 GN=IGHG1 PE=1 SV=1 4.21 3792.5 - 3.22E+06 - - - -0.2317 - 2.147 0.482 - 164.6 1 2 0 -0.0004 17 0 0 0 1.72E+07 8.63E+05 - - - 4.4794 0.9995 221125_WJC_METTL3_EV_vs_WT_F02.23213.23213.2 3.77E-05 14/24 K.LSLAEIYEQEYIK.L sp|O00566|MPP10_HUMAN 1 1597.8239 1.34 21961 23213 2 1597.82911 799.9192 U3 small nucleolar ribonucleoprotein protein MPP10 OS=Homo sapiens OX=9606 GN=MPHOSPH10 PE=1 SV=2 4.25 3792.6 - 2.51E+06 - - - 3.2357 - 3.112 0.46 - 932 1 2 0 0.0052 13 0 0 0 3.32E+07 2.48E+07 - - - 5.3506 0.9989 221125_WJC_METTL3_EV_vs_WT_F02.23215.23215.2 0.000406 16-Sep K.DAEDWFFSK.T "sp|Q04695|K1C17_HUMAN,tr|K7ESE1|K7ESE1_HUMAN,tr|F5GWP8|F5GWP8_HUMAN" 3 1143.4873 999 21963 23215 2 1143.486173 572.7509 "Keratin, type I cytoskeletal 17 OS=Homo sapiens OX=9606 GN=KRT17 PE=1 SV=2" 4.03 3792.8 - 1.94E+06 - - - -0.9768 - 1.967 0.193 - 287.2 1 2 0 -0.0011 9 0 0 0 7.98E+08 0.00E+00 - - - 2.4233 0.9998 221125_WJC_METTL3_EV_vs_WT_F02.23217.23217.2 0.000868 13/28 K.SINGILFPGGSVDLR.R "sp|Q92820|GGH_HUMAN,tr|A0A7I2YQQ3|A0A7I2YQQ3_HUMAN,tr|A0A7I2V5X9|A0A7I2V5X9_HUMAN,tr|A0A7I2V5P2|A0A7I2V5P2_HUMAN" 4 1543.8358 5.78 21965 23217 2 1543.834862 772.9252 Gamma-glutamyl hydrolase OS=Homo sapiens OX=9606 GN=GGH PE=1 SV=2 5.55 3792.9 - 1.73E+06 - - - -0.6348 - 2.31 0.451 - 461.2 1 2 0 -0.001 15 0 0 0 1.00E+07 1.74E+06 - - - 4.4302 1 221125_WJC_METTL3_EV_vs_WT_F02.23218.23218.2 5.86E-07 15/28 K.IEENATGFSYESLFR.E "sp|Q8WV92|MITD1_HUMAN,tr|B8ZZL5|B8ZZL5_HUMAN,tr|H7C3Q6|H7C3Q6_HUMAN" 3 1761.821 1.24 21966 23218 2 1761.819292 881.9178 MIT domain-containing protein 1 OS=Homo sapiens OX=9606 GN=MITD1 PE=1 SV=1 4.25 3793 - 1.67E+06 - - - -0.9581 - 3.115 0.66 - 756.7 1 2 0 -0.0017 15 0 0 0 1.57E+07 1.27E+07 - - - 6.7087 1 221125_WJC_METTL3_EV_vs_WT_F02.23219.23219.2 6.97E-08 16/28 R.YLNTNPVGGLLEYAR[166.11].S "sp|P55265|DSRAD_HUMAN,tr|A0A3B3IRQ9|A0A3B3IRQ9_HUMAN,tr|A0A3B3ISU1|A0A3B3ISU1_HUMAN,tr|A0A7P0Z4K3|A0A7P0Z4K3_HUMAN,tr|A0A3B3ISX1|A0A3B3ISX1_HUMAN,tr|A0A7P0Z4F9|A0A7P0Z4F9_HUMAN" 6 1688.8761 0.67 21967 23219 2 1688.876557 845.4453 Double-stranded RNA-specific adenosine deaminase OS=Homo sapiens OX=9606 GN=ADAR PE=1 SV=4 6 3793.1 - 1.65E+06 - - - 0.2463 - 3.244 0.61 - 652.5 1 2 0 0.0004 15 0 0 0 1.55E+07 2.31E+07 - - - 6.4396 0.9995 221125_WJC_METTL3_EV_vs_WT_F02.23226.23226.3 0.005 Dec-60 K.TVIPGMPTVIPPGLTR[166.11].E "sp|Q15637|SF01_HUMAN,tr|C9J792|C9J792_HUMAN,tr|F8WEV5|F8WEV5_HUMAN,tr|A0A7P0T9U7|A0A7P0T9U7_HUMAN" 4 1657.9465 2.1 21974 23226 3 1657.948747 553.6561 Splicing factor 1 OS=Homo sapiens OX=9606 GN=SF1 PE=1 SV=4 9.41 3794 - 793561 - - - 1.374 - 2.131 0.322 - 166.6 1 2 0 0.0023 16 0 0 0 3.25E+07 1.55E+07 - - - 4.0707 0.9994 221125_WJC_METTL3_EV_vs_WT_F02.23227.23227.3 0.0117 13/44 K.DFINFISDKEWK.S sp|Q9H3N1|TMX1_HUMAN 1 1540.7562 1.31 21975 23227 3 1540.754907 514.5927 Thioredoxin-related transmembrane protein 1 OS=Homo sapiens OX=9606 GN=TMX1 PE=1 SV=1 4.56 3794.1 - 785228 - - - -0.836 - 2.309 0.371 - 174.3 1 2 1 -0.0013 12 0 0 0 3.13E+06 2.39E+06 - - - 4.9955 0.9999 221125_WJC_METTL3_EV_vs_WT_F02.23231.23231.2 8.96E-07 20-Nov K.YFSLPFC[160.03]VGSK.K "sp|Q9HD45|TM9S3_HUMAN,tr|Q5TB53|Q5TB53_HUMAN" 2 1303.6271 1.33 21978 23231 2 1303.627582 652.8208 Transmembrane 9 superfamily member 3 OS=Homo sapiens OX=9606 GN=TM9SF3 PE=1 SV=2 8.2 3794.5 - 1.13E+07 - - - 0.3736 - 2.049 0.602 - 358.5 1 2 0 0.0005 11 0 0 0 8.92E+07 6.70E+07 - - - 5.4278 0.9993 221125_WJC_METTL3_EV_vs_WT_F02.23232.23232.2 0.000312 20-Sep K.YFSLPFC[160.03]VGSK[136.11].K "sp|Q9HD45|TM9S3_HUMAN,tr|Q5TB53|Q5TB53_HUMAN" 2 1311.6413 1.33 21979 23232 2 1311.642565 656.8279 Transmembrane 9 superfamily member 3 OS=Homo sapiens OX=9606 GN=TM9SF3 PE=1 SV=2 8.2 3794.6 - 1.02E+07 - - - 0.9683 - 1.654 0.355 - 152.9 1 2 0 0.0013 11 0 0 0 8.92E+07 6.70E+07 - - - 3.0239 0.9999 221125_WJC_METTL3_EV_vs_WT_F02.23233.23233.2 0.000428 13/22 R.EGDVLTLLESER[166.11].E sp|P62857|RS28_HUMAN 1 1369.6964 1.02 21980 23233 2 1369.696745 685.8555 40S ribosomal protein S28 OS=Homo sapiens OX=9606 GN=RPS28 PE=1 SV=1 4 3794.6 - 8.48E+06 - - - 0.219 - 2.55 0.523 - 526.3 1 2 0 0.0003 12 0 0 0 3.30E+08 3.24E+08 - - - 5.3668 1 221125_WJC_METTL3_EV_vs_WT_F02.23234.23234.2 1.22E-05 15/22 R.EGDVLTLLESER.E sp|P62857|RS28_HUMAN 1 1359.6882 1.02 21981 23234 2 1359.688067 680.8514 40S ribosomal protein S28 OS=Homo sapiens OX=9606 GN=RPS28 PE=1 SV=1 4 3794.6 - 7.95E+06 - - - -0.0794 - 2.873 0.559 - 802.6 1 2 0 -0.0001 12 0 0 0 3.30E+08 3.24E+08 - - - 5.9466 0.9988 221125_WJC_METTL3_EV_vs_WT_F02.23235.23235.3 2.71E-09 13/60 A.SLNLEETLSTLEYAHR.A "sp|P52732|KIF11_HUMAN,tr|A0A7I2YQY4|A0A7I2YQY4_HUMAN,tr|A0A7I2V3A9|A0A7I2V3A9_HUMAN,tr|A0A7I2V3V3|A0A7I2V3V3_HUMAN" 4 1874.9374 7.91 21982 23235 3 1874.937366 625.9864 Kinesin-like protein KIF11 OS=Homo sapiens OX=9606 GN=KIF11 PE=1 SV=2 4.75 3794.7 - 2.84E+06 - - - -0.0219 - 2.913 0.609 - 177.1 1 1 0 0 16 0 0 0 9.53E+06 1.21E+06 - - - 8.0731 1 221125_WJC_METTL3_EV_vs_WT_F02.23236.23236.2 2.13E-08 25/40 M.PGGLLLGDVAPNFEANTTVGR.L sp|P30041|PRDX6_HUMAN 1 2097.0855 1.11 21983 23236 2 2097.087541 1049.55 Peroxiredoxin-6 OS=Homo sapiens OX=9606 GN=PRDX6 PE=1 SV=3 4.37 3794.8 - 2.00E+06 - - - 0.9885 - 4.435 0.67 - 1882 1 2 0 0.0021 21 0 0 0 9.98E+06 8.98E+06 - - - 7.651 0.9998 221125_WJC_METTL3_EV_vs_WT_F02.23239.23239.2 3.81E-05 26-Dec K.LSPESAEEYIEYLK.S sp|Q9HCS7|SYF1_HUMAN 1 1669.8087 2.47 21986 23239 2 1669.806108 835.9116 Pre-mRNA-splicing factor SYF1 OS=Homo sapiens OX=9606 GN=XAB2 PE=1 SV=2 4.09 3795.1 - 1.10E+06 - - - -1.5427 - 2.425 0.524 - 459.4 1 2 0 -0.0026 14 0 0 0 9.92E+06 4.02E+06 - - - 5.1334 0.9999 221125_WJC_METTL3_EV_vs_WT_F02.23240.23240.3 3.40E-05 Sep-56 K.IEENATGFSYESLFR[166.11].E "sp|Q8WV92|MITD1_HUMAN,tr|B8ZZL5|B8ZZL5_HUMAN,tr|H7C3Q6|H7C3Q6_HUMAN" 3 1771.8293 -1 21987 23240 3 1771.829917 591.617 MIT domain-containing protein 1 OS=Homo sapiens OX=9606 GN=MITD1 PE=1 SV=1 4.25 3795.2 - 903254 - - - 0.3764 - 1.922 0.501 - 98.9 1 2 0 0.0007 15 0 0 0 0.00E+00 0.00E+00 - - - 5.8303 1 221125_WJC_METTL3_EV_vs_WT_F02.23241.23241.2 1.54E-07 16/24 K.IDPAYFDENWLNR.L sp|Q86VS8|HOOK3_HUMAN 1 1651.7631 -1 21988 23241 2 1651.766594 826.8888 Protein Hook homolog 3 OS=Homo sapiens OX=9606 GN=HOOK3 PE=1 SV=2 4.03 3795.3 - 714457 - - - 2.1329 - 2.938 0.626 - 953.3 1 2 0 0.0035 13 0 0 0 0.00E+00 0.00E+00 - - - 6.4296 1 221125_WJC_METTL3_EV_vs_WT_F02.23242.23242.2 9.13E-10 17/30 K.ITISSLQDLSIYNPER.T "sp|Q9Y6M1|IF2B2_HUMAN,tr|F8W930|F8W930_HUMAN" 2 1847.9629 -1 21989 23242 2 1847.967241 924.9887 Insulin-like growth factor 2 mRNA-binding protein 2 OS=Homo sapiens OX=9606 GN=IGF2BP2 PE=1 SV=2 4.37 3795.4 - 626481 - - - 2.3529 - 3.443 0.642 - 1188.6 1 2 0 0.0043 16 0 0 0 0.00E+00 0.00E+00 - - - 6.8211 1 221125_WJC_METTL3_EV_vs_WT_F02.23246.23246.3 7.47E-06 16/60 K.TVIPGMPTVIPPGLTR.E "sp|Q15637|SF01_HUMAN,tr|C9J792|C9J792_HUMAN,tr|F8WEV5|F8WEV5_HUMAN,tr|A0A7P0T9U7|A0A7P0T9U7_HUMAN" 4 1647.9382 2.1 21993 23246 3 1647.93967 550.32 Splicing factor 1 OS=Homo sapiens OX=9606 GN=SF1 PE=1 SV=4 9.41 3795.9 - 491587 - - - 0.8926 - 2.45 0.473 - 280.7 1 2 0 0.0015 16 0 0 0 3.25E+07 1.55E+07 - - - 6.1123 1 221125_WJC_METTL3_EV_vs_WT_F02.23247.23247.2 4.00E-07 16/30 R.SFITTDVNPYYDSFVR.W "sp|Q9P2J5|SYLC_HUMAN,tr|A0A6I8PIV1|A0A6I8PIV1_HUMAN,tr|A0A6I8PRS0|A0A6I8PRS0_HUMAN,tr|A0A6I8PLB8|A0A6I8PLB8_HUMAN,tr|A0A6I8PIP7|A0A6I8PIP7_HUMAN,tr|A0A6I8PIT3|A0A6I8PIT3_HUMAN,tr|A0A6I8PTV8|A0A6I8PTV8_HUMAN,tr|A0A6I8PRU9|A0A6I8PRU9_HUMAN,tr|A0A6I8PLB3|A0A6I8PLB3_HUMAN,tr|A0A6I8PS05|A0A6I8PS05_HUMAN,tr|B4DER1|B4DER1_HUMAN,tr|A0A6I8PL42|A0A6I8PL42_HUMAN" 12 1922.905 -1 21994 23247 2 1922.901611 962.4598 "Leucine--tRNA ligase, cytoplasmic OS=Homo sapiens OX=9606 GN=LARS1 PE=1 SV=2" 4.21 3796.1 - 489024 - - - -1.7853 - 3.15 0.632 - 741.4 1 2 0 -0.0034 16 0 0 0 0.00E+00 0.00E+00 - - - 6.5288 0.9999 221125_WJC_METTL3_EV_vs_WT_F02.23250.23250.2 3.08E-05 28-Dec R.YLNTNPVGGLLEYAR.S "sp|P55265|DSRAD_HUMAN,tr|A0A3B3IRQ9|A0A3B3IRQ9_HUMAN,tr|A0A3B3ISU1|A0A3B3ISU1_HUMAN,tr|A0A7P0Z4K3|A0A7P0Z4K3_HUMAN,tr|A0A3B3ISX1|A0A3B3ISX1_HUMAN,tr|A0A7P0Z4F9|A0A7P0Z4F9_HUMAN" 6 1678.8679 0.67 21996 23250 2 1678.868445 840.4412 Double-stranded RNA-specific adenosine deaminase OS=Homo sapiens OX=9606 GN=ADAR PE=1 SV=4 6 3796.5 - 3.81E+06 - - - 0.3419 - 2.89 0.478 - 314.4 1 2 0 0.0006 15 0 0 0 1.55E+07 2.31E+07 - - - 5.1805 1 221125_WJC_METTL3_EV_vs_WT_F02.23252.23252.2 5.95E-07 13/24 R.SIQFVDWC[160.03]PTGFK[136.11].V "sp|P68366|TBA4A_HUMAN,sp|P68363|TBA1B_HUMAN" 2 1591.7585 0.54 21998 23252 2 1591.75812 796.8865 Tubulin alpha-4A chain OS=Homo sapiens OX=9606 GN=TUBA4A PE=1 SV=1 5.55 3796.6 - 2.33E+07 - - - -0.2073 - 2.635 0.57 - 607.4 1 2 0 -0.0003 13 0 0 0 9.38E+07 1.73E+08 - - - 5.7376 1 221125_WJC_METTL3_EV_vs_WT_F02.23253.23253.3 1.46E-08 Dec-56 R.DYLHLPPEIVPATLR.R "sp|P46783|RS10_HUMAN,tr|A0A2R8Y6L3|A0A2R8Y6L3_HUMAN,tr|F6U211|F6U211_HUMAN,tr|A0A1W2PQS6|A0A1W2PQS6_HUMAN,tr|A0A2R8YFH6|A0A2R8YFH6_HUMAN,tr|A0A2R8Y7H1|A0A2R8Y7H1_HUMAN,tr|S4R435|S4R435_HUMAN" 7 1732.9512 1.35 21999 23253 3 1732.950599 578.6577 40S ribosomal protein S10 OS=Homo sapiens OX=9606 GN=RPS10 PE=1 SV=1 5.32 3796.6 - 2.21E+07 - - - -0.3503 - 2.573 0.57 - 112.2 1 2 0 -0.0006 15 0 0 0 4.31E+08 3.19E+08 - - - 7.3608 0.9999 221125_WJC_METTL3_EV_vs_WT_F02.23254.23254.2 5.74E-07 24-Dec R.SIQFVDWC[160.03]PTGFK.V "sp|P68366|TBA4A_HUMAN,sp|P68363|TBA1B_HUMAN" 2 1583.7442 0.54 22000 23254 2 1583.744287 792.8794 Tubulin alpha-4A chain OS=Homo sapiens OX=9606 GN=TUBA4A PE=1 SV=1 5.55 3796.6 - 1.18E+07 - - - 0.0234 - 2.23 0.583 - 457 1 2 0 0 13 0 0 0 9.38E+07 1.73E+08 - - - 5.4054 1 221125_WJC_METTL3_EV_vs_WT_F02.23255.23255.3 3.54E-10 15/56 R.HFYWYLTNEGIQYLR[166.11].D "sp|P46783|RS10_HUMAN,tr|A0A2R8Y6L3|A0A2R8Y6L3_HUMAN,tr|F6U211|F6U211_HUMAN,tr|A0A1W2PQS6|A0A1W2PQS6_HUMAN,tr|A0A2R8YFH6|A0A2R8YFH6_HUMAN,tr|A0A2R8Y7H1|A0A2R8Y7H1_HUMAN,tr|S4R435|S4R435_HUMAN" 7 2011.982 1.11 22001 23255 3 2011.981705 671.6679 40S ribosomal protein S10 OS=Homo sapiens OX=9606 GN=RPS10 PE=1 SV=1 6.75 3796.7 - 4.98E+06 - - - -0.1481 - 3.098 0.618 - 366.1 1 2 0 -0.0003 15 0 0 0 2.24E+08 2.03E+08 - - - 8.3806 0.9998 221125_WJC_METTL3_EV_vs_WT_F02.23257.23257.2 0.000168 24-Dec K.DFLAGGIAAAISK[136.11].T sp|P12236|ADT3_HUMAN 1 1240.6907 0.99 22003 23257 2 1240.692214 621.3526 ADP\ATP translocase 3 OS=Homo sapiens OX=9606 GN=SLC25A6 PE=1 SV=4 5.84 3796.8 - 2.86E+06 - - - 1.23 - 2.345 0.48 - 360.4 1 2 0 0.0015 13 0 0 0 3.64E+07 3.68E+07 - - - 4.7732 0.9999 221125_WJC_METTL3_EV_vs_WT_F02.23258.23258.3 0.000338 Nov-44 R.EGDVLTLLESER[166.11].E sp|P62857|RS28_HUMAN 1 1369.6964 0.97 22004 23258 3 1369.694541 457.5728 40S ribosomal protein S28 OS=Homo sapiens OX=9606 GN=RPS28 PE=1 SV=1 4 3796.9 - 2.46E+06 - - - -1.3901 - 2.209 0.439 - 205.6 1 2 0 -0.0019 12 0 0 0 1.44E+07 1.48E+07 - - - 5.6307 0.9998 221125_WJC_METTL3_EV_vs_WT_F02.23259.23259.2 3.10E-05 18-Oct R.NLPFDLTWQK.L "sp|Q9P2K5|MYEF2_HUMAN,tr|A0A0A0MR39|A0A0A0MR39_HUMAN,tr|A0A0C4DGV1|A0A0C4DGV1_HUMAN,tr|A0A087WUT0|A0A087WUT0_HUMAN,tr|H0YKS1|H0YKS1_HUMAN,tr|H0YN19|H0YN19_HUMAN,tr|A0A0A0MQW0|A0A0A0MQW0_HUMAN" 7 1260.6503 -1 22005 23259 2 1260.650728 631.3324 Myelin expression factor 2 OS=Homo sapiens OX=9606 GN=MYEF2 PE=1 SV=3 5.84 3796.9 - 2.22E+06 - - - 0.3609 - 1.967 0.456 - 286.6 1 2 0 0.0005 10 0 0 0 0.00E+00 0.00E+00 - - - 4.2972 0.9945 221125_WJC_METTL3_EV_vs_WT_F02.23263.23263.2 2.54 13/22 R.LDELEELLTNNR.L "sp|O75306|NDUS2_HUMAN,tr|A0A7I2V4X8|A0A7I2V4X8_HUMAN,tr|A0A7I2YQG7|A0A7I2YQG7_HUMAN,tr|A0A7I2V596|A0A7I2V596_HUMAN,tr|A0A7I2V5G4|A0A7I2V5G4_HUMAN,tr|A0A7I2V410|A0A7I2V410_HUMAN,tr|A0A7I2V630|A0A7I2V630_HUMAN,tr|A0A7I2V2B9|A0A7I2V2B9_HUMAN,tr|A0A7I2V3J6|A0A7I2V3J6_HUMAN,tr|A0A7I2V5E2|A0A7I2V5E2_HUMAN,tr|A0A7I2V4W5|A0A7I2V4W5_HUMAN" 11 1457.7362 1.05 22009 23263 2 1457.727118 729.8754 "NADH dehydrogenase [ubiquinone] iron-sulfur protein 2, mitochondrial OS=Homo sapiens OX=9606 GN=NDUFS2 PE=1 SV=2" 4 3797.2 - 1.56E+06 - - - -6.222 - 2.884 0.408 - 830.4 1 2 0 -0.0091 12 0 0 0 8.30E+06 7.87E+06 - - - 4.8385 1 221125_WJC_METTL3_EV_vs_WT_F02.23264.23264.3 2.90E-07 15/48 R.SIQFVDWC[160.03]PTGFK[136.11].V "sp|P68366|TBA4A_HUMAN,sp|P68363|TBA1B_HUMAN" 2 1591.7585 0.51 22010 23264 3 1591.759368 531.5934 Tubulin alpha-4A chain OS=Homo sapiens OX=9606 GN=TUBA4A PE=1 SV=1 5.55 3797.3 - 1.46E+06 - - - 0.5767 - 2.89 0.543 - 344.9 1 2 0 0.0009 13 0 0 0 4.27E+06 8.39E+06 - - - 7.471 0.9998 221125_WJC_METTL3_EV_vs_WT_F02.23267.23267.2 3.00E-05 15/26 K.EELALLDGSNVVFK.L "sp|O15212|PFD6_HUMAN,tr|A2AB88|A2AB88_HUMAN" 2 1532.8086 1.84 22013 23267 2 1532.811588 767.4116 Prefoldin subunit 6 OS=Homo sapiens OX=9606 GN=PFDN6 PE=1 SV=1 4.14 3797.6 - 1.39E+06 - - - 1.9337 - 2.886 0.528 - 830.8 1 2 0 0.003 14 0 0 0 1.74E+07 9.44E+06 - - - 5.5996 0.9999 221125_WJC_METTL3_EV_vs_WT_F02.23268.23268.2 3.49E-05 26-Nov K.VELTITPDFQWDEK.V "sp|O75643|U520_HUMAN,tr|A0A494C1A5|A0A494C1A5_HUMAN" 2 1719.8356 -1 22014 23268 2 1719.833361 860.9251 U5 small nuclear ribonucleoprotein 200 kDa helicase OS=Homo sapiens OX=9606 GN=SNRNP200 PE=1 SV=2 3.92 3797.8 - 1.20E+06 - - - -1.2827 - 2.583 0.576 - 290.6 1 2 0 -0.0022 14 0 0 0 0.00E+00 0.00E+00 - - - 5.676 0.9999 221125_WJC_METTL3_EV_vs_WT_F02.23269.23269.2 0.00752 15/22 R.LDELEELLTNNR[166.11].L "sp|O75306|NDUS2_HUMAN,tr|A0A7I2V4X8|A0A7I2V4X8_HUMAN,tr|A0A7I2YQG7|A0A7I2YQG7_HUMAN,tr|A0A7I2V596|A0A7I2V596_HUMAN,tr|A0A7I2V5G4|A0A7I2V5G4_HUMAN,tr|A0A7I2V410|A0A7I2V410_HUMAN,tr|A0A7I2V630|A0A7I2V630_HUMAN,tr|A0A7I2V2B9|A0A7I2V2B9_HUMAN,tr|A0A7I2V3J6|A0A7I2V3J6_HUMAN,tr|A0A7I2V5E2|A0A7I2V5E2_HUMAN,tr|A0A7I2V4W5|A0A7I2V4W5_HUMAN" 11 1467.7445 -1 22015 23269 2 1467.74359 734.8795 "NADH dehydrogenase [ubiquinone] iron-sulfur protein 2, mitochondrial OS=Homo sapiens OX=9606 GN=NDUFS2 PE=1 SV=2" 4 3797.9 - 1.17E+06 - - - -0.5914 - 2.763 0.44 - 1174.4 1 2 0 -0.0009 12 0 0 0 0.00E+00 0.00E+00 - - - 4.9647 1 221125_WJC_METTL3_EV_vs_WT_F02.23272.23272.2 3.54E-09 18/36 R.NVPVLFNDTETNLAGMYGK.V "sp|Q8TBA6|GOGA5_HUMAN,tr|H0YK03|H0YK03_HUMAN" 2 2082.0092 -1 22017 23272 2 2082.014743 1042.0119 Golgin subfamily A member 5 OS=Homo sapiens OX=9606 GN=GOLGA5 PE=1 SV=3 4.37 3798.2 - 884648 - - - 2.6662 - 3.144 0.697 - 686.4 1 2 0 0.0056 19 0 0 0 0.00E+00 0.00E+00 - - - 7.0036 1 221125_WJC_METTL3_EV_vs_WT_F02.23273.23273.3 1.76E-11 16/56 R.HFYWYLTNEGIQYLR.D "sp|P46783|RS10_HUMAN,tr|A0A2R8Y6L3|A0A2R8Y6L3_HUMAN,tr|F6U211|F6U211_HUMAN,tr|A0A1W2PQS6|A0A1W2PQS6_HUMAN,tr|A0A2R8YFH6|A0A2R8YFH6_HUMAN,tr|A0A2R8Y7H1|A0A2R8Y7H1_HUMAN,tr|S4R435|S4R435_HUMAN" 7 2001.9737 1.1 22018 23273 3 2001.975182 668.3319 40S ribosomal protein S10 OS=Homo sapiens OX=9606 GN=RPS10 PE=1 SV=1 6.75 3798.3 - 1.85E+07 - - - 0.7238 - 3.32 0.643 - 481.6 1 2 0 0.0014 15 0 0 0 2.25E+08 2.04E+08 - - - 8.8396 0.9996 221125_WJC_METTL3_EV_vs_WT_F02.23274.23274.2 0.0224 22-Jul K.LFMAQALQEYNN.- "sp|O15372|EIF3H_HUMAN,tr|B3KS98|B3KS98_HUMAN,tr|A0A087WZK9|A0A087WZK9_HUMAN" 3 1440.6708 - 22019 23274 2 1440.668843 721.3427 Eukaryotic translation initiation factor 3 subunit H OS=Homo sapiens OX=9606 GN=EIF3H PE=1 SV=1 4 3798.3 - 1.32E+07 - - - -1.3244 - 1.583 0.447 - 140.1 1 2 0 -0.0019 12 0 0 0 - - - - - 3.5505 1 221125_WJC_METTL3_EV_vs_WT_F02.23275.23275.3 3.31E-08 20/68 K.AIEPPPLDAVIEAEHTLR[166.11].E sp|Q08211|DHX9_HUMAN 1 1980.0556 1.22 22020 23275 3 1980.053309 661.0258 ATP-dependent RNA helicase A OS=Homo sapiens OX=9606 GN=DHX9 PE=1 SV=4 4.4 3798.4 - 5.92E+06 - - - -1.1378 - 3.278 0.582 - 460.5 1 2 0 -0.0023 18 0 0 0 3.21E+08 2.62E+08 - - - 7.9844 0.9999 221125_WJC_METTL3_EV_vs_WT_F02.23276.23276.3 2.55E-05 Sep-44 R.EGDVLTLLESER.E sp|P62857|RS28_HUMAN 1 1359.6882 0.97 22021 23276 3 1359.687034 454.2367 40S ribosomal protein S28 OS=Homo sapiens OX=9606 GN=RPS28 PE=1 SV=1 4 3798.4 - 4.63E+06 - - - -0.8392 - 1.931 0.419 - 127.8 1 2 0 -0.0011 12 0 0 0 1.44E+07 1.48E+07 - - - 5.0351 1 221125_WJC_METTL3_EV_vs_WT_F02.23277.23277.3 4.46E-07 18/72 K.LGISPLMLAAMNGHVPAVK.L "sp|Q8IWZ3|ANKH1_HUMAN,tr|E9PDP5|E9PDP5_HUMAN,tr|H3BLS9|H3BLS9_HUMAN,tr|H7C2F5|H7C2F5_HUMAN" 4 1918.0532 1.15 22022 23277 3 1918.052351 640.3584 Ankyrin repeat and KH domain-containing protein 1 OS=Homo sapiens OX=9606 GN=ANKHD1 PE=1 SV=1 8.76 3798.4 - 4.35E+06 - - - -0.4661 - 3.347 0.532 - 319.4 1 2 0 -0.0009 19 0 0 0 1.35E+07 1.17E+07 - - - 7.439 0.9998 221125_WJC_METTL3_EV_vs_WT_F02.23279.23279.2 0.000297 20-Nov R.QLLEEMLTSYR.L sp|O75688|PPM1B_HUMAN 1 1381.6912 3.21 22024 23279 2 1381.688717 691.8529 Protein phosphatase 1B OS=Homo sapiens OX=9606 GN=PPM1B PE=1 SV=1 4.53 3798.6 - 3.76E+06 - - - -1.7623 - 2.458 0.522 - 637.2 1 2 0 -0.0024 11 0 0 0 6.35E+07 1.98E+07 - - - 5.3287 1 221125_WJC_METTL3_EV_vs_WT_F02.23280.23280.3 4.09E-10 20/72 K.LGISPLMLAAMNGHVPAVK[136.11].L "sp|Q8IWZ3|ANKH1_HUMAN,tr|E9PDP5|E9PDP5_HUMAN,tr|H3BLS9|H3BLS9_HUMAN,tr|H7C2F5|H7C2F5_HUMAN" 4 1926.0674 1.15 22025 23280 3 1926.063862 643.0298 Ankyrin repeat and KH domain-containing protein 1 OS=Homo sapiens OX=9606 GN=ANKHD1 PE=1 SV=1 8.76 3798.6 - 3.48E+06 - - - -1.8603 - 3.383 0.503 - 388 1 2 0 -0.0036 19 0 0 0 1.35E+07 1.17E+07 - - - 7.1412 1 221125_WJC_METTL3_EV_vs_WT_F02.23282.23282.3 8.35E-05 16/44 R.EGFLDTLVVLHR.A "sp|P42771|CDN2A_HUMAN,sp|P42772|CDN2B_HUMAN,tr|K7ENC6|K7ENC6_HUMAN,tr|J3QRG6|J3QRG6_HUMAN,tr|K7ES20|K7ES20_HUMAN" 5 1397.7667 2.16 22027 23282 3 1397.766403 466.9295 Cyclin-dependent kinase inhibitor 2A OS=Homo sapiens OX=9606 GN=CDKN2A PE=1 SV=2 5.32 3798.8 - 1.93E+06 - - - -0.2125 - 2.598 0.451 - 331.5 1 2 0 -0.0003 12 0 0 0 9.21E+07 4.27E+07 - - - 6.2145 0.9988 221125_WJC_METTL3_EV_vs_WT_F02.23283.23283.3 0.00306 15/44 R.LDELEELLTNNR[166.11].L "sp|O75306|NDUS2_HUMAN,tr|A0A7I2V4X8|A0A7I2V4X8_HUMAN,tr|A0A7I2YQG7|A0A7I2YQG7_HUMAN,tr|A0A7I2V596|A0A7I2V596_HUMAN,tr|A0A7I2V5G4|A0A7I2V5G4_HUMAN,tr|A0A7I2V410|A0A7I2V410_HUMAN,tr|A0A7I2V630|A0A7I2V630_HUMAN,tr|A0A7I2V2B9|A0A7I2V2B9_HUMAN,tr|A0A7I2V3J6|A0A7I2V3J6_HUMAN,tr|A0A7I2V5E2|A0A7I2V5E2_HUMAN,tr|A0A7I2V4W5|A0A7I2V4W5_HUMAN" 11 1467.7445 2.91 22028 23283 3 1467.739048 490.2554 "NADH dehydrogenase [ubiquinone] iron-sulfur protein 2, mitochondrial OS=Homo sapiens OX=9606 GN=NDUFS2 PE=1 SV=2" 4 3798.9 - 1.46E+06 - - - -3.6859 - 2.723 0.294 - 369.8 1 2 0 -0.0054 12 0 0 0 9.71E+06 3.33E+06 - - - 4.593 0.9883 221125_WJC_METTL3_EV_vs_WT_F02.23284.23284.2 0.000965 13/30 K.ITISSLQDLSIYNPER[166.11].T "sp|Q9Y6M1|IF2B2_HUMAN,tr|F8W930|F8W930_HUMAN" 2 1857.9712 1.31 22029 23284 2 1858.975874 929.9929 Insulin-like growth factor 2 mRNA-binding protein 2 OS=Homo sapiens OX=9606 GN=IGF2BP2 PE=1 SV=2 4.37 3799 - 1.46E+06 - - - 540.757 - 2.504 0.385 - 290.9 1 2 0 1.0047 16 0 0 0 7.31E+06 5.58E+06 - - - 3.8258 0.9991 221125_WJC_METTL3_EV_vs_WT_F02.23285.23285.3 0.000487 Oct-36 K.YR[166.11]PLFDYFLK[136.11].C "sp|P41252|SYIC_HUMAN,tr|A0A804HL54|A0A804HL54_HUMAN,tr|A0A804HKU1|A0A804HKU1_HUMAN,tr|A0A804HK69|A0A804HK69_HUMAN,tr|A0A804HIV9|A0A804HIV9_HUMAN,tr|A0A804HJN6|A0A804HJN6_HUMAN,tr|A0A804HHW9|A0A804HHW9_HUMAN,tr|A0A0A0MSX9|A0A0A0MSX9_HUMAN,tr|J3KR24|J3KR24_HUMAN,tr|A0A804HIG2|A0A804HIG2_HUMAN,tr|A0A804HJ36|A0A804HJ36_HUMAN" 11 1378.7404 0.05 22030 23285 3 1378.740367 460.5874 "Isoleucine--tRNA ligase, cytoplasmic OS=Homo sapiens OX=9606 GN=IARS1 PE=1 SV=2" 8.5 3799.1 - 1.39E+06 - - - -0.045 - 1.823 0.275 - 119 1 2 0 -0.0001 10 0 0 0 3.98E+05 7.74E+06 - - - 3.3596 1 221125_WJC_METTL3_EV_vs_WT_F02.23287.23287.2 4.89E-15 20/28 R.HFYWYLTNEGIQYLR[166.11].D "sp|P46783|RS10_HUMAN,tr|A0A2R8Y6L3|A0A2R8Y6L3_HUMAN,tr|F6U211|F6U211_HUMAN,tr|A0A1W2PQS6|A0A1W2PQS6_HUMAN,tr|A0A2R8YFH6|A0A2R8YFH6_HUMAN,tr|A0A2R8Y7H1|A0A2R8Y7H1_HUMAN,tr|S4R435|S4R435_HUMAN" 7 2011.982 1.39 22032 23287 2 2011.982796 1006.9983 40S ribosomal protein S10 OS=Homo sapiens OX=9606 GN=RPS10 PE=1 SV=1 6.75 3799.4 - 1.32E+06 - - - 0.3941 - 3.468 0.734 - 1074.9 1 2 0 0.0008 15 0 0 0 4.20E+07 3.03E+07 - - - 7.5195 0.9994 221125_WJC_METTL3_EV_vs_WT_F02.23289.23289.2 3.58E-05 22-Dec K.DLLNMYIETEGK.M "sp|Q92598|HS105_HUMAN,tr|A0A0A0MSM0|A0A0A0MSM0_HUMAN" 2 1424.6857 0.11 22034 23289 2 1424.682332 713.3501 Heat shock protein 105 kDa OS=Homo sapiens OX=9606 GN=HSPH1 PE=1 SV=1 4.14 3799.5 - 1.16E+06 - - - -2.3865 - 1.699 0.493 - 370.1 1 2 0 -0.0034 12 0 0 0 5.43E+06 4.90E+07 - - - 4.0759 1 221125_WJC_METTL3_EV_vs_WT_F02.23292.23292.2 1.93E-05 13/22 K.DLLNMYIETEGK[136.11].M "sp|Q92598|HS105_HUMAN,tr|A0A0A0MSM0|A0A0A0MSM0_HUMAN" 2 1432.6999 0.07 22036 23292 2 1432.69955 717.3572 Heat shock protein 105 kDa OS=Homo sapiens OX=9606 GN=HSPH1 PE=1 SV=1 4.14 3799.9 - 4.08E+06 - - - -0.2666 - 2.65 0.565 - 492.7 1 2 0 -0.0004 12 0 0 0 1.26E+07 1.83E+08 - - - 5.7782 0.9998 221125_WJC_METTL3_EV_vs_WT_F02.23293.23293.3 0.000158 Dec-48 R.SIQFVDWC[160.03]PTGFK.V "sp|P68366|TBA4A_HUMAN,sp|P68363|TBA1B_HUMAN" 2 1583.7442 -1 22037 23293 3 1583.740611 528.922 Tubulin alpha-4A chain OS=Homo sapiens OX=9606 GN=TUBA4A PE=1 SV=1 5.55 3800 - 1.02E+06 - - - -2.2977 - 1.907 0.464 - 143.1 1 2 0 -0.0036 13 0 0 0 0.00E+00 0.00E+00 - - - 5.4624 0.9999 221125_WJC_METTL3_EV_vs_WT_F02.23294.23294.2 0.000987 24-Nov K.DFLAGGIAAAISK.T sp|P12236|ADT3_HUMAN 1 1232.6765 0.99 22038 23294 2 1232.676066 617.3455 ADP\ATP translocase 3 OS=Homo sapiens OX=9606 GN=SLC25A6 PE=1 SV=4 5.84 3800 - 9.72E+06 - - - -0.3423 - 2.458 0.505 - 321.5 1 2 0 -0.0004 13 0 0 0 3.64E+07 3.68E+07 - - - 5.079 0.9998 221125_WJC_METTL3_EV_vs_WT_F02.23296.23296.2 1.04E-07 13/20 R.QLLEEMLTSYR[166.11].L sp|O75688|PPM1B_HUMAN 1 1391.6994 3.21 22040 23296 2 1391.698167 696.857 Protein phosphatase 1B OS=Homo sapiens OX=9606 GN=PPM1B PE=1 SV=1 4.53 3800.1 - 4.28E+06 - - - -0.9018 - 2.562 0.414 - 941.4 1 2 0 -0.0013 11 0 0 0 6.35E+07 1.98E+07 - - - 4.6435 1 221125_WJC_METTL3_EV_vs_WT_F02.23297.23297.3 2.60E-05 18/44 R.EGFLDTLVVLHR[166.11].A "sp|P42771|CDN2A_HUMAN,sp|P42772|CDN2B_HUMAN,tr|K7ENC6|K7ENC6_HUMAN,tr|J3QRG6|J3QRG6_HUMAN,tr|K7ES20|K7ES20_HUMAN" 5 1407.775 2.17 22041 23297 3 1407.774112 470.2656 Cyclin-dependent kinase inhibitor 2A OS=Homo sapiens OX=9606 GN=CDKN2A PE=1 SV=2 5.32 3800.2 - 2.78E+06 - - - -0.6095 - 2.828 0.493 - 475.5 1 2 0 -0.0009 12 0 0 0 9.20E+07 4.25E+07 - - - 6.9178 1 221125_WJC_METTL3_EV_vs_WT_F02.23299.23299.2 3.18E-13 19/28 R.HFYWYLTNEGIQYLR.D "sp|P46783|RS10_HUMAN,tr|A0A2R8Y6L3|A0A2R8Y6L3_HUMAN,tr|F6U211|F6U211_HUMAN,tr|A0A1W2PQS6|A0A1W2PQS6_HUMAN,tr|A0A2R8YFH6|A0A2R8YFH6_HUMAN,tr|A0A2R8Y7H1|A0A2R8Y7H1_HUMAN,tr|S4R435|S4R435_HUMAN" 7 2001.9737 1.48 22043 23299 2 2001.958943 1001.9941 40S ribosomal protein S10 OS=Homo sapiens OX=9606 GN=RPS10 PE=1 SV=1 6.75 3800.4 - 1.41E+06 - - - -7.3877 - 3.498 0.62 - 988.8 1 2 0 -0.0148 15 0 0 0 4.10E+07 2.76E+07 - - - 6.6942 1 221125_WJC_METTL3_EV_vs_WT_F02.23301.23301.2 5.75E-12 16/34 R.FASWALESDNNTALLLSK[136.11].K sp|Q13263|TIF1B_HUMAN 1 1987.0142 0.84 22045 23301 2 1987.008578 994.5144 Transcription intermediary factor 1-beta OS=Homo sapiens OX=9606 GN=TRIM28 PE=1 SV=5 4.37 3800.7 - 1.12E+06 - - - -2.8329 - 3.467 0.611 - 791.2 1 2 0 -0.0056 18 0 0 0 5.97E+06 7.09E+06 - - - 6.6088 1 221125_WJC_METTL3_EV_vs_WT_F02.23308.23308.2 6.45E-07 18/30 R.QLLQANPILESFGNAK.T sp|P35580|MYH10_HUMAN 1 1741.9363 1.25 22052 23308 2 1741.940787 871.9754 Myosin-10 OS=Homo sapiens OX=9606 GN=MYH10 PE=1 SV=3 6 3801.6 - 811498 - - - 2.5845 - 2.987 0.556 - 758 1 2 0 0.0045 16 0 0 0 1.36E+08 1.08E+08 - - - 5.8365 0.9992 221125_WJC_METTL3_EV_vs_WT_F02.23311.23311.3 0.000586 Sep-48 K.DFLAGGIAAAISK[136.11].T sp|P12236|ADT3_HUMAN 1 1240.6907 -1 22055 23311 3 1240.688253 414.5708 ADP\ATP translocase 3 OS=Homo sapiens OX=9606 GN=SLC25A6 PE=1 SV=4 5.84 3802 - 675942 - - - -1.9626 - 1.918 0.326 - 74.8 1 2 0 -0.0024 13 0 0 0 0.00E+00 0.00E+00 - - - 3.9397 0.9328 221125_WJC_METTL3_EV_vs_WT_F02.23319.23319.2 2.19E-06 17/28 K.VSQEILELLNTTTAK.E "sp|Q86U44|MTA70_HUMAN,tr|H0YFV6|H0YFV6_HUMAN" 2 1658.9091 0.03 22062 23319 2 1659.90387 830.4618 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 4.53 3802.7 - 1.82E+06 - - - 599.673 - 3.476 0.531 - 1324.8 1 2 0 0.9948 15 0 0 0 2.96E+09 1.03E+11 - - - 5.7137 1 221125_WJC_METTL3_EV_vs_WT_F02.23320.23320.2 1.75E-06 20/30 R.QLLQANPILESFGNAK[136.11].T sp|P35580|MYH10_HUMAN 1 1749.9505 1.25 22063 23320 2 1749.947634 875.9825 Myosin-10 OS=Homo sapiens OX=9606 GN=MYH10 PE=1 SV=3 6 3802.8 - 1.80E+06 - - - -1.6292 - 3.677 0.548 - 1393.6 1 2 0 -0.0029 16 0 0 0 1.36E+08 1.08E+08 - - - 6.2889 1 221125_WJC_METTL3_EV_vs_WT_F02.23321.23321.3 2.67E-16 30/112 K.SPLPTPGAPVPVPAATGPYYSPYALYGQR.L sp|Q96F45|ZN503_HUMAN 1 2986.5229 8.75 22064 23321 3 2986.52429 996.5149 Zinc finger protein 503 OS=Homo sapiens OX=9606 GN=ZNF503 PE=1 SV=1 8.15 3802.9 - 1.42E+06 - - - 0.4671 - 5.229 0.721 - 798.8 1 2 0 0.0014 29 0 0 0 1.39E+07 1.59E+06 - - - 10.3838 0.9798 221125_WJC_METTL3_EV_vs_WT_F02.23322.23322.2 1.13 16-Sep K.LLEVLSGER[166.11].L "sp|Q01082|SPTB2_HUMAN,sp|O43707|ACTN4_HUMAN,sp|Q08043|ACTN3_HUMAN,sp|P35609|ACTN2_HUMAN,sp|P12814|ACTN1_HUMAN,tr|A0A804HJN7|A0A804HJN7_HUMAN,tr|A0A804HK61|A0A804HK61_HUMAN,tr|G3V2E8|G3V2E8_HUMAN,tr|G3V2W4|G3V2W4_HUMAN,tr|A0A494C033|A0A494C033_HUMAN,tr|A0A804HIN7|A0A804HIN7_HUMAN,tr|G3V5M4|G3V5M4_HUMAN,tr|H9KV75|H9KV75_HUMAN,tr|A0A087WSZ2|A0A087WSZ2_HUMAN,tr|A0A804HLF4|A0A804HLF4_HUMAN,tr|A0A804HKG0|A0A804HKG0_HUMAN,tr|A0A804HIY0|A0A804HIY0_HUMAN,tr|A0A087WUZ3|A0A087WUZ3_HUMAN,tr|A0A7I2V4Y4|A0A7I2V4Y4_HUMAN,tr|A0A804HII9|A0A804HII9_HUMAN,tr|A0A804HL31|A0A804HL31_HUMAN,tr|F8W6C1|F8W6C1_HUMAN,tr|A0A494C1A0|A0A494C1A0_HUMAN,tr|A0A804HJQ9|A0A804HJQ9_HUMAN,tr|F5GXS2|F5GXS2_HUMAN,tr|A0A494C166|A0A494C166_HUMAN,tr|A0A804HI95|A0A804HI95_HUMAN,tr|A0A494C0Q3|A0A494C0Q3_HUMAN,tr|G3V2X9|G3V2X9_HUMAN,tr|A0A804HKE2|A0A804HKE2_HUMAN,tr|G3V2N5|G3V2N5_HUMAN,tr|A0A494C031|A0A494C031_HUMAN,tr|A0A804HLD0|A0A804HLD0_HUMAN,tr|H7C144|H7C144_HUMAN" 34 1024.5792 0.001 22065 23322 2 1024.581833 513.2969 "Spectrin beta chain, non-erythrocytic 1 OS=Homo sapiens OX=9606 GN=SPTBN1 PE=1 SV=2" 4.53 3803.1 - 1.35E+06 - - - 2.5406 - 1.406 0.144 - 78.2 2 2 0 0.0026 9 0 0 0 0.00E+00 4.93E+08 - - - 0.9551 0.9999 221125_WJC_METTL3_EV_vs_WT_F02.23323.23323.2 1.75 15/22 R.EGFLDTLVVLHR.A "sp|P42771|CDN2A_HUMAN,sp|P42772|CDN2B_HUMAN,tr|K7ENC6|K7ENC6_HUMAN,tr|J3QRG6|J3QRG6_HUMAN,tr|K7ES20|K7ES20_HUMAN" 5 1397.7667 7.07 22066 23323 2 1397.766446 699.8906 Cyclin-dependent kinase inhibitor 2A OS=Homo sapiens OX=9606 GN=CDKN2A PE=1 SV=2 5.32 3803.2 - 1.30E+06 - - - -0.1817 - 2.936 0.501 - 822.3 1 2 0 -0.0003 12 0 0 0 2.74E+07 3.87E+06 - - - 5.5752 0.9996 221125_WJC_METTL3_EV_vs_WT_F02.23324.23324.2 7.00E-09 18/34 R.TVAAPSVFIFPPSDEQLK.S "sp|P01834|IGKC_HUMAN,tr|A0A5H1ZRQ3|A0A5H1ZRQ3_HUMAN" 2 1945.0197 999 22067 23324 2 1945.01401 973.5171 Immunoglobulin kappa constant OS=Homo sapiens OX=9606 GN=IGKC PE=1 SV=2 4.37 3803.3 - 1.22E+06 - - - -2.9151 - 3.035 0.489 - 606.6 1 2 0 -0.0057 18 0 0 0 1.16E+07 0.00E+00 - - - 5.3805 1 221125_WJC_METTL3_EV_vs_WT_F02.23326.23326.2 3.97E-06 16/34 R.FASWALESDNNTALLLSK.K sp|Q13263|TIF1B_HUMAN 1 1979 0.64 22069 23326 2 1979.002233 990.5073 Transcription intermediary factor 1-beta OS=Homo sapiens OX=9606 GN=TRIM28 PE=1 SV=5 4.37 3803.6 - 976623 - - - 1.1248 - 3.208 0.541 - 683.6 1 2 0 0.0022 18 0 0 0 5.97E+06 9.32E+06 - - - 5.9019 0.9879 221125_WJC_METTL3_EV_vs_WT_F02.23330.23330.3 0.000322 17/64 K.IELFGR[166.11]PHNVQPNWITL.G sp|Q86U44|MTA70_HUMAN 1 2043.0929 0.01 22071 23330 3 2043.086763 682.0383 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 6.75 3804.1 - 4.73E+07 - - - -3.0283 - 3.019 0.463 - 335.9 1 1 0 -0.0062 17 0 0 0 1.59E+07 1.46E+09 - - - 6.4917 0.9559 221125_WJC_METTL3_EV_vs_WT_F02.23337.23337.2 0.656 16-Nov L.ELLNTTTAK[136.11].E "sp|Q86U44|MTA70_HUMAN,tr|H0YFV6|H0YFV6_HUMAN" 2 997.5535 0.001 22078 23337 2 997.552631 499.784 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 6.1 3804.6 - 2.21E+06 - - - -0.8972 - 2.121 0.206 - 324.9 1 1 0 -0.0009 9 0 0 0 0.00E+00 1.19E+08 - - - 2.7375 0.9903 221125_WJC_METTL3_EV_vs_WT_F02.23339.23339.3 0.0154 16/68 R.TVAAPSVFIFPPSDEQLK.S "sp|P01834|IGKC_HUMAN,tr|A0A5H1ZRQ3|A0A5H1ZRQ3_HUMAN" 2 1945.0197 999 22080 23339 3 1945.012744 649.3472 Immunoglobulin kappa constant OS=Homo sapiens OX=9606 GN=IGKC PE=1 SV=2 4.37 3804.9 - 1.40E+06 - - - -3.566 - 2.041 0.235 - 233.3 1 2 0 -0.0069 18 0 0 0 1.19E+07 0.00E+00 - - - 2.9346 1 221125_WJC_METTL3_EV_vs_WT_F02.23342.23342.2 4.03E-07 17/32 K.IELFGR[166.11]PHNVQPNWITL.G sp|Q86U44|MTA70_HUMAN 1 2043.0929 0.001 22081 23342 2 2043.087663 1022.5538 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 6.75 3805.3 - 3.03E+06 - - - -2.5877 - 2.634 0.605 - 502.8 1 1 0 -0.0053 17 0 0 0 0.00E+00 3.45E+08 - - - 5.889 1 221125_WJC_METTL3_EV_vs_WT_F02.23343.23343.3 3.26E-06 25/68 K.AIEPPPLDAVIEAEHTLR.E sp|Q08211|DHX9_HUMAN 1 1970.0473 1.24 22082 23343 3 1970.044662 657.6897 ATP-dependent RNA helicase A OS=Homo sapiens OX=9606 GN=DHX9 PE=1 SV=4 4.4 3805.3 - 4.69E+06 - - - -1.335 - 3.744 0.592 - 823 1 2 0 -0.0026 18 0 0 0 3.25E+08 2.62E+08 - - - 8.4268 0.9986 221125_WJC_METTL3_EV_vs_WT_F02.23350.23350.2 1.59E-05 26-Sep R.NPPGFAFVEFEDPR.D "sp|Q16629|SRSF7_HUMAN,sp|P84103|SRSF3_HUMAN,tr|A0A087X2D0|A0A087X2D0_HUMAN,tr|C9JAB2|C9JAB2_HUMAN,tr|A0A0B4J1Z1|A0A0B4J1Z1_HUMAN" 5 1620.7573 1.22 22086 23350 2 1620.750666 811.3859 Serine\arginine-rich splicing factor 7 OS=Homo sapiens OX=9606 GN=SRSF7 PE=1 SV=1 4.14 3806.1 - 9.94E+06 - - - -4.0672 - 1.713 0.561 - 113.5 1 2 0 -0.0066 14 0 0 0 4.39E+08 3.59E+08 - - - 4.5332 0.796 221125_WJC_METTL3_EV_vs_WT_F02.23359.23359.2 0.00242 22-Oct K.HSQFLGYPITLY.L "sp|Q58FF8|H90B2_HUMAN,sp|P08238|HS90B_HUMAN,sp|Q58FF7|H90B3_HUMAN" 3 1437.7293 - 22093 23359 2 1437.726942 719.8719 Putative heat shock protein HSP 90-beta 2 OS=Homo sapiens OX=9606 GN=HSP90AB2P PE=1 SV=2 6.74 3807.1 - 0 - - - -1.6067 - 1.846 0.146 - 271.4 2 1 0 -0.0023 12 0 0 0 - - - - - 1.5971 1 221125_WJC_METTL3_EV_vs_WT_F02.23367.23367.2 6.13E-09 14/26 R.NPPGFAFVEFEDPR[166.11].D "sp|Q16629|SRSF7_HUMAN,sp|P84103|SRSF3_HUMAN,tr|A0A087X2D0|A0A087X2D0_HUMAN,tr|C9JAB2|C9JAB2_HUMAN,tr|A0A0B4J1Z1|A0A0B4J1Z1_HUMAN" 5 1630.7655 1.2 22097 23367 2 1630.759119 816.39 Serine\arginine-rich splicing factor 7 OS=Homo sapiens OX=9606 GN=SRSF7 PE=1 SV=1 4.14 3808.1 - 7.52E+06 - - - -3.9301 - 2.427 0.646 - 288 1 2 0 -0.0064 14 0 0 0 4.39E+08 3.65E+08 - - - 6.0354 0.9998 221125_WJC_METTL3_EV_vs_WT_F02.23375.23375.2 9.70E-06 17/26 K.QATLIPDEVFDAVK.S sp|Q9H9A6|LRC40_HUMAN 1 1544.8086 1.07 22101 23375 2 1544.80636 773.4116 Leucine-rich repeat-containing protein 40 OS=Homo sapiens OX=9606 GN=LRRC40 PE=1 SV=1 4.03 3809 - 2.03E+06 - - - -1.4656 - 3.087 0.428 - 895.3 1 2 0 -0.0023 14 0 0 0 2.57E+07 2.40E+07 - - - 5.0301 1 221125_WJC_METTL3_EV_vs_WT_F02.23385.23385.2 5.98E-08 24-Dec K.QTVFYMEDYLTVK.T "sp|Q99873|ANM1_HUMAN,tr|E9PKG1|E9PKG1_HUMAN" 2 1635.7854 3.1 22106 23385 2 1635.782511 818.9 Protein arginine N-methyltransferase 1 OS=Homo sapiens OX=9606 GN=PRMT1 PE=1 SV=3 4.37 3810.1 - 6.48E+06 - - - -1.7942 - 2.516 0.655 - 432.6 1 2 0 -0.0029 13 0 0 0 2.13E+08 6.89E+07 - - - 6.246 0.8419 221125_WJC_METTL3_EV_vs_WT_F02.23386.23386.2 0.333 15/24 S.QEILELLNTTTAK[136.11].E "sp|Q86U44|MTA70_HUMAN,tr|H0YFV6|H0YFV6_HUMAN" 2 1480.8228 0.02 22107 23386 2 1480.814332 741.4187 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 4.53 3810.2 - 3.94E+06 - - - -5.7346 - 3.339 0.429 - 1074.9 1 1 0 -0.0085 13 0 0 0 1.94E+06 9.32E+07 - - - 5.3013 1 221125_WJC_METTL3_EV_vs_WT_F02.23393.23393.2 5.48E-08 19/34 K.LVLPAPQISDAELQEVVK[136.11].V sp|Q99459|CDC5L_HUMAN 1 1956.1023 1.56 22111 23393 2 1956.100101 979.0584 Cell division cycle 5-like protein OS=Homo sapiens OX=9606 GN=CDC5L PE=1 SV=2 4.14 3811.2 - 2.41E+06 - - - -1.1211 - 2.972 0.582 - 967.5 1 2 0 -0.0022 18 0 0 0 5.36E+07 3.44E+07 - - - 6.0169 0.9857 221125_WJC_METTL3_EV_vs_WT_F02.23394.23394.3 7.44E-08 13/56 K.VSQEILELLNTTTAK[136.11].E "sp|Q86U44|MTA70_HUMAN,tr|H0YFV6|H0YFV6_HUMAN" 2 1666.9233 0.03 22112 23394 3 1667.917103 556.6484 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 4.53 3811.2 - 2.07E+09 - - - 596.2098 - 2.957 0.542 - 268.7 1 2 0 0.9938 15 0 0 0 1.39E+09 5.33E+10 - - - 7.1365 0.9997 221125_WJC_METTL3_EV_vs_WT_F02.23396.23396.2 3.82E-05 15/22 K.LEDILESINSIK[136.11].S sp|Q9Y3A6|TMED5_HUMAN 1 1380.7592 1.68 22114 23396 2 1380.755826 691.3869 Transmembrane emp24 domain-containing protein 5 OS=Homo sapiens OX=9606 GN=TMED5 PE=1 SV=1 4.14 3811.4 - 2.56E+06 - - - -2.4153 - 2.89 0.504 - 937.9 1 2 0 -0.0033 12 0 0 0 3.30E+07 1.97E+07 - - - 5.5548 1 221125_WJC_METTL3_EV_vs_WT_F02.23399.23399.2 4.94E-08 17/34 K.LVLPAPQISDAELQEVVK.V sp|Q99459|CDC5L_HUMAN 1 1948.0881 1.56 22115 23399 2 1948.089546 975.0513 Cell division cycle 5-like protein OS=Homo sapiens OX=9606 GN=CDC5L PE=1 SV=2 4.14 3811.8 - 0 - - - 0.7453 - 2.898 0.655 - 684.1 1 2 0 0.0015 18 0 0 0 5.36E+07 3.44E+07 - - - 6.4943 0.9998 221125_WJC_METTL3_EV_vs_WT_F02.23401.23401.2 3.37E-09 15/24 R.TIQFVDWC[160.03]PTGFK[136.11].V "sp|Q9NY65|TBA8_HUMAN,sp|Q6PEY2|TBA3E_HUMAN,sp|P0DPH7|TBA3C_HUMAN,sp|Q71U36|TBA1A_HUMAN,sp|P0DPH8|TBA3D_HUMAN,sp|Q9BQE3|TBA1C_HUMAN,tr|A0A7P0TA31|A0A7P0TA31_HUMAN,tr|A0A1W2PQM2|A0A1W2PQM2_HUMAN,tr|F5H5D3|F5H5D3_HUMAN,tr|C9J2C0|C9J2C0_HUMAN,tr|V9GZ17|V9GZ17_HUMAN,tr|A0A7P0T945|A0A7P0T945_HUMAN" 12 1605.7741 0.51 22116 23401 2 1605.771509 803.8943 Tubulin alpha-8 chain OS=Homo sapiens OX=9606 GN=TUBA8 PE=1 SV=1 5.5 3812 - 7.80E+06 - - - -1.6136 - 2.517 0.469 - 680.3 1 2 0 -0.0026 13 0 0 0 7.85E+07 1.53E+08 - - - 4.8733 1 221125_WJC_METTL3_EV_vs_WT_F02.23402.23402.2 6.26E-07 24-Dec K.QTVFYMEDYLTVK[136.11].T "sp|Q99873|ANM1_HUMAN,tr|E9PKG1|E9PKG1_HUMAN" 2 1643.7996 3.1 22117 23402 2 1643.800916 822.9071 Protein arginine N-methyltransferase 1 OS=Homo sapiens OX=9606 GN=PRMT1 PE=1 SV=3 4.37 3812.1 - 3.73E+06 - - - 0.7726 - 2.68 0.595 - 402.3 1 2 0 0.0013 13 0 0 0 2.13E+08 6.89E+07 - - - 5.9654 1 221125_WJC_METTL3_EV_vs_WT_F02.23407.23407.3 6.71E-10 22/68 K.LVLPAPQISDAELQEVVK.V sp|Q99459|CDC5L_HUMAN 1 1948.0881 1.4 22120 23407 3 1948.078243 650.37 Cell division cycle 5-like protein OS=Homo sapiens OX=9606 GN=CDC5L PE=1 SV=2 4.14 3812.7 - 1.98E+06 - - - -5.0568 - 3.885 0.633 - 559.9 1 2 0 -0.0099 18 0 0 0 3.10E+07 2.22E+07 - - - 8.974 1 221125_WJC_METTL3_EV_vs_WT_F02.23408.23408.3 5.83E-06 17/72 R.AIAELGIYPAVDPLDSTSR.L "sp|P06576|ATPB_HUMAN,tr|H0YH81|H0YH81_HUMAN" 2 1987.0262 1.82 22121 23408 3 1987.023596 663.3494 "ATP synthase subunit beta, mitochondrial OS=Homo sapiens OX=9606 GN=ATP5F1B PE=1 SV=3" 4.03 3812.8 - 4.27E+06 - - - -1.3216 - 3.151 0.543 - 261.4 1 2 0 -0.0026 19 0 0 0 9.80E+07 5.38E+07 - - - 7.4129 1 221125_WJC_METTL3_EV_vs_WT_F02.23409.23409.3 3.23E-06 15/84 R.LAPITSDPTEATAVGAVEASFK.C "sp|P14618|KPYM_HUMAN,tr|B4DNK4|B4DNK4_HUMAN" 2 2174.1107 0.62 22122 23409 3 2174.108333 725.7108 Pyruvate kinase PKM OS=Homo sapiens OX=9606 GN=PKM PE=1 SV=4 4.14 3812.8 - 5.13E+06 - - - -1.0795 - 2.89 0.542 - 194.1 1 2 0 -0.0023 22 0 0 0 6.22E+07 1.00E+08 - - - 7.0982 1 221125_WJC_METTL3_EV_vs_WT_F02.23412.23412.2 1.14E-10 20/42 R.LAPITSDPTEATAVGAVEASFK.C "sp|P14618|KPYM_HUMAN,tr|B4DNK4|B4DNK4_HUMAN" 2 2174.1107 1.6 22125 23412 2 2174.116785 1088.0626 Pyruvate kinase PKM OS=Homo sapiens OX=9606 GN=PKM PE=1 SV=4 4.14 3813.2 - 1.48E+06 - - - 2.808 - 3.717 0.694 - 941.5 1 2 0 0.0061 22 0 0 0 3.09E+07 1.93E+07 - - - 7.3928 1 221125_WJC_METTL3_EV_vs_WT_F02.23413.23413.2 4.31E-05 18/26 R.DISEVIALGVPNPR[166.11].T "sp|Q13573|SNW1_HUMAN,tr|G3V4X8|G3V4X8_HUMAN,tr|G3V3A4|G3V3A4_HUMAN" 3 1488.8176 4.39 22126 23413 2 1488.819532 745.4161 SNW domain-containing protein 1 OS=Homo sapiens OX=9606 GN=SNW1 PE=1 SV=1 4.37 3813.3 - 1.28E+06 - - - 1.3225 - 3.483 0.525 - 1342.4 1 2 0 0.002 14 0 0 0 1.19E+08 2.72E+07 - - - 6.0496 1 221125_WJC_METTL3_EV_vs_WT_F02.23416.23416.3 1.99E-07 13/56 R.DYLHLPPEIVPATLR[166.11].R "sp|P46783|RS10_HUMAN,tr|A0A2R8Y6L3|A0A2R8Y6L3_HUMAN,tr|F6U211|F6U211_HUMAN,tr|A0A1W2PQS6|A0A1W2PQS6_HUMAN,tr|A0A2R8YFH6|A0A2R8YFH6_HUMAN,tr|A0A2R8Y7H1|A0A2R8Y7H1_HUMAN,tr|S4R435|S4R435_HUMAN" 7 1742.9595 1.27 22128 23416 3 1742.958043 581.9938 40S ribosomal protein S10 OS=Homo sapiens OX=9606 GN=RPS10 PE=1 SV=1 5.32 3813.7 - 8.24E+06 - - - -0.8222 - 2.602 0.485 - 189.9 1 2 0 -0.0014 15 0 0 0 4.06E+08 3.19E+08 - - - 6.4422 0.9993 221125_WJC_METTL3_EV_vs_WT_F02.23420.23420.2 1.72E-06 19/36 R.AIAELGIYPAVDPLDSTSR[166.11].L "sp|P06576|ATPB_HUMAN,tr|H0YH81|H0YH81_HUMAN" 2 1997.0345 2.89 22131 23420 2 1997.026944 999.5245 "ATP synthase subunit beta, mitochondrial OS=Homo sapiens OX=9606 GN=ATP5F1B PE=1 SV=3" 4.03 3814 - 4.48E+06 - - - -3.7796 - 3.362 0.492 - 822.5 1 2 0 -0.0075 19 0 0 0 1.62E+08 5.61E+07 - - - 5.6536 0.9999 221125_WJC_METTL3_EV_vs_WT_F02.23421.23421.3 1.04E-05 16/84 R.LAPITSDPTEATAVGAVEASFK[136.11].C "sp|P14618|KPYM_HUMAN,tr|B4DNK4|B4DNK4_HUMAN" 2 2182.1249 1.14 22132 23421 3 2182.118469 728.3822 Pyruvate kinase PKM OS=Homo sapiens OX=9606 GN=PKM PE=1 SV=4 4.14 3814.1 - 3.18E+06 - - - -2.938 - 2.944 0.523 - 226.6 1 2 0 -0.0064 22 0 0 0 5.36E+07 4.70E+07 - - - 6.9291 0.9971 221125_WJC_METTL3_EV_vs_WT_F02.23425.23425.2 8.27E-06 17/28 R.GDINILLIGDPSVAK[136.11].S "sp|P25205|MCM3_HUMAN,tr|J3KQ69|J3KQ69_HUMAN,tr|A0A499FHX9|A0A499FHX9_HUMAN" 3 1531.8701 0.54 22136 23425 2 1531.861762 766.9423 DNA replication licensing factor MCM3 OS=Homo sapiens OX=9606 GN=MCM3 PE=1 SV=3 4.21 3814.5 - 1.69E+06 - - - -5.4489 - 2.942 0.453 - 846.9 1 2 0 -0.0083 15 0 0 0 6.83E+06 1.27E+07 - - - 5.0372 1 221125_WJC_METTL3_EV_vs_WT_F02.23426.23426.2 7.69E-14 20/42 R.LAPITSDPTEATAVGAVEASFK[136.11].C "sp|P14618|KPYM_HUMAN,tr|B4DNK4|B4DNK4_HUMAN" 2 2182.1249 2.04 22137 23426 2 2182.114996 1092.0697 Pyruvate kinase PKM OS=Homo sapiens OX=9606 GN=PKM PE=1 SV=4 4.14 3814.6 - 1.42E+06 - - - -4.5295 - 3.692 0.721 - 843.3 1 2 0 -0.0099 22 0 0 0 3.09E+07 1.51E+07 - - - 7.5745 0.9987 221125_WJC_METTL3_EV_vs_WT_F02.23427.23427.2 1.74E-05 28-Nov R.LSLFSDLPEDTELQR[166.11].K sp|Q9BST9|RTKN_HUMAN 1 1771.8868 -1 22138 23427 2 1771.880248 886.9507 Rhotekin OS=Homo sapiens OX=9606 GN=RTKN PE=1 SV=2 3.92 3814.8 - 754801 - - - -3.678 - 1.994 0.472 - 224.5 1 2 0 -0.0065 15 0 0 0 0.00E+00 0.00E+00 - - - 4.2219 1 221125_WJC_METTL3_EV_vs_WT_F02.23431.23431.3 8.46E-09 14/52 K.SNYNFEK[136.11]PFLWLAR[166.11].K "sp|P62826|RAN_HUMAN,tr|B5MDF5|B5MDF5_HUMAN,tr|J3KQE5|J3KQE5_HUMAN,tr|B4DV51|B4DV51_HUMAN,tr|F5H018|F5H018_HUMAN" 5 1801.9271 0.99 22140 23431 3 1801.922056 601.6496 GTP-binding nuclear protein Ran OS=Homo sapiens OX=9606 GN=RAN PE=1 SV=3 8.31 3815.2 - 3.36E+06 - - - -2.777 - 2.71 0.658 - 236.2 1 2 0 -0.005 14 0 0 0 4.23E+07 4.27E+07 - - - 8.5241 1 221125_WJC_METTL3_EV_vs_WT_F02.23432.23432.3 3.75E-09 Dec-52 K.SNYNFEKPFLWLAR.K "sp|P62826|RAN_HUMAN,tr|B5MDF5|B5MDF5_HUMAN,tr|J3KQE5|J3KQE5_HUMAN,tr|B4DV51|B4DV51_HUMAN,tr|F5H018|F5H018_HUMAN" 5 1783.9046 0.99 22141 23432 3 1783.901756 595.6421 GTP-binding nuclear protein Ran OS=Homo sapiens OX=9606 GN=RAN PE=1 SV=3 8.31 3815.2 - 3.20E+06 - - - -1.5886 - 2.511 0.622 - 200.2 1 2 0 -0.0028 14 0 0 0 4.23E+07 4.27E+07 - - - 7.9206 1 221125_WJC_METTL3_EV_vs_WT_F02.23434.23434.2 4.53E-08 20/32 K.WFGSDVLQQPLPSMPAK.V "sp|Q9NRA8|4ET_HUMAN,tr|B1AKL4|B1AKL4_HUMAN" 2 1899.9553 1.21 22143 23434 2 1899.950797 950.9849 Eukaryotic translation initiation factor 4E transporter OS=Homo sapiens OX=9606 GN=EIF4ENIF1 PE=1 SV=2 5.84 3815.5 - 887058 - - - -2.3727 - 3.353 0.653 - 1039.6 1 2 0 -0.0045 17 0 0 0 2.33E+07 1.93E+07 - - - 6.8371 1 221125_WJC_METTL3_EV_vs_WT_F02.23435.23435.3 9.26E-11 18/68 K.LVLPAPQISDAELQEVVK[136.11].V sp|Q99459|CDC5L_HUMAN 1 1956.1023 1.41 22144 23435 3 1956.107049 653.0414 Cell division cycle 5-like protein OS=Homo sapiens OX=9606 GN=CDC5L PE=1 SV=2 4.14 3815.6 - 833675 - - - 2.4309 - 3.457 0.641 - 371.9 1 2 0 0.0048 18 0 0 0 3.13E+07 2.22E+07 - - - 8.7739 0.9998 221125_WJC_METTL3_EV_vs_WT_F02.23440.23440.2 4.69E-06 22-Sep R.LFPPQWIC[160.03]C[160.03]DIR[166.11].Y sp|Q86U44|MTA70_HUMAN 1 1613.7722 0.05 22148 23440 2 1613.770602 807.8934 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 5.82 3816.1 - 6.96E+07 - - - -0.9964 - 1.675 0.571 - 211.7 1 2 0 -0.0016 12 0 0 0 1.19E+08 2.59E+09 - - - 4.6151 1 221125_WJC_METTL3_EV_vs_WT_F02.23442.23442.3 1.57E-05 Dec-44 R.LFPPQWIC[160.03]C[160.03]DIR[166.11].Y sp|Q86U44|MTA70_HUMAN 1 1613.7722 0.05 22149 23442 3 1613.77064 538.9313 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 5.82 3816.3 - 1.65E+07 - - - -0.9729 - 2.244 0.591 - 186.7 1 2 0 -0.0016 12 0 0 0 5.64E+06 1.25E+08 - - - 7.369 1 221125_WJC_METTL3_EV_vs_WT_F02.23444.23444.3 3.47E-11 20/72 R.AIAELGIYPAVDPLDSTSR[166.11].L "sp|P06576|ATPB_HUMAN,tr|H0YH81|H0YH81_HUMAN" 2 1997.0345 1.82 22151 23444 3 1997.033711 666.6854 "ATP synthase subunit beta, mitochondrial OS=Homo sapiens OX=9606 GN=ATP5F1B PE=1 SV=3" 4.03 3816.4 - 7.24E+06 - - - -0.3911 - 3.483 0.596 - 470.4 1 2 0 -0.0008 19 0 0 0 9.80E+07 5.38E+07 - - - 8.2504 1 221125_WJC_METTL3_EV_vs_WT_F02.23445.23445.2 3.36E-06 28-Dec R.GFGFVTFADPASVDK.V "sp|Q96DH6|MSI2H_HUMAN,tr|B4DHE8|B4DHE8_HUMAN,tr|A0A6Q8PF05|A0A6Q8PF05_HUMAN,tr|J3QKT5|J3QKT5_HUMAN,tr|A0A6Q8PFU8|A0A6Q8PFU8_HUMAN,tr|J3KTC1|J3KTC1_HUMAN,tr|A0A6Q8PHT3|A0A6Q8PHT3_HUMAN" 7 1556.7511 1.76 22152 23445 2 1556.752672 779.3828 RNA-binding protein Musashi homolog 2 OS=Homo sapiens OX=9606 GN=MSI2 PE=1 SV=1 4.21 3816.5 - 2.43E+06 - - - 1.0034 - 2.812 0.606 - 404.9 1 2 0 0.0016 15 0 0 0 4.08E+08 2.32E+08 - - - 6.0583 1 221125_WJC_METTL3_EV_vs_WT_F02.23446.23446.3 5.77E-06 16/64 K.WFGSDVLQQPLPSMPAK.V "sp|Q9NRA8|4ET_HUMAN,tr|B1AKL4|B1AKL4_HUMAN" 2 1899.9553 0.69 22153 23446 3 1899.953486 634.3257 Eukaryotic translation initiation factor 4E transporter OS=Homo sapiens OX=9606 GN=EIF4ENIF1 PE=1 SV=2 5.84 3816.6 - 2.28E+06 - - - -0.9574 - 2.519 0.543 - 311.6 1 2 0 -0.0018 17 0 0 0 2.27E+07 3.31E+07 - - - 6.9274 0.9996 221125_WJC_METTL3_EV_vs_WT_F02.23447.23447.2 2.51E-11 16/32 K.WFGSDVLQQPLPSMPAK[136.11].V "sp|Q9NRA8|4ET_HUMAN,tr|B1AKL4|B1AKL4_HUMAN" 2 1907.9695 1.21 22154 23447 2 1907.965241 954.992 Eukaryotic translation initiation factor 4E transporter OS=Homo sapiens OX=9606 GN=EIF4ENIF1 PE=1 SV=2 5.84 3816.7 - 1.82E+06 - - - -2.2348 - 3.256 0.355 - 570.7 1 2 0 -0.0043 17 0 0 0 2.33E+07 1.93E+07 - - - 4.564 1 221125_WJC_METTL3_EV_vs_WT_F02.23448.23448.3 2.39E-10 32/124 R.FGGFGGPGGVGGLGGPGGFGPGGYPGGIHEVS.V sp|P35908|K22E_HUMAN 1 2757.2936 - 22155 23448 3 2757.280879 920.1051 "Keratin, type II cytoskeletal 2 epidermal OS=Homo sapiens OX=9606 GN=KRT2 PE=1 SV=2" 5.24 3816.8 - 1.47E+06 - - - -4.6002 - 4.375 0.609 - 467.1 1 1 0 -0.0127 32 0 0 0 - - - - - 8.7218 0.9993 221125_WJC_METTL3_EV_vs_WT_F02.23449.23449.2 9.20E-05 14/28 R.AAQAPSSFQLLYDLK.L "sp|P11586|C1TC_HUMAN,tr|F5H2F4|F5H2F4_HUMAN,tr|V9GZ78|V9GZ78_HUMAN,tr|V9GYY3|V9GYY3_HUMAN,tr|A0A494C1T2|A0A494C1T2_HUMAN" 5 1650.8617 0.85 22156 23449 2 1650.856021 826.4381 "C-1-tetrahydrofolate synthase, cytoplasmic OS=Homo sapiens OX=9606 GN=MTHFD1 PE=1 SV=4" 5.88 3817 - 1.08E+06 - - - -3.454 - 2.6 0.497 - 462.2 1 2 0 -0.0057 15 0 0 0 4.79E+07 5.62E+07 - - - 5.0592 0.9998 221125_WJC_METTL3_EV_vs_WT_F02.23450.23450.3 6.61E-06 15/52 R.WSPIASTLPELVQR.L "sp|Q13561|DCTN2_HUMAN,tr|H0YI98|H0YI98_HUMAN,tr|A8K8J9|A8K8J9_HUMAN,tr|A0A7I2V4H4|A0A7I2V4H4_HUMAN,tr|A0A7I2V4Y9|A0A7I2V4Y9_HUMAN" 5 1595.8671 3.57 22157 23450 3 1595.870209 532.963 Dynactin subunit 2 OS=Homo sapiens OX=9606 GN=DCTN2 PE=1 SV=4 6 3817.1 - 768695 - - - 1.9218 - 2.607 0.374 - 291.9 1 2 0 0.0031 14 0 0 0 8.30E+06 2.33E+06 - - - 5.2553 0.9999 221125_WJC_METTL3_EV_vs_WT_F02.23451.23451.2 2.07E-08 13/30 R.LFVGNLPTDITEEDFK[136.11].R "sp|Q8WXF1|PSPC1_HUMAN,tr|X6RDA4|X6RDA4_HUMAN" 2 1844.9287 0.69 22158 23451 2 1844.930471 923.4716 Paraspeckle component 1 OS=Homo sapiens OX=9606 GN=PSPC1 PE=1 SV=1 3.92 3817.2 - 762750 - - - 0.935 - 2.593 0.573 - 376 1 2 0 0.0017 16 0 0 0 3.11E+06 4.53E+06 - - - 5.6152 0.9997 221125_WJC_METTL3_EV_vs_WT_F02.23454.23454.2 1.12E-09 14/22 K.NFFYIISPGVTK.V sp|Q10472|GALT1_HUMAN 1 1384.7391 2.25 22161 23454 2 1384.741913 693.3768 Polypeptide N-acetylgalactosaminyltransferase 1 OS=Homo sapiens OX=9606 GN=GALNT1 PE=1 SV=1 8.59 3817.6 - 673386 - - - 2.0401 - 2.367 0.513 - 720.5 1 2 0 0.0028 12 0 0 0 6.47E+06 2.87E+06 - - - 5.0962 1 221125_WJC_METTL3_EV_vs_WT_F02.23463.23463.2 2.15E-09 17/28 K.VSQEILELLNTTTAK[136.11].E "sp|Q86U44|MTA70_HUMAN,tr|H0YFV6|H0YFV6_HUMAN" 2 1666.9233 0.001 22168 23463 2 1666.92117 834.4689 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 4.53 3818.6 - 1.63E+07 - - - -1.258 - 3.45 0.568 - 1199.7 1 2 0 -0.0021 15 0 0 0 0.00E+00 1.41E+08 - - - 6.2802 1 221125_WJC_METTL3_EV_vs_WT_F02.23464.23464.2 9.19E-13 15/28 R.GFGFVTFADPASVDK[136.11].V "sp|Q96DH6|MSI2H_HUMAN,tr|B4DHE8|B4DHE8_HUMAN,tr|A0A6Q8PF05|A0A6Q8PF05_HUMAN,tr|J3QKT5|J3QKT5_HUMAN,tr|A0A6Q8PFU8|A0A6Q8PFU8_HUMAN,tr|J3KTC1|J3KTC1_HUMAN,tr|A0A6Q8PHT3|A0A6Q8PHT3_HUMAN" 7 1564.7653 1.76 22169 23464 2 1564.767181 783.3899 RNA-binding protein Musashi homolog 2 OS=Homo sapiens OX=9606 GN=MSI2 PE=1 SV=1 4.21 3818.7 - 4.73E+06 - - - 1.1957 - 2.894 0.694 - 702.7 1 2 0 0.0019 15 0 0 0 4.08E+08 2.32E+08 - - - 6.7788 0.9999 221125_WJC_METTL3_EV_vs_WT_F02.23465.23465.2 2.34E-05 13/24 K.AAILPTSIFLTNK.K "sp|O14744|ANM5_HUMAN,tr|H0YJX6|H0YJX6_HUMAN" 2 1387.8075 2.85 22170 23465 2 1387.808307 694.911 Protein arginine N-methyltransferase 5 OS=Homo sapiens OX=9606 GN=PRMT5 PE=1 SV=4 8.8 3818.7 - 4.10E+06 - - - 0.5801 - 2.416 0.535 - 478.2 1 2 0 0.0008 13 0 0 0 8.66E+07 3.04E+07 - - - 5.2562 1 221125_WJC_METTL3_EV_vs_WT_F02.23466.23466.3 5.12E-10 19/100 R.NVLLDPQLVPGGGASEMAVAHALTEK[136.11].S "sp|P49368|TCPG_HUMAN,tr|B4DUR8|B4DUR8_HUMAN" 2 2624.3723 0.21 22171 23466 3 2624.372063 875.7981 T-complex protein 1 subunit gamma OS=Homo sapiens OX=9606 GN=CCT3 PE=1 SV=4 4.65 3818.8 - 2.91E+06 - - - -0.1048 - 3.854 0.643 - 251.1 1 2 0 -0.0003 26 0 0 0 2.24E+07 1.06E+08 - - - 8.8126 1 221125_WJC_METTL3_EV_vs_WT_F02.23467.23467.2 4.15E-08 13/26 R.WSPIASTLPELVQR.L "sp|Q13561|DCTN2_HUMAN,tr|H0YI98|H0YI98_HUMAN,tr|A8K8J9|A8K8J9_HUMAN,tr|A0A7I2V4H4|A0A7I2V4H4_HUMAN,tr|A0A7I2V4Y9|A0A7I2V4Y9_HUMAN" 5 1595.8671 23.5 22172 23467 2 1595.868545 798.9408 Dynactin subunit 2 OS=Homo sapiens OX=9606 GN=DCTN2 PE=1 SV=4 6 3818.9 - 2.23E+06 - - - 0.8791 - 2.644 0.584 - 573.9 1 2 0 0.0014 14 0 0 0 4.49E+07 1.91E+06 - - - 5.7939 1 221125_WJC_METTL3_EV_vs_WT_F02.23468.23468.2 8.83E-12 22/34 K.GPTEQLVSPEPEVYEILR.A "sp|O75688|PPM1B_HUMAN,tr|A0A3B3IS24|A0A3B3IS24_HUMAN,tr|C9JIR6|C9JIR6_HUMAN" 3 2055.0524 3.87 22173 23468 2 2055.053995 1028.5335 Protein phosphatase 1B OS=Homo sapiens OX=9606 GN=PPM1B PE=1 SV=1 4.09 3819 - 1.91E+06 - - - 0.7581 - 4.391 0.641 - 1182.6 1 2 0 0.0016 18 0 0 0 2.33E+08 6.01E+07 - - - 7.4125 1 221125_WJC_METTL3_EV_vs_WT_F02.23469.23469.3 3.59E-09 20/60 -.MR[166.11]DPVSSQYSSFLFWR[166.11].M sp|Q13015|AF1Q_HUMAN 1 2024.9682 1.43 22174 23469 3 2024.968726 675.9967 Protein AF1q OS=Homo sapiens OX=9606 GN=MLLT11 PE=1 SV=1 8.5 3819 - 1.51E+06 - - - 0.281 - 3.803 0.563 - 792.6 1 2 1 0.0006 16 0 0 0 1.18E+07 8.27E+06 - - - 8.2442 1 221125_WJC_METTL3_EV_vs_WT_F02.23470.23470.2 3.35E-10 15/26 K.VVSSVLQFGNISFK.K sp|P35580|MYH10_HUMAN 1 1523.8348 0.91 22175 23470 2 1523.834608 762.9247 Myosin-10 OS=Homo sapiens OX=9606 GN=MYH10 PE=1 SV=3 8.72 3819.2 - 1.43E+06 - - - -0.1129 - 3 0.628 - 697.5 1 2 0 -0.0002 14 0 0 0 1.52E+07 1.66E+07 - - - 6.4363 1 221125_WJC_METTL3_EV_vs_WT_F02.23473.23473.3 3.44E-06 17/56 R.AAQAPSSFQLLYDLK.L "sp|P11586|C1TC_HUMAN,tr|F5H2F4|F5H2F4_HUMAN,tr|V9GZ78|V9GZ78_HUMAN,tr|V9GYY3|V9GYY3_HUMAN,tr|A0A494C1T2|A0A494C1T2_HUMAN" 5 1650.8617 0.47 22178 23473 3 1650.863948 551.2945 "C-1-tetrahydrofolate synthase, cytoplasmic OS=Homo sapiens OX=9606 GN=MTHFD1 PE=1 SV=4" 5.88 3819.5 - 1.17E+06 - - - 1.3478 - 3.014 0.474 - 255.4 1 2 0 0.0022 15 0 0 0 1.42E+07 2.98E+07 - - - 6.7028 1 221125_WJC_METTL3_EV_vs_WT_F02.23474.23474.2 1.59E-07 14/24 T.FIGNSTAIQELFK.R "sp|P04350|TBB4A_HUMAN,sp|Q9BVA1|TBB2B_HUMAN,sp|P07437|TBB5_HUMAN,sp|Q13509|TBB3_HUMAN,sp|Q13885|TBB2A_HUMAN,sp|P68371|TBB4B_HUMAN,sp|Q9BUF5|TBB6_HUMAN,tr|A0A0B4J269|A0A0B4J269_HUMAN,tr|Q5ST81|Q5ST81_HUMAN,tr|Q5JP53|Q5JP53_HUMAN" 10 1466.7769 1.9 22179 23474 2 1466.77795 734.3957 Tubulin beta-4A chain OS=Homo sapiens OX=9606 GN=TUBB4A PE=1 SV=2 6 3819.6 - 1.09E+06 - - - 0.6954 - 2.799 0.559 - 423.9 1 1 0 0.001 13 0 0 0 1.25E+07 6.59E+06 - - - 5.8111 0.9617 221125_WJC_METTL3_EV_vs_WT_F02.23475.23475.3 0.000296 13/56 R.ALTVPELTQQVFDAK.N "sp|P07437|TBB5_HUMAN,tr|Q5ST81|Q5ST81_HUMAN,tr|Q5JP53|Q5JP53_HUMAN" 3 1658.8879 0.33 22180 23475 3 1658.885041 553.9699 Tubulin beta chain OS=Homo sapiens OX=9606 GN=TUBB PE=1 SV=2 4.37 3819.7 - 1.05E+06 - - - -1.7457 - 2.242 0.054 - 143 1 2 0 -0.0029 15 0 0 0 1.46E+07 4.39E+07 - - - 1.248 1 221125_WJC_METTL3_EV_vs_WT_F02.23476.23476.3 2.78E-06 19/52 K.LVINGNPITIFQER[166.11].D sp|P04406|G3P_HUMAN 1 1622.902 1.1 22181 23476 3 1622.901762 541.9746 Glyceraldehyde-3-phosphate dehydrogenase OS=Homo sapiens OX=9606 GN=GAPDH PE=1 SV=3 6 3819.9 - 953368 - - - -0.1226 - 3.116 0.478 - 399.5 1 2 0 -0.0002 14 0 0 0 3.96E+08 3.61E+08 - - - 6.8896 0.9999 221125_WJC_METTL3_EV_vs_WT_F02.23478.23478.2 4.83E-05 16/30 K.NSPDLGPIGGPPNGML.- "sp|Q8TB72|PUM2_HUMAN,tr|A0A0C4DG68|A0A0C4DG68_HUMAN" 2 1534.745 - 22183 23478 2 1534.745456 768.3798 Pumilio homolog 2 OS=Homo sapiens OX=9606 GN=PUM2 PE=1 SV=2 3.8 3820.1 - 778412 - - - 0.3115 - 2.464 0.488 - 571.5 1 2 0 0.0005 16 0 0 0 - - - - - 4.8623 1 221125_WJC_METTL3_EV_vs_WT_F02.23479.23479.3 3.60E-10 16/72 K.VNFPENGFLSPDK[136.11]LSLLEK[136.11].L sp|P31689|DNJA1_HUMAN 1 2162.1594 0.97 22184 23479 3 2162.161117 721.7271 DnaJ homolog subfamily A member 1 OS=Homo sapiens OX=9606 GN=DNAJA1 PE=1 SV=2 4.68 3820.3 - 659125 - - - 0.7844 - 3.443 0.623 - 218.5 1 2 1 0.0017 19 0 0 0 7.71E+06 7.94E+06 - - - 8.5228 1 221125_WJC_METTL3_EV_vs_WT_F02.23480.23480.3 5.10E-06 16/60 R.EAEAAIYHLQLFEELR.R "sp|P14618|KPYM_HUMAN,tr|B4DNK4|B4DNK4_HUMAN" 2 1930.9789 -1 22185 23480 3 1930.980108 644.6669 Pyruvate kinase PKM OS=Homo sapiens OX=9606 GN=PKM PE=1 SV=4 4.48 3820.4 - 642781 - - - 0.637 - 2.959 0.453 - 158.1 1 2 0 0.0012 16 0 0 0 0.00E+00 0.00E+00 - - - 6.3737 0.9999 221125_WJC_METTL3_EV_vs_WT_F02.23482.23482.3 1.20E-05 13/52 K.VVSSVLQFGNISFK[136.11].K sp|P35580|MYH10_HUMAN 1 1531.849 0.7 22186 23482 3 1531.851492 511.6236 Myosin-10 OS=Homo sapiens OX=9606 GN=MYH10 PE=1 SV=3 8.72 3820.7 - 731092 - - - 1.6398 - 2.351 0.425 - 207.6 1 2 0 0.0025 14 0 0 0 2.55E+06 3.64E+06 - - - 5.5494 0.9998 221125_WJC_METTL3_EV_vs_WT_F02.23483.23483.3 0.013 Nov-44 R.EQLMFPFHFVDR.L sp|P82933|RT09_HUMAN 1 1564.7497 0.91 22187 23483 3 1564.751899 522.5905 "28S ribosomal protein S9, mitochondrial OS=Homo sapiens OX=9606 GN=MRPS9 PE=1 SV=2" 5.32 3820.9 - 509878 - - - 1.4245 - 2.164 0.393 - 165.7 1 2 0 0.0022 12 0 0 0 4.05E+06 4.45E+06 - - - 5.0607 0.9997 221125_WJC_METTL3_EV_vs_WT_F02.23485.23485.2 1.07E-06 13/28 R.AAQAPSSFQLLYDLK[136.11].L "sp|P11586|C1TC_HUMAN,tr|F5H2F4|F5H2F4_HUMAN,tr|V9GZ78|V9GZ78_HUMAN,tr|V9GYY3|V9GYY3_HUMAN,tr|A0A494C1T2|A0A494C1T2_HUMAN" 5 1658.8759 1.12 22189 23485 2 1658.878912 830.4452 "C-1-tetrahydrofolate synthase, cytoplasmic OS=Homo sapiens OX=9606 GN=MTHFD1 PE=1 SV=4" 5.88 3820.9 - 5.80E+06 - - - 1.8018 - 2.538 0.416 - 350.8 1 2 0 0.003 15 0 0 0 4.70E+07 4.22E+07 - - - 4.4025 0.9999 221125_WJC_METTL3_EV_vs_WT_F02.23486.23486.2 1.15E-05 13/24 K.AAILPTSIFLTNK[136.11].K "sp|O14744|ANM5_HUMAN,tr|H0YJX6|H0YJX6_HUMAN" 2 1395.8217 2.85 22190 23486 2 1395.821504 698.9181 Protein arginine N-methyltransferase 5 OS=Homo sapiens OX=9606 GN=PRMT5 PE=1 SV=4 8.8 3821 - 4.46E+06 - - - -0.1419 - 2.37 0.521 - 454.6 1 2 0 -0.0002 13 0 0 0 8.66E+07 3.04E+07 - - - 5.1037 1 221125_WJC_METTL3_EV_vs_WT_F02.23489.23489.3 1.76E-08 22/100 R.NVLLDPQLVPGGGASEMAVAHALTEK.S "sp|P49368|TCPG_HUMAN,tr|B4DUR8|B4DUR8_HUMAN" 2 2616.3581 0.21 22193 23489 3 2616.357489 873.1267 T-complex protein 1 subunit gamma OS=Homo sapiens OX=9606 GN=CCT3 PE=1 SV=4 4.65 3821.2 - 2.61E+06 - - - -0.2481 - 3.291 0.601 - 323.7 1 2 0 -0.0006 26 0 0 0 2.24E+07 1.06E+08 - - - 7.9809 0.7833 221125_WJC_METTL3_EV_vs_WT_F02.23494.23494.2 0.246 26-Aug Q.ENGNASVISQQIIR[166.11].S "sp|Q86WP2|GPBP1_HUMAN,tr|D4PHA4|D4PHA4_HUMAN" 2 1537.8088 4.27 22198 23494 2 1537.810308 769.9117 Vasculin OS=Homo sapiens OX=9606 GN=GPBP1 PE=1 SV=1 6.1 3821.8 - 992663 - - - 0.9878 - 1.513 0.174 - 136 1 1 0 0.0015 14 0 0 0 2.20E+07 5.15E+06 - - - 1.3648 1 221125_WJC_METTL3_EV_vs_WT_F02.23495.23495.2 2.50E-10 16/24 K.AQNIMESFENPFR.M sp|Q01780|EXOSX_HUMAN 1 1581.7246 0.58 22199 23495 2 1581.724424 791.8696 Exosome component 10 OS=Homo sapiens OX=9606 GN=EXOSC10 PE=1 SV=2 4.53 3821.9 - 883220 - - - -0.0967 - 3.189 0.639 - 643 1 2 0 -0.0002 13 0 0 0 5.00E+06 8.56E+06 - - - 6.737 0.9997 221125_WJC_METTL3_EV_vs_WT_F02.23496.23496.2 0.000142 24-Oct K.AALLNFDEFAVSK.D "sp|Q9Y613|FHOD1_HUMAN,tr|J3KTH7|J3KTH7_HUMAN" 2 1423.7347 1.42 22200 23496 2 1423.73629 712.8746 FH1\FH2 domain-containing protein 1 OS=Homo sapiens OX=9606 GN=FHOD1 PE=1 SV=3 4.37 3822 - 781037 - - - 1.095 - 2.157 0.424 - 318.5 1 2 0 0.0016 13 0 0 0 4.40E+06 3.10E+06 - - - 4.1451 0.9998 221125_WJC_METTL3_EV_vs_WT_F02.23497.23497.2 1.85E-05 24-Nov K.AALLNFDEFAVSK[136.11].D "sp|Q9Y613|FHOD1_HUMAN,tr|J3KTH7|J3KTH7_HUMAN" 2 1431.7489 1.51 22201 23497 2 1431.749301 716.8817 FH1\FH2 domain-containing protein 1 OS=Homo sapiens OX=9606 GN=FHOD1 PE=1 SV=3 4.37 3822.1 - 729941 - - - 0.2584 - 2.288 0.451 - 433.9 1 2 0 0.0004 13 0 0 0 4.69E+06 3.10E+06 - - - 4.4962 0.9996 221125_WJC_METTL3_EV_vs_WT_F02.23498.23498.3 3.50E-05 Sep-56 K.YTYMEEMLGNVAGAR.Q "sp|Q9BZJ0|CRNL1_HUMAN,tr|Q5JY65|Q5JY65_HUMAN" 2 1703.7647 1.66 22202 23498 3 1703.768014 568.9289 Crooked neck-like protein 1 OS=Homo sapiens OX=9606 GN=CRNKL1 PE=1 SV=4 4.53 3822.3 - 517783 - - - 1.9293 - 1.716 0.415 - 70.1 1 2 0 0.0033 15 0 0 0 2.64E+06 1.59E+06 - - - 4.575 1 221125_WJC_METTL3_EV_vs_WT_F02.23499.23499.3 1.87E-06 15/64 K.AC[160.03]ANPAAGSVILLENLR[166.11].F sp|P00558|PGK1_HUMAN 1 1777.9384 2.1 22203 23499 3 1777.939557 593.6534 Phosphoglycerate kinase 1 OS=Homo sapiens OX=9606 GN=PGK1 PE=1 SV=3 6.04 3822.4 - 490084 - - - 0.6373 - 2.646 0.46 - 295.2 1 2 0 0.0011 17 0 0 0 7.31E+06 3.48E+06 - - - 6.1264 0.9999 221125_WJC_METTL3_EV_vs_WT_F02.23504.23504.2 0.000161 26-Oct K.LVINGNPITIFQER.D sp|P04406|G3P_HUMAN 1 1612.8937 1.09 22206 23504 2 1612.894113 807.4541 Glyceraldehyde-3-phosphate dehydrogenase OS=Homo sapiens OX=9606 GN=GAPDH PE=1 SV=3 6 3823.1 - 1.07E+08 - - - 0.2616 - 1.905 0.556 - 215.5 1 2 0 0.0004 14 0 0 0 1.71E+09 1.57E+09 - - - 4.7648 1 221125_WJC_METTL3_EV_vs_WT_F02.23505.23505.3 7.39E-09 17/68 K.GPTEQLVSPEPEVYEILR[166.11].A "sp|O75688|PPM1B_HUMAN,tr|A0A3B3IS24|A0A3B3IS24_HUMAN,tr|C9JIR6|C9JIR6_HUMAN" 3 2065.0607 3.65 22207 23505 3 2065.060915 689.3608 Protein phosphatase 1B OS=Homo sapiens OX=9606 GN=PPM1B PE=1 SV=1 4.09 3823.1 - 3.07E+07 - - - 0.1007 - 3.064 0.566 - 344.8 1 2 0 0.0002 18 0 0 0 4.08E+08 1.12E+08 - - - 7.6385 0.9999 221125_WJC_METTL3_EV_vs_WT_F02.23506.23506.3 0.000268 Jul-52 K.LVINGNPITIFQER.D sp|P04406|G3P_HUMAN 1 1612.8937 1.1 22208 23506 3 1612.892094 538.6385 Glyceraldehyde-3-phosphate dehydrogenase OS=Homo sapiens OX=9606 GN=GAPDH PE=1 SV=3 6 3823.1 - 2.94E+07 - - - -0.9901 - 1.761 0.448 - 45.5 1 2 0 -0.0016 14 0 0 0 3.96E+08 3.61E+08 - - - 5.0382 1 221125_WJC_METTL3_EV_vs_WT_F02.23507.23507.2 1.83E-11 16/34 K.GPTEQLVSPEPEVYEILR[166.11].A "sp|O75688|PPM1B_HUMAN,tr|A0A3B3IS24|A0A3B3IS24_HUMAN,tr|C9JIR6|C9JIR6_HUMAN" 3 2065.0607 3.87 22209 23507 2 2065.057136 1033.5376 Protein phosphatase 1B OS=Homo sapiens OX=9606 GN=PPM1B PE=1 SV=1 4.09 3823.2 - 1.82E+07 - - - -1.7292 - 3.47 0.675 - 477 1 2 0 -0.0036 18 0 0 0 2.33E+08 6.01E+07 - - - 7.0842 0.9998 221125_WJC_METTL3_EV_vs_WT_F02.23514.23514.2 4.62E-07 26-Nov R.ALESSLWELQALQR.H sp|Q9BVI4|NOC4L_HUMAN 1 1642.8679 0.63 22216 23514 2 1642.864346 822.4412 Nucleolar complex protein 4 homolog OS=Homo sapiens OX=9606 GN=NOC4L PE=1 SV=1 4.53 3823.6 - 3.65E+06 - - - -2.1456 - 2.506 0.574 - 356.5 1 2 0 -0.0035 14 0 0 0 1.19E+07 1.88E+07 - - - 5.5849 0.9998 221125_WJC_METTL3_EV_vs_WT_F02.23517.23517.2 7.54E-07 13/26 K.VAC[160.03]ITEQVLTLVNK.R "sp|P04843|RPN1_HUMAN,tr|B7Z4L4|B7Z4L4_HUMAN" 2 1586.8702 -1 22219 23517 2 1586.872949 794.4424 Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit 1 OS=Homo sapiens OX=9606 GN=RPN1 PE=1 SV=1 5.97 3824 - 2.98E+06 - - - 1.7456 - 2.646 0.531 - 272.6 1 2 0 0.0028 14 0 0 0 0.00E+00 0.00E+00 - - - 5.4039 1 221125_WJC_METTL3_EV_vs_WT_F02.23518.23518.2 3.85E-08 14/26 R.EWYPSLATMQESLR.V sp|Q8TAE8|G45IP_HUMAN 1 1709.8083 10.97 22220 23518 2 1709.805545 855.9114 Growth arrest and DNA damage-inducible proteins-interacting protein 1 OS=Homo sapiens OX=9606 GN=GADD45GIP1 PE=1 SV=1 4.53 3824.1 - 2.89E+06 - - - -1.6154 - 2.831 0.615 - 578.1 1 2 0 -0.0028 14 0 0 0 8.11E+07 7.39E+06 - - - 6.1939 0.9998 221125_WJC_METTL3_EV_vs_WT_F02.23521.23521.2 0.000268 28-Oct R.DYLHLPPEIVPATLR.R "sp|P46783|RS10_HUMAN,tr|A0A2R8Y6L3|A0A2R8Y6L3_HUMAN,tr|F6U211|F6U211_HUMAN,tr|A0A1W2PQS6|A0A1W2PQS6_HUMAN,tr|A0A2R8YFH6|A0A2R8YFH6_HUMAN,tr|A0A2R8Y7H1|A0A2R8Y7H1_HUMAN,tr|S4R435|S4R435_HUMAN" 7 1732.9512 1.99 22223 23521 2 1732.950752 867.4829 40S ribosomal protein S10 OS=Homo sapiens OX=9606 GN=RPS10 PE=1 SV=1 5.32 3824.4 - 2.45E+06 - - - -0.262 - 2.046 0.413 - 155.4 1 2 0 -0.0005 15 0 0 0 6.80E+06 3.41E+06 - - - 3.8513 0.9973 221125_WJC_METTL3_EV_vs_WT_F02.23523.23523.2 0.11 Sep-32 K.AVIVIQDIFGWQLPNTR[166.11].Y sp|Q96DG6|CMBL_HUMAN 1 1979.0868 0.01 22225 23523 2 1979.084395 990.5507 Carboxymethylenebutenolidase homolog OS=Homo sapiens OX=9606 GN=CMBL PE=1 SV=1 5.88 3824.6 - 1.57E+06 - - - -1.2162 - 1.729 0.19 - 97.2 1 2 0 -0.0024 17 0 0 0 2.76E+05 4.36E+07 - - - 1.7897 0.9993 221125_WJC_METTL3_EV_vs_WT_F02.23526.23526.3 0.00984 Oct-48 K.AAILPTSIFLTNK.K "sp|O14744|ANM5_HUMAN,tr|H0YJX6|H0YJX6_HUMAN" 2 1387.8075 6.5 22227 23526 3 1387.805186 463.6098 Protein arginine N-methyltransferase 5 OS=Homo sapiens OX=9606 GN=PRMT5 PE=1 SV=4 8.8 3824.9 - 400736 - - - -1.6688 - 1.818 0.33 - 130.7 1 2 0 -0.0023 13 0 0 0 3.85E+06 5.93E+05 - - - 3.8392 0.955 221125_WJC_METTL3_EV_vs_WT_F02.23527.23527.2 0.00529 Aug-32 K.VGGTNLGAPGAFGQSPF.S sp|Q96I24|FUBP3_HUMAN 1 1575.7682 - 22228 23527 2 1575.769067 788.8914 Far upstream element-binding protein 3 OS=Homo sapiens OX=9606 GN=FUBP3 PE=1 SV=2 5.49 3824.9 - 1.29E+07 - - - 0.5775 - 1.445 0.372 - 77.4 1 1 0 0.0009 17 0 0 0 - - - - - 2.6933 1 221125_WJC_METTL3_EV_vs_WT_F02.23528.23528.2 1.62E-11 17/30 K.MFIGGLSWQTSPDSLR.D "sp|Q96DH6|MSI2H_HUMAN,tr|B4DHE8|B4DHE8_HUMAN,tr|A0A6Q8PF05|A0A6Q8PF05_HUMAN,tr|J3QKT5|J3QKT5_HUMAN,tr|A0A6Q8PFU8|A0A6Q8PFU8_HUMAN,tr|J3KTC1|J3KTC1_HUMAN,tr|A0A6Q8PHT3|A0A6Q8PHT3_HUMAN" 7 1793.8771 1.83 22229 23528 2 1793.875816 897.9458 RNA-binding protein Musashi homolog 2 OS=Homo sapiens OX=9606 GN=MSI2 PE=1 SV=1 5.59 3825 - 2.58E+06 - - - -0.6907 - 3.242 0.678 - 957.8 1 2 0 -0.0012 16 0 0 0 5.94E+07 3.24E+07 - - - 6.94 1 221125_WJC_METTL3_EV_vs_WT_F02.23532.23532.3 5.47E-08 13/80 R.TFFPEYTHQLFGDDETAFGYK.G sp|O14929|HAT1_HUMAN 1 2512.1223 0.63 22233 23532 3 2512.120535 838.3814 Histone acetyltransferase type B catalytic subunit OS=Homo sapiens OX=9606 GN=HAT1 PE=1 SV=1 4.31 3825.5 - 866930 - - - -0.7054 - 2.589 0.578 - 107.1 1 2 0 -0.0018 21 0 0 0 2.83E+06 4.49E+06 - - - 7.2643 0.9715 221125_WJC_METTL3_EV_vs_WT_F02.23533.23533.2 7.07E-05 20-Nov V.SPEPEVYEILR.A "sp|O75688|PPM1B_HUMAN,tr|A0A3B3IS24|A0A3B3IS24_HUMAN,tr|C9JIR6|C9JIR6_HUMAN" 3 1330.6769 12.53 22234 23533 2 1330.673314 666.3457 Protein phosphatase 1B OS=Homo sapiens OX=9606 GN=PPM1B PE=1 SV=1 4.25 3825.7 - 770198 - - - -2.6813 - 2.253 0.459 - 416.2 1 1 0 -0.0036 11 0 0 0 4.38E+07 3.50E+06 - - - 4.6274 1 221125_WJC_METTL3_EV_vs_WT_F02.23536.23536.3 2.16E-13 25/96 R.YMEEMADTADAIEMATLDKEMAEER.A "sp|Q14203|DCTN1_HUMAN,tr|A0A804CDA6|A0A804CDA6_HUMAN,tr|E7EX90|E7EX90_HUMAN,tr|A0A7P0Z4C3|A0A7P0Z4C3_HUMAN,tr|Q6AWB1|Q6AWB1_HUMAN" 5 2892.2173 2.91 22237 23536 3 2892.214708 965.0797 Dynactin subunit 1 OS=Homo sapiens OX=9606 GN=DCTN1 PE=1 SV=3 3.84 3826.1 - 646754 - - - -0.9128 - 4.385 0.764 - 539.4 1 2 1 -0.0026 25 0 0 0 4.12E+06 1.41E+06 - - - 10.4579 1 221125_WJC_METTL3_EV_vs_WT_F02.23537.23537.3 1.21E-07 15/60 R.TPEQVAEEEYLLQELR[166.11].K "sp|Q9NPF5|DMAP1_HUMAN,tr|Q5TG39|Q5TG39_HUMAN,tr|Q5TG40|Q5TG40_HUMAN" 3 1955.9716 0.49 22238 23537 3 1955.968966 652.9978 DNA methyltransferase 1-associated protein 1 OS=Homo sapiens OX=9606 GN=DMAP1 PE=1 SV=1 3.98 3826.2 - 563622 - - - -1.3247 - 3.058 0.561 - 288.2 1 2 0 -0.0026 16 0 0 0 2.26E+06 4.57E+06 - - - 7.6619 0.9737 221125_WJC_METTL3_EV_vs_WT_F02.23539.23539.2 0.478 Apr-32 R.FEIGEGENLDLPYGLER[166.11].A sp|Q02790|FKBP4_HUMAN 1 1959.9453 -1 22240 23539 2 1959.944985 980.9799 Peptidyl-prolyl cis-trans isomerase FKBP4 OS=Homo sapiens OX=9606 GN=FKBP4 PE=1 SV=3 3.91 3826.5 - 0 - - - -0.1821 - 1.093 0.126 - 28.1 3 2 0 -0.0004 17 0 0 0 0.00E+00 0.00E+00 - - - -0.023 1 221125_WJC_METTL3_EV_vs_WT_F02.23541.23541.3 1.52E-10 18/68 K.GPTEQLVSPEPEVYEILR.A "sp|O75688|PPM1B_HUMAN,tr|A0A3B3IS24|A0A3B3IS24_HUMAN,tr|C9JIR6|C9JIR6_HUMAN" 3 2055.0524 3.65 22241 23541 3 2055.054047 686.0248 Protein phosphatase 1B OS=Homo sapiens OX=9606 GN=PPM1B PE=1 SV=1 4.09 3826.7 - 2.75E+07 - - - 0.7834 - 3.19 0.626 - 357.3 1 2 0 0.0016 18 0 0 0 4.08E+08 1.12E+08 - - - 8.4074 1 221125_WJC_METTL3_EV_vs_WT_F02.23543.23543.3 2.63E-07 14/56 R.DYLHLPPEIVPATLR.R "sp|P46783|RS10_HUMAN,tr|A0A2R8Y6L3|A0A2R8Y6L3_HUMAN,tr|F6U211|F6U211_HUMAN,tr|A0A1W2PQS6|A0A1W2PQS6_HUMAN,tr|A0A2R8YFH6|A0A2R8YFH6_HUMAN,tr|A0A2R8Y7H1|A0A2R8Y7H1_HUMAN,tr|S4R435|S4R435_HUMAN" 7 1732.9512 1.38 22242 23543 3 1732.950735 578.6577 40S ribosomal protein S10 OS=Homo sapiens OX=9606 GN=RPS10 PE=1 SV=1 5.32 3826.9 - 4.19E+06 - - - -0.2718 - 2.743 0.57 - 188.1 1 2 0 -0.0005 15 0 0 0 6.64E+07 4.82E+07 - - - 7.5278 1 221125_WJC_METTL3_EV_vs_WT_F02.23544.23544.2 2.05E-11 14/28 R.GFGFVTFESEDIVEK.V "sp|O43347|MSI1H_HUMAN,tr|H0YHB7|H0YHB7_HUMAN" 2 1702.809 1.35 22243 23544 2 1702.808591 852.4118 RNA-binding protein Musashi homolog 1 OS=Homo sapiens OX=9606 GN=MSI1 PE=1 SV=1 4 3827 - 2.40E+06 - - - -0.2508 - 2.984 0.654 - 677.9 1 2 0 -0.0004 15 0 0 0 1.83E+08 1.35E+08 - - - 6.5592 1 221125_WJC_METTL3_EV_vs_WT_F02.23546.23546.2 6.09E-10 19/30 K.LFVGGLDWSTTQETLR.S "sp|Q96EP5|DAZP1_HUMAN,tr|K7EK33|K7EK33_HUMAN,tr|K7EQ55|K7EQ55_HUMAN,tr|K7EQ02|K7EQ02_HUMAN" 4 1821.9261 1.34 22245 23546 2 1821.927881 911.9703 DAZ-associated protein 1 OS=Homo sapiens OX=9606 GN=DAZAP1 PE=1 SV=1 4.37 3827.2 - 1.80E+06 - - - 0.9699 - 3.577 0.664 - 1211.1 1 2 0 0.0018 16 0 0 0 2.45E+07 1.83E+07 - - - 7.0782 1 221125_WJC_METTL3_EV_vs_WT_F02.23547.23547.3 1.60E-07 15/60 K.MFIGGLSWQTSPDSLR.D "sp|Q96DH6|MSI2H_HUMAN,tr|B4DHE8|B4DHE8_HUMAN,tr|A0A6Q8PF05|A0A6Q8PF05_HUMAN,tr|J3QKT5|J3QKT5_HUMAN,tr|A0A6Q8PFU8|A0A6Q8PFU8_HUMAN,tr|J3KTC1|J3KTC1_HUMAN,tr|A0A6Q8PHT3|A0A6Q8PHT3_HUMAN" 7 1793.8771 1.52 22246 23547 3 1793.87717 598.9663 RNA-binding protein Musashi homolog 2 OS=Homo sapiens OX=9606 GN=MSI2 PE=1 SV=1 5.59 3827.3 - 1.67E+06 - - - 0.0641 - 2.575 0.548 - 282.1 1 2 0 0.0001 16 0 0 0 1.72E+07 1.14E+07 - - - 7.0765 1 221125_WJC_METTL3_EV_vs_WT_F02.23549.23549.3 0.000236 Dec-56 R.VFPLSC[160.03]AVQQYAWGK.M "sp|P34949|MPI_HUMAN,tr|H3BU66|H3BU66_HUMAN,tr|H3BQX0|H3BQX0_HUMAN,tr|H3BUZ9|H3BUZ9_HUMAN,tr|H3BPP3|H3BPP3_HUMAN,tr|H3BN01|H3BN01_HUMAN,tr|H3BMZ9|H3BMZ9_HUMAN,tr|H3BNY8|H3BNY8_HUMAN,tr|H3BUG1|H3BUG1_HUMAN" 9 1752.8658 1.45 22248 23549 3 1752.864449 585.2959 Mannose-6-phosphate isomerase OS=Homo sapiens OX=9606 GN=MPI PE=1 SV=2 8.17 3827.5 - 1.12E+06 - - - -0.7491 - 2.423 0.466 - 195.6 1 2 0 -0.0013 15 0 0 0 7.36E+06 5.08E+06 - - - 6.0444 0.9931 221125_WJC_METTL3_EV_vs_WT_F02.23550.23550.2 8.41E-08 22-Dec R.R[166.11]LNIPVLQDDGF.L sp|Q86U44|MTA70_HUMAN 1 1395.7386 0.18 22249 23550 2 1395.739254 698.8766 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 4.21 3827.7 - 995393 - - - 0.48 - 2.364 0.511 - 564.2 1 1 0 0.0007 12 0 0 0 7.00E+06 3.91E+07 - - - 5.0788 1 221125_WJC_METTL3_EV_vs_WT_F02.23551.23551.2 1.81E-08 15/26 K.GTDVNVFNTILTTR.S sp|P04083|ANXA1_HUMAN 1 1549.81 25.39 22250 23551 2 1549.813101 775.9123 Annexin A1 OS=Homo sapiens OX=9606 GN=ANXA1 PE=1 SV=2 5.84 3827.8 - 957672 - - - 1.9873 - 3.122 0.618 - 759.3 1 2 0 0.0031 14 0 0 0 9.60E+06 3.78E+05 - - - 6.4615 0.9999 221125_WJC_METTL3_EV_vs_WT_F02.23552.23552.2 1.11E-05 13/24 K.WNTDSVEEFLSEK[136.11].L "sp|O60613|SEP15_HUMAN,tr|A0A087X1G7|A0A087X1G7_HUMAN" 2 1590.7293 0.22 22251 23552 2 1590.729576 796.3719 Selenoprotein F OS=Homo sapiens OX=9606 GN=SELENOF PE=1 SV=4 4 3827.9 - 732629 - - - 0.1622 - 2.481 0.579 - 453.5 1 2 0 0.0003 13 0 0 0 1.74E+06 7.77E+06 - - - 5.6495 1 221125_WJC_METTL3_EV_vs_WT_F02.23560.23560.2 1.67E-07 14/22 K.ITAEEMYDIFGK[136.11].Y sp|Q9Y3B4|SF3B6_HUMAN 1 1423.6785 1.13 22257 23560 2 1423.676758 712.8465 Splicing factor 3B subunit 6 OS=Homo sapiens OX=9606 GN=SF3B6 PE=1 SV=1 4.14 3828.9 - 2.19E+06 - - - -1.2011 - 2.732 0.638 - 823.3 1 2 0 -0.0017 12 0 0 0 5.36E+07 4.73E+07 - - - 6.3971 1 221125_WJC_METTL3_EV_vs_WT_F02.23561.23561.2 1.18E-08 14/28 R.VFPLSC[160.03]AVQQYAWGK.M "sp|P34949|MPI_HUMAN,tr|H3BU66|H3BU66_HUMAN,tr|H3BQX0|H3BQX0_HUMAN,tr|H3BUZ9|H3BUZ9_HUMAN,tr|H3BPP3|H3BPP3_HUMAN,tr|H3BN01|H3BN01_HUMAN,tr|H3BMZ9|H3BMZ9_HUMAN,tr|H3BNY8|H3BNY8_HUMAN,tr|H3BUG1|H3BUG1_HUMAN" 9 1752.8658 0.53 22258 23561 2 1752.865431 877.4402 Mannose-6-phosphate isomerase OS=Homo sapiens OX=9606 GN=MPI PE=1 SV=2 8.17 3829 - 1.01E+06 - - - -0.1888 - 2.967 0.594 - 589.8 1 2 0 -0.0003 15 0 0 0 7.08E+06 1.32E+07 - - - 6.102 1 221125_WJC_METTL3_EV_vs_WT_F02.23562.23562.2 3.73E-07 22-Dec K.ITAEEMYDIFGK.Y sp|Q9Y3B4|SF3B6_HUMAN 1 1415.6643 1.13 22259 23562 2 1415.664589 708.8394 Splicing factor 3B subunit 6 OS=Homo sapiens OX=9606 GN=SF3B6 PE=1 SV=1 4.14 3829.1 - 2.75E+06 - - - 0.2267 - 2.454 0.65 - 565.1 1 2 0 0.0003 12 0 0 0 5.36E+07 4.73E+07 - - - 6.2039 0.9987 221125_WJC_METTL3_EV_vs_WT_F02.23564.23564.3 1.98E-09 19/64 K.VIHDNFGIVEGLMTTVH.A "sp|P04406|G3P_HUMAN,tr|E7EUT5|E7EUT5_HUMAN" 2 1880.9455 - 22261 23564 3 1880.947634 627.9891 Glyceraldehyde-3-phosphate dehydrogenase OS=Homo sapiens OX=9606 GN=GAPDH PE=1 SV=3 5.15 3829.3 - 1.82E+06 - - - 1.151 - 3.257 0.605 - 396.2 1 1 0 0.0022 17 0 0 0 - - - - - 8.2676 0.9998 221125_WJC_METTL3_EV_vs_WT_F02.23565.23565.2 0.00455 14/24 R.QVLALELPEALC[160.03]R.E sp|Q9HBH1|DEFM_HUMAN 1 1510.8177 0.52 22262 23565 2 1510.816548 756.4162 "Peptide deformylase, mitochondrial OS=Homo sapiens OX=9606 GN=PDF PE=1 SV=1" 4.53 3829.4 - 1.61E+06 - - - -0.7956 - 2.553 0.4 - 770.8 1 2 0 -0.0012 13 0 0 0 1.55E+07 2.96E+07 - - - 4.4006 1 221125_WJC_METTL3_EV_vs_WT_F02.23567.23567.3 7.13E-09 20/68 R.VPAGNWVLIEGVDQPIVK.T sp|Q15029|U5S1_HUMAN 1 1933.0673 2.41 22264 23567 3 1933.066488 645.363 116 kDa U5 small nuclear ribonucleoprotein component OS=Homo sapiens OX=9606 GN=EFTUD2 PE=1 SV=1 4.37 3829.6 - 1.43E+06 - - - -0.4195 - 3.535 0.578 - 636.5 1 2 0 -0.0008 18 0 0 0 2.51E+07 1.04E+07 - - - 8.1282 0.964 221125_WJC_METTL3_EV_vs_WT_F02.23569.23569.2 0.0089 20-Jul R.YC[160.03]MQLSQIQGL.L "sp|P08779|K1C16_HUMAN,tr|K7ENW6|K7ENW6_HUMAN" 2 1339.6264 - 22266 23569 2 1339.625595 670.8205 "Keratin, type I cytoskeletal 16 OS=Homo sapiens OX=9606 GN=KRT16 PE=1 SV=4" 5.52 3829.8 - 751150 - - - -0.633 - 1.496 0.37 - 134.8 1 1 0 -0.0008 11 0 0 0 - - - - - 2.8632 1 221125_WJC_METTL3_EV_vs_WT_F02.23574.23574.2 3.24E-08 17/30 K.LFIGGLPNYLNDDQVK[136.11].E "sp|P26368|U2AF2_HUMAN,tr|K7ENG2|K7ENG2_HUMAN" 2 1812.9501 0.24 22269 23574 2 1812.950281 907.4824 Splicing factor U2AF 65 kDa subunit OS=Homo sapiens OX=9606 GN=U2AF2 PE=1 SV=4 4.21 3830.5 - 2.37E+06 - - - 0.0723 - 2.95 0.616 - 726.3 1 2 0 0.0001 16 0 0 0 8.62E+06 3.56E+07 - - - 6.2504 1 221125_WJC_METTL3_EV_vs_WT_F02.23575.23575.2 1.86E-11 24/34 R.VPAGNWVLIEGVDQPIVK.T sp|Q15029|U5S1_HUMAN 1 1933.0673 2.34 22270 23575 2 1933.069451 967.5409 116 kDa U5 small nuclear ribonucleoprotein component OS=Homo sapiens OX=9606 GN=EFTUD2 PE=1 SV=1 4.37 3830.6 - 1.60E+06 - - - 1.1133 - 4.415 0.693 - 1838.4 1 2 0 0.0022 18 0 0 0 1.87E+07 7.98E+06 - - - 7.8098 1 221125_WJC_METTL3_EV_vs_WT_F02.23576.23576.2 6.27E-12 19/28 K.DC[160.03]EVVMMIGLPGAGK[136.11].T "sp|Q00839|HNRPU_HUMAN,tr|A0A1W2PQL0|A0A1W2PQL0_HUMAN,tr|A0A1W2PPL4|A0A1W2PPL4_HUMAN,tr|A0A1W2PQ74|A0A1W2PQ74_HUMAN,tr|Q5RI18|Q5RI18_HUMAN,tr|A0A1W2PP35|A0A1W2PP35_HUMAN,tr|A0A1W2PPS1|A0A1W2PPS1_HUMAN,tr|A0A1W2PRZ7|A0A1W2PRZ7_HUMAN,tr|A0A1W2PPH7|A0A1W2PPH7_HUMAN,tr|A0A1W2PQD4|A0A1W2PQD4_HUMAN,tr|A0A1W2PP34|A0A1W2PP34_HUMAN,tr|A0A1X7SBS1|A0A1X7SBS1_HUMAN" 12 1583.7601 0.46 22271 23576 2 1583.764705 792.8873 Heterogeneous nuclear ribonucleoprotein U OS=Homo sapiens OX=9606 GN=HNRNPU PE=1 SV=6 4.37 3830.7 - 1.53E+06 - - - 2.9032 - 3.222 0.7 - 669.9 1 2 0 0.0046 15 0 0 0 5.36E+07 1.16E+08 - - - 7.0863 0.9997 221125_WJC_METTL3_EV_vs_WT_F02.23577.23577.3 0.000139 17/84 K.GSVAGGAVYLVYDQELLGPSDK.S "sp|Q5XKP0|MIC13_HUMAN,tr|A0A140TA84|A0A140TA84_HUMAN,tr|K7EIR2|K7EIR2_HUMAN,tr|A0A140TA86|A0A140TA86_HUMAN" 4 2237.1216 2.9 22272 23577 3 2237.112096 746.7145 MICOS complex subunit MIC13 OS=Homo sapiens OX=9606 GN=MICOS13 PE=1 SV=1 4.03 3830.9 - 1.47E+06 - - - -4.2389 - 3.095 0.466 - 232.7 1 2 0 -0.0095 22 0 0 0 5.74E+06 1.98E+06 - - - 6.4114 1 221125_WJC_METTL3_EV_vs_WT_F02.23578.23578.3 1.44E-07 22/68 R.VPAGNWVLIEGVDQPIVK[136.11].T sp|Q15029|U5S1_HUMAN 1 1941.0815 2.39 22273 23578 3 1941.086094 648.0344 116 kDa U5 small nuclear ribonucleoprotein component OS=Homo sapiens OX=9606 GN=EFTUD2 PE=1 SV=1 4.37 3831 - 1.33E+06 - - - 2.3672 - 3.968 0.538 - 664.3 1 2 0 0.0046 18 0 0 0 2.48E+07 1.04E+07 - - - 7.9689 0.9763 221125_WJC_METTL3_EV_vs_WT_F02.23579.23579.2 0.0142 15/30 K.LAWVGDVFTATPAEPR[166.11].P sp|P48634|PRC2A_HUMAN 1 1738.8918 1.53 22274 23579 2 1738.886894 870.4532 Protein PRRC2A OS=Homo sapiens OX=9606 GN=PRRC2A PE=1 SV=3 4.37 3831.1 - 1.31E+06 - - - -2.8162 - 2.768 0.489 - 536.9 1 1 0 -0.0049 16 0 0 0 2.48E+07 1.62E+07 - - - 5.1543 1 221125_WJC_METTL3_EV_vs_WT_F02.23580.23580.2 1.38E-07 16/24 R.TDEQALLSSILAK.T "sp|Q6IAA8|LTOR1_HUMAN,tr|F5GX19|F5GX19_HUMAN,tr|F5H3Y3|F5H3Y3_HUMAN,tr|H0YFI1|H0YFI1_HUMAN,tr|F5H479|F5H479_HUMAN" 5 1387.7559 999 22275 23580 2 1387.755409 694.8852 Ragulator complex protein LAMTOR1 OS=Homo sapiens OX=9606 GN=LAMTOR1 PE=1 SV=2 4.37 3831.3 - 1.14E+06 - - - -0.3257 - 3.385 0.559 - 1142.1 1 2 0 -0.0005 13 0 0 0 6.99E+06 0.00E+00 - - - 6.2991 0.9998 221125_WJC_METTL3_EV_vs_WT_F02.23581.23581.2 8.83E-06 30-Nov R.GLPPVDFVPPIGVESR.E sp|P33908|MA1A1_HUMAN 1 1677.909 1.66 22276 23581 2 1677.909808 839.9618 "Mannosyl-oligosaccharide 1,2-alpha-mannosidase IA OS=Homo sapiens OX=9606 GN=MAN1A1 PE=1 SV=3" 4.37 3831.4 - 869038 - - - 0.4774 - 2.137 0.425 - 183.1 1 2 0 0.0008 16 0 0 0 1.78E+07 1.07E+07 - - - 4.0468 0.9996 221125_WJC_METTL3_EV_vs_WT_F02.23582.23582.3 0.0012 Sep-60 K.LFVGGLDWSTTQETLR.S "sp|Q96EP5|DAZP1_HUMAN,tr|K7EK33|K7EK33_HUMAN,tr|K7EQ55|K7EQ55_HUMAN,tr|K7EQ02|K7EQ02_HUMAN" 4 1821.9261 1.2 22277 23582 3 1821.925446 608.316 DAZ-associated protein 1 OS=Homo sapiens OX=9606 GN=DAZAP1 PE=1 SV=1 4.37 3831.5 - 860546 - - - -0.3666 - 1.837 0.345 - 63.6 1 2 0 -0.0007 16 0 0 0 5.00E+06 4.16E+06 - - - 3.9466 0.9998 221125_WJC_METTL3_EV_vs_WT_F02.23584.23584.2 1.45E-06 30-Dec R.GLPPVDFVPPIGVESR[166.11].E sp|P33908|MA1A1_HUMAN 1 1687.9173 1.66 22279 23584 2 1687.915663 844.9659 "Mannosyl-oligosaccharide 1,2-alpha-mannosidase IA OS=Homo sapiens OX=9606 GN=MAN1A1 PE=1 SV=3" 4.37 3831.8 - 583647 - - - -0.9562 - 2.2 0.492 - 254.5 1 2 0 -0.0016 16 0 0 0 1.78E+07 1.07E+07 - - - 4.6129 1 221125_WJC_METTL3_EV_vs_WT_F02.23585.23585.2 5.19E-07 13/28 K.VNAMTFTFDNVLPGK.Y "sp|Q15155|NOMO1_HUMAN,sp|Q5JPE7|NOMO2_HUMAN,sp|P69849|NOMO3_HUMAN,tr|A0A7I2V3P4|A0A7I2V3P4_HUMAN,tr|A0A7I2V6B0|A0A7I2V6B0_HUMAN,tr|A0A7I2V4D7|A0A7I2V4D7_HUMAN,tr|A0A7I2V4T6|A0A7I2V4T6_HUMAN,tr|A0A0G2JP90|A0A0G2JP90_HUMAN,tr|A0A087X117|A0A087X117_HUMAN,tr|A0A0G2JN29|A0A0G2JN29_HUMAN,tr|A0A7I2V2Z5|A0A7I2V2Z5_HUMAN,tr|H3BPS9|H3BPS9_HUMAN,tr|A0A087WW46|A0A087WW46_HUMAN,tr|J3KN36|J3KN36_HUMAN" 14 1652.8232 37.48 22280 23585 2 1652.826801 827.4189 Nodal modulator 1 OS=Homo sapiens OX=9606 GN=NOMO1 PE=1 SV=5 5.81 3831.9 - 530827 - - - 2.1612 - 2.504 0.617 - 416.6 1 2 0 0.0036 15 0 0 0 7.89E+06 2.10E+05 - - - 5.8537 0.9462 221125_WJC_METTL3_EV_vs_WT_F02.23586.23586.2 0.000363 22-Oct V.INGNPITIFQER.D sp|P04406|G3P_HUMAN 1 1400.7412 5.71 22281 23586 2 1400.745583 701.3779 Glyceraldehyde-3-phosphate dehydrogenase OS=Homo sapiens OX=9606 GN=GAPDH PE=1 SV=3 6 3832 - 505449 - - - 3.1198 - 2.082 0.432 - 210.3 1 1 0 0.0044 12 0 0 0 9.88E+06 1.73E+06 - - - 4.1599 0.9997 221125_WJC_METTL3_EV_vs_WT_F02.23587.23587.3 0.00179 Sep-52 R.GFGFVTFENIDDAK.D "sp|Q14011|CIRBP_HUMAN,tr|K7ER40|K7ER40_HUMAN,tr|K7ENX8|K7ENX8_HUMAN,tr|K7EJV1|K7EJV1_HUMAN,tr|K7EJV5|K7EJV5_HUMAN,tr|K7ELT6|K7ELT6_HUMAN,tr|K7EMY9|K7EMY9_HUMAN,tr|K7ELV6|K7ELV6_HUMAN,tr|K7EQR7|K7EQR7_HUMAN,tr|K7EPM4|K7EPM4_HUMAN,tr|D6W5Y5|D6W5Y5_HUMAN" 11 1558.7304 0.81 22282 23587 3 1558.729388 520.5841 Cold-inducible RNA-binding protein OS=Homo sapiens OX=9606 GN=CIRBP PE=1 SV=1 4.03 3832.2 - 410393 - - - -0.6326 - 1.349 0.429 - 62.3 1 2 0 -0.001 14 0 0 0 1.50E+06 1.84E+06 - - - 4.1182 0.9997 221125_WJC_METTL3_EV_vs_WT_F02.23588.23588.3 1.35E-05 Sep-48 R.TDEQALLSSILAK[136.11].T "sp|Q6IAA8|LTOR1_HUMAN,tr|F5GX19|F5GX19_HUMAN,tr|F5H3Y3|F5H3Y3_HUMAN,tr|H0YFI1|H0YFI1_HUMAN,tr|F5H479|F5H479_HUMAN" 5 1395.7701 1.32 22283 23588 3 1395.768129 466.264 Ragulator complex protein LAMTOR1 OS=Homo sapiens OX=9606 GN=LAMTOR1 PE=1 SV=2 4.37 3832.3 - 374989 - - - -1.3842 - 1.986 0.359 - 137.5 1 2 0 -0.0019 13 0 0 0 1.20E+06 9.03E+05 - - - 4.4022 1 221125_WJC_METTL3_EV_vs_WT_F02.23589.23589.3 5.77E-07 14/56 K.DC[160.03]EVVMMIGLPGAGK.T "sp|Q00839|HNRPU_HUMAN,tr|A0A1W2PQL0|A0A1W2PQL0_HUMAN,tr|A0A1W2PPL4|A0A1W2PPL4_HUMAN,tr|A0A1W2PQ74|A0A1W2PQ74_HUMAN,tr|Q5RI18|Q5RI18_HUMAN,tr|A0A1W2PP35|A0A1W2PP35_HUMAN,tr|A0A1W2PPS1|A0A1W2PPS1_HUMAN,tr|A0A1W2PRZ7|A0A1W2PRZ7_HUMAN,tr|A0A1W2PPH7|A0A1W2PPH7_HUMAN,tr|A0A1W2PQD4|A0A1W2PQD4_HUMAN,tr|A0A1W2PP34|A0A1W2PP34_HUMAN,tr|A0A1X7SBS1|A0A1X7SBS1_HUMAN" 12 1575.7459 0.71 22284 23589 3 1575.746508 526.2559 Heterogeneous nuclear ribonucleoprotein U OS=Homo sapiens OX=9606 GN=HNRNPU PE=1 SV=6 4.37 3832.4 - 368692 - - - 0.3814 - 2.848 0.509 - 258.1 1 2 0 0.0006 15 0 0 0 1.23E+07 1.73E+07 - - - 6.9457 1 221125_WJC_METTL3_EV_vs_WT_F02.23595.23595.2 3.86E-10 17/30 R.WDPTANEDPEWILVEK[136.11].D "sp|Q14257|RCN2_HUMAN,tr|A8MXP8|A8MXP8_HUMAN" 2 1948.9298 0.95 22288 23595 2 1948.923415 975.4722 Reticulocalbin-2 OS=Homo sapiens OX=9606 GN=RCN2 PE=1 SV=1 3.83 3833.2 - 1.30E+06 - - - -3.2808 - 3.011 0.664 - 838.4 1 2 0 -0.0064 16 0 0 0 1.08E+07 1.14E+07 - - - 6.6533 0.9985 221125_WJC_METTL3_EV_vs_WT_F02.23596.23596.2 3.27E-06 24-Nov K.AGVNFSEFTGVWK.Y "sp|O75340|PDCD6_HUMAN,tr|A0A024QZ42|A0A024QZ42_HUMAN" 2 1440.7038 0.77 22289 23596 2 1440.700052 721.3592 Programmed cell death protein 6 OS=Homo sapiens OX=9606 GN=PDCD6 PE=1 SV=1 6.05 3833.4 - 935639 - - - -2.5772 - 2.539 0.223 - 424 1 2 0 -0.0037 13 0 0 0 1.01E+07 1.31E+07 - - - 3.0783 0.9906 221125_WJC_METTL3_EV_vs_WT_F02.23597.23597.2 5.01E-09 24-Dec K.AGVNFSEFTGVWK[136.11].Y "sp|O75340|PDCD6_HUMAN,tr|A0A024QZ42|A0A024QZ42_HUMAN" 2 1448.718 0.77 22290 23597 2 1448.709091 725.3663 Programmed cell death protein 6 OS=Homo sapiens OX=9606 GN=PDCD6 PE=1 SV=1 6.05 3833.4 - 907403 - - - -6.1254 - 2.631 0.326 - 568 1 2 0 -0.0089 13 0 0 0 1.03E+07 1.33E+07 - - - 3.9288 0.9998 221125_WJC_METTL3_EV_vs_WT_F02.23598.23598.2 4.52E-05 20-Oct R.GVTFLFPIQAK[136.11].T sp|Q9NR30|DDX21_HUMAN 1 1227.7107 0.93 22291 23598 2 1227.710074 614.8626 Nucleolar RNA helicase 2 OS=Homo sapiens OX=9606 GN=DDX21 PE=1 SV=5 8.75 3833.5 - 600603 - - - -0.5058 - 2.09 0.384 - 402.8 1 2 0 -0.0006 11 0 0 0 1.16E+07 1.25E+07 - - - 3.8712 1 221125_WJC_METTL3_EV_vs_WT_F02.23604.23604.3 6.67E-11 16/56 K.DC[160.03]EVVMMIGLPGAGK[136.11].T "sp|Q00839|HNRPU_HUMAN,tr|A0A1W2PQL0|A0A1W2PQL0_HUMAN,tr|A0A1W2PPL4|A0A1W2PPL4_HUMAN,tr|A0A1W2PQ74|A0A1W2PQ74_HUMAN,tr|Q5RI18|Q5RI18_HUMAN,tr|A0A1W2PP35|A0A1W2PP35_HUMAN,tr|A0A1W2PPS1|A0A1W2PPS1_HUMAN,tr|A0A1W2PRZ7|A0A1W2PRZ7_HUMAN,tr|A0A1W2PPH7|A0A1W2PPH7_HUMAN,tr|A0A1W2PQD4|A0A1W2PQD4_HUMAN,tr|A0A1W2PP34|A0A1W2PP34_HUMAN,tr|A0A1X7SBS1|A0A1X7SBS1_HUMAN" 12 1583.7601 0.72 22295 23604 3 1583.762675 528.9273 Heterogeneous nuclear ribonucleoprotein U OS=Homo sapiens OX=9606 GN=HNRNPU PE=1 SV=6 4.37 3834.1 - 1.52E+06 - - - 1.6215 - 3.146 0.553 - 308.2 1 2 0 0.0026 15 0 0 0 1.24E+07 1.73E+07 - - - 7.6954 1 221125_WJC_METTL3_EV_vs_WT_F02.23605.23605.2 7.51E-09 18/30 R.WDPTANEDPEWILVEK.D "sp|Q14257|RCN2_HUMAN,tr|A8MXP8|A8MXP8_HUMAN" 2 1940.9156 0.95 22296 23605 2 1940.916329 971.4651 Reticulocalbin-2 OS=Homo sapiens OX=9606 GN=RCN2 PE=1 SV=1 3.83 3834.2 - 1.46E+06 - - - 0.371 - 3.307 0.648 - 1051.3 1 2 0 0.0007 16 0 0 0 1.08E+07 1.14E+07 - - - 6.7674 0.9998 221125_WJC_METTL3_EV_vs_WT_F02.23607.23607.2 1.21E-05 20-Dec R.GVTFLFPIQAK.T sp|Q9NR30|DDX21_HUMAN 1 1219.6965 0.93 22298 23607 2 1219.696596 610.8555 Nucleolar RNA helicase 2 OS=Homo sapiens OX=9606 GN=DDX21 PE=1 SV=5 8.75 3834.4 - 1.20E+06 - - - 0.0828 - 2.127 0.39 - 557.1 1 2 0 0.0001 11 0 0 0 1.16E+07 1.25E+07 - - - 3.9632 1 221125_WJC_METTL3_EV_vs_WT_F02.23608.23608.2 3.82E-07 18/34 K.SLTGVVNAQALTSAFSPH.T "sp|O43175|SERA_HUMAN,tr|A0A2C9F2M7|A0A2C9F2M7_HUMAN,tr|A0A286YF22|A0A286YF22_HUMAN,tr|A0A286YFL2|A0A286YFL2_HUMAN" 4 1798.9214 - 22299 23608 2 1798.922898 900.468 D-3-phosphoglycerate dehydrogenase OS=Homo sapiens OX=9606 GN=PHGDH PE=1 SV=4 6.46 3834.6 - 962971 - - - 0.8533 - 3.604 0.681 - 927.3 1 1 0 0.0015 18 0 0 0 - - - - - 7.2223 0.9999 221125_WJC_METTL3_EV_vs_WT_F02.23610.23610.3 3.30E-07 17/68 R.TVGALQVLGTEAQSSLLK.A sp|P78527|PRKDC_HUMAN 1 1814.0149 0.95 22301 23610 3 1814.020086 605.6789 DNA-dependent protein kinase catalytic subunit OS=Homo sapiens OX=9606 GN=PRKDC PE=1 SV=3 5.66 3834.8 - 536694 - - - 2.8429 - 2.751 0.478 - 272.5 1 2 0 0.0052 18 0 0 0 2.77E+06 2.92E+06 - - - 6.3877 0.9999 221125_WJC_METTL3_EV_vs_WT_F02.23611.23611.3 5.31E-05 13/56 K.APDEETLIALLAHAK[136.11].M "sp|Q9Y3E5|PTH2_HUMAN,tr|J3KQ48|J3KQ48_HUMAN" 2 1598.8759 1.25 22302 23611 3 1598.877611 533.9659 "Peptidyl-tRNA hydrolase 2, mitochondrial OS=Homo sapiens OX=9606 GN=PTRH2 PE=1 SV=1" 4.65 3835 - 439895 - - - 1.0557 - 2.335 0.413 - 243.6 1 2 0 0.0017 15 0 0 0 1.12E+07 8.97E+06 - - - 5.3568 1 221125_WJC_METTL3_EV_vs_WT_F02.23613.23613.3 6.97E-05 Dec-40 R.SIIGMIDMFHK.Y "sp|Q86SG5|S1A7A_HUMAN,sp|P31151|S10A7_HUMAN" 2 1290.6464 999 22303 23613 3 1290.646725 431.2228 Protein S100-A7A OS=Homo sapiens OX=9606 GN=S100A7A PE=1 SV=3 6.46 3835.2 - 5.51E+06 - - - 0.2131 - 2.391 0.526 - 116.9 1 2 0 0.0003 11 0 0 0 7.25E+07 0.00E+00 - - - 6.8807 0.9745 221125_WJC_METTL3_EV_vs_WT_F02.23614.23614.3 0.0259 14/68 R.TVAAPSVFIFPPSDEQLK.S "sp|P01834|IGKC_HUMAN,tr|A0A5H1ZRQ3|A0A5H1ZRQ3_HUMAN" 2 1945.0197 999 22304 23614 3 1945.028171 649.3472 Immunoglobulin kappa constant OS=Homo sapiens OX=9606 GN=IGKC PE=1 SV=2 4.37 3835.3 - 1.02E+06 - - - 4.3655 - 1.993 0.218 - 179.3 1 2 0 0.0085 18 0 0 0 1.56E+06 0.00E+00 - - - 2.6854 0.9994 221125_WJC_METTL3_EV_vs_WT_F02.23617.23617.3 0.0086 Dec-56 R.RFPVAPLIPYPLITK.E "sp|P49756|RBM25_HUMAN,tr|H0YE46|H0YE46_HUMAN" 2 1724.0389 0.8 22307 23617 3 1724.041112 575.6869 RNA-binding protein 25 OS=Homo sapiens OX=9606 GN=RBM25 PE=1 SV=3 9.99 3835.6 - 938535 - - - 1.2836 - 2.277 0.291 - 175.3 1 2 0 0.0022 15 0 0 0 9.38E+06 1.18E+07 - - - 3.9309 0.9914 221125_WJC_METTL3_EV_vs_WT_F02.23618.23618.3 1.95E-06 17/64 Y.LIDRDPTYFGPVLNYLR.H "sp|Q9NXV2|KCTD5_HUMAN,tr|H3BSS5|H3BSS5_HUMAN" 2 2051.084 3.43 22308 23618 3 2051.086894 684.7019 BTB\POZ domain-containing protein KCTD5 OS=Homo sapiens OX=9606 GN=KCTD5 PE=1 SV=1 5.96 3835.7 - 919639 - - - 1.4056 - 3.179 0.563 - 461.1 1 1 1 0.0029 17 0 0 0 1.26E+07 3.68E+06 - - - 7.7379 0.9787 221125_WJC_METTL3_EV_vs_WT_F02.23619.23619.2 0.00509 22-Sep K.GK[136.11]VPVTYLELLS.- "sp|Q9NR46|SHLB2_HUMAN,tr|B7ZC39|B7ZC39_HUMAN,tr|B7ZC38|B7ZC38_HUMAN" 3 1325.7686 1.2 22309 23619 2 1325.771642 663.8916 Endophilin-B2 OS=Homo sapiens OX=9606 GN=SH3GLB2 PE=1 SV=1 6 3835.9 - 625850 - - - 2.2915 - 1.739 0.299 - 217.6 1 2 1 0.003 12 0 0 0 6.83E+06 5.66E+06 - - - 2.7043 0.999 221125_WJC_METTL3_EV_vs_WT_F02.23621.23621.3 2.04E-05 Oct-52 K.FKLDEFYIGQIPLK.E "sp|O15047|SET1A_HUMAN,tr|A0A804HLA6|A0A804HLA6_HUMAN" 2 1709.9392 1.23 22311 23621 3 1709.942515 570.987 Histone-lysine N-methyltransferase SETD1A OS=Homo sapiens OX=9606 GN=SETD1A PE=1 SV=3 6.07 3836.1 - 525866 - - - 1.9123 - 2.064 0.41 - 110.8 1 2 1 0.0033 14 0 0 0 3.05E+06 2.49E+06 - - - 5.036 1 221125_WJC_METTL3_EV_vs_WT_F02.23622.23622.3 7.10E-07 17/92 R.TPYTMGYGESMYYNDAYGALDYYK.R sp|Q9BQ04|RBM4B_HUMAN 1 2835.172 1.86 22312 23622 3 2835.17494 946.0646 RNA-binding protein 4B OS=Homo sapiens OX=9606 GN=RBM4B PE=1 SV=1 4.03 3836.3 - 502208 - - - 1.0243 - 3.756 0.7 - 293.7 1 2 0 0.0029 24 0 0 0 3.02E+06 1.63E+06 - - - 9.4171 1 221125_WJC_METTL3_EV_vs_WT_F02.23623.23623.3 1.86E-08 19/56 K.APDEETLIALLAHAK.M "sp|Q9Y3E5|PTH2_HUMAN,tr|J3KQ48|J3KQ48_HUMAN" 2 1590.8617 1.23 22313 23623 3 1590.863606 531.2945 "Peptidyl-tRNA hydrolase 2, mitochondrial OS=Homo sapiens OX=9606 GN=PTRH2 PE=1 SV=1" 4.65 3836.4 - 493050 - - - 1.1836 - 3.013 0.558 - 710.8 1 2 0 0.0019 15 0 0 0 1.14E+07 9.27E+06 - - - 7.6386 1 221125_WJC_METTL3_EV_vs_WT_F02.23625.23625.3 1.03E-08 Dec-92 R.TPYTMGYGESMYYNDAYGALDYYK[136.11].R sp|Q9BQ04|RBM4B_HUMAN 1 2843.1862 -1 22315 23625 3 2843.184362 948.736 RNA-binding protein 4B OS=Homo sapiens OX=9606 GN=RBM4B PE=1 SV=1 4.03 3836.7 - 402923 - - - -0.6591 - 2.889 0.699 - 123.5 1 2 0 -0.0019 24 0 0 0 0.00E+00 0.00E+00 - - - 8.7967 0.9997 221125_WJC_METTL3_EV_vs_WT_F02.23626.23626.2 1.76E-06 28-Sep K.GQEYPAIVEFAPFQK.A sp|Q9BZI7|REN3B_HUMAN 1 1722.8617 0.36 22316 23626 2 1722.858348 862.4381 Regulator of nonsense transcripts 3B OS=Homo sapiens OX=9606 GN=UPF3B PE=1 SV=1 4.53 3836.8 - 298034 - - - -1.959 - 1.864 0.541 - 224.2 1 2 0 -0.0034 15 0 0 0 6.52E+06 1.79E+07 - - - 4.5668 0.8398 221125_WJC_METTL3_EV_vs_WT_F02.23628.23628.2 0.0107 Sep-34 K.TPPAVLQPIAPQTTFGVQ.T "sp|Q8IX12|CCAR1_HUMAN,tr|F5H2E6|F5H2E6_HUMAN,tr|F5H1H2|F5H1H2_HUMAN,tr|A0A0C4DGG8|A0A0C4DGG8_HUMAN,tr|F5H3E1|F5H3E1_HUMAN" 5 1864.0095 - 22318 23628 2 1864.013872 933.012 Cell division cycle and apoptosis regulator protein 1 OS=Homo sapiens OX=9606 GN=CCAR1 PE=1 SV=2 5.19 3837 - 215476 - - - 2.3723 - 1.661 0.274 - 184.4 1 1 0 0.0044 18 0 0 0 - - - - - 2.3109 1 221125_WJC_METTL3_EV_vs_WT_F02.23631.23631.2 8.55E-07 13/24 K.DFFQSYGNVVELR.L "sp|Q13283|G3BP1_HUMAN,tr|A0A7I2V5M7|A0A7I2V5M7_HUMAN,tr|A0A7I2YQN9|A0A7I2YQN9_HUMAN,tr|A0A7I2YQH0|A0A7I2YQH0_HUMAN" 4 1572.7573 0.81 22319 23631 2 1572.759548 787.3859 Ras GTPase-activating protein-binding protein 1 OS=Homo sapiens OX=9606 GN=G3BP1 PE=1 SV=1 4.37 3837.5 - 1.49E+07 - - - 1.456 - 2.762 0.661 - 576.5 1 2 0 0.0023 13 0 0 0 7.86E+07 9.72E+07 - - - 6.5299 0.9999 221125_WJC_METTL3_EV_vs_WT_F02.23632.23632.2 6.76E-08 26-Dec K.AFYPEEISSMVLTK[136.11].M "sp|P0DMV8|HS71A_HUMAN,sp|P34931|HS71L_HUMAN,sp|P0DMV9|HS71B_HUMAN,tr|Q53FA3|Q53FA3_HUMAN,tr|A0A0G2JIW1|A0A0G2JIW1_HUMAN" 5 1621.8153 0.001 22320 23632 2 1621.81616 811.9149 Heat shock 70 kDa protein 1A OS=Homo sapiens OX=9606 GN=HSPA1A PE=1 SV=1 4.53 3837.5 - 1.40E+07 - - - 0.5327 - 2.322 0.559 - 345.4 1 2 0 0.0009 14 0 0 0 0.00E+00 4.90E+08 - - - 5.2835 1 221125_WJC_METTL3_EV_vs_WT_F02.23633.23633.3 3.52E-09 17/52 R.LHFFMPGFAPLTSR[166.11].G "sp|P04350|TBB4A_HUMAN,sp|Q9BVA1|TBB2B_HUMAN,sp|A6NNZ2|TBB8B_HUMAN,sp|P07437|TBB5_HUMAN,sp|Q13885|TBB2A_HUMAN,sp|P68371|TBB4B_HUMAN,sp|Q9BUF5|TBB6_HUMAN,sp|Q3ZCM7|TBB8_HUMAN,tr|Q5ST81|Q5ST81_HUMAN,tr|Q5JP53|Q5JP53_HUMAN,tr|K7ESM5|K7ESM5_HUMAN,tr|A0A075B736|A0A075B736_HUMAN,tr|Q5SQY0|Q5SQY0_HUMAN" 13 1629.8365 0.54 22321 23633 3 1629.833231 544.2861 Tubulin beta-4A chain OS=Homo sapiens OX=9606 GN=TUBB4A PE=1 SV=2 9.76 3837.5 - 1.85E+07 - - - -2.0204 - 3.075 0.618 - 419.4 1 2 0 -0.0033 14 0 0 0 8.29E+07 1.52E+08 - - - 8.4144 1 221125_WJC_METTL3_EV_vs_WT_F02.23635.23635.3 4.46E-07 20/72 K.ILTATVDNANILLQIDNAR.L "sp|Q04695|K1C17_HUMAN,tr|K7EPJ9|K7EPJ9_HUMAN,tr|F5GWP8|F5GWP8_HUMAN" 3 2067.1324 55.1 22323 23635 3 2067.132906 690.0514 "Keratin, type I cytoskeletal 17 OS=Homo sapiens OX=9606 GN=KRT17 PE=1 SV=2" 4.21 3837.6 - 2.87E+06 - - - 0.2361 - 3.422 0.602 - 334.6 1 2 0 0.0005 19 0 0 0 5.50E+07 9.98E+05 - - - 8.274 1 221125_WJC_METTL3_EV_vs_WT_F02.23637.23637.3 1.50E-06 19/72 R.LIDWGLAEFYHPGQEYNVR.V "sp|P68400|CSK21_HUMAN,sp|Q8NEV1|CSK23_HUMAN,tr|A0A2R8YFU2|A0A2R8YFU2_HUMAN,tr|A0A2R8Y4D6|A0A2R8Y4D6_HUMAN,tr|A0A2R8YD58|A0A2R8YD58_HUMAN,tr|A0A2R8YF43|A0A2R8YF43_HUMAN,tr|A0A2R8Y4H0|A0A2R8Y4H0_HUMAN,tr|A0A2R8YDP2|A0A2R8YDP2_HUMAN,tr|E7EU96|E7EU96_HUMAN" 9 2306.112 0.97 22325 23637 3 2306.114143 769.7113 Casein kinase II subunit alpha OS=Homo sapiens OX=9606 GN=CSNK2A1 PE=1 SV=1 4.65 3837.8 - 2.62E+06 - - - 0.9219 - 3.605 0.483 - 316.1 1 2 0 0.0021 19 0 0 0 8.25E+06 8.52E+06 - - - 7.0748 0.9998 221125_WJC_METTL3_EV_vs_WT_F02.23638.23638.2 0.000168 20-Nov K.DSLVDIIGIC[160.03]K.S "sp|P27694|RFA1_HUMAN,tr|I3L4R8|I3L4R8_HUMAN" 2 1231.6482 1.35 22326 23638 2 1231.647959 616.8314 Replication protein A 70 kDa DNA-binding subunit OS=Homo sapiens OX=9606 GN=RPA1 PE=1 SV=2 4.21 3837.9 - 1.90E+06 - - - -0.216 - 1.978 0.473 - 343.2 1 2 0 -0.0003 11 0 0 0 7.41E+06 5.47E+06 - - - 4.3797 0.9999 221125_WJC_METTL3_EV_vs_WT_F02.23639.23639.2 6.87E-07 22-Dec R.LEGLTDEINFLR.Q "sp|P05787|K2C8_HUMAN,tr|F8VUG2|F8VUG2_HUMAN,tr|F8VP67|F8VP67_HUMAN,tr|F8W1U3|F8W1U3_HUMAN" 4 1418.7405 5.81 22327 23639 2 1418.739219 710.3775 "Keratin, type II cytoskeletal 8 OS=Homo sapiens OX=9606 GN=KRT8 PE=1 SV=7" 4.14 3838 - 1.76E+06 - - - -0.9346 - 2.627 0.547 - 664.6 1 2 0 -0.0013 12 0 0 0 4.25E+06 7.32E+05 - - - 5.622 1 221125_WJC_METTL3_EV_vs_WT_F02.23643.23643.2 5.30E-10 24/36 K.ILTATVDNANILLQIDNAR.L "sp|Q04695|K1C17_HUMAN,tr|K7EPJ9|K7EPJ9_HUMAN,tr|F5GWP8|F5GWP8_HUMAN" 3 2067.1324 999 22331 23643 2 2067.130474 1034.5735 "Keratin, type I cytoskeletal 17 OS=Homo sapiens OX=9606 GN=KRT17 PE=1 SV=2" 4.21 3838.5 - 1.60E+06 - - - -0.9404 - 4.149 0.587 - 2130.4 1 2 0 -0.0019 19 0 0 0 1.37E+07 0.00E+00 - - - 6.8742 1 221125_WJC_METTL3_EV_vs_WT_F02.23649.23649.2 9.61E-13 17/28 K.TTGFGMIYDSLDYAK[136.11].K "sp|P62847|RS24_HUMAN,tr|A0A2R8YD14|A0A2R8YD14_HUMAN,tr|A0A2R8Y849|A0A2R8Y849_HUMAN,tr|A0A2R8Y8A0|A0A2R8Y8A0_HUMAN,tr|E7ETK0|E7ETK0_HUMAN" 5 1688.7847 0.92 22337 23649 2 1688.786628 845.3996 40S ribosomal protein S24 OS=Homo sapiens OX=9606 GN=RPS24 PE=1 SV=1 4.21 3839.3 - 817481 - - - 1.1274 - 3.268 0.665 - 1051.5 1 2 0 0.0019 15 0 0 0 2.65E+07 2.88E+07 - - - 6.8634 1 221125_WJC_METTL3_EV_vs_WT_F02.23650.23650.3 9.99E-07 13/52 K.TFAPEEISAMVLTK[136.11].M "sp|P11021|BIP_HUMAN,tr|A0A7P0TB36|A0A7P0TB36_HUMAN,tr|A0A7P0TAI0|A0A7P0TAI0_HUMAN" 3 1543.8047 0.46 22338 23650 3 1543.80245 515.6089 Endoplasmic reticulum chaperone BiP OS=Homo sapiens OX=9606 GN=HSPA5 PE=1 SV=2 4.53 3839.4 - 813231 - - - -1.4782 - 2.399 0.505 - 282.5 1 2 0 -0.0023 14 0 0 0 1.74E+06 3.79E+06 - - - 6.4951 0.9995 221125_WJC_METTL3_EV_vs_WT_F02.23653.23653.3 2.85E-05 Dec-64 K.SLFAHDDSVMYLQFVPK[136.11].S sp|Q9UNX4|WDR3_HUMAN 1 2003.9906 -1 22340 23653 3 2003.991473 669.0042 WD repeat-containing protein 3 OS=Homo sapiens OX=9606 GN=WDR3 PE=1 SV=1 5.19 3839.7 - 579162 - - - 0.4182 - 2.271 0.293 - 139.3 1 2 0 0.0008 17 0 0 0 0.00E+00 0.00E+00 - - - 3.8786 1 221125_WJC_METTL3_EV_vs_WT_F02.23654.23654.2 5.65E-10 17/28 K.TTGFGMIYDSLDYAK.K "sp|P62847|RS24_HUMAN,tr|A0A2R8YD14|A0A2R8YD14_HUMAN,tr|A0A2R8Y849|A0A2R8Y849_HUMAN,tr|A0A2R8Y8A0|A0A2R8Y8A0_HUMAN,tr|E7ETK0|E7ETK0_HUMAN" 5 1680.7705 0.92 22341 23654 2 1680.770792 841.3925 40S ribosomal protein S24 OS=Homo sapiens OX=9606 GN=RPS24 PE=1 SV=1 4.21 3839.8 - 2.93E+06 - - - 0.1595 - 3.202 0.612 - 1184.8 1 2 0 0.0003 15 0 0 0 2.65E+07 2.88E+07 - - - 6.4223 1 221125_WJC_METTL3_EV_vs_WT_F02.23656.23656.3 6.58E-07 Dec-64 R.AVC[160.03]MLSNTTAIAEAWAR[166.11].L "sp|Q9NY65|TBA8_HUMAN,sp|Q6PEY2|TBA3E_HUMAN,sp|P0DPH7|TBA3C_HUMAN,sp|Q71U36|TBA1A_HUMAN,sp|P0DPH8|TBA3D_HUMAN,sp|P68366|TBA4A_HUMAN,sp|P68363|TBA1B_HUMAN,tr|C9J2C0|C9J2C0_HUMAN,tr|V9GZ17|V9GZ17_HUMAN,tr|A0A7P0T945|A0A7P0T945_HUMAN" 10 1873.9054 0.53 22343 23656 3 1873.905375 625.6424 Tubulin alpha-8 chain OS=Homo sapiens OX=9606 GN=TUBA8 PE=1 SV=1 6.04 3839.9 - 2.15E+06 - - - -0.0181 - 2.578 0.51 - 164.8 1 2 0 0 17 0 0 0 3.56E+07 6.75E+07 - - - 6.6184 1 221125_WJC_METTL3_EV_vs_WT_F02.23660.23660.2 4.15E-07 21/32 R.AVC[160.03]MLSNTTAIAEAWAR[166.11].L "sp|Q9NY65|TBA8_HUMAN,sp|Q6PEY2|TBA3E_HUMAN,sp|P0DPH7|TBA3C_HUMAN,sp|Q71U36|TBA1A_HUMAN,sp|P0DPH8|TBA3D_HUMAN,sp|P68366|TBA4A_HUMAN,sp|P68363|TBA1B_HUMAN,tr|C9J2C0|C9J2C0_HUMAN,tr|V9GZ17|V9GZ17_HUMAN,tr|A0A7P0T945|A0A7P0T945_HUMAN" 10 1873.9054 0.5 22347 23660 2 1873.906422 937.96 Tubulin alpha-8 chain OS=Homo sapiens OX=9606 GN=TUBA8 PE=1 SV=1 6.04 3840.3 - 1.54E+06 - - - 0.5406 - 3.703 0.68 - 1446.1 1 2 0 0.001 17 0 0 0 2.75E+07 5.47E+07 - - - 7.2818 0.9996 221125_WJC_METTL3_EV_vs_WT_F02.23661.23661.2 0.0529 20-Oct R.SIIGMIDMFHK.Y "sp|Q86SG5|S1A7A_HUMAN,sp|P31151|S10A7_HUMAN" 2 1290.6464 7.41 22348 23661 2 1290.646559 646.3305 Protein S100-A7A OS=Homo sapiens OX=9606 GN=S100A7A PE=1 SV=3 6.46 3840.3 - 1.49E+06 - - - 0.0845 - 1.897 0.325 - 282.7 1 2 0 0.0001 11 0 0 0 1.78E+07 2.41E+06 - - - 3.1735 0.9988 221125_WJC_METTL3_EV_vs_WT_F02.23663.23663.2 1.68E-05 24-Dec R.TDDIPVWDQEFLK.V "sp|P63208|SKP1_HUMAN,tr|E5RGM3|E5RGM3_HUMAN,tr|E5RJR5|E5RJR5_HUMAN,tr|E7ERH2|E7ERH2_HUMAN,tr|F8W8N3|F8W8N3_HUMAN" 5 1604.7722 1.38 22350 23663 2 1604.775195 803.3934 S-phase kinase-associated protein 1 OS=Homo sapiens OX=9606 GN=SKP1 PE=1 SV=2 3.84 3840.5 - 1.34E+06 - - - 1.842 - 1.919 0.299 - 367.6 1 2 0 0.003 13 0 0 0 2.25E+07 1.63E+07 - - - 2.9214 1 221125_WJC_METTL3_EV_vs_WT_F02.23666.23666.3 1.82E-10 18/72 K.MEDTLVNNVPLPNTLPLPK.R "sp|Q9Y520|PRC2C_HUMAN,tr|E7EPN9|E7EPN9_HUMAN,tr|A0A2R8Y7F4|A0A2R8Y7F4_HUMAN,tr|A0A2R8YET2|A0A2R8YET2_HUMAN" 4 2104.1238 9.74 22353 23666 3 2104.124106 702.3819 Protein PRRC2C OS=Homo sapiens OX=9606 GN=PRRC2C PE=1 SV=4 4.37 3840.8 - 1.01E+06 - - - 0.1326 - 3.206 0.645 - 370.4 1 2 0 0.0003 19 0 0 0 7.76E+06 7.97E+05 - - - 8.5933 1 221125_WJC_METTL3_EV_vs_WT_F02.23667.23667.2 1.83E-10 14/30 K.AYLPVNESFGFTADLR[166.11].S sp|P13639|EF2_HUMAN 1 1808.8973 0.57 22354 23667 2 1808.895684 905.4559 Elongation factor 2 OS=Homo sapiens OX=9606 GN=EEF2 PE=1 SV=4 4.37 3840.9 - 1.01E+06 - - - -0.8768 - 2.939 0.675 - 542.6 1 2 0 -0.0016 16 0 0 0 8.06E+06 1.42E+07 - - - 6.6765 1 221125_WJC_METTL3_EV_vs_WT_F02.23668.23668.3 4.24E-07 14/64 R.AVC[160.03]MLSNTTAIAEAWAR.L "sp|Q9NY65|TBA8_HUMAN,sp|Q6PEY2|TBA3E_HUMAN,sp|P0DPH7|TBA3C_HUMAN,sp|Q71U36|TBA1A_HUMAN,sp|P0DPH8|TBA3D_HUMAN,sp|P68366|TBA4A_HUMAN,sp|P68363|TBA1B_HUMAN,tr|C9J2C0|C9J2C0_HUMAN,tr|V9GZ17|V9GZ17_HUMAN,tr|A0A7P0T945|A0A7P0T945_HUMAN" 10 1863.8971 0.53 22355 23668 3 1863.898739 622.3063 Tubulin alpha-8 chain OS=Homo sapiens OX=9606 GN=TUBA8 PE=1 SV=1 6.04 3841 - 963185 - - - 0.8584 - 2.789 0.537 - 294 1 2 0 0.0016 17 0 0 0 3.56E+07 6.75E+07 - - - 7.1178 0.9998 221125_WJC_METTL3_EV_vs_WT_F02.23669.23669.2 0.000205 22-Oct K.TDLVPAFQNLMK[136.11].D "sp|P30153|2AAA_HUMAN,tr|C9J9C1|C9J9C1_HUMAN,tr|B3KQV6|B3KQV6_HUMAN" 3 1383.7312 0.81 22356 23669 2 1383.73154 692.8729 Serine\threonine-protein phosphatase 2A 65 kDa regulatory subunit A alpha isoform OS=Homo sapiens OX=9606 GN=PPP2R1A PE=1 SV=4 5.5 3841.1 - 953113 - - - 0.2652 - 2.037 0.403 - 281 1 2 0 0.0004 12 0 0 0 8.61E+06 1.07E+07 - - - 3.8895 1 221125_WJC_METTL3_EV_vs_WT_F02.23670.23670.2 3.43E-08 13/30 R.VIFLEDDDVAAVVDGR.L "sp|Q06210|GFPT1_HUMAN,tr|A0A6I8PRN4|A0A6I8PRN4_HUMAN,tr|A0A6I8PTT9|A0A6I8PTT9_HUMAN" 3 1731.8679 1.28 22357 23670 2 1731.871107 866.9412 Glutamine--fructose-6-phosphate aminotransferase [isomerizing] 1 OS=Homo sapiens OX=9606 GN=GFPT1 PE=1 SV=3 3.71 3841.3 - 908900 - - - 1.8344 - 2.932 0.58 - 437.8 1 2 0 0.0032 16 0 0 0 1.07E+07 8.37E+06 - - - 5.9685 1 221125_WJC_METTL3_EV_vs_WT_F02.23673.23673.3 2.18E-06 13/56 R.ALTVPELTQQVFDAK[136.11].N "sp|P07437|TBB5_HUMAN,tr|Q5ST81|Q5ST81_HUMAN,tr|Q5JP53|Q5JP53_HUMAN" 3 1666.9021 0.58 22359 23673 3 1666.904639 556.6413 Tubulin beta chain OS=Homo sapiens OX=9606 GN=TUBB PE=1 SV=2 4.37 3841.6 - 1.40E+07 - - - 1.501 - 2.678 0.518 - 261.9 1 2 0 0.0025 15 0 0 0 2.85E+07 4.94E+07 - - - 6.8849 1 221125_WJC_METTL3_EV_vs_WT_F02.23675.23675.3 9.81E-09 19/64 K.IIHDFPQFYPLGIVQHD.- "sp|P35244|RFA3_HUMAN,tr|B5MC59|B5MC59_HUMAN" 2 2038.0312 - 22361 23675 3 2038.03363 680.351 Replication protein A 14 kDa subunit OS=Homo sapiens OX=9606 GN=RPA3 PE=1 SV=1 5.22 3841.8 - 1.50E+07 - - - 1.1688 - 3.743 0.565 - 620.4 1 2 0 0.0024 17 0 0 0 - - - - - 8.173 1 221125_WJC_METTL3_EV_vs_WT_F02.23678.23678.2 8.09E-10 14/26 R.GTAYVVYEDIFDAK.N sp|Q9Y3B4|SF3B6_HUMAN 1 1589.7613 1.16 22364 23678 2 1589.762166 795.8879 Splicing factor 3B subunit 6 OS=Homo sapiens OX=9606 GN=SF3B6 PE=1 SV=1 4.03 3842.1 - 2.25E+06 - - - 0.5196 - 2.821 0.605 - 630.5 1 2 0 0.0008 14 0 0 0 2.87E+07 2.49E+07 - - - 6.1118 0.9998 221125_WJC_METTL3_EV_vs_WT_F02.23679.23679.3 7.98E-07 16/52 R.GTAYVVYEDIFDAK.N sp|Q9Y3B4|SF3B6_HUMAN 1 1589.7613 1.35 22365 23679 3 1589.767182 530.9277 Splicing factor 3B subunit 6 OS=Homo sapiens OX=9606 GN=SF3B6 PE=1 SV=1 4.03 3842.2 - 2.13E+06 - - - 3.6748 - 2.573 0.5 - 255.5 1 2 0 0.0058 14 0 0 0 2.14E+07 1.58E+07 - - - 6.6244 1 221125_WJC_METTL3_EV_vs_WT_F02.23680.23680.2 1.01E-08 16/26 R.GTAYVVYEDIFDAK[136.11].N sp|Q9Y3B4|SF3B6_HUMAN 1 1597.7755 1.17 22366 23680 2 1597.776214 799.895 Splicing factor 3B subunit 6 OS=Homo sapiens OX=9606 GN=SF3B6 PE=1 SV=1 4.03 3842.3 - 2.07E+06 - - - 0.4218 - 3.032 0.677 - 887.4 1 2 0 0.0007 14 0 0 0 2.86E+07 2.45E+07 - - - 6.8246 1 221125_WJC_METTL3_EV_vs_WT_F02.23681.23681.3 1.29E-05 15/60 K.AYLPVNESFGFTADLR[166.11].S sp|P13639|EF2_HUMAN 1 1808.8973 0.56 22367 23681 3 1808.896258 603.973 Elongation factor 2 OS=Homo sapiens OX=9606 GN=EEF2 PE=1 SV=4 4.37 3842.4 - 1.79E+06 - - - -0.5595 - 2.664 0.46 - 274 1 2 0 -0.001 16 0 0 0 3.91E+06 6.92E+06 - - - 6.1824 1 221125_WJC_METTL3_EV_vs_WT_F02.23682.23682.3 1.11E-08 13/52 R.GTAYVVYEDIFDAK[136.11].N sp|Q9Y3B4|SF3B6_HUMAN 1 1597.7755 1.35 22368 23682 3 1597.77896 533.5991 Splicing factor 3B subunit 6 OS=Homo sapiens OX=9606 GN=SF3B6 PE=1 SV=1 4.03 3842.4 - 1.71E+06 - - - 2.1405 - 2.34 0.599 - 159.8 1 2 0 0.0034 14 0 0 0 2.13E+07 1.58E+07 - - - 7.4766 0.9895 221125_WJC_METTL3_EV_vs_WT_F02.23683.23683.2 2.59E-06 14/22 K.K[136.11]VSQEILELLNT.T "sp|Q86U44|MTA70_HUMAN,tr|H0YFV6|H0YFV6_HUMAN" 2 1393.7908 0.02 22369 23683 2 1393.792258 697.9027 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 4.53 3842.5 - 1.64E+06 - - - 1.0489 - 2.573 0.432 - 647.5 1 1 0 0.0015 12 0 0 0 3.58E+06 2.08E+08 - - - 4.7179 0.9997 221125_WJC_METTL3_EV_vs_WT_F02.23685.23685.3 0.00265 Nov-56 K.TTGFGMIYDSLDYAK[136.11].K "sp|P62847|RS24_HUMAN,tr|A0A2R8YD14|A0A2R8YD14_HUMAN,tr|A0A2R8Y849|A0A2R8Y849_HUMAN,tr|A0A2R8Y8A0|A0A2R8Y8A0_HUMAN,tr|E7ETK0|E7ETK0_HUMAN" 5 1688.7847 0.46 22371 23685 3 1688.787013 563.9355 40S ribosomal protein S24 OS=Homo sapiens OX=9606 GN=RPS24 PE=1 SV=1 4.21 3842.7 - 1.16E+06 - - - 1.3554 - 1.9 0.372 - 123 1 2 0 0.0023 15 0 0 0 1.28E+06 2.80E+06 - - - 4.3616 1 221125_WJC_METTL3_EV_vs_WT_F02.23686.23686.3 0.000107 15/60 K.AYLPVNESFGFTADLR.S sp|P13639|EF2_HUMAN 1 1798.889 0.56 22372 23686 3 1798.889301 600.6369 Elongation factor 2 OS=Homo sapiens OX=9606 GN=EEF2 PE=1 SV=4 4.37 3842.8 - 868602 - - - 0.1673 - 2.776 0.467 - 299.2 1 2 0 0.0003 16 0 0 0 3.91E+06 6.92E+06 - - - 6.3663 1 221125_WJC_METTL3_EV_vs_WT_F02.23687.23687.2 3.37E-10 19/32 K.IIHDFPQFYPLGIVQHD.- "sp|P35244|RFA3_HUMAN,tr|B5MC59|B5MC59_HUMAN" 2 2038.0312 - 22373 23687 2 2038.034429 1020.0229 Replication protein A 14 kDa subunit OS=Homo sapiens OX=9606 GN=RPA3 PE=1 SV=1 5.22 3843 - 742491 - - - 1.5608 - 3.684 0.697 - 1158.4 1 2 0 0.0032 17 0 0 0 - - - - - 7.394 1 221125_WJC_METTL3_EV_vs_WT_F02.23689.23689.2 2.05E-09 16/36 R.ISGVGIDQPPYGIFVINQK.T sp|Q02413|DSG1_HUMAN 1 2044.0993 999 22375 23689 2 2044.098148 1023.0569 Desmoglein-1 OS=Homo sapiens OX=9606 GN=DSG1 PE=1 SV=2 5.83 3843.2 - 269120 - - - -0.5768 - 3.291 0.647 - 563.9 1 2 0 -0.0012 19 0 0 0 1.28E+07 0.00E+00 - - - 6.748 0.9999 221125_WJC_METTL3_EV_vs_WT_F02.23694.23694.3 7.39E-05 Nov-60 R.TMQNLEIELQSQLSMK.A sp|P02533|K1C14_HUMAN 1 1891.9383 30.5 22378 23694 3 1891.940296 631.6534 "Keratin, type I cytoskeletal 14 OS=Homo sapiens OX=9606 GN=KRT14 PE=1 SV=4" 4.53 3843.8 - 9.56E+06 - - - 1.0365 - 2.382 0.406 - 150.1 1 2 0 0.002 16 0 0 0 5.23E+07 1.71E+06 - - - 5.293 0.9998 221125_WJC_METTL3_EV_vs_WT_F02.23696.23696.3 2.40E-06 17/60 K.TLNDELEIIEGMK[136.11]FDR[166.11].G "sp|P10809|CH60_HUMAN,tr|A0A7I2V2X6|A0A7I2V2X6_HUMAN,tr|A0A7I2V599|A0A7I2V599_HUMAN,tr|E7EXB4|E7EXB4_HUMAN,tr|A0A7I2YQ71|A0A7I2YQ71_HUMAN,tr|E7ESH4|E7ESH4_HUMAN,tr|A0A7I2V5M1|A0A7I2V5M1_HUMAN,tr|A0A7I2V5K3|A0A7I2V5K3_HUMAN,tr|A0A7I2V369|A0A7I2V369_HUMAN" 9 1939.968 1.17 22380 23696 3 1939.968902 647.6633 "60 kDa heat shock protein, mitochondrial OS=Homo sapiens OX=9606 GN=HSPD1 PE=1 SV=2" 4.18 3843.9 - 6.19E+06 - - - 0.4655 - 2.865 0.441 - 225.2 1 2 1 0.0009 16 0 0 0 4.03E+07 3.44E+07 - - - 6.1572 0.9997 221125_WJC_METTL3_EV_vs_WT_F02.23697.23697.3 1.36E-05 13/60 K.TLNDELEIIEGMKFDR.G "sp|P10809|CH60_HUMAN,tr|A0A7I2V2X6|A0A7I2V2X6_HUMAN,tr|A0A7I2V599|A0A7I2V599_HUMAN,tr|E7EXB4|E7EXB4_HUMAN,tr|A0A7I2YQ71|A0A7I2YQ71_HUMAN,tr|E7ESH4|E7ESH4_HUMAN,tr|A0A7I2V5M1|A0A7I2V5M1_HUMAN,tr|A0A7I2V5K3|A0A7I2V5K3_HUMAN,tr|A0A7I2V369|A0A7I2V369_HUMAN" 9 1921.9455 1.17 22381 23697 3 1921.946669 641.6558 "60 kDa heat shock protein, mitochondrial OS=Homo sapiens OX=9606 GN=HSPD1 PE=1 SV=2" 4.18 3843.9 - 5.90E+06 - - - 0.5931 - 2.572 0.41 - 129.2 1 2 1 0.0011 16 0 0 0 4.03E+07 3.44E+07 - - - 5.5347 1 221125_WJC_METTL3_EV_vs_WT_F02.23700.23700.2 2.28E-06 16/28 R.AVFVDLEPTVIDEVR[166.11].T "sp|Q71U36|TBA1A_HUMAN,sp|P68363|TBA1B_HUMAN,sp|Q9BQE3|TBA1C_HUMAN,tr|F8VS66|F8VS66_HUMAN,tr|F8VWV9|F8VWV9_HUMAN,tr|F8VRZ4|F8VRZ4_HUMAN,tr|F8VVB9|F8VVB9_HUMAN,tr|A0A1W2PQM2|A0A1W2PQM2_HUMAN,tr|F5H5D3|F5H5D3_HUMAN,tr|F8VRK0|F8VRK0_HUMAN,tr|F8VQQ4|F8VQQ4_HUMAN,tr|F8VX09|F8VX09_HUMAN" 12 1710.9068 0.75 22384 23700 2 1710.908186 856.4607 Tubulin alpha-1A chain OS=Homo sapiens OX=9606 GN=TUBA1A PE=1 SV=1 3.92 3844.1 - 2.11E+06 - - - 0.8265 - 3.303 0.538 - 674.8 1 2 0 0.0014 15 0 0 0 7.17E+06 9.53E+06 - - - 5.9518 1 221125_WJC_METTL3_EV_vs_WT_F02.23702.23702.2 7.17E-09 19/30 R.TMQNLEIELQSQLSMK.A sp|P02533|K1C14_HUMAN 1 1891.9383 7.35 22386 23702 2 1891.936863 946.9764 "Keratin, type I cytoskeletal 14 OS=Homo sapiens OX=9606 GN=KRT14 PE=1 SV=4" 4.53 3844.3 - 1.85E+06 - - - -0.778 - 3.719 0.652 - 1714.9 1 2 0 -0.0015 16 0 0 0 1.27E+07 1.73E+06 - - - 7.0854 1 221125_WJC_METTL3_EV_vs_WT_F02.23703.23703.3 0.000101 14/56 R.DYLHLPPEIVPATLR[166.11].R "sp|P46783|RS10_HUMAN,tr|A0A2R8Y6L3|A0A2R8Y6L3_HUMAN,tr|F6U211|F6U211_HUMAN,tr|A0A1W2PQS6|A0A1W2PQS6_HUMAN,tr|A0A2R8YFH6|A0A2R8YFH6_HUMAN,tr|A0A2R8Y7H1|A0A2R8Y7H1_HUMAN,tr|S4R435|S4R435_HUMAN" 7 1742.9595 1.41 22387 23703 3 1742.960437 581.9938 40S ribosomal protein S10 OS=Homo sapiens OX=9606 GN=RPS10 PE=1 SV=1 5.32 3844.4 - 1.67E+06 - - - 0.5514 - 2.659 0.519 - 209.9 1 2 0 0.001 15 0 0 0 1.30E+07 9.26E+06 - - - 6.8779 1 221125_WJC_METTL3_EV_vs_WT_F02.23705.23705.3 0.000479 Dec-56 R.AVFVDLEPTVIDEVR[166.11].T "sp|Q71U36|TBA1A_HUMAN,sp|P68363|TBA1B_HUMAN,sp|Q9BQE3|TBA1C_HUMAN,tr|F8VS66|F8VS66_HUMAN,tr|F8VWV9|F8VWV9_HUMAN,tr|F8VRZ4|F8VRZ4_HUMAN,tr|F8VVB9|F8VVB9_HUMAN,tr|A0A1W2PQM2|A0A1W2PQM2_HUMAN,tr|F5H5D3|F5H5D3_HUMAN,tr|F8VRK0|F8VRK0_HUMAN,tr|F8VQQ4|F8VQQ4_HUMAN,tr|F8VX09|F8VX09_HUMAN" 12 1710.9068 0.61 22389 23705 3 1710.90753 571.3095 Tubulin alpha-1A chain OS=Homo sapiens OX=9606 GN=TUBA1A PE=1 SV=1 3.92 3844.6 - 1.38E+06 - - - 0.443 - 2.537 0.472 - 246.6 1 2 0 0.0008 15 0 0 0 2.67E+06 4.36E+06 - - - 6.2314 1 221125_WJC_METTL3_EV_vs_WT_F02.23706.23706.2 1.33E-13 17/34 R.IEIESFYEGEDFSETLTR[166.11].A "sp|P11021|BIP_HUMAN,tr|A0A7P0TB36|A0A7P0TB36_HUMAN,tr|A0A7P0TAI0|A0A7P0TAI0_HUMAN" 3 2173.9931 0.54 22390 23706 2 2173.99167 1088.0038 Endoplasmic reticulum chaperone BiP OS=Homo sapiens OX=9606 GN=HSPA5 PE=1 SV=2 3.83 3844.7 - 1.30E+06 - - - -0.649 - 3.605 0.697 - 746.6 1 2 0 -0.0014 18 0 0 0 4.50E+06 8.39E+06 - - - 7.3412 1 221125_WJC_METTL3_EV_vs_WT_F02.23707.23707.3 2.58E-09 22/88 K.FMTPVIQDNPSGWGPC[160.03]AVPEQFR.D "sp|O15371|EIF3D_HUMAN,tr|B0QYA8|B0QYA8_HUMAN,tr|B0QYA6|B0QYA6_HUMAN,tr|B0QYA5|B0QYA5_HUMAN" 4 2632.2203 1 22391 23707 3 2632.22234 878.414 Eukaryotic translation initiation factor 3 subunit D OS=Homo sapiens OX=9606 GN=EIF3D PE=1 SV=1 4.37 3844.8 - 1.28E+06 - - - 0.7887 - 3.339 0.425 - 338 1 2 0 0.0021 23 0 0 0 8.67E+06 8.64E+06 - - - 6.1062 1 221125_WJC_METTL3_EV_vs_WT_F02.23709.23709.2 6.17E-07 16/28 R.AVFVDLEPTVIDEVR.T "sp|Q71U36|TBA1A_HUMAN,sp|P68363|TBA1B_HUMAN,sp|Q9BQE3|TBA1C_HUMAN,tr|F8VS66|F8VS66_HUMAN,tr|F8VWV9|F8VWV9_HUMAN,tr|F8VRZ4|F8VRZ4_HUMAN,tr|F8VVB9|F8VVB9_HUMAN,tr|A0A1W2PQM2|A0A1W2PQM2_HUMAN,tr|F5H5D3|F5H5D3_HUMAN,tr|F8VRK0|F8VRK0_HUMAN,tr|F8VQQ4|F8VQQ4_HUMAN,tr|F8VX09|F8VX09_HUMAN" 12 1700.8985 0.75 22393 23709 2 1700.899132 851.4565 Tubulin alpha-1A chain OS=Homo sapiens OX=9606 GN=TUBA1A PE=1 SV=1 3.92 3845.1 - 1.19E+06 - - - 0.3704 - 3.166 0.585 - 672.4 1 2 0 0.0006 15 0 0 0 7.17E+06 9.53E+06 - - - 6.195 0.9999 221125_WJC_METTL3_EV_vs_WT_F02.23710.23710.3 6.98E-07 17/56 K.GFHQVPFAPIVFIER.T "sp|P47897|SYQ_HUMAN,tr|B4DDN1|B4DDN1_HUMAN,tr|H7C0R3|H7C0R3_HUMAN,tr|A0A0U1RQX5|A0A0U1RQX5_HUMAN,tr|A0A1B0GVU9|A0A1B0GVU9_HUMAN,tr|A0A0U1RRC8|A0A0U1RRC8_HUMAN" 6 1755.9461 1.35 22394 23710 3 1755.951609 586.3226 Glutamine--tRNA ligase OS=Homo sapiens OX=9606 GN=QARS1 PE=1 SV=1 6.75 3845.2 - 1.10E+06 - - - 3.1596 - 3.036 0.528 - 441.1 1 2 0 0.0055 15 0 0 0 1.71E+07 1.26E+07 - - - 7.3229 1 221125_WJC_METTL3_EV_vs_WT_F02.23711.23711.2 1.17E-08 18/34 R.ELAEATGLTTTQVSNWFK.N "sp|Q9NPC8|SIX2_HUMAN,sp|Q15475|SIX1_HUMAN" 2 1994.9949 -1 22395 23711 2 1994.994573 998.5047 Homeobox protein SIX2 OS=Homo sapiens OX=9606 GN=SIX2 PE=1 SV=1 4.53 3845.3 - 801696 - - - -0.1749 - 3.207 0.582 - 480.7 1 2 0 -0.0003 18 0 0 0 0.00E+00 0.00E+00 - - - 6.2046 0.9995 221125_WJC_METTL3_EV_vs_WT_F02.23712.23712.2 5.04E-06 15/34 K.LLSEEVFDFSSGQITQVK.S "sp|O14980|XPO1_HUMAN,tr|A0A7I2V488|A0A7I2V488_HUMAN,tr|A0A7I2V461|A0A7I2V461_HUMAN,tr|A0A7I2V3N0|A0A7I2V3N0_HUMAN,tr|A0A7I2V4A3|A0A7I2V4A3_HUMAN,tr|C9JKM9|C9JKM9_HUMAN,tr|A0A7I2V3W6|A0A7I2V3W6_HUMAN,tr|A0A7I2YQV4|A0A7I2YQV4_HUMAN,tr|A0A7I2YQX3|A0A7I2YQX3_HUMAN,tr|A0A7I2V2Y6|A0A7I2V2Y6_HUMAN,tr|A0A7I2V6B9|A0A7I2V6B9_HUMAN,tr|A0A7I2V3P3|A0A7I2V3P3_HUMAN,tr|A0A7I2V2S3|A0A7I2V2S3_HUMAN" 13 2026.0259 -1 22396 23712 2 2026.030585 1014.0202 Exportin-1 OS=Homo sapiens OX=9606 GN=XPO1 PE=1 SV=1 4.14 3845.4 - 720417 - - - 2.3183 - 2.047 0.471 - 500.8 1 2 0 0.0047 18 0 0 0 0.00E+00 0.00E+00 - - - 4.2796 0.9999 221125_WJC_METTL3_EV_vs_WT_F02.23715.23715.2 1.26E-08 15/26 K.TGAAGAEALSLLLK.R "sp|Q9P2N6|KANL3_HUMAN,tr|C9J5A4|C9J5A4_HUMAN,tr|A0A590UJ53|A0A590UJ53_HUMAN" 3 1313.7555 1.43 22398 23715 2 1313.755903 657.885 KAT8 regulatory NSL complex subunit 3 OS=Homo sapiens OX=9606 GN=KANSL3 PE=1 SV=2 5.66 3845.8 - 352666 - - - 0.3319 - 2.916 0.49 - 645.4 1 2 0 0.0004 14 0 0 0 1.57E+06 1.10E+06 - - - 5.3456 1 221125_WJC_METTL3_EV_vs_WT_F02.23718.23718.2 2.94E-08 18/32 R.AVC[160.03]MLSNTTAIAEAWAR.L "sp|Q9NY65|TBA8_HUMAN,sp|Q6PEY2|TBA3E_HUMAN,sp|P0DPH7|TBA3C_HUMAN,sp|Q71U36|TBA1A_HUMAN,sp|P0DPH8|TBA3D_HUMAN,sp|P68366|TBA4A_HUMAN,sp|P68363|TBA1B_HUMAN,tr|C9J2C0|C9J2C0_HUMAN,tr|V9GZ17|V9GZ17_HUMAN,tr|A0A7P0T945|A0A7P0T945_HUMAN" 10 1863.8971 0.5 22401 23718 2 1863.897864 932.9558 Tubulin alpha-8 chain OS=Homo sapiens OX=9606 GN=TUBA8 PE=1 SV=1 6.04 3846 - 2.86E+06 - - - 0.389 - 3.618 0.664 - 1062.8 1 2 0 0.0007 17 0 0 0 2.75E+07 5.47E+07 - - - 7.1066 1 221125_WJC_METTL3_EV_vs_WT_F02.23720.23720.2 1.42E-08 14/28 K.FILPNVSTPVSDAFK.T sp|Q9P2D1|CHD7_HUMAN 1 1633.8716 1.15 22403 23720 2 1633.871484 817.9431 Chromodomain-helicase-DNA-binding protein 7 OS=Homo sapiens OX=9606 GN=CHD7 PE=1 SV=3 5.84 3846.2 - 2.49E+06 - - - -0.0459 - 2.537 0.684 - 575.6 1 2 0 -0.0001 15 0 0 0 1.46E+07 1.26E+07 - - - 6.3819 1 221125_WJC_METTL3_EV_vs_WT_F02.23722.23722.3 1.16E-09 25/60 R.IPDEIIDMVKEEVVAK.G "sp|Q9Y4Z0|LSM4_HUMAN,tr|U3KQK1|U3KQK1_HUMAN,tr|V9GZ56|V9GZ56_HUMAN" 3 1826.97 1.82 22405 23722 3 1826.975455 609.9973 U6 snRNA-associated Sm-like protein LSm4 OS=Homo sapiens OX=9606 GN=LSM4 PE=1 SV=1 4.18 3846.4 - 1.38E+06 - - - 3.0115 - 4.212 0.659 - 1235.5 1 2 1 0.0055 16 0 0 0 1.30E+07 7.18E+06 - - - 9.5752 1 221125_WJC_METTL3_EV_vs_WT_F02.23723.23723.3 6.39E-09 23/72 R.LIDWGLAEFYHPAQEYNVR.V "sp|P19784|CSK22_HUMAN,tr|H3BNI9|H3BNI9_HUMAN,tr|H3BSA1|H3BSA1_HUMAN" 3 2320.1277 1.4 22406 23723 3 2320.130576 774.3832 Casein kinase II subunit alpha' OS=Homo sapiens OX=9606 GN=CSNK2A2 PE=1 SV=1 4.65 3846.5 - 1.14E+06 - - - 1.2538 - 3.443 0.605 - 497.8 1 2 0 0.0029 19 0 0 0 4.17E+06 2.98E+06 - - - 8.3218 0.9999 221125_WJC_METTL3_EV_vs_WT_F02.23726.23726.2 1.15E-06 13/26 R.YSVQLLTPANLLAK.L "sp|Q9Y265|RUVB1_HUMAN,tr|H7C4G5|H7C4G5_HUMAN" 2 1529.8817 0.67 22409 23726 2 1529.881815 765.9481 RuvB-like 1 OS=Homo sapiens OX=9606 GN=RUVBL1 PE=1 SV=1 8.59 3846.9 - 881807 - - - 0.0556 - 2.469 0.499 - 566.3 1 2 0 0.0001 14 0 0 0 4.68E+06 7.00E+06 - - - 4.9947 0.9999 221125_WJC_METTL3_EV_vs_WT_F02.23728.23728.3 0.000206 Sep-56 R.AVFVDLEPTVIDEVR.T "sp|Q71U36|TBA1A_HUMAN,sp|P68363|TBA1B_HUMAN,sp|Q9BQE3|TBA1C_HUMAN,tr|F8VS66|F8VS66_HUMAN,tr|F8VWV9|F8VWV9_HUMAN,tr|F8VRZ4|F8VRZ4_HUMAN,tr|F8VVB9|F8VVB9_HUMAN,tr|A0A1W2PQM2|A0A1W2PQM2_HUMAN,tr|F5H5D3|F5H5D3_HUMAN,tr|F8VRK0|F8VRK0_HUMAN,tr|F8VQQ4|F8VQQ4_HUMAN,tr|F8VX09|F8VX09_HUMAN" 12 1700.8985 0.61 22411 23728 3 1700.901312 567.9734 Tubulin alpha-1A chain OS=Homo sapiens OX=9606 GN=TUBA1A PE=1 SV=1 3.92 3847.1 - 840601 - - - 1.6521 - 2.294 0.502 - 90 1 2 0 0.0028 15 0 0 0 2.67E+06 4.36E+06 - - - 6.3026 0.9999 221125_WJC_METTL3_EV_vs_WT_F02.23730.23730.2 6.83E-05 15/28 R.TINLYPLTNYTFGTK.E sp|O43809|CPSF5_HUMAN 1 1744.9036 0.76 22413 23730 2 1744.904357 873.4591 Cleavage and polyadenylation specificity factor subunit 5 OS=Homo sapiens OX=9606 GN=NUDT21 PE=1 SV=1 8.17 3847.4 - 730375 - - - 0.4413 - 2.849 0.523 - 603.4 1 2 0 0.0008 15 0 0 0 5.17E+06 6.77E+06 - - - 5.4777 0.9997 221125_WJC_METTL3_EV_vs_WT_F02.23736.23736.2 0.000111 22-Jul R.LFPPQWIC[160.03]C[160.03]DIR[166.11].Y sp|Q86U44|MTA70_HUMAN 1 1613.7722 0.05 22418 23736 2 1613.774939 807.8934 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 5.82 3848.1 - 1.58E+07 - - - 1.6911 - 1.607 0.532 - 119.8 1 2 0 0.0027 12 0 0 0 8.26E+06 1.74E+08 - - - 4.2176 1 221125_WJC_METTL3_EV_vs_WT_F02.23739.23739.3 5.48E-07 14/56 K.GFHQVPFAPIVFIER[166.11].T "sp|P47897|SYQ_HUMAN,tr|B4DDN1|B4DDN1_HUMAN,tr|H7C0R3|H7C0R3_HUMAN,tr|A0A0U1RQX5|A0A0U1RQX5_HUMAN,tr|A0A1B0GVU9|A0A1B0GVU9_HUMAN,tr|A0A0U1RRC8|A0A0U1RRC8_HUMAN" 6 1765.9543 1.35 22421 23739 3 1765.954624 589.6587 Glutamine--tRNA ligase OS=Homo sapiens OX=9606 GN=QARS1 PE=1 SV=1 6.75 3848.4 - 2.17E+06 - - - 0.1659 - 2.392 0.5 - 266.5 1 2 0 0.0003 15 0 0 0 1.71E+07 1.26E+07 - - - 6.3901 0.9999 221125_WJC_METTL3_EV_vs_WT_F02.23740.23740.2 2.55E-05 18-Sep K.FQWDLNAWTK[136.11].S "sp|Q13263|TIF1B_HUMAN,tr|M0R0K9|M0R0K9_HUMAN" 2 1315.6441 0.73 22422 23740 2 1315.643566 658.8293 Transcription intermediary factor 1-beta OS=Homo sapiens OX=9606 GN=TRIM28 PE=1 SV=5 5.84 3848.5 - 2.00E+06 - - - -0.3846 - 1.928 0.529 - 199.9 1 2 0 -0.0005 10 0 0 0 6.49E+06 8.94E+06 - - - 4.7805 0.9998 221125_WJC_METTL3_EV_vs_WT_F02.23741.23741.2 1.15E-09 16/26 K.SVEEVASEIQPFLR.G sp|P15924|DESP_HUMAN 1 1602.8253 999 22423 23741 2 1602.829076 802.4199 Desmoplakin OS=Homo sapiens OX=9606 GN=DSP PE=1 SV=3 4.25 3848.5 - 1.88E+06 - - - 2.3328 - 3.226 0.504 - 887.6 1 2 0 0.0037 14 0 0 0 1.09E+07 0.00E+00 - - - 5.7015 1 221125_WJC_METTL3_EV_vs_WT_F02.23742.23742.3 1.33E-08 17/76 K.VAYTEADYYHTELWMEQALR[166.11].Q sp|P13674|P4HA1_HUMAN 1 2498.1452 1.77 22424 23742 3 2498.145789 833.7223 Prolyl 4-hydroxylase subunit alpha-1 OS=Homo sapiens OX=9606 GN=P4HA1 PE=1 SV=2 4.4 3848.6 - 1.83E+06 - - - 0.2434 - 2.955 0.594 - 323.5 1 2 0 0.0006 20 0 0 0 9.59E+06 5.43E+06 - - - 7.7909 0.9999 221125_WJC_METTL3_EV_vs_WT_F02.23744.23744.2 5.19E-06 18-Sep K.FQWDLNAWTK.S "sp|Q13263|TIF1B_HUMAN,tr|M0R0K9|M0R0K9_HUMAN" 2 1307.6299 0.73 22426 23744 2 1307.630879 654.8222 Transcription intermediary factor 1-beta OS=Homo sapiens OX=9606 GN=TRIM28 PE=1 SV=5 5.84 3848.8 - 1.36E+06 - - - 0.7701 - 1.921 0.539 - 205.2 1 2 0 0.001 10 0 0 0 6.49E+06 8.94E+06 - - - 4.844 1 221125_WJC_METTL3_EV_vs_WT_F02.23745.23745.4 1.17E-08 21/150 R.VYTADPYHALAPAASYGVGAVASLYR.G "sp|O43251|RFOX2_HUMAN,tr|B0QYV1|B0QYV1_HUMAN,tr|A0A0G2JRD1|A0A0G2JRD1_HUMAN,tr|A0A0G2JRA5|A0A0G2JRA5_HUMAN,tr|S4R3K7|S4R3K7_HUMAN" 5 2682.3442 1.14 22427 23745 4 2682.348661 671.5933 RNA binding protein fox-1 homolog 2 OS=Homo sapiens OX=9606 GN=RBFOX2 PE=1 SV=3 6.71 3848.9 - 1.28E+06 - - - 1.6624 - 2.93 0.514 - 233.7 1 2 0 0.0045 26 0 0 0 5.81E+06 5.09E+06 - - - 4.0377 0.9997 221125_WJC_METTL3_EV_vs_WT_F02.23753.23753.2 0.00178 28-Oct R.ALTVPELTQQMFDSK.N "sp|Q9BVA1|TBB2B_HUMAN,sp|Q13885|TBB2A_HUMAN" 2 1706.8549 1.33 22435 23753 2 1706.853216 854.4347 Tubulin beta-2B chain OS=Homo sapiens OX=9606 GN=TUBB2B PE=1 SV=1 4.37 3849.8 - 773992 - - - -1.0001 - 2.124 0.377 - 230.4 1 2 0 -0.0017 15 0 0 0 6.45E+06 4.84E+06 - - - 3.677 0.9996 221125_WJC_METTL3_EV_vs_WT_F02.23755.23755.2 1.95E-06 13/24 R.TGTLVEEAFWIDK.L "sp|Q9UKV3|ACINU_HUMAN,tr|G3V3B0|G3V3B0_HUMAN,tr|S4R3H4|S4R3H4_HUMAN,tr|E7EQT4|E7EQT4_HUMAN" 4 1507.7559 -1 22437 23755 2 1507.751529 754.8852 Apoptotic chromatin condensation inducer in the nucleus OS=Homo sapiens OX=9606 GN=ACIN1 PE=1 SV=2 4.14 3850.1 - 498304 - - - -2.8731 - 2.146 0.562 - 486.1 1 2 0 -0.0043 13 0 0 0 0.00E+00 0.00E+00 - - - 5.1504 1 221125_WJC_METTL3_EV_vs_WT_F02.23757.23757.3 1.36E-17 26/100 R.VYTADPYHALAPAASYGVGAVASLYR.G "sp|O43251|RFOX2_HUMAN,tr|B0QYV1|B0QYV1_HUMAN,tr|A0A0G2JRD1|A0A0G2JRD1_HUMAN,tr|A0A0G2JRA5|A0A0G2JRA5_HUMAN,tr|S4R3K7|S4R3K7_HUMAN" 5 2682.3442 1.36 22438 23757 3 2682.345592 895.122 RNA binding protein fox-1 homolog 2 OS=Homo sapiens OX=9606 GN=RBFOX2 PE=1 SV=3 6.71 3850.3 - 7.41E+06 - - - 0.5182 - 4.713 0.747 - 475.1 1 2 0 0.0014 26 0 0 0 5.06E+07 3.73E+07 - - - 10.4347 1 221125_WJC_METTL3_EV_vs_WT_F02.23758.23758.3 8.63E-09 21/60 R.IPDEIIDMVK[136.11]EEVVAK[136.11].G "sp|Q9Y4Z0|LSM4_HUMAN,tr|U3KQK1|U3KQK1_HUMAN,tr|V9GZ56|V9GZ56_HUMAN" 3 1842.9984 1.81 22439 23758 3 1842.999002 615.3401 U6 snRNA-associated Sm-like protein LSm4 OS=Homo sapiens OX=9606 GN=LSM4 PE=1 SV=1 4.18 3850.4 - 1.89E+06 - - - 0.3521 - 3.643 0.609 - 741 1 2 1 0.0006 16 0 0 0 1.36E+07 7.48E+06 - - - 8.6467 0.9999 221125_WJC_METTL3_EV_vs_WT_F02.23759.23759.3 9.90E-05 22/72 R.ISGVGIDQPPYGIFVINQK.T sp|Q02413|DSG1_HUMAN 1 2044.0993 999 22440 23759 3 2044.108464 682.3737 Desmoglein-1 OS=Homo sapiens OX=9606 GN=DSG1 PE=1 SV=2 5.83 3850.4 - 4.09E+06 - - - 4.4699 - 3.736 0.578 - 719.9 1 2 0 0.0091 19 0 0 0 2.94E+07 0.00E+00 - - - 8.2197 1 221125_WJC_METTL3_EV_vs_WT_F02.23760.23760.3 1.07E-09 17/76 K.VAYTEADYYHTELWMEQALR.Q sp|P13674|P4HA1_HUMAN 1 2488.1369 1.77 22441 23760 3 2488.142784 830.3862 Prolyl 4-hydroxylase subunit alpha-1 OS=Homo sapiens OX=9606 GN=P4HA1 PE=1 SV=2 4.4 3850.5 - 2.64E+06 - - - 2.3604 - 3.544 0.613 - 328.3 1 2 0 0.0059 20 0 0 0 9.59E+06 5.43E+06 - - - 8.4423 0.9627 221125_WJC_METTL3_EV_vs_WT_F02.23761.23761.2 0.000349 14/28 K.VTIAQGGVLPNIQAV.L "sp|Q9BTM1|H2AJ_HUMAN,sp|Q93077|H2A1C_HUMAN,sp|Q99878|H2A1J_HUMAN,sp|Q16777|H2A2C_HUMAN,sp|P04908|H2A1B_HUMAN,sp|P20671|H2A1D_HUMAN,sp|P0C0S8|H2A1_HUMAN,sp|Q6FI13|H2A2A_HUMAN,sp|Q96KK5|H2A1H_HUMAN,sp|Q7L7L0|H2A3_HUMAN,tr|A0A0U1RR32|A0A0U1RR32_HUMAN,tr|A0A0U1RRH7|A0A0U1RRH7_HUMAN,tr|H0YFX9|H0YFX9_HUMAN" 13 1478.8457 - 22442 23761 2 1478.848984 740.4301 Histone H2A.J OS=Homo sapiens OX=9606 GN=H2AJ PE=1 SV=1 5.49 3850.6 - 1.60E+06 - - - 2.2349 - 2.338 0.369 - 466.1 1 1 0 0.0033 15 0 0 0 - - - - - 3.8534 1 221125_WJC_METTL3_EV_vs_WT_F02.23765.23765.3 6.87E-15 22/96 R.TPYTMSYGDSLYYNNAYGALDAYYK.R sp|Q9BWF3|RBM4_HUMAN 1 2903.2636 1.37 22446 23765 3 2903.266107 968.7618 RNA-binding protein 4 OS=Homo sapiens OX=9606 GN=RBM4 PE=1 SV=1 4.21 3851.1 - 890715 - - - 0.8539 - 4.588 0.745 - 514.6 1 2 0 0.0025 25 0 0 0 1.12E+07 8.15E+06 - - - 10.3502 1 221125_WJC_METTL3_EV_vs_WT_F02.23767.23767.2 2.13E-07 17/28 K.VQSDGQIVLVDDWIK[136.11].L sp|Q08211|DHX9_HUMAN 1 1721.908 0.87 22448 23767 2 1721.908822 861.9613 ATP-dependent RNA helicase A OS=Homo sapiens OX=9606 GN=DHX9 PE=1 SV=4 3.93 3851.3 - 787461 - - - 0.5058 - 3.329 0.631 - 1063.8 1 2 0 0.0009 15 0 0 0 3.45E+06 3.98E+06 - - - 6.6581 1 221125_WJC_METTL3_EV_vs_WT_F02.23772.23772.2 4.30E-08 14/32 R.EAFDLFDADGTGTIDVK.E sp|P41208|CETN2_HUMAN 1 1812.8418 3.27 22453 23772 2 1812.843243 907.4282 Centrin-2 OS=Homo sapiens OX=9606 GN=CETN2 PE=1 SV=1 3.71 3852 - 439102 - - - 0.8098 - 2.623 0.614 - 496.1 1 2 0 0.0015 17 0 0 0 2.25E+06 6.88E+05 - - - 5.9464 1 221125_WJC_METTL3_EV_vs_WT_F02.23778.23778.2 2.72E-08 16/34 R.ALLEAFGTTGFQATNFGR[166.11].A "sp|P49366|DHYS_HUMAN,tr|M0QX43|M0QX43_HUMAN,tr|Q5J8M5|Q5J8M5_HUMAN,tr|B4E3M2|B4E3M2_HUMAN,tr|A0A087WZK0|A0A087WZK0_HUMAN,tr|A0A3B3IU31|A0A3B3IU31_HUMAN,tr|M0R253|M0R253_HUMAN" 7 1909.9562 -1 22458 23778 2 1910.95618 955.9854 Deoxyhypusine synthase OS=Homo sapiens OX=9606 GN=DHPS PE=1 SV=1 6.05 3852.7 - 272821 - - - 523.5712 - 3.751 0.636 - 890.5 1 2 0 1 18 0 0 0 0.00E+00 0.00E+00 - - - 6.6747 1 221125_WJC_METTL3_EV_vs_WT_F02.23780.23780.3 1.50E-13 19/96 R.TPYTMSYGDSLYYNNAYGALDAYYK[136.11].R sp|Q9BWF3|RBM4_HUMAN 1 2911.2778 1.37 22459 23780 3 2911.282493 971.4332 RNA-binding protein 4 OS=Homo sapiens OX=9606 GN=RBM4 PE=1 SV=1 4.21 3853 - 1.96E+06 - - - 1.6024 - 3.946 0.716 - 301.4 1 2 0 0.0047 25 0 0 0 1.12E+07 8.15E+06 - - - 9.6795 1 221125_WJC_METTL3_EV_vs_WT_F02.23781.23781.3 1.11E-06 22/88 R.LPPQIFNSPFSLPSEHLAPPPLK.Y "sp|P42694|HELZ_HUMAN,tr|J3QS41|J3QS41_HUMAN" 2 2525.3682 4.42 22460 23781 3 2525.375059 842.7967 Probable helicase with zinc finger domain OS=Homo sapiens OX=9606 GN=HELZ PE=1 SV=2 6.75 3853.1 - 1.10E+06 - - - 2.7034 - 3.391 0.576 - 353.5 1 2 0 0.0068 23 0 0 0 7.36E+06 1.66E+06 - - - 7.8246 0.9999 221125_WJC_METTL3_EV_vs_WT_F02.23782.23782.3 1.97E-05 Oct-44 R.LFPPQWIC[160.03]C[160.03]DIR[166.11].Y sp|Q86U44|MTA70_HUMAN 1 1613.7722 0.01 22461 23782 3 1613.774899 538.9313 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 5.82 3853.1 - 1.74E+06 - - - 1.6663 - 1.929 0.536 - 141.2 1 2 0 0.0027 12 0 0 0 1.45E+05 9.98E+06 - - - 6.3362 1 221125_WJC_METTL3_EV_vs_WT_F02.23785.23785.2 1.65E-17 19/34 R.C[160.03]YC[160.03]ADVIYPMAVVATAER.G "sp|P78406|RAE1L_HUMAN,tr|E9PQ57|E9PQ57_HUMAN,tr|E9PPG9|E9PPG9_HUMAN" 3 2087.9479 2.08 22464 23785 2 2087.951949 1044.9812 mRNA export factor OS=Homo sapiens OX=9606 GN=RAE1 PE=1 SV=1 4.37 3853.4 - 572327 - - - 1.9613 - 3.563 0.771 - 851.5 1 2 0 0.0041 18 0 0 0 1.05E+07 5.08E+06 - - - 7.8582 0.9998 221125_WJC_METTL3_EV_vs_WT_F02.23786.23786.2 3.00E-05 13/28 R.IVEANPLLEAFGNAK.T "sp|Q9UM54|MYO6_HUMAN,tr|A0A590UK86|A0A590UK86_HUMAN,tr|A0A590UK71|A0A590UK71_HUMAN,tr|A0A0D9SGC1|A0A0D9SGC1_HUMAN,tr|A0A0A0MRM8|A0A0A0MRM8_HUMAN,tr|A0A5F9ZI03|A0A5F9ZI03_HUMAN,tr|A0A590UK22|A0A590UK22_HUMAN,tr|A0A590UJY4|A0A590UJY4_HUMAN,tr|A0A590UJ40|A0A590UJ40_HUMAN,tr|A0A590UJ75|A0A590UJ75_HUMAN,tr|E7EW20|E7EW20_HUMAN,tr|A0A590UKB0|A0A590UKB0_HUMAN,tr|A0A1Y0BRN3|A0A1Y0BRN3_HUMAN" 13 1584.8512 2.32 22465 23786 2 1584.85327 793.4329 Unconventional myosin-VI OS=Homo sapiens OX=9606 GN=MYO6 PE=1 SV=4 4.53 3853.6 - 502065 - - - 1.3326 - 2.732 0.48 - 446.3 1 2 0 0.0021 15 0 0 0 4.77E+06 2.05E+06 - - - 5.0565 0.9997 221125_WJC_METTL3_EV_vs_WT_F02.23787.23787.3 2.62E-05 Dec-36 R.WALWFFKNDK.S "sp|P06730|IF4E_HUMAN,tr|H0Y8J7|H0Y8J7_HUMAN,tr|D6RBW1|D6RBW1_HUMAN" 3 1353.687 1.45 22466 23787 3 1353.689126 452.2363 Eukaryotic translation initiation factor 4E OS=Homo sapiens OX=9606 GN=EIF4E PE=1 SV=2 8.59 3853.7 - 496868 - - - 1.5757 - 2.145 0.473 - 177.5 1 2 1 0.0021 10 0 0 0 1.65E+06 1.14E+06 - - - 6.0416 0.9991 221125_WJC_METTL3_EV_vs_WT_F02.23788.23788.2 4.03E-08 28-Dec R.TINLYPLTNYTFGTK[136.11].E sp|O43809|CPSF5_HUMAN 1 1752.9178 0.76 22467 23788 2 1752.924956 877.4662 Cleavage and polyadenylation specificity factor subunit 5 OS=Homo sapiens OX=9606 GN=NUDT21 PE=1 SV=1 8.17 3853.8 - 462157 - - - 4.0898 - 2.404 0.595 - 407.3 1 2 0 0.0072 15 0 0 0 5.17E+06 6.77E+06 - - - 5.5899 0.9979 221125_WJC_METTL3_EV_vs_WT_F02.23789.23789.2 1.18E-05 24-Nov R.LLSFSPEEFPTLK.A sp|Q5JSZ5|PRC2B_HUMAN 1 1506.797 2.88 22468 23789 2 1506.803993 754.4058 Protein PRRC2B OS=Homo sapiens OX=9606 GN=PRRC2B PE=1 SV=2 4.53 3854 - 449739 - - - 4.643 - 2.155 0.492 - 379.8 1 2 0 0.007 13 0 0 0 1.61E+06 5.57E+05 - - - 4.6433 1 221125_WJC_METTL3_EV_vs_WT_F02.23792.23792.2 2.05E-07 15/34 R.ALLEAFGTTGFQATNFGR.A "sp|P49366|DHYS_HUMAN,tr|M0QX43|M0QX43_HUMAN,tr|Q5J8M5|Q5J8M5_HUMAN,tr|B4E3M2|B4E3M2_HUMAN,tr|A0A087WZK0|A0A087WZK0_HUMAN,tr|A0A3B3IU31|A0A3B3IU31_HUMAN,tr|M0R253|M0R253_HUMAN" 7 1899.9479 -1 22471 23792 2 1899.955271 950.9812 Deoxyhypusine synthase OS=Homo sapiens OX=9606 GN=DHPS PE=1 SV=1 6.05 3854.3 - 374872 - - - 3.8733 - 3.154 0.58 - 544 1 2 0 0.0074 18 0 0 0 0.00E+00 0.00E+00 - - - 6.1466 1 221125_WJC_METTL3_EV_vs_WT_F02.23796.23796.2 2.00E-07 15/36 K.GLPLGSAVSSPVLFSPVGR.R sp|Q8WUM0|NU133_HUMAN 1 1839.0254 2.04 22475 23796 2 1839.033091 920.52 Nuclear pore complex protein Nup133 OS=Homo sapiens OX=9606 GN=NUP133 PE=1 SV=2 9.75 3854.9 - 269286 - - - 4.1636 - 3.219 0.588 - 452.4 1 2 0 0.0077 19 0 0 0 1.96E+06 9.58E+05 - - - 6.2558 0.998 221125_WJC_METTL3_EV_vs_WT_F02.23797.23797.2 0.00146 Jun-34 R.ALLEAFGTTGFQATNFGR[166.11].A "sp|P49366|DHYS_HUMAN,tr|M0QX43|M0QX43_HUMAN,tr|Q5J8M5|Q5J8M5_HUMAN,tr|B4E3M2|B4E3M2_HUMAN,tr|A0A087WZK0|A0A087WZK0_HUMAN,tr|A0A3B3IU31|A0A3B3IU31_HUMAN,tr|M0R253|M0R253_HUMAN" 7 1909.9562 -1 22476 23797 2 1909.961039 955.9854 Deoxyhypusine synthase OS=Homo sapiens OX=9606 GN=DHPS PE=1 SV=1 6.05 3855 - 232495 - - - 2.543 - 1.544 0.371 - 99.2 1 2 0 0.0049 18 0 0 0 0.00E+00 0.00E+00 - - - 2.8476 0.9996 221125_WJC_METTL3_EV_vs_WT_F02.23801.23801.2 8.85E-08 16/28 K.VSALDLAVLDQVEAR.L "sp|Q13561|DCTN2_HUMAN,tr|H0YHL1|H0YHL1_HUMAN,tr|A8K8J9|A8K8J9_HUMAN,tr|F8W1I6|F8W1I6_HUMAN,tr|A0A7I2V4H4|A0A7I2V4H4_HUMAN,tr|A0A7I2V4Y9|A0A7I2V4Y9_HUMAN" 6 1597.8675 3.89 22479 23801 2 1597.871585 799.941 Dynactin subunit 2 OS=Homo sapiens OX=9606 GN=DCTN2 PE=1 SV=4 4.03 3855.6 - 377183 - - - 2.534 - 2.992 0.427 - 952.5 1 2 0 0.004 15 0 0 0 6.01E+06 1.54E+06 - - - 4.888 0.9192 221125_WJC_METTL3_EV_vs_WT_F02.23802.23802.2 0.383 22-Apr K.AAASHLFPFEQL.- sp|Q01831|XPC_HUMAN 1 1329.6717 - 22480 23802 2 1329.674288 665.8431 DNA repair protein complementing XP-C cells OS=Homo sapiens OX=9606 GN=XPC PE=1 SV=4 5.24 3855.8 - 198238 - - - 1.9185 - 1.13 0.15 - 28.8 44 2 0 0.0026 12 0 0 0 - - - - - -0.2645 1 221125_WJC_METTL3_EV_vs_WT_F02.23803.23803.2 3.32E-12 22/38 K.MLVDDIGDVTITNDGATILK[136.11].L "sp|P17987|TCPA_HUMAN,tr|F5H726|F5H726_HUMAN,tr|F5H136|F5H136_HUMAN,tr|F5GZI8|F5GZI8_HUMAN,tr|E7ERF2|E7ERF2_HUMAN,tr|F5H676|F5H676_HUMAN" 6 2111.0911 0.46 22481 23803 2 2111.094975 1056.5528 T-complex protein 1 subunit alpha OS=Homo sapiens OX=9606 GN=TCP1 PE=1 SV=1 3.77 3855.9 - 1.78E+06 - - - 1.818 - 4.334 0.704 - 1217.4 1 2 0 0.0038 20 0 0 0 1.07E+07 2.33E+07 - - - 7.845 0.9996 221125_WJC_METTL3_EV_vs_WT_F02.23804.23804.2 3.88E-06 15/24 K.TLNDELEIIEGMK[136.11].F "sp|P10809|CH60_HUMAN,tr|A0A7I2V2X6|A0A7I2V2X6_HUMAN,tr|A0A7I2V599|A0A7I2V599_HUMAN,tr|E7EXB4|E7EXB4_HUMAN,tr|A0A7I2YQ71|A0A7I2YQ71_HUMAN,tr|E7ESH4|E7ESH4_HUMAN,tr|A0A7I2V5M1|A0A7I2V5M1_HUMAN,tr|A0A7I2V5K3|A0A7I2V5K3_HUMAN,tr|A0A7I2V369|A0A7I2V369_HUMAN" 9 1511.7633 1.55 22482 23804 2 1511.767557 756.8889 "60 kDa heat shock protein, mitochondrial OS=Homo sapiens OX=9606 GN=HSPD1 PE=1 SV=2" 4 3856 - 1.50E+06 - - - 2.8417 - 2.661 0.547 - 448 1 2 0 0.0043 13 0 0 0 2.96E+09 1.91E+09 - - - 5.5917 1 221125_WJC_METTL3_EV_vs_WT_F02.23805.23805.2 4.16E-06 16/24 K.TLNDELEIIEGMK.F "sp|P10809|CH60_HUMAN,tr|A0A7I2V2X6|A0A7I2V2X6_HUMAN,tr|A0A7I2V599|A0A7I2V599_HUMAN,tr|E7EXB4|E7EXB4_HUMAN,tr|A0A7I2YQ71|A0A7I2YQ71_HUMAN,tr|E7ESH4|E7ESH4_HUMAN,tr|A0A7I2V5M1|A0A7I2V5M1_HUMAN,tr|A0A7I2V5K3|A0A7I2V5K3_HUMAN,tr|A0A7I2V369|A0A7I2V369_HUMAN" 9 1503.7491 1.55 22483 23805 2 1503.75431 752.8818 "60 kDa heat shock protein, mitochondrial OS=Homo sapiens OX=9606 GN=HSPD1 PE=1 SV=2" 4 3856.1 - 1.48E+06 - - - 3.4906 - 2.75 0.578 - 598.2 1 2 0 0.0052 13 0 0 0 2.97E+09 1.92E+09 - - - 5.9048 0.9999 221125_WJC_METTL3_EV_vs_WT_F02.23806.23806.3 2.36E-09 19/68 R.C[160.03]YC[160.03]ADVIYPMAVVATAER.G "sp|P78406|RAE1L_HUMAN,tr|E9PQ57|E9PQ57_HUMAN,tr|E9PPG9|E9PPG9_HUMAN" 3 2087.9479 1.71 22484 23806 3 2087.957123 696.9899 mRNA export factor OS=Homo sapiens OX=9606 GN=RAE1 PE=1 SV=1 4.37 3856.2 - 1.27E+06 - - - 4.4393 - 3.252 0.625 - 517.4 1 2 0 0.0093 18 0 0 0 1.45E+07 8.50E+06 - - - 8.4421 0.9999 221125_WJC_METTL3_EV_vs_WT_F02.23807.23807.3 2.08E-12 24/76 K.MLVDDIGDVTITNDGATILK.L "sp|P17987|TCPA_HUMAN,tr|F5H726|F5H726_HUMAN,tr|F5H136|F5H136_HUMAN,tr|F5GZI8|F5GZI8_HUMAN,tr|E7ERF2|E7ERF2_HUMAN,tr|F5H676|F5H676_HUMAN" 6 2103.0769 0.46 22485 23807 3 2103.084233 702.0329 T-complex protein 1 subunit alpha OS=Homo sapiens OX=9606 GN=TCP1 PE=1 SV=1 3.77 3856.3 - 1.17E+06 - - - 3.4692 - 4.197 0.573 - 673.5 1 2 0 0.0073 20 0 0 0 1.34E+07 2.89E+07 - - - 8.4062 1 221125_WJC_METTL3_EV_vs_WT_F02.23808.23808.3 2.81E-14 19/84 K.DFMIQGGDFVNGDGTGVASIYR.G "sp|O43447|PPIH_HUMAN,tr|A0A7I2YQS4|A0A7I2YQS4_HUMAN,tr|C9JQD4|C9JQD4_HUMAN" 3 2318.0637 1.38 22486 23808 3 2318.072139 773.6952 Peptidyl-prolyl cis-trans isomerase H OS=Homo sapiens OX=9606 GN=PPIH PE=1 SV=1 3.93 3856.4 - 768633 - - - 3.6207 - 3.212 0.743 - 406.8 1 2 0 0.0084 22 0 0 0 6.01E+06 4.35E+06 - - - 9.5879 0.9927 221125_WJC_METTL3_EV_vs_WT_F02.23811.23811.2 1.45E-06 13/28 R.IVEANPLLEAFGNAK[136.11].T "sp|Q9UM54|MYO6_HUMAN,tr|A0A590UK86|A0A590UK86_HUMAN,tr|A0A590UK71|A0A590UK71_HUMAN,tr|A0A0D9SGC1|A0A0D9SGC1_HUMAN,tr|A0A0A0MRM8|A0A0A0MRM8_HUMAN,tr|A0A5F9ZI03|A0A5F9ZI03_HUMAN,tr|A0A590UK22|A0A590UK22_HUMAN,tr|A0A590UJY4|A0A590UJY4_HUMAN,tr|A0A590UJ40|A0A590UJ40_HUMAN,tr|A0A590UJ75|A0A590UJ75_HUMAN,tr|E7EW20|E7EW20_HUMAN,tr|A0A590UKB0|A0A590UKB0_HUMAN,tr|A0A1Y0BRN3|A0A1Y0BRN3_HUMAN" 13 1592.8654 -1 22489 23811 2 1592.876189 797.44 Unconventional myosin-VI OS=Homo sapiens OX=9606 GN=MYO6 PE=1 SV=4 4.53 3856.8 - 600272 - - - 6.7997 - 2.477 0.496 - 435.8 1 2 0 0.0108 15 0 0 0 0.00E+00 0.00E+00 - - - 4.9311 1 221125_WJC_METTL3_EV_vs_WT_F02.23812.23812.2 1.99E-12 20/38 K.MLVDDIGDVTITNDGATILK.L "sp|P17987|TCPA_HUMAN,tr|F5H726|F5H726_HUMAN,tr|F5H136|F5H136_HUMAN,tr|F5GZI8|F5GZI8_HUMAN,tr|E7ERF2|E7ERF2_HUMAN,tr|F5H676|F5H676_HUMAN" 6 2103.0769 0.46 22490 23812 2 2103.081516 1052.5457 T-complex protein 1 subunit alpha OS=Homo sapiens OX=9606 GN=TCP1 PE=1 SV=1 3.77 3856.9 - 595566 - - - 2.1773 - 3.962 0.702 - 944.7 1 2 0 0.0046 20 0 0 0 1.07E+07 2.33E+07 - - - 7.6093 0.9999 221125_WJC_METTL3_EV_vs_WT_F02.23813.23813.3 2.33E-09 18/76 K.GYFNNNIPPVEFTQENPFC[160.03]R.F sp|Q7Z3B4|NUP54_HUMAN 1 2442.1063 2.79 22491 23813 3 2442.116665 815.0427 Nucleoporin p54 OS=Homo sapiens OX=9606 GN=NUP54 PE=1 SV=2 4.53 3857 - 509521 - - - 4.2525 - 3.216 0.572 - 442 1 2 0 0.0104 20 0 0 0 3.48E+06 1.24E+06 - - - 7.7483 0.9999 221125_WJC_METTL3_EV_vs_WT_F02.23817.23817.3 4.48E-06 20/48 K.TLNDELEIIEGMK.F "sp|P10809|CH60_HUMAN,tr|A0A7I2V2X6|A0A7I2V2X6_HUMAN,tr|A0A7I2V599|A0A7I2V599_HUMAN,tr|E7EXB4|E7EXB4_HUMAN,tr|A0A7I2YQ71|A0A7I2YQ71_HUMAN,tr|E7ESH4|E7ESH4_HUMAN,tr|A0A7I2V5M1|A0A7I2V5M1_HUMAN,tr|A0A7I2V5K3|A0A7I2V5K3_HUMAN,tr|A0A7I2V369|A0A7I2V369_HUMAN" 9 1503.7491 1.43 22495 23817 3 1503.754454 502.257 "60 kDa heat shock protein, mitochondrial OS=Homo sapiens OX=9606 GN=HSPD1 PE=1 SV=2" 4 3857.6 - 306138 - - - 3.5864 - 2.978 0.521 - 811.6 1 2 0 0.0054 13 0 0 0 4.87E+08 3.41E+08 - - - 7.3058 0.9983 221125_WJC_METTL3_EV_vs_WT_F02.23818.23818.3 0.00403 Oct-72 K.GLPLGSAVSSPVLFSPVGR.R sp|Q8WUM0|NU133_HUMAN 1 1839.0254 1.29 22496 23818 3 1839.032495 614.0158 Nuclear pore complex protein Nup133 OS=Homo sapiens OX=9606 GN=NUP133 PE=1 SV=2 9.75 3857.7 - 295981 - - - 3.8395 - 2.382 0.334 - 111.4 1 2 0 0.0071 19 0 0 0 8.64E+05 6.71E+05 - - - 4.3942 1 221125_WJC_METTL3_EV_vs_WT_F02.23820.23820.2 1.89E-09 19/30 K.ITISSLQDLTLYNPER.T sp|Q9NZI8|IF2B1_HUMAN 1 1861.9785 1.88 22498 23820 2 1861.984636 931.9965 Insulin-like growth factor 2 mRNA-binding protein 1 OS=Homo sapiens OX=9606 GN=IGF2BP1 PE=1 SV=2 4.37 3858 - 245761 - - - 3.2723 - 3.528 0.617 - 1468.4 1 2 0 0.0061 16 0 0 0 1.15E+08 6.10E+07 - - - 6.6958 0.9999 221125_WJC_METTL3_EV_vs_WT_F02.23822.23822.3 6.99E-07 Sep-56 R.DNMSIVLVC[160.03]FSNAPK.V "sp|O75688|PPM1B_HUMAN,tr|A0A3B3IS24|A0A3B3IS24_HUMAN,tr|C9JIR6|C9JIR6_HUMAN" 3 1693.8168 2.31 22499 23822 3 1693.822578 565.6129 Protein phosphatase 1B OS=Homo sapiens OX=9606 GN=PPM1B PE=1 SV=1 5.83 3858.2 - 1.21E+06 - - - 3.4331 - 1.961 0.577 - 132.5 1 2 0 0.0058 15 0 0 0 5.34E+06 2.31E+06 - - - 6.7287 1 221125_WJC_METTL3_EV_vs_WT_F02.23824.23824.3 2.46E-06 Oct-56 K.LAATNALLNSLEFTK.A "sp|Q14974|IMB1_HUMAN,tr|J3KTM9|J3KTM9_HUMAN" 2 1604.8774 1.6 22501 23824 3 1604.877885 535.9664 Importin subunit beta-1 OS=Homo sapiens OX=9606 GN=KPNB1 PE=1 SV=2 6 3858.4 - 4.06E+06 - - - 0.319 - 2.432 0.493 - 218.6 1 2 0 0.0005 15 0 0 0 2.02E+07 1.26E+07 - - - 6.3553 1 221125_WJC_METTL3_EV_vs_WT_F02.23825.23825.3 7.91E-12 18/80 Y.LGYPVTNAVITVPAYFNDSQR[166.11].Q "sp|P0DMV8|HS71A_HUMAN,sp|P0DMV9|HS71B_HUMAN,tr|A0A0G2JIW1|A0A0G2JIW1_HUMAN" 3 2334.1884 0.1 22502 23825 3 2334.191089 779.0701 Heat shock 70 kDa protein 1A OS=Homo sapiens OX=9606 GN=HSPA1A PE=1 SV=1 5.83 3858.4 - 2.49E+06 - - - 1.1661 - 3.467 0.654 - 223.9 1 1 0 0.0027 21 0 0 0 1.50E+06 1.57E+07 - - - 8.8114 0.9999 221125_WJC_METTL3_EV_vs_WT_F02.23826.23826.2 0.000279 16/28 R.QILLYSATFPLSVQK[136.11].F sp|P26196|DDX6_HUMAN 1 1714.9749 1.03 22503 23826 2 1714.972317 858.4947 Probable ATP-dependent RNA helicase DDX6 OS=Homo sapiens OX=9606 GN=DDX6 PE=1 SV=2 8.59 3858.5 - 2.35E+06 - - - -1.5108 - 3.241 0.505 - 857.3 1 2 0 -0.0026 15 0 0 0 4.80E+07 4.64E+07 - - - 5.6611 0.9999 221125_WJC_METTL3_EV_vs_WT_F02.23827.23827.2 0.000809 13/28 R.QILLYSATFPLSVQK.F sp|P26196|DDX6_HUMAN 1 1706.9607 1.03 22504 23827 2 1706.961278 854.4876 Probable ATP-dependent RNA helicase DDX6 OS=Homo sapiens OX=9606 GN=DDX6 PE=1 SV=2 8.59 3858.5 - 2.13E+06 - - - 0.3339 - 2.762 0.478 - 469.4 1 2 0 0.0006 15 0 0 0 4.80E+07 4.64E+07 - - - 5.0691 0.9998 221125_WJC_METTL3_EV_vs_WT_F02.23832.23832.3 0.0553 Dec-56 R.QILLYSATFPLSVQK[136.11].F sp|P26196|DDX6_HUMAN 1 1714.9749 1.1 22509 23832 3 1714.973751 572.6656 Probable ATP-dependent RNA helicase DDX6 OS=Homo sapiens OX=9606 GN=DDX6 PE=1 SV=2 8.59 3858.8 - 990258 - - - -0.6746 - 1.959 0.373 - 144.5 1 2 0 -0.0012 15 0 0 0 1.80E+07 1.64E+07 - - - 4.4529 1 221125_WJC_METTL3_EV_vs_WT_F02.23833.23833.2 6.48E-08 14/30 R.LFVGNLPADITEDEFK[136.11].R sp|P23246|SFPQ_HUMAN 1 1814.9182 1.41 22510 23833 2 1814.909677 908.4664 "Splicing factor, proline- and glutamine-rich OS=Homo sapiens OX=9606 GN=SFPQ PE=1 SV=2" 3.92 3858.9 - 931005 - - - -4.6856 - 3.147 0.632 - 435 1 2 0 -0.0085 16 0 0 0 1.26E+07 8.91E+06 - - - 6.5249 0.9998 221125_WJC_METTL3_EV_vs_WT_F02.23834.23834.3 0.00732 Dec-56 R.QILLYSATFPLSVQK.F sp|P26196|DDX6_HUMAN 1 1706.9607 1.1 22511 23834 3 1706.963065 569.9942 Probable ATP-dependent RNA helicase DDX6 OS=Homo sapiens OX=9606 GN=DDX6 PE=1 SV=2 8.59 3859 - 772182 - - - 1.3808 - 2.308 0.364 - 144.4 1 2 0 0.0024 15 0 0 0 1.80E+07 1.64E+07 - - - 4.78 1 221125_WJC_METTL3_EV_vs_WT_F02.23835.23835.2 1.66E-09 16/30 R.LFVGNLPADITEDEFK.R sp|P23246|SFPQ_HUMAN 1 1806.904 1.15 22512 23835 2 1806.89971 904.4593 "Splicing factor, proline- and glutamine-rich OS=Homo sapiens OX=9606 GN=SFPQ PE=1 SV=2" 3.92 3859.1 - 659546 - - - -2.3637 - 3.369 0.64 - 500.8 1 2 0 -0.0043 16 0 0 0 1.31E+07 1.14E+07 - - - 6.7529 0.9999 221125_WJC_METTL3_EV_vs_WT_F02.23837.23837.3 1.58E-05 Oct-52 R.NFTTEQVTAMLLSK[136.11].L "sp|P34932|HSP74_HUMAN,tr|A0A087WTS8|A0A087WTS8_HUMAN,tr|A0A087WYC1|A0A087WYC1_HUMAN" 3 1589.8214 0.04 22514 23837 3 1589.82039 530.9478 Heat shock 70 kDa protein 4 OS=Homo sapiens OX=9606 GN=HSPA4 PE=1 SV=4 6 3859.3 - 419256 - - - -0.663 - 2.08 0.48 - 172.1 1 2 0 -0.0011 14 0 0 0 3.28E+05 8.44E+06 - - - 5.8375 0.9999 221125_WJC_METTL3_EV_vs_WT_F02.23838.23838.2 2.07E-05 18-Sep R.DLTSWVTEMK.A "sp|Q13813|SPTN1_HUMAN,tr|A0A0D9SF54|A0A0D9SF54_HUMAN,tr|A0A0D9SGF6|A0A0D9SGF6_HUMAN" 3 1208.5747 1.15 22515 23838 2 1208.57392 605.2946 "Spectrin alpha chain, non-erythrocytic 1 OS=Homo sapiens OX=9606 GN=SPTAN1 PE=1 SV=3" 4.37 3859.4 - 389308 - - - -0.6661 - 1.89 0.52 - 218.1 1 2 0 -0.0008 10 0 0 0 7.04E+06 6.10E+06 - - - 4.6583 0.9999 221125_WJC_METTL3_EV_vs_WT_F02.23842.23842.3 6.96E-05 Nov-48 K.TLNDELEIIEGMK[136.11].F "sp|P10809|CH60_HUMAN,tr|A0A7I2V2X6|A0A7I2V2X6_HUMAN,tr|A0A7I2V599|A0A7I2V599_HUMAN,tr|E7EXB4|E7EXB4_HUMAN,tr|A0A7I2YQ71|A0A7I2YQ71_HUMAN,tr|E7ESH4|E7ESH4_HUMAN,tr|A0A7I2V5M1|A0A7I2V5M1_HUMAN,tr|A0A7I2V5K3|A0A7I2V5K3_HUMAN,tr|A0A7I2V369|A0A7I2V369_HUMAN" 9 1511.7633 1.43 22517 23842 3 1511.761853 504.9284 "60 kDa heat shock protein, mitochondrial OS=Homo sapiens OX=9606 GN=HSPD1 PE=1 SV=2" 4 3859.9 - 1.64E+07 - - - -0.9314 - 2.256 0.462 - 245.8 1 2 0 -0.0014 13 0 0 0 4.87E+08 3.41E+08 - - - 5.8963 1 221125_WJC_METTL3_EV_vs_WT_F02.23843.23843.3 6.11E-07 Nov-60 K.ITISSLQDLTLYNPER.T sp|Q9NZI8|IF2B1_HUMAN 1 1861.9785 1.37 22518 23843 3 1861.977681 621.6668 Insulin-like growth factor 2 mRNA-binding protein 1 OS=Homo sapiens OX=9606 GN=IGF2BP1 PE=1 SV=2 4.37 3860 - 3.48E+06 - - - -0.4629 - 2.268 0.516 - 136.8 1 2 0 -0.0009 16 0 0 0 5.30E+07 3.88E+07 - - - 6.3938 0.9999 221125_WJC_METTL3_EV_vs_WT_F02.23845.23845.2 2.43E-06 24-Dec R.EDGMVPFVFVGTK.E "sp|P51114|FXR1_HUMAN,tr|E7EU85|E7EU85_HUMAN,tr|E9PFF5|E9PFF5_HUMAN,tr|B4DXZ6|B4DXZ6_HUMAN" 4 1424.701 0.76 22520 23845 2 1424.701285 713.3578 Fragile X mental retardation syndrome-related protein 1 OS=Homo sapiens OX=9606 GN=FXR1 PE=1 SV=3 4.37 3860.1 - 3.00E+06 - - - 0.2085 - 2.107 0.574 - 469.2 1 2 0 0.0003 13 0 0 0 2.82E+07 3.71E+07 - - - 5.1932 0.9999 221125_WJC_METTL3_EV_vs_WT_F02.23847.23847.2 2.55E-07 26-Oct R.NFTTEQVTAMLLSK[136.11].L "sp|P34932|HSP74_HUMAN,tr|A0A087WTS8|A0A087WTS8_HUMAN,tr|A0A087WYC1|A0A087WYC1_HUMAN" 3 1589.8214 0.06 22522 23847 2 1589.820663 795.918 Heat shock 70 kDa protein 4 OS=Homo sapiens OX=9606 GN=HSPA4 PE=1 SV=4 6 3860.2 - 2.06E+06 - - - -0.4913 - 2.534 0.555 - 255.4 1 2 0 -0.0008 14 0 0 0 2.03E+06 3.51E+07 - - - 5.4733 1 221125_WJC_METTL3_EV_vs_WT_F02.23848.23848.2 4.50E-08 13/22 R.AQFEGIVTDLIR[166.11].R "sp|P38646|GRP75_HUMAN,tr|H0Y8K0|H0Y8K0_HUMAN,tr|A0A7I2V2S7|A0A7I2V2S7_HUMAN,tr|A0A7I2V2G2|A0A7I2V2G2_HUMAN,tr|A0A7I2V3F7|A0A7I2V3F7_HUMAN,tr|A0A7I2YQB2|A0A7I2YQB2_HUMAN,tr|D6RCD7|D6RCD7_HUMAN" 7 1370.7433 0.49 22523 23848 2 1370.743851 686.3789 "Stress-70 protein, mitochondrial OS=Homo sapiens OX=9606 GN=HSPA9 PE=1 SV=2" 4.37 3860.3 - 1.38E+06 - - - 0.3764 - 2.472 0.586 - 678.2 1 2 0 0.0005 12 0 0 0 2.33E+08 4.76E+08 - - - 5.7503 1 221125_WJC_METTL3_EV_vs_WT_F02.23849.23849.3 1.29E-17 25/100 Y.IMAPGLLHAYPPQVYGYDDLQMLQTR.F "sp|Q14157|UBP2L_HUMAN,tr|F8W726|F8W726_HUMAN,tr|H7C2T8|H7C2T8_HUMAN,tr|H0Y5H6|H0Y5H6_HUMAN" 4 2989.483 1.97 22524 23849 3 2989.483644 997.5016 Ubiquitin-associated protein 2-like OS=Homo sapiens OX=9606 GN=UBAP2L PE=1 SV=2 5.21 3860.4 - 854039 - - - 0.2084 - 4.59 0.739 - 667.3 1 1 0 0.0006 26 0 0 0 1.42E+07 7.22E+06 - - - 10.2848 0.9999 221125_WJC_METTL3_EV_vs_WT_F02.23851.23851.2 3.65E-05 18-Nov R.DLTSWVTEMK[136.11].A "sp|Q13813|SPTN1_HUMAN,tr|A0A0D9SF54|A0A0D9SF54_HUMAN,tr|A0A0D9SGF6|A0A0D9SGF6_HUMAN" 3 1216.5889 1.12 22526 23851 2 1216.588926 609.3017 "Spectrin alpha chain, non-erythrocytic 1 OS=Homo sapiens OX=9606 GN=SPTAN1 PE=1 SV=3" 4.37 3860.6 - 749232 - - - 0.0008 - 2.128 0.472 - 350.2 1 2 0 0 10 0 0 0 7.25E+06 6.46E+06 - - - 4.6351 1 221125_WJC_METTL3_EV_vs_WT_F02.23852.23852.2 1.93E-06 17/30 R.QLNYTIGEVPISFVDR.V "sp|O60762|DPM1_HUMAN,tr|A0A804HJ93|A0A804HJ93_HUMAN,tr|H0Y368|H0Y368_HUMAN,tr|Q5QPK2|Q5QPK2_HUMAN" 4 1849.9574 0.05 22527 23852 2 1849.957405 925.986 Dolichol-phosphate mannosyltransferase subunit 1 OS=Homo sapiens OX=9606 GN=DPM1 PE=1 SV=1 4.37 3860.8 - 437045 - - - -0.0049 - 3.15 0.581 - 839.8 1 2 0 0 16 0 0 0 3.58E+06 7.46E+07 - - - 6.1532 1 221125_WJC_METTL3_EV_vs_WT_F02.23856.23856.2 4.35E-11 20/28 K.LAATNALLNSLEFTK.A "sp|Q14974|IMB1_HUMAN,tr|J3KTM9|J3KTM9_HUMAN" 2 1604.8774 1.95 22529 23856 2 1604.876751 803.446 Importin subunit beta-1 OS=Homo sapiens OX=9606 GN=KPNB1 PE=1 SV=2 6 3861.3 - 2.69E+07 - - - -0.3876 - 3.927 0.602 - 1571 1 2 0 -0.0006 15 0 0 0 8.47E+07 4.34E+07 - - - 6.8502 1 221125_WJC_METTL3_EV_vs_WT_F02.23858.23858.2 7.02E-09 20/30 K.ITISSLQDLTLYNPER[166.11].T sp|Q9NZI8|IF2B1_HUMAN 1 1871.9868 1.88 22530 23858 2 1871.976336 937.0007 Insulin-like growth factor 2 mRNA-binding protein 1 OS=Homo sapiens OX=9606 GN=IGF2BP1 PE=1 SV=2 4.37 3861.5 - 3.53E+06 - - - -5.5967 - 3.619 0.646 - 1768.5 1 2 0 -0.0105 16 0 0 0 1.15E+08 6.10E+07 - - - 6.9712 1 221125_WJC_METTL3_EV_vs_WT_F02.23859.23859.2 7.93E-08 13/22 R.AQFEGIVTDLIR.R "sp|P38646|GRP75_HUMAN,tr|H0Y8K0|H0Y8K0_HUMAN,tr|A0A7I2V2S7|A0A7I2V2S7_HUMAN,tr|A0A7I2V2G2|A0A7I2V2G2_HUMAN,tr|A0A7I2V3F7|A0A7I2V3F7_HUMAN,tr|A0A7I2YQB2|A0A7I2YQB2_HUMAN,tr|D6RCD7|D6RCD7_HUMAN" 7 1360.7351 0.49 22531 23859 2 1360.730168 681.3748 "Stress-70 protein, mitochondrial OS=Homo sapiens OX=9606 GN=HSPA9 PE=1 SV=2" 4.37 3861.6 - 1.86E+06 - - - -3.5988 - 2.528 0.582 - 687.1 1 2 0 -0.0049 12 0 0 0 2.33E+08 4.76E+08 - - - 5.7783 1 221125_WJC_METTL3_EV_vs_WT_F02.23860.23860.3 0.000203 14/60 K.ITISSLQDLTLYNPER[166.11].T sp|Q9NZI8|IF2B1_HUMAN 1 1871.9868 1.37 22532 23860 3 1871.987717 625.0029 Insulin-like growth factor 2 mRNA-binding protein 1 OS=Homo sapiens OX=9606 GN=IGF2BP1 PE=1 SV=2 4.37 3861.6 - 3.07E+06 - - - 0.4829 - 2.632 0.498 - 217.7 1 2 0 0.0009 16 0 0 0 5.30E+07 3.88E+07 - - - 6.5751 0.7832 221125_WJC_METTL3_EV_vs_WT_F02.23862.23862.2 0.001 17/28 K.VSQEILELLNTTTAK[136.11].E "sp|Q86U44|MTA70_HUMAN,tr|H0YFV6|H0YFV6_HUMAN" 2 1666.9233 0.001 22534 23862 2 1667.917123 834.4689 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 4.53 3861.8 - 687897 - - - 596.2218 - 2.601 0.394 - 919.9 1 2 0 0.9939 15 0 0 0 0.00E+00 6.40E+06 - - - 3.9891 0.9994 221125_WJC_METTL3_EV_vs_WT_F02.23863.23863.3 0.0656 14/52 K.LR[166.11]PLYDIPYMFEAR[166.11].E sp|Q7KZF4|SND1_HUMAN 1 1802.9293 0.41 22535 23863 3 1802.92566 601.9837 Staphylococcal nuclease domain-containing protein 1 OS=Homo sapiens OX=9606 GN=SND1 PE=1 SV=1 6.07 3862 - 653359 - - - -1.9923 - 2.284 0.309 - 249.9 1 2 0 -0.0036 14 0 0 0 2.75E+06 6.64E+06 - - - 4.179 0.9997 221125_WJC_METTL3_EV_vs_WT_F02.23864.23864.3 0.203 13/44 R.AQFEGIVTDLIR[166.11].R "sp|P38646|GRP75_HUMAN,tr|H0Y8K0|H0Y8K0_HUMAN,tr|A0A7I2V2S7|A0A7I2V2S7_HUMAN,tr|A0A7I2V2G2|A0A7I2V2G2_HUMAN,tr|A0A7I2V3F7|A0A7I2V3F7_HUMAN,tr|A0A7I2YQB2|A0A7I2YQB2_HUMAN,tr|D6RCD7|D6RCD7_HUMAN" 7 1370.7433 0.43 22536 23864 3 1370.740399 457.9217 "Stress-70 protein, mitochondrial OS=Homo sapiens OX=9606 GN=HSPA9 PE=1 SV=2" 4.37 3862.1 - 644852 - - - -2.1419 - 2.184 0.358 - 296.2 1 2 0 -0.0029 12 0 0 0 2.22E+07 5.17E+07 - - - 4.6958 1 221125_WJC_METTL3_EV_vs_WT_F02.23865.23865.3 6.39E-17 26/100 Y.IMAPGLLHAYPPQVYGYDDLQMLQTR[166.11].F "sp|Q14157|UBP2L_HUMAN,tr|F8W726|F8W726_HUMAN,tr|H7C2T8|H7C2T8_HUMAN,tr|H0Y5H6|H0Y5H6_HUMAN" 4 2999.4913 1.97 22537 23865 3 2999.491568 1000.8377 Ubiquitin-associated protein 2-like OS=Homo sapiens OX=9606 GN=UBAP2L PE=1 SV=2 5.21 3862.2 - 628980 - - - 0.0923 - 4.615 0.725 - 789.1 1 1 0 0.0003 26 0 0 0 1.42E+07 7.22E+06 - - - 10.1413 0.9432 221125_WJC_METTL3_EV_vs_WT_F02.23866.23866.2 0.000548 26-Nov R.GGPPFAFVEFEDPR.D "sp|Q07955|SRSF1_HUMAN,tr|J3QQV5|J3QQV5_HUMAN,tr|J3KTL2|J3KTL2_HUMAN,tr|J3KSW7|J3KSW7_HUMAN" 4 1563.7358 1.25 22538 23866 2 1564.734308 782.8752 Serine\arginine-rich splicing factor 1 OS=Homo sapiens OX=9606 GN=SRSF1 PE=1 SV=2 4.14 3862.4 - 584615 - - - 638.5439 - 1.757 0.462 - 209.3 1 2 0 0.9985 14 0 0 0 4.47E+06 3.57E+06 - - - 3.5541 1 221125_WJC_METTL3_EV_vs_WT_F02.23867.23867.2 5.63E-14 17/36 R.LVSQDNFGFDLPAVEAATK.K "sp|Q01082|SPTB2_HUMAN,tr|A0A087WUZ3|A0A087WUZ3_HUMAN,tr|F8W6C1|F8W6C1_HUMAN" 3 2021.0106 1.93 22539 23867 2 2021.002745 1011.5126 "Spectrin beta chain, non-erythrocytic 1 OS=Homo sapiens OX=9606 GN=SPTBN1 PE=1 SV=2" 4.03 3862.5 - 452491 - - - -3.8728 - 3.531 0.726 - 698.4 1 2 0 -0.0078 19 0 0 0 4.40E+06 2.28E+06 - - - 7.5024 0.9999 221125_WJC_METTL3_EV_vs_WT_F02.23869.23869.2 2.76E-07 28-Nov K.QPEDDLGFDPFDVTR[166.11].K sp|O95628|CNOT4_HUMAN 1 1759.7929 3.95 22541 23869 2 1759.793145 880.9037 CCR4-NOT transcription complex subunit 4 OS=Homo sapiens OX=9606 GN=CNOT4 PE=1 SV=3 3.71 3862.7 - 293853 - - - 0.1591 - 2.082 0.58 - 252.3 1 2 0 0.0003 15 0 0 0 2.64E+07 6.69E+06 - - - 5.1277 1 221125_WJC_METTL3_EV_vs_WT_F02.23876.23876.3 8.63E-10 18/76 K.NAISLPQLNQAAYDSLVVGK.L sp|Q00587|BORG5_HUMAN 1 2100.1215 1.9 22547 23876 3 2100.121982 701.0478 Cdc42 effector protein 1 OS=Homo sapiens OX=9606 GN=CDC42EP1 PE=1 SV=1 5.83 3863.6 - 3.71E+06 - - - 0.2205 - 3.714 0.471 - 444.8 1 2 0 0.0005 20 0 0 0 1.74E+07 9.16E+06 - - - 6.9743 0.9997 221125_WJC_METTL3_EV_vs_WT_F02.23877.23877.2 0.168 14/24 R.GTIEILSDVQLIK.T "sp|Q8NHW5|RLA0L_HUMAN,sp|P05388|RLA0_HUMAN,tr|F8VU65|F8VU65_HUMAN,tr|F8VW21|F8VW21_HUMAN,tr|F8VPE8|F8VPE8_HUMAN" 5 1427.8235 1.09 22548 23877 2 1427.820771 714.919 60S acidic ribosomal protein P0-like OS=Homo sapiens OX=9606 GN=RPLP0P6 PE=5 SV=1 4.37 3863.6 - 1.74E+07 - - - -1.9435 - 2.607 0.421 - 834.1 1 2 0 -0.0028 13 0 0 0 4.73E+07 4.35E+07 - - - 4.6089 0.9997 221125_WJC_METTL3_EV_vs_WT_F02.23878.23878.2 0.00731 13/24 R.GTIEILSDVQLIK[136.11].T "sp|Q8NHW5|RLA0L_HUMAN,sp|P05388|RLA0_HUMAN,tr|F8VU65|F8VU65_HUMAN,tr|F8VW21|F8VW21_HUMAN,tr|F8VPE8|F8VPE8_HUMAN" 5 1435.8377 1.09 22549 23878 2 1435.835543 718.9261 60S acidic ribosomal protein P0-like OS=Homo sapiens OX=9606 GN=RPLP0P6 PE=5 SV=1 4.37 3863.6 - 1.51E+07 - - - -1.5343 - 2.612 0.384 - 619.5 1 2 0 -0.0022 13 0 0 0 4.73E+07 4.35E+07 - - - 4.3407 0.8646 221125_WJC_METTL3_EV_vs_WT_F02.23879.23879.2 0.0108 28-Jul K.QPEDDLGFDPFDVTR.K sp|O95628|CNOT4_HUMAN 1 1749.7846 2.63 22550 23879 2 1749.771847 875.8996 CCR4-NOT transcription complex subunit 4 OS=Homo sapiens OX=9606 GN=CNOT4 PE=1 SV=3 3.71 3863.7 - 5.81E+06 - - - -7.2855 - 1.117 0.352 - 63.6 1 2 0 -0.0127 15 0 0 0 1.66E+07 6.30E+06 - - - 1.9089 0.9992 221125_WJC_METTL3_EV_vs_WT_F02.23881.23881.3 0.059 Nov-44 R.AQFEGIVTDLIR.R "sp|P38646|GRP75_HUMAN,tr|H0Y8K0|H0Y8K0_HUMAN,tr|A0A7I2V2S7|A0A7I2V2S7_HUMAN,tr|A0A7I2V2G2|A0A7I2V2G2_HUMAN,tr|A0A7I2V3F7|A0A7I2V3F7_HUMAN,tr|A0A7I2YQB2|A0A7I2YQB2_HUMAN,tr|D6RCD7|D6RCD7_HUMAN" 7 1360.7351 0.43 22552 23881 3 1360.730783 454.5856 "Stress-70 protein, mitochondrial OS=Homo sapiens OX=9606 GN=HSPA9 PE=1 SV=2" 4.37 3863.8 - 4.60E+06 - - - -3.1468 - 2.251 0.347 - 219.2 1 2 0 -0.0043 12 0 0 0 2.22E+07 5.17E+07 - - - 4.6565 0.9999 221125_WJC_METTL3_EV_vs_WT_F02.23886.23886.3 1.61E-06 16/68 K.VAHNILSGASWVSWGLVK[136.11].G sp|Q8N0X7|SPART_HUMAN 1 1931.0509 0.99 22557 23886 3 1931.045053 644.6909 Spartin OS=Homo sapiens OX=9606 GN=SPART PE=1 SV=1 8.73 3864.4 - 2.30E+06 - - - -3.0108 - 2.668 0.472 - 245.8 1 2 0 -0.0058 18 0 0 0 1.23E+07 1.24E+07 - - - 6.2443 0.9999 221125_WJC_METTL3_EV_vs_WT_F02.23887.23887.2 9.03E-08 15/28 R.ALTVPELTQQMFDAK[136.11].N "sp|P04350|TBB4A_HUMAN,sp|Q13509|TBB3_HUMAN,sp|P68371|TBB4B_HUMAN,tr|A0A0B4J269|A0A0B4J269_HUMAN" 4 1698.8742 1.06 22558 23887 2 1698.872537 850.4444 Tubulin beta-4A chain OS=Homo sapiens OX=9606 GN=TUBB4A PE=1 SV=2 4.37 3864.5 - 2.09E+06 - - - -0.9836 - 2.51 0.557 - 524.4 1 2 0 -0.0017 15 0 0 0 2.74E+07 2.60E+07 - - - 5.417 0.9997 221125_WJC_METTL3_EV_vs_WT_F02.23888.23888.3 0.00476 Nov-48 R.GTIEILSDVQLIK[136.11].T "sp|Q8NHW5|RLA0L_HUMAN,sp|P05388|RLA0_HUMAN,tr|F8VU65|F8VU65_HUMAN,tr|F8VW21|F8VW21_HUMAN,tr|F8VPE8|F8VPE8_HUMAN" 5 1435.8377 1.53 22559 23888 3 1435.833979 479.6199 60S acidic ribosomal protein P0-like OS=Homo sapiens OX=9606 GN=RPLP0P6 PE=5 SV=1 4.37 3864.6 - 1.72E+06 - - - -2.6236 - 2.338 0.384 - 216.7 1 2 0 -0.0038 13 0 0 0 4.56E+06 2.98E+06 - - - 5.1229 0.9999 221125_WJC_METTL3_EV_vs_WT_F02.23889.23889.3 0.000103 13/48 R.GTIEILSDVQLIK.T "sp|Q8NHW5|RLA0L_HUMAN,sp|P05388|RLA0_HUMAN,tr|F8VU65|F8VU65_HUMAN,tr|F8VW21|F8VW21_HUMAN,tr|F8VPE8|F8VPE8_HUMAN" 5 1427.8235 1.53 22560 23889 3 1427.821087 476.9485 60S acidic ribosomal protein P0-like OS=Homo sapiens OX=9606 GN=RPLP0P6 PE=5 SV=1 4.37 3864.7 - 1.70E+06 - - - -1.7222 - 2.169 0.418 - 188.9 1 2 0 -0.0025 13 0 0 0 4.56E+06 2.98E+06 - - - 5.2989 0.9986 221125_WJC_METTL3_EV_vs_WT_F02.23890.23890.2 1.68E-06 28-Dec R.ALTVPELTQQMFDAK.N "sp|P04350|TBB4A_HUMAN,sp|Q13509|TBB3_HUMAN,sp|P68371|TBB4B_HUMAN,tr|A0A0B4J269|A0A0B4J269_HUMAN" 4 1690.86 1.06 22561 23890 2 1690.852558 846.4373 Tubulin beta-4A chain OS=Homo sapiens OX=9606 GN=TUBB4A PE=1 SV=2 4.37 3864.8 - 1.64E+06 - - - -4.406 - 2.208 0.545 - 314.5 1 2 0 -0.0075 15 0 0 0 2.76E+07 2.60E+07 - - - 5.0114 0.999 221125_WJC_METTL3_EV_vs_WT_F02.23896.23896.3 0.0374 Aug-40 R.VTLILELLQHK[136.11].K "sp|Q9H583|HEAT1_HUMAN,tr|Q5T3Q7|Q5T3Q7_HUMAN" 2 1313.8162 -1 22566 23896 3 1313.811548 438.946 HEAT repeat-containing protein 1 OS=Homo sapiens OX=9606 GN=HEATR1 PE=1 SV=3 6.72 3865.6 - 63472.2 - - - -3.5583 - 1.63 0.425 - 119.9 1 2 0 -0.0047 11 0 0 0 0.00E+00 0.00E+00 - - - 4.665 0.9999 221125_WJC_METTL3_EV_vs_WT_F02.23900.23900.3 4.97E-05 Nov-48 R.DITLFHAMDTLYR.H "sp|Q9BTC8|MTA3_HUMAN,tr|E9PCS8|E9PCS8_HUMAN,tr|E7EQY4|E7EQY4_HUMAN,tr|E7EV10|E7EV10_HUMAN,tr|F6RRE2|F6RRE2_HUMAN" 5 1594.7814 1.3 22570 23900 3 1594.778785 532.6011 Metastasis-associated protein MTA3 OS=Homo sapiens OX=9606 GN=MTA3 PE=1 SV=2 5.21 3866.1 - 576746 - - - -1.6171 - 2.002 0.441 - 101.6 1 2 0 -0.0026 13 0 0 0 3.71E+06 2.86E+06 - - - 5.338 0.9995 221125_WJC_METTL3_EV_vs_WT_F02.23901.23901.3 0.00282 Oct-44 R.DVEDEILWVGER.M "sp|Q01082|SPTB2_HUMAN,tr|A0A087WUZ3|A0A087WUZ3_HUMAN" 2 1458.6991 1.45 22571 23901 3 1458.697439 487.2403 "Spectrin beta chain, non-erythrocytic 1 OS=Homo sapiens OX=9606 GN=SPTBN1 PE=1 SV=2" 3.83 3866.2 - 412376 - - - -1.1209 - 1.799 0.336 - 195.8 1 2 0 -0.0016 12 0 0 0 2.87E+06 1.98E+06 - - - 3.9133 0.9998 221125_WJC_METTL3_EV_vs_WT_F02.23902.23902.2 1.43E-05 13/30 K.QFAEENGLLFLEASAK[136.11].T "sp|P61106|RAB14_HUMAN,tr|X6RFL8|X6RFL8_HUMAN" 2 1773.9029 0.99 22572 23902 2 1773.900013 887.9587 Ras-related protein Rab-14 OS=Homo sapiens OX=9606 GN=RAB14 PE=1 SV=4 4.25 3866.3 - 328118 - - - -1.6083 - 2.596 0.524 - 442.8 1 2 0 -0.0029 16 0 0 0 8.47E+06 8.57E+06 - - - 5.2558 0.9998 221125_WJC_METTL3_EV_vs_WT_F02.23904.23904.2 9.82E-07 26-Dec K.STVFGTALNYVSLR.L "sp|P48449|LSS_HUMAN,tr|C9J315|C9J315_HUMAN" 2 1526.8093 2.88 22574 23904 2 1526.810312 764.4119 Lanosterol synthase OS=Homo sapiens OX=9606 GN=LSS PE=1 SV=1 8.46 3866.6 - 270054 - - - 0.6674 - 2.323 0.408 - 438.5 1 2 0 0.001 14 0 0 0 3.26E+06 1.13E+06 - - - 4.1693 0.9735 221125_WJC_METTL3_EV_vs_WT_F02.23905.23905.2 0.0697 26-Aug K.LYTLVTYVPVTTFK.N "sp|P62899|RL31_HUMAN,tr|B7Z4C8|B7Z4C8_HUMAN,tr|B7Z4E3|B7Z4E3_HUMAN,tr|H7C2W9|H7C2W9_HUMAN,tr|C9JU56|C9JU56_HUMAN" 5 1643.9174 -1 22575 23905 2 1643.910709 822.966 60S ribosomal protein L31 OS=Homo sapiens OX=9606 GN=RPL31 PE=1 SV=1 8.5 3866.7 - 188820 - - - -4.0987 - 1.44 0.217 - 147.8 1 2 0 -0.0067 14 0 0 0 0.00E+00 0.00E+00 - - - 1.5567 1 221125_WJC_METTL3_EV_vs_WT_F02.23907.23907.2 3.64E-09 14/38 K.NAISLPQLNQAAYDSLVVGK[136.11].L sp|Q00587|BORG5_HUMAN 1 2108.1357 1.52 22577 23907 2 2108.133776 1055.0751 Cdc42 effector protein 1 OS=Homo sapiens OX=9606 GN=CDC42EP1 PE=1 SV=1 5.83 3867 - 0 - - - -0.9217 - 3.037 0.569 - 424.6 1 2 0 -0.0019 20 0 0 0 3.59E+06 2.37E+06 - - - 5.9741 0.9925 221125_WJC_METTL3_EV_vs_WT_F02.23912.23912.3 9.77E-10 31/120 R.FGGFGGPGGVGGLGGPGGFGPGGYPGGIHEV.S sp|P35908|K22E_HUMAN 1 2670.2615 - 22580 23912 3 2670.270957 891.0945 "Keratin, type II cytoskeletal 2 epidermal OS=Homo sapiens OX=9606 GN=KRT2 PE=1 SV=2" 5.24 3867.6 - 1.21E+06 - - - 3.5285 - 3.678 0.563 - 429.6 1 1 0 0.0094 31 0 0 0 - - - - - 7.8106 0.9999 221125_WJC_METTL3_EV_vs_WT_F02.23915.23915.3 2.08E-08 Dec-68 R.AYPDVAALSDGYWVVSNR.V "sp|O14773|TPP1_HUMAN,tr|A0A804HJ17|A0A804HJ17_HUMAN,tr|A0A2R8YGD1|A0A2R8YGD1_HUMAN,tr|A0A2R8Y7U1|A0A2R8Y7U1_HUMAN,tr|A0A2R8YD45|A0A2R8YD45_HUMAN" 5 1981.9534 12.51 22583 23915 3 1981.958716 661.6584 Tripeptidyl-peptidase 1 OS=Homo sapiens OX=9606 GN=TPP1 PE=1 SV=2 4.21 3868 - 566260 - - - 2.6867 - 2.359 0.563 - 158.7 1 2 0 0.0053 18 0 0 0 5.00E+06 4.00E+05 - - - 6.9525 0.9992 221125_WJC_METTL3_EV_vs_WT_F02.23917.23917.2 2.41E-06 18-Oct K.LLEPVLLLGK.E "sp|P62249|RS16_HUMAN,tr|M0R210|M0R210_HUMAN,tr|M0R3H0|M0R3H0_HUMAN,tr|M0QX76|M0QX76_HUMAN,tr|M0R1M5|M0R1M5_HUMAN,tr|Q6IPX4|Q6IPX4_HUMAN" 6 1093.7111 0.9 22585 23917 2 1093.711281 547.8628 40S ribosomal protein S16 OS=Homo sapiens OX=9606 GN=RPS16 PE=1 SV=2 6 3868.3 - 387780 - - - 0.181 - 2.018 0.222 - 202.7 1 2 0 0.0002 10 0 0 0 3.52E+06 3.91E+06 - - - 2.6404 0.9985 221125_WJC_METTL3_EV_vs_WT_F02.23920.23920.2 2.46E-07 26-Oct K.VWDLAQQVVLSSYR.A "sp|Q9BQA1|MEP50_HUMAN,tr|H0Y711|H0Y711_HUMAN" 2 1662.873 2.94 22588 23920 2 1662.880675 832.4438 Methylosome protein 50 OS=Homo sapiens OX=9606 GN=WDR77 PE=1 SV=1 5.81 3868.7 - 281630 - - - 4.642 - 2.542 0.535 - 386.4 1 2 0 0.0077 14 0 0 0 3.00E+06 1.02E+06 - - - 5.3313 0.9999 221125_WJC_METTL3_EV_vs_WT_F02.23925.23925.2 0.000869 13/26 R.SAGLAFSLYQAMAK.D "sp|P50454|SERPH_HUMAN,tr|E9PNX1|E9PNX1_HUMAN,tr|E9PIG2|E9PIG2_HUMAN,tr|E9PPV6|E9PPV6_HUMAN,tr|E9PR70|E9PR70_HUMAN,tr|E9PMI5|E9PMI5_HUMAN,tr|E9PLA6|E9PLA6_HUMAN,tr|E9PRS3|E9PRS3_HUMAN,tr|E9PJH8|E9PJH8_HUMAN,tr|E9PK86|E9PK86_HUMAN" 10 1456.7384 1.77 22591 23925 2 1456.739501 729.3765 Serpin H1 OS=Homo sapiens OX=9606 GN=SERPINH1 PE=1 SV=2 8.31 3869.3 - 3.18E+06 - - - 0.7311 - 2.626 0.503 - 550.1 1 2 0 0.0011 14 0 0 0 3.87E+07 2.19E+07 - - - 5.1786 0.9999 221125_WJC_METTL3_EV_vs_WT_F02.23926.23926.2 8.04E-07 26-Oct R.SAGLAFSLYQAMAK[136.11].D "sp|P50454|SERPH_HUMAN,tr|E9PNX1|E9PNX1_HUMAN,tr|E9PIG2|E9PIG2_HUMAN,tr|E9PPV6|E9PPV6_HUMAN,tr|E9PR70|E9PR70_HUMAN,tr|E9PMI5|E9PMI5_HUMAN,tr|E9PLA6|E9PLA6_HUMAN,tr|E9PRS3|E9PRS3_HUMAN,tr|E9PJH8|E9PJH8_HUMAN,tr|E9PK86|E9PK86_HUMAN" 10 1464.7526 1.77 22592 23926 2 1464.754158 733.3836 Serpin H1 OS=Homo sapiens OX=9606 GN=SERPINH1 PE=1 SV=2 8.31 3869.4 - 1.60E+06 - - - 1.0391 - 2.37 0.534 - 274.9 1 2 0 0.0015 14 0 0 0 3.87E+07 2.19E+07 - - - 5.15 0.999 221125_WJC_METTL3_EV_vs_WT_F02.23929.23929.2 2.57E-05 Aug-34 R.AYPDVAALSDGYWVVSNR.V "sp|O14773|TPP1_HUMAN,tr|A0A804HJ17|A0A804HJ17_HUMAN,tr|A0A2R8YGD1|A0A2R8YGD1_HUMAN,tr|A0A2R8Y7U1|A0A2R8Y7U1_HUMAN,tr|A0A2R8YD45|A0A2R8YD45_HUMAN" 5 1981.9534 999 22595 23929 2 1981.960024 991.984 Tripeptidyl-peptidase 1 OS=Homo sapiens OX=9606 GN=TPP1 PE=1 SV=2 4.21 3869.8 - 0 - - - 3.3467 - 1.748 0.528 - 143.9 1 2 0 0.0066 18 0 0 0 1.42E+06 0.00E+00 - - - 4.3118 1 221125_WJC_METTL3_EV_vs_WT_F02.23931.23931.3 1.77E-09 16/56 R.ALTVPELTQQMFDAK.N "sp|P04350|TBB4A_HUMAN,sp|Q13509|TBB3_HUMAN,sp|P68371|TBB4B_HUMAN,tr|A0A0B4J269|A0A0B4J269_HUMAN" 4 1690.86 0.82 22596 23931 3 1690.859586 564.6273 Tubulin beta-4A chain OS=Homo sapiens OX=9606 GN=TUBB4A PE=1 SV=2 4.37 3870 - 1.10E+06 - - - -0.2496 - 2.853 0.553 - 318.3 1 2 0 -0.0004 15 0 0 0 1.17E+07 1.43E+07 - - - 7.4409 1 221125_WJC_METTL3_EV_vs_WT_F02.23933.23933.3 7.69E-07 15/72 R.SPFEGAVTESQSLFSDNFR.H sp|O95628|CNOT4_HUMAN 1 2116.9702 2.35 22597 23933 3 2116.974278 706.664 CCR4-NOT transcription complex subunit 4 OS=Homo sapiens OX=9606 GN=CNOT4 PE=1 SV=3 4.14 3870.2 - 568959 - - - 1.9433 - 2.741 0.535 - 242 1 2 0 0.0041 19 0 0 0 6.66E+06 2.84E+06 - - - 6.9808 1 221125_WJC_METTL3_EV_vs_WT_F02.23934.23934.3 2.59E-05 16/56 K.ITPENLPQILLQLK[136.11]R[166.11].R "sp|P43243|MATR3_HUMAN,tr|A8MXP9|A8MXP9_HUMAN,tr|D6R991|D6R991_HUMAN,tr|A0A0R4J2E8|A0A0R4J2E8_HUMAN,tr|D6REM6|D6REM6_HUMAN" 5 1793.0894 1.12 22598 23934 3 1793.093271 598.7037 Matrin-3 OS=Homo sapiens OX=9606 GN=MATR3 PE=1 SV=2 8.75 3870.4 - 946592 - - - 2.1728 - 3.054 0.573 - 364.5 1 2 0 0.0039 15 0 0 0 1.51E+07 1.34E+07 - - - 7.8405 0.9999 221125_WJC_METTL3_EV_vs_WT_F02.23936.23936.3 0.000907 14/56 K.ITPENLPQILLQLKR.R "sp|P43243|MATR3_HUMAN,tr|A8MXP9|A8MXP9_HUMAN,tr|D6R991|D6R991_HUMAN,tr|A0A0R4J2E8|A0A0R4J2E8_HUMAN,tr|D6REM6|D6REM6_HUMAN" 5 1775.0669 1.12 22600 23936 3 1775.070812 592.6962 Matrin-3 OS=Homo sapiens OX=9606 GN=MATR3 PE=1 SV=2 8.75 3870.6 - 1.07E+06 - - - 2.201 - 2.443 0.484 - 287.2 1 2 0 0.0039 15 0 0 0 1.51E+07 1.34E+07 - - - 6.2658 0.9909 221125_WJC_METTL3_EV_vs_WT_F02.23938.23938.3 0.0139 13/60 R.VLQGLEIELQSQLSMK.A "sp|P08779|K1C16_HUMAN,tr|K7ENW6|K7ENW6_HUMAN" 2 1814.9812 8.14 22602 23938 3 1814.993479 606.001 "Keratin, type I cytoskeletal 16 OS=Homo sapiens OX=9606 GN=KRT16 PE=1 SV=4" 4.53 3870.8 - 749314 - - - 6.7731 - 2.49 0.34 - 194.9 1 2 0 0.0123 16 0 0 0 1.63E+07 2.00E+06 - - - 4.6681 1 221125_WJC_METTL3_EV_vs_WT_F02.23939.23939.3 8.34E-11 16/64 R.NTVVLFVPQQEAWVVER.M sp|Q9UJZ1|STML2_HUMAN 1 2013.0684 1.97 22603 23939 3 2013.07281 672.0301 "Stomatin-like protein 2, mitochondrial OS=Homo sapiens OX=9606 GN=STOML2 PE=1 SV=1" 4.53 3871 - 714833 - - - 2.2101 - 3.241 0.599 - 483 1 2 0 0.0044 17 0 0 0 9.42E+06 4.79E+06 - - - 8.1877 1 221125_WJC_METTL3_EV_vs_WT_F02.23940.23940.3 1.63E-05 15/56 K.GAEILEVLHSLPAVR.Q "sp|Q15008|PSMD6_HUMAN,tr|H7C531|H7C531_HUMAN" 2 1602.9093 0.68 22604 23940 3 1602.911036 535.3104 26S proteasome non-ATPase regulatory subunit 6 OS=Homo sapiens OX=9606 GN=PSMD6 PE=1 SV=1 5.4 3871.1 - 708178 - - - 1.0568 - 2.99 0.465 - 372.6 1 2 0 0.0017 15 0 0 0 2.52E+06 3.73E+06 - - - 6.5818 1 221125_WJC_METTL3_EV_vs_WT_F02.23942.23942.2 3.60E-09 Dec-34 R.GGESIYGGFFEDESFAVK[136.11].H "sp|Q13427|PPIG_HUMAN,tr|A0A7I2V629|A0A7I2V629_HUMAN,tr|C9JM79|C9JM79_HUMAN,tr|C9JN15|C9JN15_HUMAN,tr|A0A7I2V4F2|A0A7I2V4F2_HUMAN,tr|A0A7I2V5Q5|A0A7I2V5Q5_HUMAN,tr|A0A7I2V4W3|A0A7I2V4W3_HUMAN" 7 1945.8825 1.32 22606 23942 2 1945.879949 973.9485 Peptidyl-prolyl cis-trans isomerase G OS=Homo sapiens OX=9606 GN=PPIG PE=1 SV=2 4 3871.3 - 498271 - - - -1.3233 - 2.595 0.646 - 363.6 1 2 0 -0.0026 18 0 0 0 4.03E+06 3.05E+06 - - - 6.156 1 221125_WJC_METTL3_EV_vs_WT_F02.23946.23946.2 2.87E-06 19/32 R.NTVVLFVPQQEAWVVER[166.11].M sp|Q9UJZ1|STML2_HUMAN 1 2023.0766 1.37 22610 23946 2 2023.08227 1012.5456 "Stomatin-like protein 2, mitochondrial OS=Homo sapiens OX=9606 GN=STOML2 PE=1 SV=1" 4.53 3871.9 - 370589 - - - 2.7873 - 3.697 0.609 - 739.7 1 2 0 0.0056 17 0 0 0 7.53E+06 5.50E+06 - - - 6.7519 0.9994 221125_WJC_METTL3_EV_vs_WT_F02.23947.23947.2 0.000226 24-Aug K.NGEDLGVAFWISK[136.11].D "sp|Q1KMD3|HNRL2_HUMAN,tr|H3BQZ7|H3BQZ7_HUMAN" 2 1442.7285 3.12 22611 23947 2 1442.731355 722.3715 Heterogeneous nuclear ribonucleoprotein U-like protein 2 OS=Homo sapiens OX=9606 GN=HNRNPUL2 PE=1 SV=1 4.37 3872 - 333673 - - - 1.9581 - 1.819 0.418 - 121.9 1 2 0 0.0028 13 0 0 0 1.86E+07 5.94E+06 - - - 3.663 1 221125_WJC_METTL3_EV_vs_WT_F02.23948.23948.2 3.92E-05 17/32 R.NTVVLFVPQQEAWVVER.M sp|Q9UJZ1|STML2_HUMAN 1 2013.0684 1.37 22612 23948 2 2013.078371 1007.5415 "Stomatin-like protein 2, mitochondrial OS=Homo sapiens OX=9606 GN=STOML2 PE=1 SV=1" 4.53 3872.1 - 307789 - - - 4.9725 - 3.424 0.544 - 569.6 1 2 0 0.01 17 0 0 0 7.53E+06 5.50E+06 - - - 6.0818 0.9999 221125_WJC_METTL3_EV_vs_WT_F02.23950.23950.3 0.000286 Nov-52 R.SAGLAFSLYQAMAK[136.11].D "sp|P50454|SERPH_HUMAN,tr|E9PNX1|E9PNX1_HUMAN,tr|E9PIG2|E9PIG2_HUMAN,tr|E9PPV6|E9PPV6_HUMAN,tr|E9PR70|E9PR70_HUMAN,tr|E9PMI5|E9PMI5_HUMAN,tr|E9PLA6|E9PLA6_HUMAN,tr|E9PRS3|E9PRS3_HUMAN,tr|E9PJH8|E9PJH8_HUMAN,tr|E9PK86|E9PK86_HUMAN" 10 1464.7526 1.57 22614 23950 3 1464.752988 489.2582 Serpin H1 OS=Homo sapiens OX=9606 GN=SERPINH1 PE=1 SV=2 8.31 3872.4 - 219585 - - - 0.2403 - 2.014 0.405 - 127.8 1 2 0 0.0004 14 0 0 0 2.87E+06 1.82E+06 - - - 4.9159 1 221125_WJC_METTL3_EV_vs_WT_F02.23954.23954.2 2.99E-09 14/28 R.ASFETLPNISDLC[160.03]LR.D "sp|Q9H019|MFR1L_HUMAN,tr|E9PRK5|E9PRK5_HUMAN,tr|E9PSD6|E9PSD6_HUMAN,tr|E9PRW1|E9PRW1_HUMAN,tr|C9JF50|C9JF50_HUMAN,tr|E9PLU1|E9PLU1_HUMAN" 6 1734.8611 4.78 22617 23954 2 1734.858969 868.4378 Mitochondrial fission regulator 1-like OS=Homo sapiens OX=9606 GN=MTFR1L PE=1 SV=2 4.37 3873 - 842317 - - - -1.2116 - 2.879 0.593 - 311.8 1 2 0 -0.0021 15 0 0 0 7.62E+06 1.59E+06 - - - 6.02 1 221125_WJC_METTL3_EV_vs_WT_F02.23958.23958.3 1.35E-08 17/64 R.NTVVLFVPQQEAWVVER[166.11].M sp|Q9UJZ1|STML2_HUMAN 1 2023.0766 1.97 22621 23958 3 2023.081569 675.3662 "Stomatin-like protein 2, mitochondrial OS=Homo sapiens OX=9606 GN=STOML2 PE=1 SV=1" 4.53 3873.3 - 1.65E+06 - - - 2.4408 - 3.428 0.598 - 577.1 1 2 0 0.0049 17 0 0 0 9.42E+06 4.79E+06 - - - 8.3181 0.9996 221125_WJC_METTL3_EV_vs_WT_F02.23959.23959.3 3.29E-06 14/60 K.LVTSLPSWALLTNHFK.S "sp|Q9Y467|SALL2_HUMAN,tr|F5H433|F5H433_HUMAN,tr|E7EW59|E7EW59_HUMAN,tr|H0YFS7|H0YFS7_HUMAN" 4 1826.0091 1.06 22622 23959 3 1826.017412 609.677 Sal-like protein 2 OS=Homo sapiens OX=9606 GN=SALL2 PE=1 SV=4 8.76 3873.3 - 1.46E+06 - - - 4.5761 - 2.626 0.477 - 186.3 1 2 0 0.0084 16 0 0 0 3.79E+06 3.58E+06 - - - 6.333 1 221125_WJC_METTL3_EV_vs_WT_F02.23961.23961.3 0.0049 15/60 K.LVTSLPSWALLTNHFK[136.11].S "sp|Q9Y467|SALL2_HUMAN,tr|F5H433|F5H433_HUMAN,tr|E7EW59|E7EW59_HUMAN,tr|H0YFS7|H0YFS7_HUMAN" 4 1834.0233 1.06 22624 23961 3 1834.024308 612.3484 Sal-like protein 2 OS=Homo sapiens OX=9606 GN=SALL2 PE=1 SV=4 8.76 3873.5 - 1.05E+06 - - - 0.5736 - 2.736 0.439 - 227.9 1 2 0 0.0011 16 0 0 0 3.79E+06 3.58E+06 - - - 6.0167 0.9998 221125_WJC_METTL3_EV_vs_WT_F02.23962.23962.3 0.000337 Nov-64 K.NLPLGWDGK[136.11]PIPYWLYK[136.11].L sp|Q12874|SF3A3_HUMAN 1 2075.1215 2.74 22625 23962 3 2075.121908 692.7144 Splicing factor 3A subunit 3 OS=Homo sapiens OX=9606 GN=SF3A3 PE=1 SV=1 8.43 3873.6 - 820646 - - - 0.187 - 2.152 0.378 - 92.4 1 2 0 0.0004 17 0 0 0 1.39E+07 5.07E+06 - - - 4.6904 1 221125_WJC_METTL3_EV_vs_WT_F02.23964.23964.2 7.09E-13 15/34 R.GGESIYGGFFEDESFAVK.H "sp|Q13427|PPIG_HUMAN,tr|A0A7I2V629|A0A7I2V629_HUMAN,tr|C9JM79|C9JM79_HUMAN,tr|C9JN15|C9JN15_HUMAN,tr|A0A7I2V4F2|A0A7I2V4F2_HUMAN,tr|A0A7I2V5Q5|A0A7I2V5Q5_HUMAN,tr|A0A7I2V4W3|A0A7I2V4W3_HUMAN" 7 1937.8683 1.32 22627 23964 2 1937.868583 969.9414 Peptidyl-prolyl cis-trans isomerase G OS=Homo sapiens OX=9606 GN=PPIG PE=1 SV=2 4 3873.9 - 650717 - - - 0.1337 - 3.12 0.682 - 750.3 1 2 0 0.0003 18 0 0 0 4.03E+06 3.05E+06 - - - 6.8756 0.9656 221125_WJC_METTL3_EV_vs_WT_F02.23965.23965.2 4.25E-07 26-Nov L.GENVTIESVADYFK[136.11].Q "sp|P35637|FUS_HUMAN,tr|H3BPE7|H3BPE7_HUMAN" 2 1578.7657 1.97 22628 23965 2 1578.770481 790.3901 RNA-binding protein FUS OS=Homo sapiens OX=9606 GN=FUS PE=1 SV=1 4.14 3874 - 553504 - - - 3.0264 - 2.243 0.502 - 332.9 1 1 0 0.0048 14 0 0 0 6.16E+06 3.13E+06 - - - 4.7744 0.9689 221125_WJC_METTL3_EV_vs_WT_F02.23966.23966.3 0.409 Dec-72 R.QLTVQMMQNPQILAALQER.L "sp|P55209|NP1L1_HUMAN,tr|F8VUX1|F8VUX1_HUMAN,tr|F8W0J6|F8W0J6_HUMAN,tr|F8VXI6|F8VXI6_HUMAN,tr|H0YIV4|H0YIV4_HUMAN,tr|F5H4R6|F5H4R6_HUMAN,tr|F8W020|F8W020_HUMAN,tr|F8VVB5|F8VVB5_HUMAN,tr|F8VY35|F8VY35_HUMAN" 9 2211.1504 -1 22629 23966 3 2211.159276 738.0574 Nucleosome assembly protein 1-like 1 OS=Homo sapiens OX=9606 GN=NAP1L1 PE=1 SV=1 6 3874.1 - 484313 - - - 4.0174 - 1.709 0.227 - 126.7 1 2 0 0.0089 19 0 0 0 0.00E+00 0.00E+00 - - - 2.385 1 221125_WJC_METTL3_EV_vs_WT_F02.23967.23967.3 1.56E-06 Dec-52 R.SAGLAFSLYQAMAK.D "sp|P50454|SERPH_HUMAN,tr|E9PNX1|E9PNX1_HUMAN,tr|E9PIG2|E9PIG2_HUMAN,tr|E9PPV6|E9PPV6_HUMAN,tr|E9PR70|E9PR70_HUMAN,tr|E9PMI5|E9PMI5_HUMAN,tr|E9PLA6|E9PLA6_HUMAN,tr|E9PRS3|E9PRS3_HUMAN,tr|E9PJH8|E9PJH8_HUMAN,tr|E9PK86|E9PK86_HUMAN" 10 1456.7384 1.57 22630 23967 3 1456.740549 486.5868 Serpin H1 OS=Homo sapiens OX=9606 GN=SERPINH1 PE=1 SV=2 8.31 3874.3 - 411867 - - - 1.4505 - 2.482 0.554 - 178.8 1 2 0 0.0021 14 0 0 0 2.87E+06 1.82E+06 - - - 7.1318 1 221125_WJC_METTL3_EV_vs_WT_F02.23978.23978.3 6.93E-15 32/120 K.AFLADPSAFVAAAPVAAATTAAPAAAAAPAK.V "sp|P05388|RLA0_HUMAN,tr|F8VWS0|F8VWS0_HUMAN,tr|F8W1K8|F8W1K8_HUMAN" 3 2751.4596 1.35 22639 23978 3 2751.467511 918.1605 60S acidic ribosomal protein P0 OS=Homo sapiens OX=9606 GN=RPLP0 PE=1 SV=1 5.88 3875.6 - 1.54E+06 - - - 2.8876 - 5.578 0.671 - 958 1 2 0 0.0079 31 0 0 0 1.37E+07 1.01E+07 - - - 9.9732 0.9554 221125_WJC_METTL3_EV_vs_WT_F02.23980.23980.2 0.479 Jul-36 R.GPSPEGYLVGNQQAWLALR[166.11].Q sp|Q17RM4|CC142_HUMAN 1 2065.062 1.6 22641 23980 2 2065.055972 1033.5383 Coiled-coil domain-containing protein 142 OS=Homo sapiens OX=9606 GN=CCDC142 PE=2 SV=1 6 3875.8 - 1.31E+06 - - - -2.9403 - 1.312 0.135 - 78.9 2 2 0 -0.0061 19 0 0 0 8.37E+06 5.24E+06 - - - 0.5694 0.9669 221125_WJC_METTL3_EV_vs_WT_F02.23986.23986.2 0.000254 20-Dec Q.FILDDFIQNDR[166.11].A sp|Q08211|DHX9_HUMAN 1 1404.6913 0.7 22647 23986 2 1404.695202 703.3529 ATP-dependent RNA helicase A OS=Homo sapiens OX=9606 GN=DHX9 PE=1 SV=4 3.93 3876.5 - 584343 - - - 2.7778 - 2.249 0.449 - 415.7 1 1 0 0.0039 11 0 0 0 3.76E+06 5.39E+06 - - - 4.5486 0.9872 221125_WJC_METTL3_EV_vs_WT_F02.23988.23988.2 0.000603 20-Dec Q.FILDDFIQNDR.A sp|Q08211|DHX9_HUMAN 1 1394.683 0.73 22649 23988 2 1394.6837 698.3488 ATP-dependent RNA helicase A OS=Homo sapiens OX=9606 GN=DHX9 PE=1 SV=4 3.93 3876.8 - 511380 - - - 0.4804 - 2.188 0.396 - 443.4 1 1 0 0.0007 11 0 0 0 3.76E+06 5.18E+06 - - - 4.0838 1 221125_WJC_METTL3_EV_vs_WT_F02.23990.23990.3 2.08E-06 13/48 K.DSPLLLQQISAMR.L "sp|Q14203|DCTN1_HUMAN,tr|A0A804CDA6|A0A804CDA6_HUMAN,tr|E7EX90|E7EX90_HUMAN,tr|A0A7P0Z4C3|A0A7P0Z4C3_HUMAN,tr|E7EWF7|E7EWF7_HUMAN" 5 1470.7864 1.76 22651 23990 3 1470.788246 491.2694 Dynactin subunit 1 OS=Homo sapiens OX=9606 GN=DCTN1 PE=1 SV=3 5.84 3877.1 - 207131 - - - 1.2218 - 2.891 0.588 - 273.2 1 2 0 0.0018 13 0 0 0 4.09E+06 2.32E+06 - - - 7.9734 0.9999 221125_WJC_METTL3_EV_vs_WT_F02.23995.23995.2 6.55E-06 26-Dec R.IDFYFDENPYFENK[136.11].V "sp|Q01105|SET_HUMAN,sp|P0DME0|SETLP_HUMAN,tr|A0A0C4DFV9|A0A0C4DFV9_HUMAN" 3 1847.8134 1.01 22655 23995 2 1847.814256 924.914 Protein SET OS=Homo sapiens OX=9606 GN=SET PE=1 SV=3 3.92 3877.7 - 1.02E+06 - - - 0.473 - 2.584 0.562 - 573.9 1 2 0 0.0009 14 0 0 0 5.16E+06 5.13E+06 - - - 5.574 0.9601 221125_WJC_METTL3_EV_vs_WT_F02.23996.23996.2 0.00662 28-Oct R.ASFETLPNISDLC[160.03]LR[166.11].D "sp|Q9H019|MFR1L_HUMAN,tr|E9PRK5|E9PRK5_HUMAN,tr|E9PSD6|E9PSD6_HUMAN,tr|E9PRW1|E9PRW1_HUMAN,tr|C9JF50|C9JF50_HUMAN,tr|E9PLU1|E9PLU1_HUMAN" 6 1744.8693 4.78 22656 23996 2 1745.873484 873.4419 Mitochondrial fission regulator 1-like OS=Homo sapiens OX=9606 GN=MTFR1L PE=1 SV=2 4.37 3877.8 - 554038 - - - 575.4832 - 1.808 0.304 - 177.6 1 2 0 1.0041 15 0 0 0 7.62E+06 1.59E+06 - - - 2.427 1 221125_WJC_METTL3_EV_vs_WT_F02.23997.23997.2 9.33E-05 16/24 K.DSPLLLQQISAMR.L "sp|Q14203|DCTN1_HUMAN,tr|A0A804CDA6|A0A804CDA6_HUMAN,tr|E7EX90|E7EX90_HUMAN,tr|A0A7P0Z4C3|A0A7P0Z4C3_HUMAN,tr|E7EWF7|E7EWF7_HUMAN" 5 1470.7864 1.9 22657 23997 2 1470.787688 736.4005 Dynactin subunit 1 OS=Homo sapiens OX=9606 GN=DCTN1 PE=1 SV=3 5.84 3877.9 - 6.96E+06 - - - 0.8424 - 3.127 0.551 - 1070.8 1 2 0 0.0012 13 0 0 0 4.75E+07 2.50E+07 - - - 6.0363 1 221125_WJC_METTL3_EV_vs_WT_F02.23998.23998.2 2.68E-09 16/24 K.DSPLLLQQISAMR[166.11].L "sp|Q14203|DCTN1_HUMAN,tr|A0A804CDA6|A0A804CDA6_HUMAN,tr|E7EX90|E7EX90_HUMAN,tr|A0A7P0Z4C3|A0A7P0Z4C3_HUMAN,tr|E7EWF7|E7EWF7_HUMAN" 5 1480.7947 1.9 22658 23998 2 1480.796798 741.4046 Dynactin subunit 1 OS=Homo sapiens OX=9606 GN=DCTN1 PE=1 SV=3 5.84 3877.9 - 4.08E+06 - - - 1.404 - 2.951 0.591 - 988.9 1 2 0 0.0021 13 0 0 0 4.75E+07 2.50E+07 - - - 6.1828 0.9999 221125_WJC_METTL3_EV_vs_WT_F02.24010.24010.2 0.000145 14/28 K.EIELIGSGGFGQVFK.A "sp|P19525|E2AK2_HUMAN,tr|A0A7P0TAL9|A0A7P0TAL9_HUMAN,tr|A0A7P0Z4M0|A0A7P0Z4M0_HUMAN,tr|A0A7P0TBA9|A0A7P0TBA9_HUMAN" 4 1579.8246 -1 22670 24010 2 1579.824386 790.9196 "Interferon-induced, double-stranded RNA-activated protein kinase OS=Homo sapiens OX=9606 GN=EIF2AK2 PE=1 SV=2" 4.53 3879.3 - 598165 - - - -0.1412 - 2.877 0.432 - 624.9 1 2 0 -0.0002 15 0 0 0 0.00E+00 0.00E+00 - - - 4.8297 1 221125_WJC_METTL3_EV_vs_WT_F02.24011.24011.3 7.17E-08 Nov-60 R.YEDAYQYQNIFGPLVK.L sp|Q92900|RENT1_HUMAN 1 1946.9414 0.81 22671 24011 3 1946.945088 649.9878 Regulator of nonsense transcripts 1 OS=Homo sapiens OX=9606 GN=UPF1 PE=1 SV=2 4.37 3879.4 - 556200 - - - 1.8788 - 2.545 0.588 - 81.1 1 2 0 0.0037 16 0 0 0 5.70E+06 7.02E+06 - - - 7.4915 0.9999 221125_WJC_METTL3_EV_vs_WT_F02.24013.24013.3 9.30E-05 Sep-52 K.SSANVEEAFFTLAR.D "sp|Q92930|RAB8B_HUMAN,tr|H0YNE9|H0YNE9_HUMAN" 2 1540.7522 -1 22673 24013 3 1540.753028 514.5913 Ras-related protein Rab-8B OS=Homo sapiens OX=9606 GN=RAB8B PE=1 SV=2 4.53 3879.7 - 336509 - - - 0.5556 - 1.506 0.494 - 60 1 2 0 0.0009 14 0 0 0 0.00E+00 0.00E+00 - - - 5.1355 1 221125_WJC_METTL3_EV_vs_WT_F02.24014.24014.2 6.30E-11 14/30 R.YEDAYQYQNIFGPLVK[136.11].L sp|Q92900|RENT1_HUMAN 1 1954.9556 0.99 22674 24014 2 1954.955531 978.4851 Regulator of nonsense transcripts 1 OS=Homo sapiens OX=9606 GN=UPF1 PE=1 SV=2 4.37 3879.8 - 318087 - - - -0.0506 - 2.823 0.74 - 501.6 1 2 0 -0.0001 16 0 0 0 4.15E+06 4.18E+06 - - - 7.0581 0.9999 221125_WJC_METTL3_EV_vs_WT_F02.24017.24017.3 0.000137 Nov-56 R.LHLFPDEYIPEDILK[136.11].N "sp|Q9BYD1|RM13_HUMAN,tr|E5RJI7|E5RJI7_HUMAN" 2 1848.9753 2.67 22676 24017 3 1848.977567 617.3324 "39S ribosomal protein L13, mitochondrial OS=Homo sapiens OX=9606 GN=MRPL13 PE=1 SV=1" 4.31 3880.1 - 352549 - - - 1.225 - 2.25 0.409 - 138.1 1 2 0 0.0023 15 0 0 0 3.09E+06 1.16E+06 - - - 5.2153 0.9997 221125_WJC_METTL3_EV_vs_WT_F02.24021.24021.2 2.88E-05 22-Aug R.LFPPQWIC[160.03]C[160.03]DIR[166.11].Y sp|Q86U44|MTA70_HUMAN 1 1613.7722 0.001 22680 24021 2 1613.774658 807.8934 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 5.82 3880.3 - 3.68E+06 - - - 1.5169 - 1.758 0.543 - 147.6 1 2 0 0.0024 12 0 0 0 0.00E+00 1.09E+08 - - - 4.5353 1 221125_WJC_METTL3_EV_vs_WT_F02.24024.24024.2 1.30E-12 17/30 R.SAFSNLFGGEPLSYTR.F "sp|P02786|TFR1_HUMAN,tr|F8WBE5|F8WBE5_HUMAN" 2 1744.842 1.48 22683 24024 2 1744.844996 873.4283 Transferrin receptor protein 1 OS=Homo sapiens OX=9606 GN=TFRC PE=1 SV=2 5.72 3880.6 - 1.31E+06 - - - 1.6884 - 3.614 0.672 - 845.1 1 2 0 0.0029 16 0 0 0 8.35E+06 5.66E+06 - - - 7.1622 1 221125_WJC_METTL3_EV_vs_WT_F02.24029.24029.3 1.82E-11 20/88 R.LPQGSLVPYMPNAVEQASEAVYK.L "sp|Q8NFF5|FAD1_HUMAN,tr|Q5T191|Q5T191_HUMAN,tr|Q5T196|Q5T196_HUMAN" 3 2490.2465 0.86 22688 24029 3 2490.251017 831.0894 FAD synthase OS=Homo sapiens OX=9606 GN=FLAD1 PE=1 SV=1 4.53 3881.2 - 734237 - - - 1.8291 - 3.481 0.683 - 400.7 1 2 0 0.0046 23 0 0 0 2.00E+06 2.32E+06 - - - 9.0797 0.9996 221125_WJC_METTL3_EV_vs_WT_F02.24031.24031.2 1.16E-05 28-Dec R.ELNSSPQPYLVPFLK[136.11].R "sp|O00268|TAF4_HUMAN,tr|A0A0G2JRY5|A0A0G2JRY5_HUMAN" 2 1738.9385 1.07 22690 24031 2 1738.941632 870.4765 Transcription initiation factor TFIID subunit 4 OS=Homo sapiens OX=9606 GN=TAF4 PE=1 SV=2 6.1 3881.5 - 709334 - - - 1.7879 - 2.076 0.454 - 306.4 1 2 0 0.0031 15 0 0 0 5.33E+06 4.99E+06 - - - 4.1891 0.9999 221125_WJC_METTL3_EV_vs_WT_F02.24034.24034.3 2.64E-06 13/56 R.LHLFPDEYIPEDILK.N "sp|Q9BYD1|RM13_HUMAN,tr|E5RJI7|E5RJI7_HUMAN" 2 1840.9611 1.67 22693 24034 3 1840.96551 614.661 "39S ribosomal protein L13, mitochondrial OS=Homo sapiens OX=9606 GN=MRPL13 PE=1 SV=1" 4.31 3881.9 - 605388 - - - 2.3944 - 2.346 0.478 - 241.7 1 2 0 0.0044 15 0 0 0 1.94E+06 1.16E+06 - - - 6.093 0.9682 221125_WJC_METTL3_EV_vs_WT_F02.24038.24038.3 0.098 Sep-60 R.SAFSNLFGGEPLSYTR.F "sp|P02786|TFR1_HUMAN,tr|F8WBE5|F8WBE5_HUMAN" 2 1744.842 1.03 22696 24038 3 1744.844644 582.6213 Transferrin receptor protein 1 OS=Homo sapiens OX=9606 GN=TFRC PE=1 SV=2 5.72 3882.4 - 855286 - - - 1.4867 - 1.268 0.195 - 36.4 1 2 0 0.0026 16 0 0 0 1.32E+06 1.28E+06 - - - 1.3226 1 221125_WJC_METTL3_EV_vs_WT_F02.24039.24039.2 2.48E-08 14/26 R.GFAFVYFENVDDAK.E "sp|P62995|TRA2B_HUMAN,tr|H7BXF3|H7BXF3_HUMAN" 2 1620.746 1.62 22697 24039 2 1620.746984 811.3803 Transformer-2 protein homolog beta OS=Homo sapiens OX=9606 GN=TRA2B PE=1 SV=1 4.03 3882.5 - 7.01E+06 - - - 0.5923 - 2.751 0.647 - 701.7 1 2 0 0.001 14 0 0 0 5.11E+07 3.15E+07 - - - 6.3589 1 221125_WJC_METTL3_EV_vs_WT_F02.24040.24040.2 8.53E-08 26-Dec R.GFAFVYFENVDDAK[136.11].E "sp|P62995|TRA2B_HUMAN,tr|H7BXF3|H7BXF3_HUMAN" 2 1628.7602 1.62 22698 24040 2 1628.760399 815.3874 Transformer-2 protein homolog beta OS=Homo sapiens OX=9606 GN=TRA2B PE=1 SV=1 4.03 3882.5 - 4.30E+06 - - - 0.1074 - 2.467 0.608 - 444.4 1 2 0 0.0002 14 0 0 0 5.11E+07 3.15E+07 - - - 5.7977 1 221125_WJC_METTL3_EV_vs_WT_F02.24041.24041.3 7.39E-13 19/92 R.AVEFQEAQAYADDNSLLFMETSAK.T "sp|P51148|RAB5C_HUMAN,tr|K7ENY4|K7ENY4_HUMAN" 2 2677.2218 1.33 22699 24041 3 2677.223268 893.4145 Ras-related protein Rab-5C OS=Homo sapiens OX=9606 GN=RAB5C PE=1 SV=2 3.83 3882.6 - 1.87E+06 - - - 0.5621 - 3.709 0.713 - 401.1 1 2 0 0.0015 24 0 0 0 6.17E+06 4.64E+06 - - - 9.5332 0.9998 221125_WJC_METTL3_EV_vs_WT_F02.24042.24042.2 9.11E-07 28-Nov R.ELNSSPQPYLVPFLK.R "sp|O00268|TAF4_HUMAN,tr|A0A0G2JRY5|A0A0G2JRY5_HUMAN" 2 1730.9243 1.07 22700 24042 2 1730.926775 866.4694 Transcription initiation factor TFIID subunit 4 OS=Homo sapiens OX=9606 GN=TAF4 PE=1 SV=2 6.1 3882.7 - 1.53E+06 - - - 1.4166 - 2.091 0.583 - 266.3 1 2 0 0.0025 15 0 0 0 5.33E+06 4.99E+06 - - - 5.1598 1 221125_WJC_METTL3_EV_vs_WT_F02.24043.24043.3 3.02E-08 25/64 K.LTLENFYSNLILQHEER.E "sp|Q9Y2H1|ST38L_HUMAN,tr|F5GY51|F5GY51_HUMAN,tr|F5H7Z3|F5H7Z3_HUMAN,tr|F5H277|F5H277_HUMAN,tr|F5H0V1|F5H0V1_HUMAN,tr|F5H5E6|F5H5E6_HUMAN" 6 2118.0746 4.31 22701 24043 3 2118.077016 707.0321 Serine\threonine-protein kinase 38-like OS=Homo sapiens OX=9606 GN=STK38L PE=1 SV=3 4.75 3882.8 - 1.27E+06 - - - 1.1553 - 4.017 0.46 - 983.1 1 2 0 0.0024 17 0 0 0 1.19E+07 2.76E+06 - - - 7.1808 1 221125_WJC_METTL3_EV_vs_WT_F02.24044.24044.2 1.27E-10 17/30 R.SAFSNLFGGEPLSYTR[166.11].F "sp|P02786|TFR1_HUMAN,tr|F8WBE5|F8WBE5_HUMAN" 2 1754.8503 1.48 22702 24044 2 1754.851218 878.4324 Transferrin receptor protein 1 OS=Homo sapiens OX=9606 GN=TFRC PE=1 SV=2 5.72 3882.9 - 1.07E+06 - - - 0.5117 - 3.53 0.645 - 878.4 1 2 0 0.0009 16 0 0 0 8.35E+06 5.66E+06 - - - 6.9056 1 221125_WJC_METTL3_EV_vs_WT_F02.24045.24045.2 5.36E-09 15/28 K.VIHDNFGIVEGLMTT.V "sp|P04406|G3P_HUMAN,tr|E7EUT5|E7EUT5_HUMAN" 2 1644.8181 - 22703 24045 2 1644.820926 823.4163 Glyceraldehyde-3-phosphate dehydrogenase OS=Homo sapiens OX=9606 GN=GAPDH PE=1 SV=3 4.35 3883 - 704229 - - - 1.692 - 3.04 0.622 - 874 1 1 0 0.0028 15 0 0 0 - - - - - 6.3678 0.9998 221125_WJC_METTL3_EV_vs_WT_F02.24046.24046.2 2.57E-05 16-Oct R.DIDAFWLQR[166.11].Q "sp|O75643|U520_HUMAN,tr|A0A494C1A5|A0A494C1A5_HUMAN" 2 1172.5854 1.7 22704 24046 2 1172.585268 587.3 U5 small nuclear ribonucleoprotein 200 kDa helicase OS=Homo sapiens OX=9606 GN=SNRNP200 PE=1 SV=2 4.21 3883.1 - 643381 - - - -0.0938 - 2.072 0.421 - 365 1 2 0 -0.0001 9 0 0 0 5.99E+06 3.53E+06 - - - 4.2581 1 221125_WJC_METTL3_EV_vs_WT_F02.24048.24048.3 1.68E-08 16/76 K.GLVAVITGGASGLGLATAER[166.11].L "sp|Q99714|HCD2_HUMAN,tr|Q5H928|Q5H928_HUMAN,tr|A0A804HHW5|A0A804HHW5_HUMAN" 3 1822.0188 0.56 22706 24048 3 1822.020077 608.3469 3-hydroxyacyl-CoA dehydrogenase type-2 OS=Homo sapiens OX=9606 GN=HSD17B10 PE=1 SV=3 6 3883.4 - 577779 - - - 0.7108 - 3.236 0.536 - 358.7 1 2 0 0.0013 20 0 0 0 1.29E+06 2.33E+06 - - - 7.3645 1 221125_WJC_METTL3_EV_vs_WT_F02.24049.24049.3 5.96E-08 15/76 K.GLVAVITGGASGLGLATAER.L "sp|Q99714|HCD2_HUMAN,tr|Q5H928|Q5H928_HUMAN,tr|A0A804HHW5|A0A804HHW5_HUMAN" 3 1812.0105 0.56 22707 24049 3 1812.014864 605.0108 3-hydroxyacyl-CoA dehydrogenase type-2 OS=Homo sapiens OX=9606 GN=HSD17B10 PE=1 SV=3 6 3883.5 - 498711 - - - 2.4018 - 2.435 0.588 - 128.9 1 2 0 0.0044 20 0 0 0 1.29E+06 2.33E+06 - - - 7.2534 0.9761 221125_WJC_METTL3_EV_vs_WT_F02.24052.24052.2 2.12E-07 Dec-32 R.VLALSVETDYTFPLAEK.V "sp|P05388|RLA0_HUMAN,tr|F8VWS0|F8VWS0_HUMAN,tr|F8W1K8|F8W1K8_HUMAN,tr|F8VW21|F8VW21_HUMAN,tr|F8VZS0|F8VZS0_HUMAN" 5 1894.9928 -1 22710 24052 2 1896.002596 948.5037 60S acidic ribosomal protein P0 OS=Homo sapiens OX=9606 GN=RPLP0 PE=1 SV=1 4.14 3883.9 - 316375 - - - 532.878 - 2.429 0.593 - 348.6 1 2 0 1.0098 17 0 0 0 0.00E+00 0.00E+00 - - - 5.2857 0.9923 221125_WJC_METTL3_EV_vs_WT_F02.24053.24053.3 0.00165 Dec-72 M.APPSVFAEVPQAQPVLVFK.L sp|P17174|AATC_HUMAN 1 2023.1142 0.43 22711 24053 3 2023.127911 675.3787 "Aspartate aminotransferase, cytoplasmic OS=Homo sapiens OX=9606 GN=GOT1 PE=1 SV=3" 6.05 3884 - 311678 - - - 6.753 - 2.24 0.385 - 113.4 1 2 0 0.0137 19 0 0 0 9.42E+05 2.18E+06 - - - 4.8099 0.9961 221125_WJC_METTL3_EV_vs_WT_F02.24054.24054.2 0.000905 Dec-38 K.GLVAVITGGASGLGLATAER.L "sp|Q99714|HCD2_HUMAN,tr|Q5H928|Q5H928_HUMAN,tr|A0A804HHW5|A0A804HHW5_HUMAN" 3 1812.0105 -1 22712 24054 2 1812.021399 907.0125 3-hydroxyacyl-CoA dehydrogenase type-2 OS=Homo sapiens OX=9606 GN=HSD17B10 PE=1 SV=3 6 3884.1 - 289302 - - - 6.0082 - 2.823 0.492 - 370.6 1 2 0 0.0109 20 0 0 0 0.00E+00 0.00E+00 - - - 5.223 0.9997 221125_WJC_METTL3_EV_vs_WT_F02.24063.24063.2 0.000583 16-Sep R.DIDAFWLQR.Q "sp|O75643|U520_HUMAN,tr|A0A494C1A5|A0A494C1A5_HUMAN" 2 1162.5771 1.7 22719 24063 2 1162.57934 582.2958 U5 small nuclear ribonucleoprotein 200 kDa helicase OS=Homo sapiens OX=9606 GN=SNRNP200 PE=1 SV=2 4.21 3885.2 - 1.21E+06 - - - 1.9199 - 2.036 0.475 - 298.6 1 2 0 0.0022 9 0 0 0 5.99E+06 3.53E+06 - - - 4.6056 0.9835 221125_WJC_METTL3_EV_vs_WT_F02.24064.24064.2 3.70E-06 26-Nov R.SPSELFAQHIVTIV.H "sp|Q9Y2W1|TR150_HUMAN,tr|A0A3B3ITZ9|A0A3B3ITZ9_HUMAN" 2 1539.8297 - 22720 24064 2 1539.832702 770.9221 Thyroid hormone receptor-associated protein 3 OS=Homo sapiens OX=9606 GN=THRAP3 PE=1 SV=2 5.22 3885.3 - 1.12E+06 - - - 1.9535 - 2.291 0.499 - 378.7 1 1 0 0.003 14 0 0 0 - - - - - 4.806 1 221125_WJC_METTL3_EV_vs_WT_F02.24066.24066.3 1.56E-07 16/48 K.KVESLLDELAFVR.Q sp|Q16352|AINX_HUMAN 1 1517.8453 1.76 22722 24066 3 1517.849058 506.9557 Alpha-internexin OS=Homo sapiens OX=9606 GN=INA PE=1 SV=2 4.68 3885.6 - 679998 - - - 2.4469 - 3.184 0.526 - 368.2 1 2 0 0.0037 13 0 0 0 3.10E+06 1.76E+06 - - - 7.5434 1 221125_WJC_METTL3_EV_vs_WT_F02.24067.24067.3 1.75E-05 16/56 K.VSQEILELLNTTTAK[136.11].E "sp|Q86U44|MTA70_HUMAN,tr|H0YFV6|H0YFV6_HUMAN" 2 1666.9233 -1 22723 24067 3 1666.925956 556.6484 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 4.53 3885.7 - 557881 - - - 1.6132 - 3.05 0.487 - 398.5 1 2 0 0.0027 15 0 0 0 0.00E+00 0.00E+00 - - - 6.8786 1 221125_WJC_METTL3_EV_vs_WT_F02.24068.24068.2 9.27E-12 14/30 R.YEDAYQYQNIFGPLVK.L sp|Q92900|RENT1_HUMAN 1 1946.9414 1.02 22724 24068 2 1946.942743 974.478 Regulator of nonsense transcripts 1 OS=Homo sapiens OX=9606 GN=UPF1 PE=1 SV=2 4.37 3885.8 - 463759 - - - 0.6744 - 3.228 0.722 - 473.1 1 2 0 0.0013 16 0 0 0 4.15E+06 4.06E+06 - - - 7.2544 0.9999 221125_WJC_METTL3_EV_vs_WT_F02.24069.24069.3 3.16E-05 Dec-52 R.GFAFVYFENVDDAK[136.11].E "sp|P62995|TRA2B_HUMAN,tr|H7BXF3|H7BXF3_HUMAN" 2 1628.7602 1.33 22725 24069 3 1628.763046 543.9274 Transformer-2 protein homolog beta OS=Homo sapiens OX=9606 GN=TRA2B PE=1 SV=1 4.03 3885.9 - 384433 - - - 1.7326 - 2.168 0.482 - 108.5 1 2 0 0.0028 14 0 0 0 1.43E+06 1.08E+06 - - - 5.9695 0.9999 221125_WJC_METTL3_EV_vs_WT_F02.24070.24070.3 3.64E-05 Dec-44 R.FGMFEFLSNHMR[166.11].D sp|P53007|TXTP_HUMAN 1 1524.6881 0.53 22726 24070 3 1524.686339 509.2367 "Tricarboxylate transport protein, mitochondrial OS=Homo sapiens OX=9606 GN=SLC25A1 PE=1 SV=2" 6.75 3886.1 - 366484 - - - -1.1852 - 2.159 0.418 - 120.1 1 2 0 -0.0018 12 0 0 0 7.47E+05 1.41E+06 - - - 5.3331 0.9997 221125_WJC_METTL3_EV_vs_WT_F02.24071.24071.3 6.99E-05 Nov-72 R.SLGGDVASDGDFLIFEGNR.Y sp|O00267|SPT5H_HUMAN 1 1967.9225 -1 22727 24071 3 1967.917613 656.9814 Transcription elongation factor SPT5 OS=Homo sapiens OX=9606 GN=SUPT5H PE=1 SV=1 3.84 3886.2 - 340832 - - - -2.4757 - 1.961 0.447 - 92.8 1 2 0 -0.0049 19 0 0 0 0.00E+00 0.00E+00 - - - 5.1768 0.9993 221125_WJC_METTL3_EV_vs_WT_F02.24072.24072.3 0.0024 Oct-52 R.GFAFVYFENVDDAK.E "sp|P62995|TRA2B_HUMAN,tr|H7BXF3|H7BXF3_HUMAN" 2 1620.746 1.33 22728 24072 3 1620.750004 541.256 Transformer-2 protein homolog beta OS=Homo sapiens OX=9606 GN=TRA2B PE=1 SV=1 4.03 3886.3 - 336064 - - - 2.4557 - 1.722 0.388 - 72.2 1 2 0 0.004 14 0 0 0 1.43E+06 1.08E+06 - - - 4.309 0.9999 221125_WJC_METTL3_EV_vs_WT_F02.24074.24074.3 1.39E-06 14/64 R.EIISEMGELGVLGPTIK.G "sp|Q92947|GCDH_HUMAN,tr|K7ES74|K7ES74_HUMAN,tr|K7EKT3|K7EKT3_HUMAN" 3 1784.9594 1.68 22730 24074 3 1784.966495 595.9937 "Glutaryl-CoA dehydrogenase, mitochondrial OS=Homo sapiens OX=9606 GN=GCDH PE=1 SV=1" 4.25 3886.6 - 307084 - - - 3.9816 - 2.845 0.574 - 225 1 2 0 0.0071 17 0 0 0 1.25E+06 7.43E+05 - - - 7.579 1 221125_WJC_METTL3_EV_vs_WT_F02.24075.24075.2 1.04E-09 13/30 R.DFPAVPYSGWDFNDGK.C "sp|P0DTE8|AMY1C_HUMAN,sp|P0DTE7|AMY1B_HUMAN,sp|P04746|AMYP_HUMAN,sp|P0DUB6|AMY1A_HUMAN,sp|P19961|AMY2B_HUMAN,tr|H7BZQ8|H7BZQ8_HUMAN,tr|A0A804HHZ3|A0A804HHZ3_HUMAN" 7 1813.7948 9.23 22731 24075 2 1813.804148 907.9047 Alpha-amylase 1C OS=Homo sapiens OX=9606 GN=AMY1C PE=1 SV=1 3.93 3886.7 - 285630 - - - 5.1731 - 2.184 0.689 - 375 1 2 0 0.0094 16 0 0 0 2.40E+06 2.60E+05 - - - 6.0475 0.9999 221125_WJC_METTL3_EV_vs_WT_F02.24077.24077.3 3.74E-06 Dec-64 R.EIISEMGELGVLGPTIK[136.11].G "sp|Q92947|GCDH_HUMAN,tr|K7ES74|K7ES74_HUMAN,tr|K7EKT3|K7EKT3_HUMAN" 3 1792.9736 -1 22733 24077 3 1792.976675 598.6651 "Glutaryl-CoA dehydrogenase, mitochondrial OS=Homo sapiens OX=9606 GN=GCDH PE=1 SV=1" 4.25 3887 - 224266 - - - 1.7217 - 2.442 0.486 - 179 1 2 0 0.0031 17 0 0 0 0.00E+00 0.00E+00 - - - 6.2131 0.9985 221125_WJC_METTL3_EV_vs_WT_F02.24080.24080.2 0.0967 22-Nov R.EAEYFELPELVR[166.11].R sp|Q96CX2|KCD12_HUMAN 1 1503.7485 0.77 22735 24080 2 1503.743297 752.8815 BTB\POZ domain-containing protein KCTD12 OS=Homo sapiens OX=9606 GN=KCTD12 PE=1 SV=1 4.09 3887.5 - 803827 - - - -3.4467 - 2.236 0.362 - 454.3 1 2 0 -0.0052 12 0 0 0 3.29E+06 4.28E+06 - - - 3.8304 1 221125_WJC_METTL3_EV_vs_WT_F02.24082.24082.3 3.33E-10 15/60 K.IHWWENVYGFDMSC[160.03]IK.D "sp|Q99873|ANM1_HUMAN,tr|E9PQ98|E9PQ98_HUMAN,tr|E9PKG1|E9PKG1_HUMAN,tr|H0YDE4|H0YDE4_HUMAN,tr|E9PIX6|E9PIX6_HUMAN" 5 2083.9284 -1 22737 24082 3 2083.93075 695.6501 Protein arginine N-methyltransferase 1 OS=Homo sapiens OX=9606 GN=PRMT1 PE=1 SV=3 5.32 3887.7 - 2.09E+06 - - - 1.109 - 3.034 0.61 - 398.9 1 2 0 0.0023 16 0 0 0 0.00E+00 0.00E+00 - - - 8.1881 1 221125_WJC_METTL3_EV_vs_WT_F02.24086.24086.2 1.85E-10 17/34 R.LSPEPWTPETGLVTDAFK[136.11].L "sp|O60488|ACSL4_HUMAN,sp|O95573|ACSL3_HUMAN,tr|A0A7P0TBB1|A0A7P0TBB1_HUMAN,tr|A0A804HI36|A0A804HI36_HUMAN,tr|A0A7P0TA76|A0A7P0TA76_HUMAN,tr|A0A7P0T8L6|A0A7P0T8L6_HUMAN" 6 1995.0081 3.03 22741 24086 2 1995.010477 998.5113 Long-chain-fatty-acid--CoA ligase 4 OS=Homo sapiens OX=9606 GN=ACSL4 PE=1 SV=2 4.14 3888.1 - 745480 - - - 1.212 - 2.953 0.681 - 577.8 1 2 0 0.0024 18 0 0 0 1.46E+07 4.82E+06 - - - 6.7323 1 221125_WJC_METTL3_EV_vs_WT_F02.24087.24087.2 7.27E-09 17/34 R.LSPEPWTPETGLVTDAFK.L "sp|O60488|ACSL4_HUMAN,sp|O95573|ACSL3_HUMAN,tr|A0A7P0TBB1|A0A7P0TBB1_HUMAN,tr|A0A804HI36|A0A804HI36_HUMAN,tr|A0A7P0TA76|A0A7P0TA76_HUMAN,tr|A0A7P0T8L6|A0A7P0T8L6_HUMAN" 6 1986.9939 3.34 22742 24087 2 1986.994989 994.5042 Long-chain-fatty-acid--CoA ligase 4 OS=Homo sapiens OX=9606 GN=ACSL4 PE=1 SV=2 4.14 3888.2 - 668713 - - - 0.5687 - 2.783 0.617 - 539.5 1 2 0 0.0011 18 0 0 0 1.61E+07 4.82E+06 - - - 6.1142 0.9998 221125_WJC_METTL3_EV_vs_WT_F02.24088.24088.2 1.89E-08 14/30 K.TFVNITPAEVGVLVGK[136.11].D "sp|P07737|PROF1_HUMAN,tr|I3L3D5|I3L3D5_HUMAN" 2 1650.9436 0.67 22743 24088 2 1650.945136 826.4791 Profilin-1 OS=Homo sapiens OX=9606 GN=PFN1 PE=1 SV=2 5.66 3888.4 - 521075 - - - 0.9255 - 3.002 0.421 - 507.7 1 2 0 0.0015 16 0 0 0 1.82E+06 2.70E+06 - - - 4.8527 0.9998 221125_WJC_METTL3_EV_vs_WT_F02.24089.24089.3 0.000104 15/60 R.QNASFLYETVLPVVEK.R sp|Q8IYI6|EXOC8_HUMAN 1 1835.9669 2.01 22744 24089 3 1835.972615 612.9962 Exocyst complex component 8 OS=Homo sapiens OX=9606 GN=EXOC8 PE=1 SV=2 4.53 3888.5 - 472291 - - - 3.1041 - 2.433 0.441 - 222 1 2 0 0.0057 16 0 0 0 6.25E+06 3.11E+06 - - - 5.7365 0.9824 221125_WJC_METTL3_EV_vs_WT_F02.24091.24091.2 5.85E-07 16/38 A.TSILEYPIEPSGVLGAVATK.V "sp|Q96PU8|QKI_HUMAN,tr|H0YG47|H0YG47_HUMAN,tr|H0YGD6|H0YGD6_HUMAN" 3 2044.1092 -1 22746 24091 2 2044.114387 1023.0619 Protein quaking OS=Homo sapiens OX=9606 GN=QKI PE=1 SV=1 4.53 3888.7 - 337517 - - - 2.5263 - 2.761 0.531 - 453.6 1 1 0 0.0052 20 0 0 0 0.00E+00 0.00E+00 - - - 5.4582 1 221125_WJC_METTL3_EV_vs_WT_F02.24093.24093.3 4.02E-07 13/44 R.KGIVLLEELLPK.G sp|Q9Y3D6|FIS1_HUMAN 1 1350.8486 1.58 22748 24093 3 1350.849472 451.2902 Mitochondrial fission 1 protein OS=Homo sapiens OX=9606 GN=FIS1 PE=1 SV=2 6.14 3888.9 - 311076 - - - 0.6166 - 2.69 0.523 - 255.1 1 2 0 0.0008 12 0 0 0 6.62E+06 4.19E+06 - - - 7.1136 1 221125_WJC_METTL3_EV_vs_WT_F02.24096.24096.2 2.04E-09 28-Nov R.LSFSDTYQDYEEYWR.A sp|Q9UHI6|DDX20_HUMAN 1 2000.8428 -1 22751 24096 2 2000.84407 1001.4287 Probable ATP-dependent RNA helicase DDX20 OS=Homo sapiens OX=9606 GN=DDX20 PE=1 SV=2 3.92 3889.3 - 258993 - - - 0.6157 - 2.601 0.669 - 278.3 1 2 0 0.0012 15 0 0 0 0.00E+00 0.00E+00 - - - 6.332 0.9833 221125_WJC_METTL3_EV_vs_WT_F02.24097.24097.2 0.000398 26-Sep N.SLTYSPFGDSPLFR.N "sp|P52948|NUP98_HUMAN,tr|A0A3B3ITD8|A0A3B3ITD8_HUMAN,tr|H0YEN4|H0YEN4_HUMAN,tr|H0YCR0|H0YCR0_HUMAN" 4 1585.7777 -1 22752 24097 2 1585.778002 793.8961 Nuclear pore complex protein Nup98-Nup96 OS=Homo sapiens OX=9606 GN=NUP98 PE=1 SV=4 5.55 3889.5 - 248418 - - - 0.2163 - 1.951 0.4 - 215.8 1 1 0 0.0003 14 0 0 0 0.00E+00 0.00E+00 - - - 3.6725 0.9999 221125_WJC_METTL3_EV_vs_WT_F02.24098.24098.3 1.90E-05 Sep-48 K.HGFLEEFITPIVK.A "sp|Q02880|TOP2B_HUMAN,tr|E9PCY5|E9PCY5_HUMAN" 2 1528.829 999 22753 24098 3 1528.832263 510.6169 DNA topoisomerase 2-beta OS=Homo sapiens OX=9606 GN=TOP2B PE=1 SV=3 5.4 3889.6 - 196696 - - - 2.1566 - 1.91 0.49 - 79.3 1 2 0 0.0033 13 0 0 0 5.29E+05 0.00E+00 - - - 5.7566 0.9984 221125_WJC_METTL3_EV_vs_WT_F02.24099.24099.2 0.693 14-Aug K.ENLLDFIK[136.11].H "sp|P07237|PDIA1_HUMAN,tr|A0A7P0TA97|A0A7P0TA97_HUMAN,tr|A0A7P0T8C0|A0A7P0T8C0_HUMAN,tr|H7BZ94|H7BZ94_HUMAN,tr|A0A7P0TA71|A0A7P0TA71_HUMAN,tr|I3L4M2|I3L4M2_HUMAN,tr|A0A7P0T9D6|A0A7P0T9D6_HUMAN,tr|A0A7P0T9K9|A0A7P0T9K9_HUMAN,tr|H0Y3Z3|H0Y3Z3_HUMAN,tr|A0A7P0Z4S2|A0A7P0Z4S2_HUMAN,tr|A0A7P0TA35|A0A7P0TA35_HUMAN,tr|I3L514|I3L514_HUMAN,tr|A0A7P0TB26|A0A7P0TB26_HUMAN,tr|A0A7P0T9U6|A0A7P0T9U6_HUMAN,tr|I3L0S0|I3L0S0_HUMAN,tr|I3L3P5|I3L3P5_HUMAN,tr|A0A7P0T8J3|A0A7P0T8J3_HUMAN,tr|A0A7P0Z4J0|A0A7P0Z4J0_HUMAN,tr|A0A7P0T8X1|A0A7P0T8X1_HUMAN" 19 998.5528 -1 22754 24099 2 998.553499 500.2837 Protein disulfide-isomerase OS=Homo sapiens OX=9606 GN=P4HB PE=1 SV=3 4.37 3889.7 - 178697 - - - 0.703 - 1.718 0.193 - 205.1 1 2 0 0.0007 8 0 0 0 0.00E+00 0.00E+00 - - - 2.0984 1 221125_WJC_METTL3_EV_vs_WT_F02.24103.24103.3 1.29E-05 22/76 R.QFGFIVLTTSAGIMDHEEAR.R sp|P62244|RS15A_HUMAN 1 2221.0838 0.73 22757 24103 3 2221.081493 741.3685 40S ribosomal protein S15a OS=Homo sapiens OX=9606 GN=RPS15A PE=1 SV=2 4.65 3890.1 - 5.63E+06 - - - -1.018 - 3.864 0.646 - 687.3 1 2 0 -0.0023 20 0 0 0 1.71E+07 2.36E+07 - - - 9.0209 0.9724 221125_WJC_METTL3_EV_vs_WT_F02.24105.24105.2 1.93 26-May K.KMSDNNNGLTEVLK.E "sp|Q9H792|PEAK1_HUMAN,tr|H3BUZ5|H3BUZ5_HUMAN,tr|H0YN99|H0YN99_HUMAN" 3 1561.777 370.55 22759 24105 2 1561.778466 781.8958 Inactive tyrosine-protein kinase PEAK1 OS=Homo sapiens OX=9606 GN=PEAK1 PE=1 SV=4 6.07 3890.2 - 3.93E+06 - - - 0.9342 - 1.011 0.159 - 35.9 2 2 0 0.0015 14 0 0 0 5.37E+07 1.45E+05 - - - 0.1079 1 221125_WJC_METTL3_EV_vs_WT_F02.24107.24107.3 1.13E-05 Nov-68 K.LEGVLAEVAQHYQDTLIR.A "sp|P46940|IQGA1_HUMAN,tr|A0A0J9YXZ5|A0A0J9YXZ5_HUMAN" 2 2054.0797 -1 22761 24107 3 2054.079969 685.7005 Ras GTPase-activating-like protein IQGAP1 OS=Homo sapiens OX=9606 GN=IQGAP1 PE=1 SV=1 4.65 3890.3 - 2.25E+06 - - - 0.1534 - 2.469 0.543 - 130.9 1 2 0 0.0003 18 0 0 0 0.00E+00 0.00E+00 - - - 6.8444 1 221125_WJC_METTL3_EV_vs_WT_F02.24108.24108.2 2.46E-05 15/30 K.TYLISSIPLQGAFNYK.Y sp|P12273|PIP_HUMAN 1 1813.9614 138.62 22762 24108 2 1813.958196 907.988 Prolactin-inducible protein OS=Homo sapiens OX=9606 GN=PIP PE=1 SV=1 8.17 3890.3 - 1.96E+06 - - - -1.7867 - 2.86 0.597 - 479.7 1 2 0 -0.0032 16 0 0 0 6.95E+07 5.01E+05 - - - 6.0329 0.9805 221125_WJC_METTL3_EV_vs_WT_F02.24109.24109.2 0.00647 18-Sep R.QNLEPLFEQY.L "sp|P48668|K2C6C_HUMAN,sp|P04259|K2C6B_HUMAN,sp|P13647|K2C5_HUMAN,sp|P02538|K2C6A_HUMAN,tr|F8W0C6|F8W0C6_HUMAN" 5 1279.6085 - 22763 24109 2 1279.608154 640.8115 "Keratin, type II cytoskeletal 6C OS=Homo sapiens OX=9606 GN=KRT6C PE=1 SV=3" 3.79 3890.4 - 1.88E+06 - - - -0.2454 - 1.834 0.369 - 232 1 1 0 -0.0003 10 0 0 0 - - - - - 3.4593 0.9992 221125_WJC_METTL3_EV_vs_WT_F02.24112.24112.2 8.19E-10 15/30 R.FSNTGEDWYVLVGVAK[136.11].D sp|Q15393|SF3B3_HUMAN 1 1791.8923 1.3 22766 24112 2 1791.891622 896.9534 Splicing factor 3B subunit 3 OS=Homo sapiens OX=9606 GN=SF3B3 PE=1 SV=4 4.37 3890.6 - 1.08E+06 - - - -0.3789 - 2.886 0.133 - 759.6 1 2 0 -0.0007 16 0 0 0 1.54E+07 1.18E+07 - - - 2.6289 0.9965 221125_WJC_METTL3_EV_vs_WT_F02.24116.24116.3 3.63E-08 13/76 R.GFEVVYMTEPIDEYC[160.03]VQQLK[136.11].E "sp|P08238|HS90B_HUMAN,sp|Q58FF7|H90B3_HUMAN" 2 2455.1531 1.02 22770 24116 3 2456.146267 819.3916 Heat shock protein HSP 90-beta OS=Homo sapiens OX=9606 GN=HSP90AB1 PE=1 SV=4 4 3890.9 - 681201 - - - 404.5292 - 3.116 0.593 - 209.2 1 2 0 0.9932 20 0 0 0 5.60E+06 5.49E+06 - - - 7.6335 1 221125_WJC_METTL3_EV_vs_WT_F02.24118.24118.2 9.07E-09 15/32 R.TLLFTFNVPGSGNTYPK.D "sp|Q96A33|CCD47_HUMAN,tr|A0A087WYW6|A0A087WYW6_HUMAN" 2 1854.9516 1.31 22772 24118 2 1854.949955 928.4831 PAT complex subunit CCDC47 OS=Homo sapiens OX=9606 GN=CCDC47 PE=1 SV=1 8.26 3891.1 - 603919 - - - -0.8868 - 2.946 0.58 - 421.5 1 2 0 -0.0016 17 0 0 0 3.59E+06 2.74E+06 - - - 5.9807 0.9974 221125_WJC_METTL3_EV_vs_WT_F02.24120.24120.3 4.60E-08 16/64 N.QSLLTPLNLQIDPTIQR.V sp|P02538|K2C6A_HUMAN 1 1949.0946 13.91 22774 24120 3 1949.091751 650.7055 "Keratin, type II cytoskeletal 6A OS=Homo sapiens OX=9606 GN=KRT6A PE=1 SV=3" 5.84 3891.2 - 353459 - - - -1.4494 - 2.852 0.528 - 231.6 1 1 0 -0.0028 17 0 0 0 3.83E+06 2.75E+05 - - - 7.0735 0.9996 221125_WJC_METTL3_EV_vs_WT_F02.24123.24123.2 0.000416 20-Nov R.DYNLVPAFLGK.D sp|Q86TJ2|TAD2B_HUMAN 1 1235.655 1.2 22776 24123 2 1235.654542 618.8348 Transcriptional adapter 2-beta OS=Homo sapiens OX=9606 GN=TADA2B PE=1 SV=2 5.83 3891.6 - 561274 - - - -0.3901 - 1.715 0.394 - 243.9 1 2 0 -0.0005 11 0 0 0 3.10E+06 2.58E+06 - - - 3.4102 1 221125_WJC_METTL3_EV_vs_WT_F02.24124.24124.3 2.29E-13 36/80 R.IPLNPYLNLHSLLPASNLAGK[136.11].E "tr|E9PAU2|E9PAU2_HUMAN,tr|A0A087WZ13|A0A087WZ13_HUMAN" 2 2252.2772 1.02 22777 24124 3 2252.278222 751.7664 Ribonucleoprotein PTB-binding 1 OS=Homo sapiens OX=9606 GN=RAVER1 PE=1 SV=1 8.6 3891.7 - 4.66E+06 - - - 0.4364 - 6.01 0.647 - 1526.7 1 2 0 0.001 21 0 0 0 6.67E+07 6.52E+07 - - - 10.0528 1 221125_WJC_METTL3_EV_vs_WT_F02.24125.24125.3 6.94E-09 34/80 R.IPLNPYLNLHSLLPASNLAGK.E "tr|E9PAU2|E9PAU2_HUMAN,tr|A0A087WZ13|A0A087WZ13_HUMAN" 2 2244.263 1.02 22778 24125 3 2244.26504 749.095 Ribonucleoprotein PTB-binding 1 OS=Homo sapiens OX=9606 GN=RAVER1 PE=1 SV=1 8.6 3891.8 - 4.53E+06 - - - 0.8916 - 5.42 0.659 - 1206.1 1 2 0 0.002 21 0 0 0 6.67E+07 6.52E+07 - - - 9.9386 0.9985 221125_WJC_METTL3_EV_vs_WT_F02.24126.24126.3 1.10E-09 20/88 K.SPLPTPGAPVPVPAATGPYYSPY.A sp|Q96F45|ZN503_HUMAN 1 2298.1572 - 22779 24126 3 2298.159874 767.0597 Zinc finger protein 503 OS=Homo sapiens OX=9606 GN=ZNF503 PE=1 SV=1 5.24 3891.8 - 3.15E+06 - - - 1.1479 - 3.167 0.597 - 223.3 1 1 0 0.0026 23 0 0 0 - - - - - 7.8996 1 221125_WJC_METTL3_EV_vs_WT_F02.24129.24129.3 1.02E-11 18/76 R.GFEVVYMTEPIDEYC[160.03]VQQLK.E "sp|P08238|HS90B_HUMAN,sp|Q58FF7|H90B3_HUMAN" 2 2447.1389 1.02 22782 24129 3 2447.138409 816.7202 Heat shock protein HSP 90-beta OS=Homo sapiens OX=9606 GN=HSP90AB1 PE=1 SV=4 4 3892.1 - 1.57E+06 - - - -0.1949 - 3.638 0.645 - 481.2 1 2 0 -0.0005 20 0 0 0 5.60E+06 5.49E+06 - - - 8.864 1 221125_WJC_METTL3_EV_vs_WT_F02.24130.24130.3 3.70E-07 20/68 R.NEEDAAELVALAQAVNAR[166.11].A sp|P22314|UBA1_HUMAN 1 1892.9467 -1 22783 24130 3 1892.949123 631.9895 Ubiquitin-like modifier-activating enzyme 1 OS=Homo sapiens OX=9606 GN=UBA1 PE=1 SV=3 4 3892.2 - 1.30E+06 - - - 1.2594 - 3.426 0.571 - 517.7 1 2 0 0.0024 18 0 0 0 0.00E+00 0.00E+00 - - - 7.9717 1 221125_WJC_METTL3_EV_vs_WT_F02.24131.24131.3 2.95E-09 22/68 K.LPNGLVIASLENYSPVSR.L "sp|P22695|QCR2_HUMAN,tr|H3BP04|H3BP04_HUMAN,tr|H3BUE4|H3BUE4_HUMAN,tr|H3BUI9|H3BUI9_HUMAN,tr|H3BRG4|H3BRG4_HUMAN,tr|H3BSJ9|H3BSJ9_HUMAN" 6 1928.0367 2.18 22784 24131 3 1928.041471 643.6862 "Cytochrome b-c1 complex subunit 2, mitochondrial OS=Homo sapiens OX=9606 GN=UQCRC2 PE=1 SV=3" 6 3892.3 - 1.26E+06 - - - 2.4605 - 3.372 0.543 - 628.1 1 2 0 0.0047 18 0 0 0 9.32E+06 4.27E+06 - - - 7.6193 1 221125_WJC_METTL3_EV_vs_WT_F02.24132.24132.2 3.36E-16 24/44 K.SPLPTPGAPVPVPAATGPYYSPY.A sp|Q96F45|ZN503_HUMAN 1 2298.1572 - 22785 24132 2 2298.159332 1150.0859 Zinc finger protein 503 OS=Homo sapiens OX=9606 GN=ZNF503 PE=1 SV=1 5.24 3892.5 - 1.15E+06 - - - 0.912 - 3.862 0.746 - 783.5 1 1 0 0.0021 23 0 0 0 - - - - - 7.8722 0.9951 221125_WJC_METTL3_EV_vs_WT_F02.24133.24133.3 1.70E-07 16/56 K.VEDLTFTSPFC[160.03]LQVK[136.11].R "sp|Q99873|ANM1_HUMAN,tr|E9PKG1|E9PKG1_HUMAN" 2 1790.9004 2.52 22786 24133 3 1791.898336 597.9741 Protein arginine N-methyltransferase 1 OS=Homo sapiens OX=9606 GN=PRMT1 PE=1 SV=3 4.37 3892.6 - 1.03E+06 - - - 557.213 - 2.914 0.447 - 429.4 1 2 0 0.9979 15 0 0 0 6.79E+06 2.69E+06 - - - 6.038 1 221125_WJC_METTL3_EV_vs_WT_F02.24140.24140.2 3.67E-09 14/32 R.EIINTYTEAVQTVDPFK[136.11].A sp|Q9HCS7|SYF1_HUMAN 1 1975.003 -1 22793 24140 2 1975.010141 988.5088 Pre-mRNA-splicing factor SYF1 OS=Homo sapiens OX=9606 GN=XAB2 PE=1 SV=2 4.14 3893.5 - 503683 - - - 3.6289 - 2.792 0.6 - 438.7 1 2 0 0.0072 17 0 0 0 0.00E+00 0.00E+00 - - - 5.9947 1 221125_WJC_METTL3_EV_vs_WT_F02.24143.24143.3 0.0313 Dec-44 R.K[136.11]GIVLLEELLPK[136.11].G sp|Q9Y3D6|FIS1_HUMAN 1 1366.877 1.58 22795 24143 3 1366.878296 456.633 Mitochondrial fission 1 protein OS=Homo sapiens OX=9606 GN=FIS1 PE=1 SV=2 6.14 3893.8 - 354746 - - - 0.9196 - 2.587 0.477 - 235.1 1 2 0 0.0013 12 0 0 0 6.62E+06 4.19E+06 - - - 6.4924 1 221125_WJC_METTL3_EV_vs_WT_F02.24144.24144.2 1.88E-11 20/34 K.LPNGLVIASLENYSPVSR[166.11].L "sp|P22695|QCR2_HUMAN,tr|H3BP04|H3BP04_HUMAN,tr|H3BUE4|H3BUE4_HUMAN,tr|H3BUI9|H3BUI9_HUMAN,tr|H3BRG4|H3BRG4_HUMAN,tr|H3BSJ9|H3BSJ9_HUMAN" 6 1938.045 -1 22796 24144 2 1938.045406 970.0298 "Cytochrome b-c1 complex subunit 2, mitochondrial OS=Homo sapiens OX=9606 GN=UQCRC2 PE=1 SV=3" 6 3894 - 830738 - - - 0.211 - 3.638 0.659 - 1279.8 1 2 0 0.0004 18 0 0 0 0.00E+00 0.00E+00 - - - 7.0833 0.9999 221125_WJC_METTL3_EV_vs_WT_F02.24145.24145.3 6.85E-06 Oct-60 K.TYLISSIPLQGAFNYK.Y sp|P12273|PIP_HUMAN 1 1813.9614 63.86 22797 24145 3 1813.958483 605.6611 Prolactin-inducible protein OS=Homo sapiens OX=9606 GN=PIP PE=1 SV=1 8.17 3894 - 6.42E+06 - - - -1.6285 - 1.952 0.485 - 106.8 1 2 0 -0.003 16 0 0 0 1.92E+07 3.01E+05 - - - 5.6626 1 221125_WJC_METTL3_EV_vs_WT_F02.24146.24146.3 4.87E-09 15/64 K.ALEFIPSDQQVINEMVR.E "tr|Q5T1Z8|Q5T1Z8_HUMAN,tr|H0YDK8|H0YDK8_HUMAN,tr|H0YC97|H0YC97_HUMAN,tr|Q5T1Z4|Q5T1Z4_HUMAN" 4 1988.0037 2.58 22798 24146 3 1988.002239 663.6752 Pumilio homolog 1 OS=Homo sapiens OX=9606 GN=PUM1 PE=1 SV=1 4.14 3894 - 4.07E+06 - - - -0.7409 - 3.197 0.609 - 352 1 2 0 -0.0015 17 0 0 0 2.14E+07 8.30E+06 - - - 8.2654 0.9996 221125_WJC_METTL3_EV_vs_WT_F02.24148.24148.3 7.41E-05 Sep-56 K.TTQVTQFILDNYIER.G "sp|Q9H2U1|DHX36_HUMAN,tr|E7EWK3|E7EWK3_HUMAN" 2 1839.9367 1.23 22800 24148 3 1839.932838 614.3195 ATP-dependent DNA\RNA helicase DHX36 OS=Homo sapiens OX=9606 GN=DHX36 PE=1 SV=2 4.37 3894.1 - 2.43E+06 - - - -2.0876 - 2.006 0.382 - 101.6 1 2 0 -0.0038 15 0 0 0 6.29E+06 5.11E+06 - - - 4.6143 0.9856 221125_WJC_METTL3_EV_vs_WT_F02.24149.24149.3 6.08E-05 Oct-44 R.NIETIINTFHQY.S sp|P06702|S10A9_HUMAN 1 1491.7358 - 22801 24149 3 1491.733812 498.2525 Protein S100-A9 OS=Homo sapiens OX=9606 GN=S100A9 PE=1 SV=1 5.24 3894.2 - 1.98E+06 - - - -1.3287 - 1.864 0.428 - 129.2 1 1 0 -0.002 12 0 0 0 - - - - - 5.0373 1 221125_WJC_METTL3_EV_vs_WT_F02.24152.24152.2 6.25E-08 15/34 R.QTLSTPGTIILGTIPVPK[136.11].G "sp|Q9BSD7|NTPCR_HUMAN,tr|Q5TDF0|Q5TDF0_HUMAN" 2 1843.091 1.21 22804 24152 2 1843.081181 922.5528 Cancer-related nucleoside-triphosphatase OS=Homo sapiens OX=9606 GN=NTPCR PE=1 SV=1 8.75 3894.3 - 1.71E+06 - - - -5.328 - 3.108 0.635 - 538.2 1 2 0 -0.0098 18 0 0 0 2.36E+08 1.95E+08 - - - 6.516 0.9999 221125_WJC_METTL3_EV_vs_WT_F02.24153.24153.2 2.39E-06 14/34 R.QTLSTPGTIILGTIPVPK.G "sp|Q9BSD7|NTPCR_HUMAN,tr|Q5TDF0|Q5TDF0_HUMAN" 2 1835.0768 1.21 22805 24153 2 1835.076246 918.5457 Cancer-related nucleoside-triphosphatase OS=Homo sapiens OX=9606 GN=NTPCR PE=1 SV=1 8.75 3894.4 - 1.65E+06 - - - -0.3024 - 2.757 0.565 - 435 1 2 0 -0.0006 18 0 0 0 2.36E+08 1.95E+08 - - - 5.7072 1 221125_WJC_METTL3_EV_vs_WT_F02.24155.24155.2 3.52E-11 19/34 K.LPNGLVIASLENYSPVSR.L "sp|P22695|QCR2_HUMAN,tr|H3BP04|H3BP04_HUMAN,tr|H3BUE4|H3BUE4_HUMAN,tr|H3BUI9|H3BUI9_HUMAN,tr|H3BRG4|H3BRG4_HUMAN,tr|H3BSJ9|H3BSJ9_HUMAN" 6 1928.0367 -1 22807 24155 2 1928.032723 965.0256 "Cytochrome b-c1 complex subunit 2, mitochondrial OS=Homo sapiens OX=9606 GN=UQCRC2 PE=1 SV=3" 6 3894.6 - 1.28E+06 - - - -2.0767 - 3.761 0.685 - 1132.6 1 2 0 -0.004 18 0 0 0 0.00E+00 0.00E+00 - - - 7.356 1 221125_WJC_METTL3_EV_vs_WT_F02.24157.24157.2 9.65E-11 15/38 R.GFEVVYMTEPIDEYC[160.03]VQQLK[136.11].E "sp|P08238|HS90B_HUMAN,sp|Q58FF7|H90B3_HUMAN" 2 2455.1531 -1 22809 24157 2 2455.154415 1228.5838 Heat shock protein HSP 90-beta OS=Homo sapiens OX=9606 GN=HSP90AB1 PE=1 SV=4 4 3894.8 - 0 - - - 0.5413 - 3.386 0.685 - 593.5 1 2 0 0.0013 20 0 0 0 0.00E+00 0.00E+00 - - - 7.0986 0.9948 221125_WJC_METTL3_EV_vs_WT_F02.24166.24166.2 7.08E-06 22-Nov R.NIETIINTFHQY.S sp|P06702|S10A9_HUMAN 1 1491.7358 - 22816 24166 2 1491.735178 746.8752 Protein S100-A9 OS=Homo sapiens OX=9606 GN=S100A9 PE=1 SV=1 5.24 3896 - 1.12E+07 - - - -0.4129 - 2.48 0.565 - 267.7 1 1 0 -0.0006 12 0 0 0 - - - - - 5.6037 0.9999 221125_WJC_METTL3_EV_vs_WT_F02.24167.24167.2 4.02E-07 16/26 R.DALPELLGLEAGSR.R "sp|Q9NSI2|SLX9_HUMAN,tr|C9JJU7|C9JJU7_HUMAN" 2 1439.762 1.74 22817 24167 2 1439.761753 720.8883 Ribosome biogenesis protein SLX9 homolog OS=Homo sapiens OX=9606 GN=SLX9 PE=1 SV=2 4.14 3896 - 9.51E+06 - - - -0.1778 - 2.413 0.554 - 826.3 1 2 0 -0.0003 14 0 0 0 1.15E+08 6.58E+07 - - - 5.3433 1 221125_WJC_METTL3_EV_vs_WT_F02.24168.24168.3 2.22E-07 17/68 R.FLSQPFQVAEVFTGHMGK.L sp|P06576|ATPB_HUMAN 1 2022.0033 1.5 22818 24168 3 2022.004584 675.0084 "ATP synthase subunit beta, mitochondrial OS=Homo sapiens OX=9606 GN=ATP5F1B PE=1 SV=3" 6.75 3896 - 7.76E+06 - - - 0.6261 - 3.093 0.574 - 245.3 1 2 0 0.0013 18 0 0 0 3.52E+07 2.35E+07 - - - 7.7509 0.9997 221125_WJC_METTL3_EV_vs_WT_F02.24170.24170.3 7.21E-05 18/68 R.FLSQPFQVAEVFTGHMGK[136.11].L sp|P06576|ATPB_HUMAN 1 2030.0175 1.57 22820 24170 3 2030.0172 677.6798 "ATP synthase subunit beta, mitochondrial OS=Homo sapiens OX=9606 GN=ATP5F1B PE=1 SV=3" 6.75 3896.1 - 4.60E+06 - - - -0.1566 - 2.182 0.344 - 210.3 1 2 0 -0.0003 18 0 0 0 4.41E+07 2.81E+07 - - - 4.3181 1 221125_WJC_METTL3_EV_vs_WT_F02.24171.24171.3 1.46E-07 Dec-68 R.QTLSTPGTIILGTIPVPK[136.11].G "sp|Q9BSD7|NTPCR_HUMAN,tr|Q5TDF0|Q5TDF0_HUMAN" 2 1843.091 1.21 22821 24171 3 1843.091137 615.3709 Cancer-related nucleoside-triphosphatase OS=Homo sapiens OX=9606 GN=NTPCR PE=1 SV=1 8.75 3896.2 - 3.71E+06 - - - 0.0738 - 2.523 0.519 - 111.4 1 2 0 0.0001 18 0 0 0 2.21E+08 1.83E+08 - - - 6.6308 0.9999 221125_WJC_METTL3_EV_vs_WT_F02.24172.24172.3 0.000102 Oct-68 R.QTLSTPGTIILGTIPVPK.G "sp|Q9BSD7|NTPCR_HUMAN,tr|Q5TDF0|Q5TDF0_HUMAN" 2 1835.0768 1.21 22822 24172 3 1835.0777 612.6995 Cancer-related nucleoside-triphosphatase OS=Homo sapiens OX=9606 GN=NTPCR PE=1 SV=1 8.75 3896.2 - 3.57E+06 - - - 0.4899 - 2.267 0.448 - 83.2 1 2 0 0.0009 18 0 0 0 2.21E+08 1.83E+08 - - - 5.5725 1 221125_WJC_METTL3_EV_vs_WT_F02.24174.24174.3 6.18E-08 18/76 K.SVNESLNNLFITEEDYQALR[166.11].T "sp|Q00610|CLH1_HUMAN,tr|K7EJJ5|K7EJJ5_HUMAN,tr|J3KS13|J3KS13_HUMAN,tr|A0A087WVQ6|A0A087WVQ6_HUMAN" 4 2364.1473 0.53 22824 24174 3 2364.147771 789.0564 Clathrin heavy chain 1 OS=Homo sapiens OX=9606 GN=CLTC PE=1 SV=5 4 3896.4 - 2.53E+06 - - - 0.2035 - 3.191 0.562 - 447 1 2 0 0.0005 20 0 0 0 7.70E+06 1.45E+07 - - - 7.6206 0.9999 221125_WJC_METTL3_EV_vs_WT_F02.24175.24175.3 5.23E-05 17/56 K.EISLWFK[136.11]PEELVDYK[136.11].S "sp|P22392|NDKB_HUMAN,tr|Q32Q12|Q32Q12_HUMAN" 2 1911.0001 1.41 22825 24175 3 1910.996634 638.0073 Nucleoside diphosphate kinase B OS=Homo sapiens OX=9606 GN=NME2 PE=1 SV=1 4.41 3896.4 - 1.68E+06 - - - -1.7964 - 2.555 0.471 - 347.7 1 2 0 -0.0034 15 0 0 0 2.35E+07 1.67E+07 - - - 6.238 1 221125_WJC_METTL3_EV_vs_WT_F02.24176.24176.3 9.49E-16 24/92 R.SYLAPGLLQGQVAIVTGGATGIGK.A "sp|Q9BY49|PECR_HUMAN,tr|B4DJS2|B4DJS2_HUMAN" 2 2270.2634 1.32 22826 24176 3 2270.264548 757.7618 Peroxisomal trans-2-enoyl-CoA reductase OS=Homo sapiens OX=9606 GN=PECR PE=1 SV=2 8.31 3896.5 - 1.58E+06 - - - 0.4911 - 4.15 0.699 - 555.5 1 2 0 0.0011 24 0 0 0 7.49E+06 5.66E+06 - - - 9.6382 1 221125_WJC_METTL3_EV_vs_WT_F02.24177.24177.3 1.95E-07 26/88 K.LDIISPQLSSASLLTPQSAEC[160.03]LR.A "sp|Q15643|TRIPB_HUMAN,tr|H0YJ97|H0YJ97_HUMAN" 2 2498.305 1.12 22827 24177 3 2498.306148 833.7756 Thyroid receptor-interacting protein 11 OS=Homo sapiens OX=9606 GN=TRIP11 PE=1 SV=3 4.37 3896.7 - 1.57E+06 - - - 0.4435 - 4.397 0.611 - 498.7 1 2 0 0.0011 23 0 0 0 1.59E+07 1.42E+07 - - - 8.8259 0.9565 221125_WJC_METTL3_EV_vs_WT_F02.24178.24178.2 0.000733 28-Oct K.VEDLTFTSPFC[160.03]LQVK.R "sp|Q99873|ANM1_HUMAN,tr|E9PKG1|E9PKG1_HUMAN" 2 1782.8862 3.78 22828 24178 2 1783.891281 892.4504 Protein arginine N-methyltransferase 1 OS=Homo sapiens OX=9606 GN=PRMT1 PE=1 SV=3 4.37 3896.7 - 1.50E+06 - - - 563.7253 - 1.62 0.352 - 144.4 1 2 0 1.0051 15 0 0 0 2.06E+07 5.45E+06 - - - 2.5114 1 221125_WJC_METTL3_EV_vs_WT_F02.24179.24179.3 9.84E-07 22/88 K.LDIISPQLSSASLLTPQSAEC[160.03]LR[166.11].A "sp|Q15643|TRIPB_HUMAN,tr|H0YJ97|H0YJ97_HUMAN" 2 2508.3133 1.12 22829 24179 3 2508.31417 837.1117 Thyroid receptor-interacting protein 11 OS=Homo sapiens OX=9606 GN=TRIP11 PE=1 SV=3 4.37 3896.8 - 1.40E+06 - - - 0.3429 - 3.356 0.54 - 353.4 1 2 0 0.0009 23 0 0 0 1.59E+07 1.42E+07 - - - 7.4006 0.9998 221125_WJC_METTL3_EV_vs_WT_F02.24180.24180.2 5.90E-05 13/24 K.ELAGALAYIMDNK[136.11].L "sp|Q14527|HLTF_HUMAN,tr|A0A0C4DGA6|A0A0C4DGA6_HUMAN" 2 1415.721 1.51 22830 24180 2 1415.718811 708.8678 Helicase-like transcription factor OS=Homo sapiens OX=9606 GN=HLTF PE=1 SV=2 4.37 3896.9 - 1.34E+06 - - - -1.5476 - 2.563 0.494 - 486.2 1 2 0 -0.0022 13 0 0 0 1.01E+07 6.68E+06 - - - 5.1046 1 221125_WJC_METTL3_EV_vs_WT_F02.24181.24181.3 1.35E-05 19/52 R.DALPELLGLEAGSR.R "sp|Q9NSI2|SLX9_HUMAN,tr|C9JJU7|C9JJU7_HUMAN" 2 1439.762 1.99 22831 24181 3 1439.762066 480.9279 Ribosome biogenesis protein SLX9 homolog OS=Homo sapiens OX=9606 GN=SLX9 PE=1 SV=2 4.14 3897 - 1.31E+06 - - - 0.0396 - 2.856 0.474 - 623.5 1 2 0 0.0001 14 0 0 0 1.43E+07 7.17E+06 - - - 6.6135 1 221125_WJC_METTL3_EV_vs_WT_F02.24183.24183.3 1.79E-06 19/80 K.EPFELEAFYTNLHEVPYPDAR[166.11].L "sp|O95757|HS74L_HUMAN,tr|D6RJ96|D6RJ96_HUMAN,tr|E9PDE8|E9PDE8_HUMAN" 3 2546.1993 -1 22833 24183 3 2546.202643 849.7404 Heat shock 70 kDa protein 4L OS=Homo sapiens OX=9606 GN=HSPA4L PE=1 SV=3 4.25 3897.3 - 983403 - - - 1.3031 - 3.018 0.532 - 260.1 1 2 0 0.0033 21 0 0 0 0.00E+00 0.00E+00 - - - 7.1186 0.9998 221125_WJC_METTL3_EV_vs_WT_F02.24184.24184.2 0.000161 18-Sep K.FAAQELIEVK[136.11].R "sp|Q86U44|MTA70_HUMAN,tr|F5H6D8|F5H6D8_HUMAN,tr|H0YFV6|H0YFV6_HUMAN,tr|B4DTN4|B4DTN4_HUMAN" 4 1154.6427 0.001 22834 24184 2 1154.643808 578.3286 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 4.53 3897.4 - 877038 - - - 0.9813 - 1.933 0.445 - 187.6 1 2 0 0.0011 10 0 0 0 0.00E+00 5.15E+06 - - - 4.1671 0.9986 221125_WJC_METTL3_EV_vs_WT_F02.24187.24187.3 1.39 15/68 K.SAPWNSFLPPPPPMPGPR.L "sp|Q16637|SMN_HUMAN,tr|E7EQZ4|E7EQZ4_HUMAN,tr|H0YBZ9|H0YBZ9_HUMAN,tr|B4DP61|B4DP61_HUMAN,tr|A0A0G2JRX5|A0A0G2JRX5_HUMAN,tr|A0A1W2PRV5|A0A1W2PRV5_HUMAN,tr|A0A0G2JRY6|A0A0G2JRY6_HUMAN" 7 1943.9716 10.54 22836 24187 3 1943.976594 648.9978 Survival motor neuron protein OS=Homo sapiens OX=9606 GN=SMN1 PE=1 SV=1 9.47 3897.8 - 621808 - - - 2.5566 - 2.626 0.258 - 210.4 1 2 0 0.005 18 0 0 0 3.92E+06 3.72E+05 - - - 3.8192 0.9943 221125_WJC_METTL3_EV_vs_WT_F02.24190.24190.2 3.85E-08 16/28 A.QGGVLPNIQAVLLPK.K "sp|P16104|H2AX_HUMAN,sp|Q9BTM1|H2AJ_HUMAN,sp|Q93077|H2A1C_HUMAN,sp|Q99878|H2A1J_HUMAN,sp|Q16777|H2A2C_HUMAN,sp|Q8IUE6|H2A2B_HUMAN,sp|Q96QV6|H2A1A_HUMAN,sp|P04908|H2A1B_HUMAN,sp|P20671|H2A1D_HUMAN,sp|P0C0S8|H2A1_HUMAN,sp|Q6FI13|H2A2A_HUMAN,sp|Q96KK5|H2A1H_HUMAN,sp|Q7L7L0|H2A3_HUMAN,tr|A0A0U1RR32|A0A0U1RR32_HUMAN,tr|A0A0U1RRH7|A0A0U1RRH7_HUMAN,tr|H0YFX9|H0YFX9_HUMAN" 16 1545.9243 1.37 22839 24190 2 1545.924937 773.9694 Histone H2AX OS=Homo sapiens OX=9606 GN=H2AX PE=1 SV=2 8.75 3898.1 - 3.20E+06 - - - 0.436 - 2.591 0.554 - 806.4 1 1 0 0.0007 15 0 0 0 1.83E+07 1.34E+07 - - - 5.4733 1 221125_WJC_METTL3_EV_vs_WT_F02.24191.24191.2 0.000345 17/28 K.EISLWFK[136.11]PEELVDYK[136.11].S "sp|P22392|NDKB_HUMAN,tr|Q32Q12|Q32Q12_HUMAN" 2 1911.0001 -1 22840 24191 2 1911.000132 956.5073 Nucleoside diphosphate kinase B OS=Homo sapiens OX=9606 GN=NME2 PE=1 SV=1 4.41 3898.2 - 2.85E+06 - - - 0.034 - 3.396 0.537 - 999.1 1 2 0 0.0001 15 0 0 0 0.00E+00 0.00E+00 - - - 6.0131 1 221125_WJC_METTL3_EV_vs_WT_F02.24192.24192.3 1.68E-10 21/72 R.ILQEAQNLMALTNVDTPLK.G sp|Q99459|CDC5L_HUMAN 1 2111.1296 1.38 22841 24192 3 2111.131316 704.7172 Cell division cycle 5-like protein OS=Homo sapiens OX=9606 GN=CDC5L PE=1 SV=2 4.37 3898.3 - 2.85E+06 - - - 0.7934 - 3.555 0.522 - 593.4 1 2 0 0.0017 19 0 0 0 1.11E+07 8.04E+06 - - - 7.4754 0.989 221125_WJC_METTL3_EV_vs_WT_F02.24193.24193.2 1.31E-05 14/28 A.QGGVLPNIQAVLLPK[136.11].K "sp|P16104|H2AX_HUMAN,sp|Q9BTM1|H2AJ_HUMAN,sp|Q93077|H2A1C_HUMAN,sp|Q99878|H2A1J_HUMAN,sp|Q16777|H2A2C_HUMAN,sp|Q8IUE6|H2A2B_HUMAN,sp|Q96QV6|H2A1A_HUMAN,sp|P04908|H2A1B_HUMAN,sp|P20671|H2A1D_HUMAN,sp|P0C0S8|H2A1_HUMAN,sp|Q6FI13|H2A2A_HUMAN,sp|Q96KK5|H2A1H_HUMAN,sp|Q7L7L0|H2A3_HUMAN,tr|A0A0U1RR32|A0A0U1RR32_HUMAN,tr|A0A0U1RRH7|A0A0U1RRH7_HUMAN,tr|H0YFX9|H0YFX9_HUMAN" 16 1553.9385 1.37 22842 24193 2 1553.936313 777.9765 Histone H2AX OS=Homo sapiens OX=9606 GN=H2AX PE=1 SV=2 8.75 3898.4 - 2.79E+06 - - - -1.3836 - 2.285 0.499 - 545.7 1 1 0 -0.0022 15 0 0 0 1.83E+07 1.34E+07 - - - 4.7576 1 221125_WJC_METTL3_EV_vs_WT_F02.24195.24195.3 2.04E-05 16/52 R.DALPELLGLEAGSR[166.11].R "sp|Q9NSI2|SLX9_HUMAN,tr|C9JJU7|C9JJU7_HUMAN" 2 1449.7703 1.99 22844 24195 3 1449.770725 484.264 Ribosome biogenesis protein SLX9 homolog OS=Homo sapiens OX=9606 GN=SLX9 PE=1 SV=2 4.14 3898.6 - 2.30E+06 - - - 0.3076 - 2.772 0.477 - 347.9 1 2 0 0.0004 14 0 0 0 1.43E+07 7.17E+06 - - - 6.5675 1 221125_WJC_METTL3_EV_vs_WT_F02.24196.24196.3 1.46E-10 16/64 R.DLNC[160.03]VPEIADTLGAVAK.Q "sp|O14744|ANM5_HUMAN,tr|C9JSX3|C9JSX3_HUMAN,tr|G3V580|G3V580_HUMAN,tr|G3V2L6|G3V2L6_HUMAN,tr|G3V2F5|G3V2F5_HUMAN,tr|G3V2X6|G3V2X6_HUMAN,tr|G3V507|G3V507_HUMAN" 7 1784.8979 3.6 22845 24196 3 1784.899098 595.9732 Protein arginine N-methyltransferase 5 OS=Homo sapiens OX=9606 GN=PRMT5 PE=1 SV=4 4.03 3898.7 - 2.20E+06 - - - 0.6992 - 3.15 0.643 - 359.7 1 2 0 0.0012 17 0 0 0 3.73E+07 1.04E+07 - - - 8.6072 1 221125_WJC_METTL3_EV_vs_WT_F02.24198.24198.2 1.76E-09 16/40 R.IPLNPYLNLHSLLPASNLAGK.E "tr|E9PAU2|E9PAU2_HUMAN,tr|A0A087WZ13|A0A087WZ13_HUMAN" 2 2244.263 -1 22847 24198 2 2244.264777 1123.1388 Ribonucleoprotein PTB-binding 1 OS=Homo sapiens OX=9606 GN=RAVER1 PE=1 SV=1 8.6 3898.9 - 1.24E+06 - - - 0.7744 - 3.496 0.712 - 425.6 1 2 0 0.0017 21 0 0 0 0.00E+00 0.00E+00 - - - 7.3764 1 221125_WJC_METTL3_EV_vs_WT_F02.24199.24199.2 6.08E-19 24/44 K.GIGMGNIGPAGMGMEGIGFGINK.M "sp|P52272|HNRPM_HUMAN,tr|M0QYL3|M0QYL3_HUMAN,tr|A0A087X0X3|A0A087X0X3_HUMAN,tr|M0QZM1|M0QZM1_HUMAN" 4 2177.0432 1.19 22848 24199 2 2177.039587 1089.5289 Heterogeneous nuclear ribonucleoprotein M OS=Homo sapiens OX=9606 GN=HNRNPM PE=1 SV=3 6 3899.1 - 1.22E+06 - - - -1.6371 - 4.169 0.737 - 1517.8 1 2 0 -0.0036 23 0 0 0 8.75E+06 7.37E+06 - - - 7.9934 1 221125_WJC_METTL3_EV_vs_WT_F02.24201.24201.3 2.36E-07 14/56 R.K[136.11]IPNPDFFEDLEPFR[166.11].M "sp|P27824|CALX_HUMAN,tr|A0A7P0T937|A0A7P0T937_HUMAN,tr|A0A7P0T840|A0A7P0T840_HUMAN,tr|A0A7P0TB65|A0A7P0TB65_HUMAN,tr|A0A7P0TAE9|A0A7P0TAE9_HUMAN,tr|D6RGY2|D6RGY2_HUMAN,tr|A0A7P0T8G1|A0A7P0T8G1_HUMAN,tr|A0A7P0Z4D6|A0A7P0Z4D6_HUMAN,tr|A0A7P0T9L0|A0A7P0T9L0_HUMAN" 9 1880.9428 1.03 22850 24201 3 1880.9469 627.9882 Calnexin OS=Homo sapiens OX=9606 GN=CANX PE=1 SV=2 4.32 3899.3 - 1.11E+06 - - - 2.1957 - 2.732 0.517 - 259.7 1 2 0 0.0041 15 0 0 0 1.43E+07 1.39E+07 - - - 6.9254 1 221125_WJC_METTL3_EV_vs_WT_F02.24203.24203.2 8.72E-10 Dec-46 R.SYLAPGLLQGQVAIVTGGATGIGK.A "sp|Q9BY49|PECR_HUMAN,tr|B4DJS2|B4DJS2_HUMAN" 2 2270.2634 -1 22852 24203 2 2270.262265 1136.139 Peroxisomal trans-2-enoyl-CoA reductase OS=Homo sapiens OX=9606 GN=PECR PE=1 SV=2 8.31 3899.6 - 990646 - - - -0.5145 - 2.679 0.722 - 298.5 1 2 0 -0.0012 24 0 0 0 0.00E+00 0.00E+00 - - - 6.7961 1 221125_WJC_METTL3_EV_vs_WT_F02.24204.24204.2 3.83E-14 19/36 R.ILQEAQNLMALTNVDTPLK.G sp|Q99459|CDC5L_HUMAN 1 2111.1296 -1 22853 24204 2 2111.129761 1056.5721 Cell division cycle 5-like protein OS=Homo sapiens OX=9606 GN=CDC5L PE=1 SV=2 4.37 3899.7 - 977734 - - - 0.0568 - 4.161 0.71 - 1202.4 1 2 0 0.0001 19 0 0 0 0.00E+00 0.00E+00 - - - 7.7903 1 221125_WJC_METTL3_EV_vs_WT_F02.24206.24206.2 5.47E-13 23/44 K.LDIISPQLSSASLLTPQSAEC[160.03]LR.A "sp|Q15643|TRIPB_HUMAN,tr|H0YJ97|H0YJ97_HUMAN" 2 2498.305 -1 22855 24206 2 2498.307537 1250.1598 Thyroid receptor-interacting protein 11 OS=Homo sapiens OX=9606 GN=TRIP11 PE=1 SV=3 4.37 3900 - 878198 - - - 0.9995 - 4.447 0.732 - 1019.2 1 2 0 0.0025 23 0 0 0 0.00E+00 0.00E+00 - - - 8.1155 0.7871 221125_WJC_METTL3_EV_vs_WT_F02.24208.24208.2 0.128 Aug-34 C.VAVALSLIALLIGIC[160.03]GMK[136.11].Q sp|P56750|CLD17_HUMAN 1 1849.1024 4.81 22856 24208 2 1849.100873 925.5585 Claudin-17 OS=Homo sapiens OX=9606 GN=CLDN17 PE=1 SV=1 8.19 3900.2 - 1.10E+06 - - - -0.8442 - 1.361 0.199 - 72.5 1 1 0 -0.0016 18 0 0 0 1.19E+08 2.48E+07 - - - 1.2681 0.9956 221125_WJC_METTL3_EV_vs_WT_F02.24209.24209.2 0.0329 Apr-46 R.SYLAPGLLQGQVAIVTGGATGIGK[136.11].A "sp|Q9BY49|PECR_HUMAN,tr|B4DJS2|B4DJS2_HUMAN" 2 2278.2776 -1 22857 24209 2 2278.278072 1140.1461 Peroxisomal trans-2-enoyl-CoA reductase OS=Homo sapiens OX=9606 GN=PECR PE=1 SV=2 8.31 3900.3 - 0 - - - 0.1927 - 0.908 0.343 - 8.6 2 2 0 0.0004 24 0 0 0 0.00E+00 0.00E+00 - - - 1.2025 0.9676 221125_WJC_METTL3_EV_vs_WT_F02.24210.24210.2 1.57 18-Jun K.TVEDLELNIK.Y "sp|O15296|LX15B_HUMAN,tr|I3L1D5|I3L1D5_HUMAN" 2 1172.6289 999 22858 24210 2 1172.629708 587.3217 Polyunsaturated fatty acid lipoxygenase ALOX15B OS=Homo sapiens OX=9606 GN=ALOX15B PE=1 SV=3 4.14 3900.4 - 7.36E+06 - - - 0.7155 - 1.127 0.077 - 91.7 1 2 0 0.0008 10 0 0 0 4.30E+07 0.00E+00 - - - -0.0568 0.9999 221125_WJC_METTL3_EV_vs_WT_F02.24211.24211.2 0.000147 13/24 R.NLATTVTEEILEK[136.11].S "sp|O43390|HNRPR_HUMAN,tr|B4DT28|B4DT28_HUMAN,tr|A0A6Q8PHG0|A0A6Q8PHG0_HUMAN,tr|A0A6Q8PH31|A0A6Q8PH31_HUMAN,tr|A0A6Q8PH35|A0A6Q8PH35_HUMAN" 5 1467.7912 1.42 22859 24211 2 1467.791047 734.9029 Heterogeneous nuclear ribonucleoprotein R OS=Homo sapiens OX=9606 GN=HNRNPR PE=1 SV=1 4.25 3900.4 - 4.38E+06 - - - -0.0974 - 2.495 0.487 - 451.1 1 2 0 -0.0001 13 0 0 0 9.33E+07 6.59E+07 - - - 4.9845 0.9995 221125_WJC_METTL3_EV_vs_WT_F02.24215.24215.3 0.000531 Oct-48 R.NLATTVTEEILEK.S "sp|O43390|HNRPR_HUMAN,tr|B4DT28|B4DT28_HUMAN,tr|A0A6Q8PHG0|A0A6Q8PHG0_HUMAN,tr|A0A6Q8PH31|A0A6Q8PH31_HUMAN,tr|A0A6Q8PH35|A0A6Q8PH35_HUMAN" 5 1459.777 1.42 22863 24215 3 1459.776543 487.5996 Heterogeneous nuclear ribonucleoprotein R OS=Homo sapiens OX=9606 GN=HNRNPR PE=1 SV=1 4.25 3900.6 - 1.85E+06 - - - -0.3062 - 2.065 0.302 - 211.7 1 2 0 -0.0004 13 0 0 0 1.97E+07 1.38E+07 - - - 3.8729 0.9873 221125_WJC_METTL3_EV_vs_WT_F02.24216.24216.2 1.83E-05 24-Jul K.EKPYFPIPEEYTF.L "sp|Q00839|HNRPU_HUMAN,tr|A0A1W2PQL0|A0A1W2PQL0_HUMAN,tr|A0A1W2PPL4|A0A1W2PPL4_HUMAN,tr|A0A1W2PQ74|A0A1W2PQ74_HUMAN,tr|Q5RI18|Q5RI18_HUMAN,tr|A0A1W2PP35|A0A1W2PP35_HUMAN,tr|A0A1W2PPS1|A0A1W2PPS1_HUMAN,tr|A0A1W2PRZ7|A0A1W2PRZ7_HUMAN,tr|A0A1W2PPH7|A0A1W2PPH7_HUMAN,tr|A0A1W2PP34|A0A1W2PP34_HUMAN,tr|A0A1X7SBS1|A0A1X7SBS1_HUMAN" 11 1658.7868 2.7 22864 24216 2 1658.787004 830.4007 Heterogeneous nuclear ribonucleoprotein U OS=Homo sapiens OX=9606 GN=HNRNPU PE=1 SV=6 4.25 3900.7 - 1.19E+06 - - - 0.1073 - 1.745 0.477 - 109.3 1 1 0 0.0002 13 0 0 0 5.98E+06 2.22E+06 - - - 3.993 0.9951 221125_WJC_METTL3_EV_vs_WT_F02.24217.24217.3 7.51E-07 15/64 N.QSLLTPLNLQIDPAIQR.V "sp|P48668|K2C6C_HUMAN,sp|P04259|K2C6B_HUMAN" 2 1919.084 999 22865 24217 3 1919.087596 640.7019 "Keratin, type II cytoskeletal 6C OS=Homo sapiens OX=9606 GN=KRT6C PE=1 SV=3" 5.84 3900.7 - 1.11E+06 - - - 1.8681 - 2.775 0.498 - 167.1 1 1 0 0.0036 17 0 0 0 1.61E+07 0.00E+00 - - - 6.6697 1 221125_WJC_METTL3_EV_vs_WT_F02.24218.24218.2 1.77E-09 21/44 K.GIGMGNIGPAGMGMEGIGFGINK[136.11].M "sp|P52272|HNRPM_HUMAN,tr|M0QYL3|M0QYL3_HUMAN,tr|A0A087X0X3|A0A087X0X3_HUMAN,tr|M0QZM1|M0QZM1_HUMAN" 4 2185.0574 1.19 22866 24218 2 2185.059033 1093.536 Heterogeneous nuclear ribonucleoprotein M OS=Homo sapiens OX=9606 GN=HNRNPM PE=1 SV=3 6 3900.9 - 904638 - - - 0.7698 - 4.021 0.722 - 1147.1 1 2 0 0.0017 23 0 0 0 8.75E+06 7.37E+06 - - - 7.7943 0.9998 221125_WJC_METTL3_EV_vs_WT_F02.24219.24219.2 0.00406 14/28 K.AVASLPPEQMFELMK.Q "sp|P33240|CSTF2_HUMAN,sp|Q9H0L4|CSTFT_HUMAN,tr|A0A0A0MT56|A0A0A0MT56_HUMAN,tr|E9PID8|E9PID8_HUMAN,tr|E7EWR4|E7EWR4_HUMAN" 5 1689.847 3.47 22867 24219 2 1689.848808 845.9308 Cleavage stimulation factor subunit 2 OS=Homo sapiens OX=9606 GN=CSTF2 PE=1 SV=1 4.53 3901 - 870936 - - - 1.0693 - 2.362 0.472 - 453.2 1 2 0 0.0018 15 0 0 0 1.17E+07 3.39E+06 - - - 4.6398 0.9999 221125_WJC_METTL3_EV_vs_WT_F02.24221.24221.3 0.000116 Dec-52 K.TALALAIAQELGSK[136.11].V "sp|Q9Y265|RUVB1_HUMAN,tr|E7ETR0|E7ETR0_HUMAN" 2 1392.8068 0.79 22869 24221 3 1392.806823 465.2762 RuvB-like 1 OS=Homo sapiens OX=9606 GN=RUVBL1 PE=1 SV=1 5.66 3901.3 - 582600 - - - 0.0309 - 2.716 0.42 - 307.7 1 2 0 0 14 0 0 0 1.99E+06 2.53E+06 - - - 5.8779 1 221125_WJC_METTL3_EV_vs_WT_F02.24229.24229.2 3.31E-09 14/36 R.ILQEAQNLMALTNVDTPLK[136.11].G sp|Q99459|CDC5L_HUMAN 1 2119.1438 -1 22876 24229 2 2119.143612 1060.5792 Cell division cycle 5-like protein OS=Homo sapiens OX=9606 GN=CDC5L PE=1 SV=2 4.37 3902.3 - 277279 - - - -0.1081 - 3.405 0.671 - 544.3 1 2 0 -0.0002 19 0 0 0 0.00E+00 0.00E+00 - - - 7.0093 0.9999 221125_WJC_METTL3_EV_vs_WT_F02.24231.24231.2 3.16E-06 13/24 R.NLATTVTEEILEK.S "sp|O43390|HNRPR_HUMAN,tr|B4DT28|B4DT28_HUMAN,tr|A0A6Q8PHG0|A0A6Q8PHG0_HUMAN,tr|A0A6Q8PH31|A0A6Q8PH31_HUMAN,tr|A0A6Q8PH35|A0A6Q8PH35_HUMAN" 5 1459.777 1.42 22877 24231 2 1459.776503 730.8958 Heterogeneous nuclear ribonucleoprotein R OS=Homo sapiens OX=9606 GN=HNRNPR PE=1 SV=1 4.25 3902.5 - 8.08E+06 - - - -0.3336 - 2.78 0.49 - 461.9 1 2 0 -0.0005 13 0 0 0 9.33E+07 6.59E+07 - - - 5.2841 0.9999 221125_WJC_METTL3_EV_vs_WT_F02.24233.24233.3 0.0032 Dec-48 R.NLATTVTEEILEK[136.11].S "sp|O43390|HNRPR_HUMAN,tr|B4DT28|B4DT28_HUMAN,tr|A0A6Q8PHG0|A0A6Q8PHG0_HUMAN,tr|A0A6Q8PH31|A0A6Q8PH31_HUMAN,tr|A0A6Q8PH35|A0A6Q8PH35_HUMAN" 5 1467.7912 1.42 22879 24233 3 1467.792137 490.271 Heterogeneous nuclear ribonucleoprotein R OS=Homo sapiens OX=9606 GN=HNRNPR PE=1 SV=1 4.25 3902.6 - 1.21E+06 - - - 0.6452 - 2.399 0.375 - 283.5 1 2 0 0.0009 13 0 0 0 1.97E+07 1.38E+07 - - - 5.0931 0.9997 221125_WJC_METTL3_EV_vs_WT_F02.24234.24234.2 0.000143 14-Aug R.GFGFVLFK.E "sp|Q14103|HNRPD_HUMAN,sp|O14979|HNRDL_HUMAN,tr|H0Y8G5|H0Y8G5_HUMAN,tr|A0A087WUK2|A0A087WUK2_HUMAN,tr|D6RF44|D6RF44_HUMAN,tr|D6RBQ9|D6RBQ9_HUMAN,tr|D6RAF8|D6RAF8_HUMAN,tr|H0YA96|H0YA96_HUMAN" 8 913.5062 1.33 22880 24234 2 913.505922 457.7604 Heterogeneous nuclear ribonucleoprotein D0 OS=Homo sapiens OX=9606 GN=HNRNPD PE=1 SV=1 8.75 3902.8 - 686750 - - - -0.277 - 1.504 0.468 - 207.8 1 2 0 -0.0003 8 0 0 0 4.32E+06 3.25E+06 - - - 3.7285 1 221125_WJC_METTL3_EV_vs_WT_F02.24235.24235.3 1.56E-07 22/68 K.YGLLQVSEGLSFLHSSVK[136.11].M "sp|Q6P3W7|SCYL2_HUMAN,tr|F8VSC5|F8VSC5_HUMAN,tr|A0A0U1RQQ9|A0A0U1RQQ9_HUMAN" 3 1971.0557 1.35 22881 24235 3 1971.053562 658.0258 SCY1-like protein 2 OS=Homo sapiens OX=9606 GN=SCYL2 PE=1 SV=1 6.75 3902.9 - 657015 - - - -1.0735 - 3.83 0.544 - 662.3 1 2 0 -0.0021 18 0 0 0 1.85E+07 1.37E+07 - - - 7.9483 1 221125_WJC_METTL3_EV_vs_WT_F02.24236.24236.2 3.67E-07 13/20 K.EAVGDLLDAFK[136.11].E "sp|Q04637|IF4G1_HUMAN,tr|C9J2Z7|C9J2Z7_HUMAN,tr|E7EUU4|E7EUU4_HUMAN,tr|E9PGM1|E9PGM1_HUMAN,tr|C9J6B6|C9J6B6_HUMAN,tr|E7EX73|E7EX73_HUMAN,tr|C9K073|C9K073_HUMAN,tr|A0A7I2Y1C3|A0A7I2Y1C3_HUMAN,tr|C9JF13|C9JF13_HUMAN,tr|A0A6Q8PFB2|A0A6Q8PFB2_HUMAN" 10 1184.6169 0.83 22882 24236 2 1184.61538 593.3157 Eukaryotic translation initiation factor 4 gamma 1 OS=Homo sapiens OX=9606 GN=EIF4G1 PE=1 SV=4 4.03 3903 - 496364 - - - -1.2443 - 2.741 0.572 - 624.6 1 2 0 -0.0015 11 0 0 0 9.60E+06 1.16E+07 - - - 5.9931 0.9994 221125_WJC_METTL3_EV_vs_WT_F02.24237.24237.2 9.63E-06 14/26 K.TALALAIAQELGSK[136.11].V "sp|Q9Y265|RUVB1_HUMAN,tr|E7ETR0|E7ETR0_HUMAN" 2 1392.8068 0.76 22883 24237 2 1392.811769 697.4107 RuvB-like 1 OS=Homo sapiens OX=9606 GN=RUVBL1 PE=1 SV=1 5.66 3903.1 - 396836 - - - 3.582 - 3.352 0.469 - 752 1 2 0 0.005 14 0 0 0 3.64E+06 4.77E+06 - - - 5.5388 0.9996 221125_WJC_METTL3_EV_vs_WT_F02.24238.24238.2 8.32E-08 15/36 K.GDITPLMAASSGGYLDIVK.L "sp|Q8IWZ3|ANKH1_HUMAN,tr|E9PDP5|E9PDP5_HUMAN,tr|D6RHC4|D6RHC4_HUMAN" 3 1906.971 1.93 22884 24238 2 1906.97606 954.4928 Ankyrin repeat and KH domain-containing protein 1 OS=Homo sapiens OX=9606 GN=ANKHD1 PE=1 SV=1 4.21 3903.3 - 374907 - - - 2.6456 - 3.338 0.431 - 607.7 1 2 0 0.005 19 0 0 0 3.49E+06 1.81E+06 - - - 5.1862 0.9999 221125_WJC_METTL3_EV_vs_WT_F02.24243.24243.2 7.98E-06 13/26 R.LAALADQWQFLVQK[136.11].S "sp|Q13813|SPTN1_HUMAN,tr|A0A0D9SF54|A0A0D9SF54_HUMAN,tr|A0A0D9SGF6|A0A0D9SGF6_HUMAN" 3 1637.9021 1.29 22889 24243 2 1637.900615 819.9583 "Spectrin alpha chain, non-erythrocytic 1 OS=Homo sapiens OX=9606 GN=SPTAN1 PE=1 SV=3" 5.84 3903.9 - 293099 - - - -0.8932 - 2.441 0.503 - 437 1 2 0 -0.0015 14 0 0 0 4.39E+06 3.41E+06 - - - 4.9952 0.9986 221125_WJC_METTL3_EV_vs_WT_F02.24244.24244.3 2.22E-08 13/56 R.AHMGMFTELAILYSK[136.11].F "sp|Q00610|CLH1_HUMAN,sp|P53675|CLH2_HUMAN,tr|J3KS13|J3KS13_HUMAN,tr|A0A087WV74|A0A087WV74_HUMAN,tr|A0A087WXH4|A0A087WXH4_HUMAN,tr|A0A087WVQ6|A0A087WVQ6_HUMAN" 6 1718.8615 0.22 22890 24244 3 1718.867354 573.9611 Clathrin heavy chain 1 OS=Homo sapiens OX=9606 GN=CLTC PE=1 SV=5 6.79 3904 - 290222 - - - 3.3854 - 2.654 0.289 - 213.5 1 2 0 0.0058 15 0 0 0 1.50E+06 6.85E+06 - - - 4.3074 0.9999 221125_WJC_METTL3_EV_vs_WT_F02.24247.24247.2 0.022 14/30 K.EELIAELQDC[160.03]EGLIVR.S "sp|O43175|SERA_HUMAN,tr|A0A2C9F2M7|A0A2C9F2M7_HUMAN,tr|A0A286YFB2|A0A286YFB2_HUMAN,tr|A0A286YF34|A0A286YF34_HUMAN,tr|A0A286YFC8|A0A286YFC8_HUMAN,tr|A0A286YF22|A0A286YF22_HUMAN,tr|A0A286YFL2|A0A286YFL2_HUMAN,tr|A0A286YFA2|A0A286YFA2_HUMAN,tr|A0A286YFM8|A0A286YFM8_HUMAN,tr|A0A286YER3|A0A286YER3_HUMAN" 10 1885.9455 1.98 22893 24247 2 1885.942869 943.98 D-3-phosphoglycerate dehydrogenase OS=Homo sapiens OX=9606 GN=PHGDH PE=1 SV=4 3.91 3904.4 - 80538.1 - - - -1.4104 - 2.979 0.52 - 700.3 1 2 0 -0.0027 16 0 0 0 1.48E+06 7.49E+05 - - - 5.5646 1 221125_WJC_METTL3_EV_vs_WT_F02.24249.24249.3 1.35E-10 14/56 R.KIPNPDFFEDLEPFR.M "sp|P27824|CALX_HUMAN,tr|A0A7P0T937|A0A7P0T937_HUMAN,tr|A0A7P0T840|A0A7P0T840_HUMAN,tr|A0A7P0TB65|A0A7P0TB65_HUMAN,tr|A0A7P0TAE9|A0A7P0TAE9_HUMAN,tr|D6RGY2|D6RGY2_HUMAN,tr|A0A7P0T8G1|A0A7P0T8G1_HUMAN,tr|A0A7P0Z4D6|A0A7P0Z4D6_HUMAN,tr|A0A7P0T9L0|A0A7P0T9L0_HUMAN" 9 1862.9203 1.42 22894 24249 3 1862.921378 621.9807 Calnexin OS=Homo sapiens OX=9606 GN=CANX PE=1 SV=2 4.32 3904.7 - 2.78E+06 - - - 0.5787 - 2.936 0.563 - 227.4 1 2 0 0.0011 15 0 0 0 1.77E+07 1.25E+07 - - - 7.627 1 221125_WJC_METTL3_EV_vs_WT_F02.24251.24251.3 1.04E-10 31/68 K.YGLLQVSEGLSFLHSSVK.M "sp|Q6P3W7|SCYL2_HUMAN,tr|F8VSC5|F8VSC5_HUMAN,tr|A0A0U1RQQ9|A0A0U1RQQ9_HUMAN" 3 1963.0415 1.35 22895 24251 3 1963.044586 655.3544 SCY1-like protein 2 OS=Homo sapiens OX=9606 GN=SCYL2 PE=1 SV=1 6.75 3904.9 - 6.35E+06 - - - 1.5833 - 4.206 0.642 - 1491 1 2 0 0.0031 18 0 0 0 1.85E+07 1.37E+07 - - - 9.2739 0.9999 221125_WJC_METTL3_EV_vs_WT_F02.24252.24252.2 4.10E-07 22-Dec K.TSFFQALGITTK[136.11].L "sp|Q8NHW5|RLA0L_HUMAN,sp|P05388|RLA0_HUMAN,tr|G3V210|G3V210_HUMAN,tr|F8VU65|F8VU65_HUMAN,tr|F8VWS0|F8VWS0_HUMAN,tr|F8VW21|F8VW21_HUMAN,tr|F8VPE8|F8VPE8_HUMAN" 7 1320.7169 1.11 22896 24252 2 1320.718411 661.3657 60S acidic ribosomal protein P0-like OS=Homo sapiens OX=9606 GN=RPLP0P6 PE=5 SV=1 8.41 3904.9 - 5.57E+06 - - - 1.1418 - 2.292 0.604 - 353.8 1 2 0 0.0015 12 0 0 0 9.33E+07 8.41E+07 - - - 5.684 1 221125_WJC_METTL3_EV_vs_WT_F02.24253.24253.2 6.04E-08 14/22 K.TSFFQALGITTK[136.11].L "sp|Q8NHW5|RLA0L_HUMAN,sp|P05388|RLA0_HUMAN,tr|G3V210|G3V210_HUMAN,tr|F8VU65|F8VU65_HUMAN,tr|F8VWS0|F8VWS0_HUMAN,tr|F8VW21|F8VW21_HUMAN,tr|F8VPE8|F8VPE8_HUMAN" 7 1320.7169 1.11 22897 24253 2 1320.71776 661.3657 60S acidic ribosomal protein P0-like OS=Homo sapiens OX=9606 GN=RPLP0P6 PE=5 SV=1 8.41 3905 - 5.57E+06 - - - 0.6489 - 2.424 0.617 - 473.1 1 2 0 0.0009 12 0 0 0 9.33E+07 8.41E+07 - - - 5.9276 1 221125_WJC_METTL3_EV_vs_WT_F02.24255.24255.2 1.08E-10 19/32 K.GFFDPNTEENLTYLQLK.E sp|P15924|DESP_HUMAN 1 2027.984 29.11 22899 24255 2 2027.986578 1014.9993 Desmoplakin OS=Homo sapiens OX=9606 GN=DSP PE=1 SV=3 4.14 3905.2 - 2.05E+06 - - - 1.2599 - 3.409 0.699 - 961.4 1 2 0 0.0026 17 0 0 0 2.25E+07 7.71E+05 - - - 7.2182 1 221125_WJC_METTL3_EV_vs_WT_F02.24257.24257.2 1.50E-17 18/36 R.FADDTYTESYISTIGVDFK.L "sp|Q9H0U4|RAB1B_HUMAN,sp|P62820|RAB1A_HUMAN,tr|E9PLD0|E9PLD0_HUMAN" 3 2170.9946 1.74 22901 24257 2 2170.992547 1086.5046 Ras-related protein Rab-1B OS=Homo sapiens OX=9606 GN=RAB1B PE=1 SV=1 3.84 3905.4 - 1.69E+06 - - - -0.9673 - 3.553 0.684 - 984.9 1 2 0 -0.0021 19 0 0 0 1.05E+07 6.04E+06 - - - 7.2093 1 221125_WJC_METTL3_EV_vs_WT_F02.24258.24258.2 1.64E-07 15/24 R.QTFSPFGQIMEIR.V "sp|Q01085|TIAR_HUMAN,sp|P31483|TIA1_HUMAN,tr|F8W8I6|F8W8I6_HUMAN,tr|C9JTN7|C9JTN7_HUMAN,tr|F8WE16|F8WE16_HUMAN" 5 1552.7708 1.48 22902 24258 2 1552.770853 777.3927 Nucleolysin TIAR OS=Homo sapiens OX=9606 GN=TIAL1 PE=1 SV=1 6 3905.5 - 1.69E+06 - - - 0.0348 - 2.776 0.59 - 714 1 2 0 0.0001 13 0 0 0 2.74E+07 1.84E+07 - - - 6.0192 1 221125_WJC_METTL3_EV_vs_WT_F02.24259.24259.3 9.74E-07 22/80 K.ELGGLGMLSMGHVLIPQSDLR[166.11].W "sp|Q6P2Q9|PRP8_HUMAN,tr|I3L3Z8|I3L3Z8_HUMAN" 2 2232.1634 -1 22903 24259 3 2232.170021 745.0617 Pre-mRNA-processing-splicing factor 8 OS=Homo sapiens OX=9606 GN=PRPF8 PE=1 SV=2 5.32 3905.6 - 1.23E+06 - - - 2.9599 - 3.511 0.565 - 435.4 1 2 0 0.0066 21 0 0 0 0.00E+00 0.00E+00 - - - 7.8483 0.9999 221125_WJC_METTL3_EV_vs_WT_F02.24260.24260.3 3.77E-09 21/76 R.YGLSAAAAAAAAAAAAVEQR.S sp|Q9H1B7|I2BPL_HUMAN 1 1802.9275 1.73 22904 24260 3 1802.935714 601.9831 Probable E3 ubiquitin-protein ligase IRF2BPL OS=Homo sapiens OX=9606 GN=IRF2BPL PE=1 SV=1 6 3905.7 - 950562 - - - 4.5498 - 4.636 0.548 - 700 1 2 0 0.0082 20 0 0 0 5.73E+06 3.32E+06 - - - 8.3685 1 221125_WJC_METTL3_EV_vs_WT_F02.24264.24264.3 3.90E-12 17/72 R.ILQEAQNLMALTNVDTPLK[136.11].G sp|Q99459|CDC5L_HUMAN 1 2119.1438 1.38 22908 24264 3 2119.14568 707.3886 Cell division cycle 5-like protein OS=Homo sapiens OX=9606 GN=CDC5L PE=1 SV=2 4.37 3906.2 - 657445 - - - 0.8678 - 3.638 0.568 - 378.5 1 2 0 0.0018 19 0 0 0 1.11E+07 8.04E+06 - - - 8.0449 0.9982 221125_WJC_METTL3_EV_vs_WT_F02.24265.24265.3 2.13E-05 14/68 K.EAQTSFLHLGYLPNQLFR[166.11].T "sp|Q92499|DDX1_HUMAN,tr|A0A7I2V2M5|A0A7I2V2M5_HUMAN,tr|A0A087X2G1|A0A087X2G1_HUMAN,tr|A0A7I2V430|A0A7I2V430_HUMAN,tr|A0A7I2V4F0|A0A7I2V4F0_HUMAN,tr|A0A087WZ71|A0A087WZ71_HUMAN,tr|A0A7I2YQ77|A0A7I2YQ77_HUMAN" 7 2143.109 0.81 22909 24265 3 2143.117895 715.3769 ATP-dependent RNA helicase DDX1 OS=Homo sapiens OX=9606 GN=DDX1 PE=1 SV=2 6.85 3906.4 - 523922 - - - 4.1533 - 2.931 0.298 - 155.6 1 2 0 0.0089 18 0 0 0 2.37E+06 2.92E+06 - - - 4.5377 0.9822 221125_WJC_METTL3_EV_vs_WT_F02.24269.24269.3 0.112 Aug-68 K.AFLSTHPNTETVFEAFLK.S sp|Q96S44|PRPK_HUMAN 1 2051.0364 0.72 22913 24269 3 2051.036871 684.6861 EKC\KEOPS complex subunit TP53RK OS=Homo sapiens OX=9606 GN=TP53RK PE=1 SV=2 5.4 3906.9 - 393912 - - - 0.2331 - 1.418 0.184 - 50.2 1 2 0 0.0005 18 0 0 0 1.07E+06 1.49E+06 - - - 1.4609 0.9815 221125_WJC_METTL3_EV_vs_WT_F02.24270.24270.2 2.64 14-May R.GFGFVLFK[136.11].E "sp|Q14103|HNRPD_HUMAN,sp|O14979|HNRDL_HUMAN,tr|H0Y8G5|H0Y8G5_HUMAN,tr|A0A087WUK2|A0A087WUK2_HUMAN,tr|D6RF44|D6RF44_HUMAN,tr|D6RBQ9|D6RBQ9_HUMAN,tr|D6RAF8|D6RAF8_HUMAN,tr|H0YA96|H0YA96_HUMAN" 8 921.5204 1.33 22914 24270 2 921.519874 461.7675 Heterogeneous nuclear ribonucleoprotein D0 OS=Homo sapiens OX=9606 GN=HNRNPD PE=1 SV=1 8.75 3907 - 360331 - - - -0.5437 - 0.849 0.228 - 70.5 1 2 0 -0.0005 8 0 0 0 4.32E+06 3.25E+06 - - - 0.2312 0.9644 221125_WJC_METTL3_EV_vs_WT_F02.24272.24272.2 2.05E-06 14/32 L.MTDETISNVPILILGNK[136.11].L "sp|Q9NR31|SAR1A_HUMAN,tr|H0Y5E8|H0Y5E8_HUMAN" 2 1865.006 1.66 22915 24272 2 1864.999599 933.5103 GTP-binding protein SAR1a OS=Homo sapiens OX=9606 GN=SAR1A PE=1 SV=1 4.37 3907.4 - 538239 - - - -3.4059 - 2.258 0.561 - 421.2 1 1 0 -0.0064 17 0 0 0 2.06E+06 1.24E+06 - - - 5.185 1 221125_WJC_METTL3_EV_vs_WT_F02.24276.24276.2 1.08E-07 14/24 R.DPENFPFVVLGNK.L "sp|P51149|RAB7A_HUMAN,tr|C9J592|C9J592_HUMAN,tr|A0A6Q8PH84|A0A6Q8PH84_HUMAN,tr|C9IZZ0|C9IZZ0_HUMAN,tr|A0A6Q8PGE6|A0A6Q8PGE6_HUMAN,tr|A0A6Q8PG52|A0A6Q8PG52_HUMAN" 6 1474.7456 1 22919 24276 2 1474.746239 738.3801 Ras-related protein Rab-7a OS=Homo sapiens OX=9606 GN=RAB7A PE=1 SV=1 4.37 3907.6 - 3.44E+06 - - - 0.413 - 3.063 0.67 - 854.2 1 2 0 0.0006 13 0 0 0 5.62E+07 5.63E+07 - - - 6.8624 1 221125_WJC_METTL3_EV_vs_WT_F02.24277.24277.3 2.06E-09 15/72 R.FADDTYTESYISTIGVDFK.L "sp|Q9H0U4|RAB1B_HUMAN,sp|P62820|RAB1A_HUMAN,tr|E9PLD0|E9PLD0_HUMAN" 3 2170.9946 2.81 22920 24277 3 2170.996363 724.6722 Ras-related protein Rab-1B OS=Homo sapiens OX=9606 GN=RAB1B PE=1 SV=1 3.84 3907.7 - 2.70E+06 - - - 0.7904 - 2.946 0.622 - 268.1 1 2 0 0.0017 19 0 0 0 1.33E+07 4.74E+06 - - - 8.1287 0.9999 221125_WJC_METTL3_EV_vs_WT_F02.24278.24278.2 1.07E-07 15/22 R.EEGWWVVIGDAK.S sp|O75643|U520_HUMAN 1 1387.6772 1.87 22921 24278 2 1387.677333 694.8459 U5 small nuclear ribonucleoprotein 200 kDa helicase OS=Homo sapiens OX=9606 GN=SNRNP200 PE=1 SV=2 4.14 3907.8 - 2.30E+06 - - - 0.0843 - 2.555 0.553 - 909.2 1 2 0 0.0001 12 0 0 0 1.29E+07 6.89E+06 - - - 5.5936 0.9999 221125_WJC_METTL3_EV_vs_WT_F02.24280.24280.2 2.88E-07 14/22 R.EEGWWVVIGDAK[136.11].S sp|O75643|U520_HUMAN 1 1395.6914 1.87 22923 24280 2 1395.691267 698.853 U5 small nuclear ribonucleoprotein 200 kDa helicase OS=Homo sapiens OX=9606 GN=SNRNP200 PE=1 SV=2 4.14 3907.9 - 1.24E+06 - - - -0.1068 - 2.384 0.49 - 759.7 1 2 0 -0.0001 12 0 0 0 1.29E+07 6.89E+06 - - - 4.946 0.9997 221125_WJC_METTL3_EV_vs_WT_F02.24283.24283.2 0.000491 13/26 R.LAALADQWQFLVQK.S "sp|Q13813|SPTN1_HUMAN,tr|A0A0D9SF54|A0A0D9SF54_HUMAN,tr|A0A0D9SGF6|A0A0D9SGF6_HUMAN" 3 1629.8879 1.29 22926 24283 2 1629.889429 815.9512 "Spectrin alpha chain, non-erythrocytic 1 OS=Homo sapiens OX=9606 GN=SPTAN1 PE=1 SV=3" 5.84 3908.2 - 932615 - - - 0.9516 - 2.571 0.352 - 418 1 2 0 0.0016 14 0 0 0 4.39E+06 3.41E+06 - - - 4.01 1 221125_WJC_METTL3_EV_vs_WT_F02.24286.24286.2 2.23E-07 14/26 R.C[160.03]GEEIAVQFVDMVK.G "sp|O43175|SERA_HUMAN,tr|A0A286YF78|A0A286YF78_HUMAN,tr|A0A2C9F2M7|A0A2C9F2M7_HUMAN,tr|A0A286YF22|A0A286YF22_HUMAN,tr|A0A286YFL2|A0A286YFL2_HUMAN,tr|A0A286YFA2|A0A286YFA2_HUMAN" 6 1623.7637 1.27 22929 24286 2 1623.769387 812.8891 D-3-phosphoglycerate dehydrogenase OS=Homo sapiens OX=9606 GN=PHGDH PE=1 SV=4 4.14 3908.6 - 702949 - - - 3.5239 - 3.13 0.569 - 772.5 1 2 0 0.0057 14 0 0 0 8.88E+06 6.98E+06 - - - 6.1052 1 221125_WJC_METTL3_EV_vs_WT_F02.24287.24287.3 8.29E-11 20/76 R.YGLSAAAAAAAAAAAAVEQR[166.11].S sp|Q9H1B7|I2BPL_HUMAN 1 1812.9358 1.73 22930 24287 3 1812.941138 605.3192 Probable E3 ubiquitin-protein ligase IRF2BPL OS=Homo sapiens OX=9606 GN=IRF2BPL PE=1 SV=1 6 3908.7 - 696585 - - - 2.9549 - 4.265 0.605 - 709.3 1 2 0 0.0054 20 0 0 0 5.73E+06 3.32E+06 - - - 8.8025 1 221125_WJC_METTL3_EV_vs_WT_F02.24288.24288.3 2.04E-12 24/76 R.TPLTQDPASITDNLLQLPAR.R sp|Q96DF8|ESS2_HUMAN 1 2163.1535 0.14 22931 24288 3 2163.151655 722.0585 Splicing factor ESS-2 homolog OS=Homo sapiens OX=9606 GN=ESS2 PE=1 SV=1 4.21 3908.8 - 642800 - - - -0.8751 - 4.174 0.579 - 631.5 1 2 0 -0.0019 20 0 0 0 4.41E+06 3.18E+07 - - - 8.4612 1 221125_WJC_METTL3_EV_vs_WT_F02.24289.24289.2 3.05E-08 18/36 K.IGVGAMTWSPLAC[160.03]GIVSGK.Y "sp|Q13303|KCAB2_HUMAN,tr|A0A590UJJ4|A0A590UJJ4_HUMAN,tr|A0A5F9UN28|A0A5F9UN28_HUMAN,tr|A0A590UJB6|A0A590UJB6_HUMAN" 4 1902.9696 -1 22932 24289 2 1902.969397 952.4921 Voltage-gated potassium channel subunit beta-2 OS=Homo sapiens OX=9606 GN=KCNAB2 PE=1 SV=2 8.22 3909 - 610055 - - - -0.0941 - 3.514 0.624 - 951.1 1 2 0 -0.0002 19 0 0 0 0.00E+00 0.00E+00 - - - 6.7396 0.9804 221125_WJC_METTL3_EV_vs_WT_F02.24290.24290.3 0.00529 Nov-76 R.LFPPWIKPADTEPPPLLVYK.W "sp|Q6P2Q9|PRP8_HUMAN,tr|I3L0J9|I3L0J9_HUMAN" 2 2320.2871 2.38 22933 24290 3 2320.289157 774.4363 Pre-mRNA-processing-splicing factor 8 OS=Homo sapiens OX=9606 GN=PRPF8 PE=1 SV=2 6.07 3909.1 - 606571 - - - 0.8745 - 1.863 0.124 - 101.1 1 2 0 0.002 20 0 0 0 2.71E+06 1.14E+06 - - - 1.4314 1 221125_WJC_METTL3_EV_vs_WT_F02.24291.24291.3 1.32E-08 16/48 R.QTFSPFGQIMEIR.V "sp|Q01085|TIAR_HUMAN,sp|P31483|TIA1_HUMAN,tr|F8W8I6|F8W8I6_HUMAN,tr|C9JTN7|C9JTN7_HUMAN,tr|F8WE16|F8WE16_HUMAN" 5 1552.7708 2.01 22934 24291 3 1552.769943 518.5975 Nucleolysin TIAR OS=Homo sapiens OX=9606 GN=TIAL1 PE=1 SV=1 6 3909.2 - 585807 - - - -0.5513 - 2.534 0.602 - 313.3 1 2 0 -0.0009 13 0 0 0 2.11E+06 1.05E+06 - - - 7.7724 0.9997 221125_WJC_METTL3_EV_vs_WT_F02.24294.24294.3 0.000229 Oct-48 R.LDLVHTAALMLDK.N "sp|O75643|U520_HUMAN,tr|A0A494C1A5|A0A494C1A5_HUMAN" 2 1438.7854 2.12 22936 24294 3 1438.784628 480.6024 U5 small nuclear ribonucleoprotein 200 kDa helicase OS=Homo sapiens OX=9606 GN=SNRNP200 PE=1 SV=2 5.21 3909.6 - 535849 - - - -0.5275 - 2.217 0.325 - 98.1 1 2 0 -0.0008 13 0 0 0 2.05E+06 9.70E+05 - - - 4.3218 1 221125_WJC_METTL3_EV_vs_WT_F02.24295.24295.3 1.29E-05 17/72 R.YVASYLLAALGGNSSPSAK.D sp|P05387|RLA2_HUMAN 1 1867.968 1.18 22937 24295 3 1867.967815 623.6633 60S acidic ribosomal protein P2 OS=Homo sapiens OX=9606 GN=RPLP2 PE=1 SV=1 8.5 3909.6 - 8.52E+06 - - - -0.0878 - 3.249 0.571 - 327.6 1 2 0 -0.0002 19 0 0 0 5.08E+07 4.31E+07 - - - 7.801 1 221125_WJC_METTL3_EV_vs_WT_F02.24296.24296.3 3.14E-06 14/72 R.YVASYLLAALGGNSSPSAK[136.11].D sp|P05387|RLA2_HUMAN 1 1875.9822 1.18 22938 24296 3 1875.982135 626.3347 60S acidic ribosomal protein P2 OS=Homo sapiens OX=9606 GN=RPLP2 PE=1 SV=1 8.5 3909.7 - 7.32E+06 - - - -0.0235 - 2.943 0.519 - 208.8 1 2 0 0 19 0 0 0 5.08E+07 4.31E+07 - - - 6.9783 1 221125_WJC_METTL3_EV_vs_WT_F02.24297.24297.3 6.33E-10 Oct-64 K.GFFDPNTEENLTYLQLK.E sp|P15924|DESP_HUMAN 1 2027.984 30.45 22939 24297 3 2027.983736 677.002 Desmoplakin OS=Homo sapiens OX=9606 GN=DSP PE=1 SV=3 4.14 3909.7 - 5.52E+06 - - - -0.1415 - 2.482 0.656 - 95.6 1 2 0 -0.0003 17 0 0 0 1.71E+07 5.62E+05 - - - 8.1502 1 221125_WJC_METTL3_EV_vs_WT_F02.24298.24298.2 3.25E-08 22/36 R.YVASYLLAALGGNSSPSAK.D sp|P05387|RLA2_HUMAN 1 1867.968 1.21 22940 24298 2 1867.96785 934.9913 60S acidic ribosomal protein P2 OS=Homo sapiens OX=9606 GN=RPLP2 PE=1 SV=1 8.5 3909.7 - 5.28E+06 - - - -0.0691 - 3.798 0.679 - 1433 1 2 0 -0.0001 19 0 0 0 4.06E+07 3.36E+07 - - - 7.3369 1 221125_WJC_METTL3_EV_vs_WT_F02.24299.24299.2 4.02E-05 22/36 R.YVASYLLAALGGNSSPSAK[136.11].D sp|P05387|RLA2_HUMAN 1 1875.9822 1.21 22941 24299 2 1875.982002 938.9984 60S acidic ribosomal protein P2 OS=Homo sapiens OX=9606 GN=RPLP2 PE=1 SV=1 8.5 3909.8 - 5.11E+06 - - - -0.0944 - 3.7 0.643 - 1249.3 1 2 0 -0.0002 19 0 0 0 4.06E+07 3.36E+07 - - - 7.0067 1 221125_WJC_METTL3_EV_vs_WT_F02.24301.24301.3 4.82E-12 23/72 K.GFFDPNTHENLTYLQLLER.C "sp|P58107|EPIPL_HUMAN,sp|P58107|EPIPL_HUMAN,sp|Q15149|PLEC_HUMAN,tr|A0A075B730|A0A075B730_HUMAN,tr|A0A075B730|A0A075B730_HUMAN,tr|H0YDN1|H0YDN1_HUMAN" 6 2306.1331 -1 22943 24301 3 2306.13503 769.7183 Epiplakin OS=Homo sapiens OX=9606 GN=EPPK1 PE=1 SV=3 4.65 3910 - 1.73E+06 - - - 0.8165 - 4.167 0.711 - 572 1 2 0 0.0019 19 0 0 0 0.00E+00 0.00E+00 - - - 9.9728 1 221125_WJC_METTL3_EV_vs_WT_F02.24302.24302.3 0.000102 13/52 K.LQDAYYIFQEMADK.C "sp|O14579|COPE_HUMAN,tr|M0QXB4|M0QXB4_HUMAN" 2 1733.7971 1.03 22944 24302 3 1733.798514 578.9396 Coatomer subunit epsilon OS=Homo sapiens OX=9606 GN=COPE PE=1 SV=3 4.03 3910.1 - 1.55E+06 - - - 0.8311 - 2.081 0.505 - 116.2 1 2 0 0.0014 14 0 0 0 3.28E+06 3.17E+06 - - - 6.1174 1 221125_WJC_METTL3_EV_vs_WT_F02.24303.24303.3 1.08E-05 20/72 K.LGGTIDDC[160.03]ELVEGLVLTQK[136.11].V sp|P50991|TCPD_HUMAN 1 2067.0649 0.41 22945 24303 3 2067.068492 690.0289 T-complex protein 1 subunit delta OS=Homo sapiens OX=9606 GN=CCT4 PE=1 SV=4 3.92 3910.2 - 1.53E+06 - - - 1.7271 - 3.558 0.57 - 576.2 1 2 0 0.0036 19 0 0 0 1.99E+07 4.90E+07 - - - 8.0121 0.9923 221125_WJC_METTL3_EV_vs_WT_F02.24307.24307.2 2.71E-07 15/32 K.ISSIQSIVPALEIANAH.R "sp|P10809|CH60_HUMAN,tr|A0A7I2V2X6|A0A7I2V2X6_HUMAN,tr|A0A7I2YQK6|A0A7I2YQK6_HUMAN,tr|A0A7I2V599|A0A7I2V599_HUMAN,tr|A0A7I2YQ71|A0A7I2YQ71_HUMAN,tr|A0A7I2V5M1|A0A7I2V5M1_HUMAN,tr|A0A7I2V5K3|A0A7I2V5K3_HUMAN,tr|A0A7I2V369|A0A7I2V369_HUMAN" 8 1761.9625 - 22949 24307 2 1761.960894 881.9885 "60 kDa heat shock protein, mitochondrial OS=Homo sapiens OX=9606 GN=HSPD1 PE=1 SV=2" 5.24 3910.6 - 1.13E+06 - - - -0.9109 - 2.854 0.456 - 539 1 1 0 -0.0016 17 0 0 0 - - - - - 4.9868 1 221125_WJC_METTL3_EV_vs_WT_F02.24308.24308.3 2.67E-05 13/72 K.IGVGAMTWSPLAC[160.03]GIVSGK.Y "sp|Q13303|KCAB2_HUMAN,tr|A0A590UJJ4|A0A590UJJ4_HUMAN,tr|A0A5F9UN28|A0A5F9UN28_HUMAN,tr|A0A590UJB6|A0A590UJB6_HUMAN" 4 1902.9696 1.59 22950 24308 3 1902.970861 635.3305 Voltage-gated potassium channel subunit beta-2 OS=Homo sapiens OX=9606 GN=KCNAB2 PE=1 SV=2 8.22 3910.7 - 973533 - - - 0.6753 - 2.473 0.482 - 153.8 1 2 0 0.0013 19 0 0 0 2.81E+06 1.76E+06 - - - 6.1379 1 221125_WJC_METTL3_EV_vs_WT_F02.24310.24310.2 2.13E-07 13/26 K.LQDAYYIFQEMADK[136.11].C "sp|O14579|COPE_HUMAN,tr|M0QXB4|M0QXB4_HUMAN" 2 1741.8113 -1 22952 24310 2 1741.81019 871.9129 Coatomer subunit epsilon OS=Homo sapiens OX=9606 GN=COPE PE=1 SV=3 4.03 3910.9 - 803328 - - - -0.6218 - 2.832 0.557 - 645 1 2 0 -0.0011 14 0 0 0 0.00E+00 0.00E+00 - - - 5.767 0.9994 221125_WJC_METTL3_EV_vs_WT_F02.24311.24311.3 3.58E-06 Dec-56 K.MGIGGLDK[136.11]EFSDIFR[166.11].R "sp|P46459|NSF_HUMAN,tr|I3L0N3|I3L0N3_HUMAN" 2 1701.8515 -1 22953 24311 3 1701.850888 568.2911 Vesicle-fusing ATPase OS=Homo sapiens OX=9606 GN=NSF PE=1 SV=3 4.56 3911.1 - 742673 - - - -0.3667 - 2.471 0.362 - 100.3 1 2 1 -0.0006 15 0 0 0 0.00E+00 0.00E+00 - - - 4.9363 0.9559 221125_WJC_METTL3_EV_vs_WT_F02.24315.24315.3 0.0112 Aug-44 K.TSFFQALGITTK[136.11].L "sp|Q8NHW5|RLA0L_HUMAN,sp|P05388|RLA0_HUMAN,tr|G3V210|G3V210_HUMAN,tr|F8VU65|F8VU65_HUMAN,tr|F8VWS0|F8VWS0_HUMAN,tr|F8VW21|F8VW21_HUMAN,tr|F8VPE8|F8VPE8_HUMAN" 7 1320.7169 0.92 22956 24315 3 1320.71462 441.2462 60S acidic ribosomal protein P0-like OS=Homo sapiens OX=9606 GN=RPLP0P6 PE=5 SV=1 8.41 3911.5 - 103568 - - - -1.7286 - 1.465 0.14 - 76.8 1 2 0 -0.0023 12 0 0 0 8.63E+05 9.35E+05 - - - 1.1587 1 221125_WJC_METTL3_EV_vs_WT_F02.24316.24316.2 2.29E-09 24-Dec R.DPENFPFVVLGNK[136.11].L "sp|P51149|RAB7A_HUMAN,tr|C9J592|C9J592_HUMAN,tr|A0A6Q8PH84|A0A6Q8PH84_HUMAN,tr|C9IZZ0|C9IZZ0_HUMAN,tr|A0A6Q8PGE6|A0A6Q8PGE6_HUMAN,tr|A0A6Q8PG52|A0A6Q8PG52_HUMAN" 6 1482.7598 1.09 22957 24316 2 1482.758748 742.3872 Ras-related protein Rab-7a OS=Homo sapiens OX=9606 GN=RAB7A PE=1 SV=1 4.37 3911.6 - 2.05E+06 - - - -0.7297 - 2.564 0.684 - 609.4 1 2 0 -0.0011 13 0 0 0 4.40E+07 4.03E+07 - - - 6.5092 1 221125_WJC_METTL3_EV_vs_WT_F02.24317.24317.2 3.66E-13 22/36 K.LGGTIDDC[160.03]ELVEGLVLTQK[136.11].V sp|P50991|TCPD_HUMAN 1 2067.0649 0.36 22958 24317 2 2067.066313 1034.5397 T-complex protein 1 subunit delta OS=Homo sapiens OX=9606 GN=CCT4 PE=1 SV=4 3.92 3911.7 - 1.97E+06 - - - 0.6729 - 4.351 0.731 - 1627.7 1 2 0 0.0014 19 0 0 0 7.63E+06 2.14E+07 - - - 8.0548 1 221125_WJC_METTL3_EV_vs_WT_F02.24318.24318.2 1.84E-08 14/30 K.EGLISQDGSSLEALLR.T "sp|Q92785|REQU_HUMAN,tr|J3KMZ8|J3KMZ8_HUMAN" 2 1686.8788 -1 22959 24318 2 1686.880546 844.4467 Zinc finger protein ubi-d4 OS=Homo sapiens OX=9606 GN=DPF2 PE=1 SV=2 4.14 3911.8 - 1.91E+06 - - - 1.0179 - 2.746 0.628 - 595 1 2 0 0.0017 16 0 0 0 0.00E+00 0.00E+00 - - - 6.1624 1 221125_WJC_METTL3_EV_vs_WT_F02.24320.24320.3 0.00011 20/72 K.LGGTIDDC[160.03]ELVEGLVLTQK.V sp|P50991|TCPD_HUMAN 1 2059.0507 0.38 22961 24320 3 2059.055246 687.3575 T-complex protein 1 subunit delta OS=Homo sapiens OX=9606 GN=CCT4 PE=1 SV=4 3.92 3911.9 - 1.55E+06 - - - 2.1971 - 3.349 0.593 - 619.3 1 2 0 0.0045 19 0 0 0 1.86E+07 4.85E+07 - - - 8.1196 1 221125_WJC_METTL3_EV_vs_WT_F02.24321.24321.2 3.59E-10 16/26 K.YSNFVSFPLYLNGR.R "sp|Q12931|TRAP1_HUMAN,tr|I3L0K7|I3L0K7_HUMAN,tr|I3L239|I3L239_HUMAN,tr|I3L2D5|I3L2D5_HUMAN" 4 1675.8358 2.82 22962 24321 2 1675.837576 838.9252 "Heat shock protein 75 kDa, mitochondrial OS=Homo sapiens OX=9606 GN=TRAP1 PE=1 SV=3" 8.59 3912 - 1.38E+06 - - - 1.0347 - 3.23 0.686 - 854.7 1 2 0 0.0017 14 0 0 0 1.44E+07 5.09E+06 - - - 7.0495 1 221125_WJC_METTL3_EV_vs_WT_F02.24322.24322.2 1.57E-10 15/30 K.EGLISQDGSSLEALLR[166.11].T "sp|Q92785|REQU_HUMAN,tr|J3KMZ8|J3KMZ8_HUMAN" 2 1696.8871 -1 22963 24322 2 1696.884465 849.4508 Zinc finger protein ubi-d4 OS=Homo sapiens OX=9606 GN=DPF2 PE=1 SV=2 4.14 3912.1 - 1.29E+06 - - - -1.5523 - 2.881 0.628 - 687.1 1 2 0 -0.0026 16 0 0 0 0.00E+00 0.00E+00 - - - 6.2801 1 221125_WJC_METTL3_EV_vs_WT_F02.24323.24323.3 9.55E-08 20/60 R.VVSVLTVLHQDWLNGK.E "sp|P01860|IGHG3_HUMAN,sp|P01861|IGHG4_HUMAN,sp|P01857|IGHG1_HUMAN,tr|A0A4W9A917|A0A4W9A917_HUMAN,tr|A0A286YES1|A0A286YES1_HUMAN,tr|A0A0A0MS08|A0A0A0MS08_HUMAN,tr|A0A286YFJ8|A0A286YFJ8_HUMAN" 7 1806.9992 -1 22964 24323 3 1807.002283 603.3403 Immunoglobulin heavy constant gamma 3 OS=Homo sapiens OX=9606 GN=IGHG3 PE=1 SV=2 6.71 3912.1 - 1.25E+06 - - - 1.6956 - 3.971 0.59 - 410.8 1 2 0 0.0031 16 0 0 0 0.00E+00 0.00E+00 - - - 8.6554 0.9965 221125_WJC_METTL3_EV_vs_WT_F02.24324.24324.3 7.69E-06 16/64 K.ISSIQSIVPALEIANAH.R "sp|P10809|CH60_HUMAN,tr|A0A7I2V2X6|A0A7I2V2X6_HUMAN,tr|A0A7I2YQK6|A0A7I2YQK6_HUMAN,tr|A0A7I2V599|A0A7I2V599_HUMAN,tr|A0A7I2YQ71|A0A7I2YQ71_HUMAN,tr|A0A7I2V5M1|A0A7I2V5M1_HUMAN,tr|A0A7I2V5K3|A0A7I2V5K3_HUMAN,tr|A0A7I2V369|A0A7I2V369_HUMAN" 8 1761.9625 - 22965 24324 3 1761.96515 588.3281 "60 kDa heat shock protein, mitochondrial OS=Homo sapiens OX=9606 GN=HSPD1 PE=1 SV=2" 5.24 3912.2 - 1.12E+06 - - - 1.5046 - 3.022 0.494 - 339.6 1 1 0 0.0027 17 0 0 0 - - - - - 6.8408 1 221125_WJC_METTL3_EV_vs_WT_F02.24326.24326.2 3.76E-11 22/36 K.LGGTIDDC[160.03]ELVEGLVLTQK.V sp|P50991|TCPD_HUMAN 1 2059.0507 -1 22967 24326 2 2059.052798 1030.5326 T-complex protein 1 subunit delta OS=Homo sapiens OX=9606 GN=CCT4 PE=1 SV=4 3.92 3912.4 - 936251 - - - 1.0082 - 4.403 0.714 - 1572.1 1 2 0 0.0021 19 0 0 0 0.00E+00 0.00E+00 - - - 7.9582 0.9999 221125_WJC_METTL3_EV_vs_WT_F02.24327.24327.3 0.000289 Oct-52 K.LQDAYYIFQEMADK[136.11].C "sp|O14579|COPE_HUMAN,tr|M0QXB4|M0QXB4_HUMAN" 2 1741.8113 -1 22968 24327 3 1741.809972 581.611 Coatomer subunit epsilon OS=Homo sapiens OX=9606 GN=COPE PE=1 SV=3 4.03 3912.6 - 890270 - - - -0.7469 - 2.232 0.41 - 91.9 1 2 0 -0.0013 14 0 0 0 0.00E+00 0.00E+00 - - - 5.2445 1 221125_WJC_METTL3_EV_vs_WT_F02.24328.24328.3 1.84E-10 26/72 R.FLEFQYLTGGLVDPEVHGR.L sp|P15924|DESP_HUMAN 1 2176.0953 3.07 22969 24328 3 2176.091295 726.3724 Desmoplakin OS=Homo sapiens OX=9606 GN=DSP PE=1 SV=3 4.65 3912.6 - 770046 - - - -1.8423 - 3.921 0.598 - 564.7 1 2 0 -0.004 19 0 0 0 6.22E+06 2.02E+06 - - - 8.5628 1 221125_WJC_METTL3_EV_vs_WT_F02.24329.24329.3 2.34E-08 25/72 K.APDELWNSLGPHPIPVIFK.Q "sp|Q9UBQ6|EXTL2_HUMAN,tr|C9IYF5|C9IYF5_HUMAN,tr|F5GZK1|F5GZK1_HUMAN,tr|C9JEG3|C9JEG3_HUMAN" 4 2129.131 -1 22970 24329 3 2129.133729 710.7176 Exostosin-like 2 OS=Homo sapiens OX=9606 GN=EXTL2 PE=1 SV=1 5.32 3912.8 - 768959 - - - 1.2996 - 3.403 0.603 - 559.9 1 2 0 0.0028 19 0 0 0 0.00E+00 0.00E+00 - - - 8.2708 0.9739 221125_WJC_METTL3_EV_vs_WT_F02.24330.24330.3 0.25 13/52 R.NLSTVMDEIHTVLK.K sp|Q8IX12|CCAR1_HUMAN 1 1598.8338 4.56 22971 24330 3 1598.833849 533.9519 Cell division cycle and apoptosis regulator protein 1 OS=Homo sapiens OX=9606 GN=CCAR1 PE=1 SV=2 5.32 3912.9 - 752123 - - - 0.035 - 1.813 0.1 - 126.5 1 2 0 0.0001 14 0 0 0 1.86E+06 4.07E+05 - - - 1.2361 0.9996 221125_WJC_METTL3_EV_vs_WT_F02.24331.24331.2 0.000284 14/26 K.LQDAYYIFQEMADK.C "sp|O14579|COPE_HUMAN,tr|M0QXB4|M0QXB4_HUMAN" 2 1733.7971 1.96 22972 24331 2 1733.800496 867.9058 Coatomer subunit epsilon OS=Homo sapiens OX=9606 GN=COPE PE=1 SV=3 4.03 3913 - 674475 - - - 1.9743 - 2.416 0.414 - 514.3 1 2 0 0.0034 14 0 0 0 3.07E+06 1.57E+06 - - - 4.3113 0.9905 221125_WJC_METTL3_EV_vs_WT_F02.24332.24332.2 1.26E-07 13/28 K.KISSIQSIVPALEIA.N "sp|P10809|CH60_HUMAN,tr|A0A7I2V2X6|A0A7I2V2X6_HUMAN,tr|A0A7I2YQK6|A0A7I2YQK6_HUMAN,tr|A0A7I2V599|A0A7I2V599_HUMAN,tr|A0A7I2YQ71|A0A7I2YQ71_HUMAN,tr|A0A7I2V5M1|A0A7I2V5M1_HUMAN,tr|A0A7I2V5K3|A0A7I2V5K3_HUMAN,tr|A0A7I2V369|A0A7I2V369_HUMAN" 8 1567.9185 1.35 22973 24332 2 1567.92027 784.9665 "60 kDa heat shock protein, mitochondrial OS=Homo sapiens OX=9606 GN=HSPD1 PE=1 SV=2" 6 3913.2 - 600043 - - - 1.1231 - 2.585 0.486 - 445.3 1 1 0 0.0018 15 0 0 0 1.42E+07 1.06E+07 - - - 4.965 1 221125_WJC_METTL3_EV_vs_WT_F02.24333.24333.3 4.86E-10 17/92 R.FPGSMEGFVTLDEVGDEEDSELQK.L tr|A8MXP9|A8MXP9_HUMAN 1 2657.1691 2.14 22974 24333 3 2657.169725 886.7303 Matrin-3 OS=Homo sapiens OX=9606 GN=MATR3 PE=1 SV=1 3.62 3913.3 - 562489 - - - 0.2506 - 3.256 0.56 - 274.9 1 2 0 0.0007 24 0 0 0 3.34E+06 1.56E+06 - - - 7.5251 0.9999 221125_WJC_METTL3_EV_vs_WT_F02.24335.24335.2 1.40E-08 13/26 R.C[160.03]GEEIAVQFVDMVK[136.11].G "sp|O43175|SERA_HUMAN,tr|A0A286YF78|A0A286YF78_HUMAN,tr|A0A2C9F2M7|A0A2C9F2M7_HUMAN,tr|A0A286YF22|A0A286YF22_HUMAN,tr|A0A286YFL2|A0A286YFL2_HUMAN,tr|A0A286YFA2|A0A286YFA2_HUMAN" 6 1631.7779 1.27 22975 24335 2 1631.778502 816.8962 D-3-phosphoglycerate dehydrogenase OS=Homo sapiens OX=9606 GN=PHGDH PE=1 SV=4 4.14 3913.5 - 546431 - - - 0.3904 - 2.423 0.564 - 605.5 1 2 0 0.0006 14 0 0 0 8.88E+06 6.98E+06 - - - 5.4274 1 221125_WJC_METTL3_EV_vs_WT_F02.24336.24336.3 1.33E-07 15/92 R.FPGSMEGFVTLDEVGDEEDSELQK[136.11].L tr|A8MXP9|A8MXP9_HUMAN 1 2665.1833 -1 22976 24336 3 2665.183223 889.4017 Matrin-3 OS=Homo sapiens OX=9606 GN=MATR3 PE=1 SV=1 3.62 3913.7 - 381919 - - - -0.0135 - 2.712 0.467 - 164.7 1 2 0 0 24 0 0 0 0.00E+00 0.00E+00 - - - 6.0638 1 221125_WJC_METTL3_EV_vs_WT_F02.24337.24337.3 3.64E-12 25/72 K.SDLEMQYETLQEELMALKK.N "sp|P35527|K1C9_HUMAN,tr|K7EQQ3|K7EQQ3_HUMAN" 2 2298.1123 81.98 22977 24337 3 2298.11352 767.0447 "Keratin, type I cytoskeletal 9 OS=Homo sapiens OX=9606 GN=KRT9 PE=1 SV=3" 4.25 3913.7 - 9.16E+06 - - - 0.5152 - 4.599 0.732 - 1159 1 2 0 0.0012 19 0 0 0 8.87E+07 1.08E+06 - - - 10.4494 1 221125_WJC_METTL3_EV_vs_WT_F02.24338.24338.2 1.07E-06 17/32 K.GTVLDQVPVNPSLYLIK.Y "sp|Q5JUX0|SPIN3_HUMAN,sp|Q9Y657|SPIN1_HUMAN" 2 1855.0455 2.41 22978 24338 2 1855.046611 928.53 Spindlin-3 OS=Homo sapiens OX=9606 GN=SPIN3 PE=1 SV=1 5.83 3913.8 - 4.01E+06 - - - 0.5984 - 3.226 0.594 - 562.2 1 2 0 0.0011 17 0 0 0 1.32E+07 5.50E+06 - - - 6.3075 1 221125_WJC_METTL3_EV_vs_WT_F02.24339.24339.3 6.60E-07 17/64 K.GTVLDQVPVNPSLYLIK.Y "sp|Q5JUX0|SPIN3_HUMAN,sp|Q9Y657|SPIN1_HUMAN" 2 1855.0455 2.21 22979 24339 3 1855.047994 619.3558 Spindlin-3 OS=Homo sapiens OX=9606 GN=SPIN3 PE=1 SV=1 5.83 3913.8 - 3.32E+06 - - - 1.3439 - 3.193 0.58 - 399.5 1 2 0 0.0025 17 0 0 0 1.06E+07 4.80E+06 - - - 7.9387 1 221125_WJC_METTL3_EV_vs_WT_F02.24341.24341.3 1.04E-06 24/80 K.TVLGTPEVLLGALPGAGGTQR.L "sp|P40939|ECHA_HUMAN,tr|A0A2R8YG21|A0A2R8YG21_HUMAN,tr|A0A2R8Y688|A0A2R8Y688_HUMAN,tr|H0YFD6|H0YFD6_HUMAN" 4 2006.116 0.76 22981 24341 3 2006.119943 669.7126 "Trifunctional enzyme subunit alpha, mitochondrial OS=Homo sapiens OX=9606 GN=HADHA PE=1 SV=2" 5.66 3914 - 1.79E+06 - - - 1.9456 - 3.74 0.568 - 420.6 1 2 0 0.0039 21 0 0 0 7.68E+06 1.01E+07 - - - 8.034 1 221125_WJC_METTL3_EV_vs_WT_F02.24342.24342.3 8.98E-09 26/80 K.TVLGTPEVLLGALPGAGGTQR[166.11].L "sp|P40939|ECHA_HUMAN,tr|A0A2R8YG21|A0A2R8YG21_HUMAN,tr|A0A2R8Y688|A0A2R8Y688_HUMAN,tr|H0YFD6|H0YFD6_HUMAN" 4 2016.1243 0.76 22982 24342 3 2016.12648 673.0487 "Trifunctional enzyme subunit alpha, mitochondrial OS=Homo sapiens OX=9606 GN=HADHA PE=1 SV=2" 5.66 3914.1 - 1.79E+06 - - - 1.0763 - 3.86 0.562 - 502.5 1 2 0 0.0022 21 0 0 0 7.68E+06 1.01E+07 - - - 8.0433 1 221125_WJC_METTL3_EV_vs_WT_F02.24345.24345.3 8.32E-07 Dec-52 K.YSNFVSFPLYLNGR.R "sp|Q12931|TRAP1_HUMAN,tr|I3L0K7|I3L0K7_HUMAN,tr|I3L239|I3L239_HUMAN,tr|I3L2D5|I3L2D5_HUMAN" 4 1675.8358 2.29 22985 24345 3 1675.836496 559.6192 "Heat shock protein 75 kDa, mitochondrial OS=Homo sapiens OX=9606 GN=TRAP1 PE=1 SV=3" 8.59 3914.3 - 1.53E+06 - - - 0.3903 - 2.126 0.512 - 153.1 1 2 0 0.0007 14 0 0 0 3.68E+06 1.61E+06 - - - 6.2525 1 221125_WJC_METTL3_EV_vs_WT_F02.24347.24347.3 8.04E-08 17/72 R.FLEFQYLTGGLVDPEVHGR[166.11].L sp|P15924|DESP_HUMAN 1 2186.1036 -1 22987 24347 3 2186.100679 729.7085 Desmoplakin OS=Homo sapiens OX=9606 GN=DSP PE=1 SV=3 4.65 3914.5 - 1.20E+06 - - - -1.3243 - 3.378 0.561 - 310.3 1 2 0 -0.0029 19 0 0 0 0.00E+00 0.00E+00 - - - 7.7844 0.9999 221125_WJC_METTL3_EV_vs_WT_F02.24348.24348.3 2.93E-07 13/84 R.GIFPVLC[160.03]KDPVQEAWAEDVDLR.V "sp|P14618|KPYM_HUMAN,tr|B4DNK4|B4DNK4_HUMAN,tr|A0A804F6T5|A0A804F6T5_HUMAN,tr|H3BR70|H3BR70_HUMAN,tr|A0A804F729|A0A804F729_HUMAN" 5 2556.2683 -1 22988 24348 3 2556.26923 853.0967 Pyruvate kinase PKM OS=Homo sapiens OX=9606 GN=PKM PE=1 SV=4 4.11 3914.6 - 1.04E+06 - - - 0.3795 - 2.888 0.525 - 134.2 1 2 1 0.001 22 0 0 0 0.00E+00 0.00E+00 - - - 6.9074 0.9995 221125_WJC_METTL3_EV_vs_WT_F02.24353.24353.2 0.000198 30-Dec R.EIMEILQTELGESAGK.L "sp|Q8IWJ2|GCC2_HUMAN,tr|B8ZZW2|B8ZZW2_HUMAN" 2 1746.871 -1 22993 24353 2 1746.866085 874.4428 GRIP and coiled-coil domain-containing protein 2 OS=Homo sapiens OX=9606 GN=GCC2 PE=1 SV=4 4.09 3915.2 - 427409 - - - -2.7947 - 2.58 0.436 - 422 1 2 0 -0.0049 16 0 0 0 0.00E+00 0.00E+00 - - - 4.5899 1 221125_WJC_METTL3_EV_vs_WT_F02.24360.24360.3 2.71E-07 18/56 K.GLAPDLPEDLYHLIK[136.11].K "sp|P62277|RS13_HUMAN,tr|J3KMX5|J3KMX5_HUMAN" 2 1700.9229 1.25 22999 24360 3 1700.923571 567.9816 40S ribosomal protein S13 OS=Homo sapiens OX=9606 GN=RPS13 PE=1 SV=2 4.54 3915.9 - 6.93E+06 - - - 0.4104 - 2.74 0.561 - 328.8 1 2 0 0.0007 15 0 0 0 7.30E+07 5.86E+07 - - - 7.4245 1 221125_WJC_METTL3_EV_vs_WT_F02.24362.24362.3 1.44E-08 25/76 K.ALAPTWEQLALGLEHSETVK[136.11].L sp|Q8NBS9|TXND5_HUMAN 1 2200.1619 -1 23001 24362 3 2200.162417 734.3946 Thioredoxin domain-containing protein 5 OS=Homo sapiens OX=9606 GN=TXNDC5 PE=1 SV=2 4.75 3916 - 1.40E+06 - - - 0.2195 - 4.877 0.513 - 612.3 1 2 0 0.0005 20 0 0 0 0.00E+00 0.00E+00 - - - 8.1034 1 221125_WJC_METTL3_EV_vs_WT_F02.24364.24364.4 1.17E-06 16/108 K.SDLEMQYETLQEELMALKK.N "sp|P35527|K1C9_HUMAN,tr|K7EQQ3|K7EQQ3_HUMAN" 2 2298.1123 -1 23003 24364 4 2298.112967 575.5354 "Keratin, type I cytoskeletal 9 OS=Homo sapiens OX=9606 GN=KRT9 PE=1 SV=3" 4.25 3916.2 - 1.26E+06 - - - 0.2746 - 3.291 0.619 - 235.8 1 2 0 0.0006 19 0 0 0 0.00E+00 0.00E+00 - - - 5.0166 1 221125_WJC_METTL3_EV_vs_WT_F02.24365.24365.3 1.32E-09 16/52 K.FDDDFHIYVYDLVK.K "sp|Q99865|SPI2A_HUMAN,sp|Q9BPZ2|SPI2B_HUMAN,sp|Q5JUX0|SPIN3_HUMAN,sp|Q9Y657|SPIN1_HUMAN,tr|A0A087X074|A0A087X074_HUMAN,tr|Q5JZB7|Q5JZB7_HUMAN,tr|A0A1W2PR54|A0A1W2PR54_HUMAN" 7 1787.8407 3.32 23004 24365 3 1787.842975 596.9542 Spindlin-2A OS=Homo sapiens OX=9606 GN=SPIN2A PE=1 SV=3 4.13 3916.3 - 1.25E+06 - - - 1.2988 - 2.826 0.641 - 345.8 1 2 0 0.0023 14 0 0 0 6.11E+06 1.84E+06 - - - 8.4467 1 221125_WJC_METTL3_EV_vs_WT_F02.24367.24367.3 8.44E-07 17/60 K.ELNARPMEVFMC[160.03]SVLK.R "sp|Q9NR31|SAR1A_HUMAN,tr|H0Y5E8|H0Y5E8_HUMAN" 2 1922.9416 0.96 23006 24367 3 1922.942095 641.9878 GTP-binding protein SAR1a OS=Homo sapiens OX=9606 GN=SAR1A PE=1 SV=1 6.23 3916.5 - 1.06E+06 - - - 0.2335 - 2.754 0.601 - 424.3 1 2 0 0.0004 16 0 0 0 8.54E+06 8.89E+06 - - - 7.8398 1 221125_WJC_METTL3_EV_vs_WT_F02.24368.24368.3 2.82E-10 24/72 K.LVNQQLLADPLVPPQLTIK.D "sp|P28331|NDUS1_HUMAN,tr|B4DJ81|B4DJ81_HUMAN" 2 2099.2354 1.45 23007 24368 3 2099.235958 700.7524 "NADH-ubiquinone oxidoreductase 75 kDa subunit, mitochondrial OS=Homo sapiens OX=9606 GN=NDUFS1 PE=1 SV=3" 5.84 3916.6 - 974706 - - - 0.2529 - 3.943 0.576 - 438.4 1 2 0 0.0005 19 0 0 0 3.95E+06 2.72E+06 - - - 8.3323 1 221125_WJC_METTL3_EV_vs_WT_F02.24369.24369.3 2.10E-07 24/72 K.LVNQQLLADPLVPPQLTIK[136.11].D "sp|P28331|NDUS1_HUMAN,tr|B4DJ81|B4DJ81_HUMAN" 2 2107.2496 -1 23008 24369 3 2107.25003 703.4238 "NADH-ubiquinone oxidoreductase 75 kDa subunit, mitochondrial OS=Homo sapiens OX=9606 GN=NDUFS1 PE=1 SV=3" 5.84 3916.8 - 731836 - - - 0.1912 - 3.882 0.586 - 430.4 1 2 0 0.0004 19 0 0 0 0.00E+00 0.00E+00 - - - 8.4055 1 221125_WJC_METTL3_EV_vs_WT_F02.24373.24373.2 5.81E-09 18/30 K.LFIGGLSFETTEESLR.N "sp|P22626|ROA2_HUMAN,tr|A0A7I2YQN4|A0A7I2YQN4_HUMAN,tr|A0A7I2V4N0|A0A7I2V4N0_HUMAN,tr|A0A7I2V4N1|A0A7I2V4N1_HUMAN,tr|A0A7I2V4I6|A0A7I2V4I6_HUMAN,tr|A0A087WUI2|A0A087WUI2_HUMAN,tr|A0A7I2V4S4|A0A7I2V4S4_HUMAN,tr|A0A7I2V323|A0A7I2V323_HUMAN,tr|A0A7I2V3P1|A0A7I2V3P1_HUMAN,tr|A0A7I2V3P7|A0A7I2V3P7_HUMAN" 10 1797.9149 -1 23012 24373 2 1797.91681 899.9647 Heterogeneous nuclear ribonucleoproteins A2\B1 OS=Homo sapiens OX=9606 GN=HNRNPA2B1 PE=1 SV=2 4.25 3917.3 - 651626 - - - 1.0735 - 3.367 0.654 - 1020.3 1 2 0 0.0019 16 0 0 0 0.00E+00 0.00E+00 - - - 6.8556 0.9859 221125_WJC_METTL3_EV_vs_WT_F02.24379.24379.2 0.000244 28-Oct R.MNPNSPSITYDISQL.F "sp|P84090|ERH_HUMAN,tr|G3V279|G3V279_HUMAN" 2 1678.7872 - 23017 24379 2 1678.787624 840.4009 Enhancer of rudimentary homolog OS=Homo sapiens OX=9606 GN=ERH PE=1 SV=1 3.8 3917.9 - 1.55E+07 - - - 0.2305 - 1.708 0.478 - 200.8 1 1 0 0.0004 15 0 0 0 - - - - - 3.8875 1 221125_WJC_METTL3_EV_vs_WT_F02.24381.24381.3 1.19E-05 14/60 R.TMQALEIELQSQLSMK.A "sp|Q04695|K1C17_HUMAN,tr|F5GWP8|F5GWP8_HUMAN" 2 1848.9325 308.37 23019 24381 3 1848.932887 617.3181 "Keratin, type I cytoskeletal 17 OS=Homo sapiens OX=9606 GN=KRT17 PE=1 SV=2" 4.53 3918 - 4.40E+06 - - - 0.198 - 2.916 0.54 - 346.8 1 2 0 0.0004 16 0 0 0 4.98E+07 1.62E+05 - - - 7.3064 0.9999 221125_WJC_METTL3_EV_vs_WT_F02.24383.24383.3 3.00E-05 14/60 K.ELNAR[166.11]PMEVFMC[160.03]SVLK[136.11].R "sp|Q9NR31|SAR1A_HUMAN,tr|H0Y5E8|H0Y5E8_HUMAN" 2 1940.9641 0.96 23021 24383 3 1940.962901 647.9953 GTP-binding protein SAR1a OS=Homo sapiens OX=9606 GN=SAR1A PE=1 SV=1 6.23 3918.1 - 1.76E+06 - - - -0.626 - 2.323 0.443 - 265.2 1 2 0 -0.0012 16 0 0 0 8.64E+06 8.99E+06 - - - 5.6413 1 221125_WJC_METTL3_EV_vs_WT_F02.24386.24386.3 1.19E-05 Sep-52 K.FDDDFHIYVYDLVK[136.11].K "sp|Q99865|SPI2A_HUMAN,sp|Q9BPZ2|SPI2B_HUMAN,sp|Q5JUX0|SPIN3_HUMAN,sp|Q9Y657|SPIN1_HUMAN,tr|A0A087X074|A0A087X074_HUMAN,tr|Q5JZB7|Q5JZB7_HUMAN,tr|A0A1W2PR54|A0A1W2PR54_HUMAN" 7 1795.8549 -1 23024 24386 3 1795.854552 599.6256 Spindlin-2A OS=Homo sapiens OX=9606 GN=SPIN2A PE=1 SV=3 4.13 3918.4 - 1.08E+06 - - - -0.1676 - 1.989 0.536 - 129 1 2 0 -0.0003 14 0 0 0 0.00E+00 0.00E+00 - - - 6.3432 1 221125_WJC_METTL3_EV_vs_WT_F02.24387.24387.3 1.20E-11 19/68 K.VIHDNFGIVEGLMTTVHA.L "sp|P04406|G3P_HUMAN,tr|E7EUT5|E7EUT5_HUMAN" 2 1951.9826 - 23025 24387 3 1951.9832 651.6681 Glyceraldehyde-3-phosphate dehydrogenase OS=Homo sapiens OX=9606 GN=GAPDH PE=1 SV=3 5.15 3918.5 - 1.06E+06 - - - 0.3161 - 3.474 0.615 - 429.3 1 1 0 0.0006 18 0 0 0 - - - - - 8.4974 0.9898 221125_WJC_METTL3_EV_vs_WT_F02.24389.24389.2 8.14E-07 15/28 K.GLAPDLPEDLYHLIK.K "sp|P62277|RS13_HUMAN,tr|J3KMX5|J3KMX5_HUMAN" 2 1692.9087 -1 23027 24389 2 1693.914523 847.4616 40S ribosomal protein S13 OS=Homo sapiens OX=9606 GN=RPS13 PE=1 SV=2 4.54 3918.6 - 1.03E+06 - - - 594.1549 - 2.339 0.501 - 517.7 1 2 0 1.0058 15 0 0 0 0.00E+00 0.00E+00 - - - 4.5146 0.9994 221125_WJC_METTL3_EV_vs_WT_F02.24390.24390.2 1.01E-05 15/28 K.GLAPDLPEDLYHLIK[136.11].K "sp|P62277|RS13_HUMAN,tr|J3KMX5|J3KMX5_HUMAN" 2 1700.9229 1.41 23028 24390 2 1700.928645 851.4687 40S ribosomal protein S13 OS=Homo sapiens OX=9606 GN=RPS13 PE=1 SV=2 4.54 3918.7 - 879809 - - - 3.3935 - 2.345 0.547 - 555.3 1 2 0 0.0058 15 0 0 0 6.90E+06 4.89E+06 - - - 5.1747 1 221125_WJC_METTL3_EV_vs_WT_F02.24392.24392.2 1.21E-07 18/30 R.TMQALEIELQSQLSMK.A "sp|Q04695|K1C17_HUMAN,tr|F5GWP8|F5GWP8_HUMAN" 2 1848.9325 124.87 23030 24392 2 1848.935234 925.4735 "Keratin, type I cytoskeletal 17 OS=Homo sapiens OX=9606 GN=KRT17 PE=1 SV=2" 4.53 3919 - 779729 - - - 1.4673 - 3.957 0.592 - 1573.7 1 2 0 0.0027 16 0 0 0 1.60E+07 1.28E+05 - - - 6.7944 0.9998 221125_WJC_METTL3_EV_vs_WT_F02.24398.24398.2 2.89E-05 Sep-32 R.GIDIQDVSMVVNYDMAK.N sp|Q9BUQ8|DDX23_HUMAN 1 1896.8961 -1 23035 24398 2 1896.895681 949.4553 Probable ATP-dependent RNA helicase DDX23 OS=Homo sapiens OX=9606 GN=DDX23 PE=1 SV=3 3.93 3919.7 - 0 - - - -0.2399 - 1.759 0.512 - 166.8 1 2 0 -0.0005 17 0 0 0 0.00E+00 0.00E+00 - - - 4.2109 0.9994 221125_WJC_METTL3_EV_vs_WT_F02.24399.24399.3 0.00104 Sep-56 K.IPVENILGEVGDGFK.V "sp|Q9H845|ACAD9_HUMAN,tr|A0A7P0T871|A0A7P0T871_HUMAN,tr|A0A7P0T7Z1|A0A7P0T7Z1_HUMAN,tr|A0A7P0T9N9|A0A7P0T9N9_HUMAN,tr|A0A7P0T8U3|A0A7P0T8U3_HUMAN,tr|A0A7P0TB58|A0A7P0TB58_HUMAN,tr|Q9H9W4|Q9H9W4_HUMAN,tr|H0Y8Z9|H0Y8Z9_HUMAN" 8 1585.8352 -1 23036 24399 3 1585.836379 529.619 "Complex I assembly factor ACAD9, mitochondrial OS=Homo sapiens OX=9606 GN=ACAD9 PE=1 SV=1" 4.14 3919.9 - 404390 - - - 0.7599 - 1.663 0.339 - 63.6 1 2 0 0.0012 15 0 0 0 0.00E+00 0.00E+00 - - - 3.6464 1 221125_WJC_METTL3_EV_vs_WT_F02.24404.24404.2 8.55E-08 15/24 K.QIGTFASVEQFWR.F "sp|O60573|IF4E2_HUMAN,tr|B9A044|B9A044_HUMAN,tr|B8ZZ50|B8ZZ50_HUMAN,tr|C9JEL3|C9JEL3_HUMAN" 4 1567.7783 -1 23041 24404 2 1567.780152 784.8964 Eukaryotic translation initiation factor 4E type 2 OS=Homo sapiens OX=9606 GN=EIF4E2 PE=1 SV=1 6 3920.1 - 4.92E+06 - - - 1.1641 - 2.699 0.622 - 860.8 1 2 0 0.0018 13 0 0 0 0.00E+00 0.00E+00 - - - 6.1828 1 221125_WJC_METTL3_EV_vs_WT_F02.24406.24406.3 1.79E-07 18/64 K.LMSSLPNFC[160.03]GIFNHLER.L "sp|Q96PU8|QKI_HUMAN,tr|H0YFB7|H0YFB7_HUMAN" 2 2033.9815 1.55 23043 24406 3 2033.98052 679.0011 Protein quaking OS=Homo sapiens OX=9606 GN=QKI PE=1 SV=1 6.74 3920.2 - 4.18E+06 - - - -0.5 - 3.127 0.563 - 306.1 1 2 0 -0.001 17 0 0 0 3.86E+07 2.49E+07 - - - 7.6968 1 221125_WJC_METTL3_EV_vs_WT_F02.24411.24411.3 3.06E-07 23/64 K.LMSSLPNFC[160.03]GIFNHLER[166.11].L "sp|Q96PU8|QKI_HUMAN,tr|H0YFB7|H0YFB7_HUMAN" 2 2043.9898 1.55 23048 24411 3 2043.987049 682.3372 Protein quaking OS=Homo sapiens OX=9606 GN=QKI PE=1 SV=1 6.74 3920.6 - 2.37E+06 - - - -1.3493 - 3.41 0.568 - 490.8 1 2 0 -0.0028 17 0 0 0 3.86E+07 2.49E+07 - - - 7.9709 1 221125_WJC_METTL3_EV_vs_WT_F02.24414.24414.2 6.90E-09 17/34 R.YYTEFPTVLDITAEDPSK[136.11].S sp|O14929|HAT1_HUMAN 1 2096.0081 -1 23051 24414 2 2096.014961 1049.0113 Histone acetyltransferase type B catalytic subunit OS=Homo sapiens OX=9606 GN=HAT1 PE=1 SV=1 3.92 3920.9 - 1.80E+06 - - - 3.2643 - 2.889 0.567 - 763.8 1 2 0 0.0068 18 0 0 0 0.00E+00 0.00E+00 - - - 5.835 0.9998 221125_WJC_METTL3_EV_vs_WT_F02.24417.24417.3 0.0022 13/72 R.LSPGGYFIGTTPNSFELIR[166.11].R "sp|O43148|MCES_HUMAN,tr|K7EP06|K7EP06_HUMAN" 2 2078.0712 -1 23054 24417 3 2078.071872 693.6977 mRNA cap guanine-N7 methyltransferase OS=Homo sapiens OX=9606 GN=RNMT PE=1 SV=1 6 3921.2 - 1.16E+06 - - - 0.3176 - 2.217 0.377 - 106.8 1 2 0 0.0007 19 0 0 0 0.00E+00 0.00E+00 - - - 4.699 1 221125_WJC_METTL3_EV_vs_WT_F02.24424.24424.3 8.48E-08 20/76 R.IVGLDQVTGMTETAFGSAYK.T sp|P35580|MYH10_HUMAN 1 2087.0245 0.99 23060 24424 3 2087.02451 696.6821 Myosin-10 OS=Homo sapiens OX=9606 GN=MYH10 PE=1 SV=3 4.37 3921.8 - 3.71E+06 - - - 0.0014 - 3.505 0.599 - 471.1 1 2 0 0 20 0 0 0 1.19E+07 1.20E+07 - - - 8.261 1 221125_WJC_METTL3_EV_vs_WT_F02.24425.24425.3 5.38E-09 20/80 K.R[166.11]PLEATFDLGIPQAVLPPLPK[136.11].R "sp|Q9NR56|MBNL1_HUMAN,tr|Q86VM6|Q86VM6_HUMAN,tr|A0A0A0MQX8|A0A0A0MQX8_HUMAN,tr|C9JP00|C9JP00_HUMAN" 4 2289.3216 1.91 23061 24425 3 2289.320978 764.1145 Muscleblind-like protein 1 OS=Homo sapiens OX=9606 GN=MBNL1 PE=1 SV=2 6.07 3921.9 - 2.75E+06 - - - -0.2542 - 3.015 0.667 - 348.5 1 2 0 -0.0006 21 0 0 0 3.87E+07 2.03E+07 - - - 8.6221 1 221125_WJC_METTL3_EV_vs_WT_F02.24427.24427.2 2.11E-15 22/38 R.IVGLDQVTGMTETAFGSAYK.T sp|P35580|MYH10_HUMAN 1 2087.0245 1.04 23063 24427 2 2087.013005 1044.5195 Myosin-10 OS=Homo sapiens OX=9606 GN=MYH10 PE=1 SV=3 4.37 3922.1 - 2.09E+06 - - - -5.5112 - 4.05 0.738 - 1489.4 1 2 0 -0.0115 20 0 0 0 4.38E+06 4.20E+06 - - - 7.9271 0.9998 221125_WJC_METTL3_EV_vs_WT_F02.24437.24437.2 2.28E-08 15/32 K.FDLLASNFPPLPGSSSR[166.11].M "sp|Q71RC2|LARP4_HUMAN,tr|X6RLN4|X6RLN4_HUMAN" 2 1813.9238 1.88 23073 24437 2 1813.919931 907.9692 La-related protein 4 OS=Homo sapiens OX=9606 GN=LARP4 PE=1 SV=3 5.84 3923 - 921919 - - - -2.1434 - 2.645 0.514 - 432.3 1 2 0 -0.0039 17 0 0 0 1.28E+07 6.79E+06 - - - 5.2275 1 221125_WJC_METTL3_EV_vs_WT_F02.24438.24438.3 3.79E-08 14/68 R.SQLDLFDDVGTFASGPPK[136.11].Y "sp|Q8N6H7|ARFG2_HUMAN,tr|E9PQP3|E9PQP3_HUMAN,tr|H0YDN9|H0YDN9_HUMAN,tr|G5E9L0|G5E9L0_HUMAN,tr|A0A0D9SF70|A0A0D9SF70_HUMAN" 5 1900.9298 1.23 23074 24438 3 1900.927903 634.6505 ADP-ribosylation factor GTPase-activating protein 2 OS=Homo sapiens OX=9606 GN=ARFGAP2 PE=1 SV=1 3.93 3923.1 - 897410 - - - -1.0027 - 2.643 0.507 - 273.9 1 2 0 -0.0019 18 0 0 0 4.55E+06 3.71E+06 - - - 6.6122 1 221125_WJC_METTL3_EV_vs_WT_F02.24440.24440.3 1.31E-09 18/68 K.LPDMLNAEIVLGNVQNAK.D "sp|O75643|U520_HUMAN,tr|A0A494C1A5|A0A494C1A5_HUMAN" 2 1938.0244 8.26 23075 24440 3 1938.025449 647.0154 U5 small nuclear ribonucleoprotein 200 kDa helicase OS=Homo sapiens OX=9606 GN=SNRNP200 PE=1 SV=2 4.37 3923.3 - 2.44E+06 - - - 0.5165 - 3.27 0.564 - 272.8 1 2 0 0.001 18 0 0 0 5.79E+06 7.01E+05 - - - 7.778 0.9999 221125_WJC_METTL3_EV_vs_WT_F02.24447.24447.3 2.01E-09 20/96 R.LLEDFGDGGAFPEIHVAQYPLDMGR.K "sp|Q13573|SNW1_HUMAN,tr|G3V3A4|G3V3A4_HUMAN,tr|G3V5R3|G3V5R3_HUMAN" 3 2746.3061 -1 23082 24447 3 2746.298623 916.4426 SNW domain-containing protein 1 OS=Homo sapiens OX=9606 GN=SNW1 PE=1 SV=1 4.1 3923.8 - 2.11E+06 - - - -2.7233 - 3.073 0.514 - 246.6 1 2 0 -0.0075 25 0 0 0 0.00E+00 0.00E+00 - - - 6.8513 1 221125_WJC_METTL3_EV_vs_WT_F02.24450.24450.3 1.27E-06 17/96 R.LLEDFGDGGAFPEIHVAQYPLDMGR[166.11].K "sp|Q13573|SNW1_HUMAN,tr|G3V3A4|G3V3A4_HUMAN,tr|G3V5R3|G3V5R3_HUMAN" 3 2756.3144 -1 23085 24450 3 2756.309191 919.7787 SNW domain-containing protein 1 OS=Homo sapiens OX=9606 GN=SNW1 PE=1 SV=1 4.1 3924.1 - 1.64E+06 - - - -1.8797 - 3.068 0.551 - 241.7 1 2 0 -0.0052 25 0 0 0 0.00E+00 0.00E+00 - - - 7.2607 1 221125_WJC_METTL3_EV_vs_WT_F02.24451.24451.2 4.27E-12 20/34 R.SQLDLFDDVGTFASGPPK.Y "sp|Q8N6H7|ARFG2_HUMAN,tr|E9PQP3|E9PQP3_HUMAN,tr|H0YDN9|H0YDN9_HUMAN,tr|G5E9L0|G5E9L0_HUMAN,tr|A0A0D9SF70|A0A0D9SF70_HUMAN" 5 1892.9156 -1 23086 24451 2 1892.919313 947.4651 ADP-ribosylation factor GTPase-activating protein 2 OS=Homo sapiens OX=9606 GN=ARFGAP2 PE=1 SV=1 3.93 3924.2 - 1.64E+06 - - - 1.9568 - 4.096 0.687 - 1106.1 1 2 0 0.0037 18 0 0 0 0.00E+00 0.00E+00 - - - 7.5806 1 221125_WJC_METTL3_EV_vs_WT_F02.24454.24454.3 1.64E-12 20/72 R.GPLLVQDVVFTDEMAHFDR.E sp|P04040|CATA_HUMAN 1 2188.0623 35.22 23089 24454 3 2188.062973 730.3614 Catalase OS=Homo sapiens OX=9606 GN=CAT PE=1 SV=3 4.22 3924.4 - 1.46E+06 - - - 0.3121 - 3.737 0.703 - 516.4 1 2 0 0.0007 19 0 0 0 5.74E+06 1.63E+05 - - - 9.6163 1 221125_WJC_METTL3_EV_vs_WT_F02.24455.24455.3 2.83E-07 21/72 K.IPNIYAIGDVVAGPMLAHK.A "sp|P09622|DLDH_HUMAN,tr|E9PEX6|E9PEX6_HUMAN" 2 1978.071 1.07 23090 24455 3 1978.070034 660.3643 "Dihydrolipoyl dehydrogenase, mitochondrial OS=Homo sapiens OX=9606 GN=DLD PE=1 SV=2" 6.74 3924.5 - 1.43E+06 - - - -0.4904 - 3.875 0.602 - 803.2 1 2 0 -0.001 19 0 0 0 1.04E+07 9.70E+06 - - - 8.5793 0.9999 221125_WJC_METTL3_EV_vs_WT_F02.24457.24457.3 0.00254 16/56 K.IEVPLYSLLEQTHLK[136.11].V "sp|Q92598|HS105_HUMAN,tr|A0A0A0MSM0|A0A0A0MSM0_HUMAN" 2 1790.0069 0.12 23092 24457 3 1790.004747 597.6763 Heat shock protein 105 kDa OS=Homo sapiens OX=9606 GN=HSPH1 PE=1 SV=1 5.4 3924.7 - 570085 - - - -1.2235 - 2.915 0.37 - 294.4 1 2 0 -0.0022 15 0 0 0 2.19E+07 1.80E+08 - - - 5.4562 1 221125_WJC_METTL3_EV_vs_WT_F02.24461.24461.3 1.23E-06 17/52 K.ANINVENAFFTLAR[166.11].D sp|P61006|RAB8A_HUMAN 1 1588.8237 1.28 23095 24461 3 1588.82418 530.6152 Ras-related protein Rab-8A OS=Homo sapiens OX=9606 GN=RAB8A PE=1 SV=1 6.05 3925.2 - 2.81E+06 - - - 0.2952 - 2.831 0.464 - 306 1 2 0 0.0005 14 0 0 0 9.87E+06 7.73E+06 - - - 6.4785 0.9999 221125_WJC_METTL3_EV_vs_WT_F02.24463.24463.3 1.94E-09 22/68 K.IISSDR[166.11]DLLAVVFYGTEK[136.11].D "sp|P12956|XRCC6_HUMAN,tr|B1AHC9|B1AHC9_HUMAN" 2 2043.1007 -1 23096 24463 3 2043.099719 682.0409 X-ray repair cross-complementing protein 6 OS=Homo sapiens OX=9606 GN=XRCC6 PE=1 SV=2 4.56 3925.5 - 8.02E+06 - - - -0.4934 - 3.511 0.577 - 584.3 1 2 1 -0.001 18 0 0 0 0.00E+00 0.00E+00 - - - 8.1 1 221125_WJC_METTL3_EV_vs_WT_F02.24465.24465.3 1.31E-09 15/52 K.ANINVENAFFTLAR.D sp|P61006|RAB8A_HUMAN 1 1578.8154 1.28 23098 24465 3 1578.816412 527.2791 Ras-related protein Rab-8A OS=Homo sapiens OX=9606 GN=RAB8A PE=1 SV=1 6.05 3925.6 - 3.17E+06 - - - 0.615 - 2.753 0.605 - 199.7 1 2 0 0.001 14 0 0 0 9.87E+06 7.73E+06 - - - 7.9761 0.9997 221125_WJC_METTL3_EV_vs_WT_F02.24466.24466.3 8.44E-05 Dec-60 R.LAQEGIYTLYPFINSR[166.11].L sp|Q08J23|NSUN2_HUMAN 1 1893.9864 1.06 23099 24466 3 1893.989859 632.3361 RNA cytosine C(5)-methyltransferase NSUN2 OS=Homo sapiens OX=9606 GN=NSUN2 PE=1 SV=2 6 3925.6 - 3.14E+06 - - - 1.8163 - 2.188 0.365 - 134.6 1 2 0 0.0034 16 0 0 0 1.01E+07 9.53E+06 - - - 4.6175 1 221125_WJC_METTL3_EV_vs_WT_F02.24471.24471.2 5.07E-10 19/30 R.LAQEGIYTLYPFINSR.L sp|Q08J23|NSUN2_HUMAN 1 1883.9781 -1 23104 24471 2 1883.981592 942.9964 RNA cytosine C(5)-methyltransferase NSUN2 OS=Homo sapiens OX=9606 GN=NSUN2 PE=1 SV=2 6 3926.1 - 1.46E+06 - - - 1.8275 - 3.516 0.5 - 1188.9 1 2 0 0.0034 16 0 0 0 0.00E+00 0.00E+00 - - - 5.8241 0.999 221125_WJC_METTL3_EV_vs_WT_F02.24473.24473.2 5.23E-09 17/30 R.LAQEGIYTLYPFINSR[166.11].L sp|Q08J23|NSUN2_HUMAN 1 1893.9864 -1 23106 24473 2 1893.994291 948.0005 RNA cytosine C(5)-methyltransferase NSUN2 OS=Homo sapiens OX=9606 GN=NSUN2 PE=1 SV=2 6 3926.3 - 1.34E+06 - - - 4.1563 - 3.397 0.441 - 1009.8 1 2 0 0.0079 16 0 0 0 0.00E+00 0.00E+00 - - - 5.3023 0.9931 221125_WJC_METTL3_EV_vs_WT_F02.24475.24475.3 0.0042 Sep-64 K.MSINAEEVVVGDLVEVK[136.11].G sp|P05023|AT1A1_HUMAN 1 1837.9587 1.52 23108 24475 3 1837.953668 613.6602 Sodium\potassium-transporting ATPase subunit alpha-1 OS=Homo sapiens OX=9606 GN=ATP1A1 PE=1 SV=1 4 3926.5 - 1.16E+06 - - - -2.7193 - 1.815 0.242 - 83.8 1 2 0 -0.005 17 0 0 0 5.68E+06 3.73E+06 - - - 2.7426 0.9999 221125_WJC_METTL3_EV_vs_WT_F02.24476.24476.3 2.84E-05 13/64 K.MSINAEEVVVGDLVEVK.G sp|P05023|AT1A1_HUMAN 1 1829.9445 1.41 23109 24476 3 1829.945198 610.9888 Sodium\potassium-transporting ATPase subunit alpha-1 OS=Homo sapiens OX=9606 GN=ATP1A1 PE=1 SV=1 4 3926.6 - 1.16E+06 - - - 0.4 - 2.408 0.447 - 198.3 1 2 0 0.0007 17 0 0 0 5.01E+06 3.55E+06 - - - 5.7435 0.8548 221125_WJC_METTL3_EV_vs_WT_F02.24478.24478.2 0.116 30-Sep K.GLNLPTSITSAAFTLR.T "sp|Q8IVW6|ARI3B_HUMAN,sp|Q99856|ARI3A_HUMAN,tr|K7EJ04|K7EJ04_HUMAN,tr|H3BQ92|H3BQ92_HUMAN" 4 1660.9148 -1 23111 24478 2 1660.927214 831.4647 AT-rich interactive domain-containing protein 3B OS=Homo sapiens OX=9606 GN=ARID3B PE=1 SV=2 9.75 3926.8 - 802695 - - - 7.4616 - 1.726 0.194 - 216.1 1 2 0 0.0124 16 0 0 0 0.00E+00 0.00E+00 - - - 1.8119 0.9999 221125_WJC_METTL3_EV_vs_WT_F02.24479.24479.3 0.00118 Dec-56 K.VSQEILELLNTTTAK[136.11].E "sp|Q86U44|MTA70_HUMAN,tr|H0YFV6|H0YFV6_HUMAN" 2 1666.9233 0.38 23112 24479 3 1666.923527 556.6484 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 4.53 3926.9 - 782916 - - - 0.156 - 2.468 0.358 - 145.5 1 2 0 0.0003 15 0 0 0 2.30E+06 6.11E+06 - - - 4.8886 1 221125_WJC_METTL3_EV_vs_WT_F02.24480.24480.3 3.27E-10 19/52 K.ANVNEILDFFHGYR.L "sp|Q8IXT5|RB12B_HUMAN,tr|B9ZVT1|B9ZVT1_HUMAN" 2 1693.8213 1.77 23113 24480 3 1693.818107 565.6144 RNA-binding protein 12B OS=Homo sapiens OX=9606 GN=RBM12B PE=1 SV=2 5.32 3927.1 - 701134 - - - -1.8585 - 3.41 0.571 - 581.2 1 2 0 -0.0031 14 0 0 0 3.78E+06 2.13E+06 - - - 8.1652 1 221125_WJC_METTL3_EV_vs_WT_F02.24482.24482.3 8.34E-06 13/48 R.VFNVFC[160.03]LYGNVEK[136.11].V "sp|P14866|HNRPL_HUMAN,tr|M0QYT0|M0QYT0_HUMAN,tr|A0A3B3ITJ4|A0A3B3ITJ4_HUMAN,tr|M0QXS5|M0QXS5_HUMAN,tr|M0R076|M0R076_HUMAN" 5 1595.7897 0.94 23115 24482 3 1595.792242 532.9372 Heterogeneous nuclear ribonucleoprotein L OS=Homo sapiens OX=9606 GN=HNRNPL PE=1 SV=2 5.96 3927.3 - 513178 - - - 1.5616 - 2.246 0.531 - 183.4 1 2 0 0.0025 13 0 0 0 1.75E+06 1.87E+06 - - - 6.6533 1 221125_WJC_METTL3_EV_vs_WT_F02.24484.24484.2 6.91E-06 14/26 K.ANINVENAFFTLAR.D sp|P61006|RAB8A_HUMAN 1 1578.8154 -1 23116 24484 2 1578.817986 790.415 Ras-related protein Rab-8A OS=Homo sapiens OX=9606 GN=RAB8A PE=1 SV=1 6.05 3927.5 - 4.05E+06 - - - 1.612 - 2.922 0.613 - 640.7 1 2 0 0.0025 14 0 0 0 0.00E+00 0.00E+00 - - - 6.2586 1 221125_WJC_METTL3_EV_vs_WT_F02.24485.24485.3 3.91E-08 18/80 K.RPLEATFDLGIPQAVLPPLPK.R "sp|Q9NR56|MBNL1_HUMAN,tr|Q86VM6|Q86VM6_HUMAN,tr|A0A0A0MQX8|A0A0A0MQX8_HUMAN,tr|C9JP00|C9JP00_HUMAN" 4 2271.2991 1.91 23117 24485 3 2271.301004 758.107 Muscleblind-like protein 1 OS=Homo sapiens OX=9606 GN=MBNL1 PE=1 SV=2 6.07 3927.6 - 3.56E+06 - - - 0.8427 - 2.837 0.626 - 325.3 1 2 0 0.0019 21 0 0 0 3.87E+07 2.03E+07 - - - 8.0187 1 221125_WJC_METTL3_EV_vs_WT_F02.24486.24486.2 7.48E-06 16/24 K.APDVEQAIEVLTR.S "sp|Q13948|CASP_HUMAN,sp|P39880|CUX1_HUMAN,tr|A0A2R8Y852|A0A2R8Y852_HUMAN,tr|A0A2R8YDI1|A0A2R8YDI1_HUMAN" 4 1439.762 1.39 23118 24486 2 1439.763711 720.8883 Protein CASP OS=Homo sapiens OX=9606 GN=CUX1 PE=1 SV=2 4.14 3927.6 - 8.50E+06 - - - 1.1821 - 3.236 0.598 - 1170.4 1 2 0 0.0017 13 0 0 0 3.57E+07 2.57E+07 - - - 6.4713 1 221125_WJC_METTL3_EV_vs_WT_F02.24488.24488.3 6.30E-06 Dec-52 K.EIVLADVIDNDSWR.L "sp|P22234|PUR6_HUMAN,tr|D6RF62|D6RF62_HUMAN,tr|E9PBS1|E9PBS1_HUMAN" 3 1643.8155 0.84 23120 24488 3 1643.818217 548.9458 Multifunctional protein ADE2 OS=Homo sapiens OX=9606 GN=PAICS PE=1 SV=3 3.84 3927.7 - 1.86E+06 - - - 1.6523 - 2.482 0.521 - 184.9 1 2 0 0.0027 14 0 0 0 4.52E+06 5.36E+06 - - - 6.7638 1 221125_WJC_METTL3_EV_vs_WT_F02.24489.24489.3 2.70E-05 14/52 K.EIVLADVIDNDSWR[166.11].L "sp|P22234|PUR6_HUMAN,tr|D6RF62|D6RF62_HUMAN,tr|E9PBS1|E9PBS1_HUMAN" 3 1653.8238 -1 23121 24489 3 1653.824542 552.2819 Multifunctional protein ADE2 OS=Homo sapiens OX=9606 GN=PAICS PE=1 SV=3 3.84 3927.8 - 1.79E+06 - - - 0.4662 - 3.122 0.553 - 344.1 1 2 0 0.0008 14 0 0 0 0.00E+00 0.00E+00 - - - 7.7307 1 221125_WJC_METTL3_EV_vs_WT_F02.24490.24490.2 8.34E-07 15/24 K.GIDYDFPSLILQK.T "sp|Q9BYG3|MK67I_HUMAN,tr|C9J808|C9J808_HUMAN,tr|C9J6C5|C9J6C5_HUMAN" 3 1507.7922 1.27 23122 24490 2 1507.795039 754.9034 MKI67 FHA domain-interacting nucleolar phosphoprotein OS=Homo sapiens OX=9606 GN=NIFK PE=1 SV=1 4.21 3927.9 - 1.70E+06 - - - 1.8524 - 2.675 0.601 - 658.2 1 2 0 0.0028 13 0 0 0 5.79E+06 4.55E+06 - - - 6.0044 0.9999 221125_WJC_METTL3_EV_vs_WT_F02.24491.24491.2 7.90E-05 13/20 R.ELSDFISYLQR[166.11].E sp|P30101|PDIA3_HUMAN 1 1379.6961 -1 23123 24491 2 1379.696419 690.8553 Protein disulfide-isomerase A3 OS=Homo sapiens OX=9606 GN=PDIA3 PE=1 SV=4 4.37 3928 - 1.50E+06 - - - 0.2667 - 2.244 0.456 - 688.2 1 2 0 0.0004 11 0 0 0 0.00E+00 0.00E+00 - - - 4.5954 0.9999 221125_WJC_METTL3_EV_vs_WT_F02.24494.24494.3 1.28E-08 19/60 R.NVQALEIELQSQLALK.Q "sp|P13645|K1C10_HUMAN,tr|A0A1B0GVI3|A0A1B0GVI3_HUMAN" 2 1796.0044 1174.14 23126 24494 3 1796.011421 599.6754 "Keratin, type I cytoskeletal 10 OS=Homo sapiens OX=9606 GN=KRT10 PE=1 SV=6" 4.53 3928.3 - 828903 - - - 3.9293 - 3.648 0.587 - 636 1 2 0 0.0071 16 0 0 0 3.39E+08 2.89E+05 - - - 8.4032 1 221125_WJC_METTL3_EV_vs_WT_F02.24496.24496.2 6.18E-10 15/24 R.SMEDFVTWVDSSK[136.11].L sp|Q9NV31|IMP3_HUMAN 1 1537.685 -1 23128 24496 2 1537.679198 769.8498 U3 small nucleolar ribonucleoprotein protein IMP3 OS=Homo sapiens OX=9606 GN=IMP3 PE=1 SV=1 4.03 3928.6 - 737133 - - - -3.7797 - 2.848 0.713 - 778.8 1 2 0 -0.0058 13 0 0 0 0.00E+00 0.00E+00 - - - 6.9916 1 221125_WJC_METTL3_EV_vs_WT_F02.24497.24497.2 6.32E-10 15/32 K.MSINAEEVVVGDLVEVK[136.11].G sp|P05023|AT1A1_HUMAN 1 1837.9587 -1 23129 24497 2 1837.959356 919.9866 Sodium\potassium-transporting ATPase subunit alpha-1 OS=Homo sapiens OX=9606 GN=ATP1A1 PE=1 SV=1 4 3928.7 - 729220 - - - 0.3754 - 3.102 0.59 - 755.6 1 2 0 0.0007 17 0 0 0 0.00E+00 0.00E+00 - - - 6.1817 0.9999 221125_WJC_METTL3_EV_vs_WT_F02.24500.24500.3 2.16E-07 18/72 K.IPNIYAIGDVVAGPMLAHK[136.11].A "sp|P09622|DLDH_HUMAN,tr|E9PEX6|E9PEX6_HUMAN" 2 1986.0852 2.35 23132 24500 3 1986.092935 663.0357 "Dihydrolipoyl dehydrogenase, mitochondrial OS=Homo sapiens OX=9606 GN=DLD PE=1 SV=2" 6.74 3929.1 - 544608 - - - 3.8926 - 3.433 0.573 - 549.8 1 2 0 0.0077 19 0 0 0 1.31E+07 5.59E+06 - - - 7.9565 0.9999 221125_WJC_METTL3_EV_vs_WT_F02.24505.24505.3 9.14E-06 14/48 K.APDVEQAIEVLTR[166.11].S "sp|Q13948|CASP_HUMAN,sp|P39880|CUX1_HUMAN,tr|A0A2R8Y852|A0A2R8Y852_HUMAN,tr|A0A2R8YDI1|A0A2R8YDI1_HUMAN" 4 1449.7703 1.42 23136 24505 3 1449.771552 484.264 Protein CASP OS=Homo sapiens OX=9606 GN=CUX1 PE=1 SV=2 4.14 3929.7 - 2.98E+06 - - - 0.8781 - 2.562 0.435 - 331.7 1 2 0 0.0013 13 0 0 0 1.77E+07 1.25E+07 - - - 5.9402 0.9998 221125_WJC_METTL3_EV_vs_WT_F02.24506.24506.3 8.57E-05 Dec-60 R.LAQEGIYTLYPFINSR.L sp|Q08J23|NSUN2_HUMAN 1 1883.9781 -1 23137 24506 3 1883.980991 629 RNA cytosine C(5)-methyltransferase NSUN2 OS=Homo sapiens OX=9606 GN=NSUN2 PE=1 SV=2 6 3929.8 - 562510 - - - 1.5085 - 2.202 0.407 - 130 1 2 0 0.0028 16 0 0 0 0.00E+00 0.00E+00 - - - 5.1023 1 221125_WJC_METTL3_EV_vs_WT_F02.24507.24507.3 2.08E-10 17/64 R.VLDEEEYIEGLQTVIQR.D "sp|Q96DF8|ESS2_HUMAN,tr|F8WEF8|F8WEF8_HUMAN" 2 2033.0317 2.04 23138 24507 3 2033.033929 678.6845 Splicing factor ESS-2 homolog OS=Homo sapiens OX=9606 GN=ESS2 PE=1 SV=1 3.91 3929.8 - 7.00E+06 - - - 1.0959 - 3.115 0.653 - 457.5 1 2 0 0.0022 17 0 0 0 2.58E+07 1.27E+07 - - - 8.6901 0.9998 221125_WJC_METTL3_EV_vs_WT_F02.24508.24508.2 0.00962 18-Nov R.NFIVWLEDQK.L "sp|Q9Y224|RTRAF_HUMAN,tr|G3V4C6|G3V4C6_HUMAN,tr|G3V4E7|G3V4E7_HUMAN" 3 1290.6608 1.3 23139 24508 2 1290.661191 646.3377 "RNA transcription, translation and transport factor protein OS=Homo sapiens OX=9606 GN=RTRAF PE=1 SV=1" 4.37 3929.9 - 6.41E+06 - - - 0.2735 - 2.18 0.366 - 512 1 2 0 0.0004 10 0 0 0 1.75E+07 1.35E+07 - - - 3.9195 0.9997 221125_WJC_METTL3_EV_vs_WT_F02.24509.24509.2 0.000138 18-Oct R.NFIVWLEDQK[136.11].L "sp|Q9Y224|RTRAF_HUMAN,tr|G3V4C6|G3V4C6_HUMAN,tr|G3V4E7|G3V4E7_HUMAN" 3 1298.675 1.3 23140 24509 2 1298.6754 650.3448 "RNA transcription, translation and transport factor protein OS=Homo sapiens OX=9606 GN=RTRAF PE=1 SV=1" 4.37 3929.9 - 3.88E+06 - - - 0.2787 - 2.004 0.364 - 403.4 1 2 0 0.0004 10 0 0 0 1.75E+07 1.35E+07 - - - 3.6698 0.9998 221125_WJC_METTL3_EV_vs_WT_F02.24510.24510.2 7.59E-05 18-Oct K.FAAQELIEVK[136.11].R "sp|Q86U44|MTA70_HUMAN,tr|F5H6D8|F5H6D8_HUMAN,tr|H0YFV6|H0YFV6_HUMAN,tr|B4DTN4|B4DTN4_HUMAN" 4 1154.6427 0.02 23141 24510 2 1154.643416 578.3286 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 4.53 3930 - 3.63E+06 - - - 0.6418 - 2.076 0.478 - 242 1 2 0 0.0007 10 0 0 0 2.69E+05 1.36E+07 - - - 4.6102 1 221125_WJC_METTL3_EV_vs_WT_F02.24513.24513.2 4.50E-05 17/30 R.NVQALEIELQSQLALK.Q "sp|P13645|K1C10_HUMAN,tr|A0A1B0GVI3|A0A1B0GVI3_HUMAN" 2 1796.0044 999 23144 24513 2 1796.004882 899.0095 "Keratin, type I cytoskeletal 10 OS=Homo sapiens OX=9606 GN=KRT10 PE=1 SV=6" 4.53 3930.2 - 2.44E+06 - - - 0.2884 - 3.799 0.613 - 1043.6 1 2 0 0.0005 16 0 0 0 1.04E+08 0.00E+00 - - - 6.85 1 221125_WJC_METTL3_EV_vs_WT_F02.24514.24514.2 1.09E-06 13/28 R.YAVQLINALIQDPAK.E "sp|Q8IWZ3|ANKH1_HUMAN,tr|A0A0A0MQZ8|A0A0A0MQZ8_HUMAN,tr|H0Y472|H0Y472_HUMAN,tr|H0Y7Y3|H0Y7Y3_HUMAN,tr|H0Y4P6|H0Y4P6_HUMAN,tr|H0Y785|H0Y785_HUMAN" 6 1655.9247 1.51 23145 24514 2 1655.924329 828.9696 Ankyrin repeat and KH domain-containing protein 1 OS=Homo sapiens OX=9606 GN=ANKHD1 PE=1 SV=1 5.83 3930.2 - 2.27E+06 - - - -0.1981 - 2.85 0.597 - 585.5 1 2 0 -0.0003 15 0 0 0 9.88E+06 6.53E+06 - - - 6.0252 0.8238 221125_WJC_METTL3_EV_vs_WT_F02.24515.24515.2 9.25E-07 14/32 R.VLDEEEYIEGLQTVIQR[166.11].D "sp|Q96DF8|ESS2_HUMAN,tr|F8WEF8|F8WEF8_HUMAN" 2 2043.04 -1 23146 24515 2 2044.053101 1022.5273 Splicing factor ESS-2 homolog OS=Homo sapiens OX=9606 GN=ESS2 PE=1 SV=1 3.91 3930.4 - 1.21E+06 - - - 495.8934 - 3.063 0.281 - 473.3 1 2 0 1.0131 17 0 0 0 0.00E+00 0.00E+00 - - - 3.5504 1 221125_WJC_METTL3_EV_vs_WT_F02.24516.24516.3 3.96E-08 14/56 R.YAVQLINALIQDPAK[136.11].E "sp|Q8IWZ3|ANKH1_HUMAN,tr|A0A0A0MQZ8|A0A0A0MQZ8_HUMAN,tr|H0Y472|H0Y472_HUMAN,tr|H0Y7Y3|H0Y7Y3_HUMAN,tr|H0Y4P6|H0Y4P6_HUMAN,tr|H0Y785|H0Y785_HUMAN" 6 1663.9389 1.88 23147 24516 3 1663.937282 555.6536 Ankyrin repeat and KH domain-containing protein 1 OS=Homo sapiens OX=9606 GN=ANKHD1 PE=1 SV=1 5.83 3930.4 - 622153 - - - -0.9465 - 2.968 0.527 - 300.5 1 2 0 -0.0016 15 0 0 0 2.64E+06 1.41E+06 - - - 7.2538 1 221125_WJC_METTL3_EV_vs_WT_F02.24518.24518.2 1.47E-08 17/30 R.DSQLYAVDYETLTRPF.S "sp|P82930|RT34_HUMAN,tr|C9JJ19|C9JJ19_HUMAN" 2 1916.9156 -1 23149 24518 2 1916.912434 959.4651 "28S ribosomal protein S34, mitochondrial OS=Homo sapiens OX=9606 GN=MRPS34 PE=1 SV=2" 4.03 3930.7 - 545902 - - - -1.6563 - 3.678 0.631 - 1204.5 1 1 0 -0.0032 16 0 0 0 0.00E+00 0.00E+00 - - - 6.9025 0.9902 221125_WJC_METTL3_EV_vs_WT_F02.24519.24519.2 0.00333 26-Sep K.NLGLEELGIELDPR.G "sp|P09622|DLDH_HUMAN,tr|E9PEX6|E9PEX6_HUMAN" 2 1566.8253 -1 23150 24519 2 1566.832491 784.4199 "Dihydrolipoyl dehydrogenase, mitochondrial OS=Homo sapiens OX=9606 GN=DLD PE=1 SV=2" 4 3930.8 - 526570 - - - 4.5659 - 2.117 0.244 - 147.9 1 2 0 0.0072 14 0 0 0 0.00E+00 0.00E+00 - - - 2.723 1 221125_WJC_METTL3_EV_vs_WT_F02.24520.24520.3 3.10E-08 14/48 K.LFYADHPFIFLVR.D "sp|P50454|SERPH_HUMAN,tr|E9PKH2|E9PKH2_HUMAN,tr|H0YEP8|H0YEP8_HUMAN" 3 1636.8766 -1 23151 24520 3 1636.87786 546.6328 Serpin H1 OS=Homo sapiens OX=9606 GN=SERPINH1 PE=1 SV=2 6.74 3931 - 503275 - - - 0.7789 - 2.763 0.545 - 207.3 1 2 0 0.0013 13 0 0 0 0.00E+00 0.00E+00 - - - 7.3714 1 221125_WJC_METTL3_EV_vs_WT_F02.24522.24522.3 1.55E-08 22/56 K.LPFTPLSYIQGLSHR[166.11].N "sp|Q9UM00|TMCO1_HUMAN,tr|J3QQY2|J3QQY2_HUMAN,tr|J3KS45|J3KS45_HUMAN" 3 1737.9442 0.73 23153 24522 3 1737.948916 580.322 Calcium load-activated calcium channel OS=Homo sapiens OX=9606 GN=TMCO1 PE=1 SV=2 8.75 3931.2 - 516590 - - - 2.736 - 3.439 0.573 - 617.3 1 2 0 0.0048 15 0 0 0 2.05E+06 2.81E+06 - - - 8.1501 0.9954 221125_WJC_METTL3_EV_vs_WT_F02.24523.24523.2 0.0231 Aug-32 K.C[160.03]PFGALSIVNLPSNLEK.E "sp|P61221|ABCE1_HUMAN,tr|D6RGF4|D6RGF4_HUMAN,tr|D6R9I9|D6R9I9_HUMAN" 3 1857.9659 1.24 23154 24523 2 1857.960763 929.9902 ATP-binding cassette sub-family E member 1 OS=Homo sapiens OX=9606 GN=ABCE1 PE=1 SV=1 5.99 3931.4 - 407884 - - - -2.7487 - 1.971 0.201 - 135.6 1 2 0 -0.0051 17 0 0 0 1.95E+06 1.56E+06 - - - 2.1922 0.9998 221125_WJC_METTL3_EV_vs_WT_F02.24526.24526.3 3.33E-05 Oct-44 K.VDLLNQEIEFLK.V sp|P35908|K22E_HUMAN 1 1459.7922 92.79 23156 24526 3 1459.79258 487.6047 "Keratin, type II cytoskeletal 2 epidermal OS=Homo sapiens OX=9606 GN=KRT2 PE=1 SV=2" 4.14 3931.7 - 2.30E+06 - - - 0.2288 - 2.371 0.344 - 236.8 1 2 0 0.0003 12 0 0 0 6.92E+06 7.46E+04 - - - 4.7681 1 221125_WJC_METTL3_EV_vs_WT_F02.24528.24528.3 8.05E-13 22/80 K.WGDAGAEYVVESTGVFTTMEK[136.11].A "sp|P04406|G3P_HUMAN,tr|E7EUT5|E7EUT5_HUMAN" 2 2284.0449 1.04 23158 24528 3 2284.046222 762.3556 Glyceraldehyde-3-phosphate dehydrogenase OS=Homo sapiens OX=9606 GN=GAPDH PE=1 SV=3 4 3931.9 - 9.15E+06 - - - 0.5722 - 3.956 0.665 - 685.2 1 2 0 0.0013 21 0 0 0 4.70E+08 4.51E+08 - - - 9.2508 1 221125_WJC_METTL3_EV_vs_WT_F02.24529.24529.3 1.61E-15 25/80 K.WGDAGAEYVVESTGVFTTMEK.A "sp|P04406|G3P_HUMAN,tr|E7EUT5|E7EUT5_HUMAN" 2 2276.0307 1.04 23159 24529 3 2276.033606 759.6842 Glyceraldehyde-3-phosphate dehydrogenase OS=Homo sapiens OX=9606 GN=GAPDH PE=1 SV=3 4 3931.9 - 8.56E+06 - - - 1.2702 - 4.342 0.71 - 1014.7 1 2 0 0.0029 21 0 0 0 4.70E+08 4.51E+08 - - - 9.9753 1 221125_WJC_METTL3_EV_vs_WT_F02.24533.24533.2 7.80E-12 24/40 K.WGDAGAEYVVESTGVFTTMEK.A "sp|P04406|G3P_HUMAN,tr|E7EUT5|E7EUT5_HUMAN" 2 2276.0307 1.1 23163 24533 2 2276.033666 1139.0226 Glyceraldehyde-3-phosphate dehydrogenase OS=Homo sapiens OX=9606 GN=GAPDH PE=1 SV=3 4 3932.2 - 2.04E+06 - - - 1.2966 - 4.595 0.758 - 2032.5 1 2 0 0.003 21 0 0 0 1.50E+08 1.36E+08 - - - 8.3879 1 221125_WJC_METTL3_EV_vs_WT_F02.24538.24538.3 4.46E-06 19/56 R.EFESVLVDAFSHVAR[166.11].E sp|Q9NQG5|RPR1B_HUMAN 1 1714.8554 2.3 23168 24538 3 1714.854626 572.6257 Regulation of nuclear pre-mRNA domain-containing protein 1B OS=Homo sapiens OX=9606 GN=RPRD1B PE=1 SV=1 4.65 3932.7 - 1.16E+06 - - - -0.4543 - 3.341 0.509 - 652.8 1 2 0 -0.0008 15 0 0 0 5.46E+07 2.37E+07 - - - 7.3622 1 221125_WJC_METTL3_EV_vs_WT_F02.24539.24539.3 5.07E-05 Dec-56 R.YAVQLINALIQDPAK.E "sp|Q8IWZ3|ANKH1_HUMAN,tr|A0A0A0MQZ8|A0A0A0MQZ8_HUMAN,tr|H0Y472|H0Y472_HUMAN,tr|H0Y7Y3|H0Y7Y3_HUMAN,tr|H0Y4P6|H0Y4P6_HUMAN,tr|H0Y785|H0Y785_HUMAN" 6 1655.9247 -1 23169 24539 3 1655.927682 552.9822 Ankyrin repeat and KH domain-containing protein 1 OS=Homo sapiens OX=9606 GN=ANKHD1 PE=1 SV=1 5.83 3932.8 - 1.05E+06 - - - 1.8268 - 2.85 0.496 - 217 1 2 0 0.003 15 0 0 0 0.00E+00 0.00E+00 - - - 6.8019 1 221125_WJC_METTL3_EV_vs_WT_F02.24542.24542.2 3.75E-14 19/38 R.GFGFVTYSC[160.03]VEEVDAAMC[160.03]AR.P "sp|P51991|ROA3_HUMAN,tr|A0A7I2V5D8|A0A7I2V5D8_HUMAN,tr|A0A7I2V2R3|A0A7I2V2R3_HUMAN,tr|A0A7I2V4J6|A0A7I2V4J6_HUMAN,tr|A0A7I2V4G0|A0A7I2V4G0_HUMAN,tr|A0A7I2V402|A0A7I2V402_HUMAN" 6 2267.965 -1 23172 24542 2 2267.961869 1134.9898 Heterogeneous nuclear ribonucleoprotein A3 OS=Homo sapiens OX=9606 GN=HNRNPA3 PE=1 SV=2 4.14 3933.1 - 792982 - - - -1.3633 - 3.898 0.808 - 1280.6 1 1 0 -0.0031 20 0 0 0 0.00E+00 0.00E+00 - - - 8.3527 1 221125_WJC_METTL3_EV_vs_WT_F02.24543.24543.2 2.38E-10 17/34 R.LFQENSVLSSLPLNSLSR.N "sp|O75787|RENR_HUMAN,tr|B7Z413|B7Z413_HUMAN,tr|A0A1B0GTU8|A0A1B0GTU8_HUMAN,tr|A0A1B0GVC7|A0A1B0GVC7_HUMAN,tr|H7C3E1|H7C3E1_HUMAN,tr|A0A1B0GUT7|A0A1B0GUT7_HUMAN,tr|A0A1B0GU12|A0A1B0GU12_HUMAN,tr|A0A1C7CYW4|A0A1C7CYW4_HUMAN,tr|H7C240|H7C240_HUMAN,tr|A0A1B0GVZ1|A0A1B0GVZ1_HUMAN,tr|A0A1B0GVB9|A0A1B0GVB9_HUMAN,tr|A0A1B0GWJ8|A0A1B0GWJ8_HUMAN,tr|A0A1B0GVW0|A0A1B0GVW0_HUMAN,tr|A0A1B0GW13|A0A1B0GW13_HUMAN,tr|A0A1B0GTB0|A0A1B0GTB0_HUMAN,tr|A0A1B0GV60|A0A1B0GV60_HUMAN" 16 2003.0688 -1 23173 24543 2 2003.076703 1002.5417 Renin receptor OS=Homo sapiens OX=9606 GN=ATP6AP2 PE=1 SV=2 6 3933.3 - 624195 - - - 3.9679 - 3.595 0.668 - 734 1 2 0 0.0079 18 0 0 0 0.00E+00 0.00E+00 - - - 7.1182 1 221125_WJC_METTL3_EV_vs_WT_F02.24544.24544.2 3.70E-10 14/36 R.GGLPVSQSQEIFSSLQPFR.S "sp|Q5JSZ5|PRC2B_HUMAN,tr|A0A804HJR4|A0A804HJR4_HUMAN" 2 2076.064 -1 23174 24544 2 2076.070648 1039.0393 Protein PRRC2B OS=Homo sapiens OX=9606 GN=PRRC2B PE=1 SV=2 6 3933.4 - 600240 - - - 3.2003 - 3.096 0.623 - 489.4 1 2 0 0.0066 19 0 0 0 0.00E+00 0.00E+00 - - - 6.4188 0.9999 221125_WJC_METTL3_EV_vs_WT_F02.24547.24547.2 5.95E-06 22-Nov K.VDLLNQEIEFLK.V sp|P35908|K22E_HUMAN 1 1459.7922 999 23176 24547 2 1459.792728 730.9034 "Keratin, type II cytoskeletal 2 epidermal OS=Homo sapiens OX=9606 GN=KRT2 PE=1 SV=2" 4.14 3933.8 - 1.88E+06 - - - 0.3302 - 2.53 0.516 - 583.7 1 2 0 0.0005 12 0 0 0 9.62E+07 0.00E+00 - - - 5.2943 0.9912 221125_WJC_METTL3_EV_vs_WT_F02.24552.24552.2 2.65E-07 15/30 L.SLGLETAGGVMTALIK[136.11].R "sp|P0DMV8|HS71A_HUMAN,sp|P34931|HS71L_HUMAN,sp|P0DMV9|HS71B_HUMAN,tr|Q53FA3|Q53FA3_HUMAN,tr|V9GZ37|V9GZ37_HUMAN,tr|A0A0G2JIW1|A0A0G2JIW1_HUMAN" 6 1567.8735 -1 23181 24552 2 1567.87598 784.944 Heat shock 70 kDa protein 1A OS=Homo sapiens OX=9606 GN=HSPA1A PE=1 SV=1 5.72 3934.1 - 3.00E+06 - - - 1.5945 - 2.92 0.547 - 597.6 1 1 0 0.0025 16 0 0 0 0.00E+00 0.00E+00 - - - 5.7149 0.9971 221125_WJC_METTL3_EV_vs_WT_F02.24553.24553.3 3.61E-07 15/76 R.GFGFVTYSC[160.03]VEEVDAAMC[160.03]AR.P "sp|P51991|ROA3_HUMAN,tr|A0A7I2V5D8|A0A7I2V5D8_HUMAN,tr|A0A7I2V2R3|A0A7I2V2R3_HUMAN,tr|A0A7I2V4J6|A0A7I2V4J6_HUMAN,tr|A0A7I2V4G0|A0A7I2V4G0_HUMAN,tr|A0A7I2V402|A0A7I2V402_HUMAN" 6 2267.965 -1 23182 24553 3 2267.961802 756.9956 Heterogeneous nuclear ribonucleoprotein A3 OS=Homo sapiens OX=9606 GN=HNRNPA3 PE=1 SV=2 4.14 3934.2 - 1.64E+06 - - - -1.3929 - 2.145 0.58 - 173.5 1 1 0 -0.0032 20 0 0 0 0.00E+00 0.00E+00 - - - 6.8569 0.9999 221125_WJC_METTL3_EV_vs_WT_F02.24554.24554.3 9.76E-05 Dec-52 R.AVQTLQMELQQIMK.G "sp|Q06210|GFPT1_HUMAN,tr|A0A6I8PRN4|A0A6I8PRN4_HUMAN,tr|A0A6I8PTT9|A0A6I8PTT9_HUMAN" 3 1659.8688 1.74 23183 24554 3 1659.867732 554.2969 Glutamine--fructose-6-phosphate aminotransferase [isomerizing] 1 OS=Homo sapiens OX=9606 GN=GFPT1 PE=1 SV=3 6.05 3934.3 - 1.51E+06 - - - -0.6428 - 2.663 0.379 - 228.8 1 2 0 -0.0011 14 0 0 0 6.14E+06 3.53E+06 - - - 5.3681 1 221125_WJC_METTL3_EV_vs_WT_F02.24555.24555.2 5.20E-09 16/32 K.LHGGIDILVSNAAVNPF.F "sp|Q6PKH6|DR4L2_HUMAN,sp|Q9BTZ2|DHRS4_HUMAN,tr|F5GWZ1|F5GWZ1_HUMAN,tr|A0A087WSZ6|A0A087WSZ6_HUMAN,tr|E9PFL3|E9PFL3_HUMAN,tr|F6VUV4|F6VUV4_HUMAN" 6 1735.9257 - 23184 24555 2 1735.92729 868.9701 Dehydrogenase\reductase SDR family member 4-like 2 OS=Homo sapiens OX=9606 GN=DHRS4L2 PE=2 SV=2 5.08 3934.4 - 1.33E+06 - - - 0.9044 - 3.04 0.604 - 479.3 1 1 0 0.0016 17 0 0 0 - - - - - 6.2352 1 221125_WJC_METTL3_EV_vs_WT_F02.24556.24556.3 1.04E-10 19/64 M.VGGEAAAAVEELVSGVR.Q sp|Q96HQ2|C2AIL_HUMAN 1 1612.842 1.11 23185 24556 3 1612.838231 538.6213 CDKN2AIP N-terminal-like protein OS=Homo sapiens OX=9606 GN=CDKN2AIPNL PE=1 SV=1 4.25 3934.5 - 1.12E+06 - - - -2.3679 - 3.644 0.557 - 500.3 1 2 0 -0.0038 17 0 0 0 2.74E+06 2.47E+06 - - - 8.0157 0.9889 221125_WJC_METTL3_EV_vs_WT_F02.24557.24557.2 4.96E-05 28-Dec K.EK[136.11]PYFPIPEEYTFIQ.N "sp|Q00839|HNRPU_HUMAN,tr|A0A1W2PQL0|A0A1W2PQL0_HUMAN,tr|A0A1W2PPL4|A0A1W2PPL4_HUMAN,tr|A0A1W2PQ74|A0A1W2PQ74_HUMAN,tr|Q5RI18|Q5RI18_HUMAN,tr|A0A1W2PP35|A0A1W2PP35_HUMAN,tr|A0A1W2PPS1|A0A1W2PPS1_HUMAN,tr|A0A1W2PRZ7|A0A1W2PRZ7_HUMAN,tr|A0A1W2PPH7|A0A1W2PPH7_HUMAN,tr|A0A1W2PP34|A0A1W2PP34_HUMAN,tr|A0A1X7SBS1|A0A1X7SBS1_HUMAN" 11 1907.9437 -1 23186 24557 2 1907.945827 954.9791 Heterogeneous nuclear ribonucleoprotein U OS=Homo sapiens OX=9606 GN=HNRNPU PE=1 SV=6 4.25 3934.7 - 1.02E+06 - - - 1.1316 - 2.28 0.491 - 258.6 1 1 0 0.0022 15 0 0 0 0.00E+00 0.00E+00 - - - 4.6931 1 221125_WJC_METTL3_EV_vs_WT_F02.24558.24558.3 1.91E-05 20/64 M.VGGEAAAAVEELVSGVR[166.11].Q sp|Q96HQ2|C2AIL_HUMAN 1 1622.8503 -1 23187 24558 3 1622.851622 541.9574 CDKN2AIP N-terminal-like protein OS=Homo sapiens OX=9606 GN=CDKN2AIPNL PE=1 SV=1 4.25 3934.8 - 972387 - - - 0.8023 - 3.236 0.487 - 596.6 1 2 0 0.0013 17 0 0 0 0.00E+00 0.00E+00 - - - 6.9359 0.9967 221125_WJC_METTL3_EV_vs_WT_F02.24560.24560.3 3.14E-06 16/60 L.SLGLETAGGVMTALIK[136.11].R "sp|P0DMV8|HS71A_HUMAN,sp|P34931|HS71L_HUMAN,sp|P0DMV9|HS71B_HUMAN,tr|Q53FA3|Q53FA3_HUMAN,tr|V9GZ37|V9GZ37_HUMAN,tr|A0A0G2JIW1|A0A0G2JIW1_HUMAN" 6 1567.8735 0.21 23189 24560 3 1567.8766 523.6318 Heat shock 70 kDa protein 1A OS=Homo sapiens OX=9606 GN=HSPA1A PE=1 SV=1 5.72 3935 - 937074 - - - 1.99 - 2.64 0.567 - 243 1 1 0 0.0031 16 0 0 0 9.21E+05 4.29E+06 - - - 7.3515 0.9994 221125_WJC_METTL3_EV_vs_WT_F02.24561.24561.2 8.12E-07 13/24 K.SDYDMVDYLNELR.E "sp|Q14974|IMB1_HUMAN,tr|J3KTM9|J3KTM9_HUMAN" 2 1631.7137 -1 23190 24561 2 1631.719728 816.8641 Importin subunit beta-1 OS=Homo sapiens OX=9606 GN=KPNB1 PE=1 SV=2 3.84 3935.1 - 892113 - - - 3.671 - 2.375 0.589 - 592 1 2 0 0.006 13 0 0 0 0.00E+00 0.00E+00 - - - 5.6095 0.9999 221125_WJC_METTL3_EV_vs_WT_F02.24562.24562.2 5.27E-08 Dec-34 K.LAYELYTEALGIDPNNIK.T "sp|Q99615|DNJC7_HUMAN,tr|A0A6I8PRZ0|A0A6I8PRZ0_HUMAN,tr|A0A6I8PLE7|A0A6I8PLE7_HUMAN,tr|A0A6I8PR89|A0A6I8PR89_HUMAN,tr|A0A6I8PIK4|A0A6I8PIK4_HUMAN,tr|A0A6I8PUC2|A0A6I8PUC2_HUMAN,tr|A0A6I8PS32|A0A6I8PS32_HUMAN,tr|K7EPP7|K7EPP7_HUMAN,tr|A0A6I8PUD4|A0A6I8PUD4_HUMAN,tr|K7ER44|K7ER44_HUMAN,tr|A0A6I8PU73|A0A6I8PU73_HUMAN,tr|A0A6I8PU89|A0A6I8PU89_HUMAN" 12 2036.0466 -1 23191 24562 2 2036.049024 1019.0306 DnaJ homolog subfamily C member 7 OS=Homo sapiens OX=9606 GN=DNAJC7 PE=1 SV=2 4.14 3935.3 - 749732 - - - 1.1792 - 2.538 0.593 - 277.6 1 2 0 0.0024 18 0 0 0 0.00E+00 0.00E+00 - - - 5.71 0.9992 221125_WJC_METTL3_EV_vs_WT_F02.24563.24563.2 6.39E-09 16/36 K.TTEPGVTGLLLAVEGPAAK[136.11].R "sp|Q14690|RRP5_HUMAN,tr|A0A3B3IUD7|A0A3B3IUD7_HUMAN" 2 1831.0182 -1 23192 24563 2 1831.025537 916.5164 Protein RRP5 homolog OS=Homo sapiens OX=9606 GN=PDCD11 PE=1 SV=3 4.53 3935.4 - 688212 - - - 3.9907 - 2.926 0.53 - 751 1 2 0 0.0073 19 0 0 0 0.00E+00 0.00E+00 - - - 5.5929 1 221125_WJC_METTL3_EV_vs_WT_F02.24564.24564.2 2.30E-12 15/32 K.MSSTFIGNSTAIQELFK.R "sp|Q13509|TBB3_HUMAN,tr|A0A0B4J269|A0A0B4J269_HUMAN" 2 1872.9291 0.91 23193 24564 2 1872.929906 937.4719 Tubulin beta-3 chain OS=Homo sapiens OX=9606 GN=TUBB3 PE=1 SV=2 5.75 3935.5 - 659983 - - - 0.4036 - 3.042 0.652 - 685 1 2 0 0.0008 17 0 0 0 3.01E+06 3.31E+06 - - - 6.5916 1 221125_WJC_METTL3_EV_vs_WT_F02.24565.24565.3 1.90E-05 15/48 R.GQLEANLLQVLEK.V sp|Q6KB66|K2C80_HUMAN 1 1453.814 17 23194 24565 3 1453.813606 485.612 "Keratin, type II cytoskeletal 80 OS=Homo sapiens OX=9606 GN=KRT80 PE=1 SV=2" 4.53 3935.7 - 656645 - - - -0.3013 - 2.882 0.46 - 438.7 1 2 0 -0.0004 13 0 0 0 3.81E+06 2.24E+05 - - - 6.5383 0.9993 221125_WJC_METTL3_EV_vs_WT_F02.24566.24566.2 2.61E-07 Oct-34 R.LFQENSVLSSLPLNSLSR[166.11].N "sp|O75787|RENR_HUMAN,tr|B7Z413|B7Z413_HUMAN,tr|A0A1B0GTU8|A0A1B0GTU8_HUMAN,tr|A0A1B0GVC7|A0A1B0GVC7_HUMAN,tr|H7C3E1|H7C3E1_HUMAN,tr|A0A1B0GUT7|A0A1B0GUT7_HUMAN,tr|A0A1B0GU12|A0A1B0GU12_HUMAN,tr|A0A1C7CYW4|A0A1C7CYW4_HUMAN,tr|H7C240|H7C240_HUMAN,tr|A0A1B0GVZ1|A0A1B0GVZ1_HUMAN,tr|A0A1B0GVB9|A0A1B0GVB9_HUMAN,tr|A0A1B0GWJ8|A0A1B0GWJ8_HUMAN,tr|A0A1B0GVW0|A0A1B0GVW0_HUMAN,tr|A0A1B0GW13|A0A1B0GW13_HUMAN,tr|A0A1B0GTB0|A0A1B0GTB0_HUMAN,tr|A0A1B0GV60|A0A1B0GV60_HUMAN" 16 2013.077 -1 23195 24566 2 2013.069589 1007.5458 Renin receptor OS=Homo sapiens OX=9606 GN=ATP6AP2 PE=1 SV=2 6 3935.8 - 577255 - - - -3.6938 - 2.15 0.584 - 185.4 1 2 0 -0.0074 18 0 0 0 0.00E+00 0.00E+00 - - - 5.234 0.9531 221125_WJC_METTL3_EV_vs_WT_F02.24569.24569.3 0.312 Aug-60 R.NDGAAILAAVSSIAQK.L "sp|P28331|NDUS1_HUMAN,tr|B4DJ81|B4DJ81_HUMAN" 2 1527.8257 1.42 23197 24569 3 1527.826887 510.2825 "NADH-ubiquinone oxidoreductase 75 kDa subunit, mitochondrial OS=Homo sapiens OX=9606 GN=NDUFS1 PE=1 SV=3" 5.84 3936.2 - 213738 - - - 0.7959 - 1.439 0.128 - 53.1 1 2 0 0.0012 16 0 0 0 1.49E+06 1.05E+06 - - - 0.9006 1 221125_WJC_METTL3_EV_vs_WT_F02.24570.24570.2 1.02E-16 24/40 K.WGDAGAEYVVESTGVFTTMEK[136.11].A "sp|P04406|G3P_HUMAN,tr|E7EUT5|E7EUT5_HUMAN" 2 2284.0449 1.1 23198 24570 2 2284.040042 1143.0297 Glyceraldehyde-3-phosphate dehydrogenase OS=Homo sapiens OX=9606 GN=GAPDH PE=1 SV=3 4 3936.3 - 3.73E+07 - - - -2.1335 - 4.562 0.793 - 2160.9 1 2 0 -0.0049 21 0 0 0 1.50E+08 1.36E+08 - - - 8.6281 1 221125_WJC_METTL3_EV_vs_WT_F02.24571.24571.3 1.11E-12 16/76 K.WSTDDVQINDISLQDYIAVK[136.11].E "sp|P46782|RS5_HUMAN,tr|M0R0F0|M0R0F0_HUMAN" 2 2330.1522 1.06 23199 24571 3 2330.147255 777.7247 40S ribosomal protein S5 OS=Homo sapiens OX=9606 GN=RPS5 PE=1 SV=4 3.77 3936.3 - 2.99E+07 - - - -2.1037 - 3.402 0.637 - 318 1 2 0 -0.0049 20 0 0 0 8.15E+07 7.65E+07 - - - 8.6109 1 221125_WJC_METTL3_EV_vs_WT_F02.24572.24572.2 2.40E-13 23/38 K.WSTDDVQINDISLQDYIAVK[136.11].E "sp|P46782|RS5_HUMAN,tr|M0R0F0|M0R0F0_HUMAN" 2 2330.1522 -1 23200 24572 2 2330.147465 1166.0834 40S ribosomal protein S5 OS=Homo sapiens OX=9606 GN=RPS5 PE=1 SV=4 3.77 3936.4 - 9.96E+06 - - - -2.0136 - 4.531 0.727 - 1936.9 1 2 0 -0.0047 20 0 0 0 0.00E+00 0.00E+00 - - - 8.1239 1 221125_WJC_METTL3_EV_vs_WT_F02.24573.24573.2 1.42E-15 21/38 K.WSTDDVQINDISLQDYIAVK.E "sp|P46782|RS5_HUMAN,tr|M0R0F0|M0R0F0_HUMAN" 2 2322.138 1.87 23201 24573 2 2322.134324 1162.0763 40S ribosomal protein S5 OS=Homo sapiens OX=9606 GN=RPS5 PE=1 SV=4 3.77 3936.4 - 9.81E+06 - - - -1.5645 - 4.413 0.744 - 1318.2 1 2 0 -0.0036 20 0 0 0 3.18E+07 1.70E+07 - - - 8.1849 1 221125_WJC_METTL3_EV_vs_WT_F02.24574.24574.2 4.62E-11 15/28 R.DISEASVFDAYVLPK[136.11].L sp|P62854|RS26_HUMAN 1 1660.844 1.01 23202 24574 2 1660.841463 831.4293 40S ribosomal protein S26 OS=Homo sapiens OX=9606 GN=RPS26 PE=1 SV=3 4.03 3936.5 - 9.69E+06 - - - -1.4998 - 2.931 0.653 - 586.6 1 2 0 -0.0025 15 0 0 0 7.66E+07 7.56E+07 - - - 6.5071 1 221125_WJC_METTL3_EV_vs_WT_F02.24575.24575.2 6.80E-10 17/28 R.DISEASVFDAYVLPK.L sp|P62854|RS26_HUMAN 1 1652.8298 1.01 23203 24575 2 1652.826866 827.4222 40S ribosomal protein S26 OS=Homo sapiens OX=9606 GN=RPS26 PE=1 SV=3 4.03 3936.5 - 8.66E+06 - - - -1.7473 - 3.382 0.691 - 722.9 1 2 0 -0.0029 15 0 0 0 7.66E+07 7.56E+07 - - - 7.1395 0.9879 221125_WJC_METTL3_EV_vs_WT_F02.24576.24576.2 1.38E-05 16/28 K.EKPYFPIPEEYTFIQ.N "sp|Q00839|HNRPU_HUMAN,tr|A0A1W2PQL0|A0A1W2PQL0_HUMAN,tr|A0A1W2PPL4|A0A1W2PPL4_HUMAN,tr|A0A1W2PQ74|A0A1W2PQ74_HUMAN,tr|Q5RI18|Q5RI18_HUMAN,tr|A0A1W2PP35|A0A1W2PP35_HUMAN,tr|A0A1W2PPS1|A0A1W2PPS1_HUMAN,tr|A0A1W2PRZ7|A0A1W2PRZ7_HUMAN,tr|A0A1W2PPH7|A0A1W2PPH7_HUMAN,tr|A0A1W2PP34|A0A1W2PP34_HUMAN,tr|A0A1X7SBS1|A0A1X7SBS1_HUMAN" 11 1899.9295 -1 23204 24576 2 1899.925465 950.972 Heterogeneous nuclear ribonucleoprotein U OS=Homo sapiens OX=9606 GN=HNRNPU PE=1 SV=6 4.25 3936.6 - 4.28E+06 - - - -2.1069 - 2.838 0.532 - 504.5 1 1 0 -0.004 15 0 0 0 0.00E+00 0.00E+00 - - - 5.5336 1 221125_WJC_METTL3_EV_vs_WT_F02.24577.24577.2 1.08E-05 15/24 R.NVIVLQTVLQEVR.N "sp|Q9Y2L1|RRP44_HUMAN,tr|F2Z2C0|F2Z2C0_HUMAN" 2 1509.8879 2.28 23205 24577 2 1509.888085 755.9512 Exosome complex exonuclease RRP44 OS=Homo sapiens OX=9606 GN=DIS3 PE=1 SV=2 6 3936.6 - 4.04E+06 - - - 0.1371 - 2.998 0.609 - 951 1 2 0 0.0002 13 0 0 0 1.66E+07 7.28E+06 - - - 6.3569 1 221125_WJC_METTL3_EV_vs_WT_F02.24578.24578.3 1.81E-08 25/92 R.IFLLGLADNEAAIVQAESEETKER.L sp|Q9UHB9|SRP68_HUMAN 1 2645.3548 -1 23206 24578 3 2645.349281 882.7922 Signal recognition particle subunit SRP68 OS=Homo sapiens OX=9606 GN=SRP68 PE=1 SV=2 4.14 3936.7 - 3.45E+06 - - - -2.0961 - 4.207 0.654 - 497.5 1 2 1 -0.0055 24 0 0 0 0.00E+00 0.00E+00 - - - 9.1669 0.9998 221125_WJC_METTL3_EV_vs_WT_F02.24580.24580.2 5.68E-07 16/28 R.EFESVLVDAFSHVAR[166.11].E sp|Q9NQG5|RPR1B_HUMAN 1 1714.8554 1.41 23208 24580 2 1714.851563 858.435 Regulation of nuclear pre-mRNA domain-containing protein 1B OS=Homo sapiens OX=9606 GN=RPRD1B PE=1 SV=1 4.65 3936.9 - 1.15E+06 - - - -2.2404 - 2.433 0.572 - 698.2 1 2 0 -0.0038 15 0 0 0 4.29E+06 3.03E+06 - - - 5.4505 1 221125_WJC_METTL3_EV_vs_WT_F02.24581.24581.3 8.41E-08 14/48 R.NVIVLQTVLQEVR.N "sp|Q9Y2L1|RRP44_HUMAN,tr|F2Z2C0|F2Z2C0_HUMAN" 2 1509.8879 -1 23209 24581 3 1509.885535 504.3032 Exosome complex exonuclease RRP44 OS=Homo sapiens OX=9606 GN=DIS3 PE=1 SV=2 6 3937 - 917679 - - - -1.5518 - 2.91 0.556 - 377.6 1 2 0 -0.0023 13 0 0 0 0.00E+00 0.00E+00 - - - 7.6343 0.9991 221125_WJC_METTL3_EV_vs_WT_F02.24583.24583.2 0.0432 16/28 K.IEVPLYSLLEQTHLK[136.11].V "sp|Q92598|HS105_HUMAN,tr|A0A0A0MSM0|A0A0A0MSM0_HUMAN" 2 1790.0069 0.04 23211 24583 2 1790.001832 896.0107 Heat shock protein 105 kDa OS=Homo sapiens OX=9606 GN=HSPH1 PE=1 SV=1 5.4 3937.3 - 747842 - - - -2.8519 - 2.252 0.399 - 469.6 1 2 0 -0.0051 15 0 0 0 3.11E+05 8.32E+06 - - - 3.9823 0.9999 221125_WJC_METTL3_EV_vs_WT_F02.24584.24584.3 0.0273 14/48 R.NVIVLQTVLQEVR[166.11].N "sp|Q9Y2L1|RRP44_HUMAN,tr|F2Z2C0|F2Z2C0_HUMAN" 2 1519.8961 -1 23212 24584 3 1519.8934 507.6393 Exosome complex exonuclease RRP44 OS=Homo sapiens OX=9606 GN=DIS3 PE=1 SV=2 6 3937.4 - 610576 - - - -1.808 - 2.918 0.373 - 361.8 1 2 0 -0.0027 13 0 0 0 0.00E+00 0.00E+00 - - - 5.6013 1 221125_WJC_METTL3_EV_vs_WT_F02.24592.24592.2 1.07E-06 18/26 K.ALQSVGQIVGEVLK[136.11].Q "sp|P62333|PRS10_HUMAN,tr|A0A087X2I1|A0A087X2I1_HUMAN,tr|H0YJC0|H0YJC0_HUMAN,tr|H0YJE9|H0YJE9_HUMAN,tr|H0YJT1|H0YJT1_HUMAN" 5 1447.849 0.63 23218 24592 2 1447.847313 724.9318 26S proteasome regulatory subunit 10B OS=Homo sapiens OX=9606 GN=PSMC6 PE=1 SV=1 6.05 3938.2 - 4.33E+06 - - - -1.1514 - 3.267 0.566 - 1242.8 1 2 0 -0.0017 14 0 0 0 1.78E+07 2.81E+07 - - - 6.1918 1 221125_WJC_METTL3_EV_vs_WT_F02.24593.24593.3 1.44E-08 17/56 K.IEVPLYSLLEQTHLK.V "sp|Q92598|HS105_HUMAN,tr|A0A0A0MSM0|A0A0A0MSM0_HUMAN" 2 1781.9927 0.12 23219 24593 3 1781.987387 595.0049 Heat shock protein 105 kDa OS=Homo sapiens OX=9606 GN=HSPH1 PE=1 SV=1 5.4 3938.3 - 3.72E+06 - - - -3.0023 - 3.195 0.556 - 339.1 1 2 0 -0.0053 15 0 0 0 2.06E+07 1.76E+08 - - - 7.7684 0.9693 221125_WJC_METTL3_EV_vs_WT_F02.24594.24594.2 0.0011 26-Aug R.QEIEC[160.03]QNQEYSLLL.S "sp|P35527|K1C9_HUMAN,tr|K7EQQ3|K7EQQ3_HUMAN" 2 1765.8193 - 23220 24594 2 1765.816298 883.9169 "Keratin, type I cytoskeletal 9 OS=Homo sapiens OX=9606 GN=KRT9 PE=1 SV=3" 3.67 3938.4 - 3.65E+06 - - - -1.6808 - 1.552 0.463 - 140.1 1 1 0 -0.003 14 0 0 0 - - - - - 3.5628 1 221125_WJC_METTL3_EV_vs_WT_F02.24597.24597.3 3.58E-11 18/88 R.SLLVIPNTLAVNAAQDSTDLVAK[136.11].L "sp|P17987|TCPA_HUMAN,tr|F5H282|F5H282_HUMAN,tr|E7EQR6|E7EQR6_HUMAN" 3 2360.3042 0.49 23223 24597 3 2361.301727 787.7754 T-complex protein 1 subunit alpha OS=Homo sapiens OX=9606 GN=TCP1 PE=1 SV=1 4.21 3938.6 - 2.99E+06 - - - 422.6091 - 3.589 0.648 - 305.6 1 2 0 0.9975 23 0 0 0 1.64E+08 3.35E+08 - - - 8.4861 1 221125_WJC_METTL3_EV_vs_WT_F02.24600.24600.2 6.92E-09 14/22 R.LTLEDLEDSWDR.G "sp|Q6P2Q9|PRP8_HUMAN,tr|I3L3Z8|I3L3Z8_HUMAN" 2 1490.6889 1.16 23226 24600 2 1490.68385 746.3517 Pre-mRNA-processing-splicing factor 8 OS=Homo sapiens OX=9606 GN=PRPF8 PE=1 SV=2 3.77 3938.9 - 2.29E+06 - - - -3.3897 - 2.779 0.625 - 892.1 1 2 0 -0.0051 12 0 0 0 1.33E+07 1.14E+07 - - - 6.345 0.9999 221125_WJC_METTL3_EV_vs_WT_F02.24601.24601.2 2.87E-07 22-Oct R.LTLEDLEDSWDR[166.11].G "sp|Q6P2Q9|PRP8_HUMAN,tr|I3L3Z8|I3L3Z8_HUMAN" 2 1500.6972 1.16 23227 24601 2 1500.695902 751.3559 Pre-mRNA-processing-splicing factor 8 OS=Homo sapiens OX=9606 GN=PRPF8 PE=1 SV=2 3.77 3939 - 2.16E+06 - - - -0.8469 - 2.458 0.581 - 456.5 1 2 0 -0.0013 12 0 0 0 1.33E+07 1.14E+07 - - - 5.6982 1 221125_WJC_METTL3_EV_vs_WT_F02.24603.24603.2 1.69E-09 15/28 R.APDPAYIYDEFLQQR.R "sp|Q14687|GSE1_HUMAN,tr|H0Y613|H0Y613_HUMAN" 2 1824.8683 4.99 23229 24603 2 1824.868428 913.4414 Genetic suppressor element 1 OS=Homo sapiens OX=9606 GN=GSE1 PE=1 SV=3 4.03 3939.2 - 1.22E+06 - - - 0.0893 - 3.08 0.663 - 862.2 1 2 0 0.0002 15 0 0 0 3.99E+06 8.00E+05 - - - 6.7036 1 221125_WJC_METTL3_EV_vs_WT_F02.24604.24604.2 7.44E-07 14/24 K.DAANLLNDALAIR.E "sp|Q07866|KLC1_HUMAN,tr|G3V5R9|G3V5R9_HUMAN,tr|G3V3H3|G3V3H3_HUMAN,tr|F8W6L3|F8W6L3_HUMAN,tr|E7EVH7|E7EVH7_HUMAN,tr|G3V2E7|G3V2E7_HUMAN,tr|G5E9S8|G5E9S8_HUMAN" 7 1368.7361 2.42 23230 24604 2 1368.736375 685.3753 Kinesin light chain 1 OS=Homo sapiens OX=9606 GN=KLC1 PE=1 SV=2 4.21 3939.4 - 1.16E+06 - - - 0.1805 - 3.15 0.543 - 930.7 1 2 0 0.0002 13 0 0 0 1.03E+07 4.27E+06 - - - 5.9964 1 221125_WJC_METTL3_EV_vs_WT_F02.24611.24611.2 1.43E-10 20/44 R.SLLVIPNTLAVNAAQDSTDLVAK[136.11].L "sp|P17987|TCPA_HUMAN,tr|F5H282|F5H282_HUMAN,tr|E7EQR6|E7EQR6_HUMAN" 3 2360.3042 0.5 23235 24611 2 2360.302099 1181.1594 T-complex protein 1 subunit alpha OS=Homo sapiens OX=9606 GN=TCP1 PE=1 SV=1 4.21 3940.2 - 1.05E+07 - - - -0.9075 - 3.686 0.715 - 582.9 1 2 0 -0.0021 23 0 0 0 3.34E+07 6.70E+07 - - - 7.5286 1 221125_WJC_METTL3_EV_vs_WT_F02.24612.24612.3 2.83E-09 25/72 R.DLEK[136.11]PFLLPVEAVYSVPGR[166.11].G sp|P49411|EFTU_HUMAN 1 2146.1793 1.52 23236 24612 3 2146.177826 716.4004 "Elongation factor Tu, mitochondrial OS=Homo sapiens OX=9606 GN=TUFM PE=1 SV=2" 4.68 3940.2 - 8.76E+06 - - - -0.6924 - 3.623 0.636 - 749.4 1 2 0 -0.0015 19 0 0 0 1.31E+08 8.62E+07 - - - 8.793 1 221125_WJC_METTL3_EV_vs_WT_F02.24615.24615.2 4.86E-13 19/44 R.SLLVIPNTLAVNAAQDSTDLVAK.L "sp|P17987|TCPA_HUMAN,tr|F5H282|F5H282_HUMAN,tr|E7EQR6|E7EQR6_HUMAN" 3 2352.29 0.5 23239 24615 2 2352.287705 1177.1523 T-complex protein 1 subunit alpha OS=Homo sapiens OX=9606 GN=TCP1 PE=1 SV=1 4.21 3940.4 - 5.63E+06 - - - -0.9931 - 3.537 0.733 - 628.5 1 2 0 -0.0023 23 0 0 0 3.34E+07 6.70E+07 - - - 7.56 0.9999 221125_WJC_METTL3_EV_vs_WT_F02.24617.24617.3 5.24E-07 15/48 R.TLELQGLINDLQR.E sp|P15924|DESP_HUMAN 1 1511.8308 26.63 23241 24617 3 1511.829117 504.9509 Desmoplakin OS=Homo sapiens OX=9606 GN=DSP PE=1 SV=3 4.37 3940.5 - 3.18E+06 - - - -1.0848 - 2.736 0.367 - 341.3 1 2 0 -0.0016 13 0 0 0 2.11E+07 7.93E+05 - - - 5.3601 1 221125_WJC_METTL3_EV_vs_WT_F02.24621.24621.3 5.01E-12 21/72 R.VLGFSEPTVVTAALNC[160.03]VGK.G sp|O43395|PRPF3_HUMAN 1 1961.0292 -1 23245 24621 3 1961.030661 654.6837 U4\U6 small nuclear ribonucleoprotein Prp3 OS=Homo sapiens OX=9606 GN=PRPF3 PE=1 SV=2 5.97 3940.9 - 2.14E+06 - - - 0.7455 - 3.836 0.545 - 578.6 1 2 0 0.0015 19 0 0 0 0.00E+00 0.00E+00 - - - 7.9188 0.9986 221125_WJC_METTL3_EV_vs_WT_F02.24624.24624.3 4.79E-08 13/60 A.FYLPGLAPVNFC[160.03]DEEK.K sp|Q99805|TM9S2_HUMAN 1 1897.892 2 23248 24624 3 1897.893011 633.638 Transmembrane 9 superfamily member 2 OS=Homo sapiens OX=9606 GN=TM9SF2 PE=1 SV=1 4.14 3941.2 - 1.77E+06 - - - 0.5132 - 2.786 0.592 - 164.6 1 1 0 0.001 16 0 0 0 7.52E+06 3.77E+06 - - - 7.7689 1 221125_WJC_METTL3_EV_vs_WT_F02.24625.24625.2 8.45E-11 17/30 K.DSYLILETLPTEYDSR.V "sp|P17980|PRS6A_HUMAN,tr|R4GNH3|R4GNH3_HUMAN,tr|E9PMD8|E9PMD8_HUMAN,tr|E9PKD5|E9PKD5_HUMAN,tr|E9PLG2|E9PLG2_HUMAN,tr|E9PM69|E9PM69_HUMAN,tr|E9PN50|E9PN50_HUMAN" 7 1913.9258 -1 23249 24625 2 1913.919091 957.9702 26S proteasome regulatory subunit 6A OS=Homo sapiens OX=9606 GN=PSMC3 PE=1 SV=3 3.92 3941.3 - 1.61E+06 - - - -3.5257 - 2.941 0.694 - 978.8 1 2 0 -0.0067 16 0 0 0 0.00E+00 0.00E+00 - - - 6.8169 0.988 221125_WJC_METTL3_EV_vs_WT_F02.24626.24626.3 0.00411 Nov-60 A.FYLPGLAPVNFC[160.03]DEEK[136.11].K sp|Q99805|TM9S2_HUMAN 1 1905.9062 -1 23250 24626 3 1905.9024 636.3094 Transmembrane 9 superfamily member 2 OS=Homo sapiens OX=9606 GN=TM9SF2 PE=1 SV=1 4.14 3941.4 - 1.53E+06 - - - -2.0132 - 2.354 0.441 - 109.3 1 1 0 -0.0038 16 0 0 0 0.00E+00 0.00E+00 - - - 5.6523 1 221125_WJC_METTL3_EV_vs_WT_F02.24627.24627.2 9.99E-13 20/36 R.VLGFSEPTVVTAALNC[160.03]VGK.G sp|O43395|PRPF3_HUMAN 1 1961.0292 -1 23251 24627 2 1961.027576 981.5219 U4\U6 small nuclear ribonucleoprotein Prp3 OS=Homo sapiens OX=9606 GN=PRPF3 PE=1 SV=2 5.97 3941.5 - 1.51E+06 - - - -0.8276 - 3.863 0.662 - 1006.1 1 2 0 -0.0016 19 0 0 0 0.00E+00 0.00E+00 - - - 7.2526 1 221125_WJC_METTL3_EV_vs_WT_F02.24629.24629.2 5.83E-23 24/40 R.NVSDYTPLSLAASGGYVNIIK.L "sp|O75179|ANR17_HUMAN,sp|Q8IWZ3|ANKH1_HUMAN,tr|E9PDP5|E9PDP5_HUMAN,tr|H0YM23|H0YM23_HUMAN,tr|H3BLS9|H3BLS9_HUMAN,tr|H0YLQ3|H0YLQ3_HUMAN,tr|H7C2F5|H7C2F5_HUMAN" 7 2181.1318 1.27 23253 24629 2 2181.129001 1091.5732 Ankyrin repeat domain-containing protein 17 OS=Homo sapiens OX=9606 GN=ANKRD17 PE=1 SV=3 5.83 3941.8 - 981532 - - - -1.2604 - 4.301 0.787 - 1339.5 1 2 0 -0.0027 21 0 0 0 1.28E+07 1.01E+07 - - - 8.4396 0.9278 221125_WJC_METTL3_EV_vs_WT_F02.24631.24631.2 0.198 26-Aug R.ARQEQLQLINNQLR.E "sp|Q9UPQ0|LIMC1_HUMAN,tr|E9PDJ9|E9PDJ9_HUMAN,tr|G5EA03|G5EA03_HUMAN,tr|E7EPK0|E7EPK0_HUMAN,tr|H0Y8P3|H0Y8P3_HUMAN,tr|D6RD46|D6RD46_HUMAN" 6 1722.9489 -1 23254 24631 2 1722.94837 862.4817 LIM and calponin homology domains-containing protein 1 OS=Homo sapiens OX=9606 GN=LIMCH1 PE=1 SV=4 9.64 3942.1 - 504920 - - - -0.3163 - 1.551 0.157 - 83 9 2 1 -0.0005 14 0 0 0 0.00E+00 0.00E+00 - - - 0.8756 1 221125_WJC_METTL3_EV_vs_WT_F02.24633.24633.3 0.000291 14/52 K.QGFDFLC[160.03]MPVFHPR.F "sp|O14744|ANM5_HUMAN,tr|C9JSX3|C9JSX3_HUMAN,tr|G3V580|G3V580_HUMAN,tr|G3V2L6|G3V2L6_HUMAN" 4 1749.812 2.59 23256 24633 3 1749.810537 584.2779 Protein arginine N-methyltransferase 5 OS=Homo sapiens OX=9606 GN=PRMT5 PE=1 SV=4 6.74 3942.3 - 1.54E+07 - - - -0.8092 - 2.563 0.541 - 203.6 1 2 0 -0.0014 14 0 0 0 7.83E+07 3.02E+07 - - - 7.0724 1 221125_WJC_METTL3_EV_vs_WT_F02.24634.24634.2 6.65E-10 17/26 K.LTVQEEQIVELIEK[136.11].L "sp|P52732|KIF11_HUMAN,tr|A0A7I2YQY4|A0A7I2YQY4_HUMAN,tr|A0A7I2V3A9|A0A7I2V3A9_HUMAN,tr|A0A7I2V3V3|A0A7I2V3V3_HUMAN" 4 1677.928 4.81 23257 24634 2 1677.924551 839.9713 Kinesin-like protein KIF11 OS=Homo sapiens OX=9606 GN=KIF11 PE=1 SV=2 4.09 3942.3 - 1.43E+07 - - - -2.0662 - 3.589 0.584 - 1203.8 1 2 0 -0.0035 14 0 0 0 3.12E+08 6.48E+07 - - - 6.5601 1 221125_WJC_METTL3_EV_vs_WT_F02.24636.24636.3 6.69E-08 17/52 K.LTVQEEQIVELIEK[136.11].L "sp|P52732|KIF11_HUMAN,tr|A0A7I2YQY4|A0A7I2YQY4_HUMAN,tr|A0A7I2V3A9|A0A7I2V3A9_HUMAN,tr|A0A7I2V3V3|A0A7I2V3V3_HUMAN" 4 1677.928 4.82 23259 24636 3 1677.926084 560.3166 Kinesin-like protein KIF11 OS=Homo sapiens OX=9606 GN=KIF11 PE=1 SV=2 4.09 3942.4 - 8.42E+06 - - - -1.1526 - 3.102 0.529 - 554.9 1 2 0 -0.0019 14 0 0 0 1.62E+08 3.36E+07 - - - 7.4457 1 221125_WJC_METTL3_EV_vs_WT_F02.24637.24637.3 3.12E-16 20/80 R.NVSDYTPLSLAASGGYVNIIK.L "sp|O75179|ANR17_HUMAN,sp|Q8IWZ3|ANKH1_HUMAN,tr|E9PDP5|E9PDP5_HUMAN,tr|H0YM23|H0YM23_HUMAN,tr|H3BLS9|H3BLS9_HUMAN,tr|H0YLQ3|H0YLQ3_HUMAN,tr|H7C2F5|H7C2F5_HUMAN" 7 2181.1318 1.5 23260 24637 3 2181.131357 728.0512 Ankyrin repeat domain-containing protein 17 OS=Homo sapiens OX=9606 GN=ANKRD17 PE=1 SV=3 5.83 3942.5 - 5.98E+06 - - - -0.1802 - 3.966 0.708 - 288.2 1 2 0 -0.0004 21 0 0 0 3.06E+07 2.05E+07 - - - 9.7365 1 221125_WJC_METTL3_EV_vs_WT_F02.24639.24639.3 4.25E-13 24/92 R.LVEGILHAPDAGWGNLVYVVNYPK.D "sp|Q13148|TADBP_HUMAN,tr|A0A087WX29|A0A087WX29_HUMAN,tr|K7EJ99|K7EJ99_HUMAN,tr|G3V162|G3V162_HUMAN,tr|A0A0A0MSV7|A0A0A0MSV7_HUMAN,tr|A0A087WYY0|A0A087WYY0_HUMAN,tr|K7EN94|K7EN94_HUMAN,tr|A0A0A0N0M3|A0A0A0N0M3_HUMAN,tr|B1AKP7|B1AKP7_HUMAN,tr|K7EJM5|K7EJM5_HUMAN,tr|A0A087X260|A0A087X260_HUMAN" 11 2623.3799 1.66 23262 24639 3 2623.379566 875.4672 TAR DNA-binding protein 43 OS=Homo sapiens OX=9606 GN=TARDBP PE=1 SV=1 5.32 3942.6 - 4.20E+06 - - - -0.1117 - 4.431 0.668 - 541.8 1 2 0 -0.0003 24 0 0 0 9.62E+07 5.80E+07 - - - 9.4449 0.9992 221125_WJC_METTL3_EV_vs_WT_F02.24640.24640.3 6.48E-08 15/72 R.EYFGGFGEVESIELPMDNK.T "sp|Q14103|HNRPD_HUMAN,tr|H0Y8G5|H0Y8G5_HUMAN,tr|D6RAF8|D6RAF8_HUMAN,tr|H0YA96|H0YA96_HUMAN" 4 2159.9721 1.85 23263 24640 3 2160.97333 720.998 Heterogeneous nuclear ribonucleoprotein D0 OS=Homo sapiens OX=9606 GN=HNRNPD PE=1 SV=1 3.91 3942.6 - 3.97E+06 - - - 463.5213 - 2.927 0.51 - 153.8 1 2 0 1.0012 19 0 0 0 2.67E+07 1.44E+07 - - - 6.5872 1 221125_WJC_METTL3_EV_vs_WT_F02.24642.24642.3 2.40E-06 27/92 R.LVEGILHAPDAGWGNLVYVVNYPK[136.11].D "sp|Q13148|TADBP_HUMAN,tr|A0A087WX29|A0A087WX29_HUMAN,tr|K7EJ99|K7EJ99_HUMAN,tr|G3V162|G3V162_HUMAN,tr|A0A0A0MSV7|A0A0A0MSV7_HUMAN,tr|A0A087WYY0|A0A087WYY0_HUMAN,tr|K7EN94|K7EN94_HUMAN,tr|A0A0A0N0M3|A0A0A0N0M3_HUMAN,tr|B1AKP7|B1AKP7_HUMAN,tr|K7EJM5|K7EJM5_HUMAN,tr|A0A087X260|A0A087X260_HUMAN" 11 2631.3941 1.66 23265 24642 3 2631.392052 878.1386 TAR DNA-binding protein 43 OS=Homo sapiens OX=9606 GN=TARDBP PE=1 SV=1 5.32 3942.8 - 2.80E+06 - - - -0.7627 - 4.629 0.606 - 825.6 1 2 0 -0.002 24 0 0 0 9.57E+07 5.78E+07 - - - 8.8548 1 221125_WJC_METTL3_EV_vs_WT_F02.24643.24643.2 7.64E-15 23/36 R.EYFGGFGEVESIELPMDNK.T "sp|Q14103|HNRPD_HUMAN,tr|H0Y8G5|H0Y8G5_HUMAN,tr|D6RAF8|D6RAF8_HUMAN,tr|H0YA96|H0YA96_HUMAN" 4 2159.9721 -1 23266 24643 2 2159.969083 1080.9933 Heterogeneous nuclear ribonucleoprotein D0 OS=Homo sapiens OX=9606 GN=HNRNPD PE=1 SV=1 3.91 3942.9 - 2.13E+06 - - - -1.4139 - 3.919 0.704 - 919.7 1 2 0 -0.0031 19 0 0 0 0.00E+00 0.00E+00 - - - 7.5978 0.9999 221125_WJC_METTL3_EV_vs_WT_F02.24644.24644.3 3.61E-06 15/48 K.K[136.11]VGYTPDWIFLLR[166.11].N "sp|Q00610|CLH1_HUMAN,sp|P53675|CLH2_HUMAN,tr|A0A087WVQ6|A0A087WVQ6_HUMAN,tr|A0A087WX41|A0A087WX41_HUMAN" 4 1624.9096 0.69 23267 24644 3 1624.90638 542.6438 Clathrin heavy chain 1 OS=Homo sapiens OX=9606 GN=CLTC PE=1 SV=5 8.59 3943 - 1.93E+06 - - - -1.9933 - 2.902 0.369 - 292.4 1 2 0 -0.0032 13 0 0 0 3.76E+06 5.47E+06 - - - 5.5417 0.9999 221125_WJC_METTL3_EV_vs_WT_F02.24645.24645.3 0.000263 13/72 R.VLGFSEPTVVTAALNC[160.03]VGK[136.11].G sp|O43395|PRPF3_HUMAN 1 1969.0434 1.54 23268 24645 3 1969.044189 657.3551 U4\U6 small nuclear ribonucleoprotein Prp3 OS=Homo sapiens OX=9606 GN=PRPF3 PE=1 SV=2 5.97 3943.1 - 1.75E+06 - - - 0.4012 - 2.237 0.421 - 161.6 1 2 0 0.0008 19 0 0 0 9.85E+06 6.40E+06 - - - 5.2116 1 221125_WJC_METTL3_EV_vs_WT_F02.24646.24646.4 6.83E-07 21/108 R.DLEKPFLLPVEAVYSVPGR.G sp|P49411|EFTU_HUMAN 1 2128.1568 1.44 23269 24646 4 2128.152773 533.0465 "Elongation factor Tu, mitochondrial OS=Homo sapiens OX=9606 GN=TUFM PE=1 SV=2" 4.68 3943.2 - 1.69E+06 - - - -1.912 - 3.178 0.567 - 285.1 1 2 0 -0.0041 19 0 0 0 4.22E+06 2.93E+06 - - - 4.5512 1 221125_WJC_METTL3_EV_vs_WT_F02.24648.24648.3 1.87E-08 15/44 K.ADVFHAYLSLLK[136.11].Q "sp|Q86VP6|CAND1_HUMAN,tr|H0YH27|H0YH27_HUMAN,tr|A0A0C4DGH5|A0A0C4DGH5_HUMAN" 3 1383.7642 0.8 23271 24648 3 1383.76155 462.262 Cullin-associated NEDD8-dissociated protein 1 OS=Homo sapiens OX=9606 GN=CAND1 PE=1 SV=2 6.79 3943.3 - 1.27E+06 - - - -1.9057 - 2.909 0.556 - 366.5 1 2 0 -0.0026 12 0 0 0 3.51E+06 4.37E+06 - - - 7.6979 1 221125_WJC_METTL3_EV_vs_WT_F02.24650.24650.2 2.83E-10 14/36 R.VLGFSEPTVVTAALNC[160.03]VGK[136.11].G sp|O43395|PRPF3_HUMAN 1 1969.0434 -1 23273 24650 2 1969.039214 985.529 U4\U6 small nuclear ribonucleoprotein Prp3 OS=Homo sapiens OX=9606 GN=PRPF3 PE=1 SV=2 5.97 3943.6 - 1.05E+06 - - - -2.1254 - 2.908 0.574 - 474.2 1 2 0 -0.0042 19 0 0 0 0.00E+00 0.00E+00 - - - 5.9037 1 221125_WJC_METTL3_EV_vs_WT_F02.24652.24652.3 1.57E-08 23/72 R.DLEKPFLLPVEAVYSVPGR.G sp|P49411|EFTU_HUMAN 1 2128.1568 1.52 23274 24652 3 2128.155499 710.3929 "Elongation factor Tu, mitochondrial OS=Homo sapiens OX=9606 GN=TUFM PE=1 SV=2" 4.68 3943.8 - 3.72E+07 - - - -0.6311 - 3.258 0.576 - 561.1 1 2 0 -0.0013 19 0 0 0 1.31E+08 8.62E+07 - - - 7.8632 1 221125_WJC_METTL3_EV_vs_WT_F02.24656.24656.3 0.00093 Dec-52 K.NSHLINVLMWELEK[136.11].K "sp|O15372|EIF3H_HUMAN,tr|B3KS98|B3KS98_HUMAN,tr|A0A087WZK9|A0A087WZK9_HUMAN,tr|E5RJT0|E5RJT0_HUMAN" 4 1732.9062 1.8 23278 24656 3 1732.906711 578.6427 Eukaryotic translation initiation factor 3 subunit H OS=Homo sapiens OX=9606 GN=EIF3H PE=1 SV=1 5.4 3944.1 - 3.23E+06 - - - 0.3082 - 2.848 0.459 - 273.6 1 2 0 0.0005 14 0 0 0 2.10E+07 1.17E+07 - - - 6.4387 1 221125_WJC_METTL3_EV_vs_WT_F02.24658.24658.2 6.03E-14 26/44 K.IMQSSSEVGYDAMAGDFVNMVEK.G "sp|P10809|CH60_HUMAN,tr|A0A7I2V2X6|A0A7I2V2X6_HUMAN,tr|A0A7I2YQK6|A0A7I2YQK6_HUMAN,tr|A0A7I2V599|A0A7I2V599_HUMAN" 4 2507.1018 -1 23280 24658 2 2507.099667 1254.5582 "60 kDa heat shock protein, mitochondrial OS=Homo sapiens OX=9606 GN=HSPD1 PE=1 SV=2" 3.92 3944.3 - 2.92E+06 - - - -0.8699 - 4.613 0.771 - 2066.5 1 2 0 -0.0022 23 0 0 0 0.00E+00 0.00E+00 - - - 8.4937 1 221125_WJC_METTL3_EV_vs_WT_F02.24660.24660.3 0.000168 13/68 K.ENIIAVATTNNLYIFQDK[136.11].V "sp|P63151|2ABA_HUMAN,tr|A0A590UJJ1|A0A590UJJ1_HUMAN,tr|A0A590UJY3|A0A590UJY3_HUMAN" 3 2074.0826 -1 23282 24660 3 2074.082773 692.3682 Serine\threonine-protein phosphatase 2A 55 kDa regulatory subunit B alpha isoform OS=Homo sapiens OX=9606 GN=PPP2R2A PE=1 SV=1 4.37 3944.4 - 2.11E+06 - - - 0.0733 - 2.768 0.46 - 246.4 1 2 0 0.0002 18 0 0 0 0.00E+00 0.00E+00 - - - 6.2037 1 221125_WJC_METTL3_EV_vs_WT_F02.24662.24662.3 1.86E-06 13/44 K.ADVFHAYLSLLK.Q "sp|Q86VP6|CAND1_HUMAN,tr|H0YH27|H0YH27_HUMAN,tr|A0A0C4DGH5|A0A0C4DGH5_HUMAN" 3 1375.75 0.8 23284 24662 3 1375.747875 459.5906 Cullin-associated NEDD8-dissociated protein 1 OS=Homo sapiens OX=9606 GN=CAND1 PE=1 SV=2 6.79 3944.5 - 1.87E+06 - - - -1.5352 - 2.466 0.509 - 320.2 1 2 0 -0.0021 12 0 0 0 3.51E+06 4.37E+06 - - - 6.7161 0.9998 221125_WJC_METTL3_EV_vs_WT_F02.24666.24666.3 0.000234 Aug-48 K.KVGYTPDWIFLLR.N "sp|Q00610|CLH1_HUMAN,sp|P53675|CLH2_HUMAN,tr|A0A087WVQ6|A0A087WVQ6_HUMAN,tr|A0A087WX41|A0A087WX41_HUMAN" 4 1606.8871 0.69 23288 24666 3 1606.884081 536.6363 Clathrin heavy chain 1 OS=Homo sapiens OX=9606 GN=CLTC PE=1 SV=5 8.59 3944.9 - 1.54E+06 - - - -1.9093 - 2.049 0.426 - 98.6 1 2 0 -0.0031 13 0 0 0 3.76E+06 5.47E+06 - - - 5.2336 0.9999 221125_WJC_METTL3_EV_vs_WT_F02.24671.24671.2 9.98E-07 14/24 K.AVSDWLIASVEGR.L "sp|Q969V3|NCLN_HUMAN,tr|K7EMW4|K7EMW4_HUMAN,tr|K7ENM2|K7ENM2_HUMAN" 3 1401.7252 -1 23293 24671 2 1401.723186 701.8699 Nicalin OS=Homo sapiens OX=9606 GN=NCLN PE=1 SV=2 4.37 3945.4 - 622874 - - - -1.4575 - 2.926 0.523 - 691.7 1 2 0 -0.002 13 0 0 0 0.00E+00 0.00E+00 - - - 5.6588 1 221125_WJC_METTL3_EV_vs_WT_F02.24675.24675.2 2.07E-10 15/28 R.GFGFVTFMDQAGVDK[136.11].V sp|O43347|MSI1H_HUMAN 1 1625.7639 1.36 23295 24675 2 1625.762036 813.8892 RNA-binding protein Musashi homolog 1 OS=Homo sapiens OX=9606 GN=MSI1 PE=1 SV=1 4.21 3945.9 - 2.31E+07 - - - -1.1644 - 3.042 0.663 - 709.6 1 2 0 -0.0019 15 0 0 0 1.21E+08 8.94E+07 - - - 6.6725 1 221125_WJC_METTL3_EV_vs_WT_F02.24676.24676.3 4.03E-07 19/68 R.QATTIIADNIIFLSDQTK.E sp|Q04837|SSBP_HUMAN 1 1991.0575 1.38 23296 24676 3 1991.057876 664.6931 "Single-stranded DNA-binding protein, mitochondrial OS=Homo sapiens OX=9606 GN=SSBP1 PE=1 SV=1" 4.21 3946 - 1.08E+07 - - - 0.1778 - 3.003 0.45 - 501.9 1 2 0 0.0004 18 0 0 0 9.82E+07 7.10E+07 - - - 6.2951 1 221125_WJC_METTL3_EV_vs_WT_F02.24677.24677.2 3.44E-08 28-Dec R.GFGFVTFMDQAGVDK.V sp|O43347|MSI1H_HUMAN 1 1617.7497 1.36 23297 24677 2 1617.749313 809.8821 RNA-binding protein Musashi homolog 1 OS=Homo sapiens OX=9606 GN=MSI1 PE=1 SV=1 4.21 3946 - 3.35E+07 - - - -0.2571 - 2.898 0.664 - 469.3 1 2 0 -0.0004 15 0 0 0 1.21E+08 8.94E+07 - - - 6.5611 1 221125_WJC_METTL3_EV_vs_WT_F02.24678.24678.3 5.38E-09 17/64 R.VFEVSLADLQNDEVAFR.K "sp|P61247|RS3A_HUMAN,tr|H0Y8L7|H0Y8L7_HUMAN,tr|D6RI02|D6RI02_HUMAN,tr|D6RED7|D6RED7_HUMAN,tr|D6RGE0|D6RGE0_HUMAN,tr|D6RAS7|D6RAS7_HUMAN,tr|D6RB09|D6RB09_HUMAN,tr|E9PFI5|E9PFI5_HUMAN,tr|D6RAT0|D6RAT0_HUMAN,tr|D6RG13|D6RG13_HUMAN" 10 1950.9687 1.18 23298 24678 3 1950.967619 651.3302 40S ribosomal protein S3a OS=Homo sapiens OX=9606 GN=RPS3A PE=1 SV=2 3.92 3946.1 - 7.69E+06 - - - -0.5577 - 3.324 0.66 - 510.9 1 2 0 -0.0011 17 0 0 0 2.99E+07 2.54E+07 - - - 8.9326 1 221125_WJC_METTL3_EV_vs_WT_F02.24679.24679.3 0.0319 17/48 R.IAELLTELHQLIK[136.11].Q "sp|Q96ES7|SGF29_HUMAN,tr|H3BPL5|H3BPL5_HUMAN" 2 1527.9116 1.12 23299 24679 3 1527.911449 510.3111 SAGA-associated factor 29 OS=Homo sapiens OX=9606 GN=SGF29 PE=1 SV=1 5.4 3946.1 - 5.48E+06 - - - -0.0857 - 3.479 0.467 - 530.2 1 2 0 -0.0001 13 0 0 0 1.45E+07 1.29E+07 - - - 7.1268 1 221125_WJC_METTL3_EV_vs_WT_F02.24680.24680.3 8.36E-06 Oct-52 K.NSHLINVLMWELEK.K "sp|O15372|EIF3H_HUMAN,tr|B3KS98|B3KS98_HUMAN,tr|A0A087WZK9|A0A087WZK9_HUMAN,tr|E5RJT0|E5RJT0_HUMAN" 4 1724.892 1.8 23300 24680 3 1724.893597 575.9713 Eukaryotic translation initiation factor 3 subunit H OS=Homo sapiens OX=9606 GN=EIF3H PE=1 SV=1 5.4 3946.1 - 5.30E+06 - - - 0.9392 - 2.548 0.462 - 192.6 1 2 0 0.0016 14 0 0 0 2.10E+07 1.17E+07 - - - 6.176 1 221125_WJC_METTL3_EV_vs_WT_F02.24681.24681.2 2.71E-09 22/32 R.VFEVSLADLQNDEVAFR.K "sp|P61247|RS3A_HUMAN,tr|H0Y8L7|H0Y8L7_HUMAN,tr|D6RI02|D6RI02_HUMAN,tr|D6RED7|D6RED7_HUMAN,tr|D6RGE0|D6RGE0_HUMAN,tr|D6RAS7|D6RAS7_HUMAN,tr|D6RB09|D6RB09_HUMAN,tr|E9PFI5|E9PFI5_HUMAN,tr|D6RAT0|D6RAT0_HUMAN,tr|D6RG13|D6RG13_HUMAN" 10 1950.9687 -1 23301 24681 2 1950.969787 976.4916 40S ribosomal protein S3a OS=Homo sapiens OX=9606 GN=RPS3A PE=1 SV=2 3.92 3946.2 - 5.08E+06 - - - 0.5536 - 3.864 0.683 - 2026 1 2 0 0.0011 17 0 0 0 0.00E+00 0.00E+00 - - - 7.4085 1 221125_WJC_METTL3_EV_vs_WT_F02.24682.24682.3 1.56E-05 13/56 R.GFGFVTFMDQAGVDK.V sp|O43347|MSI1H_HUMAN 1 1617.7497 1.81 23302 24682 3 1617.7487 540.2572 RNA-binding protein Musashi homolog 1 OS=Homo sapiens OX=9606 GN=MSI1 PE=1 SV=1 4.21 3946.3 - 2.43E+06 - - - -0.6361 - 2.031 0.541 - 136 1 2 0 -0.001 15 0 0 0 7.46E+06 4.11E+06 - - - 6.4201 1 221125_WJC_METTL3_EV_vs_WT_F02.24684.24684.2 2.15E-09 22/34 R.QATTIIADNIIFLSDQTK.E sp|Q04837|SSBP_HUMAN 1 1991.0575 -1 23304 24684 2 1991.058127 996.536 "Single-stranded DNA-binding protein, mitochondrial OS=Homo sapiens OX=9606 GN=SSBP1 PE=1 SV=1" 4.21 3946.5 - 1.90E+06 - - - 0.3039 - 3.824 0.62 - 1862.8 1 2 0 0.0006 18 0 0 0 0.00E+00 0.00E+00 - - - 6.9178 1 221125_WJC_METTL3_EV_vs_WT_F02.24685.24685.3 4.77E-09 16/56 R.GFGFVTFMDQAGVDK[136.11].V sp|O43347|MSI1H_HUMAN 1 1625.7639 -1 23305 24685 3 1625.763616 542.9286 RNA-binding protein Musashi homolog 1 OS=Homo sapiens OX=9606 GN=MSI1 PE=1 SV=1 4.21 3946.6 - 1.84E+06 - - - -0.1925 - 2.727 0.599 - 255.7 1 2 0 -0.0003 15 0 0 0 0.00E+00 0.00E+00 - - - 7.8359 1 221125_WJC_METTL3_EV_vs_WT_F02.24686.24686.2 2.46E-10 24-Dec R.FQQAVDAVEEFLR[166.11].R "sp|Q49A26|GLYR1_HUMAN,tr|K7EMM8|K7EMM8_HUMAN,tr|K7EQB2|K7EQB2_HUMAN" 3 1560.7812 0.38 23306 24686 2 1560.780453 781.3979 Putative oxidoreductase GLYR1 OS=Homo sapiens OX=9606 GN=GLYR1 PE=1 SV=4 4.14 3946.7 - 1.83E+06 - - - -0.4645 - 3.11 0.527 - 401.8 1 2 0 -0.0007 13 0 0 0 4.59E+06 1.22E+07 - - - 5.8452 1 221125_WJC_METTL3_EV_vs_WT_F02.24687.24687.2 4.91E-11 19/34 R.K[136.11]PLVIIAEDVDGEALSTL.V "sp|P10809|CH60_HUMAN,tr|A0A7I2V2X6|A0A7I2V2X6_HUMAN,tr|A0A7I2YQK6|A0A7I2YQK6_HUMAN,tr|A0A7I2V599|A0A7I2V599_HUMAN,tr|A0A7I2YQ71|A0A7I2YQ71_HUMAN,tr|A0A7I2V5M1|A0A7I2V5M1_HUMAN,tr|A0A7I2V5K3|A0A7I2V5K3_HUMAN,tr|A0A7I2V369|A0A7I2V369_HUMAN" 8 1890.0441 0.95 23307 24687 2 1890.045867 946.0293 "60 kDa heat shock protein, mitochondrial OS=Homo sapiens OX=9606 GN=HSPD1 PE=1 SV=2" 3.92 3946.8 - 1.78E+06 - - - 0.9296 - 3.777 0.673 - 1568.2 1 1 0 0.0018 18 0 0 0 1.41E+07 1.49E+07 - - - 7.2785 1 221125_WJC_METTL3_EV_vs_WT_F02.24688.24688.3 0.00746 19/52 K.KLSTDVDLIVEVLR.S sp|Q92615|LAR4B_HUMAN 1 1598.9243 1.12 23308 24688 3 1598.925796 533.9821 La-related protein 4B OS=Homo sapiens OX=9606 GN=LARP4B PE=1 SV=3 4.56 3946.9 - 1.67E+06 - - - 0.9212 - 3.06 0.431 - 549.9 1 2 0 0.0015 14 0 0 0 1.24E+07 1.11E+07 - - - 6.317 1 221125_WJC_METTL3_EV_vs_WT_F02.24693.24693.3 1.06E-05 13/48 R.FQQAVDAVEEFLR.R "sp|Q49A26|GLYR1_HUMAN,tr|K7EMM8|K7EMM8_HUMAN,tr|K7EQB2|K7EQB2_HUMAN" 3 1550.7729 -1 23313 24693 3 1550.772938 517.9316 Putative oxidoreductase GLYR1 OS=Homo sapiens OX=9606 GN=GLYR1 PE=1 SV=4 4.14 3947.4 - 731653 - - - 0.0193 - 2.429 0.534 - 257.6 1 2 0 0 13 0 0 0 0.00E+00 0.00E+00 - - - 6.8998 1 221125_WJC_METTL3_EV_vs_WT_F02.24699.24699.3 1.20E-06 13/64 R.VFEVSLADLQNDEVAFR[166.11].K "sp|P61247|RS3A_HUMAN,tr|H0Y8L7|H0Y8L7_HUMAN,tr|D6RI02|D6RI02_HUMAN,tr|D6RED7|D6RED7_HUMAN,tr|D6RGE0|D6RGE0_HUMAN,tr|D6RAS7|D6RAS7_HUMAN,tr|D6RB09|D6RB09_HUMAN,tr|E9PFI5|E9PFI5_HUMAN,tr|D6RAT0|D6RAT0_HUMAN,tr|D6RG13|D6RG13_HUMAN" 10 1960.977 1.18 23318 24699 3 1960.975662 654.6663 40S ribosomal protein S3a OS=Homo sapiens OX=9606 GN=RPS3A PE=1 SV=2 3.92 3947.9 - 7.86E+06 - - - -0.6706 - 2.845 0.547 - 285.3 1 2 0 -0.0013 17 0 0 0 2.99E+07 2.54E+07 - - - 7.2796 0.99 221125_WJC_METTL3_EV_vs_WT_F02.24700.24700.2 4.29E-06 24-Nov K.STSESFIQHIVSL.V "sp|Q9NYF8|BCLF1_HUMAN,tr|E9PKI6|E9PKI6_HUMAN,tr|A0A1W2PQ43|A0A1W2PQ43_HUMAN,tr|E9PK91|E9PK91_HUMAN,tr|E9PJA7|E9PJA7_HUMAN,tr|E9PK09|E9PK09_HUMAN,tr|E9PQN2|E9PQN2_HUMAN" 7 1446.7355 - 23319 24700 2 1446.734475 724.375 Bcl-2-associated transcription factor 1 OS=Homo sapiens OX=9606 GN=BCLAF1 PE=1 SV=2 5.22 3948 - 7.14E+06 - - - -0.6802 - 2.161 0.461 - 315.2 1 1 0 -0.001 13 0 0 0 - - - - - 4.4233 1 221125_WJC_METTL3_EV_vs_WT_F02.24701.24701.2 2.21E-13 17/34 R.KPLVIIAEDVDGEALSTL.V "sp|P10809|CH60_HUMAN,tr|A0A7I2V2X6|A0A7I2V2X6_HUMAN,tr|A0A7I2YQK6|A0A7I2YQK6_HUMAN,tr|A0A7I2V599|A0A7I2V599_HUMAN,tr|A0A7I2YQ71|A0A7I2YQ71_HUMAN,tr|A0A7I2V5M1|A0A7I2V5M1_HUMAN,tr|A0A7I2V5K3|A0A7I2V5K3_HUMAN,tr|A0A7I2V369|A0A7I2V369_HUMAN" 8 1882.0299 0.95 23320 24701 2 1882.03217 942.0222 "60 kDa heat shock protein, mitochondrial OS=Homo sapiens OX=9606 GN=HSPD1 PE=1 SV=2" 3.92 3948 - 4.41E+06 - - - 1.2008 - 3.566 0.675 - 1089.3 1 1 0 0.0023 18 0 0 0 1.41E+07 1.49E+07 - - - 7.1517 0.9996 221125_WJC_METTL3_EV_vs_WT_F02.24702.24702.3 0.00915 16/52 K.K[136.11]LSTDVDLIVEVLR[166.11].S sp|Q92615|LAR4B_HUMAN 1 1616.9468 1.12 23321 24702 3 1616.946434 539.9895 La-related protein 4B OS=Homo sapiens OX=9606 GN=LARP4B PE=1 SV=3 4.56 3948.1 - 3.99E+06 - - - -0.222 - 2.871 0.246 - 363.2 1 2 0 -0.0004 14 0 0 0 1.24E+07 1.11E+07 - - - 4.0854 1 221125_WJC_METTL3_EV_vs_WT_F02.24703.24703.2 2.20E-13 18/32 K.EYGGLDVLVNNAGIAFK.V "sp|P16152|CBR1_HUMAN,tr|E9PQ63|E9PQ63_HUMAN,tr|A8MTM1|A8MTM1_HUMAN" 3 1778.9203 -1 23322 24703 2 1778.92224 890.4674 Carbonyl reductase [NADPH] 1 OS=Homo sapiens OX=9606 GN=CBR1 PE=1 SV=3 4.37 3948.1 - 3.78E+06 - - - 1.0905 - 3.203 0.649 - 1233.8 1 2 0 0.0019 17 0 0 0 0.00E+00 0.00E+00 - - - 6.6959 1 221125_WJC_METTL3_EV_vs_WT_F02.24705.24705.2 3.63E-08 14/32 K.EYGGLDVLVNNAGIAFK[136.11].V "sp|P16152|CBR1_HUMAN,tr|E9PQ63|E9PQ63_HUMAN,tr|A8MTM1|A8MTM1_HUMAN" 3 1786.9345 -1 23324 24705 2 1786.936507 894.4745 Carbonyl reductase [NADPH] 1 OS=Homo sapiens OX=9606 GN=CBR1 PE=1 SV=3 4.37 3948.3 - 2.97E+06 - - - 1.1232 - 2.759 0.629 - 540.9 1 2 0 0.002 17 0 0 0 0.00E+00 0.00E+00 - - - 6.1813 0.9797 221125_WJC_METTL3_EV_vs_WT_F02.24707.24707.3 0.253 Nov-60 K.K[136.11]LSGLNAFDIAEELVK[136.11].T "sp|O95983|MBD3_HUMAN,tr|A0A087X1H1|A0A087X1H1_HUMAN,tr|K7EIE8|K7EIE8_HUMAN,tr|A0A087WT34|A0A087WT34_HUMAN,tr|A0A0A0MTS6|A0A0A0MTS6_HUMAN" 5 1761.9848 2.45 23326 24707 3 1761.984101 588.3355 Methyl-CpG-binding domain protein 3 OS=Homo sapiens OX=9606 GN=MBD3 PE=1 SV=1 4.68 3948.4 - 2.67E+06 - - - -0.3689 - 1.798 0.12 - 132.9 1 2 0 -0.0007 16 0 0 0 2.89E+07 1.18E+07 - - - 1.383 0.9977 221125_WJC_METTL3_EV_vs_WT_F02.24708.24708.3 0.0271 Jul-64 K.EYGGLDVLVNNAGIAFK.V "sp|P16152|CBR1_HUMAN,tr|E9PQ63|E9PQ63_HUMAN,tr|A8MTM1|A8MTM1_HUMAN" 3 1778.9203 -1 23327 24708 3 1778.92256 593.9807 Carbonyl reductase [NADPH] 1 OS=Homo sapiens OX=9606 GN=CBR1 PE=1 SV=3 4.37 3948.4 - 2.55E+06 - - - 1.2704 - 1.784 0.271 - 70.8 2 2 0 0.0023 17 0 0 0 0.00E+00 0.00E+00 - - - 2.8838 1 221125_WJC_METTL3_EV_vs_WT_F02.24710.24710.3 4.16E-07 15/56 R.DFIHTASISFLTPLR.N "sp|Q9NR46|SHLB2_HUMAN,tr|B7ZC39|B7ZC39_HUMAN,tr|B7ZC38|B7ZC38_HUMAN" 3 1716.9199 1.41 23329 24710 3 1716.921271 573.3139 Endophilin-B2 OS=Homo sapiens OX=9606 GN=SH3GLB2 PE=1 SV=1 6.74 3948.5 - 1.51E+06 - - - 0.795 - 2.668 0.534 - 303 1 2 0 0.0014 15 0 0 0 5.35E+06 3.80E+06 - - - 7.0538 1 221125_WJC_METTL3_EV_vs_WT_F02.24714.24714.2 2.67E-10 15/30 K.NYLNFVSPLPDIVGQK[136.11].S sp|Q9Y2X9|ZN281_HUMAN 1 1810.9709 -1 23333 24714 2 1810.975226 906.4927 Zinc finger protein 281 OS=Homo sapiens OX=9606 GN=ZNF281 PE=1 SV=1 5.83 3948.9 - 1.14E+06 - - - 2.3965 - 2.546 0.601 - 572.6 1 2 0 0.0043 16 0 0 0 0.00E+00 0.00E+00 - - - 5.7762 1 221125_WJC_METTL3_EV_vs_WT_F02.24720.24720.3 8.07E-07 16/68 R.QATTIIADNIIFLSDQTK[136.11].E sp|Q04837|SSBP_HUMAN 1 1999.0717 1.38 23338 24720 3 1999.071764 667.3645 "Single-stranded DNA-binding protein, mitochondrial OS=Homo sapiens OX=9606 GN=SSBP1 PE=1 SV=1" 4.21 3949.5 - 1.49E+07 - - - 0.021 - 3.091 0.567 - 329.8 1 2 0 0 18 0 0 0 9.82E+07 7.10E+07 - - - 7.6715 0.9998 221125_WJC_METTL3_EV_vs_WT_F02.24722.24722.3 0.00363 Dec-60 R.ILDDDTIITTLENLKR.E "sp|Q14204|DYHC1_HUMAN,tr|A0A7P0T8N2|A0A7P0T8N2_HUMAN,tr|A0A7P0T9C4|A0A7P0T9C4_HUMAN,tr|A0A7P0TBJ7|A0A7P0TBJ7_HUMAN,tr|A0A7P0T9K2|A0A7P0T9K2_HUMAN,tr|A0A2R8Y706|A0A2R8Y706_HUMAN,tr|A0A7P0T916|A0A7P0T916_HUMAN,tr|A0A7P0TB75|A0A7P0TB75_HUMAN,tr|A0A7P0TAF3|A0A7P0TAF3_HUMAN,tr|A0A7P0TAW9|A0A7P0TAW9_HUMAN,tr|A0A7P0TA13|A0A7P0TA13_HUMAN,tr|A0A7P0T7V5|A0A7P0T7V5_HUMAN,tr|A0A7P0T9R4|A0A7P0T9R4_HUMAN,tr|A0A2R8Y5T0|A0A2R8Y5T0_HUMAN,tr|A0A2R8Y6H2|A0A2R8Y6H2_HUMAN" 15 1872.0204 0.57 23340 24722 3 1872.021574 625.0141 Cytoplasmic dynein 1 heavy chain 1 OS=Homo sapiens OX=9606 GN=DYNC1H1 PE=1 SV=5 4.23 3949.6 - 2.88E+06 - - - 0.6229 - 1.885 0.384 - 164.9 1 2 0 0.0012 16 0 0 0 6.56E+06 1.15E+07 - - - 4.4475 0.9981 221125_WJC_METTL3_EV_vs_WT_F02.24723.24723.3 0.000981 26/96 R.HLLPTSGAAATAAAAAAAAAAVTAA.S "sp|Q9BWF3|RBM4_HUMAN,tr|E9PB51|E9PB51_HUMAN" 2 2090.112 - 23341 24723 3 2090.112544 697.7113 RNA-binding protein 4 OS=Homo sapiens OX=9606 GN=RBM4 PE=1 SV=1 6.74 3949.6 - 2.65E+06 - - - 0.2521 - 4.134 0.487 - 725.7 1 1 0 0.0005 25 0 0 0 - - - - - 7.2346 0.9998 221125_WJC_METTL3_EV_vs_WT_F02.24724.24724.3 7.10E-07 13/64 R.FDLGLEDVLIPHVDAGK[136.11].G sp|O60476|MA1A2_HUMAN 1 1844.9764 1.34 23342 24724 3 1844.976907 615.9994 "Mannosyl-oligosaccharide 1,2-alpha-mannosidase IB OS=Homo sapiens OX=9606 GN=MAN1A2 PE=1 SV=1" 4.22 3949.7 - 2.53E+06 - - - 0.2938 - 2.45 0.33 - 149.5 1 2 0 0.0005 17 0 0 0 8.78E+06 6.55E+06 - - - 4.4828 1 221125_WJC_METTL3_EV_vs_WT_F02.24727.24727.2 1.62E-08 19/28 K.IESEGLLSLTTQLVK.E "sp|Q92552|RT27_HUMAN,tr|G5EA06|G5EA06_HUMAN" 2 1629.9189 -1 23345 24727 2 1629.920186 815.9667 "28S ribosomal protein S27, mitochondrial OS=Homo sapiens OX=9606 GN=MRPS27 PE=1 SV=3" 4.53 3949.9 - 2.37E+06 - - - 0.7872 - 3.816 0.626 - 1429.9 1 2 0 0.0013 15 0 0 0 0.00E+00 0.00E+00 - - - 6.9567 1 221125_WJC_METTL3_EV_vs_WT_F02.24728.24728.2 3.55E-08 16/28 K.IESEGLLSLTTQLVK[136.11].E "sp|Q92552|RT27_HUMAN,tr|G5EA06|G5EA06_HUMAN" 2 1637.9331 -1 23346 24728 2 1637.935377 819.9738 "28S ribosomal protein S27, mitochondrial OS=Homo sapiens OX=9606 GN=MRPS27 PE=1 SV=3" 4.53 3950 - 2.33E+06 - - - 1.3883 - 3.361 0.602 - 947.1 1 2 0 0.0023 15 0 0 0 0.00E+00 0.00E+00 - - - 6.467 0.9999 221125_WJC_METTL3_EV_vs_WT_F02.24731.24731.3 0.000183 Dec-56 R.DFIHTASISFLTPLR[166.11].N "sp|Q9NR46|SHLB2_HUMAN,tr|B7ZC39|B7ZC39_HUMAN,tr|B7ZC38|B7ZC38_HUMAN" 3 1726.9282 -1 23349 24731 3 1726.931879 576.65 Endophilin-B2 OS=Homo sapiens OX=9606 GN=SH3GLB2 PE=1 SV=1 6.74 3950.2 - 1.67E+06 - - - 2.1443 - 2.27 0.474 - 119.8 1 2 0 0.0037 15 0 0 0 0.00E+00 0.00E+00 - - - 5.9627 0.9997 221125_WJC_METTL3_EV_vs_WT_F02.24735.24735.3 0.000158 15/56 K.IESEGLLSLTTQLVK[136.11].E "sp|Q92552|RT27_HUMAN,tr|G5EA06|G5EA06_HUMAN" 2 1637.9331 1.29 23353 24735 3 1637.933314 546.985 "28S ribosomal protein S27, mitochondrial OS=Homo sapiens OX=9606 GN=MRPS27 PE=1 SV=3" 4.53 3950.6 - 1.26E+06 - - - 0.1288 - 2.303 0.308 - 275.2 1 2 0 0.0002 15 0 0 0 5.22E+06 4.05E+06 - - - 4.1506 0.9995 221125_WJC_METTL3_EV_vs_WT_F02.24740.24740.3 3.65E-08 16/52 K.TYLFLQEYLDAIKK.F sp|P29508|SPB3_HUMAN 1 1743.9447 3.57 23357 24740 3 1744.949953 582.3222 Serpin B3 OS=Homo sapiens OX=9606 GN=SERPINB3 PE=1 SV=2 5.73 3951.1 - 9.21E+06 - - - 576.411 - 3.029 0.575 - 253.3 1 2 0 1.0052 14 0 0 0 3.45E+07 9.66E+06 - - - 7.6174 1 221125_WJC_METTL3_EV_vs_WT_F02.24741.24741.3 9.07E-10 22/88 R.GFGFVTFENIDDAKDAMMAMNGK.S "sp|Q14011|CIRBP_HUMAN,tr|K7ER40|K7ER40_HUMAN,tr|K7ENX8|K7ENX8_HUMAN,tr|K7EJV1|K7EJV1_HUMAN,tr|K7EJV5|K7EJV5_HUMAN,tr|K7ELT6|K7ELT6_HUMAN,tr|K7EMY9|K7EMY9_HUMAN,tr|K7ELV6|K7ELV6_HUMAN,tr|K7EQR7|K7EQR7_HUMAN,tr|K7EPM4|K7EPM4_HUMAN,tr|D6W5Y5|D6W5Y5_HUMAN" 11 2508.1124 -1 23358 24741 3 2508.112643 837.0447 Cold-inducible RNA-binding protein OS=Homo sapiens OX=9606 GN=CIRBP PE=1 SV=1 4.23 3951.2 - 8.54E+06 - - - 0.1156 - 4.092 0.661 - 415 1 2 1 0.0003 23 0 0 0 0.00E+00 0.00E+00 - - - 9.2149 1 221125_WJC_METTL3_EV_vs_WT_F02.24742.24742.3 5.53E-08 19/64 K.ITGEAFVQFASQELAEK.A sp|P52597|HNRPF_HUMAN 1 1866.9363 0.8 23359 24742 3 1866.939975 623.3194 Heterogeneous nuclear ribonucleoprotein F OS=Homo sapiens OX=9606 GN=HNRNPF PE=1 SV=3 4.25 3951.2 - 4.22E+06 - - - 1.9449 - 3.882 0.564 - 608.9 1 2 0 0.0036 17 0 0 0 3.89E+07 4.83E+07 - - - 8.2536 1 221125_WJC_METTL3_EV_vs_WT_F02.24746.24746.2 8.28E-15 25/36 R.GWFDAEGQALDGVSISDLK.S "sp|P27694|RFA1_HUMAN,tr|I3L4R8|I3L4R8_HUMAN" 2 2006.9585 -1 23363 24746 2 2006.959849 1004.4865 Replication protein A 70 kDa DNA-binding subunit OS=Homo sapiens OX=9606 GN=RPA1 PE=1 SV=2 3.84 3951.4 - 3.52E+06 - - - 0.6542 - 4.099 0.755 - 1835.5 1 2 0 0.0013 19 0 0 0 0.00E+00 0.00E+00 - - - 8.0854 1 221125_WJC_METTL3_EV_vs_WT_F02.24747.24747.2 3.61E-16 21/36 R.GWFDAEGQALDGVSISDLK[136.11].S "sp|P27694|RFA1_HUMAN,tr|I3L4R8|I3L4R8_HUMAN" 2 2014.9727 -1 23364 24747 2 2014.972075 1008.4936 Replication protein A 70 kDa DNA-binding subunit OS=Homo sapiens OX=9606 GN=RPA1 PE=1 SV=2 3.84 3951.5 - 3.12E+06 - - - -0.328 - 3.979 0.743 - 1181.7 1 2 0 -0.0007 19 0 0 0 0.00E+00 0.00E+00 - - - 7.9239 1 221125_WJC_METTL3_EV_vs_WT_F02.24748.24748.2 4.62E-08 22/32 K.ITGEAFVQFASQELAEK.A sp|P52597|HNRPF_HUMAN 1 1866.9363 0.82 23365 24748 2 1866.937926 934.4754 Heterogeneous nuclear ribonucleoprotein F OS=Homo sapiens OX=9606 GN=HNRNPF PE=1 SV=3 4.25 3951.6 - 2.66E+06 - - - 0.8474 - 4.102 0.598 - 2140.8 1 2 0 0.0016 17 0 0 0 3.79E+07 4.62E+07 - - - 6.9275 0.9999 221125_WJC_METTL3_EV_vs_WT_F02.24752.24752.3 9.69E-06 14/56 K.IESEGLLSLTTQLVK.E "sp|Q92552|RT27_HUMAN,tr|G5EA06|G5EA06_HUMAN" 2 1629.9189 1.29 23369 24752 3 1629.920044 544.3136 "28S ribosomal protein S27, mitochondrial OS=Homo sapiens OX=9606 GN=MRPS27 PE=1 SV=3" 4.53 3951.9 - 2.10E+06 - - - 0.7 - 2.152 0.453 - 219.7 1 2 0 0.0011 15 0 0 0 5.22E+06 4.05E+06 - - - 5.59 0.9999 221125_WJC_METTL3_EV_vs_WT_F02.24753.24753.2 1.07E-12 17/28 R.EFNEEGALSVLQQFK.E "sp|O43390|HNRPR_HUMAN,tr|A0A6Q8PH35|A0A6Q8PH35_HUMAN" 2 1737.8574 -1 23370 24753 2 1737.859269 869.936 Heterogeneous nuclear ribonucleoprotein R OS=Homo sapiens OX=9606 GN=HNRNPR PE=1 SV=1 4.25 3952 - 2.04E+06 - - - 1.095 - 3.057 0.45 - 1134.4 1 2 0 0.0019 15 0 0 0 0.00E+00 0.00E+00 - - - 5.1114 0.9999 221125_WJC_METTL3_EV_vs_WT_F02.24755.24755.3 0.000372 17/60 K.EIPAWVPFDPAAQITK.Q "sp|P25311|ZA2G_HUMAN,tr|C9JEV0|C9JEV0_HUMAN" 2 1781.9352 3.47 23372 24755 3 1781.938334 594.9857 Zinc-alpha-2-glycoprotein OS=Homo sapiens OX=9606 GN=AZGP1 PE=1 SV=2 4.37 3952.1 - 1.65E+06 - - - 1.7464 - 2.498 0.478 - 346.8 1 2 0 0.0031 16 0 0 0 1.21E+07 3.49E+06 - - - 6.2174 1 221125_WJC_METTL3_EV_vs_WT_F02.24759.24759.3 1.93E-05 23/92 K.GLFYFDNSFRPVPLEQTYVGITEK.K "sp|O75643|U520_HUMAN,tr|A0A494C1A5|A0A494C1A5_HUMAN" 2 2819.417 -1 23375 24759 3 2819.422203 940.813 U5 small nuclear ribonucleoprotein 200 kDa helicase OS=Homo sapiens OX=9606 GN=SNRNP200 PE=1 SV=2 4.68 3952.5 - 2.93E+06 - - - 1.8337 - 3.972 0.505 - 572.2 1 2 0 0.0052 24 0 0 0 0.00E+00 0.00E+00 - - - 7.3723 1 221125_WJC_METTL3_EV_vs_WT_F02.24762.24762.3 1.90E-10 15/72 R.GWFDAEGQALDGVSISDLK.S "sp|P27694|RFA1_HUMAN,tr|I3L4R8|I3L4R8_HUMAN" 2 2006.9585 -1 23378 24762 3 2006.957242 669.9935 Replication protein A 70 kDa DNA-binding subunit OS=Homo sapiens OX=9606 GN=RPA1 PE=1 SV=2 3.84 3952.7 - 4.91E+06 - - - -0.6448 - 3.176 0.66 - 277 1 2 0 -0.0013 19 0 0 0 0.00E+00 0.00E+00 - - - 8.7371 0.9971 221125_WJC_METTL3_EV_vs_WT_F02.24766.24766.3 0.00227 19/68 R.PIK[136.11]PSPPYFGLLLASVGR[166.11].L "sp|P17812|PYRG1_HUMAN,tr|B4E1E0|B4E1E0_HUMAN,tr|A0A3B3IRI2|A0A3B3IRI2_HUMAN" 3 1929.1207 0.7 23382 24766 3 1929.118603 644.0475 CTP synthase 1 OS=Homo sapiens OX=9606 GN=CTPS1 PE=1 SV=2 10.01 3953 - 2.42E+06 - - - -1.0741 - 3.309 0.461 - 404.2 1 1 0 -0.0021 18 0 0 0 4.95E+06 7.10E+06 - - - 6.6589 1 221125_WJC_METTL3_EV_vs_WT_F02.24770.24770.3 5.00E-15 30/92 R.IGGGIGFGGLEAMNSMGGFGGVGR.M "sp|Q9P2K5|MYEF2_HUMAN,tr|A0A0A0MR39|A0A0A0MR39_HUMAN,tr|A0A0C4DGV1|A0A0C4DGV1_HUMAN,tr|A0A087WUT0|A0A087WUT0_HUMAN,tr|A0A0A0MQW0|A0A0A0MQW0_HUMAN" 5 2197.0408 -1 23386 24770 3 2197.038145 733.3542 Myelin expression factor 2 OS=Homo sapiens OX=9606 GN=MYEF2 PE=1 SV=3 6 3953.3 - 1.92E+06 - - - -1.228 - 4.679 0.7 - 647.6 1 2 0 -0.0027 24 0 0 0 0.00E+00 0.00E+00 - - - 9.9275 1 221125_WJC_METTL3_EV_vs_WT_F02.24771.24771.2 0.0221 17/30 K.ITISPLQELTLYNPER[166.11].T sp|O00425|IF2B3_HUMAN 1 1896.0232 -1 23387 24771 2 1896.0217 949.0189 Insulin-like growth factor 2 mRNA-binding protein 3 OS=Homo sapiens OX=9606 GN=IGF2BP3 PE=1 SV=2 4.53 3953.5 - 1.85E+06 - - - -0.7906 - 3.248 0.515 - 1001.8 1 2 0 -0.0015 16 0 0 0 0.00E+00 0.00E+00 - - - 5.7406 1 221125_WJC_METTL3_EV_vs_WT_F02.24772.24772.3 7.67E-17 25/108 K.NIILEEGK[136.11]EILVGDVGQTVDDPYATFVK[136.11].M "sp|P23528|COF1_HUMAN,tr|E9PP50|E9PP50_HUMAN,tr|G3V1A4|G3V1A4_HUMAN,tr|E9PQB7|E9PQB7_HUMAN,tr|E9PK25|E9PK25_HUMAN,tr|E9PLJ3|E9PLJ3_HUMAN,tr|E9PS23|E9PS23_HUMAN" 7 3077.6143 -1 23388 24772 3 3077.608729 1026.8787 Cofilin-1 OS=Homo sapiens OX=9606 GN=CFL1 PE=1 SV=3 4.02 3953.6 - 1.55E+06 - - - -1.8261 - 4.896 0.719 - 635.3 1 2 1 -0.0056 28 0 0 0 0.00E+00 0.00E+00 - - - 10.209 1 221125_WJC_METTL3_EV_vs_WT_F02.24773.24773.2 5.38E-11 15/32 K.EGETYFDVVAVVDPVTR[166.11].E sp|Q9NYU2|UGGG1_HUMAN 1 1904.9395 -1 23389 24773 2 1904.941004 953.477 UDP-glucose:glycoprotein glucosyltransferase 1 OS=Homo sapiens OX=9606 GN=UGGT1 PE=1 SV=3 3.92 3953.7 - 1.46E+06 - - - 0.7743 - 2.988 0.649 - 397.3 1 2 0 0.0015 17 0 0 0 0.00E+00 0.00E+00 - - - 6.5252 0.9989 221125_WJC_METTL3_EV_vs_WT_F02.24775.24775.3 0.000475 Nov-80 K.VLGTEDLYDYIDKYNIELDPR.F "sp|P68400|CSK21_HUMAN,tr|A0A2R8YFU2|A0A2R8YFU2_HUMAN,tr|A0A2R8YD58|A0A2R8YD58_HUMAN,tr|A0A2R8YF43|A0A2R8YF43_HUMAN,tr|A0A2R8Y5A0|A0A2R8Y5A0_HUMAN,tr|A0A2R8YDP2|A0A2R8YDP2_HUMAN,tr|E7EU96|E7EU96_HUMAN" 7 2543.2432 -1 23391 24775 3 2543.241431 848.755 Casein kinase II subunit alpha OS=Homo sapiens OX=9606 GN=CSNK2A1 PE=1 SV=1 3.96 3953.9 - 1.37E+06 - - - -0.6763 - 1.88 0.391 - 54.8 1 2 1 -0.0017 21 0 0 0 0.00E+00 0.00E+00 - - - 4.4122 0.9999 221125_WJC_METTL3_EV_vs_WT_F02.24780.24780.2 9.48E-08 28-Nov R.EFNEEGALSVLQQFK[136.11].E "sp|O43390|HNRPR_HUMAN,tr|A0A6Q8PH35|A0A6Q8PH35_HUMAN" 2 1745.8716 -1 23395 24780 2 1745.869579 873.9431 Heterogeneous nuclear ribonucleoprotein R OS=Homo sapiens OX=9606 GN=HNRNPR PE=1 SV=1 4.25 3954.4 - 949851 - - - -1.1381 - 2.241 0.548 - 350.7 1 2 0 -0.002 15 0 0 0 0.00E+00 0.00E+00 - - - 5.0718 1 221125_WJC_METTL3_EV_vs_WT_F02.24782.24782.2 8.96E-09 18/32 R.GPGLLESPSIFNFTADR.L sp|Q92615|LAR4B_HUMAN 1 1819.9105 1.3 23397 24782 2 1819.907934 910.9625 La-related protein 4B OS=Homo sapiens OX=9606 GN=LARP4B PE=1 SV=3 4.37 3954.5 - 2.33E+07 - - - -1.3902 - 3.521 0.648 - 960.4 1 2 0 -0.0025 17 0 0 0 1.11E+08 8.54E+07 - - - 6.921 1 221125_WJC_METTL3_EV_vs_WT_F02.24783.24783.2 1.70E-11 20/32 R.GPGLLESPSIFNFTADR[166.11].L sp|Q92615|LAR4B_HUMAN 1 1829.9187 1.3 23398 24783 2 1829.91467 915.9666 La-related protein 4B OS=Homo sapiens OX=9606 GN=LARP4B PE=1 SV=3 4.37 3954.6 - 2.03E+07 - - - -2.2209 - 3.831 0.647 - 1223 1 2 0 -0.0041 17 0 0 0 1.11E+08 8.54E+07 - - - 7.1206 1 221125_WJC_METTL3_EV_vs_WT_F02.24785.24785.3 5.54E-10 16/64 R.GPGLLESPSIFNFTADR.L sp|Q92615|LAR4B_HUMAN 1 1819.9105 1.52 23400 24785 3 1819.909167 607.6441 La-related protein 4B OS=Homo sapiens OX=9606 GN=LARP4B PE=1 SV=3 4.37 3954.7 - 9.99E+06 - - - -0.7127 - 2.903 0.631 - 445 1 2 0 -0.0013 17 0 0 0 3.80E+07 2.49E+07 - - - 8.2671 1 221125_WJC_METTL3_EV_vs_WT_F02.24786.24786.2 6.27E-08 17/30 R.QLLQANPILEAFGNAK[136.11].T "sp|Q7Z406|MYH14_HUMAN,sp|Q9UKX3|MYH13_HUMAN,sp|P35749|MYH11_HUMAN,sp|P35579|MYH9_HUMAN,tr|A0A2R8Y4C3|A0A2R8Y4C3_HUMAN,tr|M0QY43|M0QY43_HUMAN,tr|A0A494C024|A0A494C024_HUMAN" 7 1733.9556 1.09 23401 24786 2 1733.953292 867.9851 Myosin-14 OS=Homo sapiens OX=9606 GN=MYH14 PE=1 SV=2 6 3954.7 - 8.04E+06 - - - -1.3138 - 3.234 0.58 - 809.5 1 2 0 -0.0023 16 0 0 0 4.70E+07 4.31E+07 - - - 6.2098 1 221125_WJC_METTL3_EV_vs_WT_F02.24787.24787.2 1.16E-06 17/30 R.QLLQANPILEAFGNAK.T "sp|Q7Z406|MYH14_HUMAN,sp|Q9UKX3|MYH13_HUMAN,sp|P35749|MYH11_HUMAN,sp|P35579|MYH9_HUMAN,tr|A0A2R8Y4C3|A0A2R8Y4C3_HUMAN,tr|M0QY43|M0QY43_HUMAN,tr|A0A494C024|A0A494C024_HUMAN" 7 1725.9414 1.09 23402 24787 2 1725.939782 863.978 Myosin-14 OS=Homo sapiens OX=9606 GN=MYH14 PE=1 SV=2 6 3954.8 - 7.24E+06 - - - -0.9201 - 3.58 0.608 - 971.7 1 2 0 -0.0016 16 0 0 0 4.72E+07 4.31E+07 - - - 6.6667 0.9998 221125_WJC_METTL3_EV_vs_WT_F02.24788.24788.2 0.00139 20-Oct R.DLEEFFSTVGK[136.11].V "sp|Q14498|RBM39_HUMAN,tr|Q5QP22|Q5QP22_HUMAN,tr|H0Y4X3|H0Y4X3_HUMAN,tr|A0A0U1RQH7|A0A0U1RQH7_HUMAN,tr|Q5QP23|Q5QP23_HUMAN,tr|G3XAC6|G3XAC6_HUMAN" 6 1278.6223 0.9 23403 24788 2 1278.620755 640.3184 RNA-binding protein 39 OS=Homo sapiens OX=9606 GN=RBM39 PE=1 SV=2 4.14 3954.8 - 6.07E+06 - - - -1.2349 - 2.265 0.476 - 258.8 1 2 0 -0.0016 11 0 0 0 1.52E+07 1.68E+07 - - - 4.768 1 221125_WJC_METTL3_EV_vs_WT_F02.24790.24790.2 7.13E-12 22/38 R.IIGLDQVAGMSETALPGAFK.T sp|P35579|MYH9_HUMAN 1 2017.0554 -1 23405 24790 2 2017.054457 1009.535 Myosin-9 OS=Homo sapiens OX=9606 GN=MYH9 PE=1 SV=4 4.37 3954.9 - 3.46E+06 - - - -0.4745 - 3.925 0.68 - 797 1 2 0 -0.001 20 0 0 0 0.00E+00 0.00E+00 - - - 7.4249 1 221125_WJC_METTL3_EV_vs_WT_F02.24799.24799.3 7.05E-08 24/80 R.FVTHVSDWGALATISTLEAVR.G "sp|O75629|CREG1_HUMAN,tr|A0A3B3IRL2|A0A3B3IRL2_HUMAN" 2 2272.1852 -1 23414 24799 3 2272.189891 758.4023 Protein CREG1 OS=Homo sapiens OX=9606 GN=CREG1 PE=1 SV=1 5.32 3955.9 - 1.05E+06 - - - 2.0725 - 4.139 0.516 - 675.9 1 2 0 0.0047 21 0 0 0 0.00E+00 0.00E+00 - - - 7.6971 0.9974 221125_WJC_METTL3_EV_vs_WT_F02.24801.24801.3 5.09E-07 18/72 G.AGPPPIQDGEFTFLLPAGR.K "sp|Q13445|TMED1_HUMAN,tr|K7ER03|K7ER03_HUMAN,tr|K7ERK5|K7ERK5_HUMAN,tr|K7ES06|K7ES06_HUMAN,tr|K7EQ63|K7EQ63_HUMAN" 5 1982.0262 -1 23415 24801 3 1982.029891 661.6827 Transmembrane emp24 domain-containing protein 1 OS=Homo sapiens OX=9606 GN=TMED1 PE=1 SV=1 4.37 3956.1 - 836287 - - - 1.8814 - 3.335 0.55 - 308.1 1 1 0 0.0037 19 0 0 0 0.00E+00 0.00E+00 - - - 7.6301 0.9896 221125_WJC_METTL3_EV_vs_WT_F02.24802.24802.3 0.0847 Sep-76 R.QTAVGLELLAEAGNYSALQR.M "sp|Q9BZE3|BARH1_HUMAN,sp|Q9NY43|BARH2_HUMAN" 2 2103.096 -1 23416 24802 3 2103.093473 702.0393 BarH-like 1 homeobox protein OS=Homo sapiens OX=9606 GN=BARHL1 PE=2 SV=1 4.53 3956.2 - 310051 - - - -1.2173 - 1.73 0.177 - 59.8 1 2 0 -0.0026 20 0 0 0 0.00E+00 0.00E+00 - - - 1.8424 1 221125_WJC_METTL3_EV_vs_WT_F02.24812.24812.2 5.11E-08 17/34 K.VEPAVSSVVNSIQVLTSK[136.11].A "sp|Q9P2E9|RRBP1_HUMAN,tr|A2A2S5|A2A2S5_HUMAN" 2 1864.0397 0.58 23426 24812 2 1864.039031 933.0271 Ribosome-binding protein 1 OS=Homo sapiens OX=9606 GN=RRBP1 PE=1 SV=5 5.97 3957.2 - 409599 - - - -0.3557 - 3.41 0.622 - 712.3 1 2 0 -0.0007 18 0 0 0 3.03E+06 5.23E+06 - - - 6.6508 1 221125_WJC_METTL3_EV_vs_WT_F02.24816.24816.3 6.84E-11 17/64 R.GPGLLESPSIFNFTADR[166.11].L sp|Q92615|LAR4B_HUMAN 1 1829.9187 1.52 23429 24816 3 1829.916483 610.9802 La-related protein 4B OS=Homo sapiens OX=9606 GN=LARP4B PE=1 SV=3 4.37 3957.7 - 4.81E+06 - - - -1.2301 - 3.131 0.577 - 478.3 1 2 0 -0.0023 17 0 0 0 3.80E+07 2.49E+07 - - - 7.8558 1 221125_WJC_METTL3_EV_vs_WT_F02.24823.24823.3 5.90E-12 25/76 R.LGEIQHMSQAC[160.03]LLSLLPVPR.D "sp|Q9ULV3|CIZ1_HUMAN,tr|Q5SYW2|Q5SYW2_HUMAN,tr|F5H2X7|F5H2X7_HUMAN,tr|H0Y5D5|H0Y5D5_HUMAN,tr|A0A0U1RQR2|A0A0U1RQR2_HUMAN,tr|A0A494C0L7|A0A494C0L7_HUMAN,tr|Q9BTG3|Q9BTG3_HUMAN" 7 2261.2024 2.85 23436 24823 3 2261.203056 754.7414 Cip1-interacting zinc finger protein OS=Homo sapiens OX=9606 GN=CIZ1 PE=1 SV=2 6.74 3958.1 - 2.56E+06 - - - 0.2773 - 3.985 0.684 - 712.2 1 2 0 0.0006 20 0 0 0 1.28E+07 4.49E+06 - - - 9.5198 0.9639 221125_WJC_METTL3_EV_vs_WT_F02.24824.24824.3 0.0348 Dec-76 K.TLLEIPPPKPPAPLLHFLPS.A "sp|Q8WXI9|P66B_HUMAN,tr|A0A0U1RRM1|A0A0U1RRM1_HUMAN,tr|A0A0U1RR30|A0A0U1RR30_HUMAN" 3 2176.266 2.16 23437 24824 3 2176.265217 726.4293 Transcriptional repressor p66-beta OS=Homo sapiens OX=9606 GN=GATAD2B PE=1 SV=1 6.41 3958.2 - 1.66E+06 - - - -0.3593 - 2.436 0.304 - 113.4 1 1 0 -0.0008 20 0 0 0 8.67E+06 4.01E+06 - - - 4.0891 1 221125_WJC_METTL3_EV_vs_WT_F02.24825.24825.3 7.87E-08 16/68 K.VEPAVSSVVNSIQVLTSK[136.11].A "sp|Q9P2E9|RRBP1_HUMAN,tr|A2A2S5|A2A2S5_HUMAN" 2 1864.0397 0.66 23438 24825 3 1864.037821 622.3538 Ribosome-binding protein 1 OS=Homo sapiens OX=9606 GN=RRBP1 PE=1 SV=5 5.97 3958.3 - 1.56E+06 - - - -1.0048 - 2.771 0.52 - 329 1 2 0 -0.0019 18 0 0 0 9.36E+06 1.42E+07 - - - 6.8749 1 221125_WJC_METTL3_EV_vs_WT_F02.24826.24826.3 7.61E-10 17/68 R.LLEPLVTQVTTLVNTNSK[136.11].G "sp|P35221|CTNA1_HUMAN,tr|E5RHV7|E5RHV7_HUMAN,tr|E5RJL0|E5RJL0_HUMAN,tr|E5RIE0|E5RIE0_HUMAN,tr|E5RIB1|E5RIB1_HUMAN,tr|E5RGY6|E5RGY6_HUMAN,tr|E5RG03|E5RG03_HUMAN,tr|E5RFM3|E5RFM3_HUMAN,tr|G3XAM7|G3XAM7_HUMAN" 9 1977.1238 -1 23439 24826 3 1977.125916 660.0485 Catenin alpha-1 OS=Homo sapiens OX=9606 GN=CTNNA1 PE=1 SV=1 6 3958.4 - 1.45E+06 - - - 1.0915 - 3.26 0.575 - 353.1 1 2 0 0.0022 18 0 0 0 0.00E+00 0.00E+00 - - - 7.8927 0.9997 221125_WJC_METTL3_EV_vs_WT_F02.24827.24827.2 9.09E-07 14/40 R.DIGEGNLSTAAAAALAAAAVK.A "sp|Q8TAQ2|SMRC2_HUMAN,tr|F8VXC8|F8VXC8_HUMAN" 2 1883.9953 -1 23440 24827 2 1883.993122 943.0049 SWI\SNF complex subunit SMARCC2 OS=Homo sapiens OX=9606 GN=SMARCC2 PE=1 SV=1 4.37 3958.5 - 1.41E+06 - - - -1.1327 - 2.394 0.385 - 280.3 1 2 0 -0.0021 21 0 0 0 0.00E+00 0.00E+00 - - - 4.0302 1 221125_WJC_METTL3_EV_vs_WT_F02.24829.24829.3 1.05E-05 22/52 K.ISIVEALTLLNNHK.L sp|Q9P032|NDUF4_HUMAN 1 1563.8984 1.36 23442 24829 3 1563.896761 522.3068 NADH dehydrogenase [ubiquinone] 1 alpha subcomplex assembly factor 4 OS=Homo sapiens OX=9606 GN=NDUFAF4 PE=1 SV=1 6.75 3958.8 - 1.13E+06 - - - -1.0749 - 3.382 0.479 - 688 1 2 0 -0.0017 14 0 0 0 5.46E+07 4.02E+07 - - - 7.118 0.9999 221125_WJC_METTL3_EV_vs_WT_F02.24830.24830.3 2.62E-06 21/52 K.ISIVEALTLLNNHK[136.11].L sp|Q9P032|NDUF4_HUMAN 1 1571.9126 1.36 23443 24830 3 1571.907228 524.9782 NADH dehydrogenase [ubiquinone] 1 alpha subcomplex assembly factor 4 OS=Homo sapiens OX=9606 GN=NDUFAF4 PE=1 SV=1 6.75 3958.9 - 1.08E+06 - - - -3.4442 - 3.433 0.459 - 669.4 1 2 0 -0.0054 14 0 0 0 5.46E+07 4.02E+07 - - - 6.9338 1 221125_WJC_METTL3_EV_vs_WT_F02.24839.24839.3 1.75E-09 25/76 R.K[136.11]LPIDVTEGEVISLGLPFGK[136.11].V "sp|P26599|PTBP1_HUMAN,tr|A0A6Q8PEX4|A0A6Q8PEX4_HUMAN,tr|A0A0U1RRM4|A0A0U1RRM4_HUMAN,tr|A6NLN1|A6NLN1_HUMAN,tr|K7EKJ7|K7EKJ7_HUMAN,tr|K7ELW5|K7ELW5_HUMAN,tr|K7ES59|K7ES59_HUMAN,tr|A0A7I2V4H6|A0A7I2V4H6_HUMAN,tr|A0A7I2V621|A0A7I2V621_HUMAN" 9 2127.2162 1.05 23450 24839 3 2127.21262 710.0793 Polypyrimidine tract-binding protein 1 OS=Homo sapiens OX=9606 GN=PTBP1 PE=1 SV=1 4.68 3960 - 4.43E+07 - - - -1.6867 - 3.249 0.663 - 580.7 1 2 0 -0.0036 20 0 0 0 2.10E+08 2.00E+08 - - - 8.7895 1 221125_WJC_METTL3_EV_vs_WT_F02.24840.24840.3 1.42E-07 19/68 K.SNLAYDIVQLPTGLTGIK[136.11].V "sp|P34932|HSP74_HUMAN,tr|A0A087WTS8|A0A087WTS8_HUMAN,tr|A0A087WYC1|A0A087WYC1_HUMAN" 3 1910.0604 0.11 23451 24840 3 1910.058073 637.6941 Heat shock 70 kDa protein 4 OS=Homo sapiens OX=9606 GN=HSPA4 PE=1 SV=4 5.55 3960 - 2.19E+07 - - - -1.2335 - 3.333 0.641 - 434.5 1 2 0 -0.0024 18 0 0 0 7.79E+06 7.29E+07 - - - 8.6836 1 221125_WJC_METTL3_EV_vs_WT_F02.24841.24841.3 9.24E-05 15/64 R.QAFTPSSTMMEVFLQEK.S "sp|Q14157|UBP2L_HUMAN,tr|F8W726|F8W726_HUMAN" 2 1972.9274 -1 23452 24841 3 1972.927278 658.6498 Ubiquitin-associated protein 2-like OS=Homo sapiens OX=9606 GN=UBAP2L PE=1 SV=2 4.53 3960.1 - 1.78E+07 - - - -0.0801 - 2.897 0.52 - 343.5 1 2 0 -0.0002 17 0 0 0 0.00E+00 0.00E+00 - - - 7.0246 1 221125_WJC_METTL3_EV_vs_WT_F02.24843.24843.2 7.87E-11 18/32 R.QAFTPSSTMMEVFLQEK.S "sp|Q14157|UBP2L_HUMAN,tr|F8W726|F8W726_HUMAN" 2 1972.9274 2.04 23454 24843 2 1972.926562 987.471 Ubiquitin-associated protein 2-like OS=Homo sapiens OX=9606 GN=UBAP2L PE=1 SV=2 4.53 3960.2 - 1.20E+07 - - - -0.443 - 3.707 0.693 - 1203.2 1 2 0 -0.0009 17 0 0 0 7.20E+07 3.52E+07 - - - 7.3805 1 221125_WJC_METTL3_EV_vs_WT_F02.24844.24844.2 6.12E-09 18/34 K.SNLAYDIVQLPTGLTGIK[136.11].V "sp|P34932|HSP74_HUMAN,tr|A0A087WTS8|A0A087WTS8_HUMAN,tr|A0A087WYC1|A0A087WYC1_HUMAN" 3 1910.0604 0.08 23455 24844 2 1910.058234 956.0375 Heat shock 70 kDa protein 4 OS=Homo sapiens OX=9606 GN=HSPA4 PE=1 SV=4 5.55 3960.2 - 1.09E+07 - - - -1.1492 - 3.598 0.666 - 789.1 1 2 0 -0.0022 18 0 0 0 4.28E+06 5.15E+07 - - - 7.1073 1 221125_WJC_METTL3_EV_vs_WT_F02.24845.24845.3 2.64E-09 14/64 R.QAFTPSSTMMEVFLQEK[136.11].S "sp|Q14157|UBP2L_HUMAN,tr|F8W726|F8W726_HUMAN" 2 1980.9416 2.02 23456 24845 3 1980.940784 661.3212 Ubiquitin-associated protein 2-like OS=Homo sapiens OX=9606 GN=UBAP2L PE=1 SV=2 4.53 3960.2 - 9.81E+06 - - - -0.4301 - 3.043 0.578 - 313.7 1 2 0 -0.0009 17 0 0 0 8.59E+07 4.25E+07 - - - 7.7953 1 221125_WJC_METTL3_EV_vs_WT_F02.24846.24846.2 2.47E-12 14/32 R.QAFTPSSTMMEVFLQEK[136.11].S "sp|Q14157|UBP2L_HUMAN,tr|F8W726|F8W726_HUMAN" 2 1980.9416 2.04 23457 24846 2 1980.938299 991.4781 Ubiquitin-associated protein 2-like OS=Homo sapiens OX=9606 GN=UBAP2L PE=1 SV=2 4.53 3960.3 - 7.35E+06 - - - -1.6846 - 3.111 0.687 - 541.6 1 2 0 -0.0033 17 0 0 0 7.20E+07 3.52E+07 - - - 6.9044 1 221125_WJC_METTL3_EV_vs_WT_F02.24851.24851.3 8.68E-06 15/64 K.NATNVEQSFMTMAAEIK[136.11].K "sp|P62820|RAB1A_HUMAN,tr|E7END7|E7END7_HUMAN" 2 1891.8899 -1 23462 24851 3 1891.887693 631.6373 Ras-related protein Rab-1A OS=Homo sapiens OX=9606 GN=RAB1A PE=1 SV=3 4.53 3960.6 - 2.57E+06 - - - -1.1851 - 3.042 0.502 - 248.7 1 2 0 -0.0022 17 0 0 0 0.00E+00 0.00E+00 - - - 6.9467 0.9999 221125_WJC_METTL3_EV_vs_WT_F02.24852.24852.2 2.25E-05 26-Nov K.IDFDSVSSIMASSQ.- "sp|Q9UBQ5|EIF3K_HUMAN,tr|A0A087WVB9|A0A087WVB9_HUMAN,tr|K7EK53|K7EK53_HUMAN,tr|K7ERF1|K7ERF1_HUMAN" 4 1485.6657 - 23463 24852 2 1485.664306 743.8401 Eukaryotic translation initiation factor 3 subunit K OS=Homo sapiens OX=9606 GN=EIF3K PE=1 SV=1 3.56 3960.7 - 2.48E+06 - - - -0.9551 - 2.338 0.549 - 250.5 1 2 0 -0.0014 14 0 0 0 - - - - - 5.2267 0.9999 221125_WJC_METTL3_EV_vs_WT_F02.24853.24853.3 0.000113 13/68 K.SNLAYDIVQLPTGLTGIK.V "sp|P34932|HSP74_HUMAN,tr|A0A087WTS8|A0A087WTS8_HUMAN,tr|A0A087WYC1|A0A087WYC1_HUMAN" 3 1902.0462 -1 23464 24853 3 1902.045579 635.0227 Heat shock 70 kDa protein 4 OS=Homo sapiens OX=9606 GN=HSPA4 PE=1 SV=4 5.55 3960.7 - 2.22E+06 - - - -0.3417 - 2.242 0.425 - 160.9 1 2 0 -0.0006 18 0 0 0 0.00E+00 0.00E+00 - - - 5.2886 1 221125_WJC_METTL3_EV_vs_WT_F02.24855.24855.2 2.62E-09 14/32 K.NATNVEQSFMTMAAEIK.K "sp|P62820|RAB1A_HUMAN,tr|E7END7|E7END7_HUMAN" 2 1883.8757 2.1 23466 24855 2 1883.87325 942.9451 Ras-related protein Rab-1A OS=Homo sapiens OX=9606 GN=RAB1A PE=1 SV=3 4.53 3960.9 - 2.02E+06 - - - -1.3191 - 2.91 0.669 - 342 1 2 0 -0.0025 17 0 0 0 1.08E+07 5.16E+06 - - - 6.6076 1 221125_WJC_METTL3_EV_vs_WT_F02.24863.24863.3 2.48E-12 28/84 R.K[136.11]PLVIIAEDVDGEALSTLVLNR[166.11].L "sp|P10809|CH60_HUMAN,tr|A0A7I2V2X6|A0A7I2V2X6_HUMAN,tr|A0A7I2YQK6|A0A7I2YQK6_HUMAN,tr|A0A7I2V599|A0A7I2V599_HUMAN,tr|A0A7I2YQ71|A0A7I2YQ71_HUMAN,tr|A0A7I2V5M1|A0A7I2V5M1_HUMAN,tr|A0A7I2V5K3|A0A7I2V5K3_HUMAN" 7 2382.3489 1.09 23473 24863 3 2382.346662 795.1236 "60 kDa heat shock protein, mitochondrial OS=Homo sapiens OX=9606 GN=HSPD1 PE=1 SV=2" 4.32 3961.5 - 1.53E+07 - - - -0.9381 - 5.18 0.656 - 1035.2 1 2 0 -0.0022 22 0 0 0 3.70E+08 3.40E+08 - - - 9.7527 1 221125_WJC_METTL3_EV_vs_WT_F02.24864.24864.3 1.22E-09 16/68 K.SNTPPMYLQADIEAFDIR[166.11].E sp|Q9HCE5|MET14_HUMAN 1 2090.0018 0.03 23474 24864 3 2089.999938 697.6745 N6-adenosine-methyltransferase non-catalytic subunit OS=Homo sapiens OX=9606 GN=METTL14 PE=1 SV=2 4.03 3961.6 - 6.79E+06 - - - -0.8966 - 2.91 0.617 - 280.3 1 2 0 -0.0019 18 0 0 0 8.01E+05 2.63E+07 - - - 8.0782 1 221125_WJC_METTL3_EV_vs_WT_F02.24865.24865.2 1.89E-08 17/26 K.GVDEVTIVNILTNR.S "sp|P07355|ANXA2_HUMAN,tr|H0YMU9|H0YMU9_HUMAN,tr|H0YMD9|H0YMD9_HUMAN,tr|H0YKX9|H0YKX9_HUMAN,tr|H0YMM1|H0YMM1_HUMAN,tr|H0YLV6|H0YLV6_HUMAN,tr|H0YMD0|H0YMD0_HUMAN,tr|H0YKV8|H0YKV8_HUMAN,tr|H0YMW4|H0YMW4_HUMAN,tr|H0YN42|H0YN42_HUMAN,tr|A0A7I2V4P4|A0A7I2V4P4_HUMAN,tr|H0YMT9|H0YMT9_HUMAN,tr|H0YKZ7|H0YKZ7_HUMAN,tr|H0YKL9|H0YKL9_HUMAN,tr|H0YNB8|H0YNB8_HUMAN,tr|H0YKS4|H0YKS4_HUMAN" 16 1541.8413 5.62 23475 24865 2 1541.840904 771.9279 Annexin A2 OS=Homo sapiens OX=9606 GN=ANXA2 PE=1 SV=2 4.37 3961.6 - 6.34E+06 - - - -0.2711 - 3.308 0.686 - 803.5 1 2 0 -0.0004 14 0 0 0 2.53E+07 4.49E+06 - - - 7.1098 1 221125_WJC_METTL3_EV_vs_WT_F02.24870.24870.2 2.50E-11 18/38 R.KLPIDVTEGEVISLGLPFGK.V "sp|P26599|PTBP1_HUMAN,tr|A0A6Q8PEX4|A0A6Q8PEX4_HUMAN,tr|A0A0U1RRM4|A0A0U1RRM4_HUMAN,tr|A6NLN1|A6NLN1_HUMAN,tr|K7EKJ7|K7EKJ7_HUMAN,tr|K7ELW5|K7ELW5_HUMAN,tr|K7ES59|K7ES59_HUMAN,tr|A0A7I2V4H6|A0A7I2V4H6_HUMAN,tr|A0A7I2V621|A0A7I2V621_HUMAN" 9 2111.1878 -1 23480 24870 2 2111.192254 1056.6012 Polypyrimidine tract-binding protein 1 OS=Homo sapiens OX=9606 GN=PTBP1 PE=1 SV=1 4.68 3961.9 - 2.81E+06 - - - 2.1059 - 3.652 0.736 - 503.2 1 2 0 0.0044 20 0 0 0 0.00E+00 0.00E+00 - - - 7.6602 1 221125_WJC_METTL3_EV_vs_WT_F02.24872.24872.3 2.78E-09 16/84 R.GFGFVTFSSMAEVDAAMAARPH.S "sp|P22626|ROA2_HUMAN,tr|A0A7I2YQN4|A0A7I2YQN4_HUMAN,tr|A0A7I2V4N0|A0A7I2V4N0_HUMAN,tr|A0A024RA28|A0A024RA28_HUMAN,tr|A0A7I2V4N1|A0A7I2V4N1_HUMAN,tr|A0A7I2V4I6|A0A7I2V4I6_HUMAN,tr|A0A087WUI2|A0A087WUI2_HUMAN,tr|A0A7I2V4S4|A0A7I2V4S4_HUMAN,tr|A0A7I2V323|A0A7I2V323_HUMAN,tr|A0A7I2V3P1|A0A7I2V3P1_HUMAN,tr|A0A7I2V3P7|A0A7I2V3P7_HUMAN" 11 2298.0562 -1 23482 24872 3 2298.057442 767.026 Heterogeneous nuclear ribonucleoproteins A2\B1 OS=Homo sapiens OX=9606 GN=HNRNPA2B1 PE=1 SV=2 5.32 3962 - 2.53E+06 - - - 0.5583 - 3.458 0.682 - 373.3 1 1 0 0.0013 22 0 0 0 0.00E+00 0.00E+00 - - - 9.0847 0.9999 221125_WJC_METTL3_EV_vs_WT_F02.24874.24874.3 1.68E-06 17/72 K.SLNNPAMLQVLLQPQLC[160.03]GR.A "sp|Q9HCJ3|RAVR2_HUMAN,tr|E9PE10|E9PE10_HUMAN" 2 2151.1293 2.74 23484 24874 3 2151.122405 718.0504 Ribonucleoprotein PTB-binding 2 OS=Homo sapiens OX=9606 GN=RAVER2 PE=1 SV=2 7.96 3962.2 - 1.69E+06 - - - -3.1886 - 3.011 0.457 - 223.3 1 2 0 -0.0069 19 0 0 0 8.20E+06 3.00E+06 - - - 6.3413 0.9997 221125_WJC_METTL3_EV_vs_WT_F02.24877.24877.2 1.85E-05 20-Dec R.SFWELIGEAAK.S sp|Q9HCY8|S10AE_HUMAN 1 1249.6343 -1 23487 24877 2 1249.635008 625.8244 Protein S100-A14 OS=Homo sapiens OX=9606 GN=S100A14 PE=1 SV=1 4.53 3962.5 - 1.40E+06 - - - 0.5754 - 1.718 0.453 - 276.7 1 2 0 0.0007 11 0 0 0 0.00E+00 0.00E+00 - - - 3.8506 0.9995 221125_WJC_METTL3_EV_vs_WT_F02.24881.24881.4 0.00461 14/114 R.KLPIDVTEGEVISLGLPFGK.V "sp|P26599|PTBP1_HUMAN,tr|A0A6Q8PEX4|A0A6Q8PEX4_HUMAN,tr|A0A0U1RRM4|A0A0U1RRM4_HUMAN,tr|A6NLN1|A6NLN1_HUMAN,tr|K7EKJ7|K7EKJ7_HUMAN,tr|K7ELW5|K7ELW5_HUMAN,tr|K7ES59|K7ES59_HUMAN,tr|A0A7I2V4H6|A0A7I2V4H6_HUMAN,tr|A0A7I2V621|A0A7I2V621_HUMAN" 9 2111.1878 -1 23490 24881 4 2111.186098 528.8042 Polypyrimidine tract-binding protein 1 OS=Homo sapiens OX=9606 GN=PTBP1 PE=1 SV=1 4.68 3962.9 - 536344 - - - -0.81 - 2.281 0.324 - 67.8 1 2 0 -0.0017 20 0 0 0 0.00E+00 0.00E+00 - - - 2.3213 0.9998 221125_WJC_METTL3_EV_vs_WT_F02.24882.24882.2 0.00135 18-Nov K.FAAQELIEVK[136.11].R "sp|Q86U44|MTA70_HUMAN,tr|F5H6D8|F5H6D8_HUMAN,tr|H0YFV6|H0YFV6_HUMAN,tr|B4DTN4|B4DTN4_HUMAN" 4 1154.6427 0.001 23491 24882 2 1154.642781 578.3286 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 4.53 3963 - 945466 - - - 0.0918 - 2.061 0.432 - 311.8 1 2 0 0.0001 10 0 0 0 0.00E+00 3.13E+07 - - - 4.2504 0.9779 221125_WJC_METTL3_EV_vs_WT_F02.24883.24883.3 0.00609 20/80 N.WITLGNQLDGIHLLDPDVVAR[166.11].F sp|Q86U44|MTA70_HUMAN 1 2354.2622 0.001 23492 24883 3 2354.251176 785.7613 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 4.41 3963.1 - 1.30E+07 - - - -4.6826 - 3.437 0.523 - 359.4 1 1 0 -0.011 21 0 0 0 0.00E+00 1.40E+07 - - - 7.3278 0.9999 221125_WJC_METTL3_EV_vs_WT_F02.24884.24884.3 4.33E-05 Dec-44 R.NLDLDSIIAEVK.A "sp|P48668|K2C6C_HUMAN,sp|P04259|K2C6B_HUMAN,sp|P13647|K2C5_HUMAN,sp|P35908|K22E_HUMAN,sp|O95678|K2C75_HUMAN,sp|Q5XKE5|K2C79_HUMAN,sp|P02538|K2C6A_HUMAN,tr|H0YI76|H0YI76_HUMAN,tr|H0YIN9|H0YIN9_HUMAN" 9 1328.7187 999 23493 24884 3 1328.717999 443.9135 "Keratin, type II cytoskeletal 6C OS=Homo sapiens OX=9606 GN=KRT6C PE=1 SV=3" 4.03 3963.1 - 6.84E+06 - - - -0.5629 - 2.483 0.345 - 271.3 1 2 0 -0.0007 12 0 0 0 5.63E+08 0.00E+00 - - - 4.9071 1 221125_WJC_METTL3_EV_vs_WT_F02.24885.24885.4 5.02E-13 24/126 R.K[136.11]PLVIIAEDVDGEALSTLVLNR[166.11].L "sp|P10809|CH60_HUMAN,tr|A0A7I2V2X6|A0A7I2V2X6_HUMAN,tr|A0A7I2YQK6|A0A7I2YQK6_HUMAN,tr|A0A7I2V599|A0A7I2V599_HUMAN,tr|A0A7I2YQ71|A0A7I2YQ71_HUMAN,tr|A0A7I2V5M1|A0A7I2V5M1_HUMAN,tr|A0A7I2V5K3|A0A7I2V5K3_HUMAN" 7 2382.3489 1.41 23494 24885 4 2382.348528 596.5945 "60 kDa heat shock protein, mitochondrial OS=Homo sapiens OX=9606 GN=HSPD1 PE=1 SV=2" 4.32 3963.2 - 6.31E+06 - - - -0.1549 - 4.22 0.678 - 474.3 1 2 0 -0.0004 22 0 0 0 4.30E+07 3.05E+07 - - - 5.5983 0.9999 221125_WJC_METTL3_EV_vs_WT_F02.24887.24887.2 9.17E-06 24-Dec K.EQSILELGSLLAK.T "sp|O00231|PSD11_HUMAN,tr|J3QRY4|J3QRY4_HUMAN" 2 1399.7922 -1 23496 24887 2 1399.792561 700.9034 26S proteasome non-ATPase regulatory subunit 11 OS=Homo sapiens OX=9606 GN=PSMD11 PE=1 SV=3 4.53 3963.3 - 4.78E+06 - - - 0.225 - 2.337 0.451 - 515.9 1 2 0 0.0003 13 0 0 0 0.00E+00 0.00E+00 - - - 4.5506 1 221125_WJC_METTL3_EV_vs_WT_F02.24888.24888.3 4.43E-11 24/76 K.AAELIANSLATAGDGLIELR[166.11].K "sp|P35232|PHB_HUMAN,tr|C9JZ20|C9JZ20_HUMAN,tr|C9JW96|C9JW96_HUMAN" 3 2007.0876 1.17 23497 24888 3 2007.086958 670.0365 Prohibitin OS=Homo sapiens OX=9606 GN=PHB PE=1 SV=1 4.14 3963.3 - 1.93E+06 - - - -0.3149 - 4.314 0.628 - 859.2 1 2 0 -0.0006 20 0 0 0 6.61E+07 5.63E+07 - - - 9.0879 0.9999 221125_WJC_METTL3_EV_vs_WT_F02.24889.24889.3 1.15E-07 Sep-68 R.LYIGLAGLATDVQTVAQR.L "sp|P49720|PSB3_HUMAN,tr|A0A087WXQ8|A0A087WXQ8_HUMAN,tr|A0A087WUL2|A0A087WUL2_HUMAN,tr|A0A087WY10|A0A087WY10_HUMAN" 4 1888.0418 -1 23498 24889 3 1888.043433 630.3545 Proteasome subunit beta type-3 OS=Homo sapiens OX=9606 GN=PSMB3 PE=1 SV=2 5.84 3963.4 - 1.93E+06 - - - 0.8586 - 2.514 0.42 - 102.6 1 2 0 0.0016 18 0 0 0 0.00E+00 0.00E+00 - - - 5.5177 0.9999 221125_WJC_METTL3_EV_vs_WT_F02.24890.24890.2 7.93E-08 24-Dec R.GNDTFVTLDEILR.L "sp|P49959|MRE11_HUMAN,tr|F5GXT0|F5GXT0_HUMAN,tr|F5H256|F5H256_HUMAN,tr|F8W7U8|F8W7U8_HUMAN,tr|F5H742|F5H742_HUMAN" 5 1491.7569 -1 23499 24890 2 1491.755783 746.8857 Double-strand break repair protein MRE11 OS=Homo sapiens OX=9606 GN=MRE11 PE=1 SV=3 4.03 3963.5 - 1.93E+06 - - - -0.7642 - 2.85 0.518 - 524.3 1 2 0 -0.0011 13 0 0 0 0.00E+00 0.00E+00 - - - 5.5546 1 221125_WJC_METTL3_EV_vs_WT_F02.24891.24891.2 1.11E-08 13/26 K.GVDEVTIVNILTNR[166.11].S "sp|P07355|ANXA2_HUMAN,tr|H0YMU9|H0YMU9_HUMAN,tr|H0YMD9|H0YMD9_HUMAN,tr|H0YKX9|H0YKX9_HUMAN,tr|H0YMM1|H0YMM1_HUMAN,tr|H0YLV6|H0YLV6_HUMAN,tr|H0YMD0|H0YMD0_HUMAN,tr|H0YKV8|H0YKV8_HUMAN,tr|H0YMW4|H0YMW4_HUMAN,tr|H0YN42|H0YN42_HUMAN,tr|A0A7I2V4P4|A0A7I2V4P4_HUMAN,tr|H0YMT9|H0YMT9_HUMAN,tr|H0YKZ7|H0YKZ7_HUMAN,tr|H0YKL9|H0YKL9_HUMAN,tr|H0YNB8|H0YNB8_HUMAN,tr|H0YKS4|H0YKS4_HUMAN" 16 1551.8496 -1 23500 24891 2 1551.851986 776.9321 Annexin A2 OS=Homo sapiens OX=9606 GN=ANXA2 PE=1 SV=2 4.37 3963.6 - 1.88E+06 - - - 1.5427 - 3.036 0.632 - 627.8 1 2 0 0.0024 14 0 0 0 0.00E+00 0.00E+00 - - - 6.495 1 221125_WJC_METTL3_EV_vs_WT_F02.24894.24894.2 9.33E-20 31/42 R.K[136.11]PLVIIAEDVDGEALSTLVLNR[166.11].L "sp|P10809|CH60_HUMAN,tr|A0A7I2V2X6|A0A7I2V2X6_HUMAN,tr|A0A7I2YQK6|A0A7I2YQK6_HUMAN,tr|A0A7I2V599|A0A7I2V599_HUMAN,tr|A0A7I2YQ71|A0A7I2YQ71_HUMAN,tr|A0A7I2V5M1|A0A7I2V5M1_HUMAN,tr|A0A7I2V5K3|A0A7I2V5K3_HUMAN" 7 2382.3489 1.22 23503 24894 2 2382.346083 1192.1817 "60 kDa heat shock protein, mitochondrial OS=Homo sapiens OX=9606 GN=HSPD1 PE=1 SV=2" 4.32 3964 - 1.11E+06 - - - -1.1812 - 5.432 0.804 - 3436 1 2 0 -0.0028 22 0 0 0 2.02E+07 1.66E+07 - - - 9.1391 0.9993 221125_WJC_METTL3_EV_vs_WT_F02.24895.24895.3 0.00026 Oct-52 K.GVDEVTIVNILTNR[166.11].S "sp|P07355|ANXA2_HUMAN,tr|H0YMU9|H0YMU9_HUMAN,tr|H0YMD9|H0YMD9_HUMAN,tr|H0YKX9|H0YKX9_HUMAN,tr|H0YMM1|H0YMM1_HUMAN,tr|H0YLV6|H0YLV6_HUMAN,tr|H0YMD0|H0YMD0_HUMAN,tr|H0YKV8|H0YKV8_HUMAN,tr|H0YMW4|H0YMW4_HUMAN,tr|H0YN42|H0YN42_HUMAN,tr|A0A7I2V4P4|A0A7I2V4P4_HUMAN,tr|H0YMT9|H0YMT9_HUMAN,tr|H0YKZ7|H0YKZ7_HUMAN,tr|H0YKL9|H0YKL9_HUMAN,tr|H0YNB8|H0YNB8_HUMAN,tr|H0YKS4|H0YKS4_HUMAN" 16 1551.8496 -1 23504 24895 3 1551.849645 518.2905 Annexin A2 OS=Homo sapiens OX=9606 GN=ANXA2 PE=1 SV=2 4.37 3964.1 - 1.08E+06 - - - 0.0342 - 1.909 0.296 - 136 1 2 0 0.0001 14 0 0 0 0.00E+00 0.00E+00 - - - 3.5584 0.9996 221125_WJC_METTL3_EV_vs_WT_F02.24897.24897.2 0.000223 14/22 R.SLDLDSIIAEVK.A sp|P04264|K2C1_HUMAN 1 1301.7078 999 23506 24897 2 1301.704434 651.8612 "Keratin, type II cytoskeletal 1 OS=Homo sapiens OX=9606 GN=KRT1 PE=1 SV=6" 4.03 3964.3 - 945249 - - - -2.6227 - 2.543 0.467 - 367.1 1 2 0 -0.0034 12 0 0 0 2.00E+10 0.00E+00 - - - 4.945 1 221125_WJC_METTL3_EV_vs_WT_F02.24904.24904.3 1.46E-12 27/84 R.KPLVIIAEDVDGEALSTLVLNR.L "sp|P10809|CH60_HUMAN,tr|A0A7I2V2X6|A0A7I2V2X6_HUMAN,tr|A0A7I2YQK6|A0A7I2YQK6_HUMAN,tr|A0A7I2V599|A0A7I2V599_HUMAN,tr|A0A7I2YQ71|A0A7I2YQ71_HUMAN,tr|A0A7I2V5M1|A0A7I2V5M1_HUMAN,tr|A0A7I2V5K3|A0A7I2V5K3_HUMAN" 7 2364.3264 1.1 23512 24904 3 2364.323591 789.1161 "60 kDa heat shock protein, mitochondrial OS=Homo sapiens OX=9606 GN=HSPD1 PE=1 SV=2" 4.32 3965.1 - 6.58E+07 - - - -1.1995 - 4.981 0.625 - 911.8 1 2 0 -0.0028 22 0 0 0 3.68E+08 3.36E+08 - - - 9.314 0.9998 221125_WJC_METTL3_EV_vs_WT_F02.24906.24906.3 0.000149 14/44 R.SLDLDSIIAEVK.A sp|P04264|K2C1_HUMAN 1 1301.7078 999 23514 24906 3 1301.705352 434.9099 "Keratin, type II cytoskeletal 1 OS=Homo sapiens OX=9606 GN=KRT1 PE=1 SV=6" 4.03 3965.2 - 1.44E+07 - - - -1.9175 - 2.543 0.37 - 315.3 1 2 0 -0.0025 12 0 0 0 9.57E+08 0.00E+00 - - - 5.2515 1 221125_WJC_METTL3_EV_vs_WT_F02.24907.24907.2 2.27E-08 18/38 K.AAELIANSLATAGDGLIELR.K "sp|P35232|PHB_HUMAN,tr|C9JZ20|C9JZ20_HUMAN,tr|C9JW96|C9JW96_HUMAN" 3 1997.0793 1.59 23515 24907 2 1997.074987 999.5469 Prohibitin OS=Homo sapiens OX=9606 GN=PHB PE=1 SV=1 4.14 3965.2 - 5.41E+06 - - - -2.1697 - 3.939 0.582 - 1010 1 2 0 -0.0043 20 0 0 0 3.68E+07 2.31E+07 - - - 6.7088 1 221125_WJC_METTL3_EV_vs_WT_F02.24908.24908.2 9.73E-06 24/38 K.AAELIANSLATAGDGLIELR[166.11].K "sp|P35232|PHB_HUMAN,tr|C9JZ20|C9JZ20_HUMAN,tr|C9JW96|C9JW96_HUMAN" 3 2007.0876 1.59 23516 24908 2 2007.082794 1004.5511 Prohibitin OS=Homo sapiens OX=9606 GN=PHB PE=1 SV=1 4.14 3965.3 - 4.68E+06 - - - -2.3895 - 4.914 0.643 - 2273.2 1 2 0 -0.0048 20 0 0 0 3.68E+07 2.31E+07 - - - 7.7029 1 221125_WJC_METTL3_EV_vs_WT_F02.24911.24911.2 2.18E-08 16/30 K.LAEDILNTMFDTSYSK[136.11].Q "sp|Q13045|FLII_HUMAN,tr|K7EQZ7|K7EQZ7_HUMAN,tr|J3QLR6|J3QLR6_HUMAN" 3 1854.8801 -1 23519 24911 2 1854.874897 928.4473 Protein flightless-1 homolog OS=Homo sapiens OX=9606 GN=FLII PE=1 SV=2 4.03 3965.6 - 1.21E+06 - - - -2.7948 - 3.435 0.617 - 1022.3 1 2 0 -0.0052 16 0 0 0 0.00E+00 0.00E+00 - - - 6.6304 1 221125_WJC_METTL3_EV_vs_WT_F02.24917.24917.3 1.39E-09 19/88 R.LLPALTVLDIHDNQLTSLPSAIR.E sp|Q9H9A6|LRC40_HUMAN 1 2499.4061 2.24 23523 24917 3 2499.405503 834.1426 Leucine-rich repeat-containing protein 40 OS=Homo sapiens OX=9606 GN=LRRC40 PE=1 SV=1 5.21 3966.1 - 4.44E+06 - - - -0.2285 - 4.049 0.572 - 281.4 1 2 0 -0.0006 23 0 0 0 2.89E+07 1.29E+07 - - - 8.1978 1 221125_WJC_METTL3_EV_vs_WT_F02.24918.24918.2 2.03E-09 28-Dec K.EFNEDGALAVLQQFK.D "sp|O60506|HNRPQ_HUMAN,tr|A0A7I2YQV8|A0A7I2YQV8_HUMAN,tr|A0A7I2YQN2|A0A7I2YQN2_HUMAN,tr|A0A7I2V5Q6|A0A7I2V5Q6_HUMAN,tr|A0A7I2V4Z0|A0A7I2V4Z0_HUMAN,tr|A0A7I2V4J0|A0A7I2V4J0_HUMAN,tr|F6UXX1|F6UXX1_HUMAN,tr|A0A7I2V346|A0A7I2V346_HUMAN" 8 1707.8468 1.23 23524 24918 2 1707.842107 854.9307 Heterogeneous nuclear ribonucleoprotein Q OS=Homo sapiens OX=9606 GN=SYNCRIP PE=1 SV=2 4.14 3966.2 - 3.47E+06 - - - -2.7485 - 2.746 0.589 - 470.5 1 2 0 -0.0047 15 0 0 0 2.62E+07 2.13E+07 - - - 5.8734 0.9834 221125_WJC_METTL3_EV_vs_WT_F02.24919.24919.2 0.000176 14/18 L.DLDSIIAEVK.A "sp|P48668|K2C6C_HUMAN,sp|P04264|K2C1_HUMAN,sp|P04259|K2C6B_HUMAN,sp|P13647|K2C5_HUMAN,sp|P35908|K22E_HUMAN,sp|O95678|K2C75_HUMAN,sp|Q5XKE5|K2C79_HUMAN,sp|P02538|K2C6A_HUMAN,tr|H0YI76|H0YI76_HUMAN,tr|H0YIN9|H0YIN9_HUMAN" 10 1101.5918 999 23525 24919 2 1101.589385 551.8032 "Keratin, type II cytoskeletal 6C OS=Homo sapiens OX=9606 GN=KRT6C PE=1 SV=3" 4.03 3966.3 - 2.28E+06 - - - -2.1514 - 2.305 0.48 - 435.9 1 1 0 -0.0024 10 0 0 0 2.12E+07 0.00E+00 - - - 4.9165 0.9384 221125_WJC_METTL3_EV_vs_WT_F02.24931.24931.2 0.000303 13/22 R.NLDLDSIIAEVK.A "sp|P48668|K2C6C_HUMAN,sp|P04259|K2C6B_HUMAN,sp|P13647|K2C5_HUMAN,sp|P35908|K22E_HUMAN,sp|O95678|K2C75_HUMAN,sp|Q5XKE5|K2C79_HUMAN,sp|P02538|K2C6A_HUMAN,tr|H0YI76|H0YI76_HUMAN,tr|H0YIN9|H0YIN9_HUMAN" 9 1328.7187 999 23533 24931 2 1330.725447 665.3666 "Keratin, type II cytoskeletal 6C OS=Homo sapiens OX=9606 GN=KRT6C PE=1 SV=3" 4.03 3967.7 - 4.25E+08 - - - 1510.2519 - 2.727 0.438 - 383.6 1 2 0 2.0067 12 0 0 0 1.15E+10 0.00E+00 - - - 4.2856 0.997 221125_WJC_METTL3_EV_vs_WT_F02.24933.24933.3 2.99E-11 25/80 N.WITLGNQLDGIHLLDPDVVAR.F sp|Q86U44|MTA70_HUMAN 1 2344.2539 0.04 23535 24933 3 2344.247726 782.4253 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 4.41 3967.8 - 1.74E+07 - - - -2.6465 - 3.465 0.61 - 584.8 1 1 0 -0.0062 21 0 0 0 9.33E+08 2.45E+10 - - - 8.3185 1 221125_WJC_METTL3_EV_vs_WT_F02.24934.24934.3 1.72E-09 21/56 R.TVFR[166.11]PPLDIYDVLIR[166.11].L "sp|Q9H6R4|NOL6_HUMAN,tr|A0A0C4DFX0|A0A0C4DFX0_HUMAN" 2 1836.0412 0.88 23536 24934 3 1836.03626 613.021 Nucleolar protein 6 OS=Homo sapiens OX=9606 GN=NOL6 PE=1 SV=2 5.63 3967.9 - 3.42E+06 - - - -2.7156 - 3.001 0.589 - 456.9 1 2 0 -0.005 15 0 0 0 1.64E+07 1.87E+07 - - - 7.9729 1 221125_WJC_METTL3_EV_vs_WT_F02.24935.24935.2 8.11E-07 20-Dec R.DLDDFQSWLSR[166.11].T "sp|Q01082|SPTB2_HUMAN,tr|A0A087WUZ3|A0A087WUZ3_HUMAN" 2 1390.6393 10.61 23537 24935 2 1390.632067 696.3269 "Spectrin beta chain, non-erythrocytic 1 OS=Homo sapiens OX=9606 GN=SPTBN1 PE=1 SV=2" 3.93 3968 - 3.32E+06 - - - -5.1753 - 2.552 0.589 - 507.6 1 2 0 -0.0072 11 0 0 0 1.41E+08 1.33E+07 - - - 5.9236 1 221125_WJC_METTL3_EV_vs_WT_F02.24942.24942.3 2.35E-10 27/88 R.IAIPGLAGAGNSVLLVSNLNPER.V "sp|P26599|PTBP1_HUMAN,tr|A0A0U1RRM4|A0A0U1RRM4_HUMAN,tr|A6NLN1|A6NLN1_HUMAN,tr|A0A7I2V621|A0A7I2V621_HUMAN,tr|K7EK45|K7EK45_HUMAN" 5 2274.2696 1.21 23541 24942 3 2274.265374 759.0971 Polypyrimidine tract-binding protein 1 OS=Homo sapiens OX=9606 GN=PTBP1 PE=1 SV=1 6 3968.9 - 1.15E+07 - - - -1.8498 - 3.798 0.533 - 395.7 1 2 0 -0.0042 23 0 0 0 6.39E+08 5.28E+08 - - - 7.6119 1 221125_WJC_METTL3_EV_vs_WT_F02.24943.24943.3 7.93E-08 23/88 R.IAIPGLAGAGNSVLLVSNLNPER[166.11].V "sp|P26599|PTBP1_HUMAN,tr|A0A0U1RRM4|A0A0U1RRM4_HUMAN,tr|A6NLN1|A6NLN1_HUMAN,tr|A0A7I2V621|A0A7I2V621_HUMAN,tr|K7EK45|K7EK45_HUMAN" 5 2284.2779 1.21 23542 24943 3 2284.277372 762.4332 Polypyrimidine tract-binding protein 1 OS=Homo sapiens OX=9606 GN=PTBP1 PE=1 SV=1 6 3968.9 - 9.04E+06 - - - -0.2097 - 3.863 0.606 - 550.5 1 2 0 -0.0005 23 0 0 0 6.39E+08 5.28E+08 - - - 8.4666 0.9999 221125_WJC_METTL3_EV_vs_WT_F02.24947.24947.3 1.85E-10 25/64 R.ELAILLGMLDPAEK[136.11]DEK[136.11].G sp|P30041|PRDX6_HUMAN 1 1900.0198 1.06 23544 24947 3 1900.015845 634.3472 Peroxiredoxin-6 OS=Homo sapiens OX=9606 GN=PRDX6 PE=1 SV=3 4.18 3969.5 - 1.87E+06 - - - -2.09 - 3.973 0.555 - 858.5 1 2 1 -0.004 17 0 0 0 2.53E+07 2.38E+07 - - - 8.2117 1 221125_WJC_METTL3_EV_vs_WT_F02.24950.24950.2 7.28E-17 26/36 L.TLGNQLDGIHLLDPDVVAR[166.11].F sp|Q86U44|MTA70_HUMAN 1 2055.0988 -1 23546 24950 2 2055.090626 1028.5567 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 4.41 3969.8 - 1.57E+06 - - - -3.9886 - 4.613 0.718 - 1063.3 1 1 0 -0.0082 19 0 0 0 0.00E+00 0.00E+00 - - - 8.1004 0.9998 221125_WJC_METTL3_EV_vs_WT_F02.24955.24955.3 5.24E-11 27/104 R.IPTAGIYGASYVPFAAPATATIATLQK.N "sp|A0AV96|RBM47_HUMAN,tr|B7Z8Z7|B7Z8Z7_HUMAN" 2 2692.4476 5.08 23549 24955 3 2692.433554 898.4898 RNA-binding protein 47 OS=Homo sapiens OX=9606 GN=RBM47 PE=1 SV=2 8.5 3970.4 - 3.19E+06 - - - -5.2187 - 3.693 0.621 - 454.3 1 2 0 -0.014 27 0 0 0 2.65E+07 5.22E+06 - - - 8.4653 1 221125_WJC_METTL3_EV_vs_WT_F02.24957.24957.3 7.84E-11 20/72 K.YMHSGPVVAMVWEGLNVVK.T "sp|P15531|NDKA_HUMAN,tr|Q32Q12|Q32Q12_HUMAN,tr|J3KPD9|J3KPD9_HUMAN,tr|E7ERL0|E7ERL0_HUMAN" 4 2115.0645 1.5 23550 24957 3 2116.060633 706.0288 Nucleoside diphosphate kinase A OS=Homo sapiens OX=9606 GN=NME1 PE=1 SV=1 6.75 3970.7 - 1.37E+06 - - - 470.9525 - 4.077 0.637 - 605.9 1 2 0 0.9961 19 0 0 0 5.56E+07 3.70E+07 - - - 8.8187 1 221125_WJC_METTL3_EV_vs_WT_F02.24960.24960.2 2.40E-09 23/40 N.WITLGNQLDGIHLLDPDVVAR.F sp|Q86U44|MTA70_HUMAN 1 2344.2539 0.01 23552 24960 2 2345.242933 1173.1342 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 4.41 3970.9 - 4.15E+06 - - - 421.8839 - 3.878 0.613 - 684.6 1 1 0 0.989 21 0 0 0 1.93E+07 1.43E+09 - - - 6.5902 1 221125_WJC_METTL3_EV_vs_WT_F02.24963.24963.2 8.27E-11 20/44 R.IAIPGLAGAGNSVLLVSNLNPER[166.11].V "sp|P26599|PTBP1_HUMAN,tr|A0A0U1RRM4|A0A0U1RRM4_HUMAN,tr|A6NLN1|A6NLN1_HUMAN,tr|A0A7I2V621|A0A7I2V621_HUMAN,tr|K7EK45|K7EK45_HUMAN" 5 2284.2779 1.91 23553 24963 2 2284.261249 1143.1462 Polypyrimidine tract-binding protein 1 OS=Homo sapiens OX=9606 GN=PTBP1 PE=1 SV=1 6 3971.3 - 4.52E+06 - - - -7.2679 - 3.661 0.607 - 912.5 1 2 0 -0.0166 23 0 0 0 9.65E+07 5.04E+07 - - - 6.7096 1 221125_WJC_METTL3_EV_vs_WT_F02.24967.24967.2 4.41E-16 28/44 R.IAIPGLAGAGNSVLLVSNLNPER.V "sp|P26599|PTBP1_HUMAN,tr|A0A0U1RRM4|A0A0U1RRM4_HUMAN,tr|A6NLN1|A6NLN1_HUMAN,tr|A0A7I2V621|A0A7I2V621_HUMAN,tr|K7EK45|K7EK45_HUMAN" 5 2274.2696 1.91 23555 24967 2 2274.26657 1138.1421 Polypyrimidine tract-binding protein 1 OS=Homo sapiens OX=9606 GN=PTBP1 PE=1 SV=1 6 3971.8 - 5.32E+06 - - - -1.3239 - 4.765 0.642 - 2075 1 2 0 -0.003 23 0 0 0 9.65E+07 5.04E+07 - - - 7.6204 0.9839 221125_WJC_METTL3_EV_vs_WT_F02.24968.24968.2 0.0875 28-Jul K.VSANVDSRIEMDSNK[136.11].G "sp|Q1X8D7|LRC36_HUMAN,tr|J3QSG3|J3QSG3_HUMAN,tr|J3QRT0|J3QRT0_HUMAN,tr|H3BNV0|H3BNV0_HUMAN,tr|H3BSQ6|H3BSQ6_HUMAN" 5 1671.7977 - 23556 24968 2 1671.798539 836.9062 Leucine-rich repeat-containing protein 36 OS=Homo sapiens OX=9606 GN=LRRC36 PE=1 SV=2 4.56 3971.8 - 4.84E+06 - - - 0.4725 - 1.416 0.3 - 77.8 1 2 1 0.0008 15 0 0 0 - - - - - 2.1117 0.9995 221125_WJC_METTL3_EV_vs_WT_F02.24982.24982.3 3.72E-07 16/76 K.LYIGNLSENAAPSDLESIFK.D "sp|O00425|IF2B3_HUMAN,tr|F8WD15|F8WD15_HUMAN" 2 2180.1001 0.75 23566 24982 3 2180.093929 727.7073 Insulin-like growth factor 2 mRNA-binding protein 3 OS=Homo sapiens OX=9606 GN=IGF2BP3 PE=1 SV=2 4.14 3973.3 - 5.38E+06 - - - -2.8375 - 3.124 0.319 - 217.2 1 2 0 -0.0062 20 0 0 0 2.65E+07 3.51E+07 - - - 4.8583 1 221125_WJC_METTL3_EV_vs_WT_F02.24988.24988.3 2.29E-06 16/48 R.TPLEQEIFNLLHK.N "sp|Q5TAP6|UT14C_HUMAN,sp|Q9BVJ6|UT14A_HUMAN,tr|X6RJY0|X6RJY0_HUMAN" 3 1580.8562 1.93 23571 24988 3 1580.852739 527.9594 U3 small nucleolar RNA-associated protein 14 homolog C OS=Homo sapiens OX=9606 GN=UTP14C PE=1 SV=1 5.37 3973.7 - 2.07E+06 - - - -2.2165 - 3.07 0.511 - 361.6 1 2 0 -0.0035 13 0 0 0 3.91E+07 2.02E+07 - - - 7.2774 1 221125_WJC_METTL3_EV_vs_WT_F02.24989.24989.2 9.48E-07 18/28 K.AEVEVADELLENLAK.V "sp|Q7L5D6|GET4_HUMAN,tr|C9JPA8|C9JPA8_HUMAN,tr|C9JHN8|C9JHN8_HUMAN" 3 1641.8461 2.55 23572 24989 2 1641.839618 821.9303 Golgi to ER traffic protein 4 homolog OS=Homo sapiens OX=9606 GN=GET4 PE=1 SV=1 3.91 3973.8 - 1.93E+06 - - - -3.9675 - 3.442 0.524 - 1049.3 1 2 0 -0.0065 15 0 0 0 1.43E+07 5.61E+06 - - - 5.9481 1 221125_WJC_METTL3_EV_vs_WT_F02.24990.24990.3 4.67E-07 16/64 K.LPNFGFVVFDDSEPVQK.V "sp|Q13283|G3BP1_HUMAN,tr|A0A7I2YQF2|A0A7I2YQF2_HUMAN,tr|A0A7I2V5M7|A0A7I2V5M7_HUMAN,tr|A0A7I2V5H1|A0A7I2V5H1_HUMAN,tr|A0A7I2V565|A0A7I2V565_HUMAN,tr|A0A7I2YQN9|A0A7I2YQN9_HUMAN,tr|A0A7I2YQH0|A0A7I2YQH0_HUMAN,tr|A0A7I2V494|A0A7I2V494_HUMAN" 8 1936.9571 1.14 23573 24990 3 1936.953284 646.6596 Ras GTPase-activating protein-binding protein 1 OS=Homo sapiens OX=9606 GN=G3BP1 PE=1 SV=1 4.03 3973.9 - 1.91E+06 - - - -1.9598 - 2.805 0.508 - 284 1 2 0 -0.0038 17 0 0 0 7.86E+07 6.93E+07 - - - 6.8083 1 221125_WJC_METTL3_EV_vs_WT_F02.24991.24991.2 7.71E-09 19/30 K.NAGNC[160.03]LSPAVIVGLLK[136.11].E "sp|O43175|SERA_HUMAN,tr|A0A2C9F2M7|A0A2C9F2M7_HUMAN,tr|A0A286YF22|A0A286YF22_HUMAN" 3 1632.9113 1.4 23574 24991 2 1632.911522 817.4629 D-3-phosphoglycerate dehydrogenase OS=Homo sapiens OX=9606 GN=PHGDH PE=1 SV=4 8.22 3974 - 1.35E+06 - - - 0.1586 - 3.376 0.59 - 1225.5 1 2 0 0.0003 16 0 0 0 3.04E+07 2.17E+07 - - - 6.39 0.9997 221125_WJC_METTL3_EV_vs_WT_F02.24994.24994.3 0.00727 Oct-52 K.NDVMNLLESAGFSR.S sp|Q9UQE7|SMC3_HUMAN 1 1551.7351 0.86 23577 24994 3 1551.731203 518.2523 Structural maintenance of chromosomes protein 3 OS=Homo sapiens OX=9606 GN=SMC3 PE=1 SV=2 4.37 3974.3 - 936008 - - - -2.5384 - 2.152 0.413 - 182.4 1 2 0 -0.0039 14 0 0 0 6.83E+06 7.91E+06 - - - 5.1802 1 221125_WJC_METTL3_EV_vs_WT_F02.24998.24998.3 3.22E-11 25/68 K.TVLELQYVLDK[136.11]LGDDEVR[166.11].T "sp|Q14444|CAPR1_HUMAN,tr|G3V153|G3V153_HUMAN,tr|E9PLA9|E9PLA9_HUMAN" 3 2122.1277 0.95 23579 24998 3 2122.129532 708.3832 Caprin-1 OS=Homo sapiens OX=9606 GN=CAPRIN1 PE=1 SV=2 4.1 3974.8 - 2.92E+07 - - - 0.877 - 4.12 0.64 - 639.1 1 2 1 0.0019 18 0 0 0 7.89E+07 8.29E+07 - - - 9.2005 1 221125_WJC_METTL3_EV_vs_WT_F02.24999.24999.2 4.80E-11 16/28 R.TEGLSVLSQAMAVIK.E "sp|P05198|IF2A_HUMAN,tr|H0YJS4|H0YJS4_HUMAN,tr|G3V4T5|G3V4T5_HUMAN" 3 1545.8436 1 23580 24999 2 1545.84286 773.9291 Eukaryotic translation initiation factor 2 subunit 1 OS=Homo sapiens OX=9606 GN=EIF2S1 PE=1 SV=3 5.66 3974.9 - 1.15E+07 - - - -0.4981 - 3.235 0.661 - 777.3 1 2 0 -0.0008 15 0 0 0 4.00E+07 4.02E+07 - - - 6.8093 1 221125_WJC_METTL3_EV_vs_WT_F02.25000.25000.3 2.34E-07 22/64 K.KEDLVFIFWAPESAPLK.S "sp|P23528|COF1_HUMAN,sp|Q9Y281|COF2_HUMAN,tr|E9PP50|E9PP50_HUMAN,tr|G3V1A4|G3V1A4_HUMAN,tr|E9PQB7|E9PQB7_HUMAN,tr|E9PK25|E9PK25_HUMAN" 6 1989.0612 1.38 23581 25000 3 1989.061876 664.0277 Cofilin-1 OS=Homo sapiens OX=9606 GN=CFL1 PE=1 SV=3 4.68 3974.9 - 8.61E+06 - - - 0.3645 - 3.374 0.62 - 646.4 1 2 0 0.0007 17 0 0 0 6.98E+07 5.06E+07 - - - 8.5244 1 221125_WJC_METTL3_EV_vs_WT_F02.25001.25001.3 1.16E-06 17/64 K.LPNFGFVVFDDSEPVQK[136.11].V "sp|Q13283|G3BP1_HUMAN,tr|A0A7I2YQF2|A0A7I2YQF2_HUMAN,tr|A0A7I2V5M7|A0A7I2V5M7_HUMAN,tr|A0A7I2V5H1|A0A7I2V5H1_HUMAN,tr|A0A7I2V565|A0A7I2V565_HUMAN,tr|A0A7I2YQN9|A0A7I2YQN9_HUMAN,tr|A0A7I2YQH0|A0A7I2YQH0_HUMAN,tr|A0A7I2V494|A0A7I2V494_HUMAN" 8 1944.9713 1.14 23582 25001 3 1944.970614 649.331 Ras GTPase-activating protein-binding protein 1 OS=Homo sapiens OX=9606 GN=G3BP1 PE=1 SV=1 4.03 3974.9 - 8.54E+06 - - - -0.3424 - 3.044 0.573 - 357.7 1 2 0 -0.0007 17 0 0 0 7.86E+07 6.93E+07 - - - 7.7404 1 221125_WJC_METTL3_EV_vs_WT_F02.25002.25002.2 5.34E-09 14/28 N.AAPGVDLTQLLNNMR.S "sp|P13645|K1C10_HUMAN,tr|A0A1B0GVI3|A0A1B0GVI3_HUMAN" 2 1611.8403 999 23583 25002 2 1611.839172 806.9274 "Keratin, type I cytoskeletal 10 OS=Homo sapiens OX=9606 GN=KRT10 PE=1 SV=6" 5.88 3975 - 7.66E+06 - - - -0.6849 - 2.504 0.614 - 685.8 1 1 0 -0.0011 15 0 0 0 3.64E+07 0.00E+00 - - - 5.8323 1 221125_WJC_METTL3_EV_vs_WT_F02.25003.25003.3 6.14E-08 14/48 R.TPLEQEIFNLLHK[136.11].N "sp|Q5TAP6|UT14C_HUMAN,sp|Q9BVJ6|UT14A_HUMAN,tr|X6RJY0|X6RJY0_HUMAN" 3 1588.8704 1.93 23584 25003 3 1588.869605 530.6308 U3 small nucleolar RNA-associated protein 14 homolog C OS=Homo sapiens OX=9606 GN=UTP14C PE=1 SV=1 5.37 3975 - 7.39E+06 - - - -0.5274 - 2.771 0.551 - 292.2 1 2 0 -0.0008 13 0 0 0 3.91E+07 2.02E+07 - - - 7.4462 1 221125_WJC_METTL3_EV_vs_WT_F02.25004.25004.3 5.08E-10 24/64 K.K[136.11]EDLVFIFWAPESAPLK[136.11].S "sp|P23528|COF1_HUMAN,sp|Q9Y281|COF2_HUMAN,tr|E9PP50|E9PP50_HUMAN,tr|G3V1A4|G3V1A4_HUMAN,tr|E9PQB7|E9PQB7_HUMAN,tr|E9PK25|E9PK25_HUMAN" 6 2005.0896 1.38 23585 25004 3 2005.088945 669.3705 Cofilin-1 OS=Homo sapiens OX=9606 GN=CFL1 PE=1 SV=3 4.68 3975.1 - 6.88E+06 - - - -0.3022 - 4.1 0.644 - 749.4 1 2 0 -0.0006 17 0 0 0 6.98E+07 5.06E+07 - - - 9.2844 1 221125_WJC_METTL3_EV_vs_WT_F02.25005.25005.2 9.57E-13 22/32 K.LPNFGFVVFDDSEPVQK[136.11].V "sp|Q13283|G3BP1_HUMAN,tr|A0A7I2YQF2|A0A7I2YQF2_HUMAN,tr|A0A7I2V5M7|A0A7I2V5M7_HUMAN,tr|A0A7I2V5H1|A0A7I2V5H1_HUMAN,tr|A0A7I2V565|A0A7I2V565_HUMAN,tr|A0A7I2YQN9|A0A7I2YQN9_HUMAN,tr|A0A7I2YQH0|A0A7I2YQH0_HUMAN,tr|A0A7I2V494|A0A7I2V494_HUMAN" 8 1944.9713 1.24 23586 25005 2 1944.969374 973.4929 Ras GTPase-activating protein-binding protein 1 OS=Homo sapiens OX=9606 GN=G3BP1 PE=1 SV=1 4.03 3975.1 - 6.88E+06 - - - -0.98 - 4.115 0.695 - 1067.2 1 2 0 -0.0019 17 0 0 0 1.03E+08 8.34E+07 - - - 7.6516 0.9997 221125_WJC_METTL3_EV_vs_WT_F02.25006.25006.3 8.02E-06 18/44 R.DTGIFLDLMHLK.K "sp|P12956|XRCC6_HUMAN,tr|B1AHC9|B1AHC9_HUMAN" 2 1401.7326 1.14 23587 25006 3 1401.732034 468.2515 X-ray repair cross-complementing protein 6 OS=Homo sapiens OX=9606 GN=XRCC6 PE=1 SV=2 5.21 3975.2 - 4.76E+06 - - - -0.4202 - 2.471 0.275 - 379.4 1 2 0 -0.0006 12 0 0 0 2.46E+07 2.16E+07 - - - 4.1133 0.9999 221125_WJC_METTL3_EV_vs_WT_F02.25008.25008.3 0.000178 13/44 R.DTGIFLDLMHLK[136.11].K "sp|P12956|XRCC6_HUMAN,tr|B1AHC9|B1AHC9_HUMAN" 2 1409.7468 -1 23589 25008 3 1409.746147 470.9229 X-ray repair cross-complementing protein 6 OS=Homo sapiens OX=9606 GN=XRCC6 PE=1 SV=2 5.21 3975.3 - 4.56E+06 - - - -0.4795 - 2.143 0.461 - 169 1 2 0 -0.0007 12 0 0 0 0.00E+00 0.00E+00 - - - 5.7922 1 221125_WJC_METTL3_EV_vs_WT_F02.25009.25009.2 2.10E-07 17/30 K.NAGNC[160.03]LSPAVIVGLLK.E "sp|O43175|SERA_HUMAN,tr|A0A2C9F2M7|A0A2C9F2M7_HUMAN,tr|A0A286YF22|A0A286YF22_HUMAN" 3 1624.8971 1.4 23590 25009 2 1624.897325 813.4558 D-3-phosphoglycerate dehydrogenase OS=Homo sapiens OX=9606 GN=PHGDH PE=1 SV=4 8.22 3975.4 - 4.09E+06 - - - 0.1612 - 3.229 0.64 - 934.3 1 2 0 0.0003 16 0 0 0 3.04E+07 2.17E+07 - - - 6.6498 0.9963 221125_WJC_METTL3_EV_vs_WT_F02.25010.25010.3 1.42E-06 13/56 N.AAPGVDLTQLLNNMR.S "sp|P13645|K1C10_HUMAN,tr|A0A1B0GVI3|A0A1B0GVI3_HUMAN" 2 1611.8403 999 23591 25010 3 1611.840745 538.2874 "Keratin, type I cytoskeletal 10 OS=Homo sapiens OX=9606 GN=KRT10 PE=1 SV=6" 5.88 3975.5 - 3.77E+06 - - - 0.291 - 2.472 0.486 - 200.2 1 1 0 0.0005 15 0 0 0 1.32E+07 0.00E+00 - - - 6.3198 1 221125_WJC_METTL3_EV_vs_WT_F02.25014.25014.3 1.88E-07 17/56 R.TEGLSVLSQAMAVIK.E "sp|P05198|IF2A_HUMAN,tr|H0YJS4|H0YJS4_HUMAN,tr|G3V4T5|G3V4T5_HUMAN" 3 1545.8436 -1 23595 25014 3 1545.845026 516.2885 Eukaryotic translation initiation factor 2 subunit 1 OS=Homo sapiens OX=9606 GN=EIF2S1 PE=1 SV=3 5.66 3975.8 - 3.11E+06 - - - 0.9031 - 3.005 0.457 - 361.9 1 2 0 0.0014 15 0 0 0 0.00E+00 0.00E+00 - - - 6.5057 1 221125_WJC_METTL3_EV_vs_WT_F02.25015.25015.2 7.93E-08 21/36 G.VTIAQGGVLPNIQAVLLPK.K "sp|P16104|H2AX_HUMAN,sp|Q9BTM1|H2AJ_HUMAN,sp|Q93077|H2A1C_HUMAN,sp|Q99878|H2A1J_HUMAN,sp|Q16777|H2A2C_HUMAN,sp|Q8IUE6|H2A2B_HUMAN,sp|Q96QV6|H2A1A_HUMAN,sp|P04908|H2A1B_HUMAN,sp|P20671|H2A1D_HUMAN,sp|P0C0S8|H2A1_HUMAN,sp|Q6FI13|H2A2A_HUMAN,sp|Q96KK5|H2A1H_HUMAN,sp|Q7L7L0|H2A3_HUMAN,tr|A0A0U1RR32|A0A0U1RR32_HUMAN,tr|A0A0U1RRH7|A0A0U1RRH7_HUMAN,tr|H0YFX9|H0YFX9_HUMAN" 16 1930.1615 1.3 23596 25015 2 1930.162075 966.088 Histone H2AX OS=Homo sapiens OX=9606 GN=H2AX PE=1 SV=2 8.72 3975.9 - 2.99E+06 - - - 0.2803 - 3.617 0.548 - 1021.9 1 1 0 0.0005 19 0 0 0 8.78E+08 6.74E+08 - - - 6.2492 1 221125_WJC_METTL3_EV_vs_WT_F02.25021.25021.2 1.97E-08 18/32 R.TDITYPAGFMDVISIDK[136.11].T sp|P62701|RS4X_HUMAN 1 1892.9321 0.9 23601 25021 2 1892.924634 947.4733 "40S ribosomal protein S4, X isoform OS=Homo sapiens OX=9606 GN=RPS4X PE=1 SV=2" 3.93 3976.5 - 1.41E+07 - - - -3.9531 - 3.337 0.624 - 941.9 1 2 0 -0.0075 17 0 0 0 1.17E+08 1.31E+08 - - - 6.6102 1 221125_WJC_METTL3_EV_vs_WT_F02.25022.25022.2 1.49E-09 16/26 Q.GLIGSVEEQLAQLR.C "sp|Q04695|K1C17_HUMAN,sp|P08779|K1C16_HUMAN,tr|A0A3B3IS58|A0A3B3IS58_HUMAN,tr|F5GWP8|F5GWP8_HUMAN,tr|K7ENW6|K7ENW6_HUMAN" 5 1511.8308 999 23602 25022 2 1511.828503 756.9227 "Keratin, type I cytoskeletal 17 OS=Homo sapiens OX=9606 GN=KRT17 PE=1 SV=2" 4.53 3976.5 - 1.13E+07 - - - -1.4909 - 3.343 0.606 - 1112 1 1 0 -0.0023 14 0 0 0 7.64E+07 0.00E+00 - - - 6.5448 1 221125_WJC_METTL3_EV_vs_WT_F02.25024.25024.3 7.50E-09 14/68 R.LTSSVSC[160.03]ALDEAAAALTR.M "sp|O75179|ANR17_HUMAN,sp|Q8IWZ3|ANKH1_HUMAN,tr|E9PDP5|E9PDP5_HUMAN,tr|H0YM23|H0YM23_HUMAN,tr|A0A1W2PQ15|A0A1W2PQ15_HUMAN,tr|D6RHC4|D6RHC4_HUMAN" 6 1834.9095 -1 23604 25024 3 1834.908454 612.6438 Ankyrin repeat domain-containing protein 17 OS=Homo sapiens OX=9606 GN=ANKRD17 PE=1 SV=3 4.37 3976.6 - 8.88E+06 - - - -0.5581 - 3.25 0.655 - 270.1 1 2 0 -0.001 18 0 0 0 0.00E+00 0.00E+00 - - - 8.7773 0.9976 221125_WJC_METTL3_EV_vs_WT_F02.25025.25025.3 0.000428 19/52 Q.GLIGSVEEQLAQLR.C "sp|Q04695|K1C17_HUMAN,sp|P08779|K1C16_HUMAN,tr|A0A3B3IS58|A0A3B3IS58_HUMAN,tr|F5GWP8|F5GWP8_HUMAN,tr|K7ENW6|K7ENW6_HUMAN" 5 1511.8308 140.4 23605 25025 3 1511.828443 504.9509 "Keratin, type I cytoskeletal 17 OS=Homo sapiens OX=9606 GN=KRT17 PE=1 SV=2" 4.53 3976.7 - 8.41E+06 - - - -1.5306 - 2.849 0.535 - 568.2 1 1 0 -0.0023 14 0 0 0 4.78E+07 3.41E+05 - - - 7.2864 1 221125_WJC_METTL3_EV_vs_WT_F02.25026.25026.2 1.83E-11 15/32 K.MSATFIGNSTAIQELFK[136.11].R "sp|Q9BVA1|TBB2B_HUMAN,sp|Q13885|TBB2A_HUMAN,sp|P68371|TBB4B_HUMAN" 3 1864.9484 -1 23606 25026 2 1864.946733 933.4815 Tubulin beta-2B chain OS=Homo sapiens OX=9606 GN=TUBB2B PE=1 SV=1 5.75 3976.7 - 6.68E+06 - - - -0.9132 - 3.237 0.535 - 649.7 1 2 0 -0.0017 17 0 0 0 0.00E+00 0.00E+00 - - - 5.8799 1 221125_WJC_METTL3_EV_vs_WT_F02.25027.25027.3 2.66E-10 14/68 R.LTSSVSC[160.03]ALDEAAAALTR[166.11].M "sp|O75179|ANR17_HUMAN,sp|Q8IWZ3|ANKH1_HUMAN,tr|E9PDP5|E9PDP5_HUMAN,tr|H0YM23|H0YM23_HUMAN,tr|A0A1W2PQ15|A0A1W2PQ15_HUMAN,tr|D6RHC4|D6RHC4_HUMAN" 6 1844.9177 -1 23607 25027 3 1844.912817 615.9799 Ankyrin repeat domain-containing protein 17 OS=Homo sapiens OX=9606 GN=ANKRD17 PE=1 SV=3 4.37 3976.8 - 6.16E+06 - - - -2.6727 - 3.023 0.594 - 265 1 2 0 -0.0049 18 0 0 0 0.00E+00 0.00E+00 - - - 7.9158 1 221125_WJC_METTL3_EV_vs_WT_F02.25028.25028.2 1.73E-12 17/32 K.MSATFIGNSTAIQELFK.R "sp|Q9BVA1|TBB2B_HUMAN,sp|Q13885|TBB2A_HUMAN,sp|P68371|TBB4B_HUMAN" 3 1856.9342 -1 23608 25028 2 1856.932222 929.4744 Tubulin beta-2B chain OS=Homo sapiens OX=9606 GN=TUBB2B PE=1 SV=1 5.75 3976.8 - 5.72E+06 - - - -1.0846 - 3.407 0.627 - 852.3 1 2 0 -0.002 17 0 0 0 0.00E+00 0.00E+00 - - - 6.6852 1 221125_WJC_METTL3_EV_vs_WT_F02.25031.25031.3 9.97E-06 16/64 K.R[166.11]FPELESLVPNALDYIR[166.11].T "sp|Q8WWY3|PRP31_HUMAN,tr|E7EVX8|E7EVX8_HUMAN,tr|E7EU94|E7EU94_HUMAN,tr|E7ESX0|E7ESX0_HUMAN,tr|E7EN72|E7EN72_HUMAN" 5 2051.0955 2.95 23611 25031 3 2051.095033 684.7058 U4\U6 small nuclear ribonucleoprotein Prp31 OS=Homo sapiens OX=9606 GN=PRPF31 PE=1 SV=2 4.68 3977 - 4.46E+06 - - - -0.2111 - 3.054 0.559 - 234.3 1 2 0 -0.0004 17 0 0 0 4.26E+07 1.45E+07 - - - 7.5927 0.9997 221125_WJC_METTL3_EV_vs_WT_F02.25033.25033.3 0.00236 Sep-64 K.MSATFIGNSTAIQELFK[136.11].R "sp|Q9BVA1|TBB2B_HUMAN,sp|Q13885|TBB2A_HUMAN,sp|P68371|TBB4B_HUMAN" 3 1864.9484 -1 23613 25033 3 1864.947444 622.6568 Tubulin beta-2B chain OS=Homo sapiens OX=9606 GN=TUBB2B PE=1 SV=1 5.75 3977.1 - 3.73E+06 - - - -0.5319 - 2.069 0.344 - 127.6 1 2 0 -0.001 17 0 0 0 0.00E+00 0.00E+00 - - - 4.2118 1 221125_WJC_METTL3_EV_vs_WT_F02.25034.25034.2 1.52E-10 20/34 R.LTSSVSC[160.03]ALDEAAAALTR.M "sp|O75179|ANR17_HUMAN,sp|Q8IWZ3|ANKH1_HUMAN,tr|E9PDP5|E9PDP5_HUMAN,tr|H0YM23|H0YM23_HUMAN,tr|A0A1W2PQ15|A0A1W2PQ15_HUMAN,tr|D6RHC4|D6RHC4_HUMAN" 6 1834.9095 -1 23614 25034 2 1834.907958 918.462 Ankyrin repeat domain-containing protein 17 OS=Homo sapiens OX=9606 GN=ANKRD17 PE=1 SV=3 4.37 3977.1 - 3.56E+06 - - - -0.8284 - 3.942 0.663 - 1115.4 1 2 0 -0.0015 18 0 0 0 0.00E+00 0.00E+00 - - - 7.3098 1 221125_WJC_METTL3_EV_vs_WT_F02.25036.25036.3 6.96E-09 14/48 R.NDLEEAFIHFMGK[136.11].G "sp|Q9BRR6|ADPGK_HUMAN,tr|H3BRS6|H3BRS6_HUMAN" 2 1557.7377 -1 23616 25036 3 1557.733866 520.2532 ADP-dependent glucokinase OS=Homo sapiens OX=9606 GN=ADPGK PE=1 SV=1 4.65 3977.3 - 3.25E+06 - - - -2.4709 - 2.85 0.593 - 376 1 2 0 -0.0038 13 0 0 0 0.00E+00 0.00E+00 - - - 7.9899 1 221125_WJC_METTL3_EV_vs_WT_F02.25038.25038.3 2.11E-07 14/48 R.NDLEEAFIHFMGK.G "sp|Q9BRR6|ADPGK_HUMAN,tr|H3BRS6|H3BRS6_HUMAN" 2 1549.7235 1.53 23618 25038 3 1549.723625 517.5818 ADP-dependent glucokinase OS=Homo sapiens OX=9606 GN=ADPGK PE=1 SV=1 4.65 3977.4 - 2.96E+06 - - - 0.071 - 2.766 0.618 - 337.8 1 2 0 0.0001 13 0 0 0 9.67E+06 6.33E+06 - - - 8.1885 0.9985 221125_WJC_METTL3_EV_vs_WT_F02.25042.25042.3 7.30E-07 18/72 G.VTIAQGGVLPNIQAVLLPK[136.11].K "sp|P16104|H2AX_HUMAN,sp|Q9BTM1|H2AJ_HUMAN,sp|Q93077|H2A1C_HUMAN,sp|Q99878|H2A1J_HUMAN,sp|Q16777|H2A2C_HUMAN,sp|Q8IUE6|H2A2B_HUMAN,sp|Q96QV6|H2A1A_HUMAN,sp|P04908|H2A1B_HUMAN,sp|P20671|H2A1D_HUMAN,sp|P0C0S8|H2A1_HUMAN,sp|Q6FI13|H2A2A_HUMAN,sp|Q96KK5|H2A1H_HUMAN,sp|Q7L7L0|H2A3_HUMAN,tr|A0A0U1RR32|A0A0U1RR32_HUMAN,tr|A0A0U1RRH7|A0A0U1RRH7_HUMAN,tr|H0YFX9|H0YFX9_HUMAN" 16 1938.1757 1.3 23621 25042 3 1938.172918 647.0659 Histone H2AX OS=Homo sapiens OX=9606 GN=H2AX PE=1 SV=2 8.72 3977.7 - 4.27E+07 - - - -1.4529 - 3.287 0.584 - 337.4 1 1 0 -0.0028 19 0 0 0 1.10E+09 8.47E+08 - - - 7.9738 1 221125_WJC_METTL3_EV_vs_WT_F02.25043.25043.2 6.93E-10 19/36 G.VTIAQGGVLPNIQAVLLPK[136.11].K "sp|P16104|H2AX_HUMAN,sp|Q9BTM1|H2AJ_HUMAN,sp|Q93077|H2A1C_HUMAN,sp|Q99878|H2A1J_HUMAN,sp|Q16777|H2A2C_HUMAN,sp|Q8IUE6|H2A2B_HUMAN,sp|Q96QV6|H2A1A_HUMAN,sp|P04908|H2A1B_HUMAN,sp|P20671|H2A1D_HUMAN,sp|P0C0S8|H2A1_HUMAN,sp|Q6FI13|H2A2A_HUMAN,sp|Q96KK5|H2A1H_HUMAN,sp|Q7L7L0|H2A3_HUMAN,tr|A0A0U1RR32|A0A0U1RR32_HUMAN,tr|A0A0U1RRH7|A0A0U1RRH7_HUMAN,tr|H0YFX9|H0YFX9_HUMAN" 16 1938.1757 1.3 23622 25043 2 1938.172282 970.0951 Histone H2AX OS=Homo sapiens OX=9606 GN=H2AX PE=1 SV=2 8.72 3977.7 - 2.38E+07 - - - -1.7811 - 3.384 0.589 - 916.6 1 1 0 -0.0035 19 0 0 0 8.78E+08 6.74E+08 - - - 6.3874 1 221125_WJC_METTL3_EV_vs_WT_F02.25044.25044.2 4.42E-08 15/32 R.TDITYPAGFMDVISIDK.T sp|P62701|RS4X_HUMAN 1 1884.9179 0.9 23623 25044 2 1884.916221 943.4662 "40S ribosomal protein S4, X isoform OS=Homo sapiens OX=9606 GN=RPS4X PE=1 SV=2" 3.93 3977.8 - 1.85E+07 - - - -0.8998 - 2.87 0.619 - 535.3 1 2 0 -0.0017 17 0 0 0 1.17E+08 1.31E+08 - - - 6.2045 1 221125_WJC_METTL3_EV_vs_WT_F02.25046.25046.3 1.36E-10 24/84 K.LLDFGSLSNLQVTQPTVGMNFK.T "sp|P08708|RS17_HUMAN,tr|H3BNC9|H3BNC9_HUMAN" 2 2408.241 1.13 23625 25046 3 2408.238167 803.7543 40S ribosomal protein S17 OS=Homo sapiens OX=9606 GN=RPS17 PE=1 SV=2 5.84 3977.9 - 7.93E+06 - - - -1.1693 - 4.058 0.637 - 430.1 1 2 0 -0.0028 22 0 0 0 2.26E+08 2.00E+08 - - - 8.9619 0.9999 221125_WJC_METTL3_EV_vs_WT_F02.25050.25050.2 0.000957 14/26 R.ISLPLPNFSSLNLR[166.11].E "sp|P08670|VIME_HUMAN,tr|B0YJC4|B0YJC4_HUMAN" 2 1579.8961 1.96 23629 25050 2 1579.89409 790.9554 Vimentin OS=Homo sapiens OX=9606 GN=VIM PE=1 SV=4 9.75 3978 - 5.20E+06 - - - -1.3026 - 2.496 0.527 - 529.8 1 2 0 -0.0021 14 0 0 0 1.36E+09 6.93E+08 - - - 5.2281 1 221125_WJC_METTL3_EV_vs_WT_F02.25052.25052.2 3.18E-09 16/30 R.TQGFLALFSGDTGEIK[136.11].S "sp|Q9Y230|RUVB2_HUMAN,tr|M0R0Y3|M0R0Y3_HUMAN" 2 1690.8658 0.51 23631 25052 2 1690.866921 846.4402 RuvB-like 2 OS=Homo sapiens OX=9606 GN=RUVBL2 PE=1 SV=3 4.37 3978.1 - 4.44E+06 - - - 0.6914 - 3.262 0.518 - 972.8 1 2 0 0.0012 16 0 0 0 8.77E+06 1.71E+07 - - - 5.7734 1 221125_WJC_METTL3_EV_vs_WT_F02.25053.25053.3 2.05E-06 14/64 R.TDITYPAGFMDVISIDK.T sp|P62701|RS4X_HUMAN 1 1884.9179 1.05 23632 25053 3 1884.915883 629.3132 "40S ribosomal protein S4, X isoform OS=Homo sapiens OX=9606 GN=RPS4X PE=1 SV=2" 3.93 3978.2 - 4.21E+06 - - - -1.0791 - 2.722 0.583 - 329.3 1 2 0 -0.002 17 0 0 0 2.03E+07 1.93E+07 - - - 7.5691 1 221125_WJC_METTL3_EV_vs_WT_F02.25054.25054.3 1.76E-09 14/64 R.TDITYPAGFMDVISIDK[136.11].T sp|P62701|RS4X_HUMAN 1 1892.9321 1.05 23633 25054 3 1892.930458 631.9846 "40S ribosomal protein S4, X isoform OS=Homo sapiens OX=9606 GN=RPS4X PE=1 SV=2" 3.93 3978.2 - 4.07E+06 - - - -0.8764 - 2.954 0.6 - 322.7 1 2 0 -0.0017 17 0 0 0 2.03E+07 1.93E+07 - - - 7.9653 1 221125_WJC_METTL3_EV_vs_WT_F02.25056.25056.2 0.00011 13/30 R.TQGFLALFSGDTGEIK.S "sp|Q9Y230|RUVB2_HUMAN,tr|M0R0Y3|M0R0Y3_HUMAN" 2 1682.8516 -1 23635 25056 2 1682.850355 842.4331 RuvB-like 2 OS=Homo sapiens OX=9606 GN=RUVBL2 PE=1 SV=3 4.37 3978.3 - 3.68E+06 - - - -0.7113 - 3.213 0.605 - 541 1 2 0 -0.0012 16 0 0 0 0.00E+00 0.00E+00 - - - 6.3788 1 221125_WJC_METTL3_EV_vs_WT_F02.25057.25057.2 7.09E-11 14/34 K.DGVFLYFEDNAGVIVNNK[136.11].G "sp|P62829|RL23_HUMAN,tr|J3KT29|J3KT29_HUMAN,tr|J3KTJ3|J3KTJ3_HUMAN" 3 2020.9986 2.24 23636 25057 2 2020.99755 1011.5066 60S ribosomal protein L23 OS=Homo sapiens OX=9606 GN=RPL23 PE=1 SV=1 4.03 3978.4 - 2.87E+06 - - - -0.4983 - 3.06 0.69 - 485.1 1 2 0 -0.001 18 0 0 0 2.19E+07 9.78E+06 - - - 6.8867 1 221125_WJC_METTL3_EV_vs_WT_F02.25058.25058.2 1.35E-10 17/26 K.YC[160.03]YLQNEVFGLFQK.L sp|P15924|DESP_HUMAN 1 1807.8603 -1 23637 25058 2 1807.857326 904.9374 Desmoplakin OS=Homo sapiens OX=9606 GN=DSP PE=1 SV=3 5.99 3978.5 - 1.99E+06 - - - -1.6688 - 3.013 0.725 - 880.2 1 2 0 -0.003 14 0 0 0 0.00E+00 0.00E+00 - - - 7.1627 0.9998 221125_WJC_METTL3_EV_vs_WT_F02.25059.25059.3 0.000389 Sep-56 K.SSFADISNLLQIEPR.N sp|Q15785|TOM34_HUMAN 1 1688.8734 -1 23638 25059 3 1688.870929 563.9651 Mitochondrial import receptor subunit TOM34 OS=Homo sapiens OX=9606 GN=TOMM34 PE=1 SV=2 4.37 3978.6 - 1.77E+06 - - - -1.4335 - 1.968 0.41 - 79 1 2 0 -0.0024 15 0 0 0 0.00E+00 0.00E+00 - - - 4.877 1 221125_WJC_METTL3_EV_vs_WT_F02.25062.25062.3 1.60E-05 13/72 R.MPAEIVVLLDSEDNPSLPK.R sp|Q9BUA3|SPNDC_HUMAN 1 2066.0606 -1 23640 25062 3 2066.058534 689.6941 Spindlin interactor and repressor of chromatin-binding protein OS=Homo sapiens OX=9606 GN=SPINDOC PE=1 SV=3 3.92 3978.9 - 998721 - - - -0.9801 - 2.646 0.471 - 138.8 1 2 0 -0.002 19 0 0 0 0.00E+00 0.00E+00 - - - 6.1812 1 221125_WJC_METTL3_EV_vs_WT_F02.25063.25063.3 0.000215 19/84 K.LLDFGSLSNLQVTQPTVGMNFK[136.11].T "sp|P08708|RS17_HUMAN,tr|H3BNC9|H3BNC9_HUMAN" 2 2416.2552 1.05 23641 25063 3 2416.25202 806.4257 40S ribosomal protein S17 OS=Homo sapiens OX=9606 GN=RPS17 PE=1 SV=2 5.84 3979 - 6.57E+07 - - - -1.3091 - 3.564 0.564 - 260.2 1 2 0 -0.0032 22 0 0 0 2.26E+08 2.15E+08 - - - 7.8402 1 221125_WJC_METTL3_EV_vs_WT_F02.25065.25065.2 5.71E-14 24/42 K.LLDFGSLSNLQVTQPTVGMNFK.T "sp|P08708|RS17_HUMAN,tr|H3BNC9|H3BNC9_HUMAN" 2 2408.241 1.2 23643 25065 2 2408.239046 1205.1278 40S ribosomal protein S17 OS=Homo sapiens OX=9606 GN=RPS17 PE=1 SV=2 5.84 3979.1 - 1.06E+07 - - - -0.8043 - 4.181 0.727 - 1129.8 1 2 0 -0.0019 22 0 0 0 4.52E+07 3.77E+07 - - - 7.9271 1 221125_WJC_METTL3_EV_vs_WT_F02.25066.25066.2 4.86E-09 16/26 R.TGEAIVDAALSALR.Q sp|Q15084|PDIA6_HUMAN 1 1385.7514 1.2 23644 25066 2 1385.750533 693.883 Protein disulfide-isomerase A6 OS=Homo sapiens OX=9606 GN=PDIA6 PE=1 SV=1 4.37 3979.1 - 8.28E+06 - - - -0.6574 - 3.431 0.541 - 888.9 1 2 0 -0.0009 14 0 0 0 3.96E+07 3.31E+07 - - - 6.1303 1 221125_WJC_METTL3_EV_vs_WT_F02.25067.25067.2 9.44E-11 19/34 K.TGLLSGLDIMEVNPSLGK.T "sp|P05089|ARGI1_HUMAN,tr|A0A5F9ZGN6|A0A5F9ZGN6_HUMAN,tr|A0A5F9ZH78|A0A5F9ZH78_HUMAN" 3 1842.9761 -1 23645 25067 2 1842.973417 922.4953 Arginase-1 OS=Homo sapiens OX=9606 GN=ARG1 PE=1 SV=2 4.37 3979.2 - 6.68E+06 - - - -1.4563 - 3.827 0.649 - 840.4 1 2 0 -0.0027 18 0 0 0 0.00E+00 0.00E+00 - - - 7.1332 1 221125_WJC_METTL3_EV_vs_WT_F02.25068.25068.2 9.84E-06 16/26 R.TGEAIVDAALSALR[166.11].Q sp|Q15084|PDIA6_HUMAN 1 1395.7597 1.2 23646 25068 2 1395.758604 698.8871 Protein disulfide-isomerase A6 OS=Homo sapiens OX=9606 GN=PDIA6 PE=1 SV=1 4.37 3979.2 - 6.13E+06 - - - -0.7953 - 3.366 0.594 - 932.8 1 2 0 -0.0011 14 0 0 0 3.96E+07 3.31E+07 - - - 6.4737 1 221125_WJC_METTL3_EV_vs_WT_F02.25069.25069.2 6.63E-07 16/26 K.AGVMALANLLQIQR.H "sp|Q9Y224|RTRAF_HUMAN,tr|G3V4C6|G3V4C6_HUMAN,tr|H0YJB9|H0YJB9_HUMAN" 3 1496.8497 -1 23647 25069 2 1496.848363 749.4321 "RNA transcription, translation and transport factor protein OS=Homo sapiens OX=9606 GN=RTRAF PE=1 SV=1" 9.79 3979.2 - 5.99E+06 - - - -0.9052 - 3.333 0.545 - 1014.5 1 2 0 -0.0014 14 0 0 0 0.00E+00 0.00E+00 - - - 6.087 0.9998 221125_WJC_METTL3_EV_vs_WT_F02.25070.25070.2 3.51E-07 15/26 K.AGVMALANLLQIQR[166.11].H "sp|Q9Y224|RTRAF_HUMAN,tr|G3V4C6|G3V4C6_HUMAN,tr|H0YJB9|H0YJB9_HUMAN" 3 1506.858 0.82 23648 25070 2 1506.861406 754.4363 "RNA transcription, translation and transport factor protein OS=Homo sapiens OX=9606 GN=RTRAF PE=1 SV=1" 9.79 3979.3 - 4.22E+06 - - - 2.2683 - 3.176 0.494 - 933.5 1 2 0 0.0034 14 0 0 0 1.37E+07 1.67E+07 - - - 5.5886 1 221125_WJC_METTL3_EV_vs_WT_F02.25071.25071.3 5.58E-08 18/52 R.TGEAIVDAALSALR.Q sp|Q15084|PDIA6_HUMAN 1 1385.7514 1.6 23649 25071 3 1385.749784 462.9244 Protein disulfide-isomerase A6 OS=Homo sapiens OX=9606 GN=PDIA6 PE=1 SV=1 4.37 3979.4 - 3.62E+06 - - - -1.1979 - 3.475 0.59 - 489.4 1 2 0 -0.0017 14 0 0 0 1.44E+07 9.04E+06 - - - 8.4277 0.9714 221125_WJC_METTL3_EV_vs_WT_F02.25072.25072.3 0.096 Oct-52 K.YC[160.03]YLQNEVFGLFQK.L sp|P15924|DESP_HUMAN 1 1807.8603 -1 23650 25072 3 1807.859133 603.6274 Desmoplakin OS=Homo sapiens OX=9606 GN=DSP PE=1 SV=3 5.99 3979.4 - 3.31E+06 - - - -0.6693 - 1.308 0.173 - 73.6 1 2 0 -0.0012 14 0 0 0 0.00E+00 0.00E+00 - - - 1.182 1 221125_WJC_METTL3_EV_vs_WT_F02.25073.25073.3 1.07E-07 14/52 R.ISLPLPNFSSLNLR.E "sp|P08670|VIME_HUMAN,tr|B0YJC4|B0YJC4_HUMAN" 2 1569.8879 2.17 23651 25073 3 1569.885306 524.3032 Vimentin OS=Homo sapiens OX=9606 GN=VIM PE=1 SV=4 9.75 3979.5 - 3.08E+06 - - - -1.6383 - 2.533 0.511 - 294 1 2 0 -0.0026 14 0 0 0 2.37E+08 1.09E+08 - - - 6.7064 1 221125_WJC_METTL3_EV_vs_WT_F02.25074.25074.3 5.61E-08 20/52 R.TGEAIVDAALSALR[166.11].Q sp|Q15084|PDIA6_HUMAN 1 1395.7597 -1 23652 25074 3 1395.756885 466.2605 Protein disulfide-isomerase A6 OS=Homo sapiens OX=9606 GN=PDIA6 PE=1 SV=1 4.37 3979.5 - 2.94E+06 - - - -2.0269 - 3.601 0.585 - 585.7 1 2 0 -0.0028 14 0 0 0 0.00E+00 0.00E+00 - - - 8.4663 1 221125_WJC_METTL3_EV_vs_WT_F02.25082.25082.3 3.74E-06 15/52 R.ISLPLPNFSSLNLR[166.11].E "sp|P08670|VIME_HUMAN,tr|B0YJC4|B0YJC4_HUMAN" 2 1579.8961 2.16 23659 25082 3 1579.894019 527.6393 Vimentin OS=Homo sapiens OX=9606 GN=VIM PE=1 SV=4 9.75 3980.4 - 2.20E+06 - - - -1.3476 - 2.606 0.493 - 329.1 1 2 0 -0.0021 14 0 0 0 2.34E+08 1.08E+08 - - - 6.5813 1 221125_WJC_METTL3_EV_vs_WT_F02.25084.25084.2 4.87E-13 18/42 K.LLDFGSLSNLQVTQPTVGMNFK[136.11].T "sp|P08708|RS17_HUMAN,tr|H3BNC9|H3BNC9_HUMAN" 2 2416.2552 1.2 23661 25084 2 2416.251952 1209.1349 40S ribosomal protein S17 OS=Homo sapiens OX=9606 GN=RPS17 PE=1 SV=2 5.84 3980.6 - 1.01E+07 - - - -1.3372 - 3.502 0.678 - 551 1 2 0 -0.0032 22 0 0 0 4.52E+07 3.77E+07 - - - 7.1291 0.8085 221125_WJC_METTL3_EV_vs_WT_F02.25087.25087.2 0.013 18-Jul K.FAAQELIEVK.R "sp|Q86U44|MTA70_HUMAN,tr|F5H6D8|F5H6D8_HUMAN,tr|H0YFV6|H0YFV6_HUMAN,tr|B4DTN4|B4DTN4_HUMAN" 4 1146.6285 0.02 23664 25087 2 1147.627816 574.3215 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 4.53 3980.7 - 2.77E+06 - - - 871.5473 - 1.605 0.328 - 93.4 1 2 0 0.9993 10 0 0 0 9.84E+06 4.34E+08 - - - 2.4704 0.9999 221125_WJC_METTL3_EV_vs_WT_F02.25093.25093.2 1.65E-05 26-Nov R.ISLPLPNFSSLNLR.E "sp|P08670|VIME_HUMAN,tr|B0YJC4|B0YJC4_HUMAN" 2 1569.8879 1.91 23668 25093 2 1569.886173 785.9512 Vimentin OS=Homo sapiens OX=9606 GN=VIM PE=1 SV=4 9.75 3981.4 - 4.49E+07 - - - -1.0861 - 2.124 0.535 - 228.5 1 2 0 -0.0017 14 0 0 0 1.36E+09 7.13E+08 - - - 4.8823 1 221125_WJC_METTL3_EV_vs_WT_F02.25094.25094.2 2.09E-11 16/26 R.MTDQEAIQDLWQWR[166.11].K "sp|P06748|NPM_HUMAN,tr|E5RI98|E5RI98_HUMAN,tr|A0A7I2V4G8|A0A7I2V4G8_HUMAN,tr|A0A7I2YQC0|A0A7I2YQC0_HUMAN,tr|A0A7I2V5J8|A0A7I2V5J8_HUMAN,tr|A0A7I2V5S2|A0A7I2V5S2_HUMAN" 6 1828.8442 0.94 23669 25094 2 1828.840877 915.4294 Nucleophosmin OS=Homo sapiens OX=9606 GN=NPM1 PE=1 SV=2 4.03 3981.5 - 8.76E+06 - - - -1.811 - 3.509 0.627 - 1031.1 1 2 0 -0.0033 14 0 0 0 9.11E+07 9.66E+07 - - - 6.8212 1 221125_WJC_METTL3_EV_vs_WT_F02.25095.25095.3 1.42E-07 16/52 R.MTDQEAIQDLWQWR[166.11].K "sp|P06748|NPM_HUMAN,tr|E5RI98|E5RI98_HUMAN,tr|A0A7I2V4G8|A0A7I2V4G8_HUMAN,tr|A0A7I2YQC0|A0A7I2YQC0_HUMAN,tr|A0A7I2V5J8|A0A7I2V5J8_HUMAN,tr|A0A7I2V5S2|A0A7I2V5S2_HUMAN" 6 1828.8442 0.79 23670 25095 3 1828.842932 610.622 Nucleophosmin OS=Homo sapiens OX=9606 GN=NPM1 PE=1 SV=2 4.03 3981.5 - 8.93E+06 - - - -0.6873 - 2.635 0.541 - 354.7 1 2 0 -0.0013 14 0 0 0 5.62E+07 7.15E+07 - - - 7.1461 0.9999 221125_WJC_METTL3_EV_vs_WT_F02.25096.25096.3 1.18E-07 18/64 K.LPNFGFVVFDDSEPVQR.L "sp|Q9UN86|G3BP2_HUMAN,tr|A0A7I2V647|A0A7I2V647_HUMAN,tr|A0A7I2YQD9|A0A7I2YQD9_HUMAN,tr|A0A7I2V382|A0A7I2V382_HUMAN,tr|A0A7I2V3P9|A0A7I2V3P9_HUMAN" 5 1964.9632 0.78 23671 25096 3 1964.956286 655.995 Ras GTPase-activating protein-binding protein 2 OS=Homo sapiens OX=9606 GN=G3BP2 PE=1 SV=2 4.03 3981.5 - 6.21E+06 - - - -3.5329 - 3.466 0.545 - 360.2 1 2 0 -0.0069 17 0 0 0 1.30E+08 1.67E+08 - - - 7.7545 1 221125_WJC_METTL3_EV_vs_WT_F02.25097.25097.3 0.000358 23/72 K.TLDSVTELASEVSQLNTIK.E "sp|Q15643|TRIPB_HUMAN,tr|H0YJ97|H0YJ97_HUMAN" 2 2047.0685 0.95 23672 25097 3 2047.068481 683.3634 Thyroid receptor-interacting protein 11 OS=Homo sapiens OX=9606 GN=TRIP11 PE=1 SV=3 4.14 3981.6 - 6.16E+06 - - - 0 - 3.857 0.565 - 547.2 1 2 0 0 19 0 0 0 3.66E+07 3.86E+07 - - - 8.1556 1 221125_WJC_METTL3_EV_vs_WT_F02.25098.25098.3 0.000206 21/72 K.TLDSVTELASEVSQLNTIK[136.11].E "sp|Q15643|TRIPB_HUMAN,tr|H0YJ97|H0YJ97_HUMAN" 2 2055.0827 0.94 23673 25098 3 2055.080065 686.0348 Thyroid receptor-interacting protein 11 OS=Homo sapiens OX=9606 GN=TRIP11 PE=1 SV=3 4.14 3981.6 - 6.14E+06 - - - -1.2729 - 3.38 0.532 - 393.2 1 2 0 -0.0026 19 0 0 0 3.66E+07 3.89E+07 - - - 7.4626 1 221125_WJC_METTL3_EV_vs_WT_F02.25099.25099.2 6.67E-13 19/32 K.LPNFGFVVFDDSEPVQR.L "sp|Q9UN86|G3BP2_HUMAN,tr|A0A7I2V647|A0A7I2V647_HUMAN,tr|A0A7I2YQD9|A0A7I2YQD9_HUMAN,tr|A0A7I2V382|A0A7I2V382_HUMAN,tr|A0A7I2V3P9|A0A7I2V3P9_HUMAN" 5 1964.9632 1.39 23674 25099 2 1964.959291 983.4889 Ras GTPase-activating protein-binding protein 2 OS=Homo sapiens OX=9606 GN=G3BP2 PE=1 SV=2 4.03 3981.7 - 5.99E+06 - - - -2.0036 - 3.488 0.68 - 1207.1 1 2 0 -0.0039 17 0 0 0 1.04E+08 7.49E+07 - - - 7.1338 1 221125_WJC_METTL3_EV_vs_WT_F02.25101.25101.3 7.89E-09 18/52 R.MTDQEAIQDLWQWR.K "sp|P06748|NPM_HUMAN,tr|E5RI98|E5RI98_HUMAN,tr|A0A7I2V4G8|A0A7I2V4G8_HUMAN,tr|A0A7I2YQC0|A0A7I2YQC0_HUMAN,tr|A0A7I2V5J8|A0A7I2V5J8_HUMAN,tr|A0A7I2V5S2|A0A7I2V5S2_HUMAN" 6 1818.8359 0.79 23676 25101 3 1818.834207 607.2859 Nucleophosmin OS=Homo sapiens OX=9606 GN=NPM1 PE=1 SV=2 4.03 3981.9 - 5.56E+06 - - - -0.9413 - 2.954 0.575 - 455.9 1 2 0 -0.0017 14 0 0 0 5.62E+07 7.15E+07 - - - 7.8287 1 221125_WJC_METTL3_EV_vs_WT_F02.25102.25102.2 5.04E-08 14/26 R.MTDQEAIQDLWQWR.K "sp|P06748|NPM_HUMAN,tr|E5RI98|E5RI98_HUMAN,tr|A0A7I2V4G8|A0A7I2V4G8_HUMAN,tr|A0A7I2YQC0|A0A7I2YQC0_HUMAN,tr|A0A7I2V5J8|A0A7I2V5J8_HUMAN,tr|A0A7I2V5S2|A0A7I2V5S2_HUMAN" 6 1818.8359 0.95 23677 25102 2 1818.834597 910.4252 Nucleophosmin OS=Homo sapiens OX=9606 GN=NPM1 PE=1 SV=2 4.03 3982 - 5.39E+06 - - - -0.7268 - 3.336 0.606 - 808.1 1 2 0 -0.0013 14 0 0 0 9.13E+07 9.66E+07 - - - 6.5398 1 221125_WJC_METTL3_EV_vs_WT_F02.25103.25103.3 7.78E-10 19/88 K.LISEVDSDGDGEISFQEFLTAAK.K sp|Q9NZT1|CALL5_HUMAN 1 2470.1751 14.47 23678 25103 3 2470.17278 824.399 Calmodulin-like protein 5 OS=Homo sapiens OX=9606 GN=CALML5 PE=1 SV=2 3.71 3982 - 3.92E+06 - - - -0.9518 - 3.492 0.661 - 484 1 2 0 -0.0024 23 0 0 0 2.61E+07 1.81E+06 - - - 8.8424 1 221125_WJC_METTL3_EV_vs_WT_F02.25105.25105.4 2.90E-12 31/126 R.KPLVIIAEDVDGEALSTLVLNR.L "sp|P10809|CH60_HUMAN,tr|A0A7I2V2X6|A0A7I2V2X6_HUMAN,tr|A0A7I2YQK6|A0A7I2YQK6_HUMAN,tr|A0A7I2V599|A0A7I2V599_HUMAN,tr|A0A7I2YQ71|A0A7I2YQ71_HUMAN,tr|A0A7I2V5M1|A0A7I2V5M1_HUMAN,tr|A0A7I2V5K3|A0A7I2V5K3_HUMAN" 7 2364.3264 1.33 23680 25105 4 2364.326351 592.0889 "60 kDa heat shock protein, mitochondrial OS=Homo sapiens OX=9606 GN=HSPD1 PE=1 SV=2" 4.32 3982.2 - 3.43E+06 - - - -0.0321 - 5.031 0.617 - 855.2 1 2 0 -0.0001 22 0 0 0 1.21E+08 9.07E+07 - - - 5.125 1 221125_WJC_METTL3_EV_vs_WT_F02.25106.25106.3 1.12E-09 26/80 R.QVTITGSAASISLAQYLINAR[166.11].L sp|Q15365|PCBP1_HUMAN 1 2186.1935 0.84 23681 25106 3 2186.19004 729.7384 Poly(rC)-binding protein 1 OS=Homo sapiens OX=9606 GN=PCBP1 PE=1 SV=2 8.75 3982.3 - 3.24E+06 - - - -1.5607 - 4.156 0.592 - 945.7 1 2 0 -0.0034 21 0 0 0 2.25E+07 2.68E+07 - - - 8.5546 0.9997 221125_WJC_METTL3_EV_vs_WT_F02.25107.25107.2 0.000865 13/22 K.TSDLIVLGLPWK[136.11].T "sp|Q13148|TADBP_HUMAN,tr|A0A087WX29|A0A087WX29_HUMAN,tr|G3V162|G3V162_HUMAN,tr|A0A087WV68|A0A087WV68_HUMAN,tr|A0A087WYY0|A0A087WYY0_HUMAN,tr|K7EN94|K7EN94_HUMAN,tr|A0A0A0N0M3|A0A0A0N0M3_HUMAN,tr|B1AKP7|B1AKP7_HUMAN,tr|K7EJM5|K7EJM5_HUMAN,tr|A0A087WXQ5|A0A087WXQ5_HUMAN,tr|A0A087X260|A0A087X260_HUMAN" 11 1348.7846 -1 23682 25107 2 1348.784468 675.3996 TAR DNA-binding protein 43 OS=Homo sapiens OX=9606 GN=TARDBP PE=1 SV=1 5.5 3982.4 - 3.14E+06 - - - -0.089 - 1.683 0.438 - 244.9 1 2 0 -0.0001 12 0 0 0 0.00E+00 0.00E+00 - - - 3.6458 0.9983 221125_WJC_METTL3_EV_vs_WT_F02.25114.25114.3 0.000116 15/72 G.VTIAQGGVLPNIQAVLLPK.K "sp|P16104|H2AX_HUMAN,sp|Q9BTM1|H2AJ_HUMAN,sp|Q93077|H2A1C_HUMAN,sp|Q99878|H2A1J_HUMAN,sp|Q16777|H2A2C_HUMAN,sp|Q8IUE6|H2A2B_HUMAN,sp|Q96QV6|H2A1A_HUMAN,sp|P04908|H2A1B_HUMAN,sp|P20671|H2A1D_HUMAN,sp|P0C0S8|H2A1_HUMAN,sp|Q6FI13|H2A2A_HUMAN,sp|Q96KK5|H2A1H_HUMAN,sp|Q7L7L0|H2A3_HUMAN,tr|A0A0U1RR32|A0A0U1RR32_HUMAN,tr|A0A0U1RRH7|A0A0U1RRH7_HUMAN,tr|H0YFX9|H0YFX9_HUMAN" 16 1930.1615 1.3 23687 25114 3 1930.159207 644.3945 Histone H2AX OS=Homo sapiens OX=9606 GN=H2AX PE=1 SV=2 8.72 3983.3 - 6.46E+07 - - - -1.2056 - 3.236 0.549 - 187.1 1 1 0 -0.0023 19 0 0 0 1.10E+09 8.47E+08 - - - 7.5453 0.9998 221125_WJC_METTL3_EV_vs_WT_F02.25117.25117.4 0.000914 22/126 K.TLTAIAVILTNFHDGRPLPIER.V "sp|Q14527|HLTF_HUMAN,tr|A0A0C4DGA6|A0A0C4DGA6_HUMAN" 2 2446.3696 1.42 23690 25117 4 2446.366586 612.5997 Helicase-like transcription factor OS=Homo sapiens OX=9606 GN=HLTF PE=1 SV=2 6.42 3983.4 - 3.16E+06 - - - -1.2439 - 2.935 0.379 - 221.4 1 2 0 -0.003 22 0 0 0 2.09E+07 1.47E+07 - - - 2.8763 1 221125_WJC_METTL3_EV_vs_WT_F02.25119.25119.3 4.65E-10 22/68 R.IIEENIPELLSLNLSNNR[166.11].L "sp|Q9UBU9|NXF1_HUMAN,tr|B4E227|B4E227_HUMAN,tr|E9PIN3|E9PIN3_HUMAN" 3 2090.1247 2.29 23692 25119 3 2090.13004 697.7155 Nuclear RNA export factor 1 OS=Homo sapiens OX=9606 GN=NXF1 PE=1 SV=1 4.25 3983.6 - 2.19E+06 - - - 2.553 - 3.853 0.57 - 646.7 1 2 0 0.0053 18 0 0 0 4.21E+07 1.84E+07 - - - 8.2522 0.9997 221125_WJC_METTL3_EV_vs_WT_F02.25120.25120.2 1.67E-08 22-Dec K.DTFNGNLPFLFK.V "sp|P34949|MPI_HUMAN,tr|H3BPB8|H3BPB8_HUMAN,tr|H3BP57|H3BP57_HUMAN,tr|H3BT48|H3BT48_HUMAN,tr|H3BPU7|H3BPU7_HUMAN,tr|H3BQX0|H3BQX0_HUMAN,tr|H3BUZ9|H3BUZ9_HUMAN,tr|H3BT46|H3BT46_HUMAN,tr|H3BPM5|H3BPM5_HUMAN,tr|B4DYB8|B4DYB8_HUMAN,tr|H3BPP3|H3BPP3_HUMAN,tr|H3BN01|H3BN01_HUMAN,tr|F5GX71|F5GX71_HUMAN,tr|H3BMZ9|H3BMZ9_HUMAN,tr|H3BNY8|H3BNY8_HUMAN" 15 1411.7136 1.43 23693 25120 2 1411.717172 706.8641 Mannose-6-phosphate isomerase OS=Homo sapiens OX=9606 GN=MPI PE=1 SV=2 5.84 3983.8 - 2.01E+06 - - - 2.5288 - 2.331 0.582 - 312.9 1 2 0 0.0036 12 0 0 0 1.61E+07 1.12E+07 - - - 5.5653 0.8022 221125_WJC_METTL3_EV_vs_WT_F02.25124.25124.4 0.0699 8/132 R.IFEDGNTVELLTGASLDRWSKEK[136.11].L "sp|Q8IV33|K0825_HUMAN,tr|A0A804HHT9|A0A804HHT9_HUMAN" 2 2615.3322 - 23695 25124 4 2615.325708 654.8403 Uncharacterized protein KIAA0825 OS=Homo sapiens OX=9606 GN=KIAA0825 PE=1 SV=3 4.51 3984.3 - 3.47E+07 - - - -2.5003 - 1.521 0.208 - 21.6 3 2 2 -0.0065 23 0 0 0 - - - - - 0.8068 1 221125_WJC_METTL3_EV_vs_WT_F02.25127.25127.3 3.96E-08 18/68 R.IIEENIPELLSLNLSNNR.L "sp|Q9UBU9|NXF1_HUMAN,tr|B4E227|B4E227_HUMAN,tr|E9PIN3|E9PIN3_HUMAN" 3 2080.1164 2.27 23698 25127 3 2080.119356 694.3794 Nuclear RNA export factor 1 OS=Homo sapiens OX=9606 GN=NXF1 PE=1 SV=1 4.25 3984.6 - 3.53E+06 - - - 1.4047 - 2.369 0.559 - 272.3 1 2 0 0.0029 18 0 0 0 4.72E+07 2.08E+07 - - - 6.9191 1 221125_WJC_METTL3_EV_vs_WT_F02.25129.25129.3 4.52E-06 13/52 K.TVEDLDGLIQQIYR[166.11].D "sp|Q9ULX6|AKP8L_HUMAN,tr|A0A7P0TAJ5|A0A7P0TAJ5_HUMAN,tr|A0A7P0TAE3|A0A7P0TAE3_HUMAN" 3 1671.8707 1.16 23700 25129 3 1671.871158 558.2975 A-kinase anchor protein 8-like OS=Homo sapiens OX=9606 GN=AKAP8L PE=1 SV=4 4.03 3984.8 - 2.16E+06 - - - 0.2614 - 2.283 0.489 - 242 1 2 0 0.0004 14 0 0 0 1.25E+07 1.07E+07 - - - 6.1855 0.9667 221125_WJC_METTL3_EV_vs_WT_F02.25133.25133.3 1.07E-09 21/76 A.GIGLLAAATQSLSMPASLGR.M "sp|P43243|MATR3_HUMAN,tr|A0A1B0GX04|A0A1B0GX04_HUMAN,tr|D6RBS2|D6RBS2_HUMAN,tr|A8MXP9|A8MXP9_HUMAN,tr|D6R991|D6R991_HUMAN,tr|D6REK4|D6REK4_HUMAN,tr|D6R9F3|D6R9F3_HUMAN,tr|A0A0R4J2E8|A0A0R4J2E8_HUMAN,tr|D6RB45|D6RB45_HUMAN,tr|D6RCM3|D6RCM3_HUMAN,tr|D6R8Z5|D6R8Z5_HUMAN,tr|D6REM6|D6REM6_HUMAN" 12 1913.0404 1.55 23702 25133 3 1914.041558 638.6874 Matrin-3 OS=Homo sapiens OX=9606 GN=MATR3 PE=1 SV=2 9.75 3985.3 - 2.27E+06 - - - 523.3167 - 3.876 0.596 - 393.8 1 1 0 1.0011 20 0 0 0 1.37E+07 8.87E+06 - - - 8.1943 1 221125_WJC_METTL3_EV_vs_WT_F02.25135.25135.3 1.84E-13 18/88 K.LC[160.03]YVALDFEQEMATAASSSSLEK[136.11].S "sp|Q6S8J3|POTEE_HUMAN,sp|P63261|ACTG_HUMAN,sp|P60709|ACTB_HUMAN,tr|A0A804GS07|A0A804GS07_HUMAN,tr|E7EVS6|E7EVS6_HUMAN,tr|A0A6Q8PFE4|A0A6Q8PFE4_HUMAN,tr|A0A2R8YEA7|A0A2R8YEA7_HUMAN,tr|A0A2R8Y793|A0A2R8Y793_HUMAN,tr|I3L4N8|I3L4N8_HUMAN" 9 2557.1808 1.53 23704 25135 3 2557.16787 853.4009 POTE ankyrin domain family member E OS=Homo sapiens OX=9606 GN=POTEE PE=2 SV=3 4 3985.4 - 3.38E+06 - - - -5.0395 - 3.751 0.726 - 490.3 1 2 0 -0.0129 23 0 0 0 2.61E+07 1.71E+07 - - - 9.732 1 221125_WJC_METTL3_EV_vs_WT_F02.25138.25138.3 1.53E-07 20/56 R.R[166.11]GVMLAVDAVIAELK[136.11].K "sp|P10809|CH60_HUMAN,tr|A0A7I2V2X6|A0A7I2V2X6_HUMAN,tr|A0A7I2V599|A0A7I2V599_HUMAN,tr|E7EXB4|E7EXB4_HUMAN,tr|A0A7I2YQ71|A0A7I2YQ71_HUMAN,tr|E7ESH4|E7ESH4_HUMAN,tr|A0A7I2V5M1|A0A7I2V5M1_HUMAN,tr|A0A7I2V5K3|A0A7I2V5K3_HUMAN,tr|A0A7I2V369|A0A7I2V369_HUMAN" 9 1601.9294 1.67 23706 25138 3 1601.930557 534.9837 "60 kDa heat shock protein, mitochondrial OS=Homo sapiens OX=9606 GN=HSPD1 PE=1 SV=2" 6.07 3985.8 - 2.36E+06 - - - 0.7416 - 3.482 0.557 - 606 1 2 0 0.0012 15 0 0 0 8.04E+07 4.82E+07 - - - 8.0051 1 221125_WJC_METTL3_EV_vs_WT_F02.25142.25142.3 1.19E-14 23/88 K.LC[160.03]YVALDFEQEMATAASSSSLEK.S "sp|Q6S8J3|POTEE_HUMAN,sp|P63261|ACTG_HUMAN,sp|P60709|ACTB_HUMAN,tr|A0A804GS07|A0A804GS07_HUMAN,tr|E7EVS6|E7EVS6_HUMAN,tr|A0A6Q8PFE4|A0A6Q8PFE4_HUMAN,tr|A0A2R8YEA7|A0A2R8YEA7_HUMAN,tr|A0A2R8Y793|A0A2R8Y793_HUMAN,tr|I3L4N8|I3L4N8_HUMAN" 9 2549.1666 1.53 23708 25142 3 2549.166284 850.7295 POTE ankyrin domain family member E OS=Homo sapiens OX=9606 GN=POTEE PE=2 SV=3 4 3986.2 - 6.20E+06 - - - -0.1071 - 4.378 0.731 - 847 1 2 0 -0.0003 23 0 0 0 2.61E+07 1.71E+07 - - - 10.1539 1 221125_WJC_METTL3_EV_vs_WT_F02.25143.25143.3 2.60E-08 18/56 R.RGVMLAVDAVIAELK.K "sp|P10809|CH60_HUMAN,tr|A0A7I2V2X6|A0A7I2V2X6_HUMAN,tr|A0A7I2V599|A0A7I2V599_HUMAN,tr|E7EXB4|E7EXB4_HUMAN,tr|A0A7I2YQ71|A0A7I2YQ71_HUMAN,tr|E7ESH4|E7ESH4_HUMAN,tr|A0A7I2V5M1|A0A7I2V5M1_HUMAN,tr|A0A7I2V5K3|A0A7I2V5K3_HUMAN,tr|A0A7I2V369|A0A7I2V369_HUMAN" 9 1583.9069 1.67 23709 25143 3 1583.905623 528.9762 "60 kDa heat shock protein, mitochondrial OS=Homo sapiens OX=9606 GN=HSPD1 PE=1 SV=2" 6.07 3986.2 - 9.68E+06 - - - -0.8056 - 3.583 0.499 - 466.5 1 2 0 -0.0013 15 0 0 0 8.04E+07 4.82E+07 - - - 7.4331 0.9999 221125_WJC_METTL3_EV_vs_WT_F02.25145.25145.2 1.27E-06 16/30 K.FQIGDYLDIAITPPNR.A "sp|O00422|SAP18_HUMAN,tr|H7BZW6|H7BZW6_HUMAN" 2 1831.9468 1.96 23711 25145 2 1831.946969 916.9807 Histone deacetylase complex subunit SAP18 OS=Homo sapiens OX=9606 GN=SAP18 PE=1 SV=1 4.21 3986.4 - 2.70E+06 - - - 0.0655 - 2.888 0.489 - 681.2 1 2 0 0.0001 16 0 0 0 3.19E+07 1.63E+07 - - - 5.2602 1 221125_WJC_METTL3_EV_vs_WT_F02.25148.25148.2 0.00131 15/24 R.DPTYFGPVLNYLR.H "sp|Q9NXV2|KCTD5_HUMAN,tr|H3BSS5|H3BSS5_HUMAN" 2 1553.7878 10.36 23714 25148 2 1553.785113 777.9012 BTB\POZ domain-containing protein KCTD5 OS=Homo sapiens OX=9606 GN=KCTD5 PE=1 SV=1 5.83 3986.8 - 2.16E+06 - - - -1.748 - 2.866 0.595 - 837.5 1 2 0 -0.0027 13 0 0 0 3.27E+07 3.16E+06 - - - 6.1372 1 221125_WJC_METTL3_EV_vs_WT_F02.25149.25149.3 0.00013 16/60 K.FQIGDYLDIAITPPNR[166.11].A "sp|O00422|SAP18_HUMAN,tr|H7BZW6|H7BZW6_HUMAN" 2 1841.9551 1.44 23715 25149 3 1841.957195 614.9923 Histone deacetylase complex subunit SAP18 OS=Homo sapiens OX=9606 GN=SAP18 PE=1 SV=1 4.21 3986.9 - 1.62E+06 - - - 1.1271 - 3.121 0.475 - 343.1 1 2 0 0.0021 16 0 0 0 2.06E+07 1.42E+07 - - - 6.7556 1 221125_WJC_METTL3_EV_vs_WT_F02.25150.25150.3 8.49E-11 19/76 K.ELMGEEILGASLSAPLTSYK.V "sp|Q9P2J5|SYLC_HUMAN,tr|A0A6I8PIV1|A0A6I8PIV1_HUMAN,tr|A0A6I8PRS0|A0A6I8PRS0_HUMAN,tr|A0A6I8PLB8|A0A6I8PLB8_HUMAN,tr|A0A6I8PIP7|A0A6I8PIP7_HUMAN,tr|A0A6I8PIT3|A0A6I8PIT3_HUMAN,tr|A0A6I8PTV8|A0A6I8PTV8_HUMAN,tr|A0A6I8PRU9|A0A6I8PRU9_HUMAN,tr|A0A6I8PS05|A0A6I8PS05_HUMAN,tr|B4DER1|B4DER1_HUMAN,tr|A0A6I8PL42|A0A6I8PL42_HUMAN" 11 2108.0711 0.31 23716 25150 3 2108.071846 703.6977 "Leucine--tRNA ligase, cytoplasmic OS=Homo sapiens OX=9606 GN=LARS1 PE=1 SV=2" 4.25 3987 - 1.52E+06 - - - 0.343 - 3.219 0.555 - 428.1 1 2 0 0.0007 20 0 0 0 5.01E+06 1.59E+07 - - - 7.5637 1 221125_WJC_METTL3_EV_vs_WT_F02.25151.25151.2 4.28E-09 16/38 A.GIGLLAAATQSLSMPASLGR[166.11].M "sp|P43243|MATR3_HUMAN,tr|A0A1B0GX04|A0A1B0GX04_HUMAN,tr|D6RBS2|D6RBS2_HUMAN,tr|A8MXP9|A8MXP9_HUMAN,tr|D6R991|D6R991_HUMAN,tr|D6REK4|D6REK4_HUMAN,tr|D6R9F3|D6R9F3_HUMAN,tr|A0A0R4J2E8|A0A0R4J2E8_HUMAN,tr|D6RB45|D6RB45_HUMAN,tr|D6RCM3|D6RCM3_HUMAN,tr|D6R8Z5|D6R8Z5_HUMAN,tr|D6REM6|D6REM6_HUMAN" 12 1923.0487 1.69 23717 25151 2 1923.048497 962.5316 Matrin-3 OS=Homo sapiens OX=9606 GN=MATR3 PE=1 SV=2 9.75 3987.2 - 1.15E+06 - - - -0.1066 - 3.352 0.569 - 794.8 1 1 0 -0.0002 20 0 0 0 7.62E+06 4.50E+06 - - - 6.2173 0.9999 221125_WJC_METTL3_EV_vs_WT_F02.25152.25152.3 2.76E-07 14/60 R.GMGGAFVLVLYDEIK[136.11]K[136.11].Y "sp|P12235|ADT1_HUMAN,sp|P05141|ADT2_HUMAN,sp|P12236|ADT3_HUMAN" 3 1754.9612 0.95 23718 25152 3 1754.966492 585.9943 ADP\ATP translocase 1 OS=Homo sapiens OX=9606 GN=SLC25A4 PE=1 SV=4 6.07 3987.3 - 1.07E+06 - - - 3.0274 - 2.673 0.464 - 232.5 1 2 0 0.0053 16 0 0 0 2.49E+07 2.61E+07 - - - 6.2344 0.9695 221125_WJC_METTL3_EV_vs_WT_F02.25153.25153.3 0.274 13/60 R.GMGGAFVLVLYDEIKK.Y "sp|P12235|ADT1_HUMAN,sp|P05141|ADT2_HUMAN,sp|P12236|ADT3_HUMAN" 3 1738.9328 0.95 23719 25153 3 1738.939603 580.6515 ADP\ATP translocase 1 OS=Homo sapiens OX=9606 GN=SLC25A4 PE=1 SV=4 6.07 3987.4 - 1.04E+06 - - - 3.9242 - 2.05 0.177 - 115.3 1 2 0 0.0068 16 0 0 0 2.47E+07 2.61E+07 - - - 2.3534 1 221125_WJC_METTL3_EV_vs_WT_F02.25157.25157.2 5.06E-06 17/30 R.FDQLFDDESDPFEVLK.A sp|Q8NC51|PAIRB_HUMAN 1 1942.8836 0.9 23721 25157 2 1942.882742 972.4491 Plasminogen activator inhibitor 1 RNA-binding protein OS=Homo sapiens OX=9606 GN=SERBP1 PE=1 SV=2 3.66 3988 - 1.73E+07 - - - -0.4622 - 3.349 0.61 - 950.2 1 2 0 -0.0009 16 0 0 0 8.82E+07 9.78E+07 - - - 6.5177 0.9999 221125_WJC_METTL3_EV_vs_WT_F02.25158.25158.2 3.99E-08 13/30 K.EFADSLGIPFLETSAK.N "sp|Q9H0U4|RAB1B_HUMAN,sp|P62820|RAB1A_HUMAN,sp|Q92928|RAB1C_HUMAN,tr|E9PLD0|E9PLD0_HUMAN,tr|E7END7|E7END7_HUMAN" 5 1723.8669 1.11 23722 25158 2 1723.865706 862.9407 Ras-related protein Rab-1B OS=Homo sapiens OX=9606 GN=RAB1B PE=1 SV=1 4.14 3988 - 6.70E+06 - - - -0.6741 - 2.759 0.559 - 286.6 1 2 0 -0.0012 16 0 0 0 1.05E+08 9.46E+07 - - - 5.6645 1 221125_WJC_METTL3_EV_vs_WT_F02.25159.25159.2 8.85E-12 16/30 R.FDQLFDDESDPFEVLK[136.11].A sp|Q8NC51|PAIRB_HUMAN 1 1950.8978 0.9 23723 25159 2 1950.896673 976.4562 Plasminogen activator inhibitor 1 RNA-binding protein OS=Homo sapiens OX=9606 GN=SERBP1 PE=1 SV=2 3.66 3988 - 2.19E+07 - - - -0.5982 - 3.148 0.679 - 752.9 1 2 0 -0.0012 16 0 0 0 8.82E+07 9.78E+07 - - - 6.8751 1 221125_WJC_METTL3_EV_vs_WT_F02.25160.25160.3 1.11E-10 20/64 K.ALQDEWDAVMLHSFTLR[166.11].Q "sp|Q9UMS4|PRP19_HUMAN,tr|F5GY56|F5GY56_HUMAN" 2 2040.9967 1.27 23724 25160 3 2040.996233 681.3395 Pre-mRNA-processing factor 19 OS=Homo sapiens OX=9606 GN=PRPF19 PE=1 SV=1 4.54 3988.1 - 7.67E+06 - - - -0.2126 - 3.951 0.637 - 684.6 1 2 0 -0.0004 17 0 0 0 3.25E+07 2.56E+07 - - - 9.1129 1 221125_WJC_METTL3_EV_vs_WT_F02.25161.25161.3 1.39E-07 Dec-60 R.FDQLFDDESDPFEVLK.A sp|Q8NC51|PAIRB_HUMAN 1 1942.8836 0.87 23725 25161 3 1942.885518 648.6352 Plasminogen activator inhibitor 1 RNA-binding protein OS=Homo sapiens OX=9606 GN=SERBP1 PE=1 SV=2 3.66 3988.1 - 5.26E+06 - - - 0.9666 - 2.746 0.566 - 200.9 1 2 0 0.0019 16 0 0 0 1.63E+07 1.87E+07 - - - 7.4417 0.9999 221125_WJC_METTL3_EV_vs_WT_F02.25163.25163.3 0.00138 13/60 K.FQIGDYLDIAITPPNR.A "sp|O00422|SAP18_HUMAN,tr|H7BZW6|H7BZW6_HUMAN" 2 1831.9468 1.44 23727 25163 3 1831.949063 611.6562 Histone deacetylase complex subunit SAP18 OS=Homo sapiens OX=9606 GN=SAP18 PE=1 SV=1 4.21 3988.2 - 3.35E+06 - - - 1.2086 - 2.593 0.413 - 202 1 2 0 0.0022 16 0 0 0 2.06E+07 1.42E+07 - - - 5.5887 0.9998 221125_WJC_METTL3_EV_vs_WT_F02.25164.25164.2 6.53E-05 20-Nov R.DLEDFFSAVGK[136.11].V "sp|Q86U06|RBM23_HUMAN,tr|G3XAP0|G3XAP0_HUMAN,tr|G3V546|G3V546_HUMAN,tr|G3V2B4|G3V2B4_HUMAN,tr|G3V225|G3V225_HUMAN" 5 1234.5961 1.4 23728 25164 2 1234.597665 618.3053 Probable RNA-binding protein 23 OS=Homo sapiens OX=9606 GN=RBM23 PE=1 SV=1 4.03 3988.3 - 2.73E+06 - - - 1.2522 - 2.295 0.53 - 271.2 1 2 0 0.0015 11 0 0 0 3.57E+07 2.54E+07 - - - 5.2024 1 221125_WJC_METTL3_EV_vs_WT_F02.25165.25165.2 1.09E-12 18/30 R.AGDPLDLVALAEQVQK.A sp|Q9BV19|CA050_HUMAN 1 1665.8938 1.95 23729 25165 2 1665.894928 833.9542 Uncharacterized protein C1orf50 OS=Homo sapiens OX=9606 GN=C1orf50 PE=1 SV=2 4.03 3988.4 - 2.58E+06 - - - 0.7065 - 3.459 0.655 - 1100.2 1 2 0 0.0012 16 0 0 0 1.31E+07 6.73E+06 - - - 6.9295 1 221125_WJC_METTL3_EV_vs_WT_F02.25166.25166.3 1.61E-14 19/72 R.SPNEEYTWEEDPLAGIIPR.T "sp|P52732|KIF11_HUMAN,tr|A0A7I2YQY4|A0A7I2YQY4_HUMAN,tr|A0A7I2V3A9|A0A7I2V3A9_HUMAN,tr|A0A7I2V3V3|A0A7I2V3V3_HUMAN" 4 2215.0433 6.53 23730 25166 3 2215.042886 739.3551 Kinesin-like protein KIF11 OS=Homo sapiens OX=9606 GN=KIF11 PE=1 SV=2 3.91 3988.5 - 1.72E+06 - - - -0.2 - 3.804 0.585 - 429.2 1 2 0 -0.0004 19 0 0 0 9.35E+07 1.43E+07 - - - 8.3445 1 221125_WJC_METTL3_EV_vs_WT_F02.25167.25167.2 2.38E-05 16/30 R.AGDPLDLVALAEQVQK[136.11].A sp|Q9BV19|CA050_HUMAN 1 1673.908 1.95 23731 25167 2 1673.906123 837.9613 Uncharacterized protein C1orf50 OS=Homo sapiens OX=9606 GN=C1orf50 PE=1 SV=2 4.03 3988.6 - 1.47E+06 - - - -1.0921 - 3.197 0.579 - 788.5 1 2 0 -0.0018 16 0 0 0 1.31E+07 6.73E+06 - - - 6.1743 1 221125_WJC_METTL3_EV_vs_WT_F02.25168.25168.2 8.21E-12 15/32 K.TYTDELTPIESAVSVFK[136.11].A sp|O75489|NDUS3_HUMAN 1 1906.9655 1.13 23732 25168 2 1906.965878 954.49 "NADH dehydrogenase [ubiquinone] iron-sulfur protein 3, mitochondrial OS=Homo sapiens OX=9606 GN=NDUFS3 PE=1 SV=1" 4.14 3988.7 - 1.41E+06 - - - 0.1846 - 3.318 0.679 - 502.2 1 2 0 0.0004 17 0 0 0 1.12E+07 9.96E+06 - - - 7.0047 1 221125_WJC_METTL3_EV_vs_WT_F02.25169.25169.4 0.000401 22/138 R.SVEGWILFVTGVHEEATEEDIHDK.F sp|Q9Y5S9|RBM8A_HUMAN 1 2739.3028 1.68 23733 25169 4 2739.3066 685.833 RNA-binding protein 8A OS=Homo sapiens OX=9606 GN=RBM8A PE=1 SV=1 4.24 3988.9 - 1.06E+06 - - - 1.3905 - 4.041 0.532 - 406.1 1 2 0 0.0038 24 0 0 0 4.35E+06 2.59E+06 - - - 4.3037 0.9957 221125_WJC_METTL3_EV_vs_WT_F02.25170.25170.3 6.31E-07 16/60 R.VLQC[160.03]QEEELTQMVSTM.S "sp|Q8N5Z5|KCD17_HUMAN,sp|Q9NXV2|KCTD5_HUMAN,sp|Q14681|KCTD2_HUMAN,tr|A0A087WX35|A0A087WX35_HUMAN,tr|H0Y731|H0Y731_HUMAN" 5 1924.858 - 23734 25170 3 1924.861273 642.6266 BTB\POZ domain-containing protein KCTD17 OS=Homo sapiens OX=9606 GN=KCTD17 PE=1 SV=3 3.67 3989 - 1.03E+06 - - - 1.6817 - 2.686 0.504 - 318.4 1 1 0 0.0032 16 0 0 0 - - - - - 6.6934 0.9326 221125_WJC_METTL3_EV_vs_WT_F02.25172.25172.3 0.437 Sep-60 K.SGTASVVC[160.03]LLNNFYPR.E "sp|P01834|IGKC_HUMAN,tr|A0A5H1ZRQ3|A0A5H1ZRQ3_HUMAN" 2 1796.888 0.83 23736 25172 3 1796.883766 599.9699 Immunoglobulin kappa constant OS=Homo sapiens OX=9606 GN=IGKC PE=1 SV=2 7.94 3989.2 - 777697 - - - -2.3307 - 1.924 0.083 - 66.7 1 2 0 -0.0042 16 0 0 0 1.21E+07 1.46E+07 - - - 1.1433 1 221125_WJC_METTL3_EV_vs_WT_F02.25174.25174.2 2.69E-08 17/40 K.SPPYTAFLGNLPYDVTEESIK.E "sp|P23588|IF4B_HUMAN,tr|E7EX17|E7EX17_HUMAN,tr|F8VSC7|F8VSC7_HUMAN,tr|F8VYE9|F8VYE9_HUMAN,tr|F8VRU1|F8VRU1_HUMAN,tr|F8VX11|F8VX11_HUMAN,tr|F8W0K0|F8W0K0_HUMAN,tr|F8VP89|F8VP89_HUMAN" 8 2340.1525 999 23738 25174 2 2340.155234 1171.0835 Eukaryotic translation initiation factor 4B OS=Homo sapiens OX=9606 GN=EIF4B PE=1 SV=2 4.14 3989.5 - 589404 - - - 1.1491 - 4.078 0.705 - 534.3 1 2 0 0.0027 21 0 0 0 3.68E+06 0.00E+00 - - - 7.703 0.9721 221125_WJC_METTL3_EV_vs_WT_F02.25176.25176.2 3.60E-05 Nov-32 K.ALQDEWDAVMLHSFTLR[166.11].Q "sp|Q9UMS4|PRP19_HUMAN,tr|F5GY56|F5GY56_HUMAN" 2 2040.9967 -1 23740 25176 2 2040.986812 1021.5056 Pre-mRNA-processing factor 19 OS=Homo sapiens OX=9606 GN=PRPF19 PE=1 SV=1 4.54 3989.8 - 425795 - - - -4.8285 - 2.33 0.11 - 420.7 1 2 0 -0.0099 17 0 0 0 0.00E+00 0.00E+00 - - - 1.93 0.9999 221125_WJC_METTL3_EV_vs_WT_F02.25179.25179.2 0.000621 20-Oct R.DLEDFFSAVGK.V "sp|Q86U06|RBM23_HUMAN,tr|G3XAP0|G3XAP0_HUMAN,tr|G3V546|G3V546_HUMAN,tr|G3V2B4|G3V2B4_HUMAN,tr|G3V225|G3V225_HUMAN" 5 1226.5819 1.41 23741 25179 2 1226.581592 614.2982 Probable RNA-binding protein 23 OS=Homo sapiens OX=9606 GN=RBM23 PE=1 SV=1 4.03 3990.2 - 1.03E+07 - - - -0.2666 - 1.986 0.52 - 197.7 1 2 0 -0.0003 11 0 0 0 3.59E+07 2.54E+07 - - - 4.7377 1 221125_WJC_METTL3_EV_vs_WT_F02.25180.25180.2 1.05E-10 18/30 K.EFADSLGIPFLETSAK[136.11].N "sp|Q9H0U4|RAB1B_HUMAN,sp|P62820|RAB1A_HUMAN,sp|Q92928|RAB1C_HUMAN,tr|E9PLD0|E9PLD0_HUMAN,tr|E7END7|E7END7_HUMAN" 5 1731.8811 1.11 23742 25180 2 1731.879764 866.9478 Ras-related protein Rab-1B OS=Homo sapiens OX=9606 GN=RAB1B PE=1 SV=1 4.14 3990.2 - 1.24E+07 - - - -0.7529 - 3.186 0.648 - 691.1 1 2 0 -0.0013 16 0 0 0 1.05E+08 9.46E+07 - - - 6.6756 1 221125_WJC_METTL3_EV_vs_WT_F02.25182.25182.3 1.24E-11 19/80 K.MSVQPTVSLGGFEITPPVVLR[166.11].L "sp|P06748|NPM_HUMAN,tr|E5RI98|E5RI98_HUMAN,tr|A0A7I2YQC0|A0A7I2YQC0_HUMAN,tr|A0A7I2V433|A0A7I2V433_HUMAN,tr|A0A7I2V2X9|A0A7I2V2X9_HUMAN,tr|A0A7I2V5J8|A0A7I2V5J8_HUMAN,tr|A0A7I2V5S2|A0A7I2V5S2_HUMAN,tr|A0A7I2V3U2|A0A7I2V3U2_HUMAN" 8 2236.2165 0.83 23744 25182 3 2236.217981 746.4128 Nucleophosmin OS=Homo sapiens OX=9606 GN=NPM1 PE=1 SV=2 5.75 3990.3 - 3.28E+06 - - - 0.6641 - 3.206 0.627 - 306.3 1 2 0 0.0015 21 0 0 0 1.01E+08 1.22E+08 - - - 8.3231 1 221125_WJC_METTL3_EV_vs_WT_F02.25184.25184.3 1.05E-10 17/84 R.LLQYSDALEHLLTTGQGVVLER.S "sp|O95299|NDUAA_HUMAN,tr|A0A7I2V4N8|A0A7I2V4N8_HUMAN,tr|A0A7I2V2N6|A0A7I2V2N6_HUMAN,tr|H7C1Y7|H7C1Y7_HUMAN,tr|A0A7I2V5B2|A0A7I2V5B2_HUMAN,tr|A0A7I2V419|A0A7I2V419_HUMAN,tr|A0A7I2V2W9|A0A7I2V2W9_HUMAN,tr|A0A7I2V2X3|A0A7I2V2X3_HUMAN,tr|A0A7I2YQU0|A0A7I2YQU0_HUMAN,tr|H7C2X4|H7C2X4_HUMAN,tr|A0A7I2V438|A0A7I2V438_HUMAN,tr|Q8N1B9|Q8N1B9_HUMAN,tr|E7ESZ7|E7ESZ7_HUMAN,tr|C9J6X0|C9J6X0_HUMAN,tr|A0A7I2V3H5|A0A7I2V3H5_HUMAN,tr|A0A7I2V5L0|A0A7I2V5L0_HUMAN,tr|A0A087WXC5|A0A087WXC5_HUMAN,tr|A0A7I2V458|A0A7I2V458_HUMAN,tr|A0A7I2V2F6|A0A7I2V2F6_HUMAN,tr|A0A7I2V594|A0A7I2V594_HUMAN,tr|A0A7I2V327|A0A7I2V327_HUMAN,tr|A0A7I2V5U7|A0A7I2V5U7_HUMAN,tr|A0A7I2V3D4|A0A7I2V3D4_HUMAN,tr|A0A7I2V2I6|A0A7I2V2I6_HUMAN" 24 2454.3118 1.3 23746 25184 3 2454.311777 819.1112 "NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 10, mitochondrial OS=Homo sapiens OX=9606 GN=NDUFA10 PE=1 SV=1" 4.65 3990.4 - 3.13E+06 - - - -0.0253 - 3.52 0.623 - 245.4 1 2 0 -0.0001 22 0 0 0 1.11E+07 8.55E+06 - - - 8.4694 0.9999 221125_WJC_METTL3_EV_vs_WT_F02.25185.25185.3 2.00E-05 Oct-60 R.FDQLFDDESDPFEVLK[136.11].A sp|Q8NC51|PAIRB_HUMAN 1 1950.8978 0.87 23747 25185 3 1950.897101 651.3066 Plasminogen activator inhibitor 1 RNA-binding protein OS=Homo sapiens OX=9606 GN=SERBP1 PE=1 SV=2 3.66 3990.5 - 2.90E+06 - - - -0.3788 - 1.826 0.504 - 104 1 2 0 -0.0007 16 0 0 0 1.63E+07 1.87E+07 - - - 5.7039 1 221125_WJC_METTL3_EV_vs_WT_F02.25186.25186.3 4.62E-10 17/80 K.MSVQPTVSLGGFEITPPVVLR.L "sp|P06748|NPM_HUMAN,tr|E5RI98|E5RI98_HUMAN,tr|A0A7I2YQC0|A0A7I2YQC0_HUMAN,tr|A0A7I2V433|A0A7I2V433_HUMAN,tr|A0A7I2V2X9|A0A7I2V2X9_HUMAN,tr|A0A7I2V5J8|A0A7I2V5J8_HUMAN,tr|A0A7I2V5S2|A0A7I2V5S2_HUMAN,tr|A0A7I2V3U2|A0A7I2V3U2_HUMAN" 8 2226.2082 0.83 23748 25186 3 2226.211053 743.0767 Nucleophosmin OS=Homo sapiens OX=9606 GN=NPM1 PE=1 SV=2 5.75 3990.6 - 2.84E+06 - - - 1.2699 - 3.166 0.567 - 244.8 1 2 0 0.0028 21 0 0 0 1.01E+08 1.22E+08 - - - 7.6237 0.9999 221125_WJC_METTL3_EV_vs_WT_F02.25187.25187.3 0.000419 Dec-60 K.EFADSLGIPFLETSAK.N "sp|Q9H0U4|RAB1B_HUMAN,sp|P62820|RAB1A_HUMAN,sp|Q92928|RAB1C_HUMAN,tr|E9PLD0|E9PLD0_HUMAN,tr|E7END7|E7END7_HUMAN" 5 1723.8669 1.11 23749 25187 3 1723.866722 575.6296 Ras-related protein Rab-1B OS=Homo sapiens OX=9606 GN=RAB1B PE=1 SV=1 4.14 3990.6 - 2.80E+06 - - - -0.0847 - 2.255 0.433 - 220.5 1 2 0 -0.0001 16 0 0 0 1.65E+07 1.48E+07 - - - 5.4539 1 221125_WJC_METTL3_EV_vs_WT_F02.25188.25188.2 4.87E-17 22/36 R.SPNEEYTWEEDPLAGIIPR.T "sp|P52732|KIF11_HUMAN,tr|A0A7I2YQY4|A0A7I2YQY4_HUMAN,tr|A0A7I2V3A9|A0A7I2V3A9_HUMAN,tr|A0A7I2V3V3|A0A7I2V3V3_HUMAN" 4 2215.0433 5.42 23750 25188 2 2215.044738 1108.5289 Kinesin-like protein KIF11 OS=Homo sapiens OX=9606 GN=KIF11 PE=1 SV=2 3.91 3990.7 - 2.72E+06 - - - 0.6361 - 4.082 0.728 - 1064.6 1 2 0 0.0014 19 0 0 0 4.98E+07 9.19E+06 - - - 7.8757 0.9999 221125_WJC_METTL3_EV_vs_WT_F02.25189.25189.3 5.50E-09 21/100 K.VGDAIPAVEVFEGEPGNKVNLAELFK.G sp|P30044|PRDX5_HUMAN 1 2741.4276 1.84 23751 25189 3 2741.432101 914.8165 "Peroxiredoxin-5, mitochondrial OS=Homo sapiens OX=9606 GN=PRDX5 PE=1 SV=4" 4.25 3990.8 - 1.94E+06 - - - 1.6429 - 3.492 0.572 - 324.7 1 2 1 0.0045 26 0 0 0 1.61E+07 8.75E+06 - - - 7.7929 0.9949 221125_WJC_METTL3_EV_vs_WT_F02.25190.25190.4 1.01E-08 24/120 N.WITLGNQLDGIHLLDPDVVAR[166.11].F sp|Q86U44|MTA70_HUMAN 1 2354.2622 -1 23752 25190 4 2354.261763 589.5728 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 4.41 3990.9 - 1.72E+06 - - - -0.1856 - 3.64 0.472 - 416.5 1 1 0 -0.0004 21 0 0 0 0.00E+00 0.00E+00 - - - 3.7613 1 221125_WJC_METTL3_EV_vs_WT_F02.25191.25191.3 1.67E-08 24/84 R.AEPYC[160.03]SVLPGFTFIQHLPLSER[166.11].L "sp|Q9BUJ2|HNRL1_HUMAN,tr|M0QYZ0|M0QYZ0_HUMAN,tr|A0A0A0MRA5|A0A0A0MRA5_HUMAN,tr|M0R3F1|M0R3F1_HUMAN,tr|B7Z4B8|B7Z4B8_HUMAN" 5 2570.2867 1.28 23753 25191 3 2570.28432 857.7695 Heterogeneous nuclear ribonucleoprotein U-like protein 1 OS=Homo sapiens OX=9606 GN=HNRNPUL1 PE=1 SV=2 5.4 3991 - 1.67E+06 - - - -0.9264 - 3.361 0.587 - 616.4 1 2 0 -0.0024 22 0 0 0 1.10E+07 8.57E+06 - - - 7.9578 1 221125_WJC_METTL3_EV_vs_WT_F02.25192.25192.2 3.15E-09 30-Dec R.VLQC[160.03]QEEELTQMVSTM.S "sp|Q8N5Z5|KCD17_HUMAN,sp|Q9NXV2|KCTD5_HUMAN,sp|Q14681|KCTD2_HUMAN,tr|A0A087WX35|A0A087WX35_HUMAN,tr|H0Y731|H0Y731_HUMAN" 5 1924.858 - 23754 25192 2 1924.858442 963.4363 BTB\POZ domain-containing protein KCTD17 OS=Homo sapiens OX=9606 GN=KCTD17 PE=1 SV=3 3.67 3991.1 - 1.66E+06 - - - 0.2109 - 2.464 0.638 - 473.6 1 1 0 0.0004 16 0 0 0 - - - - - 5.9702 1 221125_WJC_METTL3_EV_vs_WT_F02.25193.25193.3 2.69E-11 17/80 K.WGDAGAEYVVESTGVFTTMEK.A "sp|P04406|G3P_HUMAN,tr|E7EUT5|E7EUT5_HUMAN" 2 2276.0307 1.23 23755 25193 3 2276.034078 759.6842 Glyceraldehyde-3-phosphate dehydrogenase OS=Homo sapiens OX=9606 GN=GAPDH PE=1 SV=3 4 3991.2 - 1.54E+06 - - - 1.4776 - 3.534 0.587 - 251 1 2 0 0.0034 21 0 0 0 2.15E+07 1.75E+07 - - - 8.1102 0.9991 221125_WJC_METTL3_EV_vs_WT_F02.25195.25195.3 0.000293 14/100 K.VGDAIPAVEVFEGEPGNK[136.11]VNLAELFK[136.11].G sp|P30044|PRDX5_HUMAN 1 2757.456 1.84 23757 25195 3 2757.46019 920.1593 "Peroxiredoxin-5, mitochondrial OS=Homo sapiens OX=9606 GN=PRDX5 PE=1 SV=4" 4.25 3991.5 - 1.23E+06 - - - 1.5206 - 2.715 0.366 - 127.4 1 2 1 0.0042 26 0 0 0 1.61E+07 8.75E+06 - - - 4.9172 0.9999 221125_WJC_METTL3_EV_vs_WT_F02.25196.25196.3 1.35E-07 15/64 K.ENLELILTQSVENVGVR.G "sp|Q9BYD2|RM09_HUMAN,tr|A0A1W2PPE5|A0A1W2PPE5_HUMAN,tr|Q5SZR1|Q5SZR1_HUMAN,tr|A0A1W2PS92|A0A1W2PS92_HUMAN,tr|A0A1W2PQB6|A0A1W2PQB6_HUMAN" 5 1912.0266 2.01 23758 25196 3 1912.021424 638.3495 "39S ribosomal protein L9, mitochondrial OS=Homo sapiens OX=9606 GN=MRPL9 PE=1 SV=2" 4.25 3991.5 - 1.17E+06 - - - -2.6841 - 2.997 0.485 - 326.3 1 2 0 -0.0051 17 0 0 0 1.21E+07 6.03E+06 - - - 6.7187 1 221125_WJC_METTL3_EV_vs_WT_F02.25200.25200.3 4.90E-12 27/84 R.K[136.11]PLVIIAEDVDGEALSTLVLNR[166.11].L "sp|P10809|CH60_HUMAN,tr|A0A7I2V2X6|A0A7I2V2X6_HUMAN,tr|A0A7I2YQK6|A0A7I2YQK6_HUMAN,tr|A0A7I2V599|A0A7I2V599_HUMAN,tr|A0A7I2YQ71|A0A7I2YQ71_HUMAN,tr|A0A7I2V5M1|A0A7I2V5M1_HUMAN,tr|A0A7I2V5K3|A0A7I2V5K3_HUMAN" 7 2382.3489 1.19 23761 25200 3 2382.34833 795.1236 "60 kDa heat shock protein, mitochondrial OS=Homo sapiens OX=9606 GN=HSPD1 PE=1 SV=2" 4.32 3992 - 1.32E+07 - - - -0.238 - 5.125 0.711 - 936.2 1 2 0 -0.0006 22 0 0 0 1.07E+08 8.98E+07 - - - 10.341 1 221125_WJC_METTL3_EV_vs_WT_F02.25201.25201.2 2.18E-09 18/40 K.MSVQPTVSLGGFEITPPVVLR.L "sp|P06748|NPM_HUMAN,tr|E5RI98|E5RI98_HUMAN,tr|A0A7I2YQC0|A0A7I2YQC0_HUMAN,tr|A0A7I2V433|A0A7I2V433_HUMAN,tr|A0A7I2V2X9|A0A7I2V2X9_HUMAN,tr|A0A7I2V5J8|A0A7I2V5J8_HUMAN,tr|A0A7I2V5S2|A0A7I2V5S2_HUMAN,tr|A0A7I2V3U2|A0A7I2V3U2_HUMAN" 8 2226.2082 0.87 23762 25201 2 2226.207221 1114.1114 Nucleophosmin OS=Homo sapiens OX=9606 GN=NPM1 PE=1 SV=2 5.75 3992.2 - 2.02E+06 - - - -0.4514 - 3.056 0.611 - 662.5 1 2 0 -0.001 21 0 0 0 3.52E+07 4.06E+07 - - - 6.3 1 221125_WJC_METTL3_EV_vs_WT_F02.25202.25202.2 1.97E-07 13/30 K.AAGVNVEPFWPGLFAK.A sp|P05386|RLA1_HUMAN 1 1701.8879 1.51 23763 25202 2 1701.887953 851.9512 60S acidic ribosomal protein P1 OS=Homo sapiens OX=9606 GN=RPLP1 PE=1 SV=1 6.05 3992.2 - 1.94E+07 - - - 0.0441 - 2.827 0.624 - 366.4 1 2 0 0.0001 16 0 0 0 2.24E+08 1.48E+08 - - - 6.2048 1 221125_WJC_METTL3_EV_vs_WT_F02.25203.25203.3 3.88E-08 20/68 K.ETDLLLDDSLVSIFGNRR.L sp|P30044|PRDX5_HUMAN 1 2062.0695 1.39 23764 25203 3 2062.070159 688.3638 "Peroxiredoxin-5, mitochondrial OS=Homo sapiens OX=9606 GN=PRDX5 PE=1 SV=4" 4.23 3992.2 - 9.67E+06 - - - 0.3273 - 3.099 0.571 - 436.9 1 2 0 0.0007 18 0 0 0 2.49E+07 1.80E+07 - - - 7.7224 1 221125_WJC_METTL3_EV_vs_WT_F02.25205.25205.3 1.39E-09 26/72 K.IAALQAFADQLIAAGHYAK.G "sp|Q13813|SPTN1_HUMAN,tr|A0A0D9SF54|A0A0D9SF54_HUMAN,tr|A0A0D9SGF6|A0A0D9SGF6_HUMAN" 3 1971.0578 -1 23766 25205 3 1971.057335 658.0265 "Spectrin alpha chain, non-erythrocytic 1 OS=Homo sapiens OX=9606 GN=SPTAN1 PE=1 SV=3" 6.74 3992.4 - 3.28E+06 - - - -0.2344 - 4.232 0.594 - 876.8 1 2 0 -0.0005 19 0 0 0 0.00E+00 0.00E+00 - - - 8.7068 1 221125_WJC_METTL3_EV_vs_WT_F02.25206.25206.3 2.84E-07 19/60 K.AAGVNVEPFWPGLFAK[136.11].A sp|P05386|RLA1_HUMAN 1 1709.9021 1.59 23767 25206 3 1709.901674 570.9746 60S acidic ribosomal protein P1 OS=Homo sapiens OX=9606 GN=RPLP1 PE=1 SV=1 6.05 3992.4 - 2.84E+06 - - - -0.2363 - 2.963 0.55 - 263.8 1 2 0 -0.0004 16 0 0 0 3.95E+07 2.48E+07 - - - 7.4589 1 221125_WJC_METTL3_EV_vs_WT_F02.25209.25209.2 1.27E-12 23/40 K.MSVQPTVSLGGFEITPPVVLR[166.11].L "sp|P06748|NPM_HUMAN,tr|E5RI98|E5RI98_HUMAN,tr|A0A7I2YQC0|A0A7I2YQC0_HUMAN,tr|A0A7I2V433|A0A7I2V433_HUMAN,tr|A0A7I2V2X9|A0A7I2V2X9_HUMAN,tr|A0A7I2V5J8|A0A7I2V5J8_HUMAN,tr|A0A7I2V5S2|A0A7I2V5S2_HUMAN,tr|A0A7I2V3U2|A0A7I2V3U2_HUMAN" 8 2236.2165 0.87 23770 25209 2 2236.216171 1119.1155 Nucleophosmin OS=Homo sapiens OX=9606 GN=NPM1 PE=1 SV=2 5.75 3992.6 - 2.07E+06 - - - -0.1453 - 3.858 0.739 - 1486.5 1 2 0 -0.0003 21 0 0 0 3.52E+07 4.06E+07 - - - 7.8186 1 221125_WJC_METTL3_EV_vs_WT_F02.25210.25210.2 6.20E-13 23/36 R.SPNEEYTWEEDPLAGIIPR[166.11].T "sp|P52732|KIF11_HUMAN,tr|A0A7I2YQY4|A0A7I2YQY4_HUMAN,tr|A0A7I2V3A9|A0A7I2V3A9_HUMAN,tr|A0A7I2V3V3|A0A7I2V3V3_HUMAN" 4 2225.0516 5.42 23771 25210 2 2225.050669 1113.5331 Kinesin-like protein KIF11 OS=Homo sapiens OX=9606 GN=KIF11 PE=1 SV=2 3.91 3992.7 - 2.02E+06 - - - -0.418 - 3.687 0.691 - 1225.1 1 2 0 -0.0009 19 0 0 0 4.98E+07 9.19E+06 - - - 7.3524 1 221125_WJC_METTL3_EV_vs_WT_F02.25212.25212.3 3.79E-13 27/76 R.LIDVPDPVPALDLGQQLQLK.V "sp|Q13948|CASP_HUMAN,sp|P39880|CUX1_HUMAN,tr|A0A2R8Y852|A0A2R8Y852_HUMAN,tr|A0A2R8YDI1|A0A2R8YDI1_HUMAN" 4 2171.2202 1.35 23773 25212 3 2171.220322 724.7473 Protein CASP OS=Homo sapiens OX=9606 GN=CUX1 PE=1 SV=2 3.93 3993 - 1.08E+06 - - - 0.0695 - 4.049 0.64 - 824.6 1 2 0 0.0002 20 0 0 0 2.41E+07 1.79E+07 - - - 9.068 1 221125_WJC_METTL3_EV_vs_WT_F02.25213.25213.3 6.45E-12 24/76 R.LIDVPDPVPALDLGQQLQLK[136.11].V "sp|Q13948|CASP_HUMAN,sp|P39880|CUX1_HUMAN,tr|A0A2R8Y852|A0A2R8Y852_HUMAN,tr|A0A2R8YDI1|A0A2R8YDI1_HUMAN" 4 2179.2344 1.3 23774 25213 3 2179.236408 727.4187 Protein CASP OS=Homo sapiens OX=9606 GN=CUX1 PE=1 SV=2 3.93 3993.1 - 930857 - - - 0.9347 - 3.85 0.641 - 771.1 1 2 0 0.002 20 0 0 0 2.41E+07 1.85E+07 - - - 8.9564 0.992 221125_WJC_METTL3_EV_vs_WT_F02.25214.25214.2 5.33E-05 18/28 K.NILQELLGQPVQRPA.S sp|Q9NRA8|4ET_HUMAN 1 1674.9417 -1 23775 25214 2 1674.944007 838.4781 Eukaryotic translation initiation factor 4E transporter OS=Homo sapiens OX=9606 GN=EIF4ENIF1 PE=1 SV=2 6 3993.2 - 769315 - - - 1.375 - 3.271 0.499 - 1148.9 1 1 0 0.0023 15 0 0 0 0.00E+00 0.00E+00 - - - 5.6395 1 221125_WJC_METTL3_EV_vs_WT_F02.25215.25215.4 2.17E-10 31/180 K.AVTPPMPLLTPATPGGLPPAAAVAAAAATAK.L "sp|Q9UHX1|PUF60_HUMAN,tr|A0A0J9YYL3|A0A0J9YYL3_HUMAN,tr|A0A0J9YWM1|A0A0J9YWM1_HUMAN,tr|H0YEM1|H0YEM1_HUMAN,tr|A0A0J9YVR6|A0A0J9YVR6_HUMAN,tr|A0A0J9YXX5|A0A0J9YXX5_HUMAN,tr|A0A0J9YXJ8|A0A0J9YXJ8_HUMAN,tr|E9PQ56|E9PQ56_HUMAN,tr|H0YCP8|H0YCP8_HUMAN,tr|A0A0J9YVP6|A0A0J9YVP6_HUMAN" 10 2793.5463 1.88 23776 25215 4 2793.542852 699.3938 Poly(U)-binding-splicing factor PUF60 OS=Homo sapiens OX=9606 GN=PUF60 PE=1 SV=1 8.8 3993.3 - 642762 - - - -1.2246 - 4.791 0.575 - 401.7 1 2 0 -0.0034 31 0 0 0 4.95E+06 2.63E+06 - - - 4.706 1 221125_WJC_METTL3_EV_vs_WT_F02.25220.25220.4 7.85E-05 19/126 R.K[136.11]PLVIIAEDVDGEALSTLVLNR[166.11].L "sp|P10809|CH60_HUMAN,tr|A0A7I2V2X6|A0A7I2V2X6_HUMAN,tr|A0A7I2YQK6|A0A7I2YQK6_HUMAN,tr|A0A7I2V599|A0A7I2V599_HUMAN,tr|A0A7I2YQ71|A0A7I2YQ71_HUMAN,tr|A0A7I2V5M1|A0A7I2V5M1_HUMAN,tr|A0A7I2V5K3|A0A7I2V5K3_HUMAN" 7 2382.3489 2.29 23780 25220 4 2382.345636 596.5945 "60 kDa heat shock protein, mitochondrial OS=Homo sapiens OX=9606 GN=HSPD1 PE=1 SV=2" 4.32 3993.9 - 6.47E+06 - - - -1.3688 - 3.163 0.484 - 145.9 1 2 0 -0.0033 22 0 0 0 1.54E+07 6.74E+06 - - - 3.8146 1 221125_WJC_METTL3_EV_vs_WT_F02.25221.25221.2 0.000779 16/30 K.AAGVNVEPFWPGLFAK[136.11].A sp|P05386|RLA1_HUMAN 1 1709.9021 1.51 23781 25221 2 1709.900369 855.9583 60S acidic ribosomal protein P1 OS=Homo sapiens OX=9606 GN=RPLP1 PE=1 SV=1 6.05 3993.9 - 4.02E+07 - - - -0.9995 - 3.087 0.56 - 621.8 1 2 0 -0.0017 16 0 0 0 2.24E+08 1.48E+08 - - - 5.9479 1 221125_WJC_METTL3_EV_vs_WT_F02.25223.25223.3 3.29E-05 14/60 K.AAGVNVEPFWPGLFAK.A sp|P05386|RLA1_HUMAN 1 1701.8879 1.59 23783 25223 3 1701.887219 568.3032 60S acidic ribosomal protein P1 OS=Homo sapiens OX=9606 GN=RPLP1 PE=1 SV=1 6.05 3994 - 1.43E+07 - - - -0.3872 - 2.863 0.501 - 173.8 1 2 0 -0.0007 16 0 0 0 3.95E+07 2.48E+07 - - - 6.8244 0.9998 221125_WJC_METTL3_EV_vs_WT_F02.25224.25224.2 2.89E-05 18-Nov K.FAAQELIEVK[136.11].R "sp|Q86U44|MTA70_HUMAN,tr|F5H6D8|F5H6D8_HUMAN,tr|H0YFV6|H0YFV6_HUMAN,tr|B4DTN4|B4DTN4_HUMAN" 4 1154.6427 0.01 23784 25224 2 1154.641035 578.3286 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 4.53 3994 - 1.27E+07 - - - -1.4204 - 2.159 0.505 - 313.1 1 2 0 -0.0016 10 0 0 0 7.73E+05 5.68E+07 - - - 4.9187 1 221125_WJC_METTL3_EV_vs_WT_F02.25225.25225.3 9.55E-05 26/120 K.AVTPPMPLLTPATPGGLPPAAAVAAAAATAK.L "sp|Q9UHX1|PUF60_HUMAN,tr|A0A0J9YYL3|A0A0J9YYL3_HUMAN,tr|A0A0J9YWM1|A0A0J9YWM1_HUMAN,tr|H0YEM1|H0YEM1_HUMAN,tr|A0A0J9YVR6|A0A0J9YVR6_HUMAN,tr|A0A0J9YXX5|A0A0J9YXX5_HUMAN,tr|A0A0J9YXJ8|A0A0J9YXJ8_HUMAN,tr|E9PQ56|E9PQ56_HUMAN,tr|H0YCP8|H0YCP8_HUMAN,tr|A0A0J9YVP6|A0A0J9YVP6_HUMAN" 10 2793.5463 1.37 23785 25225 3 2793.545958 932.1894 Poly(U)-binding-splicing factor PUF60 OS=Homo sapiens OX=9606 GN=PUF60 PE=1 SV=1 8.8 3994.1 - 4.64E+06 - - - -0.1128 - 4.246 0.552 - 316.2 1 2 0 -0.0003 31 0 0 0 1.39E+07 1.02E+07 - - - 8.0208 0.9996 221125_WJC_METTL3_EV_vs_WT_F02.25226.25226.2 7.93E-07 17/34 K.TSTVDLPIENQLLWQIDR[166.11].E sp|P34932|HSP74_HUMAN 1 2150.1247 0.01 23786 25226 2 2150.119523 1076.0696 Heat shock 70 kDa protein 4 OS=Homo sapiens OX=9606 GN=HSPA4 PE=1 SV=4 4.03 3994.2 - 4.34E+06 - - - -2.4096 - 3.294 0.36 - 578.7 1 2 0 -0.0052 18 0 0 0 2.42E+05 2.48E+07 - - - 4.6292 1 221125_WJC_METTL3_EV_vs_WT_F02.25230.25230.3 1.67E-12 22/64 R.SLLKEEDPAVLISEVLR.R "sp|Q9H019|MFR1L_HUMAN,tr|E9PLD2|E9PLD2_HUMAN" 2 1910.0724 2.66 23790 25230 3 1910.072718 637.6981 Mitochondrial fission regulator 1-like OS=Homo sapiens OX=9606 GN=MTFR1L PE=1 SV=2 4.41 3994.5 - 2.42E+06 - - - 0.1435 - 3.786 0.639 - 754.7 1 2 1 0.0003 17 0 0 0 7.52E+06 2.83E+06 - - - 9.0274 0.9999 221125_WJC_METTL3_EV_vs_WT_F02.25232.25232.3 7.01E-06 Oct-92 K.ITGMLLEIDNSELLYMLESPESLR.S sp|Q9H361|PABP3_HUMAN 1 2765.3867 -1 23792 25232 3 2765.384155 922.8028 Polyadenylate-binding protein 3 OS=Homo sapiens OX=9606 GN=PABPC3 PE=1 SV=2 3.91 3994.7 - 2.22E+06 - - - -0.9275 - 2.408 0.437 - 76 1 2 0 -0.0026 24 0 0 0 0.00E+00 0.00E+00 - - - 5.4525 0.9908 221125_WJC_METTL3_EV_vs_WT_F02.25234.25234.3 0.00168 Dec-56 K.NILQELLGQPVQRPA.S sp|Q9NRA8|4ET_HUMAN 1 1674.9417 -1 23794 25234 3 1674.941218 559.3212 Eukaryotic translation initiation factor 4E transporter OS=Homo sapiens OX=9606 GN=EIF4ENIF1 PE=1 SV=2 6 3994.8 - 2.01E+06 - - - -0.2902 - 2.383 0.404 - 171.1 1 1 0 -0.0005 15 0 0 0 0.00E+00 0.00E+00 - - - 5.3099 0.9614 221125_WJC_METTL3_EV_vs_WT_F02.25235.25235.2 5.24E-05 14/32 K.APPNLPPGVPPLLPNPY.L "sp|Q14157|UBP2L_HUMAN,tr|F8W726|F8W726_HUMAN,tr|H7C2T8|H7C2T8_HUMAN,tr|H0Y5H6|H0Y5H6_HUMAN" 4 1751.961 - 23795 25235 2 1751.955483 876.9878 Ubiquitin-associated protein 2-like OS=Homo sapiens OX=9606 GN=UBAP2L PE=1 SV=2 5.57 3994.9 - 1.69E+06 - - - -3.1736 - 2.374 0.48 - 293.4 1 1 0 -0.0056 17 0 0 0 - - - - - 4.7101 0.9998 221125_WJC_METTL3_EV_vs_WT_F02.25236.25236.4 0.0012 15/180 K.AVTPPMPLLTPATPGGLPPAAAVAAAAATAK[136.11].L "sp|Q9UHX1|PUF60_HUMAN,tr|A0A0J9YYL3|A0A0J9YYL3_HUMAN,tr|A0A0J9YWM1|A0A0J9YWM1_HUMAN,tr|H0YEM1|H0YEM1_HUMAN,tr|A0A0J9YVR6|A0A0J9YVR6_HUMAN,tr|A0A0J9YXX5|A0A0J9YXX5_HUMAN,tr|A0A0J9YXJ8|A0A0J9YXJ8_HUMAN,tr|E9PQ56|E9PQ56_HUMAN,tr|H0YCP8|H0YCP8_HUMAN,tr|A0A0J9YVP6|A0A0J9YVP6_HUMAN" 10 2801.5605 -1 23796 25236 4 2801.561907 701.3974 Poly(U)-binding-splicing factor PUF60 OS=Homo sapiens OX=9606 GN=PUF60 PE=1 SV=1 8.8 3995 - 1.55E+06 - - - 0.5119 - 2.874 0.38 - 64.2 1 2 0 0.0014 31 0 0 0 0.00E+00 0.00E+00 - - - 2.854 0.9999 221125_WJC_METTL3_EV_vs_WT_F02.25238.25238.3 4.76E-08 15/64 R.SLLK[136.11]EEDPAVLISEVLR[166.11].R "sp|Q9H019|MFR1L_HUMAN,tr|E9PLD2|E9PLD2_HUMAN" 2 1928.0949 2.66 23798 25238 3 1928.09294 643.7056 Mitochondrial fission regulator 1-like OS=Homo sapiens OX=9606 GN=MTFR1L PE=1 SV=2 4.41 3995.2 - 1.29E+06 - - - -1.0238 - 3.166 0.581 - 294.4 1 2 1 -0.002 17 0 0 0 7.52E+06 2.83E+06 - - - 7.9285 1 221125_WJC_METTL3_EV_vs_WT_F02.25240.25240.3 1.38E-16 29/84 R.KPLVIIAEDVDGEALSTLVLNR.L "sp|P10809|CH60_HUMAN,tr|A0A7I2V2X6|A0A7I2V2X6_HUMAN,tr|A0A7I2YQK6|A0A7I2YQK6_HUMAN,tr|A0A7I2V599|A0A7I2V599_HUMAN,tr|A0A7I2YQ71|A0A7I2YQ71_HUMAN,tr|A0A7I2V5M1|A0A7I2V5M1_HUMAN,tr|A0A7I2V5K3|A0A7I2V5K3_HUMAN" 7 2364.3264 1.19 23799 25240 3 2364.327063 789.1161 "60 kDa heat shock protein, mitochondrial OS=Homo sapiens OX=9606 GN=HSPD1 PE=1 SV=2" 4.32 3995.4 - 1.57E+07 - - - 0.269 - 5.348 0.646 - 1069.2 1 2 0 0.0006 22 0 0 0 1.07E+08 8.98E+07 - - - 9.7173 1 221125_WJC_METTL3_EV_vs_WT_F02.25243.25243.3 1.66E-12 17/64 K.ATENDIYNFFSPLNPVR.V "sp|P52597|HNRPF_HUMAN,sp|P31943|HNRH1_HUMAN,tr|H0YBD7|H0YBD7_HUMAN,tr|H0YB39|H0YB39_HUMAN,tr|H0YBG7|H0YBG7_HUMAN,tr|E9PCY7|E9PCY7_HUMAN,tr|G8JLB6|G8JLB6_HUMAN" 7 1995.969 1.25 23802 25243 3 1995.970704 666.3303 Heterogeneous nuclear ribonucleoprotein F OS=Homo sapiens OX=9606 GN=HNRNPF PE=1 SV=3 4.37 3995.6 - 1.63E+07 - - - 0.8332 - 3.334 0.677 - 297.1 1 2 0 0.0017 17 0 0 0 2.26E+08 1.81E+08 - - - 9.1295 1 221125_WJC_METTL3_EV_vs_WT_F02.25244.25244.3 4.67E-06 18/64 K.ATENDIYNFFSPLNPVR[166.11].V "sp|P52597|HNRPF_HUMAN,sp|P31943|HNRH1_HUMAN,tr|H0YBD7|H0YBD7_HUMAN,tr|H0YB39|H0YB39_HUMAN,tr|H0YBG7|H0YBG7_HUMAN,tr|E9PCY7|E9PCY7_HUMAN,tr|G8JLB6|G8JLB6_HUMAN" 7 2005.9773 1.25 23803 25244 3 2005.976337 669.6664 Heterogeneous nuclear ribonucleoprotein F OS=Homo sapiens OX=9606 GN=HNRNPF PE=1 SV=3 4.37 3995.6 - 1.51E+07 - - - -0.4855 - 3.263 0.614 - 323.1 1 2 0 -0.001 17 0 0 0 2.26E+08 1.81E+08 - - - 8.3729 1 221125_WJC_METTL3_EV_vs_WT_F02.25245.25245.2 2.26E-15 21/32 K.ATENDIYNFFSPLNPVR.V "sp|P52597|HNRPF_HUMAN,sp|P31943|HNRH1_HUMAN,tr|H0YBD7|H0YBD7_HUMAN,tr|H0YB39|H0YB39_HUMAN,tr|H0YBG7|H0YBG7_HUMAN,tr|E9PCY7|E9PCY7_HUMAN,tr|G8JLB6|G8JLB6_HUMAN" 7 1995.969 1.17 23804 25245 2 1995.9703 998.9918 Heterogeneous nuclear ribonucleoprotein F OS=Homo sapiens OX=9606 GN=HNRNPF PE=1 SV=3 4.37 3995.7 - 7.96E+06 - - - 0.6308 - 3.427 0.715 - 1256.4 1 2 0 0.0013 17 0 0 0 1.28E+08 1.09E+08 - - - 7.3497 1 221125_WJC_METTL3_EV_vs_WT_F02.25249.25249.3 4.89E-06 21/56 R.QVLLSAAEAAEVILR[166.11].V sp|P78371|TCPB_HUMAN 1 1591.9173 -1 23808 25249 3 1591.917101 531.6464 T-complex protein 1 subunit beta OS=Homo sapiens OX=9606 GN=CCT2 PE=1 SV=4 4.53 3996 - 1.82E+06 - - - -0.1106 - 3.609 0.551 - 833.6 1 2 0 -0.0002 15 0 0 0 0.00E+00 0.00E+00 - - - 8.032 1 221125_WJC_METTL3_EV_vs_WT_F02.25250.25250.2 1.16E-09 21/38 R.LIDVPDPVPALDLGQQLQLK.V "sp|Q13948|CASP_HUMAN,sp|P39880|CUX1_HUMAN,tr|A0A2R8Y852|A0A2R8Y852_HUMAN,tr|A0A2R8YDI1|A0A2R8YDI1_HUMAN" 4 2171.2202 -1 23809 25250 2 2171.221226 1086.6174 Protein CASP OS=Homo sapiens OX=9606 GN=CUX1 PE=1 SV=2 3.93 3996.1 - 1.81E+06 - - - 0.4859 - 2.862 0.695 - 858.3 1 2 0 0.0011 20 0 0 0 0.00E+00 0.00E+00 - - - 6.7592 0.9999 221125_WJC_METTL3_EV_vs_WT_F02.25251.25251.3 6.86E-06 13/64 R.DVMQQQLAEYQELLDVK.L sp|Q03252|LMNB2_HUMAN 1 2049.0089 -1 23810 25251 3 2049.003236 684.0102 Lamin-B2 OS=Homo sapiens OX=9606 GN=LMNB2 PE=1 SV=4 3.92 3996.2 - 1.77E+06 - - - -2.7433 - 2.41 0.497 - 170 1 2 0 -0.0056 17 0 0 0 0.00E+00 0.00E+00 - - - 6.3017 1 221125_WJC_METTL3_EV_vs_WT_F02.25254.25254.2 8.64E-11 23/42 R.KPLVIIAEDVDGEALSTLVLNR.L "sp|P10809|CH60_HUMAN,tr|A0A7I2V2X6|A0A7I2V2X6_HUMAN,tr|A0A7I2YQK6|A0A7I2YQK6_HUMAN,tr|A0A7I2V599|A0A7I2V599_HUMAN,tr|A0A7I2YQ71|A0A7I2YQ71_HUMAN,tr|A0A7I2V5M1|A0A7I2V5M1_HUMAN,tr|A0A7I2V5K3|A0A7I2V5K3_HUMAN" 7 2364.3264 1.22 23813 25254 2 2364.328226 1183.1705 "60 kDa heat shock protein, mitochondrial OS=Homo sapiens OX=9606 GN=HSPD1 PE=1 SV=2" 4.32 3996.5 - 721731 - - - 0.7609 - 4.6 0.711 - 1489.4 1 2 0 0.0018 22 0 0 0 4.72E+06 3.85E+06 - - - 8.0438 0.9994 221125_WJC_METTL3_EV_vs_WT_F02.25261.25261.3 3.54E-05 20/68 K.TSTVDLPIENQLLWQIDR[166.11].E sp|P34932|HSP74_HUMAN 1 2150.1247 0.26 23818 25261 3 2150.117368 717.7155 Heat shock 70 kDa protein 4 OS=Homo sapiens OX=9606 GN=HSPA4 PE=1 SV=4 4.03 3997.4 - 6.94E+06 - - - -3.4119 - 3.596 0.302 - 473.3 1 2 0 -0.0073 18 0 0 0 7.84E+06 3.00E+07 - - - 5.0919 1 221125_WJC_METTL3_EV_vs_WT_F02.25262.25262.2 4.97E-13 19/32 K.ATENDIYNFFSPLNPVR[166.11].V "sp|P52597|HNRPF_HUMAN,sp|P31943|HNRH1_HUMAN,tr|H0YBD7|H0YBD7_HUMAN,tr|H0YB39|H0YB39_HUMAN,tr|H0YBG7|H0YBG7_HUMAN,tr|E9PCY7|E9PCY7_HUMAN,tr|G8JLB6|G8JLB6_HUMAN" 7 2005.9773 1.17 23819 25262 2 2005.977028 1003.9959 Heterogeneous nuclear ribonucleoprotein F OS=Homo sapiens OX=9606 GN=HNRNPF PE=1 SV=3 4.37 3997.4 - 2.70E+07 - - - -0.1411 - 3.384 0.71 - 1130.5 1 2 0 -0.0003 17 0 0 0 1.28E+08 1.09E+08 - - - 7.2821 0.9999 221125_WJC_METTL3_EV_vs_WT_F02.25263.25263.2 2.28E-05 22-Nov R.SLDLDSIIDAVR.T sp|Q7Z794|K2C1B_HUMAN 1 1315.6983 -1 23820 25263 2 1315.698371 658.8564 "Keratin, type II cytoskeletal 1b OS=Homo sapiens OX=9606 GN=KRT77 PE=1 SV=3" 3.93 3997.5 - 7.11E+06 - - - 0.019 - 2.383 0.52 - 374.8 1 2 0 0 12 0 0 0 0.00E+00 0.00E+00 - - - 5.1665 1 221125_WJC_METTL3_EV_vs_WT_F02.25264.25264.3 0.000297 18/68 R.ILAIGLINEALDEGDAQK.T "sp|P46940|IQGA1_HUMAN,tr|A0A0J9YXZ5|A0A0J9YXZ5_HUMAN" 2 1882.0048 2.3 23821 25264 3 1882.002285 628.3422 Ras GTPase-activating-like protein IQGAP1 OS=Homo sapiens OX=9606 GN=IQGAP1 PE=1 SV=1 3.92 3997.5 - 3.86E+06 - - - -1.314 - 3.64 0.629 - 574.3 1 2 0 -0.0025 18 0 0 0 2.18E+07 9.47E+06 - - - 8.7692 1 221125_WJC_METTL3_EV_vs_WT_F02.25265.25265.3 5.37E-12 17/64 R.ATENDIANFFSPLNPIR.V sp|P31942|HNRH3_HUMAN 1 1917.9585 2.48 23822 25265 3 1917.959658 640.3268 Heterogeneous nuclear ribonucleoprotein H3 OS=Homo sapiens OX=9606 GN=HNRNPH3 PE=1 SV=2 4.37 3997.6 - 3.35E+06 - - - 0.6158 - 3.226 0.666 - 378.6 1 2 0 0.0012 17 0 0 0 3.67E+07 1.48E+07 - - - 8.9238 1 221125_WJC_METTL3_EV_vs_WT_F02.25267.25267.3 2.17E-12 21/80 K.TEDPDLPAFYFDPLINPISHR.H "sp|Q6P2Q9|PRP8_HUMAN,tr|I3L0J9|I3L0J9_HUMAN" 2 2456.2012 -1 23824 25267 3 2456.197381 819.741 Pre-mRNA-processing-splicing factor 8 OS=Homo sapiens OX=9606 GN=PRPF8 PE=1 SV=2 4.22 3997.7 - 2.28E+06 - - - -1.5654 - 3.705 0.684 - 427.2 1 2 0 -0.0038 21 0 0 0 0.00E+00 0.00E+00 - - - 9.3048 1 221125_WJC_METTL3_EV_vs_WT_F02.25268.25268.2 1.62E-11 21/32 R.ATENDIANFFSPLNPIR.V sp|P31942|HNRH3_HUMAN 1 1917.9585 -1 23825 25268 2 1917.9566 959.9865 Heterogeneous nuclear ribonucleoprotein H3 OS=Homo sapiens OX=9606 GN=HNRNPH3 PE=1 SV=2 4.37 3997.8 - 1.96E+06 - - - -0.9786 - 3.631 0.677 - 1497.8 1 2 0 -0.0019 17 0 0 0 0.00E+00 0.00E+00 - - - 7.211 1 221125_WJC_METTL3_EV_vs_WT_F02.25269.25269.3 1.46E-11 23/64 R.ATENDIANFFSPLNPIR[166.11].V sp|P31942|HNRH3_HUMAN 1 1927.9667 -1 23826 25269 3 1927.967319 643.6629 Heterogeneous nuclear ribonucleoprotein H3 OS=Homo sapiens OX=9606 GN=HNRNPH3 PE=1 SV=2 4.37 3997.9 - 1.62E+06 - - - 0.2967 - 3.859 0.638 - 644 1 2 0 0.0006 17 0 0 0 0.00E+00 0.00E+00 - - - 9.0644 1 221125_WJC_METTL3_EV_vs_WT_F02.25270.25270.2 4.94E-05 17/34 R.ILAIGLINEALDEGDAQK[136.11].T "sp|P46940|IQGA1_HUMAN,tr|A0A0J9YXZ5|A0A0J9YXZ5_HUMAN" 2 1890.019 -1 23827 25270 2 1890.01867 946.0168 Ras GTPase-activating-like protein IQGAP1 OS=Homo sapiens OX=9606 GN=IQGAP1 PE=1 SV=1 3.92 3998 - 1.52E+06 - - - -0.1524 - 3.674 0.548 - 777.4 1 2 0 -0.0003 18 0 0 0 0.00E+00 0.00E+00 - - - 6.2877 1 221125_WJC_METTL3_EV_vs_WT_F02.25271.25271.2 4.70E-10 19/34 R.ILAIGLINEALDEGDAQK.T "sp|P46940|IQGA1_HUMAN,tr|A0A0J9YXZ5|A0A0J9YXZ5_HUMAN" 2 1882.0048 -1 23828 25271 2 1882.005499 942.0097 Ras GTPase-activating-like protein IQGAP1 OS=Homo sapiens OX=9606 GN=IQGAP1 PE=1 SV=1 3.92 3998.2 - 1.51E+06 - - - 0.3937 - 3.941 0.543 - 1205.2 1 2 0 0.0007 18 0 0 0 0.00E+00 0.00E+00 - - - 6.4231 1 221125_WJC_METTL3_EV_vs_WT_F02.25273.25273.2 2.19E-10 15/30 R.GQPFEVLIIASDDGFK.A sp|P47929|LEG7_HUMAN 1 1734.8829 -1 23830 25273 2 1734.885922 868.4487 Galectin-7 OS=Homo sapiens OX=9606 GN=LGALS7 PE=1 SV=2 4.03 3998.4 - 1.18E+06 - - - 1.7696 - 2.936 0.631 - 602.1 1 2 0 0.0031 16 0 0 0 0.00E+00 0.00E+00 - - - 6.3486 0.9997 221125_WJC_METTL3_EV_vs_WT_F02.25275.25275.3 8.94E-07 17/88 R.SQPLYLPPGPAPPSALLSGLALK[136.11].G sp|P48634|PRC2A_HUMAN 1 2294.313 2.05 23832 25275 3 2294.318749 765.7783 Protein PRRC2A OS=Homo sapiens OX=9606 GN=PRRC2A PE=1 SV=3 8.31 3998.6 - 1.02E+06 - - - 2.5254 - 2.723 0.389 - 232.4 1 2 0 0.0058 23 0 0 0 9.00E+06 4.38E+06 - - - 5.2254 0.9991 221125_WJC_METTL3_EV_vs_WT_F02.25276.25276.2 0.00274 28-Aug K.QSQLQELILQQIAFK.N "sp|Q14186|TFDP1_HUMAN,tr|Q5JSB5|Q5JSB5_HUMAN" 2 1785.9989 -1 23833 25276 2 1786.001334 894.0067 Transcription factor Dp-1 OS=Homo sapiens OX=9606 GN=TFDP1 PE=1 SV=1 6 3998.8 - 904166 - - - 1.3712 - 1.506 0.388 - 92.1 1 2 0 0.0024 15 0 0 0 0.00E+00 0.00E+00 - - - 2.9127 0.9998 221125_WJC_METTL3_EV_vs_WT_F02.25278.25278.2 8.54E-05 Aug-32 K.TGLSSEQTVNVLAQILK[136.11].R "sp|P35269|T2FA_HUMAN,tr|M0QXD6|M0QXD6_HUMAN" 2 1808.0135 -1 23835 25278 2 1808.014748 905.014 General transcription factor IIF subunit 1 OS=Homo sapiens OX=9606 GN=GTF2F1 PE=1 SV=2 5.66 3999 - 580167 - - - 0.7019 - 2.138 0.441 - 172.8 1 2 0 0.0013 17 0 0 0 0.00E+00 0.00E+00 - - - 4.166 1 221125_WJC_METTL3_EV_vs_WT_F02.25286.25286.3 1.42E-08 15/68 K.SMEAEMIQLQEELAAAER.A sp|P35579|MYH9_HUMAN 1 2047.9554 -1 23842 25286 3 2047.959716 683.6591 Myosin-9 OS=Homo sapiens OX=9606 GN=MYH9 PE=1 SV=4 3.98 3999.7 - 5.45E+06 - - - 2.0874 - 3.217 0.655 - 370 1 2 0 0.0043 18 0 0 0 0.00E+00 0.00E+00 - - - 8.751 1 221125_WJC_METTL3_EV_vs_WT_F02.25288.25288.2 1.17E-12 18/32 R.ATENDIANFFSPLNPIR[166.11].V sp|P31942|HNRH3_HUMAN 1 1927.9667 -1 23844 25288 2 1927.964972 964.9906 Heterogeneous nuclear ribonucleoprotein H3 OS=Homo sapiens OX=9606 GN=HNRNPH3 PE=1 SV=2 4.37 3999.9 - 4.05E+06 - - - -0.9207 - 3.382 0.675 - 1078.4 1 2 0 -0.0018 17 0 0 0 0.00E+00 0.00E+00 - - - 7.0217 0.9977 221125_WJC_METTL3_EV_vs_WT_F02.25290.25290.3 1.45E-05 16/48 K.NILQELLGQPVQR.P sp|Q9NRA8|4ET_HUMAN 1 1506.8518 -1 23846 25290 3 1506.853363 503.2912 Eukaryotic translation initiation factor 4E transporter OS=Homo sapiens OX=9606 GN=EIF4ENIF1 PE=1 SV=2 6 4000 - 3.33E+06 - - - 1.0193 - 2.989 0.502 - 404.3 1 1 0 0.0015 13 0 0 0 0.00E+00 0.00E+00 - - - 7.1051 0.9865 221125_WJC_METTL3_EV_vs_WT_F02.25292.25292.3 0.00328 15/48 K.NILQELLGQPVQR[166.11].P sp|Q9NRA8|4ET_HUMAN 1 1516.8601 -1 23848 25292 3 1516.860737 506.6273 Eukaryotic translation initiation factor 4E transporter OS=Homo sapiens OX=9606 GN=EIF4ENIF1 PE=1 SV=2 6 4000.1 - 3.03E+06 - - - 0.4219 - 2.634 0.339 - 338.4 1 1 0 0.0006 13 0 0 0 0.00E+00 0.00E+00 - - - 4.9452 1 221125_WJC_METTL3_EV_vs_WT_F02.25294.25294.3 5.72E-06 23/72 K.EIVDPLYGIAEVEIPNIQK.Q "sp|Q68EM7|RHG17_HUMAN,tr|C9IZD3|C9IZD3_HUMAN,tr|I3L4P6|I3L4P6_HUMAN" 3 2139.1463 -1 23850 25294 3 2139.148597 714.0561 Rho GTPase-activating protein 17 OS=Homo sapiens OX=9606 GN=ARHGAP17 PE=1 SV=1 4 4000.3 - 1.86E+06 - - - 1.0565 - 3.895 0.562 - 461.1 1 2 0 0.0023 19 0 0 0 0.00E+00 0.00E+00 - - - 8.1456 1 221125_WJC_METTL3_EV_vs_WT_F02.25296.25296.2 6.09E-12 17/32 R.WFGFLEAQQAFQSVGTK[136.11].W "sp|P07814|SYEP_HUMAN,tr|V9GZ76|V9GZ76_HUMAN,tr|V9GYZ6|V9GYZ6_HUMAN" 3 1950.9719 0.38 23852 25296 2 1950.969641 976.4933 Bifunctional glutamate\proline--tRNA ligase OS=Homo sapiens OX=9606 GN=EPRS1 PE=1 SV=5 6 4000.6 - 1.52E+06 - - - -1.1825 - 3.332 0.65 - 1144.8 1 2 0 -0.0023 17 0 0 0 2.73E+06 7.29E+06 - - - 6.8002 0.9997 221125_WJC_METTL3_EV_vs_WT_F02.25297.25297.3 0.00784 Oct-64 R.WFGFLEAQQAFQSVGTK.W "sp|P07814|SYEP_HUMAN,tr|V9GZ76|V9GZ76_HUMAN,tr|V9GYZ6|V9GYZ6_HUMAN" 3 1942.9577 1.1 23853 25297 3 1942.959988 648.6599 Bifunctional glutamate\proline--tRNA ligase OS=Homo sapiens OX=9606 GN=EPRS1 PE=1 SV=5 6 4000.6 - 1.47E+06 - - - 1.1529 - 2.1 0.354 - 167.6 1 2 0 0.0022 17 0 0 0 3.45E+06 3.14E+06 - - - 4.3605 1 221125_WJC_METTL3_EV_vs_WT_F02.25303.25303.2 1.27E-14 19/42 R.K[136.11]PLVIIAEDVDGEALSTLVLNR[166.11].L "sp|P10809|CH60_HUMAN,tr|A0A7I2V2X6|A0A7I2V2X6_HUMAN,tr|A0A7I2YQK6|A0A7I2YQK6_HUMAN,tr|A0A7I2V599|A0A7I2V599_HUMAN,tr|A0A7I2YQ71|A0A7I2YQ71_HUMAN,tr|A0A7I2V5M1|A0A7I2V5M1_HUMAN,tr|A0A7I2V5K3|A0A7I2V5K3_HUMAN" 7 2382.3489 1.22 23858 25303 2 2382.350297 1192.1817 "60 kDa heat shock protein, mitochondrial OS=Homo sapiens OX=9606 GN=HSPD1 PE=1 SV=2" 4.32 4001.3 - 229182 - - - 0.5877 - 3.511 0.753 - 753.2 1 2 0 0.0014 22 0 0 0 4.72E+06 3.85E+06 - - - 7.6899 1 221125_WJC_METTL3_EV_vs_WT_F02.25304.25304.3 2.95E-18 23/104 K.EIAEAYLGYPVTNAVITVPAYFNDSQR[166.11].Q "sp|P0DMV8|HS71A_HUMAN,sp|P0DMV9|HS71B_HUMAN,tr|A0A0G2JIW1|A0A0G2JIW1_HUMAN" 3 3010.4952 -1 23859 25304 3 3010.494421 1004.5057 Heat shock 70 kDa protein 1A OS=Homo sapiens OX=9606 GN=HSPA1A PE=1 SV=1 4.14 4001.4 - 3.39E+07 - - - -0.2498 - 5.2 0.706 - 292.5 1 2 0 -0.0008 27 0 0 0 0.00E+00 0.00E+00 - - - 10.204 1 221125_WJC_METTL3_EV_vs_WT_F02.25305.25305.3 1.18E-13 30/88 K.SINPDEAVAYGAAVQAAILSGDK.S "sp|P11142|HSP7C_HUMAN,tr|E9PNE6|E9PNE6_HUMAN,tr|A8K7Q2|A8K7Q2_HUMAN,tr|E9PKE3|E9PKE3_HUMAN" 4 2259.1383 -1 23860 25305 3 2259.13907 754.0534 Heat shock cognate 71 kDa protein OS=Homo sapiens OX=9606 GN=HSPA8 PE=1 SV=1 4.03 4001.4 - 2.61E+07 - - - 0.3444 - 4.405 0.684 - 959.9 1 2 0 0.0008 23 0 0 0 0.00E+00 0.00E+00 - - - 9.6441 1 221125_WJC_METTL3_EV_vs_WT_F02.25307.25307.3 2.65E-15 27/104 K.EIAEAYLGYPVTNAVITVPAYFNDSQR.Q "sp|P0DMV8|HS71A_HUMAN,sp|P0DMV9|HS71B_HUMAN,tr|A0A0G2JIW1|A0A0G2JIW1_HUMAN" 3 3000.4869 0.15 23862 25307 3 3000.488883 1001.1696 Heat shock 70 kDa protein 1A OS=Homo sapiens OX=9606 GN=HSPA1A PE=1 SV=1 4.14 4001.6 - 5.20E+06 - - - 0.6599 - 4.881 0.709 - 302.4 1 2 0 0.002 27 0 0 0 1.43E+07 9.54E+07 - - - 10.0914 1 221125_WJC_METTL3_EV_vs_WT_F02.25308.25308.2 1.43E-11 22/44 K.SINPDEAVAYGAAVQAAILSGDK.S "sp|P11142|HSP7C_HUMAN,tr|E9PNE6|E9PNE6_HUMAN,tr|A8K7Q2|A8K7Q2_HUMAN,tr|E9PKE3|E9PKE3_HUMAN" 4 2259.1383 -1 23863 25308 2 2259.13948 1130.5764 Heat shock cognate 71 kDa protein OS=Homo sapiens OX=9606 GN=HSPA8 PE=1 SV=1 4.03 4001.7 - 4.36E+06 - - - 0.5259 - 4.29 0.713 - 1353.6 1 2 0 0.0012 23 0 0 0 0.00E+00 0.00E+00 - - - 7.8872 0.9999 221125_WJC_METTL3_EV_vs_WT_F02.25309.25309.2 0.000518 22-Dec R.SLDLDSIIAEVK.A sp|P04264|K2C1_HUMAN 1 1301.7078 999 23864 25309 2 1301.707995 651.8612 "Keratin, type II cytoskeletal 1 OS=Homo sapiens OX=9606 GN=KRT1 PE=1 SV=6" 4.03 4001.7 - 3.22E+06 - - - 0.1129 - 2.649 0.451 - 312.7 1 2 0 0.0001 12 0 0 0 8.44E+06 0.00E+00 - - - 4.9353 1 221125_WJC_METTL3_EV_vs_WT_F02.25311.25311.3 2.10E-12 25/80 R.FDGALNVDLTEFQTNLVPYPR[166.11].L "sp|Q9NY65|TBA8_HUMAN,sp|Q6PEY2|TBA3E_HUMAN,sp|P0DPH7|TBA3C_HUMAN,sp|Q71U36|TBA1A_HUMAN,sp|P0DPH8|TBA3D_HUMAN,sp|P68366|TBA4A_HUMAN,sp|P68363|TBA1B_HUMAN,sp|Q9BQE3|TBA1C_HUMAN,tr|F8VVB9|F8VVB9_HUMAN,tr|C9JDS9|C9JDS9_HUMAN,tr|A0A7P0TA31|A0A7P0TA31_HUMAN,tr|F5H5D3|F5H5D3_HUMAN,tr|C9J2C0|C9J2C0_HUMAN,tr|V9GZ17|V9GZ17_HUMAN,tr|A0A7P0T945|A0A7P0T945_HUMAN" 15 2418.2095 -1 23866 25311 3 2418.203699 807.0771 Tubulin alpha-8 chain OS=Homo sapiens OX=9606 GN=TUBA8 PE=1 SV=1 4.03 4001.9 - 2.51E+06 - - - -2.3972 - 4.525 0.642 - 486.9 1 2 0 -0.0058 21 0 0 0 0.00E+00 0.00E+00 - - - 9.3153 1 221125_WJC_METTL3_EV_vs_WT_F02.25312.25312.2 9.15E-06 18/28 K.LTFLYLANDVIQNSK.R "sp|Q96P16|RPR1A_HUMAN,sp|Q9NQG5|RPR1B_HUMAN,tr|E9PIQ9|E9PIQ9_HUMAN,tr|A0A0C4DGQ6|A0A0C4DGQ6_HUMAN" 4 1737.9301 -1 23867 25312 2 1737.931418 869.9723 Regulation of nuclear pre-mRNA domain-containing protein 1A OS=Homo sapiens OX=9606 GN=RPRD1A PE=1 SV=1 5.83 4002 - 2.07E+06 - - - 0.7371 - 3.463 0.6 - 1083.6 1 2 0 0.0013 15 0 0 0 0.00E+00 0.00E+00 - - - 6.526 1 221125_WJC_METTL3_EV_vs_WT_F02.25313.25313.2 4.10E-20 24/52 K.EIAEAYLGYPVTNAVITVPAYFNDSQR[166.11].Q "sp|P0DMV8|HS71A_HUMAN,sp|P0DMV9|HS71B_HUMAN,tr|A0A0G2JIW1|A0A0G2JIW1_HUMAN" 3 3010.4952 -1 23868 25313 2 3010.495238 1506.2549 Heat shock 70 kDa protein 1A OS=Homo sapiens OX=9606 GN=HSPA1A PE=1 SV=1 4.14 4002.1 - 2.00E+06 - - - 0.0216 - 5.496 0.765 - 825.7 1 2 0 0.0001 27 0 0 0 0.00E+00 0.00E+00 - - - 8.8807 1 221125_WJC_METTL3_EV_vs_WT_F02.25314.25314.3 1.28E-07 28/80 K.LVQIEYALAAVAGGAPSVGIK[136.11].A "sp|P25787|PSA2_HUMAN,tr|H3BT36|H3BT36_HUMAN,tr|A0A024RA52|A0A024RA52_HUMAN,tr|A0A7I2V2H3|A0A7I2V2H3_HUMAN" 4 2034.1605 -1 23869 25314 3 2034.162984 679.0608 Proteasome subunit alpha type-2 OS=Homo sapiens OX=9606 GN=PSMA2 PE=1 SV=2 6 4002.2 - 1.79E+06 - - - 1.2324 - 4.798 0.514 - 1081.8 1 2 0 0.0025 21 0 0 0 0.00E+00 0.00E+00 - - - 8.0296 1 221125_WJC_METTL3_EV_vs_WT_F02.25317.25317.3 4.40E-08 14/68 K.VVLDVGSGTGILC[160.03]MFAAK.A "sp|Q99873|ANM1_HUMAN,tr|E9PQ98|E9PQ98_HUMAN,tr|E9PKG1|E9PKG1_HUMAN,tr|E9PNR9|E9PNR9_HUMAN,tr|H0YDE4|H0YDE4_HUMAN,tr|E9PMW9|E9PMW9_HUMAN,tr|E9PIX6|E9PIX6_HUMAN" 7 1836.9478 -1 23872 25317 3 1836.951027 613.3232 Protein arginine N-methyltransferase 1 OS=Homo sapiens OX=9606 GN=PRMT1 PE=1 SV=3 5.8 4002.5 - 1.21E+06 - - - 1.7687 - 2.712 0.506 - 242.8 1 2 0 0.0032 18 0 0 0 0.00E+00 0.00E+00 - - - 6.6648 0.9998 221125_WJC_METTL3_EV_vs_WT_F02.25323.25323.2 6.67E-05 15/36 K.EIVDPLYGIAEVEIPNIQK[136.11].Q "sp|Q68EM7|RHG17_HUMAN,tr|C9IZD3|C9IZD3_HUMAN,tr|I3L4P6|I3L4P6_HUMAN" 3 2147.1605 -1 23877 25323 2 2147.160319 1074.5875 Rho GTPase-activating protein 17 OS=Homo sapiens OX=9606 GN=ARHGAP17 PE=1 SV=1 4 4003.2 - 567241 - - - -0.1015 - 2.031 0.446 - 381 1 2 0 -0.0002 19 0 0 0 0.00E+00 0.00E+00 - - - 4.077 1 221125_WJC_METTL3_EV_vs_WT_F02.25325.25325.3 3.63E-09 27/84 R.TLTAVHDAILEDLVFPSEIVGK.R "sp|P62081|RS7_HUMAN,tr|B5MCP9|B5MCP9_HUMAN,tr|A0A2R8Y623|A0A2R8Y623_HUMAN" 3 2366.2733 0.96 23879 25325 3 2366.273065 789.7651 40S ribosomal protein S7 OS=Homo sapiens OX=9606 GN=RPS7 PE=1 SV=1 4.31 4003.4 - 1.73E+07 - - - -0.1116 - 4.345 0.68 - 929.5 1 2 0 -0.0003 22 0 0 0 1.65E+08 1.71E+08 - - - 9.6041 1 221125_WJC_METTL3_EV_vs_WT_F02.25328.25328.2 2.66E-11 16/26 K.VEWSAFLEAADNLR.L sp|Q9UI30|TR112_HUMAN 1 1619.7944 -1 23882 25328 2 1619.792596 810.9045 Multifunctional methyltransferase subunit TRM112-like protein OS=Homo sapiens OX=9606 GN=TRMT112 PE=1 SV=1 4.14 4003.5 - 5.44E+06 - - - -1.0958 - 3.022 0.664 - 1016.5 1 2 0 -0.0018 14 0 0 0 0.00E+00 0.00E+00 - - - 6.72 1 221125_WJC_METTL3_EV_vs_WT_F02.25331.25331.3 2.94E-07 Dec-52 K.VEWSAFLEAADNLR.L sp|Q9UI30|TR112_HUMAN 1 1619.7944 -1 23885 25331 3 1619.793232 540.9387 Multifunctional methyltransferase subunit TRM112-like protein OS=Homo sapiens OX=9606 GN=TRMT112 PE=1 SV=1 4.14 4003.8 - 2.31E+06 - - - -0.7032 - 2.779 0.609 - 265.7 1 2 0 -0.0011 14 0 0 0 0.00E+00 0.00E+00 - - - 8.0457 0.9999 221125_WJC_METTL3_EV_vs_WT_F02.25334.25334.3 0.00027 Sep-52 K.VEWSAFLEAADNLR[166.11].L sp|Q9UI30|TR112_HUMAN 1 1629.8026 0.31 23888 25334 3 1629.803381 544.2748 Multifunctional methyltransferase subunit TRM112-like protein OS=Homo sapiens OX=9606 GN=TRMT112 PE=1 SV=1 4.14 4004 - 2.07E+06 - - - 0.454 - 2.038 0.434 - 114.7 1 2 0 0.0007 14 0 0 0 3.62E+06 1.16E+07 - - - 5.2705 1 221125_WJC_METTL3_EV_vs_WT_F02.25336.25336.2 8.83E-08 16/28 R.QNLEPLFEQYINNLR.R "sp|P48668|K2C6C_HUMAN,sp|P04259|K2C6B_HUMAN,sp|P13647|K2C5_HUMAN,sp|P02538|K2C6A_HUMAN,tr|F8W0C6|F8W0C6_HUMAN" 5 1889.9636 -1 23890 25336 2 1889.963216 945.9891 "Keratin, type II cytoskeletal 6C OS=Homo sapiens OX=9606 GN=KRT6C PE=1 SV=3" 4.53 4004.3 - 1.27E+06 - - - -0.1831 - 3.346 0.61 - 718.4 1 2 0 -0.0003 15 0 0 0 0.00E+00 0.00E+00 - - - 6.5157 0.9999 221125_WJC_METTL3_EV_vs_WT_F02.25342.25342.4 9.33E-09 15/102 R.ADLEMQIESLKEELAYLK.K sp|P02533|K1C14_HUMAN 1 2122.0868 -1 23896 25342 4 2122.084719 531.529 "Keratin, type I cytoskeletal 14 OS=Homo sapiens OX=9606 GN=KRT14 PE=1 SV=4" 4.25 4005 - 512344 - - - -0.9679 - 3.208 0.537 - 127.7 1 2 1 -0.0021 18 0 0 0 0.00E+00 0.00E+00 - - - 4.2988 1 221125_WJC_METTL3_EV_vs_WT_F02.25344.25344.3 7.06E-10 17/68 R.ADLEMQIESLKEELAYLK.K sp|P02533|K1C14_HUMAN 1 2122.0868 999 23897 25344 3 2122.087758 708.3695 "Keratin, type I cytoskeletal 14 OS=Homo sapiens OX=9606 GN=KRT14 PE=1 SV=4" 4.25 4005.2 - 4.08E+07 - - - 0.4642 - 4.193 0.657 - 437.5 1 2 1 0.001 18 0 0 0 1.45E+08 0.00E+00 - - - 9.434 1 221125_WJC_METTL3_EV_vs_WT_F02.25346.25346.3 3.48E-05 18/48 R.DALSDLALHFLNK[136.11].M sp|P50991|TCPD_HUMAN 1 1463.7864 -1 23899 25346 3 1463.78503 488.9361 T-complex protein 1 subunit delta OS=Homo sapiens OX=9606 GN=CCT4 PE=1 SV=4 5.21 4005.4 - 2.36E+07 - - - -0.9216 - 3.405 0.439 - 442.9 1 2 0 -0.0013 13 0 0 0 0.00E+00 0.00E+00 - - - 6.756 1 221125_WJC_METTL3_EV_vs_WT_F02.25349.25349.3 1.48E-09 16/56 R.QNLEPLFEQYINNLR.R "sp|P48668|K2C6C_HUMAN,sp|P04259|K2C6B_HUMAN,sp|P13647|K2C5_HUMAN,sp|P02538|K2C6A_HUMAN,tr|F8W0C6|F8W0C6_HUMAN" 5 1889.9636 92.03 23902 25349 3 1889.963447 630.9951 "Keratin, type II cytoskeletal 6C OS=Homo sapiens OX=9606 GN=KRT6C PE=1 SV=3" 4.53 4005.6 - 8.77E+06 - - - -0.0608 - 3.199 0.601 - 436.7 1 2 0 -0.0001 15 0 0 0 1.97E+08 2.14E+06 - - - 8.2748 1 221125_WJC_METTL3_EV_vs_WT_F02.25350.25350.3 0.0281 19/48 R.DALSDLALHFLNK.M sp|P50991|TCPD_HUMAN 1 1455.7722 0.45 23903 25350 3 1455.77126 486.2647 T-complex protein 1 subunit delta OS=Homo sapiens OX=9606 GN=CCT4 PE=1 SV=4 5.21 4005.6 - 8.74E+06 - - - -0.6313 - 3.345 0.463 - 514.4 1 2 0 -0.0009 13 0 0 0 2.76E+07 6.15E+07 - - - 6.9755 1 221125_WJC_METTL3_EV_vs_WT_F02.25352.25352.3 1.11E-07 22/80 K.LFVGGLSFDTNEQSLEQVFSK.Y "sp|Q14011|CIRBP_HUMAN,tr|K7ER40|K7ER40_HUMAN,tr|K7EQL0|K7EQL0_HUMAN,tr|K7ENX8|K7ENX8_HUMAN,tr|K7EJV1|K7EJV1_HUMAN,tr|K7EJV5|K7EJV5_HUMAN,tr|K7ELT6|K7ELT6_HUMAN,tr|K7EIF7|K7EIF7_HUMAN,tr|K7EMY9|K7EMY9_HUMAN,tr|K7EQX4|K7EQX4_HUMAN,tr|K7ELV6|K7ELV6_HUMAN,tr|K7EQR7|K7EQR7_HUMAN,tr|K7EPM4|K7EPM4_HUMAN,tr|K7ENN6|K7ENN6_HUMAN,tr|D6W5Y5|D6W5Y5_HUMAN" 15 2344.1587 -1 23905 25352 3 2344.159314 782.3935 Cold-inducible RNA-binding protein OS=Homo sapiens OX=9606 GN=CIRBP PE=1 SV=1 4.14 4005.7 - 6.37E+06 - - - 0.2649 - 3.787 0.624 - 452.5 1 2 0 0.0006 21 0 0 0 0.00E+00 0.00E+00 - - - 8.6892 1 221125_WJC_METTL3_EV_vs_WT_F02.25353.25353.3 9.58E-08 16/88 K.SINPDEAVAYGAAVQAAILSGDK[136.11].S "sp|P11142|HSP7C_HUMAN,tr|E9PNE6|E9PNE6_HUMAN,tr|A8K7Q2|A8K7Q2_HUMAN,tr|E9PKE3|E9PKE3_HUMAN" 4 2267.1525 0.19 23906 25353 3 2267.148455 756.7248 Heat shock cognate 71 kDa protein OS=Homo sapiens OX=9606 GN=HSPA8 PE=1 SV=1 4.03 4005.7 - 5.39E+06 - - - -1.7806 - 2.83 0.517 - 250.6 1 2 0 -0.004 23 0 0 0 5.59E+07 3.02E+08 - - - 6.7434 1 221125_WJC_METTL3_EV_vs_WT_F02.25354.25354.3 4.70E-12 29/64 R.PINLEPIFQGYIDSLKR.Y sp|P35908|K22E_HUMAN 1 2002.0888 999 23907 25354 3 2002.089756 668.3702 "Keratin, type II cytoskeletal 2 epidermal OS=Homo sapiens OX=9606 GN=KRT2 PE=1 SV=2" 6.49 4005.8 - 5.03E+06 - - - 0.496 - 4.414 0.653 - 1298.2 1 1 0 0.001 17 0 0 0 2.46E+07 0.00E+00 - - - 9.571 1 221125_WJC_METTL3_EV_vs_WT_F02.25356.25356.2 1.68E-13 27/42 R.TLTAVHDAILEDLVFPSEIVGK.R "sp|P62081|RS7_HUMAN,tr|B5MCP9|B5MCP9_HUMAN,tr|A0A2R8Y623|A0A2R8Y623_HUMAN" 3 2366.2733 -1 23909 25356 2 2366.274981 1184.1439 40S ribosomal protein S7 OS=Homo sapiens OX=9606 GN=RPS7 PE=1 SV=1 4.31 4006 - 3.40E+06 - - - 0.6981 - 5.171 0.763 - 2000.1 1 2 0 0.0017 22 0 0 0 0.00E+00 0.00E+00 - - - 8.7156 1 221125_WJC_METTL3_EV_vs_WT_F02.25357.25357.2 8.96E-16 25/40 K.LFVGGLSFDTNEQSLEQVFSK[136.11].Y "sp|Q14011|CIRBP_HUMAN,tr|K7ER40|K7ER40_HUMAN,tr|K7EQL0|K7EQL0_HUMAN,tr|K7ENX8|K7ENX8_HUMAN,tr|K7EJV1|K7EJV1_HUMAN,tr|K7EJV5|K7EJV5_HUMAN,tr|K7ELT6|K7ELT6_HUMAN,tr|K7EIF7|K7EIF7_HUMAN,tr|K7EMY9|K7EMY9_HUMAN,tr|K7EQX4|K7EQX4_HUMAN,tr|K7ELV6|K7ELV6_HUMAN,tr|K7EQR7|K7EQR7_HUMAN,tr|K7EPM4|K7EPM4_HUMAN,tr|K7ENN6|K7ENN6_HUMAN,tr|D6W5Y5|D6W5Y5_HUMAN" 15 2352.1729 -1 23910 25357 2 2352.170615 1177.0937 Cold-inducible RNA-binding protein OS=Homo sapiens OX=9606 GN=CIRBP PE=1 SV=1 4.14 4006.1 - 1.84E+06 - - - -0.9685 - 4.389 0.696 - 1782.4 1 2 0 -0.0023 21 0 0 0 0.00E+00 0.00E+00 - - - 7.8174 0.9999 221125_WJC_METTL3_EV_vs_WT_F02.25358.25358.3 0.000819 13/48 R.FDLLWLIQDR[166.11]PDR[166.11].D sp|P33993|MCM7_HUMAN 1 1705.9055 -1 23911 25358 3 1705.905444 569.6424 DNA replication licensing factor MCM7 OS=Homo sapiens OX=9606 GN=MCM7 PE=1 SV=4 4.43 4006.2 - 1.44E+06 - - - -0.0211 - 2.532 0.433 - 241.3 1 2 0 0 13 0 0 0 0.00E+00 0.00E+00 - - - 5.8863 1 221125_WJC_METTL3_EV_vs_WT_F02.25361.25361.2 6.39E-09 15/44 K.SINPDEAVAYGAAVQAAILSGDK[136.11].S "sp|P11142|HSP7C_HUMAN,tr|E9PNE6|E9PNE6_HUMAN,tr|A8K7Q2|A8K7Q2_HUMAN,tr|E9PKE3|E9PKE3_HUMAN" 4 2267.1525 0.16 23914 25361 2 2267.148121 1134.5835 Heat shock cognate 71 kDa protein OS=Homo sapiens OX=9606 GN=HSPA8 PE=1 SV=1 4.03 4006.6 - 1.16E+06 - - - -1.928 - 2.9 0.594 - 252.3 1 2 0 -0.0044 23 0 0 0 1.25E+07 7.71E+07 - - - 6.0446 0.9974 221125_WJC_METTL3_EV_vs_WT_F02.25391.25391.3 1.53E-07 17/60 R.NVQALEIELQSQLALK.Q "sp|P13645|K1C10_HUMAN,tr|A0A1B0GVI3|A0A1B0GVI3_HUMAN" 2 1796.0044 -1 23931 25391 3 1796.019303 599.6754 "Keratin, type I cytoskeletal 10 OS=Homo sapiens OX=9606 GN=KRT10 PE=1 SV=6" 4.53 4008.7 - 1.44E+06 - - - 8.3179 - 2.536 0.512 - 134.8 1 2 0 0.0149 16 0 0 0 0.00E+00 0.00E+00 - - - 6.6319 0.899 221125_WJC_METTL3_EV_vs_WT_F02.25398.25398.2 0.0171 30-Jul R.NVQALEIELQSQLALK.Q "sp|P13645|K1C10_HUMAN,tr|A0A1B0GVI3|A0A1B0GVI3_HUMAN" 2 1796.0044 -1 23938 25398 2 1796.014774 899.0095 "Keratin, type I cytoskeletal 10 OS=Homo sapiens OX=9606 GN=KRT10 PE=1 SV=6" 4.53 4009.5 - 1.08E+06 - - - 5.7962 - 0.783 0.403 - 57.5 1 2 0 0.0104 16 0 0 0 0.00E+00 0.00E+00 - - - 1.4129 1 221125_WJC_METTL3_EV_vs_WT_F02.26081.26081.3 5.44E-15 25/84 R.KPLVIIAEDVDGEALSTLVLNR.L "sp|P10809|CH60_HUMAN,tr|A0A7I2V2X6|A0A7I2V2X6_HUMAN,tr|A0A7I2YQK6|A0A7I2YQK6_HUMAN,tr|A0A7I2V599|A0A7I2V599_HUMAN,tr|A0A7I2YQ71|A0A7I2YQ71_HUMAN,tr|A0A7I2V5M1|A0A7I2V5M1_HUMAN,tr|A0A7I2V5K3|A0A7I2V5K3_HUMAN" 7 2364.3264 -1 24013 26081 3 2364.328364 789.1161 "60 kDa heat shock protein, mitochondrial OS=Homo sapiens OX=9606 GN=HSPD1 PE=1 SV=2" 4.32 4137 - 2.57E+07 - - - 0.8193 - 4.756 0.635 - 792.2 1 2 0 0.0019 22 0 0 0 0.00E+00 0.00E+00 - - - 9.3162 1 221125_WJC_METTL3_EV_vs_WT_F02.26082.26082.3 2.10E-06 23/84 R.K[136.11]PLVIIAEDVDGEALSTLVLNR[166.11].L "sp|P10809|CH60_HUMAN,tr|A0A7I2V2X6|A0A7I2V2X6_HUMAN,tr|A0A7I2YQK6|A0A7I2YQK6_HUMAN,tr|A0A7I2V599|A0A7I2V599_HUMAN,tr|A0A7I2YQ71|A0A7I2YQ71_HUMAN,tr|A0A7I2V5M1|A0A7I2V5M1_HUMAN,tr|A0A7I2V5K3|A0A7I2V5K3_HUMAN" 7 2382.3489 -1 24014 26082 3 2382.348507 795.1236 "60 kDa heat shock protein, mitochondrial OS=Homo sapiens OX=9606 GN=HSPD1 PE=1 SV=2" 4.32 4137 - 1.94E+07 - - - -0.1637 - 4.895 0.701 - 666.2 1 2 0 -0.0004 22 0 0 0 0.00E+00 0.00E+00 - - - 10.1207 0.9999 221125_WJC_METTL3_EV_vs_WT_F02.26084.26084.4 0.00278 4/126 R.KPLVIIAEDVDGEALSTLVLNR.L "sp|P10809|CH60_HUMAN,tr|A0A7I2V2X6|A0A7I2V2X6_HUMAN,tr|A0A7I2YQK6|A0A7I2YQK6_HUMAN,tr|A0A7I2V599|A0A7I2V599_HUMAN,tr|A0A7I2YQ71|A0A7I2YQ71_HUMAN,tr|A0A7I2V5M1|A0A7I2V5M1_HUMAN,tr|A0A7I2V5K3|A0A7I2V5K3_HUMAN" 7 2364.3264 -1 24015 26084 4 2364.329396 592.0889 "60 kDa heat shock protein, mitochondrial OS=Homo sapiens OX=9606 GN=HSPD1 PE=1 SV=2" 4.32 4137.2 - 4.63E+06 - - - 1.2557 - 0.951 0.454 - 5 1 2 0 0.003 22 0 0 0 0.00E+00 0.00E+00 - - - 3.1604 0.9969 221125_WJC_METTL3_EV_vs_WT_F03.03188.03188.2 0.00749 12-Jul R.MVQEAEK[136.11].Y "sp|P0DMV8|HS71A_HUMAN,sp|P11142|HSP7C_HUMAN,sp|P0DMV9|HS71B_HUMAN,tr|E9PNE6|E9PNE6_HUMAN,tr|A8K7Q2|A8K7Q2_HUMAN,tr|E9PKE3|E9PKE3_HUMAN,tr|E9PM13|E9PM13_HUMAN,tr|E9PS65|E9PS65_HUMAN,tr|V9GZ37|V9GZ37_HUMAN,tr|A0A0G2JIW1|A0A0G2JIW1_HUMAN" 10 841.4095 0.13 24115 3188 2 841.406849 421.712 Heat shock 70 kDa protein 1A OS=Homo sapiens OX=9606 GN=HSPA1A PE=1 SV=1 4.53 1338.6 - 551619 - - - -3.1554 - 1.493 0.339 - 182.4 1 2 0 -0.0027 7 0 0 0 2.43E+06 1.90E+07 - - - 2.8139 0.9973 221125_WJC_METTL3_EV_vs_WT_F03.03243.03243.2 0.186 12-Aug K.HPELADK[136.11].N "sp|Q9NQ39|RS10L_HUMAN,sp|P46783|RS10_HUMAN,tr|A0A2R8Y6L3|A0A2R8Y6L3_HUMAN,tr|F6U211|F6U211_HUMAN,tr|A0A1W2PQS6|A0A1W2PQS6_HUMAN,tr|A0A2R8YFH6|A0A2R8YFH6_HUMAN,tr|A0A2R8Y7H1|A0A2R8Y7H1_HUMAN,tr|S4R435|S4R435_HUMAN" 8 816.4221 5.11 24117 3243 2 816.421873 409.2183 Putative 40S ribosomal protein S10-like OS=Homo sapiens OX=9606 GN=RPS10P5 PE=5 SV=1 5.32 1348.3 - 592397 - - - -0.3001 - 1.134 0.287 - 181.7 1 2 0 -0.0002 7 0 0 0 1.09E+08 2.14E+07 - - - 1.5592 0.9955 221125_WJC_METTL3_EV_vs_WT_F03.03558.03558.2 0.211 12-Aug K.LEDAEAR[166.11].E sp|L0R8F8|MIDUO_HUMAN 1 812.3904 1.24 24142 3558 2 812.388939 407.2025 MIEF1 upstream open reading frame protein OS=Homo sapiens OX=9606 GN=MIEF1 PE=1 SV=1 4.14 1401.3 - 796340 - - - -1.7578 - 1.657 0.133 - 224.3 1 2 0 -0.0014 7 0 0 0 1.83E+08 1.47E+08 - - - 1.623 0.9892 221125_WJC_METTL3_EV_vs_WT_F03.03565.03565.2 0.185 12-Aug K.LEDAEAR.E sp|L0R8F8|MIDUO_HUMAN 1 802.3821 1.24 24144 3565 2 802.381211 402.1983 MIEF1 upstream open reading frame protein OS=Homo sapiens OX=9606 GN=MIEF1 PE=1 SV=1 4.14 1402.3 - 2.19E+06 - - - -1.1042 - 1.486 0.057 - 235.4 1 2 0 -0.0009 7 0 0 0 1.83E+08 1.47E+08 - - - 0.7168 0.9929 221125_WJC_METTL3_EV_vs_WT_F03.03630.03630.2 0.0342 12-Jul K.AVANTMR.T "sp|P48643|TCPE_HUMAN,tr|E9PCA1|E9PCA1_HUMAN,tr|B7ZAR1|B7ZAR1_HUMAN,tr|E7ENZ3|E7ENZ3_HUMAN,tr|H0Y914|H0Y914_HUMAN" 5 761.3854 0.6 24148 3630 2 761.383035 381.7 T-complex protein 1 subunit epsilon OS=Homo sapiens OX=9606 GN=CCT5 PE=1 SV=1 9.79 1413.2 - 8.67E+06 - - - -3.1167 - 1.304 0.293 - 169.5 1 2 0 -0.0024 7 0 0 0 8.85E+08 1.48E+09 - - - 2.0454 0.9931 221125_WJC_METTL3_EV_vs_WT_F03.03681.03681.2 0.392 12-Jul K.VLTGEEK[136.11].A "sp|Q96ST2|IWS1_HUMAN,tr|A0A1B0GW95|A0A1B0GW95_HUMAN" 2 782.4265 1.15 24152 3681 2 782.426679 392.2205 Protein IWS1 homolog OS=Homo sapiens OX=9606 GN=IWS1 PE=1 SV=2 4.53 1421.5 - 741114 - - - 0.1853 - 1.466 0.086 - 173.6 1 2 0 0.0001 7 0 0 0 5.08E+07 4.41E+07 - - - 0.8882 0.9859 221125_WJC_METTL3_EV_vs_WT_F03.03758.03758.2 0.413 12-Jun R.ITPEEAK.Y sp|P62701|RS4X_HUMAN 1 786.4123 1.08 24156 3758 2 786.410855 394.2134 "40S ribosomal protein S4, X isoform OS=Homo sapiens OX=9606 GN=RPS4X PE=1 SV=2" 4.53 1434.7 - 911678 - - - -1.8807 - 1.302 0.132 - 127.1 1 2 0 -0.0015 7 0 0 0 1.24E+09 1.15E+09 - - - 0.8517 0.9947 221125_WJC_METTL3_EV_vs_WT_F03.03769.03769.2 0.504 12-Jul R.ITPEEAK[136.11].Y sp|P62701|RS4X_HUMAN 1 794.4265 1.09 24158 3769 2 794.425071 398.2205 "40S ribosomal protein S4, X isoform OS=Homo sapiens OX=9606 GN=RPS4X PE=1 SV=2" 4.53 1436.4 - 3.47E+06 - - - -1.8416 - 1.467 0.175 - 228.9 1 2 0 -0.0015 7 0 0 0 1.25E+09 1.15E+09 - - - 1.5473 0.8249 221125_WJC_METTL3_EV_vs_WT_F03.03901.03901.2 0.2 12-Aug K.PVAVEEK[136.11].V "sp|Q8WUD4|CCD12_HUMAN,tr|C9JUN5|C9JUN5_HUMAN,tr|J3KR35|J3KR35_HUMAN" 3 778.4316 76.37 24171 3901 2 778.429515 390.2231 Coiled-coil domain-containing protein 12 OS=Homo sapiens OX=9606 GN=CCDC12 PE=1 SV=1 4.53 1458.3 - 610854 - - - -2.7042 - 1.58 0.257 - 238.6 1 1 0 -0.0021 7 0 0 0 3.70E+09 4.85E+07 - - - 2.3879 0.9895 221125_WJC_METTL3_EV_vs_WT_F03.03929.03929.2 2.52 12-Jun R.NSTIPTK[136.11].Q "sp|P0DMV8|HS71A_HUMAN,sp|P34931|HS71L_HUMAN,sp|P0DMV9|HS71B_HUMAN,tr|Q53FA3|Q53FA3_HUMAN,tr|V9GZ37|V9GZ37_HUMAN,tr|A0A0G2JIW1|A0A0G2JIW1_HUMAN" 6 767.4269 0.28 24177 3929 2 767.42597 384.7207 Heat shock 70 kDa protein 1A OS=Homo sapiens OX=9606 GN=HSPA1A PE=1 SV=1 8.75 1462.8 - 4.42E+06 - - - -1.1714 - 1.243 0.14 - 163.5 1 2 0 -0.0009 7 0 0 0 4.15E+07 1.48E+08 - - - 0.764 0.9992 221125_WJC_METTL3_EV_vs_WT_F03.04025.04025.2 0.008 18-Nov R.IAGQVAAANK.K "sp|P39019|RS19_HUMAN,tr|A0A075B6E2|A0A075B6E2_HUMAN" 2 941.5294 1.21 24187 4025 2 941.528 471.772 40S ribosomal protein S19 OS=Homo sapiens OX=9606 GN=RPS19 PE=1 SV=2 8.75 1478.5 - 1.01E+06 - - - -1.5188 - 1.849 0.299 - 305.6 1 2 0 -0.0014 10 0 0 0 2.74E+07 2.28E+07 - - - 2.9646 0.9985 221125_WJC_METTL3_EV_vs_WT_F03.04050.04050.2 0.0257 12-Jul R.MGQTMER.L "sp|P52272|HNRPM_HUMAN,tr|A0A087X0X3|A0A087X0X3_HUMAN,tr|M0QZM1|M0QZM1_HUMAN" 3 851.363 1.58 24191 4050 2 851.360999 426.6888 Heterogeneous nuclear ribonucleoprotein M OS=Homo sapiens OX=9606 GN=HNRNPM PE=1 SV=3 5.75 1482.5 - 907016 - - - -2.301 - 1.239 0.434 - 136.5 1 2 0 -0.002 7 0 0 0 4.76E+07 3.01E+07 - - - 2.9249 0.98 221125_WJC_METTL3_EV_vs_WT_F03.04068.04068.2 0.384 12-Jun R.ALDDTAR.E "sp|P20700|LMNB1_HUMAN,tr|A0A0D9SFY5|A0A0D9SFY5_HUMAN,tr|E9PBF6|E9PBF6_HUMAN,tr|A0A0D9SFE5|A0A0D9SFE5_HUMAN" 4 760.3715 0.87 24194 4068 2 760.369257 381.193 Lamin-B1 OS=Homo sapiens OX=9606 GN=LMNB1 PE=1 SV=2 4.21 1485.3 - 1.06E+06 - - - -2.992 - 1.216 0.204 - 136.3 1 2 0 -0.0023 7 0 0 0 8.91E+07 1.03E+08 - - - 1.1667 0.8859 221125_WJC_METTL3_EV_vs_WT_F03.04080.04080.2 1.93 12-May -.MSSAIER[166.11].K sp|P25791|RBTN2_HUMAN 1 802.3883 1.51 24195 4080 2 802.385839 402.2014 Rhombotin-2 OS=Homo sapiens OX=9606 GN=LMO2 PE=1 SV=1 5.75 1487.2 - 3.69E+06 - - - -3.0147 - 0.941 0.191 - 63 5 2 0 -0.0024 7 0 0 0 2.85E+08 1.88E+08 - - - -0.054 0.9654 221125_WJC_METTL3_EV_vs_WT_F03.04090.04090.2 7.03 12-Jul R.R[166.11]YYEEER[166.11].K "sp|Q9UPQ0|LIMC1_HUMAN,tr|E9PDJ9|E9PDJ9_HUMAN,tr|G5EA03|G5EA03_HUMAN,tr|E7EPK0|E7EPK0_HUMAN,tr|H0Y8P3|H0Y8P3_HUMAN,tr|D6RD46|D6RD46_HUMAN" 6 1063.4838 0.001 24198 4090 2 1063.483766 532.7492 LIM and calponin homology domains-containing protein 1 OS=Homo sapiens OX=9606 GN=LIMCH1 PE=1 SV=4 4.79 1488.6 - 470337 - - - 0.0028 - 1.188 0.029 - 82.8 1 2 0 0 7 0 0 0 0.00E+00 1.63E+07 - - - -0.199 0.9704 221125_WJC_METTL3_EV_vs_WT_F03.04117.04117.2 0.887 14-Aug M.AVVATAER.G "sp|P78406|RAE1L_HUMAN,tr|E9PQ57|E9PQ57_HUMAN,tr|E9PPG9|E9PPG9_HUMAN" 3 815.4501 1.56 24202 4117 2 815.449517 408.7323 mRNA export factor OS=Homo sapiens OX=9606 GN=RAE1 PE=1 SV=1 6.05 1492.9 - 814653 - - - -0.7358 - 1.67 0.339 - 289.8 1 1 0 -0.0006 8 0 0 0 9.90E+07 6.33E+07 - - - 3.0913 0.9987 221125_WJC_METTL3_EV_vs_WT_F03.04136.04136.2 0.0243 12-Jul K.VVANAYK.T sp|Q5VT52|RPRD2_HUMAN 1 763.4228 1.39 24208 4136 2 763.422273 382.7187 Regulation of nuclear pre-mRNA domain-containing protein 2 OS=Homo sapiens OX=9606 GN=RPRD2 PE=1 SV=1 8.56 1495.6 - 2.17E+06 - - - -0.7414 - 1.285 0.325 - 141.9 1 2 0 -0.0006 7 0 0 0 8.19E+07 5.91E+07 - - - 2.2358 0.9618 221125_WJC_METTL3_EV_vs_WT_F03.04144.04144.2 0.225 12-Jun R.VLSTEER[166.11].K sp|O75717|WDHD1_HUMAN 1 842.4373 0.35 24210 4144 2 842.434504 422.2259 WD repeat and HMG-box DNA-binding protein 1 OS=Homo sapiens OX=9606 GN=WDHD1 PE=1 SV=1 4.53 1496.8 - 1.28E+06 - - - -3.3391 - 1.236 0.158 - 157.5 1 2 0 -0.0028 7 0 0 0 2.69E+07 7.76E+07 - - - 0.8785 0.9972 221125_WJC_METTL3_EV_vs_WT_F03.04146.04146.2 0.00219 12-Aug K.VVANAYK[136.11].T sp|Q5VT52|RPRD2_HUMAN 1 771.437 1.39 24212 4146 2 771.434666 386.7258 Regulation of nuclear pre-mRNA domain-containing protein 2 OS=Homo sapiens OX=9606 GN=RPRD2 PE=1 SV=1 8.56 1496.9 - 2.84E+06 - - - -3.0761 - 1.449 0.358 - 200.3 1 2 0 -0.0024 7 0 0 0 8.19E+07 5.91E+07 - - - 2.8596 0.8949 221125_WJC_METTL3_EV_vs_WT_F03.04170.04170.2 5.29 12-May K.YLASGDR.S sp|O43818|U3IP2_HUMAN 1 780.3766 0.52 24217 4170 2 780.375117 391.1956 U3 small nucleolar RNA-interacting protein 2 OS=Homo sapiens OX=9606 GN=RRP9 PE=1 SV=1 5.84 1500.7 - 1.61E+06 - - - -1.9221 - 1.05 0.079 - 93.4 4 2 0 -0.0015 7 0 0 0 7.60E+07 1.47E+08 - - - -0.4903 0.9841 221125_WJC_METTL3_EV_vs_WT_F03.04177.04177.2 0.438 12-Jul K.LAESVEK[136.11].A sp|Q9Y5B9|SP16H_HUMAN 1 782.4265 0.32 24219 4177 2 782.425225 392.2205 FACT complex subunit SPT16 OS=Homo sapiens OX=9606 GN=SUPT16H PE=1 SV=1 4.53 1501.7 - 2.24E+06 - - - -1.673 - 1.348 0.111 - 141.5 2 2 0 -0.0013 7 0 0 0 2.75E+08 8.61E+08 - - - 0.6722 0.9987 221125_WJC_METTL3_EV_vs_WT_F03.04178.04178.2 0.21 12-Jun K.YLASGDR[166.11].S sp|O43818|U3IP2_HUMAN 1 790.3849 0.39 24220 4178 2 790.384387 396.1997 U3 small nucleolar RNA-interacting protein 2 OS=Homo sapiens OX=9606 GN=RRP9 PE=1 SV=1 5.84 1501.8 - 1.22E+06 - - - -0.6326 - 1.249 0.33 - 130.4 1 2 0 -0.0005 7 0 0 0 5.39E+07 1.37E+08 - - - 2.1827 0.8844 221125_WJC_METTL3_EV_vs_WT_F03.04194.04194.2 2.6 16-Jul K.LVGGTTPGK[136.11].G "sp|P53597|SUCA_HUMAN,tr|A0A494C0D1|A0A494C0D1_HUMAN" 2 836.4847 2.53 24224 4194 2 836.485493 419.2496 "Succinate--CoA ligase [ADP\GDP-forming] subunit alpha, mitochondrial OS=Homo sapiens OX=9606 GN=SUCLG1 PE=1 SV=4" 8.75 1504.2 - 426598 - - - 0.9265 - 0.947 0.055 - 110.3 2 2 0 0.0008 9 0 0 0 1.77E+07 6.99E+06 - - - -0.845 0.963 221125_WJC_METTL3_EV_vs_WT_F03.04218.04218.2 0.4 12-Jun K.EVATDVR[166.11].L "sp|O75534|CSDE1_HUMAN,tr|E9PLT0|E9PLT0_HUMAN,tr|E9PNG3|E9PNG3_HUMAN" 3 798.4111 1.6 24227 4218 2 798.408406 400.2128 Cold shock domain-containing protein E1 OS=Homo sapiens OX=9606 GN=CSDE1 PE=1 SV=2 4.37 1508.1 - 3.21E+06 - - - -3.3767 - 1.303 0.141 - 201.1 1 2 0 -0.0027 7 0 0 0 2.04E+09 1.27E+09 - - - 0.9202 0.9959 221125_WJC_METTL3_EV_vs_WT_F03.04225.04225.2 0.0165 12-Jun R.LVEDEER[166.11].R "sp|Q14204|DYHC1_HUMAN,tr|A0A7P0T8N2|A0A7P0T8N2_HUMAN,tr|A0A7P0T9C4|A0A7P0T9C4_HUMAN,tr|A0A7P0TBJ7|A0A7P0TBJ7_HUMAN,tr|A0A804HHY6|A0A804HHY6_HUMAN,tr|A0A7P0T9K2|A0A7P0T9K2_HUMAN,tr|A0A7P0TB64|A0A7P0TB64_HUMAN,tr|A0A2R8Y706|A0A2R8Y706_HUMAN,tr|A0A7P0T916|A0A7P0T916_HUMAN,tr|A0A7P0TB75|A0A7P0TB75_HUMAN,tr|A0A7P0T8W5|A0A7P0T8W5_HUMAN,tr|A0A7P0TAF3|A0A7P0TAF3_HUMAN,tr|A0A7P0T9F1|A0A7P0T9F1_HUMAN,tr|A0A7P0TAW9|A0A7P0TAW9_HUMAN,tr|A0A7P0TA13|A0A7P0TA13_HUMAN,tr|A0A7P0TAV5|A0A7P0TAV5_HUMAN,tr|A0A7P0T7V5|A0A7P0T7V5_HUMAN,tr|A0A7P0T9R4|A0A7P0T9R4_HUMAN,tr|A0A2R8Y5T0|A0A2R8Y5T0_HUMAN,tr|A0A7P0T990|A0A7P0T990_HUMAN,tr|A0A2R8YFZ7|A0A2R8YFZ7_HUMAN,tr|A0A7P0T825|A0A7P0T825_HUMAN,tr|A0A2R8Y6H2|A0A2R8Y6H2_HUMAN,tr|A0A7P0TAM4|A0A7P0TAM4_HUMAN" 24 898.4271 0.45 24230 4225 2 898.424385 450.2208 Cytoplasmic dynein 1 heavy chain 1 OS=Homo sapiens OX=9606 GN=DYNC1H1 PE=1 SV=5 4 1509 - 486638 - - - -3.0731 - 1.211 0.384 - 164 1 2 0 -0.0028 7 0 0 0 1.52E+07 3.39E+07 - - - 2.483 0.999 221125_WJC_METTL3_EV_vs_WT_F03.04236.04236.2 0.107 12-Aug R.VGSEIER.M "sp|P52272|HNRPM_HUMAN,tr|A0A087X0X3|A0A087X0X3_HUMAN,tr|M0QZM1|M0QZM1_HUMAN" 3 788.4028 1.6 24232 4236 2 788.401227 395.2087 Heterogeneous nuclear ribonucleoprotein M OS=Homo sapiens OX=9606 GN=HNRNPM PE=1 SV=3 4.53 1510.6 - 1.28E+07 - - - -2.0358 - 1.717 0.315 - 198.9 1 2 0 -0.0016 7 0 0 0 2.04E+09 1.27E+09 - - - 3.0799 0.8158 221125_WJC_METTL3_EV_vs_WT_F03.04255.04255.2 1.74 12-Sep R.PSSEVIK[136.11].D "sp|Q15717|ELAV1_HUMAN,tr|M0R055|M0R055_HUMAN,tr|M0QZR9|M0QZR9_HUMAN" 3 766.4316 0.81 24235 4255 2 766.429487 384.2231 ELAV-like protein 1 OS=Homo sapiens OX=9606 GN=ELAVL1 PE=1 SV=2 6.43 1513.6 - 7.65E+06 - - - -2.783 - 1.806 0.199 - 252.3 1 1 0 -0.0021 7 0 0 0 3.73E+08 4.63E+08 - - - 2.3831 0.8351 221125_WJC_METTL3_EV_vs_WT_F03.04256.04256.2 1.42 12-Sep R.PSSEVIK.D "sp|Q15717|ELAV1_HUMAN,tr|M0R055|M0R055_HUMAN,tr|M0QZR9|M0QZR9_HUMAN" 3 758.4174 0.81 24236 4256 2 758.415432 380.216 ELAV-like protein 1 OS=Homo sapiens OX=9606 GN=ELAVL1 PE=1 SV=2 6.43 1513.6 - 5.80E+06 - - - -2.6212 - 1.874 0.185 - 237.9 1 1 0 -0.002 7 0 0 0 3.73E+08 4.61E+08 - - - 2.3969 0.9812 221125_WJC_METTL3_EV_vs_WT_F03.04275.04275.2 0.588 14-Jul K.ILTGGADK[136.11].N sp|Q9UMS4|PRP19_HUMAN 1 781.4425 1.1 24241 4275 2 781.440092 391.7285 Pre-mRNA-processing factor 19 OS=Homo sapiens OX=9606 GN=PRPF19 PE=1 SV=1 5.84 1516.4 - 1.57E+07 - - - -3.1058 - 1.481 0.142 - 124.5 1 2 0 -0.0024 8 0 0 0 1.29E+09 1.18E+09 - - - 1.2735 0.908 221125_WJC_METTL3_EV_vs_WT_F03.04278.04278.2 1.06 12-Jun K.EQSIVEK[136.11].F "sp|Q86U44|MTA70_HUMAN,tr|H0YFV6|H0YFV6_HUMAN" 2 839.448 0.02 24242 4278 2 839.445659 420.7313 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 4.53 1516.8 - 558789 - - - -2.7864 - 1.304 0.015 - 243.2 1 2 0 -0.0023 7 0 0 0 3.20E+07 1.80E+09 - - - -0.0079 0.9986 221125_WJC_METTL3_EV_vs_WT_F03.04281.04281.2 0.013 16-Sep K.ILAEGGGAK.F sp|P49411|EFTU_HUMAN 1 814.4549 1.61 24243 4281 2 814.452075 408.2347 "Elongation factor Tu, mitochondrial OS=Homo sapiens OX=9606 GN=TUFM PE=1 SV=2" 6 1517.2 - 5.39E+06 - - - -3.4293 - 1.947 0.399 - 190.6 1 2 0 -0.0028 9 0 0 0 1.62E+09 1.01E+09 - - - 3.9147 0.9989 221125_WJC_METTL3_EV_vs_WT_F03.04288.04288.2 0.00372 16-Oct K.ILAEGGGAK[136.11].F sp|P49411|EFTU_HUMAN 1 822.4691 1.61 24245 4288 2 822.466224 412.2418 "Elongation factor Tu, mitochondrial OS=Homo sapiens OX=9606 GN=TUFM PE=1 SV=2" 6 1518.1 - 1.27E+07 - - - -3.4579 - 1.97 0.441 - 239.1 1 2 0 -0.0028 9 0 0 0 1.62E+09 1.01E+09 - - - 4.2589 0.8944 221125_WJC_METTL3_EV_vs_WT_F03.04329.04329.2 0.274 14-May K.KETSDGEK.E "sp|Q86W92|LIPB1_HUMAN,tr|F5GZP6|F5GZP6_HUMAN" 2 892.4138 27.83 24255 4329 2 892.418084 447.2142 Liprin-beta-1 OS=Homo sapiens OX=9606 GN=PPFIBP1 PE=1 SV=2 4.68 1524 - 4.31E+06 - - - 4.8105 - 1.406 0.14 - 64 3 2 0 0.0043 8 0 0 0 4.47E+08 1.61E+07 - - - 0.8882 0.9786 221125_WJC_METTL3_EV_vs_WT_F03.04331.04331.2 3.09 12-Jun R.LAQAGYR.A "sp|Q96IU4|ABHEB_HUMAN,sp|P34913|HYES_HUMAN,tr|E5RFU2|E5RFU2_HUMAN,tr|B4DQI4|B4DQI4_HUMAN,tr|F8W9U3|F8W9U3_HUMAN,tr|H0YAW7|H0YAW7_HUMAN,tr|E5RFH6|E5RFH6_HUMAN" 7 777.4133 0.97 24256 4331 2 777.411454 389.7139 Protein ABHD14B OS=Homo sapiens OX=9606 GN=ABHD14B PE=1 SV=1 8.75 1524.2 - 2.79E+06 - - - -2.4221 - 1.302 0.128 - 106.6 1 2 0 -0.0019 7 0 0 0 6.31E+07 6.52E+07 - - - 0.822 0.9955 221125_WJC_METTL3_EV_vs_WT_F03.04333.04333.2 0.0249 12-Aug R.MGSGIER[166.11].M "sp|P52272|HNRPM_HUMAN,tr|A0A087X0X3|A0A087X0X3_HUMAN,tr|M0QZM1|M0QZM1_HUMAN" 3 758.362 0.001 24257 4333 2 758.359448 380.1883 Heterogeneous nuclear ribonucleoprotein M OS=Homo sapiens OX=9606 GN=HNRNPM PE=1 SV=3 5.75 1524.5 - 3.07E+07 - - - -3.4218 - 1.442 0.331 - 225.9 1 2 0 -0.0026 7 0 0 0 0.00E+00 7.89E+08 - - - 2.6447 0.9968 221125_WJC_METTL3_EV_vs_WT_F03.04350.04350.2 0.449 12-Jul R.LEEVTGK.L sp|O94906|PRP6_HUMAN 1 774.4123 1.68 24259 4350 2 774.412572 388.2134 Pre-mRNA-processing factor 6 OS=Homo sapiens OX=9606 GN=PRPF6 PE=1 SV=1 4.53 1527.2 - 5.57E+06 - - - 0.3073 - 1.434 0.172 - 148.4 1 2 0 0.0002 7 0 0 0 1.74E+08 1.03E+08 - - - 1.4535 0.9946 221125_WJC_METTL3_EV_vs_WT_F03.04374.04374.2 2.15 12-Jun K.LEDSEVR[166.11].S "sp|Q8N163|CCAR2_HUMAN,tr|A0A087X2B6|A0A087X2B6_HUMAN,tr|H0YB24|H0YB24_HUMAN,tr|G3V119|G3V119_HUMAN" 4 856.4166 1.24 24265 4374 2 856.415286 429.2156 Cell cycle and apoptosis regulator protein 2 OS=Homo sapiens OX=9606 GN=CCAR2 PE=1 SV=2 4.14 1530.8 - 1.24E+06 - - - -1.5121 - 1.396 0.173 - 138.4 1 2 0 -0.0013 7 0 0 0 8.20E+07 6.62E+07 - - - 1.3754 0.9734 221125_WJC_METTL3_EV_vs_WT_F03.04379.04379.2 1.76 12-Jun K.LIEESQR.K sp|Q9H307|PININ_HUMAN 1 873.4556 2 24267 4379 2 873.45408 437.7351 Pinin OS=Homo sapiens OX=9606 GN=PNN PE=1 SV=5 4.53 1531.4 - 1.43E+06 - - - -1.7356 - 1.096 0.138 - 139.2 1 2 0 -0.0015 7 0 0 0 3.97E+07 1.98E+07 - - - 0.3502 0.9993 221125_WJC_METTL3_EV_vs_WT_F03.04381.04381.2 0.0561 14-Sep K.VAVATPAK[136.11].K "sp|P19338|NUCL_HUMAN,tr|A0A7I2V506|A0A7I2V506_HUMAN,tr|A0A7I2V699|A0A7I2V699_HUMAN,tr|A0A7I2V2U7|A0A7I2V2U7_HUMAN,tr|A0A7I2V3F3|A0A7I2V3F3_HUMAN,tr|A0A7I2V428|A0A7I2V428_HUMAN,tr|A0A7I2V349|A0A7I2V349_HUMAN,tr|H7BY16|H7BY16_HUMAN,tr|A0A7I2V5M5|A0A7I2V5M5_HUMAN,tr|A0A7I2V2S8|A0A7I2V2S8_HUMAN,tr|C9JLB1|C9JLB1_HUMAN" 11 763.4683 0.001 24268 4381 2 763.467507 382.7414 Nucleolin OS=Homo sapiens OX=9606 GN=NCL PE=1 SV=3 8.72 1531.7 - 4.09E+06 - - - -1.0898 - 1.45 0.376 - 254.5 1 2 0 -0.0008 8 0 0 0 0.00E+00 2.23E+08 - - - 2.9385 0.9643 221125_WJC_METTL3_EV_vs_WT_F03.04385.04385.2 0.711 12-May R.IYTDAGR.L "sp|P30876|RPB2_HUMAN,tr|C9J4M6|C9J4M6_HUMAN,tr|C9J2Y9|C9J2Y9_HUMAN" 3 794.3923 7.03 24270 4385 2 794.390176 398.2034 DNA-directed RNA polymerase II subunit RPB2 OS=Homo sapiens OX=9606 GN=POLR2B PE=1 SV=1 5.84 1532.1 - 1.26E+06 - - - -2.6322 - 1.197 0.159 - 74.7 3 2 0 -0.0021 7 0 0 0 4.10E+08 5.83E+07 - - - 0.5714 0.9513 221125_WJC_METTL3_EV_vs_WT_F03.04388.04388.2 4.16 12-Jun R.VTSIADR[166.11].L "sp|P60891|PRPS1_HUMAN,sp|P11908|PRPS2_HUMAN,tr|A0A2R8Y7H4|A0A2R8Y7H4_HUMAN,tr|B1ALA9|B1ALA9_HUMAN,tr|A0A6Q8PEU0|A0A6Q8PEU0_HUMAN,tr|A0A6Q8PG82|A0A6Q8PG82_HUMAN" 6 770.4162 0.91 24271 4388 2 770.414624 386.2154 Ribose-phosphate pyrophosphokinase 1 OS=Homo sapiens OX=9606 GN=PRPS1 PE=1 SV=2 5.81 1532.5 - 6.75E+06 - - - -2.0301 - 1.315 0.059 - 167.1 4 2 0 -0.0016 7 0 0 0 1.65E+08 1.81E+08 - - - 0.075 0.9814 221125_WJC_METTL3_EV_vs_WT_F03.04403.04403.2 0.546 12-Jun R.APQALER.Y sp|Q7Z5L9|I2BP2_HUMAN 1 783.4239 1.48 24273 4403 2 783.422296 392.7192 Interferon regulatory factor 2-binding protein 2 OS=Homo sapiens OX=9606 GN=IRF2BP2 PE=1 SV=2 6.05 1535 - 2.73E+06 - - - -2.05 - 1.299 0.136 - 123.4 2 2 0 -0.0016 7 0 0 0 3.97E+08 2.69E+08 - - - 0.7394 0.9962 221125_WJC_METTL3_EV_vs_WT_F03.04409.04409.2 0.22 12-Aug R.APQALER[166.11].Y sp|Q7Z5L9|I2BP2_HUMAN 1 793.4322 1.49 24275 4409 2 793.43034 397.7234 Interferon regulatory factor 2-binding protein 2 OS=Homo sapiens OX=9606 GN=IRF2BP2 PE=1 SV=2 6.05 1535.9 - 4.83E+06 - - - -2.309 - 1.482 0.242 - 273.9 1 2 0 -0.0018 7 0 0 0 3.92E+08 2.63E+08 - - - 2.0743 0.9979 221125_WJC_METTL3_EV_vs_WT_F03.04410.04410.2 0.336 14-Oct K.LITEGASK.R "sp|P50213|IDH3A_HUMAN,tr|H0YLI6|H0YLI6_HUMAN,tr|H0YL72|H0YL72_HUMAN,tr|H0YMU3|H0YMU3_HUMAN" 4 817.4545 1.51 24276 4410 2 817.453207 409.7345 "Isocitrate dehydrogenase [NAD] subunit alpha, mitochondrial OS=Homo sapiens OX=9606 GN=IDH3A PE=1 SV=1" 6 1536 - 1.91E+06 - - - -1.6221 - 1.673 0.216 - 239.5 1 2 0 -0.0013 8 0 0 0 1.98E+08 1.32E+08 - - - 2.188 0.9913 221125_WJC_METTL3_EV_vs_WT_F03.04411.04411.2 0.275 12-Jul K.VAIDNAR[166.11].A "sp|Q9UI36|DACH1_HUMAN,sp|Q96NX9|DACH2_HUMAN,tr|H0Y912|H0Y912_HUMAN,tr|A0A087WTT5|A0A087WTT5_HUMAN" 4 767.4165 0.24 24277 4411 2 767.414801 384.7155 Dachshund homolog 1 OS=Homo sapiens OX=9606 GN=DACH1 PE=1 SV=4 5.81 1536 - 3.39E+06 - - - -2.2426 - 1.396 0.174 - 183.3 1 2 0 -0.0017 7 0 0 0 3.04E+07 1.29E+08 - - - 1.3827 0.9908 221125_WJC_METTL3_EV_vs_WT_F03.04413.04413.2 0.848 12-Jun K.LYGK[136.11]PIR[166.11].V "sp|Q15427|SF3B4_HUMAN,tr|Q5SZ64|Q5SZ64_HUMAN" 2 863.5348 0.54 24279 4413 2 863.532738 432.7747 Splicing factor 3B subunit 4 OS=Homo sapiens OX=9606 GN=SF3B4 PE=1 SV=1 9.99 1536.3 - 809387 - - - -2.3798 - 1.253 0.225 - 140.8 1 2 0 -0.0021 7 0 0 0 1.67E+07 3.06E+07 - - - 1.4168 0.9764 221125_WJC_METTL3_EV_vs_WT_F03.04446.04446.2 0.0589 16-Aug K.VLENAEGAR[166.11].T "sp|P38646|GRP75_HUMAN,tr|H0Y8K0|H0Y8K0_HUMAN,tr|A0A7I2V2S7|A0A7I2V2S7_HUMAN,tr|A0A7I2V2G2|A0A7I2V2G2_HUMAN,tr|A0A3B3ITI4|A0A3B3ITI4_HUMAN,tr|A0A7I2V3F7|A0A7I2V3F7_HUMAN,tr|D6RCD7|D6RCD7_HUMAN" 7 967.4962 0.47 24287 4446 2 967.493879 484.7554 "Stress-70 protein, mitochondrial OS=Homo sapiens OX=9606 GN=HSPA9 PE=1 SV=2" 4.53 1540.9 - 3.08E+07 - - - -2.429 - 1.17 0.171 - 115 1 2 0 -0.0023 9 0 0 0 3.64E+08 7.76E+08 - - - 0.7575 0.9875 221125_WJC_METTL3_EV_vs_WT_F03.04449.04449.2 0.308 16-Aug K.VLENAEGAR.T "sp|P38646|GRP75_HUMAN,tr|H0Y8K0|H0Y8K0_HUMAN,tr|A0A7I2V2S7|A0A7I2V2S7_HUMAN,tr|A0A7I2V2G2|A0A7I2V2G2_HUMAN,tr|A0A3B3ITI4|A0A3B3ITI4_HUMAN,tr|A0A7I2V3F7|A0A7I2V3F7_HUMAN,tr|D6RCD7|D6RCD7_HUMAN" 7 957.488 0.47 24288 4449 2 957.484145 479.7513 "Stress-70 protein, mitochondrial OS=Homo sapiens OX=9606 GN=HSPA9 PE=1 SV=2" 4.53 1541.3 - 2.79E+06 - - - -3.9833 - 1.473 0.262 - 202.6 1 2 0 -0.0038 9 0 0 0 3.64E+08 7.76E+08 - - - 2.0954 0.809 221125_WJC_METTL3_EV_vs_WT_F03.04455.04455.2 2.88 12-Jun K.VIADNVK[136.11].D "sp|P60174|TPIS_HUMAN,tr|U3KQF3|U3KQF3_HUMAN,tr|U3KPZ0|U3KPZ0_HUMAN" 3 765.4476 0.12 24290 4455 2 765.444732 383.7311 Triosephosphate isomerase OS=Homo sapiens OX=9606 GN=TPI1 PE=1 SV=4 5.81 1542.1 - 8.85E+06 - - - -3.7521 - 1.249 0.022 - 115.5 1 2 0 -0.0029 7 0 0 0 3.11E+07 2.67E+08 - - - -0.0929 0.9867 221125_WJC_METTL3_EV_vs_WT_F03.04461.04461.2 0.0164 12-Jul K.YAEAVTR.A sp|P00558|PGK1_HUMAN 1 808.4079 1.21 24293 4461 2 808.404183 405.2112 Phosphoglycerate kinase 1 OS=Homo sapiens OX=9606 GN=PGK1 PE=1 SV=3 6 1542.7 - 6.22E+06 - - - -4.6202 - 1.377 0.324 - 183.2 1 2 0 -0.0037 7 0 0 0 2.15E+08 1.78E+08 - - - 2.4465 0.9934 221125_WJC_METTL3_EV_vs_WT_F03.04465.04465.2 0.11 12-Jul R.VLDETAR.E sp|Q03252|LMNB2_HUMAN 1 802.4185 1.26 24295 4465 2 802.415797 402.2165 Lamin-B2 OS=Homo sapiens OX=9606 GN=LMNB2 PE=1 SV=4 4.37 1543.2 - 7.10E+06 - - - -3.3461 - 1.521 0.254 - 188.5 1 2 0 -0.0027 7 0 0 0 2.31E+08 1.82E+08 - - - 2.245 0.9935 221125_WJC_METTL3_EV_vs_WT_F03.04493.04493.2 0.103 14-Jun R.LTEGMSGR.E "sp|Q5T9A4|ATD3B_HUMAN,sp|Q9NVI7|ATD3A_HUMAN,tr|Q5SV16|Q5SV16_HUMAN" 3 849.4015 0.71 24301 4493 2 849.399391 425.708 ATPase family AAA domain-containing protein 3B OS=Homo sapiens OX=9606 GN=ATAD3B PE=1 SV=1 6 1547.3 - 456882 - - - -2.4264 - 1.276 0.279 - 59.8 2 2 0 -0.0021 8 0 0 0 1.52E+07 2.15E+07 - - - 1.7017 0.996 221125_WJC_METTL3_EV_vs_WT_F03.04546.04546.2 0.0184 14-May K.VVPVGASR.G "sp|Q9NQ55|SSF1_HUMAN,tr|A0A0B4J1V8|A0A0B4J1V8_HUMAN,tr|A0A0A6YYI3|A0A0A6YYI3_HUMAN,tr|A8MV53|A8MV53_HUMAN,tr|C9J3W3|C9J3W3_HUMAN" 5 783.4603 1.13 24317 4546 2 783.459922 392.7374 Suppressor of SWI4 1 homolog OS=Homo sapiens OX=9606 GN=PPAN PE=2 SV=1 9.72 1554.8 - 984922 - - - -0.4659 - 1.125 0.274 - 87.3 2 2 0 -0.0004 8 0 0 0 4.87E+07 4.31E+07 - - - 1.2854 0.9969 221125_WJC_METTL3_EV_vs_WT_F03.04551.04551.2 0.0353 14-Aug R.VLVNDAQK[136.11].V sp|Q13263|TIF1B_HUMAN 1 893.5062 0.8 24319 4551 2 893.503911 447.7604 Transcription intermediary factor 1-beta OS=Homo sapiens OX=9606 GN=TRIM28 PE=1 SV=5 5.81 1555.4 - 516670 - - - -2.5417 - 1.43 0.309 - 226.6 1 2 0 -0.0023 8 0 0 0 1.30E+08 1.61E+08 - - - 2.4013 0.9987 221125_WJC_METTL3_EV_vs_WT_F03.04568.04568.2 0.0609 14-Sep R.VLVNDAQK.V sp|Q13263|TIF1B_HUMAN 1 885.492 0.8 24325 4568 2 885.489872 443.7533 Transcription intermediary factor 1-beta OS=Homo sapiens OX=9606 GN=TRIM28 PE=1 SV=5 5.81 1557.7 - 3.87E+06 - - - -2.3829 - 1.545 0.374 - 247.4 1 2 0 -0.0021 8 0 0 0 1.30E+08 1.61E+08 - - - 3.1147 0.9044 221125_WJC_METTL3_EV_vs_WT_F03.04576.04576.2 0.73 14-Oct R.GALAEAAR.R "sp|Q96B36|AKTS1_HUMAN,tr|H9KV91|H9KV91_HUMAN" 2 757.4083 0.12 24329 4576 2 758.411252 379.7114 Proline-rich AKT1 substrate 1 OS=Homo sapiens OX=9606 GN=AKT1S1 PE=1 SV=1 6 1558.7 - 1.98E+06 - - - 1324.2528 - 1.791 0.153 - 252.2 1 2 0 1.003 8 0 0 0 4.36E+07 3.75E+08 - - - 1.6137 0.9825 221125_WJC_METTL3_EV_vs_WT_F03.04586.04586.2 0.0312 14-Aug R.LGGAGMER[166.11].M "sp|P52272|HNRPM_HUMAN,tr|A0A087X0X3|A0A087X0X3_HUMAN,tr|M0QZM1|M0QZM1_HUMAN,tr|M0R2T0|M0R2T0_HUMAN" 4 799.3886 1.58 24332 4586 2 799.387454 400.7016 Heterogeneous nuclear ribonucleoprotein M OS=Homo sapiens OX=9606 GN=HNRNPM PE=1 SV=3 6 1560 - 3.69E+06 - - - -1.4248 - 1.618 0.002 - 145.9 1 2 0 -0.0011 8 0 0 0 2.00E+09 1.27E+09 - - - 0.5067 0.8729 221125_WJC_METTL3_EV_vs_WT_F03.04602.04602.2 3.6 12-Jun K.ALETMNK.Y "sp|Q9P2K5|MYEF2_HUMAN,tr|A0A0A0MR39|A0A0A0MR39_HUMAN,tr|A0A087WUT0|A0A087WUT0_HUMAN,tr|A0A0A0MQW0|A0A0A0MQW0_HUMAN" 4 805.4004 1.89 24336 4602 2 805.399067 403.7075 Myelin expression factor 2 OS=Homo sapiens OX=9606 GN=MYEF2 PE=1 SV=3 6.05 1562.4 - 4.31E+06 - - - -1.6414 - 0.961 0.047 - 139.1 1 2 0 -0.0013 7 0 0 0 4.82E+08 2.55E+08 - - - -0.7383 0.9975 221125_WJC_METTL3_EV_vs_WT_F03.04628.04628.2 0.188 12-Jul R.LQATEVR[166.11].L sp|Q9UI30|TR112_HUMAN 1 825.4584 1.24 24345 4628 2 825.457058 413.7365 Multifunctional methyltransferase subunit TRM112-like protein OS=Homo sapiens OX=9606 GN=TRMT112 PE=1 SV=1 6 1565.8 - 1.71E+06 - - - -1.61 - 1.656 0.187 - 243.6 1 2 0 -0.0013 7 0 0 0 2.78E+09 2.25E+09 - - - 2.02 0.9947 221125_WJC_METTL3_EV_vs_WT_F03.04637.04637.2 1.3 12-Jul R.LQATEVR.L sp|Q9UI30|TR112_HUMAN 1 815.4501 1.24 24348 4637 2 815.448712 408.7323 Multifunctional methyltransferase subunit TRM112-like protein OS=Homo sapiens OX=9606 GN=TRMT112 PE=1 SV=1 6 1567 - 6.74E+06 - - - -1.723 - 1.455 0.17 - 179.8 1 2 0 -0.0014 7 0 0 0 2.78E+09 2.25E+09 - - - 1.4844 0.9727 221125_WJC_METTL3_EV_vs_WT_F03.04652.04652.2 0.195 14-Jul R.ELAEEAAR.L sp|Q15149|PLEC_HUMAN 1 887.4349 1.61 24354 4652 2 887.431709 444.7247 Plectin OS=Homo sapiens OX=9606 GN=PLEC PE=1 SV=3 4.25 1569 - 972472 - - - -3.5518 - 1.263 0.202 - 241.4 1 2 0 -0.0032 8 0 0 0 2.16E+07 1.34E+07 - - - 1.2362 0.9952 221125_WJC_METTL3_EV_vs_WT_F03.04667.04667.2 0.0353 16-Jul K.EGVVAAAEK[136.11].T "sp|Q16143|SYUB_HUMAN,sp|P37840|SYUA_HUMAN,tr|A0A669KB41|A0A669KB41_HUMAN,tr|G4Y816|G4Y816_HUMAN,tr|D6RA31|D6RA31_HUMAN,tr|A0A669KBH5|A0A669KBH5_HUMAN,tr|H6UYS7|H6UYS7_HUMAN,tr|E7EPV7|E7EPV7_HUMAN" 8 880.4745 1.72 24359 4667 2 880.471635 441.2445 Beta-synuclein OS=Homo sapiens OX=9606 GN=SNCB PE=1 SV=1 4.53 1571.1 - 1.64E+06 - - - -3.3073 - 1.577 0.291 - 143.6 1 2 0 -0.0029 9 0 0 0 8.71E+08 5.06E+08 - - - 2.5073 0.9992 221125_WJC_METTL3_EV_vs_WT_F03.04672.04672.2 0.0245 12-Jul K.LGDDEVR.T "sp|Q14444|CAPR1_HUMAN,tr|G3V153|G3V153_HUMAN,tr|E9PLA9|E9PLA9_HUMAN" 3 802.3821 0.95 24360 4672 2 802.380546 402.1983 Caprin-1 OS=Homo sapiens OX=9606 GN=CAPRIN1 PE=1 SV=2 4.03 1571.8 - 1.88E+07 - - - -1.933 - 1.583 0.376 - 144.6 1 2 0 -0.0016 7 0 0 0 1.20E+09 1.27E+09 - - - 3.273 0.9984 221125_WJC_METTL3_EV_vs_WT_F03.04679.04679.2 0.0237 12-Jun K.GPDETLR[166.11].L "sp|P22234|PUR6_HUMAN,tr|D6RF62|D6RF62_HUMAN,tr|E9PBS1|E9PBS1_HUMAN" 3 796.3955 1.71 24363 4679 2 796.394331 399.205 Multifunctional protein ADE2 OS=Homo sapiens OX=9606 GN=PAICS PE=1 SV=3 4.37 1572.6 - 4.18E+06 - - - -1.4076 - 1.439 0.285 - 147 1 2 0 -0.0011 7 0 0 0 3.39E+08 1.98E+08 - - - 2.2988 0.9949 221125_WJC_METTL3_EV_vs_WT_F03.04687.04687.2 0.0748 16-Aug K.TIAPQNAPR.D "sp|Q9NYF8|BCLF1_HUMAN,tr|H0YF00|H0YF00_HUMAN,tr|E9PKI6|E9PKI6_HUMAN,tr|A0A1W2PQ43|A0A1W2PQ43_HUMAN,tr|E9PK91|E9PK91_HUMAN,tr|E9PJA7|E9PJA7_HUMAN,tr|E9PK09|E9PK09_HUMAN,tr|E9PQN2|E9PQN2_HUMAN" 8 966.5247 1.04 24366 4687 2 966.525126 484.2696 Bcl-2-associated transcription factor 1 OS=Homo sapiens OX=9606 GN=BCLAF1 PE=1 SV=2 9.41 1573.7 - 302709 - - - 0.4625 - 1.349 0.168 - 162.2 1 2 0 0.0004 9 0 0 0 1.02E+07 9.79E+06 - - - 1.1478 0.9997 221125_WJC_METTL3_EV_vs_WT_F03.04703.04703.2 0.015 12-Jul K.LGDDEVR[166.11].T "sp|Q14444|CAPR1_HUMAN,tr|G3V153|G3V153_HUMAN,tr|E9PLA9|E9PLA9_HUMAN" 3 812.3904 0.95 24371 4703 2 812.389481 407.2025 Caprin-1 OS=Homo sapiens OX=9606 GN=CAPRIN1 PE=1 SV=2 4.03 1575.8 - 3.10E+07 - - - -1.0906 - 1.703 0.424 - 150.8 1 2 0 -0.0009 7 0 0 0 1.20E+09 1.27E+09 - - - 3.8593 0.998 221125_WJC_METTL3_EV_vs_WT_F03.04709.04709.2 0.0968 12-Jul K.VMMEGGR[166.11].S "sp|Q9H361|PABP3_HUMAN,sp|P11940|PABP1_HUMAN,tr|A0A7I2YQE4|A0A7I2YQE4_HUMAN,tr|A0A7I2V649|A0A7I2V649_HUMAN,tr|H0YB86|H0YB86_HUMAN,tr|H0YAR2|H0YAR2_HUMAN,tr|E7ERJ7|E7ERJ7_HUMAN,tr|A0A7I2YQ88|A0A7I2YQ88_HUMAN,tr|A0A087WTT1|A0A087WTT1_HUMAN,tr|A0A7I2YQ90|A0A7I2YQ90_HUMAN,tr|A0A7I2V4N4|A0A7I2V4N4_HUMAN,tr|E7EQV3|E7EQV3_HUMAN" 12 788.3549 1.09 24373 4709 2 788.353603 395.1847 Polyadenylate-binding protein 3 OS=Homo sapiens OX=9606 GN=PABPC3 PE=1 SV=2 5.97 1576.6 - 8.23E+06 - - - -1.5818 - 1.277 0.321 - 226.9 1 2 0 -0.0012 7 0 0 0 5.52E+08 5.04E+08 - - - 2.1863 0.9943 221125_WJC_METTL3_EV_vs_WT_F03.04716.04716.2 0.105 12-Jun K.VMMEGGR.S "sp|Q9H361|PABP3_HUMAN,sp|P11940|PABP1_HUMAN,tr|A0A7I2YQE4|A0A7I2YQE4_HUMAN,tr|A0A7I2V649|A0A7I2V649_HUMAN,tr|H0YB86|H0YB86_HUMAN,tr|H0YAR2|H0YAR2_HUMAN,tr|E7ERJ7|E7ERJ7_HUMAN,tr|A0A7I2YQ88|A0A7I2YQ88_HUMAN,tr|A0A087WTT1|A0A087WTT1_HUMAN,tr|A0A7I2YQ90|A0A7I2YQ90_HUMAN,tr|A0A7I2V4N4|A0A7I2V4N4_HUMAN,tr|E7EQV3|E7EQV3_HUMAN" 12 778.3466 1.09 24376 4716 2 778.345017 390.1806 Polyadenylate-binding protein 3 OS=Homo sapiens OX=9606 GN=PABPC3 PE=1 SV=2 5.97 1577.5 - 1.15E+07 - - - -2.0081 - 1.198 0.265 - 189.1 1 2 0 -0.0016 7 0 0 0 5.52E+08 5.04E+08 - - - 1.5702 0.9987 221125_WJC_METTL3_EV_vs_WT_F03.04725.04725.2 0.02 12-Jun K.MTQAQLR.A "sp|Q16656|NRF1_HUMAN,tr|C9JP85|C9JP85_HUMAN" 2 846.4382 1.14 24378 4725 2 846.438207 424.2264 Nuclear respiratory factor 1 OS=Homo sapiens OX=9606 GN=NRF1 PE=1 SV=1 9.5 1578.8 - 675238 - - - 0.0413 - 1.383 0.283 - 177.5 1 2 0 0 7 0 0 0 1.84E+08 1.61E+08 - - - 2.1586 0.9907 221125_WJC_METTL3_EV_vs_WT_F03.04733.04733.2 0.382 14-Jun R.LVGEDAPK[136.11].N sp|Q9P2D1|CHD7_HUMAN 1 835.4531 1.88 24382 4733 2 835.451284 418.7338 Chromodomain-helicase-DNA-binding protein 7 OS=Homo sapiens OX=9606 GN=CHD7 PE=1 SV=3 4.37 1579.9 - 1.17E+06 - - - -2.1533 - 1.194 0.274 - 113 5 2 0 -0.0018 8 0 0 0 4.44E+08 2.36E+08 - - - 1.2867 0.9987 221125_WJC_METTL3_EV_vs_WT_F03.04745.04745.2 0.00222 12-Jul K.MTQAQLR[166.11].A "sp|Q16656|NRF1_HUMAN,tr|C9JP85|C9JP85_HUMAN" 2 856.4464 1.09 24384 4745 2 856.445332 429.2305 Nuclear respiratory factor 1 OS=Homo sapiens OX=9606 GN=NRF1 PE=1 SV=1 9.5 1581.7 - 1.50E+06 - - - -1.2961 - 1.498 0.289 - 278.9 1 2 0 -0.0011 7 0 0 0 1.86E+08 1.70E+08 - - - 2.4557 0.9996 221125_WJC_METTL3_EV_vs_WT_F03.04747.04747.2 0.0251 12-Jul K.VPVPEDK.Y sp|O75947|ATP5H_HUMAN 1 782.4174 1.77 24385 4747 2 782.417292 392.216 "ATP synthase subunit d, mitochondrial OS=Homo sapiens OX=9606 GN=ATP5PD PE=1 SV=3" 4.37 1582 - 1.05E+07 - - - -0.1636 - 1.617 0.362 - 281.4 1 2 0 -0.0001 7 0 0 0 5.19E+08 2.94E+08 - - - 3.2374 0.7836 221125_WJC_METTL3_EV_vs_WT_F03.04751.04751.2 0.297 14-Aug E.LLNTTTAK[136.11].E "sp|Q86U44|MTA70_HUMAN,tr|H0YFV6|H0YFV6_HUMAN" 2 868.5109 0.68 24386 4751 2 868.509366 435.2627 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 8.75 1582.5 - 6.56E+06 - - - -1.8042 - 1.45 0.2 - 152.5 1 1 0 -0.0016 8 0 0 0 1.95E+08 2.86E+08 - - - 1.6383 0.9861 221125_WJC_METTL3_EV_vs_WT_F03.04768.04768.2 0.195 12-Jul K.LVEESVK.H "sp|P52732|KIF11_HUMAN,tr|A0A7I2V3A9|A0A7I2V3A9_HUMAN" 2 802.4436 4.36 24392 4768 2 802.44233 402.2291 Kinesin-like protein KIF11 OS=Homo sapiens OX=9606 GN=KIF11 PE=1 SV=2 4.53 1584.8 - 3.32E+06 - - - -1.625 - 1.182 0.159 - 121.6 1 2 0 -0.0013 7 0 0 0 7.11E+09 1.63E+09 - - - 0.7448 0.792 221125_WJC_METTL3_EV_vs_WT_F03.04776.04776.2 3.89 12-May K.VPVPEDK[136.11].Y sp|O75947|ATP5H_HUMAN 1 790.4316 2.45 24393 4776 2 790.429833 396.2231 "ATP synthase subunit d, mitochondrial OS=Homo sapiens OX=9606 GN=ATP5PD PE=1 SV=3" 4.37 1586.1 - 1.29E+06 - - - -2.2608 - 0.978 0.026 - 98.9 1 2 0 -0.0018 7 0 0 0 7.33E+08 2.99E+08 - - - -0.838 0.9943 221125_WJC_METTL3_EV_vs_WT_F03.04812.04812.2 0.408 14-Jul K.YLESAGAR.V "sp|Q92820|GGH_HUMAN,tr|A0A7I2YQQ3|A0A7I2YQQ3_HUMAN,tr|A0A7I2V5X9|A0A7I2V5X9_HUMAN,tr|A0A7I2V5P2|A0A7I2V5P2_HUMAN" 4 865.4294 7.42 24399 4812 2 865.428106 433.722 Gamma-glutamyl hydrolase OS=Homo sapiens OX=9606 GN=GGH PE=1 SV=2 6 1591.9 - 1.64E+06 - - - -1.4733 - 1.36 0.182 - 151.7 1 2 0 -0.0013 8 0 0 0 1.04E+08 1.40E+07 - - - 1.3122 0.9483 221125_WJC_METTL3_EV_vs_WT_F03.04824.04824.2 0.44 14-Jul R.EAAELAAR[166.11].G sp|Q9NP08|HMX1_HUMAN 1 839.4377 1.07 24403 4824 2 839.433326 420.7261 Homeobox protein HMX1 OS=Homo sapiens OX=9606 GN=HMX1 PE=2 SV=2 4.53 1593.6 - 687303 - - - -5.1523 - 1.607 0.154 - 186.9 1 2 0 -0.0043 8 0 0 0 1.42E+08 1.33E+08 - - - 1.6078 0.9501 221125_WJC_METTL3_EV_vs_WT_F03.04859.04859.2 0.641 14-Jun R.IIEAEESR.M sp|Q9NVH1|DJC11_HUMAN 1 945.4767 0.97 24412 4859 2 945.473425 473.7456 DnaJ homolog subfamily C member 11 OS=Homo sapiens OX=9606 GN=DNAJC11 PE=1 SV=2 4.25 1598.5 - 344501 - - - -3.4903 - 1.232 0.148 - 130.8 1 2 0 -0.0033 8 0 0 0 2.86E+07 2.95E+07 - - - 0.7623 0.9228 221125_WJC_METTL3_EV_vs_WT_F03.04862.04862.2 1.6 14-Jun R.GVAAPVER[166.11].A sp|Q9HBH1|DEFM_HUMAN 1 807.4478 1.51 24413 4862 2 807.446608 404.7312 "Peptide deformylase, mitochondrial OS=Homo sapiens OX=9606 GN=PDF PE=1 SV=1" 6 1598.9 - 1.00E+07 - - - -1.5035 - 1.252 0.006 - 165.5 3 2 0 -0.0012 8 0 0 0 9.05E+08 6.01E+08 - - - -0.4504 0.9982 221125_WJC_METTL3_EV_vs_WT_F03.04863.04863.2 0.0647 14-Aug R.IIEAEESR[166.11].M sp|Q9NVH1|DJC11_HUMAN 1 955.485 0.97 24414 4863 2 955.484268 478.7498 DnaJ homolog subfamily C member 11 OS=Homo sapiens OX=9606 GN=DNAJC11 PE=1 SV=2 4.25 1599 - 526550 - - - -0.7609 - 1.474 0.253 - 170.7 2 2 0 -0.0007 8 0 0 0 2.87E+07 2.95E+07 - - - 1.9451 0.9972 221125_WJC_METTL3_EV_vs_WT_F03.04865.04865.2 0.237 12-Aug K.ILTTEGR.N sp|Q08211|DHX9_HUMAN 1 788.4392 0.73 24415 4865 2 788.43767 395.2269 ATP-dependent RNA helicase A OS=Homo sapiens OX=9606 GN=DHX9 PE=1 SV=4 6 1599.2 - 1.59E+07 - - - -1.9634 - 1.644 0.205 - 184.4 1 2 0 -0.0015 7 0 0 0 8.70E+08 1.19E+09 - - - 2.1298 0.9981 221125_WJC_METTL3_EV_vs_WT_F03.04880.04880.2 0.247 16-Oct K.LIAAQTGTR.W sp|Q9BZL1|UBL5_HUMAN 1 929.5294 1.56 24419 4880 2 929.528151 465.772 Ubiquitin-like protein 5 OS=Homo sapiens OX=9606 GN=UBL5 PE=1 SV=1 9.75 1601.4 - 924053 - - - -1.376 - 1.648 0.22 - 280.5 1 2 0 -0.0013 9 0 0 0 3.94E+09 2.52E+09 - - - 2.1108 0.9128 221125_WJC_METTL3_EV_vs_WT_F03.04884.04884.2 1.95 14-Jun R.GVAAPVER.A sp|Q9HBH1|DEFM_HUMAN 1 797.4396 1.46 24421 4884 2 797.438082 399.7271 "Peptide deformylase, mitochondrial OS=Homo sapiens OX=9606 GN=PDF PE=1 SV=1" 6 1601.8 - 1.19E+07 - - - -1.8434 - 1.095 0.068 - 106.1 3 2 0 -0.0015 8 0 0 0 9.06E+08 6.23E+08 - - - -0.3966 0.9996 221125_WJC_METTL3_EV_vs_WT_F03.04891.04891.2 0.00155 16-Oct R.TAQAAAALR.R "sp|P51570|GALK1_HUMAN,tr|K7EII7|K7EII7_HUMAN" 2 871.4876 1.84 24424 4891 2 871.486726 436.7511 Galactokinase OS=Homo sapiens OX=9606 GN=GALK1 PE=1 SV=1 9.41 1602.7 - 521637 - - - -0.9627 - 1.714 0.389 - 439.3 1 2 0 -0.0008 9 0 0 0 7.98E+07 4.34E+07 - - - 3.4728 0.9919 221125_WJC_METTL3_EV_vs_WT_F03.04893.04893.2 0.364 12-Jul K.ISDSTLK.T "sp|Q9ULM3|YETS2_HUMAN,sp|O75643|U520_HUMAN,tr|H0Y6M6|H0Y6M6_HUMAN" 3 762.4123 1.47 24425 4893 2 762.411423 382.2134 YEATS domain-containing protein 2 OS=Homo sapiens OX=9606 GN=YEATS2 PE=1 SV=2 5.84 1602.9 - 5.98E+06 - - - -1.1949 - 1.519 0.079 - 124.6 1 2 0 -0.0009 7 0 0 0 2.68E+08 1.82E+08 - - - 0.9488 0.9919 221125_WJC_METTL3_EV_vs_WT_F03.04905.04905.2 0.426 16-Jun K.LLATGSQDR.T "sp|Q12788|TBL3_HUMAN,tr|J3KNP2|J3KNP2_HUMAN,tr|A0A087WYP7|A0A087WYP7_HUMAN" 3 959.5036 1.13 24428 4905 2 959.503964 480.7591 Transducin beta-like protein 3 OS=Homo sapiens OX=9606 GN=TBL3 PE=1 SV=2 5.84 1604.7 - 380098 - - - 0.37 - 1.251 0.15 - 95.1 1 2 0 0.0004 9 0 0 0 6.59E+07 5.85E+07 - - - 0.7967 0.9995 221125_WJC_METTL3_EV_vs_WT_F03.04909.04909.2 0.000331 16-Oct R.TAQAAAALR[166.11].R "sp|P51570|GALK1_HUMAN,tr|K7EII7|K7EII7_HUMAN" 2 881.4958 1.85 24429 4909 2 881.494232 441.7552 Galactokinase OS=Homo sapiens OX=9606 GN=GALK1 PE=1 SV=1 9.41 1605.4 - 682631 - - - -1.8185 - 1.771 0.426 - 460 1 2 0 -0.0016 9 0 0 0 7.97E+07 4.31E+07 - - - 3.8404 0.9283 221125_WJC_METTL3_EV_vs_WT_F03.04914.04914.2 0.323 12-Jun R.EIQTAVR.L "sp|P33778|H2B1B_HUMAN,sp|Q96A08|H2B1A_HUMAN,sp|Q5QNW6|H2B2F_HUMAN,sp|P58876|H2B1D_HUMAN,sp|Q99880|H2B1L_HUMAN,sp|P62807|H2B1C_HUMAN,sp|Q99877|H2B1N_HUMAN,sp|P57053|H2BFS_HUMAN,sp|P23527|H2B1O_HUMAN,sp|O60814|H2B1K_HUMAN,sp|Q93079|H2B1H_HUMAN,sp|Q99879|H2B1M_HUMAN,sp|Q16778|H2B2E_HUMAN,sp|P06899|H2B1J_HUMAN,tr|U3KQK0|U3KQK0_HUMAN" 15 815.4501 1.01 24431 4914 2 815.448148 408.7323 Histone H2B type 1-B OS=Homo sapiens OX=9606 GN=H2BC3 PE=1 SV=2 6.1 1606 - 3.67E+07 - - - -2.4146 - 1.273 0.025 - 227.8 1 2 0 -0.002 7 0 0 0 6.24E+09 6.18E+09 - - - -0.0102 0.8449 221125_WJC_METTL3_EV_vs_WT_F03.04923.04923.2 1.67 14-Jun R.AMAQTAIK[136.11].A "sp|Q92879|CELF1_HUMAN,tr|G5EA30|G5EA30_HUMAN" 2 840.4619 0.81 24433 4923 2 840.458631 421.2382 CUGBP Elav-like family member 1 OS=Homo sapiens OX=9606 GN=CELF1 PE=1 SV=2 8.8 1607.3 - 1.50E+06 - - - -3.8586 - 1.288 0.071 - 102.8 3 2 0 -0.0032 8 0 0 0 9.82E+07 1.21E+08 - - - 0.1146 1 221125_WJC_METTL3_EV_vs_WT_F03.04932.04932.3 1.58E-07 14/52 K.K[136.11]GPGEVAGTVTGQK[136.11].R "sp|Q86U44|MTA70_HUMAN,tr|F5H6D8|F5H6D8_HUMAN,tr|H0YFV6|H0YFV6_HUMAN,tr|B4DTN4|B4DTN4_HUMAN" 4 1343.738 0 24436 4932 3 1343.734879 448.9199 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 8.59 1608.5 - 711949 - - - -2.307 - 2.751 0.537 - 282 1 2 0 -0.0031 14 0 0 0 6.93E+05 4.81E+08 - - - 7.2155 0.9972 221125_WJC_METTL3_EV_vs_WT_F03.04943.04943.2 0.248 14-Jul K.AVVAQAVR.H sp|O94906|PRP6_HUMAN 1 812.4868 1.98 24443 4943 2 812.485331 407.2507 Pre-mRNA-processing factor 6 OS=Homo sapiens OX=9606 GN=PRPF6 PE=1 SV=1 9.79 1609.9 - 3.46E+06 - - - -1.8536 - 1.652 0.205 - 187.4 1 2 0 -0.0015 8 0 0 0 3.87E+08 1.96E+08 - - - 2.0686 0.9999 221125_WJC_METTL3_EV_vs_WT_F03.04951.04951.2 1.40E-05 24-Sep R.FSSSSGYGGGSSR.V sp|P35527|K1C9_HUMAN 1 1234.5214 999 24446 4951 2 1234.520364 618.268 "Keratin, type I cytoskeletal 9 OS=Homo sapiens OX=9606 GN=KRT9 PE=1 SV=3" 8.75 1611 - 358331 - - - -0.8748 - 1.974 0.588 - 207.6 1 2 0 -0.0011 13 0 0 0 1.75E+07 0.00E+00 - - - 5.129 0.9428 221125_WJC_METTL3_EV_vs_WT_F03.04954.04954.2 3.92 14-Jul R.AMAQTAIK.A "sp|Q92879|CELF1_HUMAN,tr|G5EA30|G5EA30_HUMAN" 2 832.4477 0.83 24447 4954 2 832.445944 417.2311 CUGBP Elav-like family member 1 OS=Homo sapiens OX=9606 GN=CELF1 PE=1 SV=2 8.8 1611.3 - 2.72E+06 - - - -2.0782 - 1.154 0.07 - 175.7 1 2 0 -0.0017 8 0 0 0 9.82E+07 1.19E+08 - - - -0.0105 0.9994 221125_WJC_METTL3_EV_vs_WT_F03.04957.04957.2 0.00329 12-Jun R.MMMQSGR[166.11].K "sp|P12235|ADT1_HUMAN,sp|P05141|ADT2_HUMAN,sp|P12236|ADT3_HUMAN" 3 849.3535 0.81 24448 4957 2 849.351787 425.684 ADP\ATP translocase 1 OS=Homo sapiens OX=9606 GN=SLC25A4 PE=1 SV=4 9.5 1611.7 - 3.19E+06 - - - -1.9803 - 1.287 0.503 - 143.4 1 2 0 -0.0017 7 0 0 0 1.31E+08 1.62E+08 - - - 3.5551 0.9978 221125_WJC_METTL3_EV_vs_WT_F03.04960.04960.2 0.0205 12-May R.MMMQSGR.K "sp|P12235|ADT1_HUMAN,sp|P05141|ADT2_HUMAN,sp|P12236|ADT3_HUMAN" 3 839.3452 0.81 24449 4960 2 839.343339 420.6799 ADP\ATP translocase 1 OS=Homo sapiens OX=9606 GN=SLC25A4 PE=1 SV=4 9.5 1612.1 - 1.95E+06 - - - -2.216 - 1.309 0.35 - 128.6 1 2 0 -0.0019 7 0 0 0 1.31E+08 1.62E+08 - - - 2.4787 0.9998 221125_WJC_METTL3_EV_vs_WT_F03.04979.04979.2 5.46E-08 26-Nov K.K[136.11]GPGEVAGTVTGQK[136.11].R "sp|Q86U44|MTA70_HUMAN,tr|F5H6D8|F5H6D8_HUMAN,tr|H0YFV6|H0YFV6_HUMAN,tr|B4DTN4|B4DTN4_HUMAN" 4 1343.738 0.001 24455 4979 2 1343.735316 672.8763 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 8.59 1614.9 - 299826 - - - -1.9818 - 2.452 0.536 - 202.6 1 2 0 -0.0027 14 0 0 0 0.00E+00 7.82E+07 - - - 5.2498 0.9992 221125_WJC_METTL3_EV_vs_WT_F03.04983.04983.2 0.00121 14-Aug K.EHC[160.03]LVGVK[136.11].G sp|Q86U44|MTA70_HUMAN 1 948.4942 0.04 24456 4983 2 948.49169 475.2544 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 6.83 1615.5 - 1.43E+06 - - - -2.6853 - 1.689 0.443 - 188.2 1 2 0 -0.0025 8 0 0 0 8.56E+06 2.42E+08 - - - 3.893 0.9703 221125_WJC_METTL3_EV_vs_WT_F03.05001.05001.2 3.15 12-Jul R.NLAPTPR.R sp|Q8IU81|I2BP1_HUMAN 1 767.429 1.43 24459 5001 2 767.429154 384.7218 Interferon regulatory factor 2-binding protein 1 OS=Homo sapiens OX=9606 GN=IRF2BP1 PE=1 SV=1 9.75 1618.3 - 4.17E+06 - - - 0.2176 - 1.305 0.004 - 274.5 1 2 0 0.0002 7 0 0 0 2.39E+08 1.67E+08 - - - -0.086 0.999 221125_WJC_METTL3_EV_vs_WT_F03.05008.05008.2 0.00613 14-Aug K.TAAEDAIR.N "sp|Q9BWF3|RBM4_HUMAN,sp|Q9BQ04|RBM4B_HUMAN,tr|E9PM61|E9PM61_HUMAN,tr|D6R9K7|D6R9K7_HUMAN,tr|J3QRR5|J3QRR5_HUMAN,tr|E9PB51|E9PB51_HUMAN,tr|U3KQD5|U3KQD5_HUMAN,tr|E9PLB0|E9PLB0_HUMAN" 8 845.4243 2.06 24461 5008 2 845.424366 423.7194 RNA-binding protein 4 OS=Homo sapiens OX=9606 GN=RBM4 PE=1 SV=1 4.37 1619.4 - 1.25E+06 - - - 0.0828 - 1.579 0.269 - 258.6 1 2 0 0.0001 8 0 0 0 2.44E+08 1.19E+08 - - - 2.4055 0.9727 221125_WJC_METTL3_EV_vs_WT_F03.05014.05014.2 0.00298 18-Aug N.IIPASTGAAK.A "sp|O14556|G3PT_HUMAN,sp|P04406|G3P_HUMAN,tr|E7EUT5|E7EUT5_HUMAN" 3 927.5389 1.02 24463 5014 2 927.539004 464.7767 "Glyceraldehyde-3-phosphate dehydrogenase, testis-specific OS=Homo sapiens OX=9606 GN=GAPDHS PE=1 SV=2" 8.75 1620.2 - 2.56E+06 - - - 0.0776 - 1.262 0.461 - 163.2 1 1 0 0.0001 10 0 0 0 2.71E+08 2.65E+08 - - - 3.0955 0.9988 221125_WJC_METTL3_EV_vs_WT_F03.05024.05024.2 0.115 14-Oct K.TAAEDAIR[166.11].N "sp|Q9BWF3|RBM4_HUMAN,sp|Q9BQ04|RBM4B_HUMAN,tr|E9PM61|E9PM61_HUMAN,tr|D6R9K7|D6R9K7_HUMAN,tr|J3QRR5|J3QRR5_HUMAN,tr|E9PB51|E9PB51_HUMAN,tr|U3KQD5|U3KQD5_HUMAN,tr|E9PLB0|E9PLB0_HUMAN" 8 855.4326 2.33 24466 5024 2 855.432457 428.7236 RNA-binding protein 4 OS=Homo sapiens OX=9606 GN=RBM4 PE=1 SV=1 4.37 1621.6 - 2.28E+06 - - - -0.1274 - 1.812 0.181 - 427.8 1 2 0 -0.0001 8 0 0 0 2.80E+08 1.20E+08 - - - 2.1706 0.9622 221125_WJC_METTL3_EV_vs_WT_F03.05051.05051.2 0.00664 18-Aug N.IIPASTGAAK[136.11].A "sp|O14556|G3PT_HUMAN,sp|P04406|G3P_HUMAN,tr|E7EUT5|E7EUT5_HUMAN" 3 935.5531 1.02 24477 5051 2 935.553322 468.7838 "Glyceraldehyde-3-phosphate dehydrogenase, testis-specific OS=Homo sapiens OX=9606 GN=GAPDHS PE=1 SV=2" 8.75 1625.2 - 2.74E+06 - - - 0.2031 - 1.565 0.337 - 180.5 1 1 0 0.0002 10 0 0 0 2.71E+08 2.65E+08 - - - 2.7802 0.9875 221125_WJC_METTL3_EV_vs_WT_F03.05055.05055.2 1.9 12-Jul R.IAQQLER.E "sp|Q96FZ7|CHMP6_HUMAN,sp|Q66GS9|CP135_HUMAN,tr|I3L4A1|I3L4A1_HUMAN" 3 856.4767 1.31 24479 5055 2 856.477344 429.2456 Charged multivesicular body protein 6 OS=Homo sapiens OX=9606 GN=CHMP6 PE=1 SV=3 6 1625.7 - 2.64E+06 - - - 0.7916 - 1.303 0.097 - 215.3 1 2 0 0.0007 7 0 0 0 3.48E+08 2.66E+08 - - - 0.5958 0.9984 221125_WJC_METTL3_EV_vs_WT_F03.05091.05091.2 0.0901 12-Jul R.LSYGEAK.K "sp|P55265|DSRAD_HUMAN,tr|A0A3B3IRQ9|A0A3B3IRQ9_HUMAN,tr|A0A7P0Z4K3|A0A7P0Z4K3_HUMAN,tr|A0A7P0Z4F9|A0A7P0Z4F9_HUMAN" 4 766.3861 0.67 24489 5091 2 766.386783 384.2003 Double-stranded RNA-specific adenosine deaminase OS=Homo sapiens OX=9606 GN=ADAR PE=1 SV=4 6 1631.2 - 1.13E+06 - - - 0.8664 - 1.385 0.28 - 129.7 1 2 0 0.0007 7 0 0 0 1.09E+09 1.62E+09 - - - 2.1409 0.9996 221125_WJC_METTL3_EV_vs_WT_F03.05098.05098.2 8.70E-05 16-Oct M.PAPAATYER[166.11].V sp|O95059|RPP14_HUMAN 1 984.4904 0.99 24490 5098 2 984.492049 493.2525 Ribonuclease P protein subunit p14 OS=Homo sapiens OX=9606 GN=RPP14 PE=1 SV=3 6.43 1632.4 - 764786 - - - 1.6597 - 1.968 0.426 - 348.8 1 2 0 0.0016 9 0 0 0 4.23E+07 4.26E+07 - - - 4.1456 0.956 221125_WJC_METTL3_EV_vs_WT_F03.05101.05101.2 5.6 12-Jul R.LSYGEAK[136.11].K "sp|P55265|DSRAD_HUMAN,tr|A0A3B3IRQ9|A0A3B3IRQ9_HUMAN,tr|A0A7P0Z4K3|A0A7P0Z4K3_HUMAN,tr|A0A7P0Z4F9|A0A7P0Z4F9_HUMAN" 4 774.4003 0.16 24491 5101 2 774.402844 388.2074 Double-stranded RNA-specific adenosine deaminase OS=Homo sapiens OX=9606 GN=ADAR PE=1 SV=4 6 1632.8 - 5.73E+06 - - - 3.2606 - 1.182 0.16 - 145.1 1 2 0 0.0025 7 0 0 0 3.93E+08 2.44E+09 - - - 0.7518 0.9997 221125_WJC_METTL3_EV_vs_WT_F03.05102.05102.2 0.00857 16-Sep M.PAPAATYER.V sp|O95059|RPP14_HUMAN 1 974.4821 0.99 24492 5102 2 974.482453 488.2483 Ribonuclease P protein subunit p14 OS=Homo sapiens OX=9606 GN=RPP14 PE=1 SV=3 6.43 1632.9 - 760511 - - - 0.3161 - 1.615 0.42 - 170.2 1 2 0 0.0003 9 0 0 0 4.24E+07 4.27E+07 - - - 3.5298 0.9354 221125_WJC_METTL3_EV_vs_WT_F03.05108.05108.2 4.36 12-May K.VIMATNR.L "sp|P62195|PRS8_HUMAN,sp|P35998|PRS7_HUMAN,sp|P43686|PRS6B_HUMAN,sp|P62191|PRS4_HUMAN,tr|C9JX88|C9JX88_HUMAN" 5 803.4324 0.7 24493 5108 2 803.433892 402.7235 26S proteasome regulatory subunit 8 OS=Homo sapiens OX=9606 GN=PSMC5 PE=1 SV=1 9.72 1633.9 - 2.56E+06 - - - 1.9093 - 1.068 0.104 - 82.9 2 2 0 0.0015 7 0 0 0 2.72E+08 3.88E+08 - - - -0.1174 0.9321 221125_WJC_METTL3_EV_vs_WT_F03.05114.05114.2 0.605 16-Jun R.IVSGAYDGK.L "sp|Q9Y297|FBW1A_HUMAN,sp|Q9UKB1|FBW1B_HUMAN,tr|E5RGC1|E5RGC1_HUMAN,tr|B7Z3H4|B7Z3H4_HUMAN" 4 908.4603 0.78 24497 5114 2 908.462017 455.2374 F-box\WD repeat-containing protein 1A OS=Homo sapiens OX=9606 GN=BTRC PE=1 SV=1 5.83 1634.6 - 714449 - - - 1.8383 - 1.051 0.115 - 54.2 3 2 0 0.0017 9 0 0 0 3.15E+07 4.04E+07 - - - -0.1794 0.9887 221125_WJC_METTL3_EV_vs_WT_F03.05122.05122.2 0.981 12-Jun K.VIMATNR[166.11].L "sp|P62195|PRS8_HUMAN,sp|P35998|PRS7_HUMAN,sp|P43686|PRS6B_HUMAN,sp|P62191|PRS4_HUMAN,tr|C9JX88|C9JX88_HUMAN" 5 813.4406 0.7 24500 5122 2 813.441191 407.7276 26S proteasome regulatory subunit 8 OS=Homo sapiens OX=9606 GN=PSMC5 PE=1 SV=1 9.72 1635.8 - 8.13E+06 - - - 0.6921 - 1.07 0.187 - 158.9 1 2 0 0.0006 7 0 0 0 2.72E+08 3.89E+08 - - - 0.6364 0.9671 221125_WJC_METTL3_EV_vs_WT_F03.05123.05123.2 8.18 12-Aug R.SIVNQVR[166.11].F sp|Q96JK2|DCAF5_HUMAN 1 824.4744 1.07 24501 5123 2 824.473246 413.2445 DDB1- and CUL4-associated factor 5 OS=Homo sapiens OX=9606 GN=DCAF5 PE=1 SV=2 9.47 1636 - 539528 - - - -1.3645 - 1.398 0.031 - 197.3 4 2 0 -0.0011 7 0 0 0 1.58E+07 1.48E+07 - - - 0.0623 0.9803 221125_WJC_METTL3_EV_vs_WT_F03.05126.05126.2 0.344 14-Sep K.TDAAVEMK[136.11].R "sp|Q16643|DREB_HUMAN,tr|D6R9W4|D6R9W4_HUMAN" 2 871.4201 0.66 24502 5126 2 871.419277 436.7173 Drebrin OS=Homo sapiens OX=9606 GN=DBN1 PE=1 SV=4 4.37 1636.4 - 647451 - - - -0.9089 - 1.253 0.073 - 159.4 1 2 0 -0.0008 8 0 0 0 1.64E+07 2.46E+07 - - - 0.2601 0.9938 221125_WJC_METTL3_EV_vs_WT_F03.05127.05127.2 0.176 16-Jun R.QVDQLTNDK.A "sp|P08670|VIME_HUMAN,tr|B0YJC4|B0YJC4_HUMAN" 2 1059.5197 2.17 24503 5127 2 1059.521691 530.7671 Vimentin OS=Homo sapiens OX=9606 GN=VIM PE=1 SV=4 4.21 1636.5 - 264718 - - - 1.9235 - 1.35 0.238 - 67.9 2 2 0 0.002 9 0 0 0 9.09E+06 4.20E+06 - - - 1.532 0.8899 221125_WJC_METTL3_EV_vs_WT_F03.05131.05131.2 8.16 12-Jun R.LLADQER.R sp|O95613|PCNT_HUMAN 1 843.445 0.83 24505 5131 2 843.446429 422.7298 Pericentrin OS=Homo sapiens OX=9606 GN=PCNT PE=1 SV=4 4.37 1637.1 - 433636 - - - 1.6575 - 1.055 0.029 - 113.1 1 2 0 0.0014 7 0 0 0 3.35E+07 4.04E+07 - - - -0.5756 0.996 221125_WJC_METTL3_EV_vs_WT_F03.05140.05140.2 0.0686 14-Apr R.EPADAAIR.E sp|P33908|MA1A1_HUMAN 1 841.4294 3 24508 5140 2 841.429251 421.722 "Mannosyl-oligosaccharide 1,2-alpha-mannosidase IA OS=Homo sapiens OX=9606 GN=MAN1A1 PE=1 SV=3" 4.37 1638.3 - 1.17E+06 - - - -0.1545 - 1.226 0.245 - 87.1 3 2 0 -0.0001 8 0 0 0 1.46E+08 4.86E+07 - - - 1.2519 1 221125_WJC_METTL3_EV_vs_WT_F03.05143.05143.3 2.49E-07 14/52 K.K[136.11]GPGEVAGTVTGQK[136.11].R "sp|Q86U44|MTA70_HUMAN,tr|F5H6D8|F5H6D8_HUMAN,tr|H0YFV6|H0YFV6_HUMAN,tr|B4DTN4|B4DTN4_HUMAN" 4 1343.738 0 24509 5143 3 1343.739574 448.9199 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 8.59 1638.7 - 2.30E+06 - - - 1.187 - 2.932 0.486 - 337.1 1 2 0 0.0016 14 0 0 0 6.93E+05 4.60E+08 - - - 6.8166 0.9967 221125_WJC_METTL3_EV_vs_WT_F03.05159.05159.2 0.147 14-Jul K.LLTEEGQK[136.11].L sp|Q6NUK1|SCMC1_HUMAN 1 924.5008 1.22 24515 5159 2 924.500445 463.2577 Calcium-binding mitochondrial carrier protein SCaMC-1 OS=Homo sapiens OX=9606 GN=SLC25A24 PE=1 SV=2 4.53 1641 - 448418 - - - -0.3429 - 1.266 0.223 - 115.5 1 2 0 -0.0003 8 0 0 0 4.14E+07 3.39E+07 - - - 1.3993 0.9928 221125_WJC_METTL3_EV_vs_WT_F03.05175.05175.2 0.267 12-Jun R.LTPTEVK[136.11].D "sp|P25787|PSA2_HUMAN,tr|A0A024RA52|A0A024RA52_HUMAN,tr|C9JCK5|C9JCK5_HUMAN,tr|A0A7I2YQP7|A0A7I2YQP7_HUMAN" 4 794.4629 0.62 24519 5175 2 794.46361 398.2387 Proteasome subunit alpha type-2 OS=Homo sapiens OX=9606 GN=PSMA2 PE=1 SV=2 6 1643.5 - 1.59E+06 - - - 0.8685 - 1.238 0.173 - 127.5 1 2 0 0.0007 7 0 0 0 8.13E+07 1.30E+08 - - - 0.995 0.9934 221125_WJC_METTL3_EV_vs_WT_F03.05176.05176.2 0.686 12-Jun R.LTPTEVK.D "sp|P25787|PSA2_HUMAN,tr|A0A024RA52|A0A024RA52_HUMAN,tr|C9JCK5|C9JCK5_HUMAN,tr|A0A7I2YQP7|A0A7I2YQP7_HUMAN" 4 786.4487 0.66 24520 5176 2 786.44851 394.2316 Proteasome subunit alpha type-2 OS=Homo sapiens OX=9606 GN=PSMA2 PE=1 SV=2 6 1643.5 - 807899 - - - -0.267 - 1.226 0.165 - 138.3 1 2 0 -0.0002 7 0 0 0 8.87E+07 1.34E+08 - - - 0.9052 0.9627 221125_WJC_METTL3_EV_vs_WT_F03.05180.05180.2 3.37 12-Jun R.LMSTVEK.T "sp|Q6ULP2|AFTIN_HUMAN,tr|A0A0A0MSN6|A0A0A0MSN6_HUMAN,tr|B8ZZI9|B8ZZI9_HUMAN" 3 806.4208 0.24 24521 5180 2 806.421171 404.2177 Aftiphilin OS=Homo sapiens OX=9606 GN=AFTPH PE=1 SV=3 6 1644.1 - 1.12E+06 - - - 0.4725 - 1.053 0.081 - 102 1 2 0 0.0004 7 0 0 0 4.24E+07 1.73E+08 - - - -0.1972 0.9985 221125_WJC_METTL3_EV_vs_WT_F03.05184.05184.2 0.0679 14-Jul K.VPMTSGVK.Q "sp|P16615|AT2A2_HUMAN,tr|H7C5W9|H7C5W9_HUMAN" 2 817.4368 1.23 24523 5184 2 817.436803 409.7257 Sarcoplasmic\endoplasmic reticulum calcium ATPase 2 OS=Homo sapiens OX=9606 GN=ATP2A2 PE=1 SV=1 8.72 1644.7 - 869229 - - - 0.0343 - 1.375 0.29 - 151.7 2 2 0 0 8 0 0 0 8.75E+07 7.13E+07 - - - 2.0089 0.9844 221125_WJC_METTL3_EV_vs_WT_F03.05185.05185.2 0.55 14-Jun K.AVIETADR[166.11].A sp|Q08752|PPID_HUMAN 1 883.4639 1.59 24524 5185 2 883.463619 442.7392 Peptidyl-prolyl cis-trans isomerase D OS=Homo sapiens OX=9606 GN=PPID PE=1 SV=3 4.37 1644.8 - 979082 - - - -0.2796 - 1.257 0.116 - 151.5 4 2 0 -0.0002 8 0 0 0 9.61E+07 6.03E+07 - - - 0.3186 0.9943 221125_WJC_METTL3_EV_vs_WT_F03.05189.05189.2 0.344 12-Jun K.VLVEDTK[136.11].V sp|Q9Y490|TLN1_HUMAN 1 810.4578 1.8 24526 5189 2 810.457481 406.2362 Talin-1 OS=Homo sapiens OX=9606 GN=TLN1 PE=1 SV=3 4.37 1645.4 - 1.12E+06 - - - -0.4356 - 1.238 0.177 - 128.9 1 2 0 -0.0004 7 0 0 0 7.85E+07 4.37E+07 - - - 1.0247 0.9715 221125_WJC_METTL3_EV_vs_WT_F03.05194.05194.2 10.1 12-Jun K.AVVVC[160.03]PK[136.11].D "sp|Q00839|HNRPU_HUMAN,tr|A0A1W2PQL0|A0A1W2PQL0_HUMAN,tr|A0A1W2PPL4|A0A1W2PPL4_HUMAN,tr|A0A1W2PQ74|A0A1W2PQ74_HUMAN,tr|Q5RI18|Q5RI18_HUMAN,tr|A0A1W2PP35|A0A1W2PP35_HUMAN,tr|A0A1W2PPS1|A0A1W2PPS1_HUMAN,tr|A0A1W2PRZ7|A0A1W2PRZ7_HUMAN,tr|A0A1W2PPH7|A0A1W2PPH7_HUMAN,tr|A0A1W2PQD4|A0A1W2PQD4_HUMAN,tr|A0A1W2PP34|A0A1W2PP34_HUMAN,tr|A0A1X7SBS1|A0A1X7SBS1_HUMAN" 12 779.4455 0.95 24527 5194 2 779.442861 390.73 Heterogeneous nuclear ribonucleoprotein U OS=Homo sapiens OX=9606 GN=HNRNPU PE=1 SV=6 8.27 1646.1 - 1.35E+07 - - - -3.3806 - 1.201 0.202 - 177.8 1 2 0 -0.0026 7 0 0 0 7.32E+09 7.71E+09 - - - 1.1125 0.9974 221125_WJC_METTL3_EV_vs_WT_F03.05196.05196.2 0.227 16-Sep R.VAEVAPEER[166.11].E sp|Q6IQ49|SDE2_HUMAN 1 1008.5115 1.57 24528 5196 2 1008.514209 505.263 Replication stress response regulator SDE2 OS=Homo sapiens OX=9606 GN=SDE2 PE=1 SV=1 4.25 1646.4 - 331671 - - - 2.6415 - 1.87 0.244 - 278.1 1 2 0 0.0027 9 0 0 0 1.68E+07 1.07E+07 - - - 2.6532 0.9201 221125_WJC_METTL3_EV_vs_WT_F03.05198.05198.2 3.61 12-Jun K.LEADYDK[136.11].K sp|Q92900|RENT1_HUMAN 1 860.4007 0.35 24529 5198 2 860.402621 431.2076 Regulator of nonsense transcripts 1 OS=Homo sapiens OX=9606 GN=UPF1 PE=1 SV=2 4.03 1646.6 - 418930 - - - 2.2176 - 0.978 0.139 - 81.5 2 2 0 0.0019 7 0 0 0 1.33E+07 3.82E+07 - - - -0.1379 0.9954 221125_WJC_METTL3_EV_vs_WT_F03.05208.05208.2 0.403 16-Jul R.VAEVAPEER.E sp|Q6IQ49|SDE2_HUMAN 1 998.5033 1.41 24533 5208 2 998.503934 500.2589 Replication stress response regulator SDE2 OS=Homo sapiens OX=9606 GN=SDE2 PE=1 SV=1 4.25 1647.9 - 514081 - - - 0.66 - 1.363 0.179 - 156.2 1 2 0 0.0007 9 0 0 0 1.74E+07 1.23E+07 - - - 1.2588 0.9998 221125_WJC_METTL3_EV_vs_WT_F03.05211.05211.2 0.000637 14-Sep K.QMMEAATR.Q sp|O43395|PRPF3_HUMAN 1 936.4157 2.14 24534 5211 2 936.415998 469.2151 U4\U6 small nuclear ribonucleoprotein Prp3 OS=Homo sapiens OX=9606 GN=PRPF3 PE=1 SV=2 6 1648.3 - 1.47E+06 - - - 0.2947 - 1.636 0.464 - 334.9 1 2 0 0.0003 8 0 0 0 2.26E+08 1.06E+08 - - - 3.9526 0.8938 221125_WJC_METTL3_EV_vs_WT_F03.05212.05212.2 6.94 16-Jul K.ILEGTETTK[136.11].Y "sp|P82650|RT22_HUMAN,tr|G5E9W7|G5E9W7_HUMAN,tr|A0A7P0MKV3|A0A7P0MKV3_HUMAN,tr|H7C5F2|H7C5F2_HUMAN,tr|H7C5H3|H7C5H3_HUMAN" 5 998.5375 1.63 24535 5212 2 998.538589 500.276 "28S ribosomal protein S22, mitochondrial OS=Homo sapiens OX=9606 GN=MRPS22 PE=1 SV=1" 4.53 1648.4 - 574092 - - - 1.0495 - 1.05 0.009 - 106.9 1 2 0 0.001 9 0 0 0 3.03E+07 1.86E+07 - - - -0.7517 0.9971 221125_WJC_METTL3_EV_vs_WT_F03.05213.05213.2 0.234 16-Jun K.MLSC[160.03]AGADR.L "sp|P27635|RL10_HUMAN,sp|Q96L21|RL10L_HUMAN,tr|H7C123|H7C123_HUMAN,tr|H7C2C5|H7C2C5_HUMAN,tr|F8W7C6|F8W7C6_HUMAN,tr|A6QRI9|A6QRI9_HUMAN,tr|B8A6G2|B8A6G2_HUMAN,tr|X1WI28|X1WI28_HUMAN" 8 979.4215 0.97 24536 5213 2 979.421919 490.718 60S ribosomal protein L10 OS=Homo sapiens OX=9606 GN=RPL10 PE=1 SV=4 5.59 1648.5 - 250313 - - - 0.391 - 1.203 0.268 - 86.2 1 2 0 0.0004 9 0 0 0 1.30E+08 1.34E+08 - - - 1.555 0.9952 221125_WJC_METTL3_EV_vs_WT_F03.05215.05215.2 0.289 12-Jul K.AVVVC[160.03]PK.D "sp|Q00839|HNRPU_HUMAN,tr|A0A1W2PQL0|A0A1W2PQL0_HUMAN,tr|A0A1W2PPL4|A0A1W2PPL4_HUMAN,tr|A0A1W2PQ74|A0A1W2PQ74_HUMAN,tr|Q5RI18|Q5RI18_HUMAN,tr|A0A1W2PP35|A0A1W2PP35_HUMAN,tr|A0A1W2PPS1|A0A1W2PPS1_HUMAN,tr|A0A1W2PRZ7|A0A1W2PRZ7_HUMAN,tr|A0A1W2PPH7|A0A1W2PPH7_HUMAN,tr|A0A1W2PQD4|A0A1W2PQD4_HUMAN,tr|A0A1W2PP34|A0A1W2PP34_HUMAN,tr|A0A1X7SBS1|A0A1X7SBS1_HUMAN" 12 771.4313 0.95 24537 5215 2 771.431525 386.7229 Heterogeneous nuclear ribonucleoprotein U OS=Homo sapiens OX=9606 GN=HNRNPU PE=1 SV=6 8.27 1648.8 - 2.59E+07 - - - 0.2969 - 1.225 0.199 - 224.8 1 2 0 0.0002 7 0 0 0 7.33E+09 7.71E+09 - - - 1.1538 0.9905 221125_WJC_METTL3_EV_vs_WT_F03.05223.05223.2 1.24 14-Jul K.LLAAC[160.03]SQR[166.11].E sp|Q9BST9|RTKN_HUMAN 1 927.4836 2.29 24541 5223 2 927.482328 464.7491 Rhotekin OS=Homo sapiens OX=9606 GN=RTKN PE=1 SV=2 8.25 1649.8 - 342984 - - - -1.324 - 1.319 0.137 - 146.8 1 2 0 -0.0012 8 0 0 0 2.66E+07 1.16E+07 - - - 0.8875 0.9901 221125_WJC_METTL3_EV_vs_WT_F03.05237.05237.2 1.76 14-Jul K.IAPETAVK[136.11].F sp|Q6NUK1|SCMC1_HUMAN 1 835.4895 1.08 24546 5237 2 835.488203 418.752 Calcium-binding mitochondrial carrier protein SCaMC-1 OS=Homo sapiens OX=9606 GN=SLC25A24 PE=1 SV=2 6 1651.8 - 611449 - - - -1.5153 - 1.551 0.077 - 142.1 1 2 0 -0.0013 8 0 0 0 6.13E+07 5.69E+07 - - - 0.933 0.9502 221125_WJC_METTL3_EV_vs_WT_F03.05241.05241.2 6.97 14-Jun K.IAPESAIK.F "sp|Q6KCM7|SCMC2_HUMAN,sp|Q9BV35|SCMC3_HUMAN,tr|M0QZJ5|M0QZJ5_HUMAN,tr|A0A804HLB0|A0A804HLB0_HUMAN,tr|M0QZP9|M0QZP9_HUMAN,tr|M0R1W8|M0R1W8_HUMAN,tr|M0QZT4|M0QZT4_HUMAN,tr|A0A804HI56|A0A804HI56_HUMAN" 8 827.4753 1.08 24547 5241 2 827.475112 414.7449 Calcium-binding mitochondrial carrier protein SCaMC-2 OS=Homo sapiens OX=9606 GN=SLC25A25 PE=1 SV=1 6 1652.4 - 599040 - - - -0.1897 - 1.045 0.089 - 79.3 4 2 0 -0.0002 8 0 0 0 6.13E+07 5.69E+07 - - - -0.4379 0.9978 221125_WJC_METTL3_EV_vs_WT_F03.05254.05254.2 0.0406 14-Jul R.NPAELAEK.S sp|P0C7T5|ATX1L_HUMAN 1 870.4447 0.3 24553 5254 2 870.445337 436.2296 Ataxin-1-like OS=Homo sapiens OX=9606 GN=ATXN1L PE=1 SV=1 4.53 1654 - 514378 - - - 0.7353 - 1.3 0.271 - 183 1 2 0 0.0006 8 0 0 0 2.23E+07 7.53E+07 - - - 1.8337 0.9147 221125_WJC_METTL3_EV_vs_WT_F03.05295.05295.2 6.81 16-Jul K.MLSC[160.03]AGADR[166.11].L "sp|P27635|RL10_HUMAN,sp|Q96L21|RL10L_HUMAN,tr|H7C123|H7C123_HUMAN,tr|H7C2C5|H7C2C5_HUMAN,tr|F8W7C6|F8W7C6_HUMAN,tr|A6QRI9|A6QRI9_HUMAN,tr|B8A6G2|B8A6G2_HUMAN,tr|X1WI28|X1WI28_HUMAN" 8 989.4298 0.97 24566 5295 2 989.42812 495.7222 60S ribosomal protein L10 OS=Homo sapiens OX=9606 GN=RPL10 PE=1 SV=4 5.59 1659.6 - 758284 - - - -1.704 - 1.207 0.015 - 137.5 2 2 0 -0.0017 9 0 0 0 1.31E+08 1.34E+08 - - - -0.4389 0.9695 221125_WJC_METTL3_EV_vs_WT_F03.05299.05299.2 0.428 12-Jun K.ALTNMSR.T "sp|Q9BY77|PDIP3_HUMAN,tr|F6VRR5|F6VRR5_HUMAN,tr|F8WCX5|F8WCX5_HUMAN" 3 791.396 1.41 24568 5299 2 791.392981 396.7053 Polymerase delta-interacting protein 3 OS=Homo sapiens OX=9606 GN=POLDIP3 PE=1 SV=2 9.79 1660.2 - 1.09E+07 - - - -3.7807 - 1.281 0.196 - 110 1 2 0 -0.003 7 0 0 0 1.67E+09 1.18E+09 - - - 1.2724 0.9678 221125_WJC_METTL3_EV_vs_WT_F03.05306.05306.2 11.8 14-Jun R.SPQQQPSR[166.11].L "sp|P13942|COBA2_HUMAN,tr|A0A140T9N1|A0A140T9N1_HUMAN,tr|A0A0C4DFS1|A0A0C4DFS1_HUMAN,tr|A2AAS7|A2AAS7_HUMAN,tr|A0A140T9X7|A0A140T9X7_HUMAN,tr|H0YIS1|H0YIS1_HUMAN,tr|A0A140T9N0|A0A140T9N0_HUMAN,tr|A0A140T9I7|A0A140T9I7_HUMAN,tr|A0A140TA54|A0A140TA54_HUMAN,tr|A0A140T9A1|A0A140T9A1_HUMAN,tr|A0A0G2JL35|A0A0G2JL35_HUMAN,tr|A0A0G2JI07|A0A0G2JI07_HUMAN,tr|A0A140T9W8|A0A140T9W8_HUMAN,tr|A0A140TA43|A0A140TA43_HUMAN,tr|Q4VXY6|Q4VXY6_HUMAN" 15 936.4653 1.34 24572 5306 2 936.46436 469.2399 Collagen alpha-2(XI) chain OS=Homo sapiens OX=9606 GN=COL11A2 PE=1 SV=5 9.47 1661 - 314835 - - - -0.9643 - 1.112 0.08 - 138.9 1 2 0 -0.0009 8 0 0 0 2.80E+07 2.09E+07 - - - -0.0482 0.9948 221125_WJC_METTL3_EV_vs_WT_F03.05311.05311.2 1 12-Aug R.LQEDEMR[166.11].R "sp|Q04323|UBXN1_HUMAN,tr|A0A087WTZ5|A0A087WTZ5_HUMAN,tr|E9PJ81|E9PJ81_HUMAN,tr|E9PRQ7|E9PRQ7_HUMAN" 4 929.4152 1.27 24574 5311 2 929.413372 465.7149 UBX domain-containing protein 1 OS=Homo sapiens OX=9606 GN=UBXN1 PE=1 SV=2 4.14 1661.6 - 400210 - - - -1.9679 - 1.56 0.159 - 226.1 1 2 0 -0.0018 7 0 0 0 6.71E+07 5.28E+07 - - - 1.6238 0.9948 221125_WJC_METTL3_EV_vs_WT_F03.05317.05317.2 0.134 16-Sep R.VLQTEQAVK[136.11].E "sp|Q9H7C9|AAMDC_HUMAN,tr|E9PNP3|E9PNP3_HUMAN,tr|E9PR47|E9PR47_HUMAN,tr|E9PIQ4|E9PIQ4_HUMAN" 4 1022.5852 1.75 24575 5317 2 1022.583416 512.2999 Mth938 domain-containing protein OS=Homo sapiens OX=9606 GN=AAMDC PE=1 SV=1 5.97 1662.5 - 2.12E+06 - - - -1.7055 - 1.466 0.181 - 200.6 1 2 0 -0.0017 9 0 0 0 1.99E+08 1.14E+08 - - - 1.484 0.9992 221125_WJC_METTL3_EV_vs_WT_F03.05340.05340.2 0.0116 12-Aug R.VINEEYK[136.11].L "sp|Q09028|RBBP4_HUMAN,sp|Q16576|RBBP7_HUMAN,tr|E9PIC4|E9PIC4_HUMAN,tr|E9PNS2|E9PNS2_HUMAN,tr|E9PNS6|E9PNS6_HUMAN,tr|C9JAJ9|C9JAJ9_HUMAN,tr|E9PC52|E9PC52_HUMAN" 7 901.4636 1.44 24583 5340 2 901.463488 451.7391 Histone-binding protein RBBP4 OS=Homo sapiens OX=9606 GN=RBBP4 PE=1 SV=3 4.53 1665.8 - 4.71E+06 - - - -0.1775 - 1.333 0.356 - 213.8 1 2 0 -0.0002 7 0 0 0 2.45E+09 1.69E+09 - - - 2.5811 0.9952 221125_WJC_METTL3_EV_vs_WT_F03.05344.05344.2 0.043 14-Jun R.VEAALDSR.K sp|Q9BYN8|RT26_HUMAN 1 859.4399 1.31 24585 5344 2 859.437765 430.7272 "28S ribosomal protein S26, mitochondrial OS=Homo sapiens OX=9606 GN=MRPS26 PE=1 SV=1" 4.37 1666.2 - 1.33E+06 - - - -2.5377 - 1.492 0.241 - 153.9 1 2 0 -0.0022 8 0 0 0 5.28E+08 4.04E+08 - - - 2.0271 0.9921 221125_WJC_METTL3_EV_vs_WT_F03.05347.05347.2 1.14 12-Jun K.EVATAIR[166.11].G "sp|P15880|RS2_HUMAN,tr|I3L404|I3L404_HUMAN,tr|E9PM36|E9PM36_HUMAN,tr|E9PPT0|E9PPT0_HUMAN,tr|E9PMM9|E9PMM9_HUMAN,tr|H0YEN5|H0YEN5_HUMAN" 6 768.4369 0.73 24586 5347 2 768.436357 385.2257 40S ribosomal protein S2 OS=Homo sapiens OX=9606 GN=RPS2 PE=1 SV=2 6.1 1666.6 - 1.78E+07 - - - -0.7366 - 1.265 0.142 - 256.4 1 2 0 -0.0006 7 0 0 0 5.91E+08 8.06E+08 - - - 0.8345 0.9975 221125_WJC_METTL3_EV_vs_WT_F03.05352.05352.2 0.253 12-Jul R.VINEEYK.L "sp|Q09028|RBBP4_HUMAN,sp|Q16576|RBBP7_HUMAN,tr|E9PIC4|E9PIC4_HUMAN,tr|E9PNS2|E9PNS2_HUMAN,tr|E9PNS6|E9PNS6_HUMAN,tr|C9JAJ9|C9JAJ9_HUMAN,tr|E9PC52|E9PC52_HUMAN" 7 893.4494 1.44 24588 5352 2 893.448533 447.732 Histone-binding protein RBBP4 OS=Homo sapiens OX=9606 GN=RBBP4 PE=1 SV=3 4.53 1667.2 - 1.62E+07 - - - -1.0241 - 1.344 0.242 - 179.7 1 2 0 -0.0009 7 0 0 0 2.45E+09 1.69E+09 - - - 1.7649 0.9641 221125_WJC_METTL3_EV_vs_WT_F03.05361.05361.2 2.16 14-Jun R.VVQQEVVR.Y "sp|O60437|PEPL_HUMAN,tr|K7EKI8|K7EKI8_HUMAN,tr|K7EQ71|K7EQ71_HUMAN" 3 955.5451 1.58 24592 5361 2 955.543683 478.7798 Periplakin OS=Homo sapiens OX=9606 GN=PPL PE=1 SV=4 5.97 1668.4 - 246431 - - - -1.462 - 1.124 0.106 - 101.3 2 2 0 -0.0014 8 0 0 0 7.51E+06 4.75E+06 - - - 0.0416 0.9979 221125_WJC_METTL3_EV_vs_WT_F03.05383.05383.2 0.012 12-Jun K.FIDTTSK.F "sp|Q92901|RL3L_HUMAN,sp|P39023|RL3_HUMAN,tr|G5E9G0|G5E9G0_HUMAN" 3 810.4123 0.86 24599 5383 2 810.410801 406.2134 60S ribosomal protein L3-like OS=Homo sapiens OX=9606 GN=RPL3L PE=2 SV=3 5.84 1671.5 - 5.86E+06 - - - -1.8916 - 1.341 0.318 - 100.6 1 2 0 -0.0015 7 0 0 0 5.53E+08 6.43E+08 - - - 2.319 0.9994 221125_WJC_METTL3_EV_vs_WT_F03.05386.05386.2 0.0367 14-Aug K.LTQGETLR[166.11].K "sp|Q15392|DHC24_HUMAN,tr|A0A0A0MTI1|A0A0A0MTI1_HUMAN" 2 926.5061 3.07 24602 5386 2 926.504758 464.2603 Delta(24)-sterol reductase OS=Homo sapiens OX=9606 GN=DHCR24 PE=1 SV=2 6 1671.7 - 855623 - - - -1.4107 - 1.652 0.367 - 262.7 1 2 0 -0.0013 8 0 0 0 8.53E+07 2.78E+07 - - - 3.2652 0.999 221125_WJC_METTL3_EV_vs_WT_F03.05388.05388.2 0.0302 14-Sep K.LTQGETLR.K "sp|Q15392|DHC24_HUMAN,tr|A0A0A0MTI1|A0A0A0MTI1_HUMAN" 2 916.4978 3.07 24603 5388 2 916.495468 459.2562 Delta(24)-sterol reductase OS=Homo sapiens OX=9606 GN=DHCR24 PE=1 SV=2 6 1671.9 - 1.47E+06 - - - -2.539 - 1.972 0.325 - 353.9 1 2 0 -0.0023 8 0 0 0 8.62E+07 2.81E+07 - - - 3.4887 0.9999 221125_WJC_METTL3_EV_vs_WT_F03.05423.05423.2 0.000397 12-Aug K.C[160.03]GVISPR[166.11].F "sp|P62244|RS15A_HUMAN,tr|I3L3P7|I3L3P7_HUMAN,tr|H3BVC7|H3BVC7_HUMAN" 3 797.4093 0.99 24612 5423 2 797.409041 399.7119 40S ribosomal protein S15a OS=Homo sapiens OX=9606 GN=RPS15A PE=1 SV=2 8.25 1677 - 5.82E+06 - - - -0.3599 - 1.844 0.496 - 397.9 1 2 0 -0.0003 7 0 0 0 1.38E+09 1.39E+09 - - - 4.6433 0.9936 221125_WJC_METTL3_EV_vs_WT_F03.05444.05444.2 0.199 14-Aug R.LTSSLTTK.G "sp|P22695|QCR2_HUMAN,tr|H3BP04|H3BP04_HUMAN,tr|H3BUE4|H3BUE4_HUMAN,tr|H3BUI9|H3BUI9_HUMAN,tr|H3BRG4|H3BRG4_HUMAN,tr|H3BSJ9|H3BSJ9_HUMAN,tr|A0A087WVZ4|A0A087WVZ4_HUMAN" 7 849.4807 1.4 24620 5444 2 849.480531 425.7477 "Cytochrome b-c1 complex subunit 2, mitochondrial OS=Homo sapiens OX=9606 GN=UQCRC2 PE=1 SV=3" 8.75 1679.8 - 1.75E+06 - - - -0.2555 - 1.251 0.163 - 135.7 1 2 0 -0.0002 8 0 0 0 1.22E+08 8.74E+07 - - - 0.9203 0.9991 221125_WJC_METTL3_EV_vs_WT_F03.05448.05448.2 0.144 14-Aug K.LLESEESR.M "sp|Q5XKE5|K2C79_HUMAN,tr|H0YID6|H0YID6_HUMAN" 2 961.4716 461.19 24622 5448 2 961.471547 481.7431 "Keratin, type II cytoskeletal 79 OS=Homo sapiens OX=9606 GN=KRT79 PE=1 SV=2" 4.25 1680.4 - 370869 - - - -0.0967 - 1.494 0.295 - 138.6 1 2 0 -0.0001 8 0 0 0 1.43E+07 3.11E+04 - - - 2.4306 0.9586 221125_WJC_METTL3_EV_vs_WT_F03.05464.05464.2 5.77 14-Jul R.VPSLATSK[136.11].V sp|P0CW27|CC166_HUMAN 1 809.4738 1.63 24625 5464 2 809.472886 405.7442 Coiled-coil domain-containing protein 166 OS=Homo sapiens OX=9606 GN=CCDC166 PE=4 SV=1 8.72 1682.9 - 1.14E+06 - - - -1.1526 - 1.188 0.038 - 99.6 1 2 0 -0.0009 8 0 0 0 8.69E+07 5.34E+07 - - - -0.1591 0.9962 221125_WJC_METTL3_EV_vs_WT_F03.05469.05469.2 0.506 14-Jul K.ALETVQER.K "sp|Q96QA5|GSDMA_HUMAN,tr|J3KRG2|J3KRG2_HUMAN" 2 944.4927 13.41 24627 5469 2 944.493416 473.2536 Gasdermin-A OS=Homo sapiens OX=9606 GN=GSDMA PE=1 SV=4 4.53 1683.6 - 934953 - - - 0.7475 - 1.378 0.193 - 168 1 2 0 0.0007 8 0 0 0 5.39E+07 4.02E+06 - - - 1.4333 0.9984 221125_WJC_METTL3_EV_vs_WT_F03.05472.05472.2 0.0365 14-Jul K.ILPTSETK[136.11].Q "sp|P18583|SON_HUMAN,tr|H7C1M2|H7C1M2_HUMAN" 2 895.5106 2.67 24629 5472 2 895.510522 448.7626 Protein SON OS=Homo sapiens OX=9606 GN=SON PE=1 SV=4 6 1683.9 - 486966 - - - -0.0849 - 1.259 0.303 - 137.6 1 2 0 -0.0001 8 0 0 0 3.14E+08 1.18E+08 - - - 1.9736 0.9997 221125_WJC_METTL3_EV_vs_WT_F03.05484.05484.2 0.0126 16-Nov R.TGVVTDGVK.H "sp|P38117|ETFB_HUMAN,tr|M0QY67|M0QY67_HUMAN" 2 874.476 1.43 24633 5484 2 874.475684 438.2453 Electron transfer flavoprotein subunit beta OS=Homo sapiens OX=9606 GN=ETFB PE=1 SV=3 5.5 1685.7 - 6.70E+06 - - - -0.3579 - 2.039 0.32 - 444.8 1 2 0 -0.0003 9 0 0 0 2.50E+08 1.75E+08 - - - 3.4656 0.9399 221125_WJC_METTL3_EV_vs_WT_F03.05485.05485.2 2.45 12-Jul R.ITDDQLK.L "sp|Q86UP3|ZFHX4_HUMAN,tr|E7EVZ1|E7EVZ1_HUMAN" 2 831.4338 1.17 24634 5485 2 831.435106 416.7242 Zinc finger homeobox protein 4 OS=Homo sapiens OX=9606 GN=ZFHX4 PE=1 SV=1 4.21 1685.8 - 1.26E+06 - - - 1.5732 - 1.091 0.066 - 107.1 1 2 0 0.0013 7 0 0 0 4.63E+07 3.96E+07 - - - -0.196 0.9942 221125_WJC_METTL3_EV_vs_WT_F03.05489.05489.2 0.138 14-Jun R.SLEPGTPR[166.11].W "sp|P51570|GALK1_HUMAN,tr|K7ERJ9|K7ERJ9_HUMAN,tr|K7ERN9|K7ERN9_HUMAN,tr|K7EII7|K7EII7_HUMAN" 4 865.4533 3.19 24636 5489 2 865.452464 433.7339 Galactokinase OS=Homo sapiens OX=9606 GN=GALK1 PE=1 SV=1 5.72 1686.2 - 1.66E+06 - - - -0.9671 - 1.197 0.208 - 135.5 1 2 0 -0.0008 8 0 0 0 2.77E+08 8.69E+07 - - - 1.1193 0.9964 221125_WJC_METTL3_EV_vs_WT_F03.05492.05492.2 0.0221 14-Jul R.VPC[160.03]TPVAR[166.11].L sp|P61962|DCAF7_HUMAN 1 908.4777 1.2 24637 5492 2 908.477157 455.2461 DDB1- and CUL4-associated factor 7 OS=Homo sapiens OX=9606 GN=DCAF7 PE=1 SV=1 8.22 1686.7 - 353118 - - - -0.6439 - 1.261 0.223 - 114.2 1 2 0 -0.0006 8 0 0 0 2.90E+08 2.42E+08 - - - 1.3873 0.9911 221125_WJC_METTL3_EV_vs_WT_F03.05505.05505.2 0.626 12-Jun K.TGIYEEK[136.11].H "sp|P27824|CALX_HUMAN,tr|A0A7P0T937|A0A7P0T937_HUMAN,tr|A0A7P0T840|A0A7P0T840_HUMAN,tr|D6RFL1|D6RFL1_HUMAN,tr|A0A7P0Z4H2|A0A7P0Z4H2_HUMAN,tr|A0A7P0TB65|A0A7P0TB65_HUMAN,tr|A0A7P0TAE9|A0A7P0TAE9_HUMAN,tr|D6RGY2|D6RGY2_HUMAN,tr|A0A7P0T8G1|A0A7P0T8G1_HUMAN,tr|A0A7P0Z4D6|A0A7P0Z4D6_HUMAN,tr|A0A7P0Z484|A0A7P0Z484_HUMAN,tr|A0A7P0TAR9|A0A7P0TAR9_HUMAN,tr|A0A7P0T9L0|A0A7P0T9L0_HUMAN" 13 846.4214 1.2 24641 5505 2 846.421286 424.218 Calnexin OS=Homo sapiens OX=9606 GN=CANX PE=1 SV=2 4.53 1688.5 - 3.78E+06 - - - -0.1926 - 1.217 0.14 - 119.3 1 2 0 -0.0002 7 0 0 0 9.75E+08 8.11E+08 - - - 0.6973 0.9997 221125_WJC_METTL3_EV_vs_WT_F03.05513.05513.2 0.00013 14-Aug R.MGANNLER[166.11].M "sp|P52272|HNRPM_HUMAN,tr|M0R2I7|M0R2I7_HUMAN,tr|A0A087X0X3|A0A087X0X3_HUMAN,tr|M0QZM1|M0QZM1_HUMAN" 4 913.4315 1.61 24645 5513 2 913.431019 457.723 Heterogeneous nuclear ribonucleoprotein M OS=Homo sapiens OX=9606 GN=HNRNPM PE=1 SV=3 5.75 1689.5 - 686795 - - - -0.5485 - 1.798 0.369 - 207.2 1 2 0 -0.0005 8 0 0 0 1.06E+09 6.55E+08 - - - 3.5357 0.8322 221125_WJC_METTL3_EV_vs_WT_F03.05514.05514.2 0.26 20-Apr K.IGSGFFSEVFK.V "sp|Q96S53|TESK2_HUMAN,tr|A0A5F9ZGZ0|A0A5F9ZGZ0_HUMAN" 2 1216.6128 1.95 24646 5514 2 1216.606058 609.3137 Dual specificity testis-specific protein kinase 2 OS=Homo sapiens OX=9606 GN=TESK2 PE=1 SV=1 6 1689.6 - 195104 - - - -5.5622 - 0.961 0.291 - 43.6 3 2 0 -0.0068 11 0 0 0 1.17E+07 5.99E+06 - - - 0.8675 0.9997 221125_WJC_METTL3_EV_vs_WT_F03.05515.05515.2 0.000179 14-Sep R.MGANNLER.M "sp|P52272|HNRPM_HUMAN,tr|M0R2I7|M0R2I7_HUMAN,tr|A0A087X0X3|A0A087X0X3_HUMAN,tr|M0QZM1|M0QZM1_HUMAN" 4 903.4233 1.61 24647 5515 2 903.42256 452.7189 Heterogeneous nuclear ribonucleoprotein M OS=Homo sapiens OX=9606 GN=HNRNPM PE=1 SV=3 5.75 1689.7 - 841926 - - - -0.7638 - 1.786 0.406 - 339 1 2 0 -0.0007 8 0 0 0 1.06E+09 6.55E+08 - - - 3.7887 0.9991 221125_WJC_METTL3_EV_vs_WT_F03.05523.05523.2 0.0314 14-Aug R.VPC[160.03]TPVAR.L sp|P61962|DCAF7_HUMAN 1 898.4695 1.19 24651 5523 2 898.469437 450.242 DDB1- and CUL4-associated factor 7 OS=Homo sapiens OX=9606 GN=DCAF7 PE=1 SV=1 8.22 1690.6 - 2.70E+06 - - - -0.039 - 1.381 0.326 - 265.6 1 2 0 0 8 0 0 0 2.97E+08 2.48E+08 - - - 2.4224 0.9977 221125_WJC_METTL3_EV_vs_WT_F03.05531.05531.2 0.0582 12-Jul R.YGEQGLR.E sp|O60884|DNJA2_HUMAN 1 821.4032 0.49 24655 5531 2 821.403867 411.7089 DnaJ homolog subfamily A member 2 OS=Homo sapiens OX=9606 GN=DNAJA2 PE=1 SV=1 6 1691.6 - 1.13E+06 - - - 0.8534 - 1.257 0.28 - 118.9 1 2 0 0.0007 7 0 0 0 3.96E+08 8.09E+08 - - - 1.8336 0.9986 221125_WJC_METTL3_EV_vs_WT_F03.05534.05534.2 0.00448 14-Jul K.VPLAGEGR[166.11].K "sp|Q9BYD2|RM09_HUMAN,tr|A0A1W2PPK1|A0A1W2PPK1_HUMAN,tr|A0A1W2PRK9|A0A1W2PRK9_HUMAN,tr|Q5SZR1|Q5SZR1_HUMAN,tr|A0A1W2PS92|A0A1W2PS92_HUMAN,tr|A0A1W2PQB6|A0A1W2PQB6_HUMAN" 6 807.4478 2.84 24656 5534 2 807.449112 404.7312 "39S ribosomal protein L9, mitochondrial OS=Homo sapiens OX=9606 GN=MRPL9 PE=1 SV=2" 5.97 1692 - 869021 - - - 1.5976 - 1.38 0.352 - 166.2 1 2 0 0.0013 8 0 0 0 2.07E+08 7.28E+07 - - - 2.6119 0.9948 221125_WJC_METTL3_EV_vs_WT_F03.05544.05544.2 0.557 12-Jul R.LEGELTK.V "sp|Q15020|SART3_HUMAN,tr|A0A494C0L2|A0A494C0L2_HUMAN,tr|F8W667|F8W667_HUMAN,tr|A0A499FI31|A0A499FI31_HUMAN" 4 788.428 0.98 24657 5544 2 788.428012 395.2213 Squamous cell carcinoma antigen recognized by T-cells 3 OS=Homo sapiens OX=9606 GN=SART3 PE=1 SV=1 4.53 1693.6 - 6.49E+06 - - - 0.0355 - 1.243 0.182 - 127.2 1 2 0 0 7 0 0 0 3.81E+08 3.88E+08 - - - 1.0745 0.9581 221125_WJC_METTL3_EV_vs_WT_F03.05546.05546.2 1.93 12-Jun K.NPADLPK[136.11].L sp|P13639|EF2_HUMAN 1 761.4163 0.001 24659 5546 2 761.418608 381.7154 Elongation factor 2 OS=Homo sapiens OX=9606 GN=EEF2 PE=1 SV=4 5.84 1693.8 - 8.78E+06 - - - 3.0259 - 1.108 0.177 - 157.6 1 2 0 0.0023 7 0 0 0 0.00E+00 6.08E+08 - - - 0.6726 0.9961 221125_WJC_METTL3_EV_vs_WT_F03.05547.05547.2 0.0575 16-Jun K.DVDSAYMNK.V sp|P12035|K2C3_HUMAN 1 1041.4437 999 24660 5547 2 1041.445107 521.7291 "Keratin, type II cytoskeletal 3 OS=Homo sapiens OX=9606 GN=KRT3 PE=1 SV=3" 4.21 1693.9 - 175168 - - - 1.3404 - 1.014 0.344 - 74.9 1 2 0 0.0014 9 0 0 0 3.78E+08 0.00E+00 - - - 1.6216 0.9195 221125_WJC_METTL3_EV_vs_WT_F03.05553.05553.2 2.42 14-Jun K.VPLAGEGR.K "sp|Q9BYD2|RM09_HUMAN,tr|A0A1W2PPK1|A0A1W2PPK1_HUMAN,tr|A0A1W2PRK9|A0A1W2PRK9_HUMAN,tr|Q5SZR1|Q5SZR1_HUMAN,tr|A0A1W2PS92|A0A1W2PS92_HUMAN,tr|A0A1W2PQB6|A0A1W2PQB6_HUMAN" 6 797.4396 1.81 24661 5553 2 797.44224 399.7271 "39S ribosomal protein L9, mitochondrial OS=Homo sapiens OX=9606 GN=MRPL9 PE=1 SV=2" 5.97 1694.9 - 3.63E+06 - - - 3.3708 - 1.04 0.165 - 107.8 1 2 0 0.0027 8 0 0 0 1.19E+08 6.55E+07 - - - 0.3771 0.9962 221125_WJC_METTL3_EV_vs_WT_F03.05555.05555.2 0.196 14-Jun R.LLEEEDSK[136.11].L "sp|Q96CT7|CC124_HUMAN,tr|M0R2F5|M0R2F5_HUMAN" 2 969.4746 0.93 24662 5555 2 969.475929 485.7446 Coiled-coil domain-containing protein 124 OS=Homo sapiens OX=9606 GN=CCDC124 PE=1 SV=1 4 1695.1 - 270421 - - - 1.3636 - 1.206 0.276 - 100.9 1 2 0 0.0013 8 0 0 0 2.11E+08 2.27E+08 - - - 1.644 0.9994 221125_WJC_METTL3_EV_vs_WT_F03.05557.05557.2 0.0249 12-Aug R.YGEQGLR[166.11].E sp|O60884|DNJA2_HUMAN 1 831.4114 0.49 24663 5557 2 831.411505 416.713 DnaJ homolog subfamily A member 2 OS=Homo sapiens OX=9606 GN=DNAJA2 PE=1 SV=1 6 1695.3 - 1.97E+07 - - - 0.083 - 1.555 0.316 - 191.9 1 2 0 0.0001 7 0 0 0 3.97E+08 8.09E+08 - - - 2.7738 0.9954 221125_WJC_METTL3_EV_vs_WT_F03.05561.05561.2 0.1 12-Jun R.GPMLDQR.G "sp|P33240|CSTF2_HUMAN,sp|Q9H0L4|CSTFT_HUMAN,tr|E9PID8|E9PID8_HUMAN,tr|E7EWR4|E7EWR4_HUMAN" 4 815.396 2.1 24665 5561 2 815.394166 408.7053 Cleavage stimulation factor subunit 2 OS=Homo sapiens OX=9606 GN=CSTF2 PE=1 SV=1 5.84 1695.8 - 553970 - - - -2.2161 - 1.333 0.259 - 185.9 1 2 0 -0.0018 7 0 0 0 4.57E+07 2.18E+07 - - - 1.8642 0.8368 221125_WJC_METTL3_EV_vs_WT_F03.05566.05566.2 2.71 12-Jun K.VLYC[160.03]QAK.D "sp|O75147|OBSL1_HUMAN,tr|A6NN50|A6NN50_HUMAN" 2 880.4477 0.48 24668 5566 2 880.448169 441.2311 Obscurin-like protein 1 OS=Homo sapiens OX=9606 GN=OBSL1 PE=1 SV=4 8.17 1696.3 - 214532 - - - 0.5622 - 0.899 0.016 - 150.3 1 2 0 0.0005 7 0 0 0 1.26E+07 2.62E+07 - - - -1.1783 0.9692 221125_WJC_METTL3_EV_vs_WT_F03.05577.05577.2 6.96 12-Jun K.NADELVK[136.11].Q "sp|P17987|TCPA_HUMAN,tr|F5H726|F5H726_HUMAN,tr|F5H136|F5H136_HUMAN,tr|E7ERF2|E7ERF2_HUMAN,tr|F5H676|F5H676_HUMAN" 5 795.4218 0.51 24671 5577 2 795.421403 398.7182 T-complex protein 1 subunit alpha OS=Homo sapiens OX=9606 GN=TCP1 PE=1 SV=1 4.37 1697.9 - 4.38E+06 - - - -0.4777 - 1.169 0.048 - 156.5 1 2 0 -0.0004 7 0 0 0 1.75E+09 3.45E+09 - - - -0.1098 1 221125_WJC_METTL3_EV_vs_WT_F03.05579.05579.2 1.81E-06 22-Dec K.VGGTSDVEVNEK.K "sp|P10809|CH60_HUMAN,tr|A0A7I2V2X6|A0A7I2V2X6_HUMAN,tr|A0A7I2YQK6|A0A7I2YQK6_HUMAN,tr|A0A7I2V599|A0A7I2V599_HUMAN" 4 1232.5885 1.16 24672 5579 2 1232.588358 617.3015 "60 kDa heat shock protein, mitochondrial OS=Homo sapiens OX=9606 GN=HSPD1 PE=1 SV=2" 4.14 1698.1 - 442455 - - - -0.0836 - 2.649 0.581 - 440.6 1 2 0 -0.0001 12 0 0 0 2.20E+07 1.91E+07 - - - 5.8955 0.8541 221125_WJC_METTL3_EV_vs_WT_F03.05582.05582.2 3.78 14-Jul K.TIESETVR[166.11].T "sp|O43615|TIM44_HUMAN,tr|M0R301|M0R301_HUMAN,tr|M0QXU7|M0QXU7_HUMAN" 3 943.485 1.15 24673 5582 2 943.48269 472.7498 Mitochondrial import inner membrane translocase subunit TIM44 OS=Homo sapiens OX=9606 GN=TIMM44 PE=1 SV=2 4.53 1698.5 - 502395 - - - -2.4431 - 1.112 0.02 - 110.5 1 2 0 -0.0023 8 0 0 0 1.42E+08 1.24E+08 - - - -0.4918 0.9999 221125_WJC_METTL3_EV_vs_WT_F03.05583.05583.2 1.09E-06 22-Nov K.VGGTSDVEVNEK[136.11].K "sp|P10809|CH60_HUMAN,tr|A0A7I2V2X6|A0A7I2V2X6_HUMAN,tr|A0A7I2YQK6|A0A7I2YQK6_HUMAN,tr|A0A7I2V599|A0A7I2V599_HUMAN" 4 1240.6027 1.15 24674 5583 2 1240.601876 621.3086 "60 kDa heat shock protein, mitochondrial OS=Homo sapiens OX=9606 GN=HSPD1 PE=1 SV=2" 4.14 1698.6 - 340376 - - - -0.6328 - 2.393 0.546 - 405.5 1 2 0 -0.0008 12 0 0 0 2.22E+07 1.93E+07 - - - 5.3693 0.9966 221125_WJC_METTL3_EV_vs_WT_F03.05585.05585.2 0.309 14-Jul K.TIESETVR.T "sp|O43615|TIM44_HUMAN,tr|M0R301|M0R301_HUMAN,tr|M0QXU7|M0QXU7_HUMAN" 3 933.4767 1.15 24676 5585 2 933.477429 467.7456 Mitochondrial import inner membrane translocase subunit TIM44 OS=Homo sapiens OX=9606 GN=TIMM44 PE=1 SV=2 4.53 1698.9 - 466474 - - - 0.7542 - 1.187 0.284 - 140.6 2 2 0 0.0007 8 0 0 0 1.42E+08 1.24E+08 - - - 1.521 0.9984 221125_WJC_METTL3_EV_vs_WT_F03.05588.05588.2 0.0344 12-Jul R.VVDQPLK[136.11].L "sp|Q6P1J9|CDC73_HUMAN,tr|A0A1B0GUB2|A0A1B0GUB2_HUMAN,tr|A0A3B3IRP5|A0A3B3IRP5_HUMAN" 3 805.4789 1.05 24677 5588 2 805.478254 403.7467 Parafibromin OS=Homo sapiens OX=9606 GN=CDC73 PE=1 SV=1 5.81 1699.3 - 2.33E+06 - - - -0.807 - 1.288 0.297 - 157.2 1 2 0 -0.0006 7 0 0 0 1.61E+08 1.53E+08 - - - 2.0364 0.9953 221125_WJC_METTL3_EV_vs_WT_F03.05600.05600.2 0.0431 14-Aug K.EVTAIETK.L "sp|Q14683|SMC1A_HUMAN,tr|G8JLG1|G8JLG1_HUMAN,tr|A0A6Q8PHC3|A0A6Q8PHC3_HUMAN,tr|V9GY57|V9GY57_HUMAN" 4 889.4757 1.9 24683 5600 2 889.47725 445.7451 Structural maintenance of chromosomes protein 1A OS=Homo sapiens OX=9606 GN=SMC1A PE=1 SV=2 4.53 1700.8 - 1.23E+06 - - - 1.7842 - 1.558 0.175 - 147.4 1 2 0 0.0016 8 0 0 0 7.09E+07 3.74E+07 - - - 1.6703 0.9869 221125_WJC_METTL3_EV_vs_WT_F03.05609.05609.2 0.0346 14-Jun K.VYVTAESR.F sp|P42684|ABL2_HUMAN 1 923.4712 0.06 24688 5609 2 923.475665 462.7429 Tyrosine-protein kinase ABL2 OS=Homo sapiens OX=9606 GN=ABL2 PE=1 SV=1 5.97 1701.8 - 160382 - - - 4.7852 - 1.531 0.307 - 154.6 1 2 0 0.0044 8 0 0 0 8.38E+06 1.38E+08 - - - 2.5917 0.9939 221125_WJC_METTL3_EV_vs_WT_F03.05618.05618.2 0.168 12-Aug K.NADELVK.Q "sp|P17987|TCPA_HUMAN,tr|F5H726|F5H726_HUMAN,tr|F5H136|F5H136_HUMAN,tr|E7ERF2|E7ERF2_HUMAN,tr|F5H676|F5H676_HUMAN" 5 787.4076 0.5 24690 5618 2 787.406829 394.7111 T-complex protein 1 subunit alpha OS=Homo sapiens OX=9606 GN=TCP1 PE=1 SV=1 4.37 1703.2 - 3.08E+07 - - - -0.9576 - 1.54 0.091 - 341.7 1 2 0 -0.0008 7 0 0 0 1.74E+09 3.46E+09 - - - 1.081 0.8285 221125_WJC_METTL3_EV_vs_WT_F03.05619.05619.2 0.526 14-Jun R.C[160.03]LDGQPMK[136.11].C "sp|Q9BY77|PDIP3_HUMAN,tr|F6VRR5|F6VRR5_HUMAN" 2 955.4347 1.35 24691 5619 2 955.433245 478.7246 Polymerase delta-interacting protein 3 OS=Homo sapiens OX=9606 GN=POLDIP3 PE=1 SV=2 5.83 1703.3 - 498944 - - - -1.4946 - 1.018 0.004 - 128.6 2 2 0 -0.0014 8 0 0 0 8.73E+08 6.45E+08 - - - -1.0106 0.8856 221125_WJC_METTL3_EV_vs_WT_F03.05632.05632.2 6.65 16-Jun K.IVANPEDTR[166.11].S sp|P82914|RT15_HUMAN 1 1023.5224 1.02 24696 5632 2 1023.520245 512.7685 "28S ribosomal protein S15, mitochondrial OS=Homo sapiens OX=9606 GN=MRPS15 PE=1 SV=1" 4.37 1704.9 - 387518 - - - -2.1485 - 1.023 0.06 - 63.6 1 2 0 -0.0022 9 0 0 0 2.28E+07 2.24E+07 - - - -0.4507 0.9925 221125_WJC_METTL3_EV_vs_WT_F03.05637.05637.2 0.0593 14-Jul K.VMPAPPPK.E "sp|P23588|IF4B_HUMAN,tr|E7EX17|E7EX17_HUMAN" 2 835.4626 1.14 24698 5637 2 835.459878 418.7386 Eukaryotic translation initiation factor 4B OS=Homo sapiens OX=9606 GN=EIF4B PE=1 SV=2 8.72 1705.5 - 2.45E+06 - - - -3.2533 - 1.447 0.261 - 205.2 1 2 0 -0.0027 8 0 0 0 2.13E+08 1.88E+08 - - - 2.0823 0.9674 221125_WJC_METTL3_EV_vs_WT_F03.05642.05642.2 0.805 14-May K.VMPAPPPK[136.11].E "sp|P23588|IF4B_HUMAN,tr|E7EX17|E7EX17_HUMAN" 2 843.4768 2.91 24700 5642 2 843.477449 422.7457 Eukaryotic translation initiation factor 4B OS=Homo sapiens OX=9606 GN=EIF4B PE=1 SV=2 8.72 1706.1 - 697925 - - - 0.7742 - 1.107 0.155 - 54.1 16 2 0 0.0007 8 0 0 0 1.55E+08 5.33E+07 - - - -0.0457 0.9993 221125_WJC_METTL3_EV_vs_WT_F03.05645.05645.2 0.0175 14-Nov R.C[160.03]LDGQPMK.C "sp|Q9BY77|PDIP3_HUMAN,tr|F6VRR5|F6VRR5_HUMAN" 2 947.4205 1.35 24701 5645 2 947.418842 474.7175 Polymerase delta-interacting protein 3 OS=Homo sapiens OX=9606 GN=POLDIP3 PE=1 SV=2 5.83 1706.5 - 2.60E+06 - - - -1.7215 - 1.805 0.335 - 418 1 2 0 -0.0016 8 0 0 0 8.73E+08 6.45E+08 - - - 3.2959 0.9993 221125_WJC_METTL3_EV_vs_WT_F03.05653.05653.2 0.063 14-Aug K.LLEGEESR.L "sp|P08670|VIME_HUMAN,sp|Q9NSB2|KRT84_HUMAN,sp|P17661|DESM_HUMAN,sp|P05787|K2C8_HUMAN,sp|P41219|PERI_HUMAN,sp|Q7Z794|K2C1B_HUMAN,sp|P04264|K2C1_HUMAN,sp|P08729|K2C7_HUMAN,tr|H7C5W5|H7C5W5_HUMAN,tr|B0YJC5|B0YJC5_HUMAN,tr|B0YJC4|B0YJC4_HUMAN" 11 931.4611 1.94 24704 5653 2 931.459106 466.7378 Vimentin OS=Homo sapiens OX=9606 GN=VIM PE=1 SV=4 4.25 1707.5 - 3.01E+06 - - - -2.1139 - 1.746 0.383 - 171.4 1 2 0 -0.002 8 0 0 0 1.01E+10 5.23E+09 - - - 3.5501 0.9982 221125_WJC_METTL3_EV_vs_WT_F03.05654.05654.2 0.0227 14-Jul K.LLEGEESR[166.11].L "sp|P08670|VIME_HUMAN,sp|Q9NSB2|KRT84_HUMAN,sp|P17661|DESM_HUMAN,sp|P05787|K2C8_HUMAN,sp|P41219|PERI_HUMAN,sp|Q7Z794|K2C1B_HUMAN,sp|P04264|K2C1_HUMAN,sp|P08729|K2C7_HUMAN,tr|H7C5W5|H7C5W5_HUMAN,tr|B0YJC5|B0YJC5_HUMAN,tr|B0YJC4|B0YJC4_HUMAN" 11 941.4693 1.94 24705 5654 2 941.466482 471.7419 Vimentin OS=Homo sapiens OX=9606 GN=VIM PE=1 SV=4 4.25 1707.6 - 2.00E+06 - - - -3.041 - 1.614 0.381 - 158.5 1 2 0 -0.0029 8 0 0 0 1.01E+10 5.23E+09 - - - 3.298 0.9843 221125_WJC_METTL3_EV_vs_WT_F03.05692.05692.2 0.45 14-May R.SMMSSYER[166.11].S "sp|P18583|SON_HUMAN,tr|H7C1M2|H7C1M2_HUMAN" 2 999.4029 1.41 24714 5692 2 999.401361 500.7087 Protein SON OS=Homo sapiens OX=9606 GN=SON PE=1 SV=4 5.72 1713.2 - 302832 - - - -1.5619 - 0.8 0.307 - 85.5 1 2 0 -0.0016 8 0 0 0 1.20E+07 8.51E+06 - - - 0.635 0.9986 221125_WJC_METTL3_EV_vs_WT_F03.05696.05696.2 0.18 12-Aug K.LNELGQR.L "sp|Q8IWZ3|ANKH1_HUMAN,tr|E9PDP5|E9PDP5_HUMAN" 2 828.4454 1.11 24715 5696 2 828.443532 415.23 Ankyrin repeat and KH domain-containing protein 1 OS=Homo sapiens OX=9606 GN=ANKHD1 PE=1 SV=1 6 1713.7 - 4.17E+06 - - - -2.2138 - 1.85 0.262 - 222.8 1 2 0 -0.0018 7 0 0 0 1.67E+08 1.51E+08 - - - 2.9248 0.8619 221125_WJC_METTL3_EV_vs_WT_F03.05699.05699.2 1.34 12-Jun K.VINVGQR.F sp|O60825|F262_HUMAN 1 784.4555 2.22 24716 5699 2 784.453454 393.235 "6-phosphofructo-2-kinase\fructose-2,6-bisphosphatase 2 OS=Homo sapiens OX=9606 GN=PFKFB2 PE=1 SV=2" 9.72 1714.1 - 5.33E+06 - - - -2.6541 - 1.207 0.001 - 112.4 1 2 0 -0.0021 7 0 0 0 2.43E+08 1.09E+08 - - - -0.3561 0.9609 221125_WJC_METTL3_EV_vs_WT_F03.05707.05707.2 1.9 12-Jun R.VDIAEGR.K "sp|Q15056|IF4H_HUMAN,tr|A0A7I2V4E4|A0A7I2V4E4_HUMAN,tr|A0A7I2V385|A0A7I2V385_HUMAN" 3 758.3923 0.75 24719 5707 2 758.391165 380.2034 Eukaryotic translation initiation factor 4H OS=Homo sapiens OX=9606 GN=EIF4H PE=1 SV=5 4.37 1715.1 - 1.27E+06 - - - -1.4531 - 1.27 0.076 - 85.6 7 2 0 -0.0011 7 0 0 0 1.65E+08 2.19E+08 - - - -0.0182 0.9946 221125_WJC_METTL3_EV_vs_WT_F03.05716.05716.2 0.387 12-Jul R.VPEEDLK[136.11].R sp|Q99832|TCPH_HUMAN 1 836.4371 0.26 24723 5716 2 836.43567 419.2258 T-complex protein 1 subunit eta OS=Homo sapiens OX=9606 GN=CCT7 PE=1 SV=2 4.14 1716.2 - 1.26E+07 - - - -1.7084 - 1.429 0.175 - 183.9 1 2 0 -0.0014 7 0 0 0 3.19E+08 1.21E+09 - - - 1.4642 0.977 221125_WJC_METTL3_EV_vs_WT_F03.05718.05718.2 0.132 14-Jul R.LLEGEEQR.L "sp|Q14533|KRT81_HUMAN,sp|O43790|KRT86_HUMAN,sp|P78385|KRT83_HUMAN,tr|A0A087X106|A0A087X106_HUMAN" 4 972.4876 0.48 24725 5718 2 972.482528 487.2511 "Keratin, type II cuticular Hb1 OS=Homo sapiens OX=9606 GN=KRT81 PE=1 SV=3" 4.25 1716.4 - 1.07E+06 - - - -5.2402 - 1.489 0.285 - 150.8 1 2 0 -0.0051 8 0 0 0 6.47E+07 1.35E+08 - - - 2.3451 0.8688 221125_WJC_METTL3_EV_vs_WT_F03.05722.05722.2 0.526 14-Jun K.VSPLASDR.R sp|Q8WUF5|IASPP_HUMAN 1 843.445 2.45 24727 5722 2 843.447916 422.7298 RelA-associated inhibitor OS=Homo sapiens OX=9606 GN=PPP1R13L PE=1 SV=4 5.81 1716.8 - 2.32E+06 - - - 3.4205 - 1.302 0.047 - 109.6 2 2 0 0.0029 8 0 0 0 1.82E+08 7.44E+07 - - - 0.0487 0.9988 221125_WJC_METTL3_EV_vs_WT_F03.05735.05735.2 0.0314 14-Jul R.FGGSYGGR.F sp|Q5BKZ1|ZN326_HUMAN 1 799.3613 1.21 24732 5735 2 799.360045 400.6879 DBIRD complex subunit ZNF326 OS=Homo sapiens OX=9606 GN=ZNF326 PE=1 SV=2 8.75 1718.4 - 2.31E+06 - - - -1.5725 - 1.436 0.338 - 92.3 1 2 0 -0.0013 8 0 0 0 1.55E+08 1.28E+08 - - - 2.6284 0.7882 221125_WJC_METTL3_EV_vs_WT_F03.05737.05737.2 3.8 12-Jun K.IVEEYAK.V sp|O95391|SLU7_HUMAN 1 850.4436 1.71 24733 5737 2 850.445221 426.2291 Pre-mRNA-splicing factor SLU7 OS=Homo sapiens OX=9606 GN=SLU7 PE=1 SV=2 4.53 1718.7 - 1.60E+06 - - - 1.8661 - 0.968 0.012 - 87.3 1 2 0 0.0016 7 0 0 0 7.71E+07 4.52E+07 - - - -0.9739 0.9954 221125_WJC_METTL3_EV_vs_WT_F03.05741.05741.2 0.583 12-Jul K.ITVVSEK.Q "sp|Q6P5R6|RL22L_HUMAN,tr|H0Y8C2|H0Y8C2_HUMAN,tr|C9JYQ9|C9JYQ9_HUMAN" 3 774.4487 1.26 24734 5741 2 774.446904 388.2316 60S ribosomal protein L22-like 1 OS=Homo sapiens OX=9606 GN=RPL22L1 PE=1 SV=2 6 1719.2 - 2.60E+07 - - - -2.3449 - 1.655 0.175 - 171.1 1 2 0 -0.0018 7 0 0 0 1.31E+09 1.05E+09 - - - 1.9293 0.9994 221125_WJC_METTL3_EV_vs_WT_F03.05746.05746.2 0.000495 14-Aug R.VMVTDADR.S "sp|P78347|GTF2I_HUMAN,tr|A0A494C1K3|A0A494C1K3_HUMAN" 2 905.4277 1.42 24736 5746 2 905.425547 453.7211 General transcription factor II-I OS=Homo sapiens OX=9606 GN=GTF2I PE=1 SV=2 4.21 1719.9 - 1.35E+07 - - - -2.3414 - 1.656 0.465 - 306.1 1 2 0 -0.0021 8 0 0 0 3.68E+09 2.59E+09 - - - 3.9961 0.991 221125_WJC_METTL3_EV_vs_WT_F03.05754.05754.2 0.09 14-May R.VPC[160.03]TPVAR.L sp|P61962|DCAF7_HUMAN 1 898.4695 5.21 24740 5754 2 898.467626 450.242 DDB1- and CUL4-associated factor 7 OS=Homo sapiens OX=9606 GN=DCAF7 PE=1 SV=1 8.22 1721 - 1.45E+06 - - - -2.0546 - 1.135 0.249 - 120.6 1 2 0 -0.0018 8 0 0 0 1.55E+08 2.97E+07 - - - 1.2615 0.9818 221125_WJC_METTL3_EV_vs_WT_F03.05760.05760.2 3.32 12-Aug R.LQASLTK[136.11].L "sp|Q13948|CASP_HUMAN,sp|P39880|CUX1_HUMAN,tr|A0A2R8Y852|A0A2R8Y852_HUMAN,tr|A0A2R8YDI1|A0A2R8YDI1_HUMAN" 4 767.4633 1.12 24742 5760 2 767.462347 384.7389 Protein CASP OS=Homo sapiens OX=9606 GN=CUX1 PE=1 SV=2 8.75 1721.8 - 3.53E+06 - - - -1.1818 - 1.529 0.001 - 183.9 1 2 0 -0.0009 7 0 0 0 4.29E+08 3.82E+08 - - - 0.3935 0.9997 221125_WJC_METTL3_EV_vs_WT_F03.05771.05771.2 3.76E-06 14-Aug K.C[160.03]EAAFATK.D "sp|P56270|MAZ_HUMAN,tr|H3BQI4|H3BQI4_HUMAN,tr|H3BQS2|H3BQS2_HUMAN,tr|I3L2Z5|I3L2Z5_HUMAN,tr|A0A087WWR2|A0A087WWR2_HUMAN" 5 896.4062 0.4 24746 5771 2 896.403999 449.2104 Myc-associated zinc finger protein OS=Homo sapiens OX=9606 GN=MAZ PE=1 SV=1 5.99 1723.2 - 1.91E+06 - - - -2.4587 - 1.819 0.554 - 295.3 1 2 0 -0.0022 8 0 0 0 1.87E+08 4.68E+08 - - - 4.9366 0.9999 221125_WJC_METTL3_EV_vs_WT_F03.05774.05774.2 1.59E-05 14-Nov K.C[160.03]EAAFATK[136.11].D "sp|P56270|MAZ_HUMAN,tr|H3BQI4|H3BQI4_HUMAN,tr|H3BQS2|H3BQS2_HUMAN,tr|I3L2Z5|I3L2Z5_HUMAN,tr|A0A087WWR2|A0A087WWR2_HUMAN" 5 904.4204 0.01 24748 5774 2 904.419859 453.2175 Myc-associated zinc finger protein OS=Homo sapiens OX=9606 GN=MAZ PE=1 SV=1 5.99 1723.5 - 1.90E+06 - - - -0.6015 - 2.268 0.521 - 829.4 1 2 0 -0.0005 8 0 0 0 1.99E+07 1.43E+09 - - - 5.3587 0.9968 221125_WJC_METTL3_EV_vs_WT_F03.05795.05795.2 0.382 12-Jun K.EVMVDDR[166.11].L "sp|P51149|RAB7A_HUMAN,tr|C9J592|C9J592_HUMAN,tr|C9J4V0|C9J4V0_HUMAN,tr|C9J7D1|C9J7D1_HUMAN,tr|A0A6Q8PH84|A0A6Q8PH84_HUMAN,tr|C9J8S3|C9J8S3_HUMAN,tr|C9IZZ0|C9IZZ0_HUMAN,tr|A0A6Q8PGE6|A0A6Q8PGE6_HUMAN,tr|A0A6Q8PF79|A0A6Q8PF79_HUMAN,tr|A0A6Q8PG52|A0A6Q8PG52_HUMAN" 10 872.3937 0.5 24757 5795 2 872.392366 437.2041 Ras-related protein Rab-7a OS=Homo sapiens OX=9606 GN=RAB7A PE=1 SV=1 4.03 1726.1 - 3.51E+06 - - - -1.5727 - 1.325 0.254 - 196.8 1 2 0 -0.0014 7 0 0 0 1.40E+08 2.79E+08 - - - 1.8083 0.9559 221125_WJC_METTL3_EV_vs_WT_F03.05798.05798.2 10.5 12-Jun K.ITVVSEK[136.11].Q "sp|Q6P5R6|RL22L_HUMAN,tr|H0Y8C2|H0Y8C2_HUMAN,tr|C9JYQ9|C9JYQ9_HUMAN" 3 782.4629 1.28 24759 5798 2 782.461994 392.2387 60S ribosomal protein L22-like 1 OS=Homo sapiens OX=9606 GN=RPL22L1 PE=1 SV=2 6 1726.4 - 9.35E+06 - - - -1.1834 - 1.251 0.059 - 77 7 2 0 -0.0009 7 0 0 0 1.41E+09 1.11E+09 - - - -0.1914 0.999 221125_WJC_METTL3_EV_vs_WT_F03.05807.05807.2 0.0573 12-Jun R.IEPSPYK[136.11].F sp|Q99805|TM9S2_HUMAN 1 840.4473 0.93 24762 5807 2 840.447421 421.2309 Transmembrane 9 superfamily member 2 OS=Homo sapiens OX=9606 GN=TM9SF2 PE=1 SV=1 6 1727.6 - 4.02E+06 - - - 0.1797 - 1.309 0.334 - 127.8 1 2 0 0.0002 7 0 0 0 3.44E+08 3.70E+08 - - - 2.3611 0.9979 221125_WJC_METTL3_EV_vs_WT_F03.05811.05811.2 0.0654 14-Jul K.LLNAAQER[166.11].E sp|Q13426|XRCC4_HUMAN 1 923.5064 0.67 24764 5811 2 923.504776 462.7605 DNA repair protein XRCC4 OS=Homo sapiens OX=9606 GN=XRCC4 PE=1 SV=2 6 1728.2 - 290375 - - - -1.7585 - 1.356 0.311 - 127.7 1 2 0 -0.0016 8 0 0 0 7.33E+06 1.09E+07 - - - 2.256 0.9957 221125_WJC_METTL3_EV_vs_WT_F03.05812.05812.2 0.716 12-Jul R.MATGLER[166.11].M "sp|P52272|HNRPM_HUMAN,tr|M0R2I7|M0R2I7_HUMAN,tr|A0A087X0X3|A0A087X0X3_HUMAN,tr|M0QZM1|M0QZM1_HUMAN" 4 786.3933 1.53 24765 5812 2 786.393106 394.2039 Heterogeneous nuclear ribonucleoprotein M OS=Homo sapiens OX=9606 GN=HNRNPM PE=1 SV=3 5.75 1728.2 - 6.04E+06 - - - -0.3026 - 1.504 0.119 - 222.3 1 2 0 -0.0002 7 0 0 0 2.11E+09 1.38E+09 - - - 1.213 0.9838 221125_WJC_METTL3_EV_vs_WT_F03.05819.05819.2 2.4 12-Jun R.IEPSPYK.F sp|Q99805|TM9S2_HUMAN 1 832.4331 0.92 24768 5819 2 832.433109 417.2238 Transmembrane 9 superfamily member 2 OS=Homo sapiens OX=9606 GN=TM9SF2 PE=1 SV=1 6 1729.1 - 4.67E+06 - - - 0.0469 - 1.134 0.116 - 140.4 1 2 0 0 7 0 0 0 3.37E+08 3.65E+08 - - - 0.2962 0.9967 221125_WJC_METTL3_EV_vs_WT_F03.05832.05832.2 0.385 12-Jul R.MATGLER.M "sp|P52272|HNRPM_HUMAN,tr|M0R2I7|M0R2I7_HUMAN,tr|A0A087X0X3|A0A087X0X3_HUMAN,tr|M0QZM1|M0QZM1_HUMAN" 4 776.3851 1.53 24774 5832 2 776.385707 389.1998 Heterogeneous nuclear ribonucleoprotein M OS=Homo sapiens OX=9606 GN=HNRNPM PE=1 SV=3 5.75 1730.7 - 3.56E+07 - - - 0.8153 - 1.613 0.134 - 213.5 1 2 0 0.0006 7 0 0 0 2.11E+09 1.38E+09 - - - 1.5454 0.8995 221125_WJC_METTL3_EV_vs_WT_F03.05837.05837.2 0.191 16-Jun K.VVETEDAYK.F "sp|Q15286|RAB35_HUMAN,tr|F5H157|F5H157_HUMAN" 2 1052.5026 1.13 24776 5837 2 1052.506677 527.2586 Ras-related protein Rab-35 OS=Homo sapiens OX=9606 GN=RAB35 PE=1 SV=1 4.14 1731.3 - 165500 - - - 3.8679 - 1.284 0.094 - 72.4 1 2 0 0.0041 9 0 0 0 2.88E+07 2.54E+07 - - - 0.4572 0.9983 221125_WJC_METTL3_EV_vs_WT_F03.05839.05839.2 0.109 12-Jul K.TPLQVAK[136.11].G "sp|O75832|PSD10_HUMAN,tr|B1AJY5|B1AJY5_HUMAN,tr|B1AJY7|B1AJY7_HUMAN" 3 763.4683 0.001 24777 5839 2 763.468791 382.7414 26S proteasome non-ATPase regulatory subunit 10 OS=Homo sapiens OX=9606 GN=PSMD10 PE=1 SV=1 8.41 1731.5 - 3.67E+06 - - - 0.592 - 1.558 0.213 - 242.6 1 2 0 0.0005 7 0 0 0 0.00E+00 1.58E+08 - - - 2.019 0.9998 221125_WJC_METTL3_EV_vs_WT_F03.05841.05841.3 0.00347 Oct-52 R.NVIHASDSVEGAQR.E "sp|O00746|NDKM_HUMAN,tr|Q4TT34|Q4TT34_HUMAN,tr|A0A087WVT9|A0A087WVT9_HUMAN,tr|F2Z2X0|F2Z2X0_HUMAN" 4 1481.7223 1.89 24779 5841 3 1481.7218 494.9147 "Nucleoside diphosphate kinase, mitochondrial OS=Homo sapiens OX=9606 GN=NME4 PE=1 SV=1" 5.32 1731.7 - 450790 - - - -0.3165 - 2.034 0.393 - 93.7 1 2 0 -0.0005 14 0 0 0 2.07E+07 1.10E+07 - - - 4.8083 0.9961 221125_WJC_METTL3_EV_vs_WT_F03.05845.05845.2 0.537 16-Jul R.GPAGPALGR.H sp|Q00587|BORG5_HUMAN 1 794.4399 1.93 24780 5845 2 794.439512 398.2272 Cdc42 effector protein 1 OS=Homo sapiens OX=9606 GN=CDC42EP1 PE=1 SV=1 9.75 1732.3 - 1.34E+06 - - - -0.4708 - 1.534 0.139 - 142 1 2 0 -0.0004 9 0 0 0 8.40E+08 4.35E+08 - - - 1.3054 0.9996 221125_WJC_METTL3_EV_vs_WT_F03.05846.05846.2 0.00942 16-Aug K.VVETEDAYK[136.11].F "sp|Q15286|RAB35_HUMAN,tr|F5H157|F5H157_HUMAN" 2 1060.5168 1.34 24781 5846 2 1060.5171 531.2657 Ras-related protein Rab-35 OS=Homo sapiens OX=9606 GN=RAB35 PE=1 SV=1 4.14 1732.4 - 263565 - - - 0.2772 - 1.653 0.395 - 175.3 1 2 0 0.0003 9 0 0 0 2.88E+07 2.16E+07 - - - 3.4124 0.8669 221125_WJC_METTL3_EV_vs_WT_F03.05847.05847.2 9.88 14-Jul R.GPGPLQER.S "sp|P43243|MATR3_HUMAN,tr|A8MXP9|A8MXP9_HUMAN,tr|D6R991|D6R991_HUMAN,tr|A0A0R4J2E8|A0A0R4J2E8_HUMAN,tr|H0Y8T4|H0Y8T4_HUMAN,tr|D6REM6|D6REM6_HUMAN" 6 852.4454 1.38 24782 5847 2 852.446402 427.23 Matrin-3 OS=Homo sapiens OX=9606 GN=MATR3 PE=1 SV=2 6 1732.5 - 2.41E+06 - - - 1.2153 - 1.126 0.023 - 92.5 9 2 0 0.001 8 0 0 0 1.00E+10 7.28E+09 - - - -0.8578 0.9993 221125_WJC_METTL3_EV_vs_WT_F03.05850.05850.2 0.18 14-Aug R.ILAAETDR[166.11].L "sp|Q9GZS1|RPA49_HUMAN,tr|E7EX70|E7EX70_HUMAN" 2 897.4795 0.61 24783 5850 2 897.47897 449.747 DNA-directed RNA polymerase I subunit RPA49 OS=Homo sapiens OX=9606 GN=POLR1E PE=1 SV=3 4.37 1732.9 - 1.35E+06 - - - -0.6084 - 1.676 0.293 - 171.6 1 2 0 -0.0005 8 0 0 0 4.52E+07 7.45E+07 - - - 2.7624 0.9991 221125_WJC_METTL3_EV_vs_WT_F03.05851.05851.2 0.131 16-Sep R.GPAGPALGR[166.11].H sp|Q00587|BORG5_HUMAN 1 804.4482 1.98 24784 5851 2 804.44756 403.2314 Cdc42 effector protein 1 OS=Homo sapiens OX=9606 GN=CDC42EP1 PE=1 SV=1 9.75 1733 - 1.20E+06 - - - -0.7409 - 1.815 0.237 - 360.6 1 2 0 -0.0006 9 0 0 0 8.62E+08 4.35E+08 - - - 2.5158 0.9439 221125_WJC_METTL3_EV_vs_WT_F03.05855.05855.2 5.11 12-May R.SVDETLR[166.11].L "sp|Q06830|PRDX1_HUMAN,sp|Q13162|PRDX4_HUMAN,tr|A0A0A0MRQ5|A0A0A0MRQ5_HUMAN,tr|H7C3T4|H7C3T4_HUMAN,tr|A0A0A0MSI0|A0A0A0MSI0_HUMAN" 5 828.4217 0.68 24786 5855 2 828.42147 415.2181 Peroxiredoxin-1 OS=Homo sapiens OX=9606 GN=PRDX1 PE=1 SV=1 4.37 1733.4 - 4.19E+06 - - - -0.2378 - 0.878 0.116 - 74.3 1 2 0 -0.0002 7 0 0 0 1.99E+09 2.91E+09 - - - -0.5145 0.9994 221125_WJC_METTL3_EV_vs_WT_F03.05864.05864.2 0.0621 12-Jul K.LAEPYGK[136.11].L "sp|P43243|MATR3_HUMAN,tr|B3KM87|B3KM87_HUMAN,tr|A8MXP9|A8MXP9_HUMAN,tr|D6RBK5|D6RBK5_HUMAN,tr|A0A0R4J2E8|A0A0R4J2E8_HUMAN,tr|H0Y8T4|H0Y8T4_HUMAN,tr|D6REM6|D6REM6_HUMAN" 7 784.4211 1.27 24790 5864 2 784.420405 393.2178 Matrin-3 OS=Homo sapiens OX=9606 GN=MATR3 PE=1 SV=2 6 1734.5 - 4.23E+07 - - - -0.8286 - 1.57 0.326 - 182.6 1 2 0 -0.0006 7 0 0 0 2.05E+10 1.62E+10 - - - 2.8779 0.9911 221125_WJC_METTL3_EV_vs_WT_F03.05871.05871.3 0.104 Sep-52 R.NVIHASDSVEGAQR[166.11].E "sp|O00746|NDKM_HUMAN,tr|Q4TT34|Q4TT34_HUMAN,tr|A0A087WVT9|A0A087WVT9_HUMAN,tr|F2Z2X0|F2Z2X0_HUMAN" 4 1491.7305 1.92 24794 5871 3 1491.731163 498.2508 "Nucleoside diphosphate kinase, mitochondrial OS=Homo sapiens OX=9606 GN=NME4 PE=1 SV=1" 5.32 1735.4 - 348753 - - - 0.4183 - 1.532 0.21 - 65.6 2 2 0 0.0006 14 0 0 0 2.07E+07 1.08E+07 - - - 1.8754 0.9956 221125_WJC_METTL3_EV_vs_WT_F03.05875.05875.2 0.335 14-Aug R.VISSIEQK[136.11].T "sp|P31946|1433B_HUMAN,sp|P27348|1433T_HUMAN,sp|Q04917|1433F_HUMAN,sp|P31947|1433S_HUMAN,sp|P61981|1433G_HUMAN,tr|Q4VY19|Q4VY19_HUMAN,tr|A0A0J9YWZ2|A0A0J9YWZ2_HUMAN,tr|Q4VY20|Q4VY20_HUMAN,tr|A2IDB2|A2IDB2_HUMAN,tr|E9PG15|E9PG15_HUMAN,tr|A0A0J9YWE8|A0A0J9YWE8_HUMAN" 11 910.5215 1.04 24796 5875 2 910.520162 456.268 14-3-3 protein beta\alpha OS=Homo sapiens OX=9606 GN=YWHAB PE=1 SV=3 5.97 1735.9 - 1.20E+06 - - - -1.4662 - 1.489 0.172 - 177.7 1 2 0 -0.0013 8 0 0 0 1.12E+09 1.08E+09 - - - 1.5116 0.9897 221125_WJC_METTL3_EV_vs_WT_F03.05876.05876.2 0.273 14-Jul R.VISSIEQK.T "sp|P31946|1433B_HUMAN,sp|P27348|1433T_HUMAN,sp|Q04917|1433F_HUMAN,sp|P31947|1433S_HUMAN,sp|P61981|1433G_HUMAN,tr|Q4VY19|Q4VY19_HUMAN,tr|A0A0J9YWZ2|A0A0J9YWZ2_HUMAN,tr|Q4VY20|Q4VY20_HUMAN,tr|A2IDB2|A2IDB2_HUMAN,tr|E9PG15|E9PG15_HUMAN,tr|A0A0J9YWE8|A0A0J9YWE8_HUMAN" 11 902.5073 1.04 24797 5876 2 902.507718 452.2609 14-3-3 protein beta\alpha OS=Homo sapiens OX=9606 GN=YWHAB PE=1 SV=3 5.97 1736 - 920103 - - - 0.4665 - 1.18 0.179 - 104.8 3 2 0 0.0004 8 0 0 0 1.12E+09 1.08E+09 - - - 0.649 0.9981 221125_WJC_METTL3_EV_vs_WT_F03.05879.05879.2 0.0816 14-Jul K.LIEEETAR.R sp|Q9NWB6|ARGL1_HUMAN 1 959.4924 0.79 24800 5879 2 959.490304 480.7535 Arginine and glutamate-rich protein 1 OS=Homo sapiens OX=9606 GN=ARGLU1 PE=1 SV=1 4.25 1736.4 - 255415 - - - -2.1584 - 1.357 0.357 - 144.5 1 2 0 -0.0021 8 0 0 0 9.70E+07 1.24E+08 - - - 2.5979 0.8697 221125_WJC_METTL3_EV_vs_WT_F03.05881.05881.2 0.234 14-Aug R.ILAAETDR.L "sp|Q9GZS1|RPA49_HUMAN,tr|E7EX70|E7EX70_HUMAN" 2 887.4712 0.6 24801 5881 2 887.467681 444.7429 DNA-directed RNA polymerase I subunit RPA49 OS=Homo sapiens OX=9606 GN=POLR1E PE=1 SV=3 4.37 1736.6 - 1.47E+06 - - - -4.017 - 1.4 0.036 - 181.6 1 2 0 -0.0036 8 0 0 0 4.49E+07 7.54E+07 - - - 0.3206 0.9878 221125_WJC_METTL3_EV_vs_WT_F03.05883.05883.2 0.0261 12-Jul K.LAEPYGK.L "sp|P43243|MATR3_HUMAN,tr|B3KM87|B3KM87_HUMAN,tr|A8MXP9|A8MXP9_HUMAN,tr|D6RBK5|D6RBK5_HUMAN,tr|A0A0R4J2E8|A0A0R4J2E8_HUMAN,tr|H0Y8T4|H0Y8T4_HUMAN,tr|D6REM6|D6REM6_HUMAN" 7 776.4069 1.27 24802 5883 2 776.40303 389.2107 Matrin-3 OS=Homo sapiens OX=9606 GN=MATR3 PE=1 SV=2 6 1736.8 - 1.79E+08 - - - -4.9265 - 1.455 0.338 - 192.5 1 2 0 -0.0038 7 0 0 0 2.05E+10 1.61E+10 - - - 2.7245 0.9793 221125_WJC_METTL3_EV_vs_WT_F03.05884.05884.2 0.391 12-Sep R.LAQDPYR[166.11].L sp|P18583|SON_HUMAN 1 871.4427 1.07 24803 5884 2 871.440721 436.7286 Protein SON OS=Homo sapiens OX=9606 GN=SON PE=1 SV=4 5.84 1736.9 - 3.38E+06 - - - -2.3134 - 1.384 0.098 - 330 1 2 0 -0.002 7 0 0 0 8.83E+08 8.24E+08 - - - 0.7939 0.9921 221125_WJC_METTL3_EV_vs_WT_F03.05888.05888.2 0.824 14-Jul R.IFQAENAK.L sp|Q8IYI6|EXOC8_HUMAN 1 919.4763 2.75 24805 5888 2 919.473674 460.7454 Exocyst complex component 8 OS=Homo sapiens OX=9606 GN=EXOC8 PE=1 SV=2 6 1737.4 - 762481 - - - -2.8897 - 1.596 0.186 - 143.2 1 2 0 -0.0027 8 0 0 0 5.71E+07 2.08E+07 - - - 1.8239 0.997 221125_WJC_METTL3_EV_vs_WT_F03.05891.05891.2 0.376 14-Jul K.LIEEETAR[166.11].R sp|Q9NWB6|ARGL1_HUMAN 1 969.5006 0.78 24806 5891 2 969.500031 485.7576 Arginine and glutamate-rich protein 1 OS=Homo sapiens OX=9606 GN=ARGLU1 PE=1 SV=1 4.25 1737.8 - 1.45E+06 - - - -0.6333 - 1.527 0.162 - 136.9 1 2 0 -0.0006 8 0 0 0 9.70E+07 1.24E+08 - - - 1.514 0.9931 221125_WJC_METTL3_EV_vs_WT_F03.05895.05895.2 0.0134 14-Aug R.MLAQQAVK[136.11].R "sp|P04844|RPN2_HUMAN,tr|Q5JYR3|Q5JYR3_HUMAN" 2 895.5041 1.88 24808 5895 2 895.501907 448.7593 Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit 2 OS=Homo sapiens OX=9606 GN=RPN2 PE=1 SV=3 8.5 1738.3 - 1.71E+06 - - - -2.4187 - 1.217 0.274 - 195.8 1 2 0 -0.0022 8 0 0 0 2.07E+08 1.10E+08 - - - 1.6564 0.9989 221125_WJC_METTL3_EV_vs_WT_F03.05896.05896.2 0.00762 14-Jul K.VANASYYR[166.11].K "sp|O15042|SR140_HUMAN,tr|E7ET15|E7ET15_HUMAN" 2 952.4642 0.52 24809 5896 2 952.462996 477.2394 U2 snRNP-associated SURP motif-containing protein OS=Homo sapiens OX=9606 GN=U2SURP PE=1 SV=2 8.56 1738.4 - 526951 - - - -1.2641 - 1.359 0.348 - 176.4 1 2 0 -0.0012 8 0 0 0 2.68E+07 5.20E+07 - - - 2.5361 0.9684 221125_WJC_METTL3_EV_vs_WT_F03.05925.05925.2 6.23 12-Jul R.TVYGAVR.A "sp|O43251|RFOX2_HUMAN,tr|B0QYV1|B0QYV1_HUMAN,tr|B0QYY4|B0QYY4_HUMAN,tr|A0A0G2JRD1|A0A0G2JRD1_HUMAN,tr|A0A0G2JRA5|A0A0G2JRA5_HUMAN,tr|S4R3K7|S4R3K7_HUMAN" 6 764.4181 1.08 24813 5925 2 764.417434 383.2163 RNA binding protein fox-1 homolog 2 OS=Homo sapiens OX=9606 GN=RBFOX2 PE=1 SV=3 8.41 1743 - 2.25E+06 - - - -0.8556 - 1.006 0.119 - 178 1 2 0 -0.0007 7 0 0 0 4.35E+08 4.04E+08 - - - -0.0613 0.8923 221125_WJC_METTL3_EV_vs_WT_F03.05928.05928.2 0.043 14-Jul Y.LASGSFDK.C "sp|Q9BZK7|TBL1R_HUMAN,sp|O60907|TBL1X_HUMAN,sp|Q9BQ87|TBL1Y_HUMAN,sp|Q96J01|THOC3_HUMAN,tr|D6RGZ2|D6RGZ2_HUMAN,tr|A0A494C153|A0A494C153_HUMAN,tr|A0A804HJZ5|A0A804HJZ5_HUMAN,tr|A0A2R8YFW3|A0A2R8YFW3_HUMAN,tr|A0A0D9SF63|A0A0D9SF63_HUMAN,tr|A0A0D9SFI2|A0A0D9SFI2_HUMAN" 10 823.4076 0.27 24815 5928 2 823.405684 412.7111 F-box-like\WD repeat-containing protein TBL1XR1 OS=Homo sapiens OX=9606 GN=TBL1XR1 PE=1 SV=1 5.84 1743.2 - 2.47E+06 - - - -2.3063 - 1.432 0.34 - 120.6 1 1 0 -0.0019 8 0 0 0 1.11E+08 4.09E+08 - - - 2.6346 0.9839 221125_WJC_METTL3_EV_vs_WT_F03.05932.05932.2 0.0369 12-Jul R.TEGVLER[166.11].Q "sp|Q9BV19|CA050_HUMAN,tr|R4GMT4|R4GMT4_HUMAN,tr|B4DSR2|B4DSR2_HUMAN" 3 812.4268 0.24 24816 5932 2 812.42313 407.2207 Uncharacterized protein C1orf50 OS=Homo sapiens OX=9606 GN=C1orf50 PE=1 SV=2 4.53 1743.8 - 1.75E+06 - - - -4.4582 - 1.473 0.258 - 268.6 1 2 0 -0.0036 7 0 0 0 1.25E+08 5.24E+08 - - - 2.1726 0.9988 221125_WJC_METTL3_EV_vs_WT_F03.05942.05942.2 0.398 14-Aug R.GPGPLQER[166.11].S "sp|P43243|MATR3_HUMAN,tr|A8MXP9|A8MXP9_HUMAN,tr|D6R991|D6R991_HUMAN,tr|A0A0R4J2E8|A0A0R4J2E8_HUMAN,tr|H0Y8T4|H0Y8T4_HUMAN,tr|D6REM6|D6REM6_HUMAN" 6 862.4536 1.38 24818 5942 2 862.453738 432.2341 Matrin-3 OS=Homo sapiens OX=9606 GN=MATR3 PE=1 SV=2 6 1745.3 - 1.93E+07 - - - 0.1183 - 1.635 0.233 - 270.3 1 2 0 0.0001 8 0 0 0 1.01E+10 7.32E+09 - - - 2.2447 0.9358 221125_WJC_METTL3_EV_vs_WT_F03.05953.05953.2 3.33 14-Jun R.LVNQEIEK.F sp|O75525|KHDR3_HUMAN 1 971.5288 1.51 24821 5953 2 971.528308 486.7717 "KH domain-containing, RNA-binding, signal transduction-associated protein 3 OS=Homo sapiens OX=9606 GN=KHDRBS3 PE=1 SV=1" 4.53 1746.8 - 328605 - - - -0.4663 - 1.048 0.06 - 70.8 3 2 0 -0.0005 8 0 0 0 5.50E+07 3.64E+07 - - - -0.5877 0.9943 221125_WJC_METTL3_EV_vs_WT_F03.05955.05955.2 0.0442 12-May R.LGQDPYR.L sp|P18583|SON_HUMAN 1 847.4188 1.18 24822 5955 2 847.418177 424.7167 Protein SON OS=Homo sapiens OX=9606 GN=SON PE=1 SV=4 5.84 1747.1 - 8.06E+06 - - - -0.7552 - 1.265 0.174 - 83.8 1 2 0 -0.0006 7 0 0 0 5.75E+08 4.88E+08 - - - 1.0708 0.9983 221125_WJC_METTL3_EV_vs_WT_F03.05966.05966.2 0.717 14-Jul R.LVEVDSSR[166.11].Q sp|Q03252|LMNB2_HUMAN 1 913.4744 1.43 24826 5966 2 913.474644 457.7445 Lamin-B2 OS=Homo sapiens OX=9606 GN=LMNB2 PE=1 SV=4 4.37 1748.5 - 2.08E+06 - - - 0.2332 - 1.536 0.22 - 161.6 1 2 0 0.0002 8 0 0 0 1.88E+08 1.31E+08 - - - 1.9602 0.8645 221125_WJC_METTL3_EV_vs_WT_F03.05971.05971.2 3.82 14-May R.EPMQTGIK[136.11].A "sp|P25705|ATPA_HUMAN,tr|K7ERX7|K7ERX7_HUMAN,tr|K7EK77|K7EK77_HUMAN,tr|K7EJP1|K7EJP1_HUMAN,tr|K7ENJ4|K7ENJ4_HUMAN" 5 910.4674 1.47 24827 5971 2 910.464354 456.241 "ATP synthase subunit alpha, mitochondrial OS=Homo sapiens OX=9606 GN=ATP5F1A PE=1 SV=1" 6.1 1749.2 - 3.04E+06 - - - -3.2939 - 1.047 0.123 - 84 2 2 0 -0.003 8 0 0 0 3.22E+08 2.19E+08 - - - -0.0474 0.9966 221125_WJC_METTL3_EV_vs_WT_F03.05981.05981.2 1.45 12-Jul K.LGELSDK[136.11].L sp|Q14677|EPN4_HUMAN 1 768.4109 1.03 24831 5981 2 768.410481 385.2127 Clathrin interactor 1 OS=Homo sapiens OX=9606 GN=CLINT1 PE=1 SV=1 4.37 1750.6 - 3.12E+06 - - - -0.5245 - 1.509 0.145 - 140 1 2 0 -0.0004 7 0 0 0 2.40E+09 2.33E+09 - - - 1.4155 0.9982 221125_WJC_METTL3_EV_vs_WT_F03.05984.05984.2 0.215 14-Jun K.LLQEAEQR.L "sp|Q9H9E3|COG4_HUMAN,tr|A0A0A0MS45|A0A0A0MS45_HUMAN,tr|J3KNI1|J3KNI1_HUMAN,tr|A0A6I8PIQ6|A0A6I8PIQ6_HUMAN,tr|J3KRB5|J3KRB5_HUMAN" 5 985.5193 0.61 24832 5984 2 985.519498 493.7669 Conserved oligomeric Golgi complex subunit 4 OS=Homo sapiens OX=9606 GN=COG4 PE=1 SV=3 4.53 1751 - 292869 - - - 0.2425 - 1.354 0.262 - 96.9 1 2 0 0.0002 8 0 0 0 5.49E+06 9.02E+06 - - - 1.8901 0.9931 221125_WJC_METTL3_EV_vs_WT_F03.05987.05987.2 0.101 16-Jul R.QFTSSSSIK.G sp|Q04695|K1C17_HUMAN 1 983.4924 149.51 24833 5987 2 983.491092 492.7535 "Keratin, type I cytoskeletal 17 OS=Homo sapiens OX=9606 GN=KRT17 PE=1 SV=2" 8.75 1751.4 - 197526 - - - -1.3045 - 1.197 0.209 - 116.3 1 2 0 -0.0013 9 0 0 0 8.08E+06 5.41E+04 - - - 1.1045 0.9976 221125_WJC_METTL3_EV_vs_WT_F03.05991.05991.2 0.0659 12-Sep M.PELAVQK[136.11].V "sp|P51665|PSMD7_HUMAN,tr|H3BNT7|H3BNT7_HUMAN,tr|H3BQV2|H3BQV2_HUMAN,tr|H3BTM8|H3BTM8_HUMAN" 4 791.4633 0.74 24835 5991 2 791.462656 396.7389 26S proteasome non-ATPase regulatory subunit 7 OS=Homo sapiens OX=9606 GN=PSMD7 PE=1 SV=2 6.43 1751.8 - 4.34E+06 - - - -0.7556 - 1.839 0.101 - 324.6 1 2 0 -0.0006 7 0 0 0 1.60E+08 2.18E+08 - - - 1.7172 0.9929 221125_WJC_METTL3_EV_vs_WT_F03.05998.05998.2 0.395 12-May R.FQTMEEK.K "sp|P39023|RL3_HUMAN,tr|G5E9G0|G5E9G0_HUMAN" 2 911.4059 0.92 24839 5998 2 911.405108 456.7102 60S ribosomal protein L3 OS=Homo sapiens OX=9606 GN=RPL3 PE=1 SV=2 4.53 1752.5 - 1.85E+06 - - - -0.835 - 0.95 0.279 - 58.7 1 2 0 -0.0008 7 0 0 0 5.65E+07 6.12E+07 - - - 0.9389 0.9965 221125_WJC_METTL3_EV_vs_WT_F03.06004.06004.2 0.0838 16-Aug R.AAVPDAVGK.C "sp|P05023|AT1A1_HUMAN,sp|P13637|AT1A3_HUMAN,sp|P50993|AT1A2_HUMAN,tr|A0A0A0MT26|A0A0A0MT26_HUMAN,tr|H0Y7C1|H0Y7C1_HUMAN,tr|A0A2R8YEY8|A0A2R8YEY8_HUMAN,tr|B1AKY9|B1AKY9_HUMAN,tr|M0R116|M0R116_HUMAN" 8 826.4549 0.06 24841 6004 2 826.453819 414.2347 Sodium\potassium-transporting ATPase subunit alpha-1 OS=Homo sapiens OX=9606 GN=ATP1A1 PE=1 SV=1 5.88 1753.3 - 3.24E+06 - - - -1.2693 - 1.55 0.173 - 204.8 1 2 0 -0.001 9 0 0 0 1.14E+08 2.06E+09 - - - 1.5863 0.9983 221125_WJC_METTL3_EV_vs_WT_F03.06007.06007.2 0.313 12-Jul K.LGELSDK.L sp|Q14677|EPN4_HUMAN 1 760.3967 1.03 24842 6007 2 760.395849 381.2056 Clathrin interactor 1 OS=Homo sapiens OX=9606 GN=CLINT1 PE=1 SV=1 4.37 1753.7 - 2.37E+07 - - - -1.0981 - 1.544 0.23 - 145.3 1 2 0 -0.0008 7 0 0 0 2.40E+09 2.33E+09 - - - 2.1159 0.9998 221125_WJC_METTL3_EV_vs_WT_F03.06012.06012.2 0.00299 16-Oct K.YLATC[160.03]ADDR.T "sp|Q9Y4P3|TBL2_HUMAN,tr|F8WDI9|F8WDI9_HUMAN,tr|E9PF19|E9PF19_HUMAN,tr|Q96E41|Q96E41_HUMAN,tr|A0A087WXC6|A0A087WXC6_HUMAN" 5 1083.4655 1.21 24844 6012 2 1083.463701 542.74 Transducin beta-like protein 2 OS=Homo sapiens OX=9606 GN=TBL2 PE=1 SV=1 4.21 1754.4 - 285951 - - - -1.6687 - 2.104 0.577 - 313.4 1 2 0 -0.0018 9 0 0 0 1.62E+07 1.34E+07 - - - 5.4541 0.9939 221125_WJC_METTL3_EV_vs_WT_F03.06016.06016.2 0.243 14-Jun R.EPMQTGIK.A "sp|P25705|ATPA_HUMAN,tr|K7ERX7|K7ERX7_HUMAN,tr|K7EK77|K7EK77_HUMAN,tr|K7EJP1|K7EJP1_HUMAN,tr|K7ENJ4|K7ENJ4_HUMAN" 5 902.4532 1.47 24846 6016 2 902.45149 452.2339 "ATP synthase subunit alpha, mitochondrial OS=Homo sapiens OX=9606 GN=ATP5F1A PE=1 SV=1" 6.1 1754.8 - 1.52E+06 - - - -1.8428 - 1.249 0.234 - 137.7 1 2 0 -0.0017 8 0 0 0 3.22E+08 2.19E+08 - - - 1.4394 0.9994 221125_WJC_METTL3_EV_vs_WT_F03.06020.06020.2 0.0058 14-Sep R.MGANSLER.M "sp|P52272|HNRPM_HUMAN,sp|P52272|HNRPM_HUMAN,tr|M0R2I7|M0R2I7_HUMAN,tr|M0QY96|M0QY96_HUMAN,tr|A0A087X0X3|A0A087X0X3_HUMAN,tr|M0QZM1|M0QZM1_HUMAN,tr|M0QZM1|M0QZM1_HUMAN" 7 876.4124 1.61 24847 6020 2 876.410862 439.2135 Heterogeneous nuclear ribonucleoprotein M OS=Homo sapiens OX=9606 GN=HNRNPM PE=1 SV=3 5.75 1755.4 - 4.98E+06 - - - -1.699 - 1.579 0.407 - 230.2 1 2 0 -0.0015 8 0 0 0 4.49E+09 2.80E+09 - - - 3.4243 0.9996 221125_WJC_METTL3_EV_vs_WT_F03.06022.06022.2 0.0176 14-Sep R.MGANSLER[166.11].M "sp|P52272|HNRPM_HUMAN,sp|P52272|HNRPM_HUMAN,tr|M0R2I7|M0R2I7_HUMAN,tr|M0QY96|M0QY96_HUMAN,tr|A0A087X0X3|A0A087X0X3_HUMAN,tr|M0QZM1|M0QZM1_HUMAN,tr|M0QZM1|M0QZM1_HUMAN" 7 886.4206 1.61 24848 6022 2 886.419032 444.2176 Heterogeneous nuclear ribonucleoprotein M OS=Homo sapiens OX=9606 GN=HNRNPM PE=1 SV=3 5.75 1755.6 - 5.27E+06 - - - -1.7926 - 1.792 0.417 - 351.3 1 2 0 -0.0016 8 0 0 0 4.49E+09 2.80E+09 - - - 3.8798 0.9989 221125_WJC_METTL3_EV_vs_WT_F03.06041.06041.2 0.591 14-Sep R.IIEVSGQK[136.11].L "sp|P61106|RAB14_HUMAN,tr|X6RFL8|X6RFL8_HUMAN" 2 880.5109 0.95 24853 6041 2 880.509707 441.2627 Ras-related protein Rab-14 OS=Homo sapiens OX=9606 GN=RAB14 PE=1 SV=4 6 1758.3 - 2.83E+06 - - - -1.3924 - 1.672 0.271 - 177.4 1 2 0 -0.0012 8 0 0 0 1.39E+08 1.46E+08 - - - 2.5925 0.9938 221125_WJC_METTL3_EV_vs_WT_F03.06043.06043.2 0.763 16-Jul R.IQAGDPVAR.Y "sp|P19388|RPAB1_HUMAN,tr|A0A0A0MQR7|A0A0A0MQR7_HUMAN,tr|A0A087WVZ9|A0A087WVZ9_HUMAN,tr|A0A087WWX0|A0A087WWX0_HUMAN" 4 925.4981 2.06 24855 6043 2 925.49721 463.7563 "DNA-directed RNA polymerases I, II, and III subunit RPABC1 OS=Homo sapiens OX=9606 GN=POLR2E PE=1 SV=4" 5.84 1758.5 - 1.09E+06 - - - -0.9941 - 1.441 0.15 - 133.2 2 2 0 -0.0009 9 0 0 0 7.48E+07 3.62E+07 - - - 1.0711 0.9952 221125_WJC_METTL3_EV_vs_WT_F03.06044.06044.2 0.0468 16-Aug R.VTEEAVAVK[136.11].L "sp|O14757|CHK1_HUMAN,tr|E9PKQ3|E9PKQ3_HUMAN,tr|E9PQW7|E9PQW7_HUMAN,tr|E9PJI4|E9PJI4_HUMAN" 4 952.5321 1.65 24856 6044 2 952.529825 477.2733 Serine\threonine-protein kinase Chk1 OS=Homo sapiens OX=9606 GN=CHEK1 PE=1 SV=2 4.53 1758.6 - 856644 - - - -2.3485 - 1.653 0.191 - 186.1 1 2 0 -0.0022 9 0 0 0 7.46E+07 4.51E+07 - - - 1.905 0.9677 221125_WJC_METTL3_EV_vs_WT_F03.06052.06052.2 0.934 12-May R.LPPEVNR.L sp|Q9Y3B4|SF3B6_HUMAN 1 823.4552 1.24 24859 6052 2 823.453242 412.7349 Splicing factor 3B subunit 6 OS=Homo sapiens OX=9606 GN=SF3B6 PE=1 SV=1 6 1759.6 - 1.86E+06 - - - -2.3802 - 1.23 0.14 - 94.1 3 2 0 -0.002 7 0 0 0 3.19E+08 2.57E+08 - - - 0.5172 0.9937 221125_WJC_METTL3_EV_vs_WT_F03.06064.06064.2 0.156 14-Jul R.STLEPVEK[136.11].A "sp|P48741|HSP77_HUMAN,sp|P0DMV8|HS71A_HUMAN,sp|P0DMV9|HS71B_HUMAN,sp|P17066|HSP76_HUMAN,tr|V9GZ37|V9GZ37_HUMAN,tr|A0A0G2JIW1|A0A0G2JIW1_HUMAN" 6 909.4899 0.13 24863 6064 2 909.487915 455.7522 Putative heat shock 70 kDa protein 7 OS=Homo sapiens OX=9606 GN=HSPA7 PE=5 SV=2 4.53 1761.2 - 1.16E+06 - - - -2.1419 - 1.491 0.179 - 195.7 1 2 0 -0.0019 8 0 0 0 4.70E+08 3.51E+09 - - - 1.5672 0.9802 221125_WJC_METTL3_EV_vs_WT_F03.06067.06067.2 3.43 12-May R.ILNVSNK.G "sp|Q9H4A3|WNK1_HUMAN,tr|F5GWT4|F5GWT4_HUMAN,tr|A0A6Q8PFM0|A0A6Q8PFM0_HUMAN" 3 786.46 0.81 24864 6067 2 786.460374 394.2373 Serine\threonine-protein kinase WNK1 OS=Homo sapiens OX=9606 GN=WNK1 PE=1 SV=2 8.75 1761.6 - 1.76E+06 - - - 0.5353 - 1.045 0.16 - 47.8 2 2 0 0.0004 7 0 0 0 1.32E+08 1.62E+08 - - - 0.2276 0.9992 221125_WJC_METTL3_EV_vs_WT_F03.06076.06076.2 0.321 14-Jul R.GPGPLQER.S "sp|P43243|MATR3_HUMAN,tr|A8MXP9|A8MXP9_HUMAN,tr|D6R991|D6R991_HUMAN,tr|A0A0R4J2E8|A0A0R4J2E8_HUMAN,tr|H0Y8T4|H0Y8T4_HUMAN,tr|D6REM6|D6REM6_HUMAN" 6 852.4454 1.38 24868 6076 2 852.444913 427.23 Matrin-3 OS=Homo sapiens OX=9606 GN=MATR3 PE=1 SV=2 6 1762.7 - 6.17E+07 - - - -0.5314 - 1.615 0.279 - 208.4 1 2 0 -0.0005 8 0 0 0 1.00E+10 7.28E+09 - - - 2.5472 0.9996 221125_WJC_METTL3_EV_vs_WT_F03.06088.06088.2 0.00459 16-Aug R.VNGSLAVSR.A "sp|O75688|PPM1B_HUMAN,sp|P35813|PPM1A_HUMAN,tr|B8ZZF0|B8ZZF0_HUMAN,tr|A0A3B3IS24|A0A3B3IS24_HUMAN,tr|C9JIR6|C9JIR6_HUMAN" 5 901.4981 5.87 24869 6088 2 901.498496 451.7563 Protein phosphatase 1B OS=Homo sapiens OX=9606 GN=PPM1B PE=1 SV=1 9.72 1764.7 - 931834 - - - 0.406 - 1.631 0.371 - 187.5 1 2 0 0.0004 9 0 0 0 1.26E+07 2.15E+06 - - - 3.1964 0.7867 221125_WJC_METTL3_EV_vs_WT_F03.06099.06099.2 0.00416 14-Sep R.MGANSLER[166.11].M "sp|P52272|HNRPM_HUMAN,sp|P52272|HNRPM_HUMAN,tr|M0R2I7|M0R2I7_HUMAN,tr|M0QY96|M0QY96_HUMAN,tr|A0A087X0X3|A0A087X0X3_HUMAN,tr|M0QZM1|M0QZM1_HUMAN,tr|M0QZM1|M0QZM1_HUMAN" 7 886.4206 1.61 24875 6099 2 888.425447 444.2176 Heterogeneous nuclear ribonucleoprotein M OS=Homo sapiens OX=9606 GN=HNRNPM PE=1 SV=3 5.75 1766.1 - 1.05E+07 - - - 2261.7096 - 2.007 0.413 - 302.4 1 2 0 2.0048 8 0 0 0 4.49E+09 2.80E+09 - - - 3.5629 0.9995 221125_WJC_METTL3_EV_vs_WT_F03.06102.06102.2 0.0233 12-Jul R.GPMLDQR.G "sp|P33240|CSTF2_HUMAN,sp|Q9H0L4|CSTFT_HUMAN,tr|E9PID8|E9PID8_HUMAN,tr|E7EWR4|E7EWR4_HUMAN" 4 815.396 1.89 24876 6102 2 815.396284 408.7053 Cleavage stimulation factor subunit 2 OS=Homo sapiens OX=9606 GN=CSTF2 PE=1 SV=1 5.84 1766.5 - 2.44E+06 - - - 0.3814 - 1.445 0.403 - 286.7 1 2 0 0.0003 7 0 0 0 2.17E+08 1.15E+08 - - - 3.1838 0.9985 221125_WJC_METTL3_EV_vs_WT_F03.06118.06118.2 0.017 16-Aug K.QDSGHLDLR[166.11].N "sp|Q86U44|MTA70_HUMAN,tr|B4E349|B4E349_HUMAN,tr|F5H6D8|F5H6D8_HUMAN,tr|B4DTN4|B4DTN4_HUMAN" 4 1049.5129 0 24881 6118 2 1049.511033 525.7637 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 5.21 1768.7 - 543996 - - - -1.818 - 1.495 0.326 - 209.5 1 2 0 -0.0019 9 0 0 0 6.66E+04 2.96E+07 - - - 2.6116 0.9994 221125_WJC_METTL3_EV_vs_WT_F03.06119.06119.2 0.201 14-Aug R.LVEVDSGR.Q "sp|P20700|LMNB1_HUMAN,tr|E9PBF6|E9PBF6_HUMAN,tr|A0A0D9SFE5|A0A0D9SFE5_HUMAN" 3 873.4556 0.98 24882 6119 2 873.455842 437.7351 Lamin-B1 OS=Homo sapiens OX=9606 GN=LMNB1 PE=1 SV=2 4.37 1768.8 - 1.08E+07 - - - 0.2816 - 1.53 0.339 - 259.5 1 2 0 0.0002 8 0 0 0 8.57E+08 8.77E+08 - - - 2.8274 0.9131 221125_WJC_METTL3_EV_vs_WT_F03.06124.06124.2 6.23 14-May K.VHPAVVIR.Q "sp|P62829|RL23_HUMAN,tr|J3QQT9|J3QQT9_HUMAN,tr|J3KT29|J3KT29_HUMAN,tr|J3KTJ3|J3KTJ3_HUMAN,tr|C9JD32|C9JD32_HUMAN" 5 889.5498 1.04 24885 6124 2 889.549683 445.7822 60S ribosomal protein L23 OS=Homo sapiens OX=9606 GN=RPL23 PE=1 SV=1 9.73 1769.4 - 1.25E+06 - - - -0.0989 - 0.931 0.068 - 113 2 2 0 -0.0001 8 0 0 0 2.16E+09 2.08E+09 - - - -0.8069 0.9996 221125_WJC_METTL3_EV_vs_WT_F03.06125.06125.2 0.00119 14-Aug K.LLESEEC[160.03]R.M "sp|Q3SY84|K2C71_HUMAN,sp|Q14CN4|K2C72_HUMAN" 2 1034.4703 0.12 24886 6125 2 1034.471016 518.2424 "Keratin, type II cytoskeletal 71 OS=Homo sapiens OX=9606 GN=KRT71 PE=1 SV=3" 4.25 1769.5 - 1.22E+06 - - - 0.7308 - 1.41 0.449 - 151.5 1 2 0 0.0008 8 0 0 0 1.33E+07 1.09E+08 - - - 3.3933 0.9994 221125_WJC_METTL3_EV_vs_WT_F03.06126.06126.2 0.00268 16-Aug R.YLTAEETDK.L sp|Q9HCD5|NCOA5_HUMAN 1 1068.4975 1.89 24887 6126 2 1068.495305 535.256 Nuclear receptor coactivator 5 OS=Homo sapiens OX=9606 GN=NCOA5 PE=1 SV=2 4.14 1769.7 - 271770 - - - -2.073 - 1.564 0.473 - 187.3 1 2 0 -0.0022 9 0 0 0 1.38E+08 7.34E+07 - - - 3.8278 0.9994 221125_WJC_METTL3_EV_vs_WT_F03.06129.06129.2 0.00709 16-Jul R.YLTAEETDK[136.11].L sp|Q9HCD5|NCOA5_HUMAN 1 1076.5117 1.89 24888 6129 2 1076.513218 539.2631 Nuclear receptor coactivator 5 OS=Homo sapiens OX=9606 GN=NCOA5 PE=1 SV=2 4.14 1770 - 423658 - - - 1.3915 - 1.494 0.426 - 129 1 2 0 0.0015 9 0 0 0 1.38E+08 7.34E+07 - - - 3.3484 0.9948 221125_WJC_METTL3_EV_vs_WT_F03.06156.06156.2 0.639 12-Aug R.LAELQAK[136.11].H "sp|O14737|PDCD5_HUMAN,sp|Q6ZRR7|LRRC9_HUMAN,tr|A0A2R8Y4H4|A0A2R8Y4H4_HUMAN,tr|H3BUB1|H3BUB1_HUMAN,tr|Q3HM38|Q3HM38_HUMAN,tr|A0A2R8YDI6|A0A2R8YDI6_HUMAN,tr|X6R2P6|X6R2P6_HUMAN,tr|K7ESJ4|K7ESJ4_HUMAN" 8 779.4633 0.99 24897 6156 2 779.463243 390.7389 Programmed cell death protein 5 OS=Homo sapiens OX=9606 GN=PDCD5 PE=1 SV=3 6 1773.7 - 2.62E+06 - - - -0.0141 - 1.723 0.041 - 173.1 1 2 0 0 7 0 0 0 1.31E+08 1.33E+08 - - - 1.0677 0.9986 221125_WJC_METTL3_EV_vs_WT_F03.06159.06159.2 0.466 14-Jul K.VHPAVVIR[166.11].Q "sp|P62829|RL23_HUMAN,tr|J3QQT9|J3QQT9_HUMAN,tr|J3KT29|J3KT29_HUMAN,tr|J3KTJ3|J3KTJ3_HUMAN,tr|C9JD32|C9JD32_HUMAN" 5 899.558 1.04 24898 6159 2 899.558265 450.7863 60S ribosomal protein L23 OS=Homo sapiens OX=9606 GN=RPL23 PE=1 SV=1 9.73 1774.1 - 7.19E+06 - - - 0.249 - 1.199 0.344 - 219.1 1 2 0 0.0002 8 0 0 0 2.16E+09 2.08E+09 - - - 2.1291 0.9983 221125_WJC_METTL3_EV_vs_WT_F03.06170.06170.2 0.316 14-Aug R.GPGPLQER[166.11].S "sp|P43243|MATR3_HUMAN,tr|A8MXP9|A8MXP9_HUMAN,tr|D6R991|D6R991_HUMAN,tr|A0A0R4J2E8|A0A0R4J2E8_HUMAN,tr|H0Y8T4|H0Y8T4_HUMAN,tr|D6REM6|D6REM6_HUMAN" 6 862.4536 1.38 24902 6170 2 862.453666 432.2341 Matrin-3 OS=Homo sapiens OX=9606 GN=MATR3 PE=1 SV=2 6 1775.6 - 3.49E+07 - - - 0.0348 - 1.552 0.212 - 290.5 1 2 0 0 8 0 0 0 1.01E+10 7.32E+09 - - - 1.9325 0.9992 221125_WJC_METTL3_EV_vs_WT_F03.06184.06184.2 0.0188 12-Jul R.QAAYEMR.M sp|Q9H0D6|XRN2_HUMAN 1 867.3909 0.96 24911 6184 2 867.391509 434.7027 5'-3' exoribonuclease 2 OS=Homo sapiens OX=9606 GN=XRN2 PE=1 SV=1 6 1777.2 - 2.89E+06 - - - 0.7171 - 1.369 0.359 - 297.2 1 2 0 0.0006 7 0 0 0 2.00E+08 2.08E+08 - - - 2.6876 0.9651 221125_WJC_METTL3_EV_vs_WT_F03.06186.06186.2 9.04 14-Jun K.ELGNSLDK.C "sp|Q8WWY3|PRP31_HUMAN,tr|E7EVX8|E7EVX8_HUMAN,tr|E7EU94|E7EU94_HUMAN,tr|E7ESX0|E7ESX0_HUMAN,tr|E7EN72|E7EN72_HUMAN" 5 874.4396 1.14 24912 6186 2 874.440622 438.2271 U4\U6 small nuclear ribonucleoprotein Prp31 OS=Homo sapiens OX=9606 GN=PRPF31 PE=1 SV=2 4.37 1777.4 - 7.50E+06 - - - 1.155 - 1.282 0.06 - 127.6 3 2 0 0.001 8 0 0 0 4.80E+08 4.22E+08 - - - 0.0199 0.9981 221125_WJC_METTL3_EV_vs_WT_F03.06192.06192.2 0.0526 14-Jun K.LLEGEETR[166.11].F "sp|Q16352|AINX_HUMAN,sp|P07197|NFM_HUMAN,sp|P07196|NFL_HUMAN,tr|E7ESP9|E7ESP9_HUMAN,tr|E7EMV2|E7EMV2_HUMAN" 5 955.485 2.21 24914 6192 2 955.483325 478.7498 Alpha-internexin OS=Homo sapiens OX=9606 GN=INA PE=1 SV=2 4.25 1778.2 - 633504 - - - -1.7478 - 1.296 0.341 - 95 1 2 0 -0.0017 8 0 0 0 6.79E+08 3.07E+08 - - - 2.3411 0.9977 221125_WJC_METTL3_EV_vs_WT_F03.06199.06199.2 0.103 14-Jul K.ALVATPGK[136.11].K "sp|P19338|NUCL_HUMAN,tr|A0A7I2V506|A0A7I2V506_HUMAN,tr|A0A7I2V699|A0A7I2V699_HUMAN,tr|A0A7I2V2U7|A0A7I2V2U7_HUMAN,tr|A0A7I2V3F3|A0A7I2V3F3_HUMAN,tr|A0A7I2V428|A0A7I2V428_HUMAN,tr|A0A7I2V349|A0A7I2V349_HUMAN,tr|H7BY16|H7BY16_HUMAN,tr|A0A7I2V5M5|A0A7I2V5M5_HUMAN,tr|A0A7I2V2S8|A0A7I2V2S8_HUMAN,tr|C9JLB1|C9JLB1_HUMAN" 11 763.4683 0.001 24918 6199 2 763.46762 382.7414 Nucleolin OS=Homo sapiens OX=9606 GN=NCL PE=1 SV=3 8.8 1779 - 3.98E+06 - - - -0.9418 - 1.477 0.215 - 219.1 1 2 0 -0.0007 8 0 0 0 0.00E+00 5.10E+08 - - - 1.805 0.9991 221125_WJC_METTL3_EV_vs_WT_F03.06201.06201.2 0.0607 14-Jul K.LLEGEETR.F "sp|Q16352|AINX_HUMAN,sp|P07197|NFM_HUMAN,sp|P07196|NFL_HUMAN,tr|E7ESP9|E7ESP9_HUMAN,tr|E7EMV2|E7EMV2_HUMAN" 5 945.4767 2.22 24920 6201 2 945.476325 473.7456 Alpha-internexin OS=Homo sapiens OX=9606 GN=INA PE=1 SV=2 4.25 1779.1 - 1.97E+06 - - - -0.4231 - 1.431 0.321 - 167.2 1 2 0 -0.0004 8 0 0 0 6.83E+08 3.07E+08 - - - 2.4926 0.9995 221125_WJC_METTL3_EV_vs_WT_F03.06250.06250.2 0.0055 16-Oct K.LVAAGSYQR.F "sp|Q6P1K2|PMF1_HUMAN,tr|U3KQ54|U3KQ54_HUMAN" 2 963.5138 1.86 24936 6250 2 963.513274 482.7642 Polyamine-modulated factor 1 OS=Homo sapiens OX=9606 GN=PMF1 PE=1 SV=2 8.75 1786 - 1.19E+06 - - - -0.5252 - 1.611 0.351 - 282.7 1 2 0 -0.0005 9 0 0 0 3.77E+07 2.02E+07 - - - 3.0129 0.9987 221125_WJC_METTL3_EV_vs_WT_F03.06260.06260.2 0.024 14-Jun K.ATVLTTER.K "sp|Q9UMS4|PRP19_HUMAN,tr|H0YGF3|H0YGF3_HUMAN,tr|F5GY56|F5GY56_HUMAN,tr|F5H2I0|F5H2I0_HUMAN" 4 889.4869 1.16 24938 6260 2 889.487446 445.7507 Pre-mRNA-processing factor 19 OS=Homo sapiens OX=9606 GN=PRPF19 PE=1 SV=1 6.05 1787.5 - 2.80E+07 - - - 0.6183 - 1.316 0.326 - 180.7 1 2 0 0.0006 8 0 0 0 1.85E+09 1.60E+09 - - - 2.2768 0.9987 221125_WJC_METTL3_EV_vs_WT_F03.06261.06261.2 0.011 14-Jul K.ATVLTTER[166.11].K "sp|Q9UMS4|PRP19_HUMAN,tr|H0YGF3|H0YGF3_HUMAN,tr|F5GY56|F5GY56_HUMAN,tr|F5H2I0|F5H2I0_HUMAN" 4 899.4952 1.13 24939 6261 2 899.495393 450.7549 Pre-mRNA-processing factor 19 OS=Homo sapiens OX=9606 GN=PRPF19 PE=1 SV=1 6.05 1787.5 - 2.67E+07 - - - 0.2524 - 1.476 0.268 - 261.5 1 2 0 0.0002 8 0 0 0 1.87E+09 1.66E+09 - - - 2.1946 1 221125_WJC_METTL3_EV_vs_WT_F03.06262.06262.2 2.84E-06 13/20 K.AAAAAAALQAK[136.11].S "sp|P36578|RL4_HUMAN,tr|H3BM89|H3BM89_HUMAN,tr|H3BU31|H3BU31_HUMAN" 3 963.5593 1.08 24940 6262 2 963.558295 482.7869 60S ribosomal protein L4 OS=Homo sapiens OX=9606 GN=RPL4 PE=1 SV=5 8.8 1787.6 - 1.34E+06 - - - -1.0223 - 2.465 0.575 - 720 1 2 0 -0.001 11 0 0 0 1.32E+08 1.23E+08 - - - 5.7283 0.9997 221125_WJC_METTL3_EV_vs_WT_F03.06263.06263.2 0.000488 20-Oct R.YISAAPGAEAK.Y "sp|Q8TB72|PUM2_HUMAN,sp|Q14671|PUM1_HUMAN,tr|Q5T1Z8|Q5T1Z8_HUMAN,tr|H0YDK8|H0YDK8_HUMAN,tr|A0A0C4DG68|A0A0C4DG68_HUMAN,tr|H0YEH2|H0YEH2_HUMAN,tr|Q5T1Z4|Q5T1Z4_HUMAN,tr|E9PR38|E9PR38_HUMAN" 8 1076.5502 1.97 24941 6263 2 1076.550263 539.2824 Pumilio homolog 2 OS=Homo sapiens OX=9606 GN=PUM2 PE=1 SV=2 6 1787.7 - 533758 - - - 0.0353 - 1.558 0.436 - 214.2 1 2 0 0 11 0 0 0 6.08E+08 3.09E+08 - - - 3.4608 1 221125_WJC_METTL3_EV_vs_WT_F03.06274.06274.2 5.46E-06 20-Dec K.AAAAAAALQAK.S "sp|P36578|RL4_HUMAN,tr|H3BM89|H3BM89_HUMAN,tr|H3BU31|H3BU31_HUMAN" 3 955.5451 1.08 24944 6274 2 955.543794 478.7798 60S ribosomal protein L4 OS=Homo sapiens OX=9606 GN=RPL4 PE=1 SV=5 8.8 1789.2 - 2.65E+06 - - - -1.3458 - 2.412 0.588 - 447.9 1 2 0 -0.0013 11 0 0 0 1.32E+08 1.23E+08 - - - 5.7654 0.9362 221125_WJC_METTL3_EV_vs_WT_F03.06278.06278.2 2.49 12-Jun R.LPPEVNR.L sp|Q9Y3B4|SF3B6_HUMAN 1 823.4552 1.21 24945 6278 2 823.453984 412.7349 Splicing factor 3B subunit 6 OS=Homo sapiens OX=9606 GN=SF3B6 PE=1 SV=1 6 1789.8 - 2.47E+06 - - - -1.4791 - 1.188 0.011 - 123.4 1 2 0 -0.0012 7 0 0 0 1.70E+08 1.41E+08 - - - -0.3323 0.9834 221125_WJC_METTL3_EV_vs_WT_F03.06286.06286.2 0.942 12-Jun R.EAVTLSR[166.11].D sp|Q8N4Q0|PTGR3_HUMAN 1 784.4318 0.89 24950 6286 2 784.430256 393.2232 Prostaglandin reductase 3 OS=Homo sapiens OX=9606 GN=ZADH2 PE=1 SV=1 6.1 1790.8 - 2.71E+06 - - - -2.0167 - 1.261 0.157 - 106.4 2 2 0 -0.0016 7 0 0 0 1.49E+08 1.67E+08 - - - 0.8004 0.9661 221125_WJC_METTL3_EV_vs_WT_F03.06288.06288.2 4.01 14-Jun K.SIQSGPLK.L "sp|Q16891|MIC60_HUMAN,tr|B9A067|B9A067_HUMAN,tr|A0A087WYS0|A0A087WYS0_HUMAN,tr|D6RAW4|D6RAW4_HUMAN,tr|C9J406|C9J406_HUMAN" 5 828.4705 0.81 24951 6288 2 828.471873 415.2425 MICOS complex subunit MIC60 OS=Homo sapiens OX=9606 GN=IMMT PE=1 SV=1 8.47 1791 - 2.02E+06 - - - 1.6355 - 1.172 0.093 - 81.5 1 2 0 0.0014 8 0 0 0 5.42E+08 6.65E+08 - - - 0.2061 0.9995 221125_WJC_METTL3_EV_vs_WT_F03.06292.06292.2 0.0219 14-Aug K.LLEGEEER[166.11].L "sp|P02545|LMNA_HUMAN,sp|P20700|LMNB1_HUMAN,sp|Q03252|LMNB2_HUMAN,tr|A0A804HL68|A0A804HL68_HUMAN,tr|Q5TCI8|Q5TCI8_HUMAN,tr|A0A6Q8PFJ0|A0A6Q8PFJ0_HUMAN,tr|A0A6Q8PHQ9|A0A6Q8PHQ9_HUMAN,tr|E9PBF6|E9PBF6_HUMAN,tr|Q3BDU5|Q3BDU5_HUMAN" 9 983.4799 1.36 24954 6292 2 983.478637 492.7472 Prelamin-A\C OS=Homo sapiens OX=9606 GN=LMNA PE=1 SV=1 4.09 1791.4 - 4.67E+06 - - - -1.2944 - 1.718 0.356 - 218.4 1 2 0 -0.0013 8 0 0 0 7.28E+08 5.37E+08 - - - 3.3021 0.9942 221125_WJC_METTL3_EV_vs_WT_F03.06295.06295.2 0.00856 15/24 R.PAAAAAAATPAVR.T "sp|P11940|PABP1_HUMAN,tr|H0YAS6|H0YAS6_HUMAN,tr|H0YB75|H0YB75_HUMAN,tr|H0YAS7|H0YAS7_HUMAN,tr|A0A7I2YQE4|A0A7I2YQE4_HUMAN,tr|H0YAW6|H0YAW6_HUMAN,tr|A0A7I2V649|A0A7I2V649_HUMAN,tr|H0YAR2|H0YAR2_HUMAN,tr|E7ERJ7|E7ERJ7_HUMAN,tr|A0A7I2YQ88|A0A7I2YQ88_HUMAN,tr|A0A087WTT1|A0A087WTT1_HUMAN,tr|A0A7I2YQ90|A0A7I2YQ90_HUMAN,tr|A0A7I2V4N4|A0A7I2V4N4_HUMAN,tr|E7EQV3|E7EQV3_HUMAN" 14 1136.6302 2.17 24955 6295 2 1136.6309 569.3224 Polyadenylate-binding protein 1 OS=Homo sapiens OX=9606 GN=PABPC1 PE=1 SV=2 10.18 1791.8 - 298798 - - - 0.6106 - 2.841 0.522 - 923.5 1 1 0 0.0007 13 0 0 0 6.35E+07 2.92E+07 - - - 5.5761 0.9986 221125_WJC_METTL3_EV_vs_WT_F03.06304.06304.2 0.189 14-Jul R.GPGPLQER.S "sp|P43243|MATR3_HUMAN,tr|A8MXP9|A8MXP9_HUMAN,tr|D6R991|D6R991_HUMAN,tr|A0A0R4J2E8|A0A0R4J2E8_HUMAN,tr|H0Y8T4|H0Y8T4_HUMAN,tr|D6REM6|D6REM6_HUMAN" 6 852.4454 1.45 24960 6304 2 852.444118 427.23 Matrin-3 OS=Homo sapiens OX=9606 GN=MATR3 PE=1 SV=2 6 1792.8 - 2.04E+07 - - - -1.464 - 1.611 0.27 - 194.5 1 2 0 -0.0012 8 0 0 0 3.55E+09 2.45E+09 - - - 2.473 0.9992 221125_WJC_METTL3_EV_vs_WT_F03.06309.06309.2 0.00139 16-Jun R.VFNTGGAPR[166.11].L "sp|P27708|PYR1_HUMAN,tr|F8VPD4|F8VPD4_HUMAN" 2 927.4802 1.21 24963 6309 2 927.481062 464.7474 CAD protein OS=Homo sapiens OX=9606 GN=CAD PE=1 SV=3 9.72 1793.4 - 600691 - - - 0.9456 - 1.409 0.384 - 85.7 1 2 0 0.0009 9 0 0 0 6.28E+07 5.19E+07 - - - 2.8689 0.996 221125_WJC_METTL3_EV_vs_WT_F03.06312.06312.2 0.0708 14-Jul R.VVAVSSVR.L sp|Q96H79|ZCCHL_HUMAN 1 815.4865 0.6 24964 6312 2 815.486045 408.7505 Zinc finger CCCH-type antiviral protein 1-like OS=Homo sapiens OX=9606 GN=ZC3HAV1L PE=1 SV=2 9.72 1793.8 - 2.32E+06 - - - -0.5604 - 1.282 0.203 - 154.2 1 2 0 -0.0005 8 0 0 0 1.28E+08 2.13E+08 - - - 1.2894 0.9983 221125_WJC_METTL3_EV_vs_WT_F03.06332.06332.2 0.0815 14-Aug K.LLEGEEER.L "sp|P02545|LMNA_HUMAN,sp|P20700|LMNB1_HUMAN,sp|Q03252|LMNB2_HUMAN,tr|A0A804HL68|A0A804HL68_HUMAN,tr|Q5TCI8|Q5TCI8_HUMAN,tr|A0A6Q8PFJ0|A0A6Q8PFJ0_HUMAN,tr|A0A6Q8PHQ9|A0A6Q8PHQ9_HUMAN,tr|E9PBF6|E9PBF6_HUMAN,tr|Q3BDU5|Q3BDU5_HUMAN" 9 973.4716 1.36 24971 6332 2 973.471911 487.7431 Prelamin-A\C OS=Homo sapiens OX=9606 GN=LMNA PE=1 SV=1 4.09 1796.4 - 1.98E+07 - - - 0.2784 - 1.356 0.268 - 208.6 1 2 0 0.0003 8 0 0 0 7.29E+08 5.37E+08 - - - 1.9388 0.7995 221125_WJC_METTL3_EV_vs_WT_F03.06334.06334.2 2.87 22-Jun R.DVTADFEGQSPK.C sp|Q9UHL4|DPP2_HUMAN 1 1292.5885 47.42 24972 6334 2 1292.591364 647.3015 Dipeptidyl peptidase 2 OS=Homo sapiens OX=9606 GN=DPP7 PE=1 SV=3 4.03 1796.6 - 247339 - - - 2.2459 - 0.97 0.035 - 61.8 1 2 0 0.0029 12 0 0 0 6.60E+07 1.39E+06 - - - -0.7815 0.9929 221125_WJC_METTL3_EV_vs_WT_F03.06340.06340.2 0.248 14-Jul R.TC[160.03]GEVIVK.G sp|Q9Y2X9|ZN281_HUMAN 1 904.4688 1.32 24974 6340 2 904.468498 453.2417 Zinc finger protein 281 OS=Homo sapiens OX=9606 GN=ZNF281 PE=1 SV=1 5.66 1797.4 - 1.90E+06 - - - -0.3383 - 1.242 0.157 - 209.1 1 2 0 -0.0003 8 0 0 0 9.32E+07 7.04E+07 - - - 0.8541 0.9999 221125_WJC_METTL3_EV_vs_WT_F03.06342.06342.2 0.00069 16-Nov R.VTDALNATR[166.11].A "sp|P10809|CH60_HUMAN,tr|A0A7I2V2X6|A0A7I2V2X6_HUMAN,tr|A0A7I2YQK6|A0A7I2YQK6_HUMAN,tr|A0A7I2V599|A0A7I2V599_HUMAN" 4 969.5119 1.29 24976 6342 2 969.512057 485.7632 "60 kDa heat shock protein, mitochondrial OS=Homo sapiens OX=9606 GN=HSPD1 PE=1 SV=2" 5.81 1797.6 - 1.70E+07 - - - 0.1836 - 2.401 0.483 - 473.7 1 2 0 0.0002 9 0 0 0 3.22E+09 2.50E+09 - - - 5.1424 0.9996 221125_WJC_METTL3_EV_vs_WT_F03.06353.06353.2 5.52E-05 14-Nov R.TC[160.03]GEVIVK[136.11].G sp|Q9Y2X9|ZN281_HUMAN 1 912.483 1.32 24980 6353 2 912.480969 457.2488 Zinc finger protein 281 OS=Homo sapiens OX=9606 GN=ZNF281 PE=1 SV=1 5.66 1799.1 - 2.08E+06 - - - -2.2302 - 1.935 0.451 - 479.3 1 2 0 -0.002 8 0 0 0 9.33E+07 7.04E+07 - - - 4.3623 0.9978 221125_WJC_METTL3_EV_vs_WT_F03.06354.06354.2 0.189 14-Jun K.VHPAVVIR.Q "sp|P62829|RL23_HUMAN,tr|J3QQT9|J3QQT9_HUMAN,tr|J3KT29|J3KT29_HUMAN,tr|J3KTJ3|J3KTJ3_HUMAN,tr|C9JD32|C9JD32_HUMAN" 5 889.5498 1.04 24981 6354 2 889.548981 445.7822 60S ribosomal protein L23 OS=Homo sapiens OX=9606 GN=RPL23 PE=1 SV=1 9.73 1799.2 - 1.03E+06 - - - -0.8881 - 1.149 0.321 - 118.9 1 2 0 -0.0008 8 0 0 0 2.16E+09 2.07E+09 - - - 1.8305 0.9946 221125_WJC_METTL3_EV_vs_WT_F03.06359.06359.2 0.157 12-May K.TTIIEGR.L "sp|Q9NVS2|RT18A_HUMAN,tr|Q5QPA5|Q5QPA5_HUMAN" 2 788.4392 0.65 24983 6359 2 788.439498 395.2269 "39S ribosomal protein S18a, mitochondrial OS=Homo sapiens OX=9606 GN=MRPS18A PE=1 SV=1" 5.66 1799.8 - 1.95E+06 - - - 0.3551 - 1.351 0.166 - 73.1 2 2 0 0.0003 7 0 0 0 6.12E+07 9.40E+07 - - - 1.0858 0.9968 221125_WJC_METTL3_EV_vs_WT_F03.06363.06363.2 0.318 14-Jul K.VVTVVTTK.K "sp|Q7L014|DDX46_HUMAN,tr|D6RJA6|D6RJA6_HUMAN,tr|A0A0C4DG89|A0A0C4DG89_HUMAN" 3 845.5222 1.13 24985 6363 2 845.52117 423.7684 Probable ATP-dependent RNA helicase DDX46 OS=Homo sapiens OX=9606 GN=DDX46 PE=1 SV=2 8.72 1800.4 - 1.78E+06 - - - -1.2407 - 1.425 0.209 - 158.9 1 2 0 -0.001 8 0 0 0 7.35E+07 6.49E+07 - - - 1.6525 0.9992 221125_WJC_METTL3_EV_vs_WT_F03.06368.06368.2 0.0245 12-Jun R.NC[160.03]AAYLK[136.11].L "sp|Q7Z406|MYH14_HUMAN,sp|P35580|MYH10_HUMAN,sp|P35749|MYH11_HUMAN,sp|P35579|MYH9_HUMAN,tr|M0QY43|M0QY43_HUMAN" 5 846.4149 0.87 24989 6368 2 846.414529 424.2147 Myosin-14 OS=Homo sapiens OX=9606 GN=MYH14 PE=1 SV=2 8.2 1800.8 - 1.95E+06 - - - -0.4667 - 1.192 0.402 - 136 1 2 0 -0.0004 7 0 0 0 8.68E+07 9.92E+07 - - - 2.5665 0.9443 221125_WJC_METTL3_EV_vs_WT_F03.06369.06369.2 2.78 12-Jul K.MSLEQAK.A "sp|O43148|MCES_HUMAN,tr|K7EPP5|K7EPP5_HUMAN" 2 805.4004 1.26 24990 6369 2 805.397841 403.7075 mRNA cap guanine-N7 methyltransferase OS=Homo sapiens OX=9606 GN=RNMT PE=1 SV=1 5.75 1800.8 - 1.49E+06 - - - -3.1636 - 1.123 0.151 - 179.7 1 2 0 -0.0025 7 0 0 0 8.29E+07 6.58E+07 - - - 0.5231 0.9991 221125_WJC_METTL3_EV_vs_WT_F03.06378.06378.2 0.0578 14-Aug K.VEESPLEK.V "sp|Q8IWC1|MA7D3_HUMAN,tr|A0A0A0MRP0|A0A0A0MRP0_HUMAN" 2 929.4706 2.31 24993 6378 2 929.471053 465.7426 MAP7 domain-containing protein 3 OS=Homo sapiens OX=9606 GN=MAP7D3 PE=1 SV=2 4.25 1802 - 1.04E+06 - - - 0.5121 - 1.608 0.285 - 183.3 1 2 0 0.0005 8 0 0 0 1.41E+08 6.12E+07 - - - 2.5784 0.9954 221125_WJC_METTL3_EV_vs_WT_F03.06398.06398.2 0.0864 18-Jun R.LLGTAGTEEK.K sp|Q9UEU0|VTI1B_HUMAN 1 1017.5342 1.22 25003 6398 2 1017.532682 509.7744 Vesicle transport through interaction with t-SNAREs homolog 1B OS=Homo sapiens OX=9606 GN=VTI1B PE=1 SV=3 4.53 1804.3 - 305699 - - - -1.5312 - 1.243 0.279 - 63.4 3 2 0 -0.0016 10 0 0 0 2.69E+07 2.21E+07 - - - 1.4953 0.9899 221125_WJC_METTL3_EV_vs_WT_F03.06404.06404.2 1.96 14-Apr K.EMGTPGYR.G sp|Q6DKI1|RL7L_HUMAN 1 909.4015 0.96 25007 6404 2 909.401544 455.708 60S ribosomal protein L7-like 1 OS=Homo sapiens OX=9606 GN=RPL7L1 PE=1 SV=2 6.1 1805.1 - 309463 - - - 0.1012 - 0.894 0.259 - 45.5 1 2 0 0.0001 8 0 0 0 1.72E+07 1.79E+07 - - - 0.616 0.9985 221125_WJC_METTL3_EV_vs_WT_F03.06405.06405.2 0.0575 18-Aug R.LLGTAGTEEK[136.11].K sp|Q9UEU0|VTI1B_HUMAN 1 1025.5484 1.22 25008 6405 2 1025.547388 513.7815 Vesicle transport through interaction with t-SNAREs homolog 1B OS=Homo sapiens OX=9606 GN=VTI1B PE=1 SV=3 4.53 1805.2 - 494757 - - - -1.0258 - 1.604 0.246 - 106.4 1 2 0 -0.0011 10 0 0 0 2.69E+07 2.21E+07 - - - 2.1765 0.9909 221125_WJC_METTL3_EV_vs_WT_F03.06408.06408.2 0.227 14-Aug K.LEQSTIVK.E sp|Q02790|FKBP4_HUMAN 1 916.5229 2.33 25009 6408 2 916.519916 459.2687 Peptidyl-prolyl cis-trans isomerase FKBP4 OS=Homo sapiens OX=9606 GN=FKBP4 PE=1 SV=3 6 1805.6 - 762646 - - - -3.3071 - 1.497 0.23 - 216.3 1 2 0 -0.003 8 0 0 0 4.41E+07 1.89E+07 - - - 1.9557 0.9978 221125_WJC_METTL3_EV_vs_WT_F03.06410.06410.2 0.281 14-Aug R.GPGPLQER[166.11].S "sp|P43243|MATR3_HUMAN,tr|A8MXP9|A8MXP9_HUMAN,tr|D6R991|D6R991_HUMAN,tr|A0A0R4J2E8|A0A0R4J2E8_HUMAN,tr|H0Y8T4|H0Y8T4_HUMAN,tr|D6REM6|D6REM6_HUMAN" 6 862.4536 1.47 25010 6410 2 862.452698 432.2341 Matrin-3 OS=Homo sapiens OX=9606 GN=MATR3 PE=1 SV=2 6 1805.8 - 4.30E+06 - - - -1.0876 - 1.597 0.193 - 294.8 1 2 0 -0.0009 8 0 0 0 3.56E+09 2.42E+09 - - - 1.8781 0.9998 221125_WJC_METTL3_EV_vs_WT_F03.06412.06412.2 2.22E-05 12-Jul R.C[160.03]GSVLVR[166.11].L "sp|P15880|RS2_HUMAN,tr|I3L404|I3L404_HUMAN,tr|E9PM36|E9PM36_HUMAN,tr|E9PQD7|E9PQD7_HUMAN,tr|E9PMM9|E9PMM9_HUMAN,tr|H0YEN5|H0YEN5_HUMAN" 6 799.425 1.22 25011 6412 2 799.424641 400.7198 40S ribosomal protein S2 OS=Homo sapiens OX=9606 GN=RPS2 PE=1 SV=2 8.25 1806.1 - 2.29E+07 - - - -0.4216 - 1.628 0.496 - 232.9 1 2 0 -0.0003 7 0 0 0 9.08E+08 7.45E+08 - - - 4.2486 0.9996 221125_WJC_METTL3_EV_vs_WT_F03.06431.06431.2 0.000924 16-Oct R.VTDALNATR.A "sp|P10809|CH60_HUMAN,tr|A0A7I2V2X6|A0A7I2V2X6_HUMAN,tr|A0A7I2YQK6|A0A7I2YQK6_HUMAN,tr|A0A7I2V599|A0A7I2V599_HUMAN" 4 959.5036 1.29 25018 6431 2 959.501934 480.7591 "60 kDa heat shock protein, mitochondrial OS=Homo sapiens OX=9606 GN=HSPD1 PE=1 SV=2" 5.81 1808.4 - 9.18E+06 - - - -1.7457 - 2.022 0.381 - 398.9 1 2 0 -0.0017 9 0 0 0 3.22E+09 2.50E+09 - - - 3.8915 0.9891 221125_WJC_METTL3_EV_vs_WT_F03.06436.06436.2 0.307 18-Aug R.LLEAAAQSTK.G "sp|Q15149|PLEC_HUMAN,tr|H0YDN1|H0YDN1_HUMAN" 2 1030.5659 1.68 25020 6436 2 1030.568084 516.2902 Plectin OS=Homo sapiens OX=9606 GN=PLEC PE=1 SV=3 6 1809 - 449433 - - - 2.1435 - 1.301 0.194 - 117 1 2 0 0.0022 10 0 0 0 1.40E+08 8.29E+07 - - - 1.2077 0.9992 221125_WJC_METTL3_EV_vs_WT_F03.06440.06440.2 0.129 14-Aug K.IVNLGSSK.T sp|Q7RTV0|PHF5A_HUMAN 1 816.4705 0.99 25022 6440 2 816.469803 409.2425 PHD finger-like domain-containing protein 5A OS=Homo sapiens OX=9606 GN=PHF5A PE=1 SV=1 8.75 1809.5 - 5.09E+06 - - - -0.8757 - 1.818 0.254 - 135.7 1 2 0 -0.0007 8 0 0 0 2.54E+08 2.57E+08 - - - 2.7196 0.9842 221125_WJC_METTL3_EV_vs_WT_F03.06445.06445.2 0.0751 14-Sep K.VTASPLQR[166.11].L "sp|Q9NUI1|DECR2_HUMAN,tr|Q4VXZ8|Q4VXZ8_HUMAN" 2 880.5006 1.61 25025 6445 2 880.504502 441.2576 "Peroxisomal 2,4-dienoyl-CoA reductase [(3E)-enoyl-CoA-producing] OS=Homo sapiens OX=9606 GN=DECR2 PE=1 SV=1" 9.72 1810 - 915327 - - - 4.4475 - 1.681 0.217 - 284.8 1 2 0 0.0039 8 0 0 0 6.89E+07 4.27E+07 - - - 2.209 0.9982 221125_WJC_METTL3_EV_vs_WT_F03.06446.06446.2 0.0235 14-Sep K.IVNLGSSK[136.11].T sp|Q7RTV0|PHF5A_HUMAN 1 824.4847 1.02 25026 6446 2 824.483515 413.2496 PHD finger-like domain-containing protein 5A OS=Homo sapiens OX=9606 GN=PHF5A PE=1 SV=1 8.75 1810 - 5.35E+06 - - - -1.4591 - 1.563 0.25 - 202.1 1 2 0 -0.0012 8 0 0 0 2.64E+08 2.59E+08 - - - 2.2341 0.9479 221125_WJC_METTL3_EV_vs_WT_F03.06449.06449.2 0.803 14-Jun R.NGLGAPVR.L "sp|Q14671|PUM1_HUMAN,tr|Q5T1Z8|Q5T1Z8_HUMAN,tr|H0YDK8|H0YDK8_HUMAN,tr|H0YEH2|H0YEH2_HUMAN,tr|Q5T1Z4|Q5T1Z4_HUMAN,tr|E9PR38|E9PR38_HUMAN" 6 782.4399 2.29 25027 6449 2 782.437331 392.2272 Pumilio homolog 1 OS=Homo sapiens OX=9606 GN=PUM1 PE=1 SV=3 9.75 1810.4 - 5.68E+06 - - - -3.2654 - 1.399 0.095 - 95.5 2 2 0 -0.0026 8 0 0 0 2.27E+08 9.91E+07 - - - 0.62 0.9894 221125_WJC_METTL3_EV_vs_WT_F03.06450.06450.2 1.34 14-Jul K.IETAQELK[136.11].N "sp|Q9BVL2|NUP58_HUMAN,tr|H7BYF2|H7BYF2_HUMAN,tr|Q5JRG1|Q5JRG1_HUMAN" 3 938.5164 2.46 25028 6450 2 938.516445 470.2655 Nucleoporin p58\p45 OS=Homo sapiens OX=9606 GN=NUP58 PE=1 SV=1 4.53 1810.5 - 2.87E+06 - - - 0.0352 - 1.232 0.123 - 123.6 1 2 0 0 8 0 0 0 2.00E+08 8.13E+07 - - - 0.5787 0.8936 221125_WJC_METTL3_EV_vs_WT_F03.06451.06451.2 0.223 12-Jun K.LTELEQR[166.11].L "sp|O75179|ANR17_HUMAN,tr|H0YM23|H0YM23_HUMAN,tr|A0A1W2PQ15|A0A1W2PQ15_HUMAN,tr|H0YLQ3|H0YLQ3_HUMAN" 4 897.4795 3.18 25029 6451 2 897.476308 449.747 Ankyrin repeat domain-containing protein 17 OS=Homo sapiens OX=9606 GN=ANKRD17 PE=1 SV=3 4.53 1810.6 - 1.08E+06 - - - -3.5745 - 1.336 0.041 - 143.3 1 2 0 -0.0032 7 0 0 0 1.91E+08 6.00E+07 - - - 0.2607 0.9943 221125_WJC_METTL3_EV_vs_WT_F03.06456.06456.2 0.00655 18-Nov R.LLEAAAQSTK[136.11].G "sp|Q15149|PLEC_HUMAN,tr|H0YDN1|H0YDN1_HUMAN" 2 1038.5801 1.68 25031 6456 2 1038.574291 520.2973 Plectin OS=Homo sapiens OX=9606 GN=PLEC PE=1 SV=3 6 1811.2 - 1.17E+06 - - - -5.5691 - 2.172 0.392 - 340.8 1 2 0 -0.0058 10 0 0 0 1.40E+08 8.29E+07 - - - 4.0996 0.9863 221125_WJC_METTL3_EV_vs_WT_F03.06461.06461.2 0.0982 12-Jul R.MAAPIDR[166.11].V "sp|P52272|HNRPM_HUMAN,tr|M0R2I7|M0R2I7_HUMAN,tr|A0A087X0X3|A0A087X0X3_HUMAN,tr|M0QZM1|M0QZM1_HUMAN" 4 782.3984 1.6 25034 6461 2 782.396639 392.2065 Heterogeneous nuclear ribonucleoprotein M OS=Homo sapiens OX=9606 GN=HNRNPM PE=1 SV=3 5.59 1811.8 - 5.15E+06 - - - -2.2878 - 1.515 0.097 - 203 1 2 0 -0.0018 7 0 0 0 2.58E+09 1.61E+09 - - - 1.0731 0.9867 221125_WJC_METTL3_EV_vs_WT_F03.06462.06462.2 0.0819 14-Jun K.IIDPDEEK[136.11].A "sp|Q13356|PPIL2_HUMAN,tr|A0A7P0TBL3|A0A7P0TBL3_HUMAN,tr|A0A7P0TA15|A0A7P0TA15_HUMAN,tr|A0A7P0TAH4|A0A7P0TAH4_HUMAN,tr|A0A7P0TB19|A0A7P0TB19_HUMAN,tr|A0A7P0Z4K4|A0A7P0Z4K4_HUMAN,tr|A0A7P0T8E8|A0A7P0T8E8_HUMAN,tr|A0A7P0T843|A0A7P0T843_HUMAN,tr|A0A7P0T839|A0A7P0T839_HUMAN,tr|A0A7P0T896|A0A7P0T896_HUMAN" 10 965.4797 0.38 25035 6462 2 965.480665 483.7471 RING-type E3 ubiquitin-protein ligase PPIL2 OS=Homo sapiens OX=9606 GN=PPIL2 PE=1 SV=1 3.92 1811.9 - 986515 - - - 1.0078 - 1.286 0.129 - 88.4 2 2 0 0.001 8 0 0 0 3.71E+07 9.74E+07 - - - 0.6176 0.936 221125_WJC_METTL3_EV_vs_WT_F03.06463.06463.2 0.0126 12-Aug L.LEGEEC[160.03]R.M "sp|Q86Y46|K2C73_HUMAN,sp|Q7RTS7|K2C74_HUMAN,sp|P48668|K2C6C_HUMAN,sp|Q01546|K22O_HUMAN,sp|P12036|NFH_HUMAN,sp|Q8N1N4|K2C78_HUMAN,sp|P04259|K2C6B_HUMAN,sp|P13647|K2C5_HUMAN,sp|P35908|K22E_HUMAN,sp|O95678|K2C75_HUMAN,sp|P02538|K2C6A_HUMAN,tr|H0YI76|H0YI76_HUMAN,tr|H0YIC5|H0YIC5_HUMAN,tr|F8W1S1|F8W1S1_HUMAN" 14 891.3756 1.31 25036 6463 2 891.37365 446.6951 "Keratin, type II cytoskeletal 73 OS=Homo sapiens OX=9606 GN=KRT73 PE=1 SV=1" 4.25 1812 - 1.34E+06 - - - -2.2224 - 1.597 0.353 - 207.6 1 1 0 -0.002 7 0 0 0 4.84E+07 3.70E+07 - - - 3.1309 0.9995 221125_WJC_METTL3_EV_vs_WT_F03.06467.06467.2 0.0253 14-Sep K.TAVAPIER[166.11].V "sp|P12235|ADT1_HUMAN,sp|Q9H0C2|ADT4_HUMAN,sp|P05141|ADT2_HUMAN,sp|P12236|ADT3_HUMAN,tr|V9GYG0|V9GYG0_HUMAN" 5 865.4897 0.9 25038 6467 2 865.488839 433.7521 ADP\ATP translocase 1 OS=Homo sapiens OX=9606 GN=SLC25A4 PE=1 SV=4 5.66 1812.6 - 2.37E+06 - - - -0.9798 - 1.665 0.36 - 434 1 2 0 -0.0008 8 0 0 0 1.85E+09 2.05E+09 - - - 3.2373 0.9989 221125_WJC_METTL3_EV_vs_WT_F03.06474.06474.2 0.142 14-Aug K.TAVAPIER.V "sp|P12235|ADT1_HUMAN,sp|Q9H0C2|ADT4_HUMAN,sp|P05141|ADT2_HUMAN,sp|P12236|ADT3_HUMAN,tr|V9GYG0|V9GYG0_HUMAN" 5 855.4814 0.9 25040 6474 2 855.480166 428.748 ADP\ATP translocase 1 OS=Homo sapiens OX=9606 GN=SLC25A4 PE=1 SV=4 5.66 1813.5 - 2.82E+06 - - - -1.4623 - 1.667 0.278 - 345.9 1 2 0 -0.0013 8 0 0 0 1.85E+09 2.06E+09 - - - 2.6351 0.9987 221125_WJC_METTL3_EV_vs_WT_F03.06476.06476.2 0.0843 16-Aug K.VAASPEDIK[136.11].L "sp|Q92552|RT27_HUMAN,tr|G5EA06|G5EA06_HUMAN,tr|D6RH20|D6RH20_HUMAN" 3 936.5008 1.79 25041 6476 2 936.499278 469.2577 "28S ribosomal protein S27, mitochondrial OS=Homo sapiens OX=9606 GN=MRPS27 PE=1 SV=3" 4.37 1813.7 - 1.91E+06 - - - -1.5846 - 1.546 0.308 - 175.9 1 2 0 -0.0015 9 0 0 0 3.19E+08 1.78E+08 - - - 2.5758 0.9967 221125_WJC_METTL3_EV_vs_WT_F03.06485.06485.2 0.0134 14-Aug K.IIDPDEEK.A "sp|Q13356|PPIL2_HUMAN,tr|A0A7P0TBL3|A0A7P0TBL3_HUMAN,tr|A0A7P0TA15|A0A7P0TA15_HUMAN,tr|A0A7P0TAH4|A0A7P0TAH4_HUMAN,tr|A0A7P0TB19|A0A7P0TB19_HUMAN,tr|A0A7P0Z4K4|A0A7P0Z4K4_HUMAN,tr|A0A7P0T8E8|A0A7P0T8E8_HUMAN,tr|A0A7P0T843|A0A7P0T843_HUMAN,tr|A0A7P0T839|A0A7P0T839_HUMAN,tr|A0A7P0T896|A0A7P0T896_HUMAN" 10 957.4655 0.47 25044 6485 2 957.461851 479.74 RING-type E3 ubiquitin-protein ligase PPIL2 OS=Homo sapiens OX=9606 GN=PPIL2 PE=1 SV=1 3.92 1814.9 - 477034 - - - -3.8027 - 1.509 0.397 - 150.1 1 2 0 -0.0036 8 0 0 0 3.71E+07 7.96E+07 - - - 3.213 0.9988 221125_WJC_METTL3_EV_vs_WT_F03.06492.06492.2 0.00982 14-Jul K.ISDSEGFK.A sp|P23246|SFPQ_HUMAN 1 881.4131 0.8 25047 6492 2 881.41489 441.7138 "Splicing factor, proline- and glutamine-rich OS=Homo sapiens OX=9606 GN=SFPQ PE=1 SV=2" 4.37 1815.8 - 797972 - - - 2.0728 - 1.354 0.415 - 95.7 1 2 0 0.0018 8 0 0 0 1.70E+08 2.12E+08 - - - 3.0196 0.9772 221125_WJC_METTL3_EV_vs_WT_F03.06517.06517.2 2.38 12-Jul K.SLDEMEK.Q "sp|P23246|SFPQ_HUMAN,tr|H0Y9K7|H0Y9K7_HUMAN" 2 850.3742 0.84 25056 6517 2 850.374297 426.1944 "Splicing factor, proline- and glutamine-rich OS=Homo sapiens OX=9606 GN=SFPQ PE=1 SV=2" 4.14 1819.1 - 1.42E+06 - - - 0.0741 - 1.014 0.134 - 146.9 1 2 0 0.0001 7 0 0 0 2.37E+08 2.82E+08 - - - 0.0748 0.9974 221125_WJC_METTL3_EV_vs_WT_F03.06520.06520.2 0.0669 20-Oct R.VAAAPASGALR[166.11].R "sp|P06576|ATPB_HUMAN,tr|F8W079|F8W079_HUMAN,tr|F8W0P7|F8W0P7_HUMAN,tr|H0YH81|H0YH81_HUMAN" 4 992.5642 2.58 25057 6520 2 992.564606 497.2894 "ATP synthase subunit beta, mitochondrial OS=Homo sapiens OX=9606 GN=ATP5F1B PE=1 SV=3" 9.72 1819.5 - 561362 - - - 0.3597 - 1.964 0.102 - 427.5 1 2 0 0.0004 11 0 0 0 4.21E+08 1.63E+08 - - - 1.6202 0.8936 221125_WJC_METTL3_EV_vs_WT_F03.06522.06522.2 0.00268 14-Aug K.FASNVVEK.C "sp|Q8TB72|PUM2_HUMAN,sp|Q14671|PUM1_HUMAN,tr|Q5T1Z8|Q5T1Z8_HUMAN,tr|H0YDK8|H0YDK8_HUMAN,tr|H0YC97|H0YC97_HUMAN,tr|A0A0C4DG68|A0A0C4DG68_HUMAN,tr|H0YEH2|H0YEH2_HUMAN,tr|Q5T1Z4|Q5T1Z4_HUMAN,tr|H0YDC5|H0YDC5_HUMAN,tr|E9PR38|E9PR38_HUMAN" 10 892.4654 1.83 25058 6522 2 893.465447 447.24 Pumilio homolog 2 OS=Homo sapiens OX=9606 GN=PUM2 PE=1 SV=2 6 1819.7 - 5.70E+06 - - - 1120.5084 - 1.501 0.456 - 144 1 2 0 1 8 0 0 0 2.24E+09 1.23E+09 - - - 3.3199 0.9993 221125_WJC_METTL3_EV_vs_WT_F03.06523.06523.2 0.00508 20-Oct R.VAAAPASGALR.R "sp|P06576|ATPB_HUMAN,tr|F8W079|F8W079_HUMAN,tr|F8W0P7|F8W0P7_HUMAN,tr|H0YH81|H0YH81_HUMAN" 4 982.556 2.58 25059 6523 2 982.556656 492.2853 "ATP synthase subunit beta, mitochondrial OS=Homo sapiens OX=9606 GN=ATP5F1B PE=1 SV=3" 9.72 1819.8 - 1.09E+06 - - - 0.689 - 2.18 0.238 - 393.8 1 2 0 0.0007 11 0 0 0 4.21E+08 1.63E+08 - - - 2.9069 0.999 221125_WJC_METTL3_EV_vs_WT_F03.06524.06524.2 0.0233 14-Jun K.FASNVVEK[136.11].C "sp|Q8TB72|PUM2_HUMAN,sp|Q14671|PUM1_HUMAN,tr|Q5T1Z8|Q5T1Z8_HUMAN,tr|H0YDK8|H0YDK8_HUMAN,tr|H0YC97|H0YC97_HUMAN,tr|A0A0C4DG68|A0A0C4DG68_HUMAN,tr|H0YEH2|H0YEH2_HUMAN,tr|Q5T1Z4|Q5T1Z4_HUMAN,tr|H0YDC5|H0YDC5_HUMAN,tr|E9PR38|E9PR38_HUMAN" 10 900.4796 1.83 25060 6524 2 900.47928 451.2471 Pumilio homolog 2 OS=Homo sapiens OX=9606 GN=PUM2 PE=1 SV=2 6 1819.9 - 4.57E+06 - - - -0.3909 - 1.338 0.329 - 68.1 1 2 0 -0.0004 8 0 0 0 2.24E+09 1.23E+09 - - - 2.3491 0.9963 221125_WJC_METTL3_EV_vs_WT_F03.06525.06525.2 0.12 12-Jul K.EVAALC[160.03]R[166.11].Y "sp|P12956|XRCC6_HUMAN,tr|B1AHC9|B1AHC9_HUMAN" 2 827.4199 2.06 25061 6525 2 827.420215 414.7172 X-ray repair cross-complementing protein 6 OS=Homo sapiens OX=9606 GN=XRCC6 PE=1 SV=2 6.09 1819.9 - 1.89E+06 - - - 0.3892 - 1.372 0.179 - 282.5 1 2 0 0.0003 7 0 0 0 1.23E+08 5.95E+07 - - - 1.3651 0.9994 221125_WJC_METTL3_EV_vs_WT_F03.06528.06528.2 0.204 14-Aug K.IAASSSFR.S sp|Q99961|SH3G1_HUMAN 1 837.4345 1.48 25062 6528 2 837.433962 419.7245 Endophilin-A2 OS=Homo sapiens OX=9606 GN=SH3GL1 PE=1 SV=1 9.75 1820.4 - 3.20E+06 - - - -0.603 - 1.631 0.312 - 162.9 1 2 0 -0.0005 8 0 0 0 4.20E+08 2.85E+08 - - - 2.8207 0.9714 221125_WJC_METTL3_EV_vs_WT_F03.06529.06529.2 2.38 14-Jul R.GLMEEGEK[136.11].L "sp|P82094|TMF1_HUMAN,tr|F8WF45|F8WF45_HUMAN,tr|A0A2R8Y7M0|A0A2R8Y7M0_HUMAN" 3 899.415 1.35 25063 6529 2 899.414993 450.7148 TATA element modulatory factor OS=Homo sapiens OX=9606 GN=TMF1 PE=1 SV=2 4.25 1820.4 - 6.89E+06 - - - 0.0111 - 0.919 0.154 - 81.2 1 2 0 0 8 0 0 0 9.11E+07 6.75E+07 - - - -0.0763 0.9991 221125_WJC_METTL3_EV_vs_WT_F03.06530.06530.2 0.0255 14-Aug R.AFDSAVAK.A "sp|Q16891|MIC60_HUMAN,tr|B9A067|B9A067_HUMAN,tr|C9J406|C9J406_HUMAN,tr|H7C463|H7C463_HUMAN" 4 807.4127 1.54 25064 6530 2 807.412279 404.7136 MICOS complex subunit MIC60 OS=Homo sapiens OX=9606 GN=IMMT PE=1 SV=1 5.88 1820.5 - 5.64E+06 - - - -0.483 - 1.31 0.352 - 184.3 1 2 0 -0.0004 8 0 0 0 1.22E+09 7.94E+08 - - - 2.4551 0.9944 221125_WJC_METTL3_EV_vs_WT_F03.06531.06531.2 3.35 14-Sep K.IAASSSFR[166.11].S sp|Q99961|SH3G1_HUMAN 1 847.4427 1.48 25065 6531 2 847.443186 424.7286 Endophilin-A2 OS=Homo sapiens OX=9606 GN=SH3GL1 PE=1 SV=1 9.75 1820.5 - 3.26E+06 - - - 0.5298 - 1.561 0.096 - 255.7 1 2 0 0.0004 8 0 0 0 4.20E+08 2.85E+08 - - - 1.093 0.9915 221125_WJC_METTL3_EV_vs_WT_F03.06543.06543.2 0.123 14-Aug R.AFDSAVAK[136.11].A "sp|Q16891|MIC60_HUMAN,tr|B9A067|B9A067_HUMAN,tr|C9J406|C9J406_HUMAN,tr|H7C463|H7C463_HUMAN" 4 815.4269 1.54 25069 6543 2 815.425037 408.7207 MICOS complex subunit MIC60 OS=Homo sapiens OX=9606 GN=IMMT PE=1 SV=1 5.88 1822.2 - 1.08E+07 - - - -2.2467 - 1.117 0.274 - 180.2 1 2 0 -0.0018 8 0 0 0 1.21E+09 7.89E+08 - - - 1.3979 0.9938 221125_WJC_METTL3_EV_vs_WT_F03.06544.06544.2 0.0165 14-Jul K.YYGAQTVR.S "sp|P07954|FUMH_HUMAN,tr|A0A804HKE6|A0A804HKE6_HUMAN,tr|A0A804HI24|A0A804HI24_HUMAN" 3 956.4716 1.93 25070 6544 2 956.468884 479.2431 "Fumarate hydratase, mitochondrial OS=Homo sapiens OX=9606 GN=FH PE=1 SV=3" 8.59 1822.3 - 639680 - - - -2.8187 - 1.094 0.36 - 139.1 1 2 0 -0.0027 8 0 0 0 2.66E+07 1.37E+07 - - - 1.9701 0.9986 221125_WJC_METTL3_EV_vs_WT_F03.06562.06562.2 0.0152 12-Aug R.MAAPIDR.V "sp|P52272|HNRPM_HUMAN,tr|M0R2I7|M0R2I7_HUMAN,tr|A0A087X0X3|A0A087X0X3_HUMAN,tr|M0QZM1|M0QZM1_HUMAN" 4 772.3902 1.6 25075 6562 2 772.389309 387.2024 Heterogeneous nuclear ribonucleoprotein M OS=Homo sapiens OX=9606 GN=HNRNPM PE=1 SV=3 5.59 1824.9 - 8.29E+06 - - - -1.1005 - 1.913 0.159 - 409.1 1 2 0 -0.0008 7 0 0 0 2.58E+09 1.61E+09 - - - 2.2705 0.9832 221125_WJC_METTL3_EV_vs_WT_F03.06570.06570.2 8.65 14-Sep K.AGIIASAR[166.11].A sp|P13639|EF2_HUMAN 1 767.4529 0.05 25079 6570 2 767.45147 384.7337 Elongation factor 2 OS=Homo sapiens OX=9606 GN=EEF2 PE=1 SV=4 9.79 1825.9 - 1.81E+06 - - - -1.8724 - 1.657 0.058 - 213.3 4 2 0 -0.0014 8 0 0 0 4.70E+07 8.87E+08 - - - 0.7231 0.9989 221125_WJC_METTL3_EV_vs_WT_F03.06574.06574.2 0.0091 20-Jun R.ADTQTYQPYNK.D sp|P84090|ERH_HUMAN 1 1327.6044 4.93 25082 6574 2 1327.604852 664.8095 Enhancer of rudimentary homolog OS=Homo sapiens OX=9606 GN=ERH PE=1 SV=1 5.88 1826.3 - 487154 - - - 0.3066 - 1.437 0.316 - 43 1 2 0 0.0004 11 0 0 0 1.15E+07 2.33E+06 - - - 2.3557 0.9927 221125_WJC_METTL3_EV_vs_WT_F03.06587.06587.2 0.309 14-Jul R.AIETLSGK[136.11].V "sp|Q9Y6M1|IF2B2_HUMAN,tr|F8W930|F8W930_HUMAN" 2 825.4687 1.07 25087 6587 2 825.467482 413.7416 Insulin-like growth factor 2 mRNA-binding protein 2 OS=Homo sapiens OX=9606 GN=IGF2BP2 PE=1 SV=2 6.05 1828.1 - 2.87E+06 - - - -1.5155 - 1.366 0.158 - 152.2 1 2 0 -0.0013 8 0 0 0 1.36E+08 1.27E+08 - - - 1.1482 0.9954 221125_WJC_METTL3_EV_vs_WT_F03.06592.06592.2 1.2 12-Jul R.MTEDALR[166.11].L "sp|Q8WXI9|P66B_HUMAN,tr|A0A1B0GVS4|A0A1B0GVS4_HUMAN,tr|A0A0U1RR34|A0A0U1RR34_HUMAN,tr|A0A0U1RRM1|A0A0U1RRM1_HUMAN,tr|A0A0U1RRK3|A0A0U1RRK3_HUMAN" 5 844.3988 1.79 25090 6592 2 844.396672 423.2067 Transcriptional repressor p66-beta OS=Homo sapiens OX=9606 GN=GATAD2B PE=1 SV=1 4.37 1828.6 - 2.95E+06 - - - -2.5474 - 1.469 0.243 - 234.5 1 2 0 -0.0022 7 0 0 0 3.99E+08 2.23E+08 - - - 2.0537 0.9908 221125_WJC_METTL3_EV_vs_WT_F03.06596.06596.2 0.457 12-Jun R.MTEDALR.L "sp|Q8WXI9|P66B_HUMAN,tr|A0A1B0GVS4|A0A1B0GVS4_HUMAN,tr|A0A0U1RR34|A0A0U1RR34_HUMAN,tr|A0A0U1RRM1|A0A0U1RRM1_HUMAN,tr|A0A0U1RRK3|A0A0U1RRK3_HUMAN" 5 834.3906 1.31 25092 6596 2 834.388678 418.2026 Transcriptional repressor p66-beta OS=Homo sapiens OX=9606 GN=GATAD2B PE=1 SV=1 4.37 1829 - 5.82E+06 - - - -2.2471 - 1.449 0.171 - 157.6 2 2 0 -0.0019 7 0 0 0 5.03E+08 3.82E+08 - - - 1.3441 0.9998 221125_WJC_METTL3_EV_vs_WT_F03.06598.06598.2 0.000145 13/18 R.VLEAAAQAAR.D "sp|Q9NPD3|EXOS4_HUMAN,tr|E9PI41|E9PI41_HUMAN" 2 998.5509 0.86 25093 6598 2 998.550428 500.2827 Exosome complex component RRP41 OS=Homo sapiens OX=9606 GN=EXOSC4 PE=1 SV=3 5.97 1829.2 - 1.28E+06 - - - -0.4657 - 2.496 0.369 - 706.2 1 2 0 -0.0005 10 0 0 0 9.03E+07 1.05E+08 - - - 4.3195 0.766 221125_WJC_METTL3_EV_vs_WT_F03.06607.06607.2 0.0324 12-Jun Q.NVPLEDR[166.11].V "sp|Q00839|HNRPU_HUMAN,tr|A0A1W2PQL0|A0A1W2PQL0_HUMAN,tr|A0A1W2PPL4|A0A1W2PPL4_HUMAN,tr|A0A1W2PQ74|A0A1W2PQ74_HUMAN,tr|Q5RI18|Q5RI18_HUMAN,tr|A0A1W2PP35|A0A1W2PP35_HUMAN,tr|A0A1W2PPS1|A0A1W2PPS1_HUMAN,tr|A0A1W2PRZ7|A0A1W2PRZ7_HUMAN,tr|A0A1W2PPH7|A0A1W2PPH7_HUMAN,tr|A0A1W2PQD4|A0A1W2PQD4_HUMAN,tr|A0A1W2PP34|A0A1W2PP34_HUMAN,tr|A0A1X7SBS1|A0A1X7SBS1_HUMAN" 12 851.4377 1.33 25096 6607 2 851.436558 426.7261 Heterogeneous nuclear ribonucleoprotein U OS=Homo sapiens OX=9606 GN=HNRNPU PE=1 SV=6 4.37 1830.5 - 3.44E+06 - - - -1.2837 - 1.137 0.254 - 172.6 1 1 0 -0.0011 7 0 0 0 2.76E+08 2.07E+08 - - - 1.3235 0.9996 221125_WJC_METTL3_EV_vs_WT_F03.06608.06608.2 8.09E-05 16-Sep K.LLDGPSTEK.D "sp|P23193|TCEA1_HUMAN,tr|A0A1W2PRL9|A0A1W2PRL9_HUMAN,tr|A0A1W2PPZ5|A0A1W2PPZ5_HUMAN,tr|E5RIS7|E5RIS7_HUMAN" 4 958.4971 3.48 25097 6608 2 958.49876 480.2558 Transcription elongation factor A protein 1 OS=Homo sapiens OX=9606 GN=TCEA1 PE=1 SV=2 4.37 1830.6 - 583744 - - - 1.7037 - 1.695 0.453 - 195.6 1 2 0 0.0016 9 0 0 0 1.26E+08 3.63E+07 - - - 3.913 0.7823 221125_WJC_METTL3_EV_vs_WT_F03.06609.06609.2 1.11 12-Jun K.IAGYVTH.L "sp|P08708|RS17_HUMAN,tr|H3BNC9|H3BNC9_HUMAN,tr|H0YN88|H0YN88_HUMAN,tr|A0A075B716|A0A075B716_HUMAN" 4 759.3915 - 25098 6609 2 759.390607 380.703 40S ribosomal protein S17 OS=Homo sapiens OX=9606 GN=RPS17 PE=1 SV=2 6.74 1830.7 - 4.25E+06 - - - -1.2273 - 1.368 0.181 - 83.1 1 1 0 -0.0009 7 0 0 0 - - - - - 1.3704 0.9927 221125_WJC_METTL3_EV_vs_WT_F03.06613.06613.2 0.355 12-Jun K.FTGSEIR[166.11].V "sp|O75439|MPPB_HUMAN,sp|P31930|QCR1_HUMAN,tr|G3V0E4|G3V0E4_HUMAN" 3 818.4162 2.99 25100 6613 2 818.415011 410.2154 Mitochondrial-processing peptidase subunit beta OS=Homo sapiens OX=9606 GN=PMPCB PE=1 SV=2 6 1831.2 - 4.81E+06 - - - -1.4381 - 1.162 0.217 - 104.3 1 2 0 -0.0012 7 0 0 0 6.19E+08 2.07E+08 - - - 1.1191 0.8881 221125_WJC_METTL3_EV_vs_WT_F03.06619.06619.2 7.06 12-May R.FSGVPDR.F "sp|A0A075B6R9|KVD24_HUMAN,sp|A0A0C4DH68|KV224_HUMAN,sp|A2NJV5|KV229_HUMAN,sp|A0A075B6S2|KVD29_HUMAN,sp|A0A0A0MRZ7|KVD26_HUMAN" 5 776.3817 4.52 25104 6619 2 776.382622 389.1981 Probable non-functional immunoglobulin kappa variable 2D-24 OS=Homo sapiens OX=9606 GN=IGKV2D-24 PE=1 SV=1 5.84 1831.8 - 1.64E+06 - - - 1.1837 - 0.988 0.081 - 78.6 6 2 0 0.0009 7 0 0 0 3.37E+08 7.47E+07 - - - -0.7469 0.9979 221125_WJC_METTL3_EV_vs_WT_F03.06622.06622.2 0.0567 14-Aug R.AIETLSGK.V "sp|Q9Y6M1|IF2B2_HUMAN,tr|F8W930|F8W930_HUMAN" 2 817.4545 1.09 25105 6622 2 817.453825 409.7345 Insulin-like growth factor 2 mRNA-binding protein 2 OS=Homo sapiens OX=9606 GN=IGF2BP2 PE=1 SV=2 6.05 1832.2 - 3.85E+06 - - - -0.8661 - 1.443 0.23 - 159.3 1 2 0 -0.0007 8 0 0 0 1.35E+08 1.23E+08 - - - 1.8456 0.792 221125_WJC_METTL3_EV_vs_WT_F03.06626.06626.2 0.18 16-Jul V.PSSPAEAEK[136.11].G "sp|Q5TAX3|TUT4_HUMAN,tr|X6R5G7|X6R5G7_HUMAN,tr|E9PKY2|E9PKY2_HUMAN,tr|A0A0C4DFM7|A0A0C4DFM7_HUMAN,tr|E9PRG2|E9PRG2_HUMAN" 5 922.4487 1.36 25107 6626 2 922.447902 462.2316 Terminal uridylyltransferase 4 OS=Homo sapiens OX=9606 GN=TUT4 PE=1 SV=3 4.53 1832.7 - 737608 - - - -0.8933 - 1.275 0.211 - 147.9 1 1 0 -0.0008 9 0 0 0 9.44E+07 6.92E+07 - - - 1.302 0.9757 221125_WJC_METTL3_EV_vs_WT_F03.06630.06630.2 1.59 12-Jul K.TAPFDSR.F "sp|P14854|CX6B1_HUMAN,tr|A0A494C160|A0A494C160_HUMAN,tr|K7EQD3|K7EQD3_HUMAN" 3 792.3766 7.58 25110 6630 2 792.37661 397.1956 Cytochrome c oxidase subunit 6B1 OS=Homo sapiens OX=9606 GN=COX6B1 PE=1 SV=2 5.5 1833.1 - 991679 - - - -0.0088 - 0.952 0.155 - 129.7 1 2 0 0 7 0 0 0 1.76E+08 2.32E+07 - - - 0.03 0.9997 221125_WJC_METTL3_EV_vs_WT_F03.06633.06633.2 0.0805 16-Nov K.LLADQAEAR[166.11].R "sp|P84098|RL19_HUMAN,tr|J3KTE4|J3KTE4_HUMAN,tr|A0A7I2YQG2|A0A7I2YQG2_HUMAN,tr|J3QR09|J3QR09_HUMAN" 4 995.5275 0.99 25111 6633 2 995.527345 498.771 60S ribosomal protein L19 OS=Homo sapiens OX=9606 GN=RPL19 PE=1 SV=1 4.37 1833.6 - 3.97E+06 - - - -0.1848 - 2.112 0.32 - 401.1 1 2 0 -0.0002 9 0 0 0 1.12E+09 1.13E+09 - - - 3.5674 0.9974 221125_WJC_METTL3_EV_vs_WT_F03.06634.06634.2 0.169 14-Aug R.VEATVIEK[136.11].T "sp|Q7Z2W9|RM21_HUMAN,tr|H3BUY0|H3BUY0_HUMAN" 2 895.5106 1.45 25112 6634 2 895.511048 448.7626 "39S ribosomal protein L21, mitochondrial OS=Homo sapiens OX=9606 GN=MRPL21 PE=1 SV=2" 4.53 1833.6 - 931933 - - - 0.5025 - 1.561 0.17 - 187.5 1 2 0 0.0004 8 0 0 0 5.70E+07 3.94E+07 - - - 1.6396 0.8986 221125_WJC_METTL3_EV_vs_WT_F03.06638.06638.2 0.0157 12-Jun Q.NVPLEDR.V "sp|Q00839|HNRPU_HUMAN,tr|A0A1W2PQL0|A0A1W2PQL0_HUMAN,tr|A0A1W2PPL4|A0A1W2PPL4_HUMAN,tr|A0A1W2PQ74|A0A1W2PQ74_HUMAN,tr|Q5RI18|Q5RI18_HUMAN,tr|A0A1W2PP35|A0A1W2PP35_HUMAN,tr|A0A1W2PPS1|A0A1W2PPS1_HUMAN,tr|A0A1W2PRZ7|A0A1W2PRZ7_HUMAN,tr|A0A1W2PPH7|A0A1W2PPH7_HUMAN,tr|A0A1W2PQD4|A0A1W2PQD4_HUMAN,tr|A0A1W2PP34|A0A1W2PP34_HUMAN,tr|A0A1X7SBS1|A0A1X7SBS1_HUMAN" 12 841.4294 1.18 25114 6638 2 841.429215 421.722 Heterogeneous nuclear ribonucleoprotein U OS=Homo sapiens OX=9606 GN=HNRNPU PE=1 SV=6 4.37 1834.1 - 5.38E+06 - - - -0.1973 - 1.256 0.281 - 163.8 1 1 0 -0.0002 7 0 0 0 2.85E+08 2.42E+08 - - - 1.8386 0.999 221125_WJC_METTL3_EV_vs_WT_F03.06642.06642.2 0.0738 12-Jul R.AQVIYTR.N sp|P62851|RS25_HUMAN 1 849.4709 0.72 25116 6642 2 849.470658 425.7427 40S ribosomal protein S25 OS=Homo sapiens OX=9606 GN=RPS25 PE=1 SV=1 8.79 1834.5 - 7.19E+06 - - - -0.2284 - 1.605 0.245 - 330.8 1 2 0 -0.0002 7 0 0 0 2.15E+09 2.97E+09 - - - 2.3496 0.9969 221125_WJC_METTL3_EV_vs_WT_F03.06644.06644.2 0.0727 16-Aug R.MGGEEAEIR[166.11].F sp|Q08211|DHX9_HUMAN 1 1000.4523 1.11 25118 6644 2 1000.453072 501.2334 ATP-dependent RNA helicase A OS=Homo sapiens OX=9606 GN=DHX9 PE=1 SV=4 4.25 1834.7 - 2.45E+06 - - - 0.7567 - 1.093 0.308 - 132.3 1 2 0 0.0008 9 0 0 0 2.03E+08 1.83E+08 - - - 1.5729 0.9835 221125_WJC_METTL3_EV_vs_WT_F03.06647.06647.2 0.0329 12-Jul K.FGVQTDR.Q sp|Q14247|SRC8_HUMAN 1 821.4032 0.73 25119 6647 2 821.404396 411.7089 Src substrate cortactin OS=Homo sapiens OX=9606 GN=CTTN PE=1 SV=2 5.84 1835.1 - 1.19E+06 - - - 1.4974 - 1.382 0.078 - 171.5 1 2 0 0.0012 7 0 0 0 6.38E+07 8.73E+07 - - - 0.6419 0.999 221125_WJC_METTL3_EV_vs_WT_F03.06648.06648.2 0.0256 14-Sep R.VEATVIEK.T "sp|Q7Z2W9|RM21_HUMAN,tr|H3BUY0|H3BUY0_HUMAN" 2 887.4964 1.45 25120 6648 2 887.497453 444.7555 "39S ribosomal protein L21, mitochondrial OS=Homo sapiens OX=9606 GN=MRPL21 PE=1 SV=2" 4.53 1835.2 - 1.29E+06 - - - 1.1887 - 1.663 0.287 - 257.3 1 2 0 0.0011 8 0 0 0 5.72E+07 3.94E+07 - - - 2.6944 0.9941 221125_WJC_METTL3_EV_vs_WT_F03.06649.06649.2 0.0148 18-Sep R.VLEAAAQAAR[166.11].D "sp|Q9NPD3|EXOS4_HUMAN,tr|E9PI41|E9PI41_HUMAN" 2 1008.5592 0.95 25121 6649 2 1008.554775 505.2869 Exosome complex component RRP41 OS=Homo sapiens OX=9606 GN=EXOSC4 PE=1 SV=3 5.97 1835.3 - 2.07E+06 - - - -4.3508 - 1.79 0.322 - 295.5 1 2 0 -0.0044 10 0 0 0 1.04E+08 1.09E+08 - - - 3.0431 0.999 221125_WJC_METTL3_EV_vs_WT_F03.06657.06657.2 0.00313 16-Sep R.MGGEEAEIR.F sp|Q08211|DHX9_HUMAN 1 990.444 0.98 25124 6657 2 990.441768 496.2293 ATP-dependent RNA helicase A OS=Homo sapiens OX=9606 GN=DHX9 PE=1 SV=4 4.25 1836.4 - 2.47E+06 - - - -2.299 - 1.758 0.359 - 176.1 1 2 0 -0.0023 9 0 0 0 2.08E+08 2.12E+08 - - - 3.3241 0.9983 221125_WJC_METTL3_EV_vs_WT_F03.06659.06659.2 0.0277 14-Aug R.VEATVIEK[136.11].T "sp|Q7Z2W9|RM21_HUMAN,tr|H3BUY0|H3BUY0_HUMAN" 2 895.5106 1.45 25125 6659 2 895.510912 448.7626 "39S ribosomal protein L21, mitochondrial OS=Homo sapiens OX=9606 GN=MRPL21 PE=1 SV=2" 4.53 1836.6 - 1.11E+06 - - - 0.3506 - 1.716 0.177 - 175.9 1 2 0 0.0003 8 0 0 0 5.70E+07 3.94E+07 - - - 1.9768 0.9718 221125_WJC_METTL3_EV_vs_WT_F03.06665.06665.2 0.706 12-Jun K.DTETVLK[136.11].T sp|Q9NP61|ARFG3_HUMAN 1 812.4371 1.49 25128 6665 2 812.437501 407.2258 ADP-ribosylation factor GTPase-activating protein 3 OS=Homo sapiens OX=9606 GN=ARFGAP3 PE=1 SV=1 4.37 1837.3 - 1.04E+06 - - - 0.4948 - 1.342 0.031 - 134.2 3 2 0 0.0004 7 0 0 0 1.04E+08 6.98E+07 - - - -0.0112 0.9998 221125_WJC_METTL3_EV_vs_WT_F03.06672.06672.2 0.000659 18-Oct R.LSVAAQEAAR.L sp|Q15149|PLEC_HUMAN 1 1014.5458 1.27 25132 6672 2 1014.544873 508.2802 Plectin OS=Homo sapiens OX=9606 GN=PLEC PE=1 SV=3 6 1838.1 - 299617 - - - -0.9216 - 1.933 0.43 - 354.2 1 2 0 -0.0009 10 0 0 0 3.55E+07 2.79E+07 - - - 4.0564 0.991 221125_WJC_METTL3_EV_vs_WT_F03.06676.06676.2 0.202 12-Jun R.EELMESR.M "sp|P20700|LMNB1_HUMAN,tr|E9PBF6|E9PBF6_HUMAN,tr|A0A0D9SFE5|A0A0D9SFE5_HUMAN" 3 892.396 0.57 25135 6676 2 892.395631 447.2053 Lamin-B1 OS=Homo sapiens OX=9606 GN=LMNB1 PE=1 SV=2 4.25 1838.5 - 814097 - - - -0.4494 - 1.259 0.126 - 169.4 1 2 0 -0.0004 7 0 0 0 1.45E+08 2.54E+08 - - - 0.7013 0.953 221125_WJC_METTL3_EV_vs_WT_F03.06677.06677.2 0.00201 14-Jul Y.YVSNEELR[166.11].G sp|P26641|EF1G_HUMAN 1 1018.4959 0.92 25136 6677 2 1018.495095 510.2552 Elongation factor 1-gamma OS=Homo sapiens OX=9606 GN=EEF1G PE=1 SV=3 4.53 1838.6 - 388712 - - - -0.7845 - 1.481 0.327 - 136.7 1 1 0 -0.0008 8 0 0 0 2.85E+07 3.11E+07 - - - 2.6404 0.9951 221125_WJC_METTL3_EV_vs_WT_F03.06680.06680.2 0.0661 12-Jul K.YIENMSR[166.11].G "sp|Q8IWS0|PHF6_HUMAN,tr|Q5JRC6|Q5JRC6_HUMAN,tr|A0A0D9SGE8|A0A0D9SGE8_HUMAN" 3 921.4254 0.78 25137 6680 2 921.42372 461.72 PHD finger protein 6 OS=Homo sapiens OX=9606 GN=PHF6 PE=1 SV=1 6 1839 - 2.68E+06 - - - -1.7929 - 1.193 0.268 - 158.9 1 2 0 -0.0017 7 0 0 0 1.59E+08 2.04E+08 - - - 1.5791 0.9985 221125_WJC_METTL3_EV_vs_WT_F03.06681.06681.2 0.00919 14-Sep R.QVFGEATK.Q "sp|P07339|CATD_HUMAN,tr|A0A1B0GW44|A0A1B0GW44_HUMAN,tr|A0A1B0GVD5|A0A1B0GVD5_HUMAN,tr|A0A1B0GV23|A0A1B0GV23_HUMAN,tr|C9JH19|C9JH19_HUMAN,tr|A0A1B0GWE8|A0A1B0GWE8_HUMAN,tr|A0A1B0GU03|A0A1B0GU03_HUMAN,tr|A0A1B0GVP3|A0A1B0GVP3_HUMAN,tr|F8WD96|F8WD96_HUMAN,tr|A0A1B0GU92|A0A1B0GU92_HUMAN,tr|F8W787|F8W787_HUMAN" 11 878.4498 4.85 25138 6681 2 878.450223 440.2322 Cathepsin D OS=Homo sapiens OX=9606 GN=CTSD PE=1 SV=1 6 1839.1 - 1.05E+06 - - - 0.502 - 1.488 0.255 - 267.4 1 2 0 0.0004 8 0 0 0 1.85E+08 3.82E+07 - - - 2.1229 0.9996 221125_WJC_METTL3_EV_vs_WT_F03.06685.06685.2 0.0248 18-Sep R.LSVAAQEAAR[166.11].L sp|Q15149|PLEC_HUMAN 1 1024.5541 1.26 25140 6685 2 1024.554458 513.2843 Plectin OS=Homo sapiens OX=9606 GN=PLEC PE=1 SV=3 6 1839.7 - 313658 - - - 0.3709 - 2.051 0.303 - 231 1 2 0 0.0004 10 0 0 0 3.57E+07 2.83E+07 - - - 3.2839 0.9763 221125_WJC_METTL3_EV_vs_WT_F03.06696.06696.2 0.12 12-Jun K.YIENMSR.G "sp|Q8IWS0|PHF6_HUMAN,tr|Q5JRC6|Q5JRC6_HUMAN,tr|A0A0D9SGE8|A0A0D9SGE8_HUMAN" 3 911.4171 0.77 25143 6696 2 911.414995 456.7158 PHD finger protein 6 OS=Homo sapiens OX=9606 GN=PHF6 PE=1 SV=1 6 1841.3 - 3.00E+06 - - - -2.3118 - 1.162 0.16 - 124.3 1 2 0 -0.0021 7 0 0 0 1.56E+08 2.03E+08 - - - 0.6978 0.996 221125_WJC_METTL3_EV_vs_WT_F03.06699.06699.2 0.00281 20-Oct K.LLQAAAGASAR[166.11].A "sp|Q96T76|MMS19_HUMAN,tr|H7C1W5|H7C1W5_HUMAN" 2 1037.5857 0.58 25144 6699 2 1037.58861 519.8001 MMS19 nucleotide excision repair protein homolog OS=Homo sapiens OX=9606 GN=MMS19 PE=1 SV=2 9.75 1841.7 - 404561 - - - 2.7921 - 1.515 0.297 - 241.5 1 2 0 0.0029 11 0 0 0 5.65E+06 9.79E+06 - - - 2.3575 0.9978 221125_WJC_METTL3_EV_vs_WT_F03.06714.06714.2 0.0176 16-Jun R.TQAPAVATT.- "sp|P15880|RS2_HUMAN,tr|E9PQD7|E9PQD7_HUMAN,tr|H0YEN5|H0YEN5_HUMAN" 3 858.4447 - 25149 6714 2 858.443769 430.2296 40S ribosomal protein S2 OS=Homo sapiens OX=9606 GN=RPS2 PE=1 SV=2 5.19 1843.6 - 2.49E+07 - - - -1.081 - 1.173 0.321 - 137 1 2 0 -0.0009 9 0 0 0 - - - - - 1.8732 0.9967 221125_WJC_METTL3_EV_vs_WT_F03.06719.06719.2 0.0864 12-Jul K.MAQFDAK.K sp|P26641|EF1G_HUMAN 1 809.3742 0.95 25152 6719 2 809.372832 405.6944 Elongation factor 1-gamma OS=Homo sapiens OX=9606 GN=EEF1G PE=1 SV=3 5.59 1844.1 - 2.31E+06 - - - -1.6593 - 1.147 0.319 - 181.7 1 2 0 -0.0013 7 0 0 0 2.27E+08 2.41E+08 - - - 1.8313 0.9932 221125_WJC_METTL3_EV_vs_WT_F03.06720.06720.2 0.541 12-Jul R.TPSQIIR[166.11].K "sp|Q01804|OTUD4_HUMAN,tr|D6RI06|D6RI06_HUMAN" 2 823.4791 1.84 25153 6720 2 823.4789 412.7468 OTU domain-containing protein 4 OS=Homo sapiens OX=9606 GN=OTUD4 PE=1 SV=4 9.41 1844.2 - 2.00E+06 - - - -0.2696 - 1.301 0.137 - 199.8 1 2 0 -0.0002 7 0 0 0 1.52E+08 8.27E+07 - - - 0.8866 0.9979 221125_WJC_METTL3_EV_vs_WT_F03.06721.06721.2 0.365 16-Sep K.VGTLVGEDK.Y "sp|Q9UI09|NDUAC_HUMAN,tr|H0YID5|H0YID5_HUMAN,tr|F8VRD8|F8VRD8_HUMAN,tr|H0YIT1|H0YIT1_HUMAN,tr|A0A804HJF8|A0A804HJF8_HUMAN,tr|A0A804HK60|A0A804HK60_HUMAN,tr|A0A804HHX9|A0A804HHX9_HUMAN" 7 916.4866 1.22 25154 6721 2 916.484308 459.2506 NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 12 OS=Homo sapiens OX=9606 GN=NDUFA12 PE=1 SV=1 4.37 1844.2 - 2.06E+06 - - - -2.4594 - 1.957 0.231 - 236.2 1 2 0 -0.0023 9 0 0 0 1.01E+08 8.24E+07 - - - 2.6889 0.9986 221125_WJC_METTL3_EV_vs_WT_F03.06724.06724.2 0.162 12-Jun K.MAQFDAK[136.11].K sp|P26641|EF1G_HUMAN 1 817.3884 0.95 25155 6724 2 817.38745 409.7015 Elongation factor 1-gamma OS=Homo sapiens OX=9606 GN=EEF1G PE=1 SV=3 5.59 1844.6 - 4.27E+06 - - - -1.1317 - 1.262 0.337 - 136 1 2 0 -0.0009 7 0 0 0 2.27E+08 2.39E+08 - - - 2.2671 0.9968 221125_WJC_METTL3_EV_vs_WT_F03.06725.06725.2 0.0706 14-Jul K.AIQALNGR.W "sp|Q9UHX1|PUF60_HUMAN,tr|A0A0J9YYL3|A0A0J9YYL3_HUMAN,tr|A0A0J9YXX5|A0A0J9YXX5_HUMAN,tr|A0A0J9YXJ8|A0A0J9YXJ8_HUMAN,tr|A0A0J9YVP6|A0A0J9YVP6_HUMAN" 5 841.477 0.42 25156 6725 2 841.476144 421.7458 Poly(U)-binding-splicing factor PUF60 OS=Homo sapiens OX=9606 GN=PUF60 PE=1 SV=1 9.79 1844.7 - 2.90E+06 - - - -1.0173 - 1.373 0.214 - 175.4 1 2 0 -0.0009 8 0 0 0 1.38E+08 3.28E+08 - - - 1.5774 0.9995 221125_WJC_METTL3_EV_vs_WT_F03.06731.06731.2 0.0104 18-Sep K.LIANNTTVER.R sp|O96019|ACL6A_HUMAN 1 1129.6091 0.95 25160 6731 2 1129.610918 565.8118 Actin-like protein 6A OS=Homo sapiens OX=9606 GN=ACTL6A PE=1 SV=1 6 1845.3 - 375491 - - - 1.5767 - 1.874 0.398 - 262.7 1 2 0 0.0018 10 0 0 0 4.08E+07 4.30E+07 - - - 3.7332 0.9958 221125_WJC_METTL3_EV_vs_WT_F03.06732.06732.2 0.112 18-Jul K.LIANNTTVER[166.11].R sp|O96019|ACL6A_HUMAN 1 1139.6174 0.95 25161 6732 2 1139.615282 570.816 Actin-like protein 6A OS=Homo sapiens OX=9606 GN=ACTL6A PE=1 SV=1 6 1845.5 - 315681 - - - -1.8647 - 1.371 0.245 - 130 1 2 0 -0.0021 10 0 0 0 4.08E+07 4.30E+07 - - - 1.7307 0.9993 221125_WJC_METTL3_EV_vs_WT_F03.06740.06740.2 0.000536 18-Aug R.IVEQDTMPPK.G "sp|O00571|DDX3X_HUMAN,sp|O15523|DDX3Y_HUMAN,tr|A0A2R8YFR4|A0A2R8YFR4_HUMAN,tr|A0A2R8YCW1|A0A2R8YCW1_HUMAN,tr|A0A2R8YDH3|A0A2R8YDH3_HUMAN,tr|A0A2R8YDT5|A0A2R8YDT5_HUMAN,tr|A0A2R8Y645|A0A2R8Y645_HUMAN,tr|A0A2R8YF78|A0A2R8YF78_HUMAN,tr|A0A0D9SFB3|A0A0D9SFB3_HUMAN,tr|A0A2R8YFS5|A0A2R8YFS5_HUMAN,tr|A0A0D9SF53|A0A0D9SF53_HUMAN,tr|A0A2R8Y5G6|A0A2R8Y5G6_HUMAN,tr|A0A2R8Y7T2|A0A2R8Y7T2_HUMAN,tr|A0A0D9SG12|A0A0D9SG12_HUMAN,tr|F6S8Q4|F6S8Q4_HUMAN,tr|A0A2U3TZJ9|A0A2U3TZJ9_HUMAN,tr|A0A2R8Y4A4|A0A2R8Y4A4_HUMAN" 17 1156.5798 2.23 25164 6740 2 1156.582284 579.2972 ATP-dependent RNA helicase DDX3X OS=Homo sapiens OX=9606 GN=DDX3X PE=1 SV=3 4.37 1846.6 - 193801 - - - 2.1391 - 1.596 0.455 - 165.4 1 2 0 0.0025 10 0 0 0 1.18E+07 5.29E+06 - - - 3.7058 0.9962 221125_WJC_METTL3_EV_vs_WT_F03.06743.06743.2 0.185 14-Jun K.MVSADAYK[136.11].L "sp|P09543|CN37_HUMAN,tr|C9K0L8|C9K0L8_HUMAN,tr|K7ERZ0|K7ERZ0_HUMAN,tr|K7ERC4|K7ERC4_HUMAN,tr|K7EN66|K7EN66_HUMAN" 5 891.4252 0.47 25165 6743 2 891.424171 446.7199 "2',3'-cyclic-nucleotide 3'-phosphodiesterase OS=Homo sapiens OX=9606 GN=CNP PE=1 SV=2" 5.59 1846.9 - 2.25E+06 - - - -1.1027 - 1.178 0.261 - 99 1 2 0 -0.001 8 0 0 0 4.05E+07 8.56E+07 - - - 1.4625 0.9997 221125_WJC_METTL3_EV_vs_WT_F03.06744.06744.2 0.00589 16-Oct K.VGTLVGEDK[136.11].Y "sp|Q9UI09|NDUAC_HUMAN,tr|H0YID5|H0YID5_HUMAN,tr|F8VRD8|F8VRD8_HUMAN,tr|H0YIT1|H0YIT1_HUMAN,tr|A0A804HJF8|A0A804HJF8_HUMAN,tr|A0A804HK60|A0A804HK60_HUMAN,tr|A0A804HHX9|A0A804HHX9_HUMAN" 7 924.5008 1.29 25166 6744 2 924.499381 463.2577 NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 12 OS=Homo sapiens OX=9606 GN=NDUFA12 PE=1 SV=1 4.37 1847 - 2.44E+06 - - - -1.4938 - 2.052 0.391 - 296.9 1 2 0 -0.0014 9 0 0 0 1.09E+08 8.45E+07 - - - 4.0081 0.9997 221125_WJC_METTL3_EV_vs_WT_F03.06745.06745.2 0.00478 14-Jul K.MVSADAYK.L "sp|P09543|CN37_HUMAN,tr|C9K0L8|C9K0L8_HUMAN,tr|K7ERZ0|K7ERZ0_HUMAN,tr|K7ERC4|K7ERC4_HUMAN,tr|K7EN66|K7EN66_HUMAN" 5 883.411 0.49 25167 6745 2 883.410691 442.7128 "2',3'-cyclic-nucleotide 3'-phosphodiesterase OS=Homo sapiens OX=9606 GN=CNP PE=1 SV=2" 5.59 1847.1 - 1.24E+06 - - - -0.2977 - 1.437 0.47 - 156.9 1 2 0 -0.0003 8 0 0 0 4.06E+07 8.27E+07 - - - 3.6058 0.9903 221125_WJC_METTL3_EV_vs_WT_F03.06746.06746.2 0.759 12-Jul R.VNYIGTK.N "sp|Q15738|NSDHL_HUMAN,tr|C9JDR0|C9JDR0_HUMAN" 2 793.4334 0.89 25168 6746 2 793.432401 397.724 "Sterol-4-alpha-carboxylate 3-dehydrogenase, decarboxylating OS=Homo sapiens OX=9606 GN=NSDHL PE=1 SV=2" 8.56 1847.2 - 998565 - - - -1.2641 - 1.318 0.126 - 160.6 1 2 0 -0.001 7 0 0 0 6.05E+07 6.83E+07 - - - 0.8462 0.9946 221125_WJC_METTL3_EV_vs_WT_F03.06748.06748.2 0.00832 18-Jun R.IVEQDTMPPK[136.11].G "sp|O00571|DDX3X_HUMAN,sp|O15523|DDX3Y_HUMAN,tr|A0A2R8YFR4|A0A2R8YFR4_HUMAN,tr|A0A2R8YCW1|A0A2R8YCW1_HUMAN,tr|A0A2R8YDH3|A0A2R8YDH3_HUMAN,tr|A0A2R8YDT5|A0A2R8YDT5_HUMAN,tr|A0A2R8Y645|A0A2R8Y645_HUMAN,tr|A0A2R8YF78|A0A2R8YF78_HUMAN,tr|A0A0D9SFB3|A0A0D9SFB3_HUMAN,tr|A0A2R8YFS5|A0A2R8YFS5_HUMAN,tr|A0A0D9SF53|A0A0D9SF53_HUMAN,tr|A0A2R8Y5G6|A0A2R8Y5G6_HUMAN,tr|A0A2R8Y7T2|A0A2R8Y7T2_HUMAN,tr|A0A0D9SG12|A0A0D9SG12_HUMAN,tr|F6S8Q4|F6S8Q4_HUMAN,tr|A0A2U3TZJ9|A0A2U3TZJ9_HUMAN,tr|A0A2R8Y4A4|A0A2R8Y4A4_HUMAN" 17 1164.594 1.42 25170 6748 2 1164.590968 583.3043 ATP-dependent RNA helicase DDX3X OS=Homo sapiens OX=9606 GN=DDX3X PE=1 SV=3 4.37 1847.4 - 0 - - - -2.6121 - 1.17 0.337 - 106.4 1 2 0 -0.003 10 0 0 0 7.36E+06 5.18E+06 - - - 1.9674 0.9991 221125_WJC_METTL3_EV_vs_WT_F03.06752.06752.2 0.0901 16-Aug K.VVSSSIVDK[136.11].Y "sp|P62333|PRS10_HUMAN,tr|A0A087X2I1|A0A087X2I1_HUMAN,tr|H0YJC0|H0YJC0_HUMAN,tr|H0YJS8|H0YJS8_HUMAN" 4 940.5321 0.63 25172 6752 2 940.532618 471.2733 26S proteasome regulatory subunit 10B OS=Homo sapiens OX=9606 GN=PSMC6 PE=1 SV=1 5.81 1847.8 - 1.76E+06 - - - 0.5912 - 1.468 0.325 - 167.2 1 2 0 0.0006 9 0 0 0 5.53E+07 8.72E+07 - - - 2.5519 0.9984 221125_WJC_METTL3_EV_vs_WT_F03.06764.06764.2 0.0379 20-Jul R.IVAVTGAEAQK.A "sp|P49588|SYAC_HUMAN,tr|A0A6Q8PGR9|A0A6Q8PGR9_HUMAN,tr|A0A6Q8PFY2|A0A6Q8PFY2_HUMAN,tr|A0A6Q8PFK3|A0A6Q8PFK3_HUMAN,tr|H3BPK7|H3BPK7_HUMAN,tr|A0A6Q8PGB5|A0A6Q8PGB5_HUMAN,tr|A0A6Q8PGE8|A0A6Q8PGE8_HUMAN,tr|A0A6Q8PF33|A0A6Q8PF33_HUMAN,tr|A0A6Q8PGN5|A0A6Q8PGN5_HUMAN" 9 1085.6081 1.21 25179 6764 2 1085.607293 543.8113 "Alanine--tRNA ligase, cytoplasmic OS=Homo sapiens OX=9606 GN=AARS1 PE=1 SV=2" 6 1849.2 - 162233 - - - -0.7194 - 1.554 0.242 - 73.5 1 2 0 -0.0008 11 0 0 0 1.02E+07 8.38E+06 - - - 2.0207 0.9962 221125_WJC_METTL3_EV_vs_WT_F03.06768.06768.2 0.336 14-Jul R.VFQDVAQK[136.11].L "sp|Q9UPQ3|AGAP1_HUMAN,sp|Q96P47|AGAP3_HUMAN,tr|A0A087X044|A0A087X044_HUMAN,tr|H7C5G0|H7C5G0_HUMAN,tr|E7EUN2|E7EUN2_HUMAN,tr|E7ESL9|E7ESL9_HUMAN,tr|H7C4U6|H7C4U6_HUMAN,tr|F5GXM9|F5GXM9_HUMAN,tr|A0A087X1U1|A0A087X1U1_HUMAN,tr|C9J975|C9J975_HUMAN" 10 941.5062 0.72 25180 6768 2 941.504795 471.7604 "Arf-GAP with GTPase, ANK repeat and PH domain-containing protein 1 OS=Homo sapiens OX=9606 GN=AGAP1 PE=1 SV=4" 5.81 1849.8 - 623154 - - - -1.4732 - 1.435 0.22 - 116.9 2 2 0 -0.0014 8 0 0 0 9.14E+06 1.27E+07 - - - 1.6203 0.9976 221125_WJC_METTL3_EV_vs_WT_F03.06777.06777.2 0.118 12-Jun K.VEVDMEK.L "sp|Q969G3|SMCE1_HUMAN,sp|P46459|NSF_HUMAN,tr|A0A2R8Y855|A0A2R8Y855_HUMAN,tr|A0A2R8YES3|A0A2R8YES3_HUMAN,tr|A0A2U3TZQ7|A0A2U3TZQ7_HUMAN,tr|A0A2R8Y7U4|A0A2R8Y7U4_HUMAN,tr|B4DGM3|B4DGM3_HUMAN,tr|J3QKS7|J3QKS7_HUMAN,tr|A0A2R8Y4T4|A0A2R8Y4T4_HUMAN,tr|A0A2R8Y7I9|A0A2R8Y7I9_HUMAN,tr|A0A2R8Y765|A0A2R8Y765_HUMAN,tr|I3L0N3|I3L0N3_HUMAN" 12 848.395 0.64 25185 6777 2 848.3949 425.2048 SWI\SNF-related matrix-associated actin-dependent regulator of chromatin subfamily E member 1 OS=Homo sapiens OX=9606 GN=SMARCE1 PE=1 SV=2 4.14 1850.9 - 2.88E+06 - - - -0.0825 - 1.276 0.247 - 125.9 1 2 0 -0.0001 7 0 0 0 8.41E+07 1.32E+08 - - - 1.6376 0.9983 221125_WJC_METTL3_EV_vs_WT_F03.06778.06778.2 0.0264 12-Jul K.VEVDMEK[136.11].L "sp|Q969G3|SMCE1_HUMAN,sp|P46459|NSF_HUMAN,tr|A0A2R8Y855|A0A2R8Y855_HUMAN,tr|A0A2R8YES3|A0A2R8YES3_HUMAN,tr|A0A2U3TZQ7|A0A2U3TZQ7_HUMAN,tr|A0A2R8Y7U4|A0A2R8Y7U4_HUMAN,tr|B4DGM3|B4DGM3_HUMAN,tr|J3QKS7|J3QKS7_HUMAN,tr|A0A2R8Y4T4|A0A2R8Y4T4_HUMAN,tr|A0A2R8Y7I9|A0A2R8Y7I9_HUMAN,tr|A0A2R8Y765|A0A2R8Y765_HUMAN,tr|I3L0N3|I3L0N3_HUMAN" 12 856.4092 1.26 25186 6778 2 856.410687 429.2119 SWI\SNF-related matrix-associated actin-dependent regulator of chromatin subfamily E member 1 OS=Homo sapiens OX=9606 GN=SMARCE1 PE=1 SV=2 4.14 1851 - 2.11E+06 - - - 1.7713 - 1.525 0.292 - 162.2 1 2 0 0.0015 7 0 0 0 7.85E+07 6.23E+07 - - - 2.5343 0.9989 221125_WJC_METTL3_EV_vs_WT_F03.06782.06782.2 0.139 12-Jul K.IYQDAYR[166.11].A "sp|Q00059|TFAM_HUMAN,tr|H7BYN3|H7BYN3_HUMAN" 2 937.4533 1.12 25188 6782 2 937.452565 469.7339 "Transcription factor A, mitochondrial OS=Homo sapiens OX=9606 GN=TFAM PE=1 SV=1" 5.83 1851.5 - 871697 - - - -0.7851 - 1.525 0.267 - 197.7 1 2 0 -0.0007 7 0 0 0 2.40E+08 2.15E+08 - - - 2.3499 0.9996 221125_WJC_METTL3_EV_vs_WT_F03.06788.06788.2 0.0422 14-Aug K.ISVVSATK[136.11].G "sp|Q9UKV3|ACINU_HUMAN,tr|S4R3H4|S4R3H4_HUMAN,tr|E7EQT4|E7EQT4_HUMAN,tr|G3V3T3|G3V3T3_HUMAN" 4 811.4895 1.68 25192 6788 2 811.490227 406.752 Apoptotic chromatin condensation inducer in the nucleus OS=Homo sapiens OX=9606 GN=ACIN1 PE=1 SV=2 8.75 1852.3 - 2.84E+06 - - - 0.9341 - 1.843 0.357 - 150.6 1 2 0 0.0008 8 0 0 0 1.45E+08 8.64E+07 - - - 3.5215 0.9928 221125_WJC_METTL3_EV_vs_WT_F03.06789.06789.2 0.0597 16-Jul K.LENTSPMVK.S "sp|O75376|NCOR1_HUMAN,tr|E7EVK1|E7EVK1_HUMAN,tr|J3KS29|J3KS29_HUMAN,tr|J3QKP0|J3QKP0_HUMAN,tr|A0A088AWL3|A0A088AWL3_HUMAN" 5 1017.5165 1.55 25193 6789 2 1017.518039 509.7655 Nuclear receptor corepressor 1 OS=Homo sapiens OX=9606 GN=NCOR1 PE=1 SV=2 6 1852.4 - 196567 - - - 1.5302 - 1.372 0.174 - 105.7 1 2 0 0.0016 9 0 0 0 3.34E+06 2.16E+06 - - - 1.2407 0.9975 221125_WJC_METTL3_EV_vs_WT_F03.06794.06794.2 0.215 12-Jul K.IYQDAYR.A "sp|Q00059|TFAM_HUMAN,tr|H7BYN3|H7BYN3_HUMAN" 2 927.445 1.12 25196 6794 2 927.446449 464.7298 "Transcription factor A, mitochondrial OS=Homo sapiens OX=9606 GN=TFAM PE=1 SV=1" 5.83 1852.9 - 2.08E+06 - - - 1.5289 - 1.504 0.236 - 203 1 2 0 0.0014 7 0 0 0 2.40E+08 2.15E+08 - - - 2.0768 0.9986 221125_WJC_METTL3_EV_vs_WT_F03.06795.06795.2 0.0476 12-Aug R.TITVVQR[166.11].Q sp|Q9NW64|RBM22_HUMAN 1 825.4948 0.65 25197 6795 2 825.495552 413.7547 Pre-mRNA-splicing factor RBM22 OS=Homo sapiens OX=9606 GN=RBM22 PE=1 SV=1 9.41 1852.9 - 3.60E+06 - - - 0.9449 - 1.542 0.254 - 217.6 1 2 0 0.0008 7 0 0 0 1.43E+08 2.18E+08 - - - 2.289 0.9474 221125_WJC_METTL3_EV_vs_WT_F03.06797.06797.2 1.68 16-May K.ELGGPDYGK[136.11].V "sp|Q9ULR0|ISY1_HUMAN,tr|A8MVI5|A8MVI5_HUMAN,tr|H0YA89|H0YA89_HUMAN" 3 942.4538 2.08 25199 6797 2 942.455071 472.2342 Pre-mRNA-splicing factor ISY1 homolog OS=Homo sapiens OX=9606 GN=ISY1 PE=1 SV=3 4.37 1853.1 - 822892 - - - 1.3359 - 1.051 0.127 - 63.6 5 2 0 0.0013 9 0 0 0 3.02E+07 1.45E+07 - - - -0.1897 0.998 221125_WJC_METTL3_EV_vs_WT_F03.06802.06802.2 0.632 18-Sep R.ATEGMVVADK[136.11].N "sp|Q99436|PSB7_HUMAN,tr|Q5TBG5|Q5TBG5_HUMAN" 2 1027.5099 0.87 25202 6802 2 1027.511703 514.7622 Proteasome subunit beta type-7 OS=Homo sapiens OX=9606 GN=PSMB7 PE=1 SV=1 4.37 1853.7 - 589422 - - - 1.71 - 1.717 0.245 - 243 1 2 0 0.0018 10 0 0 0 1.35E+07 1.54E+07 - - - 2.3589 0.9996 221125_WJC_METTL3_EV_vs_WT_F03.06803.06803.2 0.00894 20-Oct R.IVAVTGAEAQK[136.11].A "sp|P49588|SYAC_HUMAN,tr|A0A6Q8PGR9|A0A6Q8PGR9_HUMAN,tr|A0A6Q8PFY2|A0A6Q8PFY2_HUMAN,tr|A0A6Q8PFK3|A0A6Q8PFK3_HUMAN,tr|H3BPK7|H3BPK7_HUMAN,tr|A0A6Q8PGB5|A0A6Q8PGB5_HUMAN,tr|A0A6Q8PGE8|A0A6Q8PGE8_HUMAN,tr|A0A6Q8PF33|A0A6Q8PF33_HUMAN,tr|A0A6Q8PGN5|A0A6Q8PGN5_HUMAN" 9 1093.6223 1.21 25203 6803 2 1093.62317 547.8184 "Alanine--tRNA ligase, cytoplasmic OS=Homo sapiens OX=9606 GN=AARS1 PE=1 SV=2" 6 1853.8 - 413548 - - - 0.8193 - 1.95 0.367 - 243.1 1 2 0 0.0009 11 0 0 0 1.02E+07 8.38E+06 - - - 3.558 0.9826 221125_WJC_METTL3_EV_vs_WT_F03.06807.06807.2 0.49 14-Jul K.LSDIPEGK.N "sp|P0C7P4|UCRIL_HUMAN,sp|P47985|UCRI_HUMAN" 2 857.4494 2.03 25205 6807 2 857.450324 429.732 Putative cytochrome b-c1 complex subunit Rieske-like protein 1 OS=Homo sapiens OX=9606 GN=UQCRFS1P1 PE=5 SV=1 4.37 1854.3 - 2.14E+06 - - - 1.0216 - 1.495 0.025 - 134.3 1 2 0 0.0009 8 0 0 0 1.65E+08 8.13E+07 - - - 0.4382 0.7967 221125_WJC_METTL3_EV_vs_WT_F03.06814.06814.2 1.48 14-Aug R.SPGPPALK[136.11].H sp|Q8IU81|I2BP1_HUMAN 1 773.4527 2.98 25210 6814 2 773.45681 387.7336 Interferon regulatory factor 2-binding protein 1 OS=Homo sapiens OX=9606 GN=IRF2BP1 PE=1 SV=1 8.47 1855 - 2.91E+06 - - - 5.3281 - 1.283 0.111 - 147.2 1 2 0 0.0041 8 0 0 0 5.50E+08 1.85E+08 - - - 0.6111 0.9997 221125_WJC_METTL3_EV_vs_WT_F03.06816.06816.2 0.0014 14-Aug K.FAANSDLK.V "sp|Q9BRR6|ADPGK_HUMAN,tr|H3BRS6|H3BRS6_HUMAN,tr|H3BU35|H3BU35_HUMAN" 3 864.4341 0.94 25211 6816 2 864.434326 433.2243 ADP-dependent glucokinase OS=Homo sapiens OX=9606 GN=ADPGK PE=1 SV=1 5.84 1855.2 - 3.85E+06 - - - 0.2244 - 1.547 0.446 - 161.3 1 2 0 0.0002 8 0 0 0 1.22E+08 1.29E+08 - - - 3.651 0.9996 221125_WJC_METTL3_EV_vs_WT_F03.06819.06819.2 0.0209 12-Jul K.FDSEYER.M "sp|P43243|MATR3_HUMAN,tr|A8MXP9|A8MXP9_HUMAN,tr|D6R991|D6R991_HUMAN,tr|A0A0R4J2E8|A0A0R4J2E8_HUMAN,tr|H0Y8T4|H0Y8T4_HUMAN,tr|D6REM6|D6REM6_HUMAN" 6 944.3876 1.32 25212 6819 2 944.388264 473.2011 Matrin-3 OS=Homo sapiens OX=9606 GN=MATR3 PE=1 SV=2 4.14 1855.7 - 2.91E+06 - - - 0.7285 - 1.626 0.373 - 154.6 1 2 0 0.0007 7 0 0 0 5.24E+09 3.96E+09 - - - 3.3361 0.9783 221125_WJC_METTL3_EV_vs_WT_F03.06830.06830.2 0.421 14-Jul K.VISELNGK.N "sp|P05387|RLA2_HUMAN,tr|H0YDD8|H0YDD8_HUMAN" 2 858.4811 1.18 25218 6830 2 858.479765 430.2478 60S acidic ribosomal protein P2 OS=Homo sapiens OX=9606 GN=RPLP2 PE=1 SV=1 5.97 1857 - 3.53E+06 - - - -1.5353 - 1.168 0.121 - 111.8 1 2 0 -0.0013 8 0 0 0 1.07E+10 9.05E+09 - - - 0.4026 0.9816 221125_WJC_METTL3_EV_vs_WT_F03.06831.06831.2 1.52 12-Jul R.LQDIEER[166.11].L "sp|Q96IZ5|RBM41_HUMAN,sp|O60231|DHX16_HUMAN,tr|A0A140T947|A0A140T947_HUMAN,tr|A2AB15|A2AB15_HUMAN,tr|H0Y6F9|H0Y6F9_HUMAN" 5 911.4588 1.48 25219 6831 2 911.458208 456.7367 RNA-binding protein 41 OS=Homo sapiens OX=9606 GN=RBM41 PE=1 SV=2 4.14 1857 - 2.45E+06 - - - -0.6287 - 1.3 0.051 - 173.8 1 2 0 -0.0006 7 0 0 0 1.63E+08 1.10E+08 - - - 0.2488 0.9615 221125_WJC_METTL3_EV_vs_WT_F03.06835.06835.2 4.92 12-Jun K.EGEMTLK.S "sp|P25789|PSA4_HUMAN,tr|H0YKS0|H0YKS0_HUMAN,tr|H0YKT8|H0YKT8_HUMAN,tr|H0YMI6|H0YMI6_HUMAN,tr|H0YMA1|H0YMA1_HUMAN,tr|H0YL69|H0YL69_HUMAN,tr|H0YN18|H0YN18_HUMAN,tr|H0YMZ1|H0YMZ1_HUMAN" 8 806.3844 1.38 25221 6835 2 806.382933 404.1995 Proteasome subunit alpha type-4 OS=Homo sapiens OX=9606 GN=PSMA4 PE=1 SV=1 4.53 1857.5 - 1.86E+06 - - - -1.8254 - 1.2 0.071 - 216.3 1 2 0 -0.0015 7 0 0 0 5.42E+07 3.92E+07 - - - 0.1426 0.9889 221125_WJC_METTL3_EV_vs_WT_F03.06837.06837.2 0.281 12-Aug R.LQDIEER.L "sp|Q96IZ5|RBM41_HUMAN,sp|O60231|DHX16_HUMAN,tr|A0A140T947|A0A140T947_HUMAN,tr|A2AB15|A2AB15_HUMAN,tr|H0Y6F9|H0Y6F9_HUMAN" 5 901.4505 1.5 25222 6837 2 901.449003 451.7325 RNA-binding protein 41 OS=Homo sapiens OX=9606 GN=RBM41 PE=1 SV=2 4.14 1857.7 - 4.17E+06 - - - -1.6729 - 1.574 0.06 - 242.3 1 2 0 -0.0015 7 0 0 0 1.63E+08 1.08E+08 - - - 0.921 0.9114 221125_WJC_METTL3_EV_vs_WT_F03.06838.06838.2 4.72 12-Jul R.EALEYQR.Q "sp|Q8TAQ2|SMRC2_HUMAN,tr|F8VXC8|F8VXC8_HUMAN" 2 907.4399 6.07 25223 6838 2 907.438151 454.7272 SWI\SNF complex subunit SMARCC2 OS=Homo sapiens OX=9606 GN=SMARCC2 PE=1 SV=1 4.53 1857.8 - 1.10E+06 - - - -1.9781 - 0.999 0.083 - 110.5 1 2 0 -0.0018 7 0 0 0 1.39E+08 2.29E+07 - - - -0.3497 0.9984 221125_WJC_METTL3_EV_vs_WT_F03.06862.06862.2 0.00758 16-Aug R.EVYEEAGVK[136.11].G "sp|Q8NFP7|NUD10_HUMAN,sp|Q96G61|NUD11_HUMAN,sp|Q9NZJ9|NUDT4_HUMAN,sp|A0A024RBG1|NUD4B_HUMAN,tr|A0A0C4DGJ4|A0A0C4DGJ4_HUMAN,tr|F8VRL4|F8VRL4_HUMAN,tr|F8VRR0|F8VRR0_HUMAN" 7 1030.5062 0.94 25231 6862 2 1030.505474 516.2604 Diphosphoinositol polyphosphate phosphohydrolase 3-alpha OS=Homo sapiens OX=9606 GN=NUDT10 PE=1 SV=1 4.25 1860.9 - 531534 - - - -0.7443 - 1.184 0.339 - 168.6 1 2 0 -0.0008 9 0 0 0 1.14E+08 1.21E+08 - - - 2.0332 0.9984 221125_WJC_METTL3_EV_vs_WT_F03.06869.06869.2 0.0937 12-Jul K.FDSEYER[166.11].M "sp|P43243|MATR3_HUMAN,tr|A8MXP9|A8MXP9_HUMAN,tr|D6R991|D6R991_HUMAN,tr|A0A0R4J2E8|A0A0R4J2E8_HUMAN,tr|H0Y8T4|H0Y8T4_HUMAN,tr|D6REM6|D6REM6_HUMAN" 6 954.3958 1.32 25232 6869 2 954.393068 478.2052 Matrin-3 OS=Homo sapiens OX=9606 GN=MATR3 PE=1 SV=2 4.14 1862 - 8.40E+07 - - - -2.9107 - 1.603 0.378 - 149.8 1 2 0 -0.0028 7 0 0 0 5.23E+09 3.96E+09 - - - 3.3272 0.9204 221125_WJC_METTL3_EV_vs_WT_F03.06873.06873.2 0.2 16-Aug K.IIDGAPC[160.03]AR.G sp|P49862|KLK7_HUMAN 1 971.4859 34.51 25234 6873 2 971.482628 486.7502 Kallikrein-7 OS=Homo sapiens OX=9606 GN=KLK7 PE=1 SV=1 5.83 1862.6 - 3.99E+06 - - - -3.3176 - 1.277 0.081 - 107.6 1 2 0 -0.0032 9 0 0 0 1.72E+08 4.98E+06 - - - 0.3456 0.9734 221125_WJC_METTL3_EV_vs_WT_F03.06884.06884.2 0.117 14-Sep R.ALQASALK[136.11].A "sp|P04075|ALDOA_HUMAN,tr|H3BR68|H3BR68_HUMAN,tr|H3BQN4|H3BQN4_HUMAN,tr|J3KPS3|J3KPS3_HUMAN" 4 808.4898 1.01 25237 6884 2 808.487025 405.2522 Fructose-bisphosphate aldolase A OS=Homo sapiens OX=9606 GN=ALDOA PE=1 SV=2 8.8 1864.1 - 1.49E+06 - - - -3.436 - 1.65 0.087 - 227 1 2 0 -0.0028 8 0 0 0 3.58E+08 3.55E+08 - - - 1.193 0.9858 221125_WJC_METTL3_EV_vs_WT_F03.06893.06893.2 1.54 14-Jul R.ALQASALK.A "sp|P04075|ALDOA_HUMAN,tr|H3BR68|H3BR68_HUMAN,tr|H3BQN4|H3BQN4_HUMAN,tr|J3KPS3|J3KPS3_HUMAN" 4 800.4756 1.25 25240 6893 2 800.473303 401.2451 Fructose-bisphosphate aldolase A OS=Homo sapiens OX=9606 GN=ALDOA PE=1 SV=2 8.8 1865.3 - 3.14E+06 - - - -2.8733 - 1.289 0.21 - 152.2 1 2 0 -0.0023 8 0 0 0 3.57E+08 2.85E+08 - - - 1.357 0.9978 221125_WJC_METTL3_EV_vs_WT_F03.06912.06912.2 0.381 14-Sep K.LAQLEEAK.Q "sp|P24539|AT5F1_HUMAN,tr|Q5QNZ2|Q5QNZ2_HUMAN" 2 900.4916 1.29 25244 6912 2 900.490243 451.2531 "ATP synthase F(0) complex subunit B1, mitochondrial OS=Homo sapiens OX=9606 GN=ATP5PB PE=1 SV=2" 4.53 1868.1 - 2.30E+06 - - - -1.5591 - 1.743 0.19 - 257.8 1 2 0 -0.0014 8 0 0 0 3.93E+08 3.04E+08 - - - 2.1196 0.9896 221125_WJC_METTL3_EV_vs_WT_F03.06913.06913.2 0.823 14-Nov K.QAILAAQR[166.11].R sp|O60869|EDF1_HUMAN 1 879.5166 2.28 25245 6913 2 879.516313 440.7656 Endothelial differentiation-related factor 1 OS=Homo sapiens OX=9606 GN=EDF1 PE=1 SV=1 9.75 1868.2 - 1.39E+06 - - - -0.2922 - 1.425 0.065 - 293.3 1 2 0 -0.0003 8 0 0 0 3.26E+08 1.43E+08 - - - 0.5892 0.9988 221125_WJC_METTL3_EV_vs_WT_F03.06915.06915.2 0.392 20-Aug K.VMATTGGTNLR.D sp|P26196|DDX6_HUMAN 1 1119.5706 1.02 25247 6915 2 1119.56777 560.7926 Probable ATP-dependent RNA helicase DDX6 OS=Homo sapiens OX=9606 GN=DDX6 PE=1 SV=2 9.72 1868.4 - 896356 - - - -2.5662 - 1.956 0.342 - 144.3 1 2 0 -0.0029 11 0 0 0 1.27E+08 1.24E+08 - - - 3.3811 0.9992 221125_WJC_METTL3_EV_vs_WT_F03.06918.06918.2 2.04E-05 20-Oct K.VMATTGGTNLR[166.11].D sp|P26196|DDX6_HUMAN 1 1129.5789 1.02 25248 6918 2 1129.575401 565.7967 Probable ATP-dependent RNA helicase DDX6 OS=Homo sapiens OX=9606 GN=DDX6 PE=1 SV=2 9.72 1868.8 - 912338 - - - -3.1091 - 1.847 0.486 - 311 1 2 0 -0.0035 11 0 0 0 1.27E+08 1.24E+08 - - - 4.2893 0.9733 221125_WJC_METTL3_EV_vs_WT_F03.06920.06920.2 0.00918 20-Oct F.VLAPEGSVANK[136.11].F "sp|Q13283|G3BP1_HUMAN,tr|A0A7I2V5M7|A0A7I2V5M7_HUMAN,tr|A0A7P0P2U7|A0A7P0P2U7_HUMAN,tr|A0A7I2YQU8|A0A7I2YQU8_HUMAN,tr|A0A7I2V651|A0A7I2V651_HUMAN,tr|A0A7I2YQN9|A0A7I2YQN9_HUMAN,tr|A0A7I2V2V1|A0A7I2V2V1_HUMAN" 7 1091.6066 1.25 25249 6920 2 1091.605625 546.8106 Ras GTPase-activating protein-binding protein 1 OS=Homo sapiens OX=9606 GN=G3BP1 PE=1 SV=1 5.97 1869 - 1.43E+06 - - - -0.9152 - 1.861 0.345 - 363.9 1 1 0 -0.001 11 0 0 0 4.90E+08 3.92E+08 - - - 3.2691 0.9923 221125_WJC_METTL3_EV_vs_WT_F03.06924.06924.2 0.304 16-Aug K.LEGDAALNR[166.11].L sp|Q9Y2Z0|SGT1_HUMAN 1 967.4962 1.55 25251 6924 2 967.496711 484.7554 Protein SGT1 homolog OS=Homo sapiens OX=9606 GN=SUGT1 PE=1 SV=3 4.37 1869.5 - 742482 - - - 0.4982 - 1.431 0.124 - 111.7 2 2 0 0.0005 9 0 0 0 4.39E+07 2.83E+07 - - - 0.859 0.93 221125_WJC_METTL3_EV_vs_WT_F03.06933.06933.2 0.0817 12-Jul R.GINTLER.S "sp|P52732|KIF11_HUMAN,tr|A0A7I2V3A9|A0A7I2V3A9_HUMAN" 2 801.4345 4.34 25255 6933 2 801.432244 401.7245 Kinesin-like protein KIF11 OS=Homo sapiens OX=9606 GN=KIF11 PE=1 SV=2 6 1870.6 - 1.31E+07 - - - -2.7738 - 1.431 0 - 180.6 1 2 0 -0.0022 7 0 0 0 4.25E+09 9.80E+08 - - - 0.1758 0.991 221125_WJC_METTL3_EV_vs_WT_F03.06934.06934.2 0.857 12-Jul R.GATELYR[166.11].T sp|Q7LGA3|HS2ST_HUMAN 1 818.4162 0.94 25256 6934 2 818.414206 410.2154 Heparan sulfate 2-O-sulfotransferase 1 OS=Homo sapiens OX=9606 GN=HS2ST1 PE=1 SV=1 6 1870.7 - 3.71E+06 - - - -2.4218 - 1.316 0.209 - 175.8 1 2 0 -0.002 7 0 0 0 2.63E+08 2.80E+08 - - - 1.4541 0.89 221125_WJC_METTL3_EV_vs_WT_F03.06941.06941.2 1.82 12-Jun R.GINTLER[166.11].S "sp|P52732|KIF11_HUMAN,tr|A0A7I2V3A9|A0A7I2V3A9_HUMAN" 2 811.4427 4.34 25260 6941 2 811.440925 406.7286 Kinesin-like protein KIF11 OS=Homo sapiens OX=9606 GN=KIF11 PE=1 SV=2 6 1871.5 - 5.74E+06 - - - -2.2331 - 1.198 0 - 123.2 1 2 0 -0.0018 7 0 0 0 4.25E+09 9.80E+08 - - - -0.3872 0.9605 221125_WJC_METTL3_EV_vs_WT_F03.06951.06951.2 0.00223 14-Aug K.ETGYVVER.P "sp|Q9NYF8|BCLF1_HUMAN,tr|E9PKI6|E9PKI6_HUMAN,tr|A0A1W2PQ43|A0A1W2PQ43_HUMAN,tr|E9PK91|E9PK91_HUMAN,tr|E9PK09|E9PK09_HUMAN,tr|E9PQN2|E9PQN2_HUMAN" 6 951.4662 2.11 25264 6951 2 951.464713 476.7404 Bcl-2-associated transcription factor 1 OS=Homo sapiens OX=9606 GN=BCLAF1 PE=1 SV=2 4.53 1872.8 - 2.34E+06 - - - -1.5219 - 1.646 0.355 - 242 1 1 0 -0.0014 8 0 0 0 4.87E+08 2.31E+08 - - - 3.1656 0.9996 221125_WJC_METTL3_EV_vs_WT_F03.06959.06959.2 0.000427 18-Oct K.AGFAGDDAPR.A "sp|Q6S8J3|POTEE_HUMAN,sp|P63261|ACTG_HUMAN,sp|P68133|ACTS_HUMAN,sp|P62736|ACTA_HUMAN,sp|P68032|ACTC_HUMAN,sp|P60709|ACTB_HUMAN,sp|P63267|ACTH_HUMAN,sp|A5A3E0|POTEF_HUMAN,sp|P0CG38|POTEI_HUMAN,sp|P0CG39|POTEJ_HUMAN,tr|A0A804GS07|A0A804GS07_HUMAN,tr|I3L3I0|I3L3I0_HUMAN,tr|G5E9R0|G5E9R0_HUMAN,tr|E7EVS6|E7EVS6_HUMAN,tr|A0A6Q8PGD7|A0A6Q8PGD7_HUMAN,tr|B8ZZJ2|B8ZZJ2_HUMAN,tr|J3KT65|J3KT65_HUMAN,tr|I3L3R2|I3L3R2_HUMAN,tr|K7EM38|K7EM38_HUMAN,tr|F6QUT6|F6QUT6_HUMAN,tr|C9JTX5|C9JTX5_HUMAN,tr|A0A6Q8PH58|A0A6Q8PH58_HUMAN,tr|F6UVQ4|F6UVQ4_HUMAN,tr|F8WB63|F8WB63_HUMAN,tr|I3L1U9|I3L1U9_HUMAN,tr|A0A2R8Y793|A0A2R8Y793_HUMAN,tr|I3L4N8|I3L4N8_HUMAN,tr|C9JUM1|C9JUM1_HUMAN,tr|F8WCH0|F8WCH0_HUMAN,tr|C9JZR7|C9JZR7_HUMAN,tr|C9JFL5|C9JFL5_HUMAN,tr|A0A2R8YGF8|A0A2R8YGF8_HUMAN,tr|A6NL76|A6NL76_HUMAN,tr|A0A7P0TBL1|A0A7P0TBL1_HUMAN" 34 975.441 1.03 25266 6959 2 975.43924 488.7278 POTE ankyrin domain family member E OS=Homo sapiens OX=9606 GN=POTEE PE=2 SV=3 4.21 1874 - 1.42E+07 - - - -1.8135 - 1.705 0.459 - 268.6 1 2 0 -0.0018 10 0 0 0 2.42E+09 2.35E+09 - - - 3.92 0.9998 221125_WJC_METTL3_EV_vs_WT_F03.06963.06963.2 0.00123 18-Oct K.AGFAGDDAPR[166.11].A "sp|Q6S8J3|POTEE_HUMAN,sp|P63261|ACTG_HUMAN,sp|P68133|ACTS_HUMAN,sp|P62736|ACTA_HUMAN,sp|P68032|ACTC_HUMAN,sp|P60709|ACTB_HUMAN,sp|P63267|ACTH_HUMAN,sp|A5A3E0|POTEF_HUMAN,sp|P0CG38|POTEI_HUMAN,sp|P0CG39|POTEJ_HUMAN,tr|A0A804GS07|A0A804GS07_HUMAN,tr|I3L3I0|I3L3I0_HUMAN,tr|G5E9R0|G5E9R0_HUMAN,tr|E7EVS6|E7EVS6_HUMAN,tr|A0A6Q8PGD7|A0A6Q8PGD7_HUMAN,tr|B8ZZJ2|B8ZZJ2_HUMAN,tr|J3KT65|J3KT65_HUMAN,tr|I3L3R2|I3L3R2_HUMAN,tr|K7EM38|K7EM38_HUMAN,tr|F6QUT6|F6QUT6_HUMAN,tr|C9JTX5|C9JTX5_HUMAN,tr|A0A6Q8PH58|A0A6Q8PH58_HUMAN,tr|F6UVQ4|F6UVQ4_HUMAN,tr|F8WB63|F8WB63_HUMAN,tr|I3L1U9|I3L1U9_HUMAN,tr|A0A2R8Y793|A0A2R8Y793_HUMAN,tr|I3L4N8|I3L4N8_HUMAN,tr|C9JUM1|C9JUM1_HUMAN,tr|F8WCH0|F8WCH0_HUMAN,tr|C9JZR7|C9JZR7_HUMAN,tr|C9JFL5|C9JFL5_HUMAN,tr|A0A2R8YGF8|A0A2R8YGF8_HUMAN,tr|A6NL76|A6NL76_HUMAN,tr|A0A7P0TBL1|A0A7P0TBL1_HUMAN" 34 985.4493 1.03 25268 6963 2 985.447778 493.7319 POTE ankyrin domain family member E OS=Homo sapiens OX=9606 GN=POTEE PE=2 SV=3 4.21 1874.5 - 2.22E+07 - - - -1.5232 - 1.876 0.512 - 236 1 2 0 -0.0015 10 0 0 0 2.42E+09 2.35E+09 - - - 4.5783 0.9982 221125_WJC_METTL3_EV_vs_WT_F03.06965.06965.2 0.302 14-Sep R.VGQAVALR[166.11].A "sp|Q13363|CTBP1_HUMAN,tr|H0Y9M9|H0Y9M9_HUMAN,tr|D6RAX2|D6RAX2_HUMAN,tr|H0Y8W7|H0Y8W7_HUMAN" 4 822.4951 0.89 25269 6965 2 822.49378 412.2548 C-terminal-binding protein 1 OS=Homo sapiens OX=9606 GN=CTBP1 PE=1 SV=2 9.72 1874.7 - 1.51E+06 - - - -1.6134 - 1.834 0.195 - 283.3 1 2 0 -0.0013 8 0 0 0 5.53E+07 6.23E+07 - - - 2.31 0.999 221125_WJC_METTL3_EV_vs_WT_F03.06971.06971.2 0.00104 16-Nov R.TPAQAAFEK[136.11].M "sp|Q9Y421|FA32A_HUMAN,tr|K7ENN5|K7ENN5_HUMAN,tr|K7EIY1|K7EIY1_HUMAN,tr|K7ELZ8|K7ELZ8_HUMAN" 4 969.5011 1.22 25271 6971 2 969.498351 485.7578 Protein FAM32A OS=Homo sapiens OX=9606 GN=FAM32A PE=1 SV=2 5.66 1875.5 - 915327 - - - -2.8314 - 1.851 0.396 - 414.9 1 2 0 -0.0027 9 0 0 0 1.94E+08 1.60E+08 - - - 3.7463 0.9967 221125_WJC_METTL3_EV_vs_WT_F03.06978.06978.2 0.0601 14-Jul K.VISELNGK[136.11].N "sp|P05387|RLA2_HUMAN,tr|H0YDD8|H0YDD8_HUMAN" 2 866.4953 1.18 25272 6978 2 866.494229 434.2549 60S acidic ribosomal protein P2 OS=Homo sapiens OX=9606 GN=RPLP2 PE=1 SV=1 5.97 1876.6 - 2.83E+06 - - - -1.2164 - 1.19 0.279 - 103.4 1 2 0 -0.0011 8 0 0 0 1.07E+10 9.03E+09 - - - 1.626 0.9825 221125_WJC_METTL3_EV_vs_WT_F03.06981.06981.2 0.252 12-Jun K.VVFEQTK[136.11].V "sp|P60174|TPIS_HUMAN,tr|U3KQF3|U3KQF3_HUMAN,tr|U3KPZ0|U3KPZ0_HUMAN" 3 857.4738 0.07 25273 6981 2 857.472594 429.7442 Triosephosphate isomerase OS=Homo sapiens OX=9606 GN=TPI1 PE=1 SV=4 5.97 1876.9 - 5.07E+06 - - - -1.4286 - 1.106 0.155 - 95.2 1 2 0 -0.0012 7 0 0 0 3.06E+08 4.51E+09 - - - 0.5047 0.9698 221125_WJC_METTL3_EV_vs_WT_F03.06986.06986.2 0.657 12-Jul R.VEEIMEK.S "sp|O75688|PPM1B_HUMAN,tr|B8ZZF0|B8ZZF0_HUMAN,tr|A0A3B3IS24|A0A3B3IS24_HUMAN,tr|C9JIR6|C9JIR6_HUMAN" 4 876.4263 2.98 25275 6986 2 876.424694 439.2204 Protein phosphatase 1B OS=Homo sapiens OX=9606 GN=PPM1B PE=1 SV=1 4.25 1877.6 - 2.80E+06 - - - -1.7982 - 1.091 0.132 - 107.3 1 2 0 -0.0016 7 0 0 0 2.94E+09 9.87E+08 - - - 0.2914 0.9683 221125_WJC_METTL3_EV_vs_WT_F03.06993.06993.2 4.42 14-Jun K.LQVMANSR[166.11].N "sp|Q15046|SYK_HUMAN,tr|H3BVA8|H3BVA8_HUMAN" 2 927.4836 1.94 25278 6993 2 927.484345 464.7491 Lysine--tRNA ligase OS=Homo sapiens OX=9606 GN=KARS1 PE=1 SV=3 9.75 1878.4 - 795117 - - - 0.8507 - 1.216 0.049 - 110.1 1 2 0 0.0008 8 0 0 0 1.51E+09 7.77E+08 - - - -0.0075 0.9402 221125_WJC_METTL3_EV_vs_WT_F03.07002.07002.2 0.058 20-Oct F.VLAPEGSVANK.F "sp|Q13283|G3BP1_HUMAN,tr|A0A7I2V5M7|A0A7I2V5M7_HUMAN,tr|A0A7P0P2U7|A0A7P0P2U7_HUMAN,tr|A0A7I2YQU8|A0A7I2YQU8_HUMAN,tr|A0A7I2V651|A0A7I2V651_HUMAN,tr|A0A7I2YQN9|A0A7I2YQN9_HUMAN,tr|A0A7I2V2V1|A0A7I2V2V1_HUMAN" 7 1083.5924 1.25 25282 7002 2 1083.591405 542.8035 Ras GTPase-activating protein-binding protein 1 OS=Homo sapiens OX=9606 GN=G3BP1 PE=1 SV=1 5.97 1879.5 - 4.79E+06 - - - -0.9404 - 1.749 0.258 - 334.1 1 1 0 -0.001 11 0 0 0 4.90E+08 3.92E+08 - - - 2.4586 0.9841 221125_WJC_METTL3_EV_vs_WT_F03.07003.07003.2 0.0274 12-Aug K.VQQLVPK[136.11].R "sp|O43707|ACTN4_HUMAN,tr|F5GXS2|F5GXS2_HUMAN,tr|H7C144|H7C144_HUMAN" 3 818.5105 1.22 25283 7003 2 818.509224 410.2625 Alpha-actinin-4 OS=Homo sapiens OX=9606 GN=ACTN4 PE=1 SV=2 8.72 1879.5 - 3.84E+06 - - - -1.6066 - 1.393 0.075 - 200.6 1 2 0 -0.0013 7 0 0 0 1.68E+08 1.38E+08 - - - 0.6448 0.9992 221125_WJC_METTL3_EV_vs_WT_F03.07004.07004.2 0.00346 14-Jun K.ALASSGFK[136.11].Y sp|Q8IU81|I2BP1_HUMAN 1 787.432 1.23 25284 7004 2 787.431426 394.7233 Interferon regulatory factor 2-binding protein 1 OS=Homo sapiens OX=9606 GN=IRF2BP1 PE=1 SV=1 8.8 1879.6 - 4.39E+06 - - - -0.6705 - 1.383 0.354 - 105.6 1 2 0 -0.0005 8 0 0 0 2.52E+08 2.05E+08 - - - 2.6334 0.9981 221125_WJC_METTL3_EV_vs_WT_F03.07005.07005.2 0.0431 12-Jun K.GTFPDAR.E "sp|Q15233|NONO_HUMAN,tr|A0A7I2V535|A0A7I2V535_HUMAN,tr|A0A7I2V4K9|A0A7I2V4K9_HUMAN,tr|A0A7P0MRW0|A0A7P0MRW0_HUMAN,tr|A0A7I2V5Y7|A0A7I2V5Y7_HUMAN" 5 762.3661 0.92 25285 7005 2 762.365512 382.1903 Non-POU domain-containing octamer-binding protein OS=Homo sapiens OX=9606 GN=NONO PE=1 SV=4 5.84 1879.6 - 2.78E+06 - - - -0.7096 - 1.306 0.27 - 141.7 1 2 0 -0.0005 7 0 0 0 2.88E+08 3.14E+08 - - - 1.881 0.9981 221125_WJC_METTL3_EV_vs_WT_F03.07006.07006.2 0.0429 16-Sep K.LQEMEGTVK.S sp|P35579|MYH9_HUMAN 1 1033.5114 0.95 25286 7006 2 1033.510641 517.763 Myosin-9 OS=Homo sapiens OX=9606 GN=MYH9 PE=1 SV=4 4.53 1879.7 - 2.18E+06 - - - -0.7305 - 1.571 0.212 - 170.5 1 2 0 -0.0008 9 0 0 0 2.40E+08 2.52E+08 - - - 1.9134 0.9833 221125_WJC_METTL3_EV_vs_WT_F03.07010.07010.2 0.052 12-Jun K.VVFEQTK.V "sp|P60174|TPIS_HUMAN,tr|U3KQF3|U3KQF3_HUMAN,tr|U3KPZ0|U3KPZ0_HUMAN" 3 849.4596 0.07 25288 7010 2 849.458564 425.7371 Triosephosphate isomerase OS=Homo sapiens OX=9606 GN=TPI1 PE=1 SV=4 5.97 1880.1 - 4.39E+06 - - - -1.242 - 0.953 0.214 - 125.9 1 2 0 -0.0011 7 0 0 0 3.07E+08 4.38E+09 - - - 0.4687 0.9996 221125_WJC_METTL3_EV_vs_WT_F03.07011.07011.2 0.312 16-Sep K.LQEMEGTVK[136.11].S sp|P35579|MYH9_HUMAN 1 1041.5256 0.95 25289 7011 2 1041.52484 521.7701 Myosin-9 OS=Homo sapiens OX=9606 GN=MYH9 PE=1 SV=4 4.53 1880.2 - 3.66E+06 - - - -0.7259 - 1.918 0.328 - 216.1 1 2 0 -0.0008 9 0 0 0 2.40E+08 2.52E+08 - - - 3.3476 0.9971 221125_WJC_METTL3_EV_vs_WT_F03.07012.07012.2 0.0521 14-Jun K.LMSTVDPK[136.11].L "sp|Q05519|SRS11_HUMAN,tr|Q5T760|Q5T760_HUMAN,tr|Q5T757|Q5T757_HUMAN" 3 897.4721 1.37 25290 7012 2 897.471502 449.7433 Serine\arginine-rich splicing factor 11 OS=Homo sapiens OX=9606 GN=SRSF11 PE=1 SV=1 5.84 1880.2 - 1.82E+06 - - - -0.6708 - 1.233 0.253 - 121.5 1 2 0 -0.0006 8 0 0 0 1.41E+08 1.02E+08 - - - 1.5412 0.9996 221125_WJC_METTL3_EV_vs_WT_F03.07018.07018.2 0.0386 16-Nov K.LTAVEGSMK[136.11].E sp|Q6P2E9|EDC4_HUMAN 1 942.4936 2.66 25293 7018 2 942.492621 472.2541 Enhancer of mRNA-decapping protein 4 OS=Homo sapiens OX=9606 GN=EDC4 PE=1 SV=1 6 1881 - 807015 - - - -1.0048 - 2.249 0.297 - 317.1 1 2 0 -0.0009 9 0 0 0 1.28E+08 4.82E+07 - - - 3.5791 0.9997 221125_WJC_METTL3_EV_vs_WT_F03.07020.07020.2 0.00657 16-Oct R.LATVVNDER.F sp|Q9HCS7|SYF1_HUMAN 1 1015.5298 1.34 25294 7020 2 1015.529408 508.7722 Pre-mRNA-splicing factor SYF1 OS=Homo sapiens OX=9606 GN=XAB2 PE=1 SV=2 4.37 1881.2 - 1.61E+06 - - - -0.4096 - 2.077 0.311 - 501.3 1 2 0 -0.0004 9 0 0 0 8.60E+07 6.40E+07 - - - 3.4525 0.9974 221125_WJC_METTL3_EV_vs_WT_F03.07026.07026.2 0.452 12-Jun R.VEEIMEK[136.11].S "sp|O75688|PPM1B_HUMAN,tr|B8ZZF0|B8ZZF0_HUMAN,tr|A0A3B3IS24|A0A3B3IS24_HUMAN,tr|C9JIR6|C9JIR6_HUMAN" 4 884.4405 2.98 25296 7026 2 884.44038 443.2275 Protein phosphatase 1B OS=Homo sapiens OX=9606 GN=PPM1B PE=1 SV=1 4.25 1882 - 1.64E+07 - - - -0.1018 - 1.567 0.15 - 124.1 1 2 0 -0.0001 7 0 0 0 2.94E+09 9.88E+08 - - - 1.5721 0.9989 221125_WJC_METTL3_EV_vs_WT_F03.07028.07028.2 0.117 16-Oct R.TPAQAAFEK.M "sp|Q9Y421|FA32A_HUMAN,tr|K7ENN5|K7ENN5_HUMAN,tr|K7EIY1|K7EIY1_HUMAN,tr|K7ELZ8|K7ELZ8_HUMAN" 4 961.4869 0.69 25298 7028 2 961.486103 481.7507 Protein FAM32A OS=Homo sapiens OX=9606 GN=FAM32A PE=1 SV=2 5.66 1882.1 - 4.98E+06 - - - -0.8248 - 1.894 0.2 - 303.1 1 2 0 -0.0008 9 0 0 0 1.89E+08 2.74E+08 - - - 2.3657 0.9972 221125_WJC_METTL3_EV_vs_WT_F03.07029.07029.2 0.103 12-Jul K.AEAIVYK.H sp|P82933|RT09_HUMAN 1 792.4382 0.78 25299 7029 2 792.437888 397.2264 "28S ribosomal protein S9, mitochondrial OS=Homo sapiens OX=9606 GN=MRPS9 PE=1 SV=2" 6.05 1882.2 - 2.53E+06 - - - -0.3369 - 1.49 0.168 - 277.9 1 2 0 -0.0003 7 0 0 0 1.14E+08 1.47E+08 - - - 1.5453 0.9995 221125_WJC_METTL3_EV_vs_WT_F03.07042.07042.2 0.00438 18-Oct K.SLAAEEEAAR[166.11].Q sp|Q15149|PLEC_HUMAN 1 1055.5123 1.95 25303 7042 2 1055.512918 528.7634 Plectin OS=Homo sapiens OX=9606 GN=PLEC PE=1 SV=3 4.25 1884 - 376768 - - - 0.6111 - 1.751 0.336 - 316.4 1 2 0 0.0006 10 0 0 0 3.90E+07 2.00E+07 - - - 3.0861 0.9998 221125_WJC_METTL3_EV_vs_WT_F03.07044.07044.2 0.0021 16-Sep K.VTYMEASAK[136.11].L "sp|P62070|RRAS2_HUMAN,tr|E9PK85|E9PK85_HUMAN" 2 1006.4885 0.34 25304 7044 2 1006.488297 504.2515 Ras-related protein R-Ras2 OS=Homo sapiens OX=9606 GN=RRAS2 PE=1 SV=1 5.97 1884.2 - 335512 - - - -0.1848 - 1.668 0.467 - 176.3 1 2 0 -0.0002 9 0 0 0 2.74E+06 8.02E+06 - - - 3.9704 0.9995 221125_WJC_METTL3_EV_vs_WT_F03.07050.07050.2 0.000982 14-Oct K.QGEEPLVR[166.11].L "sp|A0A1B0GTU1|ZC11B_HUMAN,sp|O75152|ZC11A_HUMAN,tr|E9PBY7|E9PBY7_HUMAN,tr|A0A1W2PPR9|A0A1W2PPR9_HUMAN,tr|A0A494C0C4|A0A494C0C4_HUMAN,tr|E9PQ61|E9PQ61_HUMAN" 6 936.4904 1.83 25308 7050 2 936.490077 469.2525 Zinc finger CCCH domain-containing protein 11B OS=Homo sapiens OX=9606 GN=ZC3H11B PE=4 SV=1 4.53 1885 - 1.06E+06 - - - -0.3609 - 1.569 0.357 - 289.2 1 2 0 -0.0003 8 0 0 0 1.01E+08 5.52E+07 - - - 3.0362 0.9967 221125_WJC_METTL3_EV_vs_WT_F03.07070.07070.2 0.0298 12-Jul R.EIVTYTK[136.11].E "sp|Q13409|DC1I2_HUMAN,tr|E7ET01|E7ET01_HUMAN,tr|E7ETL8|E7ETL8_HUMAN,tr|E7EV09|E7EV09_HUMAN,tr|E7ESD3|E7ESD3_HUMAN,tr|E7EQU2|E7EQU2_HUMAN,tr|E7EQL5|E7EQL5_HUMAN,tr|E7EMU4|E7EMU4_HUMAN" 8 860.4735 1.35 25318 7070 2 860.473754 431.244 Cytoplasmic dynein 1 intermediate chain 2 OS=Homo sapiens OX=9606 GN=DYNC1I2 PE=1 SV=3 6.1 1887.2 - 1.52E+06 - - - 0.3138 - 1.295 0.213 - 218.3 1 2 0 0.0003 7 0 0 0 6.22E+07 4.61E+07 - - - 1.4332 0.993 221125_WJC_METTL3_EV_vs_WT_F03.07079.07079.2 1.11 12-Jun R.LTDTLGR[166.11].L "sp|P35520|CBS_HUMAN,tr|H7C1W6|H7C1W6_HUMAN,tr|H7C2W0|H7C2W0_HUMAN,tr|H7C2H4|H7C2H4_HUMAN" 4 784.4318 0.49 25324 7079 2 784.431604 393.2232 Cystathionine beta-synthase OS=Homo sapiens OX=9606 GN=CBS PE=1 SV=2 5.84 1888.2 - 2.59E+06 - - - -0.2983 - 1.205 0.185 - 93.4 2 2 0 -0.0002 7 0 0 0 4.17E+07 8.48E+07 - - - 0.8637 0.9834 221125_WJC_METTL3_EV_vs_WT_F03.07081.07081.2 0.0092 16-Sep K.INAVVETGR[166.11].R "sp|Q01082|SPTB2_HUMAN,tr|A0A087WUZ3|A0A087WUZ3_HUMAN" 2 967.5326 4 25326 7081 2 967.5384 484.7736 "Spectrin beta chain, non-erythrocytic 1 OS=Homo sapiens OX=9606 GN=SPTBN1 PE=1 SV=2" 6 1888.4 - 730566 - - - 5.9802 - 2.162 0.256 - 249.5 1 2 0 0.0058 9 0 0 0 6.85E+07 1.71E+07 - - - 3.1606 0.999 221125_WJC_METTL3_EV_vs_WT_F03.07082.07082.2 0.0535 18-Jun R.IVEQDTMPPK.G "sp|O00571|DDX3X_HUMAN,sp|O15523|DDX3Y_HUMAN,tr|A0A2R8YFR4|A0A2R8YFR4_HUMAN,tr|A0A2R8YCW1|A0A2R8YCW1_HUMAN,tr|A0A2R8YDH3|A0A2R8YDH3_HUMAN,tr|A0A2R8YDT5|A0A2R8YDT5_HUMAN,tr|A0A2R8Y645|A0A2R8Y645_HUMAN,tr|A0A2R8YF78|A0A2R8YF78_HUMAN,tr|A0A0D9SFB3|A0A0D9SFB3_HUMAN,tr|A0A2R8YFS5|A0A2R8YFS5_HUMAN,tr|A0A0D9SF53|A0A0D9SF53_HUMAN,tr|A0A2R8Y5G6|A0A2R8Y5G6_HUMAN,tr|A0A2R8Y7T2|A0A2R8Y7T2_HUMAN,tr|A0A0D9SG12|A0A0D9SG12_HUMAN,tr|F6S8Q4|F6S8Q4_HUMAN,tr|A0A2U3TZJ9|A0A2U3TZJ9_HUMAN,tr|A0A2R8Y4A4|A0A2R8Y4A4_HUMAN" 17 1156.5798 1.21 25327 7082 2 1156.579974 579.2972 ATP-dependent RNA helicase DDX3X OS=Homo sapiens OX=9606 GN=DDX3X PE=1 SV=3 4.37 1888.5 - 150301 - - - 0.1418 - 1.288 0.353 - 78.1 1 2 0 0.0002 10 0 0 0 8.23E+06 6.83E+06 - - - 2.3547 0.9996 221125_WJC_METTL3_EV_vs_WT_F03.07085.07085.2 0.000249 18-Sep K.SLAAEEEAAR.Q sp|Q15149|PLEC_HUMAN 1 1045.504 1.6 25328 7085 2 1045.502734 523.7593 Plectin OS=Homo sapiens OX=9606 GN=PLEC PE=1 SV=3 4.25 1888.9 - 1.17E+06 - - - -1.2138 - 1.882 0.362 - 264.8 1 2 0 -0.0013 10 0 0 0 4.03E+07 2.53E+07 - - - 3.4794 0.9987 221125_WJC_METTL3_EV_vs_WT_F03.07086.07086.2 0.212 12-Jun K.FDSEYER.M "sp|P43243|MATR3_HUMAN,tr|A8MXP9|A8MXP9_HUMAN,tr|D6R991|D6R991_HUMAN,tr|A0A0R4J2E8|A0A0R4J2E8_HUMAN,tr|H0Y8T4|H0Y8T4_HUMAN,tr|D6REM6|D6REM6_HUMAN" 6 944.3876 1.55 25329 7086 2 944.389023 473.2011 Matrin-3 OS=Homo sapiens OX=9606 GN=MATR3 PE=1 SV=2 4.14 1889 - 837715 - - - 1.5322 - 1.102 0.441 - 86 1 2 0 0.0014 7 0 0 0 2.14E+07 1.38E+07 - - - 2.6055 0.9918 221125_WJC_METTL3_EV_vs_WT_F03.07091.07091.2 0.227 12-Jun R.LEDELNR.A "sp|P15924|DESP_HUMAN,sp|Q9UHC9|NPCL1_HUMAN,sp|O15118|NPC1_HUMAN,tr|A0A0C4DFX6|A0A0C4DFX6_HUMAN,tr|A0A0C4DGG6|A0A0C4DGG6_HUMAN,tr|K7EQ23|K7EQ23_HUMAN" 6 887.4349 30.38 25332 7091 2 887.434142 444.7247 Desmoplakin OS=Homo sapiens OX=9606 GN=DSP PE=1 SV=3 4.14 1889.5 - 1.23E+07 - - - -0.8102 - 1.484 0.073 - 134.6 1 2 0 -0.0007 7 0 0 0 1.15E+09 3.78E+07 - - - 0.8307 0.9769 221125_WJC_METTL3_EV_vs_WT_F03.07092.07092.2 0.27 12-Jun K.GTFPDAR[166.11].E "sp|Q15233|NONO_HUMAN,tr|A0A7I2V535|A0A7I2V535_HUMAN,tr|A0A7I2V4K9|A0A7I2V4K9_HUMAN,tr|A0A7P0MRW0|A0A7P0MRW0_HUMAN,tr|A0A7I2V5Y7|A0A7I2V5Y7_HUMAN" 5 772.3743 -1 25333 7092 2 772.370681 387.1944 Non-POU domain-containing octamer-binding protein OS=Homo sapiens OX=9606 GN=NONO PE=1 SV=4 5.84 1889.6 - 3.49E+06 - - - -4.7153 - 1.475 0.237 - 138.9 1 2 0 -0.0036 7 0 0 0 0.00E+00 0.00E+00 - - - 2.0218 0.9158 221125_WJC_METTL3_EV_vs_WT_F03.07098.07098.2 0.0581 18-Dec L.IAAQATALNR[166.11].G "sp|Q8IY67|RAVR1_HUMAN,tr|E9PAU2|E9PAU2_HUMAN,tr|A0A087WZ13|A0A087WZ13_HUMAN" 3 1037.5857 0.86 25336 7098 2 1037.584585 519.8001 Ribonucleoprotein PTB-binding 1 OS=Homo sapiens OX=9606 GN=RAVER1 PE=1 SV=1 9.75 1890.3 - 879823 - - - -1.0871 - 1.936 0.177 - 667.3 1 1 0 -0.0011 10 0 0 0 6.30E+07 7.36E+07 - - - 2.192 0.9814 221125_WJC_METTL3_EV_vs_WT_F03.07099.07099.2 0.00052 18-Nov L.IAAQATALNR.G "sp|Q8IY67|RAVR1_HUMAN,tr|E9PAU2|E9PAU2_HUMAN,tr|A0A087WZ13|A0A087WZ13_HUMAN" 3 1027.5774 0.86 25337 7099 2 1027.575557 514.796 Ribonucleoprotein PTB-binding 1 OS=Homo sapiens OX=9606 GN=RAVER1 PE=1 SV=1 9.75 1890.4 - 586400 - - - -1.8354 - 2.228 0.418 - 477.3 1 1 0 -0.0019 10 0 0 0 6.30E+07 7.36E+07 - - - 4.3639 0.9845 221125_WJC_METTL3_EV_vs_WT_F03.07103.07103.2 3.8 12-Jun K.EISAQIR[166.11].A "sp|P11586|C1TC_HUMAN,sp|Q9P086|MED11_HUMAN,tr|F5H2F4|F5H2F4_HUMAN,tr|I3L2Q0|I3L2Q0_HUMAN,tr|I3L3E8|I3L3E8_HUMAN,tr|V9GYY3|V9GYY3_HUMAN" 6 825.4584 1.61 25338 7103 2 825.457066 413.7365 "C-1-tetrahydrofolate synthase, cytoplasmic OS=Homo sapiens OX=9606 GN=MTHFD1 PE=1 SV=4" 6.1 1891 - 5.64E+06 - - - -1.6003 - 1.234 0.129 - 149.6 1 2 0 -0.0013 7 0 0 0 5.95E+08 3.68E+08 - - - 0.6596 0.996 221125_WJC_METTL3_EV_vs_WT_F03.07113.07113.2 0.0335 14-Aug K.LDPALQDK[136.11].C "sp|Q92896|GSLG1_HUMAN,tr|H3BM42|H3BM42_HUMAN" 2 906.4902 1.79 25343 7113 2 906.487185 454.2524 Golgi apparatus protein 1 OS=Homo sapiens OX=9606 GN=GLG1 PE=1 SV=2 4.21 1892.4 - 1.68E+06 - - - -3.3227 - 1.709 0.274 - 233.6 1 2 0 -0.003 8 0 0 0 1.47E+08 8.23E+07 - - - 2.6801 0.9979 221125_WJC_METTL3_EV_vs_WT_F03.07115.07115.2 0.219 14-Aug K.ALAPEYAK.A "sp|P07237|PDIA1_HUMAN,tr|A0A7P0TA97|A0A7P0TA97_HUMAN,tr|A0A7P0T8C0|A0A7P0T8C0_HUMAN,tr|H7BZ94|H7BZ94_HUMAN,tr|A0A7P0TA71|A0A7P0TA71_HUMAN,tr|I3L4M2|I3L4M2_HUMAN,tr|A0A7P0T9D6|A0A7P0T9D6_HUMAN,tr|H0Y3Z3|H0Y3Z3_HUMAN,tr|A0A7P0Z4S2|A0A7P0Z4S2_HUMAN,tr|I3NI03|I3NI03_HUMAN,tr|A0A7P0TA35|A0A7P0TA35_HUMAN,tr|A0A7P0TAX9|A0A7P0TAX9_HUMAN,tr|I3L514|I3L514_HUMAN,tr|A0A7P0Z476|A0A7P0Z476_HUMAN,tr|A0A7P0TBP8|A0A7P0TBP8_HUMAN,tr|A0A7P0TB26|A0A7P0TB26_HUMAN,tr|A0A7P0T9U6|A0A7P0T9U6_HUMAN,tr|I3L0S0|I3L0S0_HUMAN,tr|A0A7P0T8J3|A0A7P0T8J3_HUMAN,tr|A0A7P0Z4J0|A0A7P0Z4J0_HUMAN,tr|A0A7P0T9S9|A0A7P0T9S9_HUMAN,tr|A0A7P0T8X1|A0A7P0T8X1_HUMAN,tr|I3L3U6|I3L3U6_HUMAN" 23 861.4596 1.25 25344 7115 2 861.458249 431.7371 Protein disulfide-isomerase OS=Homo sapiens OX=9606 GN=P4HB PE=1 SV=3 6.05 1892.6 - 5.85E+06 - - - -1.5903 - 1.406 0.284 - 266.3 1 2 0 -0.0014 8 0 0 0 6.49E+08 5.20E+08 - - - 2.1659 0.9577 221125_WJC_METTL3_EV_vs_WT_F03.07116.07116.2 0.0336 16-Aug R.MLAQGVHPQ.H "sp|Q9NRA8|4ET_HUMAN,tr|B1AKL4|B1AKL4_HUMAN" 2 979.4909 - 25345 7116 2 979.490429 490.7527 Eukaryotic translation initiation factor 4E transporter OS=Homo sapiens OX=9606 GN=EIF4ENIF1 PE=1 SV=2 6.49 1892.7 - 327925 - - - -0.5176 - 1.572 0.315 - 136.4 1 1 0 -0.0005 9 0 0 0 - - - - - 2.6761 0.9499 221125_WJC_METTL3_EV_vs_WT_F03.07120.07120.2 0.352 14-Jul R.VYGGLTTK[136.11].V sp|Q8WUM4|PDC6I_HUMAN 1 845.4738 1.21 25346 7120 2 845.471328 423.7442 Programmed cell death 6-interacting protein OS=Homo sapiens OX=9606 GN=PDCD6IP PE=1 SV=1 8.56 1893.3 - 2.00E+06 - - - -2.9463 - 1.239 0.109 - 119 1 2 0 -0.0025 8 0 0 0 1.18E+08 9.75E+07 - - - 0.4916 0.9974 221125_WJC_METTL3_EV_vs_WT_F03.07121.07121.2 0.286 12-Jun R.YQEVLDK.Q "sp|Q8ND24|RN214_HUMAN,tr|E9PN76|E9PN76_HUMAN" 2 893.4494 2.34 25347 7121 2 893.448907 447.732 RING finger protein 214 OS=Homo sapiens OX=9606 GN=RNF214 PE=1 SV=2 4.37 1893.4 - 1.17E+06 - - - -0.6055 - 1.327 0.23 - 107.5 1 2 0 -0.0005 7 0 0 0 1.15E+08 4.89E+07 - - - 1.6361 0.9632 221125_WJC_METTL3_EV_vs_WT_F03.07133.07133.2 0.389 14-Jun K.GESGILGK.D sp|O43172|PRP4_HUMAN 1 759.4127 4.98 25351 7133 2 759.412383 380.7136 U4\U6 small nuclear ribonucleoprotein Prp4 OS=Homo sapiens OX=9606 GN=PRPF4 PE=1 SV=2 6 1894.9 - 2.54E+06 - - - -0.3766 - 1.217 0.047 - 152.6 3 2 0 -0.0003 8 0 0 0 2.09E+09 4.21E+08 - - - -0.2328 0.9859 221125_WJC_METTL3_EV_vs_WT_F03.07141.07141.2 0.645 12-Aug K.NYVEVTR.K sp|Q13505|MTX1_HUMAN 1 879.445 1.49 25353 7141 2 879.443095 440.7298 Metaxin-1 OS=Homo sapiens OX=9606 GN=MTX1 PE=1 SV=3 6 1896.1 - 1.75E+06 - - - -2.2014 - 1.324 0.146 - 343.6 1 2 0 -0.0019 7 0 0 0 6.80E+07 4.56E+07 - - - 1.008 0.9966 221125_WJC_METTL3_EV_vs_WT_F03.07159.07159.2 0.357 12-Jun R.QLDQLSR.L "sp|Q6P3W7|SCYL2_HUMAN,tr|F8VSC5|F8VSC5_HUMAN,tr|A0A0U1RQQ9|A0A0U1RQQ9_HUMAN" 3 858.4559 1.04 25360 7159 2 858.45493 430.2352 SCY1-like protein 2 OS=Homo sapiens OX=9606 GN=SCYL2 PE=1 SV=1 5.84 1898.3 - 1.34E+07 - - - -1.1649 - 1.389 0.201 - 203.7 1 2 0 -0.001 7 0 0 0 5.26E+08 5.06E+08 - - - 1.5664 0.9973 221125_WJC_METTL3_EV_vs_WT_F03.07165.07165.2 0.0094 14-Jul K.GESGILGK[136.11].D sp|O43172|PRP4_HUMAN 1 767.4269 4.67 25363 7165 2 767.425423 384.7207 U4\U6 small nuclear ribonucleoprotein Prp4 OS=Homo sapiens OX=9606 GN=PRPF4 PE=1 SV=2 6 1899 - 7.31E+06 - - - -1.8842 - 1.402 0.278 - 178.2 1 2 0 -0.0014 8 0 0 0 1.89E+09 4.05E+08 - - - 2.1129 0.9989 221125_WJC_METTL3_EV_vs_WT_F03.07167.07167.2 0.000235 14-Aug R.AYSNSIVR.S sp|Q9H1Z4|WDR13_HUMAN 1 908.4716 0.18 25364 7167 2 908.46904 455.2431 WD repeat-containing protein 13 OS=Homo sapiens OX=9606 GN=WDR13 PE=1 SV=2 8.79 1899.2 - 2.50E+06 - - - -2.7959 - 1.611 0.42 - 194.8 1 2 0 -0.0025 8 0 0 0 1.13E+08 6.13E+08 - - - 3.5805 0.9979 221125_WJC_METTL3_EV_vs_WT_F03.07168.07168.2 0.06 16-Aug R.LPPPADYNK.E "sp|P51116|FXR2_HUMAN,tr|I3L1Z2|I3L1Z2_HUMAN" 2 1013.5182 2.16 25365 7168 2 1013.51733 507.7664 Fragile X mental retardation syndrome-related protein 2 OS=Homo sapiens OX=9606 GN=FXR2 PE=1 SV=2 5.83 1899.4 - 828333 - - - -0.8544 - 1.177 0.318 - 199.6 1 2 0 -0.0009 9 0 0 0 6.11E+07 2.83E+07 - - - 1.861 0.9991 221125_WJC_METTL3_EV_vs_WT_F03.07174.07174.2 0.0562 18-Oct R.VLEEGSVEAR.T sp|Q96CT7|CC124_HUMAN 1 1087.551 0.85 25368 7174 2 1087.548522 544.7828 Coiled-coil domain-containing protein 124 OS=Homo sapiens OX=9606 GN=CCDC124 PE=1 SV=1 4.25 1900.1 - 1.00E+06 - - - -2.2353 - 2.011 0.327 - 200.1 1 2 0 -0.0024 10 0 0 0 4.09E+08 4.83E+08 - - - 3.4056 0.9823 221125_WJC_METTL3_EV_vs_WT_F03.07177.07177.2 0.979 14-Jul K.VLTPTQVK.N sp|P30086|PEBP1_HUMAN 1 884.5331 1.3 25369 7177 2 884.531379 443.2738 Phosphatidylethanolamine-binding protein 1 OS=Homo sapiens OX=9606 GN=PEBP1 PE=1 SV=3 8.72 1900.5 - 1.94E+06 - - - -1.966 - 1.25 0.138 - 131.9 1 2 0 -0.0017 8 0 0 0 1.44E+08 1.11E+08 - - - 0.7327 0.9996 221125_WJC_METTL3_EV_vs_WT_F03.07179.07179.2 0.022 18-Oct R.VLEEGSVEAR[166.11].T sp|Q96CT7|CC124_HUMAN 1 1097.5592 0.85 25370 7179 2 1097.558275 549.7869 Coiled-coil domain-containing protein 124 OS=Homo sapiens OX=9606 GN=CCDC124 PE=1 SV=1 4.25 1900.7 - 2.14E+06 - - - -0.8637 - 1.752 0.372 - 206.5 1 2 0 -0.0009 10 0 0 0 4.08E+08 4.82E+08 - - - 3.3535 0.9044 221125_WJC_METTL3_EV_vs_WT_F03.07184.07184.2 6.32 12-Jun R.NYLSQPR.L "sp|P21281|VATB2_HUMAN,tr|E5RGH6|E5RGH6_HUMAN,tr|H0YC04|H0YC04_HUMAN,tr|H0YAT8|H0YAT8_HUMAN" 4 876.4454 0.96 25373 7184 2 876.443876 439.23 "V-type proton ATPase subunit B, brain isoform OS=Homo sapiens OX=9606 GN=ATP6V1B2 PE=1 SV=3" 8.75 1901.4 - 799046 - - - -1.7 - 1.067 0.032 - 142.6 1 2 0 -0.0015 7 0 0 0 5.23E+07 5.45E+07 - - - -0.5176 0.9895 221125_WJC_METTL3_EV_vs_WT_F03.07186.07186.2 0.247 14-Jul K.VLTPTQVK[136.11].N sp|P30086|PEBP1_HUMAN 1 892.5473 1.31 25374 7186 2 892.54607 447.2809 Phosphatidylethanolamine-binding protein 1 OS=Homo sapiens OX=9606 GN=PEBP1 PE=1 SV=3 8.72 1901.6 - 1.79E+06 - - - -1.3982 - 1.201 0.169 - 134.8 1 2 0 -0.0012 8 0 0 0 1.44E+08 1.11E+08 - - - 0.8412 0.9585 221125_WJC_METTL3_EV_vs_WT_F03.07194.07194.2 0.253 12-Jun K.VVEELTR[166.11].L "sp|Q16531|DDB1_HUMAN,sp|P62166|NCS1_HUMAN,tr|A0A7P0TAK7|A0A7P0TAK7_HUMAN,tr|A0A7P0T870|A0A7P0T870_HUMAN,tr|A0A7P0TB30|A0A7P0TB30_HUMAN,tr|A0A7P0Z3Z5|A0A7P0Z3Z5_HUMAN,tr|A0A7P0Z4B9|A0A7P0Z4B9_HUMAN,tr|A0A7P0T965|A0A7P0T965_HUMAN" 8 854.4737 0.91 25376 7194 2 854.471557 428.2441 DNA damage-binding protein 1 OS=Homo sapiens OX=9606 GN=DDB1 PE=1 SV=1 4.53 1902.7 - 7.31E+06 - - - -2.5103 - 1.444 0.046 - 139.4 2 2 0 -0.0021 7 0 0 0 2.70E+08 2.95E+08 - - - 0.4098 0.9814 221125_WJC_METTL3_EV_vs_WT_F03.07196.07196.2 0.992 12-Aug K.IPQALEK.L "sp|Q13435|SF3B2_HUMAN,tr|E9PPJ0|E9PPJ0_HUMAN,tr|H0YCG1|H0YCG1_HUMAN,tr|E9PJ04|E9PJ04_HUMAN" 4 797.4647 0.92 25377 7196 2 797.462689 399.7396 Splicing factor 3B subunit 2 OS=Homo sapiens OX=9606 GN=SF3B2 PE=1 SV=2 6 1902.9 - 7.22E+06 - - - -2.5268 - 1.403 0.146 - 180.1 3 2 0 -0.002 7 0 0 0 5.00E+08 5.46E+08 - - - 0.9785 0.9964 221125_WJC_METTL3_EV_vs_WT_F03.07197.07197.2 0.0703 14-Sep R.LPSNTLDR[166.11].L sp|P78527|PRKDC_HUMAN 1 924.4904 2.01 25378 7197 2 924.488023 463.2525 DNA-dependent protein kinase catalytic subunit OS=Homo sapiens OX=9606 GN=PRKDC PE=1 SV=3 5.84 1903 - 1.47E+06 - - - -2.5874 - 1.78 0.206 - 285.4 1 2 0 -0.0024 8 0 0 0 1.91E+08 9.51E+07 - - - 2.3008 0.9602 221125_WJC_METTL3_EV_vs_WT_F03.07203.07203.2 0.459 12-Jul R.SLETYER[166.11].L sp|Q15906|VPS72_HUMAN 1 906.4322 1.13 25382 7203 2 906.430854 454.2234 Vacuolar protein sorting-associated protein 72 homolog OS=Homo sapiens OX=9606 GN=VPS72 PE=1 SV=1 4.53 1903.6 - 1.08E+06 - - - -1.5202 - 0.946 0.153 - 163.4 1 2 0 -0.0014 7 0 0 0 6.85E+07 6.05E+07 - - - -0.0053 0.9982 221125_WJC_METTL3_EV_vs_WT_F03.07211.07211.2 0.0373 14-Jul R.VLIGENEK[136.11].A "sp|P55265|DSRAD_HUMAN,tr|A0A3B3IRQ9|A0A3B3IRQ9_HUMAN,tr|A0A3B3ISU1|A0A3B3ISU1_HUMAN,tr|A0A7P0Z4K3|A0A7P0Z4K3_HUMAN,tr|A0A7P0Z4F9|A0A7P0Z4F9_HUMAN" 5 908.5058 0.91 25385 7211 2 908.503366 455.2602 Double-stranded RNA-specific adenosine deaminase OS=Homo sapiens OX=9606 GN=ADAR PE=1 SV=4 4.53 1904.6 - 2.02E+06 - - - -2.7309 - 1.539 0.364 - 141.8 1 2 0 -0.0025 8 0 0 0 2.53E+08 2.79E+08 - - - 3.029 0.9987 221125_WJC_METTL3_EV_vs_WT_F03.07213.07213.2 0.00314 16-Aug K.IGDTSVSYK[136.11].Y sp|P20700|LMNB1_HUMAN 1 976.4957 3.54 25386 7213 2 976.493846 489.2551 Lamin-B1 OS=Homo sapiens OX=9606 GN=LMNB1 PE=1 SV=2 5.83 1904.8 - 1.21E+06 - - - -1.874 - 1.622 0.315 - 126.9 1 2 0 -0.0018 9 0 0 0 2.58E+08 7.31E+07 - - - 2.7663 0.9823 221125_WJC_METTL3_EV_vs_WT_F03.07216.07216.2 0.745 12-Aug K.IPQALEK[136.11].L "sp|Q13435|SF3B2_HUMAN,tr|E9PPJ0|E9PPJ0_HUMAN,tr|H0YCG1|H0YCG1_HUMAN,tr|E9PJ04|E9PJ04_HUMAN" 4 805.4789 1.09 25387 7216 2 805.477696 403.7467 Splicing factor 3B subunit 2 OS=Homo sapiens OX=9606 GN=SF3B2 PE=1 SV=2 6 1905.2 - 8.15E+06 - - - -1.4997 - 1.453 0.07 - 189.2 3 2 0 -0.0012 7 0 0 0 4.60E+08 4.22E+08 - - - 0.5284 0.9994 221125_WJC_METTL3_EV_vs_WT_F03.07220.07220.2 0.0854 16-Aug R.AEPLNSVAH.- "sp|O95777|LSM8_HUMAN,tr|C9JIZ0|C9JIZ0_HUMAN" 2 936.4665 - 25389 7220 2 936.465367 469.2405 U6 snRNA-associated Sm-like protein LSm8 OS=Homo sapiens OX=9606 GN=LSM8 PE=1 SV=3 5.24 1905.7 - 1.62E+06 - - - -1.2045 - 1.485 0.395 - 271.3 1 2 0 -0.0011 9 0 0 0 - - - - - 3.1021 0.9806 221125_WJC_METTL3_EV_vs_WT_F03.07224.07224.2 0.354 12-Jun R.SLETYER.L sp|Q15906|VPS72_HUMAN 1 896.424 1.12 25391 7224 2 896.423462 449.2193 Vacuolar protein sorting-associated protein 72 homolog OS=Homo sapiens OX=9606 GN=VPS72 PE=1 SV=1 4.53 1906.2 - 1.72E+06 - - - -0.5578 - 1.124 0.107 - 139.3 1 2 0 -0.0005 7 0 0 0 6.57E+07 5.89E+07 - - - 0.2015 0.9997 221125_WJC_METTL3_EV_vs_WT_F03.07225.07225.2 0.000141 24-Nov K.GPGEVAGTVTGQK[136.11].R "sp|Q86U44|MTA70_HUMAN,tr|F5H6D8|F5H6D8_HUMAN,tr|H0YFV6|H0YFV6_HUMAN,tr|B4DTN4|B4DTN4_HUMAN" 4 1207.6288 0 25392 7225 2 1207.629891 604.8217 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 6 1906.3 - 302658 - - - 0.8902 - 1.925 0.41 - 190.8 1 2 0 0.0011 13 0 0 0 3.04E+05 2.10E+08 - - - 3.7498 0.9456 221125_WJC_METTL3_EV_vs_WT_F03.07226.07226.2 2.4 12-Jul R.VLQDQLK[136.11].T sp|Q8NBJ4|GOLM1_HUMAN 1 850.5004 1.58 25393 7226 2 850.498822 426.2575 Golgi membrane protein 1 OS=Homo sapiens OX=9606 GN=GOLM1 PE=1 SV=1 5.81 1906.3 - 2.74E+06 - - - -1.8178 - 1.133 0.064 - 126.5 1 2 0 -0.0015 7 0 0 0 1.78E+08 1.12E+08 - - - -0.0911 0.9986 221125_WJC_METTL3_EV_vs_WT_F03.07229.07229.2 0.366 16-Jun K.VAEQVGIDR.G sp|Q13492|PICAL_HUMAN 1 985.5193 6.99 25394 7229 2 985.518777 493.7669 Phosphatidylinositol-binding clathrin assembly protein OS=Homo sapiens OX=9606 GN=PICALM PE=1 SV=2 4.37 1906.7 - 1.45E+06 - - - -0.4891 - 1.704 0.207 - 94.9 1 2 0 -0.0005 9 0 0 0 7.19E+07 1.03E+07 - - - 2.1117 0.9508 221125_WJC_METTL3_EV_vs_WT_F03.07230.07230.2 2.13 14-May R.LGQQPLPR[166.11].R sp|Q8N726|ARF_HUMAN 1 917.5322 0.35 25395 7230 2 917.531578 459.7734 Tumor suppressor ARF OS=Homo sapiens OX=9606 GN=CDKN2A PE=1 SV=2 9.75 1906.8 - 1.22E+06 - - - -0.6997 - 1.039 0.099 - 60.6 4 2 0 -0.0006 8 0 0 0 2.55E+07 7.27E+07 - - - -0.3815 0.9881 221125_WJC_METTL3_EV_vs_WT_F03.07233.07233.2 0.252 14-Jul R.LVEIDNGK.Q "sp|P02545|LMNA_HUMAN,tr|A0A6Q8PF80|A0A6Q8PF80_HUMAN,tr|A0A804HL68|A0A804HL68_HUMAN,tr|Q5TCI8|Q5TCI8_HUMAN,tr|A0A6Q8PFJ0|A0A6Q8PFJ0_HUMAN,tr|A0A6Q8PHQ9|A0A6Q8PHQ9_HUMAN,tr|Q3BDU5|Q3BDU5_HUMAN" 7 886.476 1.31 25396 7233 2 886.473222 444.2453 Prelamin-A\C OS=Homo sapiens OX=9606 GN=LMNA PE=1 SV=1 4.37 1907.2 - 3.28E+06 - - - -3.1304 - 1.388 0.218 - 143.1 1 2 0 -0.0028 8 0 0 0 1.07E+08 8.15E+07 - - - 1.6391 0.9995 221125_WJC_METTL3_EV_vs_WT_F03.07235.07235.2 0.0909 16-Oct R.VAVQGDVVR[166.11].E "sp|P07814|SYEP_HUMAN,tr|V9GYZ6|V9GYZ6_HUMAN" 2 951.5377 0.76 25397 7235 2 951.537162 476.7761 Bifunctional glutamate\proline--tRNA ligase OS=Homo sapiens OX=9606 GN=EPRS1 PE=1 SV=5 5.81 1907.4 - 1.02E+06 - - - -0.5654 - 1.899 0.285 - 363.9 1 2 0 -0.0005 9 0 0 0 3.32E+08 4.38E+08 - - - 3.0012 0.9741 221125_WJC_METTL3_EV_vs_WT_F03.07246.07246.2 0.477 14-Jul R.VEEAIVAR[166.11].L sp|Q15050|RRS1_HUMAN 1 895.5003 1.4 25402 7246 2 895.496433 448.7574 Ribosome biogenesis regulatory protein homolog OS=Homo sapiens OX=9606 GN=RRS1 PE=1 SV=2 4.53 1908.8 - 2.00E+06 - - - -4.2647 - 1.408 0.216 - 118.1 1 2 0 -0.0038 8 0 0 0 9.28E+07 6.65E+07 - - - 1.6671 0.999 221125_WJC_METTL3_EV_vs_WT_F03.07259.07259.2 0.644 12-Sep R.C[160.03]LDMEGR.L "sp|Q4VCS5|AMOT_HUMAN,tr|A6NP16|A6NP16_HUMAN,tr|E7ERM3|E7ERM3_HUMAN" 3 879.3579 1.29 25408 7259 2 879.356067 440.6862 Angiomotin OS=Homo sapiens OX=9606 GN=AMOT PE=1 SV=1 4.37 1910.4 - 623442 - - - -2.0538 - 1.466 0.387 - 209.3 1 2 0 -0.0018 7 0 0 0 1.91E+07 1.48E+07 - - - 3.1109 0.9114 221125_WJC_METTL3_EV_vs_WT_F03.07260.07260.2 1.67 12-May R.ENADIIR.E "sp|Q5T9A4|ATD3B_HUMAN,sp|Q9NVI7|ATD3A_HUMAN" 2 829.4294 3.64 25409 7260 2 829.430922 415.722 ATPase family AAA domain-containing protein 3B OS=Homo sapiens OX=9606 GN=ATAD3B PE=1 SV=1 4.37 1910.4 - 4.44E+06 - - - 1.8579 - 1.01 0.078 - 97.9 1 2 0 0.0015 7 0 0 0 2.09E+09 5.74E+08 - - - -0.3518 0.9993 221125_WJC_METTL3_EV_vs_WT_F03.07262.07262.2 0.00518 14-Jun R.VLIGENEK.A "sp|P55265|DSRAD_HUMAN,tr|A0A3B3IRQ9|A0A3B3IRQ9_HUMAN,tr|A0A3B3ISU1|A0A3B3ISU1_HUMAN,tr|A0A7P0Z4K3|A0A7P0Z4K3_HUMAN,tr|A0A7P0Z4F9|A0A7P0Z4F9_HUMAN" 5 900.4916 0.89 25410 7262 2 900.491037 451.2531 Double-stranded RNA-specific adenosine deaminase OS=Homo sapiens OX=9606 GN=ADAR PE=1 SV=4 4.53 1910.6 - 6.41E+06 - - - -0.6774 - 1.446 0.347 - 94.4 1 2 0 -0.0006 8 0 0 0 2.48E+08 2.79E+08 - - - 2.716 0.9904 221125_WJC_METTL3_EV_vs_WT_F03.07264.07264.2 0.181 12-Aug R.TAEAIIR[166.11].S "sp|Q5SW79|CE170_HUMAN,sp|Q9P2G1|AKIB1_HUMAN,tr|H0Y2V6|H0Y2V6_HUMAN,tr|H0Y4T4|H0Y4T4_HUMAN" 4 782.4526 0.6 25412 7264 2 782.451821 392.2336 Centrosomal protein of 170 kDa OS=Homo sapiens OX=9606 GN=CEP170 PE=1 SV=1 5.66 1910.8 - 2.41E+06 - - - -0.9611 - 1.482 0.064 - 305 1 2 0 -0.0008 7 0 0 0 5.63E+07 9.37E+07 - - - 0.76 0.9437 221125_WJC_METTL3_EV_vs_WT_F03.07265.07265.2 2.58 12-Jul R.TAEAIIR.S "sp|Q5SW79|CE170_HUMAN,sp|Q9P2G1|AKIB1_HUMAN,tr|H0Y2V6|H0Y2V6_HUMAN,tr|H0Y4T4|H0Y4T4_HUMAN" 4 772.4443 0.56 25413 7265 2 772.445902 387.2294 Centrosomal protein of 170 kDa OS=Homo sapiens OX=9606 GN=CEP170 PE=1 SV=1 5.66 1910.8 - 1.78E+06 - - - 2.0701 - 1.211 0.053 - 195.1 1 2 0 0.0016 7 0 0 0 5.66E+07 1.02E+08 - - - 0.0386 0.9965 221125_WJC_METTL3_EV_vs_WT_F03.07282.07282.2 0.15 12-Jun K.VAQYVVR[166.11].E "sp|Q14839|CHD4_HUMAN,sp|Q8TDI0|CHD5_HUMAN,sp|Q12873|CHD3_HUMAN,tr|A0A2R8Y4X2|A0A2R8Y4X2_HUMAN,tr|A0A2U3TZM0|A0A2U3TZM0_HUMAN,tr|A0A2R8Y5M9|A0A2R8Y5M9_HUMAN,tr|A0A2R8Y685|A0A2R8Y685_HUMAN,tr|A0A2R8Y445|A0A2R8Y445_HUMAN,tr|A0A2R8YD40|A0A2R8YD40_HUMAN,tr|A0A2R8Y5J0|A0A2R8Y5J0_HUMAN,tr|A0A2R8Y425|A0A2R8Y425_HUMAN,tr|A0A2R8YFK9|A0A2R8YFK9_HUMAN,tr|A0A2R8Y8C1|A0A2R8Y8C1_HUMAN,tr|A0A0C4DGG9|A0A0C4DGG9_HUMAN,tr|A0A2R8YFD8|A0A2R8YFD8_HUMAN,tr|A0A2R8YDW2|A0A2R8YDW2_HUMAN,tr|K7ESA5|K7ESA5_HUMAN,tr|A0A2R8Y5Z7|A0A2R8Y5Z7_HUMAN,tr|A0A5F9ZHX5|A0A5F9ZHX5_HUMAN,tr|F5GWX5|F5GWX5_HUMAN,tr|K7EMY3|K7EMY3_HUMAN,tr|A0A2R8YER1|A0A2R8YER1_HUMAN,tr|K7EPV1|K7EPV1_HUMAN,tr|A0A2R8Y521|A0A2R8Y521_HUMAN,tr|A0A2R8YDJ9|A0A2R8YDJ9_HUMAN,tr|A0A2R8Y212|A0A2R8Y212_HUMAN,tr|A0A2R8YE38|A0A2R8YE38_HUMAN" 27 843.4842 0.53 25424 7282 2 843.485257 422.7494 Chromodomain-helicase-DNA-binding protein 4 OS=Homo sapiens OX=9606 GN=CHD4 PE=1 SV=2 8.72 1912.7 - 3.24E+06 - - - 1.2437 - 1.593 0.156 - 142.1 1 2 0 0.001 7 0 0 0 7.60E+07 1.42E+08 - - - 1.6682 0.9932 221125_WJC_METTL3_EV_vs_WT_F03.07284.07284.2 0.773 16-Sep R.FGEDAGYTK.R sp|Q5VVQ6|OTU1_HUMAN 1 986.4345 1.1 25426 7284 2 986.431593 494.2245 Ubiquitin thioesterase OTU1 OS=Homo sapiens OX=9606 GN=YOD1 PE=1 SV=1 4.37 1912.9 - 406680 - - - -2.9733 - 1.658 0.202 - 188.6 1 2 0 -0.0029 9 0 0 0 1.86E+07 1.69E+07 - - - 1.9948 0.8885 221125_WJC_METTL3_EV_vs_WT_F03.07287.07287.2 0.436 12-Jul K.NALNGIR[166.11].F "sp|Q6ZRY4|RBPS2_HUMAN,sp|Q93062|RBPMS_HUMAN,tr|H0YC46|H0YC46_HUMAN,tr|H0YBU9|H0YBU9_HUMAN,tr|B4E3T4|B4E3T4_HUMAN" 5 766.4325 0.04 25427 7287 2 766.429995 384.2235 RNA-binding protein with multiple splicing 2 OS=Homo sapiens OX=9606 GN=RBPMS2 PE=1 SV=1 9.75 1913.3 - 1.37E+06 - - - -3.2762 - 1.279 0.036 - 176.9 1 2 0 -0.0025 7 0 0 0 5.95E+06 1.62E+08 - - - 0.0858 0.9993 221125_WJC_METTL3_EV_vs_WT_F03.07293.07293.2 0.0288 14-Jul R.GTLDPVEK[136.11].A "sp|P11142|HSP7C_HUMAN,tr|E9PNE6|E9PNE6_HUMAN,tr|A8K7Q2|A8K7Q2_HUMAN,tr|E9PKE3|E9PKE3_HUMAN,tr|E9PN89|E9PN89_HUMAN" 5 865.4636 0.25 25431 7293 2 865.463134 433.7391 Heat shock cognate 71 kDa protein OS=Homo sapiens OX=9606 GN=HSPA8 PE=1 SV=1 4.37 1913.9 - 7.61E+07 - - - -0.5939 - 1.662 0.299 - 218.4 1 2 0 -0.0005 8 0 0 0 8.18E+09 3.26E+10 - - - 2.7814 0.986 221125_WJC_METTL3_EV_vs_WT_F03.07294.07294.2 4.41 12-Jun K.SILEQAK[136.11].R "sp|P39880|CUX1_HUMAN,sp|O14529|CUX2_HUMAN" 2 795.4582 0.94 25432 7294 2 795.457265 398.7364 Homeobox protein cut-like 1 OS=Homo sapiens OX=9606 GN=CUX1 PE=1 SV=3 5.72 1913.9 - 6.08E+06 - - - -1.1365 - 1.195 0.128 - 104.1 1 2 0 -0.0009 7 0 0 0 3.50E+08 3.73E+08 - - - 0.5506 0.9973 221125_WJC_METTL3_EV_vs_WT_F03.07295.07295.2 0.169 12-Jun R.ITGDAFK[136.11].V sp|Q96I24|FUBP3_HUMAN 1 758.4054 0.001 25433 7295 2 758.405155 380.21 Far upstream element-binding protein 3 OS=Homo sapiens OX=9606 GN=FUBP3 PE=1 SV=2 5.84 1914 - 2.71E+07 - - - -0.3296 - 1.456 0.181 - 99.8 1 2 0 -0.0003 7 0 0 0 0.00E+00 1.87E+09 - - - 1.5682 0.9983 221125_WJC_METTL3_EV_vs_WT_F03.07300.07300.2 0.0133 16-Sep K.TAGEEEMIK.L "sp|Q14331|FRG1_HUMAN,tr|E9PLY7|E9PLY7_HUMAN,tr|E9PRR7|E9PRR7_HUMAN" 3 1006.4641 1.19 25436 7300 2 1006.465636 504.2393 Protein FRG1 OS=Homo sapiens OX=9606 GN=FRG1 PE=1 SV=1 4.25 1914.6 - 699037 - - - 1.5142 - 1.327 0.345 - 207.6 1 2 0 0.0015 9 0 0 0 3.02E+07 2.54E+07 - - - 2.4072 0.9165 221125_WJC_METTL3_EV_vs_WT_F03.07308.07308.2 0.0685 12-Jul G.TLDPVEK[136.11].A "sp|P11142|HSP7C_HUMAN,tr|E9PNE6|E9PNE6_HUMAN,tr|A8K7Q2|A8K7Q2_HUMAN,tr|E9PKE3|E9PKE3_HUMAN,tr|E9PN89|E9PN89_HUMAN" 5 808.4422 0.27 25440 7308 2 808.441569 405.2284 Heat shock cognate 71 kDa protein OS=Homo sapiens OX=9606 GN=HSPA8 PE=1 SV=1 4.37 1915.6 - 1.58E+06 - - - -0.7607 - 1.336 0.289 - 189.3 1 1 0 -0.0006 7 0 0 0 7.65E+07 2.83E+08 - - - 2.0932 0.9853 221125_WJC_METTL3_EV_vs_WT_F03.07313.07313.2 0.428 16-Aug R.LPPPADYNK[136.11].E "sp|P51116|FXR2_HUMAN,tr|I3L1Z2|I3L1Z2_HUMAN" 2 1021.5324 1.73 25442 7313 2 1021.535261 511.7735 Fragile X mental retardation syndrome-related protein 2 OS=Homo sapiens OX=9606 GN=FXR2 PE=1 SV=2 5.83 1916.2 - 592050 - - - 2.8046 - 1.385 0.181 - 216.4 1 2 0 0.0029 9 0 0 0 3.13E+07 1.81E+07 - - - 1.3192 0.9462 221125_WJC_METTL3_EV_vs_WT_F03.07316.07316.2 0.133 16-Jun K.TC[160.03]GEGSR[166.11]YR.K "sp|Q9P2N4|ATS9_HUMAN,tr|H0Y859|H0Y859_HUMAN" 2 1094.4803 - 25444 7316 2 1094.480972 548.2474 A disintegrin and metalloproteinase with thrombospondin motifs 9 OS=Homo sapiens OX=9606 GN=ADAMTS9 PE=1 SV=4 7.89 1916.6 - 463061 - - - 0.6496 - 1.253 0.203 - 145.8 1 2 1 0.0007 9 0 0 0 - - - - - 1.1926 0.9935 221125_WJC_METTL3_EV_vs_WT_F03.07322.07322.2 0.000178 18-Aug R.IYGETPEAC[160.03]R.Q sp|P51116|FXR2_HUMAN 1 1194.5339 0.95 25448 7322 2 1194.534678 598.2742 Fragile X mental retardation syndrome-related protein 2 OS=Homo sapiens OX=9606 GN=FXR2 PE=1 SV=2 4.53 1917.3 - 579974 - - - 0.632 - 1.573 0.095 - 134.6 1 2 0 0.0008 10 0 0 0 6.17E+07 6.47E+07 - - - 1.0069 0.9928 221125_WJC_METTL3_EV_vs_WT_F03.07331.07331.2 2.7 12-Jul K.SILEQAK.R "sp|P39880|CUX1_HUMAN,sp|O14529|CUX2_HUMAN" 2 787.444 0.64 25450 7331 2 787.444018 394.7293 Homeobox protein cut-like 1 OS=Homo sapiens OX=9606 GN=CUX1 PE=1 SV=3 5.72 1918.6 - 7.06E+06 - - - 0.0622 - 1.16 0.181 - 144.9 1 2 0 0 7 0 0 0 3.65E+08 5.69E+08 - - - 0.8481 0.9892 221125_WJC_METTL3_EV_vs_WT_F03.07333.07333.2 0.2 14-Aug K.LQNDFAEK[136.11].E "sp|Q13948|CASP_HUMAN,sp|P39880|CUX1_HUMAN,tr|A0A2R8Y8D0|A0A2R8Y8D0_HUMAN,tr|A0A2R8Y852|A0A2R8Y852_HUMAN,tr|A0A2R8YDI1|A0A2R8YDI1_HUMAN" 5 971.4804 1.42 25451 7333 2 971.476638 486.7475 Protein CASP OS=Homo sapiens OX=9606 GN=CUX1 PE=1 SV=2 4.37 1918.8 - 1.57E+06 - - - -3.8323 - 1.513 0.249 - 192.3 1 2 0 -0.0037 8 0 0 0 1.35E+08 9.54E+07 - - - 2.1278 0.9986 221125_WJC_METTL3_EV_vs_WT_F03.07335.07335.2 0.0738 20-Sep R.LSGAGGAGGFR.S sp|Q16352|AINX_HUMAN 1 948.4777 1.2 25452 7335 2 948.475979 475.2461 Alpha-internexin OS=Homo sapiens OX=9606 GN=INA PE=1 SV=2 9.75 1919 - 4.34E+06 - - - -1.844 - 1.815 0.276 - 190.6 1 2 0 -0.0018 11 0 0 0 1.93E+08 1.61E+08 - - - 2.6915 0.9998 221125_WJC_METTL3_EV_vs_WT_F03.07337.07337.2 0.00012 14-Jul K.LGNSC[160.03]EFR.L "sp|P55265|DSRAD_HUMAN,tr|A0A3B3ITG9|A0A3B3ITG9_HUMAN,tr|A0A3B3IRQ9|A0A3B3IRQ9_HUMAN,tr|A0A3B3ISU1|A0A3B3ISU1_HUMAN,tr|A0A7P0Z4K3|A0A7P0Z4K3_HUMAN,tr|A0A3B3ISX1|A0A3B3ISX1_HUMAN,tr|A0A7P0Z4F9|A0A7P0Z4F9_HUMAN" 7 981.4338 0.74 25453 7337 2 981.432613 491.7242 Double-stranded RNA-specific adenosine deaminase OS=Homo sapiens OX=9606 GN=ADAR PE=1 SV=4 5.99 1919.2 - 1.49E+06 - - - -1.2247 - 1.593 0.533 - 144.4 1 2 0 -0.0012 8 0 0 0 9.91E+07 1.33E+08 - - - 4.3816 0.9994 221125_WJC_METTL3_EV_vs_WT_F03.07338.07338.2 0.00127 18-Sep R.VIVGGSSEYK.L "sp|Q14683|SMC1A_HUMAN,tr|G8JLG1|G8JLG1_HUMAN,tr|A0A6Q8PHC3|A0A6Q8PHC3_HUMAN" 3 1037.5393 0.96 25454 7338 2 1037.537798 519.7769 Structural maintenance of chromosomes protein 1A OS=Homo sapiens OX=9606 GN=SMC1A PE=1 SV=2 5.97 1919.4 - 664041 - - - -1.4727 - 1.443 0.432 - 229.4 1 2 0 -0.0015 10 0 0 0 2.55E+08 2.66E+08 - - - 3.2549 0.9995 221125_WJC_METTL3_EV_vs_WT_F03.07343.07343.2 0.00156 18-Sep R.VIVGGSSEYK[136.11].L "sp|Q14683|SMC1A_HUMAN,tr|G8JLG1|G8JLG1_HUMAN,tr|A0A6Q8PHC3|A0A6Q8PHC3_HUMAN" 3 1045.5535 0.96 25457 7343 2 1045.552951 523.784 Structural maintenance of chromosomes protein 1A OS=Homo sapiens OX=9606 GN=SMC1A PE=1 SV=2 5.97 1919.8 - 1.03E+06 - - - -0.5499 - 1.674 0.347 - 229 1 2 0 -0.0006 10 0 0 0 2.55E+08 2.66E+08 - - - 3.0419 0.9811 221125_WJC_METTL3_EV_vs_WT_F03.07347.07347.2 0.0194 14/20 M.AAAAAAAAVVR[166.11].G "sp|O43347|MSI1H_HUMAN,tr|H0YHB7|H0YHB7_HUMAN" 2 950.5537 1.52 25460 7347 2 950.551498 476.2841 RNA-binding protein Musashi homolog 1 OS=Homo sapiens OX=9606 GN=MSI1 PE=1 SV=1 9.79 1920.2 - 4.84E+06 - - - -2.2997 - 3.14 0.37 - 983.7 1 1 0 -0.0022 11 0 0 0 2.29E+08 1.51E+08 - - - 4.8685 0.9949 221125_WJC_METTL3_EV_vs_WT_F03.07349.07349.2 0.105 12-Jul K.LVSIDSK[136.11].A "sp|O75369|FLNB_HUMAN,sp|Q14315|FLNC_HUMAN,sp|P21333|FLNA_HUMAN,tr|A0A7P0NMY4|A0A7P0NMY4_HUMAN,tr|Q60FE5|Q60FE5_HUMAN,tr|A0A7I2V3E6|A0A7I2V3E6_HUMAN,tr|A0A804HK76|A0A804HK76_HUMAN,tr|A0A804HJC2|A0A804HJC2_HUMAN,tr|A0A087WWY3|A0A087WWY3_HUMAN,tr|A0A804HL72|A0A804HL72_HUMAN,tr|F8WE98|F8WE98_HUMAN" 11 768.4473 3.03 25462 7349 2 768.44574 385.2309 Filamin-B OS=Homo sapiens OX=9606 GN=FLNB PE=1 SV=2 5.84 1920.3 - 3.78E+06 - - - -1.991 - 1.409 0.206 - 171.9 1 2 0 -0.0015 7 0 0 0 3.84E+08 1.27E+08 - - - 1.6485 0.927 221125_WJC_METTL3_EV_vs_WT_F03.07358.07358.2 0.0125 18-Aug K.ELHNTPYGTA.S sp|Q9NXV2|KCTD5_HUMAN 1 1101.5091 - 25464 7358 2 1101.508036 551.7618 BTB\POZ domain-containing protein KCTD5 OS=Homo sapiens OX=9606 GN=KCTD5 PE=1 SV=1 5.24 1921.6 - 815224 - - - -0.9551 - 1.32 0.333 - 200.3 1 1 0 -0.0011 10 0 0 0 - - - - - 2.2752 0.9999 221125_WJC_METTL3_EV_vs_WT_F03.07363.07363.2 5.89E-06 18-Sep R.IYGETPEAC[160.03]R[166.11].Q sp|P51116|FXR2_HUMAN 1 1204.5422 1.27 25466 7363 2 1204.540867 603.2784 Fragile X mental retardation syndrome-related protein 2 OS=Homo sapiens OX=9606 GN=FXR2 PE=1 SV=2 4.53 1922.2 - 1.57E+06 - - - -1.1008 - 1.919 0.613 - 271.3 1 2 0 -0.0013 10 0 0 0 6.02E+07 4.72E+07 - - - 5.3876 0.9993 221125_WJC_METTL3_EV_vs_WT_F03.07364.07364.2 0.0501 18-Sep K.ILAHNGLVGR[166.11].L "sp|Q9Y6M1|IF2B2_HUMAN,tr|F8W930|F8W930_HUMAN" 2 1058.6224 1.93 25467 7364 2 1058.62384 530.3185 Insulin-like growth factor 2 mRNA-binding protein 2 OS=Homo sapiens OX=9606 GN=IGF2BP2 PE=1 SV=2 9.76 1922.3 - 557379 - - - 1.33 - 1.654 0.362 - 309 1 2 0 0.0014 10 0 0 0 3.72E+07 1.93E+07 - - - 3.1189 0.9189 221125_WJC_METTL3_EV_vs_WT_F03.07369.07369.2 2.61 12-Jun R.VYYVSEK.L "sp|Q9Y221|NIP7_HUMAN,tr|J3QLW7|J3QLW7_HUMAN" 2 886.4436 0.18 25469 7369 2 886.441541 444.2291 60S ribosome subunit biogenesis protein NIP7 homolog OS=Homo sapiens OX=9606 GN=NIP7 PE=1 SV=1 5.97 1923 - 2.31E+06 - - - -2.3611 - 1.065 0.087 - 157.4 1 2 0 -0.0021 7 0 0 0 1.19E+08 6.46E+08 - - - -0.1175 0.9996 221125_WJC_METTL3_EV_vs_WT_F03.07374.07374.2 0.00718 16-Sep K.ILSSDDYGK.D "sp|Q01082|SPTB2_HUMAN,tr|A0A087WUZ3|A0A087WUZ3_HUMAN,tr|F8W6C1|F8W6C1_HUMAN" 3 996.4764 1.81 25472 7374 2 996.476449 499.2455 "Spectrin beta chain, non-erythrocytic 1 OS=Homo sapiens OX=9606 GN=SPTBN1 PE=1 SV=2" 4.21 1923.6 - 1.14E+06 - - - 0.0582 - 1.519 0.392 - 153.7 1 2 0 0.0001 9 0 0 0 5.64E+07 3.12E+07 - - - 3.1457 0.9857 221125_WJC_METTL3_EV_vs_WT_F03.07378.07378.2 3.88 12-Jun K.IIAPPER.K "sp|P63261|ACTG_HUMAN,sp|P68133|ACTS_HUMAN,sp|P62736|ACTA_HUMAN,sp|P68032|ACTC_HUMAN,sp|Q562R1|ACTBL_HUMAN,sp|P60709|ACTB_HUMAN,sp|P63267|ACTH_HUMAN,tr|A0A2R8YFE2|A0A2R8YFE2_HUMAN,tr|A0A804GS07|A0A804GS07_HUMAN,tr|A0A6Q8PFE4|A0A6Q8PFE4_HUMAN,tr|A0A804HKV3|A0A804HKV3_HUMAN,tr|I3L4N8|I3L4N8_HUMAN" 12 794.465 0.86 25474 7378 2 794.463855 398.2398 "Actin, cytoplasmic 2 OS=Homo sapiens OX=9606 GN=ACTG1 PE=1 SV=1" 6 1924 - 5.73E+06 - - - -1.4891 - 1.362 0.106 - 136.4 2 2 0 -0.0012 7 0 0 0 2.86E+08 3.35E+08 - - - 0.668 0.9824 221125_WJC_METTL3_EV_vs_WT_F03.07379.07379.2 0.408 12-May R.VSIYDSK.R "sp|P55265|DSRAD_HUMAN,tr|A0A3B3IRQ9|A0A3B3IRQ9_HUMAN,tr|A0A7P0Z4K3|A0A7P0Z4K3_HUMAN,tr|A0A7P0Z4F9|A0A7P0Z4F9_HUMAN" 4 810.4123 0.46 25475 7379 2 810.411582 406.2134 Double-stranded RNA-specific adenosine deaminase OS=Homo sapiens OX=9606 GN=ADAR PE=1 SV=4 5.81 1924.1 - 4.94E+06 - - - -0.9279 - 0.97 0.189 - 63.3 1 2 0 -0.0008 7 0 0 0 1.59E+08 3.42E+08 - - - 0.3402 0.9971 221125_WJC_METTL3_EV_vs_WT_F03.07380.07380.2 0.459 12-Jun R.FSGVPDR.F "sp|A0A075B6R9|KVD24_HUMAN,sp|A0A0C4DH68|KV224_HUMAN,sp|A2NJV5|KV229_HUMAN,sp|A0A075B6S2|KVD29_HUMAN,sp|A0A0A0MRZ7|KVD26_HUMAN" 5 776.3817 7449.32 25476 7380 2 776.38012 389.1981 Probable non-functional immunoglobulin kappa variable 2D-24 OS=Homo sapiens OX=9606 GN=IGKV2D-24 PE=1 SV=1 5.84 1924.1 - 3.21E+06 - - - -2.0389 - 1.392 0.279 - 108.4 1 2 0 -0.0016 7 0 0 0 9.73E+11 1.31E+08 - - - 2.1492 0.9918 221125_WJC_METTL3_EV_vs_WT_F03.07399.07399.2 0.108 14-Aug R.NILASNPR.V "sp|Q9Y294|ASF1A_HUMAN,sp|Q9NVP2|ASF1B_HUMAN,tr|K7ES22|K7ES22_HUMAN" 3 883.4876 1.33 25484 7399 2 883.489783 442.7511 Histone chaperone ASF1A OS=Homo sapiens OX=9606 GN=ASF1A PE=1 SV=1 9.75 1926.5 - 4.20E+06 - - - 2.5105 - 1.327 0.232 - 240.8 1 2 0 0.0022 8 0 0 0 1.06E+09 7.92E+08 - - - 1.6071 0.9969 221125_WJC_METTL3_EV_vs_WT_F03.07405.07405.2 0.0615 16-Oct K.AGPVAVQVK[136.11].A "sp|Q13428|TCOF_HUMAN,tr|E7ETY2|E7ETY2_HUMAN,tr|H0Y8Y7|H0Y8Y7_HUMAN,tr|A0A3B3IS06|A0A3B3IS06_HUMAN,tr|A0A6I8PRA0|A0A6I8PRA0_HUMAN" 5 875.532 0.79 25488 7405 2 875.530165 438.7733 Treacle protein OS=Homo sapiens OX=9606 GN=TCOF1 PE=1 SV=3 8.8 1927.3 - 3.81E+06 - - - -2.0982 - 1.603 0.23 - 376.2 1 2 0 -0.0018 9 0 0 0 1.32E+08 1.67E+08 - - - 2.1044 0.9958 221125_WJC_METTL3_EV_vs_WT_F03.07407.07407.2 1.15 12-Aug K.LVQIASR.T "sp|Q1KMD3|HNRL2_HUMAN,tr|H3BQZ7|H3BQZ7_HUMAN" 2 785.4759 1.89 25490 7407 2 785.474283 393.7452 Heterogeneous nuclear ribonucleoprotein U-like protein 2 OS=Homo sapiens OX=9606 GN=HNRNPUL2 PE=1 SV=1 9.75 1927.4 - 4.39E+06 - - - -2.107 - 1.768 0.138 - 259.2 1 2 0 -0.0017 7 0 0 0 2.39E+08 1.26E+08 - - - 1.8653 0.8838 221125_WJC_METTL3_EV_vs_WT_F03.07408.07408.2 0.362 12-Jun R.VEYFVDK[136.11].Q "sp|A6NED2|RCCD1_HUMAN,tr|G3V2I3|G3V2I3_HUMAN" 2 906.4578 0.02 25491 7408 2 906.454051 454.2362 RCC1 domain-containing protein 1 OS=Homo sapiens OX=9606 GN=RCCD1 PE=1 SV=1 4.37 1927.4 - 2.24E+06 - - - -4.1734 - 1.071 0.166 - 122.7 1 2 0 -0.0038 7 0 0 0 1.77E+06 9.04E+07 - - - 0.4832 0.936 221125_WJC_METTL3_EV_vs_WT_F03.07419.07419.2 3.12 12-Jun K.LEAVQYK.T "sp|P01040|CYTA_HUMAN,tr|C9J0E4|C9J0E4_HUMAN" 2 849.4596 86.69 25495 7419 2 849.457576 425.7371 Cystatin-A OS=Homo sapiens OX=9606 GN=CSTA PE=1 SV=1 6 1928.8 - 3.71E+06 - - - -2.4051 - 1.35 0.028 - 95.7 2 2 0 -0.002 7 0 0 0 7.96E+08 9.18E+06 - - - 0.0636 0.9853 221125_WJC_METTL3_EV_vs_WT_F03.07423.07423.2 0.104 14-Jun K.VIEPGC[160.03]VR.V sp|O60884|DNJA2_HUMAN 1 928.48 0.23 25496 7423 2 928.477595 465.2473 DnaJ homolog subfamily A member 2 OS=Homo sapiens OX=9606 GN=DNAJA2 PE=1 SV=1 5.97 1929.4 - 3.98E+06 - - - -2.6301 - 1.413 0.214 - 103.7 11 2 0 -0.0024 8 0 0 0 9.49E+07 4.14E+08 - - - 1.1983 0.9637 221125_WJC_METTL3_EV_vs_WT_F03.07427.07427.2 0.0476 14-Jul R.VSPEEAIK.C "sp|P05198|IF2A_HUMAN,tr|H0YJS4|H0YJS4_HUMAN,tr|G3V4T5|G3V4T5_HUMAN" 3 871.4651 1.48 25498 7427 2 871.459974 436.7398 Eukaryotic translation initiation factor 2 subunit 1 OS=Homo sapiens OX=9606 GN=EIF2S1 PE=1 SV=3 4.53 1929.9 - 4.24E+06 - - - -5.8798 - 1.416 0.303 - 152.5 1 2 0 -0.0051 8 0 0 0 3.11E+09 2.10E+09 - - - 2.3264 0.9926 221125_WJC_METTL3_EV_vs_WT_F03.07482.07482.2 1.01 12-Jul R.QQLLADR.Q "sp|Q8TAQ2|SMRC2_HUMAN,tr|F8VXC8|F8VXC8_HUMAN" 2 842.461 1.68 25509 7482 2 842.459204 422.2378 SWI\SNF complex subunit SMARCC2 OS=Homo sapiens OX=9606 GN=SMARCC2 PE=1 SV=1 5.84 1938.2 - 4.72E+06 - - - -2.1508 - 1.427 0.175 - 236.7 1 2 0 -0.0018 7 0 0 0 1.70E+08 1.02E+08 - - - 1.4596 0.9846 221125_WJC_METTL3_EV_vs_WT_F03.07485.07485.2 0.00197 14-Sep R.TAQTILEK[136.11].E sp|O75792|RNH2A_HUMAN 1 910.5215 1.94 25510 7485 2 910.515938 456.268 Ribonuclease H2 subunit A OS=Homo sapiens OX=9606 GN=RNASEH2A PE=1 SV=2 5.66 1938.6 - 2.10E+06 - - - -6.1053 - 1.826 0.335 - 290.6 1 2 0 -0.0056 8 0 0 0 2.59E+08 1.34E+08 - - - 3.3296 0.9998 221125_WJC_METTL3_EV_vs_WT_F03.07490.07490.2 4.78E-05 18-Nov R.IYGESADAVK.K "sp|P51114|FXR1_HUMAN,tr|E7EU85|E7EU85_HUMAN,tr|E9PFF5|E9PFF5_HUMAN,tr|B4DXZ6|B4DXZ6_HUMAN" 4 1051.5186 1.8 25513 7490 2 1051.516948 526.7666 Fragile X mental retardation syndrome-related protein 1 OS=Homo sapiens OX=9606 GN=FXR1 PE=1 SV=3 4.37 1939.2 - 4.12E+06 - - - -1.5616 - 1.98 0.54 - 291.2 1 2 0 -0.0016 10 0 0 0 2.07E+08 1.15E+08 - - - 4.9357 0.9961 221125_WJC_METTL3_EV_vs_WT_F03.07499.07499.2 0.31 14-Aug K.GANPVEIR.R "sp|P10809|CH60_HUMAN,tr|A0A7I2V2X6|A0A7I2V2X6_HUMAN,tr|A0A7I2YQK6|A0A7I2YQK6_HUMAN,tr|A0A7I2V599|A0A7I2V599_HUMAN,tr|E7EXB4|E7EXB4_HUMAN,tr|A0A7I2YQ71|A0A7I2YQ71_HUMAN,tr|E7ESH4|E7ESH4_HUMAN,tr|A0A7I2V5M1|A0A7I2V5M1_HUMAN,tr|A0A7I2V5K3|A0A7I2V5K3_HUMAN,tr|A0A7I2V369|A0A7I2V369_HUMAN" 10 854.461 1.29 25517 7499 2 854.458616 428.2378 "60 kDa heat shock protein, mitochondrial OS=Homo sapiens OX=9606 GN=HSPD1 PE=1 SV=2" 6 1940.3 - 7.62E+06 - - - -2.8088 - 1.63 0.252 - 336 1 2 0 -0.0024 8 0 0 0 3.73E+10 2.89E+10 - - - 2.3751 0.9977 221125_WJC_METTL3_EV_vs_WT_F03.07505.07505.2 0.00648 14-Aug K.GANPVEIR[166.11].R "sp|P10809|CH60_HUMAN,tr|A0A7I2V2X6|A0A7I2V2X6_HUMAN,tr|A0A7I2YQK6|A0A7I2YQK6_HUMAN,tr|A0A7I2V599|A0A7I2V599_HUMAN,tr|E7EXB4|E7EXB4_HUMAN,tr|A0A7I2YQ71|A0A7I2YQ71_HUMAN,tr|E7ESH4|E7ESH4_HUMAN,tr|A0A7I2V5M1|A0A7I2V5M1_HUMAN,tr|A0A7I2V5K3|A0A7I2V5K3_HUMAN,tr|A0A7I2V369|A0A7I2V369_HUMAN" 10 864.4693 1.29 25521 7505 2 864.466127 433.2419 "60 kDa heat shock protein, mitochondrial OS=Homo sapiens OX=9606 GN=HSPD1 PE=1 SV=2" 6 1940.9 - 8.32E+06 - - - -3.6543 - 1.828 0.36 - 346.4 1 2 0 -0.0032 8 0 0 0 3.73E+10 2.89E+10 - - - 3.5183 0.998 221125_WJC_METTL3_EV_vs_WT_F03.07511.07511.2 8.81E-05 18-Nov R.IYGESADAVK[136.11].K "sp|P51114|FXR1_HUMAN,tr|E7EU85|E7EU85_HUMAN,tr|E9PFF5|E9PFF5_HUMAN,tr|B4DXZ6|B4DXZ6_HUMAN" 4 1059.5328 1.8 25524 7511 2 1059.527783 530.7737 Fragile X mental retardation syndrome-related protein 1 OS=Homo sapiens OX=9606 GN=FXR1 PE=1 SV=3 4.37 1941.6 - 3.15E+06 - - - -4.7257 - 1.978 0.513 - 304 1 2 0 -0.005 10 0 0 0 2.07E+08 1.15E+08 - - - 4.7324 0.9996 221125_WJC_METTL3_EV_vs_WT_F03.07515.07515.2 6.73E-05 16-Oct K.NMMAAC[160.03]DPR[166.11].H "sp|P04350|TBB4A_HUMAN,sp|Q9BVA1|TBB2B_HUMAN,sp|A6NNZ2|TBB8B_HUMAN,sp|P07437|TBB5_HUMAN,sp|Q13509|TBB3_HUMAN,sp|Q13885|TBB2A_HUMAN,sp|P68371|TBB4B_HUMAN,sp|Q9BUF5|TBB6_HUMAN,sp|Q3ZCM7|TBB8_HUMAN,tr|A0A0B4J269|A0A0B4J269_HUMAN,tr|Q5ST81|Q5ST81_HUMAN,tr|Q5JP53|Q5JP53_HUMAN,tr|K7ESM5|K7ESM5_HUMAN,tr|A0A075B736|A0A075B736_HUMAN,tr|Q5SQY0|Q5SQY0_HUMAN" 15 1074.4284 0.46 25526 7515 2 1074.425601 538.2215 Tubulin beta-4A chain OS=Homo sapiens OX=9606 GN=TUBB4A PE=1 SV=2 5.83 1942.1 - 2.08E+06 - - - -2.6293 - 1.693 0.574 - 291 1 2 0 -0.0028 9 0 0 0 4.53E+07 9.82E+07 - - - 4.8029 0.9997 221125_WJC_METTL3_EV_vs_WT_F03.07524.07524.2 0.000737 16-Dec K.MEADPELSK.F "sp|O75643|U520_HUMAN,tr|A0A494C1A5|A0A494C1A5_HUMAN" 2 1018.4641 2.55 25530 7524 2 1018.462125 510.2393 U5 small nuclear ribonucleoprotein 200 kDa helicase OS=Homo sapiens OX=9606 GN=SNRNP200 PE=1 SV=2 4.14 1943.2 - 2.79E+06 - - - -1.951 - 1.932 0.499 - 539.3 1 2 0 -0.002 9 0 0 0 1.82E+08 7.15E+07 - - - 4.6312 0.9756 221125_WJC_METTL3_EV_vs_WT_F03.07528.07528.2 0.018 16-Oct R.ILQEGVDPK.K "sp|P40939|ECHA_HUMAN,tr|H0YFD6|H0YFD6_HUMAN,tr|A0A2R8Y4F5|A0A2R8Y4F5_HUMAN" 3 997.5444 0.95 25532 7528 2 997.539307 499.7795 "Trifunctional enzyme subunit alpha, mitochondrial OS=Homo sapiens OX=9606 GN=HADHA PE=1 SV=2" 4.37 1943.6 - 1.86E+06 - - - -5.1166 - 1.576 0.252 - 277.7 1 2 0 -0.0051 9 0 0 0 1.71E+08 1.80E+08 - - - 2.2167 0.9978 221125_WJC_METTL3_EV_vs_WT_F03.07530.07530.2 0.000609 14-Jul R.LTEGC[160.03]SFR.R "sp|Q71UM5|RS27L_HUMAN,sp|P42677|RS27_HUMAN,tr|H0YMV8|H0YMV8_HUMAN,tr|C9J1C5|C9J1C5_HUMAN" 4 968.4386 0.49 25533 7530 2 968.434845 485.2266 40S ribosomal protein S27-like OS=Homo sapiens OX=9606 GN=RPS27L PE=1 SV=3 5.99 1943.8 - 1.69E+07 - - - -3.8423 - 1.594 0.444 - 143.8 1 2 0 -0.0037 8 0 0 0 1.49E+09 3.03E+09 - - - 3.7254 0.9886 221125_WJC_METTL3_EV_vs_WT_F03.07535.07535.2 0.383 14-Aug K.TLLVNNNR.L "sp|P09661|RU2A_HUMAN,tr|H0YKK0|H0YKK0_HUMAN" 2 942.5247 1.4 25535 7535 2 942.521231 472.2696 U2 small nuclear ribonucleoprotein A' OS=Homo sapiens OX=9606 GN=SNRPA1 PE=1 SV=2 9.41 1944.4 - 2.64E+06 - - - -3.6583 - 1.544 0.22 - 220.6 1 2 0 -0.0034 8 0 0 0 1.58E+08 1.12E+08 - - - 1.9749 0.7904 221125_WJC_METTL3_EV_vs_WT_F03.07541.07541.2 0.0138 14-Jul K.TADEVPLK[136.11].L sp|Q9NZI8|IF2B1_HUMAN 1 879.4793 1.47 25538 7541 2 880.485447 440.7469 Insulin-like growth factor 2 mRNA-binding protein 1 OS=Homo sapiens OX=9606 GN=IGF2BP1 PE=1 SV=2 4.37 1945.1 - 3.78E+07 - - - 1144.0281 - 1.353 0.345 - 225 1 2 0 1.0061 8 0 0 0 3.13E+09 2.13E+09 - - - 2.185 0.994 221125_WJC_METTL3_EV_vs_WT_F03.07543.07543.2 0.482 12-Jun K.LTNEDFR.K "sp|Q13123|RED_HUMAN,tr|D6RAY9|D6RAY9_HUMAN,tr|D6REL4|D6REL4_HUMAN,tr|E7EQZ7|E7EQZ7_HUMAN,tr|D6RCQ4|D6RCQ4_HUMAN" 5 893.4243 0.78 25539 7543 2 893.423133 447.7194 Protein Red OS=Homo sapiens OX=9606 GN=IK PE=1 SV=3 4.37 1945.3 - 3.27E+06 - - - -1.3017 - 1.362 0.161 - 122.4 1 2 0 -0.0012 7 0 0 0 2.56E+08 3.28E+08 - - - 1.2087 0.9998 221125_WJC_METTL3_EV_vs_WT_F03.07549.07549.2 0.000335 16-Oct K.NMMAAC[160.03]DPR.H "sp|P04350|TBB4A_HUMAN,sp|Q9BVA1|TBB2B_HUMAN,sp|A6NNZ2|TBB8B_HUMAN,sp|P07437|TBB5_HUMAN,sp|Q13509|TBB3_HUMAN,sp|Q13885|TBB2A_HUMAN,sp|P68371|TBB4B_HUMAN,sp|Q9BUF5|TBB6_HUMAN,sp|Q3ZCM7|TBB8_HUMAN,tr|A0A0B4J269|A0A0B4J269_HUMAN,tr|Q5ST81|Q5ST81_HUMAN,tr|Q5JP53|Q5JP53_HUMAN,tr|K7ESM5|K7ESM5_HUMAN,tr|A0A075B736|A0A075B736_HUMAN,tr|Q5SQY0|Q5SQY0_HUMAN" 15 1064.4202 0.46 25541 7549 2 1064.419352 533.2174 Tubulin beta-4A chain OS=Homo sapiens OX=9606 GN=TUBB4A PE=1 SV=2 5.83 1946.1 - 1.07E+06 - - - -0.7553 - 1.695 0.526 - 319.1 1 2 0 -0.0008 9 0 0 0 4.53E+07 9.82E+07 - - - 4.4524 0.994 221125_WJC_METTL3_EV_vs_WT_F03.07554.07554.2 0.0234 14-Aug R.LLEK[136.11]PYVR[166.11].D "sp|Q9Y520|PRC2C_HUMAN,tr|E7EPN9|E7EPN9_HUMAN" 2 1034.6243 0.77 25544 7554 2 1034.620708 518.3194 Protein PRRC2C OS=Homo sapiens OX=9606 GN=PRRC2C PE=1 SV=4 8.59 1946.7 - 1.55E+06 - - - -3.5066 - 1.507 0.293 - 255.7 1 2 0 -0.0036 8 0 0 0 5.86E+07 7.64E+07 - - - 2.4409 0.9995 221125_WJC_METTL3_EV_vs_WT_F03.07561.07561.2 0.0286 14-Aug R.LTEGC[160.03]SFR[166.11].R "sp|Q71UM5|RS27L_HUMAN,sp|P42677|RS27_HUMAN,tr|H0YMV8|H0YMV8_HUMAN,tr|C9J1C5|C9J1C5_HUMAN" 4 978.4468 0.49 25548 7561 2 978.444589 490.2307 40S ribosomal protein S27-like OS=Homo sapiens OX=9606 GN=RPS27L PE=1 SV=3 5.99 1947.5 - 7.64E+07 - - - -2.2965 - 1.849 0.452 - 252.2 1 2 0 -0.0022 8 0 0 0 1.49E+09 3.03E+09 - - - 4.2325 0.999 221125_WJC_METTL3_EV_vs_WT_F03.07569.07569.2 0.0357 16-Sep R.TALAMGADR[166.11].G sp|P38117|ETFB_HUMAN 1 914.4519 1.77 25552 7569 2 914.449633 458.2332 Electron transfer flavoprotein subunit beta OS=Homo sapiens OX=9606 GN=ETFB PE=1 SV=3 5.5 1948.3 - 5.68E+06 - - - -2.502 - 1.96 0.342 - 338.8 1 2 0 -0.0023 9 0 0 0 3.62E+08 2.05E+08 - - - 3.5132 0.8956 221125_WJC_METTL3_EV_vs_WT_F03.07570.07570.2 3.53 14-Jun K.ETAESVLK[136.11].K "sp|P34932|HSP74_HUMAN,tr|A0A087WTS8|A0A087WTS8_HUMAN,tr|A0A087WYC1|A0A087WYC1_HUMAN" 3 883.4742 0.17 25553 7570 2 883.471688 442.7444 Heat shock 70 kDa protein 4 OS=Homo sapiens OX=9606 GN=HSPA4 PE=1 SV=4 4.53 1948.4 - 7.93E+06 - - - -2.858 - 1.165 0.059 - 186.2 1 2 0 -0.0025 8 0 0 0 3.01E+07 1.72E+08 - - - -0.0634 0.9991 221125_WJC_METTL3_EV_vs_WT_F03.07578.07578.2 0.000209 14-Oct R.LNNDPGWK[136.11].N sp|Q9H0D6|XRN2_HUMAN 1 950.4701 1.24 25557 7578 2 950.467157 476.2423 5'-3' exoribonuclease 2 OS=Homo sapiens OX=9606 GN=XRN2 PE=1 SV=1 5.84 1949.2 - 3.52E+06 - - - -3.1279 - 1.662 0.501 - 289.8 1 2 0 -0.003 8 0 0 0 1.54E+08 1.24E+08 - - - 4.2726 0.999 221125_WJC_METTL3_EV_vs_WT_F03.07582.07582.2 0.00299 16-Jul R.TALAMGADR.G sp|P38117|ETFB_HUMAN 1 904.4437 1.75 25559 7582 2 904.440941 453.2291 Electron transfer flavoprotein subunit beta OS=Homo sapiens OX=9606 GN=ETFB PE=1 SV=3 5.5 1949.7 - 9.94E+06 - - - -2.9963 - 1.796 0.431 - 168.9 1 2 0 -0.0027 9 0 0 0 3.55E+08 2.03E+08 - - - 3.9176 0.9995 221125_WJC_METTL3_EV_vs_WT_F03.07583.07583.2 0.00267 16-Jul K.C[160.03]VGLSPDGR.L "sp|Q15269|PWP2_HUMAN,tr|A0A0B4J2E5|A0A0B4J2E5_HUMAN,tr|C9J544|C9J544_HUMAN" 3 959.4495 84.59 25560 7583 2 959.449196 480.732 Periodic tryptophan protein 2 homolog OS=Homo sapiens OX=9606 GN=PWP2 PE=2 SV=2 5.83 1949.9 - 691921 - - - -0.2804 - 1.554 0.38 - 133.3 1 2 0 -0.0003 9 0 0 0 1.57E+07 1.85E+05 - - - 3.1229 0.9921 221125_WJC_METTL3_EV_vs_WT_F03.07584.07584.2 0.241 16-Jul R.ILQEGVDPK[136.11].K "sp|P40939|ECHA_HUMAN,tr|H0YFD6|H0YFD6_HUMAN,tr|A0A2R8Y4F5|A0A2R8Y4F5_HUMAN" 3 1005.5586 0.95 25561 7584 2 1005.556316 503.7866 "Trifunctional enzyme subunit alpha, mitochondrial OS=Homo sapiens OX=9606 GN=HADHA PE=1 SV=2" 4.37 1949.9 - 3.49E+06 - - - -2.2823 - 1.25 0.242 - 154.5 1 2 0 -0.0023 9 0 0 0 1.71E+08 1.80E+08 - - - 1.4733 0.9997 221125_WJC_METTL3_EV_vs_WT_F03.07585.07585.2 0.00925 18-Oct K.AEAESLYQSK.Y sp|P04264|K2C1_HUMAN 1 1124.535 999 25562 7585 2 1124.534058 563.2748 "Keratin, type II cytoskeletal 1 OS=Homo sapiens OX=9606 GN=KRT1 PE=1 SV=6" 4.53 1950 - 600110 - - - -0.8101 - 1.709 0.411 - 361.1 1 2 0 -0.0009 10 0 0 0 1.56E+07 0.00E+00 - - - 3.5722 0.994 221125_WJC_METTL3_EV_vs_WT_F03.07588.07588.2 0.461 12-Jun R.IGVITNR.E sp|P62701|RS4X_HUMAN 1 771.4603 0.98 25563 7588 2 771.459774 386.7374 "40S ribosomal protein S4, X isoform OS=Homo sapiens OX=9606 GN=RPS4X PE=1 SV=2" 9.75 1950.4 - 2.29E+07 - - - -0.665 - 1.351 0.138 - 148.6 1 2 0 -0.0005 7 0 0 0 1.73E+09 1.77E+09 - - - 1.0134 0.9972 221125_WJC_METTL3_EV_vs_WT_F03.07590.07590.2 0.165 16-Aug R.LLQQNTQLK[136.11].R "sp|Q01664|TFAP4_HUMAN,tr|I3L254|I3L254_HUMAN" 2 1092.6383 1.62 25564 7590 2 1092.637013 547.3264 Transcription factor AP-4 OS=Homo sapiens OX=9606 GN=TFAP4 PE=1 SV=2 8.75 1950.6 - 978511 - - - -1.1394 - 1.436 0.219 - 176.3 1 2 0 -0.0012 9 0 0 0 1.37E+08 8.50E+07 - - - 1.705 0.999 221125_WJC_METTL3_EV_vs_WT_F03.07592.07592.2 0.0151 16-Aug K.ETGVPIAGR.H "sp|P11586|C1TC_HUMAN,tr|F5H2F4|F5H2F4_HUMAN,tr|V9GZ78|V9GZ78_HUMAN,tr|V9GYY3|V9GYY3_HUMAN" 4 898.4872 1.41 25565 7592 2 898.486619 450.2509 "C-1-tetrahydrofolate synthase, cytoplasmic OS=Homo sapiens OX=9606 GN=MTHFD1 PE=1 SV=4" 6.1 1950.9 - 6.46E+06 - - - -0.68 - 1.581 0.275 - 196.9 1 2 0 -0.0006 9 0 0 0 3.78E+08 2.69E+08 - - - 2.3971 0.984 221125_WJC_METTL3_EV_vs_WT_F03.07602.07602.2 0.387 14-Jul R.ELTAVVQK.R "sp|P23396|RS3_HUMAN,tr|E9PL09|E9PL09_HUMAN,tr|E9PK82|E9PK82_HUMAN,tr|F2Z2S8|F2Z2S8_HUMAN,tr|H0YCJ7|H0YCJ7_HUMAN,tr|E9PQ96|E9PQ96_HUMAN,tr|E9PJH4|E9PJH4_HUMAN,tr|E9PPU1|E9PPU1_HUMAN,tr|H0YF32|H0YF32_HUMAN" 9 886.5124 0.7 25569 7602 2 886.511204 444.2635 40S ribosomal protein S3 OS=Homo sapiens OX=9606 GN=RPS3 PE=1 SV=2 6.1 1952.2 - 2.15E+06 - - - -1.3299 - 1.251 0.11 - 154 1 2 0 -0.0012 8 0 0 0 1.79E+09 2.58E+09 - - - 0.5285 0.9998 221125_WJC_METTL3_EV_vs_WT_F03.07603.07603.2 9.62E-05 16-Oct K.TAVC[160.03]DIPPR[166.11].G "sp|P04350|TBB4A_HUMAN,sp|Q9BVA1|TBB2B_HUMAN,sp|A6NNZ2|TBB8B_HUMAN,sp|P07437|TBB5_HUMAN,sp|Q13885|TBB2A_HUMAN,sp|P68371|TBB4B_HUMAN,sp|Q3ZCM7|TBB8_HUMAN,tr|Q5ST81|Q5ST81_HUMAN,tr|Q5JP53|Q5JP53_HUMAN,tr|A0A075B736|A0A075B736_HUMAN,tr|Q5SQY0|Q5SQY0_HUMAN" 11 1037.5203 0.44 25570 7603 2 1037.520876 519.7674 Tubulin beta-4A chain OS=Homo sapiens OX=9606 GN=TUBB4A PE=1 SV=2 5.5 1952.3 - 751572 - - - 0.5214 - 1.909 0.426 - 541.9 1 2 0 0.0005 9 0 0 0 1.29E+07 2.96E+07 - - - 4.0579 0.9987 221125_WJC_METTL3_EV_vs_WT_F03.07610.07610.2 0.0418 14-Jul R.ELTAVVQK[136.11].R "sp|P23396|RS3_HUMAN,tr|E9PL09|E9PL09_HUMAN,tr|E9PK82|E9PK82_HUMAN,tr|F2Z2S8|F2Z2S8_HUMAN,tr|H0YCJ7|H0YCJ7_HUMAN,tr|E9PQ96|E9PQ96_HUMAN,tr|E9PJH4|E9PJH4_HUMAN,tr|E9PPU1|E9PPU1_HUMAN,tr|H0YF32|H0YF32_HUMAN" 9 894.5266 0.69 25573 7610 2 894.525384 448.2706 40S ribosomal protein S3 OS=Homo sapiens OX=9606 GN=RPS3 PE=1 SV=2 6.1 1953.2 - 9.41E+06 - - - -1.3404 - 1.447 0.309 - 225.1 1 2 0 -0.0012 8 0 0 0 1.79E+09 2.58E+09 - - - 2.4373 0.9956 221125_WJC_METTL3_EV_vs_WT_F03.07618.07618.2 0.0883 16-Oct R.LLQQNTQLK.R "sp|Q01664|TFAP4_HUMAN,tr|I3L254|I3L254_HUMAN" 2 1084.6241 1.62 25576 7618 2 1084.622955 543.3193 Transcription factor AP-4 OS=Homo sapiens OX=9606 GN=TFAP4 PE=1 SV=2 8.75 1954.2 - 4.58E+06 - - - -1.0169 - 1.41 0.176 - 150.2 1 2 0 -0.0011 9 0 0 0 1.37E+08 8.50E+07 - - - 1.3346 0.9964 221125_WJC_METTL3_EV_vs_WT_F03.07620.07620.2 1.49 12-Jul R.FSGVPDR.F "sp|A0A075B6R9|KVD24_HUMAN,sp|A0A0C4DH68|KV224_HUMAN,sp|A2NJV5|KV229_HUMAN,sp|A0A075B6S2|KVD29_HUMAN,sp|A0A0A0MRZ7|KVD26_HUMAN" 5 776.3817 7449.32 25577 7620 2 776.38073 389.1981 Probable non-functional immunoglobulin kappa variable 2D-24 OS=Homo sapiens OX=9606 GN=IGKV2D-24 PE=1 SV=1 5.84 1954.4 - 9.39E+07 - - - -1.2532 - 1.515 0.163 - 159.9 1 2 0 -0.001 7 0 0 0 9.73E+11 1.31E+08 - - - 1.5609 0.9962 221125_WJC_METTL3_EV_vs_WT_F03.07635.07635.2 0.0591 16-Jul R.EVAEGGLPR.A "sp|Q9BUA3|SPNDC_HUMAN,tr|H0YGK9|H0YGK9_HUMAN,tr|H0YGY5|H0YGY5_HUMAN" 3 926.4821 2.47 25586 7635 2 926.481478 464.2483 Spindlin interactor and repressor of chromatin-binding protein OS=Homo sapiens OX=9606 GN=SPINDOC PE=1 SV=3 4.53 1956.1 - 4.11E+06 - - - -0.7199 - 1.443 0.17 - 193.3 1 2 0 -0.0007 9 0 0 0 4.21E+08 1.70E+08 - - - 1.3574 0.9664 221125_WJC_METTL3_EV_vs_WT_F03.07636.07636.2 1.11 18-Jun R.ILPDSGGVAK.T sp|A5YKK6|CNOT1_HUMAN 1 955.5338 0.79 25587 7636 2 955.530837 478.7742 CCR4-NOT transcription complex subunit 1 OS=Homo sapiens OX=9606 GN=CNOT1 PE=1 SV=2 5.84 1956.2 - 724260 - - - -3.149 - 1.162 0.21 - 85.3 2 2 0 -0.003 10 0 0 0 1.89E+07 2.40E+07 - - - 0.8757 0.9909 221125_WJC_METTL3_EV_vs_WT_F03.07637.07637.2 0.105 16-Aug K.AFTQSSTLR.Q "sp|Q6ZN55|ZN574_HUMAN,tr|A0A0C4DFM2|A0A0C4DFM2_HUMAN" 2 1009.5193 0.77 25588 7637 2 1009.516152 505.7669 Zinc finger protein 574 OS=Homo sapiens OX=9606 GN=ZNF574 PE=1 SV=2 9.79 1956.3 - 606854 - - - -3.0777 - 1.386 0.248 - 213.7 1 2 0 -0.0031 9 0 0 0 1.48E+07 1.93E+07 - - - 1.8161 0.9906 221125_WJC_METTL3_EV_vs_WT_F03.07640.07640.2 0.0478 12-Jul R.C[160.03]ILQDGR[166.11].L "sp|P63162|RSMN_HUMAN,sp|P14678|RSMB_HUMAN,tr|J3KRY3|J3KRY3_HUMAN,tr|J3QLE5|J3QLE5_HUMAN,tr|S4R3P3|S4R3P3_HUMAN" 5 870.4257 0.7 25589 7640 2 870.423915 436.2201 Small nuclear ribonucleoprotein-associated protein N OS=Homo sapiens OX=9606 GN=SNRPN PE=1 SV=1 5.83 1956.7 - 1.70E+07 - - - -2.0588 - 1.462 0.133 - 244.8 1 2 0 -0.0018 7 0 0 0 4.52E+08 6.43E+08 - - - 1.2262 0.9993 221125_WJC_METTL3_EV_vs_WT_F03.07642.07642.2 0.00101 16-Aug K.AFTQSSTLR[166.11].Q "sp|Q6ZN55|ZN574_HUMAN,tr|A0A0C4DFM2|A0A0C4DFM2_HUMAN" 2 1019.5275 0.77 25591 7642 2 1019.525988 510.771 Zinc finger protein 574 OS=Homo sapiens OX=9606 GN=ZNF574 PE=1 SV=2 9.79 1956.9 - 866199 - - - -1.5115 - 1.465 0.406 - 274 1 2 0 -0.0015 9 0 0 0 1.48E+07 1.93E+07 - - - 3.144 0.9706 221125_WJC_METTL3_EV_vs_WT_F03.07643.07643.2 0.171 18-Aug R.LLVSASQDGK[136.11].L "sp|P62879|GBB2_HUMAN,sp|Q9HAV0|GBB4_HUMAN,sp|P16520|GBB3_HUMAN,sp|P62873|GBB1_HUMAN,tr|A0A6Q8PFV8|A0A6Q8PFV8_HUMAN,tr|A0A6Q8PFW8|A0A6Q8PFW8_HUMAN,tr|F6X3N5|F6X3N5_HUMAN,tr|F5H8J8|F5H8J8_HUMAN,tr|C9JZN1|C9JZN1_HUMAN,tr|F6UT28|F6UT28_HUMAN,tr|H7C5J5|H7C5J5_HUMAN,tr|E9PCP0|E9PCP0_HUMAN,tr|C9JIS1|C9JIS1_HUMAN,tr|A0A6Q8PG88|A0A6Q8PG88_HUMAN,tr|B1AKQ8|B1AKQ8_HUMAN,tr|F5H0S8|F5H0S8_HUMAN,tr|E7EP32|E7EP32_HUMAN,tr|A0A7I2S2S9|A0A7I2S2S9_HUMAN,tr|F5H100|F5H100_HUMAN,tr|C9JXA5|C9JXA5_HUMAN,tr|A0A6Q8PFE0|A0A6Q8PFE0_HUMAN,tr|C9JD14|C9JD14_HUMAN" 22 1024.5644 1.13 25592 7643 2 1024.563128 513.2895 Guanine nucleotide-binding protein G(I)\G(S)\G(T) subunit beta-2 OS=Homo sapiens OX=9606 GN=GNB2 PE=1 SV=3 5.84 1957 - 337677 - - - -1.2659 - 1.377 0.041 - 62.6 2 2 0 -0.0013 10 0 0 0 2.14E+08 1.89E+08 - - - 0.1019 0.9985 221125_WJC_METTL3_EV_vs_WT_F03.07653.07653.2 0.357 16-Oct K.LGVTANDVK.N "sp|P40925|MDHC_HUMAN,tr|C9JF79|C9JF79_HUMAN,tr|A0A5K1VW95|A0A5K1VW95_HUMAN,tr|B8ZZ51|B8ZZ51_HUMAN,tr|B9A041|B9A041_HUMAN" 5 915.5025 1.19 25598 7653 2 915.501877 458.7585 "Malate dehydrogenase, cytoplasmic OS=Homo sapiens OX=9606 GN=MDH1 PE=1 SV=4" 5.84 1958.2 - 1.43E+06 - - - -0.7307 - 1.824 0.179 - 223.4 1 2 0 -0.0007 9 0 0 0 6.54E+07 5.48E+07 - - - 2.1017 0.9743 221125_WJC_METTL3_EV_vs_WT_F03.07654.07654.2 0.013 12-Jul K.FAEMEER[166.11].F "sp|Q14839|CHD4_HUMAN,tr|A0A2U3TZM0|A0A2U3TZM0_HUMAN,tr|A0A2R8Y685|A0A2R8Y685_HUMAN,tr|A0A2R8Y445|A0A2R8Y445_HUMAN,tr|A0A2R8YD40|A0A2R8YD40_HUMAN,tr|A0A2R8Y5J0|A0A2R8Y5J0_HUMAN,tr|A0A2R8Y425|A0A2R8Y425_HUMAN,tr|A0A2R8YFK9|A0A2R8YFK9_HUMAN,tr|A0A2R8Y8B3|A0A2R8Y8B3_HUMAN,tr|A0A2R8Y8C1|A0A2R8Y8C1_HUMAN,tr|A0A0C4DGG9|A0A0C4DGG9_HUMAN,tr|A0A2R8YFD8|A0A2R8YFD8_HUMAN,tr|A0A2R8Y5Z7|A0A2R8Y5Z7_HUMAN,tr|F5GWX5|F5GWX5_HUMAN,tr|A0A2R8YER1|A0A2R8YER1_HUMAN,tr|A0A2R8Y521|A0A2R8Y521_HUMAN,tr|A0A2R8YDJ9|A0A2R8YDJ9_HUMAN,tr|A0A2R8Y212|A0A2R8Y212_HUMAN" 18 920.3937 0.64 25599 7654 2 920.390503 461.2041 Chromodomain-helicase-DNA-binding protein 4 OS=Homo sapiens OX=9606 GN=CHD4 PE=1 SV=2 4.25 1958.2 - 1.38E+06 - - - -3.5148 - 1.252 0.204 - 166.1 1 2 0 -0.0032 7 0 0 0 4.53E+07 7.04E+07 - - - 1.2588 0.9999 221125_WJC_METTL3_EV_vs_WT_F03.07655.07655.2 0.0401 13/20 R.AAAAVVAAAAR[166.11].T sp|Q8WWH5|TRUB1_HUMAN 1 950.5537 0.55 25600 7655 2 950.553379 476.2841 Probable tRNA pseudouridine synthase 1 OS=Homo sapiens OX=9606 GN=TRUB1 PE=1 SV=1 9.79 1958.4 - 1.11E+06 - - - -0.3209 - 2.694 0.415 - 943.2 1 2 0 -0.0003 11 0 0 0 1.48E+07 2.70E+07 - - - 4.7871 0.9504 221125_WJC_METTL3_EV_vs_WT_F03.07658.07658.2 0.0152 16-Aug R.YGMGTSVER.A sp|P08559|ODPA_HUMAN 1 998.4491 0.92 25601 7658 2 998.455665 500.2318 "Pyruvate dehydrogenase E1 component subunit alpha, somatic form, mitochondrial OS=Homo sapiens OX=9606 GN=PDHA1 PE=1 SV=3" 6 1958.8 - 672016 - - - 6.5452 - 1.374 0.332 - 133.5 1 2 0 0.0065 9 0 0 0 1.74E+07 1.88E+07 - - - 2.4103 0.9971 221125_WJC_METTL3_EV_vs_WT_F03.07662.07662.2 0.575 12-Jun K.TLLESER.E "sp|O75792|RNH2A_HUMAN,sp|P62857|RS28_HUMAN,sp|Q86U38|NOP9_HUMAN,tr|A0A3B3ISH6|A0A3B3ISH6_HUMAN,tr|A0A2R8Y658|A0A2R8Y658_HUMAN" 5 846.4447 8.14 25603 7662 2 846.444181 424.2296 Ribonuclease H2 subunit A OS=Homo sapiens OX=9606 GN=RNASEH2A PE=1 SV=2 4.53 1959.2 - 8.65E+06 - - - -0.6096 - 1.142 0.282 - 112.2 1 2 0 -0.0005 7 0 0 0 2.55E+08 3.13E+07 - - - 1.5444 0.9935 221125_WJC_METTL3_EV_vs_WT_F03.07663.07663.2 0.00646 18-Oct R.LLVSASQDGK.L "sp|P62879|GBB2_HUMAN,sp|Q9HAV0|GBB4_HUMAN,sp|P16520|GBB3_HUMAN,sp|P62873|GBB1_HUMAN,tr|A0A6Q8PFV8|A0A6Q8PFV8_HUMAN,tr|A0A6Q8PFW8|A0A6Q8PFW8_HUMAN,tr|F6X3N5|F6X3N5_HUMAN,tr|F5H8J8|F5H8J8_HUMAN,tr|C9JZN1|C9JZN1_HUMAN,tr|F6UT28|F6UT28_HUMAN,tr|H7C5J5|H7C5J5_HUMAN,tr|E9PCP0|E9PCP0_HUMAN,tr|C9JIS1|C9JIS1_HUMAN,tr|A0A6Q8PG88|A0A6Q8PG88_HUMAN,tr|B1AKQ8|B1AKQ8_HUMAN,tr|F5H0S8|F5H0S8_HUMAN,tr|E7EP32|E7EP32_HUMAN,tr|A0A7I2S2S9|A0A7I2S2S9_HUMAN,tr|F5H100|F5H100_HUMAN,tr|C9JXA5|C9JXA5_HUMAN,tr|A0A6Q8PFE0|A0A6Q8PFE0_HUMAN,tr|C9JD14|C9JD14_HUMAN" 22 1016.5502 1.13 25604 7663 2 1016.545915 509.2824 Guanine nucleotide-binding protein G(I)\G(S)\G(T) subunit beta-2 OS=Homo sapiens OX=9606 GN=GNB2 PE=1 SV=3 5.84 1959.3 - 737459 - - - -4.2398 - 1.92 0.271 - 268.9 1 2 0 -0.0043 10 0 0 0 2.15E+08 1.90E+08 - - - 2.8621 0.991 221125_WJC_METTL3_EV_vs_WT_F03.07664.07664.2 0.0015 16-Aug R.YGMGTSVER[166.11].A sp|P08559|ODPA_HUMAN 1 1008.4574 1.09 25605 7664 2 1008.453002 505.236 "Pyruvate dehydrogenase E1 component subunit alpha, somatic form, mitochondrial OS=Homo sapiens OX=9606 GN=PDHA1 PE=1 SV=3" 6 1959.4 - 757302 - - - -4.3611 - 1.371 0.363 - 194.6 1 2 0 -0.0044 9 0 0 0 3.00E+07 2.76E+07 - - - 2.6336 0.9998 221125_WJC_METTL3_EV_vs_WT_F03.07667.07667.2 0.0586 14-Oct K.VGEVIVTK.D "sp|P10809|CH60_HUMAN,tr|A0A7I2V2X6|A0A7I2V2X6_HUMAN,tr|A0A7I2YQK6|A0A7I2YQK6_HUMAN,tr|A0A7I2V599|A0A7I2V599_HUMAN" 4 843.5066 1.22 25606 7667 2 843.506362 422.7606 "60 kDa heat shock protein, mitochondrial OS=Homo sapiens OX=9606 GN=HSPD1 PE=1 SV=2" 5.97 1959.8 - 1.60E+07 - - - -0.2454 - 2.204 0.333 - 260.6 1 2 0 -0.0002 8 0 0 0 1.70E+10 1.39E+10 - - - 3.8839 0.949 221125_WJC_METTL3_EV_vs_WT_F03.07671.07671.2 0.00727 16-Aug K.SVVGTSSLR.R "sp|P08397|HEM3_HUMAN,tr|F5GY90|F5GY90_HUMAN,tr|A0A3F2YNY7|A0A3F2YNY7_HUMAN,tr|A0A3B3IRR1|A0A3B3IRR1_HUMAN,tr|A0A3B3IU34|A0A3B3IU34_HUMAN,tr|F5H226|F5H226_HUMAN,tr|F5H345|F5H345_HUMAN,tr|A0A3B3IU56|A0A3B3IU56_HUMAN,tr|F5H0P4|F5H0P4_HUMAN,tr|A0A1W2PNU5|A0A1W2PNU5_HUMAN" 10 904.4978 0.77 25610 7671 2 904.49206 453.2562 Porphobilinogen deaminase OS=Homo sapiens OX=9606 GN=HMBS PE=1 SV=2 9.47 1960.1 - 1.57E+06 - - - -6.3405 - 1.385 0.313 - 218.1 1 2 0 -0.0057 9 0 0 0 4.15E+07 5.37E+07 - - - 2.2933 0.9982 221125_WJC_METTL3_EV_vs_WT_F03.07677.07677.2 0.00561 18-Sep R.SLQSENAALR[166.11].L "sp|Q13948|CASP_HUMAN,sp|P39880|CUX1_HUMAN,tr|A0A2R8Y852|A0A2R8Y852_HUMAN,tr|A0A2R8YDI1|A0A2R8YDI1_HUMAN" 4 1097.5705 1.84 25614 7677 2 1097.573454 549.7925 Protein CASP OS=Homo sapiens OX=9606 GN=CUX1 PE=1 SV=2 5.72 1960.9 - 516773 - - - 2.7315 - 1.622 0.361 - 253.8 1 2 0 0.003 10 0 0 0 6.19E+07 3.36E+07 - - - 3.0564 0.9992 221125_WJC_METTL3_EV_vs_WT_F03.07687.07687.2 0.5 18-Aug R.IGSLASGNVR[166.11].S "sp|Q9H2P0|ADNP_HUMAN,tr|A0A2R8Y6X0|A0A2R8Y6X0_HUMAN,tr|A0A669KBJ7|A0A669KBJ7_HUMAN" 3 982.5435 1.08 25620 7687 2 982.54233 492.279 Activity-dependent neuroprotector homeobox protein OS=Homo sapiens OX=9606 GN=ADNP PE=1 SV=1 9.75 1962.1 - 1.21E+06 - - - -1.204 - 1.911 0.276 - 190.3 1 2 0 -0.0012 10 0 0 0 1.58E+08 1.46E+08 - - - 2.8869 0.9998 221125_WJC_METTL3_EV_vs_WT_F03.07688.07688.2 0.000637 16-Aug R.LTAEEMDER[166.11].R "sp|P46940|IQGA1_HUMAN,tr|H0YLE8|H0YLE8_HUMAN,tr|A0A087X225|A0A087X225_HUMAN,tr|A0A0J9YXZ5|A0A0J9YXZ5_HUMAN" 4 1102.484 1.05 25621 7688 2 1102.484931 552.2493 Ras GTPase-activating-like protein IQGAP1 OS=Homo sapiens OX=9606 GN=IQGAP1 PE=1 SV=1 4 1962.3 - 883579 - - - 0.8363 - 1.718 0.5 - 224.8 1 2 0 0.0009 9 0 0 0 3.45E+07 3.28E+07 - - - 4.2993 0.9997 221125_WJC_METTL3_EV_vs_WT_F03.07691.07691.2 0.0308 14-Oct K.VGEVIVTK[136.11].D "sp|P10809|CH60_HUMAN,tr|A0A7I2V2X6|A0A7I2V2X6_HUMAN,tr|A0A7I2YQK6|A0A7I2YQK6_HUMAN,tr|A0A7I2V599|A0A7I2V599_HUMAN" 4 851.5208 1.22 25622 7691 2 851.520426 426.7677 "60 kDa heat shock protein, mitochondrial OS=Homo sapiens OX=9606 GN=HSPD1 PE=1 SV=2" 5.97 1962.7 - 1.30E+08 - - - -0.4028 - 2.142 0.298 - 288.5 1 2 0 -0.0003 8 0 0 0 1.70E+10 1.39E+10 - - - 3.5393 0.9977 221125_WJC_METTL3_EV_vs_WT_F03.07693.07693.2 0.0869 12-Jun R.VAAEDWK.K "sp|P01876|IGHA1_HUMAN,sp|P01877|IGHA2_HUMAN,tr|A0A286YEY1|A0A286YEY1_HUMAN,tr|A0A0G2JMB2|A0A0G2JMB2_HUMAN,tr|A0A286YEY5|A0A286YEY5_HUMAN" 5 817.397 6.15 25624 7693 2 817.395788 409.7058 Immunoglobulin heavy constant alpha 1 OS=Homo sapiens OX=9606 GN=IGHA1 PE=1 SV=2 4.37 1962.8 - 2.20E+06 - - - -1.5048 - 1.391 0.265 - 114.1 1 2 0 -0.0012 7 0 0 0 1.92E+08 3.12E+07 - - - 2.0436 0.999 221125_WJC_METTL3_EV_vs_WT_F03.07694.07694.2 0.0337 18-Aug R.SLQSENAALR.L "sp|Q13948|CASP_HUMAN,sp|P39880|CUX1_HUMAN,tr|A0A2R8Y852|A0A2R8Y852_HUMAN,tr|A0A2R8YDI1|A0A2R8YDI1_HUMAN" 4 1087.5622 1.84 25625 7694 2 1087.561553 544.7884 Protein CASP OS=Homo sapiens OX=9606 GN=CUX1 PE=1 SV=2 5.72 1962.8 - 1.78E+06 - - - -0.582 - 1.664 0.264 - 184.9 1 2 0 -0.0006 10 0 0 0 6.19E+07 3.36E+07 - - - 2.4121 0.9998 221125_WJC_METTL3_EV_vs_WT_F03.07695.07695.2 0.0086 18-Oct R.IGSLASGNVR.S "sp|Q9H2P0|ADNP_HUMAN,tr|A0A2R8Y6X0|A0A2R8Y6X0_HUMAN,tr|A0A669KBJ7|A0A669KBJ7_HUMAN" 3 972.5352 1.13 25626 7695 2 972.534192 487.2749 Activity-dependent neuroprotector homeobox protein OS=Homo sapiens OX=9606 GN=ADNP PE=1 SV=1 9.75 1962.9 - 1.39E+06 - - - -1.0807 - 2.23 0.414 - 288.6 1 2 0 -0.0011 10 0 0 0 1.67E+08 1.48E+08 - - - 4.3371 0.9997 221125_WJC_METTL3_EV_vs_WT_F03.07696.07696.2 0.000297 26-Oct R.GNLGAGNGNLQGPR.H "sp|P43243|MATR3_HUMAN,tr|D6RE02|D6RE02_HUMAN,tr|B3KM87|B3KM87_HUMAN,tr|A8MXP9|A8MXP9_HUMAN,tr|D6RAY2|D6RAY2_HUMAN,tr|D6R991|D6R991_HUMAN,tr|A0A0R4J2E8|A0A0R4J2E8_HUMAN,tr|D6RAM9|D6RAM9_HUMAN,tr|D6RIA2|D6RIA2_HUMAN,tr|H0Y8T4|H0Y8T4_HUMAN,tr|D6REM6|D6REM6_HUMAN,tr|D6RBI2|D6RBI2_HUMAN" 12 1323.6644 3.09 25627 7696 2 1323.66563 662.8395 Matrin-3 OS=Homo sapiens OX=9606 GN=MATR3 PE=1 SV=2 9.75 1963.1 - 367417 - - - 0.9595 - 1.802 0.452 - 114.9 1 2 0 0.0013 14 0 0 0 1.89E+07 6.13E+06 - - - 3.8569 0.9971 221125_WJC_METTL3_EV_vs_WT_F03.07699.07699.2 0.292 12-Jun K.EEIAEYR.R "sp|P07197|NFM_HUMAN,tr|E7ESP9|E7ESP9_HUMAN,tr|E7EMV2|E7EMV2_HUMAN" 3 908.424 2.12 25628 7699 2 908.422791 455.2193 Neurofilament medium polypeptide OS=Homo sapiens OX=9606 GN=NEFM PE=1 SV=3 4.25 1963.5 - 2.40E+06 - - - -1.289 - 1.214 0.284 - 173.3 1 2 0 -0.0012 7 0 0 0 1.22E+08 5.75E+07 - - - 1.7527 0.9727 221125_WJC_METTL3_EV_vs_WT_F03.07700.07700.2 5.02 12-Jun K.ELATLQR.Q "sp|P46940|IQGA1_HUMAN,tr|A0A0J9YXZ5|A0A0J9YXZ5_HUMAN" 2 829.4658 1.01 25629 7700 2 829.464049 415.7402 Ras GTPase-activating-like protein IQGAP1 OS=Homo sapiens OX=9606 GN=IQGAP1 PE=1 SV=1 6.1 1963.5 - 1.92E+06 - - - -2.0712 - 1.319 0.095 - 132.3 2 2 0 -0.0017 7 0 0 0 9.70E+07 9.63E+07 - - - 0.485 0.9962 221125_WJC_METTL3_EV_vs_WT_F03.07701.07701.2 0.131 14-Aug R.EAESLIAK.K "sp|P78371|TCPB_HUMAN,tr|F8VQ14|F8VQ14_HUMAN,tr|F5GWF6|F5GWF6_HUMAN" 3 859.4651 0.53 25630 7701 2 859.463375 430.7398 T-complex protein 1 subunit beta OS=Homo sapiens OX=9606 GN=CCT2 PE=1 SV=4 4.53 1963.6 - 8.16E+06 - - - -2.0047 - 1.311 0.275 - 214.2 1 2 0 -0.0017 8 0 0 0 2.29E+09 4.32E+09 - - - 1.8883 0.9948 221125_WJC_METTL3_EV_vs_WT_F03.07704.07704.2 0.414 14-Jul R.IIAQC[160.03]LNK[136.11].M "sp|O75306|NDUS2_HUMAN,tr|A0A7I2V4X8|A0A7I2V4X8_HUMAN,tr|A0A7I2V4G5|A0A7I2V4G5_HUMAN,tr|A0A7I2YQG7|A0A7I2YQG7_HUMAN,tr|A0A7I2V596|A0A7I2V596_HUMAN,tr|A0A7I2V410|A0A7I2V410_HUMAN,tr|A0A7I2V630|A0A7I2V630_HUMAN,tr|A0A7I2V2B9|A0A7I2V2B9_HUMAN,tr|A0A7I2YQD8|A0A7I2YQD8_HUMAN,tr|A0A7I2V3J6|A0A7I2V3J6_HUMAN,tr|A0A7I2V4W5|A0A7I2V4W5_HUMAN" 11 966.5412 0.97 25633 7704 2 966.542457 484.2779 "NADH dehydrogenase [ubiquinone] iron-sulfur protein 2, mitochondrial OS=Homo sapiens OX=9606 GN=NDUFS2 PE=1 SV=2" 8.22 1963.9 - 950170 - - - 1.314 - 1.433 0.171 - 96.6 1 2 0 0.0013 8 0 0 0 4.32E+07 4.45E+07 - - - 1.3887 0.9997 221125_WJC_METTL3_EV_vs_WT_F03.07705.07705.2 0.000435 16-Aug R.LTAEEMDER.R "sp|P46940|IQGA1_HUMAN,tr|H0YLE8|H0YLE8_HUMAN,tr|A0A087X225|A0A087X225_HUMAN,tr|A0A0J9YXZ5|A0A0J9YXZ5_HUMAN" 4 1092.4757 1.05 25634 7705 2 1092.475284 547.2451 Ras GTPase-activating-like protein IQGAP1 OS=Homo sapiens OX=9606 GN=IQGAP1 PE=1 SV=1 4 1964 - 670032 - - - -0.4165 - 1.925 0.385 - 287.9 1 2 0 -0.0005 9 0 0 0 3.45E+07 3.28E+07 - - - 3.7792 0.9873 221125_WJC_METTL3_EV_vs_WT_F03.07708.07708.2 0.275 16-Aug R.SLLEGQDAK.M "sp|P19012|K1C15_HUMAN,sp|P13646|K1C13_HUMAN,tr|K7ERE3|K7ERE3_HUMAN,tr|A8MT21|A8MT21_HUMAN" 4 959.4924 0.81 25635 7708 2 959.490413 480.7535 "Keratin, type I cytoskeletal 15 OS=Homo sapiens OX=9606 GN=KRT15 PE=1 SV=3" 4.37 1964.4 - 1.39E+06 - - - -2.0448 - 1.274 0.171 - 140.4 1 2 0 -0.002 9 0 0 0 6.05E+07 7.46E+07 - - - 1.004 0.9904 221125_WJC_METTL3_EV_vs_WT_F03.07710.07710.2 0.165 12-Jul R.MVEIGSR.W "sp|P17480|UBF1_HUMAN,tr|E9PKP7|E9PKP7_HUMAN,tr|E9PLT2|E9PLT2_HUMAN" 3 790.4007 2.11 25637 7710 2 790.400667 396.2076 Nucleolar transcription factor 1 OS=Homo sapiens OX=9606 GN=UBTF PE=1 SV=1 5.75 1964.6 - 1.60E+06 - - - -0.0721 - 1.273 0.113 - 209 1 2 0 -0.0001 7 0 0 0 1.56E+08 7.42E+07 - - - 0.6404 0.9942 221125_WJC_METTL3_EV_vs_WT_F03.07711.07711.2 0.0319 12-Jul K.EEIAEYR[166.11].R "sp|P07197|NFM_HUMAN,tr|E7ESP9|E7ESP9_HUMAN,tr|E7EMV2|E7EMV2_HUMAN" 3 918.4322 2.34 25638 7711 2 918.430909 460.2234 Neurofilament medium polypeptide OS=Homo sapiens OX=9606 GN=NEFM PE=1 SV=3 4.25 1964.6 - 1.19E+06 - - - -1.4405 - 1.077 0.273 - 129.6 1 2 0 -0.0013 7 0 0 0 1.07E+08 4.56E+07 - - - 1.292 0.9982 221125_WJC_METTL3_EV_vs_WT_F03.07714.07714.2 0.0475 14-Aug R.EAESLIAK[136.11].K "sp|P78371|TCPB_HUMAN,tr|F8VQ14|F8VQ14_HUMAN,tr|F5GWF6|F5GWF6_HUMAN" 3 867.4793 0.53 25639 7714 2 867.476977 434.7469 T-complex protein 1 subunit beta OS=Homo sapiens OX=9606 GN=CCT2 PE=1 SV=4 4.53 1965 - 3.37E+07 - - - -2.6756 - 1.576 0.349 - 340.8 1 2 0 -0.0023 8 0 0 0 2.28E+09 4.30E+09 - - - 2.9899 0.9629 221125_WJC_METTL3_EV_vs_WT_F03.07716.07716.2 3.15 16-Jul K.ILTTGENYK[136.11].T "sp|Q13490|BIRC2_HUMAN,tr|E9PMH5|E9PMH5_HUMAN,tr|E9PIW1|E9PIW1_HUMAN,tr|A0A087X2B2|A0A087X2B2_HUMAN" 4 1045.5535 0.001 25640 7716 2 1045.553627 523.784 Baculoviral IAP repeat-containing protein 2 OS=Homo sapiens OX=9606 GN=BIRC2 PE=1 SV=2 6 1965.2 - 0 - - - 0.0966 - 1.128 0.05 - 94.5 1 2 0 0.0001 9 0 0 0 0.00E+00 4.51E+06 - - - -0.2413 0.9884 221125_WJC_METTL3_EV_vs_WT_F03.07718.07718.2 0.0746 14-Jul R.IIAQC[160.03]LNK.M "sp|O75306|NDUS2_HUMAN,tr|A0A7I2V4X8|A0A7I2V4X8_HUMAN,tr|A0A7I2V4G5|A0A7I2V4G5_HUMAN,tr|A0A7I2YQG7|A0A7I2YQG7_HUMAN,tr|A0A7I2V596|A0A7I2V596_HUMAN,tr|A0A7I2V410|A0A7I2V410_HUMAN,tr|A0A7I2V630|A0A7I2V630_HUMAN,tr|A0A7I2V2B9|A0A7I2V2B9_HUMAN,tr|A0A7I2YQD8|A0A7I2YQD8_HUMAN,tr|A0A7I2V3J6|A0A7I2V3J6_HUMAN,tr|A0A7I2V4W5|A0A7I2V4W5_HUMAN" 11 958.527 0.97 25641 7718 2 958.525078 480.2708 "NADH dehydrogenase [ubiquinone] iron-sulfur protein 2, mitochondrial OS=Homo sapiens OX=9606 GN=NDUFS2 PE=1 SV=2" 8.22 1965.4 - 1.66E+06 - - - -1.9916 - 1.165 0.209 - 106.2 1 2 0 -0.0019 8 0 0 0 4.32E+07 4.45E+07 - - - 1.0447 0.9559 221125_WJC_METTL3_EV_vs_WT_F03.07722.07722.2 0.539 12-May K.VDNLTYR[166.11].T "sp|Q01130|SRSF2_HUMAN,sp|Q9BRL6|SRSF8_HUMAN,tr|J3KP15|J3KP15_HUMAN,tr|J3QL05|J3QL05_HUMAN" 4 889.4533 1.11 25642 7722 2 889.450691 445.7339 Serine\arginine-rich splicing factor 2 OS=Homo sapiens OX=9606 GN=SRSF2 PE=1 SV=4 5.81 1966 - 3.91E+06 - - - -2.9344 - 1.418 0.087 - 79.1 3 2 0 -0.0026 7 0 0 0 2.02E+08 1.82E+08 - - - 0.5762 0.9805 221125_WJC_METTL3_EV_vs_WT_F03.07730.07730.2 3.13 14-Jul R.STYVTEVR.E "sp|Q86UP2|KTN1_HUMAN,tr|B7Z6P3|B7Z6P3_HUMAN,tr|H0YJP2|H0YJP2_HUMAN,tr|G3V4Y7|G3V4Y7_HUMAN" 4 953.4818 1.83 25643 7730 2 953.479484 477.7482 Kinectin OS=Homo sapiens OX=9606 GN=KTN1 PE=1 SV=1 5.72 1967.3 - 716476 - - - -2.4405 - 1.461 0.097 - 254.1 1 2 0 -0.0023 8 0 0 0 1.33E+08 7.26E+07 - - - 0.9001 0.997 221125_WJC_METTL3_EV_vs_WT_F03.07734.07734.2 0.0587 14-Aug R.ELTAVVQK[136.11].R "sp|P23396|RS3_HUMAN,tr|E9PL09|E9PL09_HUMAN,tr|E9PK82|E9PK82_HUMAN,tr|F2Z2S8|F2Z2S8_HUMAN,tr|H0YCJ7|H0YCJ7_HUMAN,tr|E9PQ96|E9PQ96_HUMAN,tr|E9PJH4|E9PJH4_HUMAN,tr|E9PPU1|E9PPU1_HUMAN,tr|H0YF32|H0YF32_HUMAN" 9 894.5266 0.69 25644 7734 2 894.524391 448.2706 40S ribosomal protein S3 OS=Homo sapiens OX=9606 GN=RPS3 PE=1 SV=2 6.1 1967.9 - 3.25E+06 - - - -2.4505 - 1.498 0.285 - 199 1 2 0 -0.0022 8 0 0 0 1.79E+09 2.58E+09 - - - 2.3642 0.8661 221125_WJC_METTL3_EV_vs_WT_F03.07736.07736.2 0.921 14-Jul L.GTEMVITK[136.11].S "sp|Q13207|TBX2_HUMAN,sp|O15119|TBX3_HUMAN,tr|F8WCM9|F8WCM9_HUMAN" 3 885.4721 0.51 25646 7736 2 885.470024 443.7433 T-box transcription factor TBX2 OS=Homo sapiens OX=9606 GN=TBX2 PE=1 SV=3 6 1968 - 3.72E+06 - - - -2.349 - 1.689 0.246 - 226.1 1 1 0 -0.0021 8 0 0 0 1.26E+08 2.49E+08 - - - 2.4381 0.9994 221125_WJC_METTL3_EV_vs_WT_F03.07737.07737.2 0.0163 14-Jul R.GPAYGLSR[166.11].E "sp|P37802|TAGL2_HUMAN,tr|X6RJP6|X6RJP6_HUMAN" 2 829.4322 1.22 25647 7737 2 829.4317 415.7234 Transgelin-2 OS=Homo sapiens OX=9606 GN=TAGLN2 PE=1 SV=3 8.75 1968.1 - 3.05E+06 - - - -0.5691 - 1.463 0.373 - 205.7 1 2 0 -0.0005 8 0 0 0 4.02E+08 3.31E+08 - - - 2.9434 0.9963 221125_WJC_METTL3_EV_vs_WT_F03.07745.07745.2 0.0236 14-Aug R.STYVTEVR[166.11].E "sp|Q86UP2|KTN1_HUMAN,tr|B7Z6P3|B7Z6P3_HUMAN,tr|H0YJP2|H0YJP2_HUMAN,tr|G3V4Y7|G3V4Y7_HUMAN" 4 963.4901 1.64 25649 7745 2 963.489536 482.7523 Kinectin OS=Homo sapiens OX=9606 GN=KTN1 PE=1 SV=1 5.72 1969.2 - 1.16E+06 - - - -0.5657 - 1.586 0.124 - 301.4 1 2 0 -0.0005 8 0 0 0 1.13E+08 6.89E+07 - - - 1.3477 0.9954 221125_WJC_METTL3_EV_vs_WT_F03.07746.07746.2 0.173 14-Aug K.LIQQQLEK[136.11].E "sp|Q9Y5M8|SRPRB_HUMAN,tr|H7C4H2|H7C4H2_HUMAN" 2 1006.5902 1.04 25650 7746 2 1006.590825 504.3024 Signal recognition particle receptor subunit beta OS=Homo sapiens OX=9606 GN=SRPRB PE=1 SV=3 6 1969.3 - 832376 - - - 0.5752 - 1.417 0.156 - 141.2 1 2 0 0.0006 8 0 0 0 2.69E+08 2.59E+08 - - - 1.2442 0.9431 221125_WJC_METTL3_EV_vs_WT_F03.07748.07748.2 0.193 16-Aug K.VLC[160.03]AVSGPR[166.11].Q sp|Q5RKV6|EXOS6_HUMAN 1 967.5149 1.43 25652 7748 2 967.510259 484.7647 Exosome complex component MTR3 OS=Homo sapiens OX=9606 GN=EXOSC6 PE=1 SV=1 8.22 1969.5 - 790015 - - - -4.7513 - 1.423 0.17 - 137.3 1 2 0 -0.0046 9 0 0 0 1.66E+08 1.16E+08 - - - 1.3158 0.9727 221125_WJC_METTL3_EV_vs_WT_F03.07761.07761.2 0.24 12-Jun R.ADAVWNK.L "sp|P42704|LPPRC_HUMAN,tr|A0A804HI14|A0A804HI14_HUMAN,tr|A0A804HL40|A0A804HL40_HUMAN,tr|A0A804HKJ0|A0A804HKJ0_HUMAN,tr|A0A804HKR3|A0A804HKR3_HUMAN,tr|A0A804HIN4|A0A804HIN4_HUMAN,tr|A0A804HJG8|A0A804HJG8_HUMAN,tr|A0A804HLG8|A0A804HLG8_HUMAN,tr|A0A804HI40|A0A804HI40_HUMAN,tr|A0A804HJZ1|A0A804HJZ1_HUMAN,tr|A0A804HIQ7|A0A804HIQ7_HUMAN,tr|A0A804HK30|A0A804HK30_HUMAN,tr|A0A804HKI2|A0A804HKI2_HUMAN,tr|A0A804HJI0|A0A804HJI0_HUMAN,tr|A0A804HIG4|A0A804HIG4_HUMAN" 15 802.3974 0.77 25660 7761 2 802.395483 402.206 "Leucine-rich PPR motif-containing protein, mitochondrial OS=Homo sapiens OX=9606 GN=LRPPRC PE=1 SV=3" 5.88 1970.8 - 3.20E+06 - - - -2.3305 - 1.128 0.161 - 164.7 1 2 0 -0.0019 7 0 0 0 8.29E+07 1.07E+08 - - - 0.6112 0.9986 221125_WJC_METTL3_EV_vs_WT_F03.07770.07770.2 0.0802 16-May R.GLVPPNASR.F sp|P47929|LEG7_HUMAN 1 909.5032 697.06 25664 7770 2 909.502652 455.7589 Galectin-7 OS=Homo sapiens OX=9606 GN=LGALS7 PE=1 SV=2 9.75 1972 - 3.29E+06 - - - -0.619 - 1.31 0.315 - 98.8 1 2 0 -0.0006 9 0 0 0 4.89E+08 7.02E+05 - - - 2.1486 0.9308 221125_WJC_METTL3_EV_vs_WT_F03.07772.07772.2 1.82 14-Jul K.LIQQQLEK.E "sp|Q9Y5M8|SRPRB_HUMAN,tr|H7C4H2|H7C4H2_HUMAN" 2 998.576 1.04 25666 7772 2 998.573621 500.2953 Signal recognition particle receptor subunit beta OS=Homo sapiens OX=9606 GN=SRPRB PE=1 SV=3 6 1972.1 - 3.67E+06 - - - -2.4285 - 1.081 0.101 - 94.6 1 2 0 -0.0024 8 0 0 0 2.69E+08 2.59E+08 - - - 0.0211 0.9797 221125_WJC_METTL3_EV_vs_WT_F03.07776.07776.2 0.929 14-Oct R.LAALEEQR[166.11].M "sp|O00541|PESC_HUMAN,tr|B3KXD6|B3KXD6_HUMAN,tr|B5MCF9|B5MCF9_HUMAN,tr|H7C267|H7C267_HUMAN" 4 938.5061 0.22 25667 7776 2 938.508287 470.2603 Pescadillo homolog OS=Homo sapiens OX=9606 GN=PES1 PE=1 SV=1 4.53 1972.7 - 2.58E+06 - - - 2.3676 - 1.526 0.075 - 344.9 1 2 0 0.0022 8 0 0 0 9.77E+07 4.39E+08 - - - 0.8689 0.998 221125_WJC_METTL3_EV_vs_WT_F03.07787.07787.2 0.12 16-Aug K.ASLVYGSSR[166.11].T sp|Q9ULL5|PRR12_HUMAN 1 948.4904 0.27 25674 7787 2 948.491329 475.2525 Proline-rich protein 12 OS=Homo sapiens OX=9606 GN=PRR12 PE=1 SV=3 8.79 1974 - 689828 - - - 0.9636 - 1.493 0.246 - 185.7 1 2 0 0.0009 9 0 0 0 8.16E+06 2.97E+07 - - - 2.0172 0.9992 221125_WJC_METTL3_EV_vs_WT_F03.07790.07790.2 0.00773 16-Sep R.ALEEAMEQK.A sp|P35579|MYH9_HUMAN 1 1047.4907 1.11 25675 7790 2 1047.490194 524.7526 Myosin-9 OS=Homo sapiens OX=9606 GN=MYH9 PE=1 SV=4 4.25 1974.4 - 3.76E+06 - - - -0.4458 - 1.642 0.289 - 249.7 1 2 0 -0.0005 9 0 0 0 1.42E+08 1.28E+08 - - - 2.6101 0.9407 221125_WJC_METTL3_EV_vs_WT_F03.07799.07799.2 0.138 20-Jul A.VVTGVTAVAQK.T "sp|P37840|SYUA_HUMAN,tr|A0A669KB41|A0A669KB41_HUMAN,tr|A0A669KBH5|A0A669KBH5_HUMAN,tr|H6UYS7|H6UYS7_HUMAN,tr|E7EPV7|E7EPV7_HUMAN" 5 1071.6288 1.74 25679 7799 2 1071.627327 536.8217 Alpha-synuclein OS=Homo sapiens OX=9606 GN=SNCA PE=1 SV=1 8.72 1975.5 - 238128 - - - -1.3829 - 1.496 0.343 - 104 1 1 0 -0.0015 11 0 0 0 1.73E+07 9.93E+06 - - - 2.6636 0.783 221125_WJC_METTL3_EV_vs_WT_F03.07822.07822.2 3 12-Jul R.AIDYVQR.Q "sp|O60637|TSN3_HUMAN,tr|H0YKJ9|H0YKJ9_HUMAN" 2 863.4501 2.91 25687 7822 2 863.445386 432.7323 Tetraspanin-3 OS=Homo sapiens OX=9606 GN=TSPAN3 PE=2 SV=1 5.88 1978.6 - 5.55E+06 - - - -5.4792 - 1.288 0.104 - 143.2 1 2 0 -0.0047 7 0 0 0 9.63E+08 3.31E+08 - - - 0.6096 0.9993 221125_WJC_METTL3_EV_vs_WT_F03.07827.07827.2 0.125 16-Nov K.LVSDTIGQR.V "sp|Q9UPN3|MACF1_HUMAN,tr|A0A804HL78|A0A804HL78_HUMAN,tr|H3BQK9|H3BQK9_HUMAN,tr|A0A7P0MQR8|A0A7P0MQR8_HUMAN,tr|H0Y390|H0Y390_HUMAN,tr|H3BPE1|H3BPE1_HUMAN,tr|A0A590UJG2|A0A590UJG2_HUMAN" 7 987.5349 0.61 25689 7827 2 987.534673 494.7747 "Microtubule-actin cross-linking factor 1, isoforms 1\2\3\5 OS=Homo sapiens OX=9606 GN=MACF1 PE=1 SV=4" 5.84 1979.2 - 1.43E+06 - - - -0.239 - 1.871 0.249 - 415.8 1 2 0 -0.0002 9 0 0 0 5.86E+07 9.66E+07 - - - 2.6925 0.9826 221125_WJC_METTL3_EV_vs_WT_F03.07834.07834.2 1.86 14-Jul R.LTVNEAVK[136.11].E "sp|Q15149|PLEC_HUMAN,tr|H0YDN1|H0YDN1_HUMAN" 2 880.5109 1.56 25693 7834 2 880.510765 441.2627 Plectin OS=Homo sapiens OX=9606 GN=PLEC PE=1 SV=3 6 1980 - 833595 - - - -0.1908 - 1.253 0.071 - 81.7 1 2 0 -0.0002 8 0 0 0 1.14E+08 7.32E+07 - - - 0.2456 0.9998 221125_WJC_METTL3_EV_vs_WT_F03.07835.07835.2 9.85E-05 14-Aug K.VTYMEEER.N "sp|P34932|HSP74_HUMAN,tr|A0A087WTS8|A0A087WTS8_HUMAN,tr|A0A087WYC1|A0A087WYC1_HUMAN" 3 1055.4594 0.07 25694 7835 2 1055.459322 528.737 Heat shock 70 kDa protein 4 OS=Homo sapiens OX=9606 GN=HSPA4 PE=1 SV=4 4.25 1980.1 - 600351 - - - -0.037 - 1.632 0.477 - 219.7 1 2 0 0 8 0 0 0 2.59E+07 3.54E+08 - - - 4.0413 0.9982 221125_WJC_METTL3_EV_vs_WT_F03.07839.07839.2 1.03 14-Jul R.AGLLSQAK[136.11].G sp|Q5RKV6|EXOS6_HUMAN 1 794.4742 0.92 25695 7839 2 794.474341 398.2444 Exosome complex component MTR3 OS=Homo sapiens OX=9606 GN=EXOSC6 PE=1 SV=1 8.8 1980.6 - 2.79E+06 - - - 0.2366 - 1.676 0.196 - 146.9 2 2 0 0.0002 8 0 0 0 1.21E+08 1.32E+08 - - - 1.9116 0.9999 221125_WJC_METTL3_EV_vs_WT_F03.07840.07840.2 4.11E-05 18-Dec R.IGNSGVEEIK.G sp|Q9Y2H1|ST38L_HUMAN 1 1044.5451 3.44 25696 7840 2 1044.546044 523.2798 Serine\threonine-protein kinase 38-like OS=Homo sapiens OX=9606 GN=STK38L PE=1 SV=3 4.53 1980.7 - 1.52E+06 - - - 0.8664 - 2.346 0.508 - 337.5 1 2 0 0.0009 10 0 0 0 3.69E+08 1.07E+08 - - - 5.173 0.9996 221125_WJC_METTL3_EV_vs_WT_F03.07844.07844.2 0.000828 18-Oct R.IGNSGVEEIK[136.11].G sp|Q9Y2H1|ST38L_HUMAN 1 1052.5593 3.44 25698 7844 2 1052.560484 527.2869 Serine\threonine-protein kinase 38-like OS=Homo sapiens OX=9606 GN=STK38L PE=1 SV=3 4.53 1981.2 - 812078 - - - 1.0878 - 2.212 0.311 - 191.1 1 2 0 0.0011 10 0 0 0 3.69E+08 1.07E+08 - - - 3.5537 0.9988 221125_WJC_METTL3_EV_vs_WT_F03.07855.07855.2 0.0386 16-Sep K.TAVC[160.03]DIPPR[166.11].G "sp|P04350|TBB4A_HUMAN,sp|Q9BVA1|TBB2B_HUMAN,sp|A6NNZ2|TBB8B_HUMAN,sp|P07437|TBB5_HUMAN,sp|Q13885|TBB2A_HUMAN,sp|P68371|TBB4B_HUMAN,sp|Q3ZCM7|TBB8_HUMAN,tr|Q5ST81|Q5ST81_HUMAN,tr|Q5JP53|Q5JP53_HUMAN,tr|A0A075B736|A0A075B736_HUMAN,tr|Q5SQY0|Q5SQY0_HUMAN" 11 1037.5203 1.09 25704 7855 2 1037.523206 519.7674 Tubulin beta-4A chain OS=Homo sapiens OX=9606 GN=TUBB4A PE=1 SV=2 5.5 1982.5 - 361002 - - - 2.7672 - 1.83 0.371 - 325.5 1 2 0 0.0029 9 0 0 0 2.92E+07 2.69E+07 - - - 3.5286 0.9945 221125_WJC_METTL3_EV_vs_WT_F03.07859.07859.2 0.24 14-Jul K.ITSFEEAK.G "sp|Q08209|PP2BA_HUMAN,tr|E7ETC2|E7ETC2_HUMAN" 2 923.46 1.61 25706 7859 2 923.460275 462.7373 Serine\threonine-protein phosphatase 2B catalytic subunit alpha isoform OS=Homo sapiens OX=9606 GN=PPP3CA PE=1 SV=1 4.53 1983 - 1.14E+06 - - - 0.2837 - 1.216 0.194 - 148.6 1 2 0 0.0003 8 0 0 0 4.49E+07 2.79E+07 - - - 1.0636 0.9948 221125_WJC_METTL3_EV_vs_WT_F03.07861.07861.2 0.00989 16-Sep K.TVEEVTVER[166.11].N "sp|Q07157|ZO1_HUMAN,tr|A0A087X0K9|A0A087X0K9_HUMAN,tr|G5E9E7|G5E9E7_HUMAN,tr|A0A0G2JNH2|A0A0G2JNH2_HUMAN,tr|G3V1L9|G3V1L9_HUMAN,tr|A0A7I2V5U5|A0A7I2V5U5_HUMAN" 6 1070.5483 1.1 25708 7861 2 1070.552883 536.2814 Tight junction protein ZO-1 OS=Homo sapiens OX=9606 GN=TJP1 PE=1 SV=3 4.25 1983.2 - 252734 - - - 4.2586 - 1.569 0.376 - 274.2 1 2 0 0.0046 9 0 0 0 6.41E+06 5.82E+06 - - - 3.1198 0.9953 221125_WJC_METTL3_EV_vs_WT_F03.07865.07865.2 0.529 16-Aug K.GLAPEVADR[166.11].L "sp|P49590|SYHM_HUMAN,sp|P12081|HARS1_HUMAN,tr|A0A6Q8PF47|A0A6Q8PF47_HUMAN,tr|A0A2R8Y5P7|A0A2R8Y5P7_HUMAN,tr|A0A6Q8PF07|A0A6Q8PF07_HUMAN,tr|B4E1C5|B4E1C5_HUMAN,tr|A0A2R8Y6I1|A0A2R8Y6I1_HUMAN,tr|B4DQ67|B4DQ67_HUMAN,tr|A0A6Q8PHA5|A0A6Q8PHA5_HUMAN,tr|E7ETE2|E7ETE2_HUMAN,tr|D6RB22|D6RB22_HUMAN,tr|A0A2R8Y3N3|A0A2R8Y3N3_HUMAN,tr|A0A6Q8PFF2|A0A6Q8PFF2_HUMAN,tr|A0A6Q8PHE3|A0A6Q8PHE3_HUMAN,tr|B4DDD8|B4DDD8_HUMAN,tr|D6RJE6|D6RJE6_HUMAN" 16 936.4904 0.39 25709 7865 2 936.492327 469.2525 "Histidine--tRNA ligase, mitochondrial OS=Homo sapiens OX=9606 GN=HARS2 PE=1 SV=1" 4.37 1983.8 - 3.81E+06 - - - 2.0417 - 1.573 0.195 - 111.4 1 2 0 0.0019 9 0 0 0 4.49E+07 1.14E+08 - - - 1.7912 0.9994 221125_WJC_METTL3_EV_vs_WT_F03.07867.07867.2 0.0134 16-Aug K.LPQTEQELK[136.11].E "sp|Q9NTJ3|SMC4_HUMAN,tr|E9PD53|E9PD53_HUMAN" 2 1092.5906 0.69 25711 7867 2 1092.590791 547.3026 Structural maintenance of chromosomes protein 4 OS=Homo sapiens OX=9606 GN=SMC4 PE=1 SV=2 4.53 1984.1 - 1.12E+06 - - - 0.1382 - 1.665 0.324 - 250.8 1 2 0 0.0002 9 0 0 0 2.95E+07 4.29E+07 - - - 2.909 0.9708 221125_WJC_METTL3_EV_vs_WT_F03.07868.07868.2 0.358 16-Jun K.LEEGLVNNK[136.11].Y "sp|Q8NI36|WDR36_HUMAN,tr|A0A0A0MTB8|A0A0A0MTB8_HUMAN" 2 1022.5488 1.14 25712 7868 2 1022.548792 512.2817 WD repeat-containing protein 36 OS=Homo sapiens OX=9606 GN=WDR36 PE=1 SV=1 4.53 1984.2 - 297430 - - - 0.0166 - 1.324 0.026 - 76.1 2 2 0 0 9 0 0 0 6.57E+06 5.75E+06 - - - -0.0895 0.9914 221125_WJC_METTL3_EV_vs_WT_F03.07870.07870.2 0.309 14-Jun R.AGLLSQAK.G sp|Q5RKV6|EXOS6_HUMAN 1 786.46 0.9 25713 7870 2 786.45985 394.2373 Exosome complex component MTR3 OS=Homo sapiens OX=9606 GN=EXOSC6 PE=1 SV=1 8.8 1984.4 - 3.06E+06 - - - -0.131 - 1.559 0.064 - 87.2 2 2 0 -0.0001 8 0 0 0 1.14E+08 1.26E+08 - - - 0.7184 0.9952 221125_WJC_METTL3_EV_vs_WT_F03.07872.07872.2 0.174 12-Jul K.IQAEFEK[136.11].K sp|Q12874|SF3A3_HUMAN 1 871.4531 2.26 25714 7872 2 871.453221 436.7338 Splicing factor 3A subunit 3 OS=Homo sapiens OX=9606 GN=SF3A3 PE=1 SV=1 4.53 1984.6 - 7.20E+06 - - - 0.1584 - 1.635 0.091 - 120.5 2 2 0 0.0001 7 0 0 0 1.13E+09 5.01E+08 - - - 1.1364 0.9761 221125_WJC_METTL3_EV_vs_WT_F03.07873.07873.2 0.194 14-Jun R.GLPPSMER.G "sp|P38159|RBMX_HUMAN,tr|H3BUY5|H3BUY5_HUMAN" 2 885.4378 1.64 25715 7873 2 885.43762 443.7262 "RNA-binding motif protein, X chromosome OS=Homo sapiens OX=9606 GN=RBMX PE=1 SV=3" 6 1984.7 - 1.82E+06 - - - -0.2451 - 1.179 0.068 - 111.4 1 2 0 -0.0002 8 0 0 0 2.21E+08 1.35E+08 - - - 0.0398 0.9518 221125_WJC_METTL3_EV_vs_WT_F03.07882.07882.2 4.7 14-Jul R.DAIAQAVR[166.11].G "sp|P29401|TKT_HUMAN,tr|A0A0B4J1R6|A0A0B4J1R6_HUMAN" 2 852.4693 7.57 25719 7882 2 852.470273 427.2419 Transketolase OS=Homo sapiens OX=9606 GN=TKT PE=1 SV=3 5.84 1985.8 - 2.01E+06 - - - 1.1578 - 1.199 0.081 - 156 7 2 0 0.001 8 0 0 0 5.94E+08 7.84E+07 - - - -0.1912 0.9995 221125_WJC_METTL3_EV_vs_WT_F03.07895.07895.2 0.739 20-Nov R.LLSEGADVNAK.H "sp|Q9H078|CLPB_HUMAN,tr|A0A2U3TZY2|A0A2U3TZY2_HUMAN,tr|H0YGM0|H0YGM0_HUMAN,tr|F5H392|F5H392_HUMAN,tr|A0A2R8Y6R5|A0A2R8Y6R5_HUMAN,tr|F5H7A5|F5H7A5_HUMAN" 6 1115.5823 0.85 25725 7895 2 1115.582992 558.7984 Caseinolytic peptidase B protein homolog OS=Homo sapiens OX=9606 GN=CLPB PE=1 SV=1 4.37 1987.4 - 390484 - - - 0.6624 - 2.016 0.304 - 295.5 1 2 0 0.0007 11 0 0 0 1.39E+07 1.64E+07 - - - 3.1828 0.9902 221125_WJC_METTL3_EV_vs_WT_F03.07907.07907.2 0.0913 16-May R.DVDGATLAR.L sp|Q16352|AINX_HUMAN 1 916.4614 1.7 25733 7907 2 916.461795 459.238 Alpha-internexin OS=Homo sapiens OX=9606 GN=INA PE=1 SV=2 4.21 1988.7 - 554465 - - - 0.4201 - 0.957 0.257 - 65.9 2 2 0 0.0004 9 0 0 0 1.34E+08 7.92E+07 - - - 0.6775 0.9992 221125_WJC_METTL3_EV_vs_WT_F03.07908.07908.2 0.00545 18-Aug R.LVTANTIDQK[136.11].L "sp|Q9NRZ9|HELLS_HUMAN,tr|Q9NW36|Q9NW36_HUMAN,tr|A0A087WSW7|A0A087WSW7_HUMAN,tr|A0A0B4J1V9|A0A0B4J1V9_HUMAN,tr|F6XU50|F6XU50_HUMAN" 5 1109.6172 0.49 25734 7908 2 1109.618783 555.8159 Lymphoid-specific helicase OS=Homo sapiens OX=9606 GN=HELLS PE=1 SV=1 5.84 1988.9 - 303017 - - - 1.4365 - 1.608 0.356 - 193 1 2 0 0.0016 10 0 0 0 6.30E+06 1.30E+07 - - - 2.9958 0.9976 221125_WJC_METTL3_EV_vs_WT_F03.07920.07920.2 0.0347 16-Jul R.DVDGATLAR[166.11].L sp|Q16352|AINX_HUMAN 1 926.4697 2.7 25738 7920 2 926.470689 464.2421 Alpha-internexin OS=Homo sapiens OX=9606 GN=INA PE=1 SV=2 4.21 1990.5 - 1.05E+06 - - - 1.0891 - 1.121 0.341 - 128.8 1 2 0 0.001 9 0 0 0 2.15E+08 7.96E+07 - - - 1.8898 0.9584 221125_WJC_METTL3_EV_vs_WT_F03.07923.07923.2 3.44 14-May R.GPPPSWGR.R sp|P84103|SRSF3_HUMAN 1 852.4242 0.17 25740 7923 2 852.424255 427.2194 Serine\arginine-rich splicing factor 3 OS=Homo sapiens OX=9606 GN=SRSF3 PE=1 SV=1 9.75 1990.8 - 2.33E+06 - - - 0.0223 - 0.966 0.101 - 108.6 1 2 0 0 8 0 0 0 8.73E+07 5.03E+08 - - - -0.3173 0.9718 221125_WJC_METTL3_EV_vs_WT_F03.07928.07928.2 0.115 12-Jun R.EHLLLAR.Q sp|P49411|EFTU_HUMAN 1 850.5025 1146.83 25743 7928 2 850.500971 426.2585 "Elongation factor Tu, mitochondrial OS=Homo sapiens OX=9606 GN=TUFM PE=1 SV=2" 6.85 1991.4 - 3.06E+06 - - - -1.7825 - 1.265 0.074 - 234.2 1 2 0 -0.0015 7 0 0 0 1.31E+08 1.14E+05 - - - 0.3319 0.9982 221125_WJC_METTL3_EV_vs_WT_F03.07929.07929.2 0.00582 16-Sep K.DVDAAYVSK.V sp|Q7Z794|K2C1B_HUMAN 1 966.4658 24.14 25744 7929 2 966.464609 484.2402 "Keratin, type II cytoskeletal 1b OS=Homo sapiens OX=9606 GN=KRT77 PE=1 SV=3" 4.21 1991.5 - 493909 - - - -1.2592 - 1.191 0.346 - 194.5 1 2 0 -0.0012 9 0 0 0 5.48E+07 2.27E+06 - - - 2.1019 0.9951 221125_WJC_METTL3_EV_vs_WT_F03.07930.07930.2 0.276 12-Jun R.DYVAVAR[166.11].G sp|P78527|PRKDC_HUMAN 1 802.4213 0.73 25745 7930 2 802.420885 402.2179 DNA-dependent protein kinase catalytic subunit OS=Homo sapiens OX=9606 GN=PRKDC PE=1 SV=3 5.84 1991.6 - 1.98E+06 - - - -0.4835 - 1.133 0.229 - 135.9 1 2 0 -0.0004 7 0 0 0 6.77E+07 9.28E+07 - - - 1.1279 0.9552 221125_WJC_METTL3_EV_vs_WT_F03.07931.07931.2 1.59 14-Jul R.LDPGTISR.G "sp|O15460|P4HA2_HUMAN,tr|E7ERI1|E7ERI1_HUMAN,tr|E7EPI9|E7EPI9_HUMAN,tr|E7ENX0|E7ENX0_HUMAN,tr|C9JX45|C9JX45_HUMAN,tr|A8MXE0|A8MXE0_HUMAN" 6 857.4607 1.18 25746 7931 2 857.458673 429.7376 Prolyl 4-hydroxylase subunit alpha-2 OS=Homo sapiens OX=9606 GN=P4HA2 PE=1 SV=1 5.84 1991.7 - 725030 - - - -2.3418 - 1.254 0.075 - 132.7 1 2 0 -0.002 8 0 0 0 5.70E+07 4.83E+07 - - - 0.2769 0.86 221125_WJC_METTL3_EV_vs_WT_F03.07933.07933.2 1.05 12-Jul L.LTLAEER[166.11].T "sp|Q8N1K5|THMS1_HUMAN,sp|P62701|RS4X_HUMAN,sp|Q8TD47|RS4Y2_HUMAN,tr|A0A0D9SFD2|A0A0D9SFD2_HUMAN" 4 840.4581 0.98 25747 7933 2 840.457565 421.2363 Protein THEMIS OS=Homo sapiens OX=9606 GN=THEMIS PE=1 SV=3 4.53 1991.9 - 7.36E+07 - - - -0.5794 - 1.547 0.158 - 218.7 1 1 0 -0.0005 7 0 0 0 3.19E+09 3.24E+09 - - - 1.5903 0.9994 221125_WJC_METTL3_EV_vs_WT_F03.07941.07941.2 0.00357 20-Sep R.AMVASGSELGK.K "sp|P54819|KAD2_HUMAN,tr|A0A5F9ZHP2|A0A5F9ZHP2_HUMAN,tr|G3V213|G3V213_HUMAN,tr|F8W1A4|F8W1A4_HUMAN,tr|F8VZG5|F8VZG5_HUMAN" 5 1048.5223 0.79 25753 7941 2 1048.523088 525.2684 "Adenylate kinase 2, mitochondrial OS=Homo sapiens OX=9606 GN=AK2 PE=1 SV=2" 6.05 1992.7 - 438653 - - - 0.7563 - 1.655 0.351 - 207.6 1 2 0 0.0008 11 0 0 0 1.93E+07 2.43E+07 - - - 2.9961 0.9985 221125_WJC_METTL3_EV_vs_WT_F03.07944.07944.2 0.146 16-Sep K.GPLATGGIK[136.11].K "sp|Q9Y2S6|TMA7_HUMAN,tr|A0A024R1R8|A0A024R1R8_HUMAN" 2 820.4898 0.46 25754 7944 2 820.490648 411.2522 Translation machinery-associated protein 7 OS=Homo sapiens OX=9606 GN=TMA7 PE=1 SV=1 8.75 1993.1 - 1.77E+06 - - - 1.0299 - 1.627 0.25 - 259.7 1 2 0 0.0008 9 0 0 0 1.39E+08 3.05E+08 - - - 2.2954 0.9668 221125_WJC_METTL3_EV_vs_WT_F03.07946.07946.2 2.17 12-Jul R.ALQVMEK.V "sp|Q92552|RT27_HUMAN,tr|G5EA06|G5EA06_HUMAN,tr|D6RH20|D6RH20_HUMAN" 3 817.4368 0.95 25756 7946 2 817.438111 409.7257 "28S ribosomal protein S27, mitochondrial OS=Homo sapiens OX=9606 GN=MRPS27 PE=1 SV=3" 6.05 1993.2 - 2.23E+06 - - - 1.6344 - 1.147 0.101 - 163.1 1 2 0 0.0013 7 0 0 0 1.13E+08 1.19E+08 - - - 0.2211 0.9944 221125_WJC_METTL3_EV_vs_WT_F03.07949.07949.2 9.40E-06 16-Dec R.PSVVYPSTK.F "sp|P42694|HELZ_HUMAN,tr|J3QS41|J3QS41_HUMAN" 2 976.5229 0.78 25758 7949 2 976.523123 489.2687 Probable helicase with zinc finger domain OS=Homo sapiens OX=9606 GN=HELZ PE=1 SV=2 9.01 1993.5 - 1.44E+06 - - - 0.1802 - 2.589 0.492 - 489.1 1 1 0 0.0002 9 0 0 0 7.52E+07 9.62E+07 - - - 5.4269 0.9869 221125_WJC_METTL3_EV_vs_WT_F03.07951.07951.2 0.635 14-Jul R.ILQQSVVK[136.11].T sp|Q9H2J4|PDCL3_HUMAN 1 921.5739 0.52 25759 7951 2 921.573402 461.7942 Phosducin-like protein 3 OS=Homo sapiens OX=9606 GN=PDCL3 PE=1 SV=1 8.75 1993.7 - 674578 - - - -0.5046 - 1.295 0.086 - 107.5 1 2 0 -0.0005 8 0 0 0 1.03E+07 1.98E+07 - - - 0.4557 0.9663 221125_WJC_METTL3_EV_vs_WT_F03.07956.07956.2 3.16 12-Jul K.QVIEYAR.Q "sp|P48556|PSMD8_HUMAN,tr|R4GMR5|R4GMR5_HUMAN" 2 877.4658 0.37 25762 7956 2 877.465341 439.7402 26S proteasome non-ATPase regulatory subunit 8 OS=Homo sapiens OX=9606 GN=PSMD8 PE=1 SV=2 6 1994.2 - 1.76E+06 - - - -0.4855 - 1.17 0.04 - 187.4 1 2 0 -0.0004 7 0 0 0 9.71E+07 2.65E+08 - - - -0.1662 0.9937 221125_WJC_METTL3_EV_vs_WT_F03.07958.07958.2 0.389 16-Jun K.GPLATGGIK.K "sp|Q9Y2S6|TMA7_HUMAN,tr|A0A024R1R8|A0A024R1R8_HUMAN" 2 812.4756 0.48 25764 7958 2 812.476216 407.2451 Translation machinery-associated protein 7 OS=Homo sapiens OX=9606 GN=TMA7 PE=1 SV=1 8.75 1994.3 - 1.39E+06 - - - 0.7545 - 1.342 0.176 - 73.6 2 2 0 0.0006 9 0 0 0 1.39E+08 2.91E+08 - - - 1.0573 0.996 221125_WJC_METTL3_EV_vs_WT_F03.07965.07965.2 0.165 12-Jul K.LGLQHLR[166.11].S "sp|P84085|ARF5_HUMAN,tr|C9J1Z8|C9J1Z8_HUMAN" 2 845.5111 1.17 25768 7965 2 845.509903 423.7628 ADP-ribosylation factor 5 OS=Homo sapiens OX=9606 GN=ARF5 PE=1 SV=2 9.76 1995.1 - 3.09E+06 - - - -1.4051 - 1.507 0.163 - 151.9 1 2 0 -0.0012 7 0 0 0 1.01E+08 8.65E+07 - - - 1.544 0.9953 221125_WJC_METTL3_EV_vs_WT_F03.07968.07968.2 0.00914 16-Jul R.ANGMELDGR[166.11].R "sp|P62995|TRA2B_HUMAN,sp|Q13595|TRA2A_HUMAN,tr|H7BXF3|H7BXF3_HUMAN" 3 971.437 0.01 25769 7968 2 971.434478 486.7258 Transformer-2 protein homolog beta OS=Homo sapiens OX=9606 GN=TRA2B PE=1 SV=1 4.37 1995.5 - 549046 - - - -2.5951 - 1.419 0.272 - 120.9 1 2 0 -0.0025 9 0 0 0 1.28E+05 9.01E+06 - - - 2.0616 0.9912 221125_WJC_METTL3_EV_vs_WT_F03.07973.07973.2 0.433 14-Jul R.TITELGEK[136.11].A sp|P36957|ODO2_HUMAN 1 897.4899 3.78 25772 7973 2 897.489762 449.7522 "Dihydrolipoyllysine-residue succinyltransferase component of 2-oxoglutarate dehydrogenase complex, mitochondrial OS=Homo sapiens OX=9606 GN=DLST PE=1 SV=4" 4.53 1996.2 - 1.51E+06 - - - -0.1125 - 1.203 0.149 - 115.2 1 2 0 -0.0001 8 0 0 0 3.12E+08 8.26E+07 - - - 0.6989 0.9993 221125_WJC_METTL3_EV_vs_WT_F03.07974.07974.2 1.23 14-Jul R.ALC[160.03]ADEYR.A "sp|O14654|IRS4_HUMAN,tr|A0A804CF45|A0A804CF45_HUMAN" 2 996.4335 1.35 25773 7974 2 996.433656 499.224 Insulin receptor substrate 4 OS=Homo sapiens OX=9606 GN=IRS4 PE=1 SV=1 4.37 1996.3 - 1.44E+06 - - - 0.1756 - 1.731 0.264 - 217.5 1 2 0 0.0002 8 0 0 0 3.08E+07 2.28E+07 - - - 2.6457 0.9915 221125_WJC_METTL3_EV_vs_WT_F03.07983.07983.2 2.95 14-Jul R.ALC[160.03]ADEYR[166.11].A "sp|O14654|IRS4_HUMAN,tr|A0A804CF45|A0A804CF45_HUMAN" 2 1006.4418 1.35 25779 7983 2 1006.440119 504.2282 Insulin receptor substrate 4 OS=Homo sapiens OX=9606 GN=IRS4 PE=1 SV=1 4.37 1997.2 - 1.11E+06 - - - -1.6216 - 1.181 0.209 - 92.8 1 2 0 -0.0016 8 0 0 0 3.08E+07 2.28E+07 - - - 1.0859 0.9912 221125_WJC_METTL3_EV_vs_WT_F03.07987.07987.2 4.34 12-Jun K.LTSLNVK.Y "sp|O95758|PTBP3_HUMAN,sp|P26599|PTBP1_HUMAN,sp|Q8WXD9|CSKI1_HUMAN,tr|A0A6Q8PEX4|A0A6Q8PEX4_HUMAN,tr|A0A0U1RRM4|A0A0U1RRM4_HUMAN,tr|A6NLN1|A6NLN1_HUMAN,tr|A0A087WU68|A0A087WU68_HUMAN,tr|A0A7I2V4H6|A0A7I2V4H6_HUMAN,tr|A0A7I2V621|A0A7I2V621_HUMAN,tr|K7EK45|K7EK45_HUMAN" 10 773.4647 1 25781 7987 2 773.464837 387.7396 Polypyrimidine tract-binding protein 3 OS=Homo sapiens OX=9606 GN=PTBP3 PE=1 SV=2 8.75 1997.7 - 1.60E+07 - - - 0.172 - 1.462 0.064 - 83.9 1 2 0 0.0001 7 0 0 0 1.80E+09 1.80E+09 - - - 0.7171 0.9533 221125_WJC_METTL3_EV_vs_WT_F03.07989.07989.2 8.99 12-Jun K.LTSLNVK[136.11].Y "sp|O95758|PTBP3_HUMAN,sp|P26599|PTBP1_HUMAN,sp|Q8WXD9|CSKI1_HUMAN,tr|A0A6Q8PEX4|A0A6Q8PEX4_HUMAN,tr|A0A0U1RRM4|A0A0U1RRM4_HUMAN,tr|A6NLN1|A6NLN1_HUMAN,tr|A0A087WU68|A0A087WU68_HUMAN,tr|A0A7I2V4H6|A0A7I2V4H6_HUMAN,tr|A0A7I2V621|A0A7I2V621_HUMAN,tr|K7EK45|K7EK45_HUMAN" 10 781.4789 1 25783 7989 2 781.478005 391.7467 Polypyrimidine tract-binding protein 3 OS=Homo sapiens OX=9606 GN=PTBP3 PE=1 SV=2 8.75 1997.8 - 2.04E+07 - - - -1.1504 - 1.12 0.049 - 88.9 1 2 0 -0.0009 7 0 0 0 1.80E+09 1.80E+09 - - - -0.2383 0.9992 221125_WJC_METTL3_EV_vs_WT_F03.07991.07991.2 1.00E-05 20-Aug R.LVSSDPEINTK.K sp|Q9Y266|NUDC_HUMAN 1 1201.619 1.94 25785 7991 2 1201.622206 601.8168 Nuclear migration protein nudC OS=Homo sapiens OX=9606 GN=NUDC PE=1 SV=1 4.37 1998.1 - 220033 - - - 2.6406 - 1.7 0.462 - 139.9 1 2 0 0.0032 11 0 0 0 6.36E+06 3.27E+06 - - - 3.8878 0.8704 221125_WJC_METTL3_EV_vs_WT_F03.07994.07994.2 0.546 12-Jul L.LTLAEER.T "sp|Q8N1K5|THMS1_HUMAN,sp|P62701|RS4X_HUMAN,sp|Q8TD47|RS4Y2_HUMAN,tr|A0A0D9SFD2|A0A0D9SFD2_HUMAN" 4 830.4498 0.98 25786 7994 2 830.449754 416.2322 Protein THEMIS OS=Homo sapiens OX=9606 GN=THEMIS PE=1 SV=3 4.53 1998.5 - 5.38E+07 - - - -0.0337 - 1.548 0.162 - 217.9 1 1 0 0 7 0 0 0 3.18E+09 3.23E+09 - - - 1.6221 0.9915 221125_WJC_METTL3_EV_vs_WT_F03.08000.08000.2 0.000292 16-Aug Y.GTLTDDEMR[166.11].R sp|Q86U44|MTA70_HUMAN 1 1046.4578 0.02 25790 8000 2 1046.457861 524.2362 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 4.03 1999 - 2.41E+06 - - - 0.064 - 1.934 0.492 - 213.1 1 1 0 0.0001 9 0 0 0 2.63E+07 1.21E+09 - - - 4.5831 0.9926 221125_WJC_METTL3_EV_vs_WT_F03.08001.08001.2 1.64 14-Aug R.ELSEISER[166.11].L "sp|Q9BWU0|NADAP_HUMAN,tr|A0A087X0M4|A0A087X0M4_HUMAN" 2 971.4799 0.94 25791 8001 2 971.480783 486.7472 Kanadaptin OS=Homo sapiens OX=9606 GN=SLC4A1AP PE=1 SV=1 4.25 1999.1 - 496612 - - - 0.8986 - 1.303 0.155 - 210.7 1 2 0 0.0009 8 0 0 0 9.93E+06 1.06E+07 - - - 0.9838 0.9993 221125_WJC_METTL3_EV_vs_WT_F03.08004.08004.2 0.0103 16-Aug R.VPDVQDGVR.A "sp|Q15149|PLEC_HUMAN,tr|E9PMV1|E9PMV1_HUMAN,tr|H0YDN1|H0YDN1_HUMAN" 3 983.5036 2.06 25792 8004 2 983.504292 492.7591 Plectin OS=Homo sapiens OX=9606 GN=PLEC PE=1 SV=3 4.21 1999.5 - 869887 - - - 0.6945 - 1.54 0.352 - 212 1 2 0 0.0007 9 0 0 0 4.30E+07 2.08E+07 - - - 2.8898 0.9977 221125_WJC_METTL3_EV_vs_WT_F03.08005.08005.2 0.111 14-Aug R.QLSDIEER.H "sp|P07197|NFM_HUMAN,tr|E7ESP9|E7ESP9_HUMAN,tr|E7EMV2|E7EMV2_HUMAN" 3 988.4825 3.4 25793 8005 2 988.482282 495.2485 Neurofilament medium polypeptide OS=Homo sapiens OX=9606 GN=NEFM PE=1 SV=3 4.14 1999.6 - 722354 - - - -0.26 - 1.548 0.178 - 274.3 1 2 0 -0.0003 8 0 0 0 7.82E+07 2.30E+07 - - - 1.6735 0.9978 221125_WJC_METTL3_EV_vs_WT_F03.08006.08006.2 0.013 18-Jul K.VLSTSTGLTK[136.11].T "sp|Q5T8P6|RBM26_HUMAN,tr|A0A087X0H9|A0A087X0H9_HUMAN" 2 1013.5848 1.27 25794 8006 2 1013.584949 507.7997 RNA-binding protein 26 OS=Homo sapiens OX=9606 GN=RBM26 PE=1 SV=3 8.72 1999.7 - 761016 - - - 0.1214 - 1.438 0.225 - 81.9 1 2 0 0.0001 10 0 0 0 1.99E+07 1.57E+07 - - - 1.7168 0.9954 221125_WJC_METTL3_EV_vs_WT_F03.08008.08008.2 0.0177 16-Jul R.VGLEPPPGK.R "sp|Q9BSD7|NTPCR_HUMAN,tr|Q5TDF0|Q5TDF0_HUMAN" 2 892.5018 1.27 25795 8008 2 892.503907 447.2582 Cancer-related nucleoside-triphosphatase OS=Homo sapiens OX=9606 GN=NTPCR PE=1 SV=1 5.97 1999.9 - 5.16E+06 - - - 2.3406 - 1.41 0.262 - 157.1 1 2 0 0.0021 9 0 0 0 9.07E+08 7.17E+08 - - - 1.9695 0.9988 221125_WJC_METTL3_EV_vs_WT_F03.08011.08011.2 0.0175 14-Jul K.VNSMVAYK.L sp|Q13257|MD2L1_HUMAN 1 910.4582 0.31 25797 8011 2 910.4579 456.2364 Mitotic spindle assembly checkpoint protein MAD2A OS=Homo sapiens OX=9606 GN=MAD2L1 PE=1 SV=1 8.56 2000.2 - 2.37E+06 - - - -0.3723 - 1.375 0.297 - 133.5 1 2 0 -0.0003 8 0 0 0 1.11E+08 3.59E+08 - - - 2.195 0.9995 221125_WJC_METTL3_EV_vs_WT_F03.08013.08013.2 0.00288 22-Dec R.LEGNTVGVEAAR[166.11].V "sp|P46060|RAGP1_HUMAN,tr|B0QYT4|B0QYT4_HUMAN,tr|B0QYT5|B0QYT5_HUMAN" 3 1224.6338 1.15 25799 8013 2 1224.635703 613.3242 Ran GTPase-activating protein 1 OS=Homo sapiens OX=9606 GN=RANGAP1 PE=1 SV=1 4.53 2000.5 - 352440 - - - 1.5662 - 2.375 0.314 - 284.9 1 2 0 0.0019 12 0 0 0 7.63E+07 6.61E+07 - - - 3.6356 0.9995 221125_WJC_METTL3_EV_vs_WT_F03.08019.08019.2 0.0971 14-Sep R.VQVQVVER[166.11].A "sp|O75955|FLOT1_HUMAN,tr|A0A140T9W4|A0A140T9W4_HUMAN,tr|A2AB09|A2AB09_HUMAN,tr|A0A140T9R1|A0A140T9R1_HUMAN,tr|A0A140T9X0|A0A140T9X0_HUMAN,tr|A0A140T907|A0A140T907_HUMAN" 6 965.5534 3.13 25803 8019 2 965.553095 483.784 Flotillin-1 OS=Homo sapiens OX=9606 GN=FLOT1 PE=1 SV=3 5.97 2001.1 - 1.03E+06 - - - -0.2641 - 1.898 0.283 - 368.2 1 2 0 -0.0003 8 0 0 0 1.72E+08 5.49E+07 - - - 3.0638 0.9823 221125_WJC_METTL3_EV_vs_WT_F03.08021.08021.2 0.0353 22-Jun K.LITAADTTAEQR[166.11].R "sp|Q9NPF5|DMAP1_HUMAN,tr|Q5TG40|Q5TG40_HUMAN" 2 1298.6706 0.001 25805 8021 2 1298.667135 650.3426 DNA methyltransferase 1-associated protein 1 OS=Homo sapiens OX=9606 GN=DMAP1 PE=1 SV=1 4.37 2001.3 - 136423 - - - -2.6404 - 1.45 0.161 - 98.9 2 2 0 -0.0034 12 0 0 0 0.00E+00 2.76E+07 - - - 1.0722 0.9997 221125_WJC_METTL3_EV_vs_WT_F03.08026.08026.2 0.00081 22-Dec R.LEGNTVGVEAAR.V "sp|P46060|RAGP1_HUMAN,tr|B0QYT4|B0QYT4_HUMAN,tr|B0QYT5|B0QYT5_HUMAN" 3 1214.6255 1.12 25808 8026 2 1214.624852 608.32 Ran GTPase-activating protein 1 OS=Homo sapiens OX=9606 GN=RANGAP1 PE=1 SV=1 4.53 2001.9 - 751047 - - - -0.5458 - 2.362 0.323 - 527.4 1 2 0 -0.0007 12 0 0 0 7.39E+07 6.61E+07 - - - 3.688 0.8319 221125_WJC_METTL3_EV_vs_WT_F03.08029.08029.2 1.46 16-Jun K.LQELSAEER.Q "sp|Q9NTK5|OLA1_HUMAN,tr|J3KQ32|J3KQ32_HUMAN" 2 1073.5353 0.7 25811 8029 2 1073.539982 537.7749 Obg-like ATPase 1 OS=Homo sapiens OX=9606 GN=OLA1 PE=1 SV=2 4.25 2002.2 - 303226 - - - 4.3585 - 1.241 0.116 - 116.6 3 2 0 0.0047 9 0 0 0 7.03E+06 1.00E+07 - - - 0.3078 0.9984 221125_WJC_METTL3_EV_vs_WT_F03.08036.08036.2 0.0251 14-Jul K.AIETFSGK.V sp|Q9NZI8|IF2B1_HUMAN 1 851.4389 0.93 25814 8036 2 851.43903 426.7267 Insulin-like growth factor 2 mRNA-binding protein 1 OS=Homo sapiens OX=9606 GN=IGF2BP1 PE=1 SV=2 6.05 2003.1 - 8.19E+06 - - - 0.1726 - 1.26 0.302 - 170.5 1 2 0 0.0001 8 0 0 0 1.41E+09 1.51E+09 - - - 1.9685 0.9817 221125_WJC_METTL3_EV_vs_WT_F03.08037.08037.2 0.00634 16-Aug Y.GTLTDDEMR.R sp|Q86U44|MTA70_HUMAN 1 1036.4495 0.02 25815 8037 2 1036.447689 519.232 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 4.03 2003.2 - 427800 - - - -1.7705 - 1.748 0.497 - 223.8 1 1 0 -0.0018 9 0 0 0 2.51E+07 1.20E+09 - - - 4.327 0.9984 221125_WJC_METTL3_EV_vs_WT_F03.08041.08041.2 0.00402 16-Jul K.LITEDVQGK[136.11].N "sp|P61247|RS3A_HUMAN,tr|H0Y8L7|H0Y8L7_HUMAN,tr|D6RED7|D6RED7_HUMAN,tr|D6RGE0|D6RGE0_HUMAN,tr|D6RAS7|D6RAS7_HUMAN,tr|D6RB09|D6RB09_HUMAN,tr|E9PFI5|E9PFI5_HUMAN,tr|D6RAT0|D6RAT0_HUMAN,tr|D6RG13|D6RG13_HUMAN" 9 1009.5535 1.01 25817 8041 2 1009.553209 505.784 40S ribosomal protein S3a OS=Homo sapiens OX=9606 GN=RPS3A PE=1 SV=2 4.37 2003.7 - 926025 - - - -0.314 - 1.304 0.291 - 104.9 1 2 0 -0.0003 9 0 0 0 1.59E+09 1.58E+09 - - - 1.9581 0.9992 221125_WJC_METTL3_EV_vs_WT_F03.08044.08044.2 0.472 14-Sep R.VQVQVVER.A "sp|O75955|FLOT1_HUMAN,tr|A0A140T9W4|A0A140T9W4_HUMAN,tr|A2AB09|A2AB09_HUMAN,tr|A0A140T9R1|A0A140T9R1_HUMAN,tr|A0A140T9X0|A0A140T9X0_HUMAN,tr|A0A140T907|A0A140T907_HUMAN" 6 955.5451 3.54 25818 8044 2 955.545643 478.7798 Flotillin-1 OS=Homo sapiens OX=9606 GN=FLOT1 PE=1 SV=3 5.97 2004.1 - 4.32E+06 - - - 0.5892 - 1.913 0.229 - 333.3 1 2 0 0.0006 8 0 0 0 1.95E+08 5.51E+07 - - - 2.6886 0.9996 221125_WJC_METTL3_EV_vs_WT_F03.08045.08045.2 0.00034 18-Aug R.YVEVSPATER[166.11].Q sp|Q9NTZ6|RBM12_HUMAN 1 1159.5749 1.26 25819 8045 2 1159.574461 580.7947 RNA-binding protein 12 OS=Homo sapiens OX=9606 GN=RBM12 PE=1 SV=1 4.53 2004.2 - 911013 - - - -0.3553 - 1.692 0.384 - 209.3 1 2 0 -0.0004 10 0 0 0 1.07E+08 8.50E+07 - - - 3.3451 0.9958 221125_WJC_METTL3_EV_vs_WT_F03.08049.08049.2 0.222 12-Jun R.QLSESFK.S sp|Q08945|SSRP1_HUMAN 1 837.4232 0.74 25821 8049 2 837.423239 419.7189 FACT complex subunit SSRP1 OS=Homo sapiens OX=9606 GN=SSRP1 PE=1 SV=1 6 2004.6 - 2.48E+06 - - - 0.0072 - 1.319 0.178 - 146.9 1 2 0 0 7 0 0 0 9.05E+07 1.22E+08 - - - 1.233 0.9986 221125_WJC_METTL3_EV_vs_WT_F03.08050.08050.2 0.168 16-Jul K.EIAENALGK.H sp|P31942|HNRH3_HUMAN 1 943.4975 1.89 25822 8050 2 943.497405 472.756 Heterogeneous nuclear ribonucleoprotein H3 OS=Homo sapiens OX=9606 GN=HNRNPH3 PE=1 SV=2 4.53 2004.7 - 6.46E+06 - - - -0.0594 - 1.426 0.274 - 186 1 2 0 -0.0001 9 0 0 0 7.50E+08 3.98E+08 - - - 2.0914 0.9992 221125_WJC_METTL3_EV_vs_WT_F03.08051.08051.2 0.0146 16-Oct K.LITEDVQGK.N "sp|P61247|RS3A_HUMAN,tr|H0Y8L7|H0Y8L7_HUMAN,tr|D6RED7|D6RED7_HUMAN,tr|D6RGE0|D6RGE0_HUMAN,tr|D6RAS7|D6RAS7_HUMAN,tr|D6RB09|D6RB09_HUMAN,tr|E9PFI5|E9PFI5_HUMAN,tr|D6RAT0|D6RAT0_HUMAN,tr|D6RG13|D6RG13_HUMAN" 9 1001.5393 1.01 25823 8051 2 1001.538909 501.7769 40S ribosomal protein S3a OS=Homo sapiens OX=9606 GN=RPS3A PE=1 SV=2 4.37 2004.7 - 2.42E+06 - - - -0.4164 - 1.861 0.242 - 249.8 1 2 0 -0.0004 9 0 0 0 1.59E+09 1.58E+09 - - - 2.6252 0.999 221125_WJC_METTL3_EV_vs_WT_F03.08059.08059.2 0.258 16-Aug K.EIAENALGK[136.11].H sp|P31942|HNRH3_HUMAN 1 951.5117 1.87 25828 8059 2 951.510517 476.7631 Heterogeneous nuclear ribonucleoprotein H3 OS=Homo sapiens OX=9606 GN=HNRNPH3 PE=1 SV=2 4.53 2005.8 - 5.06E+06 - - - -1.2023 - 1.758 0.268 - 267.6 1 2 0 -0.0011 9 0 0 0 7.52E+08 4.01E+08 - - - 2.6523 0.9967 221125_WJC_METTL3_EV_vs_WT_F03.08060.08060.2 0.0366 16-Sep K.LADQPLTPK.S "sp|Q96S82|UBL7_HUMAN,tr|H3BV23|H3BV23_HUMAN,tr|H3BUV9|H3BUV9_HUMAN" 3 981.5495 2.61 25829 8060 2 981.547626 491.782 Ubiquitin-like protein 7 OS=Homo sapiens OX=9606 GN=UBL7 PE=1 SV=2 5.84 2005.9 - 683026 - - - -1.9052 - 1.851 0.155 - 211.1 1 2 0 -0.0019 9 0 0 0 6.96E+07 2.67E+07 - - - 1.9666 0.9991 221125_WJC_METTL3_EV_vs_WT_F03.08067.08067.2 0.00232 22-Jun R.QAASSLQQASLK[136.11].L "sp|P38646|GRP75_HUMAN,tr|A0A7I2V2S7|A0A7I2V2S7_HUMAN,tr|A0A7I2V2G2|A0A7I2V2G2_HUMAN,tr|A0A7I2V3F7|A0A7I2V3F7_HUMAN,tr|A0A7I2YQB2|A0A7I2YQB2_HUMAN,tr|D6RCD7|D6RCD7_HUMAN" 6 1238.671 0.74 25834 8067 2 1238.668761 620.3428 "Stress-70 protein, mitochondrial OS=Homo sapiens OX=9606 GN=HSPA9 PE=1 SV=2" 8.75 2006.6 - 81944.3 - - - -1.8197 - 1.534 0.389 - 62.5 1 2 0 -0.0023 12 0 0 0 1.13E+06 1.52E+06 - - - 3.0393 0.9951 221125_WJC_METTL3_EV_vs_WT_F03.08071.08071.2 0.0647 12-Jul R.SVYIDAR[166.11].D sp|Q8WU90|ZC3HF_HUMAN 1 832.4318 0.55 25836 8071 2 832.429627 417.2232 Zinc finger CCCH domain-containing protein 15 OS=Homo sapiens OX=9606 GN=ZC3H15 PE=1 SV=1 5.55 2007 - 1.94E+06 - - - -2.6561 - 1.3 0.298 - 216 1 2 0 -0.0022 7 0 0 0 3.57E+07 6.48E+07 - - - 2.0726 0.9963 221125_WJC_METTL3_EV_vs_WT_F03.08072.08072.2 0.0839 12-Jul K.GLQDSIR.K sp|P15924|DESP_HUMAN 1 787.4188 10.61 25837 8072 2 787.418879 394.7167 Desmoplakin OS=Homo sapiens OX=9606 GN=DSP PE=1 SV=3 5.84 2007.1 - 663997 - - - 0.0787 - 1.316 0.19 - 152.5 1 2 0 0.0001 7 0 0 0 4.62E+08 4.36E+07 - - - 1.3144 0.9989 221125_WJC_METTL3_EV_vs_WT_F03.08079.08079.2 0.00468 14-Aug R.TSVETALR[166.11].A "sp|P47755|CAZA2_HUMAN,tr|C9JUG7|C9JUG7_HUMAN,tr|A0A0D9SET8|A0A0D9SET8_HUMAN,tr|F8W9N7|F8W9N7_HUMAN" 4 885.4795 0.92 25841 8079 2 885.478847 443.747 F-actin-capping protein subunit alpha-2 OS=Homo sapiens OX=9606 GN=CAPZA2 PE=1 SV=3 5.66 2008 - 1.86E+06 - - - -0.7555 - 1.447 0.296 - 246.7 1 2 0 -0.0007 8 0 0 0 6.11E+07 6.62E+07 - - - 2.3414 0.9697 221125_WJC_METTL3_EV_vs_WT_F03.08087.08087.2 1.51 12-May R.FSGVPDR.F "sp|A0A075B6R9|KVD24_HUMAN,sp|A0A0C4DH68|KV224_HUMAN,sp|A2NJV5|KV229_HUMAN,sp|A0A075B6S2|KVD29_HUMAN,sp|A0A0A0MRZ7|KVD26_HUMAN" 5 776.3817 601.15 25845 8087 2 776.381516 389.1981 Probable non-functional immunoglobulin kappa variable 2D-24 OS=Homo sapiens OX=9606 GN=IGKV2D-24 PE=1 SV=1 5.84 2008.9 - 1.13E+07 - - - -0.2409 - 1.054 0.11 - 76.4 2 2 0 -0.0002 7 0 0 0 3.39E+08 5.63E+05 - - - -0.1144 0.9921 221125_WJC_METTL3_EV_vs_WT_F03.08088.08088.2 3.34 12-Jun R.TIELDGK[136.11].R "sp|P61006|RAB8A_HUMAN,sp|Q9H0U4|RAB1B_HUMAN,sp|P62820|RAB1A_HUMAN,sp|Q92930|RAB8B_HUMAN,sp|Q92928|RAB1C_HUMAN,tr|H0YMN7|H0YMN7_HUMAN,tr|H0YNE9|H0YNE9_HUMAN,tr|E9PLD0|E9PLD0_HUMAN" 8 782.4265 1.14 25846 8088 2 782.426228 392.2205 Ras-related protein Rab-8A OS=Homo sapiens OX=9606 GN=RAB8A PE=1 SV=1 4.37 2008.9 - 1.03E+07 - - - -0.3911 - 1.134 0.182 - 121.9 1 2 0 -0.0003 7 0 0 0 8.69E+08 7.61E+08 - - - 0.7836 0.9998 221125_WJC_METTL3_EV_vs_WT_F03.08089.08089.2 3.75E-05 16-Oct K.VYEATIEEK.T "sp|P42694|HELZ_HUMAN,tr|J3QS41|J3QS41_HUMAN,tr|A0A075B6R3|A0A075B6R3_HUMAN" 3 1080.5339 2.42 25847 8089 2 1080.53346 541.2742 Probable helicase with zinc finger domain OS=Homo sapiens OX=9606 GN=HELZ PE=1 SV=2 4.25 2009.1 - 660989 - - - -0.4128 - 1.678 0.471 - 308.4 1 2 0 -0.0004 9 0 0 0 1.64E+08 6.79E+07 - - - 4.0171 0.9795 221125_WJC_METTL3_EV_vs_WT_F03.08092.08092.2 7.02 12-Jul R.TIELDGK.R "sp|P61006|RAB8A_HUMAN,sp|Q9H0U4|RAB1B_HUMAN,sp|P62820|RAB1A_HUMAN,sp|Q92930|RAB8B_HUMAN,sp|Q92928|RAB1C_HUMAN,tr|H0YMN7|H0YMN7_HUMAN,tr|H0YNE9|H0YNE9_HUMAN,tr|E9PLD0|E9PLD0_HUMAN" 8 774.4123 1.13 25848 8092 2 774.412199 388.2134 Ras-related protein Rab-8A OS=Homo sapiens OX=9606 GN=RAB8A PE=1 SV=1 4.37 2009.5 - 1.20E+07 - - - -0.1743 - 1.104 0.106 - 177.9 1 2 0 -0.0001 7 0 0 0 8.58E+08 7.58E+08 - - - 0.1374 0.9586 221125_WJC_METTL3_EV_vs_WT_F03.08094.08094.2 0.584 16-Jul R.TVPVGGVVK[136.11].S sp|Q14137|BOP1_HUMAN 1 862.5368 1.16 25850 8094 2 862.535294 432.2757 Ribosome biogenesis protein BOP1 OS=Homo sapiens OX=9606 GN=BOP1 PE=1 SV=2 8.41 2009.6 - 4.34E+06 - - - -1.6915 - 1.003 0.152 - 96.9 2 2 0 -0.0015 9 0 0 0 6.65E+07 5.71E+07 - - - 0.0374 0.9997 221125_WJC_METTL3_EV_vs_WT_F03.08096.08096.2 8.15E-05 20-Nov R.YPGSPGSYAAR.Q "sp|Q16769|QPCT_HUMAN,tr|A0A3B3IUD5|A0A3B3IUD5_HUMAN" 2 1124.5251 1.6 25852 8096 2 1124.526219 563.2698 Glutaminyl-peptide cyclotransferase OS=Homo sapiens OX=9606 GN=QPCT PE=1 SV=1 8.59 2009.8 - 851693 - - - 1.0191 - 1.896 0.445 - 447.2 1 2 0 0.0011 11 0 0 0 5.55E+07 3.47E+07 - - - 4.0581 0.9995 221125_WJC_METTL3_EV_vs_WT_F03.08100.08100.2 0.00301 16-Sep R.QLGSAALAR.H "sp|Q8N6H7|ARFG2_HUMAN,tr|H0YDX1|H0YDX1_HUMAN,tr|E9PIY6|E9PIY6_HUMAN,tr|E9PJT7|E9PJT7_HUMAN,tr|E9PN48|E9PN48_HUMAN,tr|E9PK28|E9PK28_HUMAN,tr|H0YF45|H0YF45_HUMAN,tr|G5E9L0|G5E9L0_HUMAN" 8 885.5032 1.03 25854 8100 2 885.502923 443.7589 ADP-ribosylation factor GTPase-activating protein 2 OS=Homo sapiens OX=9606 GN=ARFGAP2 PE=1 SV=1 9.75 2010.2 - 1.88E+06 - - - -0.3298 - 1.65 0.337 - 280.7 1 2 0 -0.0003 9 0 0 0 3.91E+08 3.78E+08 - - - 2.9788 0.7653 221125_WJC_METTL3_EV_vs_WT_F03.08105.08105.2 0.399 16-Apr R.IQPDYPAER[166.11].S "sp|Q9H0E3|SP130_HUMAN,tr|A0A2R8YDB8|A0A2R8YDB8_HUMAN,tr|H7BXF5|H7BXF5_HUMAN" 3 1097.5381 1.36 25856 8105 2 1097.536565 549.7763 Histone deacetylase complex subunit SAP130 OS=Homo sapiens OX=9606 GN=SAP130 PE=1 SV=1 4.37 2010.8 - 408341 - - - -1.3931 - 1.02 0.002 - 46.6 8 2 0 -0.0015 9 0 0 0 1.94E+07 1.42E+07 - - - -1.2908 0.9986 221125_WJC_METTL3_EV_vs_WT_F03.08107.08107.2 0.0127 12-Jul R.SVYIDAR.D sp|Q8WU90|ZC3HF_HUMAN 1 822.4236 0.54 25857 8107 2 822.423957 412.2191 Zinc finger CCCH domain-containing protein 15 OS=Homo sapiens OX=9606 GN=ZC3H15 PE=1 SV=1 5.55 2011 - 474075 - - - 0.473 - 1.284 0.317 - 174.4 1 2 0 0.0004 7 0 0 0 3.98E+07 7.40E+07 - - - 2.1743 0.987 221125_WJC_METTL3_EV_vs_WT_F03.08110.08110.2 1.02 16-Aug R.QEVAAAALR[166.11].G "sp|Q96NU1|SAM11_HUMAN,tr|A0A087WYW1|A0A087WYW1_HUMAN,tr|A0A087WX24|A0A087WX24_HUMAN,tr|A0A087X1J5|A0A087X1J5_HUMAN,tr|H7BY14|H7BY14_HUMAN,tr|H7C3J6|H7C3J6_HUMAN,tr|A0A087WYU3|A0A087WYU3_HUMAN,tr|A0A087WU74|A0A087WU74_HUMAN" 8 937.5221 0.51 25858 8110 2 937.519362 469.7683 Sterile alpha motif domain-containing protein 11 OS=Homo sapiens OX=9606 GN=SAMD11 PE=1 SV=3 6 2011.4 - 309243 - - - -2.8671 - 1.438 0.18 - 177 1 2 0 -0.0027 9 0 0 0 4.44E+06 8.66E+06 - - - 1.4205 0.9988 221125_WJC_METTL3_EV_vs_WT_F03.08112.08112.2 1.05 16-Aug R.LEALDANSR.K "sp|P09496|CLCA_HUMAN,tr|F8WF69|F8WF69_HUMAN" 2 987.4985 0.65 25859 8112 2 987.498749 494.7565 Clathrin light chain A OS=Homo sapiens OX=9606 GN=CLTA PE=1 SV=1 4.37 2011.6 - 2.51E+06 - - - 0.2289 - 1.818 0.195 - 223.2 1 2 0 0.0002 9 0 0 0 1.55E+08 2.39E+08 - - - 2.2105 0.8017 221125_WJC_METTL3_EV_vs_WT_F03.08114.08114.2 0.101 12-Jun K.LVELTQK[136.11].P "sp|Q9NP80|PLPL8_HUMAN,sp|P42704|LPPRC_HUMAN,tr|A0A804HI14|A0A804HI14_HUMAN,tr|A0A804HL40|A0A804HL40_HUMAN,tr|A0A804HKJ0|A0A804HKJ0_HUMAN,tr|A0A804HKR3|A0A804HKR3_HUMAN,tr|A0A804HIN4|A0A804HIN4_HUMAN,tr|A0A804HJG8|A0A804HJG8_HUMAN,tr|A0A804HLG8|A0A804HLG8_HUMAN,tr|A0A804HHY9|A0A804HHY9_HUMAN,tr|A0A804HI44|A0A804HI44_HUMAN,tr|A0A804HI40|A0A804HI40_HUMAN,tr|A0A804HJZ1|A0A804HJZ1_HUMAN,tr|A0A804HIQ7|A0A804HIQ7_HUMAN,tr|A0A804HK30|A0A804HK30_HUMAN,tr|A0A0C4DG51|A0A0C4DG51_HUMAN,tr|A0A804HKI2|A0A804HKI2_HUMAN,tr|A0A804HJI0|A0A804HJI0_HUMAN,tr|A0A804HIG4|A0A804HIG4_HUMAN" 19 837.5051 0.74 25861 8114 2 837.505727 419.7598 Calcium-independent phospholipase A2-gamma OS=Homo sapiens OX=9606 GN=PNPLA8 PE=1 SV=1 6 2011.7 - 2.35E+06 - - - 0.726 - 1.152 0.254 - 88.2 1 1 0 0.0006 7 0 0 0 1.09E+08 1.46E+08 - - - 1.3652 0.9946 221125_WJC_METTL3_EV_vs_WT_F03.08117.08117.2 0.0532 12-Jul K.HAIPIIK[136.11].E "sp|O00571|DDX3X_HUMAN,sp|O15523|DDX3Y_HUMAN,tr|A0A2R8YFR4|A0A2R8YFR4_HUMAN,tr|A0A2R8YCW1|A0A2R8YCW1_HUMAN,tr|A0A2R8YDH3|A0A2R8YDH3_HUMAN,tr|A0A2R8YDT5|A0A2R8YDT5_HUMAN,tr|A0A2R8Y645|A0A2R8Y645_HUMAN,tr|A0A2R8YF78|A0A2R8YF78_HUMAN,tr|C9J8G5|C9J8G5_HUMAN,tr|A0A2R8Y4D2|A0A2R8Y4D2_HUMAN,tr|A0A0D9SFB3|A0A0D9SFB3_HUMAN,tr|A0A2R8YFS5|A0A2R8YFS5_HUMAN,tr|A0A0D9SF53|A0A0D9SF53_HUMAN,tr|C9J081|C9J081_HUMAN,tr|A0A2R8Y5G6|A0A2R8Y5G6_HUMAN,tr|A0A2R8Y7T2|A0A2R8Y7T2_HUMAN,tr|A0A0D9SG12|A0A0D9SG12_HUMAN,tr|F6S8Q4|F6S8Q4_HUMAN,tr|A0A2U3TZJ9|A0A2U3TZJ9_HUMAN,tr|A0A2R8Y4A4|A0A2R8Y4A4_HUMAN" 20 798.5207 1.18 25862 8117 2 798.51988 400.2676 ATP-dependent RNA helicase DDX3X OS=Homo sapiens OX=9606 GN=DDX3X PE=1 SV=3 8.76 2012.1 - 1.26E+06 - - - -1.0382 - 1.57 0.097 - 153.8 1 2 0 -0.0008 7 0 0 0 5.56E+08 4.72E+08 - - - 1.1864 0.9998 221125_WJC_METTL3_EV_vs_WT_F03.08121.08121.2 1.23E-06 20-Dec K.C[160.03]VVVGDGAVGK[136.11].T "sp|P17081|RHOQ_HUMAN,sp|P63000|RAC1_HUMAN,sp|P84095|RHOG_HUMAN,sp|Q9H4E5|RHOJ_HUMAN,sp|P60953|CDC42_HUMAN,sp|P60763|RAC3_HUMAN,sp|P15153|RAC2_HUMAN,tr|G3V4H1|G3V4H1_HUMAN,tr|A0A3B3IRV0|A0A3B3IRV0_HUMAN,tr|B1AH79|B1AH79_HUMAN,tr|B1AH78|B1AH78_HUMAN,tr|A0A494C1M1|A0A494C1M1_HUMAN,tr|F8WET9|F8WET9_HUMAN,tr|A0A494BZX6|A0A494BZX6_HUMAN,tr|A0A590UJK8|A0A590UJK8_HUMAN,tr|G3V476|G3V476_HUMAN,tr|Q5JYX0|Q5JYX0_HUMAN" 17 1067.5525 0.9 25864 8121 2 1067.552821 534.7835 Rho-related GTP-binding protein RhoQ OS=Homo sapiens OX=9606 GN=RHOQ PE=1 SV=2 5.83 2012.6 - 1.59E+06 - - - 0.3194 - 2.055 0.409 - 375.6 1 2 0 0.0003 11 0 0 0 2.00E+08 2.23E+08 - - - 4.0103 0.7791 221125_WJC_METTL3_EV_vs_WT_F03.08125.08125.2 0.35 14-Jun L.DPESVELK[136.11].W "sp|P39748|FEN1_HUMAN,tr|I3L3E9|I3L3E9_HUMAN" 2 923.4691 0.6 25866 8125 2 923.468785 462.7418 Flap endonuclease 1 OS=Homo sapiens OX=9606 GN=FEN1 PE=1 SV=1 4.14 2013.1 - 2.62E+06 - - - -0.3703 - 1.271 0.188 - 147.2 1 1 0 -0.0003 8 0 0 0 5.32E+08 8.86E+08 - - - 1.1527 0.9993 221125_WJC_METTL3_EV_vs_WT_F03.08129.08129.2 0.0073 14-Sep R.VIEC[160.03]DVVK[136.11].D "sp|Q96PK6|RBM14_HUMAN,tr|B8ZZ74|B8ZZ74_HUMAN,tr|F8WDX3|F8WDX3_HUMAN,tr|A0A0A0MSL8|A0A0A0MSL8_HUMAN,tr|A0A0A6YYI9|A0A0A6YYI9_HUMAN" 5 968.5092 1.62 25869 8129 2 968.509684 485.2619 RNA-binding protein 14 OS=Homo sapiens OX=9606 GN=RBM14 PE=1 SV=2 4.37 2013.4 - 2.98E+06 - - - 0.4812 - 1.572 0.324 - 239.3 1 2 0 0.0005 8 0 0 0 2.85E+09 1.76E+09 - - - 2.7982 0.9997 221125_WJC_METTL3_EV_vs_WT_F03.08130.08130.2 0.00244 16-Aug K.TAVC[160.03]DIPPR[166.11].G "sp|P04350|TBB4A_HUMAN,sp|Q9BVA1|TBB2B_HUMAN,sp|A6NNZ2|TBB8B_HUMAN,sp|P07437|TBB5_HUMAN,sp|Q13885|TBB2A_HUMAN,sp|P68371|TBB4B_HUMAN,sp|Q3ZCM7|TBB8_HUMAN,tr|Q5ST81|Q5ST81_HUMAN,tr|Q5JP53|Q5JP53_HUMAN,tr|A0A075B736|A0A075B736_HUMAN,tr|Q5SQY0|Q5SQY0_HUMAN" 11 1037.5203 1.5 25870 8130 2 1037.519976 519.7674 Tubulin beta-4A chain OS=Homo sapiens OX=9606 GN=TUBB4A PE=1 SV=2 5.5 2013.5 - 268310 - - - -0.346 - 1.577 0.427 - 213.8 1 2 0 -0.0004 9 0 0 0 1.96E+07 1.30E+07 - - - 3.5126 0.9969 221125_WJC_METTL3_EV_vs_WT_F03.08131.08131.2 0.172 18-Jun K.IMQEEGQPLK.L "sp|Q96A33|CCD47_HUMAN,tr|A0A087WYW6|A0A087WYW6_HUMAN" 2 1171.5907 1.06 25871 8131 2 1171.590743 586.8026 PAT complex subunit CCDC47 OS=Homo sapiens OX=9606 GN=CCDC47 PE=1 SV=1 4.53 2013.6 - 197884 - - - 0.029 - 1.26 0.239 - 61.6 1 2 0 0 10 0 0 0 5.84E+06 5.48E+06 - - - 1.4513 0.9996 221125_WJC_METTL3_EV_vs_WT_F03.08134.08134.2 0.0209 14-Aug R.VIEC[160.03]DVVK.D "sp|Q96PK6|RBM14_HUMAN,tr|B8ZZ74|B8ZZ74_HUMAN,tr|F8WDX3|F8WDX3_HUMAN,tr|A0A0A0MSL8|A0A0A0MSL8_HUMAN,tr|A0A0A6YYI9|A0A0A6YYI9_HUMAN" 5 960.495 1.62 25872 8134 2 960.494642 481.2548 RNA-binding protein 14 OS=Homo sapiens OX=9606 GN=RBM14 PE=1 SV=2 4.37 2014 - 7.83E+06 - - - -0.3915 - 1.606 0.365 - 209.5 1 2 0 -0.0004 8 0 0 0 2.85E+09 1.76E+09 - - - 3.1656 0.8797 221125_WJC_METTL3_EV_vs_WT_F03.08135.08135.2 0.198 12-Jul K.LVELTQK.P "sp|Q9NP80|PLPL8_HUMAN,sp|P42704|LPPRC_HUMAN,tr|A0A804HI14|A0A804HI14_HUMAN,tr|A0A804HL40|A0A804HL40_HUMAN,tr|A0A804HKJ0|A0A804HKJ0_HUMAN,tr|A0A804HKR3|A0A804HKR3_HUMAN,tr|A0A804HIN4|A0A804HIN4_HUMAN,tr|A0A804HJG8|A0A804HJG8_HUMAN,tr|A0A804HLG8|A0A804HLG8_HUMAN,tr|A0A804HHY9|A0A804HHY9_HUMAN,tr|A0A804HI44|A0A804HI44_HUMAN,tr|A0A804HI40|A0A804HI40_HUMAN,tr|A0A804HJZ1|A0A804HJZ1_HUMAN,tr|A0A804HIQ7|A0A804HIQ7_HUMAN,tr|A0A804HK30|A0A804HK30_HUMAN,tr|A0A0C4DG51|A0A0C4DG51_HUMAN,tr|A0A804HKI2|A0A804HKI2_HUMAN,tr|A0A804HJI0|A0A804HJI0_HUMAN,tr|A0A804HIG4|A0A804HIG4_HUMAN" 19 829.4909 0.74 25873 8135 2 829.490588 415.7527 Calcium-independent phospholipase A2-gamma OS=Homo sapiens OX=9606 GN=PNPLA8 PE=1 SV=1 6 2014.1 - 2.62E+06 - - - -0.399 - 1.459 0.198 - 131.2 1 1 0 -0.0003 7 0 0 0 1.09E+08 1.46E+08 - - - 1.7002 0.998 221125_WJC_METTL3_EV_vs_WT_F03.08136.08136.2 0.161 14-Jul K.AEGLLQGK[136.11].H "sp|Q9UGN5|PARP2_HUMAN,tr|G3V167|G3V167_HUMAN" 2 822.4691 1.31 25874 8136 2 822.46953 412.2418 Poly [ADP-ribose] polymerase 2 OS=Homo sapiens OX=9606 GN=PARP2 PE=1 SV=2 6.05 2014.2 - 599066 - - - 0.5617 - 1.303 0.273 - 112.2 1 2 0 0.0005 8 0 0 0 1.92E+08 1.46E+08 - - - 1.8555 0.9997 221125_WJC_METTL3_EV_vs_WT_F03.08140.08140.2 0.117 16-Oct R.QLGSAALAR[166.11].H "sp|Q8N6H7|ARFG2_HUMAN,tr|H0YDX1|H0YDX1_HUMAN,tr|E9PIY6|E9PIY6_HUMAN,tr|E9PJT7|E9PJT7_HUMAN,tr|E9PN48|E9PN48_HUMAN,tr|E9PK28|E9PK28_HUMAN,tr|H0YF45|H0YF45_HUMAN,tr|G5E9L0|G5E9L0_HUMAN" 8 895.5115 1.07 25876 8140 2 895.511605 448.763 ADP-ribosylation factor GTPase-activating protein 2 OS=Homo sapiens OX=9606 GN=ARFGAP2 PE=1 SV=1 9.75 2014.7 - 1.06E+07 - - - 0.134 - 2.091 0.352 - 502.2 1 2 0 0.0001 9 0 0 0 3.89E+08 3.63E+08 - - - 3.7749 0.998 221125_WJC_METTL3_EV_vs_WT_F03.08141.08141.2 0.175 14-Aug K.APTNIVYK.L "sp|P15927|RFA2_HUMAN,tr|Q5TEJ7|Q5TEJ7_HUMAN" 2 904.5018 1.1 25877 8141 2 904.501083 453.2582 Replication protein A 32 kDa subunit OS=Homo sapiens OX=9606 GN=RPA2 PE=1 SV=1 8.63 2014.7 - 5.58E+06 - - - -0.8126 - 1.609 0.19 - 227.6 1 2 0 -0.0007 8 0 0 0 6.93E+08 6.29E+08 - - - 1.8785 0.9998 221125_WJC_METTL3_EV_vs_WT_F03.08149.08149.2 0.0172 20-Dec R.AVVGVVAGGGR[166.11].L "sp|P62917|RL8_HUMAN,tr|E9PKZ0|E9PKZ0_HUMAN,tr|E9PP36|E9PP36_HUMAN,tr|E9PKU4|E9PKU4_HUMAN" 4 950.5537 1.04 25882 8149 2 950.553428 476.2841 60S ribosomal protein L8 OS=Homo sapiens OX=9606 GN=RPL8 PE=1 SV=2 9.79 2015.7 - 3.07E+06 - - - -0.2693 - 2.301 0.353 - 527 1 2 0 -0.0003 11 0 0 0 6.14E+08 5.88E+08 - - - 3.9026 0.9998 221125_WJC_METTL3_EV_vs_WT_F03.08157.08157.2 0.132 20-Nov R.AVVGVVAGGGR.L "sp|P62917|RL8_HUMAN,tr|E9PKZ0|E9PKZ0_HUMAN,tr|E9PP36|E9PP36_HUMAN,tr|E9PKU4|E9PKU4_HUMAN" 4 940.5454 1.01 25885 8157 2 940.545307 471.28 60S ribosomal protein L8 OS=Homo sapiens OX=9606 GN=RPL8 PE=1 SV=2 9.79 2016.8 - 5.04E+06 - - - -0.1138 - 2.309 0.343 - 512.3 1 2 0 -0.0001 11 0 0 0 6.22E+08 6.15E+08 - - - 3.8381 0.9871 221125_WJC_METTL3_EV_vs_WT_F03.08164.08164.2 0.0841 12-Jun K.VSYSLAK.S "sp|Q92896|GSLG1_HUMAN,tr|H3BM42|H3BM42_HUMAN" 2 766.4225 1.47 25887 8164 2 766.42201 384.2185 Golgi apparatus protein 1 OS=Homo sapiens OX=9606 GN=GLG1 PE=1 SV=2 8.56 2017.8 - 1.89E+06 - - - -0.6459 - 1.326 0.093 - 92.7 2 2 0 -0.0005 7 0 0 0 6.54E+07 4.44E+07 - - - 0.4873 0.9999 221125_WJC_METTL3_EV_vs_WT_F03.08165.08165.2 4.10E-07 20-Oct R.YLSGADAGVDR[166.11].G sp|Q9BRD0|BUD13_HUMAN 1 1132.5388 0.82 25888 8165 2 1132.53748 567.2767 BUD13 homolog OS=Homo sapiens OX=9606 GN=BUD13 PE=1 SV=1 4.21 2017.9 - 464682 - - - -1.1849 - 1.956 0.582 - 251.9 1 2 0 -0.0013 11 0 0 0 2.63E+07 3.19E+07 - - - 5.1542 0.9905 221125_WJC_METTL3_EV_vs_WT_F03.08168.08168.2 1.09E-05 18-Sep L.SAMMGAVAEK[136.11].K "sp|Q86U44|MTA70_HUMAN,tr|F5H6D8|F5H6D8_HUMAN,tr|H0YFV6|H0YFV6_HUMAN,tr|B4DTN4|B4DTN4_HUMAN" 4 1001.4765 0.03 25889 8168 2 1001.476193 501.7455 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 5.72 2018.3 - 4.98E+06 - - - -0.3445 - 1.835 0.497 - 258.1 1 1 0 -0.0003 10 0 0 0 1.45E+07 4.19E+08 - - - 4.4062 0.9993 221125_WJC_METTL3_EV_vs_WT_F03.08170.08170.2 0.0154 16-Aug K.TFATSSGLK[136.11].Q "sp|Q03112|MECOM_HUMAN,sp|Q9HAZ2|PRD16_HUMAN,tr|H9KVD4|H9KVD4_HUMAN,tr|E7EUL6|E7EUL6_HUMAN,tr|A0A0C3SFZ7|A0A0C3SFZ7_HUMAN,tr|D6RDW0|D6RDW0_HUMAN,tr|D6RFY3|D6RFY3_HUMAN,tr|H0YA13|H0YA13_HUMAN" 8 918.4902 1.24 25891 8170 2 918.490169 460.2524 Histone-lysine N-methyltransferase MECOM OS=Homo sapiens OX=9606 GN=MECOM PE=1 SV=3 8.41 2018.4 - 1.23E+06 - - - -0.0305 - 1.568 0.314 - 158.3 1 2 0 0 9 0 0 0 8.71E+07 7.03E+07 - - - 2.6615 0.9709 221125_WJC_METTL3_EV_vs_WT_F03.08173.08173.2 2.87 12-Jun K.HVAYIIR.S "sp|P31025|LCN1_HUMAN,sp|Q5VSP4|LC1L1_HUMAN" 2 870.5076 2.44 25893 8173 2 870.507435 436.2611 Lipocalin-1 OS=Homo sapiens OX=9606 GN=LCN1 PE=1 SV=1 8.75 2018.8 - 3.37E+06 - - - -0.1574 - 1.185 0.063 - 145.4 2 2 0 -0.0001 7 0 0 0 1.48E+08 6.08E+07 - - - -0.0904 0.9996 221125_WJC_METTL3_EV_vs_WT_F03.08175.08175.2 0.00884 12-Aug K.HAIPIIK.E "sp|O00571|DDX3X_HUMAN,sp|O15523|DDX3Y_HUMAN,tr|A0A2R8YFR4|A0A2R8YFR4_HUMAN,tr|A0A2R8YCW1|A0A2R8YCW1_HUMAN,tr|A0A2R8YDH3|A0A2R8YDH3_HUMAN,tr|A0A2R8YDT5|A0A2R8YDT5_HUMAN,tr|A0A2R8Y645|A0A2R8Y645_HUMAN,tr|A0A2R8YF78|A0A2R8YF78_HUMAN,tr|C9J8G5|C9J8G5_HUMAN,tr|A0A2R8Y4D2|A0A2R8Y4D2_HUMAN,tr|A0A0D9SFB3|A0A0D9SFB3_HUMAN,tr|A0A2R8YFS5|A0A2R8YFS5_HUMAN,tr|A0A0D9SF53|A0A0D9SF53_HUMAN,tr|C9J081|C9J081_HUMAN,tr|A0A2R8Y5G6|A0A2R8Y5G6_HUMAN,tr|A0A2R8Y7T2|A0A2R8Y7T2_HUMAN,tr|A0A0D9SG12|A0A0D9SG12_HUMAN,tr|F6S8Q4|F6S8Q4_HUMAN,tr|A0A2U3TZJ9|A0A2U3TZJ9_HUMAN,tr|A0A2R8Y4A4|A0A2R8Y4A4_HUMAN" 20 790.5065 1.18 25894 8175 2 790.506044 396.2605 ATP-dependent RNA helicase DDX3X OS=Homo sapiens OX=9606 GN=DDX3X PE=1 SV=3 8.76 2019 - 7.55E+06 - - - -0.5882 - 1.862 0.316 - 345.2 1 2 0 -0.0005 7 0 0 0 5.57E+08 4.73E+08 - - - 3.3446 0.9997 221125_WJC_METTL3_EV_vs_WT_F03.08181.08181.2 1.29E-05 20-Nov R.YLSGADAGVDR.G sp|Q9BRD0|BUD13_HUMAN 1 1122.5306 0.77 25898 8181 2 1122.528339 562.2726 BUD13 homolog OS=Homo sapiens OX=9606 GN=BUD13 PE=1 SV=1 4.21 2019.7 - 765760 - - - -1.9714 - 2.074 0.516 - 289 1 2 0 -0.0022 11 0 0 0 2.51E+07 3.24E+07 - - - 4.8249 0.9929 221125_WJC_METTL3_EV_vs_WT_F03.08194.08194.2 0.871 12-Aug R.NQLLETR.W sp|Q6KB66|K2C80_HUMAN 1 872.4716 3.56 25906 8194 2 872.471238 437.2431 "Keratin, type II cytoskeletal 80 OS=Homo sapiens OX=9606 GN=KRT80 PE=1 SV=2" 6 2021.2 - 2.66E+06 - - - -0.392 - 1.599 0.045 - 358.6 1 2 0 -0.0003 7 0 0 0 2.42E+08 6.78E+07 - - - 0.8605 0.9451 221125_WJC_METTL3_EV_vs_WT_F03.08198.08198.2 4.77 12-May K.EVSTYIK[136.11].K "sp|P68104|EF1A1_HUMAN,sp|Q5VTE0|EF1A3_HUMAN,tr|A0A7I2V659|A0A7I2V659_HUMAN,tr|A0A7I2V3H3|A0A7I2V3H3_HUMAN,tr|A0A7I2V5N4|A0A7I2V5N4_HUMAN,tr|A0A087WVQ9|A0A087WVQ9_HUMAN,tr|A0A087WV01|A0A087WV01_HUMAN" 7 846.4578 0.37 25908 8198 2 846.457237 424.2362 Elongation factor 1-alpha 1 OS=Homo sapiens OX=9606 GN=EEF1A1 PE=1 SV=1 6.1 2021.8 - 2.13E+06 - - - -0.7053 - 1.02 0.089 - 101.8 3 2 0 -0.0006 7 0 0 0 2.59E+09 7.00E+09 - - - -0.4522 0.8236 221125_WJC_METTL3_EV_vs_WT_F03.08200.08200.2 6.38 14-May K.K[136.11]C[160.03]VC[160.03]EIER[166.11].R "sp|Q92619|HMHA1_HUMAN,tr|K7ES98|K7ES98_HUMAN,tr|K7EM85|K7EM85_HUMAN,tr|F5H1R4|F5H1R4_HUMAN,tr|K7ES92|K7ES92_HUMAN" 5 1110.5281 0 25909 8200 2 1110.531152 556.2713 Rho GTPase-activating protein 45 OS=Homo sapiens OX=9606 GN=ARHGAP45 PE=1 SV=2 6.13 2022 - 605488 - - - 2.7753 - 1.103 0.064 - 91 4 2 0 0.0031 8 0 0 0 6.69E+05 1.54E+08 - - - -0.4605 0.9997 221125_WJC_METTL3_EV_vs_WT_F03.08203.08203.2 0.0175 20-Oct R.TVEVAEGEAVR[166.11].T "sp|Q86UE4|LYRIC_HUMAN,tr|H0YB56|H0YB56_HUMAN,tr|E5RJU9|E5RJU9_HUMAN" 3 1168.5963 0.91 25911 8203 2 1168.595879 585.3054 Protein LYRIC OS=Homo sapiens OX=9606 GN=MTDH PE=1 SV=2 4.25 2022.3 - 533377 - - - -0.3919 - 1.906 0.399 - 285.1 1 2 0 -0.0005 11 0 0 0 5.25E+07 5.75E+07 - - - 3.7328 0.9479 221125_WJC_METTL3_EV_vs_WT_F03.08208.08208.2 3.30E-05 18-Aug R.MFGGPGTASR.P "sp|P08670|VIME_HUMAN,tr|B0YJC4|B0YJC4_HUMAN,tr|A0A1B0GVG8|A0A1B0GVG8_HUMAN,tr|A0A1B0GTT5|A0A1B0GTT5_HUMAN" 4 979.4546 1.53 25914 8208 2 979.451635 490.7346 Vimentin OS=Homo sapiens OX=9606 GN=VIM PE=1 SV=4 9.5 2022.9 - 904573 - - - -2.9761 - 1.812 0.451 - 239.7 1 1 0 -0.0029 10 0 0 0 1.89E+09 1.23E+09 - - - 4.0304 0.8672 221125_WJC_METTL3_EV_vs_WT_F03.08209.08209.2 0.00247 28-Jun R.SDSPVPTAPTSGGPK[136.11].P "sp|Q86U44|MTA70_HUMAN,tr|B4E349|B4E349_HUMAN,tr|F5H6D8|F5H6D8_HUMAN,tr|B4DTN4|B4DTN4_HUMAN" 4 1404.6976 0.001 25915 8209 2 1404.696676 703.3561 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 5.55 2023.1 - 144430 - - - -0.6749 - 1.091 0.325 - 79.4 1 1 0 -0.0009 15 0 0 0 0.00E+00 1.26E+07 - - - 1.6553 0.9998 221125_WJC_METTL3_EV_vs_WT_F03.08210.08210.2 0.000327 16-Oct K.VIDDTNITR[166.11].L "sp|P05783|K1C18_HUMAN,tr|F8VZY9|F8VZY9_HUMAN" 2 1055.5487 1.99 25916 8210 2 1055.548029 528.7816 "Keratin, type I cytoskeletal 18 OS=Homo sapiens OX=9606 GN=KRT18 PE=1 SV=2" 4.21 2023.1 - 3.13E+06 - - - -0.5959 - 1.962 0.48 - 315 1 2 0 -0.0006 9 0 0 0 2.91E+08 1.47E+08 - - - 4.5359 0.9979 221125_WJC_METTL3_EV_vs_WT_F03.08211.08211.2 0.000175 20-Dec R.TVEVAEGEAVR.T "sp|Q86UE4|LYRIC_HUMAN,tr|H0YB56|H0YB56_HUMAN,tr|E5RJU9|E5RJU9_HUMAN" 3 1158.5881 0.94 25917 8211 2 1158.582611 580.3013 Protein LYRIC OS=Homo sapiens OX=9606 GN=MTDH PE=1 SV=2 4.25 2023.2 - 524249 - - - -4.7092 - 2.161 0.476 - 488 1 2 0 -0.0055 11 0 0 0 5.21E+07 5.53E+07 - - - 4.6396 0.9992 221125_WJC_METTL3_EV_vs_WT_F03.08214.08214.2 0.0275 14-Aug K.FVEEQNLK.D "sp|Q16875|F263_HUMAN,tr|A0A1W2PR17|A0A1W2PR17_HUMAN,tr|Q5W015|Q5W015_HUMAN,tr|F2Z2I2|F2Z2I2_HUMAN,tr|Q5VX20|Q5VX20_HUMAN" 5 1005.5131 6.02 25918 8214 2 1005.512531 503.7638 "6-phosphofructo-2-kinase\fructose-2,6-bisphosphatase 3 OS=Homo sapiens OX=9606 GN=PFKFB3 PE=1 SV=1" 4.53 2023.6 - 1.28E+07 - - - -0.5768 - 1.588 0.295 - 171.7 1 2 0 -0.0006 8 0 0 0 7.84E+08 1.30E+08 - - - 2.6145 0.9995 221125_WJC_METTL3_EV_vs_WT_F03.08215.08215.2 0.00266 12-Aug R.MYSYPAR.V "sp|P07910|HNRPC_HUMAN,tr|B4DY08|B4DY08_HUMAN,tr|G3V575|G3V575_HUMAN,tr|G3V5V7|G3V5V7_HUMAN,tr|B2R5W2|B2R5W2_HUMAN,tr|G3V4C1|G3V4C1_HUMAN,tr|G3V576|G3V576_HUMAN,tr|G3V2D6|G3V2D6_HUMAN,tr|G3V4W0|G3V4W0_HUMAN,tr|G3V555|G3V555_HUMAN,tr|G3V2Q1|G3V2Q1_HUMAN" 11 886.4007 1.14 25919 8215 2 886.40093 444.2076 Heterogeneous nuclear ribonucleoproteins C1\C2 OS=Homo sapiens OX=9606 GN=HNRNPC PE=1 SV=4 8.34 2023.7 - 2.68E+06 - - - 0.2324 - 1.394 0.403 - 233.9 1 2 0 0.0002 7 0 0 0 1.07E+09 9.36E+08 - - - 3.07 0.9932 221125_WJC_METTL3_EV_vs_WT_F03.08218.08218.2 1.95 14-Jul R.VLLGETGK.E "sp|P62280|RS11_HUMAN,tr|M0QZC5|M0QZC5_HUMAN,tr|M0R1H6|M0R1H6_HUMAN" 3 815.4753 0.94 25920 8218 2 815.476838 408.7449 40S ribosomal protein S11 OS=Homo sapiens OX=9606 GN=RPS11 PE=1 SV=3 5.97 2024.1 - 7.44E+06 - - - 1.924 - 1.446 0.176 - 182.7 1 2 0 0.0016 8 0 0 0 4.03E+08 4.28E+08 - - - 1.4527 0.8967 221125_WJC_METTL3_EV_vs_WT_F03.08219.08219.2 0.0104 16-Jul Y.LGGEQSYYR.A sp|Q12948|FOXC1_HUMAN 1 1071.4985 2.25 25921 8219 2 1071.497819 536.7565 Forkhead box protein C1 OS=Homo sapiens OX=9606 GN=FOXC1 PE=1 SV=3 6 2024.2 - 858158 - - - -0.657 - 1.411 0.249 - 154 1 1 0 -0.0007 9 0 0 0 7.39E+07 3.29E+07 - - - 1.876 0.9868 221125_WJC_METTL3_EV_vs_WT_F03.08220.08220.2 0.00061 18-Oct R.MFGGPGTASR[166.11].P "sp|P08670|VIME_HUMAN,tr|B0YJC4|B0YJC4_HUMAN,tr|A0A1B0GVG8|A0A1B0GVG8_HUMAN,tr|A0A1B0GTT5|A0A1B0GTT5_HUMAN" 4 989.4628 1.54 25922 8220 2 989.462856 495.7387 Vimentin OS=Homo sapiens OX=9606 GN=VIM PE=1 SV=4 9.5 2024.3 - 727021 - - - 0.0364 - 1.566 0.494 - 285.3 1 1 0 0 10 0 0 0 1.90E+09 1.23E+09 - - - 3.9416 0.9968 221125_WJC_METTL3_EV_vs_WT_F03.08226.08226.2 0.0867 12-Jul K.EIEQVYR.Q "sp|Q8NEY8|PPHLN_HUMAN,tr|B7Z8L1|B7Z8L1_HUMAN,tr|F8W6A0|F8W6A0_HUMAN,tr|F8W0Q9|F8W0Q9_HUMAN,tr|F8WF16|F8WF16_HUMAN" 5 935.4712 1.45 25924 8226 2 935.471564 468.7429 Periphilin-1 OS=Homo sapiens OX=9606 GN=PPHLN1 PE=1 SV=2 4.53 2025 - 793784 - - - 0.3399 - 1.447 0.17 - 239.2 1 2 0 0.0003 7 0 0 0 1.69E+08 1.17E+08 - - - 1.4673 0.9793 221125_WJC_METTL3_EV_vs_WT_F03.08236.08236.2 0.000434 16-Oct Y.LGGEQSYYR[166.11].A sp|Q12948|FOXC1_HUMAN 1 1081.5068 2.25 25929 8236 2 1081.50532 541.7607 Forkhead box protein C1 OS=Homo sapiens OX=9606 GN=FOXC1 PE=1 SV=3 6 2026.2 - 1.06E+06 - - - -1.362 - 2.001 0.375 - 312.2 1 1 0 -0.0015 9 0 0 0 7.39E+07 3.29E+07 - - - 3.817 0.9957 221125_WJC_METTL3_EV_vs_WT_F03.08245.08245.2 0.000453 20-Nov R.VAVVGNVDAGK[136.11].S "sp|O00178|GTPB1_HUMAN,tr|F5H716|F5H716_HUMAN" 2 1035.5804 0.55 25932 8245 2 1035.584593 518.7975 GTP-binding protein 1 OS=Homo sapiens OX=9606 GN=GTPBP1 PE=1 SV=3 5.81 2027.4 - 631564 - - - 4.0402 - 2.169 0.273 - 369 1 2 0 0.0042 11 0 0 0 4.02E+07 7.32E+07 - - - 3.1506 0.9981 221125_WJC_METTL3_EV_vs_WT_F03.08248.08248.2 0.0212 14-Aug K.NLSEAQLR.K sp|Q9NZT1|CALL5_HUMAN 1 929.493 66.2 25933 8248 2 929.491717 465.7538 Calmodulin-like protein 5 OS=Homo sapiens OX=9606 GN=CALML5 PE=1 SV=2 6 2027.8 - 2.05E+06 - - - -1.4277 - 1.38 0.292 - 211.9 1 2 0 -0.0013 8 0 0 0 2.53E+09 3.83E+07 - - - 2.1687 0.8806 221125_WJC_METTL3_EV_vs_WT_F03.08250.08250.2 3.54 16-Sep K.LGAFQAQEK[136.11].E "sp|P49642|PRI1_HUMAN,tr|F8VSB2|F8VSB2_HUMAN,tr|A0A5F9ZHB6|A0A5F9ZHB6_HUMAN,tr|F8VNY2|F8VNY2_HUMAN" 4 998.5276 0.33 25934 8250 2 998.524174 500.2711 DNA primase small subunit OS=Homo sapiens OX=9606 GN=PRIM1 PE=1 SV=1 6 2028 - 2.09E+06 - - - -3.4761 - 1.446 0.003 - 224.7 1 2 0 -0.0035 9 0 0 0 3.13E+07 9.61E+07 - - - 0.129 0.9993 221125_WJC_METTL3_EV_vs_WT_F03.08254.08254.2 0.00196 18-Nov K.VVGC[160.03]SC[160.03]VVVK[136.11].D sp|P25398|RS12_HUMAN 1 1113.5766 1.77 25936 8254 2 1113.574211 557.7956 40S ribosomal protein S12 OS=Homo sapiens OX=9606 GN=RPS12 PE=1 SV=3 8.03 2028.5 - 646608 - - - -2.1337 - 1.65 0.425 - 235.6 1 2 0 -0.0024 10 0 0 0 1.01E+09 5.68E+08 - - - 3.5771 0.9943 221125_WJC_METTL3_EV_vs_WT_F03.08262.08262.2 0.316 16-Aug K.TVGATALPR.L "sp|P50990|TCPQ_HUMAN,tr|H7C4C8|H7C4C8_HUMAN" 2 884.508 0.34 25940 8262 2 884.506894 443.2613 T-complex protein 1 subunit theta OS=Homo sapiens OX=9606 GN=CCT8 PE=1 SV=4 9.41 2029.3 - 9.47E+06 - - - -1.212 - 1.366 0.172 - 166.1 1 2 0 -0.0011 9 0 0 0 1.25E+09 3.68E+09 - - - 1.2134 1 221125_WJC_METTL3_EV_vs_WT_F03.08271.08271.2 3.46E-07 16-Oct R.PVIDNPNYK.G "sp|P27824|CALX_HUMAN,tr|A0A7P0T937|A0A7P0T937_HUMAN,tr|A0A7P0T840|A0A7P0T840_HUMAN,tr|A0A7P0TB65|A0A7P0TB65_HUMAN,tr|A0A7P0TAE9|A0A7P0TAE9_HUMAN,tr|D6RGY2|D6RGY2_HUMAN,tr|A0A7P0T8G1|A0A7P0T8G1_HUMAN,tr|A0A7P0Z4D6|A0A7P0Z4D6_HUMAN,tr|A0A7P0Z484|A0A7P0Z484_HUMAN,tr|A0A7P0TAR9|A0A7P0TAR9_HUMAN,tr|A0A7P0T9L0|A0A7P0T9L0_HUMAN" 11 1058.5397 1.26 25946 8271 2 1058.539344 530.2771 Calnexin OS=Homo sapiens OX=9606 GN=CANX PE=1 SV=2 6.26 2030.3 - 1.85E+06 - - - -0.2985 - 2.276 0.587 - 318 1 1 0 -0.0003 9 0 0 0 1.86E+08 1.48E+08 - - - 5.7558 0.8819 221125_WJC_METTL3_EV_vs_WT_F03.08278.08278.2 0.484 14-Jun R.YQGLVDGR[166.11].K sp|Q96JB3|HIC2_HUMAN 1 916.4642 0.03 25949 8278 2 916.460987 459.2394 Hypermethylated in cancer 2 protein OS=Homo sapiens OX=9606 GN=HIC2 PE=1 SV=2 5.84 2031.2 - 659877 - - - -3.5059 - 0.947 0.191 - 99.2 2 2 0 -0.0032 8 0 0 0 3.57E+07 1.30E+09 - - - 0.152 0.9992 221125_WJC_METTL3_EV_vs_WT_F03.08280.08280.2 0.021 18-Oct R.TVAVITSDGR[166.11].M "sp|O95777|LSM8_HUMAN,tr|C9JNV3|C9JNV3_HUMAN,tr|F2Z2Y6|F2Z2Y6_HUMAN" 3 1027.5537 2.88 25950 8280 2 1027.555006 514.7841 U6 snRNA-associated Sm-like protein LSm8 OS=Homo sapiens OX=9606 GN=LSM8 PE=1 SV=3 5.5 2031.4 - 2.12E+06 - - - 1.2282 - 2.014 0.262 - 325 1 2 0 0.0013 10 0 0 0 3.39E+08 1.18E+08 - - - 2.93 0.9997 221125_WJC_METTL3_EV_vs_WT_F03.08281.08281.2 0.0919 18-Oct R.MIETAQVDER[166.11].A sp|Q9UL25|RAB21_HUMAN 1 1200.5684 1.18 25951 8281 2 1200.566418 601.2915 Ras-related protein Rab-21 OS=Homo sapiens OX=9606 GN=RAB21 PE=1 SV=3 4.14 2031.5 - 544501 - - - -1.6575 - 2.04 0.413 - 295.6 1 2 0 -0.002 10 0 0 0 5.56E+07 4.69E+07 - - - 4.0809 0.992 221125_WJC_METTL3_EV_vs_WT_F03.08282.08282.2 0.462 12-Jun R.SQAPLLR.W "sp|P09601|HMOX1_HUMAN,tr|A0A7I2V3M0|A0A7I2V3M0_HUMAN,tr|A0A7I2V277|A0A7I2V277_HUMAN" 3 783.4603 2.03 25952 8282 2 783.459975 392.7374 Heme oxygenase 1 OS=Homo sapiens OX=9606 GN=HMOX1 PE=1 SV=1 9.47 2031.6 - 909615 - - - -0.3982 - 1.099 0.195 - 116.9 1 2 0 -0.0003 7 0 0 0 4.45E+07 2.19E+07 - - - 0.7803 0.9999 221125_WJC_METTL3_EV_vs_WT_F03.08287.08287.2 8.81E-06 18-Oct K.VVGC[160.03]SC[160.03]VVVK.D sp|P25398|RS12_HUMAN 1 1105.5624 1.77 25955 8287 2 1105.5614 553.7885 40S ribosomal protein S12 OS=Homo sapiens OX=9606 GN=RPS12 PE=1 SV=3 8.03 2032.2 - 1.06E+07 - - - -0.8928 - 2.111 0.61 - 236.4 1 2 0 -0.001 10 0 0 0 1.01E+09 5.68E+08 - - - 5.6317 0.9998 221125_WJC_METTL3_EV_vs_WT_F03.08288.08288.2 0.00134 18-Nov R.TVAVITSDGR.M "sp|O95777|LSM8_HUMAN,tr|C9JNV3|C9JNV3_HUMAN,tr|F2Z2Y6|F2Z2Y6_HUMAN" 3 1017.5455 2.88 25956 8288 2 1017.545719 509.78 U6 snRNA-associated Sm-like protein LSm8 OS=Homo sapiens OX=9606 GN=LSM8 PE=1 SV=3 5.5 2032.2 - 6.33E+06 - - - 0.2408 - 2.158 0.413 - 391.7 1 2 0 0.0002 10 0 0 0 3.39E+08 1.18E+08 - - - 4.2384 0.9998 221125_WJC_METTL3_EV_vs_WT_F03.08295.08295.2 0.00148 20-Dec R.LLQSGNSDVVR.S sp|Q13835|PKP1_HUMAN 1 1186.6306 141.65 25961 8295 2 1186.630479 594.3226 Plakophilin-1 OS=Homo sapiens OX=9606 GN=PKP1 PE=1 SV=2 5.84 2033 - 1.41E+06 - - - -0.102 - 2.173 0.4 - 496.8 1 2 0 -0.0001 11 0 0 0 1.47E+08 1.04E+06 - - - 4.0949 0.992 221125_WJC_METTL3_EV_vs_WT_F03.08299.08299.3 0.0577 Aug-36 K.ILAHNNFVGR.L "sp|Q9NZI8|IF2B1_HUMAN,sp|O00425|IF2B3_HUMAN" 2 1139.62 1.09 25963 8299 3 1139.617459 380.8806 Insulin-like growth factor 2 mRNA-binding protein 1 OS=Homo sapiens OX=9606 GN=IGF2BP1 PE=1 SV=2 9.76 2033.4 - 3.13E+06 - - - -2.2086 - 1.699 0.208 - 60 1 2 0 -0.0025 10 0 0 0 7.91E+07 7.24E+07 - - - 2.4062 0.9995 221125_WJC_METTL3_EV_vs_WT_F03.08302.08302.2 0.0243 16-Sep K.FGNTEQGFK[136.11].F sp|P49792|RBP2_HUMAN 1 1034.4913 1.35 25964 8302 2 1034.489998 518.2529 E3 SUMO-protein ligase RanBP2 OS=Homo sapiens OX=9606 GN=RANBP2 PE=1 SV=2 6 2033.8 - 1.73E+06 - - - -1.2199 - 1.814 0.335 - 168 1 2 0 -0.0013 9 0 0 0 8.12E+07 6.02E+07 - - - 3.2378 0.9915 221125_WJC_METTL3_EV_vs_WT_F03.08307.08307.2 0.0613 14-Jun K.VVDSLYNK.A sp|O00231|PSD11_HUMAN 1 936.4916 0.7 25967 8307 2 936.490651 469.2531 26S proteasome non-ATPase regulatory subunit 11 OS=Homo sapiens OX=9606 GN=PSMD11 PE=1 SV=3 5.81 2034.5 - 3.42E+06 - - - -1.0635 - 1.283 0.189 - 84.9 5 2 0 -0.001 8 0 0 0 1.37E+08 1.97E+08 - - - 0.876 0.9997 221125_WJC_METTL3_EV_vs_WT_F03.08308.08308.2 0.000645 16-Oct K.ETSTEALMK.S "sp|Q86YP4|P66A_HUMAN,tr|C9JJK9|C9JJK9_HUMAN,tr|C9JGN4|C9JGN4_HUMAN" 3 1008.4798 1.88 25968 8308 2 1008.479511 505.2472 Transcriptional repressor p66-alpha OS=Homo sapiens OX=9606 GN=GATAD2A PE=1 SV=1 4.53 2034.6 - 1.50E+06 - - - -0.2489 - 1.791 0.404 - 345.9 1 2 0 -0.0003 9 0 0 0 4.59E+07 2.44E+07 - - - 3.7109 0.921 221125_WJC_METTL3_EV_vs_WT_F03.08318.08318.2 1.16 14-May R.GPPPSWGR.R sp|P84103|SRSF3_HUMAN 1 852.4242 0.24 25974 8318 2 852.421701 427.2194 Serine\arginine-rich splicing factor 3 OS=Homo sapiens OX=9606 GN=SRSF3 PE=1 SV=1 9.75 2035.8 - 946226 - - - -2.9739 - 1.08 0.142 - 68.9 2 2 0 -0.0025 8 0 0 0 3.05E+07 1.27E+08 - - - 0.1867 0.9983 221125_WJC_METTL3_EV_vs_WT_F03.08326.08326.2 0.0293 18-Aug R.LGLGEGAEEK[136.11].S "sp|P18754|RCC1_HUMAN,tr|C9JW69|C9JW69_HUMAN" 2 1009.5171 1.16 25977 8326 2 1009.518016 505.7658 Regulator of chromosome condensation OS=Homo sapiens OX=9606 GN=RCC1 PE=1 SV=1 4.25 2036.8 - 1.30E+06 - - - 0.8677 - 1.826 0.186 - 123.7 1 2 0 0.0009 10 0 0 0 1.38E+08 1.19E+08 - - - 2.0952 0.9994 221125_WJC_METTL3_EV_vs_WT_F03.08330.08330.2 0.025 16-Jul K.GFGDVGEAK.G "sp|Q14157|UBP2L_HUMAN,tr|F8W726|F8W726_HUMAN" 2 878.4134 2 25979 8330 2 878.411678 440.214 Ubiquitin-associated protein 2-like OS=Homo sapiens OX=9606 GN=UBAP2L PE=1 SV=2 4.37 2037.2 - 8.77E+06 - - - -1.9569 - 1.369 0.494 - 126.9 1 2 0 -0.0017 9 0 0 0 3.11E+09 1.55E+09 - - - 3.5978 0.9964 221125_WJC_METTL3_EV_vs_WT_F03.08334.08334.2 0.026 12-Jun K.DNNLLGK[136.11].F "sp|P54652|HSP72_HUMAN,sp|P11142|HSP7C_HUMAN,tr|E9PNE6|E9PNE6_HUMAN,tr|A8K7Q2|A8K7Q2_HUMAN,tr|E9PKE3|E9PKE3_HUMAN,tr|E9PM13|E9PM13_HUMAN,tr|E9PS65|E9PS65_HUMAN" 7 780.4221 0.19 25981 8334 2 780.420602 391.2183 Heat shock-related 70 kDa protein 2 OS=Homo sapiens OX=9606 GN=HSPA2 PE=1 SV=1 5.84 2037.7 - 3.91E+06 - - - -1.9425 - 1.293 0.276 - 120.5 1 2 0 -0.0015 7 0 0 0 1.08E+09 5.81E+09 - - - 1.8933 0.997 221125_WJC_METTL3_EV_vs_WT_F03.08335.08335.2 0.0217 12-Jun R.FSPTMGR[166.11].H "sp|P78344|IF4G2_HUMAN,tr|H0Y3P2|H0Y3P2_HUMAN,tr|H0YCH5|H0YCH5_HUMAN,tr|D3DQV9|D3DQV9_HUMAN" 4 804.3828 1.59 25982 8335 2 804.382034 403.1987 Eukaryotic translation initiation factor 4 gamma 2 OS=Homo sapiens OX=9606 GN=EIF4G2 PE=1 SV=1 9.75 2037.7 - 4.02E+06 - - - -0.9262 - 1.13 0.294 - 183.2 1 2 0 -0.0007 7 0 0 0 2.13E+08 1.34E+08 - - - 1.5995 0.9931 221125_WJC_METTL3_EV_vs_WT_F03.08336.08336.2 0.028 16-Sep K.FGNTEQGFK.F sp|P49792|RBP2_HUMAN 1 1026.4771 1.35 25983 8336 2 1026.476097 514.2458 E3 SUMO-protein ligase RanBP2 OS=Homo sapiens OX=9606 GN=RANBP2 PE=1 SV=2 6 2037.8 - 1.90E+06 - - - -0.9382 - 1.117 0.219 - 165.4 1 2 0 -0.001 9 0 0 0 8.62E+07 6.38E+07 - - - 0.9783 0.9982 221125_WJC_METTL3_EV_vs_WT_F03.08339.08339.2 0.296 12-Aug K.LNLTSPK.R "sp|Q8IWZ3|ANKH1_HUMAN,tr|A0A0A0MQZ8|A0A0A0MQZ8_HUMAN,tr|H0Y472|H0Y472_HUMAN,tr|H0Y7Y3|H0Y7Y3_HUMAN,tr|H0Y4P6|H0Y4P6_HUMAN,tr|H0Y785|H0Y785_HUMAN" 6 771.4491 1.35 25984 8339 2 771.448558 386.7318 Ankyrin repeat and KH domain-containing protein 1 OS=Homo sapiens OX=9606 GN=ANKHD1 PE=1 SV=1 8.75 2038.1 - 1.37E+06 - - - -0.6429 - 1.717 0.159 - 206.6 1 2 0 -0.0005 7 0 0 0 2.05E+08 1.52E+08 - - - 1.9281 0.9976 221125_WJC_METTL3_EV_vs_WT_F03.08341.08341.2 0.0959 12-Jun R.FSPTMGR.H "sp|P78344|IF4G2_HUMAN,tr|H0Y3P2|H0Y3P2_HUMAN,tr|H0YCH5|H0YCH5_HUMAN,tr|D3DQV9|D3DQV9_HUMAN" 4 794.3745 1.64 25985 8341 2 794.374197 398.1945 Eukaryotic translation initiation factor 4 gamma 2 OS=Homo sapiens OX=9606 GN=EIF4G2 PE=1 SV=1 9.75 2038.4 - 1.16E+07 - - - -0.3928 - 1.043 0.335 - 192.3 1 2 0 -0.0003 7 0 0 0 2.12E+08 1.30E+08 - - - 1.6486 0.9997 221125_WJC_METTL3_EV_vs_WT_F03.08344.08344.2 0.0025 22-Sep K.VIAAEGEMNASR.A sp|P27105|STOM_HUMAN 1 1246.5976 1.29 25986 8344 2 1246.597991 624.3061 Stomatin OS=Homo sapiens OX=9606 GN=STOM PE=1 SV=3 4.53 2038.8 - 208850 - - - 0.3249 - 1.683 0.454 - 193.3 1 2 0 0.0004 12 0 0 0 9.24E+06 7.19E+06 - - - 3.7638 0.993 221125_WJC_METTL3_EV_vs_WT_F03.08347.08347.2 0.0232 14-Jul K.GITEEC[160.03]LK[136.11].Q "sp|Q9UKV3|ACINU_HUMAN,tr|S4R3H4|S4R3H4_HUMAN,tr|E7EQT4|E7EQT4_HUMAN" 3 956.4728 1.02 25987 8347 2 956.469839 479.2437 Apoptotic chromatin condensation inducer in the nucleus OS=Homo sapiens OX=9606 GN=ACIN1 PE=1 SV=2 4.53 2039.1 - 776689 - - - -3.1303 - 1.465 0.253 - 140.7 1 2 0 -0.003 8 0 0 0 3.20E+07 3.15E+07 - - - 2.0604 0.9983 221125_WJC_METTL3_EV_vs_WT_F03.08351.08351.2 0.0106 12-Jul K.SC[160.03]ASLLR.V "sp|Q8WXI9|P66B_HUMAN,tr|A0A0U1RRM1|A0A0U1RRM1_HUMAN,tr|A0A0U1RR30|A0A0U1RR30_HUMAN" 3 805.4116 1.46 25988 8351 2 805.411103 403.7131 Transcriptional repressor p66-beta OS=Homo sapiens OX=9606 GN=GATAD2B PE=1 SV=1 7.96 2039.7 - 3.53E+06 - - - -0.6456 - 1.298 0.286 - 233 1 2 0 -0.0005 7 0 0 0 2.58E+08 1.77E+08 - - - 1.9797 0.9998 221125_WJC_METTL3_EV_vs_WT_F03.08352.08352.2 0.00107 20-Oct K.AANGVVLATEK[136.11].K "sp|P25787|PSA2_HUMAN,tr|A0A024RA52|A0A024RA52_HUMAN,tr|A0A7I2V2H3|A0A7I2V2H3_HUMAN" 3 1079.6066 0.74 25989 8352 2 1079.605336 540.8106 Proteasome subunit alpha type-2 OS=Homo sapiens OX=9606 GN=PSMA2 PE=1 SV=2 6.05 2039.9 - 314786 - - - -1.193 - 2.062 0.463 - 294.5 1 2 0 -0.0013 11 0 0 0 9.74E+07 1.31E+08 - - - 4.418 0.9991 221125_WJC_METTL3_EV_vs_WT_F03.08355.08355.2 0.0158 16-Jun K.GFGDVGEAK[136.11].G "sp|Q14157|UBP2L_HUMAN,tr|F8W726|F8W726_HUMAN" 2 886.4276 2 25990 8355 2 886.427128 444.2211 Ubiquitin-associated protein 2-like OS=Homo sapiens OX=9606 GN=UBAP2L PE=1 SV=2 4.37 2040.2 - 1.70E+07 - - - -0.5291 - 1.121 0.416 - 90.9 1 2 0 -0.0005 9 0 0 0 3.11E+09 1.56E+09 - - - 2.4439 0.9927 221125_WJC_METTL3_EV_vs_WT_F03.08360.08360.2 0.629 12-Jul R.FIAEVQK.R sp|Q9Y5V3|MAGD1_HUMAN 1 833.4647 1.39 25993 8360 2 833.463781 417.7396 Melanoma-associated antigen D1 OS=Homo sapiens OX=9606 GN=MAGED1 PE=1 SV=3 6 2040.9 - 2.12E+06 - - - -1.1074 - 1.482 0.096 - 156.3 1 2 0 -0.0009 7 0 0 0 7.85E+07 5.66E+07 - - - 0.9963 0.9902 221125_WJC_METTL3_EV_vs_WT_F03.08362.08362.2 0.319 12-Jun R.FIAEVQK[136.11].R sp|Q9Y5V3|MAGD1_HUMAN 1 841.4789 1.41 25995 8362 2 841.478429 421.7467 Melanoma-associated antigen D1 OS=Homo sapiens OX=9606 GN=MAGED1 PE=1 SV=3 6 2041 - 1.71E+06 - - - -0.5645 - 1.083 0.185 - 100.5 1 2 0 -0.0005 7 0 0 0 7.99E+07 5.66E+07 - - - 0.6599 0.9995 221125_WJC_METTL3_EV_vs_WT_F03.08364.08364.2 0.786 22-Oct K.VIAAEGEMNASR[166.11].A sp|P27105|STOM_HUMAN 1 1256.6059 1.29 25997 8364 2 1256.606228 629.3102 Stomatin OS=Homo sapiens OX=9606 GN=STOM PE=1 SV=3 4.53 2041.2 - 313955 - - - 0.296 - 1.819 0.341 - 175.3 1 2 0 0.0004 12 0 0 0 9.24E+06 7.19E+06 - - - 3.1337 0.9989 221125_WJC_METTL3_EV_vs_WT_F03.08368.08368.2 0.0194 12-Jun K.DNNLLGK.F "sp|P54652|HSP72_HUMAN,sp|P11142|HSP7C_HUMAN,tr|E9PNE6|E9PNE6_HUMAN,tr|A8K7Q2|A8K7Q2_HUMAN,tr|E9PKE3|E9PKE3_HUMAN,tr|E9PM13|E9PM13_HUMAN,tr|E9PS65|E9PS65_HUMAN" 7 772.4079 0.19 25999 8368 2 772.407702 387.2112 Heat shock-related 70 kDa protein 2 OS=Homo sapiens OX=9606 GN=HSPA2 PE=1 SV=1 5.84 2041.7 - 7.59E+06 - - - -0.2796 - 1.321 0.319 - 208.7 1 2 0 -0.0002 7 0 0 0 1.08E+09 5.80E+09 - - - 2.2792 0.9979 221125_WJC_METTL3_EV_vs_WT_F03.08373.08373.2 0.0121 14-Jul K.GITEEC[160.03]LK.Q "sp|Q9UKV3|ACINU_HUMAN,tr|S4R3H4|S4R3H4_HUMAN,tr|E7EQT4|E7EQT4_HUMAN" 3 948.4586 0.99 26003 8373 2 948.456791 475.2366 Apoptotic chromatin condensation inducer in the nucleus OS=Homo sapiens OX=9606 GN=ACIN1 PE=1 SV=2 4.53 2042.1 - 1.18E+06 - - - -1.9421 - 1.393 0.316 - 143 1 2 0 -0.0018 8 0 0 0 3.11E+07 3.14E+07 - - - 2.3741 0.9995 221125_WJC_METTL3_EV_vs_WT_F03.08374.08374.2 0.00104 18-Nov R.MVAAANEIAK[136.11].E "sp|Q8IWC1|MA7D3_HUMAN,tr|A0A0A0MRP0|A0A0A0MRP0_HUMAN" 2 1024.5467 2.31 26004 8374 2 1024.545466 513.2806 MAP7 domain-containing protein 3 OS=Homo sapiens OX=9606 GN=MAP7D3 PE=1 SV=2 5.75 2042.2 - 726545 - - - -1.1712 - 1.757 0.359 - 309.9 1 2 0 -0.0012 10 0 0 0 2.64E+08 1.15E+08 - - - 3.2654 0.9992 221125_WJC_METTL3_EV_vs_WT_F03.08378.08378.2 0.00872 12-Jun R.MYSYPAR[166.11].V "sp|P07910|HNRPC_HUMAN,tr|B4DY08|B4DY08_HUMAN,tr|G3V575|G3V575_HUMAN,tr|G3V5V7|G3V5V7_HUMAN,tr|B2R5W2|B2R5W2_HUMAN,tr|G3V4C1|G3V4C1_HUMAN,tr|G3V576|G3V576_HUMAN,tr|G3V2D6|G3V2D6_HUMAN,tr|G3V4W0|G3V4W0_HUMAN,tr|G3V555|G3V555_HUMAN,tr|G3V2Q1|G3V2Q1_HUMAN" 11 896.409 -1 26005 8378 2 896.407713 449.2118 Heterogeneous nuclear ribonucleoproteins C1\C2 OS=Homo sapiens OX=9606 GN=HNRNPC PE=1 SV=4 8.34 2042.8 - 1.50E+07 - - - -1.429 - 1.17 0.468 - 159.1 1 2 0 -0.0013 7 0 0 0 0.00E+00 0.00E+00 - - - 2.9947 0.9574 221125_WJC_METTL3_EV_vs_WT_F03.08383.08383.2 3.26 14-Aug K.TIDDLEEK[136.11].L "sp|P67936|TPM4_HUMAN,tr|A0A5F9UN72|A0A5F9UN72_HUMAN,tr|K7EPB9|K7EPB9_HUMAN,tr|K7ENT6|K7ENT6_HUMAN,tr|A0A2R8YE05|A0A2R8YE05_HUMAN" 5 969.4746 1.39 26010 8383 2 969.472516 485.7446 Tropomyosin alpha-4 chain OS=Homo sapiens OX=9606 GN=TPM4 PE=1 SV=3 3.92 2043.2 - 598848 - - - -2.1568 - 1.223 0.078 - 198.1 1 2 0 -0.0021 8 0 0 0 6.17E+07 4.44E+07 - - - 0.2236 0.9552 221125_WJC_METTL3_EV_vs_WT_F03.08389.08389.2 6.38E-05 16-Aug L.FYTNEEVAK[136.11].N "sp|P43243|MATR3_HUMAN,tr|B3KM87|B3KM87_HUMAN,tr|A8MXP9|A8MXP9_HUMAN,tr|A0A0R4J2E8|A0A0R4J2E8_HUMAN" 4 1107.5328 1.35 26013 8389 2 1107.530056 554.7737 Matrin-3 OS=Homo sapiens OX=9606 GN=MATR3 PE=1 SV=2 4.53 2043.9 - 2.65E+06 - - - -2.4685 - 1.413 0.503 - 155 1 1 0 -0.0027 9 0 0 0 1.40E+08 1.04E+08 - - - 3.7555 0.9333 221125_WJC_METTL3_EV_vs_WT_F03.08391.08391.2 0.0151 12-Jun E.FFETSAK.D "sp|Q96E17|RAB3C_HUMAN,sp|P51153|RAB13_HUMAN,sp|P61026|RAB10_HUMAN,tr|A0A087WWB9|A0A087WWB9_HUMAN" 4 828.4018 0.95 26015 8391 2 828.401153 415.2082 Ras-related protein Rab-3C OS=Homo sapiens OX=9606 GN=RAB3C PE=1 SV=1 6 2044.1 - 1.16E+06 - - - -0.7448 - 1.43 0.287 - 81.7 1 1 0 -0.0006 7 0 0 0 3.14E+08 3.30E+08 - - - 2.2939 0.9872 221125_WJC_METTL3_EV_vs_WT_F03.08396.08396.2 0.000251 16-Sep L.FYTNEEVAK.N "sp|P43243|MATR3_HUMAN,tr|B3KM87|B3KM87_HUMAN,tr|A8MXP9|A8MXP9_HUMAN,tr|A0A0R4J2E8|A0A0R4J2E8_HUMAN" 4 1099.5186 1.26 26018 8396 2 1099.517673 550.7666 Matrin-3 OS=Homo sapiens OX=9606 GN=MATR3 PE=1 SV=2 4.53 2044.6 - 3.43E+06 - - - -0.834 - 1.529 0.524 - 203.2 1 1 0 -0.0009 9 0 0 0 1.41E+08 1.12E+08 - - - 4.1394 0.9996 221125_WJC_METTL3_EV_vs_WT_F03.08401.08401.2 1.76E-06 14-Sep K.MMVAGFK[136.11]K[136.11].Q "sp|Q00839|HNRPU_HUMAN,tr|A0A1W2PQL0|A0A1W2PQL0_HUMAN,tr|A0A1W2PPL4|A0A1W2PPL4_HUMAN,tr|A0A1W2PQ74|A0A1W2PQ74_HUMAN,tr|Q5RI18|Q5RI18_HUMAN,tr|A0A1W2PP35|A0A1W2PP35_HUMAN,tr|A0A1W2PPS1|A0A1W2PPS1_HUMAN,tr|A0A1W2PRZ7|A0A1W2PRZ7_HUMAN,tr|A0A1W2PPH7|A0A1W2PPH7_HUMAN,tr|A0A1W2PQD4|A0A1W2PQD4_HUMAN,tr|A0A1W2PP34|A0A1W2PP34_HUMAN,tr|A0A1X7SBS1|A0A1X7SBS1_HUMAN" 12 926.5053 0.97 26021 8401 2 926.5041 464.2599 Heterogeneous nuclear ribonucleoprotein U OS=Homo sapiens OX=9606 GN=HNRNPU PE=1 SV=6 10 2045.3 - 8.53E+06 - - - -1.2585 - 1.831 0.363 - 352.8 1 2 0 -0.0012 8 0 0 0 3.87E+08 3.97E+08 - - - 3.546 0.9141 221125_WJC_METTL3_EV_vs_WT_F03.08403.08403.2 0.00607 12-Jul E.FFETSAK[136.11].D "sp|Q96E17|RAB3C_HUMAN,sp|P51153|RAB13_HUMAN,sp|P61026|RAB10_HUMAN,tr|A0A087WWB9|A0A087WWB9_HUMAN" 4 836.416 0.95 26023 8403 2 836.414161 419.2153 Ras-related protein Rab-3C OS=Homo sapiens OX=9606 GN=RAB3C PE=1 SV=1 6 2045.5 - 3.49E+06 - - - -2.1628 - 1.387 0.365 - 115.3 1 1 0 -0.0018 7 0 0 0 3.13E+08 3.30E+08 - - - 2.7729 0.9975 221125_WJC_METTL3_EV_vs_WT_F03.08406.08406.2 0.0902 14-Jul R.ELVEGEMK[136.11].E sp|Q15424|SAFB1_HUMAN 1 941.4619 1.63 26024 8406 2 941.460861 471.7382 Scaffold attachment factor B1 OS=Homo sapiens OX=9606 GN=SAFB PE=1 SV=4 4.25 2045.8 - 1.32E+06 - - - -1.1387 - 1.42 0.231 - 174.9 1 2 0 -0.0011 8 0 0 0 5.04E+07 3.09E+07 - - - 1.8044 0.9974 221125_WJC_METTL3_EV_vs_WT_F03.08415.08415.2 0.0354 14-Aug R.LGYLNHVR.A "sp|P51948|MAT1_HUMAN,tr|H0YJ92|H0YJ92_HUMAN" 2 970.5348 1.29 26029 8415 2 970.532548 486.2747 CDK-activating kinase assembly factor MAT1 OS=Homo sapiens OX=9606 GN=MNAT1 PE=1 SV=1 8.75 2047.1 - 1.78E+06 - - - -2.3709 - 1.465 0.305 - 149.9 1 2 0 -0.0023 8 0 0 0 2.55E+07 1.97E+07 - - - 2.4447 0.9644 221125_WJC_METTL3_EV_vs_WT_F03.08419.08419.2 1.34 12-Jul K.LGLHSLR[166.11].H "sp|P84077|ARF1_HUMAN,sp|P61204|ARF3_HUMAN,tr|H0YGG7|H0YGG7_HUMAN" 3 804.4845 1.07 26030 8419 2 804.482501 403.2495 ADP-ribosylation factor 1 OS=Homo sapiens OX=9606 GN=ARF1 PE=1 SV=2 9.76 2047.6 - 4.60E+06 - - - -2.537 - 1.394 0.059 - 167.6 1 2 0 -0.002 7 0 0 0 3.27E+08 3.07E+08 - - - 0.5287 0.9913 221125_WJC_METTL3_EV_vs_WT_F03.08420.08420.2 0.211 12-Aug R.LNQLYER[166.11].A sp|Q9HCS7|SYF1_HUMAN 1 944.4955 49.58 26031 8420 2 944.492635 473.255 Pre-mRNA-splicing factor SYF1 OS=Homo sapiens OX=9606 GN=XAB2 PE=1 SV=2 6 2047.7 - 923853 - - - -3.0344 - 1.516 0.199 - 220.8 1 2 0 -0.0029 7 0 0 0 7.32E+08 1.48E+07 - - - 1.8283 0.9864 221125_WJC_METTL3_EV_vs_WT_F03.08434.08434.2 1.61 12-Aug K.LGLHSLR.H "sp|P84077|ARF1_HUMAN,sp|P61204|ARF3_HUMAN,tr|H0YGG7|H0YGG7_HUMAN" 3 794.4763 1.07 26038 8434 2 794.475044 398.2454 ADP-ribosylation factor 1 OS=Homo sapiens OX=9606 GN=ARF1 PE=1 SV=2 9.76 2049.5 - 8.38E+06 - - - -1.5457 - 1.416 0.079 - 234.4 1 2 0 -0.0012 7 0 0 0 3.27E+08 3.07E+08 - - - 0.7262 0.9997 221125_WJC_METTL3_EV_vs_WT_F03.08438.08438.2 0.000336 18-Nov R.LLEAASVSSK.G sp|P15924|DESP_HUMAN 1 1003.555 3.19 26040 8438 2 1003.553334 502.7848 Desmoplakin OS=Homo sapiens OX=9606 GN=DSP PE=1 SV=3 6 2049.9 - 6.13E+06 - - - -1.6362 - 2.106 0.454 - 262.5 1 2 0 -0.0016 10 0 0 0 1.77E+08 5.57E+07 - - - 4.4727 0.9984 221125_WJC_METTL3_EV_vs_WT_F03.08439.08439.2 0.00187 18-Nov K.IMATPEQVGK[136.11].M "sp|P12956|XRCC6_HUMAN,tr|B1AHC9|B1AHC9_HUMAN" 2 1080.5729 1.13 26041 8439 2 1080.569411 541.2937 X-ray repair cross-complementing protein 6 OS=Homo sapiens OX=9606 GN=XRCC6 PE=1 SV=2 6 2050 - 2.50E+06 - - - -3.2113 - 1.779 0.389 - 395.4 1 2 0 -0.0035 10 0 0 0 2.50E+08 2.22E+08 - - - 3.521 0.9997 221125_WJC_METTL3_EV_vs_WT_F03.08440.08440.2 0.00127 18-Oct K.AVVDAGITTK.L "sp|Q9NZW5|PALS2_HUMAN,tr|B8ZZG1|B8ZZG1_HUMAN" 2 973.5444 0.69 26042 8440 2 973.544746 487.7795 Protein PALS2 OS=Homo sapiens OX=9606 GN=PALS2 PE=1 SV=2 5.88 2050.1 - 1.14E+06 - - - 0.3441 - 1.779 0.413 - 268.2 1 2 0 0.0003 10 0 0 0 8.02E+07 1.16E+08 - - - 3.6992 0.9995 221125_WJC_METTL3_EV_vs_WT_F03.08443.08443.2 0.000908 14-Sep R.QGYGEGFR.W "sp|Q9NR31|SAR1A_HUMAN,sp|Q9Y6B6|SAR1B_HUMAN,tr|H0Y5E8|H0Y5E8_HUMAN,tr|Q9H029|Q9H029_HUMAN" 4 912.409 1.05 26043 8443 2 912.407577 457.2118 GTP-binding protein SAR1a OS=Homo sapiens OX=9606 GN=SAR1A PE=1 SV=1 6 2050.5 - 1.06E+07 - - - -1.5377 - 1.554 0.429 - 288.5 1 2 0 -0.0014 8 0 0 0 2.62E+09 2.50E+09 - - - 3.5387 0.9998 221125_WJC_METTL3_EV_vs_WT_F03.08444.08444.2 0.0587 18-Nov R.LLEAASVSSK[136.11].G sp|P15924|DESP_HUMAN 1 1011.5692 3.19 26044 8444 2 1011.569053 506.7919 Desmoplakin OS=Homo sapiens OX=9606 GN=DSP PE=1 SV=3 6 2050.6 - 1.76E+06 - - - -0.1216 - 2.041 0.383 - 342.7 1 2 0 -0.0001 10 0 0 0 1.77E+08 5.57E+07 - - - 3.8612 0.9991 221125_WJC_METTL3_EV_vs_WT_F03.08445.08445.2 0.00274 14-Sep R.QGYGEGFR[166.11].W "sp|Q9NR31|SAR1A_HUMAN,sp|Q9Y6B6|SAR1B_HUMAN,tr|H0Y5E8|H0Y5E8_HUMAN,tr|Q9H029|Q9H029_HUMAN" 4 922.4172 1.05 26045 8445 2 922.41561 462.2159 GTP-binding protein SAR1a OS=Homo sapiens OX=9606 GN=SAR1A PE=1 SV=1 6 2050.6 - 1.37E+07 - - - -1.7779 - 1.474 0.385 - 273.9 1 2 0 -0.0016 8 0 0 0 2.62E+09 2.50E+09 - - - 3.0542 0.986 221125_WJC_METTL3_EV_vs_WT_F03.08446.08446.2 0.614 12-May R.SMMSYER.S "sp|P18583|SON_HUMAN,tr|H7C1M2|H7C1M2_HUMAN" 2 902.3626 3.9 26046 8446 2 902.361261 452.1886 Protein SON OS=Homo sapiens OX=9606 GN=SON PE=1 SV=4 5.72 2050.7 - 1.18E+06 - - - -1.5105 - 0.953 0.244 - 93.1 1 2 0 -0.0014 7 0 0 0 6.38E+07 1.64E+07 - - - 0.6902 0.9928 221125_WJC_METTL3_EV_vs_WT_F03.08450.08450.2 0.0105 14-Jul K.TIDDLEDK[136.11].L "tr|A0A087WWU8|A0A087WWU8_HUMAN,tr|J3KN67|J3KN67_HUMAN" 2 955.459 1.18 26047 8450 2 955.455279 478.7368 Tropomyosin alpha-3 chain OS=Homo sapiens OX=9606 GN=TPM3 PE=1 SV=1 3.84 2051.3 - 1.20E+06 - - - -3.8495 - 1.245 0.379 - 129.2 1 2 0 -0.0037 8 0 0 0 7.31E+07 6.21E+07 - - - 2.5 0.9393 221125_WJC_METTL3_EV_vs_WT_F03.08451.08451.2 2.92 14-Jun R.LLLNNGAK.M "sp|P15121|ALDR_HUMAN,tr|E9PCX2|E9PCX2_HUMAN,tr|E9PEF9|E9PEF9_HUMAN" 3 841.5022 2.2 26048 8451 2 841.501102 421.7584 Aldo-keto reductase family 1 member B1 OS=Homo sapiens OX=9606 GN=AKR1B1 PE=1 SV=3 8.75 2051.4 - 549839 - - - -1.2478 - 1.059 0.084 - 59.4 3 2 0 -0.001 8 0 0 0 3.73E+07 1.69E+07 - - - -0.3791 0.9524 221125_WJC_METTL3_EV_vs_WT_F03.08455.08455.2 0.186 20-Sep R.VALVGPNGAGK.S sp|Q9UG63|ABCF2_HUMAN 1 981.5607 0.68 26050 8455 2 981.557932 491.7876 ATP-binding cassette sub-family F member 2 OS=Homo sapiens OX=9606 GN=ABCF2 PE=1 SV=2 8.72 2051.9 - 2.05E+06 - - - -2.8506 - 1.651 0.011 - 192.8 1 2 0 -0.0028 11 0 0 0 1.17E+08 1.71E+08 - - - 0.4777 0.9986 221125_WJC_METTL3_EV_vs_WT_F03.08456.08456.2 0.291 14-Jun K.TIDDLEDK.L "tr|A0A087WWU8|A0A087WWU8_HUMAN,tr|J3KN67|J3KN67_HUMAN" 2 947.4448 1.14 26051 8456 2 947.44375 474.7297 Tropomyosin alpha-3 chain OS=Homo sapiens OX=9606 GN=TPM3 PE=1 SV=1 3.84 2052 - 1.62E+06 - - - -1.0629 - 1.077 0.405 - 83.7 1 2 0 -0.001 8 0 0 0 7.21E+07 6.32E+07 - - - 2.2557 0.9886 221125_WJC_METTL3_EV_vs_WT_F03.08459.08459.2 0.0017 14-Aug K.FGDQGGFK[136.11].L sp|P49790|NU153_HUMAN 1 862.4065 1.4 26052 8459 2 862.402728 432.2105 Nuclear pore complex protein Nup153 OS=Homo sapiens OX=9606 GN=NUP153 PE=1 SV=2 5.84 2052.4 - 1.04E+06 - - - -4.3355 - 1.617 0.259 - 133 1 2 0 -0.0037 8 0 0 0 2.61E+08 1.87E+08 - - - 2.4022 0.9916 221125_WJC_METTL3_EV_vs_WT_F03.08462.08462.2 0.0331 16-Jun R.VGGVFHSTC[160.03].- "sp|Q9H7C9|AAMDC_HUMAN,tr|E9PNP3|E9PNP3_HUMAN,tr|E9PR47|E9PR47_HUMAN,tr|E9PIQ4|E9PIQ4_HUMAN" 4 962.428 - 26055 8462 2 962.427281 482.2213 Mth938 domain-containing protein OS=Homo sapiens OX=9606 GN=AAMDC PE=1 SV=1 6.7 2052.6 - 1.30E+06 - - - -0.7481 - 1.084 0.206 - 63.1 1 2 0 -0.0007 9 0 0 0 - - - - - 0.7956 0.9988 221125_WJC_METTL3_EV_vs_WT_F03.08468.08468.2 0.0114 12-Jul K.IDPTLC[160.03]R.A "sp|Q2VIR3|IF2GL_HUMAN,sp|P41091|IF2G_HUMAN" 2 873.4378 0.92 26057 8468 2 873.436532 437.7262 Eukaryotic translation initiation factor 2 subunit 3B OS=Homo sapiens OX=9606 GN=EIF2S3B PE=2 SV=2 5.83 2053.4 - 7.32E+06 - - - -1.4952 - 1.477 0.318 - 239.4 1 2 0 -0.0013 7 0 0 0 2.24E+08 2.45E+08 - - - 2.6251 0.9994 221125_WJC_METTL3_EV_vs_WT_F03.08472.08472.2 0.000785 12-Jun R.MYSYPAR.V "sp|P07910|HNRPC_HUMAN,tr|B4DY08|B4DY08_HUMAN,tr|G3V575|G3V575_HUMAN,tr|G3V5V7|G3V5V7_HUMAN,tr|B2R5W2|B2R5W2_HUMAN,tr|G3V4C1|G3V4C1_HUMAN,tr|G3V576|G3V576_HUMAN,tr|G3V2D6|G3V2D6_HUMAN,tr|G3V4W0|G3V4W0_HUMAN,tr|G3V555|G3V555_HUMAN,tr|G3V2Q1|G3V2Q1_HUMAN" 11 886.4007 1.28 26058 8472 2 886.399893 444.2076 Heterogeneous nuclear ribonucleoproteins C1\C2 OS=Homo sapiens OX=9606 GN=HNRNPC PE=1 SV=4 8.34 2054 - 1.63E+07 - - - -0.9375 - 1.355 0.399 - 184.3 1 2 0 -0.0008 7 0 0 0 1.63E+09 1.28E+09 - - - 2.9504 0.9952 221125_WJC_METTL3_EV_vs_WT_F03.08474.08474.2 0.081 16-Aug K.AITTSLTTK[136.11].W "sp|Q9NYU2|UGGG1_HUMAN,tr|F8WCE6|F8WCE6_HUMAN,tr|F8WCI2|F8WCI2_HUMAN" 3 942.5477 0.25 26060 8474 2 942.549341 472.2811 UDP-glucose:glycoprotein glucosyltransferase 1 OS=Homo sapiens OX=9606 GN=UGGT1 PE=1 SV=3 8.8 2054.2 - 724976 - - - 1.7283 - 1.305 0.246 - 173 1 2 0 0.0016 9 0 0 0 3.60E+07 1.47E+08 - - - 1.6276 0.9992 221125_WJC_METTL3_EV_vs_WT_F03.08478.08478.2 0.00436 18-Sep R.SLETENAGLR.L "sp|P02545|LMNA_HUMAN,tr|A0A6Q8PF80|A0A6Q8PF80_HUMAN,tr|A0A804HL68|A0A804HL68_HUMAN,tr|A0A6Q8PFM1|A0A6Q8PFM1_HUMAN,tr|A0A6Q8PF59|A0A6Q8PF59_HUMAN,tr|A0A6Q8PFJ0|A0A6Q8PFJ0_HUMAN,tr|A0A6Q8PHQ9|A0A6Q8PHQ9_HUMAN,tr|A0A6Q8PGH0|A0A6Q8PGH0_HUMAN,tr|Q3BDU5|Q3BDU5_HUMAN" 9 1088.5462 11.25 26062 8478 2 1088.547755 545.2804 Prelamin-A\C OS=Homo sapiens OX=9606 GN=LMNA PE=1 SV=1 4.53 2054.7 - 883914 - - - 1.4267 - 1.612 0.37 - 232.4 1 2 0 0.0016 10 0 0 0 1.65E+08 1.46E+07 - - - 3.1061 0.9812 221125_WJC_METTL3_EV_vs_WT_F03.08483.08483.2 3.02 12-Jun K.IVSITER.A "sp|Q96KR1|ZFR_HUMAN,sp|Q9BVJ7|DUS23_HUMAN,tr|H0Y8W1|H0Y8W1_HUMAN" 3 816.4705 1.02 26064 8483 2 816.469701 409.2425 Zinc finger RNA-binding protein OS=Homo sapiens OX=9606 GN=ZFR PE=1 SV=2 6 2055.5 - 1.10E+06 - - - -1.0006 - 1.307 0.058 - 101.2 1 2 0 -0.0008 7 0 0 0 4.16E+07 4.08E+07 - - - 0.3175 0.9199 221125_WJC_METTL3_EV_vs_WT_F03.08487.08487.2 0.518 12-May R.IFVNDDR.H "sp|Q12906|ILF3_HUMAN,tr|K7EM82|K7EM82_HUMAN,tr|K7ER69|K7ER69_HUMAN,tr|K7ENK6|K7ENK6_HUMAN,tr|K7EJ09|K7EJ09_HUMAN,tr|K7ERM6|K7ERM6_HUMAN,tr|K7EKJ9|K7EKJ9_HUMAN" 7 877.4294 0.58 26066 8487 2 877.42503 439.722 Interleukin enhancer-binding factor 3 OS=Homo sapiens OX=9606 GN=ILF3 PE=1 SV=3 4.21 2055.9 - 2.27E+06 - - - -4.9588 - 1.23 0.198 - 88.1 1 2 0 -0.0044 7 0 0 0 7.41E+08 1.27E+09 - - - 1.158 0.9985 221125_WJC_METTL3_EV_vs_WT_F03.08488.08488.2 0.0678 16-Aug K.EGLQNMEAR.L "sp|P31948|STIP1_HUMAN,tr|F5GXD8|F5GXD8_HUMAN,tr|F5H783|F5H783_HUMAN" 3 1046.4815 1.07 26067 8488 2 1046.482033 524.248 Stress-induced-phosphoprotein 1 OS=Homo sapiens OX=9606 GN=STIP1 PE=1 SV=1 4.53 2056 - 1.12E+06 - - - 0.516 - 1.324 0.303 - 176.8 1 2 0 0.0005 9 0 0 0 9.01E+07 8.41E+07 - - - 2.0907 0.9988 221125_WJC_METTL3_EV_vs_WT_F03.08489.08489.2 0.0662 12-Jul R.FSGVPDR.F "sp|A0A075B6R9|KVD24_HUMAN,sp|A0A0C4DH68|KV224_HUMAN,sp|A2NJV5|KV229_HUMAN,sp|A0A075B6S2|KVD29_HUMAN,sp|A0A0A0MRZ7|KVD26_HUMAN" 5 776.3817 86.36 26068 8489 2 776.3807 389.1981 Probable non-functional immunoglobulin kappa variable 2D-24 OS=Homo sapiens OX=9606 GN=IGKV2D-24 PE=1 SV=1 5.84 2056.1 - 5.93E+06 - - - -1.2919 - 1.526 0.288 - 155.7 1 2 0 -0.001 7 0 0 0 3.96E+08 4.59E+06 - - - 2.507 0.9904 221125_WJC_METTL3_EV_vs_WT_F03.08496.08496.2 0.0146 12-Jul R.YSQYLDR.Q "sp|Q15020|SART3_HUMAN,tr|A0A499FI31|A0A499FI31_HUMAN" 2 943.4399 0.66 26070 8496 2 943.437852 472.7272 Squamous cell carcinoma antigen recognized by T-cells 3 OS=Homo sapiens OX=9606 GN=SART3 PE=1 SV=1 5.83 2057 - 3.59E+06 - - - -2.2195 - 1.42 0.155 - 164.7 1 2 0 -0.0021 7 0 0 0 1.07E+08 1.64E+08 - - - 1.2962 0.9828 221125_WJC_METTL3_EV_vs_WT_F03.08501.08501.2 0.00111 16-Nov E.LATDPELEK[136.11].K "sp|Q86U44|MTA70_HUMAN,tr|B4E349|B4E349_HUMAN,tr|F5H6D8|F5H6D8_HUMAN,tr|H0YFV6|H0YFV6_HUMAN,tr|B4DTN4|B4DTN4_HUMAN" 5 1022.5375 0.09 26072 8501 2 1022.536228 512.276 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 4.14 2057.6 - 1.37E+06 - - - -1.2841 - 2.052 0.39 - 351.3 1 1 0 -0.0013 9 0 0 0 3.76E+07 4.03E+08 - - - 4.0007 0.9694 221125_WJC_METTL3_EV_vs_WT_F03.08506.08506.2 1.99 14-Jun K.FADGEVVR[166.11].G "sp|Q14739|LBR_HUMAN,tr|A0A494C1L1|A0A494C1L1_HUMAN,tr|C9JES9|C9JES9_HUMAN,tr|C9JXK0|C9JXK0_HUMAN" 4 901.4533 0.9 26075 8506 2 901.455873 451.7339 Delta(14)-sterol reductase LBR OS=Homo sapiens OX=9606 GN=LBR PE=1 SV=2 4.37 2058.2 - 1.36E+06 - - - 2.8532 - 1.354 0.134 - 77.4 2 2 0 0.0026 8 0 0 0 5.02E+07 5.56E+07 - - - 0.8095 0.9944 221125_WJC_METTL3_EV_vs_WT_F03.08509.08509.2 1.24 12-Aug K.TVANMIK[136.11].G "sp|P63208|SKP1_HUMAN,tr|E5RJR5|E5RJR5_HUMAN,tr|E7ERH2|E7ERH2_HUMAN,tr|F8W8N3|F8W8N3_HUMAN" 4 783.4404 0.37 26076 8509 2 783.440053 392.7275 S-phase kinase-associated protein 1 OS=Homo sapiens OX=9606 GN=SKP1 PE=1 SV=2 8.41 2058.6 - 1.77E+06 - - - -0.4557 - 1.479 0.102 - 201.2 1 2 0 -0.0004 7 0 0 0 2.03E+07 5.46E+07 - - - 1.0343 0.9992 221125_WJC_METTL3_EV_vs_WT_F03.08511.08511.2 0.00871 14-Aug R.FSELTAEK[136.11].L "sp|P48643|TCPE_HUMAN,tr|E9PCA1|E9PCA1_HUMAN,tr|B7ZAR1|B7ZAR1_HUMAN,tr|E7ENZ3|E7ENZ3_HUMAN" 4 931.4742 0.66 26077 8511 2 931.472502 466.7444 T-complex protein 1 subunit epsilon OS=Homo sapiens OX=9606 GN=CCT5 PE=1 SV=1 4.53 2058.8 - 5.08E+06 - - - -1.8369 - 1.45 0.422 - 190 1 2 0 -0.0017 8 0 0 0 3.29E+09 5.01E+09 - - - 3.278 0.991 221125_WJC_METTL3_EV_vs_WT_F03.08512.08512.2 0.16 14-Jun K.IILSDEGK[136.11].M "sp|Q15562|TEAD2_HUMAN,sp|P28347|TEAD1_HUMAN,sp|Q15561|TEAD4_HUMAN,sp|Q99594|TEAD3_HUMAN,tr|A0A1X7SBS4|A0A1X7SBS4_HUMAN,tr|Q53GI4|Q53GI4_HUMAN,tr|H0YE88|H0YE88_HUMAN,tr|H0YCZ6|H0YCZ6_HUMAN,tr|H0YGS2|H0YGS2_HUMAN,tr|H0Y7B0|H0Y7B0_HUMAN,tr|H0YEJ9|H0YEJ9_HUMAN,tr|B5MCM0|B5MCM0_HUMAN,tr|A0A0A0MRF3|A0A0A0MRF3_HUMAN,tr|A0A7P0SNI2|A0A7P0SNI2_HUMAN" 14 881.4949 2.08 26078 8512 2 881.493943 441.7548 Transcriptional enhancer factor TEF-4 OS=Homo sapiens OX=9606 GN=TEAD2 PE=1 SV=2 4.37 2058.9 - 2.04E+06 - - - -1.1401 - 1.28 0.145 - 89.7 1 2 0 -0.001 8 0 0 0 1.47E+08 7.09E+07 - - - 0.8562 0.9973 221125_WJC_METTL3_EV_vs_WT_F03.08513.08513.2 0.131 14-Jun K.QTFGYGAR.L "sp|O95433|AHSA1_HUMAN,tr|H0YJU2|H0YJU2_HUMAN,tr|G3V438|G3V438_HUMAN" 3 898.4297 1.04 26079 8513 2 898.429716 450.2221 Activator of 90 kDa heat shock protein ATPase homolog 1 OS=Homo sapiens OX=9606 GN=AHSA1 PE=1 SV=1 8.75 2058.9 - 9.56E+06 - - - 0 - 1.212 0.261 - 138.1 1 2 0 0 8 0 0 0 2.33E+08 2.25E+08 - - - 1.5486 0.9981 221125_WJC_METTL3_EV_vs_WT_F03.08518.08518.2 0.0974 14-Jun K.IILSDEGK.M "sp|Q15562|TEAD2_HUMAN,sp|P28347|TEAD1_HUMAN,sp|Q15561|TEAD4_HUMAN,sp|Q99594|TEAD3_HUMAN,tr|A0A1X7SBS4|A0A1X7SBS4_HUMAN,tr|Q53GI4|Q53GI4_HUMAN,tr|H0YE88|H0YE88_HUMAN,tr|H0YCZ6|H0YCZ6_HUMAN,tr|H0YGS2|H0YGS2_HUMAN,tr|H0Y7B0|H0Y7B0_HUMAN,tr|H0YEJ9|H0YEJ9_HUMAN,tr|B5MCM0|B5MCM0_HUMAN,tr|A0A0A0MRF3|A0A0A0MRF3_HUMAN,tr|A0A7P0SNI2|A0A7P0SNI2_HUMAN" 14 873.4807 1.68 26082 8518 2 873.479952 437.7477 Transcriptional enhancer factor TEF-4 OS=Homo sapiens OX=9606 GN=TEAD2 PE=1 SV=2 4.37 2059.5 - 2.40E+06 - - - -0.9113 - 1.223 0.314 - 88.3 1 2 0 -0.0008 8 0 0 0 1.50E+08 8.91E+07 - - - 1.9671 0.9803 221125_WJC_METTL3_EV_vs_WT_F03.08519.08519.2 0.0853 12-Aug K.ETLPNVR.V sp|Q01658|NC2B_HUMAN 1 827.4501 1.25 26083 8519 2 827.447384 414.7323 Protein Dr1 OS=Homo sapiens OX=9606 GN=DR1 PE=1 SV=1 6.1 2059.6 - 851437 - - - -3.3029 - 1.341 0.186 - 169.9 1 2 0 -0.0027 7 0 0 0 1.03E+08 8.24E+07 - - - 1.3436 0.9997 221125_WJC_METTL3_EV_vs_WT_F03.08520.08520.2 0.00104 12-Aug R.YEDYDYR[166.11].Y sp|Q13595|TRA2A_HUMAN 1 1032.4064 1.54 26084 8520 2 1032.404103 517.2105 Transformer-2 protein homolog alpha OS=Homo sapiens OX=9606 GN=TRA2A PE=1 SV=1 4.03 2059.7 - 1.13E+06 - - - -2.2356 - 1.444 0.663 - 191.2 1 2 0 -0.0023 7 0 0 0 1.50E+08 9.75E+07 - - - 5.1014 0.9998 221125_WJC_METTL3_EV_vs_WT_F03.08521.08521.2 0.0012 16-Sep K.IDVGEAEPR[166.11].T "sp|P54577|SYYC_HUMAN,tr|A0A6Q8PFX2|A0A6Q8PFX2_HUMAN" 2 994.4959 0.79 26085 8521 2 994.495383 498.2552 "Tyrosine--tRNA ligase, cytoplasmic OS=Homo sapiens OX=9606 GN=YARS1 PE=1 SV=4" 4.14 2059.9 - 1.11E+06 - - - -0.5138 - 1.996 0.422 - 260.5 1 2 0 -0.0005 9 0 0 0 1.71E+08 2.17E+08 - - - 4.1573 0.9973 221125_WJC_METTL3_EV_vs_WT_F03.08524.08524.2 0.0607 16-Aug K.MEADGVEVK.R sp|Q13123|RED_HUMAN 1 976.4535 8.93 26086 8524 2 976.451062 489.234 Protein Red OS=Homo sapiens OX=9606 GN=IK PE=1 SV=3 4.14 2060.2 - 1.18E+06 - - - -2.5449 - 1.691 0.266 - 159.8 1 2 0 -0.0025 9 0 0 0 6.94E+07 7.77E+06 - - - 2.5247 0.9992 221125_WJC_METTL3_EV_vs_WT_F03.08529.08529.2 0.0157 14-Sep R.YFDPANGK[136.11].F sp|P13639|EF2_HUMAN 1 918.4327 0.48 26088 8529 2 918.43105 460.2236 Elongation factor 2 OS=Homo sapiens OX=9606 GN=EEF2 PE=1 SV=4 5.83 2060.8 - 1.55E+07 - - - -1.7769 - 1.639 0.362 - 203.1 1 2 0 -0.0016 8 0 0 0 2.68E+08 5.62E+08 - - - 3.2044 0.9995 221125_WJC_METTL3_EV_vs_WT_F03.08531.08531.2 0.0199 16-Oct K.IDVGEAEPR.T "sp|P54577|SYYC_HUMAN,tr|A0A6Q8PFX2|A0A6Q8PFX2_HUMAN" 2 984.4876 0.78 26090 8531 2 984.488723 493.2511 "Tyrosine--tRNA ligase, cytoplasmic OS=Homo sapiens OX=9606 GN=YARS1 PE=1 SV=4" 4.14 2061.1 - 1.42E+06 - - - 1.1163 - 1.916 0.32 - 293.5 1 2 0 0.0011 9 0 0 0 1.71E+08 2.18E+08 - - - 3.2854 0.997 221125_WJC_METTL3_EV_vs_WT_F03.08537.08537.2 0.204 12-Jul R.EEVSSWR.R sp|Q14152|EIF3A_HUMAN 1 891.4086 1.05 26092 8537 2 891.408426 446.7116 Eukaryotic translation initiation factor 3 subunit A OS=Homo sapiens OX=9606 GN=EIF3A PE=1 SV=1 4.53 2061.9 - 1.83E+06 - - - -0.2468 - 1.233 0.241 - 188.5 1 2 0 -0.0002 7 0 0 0 7.21E+07 6.88E+07 - - - 1.4846 0.9976 221125_WJC_METTL3_EV_vs_WT_F03.08538.08538.2 0.00778 18-Sep R.SLETENAGLR[166.11].L "sp|P02545|LMNA_HUMAN,tr|A0A6Q8PF80|A0A6Q8PF80_HUMAN,tr|A0A804HL68|A0A804HL68_HUMAN,tr|A0A6Q8PFM1|A0A6Q8PFM1_HUMAN,tr|A0A6Q8PF59|A0A6Q8PF59_HUMAN,tr|A0A6Q8PFJ0|A0A6Q8PFJ0_HUMAN,tr|A0A6Q8PHQ9|A0A6Q8PHQ9_HUMAN,tr|A0A6Q8PGH0|A0A6Q8PGH0_HUMAN,tr|Q3BDU5|Q3BDU5_HUMAN" 9 1098.5545 11.32 26093 8538 2 1098.551593 550.2845 Prelamin-A\C OS=Homo sapiens OX=9606 GN=LMNA PE=1 SV=1 4.53 2062 - 1.16E+06 - - - -2.6207 - 1.482 0.345 - 210.1 1 2 0 -0.0029 10 0 0 0 1.66E+08 1.46E+07 - - - 2.6863 0.999 221125_WJC_METTL3_EV_vs_WT_F03.08543.08543.2 0.000321 14-Sep R.YFDPANGK.F sp|P13639|EF2_HUMAN 1 910.4185 0.48 26096 8543 2 910.41679 456.2165 Elongation factor 2 OS=Homo sapiens OX=9606 GN=EEF2 PE=1 SV=4 5.83 2062.6 - 6.89E+06 - - - -1.8585 - 1.489 0.377 - 198.9 1 2 0 -0.0017 8 0 0 0 2.69E+08 5.62E+08 - - - 3.0257 0.9967 221125_WJC_METTL3_EV_vs_WT_F03.08545.08545.2 0.07 12-Jun R.EEVSSWR[166.11].R sp|Q14152|EIF3A_HUMAN 1 901.4169 1.06 26098 8545 2 901.415238 451.7157 Eukaryotic translation initiation factor 3 subunit A OS=Homo sapiens OX=9606 GN=EIF3A PE=1 SV=1 4.53 2062.7 - 1.19E+06 - - - -1.8615 - 1.327 0.269 - 149 1 2 0 -0.0017 7 0 0 0 7.40E+07 7.01E+07 - - - 1.9238 0.9993 221125_WJC_METTL3_EV_vs_WT_F03.08548.08548.2 0.0632 14-Sep R.LAAELEDR.R "sp|Q9NQG5|RPR1B_HUMAN,tr|A2A2M0|A2A2M0_HUMAN,tr|A0A087X2D2|A0A087X2D2_HUMAN" 3 915.4662 0.68 26099 8548 2 915.464557 458.7404 Regulation of nuclear pre-mRNA domain-containing protein 1B OS=Homo sapiens OX=9606 GN=RPRD1B PE=1 SV=1 4.14 2063.1 - 1.05E+07 - - - -1.7521 - 2.085 0.281 - 289.4 1 2 0 -0.0016 8 0 0 0 3.54E+08 5.19E+08 - - - 3.332 0.8881 221125_WJC_METTL3_EV_vs_WT_F03.08549.08549.2 0.127 12-May R.EIAQDFK.T "sp|Q16695|H31T_HUMAN,sp|P84243|H33_HUMAN,sp|Q71DI3|H32_HUMAN,sp|P68431|H31_HUMAN,tr|B4DEB1|B4DEB1_HUMAN,tr|K7EK07|K7EK07_HUMAN,tr|K7ES00|K7ES00_HUMAN,tr|K7EMV3|K7EMV3_HUMAN,tr|A0A590UJJ6|A0A590UJJ6_HUMAN" 9 849.4232 0.93 26100 8549 2 849.422061 425.7189 Histone H3.1t OS=Homo sapiens OX=9606 GN=H3-4 PE=1 SV=3 4.37 2063.1 - 4.37E+06 - - - -1.3798 - 1.08 0.014 - 131.2 2 2 0 -0.0012 7 0 0 0 4.89E+09 5.23E+09 - - - -0.7466 0.986 221125_WJC_METTL3_EV_vs_WT_F03.08553.08553.2 0.0954 12-Jul R.AVDFAER[166.11].H "sp|P62917|RL8_HUMAN,tr|G3V1A1|G3V1A1_HUMAN,tr|E9PKZ0|E9PKZ0_HUMAN,tr|E9PP36|E9PP36_HUMAN,tr|E9PKU4|E9PKU4_HUMAN" 5 816.4005 0.95 26102 8553 2 816.398956 409.2075 60S ribosomal protein L8 OS=Homo sapiens OX=9606 GN=RPL8 PE=1 SV=2 4.37 2063.7 - 1.07E+07 - - - -1.9365 - 1.324 0.129 - 193.4 1 2 0 -0.0016 7 0 0 0 3.79E+08 3.97E+08 - - - 0.8826 0.9994 221125_WJC_METTL3_EV_vs_WT_F03.08563.08563.2 0.000593 16-Sep R.VLNTNIDGR.R "sp|P62269|RS18_HUMAN,tr|A0A0G2JQH2|A0A0G2JQH2_HUMAN,tr|Q5GGW2|Q5GGW2_HUMAN" 3 1000.5302 0.99 26106 8563 2 1000.528595 501.2724 40S ribosomal protein S18 OS=Homo sapiens OX=9606 GN=RPS18 PE=1 SV=3 5.81 2064.9 - 5.68E+07 - - - -1.5622 - 2.065 0.291 - 308.8 1 2 0 -0.0016 9 0 0 0 2.58E+09 2.62E+09 - - - 3.2877 0.9993 221125_WJC_METTL3_EV_vs_WT_F03.08564.08564.2 0.0161 16-Aug K.NLSVEDAAR.L sp|P04040|CATA_HUMAN 1 973.4829 1.6 26107 8564 2 973.482503 487.7487 Catalase OS=Homo sapiens OX=9606 GN=CAT PE=1 SV=3 4.37 2064.9 - 2.39E+06 - - - -0.3801 - 1.56 0.315 - 189.8 1 2 0 -0.0004 9 0 0 0 6.86E+07 4.30E+07 - - - 2.654 0.9995 221125_WJC_METTL3_EV_vs_WT_F03.08568.08568.2 0.0065 14-Aug R.FSELTAEK.L "sp|P48643|TCPE_HUMAN,tr|E9PCA1|E9PCA1_HUMAN,tr|B7ZAR1|B7ZAR1_HUMAN,tr|E7ENZ3|E7ENZ3_HUMAN" 4 923.46 0.66 26109 8568 2 923.458709 462.7373 T-complex protein 1 subunit epsilon OS=Homo sapiens OX=9606 GN=CCT5 PE=1 SV=1 4.53 2065.4 - 1.08E+08 - - - -1.4121 - 1.766 0.373 - 155.5 1 2 0 -0.0013 8 0 0 0 3.29E+09 5.01E+09 - - - 3.5108 0.9997 221125_WJC_METTL3_EV_vs_WT_F03.08569.08569.2 0.00113 18-Dec K.LGSLVENNER[166.11].V "sp|Q99613|EIF3C_HUMAN,sp|B5ME19|EIFCL_HUMAN" 2 1139.581 0.3 26110 8569 2 1139.578484 570.7978 Eukaryotic translation initiation factor 3 subunit C OS=Homo sapiens OX=9606 GN=EIF3C PE=1 SV=1 4.53 2065.4 - 5.61E+06 - - - -2.2263 - 2.631 0.436 - 668.1 1 2 0 -0.0025 10 0 0 0 6.25E+07 2.05E+08 - - - 4.9607 0.8465 221125_WJC_METTL3_EV_vs_WT_F03.08570.08570.2 0.304 12-Jul Y.GNVVELR[166.11].L "sp|Q13283|G3BP1_HUMAN,sp|Q9UN86|G3BP2_HUMAN,tr|A0A7I2YQF2|A0A7I2YQF2_HUMAN,tr|A0A7I2V5M7|A0A7I2V5M7_HUMAN,tr|A0A7I2V647|A0A7I2V647_HUMAN,tr|A0A7I2V5H1|A0A7I2V5H1_HUMAN,tr|A0A7I2YQD9|A0A7I2YQD9_HUMAN,tr|A0A7I2V382|A0A7I2V382_HUMAN,tr|A0A7I2V565|A0A7I2V565_HUMAN,tr|A0A7I2YQN9|A0A7I2YQN9_HUMAN,tr|A0A7I2YQH0|A0A7I2YQH0_HUMAN,tr|A0A7I2V3P9|A0A7I2V3P9_HUMAN,tr|A0A7I2V494|A0A7I2V494_HUMAN" 13 795.4478 1.34 26111 8570 2 795.446545 398.7312 Ras GTPase-activating protein-binding protein 1 OS=Homo sapiens OX=9606 GN=G3BP1 PE=1 SV=1 6 2065.5 - 1.64E+06 - - - -1.6054 - 1.51 0.206 - 342 1 1 0 -0.0013 7 0 0 0 2.16E+08 1.61E+08 - - - 1.8679 0.9973 221125_WJC_METTL3_EV_vs_WT_F03.08579.08579.2 9.76 18-Aug K.LVNTINPGAR.F sp|Q92900|RENT1_HUMAN 1 1053.5931 1.05 26115 8579 2 1053.590915 527.8038 Regulator of nonsense transcripts 1 OS=Homo sapiens OX=9606 GN=UPF1 PE=1 SV=2 9.75 2066.6 - 405220 - - - -2.0672 - 1.445 0.291 - 220.2 1 2 0 -0.0022 10 0 0 0 9.45E+07 8.97E+07 - - - 2.2171 0.9987 221125_WJC_METTL3_EV_vs_WT_F03.08580.08580.2 0.000771 18-Sep K.LVNTINPGAR[166.11].F sp|Q92900|RENT1_HUMAN 1 1063.6014 1.05 26116 8580 2 1063.599527 532.808 Regulator of nonsense transcripts 1 OS=Homo sapiens OX=9606 GN=UPF1 PE=1 SV=2 9.75 2066.7 - 751754 - - - -1.7262 - 1.54 0.327 - 186.6 1 2 0 -0.0018 10 0 0 0 9.45E+07 8.97E+07 - - - 2.6609 0.9991 221125_WJC_METTL3_EV_vs_WT_F03.08585.08585.2 0.0229 14-Aug R.SPDTILQK[136.11].D sp|P20042|IF2B_HUMAN 1 908.5058 0.86 26119 8585 2 908.504894 455.2602 Eukaryotic translation initiation factor 2 subunit 2 OS=Homo sapiens OX=9606 GN=EIF2S2 PE=1 SV=2 5.55 2067.3 - 1.37E+06 - - - -1.049 - 1.635 0.281 - 237.3 1 2 0 -0.001 8 0 0 0 1.40E+08 1.63E+08 - - - 2.5989 0.999 221125_WJC_METTL3_EV_vs_WT_F03.08592.08592.2 0.0316 14-Aug R.IIDEVVNK[136.11].F sp|O95816|BAG2_HUMAN 1 936.5371 0.22 26123 8592 2 936.535907 469.2758 BAG family molecular chaperone regulator 2 OS=Homo sapiens OX=9606 GN=BAG2 PE=1 SV=1 4.37 2068.1 - 2.20E+06 - - - -1.324 - 1.591 0.301 - 132.9 1 2 0 -0.0012 8 0 0 0 6.00E+07 2.73E+08 - - - 2.6643 0.7819 221125_WJC_METTL3_EV_vs_WT_F03.08594.08594.2 3.01 12-Jun E.ADLDITK.R "sp|Q9BZW7|TSG10_HUMAN,sp|P62269|RS18_HUMAN,tr|B8ZZZ9|B8ZZZ9_HUMAN,tr|F8WA32|F8WA32_HUMAN,tr|A0A669KBL0|A0A669KBL0_HUMAN" 5 774.4123 0.95 26124 8594 2 774.411707 388.2134 Testis-specific gene 10 protein OS=Homo sapiens OX=9606 GN=TSGA10 PE=1 SV=1 4.21 2068.3 - 1.27E+07 - - - -0.8096 - 1.327 0.176 - 197.7 1 1 0 -0.0006 7 0 0 0 4.86E+08 5.09E+08 - - - 1.2372 0.9994 221125_WJC_METTL3_EV_vs_WT_F03.08596.08596.2 0.0185 16-Jun K.VVLVESSER.L "sp|P50336|PPOX_HUMAN,tr|A0A494C0M9|A0A494C0M9_HUMAN,tr|A0A1W2PPA5|A0A1W2PPA5_HUMAN,tr|A0A1W2PNH4|A0A1W2PNH4_HUMAN,tr|A0A494C146|A0A494C146_HUMAN,tr|A0A1W2PRF9|A0A1W2PRF9_HUMAN,tr|A0A494C0L4|A0A494C0L4_HUMAN,tr|A0A494C0D4|A0A494C0D4_HUMAN,tr|F5GZT7|F5GZT7_HUMAN,tr|D3DVG2|D3DVG2_HUMAN,tr|F5H1I5|F5H1I5_HUMAN" 11 1016.5502 0.91 26125 8596 2 1016.549841 509.2824 Protoporphyrinogen oxidase OS=Homo sapiens OX=9606 GN=PPOX PE=1 SV=1 4.53 2068.5 - 927354 - - - -0.3777 - 1.476 0.369 - 114.9 1 2 0 -0.0004 9 0 0 0 3.93E+07 4.32E+07 - - - 2.8927 0.9982 221125_WJC_METTL3_EV_vs_WT_F03.08599.08599.2 0.0627 16-Jun R.SPPLATGYR[166.11].Y sp|Q86U06|RBM23_HUMAN 1 970.5112 1.84 26128 8599 2 970.510464 486.2629 Probable RNA-binding protein 23 OS=Homo sapiens OX=9606 GN=RBM23 PE=1 SV=1 8.46 2068.7 - 1.86E+06 - - - -0.7079 - 1.618 0.201 - 122.7 1 2 0 -0.0007 9 0 0 0 2.32E+08 1.26E+08 - - - 1.9175 0.9993 221125_WJC_METTL3_EV_vs_WT_F03.08603.08603.2 0.0215 14-Aug R.SPDTILQK.D sp|P20042|IF2B_HUMAN 1 900.4916 0.88 26130 8603 2 900.491166 451.2531 Eukaryotic translation initiation factor 2 subunit 2 OS=Homo sapiens OX=9606 GN=EIF2S2 PE=1 SV=2 5.55 2069.2 - 2.94E+06 - - - -0.5342 - 1.648 0.294 - 244.2 1 2 0 -0.0005 8 0 0 0 1.40E+08 1.59E+08 - - - 2.719 0.9996 221125_WJC_METTL3_EV_vs_WT_F03.08606.08606.2 0.0539 16-Aug R.SPPLATGYR.Y sp|Q86U06|RBM23_HUMAN 1 960.5029 1.88 26132 8606 2 960.502174 481.2587 Probable RNA-binding protein 23 OS=Homo sapiens OX=9606 GN=RBM23 PE=1 SV=1 8.46 2069.6 - 2.55E+06 - - - -0.7361 - 1.771 0.369 - 213 1 2 0 -0.0007 9 0 0 0 2.45E+08 1.30E+08 - - - 3.4197 0.9997 221125_WJC_METTL3_EV_vs_WT_F03.08614.08614.2 0.00315 16-Jul K.DVDGAYMTK.V sp|P04264|K2C1_HUMAN 1 998.4379 8182.1 26137 8614 2 998.437052 500.2262 "Keratin, type II cytoskeletal 1 OS=Homo sapiens OX=9606 GN=KRT1 PE=1 SV=6" 4.21 2070.5 - 3.02E+06 - - - -0.8463 - 1.38 0.512 - 80.2 1 2 0 -0.0008 9 0 0 0 1.79E+10 2.19E+06 - - - 3.7542 0.9998 221125_WJC_METTL3_EV_vs_WT_F03.08622.08622.2 0.000393 20-Sep R.VLEAVSANPGR[166.11].F sp|Q9NXH9|TRM1_HUMAN 1 1121.6068 0.92 26142 8622 2 1121.607352 561.8107 tRNA (guanine(26)-N(2))-dimethyltransferase OS=Homo sapiens OX=9606 GN=TRMT1 PE=1 SV=1 5.97 2071.4 - 323628 - - - 0.4547 - 1.945 0.44 - 172.7 1 2 0 0.0005 11 0 0 0 7.93E+06 8.58E+06 - - - 4.0904 0.997 221125_WJC_METTL3_EV_vs_WT_F03.08625.08625.2 0.0413 16-Sep K.LSDIGVEDK[136.11].S sp|Q96F45|ZN503_HUMAN 1 982.5062 1.45 26143 8625 2 982.50233 492.2604 Zinc finger protein 503 OS=Homo sapiens OX=9606 GN=ZNF503 PE=1 SV=1 4.03 2071.8 - 5.75E+06 - - - -3.9806 - 1.896 0.349 - 197.9 1 2 0 -0.0039 9 0 0 0 2.18E+09 1.50E+09 - - - 3.4683 0.9969 221125_WJC_METTL3_EV_vs_WT_F03.08626.08626.2 0.306 14-Aug K.MNSIVYQK[136.11].Q "sp|Q9Y520|PRC2C_HUMAN,tr|E7EPN9|E7EPN9_HUMAN,tr|A0A2R8Y424|A0A2R8Y424_HUMAN,tr|H7C5N8|H7C5N8_HUMAN,tr|A0A2R8Y7F4|A0A2R8Y7F4_HUMAN,tr|A0A2R8YET2|A0A2R8YET2_HUMAN" 6 989.5096 17.48 26144 8626 2 989.508533 495.7621 Protein PRRC2C OS=Homo sapiens OX=9606 GN=PRRC2C PE=1 SV=4 8.34 2071.8 - 1.77E+06 - - - -1.0298 - 1.559 0.166 - 212.9 1 2 0 -0.001 8 0 0 0 9.86E+08 5.64E+07 - - - 1.606 0.9901 221125_WJC_METTL3_EV_vs_WT_F03.08630.08630.2 1.01 12-Jul R.ADILEDK.D "sp|P52272|HNRPM_HUMAN,tr|M0R019|M0R019_HUMAN,tr|M0R0N3|M0R0N3_HUMAN,tr|A0A087X0X3|A0A087X0X3_HUMAN,tr|M0QZM1|M0QZM1_HUMAN,tr|M0QYQ7|M0QYQ7_HUMAN,tr|M0R2T0|M0R2T0_HUMAN" 7 802.4072 1.82 26146 8630 2 802.406685 402.2109 Heterogeneous nuclear ribonucleoprotein M OS=Homo sapiens OX=9606 GN=HNRNPM PE=1 SV=3 4.03 2072.3 - 1.12E+07 - - - -0.7029 - 1.671 0.001 - 197.4 1 2 0 -0.0006 7 0 0 0 3.61E+08 1.98E+08 - - - 0.675 0.9919 221125_WJC_METTL3_EV_vs_WT_F03.08634.08634.2 0.159 16-Aug K.GVVPGGGLK[136.11].A "sp|O75822|EIF3J_HUMAN,tr|H0YLP3|H0YLP3_HUMAN" 2 790.4792 0.46 26148 8634 2 790.478088 396.2469 Eukaryotic translation initiation factor 3 subunit J OS=Homo sapiens OX=9606 GN=EIF3J PE=1 SV=2 8.75 2072.7 - 1.40E+06 - - - -1.4548 - 1.078 0.243 - 158.2 1 2 0 -0.0012 9 0 0 0 3.28E+07 7.10E+07 - - - 1.0527 0.9991 221125_WJC_METTL3_EV_vs_WT_F03.08636.08636.2 0.00407 16-Sep R.ISAVSVAER.V sp|Q08211|DHX9_HUMAN 1 930.5134 0.76 26150 8636 2 930.51307 466.264 ATP-dependent RNA helicase A OS=Homo sapiens OX=9606 GN=DHX9 PE=1 SV=4 6 2072.9 - 8.09E+06 - - - -0.403 - 1.895 0.213 - 240 1 2 0 -0.0004 9 0 0 0 4.67E+08 6.13E+08 - - - 2.4634 0.9979 221125_WJC_METTL3_EV_vs_WT_F03.08637.08637.2 0.152 12-Jul K.IYEISNR.W sp|Q01780|EXOSX_HUMAN 1 893.4607 0.92 26151 8637 2 893.460304 447.7376 Exosome component 10 OS=Homo sapiens OX=9606 GN=EXOSC10 PE=1 SV=2 6 2073 - 2.77E+06 - - - -0.422 - 1.409 0.222 - 185 1 2 0 -0.0004 7 0 0 0 6.85E+07 7.46E+07 - - - 1.767 0.9319 221125_WJC_METTL3_EV_vs_WT_F03.08638.08638.2 4.37 12-Jul R.QELQELR.R "sp|Q9BUZ4|TRAF4_HUMAN,sp|Q9Y250|LZTS1_HUMAN,sp|Q6XUX3|DUSTY_HUMAN,tr|F6SA91|F6SA91_HUMAN" 4 914.4821 4.21 26152 8638 2 914.480053 458.2483 TNF receptor-associated factor 4 OS=Homo sapiens OX=9606 GN=TRAF4 PE=1 SV=1 4.53 2073.1 - 494007 - - - -2.2876 - 1.195 0.049 - 164.4 1 2 0 -0.0021 7 0 0 0 2.49E+07 5.91E+06 - - - -0.0333 0.9747 221125_WJC_METTL3_EV_vs_WT_F03.08650.08650.2 0.405 12-Aug R.MQAQWER.E "sp|Q15424|SAFB1_HUMAN,tr|K7EII0|K7EII0_HUMAN" 2 947.4283 1.51 26158 8650 2 947.422367 474.7214 Scaffold attachment factor B1 OS=Homo sapiens OX=9606 GN=SAFB PE=1 SV=4 5.75 2074.5 - 2.15E+06 - - - -6.2992 - 1.774 0.282 - 288.8 1 2 0 -0.006 7 0 0 0 5.50E+07 3.64E+07 - - - 2.9383 0.9946 221125_WJC_METTL3_EV_vs_WT_F03.08652.08652.2 0.179 16-May R.LIPDGC[160.03]GVK.Y "sp|P27635|RL10_HUMAN,sp|Q96L21|RL10L_HUMAN,tr|F8W7C6|F8W7C6_HUMAN,tr|X1WI28|X1WI28_HUMAN" 4 957.4954 0.89 26159 8652 2 957.4942 479.755 60S ribosomal protein L10 OS=Homo sapiens OX=9606 GN=RPL10 PE=1 SV=4 5.83 2074.7 - 3.27E+06 - - - -1.2042 - 0.914 0.333 - 71.4 1 2 0 -0.0012 9 0 0 0 4.64E+08 5.19E+08 - - - 1.24 0.9949 221125_WJC_METTL3_EV_vs_WT_F03.08659.08659.2 0.009 16-Sep R.LGEYEDVSR.V "sp|Q99426|TBCB_HUMAN,tr|A0A494C0X0|A0A494C0X0_HUMAN,tr|K7EP07|K7EP07_HUMAN,tr|K7EL99|K7EL99_HUMAN,tr|K7EK42|K7EK42_HUMAN" 5 1066.4931 0.73 26163 8659 2 1066.490803 534.2538 Tubulin-folding cofactor B OS=Homo sapiens OX=9606 GN=TBCB PE=1 SV=2 4.14 2075.6 - 3.67E+06 - - - -2.1575 - 1.186 0.299 - 190.6 1 2 0 -0.0023 9 0 0 0 2.90E+07 3.97E+07 - - - 1.7422 0.9912 221125_WJC_METTL3_EV_vs_WT_F03.08660.08660.2 0.00603 18-Sep R.YLAEVASGEK.K "sp|Q04917|1433F_HUMAN,tr|A2IDB2|A2IDB2_HUMAN" 2 1065.5342 1.05 26164 8660 2 1065.537334 533.7744 14-3-3 protein eta OS=Homo sapiens OX=9606 GN=YWHAH PE=1 SV=4 4.53 2075.6 - 3.67E+06 - - - 2.9037 - 1.304 0.269 - 199 1 2 0 0.0031 10 0 0 0 8.31E+07 7.90E+07 - - - 1.7678 0.9999 221125_WJC_METTL3_EV_vs_WT_F03.08671.08671.2 0.000196 18-Dec R.YPDGIISK[136.11]PK[136.11].N sp|Q86U44|MTA70_HUMAN 1 1132.6463 0.02 26169 8671 2 1132.645032 567.3304 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 8.5 2077 - 3.59E+06 - - - -1.1283 - 2.168 0.536 - 528.1 1 2 0 -0.0013 10 0 0 0 4.00E+06 2.00E+08 - - - 5.1594 0.9268 221125_WJC_METTL3_EV_vs_WT_F03.08674.08674.2 3.39 14-Jun R.LWQEEQER.K "sp|Q53GS7|GLE1_HUMAN,tr|A0A804HI94|A0A804HI94_HUMAN,tr|A0A804HK09|A0A804HK09_HUMAN,tr|A0A804HJB3|A0A804HJB3_HUMAN,tr|A0A804HJY9|A0A804HJY9_HUMAN,tr|A0A804HIJ1|A0A804HIJ1_HUMAN,tr|A0A804HJ70|A0A804HJ70_HUMAN" 7 1116.52 1.43 26172 8674 2 1116.516421 559.2673 mRNA export factor GLE1 OS=Homo sapiens OX=9606 GN=GLE1 PE=1 SV=2 4.25 2077.2 - 496326 - - - -3.1939 - 1.135 0.125 - 115.8 1 2 0 -0.0036 8 0 0 0 1.15E+07 8.07E+06 - - - 0.345 0.9986 221125_WJC_METTL3_EV_vs_WT_F03.08684.08684.2 0.246 14-Sep K.LTDTLVSK[136.11].Q sp|Q86UP2|KTN1_HUMAN 1 883.5106 2 26177 8684 2 883.509758 442.7626 Kinectin OS=Homo sapiens OX=9606 GN=KTN1 PE=1 SV=1 5.84 2078.4 - 2.33E+06 - - - -0.9508 - 1.847 0.182 - 209.9 1 2 0 -0.0008 8 0 0 0 2.05E+08 1.02E+08 - - - 2.2355 0.9999 221125_WJC_METTL3_EV_vs_WT_F03.08689.08689.3 0.000115 Nov-36 K.LTPEQLHSMR.Q "sp|Q9Y2R0|COA3_HUMAN,tr|K7EPV0|K7EPV0_HUMAN" 2 1210.6128 1.44 26178 8689 3 1210.611255 404.5449 "Cytochrome c oxidase assembly factor 3 homolog, mitochondrial OS=Homo sapiens OX=9606 GN=COA3 PE=1 SV=1" 6.75 2079.1 - 3.99E+06 - - - -1.3109 - 2.179 0.447 - 203 1 2 0 -0.0016 10 0 0 0 2.02E+08 1.41E+08 - - - 5.7978 0.9975 221125_WJC_METTL3_EV_vs_WT_F03.08696.08696.2 0.00461 16-Aug R.TLLEGEESR.M sp|P04264|K2C1_HUMAN 1 1032.5088 1801.51 26182 8696 2 1032.511762 517.2617 "Keratin, type II cytoskeletal 1 OS=Homo sapiens OX=9606 GN=KRT1 PE=1 SV=6" 4.25 2079.8 - 3.79E+06 - - - 2.9133 - 1.458 0.37 - 183.1 1 2 0 0.003 9 0 0 0 6.11E+10 3.39E+07 - - - 2.8637 0.9997 221125_WJC_METTL3_EV_vs_WT_F03.08700.08700.2 0.00622 14-Sep K.IC[160.03]AVGITK.L sp|P55060|XPO2_HUMAN 1 860.479 0.91 26185 8700 2 860.478139 431.2468 Exportin-2 OS=Homo sapiens OX=9606 GN=CSE1L PE=1 SV=3 8.22 2080.1 - 2.11E+06 - - - -0.9704 - 1.722 0.398 - 175.9 1 2 0 -0.0008 8 0 0 0 1.57E+08 1.73E+08 - - - 3.6195 0.9978 221125_WJC_METTL3_EV_vs_WT_F03.08707.08707.2 0.000316 18-Oct R.YVSAQPLAGR.Q "sp|Q9BSJ2|GCP2_HUMAN,tr|A0A804HJH7|A0A804HJH7_HUMAN,tr|F2Z2B9|F2Z2B9_HUMAN,tr|A0A804HK74|A0A804HK74_HUMAN,tr|A0A804HL95|A0A804HL95_HUMAN,tr|A0A804HJ08|A0A804HJ08_HUMAN,tr|A0A804HJQ4|A0A804HJQ4_HUMAN,tr|A0A804HJS9|A0A804HJS9_HUMAN,tr|A0A804HI27|A0A804HI27_HUMAN" 9 1060.5665 1.86 26189 8707 2 1060.563047 531.2905 Gamma-tubulin complex component 2 OS=Homo sapiens OX=9606 GN=TUBGCP2 PE=1 SV=2 8.75 2081 - 649751 - - - -3.2964 - 1.684 0.373 - 286.5 1 2 0 -0.0035 10 0 0 0 5.48E+07 2.95E+07 - - - 3.2496 0.9634 221125_WJC_METTL3_EV_vs_WT_F03.08709.08709.2 0.469 12-May K.GLPVYNK.S sp|Q9BW61|DDA1_HUMAN 1 789.4385 1.01 26191 8709 2 789.439344 395.7265 DET1- and DDB1-associated protein 1 OS=Homo sapiens OX=9606 GN=DDA1 PE=1 SV=1 8.59 2081.1 - 2.75E+06 - - - 1.083 - 1.056 0.12 - 114.2 2 2 0 0.0009 7 0 0 0 1.49E+08 1.47E+08 - - - -0.0348 0.9985 221125_WJC_METTL3_EV_vs_WT_F03.08715.08715.2 0.747 14-Aug K.INEEISVK[136.11].H "sp|Q9BUJ2|HNRL1_HUMAN,tr|M0QYZ0|M0QYZ0_HUMAN,tr|A0A0A0MRA5|A0A0A0MRA5_HUMAN,tr|M0R3F1|M0R3F1_HUMAN,tr|B7Z4B8|B7Z4B8_HUMAN,tr|M0QYI8|M0QYI8_HUMAN,tr|M0QYM5|M0QYM5_HUMAN" 7 938.5164 1.43 26193 8715 2 938.515384 470.2655 Heterogeneous nuclear ribonucleoprotein U-like protein 1 OS=Homo sapiens OX=9606 GN=HNRNPUL1 PE=1 SV=2 4.53 2081.9 - 6.52E+06 - - - -1.0953 - 1.715 0.208 - 155.7 1 2 0 -0.001 8 0 0 0 7.92E+08 5.55E+08 - - - 2.2038 0.9925 221125_WJC_METTL3_EV_vs_WT_F03.08716.08716.2 0.162 12-Aug R.TPQEYLR.R "sp|O14893|GEMI2_HUMAN,tr|A0A3B3IU42|A0A3B3IU42_HUMAN,tr|G5EA29|G5EA29_HUMAN,tr|H0YDP6|H0YDP6_HUMAN,tr|H0YEL0|H0YEL0_HUMAN" 5 905.4607 0.87 26194 8716 2 905.458252 453.7376 Gem-associated protein 2 OS=Homo sapiens OX=9606 GN=GEMIN2 PE=1 SV=1 5.66 2082 - 938544 - - - -2.6826 - 1.408 0.219 - 230.9 1 2 0 -0.0024 7 0 0 0 1.25E+08 1.44E+08 - - - 1.742 0.9917 221125_WJC_METTL3_EV_vs_WT_F03.08725.08725.2 0.466 14-Aug K.LYEQLSGK[136.11].- sp|P30086|PEBP1_HUMAN 1 944.5058 1.44 26198 8725 2 944.503857 473.2602 Phosphatidylethanolamine-binding protein 1 OS=Homo sapiens OX=9606 GN=PEBP1 PE=1 SV=3 6 2083.1 - 1.95E+06 - - - -2.1069 - 1.46 0.157 - 196.9 1 2 0 -0.002 8 0 0 0 1.04E+08 7.22E+07 - - - 1.3413 0.9969 221125_WJC_METTL3_EV_vs_WT_F03.08726.08726.2 0.5 14-Jun R.TTVVAQLK.Q "sp|P60228|EIF3E_HUMAN,tr|A0A7I2V3I2|A0A7I2V3I2_HUMAN,tr|A0A7I2V570|A0A7I2V570_HUMAN,tr|A0A7I2V2Q9|A0A7I2V2Q9_HUMAN,tr|H0YBP5|H0YBP5_HUMAN,tr|A0A7I2V5Z6|A0A7I2V5Z6_HUMAN,tr|A0A7I2V2H9|A0A7I2V2H9_HUMAN,tr|B3KW56|B3KW56_HUMAN,tr|A0A7I2V4B4|A0A7I2V4B4_HUMAN,tr|A0A7I2V3I0|A0A7I2V3I0_HUMAN,tr|A0A7I2V3S3|A0A7I2V3S3_HUMAN,tr|A0A7I2V4G3|A0A7I2V4G3_HUMAN,tr|A0A7I2V3W9|A0A7I2V3W9_HUMAN,tr|H0YBR5|H0YBR5_HUMAN,tr|A0A7I2V429|A0A7I2V429_HUMAN,tr|A0A7I2V2W0|A0A7I2V2W0_HUMAN,tr|A0A161SXE1|A0A161SXE1_HUMAN" 17 858.5175 1.02 26199 8726 2 858.516316 430.266 Eukaryotic translation initiation factor 3 subunit E OS=Homo sapiens OX=9606 GN=EIF3E PE=1 SV=1 8.41 2083.1 - 4.00E+06 - - - -1.3418 - 1.372 0.235 - 137.4 1 2 0 -0.0012 8 0 0 0 2.40E+08 2.35E+08 - - - 1.7302 0.9746 221125_WJC_METTL3_EV_vs_WT_F03.08727.08727.2 2.06 16-Jul R.ALSTPVVEK[136.11].R "sp|P29084|T2EB_HUMAN,tr|E5RK24|E5RK24_HUMAN,tr|E5RIW4|E5RIW4_HUMAN,tr|E5RH41|E5RH41_HUMAN" 4 950.5528 0.83 26200 8727 2 950.552878 476.2837 Transcription initiation factor IIE subunit beta OS=Homo sapiens OX=9606 GN=GTF2E2 PE=1 SV=1 6.05 2083.3 - 1.16E+06 - - - 0.0852 - 1.1 0.093 - 111.7 1 2 0 0.0001 9 0 0 0 2.98E+07 3.59E+07 - - - 0.0036 0.9983 221125_WJC_METTL3_EV_vs_WT_F03.08730.08730.2 0.0229 14-Aug R.TTVVAQLK[136.11].Q "sp|P60228|EIF3E_HUMAN,tr|A0A7I2V3I2|A0A7I2V3I2_HUMAN,tr|A0A7I2V570|A0A7I2V570_HUMAN,tr|A0A7I2V2Q9|A0A7I2V2Q9_HUMAN,tr|H0YBP5|H0YBP5_HUMAN,tr|A0A7I2V5Z6|A0A7I2V5Z6_HUMAN,tr|A0A7I2V2H9|A0A7I2V2H9_HUMAN,tr|B3KW56|B3KW56_HUMAN,tr|A0A7I2V4B4|A0A7I2V4B4_HUMAN,tr|A0A7I2V3I0|A0A7I2V3I0_HUMAN,tr|A0A7I2V3S3|A0A7I2V3S3_HUMAN,tr|A0A7I2V4G3|A0A7I2V4G3_HUMAN,tr|A0A7I2V3W9|A0A7I2V3W9_HUMAN,tr|H0YBR5|H0YBR5_HUMAN,tr|A0A7I2V429|A0A7I2V429_HUMAN,tr|A0A7I2V2W0|A0A7I2V2W0_HUMAN,tr|A0A161SXE1|A0A161SXE1_HUMAN" 17 866.5317 1.02 26201 8730 2 866.530854 434.2731 Eukaryotic translation initiation factor 3 subunit E OS=Homo sapiens OX=9606 GN=EIF3E PE=1 SV=1 8.41 2083.7 - 6.19E+06 - - - -0.9394 - 1.587 0.216 - 306.5 1 2 0 -0.0008 8 0 0 0 2.40E+08 2.35E+08 - - - 2.029 0.9996 221125_WJC_METTL3_EV_vs_WT_F03.08745.08745.2 0.00223 16-Aug K.EFTEAVEAK.Q "sp|P35232|PHB_HUMAN,tr|C9JZ20|C9JZ20_HUMAN,tr|E7ESE2|E7ESE2_HUMAN,tr|E9PCW0|E9PCW0_HUMAN,tr|C9JW96|C9JW96_HUMAN" 5 1022.492 0.01 26205 8745 2 1022.49177 512.2533 Prohibitin OS=Homo sapiens OX=9606 GN=PHB PE=1 SV=1 4.25 2085.8 - 3.13E+06 - - - -0.265 - 1.603 0.394 - 314 1 2 0 -0.0003 9 0 0 0 5.41E+08 5.25E+10 - - - 3.3162 0.9951 221125_WJC_METTL3_EV_vs_WT_F03.08750.08750.2 0.00211 18-Aug K.FVGQDVEGER.M "sp|P17812|PYRG1_HUMAN,tr|B4E1E0|B4E1E0_HUMAN,tr|A0A3B3IRI2|A0A3B3IRI2_HUMAN" 3 1134.5306 0.29 26208 8750 2 1134.528477 568.2726 CTP synthase 1 OS=Homo sapiens OX=9606 GN=CTPS1 PE=1 SV=2 4.14 2086.4 - 2.06E+06 - - - -1.829 - 1.547 0.181 - 146.1 1 2 0 -0.0021 10 0 0 0 8.56E+07 2.98E+08 - - - 1.5951 0.9062 221125_WJC_METTL3_EV_vs_WT_F03.08761.08761.2 0.179 16-Sep K.LVQLGQAEK[136.11].R "sp|O75208|COQ9_HUMAN,tr|H3BPY0|H3BPY0_HUMAN,tr|H3BNT2|H3BNT2_HUMAN" 3 992.5746 1.19 26215 8761 2 992.570203 497.2946 "Ubiquinone biosynthesis protein COQ9, mitochondrial OS=Homo sapiens OX=9606 GN=COQ9 PE=1 SV=1" 6 2087.8 - 1.63E+06 - - - -4.4249 - 1.578 0.055 - 258.7 1 2 0 -0.0044 9 0 0 0 8.77E+07 7.37E+07 - - - 0.7655 0.9713 221125_WJC_METTL3_EV_vs_WT_F03.08762.08762.2 0.204 14-Aug K.C[160.03]IIVEEGK.E "sp|P60981|DEST_HUMAN,tr|F6RFD5|F6RFD5_HUMAN" 2 946.4794 2.56 26216 8762 2 946.477587 474.247 Destrin OS=Homo sapiens OX=9606 GN=DSTN PE=1 SV=3 4.53 2087.9 - 926847 - - - -1.8817 - 1.266 0.083 - 206.5 1 2 0 -0.0018 8 0 0 0 6.50E+07 2.54E+07 - - - 0.3648 0.9993 221125_WJC_METTL3_EV_vs_WT_F03.08763.08763.2 0.232 14-Sep R.QQLLEEER.T sp|Q9NSI2|SLX9_HUMAN 1 1043.5247 1.72 26217 8763 2 1043.5253 522.7696 Ribosome biogenesis protein SLX9 homolog OS=Homo sapiens OX=9606 GN=SLX9 PE=1 SV=2 4.25 2088 - 678944 - - - 0.5386 - 1.791 0.267 - 413.4 1 2 0 0.0006 8 0 0 0 6.14E+07 3.57E+07 - - - 2.7705 0.9825 221125_WJC_METTL3_EV_vs_WT_F03.08770.08770.2 0.533 12-Jul K.NAEIALR.T "sp|Q9BVL2|NUP58_HUMAN,tr|H7BYF2|H7BYF2_HUMAN,tr|Q5JRG1|Q5JRG1_HUMAN" 3 785.4396 0.89 26220 8770 2 785.438184 393.7271 Nucleoporin p58\p45 OS=Homo sapiens OX=9606 GN=NUP58 PE=1 SV=1 6 2088.8 - 4.95E+06 - - - -1.7417 - 1.648 0.002 - 248.8 1 2 0 -0.0014 7 0 0 0 3.22E+08 3.61E+08 - - - 0.6382 0.9982 221125_WJC_METTL3_EV_vs_WT_F03.08771.08771.2 0.634 16-Sep K.LVQLGQAEK.R "sp|O75208|COQ9_HUMAN,tr|H3BPY0|H3BPY0_HUMAN,tr|H3BNT2|H3BNT2_HUMAN" 3 984.5604 1.2 26221 8771 2 984.560123 493.2875 "Ubiquinone biosynthesis protein COQ9, mitochondrial OS=Homo sapiens OX=9606 GN=COQ9 PE=1 SV=1" 6 2088.9 - 2.39E+06 - - - -0.2763 - 1.621 0.195 - 179.4 1 2 0 -0.0003 9 0 0 0 8.76E+07 7.31E+07 - - - 1.8787 0.9636 221125_WJC_METTL3_EV_vs_WT_F03.08772.08772.2 6.55 14-May K.YAMEQSIK[136.11].S "sp|Q9UHX1|PUF60_HUMAN,tr|A0A0J9YYL3|A0A0J9YYL3_HUMAN,tr|A0A0J9YWM1|A0A0J9YWM1_HUMAN,tr|H0YEM1|H0YEM1_HUMAN,tr|E9PMU7|E9PMU7_HUMAN,tr|E9PN18|E9PN18_HUMAN,tr|E9PL19|E9PL19_HUMAN,tr|A0A0J9YVR6|A0A0J9YVR6_HUMAN,tr|A0A0J9YXX5|A0A0J9YXX5_HUMAN,tr|A0A0J9YXJ8|A0A0J9YXJ8_HUMAN,tr|E9PQ56|E9PQ56_HUMAN,tr|A0A0J9YVP6|A0A0J9YVP6_HUMAN" 12 976.4779 1.31 26222 8772 2 976.477312 489.2462 Poly(U)-binding-splicing factor PUF60 OS=Homo sapiens OX=9606 GN=PUF60 PE=1 SV=1 6 2089 - 4.09E+06 - - - -0.6206 - 1.04 0.087 - 72.1 1 2 0 -0.0006 8 0 0 0 9.19E+07 7.02E+07 - - - -0.1983 0.9513 221125_WJC_METTL3_EV_vs_WT_F03.08775.08775.2 0.000831 16-Jun K.GGGHVAQIY.A "sp|P62249|RS16_HUMAN,tr|M0R210|M0R210_HUMAN,tr|M0R3H0|M0R3H0_HUMAN,tr|M0QX76|M0QX76_HUMAN,tr|M0R1M5|M0R1M5_HUMAN,tr|Q6IPX4|Q6IPX4_HUMAN" 6 900.4454 - 26223 8775 2 900.446579 451.23 40S ribosomal protein S16 OS=Homo sapiens OX=9606 GN=RPS16 PE=1 SV=2 6.74 2089.4 - 4.21E+06 - - - 1.3471 - 1.519 0.365 - 94.7 1 1 0 0.0012 9 0 0 0 - - - - - 2.946 0.9994 221125_WJC_METTL3_EV_vs_WT_F03.08777.08777.2 0.000333 16-Aug M.APAEILNGK[136.11].E "sp|P11586|C1TC_HUMAN,tr|F5H2F4|F5H2F4_HUMAN,tr|V9GYY3|V9GYY3_HUMAN" 3 919.5218 1.3 26224 8777 2 919.521057 460.7682 "C-1-tetrahydrofolate synthase, cytoplasmic OS=Homo sapiens OX=9606 GN=MTHFD1 PE=1 SV=4" 6.05 2089.6 - 2.01E+06 - - - -0.8428 - 1.599 0.351 - 202.6 1 2 0 -0.0008 9 0 0 0 2.25E+08 1.72E+08 - - - 2.9912 0.9904 221125_WJC_METTL3_EV_vs_WT_F03.08779.08779.2 0.0796 12-Jul K.LPTISQR.L sp|Q15388|TOM20_HUMAN 1 813.4709 1.37 26225 8779 2 813.469686 407.7427 Mitochondrial import receptor subunit TOM20 homolog OS=Homo sapiens OX=9606 GN=TOMM20 PE=1 SV=1 9.75 2089.8 - 7.47E+06 - - - -1.4334 - 1.428 0.102 - 160.7 1 2 0 -0.0012 7 0 0 0 7.47E+08 5.46E+08 - - - 0.9229 0.7743 221125_WJC_METTL3_EV_vs_WT_F03.08780.08780.2 1.79 12-Aug L.LEGEESR.L "sp|P08670|VIME_HUMAN,sp|Q9NSB2|KRT84_HUMAN,sp|P17661|DESM_HUMAN,sp|P05787|K2C8_HUMAN,sp|P41219|PERI_HUMAN,sp|Q7Z794|K2C1B_HUMAN,sp|P04264|K2C1_HUMAN,sp|P08729|K2C7_HUMAN,tr|H7C5W5|H7C5W5_HUMAN,tr|B0YJC5|B0YJC5_HUMAN,tr|B0YJC4|B0YJC4_HUMAN" 11 818.377 22.64 26226 8780 2 818.375547 410.1958 Vimentin OS=Homo sapiens OX=9606 GN=VIM PE=1 SV=4 4.25 2089.8 - 4.34E+06 - - - -1.7889 - 1.702 0.117 - 219.4 1 1 0 -0.0015 7 0 0 0 1.32E+08 5.81E+06 - - - 1.5898 0.9996 221125_WJC_METTL3_EV_vs_WT_F03.08781.08781.2 0.00616 18-Oct K.LAQAYYESTR.K sp|P20930|FILA_HUMAN 1 1200.5775 3198.57 26227 8781 2 1200.575172 601.296 Filaggrin OS=Homo sapiens OX=9606 GN=FLG PE=1 SV=3 6 2090 - 2.67E+06 - - - -1.9407 - 2.275 0.375 - 531.7 1 2 0 -0.0023 10 0 0 0 2.35E+08 7.36E+04 - - - 4.1044 0.935 221125_WJC_METTL3_EV_vs_WT_F03.08782.08782.2 0.529 12-Jun K.FLPNAPK[136.11].A "sp|Q92499|DDX1_HUMAN,tr|A0A7I2V2M5|A0A7I2V2M5_HUMAN,tr|A0A087X2G1|A0A087X2G1_HUMAN,tr|A0A7I2V430|A0A7I2V430_HUMAN,tr|A0A7I2V421|A0A7I2V421_HUMAN,tr|A0A7I2V4F0|A0A7I2V4F0_HUMAN,tr|A0A7I2V5X8|A0A7I2V5X8_HUMAN,tr|A0A7I2V4J3|A0A7I2V4J3_HUMAN,tr|A0A087WZ71|A0A087WZ71_HUMAN,tr|A0A7I2YQ77|A0A7I2YQ77_HUMAN" 10 793.4578 12.15 26228 8782 2 793.454826 397.7362 ATP-dependent RNA helicase DDX1 OS=Homo sapiens OX=9606 GN=DDX1 PE=1 SV=2 8.75 2090 - 1.37E+06 - - - -3.7166 - 1.107 0.179 - 102.8 1 2 0 -0.0029 7 0 0 0 3.49E+08 2.87E+07 - - - 0.6843 0.9956 221125_WJC_METTL3_EV_vs_WT_F03.08789.08789.2 0.0337 12-Aug K.LPTISQR[166.11].L sp|Q15388|TOM20_HUMAN 1 823.4791 1.39 26232 8789 2 823.477061 412.7468 Mitochondrial import receptor subunit TOM20 homolog OS=Homo sapiens OX=9606 GN=TOMM20 PE=1 SV=1 9.75 2090.9 - 4.33E+06 - - - -2.5028 - 1.516 0.231 - 255.1 1 2 0 -0.0021 7 0 0 0 7.44E+08 5.34E+08 - - - 2.0649 0.9995 221125_WJC_METTL3_EV_vs_WT_F03.08791.08791.2 0.00338 16-Sep M.APAEILNGK.E "sp|P11586|C1TC_HUMAN,tr|F5H2F4|F5H2F4_HUMAN,tr|V9GYY3|V9GYY3_HUMAN" 3 911.5076 0.89 26233 8791 2 911.508456 456.7611 "C-1-tetrahydrofolate synthase, cytoplasmic OS=Homo sapiens OX=9606 GN=MTHFD1 PE=1 SV=4" 6.05 2091.1 - 5.65E+06 - - - 0.904 - 1.547 0.412 - 254.4 1 2 0 0.0008 9 0 0 0 2.48E+08 2.79E+08 - - - 3.3461 0.9994 221125_WJC_METTL3_EV_vs_WT_F03.08796.08796.2 0.00191 18-Dec R.LAAMANNLQK[136.11].G "sp|Q86U06|RBM23_HUMAN,tr|H0YJJ3|H0YJJ3_HUMAN,tr|G3XAP0|G3XAP0_HUMAN,tr|G3V546|G3V546_HUMAN" 4 1080.5841 1.56 26236 8796 2 1080.584672 541.2993 Probable RNA-binding protein 23 OS=Homo sapiens OX=9606 GN=RBM23 PE=1 SV=1 8.75 2091.7 - 1.70E+06 - - - 0.5164 - 2.271 0.215 - 428.4 1 2 0 0.0006 10 0 0 0 1.54E+08 9.91E+07 - - - 2.9183 0.997 221125_WJC_METTL3_EV_vs_WT_F03.08801.08801.2 0.11 14-Jun K.LLEGEESR.L "sp|P08670|VIME_HUMAN,sp|Q9NSB2|KRT84_HUMAN,sp|P17661|DESM_HUMAN,sp|P05787|K2C8_HUMAN,sp|P41219|PERI_HUMAN,sp|Q7Z794|K2C1B_HUMAN,sp|P04264|K2C1_HUMAN,sp|P08729|K2C7_HUMAN,tr|H7C5W5|H7C5W5_HUMAN,tr|B0YJC5|B0YJC5_HUMAN,tr|B0YJC4|B0YJC4_HUMAN" 11 931.4611 1.28 26238 8801 2 931.459666 466.7378 Vimentin OS=Homo sapiens OX=9606 GN=VIM PE=1 SV=4 4.25 2092.3 - 2.35E+06 - - - -1.5127 - 1.189 0.308 - 68.5 1 2 0 -0.0014 8 0 0 0 7.76E+07 6.06E+07 - - - 1.8375 0.9949 221125_WJC_METTL3_EV_vs_WT_F03.08806.08806.2 0.14 16-Sep K.GLAPEVADR.L "sp|P49590|SYHM_HUMAN,sp|P12081|HARS1_HUMAN,tr|A0A6Q8PF47|A0A6Q8PF47_HUMAN,tr|A0A2R8Y5P7|A0A2R8Y5P7_HUMAN,tr|A0A6Q8PF07|A0A6Q8PF07_HUMAN,tr|B4E1C5|B4E1C5_HUMAN,tr|A0A2R8Y6I1|A0A2R8Y6I1_HUMAN,tr|B4DQ67|B4DQ67_HUMAN,tr|A0A6Q8PHA5|A0A6Q8PHA5_HUMAN,tr|E7ETE2|E7ETE2_HUMAN,tr|D6RB22|D6RB22_HUMAN,tr|A0A2R8Y3N3|A0A2R8Y3N3_HUMAN,tr|A0A6Q8PFF2|A0A6Q8PFF2_HUMAN,tr|A0A6Q8PHE3|A0A6Q8PHE3_HUMAN,tr|B4DDD8|B4DDD8_HUMAN,tr|D6RJE6|D6RJE6_HUMAN" 16 926.4821 0.71 26242 8806 2 926.485019 464.2483 "Histidine--tRNA ligase, mitochondrial OS=Homo sapiens OX=9606 GN=HARS2 PE=1 SV=1" 4.37 2092.7 - 1.90E+06 - - - 3.1021 - 1.704 0.237 - 360.7 1 2 0 0.0029 9 0 0 0 9.68E+07 1.37E+08 - - - 2.3325 0.9556 221125_WJC_METTL3_EV_vs_WT_F03.08808.08808.2 4.32 12-Jul K.QAFEQIK.K "sp|Q14683|SMC1A_HUMAN,tr|G8JLG1|G8JLG1_HUMAN,tr|A0A6Q8PHC3|A0A6Q8PHC3_HUMAN,tr|V9GY57|V9GY57_HUMAN" 4 862.4549 1.61 26244 8808 2 862.453395 432.2347 Structural maintenance of chromosomes protein 1A OS=Homo sapiens OX=9606 GN=SMC1A PE=1 SV=2 6 2093 - 969690 - - - -1.7079 - 1.204 0.05 - 156.7 1 2 0 -0.0015 7 0 0 0 3.65E+07 2.27E+07 - - - -0.0019 0.9999 221125_WJC_METTL3_EV_vs_WT_F03.08809.08809.2 2.34E-06 13/18 R.VLNTEANVVR.K sp|O00391|QSOX1_HUMAN 1 1113.6142 999 26245 8809 2 1113.613725 557.8144 Sulfhydryl oxidase 1 OS=Homo sapiens OX=9606 GN=QSOX1 PE=1 SV=3 5.97 2093.1 - 844795 - - - -0.4463 - 2.576 0.492 - 742.4 1 2 0 -0.0005 10 0 0 0 1.82E+07 0.00E+00 - - - 5.316 0.9998 221125_WJC_METTL3_EV_vs_WT_F03.08812.08812.2 0.00223 18-Nov R.LAAMANNLQK.G "sp|Q86U06|RBM23_HUMAN,tr|H0YJJ3|H0YJJ3_HUMAN,tr|G3XAP0|G3XAP0_HUMAN,tr|G3V546|G3V546_HUMAN" 4 1072.5699 1.56 26246 8812 2 1072.56871 537.2922 Probable RNA-binding protein 23 OS=Homo sapiens OX=9606 GN=RBM23 PE=1 SV=1 8.75 2093.5 - 5.84E+06 - - - -1.1225 - 2.309 0.381 - 428 1 2 0 -0.0012 10 0 0 0 1.54E+08 9.91E+07 - - - 4.1905 0.9976 221125_WJC_METTL3_EV_vs_WT_F03.08813.08813.2 0.328 12-Sep K.YQLAVTK.V "sp|Q8NDV3|SMC1B_HUMAN,sp|Q14683|SMC1A_HUMAN,tr|G8JLG1|G8JLG1_HUMAN,tr|F8VV13|F8VV13_HUMAN,tr|A0A6Q8PHC3|A0A6Q8PHC3_HUMAN" 5 821.4647 5.29 26247 8813 2 821.462836 411.7396 Structural maintenance of chromosomes protein 1B OS=Homo sapiens OX=9606 GN=SMC1B PE=2 SV=2 8.59 2093.6 - 4.05E+06 - - - -2.274 - 1.677 0.239 - 257.4 1 2 0 -0.0019 7 0 0 0 6.00E+08 1.13E+08 - - - 2.4438 0.8918 221125_WJC_METTL3_EV_vs_WT_F03.08814.08814.2 0.0297 20-Jul S.LQAEEEPMLER[166.11].R tr|C9JYJ8|C9JYJ8_HUMAN 1 1353.6474 0.62 26248 8814 2 1353.64838 677.831 Replication initiator 1 (Fragment) OS=Homo sapiens OX=9606 GN=REPIN1 PE=1 SV=8 4.09 2093.7 - 1.30E+06 - - - 0.7343 - 1.46 0.251 - 93.5 1 1 0 0.001 11 0 0 0 3.96E+07 6.40E+07 - - - 1.9183 0.997 221125_WJC_METTL3_EV_vs_WT_F03.08815.08815.2 0.289 14-Sep R.TITSSYYR[166.11].G "sp|Q9H0U4|RAB1B_HUMAN,sp|P62820|RAB1A_HUMAN,sp|Q92928|RAB1C_HUMAN,tr|E7END7|E7END7_HUMAN" 4 999.4901 1.29 26249 8815 2 999.488746 500.7523 Ras-related protein Rab-1B OS=Homo sapiens OX=9606 GN=RAB1B PE=1 SV=1 8.25 2093.8 - 986864 - - - -1.3357 - 1.383 0.235 - 238.2 1 2 0 -0.0013 8 0 0 0 5.75E+08 4.47E+08 - - - 1.7542 0.9983 221125_WJC_METTL3_EV_vs_WT_F03.08819.08819.2 0.168 14-Jun K.EFSGNPIK.V "sp|P35637|FUS_HUMAN,tr|H3BPE7|H3BPE7_HUMAN" 2 890.4498 1.05 26251 8819 2 890.448487 446.2322 RNA-binding protein FUS OS=Homo sapiens OX=9606 GN=FUS PE=1 SV=1 6.1 2094.4 - 8.56E+06 - - - -1.4543 - 1.322 0.321 - 180.8 1 2 0 -0.0013 8 0 0 0 3.35E+09 3.18E+09 - - - 2.2534 0.9973 221125_WJC_METTL3_EV_vs_WT_F03.08820.08820.2 0.213 12-Jun R.SAFLSQR.Y "sp|P35658|NU214_HUMAN,tr|A0A0A0MSW3|A0A0A0MSW3_HUMAN,tr|A0A494C1F2|A0A494C1F2_HUMAN" 3 807.4239 2.11 26252 8820 2 807.422647 404.7192 Nuclear pore complex protein Nup214 OS=Homo sapiens OX=9606 GN=NUP214 PE=1 SV=2 9.47 2094.4 - 5.76E+06 - - - -1.5543 - 1.322 0.27 - 159.6 1 2 0 -0.0013 7 0 0 0 3.57E+08 1.69E+08 - - - 1.9193 0.9993 221125_WJC_METTL3_EV_vs_WT_F03.08821.08821.2 0.00596 12-Jun K.ILDYSDK.Q sp|Q9H9A6|LRC40_HUMAN 1 852.4229 2.78 26253 8821 2 852.423116 427.2187 Leucine-rich repeat-containing protein 40 OS=Homo sapiens OX=9606 GN=LRRC40 PE=1 SV=1 4.21 2094.5 - 2.27E+06 - - - 0.2546 - 1.367 0.359 - 89.9 1 2 0 0.0002 7 0 0 0 6.37E+07 2.29E+07 - - - 2.6831 0.9971 221125_WJC_METTL3_EV_vs_WT_F03.08826.08826.2 0.0646 14-Jul R.TITSSYYR.G "sp|Q9H0U4|RAB1B_HUMAN,sp|P62820|RAB1A_HUMAN,sp|Q92928|RAB1C_HUMAN,tr|E7END7|E7END7_HUMAN" 4 989.4818 1.29 26256 8826 2 989.482623 495.7482 Ras-related protein Rab-1B OS=Homo sapiens OX=9606 GN=RAB1B PE=1 SV=1 8.25 2095.1 - 2.86E+06 - - - 0.8206 - 1.061 0.33 - 120.1 1 2 0 0.0008 8 0 0 0 5.76E+08 4.47E+08 - - - 1.6567 0.999 221125_WJC_METTL3_EV_vs_WT_F03.08827.08827.2 0.127 16-Oct R.ALADTENLR[166.11].Q sp|Q9HAV7|GRPE1_HUMAN 1 1011.5224 0.93 26257 8827 2 1011.52346 506.7685 "GrpE protein homolog 1, mitochondrial OS=Homo sapiens OX=9606 GN=GRPEL1 PE=1 SV=2" 4.37 2095.1 - 1.97E+06 - - - 1.0044 - 1.773 0.26 - 431.9 1 2 0 0.001 9 0 0 0 7.20E+07 7.77E+07 - - - 2.6178 0.9998 221125_WJC_METTL3_EV_vs_WT_F03.08830.08830.2 0.000301 16-Oct K.LDVGNAEVK[136.11].L "sp|P51572|BAP31_HUMAN,tr|C9J0M4|C9J0M4_HUMAN,tr|C9JQ75|C9JQ75_HUMAN,tr|C9JSP1|C9JSP1_HUMAN,tr|C9JMD7|C9JMD7_HUMAN" 5 951.5117 1 26258 8830 2 951.510611 476.7631 B-cell receptor-associated protein 31 OS=Homo sapiens OX=9606 GN=BCAP31 PE=1 SV=3 4.37 2095.5 - 7.07E+06 - - - -1.1035 - 2.218 0.394 - 274.9 1 2 0 -0.001 9 0 0 0 2.45E+08 2.45E+08 - - - 4.2554 0.9528 221125_WJC_METTL3_EV_vs_WT_F03.08841.08841.2 3.74 12-May K.DLSQQIR[166.11].V sp|P12270|TPR_HUMAN 1 868.4642 1.52 26267 8841 2 868.464317 435.2394 Nucleoprotein TPR OS=Homo sapiens OX=9606 GN=TPR PE=1 SV=3 5.84 2096.7 - 1.22E+06 - - - 0.1347 - 1.195 0.029 - 89.8 3 2 0 0.0001 7 0 0 0 4.90E+07 3.22E+07 - - - -0.3935 0.9967 221125_WJC_METTL3_EV_vs_WT_F03.08842.08842.2 1.57 16-Jul K.GLAPEVADR[166.11].L "sp|P49590|SYHM_HUMAN,sp|P12081|HARS1_HUMAN,tr|A0A6Q8PF47|A0A6Q8PF47_HUMAN,tr|A0A2R8Y5P7|A0A2R8Y5P7_HUMAN,tr|A0A6Q8PF07|A0A6Q8PF07_HUMAN,tr|B4E1C5|B4E1C5_HUMAN,tr|A0A2R8Y6I1|A0A2R8Y6I1_HUMAN,tr|B4DQ67|B4DQ67_HUMAN,tr|A0A6Q8PHA5|A0A6Q8PHA5_HUMAN,tr|E7ETE2|E7ETE2_HUMAN,tr|D6RB22|D6RB22_HUMAN,tr|A0A2R8Y3N3|A0A2R8Y3N3_HUMAN,tr|A0A6Q8PFF2|A0A6Q8PFF2_HUMAN,tr|A0A6Q8PHE3|A0A6Q8PHE3_HUMAN,tr|B4DDD8|B4DDD8_HUMAN,tr|D6RJE6|D6RJE6_HUMAN" 16 936.4904 0.69 26268 8842 2 936.490806 469.2525 "Histidine--tRNA ligase, mitochondrial OS=Homo sapiens OX=9606 GN=HARS2 PE=1 SV=1" 4.37 2096.7 - 970582 - - - 0.4175 - 1.362 0.207 - 140.9 1 2 0 0.0004 9 0 0 0 9.70E+07 1.40E+08 - - - 1.4636 0.999 221125_WJC_METTL3_EV_vs_WT_F03.08845.08845.2 0.00182 14-Jul R.EDMAALEK[136.11].D "sp|Q71U36|TBA1A_HUMAN,sp|P68366|TBA4A_HUMAN,sp|P68363|TBA1B_HUMAN,sp|Q9BQE3|TBA1C_HUMAN,tr|F5H5D3|F5H5D3_HUMAN" 5 913.4306 1.35 26269 8845 2 913.429369 457.7226 Tubulin alpha-1A chain OS=Homo sapiens OX=9606 GN=TUBA1A PE=1 SV=1 4.14 2097.1 - 5.96E+06 - - - -1.3838 - 1.482 0.334 - 229.7 1 2 0 -0.0013 8 0 0 0 3.59E+08 2.65E+08 - - - 2.694 0.9997 221125_WJC_METTL3_EV_vs_WT_F03.08851.08851.2 0.000654 16-Sep K.LDVGNAEVK.L "sp|P51572|BAP31_HUMAN,tr|C9J0M4|C9J0M4_HUMAN,tr|C9JQ75|C9JQ75_HUMAN,tr|C9JSP1|C9JSP1_HUMAN,tr|C9JMD7|C9JMD7_HUMAN" 5 943.4975 1 26273 8851 2 943.497785 472.756 B-cell receptor-associated protein 31 OS=Homo sapiens OX=9606 GN=BCAP31 PE=1 SV=3 4.37 2097.9 - 1.14E+07 - - - 0.3434 - 1.812 0.378 - 222.6 1 2 0 0.0003 9 0 0 0 2.44E+08 2.45E+08 - - - 3.5525 0.983 221125_WJC_METTL3_EV_vs_WT_F03.08853.08853.2 0.111 12-Jun K.VQSQYFR.G sp|Q4VCS5|AMOT_HUMAN 1 926.461 1.33 26275 8853 2 926.457073 464.2378 Angiomotin OS=Homo sapiens OX=9606 GN=AMOT PE=1 SV=1 8.72 2098.1 - 1.49E+06 - - - -4.256 - 1.536 0.217 - 137.9 1 2 0 -0.0039 7 0 0 0 4.00E+07 3.01E+07 - - - 2.0024 0.9736 221125_WJC_METTL3_EV_vs_WT_F03.08857.08857.2 5.04 12-May R.FSGVPDR.F "sp|A0A075B6R9|KVD24_HUMAN,sp|A0A0C4DH68|KV224_HUMAN,sp|A2NJV5|KV229_HUMAN,sp|A0A075B6S2|KVD29_HUMAN,sp|A0A0A0MRZ7|KVD26_HUMAN" 5 776.3817 441.92 26277 8857 2 776.381243 389.1981 Probable non-functional immunoglobulin kappa variable 2D-24 OS=Homo sapiens OX=9606 GN=IGKV2D-24 PE=1 SV=1 5.84 2098.6 - 2.94E+06 - - - -0.5925 - 1.105 0.106 - 75.9 2 2 0 -0.0005 7 0 0 0 5.85E+08 1.32E+06 - - - 0.0057 0.9977 221125_WJC_METTL3_EV_vs_WT_F03.08858.08858.2 0.701 12-Jun K.LQEYLGK.F sp|Q6PKG0|LARP1_HUMAN 1 849.4596 1.69 26278 8858 2 849.459995 425.7371 La-related protein 1 OS=Homo sapiens OX=9606 GN=LARP1 PE=1 SV=2 6 2098.6 - 1.71E+06 - - - 0.4426 - 1.394 0.223 - 109.4 1 2 0 0.0004 7 0 0 0 1.21E+08 7.16E+07 - - - 1.7405 0.85 221125_WJC_METTL3_EV_vs_WT_F03.08859.08859.2 0.212 14-Jun A.ENTQEELR.E "sp|Q9NXR1|NDE1_HUMAN,tr|I3L522|I3L522_HUMAN,tr|I3L2S8|I3L2S8_HUMAN,tr|A0A6Q8PEY3|A0A6Q8PEY3_HUMAN,tr|I3L3G9|I3L3G9_HUMAN,tr|A0A6Q8PHH1|A0A6Q8PHH1_HUMAN,tr|A0A6Q8PGV6|A0A6Q8PGV6_HUMAN,tr|A0A0J9YYF5|A0A0J9YYF5_HUMAN,tr|A0A6Q8PG46|A0A6Q8PG46_HUMAN,tr|I3L464|I3L464_HUMAN" 10 1017.4727 1.96 26279 8859 2 1017.472896 509.7436 Nuclear distribution protein nudE homolog 1 OS=Homo sapiens OX=9606 GN=NDE1 PE=1 SV=3 4.25 2098.7 - 881580 - - - 0.1897 - 1.41 0.194 - 153.6 1 1 0 0.0002 8 0 0 0 8.36E+07 4.27E+07 - - - 1.5101 0.9993 221125_WJC_METTL3_EV_vs_WT_F03.08864.08864.2 0.0625 16-Oct K.SLDQDPVVR[166.11].A "sp|Q92598|HS105_HUMAN,tr|Q5TBM3|Q5TBM3_HUMAN,tr|A0A0A0MSM0|A0A0A0MSM0_HUMAN" 3 1037.5381 0.22 26282 8864 2 1037.538062 519.7763 Heat shock protein 105 kDa OS=Homo sapiens OX=9606 GN=HSPH1 PE=1 SV=1 4.21 2099.3 - 1.20E+07 - - - -0.0308 - 1.923 0.236 - 322.4 1 2 0 0 9 0 0 0 1.41E+08 6.45E+08 - - - 2.6758 0.9879 221125_WJC_METTL3_EV_vs_WT_F03.08866.08866.2 0.854 12-Jul K.SEISELR.R "sp|Q04695|K1C17_HUMAN,sp|P02533|K1C14_HUMAN,tr|F5GWP8|F5GWP8_HUMAN" 3 832.429 161.74 26284 8866 2 832.429034 417.2218 "Keratin, type I cytoskeletal 17 OS=Homo sapiens OX=9606 GN=KRT17 PE=1 SV=2" 4.53 2099.4 - 3.24E+06 - - - -0.0156 - 1.575 0.001 - 229.5 1 2 0 0 7 0 0 0 5.49E+09 3.40E+07 - - - 0.4877 0.9405 221125_WJC_METTL3_EV_vs_WT_F03.08869.08869.2 4.09 16-Jun R.LIPDGC[160.03]GVK[136.11].Y "sp|P27635|RL10_HUMAN,sp|Q96L21|RL10L_HUMAN,tr|F8W7C6|F8W7C6_HUMAN,tr|X1WI28|X1WI28_HUMAN" 4 965.5096 0.93 26286 8869 2 965.508196 483.7621 60S ribosomal protein L10 OS=Homo sapiens OX=9606 GN=RPL10 PE=1 SV=4 5.83 2099.7 - 667047 - - - -1.4055 - 1.155 0.06 - 81.3 3 2 0 -0.0014 9 0 0 0 4.84E+08 5.21E+08 - - - -0.3125 0.9994 221125_WJC_METTL3_EV_vs_WT_F03.08873.08873.2 0.0806 14-Jul K.SYAEELAK.H "sp|Q53GQ0|DHB12_HUMAN,tr|A0A1B0GV93|A0A1B0GV93_HUMAN,tr|A0A1B0GVY6|A0A1B0GVY6_HUMAN" 3 909.4444 0.9 26288 8873 2 909.443366 455.7295 Very-long-chain 3-oxoacyl-CoA reductase OS=Homo sapiens OX=9606 GN=HSD17B12 PE=1 SV=2 4.53 2100.2 - 2.85E+06 - - - -1.0963 - 1.318 0.439 - 139 1 2 0 -0.001 8 0 0 0 6.60E+07 7.33E+07 - - - 3.1159 0.9919 221125_WJC_METTL3_EV_vs_WT_F03.08881.08881.2 0.428 12-Jun K.EMLSVEK[136.11].A "sp|Q14683|SMC1A_HUMAN,tr|G8JLG1|G8JLG1_HUMAN" 2 842.4299 0.16 26294 8881 2 842.43067 422.2222 Structural maintenance of chromosomes protein 1A OS=Homo sapiens OX=9606 GN=SMC1A PE=1 SV=2 4.53 2100.9 - 1.67E+06 - - - 0.9081 - 1.27 0.153 - 119.6 1 2 0 0.0008 7 0 0 0 1.28E+07 8.04E+07 - - - 0.9282 0.9921 221125_WJC_METTL3_EV_vs_WT_F03.08886.08886.2 0.995 16-Aug K.SLDQDPVVR.A "sp|Q92598|HS105_HUMAN,tr|Q5TBM3|Q5TBM3_HUMAN,tr|A0A0A0MSM0|A0A0A0MSM0_HUMAN" 3 1027.5298 0.15 26298 8886 2 1027.529213 514.7722 Heat shock protein 105 kDa OS=Homo sapiens OX=9606 GN=HSPH1 PE=1 SV=1 4.21 2101.5 - 2.82E+06 - - - -0.5946 - 1.259 0.15 - 207.5 1 2 0 -0.0006 9 0 0 0 9.09E+07 6.22E+08 - - - 0.815 0.9997 221125_WJC_METTL3_EV_vs_WT_F03.08888.08888.2 0.0195 16-Jul R.VLLQEEGTR.K sp|P15924|DESP_HUMAN 1 1043.5611 15.16 26299 8888 2 1043.560654 522.7878 Desmoplakin OS=Homo sapiens OX=9606 GN=DSP PE=1 SV=3 4.53 2101.7 - 6.71E+06 - - - -0.4504 - 1.695 0.422 - 200.5 1 2 0 -0.0005 9 0 0 0 7.54E+08 4.97E+07 - - - 3.6844 0.9626 221125_WJC_METTL3_EV_vs_WT_F03.08889.08889.2 0.00918 16-Jul L.LVSNLNPER[166.11].V "sp|P26599|PTBP1_HUMAN,tr|A0A0U1RRM4|A0A0U1RRM4_HUMAN,tr|A6NLN1|A6NLN1_HUMAN,tr|A0A7I2V621|A0A7I2V621_HUMAN,tr|K7EK45|K7EK45_HUMAN" 5 1050.5697 0.61 26300 8889 2 1050.569644 526.2921 Polypyrimidine tract-binding protein 1 OS=Homo sapiens OX=9606 GN=PTBP1 PE=1 SV=1 6 2101.8 - 906154 - - - -0.08 - 1.437 0.362 - 152.2 1 1 0 -0.0001 9 0 0 0 6.72E+07 1.10E+08 - - - 2.7636 0.9916 221125_WJC_METTL3_EV_vs_WT_F03.08895.08895.2 0.27 12-Jul R.EQEIALR[166.11].R "sp|Q6Y7W6|GGYF2_HUMAN,sp|Q9NU22|MDN1_HUMAN,tr|A0A7I2V3H7|A0A7I2V3H7_HUMAN,tr|Q5T795|Q5T795_HUMAN,tr|I1E4Y6|I1E4Y6_HUMAN,tr|A0A7I2V516|A0A7I2V516_HUMAN,tr|A0A7I2V3H0|A0A7I2V3H0_HUMAN,tr|A0A7I2V361|A0A7I2V361_HUMAN,tr|E7ESB6|E7ESB6_HUMAN" 9 867.469 0.71 26304 8895 2 867.469361 434.7418 GRB10-interacting GYF protein 2 OS=Homo sapiens OX=9606 GN=GIGYF2 PE=1 SV=1 4.53 2102.4 - 1.59E+06 - - - 0.4726 - 1.45 0.078 - 349.6 1 2 0 0.0004 7 0 0 0 2.98E+08 4.18E+08 - - - 0.7943 0.9986 221125_WJC_METTL3_EV_vs_WT_F03.08898.08898.2 0.0363 14-Jun R.AQYDELAR.K "sp|P05783|K1C18_HUMAN,tr|F8VZY9|F8VZY9_HUMAN" 2 964.4614 2.08 26306 8898 2 964.460834 483.238 "Keratin, type I cytoskeletal 18 OS=Homo sapiens OX=9606 GN=KRT18 PE=1 SV=2" 4.37 2102.7 - 1.26E+06 - - - -0.5972 - 1.431 0.268 - 177.1 1 2 0 -0.0006 8 0 0 0 2.49E+08 1.20E+08 - - - 2.1011 0.9951 221125_WJC_METTL3_EV_vs_WT_F03.08899.08899.2 0.0671 14-Jul R.AQYDELAR[166.11].K "sp|P05783|K1C18_HUMAN,tr|F8VZY9|F8VZY9_HUMAN" 2 974.4697 2.08 26307 8899 2 974.471104 488.2421 "Keratin, type I cytoskeletal 18 OS=Homo sapiens OX=9606 GN=KRT18 PE=1 SV=2" 4.37 2102.8 - 727406 - - - 1.4613 - 1.407 0.193 - 247.3 1 2 0 0.0014 8 0 0 0 2.49E+08 1.20E+08 - - - 1.4959 0.9999 221125_WJC_METTL3_EV_vs_WT_F03.08902.08902.2 0.00314 14-Sep R.VAMIDETR[166.11].N "sp|Q16891|MIC60_HUMAN,tr|B9A067|B9A067_HUMAN,tr|A0A087WYS0|A0A087WYS0_HUMAN,tr|C9J406|C9J406_HUMAN,tr|H7C463|H7C463_HUMAN" 5 943.4672 1.41 26308 8902 2 943.466971 472.7409 MICOS complex subunit MIC60 OS=Homo sapiens OX=9606 GN=IMMT PE=1 SV=1 4.37 2103.2 - 2.80E+06 - - - -0.2819 - 2.095 0.453 - 280.4 1 2 0 -0.0003 8 0 0 0 1.57E+08 1.11E+08 - - - 4.6172 0.9987 221125_WJC_METTL3_EV_vs_WT_F03.08903.08903.2 0.0216 14-Aug R.DVAALASR.L "sp|Q6QNY0|BL1S3_HUMAN,tr|K7EN58|K7EN58_HUMAN" 2 801.4345 1.07 26309 8903 2 801.434441 401.7245 Biogenesis of lysosome-related organelles complex 1 subunit 3 OS=Homo sapiens OX=9606 GN=BLOC1S3 PE=1 SV=1 5.84 2103.2 - 2.52E+06 - - - -0.0324 - 1.461 0.261 - 260.9 1 2 0 0 8 0 0 0 1.21E+08 1.13E+08 - - - 2.1121 0.993 221125_WJC_METTL3_EV_vs_WT_F03.08905.08905.2 0.0973 14-Jun R.DVAALASR[166.11].L "sp|Q6QNY0|BL1S3_HUMAN,tr|K7EN58|K7EN58_HUMAN" 2 811.4427 1.14 26311 8905 2 811.440398 406.7286 Biogenesis of lysosome-related organelles complex 1 subunit 3 OS=Homo sapiens OX=9606 GN=BLOC1S3 PE=1 SV=1 5.84 2103.3 - 2.65E+06 - - - -2.8825 - 1.531 0.234 - 128.9 2 2 0 -0.0023 8 0 0 0 1.21E+08 1.06E+08 - - - 1.9187 0.9997 221125_WJC_METTL3_EV_vs_WT_F03.08906.08906.2 7.63E-06 20-Oct R.VLSQQAASVVK[136.11].Q "sp|P30566|PUR8_HUMAN,tr|A0A096LNY5|A0A096LNY5_HUMAN,tr|A0A1B0GTJ7|A0A1B0GTJ7_HUMAN,tr|A0A1B0GWJ0|A0A1B0GWJ0_HUMAN,tr|A0A0A6YY92|A0A0A6YY92_HUMAN,tr|A0A7P0T8E4|A0A7P0T8E4_HUMAN,tr|A0A7P0T9A7|A0A7P0T9A7_HUMAN,tr|A0A096LNY6|A0A096LNY6_HUMAN,tr|A0A7P0Z472|A0A7P0Z472_HUMAN" 9 1136.6645 0.67 26312 8906 2 1136.666244 569.3395 Adenylosuccinate lyase OS=Homo sapiens OX=9606 GN=ADSL PE=1 SV=2 8.72 2103.4 - 434536 - - - 1.5581 - 1.99 0.496 - 286.7 1 2 0 0.0018 11 0 0 0 3.73E+07 5.55E+07 - - - 4.5655 0.9909 221125_WJC_METTL3_EV_vs_WT_F03.08908.08908.2 0.345 12-Jul R.SAFLSQR[166.11].Y "sp|P35658|NU214_HUMAN,tr|A0A0A0MSW3|A0A0A0MSW3_HUMAN,tr|A0A494C1F2|A0A494C1F2_HUMAN" 3 817.4322 2.1 26313 8908 2 817.433111 409.7234 Nuclear pore complex protein Nup214 OS=Homo sapiens OX=9606 GN=NUP214 PE=1 SV=2 9.47 2103.6 - 1.38E+06 - - - 1.1487 - 1.502 0.081 - 233.6 1 2 0 0.0009 7 0 0 0 3.56E+08 1.70E+08 - - - 0.9279 0.7704 221125_WJC_METTL3_EV_vs_WT_F03.08911.08911.2 0.149 12-Aug L.STLVLNR.L "sp|P10809|CH60_HUMAN,tr|A0A7I2V2X6|A0A7I2V2X6_HUMAN,tr|A0A7I2YQK6|A0A7I2YQK6_HUMAN,tr|A0A7I2V599|A0A7I2V599_HUMAN,tr|A0A7I2V5M1|A0A7I2V5M1_HUMAN,tr|A0A7I2V5K3|A0A7I2V5K3_HUMAN" 6 801.4709 1.14 26315 8911 2 801.470191 401.7427 "60 kDa heat shock protein, mitochondrial OS=Homo sapiens OX=9606 GN=HSPD1 PE=1 SV=2" 9.47 2103.9 - 3.38E+06 - - - -0.8247 - 1.327 0.17 - 319.9 1 1 0 -0.0007 7 0 0 0 3.10E+08 2.72E+08 - - - 1.1929 0.999 221125_WJC_METTL3_EV_vs_WT_F03.08912.08912.2 0.0148 16-Aug K.IQTLTSSVR[166.11].E "sp|P16435|NCPR_HUMAN,tr|E7EWU0|E7EWU0_HUMAN,tr|H0Y4R2|H0Y4R2_HUMAN" 3 1013.5745 1.21 26316 8912 2 1013.575015 507.7945 NADPH--cytochrome P450 reductase OS=Homo sapiens OX=9606 GN=POR PE=1 SV=2 9.75 2104 - 2.56E+06 - - - 0.5288 - 1.919 0.204 - 183.6 1 2 0 0.0005 9 0 0 0 8.77E+07 7.26E+07 - - - 2.4333 0.9999 221125_WJC_METTL3_EV_vs_WT_F03.08914.08914.2 1.77E-06 20-Oct R.ATEATAMAMGR.G "sp|Q86YP4|P66A_HUMAN,tr|V9GY85|V9GY85_HUMAN,tr|V9GYX5|V9GYX5_HUMAN,tr|C9JJK9|C9JJK9_HUMAN,tr|H7C3H1|H7C3H1_HUMAN,tr|C9JVY3|C9JVY3_HUMAN,tr|C9JMI3|C9JMI3_HUMAN,tr|C9JGN4|C9JGN4_HUMAN" 8 1108.5005 1.45 26318 8914 2 1108.499486 555.2575 Transcriptional repressor p66-alpha OS=Homo sapiens OX=9606 GN=GATAD2A PE=1 SV=1 6.05 2104.1 - 1.46E+06 - - - -0.9274 - 2.344 0.564 - 419 1 2 0 -0.001 11 0 0 0 3.55E+07 2.44E+07 - - - 5.5109 0.9765 221125_WJC_METTL3_EV_vs_WT_F03.08915.08915.2 0.278 16-Jul R.ISC[160.03]FQSTVK[136.11].C "sp|Q9HAD4|WDR41_HUMAN,tr|D6RE66|D6RE66_HUMAN,tr|B4DK73|B4DK73_HUMAN,tr|D6RH33|D6RH33_HUMAN,tr|B4DHS8|B4DHS8_HUMAN,tr|D6R9E7|D6R9E7_HUMAN,tr|H0YAA3|H0YAA3_HUMAN,tr|D6RBY6|D6RBY6_HUMAN,tr|D6RB94|D6RB94_HUMAN" 9 1076.5416 0.2 26319 8915 2 1076.541591 539.2781 WD repeat-containing protein 41 OS=Homo sapiens OX=9606 GN=WDR41 PE=1 SV=3 8.22 2104.3 - 336362 - - - 0.0093 - 1.28 0.04 - 80.6 1 2 0 0 9 0 0 0 2.08E+06 1.05E+07 - - - 0.0506 0.9999 221125_WJC_METTL3_EV_vs_WT_F03.08919.08919.2 0.000483 13/20 R.ISSVLAGGSC[160.03]R.A "sp|P02533|K1C14_HUMAN,sp|P08779|K1C16_HUMAN,tr|K7ENV3|K7ENV3_HUMAN" 3 1105.555 17.52 26321 8919 2 1105.554321 553.7848 "Keratin, type I cytoskeletal 14 OS=Homo sapiens OX=9606 GN=KRT14 PE=1 SV=4" 8.25 2104.8 - 884473 - - - -0.6078 - 2.666 0.52 - 636.2 1 2 0 -0.0007 11 0 0 0 3.44E+07 1.96E+06 - - - 5.5342 0.9792 221125_WJC_METTL3_EV_vs_WT_F03.08920.08920.2 1.4 14-Jul K.ELALGQDR[166.11].L "sp|P30046|DOPD_HUMAN,sp|A6NHG4|DDTL_HUMAN,tr|J3KQ18|J3KQ18_HUMAN,tr|B5MC82|B5MC82_HUMAN" 4 910.4748 12.17 26322 8920 2 910.476596 456.2447 D-dopachrome decarboxylase OS=Homo sapiens OX=9606 GN=DDT PE=1 SV=3 4.37 2104.9 - 750243 - - - 2.011 - 1.359 0.098 - 166.4 1 2 0 0.0018 8 0 0 0 3.15E+08 2.59E+07 - - - 0.6894 0.9964 221125_WJC_METTL3_EV_vs_WT_F03.08921.08921.2 0.0103 16-Jul R.VLEEDESIR.T "sp|O43432|IF4G3_HUMAN,tr|A0A804HJV5|A0A804HJV5_HUMAN,tr|A0A0U1RQK7|A0A0U1RQK7_HUMAN,tr|A0A0A0MSA7|A0A0A0MSA7_HUMAN" 4 1088.535 0.76 26323 8921 2 1088.538321 545.2748 Eukaryotic translation initiation factor 4 gamma 3 OS=Homo sapiens OX=9606 GN=EIF4G3 PE=1 SV=2 4 2105 - 361294 - - - 3.0794 - 1.677 0.284 - 104.8 1 2 0 0.0034 9 0 0 0 1.13E+07 1.49E+07 - - - 2.6333 0.997 221125_WJC_METTL3_EV_vs_WT_F03.08924.08924.2 0.0253 14-Jul K.VC[160.03]NPIITK[136.11].L "sp|P11142|HSP7C_HUMAN,tr|E9PNE6|E9PNE6_HUMAN,tr|A8K7Q2|A8K7Q2_HUMAN,tr|E9PKE3|E9PKE3_HUMAN,tr|E9PS65|E9PS65_HUMAN" 5 951.5303 0.1 26324 8924 2 951.532952 476.7724 Heat shock cognate 71 kDa protein OS=Homo sapiens OX=9606 GN=HSPA8 PE=1 SV=1 8.19 2105.4 - 1.15E+06 - - - 2.7997 - 1.56 0.303 - 151.2 1 2 0 0.0027 8 0 0 0 1.97E+09 1.88E+10 - - - 2.6193 0.9995 221125_WJC_METTL3_EV_vs_WT_F03.08928.08928.2 0.000285 16-Sep R.VLEEDESIR[166.11].T "sp|O43432|IF4G3_HUMAN,tr|A0A804HJV5|A0A804HJV5_HUMAN,tr|A0A0U1RQK7|A0A0U1RQK7_HUMAN,tr|A0A0A0MSA7|A0A0A0MSA7_HUMAN" 4 1098.5432 0.76 26326 8928 2 1098.543242 550.2789 Eukaryotic translation initiation factor 4 gamma 3 OS=Homo sapiens OX=9606 GN=EIF4G3 PE=1 SV=2 4 2106 - 405690 - - - 0.0027 - 1.578 0.348 - 320.3 1 2 0 0 9 0 0 0 1.13E+07 1.49E+07 - - - 2.931 0.9968 221125_WJC_METTL3_EV_vs_WT_F03.08931.08931.2 0.705 18-Sep R.VAELNDVTAK[136.11].V "sp|Q8WVD5|RN141_HUMAN,tr|E9PQV2|E9PQV2_HUMAN,tr|E9PLX2|E9PLX2_HUMAN" 3 1066.575 1.7 26327 8931 2 1066.577687 534.2948 RING finger protein 141 OS=Homo sapiens OX=9606 GN=RNF141 PE=1 SV=1 4.37 2106.4 - 473798 - - - 2.5296 - 1.917 0.207 - 184.1 1 2 0 0.0027 10 0 0 0 1.82E+07 1.07E+07 - - - 2.3855 0.9998 221125_WJC_METTL3_EV_vs_WT_F03.08933.08933.2 0.000577 18-Nov K.LGSC[160.03]PEDQLR.C sp|Q8TCV5|WFDC5_HUMAN 1 1173.5448 999 26329 8933 2 1173.543508 587.7797 WAP four-disulfide core domain protein 5 OS=Homo sapiens OX=9606 GN=WFDC5 PE=1 SV=1 4.37 2106.6 - 282742 - - - -1.1197 - 2.106 0.498 - 230.3 1 2 0 -0.0013 10 0 0 0 1.61E+07 0.00E+00 - - - 4.7978 0.991 221125_WJC_METTL3_EV_vs_WT_F03.08937.08937.2 0.447 14-Jul K.QTLPVAPR.T "sp|Q6PJT7|ZC3HE_HUMAN,tr|G3V256|G3V256_HUMAN,tr|G3V5I6|G3V5I6_HUMAN,tr|H0YJA2|H0YJA2_HUMAN,tr|A0A087WTC9|A0A087WTC9_HUMAN" 5 880.5131 1.94 26331 8937 2 880.512315 441.2638 Zinc finger CCCH domain-containing protein 14 OS=Homo sapiens OX=9606 GN=ZC3H14 PE=1 SV=1 9.75 2107.1 - 2.57E+06 - - - -0.8359 - 1.433 0.087 - 224.2 1 2 0 -0.0007 8 0 0 0 1.36E+08 7.04E+07 - - - 0.7684 0.998 221125_WJC_METTL3_EV_vs_WT_F03.08942.08942.2 0.911 14-Jul R.LIDNISSR.E "sp|Q92552|RT27_HUMAN,tr|G5EA06|G5EA06_HUMAN,tr|D6RH20|D6RH20_HUMAN,tr|E5RJ73|E5RJ73_HUMAN,tr|D6RJC7|D6RJC7_HUMAN" 5 916.4978 0.92 26334 8942 2 916.497606 459.2562 "28S ribosomal protein S27, mitochondrial OS=Homo sapiens OX=9606 GN=MRPS27 PE=1 SV=3" 5.84 2107.6 - 2.32E+06 - - - -0.2062 - 1.406 0.235 - 134.8 1 2 0 -0.0002 8 0 0 0 3.67E+08 3.98E+08 - - - 1.8043 0.9972 221125_WJC_METTL3_EV_vs_WT_F03.08943.08943.2 0.948 14-Aug R.LIDNISSR[166.11].E "sp|Q92552|RT27_HUMAN,tr|G5EA06|G5EA06_HUMAN,tr|D6RH20|D6RH20_HUMAN,tr|E5RJ73|E5RJ73_HUMAN,tr|D6RJC7|D6RJC7_HUMAN" 5 926.5061 0.92 26335 8943 2 926.505727 464.2603 "28S ribosomal protein S27, mitochondrial OS=Homo sapiens OX=9606 GN=MRPS27 PE=1 SV=3" 5.84 2107.6 - 3.32E+06 - - - -0.3648 - 1.3 0.23 - 170.2 1 2 0 -0.0003 8 0 0 0 3.68E+08 4.00E+08 - - - 1.531 0.9779 221125_WJC_METTL3_EV_vs_WT_F03.08944.08944.2 0.514 12-Jul R.QVC[160.03]WGAR.D sp|Q5JTJ3|COA6_HUMAN 1 875.4072 1.42 26336 8944 2 875.406726 438.7109 Cytochrome c oxidase assembly factor 6 homolog OS=Homo sapiens OX=9606 GN=COA6 PE=1 SV=1 8.25 2107.7 - 816639 - - - -0.5483 - 1.112 0.1 - 176 1 2 0 -0.0005 7 0 0 0 4.91E+07 3.46E+07 - - - 0.1158 0.999 221125_WJC_METTL3_EV_vs_WT_F03.08954.08954.2 0.0208 16-Jul K.DVDGAYMTK.V sp|P04264|K2C1_HUMAN 1 998.4379 10.45 26341 8954 2 998.439078 500.2262 "Keratin, type II cytoskeletal 1 OS=Homo sapiens OX=9606 GN=KRT1 PE=1 SV=6" 4.21 2108.9 - 612698 - - - 1.1828 - 1.291 0.397 - 76.8 1 2 0 0.0012 9 0 0 0 2.57E+07 2.46E+06 - - - 2.7118 0.9991 221125_WJC_METTL3_EV_vs_WT_F03.08959.08959.2 5.22E-06 16-Sep K.DVDAAYMNK.V "sp|P48668|K2C6C_HUMAN,sp|P04259|K2C6B_HUMAN,sp|P13647|K2C5_HUMAN,sp|Q14CN4|K2C72_HUMAN,sp|O95678|K2C75_HUMAN,sp|P02538|K2C6A_HUMAN,tr|F8W0C6|F8W0C6_HUMAN,tr|H0YIN9|H0YIN9_HUMAN" 8 1025.4488 140.47 26343 8959 2 1025.450111 513.7317 "Keratin, type II cytoskeletal 6C OS=Homo sapiens OX=9606 GN=KRT6C PE=1 SV=3" 4.21 2109.5 - 2.26E+06 - - - 1.2824 - 1.653 0.327 - 193.9 1 2 0 0.0013 9 0 0 0 7.60E+09 5.41E+07 - - - 2.9098 0.9662 221125_WJC_METTL3_EV_vs_WT_F03.08960.08960.2 2.84 14-Jul R.QGGLGPIR[166.11].L "sp|Q13162|PRDX4_HUMAN,tr|A6NJJ0|A6NJJ0_HUMAN,tr|H7C3T4|H7C3T4_HUMAN" 3 806.4638 0.89 26344 8960 2 806.463793 404.2392 Peroxiredoxin-4 OS=Homo sapiens OX=9606 GN=PRDX4 PE=1 SV=1 9.75 2109.6 - 1.77E+06 - - - -0.0161 - 1.147 0.067 - 122.9 2 2 0 0 8 0 0 0 1.25E+08 1.41E+08 - - - -0.185 0.9048 221125_WJC_METTL3_EV_vs_WT_F03.08962.08962.2 7.42 12-Jun K.ASVDYIR.K "sp|O75030|MITF_HUMAN,sp|P19532|TFE3_HUMAN,sp|P19484|TFEB_HUMAN,tr|B0QYS7|B0QYS7_HUMAN,tr|B1AKB5|B1AKB5_HUMAN,tr|C9JBI8|C9JBI8_HUMAN,tr|B0QYS6|B0QYS6_HUMAN" 7 822.4236 0.01 26346 8962 2 822.423791 412.2191 Microphthalmia-associated transcription factor OS=Homo sapiens OX=9606 GN=MITF PE=1 SV=2 5.88 2109.9 - 468049 - - - 0.2711 - 1.072 0.004 - 119.9 2 2 0 0.0002 7 0 0 0 3.52E+07 5.04E+09 - - - -0.8437 0.9951 221125_WJC_METTL3_EV_vs_WT_F03.08963.08963.2 0.0137 20-Sep R.LEGAPATMTPK[136.11].L "sp|Q7L590|MCM10_HUMAN,tr|Q5T670|Q5T670_HUMAN" 2 1122.5834 5.57 26347 8963 2 1122.587076 562.299 Protein MCM10 homolog OS=Homo sapiens OX=9606 GN=MCM10 PE=1 SV=2 6 2110 - 195681 - - - 3.2336 - 1.548 0.304 - 178 1 2 0 0.0036 11 0 0 0 1.86E+07 3.35E+06 - - - 2.4673 0.9998 221125_WJC_METTL3_EV_vs_WT_F03.08965.08965.2 0.000689 16-Sep R.TLLEGEESR.M sp|P04264|K2C1_HUMAN 1 1032.5088 1801.51 26348 8965 2 1032.50907 517.2617 "Keratin, type II cytoskeletal 1 OS=Homo sapiens OX=9606 GN=KRT1 PE=1 SV=6" 4.25 2110.2 - 7.06E+06 - - - 0.3061 - 1.881 0.442 - 348.5 1 2 0 0.0003 9 0 0 0 6.11E+10 3.39E+07 - - - 4.1334 0.9955 221125_WJC_METTL3_EV_vs_WT_F03.08967.08967.2 0.0892 14-Sep R.LEYYENAR[166.11].K "sp|O14654|IRS4_HUMAN,tr|A0A804CF45|A0A804CF45_HUMAN" 2 1066.4959 0.51 26349 8967 2 1066.495101 534.2552 Insulin receptor substrate 4 OS=Homo sapiens OX=9606 GN=IRS4 PE=1 SV=1 4.53 2110.5 - 2.22E+06 - - - -0.7436 - 1.517 0.128 - 189.1 1 2 0 -0.0008 8 0 0 0 1.90E+08 3.69E+08 - - - 1.243 0.9059 221125_WJC_METTL3_EV_vs_WT_F03.08973.08973.2 3.96 14-Apr K.VC[160.03]NPIITK.L "sp|P11142|HSP7C_HUMAN,tr|E9PNE6|E9PNE6_HUMAN,tr|A8K7Q2|A8K7Q2_HUMAN,tr|E9PKE3|E9PKE3_HUMAN,tr|E9PS65|E9PS65_HUMAN" 5 943.5161 0.1 26352 8973 2 943.517314 472.7653 Heat shock cognate 71 kDa protein OS=Homo sapiens OX=9606 GN=HSPA8 PE=1 SV=1 8.19 2111.3 - 954860 - - - 1.2994 - 1.088 0.116 - 36.1 46 2 0 0.0012 8 0 0 0 1.96E+09 1.87E+10 - - - -0.591 0.9991 221125_WJC_METTL3_EV_vs_WT_F03.08980.08980.2 0.0216 12-Aug R.FC[160.03]ALEEK.C "sp|P52732|KIF11_HUMAN,tr|A0A7I2V3A9|A0A7I2V3A9_HUMAN" 2 895.411 4.51 26356 8980 2 895.410134 448.7128 Kinesin-like protein KIF11 OS=Homo sapiens OX=9606 GN=KIF11 PE=1 SV=2 4.53 2112 - 3.62E+07 - - - -0.9158 - 1.444 0.323 - 200.3 1 2 0 -0.0008 7 0 0 0 1.69E+09 3.75E+08 - - - 2.5906 0.9742 221125_WJC_METTL3_EV_vs_WT_F03.08981.08981.2 0.279 12-Jul R.EHLLLAR.Q sp|P49411|EFTU_HUMAN 1 850.5025 1.58 26357 8981 2 850.501182 426.2585 "Elongation factor Tu, mitochondrial OS=Homo sapiens OX=9606 GN=TUFM PE=1 SV=2" 6.85 2112 - 3.39E+06 - - - -1.5344 - 1.451 0.009 - 297.3 1 2 0 -0.0013 7 0 0 0 3.56E+08 2.26E+08 - - - 0.2866 0.9999 221125_WJC_METTL3_EV_vs_WT_F03.08982.08982.2 2.69E-05 18-Oct K.VVAEVYDQER.F "sp|Q9UHX1|PUF60_HUMAN,tr|A0A0J9YYL3|A0A0J9YYL3_HUMAN,tr|A0A0J9YXX5|A0A0J9YXX5_HUMAN,tr|A0A0J9YXJ8|A0A0J9YXJ8_HUMAN,tr|A0A0J9YVP6|A0A0J9YVP6_HUMAN" 5 1206.5881 1.22 26358 8982 2 1206.58828 604.3013 Poly(U)-binding-splicing factor PUF60 OS=Homo sapiens OX=9606 GN=PUF60 PE=1 SV=1 4.14 2112.2 - 973101 - - - 0.1765 - 2.071 0.529 - 357.5 1 2 0 0.0002 10 0 0 0 1.50E+08 1.23E+08 - - - 4.9803 0.9999 221125_WJC_METTL3_EV_vs_WT_F03.08989.08989.2 2.34E-07 18-Dec K.VVAEVYDQER[166.11].F "sp|Q9UHX1|PUF60_HUMAN,tr|A0A0J9YYL3|A0A0J9YYL3_HUMAN,tr|A0A0J9YXX5|A0A0J9YXX5_HUMAN,tr|A0A0J9YXJ8|A0A0J9YXJ8_HUMAN,tr|A0A0J9YVP6|A0A0J9YVP6_HUMAN" 5 1216.5963 1.22 26361 8989 2 1216.594947 609.3054 Poly(U)-binding-splicing factor PUF60 OS=Homo sapiens OX=9606 GN=PUF60 PE=1 SV=1 4.14 2113.1 - 1.70E+06 - - - -1.1425 - 2.3 0.529 - 340.8 1 2 0 -0.0014 10 0 0 0 1.50E+08 1.23E+08 - - - 5.2727 0.9955 221125_WJC_METTL3_EV_vs_WT_F03.08994.08994.2 0.0932 14-Aug R.QTATQLLK[136.11].L "sp|P62424|RL7A_HUMAN,tr|Q5T8U3|Q5T8U3_HUMAN" 2 909.5375 0.9 26364 8994 2 909.53999 455.776 60S ribosomal protein L7a OS=Homo sapiens OX=9606 GN=RPL7A PE=1 SV=2 8.75 2113.6 - 2.02E+06 - - - 2.7574 - 1.683 0.219 - 194.4 1 2 0 0.0025 8 0 0 0 2.01E+08 2.24E+08 - - - 2.2278 0.9291 221125_WJC_METTL3_EV_vs_WT_F03.09006.09006.2 1.73 14-Aug K.GALALEEK[136.11].R sp|P35579|MYH9_HUMAN 1 837.4687 0.97 26372 9006 2 837.466485 419.7416 Myosin-9 OS=Homo sapiens OX=9606 GN=MYH9 PE=1 SV=4 4.53 2114.8 - 6.49E+06 - - - -2.6843 - 1.498 0 - 186.4 2 2 0 -0.0022 8 0 0 0 2.42E+08 2.50E+08 - - - 0.1247 0.9952 221125_WJC_METTL3_EV_vs_WT_F03.09009.09009.2 0.0846 12-Aug R.EGYGGFR[166.11].G sp|Q9NR30|DDX21_HUMAN 1 794.3587 0.99 26373 9009 2 794.356301 398.1866 Nucleolar RNA helicase 2 OS=Homo sapiens OX=9606 GN=DDX21 PE=1 SV=5 6.1 2115.2 - 1.87E+06 - - - -2.9861 - 1.254 0.344 - 187.8 1 2 0 -0.0024 7 0 0 0 1.57E+08 1.58E+08 - - - 2.2982 0.9981 221125_WJC_METTL3_EV_vs_WT_F03.09011.09011.2 0.0321 14-Jul R.LEYYENAR.K "sp|O14654|IRS4_HUMAN,tr|A0A804CF45|A0A804CF45_HUMAN" 2 1056.4876 0.51 26374 9011 2 1056.487339 529.2511 Insulin receptor substrate 4 OS=Homo sapiens OX=9606 GN=IRS4 PE=1 SV=1 4.53 2115.4 - 5.28E+06 - - - -0.2698 - 1.478 0.217 - 198.6 1 2 0 -0.0003 8 0 0 0 1.89E+08 3.70E+08 - - - 1.822 0.9993 221125_WJC_METTL3_EV_vs_WT_F03.09017.09017.2 0.00128 18-Aug R.LITDNTVEER.L "sp|P28370|SMCA1_HUMAN,tr|A0A0A0MRP6|A0A0A0MRP6_HUMAN,tr|B7ZLQ5|B7ZLQ5_HUMAN" 3 1188.5986 1.19 26376 9017 2 1188.597798 595.3066 Probable global transcription activator SNF2L1 OS=Homo sapiens OX=9606 GN=SMARCA1 PE=1 SV=2 4.14 2116.1 - 1.84E+06 - - - -0.7017 - 1.548 0.346 - 182.5 1 2 0 -0.0008 10 0 0 0 2.44E+07 2.05E+07 - - - 2.816 0.9705 221125_WJC_METTL3_EV_vs_WT_F03.09021.09021.2 1.17 12-Jul R.EHLLLAR[166.11].Q sp|P49411|EFTU_HUMAN 1 860.5108 1.58 26378 9021 2 860.509526 431.2627 "Elongation factor Tu, mitochondrial OS=Homo sapiens OX=9606 GN=TUFM PE=1 SV=2" 6.85 2116.7 - 7.34E+06 - - - -1.4305 - 1.167 0.085 - 314.9 1 2 0 -0.0012 7 0 0 0 3.56E+08 2.26E+08 - - - 0.1578 0.9995 221125_WJC_METTL3_EV_vs_WT_F03.09026.09026.2 6.06E-08 13/18 R.MAGDPVANVR[166.11].F "sp|P30153|2AAA_HUMAN,tr|E9PH38|E9PH38_HUMAN,tr|B3KQV6|B3KQV6_HUMAN" 3 1038.5156 0.67 26381 9026 2 1038.512457 520.2651 Serine\threonine-protein phosphatase 2A 65 kDa regulatory subunit A alpha isoform OS=Homo sapiens OX=9606 GN=PPP2R1A PE=1 SV=4 5.59 2117.2 - 2.12E+06 - - - -3.011 - 2.169 0.523 - 643.8 1 2 0 -0.0031 10 0 0 0 1.15E+08 1.72E+08 - - - 5.0641 0.998 221125_WJC_METTL3_EV_vs_WT_F03.09029.09029.2 0.00212 14-Jun K.DDAITAYK[136.11].K "sp|Q9BY77|PDIP3_HUMAN,tr|F6VRR5|F6VRR5_HUMAN" 2 903.4429 0.36 26382 9029 2 903.439867 452.7287 Polymerase delta-interacting protein 3 OS=Homo sapiens OX=9606 GN=POLDIP3 PE=1 SV=2 4.21 2117.6 - 5.07E+06 - - - -3.3715 - 1.538 0.422 - 135.7 1 2 0 -0.003 8 0 0 0 3.35E+07 9.29E+07 - - - 3.4553 0.9984 221125_WJC_METTL3_EV_vs_WT_F03.09031.09031.2 0.233 14-Sep R.SSLVITTK[136.11].L "sp|Q13303|KCAB2_HUMAN,sp|Q14722|KCAB1_HUMAN,tr|C9JBV8|C9JBV8_HUMAN,tr|A0A087X1P8|A0A087X1P8_HUMAN,tr|A0A590UJJ4|A0A590UJJ4_HUMAN,tr|Q5TG78|Q5TG78_HUMAN,tr|A0A590UJY1|A0A590UJY1_HUMAN,tr|A0A590UJB8|A0A590UJB8_HUMAN,tr|C9JQ60|C9JQ60_HUMAN,tr|Q5TG84|Q5TG84_HUMAN,tr|F8W6W4|F8W6W4_HUMAN,tr|Q5TG81|Q5TG81_HUMAN,tr|A0A5F9UN28|A0A5F9UN28_HUMAN,tr|A0A590UJU1|A0A590UJU1_HUMAN,tr|A0A590UJB6|A0A590UJB6_HUMAN,tr|B7Z8E5|B7Z8E5_HUMAN" 16 855.5157 2.09 26384 9031 2 855.513663 428.7651 Voltage-gated potassium channel subunit beta-2 OS=Homo sapiens OX=9606 GN=KCNAB2 PE=1 SV=2 8.47 2117.8 - 1.88E+06 - - - -2.3623 - 1.856 0.271 - 252.9 1 2 0 -0.002 8 0 0 0 1.74E+08 8.36E+07 - - - 2.9071 0.7729 221125_WJC_METTL3_EV_vs_WT_F03.09034.09034.2 0.0183 16-Dec R.PSGLLAQER[166.11].K "sp|Q9Y2W1|TR150_HUMAN,tr|A0A3B3ITZ9|A0A3B3ITZ9_HUMAN" 2 979.5326 2.7 26385 9034 2 979.527501 490.7736 Thyroid hormone receptor-associated protein 3 OS=Homo sapiens OX=9606 GN=THRAP3 PE=1 SV=2 6.43 2118.2 - 3.42E+06 - - - -5.2198 - 2.545 0.302 - 453.2 1 1 0 -0.0051 9 0 0 0 1.10E+10 4.10E+09 - - - 3.9725 0.9945 221125_WJC_METTL3_EV_vs_WT_F03.09038.09038.2 0.0549 12-Aug R.SIC[160.03]MIQK.Y "sp|Q9BUK6|MSTO1_HUMAN,tr|A0A3B3IUD2|A0A3B3IUD2_HUMAN" 2 878.4354 0.17 26387 9038 2 878.434508 440.225 Protein misato homolog 1 OS=Homo sapiens OX=9606 GN=MSTO1 PE=1 SV=1 7.94 2118.7 - 825106 - - - -1.0097 - 1.295 0.176 - 192.4 1 2 0 -0.0009 7 0 0 0 5.43E+07 3.27E+08 - - - 1.1598 0.9933 221125_WJC_METTL3_EV_vs_WT_F03.09054.09054.2 0.00124 16-Sep R.FGQVYTEAK[136.11].R sp|P46977|STT3A_HUMAN 1 1049.5273 1.74 26394 9054 2 1049.522386 525.7709 Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit STT3A OS=Homo sapiens OX=9606 GN=STT3A PE=1 SV=2 6 2120.7 - 2.04E+06 - - - -4.6926 - 1.665 0.359 - 296.4 1 2 0 -0.0049 9 0 0 0 1.21E+08 6.97E+07 - - - 3.166 0.9997 221125_WJC_METTL3_EV_vs_WT_F03.09055.09055.2 0.00269 18-Oct K.TALIHDGLAR[166.11].G sp|P25398|RS12_HUMAN 1 1075.6014 1.77 26395 9055 2 1075.600051 538.808 40S ribosomal protein S12 OS=Homo sapiens OX=9606 GN=RPS12 PE=1 SV=3 6.41 2120.8 - 2.11E+06 - - - -1.2198 - 2.088 0.362 - 460.5 1 2 0 -0.0013 10 0 0 0 4.37E+08 2.47E+08 - - - 3.7693 0.9979 221125_WJC_METTL3_EV_vs_WT_F03.09058.09058.2 0.00739 14-Aug K.YENEVALR.Q "sp|P13645|K1C10_HUMAN,tr|A0A1B0GVI3|A0A1B0GVI3_HUMAN" 2 992.4927 221.78 26396 9058 2 992.491109 497.2536 "Keratin, type I cytoskeletal 10 OS=Homo sapiens OX=9606 GN=KRT10 PE=1 SV=6" 4.53 2121.2 - 3.29E+06 - - - -1.6131 - 1.378 0.292 - 181.8 1 2 0 -0.0016 8 0 0 0 9.61E+09 4.33E+07 - - - 2.1642 0.9996 221125_WJC_METTL3_EV_vs_WT_F03.09060.09060.2 0.00648 18-Sep K.TALIHDGLAR.G sp|P25398|RS12_HUMAN 1 1065.5931 1.77 26397 9060 2 1065.591775 533.8038 40S ribosomal protein S12 OS=Homo sapiens OX=9606 GN=RPS12 PE=1 SV=3 6.41 2121.4 - 4.80E+06 - - - -1.2369 - 2.058 0.355 - 321.6 1 2 0 -0.0013 10 0 0 0 4.37E+08 2.47E+08 - - - 3.6772 0.9852 221125_WJC_METTL3_EV_vs_WT_F03.09062.09062.2 0.00298 14-Aug K.C[160.03]GEALGLK.Q "sp|P78347|GTF2I_HUMAN,tr|A0A494C1K3|A0A494C1K3_HUMAN" 2 846.4269 1.28 26398 9062 2 846.423844 424.2207 General transcription factor II-I OS=Homo sapiens OX=9606 GN=GTF2I PE=1 SV=2 5.99 2121.6 - 6.47E+06 - - - -3.6565 - 1.639 0.167 - 241.8 1 2 0 -0.0031 8 0 0 0 1.17E+09 9.12E+08 - - - 1.7636 0.9997 221125_WJC_METTL3_EV_vs_WT_F03.09063.09063.2 0.00107 16-Nov K.AAILETAPK.E "sp|Q9P2E9|RRBP1_HUMAN,tr|A2A2S5|A2A2S5_HUMAN" 2 912.528 0.94 26399 9063 2 912.527584 457.2713 Ribosome-binding protein 1 OS=Homo sapiens OX=9606 GN=RRBP1 PE=1 SV=5 6.05 2121.7 - 4.23E+06 - - - -0.492 - 1.88 0.359 - 365.5 1 2 0 -0.0004 9 0 0 0 1.66E+08 1.76E+08 - - - 3.5187 0.9965 221125_WJC_METTL3_EV_vs_WT_F03.09067.09067.2 4.34 16-Aug R.FYESGSSLR.A sp|Q7Z353|HDX_HUMAN 1 1044.4876 5.52 26400 9067 2 1044.486987 523.2511 Highly divergent homeobox OS=Homo sapiens OX=9606 GN=HDX PE=1 SV=1 6 2122.3 - 1.65E+06 - - - -0.6099 - 1.329 0.208 - 156.8 1 2 0 -0.0006 9 0 0 0 6.50E+07 1.18E+07 - - - 1.3999 0.999 221125_WJC_METTL3_EV_vs_WT_F03.09070.09070.2 0.0724 16-Sep K.AAILETAPK[136.11].E "sp|Q9P2E9|RRBP1_HUMAN,tr|A2A2S5|A2A2S5_HUMAN" 2 920.5422 0.94 26403 9070 2 920.543614 461.2784 Ribosome-binding protein 1 OS=Homo sapiens OX=9606 GN=RRBP1 PE=1 SV=5 6.05 2122.5 - 4.19E+06 - - - 1.5002 - 1.645 0.325 - 272.1 1 2 0 0.0014 9 0 0 0 1.67E+08 1.77E+08 - - - 2.881 0.7807 221125_WJC_METTL3_EV_vs_WT_F03.09074.09074.2 0.102 16-Jul T.ALIHDGLAR.G sp|P25398|RS12_HUMAN 1 964.5454 1.02 26405 9074 2 964.543165 483.28 40S ribosomal protein S12 OS=Homo sapiens OX=9606 GN=RPS12 PE=1 SV=3 6.79 2123 - 2.79E+06 - - - -2.3317 - 1.613 0.221 - 186.2 2 1 0 -0.0022 9 0 0 0 1.21E+08 1.18E+08 - - - 1.9213 0.9864 221125_WJC_METTL3_EV_vs_WT_F03.09075.09075.2 0.316 14-Jun R.ELNITAAK.E "sp|P62081|RS7_HUMAN,tr|B5MCP9|B5MCP9_HUMAN,tr|A0A2R8Y623|A0A2R8Y623_HUMAN" 3 858.4811 0.84 26406 9075 2 858.480561 430.2478 40S ribosomal protein S7 OS=Homo sapiens OX=9606 GN=RPS7 PE=1 SV=1 6.1 2123 - 6.77E+06 - - - -0.6069 - 1.399 0.053 - 165.9 1 2 0 -0.0005 8 0 0 0 1.69E+09 2.02E+09 - - - 0.4449 0.9999 221125_WJC_METTL3_EV_vs_WT_F03.09085.09085.2 0.000205 20-Nov K.VGVASSEELAR.Q sp|O95721|SNP29_HUMAN 1 1116.5775 3.26 26410 9085 2 1116.577849 559.296 Synaptosomal-associated protein 29 OS=Homo sapiens OX=9606 GN=SNAP29 PE=1 SV=1 4.53 2124.3 - 8.83E+06 - - - 0.3108 - 2.464 0.543 - 548.8 1 2 0 0.0003 11 0 0 0 3.93E+08 1.21E+08 - - - 5.491 0.994 221125_WJC_METTL3_EV_vs_WT_F03.09088.09088.2 0.175 18-Oct K.ILGPQGNTIK[136.11].R sp|Q07666|KHDR1_HUMAN 1 1047.6168 0.93 26411 9088 2 1047.614219 524.8157 "KH domain-containing, RNA-binding, signal transduction-associated protein 1 OS=Homo sapiens OX=9606 GN=KHDRBS1 PE=1 SV=1" 8.75 2124.7 - 2.53E+06 - - - -2.4589 - 1.591 0.196 - 197.3 1 2 0 -0.0026 10 0 0 0 5.12E+08 5.53E+08 - - - 1.784 0.9996 221125_WJC_METTL3_EV_vs_WT_F03.09090.09090.2 0.00108 16-Nov R.AEDAVEAIR[166.11].G "sp|Q9BWF3|RBM4_HUMAN,sp|Q9BQ04|RBM4B_HUMAN,tr|E9PM61|E9PM61_HUMAN,tr|D6R9K7|D6R9K7_HUMAN,tr|J3QRR5|J3QRR5_HUMAN,tr|E9PB51|E9PB51_HUMAN,tr|U3KQD5|U3KQD5_HUMAN,tr|E9PLB0|E9PLB0_HUMAN" 8 982.4959 1.43 26413 9090 2 982.493806 492.2552 RNA-binding protein 4 OS=Homo sapiens OX=9606 GN=RBM4 PE=1 SV=1 4.14 2124.8 - 1.10E+08 - - - -2.1252 - 2.209 0.42 - 659.2 1 2 0 -0.0021 9 0 0 0 5.44E+09 3.79E+09 - - - 4.4353 0.9907 221125_WJC_METTL3_EV_vs_WT_F03.09094.09094.2 0.0365 14-Jul R.ELNITAAK[136.11].E "sp|P62081|RS7_HUMAN,tr|B5MCP9|B5MCP9_HUMAN,tr|A0A2R8Y623|A0A2R8Y623_HUMAN" 3 866.4953 0.84 26416 9094 2 866.493529 434.2549 40S ribosomal protein S7 OS=Homo sapiens OX=9606 GN=RPS7 PE=1 SV=1 6.1 2125.3 - 4.08E+07 - - - -2.0242 - 1.476 0.136 - 296.2 1 2 0 -0.0018 8 0 0 0 1.69E+09 2.02E+09 - - - 1.2192 0.9325 221125_WJC_METTL3_EV_vs_WT_F03.09096.09096.2 0.602 12-Aug R.SQILSVK.S sp|Q6KB66|K2C80_HUMAN 1 773.4647 2.61 26417 9096 2 773.462359 387.7396 "Keratin, type II cytoskeletal 80 OS=Homo sapiens OX=9606 GN=KRT80 PE=1 SV=2" 8.47 2125.5 - 4.09E+06 - - - -3.0318 - 1.372 0.038 - 298 1 2 0 -0.0023 7 0 0 0 1.22E+08 4.69E+07 - - - 0.323 0.9939 221125_WJC_METTL3_EV_vs_WT_F03.09098.09098.2 0.178 14-Jul R.FSGGFGAR.D "sp|O00571|DDX3X_HUMAN,sp|O15523|DDX3Y_HUMAN,tr|A0A2R8YFR4|A0A2R8YFR4_HUMAN,tr|A0A2R8YCW1|A0A2R8YCW1_HUMAN,tr|A0A2R8YDT5|A0A2R8YDT5_HUMAN,tr|A0A2R8Y645|A0A2R8Y645_HUMAN,tr|A0A2R8YF78|A0A2R8YF78_HUMAN,tr|A0A0D9SFB3|A0A0D9SFB3_HUMAN,tr|A0A2R8YFS5|A0A2R8YFS5_HUMAN,tr|A0A0D9SF53|A0A0D9SF53_HUMAN,tr|A0A087WVZ1|A0A087WVZ1_HUMAN,tr|A0A0J9YVQ7|A0A0J9YVQ7_HUMAN,tr|A0A2R8Y5G6|A0A2R8Y5G6_HUMAN,tr|A0A2R8Y7T2|A0A2R8Y7T2_HUMAN,tr|A0A0D9SG12|A0A0D9SG12_HUMAN,tr|F6S8Q4|F6S8Q4_HUMAN,tr|A0A2U3TZJ9|A0A2U3TZJ9_HUMAN,tr|A0A2R8Y4A4|A0A2R8Y4A4_HUMAN" 18 797.382 1.14 26418 9098 2 797.381331 399.6983 ATP-dependent RNA helicase DDX3X OS=Homo sapiens OX=9606 GN=DDX3X PE=1 SV=3 9.75 2125.7 - 3.13E+06 - - - -0.8854 - 1.32 0.159 - 85.4 1 2 0 -0.0007 8 0 0 0 7.19E+08 6.30E+08 - - - 1.0525 0.9762 221125_WJC_METTL3_EV_vs_WT_F03.09099.09099.2 0.0006 22-Nov R.MFGGPGTASRPS.S "sp|P08670|VIME_HUMAN,tr|B0YJC4|B0YJC4_HUMAN,tr|A0A1B0GVG8|A0A1B0GVG8_HUMAN,tr|A0A1B0GTT5|A0A1B0GTT5_HUMAN" 4 1163.5393 1.75 26419 9099 2 1163.537755 582.7769 Vimentin OS=Homo sapiens OX=9606 GN=VIM PE=1 SV=4 9.5 2125.9 - 924492 - - - -1.3639 - 1.687 0.437 - 193 1 1 0 -0.0016 12 0 0 0 4.09E+07 2.34E+07 - - - 3.6442 0.9985 221125_WJC_METTL3_EV_vs_WT_F03.09100.09100.2 0.0426 18-Dec K.ILGPQGNTIK.R sp|Q07666|KHDR1_HUMAN 1 1039.6026 0.93 26420 9100 2 1039.601915 520.8086 "KH domain-containing, RNA-binding, signal transduction-associated protein 1 OS=Homo sapiens OX=9606 GN=KHDRBS1 PE=1 SV=1" 8.75 2126 - 3.27E+06 - - - -0.6541 - 1.456 0.27 - 330.9 1 2 0 -0.0007 10 0 0 0 5.12E+08 5.53E+08 - - - 2.0837 0.9672 221125_WJC_METTL3_EV_vs_WT_F03.09101.09101.2 0.692 12-Jul K.QFAQALR.K sp|O60825|F262_HUMAN 1 832.4555 2.35 26421 9101 2 832.453415 417.235 "6-phosphofructo-2-kinase\fructose-2,6-bisphosphatase 2 OS=Homo sapiens OX=9606 GN=PFKFB2 PE=1 SV=2" 9.75 2126.1 - 2.51E+06 - - - -2.5479 - 1.395 0.067 - 269.1 1 2 0 -0.0021 7 0 0 0 1.07E+08 4.54E+07 - - - 0.59 0.9991 221125_WJC_METTL3_EV_vs_WT_F03.09104.09104.2 0.000264 20-Nov R.VIGEDGQSVYK.L "sp|Q9UHD2|TBK1_HUMAN,tr|A0A7I2V646|A0A7I2V646_HUMAN,tr|A0A7I2V4Z2|A0A7I2V4Z2_HUMAN,tr|A0A494C079|A0A494C079_HUMAN,tr|A0A494C045|A0A494C045_HUMAN,tr|A0A494C1M6|A0A494C1M6_HUMAN,tr|A0A494C0A8|A0A494C0A8_HUMAN,tr|A0A494C1I2|A0A494C1I2_HUMAN,tr|A0A7I2V4W4|A0A7I2V4W4_HUMAN,tr|A0A7I2V322|A0A7I2V322_HUMAN,tr|A0A7I2V3E0|A0A7I2V3E0_HUMAN,tr|A0A7I2V463|A0A7I2V463_HUMAN,tr|A0A494C148|A0A494C148_HUMAN,tr|A0A494C0X2|A0A494C0X2_HUMAN,tr|A0A7I2V615|A0A7I2V615_HUMAN,tr|A0A494C167|A0A494C167_HUMAN,tr|A0A7I2V2F4|A0A7I2V2F4_HUMAN,tr|A0A494C0R4|A0A494C0R4_HUMAN,tr|A0A7I2V643|A0A7I2V643_HUMAN,tr|A0A7I2V4Y1|A0A7I2V4Y1_HUMAN" 20 1193.5928 1.55 26424 9104 2 1193.589623 597.8037 Serine\threonine-protein kinase TBK1 OS=Homo sapiens OX=9606 GN=TBK1 PE=1 SV=1 4.37 2126.5 - 933937 - - - -2.6768 - 1.697 0.438 - 107.5 1 2 0 -0.0032 11 0 0 0 3.23E+07 2.09E+07 - - - 3.7058 0.9998 221125_WJC_METTL3_EV_vs_WT_F03.09108.09108.2 0.000256 16-Sep R.AEDAVEAIR.G "sp|Q9BWF3|RBM4_HUMAN,sp|Q9BQ04|RBM4B_HUMAN,tr|E9PM61|E9PM61_HUMAN,tr|D6R9K7|D6R9K7_HUMAN,tr|J3QRR5|J3QRR5_HUMAN,tr|E9PB51|E9PB51_HUMAN,tr|U3KQD5|U3KQD5_HUMAN,tr|E9PLB0|E9PLB0_HUMAN" 8 972.4876 1.44 26426 9108 2 972.487062 487.2511 RNA-binding protein 4 OS=Homo sapiens OX=9606 GN=RBM4 PE=1 SV=1 4.14 2126.9 - 1.94E+08 - - - -0.5779 - 2.107 0.44 - 385 1 2 0 -0.0006 9 0 0 0 5.43E+09 3.77E+09 - - - 4.4468 0.9998 221125_WJC_METTL3_EV_vs_WT_F03.09113.09113.2 0.0353 15/22 K.LGAAAADAVTGR[166.11].T "sp|Q9H4A3|WNK1_HUMAN,tr|F5GWT4|F5GWT4_HUMAN,tr|F6UYG0|F6UYG0_HUMAN" 3 1081.5755 1.63 26429 9113 2 1081.574825 541.795 Serine\threonine-protein kinase WNK1 OS=Homo sapiens OX=9606 GN=WNK1 PE=1 SV=2 5.84 2127.5 - 1.42E+06 - - - -0.6629 - 2.878 0.365 - 1106.3 1 2 0 -0.0007 12 0 0 0 2.08E+08 1.27E+08 - - - 4.5181 0.9965 221125_WJC_METTL3_EV_vs_WT_F03.09118.09118.2 0.234 14-Aug R.TITSTYYR[166.11].G sp|Q15286|RAB35_HUMAN 1 1013.5057 0.65 26432 9118 2 1013.505085 507.7601 Ras-related protein Rab-35 OS=Homo sapiens OX=9606 GN=RAB35 PE=1 SV=1 8.25 2128.2 - 946973 - - - -0.6374 - 1.329 0.203 - 196 1 2 0 -0.0006 8 0 0 0 2.75E+07 4.20E+07 - - - 1.398 0.9773 221125_WJC_METTL3_EV_vs_WT_F03.09121.09121.2 0.871 12-Jun R.LASYLDK.V "sp|Q04695|K1C17_HUMAN,sp|Q99456|K1C12_HUMAN,sp|P13645|K1C10_HUMAN,sp|P02533|K1C14_HUMAN,sp|P08727|K1C19_HUMAN,sp|P35527|K1C9_HUMAN,sp|P08779|K1C16_HUMAN,sp|P19012|K1C15_HUMAN,tr|K7EPJ9|K7EPJ9_HUMAN,tr|C9JM50|C9JM50_HUMAN,tr|A0A1B0GVI3|A0A1B0GVI3_HUMAN,tr|A0A3B3ITG2|A0A3B3ITG2_HUMAN" 12 808.4331 293.23 26433 9121 2 808.430558 405.2238 "Keratin, type I cytoskeletal 17 OS=Homo sapiens OX=9606 GN=KRT17 PE=1 SV=2" 5.83 2128.6 - 1.61E+07 - - - -3.1072 - 1.196 0.207 - 91.2 1 2 0 -0.0025 7 0 0 0 6.16E+09 2.10E+07 - - - 1.1362 0.9975 221125_WJC_METTL3_EV_vs_WT_F03.09122.09122.2 0.199 12-Jul R.LTDYISK.V sp|O75915|PRAF3_HUMAN 1 838.4436 0.94 26434 9122 2 838.442218 420.2291 PRA1 family protein 3 OS=Homo sapiens OX=9606 GN=ARL6IP5 PE=1 SV=1 5.83 2128.6 - 3.21E+06 - - - -1.6888 - 1.362 0.275 - 132.7 1 2 0 -0.0014 7 0 0 0 9.09E+07 9.71E+07 - - - 2.0506 0.9999 221125_WJC_METTL3_EV_vs_WT_F03.09125.09125.2 0.00559 13/22 K.LGAAAADAVTGR.T "sp|Q9H4A3|WNK1_HUMAN,tr|F5GWT4|F5GWT4_HUMAN,tr|F6UYG0|F6UYG0_HUMAN" 3 1071.5673 1.63 26435 9125 2 1071.566707 536.7909 Serine\threonine-protein kinase WNK1 OS=Homo sapiens OX=9606 GN=WNK1 PE=1 SV=2 5.84 2129 - 4.60E+06 - - - -0.5273 - 2.767 0.406 - 707.2 1 2 0 -0.0006 12 0 0 0 2.08E+08 1.27E+08 - - - 4.7174 0.9993 221125_WJC_METTL3_EV_vs_WT_F03.09126.09126.2 0.00823 18-Oct K.GTAVVNGEFK.D sp|P30048|PRDX3_HUMAN 1 1020.524 0.53 26436 9126 2 1020.525123 511.2693 "Thioredoxin-dependent peroxide reductase, mitochondrial OS=Homo sapiens OX=9606 GN=PRDX3 PE=1 SV=3" 6 2129.1 - 1.97E+06 - - - 1.0906 - 1.73 0.332 - 300.9 1 2 0 0.0011 10 0 0 0 5.01E+07 9.43E+07 - - - 3.0228 0.9348 221125_WJC_METTL3_EV_vs_WT_F03.09127.09127.2 1.11 14-Jun R.EC[160.03]TIEATA.- sp|P62633|CNBP_HUMAN 1 893.38 - 26437 9127 2 893.37961 447.6973 CCHC-type zinc finger nucleic acid binding protein OS=Homo sapiens OX=9606 GN=CNBP PE=1 SV=1 3.8 2129.2 - 3.02E+06 - - - -0.4903 - 0.744 0.17 - 96.1 1 2 0 -0.0004 8 0 0 0 - - - - - -0.5954 0.9997 221125_WJC_METTL3_EV_vs_WT_F03.09130.09130.2 5.50E-05 16-Oct K.FESPEVAER.A "sp|P52272|HNRPM_HUMAN,tr|A0A087X0X3|A0A087X0X3_HUMAN" 2 1062.4982 1.75 26438 9130 2 1062.496127 532.2564 Heterogeneous nuclear ribonucleoprotein M OS=Homo sapiens OX=9606 GN=HNRNPM PE=1 SV=3 4.25 2129.6 - 8.06E+06 - - - -1.9407 - 1.889 0.527 - 413.6 1 2 0 -0.0021 9 0 0 0 4.69E+09 2.68E+09 - - - 4.7729 0.9997 221125_WJC_METTL3_EV_vs_WT_F03.09131.09131.2 0.00015 16-Aug K.MSSPLADAK.R sp|P49790|NU153_HUMAN 1 918.4481 1.11 26439 9131 2 918.447227 460.2313 Nuclear pore complex protein Nup153 OS=Homo sapiens OX=9606 GN=NUP153 PE=1 SV=2 5.59 2129.6 - 1.56E+06 - - - -0.9157 - 1.672 0.447 - 193.9 1 2 0 -0.0008 9 0 0 0 1.47E+08 1.32E+08 - - - 3.8294 0.9954 221125_WJC_METTL3_EV_vs_WT_F03.09133.09133.2 3.06 16-Aug K.MSSPLADAK[136.11].R sp|P49790|NU153_HUMAN 1 926.4623 1.17 26441 9133 2 926.461001 464.2384 Nuclear pore complex protein Nup153 OS=Homo sapiens OX=9606 GN=NUP153 PE=1 SV=2 5.59 2129.8 - 1.52E+06 - - - -1.3676 - 1.563 0.148 - 157 1 2 0 -0.0013 9 0 0 0 1.46E+08 1.25E+08 - - - 1.4258 0.9998 221125_WJC_METTL3_EV_vs_WT_F03.09134.09134.2 0.0125 18-Dec R.QLESGGFEAR.L sp|Q8IYI6|EXOC8_HUMAN 1 1092.52 1.87 26442 9134 2 1092.519776 547.2673 Exocyst complex component 8 OS=Homo sapiens OX=9606 GN=EXOC8 PE=1 SV=2 4.53 2130 - 1.50E+06 - - - -0.1931 - 2.292 0.422 - 739.5 1 2 0 -0.0002 10 0 0 0 8.91E+07 4.76E+07 - - - 4.473 0.9998 221125_WJC_METTL3_EV_vs_WT_F03.09135.09135.2 1.07E-05 13/20 K.VVGDVAYDEAK.E "sp|P11586|C1TC_HUMAN,tr|F5H2F4|F5H2F4_HUMAN,tr|V9GZ78|V9GZ78_HUMAN,tr|V9GYY3|V9GYY3_HUMAN" 4 1164.5663 1.63 26443 9135 2 1164.568161 583.2904 "C-1-tetrahydrofolate synthase, cytoplasmic OS=Homo sapiens OX=9606 GN=MTHFD1 PE=1 SV=4" 4.03 2130.1 - 1.45E+06 - - - 1.6246 - 2.134 0.533 - 468.8 1 2 0 0.0019 11 0 0 0 1.91E+08 1.17E+08 - - - 5.0277 0.9542 221125_WJC_METTL3_EV_vs_WT_F03.09137.09137.2 0.437 16-Oct R.PSGLLAQER.K "sp|Q9Y2W1|TR150_HUMAN,tr|A0A3B3ITZ9|A0A3B3ITZ9_HUMAN" 2 969.5243 2.7 26444 9137 2 969.523281 485.7694 Thyroid hormone receptor-associated protein 3 OS=Homo sapiens OX=9606 GN=THRAP3 PE=1 SV=2 6.43 2130.3 - 1.88E+08 - - - -1.0964 - 2.204 0.197 - 319.3 1 1 0 -0.0011 9 0 0 0 1.10E+10 4.09E+09 - - - 2.782 0.9917 221125_WJC_METTL3_EV_vs_WT_F03.09138.09138.2 0.147 14-Jul K.VYVSDNIR.L sp|Q8TEM1|PO210_HUMAN 1 964.4978 55.81 26445 9138 2 964.49339 483.2562 Nuclear pore membrane glycoprotein 210 OS=Homo sapiens OX=9606 GN=NUP210 PE=1 SV=3 5.81 2130.4 - 4.44E+06 - - - -4.5671 - 1.49 0.353 - 202.4 1 2 0 -0.0044 8 0 0 0 1.27E+08 2.27E+06 - - - 2.8496 0.9995 221125_WJC_METTL3_EV_vs_WT_F03.09139.09139.2 0.000954 18-Oct K.LLNTVEETTK.D "sp|P52732|KIF11_HUMAN,tr|A0A7I2YQY4|A0A7I2YQY4_HUMAN,tr|A0A7I2V3A9|A0A7I2V3A9_HUMAN" 3 1146.6132 4.36 26446 9139 2 1146.615607 574.3139 Kinesin-like protein KIF11 OS=Homo sapiens OX=9606 GN=KIF11 PE=1 SV=2 4.53 2130.5 - 1.26E+06 - - - 2.0827 - 1.991 0.429 - 208 1 2 0 0.0024 10 0 0 0 4.33E+09 9.93E+08 - - - 4.131 0.9674 221125_WJC_METTL3_EV_vs_WT_F03.09140.09140.2 0.0786 16-Aug R.VVDTLYNGK.L "sp|Q07157|ZO1_HUMAN,tr|A0A087X0K9|A0A087X0K9_HUMAN,tr|G5E9E7|G5E9E7_HUMAN,tr|A0A0G2JNH2|A0A0G2JNH2_HUMAN,tr|G3V1L9|G3V1L9_HUMAN,tr|A0A7I2V5U5|A0A7I2V5U5_HUMAN" 6 1007.5288 0.86 26447 9140 2 1007.525073 504.7717 Tight junction protein ZO-1 OS=Homo sapiens OX=9606 GN=TJP1 PE=1 SV=3 5.81 2130.6 - 642496 - - - -3.6604 - 1.452 0.141 - 165 1 2 0 -0.0037 9 0 0 0 2.91E+07 3.38E+07 - - - 1.1602 0.9996 221125_WJC_METTL3_EV_vs_WT_F03.09143.09143.2 0.00448 20-Dec K.VVGDVAYDEAK[136.11].E "sp|P11586|C1TC_HUMAN,tr|F5H2F4|F5H2F4_HUMAN,tr|V9GZ78|V9GZ78_HUMAN,tr|V9GYY3|V9GYY3_HUMAN" 4 1172.5805 1.63 26448 9143 2 1172.579156 587.2975 "C-1-tetrahydrofolate synthase, cytoplasmic OS=Homo sapiens OX=9606 GN=MTHFD1 PE=1 SV=4" 4.03 2131 - 1.38E+06 - - - -1.1198 - 1.756 0.387 - 162.3 1 2 0 -0.0013 11 0 0 0 1.91E+08 1.17E+08 - - - 3.4221 0.9944 221125_WJC_METTL3_EV_vs_WT_F03.09144.09144.2 0.139 12-Aug R.LELC[160.03]DER.V sp|P07919|QCR6_HUMAN 1 933.4226 1.37 26449 9144 2 933.42038 467.7186 "Cytochrome b-c1 complex subunit 6, mitochondrial OS=Homo sapiens OX=9606 GN=UQCRH PE=1 SV=2" 4.14 2131.1 - 1.38E+06 - - - -2.3591 - 1.538 0.187 - 231.9 1 2 0 -0.0022 7 0 0 0 4.78E+07 3.50E+07 - - - 1.7855 0.9982 221125_WJC_METTL3_EV_vs_WT_F03.09146.09146.2 0.00313 18-Dec R.QLESGGFEAR[166.11].L sp|Q8IYI6|EXOC8_HUMAN 1 1102.5283 1.87 26451 9146 2 1102.52333 552.2714 Exocyst complex component 8 OS=Homo sapiens OX=9606 GN=EXOC8 PE=1 SV=2 4.53 2131.3 - 1.50E+06 - - - -4.4688 - 2.211 0.455 - 639.5 1 2 0 -0.0049 10 0 0 0 8.84E+07 4.71E+07 - - - 4.6148 0.9991 221125_WJC_METTL3_EV_vs_WT_F03.09147.09147.2 1.62E-05 20-Oct R.VIGEDGQSVYK[136.11].L "sp|Q9UHD2|TBK1_HUMAN,tr|A0A7I2V646|A0A7I2V646_HUMAN,tr|A0A7I2V4Z2|A0A7I2V4Z2_HUMAN,tr|A0A494C079|A0A494C079_HUMAN,tr|A0A494C045|A0A494C045_HUMAN,tr|A0A494C1M6|A0A494C1M6_HUMAN,tr|A0A494C0A8|A0A494C0A8_HUMAN,tr|A0A494C1I2|A0A494C1I2_HUMAN,tr|A0A7I2V4W4|A0A7I2V4W4_HUMAN,tr|A0A7I2V322|A0A7I2V322_HUMAN,tr|A0A7I2V3E0|A0A7I2V3E0_HUMAN,tr|A0A7I2V463|A0A7I2V463_HUMAN,tr|A0A494C148|A0A494C148_HUMAN,tr|A0A494C0X2|A0A494C0X2_HUMAN,tr|A0A7I2V615|A0A7I2V615_HUMAN,tr|A0A494C167|A0A494C167_HUMAN,tr|A0A7I2V2F4|A0A7I2V2F4_HUMAN,tr|A0A494C0R4|A0A494C0R4_HUMAN,tr|A0A7I2V643|A0A7I2V643_HUMAN,tr|A0A7I2V4Y1|A0A7I2V4Y1_HUMAN" 20 1201.607 1.55 26452 9147 2 1201.602717 601.8108 Serine\threonine-protein kinase TBK1 OS=Homo sapiens OX=9606 GN=TBK1 PE=1 SV=1 4.37 2131.4 - 745073 - - - -3.5794 - 2.058 0.515 - 209.1 1 2 0 -0.0043 11 0 0 0 3.23E+07 2.09E+07 - - - 4.7959 0.9997 221125_WJC_METTL3_EV_vs_WT_F03.09150.09150.2 0.00106 18-Oct K.LLNTVEETTK[136.11].D "sp|P52732|KIF11_HUMAN,tr|A0A7I2YQY4|A0A7I2YQY4_HUMAN,tr|A0A7I2V3A9|A0A7I2V3A9_HUMAN" 3 1154.6274 4.36 26453 9150 2 1154.628234 578.321 Kinesin-like protein KIF11 OS=Homo sapiens OX=9606 GN=KIF11 PE=1 SV=2 4.53 2131.8 - 1.44E+06 - - - 0.7059 - 1.923 0.412 - 288.1 1 2 0 0.0008 10 0 0 0 4.33E+09 9.93E+08 - - - 3.909 0.9992 221125_WJC_METTL3_EV_vs_WT_F03.09151.09151.2 0.000162 16-Oct R.QFVPGDEPR[166.11].E sp|P09543|CN37_HUMAN 1 1053.5119 0.17 26454 9151 2 1053.509202 527.7632 "2',3'-cyclic-nucleotide 3'-phosphodiesterase OS=Homo sapiens OX=9606 GN=CNP PE=1 SV=2" 4.37 2131.9 - 1.52E+06 - - - -2.541 - 1.911 0.396 - 445.9 1 2 0 -0.0027 9 0 0 0 1.35E+07 7.87E+07 - - - 3.8386 0.9948 221125_WJC_METTL3_EV_vs_WT_F03.09157.09157.2 1.19 14-Jul K.NLVDNVAK[136.11].D "sp|Q9BZE4|GTPB4_HUMAN,tr|Q5T3R7|Q5T3R7_HUMAN" 2 879.4905 0.8 26457 9157 2 879.489745 440.7525 GTP-binding protein 4 OS=Homo sapiens OX=9606 GN=GTPBP4 PE=1 SV=3 5.84 2132.6 - 1.88E+06 - - - -0.8937 - 1.433 0.142 - 127.2 1 2 0 -0.0008 8 0 0 0 5.63E+07 7.01E+07 - - - 1.1746 0.9998 221125_WJC_METTL3_EV_vs_WT_F03.09158.09158.2 0.000351 16-Sep K.FESPEVAER[166.11].A "sp|P52272|HNRPM_HUMAN,tr|A0A087X0X3|A0A087X0X3_HUMAN" 2 1072.5065 1.75 26458 9158 2 1072.506057 537.2605 Heterogeneous nuclear ribonucleoprotein M OS=Homo sapiens OX=9606 GN=HNRNPM PE=1 SV=3 4.25 2132.6 - 8.17E+06 - - - -0.3748 - 1.664 0.469 - 315.9 1 2 0 -0.0004 9 0 0 0 4.68E+09 2.68E+09 - - - 3.9781 0.9954 221125_WJC_METTL3_EV_vs_WT_F03.09159.09159.2 0.14 14-Jul K.AVVPEMEK.R "sp|P0CG22|DR4L1_HUMAN,sp|Q6PKH6|DR4L2_HUMAN,sp|Q9BTZ2|DHRS4_HUMAN,tr|H0YLE1|H0YLE1_HUMAN,tr|A0A087WSZ6|A0A087WSZ6_HUMAN,tr|A0A087WXI8|A0A087WXI8_HUMAN,tr|H0YKN3|H0YKN3_HUMAN" 7 901.4579 1.65 26459 9159 2 901.455543 451.7362 Putative dehydrogenase\reductase SDR family member 4-like 1 OS=Homo sapiens OX=9606 GN=DHRS4L1 PE=5 SV=1 4.53 2132.7 - 5.49E+06 - - - -2.6191 - 1.506 0.247 - 224.4 1 2 0 -0.0024 8 0 0 0 6.08E+08 3.69E+08 - - - 2.0995 0.9986 221125_WJC_METTL3_EV_vs_WT_F03.09165.09165.2 0.182 12-Jul R.FSGVPDR.F "sp|A0A075B6R9|KVD24_HUMAN,sp|A0A0C4DH68|KV224_HUMAN,sp|A2NJV5|KV229_HUMAN,sp|A0A075B6S2|KVD29_HUMAN,sp|A0A0A0MRZ7|KVD26_HUMAN" 5 776.3817 30.26 26461 9165 2 776.380862 389.1981 Probable non-functional immunoglobulin kappa variable 2D-24 OS=Homo sapiens OX=9606 GN=IGKV2D-24 PE=1 SV=1 5.84 2133.5 - 2.30E+06 - - - -1.0832 - 1.57 0.245 - 155.7 1 2 0 -0.0008 7 0 0 0 8.08E+07 2.67E+06 - - - 2.2796 0.9997 221125_WJC_METTL3_EV_vs_WT_F03.09166.09166.2 0.000435 18-Sep R.GTVVTGTLER.G sp|P49411|EFTU_HUMAN 1 1031.5611 1.47 26462 9166 2 1031.5614 516.7878 "Elongation factor Tu, mitochondrial OS=Homo sapiens OX=9606 GN=TUFM PE=1 SV=2" 6 2133.5 - 3.59E+06 - - - 0.2676 - 1.808 0.399 - 314.7 1 2 0 0.0003 10 0 0 0 1.19E+09 8.10E+08 - - - 3.641 0.998 221125_WJC_METTL3_EV_vs_WT_F03.09170.09170.2 0.0184 14-Aug K.AVVPEMEK[136.11].R "sp|P0CG22|DR4L1_HUMAN,sp|Q6PKH6|DR4L2_HUMAN,sp|Q9BTZ2|DHRS4_HUMAN,tr|H0YLE1|H0YLE1_HUMAN,tr|A0A087WSZ6|A0A087WSZ6_HUMAN,tr|A0A087WXI8|A0A087WXI8_HUMAN,tr|H0YKN3|H0YKN3_HUMAN" 7 909.4721 1.66 26464 9170 2 909.470286 455.7433 Putative dehydrogenase\reductase SDR family member 4-like 1 OS=Homo sapiens OX=9606 GN=DHRS4L1 PE=5 SV=1 4.53 2134 - 5.17E+06 - - - -1.999 - 1.434 0.311 - 278.4 1 2 0 -0.0018 8 0 0 0 6.19E+08 3.74E+08 - - - 2.4246 0.9902 221125_WJC_METTL3_EV_vs_WT_F03.09171.09171.2 0.0279 14-Sep K.NLVDNVAK.D "sp|Q9BZE4|GTPB4_HUMAN,tr|Q5T3R7|Q5T3R7_HUMAN" 2 871.4763 0.63 26465 9171 2 871.473326 436.7454 GTP-binding protein 4 OS=Homo sapiens OX=9606 GN=GTPBP4 PE=1 SV=3 5.84 2134 - 1.66E+06 - - - -3.4482 - 1.235 0.311 - 207.9 1 2 0 -0.003 8 0 0 0 4.03E+07 6.37E+07 - - - 1.9737 0.9718 221125_WJC_METTL3_EV_vs_WT_F03.09172.09172.2 0.213 14-Aug R.LSENVIDR.M "sp|Q9NX63|MIC19_HUMAN,tr|F8WAR4|F8WAR4_HUMAN,tr|C9JRZ6|C9JRZ6_HUMAN" 3 944.4927 1.85 26466 9172 2 944.491053 473.2536 MICOS complex subunit MIC19 OS=Homo sapiens OX=9606 GN=CHCHD3 PE=1 SV=1 4.37 2134.1 - 7.65E+07 - - - -1.7544 - 1.053 0.152 - 195 1 2 0 -0.0017 8 0 0 0 9.57E+08 5.17E+08 - - - 0.3189 0.9493 221125_WJC_METTL3_EV_vs_WT_F03.09174.09174.2 4.92 12-Jun R.TVIPINK.L "sp|P42357|HUTH_HUMAN,tr|F8W0V1|F8W0V1_HUMAN" 2 783.4854 9.1 26468 9174 2 783.484387 392.75 Histidine ammonia-lyase OS=Homo sapiens OX=9606 GN=HAL PE=1 SV=1 8.41 2134.3 - 1.03E+06 - - - -1.344 - 1.245 0.023 - 129.6 2 2 0 -0.0011 7 0 0 0 5.60E+07 6.16E+06 - - - -0.2296 0.999 221125_WJC_METTL3_EV_vs_WT_F03.09177.09177.2 0.183 12-Jul R.QIEYEYK[136.11].L "sp|P20700|LMNB1_HUMAN,tr|E9PBF6|E9PBF6_HUMAN,tr|A0A0D9SFE5|A0A0D9SFE5_HUMAN" 3 979.4742 0.99 26469 9177 2 979.473732 490.7444 Lamin-B1 OS=Homo sapiens OX=9606 GN=LMNB1 PE=1 SV=2 4.53 2134.6 - 7.46E+06 - - - -0.4911 - 1.374 0.315 - 285.2 1 2 0 -0.0005 7 0 0 0 2.21E+08 2.23E+08 - - - 2.3742 0.8578 221125_WJC_METTL3_EV_vs_WT_F03.09179.09179.2 2.92 14-Jul K.QFAPEYEK[136.11].L "sp|P13667|PDIA4_HUMAN,tr|C9JMN9|C9JMN9_HUMAN,tr|A0A499FI48|A0A499FI48_HUMAN" 3 1018.4851 0.41 26471 9179 2 1018.482438 510.2498 Protein disulfide-isomerase A4 OS=Homo sapiens OX=9606 GN=PDIA4 PE=1 SV=2 4.53 2134.8 - 1.42E+06 - - - -2.6255 - 1.182 0.027 - 170.9 2 2 0 -0.0027 8 0 0 0 1.53E+07 3.75E+07 - - - -0.3906 0.9855 221125_WJC_METTL3_EV_vs_WT_F03.09185.09185.2 0.202 14-Jul K.VC[160.03]NPIITK[136.11].L "sp|P11142|HSP7C_HUMAN,tr|E9PNE6|E9PNE6_HUMAN,tr|A8K7Q2|A8K7Q2_HUMAN,tr|E9PKE3|E9PKE3_HUMAN,tr|E9PS65|E9PS65_HUMAN" 5 951.5303 0.1 26473 9185 2 951.5297 476.7724 Heat shock cognate 71 kDa protein OS=Homo sapiens OX=9606 GN=HSPA8 PE=1 SV=1 8.19 2135.7 - 7.80E+07 - - - -0.618 - 1.414 0.043 - 160.7 1 2 0 -0.0006 8 0 0 0 1.96E+09 1.88E+10 - - - 0.4032 0.9997 221125_WJC_METTL3_EV_vs_WT_F03.09186.09186.2 0.00018 18-Sep R.GTVVTGTLER[166.11].G sp|P49411|EFTU_HUMAN 1 1041.5694 1.47 26474 9186 2 1041.568594 521.792 "Elongation factor Tu, mitochondrial OS=Homo sapiens OX=9606 GN=TUFM PE=1 SV=2" 6 2135.7 - 1.20E+07 - - - -0.7681 - 1.727 0.406 - 317 1 2 0 -0.0008 10 0 0 0 1.19E+09 8.10E+08 - - - 3.5646 0.9976 221125_WJC_METTL3_EV_vs_WT_F03.09187.09187.2 0.645 12-Jul R.QIEYEYK.L "sp|P20700|LMNB1_HUMAN,tr|E9PBF6|E9PBF6_HUMAN,tr|A0A0D9SFE5|A0A0D9SFE5_HUMAN" 3 971.46 0.99 26475 9187 2 971.459491 486.7373 Lamin-B1 OS=Homo sapiens OX=9606 GN=LMNB1 PE=1 SV=2 4.53 2135.8 - 9.09E+06 - - - -0.5373 - 1.204 0.278 - 207.6 1 2 0 -0.0005 7 0 0 0 2.21E+08 2.23E+08 - - - 1.6824 0.9954 221125_WJC_METTL3_EV_vs_WT_F03.09188.09188.2 0.259 14-Jun R.ILSGVVTK.M "sp|P62280|RS11_HUMAN,tr|M0QZC5|M0QZC5_HUMAN" 2 815.5117 0.89 26476 9188 2 815.510638 408.7631 40S ribosomal protein S11 OS=Homo sapiens OX=9606 GN=RPS11 PE=1 SV=3 8.75 2135.8 - 3.82E+06 - - - -1.2458 - 1.422 0.173 - 77.6 1 2 0 -0.001 8 0 0 0 1.23E+08 1.38E+08 - - - 1.3803 0.9995 221125_WJC_METTL3_EV_vs_WT_F03.09198.09198.2 0.000317 16-Aug R.VPPPPPIAR[166.11].A "sp|P07910|HNRPC_HUMAN,tr|B4DY08|B4DY08_HUMAN,tr|G3V575|G3V575_HUMAN,tr|G3V5V7|G3V5V7_HUMAN,tr|B2R5W2|B2R5W2_HUMAN,tr|G3V4C1|G3V4C1_HUMAN,tr|G3V576|G3V576_HUMAN,tr|G3V2D6|G3V2D6_HUMAN,tr|G3V4W0|G3V4W0_HUMAN,tr|G3V555|G3V555_HUMAN,tr|G3V2Q1|G3V2Q1_HUMAN" 11 952.5734 1.66 26480 9198 2 952.572094 477.294 Heterogeneous nuclear ribonucleoproteins C1\C2 OS=Homo sapiens OX=9606 GN=HNRNPC PE=1 SV=4 9.72 2137.1 - 5.26E+07 - - - -1.3259 - 1.65 0.383 - 263.1 1 2 0 -0.0013 9 0 0 0 3.74E+09 2.25E+09 - - - 3.3182 0.9319 221125_WJC_METTL3_EV_vs_WT_F03.09199.09199.2 3.88 12-Jul R.FEGLTQR[166.11].G sp|Q9Y2H1|ST38L_HUMAN 1 859.4427 2.14 26481 9199 2 859.441457 430.7286 Serine\threonine-protein kinase 38-like OS=Homo sapiens OX=9606 GN=STK38L PE=1 SV=3 6 2137.1 - 2.12E+06 - - - -1.4893 - 1.146 0.021 - 147.6 1 2 0 -0.0013 7 0 0 0 1.89E+08 8.83E+07 - - - -0.3725 0.8806 221125_WJC_METTL3_EV_vs_WT_F03.09206.09206.2 2.26 16-May R.YEAAVPDPR[166.11].E sp|O43505|B4GA1_HUMAN 1 1026.501 1 26486 9206 2 1026.50145 514.2578 "Beta-1,4-glucuronyltransferase 1 OS=Homo sapiens OX=9606 GN=B4GAT1 PE=1 SV=1" 4.37 2137.9 - 531919 - - - 0.4579 - 0.94 0.077 - 87.1 8 2 0 0.0005 9 0 0 0 3.11E+07 3.10E+07 - - - -0.9728 0.999 221125_WJC_METTL3_EV_vs_WT_F03.09207.09207.2 0.0917 16-Aug K.ILESVAEGR.A "sp|Q9UJV9|DDX41_HUMAN,tr|A0A499FJW5|A0A499FJW5_HUMAN,tr|H0YA06|H0YA06_HUMAN,tr|D6RGI7|D6RGI7_HUMAN" 4 972.524 1.04 26487 9207 2 972.523613 487.2693 Probable ATP-dependent RNA helicase DDX41 OS=Homo sapiens OX=9606 GN=DDX41 PE=1 SV=2 4.53 2138 - 6.99E+06 - - - -0.4082 - 1.605 0.273 - 180.4 1 2 0 -0.0004 9 0 0 0 2.22E+08 2.14E+08 - - - 2.426 0.9995 221125_WJC_METTL3_EV_vs_WT_F03.09209.09209.2 0.000403 14-Oct K.YAYYDTER[166.11].L "sp|O00303|EIF3F_HUMAN,tr|H0YDT6|H0YDT6_HUMAN" 2 1089.4643 1.25 26489 9209 2 1089.462802 545.7394 Eukaryotic translation initiation factor 3 subunit F OS=Homo sapiens OX=9606 GN=EIF3F PE=1 SV=1 4.37 2138.1 - 1.05E+06 - - - -1.3383 - 1.49 0.426 - 313.7 1 2 0 -0.0015 8 0 0 0 7.78E+07 6.21E+07 - - - 3.3897 0.9998 221125_WJC_METTL3_EV_vs_WT_F03.09214.09214.2 0.0016 16-Sep R.FTEYETQVK[136.11].V "sp|Q13148|TADBP_HUMAN,tr|A0A087WX67|A0A087WX67_HUMAN,tr|A0A087WX29|A0A087WX29_HUMAN,tr|G3V162|G3V162_HUMAN,tr|A0A087WV68|A0A087WV68_HUMAN,tr|A0A087WXV3|A0A087WXV3_HUMAN,tr|A0A087WYY0|A0A087WYY0_HUMAN,tr|K7EN94|K7EN94_HUMAN,tr|A0A0A0N0M3|A0A0A0N0M3_HUMAN,tr|A0A087WW61|A0A087WW61_HUMAN,tr|B1AKP7|B1AKP7_HUMAN,tr|K7EJM5|K7EJM5_HUMAN,tr|A0A087WXQ5|A0A087WXQ5_HUMAN,tr|A0A087X260|A0A087X260_HUMAN" 14 1151.559 1.4 26492 9214 2 1151.558463 576.7868 TAR DNA-binding protein 43 OS=Homo sapiens OX=9606 GN=TARDBP PE=1 SV=1 4.53 2138.7 - 3.22E+07 - - - -0.4707 - 1.731 0.477 - 236 1 2 0 -0.0005 9 0 0 0 1.20E+09 8.54E+08 - - - 4.1514 0.9992 221125_WJC_METTL3_EV_vs_WT_F03.09215.09215.2 0.00341 14-Jul R.EFIQEPAK.N "sp|O14744|ANM5_HUMAN,tr|C9JSX3|C9JSX3_HUMAN,tr|G3V580|G3V580_HUMAN,tr|G3V2L6|G3V2L6_HUMAN,tr|G3V5L5|G3V5L5_HUMAN" 5 960.4916 3.01 26493 9215 2 960.491061 481.2531 Protein arginine N-methyltransferase 5 OS=Homo sapiens OX=9606 GN=PRMT5 PE=1 SV=4 4.53 2138.7 - 1.74E+07 - - - -0.6101 - 1.325 0.374 - 187.9 1 2 0 -0.0006 8 0 0 0 3.67E+09 1.22E+09 - - - 2.6519 0.9991 221125_WJC_METTL3_EV_vs_WT_F03.09216.09216.2 0.00419 14-Jul R.EFIQEPAK[136.11].N "sp|O14744|ANM5_HUMAN,tr|C9JSX3|C9JSX3_HUMAN,tr|G3V580|G3V580_HUMAN,tr|G3V2L6|G3V2L6_HUMAN,tr|G3V5L5|G3V5L5_HUMAN" 5 968.5058 3.01 26494 9216 2 968.506911 485.2602 Protein arginine N-methyltransferase 5 OS=Homo sapiens OX=9606 GN=PRMT5 PE=1 SV=4 4.53 2138.8 - 7.55E+06 - - - 1.0986 - 1.501 0.335 - 178.8 1 2 0 0.0011 8 0 0 0 3.67E+09 1.22E+09 - - - 2.7398 0.9994 221125_WJC_METTL3_EV_vs_WT_F03.09217.09217.2 0.0145 14-Aug R.YIATITDK.E "sp|O75179|ANR17_HUMAN,sp|Q8IWZ3|ANKH1_HUMAN,tr|E9PDP5|E9PDP5_HUMAN,tr|H0YM23|H0YM23_HUMAN,tr|H3BLS9|H3BLS9_HUMAN,tr|H0Y4P6|H0Y4P6_HUMAN,tr|H0YLQ3|H0YLQ3_HUMAN,tr|H7C2F5|H7C2F5_HUMAN" 8 923.4964 1.07 26495 9217 2 923.496073 462.7555 Ankyrin repeat domain-containing protein 17 OS=Homo sapiens OX=9606 GN=ANKRD17 PE=1 SV=3 5.83 2138.9 - 1.92E+06 - - - -0.3519 - 1.551 0.342 - 196.2 1 2 0 -0.0003 8 0 0 0 9.10E+07 8.46E+07 - - - 2.8906 0.9997 221125_WJC_METTL3_EV_vs_WT_F03.09218.09218.2 0.000411 14-Aug K.YAYYDTER.L "sp|O00303|EIF3F_HUMAN,tr|H0YDT6|H0YDT6_HUMAN" 2 1079.456 1.25 26496 9218 2 1079.454908 540.7353 Eukaryotic translation initiation factor 3 subunit F OS=Homo sapiens OX=9606 GN=EIF3F PE=1 SV=1 4.37 2139 - 1.69E+06 - - - -1.0024 - 1.384 0.522 - 202.2 1 2 0 -0.0011 8 0 0 0 7.78E+07 6.21E+07 - - - 3.8763 0.9995 221125_WJC_METTL3_EV_vs_WT_F03.09219.09219.2 0.00878 14-Sep K.K[136.11]IFVGGIK[136.11].E "sp|Q32P51|RA1L2_HUMAN,sp|P51991|ROA3_HUMAN,sp|Q13151|ROA0_HUMAN,sp|P09651|ROA1_HUMAN,sp|P22626|ROA2_HUMAN,tr|A0A7I2YQN4|A0A7I2YQN4_HUMAN,tr|A0A7I2YQX9|A0A7I2YQX9_HUMAN,tr|A0A7I2V4N0|A0A7I2V4N0_HUMAN,tr|A0A024RA28|A0A024RA28_HUMAN,tr|A0A7I2V4N1|A0A7I2V4N1_HUMAN,tr|A0A7I2V5D8|A0A7I2V5D8_HUMAN,tr|A0A7I2V2R3|A0A7I2V2R3_HUMAN,tr|A0A7I2V4I6|A0A7I2V4I6_HUMAN,tr|F8VZ49|F8VZ49_HUMAN,tr|A0A7I2V3R8|A0A7I2V3R8_HUMAN,tr|A0A087WUI2|A0A087WUI2_HUMAN,tr|A0A7I2V4S4|A0A7I2V4S4_HUMAN,tr|F8VTQ5|F8VTQ5_HUMAN,tr|F8W6I7|F8W6I7_HUMAN,tr|A0A7I2V2L6|A0A7I2V2L6_HUMAN,tr|A0A7I2V4J6|A0A7I2V4J6_HUMAN,tr|A0A7I2V323|A0A7I2V323_HUMAN,tr|A0A7I2V3W0|A0A7I2V3W0_HUMAN,tr|A0A7I2V4G0|A0A7I2V4G0_HUMAN,tr|A0A7I2V5U9|A0A7I2V5U9_HUMAN,tr|A0A2R8Y4L2|A0A2R8Y4L2_HUMAN,tr|A0A7I2V402|A0A7I2V402_HUMAN,tr|A0A7I2V3P1|A0A7I2V3P1_HUMAN,tr|A0A7I2V3P7|A0A7I2V3P7_HUMAN" 29 876.5768 1.19 26497 9219 2 876.575407 439.2957 Heterogeneous nuclear ribonucleoprotein A1-like 2 OS=Homo sapiens OX=9606 GN=HNRNPA1L2 PE=2 SV=2 10 2139.1 - 1.33E+06 - - - -1.5595 - 1.871 0.361 - 314.8 1 2 0 -0.0014 8 0 0 0 2.47E+08 2.09E+08 - - - 3.5963 0.9993 221125_WJC_METTL3_EV_vs_WT_F03.09220.09220.2 0.0103 12-Jul K.LFDEEGR.K "sp|Q6ZU65|UBN2_HUMAN,tr|H7C4P8|H7C4P8_HUMAN" 2 864.3977 1.05 26498 9220 2 864.396652 433.2061 Ubinuclein-2 OS=Homo sapiens OX=9606 GN=UBN2 PE=1 SV=2 4.14 2139.2 - 972499 - - - -1.2668 - 1.697 0.31 - 146.4 1 2 0 -0.0011 7 0 0 0 5.45E+07 5.20E+07 - - - 3.006 0.9998 221125_WJC_METTL3_EV_vs_WT_F03.09227.09227.2 5.58E-06 22-Dec R.LVESDAEAEAVR.E "sp|Q9BZJ0|CRNL1_HUMAN,tr|Q5JY65|Q5JY65_HUMAN" 2 1287.6307 1.51 26503 9227 2 1287.629255 644.8226 Crooked neck-like protein 1 OS=Homo sapiens OX=9606 GN=CRNKL1 PE=1 SV=4 4 2139.9 - 467351 - - - -1.0912 - 2.405 0.4 - 459.8 1 2 0 -0.0014 12 0 0 0 9.00E+07 5.98E+07 - - - 4.3039 0.9958 221125_WJC_METTL3_EV_vs_WT_F03.09228.09228.2 0.056 20-Aug K.LSAMMGAVAEK[136.11].K "sp|Q86U44|MTA70_HUMAN,tr|F5H6D8|F5H6D8_HUMAN,tr|H0YFV6|H0YFV6_HUMAN,tr|B4DTN4|B4DTN4_HUMAN" 4 1114.5606 0.07 26504 9228 2 1114.56201 558.2876 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 6 2140.1 - 375154 - - - 1.2633 - 1.599 0.166 - 141.3 1 2 0 0.0014 11 0 0 0 3.92E+05 5.49E+06 - - - 1.5364 0.9748 221125_WJC_METTL3_EV_vs_WT_F03.09231.09231.2 24.4 14-Jun K.KIFVGGIK.E "sp|Q32P51|RA1L2_HUMAN,sp|P51991|ROA3_HUMAN,sp|Q13151|ROA0_HUMAN,sp|P09651|ROA1_HUMAN,sp|P22626|ROA2_HUMAN,tr|A0A7I2YQN4|A0A7I2YQN4_HUMAN,tr|A0A7I2YQX9|A0A7I2YQX9_HUMAN,tr|A0A7I2V4N0|A0A7I2V4N0_HUMAN,tr|A0A024RA28|A0A024RA28_HUMAN,tr|A0A7I2V4N1|A0A7I2V4N1_HUMAN,tr|A0A7I2V5D8|A0A7I2V5D8_HUMAN,tr|A0A7I2V2R3|A0A7I2V2R3_HUMAN,tr|A0A7I2V4I6|A0A7I2V4I6_HUMAN,tr|F8VZ49|F8VZ49_HUMAN,tr|A0A7I2V3R8|A0A7I2V3R8_HUMAN,tr|A0A087WUI2|A0A087WUI2_HUMAN,tr|A0A7I2V4S4|A0A7I2V4S4_HUMAN,tr|F8VTQ5|F8VTQ5_HUMAN,tr|F8W6I7|F8W6I7_HUMAN,tr|A0A7I2V2L6|A0A7I2V2L6_HUMAN,tr|A0A7I2V4J6|A0A7I2V4J6_HUMAN,tr|A0A7I2V323|A0A7I2V323_HUMAN,tr|A0A7I2V3W0|A0A7I2V3W0_HUMAN,tr|A0A7I2V4G0|A0A7I2V4G0_HUMAN,tr|A0A7I2V5U9|A0A7I2V5U9_HUMAN,tr|A0A2R8Y4L2|A0A2R8Y4L2_HUMAN,tr|A0A7I2V402|A0A7I2V402_HUMAN,tr|A0A7I2V3P1|A0A7I2V3P1_HUMAN,tr|A0A7I2V3P7|A0A7I2V3P7_HUMAN" 29 860.5484 1.19 26505 9231 2 860.547363 431.2815 Heterogeneous nuclear ribonucleoprotein A1-like 2 OS=Homo sapiens OX=9606 GN=HNRNPA1L2 PE=2 SV=2 10 2140.5 - 2.13E+06 - - - -1.1748 - 1.182 0.085 - 110.8 1 2 0 -0.001 8 0 0 0 2.47E+08 2.09E+08 - - - 0.1728 0.9873 221125_WJC_METTL3_EV_vs_WT_F03.09233.09233.2 0.821 12-May K.LVTDLTK.V "sp|P02768|ALBU_HUMAN,tr|B7WNR0|B7WNR0_HUMAN,tr|H0YA55|H0YA55_HUMAN,tr|A0A0C4DGB6|A0A0C4DGB6_HUMAN,tr|D6RHD5|D6RHD5_HUMAN,tr|C9JKR2|C9JKR2_HUMAN" 6 788.4644 8.46 26507 9233 2 788.463769 395.2395 Albumin OS=Homo sapiens OX=9606 GN=ALB PE=1 SV=2 5.84 2140.6 - 2.78E+06 - - - -0.7622 - 1.228 0.159 - 71 6 2 0 -0.0006 7 0 0 0 7.04E+07 8.31E+06 - - - 0.5184 0.9869 221125_WJC_METTL3_EV_vs_WT_F03.09234.09234.2 0.864 14-Jun K.QFAPEYEK.L "sp|P13667|PDIA4_HUMAN,tr|C9JMN9|C9JMN9_HUMAN,tr|A0A499FI48|A0A499FI48_HUMAN" 3 1010.4709 0.39 26508 9234 2 1010.470409 506.2427 Protein disulfide-isomerase A4 OS=Homo sapiens OX=9606 GN=PDIA4 PE=1 SV=2 4.53 2140.7 - 505104 - - - -0.4978 - 1.102 0.152 - 68.9 1 2 0 -0.0005 8 0 0 0 1.45E+07 3.73E+07 - - - 0.4564 0.9985 221125_WJC_METTL3_EV_vs_WT_F03.09236.09236.2 0.376 16-Jun R.VPPPPPIAR.A "sp|P07910|HNRPC_HUMAN,tr|B4DY08|B4DY08_HUMAN,tr|G3V575|G3V575_HUMAN,tr|G3V5V7|G3V5V7_HUMAN,tr|B2R5W2|B2R5W2_HUMAN,tr|G3V4C1|G3V4C1_HUMAN,tr|G3V576|G3V576_HUMAN,tr|G3V2D6|G3V2D6_HUMAN,tr|G3V4W0|G3V4W0_HUMAN,tr|G3V555|G3V555_HUMAN,tr|G3V2Q1|G3V2Q1_HUMAN" 11 942.5651 1.54 26509 9236 2 942.56495 472.2898 Heterogeneous nuclear ribonucleoproteins C1\C2 OS=Homo sapiens OX=9606 GN=HNRNPC PE=1 SV=4 9.72 2140.9 - 8.45E+07 - - - -0.1453 - 1.292 0.302 - 131.4 1 2 0 -0.0001 9 0 0 0 8.29E+09 5.37E+09 - - - 2.0127 0.8316 221125_WJC_METTL3_EV_vs_WT_F03.09238.09238.2 1.06 14-Jun V.PPPPPIAR.A "sp|P07910|HNRPC_HUMAN,tr|B4DY08|B4DY08_HUMAN,tr|G3V575|G3V575_HUMAN,tr|G3V5V7|G3V5V7_HUMAN,tr|B2R5W2|B2R5W2_HUMAN,tr|G3V4C1|G3V4C1_HUMAN,tr|G3V576|G3V576_HUMAN,tr|G3V2D6|G3V2D6_HUMAN,tr|G3V4W0|G3V4W0_HUMAN,tr|G3V555|G3V555_HUMAN,tr|G3V2Q1|G3V2Q1_HUMAN" 11 843.4967 1.59 26510 9238 2 843.496003 422.7556 Heterogeneous nuclear ribonucleoproteins C1\C2 OS=Homo sapiens OX=9606 GN=HNRNPC PE=1 SV=4 10.18 2141.1 - 2.07E+06 - - - -0.7943 - 1.399 0.21 - 141.6 2 1 0 -0.0007 8 0 0 0 1.58E+08 9.94E+07 - - - 1.47 0.9981 221125_WJC_METTL3_EV_vs_WT_F03.09239.09239.2 0.000148 22-Nov R.LVESDAEAEAVR[166.11].E "sp|Q9BZJ0|CRNL1_HUMAN,tr|Q5JY65|Q5JY65_HUMAN" 2 1297.6389 1.51 26511 9239 2 1297.633978 649.8267 Crooked neck-like protein 1 OS=Homo sapiens OX=9606 GN=CRNKL1 PE=1 SV=4 4 2141.3 - 720405 - - - -3.8162 - 2.106 0.394 - 191.3 1 2 0 -0.005 12 0 0 0 9.00E+07 5.98E+07 - - - 3.9092 0.9995 221125_WJC_METTL3_EV_vs_WT_F03.09253.09253.2 0.0118 14-Aug K.VVEIVDEK.V "sp|Q6PKG0|LARP1_HUMAN,tr|A0A0B4J210|A0A0B4J210_HUMAN,tr|H0YBW1|H0YBW1_HUMAN,tr|H0YC73|H0YC73_HUMAN,tr|E5RH50|E5RH50_HUMAN" 5 929.507 1.56 26520 9253 2 929.506973 465.7608 La-related protein 1 OS=Homo sapiens OX=9606 GN=LARP1 PE=1 SV=2 4.14 2142.7 - 6.15E+06 - - - 0.0108 - 1.789 0.314 - 227.9 1 2 0 0 8 0 0 0 2.85E+08 1.83E+08 - - - 3.1145 0.8563 221125_WJC_METTL3_EV_vs_WT_F03.09255.09255.2 0.267 14-May R.GLLQDDAH.P "sp|Q86U44|MTA70_HUMAN,tr|F5H6D8|F5H6D8_HUMAN,tr|H0YFV6|H0YFV6_HUMAN,tr|B4DTN4|B4DTN4_HUMAN" 4 867.4086 - 26522 9255 2 867.408493 434.7116 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 4.2 2142.9 - 874885 - - - -0.1764 - 1.247 0.265 - 56.6 2 1 0 -0.0002 8 0 0 0 - - - - - 1.5295 0.9322 221125_WJC_METTL3_EV_vs_WT_F03.09263.09263.2 4.09 12-Jun K.LDPITGR[166.11].S "sp|Q14103|HNRPD_HUMAN,tr|H0Y8G5|H0Y8G5_HUMAN,tr|D6RF44|D6RF44_HUMAN,tr|D6RD83|D6RD83_HUMAN,tr|D6RBQ9|D6RBQ9_HUMAN,tr|D6RAF8|D6RAF8_HUMAN,tr|H0YA96|H0YA96_HUMAN" 7 780.4369 1.39 26525 9263 2 780.435705 391.2257 Heterogeneous nuclear ribonucleoprotein D0 OS=Homo sapiens OX=9606 GN=HNRNPD PE=1 SV=1 5.84 2143.9 - 1.75E+06 - - - -1.5607 - 1.03 0.071 - 169.6 1 2 0 -0.0012 7 0 0 0 2.26E+08 1.62E+08 - - - -0.3413 0.9766 221125_WJC_METTL3_EV_vs_WT_F03.09266.09266.2 3.75 12-Jul K.LQVALQR.L "sp|Q8IYM9|TRI22_HUMAN,tr|H7BZD3|H7BZD3_HUMAN,tr|C9J060|C9J060_HUMAN,tr|C9JIU5|C9JIU5_HUMAN" 4 826.5025 27.25 26528 9266 2 826.501409 414.2585 E3 ubiquitin-protein ligase TRIM22 OS=Homo sapiens OX=9606 GN=TRIM22 PE=1 SV=1 9.75 2144.2 - 1.02E+06 - - - -1.3043 - 1.286 0.058 - 145.4 1 2 0 -0.0011 7 0 0 0 2.33E+07 8.55E+05 - - - 0.2661 0.9985 221125_WJC_METTL3_EV_vs_WT_F03.09269.09269.2 0.0126 14-Aug R.VPSFAAGR[166.11].V sp|O00425|IF2B3_HUMAN 1 813.4373 1.83 26529 9269 2 813.439293 407.7259 Insulin-like growth factor 2 mRNA-binding protein 3 OS=Homo sapiens OX=9606 GN=IGF2BP3 PE=1 SV=2 9.72 2144.6 - 2.92E+06 - - - 2.503 - 1.637 0.35 - 230.6 1 2 0 0.002 8 0 0 0 6.28E+08 3.43E+08 - - - 3.1119 0.9996 221125_WJC_METTL3_EV_vs_WT_F03.09278.09278.2 0.00261 16-Aug R.YGLVGPNGK[136.11].G "sp|Q8NE71|ABCF1_HUMAN,tr|Q5STZ8|Q5STZ8_HUMAN,tr|H0YGW7|H0YGW7_HUMAN" 3 911.4956 1.04 26534 9278 2 911.496495 456.7551 ATP-binding cassette sub-family F member 1 OS=Homo sapiens OX=9606 GN=ABCF1 PE=1 SV=2 8.59 2145.7 - 2.66E+06 - - - 0.9633 - 1.776 0.377 - 176.7 1 2 0 0.0009 9 0 0 0 8.23E+07 7.94E+07 - - - 3.4869 0.9985 221125_WJC_METTL3_EV_vs_WT_F03.09284.09284.2 0.0757 18-Sep K.AIEEQMVAAK[136.11].D "sp|Q9H0A0|NAT10_HUMAN,tr|A0A087WV29|A0A087WV29_HUMAN" 2 1096.5678 1.08 26536 9284 2 1096.565575 549.2912 RNA cytidine acetyltransferase OS=Homo sapiens OX=9606 GN=NAT10 PE=1 SV=2 4.53 2146.5 - 705961 - - - -2.0254 - 1.657 0.309 - 204.6 1 2 0 -0.0022 10 0 0 0 4.50E+07 4.18E+07 - - - 2.7322 0.9993 221125_WJC_METTL3_EV_vs_WT_F03.09286.09286.2 0.00167 20-Jul R.LAPEYEAAATR.L "sp|P30101|PDIA3_HUMAN,tr|H7BZJ3|H7BZJ3_HUMAN" 2 1190.5932 0.86 26538 9286 2 1190.591339 596.3039 Protein disulfide-isomerase A3 OS=Homo sapiens OX=9606 GN=PDIA3 PE=1 SV=4 4.53 2146.7 - 383286 - - - -1.5228 - 1.607 0.377 - 159.7 1 2 0 -0.0018 11 0 0 0 1.06E+08 1.23E+08 - - - 3.1082 0.9941 221125_WJC_METTL3_EV_vs_WT_F03.09296.09296.2 0.0377 18-Sep R.VILDEGHAIR.N "sp|Q14527|HLTF_HUMAN,tr|H7C5K0|H7C5K0_HUMAN,tr|A0A0C4DGA6|A0A0C4DGA6_HUMAN" 3 1121.6193 5 26543 9296 2 1121.613895 561.8169 Helicase-like transcription factor OS=Homo sapiens OX=9606 GN=HLTF PE=1 SV=2 5.32 2147.9 - 695116 - - - -4.8252 - 1.87 0.355 - 246.9 1 2 0 -0.0054 10 0 0 0 3.33E+07 6.67E+06 - - - 3.4085 0.9995 221125_WJC_METTL3_EV_vs_WT_F03.09298.09298.2 0.00725 14-Aug K.VVEIVDEK[136.11].V "sp|Q6PKG0|LARP1_HUMAN,tr|A0A0B4J210|A0A0B4J210_HUMAN,tr|H0YBW1|H0YBW1_HUMAN,tr|H0YC73|H0YC73_HUMAN,tr|E5RH50|E5RH50_HUMAN" 5 937.5212 1.56 26544 9298 2 937.520578 469.7679 La-related protein 1 OS=Homo sapiens OX=9606 GN=LARP1 PE=1 SV=2 4.14 2148.1 - 2.27E+06 - - - -0.624 - 1.819 0.311 - 232.2 1 2 0 -0.0006 8 0 0 0 2.85E+08 1.83E+08 - - - 3.1423 0.9988 221125_WJC_METTL3_EV_vs_WT_F03.09301.09301.2 0.00074 16-Sep R.MLLQSSEGR[166.11].C "sp|O75643|U520_HUMAN,tr|A0A494C1A5|A0A494C1A5_HUMAN" 2 1029.5152 1.41 26546 9301 2 1029.513777 515.7649 U5 small nuclear ribonucleoprotein 200 kDa helicase OS=Homo sapiens OX=9606 GN=SNRNP200 PE=1 SV=2 5.75 2148.4 - 2.49E+06 - - - -1.4308 - 1.802 0.246 - 334 1 2 0 -0.0015 9 0 0 0 1.43E+08 1.01E+08 - - - 2.5612 0.9997 221125_WJC_METTL3_EV_vs_WT_F03.09304.09304.2 0.000144 18-Dec K.VLDNAIETEK[136.11].M "sp|Q01082|SPTB2_HUMAN,tr|A0A087WUZ3|A0A087WUZ3_HUMAN,tr|F8W6C1|F8W6C1_HUMAN" 3 1138.5961 0.001 26547 9304 2 1138.5935 570.3053 "Spectrin beta chain, non-erythrocytic 1 OS=Homo sapiens OX=9606 GN=SPTBN1 PE=1 SV=2" 4.14 2148.8 - 1.25E+06 - - - -2.3002 - 2.31 0.52 - 418.1 1 2 0 -0.0026 10 0 0 0 0.00E+00 8.54E+07 - - - 5.2179 0.9987 221125_WJC_METTL3_EV_vs_WT_F03.09306.09306.2 0.0148 18-Aug K.SLESTTLTEK.E "sp|Q16527|CSRP2_HUMAN,tr|F8VQR7|F8VQR7_HUMAN,tr|F8VW96|F8VW96_HUMAN" 3 1107.5659 0.62 26548 9306 2 1107.565643 554.7902 Cysteine and glycine-rich protein 2 OS=Homo sapiens OX=9606 GN=CSRP2 PE=1 SV=3 4.53 2149 - 696278 - - - -0.2627 - 1.355 0.302 - 155.5 1 2 0 -0.0003 10 0 0 0 4.86E+07 7.89E+07 - - - 2.1195 0.987 221125_WJC_METTL3_EV_vs_WT_F03.09307.09307.2 0.815 18-Dec R.PGGYGYGYGR[166.11].S sp|P98179|RBM3_HUMAN 1 1055.47 1.37 26549 9307 2 1055.471324 528.7423 RNA-binding protein 3 OS=Homo sapiens OX=9606 GN=RBM3 PE=1 SV=1 8.9 2149.1 - 1.12E+06 - - - 1.2412 - 2.152 0.453 - 742 1 1 0 0.0013 10 0 0 0 2.24E+08 1.63E+08 - - - 4.5257 1 221125_WJC_METTL3_EV_vs_WT_F03.09308.09308.2 2.62E-06 16-Oct R.YDDMATC[160.03]MK[136.11].A "sp|P27348|1433T_HUMAN,tr|E9PG15|E9PG15_HUMAN" 2 1141.4334 0.63 26550 9308 2 1141.432095 571.724 14-3-3 protein theta OS=Homo sapiens OX=9606 GN=YWHAQ PE=1 SV=1 4.21 2149.2 - 1.07E+06 - - - -1.1021 - 1.927 0.656 - 292 1 2 0 -0.0013 9 0 0 0 2.68E+07 4.25E+07 - - - 5.7836 0.9995 221125_WJC_METTL3_EV_vs_WT_F03.09311.09311.2 0.000503 13/18 K.VETTEDLVAK.L sp|P38117|ETFB_HUMAN 1 1103.571 1.75 26551 9311 2 1103.567939 552.7928 Electron transfer flavoprotein subunit beta OS=Homo sapiens OX=9606 GN=ETFB PE=1 SV=3 4.14 2149.6 - 1.29E+06 - - - -2.7918 - 2.233 0.473 - 348.6 1 2 0 -0.0031 10 0 0 0 5.92E+08 3.38E+08 - - - 4.776 0.8575 221125_WJC_METTL3_EV_vs_WT_F03.09318.09318.2 3.46 22-Jul K.DTIDVLNQISEK.Q "sp|Q5VT06|CE350_HUMAN,tr|H0Y7F7|H0Y7F7_HUMAN,tr|Q5T2X4|Q5T2X4_HUMAN" 3 1373.7038 999 26555 9318 2 1373.710047 687.8592 Centrosome-associated protein 350 OS=Homo sapiens OX=9606 GN=CEP350 PE=1 SV=1 4.03 2150.4 - 673220 - - - 4.5294 - 1.191 0.138 - 112.1 1 2 0 0.0062 12 0 0 0 8.39E+06 0.00E+00 - - - 0.5182 1 221125_WJC_METTL3_EV_vs_WT_F03.09322.09322.2 9.35E-07 14/18 K.VETTEDLVAK[136.11].L sp|P38117|ETFB_HUMAN 1 1111.5852 1.75 26557 9322 2 1111.584706 556.7999 Electron transfer flavoprotein subunit beta OS=Homo sapiens OX=9606 GN=ETFB PE=1 SV=3 4.14 2150.8 - 1.96E+06 - - - -0.4624 - 2.749 0.544 - 707.2 1 2 0 -0.0005 10 0 0 0 5.91E+08 3.38E+08 - - - 5.8815 0.9997 221125_WJC_METTL3_EV_vs_WT_F03.09324.09324.2 0.000112 14-Jul K.EHC[160.03]LVGVK[136.11].G sp|Q86U44|MTA70_HUMAN 1 948.4942 1.27 26559 9324 2 948.493487 475.2544 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 6.83 2150.9 - 1.95E+06 - - - -0.7907 - 1.477 0.459 - 263.1 1 2 0 -0.0008 8 0 0 0 1.09E+08 8.55E+07 - - - 3.6072 0.9771 221125_WJC_METTL3_EV_vs_WT_F03.09327.09327.2 0.0017 18-Aug K.ENAGEDPGLA.R sp|P81605|DCD_HUMAN 1 971.4196 - 26560 9327 2 971.420408 486.7171 Dermcidin OS=Homo sapiens OX=9606 GN=DCD PE=1 SV=2 3.57 2151.3 - 3.39E+06 - - - 0.8277 - 1.262 0.517 - 80.5 1 1 0 0.0008 10 0 0 0 - - - - - 3.5088 0.9623 221125_WJC_METTL3_EV_vs_WT_F03.09331.09331.2 0.0315 12-Jun R.LSETDFK[136.11].V "sp|Q15007|FL2D_HUMAN,tr|A0A087X1R4|A0A087X1R4_HUMAN" 2 846.4214 1.21 26562 9331 2 846.418614 424.218 Pre-mRNA-splicing regulator WTAP OS=Homo sapiens OX=9606 GN=WTAP PE=1 SV=2 4.37 2151.9 - 6.58E+06 - - - -3.3494 - 1.533 0.086 - 110.9 2 2 0 -0.0028 7 0 0 0 2.43E+08 2.01E+08 - - - 0.8945 0.9863 221125_WJC_METTL3_EV_vs_WT_F03.09332.09332.2 1.65E-06 18-Nov K.VIDQQNGLYR[166.11].C sp|P27694|RFA1_HUMAN 1 1214.6283 1.31 26563 9332 2 1214.62017 608.3214 Replication protein A 70 kDa DNA-binding subunit OS=Homo sapiens OX=9606 GN=RPA1 PE=1 SV=2 5.81 2152 - 663326 - - - -6.6983 - 2.07 0.389 - 299.6 1 2 0 -0.0081 10 0 0 0 5.67E+08 4.34E+08 - - - 3.9424 0.9993 221125_WJC_METTL3_EV_vs_WT_F03.09333.09333.2 0.000474 18-Nov R.ASAVSELSPR[166.11].E "sp|Q9Y2W1|TR150_HUMAN,tr|A0A3B3ITZ9|A0A3B3ITZ9_HUMAN" 2 1025.5381 2.9 26564 9333 2 1025.538751 513.7763 Thyroid hormone receptor-associated protein 3 OS=Homo sapiens OX=9606 GN=THRAP3 PE=1 SV=2 6.05 2152.1 - 2.40E+06 - - - 0.6406 - 2.119 0.23 - 498.2 1 2 0 0.0007 10 0 0 0 3.55E+09 1.22E+09 - - - 2.8357 0.9959 221125_WJC_METTL3_EV_vs_WT_F03.09336.09336.2 0.246 16-Jul K.MMASGLTER[166.11].V sp|Q9UG63|ABCF2_HUMAN 1 1004.4659 0.03 26565 9336 2 1004.464737 503.2402 ATP-binding cassette sub-family F member 2 OS=Homo sapiens OX=9606 GN=ABCF2 PE=1 SV=2 5.75 2152.4 - 340684 - - - -1.115 - 1.298 0.219 - 148.3 1 2 0 -0.0011 9 0 0 0 6.52E+06 2.29E+08 - - - 1.4128 0.9998 221125_WJC_METTL3_EV_vs_WT_F03.09339.09339.2 0.00458 16-Nov R.IEANEALVK.A sp|P30049|ATPD_HUMAN 1 985.5444 2.14 26566 9339 2 985.543453 493.7795 "ATP synthase subunit delta, mitochondrial OS=Homo sapiens OX=9606 GN=ATP5F1D PE=1 SV=2" 4.53 2152.8 - 8.89E+06 - - - -0.9721 - 2.081 0.392 - 330.3 1 2 0 -0.001 9 0 0 0 5.44E+08 2.54E+08 - - - 4.0562 0.9996 221125_WJC_METTL3_EV_vs_WT_F03.09342.09342.2 0.00189 20-Dec R.VAAAMENPNLR.E sp|Q9H5X1|CIA2A_HUMAN 1 1184.5972 1.15 26568 9342 2 1184.596203 593.3059 Cytosolic iron-sulfur assembly component 2A OS=Homo sapiens OX=9606 GN=CIAO2A PE=1 SV=1 5.97 2153.2 - 907713 - - - -0.8349 - 2.028 0.329 - 488.2 1 2 0 -0.001 11 0 0 0 2.38E+07 2.08E+07 - - - 3.3834 0.9929 221125_WJC_METTL3_EV_vs_WT_F03.09345.09345.2 0.00157 22-Dec R.FIAEEAAASGAK.C "sp|O14732|IMPA2_HUMAN,tr|K7EL65|K7EL65_HUMAN,tr|K7ELF8|K7ELF8_HUMAN" 3 1163.5823 7.99 26569 9345 2 1163.587751 582.7984 Inositol monophosphatase 2 OS=Homo sapiens OX=9606 GN=IMPA2 PE=1 SV=1 4.53 2153.6 - 844118 - - - 4.7251 - 1.516 0.41 - 373 1 2 0 0.0055 12 0 0 0 3.73E+07 4.67E+06 - - - 3.1623 0.9987 221125_WJC_METTL3_EV_vs_WT_F03.09348.09348.2 0.000877 18-Oct K.VIDQQNGLYR.C sp|P27694|RFA1_HUMAN 1 1204.62 1.31 26570 9348 2 1204.624125 603.3173 Replication protein A 70 kDa DNA-binding subunit OS=Homo sapiens OX=9606 GN=RPA1 PE=1 SV=2 5.81 2153.9 - 2.34E+06 - - - 3.3944 - 2.039 0.409 - 382.9 1 2 0 0.0041 10 0 0 0 5.67E+08 4.34E+08 - - - 4.0493 0.8389 221125_WJC_METTL3_EV_vs_WT_F03.09351.09351.2 0.202 14-Aug R.FIMESGAK[136.11].G "sp|P23396|RS3_HUMAN,tr|H0YEU2|H0YEU2_HUMAN,tr|E9PL09|E9PL09_HUMAN" 3 889.4459 0.51 26572 9351 2 889.441183 445.7302 40S ribosomal protein S3 OS=Homo sapiens OX=9606 GN=RPS3 PE=1 SV=2 6 2154.2 - 988790 - - - -5.2909 - 1.079 0.203 - 126.4 1 2 0 -0.0047 8 0 0 0 8.99E+07 1.76E+08 - - - 0.7682 0.9887 221125_WJC_METTL3_EV_vs_WT_F03.09355.09355.2 0.299 16-Jun R.ELAEQELEK[136.11].Q sp|Q15149|PLEC_HUMAN 1 1095.5539 1.6 26574 9355 2 1095.554323 548.7842 Plectin OS=Homo sapiens OX=9606 GN=PLEC PE=1 SV=3 4.09 2154.7 - 503094 - - - 0.3679 - 1.222 0.129 - 101.8 1 2 0 0.0004 9 0 0 0 3.56E+07 2.22E+07 - - - 0.5737 0.9992 221125_WJC_METTL3_EV_vs_WT_F03.09360.09360.2 0.0867 14-Oct R.VAAGLQIK[136.11].N "sp|Q14974|IMB1_HUMAN,tr|J3QR48|J3QR48_HUMAN" 2 806.5105 1.33 26577 9360 2 806.509658 404.2625 Importin subunit beta-1 OS=Homo sapiens OX=9606 GN=KPNB1 PE=1 SV=2 8.72 2155.3 - 4.37E+06 - - - -1.0924 - 2.045 0.213 - 311.5 1 2 0 -0.0009 8 0 0 0 4.01E+08 3.02E+08 - - - 2.7715 0.9983 221125_WJC_METTL3_EV_vs_WT_F03.09363.09363.2 0.00521 14-Jul K.DDYALGER.V "sp|Q9BV68|RN126_HUMAN,tr|K7EIY6|K7EIY6_HUMAN" 2 937.4141 2.76 26580 9363 2 937.414737 469.7143 E3 ubiquitin-protein ligase RNF126 OS=Homo sapiens OX=9606 GN=RNF126 PE=1 SV=2 4.03 2155.5 - 535805 - - - 0.6529 - 1.728 0.182 - 171.6 1 2 0 0.0006 8 0 0 0 1.29E+08 4.66E+07 - - - 2.0347 0.9997 221125_WJC_METTL3_EV_vs_WT_F03.09369.09369.2 0.000857 14-Aug R.YEEEVLSR.E sp|P07196|NFL_HUMAN 1 1023.4873 2.27 26583 9369 2 1023.486552 512.7509 Neurofilament light polypeptide OS=Homo sapiens OX=9606 GN=NEFL PE=1 SV=3 4.25 2156.2 - 6.22E+06 - - - -0.7211 - 1.645 0.4 - 234.4 1 2 0 -0.0007 8 0 0 0 3.25E+08 1.43E+08 - - - 3.4963 0.994 221125_WJC_METTL3_EV_vs_WT_F03.09370.09370.2 2 12-Jun R.LLDVDNR[166.11].V sp|P00403|COX2_HUMAN 1 853.4533 1.18 26584 9370 2 853.45386 427.7339 Cytochrome c oxidase subunit 2 OS=Homo sapiens OX=9606 GN=MT-CO2 PE=1 SV=1 4.21 2156.2 - 1.81E+06 - - - 0.655 - 1.335 0.151 - 106.2 1 2 0 0.0006 7 0 0 0 1.17E+08 9.94E+07 - - - 1.0716 0.9949 221125_WJC_METTL3_EV_vs_WT_F03.09371.09371.2 0.47 14-Jul K.ALEYVEAK.S "sp|Q14690|RRP5_HUMAN,tr|A0A3B3IUD7|A0A3B3IUD7_HUMAN" 2 921.4807 0.98 26585 9371 2 921.480226 461.7477 Protein RRP5 homolog OS=Homo sapiens OX=9606 GN=PDCD11 PE=1 SV=3 4.53 2156.4 - 707404 - - - -0.5665 - 1.416 0.139 - 156.7 1 2 0 -0.0005 8 0 0 0 4.62E+07 4.69E+07 - - - 1.1165 0.9998 221125_WJC_METTL3_EV_vs_WT_F03.09374.09374.2 0.00047 16-Sep K.IEYVDETGR.K sp|O43290|SNUT1_HUMAN 1 1080.5088 2.42 26586 9374 2 1080.508243 541.2617 U4\U6.U5 tri-snRNP-associated protein 1 OS=Homo sapiens OX=9606 GN=SART1 PE=1 SV=1 4.14 2156.8 - 1.90E+06 - - - -0.4729 - 1.913 0.424 - 253.6 1 2 0 -0.0005 9 0 0 0 7.30E+07 3.02E+07 - - - 4.0491 0.9967 221125_WJC_METTL3_EV_vs_WT_F03.09375.09375.2 0.143 14-Sep R.AGVYNLTK.S sp|Q9BY49|PECR_HUMAN 1 864.4705 1.14 26587 9375 2 864.468796 433.2425 Peroxisomal trans-2-enoyl-CoA reductase OS=Homo sapiens OX=9606 GN=PECR PE=1 SV=2 8.63 2156.9 - 1.31E+06 - - - -1.992 - 1.646 0.197 - 256.8 1 2 0 -0.0017 8 0 0 0 2.48E+08 2.18E+08 - - - 1.9985 0.9981 221125_WJC_METTL3_EV_vs_WT_F03.09376.09376.2 0.0305 14-Aug R.FIMESGAK.G "sp|P23396|RS3_HUMAN,tr|H0YEU2|H0YEU2_HUMAN,tr|E9PL09|E9PL09_HUMAN" 3 881.4317 0.54 26588 9376 2 881.430931 441.7231 40S ribosomal protein S3 OS=Homo sapiens OX=9606 GN=RPS3 PE=1 SV=2 6 2157 - 970523 - - - -0.86 - 1.449 0.241 - 202.6 1 2 0 -0.0008 8 0 0 0 8.70E+07 1.61E+08 - - - 1.9393 0.9998 221125_WJC_METTL3_EV_vs_WT_F03.09382.09382.2 5.04E-05 16-Nov K.IEYVDETGR[166.11].K sp|O43290|SNUT1_HUMAN 1 1090.517 3.19 26590 9382 2 1090.518941 546.2658 U4\U6.U5 tri-snRNP-associated protein 1 OS=Homo sapiens OX=9606 GN=SART1 PE=1 SV=1 4.14 2157.8 - 605194 - - - 1.7579 - 2.031 0.504 - 381 1 2 0 0.0019 9 0 0 0 7.09E+07 2.23E+07 - - - 4.8128 0.9997 221125_WJC_METTL3_EV_vs_WT_F03.09385.09385.2 0.00072 14-Jul R.DC[160.03]LINAAK.T "sp|P17987|TCPA_HUMAN,tr|F5H136|F5H136_HUMAN,tr|F5H7Y1|F5H7Y1_HUMAN,tr|E7ERF2|E7ERF2_HUMAN" 4 903.4484 0.47 26591 9385 2 903.447761 452.7315 T-complex protein 1 subunit alpha OS=Homo sapiens OX=9606 GN=TCP1 PE=1 SV=1 5.83 2158.2 - 1.42E+07 - - - -0.7095 - 1.63 0.419 - 231 1 2 0 -0.0006 8 0 0 0 7.66E+08 1.63E+09 - - - 3.6091 0.9995 221125_WJC_METTL3_EV_vs_WT_F03.09386.09386.2 0.000152 14-Jul K.DDYALGER[166.11].V "sp|Q9BV68|RN126_HUMAN,tr|K7EIY6|K7EIY6_HUMAN" 2 947.4224 2.63 26592 9386 2 947.420415 474.7185 E3 ubiquitin-protein ligase RNF126 OS=Homo sapiens OX=9606 GN=RNF126 PE=1 SV=2 4.03 2158.2 - 1.50E+06 - - - -2.0899 - 1.495 0.505 - 177.5 1 2 0 -0.002 8 0 0 0 1.23E+08 4.66E+07 - - - 3.9831 0.9966 221125_WJC_METTL3_EV_vs_WT_F03.09390.09390.2 3.71 12-Jul R.LLDVDNR.V sp|P00403|COX2_HUMAN 1 843.445 1.05 26594 9390 2 843.444103 422.7298 Cytochrome c oxidase subunit 2 OS=Homo sapiens OX=9606 GN=MT-CO2 PE=1 SV=1 4.21 2158.8 - 3.93E+06 - - - -1.1002 - 1.337 0.214 - 163.1 1 2 0 -0.0009 7 0 0 0 1.03E+08 9.80E+07 - - - 1.5416 0.9996 221125_WJC_METTL3_EV_vs_WT_F03.09392.09392.2 0.000395 18-Nov R.QLSSGVSEIR[166.11].H "sp|P04792|HSPB1_HUMAN,tr|A0A6Q8PGY2|A0A6Q8PGY2_HUMAN,tr|A0A6Q8PHJ6|A0A6Q8PHJ6_HUMAN,tr|A0A6Q8PHA6|A0A6Q8PHA6_HUMAN,tr|A0A6Q8PF43|A0A6Q8PF43_HUMAN,tr|A0A6Q8PFK8|A0A6Q8PFK8_HUMAN,tr|A0A6Q8PGK1|A0A6Q8PGK1_HUMAN,tr|A0A6Q8PH65|A0A6Q8PH65_HUMAN,tr|A0A6Q8PFE7|A0A6Q8PFE7_HUMAN" 9 1084.5752 2.05 26596 9392 2 1084.573392 543.2949 Heat shock protein beta-1 OS=Homo sapiens OX=9606 GN=HSPB1 PE=1 SV=2 6 2159 - 1.46E+06 - - - -1.6735 - 2.19 0.365 - 636.9 1 2 0 -0.0018 10 0 0 0 4.52E+08 2.21E+08 - - - 3.9244 0.9998 221125_WJC_METTL3_EV_vs_WT_F03.09395.09395.2 0.126 18-Sep K.EGDLIAAQAR.L "sp|P02545|LMNA_HUMAN,tr|A0A6Q8PF80|A0A6Q8PF80_HUMAN,tr|A0A804HL68|A0A804HL68_HUMAN,tr|Q5TCI8|Q5TCI8_HUMAN,tr|A0A6Q8PFJ0|A0A6Q8PFJ0_HUMAN,tr|A0A6Q8PHQ9|A0A6Q8PHQ9_HUMAN,tr|A0A6Q8PGH0|A0A6Q8PGH0_HUMAN,tr|Q3BDU5|Q3BDU5_HUMAN" 8 1042.5407 3.41 26597 9395 2 1042.540418 522.2776 Prelamin-A\C OS=Homo sapiens OX=9606 GN=LMNA PE=1 SV=1 4.37 2159.4 - 3.69E+06 - - - -0.2926 - 2.059 0.371 - 307.4 1 2 0 -0.0003 10 0 0 0 2.20E+08 6.46E+07 - - - 3.797 0.9999 221125_WJC_METTL3_EV_vs_WT_F03.09399.09399.2 8.02E-05 16-Oct K.FESPEVAER.A "sp|P52272|HNRPM_HUMAN,tr|A0A087X0X3|A0A087X0X3_HUMAN" 2 1062.4982 1.75 26599 9399 2 1062.497633 532.2564 Heterogeneous nuclear ribonucleoprotein M OS=Homo sapiens OX=9606 GN=HNRNPM PE=1 SV=3 4.25 2159.8 - 1.33E+07 - - - -0.5233 - 1.98 0.533 - 419.2 1 2 0 -0.0006 9 0 0 0 4.69E+09 2.68E+09 - - - 4.9538 0.9905 221125_WJC_METTL3_EV_vs_WT_F03.09401.09401.2 0.602 14-Jun K.ALEYVEAK[136.11].S "sp|Q14690|RRP5_HUMAN,tr|A0A3B3IUD7|A0A3B3IUD7_HUMAN" 2 929.4949 1.03 26600 9401 2 929.496869 465.7548 Protein RRP5 homolog OS=Homo sapiens OX=9606 GN=PDCD11 PE=1 SV=3 4.53 2160 - 1.60E+06 - - - 2.0667 - 1.309 0.192 - 97.8 1 2 0 0.0019 8 0 0 0 4.56E+07 4.44E+07 - - - 1.2706 0.9994 221125_WJC_METTL3_EV_vs_WT_F03.09407.09407.2 0.00682 18-Nov R.ASAVSELSPR.E "sp|Q9Y2W1|TR150_HUMAN,tr|A0A3B3ITZ9|A0A3B3ITZ9_HUMAN" 2 1015.5298 2.9 26603 9407 2 1015.528625 508.7722 Thyroid hormone receptor-associated protein 3 OS=Homo sapiens OX=9606 GN=THRAP3 PE=1 SV=2 6.05 2160.8 - 2.96E+07 - - - -1.1807 - 2.312 0.226 - 513.8 1 2 0 -0.0012 10 0 0 0 3.55E+09 1.23E+09 - - - 3.0493 0.9993 221125_WJC_METTL3_EV_vs_WT_F03.09409.09409.2 0.000515 16-Jul R.FEPYANPTK[136.11].R "sp|P52272|HNRPM_HUMAN,tr|M0R019|M0R019_HUMAN,tr|M0R0Y6|M0R0Y6_HUMAN,tr|M0R0N3|M0R0N3_HUMAN,tr|A0A087X0X3|A0A087X0X3_HUMAN,tr|M0QYQ7|M0QYQ7_HUMAN,tr|M0R2T0|M0R2T0_HUMAN" 7 1073.5273 2.32 26605 9409 2 1073.529531 537.7709 Heterogeneous nuclear ribonucleoprotein M OS=Homo sapiens OX=9606 GN=HNRNPM PE=1 SV=3 6 2160.9 - 8.19E+06 - - - 2.0679 - 1.446 0.465 - 139.7 1 2 0 0.0022 9 0 0 0 1.66E+09 7.17E+08 - - - 3.5418 0.9987 221125_WJC_METTL3_EV_vs_WT_F03.09412.09412.2 0.0116 18-Sep R.ITELTDENVK[136.11].F "sp|P19387|RPB3_HUMAN,tr|H3BRR2|H3BRR2_HUMAN" 2 1168.6067 1.38 26606 9412 2 1168.604712 585.3106 DNA-directed RNA polymerase II subunit RPB3 OS=Homo sapiens OX=9606 GN=POLR2C PE=1 SV=2 4.14 2161.2 - 197114 - - - -1.6875 - 1.689 0.287 - 209.3 1 2 0 -0.002 10 0 0 0 3.86E+07 2.81E+07 - - - 2.6232 0.9984 221125_WJC_METTL3_EV_vs_WT_F03.09414.09414.2 0.0896 12-Jun K.YSLVEAK.R sp|P15924|DESP_HUMAN 1 808.4331 5.92 26607 9414 2 808.433053 405.2238 Desmoplakin OS=Homo sapiens OX=9606 GN=DSP PE=1 SV=3 6 2161.5 - 6.73E+06 - - - -0.021 - 1.28 0.291 - 99.1 1 2 0 0 7 0 0 0 2.28E+08 3.86E+07 - - - 1.9725 0.9999 221125_WJC_METTL3_EV_vs_WT_F03.09416.09416.2 0.00115 22-Oct R.VVSGAANVIGPK.L "sp|P98173|FAM3A_HUMAN,tr|A6QRH7|A6QRH7_HUMAN,tr|Q5HY75|Q5HY75_HUMAN,tr|D3DWX8|D3DWX8_HUMAN" 4 1110.6397 1.28 26609 9416 2 1110.640114 556.3271 Protein FAM3A OS=Homo sapiens OX=9606 GN=FAM3A PE=1 SV=2 8.72 2161.6 - 2.78E+06 - - - 0.3656 - 2.129 0.539 - 241.4 1 2 0 0.0004 12 0 0 0 1.57E+08 1.22E+08 - - - 5.0102 0.9948 221125_WJC_METTL3_EV_vs_WT_F03.09419.09419.2 0.508 12-Jul K.VFESIGK.F "sp|P35232|PHB_HUMAN,tr|C9JZ20|C9JZ20_HUMAN,tr|E7ESE2|E7ESE2_HUMAN,tr|E9PCW0|E9PCW0_HUMAN,tr|C9JW96|C9JW96_HUMAN" 5 778.4225 0.82 26610 9419 2 778.422241 390.2185 Prohibitin OS=Homo sapiens OX=9606 GN=PHB PE=1 SV=1 5.97 2161.9 - 2.16E+06 - - - -0.3391 - 1.353 0.145 - 159.3 1 2 0 -0.0003 7 0 0 0 1.22E+08 1.49E+08 - - - 1.0698 0.9786 221125_WJC_METTL3_EV_vs_WT_F03.09420.09420.2 2.19 16-May K.NISGSVTLK.L "sp|Q9NZW5|PALS2_HUMAN,tr|C9J4Q3|C9J4Q3_HUMAN,tr|B8ZZG1|B8ZZG1_HUMAN,tr|C9JGI8|C9JGI8_HUMAN" 4 917.5182 0.28 26611 9420 2 917.518279 459.7664 Protein PALS2 OS=Homo sapiens OX=9606 GN=PALS2 PE=1 SV=2 8.75 2162 - 1.28E+06 - - - 0.0905 - 1.129 0.149 - 65.9 7 2 0 0.0001 9 0 0 0 5.67E+07 2.05E+08 - - - 0.115 0.9992 221125_WJC_METTL3_EV_vs_WT_F03.09428.09428.2 0.0111 12-Jul R.TYTQLVR.L "sp|O75643|U520_HUMAN,tr|A0A494C1A5|A0A494C1A5_HUMAN" 2 879.4814 1.96 26616 9428 2 879.480786 440.748 U5 small nuclear ribonucleoprotein 200 kDa helicase OS=Homo sapiens OX=9606 GN=SNRNP200 PE=1 SV=2 8.41 2162.9 - 6.84E+06 - - - -0.7175 - 1.484 0.323 - 205.6 1 2 0 -0.0006 7 0 0 0 4.32E+08 2.20E+08 - - - 2.6772 0.9999 221125_WJC_METTL3_EV_vs_WT_F03.09436.09436.2 4.14E-06 13/22 R.VVSGAANVIGPK[136.11].L "sp|P98173|FAM3A_HUMAN,tr|A6QRH7|A6QRH7_HUMAN,tr|Q5HY75|Q5HY75_HUMAN,tr|D3DWX8|D3DWX8_HUMAN" 4 1118.6539 1.28 26622 9436 2 1118.653099 560.3342 Protein FAM3A OS=Homo sapiens OX=9606 GN=FAM3A PE=1 SV=2 8.72 2163.6 - 3.67E+06 - - - -0.7232 - 2.513 0.551 - 439.9 1 2 0 -0.0008 12 0 0 0 1.57E+08 1.22E+08 - - - 5.535 0.9979 221125_WJC_METTL3_EV_vs_WT_F03.09437.09437.2 0.0888 14-Jun R.AVVIVDDR[166.11].G "sp|P23246|SFPQ_HUMAN,sp|Q15233|NONO_HUMAN,tr|A0A7I2V535|A0A7I2V535_HUMAN,tr|A0A7I2V4N2|A0A7I2V4N2_HUMAN,tr|A0A7I2V464|A0A7I2V464_HUMAN,tr|A0A7P0MRW0|A0A7P0MRW0_HUMAN,tr|H7C367|H7C367_HUMAN,tr|C9IZL7|C9IZL7_HUMAN,tr|A0A7I2V4J2|A0A7I2V4J2_HUMAN,tr|A0A7I2V5Y7|A0A7I2V5Y7_HUMAN" 10 895.5003 0.98 26623 9437 2 895.500034 448.7574 "Splicing factor, proline- and glutamine-rich OS=Homo sapiens OX=9606 GN=SFPQ PE=1 SV=2" 4.21 2163.7 - 2.59E+06 - - - -0.2434 - 1.481 0.207 - 189.3 1 2 0 -0.0002 8 0 0 0 2.36E+08 2.42E+08 - - - 1.7543 0.9996 221125_WJC_METTL3_EV_vs_WT_F03.09439.09439.2 0.00269 16-Jul K.LTPVAYGC[160.03]R.V "sp|Q16875|F263_HUMAN,tr|A0A1W2PR17|A0A1W2PR17_HUMAN,tr|Q5W015|Q5W015_HUMAN,tr|F2Z2I2|F2Z2I2_HUMAN,tr|H0Y483|H0Y483_HUMAN,tr|Q5VX20|Q5VX20_HUMAN" 6 1035.5172 0.58 26624 9439 2 1035.516664 518.7659 "6-phosphofructo-2-kinase\fructose-2,6-bisphosphatase 3 OS=Homo sapiens OX=9606 GN=PFKFB3 PE=1 SV=1" 8.22 2163.9 - 3.13E+06 - - - -0.4703 - 1.622 0.399 - 137.1 1 2 0 -0.0005 9 0 0 0 1.70E+08 2.94E+08 - - - 3.3871 0.9997 221125_WJC_METTL3_EV_vs_WT_F03.09441.09441.2 0.000209 14-Aug R.DC[160.03]LINAAK[136.11].T "sp|P17987|TCPA_HUMAN,tr|F5H136|F5H136_HUMAN,tr|F5H7Y1|F5H7Y1_HUMAN,tr|E7ERF2|E7ERF2_HUMAN" 4 911.4626 0.46 26625 9441 2 911.461959 456.7386 T-complex protein 1 subunit alpha OS=Homo sapiens OX=9606 GN=TCP1 PE=1 SV=1 5.83 2164.1 - 2.43E+07 - - - -0.7055 - 1.619 0.459 - 289.2 1 2 0 -0.0006 8 0 0 0 7.55E+08 1.62E+09 - - - 3.8841 0.9945 221125_WJC_METTL3_EV_vs_WT_F03.09442.09442.2 0.575 14-Jul K.ELEIAQDR.N sp|P12270|TPR_HUMAN 1 972.4876 2.54 26626 9442 2 972.487844 487.2511 Nucleoprotein TPR OS=Homo sapiens OX=9606 GN=TPR PE=1 SV=3 4.14 2164.1 - 3.32E+06 - - - 0.2262 - 1.301 0.165 - 232.9 1 2 0 0.0002 8 0 0 0 1.09E+08 4.28E+07 - - - 1.0532 0.9962 221125_WJC_METTL3_EV_vs_WT_F03.09443.09443.2 0.0557 14-Jun K.WQEPPPVK.Q "sp|Q8WWY3|PRP31_HUMAN,tr|E7EVX8|E7EVX8_HUMAN" 2 979.5127 1.42 26627 9443 2 979.512309 490.7636 U4\U6 small nuclear ribonucleoprotein Prp31 OS=Homo sapiens OX=9606 GN=PRPF31 PE=1 SV=2 6 2164.2 - 3.07E+06 - - - -0.4165 - 1.079 0.277 - 152.5 1 2 0 -0.0004 8 0 0 0 2.25E+08 1.58E+08 - - - 1.3161 0.9997 221125_WJC_METTL3_EV_vs_WT_F03.09449.09449.2 0.0265 14-Sep K.NQELEVVR.Q "sp|Q14203|DCTN1_HUMAN,tr|A0A804CDA6|A0A804CDA6_HUMAN,tr|E7EX90|E7EX90_HUMAN,tr|A0A7P0Z4C3|A0A7P0Z4C3_HUMAN,tr|Q6AWB1|Q6AWB1_HUMAN" 5 985.5193 2.48 26630 9449 2 985.518642 493.7669 Dynactin subunit 1 OS=Homo sapiens OX=9606 GN=DCTN1 PE=1 SV=3 4.53 2164.9 - 1.35E+07 - - - -0.6261 - 1.937 0.358 - 581.2 1 2 0 -0.0006 8 0 0 0 5.08E+08 2.05E+08 - - - 3.679 0.9657 221125_WJC_METTL3_EV_vs_WT_F03.09450.09450.2 1.96 14-May K.LFSSQYGK[136.11].M "sp|P49792|RBP2_HUMAN,sp|A6NKT7|RGPD3_HUMAN,tr|J3KNE0|J3KNE0_HUMAN" 3 936.4796 1.32 26631 9450 2 936.478328 469.2471 E3 SUMO-protein ligase RanBP2 OS=Homo sapiens OX=9606 GN=RANBP2 PE=1 SV=2 8.59 2164.9 - 2.30E+06 - - - -1.3924 - 1 0.136 - 59.4 1 2 0 -0.0013 8 0 0 0 1.05E+08 7.94E+07 - - - 0.0451 0.9943 221125_WJC_METTL3_EV_vs_WT_F03.09453.09453.2 0.878 12-Jul K.SEITELR.R "sp|P13645|K1C10_HUMAN,sp|Q8TDM6|DLG5_HUMAN,tr|A0A1B0GVI3|A0A1B0GVI3_HUMAN" 3 846.4447 1177.47 26632 9453 2 846.444181 424.2296 "Keratin, type I cytoskeletal 10 OS=Homo sapiens OX=9606 GN=KRT10 PE=1 SV=6" 4.53 2165.3 - 2.47E+06 - - - -0.6096 - 1.468 0.106 - 263.6 1 2 0 -0.0005 7 0 0 0 1.14E+10 9.70E+06 - - - 1.0402 0.9997 221125_WJC_METTL3_EV_vs_WT_F03.09457.09457.2 0.000878 14-Sep K.NQELEVVR[166.11].Q "sp|Q14203|DCTN1_HUMAN,tr|A0A804CDA6|A0A804CDA6_HUMAN,tr|E7EX90|E7EX90_HUMAN,tr|A0A7P0Z4C3|A0A7P0Z4C3_HUMAN,tr|Q6AWB1|Q6AWB1_HUMAN" 5 995.5275 2.46 26634 9457 2 995.527286 498.771 Dynactin subunit 1 OS=Homo sapiens OX=9606 GN=DCTN1 PE=1 SV=3 4.53 2165.8 - 6.66E+06 - - - -0.2441 - 1.948 0.338 - 598.3 1 2 0 -0.0002 8 0 0 0 5.04E+08 2.05E+08 - - - 3.5484 0.9043 221125_WJC_METTL3_EV_vs_WT_F03.09458.09458.2 0.00987 16-Jul K.IENESDMIR.N sp|O00186|STXB3_HUMAN 1 1105.5074 0.09 26635 9458 2 1105.517345 553.761 Syntaxin-binding protein 3 OS=Homo sapiens OX=9606 GN=STXBP3 PE=1 SV=2 4.14 2165.9 - 446705 - - - 9.0194 - 1.347 0.359 - 87.5 1 2 0 0.01 9 0 0 0 1.01E+07 1.07E+08 - - - 2.5512 0.9424 221125_WJC_METTL3_EV_vs_WT_F03.09461.09461.2 3.39 12-May K.AFSQFGK[136.11].L "sp|O60506|HNRPQ_HUMAN,tr|A0A7I2YQV8|A0A7I2YQV8_HUMAN,tr|A0A7I2YQN2|A0A7I2YQN2_HUMAN,tr|A0A7I2V4Z0|A0A7I2V4Z0_HUMAN,tr|B7Z645|B7Z645_HUMAN,tr|A0A7I2V2F2|A0A7I2V2F2_HUMAN,tr|A0A7I2V346|A0A7I2V346_HUMAN,tr|A0A7I2V309|A0A7I2V309_HUMAN" 8 791.4057 1.09 26636 9461 2 791.405836 396.7101 Heterogeneous nuclear ribonucleoprotein Q OS=Homo sapiens OX=9606 GN=SYNCRIP PE=1 SV=2 8.8 2166.3 - 3.53E+06 - - - 0.1226 - 0.849 0.129 - 83.4 1 2 0 0.0001 7 0 0 0 3.24E+08 2.96E+08 - - - -0.5249 0.9721 221125_WJC_METTL3_EV_vs_WT_F03.09465.09465.2 0.237 16-Aug K.ISGNPSLIK.N "sp|Q9H334|FOXP1_HUMAN,tr|A0A3B3IRW5|A0A3B3IRW5_HUMAN,tr|A0A3B3IRS5|A0A3B3IRS5_HUMAN,tr|A0A3B3IST0|A0A3B3IST0_HUMAN,tr|A0A3B3IUB6|A0A3B3IUB6_HUMAN,tr|H0Y882|H0Y882_HUMAN,tr|A0A3B3IT66|A0A3B3IT66_HUMAN,tr|A0A3B3IS87|A0A3B3IS87_HUMAN,tr|A0A0B4J2F3|A0A0B4J2F3_HUMAN,tr|A0A3B3IST6|A0A3B3IST6_HUMAN" 10 927.5389 2.51 26638 9465 2 927.541863 464.7767 Forkhead box protein P1 OS=Homo sapiens OX=9606 GN=FOXP1 PE=1 SV=1 8.75 2166.8 - 2.68E+06 - - - 3.16 - 1.374 0.145 - 89.9 1 2 0 0.0029 9 0 0 0 2.61E+08 1.04E+08 - - - 1.0302 0.9904 221125_WJC_METTL3_EV_vs_WT_F03.09466.09466.2 0.171 12-Jun K.AFSQFGK.L "sp|O60506|HNRPQ_HUMAN,tr|A0A7I2YQV8|A0A7I2YQV8_HUMAN,tr|A0A7I2YQN2|A0A7I2YQN2_HUMAN,tr|A0A7I2V4Z0|A0A7I2V4Z0_HUMAN,tr|B7Z645|B7Z645_HUMAN,tr|A0A7I2V2F2|A0A7I2V2F2_HUMAN,tr|A0A7I2V346|A0A7I2V346_HUMAN,tr|A0A7I2V309|A0A7I2V309_HUMAN" 8 783.3915 1.08 26639 9466 2 783.391032 392.703 Heterogeneous nuclear ribonucleoprotein Q OS=Homo sapiens OX=9606 GN=SYNCRIP PE=1 SV=2 8.8 2166.9 - 2.87E+06 - - - -0.6472 - 1.078 0.191 - 133 1 2 0 -0.0005 7 0 0 0 3.18E+08 2.95E+08 - - - 0.6895 0.9977 221125_WJC_METTL3_EV_vs_WT_F03.09470.09470.2 0.0498 16-May R.VPPPPPIAR[166.11].A "sp|P07910|HNRPC_HUMAN,tr|B4DY08|B4DY08_HUMAN,tr|G3V575|G3V575_HUMAN,tr|G3V5V7|G3V5V7_HUMAN,tr|B2R5W2|B2R5W2_HUMAN,tr|G3V4C1|G3V4C1_HUMAN,tr|G3V576|G3V576_HUMAN,tr|G3V2D6|G3V2D6_HUMAN,tr|G3V4W0|G3V4W0_HUMAN,tr|G3V555|G3V555_HUMAN,tr|G3V2Q1|G3V2Q1_HUMAN" 11 952.5734 1.29 26642 9470 2 952.572399 477.294 Heterogeneous nuclear ribonucleoproteins C1\C2 OS=Homo sapiens OX=9606 GN=HNRNPC PE=1 SV=4 9.72 2167.3 - 2.12E+07 - - - -1.0057 - 1.195 0.305 - 95.1 1 2 0 -0.001 9 0 0 0 1.08E+09 8.39E+08 - - - 1.8088 0.9949 221125_WJC_METTL3_EV_vs_WT_F03.09476.09476.2 0.00361 18-Jul K.VIAQLSEC[160.03]EK.H "sp|Q92878|RAD50_HUMAN,tr|A0A1W2PQ90|A0A1W2PQ90_HUMAN" 2 1175.5856 0.57 26645 9476 2 1175.590207 588.8001 DNA repair protein RAD50 OS=Homo sapiens OX=9606 GN=RAD50 PE=1 SV=1 4.53 2168 - 270934 - - - 3.8985 - 1.237 0.439 - 106.4 1 2 0 0.0046 10 0 0 0 5.45E+06 9.49E+06 - - - 2.8757 0.9998 221125_WJC_METTL3_EV_vs_WT_F03.09477.09477.2 0.00371 18-Oct R.ITELTDENVK.F "sp|P19387|RPB3_HUMAN,tr|H3BRR2|H3BRR2_HUMAN" 2 1160.5925 1.38 26646 9477 2 1160.59177 581.3035 DNA-directed RNA polymerase II subunit RPB3 OS=Homo sapiens OX=9606 GN=POLR2C PE=1 SV=2 4.14 2168.1 - 1.04E+06 - - - -0.6152 - 2.024 0.403 - 272 1 2 0 -0.0007 10 0 0 0 3.86E+07 2.81E+07 - - - 3.9854 0.9999 221125_WJC_METTL3_EV_vs_WT_F03.09480.09480.2 0.000121 16-Aug K.YGTFVNEEK[136.11].M "sp|O60934|NBN_HUMAN,tr|E5RGU1|E5RGU1_HUMAN" 2 1093.5171 1.16 26647 9480 2 1093.51682 547.7658 Nibrin OS=Homo sapiens OX=9606 GN=NBN PE=1 SV=1 4.53 2168.5 - 683488 - - - -0.2926 - 1.742 0.538 - 163 1 2 0 -0.0003 9 0 0 0 2.12E+07 1.82E+07 - - - 4.6203 0.9983 221125_WJC_METTL3_EV_vs_WT_F03.09482.09482.2 0.179 12-Jun R.FSGVPDR.F "sp|A0A075B6R9|KVD24_HUMAN,sp|A0A0C4DH68|KV224_HUMAN,sp|A2NJV5|KV229_HUMAN,sp|A0A075B6S2|KVD29_HUMAN,sp|A0A0A0MRZ7|KVD26_HUMAN" 5 776.3817 30.44 26648 9482 2 776.38145 389.1981 Probable non-functional immunoglobulin kappa variable 2D-24 OS=Homo sapiens OX=9606 GN=IGKV2D-24 PE=1 SV=1 5.84 2168.7 - 1.91E+06 - - - -0.3259 - 1.364 0.257 - 108.8 1 2 0 -0.0003 7 0 0 0 1.67E+08 5.47E+06 - - - 1.9227 0.8912 221125_WJC_METTL3_EV_vs_WT_F03.09484.09484.2 3.9 12-Jul R.IVEDWQK.L sp|P42345|MTOR_HUMAN 1 916.4654 1.11 26649 9484 2 916.46341 459.24 Serine\threonine-protein kinase mTOR OS=Homo sapiens OX=9606 GN=MTOR PE=1 SV=1 4.37 2168.9 - 976346 - - - -2.2063 - 1.007 0.074 - 102.7 1 2 0 -0.002 7 0 0 0 2.17E+07 1.96E+07 - - - -0.391 0.9822 221125_WJC_METTL3_EV_vs_WT_F03.09486.09486.2 0.172 16-Sep R.QLGLEGAAR.A sp|Q8N5C6|SRBD1_HUMAN 1 913.4981 0.51 26650 9486 2 913.496962 457.7563 S1 RNA-binding domain-containing protein 1 OS=Homo sapiens OX=9606 GN=SRBD1 PE=1 SV=2 6 2169.2 - 1.79E+06 - - - -1.2786 - 1.468 0.039 - 181 1 2 0 -0.0012 9 0 0 0 3.39E+07 6.63E+07 - - - 0.4393 0.9897 221125_WJC_METTL3_EV_vs_WT_F03.09488.09488.2 0.104 16-Sep R.SLMSADNVR[166.11].Q sp|O43143|DHX15_HUMAN 1 1001.484 1 26652 9488 2 1001.488209 501.7493 Pre-mRNA-splicing factor ATP-dependent RNA helicase DHX15 OS=Homo sapiens OX=9606 GN=DHX15 PE=1 SV=2 5.55 2169.4 - 945472 - - - 4.2527 - 1.576 0.285 - 237.1 1 2 0 0.0043 9 0 0 0 1.57E+08 1.57E+08 - - - 2.4607 0.9999 221125_WJC_METTL3_EV_vs_WT_F03.09489.09489.2 0.00887 18-Oct R.LIEDNEYTAR.Q "sp|P07947|YES_HUMAN,sp|P06239|LCK_HUMAN,sp|P06241|FYN_HUMAN,sp|P12931|SRC_HUMAN,tr|Q573B4|Q573B4_HUMAN,tr|J3QRU1|J3QRU1_HUMAN" 6 1222.583 0.72 26653 9489 2 1222.581467 612.2988 Tyrosine-protein kinase Yes OS=Homo sapiens OX=9606 GN=YES1 PE=1 SV=3 4.14 2169.5 - 450885 - - - -1.2384 - 2.055 0.55 - 336.8 1 2 0 -0.0015 10 0 0 0 2.50E+07 3.46E+07 - - - 5.1133 0.9979 221125_WJC_METTL3_EV_vs_WT_F03.09492.09492.2 0.116 16-Nov K.ISGNPSLIK[136.11].N "sp|Q9H334|FOXP1_HUMAN,tr|A0A3B3IRW5|A0A3B3IRW5_HUMAN,tr|A0A3B3IRS5|A0A3B3IRS5_HUMAN,tr|A0A3B3IST0|A0A3B3IST0_HUMAN,tr|A0A3B3IUB6|A0A3B3IUB6_HUMAN,tr|H0Y882|H0Y882_HUMAN,tr|A0A3B3IT66|A0A3B3IT66_HUMAN,tr|A0A3B3IS87|A0A3B3IS87_HUMAN,tr|A0A0B4J2F3|A0A0B4J2F3_HUMAN,tr|A0A3B3IST6|A0A3B3IST6_HUMAN" 10 935.5531 2.51 26654 9492 2 935.55173 468.7838 Forkhead box protein P1 OS=Homo sapiens OX=9606 GN=FOXP1 PE=1 SV=1 8.75 2169.9 - 3.35E+06 - - - -1.4986 - 1.786 0.189 - 203.4 1 2 0 -0.0014 9 0 0 0 2.62E+08 1.04E+08 - - - 2.1144 0.9781 221125_WJC_METTL3_EV_vs_WT_F03.09493.09493.2 0.0723 16-Aug K.VPVPLNTTK.Y sp|Q9Y6X8|ZHX2_HUMAN 1 967.5702 3.62 26655 9493 2 967.565623 484.7924 Zinc fingers and homeoboxes protein 2 OS=Homo sapiens OX=9606 GN=ZHX2 PE=1 SV=1 8.72 2169.9 - 1.70E+06 - - - -4.7635 - 1.29 0.314 - 227.2 1 2 0 -0.0046 9 0 0 0 8.20E+07 2.26E+07 - - - 2.0955 0.9989 221125_WJC_METTL3_EV_vs_WT_F03.09494.09494.2 0.00774 14-Sep K.LIEVDDER[166.11].K "sp|P62753|RS6_HUMAN,tr|A2A3R7|A2A3R7_HUMAN" 2 997.4956 1.02 26656 9494 2 997.492574 499.7551 40S ribosomal protein S6 OS=Homo sapiens OX=9606 GN=RPS6 PE=1 SV=1 3.92 2170 - 3.40E+06 - - - -2.9935 - 1.823 0.404 - 296.1 1 2 0 -0.003 8 0 0 0 1.01E+09 9.90E+08 - - - 3.835 0.9985 221125_WJC_METTL3_EV_vs_WT_F03.09499.09499.2 0.0332 16-Jul K.FDVDAADEK.F sp|Q9H0D6|XRN2_HUMAN 1 1008.44 1.47 26659 9499 2 1008.437852 505.2273 5'-3' exoribonuclease 2 OS=Homo sapiens OX=9606 GN=XRN2 PE=1 SV=1 3.84 2170.6 - 1.14E+06 - - - -2.136 - 1.525 0.346 - 135.7 1 2 0 -0.0022 9 0 0 0 2.97E+07 2.02E+07 - - - 2.8167 0.9983 221125_WJC_METTL3_EV_vs_WT_F03.09502.09502.2 0.0216 13/18 K.C[160.03]LIATGGTPR[166.11].S "sp|O95831|AIFM1_HUMAN,tr|A0A6Q8PFW2|A0A6Q8PFW2_HUMAN,tr|A0A6Q8PFA7|A0A6Q8PFA7_HUMAN,tr|A0A6Q8PHJ9|A0A6Q8PHJ9_HUMAN,tr|A0A6Q8PFS4|A0A6Q8PFS4_HUMAN,tr|A0A6Q8PFE1|A0A6Q8PFE1_HUMAN,tr|A0A7I2RLJ8|A0A7I2RLJ8_HUMAN,tr|A0A6Q8PFQ8|A0A6Q8PFQ8_HUMAN,tr|A0A6Q8PHC0|A0A6Q8PHC0_HUMAN,tr|A0A6Q8PFM5|A0A6Q8PFM5_HUMAN" 10 1054.5469 0.4 26661 9502 2 1054.543985 528.2807 "Apoptosis-inducing factor 1, mitochondrial OS=Homo sapiens OX=9606 GN=AIFM1 PE=1 SV=1" 8.25 2170.9 - 1.87E+06 - - - -2.749 - 1.962 0.295 - 545.3 1 2 0 -0.0029 10 0 0 0 2.77E+07 6.94E+07 - - - 3.1002 0.9752 221125_WJC_METTL3_EV_vs_WT_F03.09506.09506.2 0.309 12-Jul K.FGYSVNR[166.11].K "sp|Q9Y3C1|NOP16_HUMAN,tr|D6RC60|D6RC60_HUMAN,tr|A0A0C4DGU5|A0A0C4DGU5_HUMAN,tr|D6RIC3|D6RIC3_HUMAN,tr|A0A087X2G6|A0A087X2G6_HUMAN,tr|A0A087WU10|A0A087WU10_HUMAN" 6 851.4165 1.03 26664 9506 2 851.413751 426.7155 Nucleolar protein 16 OS=Homo sapiens OX=9606 GN=NOP16 PE=1 SV=2 8.75 2171.2 - 8.02E+06 - - - -3.2546 - 1.127 0.234 - 155.2 1 2 0 -0.0028 7 0 0 0 6.34E+07 6.16E+07 - - - 1.1473 0.9996 221125_WJC_METTL3_EV_vs_WT_F03.09512.09512.2 0.000196 20-Oct K.LQAAVDGPMDK[136.11].K "sp|P51572|BAP31_HUMAN,tr|A0A2R8Y5M6|A0A2R8Y5M6_HUMAN" 2 1151.5736 1.43 26667 9512 2 1151.57075 576.7941 B-cell receptor-associated protein 31 OS=Homo sapiens OX=9606 GN=BCAP31 PE=1 SV=3 4.21 2172 - 509935 - - - -2.4827 - 2.151 0.497 - 317.6 1 2 0 -0.0029 11 0 0 0 9.50E+07 6.62E+07 - - - 4.783 0.9997 221125_WJC_METTL3_EV_vs_WT_F03.09515.09515.2 0.000327 16-Sep K.DAMMAMNGK.S "sp|Q14011|CIRBP_HUMAN,tr|K7ER40|K7ER40_HUMAN,tr|K7ENX8|K7ENX8_HUMAN,tr|K7EJV1|K7EJV1_HUMAN,tr|K7EJV5|K7EJV5_HUMAN,tr|K7ELT6|K7ELT6_HUMAN,tr|K7EMY9|K7EMY9_HUMAN,tr|K7ELV6|K7ELV6_HUMAN,tr|K7EQR7|K7EQR7_HUMAN,tr|K7EPM4|K7EPM4_HUMAN,tr|D6W5Y5|D6W5Y5_HUMAN" 11 967.3925 0.96 26669 9515 2 967.390756 484.7035 Cold-inducible RNA-binding protein OS=Homo sapiens OX=9606 GN=CIRBP PE=1 SV=1 5.84 2172.3 - 3.11E+06 - - - -1.8483 - 1.846 0.471 - 327.8 1 2 0 -0.0018 9 0 0 0 1.04E+08 1.08E+08 - - - 4.2927 0.9914 221125_WJC_METTL3_EV_vs_WT_F03.09516.09516.2 1.21 16-Jul R.VPPPPPIAR.A "sp|P07910|HNRPC_HUMAN,tr|B4DY08|B4DY08_HUMAN,tr|G3V575|G3V575_HUMAN,tr|G3V5V7|G3V5V7_HUMAN,tr|B2R5W2|B2R5W2_HUMAN,tr|G3V4C1|G3V4C1_HUMAN,tr|G3V576|G3V576_HUMAN,tr|G3V2D6|G3V2D6_HUMAN,tr|G3V4W0|G3V4W0_HUMAN,tr|G3V555|G3V555_HUMAN,tr|G3V2Q1|G3V2Q1_HUMAN" 11 942.5651 1.54 26670 9516 2 942.564687 472.2898 Heterogeneous nuclear ribonucleoproteins C1\C2 OS=Homo sapiens OX=9606 GN=HNRNPC PE=1 SV=4 9.72 2172.4 - 2.44E+07 - - - -0.4244 - 1.301 0.126 - 126.3 1 2 0 -0.0004 9 0 0 0 8.29E+09 5.37E+09 - - - 0.7328 0.999 221125_WJC_METTL3_EV_vs_WT_F03.09518.09518.2 0.0157 12-Aug R.VEYLDDR[166.11].N "sp|P04637|P53_HUMAN,tr|E7ESS1|E7ESS1_HUMAN,tr|J3KP33|J3KP33_HUMAN,tr|E9PFT5|E9PFT5_HUMAN,tr|A0A087X1Q1|A0A087X1Q1_HUMAN,tr|A0A0U1RQC9|A0A0U1RQC9_HUMAN,tr|A0A087WT22|A0A087WT22_HUMAN,tr|A0A087WXZ1|A0A087WXZ1_HUMAN,tr|E7EQX7|E7EQX7_HUMAN" 9 918.4322 0.93 26672 9518 2 918.430149 460.2234 Cellular tumor antigen p53 OS=Homo sapiens OX=9606 GN=TP53 PE=1 SV=4 4.03 2172.6 - 1.21E+06 - - - -2.268 - 1.615 0.377 - 314.5 1 2 0 -0.0021 7 0 0 0 1.54E+08 1.66E+08 - - - 3.3437 0.9905 221125_WJC_METTL3_EV_vs_WT_F03.09522.09522.2 0.127 12-Jun K.VPTFDER.F sp|O43505|B4GA1_HUMAN 1 862.4185 0.85 26674 9522 2 862.415617 432.2165 "Beta-1,4-glucuronyltransferase 1 OS=Homo sapiens OX=9606 GN=B4GAT1 PE=1 SV=1" 4.37 2173 - 2.44E+06 - - - -3.3221 - 1.506 0.215 - 172.7 1 2 0 -0.0029 7 0 0 0 3.51E+08 4.13E+08 - - - 1.9255 0.9995 221125_WJC_METTL3_EV_vs_WT_F03.09523.09523.2 0.0019 20-Oct K.LQAAVDGPMDK.K "sp|P51572|BAP31_HUMAN,tr|A0A2R8Y5M6|A0A2R8Y5M6_HUMAN" 2 1143.5594 1.47 26675 9523 2 1143.556423 572.787 B-cell receptor-associated protein 31 OS=Homo sapiens OX=9606 GN=BCAP31 PE=1 SV=3 4.21 2173.2 - 862611 - - - -2.6111 - 2.27 0.433 - 311 1 2 0 -0.003 11 0 0 0 9.72E+07 6.61E+07 - - - 4.4559 0.9993 221125_WJC_METTL3_EV_vs_WT_F03.09530.09530.2 0.162 16-Sep R.LLQQEEEIK[136.11].S "sp|P54136|SYRC_HUMAN,tr|E5RJM9|E5RJM9_HUMAN,tr|E5RH09|E5RH09_HUMAN" 3 1136.6169 0.96 26680 9530 2 1136.615784 569.3157 "Arginine--tRNA ligase, cytoplasmic OS=Homo sapiens OX=9606 GN=RARS1 PE=1 SV=2" 4.25 2173.9 - 1.50E+06 - - - -0.9414 - 2.017 0.243 - 227 1 2 0 -0.0011 9 0 0 0 2.57E+08 2.69E+08 - - - 2.8653 0.9996 221125_WJC_METTL3_EV_vs_WT_F03.09533.09533.2 0.0019 16-Sep K.AELDDTPMR.G sp|P23246|SFPQ_HUMAN 1 1046.4703 0.97 26681 9533 2 1046.469392 524.2424 "Splicing factor, proline- and glutamine-rich OS=Homo sapiens OX=9606 GN=SFPQ PE=1 SV=2" 4.03 2174.3 - 2.48E+06 - - - -0.8295 - 1.694 0.389 - 179.5 1 2 0 -0.0009 9 0 0 0 3.28E+08 3.36E+08 - - - 3.4388 1 221125_WJC_METTL3_EV_vs_WT_F03.09534.09534.2 2.42E-06 22-Dec K.VVTDTDETELAR[166.11].Q sp|P05198|IF2A_HUMAN 1 1357.6601 1.04 26682 9534 2 1357.657555 679.8373 Eukaryotic translation initiation factor 2 subunit 1 OS=Homo sapiens OX=9606 GN=EIF2S1 PE=1 SV=3 3.92 2174.4 - 954743 - - - -1.8443 - 2.616 0.605 - 410.8 1 2 0 -0.0025 12 0 0 0 2.28E+08 2.18E+08 - - - 6.039 0.9962 221125_WJC_METTL3_EV_vs_WT_F03.09538.09538.2 0.125 12-Jun K.VPTFDER[166.11].F sp|O43505|B4GA1_HUMAN 1 872.4268 0.85 26684 9538 2 872.425898 437.2207 "Beta-1,4-glucuronyltransferase 1 OS=Homo sapiens OX=9606 GN=B4GAT1 PE=1 SV=1" 4.37 2175 - 4.46E+06 - - - -0.9789 - 1.194 0.246 - 168 1 2 0 -0.0009 7 0 0 0 3.51E+08 4.15E+08 - - - 1.4195 0.9992 221125_WJC_METTL3_EV_vs_WT_F03.09540.09540.2 0.175 14-Sep R.FMSAYEQR[166.11].L sp|Q15428|SF3A2_HUMAN 1 1040.4625 0.65 26686 9540 2 1040.459953 521.2385 Splicing factor 3A subunit 2 OS=Homo sapiens OX=9606 GN=SF3A2 PE=1 SV=2 6 2175.1 - 2.09E+06 - - - -2.4345 - 1.784 0.395 - 301.9 1 2 0 -0.0025 8 0 0 0 4.14E+07 6.41E+07 - - - 3.7035 0.9998 221125_WJC_METTL3_EV_vs_WT_F03.09541.09541.2 2.26E-08 22-Oct K.VVTDTDETELAR.Q sp|P05198|IF2A_HUMAN 1 1347.6518 1.04 26687 9541 2 1347.650001 674.8332 Eukaryotic translation initiation factor 2 subunit 1 OS=Homo sapiens OX=9606 GN=EIF2S1 PE=1 SV=3 3.92 2175.3 - 1.39E+06 - - - -1.3268 - 2.091 0.472 - 292.7 1 2 0 -0.0018 12 0 0 0 2.28E+08 2.18E+08 - - - 4.4675 0.9964 221125_WJC_METTL3_EV_vs_WT_F03.09542.09542.2 0.0474 12-May K.DNNLLGR[166.11].F "sp|P0DMV8|HS71A_HUMAN,sp|P34931|HS71L_HUMAN,sp|P0DMV9|HS71B_HUMAN,sp|P17066|HSP76_HUMAN,tr|Q53FA3|Q53FA3_HUMAN,tr|V9GZ37|V9GZ37_HUMAN,tr|A0A0G2JIW1|A0A0G2JIW1_HUMAN" 7 810.4223 0.14 26688 9542 2 810.421098 406.2184 Heat shock 70 kDa protein 1A OS=Homo sapiens OX=9606 GN=HSPA1A PE=1 SV=1 5.84 2175.4 - 1.33E+06 - - - -1.5276 - 1.241 0.267 - 142.1 1 2 0 -0.0012 7 0 0 0 2.96E+09 2.16E+10 - - - 1.6968 0.7811 221125_WJC_METTL3_EV_vs_WT_F03.09544.09544.2 0.178 12-Jun S.SDDMLIK.L "sp|P35606|COPB2_HUMAN,tr|H0Y938|H0Y938_HUMAN,tr|A0A7I2V3G0|A0A7I2V3G0_HUMAN,tr|A0A7I2V258|A0A7I2V258_HUMAN,tr|D6RBT6|D6RBT6_HUMAN,tr|H0YAC7|H0YAC7_HUMAN,tr|A0A7I2YQF9|A0A7I2YQF9_HUMAN" 7 820.4001 1.32 26689 9544 2 820.399129 411.2073 Coatomer subunit beta' OS=Homo sapiens OX=9606 GN=COPB2 PE=1 SV=2 4.21 2175.6 - 9.71E+06 - - - -1.1287 - 1.35 0.181 - 237.8 1 1 0 -0.0009 7 0 0 0 7.87E+09 5.96E+09 - - - 1.3285 0.9998 221125_WJC_METTL3_EV_vs_WT_F03.09546.09546.2 0.0338 14-Sep K.LIEVDDER.K "sp|P62753|RS6_HUMAN,tr|A2A3R7|A2A3R7_HUMAN" 2 987.4873 1.03 26690 9546 2 987.486323 494.7509 40S ribosomal protein S6 OS=Homo sapiens OX=9606 GN=RPS6 PE=1 SV=1 3.92 2175.8 - 3.11E+07 - - - -0.9793 - 1.964 0.402 - 313.9 1 2 0 -0.001 8 0 0 0 1.00E+09 9.80E+08 - - - 4.0456 0.9998 221125_WJC_METTL3_EV_vs_WT_F03.09547.09547.2 5.15E-05 16-Aug K.IIC[160.03]QGFTGK.Q "sp|P53597|SUCA_HUMAN,tr|H7C233|H7C233_HUMAN,tr|A0A494C0D1|A0A494C0D1_HUMAN" 3 1022.5219 1.39 26691 9547 2 1022.522195 512.2682 "Succinate--CoA ligase [ADP\GDP-forming] subunit alpha, mitochondrial OS=Homo sapiens OX=9606 GN=SUCLG1 PE=1 SV=4" 8.22 2175.8 - 7.59E+06 - - - 0.2865 - 1.673 0.52 - 157.5 1 2 0 0.0003 9 0 0 0 2.77E+08 1.99E+08 - - - 4.3704 0.9952 221125_WJC_METTL3_EV_vs_WT_F03.09552.09552.2 0.0548 14-Aug K.VIQEIVDK.S "sp|P51114|FXR1_HUMAN,sp|P51116|FXR2_HUMAN,tr|E7EU85|E7EU85_HUMAN,tr|E9PFF5|E9PFF5_HUMAN,tr|B4DXZ6|B4DXZ6_HUMAN" 5 942.5386 1.38 26694 9552 2 942.53682 472.2766 Fragile X mental retardation syndrome-related protein 1 OS=Homo sapiens OX=9606 GN=FXR1 PE=1 SV=3 4.37 2176.3 - 1.89E+07 - - - -1.8853 - 1.223 0.27 - 221.8 1 2 0 -0.0018 8 0 0 0 9.78E+08 7.10E+08 - - - 1.6418 0.9997 221125_WJC_METTL3_EV_vs_WT_F03.09553.09553.2 0.0378 18-Nov R.YLAEVATGEK[136.11].R sp|P61981|1433G_HUMAN 1 1087.5641 1.1 26695 9553 2 1087.562516 544.7893 14-3-3 protein gamma OS=Homo sapiens OX=9606 GN=YWHAG PE=1 SV=2 4.53 2176.4 - 3.52E+06 - - - -1.4473 - 2.081 0.418 - 333.3 1 2 0 -0.0016 10 0 0 0 1.41E+08 1.28E+08 - - - 4.1735 0.9989 221125_WJC_METTL3_EV_vs_WT_F03.09555.09555.2 0.0141 22-Sep R.MAATPGAATYVK[136.11].T "sp|Q7Z589|EMSY_HUMAN,tr|H0YDI4|H0YDI4_HUMAN,tr|E9PPE6|E9PPE6_HUMAN,tr|E9PMC9|E9PMC9_HUMAN" 4 1187.61 0.61 26697 9555 2 1187.607888 594.8123 BRCA2-interacting transcriptional repressor EMSY OS=Homo sapiens OX=9606 GN=EMSY PE=1 SV=2 8.34 2176.5 - 438490 - - - -1.7742 - 1.752 0.315 - 213.1 1 2 0 -0.0021 12 0 0 0 7.79E+06 1.27E+07 - - - 2.8424 0.9995 221125_WJC_METTL3_EV_vs_WT_F03.09561.09561.2 9.25 18-Dec R.SLEEAEAYSR.S sp|Q6KB66|K2C80_HUMAN 1 1153.5251 408.89 26700 9561 2 1153.524181 577.7698 "Keratin, type II cytoskeletal 80 OS=Homo sapiens OX=9606 GN=KRT80 PE=1 SV=2" 4.25 2177.2 - 1.69E+06 - - - -0.8244 - 2.043 0.298 - 478.4 1 2 0 -0.001 10 0 0 0 1.13E+08 2.76E+05 - - - 3.2359 0.9988 221125_WJC_METTL3_EV_vs_WT_F03.09566.09566.2 0.153 14-Jul R.IFEPPPPK.K sp|O43143|DHX15_HUMAN 1 923.5117 1.33 26702 9566 2 923.511062 462.7631 Pre-mRNA-splicing factor ATP-dependent RNA helicase DHX15 OS=Homo sapiens OX=9606 GN=DHX15 PE=1 SV=2 6 2177.9 - 1.12E+06 - - - -0.641 - 1.442 0.286 - 162 1 2 0 -0.0006 8 0 0 0 1.65E+08 1.24E+08 - - - 2.2571 1 221125_WJC_METTL3_EV_vs_WT_F03.09567.09567.2 6.33E-05 20-Dec K.FAEALGSTEAK.A "sp|P78347|GTF2I_HUMAN,tr|A0A494C0Q7|A0A494C0Q7_HUMAN,tr|A0A494C1K3|A0A494C1K3_HUMAN" 3 1122.5557 1.41 26703 9567 2 1122.551229 562.2851 General transcription factor II-I OS=Homo sapiens OX=9606 GN=GTF2I PE=1 SV=2 4.53 2178 - 752222 - - - -3.9864 - 2.59 0.561 - 431.5 1 2 0 -0.0045 11 0 0 0 2.27E+09 1.61E+09 - - - 5.7576 0.9984 221125_WJC_METTL3_EV_vs_WT_F03.09570.09570.2 0.00119 16-Aug R.GTTVYLC[160.03]EK.R "sp|Q9Y2L1|RRP44_HUMAN,tr|F2Z2C0|F2Z2C0_HUMAN,tr|G3V1J5|G3V1J5_HUMAN" 3 1069.5114 1.62 26704 9570 2 1069.513714 535.763 Exosome complex exonuclease RRP44 OS=Homo sapiens OX=9606 GN=DIS3 PE=1 SV=2 5.99 2178.4 - 562826 - - - 2.1664 - 1.466 0.362 - 220 1 2 0 0.0023 9 0 0 0 3.65E+07 2.25E+07 - - - 2.8207 0.9702 221125_WJC_METTL3_EV_vs_WT_F03.09572.09572.2 0.0835 12-Jun R.GTFANIR.L sp|P21399|ACOHC_HUMAN 1 777.4133 9.46 26705 9572 2 777.412133 389.7139 Cytoplasmic aconitate hydratase OS=Homo sapiens OX=9606 GN=ACO1 PE=1 SV=3 9.75 2178.6 - 1.96E+06 - - - -1.5487 - 1.267 0.055 - 119.9 1 2 0 -0.0012 7 0 0 0 5.71E+07 6.04E+06 - - - 0.1967 0.9969 221125_WJC_METTL3_EV_vs_WT_F03.09575.09575.2 0.419 14-Dec R.TPTGFYDR[166.11].V sp|Q93100|KPBB_HUMAN 1 965.4482 0.8 26706 9575 2 965.446705 483.7314 Phosphorylase b kinase regulatory subunit beta OS=Homo sapiens OX=9606 GN=PHKB PE=1 SV=3 5.5 2179 - 1.54E+06 - - - -1.5651 - 1.866 0.121 - 625.6 1 2 0 -0.0015 8 0 0 0 4.24E+07 5.32E+07 - - - 1.8156 0.9996 221125_WJC_METTL3_EV_vs_WT_F03.09577.09577.2 0.0046 16-Jul K.AELDDTPMR[166.11].G sp|P23246|SFPQ_HUMAN 1 1056.4785 1.14 26707 9577 2 1056.477602 529.2465 "Splicing factor, proline- and glutamine-rich OS=Homo sapiens OX=9606 GN=SFPQ PE=1 SV=2" 4.03 2179.2 - 5.17E+06 - - - -0.8784 - 1.646 0.382 - 245.4 1 2 0 -0.0009 9 0 0 0 3.88E+08 3.39E+08 - - - 3.3039 0.9977 221125_WJC_METTL3_EV_vs_WT_F03.09584.09584.2 0.376 14-Aug K.IASFPTAK.Y "sp|Q12849|GRSF1_HUMAN,tr|H0YAK1|H0YAK1_HUMAN,tr|H0Y8R1|H0Y8R1_HUMAN,tr|F5H5I6|F5H5I6_HUMAN" 4 833.4647 1.07 26709 9584 2 833.464661 417.7396 G-rich sequence factor 1 OS=Homo sapiens OX=9606 GN=GRSF1 PE=1 SV=3 8.75 2180.1 - 1.57E+06 - - - -0.0516 - 1.579 0.172 - 164.9 1 2 0 0 8 0 0 0 1.30E+08 1.21E+08 - - - 1.689 0.9996 221125_WJC_METTL3_EV_vs_WT_F03.09586.09586.2 0.00396 18-Nov K.IASQMITEGR.M "sp|Q9BT78|CSN4_HUMAN,tr|D6RD63|D6RD63_HUMAN,tr|D6RFN0|D6RFN0_HUMAN,tr|D6RAX7|D6RAX7_HUMAN" 4 1104.5597 0.94 26711 9586 2 1104.557703 553.2871 COP9 signalosome complex subunit 4 OS=Homo sapiens OX=9606 GN=COPS4 PE=1 SV=1 6 2180.3 - 923618 - - - -1.8478 - 1.971 0.411 - 445.3 1 2 0 -0.002 10 0 0 0 3.25E+07 3.47E+07 - - - 3.97 0.9993 221125_WJC_METTL3_EV_vs_WT_F03.09592.09592.2 0.0134 14-Aug K.VIQEIVDK[136.11].S "sp|P51114|FXR1_HUMAN,sp|P51116|FXR2_HUMAN,tr|E7EU85|E7EU85_HUMAN,tr|E9PFF5|E9PFF5_HUMAN,tr|B4DXZ6|B4DXZ6_HUMAN" 5 950.5528 2.37 26713 9592 2 950.552227 476.2837 Fragile X mental retardation syndrome-related protein 1 OS=Homo sapiens OX=9606 GN=FXR1 PE=1 SV=3 4.37 2181.2 - 1.78E+07 - - - -0.5997 - 1.582 0.313 - 223.1 1 2 0 -0.0006 8 0 0 0 1.78E+09 7.51E+08 - - - 2.736 0.9578 221125_WJC_METTL3_EV_vs_WT_F03.09594.09594.2 15.3 14-Jun K.EVGSIIGK.K "sp|P57721|PCBP3_HUMAN,sp|P57723|PCBP4_HUMAN,sp|Q15366|PCBP2_HUMAN,sp|Q15365|PCBP1_HUMAN,tr|F8VTZ0|F8VTZ0_HUMAN,tr|C9JTY5|C9JTY5_HUMAN,tr|C9J7A9|C9J7A9_HUMAN,tr|F8W1G6|F8W1G6_HUMAN,tr|E9PFP8|E9PFP8_HUMAN,tr|C9IZV9|C9IZV9_HUMAN,tr|C9J0A4|C9J0A4_HUMAN,tr|J3QT27|J3QT27_HUMAN,tr|F8VZX2|F8VZX2_HUMAN,tr|F8W0G4|F8W0G4_HUMAN,tr|H3BSP4|H3BSP4_HUMAN,tr|C9J5V4|C9J5V4_HUMAN,tr|C9K0A2|C9K0A2_HUMAN,tr|C9JZY3|C9JZY3_HUMAN,tr|F8WC71|F8WC71_HUMAN,tr|C9JSA6|C9JSA6_HUMAN,tr|H3BRU6|H3BRU6_HUMAN" 21 801.4596 1 26714 9594 2 801.459537 401.7371 Poly(rC)-binding protein 3 OS=Homo sapiens OX=9606 GN=PCBP3 PE=1 SV=2 6.1 2181.4 - 2.20E+07 - - - -0.1023 - 1.139 0.05 - 145.7 2 2 0 -0.0001 8 0 0 0 1.08E+09 1.08E+09 - - - -0.3317 0.9759 221125_WJC_METTL3_EV_vs_WT_F03.09595.09595.2 1.82 14-Jun K.MINTDLSR[166.11].L "sp|P36578|RL4_HUMAN,tr|H3BM89|H3BM89_HUMAN" 2 958.4781 0.71 26715 9595 2 958.47709 480.2463 60S ribosomal protein L4 OS=Homo sapiens OX=9606 GN=RPL4 PE=1 SV=5 5.59 2181.5 - 3.91E+06 - - - -1.0913 - 1.159 0.112 - 88.2 2 2 0 -0.001 8 0 0 0 9.66E+07 1.36E+08 - - - 0.1785 0.9869 221125_WJC_METTL3_EV_vs_WT_F03.09596.09596.2 5.40E-05 13/16 K.TPGYVVTPH.T "sp|P47897|SYQ_HUMAN,tr|B4DDN1|B4DDN1_HUMAN,tr|C9J165|C9J165_HUMAN,tr|A0A0U1RQT0|A0A0U1RQT0_HUMAN,tr|A0A1B0GVU9|A0A1B0GVU9_HUMAN,tr|A0A0U1RR66|A0A0U1RR66_HUMAN" 6 969.492 - 26716 9596 2 969.490124 485.7533 Glutamine--tRNA ligase OS=Homo sapiens OX=9606 GN=QARS1 PE=1 SV=1 6.4 2181.6 - 1.87E+06 - - - -1.9165 - 1.998 0.544 - 477.3 1 1 0 -0.0019 9 0 0 0 - - - - - 5.0608 0.9969 221125_WJC_METTL3_EV_vs_WT_F03.09597.09597.2 0.0123 18-Aug R.IDGGITGNMR.Q "sp|Q14839|CHD4_HUMAN,tr|A0A2R8Y4X2|A0A2R8Y4X2_HUMAN,tr|A0A2U3TZM0|A0A2U3TZM0_HUMAN,tr|A0A2R8Y685|A0A2R8Y685_HUMAN,tr|A0A2R8Y445|A0A2R8Y445_HUMAN,tr|A0A2R8YD40|A0A2R8YD40_HUMAN,tr|A0A2R8Y5J0|A0A2R8Y5J0_HUMAN,tr|A0A2R8Y425|A0A2R8Y425_HUMAN,tr|A0A2R8YFK9|A0A2R8YFK9_HUMAN,tr|A0A2R8Y8B3|A0A2R8Y8B3_HUMAN,tr|A0A2R8Y8C1|A0A2R8Y8C1_HUMAN,tr|A0A0C4DGG9|A0A0C4DGG9_HUMAN,tr|A0A2R8YFD8|A0A2R8YFD8_HUMAN,tr|A0A2R8YDW2|A0A2R8YDW2_HUMAN,tr|A0A2R8Y5Z7|A0A2R8Y5Z7_HUMAN,tr|F5GWX5|F5GWX5_HUMAN,tr|A0A2R8YER1|A0A2R8YER1_HUMAN,tr|A0A2R8Y521|A0A2R8Y521_HUMAN,tr|A0A2R8YDJ9|A0A2R8YDJ9_HUMAN,tr|A0A2R8Y212|A0A2R8Y212_HUMAN" 20 1032.5022 1.2 26717 9597 2 1032.5044 517.2584 Chromodomain-helicase-DNA-binding protein 4 OS=Homo sapiens OX=9606 GN=CHD4 PE=1 SV=2 5.84 2181.6 - 1.18E+06 - - - 2.1027 - 1.49 0.274 - 131.8 1 2 0 0.0022 10 0 0 0 5.00E+07 4.17E+07 - - - 2.1772 0.9998 221125_WJC_METTL3_EV_vs_WT_F03.09600.09600.2 0.00104 18-Oct R.QTGSPGMIYR.N "tr|K7EKU4|K7EKU4_HUMAN,tr|A0A590UJV4|A0A590UJV4_HUMAN,tr|A0A590UJJ4|A0A590UJJ4_HUMAN,tr|A0A590UJK5|A0A590UJK5_HUMAN,tr|A0A590UK89|A0A590UK89_HUMAN,tr|A0A590UJX9|A0A590UJX9_HUMAN" 6 1108.5335 0.57 26718 9600 2 1108.534502 555.274 Voltage-gated potassium channel subunit beta-2 OS=Homo sapiens OX=9606 GN=KCNAB2 PE=1 SV=2 8.75 2182 - 510258 - - - 0.8777 - 1.806 0.46 - 347.1 1 2 0 0.001 10 0 0 0 5.50E+07 9.61E+07 - - - 4.0882 0.9871 221125_WJC_METTL3_EV_vs_WT_F03.09602.09602.2 4.15 12-May K.DNNLLGR.F "sp|P0DMV8|HS71A_HUMAN,sp|P34931|HS71L_HUMAN,sp|P0DMV9|HS71B_HUMAN,sp|P17066|HSP76_HUMAN,tr|Q53FA3|Q53FA3_HUMAN,tr|V9GZ37|V9GZ37_HUMAN,tr|A0A0G2JIW1|A0A0G2JIW1_HUMAN" 7 800.4141 0.14 26719 9602 2 800.414575 401.2143 Heat shock 70 kDa protein 1A OS=Homo sapiens OX=9606 GN=HSPA1A PE=1 SV=1 5.84 2182.2 - 3.05E+07 - - - 0.6359 - 1.228 0.114 - 151.3 1 2 0 0.0005 7 0 0 0 2.96E+09 2.16E+10 - - - 0.5336 0.9998 221125_WJC_METTL3_EV_vs_WT_F03.09603.09603.2 9.11E-05 16-Oct R.TELSPAQIK[136.11].Q sp|Q7Z3B4|NUP54_HUMAN 1 993.5586 1.79 26720 9603 2 993.559162 497.7866 Nucleoporin p54 OS=Homo sapiens OX=9606 GN=NUP54 PE=1 SV=2 5.66 2182.3 - 5.12E+06 - - - 0.5546 - 1.872 0.427 - 397.5 1 2 0 0.0006 9 0 0 0 4.53E+08 2.53E+08 - - - 4.0086 0.9997 221125_WJC_METTL3_EV_vs_WT_F03.09606.09606.2 0.000232 14-Sep R.YTAAVPYR.L "sp|Q9UBM7|DHCR7_HUMAN,tr|A0A804HI25|A0A804HI25_HUMAN,tr|A0A804HJQ7|A0A804HJQ7_HUMAN" 3 939.4814 1.29 26721 9606 2 939.479913 470.748 7-dehydrocholesterol reductase OS=Homo sapiens OX=9606 GN=DHCR7 PE=1 SV=1 8.59 2182.6 - 4.07E+06 - - - -1.6009 - 1.628 0.488 - 316.8 1 2 0 -0.0015 8 0 0 0 1.10E+08 8.53E+07 - - - 4.1147 0.9922 221125_WJC_METTL3_EV_vs_WT_F03.09607.09607.2 0.016 14-Jun R.AVPFNAPK[136.11].- sp|Q96CT7|CC124_HUMAN 1 850.4792 0.93 26722 9607 2 850.477324 426.2469 Coiled-coil domain-containing protein 124 OS=Homo sapiens OX=9606 GN=CCDC124 PE=1 SV=1 8.8 2182.7 - 2.79E+06 - - - -2.2505 - 1.183 0.26 - 157.5 1 2 0 -0.0019 8 0 0 0 2.79E+08 3.00E+08 - - - 1.4676 0.9956 221125_WJC_METTL3_EV_vs_WT_F03.09608.09608.2 0.107 16-Jun K.VSSTGLSLK[136.11].K sp|Q16352|AINX_HUMAN 1 898.5215 1.76 26723 9608 2 898.519924 450.268 Alpha-internexin OS=Homo sapiens OX=9606 GN=INA PE=1 SV=2 8.72 2182.7 - 2.30E+06 - - - -1.7507 - 1.466 0.22 - 72.9 2 2 0 -0.0016 9 0 0 0 1.42E+08 8.07E+07 - - - 1.6377 0.9997 221125_WJC_METTL3_EV_vs_WT_F03.09611.09611.2 6.78E-05 16-Sep R.TELSPAQIK.Q sp|Q7Z3B4|NUP54_HUMAN 1 985.5444 1.8 26725 9611 2 985.545029 493.7795 Nucleoporin p54 OS=Homo sapiens OX=9606 GN=NUP54 PE=1 SV=2 5.66 2183.1 - 1.03E+07 - - - 0.6271 - 1.714 0.402 - 319.7 1 2 0 0.0006 9 0 0 0 4.60E+08 2.56E+08 - - - 3.5688 0.9991 221125_WJC_METTL3_EV_vs_WT_F03.09617.09617.2 0.0855 18-Oct R.SMVEEGTGLR.L "sp|Q15149|PLEC_HUMAN,tr|H0YDN1|H0YDN1_HUMAN" 2 1077.5125 1.93 26728 9617 2 1077.515099 539.7635 Plectin OS=Homo sapiens OX=9606 GN=PLEC PE=1 SV=3 4.53 2183.7 - 1.50E+06 - - - 2.4501 - 2.006 0.36 - 458.8 1 2 0 0.0026 10 0 0 0 5.06E+07 2.62E+07 - - - 3.6423 0.9994 221125_WJC_METTL3_EV_vs_WT_F03.09624.09624.2 0.00555 14-Jul R.LWDC[160.03]ETGK.Q "sp|Q13347|EIF3I_HUMAN,tr|A0A7I2YQT9|A0A7I2YQT9_HUMAN,tr|A0A7I2V613|A0A7I2V613_HUMAN,tr|A0A7I2V3N2|A0A7I2V3N2_HUMAN,tr|A0A7I2YQI6|A0A7I2YQI6_HUMAN,tr|A0A7I2YQF8|A0A7I2YQF8_HUMAN,tr|Q5TFK1|Q5TFK1_HUMAN,tr|A0A7I2V3U3|A0A7I2V3U3_HUMAN,tr|A0A7I2V607|A0A7I2V607_HUMAN,tr|A0A7I2V640|A0A7I2V640_HUMAN,tr|A0A7P0MRT9|A0A7P0MRT9_HUMAN,tr|A0A7I2V3K6|A0A7I2V3K6_HUMAN,tr|A0A7I2V4S8|A0A7I2V4S8_HUMAN,tr|A0A7I2V5V8|A0A7I2V5V8_HUMAN,tr|A0A7I2V391|A0A7I2V391_HUMAN,tr|A0A7I2YQN1|A0A7I2YQN1_HUMAN,tr|A0A7I2V2M3|A0A7I2V2M3_HUMAN,tr|A0A7I2YQP9|A0A7I2YQP9_HUMAN,tr|A0A7I2YQI2|A0A7I2YQI2_HUMAN,tr|A0A7I2YQC8|A0A7I2YQC8_HUMAN,tr|A0A7I2V685|A0A7I2V685_HUMAN" 21 1007.4382 1.14 26731 9624 2 1007.438478 504.7264 Eukaryotic translation initiation factor 3 subunit I OS=Homo sapiens OX=9606 GN=EIF3I PE=1 SV=1 4.37 2184.6 - 1.13E+06 - - - 0.2442 - 1.255 0.428 - 148.4 1 2 0 0.0002 8 0 0 0 6.72E+07 5.88E+07 - - - 2.8872 0.987 221125_WJC_METTL3_EV_vs_WT_F03.09629.09629.2 0.00537 14-Jul R.AVPFNAPK.- sp|Q96CT7|CC124_HUMAN 1 842.465 0.9 26734 9629 2 842.46108 422.2398 Coiled-coil domain-containing protein 124 OS=Homo sapiens OX=9606 GN=CCDC124 PE=1 SV=1 8.8 2185.2 - 4.23E+06 - - - -4.6981 - 1.408 0.331 - 145.6 1 2 0 -0.004 8 0 0 0 2.69E+08 3.00E+08 - - - 2.5165 0.9999 221125_WJC_METTL3_EV_vs_WT_F03.09630.09630.2 0.00334 16-Oct K.MAYEYADER.L sp|O60783|RT14_HUMAN 1 1146.4652 1.85 26735 9630 2 1146.464057 574.2399 "28S ribosomal protein S14, mitochondrial OS=Homo sapiens OX=9606 GN=MRPS14 PE=1 SV=1" 4.14 2185.3 - 2.07E+06 - - - -0.9743 - 2.007 0.594 - 322.1 1 2 0 -0.0011 9 0 0 0 5.34E+07 2.89E+07 - - - 5.4434 0.9988 221125_WJC_METTL3_EV_vs_WT_F03.09631.09631.2 0.0272 14-Aug R.LWDC[160.03]ETGK[136.11].Q "sp|Q13347|EIF3I_HUMAN,tr|A0A7I2YQT9|A0A7I2YQT9_HUMAN,tr|A0A7I2V613|A0A7I2V613_HUMAN,tr|A0A7I2V3N2|A0A7I2V3N2_HUMAN,tr|A0A7I2YQI6|A0A7I2YQI6_HUMAN,tr|A0A7I2YQF8|A0A7I2YQF8_HUMAN,tr|Q5TFK1|Q5TFK1_HUMAN,tr|A0A7I2V3U3|A0A7I2V3U3_HUMAN,tr|A0A7I2V607|A0A7I2V607_HUMAN,tr|A0A7I2V640|A0A7I2V640_HUMAN,tr|A0A7P0MRT9|A0A7P0MRT9_HUMAN,tr|A0A7I2V3K6|A0A7I2V3K6_HUMAN,tr|A0A7I2V4S8|A0A7I2V4S8_HUMAN,tr|A0A7I2V5V8|A0A7I2V5V8_HUMAN,tr|A0A7I2V391|A0A7I2V391_HUMAN,tr|A0A7I2YQN1|A0A7I2YQN1_HUMAN,tr|A0A7I2V2M3|A0A7I2V2M3_HUMAN,tr|A0A7I2YQP9|A0A7I2YQP9_HUMAN,tr|A0A7I2YQI2|A0A7I2YQI2_HUMAN,tr|A0A7I2YQC8|A0A7I2YQC8_HUMAN,tr|A0A7I2V685|A0A7I2V685_HUMAN" 21 1015.4524 1.14 26736 9631 2 1015.452947 508.7335 Eukaryotic translation initiation factor 3 subunit I OS=Homo sapiens OX=9606 GN=EIF3I PE=1 SV=1 4.37 2185.4 - 1.57E+06 - - - 0.5072 - 1.424 0.292 - 196 1 2 0 0.0005 8 0 0 0 6.68E+07 5.88E+07 - - - 2.2636 0.9998 221125_WJC_METTL3_EV_vs_WT_F03.09632.09632.2 5.92E-05 16-Oct K.MAYEYADER[166.11].L sp|O60783|RT14_HUMAN 1 1156.4734 1.85 26737 9632 2 1156.470766 579.244 "28S ribosomal protein S14, mitochondrial OS=Homo sapiens OX=9606 GN=MRPS14 PE=1 SV=1" 4.14 2185.5 - 1.04E+06 - - - -2.3157 - 1.889 0.633 - 451.2 1 2 0 -0.0027 9 0 0 0 5.33E+07 2.89E+07 - - - 5.5556 0.9696 221125_WJC_METTL3_EV_vs_WT_F03.09633.09633.2 0.00809 16-Sep H.FYASQMAQR.K sp|Q9NZI8|IF2B1_HUMAN 1 1100.5073 0.81 26738 9633 2 1100.507063 551.2609 Insulin-like growth factor 2 mRNA-binding protein 1 OS=Homo sapiens OX=9606 GN=IGF2BP1 PE=1 SV=2 8.75 2185.6 - 802469 - - - -0.2281 - 1.606 0.347 - 259.8 1 1 0 -0.0003 9 0 0 0 1.34E+07 1.66E+07 - - - 2.9744 0.9901 221125_WJC_METTL3_EV_vs_WT_F03.09638.09638.2 0.198 16-Jul K.VSSTGLSLK.K sp|Q16352|AINX_HUMAN 1 890.5073 1.76 26741 9638 2 890.505465 446.2609 Alpha-internexin OS=Homo sapiens OX=9606 GN=INA PE=1 SV=2 8.72 2186.2 - 4.30E+06 - - - -2.0573 - 1.363 0.188 - 93.9 2 2 0 -0.0018 9 0 0 0 1.42E+08 8.07E+07 - - - 1.1905 0.9561 221125_WJC_METTL3_EV_vs_WT_F03.09639.09639.2 0.00956 14-Aug Y.TSVTPVLR.G "sp|P26599|PTBP1_HUMAN,tr|A0A6Q8PEX4|A0A6Q8PEX4_HUMAN,tr|A0A0U1RRM4|A0A0U1RRM4_HUMAN,tr|A6NLN1|A6NLN1_HUMAN,tr|K7EKJ7|K7EKJ7_HUMAN,tr|K7ES59|K7ES59_HUMAN,tr|A0A7I2V4H6|A0A7I2V4H6_HUMAN,tr|A0A7I2V621|A0A7I2V621_HUMAN" 8 871.5127 0.92 26742 9639 2 871.511859 436.7636 Polypyrimidine tract-binding protein 1 OS=Homo sapiens OX=9606 GN=PTBP1 PE=1 SV=1 9.41 2186.3 - 3.47E+06 - - - -0.9845 - 1.572 0.321 - 317.2 1 1 0 -0.0009 8 0 0 0 1.10E+08 1.20E+08 - - - 2.7759 0.9962 221125_WJC_METTL3_EV_vs_WT_F03.09641.09641.2 0.0304 14-Aug K.GVIPMNAK.D sp|Q9Y3I0|RTCB_HUMAN 1 828.4528 2.33 26744 9641 2 828.451057 415.2337 RNA-splicing ligase RtcB homolog OS=Homo sapiens OX=9606 GN=RTCB PE=1 SV=1 8.75 2186.4 - 1.70E+06 - - - -2.0544 - 1.486 0.229 - 165.5 1 2 0 -0.0017 8 0 0 0 7.90E+07 3.39E+07 - - - 1.9264 0.9999 221125_WJC_METTL3_EV_vs_WT_F03.09652.09652.2 1.09E-06 13/20 K.FAEALGSTEAK[136.11].A "sp|P78347|GTF2I_HUMAN,tr|A0A494C0Q7|A0A494C0Q7_HUMAN,tr|A0A494C1K3|A0A494C1K3_HUMAN" 3 1130.5699 1.4 26750 9652 2 1130.568172 566.2922 General transcription factor II-I OS=Homo sapiens OX=9606 GN=GTF2I PE=1 SV=2 4.53 2187.7 - 4.71E+07 - - - -1.532 - 2.459 0.542 - 510.7 1 2 0 -0.0017 11 0 0 0 2.25E+09 1.61E+09 - - - 5.4777 0.9958 221125_WJC_METTL3_EV_vs_WT_F03.09654.09654.2 0.0521 18-Jul K.IEPIPGESPK.M "sp|O60841|IF2P_HUMAN,tr|A0A087WUT6|A0A087WUT6_HUMAN" 2 1065.5706 0.92 26751 9654 2 1065.571038 533.7926 Eukaryotic translation initiation factor 5B OS=Homo sapiens OX=9606 GN=EIF5B PE=1 SV=4 4.53 2187.9 - 443570 - - - 0.3866 - 1.254 0.216 - 124.7 1 2 0 0.0004 10 0 0 0 4.92E+07 5.33E+07 - - - 1.268 0.9991 221125_WJC_METTL3_EV_vs_WT_F03.09656.09656.2 0.000287 20-Sep R.AFDGAGSSLGR.A sp|Q8WUF5|IASPP_HUMAN 1 1036.4938 1.51 26752 9656 2 1036.496668 519.2542 RelA-associated inhibitor OS=Homo sapiens OX=9606 GN=PPP1R13L PE=1 SV=4 5.88 2188.1 - 2.24E+06 - - - 2.794 - 1.586 0.482 - 249.1 1 2 0 0.0029 11 0 0 0 6.19E+07 4.10E+07 - - - 3.8478 0.9991 221125_WJC_METTL3_EV_vs_WT_F03.09658.09658.2 4.31E-05 20-Oct R.YAPGTLGQPPR.Q "sp|P31269|HXA9_HUMAN,tr|A0A669K9T0|A0A669K9T0_HUMAN,tr|A8MVF3|A8MVF3_HUMAN,tr|A0A669KBC8|A0A669KBC8_HUMAN" 4 1155.6037 5.3 26754 9658 2 1155.599867 578.8091 Homeobox protein Hox-A9 OS=Homo sapiens OX=9606 GN=HOXA9 PE=1 SV=4 8.75 2188.3 - 686370 - - - -3.2797 - 1.794 0.509 - 318.8 1 2 0 -0.0038 11 0 0 0 2.14E+07 4.04E+06 - - - 4.3804 0.9979 221125_WJC_METTL3_EV_vs_WT_F03.09663.09663.2 0.00203 18-Aug K.IEPIPGESPK[136.11].M "sp|O60841|IF2P_HUMAN,tr|A0A087WUT6|A0A087WUT6_HUMAN" 2 1073.5848 0.95 26757 9663 2 1073.582287 537.7997 Eukaryotic translation initiation factor 5B OS=Homo sapiens OX=9606 GN=EIF5B PE=1 SV=4 4.53 2188.9 - 957270 - - - -2.365 - 1.401 0.356 - 193.9 1 2 0 -0.0025 10 0 0 0 4.92E+07 5.21E+07 - - - 2.6108 0.9749 221125_WJC_METTL3_EV_vs_WT_F03.09664.09664.2 0.216 16-Jul K.LVPLK[136.11]ETIK[136.11].G sp|P06576|ATPB_HUMAN 1 1055.6925 1.74 26758 9664 2 1055.692127 528.8535 "ATP synthase subunit beta, mitochondrial OS=Homo sapiens OX=9606 GN=ATP5F1B PE=1 SV=3" 8.59 2189 - 1.13E+06 - - - -0.3836 - 1.379 0.233 - 120.6 1 2 1 -0.0004 9 0 0 0 8.12E+07 4.67E+07 - - - 1.6915 0.9997 221125_WJC_METTL3_EV_vs_WT_F03.09665.09665.2 0.00022 16-Sep R.ATLDEYTTR.V "sp|Q16656|NRF1_HUMAN,tr|C9JP85|C9JP85_HUMAN" 2 1068.5088 1.65 26759 9665 2 1068.507863 535.2617 Nuclear respiratory factor 1 OS=Homo sapiens OX=9606 GN=NRF1 PE=1 SV=1 4.37 2189.1 - 936368 - - - -0.8339 - 1.732 0.434 - 281.2 1 2 0 -0.0009 9 0 0 0 1.99E+08 1.20E+08 - - - 3.8353 0.9998 221125_WJC_METTL3_EV_vs_WT_F03.09666.09666.2 0.000129 24-Dec R.QLLAGTGPGGEAR.A "sp|Q9NP08|HMX1_HUMAN,tr|F1T0J4|F1T0J4_HUMAN" 2 1225.6415 1.91 26760 9666 2 1225.639668 613.828 Homeobox protein HMX1 OS=Homo sapiens OX=9606 GN=HMX1 PE=2 SV=2 6 2189.2 - 383144 - - - -1.4939 - 2.491 0.441 - 321.1 1 2 0 -0.0018 13 0 0 0 1.65E+07 8.60E+06 - - - 4.6401 0.9991 221125_WJC_METTL3_EV_vs_WT_F03.09673.09673.2 0.00873 18-Aug K.IYEAQPEISR.A sp|O60287|NPA1P_HUMAN 1 1204.6088 1.06 26765 9673 2 1204.60981 603.3117 Nucleolar pre-ribosomal-associated protein 1 OS=Homo sapiens OX=9606 GN=URB1 PE=1 SV=4 4.53 2190.2 - 355573 - - - 0.8368 - 1.534 0.331 - 129.8 1 2 0 0.001 10 0 0 0 6.44E+06 6.07E+06 - - - 2.6798 0.9999 221125_WJC_METTL3_EV_vs_WT_F03.09674.09674.2 0.000142 14/24 R.QLLAGTGPGGEAR[166.11].A "sp|Q9NP08|HMX1_HUMAN,tr|F1T0J4|F1T0J4_HUMAN" 2 1235.6498 1.91 26766 9674 2 1235.648704 618.8322 Homeobox protein HMX1 OS=Homo sapiens OX=9606 GN=HMX1 PE=2 SV=2 6 2190.3 - 252078 - - - -0.8619 - 2.591 0.503 - 764.5 1 2 0 -0.0011 13 0 0 0 1.65E+07 8.60E+06 - - - 5.1993 0.9997 221125_WJC_METTL3_EV_vs_WT_F03.09677.09677.2 0.0037 16-Jul R.ADGYVLEGK.E "sp|P62241|RS8_HUMAN,tr|Q5JR95|Q5JR95_HUMAN" 2 950.4709 0.85 26767 9677 2 950.470659 476.2427 40S ribosomal protein S8 OS=Homo sapiens OX=9606 GN=RPS8 PE=1 SV=2 4.37 2190.7 - 7.61E+06 - - - -0.2662 - 1.582 0.422 - 231.9 1 2 0 -0.0003 9 0 0 0 2.19E+08 2.58E+08 - - - 3.4848 0.9988 221125_WJC_METTL3_EV_vs_WT_F03.09681.09681.2 0.105 16-Aug K.NIAVETDVR.V "sp|Q9BVC5|ASHWN_HUMAN,tr|C9J4K0|C9J4K0_HUMAN" 2 1015.5298 1.61 26770 9681 2 1015.530095 508.7722 Ashwin OS=Homo sapiens OX=9606 GN=C2orf49 PE=1 SV=1 4.37 2191.2 - 1.44E+06 - - - 0.2669 - 1.447 0.293 - 168 1 2 0 0.0003 9 0 0 0 1.03E+08 6.40E+07 - - - 2.274 0.9997 221125_WJC_METTL3_EV_vs_WT_F03.09684.09684.2 0.00132 16-Oct K.TSTILAAAR.E "sp|P35249|RFC4_HUMAN,tr|C9JGY5|C9JGY5_HUMAN,tr|F8WE44|F8WE44_HUMAN,tr|C9JXZ7|C9JXZ7_HUMAN,tr|C9J8M3|C9J8M3_HUMAN,tr|C9JZI1|C9JZI1_HUMAN" 6 902.5185 0.46 26772 9684 2 902.51781 452.2665 Replication factor C subunit 4 OS=Homo sapiens OX=9606 GN=RFC4 PE=1 SV=2 9.41 2191.4 - 1.12E+06 - - - -0.7989 - 1.82 0.375 - 325.5 1 2 0 -0.0007 9 0 0 0 3.23E+07 7.03E+07 - - - 3.543 0.9426 221125_WJC_METTL3_EV_vs_WT_F03.09685.09685.2 0.229 16-Jun K.FIASTGMDR[166.11].S "sp|Q9UMS4|PRP19_HUMAN,tr|H0YGZ5|H0YGZ5_HUMAN" 2 1006.4781 1.04 26773 9685 2 1006.47416 504.2463 Pre-mRNA-processing factor 19 OS=Homo sapiens OX=9606 GN=PRPF19 PE=1 SV=1 5.84 2191.5 - 1.79E+06 - - - -3.9504 - 1.039 0.236 - 84.4 1 2 0 -0.004 9 0 0 0 5.39E+07 5.16E+07 - - - 0.8935 0.9978 221125_WJC_METTL3_EV_vs_WT_F03.09686.09686.2 0.00284 18-Sep K.IYEAQPEISR[166.11].A sp|O60287|NPA1P_HUMAN 1 1214.6171 1.06 26774 9686 2 1214.612283 608.3158 Nucleolar pre-ribosomal-associated protein 1 OS=Homo sapiens OX=9606 GN=URB1 PE=1 SV=4 4.53 2191.6 - 347869 - - - -3.9428 - 1.902 0.4 - 326.9 1 2 0 -0.0048 10 0 0 0 6.44E+06 6.07E+06 - - - 3.7884 0.9917 221125_WJC_METTL3_EV_vs_WT_F03.09687.09687.2 0.0399 20-Aug R.TLDSGTSEIVK.S sp|Q9H501|ESF1_HUMAN 1 1148.5925 0.32 26775 9687 2 1148.588255 575.3035 ESF1 homolog OS=Homo sapiens OX=9606 GN=ESF1 PE=1 SV=1 4.37 2191.8 - 305532 - - - -3.6819 - 1.624 0.258 - 124.3 1 2 0 -0.0042 11 0 0 0 4.14E+06 1.30E+07 - - - 2.257 0.9993 221125_WJC_METTL3_EV_vs_WT_F03.09690.09690.2 0.00133 14-Aug K.VGVNGFGR[166.11].L sp|P04406|G3P_HUMAN 1 814.4325 0.96 26776 9690 2 814.43054 408.2235 Glyceraldehyde-3-phosphate dehydrogenase OS=Homo sapiens OX=9606 GN=GAPDH PE=1 SV=3 9.72 2192.1 - 5.66E+07 - - - -2.414 - 1.773 0.423 - 148.5 1 2 0 -0.002 8 0 0 0 8.62E+09 8.94E+09 - - - 3.8918 0.9996 221125_WJC_METTL3_EV_vs_WT_F03.09691.09691.2 0.0045 14-Jul K.VGVNGFGR.L sp|P04406|G3P_HUMAN 1 804.4242 0.96 26777 9691 2 804.425866 403.2194 Glyceraldehyde-3-phosphate dehydrogenase OS=Homo sapiens OX=9606 GN=GAPDH PE=1 SV=3 9.72 2192.2 - 3.36E+07 - - - 2.0263 - 1.772 0.458 - 130.2 1 2 0 0.0016 8 0 0 0 8.60E+09 8.92E+09 - - - 4.1487 0.9914 221125_WJC_METTL3_EV_vs_WT_F03.09693.09693.2 0.00797 16-Aug K.LVPLKETIK.G sp|P06576|ATPB_HUMAN 1 1039.6641 1.74 26779 9693 2 1039.664181 520.8393 "ATP synthase subunit beta, mitochondrial OS=Homo sapiens OX=9606 GN=ATP5F1B PE=1 SV=3" 8.59 2192.3 - 2.24E+06 - - - 0.0471 - 1.567 0.306 - 187.8 1 2 1 0 9 0 0 0 8.12E+07 4.67E+07 - - - 2.6006 0.9997 221125_WJC_METTL3_EV_vs_WT_F03.09699.09699.2 5.39E-05 16-Aug R.GVYSEETLR[166.11].A "sp|Q16891|MIC60_HUMAN,tr|B9A067|B9A067_HUMAN,tr|A0A087WYS0|A0A087WYS0_HUMAN,tr|C9J406|C9J406_HUMAN,tr|H7C463|H7C463_HUMAN" 5 1062.5221 1.34 26783 9699 2 1062.521899 532.2683 MICOS complex subunit MIC60 OS=Homo sapiens OX=9606 GN=IMMT PE=1 SV=1 4.53 2193.1 - 2.98E+06 - - - -0.1976 - 1.907 0.348 - 188.7 1 2 0 -0.0002 9 0 0 0 1.00E+09 7.50E+08 - - - 3.4788 0.9996 221125_WJC_METTL3_EV_vs_WT_F03.09700.09700.2 0.017 16-Oct R.GVYSEETLR.A "sp|Q16891|MIC60_HUMAN,tr|B9A067|B9A067_HUMAN,tr|A0A087WYS0|A0A087WYS0_HUMAN,tr|C9J406|C9J406_HUMAN,tr|H7C463|H7C463_HUMAN" 5 1052.5138 1.34 26784 9700 2 1052.514011 527.2642 MICOS complex subunit MIC60 OS=Homo sapiens OX=9606 GN=IMMT PE=1 SV=1 4.53 2193.2 - 2.32E+06 - - - 0.1634 - 1.62 0.4 - 303.3 1 2 0 0.0002 9 0 0 0 1.00E+09 7.50E+08 - - - 3.391 0.9999 221125_WJC_METTL3_EV_vs_WT_F03.09701.09701.2 4.35E-05 16-Oct R.FGSGMNMGR[166.11].L "sp|P52272|HNRPM_HUMAN,tr|M0R019|M0R019_HUMAN,tr|M0QYL3|M0QYL3_HUMAN,tr|A0A087X0X3|A0A087X0X3_HUMAN,tr|M0QZM1|M0QZM1_HUMAN" 5 965.4087 1.5 26785 9701 2 965.40891 483.7116 Heterogeneous nuclear ribonucleoprotein M OS=Homo sapiens OX=9606 GN=HNRNPM PE=1 SV=3 9.75 2193.2 - 1.77E+06 - - - 0.2424 - 1.898 0.546 - 279.4 1 2 0 0.0002 9 0 0 0 8.25E+08 5.50E+08 - - - 4.9276 0.999 221125_WJC_METTL3_EV_vs_WT_F03.09702.09702.2 0.0105 16-Sep K.TSTILAAAR[166.11].E "sp|P35249|RFC4_HUMAN,tr|C9JGY5|C9JGY5_HUMAN,tr|F8WE44|F8WE44_HUMAN,tr|C9JXZ7|C9JXZ7_HUMAN,tr|C9J8M3|C9J8M3_HUMAN,tr|C9JZI1|C9JZI1_HUMAN" 6 912.5268 0.51 26786 9702 2 912.527097 457.2707 Replication factor C subunit 4 OS=Homo sapiens OX=9606 GN=RFC4 PE=1 SV=2 9.41 2193.3 - 1.76E+06 - - - 0.3244 - 1.437 0.318 - 243 1 2 0 0.0003 9 0 0 0 3.23E+07 6.33E+07 - - - 2.4386 0.9997 221125_WJC_METTL3_EV_vs_WT_F03.09707.09707.2 0.00241 22-Sep R.AVLIAGQPGTGK.T "sp|Q9Y230|RUVB2_HUMAN,tr|M0R0Y3|M0R0Y3_HUMAN,tr|M0QXI6|M0QXI6_HUMAN,tr|X6R2L4|X6R2L4_HUMAN" 4 1110.6397 0.97 26789 9707 2 1110.640155 556.3271 RuvB-like 2 OS=Homo sapiens OX=9606 GN=RUVBL2 PE=1 SV=3 8.8 2193.8 - 1.61E+06 - - - 0.4025 - 2.116 0.377 - 257.1 1 2 0 0.0004 12 0 0 0 1.78E+08 1.83E+08 - - - 3.7975 0.9966 221125_WJC_METTL3_EV_vs_WT_F03.09708.09708.2 0.482 16-Aug R.ILQDSLGGR.T "sp|P52732|KIF11_HUMAN,tr|A0A7I2YQY4|A0A7I2YQY4_HUMAN,tr|A0A7I2V3A9|A0A7I2V3A9_HUMAN,tr|A0A7I2V3V3|A0A7I2V3V3_HUMAN" 4 957.5243 4.15 26790 9708 2 957.524379 479.7694 Kinesin-like protein KIF11 OS=Homo sapiens OX=9606 GN=KIF11 PE=1 SV=2 5.84 2193.8 - 9.15E+06 - - - 0.0366 - 1.465 0.167 - 188.7 1 2 0 0 9 0 0 0 4.65E+09 1.12E+09 - - - 1.3792 0.9992 221125_WJC_METTL3_EV_vs_WT_F03.09713.09713.2 0.023 16-Sep R.ILQDSLGGR[166.11].T "sp|P52732|KIF11_HUMAN,tr|A0A7I2YQY4|A0A7I2YQY4_HUMAN,tr|A0A7I2V3A9|A0A7I2V3A9_HUMAN,tr|A0A7I2V3V3|A0A7I2V3V3_HUMAN" 4 967.5326 4.15 26793 9713 2 967.53372 484.7736 Kinesin-like protein KIF11 OS=Homo sapiens OX=9606 GN=KIF11 PE=1 SV=2 5.84 2194.4 - 4.67E+06 - - - 1.1431 - 1.79 0.288 - 249.9 1 2 0 0.0011 9 0 0 0 4.65E+09 1.12E+09 - - - 2.8522 0.9982 221125_WJC_METTL3_EV_vs_WT_F03.09714.09714.2 0.0603 16-Jun K.FIASTGMDR.S "sp|Q9UMS4|PRP19_HUMAN,tr|H0YGZ5|H0YGZ5_HUMAN" 2 996.4699 1.04 26794 9714 2 996.469044 499.2422 Pre-mRNA-processing factor 19 OS=Homo sapiens OX=9606 GN=PRPF19 PE=1 SV=1 5.84 2194.4 - 2.60E+06 - - - -0.8249 - 1.172 0.336 - 82.4 1 2 0 -0.0008 9 0 0 0 5.39E+07 5.16E+07 - - - 1.9816 0.8648 221125_WJC_METTL3_EV_vs_WT_F03.09715.09715.2 9.83 14-May R.LTDELQVK.E "tr|A0A590UJ28|A0A590UJ28_HUMAN,tr|A0A590UK05|A0A590UK05_HUMAN,tr|A0A590UKA6|A0A590UKA6_HUMAN,tr|A0A590UKA3|A0A590UKA3_HUMAN,tr|A0A590UJL9|A0A590UJL9_HUMAN,tr|A0A590UJI4|A0A590UJI4_HUMAN,tr|A0A590UJ77|A0A590UJ77_HUMAN,tr|A0A590UJC1|A0A590UJC1_HUMAN,tr|A0A590UJ83|A0A590UJ83_HUMAN,tr|A0A590UJC6|A0A590UJC6_HUMAN,tr|A0A2U3TZI4|A0A2U3TZI4_HUMAN,tr|A0A590UK19|A0A590UK19_HUMAN,tr|A0A590UJW7|A0A590UJW7_HUMAN,tr|A0A590UJ69|A0A590UJ69_HUMAN,tr|A0A590UK35|A0A590UK35_HUMAN,tr|A0A590UJA8|A0A590UJA8_HUMAN" 16 944.5179 0.42 26795 9715 2 944.517751 473.2662 Coiled-coil domain-containing protein 30 OS=Homo sapiens OX=9606 GN=CCDC30 PE=4 SV=1 4.37 2194.4 - 1.03E+07 - - - -0.1175 - 0.723 0.13 - 69.3 2 2 0 -0.0001 8 0 0 0 6.12E+07 1.45E+08 - - - -1.1115 0.9116 221125_WJC_METTL3_EV_vs_WT_F03.09716.09716.2 0.00036 18-Oct A.VQAAILSGDK[136.11].S "sp|P11142|HSP7C_HUMAN,tr|E9PNE6|E9PNE6_HUMAN,tr|A8K7Q2|A8K7Q2_HUMAN,tr|E9PKE3|E9PKE3_HUMAN" 4 1008.5695 0.4 26796 9716 2 1008.573133 505.292 Heat shock cognate 71 kDa protein OS=Homo sapiens OX=9606 GN=HSPA8 PE=1 SV=1 5.81 2194.5 - 2.29E+06 - - - 3.5922 - 1.781 0.441 - 300.5 1 1 0 0.0036 10 0 0 0 2.55E+07 6.33E+07 - - - 3.9082 0.9386 221125_WJC_METTL3_EV_vs_WT_F03.09717.09717.2 2.74 12-Sep L.LDGILDK[136.11].L "sp|Q9BXD5|NPL_HUMAN,sp|Q96A49|SYAP1_HUMAN,tr|A0A087WZ70|A0A087WZ70_HUMAN" 3 780.4473 1.38 26797 9717 2 780.445931 391.2309 N-acetylneuraminate lyase OS=Homo sapiens OX=9606 GN=NPL PE=1 SV=1 4.21 2194.6 - 1.58E+06 - - - -1.7157 - 1.895 0.238 - 213.2 1 1 0 -0.0013 7 0 0 0 3.04E+08 2.20E+08 - - - 2.8238 0.9997 221125_WJC_METTL3_EV_vs_WT_F03.09724.09724.2 0.00102 14-Aug K.TFTMEGER[166.11].S "sp|P52732|KIF11_HUMAN,tr|A0A7I2YQY4|A0A7I2YQY4_HUMAN,tr|A0A7I2V3A9|A0A7I2V3A9_HUMAN,tr|A0A7I2V3V3|A0A7I2V3V3_HUMAN" 4 979.4309 4.19 26802 9724 2 979.430233 490.7227 Kinesin-like protein KIF11 OS=Homo sapiens OX=9606 GN=KIF11 PE=1 SV=2 4.53 2195.4 - 2.13E+06 - - - -0.631 - 1.34 0.5 - 223.3 1 2 0 -0.0006 8 0 0 0 1.47E+09 3.51E+08 - - - 3.6165 0.8583 221125_WJC_METTL3_EV_vs_WT_F03.09725.09725.2 0.49 12-Aug L.LDGILDK.L "sp|Q9BXD5|NPL_HUMAN,sp|Q96A49|SYAP1_HUMAN,tr|A0A087WZ70|A0A087WZ70_HUMAN" 3 772.4331 1.38 26803 9725 2 772.432709 387.2238 N-acetylneuraminate lyase OS=Homo sapiens OX=9606 GN=NPL PE=1 SV=1 4.21 2195.4 - 3.09E+06 - - - -0.4674 - 1.618 0.135 - 177.6 1 1 0 -0.0004 7 0 0 0 3.04E+08 2.20E+08 - - - 1.5627 0.9929 221125_WJC_METTL3_EV_vs_WT_F03.09726.09726.2 0.000106 20-Oct F.LLTGAYDNTAK.L sp|O43172|PRP4_HUMAN 1 1165.5979 102.85 26804 9726 2 1165.59826 583.8062 U4\U6 small nuclear ribonucleoprotein Prp4 OS=Homo sapiens OX=9606 GN=PRPF4 PE=1 SV=2 5.83 2195.6 - 889839 - - - 0.3063 - 2.045 0.539 - 249.8 1 1 0 0.0004 11 0 0 0 3.95E+07 3.85E+05 - - - 4.9573 0.9998 221125_WJC_METTL3_EV_vs_WT_F03.09736.09736.2 0.000224 14/24 R.AALEAAAAAAPER[166.11].G sp|Q86UK7|ZN598_HUMAN 1 1220.6389 1.39 26809 9736 2 1220.640266 611.3267 E3 ubiquitin-protein ligase ZNF598 OS=Homo sapiens OX=9606 GN=ZNF598 PE=1 SV=1 4.53 2196.9 - 669798 - - - 1.1437 - 3.123 0.392 - 760.4 1 2 0 0.0014 13 0 0 0 2.93E+07 2.11E+07 - - - 4.8586 0.9958 221125_WJC_METTL3_EV_vs_WT_F03.09739.09739.2 0.0398 14-Jul R.VEVLPQAR[166.11].A sp|Q00587|BORG5_HUMAN 1 920.5319 1.99 26810 9739 2 920.528664 461.2732 Cdc42 effector protein 1 OS=Homo sapiens OX=9606 GN=CDC42EP1 PE=1 SV=1 5.97 2197.3 - 3.51E+06 - - - -3.5002 - 1.564 0.321 - 223.7 1 2 0 -0.0032 8 0 0 0 6.09E+08 3.05E+08 - - - 2.7598 0.9997 221125_WJC_METTL3_EV_vs_WT_F03.09742.09742.2 0.027 18-Oct K.FLNDSEQVAR.A "sp|Q9BVT8|TMUB1_HUMAN,tr|C9JE12|C9JE12_HUMAN,tr|A0A590UJA9|A0A590UJA9_HUMAN,tr|C9JCW7|C9JCW7_HUMAN" 4 1177.5728 1.36 26812 9742 2 1177.57087 589.7937 Transmembrane and ubiquitin-like domain-containing protein 1 OS=Homo sapiens OX=9606 GN=TMUB1 PE=1 SV=1 4.37 2197.6 - 479729 - - - -1.5974 - 1.852 0.455 - 301.4 1 2 0 -0.0019 10 0 0 0 4.17E+07 3.05E+07 - - - 4.1212 0.9971 221125_WJC_METTL3_EV_vs_WT_F03.09743.09743.2 0.000641 18-Oct K.FLNDSEQVAR[166.11].A "sp|Q9BVT8|TMUB1_HUMAN,tr|C9JE12|C9JE12_HUMAN,tr|A0A590UJA9|A0A590UJA9_HUMAN,tr|C9JCW7|C9JCW7_HUMAN" 4 1187.581 1.45 26813 9743 2 1187.575849 594.7978 Transmembrane and ubiquitin-like domain-containing protein 1 OS=Homo sapiens OX=9606 GN=TMUB1 PE=1 SV=1 4.37 2197.8 - 625796 - - - -4.3551 - 1.828 0.422 - 287.3 1 2 0 -0.0052 10 0 0 0 4.03E+07 2.78E+07 - - - 3.84 0.9992 221125_WJC_METTL3_EV_vs_WT_F03.09746.09746.2 0.000692 14-Jul K.TFTMEGER.S "sp|P52732|KIF11_HUMAN,tr|A0A7I2YQY4|A0A7I2YQY4_HUMAN,tr|A0A7I2V3A9|A0A7I2V3A9_HUMAN,tr|A0A7I2V3V3|A0A7I2V3V3_HUMAN" 4 969.4226 4.19 26814 9746 2 969.421403 485.7186 Kinesin-like protein KIF11 OS=Homo sapiens OX=9606 GN=KIF11 PE=1 SV=2 4.53 2198.2 - 3.52E+07 - - - -1.2152 - 1.167 0.445 - 167.3 1 2 0 -0.0012 8 0 0 0 1.47E+09 3.51E+08 - - - 2.7932 0.9998 221125_WJC_METTL3_EV_vs_WT_F03.09749.09749.2 4.91E-07 18-Oct K.EAVAMESYAK[136.11].A "sp|P78371|TCPB_HUMAN,tr|F5GWF6|F5GWF6_HUMAN" 2 1105.5205 0.46 26816 9749 2 1105.518785 553.7675 T-complex protein 1 subunit beta OS=Homo sapiens OX=9606 GN=CCT2 PE=1 SV=4 4.53 2198.4 - 2.12E+06 - - - -1.5613 - 2.032 0.475 - 482 1 2 0 -0.0017 10 0 0 0 7.82E+08 1.68E+09 - - - 4.5279 1 221125_WJC_METTL3_EV_vs_WT_F03.09751.09751.2 3.96E-06 20-Nov R.YLAEVAAGDDK.K "sp|P63104|1433Z_HUMAN,tr|H0YB80|H0YB80_HUMAN,tr|E7EX29|E7EX29_HUMAN,tr|B7Z2E6|B7Z2E6_HUMAN,tr|B0AZS6|B0AZS6_HUMAN" 5 1150.5506 1.05 26818 9751 2 1150.549753 576.2826 14-3-3 protein zeta\delta OS=Homo sapiens OX=9606 GN=YWHAZ PE=1 SV=1 4.03 2198.6 - 698073 - - - -0.7527 - 2.325 0.602 - 323.6 1 2 0 -0.0009 11 0 0 0 5.78E+07 5.51E+07 - - - 5.7696 0.9976 221125_WJC_METTL3_EV_vs_WT_F03.09756.09756.2 0.0571 16-Oct K.LQQTTQLIK[136.11].E sp|Q9NUQ3|TXLNG_HUMAN 1 1079.643 1.27 26821 9756 2 1079.641089 540.8288 Gamma-taxilin OS=Homo sapiens OX=9606 GN=TXLNG PE=1 SV=2 8.75 2199.3 - 1.65E+06 - - - -1.7784 - 1.786 0.194 - 220.5 1 2 0 -0.0019 9 0 0 0 6.71E+07 5.27E+07 - - - 2.1512 0.9997 221125_WJC_METTL3_EV_vs_WT_F03.09761.09761.2 0.0469 18-Oct K.VLLEEGEAQR[166.11].L "sp|P11441|UBL4A_HUMAN,tr|Q5HY81|Q5HY81_HUMAN" 2 1152.6014 1.69 26824 9761 2 1152.600437 577.308 Ubiquitin-like protein 4A OS=Homo sapiens OX=9606 GN=UBL4A PE=1 SV=1 4.25 2199.9 - 1.19E+06 - - - -0.8546 - 1.908 0.39 - 421.7 1 2 0 -0.001 10 0 0 0 2.11E+08 1.25E+08 - - - 3.7246 0.9992 221125_WJC_METTL3_EV_vs_WT_F03.09762.09762.2 0.055 22-Nov R.AVLIAGQPGTGK[136.11].T "sp|Q9Y230|RUVB2_HUMAN,tr|M0R0Y3|M0R0Y3_HUMAN,tr|M0QXI6|M0QXI6_HUMAN,tr|X6R2L4|X6R2L4_HUMAN" 4 1118.6539 0.97 26825 9762 2 1118.6526 560.3342 RuvB-like 2 OS=Homo sapiens OX=9606 GN=RUVBL2 PE=1 SV=3 8.8 2199.9 - 5.50E+06 - - - -1.1693 - 1.98 0.262 - 149.4 1 2 0 -0.0013 12 0 0 0 1.78E+08 1.83E+08 - - - 2.7731 0.9919 221125_WJC_METTL3_EV_vs_WT_F03.09764.09764.2 0.0897 16-May K.IILQPC[160.03]GSK.S "sp|Q15517|CDSN_HUMAN,tr|G8JLG2|G8JLG2_HUMAN,tr|Q2L6G8|Q2L6G8_HUMAN" 3 1014.5532 115.9 26827 9764 2 1014.552938 508.2839 Corneodesmosin OS=Homo sapiens OX=9606 GN=CDSN PE=1 SV=3 8.22 2200 - 1.57E+06 - - - -0.2602 - 1.155 0.176 - 62.8 1 2 0 -0.0003 9 0 0 0 4.15E+08 3.58E+06 - - - 0.7577 0.9956 221125_WJC_METTL3_EV_vs_WT_F03.09768.09768.2 0.968 12-Jun R.QTASIFK.Q "sp|Q9UBB5|MBD2_HUMAN,sp|O95983|MBD3_HUMAN,tr|A0A087X1H1|A0A087X1H1_HUMAN,tr|K7EIE8|K7EIE8_HUMAN,tr|A0A087WT34|A0A087WT34_HUMAN,tr|A0A0A0MTS6|A0A0A0MTS6_HUMAN,tr|J3KSA7|J3KSA7_HUMAN" 7 793.4334 1.5 26829 9768 2 793.433001 397.724 Methyl-CpG-binding domain protein 2 OS=Homo sapiens OX=9606 GN=MBD2 PE=1 SV=1 8.75 2200.5 - 2.31E+06 - - - -0.5079 - 1.198 0.216 - 168.1 1 2 0 -0.0004 7 0 0 0 7.57E+08 5.03E+08 - - - 1.2087 0.9999 221125_WJC_METTL3_EV_vs_WT_F03.09769.09769.2 0.000216 18-Oct K.VLLEEGEAQR.L "sp|P11441|UBL4A_HUMAN,tr|Q5HY81|Q5HY81_HUMAN" 2 1142.5932 1.68 26830 9769 2 1142.593761 572.3039 Ubiquitin-like protein 4A OS=Homo sapiens OX=9606 GN=UBL4A PE=1 SV=1 4.25 2200.6 - 2.10E+06 - - - 0.533 - 2.18 0.472 - 415.7 1 2 0 0.0006 10 0 0 0 2.15E+08 1.27E+08 - - - 4.7023 0.9995 221125_WJC_METTL3_EV_vs_WT_F03.09770.09770.2 6.24E-05 20-Nov R.YLAEVAAGDDK[136.11].K "sp|P63104|1433Z_HUMAN,tr|H0YB80|H0YB80_HUMAN,tr|E7EX29|E7EX29_HUMAN,tr|B7Z2E6|B7Z2E6_HUMAN,tr|B0AZS6|B0AZS6_HUMAN" 5 1158.5648 1.2 26831 9770 2 1158.562512 580.2897 14-3-3 protein zeta\delta OS=Homo sapiens OX=9606 GN=YWHAZ PE=1 SV=1 4.03 2200.7 - 1.20E+06 - - - -1.9913 - 2.144 0.389 - 309.7 1 2 0 -0.0023 11 0 0 0 7.08E+07 5.91E+07 - - - 3.9766 0.9999 221125_WJC_METTL3_EV_vs_WT_F03.09774.09774.2 2.55E-05 18-Oct K.EAVAMESYAK.A "sp|P78371|TCPB_HUMAN,tr|F5GWF6|F5GWF6_HUMAN" 2 1097.5063 0.46 26833 9774 2 1097.505697 549.7604 T-complex protein 1 subunit beta OS=Homo sapiens OX=9606 GN=CCT2 PE=1 SV=4 4.53 2201.2 - 6.68E+06 - - - -0.5595 - 1.891 0.524 - 278 1 2 0 -0.0006 10 0 0 0 7.82E+08 1.68E+09 - - - 4.6894 0.9995 221125_WJC_METTL3_EV_vs_WT_F03.09775.09775.2 0.000928 18-Sep R.IMGPNYTPGK[136.11].K sp|P13639|EF2_HUMAN 1 1084.5467 0.4 26834 9775 2 1084.545475 543.2806 Elongation factor 2 OS=Homo sapiens OX=9606 GN=EEF2 PE=1 SV=4 8.59 2201.2 - 2.59E+06 - - - -1.0982 - 1.375 0.465 - 190.7 1 2 0 -0.0012 10 0 0 0 3.56E+07 8.82E+07 - - - 3.364 0.9505 221125_WJC_METTL3_EV_vs_WT_F03.09776.09776.2 2.1 12-Jul K.LYTLQDK[136.11].A "sp|P49327|FAS_HUMAN,tr|A0A0U1RQF0|A0A0U1RQF0_HUMAN" 2 887.4844 0.59 26835 9776 2 887.486008 444.7495 Fatty acid synthase OS=Homo sapiens OX=9606 GN=FASN PE=1 SV=3 5.83 2201.3 - 1.96E+06 - - - 1.831 - 1.208 0.071 - 112.2 2 2 0 0.0016 7 0 0 0 6.13E+07 1.03E+08 - - - 0.0292 0.9443 221125_WJC_METTL3_EV_vs_WT_F03.09777.09777.2 2.88 16-May K.GSSASLVLK.R sp|Q00325|MPCP_HUMAN 1 860.4967 1.04 26836 9777 2 860.49601 431.2556 "Phosphate carrier protein, mitochondrial OS=Homo sapiens OX=9606 GN=SLC25A3 PE=1 SV=2" 8.75 2201.3 - 1.67E+06 - - - -0.8402 - 1.239 0.063 - 49.3 18 2 0 -0.0007 9 0 0 0 9.05E+07 8.67E+07 - - - -0.4346 0.9966 221125_WJC_METTL3_EV_vs_WT_F03.09781.09781.2 0.0201 16-Jul K.GSSASLVLK[136.11].R sp|Q00325|MPCP_HUMAN 1 868.5109 1.04 26838 9781 2 868.508565 435.2627 "Phosphate carrier protein, mitochondrial OS=Homo sapiens OX=9606 GN=SLC25A3 PE=1 SV=2" 8.75 2201.8 - 2.52E+06 - - - -2.7265 - 1.425 0.319 - 166.2 1 2 0 -0.0024 9 0 0 0 8.94E+07 8.59E+07 - - - 2.421 0.9996 221125_WJC_METTL3_EV_vs_WT_F03.09782.09782.2 0.0749 20-Oct K.VGVQPAVC[160.03]VEK[136.11].K sp|Q96T17|MA7D2_HUMAN 1 1192.6365 0.29 26839 9782 2 1192.636672 597.3255 MAP7 domain-containing protein 2 OS=Homo sapiens OX=9606 GN=MAP7D2 PE=1 SV=2 5.97 2201.9 - 468247 - - - 0.1073 - 2.065 0.294 - 408.8 1 2 0 0.0001 11 0 0 0 3.75E+06 1.30E+07 - - - 3.1741 0.9951 221125_WJC_METTL3_EV_vs_WT_F03.09783.09783.2 0.0203 12-May K.WGDPVTR[166.11].V "sp|P46459|NSF_HUMAN,tr|I3L0N3|I3L0N3_HUMAN" 2 839.4165 1.26 26840 9783 2 839.416677 420.7155 Vesicle-fusing ATPase OS=Homo sapiens OX=9606 GN=NSF PE=1 SV=3 5.84 2202 - 1.15E+06 - - - 0.1847 - 1.122 0.233 - 77.2 1 2 0 0.0002 7 0 0 0 7.47E+07 5.94E+07 - - - 1.1266 0.9997 221125_WJC_METTL3_EV_vs_WT_F03.09784.09784.2 9.41E-06 18-Oct R.AGFTAAYSEK.G sp|P11717|MPRI_HUMAN 1 1043.4924 0.04 26841 9784 2 1043.490785 522.7535 Cation-independent mannose-6-phosphate receptor OS=Homo sapiens OX=9606 GN=IGF2R PE=1 SV=3 6.05 2202.1 - 648442 - - - -1.5237 - 1.77 0.473 - 271.5 1 2 0 -0.0016 10 0 0 0 1.90E+07 5.05E+08 - - - 4.1279 0.9966 221125_WJC_METTL3_EV_vs_WT_F03.09788.09788.2 0.222 16-Jun R.VPPPPPIAR.A "sp|P07910|HNRPC_HUMAN,tr|B4DY08|B4DY08_HUMAN,tr|G3V575|G3V575_HUMAN,tr|G3V5V7|G3V5V7_HUMAN,tr|B2R5W2|B2R5W2_HUMAN,tr|G3V4C1|G3V4C1_HUMAN,tr|G3V576|G3V576_HUMAN,tr|G3V2D6|G3V2D6_HUMAN,tr|G3V4W0|G3V4W0_HUMAN,tr|G3V555|G3V555_HUMAN,tr|G3V2Q1|G3V2Q1_HUMAN" 11 942.5651 1.67 26843 9788 2 942.565858 472.2898 Heterogeneous nuclear ribonucleoproteins C1\C2 OS=Homo sapiens OX=9606 GN=HNRNPC PE=1 SV=4 9.72 2202.6 - 6.73E+06 - - - 0.818 - 1.172 0.275 - 132 1 2 0 0.0008 9 0 0 0 4.84E+08 2.89E+08 - - - 1.5311 0.991 221125_WJC_METTL3_EV_vs_WT_F03.09789.09789.2 0.206 12-Jun R.SVVSFDK.V sp|Q15424|SAFB1_HUMAN 1 780.4018 1.38 26844 9789 2 780.400655 391.2082 Scaffold attachment factor B1 OS=Homo sapiens OX=9606 GN=SAFB PE=1 SV=4 5.55 2202.7 - 5.24E+06 - - - -1.4288 - 1.103 0.218 - 103.3 1 2 0 -0.0011 7 0 0 0 1.83E+08 1.33E+08 - - - 0.9614 0.9998 221125_WJC_METTL3_EV_vs_WT_F03.09793.09793.2 1.70E-07 14/20 R.YLAEVATGDDK.K sp|P31947|1433S_HUMAN 1 1180.5612 4.21 26846 9793 2 1180.559622 591.2879 14-3-3 protein sigma OS=Homo sapiens OX=9606 GN=SFN PE=1 SV=1 4.03 2203.2 - 1.31E+06 - - - -1.3223 - 2.629 0.462 - 585.5 1 2 0 -0.0016 11 0 0 0 9.61E+07 2.28E+07 - - - 5.0677 0.9955 221125_WJC_METTL3_EV_vs_WT_F03.09795.09795.2 0.17 16-Jul R.IISQVVDPK[136.11].L "sp|Q96IK1|BOD1_HUMAN,sp|Q8NFC6|BD1L1_HUMAN,tr|H7C5I4|H7C5I4_HUMAN,tr|C9J8U9|C9J8U9_HUMAN" 4 1005.595 1.61 26848 9795 2 1005.594051 503.8048 Biorientation of chromosomes in cell division protein 1 OS=Homo sapiens OX=9606 GN=BOD1 PE=1 SV=2 5.84 2203.4 - 809550 - - - -0.9407 - 1.103 0.266 - 121.5 1 2 0 -0.0009 9 0 0 0 7.37E+07 4.57E+07 - - - 1.289 0.9342 221125_WJC_METTL3_EV_vs_WT_F03.09796.09796.2 2.09 14-Jun K.ANLENPIR.L "sp|O00330|ODPX_HUMAN,tr|H0YD97|H0YD97_HUMAN" 2 925.4981 5.47 26849 9796 2 925.496537 463.7563 "Pyruvate dehydrogenase protein X component, mitochondrial OS=Homo sapiens OX=9606 GN=PDHX PE=1 SV=3" 6.05 2203.4 - 1.34E+06 - - - -1.7212 - 1.196 0.022 - 75.2 1 2 0 -0.0016 8 0 0 0 4.70E+07 8.60E+06 - - - -0.2572 0.994 221125_WJC_METTL3_EV_vs_WT_F03.09804.09804.2 0.121 16-Aug R.FGSGMNMGR.L "sp|P52272|HNRPM_HUMAN,tr|M0R019|M0R019_HUMAN,tr|M0QYL3|M0QYL3_HUMAN,tr|A0A087X0X3|A0A087X0X3_HUMAN,tr|M0QZM1|M0QZM1_HUMAN" 5 955.4004 1.5 26851 9804 2 955.4008 478.7075 Heterogeneous nuclear ribonucleoprotein M OS=Homo sapiens OX=9606 GN=HNRNPM PE=1 SV=3 9.75 2204.6 - 7.68E+06 - - - 0.4124 - 0.832 0.34 - 116.9 1 2 0 0.0004 9 0 0 0 8.25E+08 5.50E+08 - - - 1.02 0.9886 221125_WJC_METTL3_EV_vs_WT_F03.09808.09808.2 0.107 14-Jun K.VLSISTER.H "sp|Q7Z589|EMSY_HUMAN,tr|E9PMC9|E9PMC9_HUMAN" 2 903.5025 1.58 26852 9808 2 903.502027 452.7585 BRCA2-interacting transcriptional repressor EMSY OS=Homo sapiens OX=9606 GN=EMSY PE=1 SV=2 5.97 2205.1 - 1.53E+06 - - - -0.5744 - 1.308 0.096 - 105.1 1 2 0 -0.0005 8 0 0 0 7.25E+07 4.60E+07 - - - 0.5597 0.9978 221125_WJC_METTL3_EV_vs_WT_F03.09809.09809.2 0.291 14-Jul K.INFVGGNK.L sp|Q96KR1|ZFR_HUMAN 1 847.4552 1.38 26853 9809 2 847.455387 424.7349 Zinc finger RNA-binding protein OS=Homo sapiens OX=9606 GN=ZFR PE=1 SV=2 8.75 2205.2 - 872881 - - - 0.2183 - 1.358 0.238 - 122.6 1 2 0 0.0002 8 0 0 0 1.37E+08 9.89E+07 - - - 1.7217 0.9998 221125_WJC_METTL3_EV_vs_WT_F03.09811.09811.2 0.000118 18-Oct K.MALVADEQQR[166.11].L sp|Q99856|ARI3A_HUMAN 1 1169.5738 5.89 26855 9811 2 1169.575333 585.7942 AT-rich interactive domain-containing protein 3A OS=Homo sapiens OX=9606 GN=ARID3A PE=1 SV=2 4.37 2205.4 - 334476 - - - 1.2876 - 2.099 0.476 - 443.9 1 2 0 0.0015 10 0 0 0 6.29E+07 1.07E+07 - - - 4.6259 0.7811 221125_WJC_METTL3_EV_vs_WT_F03.09812.09812.2 3.07 18-Jun K.LATEYMSSAR[166.11].S sp|Q9UNL4|ING4_HUMAN 1 1137.5364 0.22 26856 9812 2 1137.538823 569.7755 Inhibitor of growth protein 4 OS=Homo sapiens OX=9606 GN=ING4 PE=1 SV=1 6 2205.5 - 220738 - - - 2.1485 - 0.999 0.01 - 91.3 1 2 0 0.0024 10 0 0 0 1.33E+06 6.10E+06 - - - -0.8887 0.9957 221125_WJC_METTL3_EV_vs_WT_F03.09818.09818.2 0.0496 12-Jun K.WGDPVTR.V "sp|P46459|NSF_HUMAN,tr|I3L0N3|I3L0N3_HUMAN" 2 829.4083 1.29 26859 9818 2 829.408173 415.7114 Vesicle-fusing ATPase OS=Homo sapiens OX=9606 GN=NSF PE=1 SV=3 5.84 2206.2 - 1.97E+06 - - - -0.0952 - 1.081 0.259 - 173.6 1 2 0 -0.0001 7 0 0 0 7.69E+07 5.97E+07 - - - 1.2007 0.9977 221125_WJC_METTL3_EV_vs_WT_F03.09827.09827.2 0.0445 12-Jun R.AYEFAER[166.11].C "sp|Q00610|CLH1_HUMAN,sp|P53675|CLH2_HUMAN,tr|A0A087WVQ6|A0A087WVQ6_HUMAN,tr|A0A087WX41|A0A087WX41_HUMAN" 4 894.4111 1.44 26865 9827 2 894.411139 448.2128 Clathrin heavy chain 1 OS=Homo sapiens OX=9606 GN=CLTC PE=1 SV=5 4.53 2207.2 - 1.38E+06 - - - 0.0414 - 1.188 0.283 - 152.9 1 2 0 0 7 0 0 0 2.17E+08 1.50E+08 - - - 1.6771 0.9964 221125_WJC_METTL3_EV_vs_WT_F03.09828.09828.2 0.24 14-Aug R.LTVDEAVR.A "sp|Q15149|PLEC_HUMAN,sp|Q15149|PLEC_HUMAN,tr|H0YDN1|H0YDN1_HUMAN,tr|H0YDN1|H0YDN1_HUMAN" 4 901.4869 2.12 26866 9828 2 901.484609 451.7507 Plectin OS=Homo sapiens OX=9606 GN=PLEC PE=1 SV=3 4.37 2207.2 - 1.44E+06 - - - -2.5369 - 1.763 0.204 - 201.7 1 2 0 -0.0023 8 0 0 0 1.03E+08 4.85E+07 - - - 2.2571 0.9998 221125_WJC_METTL3_EV_vs_WT_F03.09829.09829.2 0.000102 18-Oct K.LLDVVHPAAK[136.11].T "sp|Q99832|TCPH_HUMAN,tr|F8WAM2|F8WAM2_HUMAN" 2 1069.6375 0.15 26867 9829 2 1069.638335 535.826 T-complex protein 1 subunit eta OS=Homo sapiens OX=9606 GN=CCT7 PE=1 SV=2 6.74 2207.3 - 887849 - - - 0.7526 - 1.99 0.468 - 276.5 1 2 0 0.0008 10 0 0 0 7.69E+07 5.01E+08 - - - 4.4182 0.9973 221125_WJC_METTL3_EV_vs_WT_F03.09835.09835.2 0.02 12-Jun K.FFTTPSK.S sp|O76021|RL1D1_HUMAN 1 826.4225 0.81 26871 9835 2 826.422898 414.2185 Ribosomal L1 domain-containing protein 1 OS=Homo sapiens OX=9606 GN=RSL1D1 PE=1 SV=3 8.75 2208.1 - 2.10E+06 - - - 0.4755 - 1.136 0.296 - 99.8 1 2 0 0.0004 7 0 0 0 8.91E+07 1.10E+08 - - - 1.6312 0.8513 221125_WJC_METTL3_EV_vs_WT_F03.09836.09836.2 0.183 12-May R.DVNC[160.03]PFK[136.11].L "sp|Q9Y224|RTRAF_HUMAN,tr|G3V4C6|G3V4C6_HUMAN,tr|H0YJB9|H0YJB9_HUMAN" 3 886.4098 0.97 26872 9836 2 886.410096 444.2122 "RNA transcription, translation and transport factor protein OS=Homo sapiens OX=9606 GN=RTRAF PE=1 SV=1" 5.83 2208.1 - 1.71E+06 - - - 0.2899 - 0.895 0.05 - 69.9 3 2 0 0.0003 7 0 0 0 9.79E+07 1.01E+08 - - - -1.1544 0.9975 221125_WJC_METTL3_EV_vs_WT_F03.09837.09837.2 0.0263 12-Jun R.DVNC[160.03]PFK.L "sp|Q9Y224|RTRAF_HUMAN,tr|G3V4C6|G3V4C6_HUMAN,tr|H0YJB9|H0YJB9_HUMAN" 3 878.3956 0.83 26873 9837 2 878.395366 440.2051 "RNA transcription, translation and transport factor protein OS=Homo sapiens OX=9606 GN=RTRAF PE=1 SV=1" 5.83 2208.1 - 1.69E+06 - - - -0.3108 - 1.023 0.338 - 133.6 1 2 0 -0.0003 7 0 0 0 9.96E+07 1.20E+08 - - - 1.6094 0.7669 221125_WJC_METTL3_EV_vs_WT_F03.09840.09840.2 0.523 12-Jun L.DHYAIIK[136.11].F "sp|P62750|RL23A_HUMAN,tr|H7BY10|H7BY10_HUMAN,tr|K7ERT8|K7ERT8_HUMAN,tr|A8MUS3|A8MUS3_HUMAN,tr|K7EJV9|K7EJV9_HUMAN" 5 866.4742 1.34 26874 9840 2 866.475527 434.2444 60S ribosomal protein L23a OS=Homo sapiens OX=9606 GN=RPL23A PE=1 SV=1 6.74 2208.5 - 2.23E+06 - - - 1.5857 - 1.383 0.198 - 139.2 1 1 0 0.0014 7 0 0 0 9.23E+07 6.90E+07 - - - 1.5304 1 221125_WJC_METTL3_EV_vs_WT_F03.09845.09845.2 1.16E-06 16-Oct R.YDDMAAC[160.03]MK[136.11].S "sp|P63104|1433Z_HUMAN,tr|E7EX29|E7EX29_HUMAN,tr|E5RIR4|E5RIR4_HUMAN,tr|E7EVZ2|E7EVZ2_HUMAN,tr|E5RGE1|E5RGE1_HUMAN,tr|E9PD24|E9PD24_HUMAN,tr|E7ESK7|E7ESK7_HUMAN" 7 1111.4228 1.07 26877 9845 2 1111.423544 556.7187 14-3-3 protein zeta\delta OS=Homo sapiens OX=9606 GN=YWHAZ PE=1 SV=1 4.21 2209.1 - 611604 - - - 0.6802 - 2.029 0.662 - 290.8 1 2 0 0.0008 9 0 0 0 1.92E+07 1.80E+07 - - - 5.9773 0.8966 221125_WJC_METTL3_EV_vs_WT_F03.09847.09847.2 0.0206 18-May R.LLVEEGC[160.03]EDR.L "sp|Q96BW5|PTER_HUMAN,tr|A0A0A0MSI3|A0A0A0MSI3_HUMAN" 2 1218.5551 1.18 26879 9847 2 1218.566121 610.2848 Phosphotriesterase-related protein OS=Homo sapiens OX=9606 GN=PTER PE=1 SV=1 4 2209.3 - 130223 - - - 9.0837 - 1.224 0.389 - 44.5 1 2 0 0.0111 10 0 0 0 1.98E+06 1.68E+06 - - - 2.4749 0.9978 221125_WJC_METTL3_EV_vs_WT_F03.09850.09850.2 0.421 14-Jul R.LTPEELER[166.11].A "sp|O95399|UTS2_HUMAN,sp|P11021|BIP_HUMAN,tr|A0A7P0TB36|A0A7P0TB36_HUMAN,tr|A0A7P0TAI0|A0A7P0TAI0_HUMAN,tr|Q5H8X8|Q5H8X8_HUMAN" 5 995.5163 0.63 26880 9850 2 995.516501 498.7654 Urotensin-2 OS=Homo sapiens OX=9606 GN=UTS2 PE=1 SV=1 4.25 2209.7 - 2.91E+06 - - - 0.2059 - 1.431 0.218 - 239.9 1 2 0 0.0002 8 0 0 0 5.85E+08 9.25E+08 - - - 1.7319 0.9955 221125_WJC_METTL3_EV_vs_WT_F03.09852.09852.2 0.205 12-Jul R.FSGVPDR.F "sp|A0A075B6R9|KVD24_HUMAN,sp|A0A0C4DH68|KV224_HUMAN,sp|A2NJV5|KV229_HUMAN,sp|A0A075B6S2|KVD29_HUMAN,sp|A0A0A0MRZ7|KVD26_HUMAN" 5 776.3817 3.84 26882 9852 2 776.382191 389.1981 Probable non-functional immunoglobulin kappa variable 2D-24 OS=Homo sapiens OX=9606 GN=IGKV2D-24 PE=1 SV=1 5.84 2209.9 - 1.53E+06 - - - 0.6286 - 1.263 0.201 - 141.6 1 2 0 0.0005 7 0 0 0 6.41E+08 1.67E+08 - - - 1.2653 0.9962 221125_WJC_METTL3_EV_vs_WT_F03.09855.09855.2 0.0772 12-Jun K.SSFSITR.E "sp|Q9Y2W1|TR150_HUMAN,tr|A0A3B3ITZ9|A0A3B3ITZ9_HUMAN" 2 796.4079 2.41 26883 9855 2 796.408331 399.2112 Thyroid hormone receptor-associated protein 3 OS=Homo sapiens OX=9606 GN=THRAP3 PE=1 SV=2 9.47 2210.4 - 2.82E+07 - - - 0.5186 - 1.293 0.205 - 164.1 1 2 0 0.0004 7 0 0 0 2.85E+10 1.18E+10 - - - 1.3692 0.9792 221125_WJC_METTL3_EV_vs_WT_F03.09856.09856.2 0.00138 16-Oct L.LDVVHPAAK[136.11].T "sp|Q99832|TCPH_HUMAN,tr|F8WAM2|F8WAM2_HUMAN" 2 956.5535 4.75 26884 9856 2 956.553761 479.284 T-complex protein 1 subunit eta OS=Homo sapiens OX=9606 GN=CCT7 PE=1 SV=2 6.74 2210.4 - 2.17E+06 - - - 0.3084 - 1.774 0.37 - 226 1 1 0 0.0003 9 0 0 0 1.35E+09 2.84E+08 - - - 3.4321 0.9993 221125_WJC_METTL3_EV_vs_WT_F03.09858.09858.2 0.00684 20-Nov K.IAGGTSLEVAR[166.11].F sp|Q9H6T0|ESRP2_HUMAN 1 1082.5959 1.14 26886 9858 2 1082.596811 542.3052 Epithelial splicing regulatory protein 2 OS=Homo sapiens OX=9606 GN=ESRP2 PE=1 SV=1 6 2210.5 - 1.14E+06 - - - 0.8018 - 2.197 0.236 - 309.1 1 2 0 0.0009 11 0 0 0 5.58E+07 4.91E+07 - - - 2.9131 0.9991 221125_WJC_METTL3_EV_vs_WT_F03.09865.09865.2 0.0162 12-Jun R.AYEFAER.C "sp|Q00610|CLH1_HUMAN,sp|P53675|CLH2_HUMAN,tr|A0A087WVQ6|A0A087WVQ6_HUMAN,tr|A0A087WX41|A0A087WX41_HUMAN" 4 884.4028 1.31 26891 9865 2 884.403281 443.2087 Clathrin heavy chain 1 OS=Homo sapiens OX=9606 GN=CLTC PE=1 SV=5 4.53 2211.4 - 5.29E+06 - - - 0.5077 - 1.211 0.392 - 133.8 1 2 0 0.0004 7 0 0 0 2.22E+08 1.69E+08 - - - 2.5428 0.996 221125_WJC_METTL3_EV_vs_WT_F03.09869.09869.2 0.125 12-Jul K.YIQDFQR.E "sp|P17480|UBF1_HUMAN,tr|E9PMM2|E9PMM2_HUMAN,tr|E9PKP7|E9PKP7_HUMAN" 3 968.4716 0.44 26894 9869 2 968.471396 485.2431 Nucleolar transcription factor 1 OS=Homo sapiens OX=9606 GN=UBTF PE=1 SV=1 5.84 2211.8 - 3.89E+06 - - - -0.19 - 1.134 0.246 - 126.5 1 2 0 -0.0002 7 0 0 0 9.08E+07 2.08E+08 - - - 1.2563 0.9986 221125_WJC_METTL3_EV_vs_WT_F03.09872.09872.2 0.126 16-Jun K.ETAEAYLGK.K "sp|P11021|BIP_HUMAN,tr|A0A7P0TB36|A0A7P0TB36_HUMAN,tr|A0A7P0TAI0|A0A7P0TAI0_HUMAN" 3 980.4815 0.69 26895 9872 2 980.481315 491.248 Endoplasmic reticulum chaperone BiP OS=Homo sapiens OX=9606 GN=HSPA5 PE=1 SV=2 4.53 2212.2 - 2.72E+06 - - - -0.1642 - 1.369 0.288 - 112.7 1 2 0 -0.0002 9 0 0 0 1.52E+08 2.22E+08 - - - 2.0768 0.9728 221125_WJC_METTL3_EV_vs_WT_F03.09873.09873.2 7.88 12-Jul R.ELEIEER[166.11].E sp|Q14152|EIF3A_HUMAN 1 926.4584 1.51 26896 9873 2 926.458163 464.2365 Eukaryotic translation initiation factor 3 subunit A OS=Homo sapiens OX=9606 GN=EIF3A PE=1 SV=1 4.09 2212.2 - 1.22E+06 - - - -0.3055 - 1.367 0.008 - 187.7 2 2 0 -0.0003 7 0 0 0 1.29E+08 8.54E+07 - - - -0.0439 0.9972 221125_WJC_METTL3_EV_vs_WT_F03.09874.09874.2 0.0571 14-Jul K.LTTEEVIK[136.11].E sp|O15355|PPM1G_HUMAN 1 939.5368 0.72 26897 9874 2 939.536923 470.7757 Protein phosphatase 1G OS=Homo sapiens OX=9606 GN=PPM1G PE=1 SV=1 4.53 2212.3 - 2.49E+06 - - - 0.1171 - 1.445 0.206 - 127.2 2 2 0 0.0001 8 0 0 0 8.39E+07 1.17E+08 - - - 1.5382 0.9525 221125_WJC_METTL3_EV_vs_WT_F03.09875.09875.2 0.198 12-Jul K.AAC[160.03]LLPK.L "sp|P02768|ALBU_HUMAN,tr|B7WNR0|B7WNR0_HUMAN,tr|H0YA55|H0YA55_HUMAN,tr|A0A0C4DGB6|A0A0C4DGB6_HUMAN,tr|D6RHD5|D6RHD5_HUMAN" 5 771.4313 11.76 26898 9875 2 771.427652 386.7229 Albumin OS=Homo sapiens OX=9606 GN=ALB PE=1 SV=2 8.27 2212.4 - 673260 - - - -4.7237 - 1.436 0.17 - 190.8 1 2 0 -0.0036 7 0 0 0 4.76E+07 4.05E+06 - - - 1.4421 0.9951 221125_WJC_METTL3_EV_vs_WT_F03.09880.09880.2 0.0624 20-Jul K.GTLQAGPALGR[166.11].R sp|O94761|RECQ4_HUMAN 1 1049.5857 3.34 26901 9880 2 1049.586055 525.8001 ATP-dependent DNA helicase Q4 OS=Homo sapiens OX=9606 GN=RECQL4 PE=1 SV=2 9.75 2213 - 917417 - - - 0.3258 - 1.526 0.16 - 109.2 3 2 0 0.0003 11 0 0 0 1.21E+08 3.64E+07 - - - 1.1529 0.9932 221125_WJC_METTL3_EV_vs_WT_F03.09885.09885.2 0.0811 12-Jun K.SSFSITR[166.11].E "sp|Q9Y2W1|TR150_HUMAN,tr|A0A3B3ITZ9|A0A3B3ITZ9_HUMAN" 2 806.4162 2.41 26904 9885 2 806.414562 404.2154 Thyroid hormone receptor-associated protein 3 OS=Homo sapiens OX=9606 GN=THRAP3 PE=1 SV=2 9.47 2213.7 - 2.06E+08 - - - -2.0163 - 1.296 0.215 - 174.8 1 2 0 -0.0016 7 0 0 0 2.85E+10 1.18E+10 - - - 1.45 0.9975 221125_WJC_METTL3_EV_vs_WT_F03.09886.09886.2 0.0602 12-Aug K.NIQVVVR.C "sp|P52732|KIF11_HUMAN,tr|A0A7I2YQY4|A0A7I2YQY4_HUMAN,tr|A0A7I2V3V3|A0A7I2V3V3_HUMAN" 3 826.5025 4.23 26905 9886 2 826.501587 414.2585 Kinesin-like protein KIF11 OS=Homo sapiens OX=9606 GN=KIF11 PE=1 SV=2 9.75 2213.7 - 3.40E+06 - - - -1.0889 - 1.389 0.23 - 275.5 1 2 0 -0.0009 7 0 0 0 2.33E+09 5.51E+08 - - - 1.7806 0.9404 221125_WJC_METTL3_EV_vs_WT_F03.09887.09887.2 2.06 12-Jul R.ELEIEER.E sp|Q14152|EIF3A_HUMAN 1 916.4502 1.5 26906 9887 2 916.446767 459.2324 Eukaryotic translation initiation factor 3 subunit A OS=Homo sapiens OX=9606 GN=EIF3A PE=1 SV=1 4.09 2213.8 - 2.18E+06 - - - -3.7198 - 1.541 0.046 - 259.1 1 2 0 -0.0034 7 0 0 0 1.29E+08 8.62E+07 - - - 0.7499 0.9903 221125_WJC_METTL3_EV_vs_WT_F03.09892.09892.2 0.0703 18-Jul K.EPGTVALVSK[136.11].V sp|Q9HAV7|GRPE1_HUMAN 1 1007.5743 1.14 26909 9892 2 1007.5716 504.7944 "GrpE protein homolog 1, mitochondrial OS=Homo sapiens OX=9606 GN=GRPEL1 PE=1 SV=2" 6.1 2214.3 - 1.19E+06 - - - -2.641 - 1.379 0.214 - 170.4 1 2 0 -0.0027 10 0 0 0 7.78E+07 6.83E+07 - - - 1.5178 0.9982 221125_WJC_METTL3_EV_vs_WT_F03.09896.09896.2 0.0132 14-Aug R.QQVEALYR.L sp|Q9Y399|RT02_HUMAN 1 1005.5243 0.65 26912 9896 2 1005.524675 503.7694 "28S ribosomal protein S2, mitochondrial OS=Homo sapiens OX=9606 GN=MRPS2 PE=1 SV=1" 6 2214.7 - 1.31E+06 - - - 0.3292 - 1.496 0.226 - 295 1 2 0 0.0003 8 0 0 0 4.31E+07 6.64E+07 - - - 1.9249 0.9991 221125_WJC_METTL3_EV_vs_WT_F03.09900.09900.2 0.37 16-Dec R.VAVVNQIAR[166.11].Q "sp|Q01082|SPTB2_HUMAN,tr|A0A087WUZ3|A0A087WUZ3_HUMAN" 2 978.585 1.85 26914 9900 2 978.583437 490.2998 "Spectrin beta chain, non-erythrocytic 1 OS=Homo sapiens OX=9606 GN=SPTBN1 PE=1 SV=2" 9.72 2215.1 - 6.39E+06 - - - -1.5809 - 2.188 0.221 - 631.8 1 2 0 -0.0015 9 0 0 0 2.16E+08 1.17E+08 - - - 2.938 0.9957 221125_WJC_METTL3_EV_vs_WT_F03.09904.09904.2 0.341 14-Aug R.STVAQLVK.R "sp|P25705|ATPA_HUMAN,tr|K7ENJ4|K7ENJ4_HUMAN" 2 844.5018 1.29 26917 9904 2 844.500065 423.2582 "ATP synthase subunit alpha, mitochondrial OS=Homo sapiens OX=9606 GN=ATP5F1A PE=1 SV=1" 8.47 2215.6 - 2.50E+07 - - - -2.0758 - 1.363 0.252 - 252.1 1 2 0 -0.0018 8 0 0 0 6.22E+08 4.83E+08 - - - 1.8357 0.9912 221125_WJC_METTL3_EV_vs_WT_F03.09913.09913.2 0.0404 16-Oct R.LGAPALTSR[166.11].Q "sp|P34897|GLYM_HUMAN,tr|H0YIZ0|H0YIZ0_HUMAN" 2 894.5162 2.61 26921 9913 2 894.519274 448.2654 "Serine hydroxymethyltransferase, mitochondrial OS=Homo sapiens OX=9606 GN=SHMT2 PE=1 SV=3" 9.75 2216.7 - 1.49E+06 - - - 3.3962 - 1.636 0.215 - 218.7 1 2 0 0.003 9 0 0 0 1.24E+08 4.74E+07 - - - 2.0522 0.9377 221125_WJC_METTL3_EV_vs_WT_F03.09914.09914.2 3.28 12-May K.FLQYESK[136.11].K "sp|Q00537|CDK17_HUMAN,tr|F5H6Z0|F5H6Z0_HUMAN" 2 921.4687 2.39 26922 9914 2 921.46728 461.7416 Cyclin-dependent kinase 17 OS=Homo sapiens OX=9606 GN=CDK17 PE=1 SV=2 6 2216.8 - 973059 - - - -1.5768 - 1.178 0.04 - 54.3 2 2 0 -0.0015 7 0 0 0 1.32E+08 5.52E+07 - - - -0.2794 0.7691 221125_WJC_METTL3_EV_vs_WT_F03.09920.09920.2 2.42 14-May R.SAQSSEGR.- tr|J3QR08|J3QR08_HUMAN 1 820.3675 1.99 26925 9920 2 820.36536 411.191 Retinoic acid-induced protein 1 (Fragment) OS=Homo sapiens OX=9606 GN=RAI1 PE=1 SV=1 5.72 2217.6 - 1.38E+06 - - - -2.6196 - 0.805 0.134 - 72.6 2 2 0 -0.0022 8 0 0 0 2.20E+07 1.10E+07 - - - -0.7586 0.978 221125_WJC_METTL3_EV_vs_WT_F03.09921.09921.2 0.0914 12-Jul K.VWQVDTK.E "sp|Q13685|AAMP_HUMAN,tr|C9JG97|C9JG97_HUMAN,tr|C9JEH3|C9JEH3_HUMAN,tr|C9JTS3|C9JTS3_HUMAN" 4 874.4549 0.65 26926 9921 2 874.45835 438.2347 Angio-associated migratory cell protein OS=Homo sapiens OX=9606 GN=AAMP PE=1 SV=2 5.81 2217.7 - 2.62E+06 - - - 3.9819 - 1.462 0.191 - 193.5 1 2 0 0.0035 7 0 0 0 7.90E+07 1.21E+08 - - - 1.6541 0.993 221125_WJC_METTL3_EV_vs_WT_F03.09922.09922.2 2.59 14-Jun K.AIQDVTIK.R "sp|Q8ND24|RN214_HUMAN,tr|E9PN76|E9PN76_HUMAN" 2 886.5124 1.75 26927 9922 2 886.511955 444.2635 RING finger protein 214 OS=Homo sapiens OX=9606 GN=RNF214 PE=1 SV=2 5.88 2217.7 - 2.08E+06 - - - -0.4828 - 1.203 0.173 - 110.5 1 2 0 -0.0004 8 0 0 0 8.80E+07 5.04E+07 - - - 0.876 0.9983 221125_WJC_METTL3_EV_vs_WT_F03.09928.09928.2 0.00353 16-Aug R.DVLLSSSSR.T sp|Q9Y2X9|ZN281_HUMAN 1 962.5033 1.27 26931 9928 2 962.500687 482.2589 Zinc finger protein 281 OS=Homo sapiens OX=9606 GN=ZNF281 PE=1 SV=1 5.84 2218.4 - 1.43E+06 - - - -2.6888 - 1.703 0.335 - 192.7 1 2 0 -0.0026 9 0 0 0 1.25E+08 9.77E+07 - - - 3.0547 0.997 221125_WJC_METTL3_EV_vs_WT_F03.09929.09929.2 0.0336 18-Sep K.GVLLTDGSEK[136.11].D "sp|P51532|SMCA4_HUMAN,tr|A0A2R8Y7S2|A0A2R8Y7S2_HUMAN,tr|A0A2R8Y7F3|A0A2R8Y7F3_HUMAN,tr|A0A2R8YGG3|A0A2R8YGG3_HUMAN,tr|A0A2R8Y523|A0A2R8Y523_HUMAN,tr|A0A2R8Y6V2|A0A2R8Y6V2_HUMAN,tr|Q9HBD4|Q9HBD4_HUMAN,tr|A0A2R8YCY3|A0A2R8YCY3_HUMAN,tr|A0A2R8Y440|A0A2R8Y440_HUMAN,tr|A0A2R8YDA1|A0A2R8YDA1_HUMAN,tr|A0A2R8Y7Y7|A0A2R8Y7Y7_HUMAN,tr|A0A2R8YF58|A0A2R8YF58_HUMAN,tr|A0A2R8Y526|A0A2R8Y526_HUMAN,tr|A0A2R8YG32|A0A2R8YG32_HUMAN,tr|A0A2R8YFV8|A0A2R8YFV8_HUMAN,tr|A0A2R8YGP5|A0A2R8YGP5_HUMAN,tr|A0A2R8Y6N0|A0A2R8Y6N0_HUMAN,tr|A0A2R8YF80|A0A2R8YF80_HUMAN,tr|A0A2R8Y4R6|A0A2R8Y4R6_HUMAN,tr|A0A2R8Y4P4|A0A2R8Y4P4_HUMAN,tr|A0A2R8Y4C5|A0A2R8Y4C5_HUMAN" 21 1025.5484 1.1 26932 9929 2 1025.545954 513.7815 Transcription activator BRG1 OS=Homo sapiens OX=9606 GN=SMARCA4 PE=1 SV=2 4.37 2218.5 - 1.27E+06 - - - -2.4241 - 1.73 0.242 - 168 1 2 0 -0.0025 10 0 0 0 3.77E+07 3.44E+07 - - - 2.3576 0.9997 221125_WJC_METTL3_EV_vs_WT_F03.09930.09930.2 0.000609 18-Sep R.LYNTESQSFR[166.11].K "sp|Q9NZJ0|DTL_HUMAN,tr|F5GZ90|F5GZ90_HUMAN" 2 1253.5916 1.03 26933 9930 2 1253.590801 627.8031 Denticleless protein homolog OS=Homo sapiens OX=9606 GN=DTL PE=1 SV=3 6 2218.6 - 512180 - - - -0.6262 - 1.892 0.402 - 238 1 2 0 -0.0008 10 0 0 0 1.24E+07 1.21E+07 - - - 3.7898 0.9998 221125_WJC_METTL3_EV_vs_WT_F03.09934.09934.2 0.000172 20-Nov R.MIAAVDTDSPR[166.11].E "sp|Q07812|BAX_HUMAN,tr|I6LPK7|I6LPK7_HUMAN,tr|K4JQN1|K4JQN1_HUMAN,tr|H0YA56|H0YA56_HUMAN" 4 1184.5735 0.89 26935 9934 2 1184.573489 593.294 Apoptosis regulator BAX OS=Homo sapiens OX=9606 GN=BAX PE=1 SV=1 4.21 2219.1 - 633079 - - - -0.0034 - 1.931 0.474 - 401.9 1 2 0 0 11 0 0 0 4.29E+07 4.83E+07 - - - 4.3221 1 221125_WJC_METTL3_EV_vs_WT_F03.09936.09936.2 6.44E-05 13/24 K.LLATEQEDAAVAK[136.11].S "sp|Q9P2E9|RRBP1_HUMAN,tr|A0A087WVV2|A0A087WVV2_HUMAN,tr|F8W7S5|F8W7S5_HUMAN" 3 1365.7231 1.43 26937 9936 2 1365.7215 683.8688 Ribosome-binding protein 1 OS=Homo sapiens OX=9606 GN=RRBP1 PE=1 SV=5 4.14 2219.4 - 542755 - - - -1.1789 - 2.931 0.542 - 519.6 1 2 0 -0.0016 13 0 0 0 1.88E+08 1.32E+08 - - - 5.8036 0.9998 221125_WJC_METTL3_EV_vs_WT_F03.09940.09940.2 1.07E-05 24-Nov K.LLATEQEDAAVAK.S "sp|Q9P2E9|RRBP1_HUMAN,tr|A0A087WVV2|A0A087WVV2_HUMAN,tr|F8W7S5|F8W7S5_HUMAN" 3 1357.7089 1.43 26938 9940 2 1357.708543 679.8617 Ribosome-binding protein 1 OS=Homo sapiens OX=9606 GN=RRBP1 PE=1 SV=5 4.14 2220 - 1.86E+06 - - - -0.2703 - 1.929 0.439 - 261 1 2 0 -0.0004 13 0 0 0 1.88E+08 1.32E+08 - - - 3.9696 0.8364 221125_WJC_METTL3_EV_vs_WT_F03.09944.09944.2 26.9 12-Jul K.R[166.11]GILTLK[136.11].Y "sp|Q6S8J3|POTEE_HUMAN,sp|P63261|ACTG_HUMAN,sp|P68133|ACTS_HUMAN,sp|P62736|ACTA_HUMAN,sp|P68032|ACTC_HUMAN,sp|P60709|ACTB_HUMAN,sp|P63267|ACTH_HUMAN,sp|A5A3E0|POTEF_HUMAN,sp|P0CG38|POTEI_HUMAN,sp|P0CG39|POTEJ_HUMAN,tr|A0A804GS07|A0A804GS07_HUMAN,tr|I3L3I0|I3L3I0_HUMAN,tr|G5E9R0|G5E9R0_HUMAN,tr|E7EVS6|E7EVS6_HUMAN,tr|A0A6Q8PFE4|A0A6Q8PFE4_HUMAN,tr|B8ZZJ2|B8ZZJ2_HUMAN,tr|J3KT65|J3KT65_HUMAN,tr|I3L3R2|I3L3R2_HUMAN,tr|K7EM38|K7EM38_HUMAN,tr|F6QUT6|F6QUT6_HUMAN,tr|C9JTX5|C9JTX5_HUMAN,tr|A0A6Q8PH58|A0A6Q8PH58_HUMAN,tr|F6UVQ4|F6UVQ4_HUMAN,tr|F8WB63|F8WB63_HUMAN,tr|I3L1U9|I3L1U9_HUMAN,tr|A0A804HKV3|A0A804HKV3_HUMAN,tr|A0A2R8Y793|A0A2R8Y793_HUMAN,tr|I3L4N8|I3L4N8_HUMAN,tr|C9JUM1|C9JUM1_HUMAN,tr|C9JZR7|C9JZR7_HUMAN,tr|C9JFL5|C9JFL5_HUMAN,tr|A0A2R8YGF8|A0A2R8YGF8_HUMAN,tr|A6NL76|A6NL76_HUMAN" 33 817.5504 0.84 26940 9944 2 817.547863 409.7825 POTE ankyrin domain family member E OS=Homo sapiens OX=9606 GN=POTEE PE=2 SV=3 11 2220.4 - 2.90E+06 - - - -3.1558 - 1.111 0.051 - 131.6 1 2 0 -0.0026 7 0 0 0 5.79E+08 6.90E+08 - - - -0.2496 0.9995 221125_WJC_METTL3_EV_vs_WT_F03.09945.09945.2 0.225 14-Aug K.LFNEVQEK[136.11].A "sp|Q9H0A0|NAT10_HUMAN,tr|A0A087WV29|A0A087WV29_HUMAN" 2 1013.5273 1.16 26941 9945 2 1013.527404 507.7709 RNA cytidine acetyltransferase OS=Homo sapiens OX=9606 GN=NAT10 PE=1 SV=2 4.53 2220.5 - 1.23E+06 - - - 0.0918 - 1.608 0.334 - 179.5 1 2 0 0.0001 8 0 0 0 7.47E+07 6.46E+07 - - - 2.9404 0.9973 221125_WJC_METTL3_EV_vs_WT_F03.09952.09952.2 0.154 14-Aug K.WQEPPPVK.Q "sp|Q8WWY3|PRP31_HUMAN,tr|E7EVX8|E7EVX8_HUMAN" 2 979.5127 4.24 26946 9952 2 979.511871 490.7636 U4\U6 small nuclear ribonucleoprotein Prp31 OS=Homo sapiens OX=9606 GN=PRPF31 PE=1 SV=2 6 2221.3 - 1.28E+06 - - - -0.8637 - 1.35 0.23 - 257.8 1 2 0 -0.0008 8 0 0 0 8.66E+07 2.04E+07 - - - 1.6446 0.9993 221125_WJC_METTL3_EV_vs_WT_F03.09957.09957.2 0.000695 14-Aug R.YDEYVNVK[136.11].D sp|Q8WUM4|PDC6I_HUMAN 1 1036.4957 1.09 26948 9957 2 1036.493159 519.2551 Programmed cell death 6-interacting protein OS=Homo sapiens OX=9606 GN=PDCD6IP PE=1 SV=1 4.37 2221.9 - 889669 - - - -2.4284 - 1.613 0.461 - 167.5 1 2 0 -0.0025 8 0 0 0 3.56E+07 3.28E+07 - - - 3.8871 0.7767 221125_WJC_METTL3_EV_vs_WT_F03.09963.09963.2 0.0255 16-Sep A.QAVGAIIGK[136.11].K "sp|Q9NZI8|IF2B1_HUMAN,sp|Q9Y6M1|IF2B2_HUMAN,tr|F8W930|F8W930_HUMAN" 3 863.532 1.66 26951 9963 2 863.529383 432.7733 Insulin-like growth factor 2 mRNA-binding protein 1 OS=Homo sapiens OX=9606 GN=IGF2BP1 PE=1 SV=2 8.75 2222.6 - 1.64E+06 - - - -3.0329 - 1.481 0.292 - 199.8 1 1 0 -0.0026 9 0 0 0 1.19E+08 7.17E+07 - - - 2.333 0.9996 221125_WJC_METTL3_EV_vs_WT_F03.09965.09965.2 0.00014 20-Sep K.VGTIDDDPEYR.K sp|Q9BZI7|REN3B_HUMAN 1 1278.5728 1.01 26953 9965 2 1278.569298 640.2937 Regulator of nonsense transcripts 3B OS=Homo sapiens OX=9606 GN=UPF3B PE=1 SV=1 3.84 2222.9 - 243634 - - - -2.7476 - 2.015 0.589 - 257 1 2 0 -0.0035 11 0 0 0 2.44E+07 2.42E+07 - - - 5.2856 0.999 221125_WJC_METTL3_EV_vs_WT_F03.09968.09968.2 0.0738 14-Jul K.TDISTALK[136.11].E "sp|P07197|NFM_HUMAN,tr|E7ESP9|E7ESP9_HUMAN,tr|E7EMV2|E7EMV2_HUMAN" 3 855.4793 2.38 26954 9968 2 855.478267 428.7469 Neurofilament medium polypeptide OS=Homo sapiens OX=9606 GN=NEFM PE=1 SV=3 5.5 2223.2 - 3.64E+06 - - - -1.2052 - 1.616 0.287 - 193.3 1 2 0 -0.001 8 0 0 0 2.66E+08 1.12E+08 - - - 2.608 0.9994 221125_WJC_METTL3_EV_vs_WT_F03.09970.09970.2 0.00425 14-Jul K.AFTELQAK[136.11].V "sp|O60925|PFD1_HUMAN,tr|E5RGS4|E5RGS4_HUMAN" 2 914.4953 1.77 26955 9970 2 914.494369 458.2549 Prefoldin subunit 1 OS=Homo sapiens OX=9606 GN=PFDN1 PE=1 SV=2 6.05 2223.5 - 3.96E+06 - - - -0.9995 - 1.456 0.379 - 125.8 1 2 0 -0.0009 8 0 0 0 2.90E+08 1.64E+08 - - - 2.9731 0.9996 221125_WJC_METTL3_EV_vs_WT_F03.09972.09972.2 0.000198 16-Sep R.DVLLSSSSR[166.11].T sp|Q9Y2X9|ZN281_HUMAN 1 972.5115 1.28 26957 9972 2 972.511664 487.263 Zinc finger protein 281 OS=Homo sapiens OX=9606 GN=ZNF281 PE=1 SV=1 5.84 2223.6 - 3.27E+06 - - - 0.1224 - 1.682 0.379 - 245.4 1 2 0 0.0001 9 0 0 0 1.25E+08 9.76E+07 - - - 3.3446 0.9996 221125_WJC_METTL3_EV_vs_WT_F03.09973.09973.2 0.0591 20-Oct R.NVLVSEDNVAK.V sp|P41240|CSK_HUMAN 1 1186.6194 0.54 26958 9973 2 1186.621277 594.317 Tyrosine-protein kinase CSK OS=Homo sapiens OX=9606 GN=CSK PE=1 SV=1 4.37 2223.8 - 518633 - - - 1.6096 - 1.913 0.436 - 271.5 1 2 0 0.0019 11 0 0 0 1.02E+07 1.91E+07 - - - 4.0155 0.9994 221125_WJC_METTL3_EV_vs_WT_F03.09979.09979.2 0.00616 16-Sep R.ALQSYYEAK.A "sp|Q5TAP6|UT14C_HUMAN,sp|Q9BVJ6|UT14A_HUMAN,tr|X6RJY0|X6RJY0_HUMAN" 3 1071.5237 2.14 26962 9979 2 1071.523461 536.7691 U3 small nucleolar RNA-associated protein 14 homolog C OS=Homo sapiens OX=9606 GN=UTP14C PE=1 SV=1 6.04 2224.4 - 2.63E+06 - - - -0.2006 - 1.608 0.337 - 206.4 1 2 0 -0.0002 9 0 0 0 7.05E+07 3.29E+07 - - - 2.9042 1 221125_WJC_METTL3_EV_vs_WT_F03.09980.09980.3 0.000269 14/40 K.VLIVYAHQEPK[136.11].S "sp|P16083|NQO2_HUMAN,tr|Q5TD07|Q5TD07_HUMAN,tr|Q5TD05|Q5TD05_HUMAN,tr|A2A2U4|A2A2U4_HUMAN" 4 1303.738 1.17 26963 9980 3 1303.736264 435.5866 Ribosyldihydronicotinamide dehydrogenase [quinone] OS=Homo sapiens OX=9606 GN=NQO2 PE=1 SV=5 6.72 2224.5 - 1.26E+06 - - - -1.3101 - 2.623 0.434 - 303.7 1 2 0 -0.0017 11 0 0 0 1.23E+08 1.04E+08 - - - 6.1177 0.9936 221125_WJC_METTL3_EV_vs_WT_F03.09981.09981.2 0.441 12-Jul K.SFTEQLR.K sp|Q9UKV8|AGO2_HUMAN 1 879.445 4.96 26964 9981 2 879.444025 440.7298 Protein argonaute-2 OS=Homo sapiens OX=9606 GN=AGO2 PE=1 SV=3 5.72 2224.6 - 847069 - - - -1.1439 - 1.314 0.162 - 207 1 2 0 -0.001 7 0 0 0 3.30E+07 6.66E+06 - - - 1.1025 0.9978 221125_WJC_METTL3_EV_vs_WT_F03.09982.09982.2 0.00737 18-Jun R.LISENSVYEK.R sp|Q13111|CAF1A_HUMAN 1 1180.5976 0.56 26965 9982 2 1180.597369 591.3061 Chromatin assembly factor 1 subunit A OS=Homo sapiens OX=9606 GN=CHAF1A PE=1 SV=3 4.53 2224.7 - 196220 - - - -0.1694 - 1.255 0.274 - 63.8 1 2 0 -0.0002 10 0 0 0 1.38E+07 2.45E+07 - - - 1.6987 0.9994 221125_WJC_METTL3_EV_vs_WT_F03.09984.09984.2 0.0631 14-Oct K.SIEVIENR[166.11].M "sp|P49321|NASP_HUMAN,tr|H0YDS9|H0YDS9_HUMAN,tr|Q5T624|Q5T624_HUMAN,tr|H0YF33|H0YF33_HUMAN,tr|E9PRH9|E9PRH9_HUMAN" 5 968.5166 0.5 26966 9984 2 968.516303 485.2656 Nuclear autoantigenic sperm protein OS=Homo sapiens OX=9606 GN=NASP PE=1 SV=2 4.53 2225 - 4.18E+06 - - - -0.3376 - 1.97 0.233 - 360.4 1 2 0 -0.0003 8 0 0 0 4.95E+07 9.89E+07 - - - 2.8068 0.995 221125_WJC_METTL3_EV_vs_WT_F03.09986.09986.2 0.375 16-Aug K.LAADHPFLK.E "sp|Q96QA5|GSDMA_HUMAN,tr|J3KRG2|J3KRG2_HUMAN" 2 1010.5549 38.8 26967 9986 2 1010.555111 506.2847 Gasdermin-A OS=Homo sapiens OX=9606 GN=GSDMA PE=1 SV=4 6.74 2225.2 - 809587 - - - 0.193 - 1.565 0.106 - 123.5 1 2 0 0.0002 9 0 0 0 3.90E+07 1.00E+06 - - - 1.1196 0.9995 221125_WJC_METTL3_EV_vs_WT_F03.09988.09988.2 0.0103 14-Jul K.YGETC[160.03]FPK[136.11].G sp|P17028|ZNF24_HUMAN 1 1008.4466 1.07 26969 9988 2 1008.446004 505.2306 Zinc finger protein 24 OS=Homo sapiens OX=9606 GN=ZNF24 PE=1 SV=4 5.99 2225.4 - 855478 - - - -0.6089 - 1.484 0.378 - 134.6 1 2 0 -0.0006 8 0 0 0 4.10E+07 3.84E+07 - - - 3.0232 1 221125_WJC_METTL3_EV_vs_WT_F03.09992.09992.3 0.00243 14/40 K.VLIVYAHQEPK.S "sp|P16083|NQO2_HUMAN,tr|Q5TD07|Q5TD07_HUMAN,tr|Q5TD05|Q5TD05_HUMAN,tr|A2A2U4|A2A2U4_HUMAN" 4 1295.7238 1.17 26971 9992 3 1295.722469 432.9152 Ribosyldihydronicotinamide dehydrogenase [quinone] OS=Homo sapiens OX=9606 GN=NQO2 PE=1 SV=5 6.72 2225.9 - 2.12E+06 - - - -1.0056 - 2.508 0.469 - 314.2 1 2 0 -0.0013 11 0 0 0 1.23E+08 1.04E+08 - - - 6.3806 0.7904 221125_WJC_METTL3_EV_vs_WT_F03.09998.09998.2 0.0347 14-Jul R.PSTYGIPR[166.11].L "sp|P78347|GTF2I_HUMAN,tr|A0A494C0Q7|A0A494C0Q7_HUMAN,tr|A0A494C1K3|A0A494C1K3_HUMAN" 3 899.474 0.93 26975 9998 2 899.47653 450.7443 General transcription factor II-I OS=Homo sapiens OX=9606 GN=GTF2I PE=1 SV=2 9.18 2226.6 - 1.10E+06 - - - 2.7716 - 1.619 0.24 - 133.9 1 1 0 0.0025 8 0 0 0 3.55E+07 3.82E+07 - - - 2.266 0.9999 221125_WJC_METTL3_EV_vs_WT_F03.09999.09999.2 0.000449 20-Sep K.VGTIDDDPEYR[166.11].K sp|Q9BZI7|REN3B_HUMAN 1 1288.5811 1.11 26976 9999 2 1288.581676 645.2978 Regulator of nonsense transcripts 3B OS=Homo sapiens OX=9606 GN=UPF3B PE=1 SV=1 3.84 2226.7 - 581489 - - - 0.4617 - 2.097 0.527 - 292.6 1 2 0 0.0006 11 0 0 0 2.44E+07 2.20E+07 - - - 4.9365 0.9964 221125_WJC_METTL3_EV_vs_WT_F03.10002.10002.2 0.11 14-Jul R.AEFTVETR.S "sp|P21333|FLNA_HUMAN,tr|A0A7P0NMY4|A0A7P0NMY4_HUMAN,tr|Q60FE5|Q60FE5_HUMAN,tr|A0A7I2V3E6|A0A7I2V3E6_HUMAN,tr|A0A087WWY3|A0A087WWY3_HUMAN,tr|F8WE98|F8WE98_HUMAN" 6 951.4662 1.17 26977 10002 2 951.465408 476.7404 Filamin-A OS=Homo sapiens OX=9606 GN=FLNA PE=1 SV=4 4.53 2227.1 - 2.29E+06 - - - -0.7914 - 1.359 0.197 - 142.3 1 2 0 -0.0008 8 0 0 0 5.32E+07 4.55E+07 - - - 1.4209 0.9542 221125_WJC_METTL3_EV_vs_WT_F03.10003.10003.2 0.234 16-Oct R.LQQENSILR[166.11].D "sp|Q9P2E9|RRBP1_HUMAN,sp|Q8N4C6|NIN_HUMAN,tr|E9PN67|E9PN67_HUMAN,tr|A0A087WVV2|A0A087WVV2_HUMAN,tr|C9J066|C9J066_HUMAN,tr|F8W7S5|F8W7S5_HUMAN,tr|H9KV85|H9KV85_HUMAN" 7 1109.6068 1.48 26978 10003 2 1109.602482 555.8107 Ribosome-binding protein 1 OS=Homo sapiens OX=9606 GN=RRBP1 PE=1 SV=5 6 2227.2 - 868926 - - - -3.9293 - 1.723 0.059 - 335 1 2 0 -0.0044 9 0 0 0 1.19E+08 8.05E+07 - - - 1.0494 0.9998 221125_WJC_METTL3_EV_vs_WT_F03.10004.10004.2 0.000116 18-Sep K.LTSLNEEYTK[136.11].N "sp|P43246|MSH2_HUMAN,tr|A0A2R8YG02|A0A2R8YG02_HUMAN,tr|E9PHA6|E9PHA6_HUMAN,tr|A0A2R8YFH0|A0A2R8YFH0_HUMAN,tr|A0A2R8Y6P0|A0A2R8Y6P0_HUMAN" 5 1204.6067 0.85 26979 10004 2 1204.607551 603.3106 DNA mismatch repair protein Msh2 OS=Homo sapiens OX=9606 GN=MSH2 PE=1 SV=1 4.53 2227.3 - 488799 - - - 0.7197 - 1.927 0.436 - 237.7 1 2 0 0.0009 10 0 0 0 2.87E+07 3.39E+07 - - - 4.092 0.9904 221125_WJC_METTL3_EV_vs_WT_F03.10008.10008.2 2.71 12-Aug K.RGILTLK.Y "sp|Q6S8J3|POTEE_HUMAN,sp|P63261|ACTG_HUMAN,sp|P68133|ACTS_HUMAN,sp|P62736|ACTA_HUMAN,sp|P68032|ACTC_HUMAN,sp|P60709|ACTB_HUMAN,sp|P63267|ACTH_HUMAN,sp|A5A3E0|POTEF_HUMAN,sp|P0CG38|POTEI_HUMAN,sp|P0CG39|POTEJ_HUMAN,tr|A0A804GS07|A0A804GS07_HUMAN,tr|I3L3I0|I3L3I0_HUMAN,tr|G5E9R0|G5E9R0_HUMAN,tr|E7EVS6|E7EVS6_HUMAN,tr|A0A6Q8PFE4|A0A6Q8PFE4_HUMAN,tr|B8ZZJ2|B8ZZJ2_HUMAN,tr|J3KT65|J3KT65_HUMAN,tr|I3L3R2|I3L3R2_HUMAN,tr|K7EM38|K7EM38_HUMAN,tr|F6QUT6|F6QUT6_HUMAN,tr|C9JTX5|C9JTX5_HUMAN,tr|A0A6Q8PH58|A0A6Q8PH58_HUMAN,tr|F6UVQ4|F6UVQ4_HUMAN,tr|F8WB63|F8WB63_HUMAN,tr|I3L1U9|I3L1U9_HUMAN,tr|A0A804HKV3|A0A804HKV3_HUMAN,tr|A0A2R8Y793|A0A2R8Y793_HUMAN,tr|I3L4N8|I3L4N8_HUMAN,tr|C9JUM1|C9JUM1_HUMAN,tr|C9JZR7|C9JZR7_HUMAN,tr|C9JFL5|C9JFL5_HUMAN,tr|A0A2R8YGF8|A0A2R8YGF8_HUMAN,tr|A6NL76|A6NL76_HUMAN" 33 799.528 0.84 26981 10008 2 799.528122 400.7713 POTE ankyrin domain family member E OS=Homo sapiens OX=9606 GN=POTEE PE=2 SV=3 11 2227.9 - 1.67E+07 - - - 0.1864 - 1.536 0.035 - 307.2 1 2 0 0.0001 7 0 0 0 5.78E+08 6.90E+08 - - - 0.6593 0.9992 221125_WJC_METTL3_EV_vs_WT_F03.10009.10009.2 0.00362 16-Sep R.QAILETPDR.Q "sp|Q8IVH2|FOXP4_HUMAN,tr|B7ZBM3|B7ZBM3_HUMAN" 2 1041.5455 0.36 26982 10009 2 1041.542653 521.78 Forkhead box protein P4 OS=Homo sapiens OX=9606 GN=FOXP4 PE=1 SV=1 4.37 2227.9 - 1.06E+06 - - - -2.7085 - 2.162 0.353 - 308.8 1 2 0 -0.0028 9 0 0 0 3.84E+07 1.07E+08 - - - 3.878 0.9994 221125_WJC_METTL3_EV_vs_WT_F03.10014.10014.2 0.00122 18-Sep K.LTSLNEEYTK.N "sp|P43246|MSH2_HUMAN,tr|A0A2R8YG02|A0A2R8YG02_HUMAN,tr|E9PHA6|E9PHA6_HUMAN,tr|A0A2R8YFH0|A0A2R8YFH0_HUMAN,tr|A0A2R8Y6P0|A0A2R8Y6P0_HUMAN" 5 1196.5925 0.84 26985 10014 2 1196.589587 599.3035 DNA mismatch repair protein Msh2 OS=Homo sapiens OX=9606 GN=MSH2 PE=1 SV=1 4.53 2228.6 - 472908 - - - -2.421 - 1.844 0.434 - 117.8 1 2 0 -0.0029 10 0 0 0 3.01E+07 3.57E+07 - - - 3.9537 0.9993 221125_WJC_METTL3_EV_vs_WT_F03.10015.10015.2 0.00587 16-Aug K.YALTGDEVK[136.11].K "sp|P62701|RS4X_HUMAN,sp|P22090|RS4Y1_HUMAN,sp|Q8TD47|RS4Y2_HUMAN,tr|C9JEH7|C9JEH7_HUMAN" 4 1002.5113 1.04 26986 10015 2 1002.510922 502.2629 "40S ribosomal protein S4, X isoform OS=Homo sapiens OX=9606 GN=RPS4X PE=1 SV=2" 4.37 2228.6 - 2.31E+06 - - - -0.404 - 1.525 0.328 - 162 1 2 0 -0.0004 9 0 0 0 4.34E+08 4.19E+08 - - - 2.6843 0.9995 221125_WJC_METTL3_EV_vs_WT_F03.10017.10017.2 0.000518 20-Oct K.VLIVYAHQEPK.S "sp|P16083|NQO2_HUMAN,tr|Q5TD07|Q5TD07_HUMAN,tr|Q5TD05|Q5TD05_HUMAN,tr|A2A2U4|A2A2U4_HUMAN" 4 1295.7238 1.15 26988 10017 2 1295.726444 648.8692 Ribosyldihydronicotinamide dehydrogenase [quinone] OS=Homo sapiens OX=9606 GN=NQO2 PE=1 SV=5 6.72 2228.8 - 240248 - - - 2.0622 - 2.127 0.391 - 401.2 1 2 0 0.0027 11 0 0 0 6.34E+06 5.52E+06 - - - 3.9698 0.9984 221125_WJC_METTL3_EV_vs_WT_F03.10028.10028.2 0.0574 12-Jun K.DDPVDLR.L "sp|Q9Y2W1|TR150_HUMAN,tr|A0A3B3ITZ9|A0A3B3ITZ9_HUMAN" 2 828.3977 2.35 26995 10028 2 828.39824 415.2061 Thyroid hormone receptor-associated protein 3 OS=Homo sapiens OX=9606 GN=THRAP3 PE=1 SV=2 3.93 2230.1 - 1.30E+07 - - - 0.5951 - 1.262 0.311 - 224.9 1 2 0 0.0005 7 0 0 0 2.79E+08 1.19E+08 - - - 2.0752 0.9883 221125_WJC_METTL3_EV_vs_WT_F03.10029.10029.2 0.21 14-May R.QYVQGC[160.03]GV.- sp|P61626|LYSC_HUMAN 1 909.4015 - 26996 10029 2 909.40156 455.708 Lysozyme C OS=Homo sapiens OX=9606 GN=LYZ PE=1 SV=1 5.52 2230.2 - 1.58E+06 - - - 0.1188 - 1.003 0.199 - 98.4 1 2 0 0.0001 8 0 0 0 - - - - - 0.5198 0.9855 221125_WJC_METTL3_EV_vs_WT_F03.10037.10037.2 0.366 14-Jun K.FANLTPSR.T "sp|O15027|SC16A_HUMAN,tr|A0A3F2YNX0|A0A3F2YNX0_HUMAN,tr|A0A3F2YNZ0|A0A3F2YNZ0_HUMAN,tr|X6RGP5|X6RGP5_HUMAN,tr|F1T0I1|F1T0I1_HUMAN,tr|A0A0C4DH09|A0A0C4DH09_HUMAN" 6 904.4767 1.75 27002 10037 2 904.47704 453.2456 Protein transport protein Sec16A OS=Homo sapiens OX=9606 GN=SEC16A PE=1 SV=4 9.75 2231.1 - 720827 - - - 0.4135 - 1.091 0.15 - 86.1 1 2 0 0.0004 8 0 0 0 2.75E+08 1.57E+08 - - - 0.4115 0.9988 221125_WJC_METTL3_EV_vs_WT_F03.10038.10038.2 0.00785 16-Aug K.IPTTFENGR.C "sp|P05090|APOD_HUMAN,tr|C9JF17|C9JF17_HUMAN,tr|C9JX71|C9JX71_HUMAN" 3 1033.5193 205.34 27003 10038 2 1033.516973 517.7669 Apolipoprotein D OS=Homo sapiens OX=9606 GN=APOD PE=1 SV=1 6 2231.1 - 1.84E+06 - - - -2.2119 - 1.596 0.358 - 241.3 1 2 0 -0.0023 9 0 0 0 3.12E+08 1.52E+06 - - - 3.037 0.9997 221125_WJC_METTL3_EV_vs_WT_F03.10039.10039.3 0.00235 Oct-32 K.LR[166.11]PGFMEDR[166.11].G sp|Q5BKZ1|ZN326_HUMAN 1 1139.5661 0.001 27004 10039 3 1139.565081 380.8626 DBIRD complex subunit ZNF326 OS=Homo sapiens OX=9606 GN=ZNF326 PE=1 SV=2 6.07 2231.2 - 858020 - - - -0.853 - 1.989 0.336 - 164.9 1 2 0 -0.001 9 0 0 0 0.00E+00 1.71E+07 - - - 4.3582 0.9995 221125_WJC_METTL3_EV_vs_WT_F03.10040.10040.2 0.000732 20-Sep K.VLIVYAHQEPK[136.11].S "sp|P16083|NQO2_HUMAN,tr|Q5TD07|Q5TD07_HUMAN,tr|Q5TD05|Q5TD05_HUMAN,tr|A2A2U4|A2A2U4_HUMAN" 4 1303.738 1.15 27005 10040 2 1303.738242 652.8763 Ribosyldihydronicotinamide dehydrogenase [quinone] OS=Homo sapiens OX=9606 GN=NQO2 PE=1 SV=5 6.72 2231.4 - 203079 - - - 0.2071 - 1.909 0.31 - 261.9 1 2 0 0.0003 11 0 0 0 6.34E+06 5.52E+06 - - - 3.0797 0.9998 221125_WJC_METTL3_EV_vs_WT_F03.10043.10043.2 0.00179 16-Aug K.YALTGDEVK.K "sp|P62701|RS4X_HUMAN,sp|P22090|RS4Y1_HUMAN,sp|Q8TD47|RS4Y2_HUMAN,tr|C9JEH7|C9JEH7_HUMAN" 4 994.4971 1.03 27006 10043 2 994.497379 498.2558 "40S ribosomal protein S4, X isoform OS=Homo sapiens OX=9606 GN=RPS4X PE=1 SV=2" 4.37 2231.8 - 1.13E+07 - - - 0.2534 - 1.555 0.502 - 185.1 1 2 0 0.0003 9 0 0 0 4.34E+08 4.23E+08 - - - 4.0259 0.9998 221125_WJC_METTL3_EV_vs_WT_F03.10044.10044.2 0.000132 20-Sep R.GVSAVVVGADR.V sp|Q9BV20|MTNA_HUMAN 1 1028.5615 1.03 27007 10044 2 1028.561742 515.288 Methylthioribose-1-phosphate isomerase OS=Homo sapiens OX=9606 GN=MRI1 PE=1 SV=1 5.84 2231.8 - 1.50E+06 - - - 0.2761 - 2.066 0.466 - 370.3 1 2 0 0.0003 11 0 0 0 3.54E+07 3.45E+07 - - - 4.4457 0.8847 221125_WJC_METTL3_EV_vs_WT_F03.10045.10045.2 0.0881 16-Aug F.IQNVPLEDR[166.11].V "sp|Q00839|HNRPU_HUMAN,tr|A0A1W2PQL0|A0A1W2PQL0_HUMAN,tr|A0A1W2PPL4|A0A1W2PPL4_HUMAN,tr|A0A1W2PQ74|A0A1W2PQ74_HUMAN,tr|Q5RI18|Q5RI18_HUMAN,tr|A0A1W2PP35|A0A1W2PP35_HUMAN,tr|A0A1W2PPS1|A0A1W2PPS1_HUMAN,tr|A0A1W2PRZ7|A0A1W2PRZ7_HUMAN,tr|A0A1W2PPH7|A0A1W2PPH7_HUMAN,tr|A0A1W2PQD4|A0A1W2PQD4_HUMAN,tr|A0A1W2PP34|A0A1W2PP34_HUMAN,tr|A0A1X7SBS1|A0A1X7SBS1_HUMAN" 12 1092.5803 1.1 27008 10045 2 1092.578469 547.2974 Heterogeneous nuclear ribonucleoprotein U OS=Homo sapiens OX=9606 GN=HNRNPU PE=1 SV=6 4.37 2231.9 - 1.69E+06 - - - -1.6694 - 1.777 0.199 - 241.1 1 1 0 -0.0018 9 0 0 0 1.22E+08 1.11E+08 - - - 2.1735 0.9992 221125_WJC_METTL3_EV_vs_WT_F03.10046.10046.2 0.0931 14-Aug K.LQEEMLQR[166.11].E "sp|P08670|VIME_HUMAN,tr|B0YJC5|B0YJC5_HUMAN,tr|B0YJC4|B0YJC4_HUMAN" 3 1055.5309 1.84 27009 10046 2 1055.529776 528.7727 Vimentin OS=Homo sapiens OX=9606 GN=VIM PE=1 SV=4 4.53 2231.9 - 1.30E+06 - - - -1.0649 - 1.839 0.25 - 249.6 1 2 0 -0.0011 8 0 0 0 3.84E+09 2.08E+09 - - - 2.7245 0.9998 221125_WJC_METTL3_EV_vs_WT_F03.10047.10047.2 0.00143 14/20 R.GVSAVVVGADR[166.11].V sp|Q9BV20|MTNA_HUMAN 1 1038.5697 1.44 27010 10047 2 1038.571115 520.2921 Methylthioribose-1-phosphate isomerase OS=Homo sapiens OX=9606 GN=MRI1 PE=1 SV=1 5.84 2232 - 815866 - - - 1.3355 - 2.576 0.43 - 852.2 1 2 0 0.0014 11 0 0 0 3.51E+07 2.44E+07 - - - 4.7763 0.9966 221125_WJC_METTL3_EV_vs_WT_F03.10048.10048.2 0.0951 14-Jul R.EFQEEIAR.L "sp|O14782|KIF3C_HUMAN,sp|O15066|KIF3B_HUMAN,tr|F8WER6|F8WER6_HUMAN,tr|F8WAR6|F8WAR6_HUMAN" 4 1020.4876 0.72 27011 10048 2 1020.488626 511.2511 Kinesin-like protein KIF3C OS=Homo sapiens OX=9606 GN=KIF3C PE=1 SV=3 4.25 2232.1 - 407636 - - - 0.9819 - 1.368 0.217 - 207.6 1 2 0 0.001 8 0 0 0 9.66E+06 1.35E+07 - - - 1.5885 0.9684 221125_WJC_METTL3_EV_vs_WT_F03.10054.10054.2 0.00013 16-Oct F.IQNVPLEDR.V "sp|Q00839|HNRPU_HUMAN,tr|A0A1W2PQL0|A0A1W2PQL0_HUMAN,tr|A0A1W2PPL4|A0A1W2PPL4_HUMAN,tr|A0A1W2PQ74|A0A1W2PQ74_HUMAN,tr|Q5RI18|Q5RI18_HUMAN,tr|A0A1W2PP35|A0A1W2PP35_HUMAN,tr|A0A1W2PPS1|A0A1W2PPS1_HUMAN,tr|A0A1W2PRZ7|A0A1W2PRZ7_HUMAN,tr|A0A1W2PPH7|A0A1W2PPH7_HUMAN,tr|A0A1W2PQD4|A0A1W2PQD4_HUMAN,tr|A0A1W2PP34|A0A1W2PP34_HUMAN,tr|A0A1X7SBS1|A0A1X7SBS1_HUMAN" 12 1082.572 1.1 27015 10054 2 1082.574459 542.2933 Heterogeneous nuclear ribonucleoprotein U OS=Homo sapiens OX=9606 GN=HNRNPU PE=1 SV=6 4.37 2232.8 - 2.15E+06 - - - 2.2502 - 2.052 0.402 - 423.9 1 1 0 0.0024 9 0 0 0 1.22E+08 1.11E+08 - - - 4.089 0.998 221125_WJC_METTL3_EV_vs_WT_F03.10055.10055.2 0.269 12-Sep R.HLQLAIR.N "sp|P16104|H2AX_HUMAN,sp|Q9BTM1|H2AJ_HUMAN,sp|Q93077|H2A1C_HUMAN,sp|Q99878|H2A1J_HUMAN,sp|Q16777|H2A2C_HUMAN,sp|Q96QV6|H2A1A_HUMAN,sp|P0C0S5|H2AZ_HUMAN,sp|P04908|H2A1B_HUMAN,sp|P20671|H2A1D_HUMAN,sp|P0C0S8|H2A1_HUMAN,sp|Q6FI13|H2A2A_HUMAN,sp|Q96KK5|H2A1H_HUMAN,sp|Q71UI9|H2AV_HUMAN,sp|Q7L7L0|H2A3_HUMAN,tr|C9J386|C9J386_HUMAN,tr|A0A0U1RR32|A0A0U1RR32_HUMAN,tr|A0A0U1RRH7|A0A0U1RRH7_HUMAN,tr|A0A3B3IS11|A0A3B3IS11_HUMAN,tr|H0YFX9|H0YFX9_HUMAN,tr|C9J0D1|C9J0D1_HUMAN,tr|A0A494C189|A0A494C189_HUMAN" 21 849.5185 1.14 27016 10055 2 849.518689 425.7665 Histone H2AX OS=Homo sapiens OX=9606 GN=H2AX PE=1 SV=2 9.76 2232.9 - 1.98E+06 - - - 0.2566 - 1.767 0.132 - 294.3 1 2 0 0.0002 7 0 0 0 5.75E+09 5.04E+09 - - - 1.8197 0.8442 221125_WJC_METTL3_EV_vs_WT_F03.10057.10057.3 0.136 Jul-44 K.DLNPFTPLVGIR.L sp|Q86U90|YRDC_HUMAN 1 1340.7452 1.05 27018 10057 3 1340.749741 447.9224 "YrdC domain-containing protein, mitochondrial OS=Homo sapiens OX=9606 GN=YRDC PE=1 SV=1" 5.84 2233 - 790509 - - - 3.3601 - 1.394 0.143 - 74.5 1 2 0 0.0045 12 0 0 0 1.44E+08 1.37E+08 - - - 1.0538 0.9844 221125_WJC_METTL3_EV_vs_WT_F03.10059.10059.2 0.796 12-Jul K.TSLFSSK.L sp|Q9BTX1|NDC1_HUMAN 1 768.4018 1.04 27020 10059 2 768.402063 385.2082 Nucleoporin NDC1 OS=Homo sapiens OX=9606 GN=NDC1 PE=1 SV=2 8.41 2233.2 - 641677 - - - 0.3813 - 1.231 0.089 - 183.3 1 2 0 0.0003 7 0 0 0 4.48E+07 4.30E+07 - - - 0.3568 0.9975 221125_WJC_METTL3_EV_vs_WT_F03.10061.10061.2 0.0215 12-Jul K.DNNLLGR[166.11].F "sp|P0DMV8|HS71A_HUMAN,sp|P34931|HS71L_HUMAN,sp|P0DMV9|HS71B_HUMAN,sp|P17066|HSP76_HUMAN,tr|Q53FA3|Q53FA3_HUMAN,tr|V9GZ37|V9GZ37_HUMAN,tr|A0A0G2JIW1|A0A0G2JIW1_HUMAN" 7 810.4223 1.65 27022 10061 2 810.422392 406.2184 Heat shock 70 kDa protein 1A OS=Homo sapiens OX=9606 GN=HSPA1A PE=1 SV=1 5.84 2233.4 - 412244 - - - 0.0691 - 1.236 0.26 - 179.6 1 2 0 0.0001 7 0 0 0 1.21E+08 7.33E+07 - - - 1.6327 0.9982 221125_WJC_METTL3_EV_vs_WT_F03.10067.10067.2 0.522 12-Oct R.HLQLAIR[166.11].N "sp|P16104|H2AX_HUMAN,sp|Q9BTM1|H2AJ_HUMAN,sp|Q93077|H2A1C_HUMAN,sp|Q99878|H2A1J_HUMAN,sp|Q16777|H2A2C_HUMAN,sp|Q96QV6|H2A1A_HUMAN,sp|P0C0S5|H2AZ_HUMAN,sp|P04908|H2A1B_HUMAN,sp|P20671|H2A1D_HUMAN,sp|P0C0S8|H2A1_HUMAN,sp|Q6FI13|H2A2A_HUMAN,sp|Q96KK5|H2A1H_HUMAN,sp|Q71UI9|H2AV_HUMAN,sp|Q7L7L0|H2A3_HUMAN,tr|C9J386|C9J386_HUMAN,tr|A0A0U1RR32|A0A0U1RR32_HUMAN,tr|A0A0U1RRH7|A0A0U1RRH7_HUMAN,tr|A0A3B3IS11|A0A3B3IS11_HUMAN,tr|H0YFX9|H0YFX9_HUMAN,tr|C9J0D1|C9J0D1_HUMAN,tr|A0A494C189|A0A494C189_HUMAN" 21 859.5267 1.14 27026 10067 2 859.526818 430.7706 Histone H2AX OS=Homo sapiens OX=9606 GN=H2AX PE=1 SV=2 9.76 2234.1 - 7.92E+06 - - - 0.0896 - 1.69 0.159 - 376.8 1 2 0 0.0001 7 0 0 0 5.75E+09 5.04E+09 - - - 1.878 0.994 221125_WJC_METTL3_EV_vs_WT_F03.10074.10074.2 0.757 16-Jul R.VPPPPPIAR.A "sp|P07910|HNRPC_HUMAN,tr|B4DY08|B4DY08_HUMAN,tr|G3V575|G3V575_HUMAN,tr|G3V5V7|G3V5V7_HUMAN,tr|B2R5W2|B2R5W2_HUMAN,tr|G3V4C1|G3V4C1_HUMAN,tr|G3V576|G3V576_HUMAN,tr|G3V2D6|G3V2D6_HUMAN,tr|G3V4W0|G3V4W0_HUMAN,tr|G3V555|G3V555_HUMAN,tr|G3V2Q1|G3V2Q1_HUMAN" 11 942.5651 1.93 27031 10074 2 942.565228 472.2898 Heterogeneous nuclear ribonucleoproteins C1\C2 OS=Homo sapiens OX=9606 GN=HNRNPC PE=1 SV=4 9.72 2235 - 2.96E+06 - - - 0.1496 - 1.176 0.199 - 146.3 1 2 0 0.0001 9 0 0 0 1.71E+08 8.87E+07 - - - 0.9798 0.9739 221125_WJC_METTL3_EV_vs_WT_F03.10075.10075.2 1.28 16-Jul K.AGVAPLQVK.V "sp|P21333|FLNA_HUMAN,tr|Q60FE5|Q60FE5_HUMAN" 2 881.5335 0.97 27032 10075 2 881.533743 441.774 Filamin-A OS=Homo sapiens OX=9606 GN=FLNA PE=1 SV=4 8.8 2235.1 - 1.20E+06 - - - 0.3301 - 1.137 0.081 - 116.2 1 2 0 0.0003 9 0 0 0 1.07E+08 1.10E+08 - - - 0.0106 0.9998 221125_WJC_METTL3_EV_vs_WT_F03.10076.10076.2 0.000219 14-Sep K.ISDDLMQK.L "sp|O43242|PSMD3_HUMAN,tr|H0YGV8|H0YGV8_HUMAN" 2 948.4586 0.8 27033 10076 2 948.458751 475.2366 26S proteasome non-ATPase regulatory subunit 3 OS=Homo sapiens OX=9606 GN=PSMD3 PE=1 SV=2 4.21 2235.2 - 905481 - - - 0.1244 - 1.672 0.459 - 169.4 1 2 0 0.0001 8 0 0 0 3.68E+07 4.59E+07 - - - 3.9814 0.9036 221125_WJC_METTL3_EV_vs_WT_F03.10077.10077.2 0.0312 14-May Q.MC[160.03]NPIITK.L "sp|P34931|HS71L_HUMAN,tr|Q53FA3|Q53FA3_HUMAN" 2 975.4882 0.35 27034 10077 2 975.488265 488.7514 Heat shock 70 kDa protein 1-like OS=Homo sapiens OX=9606 GN=HSPA1L PE=1 SV=2 7.98 2235.2 - 832685 - - - 0.1087 - 1.256 0.293 - 72.6 1 1 0 0.0001 8 0 0 0 1.36E+08 3.84E+08 - - - 1.8925 0.9991 221125_WJC_METTL3_EV_vs_WT_F03.10080.10080.2 0.0105 20-Aug K.ELAAQLNEEAK[136.11].R sp|Q9Y5B9|SP16H_HUMAN 1 1222.6285 3.69 27035 10080 2 1222.628904 612.3215 FACT complex subunit SPT16 OS=Homo sapiens OX=9606 GN=SUPT16H PE=1 SV=1 4.25 2235.7 - 249247 - - - 0.3452 - 1.494 0.322 - 139.5 1 2 0 0.0004 11 0 0 0 4.17E+07 1.13E+07 - - - 2.5052 0.9987 221125_WJC_METTL3_EV_vs_WT_F03.10087.10087.2 0.14 16-Aug R.NIVEAAAVR[166.11].D "sp|Q5JNZ5|RS26L_HUMAN,sp|P62854|RS26_HUMAN" 2 951.5377 0.98 27039 10087 2 951.537898 476.7761 Putative 40S ribosomal protein S26-like 1 OS=Homo sapiens OX=9606 GN=RPS26P11 PE=5 SV=1 6 2236.5 - 2.68E+06 - - - 0.2081 - 1.459 0.278 - 201.2 1 2 0 0.0002 9 0 0 0 3.53E+08 3.59E+08 - - - 2.1871 0.9971 221125_WJC_METTL3_EV_vs_WT_F03.10088.10088.2 0.209 14-Jul R.ELQC[160.03]LTPR[166.11].G "sp|Q08945|SSRP1_HUMAN,tr|E9PMD4|E9PMD4_HUMAN" 2 1025.5203 1.12 27040 10088 2 1025.519848 513.7674 FACT complex subunit SSRP1 OS=Homo sapiens OX=9606 GN=SSRP1 PE=1 SV=1 6.09 2236.5 - 1.09E+06 - - - -0.4749 - 1.47 0.178 - 248.3 1 2 0 -0.0005 8 0 0 0 5.08E+07 4.53E+07 - - - 1.5175 0.9685 221125_WJC_METTL3_EV_vs_WT_F03.10089.10089.2 0.229 20-Jul K.ELAAQLNEEAK.R sp|Q9Y5B9|SP16H_HUMAN 1 1214.6143 3.69 27041 10089 2 1214.609508 608.3144 FACT complex subunit SPT16 OS=Homo sapiens OX=9606 GN=SUPT16H PE=1 SV=1 4.25 2236.7 - 428596 - - - -3.9305 - 1.344 0.202 - 135.5 1 2 0 -0.0048 11 0 0 0 4.17E+07 1.13E+07 - - - 1.3313 0.9994 221125_WJC_METTL3_EV_vs_WT_F03.10094.10094.2 0.00333 14-Jul K.AFLDNGPK[136.11].T "sp|P78344|IF4G2_HUMAN,tr|H0Y3P2|H0Y3P2_HUMAN,tr|H0YCH5|H0YCH5_HUMAN,tr|D3DQV9|D3DQV9_HUMAN" 4 868.4534 1.3 27044 10094 2 868.45362 435.234 Eukaryotic translation initiation factor 4 gamma 2 OS=Homo sapiens OX=9606 GN=EIF4G2 PE=1 SV=1 5.88 2237.2 - 3.52E+06 - - - 0.2326 - 1.238 0.428 - 173.4 1 2 0 0.0002 8 0 0 0 1.94E+08 1.49E+08 - - - 2.846 0.8326 221125_WJC_METTL3_EV_vs_WT_F03.10097.10097.2 0.113 12-May R.SQMLLSR[166.11].R "sp|Q9BPW8|NIPS1_HUMAN,tr|C9JDV8|C9JDV8_HUMAN,tr|H7C2U6|H7C2U6_HUMAN" 3 843.4512 1.69 27047 10097 2 843.448276 422.7329 Protein NipSnap homolog 1 OS=Homo sapiens OX=9606 GN=NIPSNAP1 PE=1 SV=1 9.47 2237.4 - 993654 - - - -3.4584 - 1.325 0.01 - 103.5 2 2 0 -0.0029 7 0 0 0 1.57E+08 9.25E+07 - - - -0.1289 0.9981 221125_WJC_METTL3_EV_vs_WT_F03.10098.10098.2 0.0208 12-Jun K.VLVWHTR[166.11].T "sp|Q9NPZ5|B3GA2_HUMAN,sp|O94766|B3GA3_HUMAN,tr|A0A087WXU9|A0A087WXU9_HUMAN" 3 919.5267 1.57 27048 10098 2 919.525746 460.7706 Galactosylgalactosylxylosylprotein 3-beta-glucuronosyltransferase 2 OS=Homo sapiens OX=9606 GN=B3GAT2 PE=1 SV=2 9.73 2237.5 - 519968 - - - -1.0821 - 1.364 0.27 - 156.4 1 2 0 -0.001 7 0 0 0 2.23E+07 1.42E+07 - - - 2.0185 0.973 221125_WJC_METTL3_EV_vs_WT_F03.10099.10099.2 0.00228 20-Sep T.LATDMGTMQER.L "sp|P06576|ATPB_HUMAN,tr|F8W079|F8W079_HUMAN,tr|H0YI37|H0YI37_HUMAN,tr|F8W0P7|F8W0P7_HUMAN,tr|H0YH81|H0YH81_HUMAN" 5 1251.5588 4.25 27049 10099 2 1251.561285 626.7867 "ATP synthase subunit beta, mitochondrial OS=Homo sapiens OX=9606 GN=ATP5F1B PE=1 SV=3" 4.37 2237.6 - 517109 - - - 2.0199 - 1.97 0.437 - 246.3 1 1 0 0.0025 11 0 0 0 1.01E+07 2.37E+06 - - - 4.1021 0.9999 221125_WJC_METTL3_EV_vs_WT_F03.10100.10100.2 0.00536 18-Nov R.LDDC[160.03]GLTEAR.C "sp|P13489|RINI_HUMAN,tr|E9PLZ3|E9PLZ3_HUMAN,tr|E9PMA9|E9PMA9_HUMAN,tr|E9PMJ3|E9PMJ3_HUMAN,tr|E9PIK5|E9PIK5_HUMAN,tr|E9PIM9|E9PIM9_HUMAN,tr|E9PMN0|E9PMN0_HUMAN" 7 1148.5132 1.16 27050 10100 2 1148.51209 575.2639 Ribonuclease inhibitor OS=Homo sapiens OX=9606 GN=RNH1 PE=1 SV=2 4.03 2237.8 - 515816 - - - -0.956 - 2.448 0.487 - 326.8 1 2 0 -0.0011 10 0 0 0 3.79E+07 3.28E+07 - - - 5.1366 0.9998 221125_WJC_METTL3_EV_vs_WT_F03.10103.10103.2 2.42E-05 16-Sep R.LENEIQTYR.S "sp|P13645|K1C10_HUMAN,tr|A0A1B0GVI3|A0A1B0GVI3_HUMAN" 2 1164.5775 1302.5 27051 10103 2 1164.576904 583.296 "Keratin, type I cytoskeletal 10 OS=Homo sapiens OX=9606 GN=KRT10 PE=1 SV=6" 4.53 2238.2 - 2.02E+06 - - - -0.5135 - 2.308 0.407 - 346.2 1 2 0 -0.0006 9 0 0 0 1.15E+10 8.85E+06 - - - 4.4666 0.9995 221125_WJC_METTL3_EV_vs_WT_F03.10104.10104.2 0.00897 18-Oct R.IVTVVPQDTK[136.11].L "sp|O95163|ELP1_HUMAN,tr|A0A6Q8PFB7|A0A6Q8PFB7_HUMAN,tr|A0A6Q8PFH9|A0A6Q8PFH9_HUMAN,tr|A0A6Q8PH48|A0A6Q8PH48_HUMAN,tr|A0A6Q8PHC9|A0A6Q8PHC9_HUMAN,tr|A0A6Q8PHA0|A0A6Q8PHA0_HUMAN,tr|A0A6Q8PHI5|A0A6Q8PHI5_HUMAN,tr|A0A6Q8PF69|A0A6Q8PF69_HUMAN,tr|A0A6Q8PF66|A0A6Q8PF66_HUMAN,tr|A0A6Q8PGW3|A0A6Q8PGW3_HUMAN,tr|A0A6Q8PG86|A0A6Q8PG86_HUMAN,tr|A0A6Q8PGR0|A0A6Q8PGR0_HUMAN,tr|A0A6Q8PEX6|A0A6Q8PEX6_HUMAN,tr|F5H2T0|F5H2T0_HUMAN,tr|A0A6Q8PHF4|A0A6Q8PHF4_HUMAN,tr|A0A6Q8PFN8|A0A6Q8PFN8_HUMAN" 16 1106.6427 0.71 27052 10104 2 1106.641333 554.3286 Elongator complex protein 1 OS=Homo sapiens OX=9606 GN=ELP1 PE=1 SV=3 5.84 2238.3 - 1.33E+06 - - - -1.2127 - 1.724 0.365 - 297.5 1 2 0 -0.0013 10 0 0 0 2.23E+07 3.15E+07 - - - 3.2567 0.999 221125_WJC_METTL3_EV_vs_WT_F03.10106.10106.2 0.0771 14-Aug K.TTAQVLIR.F "sp|P15121|ALDR_HUMAN,sp|C9JRZ8|AK1BF_HUMAN" 2 900.5393 1.15 27054 10106 2 900.538464 451.2769 Aldo-keto reductase family 1 member B1 OS=Homo sapiens OX=9606 GN=AKR1B1 PE=1 SV=3 9.41 2238.5 - 1.01E+06 - - - -0.8906 - 1.691 0.252 - 237.2 1 2 0 -0.0008 8 0 0 0 5.76E+07 5.02E+07 - - - 2.4864 0.9999 221125_WJC_METTL3_EV_vs_WT_F03.10110.10110.2 0.00146 18-Oct R.LDDC[160.03]GLTEAR[166.11].C "sp|P13489|RINI_HUMAN,tr|E9PLZ3|E9PLZ3_HUMAN,tr|E9PMA9|E9PMA9_HUMAN,tr|E9PMJ3|E9PMJ3_HUMAN,tr|E9PIK5|E9PIK5_HUMAN,tr|E9PIM9|E9PIM9_HUMAN,tr|E9PMN0|E9PMN0_HUMAN" 7 1158.5215 1.15 27056 10110 2 1158.519812 580.268 Ribonuclease inhibitor OS=Homo sapiens OX=9606 GN=RNH1 PE=1 SV=2 4.03 2239 - 1.35E+06 - - - -1.4208 - 2.404 0.507 - 339.9 1 2 0 -0.0016 10 0 0 0 3.78E+07 3.28E+07 - - - 5.2335 0.9998 221125_WJC_METTL3_EV_vs_WT_F03.10111.10111.2 0.000308 24-Dec R.LVAAPVATANPAR[166.11].C "sp|Q9H9S5|FKRP_HUMAN,tr|M0R1M1|M0R1M1_HUMAN" 2 1259.7225 1.36 27057 10111 2 1259.722641 630.8685 Fukutin-related protein OS=Homo sapiens OX=9606 GN=FKRP PE=1 SV=1 9.75 2239.1 - 411521 - - - 0.0802 - 2.345 0.377 - 469.7 1 2 0 0.0001 13 0 0 0 6.95E+07 5.10E+07 - - - 4.0129 0.999 221125_WJC_METTL3_EV_vs_WT_F03.10114.10114.2 0.0104 16-Sep R.APLASQGWK[136.11].S sp|Q9NUL7|DDX28_HUMAN 1 964.5222 1.07 27058 10114 2 964.523683 483.2684 Probable ATP-dependent RNA helicase DDX28 OS=Homo sapiens OX=9606 GN=DDX28 PE=1 SV=2 8.8 2239.5 - 1.43E+06 - - - 1.5728 - 1.623 0.341 - 243.3 1 2 0 0.0015 9 0 0 0 9.90E+07 9.27E+07 - - - 2.9602 0.9946 221125_WJC_METTL3_EV_vs_WT_F03.10115.10115.2 0.287 12-Jul R.TQVELMR.K "sp|O43663|PRC1_HUMAN,tr|H0YM42|H0YM42_HUMAN" 2 875.4535 0.91 27059 10115 2 875.451445 438.734 Protein regulator of cytokinesis 1 OS=Homo sapiens OX=9606 GN=PRC1 PE=1 SV=2 5.66 2239.6 - 1.12E+06 - - - -2.3336 - 1.526 0.193 - 148.4 1 2 0 -0.002 7 0 0 0 4.17E+07 4.55E+07 - - - 1.805 0.999 221125_WJC_METTL3_EV_vs_WT_F03.10117.10117.2 0.282 16-Sep R.APLASQGWK.S sp|Q9NUL7|DDX28_HUMAN 1 956.508 1.07 27061 10117 2 956.507791 479.2613 Probable ATP-dependent RNA helicase DDX28 OS=Homo sapiens OX=9606 GN=DDX28 PE=1 SV=2 8.8 2239.7 - 1.19E+06 - - - -0.183 - 1.61 0.263 - 228.4 1 2 0 -0.0002 9 0 0 0 9.78E+07 9.17E+07 - - - 2.3612 0.998 221125_WJC_METTL3_EV_vs_WT_F03.10121.10121.2 0.000934 16-Oct K.NAGETLLQR.A "sp|Q6W2J9|BCOR_HUMAN,tr|H7BZ37|H7BZ37_HUMAN,tr|H7C2V9|H7C2V9_HUMAN,tr|H7C231|H7C231_HUMAN" 4 1000.5302 1.28 27063 10121 2 1000.52547 501.2724 BCL-6 corepressor OS=Homo sapiens OX=9606 GN=BCOR PE=1 SV=1 6 2240.2 - 4.17E+06 - - - -4.6855 - 1.942 0.512 - 366.7 1 2 0 -0.0047 9 0 0 0 9.44E+07 7.40E+07 - - - 4.7413 0.9979 221125_WJC_METTL3_EV_vs_WT_F03.10122.10122.2 0.0452 14-Aug K.TTAQVLIR[166.11].F "sp|P15121|ALDR_HUMAN,sp|C9JRZ8|AK1BF_HUMAN" 2 910.5475 1.15 27064 10122 2 910.549161 456.281 Aldo-keto reductase family 1 member B1 OS=Homo sapiens OX=9606 GN=AKR1B1 PE=1 SV=3 9.41 2240.3 - 2.56E+06 - - - 1.7846 - 1.621 0.247 - 263.5 1 2 0 0.0016 8 0 0 0 5.75E+07 5.02E+07 - - - 2.3217 0.9998 221125_WJC_METTL3_EV_vs_WT_F03.10127.10127.2 9.19E-05 18-Jul R.AVDDGVNTFK.V sp|P50990|TCPQ_HUMAN 1 1064.5138 0.41 27067 10127 2 1064.513208 533.2642 T-complex protein 1 subunit theta OS=Homo sapiens OX=9606 GN=CCT8 PE=1 SV=4 4.21 2240.8 - 3.10E+07 - - - -0.5928 - 1.693 0.532 - 107.9 1 2 0 -0.0006 10 0 0 0 1.27E+09 3.11E+09 - - - 4.4398 0.9999 221125_WJC_METTL3_EV_vs_WT_F03.10129.10129.2 9.03E-05 13/24 R.LVAAPVATANPAR.C "sp|Q9H9S5|FKRP_HUMAN,tr|M0R1M1|M0R1M1_HUMAN" 2 1249.7143 1.36 27068 10129 2 1249.71391 625.8644 Fukutin-related protein OS=Homo sapiens OX=9606 GN=FKRP PE=1 SV=1 9.75 2241 - 981869 - - - -0.2881 - 2.578 0.448 - 499.8 1 2 0 -0.0004 13 0 0 0 6.95E+07 5.10E+07 - - - 4.7804 0.9991 221125_WJC_METTL3_EV_vs_WT_F03.10130.10130.2 2.2 18-Dec R.ALASFNQEER[166.11].R "sp|Q5M9Q1|NKAPL_HUMAN,sp|Q8N5F7|NKAP_HUMAN,tr|A0A494C050|A0A494C050_HUMAN" 3 1173.5654 1.03 27069 10130 2 1173.566971 587.79 NKAP-like protein OS=Homo sapiens OX=9606 GN=NKAPL PE=1 SV=3 4.53 2241.2 - 520722 - - - 1.3634 - 1.956 0.264 - 674.6 1 2 0 0.0016 10 0 0 0 2.02E+07 1.95E+07 - - - 2.8631 0.9996 221125_WJC_METTL3_EV_vs_WT_F03.10137.10137.2 0.00238 16-Oct K.MVQFEENGR[166.11].K "sp|P49368|TCPG_HUMAN,tr|Q5SZW8|Q5SZW8_HUMAN,tr|E9PRC8|E9PRC8_HUMAN,tr|B4DUR8|B4DUR8_HUMAN,tr|E9PQ35|E9PQ35_HUMAN,tr|Q5SZX6|Q5SZX6_HUMAN" 6 1118.5054 0.16 27072 10137 2 1118.502693 560.26 T-complex protein 1 subunit gamma OS=Homo sapiens OX=9606 GN=CCT3 PE=1 SV=4 4.53 2242 - 1.24E+06 - - - -2.4318 - 1.866 0.491 - 431.9 1 2 0 -0.0027 9 0 0 0 7.00E+06 4.45E+07 - - - 4.4714 0.9998 221125_WJC_METTL3_EV_vs_WT_F03.10139.10139.2 0.00129 16-Oct R.AEYVIESAR.Q "sp|Q8NEM7|SP20H_HUMAN,tr|F6S7C4|F6S7C4_HUMAN,tr|C9JQS2|C9JQS2_HUMAN" 3 1036.5189 0.07 27074 10139 2 1036.519142 519.2667 Transcription factor SPT20 homolog OS=Homo sapiens OX=9606 GN=SUPT20H PE=1 SV=2 4.53 2242.2 - 3.11E+06 - - - 0.2094 - 2.059 0.396 - 483.3 1 2 0 0.0002 9 0 0 0 1.43E+08 1.97E+09 - - - 4.0552 0.999 221125_WJC_METTL3_EV_vs_WT_F03.10142.10142.2 0.0516 16-Aug R.NIVEAAAVR.D "sp|Q5JNZ5|RS26L_HUMAN,sp|P62854|RS26_HUMAN" 2 941.5294 0.98 27075 10142 2 941.529273 471.772 Putative 40S ribosomal protein S26-like 1 OS=Homo sapiens OX=9606 GN=RPS26P11 PE=5 SV=1 6 2242.6 - 1.30E+07 - - - -0.1667 - 1.648 0.252 - 215.7 1 2 0 -0.0002 9 0 0 0 3.53E+08 3.59E+08 - - - 2.3475 0.9999 221125_WJC_METTL3_EV_vs_WT_F03.10156.10156.2 0.00162 18-Nov R.GPLTVEETPR[166.11].V "sp|Q14676|MDC1_HUMAN,tr|A2AB05|A2AB05_HUMAN" 2 1107.58 1.35 27083 10156 2 1107.579707 554.7973 Mediator of DNA damage checkpoint protein 1 OS=Homo sapiens OX=9606 GN=MDC1 PE=1 SV=3 4.53 2244.2 - 805793 - - - -0.2266 - 2.53 0.431 - 564.1 1 2 0 -0.0003 10 0 0 0 4.63E+07 3.43E+07 - - - 4.8152 0.9996 221125_WJC_METTL3_EV_vs_WT_F03.10159.10159.2 0.00013 14-Sep R.TYDPEGFK[136.11].K "sp|Q8NFP7|NUD10_HUMAN,sp|Q96G61|NUD11_HUMAN" 2 963.4429 0.54 27086 10159 2 963.442864 482.7287 Diphosphoinositol polyphosphate phosphohydrolase 3-alpha OS=Homo sapiens OX=9606 GN=NUDT10 PE=1 SV=1 4.37 2244.4 - 2.13E+06 - - - -0.0509 - 1.328 0.464 - 261.7 1 2 0 0 8 0 0 0 4.54E+07 8.45E+07 - - - 3.3236 0.9999 221125_WJC_METTL3_EV_vs_WT_F03.10163.10163.2 7.98E-07 22-Nov K.GSFSDTGLGDGK.M "sp|Q9Y2W1|TR150_HUMAN,tr|A0A3B3ITZ9|A0A3B3ITZ9_HUMAN" 2 1139.5095 4.36 27088 10163 2 1139.508626 570.762 Thyroid hormone receptor-associated protein 3 OS=Homo sapiens OX=9606 GN=THRAP3 PE=1 SV=2 4.21 2244.8 - 1.00E+06 - - - -0.7512 - 2.249 0.605 - 250.5 1 2 0 -0.0009 12 0 0 0 4.61E+07 1.06E+07 - - - 5.6418 0.9942 221125_WJC_METTL3_EV_vs_WT_F03.10165.10165.2 0.0318 16-Nov R.LQSEVAELK[136.11].L "sp|P53990|IST1_HUMAN,tr|H3BMU1|H3BMU1_HUMAN,tr|H3BUI0|H3BUI0_HUMAN,tr|H3BQF7|H3BQF7_HUMAN,tr|F5GXM3|F5GXM3_HUMAN,tr|J3KR23|J3KR23_HUMAN" 6 1023.5692 1.36 27089 10165 2 1023.565618 512.7919 IST1 homolog OS=Homo sapiens OX=9606 GN=IST1 PE=1 SV=1 4.53 2245 - 611118 - - - -3.4761 - 2.03 0.184 - 274.8 1 2 0 -0.0036 9 0 0 0 2.78E+07 2.05E+07 - - - 2.4473 0.9891 221125_WJC_METTL3_EV_vs_WT_F03.10167.10167.2 0.0534 14-Aug K.SLTAEIDR.L "sp|P54136|SYRC_HUMAN,tr|E5RJM9|E5RJM9_HUMAN,tr|E5RH09|E5RH09_HUMAN" 3 903.4662 1.11 27091 10167 2 903.466285 452.7404 "Arginine--tRNA ligase, cytoplasmic OS=Homo sapiens OX=9606 GN=RARS1 PE=1 SV=2" 4.37 2245.2 - 4.53E+06 - - - 0.1372 - 1.65 0.002 - 253.8 1 2 0 0.0001 8 0 0 0 1.59E+08 1.43E+08 - - - 0.566 0.9976 221125_WJC_METTL3_EV_vs_WT_F03.10168.10168.2 0.00596 16-Aug K.TLGTGSFGR.V "sp|P22694|KAPCB_HUMAN,sp|P17612|KAPCA_HUMAN,tr|B1APF9|B1APF9_HUMAN,tr|B1APG0|B1APG0_HUMAN,tr|A0A087WVC4|A0A087WVC4_HUMAN,tr|B1APG2|B1APG2_HUMAN,tr|B1APF7|B1APF7_HUMAN,tr|Q15136|Q15136_HUMAN,tr|B1APF8|B1APF8_HUMAN,tr|B1APG1|B1APG1_HUMAN,tr|B1APG3|B1APG3_HUMAN,tr|K7ERP6|K7ERP6_HUMAN,tr|A0A0A0MS54|A0A0A0MS54_HUMAN" 13 894.4559 0.69 27092 10168 2 894.453388 448.2352 cAMP-dependent protein kinase catalytic subunit beta OS=Homo sapiens OX=9606 GN=PRKACB PE=1 SV=2 9.41 2245.2 - 2.70E+06 - - - -2.842 - 1.402 0.383 - 171.5 1 2 0 -0.0025 9 0 0 0 7.52E+07 1.09E+08 - - - 2.8466 0.9989 221125_WJC_METTL3_EV_vs_WT_F03.10169.10169.2 0.0069 16-Aug R.DFVEAPPPK[136.11].V "sp|Q6PKG0|LARP1_HUMAN,tr|A0A0B4J210|A0A0B4J210_HUMAN,tr|H0YBJ5|H0YBJ5_HUMAN,tr|H0YBM7|H0YBM7_HUMAN" 4 1006.5215 0.88 27093 10169 2 1006.519215 504.268 La-related protein 1 OS=Homo sapiens OX=9606 GN=LARP1 PE=1 SV=2 4.37 2245.3 - 953489 - - - -2.2672 - 1.545 0.393 - 236.5 1 2 0 -0.0023 9 0 0 0 2.84E+07 3.22E+07 - - - 3.2015 0.8415 221125_WJC_METTL3_EV_vs_WT_F03.10177.10177.2 1.55 14-May K.EFQSPGLR[166.11].G "sp|Q96KF7|SMIM8_HUMAN,tr|V9GYL2|V9GYL2_HUMAN,tr|V9GYF9|V9GYF9_HUMAN" 3 942.4799 1.13 27097 10177 2 942.477348 472.2472 Small integral membrane protein 8 OS=Homo sapiens OX=9606 GN=SMIM8 PE=1 SV=2 6.1 2246.3 - 5.16E+06 - - - -2.6547 - 0.916 0.104 - 93 1 2 0 -0.0025 8 0 0 0 1.95E+08 1.72E+08 - - - -0.4563 0.9898 221125_WJC_METTL3_EV_vs_WT_F03.10178.10178.2 0.331 14-Jun K.RALVILAK.G "sp|Q99497|PARK7_HUMAN,tr|K7ELW0|K7ELW0_HUMAN" 2 882.6015 2.24 27098 10178 2 882.59994 442.308 Parkinson disease protein 7 OS=Homo sapiens OX=9606 GN=PARK7 PE=1 SV=2 11 2246.4 - 1.38E+06 - - - -1.7358 - 1.24 0.179 - 122.5 1 2 0 -0.0015 8 0 0 0 4.02E+07 1.80E+07 - - - 1.0114 0.9998 221125_WJC_METTL3_EV_vs_WT_F03.10183.10183.2 0.000183 18-Oct R.GPLTVEETPR.V "sp|Q14676|MDC1_HUMAN,tr|A2AB05|A2AB05_HUMAN" 2 1097.5717 1.34 27100 10183 2 1097.570032 549.7931 Mediator of DNA damage checkpoint protein 1 OS=Homo sapiens OX=9606 GN=MDC1 PE=1 SV=3 4.53 2247.1 - 1.30E+06 - - - -1.5088 - 1.983 0.516 - 317.3 1 2 0 -0.0017 10 0 0 0 4.63E+07 3.45E+07 - - - 4.7626 0.9992 221125_WJC_METTL3_EV_vs_WT_F03.10184.10184.2 0.00259 14-Aug R.TYDPEGFK.K "sp|Q8NFP7|NUD10_HUMAN,sp|Q96G61|NUD11_HUMAN" 2 955.4287 0.53 27101 10184 2 955.428598 478.7216 Diphosphoinositol polyphosphate phosphohydrolase 3-alpha OS=Homo sapiens OX=9606 GN=NUDT10 PE=1 SV=1 4.37 2247.1 - 1.81E+06 - - - -0.1204 - 1.32 0.366 - 213.5 1 2 0 -0.0001 8 0 0 0 4.69E+07 8.80E+07 - - - 2.5816 0.995 221125_WJC_METTL3_EV_vs_WT_F03.10186.10186.2 0.214 20-Sep K.GAPGQPGTILR.T "sp|P51610|HCFC1_HUMAN,tr|A6NEM2|A6NEM2_HUMAN" 2 1065.5931 1.03 27103 10186 2 1065.590034 533.8038 Host cell factor 1 OS=Homo sapiens OX=9606 GN=HCFC1 PE=1 SV=2 9.75 2247.3 - 855206 - - - -2.8707 - 1.494 0.279 - 204.6 1 2 0 -0.0031 11 0 0 0 3.39E+07 3.30E+07 - - - 2.1868 0.9878 221125_WJC_METTL3_EV_vs_WT_F03.10189.10189.2 0.00215 14-Jul K.EFQSPGLR.G "sp|Q96KF7|SMIM8_HUMAN,tr|V9GYL2|V9GYL2_HUMAN,tr|V9GYF9|V9GYF9_HUMAN" 3 932.4716 1.17 27104 10189 2 932.470623 467.2431 Small integral membrane protein 8 OS=Homo sapiens OX=9606 GN=SMIM8 PE=1 SV=2 6.1 2247.7 - 4.43E+06 - - - -1.0263 - 1.434 0.066 - 194.2 1 2 0 -0.001 8 0 0 0 2.02E+08 1.73E+08 - - - 0.6153 0.9984 221125_WJC_METTL3_EV_vs_WT_F03.10191.10191.2 0.00333 16-Sep R.LQSEVAELK.L "sp|P53990|IST1_HUMAN,tr|H3BMU1|H3BMU1_HUMAN,tr|H3BUI0|H3BUI0_HUMAN,tr|H3BQF7|H3BQF7_HUMAN,tr|F5GXM3|F5GXM3_HUMAN,tr|J3KR23|J3KR23_HUMAN" 6 1015.555 1.36 27106 10191 2 1015.55549 508.7848 IST1 homolog OS=Homo sapiens OX=9606 GN=IST1 PE=1 SV=1 4.53 2248 - 1.15E+06 - - - 0.5061 - 1.838 0.166 - 187.5 1 2 0 0.0005 9 0 0 0 2.79E+07 2.05E+07 - - - 2.0279 0.9994 221125_WJC_METTL3_EV_vs_WT_F03.10196.10196.2 0.00449 16-Oct R.VPVDVAYQR[166.11].G "sp|P58107|EPIPL_HUMAN,sp|Q15149|PLEC_HUMAN,tr|A0A075B730|A0A075B730_HUMAN,tr|H0YDN1|H0YDN1_HUMAN" 4 1055.5639 1.72 27109 10196 2 1055.566037 528.7892 Epiplakin OS=Homo sapiens OX=9606 GN=EPPK1 PE=1 SV=3 5.81 2248.6 - 1.43E+06 - - - 2.0112 - 1.848 0.401 - 450 1 2 0 0.0021 9 0 0 0 1.01E+08 5.88E+07 - - - 3.7788 0.9996 221125_WJC_METTL3_EV_vs_WT_F03.10197.10197.2 0.00108 16-Sep R.YLASGSFDK.C "sp|Q9BZK7|TBL1R_HUMAN,sp|O60907|TBL1X_HUMAN,sp|Q9BQ87|TBL1Y_HUMAN,tr|A0A494C153|A0A494C153_HUMAN,tr|A0A804HJZ5|A0A804HJZ5_HUMAN,tr|A0A2R8YFW3|A0A2R8YFW3_HUMAN,tr|A0A0D9SF63|A0A0D9SF63_HUMAN" 7 986.4709 1.43 27110 10197 2 986.469985 494.2427 F-box-like\WD repeat-containing protein TBL1XR1 OS=Homo sapiens OX=9606 GN=TBL1XR1 PE=1 SV=1 5.83 2248.6 - 2.98E+06 - - - -0.9397 - 1.622 0.421 - 224.6 1 2 0 -0.0009 9 0 0 0 7.37E+07 5.14E+07 - - - 3.5495 0.8154 221125_WJC_METTL3_EV_vs_WT_F03.10203.10203.2 2.15 14-Jul K.ELEGVITK.A sp|O60763|USO1_HUMAN 1 887.4964 0.86 27114 10203 2 887.493639 444.7555 General vesicular transport factor p115 OS=Homo sapiens OX=9606 GN=USO1 PE=1 SV=2 4.53 2249.2 - 844415 - - - -3.1087 - 0.99 0.085 - 122.3 1 2 0 -0.0028 8 0 0 0 2.57E+07 3.00E+07 - - - -0.3624 0.9997 221125_WJC_METTL3_EV_vs_WT_F03.10204.10204.2 0.000845 14-Aug K.SC[160.03]QFVAVR.R sp|P07814|SYEP_HUMAN 1 965.4753 0.44 27115 10204 2 965.474747 483.7449 Bifunctional glutamate\proline--tRNA ligase OS=Homo sapiens OX=9606 GN=EPRS1 PE=1 SV=5 7.96 2249.3 - 2.39E+06 - - - -0.5583 - 1.609 0.454 - 342.8 1 2 0 -0.0005 8 0 0 0 4.46E+07 1.01E+08 - - - 3.8285 0.9982 221125_WJC_METTL3_EV_vs_WT_F03.10211.10211.2 0.106 16-Aug K.VTVAGLAGK[136.11].D "sp|Q99497|PARK7_HUMAN,tr|K7ELW0|K7ELW0_HUMAN" 2 822.5055 1.54 27120 10211 2 822.50416 412.26 Parkinson disease protein 7 OS=Homo sapiens OX=9606 GN=PARK7 PE=1 SV=2 8.72 2250.2 - 8.67E+06 - - - -1.572 - 1.745 0.219 - 214.3 1 2 0 -0.0013 9 0 0 0 5.63E+08 3.64E+08 - - - 2.2688 0.9998 221125_WJC_METTL3_EV_vs_WT_F03.10212.10212.2 0.000331 18-Nov R.VLTVINQTQK[136.11].E "sp|P42766|RL35_HUMAN,tr|F2Z388|F2Z388_HUMAN" 2 1150.6801 0.58 27121 10212 2 1150.680666 576.3473 60S ribosomal protein L35 OS=Homo sapiens OX=9606 GN=RPL35 PE=1 SV=2 8.72 2250.3 - 1.73E+06 - - - 0.4719 - 2.148 0.463 - 455.3 1 2 0 0.0005 10 0 0 0 3.64E+08 6.28E+08 - - - 4.5946 0.9997 221125_WJC_METTL3_EV_vs_WT_F03.10213.10213.2 5.07E-05 18-Sep K.LFADAEEEQR.R "sp|P46459|NSF_HUMAN,tr|I3L0N3|I3L0N3_HUMAN" 2 1206.5517 1.98 27122 10213 2 1206.554077 604.2831 Vesicle-fusing ATPase OS=Homo sapiens OX=9606 GN=NSF PE=1 SV=3 4 2250.4 - 714493 - - - 1.9858 - 1.8 0.552 - 321.8 1 2 0 0.0024 10 0 0 0 2.53E+07 1.28E+07 - - - 4.758 0.9997 221125_WJC_METTL3_EV_vs_WT_F03.10220.10220.2 0.0035 18-Sep R.VLTVINQTQK.E "sp|P42766|RL35_HUMAN,tr|F2Z388|F2Z388_HUMAN" 2 1142.6659 0.58 27127 10220 2 1142.665147 572.3402 60S ribosomal protein L35 OS=Homo sapiens OX=9606 GN=RPL35 PE=1 SV=2 8.72 2251.3 - 1.25E+06 - - - -0.6791 - 1.891 0.392 - 235.1 1 2 0 -0.0008 10 0 0 0 3.64E+08 6.28E+08 - - - 3.7144 0.996 221125_WJC_METTL3_EV_vs_WT_F03.10229.10229.2 0.237 12-Jul R.AYDIYSR.L "sp|Q16740|CLPP_HUMAN,tr|M0QYV5|M0QYV5_HUMAN" 2 886.4185 2.38 27134 10229 2 886.418195 444.2165 "ATP-dependent Clp protease proteolytic subunit, mitochondrial OS=Homo sapiens OX=9606 GN=CLPP PE=1 SV=1" 5.88 2252.3 - 933955 - - - -0.3238 - 1.3 0.188 - 205.9 1 2 0 -0.0003 7 0 0 0 2.03E+07 8.51E+06 - - - 1.2608 0.9905 221125_WJC_METTL3_EV_vs_WT_F03.10232.10232.2 0.984 14-Jun R.EASIC[160.03]ALR.Q "sp|O15381|NVL_HUMAN,tr|A0A087WV72|A0A087WV72_HUMAN" 2 918.4593 0.79 27137 10232 2 918.457926 460.2369 Nuclear valosin-containing protein-like OS=Homo sapiens OX=9606 GN=NVL PE=1 SV=1 6.09 2252.6 - 761598 - - - -1.4971 - 1.233 0.174 - 99.6 1 2 0 -0.0014 8 0 0 0 4.23E+07 5.37E+07 - - - 0.9574 0.9826 221125_WJC_METTL3_EV_vs_WT_F03.10233.10233.2 0.00942 20-Dec R.ALEEANAELER.K sp|Q7Z3Y7|K1C28_HUMAN 1 1243.6044 90.26 27138 10233 2 1243.596255 622.8095 "Keratin, type I cytoskeletal 28 OS=Homo sapiens OX=9606 GN=KRT28 PE=1 SV=2" 4.09 2252.7 - 418037 - - - -6.5857 - 2.096 0.341 - 587.2 1 2 0 -0.0082 11 0 0 0 6.25E+06 6.92E+04 - - - 3.559 0.9926 221125_WJC_METTL3_EV_vs_WT_F03.10234.10234.2 6.30E-05 20-Oct L.ADAVAVTMGPK[136.11].G "sp|P10809|CH60_HUMAN,tr|C9JL25|C9JL25_HUMAN,tr|A0A7I2V2X6|A0A7I2V2X6_HUMAN,tr|A0A7I2YQK6|A0A7I2YQK6_HUMAN,tr|A0A7I2V599|A0A7I2V599_HUMAN,tr|E7EXB4|E7EXB4_HUMAN,tr|C9JL19|C9JL19_HUMAN,tr|A0A7I2YQ71|A0A7I2YQ71_HUMAN,tr|C9J0S9|C9J0S9_HUMAN,tr|E7ESH4|E7ESH4_HUMAN,tr|A0A7I2V5M1|A0A7I2V5M1_HUMAN,tr|A0A7I2V5K3|A0A7I2V5K3_HUMAN,tr|A0A7I2V369|A0A7I2V369_HUMAN,tr|C9JCQ4|C9JCQ4_HUMAN" 14 1066.5572 0.93 27139 10234 2 1066.557025 534.2859 "60 kDa heat shock protein, mitochondrial OS=Homo sapiens OX=9606 GN=HSPD1 PE=1 SV=2" 5.88 2252.9 - 314020 - - - -0.1931 - 2.179 0.495 - 480.3 1 1 0 -0.0002 11 0 0 0 6.65E+07 7.14E+07 - - - 4.804 0.9992 221125_WJC_METTL3_EV_vs_WT_F03.10237.10237.2 0.069 16-Sep K.VTVAGLAGK.D "sp|Q99497|PARK7_HUMAN,tr|K7ELW0|K7ELW0_HUMAN" 2 814.4913 1.55 27140 10237 2 814.49099 408.2529 Parkinson disease protein 7 OS=Homo sapiens OX=9606 GN=PARK7 PE=1 SV=2 8.72 2253.3 - 1.30E+07 - - - -0.3229 - 1.816 0.243 - 206.2 1 2 0 -0.0003 9 0 0 0 5.63E+08 3.64E+08 - - - 2.5618 0.7808 221125_WJC_METTL3_EV_vs_WT_F03.10240.10240.2 0.491 14-Aug K.NLSPSFSR.P "sp|Q1ED39|KNOP1_HUMAN,tr|H3BNU8|H3BNU8_HUMAN" 2 906.4559 2.01 27143 10240 2 906.456563 454.2352 Lysine-rich nucleolar protein 1 OS=Homo sapiens OX=9606 GN=KNOP1 PE=1 SV=1 9.75 2253.4 - 968665 - - - 0.6983 - 1.375 0.171 - 227.3 1 1 0 0.0006 8 0 0 0 2.96E+07 1.47E+07 - - - 1.2642 0.9988 221125_WJC_METTL3_EV_vs_WT_F03.10241.10241.2 0.0123 12-Jul R.DYDVYAR.R "sp|Q9Y5K3|PCY1B_HUMAN,sp|P49585|PCY1A_HUMAN,tr|H7C1T3|H7C1T3_HUMAN,tr|C9J050|C9J050_HUMAN,tr|C9JEJ2|C9JEJ2_HUMAN,tr|H7BZN1|H7BZN1_HUMAN" 6 900.3977 1.49 27144 10241 2 900.398486 451.2061 Choline-phosphate cytidylyltransferase B OS=Homo sapiens OX=9606 GN=PCYT1B PE=1 SV=1 4.21 2253.5 - 622342 - - - 0.8207 - 1.267 0.347 - 222.2 1 2 0 0.0007 7 0 0 0 2.03E+07 1.36E+07 - - - 2.3536 0.9803 221125_WJC_METTL3_EV_vs_WT_F03.10247.10247.2 0.163 14-Jun K.LVIEEAER[166.11].S sp|P50991|TCPD_HUMAN 1 967.5214 0.36 27148 10247 2 967.521642 484.768 T-complex protein 1 subunit delta OS=Homo sapiens OX=9606 GN=CCT4 PE=1 SV=4 4.25 2254.2 - 2.67E+06 - - - 0.2698 - 1.379 0.024 - 140.8 1 2 0 0.0003 8 0 0 0 9.64E+07 2.71E+08 - - - 0.1874 0.9976 221125_WJC_METTL3_EV_vs_WT_F03.10248.10248.2 0.159 14-Sep R.TAALEQLR.E sp|Q8IVW6|ARI3B_HUMAN 1 900.5029 0.96 27149 10248 2 900.502331 451.2587 AT-rich interactive domain-containing protein 3B OS=Homo sapiens OX=9606 GN=ARID3B PE=1 SV=2 5.66 2254.2 - 795617 - - - -0.6108 - 1.513 0.189 - 361.7 1 2 0 -0.0006 8 0 0 0 6.79E+07 7.10E+07 - - - 1.6857 0.9945 221125_WJC_METTL3_EV_vs_WT_F03.10249.10249.2 0.00617 26-Jun R.SSFYPDGGDQETAK.T "sp|Q9NYF8|BCLF1_HUMAN,tr|H0YF00|H0YF00_HUMAN,tr|E9PKI6|E9PKI6_HUMAN,tr|A0A1W2PQ43|A0A1W2PQ43_HUMAN,tr|E9PK91|E9PK91_HUMAN,tr|E9PJA7|E9PJA7_HUMAN,tr|E9PK09|E9PK09_HUMAN,tr|E9PQN2|E9PQN2_HUMAN" 8 1500.6369 3.15 27150 10249 2 1500.640442 751.3257 Bcl-2-associated transcription factor 1 OS=Homo sapiens OX=9606 GN=BCLAF1 PE=1 SV=2 4.03 2254.4 - 109169 - - - 2.3817 - 0.87 0.428 - 61.5 1 2 0 0.0036 14 0 0 0 8.48E+06 2.69E+06 - - - 1.8516 0.9992 221125_WJC_METTL3_EV_vs_WT_F03.10253.10253.2 0.000164 20-Oct R.LLQDSLGGNAK[136.11].T "sp|O14782|KIF3C_HUMAN,sp|O15066|KIF3B_HUMAN,tr|F8WER6|F8WER6_HUMAN,tr|F8WAR6|F8WAR6_HUMAN" 4 1122.6124 8.12 27152 10253 2 1122.612155 562.3135 Kinesin-like protein KIF3C OS=Homo sapiens OX=9606 GN=KIF3C PE=1 SV=3 5.84 2254.9 - 273213 - - - -0.2521 - 1.635 0.302 - 229.8 1 2 0 -0.0003 11 0 0 0 7.21E+07 8.88E+06 - - - 2.6015 0.998 221125_WJC_METTL3_EV_vs_WT_F03.10254.10254.2 0.267 14-Oct R.TAALEQLR[166.11].E sp|Q8IVW6|ARI3B_HUMAN 1 910.5112 1.2 27153 10254 2 910.511498 456.2629 AT-rich interactive domain-containing protein 3B OS=Homo sapiens OX=9606 GN=ARID3B PE=1 SV=2 5.66 2255 - 1.08E+06 - - - 0.3811 - 1.751 0.147 - 491.1 1 2 0 0.0003 8 0 0 0 6.77E+07 5.66E+07 - - - 1.8161 0.9991 221125_WJC_METTL3_EV_vs_WT_F03.10258.10258.2 0.0022 16-Aug R.FFVSSSQGR.S "sp|P35613|BASI_HUMAN,tr|A0A7P0T8A7|A0A7P0T8A7_HUMAN,tr|A0A087WUV8|A0A087WUV8_HUMAN,tr|A0A7P0TA85|A0A7P0TA85_HUMAN,tr|A0A7P0TB04|A0A7P0TB04_HUMAN,tr|R4GMX5|R4GMX5_HUMAN,tr|I3L192|I3L192_HUMAN" 7 1013.493 1.01 27156 10258 2 1013.490631 507.7538 Basigin OS=Homo sapiens OX=9606 GN=BSG PE=1 SV=2 9.75 2255.4 - 8.32E+06 - - - -2.3809 - 1.705 0.393 - 186.1 1 2 0 -0.0024 9 0 0 0 2.94E+08 2.92E+08 - - - 3.4866 0.8333 221125_WJC_METTL3_EV_vs_WT_F03.10261.10261.3 0.1 Dec-36 R.ALVVEMSR[166.11]PR[166.11].P "sp|Q96PK6|RBM14_HUMAN,tr|B8ZZ74|B8ZZ74_HUMAN,tr|F8WDX3|F8WDX3_HUMAN,tr|A0A0A0MSL8|A0A0A0MSL8_HUMAN,tr|A0A0A6YYI9|A0A0A6YYI9_HUMAN" 5 1176.6552 1.55 27157 10261 3 1176.654483 393.2257 RNA-binding protein 14 OS=Homo sapiens OX=9606 GN=RBM14 PE=1 SV=2 9.64 2255.8 - 2.97E+06 - - - -0.6119 - 1.899 0.22 - 248.1 1 1 0 -0.0007 10 0 0 0 2.90E+08 1.87E+08 - - - 2.8655 0.9925 221125_WJC_METTL3_EV_vs_WT_F03.10263.10263.3 0.0885 Oct-36 K.VTLLEGDHVR[166.11].F "sp|O75534|CSDE1_HUMAN,tr|E9PLT0|E9PLT0_HUMAN" 2 1147.6225 0.39 27159 10263 3 1147.623662 383.5481 Cold shock domain-containing protein E1 OS=Homo sapiens OX=9606 GN=CSDE1 PE=1 SV=2 5.32 2255.9 - 987123 - - - 1.0195 - 1.575 0.196 - 126.7 1 2 0 0.0012 10 0 0 0 3.61E+07 9.22E+07 - - - 2.0515 0.9996 221125_WJC_METTL3_EV_vs_WT_F03.10268.10268.2 0.016 14-May K.SVALYDC[160.03]R.S "sp|Q13610|PWP1_HUMAN,tr|B4DJV5|B4DJV5_HUMAN" 2 982.4542 1.08 27162 10268 2 982.454812 492.2344 Periodic tryptophan protein 1 homolog OS=Homo sapiens OX=9606 GN=PWP1 PE=1 SV=1 5.55 2256.5 - 1.12E+06 - - - 0.6066 - 1.533 0.411 - 104.7 1 2 0 0.0006 8 0 0 0 3.92E+07 3.63E+07 - - - 3.365 0.9862 221125_WJC_METTL3_EV_vs_WT_F03.10270.10270.2 0.396 26-Jun R.SSFYPDGGDQETAK[136.11].T "sp|Q9NYF8|BCLF1_HUMAN,tr|H0YF00|H0YF00_HUMAN,tr|E9PKI6|E9PKI6_HUMAN,tr|A0A1W2PQ43|A0A1W2PQ43_HUMAN,tr|E9PK91|E9PK91_HUMAN,tr|E9PJA7|E9PJA7_HUMAN,tr|E9PK09|E9PK09_HUMAN,tr|E9PQN2|E9PQN2_HUMAN" 8 1508.6511 3.15 27164 10270 2 1508.652573 755.3328 Bcl-2-associated transcription factor 1 OS=Homo sapiens OX=9606 GN=BCLAF1 PE=1 SV=2 4.03 2256.7 - 125044 - - - 0.9976 - 0.998 0.21 - 41.5 1 2 0 0.0015 14 0 0 0 8.48E+06 2.69E+06 - - - 0.5866 0.9996 221125_WJC_METTL3_EV_vs_WT_F03.10273.10273.2 0.0113 14-Jul K.SVALYDC[160.03]R[166.11].S "sp|Q13610|PWP1_HUMAN,tr|B4DJV5|B4DJV5_HUMAN" 2 992.4625 1.05 27165 10273 2 992.462094 497.2385 Periodic tryptophan protein 1 homolog OS=Homo sapiens OX=9606 GN=PWP1 PE=1 SV=1 5.55 2257.1 - 1.46E+06 - - - -0.395 - 1.72 0.359 - 210.6 1 2 0 -0.0004 8 0 0 0 3.92E+07 3.73E+07 - - - 3.3281 0.9889 221125_WJC_METTL3_EV_vs_WT_F03.10275.10275.2 0.212 12-Jun K.EQYLGYR.K "sp|Q9BVL2|NUP58_HUMAN,tr|H7BYF2|H7BYF2_HUMAN,tr|Q5JRG1|Q5JRG1_HUMAN" 3 927.445 1.61 27167 10275 2 927.444866 464.7298 Nucleoporin p58\p45 OS=Homo sapiens OX=9606 GN=NUP58 PE=1 SV=1 6.1 2257.3 - 1.75E+06 - - - -0.1779 - 1.176 0.134 - 157.4 1 2 0 -0.0002 7 0 0 0 4.63E+07 2.88E+07 - - - 0.5444 0.9984 221125_WJC_METTL3_EV_vs_WT_F03.10276.10276.2 0.0214 20-Sep R.LLQDSLGGNAK.T "sp|O14782|KIF3C_HUMAN,sp|O15066|KIF3B_HUMAN,tr|F8WER6|F8WER6_HUMAN,tr|F8WAR6|F8WAR6_HUMAN" 4 1114.5982 8.97 27168 10276 2 1114.600033 558.3064 Kinesin-like protein KIF3C OS=Homo sapiens OX=9606 GN=KIF3C PE=1 SV=3 5.84 2257.4 - 423784 - - - 1.6104 - 1.948 0.225 - 137.7 1 2 0 0.0018 11 0 0 0 1.25E+08 1.40E+07 - - - 2.5061 0.9903 221125_WJC_METTL3_EV_vs_WT_F03.10281.10281.2 0.761 12-Jul K.TLWNGQK[136.11].L sp|Q01518|CAP1_HUMAN 1 853.4538 1.96 27171 10281 2 853.45524 427.7342 Adenylyl cyclase-associated protein 1 OS=Homo sapiens OX=9606 GN=CAP1 PE=1 SV=5 8.41 2258 - 728879 - - - 1.7435 - 1.23 0.192 - 133.1 1 2 0 0.0015 7 0 0 0 3.13E+07 1.60E+07 - - - 1.1146 0.9998 221125_WJC_METTL3_EV_vs_WT_F03.10283.10283.2 0.0155 16-Sep R.VPVDVAYQR.G "sp|P58107|EPIPL_HUMAN,sp|Q15149|PLEC_HUMAN,tr|A0A075B730|A0A075B730_HUMAN,tr|H0YDN1|H0YDN1_HUMAN" 4 1045.5556 1.72 27172 10283 2 1045.55672 523.7851 Epiplakin OS=Homo sapiens OX=9606 GN=EPPK1 PE=1 SV=3 5.81 2258.2 - 1.35E+06 - - - 1.0291 - 1.948 0.483 - 364.7 1 2 0 0.0011 9 0 0 0 1.01E+08 5.87E+07 - - - 4.5372 0.9987 221125_WJC_METTL3_EV_vs_WT_F03.10289.10289.2 0.626 12-Aug R.LAADDFR.T "sp|Q04695|K1C17_HUMAN,sp|P13645|K1C10_HUMAN,sp|O76015|KRT38_HUMAN,sp|Q2M2I5|K1C24_HUMAN,sp|Q15323|K1H1_HUMAN,sp|P02533|K1C14_HUMAN,sp|P05783|K1C18_HUMAN,sp|P08727|K1C19_HUMAN,sp|P08779|K1C16_HUMAN,sp|Q7Z3Y7|K1C28_HUMAN,sp|Q14532|K1H2_HUMAN,sp|P19012|K1C15_HUMAN,sp|O76013|KRT36_HUMAN,sp|Q14525|KT33B_HUMAN,sp|Q92764|KRT35_HUMAN,sp|O76014|KRT37_HUMAN,sp|P13646|K1C13_HUMAN,tr|F8VZY9|F8VZY9_HUMAN,tr|K7EPJ9|K7EPJ9_HUMAN,tr|C9JM50|C9JM50_HUMAN,tr|A0A1B0GVI3|A0A1B0GVI3_HUMAN,tr|K7EMD9|K7EMD9_HUMAN,tr|F5GWP8|F5GWP8_HUMAN,tr|K7ERE3|K7ERE3_HUMAN,tr|C4AM86|C4AM86_HUMAN" 25 806.3923 1970.39 27176 10289 2 806.39273 404.2034 "Keratin, type I cytoskeletal 17 OS=Homo sapiens OX=9606 GN=KRT17 PE=1 SV=2" 4.21 2258.8 - 3.79E+07 - - - 0.5742 - 1.517 0.253 - 275.6 1 2 0 0.0005 7 0 0 0 3.72E+09 1.89E+06 - - - 2.23 0.9999 221125_WJC_METTL3_EV_vs_WT_F03.10290.10290.3 0.000499 15/36 K.VTLLEGDHVR.F "sp|O75534|CSDE1_HUMAN,tr|E9PLT0|E9PLT0_HUMAN" 2 1137.6142 0.36 27177 10290 3 1137.615064 380.212 Cold shock domain-containing protein E1 OS=Homo sapiens OX=9606 GN=CSDE1 PE=1 SV=2 5.32 2258.9 - 954501 - - - 0.7401 - 2.15 0.45 - 337.2 1 2 0 0.0008 10 0 0 0 3.34E+07 9.17E+07 - - - 5.7923 0.9994 221125_WJC_METTL3_EV_vs_WT_F03.10298.10298.2 5.28E-05 20-Dec K.VTADVINAAEK[136.11].L "sp|O43175|SERA_HUMAN,tr|A0A2C9F2M7|A0A2C9F2M7_HUMAN,tr|A0A286YFB2|A0A286YFB2_HUMAN,tr|A0A286YF34|A0A286YF34_HUMAN,tr|A0A286YFC8|A0A286YFC8_HUMAN,tr|A0A286YF22|A0A286YF22_HUMAN,tr|A0A286YFL2|A0A286YFL2_HUMAN,tr|A0A286YFA2|A0A286YFA2_HUMAN,tr|A0A286YFM8|A0A286YFM8_HUMAN,tr|A0A286YER3|A0A286YER3_HUMAN" 10 1137.6121 1.4 27181 10298 2 1137.615276 569.8133 D-3-phosphoglycerate dehydrogenase OS=Homo sapiens OX=9606 GN=PHGDH PE=1 SV=4 4.37 2259.8 - 1.17E+06 - - - 2.7892 - 2.142 0.449 - 381.4 1 2 0 0.0032 11 0 0 0 2.65E+08 1.90E+08 - - - 4.417 0.9538 221125_WJC_METTL3_EV_vs_WT_F03.10304.10304.2 2.31 12-Jun R.GANQWIK[136.11].F "sp|P08559|ODPA_HUMAN,tr|Q5JPU3|Q5JPU3_HUMAN" 2 823.4432 0.21 27185 10304 2 823.442688 412.7289 "Pyruvate dehydrogenase E1 component subunit alpha, somatic form, mitochondrial OS=Homo sapiens OX=9606 GN=PDHA1 PE=1 SV=3" 8.75 2260.5 - 981842 - - - -0.606 - 1.062 0.056 - 147.7 1 2 0 -0.0005 7 0 0 0 6.09E+06 2.96E+07 - - - -0.3549 0.9989 221125_WJC_METTL3_EV_vs_WT_F03.10307.10307.2 0.00244 14-Jul R.GFPSVDSR.G tr|A0A3B3ITJ4|A0A3B3ITJ4_HUMAN 1 863.4137 0.81 27187 10307 2 863.41273 432.7141 Heterogeneous nuclear ribonucleoprotein L (Fragment) OS=Homo sapiens OX=9606 GN=HNRNPL PE=1 SV=1 5.84 2260.8 - 596188 - - - -1.1594 - 1.376 0.341 - 201.5 1 2 0 -0.001 8 0 0 0 2.87E+07 3.55E+07 - - - 2.5219 0.9999 221125_WJC_METTL3_EV_vs_WT_F03.10308.10308.2 7.54E-05 20-Nov K.VTADVINAAEK.L "sp|O43175|SERA_HUMAN,tr|A0A2C9F2M7|A0A2C9F2M7_HUMAN,tr|A0A286YFB2|A0A286YFB2_HUMAN,tr|A0A286YF34|A0A286YF34_HUMAN,tr|A0A286YFC8|A0A286YFC8_HUMAN,tr|A0A286YF22|A0A286YF22_HUMAN,tr|A0A286YFL2|A0A286YFL2_HUMAN,tr|A0A286YFA2|A0A286YFA2_HUMAN,tr|A0A286YFM8|A0A286YFM8_HUMAN,tr|A0A286YER3|A0A286YER3_HUMAN" 10 1129.5979 1.4 27188 10308 2 1129.598561 565.8062 D-3-phosphoglycerate dehydrogenase OS=Homo sapiens OX=9606 GN=PHGDH PE=1 SV=4 4.37 2260.9 - 2.42E+06 - - - 0.5825 - 2.598 0.464 - 411.2 1 2 0 0.0007 11 0 0 0 2.65E+08 1.90E+08 - - - 5.0507 0.8331 221125_WJC_METTL3_EV_vs_WT_F03.10313.10313.2 6.11 16-May K.ETGVPIAGR[166.11].H "sp|P11586|C1TC_HUMAN,tr|F5H2F4|F5H2F4_HUMAN,tr|V9GZ78|V9GZ78_HUMAN,tr|V9GYY3|V9GYY3_HUMAN" 4 908.4955 0.31 27191 10313 2 908.496756 455.255 "C-1-tetrahydrofolate synthase, cytoplasmic OS=Homo sapiens OX=9606 GN=MTHFD1 PE=1 SV=4" 6.1 2261.5 - 1.53E+06 - - - 1.3814 - 1.089 0.026 - 77.6 10 2 0 0.0013 9 0 0 0 2.53E+07 8.07E+07 - - - -0.9674 0.9996 221125_WJC_METTL3_EV_vs_WT_F03.10314.10314.2 0.00127 18-Aug K.LYVANVGTNR.A sp|Q15750|TAB1_HUMAN 1 1105.588 0.24 27192 10314 2 1105.586655 553.8013 TGF-beta-activated kinase 1 and MAP3K7-binding protein 1 OS=Homo sapiens OX=9606 GN=TAB1 PE=1 SV=1 8.75 2261.6 - 852688 - - - -1.2229 - 1.812 0.406 - 243.4 1 2 0 -0.0014 10 0 0 0 1.73E+07 7.29E+07 - - - 3.6985 0.9911 221125_WJC_METTL3_EV_vs_WT_F03.10315.10315.3 0.000154 Dec-36 R.ALVVEMSRPR.P "sp|Q96PK6|RBM14_HUMAN,tr|B8ZZ74|B8ZZ74_HUMAN,tr|F8WDX3|F8WDX3_HUMAN,tr|A0A0A0MSL8|A0A0A0MSL8_HUMAN,tr|A0A0A6YYI9|A0A0A6YYI9_HUMAN" 5 1156.6387 1.56 27193 10315 3 1156.639136 386.5535 RNA-binding protein 14 OS=Homo sapiens OX=9606 GN=RBM14 PE=1 SV=2 9.64 2261.7 - 1.08E+07 - - - 0.4089 - 2.511 0.369 - 271.8 1 1 0 0.0005 10 0 0 0 2.90E+08 1.85E+08 - - - 5.3426 0.9987 221125_WJC_METTL3_EV_vs_WT_F03.10320.10320.2 0.0103 16-Aug K.ATVSAPFGK[136.11].F "sp|Q15149|PLEC_HUMAN,tr|H0YDN1|H0YDN1_HUMAN" 2 884.4847 0.65 27196 10320 2 884.486838 443.2496 Plectin OS=Homo sapiens OX=9606 GN=PLEC PE=1 SV=3 8.8 2262.3 - 1.60E+06 - - - 2.3969 - 1.586 0.384 - 176.9 1 2 0 0.0021 9 0 0 0 4.83E+07 7.45E+07 - - - 3.2109 0.9998 221125_WJC_METTL3_EV_vs_WT_F03.10323.10323.2 4.48E-08 20-Nov K.VLETAEDIQER.R "sp|Q13813|SPTN1_HUMAN,tr|A0A0D9SFF6|A0A0D9SFF6_HUMAN,tr|A0A0D9SF54|A0A0D9SF54_HUMAN,tr|A0A0D9SGF6|A0A0D9SGF6_HUMAN,tr|A0A1B0GTB7|A0A1B0GTB7_HUMAN" 5 1301.6463 1.31 27197 10323 2 1301.643565 651.8304 "Spectrin alpha chain, non-erythrocytic 1 OS=Homo sapiens OX=9606 GN=SPTAN1 PE=1 SV=3" 4 2262.7 - 261304 - - - -2.1089 - 2.199 0.581 - 424.6 1 2 0 -0.0027 11 0 0 0 5.12E+07 3.91E+07 - - - 5.4631 0.9976 221125_WJC_METTL3_EV_vs_WT_F03.10325.10325.2 0.173 14-Jun R.IGVLDEGK.M "sp|P46781|RS9_HUMAN,tr|C9JM19|C9JM19_HUMAN,tr|B5MCT8|B5MCT8_HUMAN" 3 829.4545 1.15 27198 10325 2 829.453444 415.7345 40S ribosomal protein S9 OS=Homo sapiens OX=9606 GN=RPS9 PE=1 SV=3 4.37 2262.9 - 2.23E+06 - - - -1.3129 - 1.547 0.211 - 104.3 1 2 0 -0.0011 8 0 0 0 5.57E+07 4.83E+07 - - - 1.915 0.9995 221125_WJC_METTL3_EV_vs_WT_F03.10327.10327.2 0.00453 16-Sep R.SSLLAVSNK.Y "sp|P35658|NU214_HUMAN,tr|A0A494BZU9|A0A494BZU9_HUMAN,tr|A0A494C1F2|A0A494C1F2_HUMAN" 3 917.5182 2.44 27200 10327 2 917.518284 459.7664 Nuclear pore complex protein Nup214 OS=Homo sapiens OX=9606 GN=NUP214 PE=1 SV=2 8.47 2263 - 1.10E+06 - - - 0.0959 - 1.68 0.34 - 239.4 1 2 0 0.0001 9 0 0 0 1.05E+08 4.30E+07 - - - 3.0531 0.9802 221125_WJC_METTL3_EV_vs_WT_F03.10329.10329.2 0.0172 16-Jul R.SLSYSPVER[166.11].R "sp|Q9UQ35|SRRM2_HUMAN,tr|I3L4U6|I3L4U6_HUMAN" 2 1046.5272 0.25 27202 10329 2 1046.521818 524.2709 Serine\arginine repetitive matrix protein 2 OS=Homo sapiens OX=9606 GN=SRRM2 PE=1 SV=2 5.72 2263.1 - 519569 - - - -5.1379 - 1.374 0.333 - 173.4 1 2 0 -0.0054 9 0 0 0 3.02E+06 1.19E+07 - - - 2.418 0.9812 221125_WJC_METTL3_EV_vs_WT_F03.10331.10331.2 0.378 12-Jul R.HLQLAIR.N "sp|P16104|H2AX_HUMAN,sp|Q9BTM1|H2AJ_HUMAN,sp|Q93077|H2A1C_HUMAN,sp|Q99878|H2A1J_HUMAN,sp|Q16777|H2A2C_HUMAN,sp|Q96QV6|H2A1A_HUMAN,sp|P0C0S5|H2AZ_HUMAN,sp|P04908|H2A1B_HUMAN,sp|P20671|H2A1D_HUMAN,sp|P0C0S8|H2A1_HUMAN,sp|Q6FI13|H2A2A_HUMAN,sp|Q96KK5|H2A1H_HUMAN,sp|Q71UI9|H2AV_HUMAN,sp|Q7L7L0|H2A3_HUMAN,tr|C9J386|C9J386_HUMAN,tr|A0A0U1RR32|A0A0U1RR32_HUMAN,tr|A0A0U1RRH7|A0A0U1RRH7_HUMAN,tr|A0A3B3IS11|A0A3B3IS11_HUMAN,tr|H0YFX9|H0YFX9_HUMAN,tr|C9J0D1|C9J0D1_HUMAN,tr|A0A494C189|A0A494C189_HUMAN" 21 849.5185 1.14 27203 10331 2 849.517435 425.7665 Histone H2AX OS=Homo sapiens OX=9606 GN=H2AX PE=1 SV=2 9.76 2263.4 - 637487 - - - -1.2195 - 1.283 0.075 - 142.2 1 2 0 -0.001 7 0 0 0 5.75E+09 5.04E+09 - - - 0.3842 0.9762 221125_WJC_METTL3_EV_vs_WT_F03.10333.10333.2 0.755 14-Sep R.IGVLDEGK[136.11].M "sp|P46781|RS9_HUMAN,tr|C9JM19|C9JM19_HUMAN,tr|B5MCT8|B5MCT8_HUMAN" 3 837.4687 1.32 27204 10333 2 837.466 419.7416 40S ribosomal protein S9 OS=Homo sapiens OX=9606 GN=RPS9 PE=1 SV=3 4.37 2263.6 - 1.65E+06 - - - -3.2634 - 1.585 0.102 - 181.2 1 2 0 -0.0027 8 0 0 0 6.58E+07 5.00E+07 - - - 1.1826 0.9966 221125_WJC_METTL3_EV_vs_WT_F03.10334.10334.2 0.125 16-Jun R.LVPSVNGVR.R "sp|P11586|C1TC_HUMAN,tr|F5H2F4|F5H2F4_HUMAN,tr|V9GZ78|V9GZ78_HUMAN,tr|V9GYY3|V9GYY3_HUMAN,tr|A0A494C1T2|A0A494C1T2_HUMAN" 5 939.5502 2.21 27205 10334 2 939.550651 470.7824 "C-1-tetrahydrofolate synthase, cytoplasmic OS=Homo sapiens OX=9606 GN=MTHFD1 PE=1 SV=4" 9.75 2263.7 - 1.15E+06 - - - 0.5173 - 1.342 0.248 - 57.5 4 2 0 0.0005 9 0 0 0 3.58E+07 1.62E+07 - - - 1.4547 0.9998 221125_WJC_METTL3_EV_vs_WT_F03.10335.10335.2 0.000107 16-Aug R.ELISDNQYR[166.11].L sp|P25205|MCM3_HUMAN 1 1146.5545 0.48 27206 10335 2 1146.554464 574.2845 DNA replication licensing factor MCM3 OS=Homo sapiens OX=9606 GN=MCM3 PE=1 SV=3 4.37 2263.7 - 3.20E+06 - - - -0.007 - 1.898 0.417 - 259 1 2 0 0 9 0 0 0 4.19E+07 8.65E+07 - - - 3.9748 0.9986 221125_WJC_METTL3_EV_vs_WT_F03.10336.10336.2 0.0237 14-Jul K.YFEGVSPK.S sp|P78527|PRKDC_HUMAN 1 925.4545 0.58 27207 10336 2 925.4551 463.7345 DNA-dependent protein kinase catalytic subunit OS=Homo sapiens OX=9606 GN=PRKDC PE=1 SV=3 6 2263.8 - 1.09E+06 - - - 0.6127 - 1.236 0.338 - 136.6 1 2 0 0.0006 8 0 0 0 3.05E+07 5.22E+07 - - - 2.1763 0.9998 221125_WJC_METTL3_EV_vs_WT_F03.10337.10337.2 4.96E-05 20-Dec K.VLETAEDIQER[166.11].R "sp|Q13813|SPTN1_HUMAN,tr|A0A0D9SFF6|A0A0D9SFF6_HUMAN,tr|A0A0D9SF54|A0A0D9SF54_HUMAN,tr|A0A0D9SGF6|A0A0D9SGF6_HUMAN,tr|A0A1B0GTB7|A0A1B0GTB7_HUMAN" 5 1311.6546 1.31 27208 10337 2 1311.655593 656.8346 "Spectrin alpha chain, non-erythrocytic 1 OS=Homo sapiens OX=9606 GN=SPTAN1 PE=1 SV=3" 4 2263.9 - 419906 - - - 0.7723 - 2.301 0.438 - 563.1 1 2 0 0.001 11 0 0 0 5.12E+07 3.91E+07 - - - 4.5301 0.9999 221125_WJC_METTL3_EV_vs_WT_F03.10338.10338.2 1.36E-08 Nov-32 R.GSGGLGGAC[160.03]GGAGFGSR.S "sp|P48668|K2C6C_HUMAN,sp|P04259|K2C6B_HUMAN,sp|P02538|K2C6A_HUMAN" 3 1423.6263 999 27209 10338 2 1423.62739 712.8204 "Keratin, type II cytoskeletal 6C OS=Homo sapiens OX=9606 GN=KRT6C PE=1 SV=3" 8.25 2264 - 209422 - - - 0.7937 - 2.21 0.606 - 283.2 1 2 0 0.0011 17 0 0 0 5.51E+06 0.00E+00 - - - 5.4662 0.9998 221125_WJC_METTL3_EV_vs_WT_F03.10339.10339.2 6.88E-06 20-Oct R.YLAEVAC[160.03]GDDR[166.11].K "sp|P27348|1433T_HUMAN,tr|E9PG15|E9PG15_HUMAN" 2 1277.5586 1.05 27210 10339 2 1277.55794 639.7866 14-3-3 protein theta OS=Homo sapiens OX=9606 GN=YWHAQ PE=1 SV=1 4.03 2264.2 - 181710 - - - -0.4939 - 2.011 0.456 - 276.6 1 2 0 -0.0006 11 0 0 0 4.15E+07 3.95E+07 - - - 4.2988 0.7839 221125_WJC_METTL3_EV_vs_WT_F03.10342.10342.2 0.0941 14-Jun Y.VGAFADAR[166.11].S sp|Q9ULL4|PLXB3_HUMAN 1 815.4165 0.9 27211 10342 2 815.415425 408.7155 Plexin-B3 OS=Homo sapiens OX=9606 GN=PLXNB3 PE=1 SV=2 5.81 2264.6 - 7.92E+06 - - - -1.3453 - 1.367 0.195 - 90.7 1 1 0 -0.0011 8 0 0 0 9.25E+08 1.03E+09 - - - 1.4238 0.9993 221125_WJC_METTL3_EV_vs_WT_F03.10344.10344.2 0.00377 20-Sep K.SADGVIVSGVK.D "sp|Q9UNH7|SNX6_HUMAN,tr|A0A0A0MRI2|A0A0A0MRI2_HUMAN,tr|G3V5X9|G3V5X9_HUMAN" 3 1030.5659 1.71 27213 10344 2 1030.567353 516.2902 Sorting nexin-6 OS=Homo sapiens OX=9606 GN=SNX6 PE=1 SV=1 5.55 2264.7 - 1.84E+06 - - - 1.4342 - 1.741 0.358 - 229.5 1 2 0 0.0015 11 0 0 0 4.35E+07 2.54E+07 - - - 3.1847 0.9994 221125_WJC_METTL3_EV_vs_WT_F03.10345.10345.2 0.01 16-Aug R.SSLLAVSNK[136.11].Y "sp|P35658|NU214_HUMAN,tr|A0A494BZU9|A0A494BZU9_HUMAN,tr|A0A494C1F2|A0A494C1F2_HUMAN" 3 925.5324 2.44 27214 10345 2 925.533322 463.7735 Nuclear pore complex protein Nup214 OS=Homo sapiens OX=9606 GN=NUP214 PE=1 SV=2 8.47 2264.7 - 1.61E+06 - - - 1.0005 - 1.752 0.334 - 189 1 2 0 0.0009 9 0 0 0 1.05E+08 4.30E+07 - - - 3.1299 0.9912 221125_WJC_METTL3_EV_vs_WT_F03.10346.10346.2 2.56E-05 16-Sep M.VSTMSDGWK.F "sp|Q9NXV2|KCTD5_HUMAN,sp|Q14681|KCTD2_HUMAN,tr|J3QSC8|J3QSC8_HUMAN" 3 1009.4539 6.64 27215 10346 2 1009.454631 505.7342 BTB\POZ domain-containing protein KCTD5 OS=Homo sapiens OX=9606 GN=KCTD5 PE=1 SV=1 5.81 2264.8 - 1.15E+06 - - - 0.743 - 2.079 0.494 - 261.5 1 1 0 0.0008 9 0 0 0 3.53E+07 5.32E+06 - - - 4.8068 0.9996 221125_WJC_METTL3_EV_vs_WT_F03.10347.10347.2 0.000234 20-Nov K.SADGVIVSGVK[136.11].D "sp|Q9UNH7|SNX6_HUMAN,tr|A0A0A0MRI2|A0A0A0MRI2_HUMAN,tr|G3V5X9|G3V5X9_HUMAN" 3 1038.5801 1.94 27216 10347 2 1038.58133 520.2973 Sorting nexin-6 OS=Homo sapiens OX=9606 GN=SNX6 PE=1 SV=1 5.55 2264.9 - 1.01E+06 - - - 1.2084 - 1.968 0.39 - 300 1 2 0 0.0013 11 0 0 0 4.96E+07 2.55E+07 - - - 3.7526 0.9819 221125_WJC_METTL3_EV_vs_WT_F03.10348.10348.2 0.217 16-May R.LVPSVNGVR[166.11].R "sp|P11586|C1TC_HUMAN,tr|F5H2F4|F5H2F4_HUMAN,tr|V9GZ78|V9GZ78_HUMAN,tr|V9GYY3|V9GYY3_HUMAN,tr|A0A494C1T2|A0A494C1T2_HUMAN" 5 949.5584 2.21 27217 10348 2 949.559101 475.7865 "C-1-tetrahydrofolate synthase, cytoplasmic OS=Homo sapiens OX=9606 GN=MTHFD1 PE=1 SV=4" 9.75 2264.9 - 822660 - - - 0.7014 - 1.092 0.139 - 81.8 1 2 0 0.0007 9 0 0 0 3.47E+07 1.57E+07 - - - 0.3221 0.9997 221125_WJC_METTL3_EV_vs_WT_F03.10352.10352.2 0.0127 16-Oct K.EVVIVSATR[166.11].T "sp|P24752|THIL_HUMAN,tr|A0A5F9ZHL7|A0A5F9ZHL7_HUMAN,tr|A0A5F9ZHJ7|A0A5F9ZHJ7_HUMAN,tr|A0A5F9ZHH9|A0A5F9ZHH9_HUMAN,tr|A0A5F9ZHL1|A0A5F9ZHL1_HUMAN,tr|E9PRQ6|E9PRQ6_HUMAN" 6 982.5687 1.15 27219 10352 2 982.569253 492.2916 "Acetyl-CoA acetyltransferase, mitochondrial OS=Homo sapiens OX=9606 GN=ACAT1 PE=1 SV=1" 6.1 2265.5 - 3.42E+06 - - - 0.5984 - 1.873 0.373 - 525.2 1 2 0 0.0006 9 0 0 0 3.28E+08 2.85E+08 - - - 3.6113 0.9997 221125_WJC_METTL3_EV_vs_WT_F03.10353.10353.2 0.149 16-Aug K.EVVIVSATR.T "sp|P24752|THIL_HUMAN,tr|A0A5F9ZHL7|A0A5F9ZHL7_HUMAN,tr|A0A5F9ZHJ7|A0A5F9ZHJ7_HUMAN,tr|A0A5F9ZHH9|A0A5F9ZHH9_HUMAN,tr|A0A5F9ZHL1|A0A5F9ZHL1_HUMAN,tr|E9PRQ6|E9PRQ6_HUMAN" 6 972.5604 1.14 27220 10353 2 972.560874 487.2875 "Acetyl-CoA acetyltransferase, mitochondrial OS=Homo sapiens OX=9606 GN=ACAT1 PE=1 SV=1" 6.1 2265.5 - 3.62E+06 - - - 0.4925 - 1.791 0.392 - 357 1 2 0 0.0005 9 0 0 0 3.28E+08 2.87E+08 - - - 3.6222 0.9896 221125_WJC_METTL3_EV_vs_WT_F03.10354.10354.2 0.0985 12-Jun R.DYSPYYK.T "sp|P13646|K1C13_HUMAN,tr|K7EMD9|K7EMD9_HUMAN,tr|K7ERE3|K7ERE3_HUMAN" 3 934.4072 0.08 27221 10354 2 934.408443 468.2109 "Keratin, type I cytoskeletal 13 OS=Homo sapiens OX=9606 GN=KRT13 PE=1 SV=4" 5.83 2265.6 - 1.49E+06 - - - 1.2778 - 1.024 0.239 - 111.5 1 2 0 0.0012 7 0 0 0 8.26E+07 1.09E+09 - - - 0.881 1 221125_WJC_METTL3_EV_vs_WT_F03.10356.10356.2 7.27E-07 20-Dec R.YLAEVAC[160.03]GDDR.K "sp|P27348|1433T_HUMAN,tr|E9PG15|E9PG15_HUMAN" 2 1267.5503 1.05 27223 10356 2 1267.548752 634.7824 14-3-3 protein theta OS=Homo sapiens OX=9606 GN=YWHAQ PE=1 SV=1 4.03 2265.8 - 506170 - - - -1.222 - 2.419 0.632 - 547.6 1 2 0 -0.0015 11 0 0 0 4.15E+07 3.95E+07 - - - 6.0981 0.9995 221125_WJC_METTL3_EV_vs_WT_F03.10359.10359.2 0.00821 16-Sep R.QLDSIVGER.G "sp|P48668|K2C6C_HUMAN,sp|P13647|K2C5_HUMAN,sp|P02538|K2C6A_HUMAN,tr|F8W0C6|F8W0C6_HUMAN" 4 1015.5298 9.48 27224 10359 2 1015.531518 508.7722 "Keratin, type II cytoskeletal 6C OS=Homo sapiens OX=9606 GN=KRT6C PE=1 SV=3" 4.37 2266.2 - 1.44E+06 - - - 1.6681 - 1.874 0.395 - 413.5 1 2 0 0.0017 9 0 0 0 3.46E+07 3.65E+06 - - - 3.775 0.9996 221125_WJC_METTL3_EV_vs_WT_F03.10360.10360.2 0.0993 20-Sep K.VLTQMGSPSVR.C sp|Q15796|SMAD2_HUMAN 1 1173.6176 0.23 27225 10360 2 1173.618987 587.8161 Mothers against decapentaplegic homolog 2 OS=Homo sapiens OX=9606 GN=SMAD2 PE=1 SV=1 9.72 2266.3 - 511801 - - - 1.1878 - 1.93 0.375 - 361.1 1 2 0 0.0014 11 0 0 0 1.17E+07 5.17E+07 - - - 3.5891 0.9996 221125_WJC_METTL3_EV_vs_WT_F03.10361.10361.2 0.00304 16-Aug K.ATVSAPFGK.F "sp|Q15149|PLEC_HUMAN,tr|H0YDN1|H0YDN1_HUMAN" 2 876.4705 0.66 27226 10361 2 876.471578 439.2425 Plectin OS=Homo sapiens OX=9606 GN=PLEC PE=1 SV=3 8.8 2266.4 - 2.35E+06 - - - 1.2094 - 1.952 0.38 - 269.2 1 2 0 0.0011 9 0 0 0 4.72E+07 7.18E+07 - - - 3.7824 0.9857 221125_WJC_METTL3_EV_vs_WT_F03.10364.10364.2 1.91 12-Jul K.LQVQLEK.R "sp|Q9ULV0|MYO5B_HUMAN,tr|A0A0A0MR36|A0A0A0MR36_HUMAN" 2 856.5018 5.8 27229 10364 2 856.502622 429.2582 Unconventional myosin-Vb OS=Homo sapiens OX=9606 GN=MYO5B PE=1 SV=3 6 2266.6 - 520461 - - - 0.9387 - 1.265 0.103 - 132 1 2 0 0.0008 7 0 0 0 9.70E+06 1.67E+06 - - - 0.5463 0.9997 221125_WJC_METTL3_EV_vs_WT_F03.10371.10371.2 0.000177 20-Nov R.ALVDGPC[160.03]TQVR.R "sp|P50914|RL14_HUMAN,tr|E7EPB3|E7EPB3_HUMAN" 2 1214.6078 2.26 27233 10371 2 1214.60991 608.3112 60S ribosomal protein L14 OS=Homo sapiens OX=9606 GN=RPL14 PE=1 SV=4 5.87 2267.4 - 742191 - - - 1.7726 - 2.042 0.502 - 487.7 1 2 0 0.0022 11 0 0 0 3.96E+08 1.75E+08 - - - 4.6794 0.9848 221125_WJC_METTL3_EV_vs_WT_F03.10372.10372.2 0.225 18-Jul K.VLGGSFADQK.L "sp|O00507|USP9Y_HUMAN,sp|Q93008|USP9X_HUMAN" 2 1020.524 4.61 27234 10372 2 1020.525641 511.2693 Probable ubiquitin carboxyl-terminal hydrolase FAF-Y OS=Homo sapiens OX=9606 GN=USP9Y PE=2 SV=2 5.81 2267.5 - 245653 - - - 1.5982 - 1.208 0.158 - 81.6 1 2 0 0.0016 10 0 0 0 1.21E+08 2.63E+07 - - - 0.7349 0.9985 221125_WJC_METTL3_EV_vs_WT_F03.10375.10375.2 2.31E-05 18-Nov R.C[160.03]MTNTPVVVR[166.11].E "sp|P32322|P5CR1_HUMAN,tr|J3QKT4|J3QKT4_HUMAN,tr|J3QLK9|J3QLK9_HUMAN,tr|J3QL24|J3QL24_HUMAN,tr|E2QRB3|E2QRB3_HUMAN,tr|J3QL23|J3QL23_HUMAN,tr|J3QR88|J3QR88_HUMAN,tr|J3KSA9|J3KSA9_HUMAN,tr|J3KQ22|J3KQ22_HUMAN,tr|J3QL32|J3QL32_HUMAN" 10 1185.5874 1.09 27237 10375 2 1185.582414 593.801 "Pyrroline-5-carboxylate reductase 1, mitochondrial OS=Homo sapiens OX=9606 GN=PYCR1 PE=1 SV=2" 8.25 2267.8 - 558243 - - - -4.1794 - 1.969 0.5 - 481.4 1 2 0 -0.005 10 0 0 0 8.07E+06 7.41E+06 - - - 4.6236 0.7999 221125_WJC_METTL3_EV_vs_WT_F03.10380.10380.2 3.01 12-May K.FDPNEIK.V sp|P30050|RL12_HUMAN 1 861.4232 1.28 27241 10380 2 861.42433 431.7189 60S ribosomal protein L12 OS=Homo sapiens OX=9606 GN=RPL12 PE=1 SV=1 4.37 2268.4 - 1.07E+06 - - - 1.2735 - 0.938 0.003 - 66 1 2 0 0.0011 7 0 0 0 1.47E+08 1.14E+08 - - - -1.14 0.9963 221125_WJC_METTL3_EV_vs_WT_F03.10382.10382.2 0.383 12-Jul R.EAFEAIK[136.11].A "sp|Q9BQC6|RT63_HUMAN,sp|Q9H5P4|PDZD7_HUMAN,sp|P23409|MYF6_HUMAN,sp|P15173|MYOG_HUMAN" 4 814.4316 0.21 27243 10382 2 814.432921 408.2231 "Ribosomal protein 63, mitochondrial OS=Homo sapiens OX=9606 GN=MRPL57 PE=1 SV=1" 4.53 2268.5 - 819528 - - - 1.5974 - 1.707 0.141 - 195.3 1 2 0 0.0013 7 0 0 0 3.65E+06 1.78E+07 - - - 1.7764 0.9993 221125_WJC_METTL3_EV_vs_WT_F03.10384.10384.2 0.000142 16-Aug R.GFVQVDDGR.K sp|P54136|SYRC_HUMAN 1 991.4723 4.64 27245 10384 2 991.469639 496.7434 "Arginine--tRNA ligase, cytoplasmic OS=Homo sapiens OX=9606 GN=RARS1 PE=1 SV=2" 4.21 2268.7 - 500572 - - - -2.693 - 1.825 0.44 - 211.1 1 2 0 -0.0027 9 0 0 0 5.41E+07 1.17E+07 - - - 4.0304 0.873 221125_WJC_METTL3_EV_vs_WT_F03.10388.10388.2 2.82 12-Aug M.R[166.11]LSELLR[166.11].K "sp|Q92538|GBF1_HUMAN,sp|P08238|HS90B_HUMAN,tr|A0A7I2V2L4|A0A7I2V2L4_HUMAN,tr|A0A7I2YQM2|A0A7I2YQM2_HUMAN,tr|A0A7I2V3Y5|A0A7I2V3Y5_HUMAN,tr|A0A669KBG8|A0A669KBG8_HUMAN,tr|A0A7I2V2L5|A0A7I2V2L5_HUMAN,tr|A0A7I2V514|A0A7I2V514_HUMAN,tr|A0A7I2YQ65|A0A7I2YQ65_HUMAN,tr|A0A7I2V3Q4|A0A7I2V3Q4_HUMAN,tr|A0A669KB10|A0A669KB10_HUMAN,tr|A0A7I2V452|A0A7I2V452_HUMAN,tr|A0A7I2V4K2|A0A7I2V4K2_HUMAN,tr|A0A7I2V529|A0A7I2V529_HUMAN,tr|A0A7P0RGV0|A0A7P0RGV0_HUMAN" 15 905.5561 0.85 27247 10388 2 905.556758 453.7853 Golgi-specific brefeldin A-resistance guanine nucleotide exchange factor 1 OS=Homo sapiens OX=9606 GN=GBF1 PE=1 SV=2 9.6 2269.1 - 2.08E+06 - - - 0.6825 - 1.631 0.158 - 203.8 1 1 0 0.0006 7 0 0 0 4.46E+07 5.24E+07 - - - 1.7578 0.9968 221125_WJC_METTL3_EV_vs_WT_F03.10390.10390.2 0.248 14-Jul R.GPGVPFQR.G sp|P47929|LEG7_HUMAN 1 856.4555 29.06 27249 10390 2 856.456985 429.235 Galectin-7 OS=Homo sapiens OX=9606 GN=LGALS7 PE=1 SV=2 9.75 2269.3 - 971024 - - - 1.6919 - 1.438 0.242 - 207.6 1 2 0 0.0014 8 0 0 0 6.94E+08 2.39E+07 - - - 1.9235 0.9997 221125_WJC_METTL3_EV_vs_WT_F03.10392.10392.2 0.000416 16-Sep R.GFVQVDDGR[166.11].K sp|P54136|SYRC_HUMAN 1 1001.4806 3.39 27251 10392 2 1001.479417 501.7476 "Arginine--tRNA ligase, cytoplasmic OS=Homo sapiens OX=9606 GN=RARS1 PE=1 SV=2" 4.21 2269.5 - 592190 - - - -1.1603 - 1.915 0.416 - 327.8 1 2 0 -0.0012 9 0 0 0 3.59E+07 1.06E+07 - - - 3.9929 0.9998 221125_WJC_METTL3_EV_vs_WT_F03.10393.10393.2 0.000163 16-Oct R.VTELEDEVR[166.11].N "sp|Q9BV38|WDR18_HUMAN,tr|U3KQC1|U3KQC1_HUMAN,tr|A0A0A0MQU0|A0A0A0MQU0_HUMAN,tr|K7EIR0|K7EIR0_HUMAN" 4 1098.5432 1.26 27252 10393 2 1098.542868 550.2789 WD repeat-containing protein 18 OS=Homo sapiens OX=9606 GN=WDR18 PE=1 SV=2 4 2269.6 - 580697 - - - -0.3377 - 2.124 0.407 - 620.1 1 2 0 -0.0004 9 0 0 0 2.73E+08 2.16E+08 - - - 4.2263 0.9997 221125_WJC_METTL3_EV_vs_WT_F03.10394.10394.2 0.000435 20-Aug K.VLTQMGSPSVR[166.11].C sp|Q15796|SMAD2_HUMAN 1 1183.6259 0.22 27253 10394 2 1183.627915 592.8202 Mothers against decapentaplegic homolog 2 OS=Homo sapiens OX=9606 GN=SMAD2 PE=1 SV=1 9.72 2269.7 - 437377 - - - 1.7337 - 1.789 0.505 - 285.2 1 2 0 0.0021 11 0 0 0 1.17E+07 5.29E+07 - - - 4.3438 0.9994 221125_WJC_METTL3_EV_vs_WT_F03.10401.10401.2 0.0158 20-Nov R.ALVDGPC[160.03]TQVR[166.11].R "sp|P50914|RL14_HUMAN,tr|E7EPB3|E7EPB3_HUMAN" 2 1224.616 2.26 27258 10401 2 1224.617539 613.3153 60S ribosomal protein L14 OS=Homo sapiens OX=9606 GN=RPL14 PE=1 SV=4 5.87 2270.6 - 2.71E+06 - - - 1.2347 - 1.834 0.351 - 560.2 1 2 0 0.0015 11 0 0 0 3.96E+08 1.75E+08 - - - 3.2737 0.99 221125_WJC_METTL3_EV_vs_WT_F03.10403.10403.2 7.52 12-Jun K.IDIDYQK[136.11].L "sp|Q13435|SF3B2_HUMAN,tr|E9PPJ0|E9PPJ0_HUMAN" 2 901.4636 1.2 27260 10403 2 901.465239 451.7391 Splicing factor 3B subunit 2 OS=Homo sapiens OX=9606 GN=SF3B2 PE=1 SV=2 4.21 2270.7 - 3.03E+06 - - - 1.7649 - 1.342 0.153 - 86.6 1 2 0 0.0016 7 0 0 0 1.94E+08 1.62E+08 - - - 1.1026 0.9969 221125_WJC_METTL3_EV_vs_WT_F03.10404.10404.2 0.00123 16-Sep K.MFEDPETTR.Q "sp|P60228|EIF3E_HUMAN,tr|A0A7I2V3I2|A0A7I2V3I2_HUMAN,tr|A0A7I2V570|A0A7I2V570_HUMAN,tr|A0A7I2V2Q9|A0A7I2V2Q9_HUMAN,tr|H0YBP5|H0YBP5_HUMAN,tr|A0A7I2V5Z6|A0A7I2V5Z6_HUMAN,tr|A0A7I2V2H9|A0A7I2V2H9_HUMAN,tr|B3KW56|B3KW56_HUMAN,tr|A0A7I2V4B4|A0A7I2V4B4_HUMAN,tr|E5RGA2|E5RGA2_HUMAN,tr|A0A7I2V3I0|A0A7I2V3I0_HUMAN,tr|A0A7I2V3S3|A0A7I2V3S3_HUMAN,tr|A0A7I2V4G3|A0A7I2V4G3_HUMAN,tr|A0A7I2V5K7|A0A7I2V5K7_HUMAN,tr|A0A7I2V3W9|A0A7I2V3W9_HUMAN,tr|H0YBR5|H0YBR5_HUMAN,tr|A0A7I2V429|A0A7I2V429_HUMAN,tr|A0A7I2V2W0|A0A7I2V2W0_HUMAN,tr|A0A161SXE1|A0A161SXE1_HUMAN" 19 1124.4808 1.14 27261 10404 2 1124.483166 563.2477 Eukaryotic translation initiation factor 3 subunit E OS=Homo sapiens OX=9606 GN=EIF3E PE=1 SV=1 4.14 2270.7 - 1.96E+06 - - - 2.0818 - 1.466 0.274 - 268.5 1 2 0 0.0023 9 0 0 0 7.30E+07 6.41E+07 - - - 2.1707 0.9852 221125_WJC_METTL3_EV_vs_WT_F03.10405.10405.2 0.154 12-Jun K.FDPNEIK[136.11].V sp|P30050|RL12_HUMAN 1 869.4374 1.39 27262 10405 2 869.43827 435.726 60S ribosomal protein L12 OS=Homo sapiens OX=9606 GN=RPL12 PE=1 SV=1 4.37 2270.8 - 1.31E+06 - - - 0.9627 - 1.163 0.137 - 102.4 1 2 0 0.0008 7 0 0 0 6.81E+07 4.90E+07 - - - 0.5311 0.9985 221125_WJC_METTL3_EV_vs_WT_F03.10416.10416.2 0.0141 12-Aug K.YTDLVPK.E "sp|Q13573|SNW1_HUMAN,tr|G3V3A4|G3V3A4_HUMAN,tr|G3V5R3|G3V5R3_HUMAN" 3 834.4487 0.65 27271 10416 2 834.449562 418.2316 SNW domain-containing protein 1 OS=Homo sapiens OX=9606 GN=SNW1 PE=1 SV=1 5.83 2272.1 - 1.20E+06 - - - 1.009 - 1.254 0.34 - 213.7 1 2 0 0.0008 7 0 0 0 6.65E+08 1.03E+09 - - - 2.2691 0.9978 221125_WJC_METTL3_EV_vs_WT_F03.10418.10418.2 0.202 12-Jul R.YTIYSPK[136.11].D "sp|Q9P2J5|SYLC_HUMAN,tr|A0A6I8PIV1|A0A6I8PIV1_HUMAN,tr|A0A6I8PRS0|A0A6I8PRS0_HUMAN,tr|A0A6I8PLB8|A0A6I8PLB8_HUMAN,tr|A0A6I8PIP7|A0A6I8PIP7_HUMAN,tr|A0A6I8PIT3|A0A6I8PIT3_HUMAN,tr|A0A6I8PTV8|A0A6I8PTV8_HUMAN,tr|A0A6I8PRU9|A0A6I8PRU9_HUMAN,tr|A0A6I8PLB3|A0A6I8PLB3_HUMAN,tr|A0A6I8PS05|A0A6I8PS05_HUMAN,tr|B4DER1|B4DER1_HUMAN,tr|A0A6I8PL42|A0A6I8PL42_HUMAN" 12 878.4629 1.69 27273 10418 2 878.463767 440.2387 "Leucine--tRNA ligase, cytoplasmic OS=Homo sapiens OX=9606 GN=LARS1 PE=1 SV=2" 8.5 2272.2 - 933858 - - - 0.9642 - 1.416 0.242 - 176.3 1 2 0 0.0008 7 0 0 0 3.76E+07 2.23E+07 - - - 1.9303 0.9995 221125_WJC_METTL3_EV_vs_WT_F03.10419.10419.2 0.0225 18-Jul K.VLGGSFADQK[136.11].L "sp|O00507|USP9Y_HUMAN,sp|Q93008|USP9X_HUMAN" 2 1028.5382 3.69 27274 10419 2 1028.539019 515.2764 Probable ubiquitin carboxyl-terminal hydrolase FAF-Y OS=Homo sapiens OX=9606 GN=USP9Y PE=2 SV=2 5.81 2272.3 - 882764 - - - 0.7866 - 1.671 0.383 - 116.9 1 2 0 0.0008 10 0 0 0 5.00E+07 1.36E+07 - - - 3.3027 0.9998 221125_WJC_METTL3_EV_vs_WT_F03.10426.10426.2 0.0452 16-Oct K.MFEDPETTR[166.11].Q "sp|P60228|EIF3E_HUMAN,tr|A0A7I2V3I2|A0A7I2V3I2_HUMAN,tr|A0A7I2V570|A0A7I2V570_HUMAN,tr|A0A7I2V2Q9|A0A7I2V2Q9_HUMAN,tr|H0YBP5|H0YBP5_HUMAN,tr|A0A7I2V5Z6|A0A7I2V5Z6_HUMAN,tr|A0A7I2V2H9|A0A7I2V2H9_HUMAN,tr|B3KW56|B3KW56_HUMAN,tr|A0A7I2V4B4|A0A7I2V4B4_HUMAN,tr|E5RGA2|E5RGA2_HUMAN,tr|A0A7I2V3I0|A0A7I2V3I0_HUMAN,tr|A0A7I2V3S3|A0A7I2V3S3_HUMAN,tr|A0A7I2V4G3|A0A7I2V4G3_HUMAN,tr|A0A7I2V5K7|A0A7I2V5K7_HUMAN,tr|A0A7I2V3W9|A0A7I2V3W9_HUMAN,tr|H0YBR5|H0YBR5_HUMAN,tr|A0A7I2V429|A0A7I2V429_HUMAN,tr|A0A7I2V2W0|A0A7I2V2W0_HUMAN,tr|A0A161SXE1|A0A161SXE1_HUMAN" 19 1134.4891 1.14 27279 10426 2 1134.48984 568.2518 Eukaryotic translation initiation factor 3 subunit E OS=Homo sapiens OX=9606 GN=EIF3E PE=1 SV=1 4.14 2273 - 2.36E+06 - - - 0.6567 - 1.929 0.502 - 345.4 1 2 0 0.0007 9 0 0 0 7.30E+07 6.41E+07 - - - 4.6493 1 221125_WJC_METTL3_EV_vs_WT_F03.10427.10427.2 4.72E-07 16-Sep R.YDDMAAAMK.A "sp|P31946|1433B_HUMAN,sp|P61981|1433G_HUMAN,tr|Q4VY19|Q4VY19_HUMAN,tr|Q4VY20|Q4VY20_HUMAN,tr|A0A0J9YWE8|A0A0J9YWE8_HUMAN" 5 1014.4151 1.06 27280 10427 2 1014.416172 508.2148 14-3-3 protein beta\alpha OS=Homo sapiens OX=9606 GN=YWHAB PE=1 SV=3 4.21 2273.1 - 1.37E+06 - - - 1.1031 - 2.033 0.694 - 189 1 2 0 0.0011 9 0 0 0 2.50E+07 2.37E+07 - - - 6.2192 0.9992 221125_WJC_METTL3_EV_vs_WT_F03.10428.10428.2 6.44E-06 16-Sep R.YDDMAAAMK[136.11].A "sp|P31946|1433B_HUMAN,sp|P61981|1433G_HUMAN,tr|Q4VY19|Q4VY19_HUMAN,tr|Q4VY20|Q4VY20_HUMAN,tr|A0A0J9YWE8|A0A0J9YWE8_HUMAN" 5 1022.4293 1.06 27281 10428 2 1022.430063 512.2219 14-3-3 protein beta\alpha OS=Homo sapiens OX=9606 GN=YWHAB PE=1 SV=3 4.21 2273.2 - 1.12E+06 - - - 0.7922 - 1.906 0.242 - 165.4 1 2 0 0.0008 9 0 0 0 2.50E+07 2.37E+07 - - - 2.6942 0.9998 221125_WJC_METTL3_EV_vs_WT_F03.10434.10434.2 0.000155 16-Aug K.DGVVEITGK.H "sp|P04792|HSPB1_HUMAN,tr|A0A6Q8PHJ6|A0A6Q8PHJ6_HUMAN,tr|A0A6Q8PFK8|A0A6Q8PFK8_HUMAN" 3 916.4866 0.88 27285 10434 2 916.486888 459.2506 Heat shock protein beta-1 OS=Homo sapiens OX=9606 GN=HSPB1 PE=1 SV=2 4.37 2274 - 9.52E+06 - - - 0.3557 - 1.793 0.434 - 221.6 1 2 0 0.0003 9 0 0 0 6.78E+08 7.73E+08 - - - 3.9356 0.9993 221125_WJC_METTL3_EV_vs_WT_F03.10435.10435.2 0.0193 16-Sep K.SLSVATVTR[166.11].S "sp|O00443|P3C2A_HUMAN,tr|A0A0C4DGF9|A0A0C4DGF9_HUMAN" 2 942.5374 1.33 27286 10435 2 942.537451 472.276 Phosphatidylinositol 4-phosphate 3-kinase C2 domain-containing subunit alpha OS=Homo sapiens OX=9606 GN=PIK3C2A PE=1 SV=2 9.47 2274 - 1.87E+06 - - - 0.0912 - 1.551 0.323 - 272.8 1 2 0 0.0001 9 0 0 0 9.34E+07 7.03E+07 - - - 2.6964 0.9998 221125_WJC_METTL3_EV_vs_WT_F03.10440.10440.2 0.000633 22-Sep K.VLLDDTQSEAAR.V sp|Q14789|GOGB1_HUMAN 1 1316.6572 1.45 27291 10440 2 1316.655981 659.3359 Golgin subfamily B member 1 OS=Homo sapiens OX=9606 GN=GOLGB1 PE=1 SV=2 4.03 2274.6 - 198332 - - - -0.9327 - 1.742 0.537 - 207.3 1 2 0 -0.0012 12 0 0 0 1.16E+07 8.00E+06 - - - 4.4673 0.9989 221125_WJC_METTL3_EV_vs_WT_F03.10444.10444.2 0.249 14-Sep R.IYEYVESR.M "sp|Q8WWY3|PRP31_HUMAN,tr|E7EVX8|E7EVX8_HUMAN,tr|E7EU94|E7EU94_HUMAN,tr|E7ESX0|E7ESX0_HUMAN,tr|E7EN72|E7EN72_HUMAN" 5 1057.508 0.33 27293 10444 2 1057.509234 529.7613 U4\U6 small nuclear ribonucleoprotein Prp31 OS=Homo sapiens OX=9606 GN=PRPF31 PE=1 SV=2 4.53 2275.1 - 5.64E+06 - - - 1.1423 - 1.74 0.259 - 385.2 1 2 0 0.0012 8 0 0 0 5.56E+08 1.70E+09 - - - 2.6241 0.9995 221125_WJC_METTL3_EV_vs_WT_F03.10446.10446.2 0.00406 16-Sep K.SLSVATVTR.S "sp|O00443|P3C2A_HUMAN,tr|A0A0C4DGF9|A0A0C4DGF9_HUMAN" 2 932.5291 0.73 27295 10446 2 932.529112 467.2718 Phosphatidylinositol 4-phosphate 3-kinase C2 domain-containing subunit alpha OS=Homo sapiens OX=9606 GN=PIK3C2A PE=1 SV=2 9.47 2275.2 - 4.02E+06 - - - 0.0182 - 1.489 0.373 - 239.4 1 2 0 0 9 0 0 0 9.96E+07 1.37E+08 - - - 2.9477 0.9996 221125_WJC_METTL3_EV_vs_WT_F03.10447.10447.2 0.00661 18-Sep K.SVLGGQDQLR.V "sp|Q9BV38|WDR18_HUMAN,tr|U3KQC1|U3KQC1_HUMAN,tr|A0A0A0MQU0|A0A0A0MQU0_HUMAN,tr|K7EIR0|K7EIR0_HUMAN" 4 1071.5673 1.19 27296 10447 2 1071.568689 536.7909 WD repeat-containing protein 18 OS=Homo sapiens OX=9606 GN=WDR18 PE=1 SV=2 5.55 2275.2 - 3.76E+06 - - - 1.3224 - 1.621 0.454 - 274.2 1 2 0 0.0014 10 0 0 0 3.94E+08 3.30E+08 - - - 3.7421 0.9989 221125_WJC_METTL3_EV_vs_WT_F03.10449.10449.2 0.0102 20-Dec K.ALAAAGYDVEK[136.11].N "sp|P10412|H14_HUMAN,sp|Q02539|H11_HUMAN,sp|P22492|H1T_HUMAN,sp|P16403|H12_HUMAN,sp|P16402|H13_HUMAN" 5 1114.575 0.79 27298 10449 2 1114.578405 558.2948 Histone H1.4 OS=Homo sapiens OX=9606 GN=H1-4 PE=1 SV=2 4.37 2275.4 - 1.04E+06 - - - 3.0648 - 2.55 0.311 - 509.5 1 2 0 0.0034 11 0 0 0 1.75E+09 2.22E+09 - - - 3.8693 0.995 221125_WJC_METTL3_EV_vs_WT_F03.10452.10452.2 4.65 12-Jul K.IDIDYQK.L "sp|Q13435|SF3B2_HUMAN,tr|E9PPJ0|E9PPJ0_HUMAN" 2 893.4494 1.15 27300 10452 2 893.450329 447.732 Splicing factor 3B subunit 2 OS=Homo sapiens OX=9606 GN=SF3B2 PE=1 SV=2 4.21 2275.7 - 1.19E+07 - - - 0.9861 - 1.473 0.14 - 131.5 1 2 0 0.0009 7 0 0 0 1.90E+08 1.66E+08 - - - 1.3019 0.9951 221125_WJC_METTL3_EV_vs_WT_F03.10455.10455.2 0.559 18-Nov K.SLAPAPLSTK[136.11].S sp|P78337|PITX1_HUMAN 1 991.5793 3.24 27302 10455 2 991.576767 496.7969 Pituitary homeobox 1 OS=Homo sapiens OX=9606 GN=PITX1 PE=1 SV=2 8.47 2276 - 1.71E+06 - - - -2.6019 - 1.981 0.148 - 298.9 1 2 0 -0.0026 10 0 0 0 2.59E+08 7.99E+07 - - - 2.0415 0.9997 221125_WJC_METTL3_EV_vs_WT_F03.10459.10459.2 0.00542 20-Dec K.ALAAAGYDVEK.N "sp|P10412|H14_HUMAN,sp|Q02539|H11_HUMAN,sp|P22492|H1T_HUMAN,sp|P16403|H12_HUMAN,sp|P16402|H13_HUMAN" 5 1106.5608 0.78 27306 10459 2 1106.561687 554.2877 Histone H1.4 OS=Homo sapiens OX=9606 GN=H1-4 PE=1 SV=2 4.37 2276.2 - 1.47E+06 - - - 0.8115 - 2.33 0.33 - 512 1 2 0 0.0009 11 0 0 0 1.75E+09 2.23E+09 - - - 3.7664 0.7694 221125_WJC_METTL3_EV_vs_WT_F03.10461.10461.2 0.0112 22-Oct R.LFVSGAC[160.03]DASAK[136.11].L "sp|P62873|GBB1_HUMAN,tr|B3KVK2|B3KVK2_HUMAN" 2 1232.5951 0.34 27308 10461 2 1232.605164 617.3048 Guanine nucleotide-binding protein G(I)\G(S)\G(T) subunit beta-1 OS=Homo sapiens OX=9606 GN=GNB1 PE=1 SV=3 5.83 2276.4 - 342562 - - - 8.1868 - 1.709 0.152 - 249.3 1 2 0 0.0101 12 0 0 0 1.88E+07 5.59E+07 - - - 1.5706 0.9998 221125_WJC_METTL3_EV_vs_WT_F03.10465.10465.2 0.00125 16-Oct R.VTELEDEVR.N "sp|Q9BV38|WDR18_HUMAN,tr|U3KQC1|U3KQC1_HUMAN,tr|A0A0A0MQU0|A0A0A0MQU0_HUMAN,tr|K7EIR0|K7EIR0_HUMAN" 4 1088.535 1.24 27311 10465 2 1088.535163 545.2748 WD repeat-containing protein 18 OS=Homo sapiens OX=9606 GN=WDR18 PE=1 SV=2 4 2276.9 - 1.34E+07 - - - 0.1782 - 2.279 0.399 - 695.8 1 2 0 0.0002 9 0 0 0 2.67E+08 2.16E+08 - - - 4.3711 0.9885 221125_WJC_METTL3_EV_vs_WT_F03.10467.10467.2 0.386 14-Jul K.FVIATSTK[136.11].L sp|Q02878|RL6_HUMAN 1 873.5051 1.15 27312 10467 2 873.505942 437.7598 60S ribosomal protein L6 OS=Homo sapiens OX=9606 GN=RPL6 PE=1 SV=3 8.75 2277.1 - 3.43E+06 - - - 0.9422 - 1.471 0.066 - 152.5 1 2 0 0.0008 8 0 0 0 1.43E+08 1.24E+08 - - - 0.6922 0.9997 221125_WJC_METTL3_EV_vs_WT_F03.10468.10468.3 0.0108 14/40 R.LALLHEGTGPR[166.11].V sp|Q9UQE7|SMC3_HUMAN 1 1172.6541 0.87 27313 10468 3 1172.654269 391.892 Structural maintenance of chromosomes protein 3 OS=Homo sapiens OX=9606 GN=SMC3 PE=1 SV=2 6.75 2277.2 - 1.63E+06 - - - 0.1219 - 2.303 0.3 - 257.2 1 2 0 0.0001 11 0 0 0 7.33E+07 8.43E+07 - - - 4.2545 0.9906 221125_WJC_METTL3_EV_vs_WT_F03.10470.10470.2 0.671 14-Jun R.AEPPFAPR.S sp|Q96T25|ZIC5_HUMAN 1 883.4552 0.16 27315 10470 2 883.455361 442.7349 Zinc finger protein ZIC 5 OS=Homo sapiens OX=9606 GN=ZIC5 PE=1 SV=2 6.05 2277.3 - 1.28E+06 - - - 0.18 - 1.23 0.136 - 111 1 2 0 0.0002 8 0 0 0 8.86E+08 5.60E+09 - - - 0.6698 0.9999 221125_WJC_METTL3_EV_vs_WT_F03.10471.10471.2 4.68E-05 16-Nov R.VTC[160.03]LESGLR[166.11].V "sp|O75439|MPPB_HUMAN,tr|F8WAZ6|F8WAZ6_HUMAN,tr|G3V0E4|G3V0E4_HUMAN,tr|F8WBE1|F8WBE1_HUMAN,tr|F8WEA6|F8WEA6_HUMAN" 5 1043.5309 0.19 27316 10471 2 1043.531597 522.7727 Mitochondrial-processing peptidase subunit beta OS=Homo sapiens OX=9606 GN=PMPCB PE=1 SV=2 5.97 2277.4 - 587980 - - - 0.6679 - 2.311 0.485 - 585.2 1 2 0 0.0007 9 0 0 0 2.95E+06 1.54E+07 - - - 5.0464 0.987 221125_WJC_METTL3_EV_vs_WT_F03.10478.10478.2 0.000401 18-Aug R.GLLQDDAHPT.L "sp|Q86U44|MTA70_HUMAN,tr|F5H6D8|F5H6D8_HUMAN,tr|H0YFV6|H0YFV6_HUMAN,tr|B4DTN4|B4DTN4_HUMAN" 4 1065.5091 - 27321 10478 2 1065.509654 533.7618 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 4.2 2278.3 - 3.71E+07 - - - 0.5312 - 1.706 0.482 - 137.8 1 1 0 0.0006 10 0 0 0 - - - - - 4.0919 0.9929 221125_WJC_METTL3_EV_vs_WT_F03.10479.10479.2 0.0685 16-Jun K.DGVVEITGK[136.11].H "sp|P04792|HSPB1_HUMAN,tr|A0A6Q8PHJ6|A0A6Q8PHJ6_HUMAN,tr|A0A6Q8PFK8|A0A6Q8PFK8_HUMAN" 3 924.5008 0.87 27322 10479 2 924.502704 463.2577 Heat shock protein beta-1 OS=Homo sapiens OX=9606 GN=HSPB1 PE=1 SV=2 4.37 2278.4 - 2.00E+07 - - - 2.1006 - 1.397 0.221 - 105.7 2 2 0 0.0019 9 0 0 0 6.78E+08 7.76E+08 - - - 1.5055 0.9984 221125_WJC_METTL3_EV_vs_WT_F03.10480.10480.2 0.0127 14-Aug R.ALGDYDYK.C "sp|O75688|PPM1B_HUMAN,tr|B8ZZF0|B8ZZF0_HUMAN,tr|A0A3B3IS24|A0A3B3IS24_HUMAN,tr|C9JIR6|C9JIR6_HUMAN" 4 943.4287 3.1 27323 10480 2 943.428888 472.7216 Protein phosphatase 1B OS=Homo sapiens OX=9606 GN=PPM1B PE=1 SV=1 4.21 2278.4 - 5.83E+06 - - - 0.1855 - 1.209 0.318 - 192.4 1 2 0 0.0002 8 0 0 0 4.13E+09 1.33E+09 - - - 1.9621 0.9994 221125_WJC_METTL3_EV_vs_WT_F03.10481.10481.2 0.0325 16-Aug K.LDPAVQQLK.N sp|Q6KB66|K2C80_HUMAN 1 1010.576 999 27324 10481 2 1010.576139 506.2953 "Keratin, type II cytoskeletal 80 OS=Homo sapiens OX=9606 GN=KRT80 PE=1 SV=2" 5.84 2278.5 - 2.69E+06 - - - 0.092 - 1.476 0.368 - 204 1 2 0 0.0001 9 0 0 0 1.05E+08 0.00E+00 - - - 2.8854 0.9897 221125_WJC_METTL3_EV_vs_WT_F03.10482.10482.2 1.25 14-Jul R.ALGDYDYK[136.11].C "sp|O75688|PPM1B_HUMAN,tr|B8ZZF0|B8ZZF0_HUMAN,tr|A0A3B3IS24|A0A3B3IS24_HUMAN,tr|C9JIR6|C9JIR6_HUMAN" 4 951.4429 3.1 27325 10482 2 951.440255 476.7287 Protein phosphatase 1B OS=Homo sapiens OX=9606 GN=PPM1B PE=1 SV=1 4.21 2278.5 - 2.23E+06 - - - -2.7937 - 1.329 0.225 - 142.7 1 2 0 -0.0027 8 0 0 0 4.13E+09 1.33E+09 - - - 1.5598 0.8086 221125_WJC_METTL3_EV_vs_WT_F03.10483.10483.2 2.56 16-Jun K.GSIDQSVLK[136.11].E "sp|Q6KC79|NIPBL_HUMAN,tr|A0A590UJS4|A0A590UJS4_HUMAN" 2 953.5273 1.33 27326 10483 2 953.529764 477.7709 Nipped-B-like protein OS=Homo sapiens OX=9606 GN=NIPBL PE=1 SV=2 5.84 2278.6 - 1.40E+06 - - - 2.5726 - 0.971 0.059 - 62.7 1 2 0 0.0025 9 0 0 0 4.02E+07 3.02E+07 - - - -0.6091 0.9921 221125_WJC_METTL3_EV_vs_WT_F03.10484.10484.2 1.16 12-Aug K.TVTIVVR[166.11].G sp|P50991|TCPD_HUMAN 1 796.5046 0.3 27327 10484 2 796.505015 399.2596 T-complex protein 1 subunit delta OS=Homo sapiens OX=9606 GN=CCT4 PE=1 SV=4 9.41 2278.7 - 1.17E+06 - - - 0.5097 - 1.501 0.07 - 235.5 1 2 0 0.0004 7 0 0 0 1.52E+07 5.10E+07 - - - 0.8447 0.9994 221125_WJC_METTL3_EV_vs_WT_F03.10487.10487.3 0.0505 13/40 R.LALLHEGTGPR.V sp|Q9UQE7|SMC3_HUMAN 1 1162.6459 0.87 27328 10487 3 1162.644697 388.5559 Structural maintenance of chromosomes protein 3 OS=Homo sapiens OX=9606 GN=SMC3 PE=1 SV=2 6.75 2279.1 - 2.26E+06 - - - -0.9969 - 2.291 0.256 - 235.5 1 2 0 -0.0012 11 0 0 0 7.33E+07 8.43E+07 - - - 3.7488 0.8926 221125_WJC_METTL3_EV_vs_WT_F03.10489.10489.2 1.09 20-Aug R.LALLHEGTGPR.V sp|Q9UQE7|SMC3_HUMAN 1 1162.6459 1.79 27329 10489 2 1162.65265 582.3302 Structural maintenance of chromosomes protein 3 OS=Homo sapiens OX=9606 GN=SMC3 PE=1 SV=2 6.75 2279.3 - 559133 - - - 5.8436 - 1.687 0.126 - 195.8 1 2 0 0.0068 11 0 0 0 1.53E+07 8.55E+06 - - - 1.3842 0.9996 221125_WJC_METTL3_EV_vs_WT_F03.10492.10492.2 3.14E-07 22-Oct K.VLLDDTQSEAAR[166.11].V sp|Q14789|GOGB1_HUMAN 1 1326.6655 1.45 27332 10492 2 1326.662364 664.34 Golgin subfamily B member 1 OS=Homo sapiens OX=9606 GN=GOLGB1 PE=1 SV=2 4.03 2279.6 - 439574 - - - -2.348 - 2.055 0.52 - 354.7 1 2 0 -0.0031 12 0 0 0 1.16E+07 8.00E+06 - - - 4.7759 0.9996 221125_WJC_METTL3_EV_vs_WT_F03.10496.10496.2 0.0286 16-Nov R.LEQEIATYR.R "sp|Q04695|K1C17_HUMAN,sp|P02533|K1C14_HUMAN,sp|P08727|K1C19_HUMAN,sp|P35900|K1C20_HUMAN,sp|P08779|K1C16_HUMAN,sp|P19012|K1C15_HUMAN,sp|Q8N1A0|KT222_HUMAN,sp|P13646|K1C13_HUMAN,tr|A0A3B3IS58|A0A3B3IS58_HUMAN,tr|F5GWP8|F5GWP8_HUMAN,tr|K7ERE3|K7ERE3_HUMAN,tr|A8MT21|A8MT21_HUMAN" 12 1121.5717 26785.32 27334 10496 2 1121.570395 561.7931 "Keratin, type I cytoskeletal 17 OS=Homo sapiens OX=9606 GN=KRT17 PE=1 SV=2" 4.53 2280.1 - 3.76E+06 - - - -1.1528 - 2.102 0.338 - 508.8 1 2 0 -0.0013 9 0 0 0 1.35E+10 5.03E+05 - - - 3.6863 0.8229 221125_WJC_METTL3_EV_vs_WT_F03.10497.10497.2 2.16 12-Aug D.LQQILQR.K "sp|Q8IWN7|RP1L1_HUMAN,sp|Q9H160|ING2_HUMAN,sp|Q96EU6|RRP36_HUMAN,tr|C9J4X5|C9J4X5_HUMAN" 4 897.5396 1.52 27335 10497 2 897.539438 449.7771 Retinitis pigmentosa 1-like 1 protein OS=Homo sapiens OX=9606 GN=RP1L1 PE=1 SV=5 9.75 2280.1 - 3.83E+06 - - - -0.1805 - 1.673 0.091 - 197.9 1 1 0 -0.0002 7 0 0 0 9.75E+07 6.40E+07 - - - 1.3437 0.9986 221125_WJC_METTL3_EV_vs_WT_F03.10502.10502.2 0.000617 18-Sep K.LVDEEPQLTK.R sp|Q9UG63|ABCF2_HUMAN 1 1170.6132 4.2 27338 10502 2 1170.609899 586.3139 ATP-binding cassette sub-family F member 2 OS=Homo sapiens OX=9606 GN=ABCF2 PE=1 SV=2 4.14 2280.7 - 780742 - - - -2.8361 - 1.61 0.41 - 205.8 1 2 0 -0.0033 10 0 0 0 6.24E+08 1.48E+08 - - - 3.3975 0.9997 221125_WJC_METTL3_EV_vs_WT_F03.10508.10508.2 0.00238 14-Jul K.STLDTFGK.L "sp|Q9BY49|PECR_HUMAN,tr|B4DJS2|B4DJS2_HUMAN" 2 867.4338 1.49 27342 10508 2 867.433503 434.7242 Peroxisomal trans-2-enoyl-CoA reductase OS=Homo sapiens OX=9606 GN=PECR PE=1 SV=2 5.55 2281.4 - 5.13E+06 - - - -0.3401 - 1.521 0.424 - 189.7 1 2 0 -0.0003 8 0 0 0 2.63E+08 1.77E+08 - - - 3.4374 0.9988 221125_WJC_METTL3_EV_vs_WT_F03.10509.10509.2 0.227 14-Jul K.STLDTFGK[136.11].L "sp|Q9BY49|PECR_HUMAN,tr|B4DJS2|B4DJS2_HUMAN" 2 875.448 1.51 27343 10509 2 875.446967 438.7313 Peroxisomal trans-2-enoyl-CoA reductase OS=Homo sapiens OX=9606 GN=PECR PE=1 SV=2 5.55 2281.5 - 4.24E+06 - - - -1.1777 - 1.414 0.321 - 195.9 1 2 0 -0.001 8 0 0 0 2.44E+08 1.62E+08 - - - 2.4564 0.9996 221125_WJC_METTL3_EV_vs_WT_F03.10512.10512.2 7.05E-05 18-Nov K.LVDEEPQLTK[136.11].R sp|Q9UG63|ABCF2_HUMAN 1 1178.6274 3.98 27344 10512 2 1178.624892 590.321 ATP-binding cassette sub-family F member 2 OS=Homo sapiens OX=9606 GN=ABCF2 PE=1 SV=2 4.14 2281.9 - 3.00E+06 - - - -2.144 - 1.828 0.47 - 331 1 2 0 -0.0025 10 0 0 0 5.91E+08 1.48E+08 - - - 4.1954 0.9994 221125_WJC_METTL3_EV_vs_WT_F03.10514.10514.2 0.00269 14-Jul R.SMMSAYER.S "sp|P18583|SON_HUMAN,sp|P18583|SON_HUMAN,sp|P18583|SON_HUMAN,sp|P18583|SON_HUMAN,tr|H7C1M2|H7C1M2_HUMAN,tr|H7C1M2|H7C1M2_HUMAN" 6 973.3997 1.28 27346 10514 2 973.398374 487.7071 Protein SON OS=Homo sapiens OX=9606 GN=SON PE=1 SV=4 5.72 2282 - 1.79E+06 - - - -1.4002 - 1.278 0.458 - 210.8 1 2 0 -0.0014 8 0 0 0 2.80E+08 2.19E+08 - - - 3.1632 0.9977 221125_WJC_METTL3_EV_vs_WT_F03.10517.10517.2 0.545 18-Oct K.LQAELQGAVR[166.11].T sp|O75150|BRE1B_HUMAN 1 1093.6119 1.93 27347 10517 2 1093.611659 547.8132 E3 ubiquitin-protein ligase BRE1B OS=Homo sapiens OX=9606 GN=RNF40 PE=1 SV=5 6 2282.4 - 1.19E+06 - - - -0.2451 - 1.752 0.143 - 186.9 1 2 0 -0.0003 10 0 0 0 1.18E+08 6.12E+07 - - - 1.6624 0.9997 221125_WJC_METTL3_EV_vs_WT_F03.10531.10531.2 0.000128 14-Jul R.SMMSAYER[166.11].S "sp|P18583|SON_HUMAN,sp|P18583|SON_HUMAN,sp|P18583|SON_HUMAN,sp|P18583|SON_HUMAN,tr|H7C1M2|H7C1M2_HUMAN,tr|H7C1M2|H7C1M2_HUMAN" 6 983.408 1.28 27353 10531 2 983.406788 492.7113 Protein SON OS=Homo sapiens OX=9606 GN=SON PE=1 SV=4 5.72 2284.2 - 5.53E+06 - - - -1.2396 - 1.505 0.515 - 221.9 1 2 0 -0.0012 8 0 0 0 2.80E+08 2.19E+08 - - - 4.0773 0.9995 221125_WJC_METTL3_EV_vs_WT_F03.10533.10533.2 0.00532 16-Aug K.ASITALEAK.L sp|P35579|MYH9_HUMAN 1 902.5073 1 27354 10533 2 902.50547 452.2609 Myosin-9 OS=Homo sapiens OX=9606 GN=MYH9 PE=1 SV=4 6.05 2284.4 - 2.19E+07 - - - -2.0244 - 1.756 0.43 - 176.2 1 2 0 -0.0018 9 0 0 0 6.05E+08 6.04E+08 - - - 3.8453 0.9972 221125_WJC_METTL3_EV_vs_WT_F03.10534.10534.2 0.0417 14-Jun K.INIMNEEK.V sp|Q8N0T1|RBIS_HUMAN 1 989.4852 1.38 27355 10534 2 989.482804 495.7499 Ribosomal biogenesis factor OS=Homo sapiens OX=9606 GN=RBIS PE=1 SV=4 4.53 2284.4 - 4.25E+06 - - - -2.4033 - 1.45 0.302 - 73.3 1 2 0 -0.0024 8 0 0 0 1.23E+08 8.92E+07 - - - 2.3914 0.9985 221125_WJC_METTL3_EV_vs_WT_F03.10536.10536.2 0.000365 13/22 R.LFVSGAC[160.03]DASAK.L "sp|P62873|GBB1_HUMAN,tr|B3KVK2|B3KVK2_HUMAN" 2 1224.5809 0.34 27357 10536 2 1224.57702 613.2977 Guanine nucleotide-binding protein G(I)\G(S)\G(T) subunit beta-1 OS=Homo sapiens OX=9606 GN=GNB1 PE=1 SV=3 5.83 2284.7 - 708950 - - - -3.1464 - 1.718 0.421 - 512.8 1 2 0 -0.0039 12 0 0 0 1.88E+07 5.58E+07 - - - 3.5732 0.9871 221125_WJC_METTL3_EV_vs_WT_F03.10539.10539.2 1.04 14-Aug K.K[136.11]IFVGGIK[136.11].E "sp|Q32P51|RA1L2_HUMAN,sp|P51991|ROA3_HUMAN,sp|Q13151|ROA0_HUMAN,sp|P09651|ROA1_HUMAN,sp|P22626|ROA2_HUMAN,tr|A0A7I2YQN4|A0A7I2YQN4_HUMAN,tr|A0A7I2YQX9|A0A7I2YQX9_HUMAN,tr|A0A7I2V4N0|A0A7I2V4N0_HUMAN,tr|A0A024RA28|A0A024RA28_HUMAN,tr|A0A7I2V4N1|A0A7I2V4N1_HUMAN,tr|A0A7I2V5D8|A0A7I2V5D8_HUMAN,tr|A0A7I2V2R3|A0A7I2V2R3_HUMAN,tr|A0A7I2V4I6|A0A7I2V4I6_HUMAN,tr|F8VZ49|F8VZ49_HUMAN,tr|A0A7I2V3R8|A0A7I2V3R8_HUMAN,tr|A0A087WUI2|A0A087WUI2_HUMAN,tr|A0A7I2V4S4|A0A7I2V4S4_HUMAN,tr|F8VTQ5|F8VTQ5_HUMAN,tr|F8W6I7|F8W6I7_HUMAN,tr|A0A7I2V2L6|A0A7I2V2L6_HUMAN,tr|A0A7I2V4J6|A0A7I2V4J6_HUMAN,tr|A0A7I2V323|A0A7I2V323_HUMAN,tr|A0A7I2V3W0|A0A7I2V3W0_HUMAN,tr|A0A7I2V4G0|A0A7I2V4G0_HUMAN,tr|A0A7I2V5U9|A0A7I2V5U9_HUMAN,tr|A0A2R8Y4L2|A0A2R8Y4L2_HUMAN,tr|A0A7I2V402|A0A7I2V402_HUMAN,tr|A0A7I2V3P1|A0A7I2V3P1_HUMAN,tr|A0A7I2V3P7|A0A7I2V3P7_HUMAN" 29 876.5768 1.32 27358 10539 2 876.574666 439.2957 Heterogeneous nuclear ribonucleoprotein A1-like 2 OS=Homo sapiens OX=9606 GN=HNRNPA1L2 PE=2 SV=2 10 2285.1 - 4.58E+06 - - - -2.4048 - 1.465 0.133 - 225.7 1 2 0 -0.0021 8 0 0 0 3.68E+08 2.78E+08 - - - 1.1743 0.9983 221125_WJC_METTL3_EV_vs_WT_F03.10541.10541.2 0.163 14-Jul K.KIFVGGIK.E "sp|Q32P51|RA1L2_HUMAN,sp|P51991|ROA3_HUMAN,sp|Q13151|ROA0_HUMAN,sp|P09651|ROA1_HUMAN,sp|P22626|ROA2_HUMAN,tr|A0A7I2YQN4|A0A7I2YQN4_HUMAN,tr|A0A7I2YQX9|A0A7I2YQX9_HUMAN,tr|A0A7I2V4N0|A0A7I2V4N0_HUMAN,tr|A0A024RA28|A0A024RA28_HUMAN,tr|A0A7I2V4N1|A0A7I2V4N1_HUMAN,tr|A0A7I2V5D8|A0A7I2V5D8_HUMAN,tr|A0A7I2V2R3|A0A7I2V2R3_HUMAN,tr|A0A7I2V4I6|A0A7I2V4I6_HUMAN,tr|F8VZ49|F8VZ49_HUMAN,tr|A0A7I2V3R8|A0A7I2V3R8_HUMAN,tr|A0A087WUI2|A0A087WUI2_HUMAN,tr|A0A7I2V4S4|A0A7I2V4S4_HUMAN,tr|F8VTQ5|F8VTQ5_HUMAN,tr|F8W6I7|F8W6I7_HUMAN,tr|A0A7I2V2L6|A0A7I2V2L6_HUMAN,tr|A0A7I2V4J6|A0A7I2V4J6_HUMAN,tr|A0A7I2V323|A0A7I2V323_HUMAN,tr|A0A7I2V3W0|A0A7I2V3W0_HUMAN,tr|A0A7I2V4G0|A0A7I2V4G0_HUMAN,tr|A0A7I2V5U9|A0A7I2V5U9_HUMAN,tr|A0A2R8Y4L2|A0A2R8Y4L2_HUMAN,tr|A0A7I2V402|A0A7I2V402_HUMAN,tr|A0A7I2V3P1|A0A7I2V3P1_HUMAN,tr|A0A7I2V3P7|A0A7I2V3P7_HUMAN" 29 860.5484 1.42 27360 10541 2 860.54886 431.2815 Heterogeneous nuclear ribonucleoprotein A1-like 2 OS=Homo sapiens OX=9606 GN=HNRNPA1L2 PE=2 SV=2 10 2285.3 - 3.07E+06 - - - 0.5648 - 1.609 0.205 - 175.8 1 2 0 0.0005 8 0 0 0 3.96E+08 2.78E+08 - - - 1.9894 0.9824 221125_WJC_METTL3_EV_vs_WT_F03.10542.10542.2 0.0794 16-Sep K.ISSVSEVMK.E "sp|Q16891|MIC60_HUMAN,tr|B9A067|B9A067_HUMAN,tr|A0A087WYS0|A0A087WYS0_HUMAN,tr|D6RAW4|D6RAW4_HUMAN,tr|C9J406|C9J406_HUMAN,tr|H7C463|H7C463_HUMAN" 6 978.5056 1.06 27361 10542 2 978.500789 490.2601 MICOS complex subunit MIC60 OS=Homo sapiens OX=9606 GN=IMMT PE=1 SV=1 6 2285.3 - 3.00E+06 - - - -4.8993 - 1.684 0.247 - 154.7 1 2 0 -0.0048 9 0 0 0 8.59E+08 8.13E+08 - - - 2.3716 0.999 221125_WJC_METTL3_EV_vs_WT_F03.10547.10547.2 0.0197 16-Oct K.LQEQVTDLR.S sp|P12270|TPR_HUMAN 1 1100.5826 1.36 27364 10547 2 1100.581869 551.2986 Nucleoprotein TPR OS=Homo sapiens OX=9606 GN=TPR PE=1 SV=3 4.37 2285.9 - 1.69E+06 - - - -0.6533 - 2.067 0.168 - 374.6 1 2 0 -0.0007 9 0 0 0 4.03E+08 2.97E+08 - - - 2.3823 0.9997 221125_WJC_METTL3_EV_vs_WT_F03.10549.10549.2 0.000191 22-Nov K.VYVGNLGTGAGK.G "sp|Q16629|SRSF7_HUMAN,tr|C9JAB2|C9JAB2_HUMAN,tr|A0A0B4J1Z1|A0A0B4J1Z1_HUMAN" 3 1134.6033 0.9 27365 10549 2 1134.601194 568.3089 Serine\arginine-rich splicing factor 7 OS=Homo sapiens OX=9606 GN=SRSF7 PE=1 SV=1 8.56 2286.2 - 2.21E+06 - - - -1.8764 - 2.119 0.464 - 340.8 1 2 0 -0.0021 12 0 0 0 7.47E+08 8.26E+08 - - - 4.4433 0.9993 221125_WJC_METTL3_EV_vs_WT_F03.10559.10559.2 0.0282 16-Aug R.AAAFEQLQK.W sp|O94826|TOM70_HUMAN 1 1004.5291 1.31 27371 10559 2 1004.528603 503.2718 Mitochondrial import receptor subunit TOM70 OS=Homo sapiens OX=9606 GN=TOMM70 PE=1 SV=1 6.05 2287.4 - 6.85E+06 - - - -0.4898 - 1.324 0.392 - 238.2 1 2 0 -0.0005 9 0 0 0 1.21E+08 9.23E+07 - - - 2.7481 0.9993 221125_WJC_METTL3_EV_vs_WT_F03.10561.10561.2 0.000948 16-Aug R.VIMITGDNK[136.11].G "sp|P16615|AT2A2_HUMAN,sp|O14983|AT2A1_HUMAN,tr|H7C5W9|H7C5W9_HUMAN" 3 997.5358 1.74 27372 10561 2 997.53442 499.7752 Sarcoplasmic\endoplasmic reticulum calcium ATPase 2 OS=Homo sapiens OX=9606 GN=ATP2A2 PE=1 SV=1 5.81 2287.6 - 1.36E+06 - - - -1.3503 - 1.698 0.341 - 143 1 2 0 -0.0013 9 0 0 0 1.40E+08 8.02E+07 - - - 3.0909 1 221125_WJC_METTL3_EV_vs_WT_F03.10563.10563.2 1.45E-07 15/24 K.FAAATGATPIAGR.F "sp|P08865|RSSA_HUMAN,tr|C9J9K3|C9J9K3_HUMAN,tr|A0A0C4DG17|A0A0C4DG17_HUMAN,tr|F8WD59|F8WD59_HUMAN" 4 1202.6408 0.71 27373 10563 2 1202.638537 602.3277 40S ribosomal protein SA OS=Homo sapiens OX=9606 GN=RPSA PE=1 SV=4 9.75 2287.8 - 2.89E+06 - - - -1.8576 - 2.723 0.579 - 757.5 1 2 0 -0.0022 13 0 0 0 8.22E+08 1.15E+09 - - - 5.8878 0.9989 221125_WJC_METTL3_EV_vs_WT_F03.10564.10564.2 0.0199 20-Oct K.LTPLSHEVISR[166.11].Q "sp|Q2VIR3|IF2GL_HUMAN,sp|P41091|IF2G_HUMAN,tr|H7BZU1|H7BZU1_HUMAN" 3 1260.7066 0.67 27374 10564 2 1260.704483 631.3606 Eukaryotic translation initiation factor 2 subunit 3B OS=Homo sapiens OX=9606 GN=EIF2S3B PE=2 SV=2 6.75 2288 - 666604 - - - -1.6443 - 1.71 0.308 - 281.1 1 2 0 -0.0021 11 0 0 0 2.20E+07 3.30E+07 - - - 2.7666 0.9997 221125_WJC_METTL3_EV_vs_WT_F03.10565.10565.2 1.18E-05 20-Nov K.IGSTIDDTISK[136.11].F sp|Q14677|EPN4_HUMAN 1 1156.6067 1.54 27375 10565 2 1156.604418 579.3106 Clathrin interactor 1 OS=Homo sapiens OX=9606 GN=CLINT1 PE=1 SV=1 4.21 2288 - 1.39E+07 - - - -1.9592 - 2.443 0.45 - 281.7 1 2 0 -0.0023 11 0 0 0 2.00E+09 1.30E+09 - - - 4.7804 0.9997 221125_WJC_METTL3_EV_vs_WT_F03.10568.10568.2 0.0123 20-Dec K.IGSTIDDTISK.F sp|Q14677|EPN4_HUMAN 1 1148.5925 1.54 27376 10568 2 1148.589699 575.3035 Clathrin interactor 1 OS=Homo sapiens OX=9606 GN=CLINT1 PE=1 SV=1 4.21 2288.4 - 2.43E+07 - - - -2.4247 - 2.719 0.445 - 371.5 1 2 0 -0.0028 11 0 0 0 2.00E+09 1.30E+09 - - - 5.0328 0.9953 221125_WJC_METTL3_EV_vs_WT_F03.10570.10570.2 0.107 18-Sep K.LLSESAQPLK.K sp|Q9H3N1|TMX1_HUMAN 1 1084.6128 1.7 27378 10570 2 1084.61026 543.3137 Thioredoxin-related transmembrane protein 1 OS=Homo sapiens OX=9606 GN=TMX1 PE=1 SV=1 6 2288.6 - 6.52E+06 - - - -2.3649 - 1.769 0.177 - 176.5 1 2 0 -0.0026 10 0 0 0 1.70E+08 1.00E+08 - - - 1.9397 0.9793 221125_WJC_METTL3_EV_vs_WT_F03.10571.10571.3 0.28 Nov-48 K.VIMVTGDHPITAK[136.11].A "sp|P05023|AT1A1_HUMAN,sp|P13637|AT1A3_HUMAN,sp|Q13733|AT1A4_HUMAN,sp|P50993|AT1A2_HUMAN,sp|P54707|AT12A_HUMAN,sp|P20648|ATP4A_HUMAN,tr|A0A0A0MT26|A0A0A0MT26_HUMAN,tr|H0Y7C1|H0Y7C1_HUMAN,tr|A0A2R8YEY8|A0A2R8YEY8_HUMAN,tr|B1AKY9|B1AKY9_HUMAN,tr|M0R116|M0R116_HUMAN" 11 1388.7577 1.42 27379 10571 3 1388.753523 463.9265 Sodium\potassium-transporting ATPase subunit alpha-1 OS=Homo sapiens OX=9606 GN=ATP1A1 PE=1 SV=1 6.71 2288.6 - 3.71E+06 - - - -3.0236 - 1.685 0.199 - 94.9 1 2 0 -0.0042 13 0 0 0 1.36E+08 9.56E+07 - - - 2.1721 0.9973 221125_WJC_METTL3_EV_vs_WT_F03.10575.10575.2 0.011 18-Oct K.EGIVQTEQIR[166.11].S "sp|Q6P1J9|CDC73_HUMAN,tr|A0A2R8Y640|A0A2R8Y640_HUMAN,tr|A0A2R8YHB3|A0A2R8YHB3_HUMAN,tr|A0A1B0GUB2|A0A1B0GUB2_HUMAN,tr|A0A3B3IRP5|A0A3B3IRP5_HUMAN" 5 1181.628 2.98 27380 10575 2 1181.622882 591.8213 Parafibromin OS=Homo sapiens OX=9606 GN=CDC73 PE=1 SV=1 4.53 2289.2 - 2.38E+06 - - - -4.3068 - 2.22 0.353 - 333.6 1 2 0 -0.0051 10 0 0 0 4.76E+08 1.60E+08 - - - 3.8727 1 221125_WJC_METTL3_EV_vs_WT_F03.10577.10577.2 6.85E-08 14/24 K.FAAATGATPIAGR[166.11].F "sp|P08865|RSSA_HUMAN,tr|C9J9K3|C9J9K3_HUMAN,tr|A0A0C4DG17|A0A0C4DG17_HUMAN,tr|F8WD59|F8WD59_HUMAN" 4 1212.649 0.71 27382 10577 2 1212.647099 607.3318 40S ribosomal protein SA OS=Homo sapiens OX=9606 GN=RPSA PE=1 SV=4 9.75 2289.3 - 1.08E+07 - - - -1.6015 - 2.845 0.618 - 744.7 1 2 0 -0.0019 13 0 0 0 8.22E+08 1.15E+09 - - - 6.2884 0.9978 221125_WJC_METTL3_EV_vs_WT_F03.10578.10578.2 0.107 16-Aug R.MEDFEDDPR[166.11].A sp|Q9H1Z4|WDR13_HUMAN 1 1162.4476 1.45 27383 10578 2 1162.445249 582.2311 WD repeat-containing protein 13 OS=Homo sapiens OX=9606 GN=WDR13 PE=1 SV=2 3.77 2289.5 - 965579 - - - -2.0431 - 1.085 0.421 - 157.4 1 2 0 -0.0024 9 0 0 0 2.42E+07 1.66E+07 - - - 2.3858 0.9997 221125_WJC_METTL3_EV_vs_WT_F03.10582.10582.2 3.69E-05 18-Oct K.AEPVEVVAPR[166.11].G "sp|P09874|PARP1_HUMAN,tr|A0A7I2V3E1|A0A7I2V3E1_HUMAN" 2 1075.5901 1.16 27384 10582 2 1075.588664 538.8023 Poly [ADP-ribose] polymerase 1 OS=Homo sapiens OX=9606 GN=PARP1 PE=1 SV=4 4.53 2290 - 5.23E+06 - - - -1.362 - 1.932 0.43 - 419.2 1 2 0 -0.0015 10 0 0 0 9.98E+08 8.62E+08 - - - 4.0547 0.9849 221125_WJC_METTL3_EV_vs_WT_F03.10583.10583.2 9.89 12-Jul R.SEVDMLK.L "sp|P07355|ANXA2_HUMAN,sp|A6NMY6|AXA2L_HUMAN,tr|H0YL33|H0YL33_HUMAN,tr|H0YMW4|H0YMW4_HUMAN" 4 820.4001 7.83 27385 10583 2 820.397915 411.2073 Annexin A2 OS=Homo sapiens OX=9606 GN=ANXA2 PE=1 SV=2 4.37 2290.1 - 1.72E+06 - - - -2.6085 - 1.407 0.142 - 278.3 1 2 0 -0.0021 7 0 0 0 7.18E+07 9.17E+06 - - - 1.1711 0.9987 221125_WJC_METTL3_EV_vs_WT_F03.10584.10584.2 3.42E-05 18-Sep K.STIQTAEALR.L "sp|Q16875|F263_HUMAN,tr|A0A1W2PR17|A0A1W2PR17_HUMAN,tr|Q5W015|Q5W015_HUMAN,tr|F2Z2I2|F2Z2I2_HUMAN,tr|H0Y483|H0Y483_HUMAN,tr|Q5VX20|Q5VX20_HUMAN" 6 1088.5826 4.48 27386 10584 2 1088.581022 545.2986 "6-phosphofructo-2-kinase\fructose-2,6-bisphosphatase 3 OS=Homo sapiens OX=9606 GN=PFKFB3 PE=1 SV=1" 5.72 2290.2 - 5.07E+06 - - - -1.4386 - 1.823 0.237 - 215.3 1 2 0 -0.0016 10 0 0 0 7.52E+08 1.68E+08 - - - 2.4671 0.9961 221125_WJC_METTL3_EV_vs_WT_F03.10585.10585.2 0.295 14-Jul K.DLEGLSQR.H sp|P35579|MYH9_HUMAN 1 916.4614 1 27387 10585 2 916.459473 459.238 Myosin-9 OS=Homo sapiens OX=9606 GN=MYH9 PE=1 SV=4 4.37 2290.2 - 4.56E+06 - - - -2.1136 - 1.457 0.239 - 166.6 1 2 0 -0.0019 8 0 0 0 5.01E+08 5.01E+08 - - - 1.9408 0.9997 221125_WJC_METTL3_EV_vs_WT_F03.10589.10589.2 7.97E-05 18-Sep K.AEPVEVVAPR.G "sp|P09874|PARP1_HUMAN,tr|A0A7I2V3E1|A0A7I2V3E1_HUMAN" 2 1065.5819 1.16 27389 10589 2 1065.580568 533.7982 Poly [ADP-ribose] polymerase 1 OS=Homo sapiens OX=9606 GN=PARP1 PE=1 SV=4 4.53 2290.7 - 7.61E+06 - - - -1.2115 - 1.709 0.471 - 347.8 1 2 0 -0.0013 10 0 0 0 1.00E+09 8.62E+08 - - - 4.0153 0.9997 221125_WJC_METTL3_EV_vs_WT_F03.10590.10590.2 0.000779 18-Oct R.GVPQQIEVAR[166.11].Q sp|Q96I24|FUBP3_HUMAN 1 1105.6119 1.79 27390 10590 2 1105.61116 553.8132 Far upstream element-binding protein 3 OS=Homo sapiens OX=9606 GN=FUBP3 PE=1 SV=2 6 2290.8 - 5.37E+06 - - - -0.6937 - 1.979 0.397 - 424.1 1 2 0 -0.0008 10 0 0 0 3.06E+09 1.71E+09 - - - 3.8783 0.9983 221125_WJC_METTL3_EV_vs_WT_F03.10593.10593.2 0.31 16-Oct K.LQEQVTDLR[166.11].S sp|P12270|TPR_HUMAN 1 1110.5909 1.12 27391 10593 2 1110.588784 556.3027 Nucleoprotein TPR OS=Homo sapiens OX=9606 GN=TPR PE=1 SV=3 4.37 2291.2 - 3.67E+06 - - - -1.8675 - 2.03 0.194 - 395.6 1 2 0 -0.0021 9 0 0 0 4.06E+08 3.63E+08 - - - 2.5216 0.9352 221125_WJC_METTL3_EV_vs_WT_F03.10594.10594.2 0.307 14-Jul R.ELAVQIQK[136.11].G sp|P38919|IF4A3_HUMAN 1 935.5531 1.45 27392 10594 2 935.550475 468.7838 Eukaryotic initiation factor 4A-III OS=Homo sapiens OX=9606 GN=EIF4A3 PE=1 SV=4 6.1 2291.2 - 2.99E+06 - - - -2.84 - 1.438 0.035 - 225.2 2 2 0 -0.0027 8 0 0 0 4.93E+08 3.40E+08 - - - 0.2598 0.9995 221125_WJC_METTL3_EV_vs_WT_F03.10595.10595.2 0.104 14-Sep K.WDQTLAAR[166.11].R sp|Q86U86|PB1_HUMAN 1 969.4907 1.53 27393 10595 2 969.489438 485.7527 Protein polybromo-1 OS=Homo sapiens OX=9606 GN=PBRM1 PE=1 SV=1 5.84 2291.3 - 5.16E+06 - - - -1.3523 - 1.709 0.379 - 385.2 1 2 0 -0.0013 8 0 0 0 2.29E+08 1.50E+08 - - - 3.4562 0.9998 221125_WJC_METTL3_EV_vs_WT_F03.10597.10597.2 0.00032 20-Oct K.ADVVDSETVVR.A "sp|Q9H6T0|ESRP2_HUMAN,tr|J3QKU3|J3QKU3_HUMAN" 2 1188.5986 1.03 27395 10597 2 1188.599282 595.3066 Epithelial splicing regulatory protein 2 OS=Homo sapiens OX=9606 GN=ESRP2 PE=1 SV=1 4.03 2291.6 - 669107 - - - 0.5469 - 1.901 0.431 - 444.7 1 2 0 0.0006 11 0 0 0 5.63E+07 5.45E+07 - - - 3.962 0.9995 221125_WJC_METTL3_EV_vs_WT_F03.10600.10600.2 0.0224 20-Sep R.GTGIVSAPVPK.K "sp|P15880|RS2_HUMAN,tr|I3L404|I3L404_HUMAN,tr|E9PM36|E9PM36_HUMAN,tr|E9PQD7|E9PQD7_HUMAN,tr|E9PMM9|E9PMM9_HUMAN,tr|H0YEN5|H0YEN5_HUMAN" 6 1024.5917 1.1 27396 10600 2 1024.590696 513.3031 40S ribosomal protein S2 OS=Homo sapiens OX=9606 GN=RPS2 PE=1 SV=2 8.75 2291.9 - 1.39E+07 - - - -0.976 - 1.786 0.354 - 266.4 1 2 0 -0.001 11 0 0 0 1.38E+09 1.25E+09 - - - 3.2243 0.9989 221125_WJC_METTL3_EV_vs_WT_F03.10601.10601.2 0.00264 12-Jul K.AANWYER.E sp|O75489|NDUS3_HUMAN 1 908.4141 1.09 27397 10601 2 908.411488 455.2143 "NADH dehydrogenase [ubiquinone] iron-sulfur protein 3, mitochondrial OS=Homo sapiens OX=9606 GN=NDUFS3 PE=1 SV=1" 6.05 2292 - 1.67E+06 - - - -2.8379 - 1.49 0.456 - 201.9 1 2 0 -0.0026 7 0 0 0 6.26E+07 5.75E+07 - - - 3.6718 0.9998 221125_WJC_METTL3_EV_vs_WT_F03.10606.10606.2 0.00015 18-Oct K.QLTQEMMTEK.E sp|Q86UP2|KTN1_HUMAN 1 1237.5683 1.38 27400 10606 2 1237.568746 619.7914 Kinectin OS=Homo sapiens OX=9606 GN=KTN1 PE=1 SV=1 4.53 2292.6 - 619685 - - - 0.3935 - 1.799 0.468 - 336.6 1 2 0 0.0005 10 0 0 0 2.44E+07 1.77E+07 - - - 4.1366 0.9996 221125_WJC_METTL3_EV_vs_WT_F03.10613.10613.2 0.00121 20-Sep K.QLQAETEPIVK[136.11].M "sp|P60228|EIF3E_HUMAN,tr|A0A7I2V3I2|A0A7I2V3I2_HUMAN,tr|A0A7I2V570|A0A7I2V570_HUMAN,tr|A0A7I2V2Q9|A0A7I2V2Q9_HUMAN,tr|H0YBP5|H0YBP5_HUMAN,tr|A0A7I2V5Z6|A0A7I2V5Z6_HUMAN,tr|A0A7I2V2H9|A0A7I2V2H9_HUMAN,tr|B3KW56|B3KW56_HUMAN,tr|A0A7I2V4B4|A0A7I2V4B4_HUMAN,tr|A0A7I2V3I0|A0A7I2V3I0_HUMAN,tr|A0A7I2V3S3|A0A7I2V3S3_HUMAN,tr|A0A7I2V4G3|A0A7I2V4G3_HUMAN,tr|A0A7I2V3W9|A0A7I2V3W9_HUMAN,tr|H0YBR5|H0YBR5_HUMAN,tr|A0A7I2V429|A0A7I2V429_HUMAN,tr|A0A7I2V2W0|A0A7I2V2W0_HUMAN,tr|A0A161SXE1|A0A161SXE1_HUMAN" 17 1262.6962 1.15 27403 10613 2 1262.695096 632.3554 Eukaryotic translation initiation factor 3 subunit E OS=Homo sapiens OX=9606 GN=EIF3E PE=1 SV=1 4.53 2293.6 - 953091 - - - -0.8482 - 1.861 0.378 - 276.3 1 2 0 -0.0011 11 0 0 0 2.12E+08 1.84E+08 - - - 3.5128 0.9997 221125_WJC_METTL3_EV_vs_WT_F03.10617.10617.2 2.33E-06 20-Dec K.QLQAETEPIVK.M "sp|P60228|EIF3E_HUMAN,tr|A0A7I2V3I2|A0A7I2V3I2_HUMAN,tr|A0A7I2V570|A0A7I2V570_HUMAN,tr|A0A7I2V2Q9|A0A7I2V2Q9_HUMAN,tr|H0YBP5|H0YBP5_HUMAN,tr|A0A7I2V5Z6|A0A7I2V5Z6_HUMAN,tr|A0A7I2V2H9|A0A7I2V2H9_HUMAN,tr|B3KW56|B3KW56_HUMAN,tr|A0A7I2V4B4|A0A7I2V4B4_HUMAN,tr|A0A7I2V3I0|A0A7I2V3I0_HUMAN,tr|A0A7I2V3S3|A0A7I2V3S3_HUMAN,tr|A0A7I2V4G3|A0A7I2V4G3_HUMAN,tr|A0A7I2V3W9|A0A7I2V3W9_HUMAN,tr|H0YBR5|H0YBR5_HUMAN,tr|A0A7I2V429|A0A7I2V429_HUMAN,tr|A0A7I2V2W0|A0A7I2V2W0_HUMAN,tr|A0A161SXE1|A0A161SXE1_HUMAN" 17 1254.682 1.15 27405 10617 2 1254.680047 628.3483 Eukaryotic translation initiation factor 3 subunit E OS=Homo sapiens OX=9606 GN=EIF3E PE=1 SV=1 4.53 2294.1 - 1.06E+06 - - - -1.5303 - 2.137 0.425 - 581.8 1 2 0 -0.0019 11 0 0 0 2.12E+08 1.85E+08 - - - 4.2338 0.959 221125_WJC_METTL3_EV_vs_WT_F03.10618.10618.2 0.021 12-Jul G.TTTLAFK[136.11].F "sp|P28074|PSB5_HUMAN,sp|P28062|PSB8_HUMAN,tr|X5D2R7|X5D2R7_HUMAN,tr|G8JLC2|G8JLC2_HUMAN,tr|Q5JNW7|Q5JNW7_HUMAN,tr|A0A140T998|A0A140T998_HUMAN,tr|H0YJM8|H0YJM8_HUMAN,tr|G3V3K3|G3V3K3_HUMAN" 8 788.4524 0.68 27406 10618 2 788.452384 395.2335 Proteasome subunit beta type-5 OS=Homo sapiens OX=9606 GN=PSMB5 PE=1 SV=3 8.41 2294.3 - 815532 - - - 0.0368 - 1.556 0.303 - 194.4 1 1 0 0 7 0 0 0 4.02E+07 5.88E+07 - - - 2.6798 0.9778 221125_WJC_METTL3_EV_vs_WT_F03.10620.10620.2 0.591 14-Jun K.DLEGLSQR[166.11].H sp|P35579|MYH9_HUMAN 1 926.4697 1 27407 10620 2 926.468386 464.2421 Myosin-9 OS=Homo sapiens OX=9606 GN=MYH9 PE=1 SV=4 4.37 2294.5 - 1.43E+07 - - - -1.3967 - 1.109 0.133 - 123.4 1 2 0 -0.0013 8 0 0 0 5.01E+08 5.01E+08 - - - 0.335 0.9987 221125_WJC_METTL3_EV_vs_WT_F03.10625.10625.2 0.187 18-Oct K.ILTATIENNR.V "sp|P13646|K1C13_HUMAN,tr|K7EMD9|K7EMD9_HUMAN,tr|K7ERE3|K7ERE3_HUMAN" 3 1143.6248 999 27409 10625 2 1143.621823 572.8197 "Keratin, type I cytoskeletal 13 OS=Homo sapiens OX=9606 GN=KRT13 PE=1 SV=4" 6 2295.1 - 2.01E+07 - - - -2.5918 - 2.103 0.291 - 346.3 1 2 0 -0.003 10 0 0 0 8.56E+08 0.00E+00 - - - 3.2644 0.9994 221125_WJC_METTL3_EV_vs_WT_F03.10630.10630.2 0.0244 16-Jul K.ISSVSEVMK[136.11].E "sp|Q16891|MIC60_HUMAN,tr|B9A067|B9A067_HUMAN,tr|A0A087WYS0|A0A087WYS0_HUMAN,tr|D6RAW4|D6RAW4_HUMAN,tr|C9J406|C9J406_HUMAN,tr|H7C463|H7C463_HUMAN" 6 986.5198 1.02 27412 10630 2 986.518437 494.2672 MICOS complex subunit MIC60 OS=Homo sapiens OX=9606 GN=IMMT PE=1 SV=1 6 2295.7 - 5.36E+06 - - - -1.3644 - 1.801 0.329 - 94.1 1 2 0 -0.0013 9 0 0 0 8.83E+08 8.62E+08 - - - 3.1727 0.9989 221125_WJC_METTL3_EV_vs_WT_F03.10632.10632.2 0.337 14-Aug K.QLIVGVNK[136.11].M "sp|Q05639|EF1A2_HUMAN,sp|P68104|EF1A1_HUMAN,sp|Q5VTE0|EF1A3_HUMAN,sp|P06276|CHLE_HUMAN,tr|A0A2R8Y488|A0A2R8Y488_HUMAN,tr|A0A7I2V659|A0A7I2V659_HUMAN,tr|A0A7I2V3H3|A0A7I2V3H3_HUMAN,tr|F8WF14|F8WF14_HUMAN,tr|A0A2U3TZH3|A0A2U3TZH3_HUMAN,tr|A0A7I2V5N4|A0A7I2V5N4_HUMAN,tr|A0A087WVQ9|A0A087WVQ9_HUMAN,tr|A0A087WV01|A0A087WV01_HUMAN,tr|F8WEX7|F8WEX7_HUMAN" 13 877.5477 0.37 27413 10632 2 877.545967 439.7811 Elongation factor 1-alpha 2 OS=Homo sapiens OX=9606 GN=EEF1A2 PE=1 SV=1 8.75 2295.9 - 1.07E+08 - - - -1.9201 - 1.455 0.375 - 206.8 1 2 0 -0.0017 8 0 0 0 2.78E+09 7.54E+09 - - - 2.9412 0.9928 221125_WJC_METTL3_EV_vs_WT_F03.10639.10639.2 0.153 12-Jun K.EYIQQLR[166.11].S "sp|Q9NWU5|RM22_HUMAN,sp|Q9P2P6|STAR9_HUMAN,tr|E7ESL0|E7ESL0_HUMAN,tr|J3KQY1|J3KQY1_HUMAN" 4 958.5112 1.64 27417 10639 2 958.509396 480.2629 "39S ribosomal protein L22, mitochondrial OS=Homo sapiens OX=9606 GN=MRPL22 PE=1 SV=1" 6.1 2296.7 - 3.55E+06 - - - -1.831 - 1.331 0.185 - 172.3 1 2 0 -0.0018 7 0 0 0 2.86E+08 1.74E+08 - - - 1.3128 0.9999 221125_WJC_METTL3_EV_vs_WT_F03.10640.10640.2 8.71E-05 20-Dec R.VVGALASQDYR.V sp|P0C7T5|ATX1L_HUMAN 1 1177.6091 1.84 27418 10640 2 1177.607561 589.8118 Ataxin-1-like OS=Homo sapiens OX=9606 GN=ATXN1L PE=1 SV=1 5.81 2296.7 - 3.22E+06 - - - -1.3383 - 2.347 0.533 - 546.8 1 2 0 -0.0016 11 0 0 0 1.51E+08 8.22E+07 - - - 5.2852 0.9998 221125_WJC_METTL3_EV_vs_WT_F03.10641.10641.2 0.00277 18-Nov R.EMEAELEDER.K sp|P35579|MYH9_HUMAN 1 1249.5132 1.14 27419 10641 2 1249.511187 625.7639 Myosin-9 OS=Homo sapiens OX=9606 GN=MYH9 PE=1 SV=4 3.83 2296.9 - 891319 - - - -1.6486 - 2.056 0.483 - 623.4 1 2 0 -0.0021 10 0 0 0 2.41E+07 2.11E+07 - - - 4.6197 0.9287 221125_WJC_METTL3_EV_vs_WT_F03.10643.10643.2 3.04 12-Jul R.FSGVPDR.F "sp|A0A075B6R9|KVD24_HUMAN,sp|A0A0C4DH68|KV224_HUMAN,sp|A2NJV5|KV229_HUMAN,sp|A0A075B6S2|KVD29_HUMAN,sp|A0A0A0MRZ7|KVD26_HUMAN" 5 776.3817 19.36 27420 10643 2 776.379718 389.1981 Probable non-functional immunoglobulin kappa variable 2D-24 OS=Homo sapiens OX=9606 GN=IGKV2D-24 PE=1 SV=1 5.84 2297.1 - 1.09E+06 - - - -2.5567 - 1.272 0.035 - 130.3 1 2 0 -0.002 7 0 0 0 2.21E+08 1.14E+07 - - - 0.0612 0.9986 221125_WJC_METTL3_EV_vs_WT_F03.10645.10645.2 0.00344 16-Sep K.TIAEQLAEK.L "sp|Q7L014|DDX46_HUMAN,tr|A0A0C4DG89|A0A0C4DG89_HUMAN" 2 1001.5393 1.86 27421 10645 2 1001.537632 501.7769 Probable ATP-dependent RNA helicase DDX46 OS=Homo sapiens OX=9606 GN=DDX46 PE=1 SV=2 4.53 2297.3 - 4.16E+06 - - - -1.6914 - 1.65 0.281 - 177.1 1 2 0 -0.0017 9 0 0 0 2.23E+08 1.20E+08 - - - 2.5647 0.9997 221125_WJC_METTL3_EV_vs_WT_F03.10650.10650.2 7.59E-05 20-Dec R.VVGALASQDYR[166.11].V sp|P0C7T5|ATX1L_HUMAN 1 1187.6174 1.84 27424 10650 2 1187.614974 594.816 Ataxin-1-like OS=Homo sapiens OX=9606 GN=ATXN1L PE=1 SV=1 5.81 2297.8 - 2.43E+06 - - - -2.0486 - 2.122 0.475 - 520.5 1 2 0 -0.0024 11 0 0 0 1.51E+08 8.19E+07 - - - 4.5839 0.9939 221125_WJC_METTL3_EV_vs_WT_F03.10651.10651.2 0.0182 14-Jul R.INVELSTK[136.11].G sp|Q96PK6|RBM14_HUMAN 1 910.5215 1.76 27425 10651 2 910.519849 456.268 RNA-binding protein 14 OS=Homo sapiens OX=9606 GN=RBM14 PE=1 SV=2 6 2297.8 - 8.31E+06 - - - -1.81 - 1.704 0.123 - 134.8 2 2 0 -0.0016 8 0 0 0 4.19E+09 2.38E+09 - - - 1.4219 0.9291 221125_WJC_METTL3_EV_vs_WT_F03.10653.10653.2 0.00998 12-Jul G.TTTLAFK.F "sp|P28074|PSB5_HUMAN,sp|P28062|PSB8_HUMAN,tr|X5D2R7|X5D2R7_HUMAN,tr|G8JLC2|G8JLC2_HUMAN,tr|Q5JNW7|Q5JNW7_HUMAN,tr|A0A140T998|A0A140T998_HUMAN,tr|H0YJM8|H0YJM8_HUMAN,tr|G3V3K3|G3V3K3_HUMAN" 8 780.4382 0.67 27427 10653 2 780.436705 391.2264 Proteasome subunit beta type-5 OS=Homo sapiens OX=9606 GN=PSMB5 PE=1 SV=3 8.41 2298 - 1.79E+06 - - - -1.8579 - 1.44 0.348 - 278.2 1 1 0 -0.0014 7 0 0 0 3.92E+07 5.83E+07 - - - 2.7663 0.9993 221125_WJC_METTL3_EV_vs_WT_F03.10656.10656.2 0.026 14-Aug K.QLIVGVNK.M "sp|Q05639|EF1A2_HUMAN,sp|P68104|EF1A1_HUMAN,sp|Q5VTE0|EF1A3_HUMAN,sp|P06276|CHLE_HUMAN,tr|A0A2R8Y488|A0A2R8Y488_HUMAN,tr|A0A7I2V659|A0A7I2V659_HUMAN,tr|A0A7I2V3H3|A0A7I2V3H3_HUMAN,tr|F8WF14|F8WF14_HUMAN,tr|A0A2U3TZH3|A0A2U3TZH3_HUMAN,tr|A0A7I2V5N4|A0A7I2V5N4_HUMAN,tr|A0A087WVQ9|A0A087WVQ9_HUMAN,tr|A0A087WV01|A0A087WV01_HUMAN,tr|F8WEX7|F8WEX7_HUMAN" 13 869.5335 0.37 27428 10656 2 869.532387 435.774 Elongation factor 1-alpha 2 OS=Homo sapiens OX=9606 GN=EEF1A2 PE=1 SV=1 8.75 2298.3 - 8.24E+07 - - - -1.2248 - 1.527 0.354 - 189.2 1 2 0 -0.0011 8 0 0 0 2.78E+09 7.54E+09 - - - 2.932 0.9987 221125_WJC_METTL3_EV_vs_WT_F03.10657.10657.2 0.00918 16-Jul K.TTLTAAITK.L "sp|P49411|EFTU_HUMAN,tr|H3BNU3|H3BNU3_HUMAN" 2 918.5386 1.46 27429 10657 2 918.536913 460.2766 "Elongation factor Tu, mitochondrial OS=Homo sapiens OX=9606 GN=TUFM PE=1 SV=2" 8.41 2298.4 - 1.20E+07 - - - -1.8333 - 1.589 0.321 - 178.1 1 2 0 -0.0017 9 0 0 0 1.08E+09 7.38E+08 - - - 2.7512 0.9998 221125_WJC_METTL3_EV_vs_WT_F03.10659.10659.2 0.000862 16-Dec K.TGTVSLEVR[166.11].L "sp|P49327|FAS_HUMAN,tr|A0A0U1RQF0|A0A0U1RQF0_HUMAN" 2 970.5323 0.59 27431 10659 2 970.53073 486.2734 Fatty acid synthase OS=Homo sapiens OX=9606 GN=FASN PE=1 SV=3 5.66 2298.5 - 1.51E+06 - - - -1.5971 - 2.56 0.388 - 662.2 1 2 0 -0.0015 9 0 0 0 1.01E+08 1.71E+08 - - - 4.6258 0.9832 221125_WJC_METTL3_EV_vs_WT_F03.10664.10664.2 2.13 14-Jul K.NLEELEEK[136.11].S "sp|Q9UN86|G3BP2_HUMAN,tr|A0A7I2V3E2|A0A7I2V3E2_HUMAN,tr|A0A7I2V647|A0A7I2V647_HUMAN,tr|A0A7I2YQS2|A0A7I2YQS2_HUMAN,tr|A0A7I2YQD9|A0A7I2YQD9_HUMAN,tr|A0A7I2V3P9|A0A7I2V3P9_HUMAN" 6 1010.5012 1.55 27433 10664 2 1010.499866 506.2579 Ras GTPase-activating protein-binding protein 2 OS=Homo sapiens OX=9606 GN=G3BP2 PE=1 SV=2 4.09 2299.1 - 4.34E+06 - - - -1.2766 - 1.261 0.1 - 139.7 1 2 0 -0.0013 8 0 0 0 1.15E+09 7.46E+08 - - - 0.4786 0.9943 221125_WJC_METTL3_EV_vs_WT_F03.10670.10670.2 0.171 14-Jul K.NLEELEEK.S "sp|Q9UN86|G3BP2_HUMAN,tr|A0A7I2V3E2|A0A7I2V3E2_HUMAN,tr|A0A7I2V647|A0A7I2V647_HUMAN,tr|A0A7I2YQS2|A0A7I2YQS2_HUMAN,tr|A0A7I2YQD9|A0A7I2YQD9_HUMAN,tr|A0A7I2V3P9|A0A7I2V3P9_HUMAN" 6 1002.487 1.55 27436 10670 2 1002.485282 502.2508 Ras GTPase-activating protein-binding protein 2 OS=Homo sapiens OX=9606 GN=G3BP2 PE=1 SV=2 4.09 2299.9 - 1.02E+07 - - - -1.6698 - 1.45 0.168 - 143.4 1 2 0 -0.0017 8 0 0 0 1.15E+09 7.46E+08 - - - 1.4019 0.9995 221125_WJC_METTL3_EV_vs_WT_F03.10673.10673.2 0.00051 14-Aug K.NGDYLC[160.03]VK.V sp|P55884|EIF3B_HUMAN 1 967.4433 1.14 27439 10673 2 967.44178 484.7289 Eukaryotic translation initiation factor 3 subunit B OS=Homo sapiens OX=9606 GN=EIF3B PE=1 SV=3 5.83 2300.2 - 1.41E+06 - - - -1.5887 - 1.673 0.407 - 260.2 1 2 0 -0.0015 8 0 0 0 4.37E+07 3.82E+07 - - - 3.5987 0.9959 221125_WJC_METTL3_EV_vs_WT_F03.10674.10674.2 0.051 14-Aug K.AALSLPAK[136.11].Q "sp|Q14978|NOLC1_HUMAN,tr|A0A0A0MRM9|A0A0A0MRM9_HUMAN" 2 777.484 1.88 27440 10674 2 777.482425 389.7493 Nucleolar and coiled-body phosphoprotein 1 OS=Homo sapiens OX=9606 GN=NOLC1 PE=1 SV=2 8.8 2300.3 - 1.37E+06 - - - -2.0129 - 1.506 0.211 - 197.9 1 2 0 -0.0016 8 0 0 0 1.04E+09 5.51E+08 - - - 1.8339 0.999 221125_WJC_METTL3_EV_vs_WT_F03.10678.10678.2 0.00155 16-Aug K.TTLTAAITK[136.11].L "sp|P49411|EFTU_HUMAN,tr|H3BNU3|H3BNU3_HUMAN" 2 926.5528 1.47 27442 10678 2 926.551304 464.2837 "Elongation factor Tu, mitochondrial OS=Homo sapiens OX=9606 GN=TUFM PE=1 SV=2" 8.41 2300.8 - 2.00E+07 - - - -1.6113 - 1.711 0.307 - 239.3 1 2 0 -0.0015 9 0 0 0 1.08E+09 7.40E+08 - - - 2.8618 0.9483 221125_WJC_METTL3_EV_vs_WT_F03.10680.10680.2 0.0295 14-Sep V.PQQIEVAR.Q sp|Q96I24|FUBP3_HUMAN 1 939.5138 1.1 27444 10680 2 939.51232 470.7642 Far upstream element-binding protein 3 OS=Homo sapiens OX=9606 GN=FUBP3 PE=1 SV=2 6.43 2300.9 - 4.31E+06 - - - -1.554 - 1.935 0.253 - 357.7 1 1 0 -0.0015 8 0 0 0 1.64E+08 1.49E+08 - - - 2.9001 0.9992 221125_WJC_METTL3_EV_vs_WT_F03.10687.10687.2 0.0727 14-Aug K.SLEATLGR.L sp|Q92665|RT31_HUMAN 1 845.4607 1.51 27447 10687 2 845.461105 423.7376 "28S ribosomal protein S31, mitochondrial OS=Homo sapiens OX=9606 GN=MRPS31 PE=1 SV=3" 5.72 2301.8 - 5.71E+06 - - - 0.5015 - 1.667 0.286 - 218.3 1 2 0 0.0004 8 0 0 0 3.13E+08 2.07E+08 - - - 2.6945 0.9994 221125_WJC_METTL3_EV_vs_WT_F03.10689.10689.2 0.00292 16-Oct K.C[160.03]EVLQYSAR.E "sp|O95299|NDUAA_HUMAN,tr|A0A7I2V4N8|A0A7I2V4N8_HUMAN,tr|A0A7I2V2N6|A0A7I2V2N6_HUMAN,tr|H7C1Y7|H7C1Y7_HUMAN,tr|A0A7I2V5B2|A0A7I2V5B2_HUMAN,tr|A0A7I2V419|A0A7I2V419_HUMAN,tr|A0A7I2V2W9|A0A7I2V2W9_HUMAN,tr|A0A7I2V2X3|A0A7I2V2X3_HUMAN,tr|H7C2W5|H7C2W5_HUMAN,tr|A0A7I2YQU0|A0A7I2YQU0_HUMAN,tr|H7C2X4|H7C2X4_HUMAN,tr|A0A7I2V438|A0A7I2V438_HUMAN,tr|E7ESZ7|E7ESZ7_HUMAN,tr|A0A7I2V5L0|A0A7I2V5L0_HUMAN,tr|A0A087WXC5|A0A087WXC5_HUMAN,tr|A0A7I2V458|A0A7I2V458_HUMAN,tr|A0A7I2V594|A0A7I2V594_HUMAN,tr|A0A7I2V327|A0A7I2V327_HUMAN,tr|A0A7I2V5U7|A0A7I2V5U7_HUMAN" 19 1124.5284 2.29 27449 10689 2 1124.525786 563.2715 "NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 10, mitochondrial OS=Homo sapiens OX=9606 GN=NDUFA10 PE=1 SV=1" 5.99 2302 - 931444 - - - -2.3637 - 2.136 0.373 - 439.7 1 2 0 -0.0027 9 0 0 0 6.89E+07 3.01E+07 - - - 3.9908 0.9887 221125_WJC_METTL3_EV_vs_WT_F03.10692.10692.2 1.56 12-Jul K.NLIQSVR[166.11].N sp|O75446|SAP30_HUMAN 1 838.49 0.67 27450 10692 2 838.490191 420.2523 Histone deacetylase complex subunit SAP30 OS=Homo sapiens OX=9606 GN=SAP30 PE=1 SV=1 9.75 2302.4 - 2.21E+06 - - - 0.2027 - 1.384 0.065 - 238.3 1 2 0 0.0002 7 0 0 0 4.75E+07 7.04E+07 - - - 0.5507 0.9707 221125_WJC_METTL3_EV_vs_WT_F03.10694.10694.2 0.0358 16-Sep R.LASYLDKVR.A "sp|Q04695|K1C17_HUMAN,sp|Q99456|K1C12_HUMAN,sp|P13645|K1C10_HUMAN,sp|P02533|K1C14_HUMAN,sp|P08727|K1C19_HUMAN,sp|P08779|K1C16_HUMAN,sp|P19012|K1C15_HUMAN,tr|K7EPJ9|K7EPJ9_HUMAN,tr|C9JM50|C9JM50_HUMAN,tr|A0A1B0GVI3|A0A1B0GVI3_HUMAN,tr|A0A3B3ITG2|A0A3B3ITG2_HUMAN" 11 1063.6026 999 27452 10694 2 1063.60024 532.8086 "Keratin, type I cytoskeletal 17 OS=Homo sapiens OX=9606 GN=KRT17 PE=1 SV=2" 8.59 2302.5 - 1.09E+07 - - - -2.2142 - 1.907 0.19 - 377.7 1 2 1 -0.0024 9 0 0 0 2.18E+08 0.00E+00 - - - 2.3112 0.9977 221125_WJC_METTL3_EV_vs_WT_F03.10697.10697.2 0.0649 20-Aug R.GTGIVSAPVPK[136.11].K "sp|P15880|RS2_HUMAN,tr|I3L404|I3L404_HUMAN,tr|E9PM36|E9PM36_HUMAN,tr|E9PQD7|E9PQD7_HUMAN,tr|E9PMM9|E9PMM9_HUMAN,tr|H0YEN5|H0YEN5_HUMAN" 6 1032.6059 1.1 27454 10697 2 1032.60409 517.3102 40S ribosomal protein S2 OS=Homo sapiens OX=9606 GN=RPS2 PE=1 SV=2 8.75 2302.8 - 1.37E+07 - - - -1.749 - 1.541 0.263 - 212.5 1 2 0 -0.0018 11 0 0 0 1.37E+09 1.25E+09 - - - 2.1528 0.996 221125_WJC_METTL3_EV_vs_WT_F03.10701.10701.2 0.0932 18-Aug R.LGDYQTQLEK.L sp|P46939|UTRN_HUMAN 1 1193.5928 3.81 27457 10701 2 1193.591601 597.8037 Utrophin OS=Homo sapiens OX=9606 GN=UTRN PE=1 SV=2 4.37 2303.2 - 508610 - - - -1.0196 - 1.475 0.173 - 170.2 1 2 0 -0.0012 10 0 0 0 6.36E+06 1.67E+06 - - - 1.4033 0.9542 221125_WJC_METTL3_EV_vs_WT_F03.10704.10704.2 3.06 12-Jul K.NLIQSVR.N sp|O75446|SAP30_HUMAN 1 828.4818 0.59 27458 10704 2 828.479675 415.2482 Histone deacetylase complex subunit SAP30 OS=Homo sapiens OX=9606 GN=SAP30 PE=1 SV=1 9.75 2303.6 - 1.53E+06 - - - -2.5058 - 1.344 0.049 - 193.7 1 2 0 -0.0021 7 0 0 0 4.08E+07 6.91E+07 - - - 0.339 0.9996 221125_WJC_METTL3_EV_vs_WT_F03.10705.10705.2 0.00155 20-Nov K.VVVLGSGGVGK[136.11].S "sp|P10114|RAP2A_HUMAN,sp|P61225|RAP2B_HUMAN,sp|Q9Y3L5|RAP2C_HUMAN,tr|F6U784|F6U784_HUMAN" 4 978.5953 1.29 27459 10705 2 978.593038 490.3049 Ras-related protein Rap-2a OS=Homo sapiens OX=9606 GN=RAP2A PE=1 SV=1 8.72 2303.6 - 1.66E+06 - - - -2.3432 - 2.083 0.477 - 408.6 1 2 0 -0.0023 11 0 0 0 5.04E+07 3.91E+07 - - - 4.5485 0.9981 221125_WJC_METTL3_EV_vs_WT_F03.10706.10706.2 0.00073 16-Sep K.NVEDFTGPR[166.11].E sp|P61009|SPCS3_HUMAN 1 1043.4911 8.84 27460 10706 2 1043.491253 522.7528 Signal peptidase complex subunit 3 OS=Homo sapiens OX=9606 GN=SPCS3 PE=1 SV=1 4.37 2303.8 - 1.79E+06 - - - 0.1054 - 1.401 0.244 - 156.1 1 2 0 0.0001 9 0 0 0 9.36E+08 1.06E+08 - - - 1.8186 0.9951 221125_WJC_METTL3_EV_vs_WT_F03.10707.10707.2 0.0697 14-Jul R.AAALEQFK[136.11].S "sp|Q13423|NNTM_HUMAN,tr|E9PCX7|E9PCX7_HUMAN,tr|A0A590UK15|A0A590UK15_HUMAN,tr|A0A590UJM2|A0A590UJM2_HUMAN,tr|A0A590UK29|A0A590UK29_HUMAN,tr|A0A590UJI3|A0A590UJI3_HUMAN" 6 884.4847 2.12 27461 10707 2 884.482336 443.2496 "NAD(P) transhydrogenase, mitochondrial OS=Homo sapiens OX=9606 GN=NNT PE=1 SV=3" 6.05 2303.8 - 1.52E+06 - - - -2.6931 - 1.527 0.24 - 150.7 1 2 0 -0.0024 8 0 0 0 8.79E+07 4.16E+07 - - - 2.0896 0.8353 221125_WJC_METTL3_EV_vs_WT_F03.10708.10708.2 4.85 12-Jun R.SSIMDVR.S "sp|Q969V3|NCLN_HUMAN,tr|K7EMW4|K7EMW4_HUMAN,tr|K7ELZ9|K7ELZ9_HUMAN,tr|K7ENM2|K7ENM2_HUMAN,tr|K7EQ66|K7EQ66_HUMAN,tr|A0A0C4DGP7|A0A0C4DGP7_HUMAN" 6 806.3956 1.04 27462 10708 2 806.39334 404.2051 Nicalin OS=Homo sapiens OX=9606 GN=NCLN PE=1 SV=2 5.55 2304 - 427313 - - - -2.8497 - 1.022 0.067 - 126.2 1 2 0 -0.0023 7 0 0 0 1.32E+07 1.27E+07 - - - -0.3959 0.9994 221125_WJC_METTL3_EV_vs_WT_F03.10711.10711.2 0.00551 16-Sep R.QTVAVGVIK.N "sp|Q05639|EF1A2_HUMAN,sp|P68104|EF1A1_HUMAN,sp|Q5VTE0|EF1A3_HUMAN,tr|A0A7I2V659|A0A7I2V659_HUMAN,tr|A0A2U3TZH3|A0A2U3TZH3_HUMAN,tr|A0A087WVQ9|A0A087WVQ9_HUMAN" 6 913.5597 0.36 27463 10711 2 913.558059 457.7871 Elongation factor 1-alpha 2 OS=Homo sapiens OX=9606 GN=EEF1A2 PE=1 SV=1 8.75 2304.4 - 7.17E+07 - - - -1.7601 - 1.73 0.394 - 340.9 1 2 0 -0.0016 9 0 0 0 4.51E+09 1.26E+10 - - - 3.5363 0.9879 221125_WJC_METTL3_EV_vs_WT_F03.10715.10715.2 0.325 20-Aug K.MSPPPSGFGER[166.11].S "tr|K7EQG2|K7EQG2_HUMAN,tr|E9PAU2|E9PAU2_HUMAN,tr|A0A087WZ13|A0A087WZ13_HUMAN" 3 1170.5367 0.68 27467 10715 2 1170.535303 586.2756 Uncharacterized protein (Fragment) OS=Homo sapiens OX=9606 PE=1 SV=1 5.75 2304.7 - 884232 - - - -1.2046 - 1.069 0.197 - 121.3 1 2 0 -0.0014 11 0 0 0 6.27E+07 9.26E+07 - - - 0.6761 0.9895 221125_WJC_METTL3_EV_vs_WT_F03.10716.10716.2 0.18 18-Jul K.LFNPPEESEK[136.11].- "sp|Q9NRP2|COXM2_HUMAN,tr|H3BPP2|H3BPP2_HUMAN" 2 1196.5805 1.98 27468 10716 2 1196.583798 599.2975 COX assembly mitochondrial protein 2 homolog OS=Homo sapiens OX=9606 GN=CMC2 PE=1 SV=1 4.25 2304.9 - 442578 - - - 2.7821 - 1.241 0.26 - 144.5 1 2 0 0.0033 10 0 0 0 2.38E+07 1.20E+07 - - - 1.563 0.9986 221125_WJC_METTL3_EV_vs_WT_F03.10727.10727.2 0.0182 14-Jul K.VIPELNGK.L "sp|P04406|G3P_HUMAN,tr|E7EUT5|E7EUT5_HUMAN" 2 868.5018 1.06 27474 10727 2 868.501045 435.2582 Glyceraldehyde-3-phosphate dehydrogenase OS=Homo sapiens OX=9606 GN=GAPDH PE=1 SV=3 5.97 2306.2 - 3.13E+07 - - - -0.89 - 1.113 0.38 - 184.5 1 2 0 -0.0008 8 0 0 0 2.03E+10 1.92E+10 - - - 2.1703 0.9998 221125_WJC_METTL3_EV_vs_WT_F03.10728.10728.2 7.08E-05 18-Oct R.VQEAVESMVK.S "sp|Q96C01|F136A_HUMAN,tr|C9J2Y4|C9J2Y4_HUMAN,tr|E7EQY1|E7EQY1_HUMAN" 3 1118.5642 4.74 27475 10728 2 1118.562354 560.2894 Protein FAM136A OS=Homo sapiens OX=9606 GN=FAM136A PE=1 SV=1 4.53 2306.2 - 1.85E+06 - - - -1.6146 - 2.041 0.487 - 421.2 1 2 0 -0.0018 10 0 0 0 9.97E+07 2.10E+07 - - - 4.6288 0.9991 221125_WJC_METTL3_EV_vs_WT_F03.10729.10729.2 0.00267 14-Aug K.LLLDQEQK.K sp|O75937|DNJC8_HUMAN 1 985.5444 0.47 27476 10729 2 985.543176 493.7795 DnaJ homolog subfamily C member 8 OS=Homo sapiens OX=9606 GN=DNAJC8 PE=1 SV=2 4.37 2306.3 - 3.08E+06 - - - -1.2531 - 1.692 0.29 - 161.8 1 2 0 -0.0012 8 0 0 0 7.31E+07 1.55E+08 - - - 2.7687 0.9638 221125_WJC_METTL3_EV_vs_WT_F03.10730.10730.2 0.206 12-Jul R.SSIMDVR[166.11].S "sp|Q969V3|NCLN_HUMAN,tr|K7EMW4|K7EMW4_HUMAN,tr|K7ELZ9|K7ELZ9_HUMAN,tr|K7ENM2|K7ENM2_HUMAN,tr|K7EQ66|K7EQ66_HUMAN,tr|A0A0C4DGP7|A0A0C4DGP7_HUMAN" 6 816.4039 1.04 27477 10730 2 816.400928 409.2092 Nicalin OS=Homo sapiens OX=9606 GN=NCLN PE=1 SV=2 5.55 2306.5 - 1.16E+06 - - - -3.6502 - 1.425 0.124 - 157.7 1 2 0 -0.003 7 0 0 0 1.32E+07 1.27E+07 - - - 1.0781 0.9989 221125_WJC_METTL3_EV_vs_WT_F03.10731.10731.2 1.09E-05 20-Dec K.AAYEAELGDAR[166.11].K "sp|P02545|LMNA_HUMAN,tr|A0A6Q8PF80|A0A6Q8PF80_HUMAN,tr|A0A804HL68|A0A804HL68_HUMAN,tr|A0A6Q8PFM1|A0A6Q8PFM1_HUMAN,tr|A0A6Q8PF59|A0A6Q8PF59_HUMAN,tr|A0A6Q8PFJ0|A0A6Q8PFJ0_HUMAN,tr|A0A6Q8PHQ9|A0A6Q8PHQ9_HUMAN,tr|A0A6Q8PGH0|A0A6Q8PGH0_HUMAN,tr|Q3BDU5|Q3BDU5_HUMAN" 9 1174.5494 2.96 27478 10731 2 1174.544492 588.282 Prelamin-A\C OS=Homo sapiens OX=9606 GN=LMNA PE=1 SV=1 4.14 2306.6 - 863516 - - - -4.1676 - 2.054 0.558 - 406.2 1 2 0 -0.0049 11 0 0 0 6.19E+07 2.09E+07 - - - 5.1081 0.9958 221125_WJC_METTL3_EV_vs_WT_F03.10733.10733.2 0.255 16-Jul K.NVEDFTGPR.E sp|P61009|SPCS3_HUMAN 1 1033.4829 2.37 27479 10733 2 1033.482653 517.7487 Signal peptidase complex subunit 3 OS=Homo sapiens OX=9606 GN=SPCS3 PE=1 SV=1 4.37 2306.8 - 6.44E+06 - - - -0.2129 - 1.229 0.216 - 161.1 1 2 0 -0.0002 9 0 0 0 2.17E+08 9.16E+07 - - - 1.2329 0.9983 221125_WJC_METTL3_EV_vs_WT_F03.10734.10734.2 0.0369 14-Jul K.LLLDQEQK[136.11].K sp|O75937|DNJC8_HUMAN 1 993.5586 0.47 27480 10734 2 993.557013 497.7866 DnaJ homolog subfamily C member 8 OS=Homo sapiens OX=9606 GN=DNAJC8 PE=1 SV=2 4.37 2306.9 - 3.74E+06 - - - -1.6084 - 1.628 0.248 - 134.2 1 2 0 -0.0016 8 0 0 0 7.31E+07 1.55E+08 - - - 2.3421 0.9993 221125_WJC_METTL3_EV_vs_WT_F03.10735.10735.2 0.00764 14-Aug K.AALSLPAK.Q "sp|Q14978|NOLC1_HUMAN,tr|A0A0A0MRM9|A0A0A0MRM9_HUMAN" 2 769.4698 1.89 27481 10735 2 769.46829 385.7422 Nucleolar and coiled-body phosphoprotein 1 OS=Homo sapiens OX=9606 GN=NOLC1 PE=1 SV=2 8.8 2306.9 - 1.88E+07 - - - -1.9494 - 1.809 0.354 - 304.8 1 2 0 -0.0015 8 0 0 0 1.04E+09 5.51E+08 - - - 3.443 0.9766 221125_WJC_METTL3_EV_vs_WT_F03.10738.10738.2 0.00168 18-Sep L.SFETTDESLR[166.11].S "sp|Q32P51|RA1L2_HUMAN,sp|P09651|ROA1_HUMAN,tr|F8W646|F8W646_HUMAN,tr|F8VZ49|F8VZ49_HUMAN,tr|A0A7I2V3R8|A0A7I2V3R8_HUMAN,tr|F8VTQ5|F8VTQ5_HUMAN,tr|A0A7I2YQ85|A0A7I2YQ85_HUMAN,tr|F8W6I7|F8W6I7_HUMAN,tr|A0A7I2V2L6|A0A7I2V2L6_HUMAN,tr|A0A7I2V3W0|A0A7I2V3W0_HUMAN" 10 1193.544 1.26 27484 10738 2 1193.541411 597.7793 Heterogeneous nuclear ribonucleoprotein A1-like 2 OS=Homo sapiens OX=9606 GN=HNRNPA1L2 PE=2 SV=2 4.14 2307.1 - 1.07E+06 - - - -2.1415 - 2.016 0.452 - 206.6 1 1 0 -0.0026 10 0 0 0 1.92E+08 1.52E+08 - - - 4.3357 0.9985 221125_WJC_METTL3_EV_vs_WT_F03.10742.10742.2 0.134 14-Jul K.MTPSYEIR.A sp|Q08211|DHX9_HUMAN 1 995.4746 0.76 27486 10742 2 995.473675 498.7446 ATP-dependent RNA helicase A OS=Homo sapiens OX=9606 GN=DHX9 PE=1 SV=4 5.75 2307.6 - 2.86E+06 - - - -0.9463 - 1.287 0.318 - 134 1 2 0 -0.0009 8 0 0 0 1.86E+08 2.44E+08 - - - 2.1504 0.9909 221125_WJC_METTL3_EV_vs_WT_F03.10743.10743.2 0.0144 12-Aug K.SFEAPIK.L "sp|Q8TCT9|HM13_HUMAN,tr|A0A3B3IT72|A0A3B3IT72_HUMAN,tr|A0A0S2Z6F0|A0A0S2Z6F0_HUMAN,tr|A0A3B3IUB5|A0A3B3IUB5_HUMAN,tr|A0A075B6F6|A0A075B6F6_HUMAN" 5 790.4225 0.56 27487 10743 2 790.419631 396.2185 Minor histocompatibility antigen H13 OS=Homo sapiens OX=9606 GN=HM13 PE=1 SV=1 5.72 2307.8 - 1.92E+06 - - - -3.636 - 1.402 0.276 - 235.2 1 2 0 -0.0029 7 0 0 0 7.16E+07 1.28E+08 - - - 2.1493 0.9912 221125_WJC_METTL3_EV_vs_WT_F03.10744.10744.2 0.268 20-Sep K.ATILAGTANVK[136.11].V sp|Q8TBA6|GOGA5_HUMAN 1 1065.6274 2.15 27488 10744 2 1065.626014 533.821 Golgin subfamily A member 5 OS=Homo sapiens OX=9606 GN=GOLGA5 PE=1 SV=3 8.8 2307.8 - 1.85E+06 - - - -1.2622 - 1.508 0.103 - 176.6 1 2 0 -0.0013 11 0 0 0 1.04E+08 4.86E+07 - - - 0.9126 0.9998 221125_WJC_METTL3_EV_vs_WT_F03.10745.10745.2 7.87E-05 13/24 R.IIYGGSVTGATC[160.03]K[136.11].E sp|P60174|TPIS_HUMAN 1 1333.6791 1.45 27489 10745 2 1333.677614 667.8468 Triosephosphate isomerase OS=Homo sapiens OX=9606 GN=TPI1 PE=1 SV=4 8.2 2308 - 1.01E+06 - - - -1.142 - 1.998 0.462 - 232.2 1 2 0 -0.0015 13 0 0 0 4.80E+07 3.30E+07 - - - 4.2293 0.9961 221125_WJC_METTL3_EV_vs_WT_F03.10748.10748.2 0.000297 16-Sep R.EQAELTGLR[166.11].L sp|Q96HS1|PGAM5_HUMAN 1 1025.5381 1.28 27490 10748 2 1025.535923 513.7763 "Serine\threonine-protein phosphatase PGAM5, mitochondrial OS=Homo sapiens OX=9606 GN=PGAM5 PE=1 SV=2" 4.53 2308.4 - 2.67E+06 - - - -2.1169 - 1.682 0.19 - 426.8 1 2 0 -0.0022 9 0 0 0 3.63E+08 2.83E+08 - - - 1.948 0.8155 221125_WJC_METTL3_EV_vs_WT_F03.10751.10751.2 0.0221 16-Aug R.GPLPLSSQH.R "sp|P43243|MATR3_HUMAN,tr|A8MXP9|A8MXP9_HUMAN,tr|D6R991|D6R991_HUMAN,tr|A0A0R4J2E8|A0A0R4J2E8_HUMAN,tr|D6R8Z5|D6R8Z5_HUMAN,tr|D6REM6|D6REM6_HUMAN" 6 934.4872 - 27493 10751 2 934.485823 468.2509 Matrin-3 OS=Homo sapiens OX=9606 GN=MATR3 PE=1 SV=2 6.74 2308.6 - 1.78E+06 - - - -1.5067 - 1.432 0.212 - 203.9 1 1 0 -0.0014 9 0 0 0 - - - - - 1.6452 0.9878 221125_WJC_METTL3_EV_vs_WT_F03.10754.10754.2 0.00354 18-Sep L.SFETTDESLR.S "sp|Q32P51|RA1L2_HUMAN,sp|P09651|ROA1_HUMAN,tr|F8W646|F8W646_HUMAN,tr|F8VZ49|F8VZ49_HUMAN,tr|A0A7I2V3R8|A0A7I2V3R8_HUMAN,tr|F8VTQ5|F8VTQ5_HUMAN,tr|A0A7I2YQ85|A0A7I2YQ85_HUMAN,tr|F8W6I7|F8W6I7_HUMAN,tr|A0A7I2V2L6|A0A7I2V2L6_HUMAN,tr|A0A7I2V3W0|A0A7I2V3W0_HUMAN" 10 1183.5357 1.26 27494 10754 2 1183.534108 592.7751 Heterogeneous nuclear ribonucleoprotein A1-like 2 OS=Homo sapiens OX=9606 GN=HNRNPA1L2 PE=2 SV=2 4.14 2308.9 - 3.62E+06 - - - -1.3426 - 1.95 0.493 - 220.1 1 1 0 -0.0016 10 0 0 0 1.92E+08 1.52E+08 - - - 4.5459 1 221125_WJC_METTL3_EV_vs_WT_F03.10755.10755.2 2.98E-06 14/22 K.TPALANEEALQK.L "sp|Q15390|MTFR1_HUMAN,tr|H0YBZ4|H0YBZ4_HUMAN" 2 1283.6721 12.39 27495 10755 2 1283.670512 642.8433 Mitochondrial fission regulator 1 OS=Homo sapiens OX=9606 GN=MTFR1 PE=1 SV=2 4.53 2309.1 - 369893 - - - -1.2612 - 2.731 0.592 - 625.4 1 2 0 -0.0016 12 0 0 0 5.56E+06 4.49E+05 - - - 6.0565 0.9993 221125_WJC_METTL3_EV_vs_WT_F03.10756.10756.2 0.0137 14-Aug R.GLDVEDVK[136.11].F "sp|Q92841|DDX17_HUMAN,sp|P17844|DDX5_HUMAN,tr|A0A5H1ZRQ2|A0A5H1ZRQ2_HUMAN,tr|J3KTA4|J3KTA4_HUMAN,tr|A0A0G2JLI4|A0A0G2JLI4_HUMAN,tr|A0A1X7SBZ2|A0A1X7SBZ2_HUMAN" 6 881.4586 1.65 27496 10756 2 881.456977 441.7366 Probable ATP-dependent RNA helicase DDX17 OS=Homo sapiens OX=9606 GN=DDX17 PE=1 SV=2 4.03 2309.1 - 1.32E+07 - - - -1.7993 - 1.449 0.425 - 195.3 1 2 0 -0.0016 8 0 0 0 3.90E+09 2.36E+09 - - - 3.2981 0.9984 221125_WJC_METTL3_EV_vs_WT_F03.10765.10765.2 0.00188 20-Jul K.MSPPPSGFGER.S "tr|K7EQG2|K7EQG2_HUMAN,tr|E9PAU2|E9PAU2_HUMAN,tr|A0A087WZ13|A0A087WZ13_HUMAN" 3 1160.5284 0.63 27500 10765 2 1160.527362 581.2715 Uncharacterized protein (Fragment) OS=Homo sapiens OX=9606 PE=1 SV=1 5.75 2310.2 - 852704 - - - -0.9315 - 1.255 0.331 - 101 1 2 0 -0.0011 11 0 0 0 4.39E+07 6.93E+07 - - - 2.0999 0.9999 221125_WJC_METTL3_EV_vs_WT_F03.10769.10769.2 0.000392 13/22 R.LLSTDAEAVSTR.W sp|Q15545|TAF7_HUMAN 1 1261.6514 1.73 27502 10769 2 1261.650345 631.833 Transcription initiation factor TFIID subunit 7 OS=Homo sapiens OX=9606 GN=TAF7 PE=1 SV=1 4.37 2310.7 - 612450 - - - -0.8322 - 2.456 0.488 - 607 1 2 0 -0.001 12 0 0 0 2.58E+07 1.49E+07 - - - 5.0092 0.9997 221125_WJC_METTL3_EV_vs_WT_F03.10770.10770.2 0.00523 20-Dec R.GLGAIQPGVNR[166.11].C "sp|Q9UI36|DACH1_HUMAN,sp|Q96NX9|DACH2_HUMAN,tr|D6RFG7|D6RFG7_HUMAN,tr|D6REJ4|D6REJ4_HUMAN" 4 1090.6123 2.05 27503 10770 2 1090.61236 546.3134 Dachshund homolog 1 OS=Homo sapiens OX=9606 GN=DACH1 PE=1 SV=4 9.75 2310.8 - 680212 - - - 0.0899 - 2.222 0.335 - 446.1 1 2 0 0.0001 11 0 0 0 7.30E+08 3.57E+08 - - - 3.6752 0.9846 221125_WJC_METTL3_EV_vs_WT_F03.10771.10771.2 0.000281 20-Nov H.IMEDLDTNADK.Q sp|P06702|S10A9_HUMAN 1 1263.5653 999 27504 10771 2 1263.56365 632.7899 Protein S100-A9 OS=Homo sapiens OX=9606 GN=S100A9 PE=1 SV=1 3.84 2311 - 612450 - - - -1.2924 - 1.817 0.474 - 262.7 1 1 0 -0.0016 11 0 0 0 1.56E+07 0.00E+00 - - - 4.157 0.9494 221125_WJC_METTL3_EV_vs_WT_F03.10775.10775.3 0.00669 Sep-32 K.LMC[160.03]K[136.11]PIFSK[136.11].L sp|P41091|IF2G_HUMAN 1 1138.6214 0.001 27506 10775 3 1138.614365 380.5477 Eukaryotic translation initiation factor 2 subunit 3 OS=Homo sapiens OX=9606 GN=EIF2S3 PE=1 SV=3 9.31 2311.4 - 736748 - - - -6.1416 - 1.589 0.278 - 89.5 1 2 0 -0.007 9 0 0 0 0.00E+00 5.99E+07 - - - 3.0332 0.9993 221125_WJC_METTL3_EV_vs_WT_F03.10777.10777.2 0.00084 14-Jul K.DGVPIGYK.G "sp|O43447|PPIH_HUMAN,tr|A0A7I2V2H6|A0A7I2V2H6_HUMAN,tr|A0A7I2V343|A0A7I2V343_HUMAN,tr|A0A7I2YQS4|A0A7I2YQS4_HUMAN,tr|C9JQD4|C9JQD4_HUMAN" 5 847.444 1.97 27508 10777 2 847.442546 424.7293 Peptidyl-prolyl cis-trans isomerase H OS=Homo sapiens OX=9606 GN=PPIH PE=1 SV=1 5.83 2311.5 - 1.92E+07 - - - -1.6792 - 1.462 0.413 - 175.1 1 2 0 -0.0014 8 0 0 0 7.12E+08 3.61E+08 - - - 3.2364 0.9995 221125_WJC_METTL3_EV_vs_WT_F03.10781.10781.2 0.000938 16-Oct K.NVAVDELSR.Q "sp|P16083|NQO2_HUMAN,tr|Q5TD07|Q5TD07_HUMAN,tr|Q5TD05|Q5TD05_HUMAN,tr|A2A2U4|A2A2U4_HUMAN" 4 1001.5142 2 27509 10781 2 1001.51204 501.7644 Ribosyldihydronicotinamide dehydrogenase [quinone] OS=Homo sapiens OX=9606 GN=NQO2 PE=1 SV=5 4.37 2312.1 - 7.75E+06 - - - -2.1308 - 1.926 0.405 - 375.6 1 2 0 -0.0021 9 0 0 0 2.09E+08 1.04E+08 - - - 3.9279 0.9988 221125_WJC_METTL3_EV_vs_WT_F03.10782.10782.2 0.00288 22-Dec R.LLSTDAEAVSTR[166.11].W sp|Q15545|TAF7_HUMAN 1 1271.6597 1.73 27510 10782 2 1271.657498 636.8371 Transcription initiation factor TFIID subunit 7 OS=Homo sapiens OX=9606 GN=TAF7 PE=1 SV=1 4.37 2312.2 - 724639 - - - -1.7041 - 1.704 0.313 - 213.6 1 2 0 -0.0022 12 0 0 0 2.58E+07 1.49E+07 - - - 2.7545 0.9995 221125_WJC_METTL3_EV_vs_WT_F03.10785.10785.2 0.0103 18-Sep R.GVPQQIEVAR.Q sp|Q96I24|FUBP3_HUMAN 1 1095.6037 1.99 27512 10785 2 1095.602045 548.8091 Far upstream element-binding protein 3 OS=Homo sapiens OX=9606 GN=FUBP3 PE=1 SV=2 6 2312.5 - 3.30E+07 - - - -1.4713 - 1.635 0.405 - 382.9 1 2 0 -0.0016 10 0 0 0 1.74E+09 8.75E+08 - - - 3.4041 0.9997 221125_WJC_METTL3_EV_vs_WT_F03.10790.10790.2 0.00072 18-Sep K.MIDVAEPGQR[166.11].K "sp|Q14671|PUM1_HUMAN,tr|Q5T1Z8|Q5T1Z8_HUMAN,tr|H0YDK8|H0YDK8_HUMAN,tr|H0YEH2|H0YEH2_HUMAN,tr|Q5T1Z4|Q5T1Z4_HUMAN,tr|E9PR38|E9PR38_HUMAN" 6 1124.5524 2.3 27516 10790 2 1124.553905 563.2835 Pumilio homolog 1 OS=Homo sapiens OX=9606 GN=PUM1 PE=1 SV=3 4.37 2313.1 - 1.02E+06 - - - 1.3703 - 1.84 0.452 - 242.9 1 2 0 0.0015 10 0 0 0 6.95E+08 3.03E+08 - - - 4.081 0.9997 221125_WJC_METTL3_EV_vs_WT_F03.10795.10795.2 0.000868 14-Jul K.DGVPIGYK[136.11].G "sp|O43447|PPIH_HUMAN,tr|A0A7I2V2H6|A0A7I2V2H6_HUMAN,tr|A0A7I2V343|A0A7I2V343_HUMAN,tr|A0A7I2YQS4|A0A7I2YQS4_HUMAN,tr|C9JQD4|C9JQD4_HUMAN" 5 855.4582 2.44 27517 10795 2 855.457648 428.7364 Peptidyl-prolyl cis-trans isomerase H OS=Homo sapiens OX=9606 GN=PPIH PE=1 SV=1 5.83 2313.8 - 6.99E+06 - - - -0.609 - 1.472 0.457 - 159.1 1 2 0 -0.0005 8 0 0 0 7.08E+08 2.90E+08 - - - 3.5823 0.9975 221125_WJC_METTL3_EV_vs_WT_F03.10796.10796.2 0.0604 12-May R.NPDDVFR.E "sp|O75190|DNJB6_HUMAN,tr|C9JDX6|C9JDX6_HUMAN,tr|E9PH18|E9PH18_HUMAN,tr|A0A0J9YX62|A0A0J9YX62_HUMAN,tr|C9J2P2|C9J2P2_HUMAN,tr|C9J2C4|C9J2C4_HUMAN,tr|F8WCZ4|F8WCZ4_HUMAN" 7 861.3981 1.91 27518 10796 2 861.397801 431.7063 DnaJ homolog subfamily B member 6 OS=Homo sapiens OX=9606 GN=DNAJB6 PE=1 SV=2 4.21 2313.9 - 5.29E+06 - - - -0.3251 - 1.011 0.344 - 112.6 1 2 0 -0.0003 7 0 0 0 2.20E+08 1.15E+08 - - - 1.6164 0.9944 221125_WJC_METTL3_EV_vs_WT_F03.10799.10799.2 0.0036 18-Sep K.MIDVAEPGQR.K "sp|Q14671|PUM1_HUMAN,tr|Q5T1Z8|Q5T1Z8_HUMAN,tr|H0YDK8|H0YDK8_HUMAN,tr|H0YEH2|H0YEH2_HUMAN,tr|Q5T1Z4|Q5T1Z4_HUMAN,tr|E9PR38|E9PR38_HUMAN" 6 1114.5441 2.24 27519 10799 2 1114.538737 558.2793 Pumilio homolog 1 OS=Homo sapiens OX=9606 GN=PUM1 PE=1 SV=3 4.37 2314.3 - 5.57E+06 - - - -4.8064 - 1.96 0.342 - 305.7 1 2 0 -0.0054 10 0 0 0 6.79E+08 3.03E+08 - - - 3.4437 0.9997 221125_WJC_METTL3_EV_vs_WT_F03.10800.10800.2 0.000486 18-Sep K.LFNPPEESEK.- "sp|Q9NRP2|COXM2_HUMAN,tr|H3BPP2|H3BPP2_HUMAN" 2 1188.5663 1.93 27520 10800 2 1188.566813 595.2904 COX assembly mitochondrial protein 2 homolog OS=Homo sapiens OX=9606 GN=CMC2 PE=1 SV=1 4.25 2314.4 - 647376 - - - 0.4577 - 1.518 0.463 - 285.7 1 2 0 0.0005 10 0 0 0 7.32E+07 3.79E+07 - - - 3.6256 0.9993 221125_WJC_METTL3_EV_vs_WT_F03.10802.10802.2 0.119 14-Sep R.INVELSTK.G sp|Q96PK6|RBM14_HUMAN 1 902.5073 1.76 27521 10802 2 902.505488 452.2609 RNA-binding protein 14 OS=Homo sapiens OX=9606 GN=RBM14 PE=1 SV=2 6 2314.6 - 2.84E+07 - - - -2.0044 - 1.969 0.334 - 226.7 1 2 0 -0.0018 8 0 0 0 4.17E+09 2.37E+09 - - - 3.5507 0.9997 221125_WJC_METTL3_EV_vs_WT_F03.10804.10804.2 0.000579 14-Jul R.NNFAVGYR.T "sp|P45880|VDAC2_HUMAN,tr|Q5JSD1|Q5JSD1_HUMAN,tr|Q5JSD2|Q5JSD2_HUMAN,tr|A0A0A0MR02|A0A0A0MR02_HUMAN" 4 939.4563 1.46 27522 10804 2 939.455432 470.7354 Voltage-dependent anion-selective channel protein 2 OS=Homo sapiens OX=9606 GN=VDAC2 PE=1 SV=2 8.75 2314.8 - 4.05E+06 - - - -0.8867 - 1.715 0.436 - 214.4 1 2 0 -0.0008 8 0 0 0 5.79E+08 3.97E+08 - - - 3.8879 0.9532 221125_WJC_METTL3_EV_vs_WT_F03.10805.10805.2 0.0245 18-Oct A.VFPVAPTSSK.Q "sp|Q14157|UBP2L_HUMAN,tr|F8W726|F8W726_HUMAN,tr|H7C2T8|H7C2T8_HUMAN,tr|H0Y5H6|H0Y5H6_HUMAN" 4 1031.5651 1.77 27523 10805 2 1031.565908 516.7898 Ubiquitin-associated protein 2-like OS=Homo sapiens OX=9606 GN=UBAP2L PE=1 SV=2 8.72 2314.9 - 1.98E+06 - - - 0.7377 - 1.446 0.357 - 363.2 1 1 0 0.0008 10 0 0 0 1.68E+08 9.48E+07 - - - 2.707 0.9986 221125_WJC_METTL3_EV_vs_WT_F03.10806.10806.2 0.00173 14-Aug K.FNTTSVIK.L sp|Q15029|U5S1_HUMAN 1 908.4967 1.44 27524 10806 2 908.494685 455.2556 116 kDa U5 small nuclear ribonucleoprotein component OS=Homo sapiens OX=9606 GN=EFTUD2 PE=1 SV=1 8.75 2315 - 1.68E+07 - - - -2.2543 - 1.525 0.358 - 154.1 1 2 0 -0.002 8 0 0 0 4.17E+08 2.89E+08 - - - 2.9573 0.9959 221125_WJC_METTL3_EV_vs_WT_F03.10807.10807.2 0.0602 16-Aug -.MIEVVC[160.03]NDR.L "sp|Q9BZL1|UBL5_HUMAN,tr|K7EQ43|K7EQ43_HUMAN" 2 1134.5162 1.56 27525 10807 2 1134.514488 568.2654 Ubiquitin-like protein 5 OS=Homo sapiens OX=9606 GN=UBL5 PE=1 SV=1 4.37 2315.1 - 2.81E+06 - - - -1.4773 - 1.343 0.227 - 140.4 1 2 0 -0.0017 9 0 0 0 8.96E+08 5.74E+08 - - - 1.5703 1 221125_WJC_METTL3_EV_vs_WT_F03.10808.10808.2 6.95E-07 13/16 -.MIEVVC[160.03]NDR[166.11].L "sp|Q9BZL1|UBL5_HUMAN,tr|K7EQ43|K7EQ43_HUMAN" 2 1144.5244 1.56 27526 10808 2 1144.517981 573.2695 Ubiquitin-like protein 5 OS=Homo sapiens OX=9606 GN=UBL5 PE=1 SV=1 4.37 2315.2 - 1.18E+06 - - - -5.6381 - 2.392 0.578 - 591.1 1 2 0 -0.0065 9 0 0 0 8.96E+08 5.74E+08 - - - 5.8312 0.9988 221125_WJC_METTL3_EV_vs_WT_F03.10811.10811.2 0.017 14-Aug K.FNTTSVIK[136.11].L sp|Q15029|U5S1_HUMAN 1 916.5109 1.44 27527 10811 2 916.508197 459.2627 116 kDa U5 small nuclear ribonucleoprotein component OS=Homo sapiens OX=9606 GN=EFTUD2 PE=1 SV=1 8.75 2315.6 - 9.85E+06 - - - -2.9852 - 1.927 0.367 - 152.8 1 2 0 -0.0027 8 0 0 0 4.17E+08 2.89E+08 - - - 3.7292 0.9222 221125_WJC_METTL3_EV_vs_WT_F03.10814.10814.2 1.81 12-Jul -.MLTELEK.A sp|P05109|S10A8_HUMAN 1 862.447 999 27528 10814 2 862.446948 432.2308 Protein S100-A8 OS=Homo sapiens OX=9606 GN=S100A8 PE=1 SV=1 4.53 2316 - 2.53E+06 - - - -0.0661 - 1.009 0.027 - 152.4 1 2 0 -0.0001 7 0 0 0 6.43E+07 0.00E+00 - - - -0.7312 0.9998 221125_WJC_METTL3_EV_vs_WT_F03.10815.10815.2 0.00353 20-Nov K.VPDESEVVVER.D "sp|Q08188|TGM3_HUMAN,tr|A0A494C0J7|A0A494C0J7_HUMAN" 2 1256.6248 234.15 27529 10815 2 1256.624606 629.3197 Protein-glutamine gamma-glutamyltransferase E OS=Homo sapiens OX=9606 GN=TGM3 PE=1 SV=4 4 2316.1 - 799154 - - - -0.191 - 2.054 0.422 - 295.2 1 2 0 -0.0002 11 0 0 0 1.16E+08 4.96E+05 - - - 4.105 0.9353 221125_WJC_METTL3_EV_vs_WT_F03.10818.10818.2 0.12 12-Jul K.TQISLVR[166.11].M "sp|P30876|RPB2_HUMAN,tr|C9J4M6|C9J4M6_HUMAN,tr|C9J2Y9|C9J2Y9_HUMAN" 3 825.4948 0.69 27530 10818 2 825.492517 413.7547 DNA-directed RNA polymerase II subunit RPB2 OS=Homo sapiens OX=9606 GN=POLR2B PE=1 SV=1 9.41 2316.5 - 1.99E+06 - - - -2.7317 - 1.391 0.017 - 216.2 1 2 0 -0.0023 7 0 0 0 4.35E+07 6.28E+07 - - - 0.2115 0.973 221125_WJC_METTL3_EV_vs_WT_F03.10820.10820.2 0.000197 14-Oct R.VDQIIMAK[136.11].P "sp|P50990|TCPQ_HUMAN,tr|H7C2U0|H7C2U0_HUMAN" 2 924.5194 1.65 27531 10820 2 924.51669 463.267 T-complex protein 1 subunit theta OS=Homo sapiens OX=9606 GN=CCT8 PE=1 SV=4 5.81 2316.7 - 4.65E+06 - - - -2.9194 - 2.204 0.49 - 302.3 1 1 0 -0.0027 8 0 0 0 2.93E+08 1.78E+08 - - - 5.0427 0.95 221125_WJC_METTL3_EV_vs_WT_F03.10821.10821.2 0.162 14-Aug K.SSGPSESK[136.11].E sp|P31629|ZEP2_HUMAN 1 785.3647 0.04 27532 10821 2 785.367278 393.6896 Transcription factor HIVEP2 OS=Homo sapiens OX=9606 GN=HIVEP2 PE=1 SV=2 5.72 2316.8 - 1.10E+06 - - - 3.3309 - 1.179 0.157 - 186.6 1 2 0 0.0026 8 0 0 0 1.21E+06 2.91E+07 - - - 0.6964 0.9409 221125_WJC_METTL3_EV_vs_WT_F03.10824.10824.2 4.4 16-Jun R.YSGELSGIR.A sp|Q9NQZ2|SAS10_HUMAN 1 980.4927 0.55 27533 10824 2 980.493617 491.2536 Something about silencing protein 10 OS=Homo sapiens OX=9606 GN=UTP3 PE=1 SV=1 6 2317.2 - 1.60E+06 - - - 0.925 - 1.098 0.091 - 70.5 7 2 0 0.0009 9 0 0 0 3.70E+07 6.67E+07 - - - -0.3942 0.9889 221125_WJC_METTL3_EV_vs_WT_F03.10825.10825.2 0.00423 18-Oct R.DLDNAGELGR[166.11].S "sp|O95602|RPA1_HUMAN,tr|B9ZVN9|B9ZVN9_HUMAN" 2 1068.5075 0.99 27534 10825 2 1068.512237 535.261 DNA-directed RNA polymerase I subunit RPA1 OS=Homo sapiens OX=9606 GN=POLR1A PE=1 SV=2 4.03 2317.4 - 648873 - - - 4.4127 - 1.59 0.293 - 330.2 1 2 0 0.0047 10 0 0 0 1.59E+07 1.60E+07 - - - 2.498 0.9993 221125_WJC_METTL3_EV_vs_WT_F03.10826.10826.2 0.0156 16-Oct R.LADINYEGR[166.11].L "sp|P52948|NUP98_HUMAN,tr|A0A3B3ITD8|A0A3B3ITD8_HUMAN" 2 1059.5224 1.85 27535 10826 2 1059.521652 530.7685 Nuclear pore complex protein Nup98-Nup96 OS=Homo sapiens OX=9606 GN=NUP98 PE=1 SV=4 4.37 2317.4 - 1.61E+07 - - - -0.7475 - 1.848 0.27 - 403.5 1 2 0 -0.0008 9 0 0 0 1.13E+09 6.10E+08 - - - 2.8116 0.9907 221125_WJC_METTL3_EV_vs_WT_F03.10828.10828.2 0.253 14-Jul R.GMTVEGLK[136.11].Q "sp|P07814|SYEP_HUMAN,tr|V9GYZ6|V9GYZ6_HUMAN" 2 841.4459 0.72 27537 10828 2 841.443418 421.7302 Bifunctional glutamate\proline--tRNA ligase OS=Homo sapiens OX=9606 GN=EPRS1 PE=1 SV=5 6 2317.6 - 880403 - - - -2.9366 - 1.356 0.239 - 158.8 1 2 0 -0.0025 8 0 0 0 1.95E+07 2.72E+07 - - - 1.724 0.9982 221125_WJC_METTL3_EV_vs_WT_F03.10833.10833.2 0.0798 12-Jul R.VDPVNFK.L "sp|P69905|HBA_HUMAN,sp|P02008|HBAZ_HUMAN,tr|G3V1N2|G3V1N2_HUMAN,tr|A0A2R8Y7C0|A0A2R8Y7C0_HUMAN" 4 817.4334 48.99 27539 10833 2 817.431682 409.724 Hemoglobin subunit alpha OS=Homo sapiens OX=9606 GN=HBA1 PE=1 SV=2 5.81 2318.3 - 1.83E+06 - - - -2.1066 - 1.393 0.343 - 154.9 1 2 0 -0.0017 7 0 0 0 5.81E+07 1.19E+06 - - - 2.6241 0.9954 221125_WJC_METTL3_EV_vs_WT_F03.10838.10838.2 0.328 12-May K.FNTPALK[136.11].K "sp|P54577|SYYC_HUMAN,tr|A0A6Q8PFX2|A0A6Q8PFX2_HUMAN" 2 797.4527 0.88 27542 10838 2 797.452269 399.7336 "Tyrosine--tRNA ligase, cytoplasmic OS=Homo sapiens OX=9606 GN=YARS1 PE=1 SV=4" 8.75 2318.8 - 516418 - - - -0.5267 - 1.353 0.235 - 62.2 17 2 0 -0.0004 7 0 0 0 2.04E+07 2.30E+07 - - - 1.1849 0.9986 221125_WJC_METTL3_EV_vs_WT_F03.10840.10840.2 0.0129 18-Jul K.LFGQETPEQR[166.11].E sp|O95219|SNX4_HUMAN 1 1213.5967 1.27 27544 10840 2 1213.594342 607.8056 Sorting nexin-4 OS=Homo sapiens OX=9606 GN=SNX4 PE=1 SV=1 4.53 2319.1 - 326726 - - - -1.9191 - 1.462 0.358 - 130.1 1 2 0 -0.0023 10 0 0 0 4.61E+06 3.62E+06 - - - 2.7446 0.9945 221125_WJC_METTL3_EV_vs_WT_F03.10843.10843.2 0.8 12-Jun K.EDLTEIR[166.11].D "sp|Q8NHW5|RLA0L_HUMAN,sp|P05388|RLA0_HUMAN,tr|G3V210|G3V210_HUMAN,tr|F8VU65|F8VU65_HUMAN,tr|F8VWV4|F8VWV4_HUMAN,tr|F8VWS0|F8VWS0_HUMAN,tr|F8VS58|F8VS58_HUMAN,tr|F8VW21|F8VW21_HUMAN,tr|F8VZS0|F8VZS0_HUMAN,tr|F8VRK7|F8VRK7_HUMAN,tr|F8VQY6|F8VQY6_HUMAN,tr|F8VPE8|F8VPE8_HUMAN" 12 884.4479 2.48 27545 10843 2 884.446294 443.2312 60S acidic ribosomal protein P0-like OS=Homo sapiens OX=9606 GN=RPLP0P6 PE=5 SV=1 4.14 2319.5 - 2.31E+07 - - - -1.7955 - 1.469 0.167 - 182.9 1 2 0 -0.0016 7 0 0 0 2.19E+09 8.84E+08 - - - 1.4925 0.9945 221125_WJC_METTL3_EV_vs_WT_F03.10845.10845.2 0.149 14-May K.IDNNPFAK[136.11].G "sp|Q9UL17|TBX21_HUMAN,sp|Q13207|TBX2_HUMAN,sp|O15119|TBX3_HUMAN" 3 925.4749 1.15 27547 10845 2 925.475553 463.7447 T-box transcription factor TBX21 OS=Homo sapiens OX=9606 GN=TBX21 PE=1 SV=1 5.84 2319.6 - 2.59E+06 - - - 0.7261 - 1.3 0.197 - 62.5 2 2 0 0.0007 8 0 0 0 2.98E+08 2.60E+08 - - - 1.1526 0.9995 221125_WJC_METTL3_EV_vs_WT_F03.10846.10846.2 0.000142 22-Oct K.ALSTDPAAPNLK.S sp|Q9Y490|TLN1_HUMAN 1 1196.6401 1.51 27548 10846 2 1196.637423 599.3273 Talin-1 OS=Homo sapiens OX=9606 GN=TLN1 PE=1 SV=3 5.88 2319.7 - 576601 - - - -2.2388 - 1.877 0.468 - 255.4 1 2 0 -0.0027 12 0 0 0 2.41E+07 1.60E+07 - - - 4.1536 0.9995 221125_WJC_METTL3_EV_vs_WT_F03.10847.10847.2 0.000286 22-Aug K.ALSTDPAAPNLK[136.11].S sp|Q9Y490|TLN1_HUMAN 1 1204.6543 1.51 27549 10847 2 1204.651967 603.3344 Talin-1 OS=Homo sapiens OX=9606 GN=TLN1 PE=1 SV=3 5.88 2319.9 - 514133 - - - -1.9383 - 1.772 0.463 - 174.4 1 2 0 -0.0023 12 0 0 0 2.41E+07 1.60E+07 - - - 3.9653 0.9998 221125_WJC_METTL3_EV_vs_WT_F03.10848.10848.2 0.00667 13/24 R.ATAGAYIASQTVK[136.11].K "sp|P28074|PSB5_HUMAN,tr|H0YJM8|H0YJM8_HUMAN" 2 1287.6914 0.7 27550 10848 2 1287.690656 644.853 Proteasome subunit beta type-5 OS=Homo sapiens OX=9606 GN=PSMB5 PE=1 SV=3 8.63 2320 - 392234 - - - -0.5902 - 2.105 0.397 - 554.7 1 2 0 -0.0008 13 0 0 0 4.30E+06 6.15E+06 - - - 3.8833 0.9999 221125_WJC_METTL3_EV_vs_WT_F03.10851.10851.2 0.000834 20-Nov R.GLGAIQPGVNR.C "sp|Q9UI36|DACH1_HUMAN,sp|Q96NX9|DACH2_HUMAN,tr|D6RFG7|D6RFG7_HUMAN,tr|D6REJ4|D6REJ4_HUMAN" 4 1080.604 2.05 27551 10851 2 1080.603578 541.3093 Dachshund homolog 1 OS=Homo sapiens OX=9606 GN=DACH1 PE=1 SV=4 9.75 2320.4 - 2.29E+07 - - - -0.3831 - 2.341 0.438 - 422.8 1 2 0 -0.0004 11 0 0 0 7.30E+08 3.57E+08 - - - 4.577 0.9761 221125_WJC_METTL3_EV_vs_WT_F03.10852.10852.2 1.17 14-May K.EIEANEWK.K "sp|O75410|TACC1_HUMAN,tr|E7EVI4|E7EVI4_HUMAN,tr|B4E3H6|B4E3H6_HUMAN,tr|R4GMT7|R4GMT7_HUMAN,tr|H0YAY0|H0YAY0_HUMAN,tr|H0YBT8|H0YBT8_HUMAN,tr|E7ET87|E7ET87_HUMAN" 7 1017.4767 0.9 27552 10852 2 1017.477104 509.7456 Transforming acidic coiled-coil-containing protein 1 OS=Homo sapiens OX=9606 GN=TACC1 PE=1 SV=2 4.25 2320.5 - 3.75E+06 - - - 0.3725 - 0.964 0.155 - 84 1 2 0 0.0004 8 0 0 0 6.90E+07 7.66E+07 - - - 0.0751 0.9917 221125_WJC_METTL3_EV_vs_WT_F03.10853.10853.2 0.578 14-Aug K.EIEANEWK[136.11].K "sp|O75410|TACC1_HUMAN,tr|E7EVI4|E7EVI4_HUMAN,tr|B4E3H6|B4E3H6_HUMAN,tr|R4GMT7|R4GMT7_HUMAN,tr|H0YAY0|H0YAY0_HUMAN,tr|H0YBT8|H0YBT8_HUMAN,tr|E7ET87|E7ET87_HUMAN" 7 1025.4909 1.13 27553 10853 2 1025.490726 513.7527 Transforming acidic coiled-coil-containing protein 1 OS=Homo sapiens OX=9606 GN=TACC1 PE=1 SV=2 4.25 2320.5 - 3.42E+06 - - - -0.1941 - 1.205 0.154 - 193.4 1 2 0 -0.0002 8 0 0 0 8.70E+07 7.73E+07 - - - 0.7408 0.9999 221125_WJC_METTL3_EV_vs_WT_F03.10855.10855.2 0.00281 22-Nov R.TLIQNC[160.03]GASTIR[166.11].L "sp|P49368|TCPG_HUMAN,tr|B4DUR8|B4DUR8_HUMAN" 2 1342.6903 0.17 27555 10855 2 1342.68942 672.3524 T-complex protein 1 subunit gamma OS=Homo sapiens OX=9606 GN=CCT3 PE=1 SV=4 7.91 2320.7 - 810165 - - - -0.6211 - 2.111 0.515 - 300.5 1 2 0 -0.0008 12 0 0 0 2.20E+06 1.26E+07 - - - 4.8104 0.9971 221125_WJC_METTL3_EV_vs_WT_F03.10856.10856.2 0.0247 16-Jun R.EYQELMNTK.L "sp|P13647|K2C5_HUMAN,tr|H0YI76|H0YI76_HUMAN" 2 1154.5278 0.71 27556 10856 2 1154.529907 578.2712 "Keratin, type II cytoskeletal 5 OS=Homo sapiens OX=9606 GN=KRT5 PE=1 SV=3" 4.53 2320.8 - 719104 - - - 1.8466 - 1.211 0.337 - 116.8 1 2 0 0.0021 9 0 0 0 1.02E+07 1.44E+07 - - - 2.0833 0.9993 221125_WJC_METTL3_EV_vs_WT_F03.10858.10858.2 0.0464 18-Sep R.GVPQQIEVAR[166.11].Q sp|Q96I24|FUBP3_HUMAN 1 1105.6119 1.99 27557 10858 2 1105.612645 553.8132 Far upstream element-binding protein 3 OS=Homo sapiens OX=9606 GN=FUBP3 PE=1 SV=2 6 2321.1 - 5.18E+06 - - - 0.6494 - 1.7 0.321 - 386.5 1 2 0 0.0007 10 0 0 0 1.68E+09 8.46E+08 - - - 2.8928 0.9995 221125_WJC_METTL3_EV_vs_WT_F03.10860.10860.2 0.00392 14-Jul K.SSETLTFK[136.11].R "sp|Q9NPF5|DMAP1_HUMAN,tr|Q5TG39|Q5TG39_HUMAN,tr|Q5TG38|Q5TG38_HUMAN,tr|Q5TG40|Q5TG40_HUMAN,tr|Q5TG36|Q5TG36_HUMAN,tr|Q5TG37|Q5TG37_HUMAN" 6 919.4742 1.51 27558 10860 2 919.473696 460.7444 DNA methyltransferase 1-associated protein 1 OS=Homo sapiens OX=9606 GN=DMAP1 PE=1 SV=1 5.72 2321.3 - 2.47E+06 - - - -0.5623 - 1.583 0.353 - 138.3 1 2 0 -0.0005 8 0 0 0 1.34E+08 8.87E+07 - - - 3.0334 0.9683 221125_WJC_METTL3_EV_vs_WT_F03.10862.10862.2 0.552 12-May K.YTVPGYR.N sp|Q9BVP2|GNL3_HUMAN 1 854.4287 0.83 27560 10862 2 854.42862 428.2216 Guanine nucleotide-binding protein-like 3 OS=Homo sapiens OX=9606 GN=GNL3 PE=1 SV=2 8.59 2321.4 - 1.65E+06 - - - -0.0386 - 1.091 0.091 - 112.5 2 2 0 0 7 0 0 0 9.04E+07 1.09E+08 - - - -0.1454 0.9831 221125_WJC_METTL3_EV_vs_WT_F03.10863.10863.2 0.253 16-May K.LR[166.11]PIAVIK[136.11]G.- sp|Q9Y3I0|RTCB_HUMAN 1 983.6611 1.24 27561 10863 2 983.660712 492.8378 RNA-splicing ligase RtcB homolog OS=Homo sapiens OX=9606 GN=RTCB PE=1 SV=1 11 2321.5 - 1.52E+06 - - - -0.3497 - 1.193 0.14 - 70.1 5 2 0 -0.0003 9 0 0 0 3.56E+07 2.88E+07 - - - 0.2732 0.975 221125_WJC_METTL3_EV_vs_WT_F03.10867.10867.2 3.46 12-Jul K.SFSEFGK[136.11].L "sp|O43390|HNRPR_HUMAN,tr|B4DT28|B4DT28_HUMAN,tr|A0A6Q8PHG0|A0A6Q8PHG0_HUMAN,tr|A0A6Q8PH31|A0A6Q8PH31_HUMAN,tr|A0A6Q8PH35|A0A6Q8PH35_HUMAN" 5 808.3847 1.33 27563 10867 2 808.38522 405.1996 Heterogeneous nuclear ribonucleoprotein R OS=Homo sapiens OX=9606 GN=HNRNPR PE=1 SV=1 5.72 2322 - 2.87E+06 - - - 0.6816 - 1.017 0.137 - 186.1 1 2 0 0.0006 7 0 0 0 3.77E+08 2.83E+08 - - - 0.1061 0.9961 221125_WJC_METTL3_EV_vs_WT_F03.10868.10868.2 0.181 12-Jul R.DLDELSR.Y "sp|P43243|MATR3_HUMAN,tr|A8MXP9|A8MXP9_HUMAN,tr|D6R991|D6R991_HUMAN,tr|A0A0R4J2E8|A0A0R4J2E8_HUMAN,tr|D6REM6|D6REM6_HUMAN" 5 846.4083 1.39 27564 10868 2 846.409982 424.2114 Matrin-3 OS=Homo sapiens OX=9606 GN=MATR3 PE=1 SV=2 4.03 2322.1 - 2.76E+06 - - - 1.9742 - 1.314 0.272 - 186.3 1 2 0 0.0017 7 0 0 0 6.12E+09 4.39E+09 - - - 1.9147 0.998 221125_WJC_METTL3_EV_vs_WT_F03.10869.10869.2 0.264 14-Aug K.AGGSFDLR.R "sp|O43760|SNG2_HUMAN,tr|K7ENG9|K7ENG9_HUMAN,tr|K7ELS8|K7ELS8_HUMAN,tr|K7ELD9|K7ELD9_HUMAN" 4 821.4032 0.88 27565 10869 2 821.402938 411.7089 Synaptogyrin-2 OS=Homo sapiens OX=9606 GN=SYNGR2 PE=1 SV=1 5.88 2322.2 - 1.50E+06 - - - -0.2776 - 1.762 0.143 - 331.7 1 2 0 -0.0002 8 0 0 0 3.06E+07 3.48E+07 - - - 1.8055 0.9992 221125_WJC_METTL3_EV_vs_WT_F03.10875.10875.2 0.0248 12-Jul K.SFSEFGK.L "sp|O43390|HNRPR_HUMAN,tr|B4DT28|B4DT28_HUMAN,tr|A0A6Q8PHG0|A0A6Q8PHG0_HUMAN,tr|A0A6Q8PH31|A0A6Q8PH31_HUMAN,tr|A0A6Q8PH35|A0A6Q8PH35_HUMAN" 5 800.3705 1.28 27569 10875 2 800.370024 401.1925 Heterogeneous nuclear ribonucleoprotein R OS=Homo sapiens OX=9606 GN=HNRNPR PE=1 SV=1 5.72 2322.9 - 4.74E+06 - - - -0.556 - 1.397 0.332 - 178.1 1 2 0 -0.0004 7 0 0 0 3.79E+08 2.96E+08 - - - 2.5523 0.9651 221125_WJC_METTL3_EV_vs_WT_F03.10876.10876.2 1.21 12-Jul R.ETELELR.E "sp|Q14203|DCTN1_HUMAN,tr|A0A804CDA6|A0A804CDA6_HUMAN,tr|E7EX90|E7EX90_HUMAN,tr|A0A7P0Z4C3|A0A7P0Z4C3_HUMAN,tr|Q6AWB1|Q6AWB1_HUMAN" 5 888.4553 4.78 27570 10876 2 888.457559 445.2349 Dynactin subunit 1 OS=Homo sapiens OX=9606 GN=DCTN1 PE=1 SV=3 4.25 2322.9 - 3.58E+06 - - - 2.5854 - 1.452 0.05 - 288.5 1 2 0 0.0023 7 0 0 0 7.05E+08 1.48E+08 - - - 0.5913 0.9988 221125_WJC_METTL3_EV_vs_WT_F03.10877.10877.2 0.0459 16-Jul K.AMYSAELEK.Q "sp|Q15643|TRIPB_HUMAN,tr|H0YJI2|H0YJI2_HUMAN,tr|H0YJ97|H0YJ97_HUMAN" 3 1040.4848 0.71 27571 10877 2 1040.48543 521.2497 Thyroid receptor-interacting protein 11 OS=Homo sapiens OX=9606 GN=TRIP11 PE=1 SV=3 4.53 2323 - 2.67E+06 - - - 0.5603 - 1.261 0.349 - 143.6 1 2 0 0.0006 9 0 0 0 1.07E+08 1.51E+08 - - - 2.2894 0.9998 221125_WJC_METTL3_EV_vs_WT_F03.10884.10884.3 0.000199 Dec-36 R.IVGWYHTGPK[136.11].L "sp|P51665|PSMD7_HUMAN,tr|H3BNT7|H3BNT7_HUMAN,tr|H3BTM8|H3BTM8_HUMAN" 3 1164.6171 0.61 27576 10884 3 1164.615904 389.213 26S proteasome non-ATPase regulatory subunit 7 OS=Homo sapiens OX=9606 GN=PSMD7 PE=1 SV=2 8.6 2323.8 - 1.53E+06 - - - -1.0518 - 2.121 0.343 - 179.8 1 2 0 -0.0012 10 0 0 0 3.37E+07 5.56E+07 - - - 4.5596 0.9757 221125_WJC_METTL3_EV_vs_WT_F03.10885.10885.2 0.14 16-Sep K.NPVMELNEK.R "sp|Q12906|ILF3_HUMAN,sp|Q96SI9|STRBP_HUMAN" 2 1072.5223 0.97 27577 10885 2 1072.527063 537.2684 Interleukin enhancer-binding factor 3 OS=Homo sapiens OX=9606 GN=ILF3 PE=1 SV=3 4.53 2323.9 - 1.67E+06 - - - 4.4456 - 1.598 0.196 - 349.4 1 2 0 0.0048 9 0 0 0 3.98E+08 4.08E+08 - - - 1.8433 0.9968 221125_WJC_METTL3_EV_vs_WT_F03.10886.10886.2 0.0131 16-Jun R.EATADDLIK[136.11].V "sp|Q16531|DDB1_HUMAN,tr|A0A7P0TAK7|A0A7P0TAK7_HUMAN,tr|A0A7P0T870|A0A7P0T870_HUMAN,tr|A0A7P0TB30|A0A7P0TB30_HUMAN,tr|A0A7P0Z3Z5|A0A7P0Z3Z5_HUMAN,tr|A0A7P0Z4B9|A0A7P0Z4B9_HUMAN,tr|A0A7P0T965|A0A7P0T965_HUMAN" 7 982.5062 0.98 27578 10886 2 982.505989 492.2604 DNA damage-binding protein 1 OS=Homo sapiens OX=9606 GN=DDB1 PE=1 SV=1 4.03 2323.9 - 1.31E+06 - - - -0.2565 - 1.223 0.244 - 98 1 2 0 -0.0003 9 0 0 0 1.45E+08 1.48E+08 - - - 1.4255 0.9941 221125_WJC_METTL3_EV_vs_WT_F03.10887.10887.2 0.023 16-Jun R.EATADDLIK.V "sp|Q16531|DDB1_HUMAN,tr|A0A7P0TAK7|A0A7P0TAK7_HUMAN,tr|A0A7P0T870|A0A7P0T870_HUMAN,tr|A0A7P0TB30|A0A7P0TB30_HUMAN,tr|A0A7P0Z3Z5|A0A7P0Z3Z5_HUMAN,tr|A0A7P0Z4B9|A0A7P0Z4B9_HUMAN,tr|A0A7P0T965|A0A7P0T965_HUMAN" 7 974.492 0.87 27579 10887 2 974.494424 488.2533 DNA damage-binding protein 1 OS=Homo sapiens OX=9606 GN=DDB1 PE=1 SV=1 4.03 2324 - 919462 - - - 2.4454 - 1.325 0.267 - 79.6 1 2 0 0.0024 9 0 0 0 1.26E+08 1.45E+08 - - - 1.8265 0.9886 221125_WJC_METTL3_EV_vs_WT_F03.10888.10888.3 0.166 Dec-36 R.IVGWYHTGPK.L "sp|P51665|PSMD7_HUMAN,tr|H3BNT7|H3BNT7_HUMAN,tr|H3BTM8|H3BTM8_HUMAN" 3 1156.6029 0.4 27580 10888 3 1156.601642 386.5416 26S proteasome non-ATPase regulatory subunit 7 OS=Homo sapiens OX=9606 GN=PSMD7 PE=1 SV=2 8.6 2324.1 - 841793 - - - -1.1127 - 2.039 0.102 - 130 1 2 0 -0.0013 10 0 0 0 3.48E+07 8.71E+07 - - - 1.7575 0.9999 221125_WJC_METTL3_EV_vs_WT_F03.10889.10889.2 1.40E-08 26-Nov K.MMGGAGPGSSLEAR.S "sp|O95785|WIZ_HUMAN,tr|A0A669KBG4|A0A669KBG4_HUMAN,tr|A0A2R8YFV2|A0A2R8YFV2_HUMAN,tr|A0A669KAV7|A0A669KAV7_HUMAN,tr|M0QXA7|M0QXA7_HUMAN,tr|A0A669KBH9|A0A669KBH9_HUMAN,tr|B9EGQ5|B9EGQ5_HUMAN" 7 1319.5962 1.38 27581 10889 2 1319.596379 660.8054 Protein Wiz OS=Homo sapiens OX=9606 GN=WIZ PE=1 SV=2 5.75 2324.2 - 564797 - - - 0.1319 - 2.224 0.623 - 275.9 1 2 0 0.0002 14 0 0 0 1.68E+07 1.21E+07 - - - 5.6482 0.9982 221125_WJC_METTL3_EV_vs_WT_F03.10890.10890.2 0.000292 16-Aug K.NIPVYEC[160.03]ER.S "sp|O75569|PRKRA_HUMAN,tr|A0A7I2V5C2|A0A7I2V5C2_HUMAN,tr|A0A7I2V5H3|A0A7I2V5H3_HUMAN,tr|A0A7I2V2P4|A0A7I2V2P4_HUMAN,tr|F8WEG8|F8WEG8_HUMAN,tr|G5E9Q4|G5E9Q4_HUMAN,tr|A0A7I2YQ87|A0A7I2YQ87_HUMAN,tr|C9JMM3|C9JMM3_HUMAN,tr|A0A7I2V3L6|A0A7I2V3L6_HUMAN" 9 1178.539 0.11 27582 10890 2 1178.535583 590.2768 Interferon-inducible double-stranded RNA-dependent protein kinase activator A OS=Homo sapiens OX=9606 GN=PRKRA PE=1 SV=1 4.53 2324.4 - 438476 - - - -2.9061 - 1.33 0.449 - 244.4 1 2 0 -0.0034 9 0 0 0 3.60E+07 3.30E+08 - - - 3.1813 0.9995 221125_WJC_METTL3_EV_vs_WT_F03.10897.10897.2 0.00485 18-Sep K.LEQGTSALIR.Q "sp|Q8IWC1|MA7D3_HUMAN,tr|A0A0A0MRP0|A0A0A0MRP0_HUMAN" 2 1086.6033 0.17 27587 10897 2 1086.604225 544.3089 MAP7 domain-containing protein 3 OS=Homo sapiens OX=9606 GN=MAP7D3 PE=1 SV=2 6 2325.2 - 2.78E+06 - - - 0.8301 - 1.674 0.377 - 261.6 1 2 0 0.0009 10 0 0 0 7.32E+07 4.38E+08 - - - 3.2634 0.9995 221125_WJC_METTL3_EV_vs_WT_F03.10899.10899.2 0.144 16-Aug R.ISAISVAER[166.11].V "sp|Q6P158|DHX57_HUMAN,sp|Q9H2U1|DHX36_HUMAN,tr|E7EWK3|E7EWK3_HUMAN" 3 954.5374 0.63 27589 10899 2 954.536483 478.276 Putative ATP-dependent RNA helicase DHX57 OS=Homo sapiens OX=9606 GN=DHX57 PE=1 SV=2 6 2325.4 - 1.04E+06 - - - -0.924 - 1.904 0.3 - 158.5 1 2 0 -0.0009 9 0 0 0 1.20E+08 1.91E+08 - - - 3.1195 0.9999 221125_WJC_METTL3_EV_vs_WT_F03.10900.10900.2 6.11E-09 16/26 K.MMGGAGPGSSLEAR[166.11].S "sp|O95785|WIZ_HUMAN,tr|A0A669KBG4|A0A669KBG4_HUMAN,tr|A0A2R8YFV2|A0A2R8YFV2_HUMAN,tr|A0A669KAV7|A0A669KAV7_HUMAN,tr|M0QXA7|M0QXA7_HUMAN,tr|A0A669KBH9|A0A669KBH9_HUMAN,tr|B9EGQ5|B9EGQ5_HUMAN" 7 1329.6045 1.38 27590 10900 2 1329.604029 665.8095 Protein Wiz OS=Homo sapiens OX=9606 GN=WIZ PE=1 SV=2 5.75 2325.5 - 380808 - - - -0.3354 - 2.433 0.594 - 549.3 1 2 0 -0.0004 14 0 0 0 1.68E+07 1.21E+07 - - - 5.6594 0.9995 221125_WJC_METTL3_EV_vs_WT_F03.10903.10903.2 0.0261 16-Aug R.ISAISVAER.V "sp|Q6P158|DHX57_HUMAN,sp|Q9H2U1|DHX36_HUMAN,tr|E7EWK3|E7EWK3_HUMAN" 3 944.5291 0.63 27591 10903 2 944.530103 473.2718 Putative ATP-dependent RNA helicase DHX57 OS=Homo sapiens OX=9606 GN=DHX57 PE=1 SV=2 6 2325.9 - 1.50E+06 - - - 1.0672 - 1.774 0.364 - 184.4 1 2 0 0.001 9 0 0 0 1.20E+08 1.89E+08 - - - 3.3876 0.9997 221125_WJC_METTL3_EV_vs_WT_F03.10905.10905.2 0.000392 16-Sep K.NPVMELNEK[136.11].R "sp|Q12906|ILF3_HUMAN,sp|Q96SI9|STRBP_HUMAN" 2 1080.5365 1.17 27593 10905 2 1080.537588 541.2755 Interleukin enhancer-binding factor 3 OS=Homo sapiens OX=9606 GN=ILF3 PE=1 SV=3 4.53 2326.1 - 4.24E+06 - - - 1.0115 - 1.974 0.42 - 527.9 1 2 0 0.0011 9 0 0 0 3.68E+08 3.13E+08 - - - 4.1102 0.9993 221125_WJC_METTL3_EV_vs_WT_F03.10906.10906.2 0.0078 16-Jul K.DNGVVPVVK[136.11].E "sp|Q9P2J5|SYLC_HUMAN,tr|A0A6I8PIV1|A0A6I8PIV1_HUMAN,tr|A0A6I8PRS0|A0A6I8PRS0_HUMAN,tr|A0A6I8PLB8|A0A6I8PLB8_HUMAN,tr|A0A6I8PIP7|A0A6I8PIP7_HUMAN,tr|A0A6I8PIT3|A0A6I8PIT3_HUMAN,tr|A0A6I8PTV8|A0A6I8PTV8_HUMAN,tr|A0A6I8PRU9|A0A6I8PRU9_HUMAN,tr|A0A6I8PS05|A0A6I8PS05_HUMAN,tr|B4DER1|B4DER1_HUMAN,tr|A0A6I8PL42|A0A6I8PL42_HUMAN" 11 933.5375 1.94 27594 10906 2 933.537387 467.776 "Leucine--tRNA ligase, cytoplasmic OS=Homo sapiens OX=9606 GN=LARS1 PE=1 SV=2" 5.84 2326.1 - 1.66E+06 - - - -0.1018 - 1.449 0.356 - 191.5 1 2 0 -0.0001 9 0 0 0 1.61E+08 8.31E+07 - - - 2.7433 0.9997 221125_WJC_METTL3_EV_vs_WT_F03.10913.10913.2 0.0185 16-Sep K.AENQVLAMR[166.11].K "sp|P51572|BAP31_HUMAN,tr|A0A2R8Y5M6|A0A2R8Y5M6_HUMAN" 2 1040.5312 0.94 27599 10913 2 1040.531211 521.2729 B-cell receptor-associated protein 31 OS=Homo sapiens OX=9606 GN=BCAP31 PE=1 SV=3 6.05 2326.9 - 4.86E+06 - - - -0.0221 - 1.858 0.375 - 366.1 1 2 0 0 9 0 0 0 2.15E+08 2.29E+08 - - - 3.603 0.9995 221125_WJC_METTL3_EV_vs_WT_F03.10914.10914.2 4.38E-08 20-Dec R.YATALYSAASK[136.11].Q "sp|P48047|ATPO_HUMAN,tr|H7C086|H7C086_HUMAN,tr|H7C0C1|H7C0C1_HUMAN,tr|A0A494C0K9|A0A494C0K9_HUMAN" 4 1152.5906 1.01 27600 10914 2 1152.586825 577.3026 "ATP synthase subunit O, mitochondrial OS=Homo sapiens OX=9606 GN=ATP5PO PE=1 SV=1" 8.5 2327 - 513448 - - - -3.3099 - 2.384 0.538 - 413.6 1 2 0 -0.0038 11 0 0 0 4.57E+08 4.53E+08 - - - 5.3637 0.987 221125_WJC_METTL3_EV_vs_WT_F03.10915.10915.2 1.05 12-Aug R.QLDAEIK.A "sp|A4D1P6|WDR91_HUMAN,tr|A0A804HI90|A0A804HI90_HUMAN,tr|A0A804HKV2|A0A804HKV2_HUMAN,tr|A0A804HJP3|A0A804HJP3_HUMAN" 4 815.4389 11.3 27601 10915 2 815.439176 408.7267 WD repeat-containing protein 91 OS=Homo sapiens OX=9606 GN=WDR91 PE=1 SV=2 4.37 2327.1 - 1.01E+06 - - - 0.3593 - 1.569 0.001 - 231 1 2 0 0.0003 7 0 0 0 3.73E+07 3.30E+06 - - - 0.4755 0.9979 221125_WJC_METTL3_EV_vs_WT_F03.10916.10916.2 0.000497 18-Oct R.FITDNTVEER.L sp|O60264|SMCA5_HUMAN 1 1222.583 0.95 27602 10916 2 1222.586768 612.2988 SWI\SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A member 5 OS=Homo sapiens OX=9606 GN=SMARCA5 PE=1 SV=1 4.14 2327.3 - 514530 - - - 3.0975 - 1.493 0.411 - 163.7 1 2 0 0.0038 10 0 0 0 9.32E+07 9.80E+07 - - - 3.1942 0.994 221125_WJC_METTL3_EV_vs_WT_F03.10917.10917.2 0.00048 22-Sep K.FASC[160.03]VDASGGLK.C "sp|Q8IXT5|RB12B_HUMAN,tr|B9ZVT1|B9ZVT1_HUMAN" 2 1210.5652 1.67 27603 10917 2 1210.558167 606.2899 RNA-binding protein 12B OS=Homo sapiens OX=9606 GN=RBM12B PE=1 SV=2 5.83 2327.4 - 495926 - - - -5.8287 - 1.751 0.508 - 181.7 1 2 0 -0.0071 12 0 0 0 1.52E+07 9.12E+06 - - - 4.2648 0.9996 221125_WJC_METTL3_EV_vs_WT_F03.10924.10924.2 2.77E-05 20-Sep R.GGVEEGPTVLR.K "sp|P05089|ARGI1_HUMAN,tr|A0A5F9ZH78|A0A5F9ZH78_HUMAN" 2 1112.5826 1384.64 27608 10924 2 1112.582828 557.2986 Arginase-1 OS=Homo sapiens OX=9606 GN=ARG1 PE=1 SV=2 4.53 2328.2 - 5.63E+06 - - - 0.2157 - 2.078 0.325 - 387.8 1 2 0 0.0002 11 0 0 0 3.95E+08 2.85E+05 - - - 3.42 0.9993 221125_WJC_METTL3_EV_vs_WT_F03.10930.10930.2 0.00868 18-Oct R.IVGWYHTGPK[136.11].L "sp|P51665|PSMD7_HUMAN,tr|H3BNT7|H3BNT7_HUMAN,tr|H3BTM8|H3BTM8_HUMAN" 3 1164.6171 2.11 27612 10930 2 1164.616249 583.3158 26S proteasome non-ATPase regulatory subunit 7 OS=Homo sapiens OX=9606 GN=PSMD7 PE=1 SV=2 8.6 2328.9 - 261497 - - - -0.7556 - 1.616 0.332 - 209.9 1 2 0 -0.0009 10 0 0 0 1.58E+07 7.50E+06 - - - 2.8326 0.9998 221125_WJC_METTL3_EV_vs_WT_F03.10931.10931.2 0.000273 16-Sep K.AENQVLAMR.K "sp|P51572|BAP31_HUMAN,tr|A0A2R8Y5M6|A0A2R8Y5M6_HUMAN" 2 1030.523 0.93 27613 10931 2 1030.522981 516.2688 B-cell receptor-associated protein 31 OS=Homo sapiens OX=9606 GN=BCAP31 PE=1 SV=3 6.05 2328.9 - 7.01E+06 - - - 0.0165 - 1.728 0.449 - 211.9 1 2 0 0 9 0 0 0 2.15E+08 2.30E+08 - - - 3.9397 0.9999 221125_WJC_METTL3_EV_vs_WT_F03.10934.10934.2 0.000212 16-Aug K.VPVDEFDGK[136.11].V "sp|Q92499|DDX1_HUMAN,tr|A0A7I2V2M5|A0A7I2V2M5_HUMAN,tr|A0A087X2G1|A0A087X2G1_HUMAN,tr|A0A7I2V430|A0A7I2V430_HUMAN,tr|A0A7I2V4F0|A0A7I2V4F0_HUMAN,tr|A0A087WZ71|A0A087WZ71_HUMAN,tr|A0A7I2YQ77|A0A7I2YQ77_HUMAN" 7 1012.4957 1.83 27614 10934 2 1012.49559 507.2551 ATP-dependent RNA helicase DDX1 OS=Homo sapiens OX=9606 GN=DDX1 PE=1 SV=2 4.03 2329.3 - 3.51E+06 - - - -0.0849 - 1.847 0.513 - 250.8 1 2 0 -0.0001 9 0 0 0 2.29E+08 1.25E+08 - - - 4.6051 1 221125_WJC_METTL3_EV_vs_WT_F03.10935.10935.2 5.47E-06 20-Nov R.YATALYSAASK.Q "sp|P48047|ATPO_HUMAN,tr|H7C086|H7C086_HUMAN,tr|H7C0C1|H7C0C1_HUMAN,tr|A0A494C0K9|A0A494C0K9_HUMAN" 4 1144.5764 1.01 27615 10935 2 1144.576593 573.2955 "ATP synthase subunit O, mitochondrial OS=Homo sapiens OX=9606 GN=ATP5PO PE=1 SV=1" 8.5 2329.4 - 2.62E+06 - - - 0.1337 - 2.211 0.621 - 360.1 1 2 0 0.0002 11 0 0 0 4.57E+08 4.53E+08 - - - 5.7741 0.9988 221125_WJC_METTL3_EV_vs_WT_F03.10936.10936.2 0.018 16-Aug R.VYAEVNSLR[166.11].S "sp|P19784|CSK22_HUMAN,tr|H3BNI9|H3BNI9_HUMAN" 2 1059.5588 1.85 27616 10936 2 1059.559841 530.7867 Casein kinase II subunit alpha' OS=Homo sapiens OX=9606 GN=CSNK2A2 PE=1 SV=1 5.97 2329.4 - 1.06E+06 - - - 0.9551 - 1.385 0.331 - 175.7 1 2 0 0.001 9 0 0 0 1.08E+08 5.87E+07 - - - 2.4277 0.9836 221125_WJC_METTL3_EV_vs_WT_F03.10937.10937.2 0.00365 18-Oct L.LYSSVENIQR.V sp|P14923|PLAK_HUMAN 1 1207.6197 14.97 27617 10937 2 1207.618755 604.8171 Junction plakoglobin OS=Homo sapiens OX=9606 GN=JUP PE=1 SV=3 6 2329.6 - 609551 - - - -0.7834 - 1.855 0.409 - 346.2 1 1 0 -0.0009 10 0 0 0 3.31E+07 2.21E+06 - - - 3.7863 0.9997 221125_WJC_METTL3_EV_vs_WT_F03.10942.10942.2 0.000459 16-Aug K.VPVDEFDGK.V "sp|Q92499|DDX1_HUMAN,tr|A0A7I2V2M5|A0A7I2V2M5_HUMAN,tr|A0A087X2G1|A0A087X2G1_HUMAN,tr|A0A7I2V430|A0A7I2V430_HUMAN,tr|A0A7I2V4F0|A0A7I2V4F0_HUMAN,tr|A0A087WZ71|A0A087WZ71_HUMAN,tr|A0A7I2YQ77|A0A7I2YQ77_HUMAN" 7 1004.4815 1.63 27619 10942 2 1004.48074 503.248 ATP-dependent RNA helicase DDX1 OS=Homo sapiens OX=9606 GN=DDX1 PE=1 SV=2 4.03 2330.2 - 5.05E+06 - - - -0.7327 - 1.67 0.435 - 152.5 1 2 0 -0.0007 9 0 0 0 2.04E+08 1.25E+08 - - - 3.7373 0.9998 221125_WJC_METTL3_EV_vs_WT_F03.10943.10943.2 0.000655 18-Oct K.ATAVVDGAFK.E "sp|P32119|PRDX2_HUMAN,tr|A6NIW5|A6NIW5_HUMAN" 2 977.5182 0.85 27620 10943 2 977.518067 489.7664 Peroxiredoxin-2 OS=Homo sapiens OX=9606 GN=PRDX2 PE=1 SV=5 5.88 2330.2 - 6.19E+06 - - - -0.132 - 2.072 0.392 - 468.5 1 2 0 -0.0001 10 0 0 0 4.76E+08 5.62E+08 - - - 3.9698 0.9929 221125_WJC_METTL3_EV_vs_WT_F03.10947.10947.2 0.708 12-Jul K.TWQANLR[166.11].L "sp|P06730|IF4E_HUMAN,tr|H0Y8J7|H0Y8J7_HUMAN,tr|D6RBW1|D6RBW1_HUMAN" 3 897.4696 0.01 27622 10947 2 897.46843 449.7421 Eukaryotic translation initiation factor 4E OS=Homo sapiens OX=9606 GN=EIF4E PE=1 SV=2 9.41 2330.7 - 7.43E+06 - - - -1.326 - 1.336 0.153 - 321.2 1 2 0 -0.0012 7 0 0 0 6.06E+08 6.19E+10 - - - 1.0886 0.999 221125_WJC_METTL3_EV_vs_WT_F03.10952.10952.2 0.406 16-Aug R.VYAEVNSLR.S "sp|P19784|CSK22_HUMAN,tr|H3BNI9|H3BNI9_HUMAN" 2 1049.5506 1.04 27625 10952 2 1049.552551 525.7826 Casein kinase II subunit alpha' OS=Homo sapiens OX=9606 GN=CSNK2A2 PE=1 SV=1 5.97 2331.3 - 1.47E+06 - - - 1.898 - 1.533 0.383 - 181 1 2 0 0.002 9 0 0 0 4.92E+07 4.74E+07 - - - 3.1052 0.9998 221125_WJC_METTL3_EV_vs_WT_F03.10957.10957.2 7.71E-05 18-Oct R.GINVALANGK[136.11].T "sp|Q92520|FAM3C_HUMAN,tr|C9JMN4|C9JMN4_HUMAN,tr|C9JP35|C9JP35_HUMAN" 3 963.5593 1.45 27628 10957 2 963.558796 482.7869 Protein FAM3C OS=Homo sapiens OX=9606 GN=FAM3C PE=1 SV=1 8.75 2331.8 - 3.92E+06 - - - -0.5023 - 2.055 0.424 - 358.1 1 2 0 -0.0005 10 0 0 0 2.33E+08 1.61E+08 - - - 4.183 0.9452 221125_WJC_METTL3_EV_vs_WT_F03.10959.10959.2 1.9 12-May R.FSGVPDR.F "sp|A0A075B6R9|KVD24_HUMAN,sp|A0A0C4DH68|KV224_HUMAN,sp|A2NJV5|KV229_HUMAN,sp|A0A075B6S2|KVD29_HUMAN,sp|A0A0A0MRZ7|KVD26_HUMAN" 5 776.3817 1.75 27629 10959 2 776.381696 389.1981 Probable non-functional immunoglobulin kappa variable 2D-24 OS=Homo sapiens OX=9606 GN=IGKV2D-24 PE=1 SV=1 5.84 2332 - 999459 - - - -0.009 - 1.211 0.038 - 73.3 9 2 0 0 7 0 0 0 6.32E+07 3.60E+07 - - - -0.498 0.9988 221125_WJC_METTL3_EV_vs_WT_F03.10961.10961.2 0.0301 16-Sep K.TIAPALVSK[136.11].K "sp|P06733|ENOA_HUMAN,tr|K7ERS8|K7ERS8_HUMAN,tr|K7EM90|K7EM90_HUMAN,tr|A0A2R8Y879|A0A2R8Y879_HUMAN,tr|A0A2R8Y6I8|A0A2R8Y6I8_HUMAN,tr|A0A2R8YEM5|A0A2R8YEM5_HUMAN" 6 906.563 1.39 27630 10961 2 906.562357 454.2888 Alpha-enolase OS=Homo sapiens OX=9606 GN=ENO1 PE=1 SV=2 8.41 2332.2 - 5.54E+06 - - - -0.674 - 1.455 0.294 - 197.2 1 2 0 -0.0006 9 0 0 0 2.32E+08 1.67E+08 - - - 2.2972 0.9982 221125_WJC_METTL3_EV_vs_WT_F03.10963.10963.2 0.00608 18-Sep R.TIAQAVYGAK.D "sp|Q6UB35|C1TM_HUMAN,tr|A0A087WVM4|A0A087WVM4_HUMAN,tr|B7ZM99|B7ZM99_HUMAN" 3 1020.5604 0.67 27632 10963 2 1020.561173 511.2875 "Monofunctional C1-tetrahydrofolate synthase, mitochondrial OS=Homo sapiens OX=9606 GN=MTHFD1L PE=1 SV=1" 8.26 2332.4 - 2.34E+06 - - - 0.7623 - 1.319 0.301 - 134.7 1 2 0 0.0008 10 0 0 0 6.08E+07 9.15E+07 - - - 2.0368 0.9994 221125_WJC_METTL3_EV_vs_WT_F03.10964.10964.2 0.00717 18-Dec K.IINNTENLVR[166.11].E sp|Q9Y617|SERC_HUMAN 1 1194.6596 0.55 27633 10964 2 1194.659489 598.3371 Phosphoserine aminotransferase OS=Homo sapiens OX=9606 GN=PSAT1 PE=1 SV=2 6 2332.5 - 986707 - - - -0.0979 - 2.1 0.244 - 350.7 1 2 0 -0.0001 10 0 0 0 1.88E+07 3.44E+07 - - - 2.9141 0.9671 221125_WJC_METTL3_EV_vs_WT_F03.10966.10966.2 4.43 14-Jul K.GITLSVRP.- tr|A0A075B6Z2|A0A075B6Z2_HUMAN 1 841.5022 1314987.32 27634 10966 2 841.502582 421.7584 T cell receptor alpha joining 56 (Fragment) OS=Homo sapiens OX=9606 GN=TRAJ56 PE=4 SV=1 9.75 2332.7 - 3.94E+07 - - - 0.511 - 1.313 0.022 - 184.4 2 2 0 0.0004 8 0 0 0 7.30E+11 5.55E+05 - - - -0.1098 0.9856 221125_WJC_METTL3_EV_vs_WT_F03.10972.10972.2 0.585 16-May K.AVLGTSNFK.V "sp|P02786|TFR1_HUMAN,tr|G3V0E5|G3V0E5_HUMAN" 2 935.5076 0.41 27637 10972 2 935.508954 468.7611 Transferrin receptor protein 1 OS=Homo sapiens OX=9606 GN=TFRC PE=1 SV=2 8.8 2333.4 - 1.18E+06 - - - 1.4131 - 1.175 0.222 - 58.1 10 2 0 0.0013 9 0 0 0 3.70E+07 9.06E+07 - - - 0.7001 0.9996 221125_WJC_METTL3_EV_vs_WT_F03.10976.10976.2 0.00391 16-Aug R.SLVGLGGTK.S sp|P35908|K22E_HUMAN 1 830.4862 69.41 27639 10976 2 830.485993 416.2504 "Keratin, type II cytoskeletal 2 epidermal OS=Homo sapiens OX=9606 GN=KRT2 PE=1 SV=2" 8.47 2333.9 - 1.27E+07 - - - -0.2107 - 1.647 0.385 - 194.7 1 2 0 -0.0002 9 0 0 0 8.20E+09 1.18E+08 - - - 3.3281 0.9919 221125_WJC_METTL3_EV_vs_WT_F03.10977.10977.2 0.325 18-Jun R.GLVSSDELAK.D "sp|Q13813|SPTN1_HUMAN,tr|A0A0D9SF54|A0A0D9SF54_HUMAN,tr|A0A0D9SGF6|A0A0D9SGF6_HUMAN" 3 1017.5342 0.85 27640 10977 2 1017.533834 509.7744 "Spectrin alpha chain, non-erythrocytic 1 OS=Homo sapiens OX=9606 GN=SPTAN1 PE=1 SV=3" 4.37 2333.9 - 1.96E+06 - - - -0.399 - 1.193 0.168 - 94.3 1 2 0 -0.0004 10 0 0 0 1.22E+08 1.43E+08 - - - 0.7743 0.9973 221125_WJC_METTL3_EV_vs_WT_F03.10978.10978.2 0.104 16-Aug K.LASLEELKR.Q sp|P15924|DESP_HUMAN 1 1057.6132 46.1 27641 10978 2 1057.611983 529.8139 Desmoplakin OS=Homo sapiens OX=9606 GN=DSP PE=1 SV=3 6.14 2334 - 1.31E+06 - - - -1.1119 - 1.672 0.163 - 214.2 1 2 0 -0.0012 9 0 0 0 4.38E+07 9.51E+05 - - - 1.7316 0.9969 221125_WJC_METTL3_EV_vs_WT_F03.10979.10979.2 0.116 14-Jul R.DLYDAGVK.R "sp|P07355|ANXA2_HUMAN,sp|A6NMY6|AXA2L_HUMAN,tr|H0YL33|H0YL33_HUMAN,tr|H0YMU9|H0YMU9_HUMAN,tr|H0YM50|H0YM50_HUMAN,tr|H0YMD0|H0YMD0_HUMAN,tr|H0YMW4|H0YMW4_HUMAN,tr|H0YN42|H0YN42_HUMAN,tr|H0YN28|H0YN28_HUMAN,tr|H0YNP5|H0YNP5_HUMAN" 10 879.4338 0.29 27642 10979 2 879.43225 440.7242 Annexin A2 OS=Homo sapiens OX=9606 GN=ANXA2 PE=1 SV=2 4.21 2334 - 1.25E+06 - - - -1.7602 - 1.386 0.257 - 152.1 1 2 0 -0.0015 8 0 0 0 6.64E+07 2.32E+08 - - - 1.9232 0.9979 221125_WJC_METTL3_EV_vs_WT_F03.10982.10982.2 0.364 12-Jul K.TWQANLR.L "sp|P06730|IF4E_HUMAN,tr|H0Y8J7|H0Y8J7_HUMAN,tr|D6RBW1|D6RBW1_HUMAN" 3 887.4614 0.02 27644 10982 2 887.461065 444.738 Eukaryotic translation initiation factor 4E OS=Homo sapiens OX=9606 GN=EIF4E PE=1 SV=2 9.41 2334.3 - 1.49E+07 - - - -0.3211 - 1.507 0.19 - 326 1 2 0 -0.0003 7 0 0 0 6.03E+08 3.32E+10 - - - 1.7437 0.9977 221125_WJC_METTL3_EV_vs_WT_F03.10984.10984.2 0.0888 12-Jun R.GGFNTFR.D "sp|P17844|DDX5_HUMAN,tr|J3KTA4|J3KTA4_HUMAN,tr|A0A0G2JLI4|A0A0G2JLI4_HUMAN" 3 797.382 1.15 27645 10984 2 797.380917 399.6983 Probable ATP-dependent RNA helicase DDX5 OS=Homo sapiens OX=9606 GN=DDX5 PE=1 SV=1 9.75 2334.6 - 3.05E+06 - - - -1.4046 - 1.278 0.292 - 116.2 1 2 0 -0.0011 7 0 0 0 3.04E+08 2.65E+08 - - - 1.9746 0.9988 221125_WJC_METTL3_EV_vs_WT_F03.10985.10985.2 0.0221 12-Jun R.GGFNTFR[166.11].D "sp|P17844|DDX5_HUMAN,tr|J3KTA4|J3KTA4_HUMAN,tr|A0A0G2JLI4|A0A0G2JLI4_HUMAN" 3 807.3903 1.21 27646 10985 2 807.390078 404.7024 Probable ATP-dependent RNA helicase DDX5 OS=Homo sapiens OX=9606 GN=DDX5 PE=1 SV=1 9.75 2334.6 - 2.55E+06 - - - -0.2836 - 1.347 0.304 - 106.8 1 2 0 -0.0002 7 0 0 0 3.01E+08 2.48E+08 - - - 2.2301 0.9957 221125_WJC_METTL3_EV_vs_WT_F03.10992.10992.2 0.375 14-Jul K.AVIDLNNR[166.11].W sp|Q01081|U2AF1_HUMAN 1 923.5064 0.59 27651 10992 2 923.505248 462.7605 Splicing factor U2AF 35 kDa subunit OS=Homo sapiens OX=9606 GN=U2AF1 PE=1 SV=3 5.88 2335.3 - 3.16E+06 - - - -1.2474 - 1.606 0.13 - 161.2 1 2 0 -0.0012 8 0 0 0 2.36E+08 3.98E+08 - - - 1.4296 0.9994 221125_WJC_METTL3_EV_vs_WT_F03.10993.10993.2 0.146 16-Jul R.VQLVVGDGR.M "sp|P22061|PIMT_HUMAN,tr|F6S8N6|F6S8N6_HUMAN,tr|A0A3F2YNX8|A0A3F2YNX8_HUMAN,tr|A0A0A0MRJ6|A0A0A0MRJ6_HUMAN" 4 941.5294 0.7 27652 10993 2 941.529304 471.772 Protein-L-isoaspartate(D-aspartate) O-methyltransferase OS=Homo sapiens OX=9606 GN=PCMT1 PE=1 SV=4 5.81 2335.3 - 3.41E+06 - - - -0.1338 - 1.692 0.313 - 139.7 1 2 0 -0.0001 9 0 0 0 1.64E+08 2.35E+08 - - - 2.8743 0.9999 221125_WJC_METTL3_EV_vs_WT_F03.10994.10994.2 5.42E-05 18-Nov K.IVQMTEAEVR.G "sp|P62140|PP1B_HUMAN,tr|C9JP48|C9JP48_HUMAN,tr|C9J9S3|C9J9S3_HUMAN" 3 1174.6016 1 27653 10994 2 1174.601488 588.3081 Serine\threonine-protein phosphatase PP1-beta catalytic subunit OS=Homo sapiens OX=9606 GN=PPP1CB PE=1 SV=3 4.53 2335.4 - 1.41E+06 - - - -0.1022 - 2.405 0.519 - 570.8 1 2 0 -0.0001 10 0 0 0 5.22E+07 5.20E+07 - - - 5.3238 0.9997 221125_WJC_METTL3_EV_vs_WT_F03.10995.10995.2 0.000445 16-Oct K.TPLTATLSK.S "sp|P01876|IGHA1_HUMAN,tr|A0A286YEY1|A0A286YEY1_HUMAN" 2 930.5386 220.21 27654 10995 2 930.53931 466.2766 Immunoglobulin heavy constant alpha 1 OS=Homo sapiens OX=9606 GN=IGHA1 PE=1 SV=2 8.41 2335.5 - 1.40E+06 - - - 0.7662 - 1.606 0.438 - 351.5 1 2 0 0.0007 9 0 0 0 2.54E+08 1.15E+06 - - - 3.6464 0.9991 221125_WJC_METTL3_EV_vs_WT_F03.10996.10996.2 0.00107 18-Oct K.IVQMTEAEVR[166.11].G "sp|P62140|PP1B_HUMAN,tr|C9JP48|C9JP48_HUMAN,tr|C9J9S3|C9J9S3_HUMAN" 3 1184.6099 1.01 27655 10996 2 1184.606025 593.3122 Serine\threonine-protein phosphatase PP1-beta catalytic subunit OS=Homo sapiens OX=9606 GN=PPP1CB PE=1 SV=3 4.53 2335.6 - 990170 - - - -3.2525 - 2.203 0.41 - 345.3 1 2 0 -0.0039 10 0 0 0 5.24E+07 5.20E+07 - - - 4.2727 0.996 221125_WJC_METTL3_EV_vs_WT_F03.10998.10998.2 0.000372 24-Oct K.IIGDASTQTDALK.L "sp|Q5VZL5|ZMYM4_HUMAN,tr|H7C1I7|H7C1I7_HUMAN" 2 1331.6933 0.45 27657 10998 2 1331.699956 666.8539 Zinc finger MYM-type protein 4 OS=Homo sapiens OX=9606 GN=ZMYM4 PE=1 SV=1 4.21 2335.9 - 250561 - - - 5.0282 - 1.718 0.497 - 183.1 1 2 0 0.0067 13 0 0 0 5.40E+06 1.21E+07 - - - 4.0986 0.9995 221125_WJC_METTL3_EV_vs_WT_F03.11001.11001.2 0.061 16-Sep R.VQLVVGDGR[166.11].M "sp|P22061|PIMT_HUMAN,tr|F6S8N6|F6S8N6_HUMAN,tr|A0A3F2YNX8|A0A3F2YNX8_HUMAN,tr|A0A0A0MRJ6|A0A0A0MRJ6_HUMAN" 4 951.5377 0.7 27658 11001 2 951.53654 476.7761 Protein-L-isoaspartate(D-aspartate) O-methyltransferase OS=Homo sapiens OX=9606 GN=PCMT1 PE=1 SV=4 5.81 2336.2 - 7.83E+06 - - - -1.2191 - 1.903 0.316 - 396.8 1 2 0 -0.0012 9 0 0 0 1.64E+08 2.35E+08 - - - 3.2361 0.9994 221125_WJC_METTL3_EV_vs_WT_F03.11002.11002.2 0.000861 18-Sep R.QAGLLTTDPR.V sp|P82933|RT09_HUMAN 1 1070.572 0.61 27659 11002 2 1070.573315 536.2933 "28S ribosomal protein S9, mitochondrial OS=Homo sapiens OX=9606 GN=MRPS9 PE=1 SV=2" 5.84 2336.3 - 2.81E+06 - - - 1.2068 - 1.671 0.384 - 192.6 1 2 0 0.0013 10 0 0 0 8.41E+07 1.39E+08 - - - 3.3099 0.992 221125_WJC_METTL3_EV_vs_WT_F03.11003.11003.2 0.0631 14-Aug R.ITTMQLER[166.11].E sp|Q14152|EIF3A_HUMAN 1 1000.5251 -1 27660 11003 2 1000.523743 501.2698 Eukaryotic translation initiation factor 3 subunit A OS=Homo sapiens OX=9606 GN=EIF3A PE=1 SV=1 6 2336.4 - 2.39E+06 - - - -1.3423 - 1.649 0.063 - 199.8 1 2 0 -0.0013 8 0 0 0 0.00E+00 0.00E+00 - - - 1.0144 0.9555 221125_WJC_METTL3_EV_vs_WT_F03.11004.11004.2 0.372 16-Aug K.ATLSAEVYR.L "sp|Q9H8H0|NOL11_HUMAN,tr|J3QLQ6|J3QLQ6_HUMAN" 2 1008.524 0.6 27661 11004 2 1008.524625 505.2693 Nucleolar protein 11 OS=Homo sapiens OX=9606 GN=NOL11 PE=1 SV=1 6.05 2336.4 - 1.78E+06 - - - 0.6098 - 1.259 0.001 - 194.3 1 2 0 0.0006 9 0 0 0 5.47E+07 9.19E+07 - - - -0.2855 0.9996 221125_WJC_METTL3_EV_vs_WT_F03.11008.11008.2 0.00029 18-Oct K.ATAVVDGAFK[136.11].E "sp|P32119|PRDX2_HUMAN,tr|A6NIW5|A6NIW5_HUMAN" 2 985.5324 0.85 27664 11008 2 985.531833 493.7735 Peroxiredoxin-2 OS=Homo sapiens OX=9606 GN=PRDX2 PE=1 SV=5 5.88 2336.8 - 1.41E+07 - - - -0.5713 - 1.95 0.34 - 449.1 1 2 0 -0.0006 10 0 0 0 4.76E+08 5.62E+08 - - - 3.4162 0.9983 221125_WJC_METTL3_EV_vs_WT_F03.11010.11010.2 0.0516 14-Jul K.AVIDLNNR.W sp|Q01081|U2AF1_HUMAN 1 913.4981 0.54 27665 11010 2 913.496149 457.7563 Splicing factor U2AF 35 kDa subunit OS=Homo sapiens OX=9606 GN=U2AF1 PE=1 SV=3 5.88 2337 - 4.73E+06 - - - -2.1686 - 1.527 0.323 - 164.1 1 2 0 -0.002 8 0 0 0 2.41E+08 4.45E+08 - - - 2.7027 0.818 221125_WJC_METTL3_EV_vs_WT_F03.11011.11011.2 0.127 20-Jun L.PNEAGLQDEKK.V sp|Q6NT55|CP4FN_HUMAN 1 1227.6095 999 27666 11011 2 1227.607596 614.812 Ultra-long-chain fatty acid omega-hydroxylase OS=Homo sapiens OX=9606 GN=CYP4F22 PE=1 SV=1 4.68 2337.2 - 423838 - - - -1.5762 - 1.328 0.255 - 108.9 1 1 0 -0.0019 11 0 0 0 6.57E+07 0.00E+00 - - - 1.6912 0.9999 221125_WJC_METTL3_EV_vs_WT_F03.11012.11012.2 1.64E-07 13/24 K.VVVVTGANTGIGK.E "sp|Q8TC12|RDH11_HUMAN,tr|G3V234|G3V234_HUMAN,tr|G3V2G6|G3V2G6_HUMAN" 3 1213.703 0.96 27667 11012 2 1213.702559 607.8588 Retinol dehydrogenase 11 OS=Homo sapiens OX=9606 GN=RDH11 PE=1 SV=2 8.72 2337.3 - 573758 - - - -0.3938 - 2.72 0.509 - 515.2 1 2 0 -0.0005 13 0 0 0 5.98E+07 6.24E+07 - - - 5.3685 0.8573 221125_WJC_METTL3_EV_vs_WT_F03.11017.11017.2 0.0725 14-May R.YPDGIISK.P sp|Q86U44|MTA70_HUMAN 1 891.4702 0.02 27670 11017 2 891.470316 446.7424 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 5.83 2337.9 - 6.39E+06 - - - 0.1492 - 1.267 0.243 - 61.8 1 1 0 0.0001 8 0 0 0 1.60E+09 7.37E+10 - - - 1.5495 0.9999 221125_WJC_METTL3_EV_vs_WT_F03.11018.11018.2 0.0012 18-Dec R.QENGASVILR.D "sp|P29692|EF1D_HUMAN,tr|E9PI39|E9PI39_HUMAN,tr|E9PMW7|E9PMW7_HUMAN,tr|E9PQ49|E9PQ49_HUMAN,tr|A0A087X1X7|A0A087X1X7_HUMAN,tr|E9PL12|E9PL12_HUMAN,tr|E9PK72|E9PK72_HUMAN,tr|H0YCK7|H0YCK7_HUMAN,tr|E9PK06|E9PK06_HUMAN,tr|E9PIZ1|E9PIZ1_HUMAN,tr|E9PPR1|E9PPR1_HUMAN,tr|E9PRY8|E9PRY8_HUMAN,tr|E9PK01|E9PK01_HUMAN" 13 1085.5829 1.59 27671 11018 2 1085.582891 543.7987 Elongation factor 1-delta OS=Homo sapiens OX=9606 GN=EEF1D PE=1 SV=5 6 2337.9 - 5.36E+06 - - - -0.0286 - 2.33 0.45 - 835.9 1 2 0 0 10 0 0 0 2.35E+08 1.47E+08 - - - 4.7258 0.9998 221125_WJC_METTL3_EV_vs_WT_F03.11019.11019.2 7.16E-06 24-Nov K.VVVVTGANTGIGK[136.11].E "sp|Q8TC12|RDH11_HUMAN,tr|G3V234|G3V234_HUMAN,tr|G3V2G6|G3V2G6_HUMAN" 3 1221.7172 0.96 27672 11019 2 1221.715516 611.8659 Retinol dehydrogenase 11 OS=Homo sapiens OX=9606 GN=RDH11 PE=1 SV=2 8.72 2338 - 1.64E+06 - - - -1.4087 - 2.279 0.465 - 336.6 1 2 0 -0.0017 13 0 0 0 5.98E+07 6.24E+07 - - - 4.5891 0.9996 221125_WJC_METTL3_EV_vs_WT_F03.11023.11023.2 0.0462 16-Sep R.VIGSELVQK[136.11].Y "sp|P35998|PRS7_HUMAN,tr|C9JX88|C9JX88_HUMAN" 2 979.5793 0.65 27674 11023 2 979.579429 490.7969 26S proteasome regulatory subunit 7 OS=Homo sapiens OX=9606 GN=PSMC2 PE=1 SV=3 5.97 2338.6 - 5.12E+06 - - - 0.0837 - 1.781 0.339 - 210.7 1 2 0 0.0001 9 0 0 0 8.23E+07 1.26E+08 - - - 3.2146 0.9997 221125_WJC_METTL3_EV_vs_WT_F03.11024.11024.2 0.000353 18-Oct R.GLVSSDELAK[136.11].D "sp|Q13813|SPTN1_HUMAN,tr|A0A0D9SF54|A0A0D9SF54_HUMAN,tr|A0A0D9SGF6|A0A0D9SGF6_HUMAN" 3 1025.5484 0.78 27675 11024 2 1025.546801 513.7815 "Spectrin alpha chain, non-erythrocytic 1 OS=Homo sapiens OX=9606 GN=SPTAN1 PE=1 SV=3" 4.37 2338.6 - 2.83E+06 - - - -1.5982 - 1.893 0.447 - 325.7 1 2 0 -0.0016 10 0 0 0 1.22E+08 1.56E+08 - - - 4.1233 0.9991 221125_WJC_METTL3_EV_vs_WT_F03.11026.11026.2 0.0212 16-Oct R.AAVLLEQER[166.11].Q "sp|Q13435|SF3B2_HUMAN,tr|E9PPJ0|E9PPJ0_HUMAN,tr|H0YCG1|H0YCG1_HUMAN,tr|E9PJ04|E9PJ04_HUMAN,tr|E9PJT3|E9PJT3_HUMAN" 5 1037.5745 1.05 27677 11026 2 1037.572813 519.7945 Splicing factor 3B subunit 2 OS=Homo sapiens OX=9606 GN=SF3B2 PE=1 SV=2 4.53 2338.8 - 1.25E+06 - - - -1.6057 - 1.961 0.259 - 479.4 1 2 0 -0.0017 9 0 0 0 1.94E+08 1.85E+08 - - - 2.9018 0.9988 221125_WJC_METTL3_EV_vs_WT_F03.11029.11029.2 0.000232 12-Jul K.YGLNMC[160.03]R[166.11].Q "sp|P62273|RS29_HUMAN,tr|A0A2R8Y6P7|A0A2R8Y6P7_HUMAN,tr|A0A2R8Y851|A0A2R8Y851_HUMAN,tr|A0A087WTT6|A0A087WTT6_HUMAN" 4 922.4029 0.99 27678 11029 2 922.400272 462.2087 40S ribosomal protein S29 OS=Homo sapiens OX=9606 GN=RPS29 PE=1 SV=2 8.22 2339.2 - 2.09E+07 - - - -2.809 - 1.55 0.417 - 173.6 1 2 0 -0.0026 7 0 0 0 4.88E+09 4.94E+09 - - - 3.5088 0.9304 221125_WJC_METTL3_EV_vs_WT_F03.11031.11031.3 0.462 Sep-48 K.LLYNRPGTVSSLK.K "sp|P35659|DEK_HUMAN,tr|H0Y8X0|H0Y8X0_HUMAN,tr|H0Y993|H0Y993_HUMAN,tr|A0A494C028|A0A494C028_HUMAN,tr|D6RDA2|D6RDA2_HUMAN,tr|B4DFG0|B4DFG0_HUMAN" 6 1446.8195 1.74 27680 11031 3 1446.816905 483.2804 Protein DEK OS=Homo sapiens OX=9606 GN=DEK PE=1 SV=1 9.99 2339.3 - 2.25E+06 - - - -1.7687 - 1.552 0.105 - 90.1 1 2 0 -0.0026 13 0 0 0 1.54E+08 8.89E+07 - - - 0.9017 0.9987 221125_WJC_METTL3_EV_vs_WT_F03.11033.11033.2 0.0146 14-Sep R.QEQSYFVR.L sp|O60664|PLIN3_HUMAN 1 1055.5036 1.45 27682 11033 2 1055.501601 528.7591 Perilipin-3 OS=Homo sapiens OX=9606 GN=PLIN3 PE=1 SV=3 6 2339.5 - 1.54E+06 - - - -1.9024 - 1.713 0.282 - 395.6 1 2 0 -0.002 8 0 0 0 3.57E+07 2.46E+07 - - - 2.7465 0.8797 221125_WJC_METTL3_EV_vs_WT_F03.11047.11047.2 1.02 16-Sep R.ALEEALEAK[136.11].E "sp|P35580|MYH10_HUMAN,sp|P35749|MYH11_HUMAN" 2 980.527 1.02 27689 11047 2 980.521401 491.2708 Myosin-10 OS=Homo sapiens OX=9606 GN=MYH10 PE=1 SV=3 4.25 2341.1 - 6.48E+06 - - - -5.6867 - 1.344 0.177 - 176.1 1 2 0 -0.0056 9 0 0 0 4.40E+08 4.29E+08 - - - 1.2019 0.9998 221125_WJC_METTL3_EV_vs_WT_F03.11049.11049.2 0.0126 13/18 R.AATENIPVVR.R "sp|Q6P1J9|CDC73_HUMAN,tr|A0A2R8Y640|A0A2R8Y640_HUMAN,tr|A0A2R8YHB3|A0A2R8YHB3_HUMAN,tr|A0A1B0GUB2|A0A1B0GUB2_HUMAN,tr|A0A3B3IRP5|A0A3B3IRP5_HUMAN" 5 1068.5928 1.04 27691 11049 2 1068.592916 535.3037 Parafibromin OS=Homo sapiens OX=9606 GN=CDC73 PE=1 SV=1 6.05 2341.3 - 1.78E+06 - - - 0.1479 - 2.13 0.396 - 633.4 1 2 0 0.0002 10 0 0 0 1.77E+08 1.70E+08 - - - 4.0764 0.9994 221125_WJC_METTL3_EV_vs_WT_F03.11053.11053.2 0.000723 16-Oct K.VSESVIDVK.T "sp|P82094|TMF1_HUMAN,tr|F8WF45|F8WF45_HUMAN,tr|A0A2R8Y7M0|A0A2R8Y7M0_HUMAN" 3 974.5284 1.25 27693 11053 2 974.525748 488.2715 TATA element modulatory factor OS=Homo sapiens OX=9606 GN=TMF1 PE=1 SV=2 4.37 2341.7 - 6.11E+06 - - - -2.749 - 2.338 0.396 - 295.7 1 2 0 -0.0027 9 0 0 0 4.11E+08 3.29E+08 - - - 4.4221 0.9997 221125_WJC_METTL3_EV_vs_WT_F03.11054.11054.2 0.00518 14-Aug R.SVSDQFYR.Y "sp|P55010|IF5_HUMAN,tr|H0YM54|H0YM54_HUMAN,tr|H0YLZ1|H0YLZ1_HUMAN,tr|H0YMJ8|H0YMJ8_HUMAN,tr|H0YK11|H0YK11_HUMAN,tr|H0YK29|H0YK29_HUMAN,tr|H0YN40|H0YN40_HUMAN" 7 1000.4614 1.29 27694 11054 2 1000.461425 501.238 Eukaryotic translation initiation factor 5 OS=Homo sapiens OX=9606 GN=EIF5 PE=1 SV=2 5.55 2341.8 - 2.06E+06 - - - 0.015 - 1.701 0.396 - 190.5 1 2 0 0 8 0 0 0 1.50E+08 1.16E+08 - - - 3.568 0.9998 221125_WJC_METTL3_EV_vs_WT_F03.11062.11062.2 7.99E-05 18-Nov R.QENGASVILR[166.11].D "sp|P29692|EF1D_HUMAN,tr|E9PI39|E9PI39_HUMAN,tr|E9PMW7|E9PMW7_HUMAN,tr|E9PQ49|E9PQ49_HUMAN,tr|A0A087X1X7|A0A087X1X7_HUMAN,tr|E9PL12|E9PL12_HUMAN,tr|E9PK72|E9PK72_HUMAN,tr|H0YCK7|H0YCK7_HUMAN,tr|E9PK06|E9PK06_HUMAN,tr|E9PIZ1|E9PIZ1_HUMAN,tr|E9PPR1|E9PPR1_HUMAN,tr|E9PRY8|E9PRY8_HUMAN,tr|E9PK01|E9PK01_HUMAN" 13 1095.5912 1.59 27698 11062 2 1095.590266 548.8029 Elongation factor 1-delta OS=Homo sapiens OX=9606 GN=EEF1D PE=1 SV=5 6 2342.8 - 3.09E+06 - - - -0.8452 - 2.189 0.461 - 677.2 1 2 0 -0.0009 10 0 0 0 2.34E+08 1.47E+08 - - - 4.6325 0.9734 221125_WJC_METTL3_EV_vs_WT_F03.11066.11066.2 0.695 16-Jun R.AGAPLPVPR.G sp|Q92908|GATA6_HUMAN 1 876.5181 4.95 27701 11066 2 876.518355 439.2663 Transcription factor GATA-6 OS=Homo sapiens OX=9606 GN=GATA6 PE=1 SV=2 9.79 2343.1 - 2.30E+06 - - - 0.2487 - 1.121 0.102 - 110.4 2 2 0 0.0002 9 0 0 0 2.41E+08 4.87E+07 - - - -0.0097 0.9997 221125_WJC_METTL3_EV_vs_WT_F03.11069.11069.2 0.00344 14-Aug R.SVSDQFYR[166.11].Y "sp|P55010|IF5_HUMAN,tr|H0YM54|H0YM54_HUMAN,tr|H0YLZ1|H0YLZ1_HUMAN,tr|H0YMJ8|H0YMJ8_HUMAN,tr|H0YK11|H0YK11_HUMAN,tr|H0YK29|H0YK29_HUMAN,tr|H0YN40|H0YN40_HUMAN" 7 1010.4697 1.29 27702 11069 2 1010.468943 506.2421 Eukaryotic translation initiation factor 5 OS=Homo sapiens OX=9606 GN=EIF5 PE=1 SV=2 5.55 2343.5 - 4.29E+06 - - - -0.7294 - 1.581 0.43 - 195.4 1 2 0 -0.0007 8 0 0 0 1.50E+08 1.16E+08 - - - 3.5982 0.9176 221125_WJC_METTL3_EV_vs_WT_F03.11070.11070.2 0.019 20-Aug G.QQSLLAFAEQR[166.11].A sp|Q9Y3R4|NEUR2_HUMAN 1 1299.6811 0.6 27703 11070 2 1299.679423 650.8478 Sialidase-2 OS=Homo sapiens OX=9606 GN=NEU2 PE=1 SV=2 6 2343.7 - 1.28E+06 - - - -1.2672 - 1.53 0.284 - 190.7 1 1 0 -0.0016 11 0 0 0 1.47E+08 2.46E+08 - - - 2.2886 0.8568 221125_WJC_METTL3_EV_vs_WT_F03.11073.11073.2 0.0112 14-Jul L.ASFGLSAR.D "sp|P43243|MATR3_HUMAN,tr|A8MXP9|A8MXP9_HUMAN,tr|D6R991|D6R991_HUMAN,tr|A0A0R4J2E8|A0A0R4J2E8_HUMAN,tr|D6REM6|D6REM6_HUMAN" 5 807.4239 1.1 27704 11073 2 807.422243 404.7192 Matrin-3 OS=Homo sapiens OX=9606 GN=MATR3 PE=1 SV=2 9.79 2344.1 - 4.59E+06 - - - -2.0547 - 1.475 0.267 - 149.9 1 1 0 -0.0017 8 0 0 0 1.04E+08 9.48E+07 - - - 2.1847 0.7841 221125_WJC_METTL3_EV_vs_WT_F03.11076.11076.2 0.111 20-Aug G.QQSLLAFAEQR.A sp|Q9Y3R4|NEUR2_HUMAN 1 1289.6728 0.6 27706 11076 2 1289.675262 645.8437 Sialidase-2 OS=Homo sapiens OX=9606 GN=NEU2 PE=1 SV=2 6 2344.4 - 1.66E+06 - - - 1.909 - 1.422 0.239 - 228.2 1 1 0 0.0025 11 0 0 0 1.47E+08 2.46E+08 - - - 1.7579 0.999 221125_WJC_METTL3_EV_vs_WT_F03.11077.11077.2 5.42E-05 22-Oct K.EGNGTVMGAELR[166.11].H "sp|P08590|MYL3_HUMAN,sp|P05976|MYL1_HUMAN,sp|P60660|MYL6_HUMAN,tr|F8W1R7|F8W1R7_HUMAN,tr|G3V1V0|G3V1V0_HUMAN,tr|B7Z6Z4|B7Z6Z4_HUMAN,tr|F8VZU9|F8VZU9_HUMAN,tr|G8JLA2|G8JLA2_HUMAN,tr|H0YI43|H0YI43_HUMAN,tr|F8W180|F8W180_HUMAN,tr|G3V1Y7|G3V1Y7_HUMAN,tr|J3KND3|J3KND3_HUMAN,tr|F8VPF3|F8VPF3_HUMAN" 13 1242.5902 1.28 27707 11077 2 1242.586015 622.3024 Myosin light chain 3 OS=Homo sapiens OX=9606 GN=MYL3 PE=1 SV=3 4.53 2344.5 - 1.60E+06 - - - -3.3728 - 2.071 0.46 - 342.9 1 2 0 -0.0042 12 0 0 0 7.88E+07 6.15E+07 - - - 4.3528 0.9984 221125_WJC_METTL3_EV_vs_WT_F03.11078.11078.2 0.056 18-Oct R.LSTASVIQAR[166.11].Y sp|Q96JB3|HIC2_HUMAN 1 1054.601 0.94 27708 11078 2 1054.59796 528.3078 Hypermethylated in cancer 2 protein OS=Homo sapiens OX=9606 GN=HIC2 PE=1 SV=2 9.75 2344.6 - 1.02E+06 - - - -2.9092 - 2.079 0.303 - 314.9 1 2 0 -0.0031 10 0 0 0 1.71E+07 1.82E+07 - - - 3.3209 0.9994 221125_WJC_METTL3_EV_vs_WT_F03.11082.11082.2 0.0183 14-Jul K.VNENELLR[166.11].Q "sp|Q15643|TRIPB_HUMAN,tr|H0YJ97|H0YJ97_HUMAN" 2 995.5275 4.23 27710 11082 2 995.526272 498.771 Thyroid receptor-interacting protein 11 OS=Homo sapiens OX=9606 GN=TRIP11 PE=1 SV=3 4.53 2345.1 - 5.71E+06 - - - -1.2626 - 1.698 0.342 - 184.5 1 2 0 -0.0013 8 0 0 0 1.32E+09 3.11E+08 - - - 3.1634 0.9986 221125_WJC_METTL3_EV_vs_WT_F03.11083.11083.2 7.15E-05 18-Oct R.AATENIPVVR[166.11].R "sp|Q6P1J9|CDC73_HUMAN,tr|A0A2R8Y640|A0A2R8Y640_HUMAN,tr|A0A2R8YHB3|A0A2R8YHB3_HUMAN,tr|A0A1B0GUB2|A0A1B0GUB2_HUMAN,tr|A0A3B3IRP5|A0A3B3IRP5_HUMAN" 5 1078.601 1.15 27711 11083 2 1078.596443 540.3078 Parafibromin OS=Homo sapiens OX=9606 GN=CDC73 PE=1 SV=1 6.05 2345.1 - 3.37E+06 - - - -4.2509 - 2.122 0.487 - 378.4 1 2 0 -0.0046 10 0 0 0 2.56E+08 2.24E+08 - - - 4.7366 0.9992 221125_WJC_METTL3_EV_vs_WT_F03.11089.11089.2 8.06E-07 13/22 K.EGNGTVMGAELR.H "sp|P08590|MYL3_HUMAN,sp|P05976|MYL1_HUMAN,sp|P60660|MYL6_HUMAN,tr|F8W1R7|F8W1R7_HUMAN,tr|G3V1V0|G3V1V0_HUMAN,tr|B7Z6Z4|B7Z6Z4_HUMAN,tr|F8VZU9|F8VZU9_HUMAN,tr|G8JLA2|G8JLA2_HUMAN,tr|H0YI43|H0YI43_HUMAN,tr|F8W180|F8W180_HUMAN,tr|G3V1Y7|G3V1Y7_HUMAN,tr|J3KND3|J3KND3_HUMAN,tr|F8VPF3|F8VPF3_HUMAN" 13 1232.5819 1.24 27715 11089 2 1232.577873 617.2982 Myosin light chain 3 OS=Homo sapiens OX=9606 GN=MYL3 PE=1 SV=3 4.53 2345.9 - 1.74E+06 - - - -3.2963 - 2.202 0.465 - 590.5 1 2 0 -0.0041 12 0 0 0 6.72E+07 5.40E+07 - - - 4.5512 0.9994 221125_WJC_METTL3_EV_vs_WT_F03.11090.11090.2 0.0119 16-Aug R.GLTSVINQK.L "sp|P07195|LDHB_HUMAN,tr|A0A5F9ZHM4|A0A5F9ZHM4_HUMAN" 2 958.5447 0.63 27716 11090 2 958.54548 480.2796 L-lactate dehydrogenase B chain OS=Homo sapiens OX=9606 GN=LDHB PE=1 SV=2 8.75 2346.1 - 2.58E+06 - - - 0.7668 - 1.842 0.31 - 224.6 1 2 0 0.0007 9 0 0 0 6.86E+07 1.08E+08 - - - 3.0977 0.7745 221125_WJC_METTL3_EV_vs_WT_F03.11094.11094.2 0.482 16-Sep R.VIQYLTSNK[136.11].C "sp|O15381|NVL_HUMAN,tr|E9PH71|E9PH71_HUMAN,tr|F8WF01|F8WF01_HUMAN,tr|E7EWK7|E7EWK7_HUMAN,tr|E9PGD8|E9PGD8_HUMAN" 5 1072.6008 0.31 27718 11094 2 1072.591061 537.3077 Nuclear valosin-containing protein-like OS=Homo sapiens OX=9606 GN=NVL PE=1 SV=1 8.56 2346.6 - 945227 - - - -9.0891 - 1.472 0.234 - 190.5 1 2 0 -0.0097 9 0 0 0 8.72E+06 2.77E+07 - - - 1.8848 0.9977 221125_WJC_METTL3_EV_vs_WT_F03.11097.11097.2 3.45E-05 16-Sep R.GYAVLGGER[166.11].G "sp|P49327|FAS_HUMAN,tr|A0A0U1RQF0|A0A0U1RQF0_HUMAN" 2 930.4799 0.48 27719 11097 2 930.475857 466.2472 Fatty acid synthase OS=Homo sapiens OX=9606 GN=FASN PE=1 SV=3 6 2346.9 - 5.65E+06 - - - -4.2913 - 1.908 0.426 - 423.6 1 2 0 -0.004 9 0 0 0 7.56E+07 1.57E+08 - - - 4.0553 0.9956 221125_WJC_METTL3_EV_vs_WT_F03.11099.11099.2 0.0788 12-Jun R.DMFC[160.03]AGR[166.11].V sp|Q99832|TCPH_HUMAN 1 865.345 0.12 27721 11099 2 865.343123 433.6798 T-complex protein 1 subunit eta OS=Homo sapiens OX=9606 GN=CCT7 PE=1 SV=2 5.83 2347.1 - 1.18E+07 - - - -2.1841 - 1.305 0.269 - 223.6 1 2 0 -0.0019 7 0 0 0 4.22E+07 3.52E+08 - - - 1.8707 0.9704 221125_WJC_METTL3_EV_vs_WT_F03.11103.11103.2 0.234 14-Aug R.GLDISNVK[136.11].H "sp|O00571|DDX3X_HUMAN,tr|A0A2R8YFR4|A0A2R8YFR4_HUMAN,tr|A0A2R8YCW1|A0A2R8YCW1_HUMAN,tr|A0A2R8YDT5|A0A2R8YDT5_HUMAN,tr|A0A2R8Y645|A0A2R8Y645_HUMAN,tr|A0A2R8YF78|A0A2R8YF78_HUMAN,tr|A0A0D9SFB3|A0A0D9SFB3_HUMAN,tr|A0A2R8YFS5|A0A2R8YFS5_HUMAN,tr|A0A0D9SF53|A0A0D9SF53_HUMAN,tr|A0A087WVZ1|A0A087WVZ1_HUMAN,tr|A0A0J9YVQ7|A0A0J9YVQ7_HUMAN,tr|A0A2R8Y5G6|A0A2R8Y5G6_HUMAN,tr|A0A2R8Y7T2|A0A2R8Y7T2_HUMAN,tr|A0A0D9SG12|A0A0D9SG12_HUMAN,tr|F6S8Q4|F6S8Q4_HUMAN,tr|A0A2U3TZJ9|A0A2U3TZJ9_HUMAN,tr|A0A2R8Y4A4|A0A2R8Y4A4_HUMAN" 17 852.4796 1.05 27723 11103 2 852.476544 427.2471 ATP-dependent RNA helicase DDX3X OS=Homo sapiens OX=9606 GN=DDX3X PE=1 SV=3 5.84 2347.6 - 2.35E+07 - - - -3.6224 - 1.265 0.198 - 181.8 1 2 0 -0.0031 8 0 0 0 7.08E+08 6.74E+08 - - - 1.2114 0.888 221125_WJC_METTL3_EV_vs_WT_F03.11105.11105.2 0.00465 12-Aug K.EHC[160.03]LVGV.K sp|Q86U44|MTA70_HUMAN 1 812.3851 - 27724 11105 2 812.382733 407.1998 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 5.24 2347.8 - 3.53E+06 - - - -2.8816 - 1.399 0.392 - 306.8 1 1 0 -0.0023 7 0 0 0 - - - - - 2.9994 0.9987 221125_WJC_METTL3_EV_vs_WT_F03.11110.11110.2 0.000387 13/18 R.ILQNEPLPER.L "sp|O95793|STAU1_HUMAN,tr|Q5JW30|Q5JW30_HUMAN,tr|Q5JW28|Q5JW28_HUMAN,tr|F6UDC6|F6UDC6_HUMAN" 4 1207.6561 2.23 27727 11110 2 1207.651662 604.8353 Double-stranded RNA-binding protein Staufen homolog 1 OS=Homo sapiens OX=9606 GN=STAU1 PE=1 SV=2 4.53 2348.3 - 1.63E+06 - - - -3.6641 - 2.289 0.398 - 654.6 1 2 0 -0.0044 10 0 0 0 1.17E+09 5.26E+08 - - - 4.2908 0.9872 221125_WJC_METTL3_EV_vs_WT_F03.11113.11113.2 0.0187 12-Jun R.YDIDMTK.C "sp|O00217|NDUS8_HUMAN,tr|E9PPW7|E9PPW7_HUMAN,tr|E9PKH6|E9PKH6_HUMAN" 3 884.395 0.12 27730 11113 2 884.391616 443.2048 "NADH dehydrogenase [ubiquinone] iron-sulfur protein 8, mitochondrial OS=Homo sapiens OX=9606 GN=NDUFS8 PE=1 SV=1" 4.21 2348.7 - 2.29E+06 - - - -3.7924 - 1.243 0.302 - 94.7 1 2 0 -0.0034 7 0 0 0 6.67E+07 5.38E+08 - - - 1.9598 0.9963 221125_WJC_METTL3_EV_vs_WT_F03.11116.11116.2 0.0228 16-Aug R.AGAPLPVPR[166.11].G sp|Q92908|GATA6_HUMAN 1 886.5264 4.41 27731 11116 2 886.528022 444.2705 Transcription factor GATA-6 OS=Homo sapiens OX=9606 GN=GATA6 PE=1 SV=2 9.79 2349 - 1.81E+06 - - - 1.8217 - 1.386 0.257 - 197.2 1 2 0 0.0016 9 0 0 0 2.12E+08 4.81E+07 - - - 1.8831 0.989 221125_WJC_METTL3_EV_vs_WT_F03.11117.11117.2 0.000441 16-Oct N.LEAQITDVR.Q "sp|P35527|K1C9_HUMAN,tr|K7EQQ3|K7EQQ3_HUMAN" 2 1043.5611 5.04 27732 11117 2 1043.560125 522.7878 "Keratin, type I cytoskeletal 9 OS=Homo sapiens OX=9606 GN=KRT9 PE=1 SV=3" 4.37 2349.2 - 2.96E+06 - - - -0.9573 - 2.414 0.383 - 394.4 1 1 0 -0.001 9 0 0 0 9.35E+07 1.85E+07 - - - 4.4191 0.9966 221125_WJC_METTL3_EV_vs_WT_F03.11119.11119.2 0.00256 18-Dec R.ILQNEPLPER[166.11].L "sp|O95793|STAU1_HUMAN,tr|Q5JW30|Q5JW30_HUMAN,tr|Q5JW28|Q5JW28_HUMAN,tr|F6UDC6|F6UDC6_HUMAN" 4 1217.6644 2.23 27734 11119 2 1217.657763 609.8395 Double-stranded RNA-binding protein Staufen homolog 1 OS=Homo sapiens OX=9606 GN=STAU1 PE=1 SV=2 4.53 2349.4 - 1.91E+06 - - - -5.4153 - 2.209 0.465 - 566.3 1 2 0 -0.0066 10 0 0 0 1.17E+09 5.26E+08 - - - 4.6856 0.9994 221125_WJC_METTL3_EV_vs_WT_F03.11127.11127.2 0.00919 14-Aug K.DLGEENFK.A "sp|P02768|ALBU_HUMAN,tr|A0A087WWT3|A0A087WWT3_HUMAN,tr|B7WNR0|B7WNR0_HUMAN,tr|H7C013|H7C013_HUMAN,tr|A0A0C4DGB6|A0A0C4DGB6_HUMAN,tr|C9JKR2|C9JKR2_HUMAN" 6 950.4345 0.48 27737 11127 2 950.433419 476.2245 Albumin OS=Homo sapiens OX=9606 GN=ALB PE=1 SV=2 4.14 2350.6 - 3.24E+06 - - - -1.1647 - 1.424 0.401 - 158.1 1 2 0 -0.0011 8 0 0 0 6.82E+07 1.43E+08 - - - 3.0685 0.9915 221125_WJC_METTL3_EV_vs_WT_F03.11132.11132.2 0.43 12-Jun R.AQFLVEK.A "sp|Q99623|PHB2_HUMAN,tr|F5H3X6|F5H3X6_HUMAN,tr|F5GWA7|F5GWA7_HUMAN,tr|F5GY37|F5GY37_HUMAN" 4 833.4647 999 27739 11132 2 833.466043 417.7396 Prohibitin-2 OS=Homo sapiens OX=9606 GN=PHB2 PE=1 SV=2 6.05 2351.2 - 3.22E+06 - - - 1.6065 - 1.304 0.172 - 159.3 1 2 0 0.0013 7 0 0 0 1.79E+08 0.00E+00 - - - 1.152 0.947 221125_WJC_METTL3_EV_vs_WT_F03.11135.11135.2 0.000225 24-Aug R.HLLPTSGAAATAA.A "sp|Q9BWF3|RBM4_HUMAN,tr|E9PB51|E9PB51_HUMAN" 2 1179.6248 - 27742 11135 2 1179.622011 590.8197 RNA-binding protein 4 OS=Homo sapiens OX=9606 GN=RBM4 PE=1 SV=1 6.74 2351.5 - 1.53E+06 - - - -2.3533 - 1.704 0.412 - 199.2 1 1 0 -0.0028 13 0 0 0 - - - - - 3.4511 0.9497 221125_WJC_METTL3_EV_vs_WT_F03.11136.11136.2 10.9 16-Sep K.ALSTMDLQK[136.11].V "sp|Q9HD42|CHM1A_HUMAN,tr|A0A6Q8PHU0|A0A6Q8PHU0_HUMAN,tr|A0A6Q8PF35|A0A6Q8PF35_HUMAN,tr|A0A6Q8PG85|A0A6Q8PG85_HUMAN,tr|F8VUA2|F8VUA2_HUMAN,tr|F5H875|F5H875_HUMAN,tr|F8VVT7|F8VVT7_HUMAN,tr|A0A6Q8PFX8|A0A6Q8PFX8_HUMAN" 8 1013.5307 2.08 27743 11136 2 1013.529043 507.7726 Charged multivesicular body protein 1a OS=Homo sapiens OX=9606 GN=CHMP1A PE=1 SV=1 5.88 2351.6 - 1.09E+06 - - - -1.6171 - 1.312 0.007 - 174 1 2 0 -0.0016 9 0 0 0 4.04E+07 1.94E+07 - - - -0.1222 0.9986 221125_WJC_METTL3_EV_vs_WT_F03.11141.11141.2 0.0267 13/18 K.ALTSELANAR[166.11].D sp|P26038|MOES_HUMAN 1 1054.5646 3.29 27746 11141 2 1054.561742 528.2896 Moesin OS=Homo sapiens OX=9606 GN=MSN PE=1 SV=3 6.05 2352.3 - 2.40E+06 - - - -2.7509 - 2.211 0.276 - 587.7 1 2 0 -0.0029 10 0 0 0 2.42E+08 7.37E+07 - - - 3.2934 0.9996 221125_WJC_METTL3_EV_vs_WT_F03.11145.11145.2 0.00582 16-Oct K.FADIGNTVK[136.11].K "sp|P11172|UMPS_HUMAN,tr|E9PFD2|E9PFD2_HUMAN" 2 971.5167 2.96 27748 11145 2 971.51561 486.7656 Uridine 5'-monophosphate synthase OS=Homo sapiens OX=9606 GN=UMPS PE=1 SV=1 5.84 2352.7 - 1.27E+06 - - - -1.1693 - 1.859 0.382 - 216.7 1 2 0 -0.0011 9 0 0 0 1.28E+08 4.31E+07 - - - 3.6559 0.9724 221125_WJC_METTL3_EV_vs_WT_F03.11147.11147.2 0.298 16-Sep R.LLIYKVSNR.F sp|A0A075B6R9|KVD24_HUMAN 1 1104.6655 999 27749 11147 2 1104.661148 553.34 Probable non-functional immunoglobulin kappa variable 2D-24 OS=Homo sapiens OX=9606 GN=IGKV2D-24 PE=1 SV=1 9.99 2352.9 - 4.34E+06 - - - -3.9659 - 1.948 0.365 - 298.5 1 2 1 -0.0044 9 0 0 0 4.88E+08 0.00E+00 - - - 3.6646 0.9748 221125_WJC_METTL3_EV_vs_WT_F03.11150.11150.2 0.00198 22-Nov R.LLEGEDAHLSSS.Q sp|P02533|K1C14_HUMAN 1 1256.5885 - 27752 11150 2 1256.586382 629.3015 "Keratin, type I cytoskeletal 14 OS=Homo sapiens OX=9606 GN=KRT14 PE=1 SV=4" 4.13 2353.1 - 4.88E+06 - - - -1.6545 - 1.689 0.456 - 214.5 1 1 0 -0.0021 12 0 0 0 - - - - - 3.7875 0.9995 221125_WJC_METTL3_EV_vs_WT_F03.11151.11151.2 0.000345 16-Oct R.NAGYAVSLR.V "sp|P57105|SYJ2B_HUMAN,tr|A0A087X1F5|A0A087X1F5_HUMAN,tr|A0A087WYV9|A0A087WYV9_HUMAN" 3 949.4981 1.19 27753 11151 2 949.496166 475.7563 Synaptojanin-2-binding protein OS=Homo sapiens OX=9606 GN=SYNJ2BP PE=1 SV=2 8.75 2353.2 - 2.90E+06 - - - -2.0685 - 1.766 0.451 - 425.8 1 2 0 -0.002 9 0 0 0 1.47E+08 1.24E+08 - - - 4.0168 0.9999 221125_WJC_METTL3_EV_vs_WT_F03.11152.11152.2 0.00297 15/24 K.TVIVTGANTGIGK[136.11].Q "sp|Q8NBN7|RDH13_HUMAN,tr|G8JLA1|G8JLA1_HUMAN" 2 1237.7122 0.78 27754 11152 2 1237.71157 619.8634 Retinol dehydrogenase 13 OS=Homo sapiens OX=9606 GN=RDH13 PE=1 SV=2 8.41 2353.3 - 1.70E+06 - - - -0.4702 - 2.646 0.429 - 671.3 1 2 0 -0.0006 13 0 0 0 3.23E+07 4.15E+07 - - - 4.7068 0.9998 221125_WJC_METTL3_EV_vs_WT_F03.11155.11155.2 0.000102 16-Nov R.QAVDVSPLR[166.11].R "sp|P46782|RS5_HUMAN,tr|M0QZN2|M0QZN2_HUMAN,tr|M0R0F0|M0R0F0_HUMAN,tr|M0R0R2|M0R0R2_HUMAN" 4 993.5483 0.95 27755 11155 2 993.548616 497.7814 40S ribosomal protein S5 OS=Homo sapiens OX=9606 GN=RPS5 PE=1 SV=4 5.84 2353.7 - 2.38E+06 - - - 0.3543 - 2.291 0.398 - 510.6 1 2 0 0.0004 9 0 0 0 2.55E+09 2.67E+09 - - - 4.3788 0.9999 221125_WJC_METTL3_EV_vs_WT_F03.11157.11157.2 0.00434 15/24 K.TVIVTGANTGIGK.Q "sp|Q8NBN7|RDH13_HUMAN,tr|G8JLA1|G8JLA1_HUMAN" 2 1229.698 0.78 27757 11157 2 1229.697819 615.8563 Retinol dehydrogenase 13 OS=Homo sapiens OX=9606 GN=RDH13 PE=1 SV=2 8.41 2354 - 2.01E+06 - - - -0.1082 - 2.481 0.435 - 692.8 1 2 0 -0.0001 13 0 0 0 3.23E+07 4.15E+07 - - - 4.586 0.9908 221125_WJC_METTL3_EV_vs_WT_F03.11162.11162.2 0.137 14-Aug R.ALYEQEIR.D sp|P07196|NFL_HUMAN 1 1020.524 0.35 27759 11162 2 1020.52011 511.2693 Neurofilament light polypeptide OS=Homo sapiens OX=9606 GN=NEFL PE=1 SV=3 4.53 2354.6 - 2.53E+06 - - - -3.8216 - 1.741 0.209 - 291 1 2 0 -0.0039 8 0 0 0 9.68E+07 2.79E+08 - - - 2.2557 0.9933 221125_WJC_METTL3_EV_vs_WT_F03.11164.11164.2 0.401 18-Dec R.IAEVDASVVR[166.11].E sp|P31930|QCR1_HUMAN 1 1067.585 0.46 27761 11164 2 1067.586183 534.7998 "Cytochrome b-c1 complex subunit 1, mitochondrial OS=Homo sapiens OX=9606 GN=UQCRC1 PE=1 SV=3" 4.37 2354.8 - 6.37E+06 - - - 1.0669 - 2.089 0.002 - 519.1 1 2 0 0.0011 10 0 0 0 1.16E+08 2.55E+08 - - - 1.1117 0.9998 221125_WJC_METTL3_EV_vs_WT_F03.11168.11168.2 0.000237 14-Oct K.YLQQAFEK.S sp|Q9Y2X9|ZN281_HUMAN 1 1025.5182 0.92 27762 11168 2 1025.51739 513.7664 Zinc finger protein 281 OS=Homo sapiens OX=9606 GN=ZNF281 PE=1 SV=1 6 2355.4 - 3.96E+06 - - - -0.7859 - 1.904 0.412 - 240.5 1 2 0 -0.0008 8 0 0 0 1.50E+08 1.64E+08 - - - 4.0259 0.9996 221125_WJC_METTL3_EV_vs_WT_F03.11178.11178.2 0.000715 13/22 K.VPLEVQEADEAK[136.11].L "sp|P26640|SYVC_HUMAN,tr|A0A140T936|A0A140T936_HUMAN" 2 1334.6809 0.62 27768 11178 2 1334.677818 668.3477 Valine--tRNA ligase OS=Homo sapiens OX=9606 GN=VARS1 PE=1 SV=4 4 2356.4 - 1.72E+06 - - - -2.3174 - 2.621 0.428 - 637.5 1 2 0 -0.0031 12 0 0 0 2.75E+07 4.46E+07 - - - 4.7365 0.9284 221125_WJC_METTL3_EV_vs_WT_F03.11186.11186.2 2.13 12-Jun R.WFSNPSR[166.11].S "sp|Q9NRA8|4ET_HUMAN,tr|B1AKL4|B1AKL4_HUMAN" 2 902.4274 1.56 27771 11186 2 902.425006 452.221 Eukaryotic translation initiation factor 4E transporter OS=Homo sapiens OX=9606 GN=EIF4ENIF1 PE=1 SV=2 9.75 2357.5 - 6.35E+06 - - - -2.6761 - 1.22 0.06 - 191.9 1 2 0 -0.0024 7 0 0 0 4.36E+08 2.79E+08 - - - 0.1135 0.9961 221125_WJC_METTL3_EV_vs_WT_F03.11189.11189.2 0.0181 14-Jun R.ELYQQLQR.G "sp|Q15149|PLEC_HUMAN,tr|H0YDN1|H0YDN1_HUMAN" 2 1076.5615 1.61 27772 11189 2 1076.560299 539.288 Plectin OS=Homo sapiens OX=9606 GN=PLEC PE=1 SV=3 6.1 2357.9 - 1.99E+06 - - - -1.0766 - 1.309 0.216 - 121 1 2 0 -0.0012 8 0 0 0 6.59E+07 4.10E+07 - - - 1.4481 1 221125_WJC_METTL3_EV_vs_WT_F03.11193.11193.2 2.16E-09 15/22 Y.AAMLAAQDVAQR.C "sp|P62263|RS14_HUMAN,tr|A0A2R8Y811|A0A2R8Y811_HUMAN,tr|E5RH77|E5RH77_HUMAN" 3 1243.6343 0.78 27774 11193 2 1243.632356 622.8244 40S ribosomal protein S14 OS=Homo sapiens OX=9606 GN=RPS14 PE=1 SV=3 5.88 2358.3 - 1.29E+06 - - - -1.568 - 3.162 0.558 - 996.8 1 1 0 -0.0019 12 0 0 0 7.94E+07 1.02E+08 - - - 6.1908 0.9997 221125_WJC_METTL3_EV_vs_WT_F03.11196.11196.2 0.0955 18-Oct R.VLELNASDER[166.11].G "sp|P35249|RFC4_HUMAN,tr|C9JXZ7|C9JXZ7_HUMAN,tr|C9J8M3|C9J8M3_HUMAN,tr|C9JZI1|C9JZI1_HUMAN" 4 1154.5807 1.04 27775 11196 2 1154.580015 578.2976 Replication factor C subunit 4 OS=Homo sapiens OX=9606 GN=RFC4 PE=1 SV=2 4.14 2358.7 - 1.74E+06 - - - -0.582 - 2.168 0.323 - 355.5 1 2 0 -0.0007 10 0 0 0 6.23E+07 5.98E+07 - - - 3.5864 0.9994 221125_WJC_METTL3_EV_vs_WT_F03.11203.11203.2 0.000183 14-Jul R.GC[160.03]AVVEFK.M "sp|P52272|HNRPM_HUMAN,tr|M0R019|M0R019_HUMAN,tr|M0R0N3|M0R0N3_HUMAN,tr|M0QYL3|M0QYL3_HUMAN,tr|M0R2T0|M0R2T0_HUMAN" 5 908.4426 1.68 27777 11203 2 908.441725 455.2286 Heterogeneous nuclear ribonucleoprotein M OS=Homo sapiens OX=9606 GN=HNRNPM PE=1 SV=3 5.99 2359.6 - 6.91E+06 - - - -0.9511 - 1.61 0.347 - 245.6 1 2 0 -0.0009 8 0 0 0 1.70E+09 1.02E+09 - - - 3.04 0.9979 221125_WJC_METTL3_EV_vs_WT_F03.11207.11207.2 0.0664 14-Oct R.YQEQLLDR.T "sp|Q96FZ7|CHMP6_HUMAN,tr|I3L4A1|I3L4A1_HUMAN,tr|I3L4G8|I3L4G8_HUMAN" 3 1063.5298 1.34 27779 11207 2 1063.525674 532.7722 Charged multivesicular body protein 6 OS=Homo sapiens OX=9606 GN=CHMP6 PE=1 SV=3 4.37 2360.1 - 2.10E+06 - - - -3.9021 - 1.827 0.405 - 344.8 1 2 0 -0.0041 8 0 0 0 3.85E+08 2.88E+08 - - - 3.8487 0.998 221125_WJC_METTL3_EV_vs_WT_F03.11209.11209.2 1.90E-07 22-Dec R.AQPSASLGVGYR[166.11].T sp|Q96PK6|RBM14_HUMAN 1 1214.6283 2.03 27780 11209 2 1214.622042 608.3214 RNA-binding protein 14 OS=Homo sapiens OX=9606 GN=RBM14 PE=1 SV=2 8.79 2360.3 - 4.98E+06 - - - -5.1571 - 2.365 0.56 - 509.2 1 2 0 -0.0063 12 0 0 0 9.16E+08 4.51E+08 - - - 5.44 0.9999 221125_WJC_METTL3_EV_vs_WT_F03.11215.11215.2 9.67E-09 22-Nov R.AQPSASLGVGYR.T sp|Q96PK6|RBM14_HUMAN 1 1204.62 2.07 27783 11215 2 1204.618648 603.3173 RNA-binding protein 14 OS=Homo sapiens OX=9606 GN=RBM14 PE=1 SV=2 8.79 2361 - 9.34E+06 - - - -1.1522 - 2.27 0.598 - 412.7 1 2 0 -0.0014 12 0 0 0 4.01E+08 1.94E+08 - - - 5.6144 0.8907 221125_WJC_METTL3_EV_vs_WT_F03.11217.11217.2 0.144 14-Jul R.YPDGIISK[136.11].P sp|Q86U44|MTA70_HUMAN 1 899.4844 0.04 27784 11217 2 899.483298 450.7495 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 5.83 2361.2 - 6.72E+06 - - - -1.2062 - 1.5 0.235 - 139.3 1 1 0 -0.0011 8 0 0 0 1.15E+07 3.05E+08 - - - 1.9992 0.9986 221125_WJC_METTL3_EV_vs_WT_F03.11219.11219.2 0.00652 12-Sep K.LHDAFFK.W "sp|Q13435|SF3B2_HUMAN,tr|E9PPJ0|E9PPJ0_HUMAN" 2 876.4494 2.01 27785 11219 2 876.447533 439.232 Splicing factor 3B subunit 2 OS=Homo sapiens OX=9606 GN=SF3B2 PE=1 SV=2 6.74 2361.4 - 2.54E+06 - - - -2.1165 - 1.54 0.328 - 340.5 1 2 0 -0.0019 7 0 0 0 2.56E+08 1.28E+08 - - - 2.8312 0.9999 221125_WJC_METTL3_EV_vs_WT_F03.11221.11221.2 8.32E-05 14/20 R.GALTGGYYDTR[166.11].K sp|Q9UQE7|SMC3_HUMAN 1 1182.5545 0.81 27786 11221 2 1182.555187 592.2845 Structural maintenance of chromosomes protein 3 OS=Homo sapiens OX=9606 GN=SMC3 PE=1 SV=2 5.83 2361.6 - 1.52E+06 - - - 0.6046 - 2.608 0.458 - 617.4 1 2 0 0.0007 11 0 0 0 8.44E+07 1.04E+08 - - - 5.0168 0.9984 221125_WJC_METTL3_EV_vs_WT_F03.11223.11223.2 0.0127 14-Aug R.GC[160.03]AVVEFK[136.11].M "sp|P52272|HNRPM_HUMAN,tr|M0R019|M0R019_HUMAN,tr|M0R0N3|M0R0N3_HUMAN,tr|M0QYL3|M0QYL3_HUMAN,tr|M0R2T0|M0R2T0_HUMAN" 5 916.4568 1.68 27787 11223 2 916.453915 459.2357 Heterogeneous nuclear ribonucleoprotein M OS=Homo sapiens OX=9606 GN=HNRNPM PE=1 SV=3 5.99 2361.8 - 1.83E+07 - - - -3.136 - 1.757 0.375 - 346.4 1 2 0 -0.0029 8 0 0 0 1.70E+09 1.02E+09 - - - 3.5097 0.9997 221125_WJC_METTL3_EV_vs_WT_F03.11228.11228.2 0.00041 12-Sep K.LHDAFFK[136.11].W "sp|Q13435|SF3B2_HUMAN,tr|E9PPJ0|E9PPJ0_HUMAN" 2 884.4636 2.14 27789 11228 2 884.463913 443.2391 Splicing factor 3B subunit 2 OS=Homo sapiens OX=9606 GN=SF3B2 PE=1 SV=2 6.74 2362.4 - 3.32E+06 - - - 0.3675 - 1.796 0.365 - 391.2 1 2 0 0.0003 7 0 0 0 2.54E+08 1.19E+08 - - - 3.5922 0.9614 221125_WJC_METTL3_EV_vs_WT_F03.11232.11232.2 3.61 14-Jul K.GITLSVRP.- tr|A0A075B6Z2|A0A075B6Z2_HUMAN 1 841.5022 1314987.32 27792 11232 2 841.501293 421.7584 T cell receptor alpha joining 56 (Fragment) OS=Homo sapiens OX=9606 GN=TRAJ56 PE=4 SV=1 9.75 2362.9 - 8.09E+09 - - - -1.0208 - 1.292 0.023 - 185.2 2 2 0 -0.0009 8 0 0 0 7.30E+11 5.55E+05 - - - -0.1512 0.9985 221125_WJC_METTL3_EV_vs_WT_F03.11233.11233.2 0.000284 18-Dec K.FADLSEAANR.N "sp|P08670|VIME_HUMAN,tr|B0YJC5|B0YJC5_HUMAN,tr|B0YJC4|B0YJC4_HUMAN" 3 1092.52 1.94 27793 11233 2 1092.515461 547.2673 Vimentin OS=Homo sapiens OX=9606 GN=VIM PE=1 SV=4 4.37 2362.9 - 3.90E+06 - - - -4.1427 - 2.085 0.463 - 485.4 1 2 0 -0.0045 10 0 0 0 1.68E+10 8.65E+09 - - - 4.5103 0.9989 221125_WJC_METTL3_EV_vs_WT_F03.11236.11236.2 0.0365 18-Nov K.FADLSEAANR[166.11].N "sp|P08670|VIME_HUMAN,tr|B0YJC5|B0YJC5_HUMAN,tr|B0YJC4|B0YJC4_HUMAN" 3 1102.5283 1.94 27794 11236 2 1102.524342 552.2714 Vimentin OS=Homo sapiens OX=9606 GN=VIM PE=1 SV=4 4.37 2363.3 - 6.09E+06 - - - -3.5509 - 2.011 0.453 - 403.8 1 2 0 -0.0039 10 0 0 0 1.68E+10 8.65E+09 - - - 4.3357 0.9615 221125_WJC_METTL3_EV_vs_WT_F03.11238.11238.2 0.0861 14-Sep K.ALVAYYQK[136.11].Y "sp|P62249|RS16_HUMAN,tr|M0R210|M0R210_HUMAN,tr|M0R3H0|M0R3H0_HUMAN,tr|M0QX76|M0QX76_HUMAN,tr|M0R1M5|M0R1M5_HUMAN" 5 962.5317 0.5 27796 11238 2 962.525455 482.2731 40S ribosomal protein S16 OS=Homo sapiens OX=9606 GN=RPS16 PE=1 SV=2 8.54 2363.5 - 3.82E+06 - - - -6.4549 - 1.724 0.263 - 316 1 2 0 -0.0062 8 0 0 0 9.98E+07 1.98E+08 - - - 2.6242 0.9997 221125_WJC_METTL3_EV_vs_WT_F03.11242.11242.2 2.78E-06 20-Dec K.EAAENSLVAYK.A "sp|P62258|1433E_HUMAN,tr|K7EM20|K7EM20_HUMAN" 2 1193.5928 1.07 27798 11242 2 1193.595775 597.8037 14-3-3 protein epsilon OS=Homo sapiens OX=9606 GN=YWHAE PE=1 SV=1 4.53 2364 - 3.54E+06 - - - 2.4774 - 2.332 0.537 - 599.3 1 2 0 0.003 11 0 0 0 5.41E+08 5.07E+08 - - - 5.2969 0.9975 221125_WJC_METTL3_EV_vs_WT_F03.11245.11245.2 0.672 16-Jul R.LEQDEYALR[166.11].S "sp|P55084|ECHB_HUMAN,tr|F5GZQ3|F5GZQ3_HUMAN" 2 1145.5592 0.65 27799 11245 2 1145.558199 573.7869 "Trifunctional enzyme subunit beta, mitochondrial OS=Homo sapiens OX=9606 GN=HADHB PE=1 SV=3" 4.14 2364.4 - 4.43E+06 - - - -0.8939 - 1.521 0.201 - 61 1 2 0 -0.001 9 0 0 0 6.13E+08 9.36E+08 - - - 1.7385 0.9995 221125_WJC_METTL3_EV_vs_WT_F03.11247.11247.2 1.40E-05 16-Sep R.LEQDEYALR.S "sp|P55084|ECHB_HUMAN,tr|F5GZQ3|F5GZQ3_HUMAN" 2 1135.551 0.66 27800 11247 2 1135.553698 568.7828 "Trifunctional enzyme subunit beta, mitochondrial OS=Homo sapiens OX=9606 GN=HADHB PE=1 SV=3" 4.14 2364.6 - 4.63E+06 - - - 2.4173 - 1.938 0.461 - 327.6 1 2 0 0.0027 9 0 0 0 6.13E+08 9.28E+08 - - - 4.3593 0.9997 221125_WJC_METTL3_EV_vs_WT_F03.11248.11248.2 0.000212 13/20 R.VLVDQTTGLSR.G sp|Q15717|ELAV1_HUMAN 1 1187.651 1.29 27801 11248 2 1187.648047 594.8328 ELAV-like protein 1 OS=Homo sapiens OX=9606 GN=ELAVL1 PE=1 SV=2 5.81 2364.7 - 2.43E+06 - - - -2.4873 - 2.53 0.47 - 623.9 1 2 0 -0.003 11 0 0 0 2.00E+09 1.55E+09 - - - 5.0225 0.9726 221125_WJC_METTL3_EV_vs_WT_F03.11255.11255.2 0.038 14-Jul R.DVAYQYVK[136.11].K "sp|Q04837|SSBP_HUMAN,tr|C9K0U8|C9K0U8_HUMAN,tr|A0A0G2JLD8|A0A0G2JLD8_HUMAN,tr|E7EUY5|E7EUY5_HUMAN" 4 992.5058 1.08 27805 11255 2 992.502713 497.2602 "Single-stranded DNA-binding protein, mitochondrial OS=Homo sapiens OX=9606 GN=SSBP1 PE=1 SV=1" 5.83 2365.5 - 1.51E+07 - - - -3.1577 - 1.095 0.232 - 122.9 1 2 0 -0.0031 8 0 0 0 9.28E+08 8.62E+08 - - - 1.0273 0.9999 221125_WJC_METTL3_EV_vs_WT_F03.11258.11258.2 4.26E-07 20-Dec K.EAAENSLVAYK[136.11].A "sp|P62258|1433E_HUMAN,tr|K7EM20|K7EM20_HUMAN" 2 1201.607 1.09 27806 11258 2 1201.605402 601.8108 14-3-3 protein epsilon OS=Homo sapiens OX=9606 GN=YWHAE PE=1 SV=1 4.53 2365.9 - 8.05E+06 - - - -1.3449 - 2.508 0.538 - 655.2 1 2 0 -0.0016 11 0 0 0 5.41E+08 4.98E+08 - - - 5.5016 0.9998 221125_WJC_METTL3_EV_vs_WT_F03.11259.11259.2 0.000692 18-Sep K.VLPIQDNVSK[136.11].D "sp|Q9NRY5|F1142_HUMAN,tr|E5RHI8|E5RHI8_HUMAN,tr|E5RHP2|E5RHP2_HUMAN,tr|E5RGF9|E5RGF9_HUMAN,tr|E5RFK2|E5RFK2_HUMAN,tr|E5RK42|E5RK42_HUMAN" 6 1119.6379 1.2 27807 11259 2 1119.637889 560.8262 Protein FAM114A2 OS=Homo sapiens OX=9606 GN=FAM114A2 PE=1 SV=4 5.81 2366 - 4.63E+06 - - - -0.0313 - 1.817 0.475 - 255.8 1 2 0 0 10 0 0 0 6.63E+08 5.54E+08 - - - 4.2163 0.9995 221125_WJC_METTL3_EV_vs_WT_F03.11262.11262.2 9.73E-06 20-Nov R.VLVDQTTGLSR[166.11].G sp|Q15717|ELAV1_HUMAN 1 1197.6593 1.29 27808 11262 2 1197.655999 599.8369 ELAV-like protein 1 OS=Homo sapiens OX=9606 GN=ELAVL1 PE=1 SV=2 5.81 2366.4 - 1.24E+07 - - - -2.732 - 2.351 0.459 - 400 1 2 0 -0.0033 11 0 0 0 2.00E+09 1.55E+09 - - - 4.7427 0.9989 221125_WJC_METTL3_EV_vs_WT_F03.11266.11266.2 0.0012 14-Aug R.YQEQLLDR[166.11].T "sp|Q96FZ7|CHMP6_HUMAN,tr|I3L4A1|I3L4A1_HUMAN,tr|I3L4G8|I3L4G8_HUMAN" 3 1073.5381 1.34 27810 11266 2 1073.535265 537.7763 Charged multivesicular body protein 6 OS=Homo sapiens OX=9606 GN=CHMP6 PE=1 SV=3 4.37 2366.8 - 5.42E+06 - - - -2.6352 - 1.606 0.414 - 197.4 1 2 0 -0.0028 8 0 0 0 3.85E+08 2.88E+08 - - - 3.5267 0.9961 221125_WJC_METTL3_EV_vs_WT_F03.11269.11269.2 0.016 18-Aug K.VLPIQDNVSK.D "sp|Q9NRY5|F1142_HUMAN,tr|E5RHI8|E5RHI8_HUMAN,tr|E5RHP2|E5RHP2_HUMAN,tr|E5RGF9|E5RGF9_HUMAN,tr|E5RFK2|E5RFK2_HUMAN,tr|E5RK42|E5RK42_HUMAN" 6 1111.6237 1.2 27811 11269 2 1111.619956 556.8191 Protein FAM114A2 OS=Homo sapiens OX=9606 GN=FAM114A2 PE=1 SV=4 5.81 2367.2 - 5.58E+06 - - - -3.3896 - 1.33 0.395 - 214.1 1 2 0 -0.0038 10 0 0 0 6.63E+08 5.54E+08 - - - 2.7533 0.9892 221125_WJC_METTL3_EV_vs_WT_F03.11271.11271.2 0.614 14-Aug K.ALVAYYQK.Y "sp|P62249|RS16_HUMAN,tr|M0R210|M0R210_HUMAN,tr|M0R3H0|M0R3H0_HUMAN,tr|M0QX76|M0QX76_HUMAN,tr|M0R1M5|M0R1M5_HUMAN" 5 954.5175 0.43 27812 11271 2 954.515183 478.266 40S ribosomal protein S16 OS=Homo sapiens OX=9606 GN=RPS16 PE=1 SV=2 8.54 2367.4 - 2.42E+06 - - - -2.3939 - 1.588 0.117 - 228 1 2 0 -0.0023 8 0 0 0 7.55E+07 1.75E+08 - - - 1.2992 1 221125_WJC_METTL3_EV_vs_WT_F03.11276.11276.2 1.43E-07 18-Nov P.YGTLTDDEMR[166.11].R sp|Q86U44|MTA70_HUMAN 1 1209.5211 0.001 27814 11276 2 1209.515955 605.7678 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 4.03 2368 - 3.17E+06 - - - -4.2728 - 2.505 0.637 - 519 1 1 0 -0.0052 10 0 0 0 0.00E+00 1.83E+08 - - - 6.3075 0.7879 221125_WJC_METTL3_EV_vs_WT_F03.11282.11282.2 0.613 12-Aug N.LNTLIQR[166.11].S "sp|P20036|DPA1_HUMAN,sp|Q00839|HNRPU_HUMAN,sp|Q8IUG5|MY18B_HUMAN,tr|A0A140T914|A0A140T914_HUMAN,tr|A0A1W2PQL0|A0A1W2PQL0_HUMAN,tr|A0A1W2PPE9|A0A1W2PPE9_HUMAN,tr|A0A1W2PPL4|A0A1W2PPL4_HUMAN,tr|A0A1W2PQ74|A0A1W2PQ74_HUMAN,tr|F5H6I8|F5H6I8_HUMAN,tr|A0A140T9R4|A0A140T9R4_HUMAN,tr|Q5RI18|Q5RI18_HUMAN,tr|A0A140T9D6|A0A140T9D6_HUMAN,tr|A0A1W2PP35|A0A1W2PP35_HUMAN,tr|A0A1W2PPS1|A0A1W2PPS1_HUMAN,tr|A0A140T9Y9|A0A140T9Y9_HUMAN,tr|A0A1W2PRZ7|A0A1W2PRZ7_HUMAN,tr|A0A140T9H1|A0A140T9H1_HUMAN,tr|A0A1W2PPH7|A0A1W2PPH7_HUMAN,tr|A0A1W2PQD4|A0A1W2PQD4_HUMAN,tr|A0A140T9U4|A0A140T9U4_HUMAN,tr|A0A1W2PP34|A0A1W2PP34_HUMAN,tr|A0A1X7SBS1|A0A1X7SBS1_HUMAN,tr|A0A140T9F8|A0A140T9F8_HUMAN,tr|J3KQ99|J3KQ99_HUMAN" 24 866.5213 0.97 27815 11282 2 866.519388 434.2679 "HLA class II histocompatibility antigen, DP alpha 1 chain OS=Homo sapiens OX=9606 GN=HLA-DPA1 PE=1 SV=1" 9.75 2368.9 - 1.22E+07 - - - -2.2308 - 1.772 0.141 - 223.4 1 1 0 -0.0019 7 0 0 0 5.16E+08 5.30E+08 - - - 1.8946 0.9924 221125_WJC_METTL3_EV_vs_WT_F03.11283.11283.2 0.105 16-Sep K.AVDSQILPK.L sp|Q02878|RL6_HUMAN 1 969.5495 1.1 27816 11283 2 969.546178 485.782 60S ribosomal protein L6 OS=Homo sapiens OX=9606 GN=RPL6 PE=1 SV=3 5.88 2369 - 1.95E+06 - - - -3.4222 - 1.552 0.252 - 216.3 1 2 0 -0.0033 9 0 0 0 2.28E+08 2.08E+08 - - - 2.1729 0.9987 221125_WJC_METTL3_EV_vs_WT_F03.11284.11284.2 0.235 12-Sep K.SDIVQLR.G "sp|Q00341|VIGLN_HUMAN,tr|A0A024R4E5|A0A024R4E5_HUMAN,tr|H7BZC3|H7BZC3_HUMAN,tr|H0Y394|H0Y394_HUMAN" 4 829.4658 1.32 27817 11284 2 829.465551 415.7402 Vigilin OS=Homo sapiens OX=9606 GN=HDLBP PE=1 SV=2 5.55 2369.1 - 3.13E+06 - - - -0.2604 - 1.989 0.121 - 353.5 1 2 0 -0.0002 7 0 0 0 1.00E+08 7.56E+07 - - - 2.1134 0.9895 221125_WJC_METTL3_EV_vs_WT_F03.11289.11289.2 0.00049 16-Aug K.EGVLYVGSK[136.11].T "sp|Q16143|SYUB_HUMAN,sp|P37840|SYUA_HUMAN,tr|A0A669KB41|A0A669KB41_HUMAN,tr|D6RA31|D6RA31_HUMAN,tr|A0A669KBH5|A0A669KBH5_HUMAN,tr|E7EPV7|E7EPV7_HUMAN" 6 958.5215 1.46 27819 11289 2 958.515632 480.268 Beta-synuclein OS=Homo sapiens OX=9606 GN=SNCB PE=1 SV=1 6.1 2369.7 - 4.46E+06 - - - -6.1188 - 1.985 0.374 - 165.5 1 2 0 -0.0059 9 0 0 0 3.44E+09 2.35E+09 - - - 3.7851 0.9998 221125_WJC_METTL3_EV_vs_WT_F03.11299.11299.2 1.63E-05 15/24 R.ALGQNPTNAEVLK[136.11].V "sp|P14649|MYL6B_HUMAN,sp|P60660|MYL6_HUMAN,tr|F8W1R7|F8W1R7_HUMAN,tr|G3V1V0|G3V1V0_HUMAN,tr|B7Z6Z4|B7Z6Z4_HUMAN,tr|G8JLA2|G8JLA2_HUMAN,tr|F8W1I5|F8W1I5_HUMAN,tr|J3KND3|J3KND3_HUMAN,tr|F8VPF3|F8VPF3_HUMAN" 9 1361.7394 1.37 27824 11299 2 1361.742181 681.877 Myosin light chain 6B OS=Homo sapiens OX=9606 GN=MYL6B PE=1 SV=1 6.05 2370.9 - 1.96E+06 - - - 2.0209 - 2.611 0.504 - 299.5 1 2 0 0.0028 13 0 0 0 1.13E+09 8.23E+08 - - - 5.2259 0.9999 221125_WJC_METTL3_EV_vs_WT_F03.11301.11301.2 0.00117 20-Oct K.LVIVGDGAC[160.03]GK.T "sp|P61586|RHOA_HUMAN,sp|P08134|RHOC_HUMAN,tr|E9PLA2|E9PLA2_HUMAN,tr|U3KQA9|U3KQA9_HUMAN,tr|U3KQV3|U3KQV3_HUMAN,tr|E9PQH6|E9PQH6_HUMAN,tr|Q5JR06|Q5JR06_HUMAN,tr|C9JNR4|C9JNR4_HUMAN,tr|A0A7I2V3G1|A0A7I2V3G1_HUMAN,tr|Q5JR08|Q5JR08_HUMAN,tr|C9JX21|C9JX21_HUMAN,tr|Q5JR05|Q5JR05_HUMAN,tr|E9PN11|E9PN11_HUMAN,tr|A0A7I2V5E6|A0A7I2V5E6_HUMAN,tr|C9JRM1|C9JRM1_HUMAN,tr|Q5JR07|Q5JR07_HUMAN,tr|A0A7I2YQV1|A0A7I2YQV1_HUMAN" 17 1087.5696 1.06 27825 11301 2 1087.569838 544.7921 Transforming protein RhoA OS=Homo sapiens OX=9606 GN=RHOA PE=1 SV=1 5.83 2371.2 - 2.16E+06 - - - 0.2372 - 1.949 0.53 - 267.6 1 2 0 0.0003 11 0 0 0 1.67E+08 1.58E+08 - - - 4.7607 0.9998 221125_WJC_METTL3_EV_vs_WT_F03.11303.11303.2 9.29E-05 15/24 R.ALGQNPTNAEVLK.V "sp|P14649|MYL6B_HUMAN,sp|P60660|MYL6_HUMAN,tr|F8W1R7|F8W1R7_HUMAN,tr|G3V1V0|G3V1V0_HUMAN,tr|B7Z6Z4|B7Z6Z4_HUMAN,tr|G8JLA2|G8JLA2_HUMAN,tr|F8W1I5|F8W1I5_HUMAN,tr|J3KND3|J3KND3_HUMAN,tr|F8VPF3|F8VPF3_HUMAN" 9 1353.7252 1.37 27827 11303 2 1353.72274 677.8699 Myosin light chain 6B OS=Homo sapiens OX=9606 GN=MYL6B PE=1 SV=1 6.05 2371.4 - 3.29E+06 - - - -1.8386 - 2.741 0.517 - 770.4 1 2 0 -0.0025 13 0 0 0 1.13E+09 8.23E+08 - - - 5.4467 0.8776 221125_WJC_METTL3_EV_vs_WT_F03.11309.11309.2 0.133 14-Jul R.GAIPSYMK[136.11].A sp|Q15208|STK38_HUMAN 1 873.451 3.77 27829 11309 2 873.445724 437.7328 Serine\threonine-protein kinase 38 OS=Homo sapiens OX=9606 GN=STK38 PE=1 SV=1 8.59 2372.3 - 2.43E+06 - - - -6.0118 - 1.291 0.209 - 98.9 1 2 0 -0.0053 8 0 0 0 5.82E+08 1.54E+08 - - - 1.3534 0.997 221125_WJC_METTL3_EV_vs_WT_F03.11312.11312.2 0.118 16-Aug K.AVDSQILPK[136.11].L sp|Q02878|RL6_HUMAN 1 977.5637 1.11 27830 11312 2 977.561794 489.7891 60S ribosomal protein L6 OS=Homo sapiens OX=9606 GN=RPL6 PE=1 SV=3 5.88 2372.7 - 2.88E+06 - - - -1.9457 - 1.367 0.285 - 180.3 1 2 0 -0.0019 9 0 0 0 2.20E+08 1.98E+08 - - - 2.0498 0.9986 221125_WJC_METTL3_EV_vs_WT_F03.11313.11313.2 0.00835 16-Sep R.ATSFATVVK.D "sp|Q9UPN3|MACF1_HUMAN,tr|H3BQK9|H3BQK9_HUMAN,tr|A0A7P0MQR8|A0A7P0MQR8_HUMAN,tr|E9PNZ4|E9PNZ4_HUMAN,tr|H0Y390|H0Y390_HUMAN,tr|H3BPE1|H3BPE1_HUMAN,tr|A0A590UJG2|A0A590UJG2_HUMAN" 7 922.5124 25.12 27831 11313 2 922.511884 462.2635 "Microtubule-actin cross-linking factor 1, isoforms 1\2\3\5 OS=Homo sapiens OX=9606 GN=MACF1 PE=1 SV=4" 8.8 2372.8 - 1.32E+06 - - - -0.5409 - 1.413 0.284 - 167.9 1 2 0 -0.0005 9 0 0 0 2.71E+08 1.08E+07 - - - 2.1386 0.998 221125_WJC_METTL3_EV_vs_WT_F03.11314.11314.2 0.271 14-Aug K.FLYDDNQR[166.11].V "sp|P11388|TOP2A_HUMAN,sp|Q02880|TOP2B_HUMAN,tr|E9PCY5|E9PCY5_HUMAN" 3 1079.4911 0.7 27832 11314 2 1079.490257 540.7528 DNA topoisomerase 2-alpha OS=Homo sapiens OX=9606 GN=TOP2A PE=1 SV=3 4.21 2372.9 - 1.31E+06 - - - -0.8208 - 1.439 0.236 - 217.4 1 2 0 -0.0009 8 0 0 0 2.99E+07 4.29E+07 - - - 1.8815 0.9995 221125_WJC_METTL3_EV_vs_WT_F03.11325.11325.2 0.0869 16-Nov R.YMEVSGNLR.D sp|Q12874|SF3A3_HUMAN 1 1067.507 2.58 27837 11325 2 1067.50518 534.7608 Splicing factor 3A subunit 3 OS=Homo sapiens OX=9606 GN=SF3A3 PE=1 SV=1 6 2374.3 - 2.73E+06 - - - -1.6862 - 1.896 0.371 - 463.6 1 2 0 -0.0018 9 0 0 0 4.05E+08 1.57E+08 - - - 3.6315 0.9996 221125_WJC_METTL3_EV_vs_WT_F03.11332.11332.3 0.00115 Oct-36 K.YEELQVTAGR.H "sp|P48668|K2C6C_HUMAN,sp|O95678|K2C75_HUMAN,sp|P02538|K2C6A_HUMAN" 3 1164.5775 999 27841 11332 3 1164.575262 389.1998 "Keratin, type II cytoskeletal 6C OS=Homo sapiens OX=9606 GN=KRT6C PE=1 SV=3" 4.53 2375 - 3.68E+06 - - - -1.9234 - 1.721 0.388 - 182.4 1 2 0 -0.0022 10 0 0 0 1.53E+08 0.00E+00 - - - 4.4507 0.7799 221125_WJC_METTL3_EV_vs_WT_F03.11333.11333.2 0.0666 14-Jul S.NVEEIVVK[136.11].N "sp|Q96KC2|ARL5B_HUMAN,sp|Q9H583|HEAT1_HUMAN,tr|Q5T3Q7|Q5T3Q7_HUMAN" 3 936.5371 0.9 27842 11333 2 936.53584 469.2758 ADP-ribosylation factor-like protein 5B OS=Homo sapiens OX=9606 GN=ARL5B PE=1 SV=1 4.53 2375.2 - 841381 - - - -1.3956 - 1.226 0.24 - 147.4 1 1 0 -0.0013 8 0 0 0 3.02E+07 3.36E+07 - - - 1.4278 0.9991 221125_WJC_METTL3_EV_vs_WT_F03.11335.11335.2 0.0308 16-Aug K.FMGTELNGK.T "sp|O43175|SERA_HUMAN,tr|A0A286YF78|A0A286YF78_HUMAN,tr|A0A2C9F2M7|A0A2C9F2M7_HUMAN,tr|A0A286YF22|A0A286YF22_HUMAN,tr|A0A286YFL2|A0A286YFL2_HUMAN,tr|A0A286YFA2|A0A286YFA2_HUMAN,tr|A0A286YFM8|A0A286YFM8_HUMAN,tr|A0A286YFE1|A0A286YFE1_HUMAN" 8 995.4746 1.36 27844 11335 2 995.474812 498.7446 D-3-phosphoglycerate dehydrogenase OS=Homo sapiens OX=9606 GN=PHGDH PE=1 SV=4 6 2375.4 - 1.90E+06 - - - 0.1959 - 1.321 0.358 - 153.5 1 2 0 0.0002 9 0 0 0 1.60E+08 1.18E+08 - - - 2.4905 0.7984 221125_WJC_METTL3_EV_vs_WT_F03.11337.11337.2 0.247 12-Jul K.KPELVIS.Y "sp|P78347|GTF2I_HUMAN,tr|A0A494C1K3|A0A494C1K3_HUMAN" 2 784.4695 1.15 27846 11337 2 784.467128 393.242 General transcription factor II-I OS=Homo sapiens OX=9606 GN=GTF2I PE=1 SV=2 6 2375.7 - 950662 - - - -2.9663 - 1.567 0.263 - 171.9 1 1 0 -0.0023 7 0 0 0 6.22E+07 5.40E+07 - - - 2.406 0.9861 221125_WJC_METTL3_EV_vs_WT_F03.11340.11340.2 0.209 14-Jul K.NIILEEGK.E "sp|P23528|COF1_HUMAN,tr|E9PP50|E9PP50_HUMAN,tr|G3V1A4|G3V1A4_HUMAN,tr|E9PQB7|E9PQB7_HUMAN,tr|E9PK25|E9PK25_HUMAN,tr|E9PLJ3|E9PLJ3_HUMAN,tr|E9PS23|E9PS23_HUMAN" 7 914.5073 1.87 27847 11340 2 914.504955 458.2609 Cofilin-1 OS=Homo sapiens OX=9606 GN=CFL1 PE=1 SV=3 4.53 2376.1 - 1.36E+07 - - - -2.5609 - 1.537 0.118 - 192.3 1 2 0 -0.0023 8 0 0 0 4.58E+08 2.45E+08 - - - 1.2082 0.9999 221125_WJC_METTL3_EV_vs_WT_F03.11341.11341.2 0.00587 16-Nov R.YMEVSGNLR[166.11].D sp|Q12874|SF3A3_HUMAN 1 1077.5152 3.77 27848 11341 2 1077.514106 539.7649 Splicing factor 3A subunit 3 OS=Homo sapiens OX=9606 GN=SF3A3 PE=1 SV=1 6 2376.2 - 2.99E+06 - - - -1.0617 - 2.068 0.514 - 465.3 1 2 0 -0.0011 9 0 0 0 3.79E+08 1.00E+08 - - - 4.9391 0.9992 221125_WJC_METTL3_EV_vs_WT_F03.11342.11342.2 0.00235 16-Oct K.FMGTELNGK[136.11].T "sp|O43175|SERA_HUMAN,tr|A0A286YF78|A0A286YF78_HUMAN,tr|A0A2C9F2M7|A0A2C9F2M7_HUMAN,tr|A0A286YF22|A0A286YF22_HUMAN,tr|A0A286YFL2|A0A286YFL2_HUMAN,tr|A0A286YFA2|A0A286YFA2_HUMAN,tr|A0A286YFM8|A0A286YFM8_HUMAN,tr|A0A286YFE1|A0A286YFE1_HUMAN" 8 1003.4888 1.36 27849 11342 2 1003.487756 502.7517 D-3-phosphoglycerate dehydrogenase OS=Homo sapiens OX=9606 GN=PHGDH PE=1 SV=4 6 2376.3 - 3.43E+06 - - - -1.0573 - 1.517 0.338 - 190 1 2 0 -0.0011 9 0 0 0 1.60E+08 1.18E+08 - - - 2.7428 0.998 221125_WJC_METTL3_EV_vs_WT_F03.11347.11347.2 17.3 14-Aug K.SISISVAR.G sp|P04264|K2C1_HUMAN 1 831.4814 2.71 27852 11347 2 831.481975 416.748 "Keratin, type II cytoskeletal 1 OS=Homo sapiens OX=9606 GN=KRT1 PE=1 SV=6" 9.47 2376.9 - 3.20E+06 - - - 0.6711 - 1.624 0.188 - 189.5 1 2 0 0.0006 8 0 0 0 2.34E+10 8.65E+09 - - - 1.8918 0.999 221125_WJC_METTL3_EV_vs_WT_F03.11348.11348.2 0.0045 14-Sep K.IWDVSSGK.C sp|P61964|WDR5_HUMAN 1 890.4498 1.62 27853 11348 2 890.447671 446.2322 WD repeat-containing protein 5 OS=Homo sapiens OX=9606 GN=WDR5 PE=1 SV=1 5.84 2376.9 - 2.85E+06 - - - -2.3707 - 1.682 0.374 - 255.7 1 2 0 -0.0021 8 0 0 0 8.44E+07 5.20E+07 - - - 3.3709 0.998 221125_WJC_METTL3_EV_vs_WT_F03.11354.11354.2 2.29E-05 18-Oct K.MIDMAEPAQR[166.11].K "sp|Q8TB72|PUM2_HUMAN,tr|A0A0C4DG68|A0A0C4DG68_HUMAN" 2 1170.5401 2.27 27857 11354 2 1170.535041 586.2773 Pumilio homolog 2 OS=Homo sapiens OX=9606 GN=PUM2 PE=1 SV=2 4.37 2377.6 - 2.67E+06 - - - -4.3083 - 1.918 0.47 - 324.6 1 2 0 -0.005 10 0 0 0 8.81E+07 3.88E+07 - - - 4.3288 0.8605 221125_WJC_METTL3_EV_vs_WT_F03.11355.11355.2 0.0452 20-Aug F.VVFDDSEPVQK.V "sp|Q13283|G3BP1_HUMAN,tr|A0A7I2YQF2|A0A7I2YQF2_HUMAN,tr|A0A7I2V5M7|A0A7I2V5M7_HUMAN,tr|A0A7I2V5H1|A0A7I2V5H1_HUMAN,tr|A0A7I2V565|A0A7I2V565_HUMAN,tr|A0A7I2YQN9|A0A7I2YQN9_HUMAN,tr|A0A7I2YQH0|A0A7I2YQH0_HUMAN,tr|A0A7I2V494|A0A7I2V494_HUMAN" 8 1261.619 1.41 27858 11355 2 1261.622915 631.8168 Ras GTPase-activating protein-binding protein 1 OS=Homo sapiens OX=9606 GN=G3BP1 PE=1 SV=1 4.03 2377.8 - 1.05E+06 - - - 3.077 - 1.658 0.34 - 67.9 1 1 0 0.0039 11 0 0 0 2.18E+07 1.54E+07 - - - 2.9188 0.9953 221125_WJC_METTL3_EV_vs_WT_F03.11358.11358.2 0.043 12-Aug R.WTETYVR[166.11].W "sp|P55884|EIF3B_HUMAN,tr|C9JQN7|C9JQN7_HUMAN,tr|C9JZG1|C9JZG1_HUMAN" 3 963.469 1.06 27859 11358 2 963.4674 482.7418 Eukaryotic translation initiation factor 3 subunit B OS=Homo sapiens OX=9606 GN=EIF3B PE=1 SV=3 6 2378.2 - 4.39E+06 - - - -1.6098 - 1.247 0.242 - 200.3 1 2 0 -0.0016 7 0 0 0 4.98E+07 4.70E+07 - - - 1.5274 0.9786 221125_WJC_METTL3_EV_vs_WT_F03.11360.11360.2 4.3 12-Jul K.TLDINVK.A "sp|Q6PKH6|DR4L2_HUMAN,sp|Q9BTZ2|DHRS4_HUMAN,tr|H0YLE1|H0YLE1_HUMAN,tr|A0A087WSZ6|A0A087WSZ6_HUMAN,tr|A0A087WXI8|A0A087WXI8_HUMAN,tr|H0YKN3|H0YKN3_HUMAN" 6 801.4596 1.44 27860 11360 2 801.458887 401.7371 Dehydrogenase\reductase SDR family member 4-like 2 OS=Homo sapiens OX=9606 GN=DHRS4L2 PE=2 SV=2 5.5 2378.4 - 3.91E+06 - - - -0.9133 - 1.1 0.117 - 169.2 1 2 0 -0.0007 7 0 0 0 1.36E+09 9.43E+08 - - - 0.2069 0.9982 221125_WJC_METTL3_EV_vs_WT_F03.11362.11362.2 0.00969 20-Oct K.LVPGLQDSEEK[136.11].R sp|Q9BSM1|PCGF1_HUMAN 1 1221.6332 6.81 27862 11362 2 1221.630493 611.8239 Polycomb group RING finger protein 1 OS=Homo sapiens OX=9606 GN=PCGF1 PE=1 SV=2 4.14 2378.6 - 1.23E+06 - - - -2.2429 - 1.687 0.301 - 294.9 1 2 0 -0.0027 11 0 0 0 1.05E+08 1.54E+07 - - - 2.678 0.9997 221125_WJC_METTL3_EV_vs_WT_F03.11365.11365.2 0.000566 16-Oct K.DGPGFYTTR.C "sp|P40939|ECHA_HUMAN,tr|H0YFD6|H0YFD6_HUMAN,tr|A0A2R8Y4F5|A0A2R8Y4F5_HUMAN" 3 1012.4614 0.93 27863 11365 2 1012.460719 507.238 "Trifunctional enzyme subunit alpha, mitochondrial OS=Homo sapiens OX=9606 GN=HADHA PE=1 SV=2" 5.84 2379 - 1.99E+06 - - - -0.6825 - 1.788 0.422 - 389.8 1 2 0 -0.0007 9 0 0 0 5.30E+07 5.71E+07 - - - 3.8388 0.975 221125_WJC_METTL3_EV_vs_WT_F03.11367.11367.2 0.000105 20-Sep F.VVFDDSEPVQK[136.11].V "sp|Q13283|G3BP1_HUMAN,tr|A0A7I2YQF2|A0A7I2YQF2_HUMAN,tr|A0A7I2V5M7|A0A7I2V5M7_HUMAN,tr|A0A7I2V5H1|A0A7I2V5H1_HUMAN,tr|A0A7I2V565|A0A7I2V565_HUMAN,tr|A0A7I2YQN9|A0A7I2YQN9_HUMAN,tr|A0A7I2YQH0|A0A7I2YQH0_HUMAN,tr|A0A7I2V494|A0A7I2V494_HUMAN" 8 1269.6332 1.41 27864 11367 2 1269.631576 635.8239 Ras GTPase-activating protein-binding protein 1 OS=Homo sapiens OX=9606 GN=G3BP1 PE=1 SV=1 4.03 2379.2 - 772195 - - - -1.3051 - 1.579 0.443 - 227.2 1 1 0 -0.0017 11 0 0 0 2.18E+07 1.54E+07 - - - 3.5482 0.9996 221125_WJC_METTL3_EV_vs_WT_F03.11369.11369.2 0.0149 16-Aug K.LQTPNTFPK.R "sp|Q14978|NOLC1_HUMAN,tr|A0A0A0MRM9|A0A0A0MRM9_HUMAN" 2 1044.5604 1.83 27865 11369 2 1044.559184 523.2875 Nucleolar and coiled-body phosphoprotein 1 OS=Homo sapiens OX=9606 GN=NOLC1 PE=1 SV=2 8.75 2379.4 - 1.03E+07 - - - -1.1593 - 1.835 0.366 - 216.9 1 2 0 -0.0012 9 0 0 0 1.18E+09 6.45E+08 - - - 3.5001 0.9953 221125_WJC_METTL3_EV_vs_WT_F03.11379.11379.2 0.559 12-Jul K.TLDINVK[136.11].A "sp|Q6PKH6|DR4L2_HUMAN,sp|Q9BTZ2|DHRS4_HUMAN,tr|H0YLE1|H0YLE1_HUMAN,tr|A0A087WSZ6|A0A087WSZ6_HUMAN,tr|A0A087WXI8|A0A087WXI8_HUMAN,tr|H0YKN3|H0YKN3_HUMAN" 6 809.4738 1.44 27873 11379 2 809.47308 405.7442 Dehydrogenase\reductase SDR family member 4-like 2 OS=Homo sapiens OX=9606 GN=DHRS4L2 PE=2 SV=2 5.5 2380.7 - 1.13E+07 - - - -0.9129 - 1.355 0.169 - 147.4 1 2 0 -0.0007 7 0 0 0 1.36E+09 9.44E+08 - - - 1.2516 0.9591 221125_WJC_METTL3_EV_vs_WT_F03.11381.11381.2 1.12 14-Jul R.EIISNLAK.A sp|O75533|SF3B1_HUMAN 1 886.5124 1.06 27875 11381 2 886.511601 444.2635 Splicing factor 3B subunit 1 OS=Homo sapiens OX=9606 GN=SF3B1 PE=1 SV=3 6.1 2380.8 - 2.60E+06 - - - -0.8821 - 1.248 0.009 - 136.6 1 2 0 -0.0008 8 0 0 0 1.29E+08 1.21E+08 - - - -0.2246 0.9988 221125_WJC_METTL3_EV_vs_WT_F03.11383.11383.2 3.19E-06 18-Nov K.YDSGIPPYSR.A "sp|Q13303|KCAB2_HUMAN,tr|A0A590UJJ4|A0A590UJJ4_HUMAN,tr|A0A5F9UN28|A0A5F9UN28_HUMAN,tr|A0A590UJB6|A0A590UJB6_HUMAN" 4 1153.5404 0.85 27877 11383 2 1153.537329 577.7775 Voltage-gated potassium channel subunit beta-2 OS=Homo sapiens OX=9606 GN=KCNAB2 PE=1 SV=2 5.83 2381.1 - 605902 - - - -2.6518 - 2.217 0.297 - 343.2 1 2 0 -0.0031 10 0 0 0 4.35E+07 5.10E+07 - - - 3.456 0.9994 221125_WJC_METTL3_EV_vs_WT_F03.11386.11386.2 0.000114 20-Dec R.LDSSAVLDTGK[136.11].Y "sp|P42704|LPPRC_HUMAN,tr|A0A804HI14|A0A804HI14_HUMAN,tr|A0A804HL40|A0A804HL40_HUMAN,tr|A0A804HKJ0|A0A804HKJ0_HUMAN,tr|A0A804HKR3|A0A804HKR3_HUMAN,tr|A0A804HIN4|A0A804HIN4_HUMAN,tr|A0A804HLG8|A0A804HLG8_HUMAN,tr|A0A804HHY9|A0A804HHY9_HUMAN,tr|A0A804HJH8|A0A804HJH8_HUMAN,tr|B8ZZ38|B8ZZ38_HUMAN,tr|A0A804HI40|A0A804HI40_HUMAN,tr|A0A804HJZ1|A0A804HJZ1_HUMAN,tr|C9JCA9|C9JCA9_HUMAN,tr|A0A804HIQ7|A0A804HIQ7_HUMAN,tr|A0A804HK30|A0A804HK30_HUMAN,tr|A0A804HKI2|A0A804HKI2_HUMAN,tr|A0A804HJI0|A0A804HJI0_HUMAN,tr|A0A804HIG4|A0A804HIG4_HUMAN,tr|A0A804HK02|A0A804HK02_HUMAN" 19 1112.5805 2.02 27878 11386 2 1112.577416 557.2975 "Leucine-rich PPR motif-containing protein, mitochondrial OS=Homo sapiens OX=9606 GN=LRPPRC PE=1 SV=3" 4.21 2381.5 - 909971 - - - -2.7441 - 2.312 0.421 - 379.8 1 2 0 -0.0031 11 0 0 0 2.84E+07 1.41E+07 - - - 4.4168 0.9998 221125_WJC_METTL3_EV_vs_WT_F03.11388.11388.2 0.000117 18-Oct K.AEAPLLTQTR[166.11].L sp|Q9BWG6|SCNM1_HUMAN 1 1108.6116 1.19 27880 11388 2 1108.611093 555.3131 Sodium channel modifier 1 OS=Homo sapiens OX=9606 GN=SCNM1 PE=1 SV=1 6.05 2381.7 - 1.21E+06 - - - -0.451 - 1.873 0.432 - 373.8 1 2 0 -0.0005 10 0 0 0 4.98E+07 4.19E+07 - - - 3.9833 0.9936 221125_WJC_METTL3_EV_vs_WT_F03.11393.11393.2 0.69 14-Aug R.K[136.11]LLASLVK[136.11].R "sp|Q13263|TIF1B_HUMAN,tr|M0R3C0|M0R3C0_HUMAN" 2 886.6186 0.81 27883 11393 2 886.61704 444.3166 Transcription intermediary factor 1-beta OS=Homo sapiens OX=9606 GN=TRIM28 PE=1 SV=5 10 2382.4 - 4.17E+06 - - - -1.8035 - 1.322 0.203 - 166.6 1 2 0 -0.0016 8 0 0 0 9.71E+07 1.20E+08 - - - 1.3817 0.9774 221125_WJC_METTL3_EV_vs_WT_F03.11394.11394.2 0.145 18-Jul K.AGFAGDQIPK[136.11].Y "sp|P61163|ACTZ_HUMAN,sp|P42025|ACTY_HUMAN,tr|R4GMT0|R4GMT0_HUMAN,tr|A0A1B0GVS3|A0A1B0GVS3_HUMAN" 4 1010.5276 1.84 27884 11394 2 1010.525539 506.2711 Alpha-centractin OS=Homo sapiens OX=9606 GN=ACTR1A PE=1 SV=1 5.88 2382.4 - 2.36E+06 - - - -2.0841 - 1.165 0.156 - 121 1 2 0 -0.0021 10 0 0 0 2.11E+08 1.15E+08 - - - 0.6188 0.9994 221125_WJC_METTL3_EV_vs_WT_F03.11395.11395.2 0.0183 16-Sep K.LQTPNTFPK[136.11].R "sp|Q14978|NOLC1_HUMAN,tr|A0A0A0MRM9|A0A0A0MRM9_HUMAN" 2 1052.5746 1.83 27885 11395 2 1052.573969 527.2946 Nucleolar and coiled-body phosphoprotein 1 OS=Homo sapiens OX=9606 GN=NOLC1 PE=1 SV=2 8.75 2382.5 - 2.80E+06 - - - -0.5947 - 1.669 0.323 - 244.8 1 2 0 -0.0006 9 0 0 0 1.18E+09 6.47E+08 - - - 2.9084 0.9982 221125_WJC_METTL3_EV_vs_WT_F03.11396.11396.2 1.49 14-Oct R.KLLASLVK.R "sp|Q13263|TIF1B_HUMAN,tr|M0R3C0|M0R3C0_HUMAN" 2 870.5902 0.79 27886 11396 2 870.588889 436.3024 Transcription intermediary factor 1-beta OS=Homo sapiens OX=9606 GN=TRIM28 PE=1 SV=5 10 2382.6 - 2.51E+06 - - - -1.5507 - 1.768 0.206 - 293.5 1 2 0 -0.0014 8 0 0 0 9.48E+07 1.20E+08 - - - 2.2807 0.9998 221125_WJC_METTL3_EV_vs_WT_F03.11397.11397.2 3.69E-05 18-Oct K.YYDDTYPSVK.E "sp|P61923|COPZ1_HUMAN,tr|F8VVA7|F8VVA7_HUMAN,tr|F8VYE0|F8VYE0_HUMAN,tr|F8W156|F8W156_HUMAN,tr|F8VYZ4|F8VYZ4_HUMAN,tr|F8VUC5|F8VUC5_HUMAN,tr|F8VXB1|F8VXB1_HUMAN,tr|F8VXR1|F8VXR1_HUMAN" 8 1249.5503 0.71 27887 11397 2 1249.548412 625.7824 Coatomer subunit zeta-1 OS=Homo sapiens OX=9606 GN=COPZ1 PE=1 SV=1 4.21 2382.7 - 1.40E+06 - - - -1.4981 - 1.57 0.612 - 197.2 1 2 0 -0.0019 10 0 0 0 5.59E+07 7.85E+07 - - - 4.8197 0.9987 221125_WJC_METTL3_EV_vs_WT_F03.11398.11398.3 5.12E-05 Dec-48 K.ILPAAALASEHSK[136.11].G "sp|Q7Z6E9|RBBP6_HUMAN,tr|H3BSK8|H3BSK8_HUMAN,tr|A0A2R8Y880|A0A2R8Y880_HUMAN" 3 1314.7387 1.04 27888 11398 3 1314.731928 439.2535 E3 ubiquitin-protein ligase RBBP6 OS=Homo sapiens OX=9606 GN=RBBP6 PE=1 SV=1 6.75 2382.8 - 1.20E+06 - - - -5.1516 - 2.233 0.433 - 194.8 1 2 0 -0.0068 13 0 0 0 2.01E+07 1.93E+07 - - - 5.5437 0.9997 221125_WJC_METTL3_EV_vs_WT_F03.11403.11403.2 3.98E-06 16-Sep K.EGVLYVGSK.T "sp|Q16143|SYUB_HUMAN,sp|P37840|SYUA_HUMAN,tr|A0A669KB41|A0A669KB41_HUMAN,tr|D6RA31|D6RA31_HUMAN,tr|A0A669KBH5|A0A669KBH5_HUMAN,tr|E7EPV7|E7EPV7_HUMAN" 6 950.5073 1.46 27891 11403 2 950.506892 476.2609 Beta-synuclein OS=Homo sapiens OX=9606 GN=SNCB PE=1 SV=1 6.1 2383.4 - 3.34E+07 - - - -0.4261 - 1.776 0.405 - 341 1 2 0 -0.0004 9 0 0 0 3.44E+09 2.35E+09 - - - 3.6939 0.9996 221125_WJC_METTL3_EV_vs_WT_F03.11405.11405.2 0.0486 16-Oct R.QLDNIVGER.G sp|P04259|K2C6B_HUMAN 1 1042.5407 3504.41 27893 11405 2 1042.540154 522.2776 "Keratin, type II cytoskeletal 6B OS=Homo sapiens OX=9606 GN=KRT6B PE=1 SV=5" 4.37 2383.5 - 5.49E+06 - - - -0.5458 - 2.036 0.288 - 612.6 1 2 0 -0.0006 9 0 0 0 4.63E+09 1.32E+06 - - - 3.2249 0.9999 221125_WJC_METTL3_EV_vs_WT_F03.11407.11407.2 8.66E-07 18-Sep K.YYDDTYPSVK[136.11].E "sp|P61923|COPZ1_HUMAN,tr|F8VVA7|F8VVA7_HUMAN,tr|F8VYE0|F8VYE0_HUMAN,tr|F8W156|F8W156_HUMAN,tr|F8VYZ4|F8VYZ4_HUMAN,tr|F8VUC5|F8VUC5_HUMAN,tr|F8VXB1|F8VXB1_HUMAN,tr|F8VXR1|F8VXR1_HUMAN" 8 1257.5645 1.27 27895 11407 2 1257.564207 629.7895 Coatomer subunit zeta-1 OS=Homo sapiens OX=9606 GN=COPZ1 PE=1 SV=1 4.21 2383.7 - 1.34E+06 - - - -0.2203 - 1.54 0.617 - 116.1 1 2 0 -0.0003 10 0 0 0 5.21E+07 4.11E+07 - - - 4.8033 0.9999 221125_WJC_METTL3_EV_vs_WT_F03.11413.11413.2 3.27E-05 18-Nov R.VDEMSQDIVK.Y "sp|O15372|EIF3H_HUMAN,tr|B3KS98|B3KS98_HUMAN,tr|A0A087WZK9|A0A087WZK9_HUMAN,tr|E5RJT0|E5RJT0_HUMAN" 4 1162.554 1.97 27899 11413 2 1162.554185 582.2843 Eukaryotic translation initiation factor 3 subunit H OS=Homo sapiens OX=9606 GN=EIF3H PE=1 SV=1 4.03 2384.5 - 1.05E+07 - - - 0.1677 - 2.362 0.474 - 633.7 1 2 0 0.0002 10 0 0 0 2.19E+08 1.11E+08 - - - 4.9411 0.9975 221125_WJC_METTL3_EV_vs_WT_F03.11414.11414.2 0.0504 14-Jul K.NFVDPVTK.K sp|P15924|DESP_HUMAN 1 918.4811 6.36 27900 11414 2 918.480133 460.2478 Desmoplakin OS=Homo sapiens OX=9606 GN=DSP PE=1 SV=3 5.84 2384.6 - 8.19E+06 - - - -1.0343 - 1.343 0.25 - 261.4 1 2 0 -0.0009 8 0 0 0 3.12E+08 4.90E+07 - - - 1.7766 0.9995 221125_WJC_METTL3_EV_vs_WT_F03.11415.11415.2 0.0152 18-Aug K.AGFAGDQIPK.Y "sp|P61163|ACTZ_HUMAN,sp|P42025|ACTY_HUMAN,tr|R4GMT0|R4GMT0_HUMAN,tr|A0A1B0GVS3|A0A1B0GVS3_HUMAN" 4 1002.5134 1.79 27901 11415 2 1002.513863 502.264 Alpha-centractin OS=Homo sapiens OX=9606 GN=ACTR1A PE=1 SV=1 5.88 2384.6 - 7.15E+06 - - - 0.417 - 1.378 0.416 - 143.5 1 2 0 0.0004 10 0 0 0 2.11E+08 1.18E+08 - - - 3.0084 0.9957 221125_WJC_METTL3_EV_vs_WT_F03.11416.11416.2 0.00545 18-Jul R.VDEMSQDIVK[136.11].Y "sp|O15372|EIF3H_HUMAN,tr|B3KS98|B3KS98_HUMAN,tr|A0A087WZK9|A0A087WZK9_HUMAN,tr|E5RJT0|E5RJT0_HUMAN" 4 1170.5682 1.96 27902 11416 2 1170.572314 586.2914 Eukaryotic translation initiation factor 3 subunit H OS=Homo sapiens OX=9606 GN=EIF3H PE=1 SV=1 4.03 2384.6 - 5.02E+06 - - - 3.5231 - 1.574 0.335 - 205.4 1 2 0 0.0041 10 0 0 0 2.18E+08 1.11E+08 - - - 2.7802 0.982 221125_WJC_METTL3_EV_vs_WT_F03.11417.11417.2 2.88 14-Jul R.EIISNLAK[136.11].A sp|O75533|SF3B1_HUMAN 1 894.5266 1.06 27903 11417 2 894.526143 448.2706 Splicing factor 3B subunit 1 OS=Homo sapiens OX=9606 GN=SF3B1 PE=1 SV=3 6.1 2384.7 - 4.53E+06 - - - -0.4919 - 1.094 0.126 - 145.2 1 2 0 -0.0004 8 0 0 0 1.29E+08 1.21E+08 - - - 0.2425 0.9912 221125_WJC_METTL3_EV_vs_WT_F03.11420.11420.2 2.17E-06 16-Oct L.MSALESMC[160.03]K.E "sp|P78347|GTF2I_HUMAN,tr|C9J6M0|C9J6M0_HUMAN,tr|A0A494C1K3|A0A494C1K3_HUMAN" 3 1055.445 1.37 27906 11420 2 1055.446116 528.7298 General transcription factor II-I OS=Homo sapiens OX=9606 GN=GTF2I PE=1 SV=2 5.75 2384.9 - 1.28E+06 - - - 1.083 - 2.017 0.543 - 385.6 1 1 0 0.0011 9 0 0 0 4.37E+07 3.18E+07 - - - 5.081 0.9676 221125_WJC_METTL3_EV_vs_WT_F03.11421.11421.2 2.73 12-Jun K.DYPDYYK.L "sp|Q86U86|PB1_HUMAN,tr|H0Y5B5|H0Y5B5_HUMAN,tr|E7EVG2|E7EVG2_HUMAN" 3 962.4022 1.48 27907 11421 2 962.402886 482.2084 Protein polybromo-1 OS=Homo sapiens OX=9606 GN=PBRM1 PE=1 SV=1 4.21 2385 - 1.30E+06 - - - 0.7512 - 1.066 0.096 - 117.2 1 2 0 0.0007 7 0 0 0 3.54E+07 2.39E+07 - - - -0.0477 0.9918 221125_WJC_METTL3_EV_vs_WT_F03.11422.11422.2 0.0222 16-Sep K.LEEPPELNR[166.11].Q sp|Q7Z5L9|I2BP2_HUMAN 1 1105.5643 1.57 27908 11422 2 1105.568826 553.7894 Interferon regulatory factor 2-binding protein 2 OS=Homo sapiens OX=9606 GN=IRF2BP2 PE=1 SV=2 4.25 2385.1 - 1.02E+06 - - - 4.0866 - 1.47 0.325 - 343.6 1 2 0 0.0045 9 0 0 0 2.82E+08 1.80E+08 - - - 2.5546 0.9998 221125_WJC_METTL3_EV_vs_WT_F03.11427.11427.2 0.00363 18-Nov R.QVSGQLLEER.K sp|Q9Y6D9|MD1L1_HUMAN 1 1157.6041 1.77 27911 11427 2 1157.603729 579.8093 Mitotic spindle assembly checkpoint protein MAD1 OS=Homo sapiens OX=9606 GN=MAD1L1 PE=1 SV=2 4.53 2385.7 - 3.24E+06 - - - -0.2782 - 2.281 0.368 - 523.7 1 2 0 -0.0003 10 0 0 0 1.04E+08 5.86E+07 - - - 4.0607 0.9994 221125_WJC_METTL3_EV_vs_WT_F03.11428.11428.2 1.46 14-Aug R.EGLEETLR.N sp|P07196|NFL_HUMAN 1 945.4767 2.26 27912 11428 2 945.476265 473.7456 Neurofilament light polypeptide OS=Homo sapiens OX=9606 GN=NEFL PE=1 SV=3 4.25 2385.7 - 3.56E+06 - - - -0.4865 - 1.806 0.272 - 199.2 1 2 0 -0.0005 8 0 0 0 1.59E+08 7.06E+07 - - - 2.8326 0.9994 221125_WJC_METTL3_EV_vs_WT_F03.11430.11430.2 0.00504 18-Nov K.QLAALNC[160.03]SVR.D sp|Q9UKX7|NUP50_HUMAN 1 1130.5866 0.75 27914 11430 2 1130.58708 566.3006 Nuclear pore complex protein Nup50 OS=Homo sapiens OX=9606 GN=NUP50 PE=1 SV=2 8.25 2385.8 - 1.37E+06 - - - 0.4007 - 1.993 0.263 - 457.6 1 2 0 0.0005 10 0 0 0 1.86E+07 2.47E+07 - - - 2.9084 0.9967 221125_WJC_METTL3_EV_vs_WT_F03.11432.11432.2 0.24 16-Jun R.VELSTGMPR.R "sp|Q16629|SRSF7_HUMAN,tr|C9JAB2|C9JAB2_HUMAN,tr|A0A0B4J1Z1|A0A0B4J1Z1_HUMAN" 3 988.5012 1.75 27915 11432 2 988.500633 495.2579 Serine\arginine-rich splicing factor 7 OS=Homo sapiens OX=9606 GN=SRSF7 PE=1 SV=1 5.97 2386.1 - 4.31E+06 - - - -0.5392 - 1.573 0.164 - 142.3 2 2 0 -0.0005 9 0 0 0 1.42E+08 8.12E+07 - - - 1.4282 0.9941 221125_WJC_METTL3_EV_vs_WT_F03.11434.11434.2 0.631 18-Aug K.SLLSAEEAAK.Q sp|Q7KZF4|SND1_HUMAN 1 1017.5342 5.2 27916 11434 2 1017.5338 509.7744 Staphylococcal nuclease domain-containing protein 1 OS=Homo sapiens OX=9606 GN=SND1 PE=1 SV=1 4.53 2386.3 - 2.28E+06 - - - -0.4324 - 1.238 0.184 - 141.4 1 2 0 -0.0004 10 0 0 0 7.32E+07 1.41E+07 - - - 0.9958 0.998 221125_WJC_METTL3_EV_vs_WT_F03.11441.11441.2 0.00108 14-Aug R.EGLEETLR[166.11].N sp|P07196|NFL_HUMAN 1 955.485 2.33 27920 11441 2 955.484539 478.7498 Neurofilament light polypeptide OS=Homo sapiens OX=9606 GN=NEFL PE=1 SV=3 4.25 2387.1 - 2.52E+06 - - - -0.4772 - 1.798 0.136 - 207.9 1 2 0 -0.0005 8 0 0 0 1.65E+08 7.06E+07 - - - 1.8147 0.9997 221125_WJC_METTL3_EV_vs_WT_F03.11445.11445.2 0.00148 18-Nov R.IAAC[160.03]QEQILR[166.11].Y sp|Q9BRP1|PDD2L_HUMAN 1 1210.6368 0.56 27924 11445 2 1210.635559 606.3257 Programmed cell death protein 2-like OS=Homo sapiens OX=9606 GN=PDCD2L PE=1 SV=1 5.99 2387.6 - 888219 - - - -0.9937 - 2.156 0.336 - 588.3 1 2 0 -0.0012 10 0 0 0 1.08E+07 1.93E+07 - - - 3.6668 0.9996 221125_WJC_METTL3_EV_vs_WT_F03.11446.11446.2 0.000972 18-Nov K.FQEAGELYNR[166.11].M "sp|Q14690|RRP5_HUMAN,tr|A0A3B3IUD7|A0A3B3IUD7_HUMAN" 2 1235.581 0.74 27925 11446 2 1235.579653 618.7978 Protein RRP5 homolog OS=Homo sapiens OX=9606 GN=PDCD11 PE=1 SV=3 4.53 2387.7 - 612012 - - - -1.1072 - 2.087 0.325 - 307.1 1 2 0 -0.0014 10 0 0 0 1.48E+07 2.00E+07 - - - 3.4947 0.9973 221125_WJC_METTL3_EV_vs_WT_F03.11450.11450.2 0.0287 16-Oct K.LEEPPELNR.Q sp|Q7Z5L9|I2BP2_HUMAN 1 1095.556 1.44 27927 11450 2 1095.551687 548.7853 Interferon regulatory factor 2-binding protein 2 OS=Homo sapiens OX=9606 GN=IRF2BP2 PE=1 SV=2 4.25 2388.2 - 6.02E+06 - - - -3.9715 - 2.177 0.312 - 512.1 1 2 0 -0.0044 9 0 0 0 2.83E+08 1.96E+08 - - - 3.5947 0.9997 221125_WJC_METTL3_EV_vs_WT_F03.11451.11451.2 9.72E-05 16-Aug R.SLVNLGGSK.S sp|P04264|K2C1_HUMAN 1 873.492 -1 27928 11451 2 873.490868 437.7533 "Keratin, type II cytoskeletal 1 OS=Homo sapiens OX=9606 GN=KRT1 PE=1 SV=6" 8.47 2388.3 - 3.34E+06 - - - -1.2753 - 1.674 0.458 - 199.4 1 2 0 -0.0011 9 0 0 0 0.00E+00 0.00E+00 - - - 3.914 0.9982 221125_WJC_METTL3_EV_vs_WT_F03.11456.11456.2 0.0533 12-Jul K.SSLPNFK.Q "sp|Q9UNH7|SNX6_HUMAN,tr|A0A0A0MRI2|A0A0A0MRI2_HUMAN,tr|H0YJF8|H0YJF8_HUMAN,tr|G3V5U2|G3V5U2_HUMAN,tr|G3V4Z5|G3V4Z5_HUMAN" 5 791.4178 1.92 27931 11456 2 791.416693 396.7162 Sorting nexin-6 OS=Homo sapiens OX=9606 GN=SNX6 PE=1 SV=1 8.47 2388.8 - 2.13E+06 - - - -1.3406 - 1.375 0.283 - 145.1 1 2 0 -0.0011 7 0 0 0 5.89E+07 3.07E+07 - - - 2.1399 0.9998 221125_WJC_METTL3_EV_vs_WT_F03.11457.11457.2 0.00162 18-Nov R.VENNDLVIAR[166.11].L "sp|Q9NZW5|PALS2_HUMAN,tr|C9J4Q3|C9J4Q3_HUMAN,tr|B8ZZG1|B8ZZG1_HUMAN,tr|C9JGI8|C9JGI8_HUMAN" 4 1151.6174 1.79 27932 11457 2 1151.619267 576.816 Protein PALS2 OS=Homo sapiens OX=9606 GN=PALS2 PE=1 SV=2 4.37 2388.9 - 872776 - - - 1.6151 - 2.53 0.459 - 655.2 1 2 0 0.0019 10 0 0 0 5.68E+07 3.17E+07 - - - 5.0215 0.9997 221125_WJC_METTL3_EV_vs_WT_F03.11458.11458.2 0.00787 18-Dec K.FQEAGELYNR.M "sp|Q14690|RRP5_HUMAN,tr|A0A3B3IUD7|A0A3B3IUD7_HUMAN" 2 1225.5728 0.74 27933 11458 2 1225.570807 613.7937 Protein RRP5 homolog OS=Homo sapiens OX=9606 GN=PDCD11 PE=1 SV=3 4.53 2389.1 - 915352 - - - -1.5862 - 1.907 0.428 - 298.2 1 2 0 -0.0019 10 0 0 0 1.48E+07 2.00E+07 - - - 4.0035 0.9987 221125_WJC_METTL3_EV_vs_WT_F03.11459.11459.2 0.00408 20-Sep R.IHGSVALETLR.Q "sp|P42694|HELZ_HUMAN,tr|J3QS41|J3QS41_HUMAN" 2 1194.6721 3.15 27934 11459 2 1194.674009 598.3433 Probable helicase with zinc finger domain OS=Homo sapiens OX=9606 GN=HELZ PE=1 SV=2 6.75 2389.2 - 692716 - - - 1.6222 - 1.824 0.273 - 248.2 1 2 0 0.0019 11 0 0 0 2.22E+07 7.06E+06 - - - 2.6827 0.9999 221125_WJC_METTL3_EV_vs_WT_F03.11462.11462.3 7.38E-05 13/40 R.IHGSVALETLR.Q "sp|P42694|HELZ_HUMAN,tr|J3QS41|J3QS41_HUMAN" 2 1194.6721 2.16 27935 11462 3 1194.670938 399.2313 Probable helicase with zinc finger domain OS=Homo sapiens OX=9606 GN=HELZ PE=1 SV=2 6.75 2389.6 - 3.02E+06 - - - -0.9484 - 2.618 0.389 - 264 1 2 0 -0.0011 11 0 0 0 8.79E+07 4.06E+07 - - - 5.6107 0.9997 221125_WJC_METTL3_EV_vs_WT_F03.11463.11463.2 0.0265 16-Dec K.LIDIGNSC[160.03]R[166.11].T "sp|O00139|KIF2A_HUMAN,tr|D6R9M0|D6R9M0_HUMAN,tr|A0A6Q8PFA6|A0A6Q8PFA6_HUMAN,tr|A0A6Q8PGH7|A0A6Q8PGH7_HUMAN,tr|H0Y8H2|H0Y8H2_HUMAN,tr|A0A6Q8PG37|A0A6Q8PG37_HUMAN,tr|A0A6Q8PH57|A0A6Q8PH57_HUMAN" 7 1056.5261 2.03 27936 11463 2 1056.526533 529.2704 Kinesin-like protein KIF2A OS=Homo sapiens OX=9606 GN=KIF2A PE=1 SV=3 5.83 2389.7 - 2.06E+06 - - - 0.3635 - 2.074 0.363 - 417.5 1 2 0 0.0004 9 0 0 0 9.89E+07 4.87E+07 - - - 3.8324 0.9937 221125_WJC_METTL3_EV_vs_WT_F03.11465.11465.2 6.49E-05 22-Oct N.LFASGEGDYSTR.H sp|P13674|P4HA1_HUMAN 1 1301.5888 1.67 27938 11465 2 1301.589009 651.8017 Prolyl 4-hydroxylase subunit alpha-1 OS=Homo sapiens OX=9606 GN=P4HA1 PE=1 SV=2 4.37 2389.9 - 383964 - - - 0.1644 - 2.077 0.567 - 327.8 1 1 0 0.0002 12 0 0 0 5.83E+06 3.49E+06 - - - 5.152 0.9998 221125_WJC_METTL3_EV_vs_WT_F03.11468.11468.2 8.69E-05 13/18 R.QVSGQLLEER[166.11].K sp|Q9Y6D9|MD1L1_HUMAN 1 1167.6123 1.77 27939 11468 2 1167.610817 584.8134 Mitotic spindle assembly checkpoint protein MAD1 OS=Homo sapiens OX=9606 GN=MAD1L1 PE=1 SV=2 4.53 2390.4 - 1.51E+06 - - - -1.2881 - 2.34 0.397 - 667.9 1 2 0 -0.0015 10 0 0 0 1.04E+08 5.86E+07 - - - 4.3458 0.9998 221125_WJC_METTL3_EV_vs_WT_F03.11469.11469.2 0.000948 18-Sep R.ELAAGAFGTK.K "sp|Q14527|HLTF_HUMAN,tr|A0A0C4DGA6|A0A0C4DGA6_HUMAN" 2 963.5025 0.94 27940 11469 2 963.502078 482.7585 Helicase-like transcription factor OS=Homo sapiens OX=9606 GN=HLTF PE=1 SV=2 6.1 2390.4 - 1.24E+06 - - - -0.4857 - 1.952 0.472 - 239.8 1 2 0 -0.0005 10 0 0 0 1.89E+08 2.01E+08 - - - 4.394 0.9594 221125_WJC_METTL3_EV_vs_WT_F03.11476.11476.2 0.0203 14-Jul R.YPDGIISK[136.11].P sp|Q86U44|MTA70_HUMAN 1 899.4844 0.01 27944 11476 2 899.484298 450.7495 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 5.83 2391.3 - 3.55E+06 - - - -0.0945 - 1.44 0.344 - 139.4 1 1 0 -0.0001 8 0 0 0 5.33E+05 7.93E+07 - - - 2.6815 0.9995 221125_WJC_METTL3_EV_vs_WT_F03.11477.11477.2 0.0415 20-Aug R.EAALGAGFSDK.T "sp|P55084|ECHB_HUMAN,tr|C9JE81|C9JE81_HUMAN,tr|F5GZQ3|F5GZQ3_HUMAN,tr|B5MD38|B5MD38_HUMAN,tr|C9JEY0|C9JEY0_HUMAN" 5 1064.5138 1.3 27945 11477 2 1064.515037 533.2642 "Trifunctional enzyme subunit beta, mitochondrial OS=Homo sapiens OX=9606 GN=HADHB PE=1 SV=3" 4.37 2391.3 - 2.35E+06 - - - 1.1254 - 1.767 0.373 - 135.3 1 2 0 0.0012 11 0 0 0 4.34E+07 3.33E+07 - - - 3.3356 0.9998 221125_WJC_METTL3_EV_vs_WT_F03.11478.11478.2 0.0118 18-Nov K.IGAVEEELNR[166.11].V "sp|P52732|KIF11_HUMAN,tr|A0A7I2YQY4|A0A7I2YQY4_HUMAN,tr|A0A7I2V3A9|A0A7I2V3A9_HUMAN,tr|A0A7I2V3V3|A0A7I2V3V3_HUMAN" 4 1138.5858 4.67 27946 11478 2 1138.585331 570.3002 Kinesin-like protein KIF11 OS=Homo sapiens OX=9606 GN=KIF11 PE=1 SV=2 4.25 2391.4 - 3.28E+06 - - - -0.3873 - 2.275 0.405 - 558.7 1 2 0 -0.0004 10 0 0 0 4.77E+09 1.02E+09 - - - 4.3266 0.9976 221125_WJC_METTL3_EV_vs_WT_F03.11479.11479.2 0.0292 14-Jul R.QVPFNEVR[166.11].L "sp|P51114|FXR1_HUMAN,tr|C9JAJ4|C9JAJ4_HUMAN,tr|B4DXZ6|B4DXZ6_HUMAN" 3 997.5221 1.23 27947 11479 2 997.520944 499.7683 Fragile X mental retardation syndrome-related protein 1 OS=Homo sapiens OX=9606 GN=FXR1 PE=1 SV=3 6 2391.4 - 3.10E+06 - - - -1.1087 - 1.323 0.263 - 251.6 1 2 0 -0.0011 8 0 0 0 2.94E+08 2.39E+08 - - - 1.8273 0.9931 221125_WJC_METTL3_EV_vs_WT_F03.11483.11483.2 0.0327 16-Aug R.NYYGYQGYR[166.11].- sp|Q1KMD3|HNRL2_HUMAN 1 1192.5177 1.63 27949 11483 2 1192.515145 597.2661 Heterogeneous nuclear ribonucleoprotein U-like protein 2 OS=Homo sapiens OX=9606 GN=HNRNPUL2 PE=1 SV=1 8.43 2391.9 - 1.02E+06 - - - -2.1367 - 1.183 0.267 - 227.1 1 2 0 -0.0025 9 0 0 0 1.18E+08 7.26E+07 - - - 1.4984 0.9998 221125_WJC_METTL3_EV_vs_WT_F03.11484.11484.2 3.36E-06 20-Oct R.GYPDTAALENR.Q "sp|Q9Y618|NCOR2_HUMAN,tr|C9J7T7|C9J7T7_HUMAN,tr|C9JE98|C9JE98_HUMAN,tr|H7C1J7|H7C1J7_HUMAN,tr|C9J0Q5|C9J0Q5_HUMAN,tr|A0A384DVL6|A0A384DVL6_HUMAN" 6 1205.5677 1.74 27950 11484 2 1205.565832 603.7911 Nuclear receptor corepressor 2 OS=Homo sapiens OX=9606 GN=NCOR2 PE=1 SV=3 4.37 2392 - 984069 - - - -1.5213 - 2.025 0.545 - 401 1 2 0 -0.0018 11 0 0 0 5.62E+07 3.22E+07 - - - 4.9745 0.9912 221125_WJC_METTL3_EV_vs_WT_F03.11485.11485.2 0.303 12-Jun K.SMIEISR[166.11].T "sp|P49368|TCPG_HUMAN,tr|E9PM09|E9PM09_HUMAN,tr|Q5SZW8|Q5SZW8_HUMAN,tr|E9PRC8|E9PRC8_HUMAN,tr|B4DUR8|B4DUR8_HUMAN,tr|Q5SZX9|Q5SZX9_HUMAN,tr|Q5SZX6|Q5SZX6_HUMAN" 7 844.4352 0.21 27951 11485 2 844.434053 423.2249 T-complex protein 1 subunit gamma OS=Homo sapiens OX=9606 GN=CCT3 PE=1 SV=4 5.72 2392 - 2.60E+07 - - - -1.3678 - 1.242 0.166 - 198.4 1 2 0 -0.0012 7 0 0 0 2.66E+08 1.28E+09 - - - 0.9534 0.9994 221125_WJC_METTL3_EV_vs_WT_F03.11486.11486.2 0.023 12-Jul K.SGEIWAR.F "sp|Q12996|CSTF3_HUMAN,tr|E9PLP8|E9PLP8_HUMAN" 2 817.4083 1.21 27952 11486 2 817.407007 409.7114 Cleavage stimulation factor subunit 3 OS=Homo sapiens OX=9606 GN=CSTF3 PE=1 SV=1 5.72 2392.1 - 1.31E+06 - - - -1.5231 - 1.771 0.337 - 245.2 1 2 0 -0.0012 7 0 0 0 3.66E+07 3.02E+07 - - - 3.3407 0.9997 221125_WJC_METTL3_EV_vs_WT_F03.11487.11487.2 9.86E-05 16-Sep R.NYYGYQGYR.- sp|Q1KMD3|HNRL2_HUMAN 1 1182.5094 1.63 27953 11487 2 1182.507791 592.262 Heterogeneous nuclear ribonucleoprotein U-like protein 2 OS=Homo sapiens OX=9606 GN=HNRNPUL2 PE=1 SV=1 8.43 2392.2 - 796118 - - - -1.3801 - 1.598 0.526 - 297.2 1 2 0 -0.0016 9 0 0 0 1.18E+08 7.26E+07 - - - 4.2817 0.9997 221125_WJC_METTL3_EV_vs_WT_F03.11490.11490.2 9.40E-05 20-Oct R.GYPDTAALENR[166.11].Q "sp|Q9Y618|NCOR2_HUMAN,tr|C9J7T7|C9J7T7_HUMAN,tr|C9JE98|C9JE98_HUMAN,tr|H7C1J7|H7C1J7_HUMAN,tr|C9J0Q5|C9J0Q5_HUMAN,tr|A0A384DVL6|A0A384DVL6_HUMAN" 6 1215.5759 1.66 27956 11490 2 1215.578329 608.7952 Nuclear receptor corepressor 2 OS=Homo sapiens OX=9606 GN=NCOR2 PE=1 SV=3 4.37 2392.6 - 320026 - - - 1.9686 - 2.078 0.479 - 387.6 1 2 0 0.0024 11 0 0 0 5.66E+07 3.41E+07 - - - 4.5568 0.9993 221125_WJC_METTL3_EV_vs_WT_F03.11493.11493.2 0.0278 18-Jul R.ELAAGAFGTK[136.11].K "sp|Q14527|HLTF_HUMAN,tr|A0A0C4DGA6|A0A0C4DGA6_HUMAN" 2 971.5167 0.99 27957 11493 2 971.514749 486.7656 Helicase-like transcription factor OS=Homo sapiens OX=9606 GN=HLTF PE=1 SV=2 6.1 2393 - 3.60E+06 - - - -2.0555 - 1.778 0.38 - 190.2 1 2 0 -0.002 10 0 0 0 1.86E+08 1.88E+08 - - - 3.4534 0.9996 221125_WJC_METTL3_EV_vs_WT_F03.11495.11495.2 0.00197 18-Sep R.LSSPVPAVC[160.03]R.K "sp|O75792|RNH2A_HUMAN,tr|A0A2R8Y606|A0A2R8Y606_HUMAN,tr|A0A2R8Y658|A0A2R8Y658_HUMAN" 3 1084.5699 1.87 27959 11495 2 1084.569465 543.2922 Ribonuclease H2 subunit A OS=Homo sapiens OX=9606 GN=RNASEH2A PE=1 SV=2 8.25 2393.2 - 5.02E+06 - - - -0.4149 - 1.813 0.342 - 232.1 1 2 0 -0.0004 10 0 0 0 2.09E+08 1.12E+08 - - - 3.2276 0.9997 221125_WJC_METTL3_EV_vs_WT_F03.11496.11496.2 0.000718 20-Aug K.ELSANTAAFAK.S sp|O60749|SNX2_HUMAN 1 1121.5717 0.01 27960 11496 2 1121.571066 561.7931 Sorting nexin-2 OS=Homo sapiens OX=9606 GN=SNX2 PE=1 SV=2 6.1 2393.3 - 841863 - - - -0.5546 - 1.697 0.41 - 149.2 1 2 0 -0.0006 11 0 0 0 3.09E+07 2.55E+09 - - - 3.4998 0.9996 221125_WJC_METTL3_EV_vs_WT_F03.11498.11498.2 9.25E-06 22-Nov K.VMETQAQVDELK[136.11].G sp|P51809|VAMP7_HUMAN 1 1397.6952 1.2 27962 11498 2 1397.691251 699.8549 Vesicle-associated membrane protein 7 OS=Homo sapiens OX=9606 GN=VAMP7 PE=1 SV=3 4.14 2393.5 - 606379 - - - -2.8118 - 2.413 0.538 - 325.3 1 2 0 -0.0039 12 0 0 0 1.44E+07 1.19E+07 - - - 5.3312 0.9999 221125_WJC_METTL3_EV_vs_WT_F03.11502.11502.2 0.00247 16-Oct R.LNDFASTVR.L "sp|P20674|COX5A_HUMAN,tr|H3BNX8|H3BNX8_HUMAN,tr|H3BV69|H3BV69_HUMAN,tr|H3BRM5|H3BRM5_HUMAN" 4 1021.5193 1.72 27963 11502 2 1021.518279 511.7669 "Cytochrome c oxidase subunit 5A, mitochondrial OS=Homo sapiens OX=9606 GN=COX5A PE=1 SV=2" 5.84 2394.1 - 5.94E+06 - - - -0.9594 - 2.28 0.5 - 405.1 1 2 0 -0.001 9 0 0 0 5.67E+08 3.31E+08 - - - 5.1181 1 221125_WJC_METTL3_EV_vs_WT_F03.11503.11503.2 2.56E-05 14/22 K.VMETQAQVDELK.G sp|P51809|VAMP7_HUMAN 1 1389.681 1.2 27964 11503 2 1389.680833 695.8478 Vesicle-associated membrane protein 7 OS=Homo sapiens OX=9606 GN=VAMP7 PE=1 SV=3 4.14 2394.2 - 1.10E+06 - - - -0.1065 - 2.781 0.555 - 619.3 1 2 0 -0.0001 12 0 0 0 1.44E+07 1.19E+07 - - - 5.8314 0.9994 221125_WJC_METTL3_EV_vs_WT_F03.11505.11505.2 1.00E-07 20-Dec K.QAEESMVASMR.L "sp|Q8N6H7|ARFG2_HUMAN,tr|E9PIY6|E9PIY6_HUMAN,tr|E9PQP3|E9PQP3_HUMAN,tr|G5E9L0|G5E9L0_HUMAN,tr|A0A0D9SF70|A0A0D9SF70_HUMAN" 5 1237.5431 0.54 27966 11505 2 1237.538506 619.7788 ADP-ribosylation factor GTPase-activating protein 2 OS=Homo sapiens OX=9606 GN=ARFGAP2 PE=1 SV=1 4.53 2394.4 - 793719 - - - -3.7179 - 2.127 0.613 - 485.8 1 2 0 -0.0046 11 0 0 0 2.10E+07 3.91E+07 - - - 5.6088 0.9994 221125_WJC_METTL3_EV_vs_WT_F03.11506.11506.2 0.00782 24-Nov K.VEPGLGADNSVVR.F "sp|P21333|FLNA_HUMAN,tr|A0A7P0NMY4|A0A7P0NMY4_HUMAN,tr|Q60FE5|Q60FE5_HUMAN" 3 1311.6783 1.08 27967 11506 2 1311.678701 656.8464 Filamin-A OS=Homo sapiens OX=9606 GN=FLNA PE=1 SV=4 4.37 2394.6 - 622045 - - - 0.3217 - 1.908 0.304 - 301.3 1 2 0 0.0004 13 0 0 0 7.33E+07 6.81E+07 - - - 2.9443 0.9895 221125_WJC_METTL3_EV_vs_WT_F03.11509.11509.2 0.0994 16-Jul K.DPVSSLQVK[136.11].A sp|Q9P032|NDUF4_HUMAN 1 979.543 1.09 27968 11509 2 979.543493 490.7788 NADH dehydrogenase [ubiquinone] 1 alpha subcomplex assembly factor 4 OS=Homo sapiens OX=9606 GN=NDUFAF4 PE=1 SV=1 5.84 2395 - 2.72E+06 - - - 0.5431 - 1.422 0.099 - 185.6 2 2 0 0.0005 9 0 0 0 3.78E+08 3.47E+08 - - - 0.6561 0.9996 221125_WJC_METTL3_EV_vs_WT_F03.11512.11512.2 8.77E-05 13/24 K.VEPGLGADNSVVR[166.11].F "sp|P21333|FLNA_HUMAN,tr|A0A7P0NMY4|A0A7P0NMY4_HUMAN,tr|Q60FE5|Q60FE5_HUMAN" 3 1321.6865 1.08 27971 11512 2 1321.683843 661.8506 Filamin-A OS=Homo sapiens OX=9606 GN=FLNA PE=1 SV=4 4.37 2395.4 - 951480 - - - -2.0474 - 2.141 0.46 - 354.2 1 2 0 -0.0027 13 0 0 0 7.33E+07 6.81E+07 - - - 4.3915 0.9999 221125_WJC_METTL3_EV_vs_WT_F03.11517.11517.2 2.03E-06 20-Oct K.QAEESMVASMR[166.11].L "sp|Q8N6H7|ARFG2_HUMAN,tr|E9PIY6|E9PIY6_HUMAN,tr|E9PQP3|E9PQP3_HUMAN,tr|G5E9L0|G5E9L0_HUMAN,tr|A0A0D9SF70|A0A0D9SF70_HUMAN" 5 1247.5514 0.43 27974 11517 2 1247.550836 624.783 ADP-ribosylation factor GTPase-activating protein 2 OS=Homo sapiens OX=9606 GN=ARFGAP2 PE=1 SV=1 4.53 2396 - 582885 - - - -0.4336 - 2.11 0.604 - 447 1 2 0 -0.0005 11 0 0 0 2.10E+07 4.91E+07 - - - 5.5219 0.979 221125_WJC_METTL3_EV_vs_WT_F03.11521.11521.2 0.467 12-Jul K.QEAFSIR.M sp|P15924|DESP_HUMAN 1 849.4345 12.46 27976 11521 2 849.431066 425.7245 Desmoplakin OS=Homo sapiens OX=9606 GN=DSP PE=1 SV=3 6 2396.4 - 3.10E+06 - - - -4.0038 - 1.452 0.198 - 260 1 2 0 -0.0034 7 0 0 0 3.13E+08 2.51E+07 - - - 1.684 0.9948 221125_WJC_METTL3_EV_vs_WT_F03.11522.11522.2 0.903 12-Jul K.TLVDIAK[136.11].S "sp|Q99832|TCPH_HUMAN,sp|Q9H2S1|KCNN2_HUMAN,tr|F8WAM2|F8WAM2_HUMAN,tr|A0A3F2YNY5|A0A3F2YNY5_HUMAN,tr|A0A0J9YW81|A0A0J9YW81_HUMAN,tr|A0A669KBH3|A0A669KBH3_HUMAN" 6 766.468 0.11 27977 11522 2 766.467817 384.2413 T-complex protein 1 subunit eta OS=Homo sapiens OX=9606 GN=CCT7 PE=1 SV=2 5.5 2396.5 - 2.52E+06 - - - -0.2453 - 1.33 0.152 - 184.6 1 2 0 -0.0002 7 0 0 0 1.04E+07 9.19E+07 - - - 1.0672 0.9995 221125_WJC_METTL3_EV_vs_WT_F03.11524.11524.2 2.83E-05 22-Nov K.LTGLGQSNAALR.E sp|Q08378|GOGA3_HUMAN 1 1199.6622 2.65 27978 11524 2 1199.660784 600.8384 Golgin subfamily A member 3 OS=Homo sapiens OX=9606 GN=GOLGA3 PE=1 SV=2 9.75 2396.7 - 1.04E+06 - - - -1.2095 - 1.984 0.343 - 355.1 1 2 0 -0.0015 12 0 0 0 2.37E+07 8.92E+06 - - - 3.3766 0.9998 221125_WJC_METTL3_EV_vs_WT_F03.11528.11528.2 0.00699 20-Oct K.GDAMIMEETGK[136.11].L "sp|Q9UQ80|PA2G4_HUMAN,tr|F8W0A3|F8W0A3_HUMAN,tr|F8VR77|F8VR77_HUMAN,tr|H0YIN7|H0YIN7_HUMAN" 4 1188.5246 0.89 27981 11528 2 1188.523348 595.2696 Proliferation-associated protein 2G4 OS=Homo sapiens OX=9606 GN=PA2G4 PE=1 SV=3 4.14 2397.1 - 2.78E+06 - - - -1.0618 - 2.196 0.453 - 432.1 1 2 0 -0.0013 11 0 0 0 7.25E+07 8.16E+07 - - - 4.5145 0.9824 221125_WJC_METTL3_EV_vs_WT_F03.11529.11529.2 0.0218 20-Aug R.VVDNEGTLQLK[136.11].R "sp|Q9H1Z4|WDR13_HUMAN,tr|A0A087X091|A0A087X091_HUMAN" 2 1222.6649 1.18 27982 11529 2 1222.660716 612.3397 WD repeat-containing protein 13 OS=Homo sapiens OX=9606 GN=WDR13 PE=1 SV=2 4.37 2397.2 - 488754 - - - -3.395 - 1.309 0.232 - 100.1 1 2 0 -0.0042 11 0 0 0 4.97E+07 4.21E+07 - - - 1.4817 0.9988 221125_WJC_METTL3_EV_vs_WT_F03.11532.11532.2 0.000407 15/22 R.VGEPVALSEEER[166.11].L "sp|Q13435|SF3B2_HUMAN,tr|E9PPJ0|E9PPJ0_HUMAN,tr|E9PIL8|E9PIL8_HUMAN,tr|H0YCG1|H0YCG1_HUMAN,tr|E9PJ04|E9PJ04_HUMAN,tr|E9PJT3|E9PJT3_HUMAN" 6 1323.6546 1.15 27983 11532 2 1323.648532 662.8346 Splicing factor 3B subunit 2 OS=Homo sapiens OX=9606 GN=SF3B2 PE=1 SV=2 4.09 2397.6 - 1.43E+06 - - - -4.5692 - 2.848 0.525 - 899.8 1 2 0 -0.006 12 0 0 0 2.42E+08 2.10E+08 - - - 5.6706 0.9917 221125_WJC_METTL3_EV_vs_WT_F03.11534.11534.2 2.50E-05 13/22 R.VGEPVALSEEER.L "sp|Q13435|SF3B2_HUMAN,tr|E9PPJ0|E9PPJ0_HUMAN,tr|E9PIL8|E9PIL8_HUMAN,tr|H0YCG1|H0YCG1_HUMAN,tr|E9PJ04|E9PJ04_HUMAN,tr|E9PJT3|E9PJT3_HUMAN" 6 1313.6463 1.15 27984 11534 2 1313.637148 657.8304 Splicing factor 3B subunit 2 OS=Homo sapiens OX=9606 GN=SF3B2 PE=1 SV=2 4.09 2397.7 - 1.55E+06 - - - -6.9745 - 2.381 0.498 - 537.2 1 2 0 -0.0092 12 0 0 0 2.42E+08 2.10E+08 - - - 4.9989 0.8875 221125_WJC_METTL3_EV_vs_WT_F03.11538.11538.2 1.23 16-Jun K.YSGTLNLDR[166.11].V "sp|P49327|FAS_HUMAN,tr|A0A0U1RQF0|A0A0U1RQF0_HUMAN" 2 1047.5224 0.77 27986 11538 2 1047.522467 524.7685 Fatty acid synthase OS=Homo sapiens OX=9606 GN=FASN PE=1 SV=3 5.84 2398.2 - 1.30E+07 - - - 0.022 - 1.025 0.006 - 94.8 2 2 0 0 9 0 0 0 8.23E+07 1.07E+08 - - - -0.9777 0.9999 221125_WJC_METTL3_EV_vs_WT_F03.11539.11539.2 3.76E-05 14/22 R.APASVLPAATPR[166.11].Q "sp|P13861|KAP2_HUMAN,tr|C9J830|C9J830_HUMAN" 2 1159.6589 2.2 27987 11539 2 1159.65828 580.8367 cAMP-dependent protein kinase type II-alpha regulatory subunit OS=Homo sapiens OX=9606 GN=PRKAR2A PE=1 SV=2 9.79 2398.4 - 871999 - - - -0.5148 - 2.712 0.494 - 629.8 1 2 0 -0.0006 12 0 0 0 2.10E+08 9.58E+07 - - - 5.3146 0.9548 221125_WJC_METTL3_EV_vs_WT_F03.11540.11540.2 14.4 16-Jul K.YSGTLNLDR.V "sp|P49327|FAS_HUMAN,tr|A0A0U1RQF0|A0A0U1RQF0_HUMAN" 2 1037.5142 0.78 27988 11540 2 1037.513492 519.7644 Fatty acid synthase OS=Homo sapiens OX=9606 GN=FASN PE=1 SV=3 5.84 2398.4 - 3.09E+06 - - - -0.6573 - 1.142 0.051 - 132.7 2 2 0 -0.0007 9 0 0 0 8.17E+07 1.05E+08 - - - -0.3329 0.9965 221125_WJC_METTL3_EV_vs_WT_F03.11541.11541.2 0.68 16-May R.DVYTGDALR.L sp|P20618|PSB1_HUMAN 1 1008.4876 1.22 27989 11541 2 1008.487045 505.2511 Proteasome subunit beta type-1 OS=Homo sapiens OX=9606 GN=PSMB1 PE=1 SV=2 4.21 2398.5 - 1.45E+06 - - - -0.5741 - 1.118 0.275 - 86.9 1 2 0 -0.0006 9 0 0 0 1.38E+08 1.13E+08 - - - 1.3947 0.9611 221125_WJC_METTL3_EV_vs_WT_F03.11544.11544.2 0.602 14-Sep S.LVNLGGSK.S sp|P04264|K2C1_HUMAN 1 786.46 5.01 27990 11544 2 786.459957 394.2373 "Keratin, type II cytoskeletal 1 OS=Homo sapiens OX=9606 GN=KRT1 PE=1 SV=6" 8.75 2398.9 - 3.95E+06 - - - 0.0051 - 1.828 0.253 - 202.6 1 1 0 0 8 0 0 0 1.28E+08 2.55E+07 - - - 2.7289 0.9072 221125_WJC_METTL3_EV_vs_WT_F03.11545.11545.2 2.65 16-Apr R.VEFMDDTSR.S sp|P62857|RS28_HUMAN 1 1098.4652 9.5 27991 11545 2 1098.465212 550.2399 40S ribosomal protein S28 OS=Homo sapiens OX=9606 GN=RPS28 PE=1 SV=1 4.03 2398.9 - 2.42E+06 - - - 0.0346 - 0.868 0.089 - 36.6 2 2 0 0 9 0 0 0 7.67E+07 8.07E+06 - - - -0.8457 0.9529 221125_WJC_METTL3_EV_vs_WT_F03.11546.11546.2 1.9 14-Jun R.QAGLSYIR.Y "sp|Q5VTU8|AT5EL_HUMAN,sp|P56381|ATP5E_HUMAN" 2 906.4923 1.92 27992 11546 2 906.492218 454.2534 "ATP synthase subunit epsilon-like protein, mitochondrial OS=Homo sapiens OX=9606 GN=ATP5F1EP2 PE=1 SV=1" 8.75 2399 - 2.11E+06 - - - -0.1081 - 1.2 0.019 - 128.6 2 2 0 -0.0001 8 0 0 0 4.17E+08 2.17E+08 - - - -0.4033 0.9999 221125_WJC_METTL3_EV_vs_WT_F03.11548.11548.2 0.000259 22-Nov K.LLAQQAGSGEFR.T "sp|A6NKD9|CC85C_HUMAN,tr|G3V4C8|G3V4C8_HUMAN,tr|H0YJY5|H0YJY5_HUMAN,tr|H0YJE0|H0YJE0_HUMAN" 4 1275.6571 2.51 27994 11548 2 1275.656459 638.8359 Coiled-coil domain-containing protein 85C OS=Homo sapiens OX=9606 GN=CCDC85C PE=1 SV=1 6 2399.2 - 795740 - - - -0.5409 - 2.246 0.528 - 437.5 1 2 0 -0.0007 12 0 0 0 4.19E+07 1.67E+07 - - - 5.0696 0.9997 221125_WJC_METTL3_EV_vs_WT_F03.11551.11551.2 0.000752 22-Dec R.ALEESNYELEGK.L "sp|P13645|K1C10_HUMAN,tr|A0A1B0GVI3|A0A1B0GVI3_HUMAN" 2 1380.6409 999 27995 11551 2 1380.637839 691.3277 "Keratin, type I cytoskeletal 10 OS=Homo sapiens OX=9606 GN=KRT10 PE=1 SV=6" 4.09 2399.6 - 4.00E+06 - - - -2.2098 - 2.35 0.462 - 386.3 1 2 0 -0.0031 12 0 0 0 4.45E+09 0.00E+00 - - - 4.7005 0.9995 221125_WJC_METTL3_EV_vs_WT_F03.11552.11552.2 0.0234 16-Aug K.VELSTVNVR.T sp|Q92665|RT31_HUMAN 1 1015.5662 0.97 27996 11552 2 1015.566669 508.7904 "28S ribosomal protein S31, mitochondrial OS=Homo sapiens OX=9606 GN=MRPS31 PE=1 SV=3" 5.97 2399.7 - 1.75E+06 - - - 0.4529 - 1.567 0.367 - 172.4 1 2 0 0.0005 9 0 0 0 2.42E+08 2.49E+08 - - - 3.051 0.9995 221125_WJC_METTL3_EV_vs_WT_F03.11553.11553.2 0.0438 14-Jul R.GNLANVIR[166.11].Y "sp|P12235|ADT1_HUMAN,sp|Q9H0C2|ADT4_HUMAN,sp|P05141|ADT2_HUMAN,sp|P12236|ADT3_HUMAN,tr|V9GYG0|V9GYG0_HUMAN" 5 865.5009 0.01 27997 11553 2 865.501472 433.7577 ADP\ATP translocase 1 OS=Homo sapiens OX=9606 GN=SLC25A4 PE=1 SV=4 9.75 2399.7 - 4.14E+06 - - - 0.6378 - 1.76 0.33 - 311.3 1 2 0 0.0006 8 0 0 0 3.57E+06 2.79E+08 - - - 3.1832 0.9618 221125_WJC_METTL3_EV_vs_WT_F03.11558.11558.2 3.55 14-Jul K.GITLSVRP.- tr|A0A075B6Z2|A0A075B6Z2_HUMAN 1 841.5022 1314987.32 28000 11558 2 841.501449 421.7584 T cell receptor alpha joining 56 (Fragment) OS=Homo sapiens OX=9606 GN=TRAJ56 PE=4 SV=1 9.75 2400.3 - 1.61E+07 - - - -0.8354 - 1.314 0.011 - 204.8 2 2 0 -0.0007 8 0 0 0 7.30E+11 5.55E+05 - - - -0.1889 0.9998 221125_WJC_METTL3_EV_vs_WT_F03.11561.11561.2 0.014 13/22 K.LLAQQAGSGEFR[166.11].T "sp|A6NKD9|CC85C_HUMAN,tr|G3V4C8|G3V4C8_HUMAN,tr|H0YJY5|H0YJY5_HUMAN,tr|H0YJE0|H0YJE0_HUMAN" 4 1285.6654 2.51 28003 11561 2 1285.666614 643.84 Coiled-coil domain-containing protein 85C OS=Homo sapiens OX=9606 GN=CCDC85C PE=1 SV=1 6 2400.6 - 606384 - - - 0.9295 - 2.556 0.438 - 629.3 1 2 0 0.0012 12 0 0 0 4.19E+07 1.67E+07 - - - 4.7449 0.9962 221125_WJC_METTL3_EV_vs_WT_F03.11566.11566.2 0.0173 16-Oct K.LLQSQLQVK[136.11].K "sp|Q96I25|SPF45_HUMAN,tr|Q5W010|Q5W010_HUMAN,tr|Q5W011|Q5W011_HUMAN" 3 1063.6481 0.99 28005 11566 2 1063.647609 532.8313 Splicing factor 45 OS=Homo sapiens OX=9606 GN=RBM17 PE=1 SV=1 8.75 2401.3 - 2.26E+06 - - - -0.4569 - 1.752 0.089 - 277.5 1 2 0 -0.0005 9 0 0 0 5.08E+07 5.10E+07 - - - 1.3205 0.8254 221125_WJC_METTL3_EV_vs_WT_F03.11567.11567.2 0.131 12-Jul N.SLEDVVR.L "sp|Q52LW3|RHG29_HUMAN,sp|Q14152|EIF3A_HUMAN,tr|F8VWZ8|F8VWZ8_HUMAN" 3 816.4341 1.27 28006 11567 2 816.434429 409.2243 Rho GTPase-activating protein 29 OS=Homo sapiens OX=9606 GN=ARHGAP29 PE=1 SV=2 4.37 2401.4 - 1.43E+06 - - - 0.3638 - 1.393 0.177 - 199.6 1 1 0 0.0003 7 0 0 0 4.77E+07 3.74E+07 - - - 1.3985 0.9999 221125_WJC_METTL3_EV_vs_WT_F03.11568.11568.2 0.000241 20-Nov R.FASGGC[160.03]DNLIK.L "sp|P55735|SEC13_HUMAN,tr|A8MXL6|A8MXL6_HUMAN" 2 1180.5547 1.46 28007 11568 2 1180.553865 591.2846 Protein SEC13 homolog OS=Homo sapiens OX=9606 GN=SEC13 PE=1 SV=3 5.83 2401.5 - 1.13E+06 - - - -0.6717 - 2.144 0.512 - 243.5 1 2 0 -0.0008 11 0 0 0 2.91E+07 1.99E+07 - - - 4.8856 0.9958 221125_WJC_METTL3_EV_vs_WT_F03.11569.11569.2 0.547 12-Jul K.TLVDIAK.S "sp|Q99832|TCPH_HUMAN,sp|Q9H2S1|KCNN2_HUMAN,tr|F8WAM2|F8WAM2_HUMAN,tr|A0A3F2YNY5|A0A3F2YNY5_HUMAN,tr|A0A0J9YW81|A0A0J9YW81_HUMAN,tr|A0A669KBH3|A0A669KBH3_HUMAN" 6 758.4538 0.11 28008 11569 2 758.452611 380.2342 T-complex protein 1 subunit eta OS=Homo sapiens OX=9606 GN=CCT7 PE=1 SV=2 5.5 2401.7 - 361225 - - - -1.5743 - 1.36 0.213 - 188.7 1 2 0 -0.0012 7 0 0 0 1.04E+07 9.19E+07 - - - 1.5881 0.9995 221125_WJC_METTL3_EV_vs_WT_F03.11572.11572.2 0.0157 16-Nov R.TLEPQELAR[166.11].L "sp|Q8WWM7|ATX2L_HUMAN,tr|H3BUF6|H3BUF6_HUMAN" 2 1065.5694 1.24 28009 11572 2 1065.57021 533.792 Ataxin-2-like protein OS=Homo sapiens OX=9606 GN=ATXN2L PE=1 SV=2 4.53 2402.1 - 2.30E+06 - - - 0.7658 - 1.824 0.326 - 399.2 1 2 0 0.0008 9 0 0 0 1.04E+08 8.41E+07 - - - 3.1874 0.9997 221125_WJC_METTL3_EV_vs_WT_F03.11580.11580.2 0.00478 18-Nov K.IEEAC[160.03]EIYAR.A "sp|P54920|SNAA_HUMAN,tr|M0R2M1|M0R2M1_HUMAN,tr|M0R0Y2|M0R0Y2_HUMAN" 3 1252.5758 0.99 28014 11580 2 1252.573936 627.2952 Alpha-soluble NSF attachment protein OS=Homo sapiens OX=9606 GN=NAPA PE=1 SV=3 4.25 2403.1 - 894789 - - - -1.4786 - 2.221 0.367 - 397.4 1 2 0 -0.0019 10 0 0 0 2.38E+07 2.40E+07 - - - 3.9784 0.9997 221125_WJC_METTL3_EV_vs_WT_F03.11582.11582.2 0.000158 18-Oct K.GNIIISTPEK[136.11].W sp|O75643|U520_HUMAN 1 1078.6114 2.06 28016 11582 2 1078.609977 540.313 U5 small nuclear ribonucleoprotein 200 kDa helicase OS=Homo sapiens OX=9606 GN=SNRNP200 PE=1 SV=2 6 2403.2 - 1.55E+06 - - - -1.2961 - 1.966 0.428 - 401 1 2 0 -0.0014 10 0 0 0 1.20E+08 5.84E+07 - - - 4.0887 0.9996 221125_WJC_METTL3_EV_vs_WT_F03.11586.11586.2 0.00111 18-Sep K.GNIIISTPEK.W sp|O75643|U520_HUMAN 1 1070.5972 2.05 28018 11586 2 1070.598356 536.3059 U5 small nuclear ribonucleoprotein 200 kDa helicase OS=Homo sapiens OX=9606 GN=SNRNP200 PE=1 SV=2 6 2403.8 - 2.47E+06 - - - 1.1031 - 1.883 0.376 - 381.9 1 2 0 0.0012 10 0 0 0 1.20E+08 5.86E+07 - - - 3.5843 0.9777 221125_WJC_METTL3_EV_vs_WT_F03.11588.11588.2 2.47E-06 16-Sep S.YVAFTDTER[166.11].L "sp|P48741|HSP77_HUMAN,sp|P54652|HSP72_HUMAN,sp|P0DMV8|HS71A_HUMAN,sp|P34931|HS71L_HUMAN,sp|P11142|HSP7C_HUMAN,sp|P0DMV9|HS71B_HUMAN,sp|P17066|HSP76_HUMAN,tr|E9PQQ4|E9PQQ4_HUMAN,tr|E9PNE6|E9PNE6_HUMAN,tr|E9PKE3|E9PKE3_HUMAN,tr|E9PLF4|E9PLF4_HUMAN,tr|Q53FA3|Q53FA3_HUMAN,tr|E9PI65|E9PI65_HUMAN,tr|E9PK54|E9PK54_HUMAN,tr|E9PN25|E9PN25_HUMAN,tr|E9PPY6|E9PPY6_HUMAN,tr|E9PQK7|E9PQK7_HUMAN,tr|A0A0G2JIW1|A0A0G2JIW1_HUMAN" 18 1110.5221 0.24 28019 11588 2 1110.525114 556.2683 Putative heat shock 70 kDa protein 7 OS=Homo sapiens OX=9606 GN=HSPA7 PE=5 SV=2 4.37 2404 - 1.32E+06 - - - 2.7059 - 1.901 0.581 - 243 1 1 0 0.003 9 0 0 0 5.50E+07 2.27E+08 - - - 5.1898 0.9985 221125_WJC_METTL3_EV_vs_WT_F03.11589.11589.2 0.00553 16-Oct R.VC[160.03]EIQATLR.E "sp|Q9BTA9|WAC_HUMAN,tr|A0A7P0T961|A0A7P0T961_HUMAN,tr|A0A0A0MRT2|A0A0A0MRT2_HUMAN" 3 1088.5648 1.5 28020 11589 2 1088.561513 545.2897 WW domain-containing adapter protein with coiled-coil OS=Homo sapiens OX=9606 GN=WAC PE=1 SV=3 5.97 2404.1 - 1.02E+06 - - - -3.0462 - 2.079 0.317 - 462.1 1 2 0 -0.0033 9 0 0 0 3.16E+07 2.10E+07 - - - 3.4987 0.9999 221125_WJC_METTL3_EV_vs_WT_F03.11591.11591.2 1.49E-06 18-Dec R.LGPGLVDQER.S "sp|O15417|TNC18_HUMAN,tr|H9KVB4|H9KVB4_HUMAN,tr|H7C3U5|H7C3U5_HUMAN" 3 1082.572 2.01 28022 11591 2 1082.572339 542.2933 Trinucleotide repeat-containing gene 18 protein OS=Homo sapiens OX=9606 GN=TNRC18 PE=1 SV=3 4.37 2404.3 - 1.18E+06 - - - 0.2919 - 2.253 0.526 - 512.9 1 2 0 0.0003 10 0 0 0 1.65E+08 8.20E+07 - - - 5.1932 0.9996 221125_WJC_METTL3_EV_vs_WT_F03.11594.11594.2 0.0447 18-Oct R.QLMAQQELDR[166.11].L "sp|Q86UP3|ZFHX4_HUMAN,sp|Q15911|ZFHX3_HUMAN,tr|E7EVZ1|E7EVZ1_HUMAN" 3 1240.6109 1.36 28025 11594 2 1240.611501 621.3127 Zinc finger homeobox protein 4 OS=Homo sapiens OX=9606 GN=ZFHX4 PE=1 SV=1 4.37 2404.7 - 485598 - - - 0.4514 - 1.911 0.338 - 435.9 1 2 0 0.0006 10 0 0 0 1.12E+07 8.21E+06 - - - 3.345 0.9997 221125_WJC_METTL3_EV_vs_WT_F03.11595.11595.2 0.00155 18-Dec R.QLMAQQELDR.L "sp|Q86UP3|ZFHX4_HUMAN,sp|Q15911|ZFHX3_HUMAN,tr|E7EVZ1|E7EVZ1_HUMAN" 3 1230.6027 1.36 28026 11595 2 1230.604332 616.3086 Zinc finger homeobox protein 4 OS=Homo sapiens OX=9606 GN=ZFHX4 PE=1 SV=1 4.37 2404.8 - 470560 - - - 1.3497 - 2.261 0.38 - 848.6 1 2 0 0.0017 10 0 0 0 1.12E+07 8.21E+06 - - - 4.1243 0.9998 221125_WJC_METTL3_EV_vs_WT_F03.11599.11599.2 0.000799 16-Sep R.YDEMVESMK[136.11].K "sp|P62258|1433E_HUMAN,tr|B4DJF2|B4DJF2_HUMAN,tr|I3L3T1|I3L3T1_HUMAN" 3 1138.4766 0.77 28028 11599 2 1138.477415 570.2456 14-3-3 protein epsilon OS=Homo sapiens OX=9606 GN=YWHAE PE=1 SV=1 4.14 2405.3 - 1.69E+06 - - - 0.7185 - 1.803 0.447 - 219.8 1 2 0 0.0008 9 0 0 0 6.00E+07 7.80E+07 - - - 4.0476 0.9994 221125_WJC_METTL3_EV_vs_WT_F03.11600.11600.2 0.00179 16-Aug R.VC[160.03]EIQATLR[166.11].E "sp|Q9BTA9|WAC_HUMAN,tr|A0A7P0T961|A0A7P0T961_HUMAN,tr|A0A0A0MRT2|A0A0A0MRT2_HUMAN" 3 1098.5731 1.48 28029 11600 2 1098.572948 550.2938 WW domain-containing adapter protein with coiled-coil OS=Homo sapiens OX=9606 GN=WAC PE=1 SV=3 5.97 2405.4 - 919962 - - - -0.1375 - 1.802 0.283 - 190.2 1 2 0 -0.0002 9 0 0 0 3.08E+07 2.08E+07 - - - 2.8349 0.9985 221125_WJC_METTL3_EV_vs_WT_F03.11601.11601.2 0.000543 18-Oct K.IEEAC[160.03]EIYAR[166.11].A "sp|P54920|SNAA_HUMAN,tr|M0R2M1|M0R2M1_HUMAN,tr|M0R0Y2|M0R0Y2_HUMAN" 3 1262.5841 2.01 28030 11601 2 1262.588833 632.2993 Alpha-soluble NSF attachment protein OS=Homo sapiens OX=9606 GN=NAPA PE=1 SV=3 4.25 2405.6 - 768755 - - - 3.7819 - 2.06 0.423 - 199 1 2 0 0.0048 10 0 0 0 2.28E+07 1.13E+07 - - - 4.1811 0.9996 221125_WJC_METTL3_EV_vs_WT_F03.11605.11605.2 0.000206 13/22 R.APASVLPAATPR.Q "sp|P13861|KAP2_HUMAN,tr|C9J830|C9J830_HUMAN" 2 1149.6506 2.18 28032 11605 2 1149.653735 575.8326 cAMP-dependent protein kinase type II-alpha regulatory subunit OS=Homo sapiens OX=9606 GN=PRKAR2A PE=1 SV=2 9.79 2406.1 - 7.85E+06 - - - 2.7208 - 2.309 0.504 - 551.8 1 2 0 0.0031 12 0 0 0 1.88E+08 8.60E+07 - - - 4.9644 0.9967 221125_WJC_METTL3_EV_vs_WT_F03.11606.11606.2 0.302 14-Jul K.AALEEFSR.V sp|Q92922|SMRC1_HUMAN 1 921.4556 2.89 28033 11606 2 921.456542 461.7351 SWI\SNF complex subunit SMARCC1 OS=Homo sapiens OX=9606 GN=SMARCC1 PE=1 SV=3 4.53 2406.1 - 1.98E+06 - - - 1.0266 - 1.382 0.217 - 134.1 1 2 0 0.0009 8 0 0 0 2.78E+08 9.63E+07 - - - 1.6192 0.8324 221125_WJC_METTL3_EV_vs_WT_F03.11607.11607.2 0.366 18-Aug R.LSQLGLDAGK.L sp|Q15750|TAB1_HUMAN 1 1000.5553 4.4 28034 11607 2 1001.56052 501.2849 TGF-beta-activated kinase 1 and MAP3K7-binding protein 1 OS=Homo sapiens OX=9606 GN=TAB1 PE=1 SV=1 5.84 2406.2 - 1.46E+06 - - - 1004.6521 - 1.6 0.222 - 132.5 1 2 0 1.0052 10 0 0 0 3.90E+07 8.86E+06 - - - 1.677 0.9975 221125_WJC_METTL3_EV_vs_WT_F03.11608.11608.2 0.012 14-Sep R.TGIPTLGK.N "sp|P13995|MTDC_HUMAN,tr|A0A7I2V2U6|A0A7I2V2U6_HUMAN,tr|A0A7I2YQD4|A0A7I2YQD4_HUMAN,tr|B8ZZU9|B8ZZU9_HUMAN" 4 785.4647 1.04 28035 11608 2 785.465501 393.7396 "Bifunctional methylenetetrahydrofolate dehydrogenase\cyclohydrolase, mitochondrial OS=Homo sapiens OX=9606 GN=MTHFD2 PE=1 SV=2" 8.41 2406.3 - 1.37E+06 - - - 1.0147 - 1.579 0.193 - 197.2 1 2 0 0.0008 8 0 0 0 2.57E+08 2.46E+08 - - - 1.8439 0.9999 221125_WJC_METTL3_EV_vs_WT_F03.11609.11609.2 0.000196 20-Dec K.SEMEVQDAELK[136.11].A sp|Q9UQ80|PA2G4_HUMAN 1 1285.5951 0.01 28036 11609 2 1285.593841 643.8048 Proliferation-associated protein 2G4 OS=Homo sapiens OX=9606 GN=PA2G4 PE=1 SV=3 4 2406.4 - 443659 - - - -1.005 - 2.416 0.555 - 590 1 2 0 -0.0013 11 0 0 0 1.21E+05 9.19E+06 - - - 5.5261 0.9995 221125_WJC_METTL3_EV_vs_WT_F03.11610.11610.2 7.82E-05 22-Aug K.YIETSELC[160.03]GGAR[166.11].L sp|O00429|DNM1L_HUMAN 1 1364.627 0.69 28037 11610 2 1364.623669 683.3208 Dynamin-1-like protein OS=Homo sapiens OX=9606 GN=DNM1L PE=1 SV=2 4.53 2406.5 - 364936 - - - -2.43 - 1.763 0.525 - 156.6 1 2 0 -0.0033 12 0 0 0 4.27E+06 6.15E+06 - - - 4.4095 0.9992 221125_WJC_METTL3_EV_vs_WT_F03.11613.11613.2 0.000618 14-Sep R.QAGLSYIR[166.11].Y "sp|Q5VTU8|AT5EL_HUMAN,sp|P56381|ATP5E_HUMAN" 2 916.5006 1.9 28039 11613 2 916.49876 459.2576 "ATP synthase subunit epsilon-like protein, mitochondrial OS=Homo sapiens OX=9606 GN=ATP5F1EP2 PE=1 SV=1" 8.75 2406.9 - 9.69E+06 - - - -1.9924 - 1.703 0.37 - 324.4 1 2 0 -0.0018 8 0 0 0 4.15E+08 2.18E+08 - - - 3.3789 0.9953 221125_WJC_METTL3_EV_vs_WT_F03.11617.11617.2 1.24 14-Jul K.SISISVAR.G sp|P04264|K2C1_HUMAN 1 831.4814 5.55 28042 11617 2 831.481115 416.748 "Keratin, type II cytoskeletal 1 OS=Homo sapiens OX=9606 GN=KRT1 PE=1 SV=6" 9.47 2407.2 - 3.61E+06 - - - -0.3632 - 1.472 0.128 - 132.7 1 2 0 -0.0003 8 0 0 0 2.34E+10 4.22E+09 - - - 1.1523 0.9906 221125_WJC_METTL3_EV_vs_WT_F03.11620.11620.2 0.0119 18-Nov K.VFTDPSNLQR[166.11].H "sp|Q03112|MECOM_HUMAN,sp|Q9HAZ2|PRD16_HUMAN,tr|H9KVD4|H9KVD4_HUMAN,tr|E7EUL6|E7EUL6_HUMAN,tr|A0A0C3SFZ7|A0A0C3SFZ7_HUMAN,tr|D6RDW0|D6RDW0_HUMAN,tr|D6RFY3|D6RFY3_HUMAN,tr|H0YA13|H0YA13_HUMAN" 8 1185.6018 1.15 28045 11620 2 1185.600918 593.8082 Histone-lysine N-methyltransferase MECOM OS=Homo sapiens OX=9606 GN=MECOM PE=1 SV=3 5.81 2407.5 - 1.42E+06 - - - -0.7077 - 1.773 0.028 - 429.6 2 2 0 -0.0008 10 0 0 0 4.11E+07 3.57E+07 - - - 0.7116 0.9999 221125_WJC_METTL3_EV_vs_WT_F03.11625.11625.2 2.62E-07 13/24 K.ITESVAETAQTIK[136.11].K sp|Q96A49|SYAP1_HUMAN 1 1397.7493 1.33 28050 11625 2 1397.750166 699.8819 Synapse-associated protein 1 OS=Homo sapiens OX=9606 GN=SYAP1 PE=1 SV=1 4.53 2408.1 - 603909 - - - 0.6017 - 2.628 0.466 - 596 1 2 0 0.0008 13 0 0 0 2.45E+08 1.84E+08 - - - 4.9625 0.8224 221125_WJC_METTL3_EV_vs_WT_F03.11628.11628.2 0.159 14-Jun L.EPLVLDGK.E "sp|Q12851|M4K2_HUMAN,tr|H7C208|H7C208_HUMAN" 2 869.4858 0.96 28051 11628 2 869.485505 435.7502 Mitogen-activated protein kinase kinase kinase kinase 2 OS=Homo sapiens OX=9606 GN=MAP4K2 PE=1 SV=2 4.37 2408.5 - 3.26E+07 - - - -0.3784 - 1.246 0.223 - 153.4 1 1 0 -0.0003 8 0 0 0 1.49E+09 1.54E+09 - - - 1.3513 0.9996 221125_WJC_METTL3_EV_vs_WT_F03.11633.11633.2 1.07E-06 15/24 K.ITESVAETAQTIK.K sp|Q96A49|SYAP1_HUMAN 1 1389.7351 1.33 28056 11633 2 1389.731159 695.8748 Synapse-associated protein 1 OS=Homo sapiens OX=9606 GN=SYAP1 PE=1 SV=1 4.53 2408.9 - 1.01E+06 - - - -2.8538 - 2.75 0.528 - 788.7 1 2 0 -0.004 13 0 0 0 2.45E+08 1.84E+08 - - - 5.5359 0.9998 221125_WJC_METTL3_EV_vs_WT_F03.11634.11634.2 3.16E-05 20-Sep R.VTQSNFAVGYK[136.11].T "sp|P21796|VDAC1_HUMAN,tr|C9JI87|C9JI87_HUMAN" 2 1220.6281 1.26 28057 11634 2 1220.630312 611.3213 Voltage-dependent anion-selective channel protein 1 OS=Homo sapiens OX=9606 GN=VDAC1 PE=1 SV=2 8.56 2409 - 995635 - - - 1.822 - 2.144 0.527 - 358.2 1 2 0 0.0022 11 0 0 0 3.42E+07 2.71E+07 - - - 4.9959 0.9998 221125_WJC_METTL3_EV_vs_WT_F03.11640.11640.2 0.0648 18-Nov K.VDALLSAQPK[136.11].G sp|Q9NYU2|UGGG1_HUMAN 1 1048.6008 0.17 28061 11640 2 1048.600404 525.3077 UDP-glucose:glycoprotein glucosyltransferase 1 OS=Homo sapiens OX=9606 GN=UGGT1 PE=1 SV=3 5.81 2409.7 - 2.37E+06 - - - -0.3872 - 2.446 0.37 - 604.6 1 2 0 -0.0004 10 0 0 0 1.78E+07 1.05E+08 - - - 4.2704 0.9987 221125_WJC_METTL3_EV_vs_WT_F03.11641.11641.2 0.0497 14-Jul R.TGIPTLGK[136.11].N "sp|P13995|MTDC_HUMAN,tr|A0A7I2V2U6|A0A7I2V2U6_HUMAN,tr|A0A7I2YQD4|A0A7I2YQD4_HUMAN,tr|B8ZZU9|B8ZZU9_HUMAN" 4 793.4789 1.04 28062 11641 2 793.478272 397.7467 "Bifunctional methylenetetrahydrofolate dehydrogenase\cyclohydrolase, mitochondrial OS=Homo sapiens OX=9606 GN=MTHFD2 PE=1 SV=2" 8.41 2409.8 - 2.16E+06 - - - -0.7965 - 1.595 0.238 - 128.7 1 2 0 -0.0006 8 0 0 0 2.59E+08 2.48E+08 - - - 2.2067 0.9996 221125_WJC_METTL3_EV_vs_WT_F03.11642.11642.2 0.00278 14-Sep K.ADEGISFR.G "sp|Q06830|PRDX1_HUMAN,tr|A0A0A0MRQ5|A0A0A0MRQ5_HUMAN,tr|A0A0A0MSI0|A0A0A0MSI0_HUMAN" 3 893.4243 0.67 28063 11642 2 893.424271 447.7194 Peroxiredoxin-1 OS=Homo sapiens OX=9606 GN=PRDX1 PE=1 SV=1 4.37 2409.8 - 4.01E+06 - - - -0.028 - 1.838 0.323 - 555.5 1 2 0 0 8 0 0 0 1.03E+09 1.53E+09 - - - 3.2624 0.9993 221125_WJC_METTL3_EV_vs_WT_F03.11647.11647.2 0.00125 22-Jul R.VFANNADQQLVK[136.11].K sp|Q5JVF3|PCID2_HUMAN 1 1353.7132 0.83 28068 11647 2 1353.713297 677.8639 PCI domain-containing protein 2 OS=Homo sapiens OX=9606 GN=PCID2 PE=1 SV=2 5.81 2410.2 - 265736 - - - 0.0613 - 1.512 0.356 - 97.1 1 2 0 0.0001 12 0 0 0 5.11E+06 6.15E+06 - - - 2.7582 0.9997 221125_WJC_METTL3_EV_vs_WT_F03.11650.11650.2 0.00896 14-Sep K.ADEGISFR[166.11].G "sp|Q06830|PRDX1_HUMAN,tr|A0A0A0MRQ5|A0A0A0MRQ5_HUMAN,tr|A0A0A0MSI0|A0A0A0MSI0_HUMAN" 3 903.4326 0.69 28069 11650 2 903.431841 452.7236 Peroxiredoxin-1 OS=Homo sapiens OX=9606 GN=PRDX1 PE=1 SV=1 4.37 2410.6 - 1.29E+07 - - - -0.8025 - 2.048 0.36 - 493 1 2 0 -0.0007 8 0 0 0 1.07E+09 1.54E+09 - - - 3.8618 0.97 221125_WJC_METTL3_EV_vs_WT_F03.11652.11652.2 0.00985 14-Sep R.PGFSIADK.K "sp|P62913|RL11_HUMAN,tr|Q5VVC8|Q5VVC8_HUMAN" 2 833.4283 1.41 28071 11652 2 833.428596 417.7214 60S ribosomal protein L11 OS=Homo sapiens OX=9606 GN=RPL11 PE=1 SV=2 6.26 2410.7 - 2.20E+06 - - - 0.3324 - 1.854 0.289 - 244.5 1 1 0 0.0003 8 0 0 0 6.21E+07 4.41E+07 - - - 3.0374 0.9888 221125_WJC_METTL3_EV_vs_WT_F03.11653.11653.2 0.00023 16-Sep S.YVAFTDTER.L "sp|P48741|HSP77_HUMAN,sp|P54652|HSP72_HUMAN,sp|P0DMV8|HS71A_HUMAN,sp|P34931|HS71L_HUMAN,sp|P11142|HSP7C_HUMAN,sp|P0DMV9|HS71B_HUMAN,sp|P17066|HSP76_HUMAN,tr|E9PQQ4|E9PQQ4_HUMAN,tr|E9PNE6|E9PNE6_HUMAN,tr|E9PKE3|E9PKE3_HUMAN,tr|E9PLF4|E9PLF4_HUMAN,tr|Q53FA3|Q53FA3_HUMAN,tr|E9PI65|E9PI65_HUMAN,tr|E9PK54|E9PK54_HUMAN,tr|E9PN25|E9PN25_HUMAN,tr|E9PPY6|E9PPY6_HUMAN,tr|E9PQK7|E9PQK7_HUMAN,tr|A0A0G2JIW1|A0A0G2JIW1_HUMAN" 18 1100.5138 0.12 28072 11653 2 1100.51422 551.2642 Putative heat shock 70 kDa protein 7 OS=Homo sapiens OX=9606 GN=HSPA7 PE=5 SV=2 4.37 2410.8 - 1.32E+06 - - - 0.3462 - 1.727 0.488 - 265.2 1 1 0 0.0004 9 0 0 0 2.54E+07 2.16E+08 - - - 4.226 0.9935 221125_WJC_METTL3_EV_vs_WT_F03.11654.11654.2 0.0995 14-Sep R.SLTQSYLR.E "sp|P52948|NUP98_HUMAN,tr|H7C3P6|H7C3P6_HUMAN" 2 966.5134 1.13 28073 11654 2 966.512621 484.264 Nuclear pore complex protein Nup98-Nup96 OS=Homo sapiens OX=9606 GN=NUP98 PE=1 SV=4 8.46 2410.9 - 1.21E+06 - - - -0.8525 - 1.334 0.148 - 237.5 1 2 0 -0.0008 8 0 0 0 7.46E+07 6.62E+07 - - - 1.003 0.9998 221125_WJC_METTL3_EV_vs_WT_F03.11657.11657.2 3.28E-05 18-Aug R.FYTEDSPGLK.V "sp|P60468|SC61B_HUMAN,tr|S4R3B5|S4R3B5_HUMAN" 2 1155.5448 1.35 28075 11657 2 1155.544496 578.7797 Protein transport protein Sec61 subunit beta OS=Homo sapiens OX=9606 GN=SEC61B PE=1 SV=2 4.37 2411.2 - 4.42E+06 - - - -0.2674 - 1.663 0.491 - 160.7 1 2 0 -0.0003 10 0 0 0 7.47E+07 5.54E+07 - - - 4.0872 0.995 221125_WJC_METTL3_EV_vs_WT_F03.11660.11660.2 0.136 12-Jun R.FSGVPDR.F "sp|A0A075B6R9|KVD24_HUMAN,sp|A0A0C4DH68|KV224_HUMAN,sp|A2NJV5|KV229_HUMAN,sp|A0A075B6S2|KVD29_HUMAN,sp|A0A0A0MRZ7|KVD26_HUMAN" 5 776.3817 4.84 28077 11660 2 776.381611 389.1981 Probable non-functional immunoglobulin kappa variable 2D-24 OS=Homo sapiens OX=9606 GN=IGKV2D-24 PE=1 SV=1 5.84 2411.6 - 619142 - - - -0.1185 - 1.279 0.173 - 109.7 1 2 0 -0.0001 7 0 0 0 5.54E+07 1.15E+07 - - - 1.0985 0.9994 221125_WJC_METTL3_EV_vs_WT_F03.11664.11664.2 0.0939 14-Sep R.LLDEEISR[166.11].V sp|Q96PU8|QKI_HUMAN 1 983.5163 2.52 28079 11664 2 983.515341 492.7654 Protein quaking OS=Homo sapiens OX=9606 GN=QKI PE=1 SV=1 4.14 2412.1 - 2.24E+06 - - - -0.971 - 1.881 0.284 - 213.1 1 2 0 -0.001 8 0 0 0 1.66E+08 6.58E+07 - - - 3.0438 0.9986 221125_WJC_METTL3_EV_vs_WT_F03.11665.11665.2 0.000332 16-Oct K.LDHVVTIIK.G "sp|Q99873|ANM1_HUMAN,tr|E9PQ98|E9PQ98_HUMAN,tr|E9PKG1|E9PKG1_HUMAN,tr|E9PNR9|E9PNR9_HUMAN,tr|H0YDE4|H0YDE4_HUMAN,tr|E9PIX6|E9PIX6_HUMAN" 6 1036.6281 1.68 28080 11665 2 1036.631264 519.3213 Protein arginine N-methyltransferase 1 OS=Homo sapiens OX=9606 GN=PRMT1 PE=1 SV=3 6.74 2412.2 - 1.16E+06 - - - 3.0705 - 2.103 0.324 - 274.7 1 2 0 0.0032 9 0 0 0 1.08E+08 6.42E+07 - - - 3.5837 0.9996 221125_WJC_METTL3_EV_vs_WT_F03.11666.11666.2 0.00477 16-Sep R.QINDIQLSR[166.11].D "sp|Q13347|EIF3I_HUMAN,tr|A0A7I2YQT9|A0A7I2YQT9_HUMAN,tr|A0A7I2V613|A0A7I2V613_HUMAN,tr|A0A7I2V3N2|A0A7I2V3N2_HUMAN,tr|A0A7I2YQU2|A0A7I2YQU2_HUMAN,tr|A0A7I2YQI6|A0A7I2YQI6_HUMAN,tr|A0A7I2YQF8|A0A7I2YQF8_HUMAN,tr|Q5TFK1|Q5TFK1_HUMAN,tr|A0A7I2V3U3|A0A7I2V3U3_HUMAN,tr|A0A7I2V607|A0A7I2V607_HUMAN,tr|A0A7I2V640|A0A7I2V640_HUMAN,tr|A0A7P0MRT9|A0A7P0MRT9_HUMAN,tr|A0A7I2V3K6|A0A7I2V3K6_HUMAN,tr|A0A7I2V4S8|A0A7I2V4S8_HUMAN,tr|A0A7I2V5V8|A0A7I2V5V8_HUMAN,tr|A0A7I2V2M3|A0A7I2V2M3_HUMAN,tr|A0A7I2V4C2|A0A7I2V4C2_HUMAN,tr|A0A7I2YQP9|A0A7I2YQP9_HUMAN,tr|A0A7I2YQI2|A0A7I2YQI2_HUMAN,tr|A0A7I2YQC8|A0A7I2YQC8_HUMAN,tr|A0A7I2V685|A0A7I2V685_HUMAN" 21 1095.5912 1.44 28081 11666 2 1095.591985 548.8029 Eukaryotic translation initiation factor 3 subunit I OS=Homo sapiens OX=9606 GN=EIF3I PE=1 SV=1 5.84 2412.2 - 5.30E+06 - - - 0.7238 - 1.814 0.367 - 398.6 1 2 0 0.0008 9 0 0 0 1.83E+08 1.27E+08 - - - 3.4743 0.999 221125_WJC_METTL3_EV_vs_WT_F03.11671.11671.2 0.0346 16-Sep K.GLLETTVQK[136.11].V sp|O43290|SNUT1_HUMAN 1 995.5743 2.01 28084 11671 2 995.576005 498.7944 U4\U6.U5 tri-snRNP-associated protein 1 OS=Homo sapiens OX=9606 GN=SART1 PE=1 SV=1 6 2412.9 - 1.10E+06 - - - 1.7518 - 1.811 0.299 - 239.6 1 2 0 0.0017 9 0 0 0 1.20E+08 6.00E+07 - - - 2.967 0.8862 221125_WJC_METTL3_EV_vs_WT_F03.11675.11675.2 0.334 14-Jul R.LTDELQVK[136.11].E "tr|A0A590UJ28|A0A590UJ28_HUMAN,tr|A0A590UK05|A0A590UK05_HUMAN,tr|A0A590UKA6|A0A590UKA6_HUMAN,tr|A0A590UKA3|A0A590UKA3_HUMAN,tr|A0A590UJL9|A0A590UJL9_HUMAN,tr|A0A590UJI4|A0A590UJI4_HUMAN,tr|A0A590UJ77|A0A590UJ77_HUMAN,tr|A0A590UJC1|A0A590UJC1_HUMAN,tr|A0A590UJ83|A0A590UJ83_HUMAN,tr|A0A590UJC6|A0A590UJC6_HUMAN,tr|A0A2U3TZI4|A0A2U3TZI4_HUMAN,tr|A0A590UK19|A0A590UK19_HUMAN,tr|A0A590UJW7|A0A590UJW7_HUMAN,tr|A0A590UJ69|A0A590UJ69_HUMAN,tr|A0A590UK35|A0A590UK35_HUMAN,tr|A0A590UJA8|A0A590UJA8_HUMAN" 16 952.5321 1.88 28086 11675 2 952.534921 477.2733 Coiled-coil domain-containing protein 30 OS=Homo sapiens OX=9606 GN=CCDC30 PE=4 SV=1 4.37 2413.3 - 2.27E+06 - - - 3.0015 - 1.254 0.032 - 122.3 1 2 0 0.0029 8 0 0 0 1.82E+08 9.72E+07 - - - -0.0409 0.9996 221125_WJC_METTL3_EV_vs_WT_F03.11682.11682.2 0.0903 14-Aug R.LESLNIQR.E sp|Q14152|EIF3A_HUMAN 1 971.54 1.29 28091 11682 2 971.539881 486.7773 Eukaryotic translation initiation factor 3 subunit A OS=Homo sapiens OX=9606 GN=EIF3A PE=1 SV=1 6 2414.1 - 5.06E+06 - - - -0.1163 - 1.901 0.307 - 191.2 1 2 0 -0.0001 8 0 0 0 2.73E+08 2.12E+08 - - - 3.2459 0.9987 221125_WJC_METTL3_EV_vs_WT_F03.11684.11684.2 0.0203 14-Jun K.SALEEFSK.M "sp|Q8TAQ2|SMRC2_HUMAN,tr|F8VXC8|F8VXC8_HUMAN" 2 909.4444 3.03 28093 11684 2 909.444671 455.7295 SWI\SNF complex subunit SMARCC2 OS=Homo sapiens OX=9606 GN=SMARCC2 PE=1 SV=1 4.53 2414.2 - 3.05E+06 - - - 0.3387 - 1.491 0.263 - 145 1 2 0 0.0003 8 0 0 0 1.53E+08 5.05E+07 - - - 2.1881 0.9889 221125_WJC_METTL3_EV_vs_WT_F03.11685.11685.2 1.82 16-May K.GLLETTVQK.V sp|O43290|SNUT1_HUMAN 1 987.5601 2.01 28094 11685 2 987.560387 494.7873 U4\U6.U5 tri-snRNP-associated protein 1 OS=Homo sapiens OX=9606 GN=SART1 PE=1 SV=1 6 2414.3 - 3.10E+06 - - - 0.3301 - 1.265 0.174 - 73.2 9 2 0 0.0003 9 0 0 0 1.20E+08 6.00E+07 - - - 0.5799 0.9997 221125_WJC_METTL3_EV_vs_WT_F03.11691.11691.2 0.0174 16-Oct K.FLSDEENLK.L "sp|Q03393|PTPS_HUMAN,tr|E9PKY8|E9PKY8_HUMAN,tr|E9PJM0|E9PJM0_HUMAN" 3 1093.5292 2.64 28098 11691 2 1093.529973 547.7719 6-pyruvoyl tetrahydrobiopterin synthase OS=Homo sapiens OX=9606 GN=PTS PE=1 SV=1 4.14 2415 - 6.31E+06 - - - 0.748 - 1.734 0.442 - 238.2 1 2 0 0.0008 9 0 0 0 2.56E+08 9.73E+07 - - - 3.8978 0.9062 221125_WJC_METTL3_EV_vs_WT_F03.11693.11693.2 0.00498 16-Aug K.FLSDEENLK[136.11].L "sp|Q03393|PTPS_HUMAN,tr|E9PKY8|E9PKY8_HUMAN,tr|E9PJM0|E9PJM0_HUMAN" 3 1101.5434 2.61 28100 11693 2 1101.546841 551.779 6-pyruvoyl tetrahydrobiopterin synthase OS=Homo sapiens OX=9606 GN=PTS PE=1 SV=1 4.14 2415.2 - 2.42E+06 - - - 3.1647 - 1.449 0.008 - 152.4 1 2 0 0.0035 9 0 0 0 2.54E+08 9.73E+07 - - - 0.172 0.9735 221125_WJC_METTL3_EV_vs_WT_F03.11698.11698.2 0.294 14-Jul R.AVFSNLQR[166.11].K "sp|Q14774|HLX_HUMAN,tr|F8VWZ5|F8VWZ5_HUMAN" 2 943.5115 0.67 28103 11698 2 943.511328 472.763 H2.0-like homeobox protein OS=Homo sapiens OX=9606 GN=HLX PE=1 SV=3 9.79 2415.8 - 6.42E+06 - - - -0.1664 - 1.358 0.001 - 182.9 1 2 0 -0.0002 8 0 0 0 1.45E+08 2.15E+08 - - - -0.0287 0.9994 221125_WJC_METTL3_EV_vs_WT_F03.11703.11703.2 0.0018 16-Aug K.LDHVVTIIK[136.11].G "sp|Q99873|ANM1_HUMAN,tr|E9PQ98|E9PQ98_HUMAN,tr|E9PKG1|E9PKG1_HUMAN,tr|E9PNR9|E9PNR9_HUMAN,tr|H0YDE4|H0YDE4_HUMAN,tr|E9PIX6|E9PIX6_HUMAN" 6 1044.6423 1.67 28106 11703 2 1044.643005 523.3284 Protein arginine N-methyltransferase 1 OS=Homo sapiens OX=9606 GN=PRMT1 PE=1 SV=3 6.74 2416.4 - 2.46E+06 - - - 0.6931 - 1.591 0.361 - 148 1 2 0 0.0007 9 0 0 0 1.08E+08 6.49E+07 - - - 3.0505 0.9995 221125_WJC_METTL3_EV_vs_WT_F03.11704.11704.2 0.0137 20-Dec K.LVLVGDGGTGK[136.11].T "sp|P62826|RAN_HUMAN,tr|H0YFC6|H0YFC6_HUMAN,tr|B5MDF5|B5MDF5_HUMAN,tr|J3KQE5|J3KQE5_HUMAN,tr|F5H018|F5H018_HUMAN" 5 1022.5852 0.85 28107 11704 2 1022.584796 512.2999 GTP-binding nuclear protein Ran OS=Homo sapiens OX=9606 GN=RAN PE=1 SV=3 5.84 2416.4 - 4.81E+06 - - - -0.356 - 2.342 0.239 - 482.5 1 2 0 -0.0004 11 0 0 0 1.02E+09 1.20E+09 - - - 3.1083 0.9999 221125_WJC_METTL3_EV_vs_WT_F03.11705.11705.2 1.16E-05 20-Dec R.LPSALTATAC[160.03]K.S "sp|Q92615|LAR4B_HUMAN,tr|A0A087X183|A0A087X183_HUMAN,tr|H0Y641|H0Y641_HUMAN,tr|H0Y4V9|H0Y4V9_HUMAN" 4 1131.5958 1.14 28108 11705 2 1131.59705 566.8052 La-related protein 4B OS=Homo sapiens OX=9606 GN=LARP4B PE=1 SV=3 8.22 2416.5 - 2.04E+06 - - - 1.1091 - 2.611 0.542 - 457.2 1 2 0 0.0013 11 0 0 0 4.07E+08 3.58E+08 - - - 5.6401 0.9996 221125_WJC_METTL3_EV_vs_WT_F03.11711.11711.2 0.0146 16-Sep K.QELETELER.L sp|Q8TBA6|GOGA5_HUMAN 1 1145.5564 2.81 28110 11711 2 1145.557858 573.7855 Golgin subfamily A member 5 OS=Homo sapiens OX=9606 GN=GOLGA5 PE=1 SV=3 4.09 2417.3 - 1.86E+06 - - - 1.2448 - 1.869 0.409 - 310.7 1 2 0 0.0014 9 0 0 0 6.73E+07 2.40E+07 - - - 3.8708 0.9909 221125_WJC_METTL3_EV_vs_WT_F03.11712.11712.2 0.00934 22-Aug K.VLVASATMDTAR.F "sp|O60231|DHX16_HUMAN,tr|A0A140T947|A0A140T947_HUMAN,tr|A0A140T9T4|A0A140T9T4_HUMAN,tr|Q5SQH5|Q5SQH5_HUMAN,tr|A0A140T8Y5|A0A140T8Y5_HUMAN" 5 1233.6387 2.55 28111 11712 2 1233.633481 617.8266 Pre-mRNA-splicing factor ATP-dependent RNA helicase DHX16 OS=Homo sapiens OX=9606 GN=DHX16 PE=1 SV=2 5.81 2417.4 - 342116 - - - -4.2484 - 1.569 0.315 - 130.9 1 2 0 -0.0052 12 0 0 0 1.06E+07 4.14E+06 - - - 2.5511 0.9966 221125_WJC_METTL3_EV_vs_WT_F03.11715.11715.2 0.233 14-Jun R.AVFQESIR[166.11].W "sp|O00139|KIF2A_HUMAN,tr|A0A6Q8PFA6|A0A6Q8PFA6_HUMAN,tr|A0A6Q8PGG1|A0A6Q8PGG1_HUMAN,tr|A0A6Q8PGH7|A0A6Q8PGH7_HUMAN,tr|A0A6Q8PG37|A0A6Q8PG37_HUMAN,tr|A0A6Q8PH57|A0A6Q8PH57_HUMAN" 6 958.5112 0.97 28113 11715 2 958.511904 480.2629 Kinesin-like protein KIF2A OS=Homo sapiens OX=9606 GN=KIF2A PE=1 SV=3 6.05 2417.8 - 1.59E+06 - - - 0.7856 - 1.352 0.213 - 148 1 2 0 0.0008 8 0 0 0 4.21E+07 4.33E+07 - - - 1.5235 0.8479 221125_WJC_METTL3_EV_vs_WT_F03.11718.11718.2 0.0201 16-Aug K.ETLTPSELR.D sp|Q9HCY8|S10AE_HUMAN 1 1044.5451 1 28115 11718 2 1044.550713 523.2798 Protein S100-A14 OS=Homo sapiens OX=9606 GN=S100A14 PE=1 SV=1 4.53 2418.1 - 3.01E+06 - - - 5.3363 - 1.575 0.068 - 177.7 1 2 0 0.0056 9 0 0 0 1.05E+08 1.04E+08 - - - 0.8557 0.9997 221125_WJC_METTL3_EV_vs_WT_F03.11720.11720.2 0.000166 20-Sep K.LVSESSDVLPK.- sp|P05787|K2C8_HUMAN 1 1172.6289 2.27 28117 11720 2 1172.629985 587.3217 "Keratin, type II cytoskeletal 8 OS=Homo sapiens OX=9606 GN=KRT8 PE=1 SV=7" 4.37 2418.3 - 847999 - - - 0.9517 - 1.73 0.439 - 192.2 1 2 0 0.0011 11 0 0 0 3.08E+08 1.36E+08 - - - 3.7659 0.9997 221125_WJC_METTL3_EV_vs_WT_F03.11725.11725.2 0.00221 20-Oct R.EPDTEVITVEK.S "sp|Q9BXK5|B2L13_HUMAN,tr|A0A087WX97|A0A087WX97_HUMAN,tr|A0A087WTL4|A0A087WTL4_HUMAN" 3 1258.6293 0.82 28120 11725 2 1258.629351 630.3219 Bcl-2-like protein 13 OS=Homo sapiens OX=9606 GN=BCL2L13 PE=1 SV=1 4 2418.9 - 695875 - - - 0.0699 - 2.036 0.364 - 443.8 1 2 0 0.0001 11 0 0 0 3.78E+07 4.62E+07 - - - 3.6529 0.9994 221125_WJC_METTL3_EV_vs_WT_F03.11727.11727.2 0.0328 14-Aug K.SALEEFSK[136.11].M "sp|Q8TAQ2|SMRC2_HUMAN,tr|F8VXC8|F8VXC8_HUMAN" 2 917.4586 3.03 28122 11727 2 917.457571 459.7366 SWI\SNF complex subunit SMARCC2 OS=Homo sapiens OX=9606 GN=SMARCC2 PE=1 SV=1 4.53 2419.1 - 1.63E+06 - - - -1.0812 - 1.698 0.332 - 208.9 1 2 0 -0.001 8 0 0 0 1.50E+08 4.97E+07 - - - 3.0896 0.9993 221125_WJC_METTL3_EV_vs_WT_F03.11733.11733.2 0.0211 20-Aug K.LVSESSDVLPK[136.11].- sp|P05787|K2C8_HUMAN 1 1180.6431 2.28 28126 11733 2 1180.644414 591.3288 "Keratin, type II cytoskeletal 8 OS=Homo sapiens OX=9606 GN=KRT8 PE=1 SV=7" 4.37 2419.8 - 543723 - - - 1.1392 - 1.524 0.381 - 132 1 2 0 0.0013 11 0 0 0 3.10E+08 1.36E+08 - - - 2.9945 0.9993 221125_WJC_METTL3_EV_vs_WT_F03.11737.11737.2 0.0158 16-Sep K.R[166.11]LLGQIVDR[166.11].C sp|Q96I24|FUBP3_HUMAN 1 1088.6569 1.78 28128 11737 2 1088.655792 545.3357 Far upstream element-binding protein 3 OS=Homo sapiens OX=9606 GN=FUBP3 PE=1 SV=2 9.6 2420.5 - 998871 - - - -1.0334 - 1.767 0.293 - 154.2 1 2 0 -0.0011 9 0 0 0 7.17E+07 4.04E+07 - - - 2.8517 0.9973 221125_WJC_METTL3_EV_vs_WT_F03.11739.11739.2 0.326 14-Aug R.ELQDAFSR.G "sp|Q99848|EBP2_HUMAN,tr|H7C2Q8|H7C2Q8_HUMAN" 2 964.4614 2.14 28129 11739 2 964.462943 483.238 Probable rRNA-processing protein EBP2 OS=Homo sapiens OX=9606 GN=EBNA1BP2 PE=1 SV=2 4.37 2420.7 - 900874 - - - 1.5895 - 1.396 0.27 - 125.6 1 2 0 0.0015 8 0 0 0 5.26E+07 2.46E+07 - - - 2.0409 0.9997 221125_WJC_METTL3_EV_vs_WT_F03.11741.11741.2 0.00557 18-Nov K.IMQEYQLEQK[136.11].D sp|Q9P032|NDUF4_HUMAN 1 1316.6526 1.64 28131 11741 2 1316.652972 659.3336 NADH dehydrogenase [ubiquinone] 1 alpha subcomplex assembly factor 4 OS=Homo sapiens OX=9606 GN=NDUFAF4 PE=1 SV=1 4.53 2420.9 - 1.31E+06 - - - 0.2916 - 1.732 0.413 - 329.8 1 2 0 0.0004 10 0 0 0 1.15E+08 7.02E+07 - - - 3.6245 0.9998 221125_WJC_METTL3_EV_vs_WT_F03.11743.11743.2 0.000689 20-Sep R.EPDTEVITVEK[136.11].S "sp|Q9BXK5|B2L13_HUMAN,tr|A0A087WX97|A0A087WX97_HUMAN,tr|A0A087WTL4|A0A087WTL4_HUMAN" 3 1266.6435 0.9 28133 11743 2 1266.643804 634.329 Bcl-2-like protein 13 OS=Homo sapiens OX=9606 GN=BCL2L13 PE=1 SV=1 4 2421.2 - 268075 - - - 0.2692 - 2.079 0.423 - 409.7 1 2 0 0.0003 11 0 0 0 4.42E+07 4.90E+07 - - - 4.1451 0.9972 221125_WJC_METTL3_EV_vs_WT_F03.11746.11746.2 0.295 14-Jul R.EDIASLTR[166.11].E "sp|Q9Y605|MOFA1_HUMAN,tr|A0A087WTY9|A0A087WTY9_HUMAN" 2 913.4744 2.91 28134 11746 2 913.47371 457.7445 MORF4 family-associated protein 1 OS=Homo sapiens OX=9606 GN=MRFAP1 PE=1 SV=1 4.37 2421.6 - 3.15E+06 - - - -0.7893 - 1.592 0.156 - 195 1 2 0 -0.0007 8 0 0 0 2.47E+08 8.49E+07 - - - 1.5954 0.8576 221125_WJC_METTL3_EV_vs_WT_F03.11747.11747.2 0.324 16-May R.LYIC[160.03]AGC[160.03]GR[166.11].D sp|Q7L3S4|ZN771_HUMAN 1 1078.4927 0.89 28135 11747 2 1078.496786 540.2536 Zinc finger protein 771 OS=Homo sapiens OX=9606 GN=ZNF771 PE=1 SV=1 8.06 2421.7 - 678932 - - - 3.7506 - 0.93 0.178 - 67.4 1 2 0 0.004 9 0 0 0 2.44E+07 2.74E+07 - - - 0.1445 0.9999 221125_WJC_METTL3_EV_vs_WT_F03.11748.11748.2 1.13E-05 20-Nov K.LTDNGTEFSVK.V "sp|P52732|KIF11_HUMAN,tr|A0A7I2YQY4|A0A7I2YQY4_HUMAN,tr|A0A7I2V3A9|A0A7I2V3A9_HUMAN,tr|A0A7I2V3V3|A0A7I2V3V3_HUMAN" 4 1209.5877 4.28 28136 11748 2 1209.588209 605.8011 Kinesin-like protein KIF11 OS=Homo sapiens OX=9606 GN=KIF11 PE=1 SV=2 4.37 2421.8 - 4.07E+06 - - - 0.3935 - 2.239 0.552 - 351.7 1 2 0 0.0005 11 0 0 0 1.64E+09 3.83E+08 - - - 5.2984 0.9999 221125_WJC_METTL3_EV_vs_WT_F03.11750.11750.2 2.68E-05 20-Nov R.LPSALTATAC[160.03]K[136.11].S "sp|Q92615|LAR4B_HUMAN,tr|A0A087X183|A0A087X183_HUMAN,tr|H0Y641|H0Y641_HUMAN,tr|H0Y4V9|H0Y4V9_HUMAN" 4 1139.61 1.22 28137 11750 2 1139.610312 570.8123 La-related protein 4B OS=Homo sapiens OX=9606 GN=LARP4B PE=1 SV=3 8.22 2422 - 3.44E+06 - - - 0.2782 - 2.274 0.473 - 554.5 1 2 0 0.0003 11 0 0 0 4.42E+08 3.61E+08 - - - 4.7569 0.9998 221125_WJC_METTL3_EV_vs_WT_F03.11751.11751.2 0.0107 16-Oct R.GPLVNASLR.A "sp|O14744|ANM5_HUMAN,tr|H0YJ77|H0YJ77_HUMAN,tr|H0YJX6|H0YJX6_HUMAN" 3 925.5345 1.66 28138 11751 2 925.534302 463.7745 Protein arginine N-methyltransferase 5 OS=Homo sapiens OX=9606 GN=PRMT5 PE=1 SV=4 9.75 2422.1 - 1.62E+06 - - - -0.2301 - 2.105 0.356 - 485.7 1 2 0 -0.0002 9 0 0 0 1.54E+08 9.25E+07 - - - 3.8237 0.9987 221125_WJC_METTL3_EV_vs_WT_F03.11752.11752.2 0.0253 16-Aug R.AEWEPPEAR.A sp|Q8IYS1|P20D2_HUMAN 1 1083.4985 28.43 28139 11752 2 1083.499706 542.7565 Xaa-Arg dipeptidase OS=Homo sapiens OX=9606 GN=PM20D2 PE=1 SV=2 4.25 2422.2 - 514183 - - - 1.0918 - 1.387 0.332 - 217.4 1 2 0 0.0012 9 0 0 0 1.82E+07 6.39E+05 - - - 2.4392 0.9974 221125_WJC_METTL3_EV_vs_WT_F03.11755.11755.2 0.0393 14-Jul R.EDIASLTR.E "sp|Q9Y605|MOFA1_HUMAN,tr|A0A087WTY9|A0A087WTY9_HUMAN" 2 903.4662 2.89 28140 11755 2 903.465764 452.7404 MORF4 family-associated protein 1 OS=Homo sapiens OX=9606 GN=MRFAP1 PE=1 SV=1 4.37 2422.6 - 9.74E+06 - - - -0.4394 - 1.588 0.157 - 220.3 1 2 0 -0.0004 8 0 0 0 2.53E+08 8.76E+07 - - - 1.5953 0.9923 221125_WJC_METTL3_EV_vs_WT_F03.11762.11762.2 0.261 16-Sep K.SLSEYNNFK[136.11].S "sp|P24928|RPB1_HUMAN,tr|A0A6Q8PGB0|A0A6Q8PGB0_HUMAN" 2 1108.528 1.26 28145 11762 2 1108.527237 555.2713 DNA-directed RNA polymerase II subunit RPB1 OS=Homo sapiens OX=9606 GN=POLR2A PE=1 SV=2 5.72 2423.4 - 1.05E+06 - - - -0.7235 - 1.143 0.193 - 198.6 1 2 0 -0.0008 9 0 0 0 2.86E+07 2.26E+07 - - - 0.8529 0.9926 221125_WJC_METTL3_EV_vs_WT_F03.11767.11767.2 0.0017 16-Aug K.MSTEEIIQR[166.11].T "sp|P17980|PRS6A_HUMAN,tr|R4GNH3|R4GNH3_HUMAN,tr|E9PMD8|E9PMD8_HUMAN,tr|E9PKD5|E9PKD5_HUMAN,tr|E9PLG2|E9PLG2_HUMAN,tr|E9PM69|E9PM69_HUMAN,tr|E9PN50|E9PN50_HUMAN" 7 1115.552 3.05 28147 11767 2 1115.545501 558.7833 26S proteasome regulatory subunit 6A OS=Homo sapiens OX=9606 GN=PSMC3 PE=1 SV=3 4.53 2424 - 850600 - - - -5.8518 - 1.921 0.416 - 300.7 1 2 0 -0.0065 9 0 0 0 2.02E+08 6.62E+07 - - - 4.0002 0.9973 221125_WJC_METTL3_EV_vs_WT_F03.11771.11771.2 0.405 18-Jul K.LELEQTYQAK[136.11].L sp|Q03252|LMNB2_HUMAN 1 1229.6383 1.16 28149 11771 2 1229.636082 615.8264 Lamin-B2 OS=Homo sapiens OX=9606 GN=LMNB2 PE=1 SV=4 4.53 2424.5 - 641794 - - - -1.8184 - 1.751 0.198 - 141.5 1 2 0 -0.0022 10 0 0 0 8.01E+07 6.90E+07 - - - 2.0664 0.9997 221125_WJC_METTL3_EV_vs_WT_F03.11773.11773.2 0.0352 12-Jul R.FYDLSSK[136.11].Y "sp|Q9UNM6|PSD13_HUMAN,tr|J3KNQ3|J3KNQ3_HUMAN,tr|E9PL38|E9PL38_HUMAN,tr|H0YD73|H0YD73_HUMAN,tr|A0A087WUL9|A0A087WUL9_HUMAN" 5 866.4265 0.69 28150 11773 2 866.426321 434.2205 26S proteasome non-ATPase regulatory subunit 13 OS=Homo sapiens OX=9606 GN=PSMD13 PE=1 SV=2 5.83 2424.8 - 3.51E+06 - - - -0.2458 - 1.716 0.408 - 148.7 1 2 0 -0.0002 7 0 0 0 5.68E+07 8.23E+07 - - - 3.7654 0.9998 221125_WJC_METTL3_EV_vs_WT_F03.11774.11774.2 0.00246 16-Sep K.GSDFDC[160.03]ELR[166.11].L "sp|P61978|HNRPK_HUMAN,tr|Q5T6W2|Q5T6W2_HUMAN" 2 1107.453 1.24 28151 11774 2 1107.453309 554.7338 Heterogeneous nuclear ribonucleoprotein K OS=Homo sapiens OX=9606 GN=HNRNPK PE=1 SV=1 4.03 2424.8 - 1.32E+06 - - - 0.2393 - 1.686 0.503 - 357.7 1 2 0 0.0003 9 0 0 0 2.56E+08 2.06E+08 - - - 4.2673 0.9997 221125_WJC_METTL3_EV_vs_WT_F03.11781.11781.2 0.00122 16-Aug R.GGDLMAYDR.R "sp|P61978|HNRPK_HUMAN,tr|Q5T6W2|Q5T6W2_HUMAN" 2 996.4335 1.42 28156 11781 2 996.434963 499.224 Heterogeneous nuclear ribonucleoprotein K OS=Homo sapiens OX=9606 GN=HNRNPK PE=1 SV=1 4.21 2425.5 - 8.97E+06 - - - 1.4883 - 1.783 0.48 - 324.1 1 2 0 0.0015 9 0 0 0 2.27E+08 1.60E+08 - - - 4.2589 0.9998 221125_WJC_METTL3_EV_vs_WT_F03.11782.11782.2 0.000316 20-Sep R.AVVGYEDGTIR[166.11].L "sp|Q13685|AAMP_HUMAN,tr|C9JG97|C9JG97_HUMAN,tr|C9JEH3|C9JEH3_HUMAN,tr|C9JTS3|C9JTS3_HUMAN" 4 1188.6014 0.87 28157 11782 2 1188.601806 595.308 Angio-associated migratory cell protein OS=Homo sapiens OX=9606 GN=AAMP PE=1 SV=2 4.37 2425.5 - 3.66E+06 - - - 0.3231 - 1.989 0.422 - 263.2 1 2 0 0.0004 11 0 0 0 1.08E+08 1.25E+08 - - - 4.018 0.9998 221125_WJC_METTL3_EV_vs_WT_F03.11783.11783.2 0.0127 16-Aug K.GSDFDC[160.03]ELR.L "sp|P61978|HNRPK_HUMAN,tr|Q5T6W2|Q5T6W2_HUMAN" 2 1097.4448 1.24 28158 11783 2 1097.445075 549.7297 Heterogeneous nuclear ribonucleoprotein K OS=Homo sapiens OX=9606 GN=HNRNPK PE=1 SV=1 4.03 2425.6 - 1.67E+06 - - - 0.2743 - 1.803 0.497 - 383 1 2 0 0.0003 9 0 0 0 2.56E+08 2.06E+08 - - - 4.4171 0.9996 221125_WJC_METTL3_EV_vs_WT_F03.11784.11784.2 0.0595 14-Oct R.FHEQFIVR.E "sp|Q06787|FMR1_HUMAN,tr|A0A087WY29|A0A087WY29_HUMAN,tr|R9WNI0|R9WNI0_HUMAN,tr|A8MQB8|A8MQB8_HUMAN,tr|A0A087WWR6|A0A087WWR6_HUMAN,tr|A0A087WXI3|A0A087WXI3_HUMAN,tr|Q8IXW7|Q8IXW7_HUMAN,tr|G3V0J0|G3V0J0_HUMAN" 8 1074.5611 1.31 28159 11784 2 1074.561296 538.2878 Synaptic functional regulator FMR1 OS=Homo sapiens OX=9606 GN=FMR1 PE=1 SV=1 6.75 2425.7 - 1.27E+06 - - - 0.2159 - 1.775 0.333 - 516.6 1 2 0 0.0002 8 0 0 0 6.54E+07 5.01E+07 - - - 3.231 0.8597 221125_WJC_METTL3_EV_vs_WT_F03.11793.11793.2 1.72 16-Jul K.SPQLSLSPR.P "sp|O95785|WIZ_HUMAN,tr|A0A669KBG4|A0A669KBG4_HUMAN,tr|A0A2R8YFV2|A0A2R8YFV2_HUMAN,tr|A0A669KAV7|A0A669KAV7_HUMAN,tr|M0QXA7|M0QXA7_HUMAN,tr|A0A669KBH9|A0A669KBH9_HUMAN,tr|B9EGQ5|B9EGQ5_HUMAN" 7 983.54 1 28166 11793 2 983.539452 492.7773 Protein Wiz OS=Homo sapiens OX=9606 GN=WIZ PE=1 SV=2 9.47 2426.6 - 712437 - - - -0.5511 - 1.621 0.155 - 114 1 1 0 -0.0005 9 0 0 0 2.33E+07 2.33E+07 - - - 1.5831 0.9999 221125_WJC_METTL3_EV_vs_WT_F03.11799.11799.2 5.07E-05 20-Dec K.GEENLMDAQVK[136.11].A "sp|P50990|TCPQ_HUMAN,tr|H7C4C8|H7C4C8_HUMAN" 2 1240.5849 0.36 28169 11799 2 1240.584148 621.2997 T-complex protein 1 subunit theta OS=Homo sapiens OX=9606 GN=CCT8 PE=1 SV=4 4.14 2427.5 - 777881 - - - -0.6078 - 2.327 0.51 - 556.9 1 2 0 -0.0008 11 0 0 0 9.69E+07 2.67E+08 - - - 5.0924 0.9988 221125_WJC_METTL3_EV_vs_WT_F03.11802.11802.2 0.0134 18-Jun K.VVNGPEILNK[136.11].Y "sp|P46459|NSF_HUMAN,tr|I3L0N3|I3L0N3_HUMAN" 2 1089.6274 0.39 28172 11802 2 1089.627186 545.821 Vesicle-fusing ATPase OS=Homo sapiens OX=9606 GN=NSF PE=1 SV=3 5.97 2427.8 - 457108 - - - -0.1588 - 1.272 0.336 - 83.8 1 2 0 -0.0002 10 0 0 0 2.01E+07 5.14E+07 - - - 2.1942 0.9915 221125_WJC_METTL3_EV_vs_WT_F03.11805.11805.2 2.70E-05 18-Aug K.EYSGFAGVSR.P "sp|Q9NYF8|BCLF1_HUMAN,tr|H0YF63|H0YF63_HUMAN,tr|E9PK91|E9PK91_HUMAN,tr|H0YF14|H0YF14_HUMAN" 4 1071.4985 2.18 28173 11805 2 1071.498129 536.7565 Bcl-2-associated transcription factor 1 OS=Homo sapiens OX=9606 GN=BCLAF1 PE=1 SV=2 6.1 2428.2 - 5.11E+06 - - - -0.3677 - 1.585 0.577 - 284.1 1 1 0 -0.0004 10 0 0 0 2.80E+09 1.28E+09 - - - 4.5882 0.9991 221125_WJC_METTL3_EV_vs_WT_F03.11806.11806.2 0.00994 14-Aug K.TDPVDIYK.S "sp|P46940|IQGA1_HUMAN,tr|H0YLE8|H0YLE8_HUMAN,tr|A0A0J9YXZ5|A0A0J9YXZ5_HUMAN" 3 949.4757 0.86 28174 11806 2 949.475427 475.7451 Ras GTPase-activating-like protein IQGAP1 OS=Homo sapiens OX=9606 GN=IQGAP1 PE=1 SV=1 4.21 2428.3 - 709552 - - - -0.2486 - 1.333 0.348 - 176.3 1 2 0 -0.0002 8 0 0 0 6.82E+07 7.94E+07 - - - 2.4781 0.9956 221125_WJC_METTL3_EV_vs_WT_F03.11807.11807.2 0.256 12-Jul R.LWDVQSK[136.11].Q "sp|Q9BV38|WDR18_HUMAN,tr|U3KQC1|U3KQC1_HUMAN,tr|U3KQK3|U3KQK3_HUMAN,tr|A0A0A0MQU0|A0A0A0MQU0_HUMAN,tr|K7EIR0|K7EIR0_HUMAN" 5 882.4691 1.3 28175 11807 2 882.468541 442.2418 WD repeat-containing protein 18 OS=Homo sapiens OX=9606 GN=WDR18 PE=1 SV=2 5.84 2428.3 - 3.56E+06 - - - -0.5972 - 1.327 0.174 - 151.8 1 2 0 -0.0005 7 0 0 0 1.64E+08 1.27E+08 - - - 1.2224 0.9995 221125_WJC_METTL3_EV_vs_WT_F03.11812.11812.2 0.00364 16-Oct R.QLDSIVGER.G "sp|P48668|K2C6C_HUMAN,sp|P13647|K2C5_HUMAN,sp|P02538|K2C6A_HUMAN,tr|F8W0C6|F8W0C6_HUMAN" 4 1015.5298 162.56 28178 11812 2 1015.528208 508.7722 "Keratin, type II cytoskeletal 6C OS=Homo sapiens OX=9606 GN=KRT6C PE=1 SV=3" 4.37 2429 - 1.31E+08 - - - -1.5913 - 1.867 0.364 - 569.9 1 2 0 -0.0016 9 0 0 0 1.95E+10 1.20E+08 - - - 3.5352 0.9988 221125_WJC_METTL3_EV_vs_WT_F03.11813.11813.3 0.0302 Nov-40 R.IIGLKPEGVPR.L "sp|P54709|AT1B3_HUMAN,tr|C9JA36|C9JA36_HUMAN,tr|H7C4L9|H7C4L9_HUMAN" 3 1177.7183 1.24 28179 11813 3 1177.717583 393.58 Sodium\potassium-transporting ATPase subunit beta-3 OS=Homo sapiens OX=9606 GN=ATP1B3 PE=1 SV=1 8.75 2429 - 4.02E+06 - - - -0.6029 - 2.063 0.231 - 114 1 2 0 -0.0007 11 0 0 0 2.31E+08 1.86E+08 - - - 3.1724 0.9999 221125_WJC_METTL3_EV_vs_WT_F03.11814.11814.3 0.00104 Oct-40 R.IIGLK[136.11]PEGVPR[166.11].L "sp|P54709|AT1B3_HUMAN,tr|C9JA36|C9JA36_HUMAN,tr|H7C4L9|H7C4L9_HUMAN" 3 1195.7408 1.24 28180 11814 3 1195.740415 399.5875 Sodium\potassium-transporting ATPase subunit beta-3 OS=Homo sapiens OX=9606 GN=ATP1B3 PE=1 SV=1 8.75 2429.1 - 3.57E+06 - - - -0.291 - 2.103 0.392 - 88.2 1 2 0 -0.0003 11 0 0 0 2.31E+08 1.86E+08 - - - 5.0221 0.9997 221125_WJC_METTL3_EV_vs_WT_F03.11818.11818.2 0.0354 14-Oct R.QELSFAAR[166.11].S "sp|P49327|FAS_HUMAN,tr|A0A0U1RQF0|A0A0U1RQF0_HUMAN" 2 930.4799 0.65 28182 11818 2 930.479066 466.2472 Fatty acid synthase OS=Homo sapiens OX=9606 GN=FASN PE=1 SV=3 6 2429.5 - 2.71E+06 - - - -0.8426 - 2.048 0.358 - 417.2 1 2 0 -0.0008 8 0 0 0 8.35E+07 1.28E+08 - - - 3.847 0.9658 221125_WJC_METTL3_EV_vs_WT_F03.11820.11820.2 0.0356 14-Aug K.LLHHLSDL.A "sp|Q86U44|MTA70_HUMAN,tr|B4E349|B4E349_HUMAN,tr|F5H6D8|F5H6D8_HUMAN,tr|H0YFV6|H0YFV6_HUMAN,tr|B4DTN4|B4DTN4_HUMAN" 5 946.5236 - 28184 11820 2 946.523102 474.2691 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 5.97 2429.6 - 3.20E+06 - - - -0.543 - 1.76 0.291 - 142.4 1 1 0 -0.0005 8 0 0 0 - - - - - 2.8951 0.9639 221125_WJC_METTL3_EV_vs_WT_F03.11822.11822.2 0.00296 14-Aug R.YPDGIISK[136.11].P sp|Q86U44|MTA70_HUMAN 1 899.4844 -1 28186 11822 2 899.48498 450.7495 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 5.83 2429.8 - 1.49E+06 - - - 0.6637 - 1.524 0.356 - 176.6 1 1 0 0.0006 8 0 0 0 0.00E+00 0.00E+00 - - - 2.941 0.9936 221125_WJC_METTL3_EV_vs_WT_F03.11827.11827.2 0.365 14-Aug K.NVTLGVPR[166.11].L "sp|P24928|RPB1_HUMAN,tr|A0A6Q8PGB0|A0A6Q8PGB0_HUMAN" 2 864.5057 1.15 28190 11827 2 864.504376 433.2601 DNA-directed RNA polymerase II subunit RPB1 OS=Homo sapiens OX=9606 GN=POLR2A PE=1 SV=2 9.75 2430.4 - 882370 - - - -1.498 - 1.483 0.137 - 256.8 1 2 0 -0.0013 8 0 0 0 4.17E+07 3.62E+07 - - - 1.241 0.9999 221125_WJC_METTL3_EV_vs_WT_F03.11829.11829.3 0.000978 16/40 K.SDLLGK[136.11]PLGPR[166.11].T "sp|Q8IY67|RAVR1_HUMAN,tr|E9PAU2|E9PAU2_HUMAN,tr|A0A087WZ13|A0A087WZ13_HUMAN" 3 1169.6887 0.86 28191 11829 3 1169.687772 390.9035 Ribonucleoprotein PTB-binding 1 OS=Homo sapiens OX=9606 GN=RAVER1 PE=1 SV=1 8.46 2430.7 - 729055 - - - -0.8173 - 2.435 0.392 - 324.4 1 2 0 -0.001 11 0 0 0 5.67E+07 6.55E+07 - - - 5.4383 0.9909 221125_WJC_METTL3_EV_vs_WT_F03.11830.11830.2 0.0167 18-Nov K.LDSSIISEGK[136.11].L "sp|P30260|CDC27_HUMAN,tr|I3L328|I3L328_HUMAN,tr|G5EA36|G5EA36_HUMAN" 3 1055.559 5.81 28192 11830 2 1055.563713 528.7868 Cell division cycle protein 27 homolog OS=Homo sapiens OX=9606 GN=CDC27 PE=1 SV=2 4.37 2430.8 - 668116 - - - 4.4602 - 1.892 0.257 - 252 1 2 0 0.0047 10 0 0 0 2.39E+07 4.11E+06 - - - 2.7176 0.9998 221125_WJC_METTL3_EV_vs_WT_F03.11832.11832.2 0.000433 18-Sep R.DTALTIAADK[136.11].G "sp|O75179|ANR17_HUMAN,sp|Q8IWZ3|ANKH1_HUMAN,tr|E9PDP5|E9PDP5_HUMAN,tr|H0YM23|H0YM23_HUMAN,tr|H3BLS9|H3BLS9_HUMAN,tr|H0YLQ3|H0YLQ3_HUMAN,tr|H7C2F5|H7C2F5_HUMAN" 7 1025.5484 23.99 28194 11832 2 1025.547404 513.7815 Ankyrin repeat domain-containing protein 17 OS=Homo sapiens OX=9606 GN=ANKRD17 PE=1 SV=3 4.21 2430.9 - 4.62E+06 - - - -1.0102 - 1.902 0.45 - 345.3 1 2 0 -0.001 10 0 0 0 2.94E+09 1.23E+08 - - - 4.1589 0.9993 221125_WJC_METTL3_EV_vs_WT_F03.11833.11833.2 0.00199 14-Aug K.TDPVDIYK[136.11].S "sp|P46940|IQGA1_HUMAN,tr|H0YLE8|H0YLE8_HUMAN,tr|A0A0J9YXZ5|A0A0J9YXZ5_HUMAN" 3 957.4899 0.88 28195 11833 2 957.489208 479.7522 Ras GTPase-activating-like protein IQGAP1 OS=Homo sapiens OX=9606 GN=IQGAP1 PE=1 SV=1 4.21 2430.9 - 1.88E+06 - - - -0.6841 - 1.398 0.358 - 299.7 1 2 0 -0.0007 8 0 0 0 6.81E+07 7.78E+07 - - - 2.6955 0.9905 221125_WJC_METTL3_EV_vs_WT_F03.11835.11835.2 0.291 18-Sep K.LDPSPQTIYK.W "sp|P78344|IF4G2_HUMAN,tr|H0Y3P2|H0Y3P2_HUMAN,tr|D3DQV9|D3DQV9_HUMAN" 3 1160.6077 1.78 28197 11835 2 1160.610297 581.3111 Eukaryotic translation initiation factor 4 gamma 2 OS=Homo sapiens OX=9606 GN=EIF4G2 PE=1 SV=1 5.83 2431.2 - 894199 - - - 2.2032 - 1.558 0.144 - 122.4 1 2 0 0.0026 10 0 0 0 3.73E+07 2.09E+07 - - - 1.3415 0.9999 221125_WJC_METTL3_EV_vs_WT_F03.11836.11836.2 9.21E-07 13/20 K.YQAVTATLEEK.R "sp|P40429|RL13A_HUMAN,sp|Q6NVV1|R13P3_HUMAN,tr|M0QYS1|M0QYS1_HUMAN,tr|Q8J015|Q8J015_HUMAN,tr|A0A7I2V2L9|A0A7I2V2L9_HUMAN,tr|A0A7I2V5L3|A0A7I2V5L3_HUMAN" 6 1251.6347 0.9 28198 11836 2 1251.633644 626.8246 60S ribosomal protein L13a OS=Homo sapiens OX=9606 GN=RPL13A PE=1 SV=2 4.53 2431.3 - 679809 - - - -0.8301 - 2.347 0.531 - 419.2 1 2 0 -0.001 11 0 0 0 1.75E+08 1.95E+08 - - - 5.2706 0.9938 221125_WJC_METTL3_EV_vs_WT_F03.11840.11840.2 0.11 14-Jul K.NVTLGVPR.L "sp|P24928|RPB1_HUMAN,tr|A0A6Q8PGB0|A0A6Q8PGB0_HUMAN" 2 854.4974 1.16 28200 11840 2 854.497086 428.256 DNA-directed RNA polymerase II subunit RPB1 OS=Homo sapiens OX=9606 GN=POLR2A PE=1 SV=2 9.75 2431.8 - 1.44E+06 - - - -0.3686 - 1.432 0.113 - 191.1 1 2 0 -0.0003 8 0 0 0 4.22E+07 3.63E+07 - - - 0.9585 1 221125_WJC_METTL3_EV_vs_WT_F03.11841.11841.2 1.48E-07 20-Dec K.GEENLMDAQVK.A "sp|P50990|TCPQ_HUMAN,tr|H7C4C8|H7C4C8_HUMAN" 2 1232.5707 0.36 28201 11841 2 1232.564956 617.2926 T-complex protein 1 subunit theta OS=Homo sapiens OX=9606 GN=CCT8 PE=1 SV=4 4.14 2431.8 - 2.24E+06 - - - -4.6618 - 2.568 0.581 - 705 1 2 0 -0.0057 11 0 0 0 9.70E+07 2.68E+08 - - - 5.8818 0.9506 221125_WJC_METTL3_EV_vs_WT_F03.11846.11846.2 1.01E-05 22-Oct K.NVYATTVGTPYK.G "sp|Q13439|GOGA4_HUMAN,tr|H0Y6I0|H0Y6I0_HUMAN" 2 1312.6663 3.04 28204 11846 2 1313.664563 657.3404 Golgin subfamily A member 4 OS=Homo sapiens OX=9606 GN=GOLGA4 PE=1 SV=1 8.5 2432.4 - 486054 - - - 760.472 - 2.183 0.507 - 228.1 1 2 0 0.9982 12 0 0 0 2.86E+07 9.40E+06 - - - 4.5264 0.9999 221125_WJC_METTL3_EV_vs_WT_F03.11847.11847.3 0.134 15/40 K.SDLLGKPLGPR.T "sp|Q8IY67|RAVR1_HUMAN,tr|E9PAU2|E9PAU2_HUMAN,tr|A0A087WZ13|A0A087WZ13_HUMAN" 3 1151.6663 0.86 28205 11847 3 1151.666494 384.896 Ribonucleoprotein PTB-binding 1 OS=Homo sapiens OX=9606 GN=RAVER1 PE=1 SV=1 8.46 2432.6 - 612568 - - - 0.2049 - 2.605 0.394 - 290 1 2 0 0.0002 11 0 0 0 5.67E+07 6.55E+07 - - - 5.6525 0.9996 221125_WJC_METTL3_EV_vs_WT_F03.11850.11850.2 0.00164 12-Jun R.DYSQYYR.T "sp|Q04695|K1C17_HUMAN,tr|K7EPJ9|K7EPJ9_HUMAN,tr|F5GWP8|F5GWP8_HUMAN" 3 993.4192 2090.46 28206 11850 2 993.418813 497.7169 "Keratin, type I cytoskeletal 17 OS=Homo sapiens OX=9606 GN=KRT17 PE=1 SV=2" 5.83 2433 - 1.36E+07 - - - -0.4006 - 1.383 0.442 - 150.8 1 2 0 -0.0004 7 0 0 0 1.32E+09 6.32E+05 - - - 3.3329 0.9544 221125_WJC_METTL3_EV_vs_WT_F03.11852.11852.2 0.0779 18-Sep W.VQFSSEEGLR.N "sp|Q9GZT3|SLIRP_HUMAN,tr|H0YJW7|H0YJW7_HUMAN,tr|A0A087WUN7|A0A087WUN7_HUMAN,tr|G3V2S9|G3V2S9_HUMAN,tr|H0YJ40|H0YJ40_HUMAN,tr|G3V4X6|G3V4X6_HUMAN" 6 1150.5619 5.59 28208 11852 2 1150.560841 576.2882 "SRA stem-loop-interacting RNA-binding protein, mitochondrial OS=Homo sapiens OX=9606 GN=SLIRP PE=1 SV=1" 4.53 2433.2 - 479192 - - - -0.8787 - 1.796 0.274 - 185.8 1 1 0 -0.001 10 0 0 0 1.76E+07 3.14E+06 - - - 2.6989 0.9993 221125_WJC_METTL3_EV_vs_WT_F03.11861.11861.2 0.000109 16-Aug K.SDTLPLATR.Y "sp|Q15269|PWP2_HUMAN,tr|A0A0B4J2E5|A0A0B4J2E5_HUMAN,tr|C9J544|C9J544_HUMAN" 3 972.524 0.52 28212 11861 2 972.522928 487.2693 Periodic tryptophan protein 2 homolog OS=Homo sapiens OX=9606 GN=PWP2 PE=2 SV=2 5.55 2434.4 - 1.64E+06 - - - -1.1126 - 1.935 0.263 - 197.2 1 2 0 -0.0011 9 0 0 0 5.75E+07 1.10E+08 - - - 2.8929 0.9988 221125_WJC_METTL3_EV_vs_WT_F03.11864.11864.2 0.00848 16-Jul K.ELLADQNLK[136.11].F sp|Q14684|RRP1B_HUMAN 1 1050.5801 1.07 28215 11864 2 1050.578876 526.2973 Ribosomal RNA processing protein 1 homolog B OS=Homo sapiens OX=9606 GN=RRP1B PE=1 SV=3 4.37 2434.6 - 1.44E+06 - - - -1.1413 - 1.55 0.283 - 131.2 1 2 0 -0.0012 9 0 0 0 5.03E+07 4.72E+07 - - - 2.3988 0.9953 221125_WJC_METTL3_EV_vs_WT_F03.11869.11869.2 0.0792 16-Sep K.ELLADQNLK.F sp|Q14684|RRP1B_HUMAN 1 1042.5659 1.09 28217 11869 2 1042.563492 522.2902 Ribosomal RNA processing protein 1 homolog B OS=Homo sapiens OX=9606 GN=RRP1B PE=1 SV=3 4.37 2435.2 - 2.00E+06 - - - -2.2857 - 1.549 0.214 - 201.1 1 2 0 -0.0024 9 0 0 0 5.14E+07 4.72E+07 - - - 1.8869 0.9679 221125_WJC_METTL3_EV_vs_WT_F03.11870.11870.2 0.00471 16-Sep R.SLYNLGGSK.R "sp|P13647|K2C5_HUMAN,tr|F8VV57|F8VV57_HUMAN" 2 937.4869 292.89 28218 11870 2 938.489192 469.7507 "Keratin, type II cytoskeletal 5 OS=Homo sapiens OX=9606 GN=KRT5 PE=1 SV=3" 8.31 2435.4 - 612120 - - - 1069.1307 - 1.64 0.356 - 251 1 2 0 1.0023 9 0 0 0 1.91E+09 6.52E+06 - - - 2.7869 0.9969 221125_WJC_METTL3_EV_vs_WT_F03.11873.11873.2 0.183 14-Aug K.QLTQLINK.K "sp|Q15643|TRIPB_HUMAN,tr|H0YJ97|H0YJ97_HUMAN" 2 956.5655 1.03 28219 11873 2 956.566471 479.29 Thyroid receptor-interacting protein 11 OS=Homo sapiens OX=9606 GN=TRIP11 PE=1 SV=3 8.75 2435.7 - 2.54E+06 - - - 1.035 - 1.598 0.165 - 248.5 1 2 0 0.001 8 0 0 0 1.14E+08 1.11E+08 - - - 1.6731 0.9998 221125_WJC_METTL3_EV_vs_WT_F03.11876.11876.2 0.000185 16-Sep K.DAFADAVQR[166.11].A "sp|Q92945|FUBP2_HUMAN,tr|M0R0I5|M0R0I5_HUMAN,tr|M0R0C6|M0R0C6_HUMAN,tr|A0A087WTP3|A0A087WTP3_HUMAN" 4 1001.4806 1.08 28221 11876 2 1001.480343 501.7476 Far upstream element-binding protein 2 OS=Homo sapiens OX=9606 GN=KHSRP PE=1 SV=4 4.21 2436 - 4.96E+06 - - - -0.2357 - 2.019 0.426 - 277.7 1 2 0 -0.0002 9 0 0 0 2.87E+08 2.65E+08 - - - 4.22 0.9997 221125_WJC_METTL3_EV_vs_WT_F03.11879.11879.2 0.00555 14-Sep R.ALAAFLK[136.11]K[136.11].S "sp|P39019|RS19_HUMAN,tr|M0R140|M0R140_HUMAN,tr|M0R2L9|M0R2L9_HUMAN,tr|M0QYF7|M0QYF7_HUMAN" 4 876.5768 1.02 28224 11879 2 876.576068 439.2957 40S ribosomal protein S19 OS=Homo sapiens OX=9606 GN=RPS19 PE=1 SV=2 10 2436.2 - 2.02E+06 - - - -0.8054 - 1.637 0.408 - 275 1 2 0 -0.0007 8 0 0 0 3.99E+08 3.93E+08 - - - 3.5407 0.9928 221125_WJC_METTL3_EV_vs_WT_F03.11880.11880.2 0.369 14-Jul R.ALAAFLKK.S "sp|P39019|RS19_HUMAN,tr|M0R140|M0R140_HUMAN,tr|M0R2L9|M0R2L9_HUMAN,tr|M0QYF7|M0QYF7_HUMAN" 4 860.5484 1.02 28225 11880 2 860.546495 431.2815 40S ribosomal protein S19 OS=Homo sapiens OX=9606 GN=RPS19 PE=1 SV=2 10 2436.4 - 1.19E+06 - - - -2.1835 - 1.446 0.2 - 168.4 2 2 0 -0.0019 8 0 0 0 3.99E+08 3.93E+08 - - - 1.4954 0.999 221125_WJC_METTL3_EV_vs_WT_F03.11885.11885.2 0.0154 14-Jul R.LGFTDVNK.L "sp|Q92544|TM9S4_HUMAN,tr|A0A0C4DFM1|A0A0C4DFM1_HUMAN" 2 892.4654 0.82 28228 11885 2 892.463672 447.24 Transmembrane 9 superfamily member 4 OS=Homo sapiens OX=9606 GN=TM9SF4 PE=1 SV=2 5.84 2436.9 - 2.83E+06 - - - -1.9721 - 1.535 0.377 - 128.6 1 2 0 -0.0018 8 0 0 0 9.90E+07 1.21E+08 - - - 3.1174 0.819 221125_WJC_METTL3_EV_vs_WT_F03.11886.11886.2 0.136 12-Jul A.LAAFLK[136.11]K[136.11].S "sp|P39019|RS19_HUMAN,tr|M0R140|M0R140_HUMAN,tr|M0R2L9|M0R2L9_HUMAN,tr|M0QYF7|M0QYF7_HUMAN" 4 805.5397 1.07 28229 11886 2 805.538947 403.7771 40S ribosomal protein S19 OS=Homo sapiens OX=9606 GN=RPS19 PE=1 SV=2 10 2437 - 2.04E+06 - - - -0.8851 - 1.617 0.117 - 146.1 1 1 0 -0.0007 7 0 0 0 2.34E+08 2.19E+08 - - - 1.4277 0.9979 221125_WJC_METTL3_EV_vs_WT_F03.11887.11887.2 0.0164 12-Jun R.AAC[160.03]LC[160.03]FR[166.11].S "sp|Q8NFP7|NUD10_HUMAN,sp|Q96G61|NUD11_HUMAN,sp|O95989|NUDT3_HUMAN,sp|Q9NZJ9|NUDT4_HUMAN,sp|A0A024RBG1|NUD4B_HUMAN" 5 906.4079 0.75 28230 11887 2 906.406862 454.2113 Diphosphoinositol polyphosphate phosphohydrolase 3-alpha OS=Homo sapiens OX=9606 GN=NUDT10 PE=1 SV=1 8.11 2437.1 - 974510 - - - -1.1981 - 1.174 0.328 - 143.8 1 2 0 -0.0011 7 0 0 0 2.66E+07 3.53E+07 - - - 1.9716 0.9921 221125_WJC_METTL3_EV_vs_WT_F03.11888.11888.2 0.251 20-Aug K.AVPVESPVQKV.- sp|Q8TB61|S35B2_HUMAN 1 1151.655 1.26 28231 11888 2 1151.655869 576.8348 Adenosine 3'-phospho 5'-phosphosulfate transporter 1 OS=Homo sapiens OX=9606 GN=SLC35B2 PE=1 SV=1 6.05 2437.2 - 859508 - - - 0.7337 - 1.292 0.157 - 173.2 1 2 0 0.0008 11 0 0 0 6.28E+07 4.96E+07 - - - 0.8934 0.8905 221125_WJC_METTL3_EV_vs_WT_F03.11893.11893.2 0.0716 12-Sep A.LAAFLKK.S "sp|P39019|RS19_HUMAN,tr|M0R140|M0R140_HUMAN,tr|M0R2L9|M0R2L9_HUMAN,tr|M0QYF7|M0QYF7_HUMAN" 4 789.5113 1.07 28234 11893 2 789.51202 395.7629 40S ribosomal protein S19 OS=Homo sapiens OX=9606 GN=RPS19 PE=1 SV=2 10 2437.9 - 2.31E+06 - - - 0.9626 - 1.858 0.133 - 235.7 1 1 0 0.0008 7 0 0 0 2.34E+08 2.19E+08 - - - 1.986 0.9709 221125_WJC_METTL3_EV_vs_WT_F03.11895.11895.2 0.0174 16-Aug K.EQVPGFTPR.L "sp|P11586|C1TC_HUMAN,tr|F5H2F4|F5H2F4_HUMAN,tr|V9GYY3|V9GYY3_HUMAN" 3 1029.5243 1.64 28236 11895 2 1029.518049 515.7694 "C-1-tetrahydrofolate synthase, cytoplasmic OS=Homo sapiens OX=9606 GN=MTHFD1 PE=1 SV=4" 6.1 2438.1 - 1.05E+06 - - - -6.1145 - 1.627 0.302 - 240.4 1 2 0 -0.0063 9 0 0 0 2.76E+08 1.68E+08 - - - 2.6778 0.9999 221125_WJC_METTL3_EV_vs_WT_F03.11902.11902.2 0.000667 16-Nov K.LNNEYEVIK.S "sp|Q15643|TRIPB_HUMAN,tr|H0YJ97|H0YJ97_HUMAN" 2 1120.5764 1.25 28241 11902 2 1120.576505 561.2955 Thyroid receptor-interacting protein 11 OS=Homo sapiens OX=9606 GN=TRIP11 PE=1 SV=3 4.53 2438.9 - 2.38E+06 - - - 0.058 - 2.383 0.421 - 339.3 1 2 0 0.0001 9 0 0 0 4.53E+08 3.63E+08 - - - 4.6627 0.9931 221125_WJC_METTL3_EV_vs_WT_F03.11903.11903.2 0.379 12-May K.DFSDITK[136.11].K sp|Q9NR30|DDX21_HUMAN 1 832.4058 0.93 28242 11903 2 832.405569 417.2102 Nucleolar RNA helicase 2 OS=Homo sapiens OX=9606 GN=DDX21 PE=1 SV=5 4.21 2439 - 3.81E+06 - - - -0.2763 - 1.109 0.203 - 97.3 1 2 0 -0.0002 7 0 0 0 7.64E+07 8.19E+07 - - - 0.8681 0.9993 221125_WJC_METTL3_EV_vs_WT_F03.11904.11904.2 0.0023 16-Oct K.EQVPGFTPR[166.11].L "sp|P11586|C1TC_HUMAN,tr|F5H2F4|F5H2F4_HUMAN,tr|V9GYY3|V9GYY3_HUMAN" 3 1039.5326 1.66 28243 11904 2 1039.533868 520.7736 "C-1-tetrahydrofolate synthase, cytoplasmic OS=Homo sapiens OX=9606 GN=MTHFD1 PE=1 SV=4" 6.1 2439 - 2.08E+06 - - - 1.2063 - 1.646 0.359 - 410.6 1 2 0 0.0013 9 0 0 0 2.81E+08 1.69E+08 - - - 3.1339 0.9997 221125_WJC_METTL3_EV_vs_WT_F03.11910.11910.2 0.00031 16-Aug K.LNNEYEVIK[136.11].S "sp|Q15643|TRIPB_HUMAN,tr|H0YJ97|H0YJ97_HUMAN" 2 1128.5906 1.24 28247 11910 2 1128.590432 565.3026 Thyroid receptor-interacting protein 11 OS=Homo sapiens OX=9606 GN=TRIP11 PE=1 SV=3 4.53 2439.7 - 4.41E+06 - - - -0.1843 - 1.995 0.341 - 163 1 2 0 -0.0002 9 0 0 0 4.52E+08 3.64E+08 - - - 3.5576 0.9996 221125_WJC_METTL3_EV_vs_WT_F03.11912.11912.2 0.00115 16-Aug R.LTYEIEDEK.R sp|P15924|DESP_HUMAN 1 1138.5394 3.73 28249 11912 2 1138.537685 570.277 Desmoplakin OS=Homo sapiens OX=9606 GN=DSP PE=1 SV=3 4 2439.9 - 758167 - - - -1.4931 - 1.798 0.397 - 211.3 1 2 0 -0.0017 9 0 0 0 9.85E+07 2.64E+07 - - - 3.67 0.9985 221125_WJC_METTL3_EV_vs_WT_F03.11915.11915.2 0.00254 24-Sep K.C[160.03]LATGPGIASTVK.T "sp|O75369|FLNB_HUMAN,tr|E7EN95|E7EN95_HUMAN,tr|A0A804HK76|A0A804HK76_HUMAN,tr|A0A804HL72|A0A804HL72_HUMAN" 4 1273.67 1.28 28252 11915 2 1273.673514 637.8423 Filamin-B OS=Homo sapiens OX=9606 GN=FLNB PE=1 SV=2 8.22 2440.3 - 304699 - - - 2.7409 - 1.961 0.336 - 192.2 1 2 0 0.0035 13 0 0 0 1.11E+07 8.64E+06 - - - 3.25 0.9998 221125_WJC_METTL3_EV_vs_WT_F03.11916.11916.2 0.000324 13/24 K.C[160.03]LATGPGIASTVK[136.11].T "sp|O75369|FLNB_HUMAN,tr|E7EN95|E7EN95_HUMAN,tr|A0A804HK76|A0A804HK76_HUMAN,tr|A0A804HL72|A0A804HL72_HUMAN" 4 1281.6842 1.28 28253 11916 2 1281.683303 641.8494 Filamin-B OS=Homo sapiens OX=9606 GN=FLNB PE=1 SV=2 8.22 2440.4 - 291377 - - - -0.7178 - 2.155 0.41 - 409.1 1 2 0 -0.0009 13 0 0 0 1.11E+07 8.64E+06 - - - 4.0395 0.837 221125_WJC_METTL3_EV_vs_WT_F03.11921.11921.2 0.00641 14-Jul K.GIVEFSGK.P "sp|Q15233|NONO_HUMAN,tr|A0A7I2V535|A0A7I2V535_HUMAN,tr|A0A7I2V4N2|A0A7I2V4N2_HUMAN,tr|A0A7I2V464|A0A7I2V464_HUMAN,tr|A0A7P0MRW0|A0A7P0MRW0_HUMAN,tr|H7C367|H7C367_HUMAN,tr|C9IZL7|C9IZL7_HUMAN,tr|A0A7I2V4J2|A0A7I2V4J2_HUMAN,tr|A0A7I2V5Y7|A0A7I2V5Y7_HUMAN" 9 835.444 0.77 28256 11921 2 835.443735 418.7293 Non-POU domain-containing octamer-binding protein OS=Homo sapiens OX=9606 GN=NONO PE=1 SV=4 6 2441 - 4.64E+06 - - - -0.2801 - 1.441 0.173 - 183.5 1 1 0 -0.0002 8 0 0 0 1.10E+08 1.43E+08 - - - 1.4205 0.9984 221125_WJC_METTL3_EV_vs_WT_F03.11922.11922.2 0.0502 12-Jul R.DALQGFK.L "sp|P08579|RU2B_HUMAN,sp|P09012|SNRPA_HUMAN,tr|M0R268|M0R268_HUMAN" 3 777.4021 1.11 28257 11922 2 777.403058 389.7083 U2 small nuclear ribonucleoprotein B'' OS=Homo sapiens OX=9606 GN=SNRPB2 PE=1 SV=1 5.84 2441.1 - 3.69E+06 - - - 1.2272 - 1.353 0.314 - 234.5 1 2 0 0.001 7 0 0 0 1.45E+08 1.31E+08 - - - 2.3178 0.9997 221125_WJC_METTL3_EV_vs_WT_F03.11923.11923.2 0.00117 16-Sep K.TVINYDVAR.D "sp|Q86XP3|DDX42_HUMAN,tr|A0A0A0MSJ0|A0A0A0MSJ0_HUMAN" 2 1049.5506 1.08 28258 11923 2 1049.55122 525.7826 ATP-dependent RNA helicase DDX42 OS=Homo sapiens OX=9606 GN=DDX42 PE=1 SV=1 5.5 2441.1 - 3.66E+06 - - - 0.6298 - 1.548 0.439 - 280 1 2 0 0.0007 9 0 0 0 1.02E+08 9.46E+07 - - - 3.5474 0.9967 221125_WJC_METTL3_EV_vs_WT_F03.11929.11929.2 1.66 12-Jul K.TAWLDGK[136.11].H "sp|P23284|PPIB_HUMAN,tr|A0A7P0Z497|A0A7P0Z497_HUMAN,tr|A0A7P0TB45|A0A7P0TB45_HUMAN" 3 797.4163 0.37 28262 11929 2 797.41607 399.7154 Peptidyl-prolyl cis-trans isomerase B OS=Homo sapiens OX=9606 GN=PPIB PE=1 SV=2 5.5 2441.8 - 3.19E+06 - - - -0.2934 - 1.398 0.177 - 222.3 1 2 0 -0.0002 7 0 0 0 7.39E+07 2.01E+08 - - - 1.4099 0.9998 221125_WJC_METTL3_EV_vs_WT_F03.11934.11934.2 0.0025 16-Dec K.KLEPVVFEK.V "sp|Q8WU79|SMAP2_HUMAN,tr|A0A087WV97|A0A087WV97_HUMAN,tr|X6RCC3|X6RCC3_HUMAN" 3 1087.6277 2.35 28265 11934 2 1087.629335 544.8211 Stromal membrane-associated protein 2 OS=Homo sapiens OX=9606 GN=SMAP2 PE=1 SV=1 6.14 2442.4 - 2.77E+06 - - - 1.4601 - 2.425 0.44 - 542.4 1 2 0 0.0016 9 0 0 0 1.08E+08 4.59E+07 - - - 4.8531 0.9993 221125_WJC_METTL3_EV_vs_WT_F03.11935.11935.2 0.0428 16-Sep K.K[136.11]LEPVVFEK[136.11].V "sp|Q8WU79|SMAP2_HUMAN,tr|A0A087WV97|A0A087WV97_HUMAN,tr|X6RCC3|X6RCC3_HUMAN" 3 1103.6561 2.55 28266 11935 2 1103.65714 552.8353 Stromal membrane-associated protein 2 OS=Homo sapiens OX=9606 GN=SMAP2 PE=1 SV=1 6.14 2442.5 - 1.86E+06 - - - 0.8997 - 1.871 0.288 - 265.9 1 2 0 0.001 9 0 0 0 1.17E+08 4.59E+07 - - - 2.9803 0.9946 221125_WJC_METTL3_EV_vs_WT_F03.11942.11942.2 0.305 18-Sep K.VVNGPEILNK.Y "sp|P46459|NSF_HUMAN,tr|I3L0N3|I3L0N3_HUMAN" 2 1081.6132 0.56 28271 11942 2 1081.613609 541.8139 Vesicle-fusing ATPase OS=Homo sapiens OX=9606 GN=NSF PE=1 SV=3 5.97 2443.2 - 1.70E+06 - - - 0.416 - 1.4 0.151 - 196.3 1 2 0 0.0004 10 0 0 0 3.63E+07 6.51E+07 - - - 1.0953 0.9998 221125_WJC_METTL3_EV_vs_WT_F03.11943.11943.2 0.000821 20-Aug K.FLESYATDNEK[136.11].M sp|Q9BZI7|REN3B_HUMAN 1 1323.6074 1.06 28272 11943 2 1323.606536 662.811 Regulator of nonsense transcripts 3B OS=Homo sapiens OX=9606 GN=UPF3B PE=1 SV=1 4.14 2443.3 - 420850 - - - -0.6618 - 1.684 0.542 - 154.3 1 2 0 -0.0009 11 0 0 0 5.05E+07 4.75E+07 - - - 4.4538 0.9998 221125_WJC_METTL3_EV_vs_WT_F03.11945.11945.2 0.000192 22-Oct R.AQVQEFC[160.03]DYGTK[136.11].E "sp|Q86U44|MTA70_HUMAN,tr|H0YFV6|H0YFV6_HUMAN" 2 1452.6435 0.01 28274 11945 2 1452.645064 727.329 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 4.37 2443.6 - 186592 - - - 1.0904 - 2.329 0.512 - 302.5 1 2 0 0.0016 12 0 0 0 8.86E+05 1.02E+08 - - - 5.0466 0.9903 221125_WJC_METTL3_EV_vs_WT_F03.11948.11948.3 0.26 Sep-40 R.LWDHATMTEVK[136.11].S sp|Q9Y3F4|STRAP_HUMAN 1 1337.6529 0.77 28275 11948 3 1337.652656 446.8916 Serine-threonine kinase receptor-associated protein OS=Homo sapiens OX=9606 GN=STRAP PE=1 SV=1 5.32 2444 - 2.08E+06 - - - -0.1989 - 1.683 0.162 - 117.3 1 2 0 -0.0003 11 0 0 0 4.87E+07 6.34E+07 - - - 1.8249 0.9999 221125_WJC_METTL3_EV_vs_WT_F03.11950.11950.2 0.00176 20-Nov R.AIMYEETTYSK[136.11].K "sp|P52701|MSH6_HUMAN,tr|A0A494C0M1|A0A494C0M1_HUMAN,tr|A0A087WWJ1|A0A087WWJ1_HUMAN" 3 1342.6206 0.49 28277 11950 2 1342.621097 672.3176 DNA mismatch repair protein Msh6 OS=Homo sapiens OX=9606 GN=MSH6 PE=1 SV=2 4.53 2444.2 - 511077 - - - 0.356 - 2.068 0.498 - 216.4 1 2 0 0.0005 11 0 0 0 4.40E+06 9.01E+06 - - - 4.6847 0.9998 221125_WJC_METTL3_EV_vs_WT_F03.11955.11955.3 0.000441 Oct-40 R.LWDHATMTEVK.S sp|Q9Y3F4|STRAP_HUMAN 1 1329.6387 0.78 28280 11955 3 1329.637965 444.2202 Serine-threonine kinase receptor-associated protein OS=Homo sapiens OX=9606 GN=STRAP PE=1 SV=1 5.32 2444.8 - 1.75E+06 - - - -0.5693 - 1.885 0.378 - 148.5 1 2 0 -0.0008 11 0 0 0 4.93E+07 6.34E+07 - - - 4.555 0.9171 221125_WJC_METTL3_EV_vs_WT_F03.11956.11956.2 2.69 22-Aug R.GGTILAPTVSAK.T "sp|Q7L014|DDX46_HUMAN,tr|A0A0C4DG89|A0A0C4DG89_HUMAN" 2 1113.6394 3.08 28281 11956 2 1113.636792 557.827 Probable ATP-dependent RNA helicase DDX46 OS=Homo sapiens OX=9606 GN=DDX46 PE=1 SV=2 8.75 2444.8 - 1.15E+06 - - - -2.3185 - 1.34 0.034 - 145.8 3 2 0 -0.0026 12 0 0 0 7.44E+07 2.42E+07 - - - -0.1518 0.9975 221125_WJC_METTL3_EV_vs_WT_F03.11961.11961.2 0.233 12-Jun K.VLEFNC[160.03]R[166.11].F "sp|P22102|PUR2_HUMAN,tr|F8WD69|F8WD69_HUMAN" 2 946.457 0.57 28284 11961 2 946.456509 474.2358 Trifunctional purine biosynthetic protein adenosine-3 OS=Homo sapiens OX=9606 GN=GART PE=1 SV=1 5.97 2445.5 - 1.75E+06 - - - -0.5262 - 1.265 0.25 - 118.3 1 2 0 -0.0005 7 0 0 0 2.42E+07 4.22E+07 - - - 1.6322 0.9038 221125_WJC_METTL3_EV_vs_WT_F03.11963.11963.2 0.122 12-May T.FPDENFK[136.11].L "sp|P45877|PPIC_HUMAN,sp|P23284|PPIB_HUMAN,tr|A0A7P0Z497|A0A7P0Z497_HUMAN,tr|A0A7P0TB45|A0A7P0TB45_HUMAN" 4 903.4218 0.5 28286 11963 2 903.421758 452.7182 Peptidyl-prolyl cis-trans isomerase C OS=Homo sapiens OX=9606 GN=PPIC PE=1 SV=1 4.37 2445.6 - 1.55E+06 - - - -0.0277 - 1.217 0.301 - 58.8 1 1 0 0 7 0 0 0 2.12E+07 4.27E+07 - - - 1.8864 0.8181 221125_WJC_METTL3_EV_vs_WT_F03.11964.11964.2 0.248 16-Jul K.FTYLGSQDR[166.11].A "sp|Q7Z2W4|ZCCHV_HUMAN,tr|C9J6P4|C9J6P4_HUMAN,tr|A0A7P0T8C6|A0A7P0T8C6_HUMAN" 3 1095.5224 0.57 28287 11964 2 1095.528598 548.7685 Zinc finger CCCH-type antiviral protein 1 OS=Homo sapiens OX=9606 GN=ZC3HAV1 PE=1 SV=3 5.84 2445.7 - 1.34E+06 - - - 5.6174 - 1.28 0.147 - 172.1 1 2 0 0.0062 9 0 0 0 1.69E+07 2.99E+07 - - - 0.839 0.9574 221125_WJC_METTL3_EV_vs_WT_F03.11965.11965.2 3.43 12-May R.DYSQYYR.T "sp|Q04695|K1C17_HUMAN,tr|K7EPJ9|K7EPJ9_HUMAN,tr|F5GWP8|F5GWP8_HUMAN" 3 993.4192 2090.46 28288 11965 2 993.419468 497.7169 "Keratin, type I cytoskeletal 17 OS=Homo sapiens OX=9606 GN=KRT17 PE=1 SV=2" 5.83 2445.7 - 3.52E+06 - - - 0.2587 - 1.091 0.068 - 98.4 2 2 0 0.0003 7 0 0 0 1.32E+09 6.32E+05 - - - -0.3153 0.9999 221125_WJC_METTL3_EV_vs_WT_F03.11966.11966.2 0.000154 20-Dec R.LWDHATMTEVK[136.11].S sp|Q9Y3F4|STRAP_HUMAN 1 1337.6529 0.55 28289 11966 2 1337.651901 669.8337 Serine-threonine kinase receptor-associated protein OS=Homo sapiens OX=9606 GN=STRAP PE=1 SV=1 5.32 2445.9 - 258220 - - - -0.7633 - 2.347 0.519 - 557.4 1 2 0 -0.001 11 0 0 0 2.42E+06 4.41E+06 - - - 5.182 0.9999 221125_WJC_METTL3_EV_vs_WT_F03.11967.11967.2 4.55E-05 24-Oct K.LDNQAVTEEELSR[166.11].A sp|O43822|CF410_HUMAN 1 1512.7295 1.02 28290 11967 2 1512.729853 757.372 Cilia- and flagella-associated protein 410 OS=Homo sapiens OX=9606 GN=CFAP410 PE=1 SV=1 4 2446 - 223386 - - - 0.2096 - 2.115 0.513 - 248.1 1 2 0 0.0003 13 0 0 0 3.41E+06 3.33E+06 - - - 4.7524 0.999 221125_WJC_METTL3_EV_vs_WT_F03.11971.11971.2 0.0897 14-Aug K.SVFEEEVR.E sp|Q03252|LMNB2_HUMAN 1 993.4767 0.89 28292 11971 2 993.478094 497.7456 Lamin-B2 OS=Homo sapiens OX=9606 GN=LMNB2 PE=1 SV=4 4.25 2446.5 - 3.13E+06 - - - 1.378 - 1.454 0.357 - 245.1 1 2 0 0.0014 8 0 0 0 7.50E+07 8.42E+07 - - - 2.8063 0.9998 221125_WJC_METTL3_EV_vs_WT_F03.11974.11974.2 1.20E-05 16-Aug R.DPYGFGDSR[166.11].D sp|Q9HCD5|NCOA5_HUMAN 1 1022.4333 1.66 28295 11974 2 1022.434152 512.2239 Nuclear receptor coactivator 5 OS=Homo sapiens OX=9606 GN=NCOA5 PE=1 SV=2 4.21 2446.7 - 1.01E+06 - - - 0.8392 - 1.767 0.554 - 253.3 1 2 0 0.0009 9 0 0 0 5.09E+07 3.06E+07 - - - 4.7795 0.9558 221125_WJC_METTL3_EV_vs_WT_F03.11975.11975.2 0.0289 16-Jul R.GAQYQPILR[166.11].D "sp|P26358|DNMT1_HUMAN,tr|A0A7I2V5D0|A0A7I2V5D0_HUMAN,tr|A0A7I2V5F1|A0A7I2V5F1_HUMAN,tr|A0A7I2YQA8|A0A7I2YQA8_HUMAN,tr|A0A7I2YQQ0|A0A7I2YQQ0_HUMAN,tr|K7ENW7|K7ENW7_HUMAN,tr|A0A7I2V490|A0A7I2V490_HUMAN" 7 1054.5799 1 28296 11975 2 1054.585802 528.2972 DNA (cytosine-5)-methyltransferase 1 OS=Homo sapiens OX=9606 GN=DNMT1 PE=1 SV=2 8.75 2446.8 - 766091 - - - 5.5975 - 1.427 0.262 - 211.2 1 2 0 0.0059 9 0 0 0 1.57E+07 1.56E+07 - - - 2.003 0.9922 221125_WJC_METTL3_EV_vs_WT_F03.11978.11978.2 0.444 12-Jun K.DFSDITK.K sp|Q9NR30|DDX21_HUMAN 1 824.3916 0.93 28298 11978 2 824.392118 413.2031 Nucleolar RNA helicase 2 OS=Homo sapiens OX=9606 GN=DDX21 PE=1 SV=5 4.21 2447.2 - 650140 - - - 0.6296 - 1.182 0.177 - 128.6 1 2 0 0.0005 7 0 0 0 7.64E+07 8.19E+07 - - - 0.878 0.9996 221125_WJC_METTL3_EV_vs_WT_F03.11981.11981.2 0.0014 16-Jul R.VIFPTGDSK.V "sp|P24928|RPB1_HUMAN,tr|A0A6Q8PGB0|A0A6Q8PGB0_HUMAN" 2 962.5073 0.82 28300 11981 2 962.507599 482.2609 DNA-directed RNA polymerase II subunit RPB1 OS=Homo sapiens OX=9606 GN=POLR2A PE=1 SV=2 5.81 2447.5 - 1.11E+06 - - - 0.3138 - 1.46 0.426 - 160.7 1 2 0 0.0003 9 0 0 0 3.88E+07 4.72E+07 - - - 3.2822 0.9978 221125_WJC_METTL3_EV_vs_WT_F03.11982.11982.2 0.00558 22-Oct K.LLNDEDQVVVNK[136.11].A "sp|P35222|CTNB1_HUMAN,tr|A0A2R8Y5C3|A0A2R8Y5C3_HUMAN,tr|A0A2R8YCH5|A0A2R8YCH5_HUMAN,tr|A0A2R8Y543|A0A2R8Y543_HUMAN,tr|A0A2R8Y750|A0A2R8Y750_HUMAN,tr|B4DGU4|B4DGU4_HUMAN,tr|A0A2R8Y5A3|A0A2R8Y5A3_HUMAN,tr|A0A2R8Y804|A0A2R8Y804_HUMAN,tr|A0A2R8Y5Z1|A0A2R8Y5Z1_HUMAN,tr|A0A2R8Y7Z0|A0A2R8Y7Z0_HUMAN" 10 1392.734 1.3 28301 11982 2 1392.733927 697.3743 Catenin beta-1 OS=Homo sapiens OX=9606 GN=CTNNB1 PE=1 SV=1 4.03 2447.5 - 961778 - - - -0.0589 - 1.47 0.223 - 195.3 1 2 0 -0.0001 12 0 0 0 1.96E+07 1.51E+07 - - - 1.7017 0.8192 221125_WJC_METTL3_EV_vs_WT_F03.11983.11983.2 0.491 12-Jul K.QFSQYIK[136.11].N "sp|P46777|RL5_HUMAN,tr|A0A2R8Y6J3|A0A2R8Y6J3_HUMAN" 2 920.4847 0.59 28302 11983 2 920.4906 461.2496 60S ribosomal protein L5 OS=Homo sapiens OX=9606 GN=RPL5 PE=1 SV=3 8.59 2447.6 - 894367 - - - 6.3901 - 1.201 0.213 - 205.8 1 2 0 0.0059 7 0 0 0 1.36E+08 2.30E+08 - - - 1.1927 0.9998 221125_WJC_METTL3_EV_vs_WT_F03.11987.11987.2 6.74E-05 20-Nov R.IASPEGQDYLK[136.11].G sp|Q9Y3I0|RTCB_HUMAN 1 1227.6227 1.25 28304 11987 2 1227.623364 614.8186 RNA-splicing ligase RtcB homolog OS=Homo sapiens OX=9606 GN=RTCB PE=1 SV=1 4.37 2448.2 - 6.81E+06 - - - 0.5669 - 2.299 0.404 - 462.1 1 2 0 0.0007 11 0 0 0 2.05E+08 1.64E+08 - - - 4.2768 1 221125_WJC_METTL3_EV_vs_WT_F03.11988.11988.2 3.94E-06 13/22 R.ISVYYNEATGGK[136.11].Y "sp|P07437|TBB5_HUMAN,tr|Q5JP53|Q5JP53_HUMAN" 2 1308.6441 0.7 28305 11988 2 1308.642798 655.3293 Tubulin beta chain OS=Homo sapiens OX=9606 GN=TUBB PE=1 SV=2 6 2448.2 - 1.98E+06 - - - -1.0194 - 2.431 0.617 - 891.1 1 2 0 -0.0013 12 0 0 0 4.24E+08 6.02E+08 - - - 5.935 0.9999 221125_WJC_METTL3_EV_vs_WT_F03.11989.11989.2 4.98E-06 22-Nov R.ISVYYNEATGGK.Y "sp|P07437|TBB5_HUMAN,tr|Q5JP53|Q5JP53_HUMAN" 2 1300.6299 0.7 28306 11989 2 1300.630203 651.3222 Tubulin beta chain OS=Homo sapiens OX=9606 GN=TUBB PE=1 SV=2 6 2448.4 - 1.45E+06 - - - 0.2084 - 2.352 0.524 - 514.2 1 2 0 0.0003 12 0 0 0 4.24E+08 6.02E+08 - - - 5.1615 0.8831 221125_WJC_METTL3_EV_vs_WT_F03.11990.11990.2 1.46 14-Jun R.VYSIDYGR[166.11].R "sp|O15381|NVL_HUMAN,tr|E9PH71|E9PH71_HUMAN,tr|E7EWK7|E7EWK7_HUMAN,tr|E9PGD8|E9PGD8_HUMAN" 4 981.4795 0.33 28307 11990 2 981.483651 491.747 Nuclear valosin-containing protein-like OS=Homo sapiens OX=9606 GN=NVL PE=1 SV=1 5.81 2448.4 - 779511 - - - 4.213 - 1.138 0.165 - 102 2 2 0 0.0041 8 0 0 0 2.33E+07 6.95E+07 - - - 0.5138 0.8828 221125_WJC_METTL3_EV_vs_WT_F03.11991.11991.2 0.0206 20-Jun K.LIEAEDNMNC[160.03]Q.M "sp|P62318|SMD3_HUMAN,tr|H3BT13|H3BT13_HUMAN" 2 1335.5435 - 28308 11991 2 1335.545437 668.779 Small nuclear ribonucleoprotein Sm D3 OS=Homo sapiens OX=9606 GN=SNRPD3 PE=1 SV=1 3.57 2448.6 - 350654 - - - 1.4488 - 1.08 0.39 - 108.8 1 1 0 0.0019 11 0 0 0 - - - - - 2.1291 0.9994 221125_WJC_METTL3_EV_vs_WT_F03.11994.11994.2 0.0254 14-Sep R.TSASIILR.G "sp|P17987|TCPA_HUMAN,tr|F5GZ03|F5GZ03_HUMAN,tr|F5H282|F5H282_HUMAN,tr|E7EQR6|E7EQR6_HUMAN,tr|E7ERF2|E7ERF2_HUMAN" 5 859.5127 0.19 28309 11994 2 859.513408 430.7636 T-complex protein 1 subunit alpha OS=Homo sapiens OX=9606 GN=TCP1 PE=1 SV=1 9.41 2449 - 6.35E+06 - - - 0.8039 - 1.776 0.318 - 377.2 1 2 0 0.0007 8 0 0 0 1.24E+08 6.49E+08 - - - 3.1218 0.8503 221125_WJC_METTL3_EV_vs_WT_F03.11997.11997.2 0.00333 20-Oct M.GLLSNNNQALR.R "sp|Q13283|G3BP1_HUMAN,tr|A0A7I2YQB1|A0A7I2YQB1_HUMAN,tr|A0A7I2V5M7|A0A7I2V5M7_HUMAN,tr|E5RH42|E5RH42_HUMAN,tr|A0A7P0P2U7|A0A7P0P2U7_HUMAN,tr|A0A7I2YQU8|A0A7I2YQU8_HUMAN,tr|E5RJU8|E5RJU8_HUMAN,tr|A0A7I2V651|A0A7I2V651_HUMAN,tr|E5RIF8|E5RIF8_HUMAN,tr|A0A7I2YQN9|A0A7I2YQN9_HUMAN,tr|A0A7I2V2V1|A0A7I2V2V1_HUMAN" 11 1198.6418 0.96 28312 11997 2 1198.647227 600.3282 Ras GTPase-activating protein-binding protein 1 OS=Homo sapiens OX=9606 GN=G3BP1 PE=1 SV=1 9.75 2449.2 - 1.44E+06 - - - 4.4993 - 2.178 0.387 - 268.6 1 1 0 0.0054 11 0 0 0 3.94E+07 4.10E+07 - - - 4.0035 0.9555 221125_WJC_METTL3_EV_vs_WT_F03.11999.11999.2 2.5 12-Jun K.DALENLR.V "sp|O95999|BCL10_HUMAN,tr|A0A087WWW9|A0A087WWW9_HUMAN" 2 829.4294 3.07 28314 11999 2 829.429862 415.722 B-cell lymphoma\leukemia 10 OS=Homo sapiens OX=9606 GN=BCL10 PE=1 SV=1 4.37 2449.4 - 476833 - - - 0.5799 - 1.109 0.046 - 115.4 1 2 0 0.0005 7 0 0 0 6.75E+06 2.20E+06 - - - -0.2916 0.7758 221125_WJC_METTL3_EV_vs_WT_F03.12000.12000.2 12.6 12-May R.INIPPQR.G "sp|Q13283|G3BP1_HUMAN,tr|A0A7I2V5M7|A0A7I2V5M7_HUMAN,tr|A0A7P0P2U7|A0A7P0P2U7_HUMAN,tr|A0A7I2YQU8|A0A7I2YQU8_HUMAN,tr|A0A7I2V548|A0A7I2V548_HUMAN,tr|A0A7I2V565|A0A7I2V565_HUMAN,tr|A0A7I2YQN9|A0A7I2YQN9_HUMAN" 7 836.4868 1.67 28315 12000 2 836.488438 419.2507 Ras GTPase-activating protein-binding protein 1 OS=Homo sapiens OX=9606 GN=G3BP1 PE=1 SV=1 9.75 2449.6 - 453834 - - - 1.914 - 1.056 0 - 83.9 3 2 0 0.0016 7 0 0 0 1.44E+07 8.61E+06 - - - -1 0.9995 221125_WJC_METTL3_EV_vs_WT_F03.12001.12001.3 0.00298 13/36 R.SLHDALC[160.03]VVK[136.11].R "sp|P17987|TCPA_HUMAN,tr|F5GZ03|F5GZ03_HUMAN,tr|F5H282|F5H282_HUMAN,tr|E7EQR6|E7EQR6_HUMAN,tr|E7ERF2|E7ERF2_HUMAN" 5 1148.6103 0.77 28316 12001 3 1148.610221 383.8774 T-complex protein 1 subunit alpha OS=Homo sapiens OX=9606 GN=TCP1 PE=1 SV=1 6.46 2449.7 - 426247 - - - -0.094 - 1.953 0.303 - 156.2 1 2 0 -0.0001 10 0 0 0 6.72E+06 8.69E+06 - - - 3.873 0.9994 221125_WJC_METTL3_EV_vs_WT_F03.12004.12004.2 0.0176 16-Jul R.EPFTIAQGK.G "sp|P35659|DEK_HUMAN,tr|H0Y8X0|H0Y8X0_HUMAN,tr|H0Y993|H0Y993_HUMAN,tr|A0A494C028|A0A494C028_HUMAN,tr|D6R9L5|D6R9L5_HUMAN,tr|A0A494C198|A0A494C198_HUMAN,tr|D6RDA2|D6RDA2_HUMAN" 7 989.5182 0.83 28317 12004 2 989.519189 495.7664 Protein DEK OS=Homo sapiens OX=9606 GN=DEK PE=1 SV=1 6.1 2450.1 - 2.29E+06 - - - 1.0035 - 1.635 0.359 - 196 1 2 0 0.001 9 0 0 0 1.27E+08 1.53E+08 - - - 3.1146 0.9953 221125_WJC_METTL3_EV_vs_WT_F03.12005.12005.2 0.39 12-Jul K.TAWLDGK.H "sp|P23284|PPIB_HUMAN,tr|A0A7P0Z497|A0A7P0Z497_HUMAN,tr|A0A7P0TB45|A0A7P0TB45_HUMAN" 3 789.4021 0.38 28318 12005 2 789.402462 395.7083 Peptidyl-prolyl cis-trans isomerase B OS=Homo sapiens OX=9606 GN=PPIB PE=1 SV=2 5.5 2450.2 - 2.40E+06 - - - 0.4535 - 1.247 0.198 - 229.2 1 2 0 0.0004 7 0 0 0 7.37E+07 1.92E+08 - - - 1.2027 0.987 221125_WJC_METTL3_EV_vs_WT_F03.12006.12006.2 5.75E-06 20-Dec M.GLLSNNNQALR[166.11].R "sp|Q13283|G3BP1_HUMAN,tr|A0A7I2YQB1|A0A7I2YQB1_HUMAN,tr|A0A7I2V5M7|A0A7I2V5M7_HUMAN,tr|E5RH42|E5RH42_HUMAN,tr|A0A7P0P2U7|A0A7P0P2U7_HUMAN,tr|A0A7I2YQU8|A0A7I2YQU8_HUMAN,tr|E5RJU8|E5RJU8_HUMAN,tr|A0A7I2V651|A0A7I2V651_HUMAN,tr|E5RIF8|E5RIF8_HUMAN,tr|A0A7I2YQN9|A0A7I2YQN9_HUMAN,tr|A0A7I2V2V1|A0A7I2V2V1_HUMAN" 11 1208.6501 0.96 28319 12006 2 1208.650897 605.3323 Ras GTPase-activating protein-binding protein 1 OS=Homo sapiens OX=9606 GN=G3BP1 PE=1 SV=1 9.75 2450.2 - 1.90E+06 - - - 0.6561 - 2.582 0.343 - 468.5 1 1 0 0.0008 11 0 0 0 3.94E+07 4.10E+07 - - - 4.1402 0.9845 221125_WJC_METTL3_EV_vs_WT_F03.12008.12008.2 0.00141 16-Aug R.RVAVPVLVK.D "sp|Q9H2Z4|NKX24_HUMAN,sp|P43699|NKX21_HUMAN" 2 979.6542 1.66 28321 12008 2 979.654229 490.8344 Homeobox protein Nkx-2.4 OS=Homo sapiens OX=9606 GN=NKX2-4 PE=1 SV=3 11 2450.4 - 964966 - - - -0.0071 - 1.574 0.014 - 166.6 2 2 0 0 9 0 0 0 4.02E+07 2.41E+07 - - - 0.3223 0.9997 221125_WJC_METTL3_EV_vs_WT_F03.12014.12014.2 0.000512 16-Sep R.FLGTTC[160.03]YDR[166.11].S sp|O43172|PRP4_HUMAN 1 1141.5102 2.76 28325 12014 2 1141.510973 571.7624 U4\U6 small nuclear ribonucleoprotein Prp4 OS=Homo sapiens OX=9606 GN=PRPF4 PE=1 SV=2 5.83 2451.2 - 2.14E+06 - - - 0.7078 - 1.525 0.456 - 223.7 1 2 0 0.0008 9 0 0 0 1.36E+08 4.91E+07 - - - 3.6296 0.9975 221125_WJC_METTL3_EV_vs_WT_F03.12020.12020.2 0.0239 16-Sep K.TWVASNEIK[136.11].D "sp|O75175|CNOT3_HUMAN,tr|B7Z6J7|B7Z6J7_HUMAN,tr|A0A2R8Y7Z8|A0A2R8Y7Z8_HUMAN,tr|H7C148|H7C148_HUMAN" 4 1054.5539 0.97 28331 12020 2 1054.555244 528.2842 CCR4-NOT transcription complex subunit 3 OS=Homo sapiens OX=9606 GN=CNOT3 PE=1 SV=1 5.66 2451.6 - 1.00E+06 - - - 1.3124 - 1.575 0.217 - 314 1 2 0 0.0014 9 0 0 0 2.70E+07 2.78E+07 - - - 1.9575 0.9992 221125_WJC_METTL3_EV_vs_WT_F03.12021.12021.3 0.118 Nov-36 R.LYHPTVPLAR[166.11].E "sp|Q8IUF8|RIOX2_HUMAN,tr|H0Y9L8|H0Y9L8_HUMAN" 2 1175.669 0.86 28332 12021 3 1175.669 392.897 Ribosomal oxygenase 2 OS=Homo sapiens OX=9606 GN=RIOX2 PE=1 SV=1 8.75 2451.8 - 972067 - - - -0.0408 - 2.131 0.248 - 212.3 1 2 0 0 10 0 0 0 2.40E+07 2.79E+07 - - - 3.5145 0.9953 221125_WJC_METTL3_EV_vs_WT_F03.12022.12022.2 0.00538 16-Sep R.NNLVIDTPR.V "sp|Q9P2D1|CHD7_HUMAN,sp|Q9HCK8|CHD8_HUMAN,tr|A0A2R8Y840|A0A2R8Y840_HUMAN,tr|H0YJG4|H0YJG4_HUMAN" 4 1040.5615 1.96 28333 12022 2 1040.567032 521.288 Chromodomain-helicase-DNA-binding protein 7 OS=Homo sapiens OX=9606 GN=CHD7 PE=1 SV=3 5.84 2451.8 - 881823 - - - 5.3567 - 2.021 0.423 - 476.1 1 2 0 0.0056 9 0 0 0 4.25E+07 2.16E+07 - - - 4.1991 0.9997 221125_WJC_METTL3_EV_vs_WT_F03.12023.12023.2 0.00345 18-Oct K.MAQELYMEQK[136.11].N sp|P55884|EIF3B_HUMAN 1 1277.5875 0.45 28334 12023 2 1277.588843 639.801 Eukaryotic translation initiation factor 3 subunit B OS=Homo sapiens OX=9606 GN=EIF3B PE=1 SV=3 4.53 2451.9 - 756765 - - - 1.016 - 2.018 0.417 - 404.4 1 2 0 0.0013 10 0 0 0 1.07E+07 2.36E+07 - - - 4.0803 0.9999 221125_WJC_METTL3_EV_vs_WT_F03.12024.12024.2 5.39E-06 20-Dec R.LAQDAEVELER.Q "sp|P26572|MGAT1_HUMAN,tr|D6RB69|D6RB69_HUMAN,tr|D6RD15|D6RD15_HUMAN,tr|D6RBS3|D6RBS3_HUMAN,tr|D6RAK2|D6RAK2_HUMAN,tr|D6RHZ8|D6RHZ8_HUMAN,tr|D6R9U2|D6R9U2_HUMAN,tr|D6RA48|D6RA48_HUMAN,tr|D6RF69|D6RF69_HUMAN" 9 1271.6357 1.12 28335 12024 2 1271.637322 636.8251 "Alpha-1,3-mannosyl-glycoprotein 2-beta-N-acetylglucosaminyltransferase OS=Homo sapiens OX=9606 GN=MGAT1 PE=1 SV=2" 4 2452.1 - 738356 - - - 1.2401 - 2.678 0.49 - 605.4 1 2 0 0.0016 11 0 0 0 2.87E+07 2.57E+07 - - - 5.3245 0.9998 221125_WJC_METTL3_EV_vs_WT_F03.12025.12025.2 1.42E-05 20-Nov K.EAAFDDAVEER.V "sp|Q09028|RBBP4_HUMAN,tr|E9PIC4|E9PIC4_HUMAN,tr|E9PNS2|E9PNS2_HUMAN,tr|E9PNS6|E9PNS6_HUMAN" 4 1250.5415 2 28336 12025 2 1250.539912 626.278 Histone-binding protein RBBP4 OS=Homo sapiens OX=9606 GN=RBBP4 PE=1 SV=3 3.83 2452.2 - 683765 - - - -1.2786 - 1.986 0.525 - 482.8 1 2 0 -0.0016 11 0 0 0 3.02E+07 1.51E+07 - - - 4.7743 0.9996 221125_WJC_METTL3_EV_vs_WT_F03.12027.12027.2 0.00885 20-Sep R.IASPEGQDYLK.G sp|Q9Y3I0|RTCB_HUMAN 1 1219.6085 1.16 28337 12027 2 1219.609742 610.8115 RNA-splicing ligase RtcB homolog OS=Homo sapiens OX=9606 GN=RTCB PE=1 SV=1 4.37 2452.4 - 1.34E+07 - - - 1.0446 - 2.111 0.326 - 309.6 1 2 0 0.0013 11 0 0 0 3.27E+08 2.81E+08 - - - 3.4697 0.9968 221125_WJC_METTL3_EV_vs_WT_F03.12030.12030.2 3.81 18-Aug R.ALELDGQSVK[136.11].A "sp|Q9UNE7|CHIP_HUMAN,tr|H3BS86|H3BS86_HUMAN" 2 1066.575 0.91 28340 12030 2 1066.577097 534.2948 E3 ubiquitin-protein ligase CHIP OS=Homo sapiens OX=9606 GN=STUB1 PE=1 SV=2 4.37 2452.6 - 2.30E+06 - - - 1.9764 - 1.725 0.204 - 195.3 1 2 0 0.0021 10 0 0 0 5.33E+07 5.83E+07 - - - 2.069 0.9998 221125_WJC_METTL3_EV_vs_WT_F03.12031.12031.2 0.000103 18-Sep K.MAQELYMEQK.N sp|P55884|EIF3B_HUMAN 1 1269.5733 0.48 28341 12031 2 1269.572976 635.7939 Eukaryotic translation initiation factor 3 subunit B OS=Homo sapiens OX=9606 GN=EIF3B PE=1 SV=3 4.53 2452.6 - 1.26E+06 - - - -0.2906 - 1.883 0.482 - 343.9 1 2 0 -0.0004 10 0 0 0 1.05E+07 2.18E+07 - - - 4.3675 1 221125_WJC_METTL3_EV_vs_WT_F03.12032.12032.3 3.49E-05 18/44 M.VMEK[136.11]PSPLLVGR[166.11].E "sp|Q13283|G3BP1_HUMAN,sp|Q9UN86|G3BP2_HUMAN,tr|A0A7I2V3E2|A0A7I2V3E2_HUMAN,tr|A0A7I2V5M7|A0A7I2V5M7_HUMAN,tr|A0A7I2V2R0|A0A7I2V2R0_HUMAN,tr|E5RH00|E5RH00_HUMAN,tr|E5RH42|E5RH42_HUMAN,tr|A0A7I2V4Y8|A0A7I2V4Y8_HUMAN,tr|D6RAC7|D6RAC7_HUMAN,tr|D6RGJ4|D6RGJ4_HUMAN,tr|A0A7I2V3C4|A0A7I2V3C4_HUMAN,tr|A0A7P0P2U7|A0A7P0P2U7_HUMAN,tr|A0A7I2V2S5|A0A7I2V2S5_HUMAN,tr|D6RB17|D6RB17_HUMAN,tr|A0A7I2YQU8|A0A7I2YQU8_HUMAN,tr|E5RJU8|E5RJU8_HUMAN,tr|A0A7I2YQS2|A0A7I2YQS2_HUMAN,tr|A0A7I2YQD9|A0A7I2YQD9_HUMAN,tr|D6R9A4|D6R9A4_HUMAN,tr|A0A7I2V651|A0A7I2V651_HUMAN,tr|E5RIF8|E5RIF8_HUMAN,tr|E5RI46|E5RI46_HUMAN,tr|A0A7I2YQN9|A0A7I2YQN9_HUMAN,tr|D6RBR0|D6RBR0_HUMAN,tr|D6RBW8|D6RBW8_HUMAN" 25 1342.7762 1.13 28342 12032 3 1342.777437 448.5993 Ras GTPase-activating protein-binding protein 1 OS=Homo sapiens OX=9606 GN=G3BP1 PE=1 SV=1 8.72 2452.7 - 1.23E+06 - - - 0.9495 - 2.55 0.456 - 469.7 1 2 0 0.0013 12 0 0 0 6.64E+08 5.90E+08 - - - 6.2183 0.999 221125_WJC_METTL3_EV_vs_WT_F03.12033.12033.2 0.00635 16-Jun R.NVDFNYATK.D "sp|Q8WWM7|ATX2L_HUMAN,tr|H3BSQ5|H3BSQ5_HUMAN,tr|H3BSK9|H3BSK9_HUMAN,tr|H3BUE3|H3BUE3_HUMAN,tr|H3BUF6|H3BUF6_HUMAN" 5 1070.5033 1.49 28343 12033 2 1070.503075 536.2589 Ataxin-2-like protein OS=Homo sapiens OX=9606 GN=ATXN2L PE=1 SV=2 5.83 2452.8 - 1.20E+06 - - - -0.1868 - 1.327 0.343 - 94.1 1 2 0 -0.0002 9 0 0 0 1.13E+08 7.63E+07 - - - 2.3928 0.9771 221125_WJC_METTL3_EV_vs_WT_F03.12035.12035.3 0.505 Jun-36 R.LYHPTVPLAR.E "sp|Q8IUF8|RIOX2_HUMAN,tr|H0Y9L8|H0Y9L8_HUMAN" 2 1165.6608 0.86 28345 12035 3 1165.661517 389.5609 Ribosomal oxygenase 2 OS=Homo sapiens OX=9606 GN=RIOX2 PE=1 SV=1 8.75 2452.9 - 876810 - - - 0.634 - 1.544 0.178 - 54.9 11 2 0 0.0007 10 0 0 0 2.40E+07 2.80E+07 - - - 1.3109 0.9998 221125_WJC_METTL3_EV_vs_WT_F03.12036.12036.2 1.46E-05 16-Nov R.NVDFNYATK[136.11].D "sp|Q8WWM7|ATX2L_HUMAN,tr|H3BSQ5|H3BSQ5_HUMAN,tr|H3BSK9|H3BSK9_HUMAN,tr|H3BUE3|H3BUE3_HUMAN,tr|H3BUF6|H3BUF6_HUMAN" 5 1078.5175 1.5 28346 12036 2 1078.518862 540.266 Ataxin-2-like protein OS=Homo sapiens OX=9606 GN=ATXN2L PE=1 SV=2 5.83 2453.1 - 830466 - - - 1.286 - 2.002 0.464 - 331.4 1 2 0 0.0014 9 0 0 0 1.14E+08 7.63E+07 - - - 4.4759 0.9985 221125_WJC_METTL3_EV_vs_WT_F03.12039.12039.2 0.0205 20-Sep K.VVSPWNSEDAK[136.11].G "sp|P11177|ODPB_HUMAN,tr|F8WF02|F8WF02_HUMAN,tr|C9J634|C9J634_HUMAN" 3 1238.6023 1.32 28349 12039 2 1238.605273 620.3084 "Pyruvate dehydrogenase E1 component subunit beta, mitochondrial OS=Homo sapiens OX=9606 GN=PDHB PE=1 SV=3" 4.37 2453.3 - 291073 - - - 2.4269 - 1.702 0.349 - 251.6 1 2 0 0.003 11 0 0 0 3.70E+07 2.80E+07 - - - 3.0564 0.9992 221125_WJC_METTL3_EV_vs_WT_F03.12042.12042.2 0.05 16-Aug R.FLGTTC[160.03]YDR.S sp|O43172|PRP4_HUMAN 1 1131.5019 2.76 28350 12042 2 1131.502479 566.7582 U4\U6 small nuclear ribonucleoprotein Prp4 OS=Homo sapiens OX=9606 GN=PRPF4 PE=1 SV=2 5.83 2453.7 - 7.33E+06 - - - 0.5161 - 1.293 0.389 - 169.3 1 2 0 0.0006 9 0 0 0 1.36E+08 4.91E+07 - - - 2.6574 1 221125_WJC_METTL3_EV_vs_WT_F03.12043.12043.3 3.56E-07 Dec-44 M.VMEKPSPLLVGR.E "sp|Q13283|G3BP1_HUMAN,sp|Q9UN86|G3BP2_HUMAN,tr|A0A7I2V3E2|A0A7I2V3E2_HUMAN,tr|A0A7I2V5M7|A0A7I2V5M7_HUMAN,tr|A0A7I2V2R0|A0A7I2V2R0_HUMAN,tr|E5RH00|E5RH00_HUMAN,tr|E5RH42|E5RH42_HUMAN,tr|A0A7I2V4Y8|A0A7I2V4Y8_HUMAN,tr|D6RAC7|D6RAC7_HUMAN,tr|D6RGJ4|D6RGJ4_HUMAN,tr|A0A7I2V3C4|A0A7I2V3C4_HUMAN,tr|A0A7P0P2U7|A0A7P0P2U7_HUMAN,tr|A0A7I2V2S5|A0A7I2V2S5_HUMAN,tr|D6RB17|D6RB17_HUMAN,tr|A0A7I2YQU8|A0A7I2YQU8_HUMAN,tr|E5RJU8|E5RJU8_HUMAN,tr|A0A7I2YQS2|A0A7I2YQS2_HUMAN,tr|A0A7I2YQD9|A0A7I2YQD9_HUMAN,tr|D6R9A4|D6R9A4_HUMAN,tr|A0A7I2V651|A0A7I2V651_HUMAN,tr|E5RIF8|E5RIF8_HUMAN,tr|E5RI46|E5RI46_HUMAN,tr|A0A7I2YQN9|A0A7I2YQN9_HUMAN,tr|D6RBR0|D6RBR0_HUMAN,tr|D6RBW8|D6RBW8_HUMAN" 25 1324.7537 1.13 28351 12043 3 1324.753707 442.5918 Ras GTPase-activating protein-binding protein 1 OS=Homo sapiens OX=9606 GN=G3BP1 PE=1 SV=1 8.72 2453.7 - 2.76E+06 - - - 0.0113 - 2.484 0.498 - 190.7 1 2 0 0 12 0 0 0 6.64E+08 5.90E+08 - - - 6.6142 0.9997 221125_WJC_METTL3_EV_vs_WT_F03.12044.12044.2 0.00102 20-Oct R.LVASAYSIAQK.A "sp|O95861|BPNT1_HUMAN,tr|F8W1J0|F8W1J0_HUMAN,tr|F8VVW8|F8VVW8_HUMAN,tr|A6NF51|A6NF51_HUMAN,tr|F8VZG4|F8VZG4_HUMAN" 5 1149.6394 1.29 28352 12044 2 1149.640027 575.827 "3'(2'),5'-bisphosphate nucleotidase 1 OS=Homo sapiens OX=9606 GN=BPNT1 PE=1 SV=1" 8.59 2453.8 - 1.18E+06 - - - 0.568 - 2.089 0.365 - 259.3 1 2 0 0.0007 11 0 0 0 1.60E+07 1.24E+07 - - - 3.7296 0.982 221125_WJC_METTL3_EV_vs_WT_F03.12045.12045.2 0.00133 20-Sep F.VVFDDSEPVQR.L "sp|Q9UN86|G3BP2_HUMAN,tr|A0A7I2V647|A0A7I2V647_HUMAN,tr|A0A7I2YQD9|A0A7I2YQD9_HUMAN,tr|A0A7I2V382|A0A7I2V382_HUMAN,tr|A0A7I2V3P9|A0A7I2V3P9_HUMAN" 5 1289.6252 0.12 28353 12045 2 1289.623955 645.8199 Ras GTPase-activating protein-binding protein 2 OS=Homo sapiens OX=9606 GN=G3BP2 PE=1 SV=2 4.03 2454 - 1.01E+06 - - - -0.9507 - 1.731 0.436 - 265.7 1 1 0 -0.0012 11 0 0 0 2.90E+07 2.51E+08 - - - 3.7453 0.9955 221125_WJC_METTL3_EV_vs_WT_F03.12046.12046.2 0.0342 20-Oct K.SILVSPTGPSR[166.11].V sp|Q14684|RRP1B_HUMAN 1 1122.6272 0.83 28354 12046 2 1122.622562 562.3209 Ribosomal RNA processing protein 1 homolog B OS=Homo sapiens OX=9606 GN=RRP1B PE=1 SV=3 9.47 2454 - 872944 - - - -4.1697 - 2.1 0.289 - 280.8 1 2 0 -0.0047 11 0 0 0 4.00E+07 4.81E+07 - - - 3.1812 0.9999 221125_WJC_METTL3_EV_vs_WT_F03.12051.12051.2 3.18E-05 16-Aug R.DPYGFGDSR.D sp|Q9HCD5|NCOA5_HUMAN 1 1012.425 1.83 28357 12051 2 1012.425234 507.2198 Nuclear receptor coactivator 5 OS=Homo sapiens OX=9606 GN=NCOA5 PE=1 SV=2 4.21 2454.6 - 5.01E+06 - - - 0.2074 - 1.701 0.624 - 254.1 1 2 0 0.0002 9 0 0 0 8.33E+07 4.55E+07 - - - 5.1866 0.9983 221125_WJC_METTL3_EV_vs_WT_F03.12052.12052.2 0.0193 14-Jul K.MLVIEQC[160.03]K.N "sp|P48643|TCPE_HUMAN,tr|E9PCA1|E9PCA1_HUMAN,tr|B7ZAR1|B7ZAR1_HUMAN,tr|E7ENZ3|E7ENZ3_HUMAN" 4 1019.5144 0.58 28358 12052 2 1019.514694 510.7645 T-complex protein 1 subunit epsilon OS=Homo sapiens OX=9606 GN=CCT5 PE=1 SV=1 5.75 2454.6 - 4.47E+06 - - - 0.3139 - 1.613 0.202 - 199.1 1 2 0 0.0003 8 0 0 0 1.16E+08 1.99E+08 - - - 1.9748 0.9997 221125_WJC_METTL3_EV_vs_WT_F03.12053.12053.2 0.00461 16-Sep K.VELQELNDR.F "sp|P08670|VIME_HUMAN,sp|P17661|DESM_HUMAN,tr|B0YJC4|B0YJC4_HUMAN,tr|A0A1B0GTT5|A0A1B0GTT5_HUMAN" 4 1114.5619 1.94 28359 12053 2 1114.561623 558.2882 Vimentin OS=Homo sapiens OX=9606 GN=VIM PE=1 SV=4 4.14 2454.7 - 3.24E+06 - - - -0.2055 - 1.946 0.365 - 433.6 1 2 0 -0.0002 9 0 0 0 5.70E+09 2.94E+09 - - - 3.6629 0.9997 221125_WJC_METTL3_EV_vs_WT_F03.12054.12054.2 0.0198 16-Oct K.VELQELNDR[166.11].F "sp|P08670|VIME_HUMAN,sp|P17661|DESM_HUMAN,tr|B0YJC4|B0YJC4_HUMAN,tr|A0A1B0GTT5|A0A1B0GTT5_HUMAN" 4 1124.5701 1.94 28360 12054 2 1124.570239 563.2923 Vimentin OS=Homo sapiens OX=9606 GN=VIM PE=1 SV=4 4.14 2454.7 - 2.38E+06 - - - 0.104 - 2.176 0.329 - 543.8 1 2 0 0.0001 9 0 0 0 5.70E+09 2.94E+09 - - - 3.7203 0.9951 221125_WJC_METTL3_EV_vs_WT_F03.12056.12056.2 0.355 18-Jul R.GMGSLDAMDK[136.11].H "sp|P12268|IMDH2_HUMAN,tr|A0A7I2YQK5|A0A7I2YQK5_HUMAN,tr|H0Y4R1|H0Y4R1_HUMAN,tr|A0A7I2V2T3|A0A7I2V2T3_HUMAN,tr|E7ETK5|E7ETK5_HUMAN" 5 1031.4507 1.07 28362 12056 2 1031.450053 516.7326 Inosine-5'-monophosphate dehydrogenase 2 OS=Homo sapiens OX=9606 GN=IMPDH2 PE=1 SV=2 4.21 2454.9 - 1.91E+06 - - - -0.6438 - 1.063 0.264 - 108.9 1 2 0 -0.0007 10 0 0 0 5.35E+07 4.98E+07 - - - 1.1612 0.9997 221125_WJC_METTL3_EV_vs_WT_F03.12063.12063.2 0.000476 14-Sep K.IPAMTIAK[136.11].N "sp|P10809|CH60_HUMAN,tr|A0A7I2V2X6|A0A7I2V2X6_HUMAN,tr|A0A7I2YQK6|A0A7I2YQK6_HUMAN,tr|A0A7I2V599|A0A7I2V599_HUMAN" 4 851.503 2.28 28367 12063 2 851.50295 426.7588 "60 kDa heat shock protein, mitochondrial OS=Homo sapiens OX=9606 GN=HSPD1 PE=1 SV=2" 8.75 2455.8 - 2.51E+06 - - - -0.0705 - 1.772 0.359 - 229.5 1 2 0 -0.0001 8 0 0 0 5.80E+08 2.54E+08 - - - 3.418 0.9993 221125_WJC_METTL3_EV_vs_WT_F03.12064.12064.2 6.82E-06 22-Nov R.INVYYNEATGGK[136.11].Y sp|P68371|TBB4B_HUMAN 1 1335.655 0.88 28368 12064 2 1335.659583 668.8348 Tubulin beta-4B chain OS=Homo sapiens OX=9606 GN=TUBB4B PE=1 SV=1 6 2455.9 - 480384 - - - 3.4081 - 2.238 0.534 - 371 1 2 0 0.0046 12 0 0 0 2.53E+08 2.86E+08 - - - 5.1033 0.9975 221125_WJC_METTL3_EV_vs_WT_F03.12065.12065.2 0.000168 22-Sep M.VMEK[136.11]PSPLLVGR[166.11].E "sp|Q13283|G3BP1_HUMAN,sp|Q9UN86|G3BP2_HUMAN,tr|A0A7I2V3E2|A0A7I2V3E2_HUMAN,tr|A0A7I2V5M7|A0A7I2V5M7_HUMAN,tr|A0A7I2V2R0|A0A7I2V2R0_HUMAN,tr|E5RH00|E5RH00_HUMAN,tr|E5RH42|E5RH42_HUMAN,tr|A0A7I2V4Y8|A0A7I2V4Y8_HUMAN,tr|D6RAC7|D6RAC7_HUMAN,tr|D6RGJ4|D6RGJ4_HUMAN,tr|A0A7I2V3C4|A0A7I2V3C4_HUMAN,tr|A0A7P0P2U7|A0A7P0P2U7_HUMAN,tr|A0A7I2V2S5|A0A7I2V2S5_HUMAN,tr|D6RB17|D6RB17_HUMAN,tr|A0A7I2YQU8|A0A7I2YQU8_HUMAN,tr|E5RJU8|E5RJU8_HUMAN,tr|A0A7I2YQS2|A0A7I2YQS2_HUMAN,tr|A0A7I2YQD9|A0A7I2YQD9_HUMAN,tr|D6R9A4|D6R9A4_HUMAN,tr|A0A7I2V651|A0A7I2V651_HUMAN,tr|E5RIF8|E5RIF8_HUMAN,tr|E5RI46|E5RI46_HUMAN,tr|A0A7I2YQN9|A0A7I2YQN9_HUMAN,tr|D6RBR0|D6RBR0_HUMAN,tr|D6RBW8|D6RBW8_HUMAN" 25 1342.7762 1.08 28369 12065 2 1342.781023 672.3954 Ras GTPase-activating protein-binding protein 1 OS=Homo sapiens OX=9606 GN=G3BP1 PE=1 SV=1 8.72 2456 - 812252 - - - 3.6201 - 1.627 0.421 - 148 1 2 0 0.0049 12 0 0 0 5.20E+07 4.80E+07 - - - 3.4297 0.9999 221125_WJC_METTL3_EV_vs_WT_F03.12067.12067.2 3.92E-06 26-Sep K.TALPAQSAATLPAR[166.11].T "sp|Q01082|SPTB2_HUMAN,tr|A0A087WUZ3|A0A087WUZ3_HUMAN" 2 1376.7651 1.64 28371 12067 2 1376.765627 689.3898 "Spectrin beta chain, non-erythrocytic 1 OS=Homo sapiens OX=9606 GN=SPTBN1 PE=1 SV=2" 9.41 2456.3 - 263384 - - - 0.3581 - 2.11 0.549 - 244.5 1 2 0 0.0005 14 0 0 0 9.23E+06 5.62E+06 - - - 4.9695 0.9992 221125_WJC_METTL3_EV_vs_WT_F03.12070.12070.2 0.033 12-Jul K.SASSFFK.E "sp|Q8NDD1|CA131_HUMAN,tr|Q5TBI2|Q5TBI2_HUMAN,tr|Q5TBH9|Q5TBH9_HUMAN" 3 772.3756 0.89 28372 12070 2 772.375456 387.1951 Uncharacterized protein C1orf131 OS=Homo sapiens OX=9606 GN=C1orf131 PE=1 SV=4 8.47 2456.7 - 686933 - - - -0.1282 - 1.515 0.296 - 170.4 1 2 0 -0.0001 7 0 0 0 1.31E+07 1.48E+07 - - - 2.5435 0.9998 221125_WJC_METTL3_EV_vs_WT_F03.12073.12073.2 1.69E-07 26-Nov K.TALPAQSAATLPAR.T "sp|Q01082|SPTB2_HUMAN,tr|A0A087WUZ3|A0A087WUZ3_HUMAN" 2 1366.7569 1.64 28375 12073 2 1366.75966 684.3857 "Spectrin beta chain, non-erythrocytic 1 OS=Homo sapiens OX=9606 GN=SPTBN1 PE=1 SV=2" 9.41 2457.1 - 421009 - - - 2.0457 - 2.242 0.572 - 390.3 1 2 0 0.0028 14 0 0 0 9.23E+06 5.62E+06 - - - 5.291 0.9999 221125_WJC_METTL3_EV_vs_WT_F03.12079.12079.2 0.000176 18-Oct K.YLEC[160.03]SALTQR[166.11].G "sp|P63000|RAC1_HUMAN,sp|P60763|RAC3_HUMAN,sp|P15153|RAC2_HUMAN,tr|B1AH77|B1AH77_HUMAN,tr|B1AH78|B1AH78_HUMAN,tr|J3KSC4|J3KSC4_HUMAN,tr|J3QLK0|J3QLK0_HUMAN,tr|B1AH80|B1AH80_HUMAN" 8 1249.6 1.07 28379 12079 2 1249.600602 625.8073 Ras-related C3 botulinum toxin substrate 1 OS=Homo sapiens OX=9606 GN=RAC1 PE=1 SV=1 5.99 2457.8 - 4.96E+06 - - - 0.4481 - 1.895 0.52 - 355.3 1 2 0 0.0006 10 0 0 0 9.56E+07 8.94E+07 - - - 4.6658 0.9995 221125_WJC_METTL3_EV_vs_WT_F03.12081.12081.3 0.00717 Nov-36 K.IEAVEMHLTR[166.11].E sp|Q9UKN8|TF3C4_HUMAN 1 1207.6259 0.99 28381 12081 3 1207.625851 403.5492 General transcription factor 3C polypeptide 4 OS=Homo sapiens OX=9606 GN=GTF3C4 PE=1 SV=2 5.4 2458 - 490706 - - - -0.0099 - 1.749 0.325 - 122.1 1 2 0 0 10 0 0 0 1.47E+07 1.48E+07 - - - 3.7961 0.9972 221125_WJC_METTL3_EV_vs_WT_F03.12084.12084.2 0.127 16-Jul R.AMIENFNAK[136.11].Y "sp|Q9BSU3|NAA11_HUMAN,sp|P41227|NAA10_HUMAN,tr|A8MWP7|A8MWP7_HUMAN,tr|F8W808|F8W808_HUMAN,tr|C9JW55|C9JW55_HUMAN,tr|C9JN83|C9JN83_HUMAN" 6 1044.5154 0.6 28382 12084 2 1044.513507 523.265 N-alpha-acetyltransferase 11 OS=Homo sapiens OX=9606 GN=NAA11 PE=1 SV=3 6.05 2458.4 - 2.30E+06 - - - -1.7798 - 1.296 0.301 - 145.5 1 2 0 -0.0019 9 0 0 0 2.88E+07 4.84E+07 - - - 2.0137 0.9985 221125_WJC_METTL3_EV_vs_WT_F03.12086.12086.2 0.000356 22-Oct R.INVYYNEATGGK.Y sp|P68371|TBB4B_HUMAN 1 1327.6408 0.88 28384 12086 2 1327.637041 664.8277 Tubulin beta-4B chain OS=Homo sapiens OX=9606 GN=TUBB4B PE=1 SV=1 6 2458.6 - 3.76E+06 - - - -2.8547 - 1.522 0.435 - 165.8 1 2 0 -0.0038 12 0 0 0 2.53E+08 2.86E+08 - - - 3.3579 0.9994 221125_WJC_METTL3_EV_vs_WT_F03.12089.12089.2 0.0102 16-Aug R.SLYGLGGSK.R "sp|P48668|K2C6C_HUMAN,sp|P04259|K2C6B_HUMAN,sp|P02538|K2C6A_HUMAN" 3 880.4654 84.55 28385 12089 2 880.464926 441.24 "Keratin, type II cytoskeletal 6C OS=Homo sapiens OX=9606 GN=KRT6C PE=1 SV=3" 8.31 2459 - 8.30E+07 - - - -0.5747 - 1.599 0.332 - 175.4 1 2 0 -0.0005 9 0 0 0 7.90E+09 9.34E+07 - - - 2.8509 0.9996 221125_WJC_METTL3_EV_vs_WT_F03.12090.12090.2 0.00318 14-Aug K.FELDTSER.K sp|P04844|RPN2_HUMAN 1 995.456 1 28386 12090 2 995.45553 498.7353 Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit 2 OS=Homo sapiens OX=9606 GN=RPN2 PE=1 SV=3 4.14 2459.1 - 3.14E+06 - - - -0.4621 - 1.627 0.391 - 220.3 1 2 0 -0.0005 8 0 0 0 9.39E+07 9.35E+07 - - - 3.3968 1 221125_WJC_METTL3_EV_vs_WT_F03.12093.12093.2 7.04E-08 18-Nov R.SAYNVYVAER.F "sp|Q00059|TFAM_HUMAN,tr|H7BYN3|H7BYN3_HUMAN" 2 1170.5669 3.86 28389 12093 2 1170.565822 586.2907 "Transcription factor A, mitochondrial OS=Homo sapiens OX=9606 GN=TFAM PE=1 SV=1" 5.72 2459.3 - 1.10E+06 - - - -0.9525 - 2.095 0.625 - 362.6 1 2 0 -0.0011 10 0 0 0 4.52E+08 1.17E+08 - - - 5.7212 0.8358 221125_WJC_METTL3_EV_vs_WT_F03.12094.12094.2 0.471 12-Sep A.ILDLIK[136.11]K[136.11].H "sp|Q14765|STAT4_HUMAN,sp|Q86XI2|CNDG2_HUMAN,sp|P26196|DDX6_HUMAN,tr|H0Y6U5|H0Y6U5_HUMAN" 4 857.5921 1.07 28390 12094 2 857.591614 429.8033 Signal transducer and activator of transcription 4 OS=Homo sapiens OX=9606 GN=STAT4 PE=1 SV=1 8.59 2459.4 - 976668 - - - -0.555 - 1.551 0.137 - 196.1 1 1 0 -0.0005 7 0 0 0 1.90E+07 1.78E+07 - - - 1.4434 0.9996 221125_WJC_METTL3_EV_vs_WT_F03.12096.12096.3 0.00107 Nov-40 K.VGVHLLEPATR.D sp|Q9ULL5|PRR12_HUMAN 1 1190.6772 1.51 28392 12096 3 1190.67955 397.8997 Proline-rich protein 12 OS=Homo sapiens OX=9606 GN=PRR12 PE=1 SV=3 6.72 2459.7 - 555077 - - - 2.0098 - 1.961 0.37 - 120.2 1 2 0 0.0024 11 0 0 0 2.73E+07 1.81E+07 - - - 4.5776 0.9997 221125_WJC_METTL3_EV_vs_WT_F03.12102.12102.2 0.0102 20-Nov K.MQAGEEVTELR.R "sp|Q5T8P6|RBM26_HUMAN,tr|E2PSN0|E2PSN0_HUMAN,tr|A0A087X0H9|A0A087X0H9_HUMAN" 3 1261.5973 6.31 28396 12102 2 1261.59666 631.8059 RNA-binding protein 26 OS=Homo sapiens OX=9606 GN=RBM26 PE=1 SV=3 4.25 2460.4 - 1.00E+06 - - - -0.4685 - 1.867 0.366 - 429.1 1 2 0 -0.0006 11 0 0 0 2.77E+07 4.40E+06 - - - 3.4331 0.9998 221125_WJC_METTL3_EV_vs_WT_F03.12103.12103.2 7.60E-05 13/24 R.VAAALDDGSALGR.F "sp|P19971|TYPH_HUMAN,tr|A0A494C0L6|A0A494C0L6_HUMAN,tr|C9JGI3|C9JGI3_HUMAN" 3 1214.6255 999 28397 12103 2 1214.624327 608.32 Thymidine phosphorylase OS=Homo sapiens OX=9606 GN=TYMP PE=1 SV=2 4.21 2460.6 - 999440 - - - -0.9781 - 2.482 0.373 - 517.6 1 2 0 -0.0012 13 0 0 0 1.34E+07 0.00E+00 - - - 4.1287 0.9997 221125_WJC_METTL3_EV_vs_WT_F03.12107.12107.2 0.00121 16-Sep K.DGLTDVYNK[136.11].L "sp|P24752|THIL_HUMAN,tr|A0A5F9ZHJ7|A0A5F9ZHJ7_HUMAN,tr|A0A5F9ZHD4|A0A5F9ZHD4_HUMAN,tr|A0A5F9ZHH9|A0A5F9ZHH9_HUMAN,tr|A0A5F9ZHJ0|A0A5F9ZHJ0_HUMAN,tr|A0A5F9ZHL1|A0A5F9ZHL1_HUMAN,tr|A0A5F9ZI66|A0A5F9ZI66_HUMAN,tr|H0YEL7|H0YEL7_HUMAN" 8 1031.5015 1.25 28399 12107 2 1031.500896 516.758 "Acetyl-CoA acetyltransferase, mitochondrial OS=Homo sapiens OX=9606 GN=ACAT1 PE=1 SV=1" 4.21 2461.1 - 4.47E+06 - - - -0.5759 - 1.759 0.424 - 222.9 1 2 0 -0.0006 9 0 0 0 4.49E+08 3.59E+08 - - - 3.8063 0.9998 221125_WJC_METTL3_EV_vs_WT_F03.12108.12108.2 0.000352 16-Sep K.DGLTDVYNK.L "sp|P24752|THIL_HUMAN,tr|A0A5F9ZHJ7|A0A5F9ZHJ7_HUMAN,tr|A0A5F9ZHD4|A0A5F9ZHD4_HUMAN,tr|A0A5F9ZHH9|A0A5F9ZHH9_HUMAN,tr|A0A5F9ZHJ0|A0A5F9ZHJ0_HUMAN,tr|A0A5F9ZHL1|A0A5F9ZHL1_HUMAN,tr|A0A5F9ZI66|A0A5F9ZI66_HUMAN,tr|H0YEL7|H0YEL7_HUMAN" 8 1023.4873 1.25 28400 12108 2 1023.487038 512.7509 "Acetyl-CoA acetyltransferase, mitochondrial OS=Homo sapiens OX=9606 GN=ACAT1 PE=1 SV=1" 4.21 2461.1 - 4.07E+06 - - - -0.2462 - 1.882 0.423 - 210.4 1 2 0 -0.0003 9 0 0 0 4.49E+08 3.59E+08 - - - 3.9946 0.9996 221125_WJC_METTL3_EV_vs_WT_F03.12109.12109.2 0.00301 14-Sep R.ESFVDQVR[166.11].E "sp|Q9H4A3|WNK1_HUMAN,tr|F5GWT4|F5GWT4_HUMAN,tr|A0A6Q8PFM0|A0A6Q8PFM0_HUMAN,tr|H0YH68|H0YH68_HUMAN" 4 988.4853 1.73 28401 12109 2 988.485247 495.2499 Serine\threonine-protein kinase WNK1 OS=Homo sapiens OX=9606 GN=WNK1 PE=1 SV=2 4.37 2461.2 - 1.62E+06 - - - -0.084 - 1.571 0.374 - 270.8 1 2 0 -0.0001 8 0 0 0 9.31E+07 5.38E+07 - - - 3.1657 0.9979 221125_WJC_METTL3_EV_vs_WT_F03.12110.12110.2 0.682 14-Aug R.GLNISAVR.L "sp|P23588|IF4B_HUMAN,tr|E7EX17|E7EX17_HUMAN,tr|F8VSC7|F8VSC7_HUMAN,tr|F8VYE9|F8VYE9_HUMAN,tr|F8VRU1|F8VRU1_HUMAN,tr|F8VX11|F8VX11_HUMAN,tr|F8W0K0|F8W0K0_HUMAN,tr|F8VP89|F8VP89_HUMAN" 8 828.4818 2.29 28402 12110 2 828.480298 415.2482 Eukaryotic translation initiation factor 4B OS=Homo sapiens OX=9606 GN=EIF4B PE=1 SV=2 9.75 2461.4 - 1.04E+06 - - - -1.7538 - 1.649 0.23 - 284.6 1 2 0 -0.0015 8 0 0 0 1.16E+08 5.06E+07 - - - 2.2478 0.9919 221125_WJC_METTL3_EV_vs_WT_F03.12111.12111.2 0.000238 18-Sep K.EYITPAQISK.E sp|O94874|UFL1_HUMAN 1 1148.6077 0.95 28403 12111 2 1148.602605 575.3111 E3 UFM1-protein ligase 1 OS=Homo sapiens OX=9606 GN=UFL1 PE=1 SV=2 6.1 2461.5 - 906710 - - - -4.4706 - 1.754 0.298 - 241.5 1 2 0 -0.0051 10 0 0 0 1.69E+07 1.78E+07 - - - 2.8088 0.9728 221125_WJC_METTL3_EV_vs_WT_F03.12116.12116.2 7.13E-05 16-Oct R.PGGDTIFGK.L "sp|P49773|HINT1_HUMAN,tr|H0YC49|H0YC49_HUMAN,tr|A0A6Q8PGQ8|A0A6Q8PGQ8_HUMAN,tr|D6RE99|D6RE99_HUMAN,tr|D6REP8|D6REP8_HUMAN,tr|D6RC06|D6RC06_HUMAN,tr|D6RD60|D6RD60_HUMAN" 7 890.4498 1.78 28406 12116 2 890.447363 446.2322 Adenosine 5'-monophosphoramidase HINT1 OS=Homo sapiens OX=9606 GN=HINT1 PE=1 SV=2 6.26 2462.1 - 6.36E+06 - - - -2.7166 - 2.135 0.477 - 263.8 1 1 0 -0.0024 9 0 0 0 2.11E+08 1.19E+08 - - - 4.7576 0.8776 221125_WJC_METTL3_EV_vs_WT_F03.12117.12117.2 0.24 16-Jul K.TTLTAAITK.L "sp|P49411|EFTU_HUMAN,tr|H3BNU3|H3BNU3_HUMAN" 2 918.5386 6.3 28407 12117 2 918.536774 460.2766 "Elongation factor Tu, mitochondrial OS=Homo sapiens OX=9606 GN=TUFM PE=1 SV=2" 8.41 2462.2 - 1.82E+06 - - - -1.9847 - 1.252 0.007 - 94.4 5 2 0 -0.0018 9 0 0 0 2.12E+08 3.36E+07 - - - -0.5699 0.8415 221125_WJC_METTL3_EV_vs_WT_F03.12120.12120.2 3.33 16-Jun K.GQPFDVGPR.Y "sp|P27361|MK03_HUMAN,tr|E9PQW4|E9PQW4_HUMAN,tr|E9PJF0|E9PJF0_HUMAN,tr|E9PBK7|E9PBK7_HUMAN" 4 971.4825 1.87 28410 12120 2 971.479911 486.7485 Mitogen-activated protein kinase 3 OS=Homo sapiens OX=9606 GN=MAPK3 PE=1 SV=4 5.84 2462.6 - 416372 - - - -2.6434 - 1.065 0.094 - 69.3 7 2 0 -0.0026 9 0 0 0 2.23E+07 1.20E+07 - - - -0.4608 0.9921 221125_WJC_METTL3_EV_vs_WT_F03.12123.12123.2 0.842 12-Jun K.GYIDLSK[136.11].R "sp|P05198|IF2A_HUMAN,tr|H0YJS4|H0YJS4_HUMAN,tr|G3V4T5|G3V4T5_HUMAN" 3 802.4316 0.93 28411 12123 2 802.430386 402.2231 Eukaryotic translation initiation factor 2 subunit 1 OS=Homo sapiens OX=9606 GN=EIF2S1 PE=1 SV=3 5.83 2463 - 2.83E+06 - - - -1.5378 - 1.183 0.207 - 159.7 1 2 0 -0.0012 7 0 0 0 6.83E+07 7.37E+07 - - - 1.102 0.9998 221125_WJC_METTL3_EV_vs_WT_F03.12124.12124.2 5.13E-05 22-Dec K.VGDPQELNGITR.A "sp|P49327|FAS_HUMAN,tr|A0A0U1RQF0|A0A0U1RQF0_HUMAN" 2 1297.6626 0.87 28412 12124 2 1297.660477 649.8386 Fatty acid synthase OS=Homo sapiens OX=9606 GN=FASN PE=1 SV=3 4.37 2463.1 - 2.05E+06 - - - -1.6584 - 2.506 0.538 - 443.2 1 2 0 -0.0022 12 0 0 0 6.07E+07 7.00E+07 - - - 5.4312 0.9988 221125_WJC_METTL3_EV_vs_WT_F03.12125.12125.2 0.00762 16-Sep K.LSDGVAVLK.V "sp|P10809|CH60_HUMAN,tr|A0A7I2V2X6|A0A7I2V2X6_HUMAN,tr|A0A7I2YQK6|A0A7I2YQK6_HUMAN,tr|A0A7I2V599|A0A7I2V599_HUMAN" 4 900.528 1.24 28413 12125 2 900.525914 451.2713 "60 kDa heat shock protein, mitochondrial OS=Homo sapiens OX=9606 GN=HSPD1 PE=1 SV=2" 5.84 2463.2 - 2.22E+06 - - - -2.3531 - 1.65 0.358 - 125.6 1 2 0 -0.0021 9 0 0 0 9.35E+08 7.53E+08 - - - 3.1333 0.9914 221125_WJC_METTL3_EV_vs_WT_F03.12131.12131.2 0.181 12-Jun K.TEWLDGK[136.11].H "sp|Q9Y536|PAL4A_HUMAN,sp|A0A075B759|PAL4E_HUMAN,sp|P0DN37|PAL4G_HUMAN,sp|P0DN26|PAL4F_HUMAN,sp|A0A0B4J2A2|PAL4C_HUMAN,sp|F5H284|PAL4D_HUMAN,sp|A0A075B767|PAL4H_HUMAN,sp|P62937|PPIA_HUMAN,tr|A0A0H2UH34|A0A0H2UH34_HUMAN" 9 855.4218 1.04 28417 12131 2 855.421363 428.7182 Peptidyl-prolyl cis-trans isomerase A-like 4A OS=Homo sapiens OX=9606 GN=PPIAL4A PE=2 SV=1 4.37 2463.9 - 2.86E+06 - - - -0.491 - 1.138 0.174 - 170.2 1 2 0 -0.0004 7 0 0 0 2.74E+08 2.63E+08 - - - 0.7356 0.9993 221125_WJC_METTL3_EV_vs_WT_F03.12132.12132.2 0.115 14-Jul K.FELDTSER[166.11].K sp|P04844|RPN2_HUMAN 1 1005.4643 0.99 28418 12132 2 1005.462193 503.7394 Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit 2 OS=Homo sapiens OX=9606 GN=RPN2 PE=1 SV=3 4.14 2463.9 - 3.45E+06 - - - -2.0558 - 1.563 0.424 - 181.9 1 2 0 -0.0021 8 0 0 0 9.40E+07 9.52E+07 - - - 3.519 0.9996 221125_WJC_METTL3_EV_vs_WT_F03.12133.12133.2 1.74E-05 14-Sep R.NGDFLPTR[166.11].L "sp|P55036|PSMD4_HUMAN,sp|A2A3N6|PIPSL_HUMAN,tr|A6PVX3|A6PVX3_HUMAN,tr|Q5VWC4|Q5VWC4_HUMAN" 4 928.4642 1.55 28419 12133 2 928.461687 465.2394 26S proteasome non-ATPase regulatory subunit 4 OS=Homo sapiens OX=9606 GN=PSMD4 PE=1 SV=1 5.84 2464 - 1.72E+06 - - - -2.7066 - 1.959 0.537 - 363.6 1 2 0 -0.0025 8 0 0 0 1.83E+08 1.18E+08 - - - 5.0345 0.9952 221125_WJC_METTL3_EV_vs_WT_F03.12134.12134.2 0.359 12-Jul R.SLADFEK[136.11].A sp|O00231|PSD11_HUMAN 1 816.4109 0.71 28420 12134 2 816.409212 409.2127 26S proteasome non-ATPase regulatory subunit 11 OS=Homo sapiens OX=9606 GN=PSMD11 PE=1 SV=3 4.37 2464.1 - 557899 - - - -2.048 - 1.366 0.23 - 136.1 1 2 0 -0.0017 7 0 0 0 2.32E+07 3.26E+07 - - - 1.7275 0.9991 221125_WJC_METTL3_EV_vs_WT_F03.12136.12136.2 0.000276 16-Oct R.LPENLYNDR[166.11].M "sp|P14927|QCR7_HUMAN,tr|E5RHG9|E5RHG9_HUMAN,tr|B7Z2R2|B7Z2R2_HUMAN" 3 1142.5596 5.36 28422 12136 2 1142.556355 572.2871 Cytochrome b-c1 complex subunit 7 OS=Homo sapiens OX=9606 GN=UQCRB PE=1 SV=2 4.37 2464.4 - 497442 - - - -2.8025 - 1.954 0.4 - 329.1 1 2 0 -0.0032 9 0 0 0 1.07E+08 2.00E+07 - - - 3.9324 0.9377 221125_WJC_METTL3_EV_vs_WT_F03.12140.12140.2 2.57 14-Jun K.SLSLLASR.Y "sp|Q8IV33|K0825_HUMAN,tr|A0A804HHT9|A0A804HHT9_HUMAN" 2 845.4971 26.04 28424 12140 2 845.496487 423.7558 Uncharacterized protein KIAA0825 OS=Homo sapiens OX=9606 GN=KIAA0825 PE=1 SV=3 9.47 2464.8 - 6.06E+06 - - - -0.686 - 1.219 0.005 - 95.8 3 2 0 -0.0006 8 0 0 0 4.77E+08 1.83E+07 - - - -0.5381 0.9957 221125_WJC_METTL3_EV_vs_WT_F03.12141.12141.2 0.0672 16-Oct K.ISLAPTDVK.E "sp|Q8WWM7|ATX2L_HUMAN,tr|H3BUF6|H3BUF6_HUMAN" 2 942.5386 1.33 28425 12141 2 942.535971 472.2766 Ataxin-2-like protein OS=Homo sapiens OX=9606 GN=ATXN2L PE=1 SV=2 5.84 2464.9 - 4.05E+06 - - - -2.7861 - 1.802 0.206 - 260.7 1 2 0 -0.0026 9 0 0 0 2.13E+08 1.60E+08 - - - 2.2654 0.9993 221125_WJC_METTL3_EV_vs_WT_F03.12142.12142.2 0.0192 18-Sep R.VEPFVC[160.03]AQC[160.03]R.T "sp|Q8WXI9|P66B_HUMAN,tr|A0A0U1RRM1|A0A0U1RRM1_HUMAN,tr|A0A0U1RR30|A0A0U1RR30_HUMAN" 3 1264.5693 1.69 28426 12142 2 1264.565418 633.2919 Transcriptional repressor p66-beta OS=Homo sapiens OX=9606 GN=GATAD2B PE=1 SV=1 5.96 2465 - 1.20E+06 - - - -3.0406 - 1.884 0.508 - 427.7 1 2 0 -0.0038 10 0 0 0 2.82E+08 1.67E+08 - - - 4.5599 1 221125_WJC_METTL3_EV_vs_WT_F03.12143.12143.3 3.00E-10 16/64 R.AQVQEFC[160.03]DYGTK[136.11]EEC[160.03]MK[136.11].A "sp|Q86U44|MTA70_HUMAN,tr|H0YFV6|H0YFV6_HUMAN" 2 2137.909 0.001 28427 12143 3 2137.909579 713.6436 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 4.41 2465.1 - 556268 - - - 0.2881 - 3.035 0.678 - 228.1 1 2 1 0.0006 17 0 0 0 0.00E+00 2.07E+07 - - - 8.9036 0.9888 221125_WJC_METTL3_EV_vs_WT_F03.12150.12150.2 0.259 14-Jun K.DLDFAQQK.L "sp|Q8IX01|SUGP2_HUMAN,tr|M0R2Z9|M0R2Z9_HUMAN" 2 963.4662 9.81 28432 12150 2 963.468605 482.7404 SURP and G-patch domain-containing protein 2 OS=Homo sapiens OX=9606 GN=SUGP2 PE=1 SV=2 4.21 2466.1 - 569874 - - - 2.5367 - 1.175 0.27 - 83.3 2 2 0 0.0024 8 0 0 0 2.33E+08 2.38E+07 - - - 1.3864 0.9995 221125_WJC_METTL3_EV_vs_WT_F03.12154.12154.2 0.0427 16-Sep K.LSDGVAVLK[136.11].V "sp|P10809|CH60_HUMAN,tr|A0A7I2V2X6|A0A7I2V2X6_HUMAN,tr|A0A7I2YQK6|A0A7I2YQK6_HUMAN,tr|A0A7I2V599|A0A7I2V599_HUMAN" 4 908.5422 1.25 28434 12154 2 908.540864 455.2784 "60 kDa heat shock protein, mitochondrial OS=Homo sapiens OX=9606 GN=HSPD1 PE=1 SV=2" 5.84 2466.6 - 1.34E+07 - - - -1.5068 - 1.85 0.348 - 182.6 1 2 0 -0.0014 9 0 0 0 9.39E+08 7.53E+08 - - - 3.3907 0.9994 221125_WJC_METTL3_EV_vs_WT_F03.12155.12155.2 0.0236 20-Sep K.ATAVMPDGQFK.D "sp|Q06830|PRDX1_HUMAN,tr|A0A0A0MSI0|A0A0A0MSI0_HUMAN" 2 1163.5645 0.67 28435 12155 2 1163.562191 582.7895 Peroxiredoxin-1 OS=Homo sapiens OX=9606 GN=PRDX1 PE=1 SV=1 5.88 2466.7 - 1.58E+06 - - - -1.9801 - 1.847 0.402 - 235.9 1 2 0 -0.0023 11 0 0 0 4.77E+08 7.11E+08 - - - 3.6693 0.9935 221125_WJC_METTL3_EV_vs_WT_F03.12156.12156.2 3.63 18-Aug R.QIILSHFEDK[136.11].Q sp|Q14191|WRN_HUMAN 1 1236.6594 0.02 28436 12156 2 1236.656636 619.337 Werner syndrome ATP-dependent helicase OS=Homo sapiens OX=9606 GN=WRN PE=1 SV=2 5.32 2466.8 - 872792 - - - -2.2254 - 1.681 0.15 - 214.1 1 2 0 -0.0028 10 0 0 0 7.57E+05 3.83E+07 - - - 1.5978 0.9999 221125_WJC_METTL3_EV_vs_WT_F03.12158.12158.2 3.15E-05 18-Nov K.VEGELEEMER[166.11].K sp|P35580|MYH10_HUMAN 1 1229.5473 0.91 28438 12158 2 1229.546658 615.7809 Myosin-10 OS=Homo sapiens OX=9606 GN=MYH10 PE=1 SV=3 3.98 2467.1 - 657420 - - - -0.553 - 2.218 0.584 - 495.8 1 2 0 -0.0007 10 0 0 0 4.87E+07 5.37E+07 - - - 5.5778 0.9994 221125_WJC_METTL3_EV_vs_WT_F03.12159.12159.2 2.44E-05 18-Nov K.VEGELEEMER.K sp|P35580|MYH10_HUMAN 1 1219.5391 0.92 28439 12159 2 1219.53561 610.7768 Myosin-10 OS=Homo sapiens OX=9606 GN=MYH10 PE=1 SV=3 3.98 2467.2 - 540579 - - - -2.8355 - 1.967 0.492 - 517.8 1 2 0 -0.0035 10 0 0 0 4.87E+07 5.30E+07 - - - 4.5622 0.9998 221125_WJC_METTL3_EV_vs_WT_F03.12162.12162.2 2.54E-05 18-Nov R.SAYNVYVAER[166.11].F "sp|Q00059|TFAM_HUMAN,tr|H7BYN3|H7BYN3_HUMAN" 2 1180.5752 3.11 28441 12162 2 1180.573398 591.2949 "Transcription factor A, mitochondrial OS=Homo sapiens OX=9606 GN=TFAM PE=1 SV=1" 5.72 2467.5 - 3.23E+06 - - - -1.5323 - 2.055 0.53 - 411.3 1 2 0 -0.0018 10 0 0 0 3.64E+08 1.17E+08 - - - 4.9655 0.9999 221125_WJC_METTL3_EV_vs_WT_F03.12163.12163.3 0.000247 14/36 K.AFADPEVLRR.L "sp|O75179|ANR17_HUMAN,sp|Q8IWZ3|ANKH1_HUMAN,tr|E9PDP5|E9PDP5_HUMAN,tr|H0YM23|H0YM23_HUMAN,tr|A0A1W2PQ15|A0A1W2PQ15_HUMAN" 5 1172.6302 1.41 28442 12163 3 1172.628015 391.884 Ankyrin repeat domain-containing protein 17 OS=Homo sapiens OX=9606 GN=ANKRD17 PE=1 SV=3 6.12 2467.6 - 1.84E+06 - - - -1.8684 - 2.4 0.446 - 231.5 1 2 0 -0.0022 10 0 0 0 3.44E+07 2.44E+07 - - - 6.0686 0.9997 221125_WJC_METTL3_EV_vs_WT_F03.12165.12165.2 0.000245 22-Dec K.VAVVAGYGDVGK[136.11].G sp|P23526|SAHH_HUMAN 1 1141.6223 0.26 28444 12165 2 1141.624682 571.8184 Adenosylhomocysteinase OS=Homo sapiens OX=9606 GN=AHCY PE=1 SV=4 5.81 2467.9 - 783419 - - - 2.1093 - 2.423 0.479 - 522.4 1 2 0 0.0024 12 0 0 0 2.88E+07 1.13E+08 - - - 4.9067 0.8988 221125_WJC_METTL3_EV_vs_WT_F03.12167.12167.2 0.341 18-Aug K.SGIISEPLNK[136.11].S "sp|Q7LFL8|CXXC5_HUMAN,tr|E7EVI8|E7EVI8_HUMAN,tr|D6RHG9|D6RHG9_HUMAN,tr|D6RIR8|D6RIR8_HUMAN,tr|D6R966|D6R966_HUMAN,tr|D6RHC6|D6RHC6_HUMAN,tr|E7EV55|E7EV55_HUMAN,tr|D6RDY2|D6RDY2_HUMAN,tr|D6RBE0|D6RBE0_HUMAN,tr|D6R9V1|D6R9V1_HUMAN" 10 1064.5957 1.52 28446 12167 2 1064.593279 533.3051 CXXC-type zinc finger protein 5 OS=Homo sapiens OX=9606 GN=CXXC5 PE=1 SV=1 5.72 2468.1 - 579317 - - - -2.2976 - 1.312 0.005 - 107.6 2 2 0 -0.0024 10 0 0 0 1.57E+07 1.03E+07 - - - -0.2993 0.9998 221125_WJC_METTL3_EV_vs_WT_F03.12171.12171.2 1.15E-05 18-Sep R.VEPFVC[160.03]AQC[160.03]R[166.11].T "sp|Q8WXI9|P66B_HUMAN,tr|A0A0U1RRM1|A0A0U1RRM1_HUMAN,tr|A0A0U1RR30|A0A0U1RR30_HUMAN" 3 1274.5775 1.7 28448 12171 2 1274.575767 638.296 Transcriptional repressor p66-beta OS=Homo sapiens OX=9606 GN=GATAD2B PE=1 SV=1 5.96 2468.5 - 3.73E+06 - - - -1.3856 - 1.883 0.51 - 408.8 1 2 0 -0.0018 10 0 0 0 2.83E+08 1.67E+08 - - - 4.5738 0.9804 221125_WJC_METTL3_EV_vs_WT_F03.12172.12172.2 0.0143 16-Sep F.AAQELIEVK[136.11].R "sp|Q86U44|MTA70_HUMAN,tr|F5H6D8|F5H6D8_HUMAN,tr|H0YFV6|H0YFV6_HUMAN,tr|B4DTN4|B4DTN4_HUMAN" 4 1007.5743 0.02 28449 12172 2 1007.57365 504.7944 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 4.53 2468.6 - 3.31E+06 - - - -0.6064 - 1.994 0.335 - 388.3 1 1 0 -0.0006 9 0 0 0 1.77E+07 9.36E+08 - - - 3.5117 0.7748 221125_WJC_METTL3_EV_vs_WT_F03.12174.12174.2 0.201 14-Jul P.VTLELGGK.N "sp|P43353|AL3B1_HUMAN,sp|P30838|AL3A1_HUMAN,sp|P00352|AL1A1_HUMAN,sp|P48448|AL3B2_HUMAN,sp|P05091|ALDH2_HUMAN,sp|P51648|AL3A2_HUMAN,sp|P49189|AL9A1_HUMAN,sp|P30837|AL1B1_HUMAN,sp|P47895|AL1A3_HUMAN,sp|O94788|AL1A2_HUMAN,tr|E9PNN6|E9PNN6_HUMAN,tr|I3L1M4|I3L1M4_HUMAN,tr|A0A5F9ZHI5|A0A5F9ZHI5_HUMAN,tr|H0Y2X5|H0Y2X5_HUMAN,tr|I3L3I9|I3L3I9_HUMAN,tr|A0A5F9ZI12|A0A5F9ZI12_HUMAN,tr|E9PJV0|E9PJV0_HUMAN,tr|A0A5F9ZHZ9|A0A5F9ZHZ9_HUMAN,tr|J3QS00|J3QS00_HUMAN,tr|A0A5F9ZHN9|A0A5F9ZHN9_HUMAN,tr|C9JMC5|C9JMC5_HUMAN,tr|C9JKT2|C9JKT2_HUMAN,tr|H0YMG7|H0YMG7_HUMAN,tr|A0A5F9ZGX4|A0A5F9ZGX4_HUMAN,tr|A8MYB8|A8MYB8_HUMAN,tr|J3QRD1|J3QRD1_HUMAN" 26 815.4753 1.14 28451 12174 2 815.474489 408.7449 Aldehyde dehydrogenase family 3 member B1 OS=Homo sapiens OX=9606 GN=ALDH3B1 PE=1 SV=1 5.97 2468.7 - 1.73E+06 - - - -0.9565 - 1.308 0.189 - 110.4 1 1 0 -0.0008 8 0 0 0 5.84E+07 5.10E+07 - - - 1.2465 0.9908 221125_WJC_METTL3_EV_vs_WT_F03.12175.12175.2 0.405 12-Jun R.GYSSLLK[136.11].R "sp|P17844|DDX5_HUMAN,tr|J3KTA4|J3KTA4_HUMAN,tr|A0A0G2JLI4|A0A0G2JLI4_HUMAN" 3 774.4367 1.73 28452 12175 2 774.436503 388.2256 Probable ATP-dependent RNA helicase DDX5 OS=Homo sapiens OX=9606 GN=DDX5 PE=1 SV=1 8.59 2468.9 - 1.03E+06 - - - -0.2608 - 1.08 0.188 - 127 1 2 0 -0.0002 7 0 0 0 7.35E+07 4.26E+07 - - - 0.6734 0.993 221125_WJC_METTL3_EV_vs_WT_F03.12179.12179.2 0.00162 16-Nov K.DVFR[166.11]DPALK[136.11].R "sp|P61353|RL27_HUMAN,tr|K7ELC7|K7ELC7_HUMAN" 2 1077.5938 0.85 28454 12179 2 1077.593725 539.8042 60S ribosomal protein L27 OS=Homo sapiens OX=9606 GN=RPL27 PE=1 SV=2 5.96 2469.4 - 1.37E+06 - - - -0.0371 - 2.44 0.158 - 548.8 1 2 1 0 9 0 0 0 3.22E+07 3.80E+07 - - - 2.7886 0.9274 221125_WJC_METTL3_EV_vs_WT_F03.12180.12180.2 0.0299 18-Aug R.FVSEAELDER[166.11].R "sp|Q9GZU8|PIP30_HUMAN,tr|H3BP64|H3BP64_HUMAN,tr|H3BSF0|H3BSF0_HUMAN,tr|H3BTP8|H3BTP8_HUMAN,tr|H3BPH9|H3BPH9_HUMAN,tr|H3BPF9|H3BPF9_HUMAN,tr|H3BMX9|H3BMX9_HUMAN,tr|H3BQQ6|H3BQQ6_HUMAN,tr|H3BN22|H3BN22_HUMAN,tr|Q6P4H7|Q6P4H7_HUMAN,tr|H3BTI2|H3BTI2_HUMAN,tr|H3BUL4|H3BUL4_HUMAN,tr|H3BSY6|H3BSY6_HUMAN" 13 1203.5647 0.01 28455 12180 2 1203.56943 602.7896 PSME3-interacting protein OS=Homo sapiens OX=9606 GN=PSME3IP1 PE=1 SV=1 4 2469.5 - 685208 - - - 3.9283 - 1.439 0.109 - 154.9 2 2 0 0.0047 10 0 0 0 1.38E+05 1.35E+07 - - - 0.726 0.998 221125_WJC_METTL3_EV_vs_WT_F03.12182.12182.2 0.161 12-Jul R.SLADFEK.A sp|O00231|PSD11_HUMAN 1 808.3967 0.78 28457 12182 2 808.39567 405.2056 26S proteasome non-ATPase regulatory subunit 11 OS=Homo sapiens OX=9606 GN=PSMD11 PE=1 SV=3 4.37 2469.8 - 991990 - - - -1.2543 - 1.411 0.255 - 163.7 1 2 0 -0.001 7 0 0 0 2.47E+07 3.15E+07 - - - 2.015 0.9995 221125_WJC_METTL3_EV_vs_WT_F03.12183.12183.2 0.000251 22-Aug K.YYADGEDAYAMK[136.11].R "sp|Q9BSU3|NAA11_HUMAN,sp|P41227|NAA10_HUMAN,tr|A8MWP7|A8MWP7_HUMAN,tr|F8W808|F8W808_HUMAN,tr|C9JW55|C9JW55_HUMAN,tr|H0Y8T0|H0Y8T0_HUMAN,tr|C9JN83|C9JN83_HUMAN" 7 1403.5795 0.62 28458 12183 2 1403.580771 702.797 N-alpha-acetyltransferase 11 OS=Homo sapiens OX=9606 GN=NAA11 PE=1 SV=3 4.03 2469.9 - 604485 - - - 0.9177 - 1.41 0.458 - 96.6 1 2 0 0.0013 12 0 0 0 8.02E+06 1.30E+07 - - - 3.3274 0.9995 221125_WJC_METTL3_EV_vs_WT_F03.12184.12184.2 0.000436 18-Oct R.ALEQQVEEMK[136.11].T sp|P35579|MYH9_HUMAN 1 1211.5947 1.28 28459 12184 2 1211.592441 606.8046 Myosin-9 OS=Homo sapiens OX=9606 GN=MYH9 PE=1 SV=4 4.25 2470 - 345669 - - - -1.8967 - 2.072 0.385 - 334.9 1 2 0 -0.0023 10 0 0 0 2.41E+08 1.89E+08 - - - 3.9174 0.9999 221125_WJC_METTL3_EV_vs_WT_F03.12186.12186.2 9.38E-05 18-Nov K.VPSSTVEYLK[136.11].K "sp|Q9H7C9|AAMDC_HUMAN,tr|E9PNP3|E9PNP3_HUMAN,tr|E9PR47|E9PR47_HUMAN,tr|E9PIQ4|E9PIQ4_HUMAN" 4 1129.611 1.5 28460 12186 2 1129.610903 565.8128 Mth938 domain-containing protein OS=Homo sapiens OX=9606 GN=AAMDC PE=1 SV=1 5.97 2470.3 - 5.90E+06 - - - -0.1222 - 2.234 0.508 - 593.9 1 2 0 -0.0001 10 0 0 0 2.99E+08 1.99E+08 - - - 5.0367 0.9998 221125_WJC_METTL3_EV_vs_WT_F03.12188.12188.2 6.23E-05 18-Sep K.VPSSTVEYLK.K "sp|Q9H7C9|AAMDC_HUMAN,tr|E9PNP3|E9PNP3_HUMAN,tr|E9PR47|E9PR47_HUMAN,tr|E9PIQ4|E9PIQ4_HUMAN" 4 1121.5968 1.52 28461 12188 2 1121.596999 561.8057 Mth938 domain-containing protein OS=Homo sapiens OX=9606 GN=AAMDC PE=1 SV=1 5.97 2470.5 - 1.06E+07 - - - 0.1409 - 2.207 0.389 - 366.5 1 2 0 0.0002 10 0 0 0 2.98E+08 1.97E+08 - - - 4.1238 0.9986 221125_WJC_METTL3_EV_vs_WT_F03.12189.12189.2 0.134 14-Oct R.LAELSDYR[166.11].R sp|Q96PK6|RBM14_HUMAN 1 975.4901 2.06 28462 12189 2 975.490354 488.7523 RNA-binding protein 14 OS=Homo sapiens OX=9606 GN=RBM14 PE=1 SV=2 4.37 2470.6 - 1.51E+06 - - - 0.2799 - 1.699 0.2 - 398.9 1 2 0 0.0003 8 0 0 0 2.15E+08 1.04E+08 - - - 2.1167 0.9993 221125_WJC_METTL3_EV_vs_WT_F03.12191.12191.2 0.177 18-Nov K.LGNEVGYSIR.F "sp|O60231|DHX16_HUMAN,tr|A0A140T947|A0A140T947_HUMAN" 2 1106.572 0.53 28464 12191 2 1106.570012 554.2933 Pre-mRNA-splicing factor ATP-dependent RNA helicase DHX16 OS=Homo sapiens OX=9606 GN=DHX16 PE=1 SV=2 6 2470.8 - 1.04E+06 - - - -1.8173 - 2.302 0.262 - 348 1 2 0 -0.002 10 0 0 0 4.19E+07 7.96E+07 - - - 3.3028 0.9927 221125_WJC_METTL3_EV_vs_WT_F03.12192.12192.2 1.59 14-Jun K.EILSEVER[166.11].N "sp|P49368|TCPG_HUMAN,tr|B4DUR8|B4DUR8_HUMAN" 2 983.5163 0.23 28465 12192 2 983.516487 492.7654 T-complex protein 1 subunit gamma OS=Homo sapiens OX=9606 GN=CCT3 PE=1 SV=4 4.25 2470.9 - 893381 - - - 0.1942 - 1.387 0.111 - 133.6 1 2 0 0.0002 8 0 0 0 2.31E+08 1.02E+09 - - - 0.8474 0.9998 221125_WJC_METTL3_EV_vs_WT_F03.12195.12195.2 0.00873 14-Aug R.QFC[160.03]TGEFR.K "sp|O43447|PPIH_HUMAN,tr|A0A7I2V2H6|A0A7I2V2H6_HUMAN,tr|A0A7I2V343|A0A7I2V343_HUMAN,tr|A0A7I2V5V0|A0A7I2V5V0_HUMAN,tr|A0A7I2YQS4|A0A7I2YQS4_HUMAN,tr|C9JQD4|C9JQD4_HUMAN" 6 1043.4495 2.33 28466 12195 2 1043.448258 522.732 Peptidyl-prolyl cis-trans isomerase H OS=Homo sapiens OX=9606 GN=PPIH PE=1 SV=1 5.99 2471.3 - 1.84E+06 - - - -1.1567 - 1.603 0.505 - 371.5 1 2 0 -0.0012 8 0 0 0 7.25E+07 3.12E+07 - - - 4.1937 0.9998 221125_WJC_METTL3_EV_vs_WT_F03.12196.12196.2 7.62E-05 14-Sep R.QFC[160.03]TGEFR[166.11].K "sp|O43447|PPIH_HUMAN,tr|A0A7I2V2H6|A0A7I2V2H6_HUMAN,tr|A0A7I2V343|A0A7I2V343_HUMAN,tr|A0A7I2V5V0|A0A7I2V5V0_HUMAN,tr|A0A7I2YQS4|A0A7I2YQS4_HUMAN,tr|C9JQD4|C9JQD4_HUMAN" 6 1053.4577 2.35 28467 12196 2 1053.456909 527.7361 Peptidyl-prolyl cis-trans isomerase H OS=Homo sapiens OX=9606 GN=PPIH PE=1 SV=1 5.99 2471.4 - 1.09E+06 - - - -0.7841 - 1.708 0.452 - 450 1 2 0 -0.0008 8 0 0 0 7.40E+07 3.14E+07 - - - 3.9937 0.9993 221125_WJC_METTL3_EV_vs_WT_F03.12199.12199.2 0.0161 14-Oct R.QTLAIYDR[166.11].F "sp|Q9BRJ2|RM45_HUMAN,tr|A0A087X2D5|A0A087X2D5_HUMAN" 2 988.5217 1.02 28470 12199 2 988.523585 495.2681 "39S ribosomal protein L45, mitochondrial OS=Homo sapiens OX=9606 GN=MRPL45 PE=1 SV=2" 5.84 2471.7 - 630002 - - - 1.8917 - 1.995 0.318 - 328.8 1 2 0 0.0019 8 0 0 0 2.22E+07 2.17E+07 - - - 3.4721 0.9993 221125_WJC_METTL3_EV_vs_WT_F03.12203.12203.2 0.448 14-Sep K.SIELESVR.G "sp|P07197|NFM_HUMAN,tr|E7ESP9|E7ESP9_HUMAN,tr|E7EMV2|E7EMV2_HUMAN" 3 931.4975 2.27 28472 12203 2 931.497607 466.756 Neurofilament medium polypeptide OS=Homo sapiens OX=9606 GN=NEFM PE=1 SV=3 4.53 2472.1 - 4.07E+06 - - - 0.1567 - 1.678 0.293 - 273.5 1 2 0 0.0001 8 0 0 0 1.98E+08 8.76E+07 - - - 2.7661 0.9992 221125_WJC_METTL3_EV_vs_WT_F03.12205.12205.2 1.04 16-Aug K.LIIVEGC[160.03]QR[166.11].Q "sp|P05023|AT1A1_HUMAN,sp|P13637|AT1A3_HUMAN,sp|Q13733|AT1A4_HUMAN,sp|P50993|AT1A2_HUMAN,sp|P54707|AT12A_HUMAN,tr|A0A0A0MT26|A0A0A0MT26_HUMAN,tr|H0Y7C1|H0Y7C1_HUMAN,tr|A0A2R8YEY8|A0A2R8YEY8_HUMAN,tr|B1AKY9|B1AKY9_HUMAN,tr|M0R116|M0R116_HUMAN" 10 1096.5938 1.13 28474 12205 2 1096.594427 549.3042 Sodium\potassium-transporting ATPase subunit alpha-1 OS=Homo sapiens OX=9606 GN=ATP1A1 PE=1 SV=1 5.99 2472.3 - 1.32E+06 - - - 0.5399 - 1.773 0.263 - 183.1 1 2 0 0.0006 9 0 0 0 3.48E+07 3.08E+07 - - - 2.6401 0.9994 221125_WJC_METTL3_EV_vs_WT_F03.12210.12210.2 0.0196 18-Aug K.VQSLQTALEK.T "sp|Q13948|CASP_HUMAN,sp|P39880|CUX1_HUMAN,tr|A0A2R8Y8D0|A0A2R8Y8D0_HUMAN,tr|A0A2R8Y852|A0A2R8Y852_HUMAN,tr|A0A2R8YDI1|A0A2R8YDI1_HUMAN" 5 1115.6186 1.46 28477 12210 2 1115.617696 558.8166 Protein CASP OS=Homo sapiens OX=9606 GN=CUX1 PE=1 SV=2 5.97 2472.9 - 9.85E+06 - - - -0.8453 - 1.871 0.299 - 264.3 1 2 0 -0.0009 10 0 0 0 2.21E+08 1.52E+08 - - - 2.9978 0.9993 221125_WJC_METTL3_EV_vs_WT_F03.12212.12212.2 0.0173 18-Sep R.ASVSQAVFAR.V "sp|Q9UPW6|SATB2_HUMAN,tr|C9JR56|C9JR56_HUMAN" 2 1034.5509 1.65 28479 12212 2 1034.5517 518.2827 DNA-binding protein SATB2 OS=Homo sapiens OX=9606 GN=SATB2 PE=1 SV=2 9.79 2473 - 2.44E+06 - - - 0.78 - 1.595 0.34 - 256.9 1 2 0 0.0008 10 0 0 0 4.69E+07 2.85E+07 - - - 2.8552 0.9884 221125_WJC_METTL3_EV_vs_WT_F03.12214.12214.2 0.154 18-Jul K.ATSTSDMLLK.L "sp|Q9NW64|RBM22_HUMAN,tr|E5RJW4|E5RJW4_HUMAN" 2 1065.5376 1.22 28481 12214 2 1065.537099 533.7761 Pre-mRNA-splicing factor RBM22 OS=Homo sapiens OX=9606 GN=RBM22 PE=1 SV=1 5.88 2473.1 - 836395 - - - -0.4805 - 1.396 0.076 - 112.4 1 2 0 -0.0005 10 0 0 0 4.38E+07 3.59E+07 - - - 0.5334 0.9998 221125_WJC_METTL3_EV_vs_WT_F03.12216.12216.2 5.18E-06 20-Nov R.YITQNGDYQLR.T "sp|Q9BXS5|AP1M1_HUMAN,tr|E7ENJ6|E7ENJ6_HUMAN,tr|K7EJL1|K7EJL1_HUMAN" 3 1369.6626 0.88 28483 12216 2 1369.662222 685.8386 AP-1 complex subunit mu-1 OS=Homo sapiens OX=9606 GN=AP1M1 PE=1 SV=3 5.83 2473.4 - 333174 - - - -0.2972 - 1.84 0.442 - 395.9 1 2 0 -0.0004 11 0 0 0 1.32E+07 1.49E+07 - - - 3.955 0.9997 221125_WJC_METTL3_EV_vs_WT_F03.12218.12218.2 0.0135 18-Nov R.VNLSAAQTLR[166.11].A "sp|Q9BUL8|PDC10_HUMAN,tr|C9J932|C9J932_HUMAN,tr|C9J5C3|C9J5C3_HUMAN,tr|F8WDF3|F8WDF3_HUMAN,tr|C9JSA3|C9JSA3_HUMAN,tr|C9J6F3|C9J6F3_HUMAN,tr|H7C5M9|H7C5M9_HUMAN,tr|C9JND6|C9JND6_HUMAN" 8 1081.6119 0.72 28484 12218 2 1081.612045 541.8132 Programmed cell death protein 10 OS=Homo sapiens OX=9606 GN=PDCD10 PE=1 SV=1 9.72 2473.6 - 1.33E+06 - - - 0.1091 - 2.148 0.31 - 534.1 1 2 0 0.0001 10 0 0 0 2.41E+07 3.32E+07 - - - 3.4647 0.9998 221125_WJC_METTL3_EV_vs_WT_F03.12220.12220.2 4.91E-05 16-Sep R.VEFMDDTSR.S sp|P62857|RS28_HUMAN 1 1098.4652 1.01 28485 12220 2 1098.464566 550.2399 40S ribosomal protein S28 OS=Homo sapiens OX=9606 GN=RPS28 PE=1 SV=1 4.03 2473.8 - 2.60E+06 - - - -0.5535 - 1.834 0.425 - 324.7 1 2 0 -0.0006 9 0 0 0 6.45E+08 6.36E+08 - - - 3.9345 0.9993 221125_WJC_METTL3_EV_vs_WT_F03.12221.12221.3 0.0331 Nov-36 R.LLHDLQIGEK[136.11].K "sp|P49756|RBM25_HUMAN,tr|E9PQU5|E9PQU5_HUMAN" 2 1172.6645 0.87 28486 12221 3 1172.665229 391.8954 RNA-binding protein 25 OS=Homo sapiens OX=9606 GN=RBM25 PE=1 SV=3 5.32 2473.9 - 1.11E+06 - - - 0.6447 - 1.934 0.279 - 141.5 1 2 0 0.0008 10 0 0 0 3.40E+07 3.91E+07 - - - 3.5767 0.9998 221125_WJC_METTL3_EV_vs_WT_F03.12222.12222.2 0.0156 14-Sep R.NGDFLPTR.L "sp|P55036|PSMD4_HUMAN,sp|A2A3N6|PIPSL_HUMAN,tr|A6PVX3|A6PVX3_HUMAN,tr|Q5VWC4|Q5VWC4_HUMAN" 4 918.4559 1.57 28487 12222 2 918.45568 460.2352 26S proteasome non-ATPase regulatory subunit 4 OS=Homo sapiens OX=9606 GN=PSMD4 PE=1 SV=1 5.84 2474 - 4.30E+06 - - - -0.2722 - 1.893 0.384 - 451.4 1 2 0 -0.0003 8 0 0 0 1.85E+08 1.18E+08 - - - 3.8018 0.9446 221125_WJC_METTL3_EV_vs_WT_F03.12223.12223.2 0.0169 18-Oct Y.FTSGLQAGLK[136.11].Q "sp|Q8IY67|RAVR1_HUMAN,tr|K7EQG2|K7EQG2_HUMAN,tr|E9PAU2|E9PAU2_HUMAN,tr|A0A087WZ13|A0A087WZ13_HUMAN" 4 1028.5746 0.53 28488 12223 2 1028.577036 515.2946 Ribonucleoprotein PTB-binding 1 OS=Homo sapiens OX=9606 GN=RAVER1 PE=1 SV=1 8.75 2474 - 1.23E+06 - - - 2.3732 - 1.765 0.385 - 251.7 1 1 0 0.0024 10 0 0 0 1.80E+07 3.36E+07 - - - 3.4697 0.9999 221125_WJC_METTL3_EV_vs_WT_F03.12225.12225.2 1.29E-06 24-Dec K.LESLEETNPEYAK.L sp|Q5VUA4|ZN318_HUMAN 1 1521.7199 1.2 28490 12225 2 1521.72079 761.8672 Zinc finger protein 318 OS=Homo sapiens OX=9606 GN=ZNF318 PE=1 SV=2 4.09 2474.3 - 278312 - - - 0.6052 - 2.341 0.533 - 568.2 1 2 0 0.0009 13 0 0 0 1.46E+07 1.22E+07 - - - 5.1605 0.9921 221125_WJC_METTL3_EV_vs_WT_F03.12228.12228.2 0.351 14-Aug K.SIELESVR[166.11].G "sp|P07197|NFM_HUMAN,tr|E7ESP9|E7ESP9_HUMAN,tr|E7EMV2|E7EMV2_HUMAN" 3 941.5057 2.24 28491 12228 2 941.502311 471.7601 Neurofilament medium polypeptide OS=Homo sapiens OX=9606 GN=NEFM PE=1 SV=3 4.53 2474.7 - 3.81E+06 - - - -3.6325 - 1.574 0.252 - 208.7 1 2 0 -0.0034 8 0 0 0 1.99E+08 8.86E+07 - - - 2.2693 0.9984 221125_WJC_METTL3_EV_vs_WT_F03.12229.12229.3 0.0204 Nov-36 R.LLHDLQIGEK.K "sp|P49756|RBM25_HUMAN,tr|E9PQU5|E9PQU5_HUMAN" 2 1164.6503 0.87 28492 12229 3 1164.64941 389.224 RNA-binding protein 25 OS=Homo sapiens OX=9606 GN=RBM25 PE=1 SV=3 5.32 2474.8 - 1.51E+06 - - - -0.741 - 1.728 0.257 - 108.6 1 2 0 -0.0009 10 0 0 0 3.40E+07 3.91E+07 - - - 3.0024 0.9999 221125_WJC_METTL3_EV_vs_WT_F03.12230.12230.2 3.51E-05 18-Sep R.VMEIVDADEK[136.11].V sp|Q9Y5B9|SP16H_HUMAN 1 1155.5573 -1 28493 12230 2 1155.558434 578.7859 FACT complex subunit SPT16 OS=Homo sapiens OX=9606 GN=SUPT16H PE=1 SV=1 3.92 2474.9 - 1.61E+06 - - - 0.9891 - 2.39 0.535 - 273.2 1 2 0 0.0011 10 0 0 0 0.00E+00 0.00E+00 - - - 5.4242 0.9999 221125_WJC_METTL3_EV_vs_WT_F03.12231.12231.2 5.35E-06 18-Oct R.VMEIVDADEK.V sp|Q9Y5B9|SP16H_HUMAN 1 1147.5431 0.44 28494 12231 2 1147.541768 574.7788 FACT complex subunit SPT16 OS=Homo sapiens OX=9606 GN=SUPT16H PE=1 SV=1 3.92 2474.9 - 1.00E+06 - - - -1.1529 - 2.172 0.533 - 368.4 1 2 0 -0.0013 10 0 0 0 6.40E+07 1.44E+08 - - - 5.1424 0.9994 221125_WJC_METTL3_EV_vs_WT_F03.12234.12234.2 2.93E-06 24-Sep K.AVYTQDC[160.03]PLAAAK.A "sp|P49588|SYAC_HUMAN,tr|A0A6Q8PGR9|A0A6Q8PGR9_HUMAN,tr|A0A6Q8PFY2|A0A6Q8PFY2_HUMAN,tr|A0A6Q8PFK3|A0A6Q8PFK3_HUMAN,tr|H3BPK7|H3BPK7_HUMAN,tr|A0A6Q8PHJ2|A0A6Q8PHJ2_HUMAN,tr|A0A6Q8PGB5|A0A6Q8PGB5_HUMAN,tr|A0A6Q8PGE8|A0A6Q8PGE8_HUMAN,tr|A0A6Q8PF33|A0A6Q8PF33_HUMAN,tr|A0A6Q8PGN5|A0A6Q8PGN5_HUMAN" 10 1406.6864 1.19 28497 12234 2 1406.688454 704.3505 "Alanine--tRNA ligase, cytoplasmic OS=Homo sapiens OX=9606 GN=AARS1 PE=1 SV=2" 5.87 2475.4 - 311466 - - - 1.4595 - 1.652 0.411 - 140.5 1 2 0 0.0021 13 0 0 0 8.51E+06 7.17E+06 - - - 3.3644 0.9967 221125_WJC_METTL3_EV_vs_WT_F03.12235.12235.2 0.0433 24-Sep K.AVYTQDC[160.03]PLAAAK[136.11].A "sp|P49588|SYAC_HUMAN,tr|A0A6Q8PGR9|A0A6Q8PGR9_HUMAN,tr|A0A6Q8PFY2|A0A6Q8PFY2_HUMAN,tr|A0A6Q8PFK3|A0A6Q8PFK3_HUMAN,tr|H3BPK7|H3BPK7_HUMAN,tr|A0A6Q8PHJ2|A0A6Q8PHJ2_HUMAN,tr|A0A6Q8PGB5|A0A6Q8PGB5_HUMAN,tr|A0A6Q8PGE8|A0A6Q8PGE8_HUMAN,tr|A0A6Q8PF33|A0A6Q8PF33_HUMAN,tr|A0A6Q8PGN5|A0A6Q8PGN5_HUMAN" 10 1414.7006 1.19 28498 12235 2 1414.699517 708.3576 "Alanine--tRNA ligase, cytoplasmic OS=Homo sapiens OX=9606 GN=AARS1 PE=1 SV=2" 5.87 2475.5 - 240818 - - - -0.7662 - 1.32 0.233 - 54.4 1 2 0 -0.0011 13 0 0 0 8.51E+06 7.17E+06 - - - 1.4741 0.9959 221125_WJC_METTL3_EV_vs_WT_F03.12238.12238.2 0.685 14-Jun K.EILSEVER.N "sp|P49368|TCPG_HUMAN,tr|B4DUR8|B4DUR8_HUMAN" 2 973.508 0.22 28499 12238 2 973.508166 487.7613 T-complex protein 1 subunit gamma OS=Homo sapiens OX=9606 GN=CCT3 PE=1 SV=4 4.25 2475.9 - 8.11E+06 - - - 0.1438 - 1.302 0.192 - 134 1 2 0 0.0001 8 0 0 0 2.32E+08 1.03E+09 - - - 1.255 0.9998 221125_WJC_METTL3_EV_vs_WT_F03.12240.12240.2 0.000598 16-Sep K.QQLALYTEK.F sp|P40222|TXLNA_HUMAN 1 1092.5815 1.12 28501 12240 2 1092.582135 547.298 Alpha-taxilin OS=Homo sapiens OX=9606 GN=TXLNA PE=1 SV=3 6 2476 - 2.31E+06 - - - 0.5583 - 1.841 0.424 - 337.8 1 2 0 0.0006 9 0 0 0 5.37E+07 4.79E+07 - - - 3.9381 0.9993 221125_WJC_METTL3_EV_vs_WT_F03.12241.12241.2 0.113 14-Sep R.SPPIPYPR.S "sp|Q6W2J9|BCOR_HUMAN,tr|H7BZ37|H7BZ37_HUMAN,tr|A1A564|A1A564_HUMAN,tr|H7C2V9|H7C2V9_HUMAN,tr|H7BYY2|H7BYY2_HUMAN,tr|H7C231|H7C231_HUMAN" 6 925.5022 1.84 28502 12241 2 925.501348 463.7584 BCL-6 corepressor OS=Homo sapiens OX=9606 GN=BCOR PE=1 SV=1 8.46 2476 - 2.24E+06 - - - -0.8687 - 1.548 0.341 - 322.2 1 2 0 -0.0008 8 0 0 0 6.15E+07 3.34E+07 - - - 2.8772 0.9983 221125_WJC_METTL3_EV_vs_WT_F03.12243.12243.2 0.0231 24-Oct K.LESLEETNPEYAK[136.11].L sp|Q5VUA4|ZN318_HUMAN 1 1529.7341 1.2 28504 12243 2 1529.738997 765.8743 Zinc finger protein 318 OS=Homo sapiens OX=9606 GN=ZNF318 PE=1 SV=2 4.09 2476.2 - 475542 - - - 3.2215 - 2.083 0.352 - 346.5 1 2 0 0.0049 13 0 0 0 1.46E+07 1.22E+07 - - - 3.5227 0.998 221125_WJC_METTL3_EV_vs_WT_F03.12247.12247.2 0.117 20-Nov K.ALDGAFTEENR.A sp|Q9Y490|TLN1_HUMAN 1 1221.5626 1.26 28506 12247 2 1221.566327 611.7886 Talin-1 OS=Homo sapiens OX=9606 GN=TLN1 PE=1 SV=3 4.14 2476.8 - 1.40E+06 - - - 3.0674 - 1.951 0.318 - 362.9 1 2 0 0.0037 11 0 0 0 3.10E+07 2.47E+07 - - - 3.1966 0.9768 221125_WJC_METTL3_EV_vs_WT_F03.12248.12248.2 0.000174 16-Nov F.WAPESAPLK.S "sp|P23528|COF1_HUMAN,sp|Q9Y281|COF2_HUMAN,tr|E9PP50|E9PP50_HUMAN,tr|G3V1A4|G3V1A4_HUMAN,tr|E9PQB7|E9PQB7_HUMAN,tr|E9PK25|E9PK25_HUMAN" 6 997.5233 1.39 28507 12248 2 997.524593 499.7689 Cofilin-1 OS=Homo sapiens OX=9606 GN=CFL1 PE=1 SV=3 6 2476.8 - 1.53E+06 - - - 1.3143 - 1.984 0.372 - 452.3 1 1 0 0.0013 9 0 0 0 7.89E+07 5.68E+07 - - - 3.7703 0.9963 221125_WJC_METTL3_EV_vs_WT_F03.12249.12249.3 0.0556 Aug-32 K.YHTEIVFAR[166.11].T sp|P05023|AT1A1_HUMAN 1 1144.5905 0.03 28508 12249 3 1144.588963 382.5374 Sodium\potassium-transporting ATPase subunit alpha-1 OS=Homo sapiens OX=9606 GN=ATP1A1 PE=1 SV=1 6.75 2476.9 - 1.50E+06 - - - -1.3114 - 1.612 0.228 - 134.5 1 2 0 -0.0015 9 0 0 0 1.27E+06 3.74E+07 - - - 2.5206 0.9406 221125_WJC_METTL3_EV_vs_WT_F03.12251.12251.2 6.21 16-Aug K.APEPLSSLK[136.11].S "sp|O75175|CNOT3_HUMAN,tr|A0A2R8Y691|A0A2R8Y691_HUMAN,tr|B7Z6J7|B7Z6J7_HUMAN,tr|A0A2H2FJL5|A0A2H2FJL5_HUMAN,tr|H7C3F5|H7C3F5_HUMAN,tr|A0A2R8Y4W0|A0A2R8Y4W0_HUMAN,tr|H0Y5X7|H0Y5X7_HUMAN" 7 948.5371 1.6 28510 12251 2 948.538365 475.2758 CCR4-NOT transcription complex subunit 3 OS=Homo sapiens OX=9606 GN=CNOT3 PE=1 SV=1 6.05 2477.2 - 768775 - - - 1.2841 - 1.186 0.024 - 125 1 2 0 0.0012 9 0 0 0 2.41E+08 1.51E+08 - - - -0.2886 0.793 221125_WJC_METTL3_EV_vs_WT_F03.12257.12257.2 0.319 16-Aug K.LLHHLSDLA.L "sp|Q86U44|MTA70_HUMAN,tr|B4E349|B4E349_HUMAN,tr|F5H6D8|F5H6D8_HUMAN,tr|H0YFV6|H0YFV6_HUMAN,tr|B4DTN4|B4DTN4_HUMAN" 5 1017.5607 - 28514 12257 2 1017.561563 509.7876 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 5.97 2477.8 - 4.90E+06 - - - 0.8186 - 1.265 0.221 - 145.1 1 1 0 0.0008 9 0 0 0 - - - - - 1.3531 0.9897 221125_WJC_METTL3_EV_vs_WT_F03.12260.12260.2 0.000265 26-Dec L.AIPSAAAAAAAAGR[166.11].L "sp|P26599|PTBP1_HUMAN,tr|A0A0U1RRM4|A0A0U1RRM4_HUMAN,tr|A6NLN1|A6NLN1_HUMAN,tr|A0A087WU68|A0A087WU68_HUMAN,tr|A0A7I2V621|A0A7I2V621_HUMAN,tr|A0A087WTS6|A0A087WTS6_HUMAN,tr|K7EK45|K7EK45_HUMAN" 7 1177.6443 1.21 28517 12260 2 1177.644898 589.8294 Polypyrimidine tract-binding protein 1 OS=Homo sapiens OX=9606 GN=PTBP1 PE=1 SV=1 9.79 2478 - 1.14E+06 - - - 0.5163 - 2.179 0.463 - 436.3 1 1 0 0.0006 14 0 0 0 6.55E+07 5.40E+07 - - - 4.4151 0.9629 221125_WJC_METTL3_EV_vs_WT_F03.12261.12261.2 0.925 24-Sep R.LASVPGSQTVVVK.E sp|O00592|PODXL_HUMAN 1 1283.7449 1.31 28518 12261 2 1283.74703 642.8797 Podocalyxin OS=Homo sapiens OX=9606 GN=PODXL PE=1 SV=2 8.75 2478.1 - 2.21E+06 - - - 1.6577 - 1.288 0.063 - 185.1 1 2 0 0.0021 13 0 0 0 1.77E+07 1.35E+07 - - - 0.1552 0.9999 221125_WJC_METTL3_EV_vs_WT_F03.12262.12262.2 1.70E-07 22-Oct K.VVYGDTDSVMC[160.03]R[166.11].F "sp|P28340|DPOD1_HUMAN,tr|M0QZR8|M0QZR8_HUMAN,tr|A0A2R8Y705|A0A2R8Y705_HUMAN,tr|M0QXE6|M0QXE6_HUMAN,tr|M0R2B7|M0R2B7_HUMAN,tr|A0A087WYJ2|A0A087WYJ2_HUMAN" 6 1410.6147 0.15 28519 12262 2 1410.614522 706.3146 DNA polymerase delta catalytic subunit OS=Homo sapiens OX=9606 GN=POLD1 PE=1 SV=2 4.21 2478.2 - 351461 - - - -0.1304 - 2.207 0.621 - 344 1 2 0 -0.0002 12 0 0 0 5.28E+05 3.48E+06 - - - 5.7106 0.9933 221125_WJC_METTL3_EV_vs_WT_F03.12266.12266.3 1.43E-05 13/36 L.HLLDPDVVAR[166.11].F sp|Q86U44|MTA70_HUMAN 1 1143.6276 0.001 28521 12266 3 1143.625588 382.2165 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 5.21 2478.7 - 641500 - - - -1.7392 - 2.323 0.457 - 447.8 1 1 0 -0.002 10 0 0 0 0.00E+00 1.60E+07 - - - 6.0961 0.9982 221125_WJC_METTL3_EV_vs_WT_F03.12267.12267.2 0.55 14-Aug R.NAASFPLR.S "sp|Q6KC79|NIPBL_HUMAN,tr|A0A590UJS4|A0A590UJS4_HUMAN" 2 874.4661 0.95 28522 12267 2 874.464789 438.2403 Nipped-B-like protein OS=Homo sapiens OX=9606 GN=NIPBL PE=1 SV=2 9.75 2478.8 - 1.69E+06 - - - -1.5003 - 1.612 0.241 - 308.4 1 2 0 -0.0013 8 0 0 0 5.85E+07 6.15E+07 - - - 2.2607 0.9917 221125_WJC_METTL3_EV_vs_WT_F03.12269.12269.2 0.00743 20-Sep K.VLTPEEQLADK[136.11].L sp|O75822|EIF3J_HUMAN 1 1249.6645 1.59 28524 12269 2 1249.668982 625.8395 Eukaryotic translation initiation factor 3 subunit J OS=Homo sapiens OX=9606 GN=EIF3J PE=1 SV=2 4.14 2479 - 918500 - - - 3.5602 - 1.43 0.297 - 90 1 2 0 0.0044 11 0 0 0 6.48E+07 4.08E+07 - - - 2.2008 0.9881 221125_WJC_METTL3_EV_vs_WT_F03.12273.12273.2 0.000234 18-Oct L.SFETTEESLR[166.11].N "sp|P22626|ROA2_HUMAN,tr|A0A7I2YQN4|A0A7I2YQN4_HUMAN,tr|A0A7I2V4N0|A0A7I2V4N0_HUMAN,tr|A0A7I2V4N1|A0A7I2V4N1_HUMAN,tr|A0A7I2V4I6|A0A7I2V4I6_HUMAN,tr|A0A087WUI2|A0A087WUI2_HUMAN,tr|A0A7I2V4S4|A0A7I2V4S4_HUMAN,tr|A0A7I2V323|A0A7I2V323_HUMAN,tr|A0A7I2V3P1|A0A7I2V3P1_HUMAN,tr|A0A7I2V3P7|A0A7I2V3P7_HUMAN" 10 1207.5596 1.3 28526 12273 2 1207.558106 604.7871 Heterogeneous nuclear ribonucleoproteins A2\B1 OS=Homo sapiens OX=9606 GN=HNRNPA2B1 PE=1 SV=2 4.25 2479.5 - 4.90E+06 - - - -1.2513 - 2.049 0.47 - 301.5 1 1 0 -0.0015 10 0 0 0 1.15E+08 8.85E+07 - - - 4.5143 0.9934 221125_WJC_METTL3_EV_vs_WT_F03.12276.12276.2 0.199 12-May K.LNWSAPR[166.11].D "sp|O75794|CD123_HUMAN,tr|X6RKY7|X6RKY7_HUMAN,tr|X6RA30|X6RA30_HUMAN" 3 852.4482 1.38 28529 12276 2 852.447748 427.2314 Cell division cycle protein 123 homolog OS=Homo sapiens OX=9606 GN=CDC123 PE=1 SV=1 9.75 2479.7 - 850499 - - - -0.4786 - 1.268 0.152 - 75.3 1 2 0 -0.0004 7 0 0 0 1.75E+07 1.27E+07 - - - 0.9159 0.9998 221125_WJC_METTL3_EV_vs_WT_F03.12278.12278.2 3.38E-06 22-Nov R.LIPGSNLDSEPR[166.11].L "sp|Q6P4E1|GOLM2_HUMAN,tr|A0A3B3IRW9|A0A3B3IRW9_HUMAN,tr|H0YM51|H0YM51_HUMAN" 3 1306.6756 1.51 28531 12278 2 1306.673787 654.3451 Protein GOLM2 OS=Homo sapiens OX=9606 GN=GOLM2 PE=1 SV=2 4.37 2480 - 321175 - - - -1.4258 - 2.139 0.503 - 519.6 1 2 0 -0.0019 12 0 0 0 4.66E+07 3.08E+07 - - - 4.7562 0.9999 221125_WJC_METTL3_EV_vs_WT_F03.12281.12281.2 4.42E-05 20-Nov K.EAALSTALSEK.R "sp|P02545|LMNA_HUMAN,tr|A0A6Q8PF80|A0A6Q8PF80_HUMAN,tr|A0A804HL68|A0A804HL68_HUMAN,tr|Q5TCI8|Q5TCI8_HUMAN,tr|A0A6Q8PFJ0|A0A6Q8PFJ0_HUMAN,tr|A0A6Q8PHQ9|A0A6Q8PHQ9_HUMAN,tr|A0A6Q8PGH0|A0A6Q8PGH0_HUMAN,tr|Q3BDU5|Q3BDU5_HUMAN" 8 1118.5819 3.93 28532 12281 2 1118.581859 560.2982 Prelamin-A\C OS=Homo sapiens OX=9606 GN=LMNA PE=1 SV=1 4.53 2480.4 - 4.70E+06 - - - -0.0536 - 2.33 0.463 - 402.3 1 2 0 -0.0001 11 0 0 0 8.60E+07 2.19E+07 - - - 4.749 0.9661 221125_WJC_METTL3_EV_vs_WT_F03.12282.12282.2 0.00387 18-Sep K.FYSVYGSGQR[166.11].A "sp|Q9Y3D9|RT23_HUMAN,tr|J3QLR8|J3QLR8_HUMAN" 2 1172.549 2.1 28533 12282 2 1172.540532 587.2818 "28S ribosomal protein S23, mitochondrial OS=Homo sapiens OX=9606 GN=MRPS23 PE=1 SV=2" 8.59 2480.5 - 3.14E+06 - - - -7.2159 - 1.731 0.362 - 314.2 1 2 0 -0.0085 10 0 0 0 9.25E+07 4.40E+07 - - - 3.2437 0.9999 221125_WJC_METTL3_EV_vs_WT_F03.12283.12283.2 1.64E-05 18-Oct K.FYSVYGSGQR.A "sp|Q9Y3D9|RT23_HUMAN,tr|J3QLR8|J3QLR8_HUMAN" 2 1162.5407 2.13 28534 12283 2 1162.540191 582.2776 "28S ribosomal protein S23, mitochondrial OS=Homo sapiens OX=9606 GN=MRPS23 PE=1 SV=2" 8.59 2480.5 - 5.46E+06 - - - -0.4576 - 1.945 0.563 - 383.8 1 2 0 -0.0005 10 0 0 0 9.40E+07 4.40E+07 - - - 5.0561 1 221125_WJC_METTL3_EV_vs_WT_F03.12285.12285.3 3.06E-06 17/52 K.LLVPAAEGEDSLK[136.11]K[136.11].M "sp|Q96PU8|QKI_HUMAN,tr|F5GYM3|F5GYM3_HUMAN,tr|F5GXS8|F5GXS8_HUMAN,tr|H0YG47|H0YG47_HUMAN,tr|H0YGD6|H0YGD6_HUMAN" 5 1484.8421 2.24 28536 12285 3 1484.84051 495.9546 Protein quaking OS=Homo sapiens OX=9606 GN=QKI PE=1 SV=1 4.68 2480.6 - 2.47E+06 - - - -1.0776 - 2.626 0.533 - 389.4 1 2 0 -0.0016 14 0 0 0 8.54E+08 3.82E+08 - - - 7.0477 0.9896 221125_WJC_METTL3_EV_vs_WT_F03.12289.12289.2 0.494 14-Jun R.NLDITGVK.T "sp|Q9NWH9|SLTM_HUMAN,tr|H0YMR6|H0YMR6_HUMAN,tr|H0YLW7|H0YLW7_HUMAN,tr|H0YNF3|H0YNF3_HUMAN,tr|H0YMW8|H0YMW8_HUMAN,tr|H7BXE3|H7BXE3_HUMAN,tr|H0YLE6|H0YLE6_HUMAN,tr|H0YL55|H0YL55_HUMAN" 8 858.4811 1.37 28540 12289 2 858.48338 430.2478 SAFB-like transcription modulator OS=Homo sapiens OX=9606 GN=SLTM PE=1 SV=2 5.84 2481.1 - 698201 - - - 2.6757 - 1.387 0.23 - 92.3 3 2 0 0.0023 8 0 0 0 2.55E+07 1.86E+07 - - - 1.5126 0.9996 221125_WJC_METTL3_EV_vs_WT_F03.12292.12292.2 3.92E-05 14-Aug R.MQNSDFLR.E "sp|Q9NWS0|PIHD1_HUMAN,tr|M0QYF4|M0QYF4_HUMAN,tr|M0QZZ1|M0QZZ1_HUMAN,tr|M0QXD5|M0QXD5_HUMAN,tr|M0R3A4|M0R3A4_HUMAN,tr|M0R028|M0R028_HUMAN,tr|M0QZ61|M0QZ61_HUMAN,tr|M0R2P8|M0R2P8_HUMAN,tr|M0QZM3|M0QZM3_HUMAN,tr|M0QYA2|M0QYA2_HUMAN" 10 1009.4651 1.34 28541 12292 2 1009.464521 505.7398 PIH1 domain-containing protein 1 OS=Homo sapiens OX=9606 GN=PIH1D1 PE=1 SV=1 5.59 2481.5 - 1.15E+07 - - - -0.5884 - 1.753 0.339 - 257.8 1 2 0 -0.0006 8 0 0 0 2.54E+08 1.89E+08 - - - 3.2376 0.9811 221125_WJC_METTL3_EV_vs_WT_F03.12293.12293.2 0.00179 26-Oct L.AIPSAAAAAAAAGR.L "sp|P26599|PTBP1_HUMAN,tr|A0A0U1RRM4|A0A0U1RRM4_HUMAN,tr|A6NLN1|A6NLN1_HUMAN,tr|A0A087WU68|A0A087WU68_HUMAN,tr|A0A7I2V621|A0A7I2V621_HUMAN,tr|A0A087WTS6|A0A087WTS6_HUMAN,tr|K7EK45|K7EK45_HUMAN" 7 1167.636 1.21 28542 12293 2 1167.634463 584.8253 Polypyrimidine tract-binding protein 1 OS=Homo sapiens OX=9606 GN=PTBP1 PE=1 SV=1 9.79 2481.6 - 3.20E+06 - - - -1.3335 - 2.231 0.387 - 307 1 1 0 -0.0016 14 0 0 0 6.55E+07 5.40E+07 - - - 3.9126 0.9998 221125_WJC_METTL3_EV_vs_WT_F03.12295.12295.2 0.000438 22-Dec R.SLAASSSFYGQR[166.11].N "sp|Q13724|MOGS_HUMAN,tr|A0A3B3IRK6|A0A3B3IRK6_HUMAN,tr|A0A3B3IRW2|A0A3B3IRW2_HUMAN" 3 1282.6181 0.51 28544 12295 2 1282.619727 642.3163 Mannosyl-oligosaccharide glucosidase OS=Homo sapiens OX=9606 GN=MOGS PE=1 SV=5 8.46 2481.8 - 1.10E+06 - - - 1.2412 - 2.605 0.451 - 479.5 1 2 0 0.0016 12 0 0 0 1.15E+07 2.25E+07 - - - 4.8908 0.8895 221125_WJC_METTL3_EV_vs_WT_F03.12296.12296.2 2.04 16-Aug K.TVSDLIDQK[136.11].V "sp|Q9Y262|EIF3L_HUMAN,tr|B0QY89|B0QY89_HUMAN,tr|C9K0Q7|C9K0Q7_HUMAN,tr|H7C3A0|H7C3A0_HUMAN,tr|C9JHP4|C9JHP4_HUMAN" 5 1025.5484 0.45 28545 12296 2 1025.545146 513.7815 Eukaryotic translation initiation factor 3 subunit L OS=Homo sapiens OX=9606 GN=EIF3L PE=1 SV=1 4.21 2481.9 - 1.01E+06 - - - -3.2119 - 1.292 0.038 - 159.2 1 2 0 -0.0033 9 0 0 0 1.40E+07 3.14E+07 - - - 0.0618 0.9998 221125_WJC_METTL3_EV_vs_WT_F03.12298.12298.3 0.000287 13/36 K.LLELDPEHQR.A sp|P13674|P4HA1_HUMAN 1 1248.6463 1.89 28547 12298 3 1248.643784 417.2227 Prolyl 4-hydroxylase subunit alpha-1 OS=Homo sapiens OX=9606 GN=P4HA1 PE=1 SV=2 4.65 2482.2 - 627648 - - - -1.9749 - 2.323 0.372 - 358.2 1 2 0 -0.0025 10 0 0 0 3.25E+07 1.72E+07 - - - 5.1483 0.8412 221125_WJC_METTL3_EV_vs_WT_F03.12299.12299.2 0.905 12-Apr R.EYNWNVK[136.11].N "sp|Q8N7H5|PAF1_HUMAN,tr|B4DGJ5|B4DGJ5_HUMAN" 2 959.4592 0.82 28548 12299 2 959.456066 480.7369 RNA polymerase II-associated factor 1 homolog OS=Homo sapiens OX=9606 GN=PAF1 PE=1 SV=2 6.1 2482.3 - 622125 - - - -3.2987 - 0.934 0.192 - 60.1 8 2 0 -0.0032 7 0 0 0 5.85E+06 7.17E+06 - - - -0.1616 1 221125_WJC_METTL3_EV_vs_WT_F03.12303.12303.3 1.18E-05 Dec-44 R.ALEEANADLEVK.L "sp|P02533|K1C14_HUMAN,sp|P08779|K1C16_HUMAN,sp|P19012|K1C15_HUMAN,sp|P13646|K1C13_HUMAN,tr|K7EMD9|K7EMD9_HUMAN,tr|K7ERE3|K7ERE3_HUMAN" 6 1300.6511 83.27 28550 12303 3 1300.650059 434.5576 "Keratin, type I cytoskeletal 14 OS=Homo sapiens OX=9606 GN=KRT14 PE=1 SV=4" 4 2482.9 - 1.03E+07 - - - -0.7704 - 2.27 0.494 - 244.5 1 2 0 -0.001 12 0 0 0 2.84E+08 3.42E+06 - - - 6.3196 0.9995 221125_WJC_METTL3_EV_vs_WT_F03.12304.12304.2 0.00195 14-Aug K.GFVVINQK[136.11].G "sp|Q92526|TCPW_HUMAN,sp|P40227|TCPZ_HUMAN" 2 911.532 0.44 28551 12304 2 911.53032 456.7733 T-complex protein 1 subunit zeta-2 OS=Homo sapiens OX=9606 GN=CCT6B PE=1 SV=5 8.75 2482.9 - 4.41E+06 - - - -1.8452 - 1.707 0.434 - 287.5 1 2 0 -0.0017 8 0 0 0 2.08E+08 4.72E+08 - - - 3.8587 0.9999 221125_WJC_METTL3_EV_vs_WT_F03.12305.12305.2 1.73E-06 13/24 R.LGGSPFGPAGTGK[136.11].T "sp|Q14204|DYHC1_HUMAN,tr|A0A7P0T8N2|A0A7P0T8N2_HUMAN,tr|A0A7P0T9C4|A0A7P0T9C4_HUMAN,tr|A0A7P0TBJ7|A0A7P0TBJ7_HUMAN,tr|A0A804HHY6|A0A804HHY6_HUMAN,tr|A0A7P0T9K2|A0A7P0T9K2_HUMAN,tr|A0A7P0TB64|A0A7P0TB64_HUMAN,tr|A0A2R8Y706|A0A2R8Y706_HUMAN,tr|A0A7P0T916|A0A7P0T916_HUMAN,tr|A0A7P0TB75|A0A7P0TB75_HUMAN,tr|A0A7P0T8W5|A0A7P0T8W5_HUMAN,tr|A0A7P0T9S3|A0A7P0T9S3_HUMAN,tr|A0A7P0TAF3|A0A7P0TAF3_HUMAN,tr|A0A7P0T9F1|A0A7P0T9F1_HUMAN,tr|A0A7P0TAW9|A0A7P0TAW9_HUMAN,tr|A0A2R8YGC7|A0A2R8YGC7_HUMAN,tr|A0A7P0TA13|A0A7P0TA13_HUMAN,tr|A0A7P0T934|A0A7P0T934_HUMAN,tr|A0A7P0TAV5|A0A7P0TAV5_HUMAN,tr|A0A7P0T7V5|A0A7P0T7V5_HUMAN,tr|A0A7P0T9R4|A0A7P0T9R4_HUMAN,tr|A0A2R8Y5T0|A0A2R8Y5T0_HUMAN,tr|A0A7P0T990|A0A7P0T990_HUMAN,tr|A0A7P0T942|A0A7P0T942_HUMAN,tr|A0A2R8YFZ7|A0A2R8YFZ7_HUMAN,tr|A0A7P0T825|A0A7P0T825_HUMAN,tr|A0A2R8Y6H2|A0A2R8Y6H2_HUMAN,tr|A0A7P0TAM4|A0A7P0TAM4_HUMAN" 28 1152.6019 1.75 28552 12305 2 1152.601745 577.3082 Cytoplasmic dynein 1 heavy chain 1 OS=Homo sapiens OX=9606 GN=DYNC1H1 PE=1 SV=5 8.75 2483 - 1.88E+06 - - - -0.1111 - 2.641 0.485 - 402.3 1 2 0 -0.0001 13 0 0 0 5.94E+07 3.40E+07 - - - 5.1157 0.9669 221125_WJC_METTL3_EV_vs_WT_F03.12306.12306.2 0.00809 24-Nov R.LGGSPFGPAGTGK.T "sp|Q14204|DYHC1_HUMAN,tr|A0A7P0T8N2|A0A7P0T8N2_HUMAN,tr|A0A7P0T9C4|A0A7P0T9C4_HUMAN,tr|A0A7P0TBJ7|A0A7P0TBJ7_HUMAN,tr|A0A804HHY6|A0A804HHY6_HUMAN,tr|A0A7P0T9K2|A0A7P0T9K2_HUMAN,tr|A0A7P0TB64|A0A7P0TB64_HUMAN,tr|A0A2R8Y706|A0A2R8Y706_HUMAN,tr|A0A7P0T916|A0A7P0T916_HUMAN,tr|A0A7P0TB75|A0A7P0TB75_HUMAN,tr|A0A7P0T8W5|A0A7P0T8W5_HUMAN,tr|A0A7P0T9S3|A0A7P0T9S3_HUMAN,tr|A0A7P0TAF3|A0A7P0TAF3_HUMAN,tr|A0A7P0T9F1|A0A7P0T9F1_HUMAN,tr|A0A7P0TAW9|A0A7P0TAW9_HUMAN,tr|A0A2R8YGC7|A0A2R8YGC7_HUMAN,tr|A0A7P0TA13|A0A7P0TA13_HUMAN,tr|A0A7P0T934|A0A7P0T934_HUMAN,tr|A0A7P0TAV5|A0A7P0TAV5_HUMAN,tr|A0A7P0T7V5|A0A7P0T7V5_HUMAN,tr|A0A7P0T9R4|A0A7P0T9R4_HUMAN,tr|A0A2R8Y5T0|A0A2R8Y5T0_HUMAN,tr|A0A7P0T990|A0A7P0T990_HUMAN,tr|A0A7P0T942|A0A7P0T942_HUMAN,tr|A0A2R8YFZ7|A0A2R8YFZ7_HUMAN,tr|A0A7P0T825|A0A7P0T825_HUMAN,tr|A0A2R8Y6H2|A0A2R8Y6H2_HUMAN,tr|A0A7P0TAM4|A0A7P0TAM4_HUMAN" 28 1144.5877 1.99 28553 12306 2 1144.583671 573.3011 Cytoplasmic dynein 1 heavy chain 1 OS=Homo sapiens OX=9606 GN=DYNC1H1 PE=1 SV=5 8.75 2483.1 - 1.82E+06 - - - -3.4965 - 1.622 0.106 - 243.5 1 2 0 -0.004 13 0 0 0 6.79E+07 3.41E+07 - - - 1.064 0.9998 221125_WJC_METTL3_EV_vs_WT_F03.12311.12311.3 0.00081 Aug-32 R.YVHTFFGC[160.03]K.E "sp|Q6ZRP7|QSOX2_HUMAN,tr|H0Y430|H0Y430_HUMAN" 2 1157.5328 1.05 28558 12311 3 1157.532244 386.8515 Sulfhydryl oxidase 2 OS=Homo sapiens OX=9606 GN=QSOX2 PE=1 SV=3 8.21 2483.7 - 810960 - - - -0.4812 - 1.728 0.396 - 88 1 2 0 -0.0006 9 0 0 0 1.10E+07 1.04E+07 - - - 4.6033 0.9984 221125_WJC_METTL3_EV_vs_WT_F03.12312.12312.3 0.0236 13/36 R.LQEVFGHAIK[136.11].A "sp|P54136|SYRC_HUMAN,tr|E5RJM9|E5RJM9_HUMAN,tr|E5RH09|E5RH09_HUMAN" 3 1148.6433 1.24 28559 12312 3 1148.640549 383.8884 "Arginine--tRNA ligase, cytoplasmic OS=Homo sapiens OX=9606 GN=RARS1 PE=1 SV=2" 6.75 2483.8 - 565195 - - - -2.4333 - 1.744 0.311 - 150.8 1 2 0 -0.0028 10 0 0 0 4.45E+07 3.59E+07 - - - 3.6309 0.9995 221125_WJC_METTL3_EV_vs_WT_F03.12314.12314.2 0.000735 16-Sep R.QFSSSYLSR.S sp|P35527|K1C9_HUMAN 1 1073.5142 4396.76 28560 12314 2 1073.513803 537.7644 "Keratin, type I cytoskeletal 9 OS=Homo sapiens OX=9606 GN=KRT9 PE=1 SV=3" 8.75 2484 - 5.51E+07 - - - -0.3456 - 1.875 0.306 - 343.7 1 2 0 -0.0004 9 0 0 0 3.04E+09 6.91E+05 - - - 3.1196 0.9991 221125_WJC_METTL3_EV_vs_WT_F03.12315.12315.2 0.0011 16-Aug R.VEFMDDTSR[166.11].S sp|P62857|RS28_HUMAN 1 1108.4734 1.02 28561 12315 2 1108.472294 555.244 40S ribosomal protein S28 OS=Homo sapiens OX=9606 GN=RPS28 PE=1 SV=1 4.03 2484.1 - 1.86E+07 - - - -1.0375 - 1.725 0.268 - 265.3 1 2 0 -0.0011 9 0 0 0 6.45E+08 6.35E+08 - - - 2.5975 1 221125_WJC_METTL3_EV_vs_WT_F03.12316.12316.3 5.31E-09 19/52 K.LLVPAAEGEDSLKK.M "sp|Q96PU8|QKI_HUMAN,tr|F5GYM3|F5GYM3_HUMAN,tr|F5GXS8|F5GXS8_HUMAN,tr|H0YG47|H0YG47_HUMAN,tr|H0YGD6|H0YGD6_HUMAN" 5 1468.8137 2.24 28562 12316 3 1468.811679 490.6118 Protein quaking OS=Homo sapiens OX=9606 GN=QKI PE=1 SV=1 4.68 2484.1 - 2.14E+07 - - - -1.3827 - 2.815 0.614 - 489.4 1 2 0 -0.002 14 0 0 0 8.57E+08 3.83E+08 - - - 8.1354 0.9997 221125_WJC_METTL3_EV_vs_WT_F03.12317.12317.2 0.000499 20-Nov K.VLTPEEQLADK.L sp|O75822|EIF3J_HUMAN 1 1241.6503 1.6 28563 12317 2 1241.649341 621.8324 Eukaryotic translation initiation factor 3 subunit J OS=Homo sapiens OX=9606 GN=EIF3J PE=1 SV=2 4.14 2484.2 - 2.38E+06 - - - -0.7989 - 1.912 0.423 - 472.1 1 2 0 -0.001 11 0 0 0 6.53E+07 4.08E+07 - - - 3.9184 0.9999 221125_WJC_METTL3_EV_vs_WT_F03.12323.12323.2 5.52E-06 18-Nov K.AAYDIEVNTR.R "sp|O75955|FLOT1_HUMAN,tr|A2AB10|A2AB10_HUMAN,tr|A2ABJ5|A2ABJ5_HUMAN,tr|A2AB09|A2AB09_HUMAN,tr|A0A140T9C3|A0A140T9C3_HUMAN,tr|A0A140T9R1|A0A140T9R1_HUMAN,tr|A0A140T959|A0A140T959_HUMAN,tr|A0A140T905|A0A140T905_HUMAN,tr|A2AB12|A2AB12_HUMAN,tr|A0A140T9X0|A0A140T9X0_HUMAN" 10 1150.5619 3.26 28567 12323 2 1150.56262 576.2882 Flotillin-1 OS=Homo sapiens OX=9606 GN=FLOT1 PE=1 SV=3 4.37 2484.9 - 1.22E+06 - - - 0.6675 - 2.067 0.54 - 437.4 1 2 0 0.0008 10 0 0 0 2.35E+07 7.21E+06 - - - 5.056 0.9992 221125_WJC_METTL3_EV_vs_WT_F03.12325.12325.2 0.00223 16-Sep K.TFITQQGIK[136.11].S "sp|Q96CW1|AP2M1_HUMAN,tr|A0A087WY71|A0A087WY71_HUMAN,tr|C9JJ47|C9JJ47_HUMAN,tr|C9JTK4|C9JTK4_HUMAN,tr|C9JGT8|C9JGT8_HUMAN,tr|E9PFW3|E9PFW3_HUMAN" 6 1042.5902 0.52 28569 12325 2 1042.591341 522.3024 AP-2 complex subunit mu OS=Homo sapiens OX=9606 GN=AP2M1 PE=1 SV=2 8.41 2485.2 - 1.52E+06 - - - 1.0503 - 1.744 0.299 - 196.3 1 2 0 0.0011 9 0 0 0 2.03E+07 3.88E+07 - - - 2.8581 0.9985 221125_WJC_METTL3_EV_vs_WT_F03.12326.12326.2 0.00768 14-Aug K.QVFQSLPK[136.11].S "sp|Q96DA6|TIM14_HUMAN,tr|A0A2R8Y817|A0A2R8Y817_HUMAN,tr|F2Z3A7|F2Z3A7_HUMAN,tr|G5E9V2|G5E9V2_HUMAN" 4 953.5426 0.96 28570 12326 2 953.541135 477.7786 Mitochondrial import inner membrane translocase subunit TIM14 OS=Homo sapiens OX=9606 GN=DNAJC19 PE=1 SV=3 8.75 2485.3 - 1.28E+06 - - - -1.5018 - 1.395 0.317 - 244.6 1 2 0 -0.0014 8 0 0 0 5.41E+07 5.62E+07 - - - 2.3859 0.9979 221125_WJC_METTL3_EV_vs_WT_F03.12327.12327.2 0.00127 26-Aug K.LLVPAAEGEDSLK[136.11]K[136.11].M "sp|Q96PU8|QKI_HUMAN,tr|F5GYM3|F5GYM3_HUMAN,tr|F5GXS8|F5GXS8_HUMAN,tr|H0YG47|H0YG47_HUMAN,tr|H0YGD6|H0YGD6_HUMAN" 5 1484.8421 2.58 28571 12327 2 1484.838785 743.4283 Protein quaking OS=Homo sapiens OX=9606 GN=QKI PE=1 SV=1 4.68 2485.4 - 860030 - - - -2.2393 - 1.688 0.295 - 113.4 1 2 0 -0.0033 14 0 0 0 4.02E+07 1.56E+07 - - - 2.5326 0.9998 221125_WJC_METTL3_EV_vs_WT_F03.12329.12329.2 0.00132 20-Sep R.GLLGDAPNDPR.G "sp|P33240|CSTF2_HUMAN,sp|Q9H0L4|CSTFT_HUMAN,tr|E9PID8|E9PID8_HUMAN,tr|E7EWR4|E7EWR4_HUMAN" 4 1123.5622 3.06 28572 12329 2 1123.5617 562.7884 Cleavage stimulation factor subunit 2 OS=Homo sapiens OX=9606 GN=CSTF2 PE=1 SV=1 4.21 2485.6 - 1.12E+07 - - - -0.4326 - 1.916 0.442 - 203.5 1 2 0 -0.0005 11 0 0 0 3.07E+08 1.00E+08 - - - 4.0645 0.9997 221125_WJC_METTL3_EV_vs_WT_F03.12333.12333.2 0.000287 16-Aug R.GDLC[160.03]ALAER.L "sp|Q6QNY0|BL1S3_HUMAN,tr|K7EN58|K7EN58_HUMAN" 2 1003.4757 1.97 28575 12333 2 1003.474792 502.7451 Biogenesis of lysosome-related organelles complex 1 subunit 3 OS=Homo sapiens OX=9606 GN=BLOC1S3 PE=1 SV=1 4.37 2486 - 1.84E+06 - - - -0.8849 - 1.845 0.371 - 189.4 1 2 0 -0.0009 9 0 0 0 5.16E+07 2.62E+07 - - - 3.5529 0.998 221125_WJC_METTL3_EV_vs_WT_F03.12335.12335.3 0.000721 15/36 R.LQEVFGHAIK.A "sp|P54136|SYRC_HUMAN,tr|E5RJM9|E5RJM9_HUMAN,tr|E5RH09|E5RH09_HUMAN" 3 1140.6291 1.13 28577 12335 3 1140.627533 381.217 "Arginine--tRNA ligase, cytoplasmic OS=Homo sapiens OX=9606 GN=RARS1 PE=1 SV=2" 6.75 2486.2 - 1.76E+06 - - - -1.4124 - 2.199 0.192 - 227.4 1 2 0 -0.0016 10 0 0 0 4.04E+07 3.57E+07 - - - 2.9815 0.9998 221125_WJC_METTL3_EV_vs_WT_F03.12339.12339.2 2.39E-08 13/24 R.AVAGDASESALLK.C sp|P05023|AT1A1_HUMAN 1 1230.6456 1.68 28579 12339 2 1230.647586 616.3301 Sodium\potassium-transporting ATPase subunit alpha-1 OS=Homo sapiens OX=9606 GN=ATP1A1 PE=1 SV=1 4.37 2486.7 - 3.27E+06 - - - 1.6284 - 2.518 0.535 - 357.9 1 2 0 0.002 13 0 0 0 7.68E+07 4.57E+07 - - - 5.362 0.9983 221125_WJC_METTL3_EV_vs_WT_F03.12343.12343.2 0.038 14-Sep K.IYQYVINK[136.11].E "sp|P17812|PYRG1_HUMAN,tr|A0A3B3ITH9|A0A3B3ITH9_HUMAN,tr|A0A3B3ITF6|A0A3B3ITF6_HUMAN,tr|A0A3B3IRQ8|A0A3B3IRQ8_HUMAN,tr|A0A3B3ITB8|A0A3B3ITB8_HUMAN,tr|A0A3B3IRI2|A0A3B3IRI2_HUMAN" 6 1047.5844 0.84 28583 12343 2 1047.585432 524.7995 CTP synthase 1 OS=Homo sapiens OX=9606 GN=CTPS1 PE=1 SV=2 8.5 2487.2 - 822777 - - - 0.9546 - 1.456 0.265 - 211.9 1 2 0 0.001 8 0 0 0 3.04E+07 3.60E+07 - - - 2.131 0.9963 221125_WJC_METTL3_EV_vs_WT_F03.12344.12344.2 0.00501 16-Sep R.LTIQANLNR[166.11].L sp|Q9UKN8|TF3C4_HUMAN 1 1051.6014 3 28584 12344 2 1051.605423 526.808 General transcription factor 3C polypeptide 4 OS=Homo sapiens OX=9606 GN=GTF3C4 PE=1 SV=2 9.75 2487.3 - 508845 - - - 3.8608 - 1.991 0.291 - 220 1 2 0 0.0041 9 0 0 0 2.90E+07 9.69E+06 - - - 3.1813 0.9997 221125_WJC_METTL3_EV_vs_WT_F03.12350.12350.2 0.000196 13/26 K.LLVPAAEGEDSLKK.M "sp|Q96PU8|QKI_HUMAN,tr|F5GYM3|F5GYM3_HUMAN,tr|F5GXS8|F5GXS8_HUMAN,tr|H0YG47|H0YG47_HUMAN,tr|H0YGD6|H0YGD6_HUMAN" 5 1468.8137 2.58 28588 12350 2 1468.810285 735.4141 Protein quaking OS=Homo sapiens OX=9606 GN=QKI PE=1 SV=1 4.68 2488 - 2.61E+06 - - - -2.3318 - 2.308 0.561 - 392.1 1 2 0 -0.0034 14 0 0 0 4.02E+07 1.56E+07 - - - 5.2823 0.9996 221125_WJC_METTL3_EV_vs_WT_F03.12352.12352.2 0.00547 16-Aug K.GLVLGPIHK.N "sp|P08195|4F2_HUMAN,tr|A0A7P0TAN7|A0A7P0TAN7_HUMAN,tr|J3KPF3|J3KPF3_HUMAN,tr|F5H0E2|F5H0E2_HUMAN,tr|F5H056|F5H056_HUMAN,tr|H0YH36|H0YH36_HUMAN,tr|A0A7P0TAT7|A0A7P0TAT7_HUMAN,tr|F5GZI0|F5GZI0_HUMAN,tr|H0YFS2|H0YFS2_HUMAN,tr|A0A7P0T8U7|A0A7P0T8U7_HUMAN,tr|A0A7P0T9F7|A0A7P0T9F7_HUMAN,tr|A0A7P0TBF8|A0A7P0TBF8_HUMAN,tr|A0A7P0T8F1|A0A7P0T8F1_HUMAN,tr|A0A7P0Z4A0|A0A7P0Z4A0_HUMAN,tr|F5GZS6|F5GZS6_HUMAN,tr|A0A7P0Z4P5|A0A7P0Z4P5_HUMAN,tr|A0A7P0TAS6|A0A7P0TAS6_HUMAN" 17 932.5807 1.1 28590 12352 2 932.579761 467.2976 4F2 cell-surface antigen heavy chain OS=Homo sapiens OX=9606 GN=SLC3A2 PE=1 SV=3 8.76 2488.3 - 1.41E+06 - - - -1.0466 - 1.789 0.366 - 257.2 1 2 0 -0.001 9 0 0 0 2.17E+07 1.98E+07 - - - 3.4267 0.9998 221125_WJC_METTL3_EV_vs_WT_F03.12355.12355.2 0.00122 18-Sep K.GEFTIETEGK.T "sp|P41250|GARS_HUMAN,tr|H7C443|H7C443_HUMAN,tr|A0A6Q8PGI6|A0A6Q8PGI6_HUMAN,tr|A0A6Q8PGA8|A0A6Q8PGA8_HUMAN,tr|A0A6Q8PGW4|A0A6Q8PGW4_HUMAN,tr|A0A6Q8PGZ8|A0A6Q8PGZ8_HUMAN,tr|A0A6Q8PHH9|A0A6Q8PHH9_HUMAN,tr|A0A6Q8PHI7|A0A6Q8PHI7_HUMAN" 8 1109.5241 1.03 28591 12355 2 1109.523829 555.7693 Glycine--tRNA ligase OS=Homo sapiens OX=9606 GN=GARS1 PE=1 SV=3 4.25 2488.6 - 2.30E+06 - - - -0.2172 - 1.736 0.48 - 243.8 1 2 0 -0.0002 10 0 0 0 4.01E+07 3.91E+07 - - - 4.1258 0.9993 221125_WJC_METTL3_EV_vs_WT_F03.12356.12356.2 0.00129 16-Jul R.EYLDYDDTR.Y "sp|Q9BVI4|NOC4L_HUMAN,tr|F5H303|F5H303_HUMAN" 2 1188.4935 0.96 28592 12356 2 1188.496912 595.254 Nucleolar complex protein 4 homolog OS=Homo sapiens OX=9606 GN=NOC4L PE=1 SV=1 3.84 2488.8 - 529691 - - - 2.8725 - 1.62 0.517 - 215.5 1 2 0 0.0034 9 0 0 0 1.86E+07 1.93E+07 - - - 4.2542 0.9757 221125_WJC_METTL3_EV_vs_WT_F03.12358.12358.3 0.621 Aug-44 K.NLGVVVAPHTLK.L sp|Q9BYD2|RM09_HUMAN 1 1246.7398 1.8 28594 12358 3 1246.739054 416.5872 "39S ribosomal protein L9, mitochondrial OS=Homo sapiens OX=9606 GN=MRPL9 PE=1 SV=2" 8.76 2489 - 1.11E+06 - - - -0.5639 - 1.56 0.164 - 67.6 5 2 0 -0.0007 12 0 0 0 1.66E+07 9.22E+06 - - - 1.2773 0.9909 221125_WJC_METTL3_EV_vs_WT_F03.12363.12363.2 0.00561 16-Jul K.AINTLNGLR.L "sp|Q12926|ELAV2_HUMAN,sp|P26378|ELAV4_HUMAN,sp|Q15717|ELAV1_HUMAN,tr|A0A494C0Q5|A0A494C0Q5_HUMAN,tr|A0A494C0M6|A0A494C0M6_HUMAN,tr|B1AM48|B1AM48_HUMAN,tr|A0A494C0F8|A0A494C0F8_HUMAN,tr|M0QZR9|M0QZR9_HUMAN,tr|A0A494C147|A0A494C147_HUMAN,tr|A0A494C015|A0A494C015_HUMAN,tr|A0A494C1D9|A0A494C1D9_HUMAN,tr|A0A0R4J2E6|A0A0R4J2E6_HUMAN,tr|A0A494C173|A0A494C173_HUMAN,tr|A0A0A0MRX1|A0A0A0MRX1_HUMAN,tr|A0A494C011|A0A494C011_HUMAN,tr|B1APY9|B1APY9_HUMAN" 16 970.556 39.36 28597 12363 2 970.560121 486.2853 ELAV-like protein 2 OS=Homo sapiens OX=9606 GN=ELAVL2 PE=1 SV=2 9.79 2489.6 - 2.48E+06 - - - 4.2677 - 1.558 0.306 - 102 1 2 0 0.0041 9 0 0 0 7.54E+07 1.91E+06 - - - 2.5826 0.9993 221125_WJC_METTL3_EV_vs_WT_F03.12370.12370.2 0.578 16-Oct K.VETFSGVYK[136.11].K "sp|P62081|RS7_HUMAN,tr|A0A2R8Y623|A0A2R8Y623_HUMAN" 2 1036.5321 0.91 28602 12370 2 1036.531457 519.2733 40S ribosomal protein S7 OS=Homo sapiens OX=9606 GN=RPS7 PE=1 SV=1 5.97 2490.4 - 1.14E+07 - - - -0.5837 - 1.862 0.255 - 328.2 1 2 0 -0.0006 9 0 0 0 5.77E+08 6.32E+08 - - - 2.7227 0.9998 221125_WJC_METTL3_EV_vs_WT_F03.12375.12375.2 2.26E-05 13/22 K.LLQAQGVEVPSK[136.11].D "sp|O60841|IF2P_HUMAN,tr|A0A087WUT6|A0A087WUT6_HUMAN" 2 1275.7278 0.85 28607 12375 2 1275.729066 638.8712 Eukaryotic translation initiation factor 5B OS=Homo sapiens OX=9606 GN=EIF5B PE=1 SV=4 6 2490.8 - 926721 - - - 0.9908 - 2.391 0.428 - 567.6 1 2 0 0.0013 12 0 0 0 1.97E+07 2.33E+07 - - - 4.4954 0.9998 221125_WJC_METTL3_EV_vs_WT_F03.12376.12376.2 0.00606 15/22 K.TPLALAGSPTPK[136.11].N "sp|O95785|WIZ_HUMAN,tr|A0A669KBG4|A0A669KBG4_HUMAN,tr|A0A2R8YFV2|A0A2R8YFV2_HUMAN,tr|A0A669KAV7|A0A669KAV7_HUMAN,tr|M0QXA7|M0QXA7_HUMAN,tr|A0A669KBH9|A0A669KBH9_HUMAN,tr|B9EGQ5|B9EGQ5_HUMAN" 7 1159.6692 1.36 28608 12376 2 1159.66736 580.8419 Protein Wiz OS=Homo sapiens OX=9606 GN=WIZ PE=1 SV=2 8.41 2490.9 - 907402 - - - -1.6074 - 2.789 0.457 - 928.2 1 2 0 -0.0019 12 0 0 0 3.38E+07 2.50E+07 - - - 5.1146 0.9921 221125_WJC_METTL3_EV_vs_WT_F03.12377.12377.2 0.0744 16-Dec K.IRDILAQVK.Q sp|Q9NZI8|IF2B1_HUMAN 1 1054.6499 1.47 28609 12377 2 1054.648043 528.3322 Insulin-like growth factor 2 mRNA-binding protein 1 OS=Homo sapiens OX=9606 GN=IGF2BP1 PE=1 SV=2 8.75 2491 - 784675 - - - -1.7409 - 2.21 0.262 - 655.6 1 2 1 -0.0018 9 0 0 0 2.97E+07 2.01E+07 - - - 3.2697 0.9998 221125_WJC_METTL3_EV_vs_WT_F03.12378.12378.2 3.41E-07 22-Dec K.LLQAQGVEVPSK.D "sp|O60841|IF2P_HUMAN,tr|A0A087WUT6|A0A087WUT6_HUMAN" 2 1267.7136 0.85 28610 12378 2 1267.711578 634.8641 Eukaryotic translation initiation factor 5B OS=Homo sapiens OX=9606 GN=EIF5B PE=1 SV=4 6 2491.2 - 666342 - - - -1.5966 - 2.284 0.507 - 445.7 1 2 0 -0.002 12 0 0 0 1.97E+07 2.33E+07 - - - 4.9582 1 221125_WJC_METTL3_EV_vs_WT_F03.12379.12379.2 8.74E-06 13/26 K.VQALEEANNDLENK.L sp|P35527|K1C9_HUMAN 1 1585.7584 999 28611 12379 2 1585.761732 793.8865 "Keratin, type I cytoskeletal 9 OS=Homo sapiens OX=9606 GN=KRT9 PE=1 SV=3" 4 2491.3 - 242207 - - - 2.1138 - 2.715 0.578 - 495.2 1 2 0 0.0034 14 0 0 0 5.34E+06 0.00E+00 - - - 5.8155 0.9998 221125_WJC_METTL3_EV_vs_WT_F03.12383.12383.2 0.000753 14-Sep K.GFVVINQK.G "sp|Q92526|TCPW_HUMAN,sp|P40227|TCPZ_HUMAN" 2 903.5178 0.44 28613 12383 2 903.517727 452.7662 T-complex protein 1 subunit zeta-2 OS=Homo sapiens OX=9606 GN=CCT6B PE=1 SV=5 8.75 2491.7 - 9.74E+06 - - - -0.083 - 1.835 0.462 - 373.9 1 2 0 -0.0001 8 0 0 0 2.09E+08 4.74E+08 - - - 4.2841 0.9991 221125_WJC_METTL3_EV_vs_WT_F03.12384.12384.2 0.0203 16-Sep K.IALEDVPEK.Q sp|O43148|MCES_HUMAN 1 1012.5441 1.45 28614 12384 2 1012.546125 507.2793 mRNA cap guanine-N7 methyltransferase OS=Homo sapiens OX=9606 GN=RNMT PE=1 SV=1 4.14 2491.8 - 2.03E+06 - - - 2.0226 - 1.959 0.313 - 244.7 1 2 0 0.002 9 0 0 0 9.75E+07 6.73E+07 - - - 3.2976 0.9111 221125_WJC_METTL3_EV_vs_WT_F03.12385.12385.2 0.00105 14-Sep T.NEGIQYLR[166.11].D "sp|P46783|RS10_HUMAN,tr|A0A2R8Y6L3|A0A2R8Y6L3_HUMAN,tr|F6U211|F6U211_HUMAN,tr|A0A1W2PQS6|A0A1W2PQS6_HUMAN,tr|A0A2R8YFH6|A0A2R8YFH6_HUMAN,tr|A0A2R8Y7H1|A0A2R8Y7H1_HUMAN,tr|S4R435|S4R435_HUMAN" 7 1001.517 0.1 28615 12385 2 1001.516515 501.7658 40S ribosomal protein S10 OS=Homo sapiens OX=9606 GN=RPS10 PE=1 SV=1 6 2491.8 - 2.07E+06 - - - -0.4483 - 2.036 0.107 - 400 1 1 0 -0.0004 8 0 0 0 9.42E+07 9.84E+08 - - - 1.9755 1 221125_WJC_METTL3_EV_vs_WT_F03.12386.12386.2 6.22E-07 13/22 K.TPLALAGSPTPK.N "sp|O95785|WIZ_HUMAN,tr|A0A669KBG4|A0A669KBG4_HUMAN,tr|A0A2R8YFV2|A0A2R8YFV2_HUMAN,tr|A0A669KAV7|A0A669KAV7_HUMAN,tr|M0QXA7|M0QXA7_HUMAN,tr|A0A669KBH9|A0A669KBH9_HUMAN,tr|B9EGQ5|B9EGQ5_HUMAN" 7 1151.655 1.36 28616 12386 2 1151.657103 576.8348 Protein Wiz OS=Homo sapiens OX=9606 GN=WIZ PE=1 SV=2 8.41 2491.9 - 1.55E+06 - - - 1.8052 - 2.838 0.542 - 633.3 1 2 0 0.0021 12 0 0 0 3.41E+07 2.50E+07 - - - 5.7881 0.9988 221125_WJC_METTL3_EV_vs_WT_F03.12387.12387.2 0.00566 16-Aug K.FEPEYSQIK.Q "sp|Q6PKG0|LARP1_HUMAN,tr|A0A0B4J210|A0A0B4J210_HUMAN,tr|H0YC33|H0YC33_HUMAN,tr|E5RH50|E5RH50_HUMAN" 4 1139.5499 0.93 28617 12387 2 1139.548311 570.7822 La-related protein 1 OS=Homo sapiens OX=9606 GN=LARP1 PE=1 SV=2 4.53 2492 - 1.33E+06 - - - -1.3856 - 1.396 0.348 - 222.1 1 2 0 -0.0016 9 0 0 0 2.37E+07 2.56E+07 - - - 2.576 0.9932 221125_WJC_METTL3_EV_vs_WT_F03.12388.12388.2 0.2 16-Oct K.IR[166.11]DILAQVK[136.11].Q sp|Q9NZI8|IF2B1_HUMAN 1 1072.6723 1.47 28618 12388 2 1072.672999 537.3435 Insulin-like growth factor 2 mRNA-binding protein 1 OS=Homo sapiens OX=9606 GN=IGF2BP1 PE=1 SV=2 8.75 2492.1 - 1.25E+06 - - - 0.606 - 2.079 0.241 - 454 1 2 1 0.0006 9 0 0 0 2.97E+07 2.01E+07 - - - 2.9382 0.9982 221125_WJC_METTL3_EV_vs_WT_F03.12390.12390.2 0.000141 18-Aug R.YNVPNSAIYK[136.11].R "sp|Q86U86|PB1_HUMAN,tr|H0Y5B5|H0Y5B5_HUMAN,tr|E7EVG2|E7EVG2_HUMAN" 3 1175.6066 2.62 28620 12390 2 1175.601949 588.8106 Protein polybromo-1 OS=Homo sapiens OX=9606 GN=PBRM1 PE=1 SV=1 8.5 2492.3 - 667864 - - - -3.9767 - 1.665 0.49 - 174.8 1 2 0 -0.0047 10 0 0 0 5.49E+07 2.10E+07 - - - 4.0817 1 221125_WJC_METTL3_EV_vs_WT_F03.12391.12391.2 1.75E-07 13/26 K.VLQATVVAVGSGSK[136.11].G "sp|P61604|CH10_HUMAN,tr|S4R3N1|S4R3N1_HUMAN,tr|B8ZZL8|B8ZZL8_HUMAN" 3 1322.7649 1 28621 12391 2 1322.764808 662.3897 "10 kDa heat shock protein, mitochondrial OS=Homo sapiens OX=9606 GN=HSPE1 PE=1 SV=2" 8.72 2492.5 - 605694 - - - -0.0816 - 2.807 0.558 - 656.7 1 2 0 -0.0001 14 0 0 0 7.32E+07 7.32E+07 - - - 5.7524 0.8909 221125_WJC_METTL3_EV_vs_WT_F03.12392.12392.2 6.16 22-Jul K.LFTEVEGTC[160.03]TGK[136.11].Y "sp|P62487|RPB7_HUMAN,tr|E9PIU7|E9PIU7_HUMAN,tr|E9PKH3|E9PKH3_HUMAN,tr|H0YEE4|H0YEE4_HUMAN" 4 1348.6424 0.29 28622 12392 2 1348.640387 675.3285 DNA-directed RNA polymerase II subunit RPB7 OS=Homo sapiens OX=9606 GN=POLR2G PE=1 SV=1 4.53 2492.6 - 199639 - - - -1.5052 - 1.111 0.018 - 74.3 2 2 0 -0.002 12 0 0 0 6.36E+05 2.22E+06 - - - -0.6842 0.9988 221125_WJC_METTL3_EV_vs_WT_F03.12395.12395.3 0.0182 Sep-44 K.FVQLEGAHPLEK[136.11].S "sp|Q9BVI4|NOC4L_HUMAN,tr|F5H303|F5H303_HUMAN" 2 1374.7387 1.07 28623 12395 3 1374.739796 459.2535 Nucleolar complex protein 4 homolog OS=Homo sapiens OX=9606 GN=NOC4L PE=1 SV=1 5.4 2493 - 1.40E+06 - - - 0.7965 - 1.695 0.287 - 56.9 1 2 0 0.0011 12 0 0 0 2.10E+07 1.96E+07 - - - 3.2021 0.9998 221125_WJC_METTL3_EV_vs_WT_F03.12396.12396.2 0.000157 18-Oct R.YNVPNSAIYK.R "sp|Q86U86|PB1_HUMAN,tr|H0Y5B5|H0Y5B5_HUMAN,tr|E7EVG2|E7EVG2_HUMAN" 3 1167.5924 3.69 28624 12396 2 1167.591615 584.8035 Protein polybromo-1 OS=Homo sapiens OX=9606 GN=PBRM1 PE=1 SV=1 8.5 2493.1 - 1.31E+06 - - - -0.6929 - 1.792 0.473 - 306.3 1 2 0 -0.0008 10 0 0 0 7.97E+07 2.16E+07 - - - 4.1626 0.9999 221125_WJC_METTL3_EV_vs_WT_F03.12398.12398.2 0.000474 14/26 K.VLQATVVAVGSGSK.G "sp|P61604|CH10_HUMAN,tr|S4R3N1|S4R3N1_HUMAN,tr|B8ZZL8|B8ZZL8_HUMAN" 3 1314.7507 1 28626 12398 2 1314.751228 658.3826 "10 kDa heat shock protein, mitochondrial OS=Homo sapiens OX=9606 GN=HSPE1 PE=1 SV=2" 8.72 2493.3 - 1.02E+06 - - - 0.3894 - 2.741 0.498 - 754.9 1 2 0 0.0005 14 0 0 0 7.32E+07 7.32E+07 - - - 5.2494 0.9983 221125_WJC_METTL3_EV_vs_WT_F03.12400.12400.2 0.0408 18-Oct K.LENDQIESLR[166.11].Q "sp|P56192|SYMC_HUMAN,tr|H0YHL6|H0YHL6_HUMAN,tr|H0YI27|H0YI27_HUMAN,tr|H0YIP0|H0YIP0_HUMAN,tr|H0YI94|H0YI94_HUMAN" 5 1225.6178 0.87 28628 12400 2 1225.613503 613.8162 "Methionine--tRNA ligase, cytoplasmic OS=Homo sapiens OX=9606 GN=MARS1 PE=1 SV=2" 4.14 2493.5 - 763024 - - - -3.5068 - 2.18 0.34 - 279.1 1 2 0 -0.0043 10 0 0 0 8.17E+07 9.38E+07 - - - 3.7262 0.9994 221125_WJC_METTL3_EV_vs_WT_F03.12401.12401.2 0.0229 22-Oct K.FNPPTGTDTMVK.A "sp|P52948|NUP98_HUMAN,tr|A0A3B3ITD8|A0A3B3ITD8_HUMAN" 2 1306.6227 3.18 28629 12401 2 1306.621603 654.3186 Nuclear pore complex protein Nup98-Nup96 OS=Homo sapiens OX=9606 GN=NUP98 PE=1 SV=4 5.84 2493.6 - 1.46E+06 - - - -0.8687 - 1.642 0.361 - 255.2 1 2 0 -0.0011 12 0 0 0 3.09E+08 9.70E+07 - - - 3.0118 0.9042 221125_WJC_METTL3_EV_vs_WT_F03.12402.12402.3 0.000578 13/36 R.PNTLTLVHVR[166.11].L "sp|O75694|NU155_HUMAN,tr|E9PF10|E9PF10_HUMAN" 2 1158.6749 0.69 28630 12402 3 1158.677183 387.2322 Nuclear pore complex protein Nup155 OS=Homo sapiens OX=9606 GN=NUP155 PE=1 SV=1 10.18 2493.7 - 423924 - - - 2.0032 - 2.166 0.269 - 148.8 1 1 0 0.0023 10 0 0 0 2.57E+07 3.72E+07 - - - 3.7956 0.9999 221125_WJC_METTL3_EV_vs_WT_F03.12405.12405.2 6.57E-05 14/22 R.ALEEANADLEVK.L "sp|P02533|K1C14_HUMAN,sp|P08779|K1C16_HUMAN,sp|P19012|K1C15_HUMAN,sp|P13646|K1C13_HUMAN,tr|K7EMD9|K7EMD9_HUMAN,tr|K7ERE3|K7ERE3_HUMAN" 6 1300.6511 359.01 28632 12405 2 1300.651434 651.3328 "Keratin, type I cytoskeletal 14 OS=Homo sapiens OX=9606 GN=KRT14 PE=1 SV=4" 4 2494.1 - 6.43E+07 - - - 0.2868 - 2.85 0.467 - 595.5 1 2 0 0.0004 12 0 0 0 1.30E+10 3.63E+07 - - - 5.2458 0.9941 221125_WJC_METTL3_EV_vs_WT_F03.12407.12407.2 0.000981 20-Sep K.MESFSAVPPTK.E "sp|Q8IWZ3|ANKH1_HUMAN,tr|A0A0A0MQZ8|A0A0A0MQZ8_HUMAN,tr|H0Y472|H0Y472_HUMAN,tr|H0Y7Y3|H0Y7Y3_HUMAN,tr|H0Y4P6|H0Y4P6_HUMAN,tr|H7C0V5|H7C0V5_HUMAN,tr|H0Y785|H0Y785_HUMAN" 7 1192.5798 1.45 28633 12407 2 1192.578131 597.2972 Ankyrin repeat and KH domain-containing protein 1 OS=Homo sapiens OX=9606 GN=ANKHD1 PE=1 SV=1 5.75 2494.3 - 1.02E+06 - - - -1.4079 - 1.849 0.076 - 201.7 1 2 0 -0.0017 11 0 0 0 6.64E+07 4.57E+07 - - - 1.2646 0.9999 221125_WJC_METTL3_EV_vs_WT_F03.12408.12408.2 7.96E-06 18-Sep K.YDPTIEDSYR[166.11].E "sp|A6NIZ1|RP1BL_HUMAN,sp|P01111|RASN_HUMAN,sp|P01112|RASH_HUMAN,sp|P62834|RAP1A_HUMAN,sp|P61224|RAP1B_HUMAN,sp|P01116|RASK_HUMAN,tr|F5H7Y6|F5H7Y6_HUMAN,tr|A0A804HKM6|A0A804HKM6_HUMAN,tr|F5H500|F5H500_HUMAN,tr|E7ESV4|E7ESV4_HUMAN,tr|F5H491|F5H491_HUMAN,tr|F5GX62|F5GX62_HUMAN,tr|F5H4H0|F5H4H0_HUMAN,tr|F5H6R7|F5H6R7_HUMAN,tr|A0A075B6Q0|A0A075B6Q0_HUMAN,tr|F5H077|F5H077_HUMAN,tr|F5H004|F5H004_HUMAN,tr|A0A804HJ06|A0A804HJ06_HUMAN,tr|F5H0B7|F5H0B7_HUMAN,tr|F5GYB5|F5GYB5_HUMAN,tr|F5GWU8|F5GWU8_HUMAN,tr|F5GYH7|F5GYH7_HUMAN" 22 1267.5596 1 28634 12408 2 1267.559994 634.7871 Ras-related protein Rap-1b-like protein OS=Homo sapiens OX=9606 PE=2 SV=1 4.03 2494.4 - 803810 - - - 0.2974 - 1.763 0.609 - 368.8 1 2 0 0.0004 10 0 0 0 1.78E+07 1.78E+07 - - - 5.1217 0.8953 221125_WJC_METTL3_EV_vs_WT_F03.12409.12409.2 0.00623 14-Sep T.NEGIQYLR.D "sp|P46783|RS10_HUMAN,tr|A0A2R8Y6L3|A0A2R8Y6L3_HUMAN,tr|F6U211|F6U211_HUMAN,tr|A0A1W2PQS6|A0A1W2PQS6_HUMAN,tr|A0A2R8YFH6|A0A2R8YFH6_HUMAN,tr|A0A2R8Y7H1|A0A2R8Y7H1_HUMAN,tr|S4R435|S4R435_HUMAN" 7 991.5087 0.33 28635 12409 2 991.509248 496.7616 40S ribosomal protein S10 OS=Homo sapiens OX=9606 GN=RPS10 PE=1 SV=1 6 2494.4 - 3.49E+06 - - - 0.5587 - 2.004 0.103 - 372.2 1 1 0 0.0006 8 0 0 0 6.41E+07 1.95E+08 - - - 1.8981 0.9999 221125_WJC_METTL3_EV_vs_WT_F03.12410.12410.2 0.000117 18-Oct K.IISDNLTYC[160.03]K[136.11].C "sp|Q9Y2X3|NOP58_HUMAN,tr|H7BZ72|H7BZ72_HUMAN" 2 1233.6155 0.79 28636 12410 2 1233.615958 617.815 Nucleolar protein 58 OS=Homo sapiens OX=9606 GN=NOP58 PE=1 SV=1 5.83 2494.5 - 914384 - - - 0.3923 - 1.927 0.572 - 236.2 1 2 0 0.0005 10 0 0 0 1.17E+07 1.49E+07 - - - 5.0966 0.9999 221125_WJC_METTL3_EV_vs_WT_F03.12411.12411.2 6.10E-06 18-Sep K.YDPTIEDSYR.E "sp|A6NIZ1|RP1BL_HUMAN,sp|P01111|RASN_HUMAN,sp|P01112|RASH_HUMAN,sp|P62834|RAP1A_HUMAN,sp|P61224|RAP1B_HUMAN,sp|P01116|RASK_HUMAN,tr|F5H7Y6|F5H7Y6_HUMAN,tr|A0A804HKM6|A0A804HKM6_HUMAN,tr|F5H500|F5H500_HUMAN,tr|E7ESV4|E7ESV4_HUMAN,tr|F5H491|F5H491_HUMAN,tr|F5GX62|F5GX62_HUMAN,tr|F5H4H0|F5H4H0_HUMAN,tr|F5H6R7|F5H6R7_HUMAN,tr|A0A075B6Q0|A0A075B6Q0_HUMAN,tr|F5H077|F5H077_HUMAN,tr|F5H004|F5H004_HUMAN,tr|A0A804HJ06|A0A804HJ06_HUMAN,tr|F5H0B7|F5H0B7_HUMAN,tr|F5GYB5|F5GYB5_HUMAN,tr|F5GWU8|F5GWU8_HUMAN,tr|F5GYH7|F5GYH7_HUMAN" 22 1257.5513 1 28637 12411 2 1257.551777 629.7829 Ras-related protein Rap-1b-like protein OS=Homo sapiens OX=9606 PE=2 SV=1 4.03 2494.7 - 681004 - - - 0.3419 - 1.879 0.564 - 406 1 2 0 0.0004 10 0 0 0 1.78E+07 1.78E+07 - - - 4.9672 1 221125_WJC_METTL3_EV_vs_WT_F03.12413.12413.2 5.20E-08 15/24 R.TLATLSENNMEAK[136.11].F sp|Q9H2W6|RM46_HUMAN 1 1428.701 1.16 28639 12413 2 1428.704623 715.3578 "39S ribosomal protein L46, mitochondrial OS=Homo sapiens OX=9606 GN=MRPL46 PE=1 SV=1" 4.53 2494.9 - 359146 - - - 2.5394 - 2.5 0.634 - 384.1 1 2 0 0.0036 13 0 0 0 1.20E+07 1.03E+07 - - - 6.0743 0.9995 221125_WJC_METTL3_EV_vs_WT_F03.12415.12415.2 0.0572 22-Oct R.ALEEANTELEVK.L "sp|Q04695|K1C17_HUMAN,tr|K7EPJ9|K7EPJ9_HUMAN" 2 1344.6773 999 28641 12415 2 1344.67562 673.3459 "Keratin, type I cytoskeletal 17 OS=Homo sapiens OX=9606 GN=KRT17 PE=1 SV=2" 4.09 2495.2 - 315445 - - - -1.2315 - 2.267 0.293 - 251.5 1 2 0 -0.0017 12 0 0 0 4.78E+09 0.00E+00 - - - 3.3581 0.9997 221125_WJC_METTL3_EV_vs_WT_F03.12420.12420.2 0.000462 18-Oct K.SSLGPVGLDK.M "sp|P17987|TCPA_HUMAN,tr|F5H726|F5H726_HUMAN,tr|F5H136|F5H136_HUMAN,tr|F5GZI8|F5GZI8_HUMAN,tr|E7ERF2|E7ERF2_HUMAN,tr|F5H676|F5H676_HUMAN,tr|F5GYL4|F5GYL4_HUMAN" 7 971.5288 0.47 28644 12420 2 971.528246 486.7717 T-complex protein 1 subunit alpha OS=Homo sapiens OX=9606 GN=TCP1 PE=1 SV=1 5.55 2495.8 - 6.06E+06 - - - -0.5301 - 1.807 0.396 - 257.4 1 2 0 -0.0005 10 0 0 0 1.18E+09 2.51E+09 - - - 3.6172 0.9966 221125_WJC_METTL3_EV_vs_WT_F03.12421.12421.2 0.00263 18-Aug K.LENDQIESLR.Q "sp|P56192|SYMC_HUMAN,tr|H0YHL6|H0YHL6_HUMAN,tr|H0YI27|H0YI27_HUMAN,tr|H0YIP0|H0YIP0_HUMAN,tr|H0YI94|H0YI94_HUMAN" 5 1215.6095 0.82 28645 12421 2 1215.605307 608.812 "Methionine--tRNA ligase, cytoplasmic OS=Homo sapiens OX=9606 GN=MARS1 PE=1 SV=2" 4.14 2495.9 - 6.09E+06 - - - -3.4748 - 1.855 0.294 - 131.6 1 2 0 -0.0042 10 0 0 0 7.40E+07 9.05E+07 - - - 2.9359 1 221125_WJC_METTL3_EV_vs_WT_F03.12423.12423.2 2.05E-09 16/24 R.VSGVDGYETEGIR[166.11].G sp|Q14566|MCM6_HUMAN 1 1390.6604 0.9 28647 12423 2 1390.662489 696.3375 DNA replication licensing factor MCM6 OS=Homo sapiens OX=9606 GN=MCM6 PE=1 SV=1 4.14 2496.1 - 1.05E+06 - - - 1.5065 - 3.057 0.641 - 991.8 1 2 0 0.0021 13 0 0 0 1.45E+07 1.60E+07 - - - 6.6427 0.9999 221125_WJC_METTL3_EV_vs_WT_F03.12424.12424.2 4.20E-07 22-Nov K.VVVC[160.03]DNGTGFVK.C "sp|P61160|ARP2_HUMAN,tr|A0A1B0GWH0|A0A1B0GWH0_HUMAN,tr|A0A1B0GWD0|A0A1B0GWD0_HUMAN" 3 1293.6387 0 28648 12424 2 1293.639496 647.8266 Actin-related protein 2 OS=Homo sapiens OX=9606 GN=ACTR2 PE=1 SV=1 5.8 2496.2 - 979892 - - - 0.5983 - 2.135 0.548 - 325.2 1 2 0 0.0008 12 0 0 0 1.71E+07 6.84E+09 - - - 5.0839 0.9997 221125_WJC_METTL3_EV_vs_WT_F03.12426.12426.2 1.95E-06 24-Dec R.TLATLSENNMEAK.F sp|Q9H2W6|RM46_HUMAN 1 1420.6868 1.16 28650 12426 2 1420.68347 711.3507 "39S ribosomal protein L46, mitochondrial OS=Homo sapiens OX=9606 GN=MRPL46 PE=1 SV=1" 4.53 2496.4 - 482689 - - - -2.3404 - 2.413 0.536 - 305.5 1 2 0 -0.0033 13 0 0 0 1.20E+07 1.03E+07 - - - 5.2596 0.9998 221125_WJC_METTL3_EV_vs_WT_F03.12427.12427.2 8.79E-06 22-Oct K.AMAAPESGLEVR[166.11].D "sp|O14641|DVL2_HUMAN,tr|I3L0Z8|I3L0Z8_HUMAN,tr|I3L2N2|I3L2N2_HUMAN" 3 1239.6157 2.08 28651 12427 2 1239.616441 620.8151 Segment polarity protein dishevelled homolog DVL-2 OS=Homo sapiens OX=9606 GN=DVL2 PE=1 SV=1 4.53 2496.6 - 281643 - - - 0.6042 - 1.975 0.447 - 302.1 1 2 0 0.0007 12 0 0 0 4.56E+06 2.19E+06 - - - 4.133 0.9998 221125_WJC_METTL3_EV_vs_WT_F03.12430.12430.2 5.33E-05 18-Sep K.SSLGPVGLDK[136.11].M "sp|P17987|TCPA_HUMAN,tr|F5H726|F5H726_HUMAN,tr|F5H136|F5H136_HUMAN,tr|F5GZI8|F5GZI8_HUMAN,tr|E7ERF2|E7ERF2_HUMAN,tr|F5H676|F5H676_HUMAN,tr|F5GYL4|F5GYL4_HUMAN" 7 979.543 0.47 28652 12430 2 979.542853 490.7788 T-complex protein 1 subunit alpha OS=Homo sapiens OX=9606 GN=TCP1 PE=1 SV=1 5.55 2497 - 2.50E+07 - - - -0.1103 - 1.839 0.476 - 208.6 1 2 0 -0.0001 10 0 0 0 1.18E+09 2.51E+09 - - - 4.2572 1 221125_WJC_METTL3_EV_vs_WT_F03.12431.12431.2 4.65E-08 14/24 R.VSGVDGYETEGIR.G sp|Q14566|MCM6_HUMAN 1 1380.6521 0.9 28653 12431 2 1380.652125 691.3333 DNA replication licensing factor MCM6 OS=Homo sapiens OX=9606 GN=MCM6 PE=1 SV=1 4.14 2497.1 - 787587 - - - 0.0007 - 2.804 0.665 - 624 1 2 0 0 13 0 0 0 1.45E+07 1.60E+07 - - - 6.5989 0.9992 221125_WJC_METTL3_EV_vs_WT_F03.12432.12432.2 0.0409 18-Nov K.LAENIDAQLK[136.11].R "sp|P37198|NUP62_HUMAN,tr|M0QXN5|M0QXN5_HUMAN" 2 1121.6172 2.18 28654 12432 2 1121.620003 561.8159 Nuclear pore glycoprotein p62 OS=Homo sapiens OX=9606 GN=NUP62 PE=1 SV=3 4.37 2497.1 - 2.18E+06 - - - 2.5089 - 2.285 0.342 - 325.8 1 2 0 0.0028 10 0 0 0 1.28E+08 5.88E+07 - - - 3.8728 0.9999 221125_WJC_METTL3_EV_vs_WT_F03.12433.12433.2 3.22E-05 18-Nov R.AATSPALFNR[166.11].C "sp|Q14204|DYHC1_HUMAN,tr|A0A7P0T8N2|A0A7P0T8N2_HUMAN,tr|A0A7P0T9C4|A0A7P0T9C4_HUMAN,tr|A0A7P0TBJ7|A0A7P0TBJ7_HUMAN,tr|A0A7P0T9K2|A0A7P0T9K2_HUMAN,tr|A0A2R8Y706|A0A2R8Y706_HUMAN,tr|A0A7P0T916|A0A7P0T916_HUMAN,tr|A0A7P0TB75|A0A7P0TB75_HUMAN,tr|A0A7P0T8W5|A0A7P0T8W5_HUMAN,tr|A0A7P0TAF3|A0A7P0TAF3_HUMAN,tr|A0A7P0T9F1|A0A7P0T9F1_HUMAN,tr|A0A7P0TAW9|A0A7P0TAW9_HUMAN,tr|A0A7P0TA13|A0A7P0TA13_HUMAN,tr|A0A7P0T7V5|A0A7P0T7V5_HUMAN,tr|A0A7P0T9R4|A0A7P0T9R4_HUMAN,tr|A0A2R8Y5T0|A0A2R8Y5T0_HUMAN,tr|A0A2R8YFZ7|A0A2R8YFZ7_HUMAN,tr|A0A7P0T825|A0A7P0T825_HUMAN,tr|A0A2R8Y6H2|A0A2R8Y6H2_HUMAN,tr|A0A7P0TAM4|A0A7P0TAM4_HUMAN" 20 1056.5592 0.92 28655 12433 2 1056.559129 529.2869 Cytoplasmic dynein 1 heavy chain 1 OS=Homo sapiens OX=9606 GN=DYNC1H1 PE=1 SV=5 9.79 2497.2 - 1.74E+06 - - - -0.0322 - 2.384 0.487 - 532.9 1 2 0 0 10 0 0 0 2.56E+07 2.79E+07 - - - 5.063 0.9998 221125_WJC_METTL3_EV_vs_WT_F03.12435.12435.3 0.000163 15/52 K.VLQATVVAVGSGSK[136.11].G "sp|P61604|CH10_HUMAN,tr|S4R3N1|S4R3N1_HUMAN,tr|B8ZZL8|B8ZZL8_HUMAN" 3 1322.7649 0.84 28657 12435 3 1322.764675 441.9289 "10 kDa heat shock protein, mitochondrial OS=Homo sapiens OX=9606 GN=HSPE1 PE=1 SV=2" 8.72 2497.4 - 779290 - - - -0.1822 - 2.024 0.385 - 208.5 1 2 0 -0.0002 14 0 0 0 1.25E+07 1.49E+07 - - - 4.7061 0.9892 221125_WJC_METTL3_EV_vs_WT_F03.12436.12436.2 0.168 14-Aug R.SLVSDIGK[136.11].E sp|Q8WWH5|TRUB1_HUMAN 1 825.4687 1.09 28658 12436 2 825.467297 413.7416 Probable tRNA pseudouridine synthase 1 OS=Homo sapiens OX=9606 GN=TRUB1 PE=1 SV=1 5.55 2497.6 - 325298 - - - -1.7396 - 1.4 0.124 - 169.8 1 2 0 -0.0014 8 0 0 0 8.22E+06 7.56E+06 - - - 0.9712 0.9781 221125_WJC_METTL3_EV_vs_WT_F03.12437.12437.2 2.51E-05 26-Jul K.IIDSDEGPEC[160.03]HPPV.K sp|Q08554|DSC1_HUMAN 1 1563.6875 - 28659 12437 2 1563.689841 782.851 Desmocollin-1 OS=Homo sapiens OX=9606 GN=DSC1 PE=1 SV=2 3.91 2497.7 - 226248 - - - 1.4824 - 1.373 0.558 - 113.3 1 1 0 0.0023 14 0 0 0 - - - - - 3.9572 0.9998 221125_WJC_METTL3_EV_vs_WT_F03.12441.12441.2 5.16E-06 18-Sep K.VYTLSVSGDR[166.11].L "sp|O43684|BUB3_HUMAN,tr|J3QT28|J3QT28_HUMAN" 2 1105.5643 0.48 28661 12441 2 1105.564133 553.7894 Mitotic checkpoint protein BUB3 OS=Homo sapiens OX=9606 GN=BUB3 PE=1 SV=1 5.81 2498.1 - 1.68E+06 - - - -0.1583 - 2.038 0.38 - 312.5 1 2 0 -0.0002 10 0 0 0 5.40E+07 1.13E+08 - - - 3.8349 0.9983 221125_WJC_METTL3_EV_vs_WT_F03.12443.12443.2 0.173 16-Sep R.SLQQLAEER.S "sp|Q13813|SPTN1_HUMAN,tr|A0A0D9SF54|A0A0D9SF54_HUMAN,tr|A0A0D9SGF6|A0A0D9SGF6_HUMAN" 3 1072.5513 1.12 28663 12443 2 1072.551539 537.2829 "Spectrin alpha chain, non-erythrocytic 1 OS=Homo sapiens OX=9606 GN=SPTAN1 PE=1 SV=3" 4.53 2498.3 - 1.02E+06 - - - 0.235 - 1.717 0.182 - 248.3 1 2 0 0.0003 9 0 0 0 6.89E+07 6.16E+07 - - - 1.9491 0.9865 221125_WJC_METTL3_EV_vs_WT_F03.12445.12445.2 0.552 12-Jul K.VQLLPSR.R "sp|Q96HA1|P121A_HUMAN,sp|A6NF01|P121B_HUMAN,sp|A8CG34|P121C_HUMAN,tr|A0A6Q8PFH5|A0A6Q8PFH5_HUMAN" 4 811.4916 1.45 28665 12445 2 811.490998 406.7531 Nuclear envelope pore membrane protein POM 121 OS=Homo sapiens OX=9606 GN=POM121 PE=1 SV=2 9.72 2498.6 - 615114 - - - -0.7271 - 1.381 0.055 - 203.4 1 2 0 -0.0006 7 0 0 0 2.08E+07 1.44E+07 - - - 0.4699 0.989 221125_WJC_METTL3_EV_vs_WT_F03.12450.12450.2 0.271 12-Jul K.IQDWYDK.K sp|P35527|K1C9_HUMAN 1 966.4447 13.44 28668 12450 2 966.444113 484.2296 "Keratin, type I cytoskeletal 9 OS=Homo sapiens OX=9606 GN=KRT9 PE=1 SV=3" 4.21 2499.2 - 1.05E+06 - - - -0.6043 - 1.172 0.141 - 108.4 1 2 0 -0.0006 7 0 0 0 1.66E+07 1.24E+06 - - - 0.5851 0.9999 221125_WJC_METTL3_EV_vs_WT_F03.12452.12452.2 4.04E-05 18-Oct K.YAQNGQLFGR.F "sp|P42694|HELZ_HUMAN,tr|J3QS41|J3QS41_HUMAN,tr|A0A075B6R3|A0A075B6R3_HUMAN" 3 1152.5676 1.55 28670 12452 2 1152.566501 577.2911 Probable helicase with zinc finger domain OS=Homo sapiens OX=9606 GN=HELZ PE=1 SV=2 8.75 2499.3 - 1.39E+06 - - - -0.9587 - 1.999 0.569 - 335.1 1 2 0 -0.0011 10 0 0 0 3.86E+07 2.49E+07 - - - 5.1767 0.9972 221125_WJC_METTL3_EV_vs_WT_F03.12456.12456.3 0.05 Sep-44 R.ALEEANTELEVK.L "sp|Q04695|K1C17_HUMAN,tr|K7EPJ9|K7EPJ9_HUMAN" 2 1344.6773 139.1 28674 12456 3 1344.675954 449.233 "Keratin, type I cytoskeletal 17 OS=Homo sapiens OX=9606 GN=KRT17 PE=1 SV=2" 4.09 2499.7 - 553483 - - - -0.9831 - 1.654 0.239 - 109.4 1 2 0 -0.0013 12 0 0 0 7.97E+07 5.73E+05 - - - 2.599 0.9995 221125_WJC_METTL3_EV_vs_WT_F03.12458.12458.2 3.63E-05 22-Oct R.MLPQAATEDDIR.G sp|P98175|RBM10_HUMAN 1 1358.65 2.91 28676 12458 2 1358.646318 680.3323 RNA-binding protein 10 OS=Homo sapiens OX=9606 GN=RBM10 PE=1 SV=3 4.03 2500 - 336646 - - - -2.7211 - 1.989 0.522 - 315.7 1 2 0 -0.0037 12 0 0 0 1.41E+08 4.84E+07 - - - 4.7046 0.9992 221125_WJC_METTL3_EV_vs_WT_F03.12460.12460.2 0.867 16-Oct R.LAELQEQLK[136.11].A "sp|O60885|BRD4_HUMAN,sp|Q15059|BRD3_HUMAN,tr|M0QZD9|M0QZD9_HUMAN" 3 1078.6114 0.63 28677 12460 2 1078.610752 540.313 Bromodomain-containing protein 4 OS=Homo sapiens OX=9606 GN=BRD4 PE=1 SV=2 4.53 2500.2 - 2.05E+06 - - - -0.5776 - 2.187 0.179 - 314.6 1 2 0 -0.0006 9 0 0 0 1.94E+07 3.09E+07 - - - 2.6268 0.9988 221125_WJC_METTL3_EV_vs_WT_F03.12462.12462.2 0.00886 14-Jul R.NFIEGDYK.T "sp|Q9Y371|SHLB1_HUMAN,tr|A0A087WW40|A0A087WW40_HUMAN" 2 984.4553 1.2 28678 12462 2 984.454708 493.2349 Endophilin-B1 OS=Homo sapiens OX=9606 GN=SH3GLB1 PE=1 SV=1 4.37 2500.4 - 3.36E+06 - - - -0.5627 - 1.301 0.33 - 149.8 1 2 0 -0.0006 8 0 0 0 7.02E+07 5.83E+07 - - - 2.2718 0.8686 221125_WJC_METTL3_EV_vs_WT_F03.12463.12463.2 0.131 12-Sep R.LRVEFPR.S "sp|Q07955|SRSF1_HUMAN,sp|Q13242|SRSF9_HUMAN,tr|J3KTL2|J3KTL2_HUMAN,tr|S4R3G0|S4R3G0_HUMAN" 4 915.529 0.97 28679 12463 2 915.527315 458.7718 Serine\arginine-rich splicing factor 1 OS=Homo sapiens OX=9606 GN=SRSF1 PE=1 SV=2 9.6 2500.6 - 833144 - - - -1.8798 - 1.315 0.133 - 215.1 1 2 1 -0.0017 7 0 0 0 3.12E+07 3.21E+07 - - - 0.8905 0.9921 221125_WJC_METTL3_EV_vs_WT_F03.12464.12464.2 0.021 14-Jun R.NFIEGDYK[136.11].T "sp|Q9Y371|SHLB1_HUMAN,tr|A0A087WW40|A0A087WW40_HUMAN" 2 992.4695 1.2 28680 12464 2 992.468811 497.242 Endophilin-B1 OS=Homo sapiens OX=9606 GN=SH3GLB1 PE=1 SV=1 4.37 2500.6 - 2.67E+06 - - - -0.6559 - 1.258 0.148 - 157.9 1 2 0 -0.0007 8 0 0 0 7.01E+07 5.83E+07 - - - 0.8262 0.997 221125_WJC_METTL3_EV_vs_WT_F03.12468.12468.2 0.0171 18-Jul K.GMSVSDLADK.L "sp|Q16891|MIC60_HUMAN,tr|B9A067|B9A067_HUMAN,tr|C9J406|C9J406_HUMAN,tr|H7C463|H7C463_HUMAN" 4 1021.475 2.41 28682 12468 2 1021.476922 511.7448 MICOS complex subunit MIC60 OS=Homo sapiens OX=9606 GN=IMMT PE=1 SV=1 4.21 2501.1 - 2.93E+06 - - - 1.8708 - 1.464 0.268 - 97.6 1 2 0 0.0019 10 0 0 0 1.27E+08 5.28E+07 - - - 2.0838 0.9998 221125_WJC_METTL3_EV_vs_WT_F03.12470.12470.3 0.00467 Sep-36 R.KVLPLEEAYR.F sp|Q9H223|EHD4_HUMAN 1 1216.6816 0.66 28684 12470 3 1216.679609 406.5678 EH domain-containing protein 4 OS=Homo sapiens OX=9606 GN=EHD4 PE=1 SV=1 6.14 2501.3 - 1.00E+06 - - - -1.6142 - 1.848 0.394 - 140.1 1 2 0 -0.002 10 0 0 0 2.23E+07 3.36E+07 - - - 4.7256 0.9907 221125_WJC_METTL3_EV_vs_WT_F03.12471.12471.2 0.712 14-Jun K.LIQEIVDK[136.11].S "sp|Q06787|FMR1_HUMAN,tr|R9WNI0|R9WNI0_HUMAN,tr|A8MQB8|A8MQB8_HUMAN,tr|A0A087WXI3|A0A087WXI3_HUMAN,tr|G3V0J0|G3V0J0_HUMAN" 5 964.5684 3.17 28685 12471 2 964.568705 483.2915 Synaptic functional regulator FMR1 OS=Homo sapiens OX=9606 GN=FMR1 PE=1 SV=1 4.37 2501.4 - 1.00E+06 - - - 0.2675 - 1.354 0.128 - 64.7 3 2 0 0.0003 8 0 0 0 4.71E+07 1.49E+07 - - - 0.6872 0.9933 221125_WJC_METTL3_EV_vs_WT_F03.12473.12473.2 0.275 12-Aug R.K[136.11]IPIIIR[166.11].R "sp|P61218|RPAB2_HUMAN,tr|U3KQB0|U3KQB0_HUMAN,tr|U3KPY1|U3KPY1_HUMAN" 3 869.6181 1.27 28687 12473 2 869.616038 435.8163 "DNA-directed RNA polymerases I, II, and III subunit RPABC2 OS=Homo sapiens OX=9606 GN=POLR2F PE=1 SV=1" 11 2501.6 - 515458 - - - -2.4045 - 1.592 0.156 - 286 1 2 0 -0.0021 7 0 0 0 1.61E+07 1.27E+07 - - - 1.6659 0.9478 221125_WJC_METTL3_EV_vs_WT_F03.12482.12482.2 1.67 12-Jul K.LELAQYR[166.11].E sp|P25705|ATPA_HUMAN 1 901.4897 1.15 28692 12482 2 901.487679 451.7521 "ATP synthase subunit alpha, mitochondrial OS=Homo sapiens OX=9606 GN=ATP5F1A PE=1 SV=1" 6 2502.7 - 1.16E+06 - - - -2.2274 - 1.39 0.023 - 130.3 2 2 0 -0.002 7 0 0 0 2.64E+07 2.29E+07 - - - 0.1192 0.9929 221125_WJC_METTL3_EV_vs_WT_F03.12483.12483.2 0.388 18-Oct R.STIIGESISR.L sp|P54136|SYRC_HUMAN 1 1061.5717 0.52 28693 12483 2 1061.569128 531.7931 "Arginine--tRNA ligase, cytoplasmic OS=Homo sapiens OX=9606 GN=RARS1 PE=1 SV=2" 5.72 2502.9 - 724336 - - - -2.4115 - 1.652 0.161 - 274.3 1 2 0 -0.0026 10 0 0 0 1.24E+08 2.38E+08 - - - 1.6305 0.9951 221125_WJC_METTL3_EV_vs_WT_F03.12490.12490.3 0.116 Oct-44 R.IGDK[136.11]EGALTAFR[166.11].K "sp|Q15008|PSMD6_HUMAN,tr|C9J0E9|C9J0E9_HUMAN" 2 1294.7 0.26 28698 12490 3 1294.700167 432.574 26S proteasome non-ATPase regulatory subunit 6 OS=Homo sapiens OX=9606 GN=PSMD6 PE=1 SV=1 6.07 2503.6 - 918315 - - - 0.1128 - 1.788 0.291 - 100.4 2 2 1 0.0001 12 0 0 0 2.97E+06 1.14E+07 - - - 3.2557 0.9965 221125_WJC_METTL3_EV_vs_WT_F03.12491.12491.2 0.464 16-Aug K.LSDGVAVLK[136.11].V "sp|P10809|CH60_HUMAN,tr|A0A7I2V2X6|A0A7I2V2X6_HUMAN,tr|A0A7I2YQK6|A0A7I2YQK6_HUMAN,tr|A0A7I2V599|A0A7I2V599_HUMAN" 4 908.5422 1.36 28699 12491 2 908.542382 455.2784 "60 kDa heat shock protein, mitochondrial OS=Homo sapiens OX=9606 GN=HSPD1 PE=1 SV=2" 5.84 2503.7 - 903378 - - - 0.164 - 1.525 0.149 - 110.3 1 2 0 0.0001 9 0 0 0 4.62E+07 3.38E+07 - - - 1.3623 0.9998 221125_WJC_METTL3_EV_vs_WT_F03.12499.12499.2 2.52E-06 20-Sep R.DSLTGSSDLYK.R "sp|Q14671|PUM1_HUMAN,tr|Q5T1Z8|Q5T1Z8_HUMAN,tr|H0YDK8|H0YDK8_HUMAN,tr|Q5T1Z4|Q5T1Z4_HUMAN,tr|E9PR38|E9PR38_HUMAN" 5 1184.5561 0.94 28706 12499 2 1184.556097 593.2853 Pumilio homolog 1 OS=Homo sapiens OX=9606 GN=PUM1 PE=1 SV=3 4.21 2504.6 - 4.37E+06 - - - -0.0008 - 1.952 0.482 - 170.8 1 2 0 0 11 0 0 0 1.16E+08 1.23E+08 - - - 4.4105 0.9903 221125_WJC_METTL3_EV_vs_WT_F03.12500.12500.2 5.37 14-Sep R.LQIDVDGR[166.11].K sp|Q08J23|NSUN2_HUMAN 1 924.4904 1.29 28707 12500 2 924.489276 463.2525 RNA cytosine C(5)-methyltransferase NSUN2 OS=Homo sapiens OX=9606 GN=NSUN2 PE=1 SV=2 4.21 2504.6 - 3.20E+06 - - - -1.232 - 1.466 0.087 - 355.3 1 2 0 -0.0011 8 0 0 0 8.68E+07 6.75E+07 - - - 0.8369 0.9448 221125_WJC_METTL3_EV_vs_WT_F03.12501.12501.2 4.18 16-Jul R.EVLINNINR.R "sp|P05198|IF2A_HUMAN,tr|H0YJS4|H0YJS4_HUMAN,tr|G3V4T5|G3V4T5_HUMAN" 3 1083.6037 4.2 28708 12501 2 1083.601476 542.8091 Eukaryotic translation initiation factor 2 subunit 1 OS=Homo sapiens OX=9606 GN=EIF2S1 PE=1 SV=3 6.1 2504.7 - 2.30E+06 - - - -2.0127 - 1.207 0.054 - 136.6 1 2 0 -0.0022 9 0 0 0 5.39E+07 1.28E+07 - - - -0.0165 0.9991 221125_WJC_METTL3_EV_vs_WT_F03.12508.12508.2 0.0172 16-Aug K.NLEPALPGR.W "sp|Q15014|MO4L2_HUMAN,tr|Q5JXX2|Q5JXX2_HUMAN,tr|Q5JXX1|Q5JXX1_HUMAN,tr|Q5JXX6|Q5JXX6_HUMAN" 4 965.5294 0.9 28713 12508 2 965.529943 483.772 Mortality factor 4-like protein 2 OS=Homo sapiens OX=9606 GN=MORF4L2 PE=1 SV=1 6 2505.4 - 1.41E+06 - - - 0.5313 - 1.714 0.269 - 196 1 2 0 0.0005 9 0 0 0 5.83E+07 6.46E+07 - - - 2.5865 0.9565 221125_WJC_METTL3_EV_vs_WT_F03.12510.12510.2 4.22 12-Jun K.TLVFEQR.K "sp|Q9Y3A6|TMED5_HUMAN,tr|B1AKT3|B1AKT3_HUMAN,tr|M0R072|M0R072_HUMAN" 3 891.4814 1.13 28715 12510 2 891.480058 446.748 Transmembrane emp24 domain-containing protein 5 OS=Homo sapiens OX=9606 GN=TMED5 PE=1 SV=1 5.66 2505.7 - 893259 - - - -1.5244 - 1.215 0.038 - 144.8 1 2 0 -0.0014 7 0 0 0 2.59E+07 2.28E+07 - - - -0.0617 0.9993 221125_WJC_METTL3_EV_vs_WT_F03.12514.12514.2 0.0538 16-Sep K.LSDGVAVLK.V "sp|P10809|CH60_HUMAN,tr|A0A7I2V2X6|A0A7I2V2X6_HUMAN,tr|A0A7I2YQK6|A0A7I2YQK6_HUMAN,tr|A0A7I2V599|A0A7I2V599_HUMAN" 4 900.528 1.34 28717 12514 2 900.527683 451.2713 "60 kDa heat shock protein, mitochondrial OS=Homo sapiens OX=9606 GN=HSPD1 PE=1 SV=2" 5.84 2506.2 - 1.97E+06 - - - -0.3887 - 1.805 0.267 - 159.8 1 2 0 -0.0003 9 0 0 0 4.53E+07 3.38E+07 - - - 2.7215 0.9951 221125_WJC_METTL3_EV_vs_WT_F03.12516.12516.2 0.601 14-Jun K.ANFSLPEK.C "sp|Q1KMD3|HNRL2_HUMAN,tr|H3BQZ7|H3BQZ7_HUMAN" 2 904.4654 0.9 28719 12516 2 904.464439 453.24 Heterogeneous nuclear ribonucleoprotein U-like protein 2 OS=Homo sapiens OX=9606 GN=HNRNPUL2 PE=1 SV=1 6.05 2506.4 - 1.37E+06 - - - -1.0979 - 1.321 0.207 - 137.9 2 2 0 -0.001 8 0 0 0 1.48E+08 1.64E+08 - - - 1.2747 0.9997 221125_WJC_METTL3_EV_vs_WT_F03.12517.12517.2 1.88E-05 13/22 R.TLGYVDEAGTVK.L "sp|Q15477|SKIV2_HUMAN,tr|H7C4L3|H7C4L3_HUMAN" 2 1251.6347 1.1 28720 12517 2 1251.637563 626.8246 Helicase SKI2W OS=Homo sapiens OX=9606 GN=SKIV2L PE=1 SV=3 4.37 2506.5 - 1.09E+06 - - - 2.301 - 2.294 0.509 - 374.5 1 2 0 0.0029 12 0 0 0 2.34E+07 2.13E+07 - - - 4.9842 0.9966 221125_WJC_METTL3_EV_vs_WT_F03.12520.12520.2 0.0986 16-Sep R.SLYGLGGSK.R "sp|P48668|K2C6C_HUMAN,sp|P04259|K2C6B_HUMAN,sp|P02538|K2C6A_HUMAN" 3 880.4654 3.57 28721 12520 2 880.46508 441.24 "Keratin, type II cytoskeletal 6C OS=Homo sapiens OX=9606 GN=KRT6C PE=1 SV=3" 8.31 2506.9 - 572344 - - - -0.3998 - 1.371 0.196 - 242.3 1 2 0 -0.0004 9 0 0 0 2.52E+07 7.08E+06 - - - 1.4014 0.9908 221125_WJC_METTL3_EV_vs_WT_F03.12521.12521.2 0.000151 14/26 Y.LLAALGGNSSPSAK[136.11].D sp|P05387|RLA2_HUMAN 1 1292.718 1.34 28722 12521 2 1292.718751 647.3663 60S acidic ribosomal protein P2 OS=Homo sapiens OX=9606 GN=RPLP2 PE=1 SV=1 8.75 2507 - 808140 - - - 0.608 - 2.568 0.437 - 443.8 1 1 0 0.0008 14 0 0 0 1.80E+08 1.34E+08 - - - 4.6352 0.9987 221125_WJC_METTL3_EV_vs_WT_F03.12526.12526.2 0.0908 14-Aug R.SIYFSSPK[136.11].G "sp|P29372|3MG_HUMAN,tr|A2IDA3|A2IDA3_HUMAN" 2 935.4844 0.83 28725 12526 2 935.483756 468.7495 DNA-3-methyladenine glycosylase OS=Homo sapiens OX=9606 GN=MPG PE=1 SV=3 8.31 2507.6 - 1.52E+06 - - - -0.6702 - 1.453 0.279 - 212.4 1 2 0 -0.0006 8 0 0 0 3.21E+07 3.87E+07 - - - 2.2283 0.8146 221125_WJC_METTL3_EV_vs_WT_F03.12528.12528.2 0.124 20-Sep K.GVQLDSAGLER.L sp|Q5JTZ9|SYAM_HUMAN 1 1143.5884 1.38 28727 12528 2 1143.595859 572.8015 "Alanine--tRNA ligase, mitochondrial OS=Homo sapiens OX=9606 GN=AARS2 PE=1 SV=1" 4.37 2507.8 - 1.37E+06 - - - 6.5216 - 1.392 0.175 - 204.2 1 2 0 0.0075 11 0 0 0 2.43E+07 1.77E+07 - - - 1.2259 0.883 221125_WJC_METTL3_EV_vs_WT_F03.12530.12530.2 0.264 12-Sep R.LR[166.11]VEFPR[166.11].S "sp|Q07955|SRSF1_HUMAN,sp|Q13242|SRSF9_HUMAN,tr|J3KTL2|J3KTL2_HUMAN,tr|S4R3G0|S4R3G0_HUMAN" 4 935.5456 0.98 28729 12530 2 935.543781 468.7801 Serine\arginine-rich splicing factor 1 OS=Homo sapiens OX=9606 GN=SRSF1 PE=1 SV=2 9.6 2508 - 1.52E+06 - - - -1.9187 - 1.288 0.157 - 184.9 1 2 1 -0.0018 7 0 0 0 3.09E+07 3.16E+07 - - - 1.002 0.9604 221125_WJC_METTL3_EV_vs_WT_F03.12531.12531.2 0.00703 16-Oct G.TTIAGVVYK.D "sp|Q99436|PSB7_HUMAN,tr|Q5TBG5|Q5TBG5_HUMAN" 2 950.5437 0.67 28730 12531 2 950.542055 476.2791 Proteasome subunit beta type-7 OS=Homo sapiens OX=9606 GN=PSMB7 PE=1 SV=1 8.26 2508.2 - 914106 - - - -1.7127 - 1.726 0.362 - 359.3 1 1 0 -0.0016 9 0 0 0 2.96E+07 4.42E+07 - - - 3.2933 0.9897 221125_WJC_METTL3_EV_vs_WT_F03.12537.12537.2 0.00345 14/26 Y.LLAALGGNSSPSAK.D sp|P05387|RLA2_HUMAN 1 1284.7038 1.34 28734 12537 2 1284.7023 643.3592 60S acidic ribosomal protein P2 OS=Homo sapiens OX=9606 GN=RPLP2 PE=1 SV=1 8.75 2508.9 - 2.82E+06 - - - -1.1403 - 2.138 0.502 - 412 1 1 0 -0.0015 14 0 0 0 1.80E+08 1.34E+08 - - - 4.6552 0.9996 221125_WJC_METTL3_EV_vs_WT_F03.12538.12538.2 0.000276 20-Nov K.GC[160.03]GTVLLSGPR.K "sp|Q07020|RL18_HUMAN,tr|J3QQ67|J3QQ67_HUMAN,tr|F8VUA6|F8VUA6_HUMAN,tr|G3V203|G3V203_HUMAN,tr|H0YHA7|H0YHA7_HUMAN" 5 1115.5757 0.88 28735 12538 2 1115.573253 558.7951 60S ribosomal protein L18 OS=Homo sapiens OX=9606 GN=RPL18 PE=1 SV=2 8.25 2508.9 - 2.28E+06 - - - -2.2186 - 1.948 0.477 - 514.2 1 2 0 -0.0025 11 0 0 0 8.91E+07 1.02E+08 - - - 4.3672 0.9996 221125_WJC_METTL3_EV_vs_WT_F03.12539.12539.2 0.0124 14-Jun K.APIQWEER.N "sp|P50213|IDH3A_HUMAN,tr|H0YLI6|H0YLI6_HUMAN,tr|H0YM64|H0YM64_HUMAN,tr|H0YKD0|H0YKD0_HUMAN,tr|H0YL72|H0YL72_HUMAN,tr|H0YMU3|H0YMU3_HUMAN" 6 1027.5087 1.4 28736 12539 2 1027.508263 514.7616 "Isocitrate dehydrogenase [NAD] subunit alpha, mitochondrial OS=Homo sapiens OX=9606 GN=IDH3A PE=1 SV=1" 4.53 2509 - 1.92E+06 - - - -0.4195 - 1.504 0.406 - 166 1 2 0 -0.0004 8 0 0 0 6.50E+07 4.64E+07 - - - 3.2705 0.9921 221125_WJC_METTL3_EV_vs_WT_F03.12540.12540.2 0.378 18-Sep K.LNVTDSVINK.V sp|Q9BRS2|RIOK1_HUMAN 1 1101.603 0.92 28737 12540 2 1101.600542 551.8088 Serine\threonine-protein kinase RIO1 OS=Homo sapiens OX=9606 GN=RIOK1 PE=1 SV=2 5.84 2509.1 - 1.38E+06 - - - -2.2213 - 1.625 0.142 - 169.5 1 2 0 -0.0024 10 0 0 0 7.02E+07 7.63E+07 - - - 1.4442 0.9992 221125_WJC_METTL3_EV_vs_WT_F03.12541.12541.2 0.00117 16-Aug K.QLEDLSYC[160.03]R[166.11].E "sp|Q99567|NUP88_HUMAN,tr|I3L4K7|I3L4K7_HUMAN,tr|J3KMX1|J3KMX1_HUMAN" 3 1192.5422 5.54 28738 12541 2 1192.545139 597.2784 Nuclear pore complex protein Nup88 OS=Homo sapiens OX=9606 GN=NUP88 PE=1 SV=2 4.37 2509.2 - 1.35E+06 - - - 2.4704 - 1.813 0.414 - 202.9 1 2 0 0.0029 9 0 0 0 4.71E+07 8.50E+06 - - - 3.8192 0.9632 221125_WJC_METTL3_EV_vs_WT_F03.12542.12542.2 0.408 14-Sep K.TTDVLTIK.T sp|P82673|RT35_HUMAN 1 889.512 0.96 28739 12542 2 889.509675 445.7633 "28S ribosomal protein S35, mitochondrial OS=Homo sapiens OX=9606 GN=MRPS35 PE=1 SV=1" 5.5 2509.3 - 699572 - - - -2.6678 - 1.155 0.148 - 272.4 1 2 0 -0.0024 8 0 0 0 3.81E+07 3.96E+07 - - - 0.568 0.9749 221125_WJC_METTL3_EV_vs_WT_F03.12545.12545.2 0.0573 18-Sep L.NVELDPEIQK.V "sp|Q86Y46|K2C73_HUMAN,sp|Q7RTS7|K2C74_HUMAN,sp|Q3SY84|K2C71_HUMAN,sp|P04264|K2C1_HUMAN,tr|F8W1S1|F8W1S1_HUMAN" 5 1183.6085 1277.94 28740 12545 2 1183.607985 592.8115 "Keratin, type II cytoskeletal 73 OS=Homo sapiens OX=9606 GN=KRT73 PE=1 SV=1" 4.14 2509.7 - 5.08E+06 - - - -0.4081 - 1.859 0.328 - 237.6 1 1 0 -0.0005 10 0 0 0 2.04E+09 1.60E+06 - - - 3.1942 0.9995 221125_WJC_METTL3_EV_vs_WT_F03.12546.12546.2 0.00823 20-Nov K.LAQALLEQGGR.L sp|Q86XL3|ANKL2_HUMAN 1 1154.6408 2.23 28741 12546 2 1154.642503 578.3277 Ankyrin repeat and LEM domain-containing protein 2 OS=Homo sapiens OX=9606 GN=ANKLE2 PE=1 SV=4 6 2509.8 - 913070 - - - 1.5 - 2.494 0.288 - 439.2 1 2 0 0.0017 11 0 0 0 2.09E+07 9.40E+06 - - - 3.6399 0.9996 221125_WJC_METTL3_EV_vs_WT_F03.12548.12548.2 0.0362 16-Sep K.VNIISVTNK[136.11].G "sp|Q9BY44|EIF2A_HUMAN,tr|C9IZE1|C9IZE1_HUMAN,tr|H7C5Q3|H7C5Q3_HUMAN" 3 994.5902 0.03 28743 12548 2 994.589291 498.3024 Eukaryotic translation initiation factor 2A OS=Homo sapiens OX=9606 GN=EIF2A PE=1 SV=3 8.72 2510.1 - 1.10E+06 - - - -0.9602 - 1.911 0.358 - 306.1 1 2 0 -0.001 9 0 0 0 1.50E+06 4.78E+07 - - - 3.5585 0.9998 221125_WJC_METTL3_EV_vs_WT_F03.12549.12549.2 0.00059 22-Sep R.MLPQAATEDDIR[166.11].G sp|P98175|RBM10_HUMAN 1 1368.6583 2.98 28744 12549 2 1368.657529 685.3364 RNA-binding protein 10 OS=Homo sapiens OX=9606 GN=RBM10 PE=1 SV=3 4.03 2510.2 - 760153 - - - -0.5524 - 1.769 0.458 - 221.3 1 2 0 -0.0008 12 0 0 0 5.06E+07 1.70E+07 - - - 3.9244 0.9997 221125_WJC_METTL3_EV_vs_WT_F03.12551.12551.2 5.93E-08 20-Dec R.VLAETPDSFEK[136.11].H "sp|Q99567|NUP88_HUMAN,tr|J3KMX1|J3KMX1_HUMAN" 2 1242.6223 2.13 28746 12551 2 1242.619385 622.3184 Nuclear pore complex protein Nup88 OS=Homo sapiens OX=9606 GN=NUP88 PE=1 SV=2 4.14 2510.5 - 475521 - - - -2.3732 - 2.498 0.49 - 427 1 2 0 -0.0029 11 0 0 0 2.54E+08 1.19E+08 - - - 5.1358 0.9676 221125_WJC_METTL3_EV_vs_WT_F03.12556.12556.3 0.298 Jul-36 R.FIPLAR[166.11]PEVK[136.11].W "sp|Q9Y3Z3|SAMH1_HUMAN,tr|A0A2R8Y6J9|A0A2R8Y6J9_HUMAN,tr|A0A2R8YD90|A0A2R8YD90_HUMAN,tr|A0A2R8YCS7|A0A2R8YCS7_HUMAN,tr|A0A2R8YF51|A0A2R8YF51_HUMAN,tr|A0A2R8Y5D2|A0A2R8Y5D2_HUMAN" 6 1186.7193 0.45 28749 12556 3 1186.717989 396.5804 Deoxynucleoside triphosphate triphosphohydrolase SAMHD1 OS=Homo sapiens OX=9606 GN=SAMHD1 PE=1 SV=2 8.75 2511.1 - 778998 - - - -1.1039 - 1.425 0.16 - 51.4 3 2 0 -0.0013 10 0 0 0 9.58E+06 2.15E+07 - - - 1.137 0.9995 221125_WJC_METTL3_EV_vs_WT_F03.12557.12557.2 0.0049 14-Jul R.GLPFGC[160.03]SK.E "sp|P55795|HNRH2_HUMAN,sp|P31942|HNRH3_HUMAN,sp|P31943|HNRH1_HUMAN,tr|E5RGH4|E5RGH4_HUMAN,tr|D6RIH9|D6RIH9_HUMAN,tr|D6RJ04|D6RJ04_HUMAN,tr|E5RGV0|E5RGV0_HUMAN,tr|D6RFM3|D6RFM3_HUMAN,tr|E9PCY7|E9PCY7_HUMAN,tr|D6RIT2|D6RIT2_HUMAN,tr|D6R9T0|D6R9T0_HUMAN,tr|D6RIU0|D6RIU0_HUMAN,tr|H0YAQ2|H0YAQ2_HUMAN,tr|D6RAM1|D6RAM1_HUMAN,tr|D6RBM0|D6RBM0_HUMAN,tr|G8JLB6|G8JLB6_HUMAN,tr|D6RDU3|D6RDU3_HUMAN" 17 864.4164 0.99 28750 12557 2 864.416264 433.2155 Heterogeneous nuclear ribonucleoprotein H2 OS=Homo sapiens OX=9606 GN=HNRNPH2 PE=1 SV=1 8.22 2511.2 - 988404 - - - -0.1273 - 1.31 0.415 - 155.6 1 2 0 -0.0001 8 0 0 0 2.90E+08 2.94E+08 - - - 2.9205 0.9992 221125_WJC_METTL3_EV_vs_WT_F03.12558.12558.2 0.182 14-Aug K.TTDVLTIK[136.11].T sp|P82673|RT35_HUMAN 1 897.5262 0.96 28751 12558 2 897.525675 449.7704 "28S ribosomal protein S35, mitochondrial OS=Homo sapiens OX=9606 GN=MRPS35 PE=1 SV=1" 5.5 2511.4 - 1.47E+06 - - - -0.6384 - 1.747 0.256 - 229.5 1 2 0 -0.0006 8 0 0 0 3.81E+07 3.97E+07 - - - 2.6142 0.9998 221125_WJC_METTL3_EV_vs_WT_F03.12562.12562.2 6.79E-05 20-Sep K.LVMEEAPESYK.N sp|Q9Y3I0|RTCB_HUMAN 1 1294.6115 2.13 28753 12562 2 1294.610802 648.313 RNA-splicing ligase RtcB homolog OS=Homo sapiens OX=9606 GN=RTCB PE=1 SV=1 4.25 2511.9 - 6.02E+06 - - - -0.5422 - 1.613 0.505 - 279.7 1 2 0 -0.0007 11 0 0 0 1.26E+08 5.91E+07 - - - 4.0641 0.9997 221125_WJC_METTL3_EV_vs_WT_F03.12563.12563.2 0.00574 14-Aug K.SC[160.03]NC[160.03]LLLK[136.11].V "sp|P06733|ENOA_HUMAN,tr|A0A2R8Y6G6|A0A2R8Y6G6_HUMAN" 2 1014.5082 1.32 28754 12563 2 1014.507205 508.2614 Alpha-enolase OS=Homo sapiens OX=9606 GN=ENO1 PE=1 SV=2 7.79 2511.9 - 5.49E+06 - - - -0.9542 - 1.758 0.432 - 249.8 1 2 0 -0.001 8 0 0 0 3.94E+08 2.98E+08 - - - 3.933 0.9997 221125_WJC_METTL3_EV_vs_WT_F03.12564.12564.2 0.00305 18-Oct K.LNVTDSVINK[136.11].V sp|Q9BRS2|RIOK1_HUMAN 1 1109.6172 2.21 28755 12564 2 1109.615815 555.8159 Serine\threonine-protein kinase RIO1 OS=Homo sapiens OX=9606 GN=RIOK1 PE=1 SV=2 5.84 2512.1 - 1.43E+06 - - - -1.2383 - 2.251 0.367 - 304.9 1 2 0 -0.0014 10 0 0 0 8.87E+07 4.01E+07 - - - 4.016 0.9938 221125_WJC_METTL3_EV_vs_WT_F03.12566.12566.2 0.000117 13/24 F.AAPATATIATLQK.N "sp|A0AV96|RBM47_HUMAN,tr|B7Z8Z7|B7Z8Z7_HUMAN" 2 1255.7136 1.22 28757 12566 2 1255.713326 628.8641 RNA-binding protein 47 OS=Homo sapiens OX=9606 GN=RBM47 PE=1 SV=2 8.8 2512.3 - 825070 - - - -0.2198 - 2.462 0.514 - 633.5 1 1 0 -0.0003 13 0 0 0 1.53E+07 1.25E+07 - - - 5.1497 0.9996 221125_WJC_METTL3_EV_vs_WT_F03.12570.12570.2 0.0027 14-Oct K.MLEIDPQK.V "sp|P24752|THIL_HUMAN,tr|A0A5F9ZHD4|A0A5F9ZHD4_HUMAN,tr|A0A5F9ZHJ0|A0A5F9ZHJ0_HUMAN,tr|A0A5F9ZHL1|A0A5F9ZHL1_HUMAN,tr|A0A5F9ZI66|A0A5F9ZI66_HUMAN" 5 972.495 0.94 28759 12570 2 972.494148 487.2548 "Acetyl-CoA acetyltransferase, mitochondrial OS=Homo sapiens OX=9606 GN=ACAT1 PE=1 SV=1" 4.37 2512.8 - 6.54E+06 - - - -0.8946 - 1.539 0.404 - 397.2 1 2 0 -0.0009 8 0 0 0 1.90E+08 2.02E+08 - - - 3.3249 0.9998 221125_WJC_METTL3_EV_vs_WT_F03.12571.12571.2 0.00122 16-Oct R.NTDEMVELR[166.11].L "sp|P61978|HNRPK_HUMAN,tr|S4R457|S4R457_HUMAN,tr|Q5T6W2|Q5T6W2_HUMAN" 3 1115.5156 1.23 28760 12571 2 1115.514953 558.7651 Heterogeneous nuclear ribonucleoprotein K OS=Homo sapiens OX=9606 GN=HNRNPK PE=1 SV=1 4.14 2512.8 - 4.93E+06 - - - -0.6194 - 2.161 0.445 - 744 1 2 0 -0.0007 9 0 0 0 7.29E+08 5.95E+08 - - - 4.5569 0.9988 221125_WJC_METTL3_EV_vs_WT_F03.12572.12572.2 0.0495 18-Aug K.EVAQSLLNAK.E "sp|Q8NBT2|SPC24_HUMAN,tr|K7EJH0|K7EJH0_HUMAN,tr|K7EMX1|K7EMX1_HUMAN,tr|K7EJV2|K7EJV2_HUMAN,tr|K7ESQ2|K7ESQ2_HUMAN" 5 1071.5924 2.55 28761 12572 2 1071.592446 536.8035 Kinetochore protein Spc24 OS=Homo sapiens OX=9606 GN=SPC24 PE=1 SV=2 6.1 2512.9 - 1.69E+07 - - - 0.0205 - 1.589 0.259 - 213 1 2 0 0 10 0 0 0 5.66E+08 2.22E+08 - - - 2.2466 0.9998 221125_WJC_METTL3_EV_vs_WT_F03.12573.12573.2 0.0152 16-Nov R.NTDEMVELR.L "sp|P61978|HNRPK_HUMAN,tr|S4R457|S4R457_HUMAN,tr|Q5T6W2|Q5T6W2_HUMAN" 3 1105.5074 1.21 28762 12573 2 1105.50558 553.761 Heterogeneous nuclear ribonucleoprotein K OS=Homo sapiens OX=9606 GN=HNRNPK PE=1 SV=1 4.14 2512.9 - 5.32E+06 - - - -1.6228 - 2.297 0.446 - 877.8 1 2 0 -0.0018 9 0 0 0 7.19E+08 5.94E+08 - - - 4.7405 0.9988 221125_WJC_METTL3_EV_vs_WT_F03.12577.12577.2 0.025 16-Jul K.NGALSVLQK.S sp|Q10570|CPSF1_HUMAN 1 928.5342 0.55 28766 12577 2 928.535315 465.2744 Cleavage and polyadenylation specificity factor subunit 1 OS=Homo sapiens OX=9606 GN=CPSF1 PE=1 SV=2 8.75 2513.4 - 683430 - - - 1.2213 - 1.471 0.326 - 125.5 1 2 0 0.0011 9 0 0 0 9.24E+06 1.69E+07 - - - 2.565 0.9995 221125_WJC_METTL3_EV_vs_WT_F03.12581.12581.2 0.00612 14-Sep K.MLEIDPQK[136.11].V "sp|P24752|THIL_HUMAN,tr|A0A5F9ZHD4|A0A5F9ZHD4_HUMAN,tr|A0A5F9ZHJ0|A0A5F9ZHJ0_HUMAN,tr|A0A5F9ZHL1|A0A5F9ZHL1_HUMAN,tr|A0A5F9ZI66|A0A5F9ZI66_HUMAN" 5 980.5092 0.85 28768 12581 2 980.50794 491.2619 "Acetyl-CoA acetyltransferase, mitochondrial OS=Homo sapiens OX=9606 GN=ACAT1 PE=1 SV=1" 4.37 2513.9 - 4.91E+06 - - - -1.3034 - 1.602 0.405 - 309.8 1 2 0 -0.0013 8 0 0 0 1.91E+08 2.24E+08 - - - 3.4532 0.998 221125_WJC_METTL3_EV_vs_WT_F03.12582.12582.2 0.449 12-Aug K.IYVLLRR.Q sp|P84090|ERH_HUMAN 1 931.5967 2.28 28769 12582 2 931.59643 466.8056 Enhancer of rudimentary homolog OS=Homo sapiens OX=9606 GN=ERH PE=1 SV=1 10.84 2514.1 - 817686 - - - -0.3124 - 1.511 0.196 - 181.2 1 2 0 -0.0003 7 0 0 0 5.00E+07 2.19E+07 - - - 1.7965 0.9998 221125_WJC_METTL3_EV_vs_WT_F03.12583.12583.2 0.00737 18-Oct R.ANPLSLDSAR[166.11].W "sp|O14654|IRS4_HUMAN,tr|A0A804CF45|A0A804CF45_HUMAN" 2 1052.549 1.05 28770 12583 2 1052.548402 527.2818 Insulin receptor substrate 4 OS=Homo sapiens OX=9606 GN=IRS4 PE=1 SV=1 5.88 2514.1 - 9.33E+06 - - - -0.5615 - 1.836 0.427 - 306.4 1 2 0 -0.0006 10 0 0 0 3.27E+08 3.11E+08 - - - 3.8906 0.9992 221125_WJC_METTL3_EV_vs_WT_F03.12585.12585.2 1.2 14/24 R.TPTAPAVNLAGAR[166.11].T sp|Q9UQ35|SRRM2_HUMAN 1 1247.6862 0.99 28772 12585 2 1247.68464 624.8504 Serine\arginine repetitive matrix protein 2 OS=Homo sapiens OX=9606 GN=SRRM2 PE=1 SV=2 9.41 2514.3 - 802672 - - - -1.2142 - 2.523 0.188 - 594.2 1 2 0 -0.0015 13 0 0 0 9.91E+07 1.01E+08 - - - 2.8043 1 221125_WJC_METTL3_EV_vs_WT_F03.12586.12586.2 1.09E-06 19/30 A.TAAAAAAAAYSDGYGR.V "sp|O43251|RFOX2_HUMAN,tr|B0QYV1|B0QYV1_HUMAN,tr|A0A0G2JRD1|A0A0G2JRD1_HUMAN,tr|A0A0G2JRA5|A0A0G2JRA5_HUMAN,tr|S4R3K7|S4R3K7_HUMAN" 5 1485.6848 1.37 28773 12586 2 1485.686781 743.8497 RNA binding protein fox-1 homolog 2 OS=Homo sapiens OX=9606 GN=RBFOX2 PE=1 SV=3 5.5 2514.4 - 628831 - - - 1.3193 - 3.774 0.644 - 1499.5 1 1 0 0.002 16 0 0 0 1.94E+07 1.41E+07 - - - 7.0623 1 221125_WJC_METTL3_EV_vs_WT_F03.12587.12587.2 1.56E-09 17/30 A.TAAAAAAAAYSDGYGR[166.11].V "sp|O43251|RFOX2_HUMAN,tr|B0QYV1|B0QYV1_HUMAN,tr|A0A0G2JRD1|A0A0G2JRD1_HUMAN,tr|A0A0G2JRA5|A0A0G2JRA5_HUMAN,tr|S4R3K7|S4R3K7_HUMAN" 5 1495.6931 1.37 28774 12587 2 1495.688138 748.8538 RNA binding protein fox-1 homolog 2 OS=Homo sapiens OX=9606 GN=RBFOX2 PE=1 SV=3 5.5 2514.6 - 491552 - - - -3.3115 - 3.616 0.562 - 1149.2 1 1 0 -0.005 16 0 0 0 1.94E+07 1.41E+07 - - - 6.3505 0.9998 221125_WJC_METTL3_EV_vs_WT_F03.12590.12590.2 0.000375 18-Oct K.GLSQSALPYR.R "sp|P62277|RS13_HUMAN,tr|J3KMX5|J3KMX5_HUMAN,tr|E9PS50|E9PS50_HUMAN" 3 1090.5771 0.97 28775 12590 2 1090.577651 546.2958 40S ribosomal protein S13 OS=Homo sapiens OX=9606 GN=RPS13 PE=1 SV=2 8.75 2515 - 8.60E+06 - - - 0.4979 - 2.015 0.404 - 495.1 1 2 0 0.0005 10 0 0 0 9.39E+08 9.67E+08 - - - 3.9804 0.9999 221125_WJC_METTL3_EV_vs_WT_F03.12592.12592.2 0.000125 20-Dec R.IWDTASGQC[160.03]LK.T sp|P61964|WDR5_HUMAN 1 1277.6074 1.33 28777 12592 2 1277.607983 639.811 WD repeat-containing protein 5 OS=Homo sapiens OX=9606 GN=WDR5 PE=1 SV=1 5.83 2515.1 - 847223 - - - 0.4391 - 2.22 0.464 - 485.7 1 2 0 0.0006 11 0 0 0 2.94E+07 2.20E+07 - - - 4.6254 0.9993 221125_WJC_METTL3_EV_vs_WT_F03.12593.12593.2 0.00161 24-Sep K.FLEEHPGGEEVLR.E sp|P00167|CYB5_HUMAN 1 1510.7416 3.13 28778 12593 2 1510.74064 756.3781 Cytochrome b5 OS=Homo sapiens OX=9606 GN=CYB5A PE=1 SV=2 4.48 2515.3 - 466958 - - - -0.6401 - 1.669 0.329 - 153.2 1 2 0 -0.001 13 0 0 0 8.73E+06 2.79E+06 - - - 2.7853 0.9873 221125_WJC_METTL3_EV_vs_WT_F03.12597.12597.2 2.43 16-Jun R.TEIVFTGEK.E "sp|Q00341|VIGLN_HUMAN,tr|A0A024R4E5|A0A024R4E5_HUMAN,tr|H7C0A4|H7C0A4_HUMAN,tr|H0Y394|H0Y394_HUMAN" 4 1022.5284 1.29 28780 12597 2 1022.527611 512.2715 Vigilin OS=Homo sapiens OX=9606 GN=HDLBP PE=1 SV=2 4.53 2515.7 - 4.09E+06 - - - -0.798 - 1.218 0.124 - 106.4 1 2 0 -0.0008 9 0 0 0 5.61E+07 4.35E+07 - - - 0.5271 0.9973 221125_WJC_METTL3_EV_vs_WT_F03.12601.12601.2 0.298 14-Aug K.TYFNGDLK.N "sp|Q8IWC1|MA7D3_HUMAN,tr|A0A0A0MRP0|A0A0A0MRP0_HUMAN" 2 956.4603 1.21 28784 12601 2 956.459562 479.2374 MAP7 domain-containing protein 3 OS=Homo sapiens OX=9606 GN=MAP7D3 PE=1 SV=2 5.5 2516.1 - 1.06E+06 - - - -0.8207 - 1.329 0.236 - 210.3 1 2 0 -0.0008 8 0 0 0 3.66E+07 3.02E+07 - - - 1.6417 0.9993 221125_WJC_METTL3_EV_vs_WT_F03.12606.12606.2 0.0764 16-Sep K.FEVIEKPQA.- sp|P18859|ATP5J_HUMAN 1 1059.5601 19.41 28787 12606 2 1059.561427 530.7873 "ATP synthase-coupling factor 6, mitochondrial OS=Homo sapiens OX=9606 GN=ATP5PF PE=1 SV=1" 4.53 2516.6 - 1.59E+06 - - - 1.2892 - 1.875 0.307 - 294.6 1 2 0 0.0014 9 0 0 0 1.56E+08 8.04E+06 - - - 3.1267 0.9999 221125_WJC_METTL3_EV_vs_WT_F03.12607.12607.2 0.000153 20-Oct R.LSPADDELYQR[166.11].T sp|Q9BU61|NDUF3_HUMAN 1 1315.6284 1.74 28788 12607 2 1315.628788 658.8215 NADH dehydrogenase [ubiquinone] 1 alpha subcomplex assembly factor 3 OS=Homo sapiens OX=9606 GN=NDUFAF3 PE=1 SV=1 4.03 2516.7 - 4.72E+06 - - - 0.3215 - 1.898 0.518 - 506.6 1 2 0 0.0004 11 0 0 0 3.29E+08 1.89E+08 - - - 4.6003 0.9785 221125_WJC_METTL3_EV_vs_WT_F03.12609.12609.2 0.125 14-Aug K.DPFAHLPK.S sp|P26641|EF1G_HUMAN 1 923.4865 0.98 28790 12609 2 923.489604 462.7505 Elongation factor 1-gamma OS=Homo sapiens OX=9606 GN=EEF1G PE=1 SV=3 6.74 2516.9 - 412389 - - - 3.359 - 1.137 0.257 - 145.1 1 2 0 0.0031 8 0 0 0 1.45E+07 1.47E+07 - - - 1.3255 0.9997 221125_WJC_METTL3_EV_vs_WT_F03.12612.12612.2 0.000774 16-Oct R.QLQQLQQLR[166.11].D sp|O43290|SNUT1_HUMAN 1 1163.665 1.58 28791 12612 2 1163.663699 582.8398 U4\U6.U5 tri-snRNP-associated protein 1 OS=Homo sapiens OX=9606 GN=SART1 PE=1 SV=1 9.75 2517.3 - 1.48E+06 - - - -1.1395 - 2.126 0.335 - 524 1 2 0 -0.0013 9 0 0 0 8.11E+07 5.14E+07 - - - 3.697 0.9998 221125_WJC_METTL3_EV_vs_WT_F03.12613.12613.2 0.000285 18-Sep R.NVELTEVGPR[166.11].F "sp|Q96G21|IMP4_HUMAN,tr|E7ENR5|E7ENR5_HUMAN,tr|H0Y714|H0Y714_HUMAN,tr|B9A008|B9A008_HUMAN" 4 1122.5909 1.08 28792 12613 2 1122.590723 562.3027 U3 small nucleolar ribonucleoprotein protein IMP4 OS=Homo sapiens OX=9606 GN=IMP4 PE=1 SV=1 4.53 2517.3 - 1.96E+06 - - - -0.1203 - 1.916 0.431 - 293.3 1 2 0 -0.0001 10 0 0 0 4.63E+07 4.28E+07 - - - 4.0393 0.9997 221125_WJC_METTL3_EV_vs_WT_F03.12614.12614.3 0.00453 13/40 K.ILKPTDENLLK.Y "sp|Q9P015|RM15_HUMAN,tr|E5RIZ4|E5RIZ4_HUMAN" 2 1282.7497 1.47 28793 12614 3 1282.748138 428.5905 "39S ribosomal protein L15, mitochondrial OS=Homo sapiens OX=9606 GN=MRPL15 PE=1 SV=1" 6.07 2517.5 - 1.04E+06 - - - -1.1811 - 2.003 0.344 - 129.7 1 2 0 -0.0015 11 0 0 0 2.77E+07 1.88E+07 - - - 4.3482 0.9998 221125_WJC_METTL3_EV_vs_WT_F03.12615.12615.3 0.00475 Oct-36 K.IAGYVTHLMK[136.11].R "sp|P08708|RS17_HUMAN,tr|H3BNC9|H3BNC9_HUMAN,tr|H0YN88|H0YN88_HUMAN,tr|A0A075B716|A0A075B716_HUMAN" 4 1139.6253 0.001 28794 12615 3 1139.624006 380.8824 40S ribosomal protein S17 OS=Homo sapiens OX=9606 GN=RPS17 PE=1 SV=2 8.6 2517.6 - 500487 - - - -1.0925 - 1.895 0.364 - 93 1 2 0 -0.0012 10 0 0 0 0.00E+00 1.53E+09 - - - 4.4647 0.9999 221125_WJC_METTL3_EV_vs_WT_F03.12616.12616.2 3.97E-05 22-Nov K.LVPLNQESVEER.V "sp|Q8N1F7|NUP93_HUMAN,tr|H3BRD9|H3BRD9_HUMAN,tr|H3BVG0|H3BVG0_HUMAN,tr|H3BV15|H3BV15_HUMAN" 4 1411.7307 2.34 28795 12616 2 1411.729741 706.8726 Nuclear pore complex protein Nup93 OS=Homo sapiens OX=9606 GN=NUP93 PE=1 SV=2 4.25 2517.7 - 493959 - - - -0.685 - 1.912 0.543 - 351.8 1 2 0 -0.001 12 0 0 0 1.60E+08 6.87E+07 - - - 4.7567 0.9998 221125_WJC_METTL3_EV_vs_WT_F03.12619.12619.2 0.0194 16-Dec R.TEIVFTGEK[136.11].E "sp|Q00341|VIGLN_HUMAN,tr|A0A024R4E5|A0A024R4E5_HUMAN,tr|H7C0A4|H7C0A4_HUMAN,tr|H0Y394|H0Y394_HUMAN" 4 1030.5426 1.9 28796 12619 2 1030.541463 516.2786 Vigilin OS=Homo sapiens OX=9606 GN=HDLBP PE=1 SV=2 4.53 2518.1 - 1.57E+06 - - - -1.1295 - 2.305 0.379 - 707.8 1 2 0 -0.0012 9 0 0 0 8.54E+07 4.50E+07 - - - 4.2559 0.976 221125_WJC_METTL3_EV_vs_WT_F03.12620.12620.2 0.00121 14-Jul M.GSYGPFGR[166.11].M "sp|Q8ND56|LS14A_HUMAN,tr|A0A140TA76|A0A140TA76_HUMAN,tr|K7EMZ9|K7EMZ9_HUMAN" 3 849.4009 0.97 28797 12620 2 849.400416 425.7077 Protein LSM14 homolog A OS=Homo sapiens OX=9606 GN=LSM14A PE=1 SV=3 8.75 2518.2 - 1.75E+06 - - - -0.5368 - 1.332 0.455 - 147.3 1 1 0 -0.0005 8 0 0 0 5.62E+07 5.77E+07 - - - 3.2661 0.9996 221125_WJC_METTL3_EV_vs_WT_F03.12621.12621.2 0.00472 24-Oct R.LASTGSGQSFLAR.Q sp|Q86VS8|HOOK3_HUMAN 1 1293.6677 10.72 28798 12621 2 1293.665735 647.8411 Protein Hook homolog 3 OS=Homo sapiens OX=9606 GN=HOOK3 PE=1 SV=2 9.75 2518.2 - 1.89E+06 - - - -1.5298 - 2.03 0.408 - 217.3 1 2 0 -0.002 13 0 0 0 3.92E+07 3.66E+06 - - - 3.8711 0.9407 221125_WJC_METTL3_EV_vs_WT_F03.12622.12622.2 2.63 16-Jul R.GVSGVDLYR.S "sp|Q9Y618|NCOR2_HUMAN,tr|C9J7T7|C9J7T7_HUMAN,tr|C9JE98|C9JE98_HUMAN,tr|C9J0Q5|C9J0Q5_HUMAN,tr|A0A384DVL6|A0A384DVL6_HUMAN" 5 964.4978 7.15 28799 12622 2 964.500292 483.2562 Nuclear receptor corepressor 2 OS=Homo sapiens OX=9606 GN=NCOR2 PE=1 SV=3 5.84 2518.3 - 1.33E+06 - - - 2.5889 - 1.02 0.153 - 89.5 1 2 0 0.0025 9 0 0 0 1.62E+08 2.26E+07 - - - 0.2276 0.9998 221125_WJC_METTL3_EV_vs_WT_F03.12623.12623.2 3.58E-05 22-Dec K.LVPLNQESVEER.V "sp|Q8N1F7|NUP93_HUMAN,tr|H3BRD9|H3BRD9_HUMAN,tr|H3BVG0|H3BVG0_HUMAN,tr|H3BV15|H3BV15_HUMAN" 4 1411.7307 2.34 28800 12623 2 1411.72859 706.8726 Nuclear pore complex protein Nup93 OS=Homo sapiens OX=9606 GN=NUP93 PE=1 SV=2 4.25 2518.4 - 605204 - - - -1.5003 - 1.975 0.544 - 287.5 1 2 0 -0.0021 12 0 0 0 1.60E+08 6.87E+07 - - - 4.849 0.9997 221125_WJC_METTL3_EV_vs_WT_F03.12625.12625.2 7.03E-05 22-Nov K.LVPLNQESVEER[166.11].V "sp|Q8N1F7|NUP93_HUMAN,tr|H3BRD9|H3BRD9_HUMAN,tr|H3BVG0|H3BVG0_HUMAN,tr|H3BV15|H3BV15_HUMAN" 4 1421.739 2.34 28802 12625 2 1421.735638 711.8768 Nuclear pore complex protein Nup93 OS=Homo sapiens OX=9606 GN=NUP93 PE=1 SV=2 4.25 2518.7 - 367895 - - - -2.3492 - 2.114 0.546 - 448.7 1 2 0 -0.0033 12 0 0 0 1.60E+08 6.87E+07 - - - 5.0424 0.9978 221125_WJC_METTL3_EV_vs_WT_F03.12630.12630.2 0.128 12-Aug R.SSGAFWK.Y "sp|P25311|ZA2G_HUMAN,tr|C9JEV0|C9JEV0_HUMAN" 2 781.3759 722.99 28805 12630 2 781.374973 391.6952 Zinc-alpha-2-glycoprotein OS=Homo sapiens OX=9606 GN=AZGP1 PE=1 SV=2 8.47 2519.3 - 2.09E+06 - - - -1.1723 - 1.435 0.233 - 319.3 1 2 0 -0.0009 7 0 0 0 2.08E+08 2.88E+05 - - - 1.906 0.9984 221125_WJC_METTL3_EV_vs_WT_F03.12631.12631.2 0.00829 14-Jul K.TYFNGDLK[136.11].N "sp|Q8IWC1|MA7D3_HUMAN,tr|A0A0A0MRP0|A0A0A0MRP0_HUMAN" 2 964.4745 1.9 28806 12631 2 964.472734 483.2445 MAP7 domain-containing protein 3 OS=Homo sapiens OX=9606 GN=MAP7D3 PE=1 SV=2 5.5 2519.3 - 1.22E+06 - - - -1.8798 - 1.261 0.379 - 137.3 1 2 0 -0.0018 8 0 0 0 3.48E+07 1.83E+07 - - - 2.5391 0.9999 221125_WJC_METTL3_EV_vs_WT_F03.12632.12632.2 1.69E-05 20-Oct R.LSPADDELYQR.T sp|Q9BU61|NDUF3_HUMAN 1 1305.6201 1.78 28807 12632 2 1305.619267 653.8173 NADH dehydrogenase [ubiquinone] 1 alpha subcomplex assembly factor 3 OS=Homo sapiens OX=9606 GN=NDUFAF3 PE=1 SV=1 4.03 2519.4 - 8.15E+06 - - - -0.6342 - 2.004 0.551 - 409.7 1 2 0 -0.0008 11 0 0 0 3.46E+08 1.94E+08 - - - 4.991 0.9993 221125_WJC_METTL3_EV_vs_WT_F03.12633.12633.2 0.000148 20-Dec R.VAEELALEQAK.K "sp|Q9NX63|MIC19_HUMAN,tr|A0A286YEX5|A0A286YEX5_HUMAN,tr|F8WAR4|F8WAR4_HUMAN,tr|C9JRZ6|C9JRZ6_HUMAN" 4 1199.6398 2.75 28808 12633 2 1199.643692 600.8272 MICOS complex subunit MIC19 OS=Homo sapiens OX=9606 GN=CHCHD3 PE=1 SV=1 4.25 2519.5 - 1.03E+06 - - - 3.271 - 2.488 0.453 - 672.9 1 2 0 0.0039 11 0 0 0 4.17E+08 1.52E+08 - - - 4.8514 0.9294 221125_WJC_METTL3_EV_vs_WT_F03.12636.12636.2 0.541 14-Jul K.QYLSIAER[166.11].A "sp|P28360|MSX1_HUMAN,sp|P35548|MSX2_HUMAN" 2 988.5217 1.19 28809 12636 2 988.52608 495.2681 Homeobox protein MSX-1 OS=Homo sapiens OX=9606 GN=MSX1 PE=1 SV=3 6 2519.9 - 935988 - - - 4.4157 - 1.286 0.162 - 178.7 1 2 0 0.0044 8 0 0 0 7.98E+07 6.69E+07 - - - 0.9948 0.9536 221125_WJC_METTL3_EV_vs_WT_F03.12638.12638.2 0.0133 28-Sep R.HLLPTSGAAATAAAA.A "sp|Q9BWF3|RBM4_HUMAN,tr|E9PB51|E9PB51_HUMAN" 2 1321.699 - 28811 12638 2 1321.698549 661.8568 RNA-binding protein 4 OS=Homo sapiens OX=9606 GN=RBM4 PE=1 SV=1 6.74 2520.1 - 1.21E+06 - - - -0.3518 - 1.612 0.318 - 107.2 1 1 0 -0.0005 15 0 0 0 - - - - - 2.5635 1 221125_WJC_METTL3_EV_vs_WT_F03.12639.12639.2 6.90E-10 24-Nov C.VLASNC[160.03]DEPMYVK.L sp|P25398|RS12_HUMAN 1 1524.6953 1.67 28812 12639 2 1524.692259 763.3549 40S ribosomal protein S12 OS=Homo sapiens OX=9606 GN=RPS12 PE=1 SV=3 4.37 2520.2 - 502431 - - - -1.9624 - 2.483 0.681 - 342.5 1 1 0 -0.003 13 0 0 0 9.01E+06 5.40E+06 - - - 6.4041 1 221125_WJC_METTL3_EV_vs_WT_F03.12640.12640.2 5.24E-07 24-Dec C.VLASNC[160.03]DEPMYVK[136.11].L sp|P25398|RS12_HUMAN 1 1532.7095 1.67 28813 12640 2 1532.708663 767.362 40S ribosomal protein S12 OS=Homo sapiens OX=9606 GN=RPS12 PE=1 SV=3 4.37 2520.4 - 258513 - - - -0.5141 - 2.34 0.629 - 479.6 1 1 0 -0.0008 13 0 0 0 9.01E+06 5.40E+06 - - - 5.8685 0.9994 221125_WJC_METTL3_EV_vs_WT_F03.12644.12644.2 0.000821 18-Aug R.ANPLSLDSAR.W "sp|O14654|IRS4_HUMAN,tr|A0A804CF45|A0A804CF45_HUMAN" 2 1042.5407 1.05 28815 12644 2 1042.541078 522.2776 Insulin receptor substrate 4 OS=Homo sapiens OX=9606 GN=IRS4 PE=1 SV=1 5.88 2520.8 - 5.04E+06 - - - 0.3405 - 1.584 0.351 - 278.8 1 2 0 0.0004 10 0 0 0 3.26E+08 3.11E+08 - - - 2.9172 0.9995 221125_WJC_METTL3_EV_vs_WT_F03.12646.12646.2 0.00483 14-Aug K.FEMEQNLR.Q "sp|P35527|K1C9_HUMAN,tr|K7EQQ3|K7EQQ3_HUMAN" 2 1065.4913 2015.51 28817 12646 2 1065.491695 533.7529 "Keratin, type I cytoskeletal 9 OS=Homo sapiens OX=9606 GN=KRT9 PE=1 SV=3" 4.53 2520.9 - 1.90E+06 - - - 0.3426 - 1.598 0.341 - 224.7 1 2 0 0.0004 8 0 0 0 1.97E+09 9.80E+05 - - - 2.9732 0.9998 221125_WJC_METTL3_EV_vs_WT_F03.12648.12648.2 0.0596 13/20 R.LSQLEGVNVER[166.11].Y sp|Q96QK1|VPS35_HUMAN 1 1252.6651 0.22 28819 12648 2 1252.664555 627.3398 Vacuolar protein sorting-associated protein 35 OS=Homo sapiens OX=9606 GN=VPS35 PE=1 SV=2 4.53 2521.1 - 845574 - - - -0.4231 - 2.553 0.303 - 642.9 1 2 0 -0.0005 11 0 0 0 3.42E+06 1.55E+07 - - - 3.8143 0.9997 221125_WJC_METTL3_EV_vs_WT_F03.12651.12651.2 0.0136 18-Aug R.LGFITNNSSK.T sp|A6NDG6|PGP_HUMAN 1 1079.5611 2.63 28820 12651 2 1079.561263 540.7878 Glycerol-3-phosphate phosphatase OS=Homo sapiens OX=9606 GN=PGP PE=1 SV=1 8.75 2521.5 - 1.20E+06 - - - 0.1288 - 1.557 0.428 - 161.3 1 2 0 0.0001 10 0 0 0 1.31E+08 4.97E+07 - - - 3.438 0.9999 221125_WJC_METTL3_EV_vs_WT_F03.12652.12652.2 0.00233 22-Sep R.IYYGTEAQIGER.T sp|P22735|TGM1_HUMAN 1 1398.6779 999 28821 12652 2 1398.677072 700.3462 Protein-glutamine gamma-glutamyltransferase K OS=Homo sapiens OX=9606 GN=TGM1 PE=1 SV=4 4.53 2521.7 - 869227 - - - -0.6242 - 2.129 0.502 - 237.8 1 2 0 -0.0009 12 0 0 0 4.73E+07 0.00E+00 - - - 4.7367 0.9986 221125_WJC_METTL3_EV_vs_WT_F03.12655.12655.2 0.129 16-Aug K.SPLQSVVVR.R "sp|Q9Y2W1|TR150_HUMAN,tr|A0A3B3ITZ9|A0A3B3ITZ9_HUMAN" 2 983.5764 2.3 28824 12655 2 983.576055 492.7955 Thyroid hormone receptor-associated protein 3 OS=Homo sapiens OX=9606 GN=THRAP3 PE=1 SV=2 9.47 2522 - 526911 - - - -0.3304 - 1.467 0.259 - 151.6 1 2 0 -0.0003 9 0 0 0 2.02E+09 8.79E+08 - - - 2.0625 0.9995 221125_WJC_METTL3_EV_vs_WT_F03.12657.12657.2 0.323 16-Aug R.QLQQLQQLR.D sp|O43290|SNUT1_HUMAN 1 1153.6568 1.58 28825 12657 2 1153.655364 577.8357 U4\U6.U5 tri-snRNP-associated protein 1 OS=Homo sapiens OX=9606 GN=SART1 PE=1 SV=1 9.75 2522.2 - 2.45E+06 - - - -1.2057 - 2.017 0.318 - 374.2 1 2 0 -0.0014 9 0 0 0 8.11E+07 5.14E+07 - - - 3.4191 0.9996 221125_WJC_METTL3_EV_vs_WT_F03.12658.12658.2 4.40E-05 16-Oct K.NDDGLVEIK.V tr|A8MXP9|A8MXP9_HUMAN 1 1001.5029 1.57 28826 12658 2 1001.501677 501.7587 Matrin-3 OS=Homo sapiens OX=9606 GN=MATR3 PE=1 SV=1 4.03 2522.3 - 1.93E+06 - - - -1.2611 - 1.821 0.383 - 365.4 1 2 0 -0.0013 9 0 0 0 4.88E+07 3.11E+07 - - - 3.6035 0.9981 221125_WJC_METTL3_EV_vs_WT_F03.12659.12659.2 0.157 18-Sep K.VSVPSTVISR.V "sp|O75179|ANR17_HUMAN,tr|H0YM23|H0YM23_HUMAN" 2 1043.5975 0.58 28827 12659 2 1043.597502 522.806 Ankyrin repeat domain-containing protein 17 OS=Homo sapiens OX=9606 GN=ANKRD17 PE=1 SV=3 9.72 2522.3 - 3.19E+06 - - - -0.0067 - 1.427 0.242 - 274.6 1 2 0 0 10 0 0 0 8.51E+07 1.46E+08 - - - 1.8209 0.9998 221125_WJC_METTL3_EV_vs_WT_F03.12660.12660.2 0.0032 18-Dec K.IAGYVTHLMK[136.11].R "sp|P08708|RS17_HUMAN,tr|H3BNC9|H3BNC9_HUMAN,tr|H0YN88|H0YN88_HUMAN,tr|A0A075B716|A0A075B716_HUMAN" 4 1139.6253 1.15 28828 12660 2 1139.624284 570.8199 40S ribosomal protein S17 OS=Homo sapiens OX=9606 GN=RPS17 PE=1 SV=2 8.6 2522.4 - 1.95E+06 - - - -0.8485 - 2.347 0.402 - 402.9 1 2 0 -0.001 10 0 0 0 5.86E+08 5.07E+08 - - - 4.3912 0.9996 221125_WJC_METTL3_EV_vs_WT_F03.12661.12661.3 0.00278 13/40 R.TLRPALVGVVK.E sp|Q9HAV7|GRPE1_HUMAN 1 1151.739 0.88 28829 12661 3 1151.737019 384.9203 "GrpE protein homolog 1, mitochondrial OS=Homo sapiens OX=9606 GN=GRPEL1 PE=1 SV=2" 11 2522.5 - 528335 - - - -1.7452 - 1.811 0.373 - 196.3 1 2 0 -0.002 11 0 0 0 6.09E+07 6.92E+07 - - - 4.3851 0.9993 221125_WJC_METTL3_EV_vs_WT_F03.12665.12665.2 0.0269 14-Oct K.QYLSIAER.A "sp|P28360|MSX1_HUMAN,sp|P35548|MSX2_HUMAN" 2 978.5134 1.25 28831 12665 2 978.512927 490.264 Homeobox protein MSX-1 OS=Homo sapiens OX=9606 GN=MSX1 PE=1 SV=3 6 2523 - 3.26E+06 - - - -0.5294 - 1.755 0.264 - 418.6 1 2 0 -0.0005 8 0 0 0 7.98E+07 6.39E+07 - - - 2.6871 0.9829 221125_WJC_METTL3_EV_vs_WT_F03.12666.12666.2 1.01 14-Sep K.IKNYILMR.M "sp|P43243|MATR3_HUMAN,tr|B3KM87|B3KM87_HUMAN,tr|A8MXP9|A8MXP9_HUMAN,tr|A0A0R4J2E8|A0A0R4J2E8_HUMAN,tr|H0Y8T4|H0Y8T4_HUMAN,tr|D6REM6|D6REM6_HUMAN" 6 1049.6056 1.4 28832 12666 2 1049.605164 525.8101 Matrin-3 OS=Homo sapiens OX=9606 GN=MATR3 PE=1 SV=2 9.99 2523.1 - 2.99E+06 - - - -0.3887 - 1.828 0.155 - 252.9 1 2 1 -0.0004 8 0 0 0 2.06E+08 1.47E+08 - - - 2.005 0.9804 221125_WJC_METTL3_EV_vs_WT_F03.12667.12667.2 0.016 14-Jul R.GLPFGC[160.03]SK[136.11].E "sp|P55795|HNRH2_HUMAN,sp|P31942|HNRH3_HUMAN,sp|P31943|HNRH1_HUMAN,tr|E5RGH4|E5RGH4_HUMAN,tr|D6RIH9|D6RIH9_HUMAN,tr|D6RJ04|D6RJ04_HUMAN,tr|E5RGV0|E5RGV0_HUMAN,tr|D6RFM3|D6RFM3_HUMAN,tr|E9PCY7|E9PCY7_HUMAN,tr|D6RIT2|D6RIT2_HUMAN,tr|D6R9T0|D6R9T0_HUMAN,tr|D6RIU0|D6RIU0_HUMAN,tr|H0YAQ2|H0YAQ2_HUMAN,tr|D6RAM1|D6RAM1_HUMAN,tr|D6RBM0|D6RBM0_HUMAN,tr|G8JLB6|G8JLB6_HUMAN,tr|D6RDU3|D6RDU3_HUMAN" 17 872.4306 0.99 28833 12667 2 872.429709 437.2226 Heterogeneous nuclear ribonucleoprotein H2 OS=Homo sapiens OX=9606 GN=HNRNPH2 PE=1 SV=1 8.22 2523.1 - 8.23E+06 - - - -0.9915 - 1.149 0.112 - 159.5 1 2 0 -0.0009 8 0 0 0 2.90E+08 2.94E+08 - - - 0.2869 0.9992 221125_WJC_METTL3_EV_vs_WT_F03.12668.12668.2 0.0141 18-Sep R.GVVPFQAGSR.N "sp|Q7Z2W4|ZCCHV_HUMAN,tr|H7C5K1|H7C5K1_HUMAN,tr|C9J6P4|C9J6P4_HUMAN,tr|A0A7P0T8C6|A0A7P0T8C6_HUMAN" 4 1016.5403 0.15 28834 12668 2 1016.540542 509.2774 Zinc finger CCCH-type antiviral protein 1 OS=Homo sapiens OX=9606 GN=ZC3HAV1 PE=1 SV=3 9.75 2523.2 - 1.16E+06 - - - 0.2095 - 1.588 0.31 - 276.7 1 2 0 0.0002 10 0 0 0 2.59E+07 1.72E+08 - - - 2.6215 0.9997 221125_WJC_METTL3_EV_vs_WT_F03.12670.12670.2 0.0117 24-Sep R.GETAVPGAPEALR.A sp|A6NDG6|PGP_HUMAN 1 1266.6568 1.64 28836 12670 2 1266.657194 634.3357 Glycerol-3-phosphate phosphatase OS=Homo sapiens OX=9606 GN=PGP PE=1 SV=1 4.53 2523.4 - 587956 - - - 0.2992 - 1.87 0.425 - 159.2 1 2 0 0.0004 13 0 0 0 2.85E+07 1.73E+07 - - - 3.7864 0.9954 221125_WJC_METTL3_EV_vs_WT_F03.12672.12672.3 0.346 Oct-40 R.VAEELALEQAK.K "sp|Q9NX63|MIC19_HUMAN,tr|A0A286YEX5|A0A286YEX5_HUMAN,tr|F8WAR4|F8WAR4_HUMAN,tr|C9JRZ6|C9JRZ6_HUMAN" 4 1199.6398 0.02 28838 12672 3 1199.639798 400.8872 MICOS complex subunit MIC19 OS=Homo sapiens OX=9606 GN=CHCHD3 PE=1 SV=1 4.25 2523.7 - 319925 - - - 0.025 - 1.883 0.175 - 101.2 1 2 0 0 11 0 0 0 1.35E+07 8.21E+08 - - - 2.2889 0.9996 221125_WJC_METTL3_EV_vs_WT_F03.12675.12675.2 0.000473 14-Sep K.SC[160.03]NC[160.03]LLLK.V "sp|P06733|ENOA_HUMAN,tr|A0A2R8Y6G6|A0A2R8Y6G6_HUMAN" 2 1006.494 1.32 28839 12675 2 1006.492559 504.2543 Alpha-enolase OS=Homo sapiens OX=9606 GN=ENO1 PE=1 SV=2 7.79 2524.1 - 2.56E+06 - - - -1.4049 - 1.728 0.423 - 352.7 1 2 0 -0.0014 8 0 0 0 3.93E+08 2.97E+08 - - - 3.8145 0.999 221125_WJC_METTL3_EV_vs_WT_F03.12677.12677.2 0.104 18-Oct K.IEELLSGENR[166.11].G "sp|Q9NY93|DDX56_HUMAN,tr|H7BZN7|H7BZN7_HUMAN,tr|H7C3E9|H7C3E9_HUMAN" 3 1168.5963 0.55 28841 12677 2 1168.594136 585.3054 Probable ATP-dependent RNA helicase DDX56 OS=Homo sapiens OX=9606 GN=DDX56 PE=1 SV=1 4.25 2524.3 - 550371 - - - -1.8835 - 2.309 0.217 - 375.1 1 2 0 -0.0022 10 0 0 0 1.37E+07 2.50E+07 - - - 2.9789 0.9965 221125_WJC_METTL3_EV_vs_WT_F03.12678.12678.2 0.0034 24-Oct R.GETAVPGAPEALR[166.11].A sp|A6NDG6|PGP_HUMAN 1 1276.6651 1.63 28842 12678 2 1276.660797 639.3398 Glycerol-3-phosphate phosphatase OS=Homo sapiens OX=9606 GN=PGP PE=1 SV=1 4.53 2524.4 - 258804 - - - -3.3588 - 1.581 0.355 - 175.7 1 2 0 -0.0043 13 0 0 0 2.83E+07 1.73E+07 - - - 2.8373 0.9999 221125_WJC_METTL3_EV_vs_WT_F03.12680.12680.2 2.18E-05 13/22 R.ALEEANADLEVK.L "sp|P02533|K1C14_HUMAN,sp|P08779|K1C16_HUMAN,sp|P19012|K1C15_HUMAN,sp|P13646|K1C13_HUMAN,tr|K7EMD9|K7EMD9_HUMAN,tr|K7ERE3|K7ERE3_HUMAN" 6 1300.6511 8551.14 28843 12680 2 1300.650391 651.3328 "Keratin, type I cytoskeletal 14 OS=Homo sapiens OX=9606 GN=KRT14 PE=1 SV=4" 4 2524.7 - 5.07E+06 - - - -0.5151 - 2.78 0.461 - 541.4 1 2 0 -0.0007 12 0 0 0 1.16E+09 1.35E+05 - - - 5.136 0.9962 221125_WJC_METTL3_EV_vs_WT_F03.12682.12682.2 0.0856 16-Aug R.R[166.11]PC[160.03]TLSELE.- sp|P13674|P4HA1_HUMAN 1 1113.5364 1.59 28844 12682 2 1113.536368 557.7755 Prolyl 4-hydroxylase subunit alpha-1 OS=Homo sapiens OX=9606 GN=P4HA1 PE=1 SV=2 4.86 2524.9 - 4.56E+06 - - - -0.0099 - 1.709 0.095 - 187.4 1 2 0 0 9 0 0 0 2.57E+08 1.62E+08 - - - 1.2931 0.9978 221125_WJC_METTL3_EV_vs_WT_F03.12683.12683.2 0.000651 22-Nov K.LAEIGAPIQGNR.E "sp|Q13435|SF3B2_HUMAN,tr|E9PPJ0|E9PPJ0_HUMAN,tr|H0YCG1|H0YCG1_HUMAN,tr|E9PJ04|E9PJ04_HUMAN,tr|E9PJT3|E9PJT3_HUMAN" 5 1237.6779 0.97 28845 12683 2 1237.673413 619.8462 Splicing factor 3B subunit 2 OS=Homo sapiens OX=9606 GN=SF3B2 PE=1 SV=2 6 2524.9 - 2.94E+06 - - - -3.6132 - 2.145 0.335 - 233.3 1 2 0 -0.0045 12 0 0 0 9.84E+07 1.02E+08 - - - 3.5219 0.9984 221125_WJC_METTL3_EV_vs_WT_F03.12687.12687.2 0.0504 22-Oct R.ALEEANTELEVK.L "sp|Q04695|K1C17_HUMAN,tr|K7EPJ9|K7EPJ9_HUMAN" 2 1344.6773 999 28848 12687 2 1344.674993 673.3459 "Keratin, type I cytoskeletal 17 OS=Homo sapiens OX=9606 GN=KRT17 PE=1 SV=2" 4.09 2525.4 - 2.36E+06 - - - -1.6978 - 2.063 0.207 - 255.1 1 2 0 -0.0023 12 0 0 0 9.20E+07 0.00E+00 - - - 2.4746 0.9998 221125_WJC_METTL3_EV_vs_WT_F03.12689.12689.2 0.0857 14-Oct K.TEDLFENR[166.11].L "sp|Q92615|LAR4B_HUMAN,tr|H0Y641|H0Y641_HUMAN,tr|H0Y4V9|H0Y4V9_HUMAN" 3 1032.4752 1.19 28849 12689 2 1032.475441 517.2449 La-related protein 4B OS=Homo sapiens OX=9606 GN=LARP4B PE=1 SV=3 4.14 2525.6 - 1.60E+06 - - - 0.2731 - 2.251 0.347 - 578.9 1 2 0 0.0003 8 0 0 0 9.64E+08 8.13E+08 - - - 4.0509 0.999 221125_WJC_METTL3_EV_vs_WT_F03.12690.12690.2 0.0653 18-Sep R.LSQSLGLVSK[136.11].S "sp|Q9H6S0|YTDC2_HUMAN,tr|D6RF50|D6RF50_HUMAN,tr|D6RA70|D6RA70_HUMAN,tr|D6R9T8|D6R9T8_HUMAN" 4 1038.6165 0.99 28850 12690 2 1038.616458 520.3155 3'-5' RNA helicase YTHDC2 OS=Homo sapiens OX=9606 GN=YTHDC2 PE=1 SV=2 8.75 2525.7 - 918492 - - - -0.0019 - 1.859 0.219 - 165.8 1 2 0 0 10 0 0 0 1.72E+07 1.74E+07 - - - 2.3893 0.9998 221125_WJC_METTL3_EV_vs_WT_F03.12691.12691.2 0.00522 20-Oct R.LQDFYDSTAGK[136.11].F sp|Q7Z4H3|HDDC2_HUMAN 1 1251.5863 1.99 28851 12691 2 1251.585453 626.8004 5'-deoxynucleotidase HDDC2 OS=Homo sapiens OX=9606 GN=HDDC2 PE=1 SV=1 4.21 2525.8 - 996906 - - - -0.6624 - 1.799 0.476 - 338.7 1 2 0 -0.0008 11 0 0 0 1.23E+08 6.18E+07 - - - 4.1451 0.9133 221125_WJC_METTL3_EV_vs_WT_F03.12692.12692.2 5.36 14-Jun K.IAIDNLEK[136.11].A sp|Q12981|SEC20_HUMAN 1 922.5215 0.24 28852 12692 2 922.519685 462.268 Vesicle transport protein SEC20 OS=Homo sapiens OX=9606 GN=BNIP1 PE=1 SV=3 4.37 2525.9 - 609824 - - - -1.9642 - 1.084 0.069 - 71.6 2 2 0 -0.0018 8 0 0 0 6.16E+06 2.59E+07 - - - -0.3411 0.7801 221125_WJC_METTL3_EV_vs_WT_F03.12695.12695.2 0.735 14-Jun R.FPNK[136.11]PYLS.- sp|Q96BP2|CHCH1_HUMAN 1 972.516 1.74 28854 12695 2 972.520492 487.2653 Coiled-coil-helix-coiled-coil-helix domain-containing protein 1 OS=Homo sapiens OX=9606 GN=CHCHD1 PE=1 SV=1 8.59 2526.3 - 1.46E+06 - - - 4.6004 - 1.13 0.108 - 81.5 1 2 0 0.0045 8 0 0 0 9.12E+07 5.25E+07 - - - 0.2059 0.9998 221125_WJC_METTL3_EV_vs_WT_F03.12696.12696.2 0.00982 22-Nov R.AQPSVSLGAAYR.A sp|Q96PK6|RBM14_HUMAN 1 1218.6357 1.78 28855 12696 2 1218.635718 610.3251 RNA-binding protein 14 OS=Homo sapiens OX=9606 GN=RBM14 PE=1 SV=2 8.79 2526.4 - 1.47E+06 - - - 0.0263 - 2.17 0.427 - 460.4 1 2 0 0 12 0 0 0 1.48E+09 8.32E+08 - - - 4.2333 0.98 221125_WJC_METTL3_EV_vs_WT_F03.12699.12699.2 0.00336 12-Jul L.KNYILMR.M "sp|P43243|MATR3_HUMAN,tr|B3KM87|B3KM87_HUMAN,tr|A8MXP9|A8MXP9_HUMAN,tr|A0A0R4J2E8|A0A0R4J2E8_HUMAN,tr|H0Y8T4|H0Y8T4_HUMAN,tr|D6REM6|D6REM6_HUMAN" 6 936.5215 1.94 28858 12699 2 936.520949 469.268 Matrin-3 OS=Homo sapiens OX=9606 GN=MATR3 PE=1 SV=2 9.99 2526.6 - 1.30E+06 - - - -0.5969 - 1.65 0.387 - 223.2 1 1 0 -0.0006 7 0 0 0 4.33E+07 2.23E+07 - - - 3.4859 0.9987 221125_WJC_METTL3_EV_vs_WT_F03.12700.12700.2 0.0623 16-Sep R.ISGTSIAFK[136.11].N "sp|P27448|MARK3_HUMAN,sp|Q9P0L2|MARK1_HUMAN,tr|A0A7I2V3I9|A0A7I2V3I9_HUMAN,tr|H0YIY6|H0YIY6_HUMAN,tr|A0A7I2V550|A0A7I2V550_HUMAN,tr|A0A7I2V5G3|A0A7I2V5G3_HUMAN,tr|A0A7I2YQF4|A0A7I2YQF4_HUMAN,tr|A0A7I2YQF7|A0A7I2YQF7_HUMAN,tr|A0A7I2V4K8|A0A7I2V4K8_HUMAN,tr|A0A087X0I6|A0A087X0I6_HUMAN,tr|A0A7I2V2U9|A0A7I2V2U9_HUMAN,tr|A0A7I2V4G7|A0A7I2V4G7_HUMAN,tr|H0YNV4|H0YNV4_HUMAN,tr|A0A7I2V2N8|A0A7I2V2N8_HUMAN,tr|H0YJI9|H0YJI9_HUMAN,tr|A0A7I2V409|A0A7I2V409_HUMAN,tr|A0A7I2V549|A0A7I2V549_HUMAN,tr|A0A7I2V3B9|A0A7I2V3B9_HUMAN,tr|A0A7I2V602|A0A7I2V602_HUMAN,tr|A0A7I2V639|A0A7I2V639_HUMAN,tr|A0A7I2YQC1|A0A7I2YQC1_HUMAN,tr|B4DIB3|B4DIB3_HUMAN,tr|A0A7I2V2E3|A0A7I2V2E3_HUMAN,tr|J3KNR0|J3KNR0_HUMAN,tr|H0YKP9|H0YKP9_HUMAN" 25 930.5266 0.85 28859 12700 2 930.525115 466.2706 MAP\microtubule affinity-regulating kinase 3 OS=Homo sapiens OX=9606 GN=MARK3 PE=1 SV=5 8.75 2526.7 - 965349 - - - -1.5776 - 1.81 0.245 - 124 1 2 0 -0.0015 9 0 0 0 3.51E+07 4.14E+07 - - - 2.5666 0.9992 221125_WJC_METTL3_EV_vs_WT_F03.12701.12701.2 0.00705 16-Nov K.SPLQSVVVR[166.11].R "sp|Q9Y2W1|TR150_HUMAN,tr|A0A3B3ITZ9|A0A3B3ITZ9_HUMAN" 2 993.5847 2.47 28860 12701 2 993.585394 497.7996 Thyroid hormone receptor-associated protein 3 OS=Homo sapiens OX=9606 GN=THRAP3 PE=1 SV=2 9.47 2526.8 - 864719 - - - 0.7488 - 1.747 0.282 - 307.5 1 2 0 0.0007 9 0 0 0 3.36E+09 1.36E+09 - - - 2.7377 0.9998 221125_WJC_METTL3_EV_vs_WT_F03.12704.12704.2 0.0525 20-Oct R.LQDFYDSTAGK.F sp|Q7Z4H3|HDDC2_HUMAN 1 1243.5721 2.02 28861 12704 2 1243.570281 622.7933 5'-deoxynucleotidase HDDC2 OS=Homo sapiens OX=9606 GN=HDDC2 PE=1 SV=1 4.21 2527.2 - 3.23E+06 - - - -1.4482 - 2.263 0.456 - 282.1 1 2 0 -0.0018 11 0 0 0 1.23E+08 6.08E+07 - - - 4.6178 0.9988 221125_WJC_METTL3_EV_vs_WT_F03.12706.12706.2 0.18 16-Aug R.RPC[160.03]TLSELE.- sp|P13674|P4HA1_HUMAN 1 1103.5281 1.6 28863 12706 2 1103.527661 552.7713 Prolyl 4-hydroxylase subunit alpha-1 OS=Homo sapiens OX=9606 GN=P4HA1 PE=1 SV=2 4.86 2527.3 - 9.48E+06 - - - -0.406 - 1.734 0.211 - 221.5 1 2 0 -0.0004 9 0 0 0 2.59E+08 1.62E+08 - - - 2.1917 0.8539 221125_WJC_METTL3_EV_vs_WT_F03.12707.12707.2 0.07 20-Aug K.ATIAGGGVIPH.L "sp|P0C0S5|H2AZ_HUMAN,sp|Q71UI9|H2AV_HUMAN" 2 991.5451 - 28864 12707 2 991.544692 496.7798 Histone H2A.Z OS=Homo sapiens OX=9606 GN=H2AZ1 PE=1 SV=2 6.79 2527.4 - 2.62E+06 - - - -0.3913 - 1.327 0.233 - 136.5 1 1 0 -0.0004 11 0 0 0 - - - - - 1.5272 0.9998 221125_WJC_METTL3_EV_vs_WT_F03.12709.12709.2 7.62E-06 24-Dec K.LDPGSEETQTLVR[166.11].E sp|P26641|EF1G_HUMAN 1 1453.7288 1.58 28866 12709 2 1453.72728 727.8717 Elongation factor 1-gamma OS=Homo sapiens OX=9606 GN=EEF1G PE=1 SV=3 4.14 2527.5 - 910434 - - - -1.0511 - 2.101 0.481 - 503.4 1 2 0 -0.0015 13 0 0 0 1.02E+08 6.46E+07 - - - 4.4986 0.999 221125_WJC_METTL3_EV_vs_WT_F03.12710.12710.2 0.000233 22-Sep K.VAVFTENASEVK.L "sp|Q9BYD6|RM01_HUMAN,tr|H0Y8N7|H0Y8N7_HUMAN" 2 1292.6612 999 28867 12710 2 1292.663469 647.3379 "39S ribosomal protein L1, mitochondrial OS=Homo sapiens OX=9606 GN=MRPL1 PE=1 SV=2" 4.53 2527.6 - 262750 - - - 1.7305 - 1.699 0.353 - 165.6 1 2 0 0.0022 12 0 0 0 6.25E+07 0.00E+00 - - - 3.0422 0.9996 221125_WJC_METTL3_EV_vs_WT_F03.12715.12715.2 0.000376 20-Sep K.QYPLVTPNEER[166.11].N "sp|P35606|COPB2_HUMAN,tr|H0Y938|H0Y938_HUMAN,tr|A0A7I2V258|A0A7I2V258_HUMAN,tr|H0YAC7|H0YAC7_HUMAN" 4 1354.6756 45.34 28870 12715 2 1354.678037 678.3451 Coatomer subunit beta' OS=Homo sapiens OX=9606 GN=COPB2 PE=1 SV=2 4.53 2528.3 - 708778 - - - 1.762 - 1.715 0.478 - 319.4 1 2 0 0.0024 11 0 0 0 2.92E+09 6.45E+07 - - - 4.03 0.9975 221125_WJC_METTL3_EV_vs_WT_F03.12716.12716.2 0.0263 20-Nov R.LNEQASEEILK.V "sp|Q01105|SET_HUMAN,tr|A0A0C4DFV9|A0A0C4DFV9_HUMAN" 2 1272.6561 1.2 28871 12716 2 1272.651736 637.3353 Protein SET OS=Homo sapiens OX=9606 GN=SET PE=1 SV=3 4.25 2528.4 - 626691 - - - -3.4652 - 1.879 0.341 - 211.4 1 2 0 -0.0044 11 0 0 0 2.86E+07 2.38E+07 - - - 3.2645 0.9594 221125_WJC_METTL3_EV_vs_WT_F03.12718.12718.2 0.0254 16-Sep M.LQEDELLSK.M sp|Q96A49|SYAP1_HUMAN 1 1073.5605 1.32 28872 12718 2 1073.559034 537.7875 Synapse-associated protein 1 OS=Homo sapiens OX=9606 GN=SYAP1 PE=1 SV=1 4.14 2528.6 - 5.05E+06 - - - -1.3236 - 1.935 0.28 - 224.5 1 1 0 -0.0014 9 0 0 0 1.69E+08 1.28E+08 - - - 3.0184 0.9998 221125_WJC_METTL3_EV_vs_WT_F03.12728.12728.2 2.37E-05 22-Nov R.ITDVDNGYYTVK.F "sp|Q8N5A5|ZGPAT_HUMAN,tr|A0A0J9YYD9|A0A0J9YYD9_HUMAN,tr|V9GY48|V9GY48_HUMAN" 3 1386.6667 2.25 28878 12728 2 1386.668258 694.3406 Zinc finger CCCH-type with G patch domain-containing protein OS=Homo sapiens OX=9606 GN=ZGPAT PE=1 SV=3 4.21 2529.9 - 495324 - - - 1.1156 - 2.111 0.519 - 288.5 1 2 0 0.0015 12 0 0 0 2.69E+07 1.19E+07 - - - 4.8398 0.9553 221125_WJC_METTL3_EV_vs_WT_F03.12732.12732.2 0.000183 14-Sep V.WGGGLSPR.N sp|P0CZ25|D10OS_HUMAN 1 828.4242 0.65 28880 12732 2 828.423553 415.2194 Uncharacterized protein DNAH10OS OS=Homo sapiens OX=9606 GN=DNAH10OS PE=2 SV=1 9.75 2530.5 - 1.52E+06 - - - -0.8245 - 1.964 0.22 - 326.7 1 1 0 -0.0007 8 0 0 0 6.25E+07 9.65E+07 - - - 2.7014 0.9998 221125_WJC_METTL3_EV_vs_WT_F03.12733.12733.2 0.0103 20-Dec K.EVITAQDTVIK[136.11].A sp|O95347|SMC2_HUMAN 1 1223.6853 1 28881 12733 2 1223.685264 612.8499 Structural maintenance of chromosomes protein 2 OS=Homo sapiens OX=9606 GN=SMC2 PE=1 SV=2 4.37 2530.6 - 1.48E+06 - - - -0.0033 - 2.146 0.382 - 375.5 1 2 0 0 11 0 0 0 2.02E+07 2.02E+07 - - - 3.9282 0.9996 221125_WJC_METTL3_EV_vs_WT_F03.12737.12737.3 0.000735 13/44 R.LVLSTLSGR[166.11]PVK[136.11].L "sp|Q9Y2P8|RCL1_HUMAN,tr|Q5VYW8|Q5VYW8_HUMAN" 2 1286.8041 0.95 28883 12737 3 1286.80222 429.942 RNA 3'-terminal phosphate cyclase-like protein OS=Homo sapiens OX=9606 GN=RCL1 PE=1 SV=3 11 2531.1 - 2.60E+06 - - - -1.4548 - 2.024 0.333 - 121.1 1 2 0 -0.0019 12 0 0 0 3.78E+07 3.99E+07 - - - 4.2065 0.8977 221125_WJC_METTL3_EV_vs_WT_F03.12739.12739.2 3.96E-05 14-Sep V.WGGGLSPR[166.11].N sp|P0CZ25|D10OS_HUMAN 1 838.4325 0.65 28885 12739 2 838.43175 420.2235 Uncharacterized protein DNAH10OS OS=Homo sapiens OX=9606 GN=DNAH10OS PE=2 SV=1 9.75 2531.2 - 3.06E+06 - - - -0.9017 - 1.755 0.164 - 327.2 1 1 0 -0.0008 8 0 0 0 6.26E+07 9.68E+07 - - - 1.9484 0.9999 221125_WJC_METTL3_EV_vs_WT_F03.12740.12740.3 0.00698 Dec-44 R.LVLSTLSGRPVK.L "sp|Q9Y2P8|RCL1_HUMAN,tr|Q5VYW8|Q5VYW8_HUMAN" 2 1268.7816 0.95 28886 12740 3 1268.778871 423.9345 RNA 3'-terminal phosphate cyclase-like protein OS=Homo sapiens OX=9606 GN=RCL1 PE=1 SV=3 11 2531.2 - 2.43E+06 - - - -2.1682 - 2.405 0.412 - 185.6 1 2 0 -0.0028 12 0 0 0 3.78E+07 3.99E+07 - - - 5.5651 0.9998 221125_WJC_METTL3_EV_vs_WT_F03.12741.12741.2 3.27E-05 20-Nov K.VQVMVPEAETR.A "sp|Q15155|NOMO1_HUMAN,sp|Q5JPE7|NOMO2_HUMAN,sp|P69849|NOMO3_HUMAN,tr|A0A7I2V3P4|A0A7I2V3P4_HUMAN,tr|A0A7I2V6B0|A0A7I2V6B0_HUMAN,tr|A0A7I2V4D7|A0A7I2V4D7_HUMAN,tr|A0A7I2V4T6|A0A7I2V4T6_HUMAN,tr|A0A0G2JP90|A0A0G2JP90_HUMAN,tr|A0A087X117|A0A087X117_HUMAN,tr|A0A0G2JN29|A0A0G2JN29_HUMAN,tr|A0A7I2V2Z5|A0A7I2V2Z5_HUMAN,tr|H3BPS9|H3BPS9_HUMAN,tr|A0A087WW46|A0A087WW46_HUMAN,tr|J3KN36|J3KN36_HUMAN" 14 1257.6387 1.09 28887 12741 2 1257.638297 629.8266 Nodal modulator 1 OS=Homo sapiens OX=9606 GN=NOMO1 PE=1 SV=5 4.53 2531.4 - 1.04E+06 - - - -0.3379 - 2.126 0.398 - 481.8 1 2 0 -0.0004 11 0 0 0 5.54E+07 5.06E+07 - - - 4.0209 0.8143 221125_WJC_METTL3_EV_vs_WT_F03.12742.12742.2 0.538 14-Aug K.TSQIFLAK.H "sp|Q9UPN3|MACF1_HUMAN,tr|H3BQK9|H3BQK9_HUMAN,tr|A0A7P0MQR8|A0A7P0MQR8_HUMAN,tr|E9PNZ4|E9PNZ4_HUMAN,tr|H0Y390|H0Y390_HUMAN,tr|H3BPE1|H3BPE1_HUMAN,tr|A0A590UJG2|A0A590UJG2_HUMAN,tr|A0A5F9ZGX0|A0A5F9ZGX0_HUMAN" 8 906.5175 3.81 28888 12742 2 906.513285 454.266 "Microtubule-actin cross-linking factor 1, isoforms 1\2\3\5 OS=Homo sapiens OX=9606 GN=MACF1 PE=1 SV=4" 8.41 2531.5 - 752486 - - - -4.6144 - 1.468 0.018 - 211.5 1 2 0 -0.0042 8 0 0 0 2.14E+07 5.61E+06 - - - 0.3305 0.9861 221125_WJC_METTL3_EV_vs_WT_F03.12743.12743.2 0.239 16-Aug K.GGYFPENVK.A "sp|Q13045|FLII_HUMAN,tr|J3KS54|J3KS54_HUMAN" 2 1009.4869 2.53 28889 12743 2 1009.485495 505.7507 Protein flightless-1 homolog OS=Homo sapiens OX=9606 GN=FLII PE=1 SV=2 6 2531.6 - 591556 - - - -1.3878 - 1.161 0.159 - 140.6 1 2 0 -0.0014 9 0 0 0 1.49E+07 5.89E+06 - - - 0.6468 0.9999 221125_WJC_METTL3_EV_vs_WT_F03.12745.12745.2 0.0462 14-Oct K.TEDLFENR.L "sp|Q92615|LAR4B_HUMAN,tr|H0Y641|H0Y641_HUMAN,tr|H0Y4V9|H0Y4V9_HUMAN" 3 1022.4669 1.18 28890 12745 2 1022.466218 512.2407 La-related protein 4B OS=Homo sapiens OX=9606 GN=LARP4B PE=1 SV=3 4.14 2531.8 - 3.56E+07 - - - -0.6563 - 2.102 0.544 - 585.8 1 2 0 -0.0007 8 0 0 0 9.53E+08 8.07E+08 - - - 5.2993 0.9935 221125_WJC_METTL3_EV_vs_WT_F03.12747.12747.2 0.0802 16-Sep K.LAQLELENK.E sp|Q9BRV8|SIKE1_HUMAN 1 1056.5815 2.26 28891 12747 2 1056.585193 529.298 Suppressor of IKBKE 1 OS=Homo sapiens OX=9606 GN=SIKE1 PE=1 SV=1 4.53 2532 - 1.87E+06 - - - 3.4716 - 2.048 0.169 - 248.2 1 2 0 0.0037 9 0 0 0 7.39E+07 3.28E+07 - - - 2.362 0.9999 221125_WJC_METTL3_EV_vs_WT_F03.12748.12748.2 8.49E-07 22-Dec R.ITDVDNGYYTVK[136.11].F "sp|Q8N5A5|ZGPAT_HUMAN,tr|A0A0J9YYD9|A0A0J9YYD9_HUMAN,tr|V9GY48|V9GY48_HUMAN" 3 1394.6809 2.25 28892 12748 2 1394.678666 698.3477 Zinc finger CCCH-type with G patch domain-containing protein OS=Homo sapiens OX=9606 GN=ZGPAT PE=1 SV=3 4.21 2532.2 - 752127 - - - -1.6097 - 2.405 0.581 - 575.6 1 2 0 -0.0022 12 0 0 0 2.69E+07 1.19E+07 - - - 5.6405 0.9953 221125_WJC_METTL3_EV_vs_WT_F03.12749.12749.2 0.217 14-Jun K.EGIPLPTK[136.11].L "sp|Q9Y3B7|RM11_HUMAN,tr|E9PQB6|E9PQB6_HUMAN" 2 861.5051 1.19 28893 12749 2 861.504809 431.7598 "39S ribosomal protein L11, mitochondrial OS=Homo sapiens OX=9606 GN=MRPL11 PE=1 SV=1" 6.1 2532.3 - 1.66E+06 - - - -0.3598 - 1.282 0.185 - 117.1 1 2 0 -0.0003 8 0 0 0 4.94E+07 4.16E+07 - - - 1.1565 0.9923 221125_WJC_METTL3_EV_vs_WT_F03.12750.12750.3 0.0946 Nov-40 K.EGLEK[136.11]PVEIIR[166.11].H "sp|Q9UHI6|DDX20_HUMAN,tr|A0A7P0T9T8|A0A7P0T9T8_HUMAN" 2 1299.7517 4.3 28894 12750 3 1299.748591 434.2579 Probable ATP-dependent RNA helicase DDX20 OS=Homo sapiens OX=9606 GN=DDX20 PE=1 SV=2 4.79 2532.4 - 920578 - - - -2.4089 - 1.704 0.221 - 222.5 1 2 0 -0.0031 11 0 0 0 1.12E+08 2.60E+07 - - - 2.5172 0.878 221125_WJC_METTL3_EV_vs_WT_F03.12752.12752.2 0.0582 14-Jul A.GYVTHLMK.R "sp|P08708|RS17_HUMAN,tr|H3BNC9|H3BNC9_HUMAN,tr|H0YN88|H0YN88_HUMAN,tr|A0A075B716|A0A075B716_HUMAN" 4 947.4899 1.15 28895 12752 2 947.488987 474.7522 40S ribosomal protein S17 OS=Homo sapiens OX=9606 GN=RPS17 PE=1 SV=2 8.6 2532.6 - 2.72E+06 - - - -0.9351 - 1.221 0.292 - 157.2 1 1 0 -0.0009 8 0 0 0 7.47E+07 6.51E+07 - - - 1.7996 0.9997 221125_WJC_METTL3_EV_vs_WT_F03.12754.12754.2 0.00452 18-Nov R.IITEGFEAAK[136.11].E sp|P40227|TCPZ_HUMAN 1 1085.5848 0.49 28896 12754 2 1085.583681 543.7997 T-complex protein 1 subunit zeta OS=Homo sapiens OX=9606 GN=CCT6A PE=1 SV=3 4.53 2532.8 - 3.36E+06 - - - -1.0547 - 2.113 0.375 - 270.3 1 2 0 -0.0011 10 0 0 0 1.29E+08 2.65E+08 - - - 3.8986 0.9979 221125_WJC_METTL3_EV_vs_WT_F03.12755.12755.3 0.0383 Oct-36 R.GFHQEVFLGK.D "sp|Q9BRK5|CAB45_HUMAN,tr|A0A5F9UJX7|A0A5F9UJX7_HUMAN,tr|A0A5F9UP49|A0A5F9UP49_HUMAN,tr|G3V1E2|G3V1E2_HUMAN,tr|H0Y3T6|H0Y3T6_HUMAN" 5 1160.5978 1.51 28897 12755 3 1160.596311 387.8732 45 kDa calcium-binding protein OS=Homo sapiens OX=9606 GN=SDF4 PE=1 SV=1 6.75 2532.9 - 1.27E+06 - - - -1.3209 - 1.779 0.24 - 86.5 1 2 0 -0.0015 10 0 0 0 1.54E+07 1.02E+07 - - - 2.8977 0.9972 221125_WJC_METTL3_EV_vs_WT_F03.12758.12758.2 0.0201 12-Jun R.FTLYENK.D "sp|Q9GZS1|RPA49_HUMAN,tr|E7EX70|E7EX70_HUMAN" 2 913.4545 0.49 28900 12758 2 913.45252 457.7345 DNA-directed RNA polymerase I subunit RPA49 OS=Homo sapiens OX=9606 GN=POLR1E PE=1 SV=3 6 2533.3 - 881072 - - - -2.2037 - 1.389 0.298 - 105.2 1 2 0 -0.002 7 0 0 0 1.64E+07 3.39E+07 - - - 2.2825 0.9802 221125_WJC_METTL3_EV_vs_WT_F03.12761.12761.2 0.000855 16-Sep L.TNEGIQYLR.D "sp|P46783|RS10_HUMAN,tr|A0A2R8Y6L3|A0A2R8Y6L3_HUMAN,tr|F6U211|F6U211_HUMAN,tr|A0A1W2PQS6|A0A1W2PQS6_HUMAN,tr|A0A2R8YFH6|A0A2R8YFH6_HUMAN,tr|A0A2R8Y7H1|A0A2R8Y7H1_HUMAN,tr|S4R435|S4R435_HUMAN" 7 1092.5564 0.64 28901 12761 2 1092.554859 547.2855 40S ribosomal protein S10 OS=Homo sapiens OX=9606 GN=RPS10 PE=1 SV=1 5.66 2533.7 - 6.46E+06 - - - -1.3857 - 2.017 0.382 - 548 1 1 0 -0.0015 9 0 0 0 1.73E+08 2.71E+08 - - - 3.8918 0.9476 221125_WJC_METTL3_EV_vs_WT_F03.12763.12763.2 0.375 12-Aug R.FSDIQIR[166.11].R "sp|P11586|C1TC_HUMAN,tr|F5H2F4|F5H2F4_HUMAN,tr|V9GZ78|V9GZ78_HUMAN,tr|V9GYY3|V9GYY3_HUMAN,tr|A0A494C1T2|A0A494C1T2_HUMAN" 5 887.474 0.93 28903 12763 2 887.471617 444.7443 "C-1-tetrahydrofolate synthase, cytoplasmic OS=Homo sapiens OX=9606 GN=MTHFD1 PE=1 SV=4" 5.84 2533.9 - 1.17E+06 - - - -2.7268 - 1.095 0.139 - 147.2 1 2 0 -0.0024 7 0 0 0 1.87E+07 2.00E+07 - - - 0.3545 0.9803 221125_WJC_METTL3_EV_vs_WT_F03.12764.12764.2 0.769 14-Aug R.ALDIDVEK[136.11].L "sp|O00443|P3C2A_HUMAN,tr|A0A0C4DGF9|A0A0C4DGF9_HUMAN,tr|E9PPP3|E9PPP3_HUMAN" 3 909.4899 1.59 28904 12764 2 909.486595 455.7522 Phosphatidylinositol 4-phosphate 3-kinase C2 domain-containing subunit alpha OS=Homo sapiens OX=9606 GN=PIK3C2A PE=1 SV=2 4.03 2534.1 - 1.16E+06 - - - -3.5932 - 1.546 0.156 - 212 1 2 0 -0.0033 8 0 0 0 7.63E+07 4.80E+07 - - - 1.5062 0.9738 221125_WJC_METTL3_EV_vs_WT_F03.12765.12765.2 0.145 12-Jul R.FTLYENK[136.11].D "sp|Q9GZS1|RPA49_HUMAN,tr|E7EX70|E7EX70_HUMAN" 2 921.4687 0.49 28905 12765 2 921.474723 461.7416 DNA-directed RNA polymerase I subunit RPA49 OS=Homo sapiens OX=9606 GN=POLR1E PE=1 SV=3 6 2534.2 - 1.10E+06 - - - 6.5005 - 1.519 0.358 - 165.3 1 2 0 0.006 7 0 0 0 1.64E+07 3.34E+07 - - - 3.0079 0.9995 221125_WJC_METTL3_EV_vs_WT_F03.12768.12768.2 6.66E-05 20-Nov R.TALSAVDMTQR[166.11].E "sp|O95602|RPA1_HUMAN,tr|B9ZVN9|B9ZVN9_HUMAN" 2 1201.6 0.63 28906 12768 2 1201.597244 601.8073 DNA-directed RNA polymerase I subunit RPA1 OS=Homo sapiens OX=9606 GN=POLR1A PE=1 SV=2 5.5 2534.6 - 1.00E+06 - - - -2.3286 - 2.152 0.436 - 363.7 1 2 0 -0.0028 11 0 0 0 1.42E+07 2.28E+07 - - - 4.3337 0.9937 221125_WJC_METTL3_EV_vs_WT_F03.12772.12772.2 8.76E-05 20-Nov K.NLSEALGDNVK[136.11].Q sp|Q96BN2|TADA1_HUMAN 1 1166.6023 1.41 28910 12772 2 1166.598813 584.3084 Transcriptional adapter 1 OS=Homo sapiens OX=9606 GN=TADA1 PE=1 SV=1 4.37 2535 - 736650 - - - -2.9607 - 2.086 0.138 - 313.9 1 2 0 -0.0035 11 0 0 0 5.18E+07 3.67E+07 - - - 2.0482 0.9993 221125_WJC_METTL3_EV_vs_WT_F03.12775.12775.2 0.15 18-Sep R.IITEGFEAAK.E sp|P40227|TCPZ_HUMAN 1 1077.5706 0.49 28911 12775 2 1077.570683 539.7926 T-complex protein 1 subunit zeta OS=Homo sapiens OX=9606 GN=CCT6A PE=1 SV=3 4.53 2535.4 - 4.87E+06 - - - 0.0529 - 1.804 0.264 - 163.5 1 2 0 0.0001 10 0 0 0 1.29E+08 2.66E+08 - - - 2.6378 0.9966 221125_WJC_METTL3_EV_vs_WT_F03.12776.12776.2 0.437 14-Aug R.ALDIDVEK.L "sp|O00443|P3C2A_HUMAN,tr|A0A0C4DGF9|A0A0C4DGF9_HUMAN,tr|E9PPP3|E9PPP3_HUMAN" 3 901.4757 1.5 28912 12776 2 901.474689 451.7451 Phosphatidylinositol 4-phosphate 3-kinase C2 domain-containing subunit alpha OS=Homo sapiens OX=9606 GN=PIK3C2A PE=1 SV=2 4.03 2535.5 - 2.57E+06 - - - -1.0805 - 1.548 0.161 - 192.8 1 2 0 -0.001 8 0 0 0 9.33E+07 6.23E+07 - - - 1.5477 0.9941 221125_WJC_METTL3_EV_vs_WT_F03.12777.12777.2 0.211 12-Jun K.SSFFSDR[166.11].G "sp|O00571|DDX3X_HUMAN,tr|A0A2R8YFR4|A0A2R8YFR4_HUMAN,tr|A0A2R8YCW1|A0A2R8YCW1_HUMAN,tr|A0A2R8YDH3|A0A2R8YDH3_HUMAN,tr|A0A2R8Y645|A0A2R8Y645_HUMAN,tr|A0A2R8YF78|A0A2R8YF78_HUMAN,tr|A0A2R8YCU0|A0A2R8YCU0_HUMAN,tr|A0A0D9SFB3|A0A0D9SFB3_HUMAN,tr|A0A2R8YFS5|A0A2R8YFS5_HUMAN,tr|A0A0D9SF53|A0A0D9SF53_HUMAN,tr|A0A2R8Y650|A0A2R8Y650_HUMAN,tr|A0A087WX09|A0A087WX09_HUMAN,tr|A0A2R8Y5G6|A0A2R8Y5G6_HUMAN,tr|A0A0D9SG12|A0A0D9SG12_HUMAN,tr|F6S8Q4|F6S8Q4_HUMAN,tr|A0A2U3TZJ9|A0A2U3TZJ9_HUMAN,tr|A0A2R8Y4A4|A0A2R8Y4A4_HUMAN,tr|A0A2R8YF89|A0A2R8YF89_HUMAN" 18 854.3798 1.09 28913 12777 2 854.378854 428.1972 ATP-dependent RNA helicase DDX3X OS=Homo sapiens OX=9606 GN=DDX3X PE=1 SV=3 5.55 2535.6 - 3.44E+06 - - - -1.1096 - 1.207 0.204 - 154.8 1 2 0 -0.0009 7 0 0 0 3.23E+08 2.96E+08 - - - 1.1436 0.9997 221125_WJC_METTL3_EV_vs_WT_F03.12778.12778.2 0.01 15/24 K.IAAEIAQAEEQAR.K "sp|Q969G3|SMCE1_HUMAN,tr|A0A2R8Y855|A0A2R8Y855_HUMAN,tr|A0A2R8YES3|A0A2R8YES3_HUMAN,tr|A0A2U3TZQ7|A0A2U3TZQ7_HUMAN,tr|A0A2R8Y7U4|A0A2R8Y7U4_HUMAN,tr|B4DGM3|B4DGM3_HUMAN,tr|J3QKS7|J3QKS7_HUMAN,tr|A0A2R8Y4T4|A0A2R8Y4T4_HUMAN,tr|A0A2R8Y7I9|A0A2R8Y7I9_HUMAN,tr|A0A2R8Y765|A0A2R8Y765_HUMAN" 10 1398.7103 1.63 28914 12778 2 1398.707377 700.3624 SWI\SNF-related matrix-associated actin-dependent regulator of chromatin subfamily E member 1 OS=Homo sapiens OX=9606 GN=SMARCE1 PE=1 SV=2 4.25 2535.7 - 1.04E+06 - - - -2.0948 - 2.665 0.416 - 655.4 1 2 0 -0.0029 13 0 0 0 2.53E+07 1.55E+07 - - - 4.6284 0.9998 221125_WJC_METTL3_EV_vs_WT_F03.12779.12779.3 0.00437 Oct-44 R.AQPSVSLGAAYR.A sp|Q96PK6|RBM14_HUMAN 1 1218.6357 0.92 28915 12779 3 1218.633462 407.2192 RNA-binding protein 14 OS=Homo sapiens OX=9606 GN=RBM14 PE=1 SV=2 8.79 2535.8 - 765634 - - - -1.825 - 2.299 0.357 - 119.6 1 2 0 -0.0022 12 0 0 0 2.11E+07 2.29E+07 - - - 4.8271 0.9996 221125_WJC_METTL3_EV_vs_WT_F03.12785.12785.2 0.00154 16-Oct K.NC[160.03]IDITGVR[166.11].L "sp|Q12907|LMAN2_HUMAN,tr|D6RBV2|D6RBV2_HUMAN,tr|D6RDX1|D6RDX1_HUMAN,tr|D6RIU4|D6RIU4_HUMAN" 4 1056.5261 1.42 28919 12785 2 1056.526837 529.2704 Vesicular integral-membrane protein VIP36 OS=Homo sapiens OX=9606 GN=LMAN2 PE=1 SV=1 5.83 2536.5 - 708568 - - - 0.6512 - 1.791 0.347 - 348.8 1 2 0 0.0007 9 0 0 0 2.05E+07 1.44E+07 - - - 3.2897 0.9582 221125_WJC_METTL3_EV_vs_WT_F03.12786.12786.3 0.263 Sep-32 R.LQQHLLEIR.G sp|A6NKD9|CC85C_HUMAN 1 1148.6666 3.36 28920 12786 3 1148.664308 383.8961 Coiled-coil domain-containing protein 85C OS=Homo sapiens OX=9606 GN=CCDC85C PE=1 SV=1 6.75 2536.6 - 571449 - - - -1.9884 - 1.404 0.155 - 79.6 1 2 0 -0.0023 9 0 0 0 5.49E+07 1.63E+07 - - - 1.2901 0.9988 221125_WJC_METTL3_EV_vs_WT_F03.12789.12789.2 0.00893 12-Aug R.NQQIFLR[166.11].D "sp|P62993|GRB2_HUMAN,tr|J3QLF6|J3QLF6_HUMAN" 2 927.5166 1.07 28921 12789 2 927.514698 464.7656 Growth factor receptor-bound protein 2 OS=Homo sapiens OX=9606 GN=GRB2 PE=1 SV=1 9.75 2537 - 1.43E+06 - - - -2.0183 - 1.628 0.314 - 422.9 1 2 0 -0.0019 7 0 0 0 4.30E+07 4.03E+07 - - - 2.9038 0.9994 221125_WJC_METTL3_EV_vs_WT_F03.12791.12791.2 0.587 13/20 K.NLSEALGDNVK.Q sp|Q96BN2|TADA1_HUMAN 1 1158.5881 1.31 28923 12791 2 1158.585443 580.3013 Transcriptional adapter 1 OS=Homo sapiens OX=9606 GN=TADA1 PE=1 SV=1 4.37 2537.2 - 1.73E+06 - - - -2.2648 - 2.339 0.358 - 485.6 1 2 0 -0.0026 11 0 0 0 4.69E+07 3.58E+07 - - - 3.9831 0.9501 221125_WJC_METTL3_EV_vs_WT_F03.12793.12793.2 0.0929 12-Jun K.FSEQVFK[136.11].V "sp|O75955|FLOT1_HUMAN,tr|A2AB10|A2AB10_HUMAN,tr|A0A140T910|A0A140T910_HUMAN,tr|A2AB09|A2AB09_HUMAN,tr|A2AB11|A2AB11_HUMAN,tr|A0A140T9C3|A0A140T9C3_HUMAN,tr|A0A140T9R1|A0A140T9R1_HUMAN,tr|A0A140T957|A0A140T957_HUMAN,tr|A0A140T9B1|A0A140T9B1_HUMAN,tr|A0A140T959|A0A140T959_HUMAN,tr|A2AB12|A2AB12_HUMAN,tr|A0A0G2JJQ6|A0A0G2JJQ6_HUMAN,tr|A0A140T9X0|A0A140T9X0_HUMAN,tr|A2AB13|A2AB13_HUMAN" 14 891.4582 1.6 28925 12793 2 891.455514 446.7364 Flotillin-1 OS=Homo sapiens OX=9606 GN=FLOT1 PE=1 SV=3 6 2537.5 - 1.02E+06 - - - -2.9783 - 1.271 0.096 - 81 1 2 0 -0.0027 7 0 0 0 3.48E+07 2.17E+07 - - - 0.5091 0.9876 221125_WJC_METTL3_EV_vs_WT_F03.12797.12797.2 0.107 12-Jun K.SSFFSDR.G "sp|O00571|DDX3X_HUMAN,tr|A0A2R8YFR4|A0A2R8YFR4_HUMAN,tr|A0A2R8YCW1|A0A2R8YCW1_HUMAN,tr|A0A2R8YDH3|A0A2R8YDH3_HUMAN,tr|A0A2R8Y645|A0A2R8Y645_HUMAN,tr|A0A2R8YF78|A0A2R8YF78_HUMAN,tr|A0A2R8YCU0|A0A2R8YCU0_HUMAN,tr|A0A0D9SFB3|A0A0D9SFB3_HUMAN,tr|A0A2R8YFS5|A0A2R8YFS5_HUMAN,tr|A0A0D9SF53|A0A0D9SF53_HUMAN,tr|A0A2R8Y650|A0A2R8Y650_HUMAN,tr|A0A087WX09|A0A087WX09_HUMAN,tr|A0A2R8Y5G6|A0A2R8Y5G6_HUMAN,tr|A0A0D9SG12|A0A0D9SG12_HUMAN,tr|F6S8Q4|F6S8Q4_HUMAN,tr|A0A2U3TZJ9|A0A2U3TZJ9_HUMAN,tr|A0A2R8Y4A4|A0A2R8Y4A4_HUMAN,tr|A0A2R8YF89|A0A2R8YF89_HUMAN" 18 844.3715 1.09 28927 12797 2 844.369558 423.193 ATP-dependent RNA helicase DDX3X OS=Homo sapiens OX=9606 GN=DDX3X PE=1 SV=3 5.55 2538 - 9.93E+06 - - - -2.3378 - 1.229 0.2 - 157 1 2 0 -0.002 7 0 0 0 3.23E+08 2.96E+08 - - - 1.1709 0.9995 221125_WJC_METTL3_EV_vs_WT_F03.12798.12798.2 0.000184 16-Aug R.ENVNLAQIR[166.11].T "sp|P48444|COPD_HUMAN,tr|B0YIW6|B0YIW6_HUMAN,tr|Q6P1Q5|Q6P1Q5_HUMAN" 3 1065.5806 1.18 28928 12798 2 1065.579571 533.7976 Coatomer subunit delta OS=Homo sapiens OX=9606 GN=ARCN1 PE=1 SV=1 6.1 2538.1 - 1.50E+06 - - - -0.991 - 1.811 0.327 - 310 1 2 0 -0.0011 9 0 0 0 2.91E+07 2.48E+07 - - - 3.174 0.9991 221125_WJC_METTL3_EV_vs_WT_F03.12799.12799.2 0.00131 12-Sep R.NQQIFLR.D "sp|P62993|GRB2_HUMAN,tr|J3QLF6|J3QLF6_HUMAN" 2 917.5083 0.95 28929 12799 2 917.505937 459.7614 Growth factor receptor-bound protein 2 OS=Homo sapiens OX=9606 GN=GRB2 PE=1 SV=1 9.75 2538.2 - 1.54E+06 - - - -2.5755 - 1.768 0.377 - 491.6 1 2 0 -0.0024 7 0 0 0 4.39E+07 4.64E+07 - - - 3.6304 1 221125_WJC_METTL3_EV_vs_WT_F03.12800.12800.2 9.47E-07 15/26 R.SLYASSPGGVYATR.S "sp|P08670|VIME_HUMAN,tr|B0YJC4|B0YJC4_HUMAN,tr|A0A1B0GVG8|A0A1B0GVG8_HUMAN,tr|A0A1B0GTT5|A0A1B0GTT5_HUMAN" 4 1427.7045 -1 28930 12800 2 1427.704106 714.8595 Vimentin OS=Homo sapiens OX=9606 GN=VIM PE=1 SV=4 8.31 2538.4 - 899556 - - - -0.2718 - 2.671 0.612 - 631.3 1 2 0 -0.0004 14 0 0 0 0.00E+00 0.00E+00 - - - 6.0265 0.995 221125_WJC_METTL3_EV_vs_WT_F03.12803.12803.3 0.000248 Dec-36 R.LKYENELALR.Q "sp|P19012|K1C15_HUMAN,sp|P13646|K1C13_HUMAN,tr|K7EMD9|K7EMD9_HUMAN,tr|K7ERE3|K7ERE3_HUMAN" 4 1247.6874 91.73 28931 12803 3 1247.685894 416.9031 "Keratin, type I cytoskeletal 15 OS=Homo sapiens OX=9606 GN=KRT15 PE=1 SV=3" 6.14 2538.7 - 1.99E+06 - - - -1.1966 - 2.15 0.228 - 196.4 1 2 1 -0.0015 10 0 0 0 1.52E+08 1.66E+06 - - - 3.3171 0.9938 221125_WJC_METTL3_EV_vs_WT_F03.12804.12804.2 0.00365 22-Oct R.LSEIDVSSEGVK[136.11].G "sp|Q96C19|EFHD2_HUMAN,tr|H0Y4Y4|H0Y4Y4_HUMAN" 2 1269.6544 0.99 28932 12804 2 1269.647496 635.8345 EF-hand domain-containing protein D2 OS=Homo sapiens OX=9606 GN=EFHD2 PE=1 SV=1 4.14 2538.8 - 1.65E+06 - - - -5.4078 - 2.04 0.395 - 288.3 1 2 0 -0.0069 12 0 0 0 2.48E+07 2.49E+07 - - - 3.8322 0.9963 221125_WJC_METTL3_EV_vs_WT_F03.12805.12805.3 0.18 Oct-36 K.VLSNR[166.11]PIMFR[166.11].G "sp|Q13283|G3BP1_HUMAN,tr|A0A7I2YQF2|A0A7I2YQF2_HUMAN,tr|A0A7I2V5M7|A0A7I2V5M7_HUMAN,tr|A0A7I2YQH0|A0A7I2YQH0_HUMAN" 4 1251.7025 1.05 28933 12805 3 1251.700512 418.2414 Ras GTPase-activating protein-binding protein 1 OS=Homo sapiens OX=9606 GN=G3BP1 PE=1 SV=1 12 2538.9 - 2.32E+06 - - - -1.5779 - 1.692 0.229 - 173.7 1 2 0 -0.002 10 0 0 0 6.90E+08 6.60E+08 - - - 2.6285 0.9998 221125_WJC_METTL3_EV_vs_WT_F03.12806.12806.2 0.011 13/22 R.LSEIDVSSEGVK.G "sp|Q96C19|EFHD2_HUMAN,tr|H0Y4Y4|H0Y4Y4_HUMAN" 2 1261.6402 1.06 28934 12806 2 1261.63864 631.8274 EF-hand domain-containing protein D2 OS=Homo sapiens OX=9606 GN=EFHD2 PE=1 SV=1 4.14 2539 - 1.73E+06 - - - -1.2064 - 2.626 0.413 - 843.6 1 2 0 -0.0015 12 0 0 0 2.48E+07 2.34E+07 - - - 4.6312 0.9946 221125_WJC_METTL3_EV_vs_WT_F03.12809.12809.3 0.214 Nov-36 K.VLSNRPIMFR.G "sp|Q13283|G3BP1_HUMAN,tr|A0A7I2YQF2|A0A7I2YQF2_HUMAN,tr|A0A7I2V5M7|A0A7I2V5M7_HUMAN,tr|A0A7I2YQH0|A0A7I2YQH0_HUMAN" 4 1231.6859 1.01 28937 12809 3 1231.688629 411.5693 Ras GTPase-activating protein-binding protein 1 OS=Homo sapiens OX=9606 GN=G3BP1 PE=1 SV=1 12 2539.4 - 911560 - - - 2.1775 - 1.729 0.228 - 205.9 1 2 0 0.0027 10 0 0 0 6.90E+08 6.84E+08 - - - 2.6803 0.9354 221125_WJC_METTL3_EV_vs_WT_F03.12813.12813.2 4.31E-06 18-Sep K.AEGFVDALHR.V "sp|Q96I24|FUBP3_HUMAN,tr|A0A494C1K6|A0A494C1K6_HUMAN" 2 1113.5567 22.55 28939 12813 2 1114.561466 557.7856 Far upstream element-binding protein 3 OS=Homo sapiens OX=9606 GN=FUBP3 PE=1 SV=2 5.32 2539.9 - 5.30E+06 - - - 902.2971 - 2.107 0.199 - 211.5 1 2 0 1.0048 10 0 0 0 3.08E+07 1.37E+06 - - - 2.2756 0.9996 221125_WJC_METTL3_EV_vs_WT_F03.12814.12814.2 1.17 14-Sep K.IGIEIIK[136.11]R[166.11].T "sp|P10809|CH60_HUMAN,tr|A0A7I2V2X6|A0A7I2V2X6_HUMAN,tr|A0A7I2YQK6|A0A7I2YQK6_HUMAN,tr|A0A7I2V599|A0A7I2V599_HUMAN" 4 958.6294 1.22 28940 12814 2 958.629258 480.322 "60 kDa heat shock protein, mitochondrial OS=Homo sapiens OX=9606 GN=HSPD1 PE=1 SV=2" 8.75 2540 - 4.92E+06 - - - -0.1711 - 2.02 0.279 - 231.3 1 2 0 -0.0002 8 0 0 0 2.05E+09 1.68E+09 - - - 3.2222 0.9996 221125_WJC_METTL3_EV_vs_WT_F03.12816.12816.2 0.819 14-Sep K.IGIEIIKR.T "sp|P10809|CH60_HUMAN,tr|A0A7I2V2X6|A0A7I2V2X6_HUMAN,tr|A0A7I2YQK6|A0A7I2YQK6_HUMAN,tr|A0A7I2V599|A0A7I2V599_HUMAN" 4 940.607 1.22 28942 12816 2 940.606406 471.3108 "60 kDa heat shock protein, mitochondrial OS=Homo sapiens OX=9606 GN=HSPD1 PE=1 SV=2" 8.75 2540.1 - 3.37E+06 - - - -0.5805 - 2.068 0.271 - 249.3 1 2 0 -0.0005 8 0 0 0 2.05E+09 1.68E+09 - - - 3.2338 0.9989 221125_WJC_METTL3_EV_vs_WT_F03.12817.12817.2 0.0266 18-Dec R.ELEAELEDER[166.11].K sp|P35580|MYH10_HUMAN 1 1241.5651 0.57 28943 12817 2 1241.561234 621.7898 Myosin-10 OS=Homo sapiens OX=9606 GN=MYH10 PE=1 SV=3 3.83 2540.1 - 2.13E+06 - - - -3.1106 - 2.249 0.347 - 709.7 1 2 0 -0.0039 10 0 0 0 2.05E+07 3.57E+07 - - - 3.865 0.9987 221125_WJC_METTL3_EV_vs_WT_F03.12818.12818.2 0.0115 18-Aug R.YVMTTTTLER[166.11].T "sp|P05198|IF2A_HUMAN,tr|H0YJS4|H0YJS4_HUMAN,tr|G3V4T5|G3V4T5_HUMAN" 3 1223.6095 0.92 28944 12818 2 1223.609614 612.812 Eukaryotic translation initiation factor 2 subunit 1 OS=Homo sapiens OX=9606 GN=EIF2S1 PE=1 SV=3 6 2540.2 - 3.17E+06 - - - 0.0572 - 1.328 0.31 - 214.9 1 2 0 0.0001 10 0 0 0 2.42E+07 2.62E+07 - - - 2.1225 0.9723 221125_WJC_METTL3_EV_vs_WT_F03.12819.12819.2 0.000345 16-Nov L.R[166.11]LPLQDVYK[136.11].L "sp|Q05639|EF1A2_HUMAN,sp|P68104|EF1A1_HUMAN,sp|Q5VTE0|EF1A3_HUMAN,tr|A0A7I2V659|A0A7I2V659_HUMAN,tr|A0A7I2V3H3|A0A7I2V3H3_HUMAN,tr|A0A2U3TZH3|A0A2U3TZH3_HUMAN,tr|A0A7I2V5N4|A0A7I2V5N4_HUMAN,tr|A0A087WVQ9|A0A087WVQ9_HUMAN,tr|A0A087WV01|A0A087WV01_HUMAN" 9 1148.6673 0.19 28945 12819 2 1148.666517 575.3409 Elongation factor 1-alpha 2 OS=Homo sapiens OX=9606 GN=EEF1A2 PE=1 SV=1 8.59 2540.3 - 1.42E+06 - - - -0.6503 - 2.246 0.238 - 468.4 1 1 0 -0.0007 9 0 0 0 3.91E+06 2.10E+07 - - - 3.1396 0.9989 221125_WJC_METTL3_EV_vs_WT_F03.12821.12821.2 0.147 16-Jul R.TPLPTLNER[166.11].D "sp|Q7KZI7|MARK2_HUMAN,tr|A0A0A0MRU9|A0A0A0MRU9_HUMAN,tr|E7ETY4|E7ETY4_HUMAN,tr|A0A7I2YQR3|A0A7I2YQR3_HUMAN,tr|E9PC69|E9PC69_HUMAN" 5 1049.5745 0.88 28947 12821 2 1049.574828 525.7945 Serine\threonine-protein kinase MARK2 OS=Homo sapiens OX=9606 GN=MARK2 PE=1 SV=2 5.66 2540.5 - 1.11E+06 - - - 0.3325 - 1.641 0.256 - 155.6 1 2 0 0.0003 9 0 0 0 2.33E+07 2.66E+07 - - - 2.3647 0.9999 221125_WJC_METTL3_EV_vs_WT_F03.12822.12822.2 1.80E-07 16/26 K.YLNEAAGVAAEEAR.N sp|Q8IZH2|XRN1_HUMAN 1 1462.7052 1.63 28948 12822 2 1462.706608 732.3599 5'-3' exoribonuclease 1 OS=Homo sapiens OX=9606 GN=XRN1 PE=1 SV=1 4.25 2540.7 - 1.07E+06 - - - 0.9476 - 2.993 0.494 - 930.3 1 2 0 0.0014 14 0 0 0 5.35E+07 3.28E+07 - - - 5.4403 1 221125_WJC_METTL3_EV_vs_WT_F03.12823.12823.2 1.05E-06 16/26 K.YLNEAAGVAAEEAR[166.11].N sp|Q8IZH2|XRN1_HUMAN 1 1472.7135 1.63 28949 12823 2 1472.711353 737.364 5'-3' exoribonuclease 1 OS=Homo sapiens OX=9606 GN=XRN1 PE=1 SV=1 4.25 2540.8 - 1.04E+06 - - - -1.4524 - 3.031 0.542 - 723.2 1 2 0 -0.0021 14 0 0 0 5.35E+07 3.28E+07 - - - 5.8263 0.9999 221125_WJC_METTL3_EV_vs_WT_F03.12824.12824.2 8.37E-06 13/26 K.TYGGC[160.03]EGPDAMYVK.L "sp|Q15369|ELOC_HUMAN,tr|R4GMY8|R4GMY8_HUMAN,tr|E5RHG8|E5RHG8_HUMAN" 3 1546.6432 0.97 28950 12824 2 1546.641584 774.3289 Elongin-C OS=Homo sapiens OX=9606 GN=ELOC PE=1 SV=1 4.37 2540.9 - 717161 - - - -1.0552 - 1.933 0.622 - 357.3 1 2 0 -0.0016 14 0 0 0 2.28E+07 2.35E+07 - - - 5.2885 0.9999 221125_WJC_METTL3_EV_vs_WT_F03.12825.12825.2 0.00031 26-Sep R.ILC[160.03]DVPC[160.03]SGDGTMR[166.11].K sp|Q08J23|NSUN2_HUMAN 1 1589.6876 0.71 28951 12825 2 1589.68655 795.8511 RNA cytosine C(5)-methyltransferase NSUN2 OS=Homo sapiens OX=9606 GN=NSUN2 PE=1 SV=2 4.21 2541.1 - 492530 - - - -0.6316 - 1.878 0.594 - 108.2 1 2 0 -0.001 14 0 0 0 6.34E+06 8.87E+06 - - - 5.0094 0.9999 221125_WJC_METTL3_EV_vs_WT_F03.12826.12826.2 5.97E-06 13/26 R.ILC[160.03]DVPC[160.03]SGDGTMR.K sp|Q08J23|NSUN2_HUMAN 1 1579.6793 0.71 28952 12826 2 1579.678901 790.8469 RNA cytosine C(5)-methyltransferase NSUN2 OS=Homo sapiens OX=9606 GN=NSUN2 PE=1 SV=2 4.21 2541.2 - 272981 - - - -0.2425 - 2.253 0.62 - 373.7 1 2 0 -0.0004 14 0 0 0 6.34E+06 8.87E+06 - - - 5.6585 0.9995 221125_WJC_METTL3_EV_vs_WT_F03.12830.12830.2 0.0014 16-Aug R.SSPQLDPLR.K sp|Q8ND56|LS14A_HUMAN 1 1011.5349 1.04 28954 12830 2 1011.533739 506.7747 Protein LSM14 homolog A OS=Homo sapiens OX=9606 GN=LSM14A PE=1 SV=3 5.55 2541.6 - 3.88E+06 - - - -1.1567 - 1.549 0.4 - 269.5 1 2 0 -0.0012 9 0 0 0 3.76E+08 3.62E+08 - - - 3.2611 0.9879 221125_WJC_METTL3_EV_vs_WT_F03.12831.12831.2 0.224 16-Aug R.SSPQLDPLR[166.11].K sp|Q8ND56|LS14A_HUMAN 1 1021.5432 1.06 28955 12831 2 1021.542949 511.7789 Protein LSM14 homolog A OS=Homo sapiens OX=9606 GN=LSM14A PE=1 SV=3 5.55 2541.7 - 5.10E+06 - - - -0.2251 - 1.504 0.036 - 280.2 1 2 0 -0.0002 9 0 0 0 3.73E+08 3.53E+08 - - - 0.4876 0.9902 221125_WJC_METTL3_EV_vs_WT_F03.12834.12834.2 0.844 16-Aug R.ISVFR[166.11]PGLR[166.11].D "sp|Q04837|SSBP_HUMAN,tr|C9K0U8|C9K0U8_HUMAN,tr|A0A0G2JLD8|A0A0G2JLD8_HUMAN,tr|E7EUY5|E7EUY5_HUMAN" 4 1063.6405 1.5 28958 12834 2 1063.64031 532.8275 "Single-stranded DNA-binding protein, mitochondrial OS=Homo sapiens OX=9606 GN=SSBP1 PE=1 SV=1" 12 2541.9 - 2.49E+06 - - - -0.2153 - 1.449 0.112 - 100.5 5 2 0 -0.0002 9 0 0 0 1.16E+08 7.75E+07 - - - 0.6289 0.9826 221125_WJC_METTL3_EV_vs_WT_F03.12835.12835.2 0.00347 14-Aug E.GFVDALHR.V "sp|Q96I24|FUBP3_HUMAN,tr|A0A494C1K6|A0A494C1K6_HUMAN" 2 913.477 1.33 28959 12835 2 913.476219 457.7458 Far upstream element-binding protein 3 OS=Homo sapiens OX=9606 GN=FUBP3 PE=1 SV=2 6.74 2541.9 - 2.47E+06 - - - -0.855 - 1.684 0.424 - 320.4 1 1 0 -0.0008 8 0 0 0 4.28E+07 3.22E+07 - - - 3.7442 0.8965 221125_WJC_METTL3_EV_vs_WT_F03.12836.12836.2 1.04E-05 18-Dec E.STGVFTTMEK.A "sp|P04406|G3P_HUMAN,tr|E7EUT5|E7EUT5_HUMAN" 2 1099.522 14.8 28960 12836 2 1099.516802 550.7683 Glyceraldehyde-3-phosphate dehydrogenase OS=Homo sapiens OX=9606 GN=GAPDH PE=1 SV=3 5.72 2542 - 2.04E+06 - - - -4.692 - 2.316 0.463 - 746 1 1 0 -0.0052 10 0 0 0 5.25E+07 3.55E+06 - - - 4.8034 1 221125_WJC_METTL3_EV_vs_WT_F03.12837.12837.2 2.09E-10 13/26 K.TYGGC[160.03]EGPDAMYVK[136.11].L "sp|Q15369|ELOC_HUMAN,tr|R4GMY8|R4GMY8_HUMAN,tr|E5RHG8|E5RHG8_HUMAN" 3 1554.6574 0.97 28961 12837 2 1554.657425 778.336 Elongin-C OS=Homo sapiens OX=9606 GN=ELOC PE=1 SV=1 4.37 2542.1 - 1.08E+06 - - - 0.0058 - 2.49 0.675 - 302.1 1 2 0 0 14 0 0 0 2.28E+07 2.35E+07 - - - 6.3159 0.9999 221125_WJC_METTL3_EV_vs_WT_F03.12838.12838.3 1.62E-05 15/40 K.LGVLHPDVITK[136.11].F sp|Q9NSD9|SYFB_HUMAN 1 1198.7165 0.59 28962 12838 3 1198.715209 400.5794 Phenylalanine--tRNA ligase beta subunit OS=Homo sapiens OX=9606 GN=FARSB PE=1 SV=3 6.74 2542.3 - 759596 - - - -1.0845 - 2.449 0.417 - 197.8 1 2 0 -0.0013 11 0 0 0 6.50E+06 1.11E+07 - - - 5.7333 0.9952 221125_WJC_METTL3_EV_vs_WT_F03.12839.12839.2 0.0328 14-Jul K.LADISLGK.E sp|Q02413|DSG1_HUMAN 1 815.4753 6.4 28963 12839 2 815.474871 408.7449 Desmoglein-1 OS=Homo sapiens OX=9606 GN=DSG1 PE=1 SV=2 5.84 2542.4 - 690206 - - - -0.4881 - 1.651 0.081 - 109.3 1 2 0 -0.0004 8 0 0 0 7.49E+06 1.17E+06 - - - 1.1513 0.9998 221125_WJC_METTL3_EV_vs_WT_F03.12840.12840.2 0.00134 20-Nov K.VLNSNPPPIIK[136.11].Y sp|Q9BTX1|NDC1_HUMAN 1 1198.7165 2.13 28964 12840 2 1198.71564 600.3655 Nucleoporin NDC1 OS=Homo sapiens OX=9606 GN=NDC1 PE=1 SV=2 8.72 2542.5 - 503902 - - - -0.7249 - 2.078 0.406 - 366.9 1 2 0 -0.0009 11 0 0 0 1.55E+07 7.26E+06 - - - 4.0181 1 221125_WJC_METTL3_EV_vs_WT_F03.12845.12845.2 3.96E-07 15/26 R.SLYASSPGGVYATR[166.11].S "sp|P08670|VIME_HUMAN,tr|B0YJC4|B0YJC4_HUMAN,tr|A0A1B0GVG8|A0A1B0GVG8_HUMAN,tr|A0A1B0GTT5|A0A1B0GTT5_HUMAN" 4 1437.7128 1.89 28967 12845 2 1437.721173 719.8637 Vimentin OS=Homo sapiens OX=9606 GN=VIM PE=1 SV=4 8.31 2543.2 - 5.07E+07 - - - 5.8489 - 2.721 0.591 - 670.1 1 2 0 0.0084 14 0 0 0 9.29E+09 4.93E+09 - - - 5.9154 0.9998 221125_WJC_METTL3_EV_vs_WT_F03.12847.12847.2 0.139 14-Sep R.NGYGFINR[166.11].N "sp|Q9Y2T7|YBOX2_HUMAN,sp|P67809|YBOX1_HUMAN,sp|P16989|YBOX3_HUMAN,tr|C9J5V9|C9J5V9_HUMAN" 4 949.4645 1.03 28969 12847 2 949.464211 475.7395 Y-box-binding protein 2 OS=Homo sapiens OX=9606 GN=YBX2 PE=1 SV=2 8.75 2543.3 - 6.48E+06 - - - -0.3412 - 2.074 0.411 - 314.9 1 2 0 -0.0003 8 0 0 0 9.81E+08 9.49E+08 - - - 4.2766 0.9995 221125_WJC_METTL3_EV_vs_WT_F03.12850.12850.2 0.00382 20-Nov K.VLNSNPPPIIK.Y sp|Q9BTX1|NDC1_HUMAN 1 1190.7023 2.22 28972 12850 2 1190.700827 596.3584 Nucleoporin NDC1 OS=Homo sapiens OX=9606 GN=NDC1 PE=1 SV=2 8.72 2543.5 - 985823 - - - -1.2446 - 1.723 0.37 - 320.6 1 2 0 -0.0015 11 0 0 0 1.38E+07 6.23E+06 - - - 3.2452 0.9974 221125_WJC_METTL3_EV_vs_WT_F03.12853.12853.2 0.0682 16-Sep R.TTIFSPEGR[166.11].L "sp|P25789|PSA4_HUMAN,tr|H0YMI6|H0YMI6_HUMAN,tr|H0YLS6|H0YLS6_HUMAN,tr|H0YMA1|H0YMA1_HUMAN,tr|H0YLC2|H0YLC2_HUMAN,tr|H0YL69|H0YL69_HUMAN,tr|H0YMZ1|H0YMZ1_HUMAN" 7 1016.5166 0.79 28973 12853 2 1016.51383 509.2656 Proteasome subunit alpha type-4 OS=Homo sapiens OX=9606 GN=PSMA4 PE=1 SV=1 5.66 2543.9 - 5.89E+06 - - - -2.7545 - 1.709 0.287 - 291.7 1 2 0 -0.0028 9 0 0 0 1.46E+08 1.85E+08 - - - 2.7103 0.9898 221125_WJC_METTL3_EV_vs_WT_F03.12854.12854.3 0.0246 14/40 K.LVDPER[166.11]DMSLR[166.11].L "sp|Q14444|CAPR1_HUMAN,tr|G3V153|G3V153_HUMAN" 2 1349.6876 1.43 28974 12854 3 1349.685117 450.9032 Caprin-1 OS=Homo sapiens OX=9606 GN=CAPRIN1 PE=1 SV=2 4.56 2544 - 2.11E+06 - - - -1.8582 - 1.959 0.237 - 224.4 1 2 1 -0.0025 11 0 0 0 2.20E+08 1.54E+08 - - - 3.0919 0.986 221125_WJC_METTL3_EV_vs_WT_F03.12856.12856.2 1.43 18-Oct K.VLSNR[166.11]PIMFR[166.11].G "sp|Q13283|G3BP1_HUMAN,tr|A0A7I2YQF2|A0A7I2YQF2_HUMAN,tr|A0A7I2V5M7|A0A7I2V5M7_HUMAN,tr|A0A7I2YQH0|A0A7I2YQH0_HUMAN" 4 1251.7025 0.71 28976 12856 2 1251.702078 626.8585 Ras GTPase-activating protein-binding protein 1 OS=Homo sapiens OX=9606 GN=G3BP1 PE=1 SV=1 12 2544.1 - 1.73E+06 - - - -0.3268 - 1.338 0.073 - 146.5 1 2 0 -0.0004 10 0 0 0 6.96E+07 9.81E+07 - - - 0.3928 0.999 221125_WJC_METTL3_EV_vs_WT_F03.12857.12857.2 0.0191 20-Aug R.LGLPGDEVDNK.V sp|P78527|PRKDC_HUMAN 1 1155.5772 0.42 28977 12857 2 1155.57733 578.7959 DNA-dependent protein kinase catalytic subunit OS=Homo sapiens OX=9606 GN=PRKDC PE=1 SV=3 4.03 2544.2 - 1.66E+06 - - - 0.1402 - 1.621 0.276 - 130.1 1 2 0 0.0002 11 0 0 0 6.67E+07 1.59E+08 - - - 2.3862 0.9756 221125_WJC_METTL3_EV_vs_WT_F03.12858.12858.2 0.424 14-Aug K.GIDLTQVK[136.11].G "sp|P10515|ODP2_HUMAN,tr|A0A7P0TBE2|A0A7P0TBE2_HUMAN,tr|A0A7P0Z4G4|A0A7P0Z4G4_HUMAN,tr|A0A7P0TAX2|A0A7P0TAX2_HUMAN,tr|A0A7P0TBK2|A0A7P0TBK2_HUMAN,tr|E9PEJ4|E9PEJ4_HUMAN,tr|A0A7P0TAG1|A0A7P0TAG1_HUMAN,tr|A0A7P0TA47|A0A7P0TA47_HUMAN,tr|A0A7P0T997|A0A7P0T997_HUMAN,tr|H0YDD4|H0YDD4_HUMAN" 10 880.5109 0.93 28978 12858 2 880.509324 441.2627 "Dihydrolipoyllysine-residue acetyltransferase component of pyruvate dehydrogenase complex, mitochondrial OS=Homo sapiens OX=9606 GN=DLAT PE=1 SV=3" 5.84 2544.3 - 1.58E+06 - - - -1.8273 - 1.35 0.068 - 169.8 1 2 0 -0.0016 8 0 0 0 7.58E+07 8.14E+07 - - - 0.4478 0.9998 221125_WJC_METTL3_EV_vs_WT_F03.12859.12859.2 0.00052 20-Sep R.SASFNTDPYVR.E sp|Q9UKV8|AGO2_HUMAN 1 1255.5833 1.48 28979 12859 2 1255.583746 628.7989 Protein argonaute-2 OS=Homo sapiens OX=9606 GN=AGO2 PE=1 SV=3 5.55 2544.4 - 1.54E+06 - - - 0.3425 - 1.783 0.441 - 247.6 1 2 0 0.0004 11 0 0 0 2.91E+07 1.97E+07 - - - 3.8625 0.9999 221125_WJC_METTL3_EV_vs_WT_F03.12864.12864.2 0.000145 20-Oct K.FGDPVVQSDMK[136.11].H "sp|P0DMV8|HS71A_HUMAN,sp|P0DMV9|HS71B_HUMAN,tr|A0A0G2JIW1|A0A0G2JIW1_HUMAN" 3 1229.5842 0.13 28982 12864 2 1229.582497 615.7994 Heat shock 70 kDa protein 1A OS=Homo sapiens OX=9606 GN=HSPA1A PE=1 SV=1 4.21 2545 - 2.57E+07 - - - -1.3639 - 2.312 0.525 - 269.2 1 2 0 -0.0017 11 0 0 0 8.37E+08 6.69E+09 - - - 5.1854 0.9973 221125_WJC_METTL3_EV_vs_WT_F03.12865.12865.2 0.241 14-Jul K.TWTVVDAK.T sp|P13010|XRCC5_HUMAN 1 918.4811 0.9 28983 12865 2 918.481829 460.2478 X-ray repair cross-complementing protein 5 OS=Homo sapiens OX=9606 GN=XRCC5 PE=1 SV=3 5.5 2545.1 - 2.60E+06 - - - 0.8122 - 1.374 0.233 - 256.1 1 2 0 0.0007 8 0 0 0 1.90E+08 2.10E+08 - - - 1.72 0.9997 221125_WJC_METTL3_EV_vs_WT_F03.12866.12866.2 0.00016 16/26 K.GILAADESTGSIAK.R "sp|P04075|ALDOA_HUMAN,tr|H3BQN4|H3BQN4_HUMAN,tr|H3BUH7|H3BUH7_HUMAN,tr|J3KPS3|J3KPS3_HUMAN,tr|H3BPS8|H3BPS8_HUMAN" 5 1331.6933 1.53 28984 12866 2 1331.690247 666.8539 Fructose-bisphosphate aldolase A OS=Homo sapiens OX=9606 GN=ALDOA PE=1 SV=2 4.37 2545.2 - 1.35E+06 - - - -2.2625 - 2.931 0.442 - 1055.2 1 2 0 -0.003 14 0 0 0 2.11E+08 1.38E+08 - - - 5.0032 0.9998 221125_WJC_METTL3_EV_vs_WT_F03.12867.12867.2 1.93E-05 15/26 K.GILAADESTGSIAK[136.11].R "sp|P04075|ALDOA_HUMAN,tr|H3BQN4|H3BQN4_HUMAN,tr|H3BUH7|H3BUH7_HUMAN,tr|J3KPS3|J3KPS3_HUMAN,tr|H3BPS8|H3BPS8_HUMAN" 5 1339.7075 1.52 28985 12867 2 1339.707548 670.861 Fructose-bisphosphate aldolase A OS=Homo sapiens OX=9606 GN=ALDOA PE=1 SV=2 4.37 2545.3 - 1.19E+06 - - - 0.0657 - 2.905 0.355 - 616.6 1 2 0 0.0001 14 0 0 0 2.10E+08 1.38E+08 - - - 4.3392 0.989 221125_WJC_METTL3_EV_vs_WT_F03.12873.12873.2 0.0184 14-Aug K.ELQELYER.L "sp|Q9BYP7|WNK3_HUMAN,tr|A0A087WYK2|A0A087WYK2_HUMAN" 2 1078.5295 4.2 28989 12873 2 1078.52414 540.272 Serine\threonine-protein kinase WNK3 OS=Homo sapiens OX=9606 GN=WNK3 PE=1 SV=3 4.25 2546.1 - 906122 - - - -4.9595 - 1.578 0.33 - 239.9 1 2 0 -0.0053 8 0 0 0 4.87E+07 1.16E+07 - - - 2.8525 0.9969 221125_WJC_METTL3_EV_vs_WT_F03.12876.12876.2 0.0129 20-Sep R.LNAIYQNNLTK.S "sp|P00390|GSHR_HUMAN,tr|A0A2R8YF59|A0A2R8YF59_HUMAN,tr|H0YC68|H0YC68_HUMAN" 3 1290.6932 0.32 28992 12876 2 1290.690038 646.3539 "Glutathione reductase, mitochondrial OS=Homo sapiens OX=9606 GN=GSR PE=1 SV=2" 8.59 2546.5 - 696278 - - - -2.4506 - 1.822 0.228 - 309.3 1 2 0 -0.0032 11 0 0 0 8.79E+06 2.78E+07 - - - 2.347 0.9998 221125_WJC_METTL3_EV_vs_WT_F03.12879.12879.2 1.71E-05 13/22 K.VIEEQLEPAVEK[136.11].L "sp|P42704|LPPRC_HUMAN,tr|A0A804HI14|A0A804HI14_HUMAN,tr|A0A804HL40|A0A804HL40_HUMAN,tr|A0A804HKJ0|A0A804HKJ0_HUMAN,tr|A0A804HKR3|A0A804HKR3_HUMAN,tr|A0A804HIN4|A0A804HIN4_HUMAN,tr|H7C3W8|H7C3W8_HUMAN,tr|A0A804HLG8|A0A804HLG8_HUMAN,tr|A0A804HJA1|A0A804HJA1_HUMAN,tr|A0A804HHY9|A0A804HHY9_HUMAN,tr|A0A804HI40|A0A804HI40_HUMAN,tr|A0A804HJZ1|A0A804HJZ1_HUMAN,tr|A0A804HIQ7|A0A804HIQ7_HUMAN,tr|A0A804HK30|A0A804HK30_HUMAN,tr|A0A804HKI2|A0A804HKI2_HUMAN,tr|A0A804HJI0|A0A804HJI0_HUMAN,tr|A0A804HKK7|A0A804HKK7_HUMAN,tr|A0A804HIG4|A0A804HIG4_HUMAN" 18 1390.7435 1.03 28993 12879 2 1390.742428 696.379 "Leucine-rich PPR motif-containing protein, mitochondrial OS=Homo sapiens OX=9606 GN=LRPPRC PE=1 SV=3" 4.09 2546.9 - 1.74E+06 - - - -0.7787 - 2.38 0.409 - 513 1 2 0 -0.0011 12 0 0 0 6.15E+07 5.96E+07 - - - 4.343 0.9919 221125_WJC_METTL3_EV_vs_WT_F03.12881.12881.2 5.41E-05 20-Oct K.LSAMMGAVAEK.K "sp|Q86U44|MTA70_HUMAN,tr|F5H6D8|F5H6D8_HUMAN,tr|H0YFV6|H0YFV6_HUMAN,tr|B4DTN4|B4DTN4_HUMAN" 4 1106.5464 0.02 28994 12881 2 1107.548418 554.2805 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 6 2547.1 - 1.34E+07 - - - 905.5346 - 2.205 0.491 - 273 1 2 0 1.002 11 0 0 0 7.34E+08 3.19E+10 - - - 4.492 0.9394 221125_WJC_METTL3_EV_vs_WT_F03.12882.12882.2 1.45 16-Jul K.LTMLNTVSK.L "sp|Q99961|SH3G1_HUMAN,tr|M0R0I3|M0R0I3_HUMAN,tr|M0QYE0|M0QYE0_HUMAN" 3 1005.5529 2.24 28995 12882 2 1005.5494 503.7837 Endophilin-A2 OS=Homo sapiens OX=9606 GN=SH3GL1 PE=1 SV=1 8.75 2547.2 - 4.45E+06 - - - -3.4479 - 1.228 0.131 - 102.6 1 2 0 -0.0035 9 0 0 0 6.28E+07 2.81E+07 - - - 0.6017 0.9627 221125_WJC_METTL3_EV_vs_WT_F03.12883.12883.2 0.278 14-Jul K.GIDLTQVK.G "sp|P10515|ODP2_HUMAN,tr|A0A7P0TBE2|A0A7P0TBE2_HUMAN,tr|A0A7P0Z4G4|A0A7P0Z4G4_HUMAN,tr|A0A7P0TAX2|A0A7P0TAX2_HUMAN,tr|A0A7P0TBK2|A0A7P0TBK2_HUMAN,tr|E9PEJ4|E9PEJ4_HUMAN,tr|A0A7P0TAG1|A0A7P0TAG1_HUMAN,tr|A0A7P0TA47|A0A7P0TA47_HUMAN,tr|A0A7P0T997|A0A7P0T997_HUMAN,tr|H0YDD4|H0YDD4_HUMAN" 10 872.4967 0.93 28996 12883 2 872.494481 437.2556 "Dihydrolipoyllysine-residue acetyltransferase component of pyruvate dehydrogenase complex, mitochondrial OS=Homo sapiens OX=9606 GN=DLAT PE=1 SV=3" 5.84 2547.3 - 3.48E+06 - - - -2.5811 - 1.177 0.162 - 128.3 3 2 0 -0.0023 8 0 0 0 7.56E+07 8.14E+07 - - - 0.5152 0.9999 221125_WJC_METTL3_EV_vs_WT_F03.12884.12884.2 0.000297 13/20 K.LENGEIETIAR.F "sp|Q9HDC9|APMAP_HUMAN,tr|H0Y512|H0Y512_HUMAN" 2 1243.6408 1.39 28997 12884 2 1243.64125 622.8277 Adipocyte plasma membrane-associated protein OS=Homo sapiens OX=9606 GN=APMAP PE=1 SV=2 4.25 2547.4 - 3.00E+06 - - - 0.3369 - 2.651 0.428 - 614.7 1 2 0 0.0004 11 0 0 0 1.04E+08 7.49E+07 - - - 4.8395 0.9994 221125_WJC_METTL3_EV_vs_WT_F03.12887.12887.2 0.00335 14-Sep K.TWTVVDAK[136.11].T sp|P13010|XRCC5_HUMAN 1 926.4953 0.91 28998 12887 2 926.493459 464.2549 X-ray repair cross-complementing protein 5 OS=Homo sapiens OX=9606 GN=XRCC5 PE=1 SV=3 5.5 2547.8 - 8.41E+06 - - - -1.9676 - 1.727 0.397 - 431 1 2 0 -0.0018 8 0 0 0 1.90E+08 2.10E+08 - - - 3.6205 0.9998 221125_WJC_METTL3_EV_vs_WT_F03.12888.12888.3 0.000384 14/36 K.IAGYVTHLMK[136.11].R "sp|P08708|RS17_HUMAN,tr|H3BNC9|H3BNC9_HUMAN,tr|H0YN88|H0YN88_HUMAN,tr|A0A075B716|A0A075B716_HUMAN" 4 1139.6253 0.001 28999 12888 3 1139.622168 380.8824 40S ribosomal protein S17 OS=Homo sapiens OX=9606 GN=RPS17 PE=1 SV=2 8.6 2547.8 - 3.42E+06 - - - -2.7053 - 2.126 0.422 - 173.2 1 2 0 -0.0031 10 0 0 0 0.00E+00 1.47E+08 - - - 5.4467 0.9359 221125_WJC_METTL3_EV_vs_WT_F03.12889.12889.2 0.000118 16-Jul K.YVHYEIDAC[160.03].M "sp|Q86U44|MTA70_HUMAN,tr|H0YFV6|H0YFV6_HUMAN" 2 1168.4859 - 29000 12889 2 1168.481868 585.2502 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 4.35 2547.9 - 3.95E+06 - - - -3.4592 - 1.643 0.506 - 157.1 1 1 0 -0.004 9 0 0 0 - - - - - 4.2135 0.9997 221125_WJC_METTL3_EV_vs_WT_F03.12890.12890.2 0.00965 16-Oct R.FGISSVPTK.G "sp|P82979|SARNP_HUMAN,tr|F8VZQ9|F8VZQ9_HUMAN,tr|H0YHG0|H0YHG0_HUMAN" 3 934.5124 0.6 29001 12890 2 934.511425 468.2635 SAP domain-containing ribonucleoprotein OS=Homo sapiens OX=9606 GN=SARNP PE=1 SV=3 8.75 2548.1 - 3.44E+06 - - - -1.0251 - 1.953 0.402 - 302.3 1 2 0 -0.001 9 0 0 0 1.10E+08 1.83E+08 - - - 3.9464 0.9998 221125_WJC_METTL3_EV_vs_WT_F03.12891.12891.2 0.000647 22-Dec K.VIEEQLEPAVEK.L "sp|P42704|LPPRC_HUMAN,tr|A0A804HI14|A0A804HI14_HUMAN,tr|A0A804HL40|A0A804HL40_HUMAN,tr|A0A804HKJ0|A0A804HKJ0_HUMAN,tr|A0A804HKR3|A0A804HKR3_HUMAN,tr|A0A804HIN4|A0A804HIN4_HUMAN,tr|H7C3W8|H7C3W8_HUMAN,tr|A0A804HLG8|A0A804HLG8_HUMAN,tr|A0A804HJA1|A0A804HJA1_HUMAN,tr|A0A804HHY9|A0A804HHY9_HUMAN,tr|A0A804HI40|A0A804HI40_HUMAN,tr|A0A804HJZ1|A0A804HJZ1_HUMAN,tr|A0A804HIQ7|A0A804HIQ7_HUMAN,tr|A0A804HK30|A0A804HK30_HUMAN,tr|A0A804HKI2|A0A804HKI2_HUMAN,tr|A0A804HJI0|A0A804HJI0_HUMAN,tr|A0A804HKK7|A0A804HKK7_HUMAN,tr|A0A804HIG4|A0A804HIG4_HUMAN" 18 1382.7293 1.03 29002 12891 2 1382.730167 692.3719 "Leucine-rich PPR motif-containing protein, mitochondrial OS=Homo sapiens OX=9606 GN=LRPPRC PE=1 SV=3" 4.09 2548.2 - 1.63E+06 - - - 0.6191 - 2.284 0.43 - 357.4 1 2 0 0.0009 12 0 0 0 6.16E+07 5.96E+07 - - - 4.3899 0.9997 221125_WJC_METTL3_EV_vs_WT_F03.12892.12892.2 0.0131 18-Oct R.DLTLEENQVK[136.11].K "sp|Q14683|SMC1A_HUMAN,tr|G8JLG1|G8JLG1_HUMAN" 2 1195.6176 2.45 29003 12892 2 1195.617814 598.8161 Structural maintenance of chromosomes protein 1A OS=Homo sapiens OX=9606 GN=SMC1A PE=1 SV=2 4.14 2548.3 - 1.15E+06 - - - 0.1932 - 2.039 0.326 - 351 1 2 0 0.0002 10 0 0 0 6.03E+07 2.46E+07 - - - 3.4375 1 221125_WJC_METTL3_EV_vs_WT_F03.12895.12895.2 1.13E-09 20-Dec K.FGDPVVQSDMK.H "sp|P0DMV8|HS71A_HUMAN,sp|P0DMV9|HS71B_HUMAN,tr|A0A0G2JIW1|A0A0G2JIW1_HUMAN" 3 1221.57 0.13 29004 12895 2 1221.5659 611.7923 Heat shock 70 kDa protein 1A OS=Homo sapiens OX=9606 GN=HSPA1A PE=1 SV=1 4.21 2548.7 - 1.94E+07 - - - -3.3351 - 2.484 0.649 - 390.7 1 2 0 -0.0041 11 0 0 0 8.38E+08 6.69E+09 - - - 6.2946 0.9998 221125_WJC_METTL3_EV_vs_WT_F03.12897.12897.2 0.000182 16-Oct K.QGTYGGYFR.D "sp|Q99613|EIF3C_HUMAN,sp|B5ME19|EIFCL_HUMAN" 2 1047.4774 1.07 29005 12897 2 1047.476826 524.746 Eukaryotic translation initiation factor 3 subunit C OS=Homo sapiens OX=9606 GN=EIF3C PE=1 SV=1 8.59 2548.9 - 3.44E+06 - - - -0.5423 - 1.681 0.507 - 362.7 1 2 0 -0.0006 9 0 0 0 1.17E+08 1.10E+08 - - - 4.2881 0.9887 221125_WJC_METTL3_EV_vs_WT_F03.12898.12898.2 0.00891 16-Nov R.EQIMVLNNK.F "sp|Q7Z794|K2C1B_HUMAN,tr|F8VS61|F8VS61_HUMAN" 2 1087.5696 235.34 29006 12898 2 1087.566141 544.7921 "Keratin, type II cytoskeletal 1b OS=Homo sapiens OX=9606 GN=KRT77 PE=1 SV=3" 6.1 2549 - 1.43E+06 - - - -3.1621 - 1.964 0.095 - 453.3 1 2 0 -0.0034 9 0 0 0 4.23E+07 1.80E+05 - - - 1.6944 0.9942 221125_WJC_METTL3_EV_vs_WT_F03.12900.12900.2 0.0383 18-Sep R.DLTLEENQVK.K "sp|Q14683|SMC1A_HUMAN,tr|G8JLG1|G8JLG1_HUMAN" 2 1187.6034 2.53 29008 12900 2 1187.598239 594.809 Structural maintenance of chromosomes protein 1A OS=Homo sapiens OX=9606 GN=SMC1A PE=1 SV=2 4.14 2549.2 - 1.50E+06 - - - -4.3314 - 1.885 0.302 - 250.1 1 2 0 -0.0051 10 0 0 0 6.25E+07 2.47E+07 - - - 3.0394 0.997 221125_WJC_METTL3_EV_vs_WT_F03.12915.12915.2 0.00615 16-Aug R.VITIMQNPR[166.11].Q sp|P62269|RS18_HUMAN 1 1080.5989 0.87 29017 12915 2 1080.595648 541.3067 40S ribosomal protein S18 OS=Homo sapiens OX=9606 GN=RPS18 PE=1 SV=3 9.72 2550.9 - 500016 - - - -3.028 - 1.549 0.333 - 195.8 1 2 0 -0.0033 9 0 0 0 6.02E+08 6.94E+08 - - - 2.7655 1 221125_WJC_METTL3_EV_vs_WT_F03.12916.12916.2 3.57E-07 13/22 R.FLEQQNQVLQTK.W "sp|Q7Z794|K2C1B_HUMAN,sp|P04264|K2C1_HUMAN,sp|P35908|K22E_HUMAN" 3 1474.778 999 29018 12916 2 1474.774802 738.3963 "Keratin, type II cytoskeletal 1b OS=Homo sapiens OX=9606 GN=KRT77 PE=1 SV=3" 6 2551.1 - 1.81E+06 - - - -2.1637 - 2.688 0.568 - 462.4 1 2 0 -0.0032 12 0 0 0 3.99E+09 0.00E+00 - - - 5.8369 0.9999 221125_WJC_METTL3_EV_vs_WT_F03.12918.12918.2 0.000318 14/20 K.LENGEIETIAR[166.11].F "sp|Q9HDC9|APMAP_HUMAN,tr|H0Y512|H0Y512_HUMAN" 2 1253.6491 1.41 29019 12918 2 1253.647308 627.8318 Adipocyte plasma membrane-associated protein OS=Homo sapiens OX=9606 GN=APMAP PE=1 SV=2 4.25 2551.3 - 2.47E+06 - - - -1.4302 - 2.782 0.48 - 812 1 2 0 -0.0018 11 0 0 0 1.04E+08 7.38E+07 - - - 5.3536 0.9995 221125_WJC_METTL3_EV_vs_WT_F03.12920.12920.2 0.0196 14-Aug R.NGYGFINR.N "sp|Q9Y2T7|YBOX2_HUMAN,sp|P67809|YBOX1_HUMAN,sp|P16989|YBOX3_HUMAN,tr|C9J5V9|C9J5V9_HUMAN" 4 939.4563 1.03 29020 12920 2 939.454744 470.7354 Y-box-binding protein 2 OS=Homo sapiens OX=9606 GN=YBX2 PE=1 SV=2 8.75 2551.5 - 3.15E+07 - - - -1.619 - 1.824 0.384 - 311.5 1 2 0 -0.0015 8 0 0 0 9.81E+08 9.49E+08 - - - 3.6894 0.8873 221125_WJC_METTL3_EV_vs_WT_F03.12921.12921.2 2.72E-05 16-Aug F.AFVQYVNER.N "sp|P07910|HNRPC_HUMAN,tr|G3V251|G3V251_HUMAN,tr|B4DY08|B4DY08_HUMAN,tr|G3V575|G3V575_HUMAN,tr|B4DSU6|B4DSU6_HUMAN,tr|G3V3K6|G3V3K6_HUMAN,tr|B2R5W2|B2R5W2_HUMAN,tr|G3V4C1|G3V4C1_HUMAN,tr|G3V576|G3V576_HUMAN,tr|G3V5X6|G3V5X6_HUMAN,tr|G3V4W0|G3V4W0_HUMAN,tr|G3V555|G3V555_HUMAN,tr|G3V4M8|G3V4M8_HUMAN,tr|G3V2Q1|G3V2Q1_HUMAN" 14 1124.5615 1.4 29021 12921 2 1124.556228 563.288 Heterogeneous nuclear ribonucleoproteins C1\C2 OS=Homo sapiens OX=9606 GN=HNRNPC PE=1 SV=4 6.05 2551.5 - 2.68E+06 - - - -4.6507 - 1.951 0.49 - 340.1 1 1 0 -0.0052 9 0 0 0 1.88E+08 1.34E+08 - - - 4.592 0.9999 221125_WJC_METTL3_EV_vs_WT_F03.12922.12922.2 3.06E-05 13/22 K.AVANQTSATFLR[166.11].V sp|P62191|PRS4_HUMAN 1 1287.6811 0.59 29022 12922 2 1287.681879 644.8478 26S proteasome regulatory subunit 4 OS=Homo sapiens OX=9606 GN=PSMC1 PE=1 SV=1 9.79 2551.7 - 1.16E+06 - - - 0.6283 - 3.013 0.511 - 719.2 1 2 0 0.0008 12 0 0 0 4.51E+07 7.68E+07 - - - 5.717 0.9996 221125_WJC_METTL3_EV_vs_WT_F03.12928.12928.2 0.00114 18-Nov R.RGSPLLIGVR.S "sp|Q06210|GFPT1_HUMAN,sp|O94808|GFPT2_HUMAN,tr|A0A6I8PRN4|A0A6I8PRN4_HUMAN,tr|E5RJP4|E5RJP4_HUMAN,tr|A0A6I8PTT9|A0A6I8PTT9_HUMAN" 5 1066.6611 1.16 29026 12928 2 1066.660871 534.3378 Glutamine--fructose-6-phosphate aminotransferase [isomerizing] 1 OS=Homo sapiens OX=9606 GN=GFPT1 PE=1 SV=3 12 2552.4 - 1.33E+06 - - - -0.2269 - 1.739 0.37 - 166 1 2 0 -0.0002 10 0 0 0 4.10E+07 3.53E+07 - - - 3.3182 0.9998 221125_WJC_METTL3_EV_vs_WT_F03.12929.12929.2 2.86E-05 24-Dec K.LIAINANDPEASK[136.11].F "sp|Q9H2U2|IPYR2_HUMAN,tr|D6R967|D6R967_HUMAN,tr|H0Y9D8|H0Y9D8_HUMAN" 3 1362.7234 0.81 29027 12929 2 1362.721746 682.369 "Inorganic pyrophosphatase 2, mitochondrial OS=Homo sapiens OX=9606 GN=PPA2 PE=1 SV=2" 4.37 2552.6 - 969731 - - - -1.2468 - 2.095 0.492 - 304.6 1 2 0 -0.0017 13 0 0 0 1.13E+07 1.40E+07 - - - 4.5725 0.9994 221125_WJC_METTL3_EV_vs_WT_F03.12932.12932.2 0.00767 18-Dec R.LQSLTENLTK.E sp|P15924|DESP_HUMAN 1 1145.6292 13.69 29028 12932 2 1145.626559 573.8219 Desmoplakin OS=Homo sapiens OX=9606 GN=DSP PE=1 SV=3 6 2553 - 3.27E+06 - - - -2.3079 - 2.311 0.344 - 367.8 1 2 0 -0.0026 10 0 0 0 2.44E+08 1.78E+07 - - - 3.9192 0.98 221125_WJC_METTL3_EV_vs_WT_F03.12933.12933.2 0.000112 14-Aug R.SHSVFSVT.L "sp|P52732|KIF11_HUMAN,tr|A0A7I2YQY4|A0A7I2YQY4_HUMAN,tr|A0A7I2V3A9|A0A7I2V3A9_HUMAN,tr|A0A7I2V3V3|A0A7I2V3V3_HUMAN" 4 862.4185 - 29029 12933 2 862.417209 432.2165 Kinesin-like protein KIF11 OS=Homo sapiens OX=9606 GN=KIF11 PE=1 SV=2 6.46 2553.1 - 2.86E+06 - - - -1.4761 - 1.829 0.417 - 238.6 1 1 0 -0.0013 8 0 0 0 - - - - - 3.9415 0.9983 221125_WJC_METTL3_EV_vs_WT_F03.12935.12935.2 0.365 14-Aug K.VSGDIFSR.L "sp|A8K0Z3|WASH1_HUMAN,sp|C4AMC7|WASH3_HUMAN,sp|Q6VEQ5|WASH2_HUMAN" 3 879.445 1.45 29031 12935 2 879.443565 440.7298 WASH complex subunit 1 OS=Homo sapiens OX=9606 GN=WASHC1 PE=1 SV=2 5.81 2553.3 - 2.32E+06 - - - -1.667 - 1.584 0.267 - 162.1 1 2 0 -0.0015 8 0 0 0 6.87E+07 4.72E+07 - - - 2.3998 0.9998 221125_WJC_METTL3_EV_vs_WT_F03.12936.12936.2 0.000126 16-Oct R.VITIMQNPR.Q sp|P62269|RS18_HUMAN 1 1070.5907 0.87 29032 12936 2 1070.59085 536.3026 40S ribosomal protein S18 OS=Homo sapiens OX=9606 GN=RPS18 PE=1 SV=3 9.72 2553.4 - 2.12E+06 - - - 0.1868 - 2.045 0.444 - 428.5 1 2 0 0.0002 9 0 0 0 6.02E+08 6.94E+08 - - - 4.39 0.9997 221125_WJC_METTL3_EV_vs_WT_F03.12937.12937.2 0.000186 20-Dec K.YLDNPNALTER.E "sp|Q63ZY3|KANK2_HUMAN,tr|K7EIU4|K7EIU4_HUMAN" 2 1304.6361 2.47 29033 12937 2 1304.633827 653.3253 KN motif and ankyrin repeat domain-containing protein 2 OS=Homo sapiens OX=9606 GN=KANK2 PE=1 SV=1 4.37 2553.5 - 671158 - - - -1.7269 - 1.7 0.509 - 400.4 1 2 0 -0.0023 11 0 0 0 2.17E+07 8.79E+06 - - - 4.2352 0.9998 221125_WJC_METTL3_EV_vs_WT_F03.12940.12940.2 0.000192 14/24 K.AINQGGLTSVAVR[166.11].G "sp|P60900|PSA6_HUMAN,tr|G3V5Z7|G3V5Z7_HUMAN,tr|G3V295|G3V295_HUMAN,tr|G3V3I1|G3V3I1_HUMAN,tr|G3V3U4|G3V3U4_HUMAN" 5 1294.7233 0.78 29034 12940 2 1294.720967 648.3689 Proteasome subunit alpha type-6 OS=Homo sapiens OX=9606 GN=PSMA6 PE=1 SV=1 9.79 2553.9 - 2.48E+06 - - - -1.778 - 2.765 0.477 - 791.1 1 2 0 -0.0023 13 0 0 0 7.01E+07 8.94E+07 - - - 5.1737 0.9299 221125_WJC_METTL3_EV_vs_WT_F03.12941.12941.2 0.348 14-Aug K.SVNELIYK.R "sp|P18124|RL7_HUMAN,tr|A8MUD9|A8MUD9_HUMAN" 2 964.5229 0.49 29035 12941 2 964.527889 483.2687 60S ribosomal protein L7 OS=Homo sapiens OX=9606 GN=RPL7 PE=1 SV=1 5.72 2554 - 2.35E+06 - - - 5.1238 - 1.346 0.194 - 167.8 1 2 0 0.0049 8 0 0 0 4.09E+07 8.28E+07 - - - 1.3685 0.9962 221125_WJC_METTL3_EV_vs_WT_F03.12942.12942.3 0.0483 Aug-44 R.FLEQQNQVLQTK.W "sp|Q7Z794|K2C1B_HUMAN,sp|P04264|K2C1_HUMAN,sp|P35908|K22E_HUMAN" 3 1474.778 98.03 29036 12942 3 1474.775641 492.5999 "Keratin, type II cytoskeletal 1b OS=Homo sapiens OX=9606 GN=KRT77 PE=1 SV=3" 6 2554 - 3.39E+06 - - - -1.5948 - 1.516 0.262 - 77.2 1 2 0 -0.0024 12 0 0 0 3.71E+08 3.78E+06 - - - 2.6137 0.9999 221125_WJC_METTL3_EV_vs_WT_F03.12943.12943.2 3.90E-06 13/24 K.LIAINANDPEASK.F "sp|Q9H2U2|IPYR2_HUMAN,tr|D6R967|D6R967_HUMAN,tr|H0Y9D8|H0Y9D8_HUMAN" 3 1354.7092 0.81 29037 12943 2 1354.709872 678.3619 "Inorganic pyrophosphatase 2, mitochondrial OS=Homo sapiens OX=9606 GN=PPA2 PE=1 SV=2" 4.37 2554.2 - 885909 - - - 0.4628 - 2.325 0.569 - 583.3 1 2 0 0.0006 13 0 0 0 1.13E+07 1.40E+07 - - - 5.4089 0.9991 221125_WJC_METTL3_EV_vs_WT_F03.12944.12944.2 0.0412 20-Aug K.VVQETVLVEER[166.11].R "sp|Q9Y2J2|E41L3_HUMAN,tr|A0A0A0MRA8|A0A0A0MRA8_HUMAN,tr|A8K968|A8K968_HUMAN,tr|A0A0J9YY18|A0A0J9YY18_HUMAN,tr|A0A0A0MSA4|A0A0A0MSA4_HUMAN,tr|A0A0J9YW31|A0A0J9YW31_HUMAN" 6 1309.7117 2.78 29038 12944 2 1309.709736 655.8631 Band 4.1-like protein 3 OS=Homo sapiens OX=9606 GN=EPB41L3 PE=1 SV=2 4.25 2554.3 - 644587 - - - -1.5003 - 2.039 0.257 - 213.4 1 2 0 -0.002 11 0 0 0 3.19E+07 1.15E+07 - - - 2.866 0.9997 221125_WJC_METTL3_EV_vs_WT_F03.12947.12947.2 0.00148 16-Aug K.ESTATTFLR.Q "sp|Q9BSR8|YIPF4_HUMAN,tr|H7C0D5|H7C0D5_HUMAN" 2 1024.5189 0.97 29039 12947 2 1024.518556 513.2667 Protein YIPF4 OS=Homo sapiens OX=9606 GN=YIPF4 PE=1 SV=1 6.1 2554.7 - 4.22E+06 - - - -0.3602 - 1.766 0.385 - 384.3 1 2 0 -0.0004 9 0 0 0 8.49E+07 8.75E+07 - - - 3.5298 0.9289 221125_WJC_METTL3_EV_vs_WT_F03.12948.12948.2 0.0436 14-Aug K.GIVEFASK[136.11].P sp|P23246|SFPQ_HUMAN 1 857.4738 0.84 29040 12948 2 857.472343 429.7442 "Splicing factor, proline- and glutamine-rich OS=Homo sapiens OX=9606 GN=SFPQ PE=1 SV=2" 6 2554.8 - 1.86E+06 - - - -1.7213 - 1.537 0.317 - 221.8 1 1 0 -0.0015 8 0 0 0 3.44E+07 4.11E+07 - - - 2.6783 0.9989 221125_WJC_METTL3_EV_vs_WT_F03.12949.12949.2 0.00207 14-Aug R.SFEEAFQK[136.11].A "sp|P27708|PYR1_HUMAN,tr|F8VPD4|F8VPD4_HUMAN" 2 992.4695 0.56 29041 12949 2 992.46747 497.242 CAD protein OS=Homo sapiens OX=9606 GN=CAD PE=1 SV=3 4.53 2554.9 - 1.31E+06 - - - -2.0071 - 1.406 0.4 - 172.1 1 2 0 -0.002 8 0 0 0 2.11E+07 3.76E+07 - - - 3.0225 0.9999 221125_WJC_METTL3_EV_vs_WT_F03.12951.12951.2 9.73E-05 13/22 R.ALEEANADLEVK.L "sp|P02533|K1C14_HUMAN,sp|P08779|K1C16_HUMAN,sp|P19012|K1C15_HUMAN,sp|P13646|K1C13_HUMAN,tr|K7EMD9|K7EMD9_HUMAN,tr|K7ERE3|K7ERE3_HUMAN" 6 1300.6511 999 29042 12951 2 1300.650522 651.3328 "Keratin, type I cytoskeletal 14 OS=Homo sapiens OX=9606 GN=KRT14 PE=1 SV=4" 4 2555.1 - 2.23E+06 - - - -0.4144 - 2.609 0.428 - 531.2 1 2 0 -0.0005 12 0 0 0 1.49E+08 0.00E+00 - - - 4.7252 0.8402 221125_WJC_METTL3_EV_vs_WT_F03.12953.12953.2 0.832 14-Jun K.SVNELIYK[136.11].R "sp|P18124|RL7_HUMAN,tr|A8MUD9|A8MUD9_HUMAN" 2 972.5371 0.46 29043 12953 2 972.541888 487.2758 60S ribosomal protein L7 OS=Homo sapiens OX=9606 GN=RPL7 PE=1 SV=1 5.72 2555.3 - 2.46E+06 - - - 4.8749 - 1.248 0.12 - 88.9 1 2 0 0.0047 8 0 0 0 4.13E+07 9.05E+07 - - - 0.594 0.7656 221125_WJC_METTL3_EV_vs_WT_F03.12954.12954.2 0.0231 14-Aug K.GIVEFASK.P sp|P23246|SFPQ_HUMAN 1 849.4596 0.84 29044 12954 2 849.456067 425.7371 "Splicing factor, proline- and glutamine-rich OS=Homo sapiens OX=9606 GN=SFPQ PE=1 SV=2" 6 2555.4 - 1.89E+06 - - - -4.1815 - 1.496 0.381 - 215.5 1 1 0 -0.0036 8 0 0 0 3.44E+07 4.11E+07 - - - 3.0688 0.9998 221125_WJC_METTL3_EV_vs_WT_F03.12955.12955.2 1.58E-07 15/24 K.AINQGGLTSVAVR.G "sp|P60900|PSA6_HUMAN,tr|G3V5Z7|G3V5Z7_HUMAN,tr|G3V295|G3V295_HUMAN,tr|G3V3I1|G3V3I1_HUMAN,tr|G3V3U4|G3V3U4_HUMAN" 5 1284.715 0.78 29045 12955 2 1284.712754 643.3648 Proteasome subunit alpha type-6 OS=Homo sapiens OX=9606 GN=PSMA6 PE=1 SV=1 9.79 2555.6 - 3.38E+06 - - - -1.7475 - 3.017 0.464 - 775.4 1 2 0 -0.0022 13 0 0 0 7.01E+07 8.94E+07 - - - 5.3015 0.8425 221125_WJC_METTL3_EV_vs_WT_F03.12956.12956.2 0.0772 14-Sep K.SSLINSLK[136.11].R "sp|Q9NVN8|GNL3L_HUMAN,sp|Q9BVP2|GNL3_HUMAN,tr|A0A6I8PL80|A0A6I8PL80_HUMAN,tr|A0A6I8PS19|A0A6I8PS19_HUMAN" 4 868.5109 1.7 29046 12956 2 868.505957 435.2627 Guanine nucleotide-binding protein-like 3-like protein OS=Homo sapiens OX=9606 GN=GNL3L PE=1 SV=1 8.47 2555.7 - 845290 - - - -5.7293 - 1.387 0.132 - 227.6 1 2 0 -0.005 8 0 0 0 1.29E+08 7.59E+07 - - - 1.001 0.9998 221125_WJC_METTL3_EV_vs_WT_F03.12960.12960.2 0.00718 22-Nov R.ALEEANTELEVK.L "sp|Q04695|K1C17_HUMAN,tr|K7EPJ9|K7EPJ9_HUMAN" 2 1344.6773 11.55 29049 12960 2 1344.677365 673.3459 "Keratin, type I cytoskeletal 17 OS=Homo sapiens OX=9606 GN=KRT17 PE=1 SV=2" 4.09 2556.1 - 553055 - - - 0.0662 - 2.379 0.418 - 333.6 1 2 0 0.0001 12 0 0 0 6.18E+07 5.35E+06 - - - 4.4087 1 221125_WJC_METTL3_EV_vs_WT_F03.12962.12962.2 2.99E-06 14/22 K.AVANQTSATFLR.V sp|P62191|PRS4_HUMAN 1 1277.6728 0.59 29050 12962 2 1277.670671 639.8437 26S proteasome regulatory subunit 4 OS=Homo sapiens OX=9606 GN=PSMC1 PE=1 SV=1 9.79 2556.4 - 2.38E+06 - - - -1.6663 - 3.034 0.553 - 859.8 1 2 0 -0.0021 12 0 0 0 4.51E+07 7.68E+07 - - - 6.0451 0.9994 221125_WJC_METTL3_EV_vs_WT_F03.12963.12963.2 0.00018 16-Aug R.EVLDQVC[160.03]YR[166.11].V sp|Q15459|SF3A1_HUMAN 1 1190.5629 0.74 29051 12963 2 1190.560217 596.2887 Splicing factor 3A subunit 1 OS=Homo sapiens OX=9606 GN=SF3A1 PE=1 SV=1 4.37 2556.4 - 1.83E+06 - - - -2.2771 - 1.759 0.451 - 283.2 1 2 0 -0.0027 9 0 0 0 3.13E+07 4.25E+07 - - - 4.0051 0.9331 221125_WJC_METTL3_EV_vs_WT_F03.12967.12967.2 0.763 22-Aug K.IMQQETSVPTLK[136.11].Q sp|Q7Z417|NUFP2_HUMAN 1 1381.7367 2.17 29055 12967 2 1381.731533 691.8756 Nuclear fragile X mental retardation-interacting protein 2 OS=Homo sapiens OX=9606 GN=NUFIP2 PE=1 SV=1 6 2556.9 - 537294 - - - -3.7048 - 1.239 0.161 - 63.2 2 2 0 -0.0051 12 0 0 0 1.16E+07 5.34E+06 - - - 0.6579 0.9998 221125_WJC_METTL3_EV_vs_WT_F03.12970.12970.2 0.014 22-Nov R.AQPSVSLGAAYR.A sp|Q96PK6|RBM14_HUMAN 1 1218.6357 2.23 29057 12970 2 1218.634585 610.3251 RNA-binding protein 14 OS=Homo sapiens OX=9606 GN=RBM14 PE=1 SV=2 8.79 2557.3 - 8.14E+06 - - - -0.9035 - 2.148 0.436 - 452.3 1 2 0 -0.0011 12 0 0 0 1.14E+09 5.10E+08 - - - 4.2726 0.9988 221125_WJC_METTL3_EV_vs_WT_F03.12972.12972.3 0.906 14/32 K.LLPLEEHYR.F "sp|Q9NZN3|EHD3_HUMAN,sp|Q9NZN4|EHD2_HUMAN,sp|Q9H4M9|EHD1_HUMAN,tr|C9JC03|C9JC03_HUMAN,tr|C9JIJ3|C9JIJ3_HUMAN,tr|C9IZH1|C9IZH1_HUMAN,tr|A0A024R571|A0A024R571_HUMAN" 7 1168.6241 1.23 29058 12972 3 1168.622465 390.5486 EH domain-containing protein 3 OS=Homo sapiens OX=9606 GN=EHD3 PE=1 SV=2 5.4 2557.5 - 1.08E+06 - - - -1.3631 - 2.088 0.23 - 234.9 1 2 0 -0.0016 9 0 0 0 2.01E+07 1.64E+07 - - - 3.3226 0.9988 221125_WJC_METTL3_EV_vs_WT_F03.12976.12976.2 0.0335 16-Oct K.NVIAALNSR.T "sp|Q8N766|EMC1_HUMAN,tr|Q5TG59|Q5TG59_HUMAN" 2 956.5403 1.03 29062 12976 2 956.538969 479.2774 ER membrane protein complex subunit 1 OS=Homo sapiens OX=9606 GN=EMC1 PE=1 SV=1 9.75 2557.8 - 1.40E+06 - - - -1.4218 - 1.917 0.222 - 335.3 1 2 0 -0.0014 9 0 0 0 3.16E+07 3.07E+07 - - - 2.563 0.9999 221125_WJC_METTL3_EV_vs_WT_F03.12978.12978.3 0.0138 Dec-32 K.LLPLEEHYR[166.11].F "sp|Q9NZN3|EHD3_HUMAN,sp|Q9NZN4|EHD2_HUMAN,sp|Q9H4M9|EHD1_HUMAN,tr|C9JC03|C9JC03_HUMAN,tr|C9JIJ3|C9JIJ3_HUMAN,tr|C9IZH1|C9IZH1_HUMAN,tr|A0A024R571|A0A024R571_HUMAN" 7 1178.6323 1.26 29064 12978 3 1178.63167 393.8847 EH domain-containing protein 3 OS=Homo sapiens OX=9606 GN=EHD3 PE=1 SV=2 5.4 2558.1 - 1.11E+06 - - - -0.5583 - 2.139 0.372 - 190.9 1 2 0 -0.0007 9 0 0 0 2.17E+07 1.73E+07 - - - 4.9788 0.9759 221125_WJC_METTL3_EV_vs_WT_F03.12982.12982.2 0.285 16-Jun K.NVIHPFLSR[166.11].S "sp|P26640|SYVC_HUMAN,tr|A0A140T936|A0A140T936_HUMAN" 2 1091.6115 42.76 29068 12982 2 1091.60817 546.813 Valine--tRNA ligase OS=Homo sapiens OX=9606 GN=VARS1 PE=1 SV=4 9.76 2558.6 - 286154 - - - -3.0808 - 1.376 0.151 - 107.8 1 2 0 -0.0034 9 0 0 0 2.85E+08 6.67E+06 - - - 1.0786 0.7821 221125_WJC_METTL3_EV_vs_WT_F03.12985.12985.3 0.282 Oct-40 F.GVISNHLILNK[136.11].L "sp|P43243|MATR3_HUMAN,tr|D6RE02|D6RE02_HUMAN,tr|B3KM87|B3KM87_HUMAN,tr|A8MXP9|A8MXP9_HUMAN,tr|D6R991|D6R991_HUMAN,tr|D6RBK5|D6RBK5_HUMAN,tr|A0A0R4J2E8|A0A0R4J2E8_HUMAN,tr|D6RIA2|D6RIA2_HUMAN,tr|H0Y8T4|H0Y8T4_HUMAN,tr|D6REM6|D6REM6_HUMAN,tr|D6RBI2|D6RBI2_HUMAN" 11 1214.7227 1.26 29069 12985 3 1214.721047 405.9148 Matrin-3 OS=Homo sapiens OX=9606 GN=MATR3 PE=1 SV=2 8.76 2559 - 3.08E+06 - - - -1.3254 - 1.865 0.219 - 86.1 1 1 0 -0.0016 11 0 0 0 9.74E+07 7.72E+07 - - - 2.7518 0.9998 221125_WJC_METTL3_EV_vs_WT_F03.12986.12986.2 0.000723 16-Sep R.DLPNALDEK.Q sp|Q9NVJ2|ARL8B_HUMAN 1 1013.5029 1.42 29070 12986 2 1013.502053 507.7587 ADP-ribosylation factor-like protein 8B OS=Homo sapiens OX=9606 GN=ARL8B PE=1 SV=1 4.03 2559 - 3.91E+06 - - - -0.8752 - 1.749 0.459 - 254.6 1 2 0 -0.0009 9 0 0 0 1.09E+08 7.71E+07 - - - 4.0482 0.9908 221125_WJC_METTL3_EV_vs_WT_F03.12988.12988.2 0.37 22-Aug M.VYISNGQVLDSR[166.11].S "sp|Q9Y6D0|SELK_HUMAN,tr|F8WAX7|F8WAX7_HUMAN,tr|F6XHT0|F6XHT0_HUMAN" 3 1359.7022 0.89 29072 12988 2 1359.703227 680.8584 Selenoprotein K OS=Homo sapiens OX=9606 GN=SELENOK PE=1 SV=3 5.81 2559.2 - 952436 - - - 0.756 - 1.51 0.109 - 128.4 2 2 0 0.001 12 0 0 0 1.23E+07 1.38E+07 - - - 0.7956 0.9872 221125_WJC_METTL3_EV_vs_WT_F03.12992.12992.2 0.274 14-Jun R.EWTC[160.03]PNLK[136.11].K "sp|Q9NX05|F120C_HUMAN,sp|Q9NZB2|F120A_HUMAN,tr|A0A0C4DG79|A0A0C4DG79_HUMAN,tr|F8W881|F8W881_HUMAN" 4 1054.4997 2.15 29076 12992 2 1054.496429 528.2571 Constitutive coactivator of PPAR-gamma-like protein 2 OS=Homo sapiens OX=9606 GN=FAM120C PE=1 SV=3 6.09 2559.7 - 448465 - - - -3.1171 - 1.308 0.233 - 119.7 1 2 0 -0.0033 8 0 0 0 1.25E+07 5.82E+06 - - - 1.5707 0.9991 221125_WJC_METTL3_EV_vs_WT_F03.12995.12995.2 0.00406 16-Aug K.EIAEAYLGK[136.11].T "sp|P11142|HSP7C_HUMAN,tr|E9PQQ4|E9PQQ4_HUMAN,tr|E9PKE3|E9PKE3_HUMAN,tr|E9PN89|E9PN89_HUMAN,tr|E9PLF4|E9PLF4_HUMAN,tr|E9PI65|E9PI65_HUMAN,tr|E9PK54|E9PK54_HUMAN,tr|E9PPY6|E9PPY6_HUMAN,tr|E9PQK7|E9PQK7_HUMAN" 9 1000.5321 0.16 29078 12995 2 1000.531104 501.2733 Heat shock cognate 71 kDa protein OS=Homo sapiens OX=9606 GN=HSPA8 PE=1 SV=1 4.53 2560.1 - 1.30E+07 - - - -0.9575 - 1.675 0.281 - 286.9 1 2 0 -0.001 9 0 0 0 9.78E+07 5.97E+08 - - - 2.6084 0.7966 221125_WJC_METTL3_EV_vs_WT_F03.12997.12997.2 0.416 12-May R.HFGMLSR[166.11].W "sp|Q7L3B6|CD37L_HUMAN,tr|B1AL69|B1AL69_HUMAN" 2 856.4253 0.85 29079 12997 2 856.421147 429.2199 Hsp90 co-chaperone Cdc37-like 1 OS=Homo sapiens OX=9606 GN=CDC37L1 PE=1 SV=1 9.76 2560.3 - 3.42E+06 - - - -4.8632 - 0.967 0.195 - 66.6 1 2 0 -0.0042 7 0 0 0 6.91E+07 8.13E+07 - - - 0.3736 0.9999 221125_WJC_METTL3_EV_vs_WT_F03.12998.12998.2 0.000132 20-Nov R.SPGAPGPLTLK.E "sp|Q15942|ZYX_HUMAN,tr|H0Y2Y8|H0Y2Y8_HUMAN,tr|C9JJK5|C9JJK5_HUMAN" 3 1036.5917 3.46 29080 12998 2 1036.591706 519.3031 Zyxin OS=Homo sapiens OX=9606 GN=ZYX PE=1 SV=1 8.47 2560.4 - 2.57E+06 - - - 0.0096 - 2.014 0.492 - 381.6 1 2 0 0 11 0 0 0 1.97E+08 5.69E+07 - - - 4.5689 0.9999 221125_WJC_METTL3_EV_vs_WT_F03.13000.13000.2 2.47E-05 20-Nov K.DVLVATDVASK[136.11].G sp|Q9UJV9|DDX41_HUMAN 1 1124.6169 0.66 29082 13000 2 1124.615658 563.3157 Probable ATP-dependent RNA helicase DDX41 OS=Homo sapiens OX=9606 GN=DDX41 PE=1 SV=2 4.21 2560.5 - 3.58E+06 - - - -1.0635 - 2.217 0.518 - 432.3 1 2 0 -0.0012 11 0 0 0 5.86E+07 8.84E+07 - - - 5.0204 1 221125_WJC_METTL3_EV_vs_WT_F03.13001.13001.3 1.85E-07 20/56 R.STSHK[136.11]PDEIYGMIER[166.11].L sp|Q86U44|MTA70_HUMAN 1 1779.8581 0.01 29083 13001 3 1779.854291 594.2933 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 5.42 2560.6 - 2.38E+06 - - - -2.1142 - 3.311 0.529 - 485.7 1 2 0 -0.0038 15 0 0 0 9.30E+05 7.45E+07 - - - 7.5609 0.9987 221125_WJC_METTL3_EV_vs_WT_F03.13003.13003.2 0.00833 16-Aug K.EIAEAYLGK.T "sp|P11142|HSP7C_HUMAN,tr|E9PQQ4|E9PQQ4_HUMAN,tr|E9PKE3|E9PKE3_HUMAN,tr|E9PN89|E9PN89_HUMAN,tr|E9PLF4|E9PLF4_HUMAN,tr|E9PI65|E9PI65_HUMAN,tr|E9PK54|E9PK54_HUMAN,tr|E9PPY6|E9PPY6_HUMAN,tr|E9PQK7|E9PQK7_HUMAN" 9 992.5179 0.16 29085 13003 2 992.51653 497.2662 Heat shock cognate 71 kDa protein OS=Homo sapiens OX=9606 GN=HSPA8 PE=1 SV=1 4.53 2560.7 - 1.95E+06 - - - -1.342 - 1.65 0.269 - 269.6 1 2 0 -0.0013 9 0 0 0 9.79E+07 5.98E+08 - - - 2.4762 0.9912 221125_WJC_METTL3_EV_vs_WT_F03.13004.13004.2 0.00329 16-Dec V.ISNHLILNK.L "sp|P43243|MATR3_HUMAN,tr|D6RE02|D6RE02_HUMAN,tr|B3KM87|B3KM87_HUMAN,tr|A8MXP9|A8MXP9_HUMAN,tr|D6R991|D6R991_HUMAN,tr|D6RBK5|D6RBK5_HUMAN,tr|A0A0R4J2E8|A0A0R4J2E8_HUMAN,tr|D6RIA2|D6RIA2_HUMAN,tr|H0Y8T4|H0Y8T4_HUMAN,tr|D6REM6|D6REM6_HUMAN,tr|D6RBI2|D6RBI2_HUMAN" 11 1050.6186 2.02 29086 13004 2 1050.618383 526.3166 Matrin-3 OS=Homo sapiens OX=9606 GN=MATR3 PE=1 SV=2 8.76 2560.8 - 1.26E+06 - - - -0.1866 - 2.439 0.392 - 520.6 1 1 0 -0.0002 9 0 0 0 2.59E+07 1.28E+07 - - - 4.5157 0.9864 221125_WJC_METTL3_EV_vs_WT_F03.13006.13006.2 0.195 14-Jun R.DYLIDGSR.G sp|P18206|VINC_HUMAN 1 937.4505 1.09 29088 13006 2 937.449111 469.7325 Vinculin OS=Homo sapiens OX=9606 GN=VCL PE=1 SV=4 4.21 2561.1 - 782660 - - - -1.4934 - 1.219 0.144 - 106.7 1 2 0 -0.0014 8 0 0 0 8.90E+08 8.16E+08 - - - 0.7014 0.9998 221125_WJC_METTL3_EV_vs_WT_F03.13008.13008.2 0.00124 22-Oct M.VYISNGQVLDSR.S "sp|Q9Y6D0|SELK_HUMAN,tr|F8WAX7|F8WAX7_HUMAN,tr|F6XHT0|F6XHT0_HUMAN" 3 1349.6939 0.68 29090 13008 2 1349.69278 675.8542 Selenoprotein K OS=Homo sapiens OX=9606 GN=SELENOK PE=1 SV=3 5.81 2561.3 - 452822 - - - -0.8513 - 1.886 0.468 - 338.9 1 2 0 -0.0011 12 0 0 0 9.46E+06 1.38E+07 - - - 4.1667 0.9918 221125_WJC_METTL3_EV_vs_WT_F03.13012.13012.4 0.0223 14/84 R.STSHK[136.11]PDEIYGMIER[166.11].L sp|Q86U44|MTA70_HUMAN 1 1779.8581 0.001 29092 13012 4 1779.852165 445.9718 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 5.42 2561.7 - 2.25E+06 - - - -3.3087 - 2.11 0.258 - 128 1 2 0 -0.0059 15 0 0 0 0.00E+00 4.88E+07 - - - 1.7372 0.9954 221125_WJC_METTL3_EV_vs_WT_F03.13013.13013.2 0.022 18-Jul R.YLTTAVITNK[136.11].D "sp|P60228|EIF3E_HUMAN,tr|A0A7I2V3I2|A0A7I2V3I2_HUMAN,tr|A0A7I2V5Z6|A0A7I2V5Z6_HUMAN,tr|A0A7I2V2H9|A0A7I2V2H9_HUMAN,tr|B3KW56|B3KW56_HUMAN,tr|A0A7I2V4B4|A0A7I2V4B4_HUMAN,tr|E5RGA2|E5RGA2_HUMAN,tr|A0A7I2V3I0|A0A7I2V3I0_HUMAN,tr|A0A7I2V3S3|A0A7I2V3S3_HUMAN,tr|E5RHS5|E5RHS5_HUMAN,tr|A0A7I2V2W0|A0A7I2V2W0_HUMAN,tr|A0A7I2V5P9|A0A7I2V5P9_HUMAN" 12 1130.6427 0.71 29093 13013 2 1130.643725 566.3286 Eukaryotic translation initiation factor 3 subunit E OS=Homo sapiens OX=9606 GN=EIF3E PE=1 SV=1 8.59 2561.8 - 2.04E+06 - - - 0.9287 - 1.291 0.215 - 114.3 1 2 0 0.001 10 0 0 0 2.92E+07 4.10E+07 - - - 1.3416 0.9999 221125_WJC_METTL3_EV_vs_WT_F03.13014.13014.2 0.00102 20-Oct R.SPGAPGPLTLK[136.11].E "sp|Q15942|ZYX_HUMAN,tr|H0Y2Y8|H0Y2Y8_HUMAN,tr|C9JJK5|C9JJK5_HUMAN" 3 1044.6059 3.46 29094 13014 2 1044.605564 523.3102 Zyxin OS=Homo sapiens OX=9606 GN=ZYX PE=1 SV=1 8.47 2561.9 - 2.01E+06 - - - -0.3178 - 2.045 0.48 - 384.9 1 2 0 -0.0003 11 0 0 0 1.97E+08 5.69E+07 - - - 4.5215 0.9994 221125_WJC_METTL3_EV_vs_WT_F03.13020.13020.2 0.148 16-Jul R.DLPNALDEK[136.11].Q sp|Q9NVJ2|ARL8B_HUMAN 1 1021.5171 1.4 29098 13020 2 1021.515795 511.7658 ADP-ribosylation factor-like protein 8B OS=Homo sapiens OX=9606 GN=ARL8B PE=1 SV=1 4.03 2562.6 - 4.30E+06 - - - -1.3167 - 1.486 0.396 - 130.8 1 2 0 -0.0013 9 0 0 0 1.08E+08 7.71E+07 - - - 3.1113 0.994 221125_WJC_METTL3_EV_vs_WT_F03.13021.13021.2 0.161 14-Jun K.EVDIYTVK.V "sp|Q99873|ANM1_HUMAN,sp|Q9NR22|ANM8_HUMAN,tr|E9PKG1|E9PKG1_HUMAN" 3 965.507 0.5 29099 13021 2 965.505422 483.7608 Protein arginine N-methyltransferase 1 OS=Homo sapiens OX=9606 GN=PRMT1 PE=1 SV=3 4.37 2562.6 - 2.30E+06 - - - -1.5961 - 1.236 0.224 - 121.7 1 2 0 -0.0015 8 0 0 0 4.90E+07 9.70E+07 - - - 1.334 0.9992 221125_WJC_METTL3_EV_vs_WT_F03.13022.13022.2 0.397 22-Oct R.AVLLAGPPGTGK[136.11].T "sp|Q9Y265|RUVB1_HUMAN,tr|E7ETR0|E7ETR0_HUMAN" 2 1087.6481 0.57 29100 13022 2 1087.647682 544.8313 RuvB-like 1 OS=Homo sapiens OX=9606 GN=RUVBL1 PE=1 SV=1 8.8 2562.7 - 1.67E+06 - - - -0.3797 - 2.047 0.222 - 257 1 2 0 -0.0004 12 0 0 0 3.03E+07 5.33E+07 - - - 2.5655 0.9994 221125_WJC_METTL3_EV_vs_WT_F03.13023.13023.2 0.0156 18-Jul K.MTISQQEFGR.T "sp|P55036|PSMD4_HUMAN,tr|H0Y3Y9|H0Y3Y9_HUMAN,tr|Q5VWC4|Q5VWC4_HUMAN" 3 1195.5656 1.33 29101 13023 2 1195.565549 598.7901 26S proteasome non-ATPase regulatory subunit 4 OS=Homo sapiens OX=9606 GN=PSMD4 PE=1 SV=1 5.75 2562.8 - 1.58E+06 - - - -0.0067 - 1.73 0.304 - 115.2 1 2 0 0 10 0 0 0 1.09E+08 8.22E+07 - - - 2.8163 0.9377 221125_WJC_METTL3_EV_vs_WT_F03.13024.13024.2 0.282 12-Aug F.VNDIFER[166.11].L "sp|Q8N257|H2B3B_HUMAN,sp|P33778|H2B1B_HUMAN,sp|Q5QNW6|H2B2F_HUMAN,sp|P58876|H2B1D_HUMAN,sp|Q99880|H2B1L_HUMAN,sp|P62807|H2B1C_HUMAN,sp|Q99877|H2B1N_HUMAN,sp|P57053|H2BFS_HUMAN,sp|P23527|H2B1O_HUMAN,sp|O60814|H2B1K_HUMAN,sp|Q93079|H2B1H_HUMAN,sp|Q99879|H2B1M_HUMAN,sp|Q16778|H2B2E_HUMAN,sp|P06899|H2B1J_HUMAN,tr|U3KQK0|U3KQK0_HUMAN" 15 901.4533 0.87 29102 13024 2 901.451449 451.7339 Histone H2B type 3-B OS=Homo sapiens OX=9606 GN=H2BU1 PE=1 SV=3 4.37 2562.9 - 1.47E+06 - - - -2.0545 - 1.829 0.282 - 244.4 1 1 0 -0.0019 7 0 0 0 2.45E+07 2.82E+07 - - - 3.0363 0.9153 221125_WJC_METTL3_EV_vs_WT_F03.13025.13025.2 0.00929 16-Jul M.LVYDITNEK[136.11].S "sp|P61006|RAB8A_HUMAN,sp|Q92930|RAB8B_HUMAN,tr|H0YNE9|H0YNE9_HUMAN" 3 1101.5797 0.85 29103 13025 2 1101.576734 551.7971 Ras-related protein Rab-8A OS=Homo sapiens OX=9606 GN=RAB8A PE=1 SV=1 4.37 2562.9 - 1.30E+06 - - - -2.7288 - 1.579 0.385 - 132.2 1 1 0 -0.003 9 0 0 0 1.83E+07 2.15E+07 - - - 3.2052 0.9824 221125_WJC_METTL3_EV_vs_WT_F03.13026.13026.2 0.419 14-Aug K.SVPENLLK[136.11].C "sp|Q13155|AIMP2_HUMAN,tr|A8MU58|A8MU58_HUMAN" 2 906.5266 0.8 29104 13026 2 906.52525 454.2706 Aminoacyl tRNA synthase complex-interacting multifunctional protein 2 OS=Homo sapiens OX=9606 GN=AIMP2 PE=1 SV=2 5.72 2563.1 - 742044 - - - -1.4704 - 1.263 0.105 - 167.9 1 2 0 -0.0013 8 0 0 0 2.52E+07 3.15E+07 - - - 0.5203 0.9998 221125_WJC_METTL3_EV_vs_WT_F03.13027.13027.2 2.24E-05 26-Dec R.VGGVQSLGGTGALR.L sp|P17174|AATC_HUMAN 1 1270.6993 1.77 29105 13027 2 1270.69721 636.357 "Aspartate aminotransferase, cytoplasmic OS=Homo sapiens OX=9606 GN=GOT1 PE=1 SV=3" 9.72 2563.2 - 543109 - - - -1.6833 - 2.562 0.513 - 528.5 1 2 0 -0.0021 14 0 0 0 8.81E+06 4.99E+06 - - - 5.1902 0.9995 221125_WJC_METTL3_EV_vs_WT_F03.13028.13028.2 0.000146 26-Dec K.LIETTANMNSSYVK.F "sp|P46100|ATRX_HUMAN,tr|A0A096LNN3|A0A096LNN3_HUMAN,tr|A0A096LNL9|A0A096LNL9_HUMAN,tr|A0A096LNW1|A0A096LNW1_HUMAN" 4 1569.7709 0.93 29106 13028 2 1569.774145 785.8927 Transcriptional regulator ATRX OS=Homo sapiens OX=9606 GN=ATRX PE=1 SV=5 6 2563.3 - 539939 - - - 2.0933 - 1.946 0.467 - 169.6 1 2 0 0.0033 14 0 0 0 4.26E+06 4.60E+06 - - - 4.16 0.9973 221125_WJC_METTL3_EV_vs_WT_F03.13034.13034.2 0.15 18-Sep K.QSLPPGLAVK.E sp|P63173|RL38_HUMAN 1 1008.5968 1.16 29110 13034 2 1008.595817 505.3057 60S ribosomal protein L38 OS=Homo sapiens OX=9606 GN=RPL38 PE=1 SV=2 8.75 2564.1 - 1.01E+06 - - - -0.9558 - 1.571 0.188 - 223.3 1 2 0 -0.001 10 0 0 0 7.66E+09 6.59E+09 - - - 1.6901 0.9999 221125_WJC_METTL3_EV_vs_WT_F03.13035.13035.2 2.01E-07 13/28 R.VSLAGAC[160.03]GVGGYGSR.S "sp|P13647|K2C5_HUMAN,tr|F8VV57|F8VV57_HUMAN" 2 1409.6721 999 29111 13035 2 1409.671768 705.8434 "Keratin, type II cytoskeletal 5 OS=Homo sapiens OX=9606 GN=KRT5 PE=1 SV=3" 8.19 2564.2 - 649160 - - - -0.2696 - 2.48 0.531 - 528.6 1 2 0 -0.0004 15 0 0 0 1.82E+08 0.00E+00 - - - 5.1958 0.9997 221125_WJC_METTL3_EV_vs_WT_F03.13036.13036.2 0.00954 24-Dec R.LAGAPSEDPQFPK.V sp|O00391|QSOX1_HUMAN 1 1355.6721 3.5 29112 13036 2 1355.674323 678.8433 Sulfhydryl oxidase 1 OS=Homo sapiens OX=9606 GN=QSOX1 PE=1 SV=3 4.37 2564.4 - 596800 - - - 1.6169 - 2.205 0.429 - 430.4 1 2 0 0.0022 13 0 0 0 9.20E+06 2.63E+06 - - - 4.2383 0.9558 221125_WJC_METTL3_EV_vs_WT_F03.13041.13041.2 0.375 16-Sep M.LVYDITNEK.S "sp|P61006|RAB8A_HUMAN,sp|Q92930|RAB8B_HUMAN,tr|H0YNE9|H0YNE9_HUMAN" 3 1093.5655 0.88 29116 13041 2 1093.565343 547.79 Ras-related protein Rab-8A OS=Homo sapiens OX=9606 GN=RAB8A PE=1 SV=1 4.37 2565 - 1.38E+06 - - - -0.1801 - 1.568 0.306 - 240.9 1 1 0 -0.0002 9 0 0 0 1.89E+07 2.15E+07 - - - 2.6024 0.9999 221125_WJC_METTL3_EV_vs_WT_F03.13043.13043.2 4.76E-09 20-Dec R.FDDAVVQSDMK[136.11].H "sp|P11142|HSP7C_HUMAN,tr|E9PQQ4|E9PQQ4_HUMAN,tr|E9PNE6|E9PNE6_HUMAN,tr|E9PKE3|E9PKE3_HUMAN,tr|E9PN89|E9PN89_HUMAN,tr|E9PLF4|E9PLF4_HUMAN,tr|E9PK54|E9PK54_HUMAN,tr|E9PN25|E9PN25_HUMAN,tr|E9PPY6|E9PPY6_HUMAN,tr|E9PQK7|E9PQK7_HUMAN" 10 1261.574 0.15 29117 13043 2 1261.574027 631.7943 Heat shock cognate 71 kDa protein OS=Homo sapiens OX=9606 GN=HSPA8 PE=1 SV=1 3.93 2565.2 - 1.87E+06 - - - 0.019 - 2.566 0.555 - 387.5 1 2 0 0 11 0 0 0 2.12E+08 1.44E+09 - - - 5.6895 0.9966 221125_WJC_METTL3_EV_vs_WT_F03.13045.13045.2 1.08 12-Aug K.STELLIR[166.11].K "sp|Q5TEC6|H3PS2_HUMAN,sp|Q16695|H31T_HUMAN,sp|P84243|H33_HUMAN,sp|Q6NXT2|H3C_HUMAN,sp|Q71DI3|H32_HUMAN,sp|P68431|H31_HUMAN,tr|B4DEB1|B4DEB1_HUMAN,tr|K7EK07|K7EK07_HUMAN,tr|K7ES00|K7ES00_HUMAN,tr|K7EP01|K7EP01_HUMAN,tr|K7EMV3|K7EMV3_HUMAN,tr|A0A590UJJ6|A0A590UJJ6_HUMAN" 12 840.4944 0.71 29119 13045 2 840.493938 421.2545 Histone HIST2H3PS2 OS=Homo sapiens OX=9606 GN=H3-2 PE=1 SV=1 5.72 2565.3 - 1.53E+06 - - - -0.5949 - 1.57 0.128 - 371.7 1 2 0 -0.0005 7 0 0 0 7.57E+07 1.07E+08 - - - 1.4155 1 221125_WJC_METTL3_EV_vs_WT_F03.13049.13049.2 2.35E-06 22-Dec R.IIQEVEENPDLR.K sp|P07199|CENPB_HUMAN 1 1453.7413 1.82 29123 13049 2 1453.740683 727.8779 Major centromere autoantigen B OS=Homo sapiens OX=9606 GN=CENPB PE=1 SV=2 4 2565.9 - 238256 - - - -0.4058 - 2.538 0.587 - 627.2 1 2 0 -0.0006 12 0 0 0 5.25E+06 2.88E+06 - - - 5.827 0.9998 221125_WJC_METTL3_EV_vs_WT_F03.13055.13055.2 0.000911 14-Sep R.NSLYDMAR.Y "sp|Q9BWF3|RBM4_HUMAN,sp|Q9BQ04|RBM4B_HUMAN,tr|E9PB51|E9PB51_HUMAN" 3 968.4386 1.38 29127 13055 2 968.438501 485.2266 RNA-binding protein 4 OS=Homo sapiens OX=9606 GN=RBM4 PE=1 SV=1 5.84 2566.7 - 7.67E+06 - - - -0.0671 - 1.994 0.413 - 502 1 2 0 -0.0001 8 0 0 0 8.52E+08 6.18E+08 - - - 4.1728 0.9995 221125_WJC_METTL3_EV_vs_WT_F03.13056.13056.2 0.0387 18-Oct K.QSLPPGLAVK[136.11].E sp|P63173|RL38_HUMAN 1 1016.611 1.16 29128 13056 2 1016.610783 509.3128 60S ribosomal protein L38 OS=Homo sapiens OX=9606 GN=RPL38 PE=1 SV=2 8.75 2566.7 - 6.94E+06 - - - -0.1948 - 1.705 0.344 - 335.7 1 2 0 -0.0002 10 0 0 0 7.66E+09 6.59E+09 - - - 3.0711 0.9998 221125_WJC_METTL3_EV_vs_WT_F03.13057.13057.2 0.00169 14-Oct R.NSLYDMAR[166.11].Y "sp|Q9BWF3|RBM4_HUMAN,sp|Q9BQ04|RBM4B_HUMAN,tr|E9PB51|E9PB51_HUMAN" 3 978.4468 1.38 29129 13057 2 978.447149 490.2307 RNA-binding protein 4 OS=Homo sapiens OX=9606 GN=RBM4 PE=1 SV=1 5.84 2566.7 - 7.35E+06 - - - 0.3199 - 2.008 0.424 - 644.3 1 2 0 0.0003 8 0 0 0 8.52E+08 6.18E+08 - - - 4.2751 0.9998 221125_WJC_METTL3_EV_vs_WT_F03.13058.13058.2 6.15E-05 20-Dec K.EYNALVAQGVR[166.11].V "sp|Q9H7C9|AAMDC_HUMAN,tr|E9PNP3|E9PNP3_HUMAN,tr|E9PR47|E9PR47_HUMAN,tr|E9PIQ4|E9PIQ4_HUMAN" 4 1228.644 1.86 29130 13058 2 1228.644626 615.3293 Mth938 domain-containing protein OS=Homo sapiens OX=9606 GN=AAMDC PE=1 SV=1 6.1 2566.8 - 5.59E+06 - - - 0.5453 - 1.965 0.426 - 680.3 1 2 0 0.0007 11 0 0 0 3.77E+08 2.02E+08 - - - 4.0146 0.9917 221125_WJC_METTL3_EV_vs_WT_F03.13059.13059.2 0.718 12-Jul K.STELLIR.K "sp|Q5TEC6|H3PS2_HUMAN,sp|Q16695|H31T_HUMAN,sp|P84243|H33_HUMAN,sp|Q6NXT2|H3C_HUMAN,sp|Q71DI3|H32_HUMAN,sp|P68431|H31_HUMAN,tr|B4DEB1|B4DEB1_HUMAN,tr|K7EK07|K7EK07_HUMAN,tr|K7ES00|K7ES00_HUMAN,tr|K7EP01|K7EP01_HUMAN,tr|K7EMV3|K7EMV3_HUMAN,tr|A0A590UJJ6|A0A590UJJ6_HUMAN" 12 830.4862 0.68 29131 13059 2 830.486336 416.2504 Histone HIST2H3PS2 OS=Homo sapiens OX=9606 GN=H3-2 PE=1 SV=1 5.72 2566.8 - 2.09E+06 - - - 0.2023 - 1.431 0.079 - 319.6 1 2 0 0.0002 7 0 0 0 7.10E+07 1.05E+08 - - - 0.76 0.9994 221125_WJC_METTL3_EV_vs_WT_F03.13060.13060.2 0.0191 20-Oct K.EYLLGSTAEEK[136.11].A "sp|O43324|MCA3_HUMAN,tr|C9J1V9|C9J1V9_HUMAN,tr|H0YAL7|H0YAL7_HUMAN,tr|D6RBD7|D6RBD7_HUMAN,tr|D6RCQ0|D6RCQ0_HUMAN" 5 1246.6172 1.1 29132 13060 2 1246.618343 624.3159 Eukaryotic translation elongation factor 1 epsilon-1 OS=Homo sapiens OX=9606 GN=EEF1E1 PE=1 SV=1 4.25 2566.9 - 1.30E+06 - - - 0.8784 - 1.743 0.336 - 365.8 1 2 0 0.0011 11 0 0 0 3.89E+07 3.54E+07 - - - 3.0254 1 221125_WJC_METTL3_EV_vs_WT_F03.13061.13061.2 2.25E-09 14/24 R.SMVAVMDSDTTGK.L "sp|P04632|CPNS1_HUMAN,tr|A0A075B7C0|A0A075B7C0_HUMAN,tr|A0A0C4DGQ5|A0A0C4DGQ5_HUMAN,tr|U3KPR7|U3KPR7_HUMAN,tr|U3KQE2|U3KQE2_HUMAN,tr|K7EIV0|K7EIV0_HUMAN,tr|K7EKD8|K7EKD8_HUMAN,tr|K7EM73|K7EM73_HUMAN" 8 1340.5952 1.47 29133 13061 2 1340.596569 671.3049 Calpain small subunit 1 OS=Homo sapiens OX=9606 GN=CAPNS1 PE=1 SV=1 4.21 2567 - 1.02E+06 - - - 1.0197 - 2.637 0.618 - 684 1 2 0 0.0014 13 0 0 0 1.81E+07 1.23E+07 - - - 6.0937 1 221125_WJC_METTL3_EV_vs_WT_F03.13062.13062.2 1.35E-08 14/24 R.SMVAVMDSDTTGK[136.11].L "sp|P04632|CPNS1_HUMAN,tr|A0A075B7C0|A0A075B7C0_HUMAN,tr|A0A0C4DGQ5|A0A0C4DGQ5_HUMAN,tr|U3KPR7|U3KPR7_HUMAN,tr|U3KQE2|U3KQE2_HUMAN,tr|K7EIV0|K7EIV0_HUMAN,tr|K7EKD8|K7EKD8_HUMAN,tr|K7EM73|K7EM73_HUMAN" 8 1348.6094 1.47 29134 13062 2 1348.609211 675.312 Calpain small subunit 1 OS=Homo sapiens OX=9606 GN=CAPNS1 PE=1 SV=1 4.21 2567.2 - 774356 - - - -0.1416 - 2.961 0.667 - 737.4 1 2 0 -0.0002 13 0 0 0 1.81E+07 1.23E+07 - - - 6.7534 0.9997 221125_WJC_METTL3_EV_vs_WT_F03.13064.13064.2 0.000262 22-Nov R.EGIVTATEQEVK[136.11].E "sp|Q12931|TRAP1_HUMAN,tr|I3L0K7|I3L0K7_HUMAN" 2 1310.6809 3.25 29136 13064 2 1310.678831 656.3477 "Heat shock protein 75 kDa, mitochondrial OS=Homo sapiens OX=9606 GN=TRAP1 PE=1 SV=3" 4.25 2567.4 - 707570 - - - -1.587 - 2.108 0.412 - 436.8 1 2 0 -0.0021 12 0 0 0 3.38E+07 1.04E+07 - - - 4.0455 0.9992 221125_WJC_METTL3_EV_vs_WT_F03.13066.13066.2 0.0208 16-Jul R.LDPFADGGK.T sp|O75533|SF3B1_HUMAN 1 918.4447 1.19 29138 13066 2 918.444536 460.2296 Splicing factor 3B subunit 1 OS=Homo sapiens OX=9606 GN=SF3B1 PE=1 SV=3 4.21 2567.7 - 617021 - - - -0.1753 - 1.443 0.332 - 135.5 1 2 0 -0.0002 9 0 0 0 8.22E+06 6.90E+06 - - - 2.5541 0.9992 221125_WJC_METTL3_EV_vs_WT_F03.13067.13067.2 0.0411 14-Aug R.LLEFNQGK[136.11].L "sp|P41250|GARS_HUMAN,tr|H7C443|H7C443_HUMAN,tr|A0A6Q8PGI6|A0A6Q8PGI6_HUMAN,tr|A0A6Q8PGA8|A0A6Q8PGA8_HUMAN,tr|A0A6Q8PGW4|A0A6Q8PGW4_HUMAN,tr|A0A6Q8PGZ8|A0A6Q8PGZ8_HUMAN,tr|A0A6Q8PH49|A0A6Q8PH49_HUMAN,tr|A0A6Q8PHH9|A0A6Q8PHH9_HUMAN,tr|A0A6Q8PF45|A0A6Q8PF45_HUMAN,tr|A0A6Q8PHI7|A0A6Q8PHI7_HUMAN,tr|A0A6Q8PFZ6|A0A6Q8PFZ6_HUMAN" 11 955.5218 1.46 29139 13067 2 955.520717 478.7682 Glycine--tRNA ligase OS=Homo sapiens OX=9606 GN=GARS1 PE=1 SV=3 6 2567.8 - 565484 - - - -1.1669 - 1.498 0.348 - 148 1 2 0 -0.0011 8 0 0 0 6.80E+07 4.65E+07 - - - 2.8298 1 221125_WJC_METTL3_EV_vs_WT_F03.13068.13068.2 4.63E-09 24-Dec K.EYLEAEENGDLER.M "sp|Q96DF8|ESS2_HUMAN,tr|F8WEF8|F8WEF8_HUMAN" 2 1565.6845 2.4 29140 13068 2 1565.685124 783.8495 Splicing factor ESS-2 homolog OS=Homo sapiens OX=9606 GN=ESS2 PE=1 SV=1 3.83 2568 - 473823 - - - 0.3692 - 2.561 0.664 - 547.1 1 2 0 0.0006 13 0 0 0 6.93E+06 2.88E+06 - - - 6.3587 1 221125_WJC_METTL3_EV_vs_WT_F03.13072.13072.2 2.23E-08 13/20 R.FDDAVVQSDMK.H "sp|P11142|HSP7C_HUMAN,tr|E9PQQ4|E9PQQ4_HUMAN,tr|E9PNE6|E9PNE6_HUMAN,tr|E9PKE3|E9PKE3_HUMAN,tr|E9PN89|E9PN89_HUMAN,tr|E9PLF4|E9PLF4_HUMAN,tr|E9PK54|E9PK54_HUMAN,tr|E9PN25|E9PN25_HUMAN,tr|E9PPY6|E9PPY6_HUMAN,tr|E9PQK7|E9PQK7_HUMAN" 10 1253.5598 0.15 29142 13072 2 1253.559383 627.7872 Heat shock cognate 71 kDa protein OS=Homo sapiens OX=9606 GN=HSPA8 PE=1 SV=1 3.93 2568.5 - 3.09E+06 - - - -0.335 - 2.8 0.592 - 493.6 1 2 0 -0.0004 11 0 0 0 2.12E+08 1.44E+09 - - - 6.1987 0.9995 221125_WJC_METTL3_EV_vs_WT_F03.13073.13073.2 0.000345 18-Oct R.FTVLTESAAK.N sp|P07196|NFL_HUMAN 1 1065.5706 1.47 29143 13073 2 1065.567792 533.7926 Neurofilament light polypeptide OS=Homo sapiens OX=9606 GN=NEFL PE=1 SV=3 6 2568.5 - 1.90E+06 - - - -2.6596 - 1.947 0.506 - 335.8 1 2 0 -0.0028 10 0 0 0 1.34E+08 9.08E+07 - - - 4.6372 0.9856 221125_WJC_METTL3_EV_vs_WT_F03.13074.13074.2 0.000302 20-Sep N.AGVEGSLIVEK[136.11].L "sp|P10809|CH60_HUMAN,tr|A0A7I2V2X6|A0A7I2V2X6_HUMAN,tr|A0A7I2YQK6|A0A7I2YQK6_HUMAN,tr|A0A7I2V599|A0A7I2V599_HUMAN" 4 1108.6219 1.5 29144 13074 2 1108.621504 555.3182 "60 kDa heat shock protein, mitochondrial OS=Homo sapiens OX=9606 GN=HSPD1 PE=1 SV=2" 4.53 2568.7 - 685590 - - - -0.3933 - 2.186 0.364 - 255 1 1 0 -0.0004 11 0 0 0 5.61E+07 3.73E+07 - - - 3.8451 0.9966 221125_WJC_METTL3_EV_vs_WT_F03.13077.13077.2 0.00497 24-Oct K.SVPLATAPMAEQR[166.11].T sp|Q9Y678|COPG1_HUMAN 1 1379.7107 1.78 29147 13077 2 1379.706152 690.8626 Coatomer subunit gamma-1 OS=Homo sapiens OX=9606 GN=COPG1 PE=1 SV=1 5.72 2569 - 359333 - - - -3.2637 - 1.811 0.301 - 219.2 1 2 0 -0.0045 13 0 0 0 1.34E+07 7.52E+06 - - - 2.787 0.998 221125_WJC_METTL3_EV_vs_WT_F03.13078.13078.3 0.0148 Nov-40 K.EYNALVAQGVR[166.11].V "sp|Q9H7C9|AAMDC_HUMAN,tr|E9PNP3|E9PNP3_HUMAN,tr|E9PR47|E9PR47_HUMAN,tr|E9PIQ4|E9PIQ4_HUMAN" 4 1228.644 2.29 29148 13078 3 1228.64635 410.5553 Mth938 domain-containing protein OS=Homo sapiens OX=9606 GN=AAMDC PE=1 SV=1 6.1 2569.1 - 334283 - - - 1.9485 - 1.725 0.284 - 173.5 1 2 0 0.0024 11 0 0 0 1.99E+07 8.71E+06 - - - 3.2546 0.8731 221125_WJC_METTL3_EV_vs_WT_F03.13079.13079.2 0.00443 30-Aug R.YAQPATATAATAAAAA.A "sp|O43251|RFOX2_HUMAN,tr|B0QYV1|B0QYV1_HUMAN,tr|A0A0G2JRD1|A0A0G2JRD1_HUMAN,tr|A0A0G2JRA5|A0A0G2JRA5_HUMAN,tr|S4R3K7|S4R3K7_HUMAN" 5 1419.6994 - 29149 13079 2 1419.698446 710.857 RNA binding protein fox-1 homolog 2 OS=Homo sapiens OX=9606 GN=RBFOX2 PE=1 SV=3 5.52 2569.3 - 290647 - - - -0.6776 - 1.467 0.232 - 124.9 1 1 0 -0.001 16 0 0 0 - - - - - 1.6964 0.9989 221125_WJC_METTL3_EV_vs_WT_F03.13080.13080.2 0.000657 22-Dec R.IIQEVEENPDLR[166.11].K sp|P07199|CENPB_HUMAN 1 1463.7495 1.82 29150 13080 2 1463.74366 732.882 Major centromere autoantigen B OS=Homo sapiens OX=9606 GN=CENPB PE=1 SV=2 4 2569.4 - 253979 - - - -4.0191 - 2.443 0.477 - 549.4 1 2 0 -0.0059 12 0 0 0 5.25E+06 2.88E+06 - - - 4.9125 0.9723 221125_WJC_METTL3_EV_vs_WT_F03.13083.13083.2 2.31 22-Jul R.R[166.11]DTETSQQALGK.R sp|Q8WTQ4|CP078_HUMAN 1 1342.6716 - 29151 13083 2 1342.671808 672.3431 Uncharacterized protein C16orf78 OS=Homo sapiens OX=9606 GN=C16orf78 PE=2 SV=1 6.07 2569.8 - 1.73E+06 - - - 0.1348 - 1.171 0.067 - 137.2 1 2 0 0.0002 12 0 0 0 - - - - - -0.0488 0.9754 221125_WJC_METTL3_EV_vs_WT_F03.13084.13084.2 0.194 24-Jul K.SVPLATAPMAEQR.T sp|Q9Y678|COPG1_HUMAN 1 1369.7024 1.78 29152 13084 2 1369.699344 685.8585 Coatomer subunit gamma-1 OS=Homo sapiens OX=9606 GN=COPG1 PE=1 SV=1 5.72 2569.9 - 596770 - - - -2.2202 - 1.376 0.104 - 126.6 1 2 0 -0.003 13 0 0 0 1.34E+07 7.52E+06 - - - 0.6274 0.9999 221125_WJC_METTL3_EV_vs_WT_F03.13085.13085.2 6.47E-05 18-Nov K.SSDTLAMDMR.V sp|Q5JSZ5|PRC2B_HUMAN 1 1125.4794 1.55 29153 13085 2 1125.479306 563.747 Protein PRRC2B OS=Homo sapiens OX=9606 GN=PRRC2B PE=1 SV=2 4.21 2570 - 2.18E+06 - - - -0.1226 - 2.206 0.572 - 511.3 1 2 0 -0.0001 10 0 0 0 5.71E+07 3.69E+07 - - - 5.4742 0.9989 221125_WJC_METTL3_EV_vs_WT_F03.13086.13086.2 0.285 16-Sep R.GQVFDVGPR[166.11].Y sp|P28482|MK01_HUMAN 1 983.5064 0.61 29154 13086 2 983.506578 492.7605 Mitogen-activated protein kinase 1 OS=Homo sapiens OX=9606 GN=MAPK1 PE=1 SV=3 5.84 2570 - 2.62E+06 - - - 0.181 - 1.55 0.267 - 386.7 1 2 0 0.0002 9 0 0 0 2.02E+07 3.34E+07 - - - 2.2809 0.9999 221125_WJC_METTL3_EV_vs_WT_F03.13087.13087.3 0.019 Oct-36 K.LEDPHVDIIR[166.11].R sp|Q9BTV4|TMM43_HUMAN 1 1215.6487 0.4 29155 13087 3 1215.648255 406.2235 Transmembrane protein 43 OS=Homo sapiens OX=9606 GN=TMEM43 PE=1 SV=1 4.54 2570.1 - 1.32E+06 - - - -0.3718 - 2.113 0.371 - 153.1 1 2 0 -0.0005 10 0 0 0 5.28E+07 1.32E+08 - - - 4.861 0.9999 221125_WJC_METTL3_EV_vs_WT_F03.13092.13092.2 2.02E-07 24-Sep K.EYLEAEENGDLER[166.11].M "sp|Q96DF8|ESS2_HUMAN,tr|F8WEF8|F8WEF8_HUMAN" 2 1575.6928 2.4 29160 13092 2 1575.693437 788.8537 Splicing factor ESS-2 homolog OS=Homo sapiens OX=9606 GN=ESS2 PE=1 SV=1 3.83 2570.7 - 259776 - - - 0.3941 - 2.029 0.651 - 215.9 1 2 0 0.0006 13 0 0 0 6.93E+06 2.88E+06 - - - 5.665 0.9999 221125_WJC_METTL3_EV_vs_WT_F03.13094.13094.2 0.000722 20-Dec K.LSAMMGAVAEK[136.11].K "sp|Q86U44|MTA70_HUMAN,tr|F5H6D8|F5H6D8_HUMAN,tr|H0YFV6|H0YFV6_HUMAN,tr|B4DTN4|B4DTN4_HUMAN" 4 1114.5606 0.1 29161 13094 2 1114.560535 558.2876 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 6 2571 - 5.48E+06 - - - -0.0601 - 2.511 0.464 - 439.8 1 2 0 -0.0001 11 0 0 0 2.25E+07 2.28E+08 - - - 4.9587 0.8854 221125_WJC_METTL3_EV_vs_WT_F03.13096.13096.2 0.17 20-Jul R.TQSSASLAASY.A sp|Q96PK6|RBM14_HUMAN 1 1084.5037 - 29162 13096 2 1084.502338 543.2591 RNA-binding protein 14 OS=Homo sapiens OX=9606 GN=RBM14 PE=1 SV=2 5.18 2571.2 - 2.49E+06 - - - -1.2264 - 1.2 0.329 - 154.1 1 1 0 -0.0013 11 0 0 0 - - - - - 1.9638 0.9127 221125_WJC_METTL3_EV_vs_WT_F03.13098.13098.2 0.161 12-Aug R.K[136.11]IELFGR[166.11].P sp|Q86U44|MTA70_HUMAN 1 879.5297 0.01 29164 13098 2 879.528878 440.7721 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 8.75 2571.3 - 4.65E+06 - - - -0.9437 - 1.808 0.161 - 256.5 1 1 0 -0.0008 7 0 0 0 8.47E+07 1.29E+10 - - - 2.1064 0.9703 221125_WJC_METTL3_EV_vs_WT_F03.13099.13099.2 0.0836 12-Jul K.DGSC[160.03]LFR.A sp|Q01804|OTUD4_HUMAN 1 853.3752 1.68 29165 13099 2 853.372592 427.6949 OTU domain-containing protein 4 OS=Homo sapiens OX=9606 GN=OTUD4 PE=1 SV=4 5.83 2571.4 - 1.49E+06 - - - -3.0995 - 1.286 0.149 - 243.9 1 2 0 -0.0026 7 0 0 0 2.10E+07 1.25E+07 - - - 0.9377 0.9984 221125_WJC_METTL3_EV_vs_WT_F03.13100.13100.2 0.0459 22-Nov R.AVLLAGPPGTGK.T "sp|Q9Y265|RUVB1_HUMAN,tr|E7ETR0|E7ETR0_HUMAN" 2 1079.6339 0.57 29166 13100 2 1079.635208 540.8242 RuvB-like 1 OS=Homo sapiens OX=9606 GN=RUVBL1 PE=1 SV=1 8.8 2571.4 - 1.11E+06 - - - 1.2162 - 1.975 0.196 - 371.8 1 2 0 0.0013 12 0 0 0 3.03E+07 5.33E+07 - - - 2.2789 0.9998 221125_WJC_METTL3_EV_vs_WT_F03.13101.13101.3 7.80E-06 14/44 K.GFTAAGVLAAHK[136.11].L "sp|P32322|P5CR1_HUMAN,tr|J3QLK9|J3QLK9_HUMAN,tr|J3QL24|J3QL24_HUMAN,tr|E2QRB3|E2QRB3_HUMAN,tr|J3QRZ0|J3QRZ0_HUMAN,tr|J3QL23|J3QL23_HUMAN,tr|J3QR88|J3QR88_HUMAN,tr|J3KQ22|J3KQ22_HUMAN,tr|J3QL32|J3QL32_HUMAN,tr|J3QKT3|J3QKT3_HUMAN,tr|J3KTA8|J3KTA8_HUMAN" 11 1149.6386 1.21 29167 13101 3 1149.636453 384.2201 "Pyrroline-5-carboxylate reductase 1, mitochondrial OS=Homo sapiens OX=9606 GN=PYCR1 PE=1 SV=2" 8.76 2571.6 - 647320 - - - -1.8615 - 2.241 0.403 - 171.9 1 2 0 -0.0021 12 0 0 0 2.13E+07 1.75E+07 - - - 5.2691 0.9213 221125_WJC_METTL3_EV_vs_WT_F03.13103.13103.2 3.17 12-Jun K.NNFFVEK.N "sp|Q53GS9|SNUT2_HUMAN,tr|B9A018|B9A018_HUMAN,tr|A0A087X1B2|A0A087X1B2_HUMAN" 3 896.4392 0.77 29169 13103 2 896.438896 449.2269 U4\U6.U5 tri-snRNP-associated protein 2 OS=Homo sapiens OX=9606 GN=USP39 PE=1 SV=2 6 2571.8 - 326334 - - - -0.3592 - 1.075 0.018 - 98.5 2 2 0 -0.0003 7 0 0 0 4.25E+06 5.51E+06 - - - -0.7315 0.8529 221125_WJC_METTL3_EV_vs_WT_F03.13107.13107.2 0.115 16-Aug R.YPDGIISK[136.11]P.K sp|Q86U44|MTA70_HUMAN 1 996.5371 0.04 29171 13107 2 996.536915 499.2758 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 5.83 2572.3 - 4.16E+06 - - - -0.2328 - 1.302 0.231 - 159.8 1 1 0 -0.0002 9 0 0 0 5.82E+06 1.32E+08 - - - 1.5106 0.9984 221125_WJC_METTL3_EV_vs_WT_F03.13108.13108.2 0.0858 20-Aug K.EYLLGSTAEEK.A "sp|O43324|MCA3_HUMAN,tr|C9J1V9|C9J1V9_HUMAN,tr|H0YAL7|H0YAL7_HUMAN,tr|D6RBD7|D6RBD7_HUMAN,tr|D6RCQ0|D6RCQ0_HUMAN" 5 1238.603 1.1 29172 13108 2 1238.602717 620.3088 Eukaryotic translation elongation factor 1 epsilon-1 OS=Homo sapiens OX=9606 GN=EEF1E1 PE=1 SV=1 4.25 2572.3 - 2.69E+06 - - - -0.2672 - 1.591 0.223 - 194.8 1 2 0 -0.0003 11 0 0 0 3.89E+07 3.54E+07 - - - 1.9442 0.9988 221125_WJC_METTL3_EV_vs_WT_F03.13111.13111.2 0.00369 16-Aug K.NVSIGIVGK[136.11].D "sp|P25786|PSA1_HUMAN,tr|F5GX11|F5GX11_HUMAN" 2 893.5426 0.82 29175 13111 2 893.541514 447.7786 Proteasome subunit alpha type-1 OS=Homo sapiens OX=9606 GN=PSMA1 PE=1 SV=1 8.75 2572.6 - 1.20E+06 - - - -1.1785 - 1.46 0.314 - 187.2 1 2 0 -0.0011 9 0 0 0 1.21E+08 1.48E+08 - - - 2.4547 0.9998 221125_WJC_METTL3_EV_vs_WT_F03.13117.13117.2 3.50E-05 22-Dec K.NAGVEGSLIVEK.L "sp|P10809|CH60_HUMAN,tr|A0A7I2V2X6|A0A7I2V2X6_HUMAN,tr|A0A7I2YQK6|A0A7I2YQK6_HUMAN,tr|A0A7I2V599|A0A7I2V599_HUMAN" 4 1214.6507 1.33 29179 13117 2 1214.649792 608.3326 "60 kDa heat shock protein, mitochondrial OS=Homo sapiens OX=9606 GN=HSPD1 PE=1 SV=2" 4.53 2573.3 - 3.28E+07 - - - -0.7204 - 2.363 0.442 - 492.4 1 2 0 -0.0009 12 0 0 0 2.71E+10 2.04E+10 - - - 4.568 0.9999 221125_WJC_METTL3_EV_vs_WT_F03.13118.13118.2 0.000537 13/22 K.NAGVEGSLIVEK[136.11].L "sp|P10809|CH60_HUMAN,tr|A0A7I2V2X6|A0A7I2V2X6_HUMAN,tr|A0A7I2YQK6|A0A7I2YQK6_HUMAN,tr|A0A7I2V599|A0A7I2V599_HUMAN" 4 1222.6649 1.33 29180 13118 2 1222.663612 612.3397 "60 kDa heat shock protein, mitochondrial OS=Homo sapiens OX=9606 GN=HSPD1 PE=1 SV=2" 4.53 2573.4 - 3.17E+07 - - - -1.0264 - 2.513 0.482 - 525.4 1 2 0 -0.0013 12 0 0 0 2.71E+10 2.04E+10 - - - 5.0252 0.9007 221125_WJC_METTL3_EV_vs_WT_F03.13120.13120.2 0.0572 16-Aug K.NVSIGIVGK.D "sp|P25786|PSA1_HUMAN,tr|F5GX11|F5GX11_HUMAN" 2 885.5284 0.83 29182 13120 2 885.523916 443.7715 Proteasome subunit alpha type-1 OS=Homo sapiens OX=9606 GN=PSMA1 PE=1 SV=1 8.75 2573.5 - 1.32E+06 - - - -5.0264 - 1.244 0.183 - 180.4 1 2 0 -0.0045 9 0 0 0 1.24E+08 1.48E+08 - - - 1.0229 0.9999 221125_WJC_METTL3_EV_vs_WT_F03.13121.13121.2 0.000237 14/22 K.IDVSIEAASGGK.A "sp|P09622|DLDH_HUMAN,tr|E9PEX6|E9PEX6_HUMAN" 2 1145.5928 2.94 29183 13121 2 1145.591552 573.8037 "Dihydrolipoyl dehydrogenase, mitochondrial OS=Homo sapiens OX=9606 GN=DLD PE=1 SV=2" 4.37 2573.6 - 1.19E+06 - - - -1.1051 - 2.504 0.549 - 567.8 1 2 0 -0.0013 12 0 0 0 1.68E+07 5.71E+06 - - - 5.5106 0.9936 221125_WJC_METTL3_EV_vs_WT_F03.13128.13128.2 0.0713 12-Jun K.VVDPFSK.K "sp|P61247|RS3A_HUMAN,tr|H0Y8L7|H0Y8L7_HUMAN,tr|D6RI02|D6RI02_HUMAN,tr|H0Y9Y4|H0Y9Y4_HUMAN,tr|E9PFI5|E9PFI5_HUMAN" 5 790.4225 1.14 29188 13128 2 790.420343 396.2185 40S ribosomal protein S3a OS=Homo sapiens OX=9606 GN=RPS3A PE=1 SV=2 5.81 2574.5 - 736986 - - - -2.7352 - 1.264 0.287 - 136.2 1 2 0 -0.0022 7 0 0 0 2.20E+07 1.93E+07 - - - 1.9024 0.9999 221125_WJC_METTL3_EV_vs_WT_F03.13132.13132.2 1.05E-05 20-Dec R.QGVDADINGLR.Q "sp|P35527|K1C9_HUMAN,tr|K7EQQ3|K7EQQ3_HUMAN" 2 1156.5837 728.62 29190 13132 2 1156.583933 579.2991 "Keratin, type I cytoskeletal 9 OS=Homo sapiens OX=9606 GN=KRT9 PE=1 SV=3" 4.21 2575 - 1.25E+06 - - - 0.2447 - 2.402 0.554 - 625.8 1 2 0 0.0003 11 0 0 0 2.15E+10 2.95E+07 - - - 5.5034 0.9997 221125_WJC_METTL3_EV_vs_WT_F03.13134.13134.2 0.0014 18-Sep K.STVVPVPYEK.M "sp|P78347|GTF2I_HUMAN,tr|A0A494C1K3|A0A494C1K3_HUMAN" 2 1117.6019 1.62 29192 13134 2 1117.601668 559.8082 General transcription factor II-I OS=Homo sapiens OX=9606 GN=GTF2I PE=1 SV=2 5.72 2575.1 - 5.34E+06 - - - -0.2309 - 1.836 0.391 - 280.1 1 2 0 -0.0003 10 0 0 0 4.30E+09 2.66E+09 - - - 3.6248 0.9699 221125_WJC_METTL3_EV_vs_WT_F03.13135.13135.2 0.00892 20-Jun R.NFIAQGPYENR.T sp|P21281|VATB2_HUMAN 1 1307.6258 3.18 29193 13135 2 1307.632918 654.8202 "V-type proton ATPase subunit B, brain isoform OS=Homo sapiens OX=9606 GN=ATP6V1B2 PE=1 SV=3" 6 2575.3 - 545521 - - - 5.406 - 1.515 0.298 - 48.9 2 2 0 0.0071 11 0 0 0 2.76E+07 8.66E+06 - - - 2.2291 0.9867 221125_WJC_METTL3_EV_vs_WT_F03.13136.13136.2 0.463 16-Aug R.NYLQSLPSK.T "sp|P27361|MK03_HUMAN,tr|H0YEX6|H0YEX6_HUMAN,tr|B3KR49|B3KR49_HUMAN,tr|E9PQW4|E9PQW4_HUMAN,tr|E9PRH7|E9PRH7_HUMAN,tr|E9PJF0|E9PJF0_HUMAN,tr|E9PBK7|E9PBK7_HUMAN" 7 1048.5553 0.1 29194 13136 2 1048.554617 525.2849 Mitogen-activated protein kinase 3 OS=Homo sapiens OX=9606 GN=MAPK3 PE=1 SV=4 8.59 2575.4 - 537597 - - - -0.6609 - 1.332 0.081 - 217.9 1 2 0 -0.0007 9 0 0 0 1.31E+07 1.36E+08 - - - 0.4684 0.9996 221125_WJC_METTL3_EV_vs_WT_F03.13142.13142.3 0.00914 Nov-44 K.NAGVEGSLIVEK[136.11].L "sp|P10809|CH60_HUMAN,tr|A0A7I2V2X6|A0A7I2V2X6_HUMAN,tr|A0A7I2YQK6|A0A7I2YQK6_HUMAN,tr|A0A7I2V599|A0A7I2V599_HUMAN" 4 1222.6649 1.45 29198 13142 3 1222.661878 408.5622 "60 kDa heat shock protein, mitochondrial OS=Homo sapiens OX=9606 GN=HSPD1 PE=1 SV=2" 4.53 2576.1 - 2.33E+06 - - - -2.4447 - 2.337 0.345 - 139.8 1 2 0 -0.003 12 0 0 0 1.71E+08 1.18E+08 - - - 4.7385 0.9876 221125_WJC_METTL3_EV_vs_WT_F03.13143.13143.2 0.0484 18-Oct K.SFTSEDDLVK[136.11].L sp|O00203|AP3B1_HUMAN 1 1147.5488 0.39 29199 13143 2 1147.542974 574.7817 AP-3 complex subunit beta-1 OS=Homo sapiens OX=9606 GN=AP3B1 PE=1 SV=3 4.03 2576.2 - 1.06E+06 - - - -5.1065 - 1.546 0.349 - 213.5 1 2 0 -0.0059 10 0 0 0 6.84E+06 1.75E+07 - - - 2.833 0.994 221125_WJC_METTL3_EV_vs_WT_F03.13144.13144.3 0.103 Dec-36 K.VLSNR[166.11]PIMFR[166.11].G "sp|Q13283|G3BP1_HUMAN,tr|A0A7I2YQF2|A0A7I2YQF2_HUMAN,tr|A0A7I2V5M7|A0A7I2V5M7_HUMAN,tr|A0A7I2YQH0|A0A7I2YQH0_HUMAN" 4 1251.7025 0.92 29200 13144 3 1251.702306 418.2414 Ras GTPase-activating protein-binding protein 1 OS=Homo sapiens OX=9606 GN=G3BP1 PE=1 SV=1 12 2576.4 - 972152 - - - -0.1446 - 1.875 0.156 - 261.7 1 2 0 -0.0002 10 0 0 0 3.06E+07 3.33E+07 - - - 2.115 0.9978 221125_WJC_METTL3_EV_vs_WT_F03.13147.13147.2 0.00645 13/18 R.SPEVLLGSAR.Y "sp|P06493|CDK1_HUMAN,tr|E5RIU6|E5RIU6_HUMAN,tr|A0A024QZP7|A0A024QZP7_HUMAN,tr|A0A087WZZ9|A0A087WZZ9_HUMAN" 4 1027.5662 0.12 29203 13147 2 1027.570337 514.7904 Cyclin-dependent kinase 1 OS=Homo sapiens OX=9606 GN=CDK1 PE=1 SV=3 5.72 2576.7 - 1.17E+06 - - - 4.0173 - 2.246 0.356 - 495.3 1 2 0 0.0041 10 0 0 0 4.55E+07 3.86E+08 - - - 3.9277 0.9774 221125_WJC_METTL3_EV_vs_WT_F03.13149.13149.3 0.225 Oct-36 K.VLSNRPIMFR.G "sp|Q13283|G3BP1_HUMAN,tr|A0A7I2YQF2|A0A7I2YQF2_HUMAN,tr|A0A7I2V5M7|A0A7I2V5M7_HUMAN,tr|A0A7I2YQH0|A0A7I2YQH0_HUMAN" 4 1231.6859 0.92 29205 13149 3 1231.683722 411.5693 Ras GTPase-activating protein-binding protein 1 OS=Homo sapiens OX=9606 GN=G3BP1 PE=1 SV=1 12 2577 - 607149 - - - -1.8065 - 1.708 0.133 - 164.2 1 2 0 -0.0022 10 0 0 0 3.06E+07 3.33E+07 - - - 1.5856 0.9993 221125_WJC_METTL3_EV_vs_WT_F03.13150.13150.2 0.018 24-Nov K.AANVLLSEQGDVK[136.11].L "sp|Q9P289|STK26_HUMAN,sp|O00506|STK25_HUMAN,tr|C9JDH9|C9JDH9_HUMAN,tr|C9J232|C9J232_HUMAN,tr|B4E0Y9|B4E0Y9_HUMAN,tr|C9JJV0|C9JJV0_HUMAN,tr|Q8NBY1|Q8NBY1_HUMAN,tr|H7C279|H7C279_HUMAN,tr|C9JCC0|C9JCC0_HUMAN,tr|C9J6L2|C9J6L2_HUMAN" 10 1350.7234 1.39 29206 13150 2 1350.720995 676.369 Serine\threonine-protein kinase 26 OS=Homo sapiens OX=9606 GN=STK26 PE=1 SV=2 4.37 2577.1 - 561859 - - - -1.8138 - 1.931 0.36 - 310.3 1 2 0 -0.0024 13 0 0 0 2.51E+07 1.80E+07 - - - 3.3881 0.998 221125_WJC_METTL3_EV_vs_WT_F03.13153.13153.2 0.00203 14-Aug K.YETELNLR.M sp|P02533|K1C14_HUMAN 1 1036.5189 65.2 29208 13153 2 1036.51902 519.2667 "Keratin, type I cytoskeletal 14 OS=Homo sapiens OX=9606 GN=KRT14 PE=1 SV=4" 4.53 2577.5 - 5.36E+07 - - - 0.0917 - 1.575 0.185 - 171.5 1 2 0 0.0001 8 0 0 0 1.14E+09 1.74E+07 - - - 1.7774 0.9992 221125_WJC_METTL3_EV_vs_WT_F03.13155.13155.2 3.09E-06 22-Oct R.AQPSVSLGAPYR.G sp|Q96PK6|RBM14_HUMAN 1 1244.6513 1.87 29209 13155 2 1244.648386 623.3329 RNA-binding protein 14 OS=Homo sapiens OX=9606 GN=RBM14 PE=1 SV=2 8.79 2577.7 - 3.73E+07 - - - -2.3701 - 2.202 0.337 - 377.6 1 2 0 -0.0029 12 0 0 0 2.23E+09 1.20E+09 - - - 3.6061 0.9966 221125_WJC_METTL3_EV_vs_WT_F03.13158.13158.2 0.00513 14-Aug R.NYYEQWGK[136.11].L "sp|P22626|ROA2_HUMAN,tr|A0A7I2YQN4|A0A7I2YQN4_HUMAN,tr|A0A7I2V4N0|A0A7I2V4N0_HUMAN,tr|A0A7I2V4N1|A0A7I2V4N1_HUMAN,tr|A0A7I2V4I6|A0A7I2V4I6_HUMAN,tr|A0A087WUI2|A0A087WUI2_HUMAN,tr|A0A7I2V4S4|A0A7I2V4S4_HUMAN,tr|A0A7I2V323|A0A7I2V323_HUMAN,tr|A0A7I2V3P1|A0A7I2V3P1_HUMAN,tr|A0A7I2V3P7|A0A7I2V3P7_HUMAN" 10 1094.4913 1.36 29212 13158 2 1094.487459 548.2529 Heterogeneous nuclear ribonucleoproteins A2\B1 OS=Homo sapiens OX=9606 GN=HNRNPA2B1 PE=1 SV=2 6 2577.8 - 4.10E+06 - - - -3.4728 - 1.414 0.387 - 245.2 1 2 0 -0.0038 8 0 0 0 1.31E+09 9.62E+08 - - - 2.943 0.9997 221125_WJC_METTL3_EV_vs_WT_F03.13159.13159.3 0.00421 13/44 K.VYIVHGVQEDLR[166.11].V sp|Q15024|EXOS7_HUMAN 1 1436.7651 0.82 29213 13159 3 1436.763139 479.929 Exosome complex component RRP42 OS=Homo sapiens OX=9606 GN=EXOSC7 PE=1 SV=3 5.32 2577.9 - 2.57E+06 - - - -1.3885 - 1.979 0.358 - 137.4 1 2 0 -0.002 12 0 0 0 3.21E+07 3.91E+07 - - - 4.4228 0.9993 221125_WJC_METTL3_EV_vs_WT_F03.13168.13168.2 0.000187 20-Oct R.GGAEGELQALR.A sp|Q15149|PLEC_HUMAN 1 1099.5622 0.03 29219 13168 2 1099.559998 550.7884 Plectin OS=Homo sapiens OX=9606 GN=PLEC PE=1 SV=3 4.53 2579.1 - 1.77E+06 - - - -1.9899 - 1.897 0.356 - 302.1 1 2 0 -0.0022 11 0 0 0 3.89E+07 1.24E+09 - - - 3.4018 0.9991 221125_WJC_METTL3_EV_vs_WT_F03.13171.13171.2 0.00282 14-Jul R.NYYEQWGK.L "sp|P22626|ROA2_HUMAN,tr|A0A7I2YQN4|A0A7I2YQN4_HUMAN,tr|A0A7I2V4N0|A0A7I2V4N0_HUMAN,tr|A0A7I2V4N1|A0A7I2V4N1_HUMAN,tr|A0A7I2V4I6|A0A7I2V4I6_HUMAN,tr|A0A087WUI2|A0A087WUI2_HUMAN,tr|A0A7I2V4S4|A0A7I2V4S4_HUMAN,tr|A0A7I2V323|A0A7I2V323_HUMAN,tr|A0A7I2V3P1|A0A7I2V3P1_HUMAN,tr|A0A7I2V3P7|A0A7I2V3P7_HUMAN" 10 1086.4771 1.36 29220 13171 2 1086.475493 544.2458 Heterogeneous nuclear ribonucleoproteins A2\B1 OS=Homo sapiens OX=9606 GN=HNRNPA2B1 PE=1 SV=2 6 2579.4 - 1.37E+07 - - - -1.4423 - 1.285 0.415 - 164.6 1 2 0 -0.0016 8 0 0 0 1.31E+09 9.62E+08 - - - 2.862 0.9574 221125_WJC_METTL3_EV_vs_WT_F03.13174.13174.2 0.00383 18-Nov Q.PSVSLGAPYR.G sp|Q96PK6|RBM14_HUMAN 1 1045.5556 1.44 29223 13174 2 1045.552435 523.7851 RNA-binding protein 14 OS=Homo sapiens OX=9606 GN=RBM14 PE=1 SV=2 9.18 2579.8 - 764021 - - - -3.0692 - 2.241 0.424 - 652 1 1 0 -0.0032 10 0 0 0 2.57E+07 1.78E+07 - - - 4.424 0.9995 221125_WJC_METTL3_EV_vs_WT_F03.13178.13178.3 0.0211 Oct-44 K.NAGVEGSLIVEK.L "sp|P10809|CH60_HUMAN,tr|A0A7I2V2X6|A0A7I2V2X6_HUMAN,tr|A0A7I2YQK6|A0A7I2YQK6_HUMAN,tr|A0A7I2V599|A0A7I2V599_HUMAN" 4 1214.6507 1.45 29225 13178 3 1214.647689 405.8908 "60 kDa heat shock protein, mitochondrial OS=Homo sapiens OX=9606 GN=HSPD1 PE=1 SV=2" 4.53 2580.2 - 6.18E+06 - - - -2.4517 - 2.063 0.362 - 126.1 1 2 0 -0.003 12 0 0 0 1.73E+08 1.19E+08 - - - 4.5824 0.9999 221125_WJC_METTL3_EV_vs_WT_F03.13183.13183.2 1.95E-06 13/20 K.LNGTDPEDVIR[166.11].N "sp|O14950|ML12B_HUMAN,sp|P19105|ML12A_HUMAN,sp|P24844|MYL9_HUMAN,tr|J3KTJ1|J3KTJ1_HUMAN,tr|J3QRS3|J3QRS3_HUMAN" 5 1237.6178 1.35 29228 13183 2 1237.618324 619.8162 Myosin regulatory light chain 12B OS=Homo sapiens OX=9606 GN=MYL12B PE=1 SV=2 4.03 2580.8 - 5.69E+06 - - - 0.4226 - 2.523 0.505 - 507.3 1 2 0 0.0005 11 0 0 0 8.23E+08 6.11E+08 - - - 5.2743 0.9996 221125_WJC_METTL3_EV_vs_WT_F03.13186.13186.2 0.00227 20-Sep R.ISISTSGGSFR.N "sp|P13647|K2C5_HUMAN,tr|F8VV57|F8VV57_HUMAN" 2 1110.5669 2959.24 29230 13186 2 1110.566411 556.2907 "Keratin, type II cytoskeletal 5 OS=Homo sapiens OX=9606 GN=KRT5 PE=1 SV=3" 9.75 2581.1 - 4.18E+06 - - - -0.4736 - 1.97 0.342 - 177.9 1 2 0 -0.0005 11 0 0 0 3.50E+09 1.18E+06 - - - 3.4011 0.9995 221125_WJC_METTL3_EV_vs_WT_F03.13187.13187.2 0.00625 18-Nov K.GTNLIIQETR.Q "sp|Q7L590|MCM10_HUMAN,tr|Q5T670|Q5T670_HUMAN" 2 1143.6248 2.92 29231 13187 2 1143.623208 572.8197 Protein MCM10 homolog OS=Homo sapiens OX=9606 GN=MCM10 PE=1 SV=2 6 2581.2 - 1.14E+06 - - - -1.3807 - 2.076 0.305 - 474.7 1 2 0 -0.0016 10 0 0 0 2.26E+07 7.74E+06 - - - 3.3321 0.9998 221125_WJC_METTL3_EV_vs_WT_F03.13190.13190.2 3.01E-07 22-Oct R.AQPSVSLGAPYR[166.11].G sp|Q96PK6|RBM14_HUMAN 1 1254.6596 2.46 29233 13190 2 1254.657072 628.3371 RNA-binding protein 14 OS=Homo sapiens OX=9606 GN=RBM14 PE=1 SV=2 8.79 2581.5 - 2.99E+07 - - - -2.0197 - 2.224 0.555 - 340 1 2 0 -0.0025 12 0 0 0 4.32E+09 1.76E+09 - - - 5.2425 0.9998 221125_WJC_METTL3_EV_vs_WT_F03.13193.13193.2 0.00337 18-Dec K.TLEELDPESR.E sp|Q6P161|RM54_HUMAN 1 1187.567 1.07 29235 13193 2 1187.564707 594.7908 "39S ribosomal protein L54, mitochondrial OS=Homo sapiens OX=9606 GN=MRPL54 PE=1 SV=1" 4 2581.9 - 3.85E+06 - - - -1.9283 - 2.198 0.546 - 491.9 1 2 0 -0.0023 10 0 0 0 1.08E+08 1.01E+08 - - - 5.2713 0.9994 221125_WJC_METTL3_EV_vs_WT_F03.13194.13194.2 3.35E-05 16-Nov K.TVESITDIR[166.11].A sp|P11279|LAMP1_HUMAN 1 1042.5534 1.87 29236 13194 2 1042.552449 522.284 Lysosome-associated membrane glycoprotein 1 OS=Homo sapiens OX=9606 GN=LAMP1 PE=1 SV=3 4.37 2582 - 2.09E+06 - - - -0.9208 - 1.98 0.273 - 368.8 1 2 0 -0.001 9 0 0 0 1.07E+08 5.72E+07 - - - 3.0333 0.9978 221125_WJC_METTL3_EV_vs_WT_F03.13199.13199.2 0.00772 16-Jul R.AQYEEIALK.S sp|Q14CN4|K2C72_HUMAN 1 1063.555 51.41 29239 13199 2 1063.556673 532.7848 "Keratin, type II cytoskeletal 72 OS=Homo sapiens OX=9606 GN=KRT72 PE=1 SV=2" 4.53 2582.6 - 3.38E+06 - - - 1.5956 - 1.514 0.266 - 234.4 1 2 0 0.0017 9 0 0 0 1.89E+08 3.68E+06 - - - 2.2051 0.9806 221125_WJC_METTL3_EV_vs_WT_F03.13200.13200.3 0.0968 15/40 R.LTPYEVDELR[166.11]R[166.11].K "sp|Q92841|DDX17_HUMAN,tr|A0A5H1ZRQ2|A0A5H1ZRQ2_HUMAN,tr|A0A1X7SBZ2|A0A1X7SBZ2_HUMAN" 3 1409.7418 1.15 29240 13200 3 1409.736173 470.9212 Probable ATP-dependent RNA helicase DDX17 OS=Homo sapiens OX=9606 GN=DDX17 PE=1 SV=2 4.68 2582.7 - 2.17E+06 - - - -3.9695 - 1.962 0.198 - 281.6 1 2 0 -0.0056 11 0 0 0 5.10E+08 4.44E+08 - - - 2.6606 0.8416 221125_WJC_METTL3_EV_vs_WT_F03.13204.13204.2 3.31 14-May R.QPQNGDLK.K tr|B0QYW2|B0QYW2_HUMAN 1 898.4508 1.16 29242 13204 2 898.45241 450.2327 PHD finger protein 21B (Fragment) OS=Homo sapiens OX=9606 GN=PHF21B PE=1 SV=8 5.84 2583.1 - 3.82E+06 - - - 1.7419 - 1.044 0.022 - 104.5 2 2 0 0.0016 8 0 0 0 9.21E+07 7.97E+07 - - - -0.8016 0.9914 221125_WJC_METTL3_EV_vs_WT_F03.13206.13206.2 0.0145 20-Sep K.LNGTDPEDVIR.N "sp|O14950|ML12B_HUMAN,sp|P19105|ML12A_HUMAN,sp|P24844|MYL9_HUMAN,tr|J3KTJ1|J3KTJ1_HUMAN,tr|J3QRS3|J3QRS3_HUMAN" 5 1227.6095 1.35 29244 13206 2 1227.605783 614.812 Myosin regulatory light chain 12B OS=Homo sapiens OX=9606 GN=MYL12B PE=1 SV=2 4.03 2583.3 - 6.09E+07 - - - -3.0531 - 1.396 0.258 - 223.3 1 2 0 -0.0037 11 0 0 0 8.44E+08 6.26E+08 - - - 1.8479 0.9998 221125_WJC_METTL3_EV_vs_WT_F03.13210.13210.2 2.98E-05 18-Dec K.AAMIVNQLSK.K "sp|P14923|PLAK_HUMAN,tr|C9JKY1|C9JKY1_HUMAN,tr|C9JK18|C9JK18_HUMAN,tr|C9JTX4|C9JTX4_HUMAN,tr|C9J826|C9J826_HUMAN" 5 1073.5903 0.79 29247 13210 2 1073.588491 537.8024 Junction plakoglobin OS=Homo sapiens OX=9606 GN=JUP PE=1 SV=3 8.8 2583.7 - 1.05E+07 - - - -1.699 - 2.182 0.515 - 494.3 1 2 0 -0.0018 10 0 0 0 3.12E+08 3.95E+08 - - - 5.0221 0.9983 221125_WJC_METTL3_EV_vs_WT_F03.13213.13213.3 0.00411 Dec-40 R.QGVDADINGLR.Q "sp|P35527|K1C9_HUMAN,tr|K7EQQ3|K7EQQ3_HUMAN" 2 1156.5837 41.79 29249 13213 3 1156.580465 386.5352 "Keratin, type I cytoskeletal 9 OS=Homo sapiens OX=9606 GN=KRT9 PE=1 SV=3" 4.21 2584 - 2.37E+06 - - - -2.7538 - 1.611 0.348 - 134.5 1 2 0 -0.0032 11 0 0 0 5.59E+07 1.34E+06 - - - 3.7736 0.9995 221125_WJC_METTL3_EV_vs_WT_F03.13214.13214.2 0.00648 16-Oct K.MNLSAIQDR.E "sp|Q96BM9|ARL8A_HUMAN,sp|Q9NVJ2|ARL8B_HUMAN" 2 1046.5179 1.53 29250 13214 2 1046.518681 524.2662 ADP-ribosylation factor-like protein 8A OS=Homo sapiens OX=9606 GN=ARL8A PE=1 SV=1 5.59 2584.1 - 2.40E+06 - - - 0.7664 - 1.711 0.355 - 443 1 2 0 0.0008 9 0 0 0 1.72E+08 1.13E+08 - - - 3.2166 0.9999 221125_WJC_METTL3_EV_vs_WT_F03.13219.13219.3 2.36E-05 15/40 R.LTPYEVDELRR.K "sp|Q92841|DDX17_HUMAN,tr|A0A5H1ZRQ2|A0A5H1ZRQ2_HUMAN,tr|A0A1X7SBZ2|A0A1X7SBZ2_HUMAN" 3 1389.7252 1.15 29252 13219 3 1389.723113 464.249 Probable ATP-dependent RNA helicase DDX17 OS=Homo sapiens OX=9606 GN=DDX17 PE=1 SV=2 4.68 2584.8 - 6.01E+06 - - - -1.5226 - 2.6 0.434 - 471.8 1 2 0 -0.0021 11 0 0 0 5.10E+08 4.44E+08 - - - 6.0925 0.9739 221125_WJC_METTL3_EV_vs_WT_F03.13221.13221.2 0.0247 16-Jun R.LHVSNIPFR.F "sp|O43251|RFOX2_HUMAN,sp|Q9NWB1|RFOX1_HUMAN,sp|A6NFN3|RFOX3_HUMAN,tr|A0A6Q8PGE0|A0A6Q8PGE0_HUMAN,tr|A0A6Q8PH77|A0A6Q8PH77_HUMAN,tr|A0A286YEU2|A0A286YEU2_HUMAN,tr|A0A087X2B1|A0A087X2B1_HUMAN,tr|F8VR27|F8VR27_HUMAN,tr|B7Z1U7|B7Z1U7_HUMAN,tr|B0QYY6|B0QYY6_HUMAN,tr|B0QYV1|B0QYV1_HUMAN,tr|A0A6Q8PHA3|A0A6Q8PHA3_HUMAN,tr|A0A3B3ITL7|A0A3B3ITL7_HUMAN,tr|F8VZY7|F8VZY7_HUMAN,tr|B0QYY4|B0QYY4_HUMAN,tr|J3KNW3|J3KNW3_HUMAN,tr|F8VZG9|F8VZG9_HUMAN,tr|J3QRF4|J3QRF4_HUMAN,tr|F8VRS4|F8VRS4_HUMAN,tr|A0A6Q8PFM4|A0A6Q8PFM4_HUMAN,tr|S4R469|S4R469_HUMAN,tr|A0A804HKG7|A0A804HKG7_HUMAN,tr|A0A0G2JRA5|A0A0G2JRA5_HUMAN,tr|A0A804HJM2|A0A804HJM2_HUMAN,tr|J3QQZ2|J3QQZ2_HUMAN,tr|I3L1D4|I3L1D4_HUMAN,tr|B0QYY7|B0QYY7_HUMAN,tr|A0A0G2JSB3|A0A0G2JSB3_HUMAN" 28 1081.6033 1.22 29254 13221 2 1081.600237 541.8089 RNA binding protein fox-1 homolog 2 OS=Homo sapiens OX=9606 GN=RBFOX2 PE=1 SV=3 9.76 2584.9 - 5.72E+06 - - - -2.7977 - 1.305 0.144 - 131.3 1 2 0 -0.003 9 0 0 0 5.12E+08 4.20E+08 - - - 0.8738 1 221125_WJC_METTL3_EV_vs_WT_F03.13222.13222.2 5.86E-06 14/24 R.ELAEDGYSGVEVR.V "sp|P23396|RS3_HUMAN,tr|H0YEU2|H0YEU2_HUMAN,tr|E9PL09|E9PL09_HUMAN,tr|E9PK82|E9PK82_HUMAN,tr|F2Z2S8|F2Z2S8_HUMAN,tr|H0YCJ7|H0YCJ7_HUMAN,tr|E9PQ96|E9PQ96_HUMAN,tr|E9PJH4|E9PJH4_HUMAN,tr|E9PPU1|E9PPU1_HUMAN,tr|H0YF32|H0YF32_HUMAN" 10 1422.6627 0.75 29255 13222 2 1422.661761 712.3386 40S ribosomal protein S3 OS=Homo sapiens OX=9606 GN=RPS3 PE=1 SV=2 4 2585.1 - 2.73E+06 - - - -0.6516 - 2.736 0.577 - 751.1 1 2 0 -0.0009 13 0 0 0 1.91E+09 2.54E+09 - - - 5.8856 0.9997 221125_WJC_METTL3_EV_vs_WT_F03.13224.13224.2 0.0096 22-Oct K.LDELQASDVSVK.Y sp|P12270|TPR_HUMAN 1 1302.6667 5.68 29256 13224 2 1302.664102 652.3406 Nucleoprotein TPR OS=Homo sapiens OX=9606 GN=TPR PE=1 SV=3 4.03 2585.3 - 1.35E+07 - - - -2.0028 - 2.451 0.457 - 301.8 1 2 0 -0.0026 12 0 0 0 4.16E+08 7.33E+07 - - - 4.7744 0.9979 221125_WJC_METTL3_EV_vs_WT_F03.13226.13226.2 0.00509 14-Sep K.VENLFNEK[136.11].C "sp|P78347|GTF2I_HUMAN,tr|A0A494C1K3|A0A494C1K3_HUMAN" 2 999.5117 1.32 29257 13226 2 999.510769 500.7631 General transcription factor II-I OS=Homo sapiens OX=9606 GN=GTF2I PE=1 SV=2 4.53 2585.5 - 3.18E+06 - - - -0.8924 - 1.698 0.166 - 265.7 1 2 0 -0.0009 8 0 0 0 6.64E+08 5.02E+08 - - - 1.8636 0.9997 221125_WJC_METTL3_EV_vs_WT_F03.13227.13227.2 7.06E-05 13/20 K.LANTC[160.03]FNEIEK.Q "sp|Q9NP61|ARFG3_HUMAN,tr|H0Y6A0|H0Y6A0_HUMAN" 2 1337.6286 1.04 29258 13227 2 1337.625243 669.8216 ADP-ribosylation factor GTPase-activating protein 3 OS=Homo sapiens OX=9606 GN=ARFGAP3 PE=1 SV=1 4.53 2585.5 - 3.12E+06 - - - -2.4738 - 2.613 0.455 - 558.1 1 2 0 -0.0033 11 0 0 0 2.69E+08 2.58E+08 - - - 4.999 0.9996 221125_WJC_METTL3_EV_vs_WT_F03.13228.13228.2 0.000315 20-Nov K.LANTC[160.03]FNEIEK[136.11].Q "sp|Q9NP61|ARFG3_HUMAN,tr|H0Y6A0|H0Y6A0_HUMAN" 2 1345.6428 1.08 29259 13228 2 1345.639556 673.8287 ADP-ribosylation factor GTPase-activating protein 3 OS=Homo sapiens OX=9606 GN=ARFGAP3 PE=1 SV=1 4.53 2585.6 - 3.97E+06 - - - -2.3751 - 2.528 0.436 - 488.2 1 2 0 -0.0032 11 0 0 0 2.67E+08 2.48E+08 - - - 4.7692 0.9963 221125_WJC_METTL3_EV_vs_WT_F03.13229.13229.2 0.0149 14-Sep K.VENLFNEK.C "sp|P78347|GTF2I_HUMAN,tr|A0A494C1K3|A0A494C1K3_HUMAN" 2 991.4975 1.39 29260 13229 2 991.495237 496.756 General transcription factor II-I OS=Homo sapiens OX=9606 GN=GTF2I PE=1 SV=2 4.53 2585.7 - 2.80E+06 - - - -2.2431 - 1.636 0.206 - 274.4 1 2 0 -0.0022 8 0 0 0 7.02E+08 5.04E+08 - - - 2.0464 0.9983 221125_WJC_METTL3_EV_vs_WT_F03.13231.13231.2 0.0115 20-Sep R.LTPYEVDELR[166.11]R[166.11].K "sp|Q92841|DDX17_HUMAN,tr|A0A5H1ZRQ2|A0A5H1ZRQ2_HUMAN,tr|A0A1X7SBZ2|A0A1X7SBZ2_HUMAN" 3 1409.7418 0.99 29262 13231 2 1409.738535 705.8782 Probable ATP-dependent RNA helicase DDX17 OS=Homo sapiens OX=9606 GN=DDX17 PE=1 SV=2 4.68 2585.9 - 1.40E+06 - - - -2.294 - 1.543 0.346 - 143 1 2 0 -0.0032 11 0 0 0 5.06E+07 5.09E+07 - - - 2.7689 0.9885 221125_WJC_METTL3_EV_vs_WT_F03.13234.13234.2 0.000107 16-Oct K.TYAIC[160.03]GAIR[166.11].R "sp|P63220|RS21_HUMAN,tr|Q9BYK1|Q9BYK1_HUMAN,tr|Q8WVC2|Q8WVC2_HUMAN" 3 1033.5254 0.52 29263 13234 2 1033.518042 517.77 40S ribosomal protein S21 OS=Homo sapiens OX=9606 GN=RPS21 PE=1 SV=1 7.89 2586.3 - 5.50E+06 - - - -7.1396 - 1.718 0.541 - 337.6 1 2 0 -0.0074 9 0 0 0 9.34E+07 1.81E+08 - - - 4.6001 0.9998 221125_WJC_METTL3_EV_vs_WT_F03.13235.13235.3 0.000201 Nov-36 K.VLSPYDLTHK.G sp|Q9NX20|RM16_HUMAN 1 1171.6237 0.78 29264 13235 3 1171.620942 391.5485 "39S ribosomal protein L16, mitochondrial OS=Homo sapiens OX=9606 GN=MRPL16 PE=1 SV=1" 6.71 2586.4 - 3.40E+06 - - - -2.3745 - 2.123 0.41 - 195.2 1 2 0 -0.0028 10 0 0 0 1.46E+08 1.88E+08 - - - 5.3089 0.9912 221125_WJC_METTL3_EV_vs_WT_F03.13236.13236.2 1.01 12-Aug K.FIEIAAR[166.11].K "sp|Q00839|HNRPU_HUMAN,tr|A0A1W2PQL0|A0A1W2PQL0_HUMAN,tr|A0A1W2PPE9|A0A1W2PPE9_HUMAN,tr|A0A1W2PPL4|A0A1W2PPL4_HUMAN,tr|A0A1W2PQ74|A0A1W2PQ74_HUMAN,tr|Q5RI18|Q5RI18_HUMAN,tr|A0A1W2PP35|A0A1W2PP35_HUMAN,tr|A0A1W2PPS1|A0A1W2PPS1_HUMAN,tr|A0A1W2PRZ7|A0A1W2PRZ7_HUMAN,tr|A0A1W2PPH7|A0A1W2PPH7_HUMAN,tr|A0A1W2PQD4|A0A1W2PQD4_HUMAN,tr|A0A1W2PP34|A0A1W2PP34_HUMAN,tr|A0A1X7SBS1|A0A1X7SBS1_HUMAN" 13 828.4733 0.88 29265 13236 2 828.471402 415.2439 Heterogeneous nuclear ribonucleoprotein U OS=Homo sapiens OX=9606 GN=HNRNPU PE=1 SV=6 6 2586.5 - 2.83E+06 - - - -2.3006 - 1.477 0.153 - 207.7 1 2 0 -0.0019 7 0 0 0 4.36E+07 4.96E+07 - - - 1.4062 0.981 221125_WJC_METTL3_EV_vs_WT_F03.13237.13237.2 1.77 12-Aug K.FIEIAAR.K "sp|Q00839|HNRPU_HUMAN,tr|A0A1W2PQL0|A0A1W2PQL0_HUMAN,tr|A0A1W2PPE9|A0A1W2PPE9_HUMAN,tr|A0A1W2PPL4|A0A1W2PPL4_HUMAN,tr|A0A1W2PQ74|A0A1W2PQ74_HUMAN,tr|Q5RI18|Q5RI18_HUMAN,tr|A0A1W2PP35|A0A1W2PP35_HUMAN,tr|A0A1W2PPS1|A0A1W2PPS1_HUMAN,tr|A0A1W2PRZ7|A0A1W2PRZ7_HUMAN,tr|A0A1W2PPH7|A0A1W2PPH7_HUMAN,tr|A0A1W2PQD4|A0A1W2PQD4_HUMAN,tr|A0A1W2PP34|A0A1W2PP34_HUMAN,tr|A0A1X7SBS1|A0A1X7SBS1_HUMAN" 13 818.465 0.86 29266 13237 2 818.46212 410.2398 Heterogeneous nuclear ribonucleoprotein U OS=Homo sapiens OX=9606 GN=HNRNPU PE=1 SV=6 6 2586.6 - 1.33E+06 - - - -3.5652 - 1.534 0.152 - 251.3 1 2 0 -0.0029 7 0 0 0 4.36E+07 5.08E+07 - - - 1.5185 0.9511 221125_WJC_METTL3_EV_vs_WT_F03.13239.13239.2 2.59 16-May R.TIGISVDPR[166.11].R "sp|P26373|RL13_HUMAN,tr|J3QSB4|J3QSB4_HUMAN" 2 966.5374 1.08 29267 13239 2 966.536367 484.276 60S ribosomal protein L13 OS=Homo sapiens OX=9606 GN=RPL13 PE=1 SV=4 5.5 2586.8 - 1.78E+07 - - - -1.0326 - 0.965 0.103 - 74.2 1 2 0 -0.001 9 0 0 0 5.95E+08 5.52E+08 - - - -0.3016 0.9991 221125_WJC_METTL3_EV_vs_WT_F03.13243.13243.2 5.37E-05 14/20 K.ATQALVLAPTR[166.11].E "sp|P60842|IF4A1_HUMAN,tr|J3KTB5|J3KTB5_HUMAN,tr|J3KT12|J3KT12_HUMAN,tr|J3QKZ9|J3QKZ9_HUMAN,tr|J3QS69|J3QS69_HUMAN,tr|J3QL43|J3QL43_HUMAN,tr|J3KS25|J3KS25_HUMAN,tr|J3QLN6|J3QLN6_HUMAN,tr|J3QR64|J3QR64_HUMAN" 9 1149.6745 1.52 29269 13243 2 1149.679013 575.8445 Eukaryotic initiation factor 4A-I OS=Homo sapiens OX=9606 GN=EIF4A1 PE=1 SV=1 9.79 2587.3 - 2.45E+06 - - - 3.9011 - 2.801 0.469 - 999 1 2 0 0.0045 11 0 0 0 6.25E+07 4.12E+07 - - - 5.29 0.9975 221125_WJC_METTL3_EV_vs_WT_F03.13245.13245.2 0.0135 20-Nov K.ATQALVLAPTR.E "sp|P60842|IF4A1_HUMAN,tr|J3KTB5|J3KTB5_HUMAN,tr|J3KT12|J3KT12_HUMAN,tr|J3QKZ9|J3QKZ9_HUMAN,tr|J3QS69|J3QS69_HUMAN,tr|J3QL43|J3QL43_HUMAN,tr|J3KS25|J3KS25_HUMAN,tr|J3QLN6|J3QLN6_HUMAN,tr|J3QR64|J3QR64_HUMAN" 9 1139.6663 1.55 29270 13245 2 1139.663925 570.8404 Eukaryotic initiation factor 4A-I OS=Homo sapiens OX=9606 GN=EIF4A1 PE=1 SV=1 9.79 2587.5 - 2.01E+06 - - - -2.0471 - 1.545 0.279 - 350.3 1 2 0 -0.0023 11 0 0 0 6.39E+07 4.12E+07 - - - 2.2778 0.9994 221125_WJC_METTL3_EV_vs_WT_F03.13247.13247.2 0.0137 13/22 K.QGIVTPIEAQTR.V sp|P98175|RBM10_HUMAN 1 1311.7147 2.7 29272 13247 2 1311.711529 656.8646 RNA-binding protein 10 OS=Homo sapiens OX=9606 GN=RBM10 PE=1 SV=3 6 2587.7 - 4.26E+06 - - - -2.39 - 2.465 0.341 - 562.9 1 2 0 -0.0031 12 0 0 0 3.02E+08 1.12E+08 - - - 3.9325 0.9994 221125_WJC_METTL3_EV_vs_WT_F03.13248.13248.2 0.00495 20-Oct R.LTPYEVDELRR.K "sp|Q92841|DDX17_HUMAN,tr|A0A5H1ZRQ2|A0A5H1ZRQ2_HUMAN,tr|A0A1X7SBZ2|A0A1X7SBZ2_HUMAN" 3 1389.7252 1 29273 13248 2 1389.72432 695.8699 Probable ATP-dependent RNA helicase DDX17 OS=Homo sapiens OX=9606 GN=DDX17 PE=1 SV=2 4.68 2587.8 - 1.56E+06 - - - -0.6541 - 1.725 0.316 - 198.1 1 2 0 -0.0009 11 0 0 0 5.08E+07 5.09E+07 - - - 2.8497 0.9999 221125_WJC_METTL3_EV_vs_WT_F03.13249.13249.2 0.000565 22-Nov K.NLVPGESVYGEK.R "sp|P22087|FBRL_HUMAN,tr|M0R299|M0R299_HUMAN,tr|M0R0P1|M0R0P1_HUMAN,tr|M0R1H0|M0R1H0_HUMAN,tr|M0QXL5|M0QXL5_HUMAN,tr|M0R2Q4|M0R2Q4_HUMAN,tr|M0R2B0|M0R2B0_HUMAN,tr|M0R2U2|M0R2U2_HUMAN" 8 1290.6456 0.9 29274 13249 2 1290.64588 646.3301 rRNA 2'-O-methyltransferase fibrillarin OS=Homo sapiens OX=9606 GN=FBL PE=1 SV=2 4.53 2587.9 - 1.26E+06 - - - 0.2309 - 2.065 0.501 - 337.3 1 2 0 0.0003 12 0 0 0 5.46E+08 6.08E+08 - - - 4.6492 0.8493 221125_WJC_METTL3_EV_vs_WT_F03.13250.13250.2 0.0117 20-Sep L.AEDGYSGVEVR.V "sp|P23396|RS3_HUMAN,tr|H0YEU2|H0YEU2_HUMAN,tr|E9PL09|E9PL09_HUMAN,tr|E9PK82|E9PK82_HUMAN,tr|F2Z2S8|F2Z2S8_HUMAN,tr|H0YCJ7|H0YCJ7_HUMAN,tr|E9PQ96|E9PQ96_HUMAN,tr|E9PJH4|E9PJH4_HUMAN,tr|E9PPU1|E9PPU1_HUMAN,tr|H0YF32|H0YF32_HUMAN" 10 1180.536 999 29275 13250 2 1180.535611 591.2753 40S ribosomal protein S3 OS=Homo sapiens OX=9606 GN=RPS3 PE=1 SV=2 4.14 2588.1 - 2.08E+06 - - - -0.3558 - 1.294 0.238 - 159 1 1 0 -0.0004 11 0 0 0 1.15E+07 0.00E+00 - - - 1.496 0.9893 221125_WJC_METTL3_EV_vs_WT_F03.13252.13252.3 0.149 Aug-36 K.VLSPYDLTHK[136.11].G sp|Q9NX20|RM16_HUMAN 1 1179.6379 0.78 29276 13252 3 1179.635427 394.2199 "39S ribosomal protein L16, mitochondrial OS=Homo sapiens OX=9606 GN=MRPL16 PE=1 SV=1" 6.71 2588.3 - 4.29E+06 - - - -2.1168 - 1.619 0.2 - 98.4 1 2 0 -0.0025 10 0 0 0 1.46E+08 1.87E+08 - - - 2.1762 1 221125_WJC_METTL3_EV_vs_WT_F03.13254.13254.3 5.21E-06 15/52 R.IFHTVTTTDDPVIR.K "sp|O15371|EIF3D_HUMAN,tr|B0QYA5|B0QYA5_HUMAN,tr|B0QYA4|B0QYA4_HUMAN" 3 1613.8413 1.24 29277 13254 3 1613.837681 538.9544 Eukaryotic translation initiation factor 3 subunit D OS=Homo sapiens OX=9606 GN=EIF3D PE=1 SV=1 5.21 2588.5 - 7.15E+06 - - - -2.2561 - 2.854 0.516 - 275.4 1 2 0 -0.0036 14 0 0 0 3.67E+08 2.95E+08 - - - 7.0789 0.9993 221125_WJC_METTL3_EV_vs_WT_F03.13255.13255.2 0.00201 16-Sep R.GPFADENFK.L "sp|O43447|PPIH_HUMAN,tr|H0YEL5|H0YEL5_HUMAN,tr|A0A7I2YQS4|A0A7I2YQS4_HUMAN,tr|C9JQD4|C9JQD4_HUMAN" 4 1023.4662 3.33 29278 13255 2 1023.464214 512.7404 Peptidyl-prolyl cis-trans isomerase H OS=Homo sapiens OX=9606 GN=PPIH PE=1 SV=1 4.37 2588.5 - 8.01E+06 - - - -1.9024 - 1.508 0.437 - 261.4 1 2 0 -0.0019 9 0 0 0 9.62E+08 2.88E+08 - - - 3.4565 0.9683 221125_WJC_METTL3_EV_vs_WT_F03.13256.13256.2 0.00355 18-Sep N.GILNVTATDK[136.11].S "sp|P0DMV8|HS71A_HUMAN,sp|P34931|HS71L_HUMAN,sp|P0DMV9|HS71B_HUMAN,tr|V9GZ37|V9GZ37_HUMAN,tr|A0A0G2JIW1|A0A0G2JIW1_HUMAN" 5 1038.5801 0.13 29279 13256 2 1038.578089 520.2973 Heat shock 70 kDa protein 1A OS=Homo sapiens OX=9606 GN=HSPA1A PE=1 SV=1 5.84 2588.6 - 2.56E+07 - - - -1.9122 - 1.908 0.388 - 276.6 1 1 0 -0.002 10 0 0 0 9.76E+07 7.59E+08 - - - 3.7095 1 221125_WJC_METTL3_EV_vs_WT_F03.13258.13258.2 9.77E-09 16/24 R.ILDETQEAVEYQR.Q "sp|Q96FZ7|CHMP6_HUMAN,tr|I3L4A1|I3L4A1_HUMAN,tr|I3L3E4|I3L3E4_HUMAN,tr|I3L4G8|I3L4G8_HUMAN" 4 1592.7682 1.55 29281 13258 2 1592.766537 797.3914 Charged multivesicular body protein 6 OS=Homo sapiens OX=9606 GN=CHMP6 PE=1 SV=3 4 2588.7 - 3.70E+06 - - - -1.0541 - 2.803 0.614 - 518.2 1 2 0 -0.0017 13 0 0 0 2.31E+08 1.49E+08 - - - 6.2208 0.9998 221125_WJC_METTL3_EV_vs_WT_F03.13260.13260.2 1.72E-05 16-Sep R.LHVSNIPFR[166.11].F "sp|O43251|RFOX2_HUMAN,sp|Q9NWB1|RFOX1_HUMAN,sp|A6NFN3|RFOX3_HUMAN,tr|A0A6Q8PGE0|A0A6Q8PGE0_HUMAN,tr|A0A6Q8PH77|A0A6Q8PH77_HUMAN,tr|A0A286YEU2|A0A286YEU2_HUMAN,tr|A0A087X2B1|A0A087X2B1_HUMAN,tr|F8VR27|F8VR27_HUMAN,tr|B7Z1U7|B7Z1U7_HUMAN,tr|B0QYY6|B0QYY6_HUMAN,tr|B0QYV1|B0QYV1_HUMAN,tr|A0A6Q8PHA3|A0A6Q8PHA3_HUMAN,tr|A0A3B3ITL7|A0A3B3ITL7_HUMAN,tr|F8VZY7|F8VZY7_HUMAN,tr|B0QYY4|B0QYY4_HUMAN,tr|J3KNW3|J3KNW3_HUMAN,tr|F8VZG9|F8VZG9_HUMAN,tr|J3QRF4|J3QRF4_HUMAN,tr|F8VRS4|F8VRS4_HUMAN,tr|A0A6Q8PFM4|A0A6Q8PFM4_HUMAN,tr|S4R469|S4R469_HUMAN,tr|A0A804HKG7|A0A804HKG7_HUMAN,tr|A0A0G2JRA5|A0A0G2JRA5_HUMAN,tr|A0A804HJM2|A0A804HJM2_HUMAN,tr|J3QQZ2|J3QQZ2_HUMAN,tr|I3L1D4|I3L1D4_HUMAN,tr|B0QYY7|B0QYY7_HUMAN,tr|A0A0G2JSB3|A0A0G2JSB3_HUMAN" 28 1091.6115 1.24 29282 13260 2 1091.610021 546.813 RNA binding protein fox-1 homolog 2 OS=Homo sapiens OX=9606 GN=RBFOX2 PE=1 SV=3 9.76 2588.9 - 8.82E+06 - - - -1.3851 - 2.047 0.519 - 335 1 2 0 -0.0015 9 0 0 0 5.27E+08 4.26E+08 - - - 4.9464 0.9997 221125_WJC_METTL3_EV_vs_WT_F03.13262.13262.2 4.08E-09 14/24 R.ILDETQEAVEYQR[166.11].Q "sp|Q96FZ7|CHMP6_HUMAN,tr|I3L4A1|I3L4A1_HUMAN,tr|I3L3E4|I3L3E4_HUMAN,tr|I3L4G8|I3L4G8_HUMAN" 4 1602.7765 1.55 29283 13262 2 1602.772921 802.3955 Charged multivesicular body protein 6 OS=Homo sapiens OX=9606 GN=CHMP6 PE=1 SV=3 4 2589.1 - 3.19E+06 - - - -2.2243 - 2.914 0.463 - 808 1 2 0 -0.0036 13 0 0 0 2.31E+08 1.49E+08 - - - 5.2046 0.9998 221125_WJC_METTL3_EV_vs_WT_F03.13263.13263.3 5.81E-05 14/44 K.ISEAPFLHPAPR.S "sp|Q5VWN6|TASO2_HUMAN,tr|A0A2R8YH03|A0A2R8YH03_HUMAN" 2 1333.7143 2.51 29284 13263 3 1333.710947 445.5787 Protein TASOR 2 OS=Homo sapiens OX=9606 GN=TASOR2 PE=1 SV=1 6.75 2589.3 - 1.86E+06 - - - -2.4915 - 2.52 0.397 - 283.1 1 2 0 -0.0033 12 0 0 0 5.69E+07 2.27E+07 - - - 5.5271 0.9997 221125_WJC_METTL3_EV_vs_WT_F03.13264.13264.2 0.000729 15/22 K.QGIVTPIEAQTR[166.11].V sp|P98175|RBM10_HUMAN 1 1321.7229 2.7 29285 13264 2 1321.722913 661.8687 RNA-binding protein 10 OS=Homo sapiens OX=9606 GN=RBM10 PE=1 SV=3 6 2589.4 - 2.79E+06 - - - -0.0159 - 2.597 0.257 - 812 1 2 0 0 12 0 0 0 3.02E+08 1.12E+08 - - - 3.4503 0.8747 221125_WJC_METTL3_EV_vs_WT_F03.13265.13265.3 0.0908 Nov-40 K.ILHSYVPEEIR[166.11].D sp|Q96CB9|NSUN4_HUMAN 1 1364.7328 0.87 29286 13265 3 1364.727882 455.9182 5-methylcytosine rRNA methyltransferase NSUN4 OS=Homo sapiens OX=9606 GN=NSUN4 PE=1 SV=2 5.4 2589.5 - 1.29E+06 - - - -3.5824 - 1.612 0.124 - 176.3 1 2 0 -0.0049 11 0 0 0 1.02E+07 1.17E+07 - - - 1.2776 0.9995 221125_WJC_METTL3_EV_vs_WT_F03.13269.13269.3 0.000771 Dec-52 R.IFHTVTTTDDPVIR[166.11].K "sp|O15371|EIF3D_HUMAN,tr|B0QYA5|B0QYA5_HUMAN,tr|B0QYA4|B0QYA4_HUMAN" 3 1623.8496 1.24 29288 13269 3 1623.846311 542.2905 Eukaryotic translation initiation factor 3 subunit D OS=Homo sapiens OX=9606 GN=EIF3D PE=1 SV=1 5.21 2590 - 1.40E+07 - - - -2.0205 - 1.915 0.368 - 178 1 2 0 -0.0033 14 0 0 0 3.67E+08 2.95E+08 - - - 4.3686 0.9999 221125_WJC_METTL3_EV_vs_WT_F03.13270.13270.2 2.14E-06 22-Nov K.NLVPGESVYGEK[136.11].R "sp|P22087|FBRL_HUMAN,tr|M0R299|M0R299_HUMAN,tr|M0R0P1|M0R0P1_HUMAN,tr|M0R1H0|M0R1H0_HUMAN,tr|M0QXL5|M0QXL5_HUMAN,tr|M0R2Q4|M0R2Q4_HUMAN,tr|M0R2B0|M0R2B0_HUMAN,tr|M0R2U2|M0R2U2_HUMAN" 8 1298.6598 0.9 29289 13270 2 1298.658198 650.3372 rRNA 2'-O-methyltransferase fibrillarin OS=Homo sapiens OX=9606 GN=FBL PE=1 SV=2 4.53 2590.1 - 9.82E+06 - - - -1.2197 - 2.321 0.555 - 365.4 1 2 0 -0.0016 12 0 0 0 5.46E+08 6.08E+08 - - - 5.3552 0.9998 221125_WJC_METTL3_EV_vs_WT_F03.13272.13272.2 2.47E-05 18-Oct R.GVDLSGNDFK.G "sp|Q13045|FLII_HUMAN,tr|J3KS54|J3KS54_HUMAN,tr|J3KS39|J3KS39_HUMAN" 3 1050.4982 0.71 29291 13272 2 1050.496505 526.2564 Protein flightless-1 homolog OS=Homo sapiens OX=9606 GN=FLII PE=1 SV=2 4.21 2590.3 - 1.81E+06 - - - -1.603 - 2.175 0.536 - 291.2 1 2 0 -0.0017 10 0 0 0 5.54E+07 7.80E+07 - - - 5.1683 0.9991 221125_WJC_METTL3_EV_vs_WT_F03.13273.13273.3 0.00482 14/44 K.ISEAPFLHPAPR[166.11].S "sp|Q5VWN6|TASO2_HUMAN,tr|A0A2R8YH03|A0A2R8YH03_HUMAN" 2 1343.7225 2.59 29292 13273 3 1343.716617 448.9148 Protein TASOR 2 OS=Homo sapiens OX=9606 GN=TASOR2 PE=1 SV=1 6.75 2590.4 - 1.79E+06 - - - -4.4079 - 2.752 0.359 - 309.6 1 2 0 -0.0059 12 0 0 0 5.74E+07 2.21E+07 - - - 5.3469 0.9516 221125_WJC_METTL3_EV_vs_WT_F03.13274.13274.2 0.0775 16-Sep K.TYELLNC[160.03]DK[136.11].H "sp|Q92979|NEP1_HUMAN,tr|A0A087WVM7|A0A087WVM7_HUMAN,tr|V9GYP5|V9GYP5_HUMAN,tr|A0A087WWQ2|A0A087WWQ2_HUMAN" 4 1162.542 0.63 29293 13274 2 1162.546745 582.2783 Ribosomal RNA small subunit methyltransferase NEP1 OS=Homo sapiens OX=9606 GN=EMG1 PE=1 SV=4 4.37 2590.6 - 2.21E+06 - - - 4.1031 - 1.265 0.189 - 185.6 1 2 0 0.0048 9 0 0 0 2.37E+07 3.77E+07 - - - 1.1155 0.9995 221125_WJC_METTL3_EV_vs_WT_F03.13276.13276.2 8.46E-05 18-Oct K.STVVPVPYEK[136.11].M "sp|P78347|GTF2I_HUMAN,tr|A0A494C1K3|A0A494C1K3_HUMAN" 2 1125.6161 1.62 29294 13276 2 1125.613607 563.8153 General transcription factor II-I OS=Homo sapiens OX=9606 GN=GTF2I PE=1 SV=2 5.72 2590.8 - 1.59E+07 - - - -2.2379 - 1.86 0.447 - 365 1 2 0 -0.0025 10 0 0 0 4.30E+09 2.66E+09 - - - 4.074 0.9848 221125_WJC_METTL3_EV_vs_WT_F03.13277.13277.2 0.000826 18-Oct N.GILNVTATDK[136.11].S "sp|P0DMV8|HS71A_HUMAN,sp|P34931|HS71L_HUMAN,sp|P0DMV9|HS71B_HUMAN,tr|V9GZ37|V9GZ37_HUMAN,tr|A0A0G2JIW1|A0A0G2JIW1_HUMAN" 5 1038.5801 0.13 29295 13277 2 1038.578383 520.2973 Heat shock 70 kDa protein 1A OS=Homo sapiens OX=9606 GN=HSPA1A PE=1 SV=1 5.84 2590.8 - 1.30E+07 - - - -1.6291 - 2.147 0.446 - 324.8 1 1 0 -0.0017 10 0 0 0 9.76E+07 7.59E+08 - - - 4.4674 0.9995 221125_WJC_METTL3_EV_vs_WT_F03.13278.13278.2 0.0152 14/20 K.IGGIGTVPVGR[166.11].V "sp|Q05639|EF1A2_HUMAN,sp|P68104|EF1A1_HUMAN,sp|Q5VTE0|EF1A3_HUMAN,tr|A0A7I2V659|A0A7I2V659_HUMAN,tr|A0A7I2V3H3|A0A7I2V3H3_HUMAN,tr|A0A2U3TZH3|A0A2U3TZH3_HUMAN,tr|A0A7I2V5N4|A0A7I2V5N4_HUMAN,tr|A0A087WVQ9|A0A087WVQ9_HUMAN" 8 1034.6112 0.34 29296 13278 2 1034.609347 518.3129 Elongation factor 1-alpha 2 OS=Homo sapiens OX=9606 GN=EEF1A2 PE=1 SV=1 9.75 2590.8 - 8.52E+06 - - - -1.79 - 2.04 0.371 - 717.6 1 2 0 -0.0019 11 0 0 0 2.38E+08 6.96E+08 - - - 3.7093 0.9991 221125_WJC_METTL3_EV_vs_WT_F03.13279.13279.3 0.00104 Dec-40 K.TAITVEHLAIK.C sp|Q9NR30|DDX21_HUMAN 1 1194.6972 0.93 29297 13279 3 1194.693333 399.2397 Nucleolar RNA helicase 2 OS=Homo sapiens OX=9606 GN=DDX21 PE=1 SV=5 6.41 2590.9 - 2.55E+06 - - - -3.2561 - 2.083 0.356 - 142.9 1 2 0 -0.0039 11 0 0 0 6.56E+07 7.04E+07 - - - 4.5926 0.9994 221125_WJC_METTL3_EV_vs_WT_F03.13280.13280.2 0.0061 20-Oct R.EGLGSNYLGGR[166.11].S sp|Q96CU9|FXRD1_HUMAN 1 1131.5548 2.19 29298 13280 2 1131.557003 566.7847 FAD-dependent oxidoreductase domain-containing protein 1 OS=Homo sapiens OX=9606 GN=FOXRED1 PE=1 SV=2 6.1 2591 - 2.31E+06 - - - 1.9416 - 2.202 0.338 - 220.8 1 2 0 0.0022 11 0 0 0 1.88E+08 8.61E+07 - - - 3.6722 0.9999 221125_WJC_METTL3_EV_vs_WT_F03.13286.13286.3 0.000106 17/48 R.ILDETQEAVEYQR.Q "sp|Q96FZ7|CHMP6_HUMAN,tr|I3L4A1|I3L4A1_HUMAN,tr|I3L3E4|I3L3E4_HUMAN,tr|I3L4G8|I3L4G8_HUMAN" 4 1592.7682 1.37 29302 13286 3 1592.765062 531.93 Charged multivesicular body protein 6 OS=Homo sapiens OX=9606 GN=CHMP6 PE=1 SV=3 4 2591.7 - 5.94E+06 - - - -1.9802 - 2.615 0.437 - 195.7 1 2 0 -0.0032 13 0 0 0 1.05E+08 7.66E+07 - - - 6.0175 0.9996 221125_WJC_METTL3_EV_vs_WT_F03.13288.13288.3 6.02E-05 13/48 R.ILDETQEAVEYQR[166.11].Q "sp|Q96FZ7|CHMP6_HUMAN,tr|I3L4A1|I3L4A1_HUMAN,tr|I3L3E4|I3L3E4_HUMAN,tr|I3L4G8|I3L4G8_HUMAN" 4 1602.7765 1.44 29304 13288 3 1602.770779 535.2661 Charged multivesicular body protein 6 OS=Homo sapiens OX=9606 GN=CHMP6 PE=1 SV=3 4 2591.9 - 2.75E+06 - - - -3.5607 - 2.469 0.4 - 210.5 1 2 0 -0.0057 13 0 0 0 1.04E+08 7.25E+07 - - - 5.4485 0.9997 221125_WJC_METTL3_EV_vs_WT_F03.13291.13291.2 7.73E-05 14-Jul K.EAIDSYIK[136.11].A "sp|Q00610|CLH1_HUMAN,tr|A0A087WVQ6|A0A087WVQ6_HUMAN" 2 945.4899 0.76 29306 13291 2 945.490235 473.7522 Clathrin heavy chain 1 OS=Homo sapiens OX=9606 GN=CLTC PE=1 SV=5 4.37 2592.2 - 6.02E+06 - - - 0.3934 - 1.596 0.447 - 137 1 2 0 0.0004 8 0 0 0 1.58E+08 2.08E+08 - - - 3.7524 0.9999 221125_WJC_METTL3_EV_vs_WT_F03.13295.13295.2 3.50E-06 15/26 R.IFHTVTTTDDPVIR.K "sp|O15371|EIF3D_HUMAN,tr|B0QYA5|B0QYA5_HUMAN,tr|B0QYA4|B0QYA4_HUMAN" 3 1613.8413 1.03 29308 13295 2 1613.840856 807.9279 Eukaryotic translation initiation factor 3 subunit D OS=Homo sapiens OX=9606 GN=EIF3D PE=1 SV=1 5.21 2592.7 - 1.45E+06 - - - -0.2888 - 2.485 0.514 - 497.3 1 2 0 -0.0005 14 0 0 0 2.11E+07 2.05E+07 - - - 5.1215 0.7716 221125_WJC_METTL3_EV_vs_WT_F03.13297.13297.2 0.131 14-Jul K.IELFGR[166.11]PH.N sp|Q86U44|MTA70_HUMAN 1 977.5322 0.02 29309 13297 2 977.529242 489.7734 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 6.75 2592.9 - 1.68E+08 - - - -3.0464 - 1.545 0.266 - 171.9 1 1 0 -0.003 8 0 0 0 7.20E+07 4.26E+09 - - - 2.3168 0.9996 221125_WJC_METTL3_EV_vs_WT_F03.13299.13299.2 0.0578 16-Jul R.GPFADENFK[136.11].L "sp|O43447|PPIH_HUMAN,tr|H0YEL5|H0YEL5_HUMAN,tr|A0A7I2YQS4|A0A7I2YQS4_HUMAN,tr|C9JQD4|C9JQD4_HUMAN" 4 1031.4804 3.34 29311 13299 2 1031.479529 516.7475 Peptidyl-prolyl cis-trans isomerase H OS=Homo sapiens OX=9606 GN=PPIH PE=1 SV=1 4.37 2593 - 1.00E+07 - - - -0.8066 - 1.741 0.378 - 177.2 1 2 0 -0.0008 9 0 0 0 9.61E+08 2.88E+08 - - - 3.4367 0.9968 221125_WJC_METTL3_EV_vs_WT_F03.13300.13300.3 0.211 Nov-40 K.TAITVEHLAIK[136.11].C sp|Q9NR30|DDX21_HUMAN 1 1202.7114 0.94 29312 13300 3 1202.707947 401.9111 Nucleolar RNA helicase 2 OS=Homo sapiens OX=9606 GN=DDX21 PE=1 SV=5 6.41 2593 - 3.59E+06 - - - -2.8901 - 1.651 0.305 - 88.2 1 2 0 -0.0035 11 0 0 0 6.62E+07 7.06E+07 - - - 3.3638 0.9997 221125_WJC_METTL3_EV_vs_WT_F03.13305.13305.2 0.000223 14-Sep R.QYFEEIQR[166.11].R "sp|Q9HCD5|NCOA5_HUMAN,tr|Q5JY17|Q5JY17_HUMAN" 2 1121.5381 1.23 29315 13305 2 1121.536469 561.7763 Nuclear receptor coactivator 5 OS=Homo sapiens OX=9606 GN=NCOA5 PE=1 SV=2 4.53 2593.6 - 6.92E+06 - - - -1.4489 - 1.741 0.482 - 361.8 1 2 0 -0.0016 8 0 0 0 3.21E+08 2.62E+08 - - - 4.2728 0.9993 221125_WJC_METTL3_EV_vs_WT_F03.13307.13307.2 0.000475 22-Nov R.FTAIIGPNGSGK[136.11].S sp|Q14683|SMC1A_HUMAN 1 1168.6332 0.77 29317 13307 2 1168.631136 585.3239 Structural maintenance of chromosomes protein 1A OS=Homo sapiens OX=9606 GN=SMC1A PE=1 SV=2 8.75 2593.9 - 1.59E+06 - - - -1.7431 - 1.731 0.379 - 267.3 1 2 0 -0.002 12 0 0 0 7.79E+07 1.02E+08 - - - 3.2834 0.9997 221125_WJC_METTL3_EV_vs_WT_F03.13309.13309.2 2.06E-05 13/22 K.VAVGELTDEDVK[136.11].M "sp|P49736|MCM2_HUMAN,tr|H0Y8E6|H0Y8E6_HUMAN" 2 1281.6544 1.53 29319 13309 2 1281.657225 641.8345 DNA replication licensing factor MCM2 OS=Homo sapiens OX=9606 GN=MCM2 PE=1 SV=4 3.92 2594.1 - 1.46E+06 - - - 2.2338 - 2.668 0.498 - 544.6 1 2 0 0.0029 12 0 0 0 6.69E+07 4.38E+07 - - - 5.3004 0.9988 221125_WJC_METTL3_EV_vs_WT_F03.13312.13312.2 0.00168 18-Oct K.QSLPPGLAVK.E sp|P63173|RL38_HUMAN 1 1008.5968 1.19 29321 13312 2 1008.595027 505.3057 60S ribosomal protein L38 OS=Homo sapiens OX=9606 GN=RPL38 PE=1 SV=2 8.75 2594.4 - 9.07E+07 - - - -1.739 - 1.634 0.314 - 394.6 1 2 0 -0.0018 10 0 0 0 4.19E+09 3.53E+09 - - - 2.7303 0.9998 221125_WJC_METTL3_EV_vs_WT_F03.13317.13317.2 4.55E-05 24-Nov R.YLEC[160.03]SALQQDGVK[136.11].E sp|P84095|RHOG_HUMAN 1 1517.7275 0.61 29325 13317 2 1517.724985 759.871 Rho-related GTP-binding protein RhoG OS=Homo sapiens OX=9606 GN=RHOG PE=1 SV=1 4.37 2595 - 912948 - - - -1.6861 - 2.244 0.564 - 286.6 1 2 0 -0.0026 13 0 0 0 1.02E+07 1.68E+07 - - - 5.2803 0.9995 221125_WJC_METTL3_EV_vs_WT_F03.13318.13318.2 1.66E-05 24-Dec R.YLEC[160.03]SALQQDGVK.E sp|P84095|RHOG_HUMAN 1 1509.7133 0.61 29326 13318 2 1509.70834 755.8639 Rho-related GTP-binding protein RhoG OS=Homo sapiens OX=9606 GN=RHOG PE=1 SV=1 4.37 2595.1 - 520189 - - - -3.3145 - 2.382 0.589 - 423.5 1 2 0 -0.005 13 0 0 0 1.02E+07 1.68E+07 - - - 5.6174 0.9971 221125_WJC_METTL3_EV_vs_WT_F03.13324.13324.2 0.183 22-Sep R.VATGTDLLSGTR.D sp|O75342|LX12B_HUMAN 1 1189.6303 156.72 29330 13324 2 1189.626147 595.8224 "Arachidonate 12-lipoxygenase, 12R-type OS=Homo sapiens OX=9606 GN=ALOX12B PE=1 SV=1" 5.81 2595.7 - 2.33E+06 - - - -3.4624 - 1.904 0.319 - 194.1 1 2 0 -0.0041 12 0 0 0 5.89E+07 3.76E+05 - - - 3.0902 0.9988 221125_WJC_METTL3_EV_vs_WT_F03.13326.13326.2 0.00963 18-Sep R.VLNNFISNQK.M sp|P46013|KI67_HUMAN 1 1175.6299 1.06 29332 13326 2 1175.626968 588.8222 Proliferation marker protein Ki-67 OS=Homo sapiens OX=9606 GN=MKI67 PE=1 SV=2 8.72 2595.9 - 848603 - - - -2.4702 - 1.896 0.327 - 249.3 1 2 0 -0.0029 10 0 0 0 1.61E+07 1.52E+07 - - - 3.241 0.9998 221125_WJC_METTL3_EV_vs_WT_F03.13329.13329.2 8.20E-05 13/22 R.IVALSSSLSNAK.D sp|O75643|U520_HUMAN 1 1188.6714 0.4 29333 13329 2 1188.670413 595.343 U5 small nuclear ribonucleoprotein 200 kDa helicase OS=Homo sapiens OX=9606 GN=SNRNP200 PE=1 SV=2 8.75 2596.3 - 3.47E+06 - - - -0.8329 - 2.172 0.478 - 543 1 2 0 -0.001 12 0 0 0 1.38E+08 3.42E+08 - - - 4.6121 1 221125_WJC_METTL3_EV_vs_WT_F03.13333.13333.2 1.73E-06 24-Nov R.ELAEDGYSGVEVR[166.11].V "sp|P23396|RS3_HUMAN,tr|H0YEU2|H0YEU2_HUMAN,tr|E9PL09|E9PL09_HUMAN,tr|E9PK82|E9PK82_HUMAN,tr|F2Z2S8|F2Z2S8_HUMAN,tr|H0YCJ7|H0YCJ7_HUMAN,tr|E9PQ96|E9PQ96_HUMAN,tr|E9PJH4|E9PJH4_HUMAN,tr|E9PPU1|E9PPU1_HUMAN,tr|H0YF32|H0YF32_HUMAN" 10 1432.671 0.75 29336 13333 2 1432.669661 717.3428 40S ribosomal protein S3 OS=Homo sapiens OX=9606 GN=RPS3 PE=1 SV=2 4 2596.7 - 1.93E+07 - - - -0.9053 - 2.535 0.613 - 438.7 1 2 0 -0.0013 13 0 0 0 1.92E+09 2.56E+09 - - - 5.9556 0.9962 221125_WJC_METTL3_EV_vs_WT_F03.13335.13335.2 0.392 14-Jul K.IEISELNR.V "sp|P04264|K2C1_HUMAN,sp|P35908|K22E_HUMAN" 2 972.524 296.33 29337 13335 2 972.523425 487.2693 "Keratin, type II cytoskeletal 1 OS=Homo sapiens OX=9606 GN=KRT1 PE=1 SV=6" 4.53 2596.9 - 1.92E+08 - - - -0.6015 - 1.627 0.113 - 164.4 1 2 0 -0.0006 8 0 0 0 5.74E+10 1.94E+08 - - - 1.3434 0.9981 221125_WJC_METTL3_EV_vs_WT_F03.13336.13336.2 0.422 18-Aug K.QSLPPGLAVK[136.11].E sp|P63173|RL38_HUMAN 1 1016.611 1.19 29338 13336 2 1016.609925 509.3128 60S ribosomal protein L38 OS=Homo sapiens OX=9606 GN=RPL38 PE=1 SV=2 8.75 2596.9 - 7.14E+07 - - - -1.0387 - 1.575 0.229 - 251.4 1 2 0 -0.0011 10 0 0 0 4.26E+09 3.59E+09 - - - 2 0.9972 221125_WJC_METTL3_EV_vs_WT_F03.13337.13337.2 0.0484 14-Jul K.DSIFEPAK[136.11].G "sp|P55265|DSRAD_HUMAN,tr|A0A3B3IRQ9|A0A3B3IRQ9_HUMAN,tr|A0A3B3ISU1|A0A3B3ISU1_HUMAN,tr|A0A7P0Z4K3|A0A7P0Z4K3_HUMAN,tr|A0A7P0Z4F9|A0A7P0Z4F9_HUMAN" 5 913.4636 0.77 29339 13337 2 913.462633 457.7391 Double-stranded RNA-specific adenosine deaminase OS=Homo sapiens OX=9606 GN=ADAR PE=1 SV=4 4.37 2597 - 1.55E+06 - - - -1.1112 - 1.195 0.289 - 145.5 1 2 0 -0.001 8 0 0 0 4.41E+07 5.71E+07 - - - 1.7125 0.9998 221125_WJC_METTL3_EV_vs_WT_F03.13344.13344.2 7.83E-05 18-Dec K.MADEAILQER.E sp|Q9HCD5|NCOA5_HUMAN 1 1174.5652 1.14 29344 13344 2 1174.566633 588.2899 Nuclear receptor coactivator 5 OS=Homo sapiens OX=9606 GN=NCOA5 PE=1 SV=2 4.14 2597.6 - 1.31E+06 - - - 1.2004 - 2.616 0.412 - 729.5 1 2 0 0.0014 10 0 0 0 1.83E+08 1.60E+08 - - - 4.7678 0.9859 221125_WJC_METTL3_EV_vs_WT_F03.13348.13348.2 1.09 12-Sep K.HIDFSLR.S sp|P46781|RS9_HUMAN 1 886.4661 0.61 29346 13348 2 886.464129 444.2403 40S ribosomal protein S9 OS=Homo sapiens OX=9606 GN=RPS9 PE=1 SV=3 6.74 2598.1 - 1.65E+06 - - - -2.2246 - 1.468 0.103 - 298.3 1 2 0 -0.002 7 0 0 0 5.80E+07 9.57E+07 - - - 1.0176 0.9993 221125_WJC_METTL3_EV_vs_WT_F03.13351.13351.2 0.000268 18-Nov R.SPDEPLPVVR.L sp|Q9NUL7|DDX28_HUMAN 1 1107.5924 0.02 29349 13351 2 1107.58904 554.8035 Probable ATP-dependent RNA helicase DDX28 OS=Homo sapiens OX=9606 GN=DDX28 PE=1 SV=2 4.37 2598.4 - 2.70E+06 - - - -3.0553 - 2.192 0.446 - 501.7 1 2 0 -0.0034 10 0 0 0 8.65E+07 3.58E+09 - - - 4.5247 0.9002 221125_WJC_METTL3_EV_vs_WT_F03.13355.13355.2 7.71 14-Jul K.VWNLANC[160.03]K.L "sp|P63244|RACK1_HUMAN,tr|H0YAM7|H0YAM7_HUMAN,tr|D6RFX4|D6RFX4_HUMAN,tr|D6R9Z1|D6R9Z1_HUMAN,tr|J3KPE3|J3KPE3_HUMAN,tr|D6R9L0|D6R9L0_HUMAN,tr|D6RHH4|D6RHH4_HUMAN,tr|D6RBD0|D6RBD0_HUMAN,tr|D6RAC2|D6RAC2_HUMAN,tr|H0Y8R5|H0Y8R5_HUMAN,tr|D6REE5|D6REE5_HUMAN,tr|H0Y8W2|H0Y8W2_HUMAN" 12 1003.4909 0.65 29351 13355 2 1003.494156 502.7527 Receptor of activated protein C kinase 1 OS=Homo sapiens OX=9606 GN=RACK1 PE=1 SV=3 8.19 2598.9 - 3.55E+06 - - - 3.2088 - 1.178 0.083 - 139.6 1 2 0 0.0032 8 0 0 0 2.14E+08 3.27E+08 - - - 0.1471 0.9995 221125_WJC_METTL3_EV_vs_WT_F03.13356.13356.2 0.18 14-Aug R.QTVLESIR.T "sp|Q5T9A4|ATD3B_HUMAN,sp|Q9NVI7|ATD3A_HUMAN,tr|A0A5K1VW56|A0A5K1VW56_HUMAN" 3 944.5291 1.25 29352 13356 2 944.529845 473.2718 ATPase family AAA domain-containing protein 3B OS=Homo sapiens OX=9606 GN=ATAD3B PE=1 SV=1 6 2598.9 - 2.79E+06 - - - 0.794 - 1.654 0.348 - 277.3 1 2 0 0.0008 8 0 0 0 9.78E+07 7.84E+07 - - - 3.1287 0.9993 221125_WJC_METTL3_EV_vs_WT_F03.13357.13357.2 0.0111 13/22 R.GEPPLPEEDLSK[136.11].L "sp|O15372|EIF3H_HUMAN,tr|B3KS98|B3KS98_HUMAN,tr|A0A087WZK9|A0A087WZK9_HUMAN" 3 1317.6544 2.18 29353 13357 2 1317.652538 659.8345 Eukaryotic translation initiation factor 3 subunit H OS=Homo sapiens OX=9606 GN=EIF3H PE=1 SV=1 4 2599.1 - 1.71E+06 - - - -1.3843 - 1.784 0.337 - 416.3 1 2 0 -0.0018 12 0 0 0 1.32E+08 6.04E+07 - - - 3.0526 0.9989 221125_WJC_METTL3_EV_vs_WT_F03.13358.13358.3 0.00983 Sep-36 K.FVMKPPQVVR.V sp|P20042|IF2B_HUMAN 1 1199.6849 1.28 29354 13358 3 1199.684627 400.9022 Eukaryotic translation initiation factor 2 subunit 2 OS=Homo sapiens OX=9606 GN=EIF2S2 PE=1 SV=2 11 2599.2 - 1.22E+06 - - - -0.2151 - 1.639 0.291 - 91.9 1 2 0 -0.0003 10 0 0 0 1.14E+08 8.92E+07 - - - 3.2272 0.9995 221125_WJC_METTL3_EV_vs_WT_F03.13364.13364.2 0.00307 16-Aug K.QQQVDIPLR[166.11].L sp|Q9NZI8|IF2B1_HUMAN 1 1105.6119 1.82 29358 13364 2 1105.609731 553.8132 Insulin-like growth factor 2 mRNA-binding protein 1 OS=Homo sapiens OX=9606 GN=IGF2BP1 PE=1 SV=2 5.84 2600 - 3.22E+06 - - - -1.9862 - 1.665 0.455 - 350.6 1 2 0 -0.0022 9 0 0 0 1.38E+08 7.59E+07 - - - 3.8759 0.9996 221125_WJC_METTL3_EV_vs_WT_F03.13365.13365.2 0.000581 20-Jul K.NPNGPYPYTLK.L "sp|P14866|HNRPL_HUMAN,tr|A0A3B3ITJ4|A0A3B3ITJ4_HUMAN,tr|M0QXS5|M0QXS5_HUMAN" 3 1262.6295 1.3 29359 13365 2 1262.628309 632.322 Heterogeneous nuclear ribonucleoprotein L OS=Homo sapiens OX=9606 GN=HNRNPL PE=1 SV=2 8.5 2600.1 - 877177 - - - -0.9734 - 1.662 0.393 - 162.5 1 2 0 -0.0012 11 0 0 0 4.22E+08 3.25E+08 - - - 3.3176 0.9796 221125_WJC_METTL3_EV_vs_WT_F03.13366.13366.2 0.0233 18-Oct N.PEAALSPTFR[166.11].S "sp|Q86U44|MTA70_HUMAN,tr|B4E349|B4E349_HUMAN,tr|F5H6D8|F5H6D8_HUMAN,tr|B4DTN4|B4DTN4_HUMAN" 4 1097.5745 0 29360 13366 2 1097.572397 549.7945 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 6.43 2600.1 - 4.92E+06 - - - -1.8969 - 2.163 0.419 - 566.3 1 1 0 -0.0021 10 0 0 0 9.39E+04 1.14E+08 - - - 4.2886 0.8908 221125_WJC_METTL3_EV_vs_WT_F03.13367.13367.2 3.95 12-Jul A.LTGLLHR[166.11].T "sp|P55084|ECHB_HUMAN,tr|C9JE81|C9JE81_HUMAN,tr|B5MD38|B5MD38_HUMAN,tr|C9JEY0|C9JEY0_HUMAN" 4 818.5002 0.7 29361 13367 2 818.499799 410.2574 "Trifunctional enzyme subunit beta, mitochondrial OS=Homo sapiens OX=9606 GN=HADHB PE=1 SV=3" 9.76 2600.3 - 1.44E+06 - - - -0.4801 - 1.693 0.147 - 158 1 1 0 -0.0004 7 0 0 0 1.55E+07 2.22E+07 - - - 1.7949 0.9995 221125_WJC_METTL3_EV_vs_WT_F03.13371.13371.2 0.00186 16-Sep K.DATLTALDR[166.11].G "sp|P40939|ECHA_HUMAN,tr|A0A2R8YG21|A0A2R8YG21_HUMAN,tr|H0YFD6|H0YFD6_HUMAN,tr|A0A2R8Y4F5|A0A2R8Y4F5_HUMAN" 4 984.5115 0.24 29364 13371 2 984.509314 493.263 "Trifunctional enzyme subunit alpha, mitochondrial OS=Homo sapiens OX=9606 GN=HADHA PE=1 SV=2" 4.21 2600.7 - 2.76E+06 - - - -2.2661 - 2.067 0.416 - 299 1 2 0 -0.0022 9 0 0 0 2.24E+07 9.50E+07 - - - 4.2135 0.9997 221125_WJC_METTL3_EV_vs_WT_F03.13373.13373.2 0.006 16-Aug K.QQQVDIPLR.L sp|Q9NZI8|IF2B1_HUMAN 1 1095.6037 1.83 29365 13373 2 1095.603609 548.8091 Insulin-like growth factor 2 mRNA-binding protein 1 OS=Homo sapiens OX=9606 GN=IGF2BP1 PE=1 SV=2 5.84 2600.9 - 4.90E+06 - - - -0.0438 - 1.777 0.415 - 388.1 1 2 0 0 9 0 0 0 1.39E+08 7.59E+07 - - - 3.7695 1 221125_WJC_METTL3_EV_vs_WT_F03.13375.13375.2 1.63E-08 20-Dec K.NPNGPYPYTLK[136.11].L "sp|P14866|HNRPL_HUMAN,tr|A0A3B3ITJ4|A0A3B3ITJ4_HUMAN,tr|M0QXS5|M0QXS5_HUMAN" 3 1270.6437 1.3 29367 13375 2 1270.642625 636.3291 Heterogeneous nuclear ribonucleoprotein L OS=Homo sapiens OX=9606 GN=HNRNPL PE=1 SV=2 8.5 2601.2 - 1.26E+06 - - - -0.8759 - 2.588 0.607 - 541.9 1 2 0 -0.0011 11 0 0 0 4.21E+08 3.24E+08 - - - 6.0963 0.984 221125_WJC_METTL3_EV_vs_WT_F03.13377.13377.2 0.289 18-Sep K.EVLPALENNK[136.11].E sp|Q9UHV9|PFD2_HUMAN 1 1133.6172 4.7 29369 13377 2 1133.613378 567.8159 Prefoldin subunit 2 OS=Homo sapiens OX=9606 GN=PFDN2 PE=1 SV=1 4.53 2601.4 - 604720 - - - -3.3618 - 1.653 0.148 - 188.1 1 2 0 -0.0038 10 0 0 0 2.33E+08 4.95E+07 - - - 1.5358 0.8265 221125_WJC_METTL3_EV_vs_WT_F03.13380.13380.2 0.731 16-Aug K.VEFLEC[160.03]SAK[136.11].G "sp|Q9Y5M8|SRPRB_HUMAN,tr|H7C4H2|H7C4H2_HUMAN" 2 1089.5256 0.43 29370 13380 2 1089.531849 545.7701 Signal recognition particle receptor subunit beta OS=Homo sapiens OX=9606 GN=SRPRB PE=1 SV=3 4.53 2601.8 - 2.24E+06 - - - 5.7383 - 1.496 0.099 - 245.4 1 2 0 0.0063 9 0 0 0 2.84E+07 6.62E+07 - - - 0.9356 0.9999 221125_WJC_METTL3_EV_vs_WT_F03.13382.13382.2 0.000217 18-Dec K.MADEAILQER[166.11].E sp|Q9HCD5|NCOA5_HUMAN 1 1184.5735 1.35 29372 13382 2 1184.573777 593.294 Nuclear receptor coactivator 5 OS=Homo sapiens OX=9606 GN=NCOA5 PE=1 SV=2 4.14 2602 - 5.25E+06 - - - 0.2397 - 2.539 0.454 - 764.4 1 2 0 0.0003 10 0 0 0 1.82E+08 1.35E+08 - - - 4.995 0.9993 221125_WJC_METTL3_EV_vs_WT_F03.13383.13383.2 0.00411 16-Jul K.GITYDDPIK[136.11].T "sp|Q9UJV9|DDX41_HUMAN,tr|A0A499FJW5|A0A499FJW5_HUMAN,tr|H0YA06|H0YA06_HUMAN,tr|D6RGI7|D6RGI7_HUMAN" 4 1028.527 0.83 29373 13383 2 1028.525714 515.2708 Probable ATP-dependent RNA helicase DDX41 OS=Homo sapiens OX=9606 GN=DDX41 PE=1 SV=2 4.21 2602 - 3.41E+06 - - - -1.228 - 1.424 0.4 - 138.4 1 2 0 -0.0013 9 0 0 0 9.78E+07 1.18E+08 - - - 3.0176 0.9769 221125_WJC_METTL3_EV_vs_WT_F03.13385.13385.2 5.76 14-Jul K.ENVTIMVK.S "sp|Q9HBG7|LY9_HUMAN,tr|Q5VYH9|Q5VYH9_HUMAN,tr|A0A0C4DFU4|A0A0C4DFU4_HUMAN" 3 932.5001 1.34 29375 13385 2 932.499446 467.2573 T-lymphocyte surface antigen Ly-9 OS=Homo sapiens OX=9606 GN=LY9 PE=1 SV=3 6.1 2602.3 - 1.18E+06 - - - -0.7046 - 1.161 0.084 - 191.1 1 2 0 -0.0007 8 0 0 0 2.74E+07 2.05E+07 - - - 0.1114 0.8095 221125_WJC_METTL3_EV_vs_WT_F03.13386.13386.2 5.57 12-Jul R.K[136.11]IELFGR[166.11].P sp|Q86U44|MTA70_HUMAN 1 879.5297 0.001 29376 13386 2 879.529538 440.7721 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 8.75 2602.4 - 1.65E+06 - - - -0.1933 - 1.5 0.129 - 95.3 1 1 0 -0.0002 7 0 0 0 0.00E+00 1.55E+07 - - - 1.2785 0.9993 221125_WJC_METTL3_EV_vs_WT_F03.13389.13389.2 0.0023 16-Sep K.GVTC[160.03]LSFSK.D sp|Q2TAY7|SMU1_HUMAN 1 997.4903 0.47 29377 13389 2 997.490278 499.7524 WD40 repeat-containing protein SMU1 OS=Homo sapiens OX=9606 GN=SMU1 PE=1 SV=2 8.22 2602.8 - 1.23E+06 - - - 0.011 - 1.588 0.306 - 261.2 1 2 0 0 9 0 0 0 1.96E+07 4.17E+07 - - - 2.6391 0.9998 221125_WJC_METTL3_EV_vs_WT_F03.13395.13395.2 0.000235 16-Aug R.GYFSEEMNR.V "sp|Q15149|PLEC_HUMAN,tr|H0YDN1|H0YDN1_HUMAN" 2 1131.4655 1.77 29381 13395 2 1131.466013 566.74 Plectin OS=Homo sapiens OX=9606 GN=PLEC PE=1 SV=3 4.53 2603.5 - 822727 - - - 0.4454 - 1.691 0.489 - 224.6 1 2 0 0.0005 9 0 0 0 1.24E+07 6.99E+06 - - - 4.1724 0.9999 221125_WJC_METTL3_EV_vs_WT_F03.13400.13400.2 2.22E-05 13/22 K.NAGVEGSLIVEK.L "sp|P10809|CH60_HUMAN,tr|A0A7I2V2X6|A0A7I2V2X6_HUMAN,tr|A0A7I2YQK6|A0A7I2YQK6_HUMAN,tr|A0A7I2V599|A0A7I2V599_HUMAN" 4 1214.6507 1.33 29385 13400 2 1214.650258 608.3326 "60 kDa heat shock protein, mitochondrial OS=Homo sapiens OX=9606 GN=HSPD1 PE=1 SV=2" 4.53 2604.1 - 9.62E+06 - - - -0.3367 - 2.601 0.51 - 539.2 1 2 0 -0.0004 12 0 0 0 2.71E+10 2.04E+10 - - - 5.3229 0.9999 221125_WJC_METTL3_EV_vs_WT_F03.13401.13401.2 1.31E-05 22-Oct K.NAGVEGSLIVEK[136.11].L "sp|P10809|CH60_HUMAN,tr|A0A7I2V2X6|A0A7I2V2X6_HUMAN,tr|A0A7I2YQK6|A0A7I2YQK6_HUMAN,tr|A0A7I2V599|A0A7I2V599_HUMAN" 4 1222.6649 1.33 29386 13401 2 1222.663902 612.3397 "60 kDa heat shock protein, mitochondrial OS=Homo sapiens OX=9606 GN=HSPD1 PE=1 SV=2" 4.53 2604.1 - 6.01E+06 - - - -0.7893 - 1.992 0.518 - 324.5 1 2 0 -0.001 12 0 0 0 2.71E+10 2.04E+10 - - - 4.6799 0.9996 221125_WJC_METTL3_EV_vs_WT_F03.13402.13402.3 0.002 13/40 R.VVDLMAHMASK.E "sp|P04406|G3P_HUMAN,tr|E7EUT5|E7EUT5_HUMAN" 2 1200.5995 0.99 29387 13402 3 1200.599006 401.2071 Glyceraldehyde-3-phosphate dehydrogenase OS=Homo sapiens OX=9606 GN=GAPDH PE=1 SV=3 6.71 2604.2 - 1.83E+06 - - - -0.4115 - 1.733 0.344 - 148.8 1 2 0 -0.0005 11 0 0 0 1.58E+09 1.59E+09 - - - 3.9372 0.9998 221125_WJC_METTL3_EV_vs_WT_F03.13405.13405.2 0.000165 20-Oct R.ELDESLQVAER.L "sp|P10909|CLUS_HUMAN,tr|H0YAS8|H0YAS8_HUMAN,tr|H0YC35|H0YC35_HUMAN" 3 1287.6307 29.25 29390 13405 2 1287.631281 644.8226 Clusterin OS=Homo sapiens OX=9606 GN=CLU PE=1 SV=1 4 2604.5 - 790825 - - - 0.4823 - 2.205 0.456 - 442.2 1 2 0 0.0006 11 0 0 0 1.78E+08 6.09E+06 - - - 4.5479 0.9997 221125_WJC_METTL3_EV_vs_WT_F03.13408.13408.3 0.00952 Oct-32 R.GLLEFEHQR[166.11].A "sp|Q14697|GANAB_HUMAN,tr|E9PNH1|E9PNH1_HUMAN,tr|E9PKU7|E9PKU7_HUMAN,tr|F5H6X6|F5H6X6_HUMAN" 4 1137.5806 0.001 29393 13408 3 1137.581039 380.2008 Neutral alpha-glucosidase AB OS=Homo sapiens OX=9606 GN=GANAB PE=1 SV=3 5.4 2604.9 - 511872 - - - 0.3622 - 2.054 0.324 - 112.2 1 2 0 0.0004 9 0 0 0 0.00E+00 8.57E+06 - - - 4.3215 0.9994 221125_WJC_METTL3_EV_vs_WT_F03.13411.13411.2 0.00231 18-Oct K.VNPIQGLASK.W sp|P13073|COX41_HUMAN 1 1025.5869 0.81 29394 13411 2 1025.588199 513.8007 "Cytochrome c oxidase subunit 4 isoform 1, mitochondrial OS=Homo sapiens OX=9606 GN=COX4I1 PE=1 SV=1" 8.72 2605.3 - 7.35E+06 - - - 1.2227 - 1.853 0.336 - 298.4 1 2 0 0.0013 10 0 0 0 3.99E+08 4.95E+08 - - - 3.244 1 221125_WJC_METTL3_EV_vs_WT_F03.13413.13413.3 2.10E-06 15/40 R.VVDLMAHMASK[136.11].E "sp|P04406|G3P_HUMAN,tr|E7EUT5|E7EUT5_HUMAN" 2 1208.6137 0.99 29396 13413 3 1208.613584 403.8785 Glyceraldehyde-3-phosphate dehydrogenase OS=Homo sapiens OX=9606 GN=GAPDH PE=1 SV=3 6.71 2605.4 - 6.67E+06 - - - -0.096 - 2.562 0.505 - 321.6 1 2 0 -0.0001 11 0 0 0 1.60E+09 1.62E+09 - - - 6.8428 0.9999 221125_WJC_METTL3_EV_vs_WT_F03.13415.13415.2 1.16E-06 13/20 R.QGVDADINGLR.Q "sp|P35527|K1C9_HUMAN,tr|K7EQQ3|K7EQQ3_HUMAN" 2 1156.5837 38.6 29398 13415 2 1156.585237 579.2991 "Keratin, type I cytoskeletal 9 OS=Homo sapiens OX=9606 GN=KRT9 PE=1 SV=3" 4.21 2605.5 - 1.78E+06 - - - 1.3721 - 2.553 0.546 - 854.9 1 2 0 0.0016 11 0 0 0 8.99E+07 2.33E+06 - - - 5.6088 0.9981 221125_WJC_METTL3_EV_vs_WT_F03.13416.13416.2 5.78E-05 20-Nov K.LSAMMGAVAEK[136.11].K "sp|Q86U44|MTA70_HUMAN,tr|F5H6D8|F5H6D8_HUMAN,tr|H0YFV6|H0YFV6_HUMAN,tr|B4DTN4|B4DTN4_HUMAN" 4 1114.5606 0.1 29399 13416 2 1114.566045 558.2876 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 6 2605.6 - 1.30E+06 - - - 4.8835 - 2.319 0.523 - 319.7 1 2 0 0.0054 11 0 0 0 2.65E+07 2.78E+08 - - - 5.1776 0.8911 221125_WJC_METTL3_EV_vs_WT_F03.13418.13418.2 0.178 20-Aug K.VQAGDVITIDK[136.11].A "sp|Q9Y230|RUVB2_HUMAN,tr|M0R0Y3|M0R0Y3_HUMAN" 2 1165.6434 2.05 29401 13418 2 1165.649379 583.829 RuvB-like 2 OS=Homo sapiens OX=9606 GN=RUVBL2 PE=1 SV=3 4.21 2605.8 - 879326 - - - 5.1268 - 1.326 0.165 - 134 1 2 0 0.006 11 0 0 0 4.48E+07 2.19E+07 - - - 1.0211 0.9956 221125_WJC_METTL3_EV_vs_WT_F03.13419.13419.2 0.0578 18-Aug R.SLPGLASSVK[136.11].E sp|Q9NUL7|DDX28_HUMAN 1 965.5637 1.25 29402 13419 2 965.564242 483.7891 Probable ATP-dependent RNA helicase DDX28 OS=Homo sapiens OX=9606 GN=DDX28 PE=1 SV=2 8.47 2605.9 - 598526 - - - 0.5655 - 1.313 0.198 - 127.7 1 2 0 0.0005 10 0 0 0 1.75E+07 1.40E+07 - - - 1.2634 0.9998 221125_WJC_METTL3_EV_vs_WT_F03.13421.13421.2 0.000749 13/22 R.GEPPLPEEDLSK.L "sp|O15372|EIF3H_HUMAN,tr|B3KS98|B3KS98_HUMAN,tr|A0A087WZK9|A0A087WZK9_HUMAN" 3 1309.6402 2.16 29403 13421 2 1309.640678 655.8274 Eukaryotic translation initiation factor 3 subunit H OS=Homo sapiens OX=9606 GN=EIF3H PE=1 SV=1 4 2606.1 - 3.30E+06 - - - 0.394 - 2.196 0.438 - 367.1 1 2 0 0.0005 12 0 0 0 1.37E+08 6.34E+07 - - - 4.3457 0.9988 221125_WJC_METTL3_EV_vs_WT_F03.13423.13423.2 0.689 18-Aug K.VNPIQGLASK[136.11].W sp|P13073|COX41_HUMAN 1 1033.6011 1.3 29404 13423 2 1033.600745 517.8078 "Cytochrome c oxidase subunit 4 isoform 1, mitochondrial OS=Homo sapiens OX=9606 GN=COX4I1 PE=1 SV=1" 8.72 2606.3 - 7.60E+06 - - - -0.387 - 1.656 0.242 - 208.8 1 2 0 -0.0004 10 0 0 0 3.58E+08 2.76E+08 - - - 2.2362 0.9997 221125_WJC_METTL3_EV_vs_WT_F03.13424.13424.2 0.000232 16-Oct R.VQGFQVEYK.D "sp|O95793|STAU1_HUMAN,tr|Q5JW30|Q5JW30_HUMAN" 2 1096.5553 2.36 29405 13424 2 1096.555839 549.2849 Double-stranded RNA-binding protein Staufen homolog 1 OS=Homo sapiens OX=9606 GN=STAU1 PE=1 SV=2 5.97 2606.4 - 6.63E+06 - - - 0.4824 - 1.736 0.433 - 527.3 1 2 0 0.0005 9 0 0 0 3.08E+08 1.30E+08 - - - 3.8347 0.9989 221125_WJC_METTL3_EV_vs_WT_F03.13427.13427.2 1.24E-05 20-Oct R.VYGAPQLQVEK[136.11].V sp|P26572|MGAT1_HUMAN 1 1238.675 2.11 29408 13427 2 1238.679081 620.3448 "Alpha-1,3-mannosyl-glycoprotein 2-beta-N-acetylglucosaminyltransferase OS=Homo sapiens OX=9606 GN=MGAT1 PE=1 SV=2" 5.97 2606.6 - 810426 - - - 3.264 - 1.888 0.453 - 267.6 1 2 0 0.004 11 0 0 0 4.18E+07 1.99E+07 - - - 4.1048 0.9998 221125_WJC_METTL3_EV_vs_WT_F03.13428.13428.2 0.00362 18-Nov R.NSLPDTVQIR[166.11].R "sp|P56537|IF6_HUMAN,tr|B7ZBH1|B7ZBH1_HUMAN" 2 1151.6174 1.88 29409 13428 2 1151.616371 576.816 Eukaryotic translation initiation factor 6 OS=Homo sapiens OX=9606 GN=EIF6 PE=1 SV=1 5.84 2606.7 - 762401 - - - -0.8996 - 2.248 0.378 - 457.3 1 2 0 -0.001 10 0 0 0 2.12E+08 1.13E+08 - - - 4.0937 0.9998 221125_WJC_METTL3_EV_vs_WT_F03.13430.13430.2 1.02E-06 22-Dec R.VFVVGTEAEAC[160.03]R.E sp|Q9H7N4|SFR19_HUMAN 1 1336.6445 0.77 29411 13430 2 1336.646233 669.3295 "Splicing factor, arginine\serine-rich 19 OS=Homo sapiens OX=9606 GN=SCAF1 PE=1 SV=3" 4.53 2606.9 - 562825 - - - 1.2696 - 2.163 0.525 - 497.4 1 2 0 0.0017 12 0 0 0 2.70E+07 3.49E+07 - - - 4.9481 0.9995 221125_WJC_METTL3_EV_vs_WT_F03.13436.13436.2 0.00123 18-Aug R.LDDMSSIVQK.A "sp|Q9UBU9|NXF1_HUMAN,tr|B4E227|B4E227_HUMAN,tr|E9PIN3|E9PIN3_HUMAN" 3 1134.5591 1.62 29415 13436 2 1134.558392 568.2868 Nuclear RNA export factor 1 OS=Homo sapiens OX=9606 GN=NXF1 PE=1 SV=1 4.21 2607.7 - 2.67E+06 - - - -0.602 - 1.846 0.328 - 186 1 2 0 -0.0007 10 0 0 0 2.48E+08 1.54E+08 - - - 3.1745 0.9977 221125_WJC_METTL3_EV_vs_WT_F03.13437.13437.2 0.141 20-Jul R.VYGAPQLQVEK.V sp|P26572|MGAT1_HUMAN 1 1230.6608 2.09 29416 13437 2 1230.660341 616.3377 "Alpha-1,3-mannosyl-glycoprotein 2-beta-N-acetylglucosaminyltransferase OS=Homo sapiens OX=9606 GN=MGAT1 PE=1 SV=2" 5.97 2607.8 - 1.12E+06 - - - -0.4038 - 1.327 0.256 - 101.3 1 2 0 -0.0005 11 0 0 0 4.15E+07 1.99E+07 - - - 1.697 0.9947 221125_WJC_METTL3_EV_vs_WT_F03.13439.13439.2 0.00201 20-Aug R.VIC[160.03]AEEPYIC[160.03]K[136.11].D sp|P49915|GUAA_HUMAN 1 1388.656 1.23 29418 13439 2 1388.661617 695.3353 GMP synthase [glutamine-hydrolyzing] OS=Homo sapiens OX=9606 GN=GMPS PE=1 SV=1 4.53 2608.1 - 438402 - - - 4.0744 - 1.614 0.356 - 174.2 1 2 0 0.0057 11 0 0 0 2.34E+07 1.91E+07 - - - 2.9637 0.9997 221125_WJC_METTL3_EV_vs_WT_F03.13443.13443.2 6.63E-06 22-Oct R.AQPSVSLGAPYR.G sp|Q96PK6|RBM14_HUMAN 1 1244.6513 3.76 29421 13443 2 1244.651999 623.3329 RNA-binding protein 14 OS=Homo sapiens OX=9606 GN=RBM14 PE=1 SV=2 8.79 2608.5 - 2.97E+06 - - - 0.5327 - 2.006 0.365 - 354 1 2 0 0.0007 12 0 0 0 2.07E+09 5.49E+08 - - - 3.5684 0.9985 221125_WJC_METTL3_EV_vs_WT_F03.13445.13445.2 0.00167 16-Sep R.VQGFQVEYK[136.11].D "sp|O95793|STAU1_HUMAN,tr|Q5JW30|Q5JW30_HUMAN" 2 1104.5695 2.31 29423 13445 2 1104.566154 553.292 Double-stranded RNA-binding protein Staufen homolog 1 OS=Homo sapiens OX=9606 GN=STAU1 PE=1 SV=2 5.97 2608.7 - 8.09E+06 - - - -3.0383 - 1.714 0.393 - 368.6 1 2 0 -0.0034 9 0 0 0 3.01E+08 1.30E+08 - - - 3.5015 0.9999 221125_WJC_METTL3_EV_vs_WT_F03.13448.13448.2 8.65E-08 24-Nov K.EITEGDEVEVYSR[166.11].A "sp|P51116|FXR2_HUMAN,tr|I3L1Z2|I3L1Z2_HUMAN" 2 1534.7027 0.98 29426 13448 2 1534.704526 768.3586 Fragile X mental retardation syndrome-related protein 2 OS=Homo sapiens OX=9606 GN=FXR2 PE=1 SV=2 3.91 2609.1 - 311725 - - - 1.2204 - 2.286 0.572 - 417.5 1 2 0 0.0019 13 0 0 0 1.71E+07 1.74E+07 - - - 5.3872 0.9749 221125_WJC_METTL3_EV_vs_WT_F03.13451.13451.2 0.105 18-Jun K.GSFLEGSEVR.T sp|P41214|EIF2D_HUMAN 1 1079.5247 1.08 29427 13451 2 1079.526256 540.7696 Eukaryotic translation initiation factor 2D OS=Homo sapiens OX=9606 GN=EIF2D PE=1 SV=3 4.53 2609.4 - 1.53E+06 - - - 1.4062 - 1.292 0.077 - 115.9 1 2 0 0.0015 10 0 0 0 6.69E+07 6.21E+07 - - - 0.3244 0.9993 221125_WJC_METTL3_EV_vs_WT_F03.13452.13452.2 0.00154 16-Oct R.EIGILTTNK.N "sp|Q8IZP0|ABI1_HUMAN,sp|Q9NYB9|ABI2_HUMAN,tr|A0A7D9NKC8|A0A7D9NKC8_HUMAN,tr|A0A0C4DG21|A0A0C4DG21_HUMAN,tr|A0A0A0MRT6|A0A0A0MRT6_HUMAN,tr|E7EW77|E7EW77_HUMAN,tr|E7EP65|E7EP65_HUMAN,tr|F8WAL6|F8WAL6_HUMAN,tr|B6VEX4|B6VEX4_HUMAN,tr|E9PEZ7|E9PEZ7_HUMAN" 10 987.5601 0.96 29428 13452 2 987.560323 494.7873 Abl interactor 1 OS=Homo sapiens OX=9606 GN=ABI1 PE=1 SV=4 6.1 2609.6 - 1.23E+06 - - - 0.2653 - 1.709 0.292 - 293.1 1 2 0 0.0003 9 0 0 0 2.34E+07 2.43E+07 - - - 2.748 0.9999 221125_WJC_METTL3_EV_vs_WT_F03.13454.13454.3 0.00259 14/44 K.LISSDGHEFIVK[136.11].R "sp|Q15369|ELOC_HUMAN,tr|R4GMY8|R4GMY8_HUMAN,tr|E5RHG8|E5RHG8_HUMAN" 3 1351.7227 1.18 29430 13454 3 1351.722497 451.5815 Elongin-C OS=Homo sapiens OX=9606 GN=ELOC PE=1 SV=1 5.32 2609.7 - 1.09E+06 - - - -0.162 - 2.526 0.364 - 254.6 1 2 0 -0.0002 12 0 0 0 2.32E+08 1.96E+08 - - - 5.1667 0.9993 221125_WJC_METTL3_EV_vs_WT_F03.13455.13455.3 0.00116 Oct-40 R.LLVQHEINTLR.A "sp|Q7Z3J3|RGPD4_HUMAN,sp|O14715|RGPD8_HUMAN,sp|P49792|RBP2_HUMAN,sp|A6NKT7|RGPD3_HUMAN,sp|Q99666|RGPD5_HUMAN,tr|F8W705|F8W705_HUMAN,tr|J3KNE0|J3KNE0_HUMAN,tr|J3KQ37|J3KQ37_HUMAN" 8 1334.767 0.65 29431 13455 3 1334.764589 445.9296 RanBP2-like and GRIP domain-containing protein 4 OS=Homo sapiens OX=9606 GN=RGPD4 PE=2 SV=3 6.75 2609.8 - 954362 - - - -1.8318 - 1.978 0.307 - 136.4 1 2 0 -0.0024 11 0 0 0 2.56E+07 3.92E+07 - - - 3.8998 1 221125_WJC_METTL3_EV_vs_WT_F03.13457.13457.2 1.39E-06 13/24 K.EITEGDEVEVYSR.A "sp|P51116|FXR2_HUMAN,tr|I3L1Z2|I3L1Z2_HUMAN" 2 1524.6944 0.98 29433 13457 2 1524.694393 763.3545 Fragile X mental retardation syndrome-related protein 2 OS=Homo sapiens OX=9606 GN=FXR2 PE=1 SV=2 3.91 2610.1 - 376581 - - - 0.0066 - 2.542 0.627 - 631.4 1 2 0 0 13 0 0 0 1.71E+07 1.74E+07 - - - 6.0665 0.9893 221125_WJC_METTL3_EV_vs_WT_F03.13461.13461.2 3.90E-05 16-Nov V.DLMAHMASK.E "sp|P04406|G3P_HUMAN,tr|E7EUT5|E7EUT5_HUMAN" 2 1002.4627 1.02 29435 13461 2 1002.462443 502.2386 Glyceraldehyde-3-phosphate dehydrogenase OS=Homo sapiens OX=9606 GN=GAPDH PE=1 SV=3 6.74 2610.6 - 5.29E+06 - - - -0.2284 - 1.803 0.471 - 366.5 1 1 0 -0.0002 9 0 0 0 1.15E+08 1.13E+08 - - - 4.2251 0.9994 221125_WJC_METTL3_EV_vs_WT_F03.13463.13463.2 0.0223 14-Aug K.DAQIFIQK.K sp|P04040|CATA_HUMAN 1 961.5233 2.53 29437 13463 2 961.522874 481.7689 Catalase OS=Homo sapiens OX=9606 GN=CAT PE=1 SV=3 5.84 2610.7 - 2.56E+06 - - - -0.4243 - 1.657 0.304 - 305.4 1 2 0 -0.0004 8 0 0 0 5.67E+07 2.24E+07 - - - 2.8093 0.9952 221125_WJC_METTL3_EV_vs_WT_F03.13464.13464.2 0.273 22-Sep K.WVPAGGSTGFSR[166.11].V "sp|Q8N8S7|ENAH_HUMAN,tr|A0A075B6E5|A0A075B6E5_HUMAN,tr|A0A0U1RRM6|A0A0U1RRM6_HUMAN" 3 1230.6021 2.3 29438 13464 2 1230.60026 616.3083 Protein enabled homolog OS=Homo sapiens OX=9606 GN=ENAH PE=1 SV=2 9.75 2610.7 - 1.62E+06 - - - -1.4879 - 1.265 0.242 - 214.5 1 2 0 -0.0018 12 0 0 0 9.67E+07 4.21E+07 - - - 1.4464 0.9943 221125_WJC_METTL3_EV_vs_WT_F03.13465.13465.3 0.105 Oct-36 K.FVMK[136.11]PPQVVR[166.11].V sp|P20042|IF2B_HUMAN 1 1217.7074 1.3 29439 13465 3 1217.706283 406.9097 Eukaryotic translation initiation factor 2 subunit 2 OS=Homo sapiens OX=9606 GN=EIF2S2 PE=1 SV=2 11 2610.8 - 1.53E+06 - - - -0.8803 - 1.551 0.209 - 137.4 1 2 0 -0.0011 10 0 0 0 1.16E+08 8.95E+07 - - - 2.1516 0.9998 221125_WJC_METTL3_EV_vs_WT_F03.13468.13468.2 1.88E-05 18-Oct K.NGQDLGVAFK[136.11].L "sp|Q00839|HNRPU_HUMAN,tr|A0A1W2PQL0|A0A1W2PQL0_HUMAN,tr|A0A1W2PPL4|A0A1W2PPL4_HUMAN,tr|A0A1W2PQ74|A0A1W2PQ74_HUMAN,tr|Q5RI18|Q5RI18_HUMAN,tr|A0A1W2PP35|A0A1W2PP35_HUMAN,tr|A0A1W2PPS1|A0A1W2PPS1_HUMAN,tr|A0A1W2PRZ7|A0A1W2PRZ7_HUMAN,tr|A0A1W2PPH7|A0A1W2PPH7_HUMAN,tr|A0A1W2PP34|A0A1W2PP34_HUMAN,tr|A0A1X7SBS1|A0A1X7SBS1_HUMAN" 11 1055.5491 1.01 29442 13468 2 1055.548521 528.7818 Heterogeneous nuclear ribonucleoprotein U OS=Homo sapiens OX=9606 GN=HNRNPU PE=1 SV=6 5.84 2611.1 - 1.13E+06 - - - -0.5571 - 1.896 0.478 - 360.6 1 2 0 -0.0006 10 0 0 0 5.59E+09 5.56E+09 - - - 4.3571 0.9989 221125_WJC_METTL3_EV_vs_WT_F03.13476.13476.2 0.0178 18-Aug K.EVPAVPETLK[136.11].K sp|P18124|RL7_HUMAN 1 1089.6161 1.35 29448 13476 2 1089.615739 545.8153 60S ribosomal protein L7 OS=Homo sapiens OX=9606 GN=RPL7 PE=1 SV=1 4.53 2611.9 - 2.29E+06 - - - -0.3552 - 1.368 0.325 - 231.7 1 2 0 -0.0004 10 0 0 0 3.16E+08 2.34E+08 - - - 2.316 0.9996 221125_WJC_METTL3_EV_vs_WT_F03.13477.13477.2 0.00643 14-Oct K.TVEFLNEK.L "sp|P82094|TMF1_HUMAN,tr|F8WF45|F8WF45_HUMAN,tr|A0A2R8Y7M0|A0A2R8Y7M0_HUMAN" 3 978.5022 1.37 29449 13477 2 978.500632 490.2584 TATA element modulatory factor OS=Homo sapiens OX=9606 GN=TMF1 PE=1 SV=2 4.53 2612 - 1.92E+06 - - - -1.6147 - 1.823 0.387 - 270 1 2 0 -0.0016 8 0 0 0 1.93E+08 1.40E+08 - - - 3.7099 0.9985 221125_WJC_METTL3_EV_vs_WT_F03.13488.13488.3 0.0422 Oct-40 K.VTLEYR[166.11]PVIDK[136.11].T "sp|P31040|SDHA_HUMAN,tr|A0A087X1I3|A0A087X1I3_HUMAN,tr|D6RFM5|D6RFM5_HUMAN" 3 1349.7674 1.17 29457 13488 3 1349.766607 450.9297 "Succinate dehydrogenase [ubiquinone] flavoprotein subunit, mitochondrial OS=Homo sapiens OX=9606 GN=SDHA PE=1 SV=2" 6.04 2613.3 - 2.58E+06 - - - -0.5668 - 2.23 0.2 - 151.6 1 2 0 -0.0008 11 0 0 0 4.90E+07 4.18E+07 - - - 3.0479 0.9528 221125_WJC_METTL3_EV_vs_WT_F03.13491.13491.2 0.181 12-Jul R.MLVELSK[136.11].A sp|P50991|TCPD_HUMAN 1 826.4714 0.54 29459 13491 2 826.467333 414.243 T-complex protein 1 subunit delta OS=Homo sapiens OX=9606 GN=CCT4 PE=1 SV=4 5.75 2613.6 - 643451 - - - -4.8919 - 1.493 0.166 - 196.6 1 2 0 -0.004 7 0 0 0 4.99E+06 9.24E+06 - - - 1.5357 0.8257 221125_WJC_METTL3_EV_vs_WT_F03.13492.13492.3 0.238 Sep-40 R.LFDQPGDPLK[136.11]R[166.11].S sp|Q96EY7|PTCD3_HUMAN 1 1302.7051 1.2 29460 13492 3 1302.704312 435.2423 "Pentatricopeptide repeat domain-containing protein 3, mitochondrial OS=Homo sapiens OX=9606 GN=PTCD3 PE=1 SV=3" 5.96 2613.7 - 735293 - - - -0.6095 - 1.627 0.016 - 91.3 1 2 0 -0.0008 11 0 0 0 2.11E+07 1.75E+07 - - - 0.1009 0.9998 221125_WJC_METTL3_EV_vs_WT_F03.13493.13493.2 0.000192 22-Dec R.FLEQQNQVLETK.W "sp|Q86Y46|K2C73_HUMAN,sp|Q7RTS7|K2C74_HUMAN,sp|Q3SY84|K2C71_HUMAN,sp|Q14CN4|K2C72_HUMAN,tr|H0YIG3|H0YIG3_HUMAN,tr|F8W1S1|F8W1S1_HUMAN" 6 1475.762 999 29461 13493 2 1475.759195 738.8883 "Keratin, type II cytoskeletal 73 OS=Homo sapiens OX=9606 GN=KRT73 PE=1 SV=1" 4.53 2613.9 - 400265 - - - -1.9068 - 2.571 0.556 - 399.2 1 2 0 -0.0028 12 0 0 0 2.45E+08 0.00E+00 - - - 5.6313 0.9999 221125_WJC_METTL3_EV_vs_WT_F03.13495.13495.2 8.17E-06 18-Oct K.IMEVDYSVSK.K "sp|Q9Y6M1|IF2B2_HUMAN,tr|F8W930|F8W930_HUMAN" 2 1169.5638 1.1 29462 13495 2 1169.562885 585.7892 Insulin-like growth factor 2 mRNA-binding protein 2 OS=Homo sapiens OX=9606 GN=IGF2BP2 PE=1 SV=2 4.37 2614.1 - 3.20E+06 - - - -0.8046 - 1.995 0.551 - 338.2 1 2 0 -0.0009 10 0 0 0 4.82E+07 4.40E+07 - - - 5.0382 0.9998 221125_WJC_METTL3_EV_vs_WT_F03.13497.13497.2 3.07E-07 18-Dec K.NGQDLGVAFK.L "sp|Q00839|HNRPU_HUMAN,tr|A0A1W2PQL0|A0A1W2PQL0_HUMAN,tr|A0A1W2PPL4|A0A1W2PPL4_HUMAN,tr|A0A1W2PQ74|A0A1W2PQ74_HUMAN,tr|Q5RI18|Q5RI18_HUMAN,tr|A0A1W2PP35|A0A1W2PP35_HUMAN,tr|A0A1W2PPS1|A0A1W2PPS1_HUMAN,tr|A0A1W2PRZ7|A0A1W2PRZ7_HUMAN,tr|A0A1W2PPH7|A0A1W2PPH7_HUMAN,tr|A0A1W2PP34|A0A1W2PP34_HUMAN,tr|A0A1X7SBS1|A0A1X7SBS1_HUMAN" 11 1047.5349 1.01 29463 13497 2 1047.536669 524.7747 Heterogeneous nuclear ribonucleoprotein U OS=Homo sapiens OX=9606 GN=HNRNPU PE=1 SV=6 5.84 2614.3 - 2.39E+07 - - - 1.6801 - 2.548 0.528 - 754.2 1 2 0 0.0018 10 0 0 0 5.59E+09 5.56E+09 - - - 5.551 0.9994 221125_WJC_METTL3_EV_vs_WT_F03.13498.13498.2 0.0184 14-Jun K.DDIENMVK[136.11].N "sp|P38646|GRP75_HUMAN,tr|A0A7I2V2S7|A0A7I2V2S7_HUMAN,tr|A0A7I2V2G2|A0A7I2V2G2_HUMAN,tr|H0Y8S0|H0Y8S0_HUMAN,tr|A0A7I2V3F7|A0A7I2V3F7_HUMAN,tr|A0A7I2YQB2|A0A7I2YQB2_HUMAN,tr|D6RCD7|D6RCD7_HUMAN" 7 970.4521 0.42 29464 13498 2 970.451761 486.2333 "Stress-70 protein, mitochondrial OS=Homo sapiens OX=9606 GN=HSPA9 PE=1 SV=2" 4.03 2614.4 - 5.17E+06 - - - -0.3462 - 1.327 0.409 - 90.2 1 2 0 -0.0003 8 0 0 0 1.05E+08 2.49E+08 - - - 2.915 0.9731 221125_WJC_METTL3_EV_vs_WT_F03.13499.13499.2 0.000249 18-Oct V.VDLMAHMASK.E "sp|P04406|G3P_HUMAN,tr|E7EUT5|E7EUT5_HUMAN" 2 1101.5311 0.8 29465 13499 2 1101.527509 551.7728 Glyceraldehyde-3-phosphate dehydrogenase OS=Homo sapiens OX=9606 GN=GAPDH PE=1 SV=3 6.71 2614.4 - 3.46E+06 - - - -3.2473 - 2.347 0.564 - 374.2 1 1 0 -0.0036 10 0 0 0 7.20E+07 9.02E+07 - - - 5.5869 1 221125_WJC_METTL3_EV_vs_WT_F03.13502.13502.3 1.94E-08 14/44 R.RPIQVMMMGSAR.V "sp|P42771|CDN2A_HUMAN,tr|J3QRG6|J3QRG6_HUMAN" 2 1375.6887 0.73 29468 13502 3 1375.688931 459.5702 Cyclin-dependent kinase inhibitor 2A OS=Homo sapiens OX=9606 GN=CDKN2A PE=1 SV=2 12 2614.7 - 583155 - - - 0.1926 - 2.434 0.574 - 313.9 1 2 0 0.0003 12 0 0 0 1.18E+07 1.62E+07 - - - 7.4051 0.9997 221125_WJC_METTL3_EV_vs_WT_F03.13506.13506.2 6.50E-05 18-Nov K.EVPAVPETLK.K sp|P18124|RL7_HUMAN 1 1081.6019 1.35 29470 13506 2 1081.601739 541.8082 60S ribosomal protein L7 OS=Homo sapiens OX=9606 GN=RPL7 PE=1 SV=1 4.53 2615.2 - 9.36E+06 - - - -0.1729 - 1.636 0.456 - 443.6 1 2 0 -0.0002 10 0 0 0 3.16E+08 2.34E+08 - - - 3.783 0.9987 221125_WJC_METTL3_EV_vs_WT_F03.13507.13507.3 0.706 14/40 K.VTLEYRPVIDK.T "sp|P31040|SDHA_HUMAN,tr|A0A087X1I3|A0A087X1I3_HUMAN,tr|D6RFM5|D6RFM5_HUMAN" 3 1331.7449 1.18 29471 13507 3 1331.744189 444.9222 "Succinate dehydrogenase [ubiquinone] flavoprotein subunit, mitochondrial OS=Homo sapiens OX=9606 GN=SDHA PE=1 SV=2" 6.04 2615.3 - 1.89E+06 - - - -0.5354 - 2.416 0.186 - 250.8 1 2 0 -0.0007 11 0 0 0 4.93E+07 4.18E+07 - - - 3.1195 0.9939 221125_WJC_METTL3_EV_vs_WT_F03.13508.13508.2 0.533 22-Jun K.ETPPPLVPPAAR[166.11].E sp|Q9BQA1|MEP50_HUMAN 1 1253.7007 4.77 29472 13508 2 1253.699584 627.8576 Methylosome protein 50 OS=Homo sapiens OX=9606 GN=WDR77 PE=1 SV=1 6.1 2615.4 - 1.31E+06 - - - -0.9237 - 1.146 0.226 - 85.9 1 2 0 -0.0012 12 0 0 0 1.47E+09 3.08E+08 - - - 1.0684 0.914 221125_WJC_METTL3_EV_vs_WT_F03.13509.13509.3 0.231 Aug-32 R.WYHPGC[160.03]FVK.N "sp|P09874|PARP1_HUMAN,tr|A0A7I2V5E9|A0A7I2V5E9_HUMAN,tr|A0A7I2V625|A0A7I2V625_HUMAN,tr|A0A7I2V3E1|A0A7I2V3E1_HUMAN" 4 1192.5488 1 29473 13509 3 1192.549322 398.5235 Poly [ADP-ribose] polymerase 1 OS=Homo sapiens OX=9606 GN=PARP1 PE=1 SV=4 8.21 2615.5 - 1.01E+06 - - - 0.4503 - 1.565 0.058 - 71.5 1 2 0 0.0005 9 0 0 0 1.13E+08 1.13E+08 - - - 0.5363 0.9994 221125_WJC_METTL3_EV_vs_WT_F03.13512.13512.2 0.0268 22-Aug K.ETPPPLVPPAAR.E sp|Q9BQA1|MEP50_HUMAN 1 1243.6925 5.66 29474 13512 2 1243.692207 622.8535 Methylosome protein 50 OS=Homo sapiens OX=9606 GN=WDR77 PE=1 SV=1 6.1 2616 - 3.87E+06 - - - -0.2131 - 1.6 0.341 - 174.2 1 2 0 -0.0003 12 0 0 0 1.94E+09 3.43E+08 - - - 2.7962 0.9964 221125_WJC_METTL3_EV_vs_WT_F03.13513.13513.2 0.534 16-Aug K.NLQSVVLSK[136.11].M "sp|P43246|MSH2_HUMAN,tr|A0A2R8YG02|A0A2R8YG02_HUMAN,tr|A0A2R8Y7S8|A0A2R8Y7S8_HUMAN,tr|E9PHA6|E9PHA6_HUMAN,tr|A0A2R8YFH0|A0A2R8YFH0_HUMAN,tr|A0A2R8Y6P0|A0A2R8Y6P0_HUMAN" 6 994.5902 0.74 29475 13513 2 994.590451 498.3024 DNA mismatch repair protein Msh2 OS=Homo sapiens OX=9606 GN=MSH2 PE=1 SV=1 8.75 2616 - 1.84E+06 - - - 0.2061 - 1.473 0.162 - 144.1 1 2 0 0.0002 9 0 0 0 3.89E+07 5.24E+07 - - - 1.358 0.9978 221125_WJC_METTL3_EV_vs_WT_F03.13515.13515.2 0.00067 18-Sep K.QSLTMDPVVK.S sp|P34932|HSP74_HUMAN 1 1116.5849 0.05 29477 13515 2 1116.589209 559.2997 Heat shock 70 kDa protein 4 OS=Homo sapiens OX=9606 GN=HSPA4 PE=1 SV=4 5.84 2616.1 - 1.24E+06 - - - 3.8627 - 1.793 0.418 - 227.3 1 2 0 0.0043 10 0 0 0 2.06E+07 3.77E+08 - - - 3.7568 0.9954 221125_WJC_METTL3_EV_vs_WT_F03.13516.13516.2 0.0736 12-Jul K.TNFFGTR[166.11].D "sp|P16152|CBR1_HUMAN,tr|E9PQ63|E9PQ63_HUMAN,tr|A8MTM1|A8MTM1_HUMAN" 3 851.4165 1.01 29478 13516 2 851.415155 426.7155 Carbonyl reductase [NADPH] 1 OS=Homo sapiens OX=9606 GN=CBR1 PE=1 SV=3 9.41 2616.3 - 1.06E+06 - - - -1.6056 - 1.273 0.235 - 289.2 1 2 0 -0.0014 7 0 0 0 1.15E+08 1.15E+08 - - - 1.5411 0.7851 221125_WJC_METTL3_EV_vs_WT_F03.13519.13519.2 0.94 12-Jun R.HFGMLSR.W "sp|Q7L3B6|CD37L_HUMAN,tr|B1AL69|B1AL69_HUMAN" 2 846.417 0.69 29481 13519 2 846.412927 424.2158 Hsp90 co-chaperone Cdc37-like 1 OS=Homo sapiens OX=9606 GN=CDC37L1 PE=1 SV=1 9.76 2616.6 - 190505 - - - -4.8617 - 1.104 0.132 - 74.6 1 2 0 -0.0041 7 0 0 0 4.55E+06 6.61E+06 - - - 0.3282 0.9998 221125_WJC_METTL3_EV_vs_WT_F03.13523.13523.2 0.00263 20-Nov R.LDQQTLPLGGR.E sp|P98175|RBM10_HUMAN 1 1196.6513 2.46 29483 13523 2 1196.651004 599.3329 RNA-binding protein 10 OS=Homo sapiens OX=9606 GN=RBM10 PE=1 SV=3 5.84 2617.1 - 5.40E+06 - - - -0.2774 - 2.589 0.366 - 420.2 1 2 0 -0.0003 11 0 0 0 3.39E+08 1.38E+08 - - - 4.3176 0.9993 221125_WJC_METTL3_EV_vs_WT_F03.13525.13525.2 0.106 14-Sep R.SDLLLSGR.D "sp|O14744|ANM5_HUMAN,tr|C9JSX3|C9JSX3_HUMAN,tr|G3V580|G3V580_HUMAN,tr|G3V2L6|G3V2L6_HUMAN,tr|G3V5L5|G3V5L5_HUMAN" 5 859.4763 2.95 29485 13525 2 859.475925 430.7454 Protein arginine N-methyltransferase 5 OS=Homo sapiens OX=9606 GN=PRMT5 PE=1 SV=4 5.55 2617.3 - 2.03E+06 - - - -0.4724 - 1.763 0.267 - 267 1 2 0 -0.0004 8 0 0 0 9.01E+07 3.06E+07 - - - 2.723 0.9993 221125_WJC_METTL3_EV_vs_WT_F03.13526.13526.2 0.00712 12-Aug K.TNFFGTR.D "sp|P16152|CBR1_HUMAN,tr|E9PQ63|E9PQ63_HUMAN,tr|A8MTM1|A8MTM1_HUMAN" 3 841.4083 1.02 29486 13526 2 841.407595 421.7114 Carbonyl reductase [NADPH] 1 OS=Homo sapiens OX=9606 GN=CBR1 PE=1 SV=3 9.41 2617.4 - 1.52E+06 - - - -0.7808 - 1.465 0.339 - 393.6 1 2 0 -0.0007 7 0 0 0 1.15E+08 1.13E+08 - - - 2.7546 0.9631 221125_WJC_METTL3_EV_vs_WT_F03.13527.13527.3 0.223 Oct-44 K.ETPPPLVPPAAR.E sp|Q9BQA1|MEP50_HUMAN 1 1243.6925 3.14 29487 13527 3 1243.690438 415.5714 Methylosome protein 50 OS=Homo sapiens OX=9606 GN=WDR77 PE=1 SV=1 6.1 2617.5 - 520334 - - - -1.6355 - 2.036 0.077 - 150.2 2 2 0 -0.002 12 0 0 0 1.24E+08 3.96E+07 - - - 1.2293 0.9998 221125_WJC_METTL3_EV_vs_WT_F03.13531.13531.2 0.00498 18-Sep R.NSLPDTVQIR.R "sp|P56537|IF6_HUMAN,tr|B7ZBH1|B7ZBH1_HUMAN" 2 1141.6091 1.91 29490 13531 2 1141.608311 571.8118 Eukaryotic translation initiation factor 6 OS=Homo sapiens OX=9606 GN=EIF6 PE=1 SV=1 5.84 2617.9 - 6.05E+06 - - - -0.7235 - 2.044 0.399 - 287.5 1 2 0 -0.0008 10 0 0 0 2.20E+08 1.15E+08 - - - 3.9833 0.9992 221125_WJC_METTL3_EV_vs_WT_F03.13533.13533.2 0.0741 12-Jul R.VDFSITK[136.11].R "sp|P62995|TRA2B_HUMAN,tr|H7BXF3|H7BXF3_HUMAN,tr|H7C2L4|H7C2L4_HUMAN" 3 816.4473 1.43 29491 13533 2 816.446242 409.2309 Transformer-2 protein homolog beta OS=Homo sapiens OX=9606 GN=TRA2B PE=1 SV=1 5.81 2618.2 - 3.21E+06 - - - -1.2591 - 1.723 0.287 - 149.6 1 2 0 -0.001 7 0 0 0 1.87E+08 1.30E+08 - - - 2.8844 0.9996 221125_WJC_METTL3_EV_vs_WT_F03.13534.13534.2 0.000129 20-Oct R.VVDLMAHMASK.E "sp|P04406|G3P_HUMAN,tr|E7EUT5|E7EUT5_HUMAN" 2 1200.5995 1 29492 13534 2 1200.600748 601.307 Glyceraldehyde-3-phosphate dehydrogenase OS=Homo sapiens OX=9606 GN=GAPDH PE=1 SV=3 6.71 2618.2 - 2.77E+06 - - - 1.0395 - 1.627 0.45 - 252.1 1 2 0 0.0012 11 0 0 0 2.30E+08 2.30E+08 - - - 3.681 0.9514 221125_WJC_METTL3_EV_vs_WT_F03.13538.13538.2 0.0458 16-Aug R.ALENVLSGK.A sp|O43678|NDUA2_HUMAN 1 929.5182 3.51 29496 13538 2 929.521645 465.7664 NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 2 OS=Homo sapiens OX=9606 GN=NDUFA2 PE=1 SV=3 6.05 2618.6 - 438272 - - - 3.7105 - 1.513 0.109 - 168.7 2 2 0 0.0034 9 0 0 0 2.05E+08 5.85E+07 - - - 0.9085 0.9879 221125_WJC_METTL3_EV_vs_WT_F03.13539.13539.3 0.107 Sep-44 K.ETPPPLVPPAAR[166.11].E sp|Q9BQA1|MEP50_HUMAN 1 1253.7007 3.14 29497 13539 3 1253.699603 418.9075 Methylosome protein 50 OS=Homo sapiens OX=9606 GN=WDR77 PE=1 SV=1 6.1 2618.8 - 295235 - - - -0.9085 - 1.786 0.151 - 99.2 2 2 0 -0.0011 12 0 0 0 1.24E+08 3.96E+07 - - - 1.6915 0.9953 221125_WJC_METTL3_EV_vs_WT_F03.13544.13544.2 0.0715 16-Jul K.GLVQALQTK.V "sp|P49327|FAS_HUMAN,tr|A0A0U1RQF0|A0A0U1RQF0_HUMAN" 2 956.5655 0.6 29499 13544 2 956.565795 479.29 Fatty acid synthase OS=Homo sapiens OX=9606 GN=FASN PE=1 SV=3 8.75 2619.4 - 1.90E+06 - - - 0.3283 - 1.533 0.122 - 146.2 1 2 0 0.0003 9 0 0 0 5.63E+07 9.46E+07 - - - 1.178 0.9949 221125_WJC_METTL3_EV_vs_WT_F03.13545.13545.3 0.0493 Dec-36 R.VLAEIPR[166.11]PLK[136.11].R sp|Q8WUF5|IASPP_HUMAN 1 1152.7349 0.07 29500 13545 3 1152.735806 385.2523 RelA-associated inhibitor OS=Homo sapiens OX=9606 GN=PPP1R13L PE=1 SV=4 8.72 2619.5 - 672326 - - - 0.7434 - 1.877 0.165 - 143.7 1 2 0 0.0009 10 0 0 0 1.42E+06 1.92E+07 - - - 2.2183 0.9999 221125_WJC_METTL3_EV_vs_WT_F03.13546.13546.2 8.57E-05 18-Sep R.VSEAYENLVK.S "sp|Q4VCS5|AMOT_HUMAN,tr|A6NP16|A6NP16_HUMAN,tr|E7ERM3|E7ERM3_HUMAN" 3 1150.587 1.47 29501 13546 2 1150.586129 576.3008 Angiomotin OS=Homo sapiens OX=9606 GN=AMOT PE=1 SV=1 4.53 2619.6 - 4.28E+06 - - - -0.7605 - 1.858 0.54 - 326.3 1 2 0 -0.0009 10 0 0 0 7.23E+07 4.92E+07 - - - 4.7584 0.9976 221125_WJC_METTL3_EV_vs_WT_F03.13547.13547.2 0.0215 12-Jul K.GFDEYMK.E sp|Q01469|FABP5_HUMAN 1 888.3688 26.13 29502 13547 2 888.367961 445.1917 Fatty acid-binding protein 5 OS=Homo sapiens OX=9606 GN=FABP5 PE=1 SV=3 4.37 2619.7 - 1.38E+06 - - - -0.8938 - 1.102 0.328 - 151.2 1 2 0 -0.0008 7 0 0 0 2.51E+07 9.62E+05 - - - 1.7711 0.9998 221125_WJC_METTL3_EV_vs_WT_F03.13548.13548.2 3.44E-06 24-Dec R.LLDEEEATDNDLR.A sp|Q8WUM4|PDC6I_HUMAN 1 1531.7002 1.13 29503 13548 2 1531.702422 766.8574 Programmed cell death 6-interacting protein OS=Homo sapiens OX=9606 GN=PDCD6IP PE=1 SV=1 3.71 2619.8 - 499141 - - - 1.4533 - 2.478 0.49 - 561.7 1 2 0 0.0022 13 0 0 0 3.49E+07 3.10E+07 - - - 4.9884 1 221125_WJC_METTL3_EV_vs_WT_F03.13549.13549.2 1.19E-09 13/24 R.LLDEEEATDNDLR[166.11].A sp|Q8WUM4|PDC6I_HUMAN 1 1541.7085 1.13 29504 13549 2 1541.711085 771.8615 Programmed cell death 6-interacting protein OS=Homo sapiens OX=9606 GN=PDCD6IP PE=1 SV=1 3.71 2619.9 - 466366 - - - 1.6988 - 2.655 0.679 - 611.9 1 2 0 0.0026 13 0 0 0 3.49E+07 3.10E+07 - - - 6.5613 0.9995 221125_WJC_METTL3_EV_vs_WT_F03.13552.13552.2 0.00147 18-Oct R.SGNVAELALK.A "sp|P49321|NASP_HUMAN,tr|H0YDS9|H0YDS9_HUMAN,tr|Q5T624|Q5T624_HUMAN,tr|H0YF33|H0YF33_HUMAN,tr|E9PRH9|E9PRH9_HUMAN" 5 1000.5553 999 29505 13552 2 1000.5537 501.2849 Nuclear autoantigenic sperm protein OS=Homo sapiens OX=9606 GN=NASP PE=1 SV=2 5.72 2620.4 - 1.44E+06 - - - -1.6091 - 1.913 0.378 - 311.6 1 2 0 -0.0016 10 0 0 0 4.65E+07 0.00E+00 - - - 3.643 0.9999 221125_WJC_METTL3_EV_vs_WT_F03.13553.13553.2 0.00837 22-Dec R.QLDEGEISTIDK.V sp|P13674|P4HA1_HUMAN 1 1346.6565 1.97 29506 13553 2 1346.65561 674.3355 Prolyl 4-hydroxylase subunit alpha-1 OS=Homo sapiens OX=9606 GN=P4HA1 PE=1 SV=2 3.92 2620.5 - 1.80E+06 - - - -0.6906 - 2.539 0.442 - 661.2 1 2 0 -0.0009 12 0 0 0 5.00E+07 2.54E+07 - - - 4.757 0.9999 221125_WJC_METTL3_EV_vs_WT_F03.13555.13555.2 1.41E-05 24-Dec R.ELAEDGYSGVEVR.V "sp|P23396|RS3_HUMAN,tr|H0YEU2|H0YEU2_HUMAN,tr|E9PL09|E9PL09_HUMAN,tr|E9PK82|E9PK82_HUMAN,tr|F2Z2S8|F2Z2S8_HUMAN,tr|H0YCJ7|H0YCJ7_HUMAN,tr|E9PQ96|E9PQ96_HUMAN,tr|E9PJH4|E9PJH4_HUMAN,tr|E9PPU1|E9PPU1_HUMAN,tr|H0YF32|H0YF32_HUMAN" 10 1422.6627 0.84 29508 13555 2 1422.66254 712.3386 40S ribosomal protein S3 OS=Homo sapiens OX=9606 GN=RPS3 PE=1 SV=2 4 2620.7 - 373327 - - - -0.104 - 2.495 0.468 - 504 1 2 0 -0.0001 13 0 0 0 1.64E+07 1.95E+07 - - - 4.8441 1 221125_WJC_METTL3_EV_vs_WT_F03.13557.13557.3 8.05E-06 14/44 K.LISSDGHEFIVK.R "sp|Q15369|ELOC_HUMAN,tr|R4GMY8|R4GMY8_HUMAN,tr|E5RHG8|E5RHG8_HUMAN" 3 1343.7085 1.19 29509 13557 3 1343.707015 448.9101 Elongin-C OS=Homo sapiens OX=9606 GN=ELOC PE=1 SV=1 5.32 2620.9 - 3.72E+06 - - - -1.1171 - 2.67 0.506 - 231.9 1 2 0 -0.0015 12 0 0 0 2.33E+08 1.96E+08 - - - 6.9032 0.9634 221125_WJC_METTL3_EV_vs_WT_F03.13561.13561.3 0.557 Jul-32 R.WYHPGC[160.03]FVK[136.11].N "sp|P09874|PARP1_HUMAN,tr|A0A7I2V5E9|A0A7I2V5E9_HUMAN,tr|A0A7I2V625|A0A7I2V625_HUMAN,tr|A0A7I2V3E1|A0A7I2V3E1_HUMAN" 4 1200.563 1.04 29512 13561 3 1200.561553 401.1949 Poly [ADP-ribose] polymerase 1 OS=Homo sapiens OX=9606 GN=PARP1 PE=1 SV=4 8.21 2621.2 - 3.72E+06 - - - -1.1928 - 1.285 0.161 - 94.5 1 2 0 -0.0014 9 0 0 0 1.09E+08 1.04E+08 - - - 1.0903 0.9998 221125_WJC_METTL3_EV_vs_WT_F03.13565.13565.2 1.82E-05 18-Sep R.YGGQPLFSEK.F "sp|Q1KMD3|HNRL2_HUMAN,tr|H3BQZ7|H3BQZ7_HUMAN" 2 1124.5502 1.25 29514 13565 2 1124.549662 563.2824 Heterogeneous nuclear ribonucleoprotein U-like protein 2 OS=Homo sapiens OX=9606 GN=HNRNPUL2 PE=1 SV=1 6 2621.7 - 2.27E+06 - - - -0.5006 - 1.634 0.496 - 203.3 1 2 0 -0.0006 10 0 0 0 7.44E+07 5.94E+07 - - - 4.0749 0.9997 221125_WJC_METTL3_EV_vs_WT_F03.13566.13566.2 0.000557 16-Oct K.SFQQLTMEK.E "sp|O75410|TACC1_HUMAN,tr|E7EVI4|E7EVI4_HUMAN,tr|B4E3H6|B4E3H6_HUMAN,tr|H0YAY0|H0YAY0_HUMAN,tr|H0YBT8|H0YBT8_HUMAN,tr|E7ET87|E7ET87_HUMAN" 6 1110.5379 0.9 29515 13566 2 1110.537279 556.2762 Transforming acidic coiled-coil-containing protein 1 OS=Homo sapiens OX=9606 GN=TACC1 PE=1 SV=2 5.72 2621.8 - 2.02E+06 - - - -0.6006 - 1.798 0.396 - 280.1 1 2 0 -0.0007 9 0 0 0 9.37E+07 1.04E+08 - - - 3.6629 0.9991 221125_WJC_METTL3_EV_vs_WT_F03.13567.13567.2 0.0183 16-Oct R.TLYVGNLSR.D "sp|Q01085|TIAR_HUMAN,sp|P31483|TIA1_HUMAN,tr|F8W8I6|F8W8I6_HUMAN,tr|C9JTN7|C9JTN7_HUMAN,tr|E7ETC0|E7ETC0_HUMAN,tr|E5RG67|E5RG67_HUMAN,tr|E5RGV5|E5RGV5_HUMAN" 7 1021.5556 1.66 29516 13567 2 1021.555232 511.7851 Nucleolysin TIAR OS=Homo sapiens OX=9606 GN=TIAL1 PE=1 SV=1 8.41 2621.9 - 3.77E+06 - - - -0.4033 - 1.384 0.341 - 335.4 1 2 0 -0.0004 9 0 0 0 1.87E+08 1.13E+08 - - - 2.4997 0.9998 221125_WJC_METTL3_EV_vs_WT_F03.13571.13571.2 3.54E-05 14-Aug K.DDIENMVK.N "sp|P38646|GRP75_HUMAN,tr|A0A7I2V2S7|A0A7I2V2S7_HUMAN,tr|A0A7I2V2G2|A0A7I2V2G2_HUMAN,tr|H0Y8S0|H0Y8S0_HUMAN,tr|A0A7I2V3F7|A0A7I2V3F7_HUMAN,tr|A0A7I2YQB2|A0A7I2YQB2_HUMAN,tr|D6RCD7|D6RCD7_HUMAN" 7 962.4379 0.42 29519 13571 2 962.436893 482.2262 "Stress-70 protein, mitochondrial OS=Homo sapiens OX=9606 GN=HSPA9 PE=1 SV=2" 4.03 2622.3 - 2.61E+06 - - - -1.0432 - 1.506 0.511 - 215.3 1 2 0 -0.001 8 0 0 0 1.05E+08 2.49E+08 - - - 4.0498 0.9999 221125_WJC_METTL3_EV_vs_WT_F03.13575.13575.3 0.00016 Dec-44 K.LTIHGDLYYEGK[136.11].E "sp|Q13435|SF3B2_HUMAN,tr|E9PPJ0|E9PPJ0_HUMAN,tr|H0YEX5|H0YEX5_HUMAN" 3 1415.7176 1.3 29521 13575 3 1415.716093 472.9132 Splicing factor 3B subunit 2 OS=Homo sapiens OX=9606 GN=SF3B2 PE=1 SV=2 5.32 2622.8 - 1.04E+06 - - - -1.0864 - 2.293 0.41 - 161.5 1 2 0 -0.0015 12 0 0 0 1.63E+07 1.26E+07 - - - 5.4109 0.9983 221125_WJC_METTL3_EV_vs_WT_F03.13582.13582.2 0.00352 14-Aug R.TVITEEFK.V sp|Q96I24|FUBP3_HUMAN 1 965.507 0.96 29526 13582 2 965.504884 483.7608 Far upstream element-binding protein 3 OS=Homo sapiens OX=9606 GN=FUBP3 PE=1 SV=2 4.53 2623.3 - 2.94E+06 - - - -2.1533 - 1.519 0.321 - 186.9 1 2 0 -0.0021 8 0 0 0 8.70E+07 9.05E+07 - - - 2.6721 0.9997 221125_WJC_METTL3_EV_vs_WT_F03.13583.13583.2 0.00184 16-Oct R.IDGITIQAR.Q "sp|Q13813|SPTN1_HUMAN,tr|A0A0D9SF54|A0A0D9SF54_HUMAN,tr|A0A0D9SGF6|A0A0D9SGF6_HUMAN" 3 985.5556 1.77 29527 13583 2 985.555779 493.7851 "Spectrin alpha chain, non-erythrocytic 1 OS=Homo sapiens OX=9606 GN=SPTAN1 PE=1 SV=3" 5.84 2623.4 - 2.55E+06 - - - 0.137 - 1.928 0.366 - 292.2 1 2 0 0.0001 9 0 0 0 4.43E+07 2.50E+07 - - - 3.6435 0.9606 221125_WJC_METTL3_EV_vs_WT_F03.13584.13584.2 0.734 12-Jul R.FAGVDIR.V "sp|P62249|RS16_HUMAN,tr|M0R210|M0R210_HUMAN,tr|M0R3H0|M0R3H0_HUMAN,tr|M0QX76|M0QX76_HUMAN,tr|M0R1M5|M0R1M5_HUMAN,tr|Q6IPX4|Q6IPX4_HUMAN" 6 776.4181 1.8 29528 13584 2 776.418207 389.2163 40S ribosomal protein S16 OS=Homo sapiens OX=9606 GN=RPS16 PE=1 SV=2 5.84 2623.5 - 1.37E+06 - - - 0.1533 - 1.128 0.041 - 125.5 1 2 0 0.0001 7 0 0 0 3.86E+07 2.14E+07 - - - -0.2746 0.9991 221125_WJC_METTL3_EV_vs_WT_F03.13585.13585.2 0.0259 14-Aug K.DLEEWNQR[166.11].Q sp|P09497|CLCB_HUMAN 1 1098.497 0.54 29529 13585 2 1098.494234 550.2558 Clathrin light chain B OS=Homo sapiens OX=9606 GN=CLTB PE=1 SV=1 4.14 2623.6 - 1.13E+06 - - - -2.4788 - 1.707 0.398 - 246.5 1 2 0 -0.0027 8 0 0 0 1.11E+07 2.06E+07 - - - 3.5925 0.9974 221125_WJC_METTL3_EV_vs_WT_F03.13586.13586.2 0.0364 24-Sep R.GPLPAAPPVAPER.Q "sp|Q9NQC3|RTN4_HUMAN,tr|F8W914|F8W914_HUMAN" 2 1270.7034 1.21 29530 13586 2 1270.701464 636.359 Reticulon-4 OS=Homo sapiens OX=9606 GN=RTN4 PE=1 SV=2 6 2623.7 - 759749 - - - -1.5007 - 1.371 0.284 - 185.6 1 2 0 -0.0019 13 0 0 0 3.76E+07 3.10E+07 - - - 1.9479 0.9998 221125_WJC_METTL3_EV_vs_WT_F03.13590.13590.2 0.000227 18-Sep K.STLTDSLVC[160.03]K[136.11].A sp|P13639|EF2_HUMAN 1 1130.5733 0.46 29533 13590 2 1130.574738 566.2939 Elongation factor 2 OS=Homo sapiens OX=9606 GN=EEF2 PE=1 SV=4 5.55 2624.1 - 5.92E+06 - - - 1.294 - 2.201 0.433 - 306.3 1 2 0 0.0015 10 0 0 0 2.36E+08 5.12E+08 - - - 4.4408 0.9999 221125_WJC_METTL3_EV_vs_WT_F03.13593.13593.2 0.00445 18-Dec K.C[160.03]PFTGNVSIR.G "sp|P62280|RS11_HUMAN,tr|M0QZC5|M0QZC5_HUMAN" 2 1149.5601 0.9 29535 13593 2 1149.559989 575.7873 40S ribosomal protein S11 OS=Homo sapiens OX=9606 GN=RPS11 PE=1 SV=3 8.25 2624.4 - 1.34E+07 - - - -0.0774 - 2.301 0.509 - 730.1 1 2 0 -0.0001 10 0 0 0 1.25E+09 1.38E+09 - - - 5.1266 0.9997 221125_WJC_METTL3_EV_vs_WT_F03.13596.13596.2 0.000277 20-Aug R.DVPAYSQDTFK.V "sp|P04843|RPN1_HUMAN,tr|B7Z4L4|B7Z4L4_HUMAN" 2 1269.5877 1.27 29538 13596 2 1269.589072 635.8011 Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit 1 OS=Homo sapiens OX=9606 GN=RPN1 PE=1 SV=1 4.21 2624.6 - 1.33E+06 - - - 1.0547 - 1.711 0.443 - 199.4 1 2 0 0.0013 11 0 0 0 1.08E+08 8.50E+07 - - - 3.7655 0.9321 221125_WJC_METTL3_EV_vs_WT_F03.13597.13597.3 1.78 Jun-36 R.FLPSPVVIK[136.11]K[136.11].R "sp|Q13618|CUL3_HUMAN,tr|H7C399|H7C399_HUMAN,tr|A0A087WTG3|A0A087WTG3_HUMAN" 3 1142.7398 0.001 29539 13597 3 1142.739232 381.9205 Cullin-3 OS=Homo sapiens OX=9606 GN=CUL3 PE=1 SV=2 10 2624.7 - 285858 - - - -0.5119 - 1.176 0.194 - 27.9 12 2 0 -0.0006 10 0 0 0 0.00E+00 5.88E+06 - - - 0.6767 0.9992 221125_WJC_METTL3_EV_vs_WT_F03.13599.13599.2 0.00448 18-Oct K.QSLPPGLAVK.E sp|P63173|RL38_HUMAN 1 1008.5968 1.16 29540 13599 2 1008.597281 505.3057 60S ribosomal protein L38 OS=Homo sapiens OX=9606 GN=RPL38 PE=1 SV=2 8.75 2624.9 - 5.09E+07 - - - 0.4957 - 1.652 0.299 - 382.1 1 2 0 0.0005 10 0 0 0 2.38E+09 2.05E+09 - - - 2.6505 0.9999 221125_WJC_METTL3_EV_vs_WT_F03.13601.13601.2 7.56E-08 14/24 K.AGNLGGGVVTIER[166.11].S "sp|P35268|RL22_HUMAN,tr|K7EKS7|K7EKS7_HUMAN,tr|K7ERI7|K7ERI7_HUMAN,tr|K7EMH1|K7EMH1_HUMAN,tr|K7ELC4|K7ELC4_HUMAN,tr|K7EP65|K7EP65_HUMAN,tr|K7EJT5|K7EJT5_HUMAN" 7 1251.6811 0.93 29541 13601 2 1251.680651 626.8478 60S ribosomal protein L22 OS=Homo sapiens OX=9606 GN=RPL22 PE=1 SV=2 6.05 2625.1 - 1.96E+07 - - - -0.3347 - 2.624 0.543 - 640.2 1 2 0 -0.0004 13 0 0 0 2.26E+09 2.42E+09 - - - 5.5274 0.9998 221125_WJC_METTL3_EV_vs_WT_F03.13602.13602.2 0.00167 16/24 K.ALIAAQYSGAQVR[166.11].V sp|P26641|EF1G_HUMAN 1 1356.7389 1.13 29542 13602 2 1356.738094 679.3767 Elongation factor 1-gamma OS=Homo sapiens OX=9606 GN=EEF1G PE=1 SV=3 8.79 2625.2 - 3.18E+06 - - - -0.6081 - 2.812 0.363 - 1115.8 1 2 0 -0.0008 13 0 0 0 3.17E+08 2.82E+08 - - - 4.3754 0.9995 221125_WJC_METTL3_EV_vs_WT_F03.13606.13606.2 0.00271 20-Nov K.VVLIGDSGVGK.S "sp|Q15907|RB11B_HUMAN,sp|P62491|RB11A_HUMAN,tr|B4DQU5|B4DQU5_HUMAN,tr|H3BMH2|H3BMH2_HUMAN,tr|H3BSC1|H3BSC1_HUMAN" 5 1042.6023 1.09 29546 13606 2 1042.604374 522.3084 Ras-related protein Rab-11B OS=Homo sapiens OX=9606 GN=RAB11B PE=1 SV=4 5.81 2625.6 - 754472 - - - 2.0276 - 2.107 0.413 - 402.2 1 2 0 0.0021 11 0 0 0 4.44E+07 4.06E+07 - - - 4.1069 1 221125_WJC_METTL3_EV_vs_WT_F03.13611.13611.2 1.40E-07 13/20 R.TLSGMESYC[160.03]VR[166.11].A sp|P50991|TCPD_HUMAN 1 1311.5827 0.24 29549 13611 2 1311.580286 656.7986 T-complex protein 1 subunit delta OS=Homo sapiens OX=9606 GN=CCT4 PE=1 SV=4 5.66 2626.2 - 7.25E+06 - - - -1.8238 - 2.303 0.69 - 445.5 1 2 0 -0.0024 11 0 0 0 1.26E+08 5.32E+08 - - - 6.3933 0.9998 221125_WJC_METTL3_EV_vs_WT_F03.13612.13612.2 0.000311 18-Sep K.STLTDSLVC[160.03]K.A sp|P13639|EF2_HUMAN 1 1122.5591 0.46 29550 13612 2 1122.560312 562.2868 Elongation factor 2 OS=Homo sapiens OX=9606 GN=EEF2 PE=1 SV=4 5.55 2626.2 - 7.46E+06 - - - 1.1019 - 2.11 0.454 - 304.5 1 2 0 0.0012 10 0 0 0 2.37E+08 5.16E+08 - - - 4.4781 0.9984 221125_WJC_METTL3_EV_vs_WT_F03.13613.13613.2 0.0258 14-Aug R.NILFTGNK[136.11].K "sp|Q6ULP2|AFTIN_HUMAN,tr|B8ZZI9|B8ZZI9_HUMAN" 2 913.5113 1.92 29551 13613 2 913.509823 457.7629 Aftiphilin OS=Homo sapiens OX=9606 GN=AFTPH PE=1 SV=3 8.75 2626.4 - 1.14E+06 - - - -1.5807 - 1.516 0.282 - 162.1 1 2 0 -0.0014 8 0 0 0 3.78E+07 1.97E+07 - - - 2.3783 0.9149 221125_WJC_METTL3_EV_vs_WT_F03.13615.13615.2 0.307 18-Aug K.IPVGPETLGR.L "sp|P06576|ATPB_HUMAN,tr|F8W079|F8W079_HUMAN,tr|H0YH81|H0YH81_HUMAN" 3 1037.5869 75.12 29553 13615 2 1037.581879 519.8007 "ATP synthase subunit beta, mitochondrial OS=Homo sapiens OX=9606 GN=ATP5F1B PE=1 SV=3" 6 2626.6 - 827428 - - - -4.8825 - 1.306 0.174 - 110.2 1 2 0 -0.0051 10 0 0 0 3.48E+07 4.63E+05 - - - 1.0698 0.9833 221125_WJC_METTL3_EV_vs_WT_F03.13616.13616.2 0.0631 14-Aug R.QINLSNIR.A sp|Q7KZF4|SND1_HUMAN 1 956.5403 0.84 29554 13616 2 956.538047 479.2774 Staphylococcal nuclease domain-containing protein 1 OS=Homo sapiens OX=9606 GN=SND1 PE=1 SV=1 9.75 2626.8 - 574416 - - - -2.3857 - 1.468 0.106 - 256.3 1 2 0 -0.0023 8 0 0 0 3.62E+07 4.30E+07 - - - 0.981 0.9996 221125_WJC_METTL3_EV_vs_WT_F03.13617.13617.2 2.10E-05 24-Sep K.GQNVLLTENAEVK[136.11].L "sp|Q9UKE5|TNIK_HUMAN,sp|O95819|M4K4_HUMAN,sp|Q8N4C8|MINK1_HUMAN,tr|I3L2I2|I3L2I2_HUMAN,tr|A0A0D9SEY1|A0A0D9SEY1_HUMAN,tr|C9J840|C9J840_HUMAN,tr|E7EX83|E7EX83_HUMAN,tr|A0A590UJE1|A0A590UJE1_HUMAN,tr|C9J338|C9J338_HUMAN,tr|E7EN19|E7EN19_HUMAN,tr|H7C360|H7C360_HUMAN,tr|A0A0D9SG62|A0A0D9SG62_HUMAN,tr|G3XAA2|G3XAA2_HUMAN,tr|E7ENQ1|E7ENQ1_HUMAN,tr|G5E948|G5E948_HUMAN" 15 1421.7606 0.45 29555 13617 2 1421.75787 711.8876 TRAF2 and NCK-interacting protein kinase OS=Homo sapiens OX=9606 GN=TNIK PE=1 SV=1 4.53 2626.9 - 352959 - - - -1.8906 - 2.113 0.444 - 255.7 1 2 0 -0.0027 13 0 0 0 2.13E+06 4.72E+06 - - - 4.2396 0.9987 221125_WJC_METTL3_EV_vs_WT_F03.13620.13620.2 0.211 18-Sep K.QSLPPGLAVK[136.11].E sp|P63173|RL38_HUMAN 1 1016.611 1.16 29557 13620 2 1016.61028 509.3128 60S ribosomal protein L38 OS=Homo sapiens OX=9606 GN=RPL38 PE=1 SV=2 8.75 2627.2 - 4.50E+07 - - - -0.6895 - 1.745 0.221 - 307.1 1 2 0 -0.0007 10 0 0 0 2.38E+09 2.05E+09 - - - 2.2272 0.979 221125_WJC_METTL3_EV_vs_WT_F03.13622.13622.2 4.03 12-Jul R.SIFDHIK.L "sp|Q9NYF8|BCLF1_HUMAN,tr|E9PKI6|E9PKI6_HUMAN,tr|A0A1W2PQ43|A0A1W2PQ43_HUMAN,tr|E9PK91|E9PK91_HUMAN,tr|E9PJA7|E9PJA7_HUMAN,tr|E9PK09|E9PK09_HUMAN,tr|E9PQN2|E9PQN2_HUMAN" 7 858.46 2.07 29558 13622 2 858.459312 430.2373 Bcl-2-associated transcription factor 1 OS=Homo sapiens OX=9606 GN=BCLAF1 PE=1 SV=2 6.46 2627.4 - 7.15E+06 - - - -0.7467 - 1.022 0.145 - 127.3 1 2 0 -0.0006 7 0 0 0 4.37E+09 2.12E+09 - - - 0.1807 0.9998 221125_WJC_METTL3_EV_vs_WT_F03.13623.13623.2 2.23E-05 20-Sep R.DVPAYSQDTFK[136.11].V "sp|P04843|RPN1_HUMAN,tr|B7Z4L4|B7Z4L4_HUMAN" 2 1277.6019 1.28 29559 13623 2 1277.600152 639.8082 Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit 1 OS=Homo sapiens OX=9606 GN=RPN1 PE=1 SV=1 4.21 2627.5 - 2.93E+06 - - - -1.394 - 1.836 0.504 - 231.1 1 2 0 -0.0018 11 0 0 0 1.09E+08 8.50E+07 - - - 4.4067 0.9871 221125_WJC_METTL3_EV_vs_WT_F03.13625.13625.2 0.00152 16-Sep R.SGYLLPDTK[136.11].A "sp|P14625|ENPL_HUMAN,tr|A0A7P0T917|A0A7P0T917_HUMAN,tr|A0A7P0T823|A0A7P0T823_HUMAN,tr|A0A7P0TAE1|A0A7P0TAE1_HUMAN,tr|H0YIV0|H0YIV0_HUMAN,tr|A0A7P0TAT8|A0A7P0TAT8_HUMAN" 6 1000.5321 1.01 29561 13625 2 1000.526334 501.2733 Endoplasmin OS=Homo sapiens OX=9606 GN=HSP90B1 PE=1 SV=1 5.55 2627.6 - 2.09E+06 - - - -5.725 - 1.724 0.355 - 241.3 1 2 0 -0.0057 9 0 0 0 7.84E+07 7.75E+07 - - - 3.2369 0.9716 221125_WJC_METTL3_EV_vs_WT_F03.13626.13626.2 0.00351 16-Aug K.FFTEEVDSR[166.11].K "sp|Q9H845|ACAD9_HUMAN,tr|A0A7P0Z450|A0A7P0Z450_HUMAN,tr|A0A7P0TB68|A0A7P0TB68_HUMAN,tr|A0A7P0T871|A0A7P0T871_HUMAN,tr|A0A7P0T7Z1|A0A7P0T7Z1_HUMAN,tr|A0A7P0T9N9|A0A7P0T9N9_HUMAN,tr|A0A7P0T8U3|A0A7P0T8U3_HUMAN,tr|A0A7P0TB58|A0A7P0TB58_HUMAN" 8 1138.517 0.75 29562 13626 2 1138.509662 570.2658 "Complex I assembly factor ACAD9, mitochondrial OS=Homo sapiens OX=9606 GN=ACAD9 PE=1 SV=1" 4.14 2627.7 - 1.60E+06 - - - -6.4663 - 1.456 0.38 - 188.4 1 2 0 -0.0074 9 0 0 0 2.52E+07 3.35E+07 - - - 2.9323 0.9723 221125_WJC_METTL3_EV_vs_WT_F03.13627.13627.3 0.728 Sep-32 K.FFLSHPAYR[166.11].H "sp|Q9UQ16|DYN3_HUMAN,sp|P50570|DYN2_HUMAN,tr|E5RIK2|E5RIK2_HUMAN,tr|K7EMQ3|K7EMQ3_HUMAN,tr|E5RHK8|E5RHK8_HUMAN" 5 1146.585 0.001 29563 13627 3 1146.582934 383.2023 Dynamin-3 OS=Homo sapiens OX=9606 GN=DNM3 PE=1 SV=4 8.75 2627.8 - 412066 - - - -1.7879 - 1.631 0.142 - 60.6 2 2 0 -0.0021 9 0 0 0 0.00E+00 9.66E+06 - - - 1.4576 0.9899 221125_WJC_METTL3_EV_vs_WT_F03.13631.13631.2 0.0334 12-Jun R.SIFDHIK[136.11].L "sp|Q9NYF8|BCLF1_HUMAN,tr|E9PKI6|E9PKI6_HUMAN,tr|A0A1W2PQ43|A0A1W2PQ43_HUMAN,tr|E9PK91|E9PK91_HUMAN,tr|E9PJA7|E9PJA7_HUMAN,tr|E9PK09|E9PK09_HUMAN,tr|E9PQN2|E9PQN2_HUMAN" 7 866.4742 2.07 29565 13631 2 866.47307 434.2444 Bcl-2-associated transcription factor 1 OS=Homo sapiens OX=9606 GN=BCLAF1 PE=1 SV=2 6.46 2628.3 - 1.09E+07 - - - -1.2499 - 1.161 0.176 - 88.1 1 2 0 -0.0011 7 0 0 0 4.37E+09 2.12E+09 - - - 0.8136 0.9998 221125_WJC_METTL3_EV_vs_WT_F03.13632.13632.2 0.000234 24-Dec K.AGGVGLNLSAASR.V "sp|Q14527|HLTF_HUMAN,tr|H7C5K0|H7C5K0_HUMAN,tr|A0A0C4DGA6|A0A0C4DGA6_HUMAN" 3 1171.6309 1.22 29566 13632 2 1171.630139 586.8227 Helicase-like transcription factor OS=Homo sapiens OX=9606 GN=HLTF PE=1 SV=2 9.79 2628.4 - 2.96E+06 - - - -0.6794 - 2.148 0.459 - 500.2 1 2 0 -0.0008 13 0 0 0 7.20E+07 5.92E+07 - - - 4.3931 0.9989 221125_WJC_METTL3_EV_vs_WT_F03.13634.13634.2 0.00281 16-Aug R.SGYLLPDTK.A "sp|P14625|ENPL_HUMAN,tr|A0A7P0T917|A0A7P0T917_HUMAN,tr|A0A7P0T823|A0A7P0T823_HUMAN,tr|A0A7P0TAE1|A0A7P0TAE1_HUMAN,tr|H0YIV0|H0YIV0_HUMAN,tr|A0A7P0TAT8|A0A7P0TAT8_HUMAN" 6 992.5179 1.01 29568 13634 2 992.516922 497.2662 Endoplasmin OS=Homo sapiens OX=9606 GN=HSP90B1 PE=1 SV=1 5.55 2628.5 - 2.84E+06 - - - -0.9471 - 1.347 0.338 - 133.6 1 2 0 -0.0009 9 0 0 0 7.84E+07 7.75E+07 - - - 2.399 0.9993 221125_WJC_METTL3_EV_vs_WT_F03.13635.13635.3 0.0109 Sep-48 K.AGNLGGGVVTIER[166.11].S "sp|P35268|RL22_HUMAN,tr|K7EKS7|K7EKS7_HUMAN,tr|K7ERI7|K7ERI7_HUMAN,tr|K7EMH1|K7EMH1_HUMAN,tr|K7ELC4|K7ELC4_HUMAN,tr|K7EP65|K7EP65_HUMAN,tr|K7EJT5|K7EJT5_HUMAN" 7 1251.6811 1.75 29569 13635 3 1251.67899 418.2343 60S ribosomal protein L22 OS=Homo sapiens OX=9606 GN=RPL22 PE=1 SV=2 6.05 2628.5 - 1.83E+06 - - - -1.6618 - 1.95 0.309 - 135.3 1 2 0 -0.0021 13 0 0 0 1.04E+08 5.96E+07 - - - 3.7951 0.9999 221125_WJC_METTL3_EV_vs_WT_F03.13636.13636.2 2.47E-05 20-Nov K.AENSSLNLIGK.A "sp|P46459|NSF_HUMAN,tr|I3L0N3|I3L0N3_HUMAN" 2 1144.6088 0.85 29570 13636 2 1144.609203 573.3117 Vesicle-fusing ATPase OS=Homo sapiens OX=9606 GN=NSF PE=1 SV=3 6.05 2628.6 - 1.71E+06 - - - 0.3503 - 2.343 0.479 - 428 1 2 0 0.0004 11 0 0 0 2.92E+07 3.42E+07 - - - 4.8821 0.9996 221125_WJC_METTL3_EV_vs_WT_F03.13637.13637.2 0.0743 13/22 R.MDSTNADALYVR[166.11].G "sp|Q99615|DNJC7_HUMAN,tr|A0A6I8PRZ0|A0A6I8PRZ0_HUMAN,tr|A0A6I8PLE7|A0A6I8PLE7_HUMAN,tr|A0A6I8PR89|A0A6I8PR89_HUMAN,tr|A0A6I8PIK4|A0A6I8PIK4_HUMAN,tr|A0A6I8PUC2|A0A6I8PUC2_HUMAN,tr|A0A6I8PS32|A0A6I8PS32_HUMAN,tr|K7EPP7|K7EPP7_HUMAN,tr|A0A6I8PUD4|A0A6I8PUD4_HUMAN,tr|K7EIH8|K7EIH8_HUMAN,tr|K7ER44|K7ER44_HUMAN,tr|A0A6I8PU73|A0A6I8PU73_HUMAN,tr|K7EK03|K7EK03_HUMAN,tr|A0A6I8PU89|A0A6I8PU89_HUMAN" 14 1364.627 0.51 29571 13637 2 1364.622922 683.3208 DnaJ homolog subfamily C member 7 OS=Homo sapiens OX=9606 GN=DNAJC7 PE=1 SV=2 4.21 2628.8 - 1.66E+06 - - - -2.9774 - 2.911 0.468 - 694.6 1 2 0 -0.0041 12 0 0 0 1.85E+07 3.66E+07 - - - 5.3078 0.9516 221125_WJC_METTL3_EV_vs_WT_F03.13641.13641.2 0.0295 20-Sep R.LESTLNYGMER[166.11].V "sp|P35606|COPB2_HUMAN,tr|H0Y938|H0Y938_HUMAN,tr|A0A7I2V258|A0A7I2V258_HUMAN,tr|H0YAC7|H0YAC7_HUMAN" 4 1321.6212 0.001 29574 13641 2 1321.611582 661.8179 Coatomer subunit beta' OS=Homo sapiens OX=9606 GN=COPB2 PE=1 SV=2 4.53 2629.3 - 526601 - - - -7.2555 - 1.682 0.331 - 200.4 1 2 0 -0.0096 11 0 0 0 0.00E+00 1.19E+07 - - - 2.8894 1 221125_WJC_METTL3_EV_vs_WT_F03.13643.13643.2 1.96E-07 13/20 R.TLSGMESYC[160.03]VR.A sp|P50991|TCPD_HUMAN 1 1301.5744 0.24 29575 13643 2 1301.572574 651.7945 T-complex protein 1 subunit delta OS=Homo sapiens OX=9606 GN=CCT4 PE=1 SV=4 5.66 2629.5 - 6.34E+06 - - - -1.4091 - 2.288 0.671 - 476 1 2 0 -0.0018 11 0 0 0 1.26E+08 5.32E+08 - - - 6.2355 0.9999 221125_WJC_METTL3_EV_vs_WT_F03.13646.13646.3 0.122 15/48 K.ALIAAQYSGAQVR.V sp|P26641|EF1G_HUMAN 1 1346.7306 0.87 29578 13646 3 1346.729204 449.9175 Elongation factor 1-gamma OS=Homo sapiens OX=9606 GN=EEF1G PE=1 SV=3 8.79 2629.6 - 2.75E+06 - - - -1.073 - 2.948 0.374 - 378.7 1 2 0 -0.0014 13 0 0 0 5.26E+07 6.05E+07 - - - 5.6406 0.9996 221125_WJC_METTL3_EV_vs_WT_F03.13647.13647.2 0.0274 14-Oct R.DIDNLVQR[166.11].N sp|P49257|LMAN1_HUMAN 1 981.5119 1.16 29579 13647 2 981.513139 491.7632 Protein ERGIC-53 OS=Homo sapiens OX=9606 GN=LMAN1 PE=1 SV=2 4.21 2629.7 - 2.50E+06 - - - 1.2837 - 1.86 0.368 - 329.4 1 2 0 0.0013 8 0 0 0 5.77E+07 4.97E+07 - - - 3.6303 0.9997 221125_WJC_METTL3_EV_vs_WT_F03.13652.13652.3 6.03E-05 13/44 K.AITAGYFYHTAR.L "sp|O60231|DHX16_HUMAN,tr|Q5SQH5|Q5SQH5_HUMAN,tr|A0A140T8Y5|A0A140T8Y5_HUMAN" 3 1369.6779 1.5 29582 13652 3 1369.672151 457.5666 Pre-mRNA-splicing factor ATP-dependent RNA helicase DHX16 OS=Homo sapiens OX=9606 GN=DHX16 PE=1 SV=2 8.64 2630.4 - 998576 - - - -4.1864 - 2.676 0.476 - 228.3 1 2 0 -0.0057 12 0 0 0 2.07E+07 1.38E+07 - - - 6.5737 0.9999 221125_WJC_METTL3_EV_vs_WT_F03.13653.13653.2 9.60E-05 22-Dec R.TIEYLQPNPASR[166.11].A "sp|Q99961|SH3G1_HUMAN,sp|Q99962|SH3G2_HUMAN,tr|M0R0I3|M0R0I3_HUMAN,tr|M0QYE0|M0QYE0_HUMAN" 4 1397.7178 1.87 29583 13653 2 1397.716532 699.8662 Endophilin-A2 OS=Homo sapiens OX=9606 GN=SH3GL1 PE=1 SV=1 5.66 2630.5 - 575488 - - - -0.9423 - 2.804 0.421 - 522.5 1 2 0 -0.0013 12 0 0 0 8.32E+07 4.45E+07 - - - 4.863 0.9982 221125_WJC_METTL3_EV_vs_WT_F03.13654.13654.2 0.00679 22-Dec K.GLSPAMSPALQR.L sp|Q96DF8|ESS2_HUMAN 1 1226.6441 1.79 29584 13654 2 1226.649398 614.3293 Splicing factor ESS-2 homolog OS=Homo sapiens OX=9606 GN=ESS2 PE=1 SV=1 9.75 2630.6 - 2.35E+06 - - - 4.2849 - 2.335 0.436 - 715.9 1 2 0 0.0053 12 0 0 0 4.67E+07 2.62E+07 - - - 4.4909 0.9947 221125_WJC_METTL3_EV_vs_WT_F03.13656.13656.2 0.485 12-May K.AWEEYYK.K "sp|Q92945|FUBP2_HUMAN,sp|Q92945|FUBP2_HUMAN,sp|Q96AE4|FUBP1_HUMAN,tr|E9PEB5|E9PEB5_HUMAN,tr|M0R263|M0R263_HUMAN,tr|M0R3J3|M0R3J3_HUMAN,tr|M0R0C6|M0R0C6_HUMAN,tr|M0R0C6|M0R0C6_HUMAN,tr|M0QYG1|M0QYG1_HUMAN,tr|A0A087WTP3|A0A087WTP3_HUMAN,tr|M0R251|M0R251_HUMAN" 11 987.4338 1.02 29586 13656 2 987.432749 494.7242 Far upstream element-binding protein 2 OS=Homo sapiens OX=9606 GN=KHSRP PE=1 SV=4 4.53 2630.9 - 1.12E+06 - - - -1.0623 - 1.046 0.275 - 93.3 1 2 0 -0.001 7 0 0 0 1.75E+07 1.72E+07 - - - 1.2143 0.9964 221125_WJC_METTL3_EV_vs_WT_F03.13661.13661.2 0.186 20-Oct K.GALTLSSPEVR[166.11].F "sp|Q9Y2L1|RRP44_HUMAN,tr|G3V1J5|G3V1J5_HUMAN" 2 1138.6222 1.82 29589 13661 2 1138.624613 570.3184 Exosome complex exonuclease RRP44 OS=Homo sapiens OX=9606 GN=DIS3 PE=1 SV=2 6 2631.5 - 2.16E+06 - - - 2.1561 - 1.658 0.225 - 263.5 1 2 0 0.0025 11 0 0 0 4.94E+08 2.72E+08 - - - 2.0699 0.9999 221125_WJC_METTL3_EV_vs_WT_F03.13662.13662.3 0.00165 17/40 R.LLASTLVHSVK[136.11].K "sp|Q9NYF8|BCLF1_HUMAN,tr|E9PKI6|E9PKI6_HUMAN,tr|A0A1W2PQ43|A0A1W2PQ43_HUMAN,tr|E9PK91|E9PK91_HUMAN,tr|E9PJA7|E9PJA7_HUMAN,tr|E9PK09|E9PK09_HUMAN,tr|E9PQN2|E9PQN2_HUMAN" 7 1174.7165 2.05 29590 13662 3 1174.71555 392.5794 Bcl-2-associated transcription factor 1 OS=Homo sapiens OX=9606 GN=BCLAF1 PE=1 SV=2 8.76 2631.6 - 1.74E+06 - - - -0.8164 - 2.609 0.41 - 247.2 1 2 0 -0.001 11 0 0 0 1.58E+10 7.73E+09 - - - 5.8351 0.9996 221125_WJC_METTL3_EV_vs_WT_F03.13663.13663.2 2.34E-05 20-Nov K.VVLIGDSGVGK[136.11].S "sp|Q15907|RB11B_HUMAN,sp|P62491|RB11A_HUMAN,tr|B4DQU5|B4DQU5_HUMAN,tr|H3BMH2|H3BMH2_HUMAN,tr|H3BSC1|H3BSC1_HUMAN" 5 1050.6165 1.17 29591 13663 2 1050.613681 526.3155 Ras-related protein Rab-11B OS=Homo sapiens OX=9606 GN=RAB11B PE=1 SV=4 5.81 2631.6 - 2.74E+06 - - - -2.6451 - 2.045 0.52 - 407.5 1 2 0 -0.0028 11 0 0 0 4.85E+07 4.13E+07 - - - 4.8162 0.9997 221125_WJC_METTL3_EV_vs_WT_F03.13671.13671.3 0.000792 18/44 K.AITAGYFYHTAR[166.11].L "sp|O60231|DHX16_HUMAN,tr|Q5SQH5|Q5SQH5_HUMAN,tr|A0A140T8Y5|A0A140T8Y5_HUMAN" 3 1379.6862 1.48 29597 13671 3 1379.681386 460.9027 Pre-mRNA-splicing factor ATP-dependent RNA helicase DHX16 OS=Homo sapiens OX=9606 GN=DHX16 PE=1 SV=2 8.64 2632.6 - 1.21E+06 - - - -3.4566 - 2.65 0.397 - 402.3 1 2 0 -0.0048 12 0 0 0 2.07E+07 1.40E+07 - - - 5.6662 0.9998 221125_WJC_METTL3_EV_vs_WT_F03.13672.13672.2 0.0101 24-Dec K.IIDDSDSNLSVVK[136.11].K "sp|P0DJD0|RGPD1_HUMAN,sp|Q7Z3J3|RGPD4_HUMAN,sp|P49792|RBP2_HUMAN,sp|P0DJD1|RGPD2_HUMAN,sp|A6NKT7|RGPD3_HUMAN,tr|A0A286YES2|A0A286YES2_HUMAN,tr|F8VYC4|F8VYC4_HUMAN,tr|J3KNE0|J3KNE0_HUMAN,tr|A0A1W2PNU4|A0A1W2PNU4_HUMAN" 9 1411.7286 1.01 29598 13672 2 1411.730858 706.8716 RANBP2-like and GRIP domain-containing protein 1 OS=Homo sapiens OX=9606 GN=RGPD1 PE=2 SV=1 3.93 2632.8 - 682817 - - - 1.6065 - 2.235 0.486 - 285.6 1 2 0 0.0023 13 0 0 0 3.44E+07 3.41E+07 - - - 4.694 0.998 221125_WJC_METTL3_EV_vs_WT_F03.13674.13674.2 0.0126 18-Oct R.TFATALDTTR.H sp|Q9BT25|HAUS8_HUMAN 1 1095.556 1.56 29600 13674 2 1095.552346 548.7853 HAUS augmin-like complex subunit 8 OS=Homo sapiens OX=9606 GN=HAUS8 PE=1 SV=3 5.5 2633 - 850150 - - - -3.37 - 1.882 0.357 - 301.1 1 2 0 -0.0037 10 0 0 0 3.37E+07 2.17E+07 - - - 3.4417 0.9998 221125_WJC_METTL3_EV_vs_WT_F03.13677.13677.2 4.20E-06 22-Nov K.AFEEDIETPPTR.N sp|Q9P2D1|CHD7_HUMAN 1 1403.6569 1.37 29603 13677 2 1403.65441 702.8357 Chromodomain-helicase-DNA-binding protein 7 OS=Homo sapiens OX=9606 GN=CHD7 PE=1 SV=3 4 2633.4 - 608083 - - - -1.7561 - 2.269 0.574 - 360.2 1 2 0 -0.0025 12 0 0 0 3.39E+07 2.47E+07 - - - 5.4356 0.9999 221125_WJC_METTL3_EV_vs_WT_F03.13681.13681.2 3.90E-06 22-Oct K.ILIANTGMDTDK[136.11].L "sp|P78371|TCPB_HUMAN,tr|F8VQ14|F8VQ14_HUMAN,tr|F5GWF6|F5GWF6_HUMAN" 3 1298.6632 0.51 29605 13681 2 1298.662344 650.3389 T-complex protein 1 subunit beta OS=Homo sapiens OX=9606 GN=CCT2 PE=1 SV=4 4.21 2633.8 - 1.23E+07 - - - -0.6229 - 2.403 0.553 - 269.2 1 2 0 -0.0008 12 0 0 0 3.88E+08 7.58E+08 - - - 5.432 0.9991 221125_WJC_METTL3_EV_vs_WT_F03.13682.13682.2 0.0854 20-Nov R.LLASTLVHSVK.K "sp|Q9NYF8|BCLF1_HUMAN,tr|E9PKI6|E9PKI6_HUMAN,tr|A0A1W2PQ43|A0A1W2PQ43_HUMAN,tr|E9PK91|E9PK91_HUMAN,tr|E9PJA7|E9PJA7_HUMAN,tr|E9PK09|E9PK09_HUMAN,tr|E9PQN2|E9PQN2_HUMAN" 7 1166.7023 2.07 29606 13682 2 1166.700933 584.3584 Bcl-2-associated transcription factor 1 OS=Homo sapiens OX=9606 GN=BCLAF1 PE=1 SV=2 8.76 2633.9 - 8.46E+06 - - - -1.1794 - 2.116 0.219 - 322.6 1 2 0 -0.0014 11 0 0 0 5.78E+09 2.80E+09 - - - 2.6858 0.9998 221125_WJC_METTL3_EV_vs_WT_F03.13683.13683.2 0.00076 20-Dec R.LLASTLVHSVK[136.11].K "sp|Q9NYF8|BCLF1_HUMAN,tr|E9PKI6|E9PKI6_HUMAN,tr|A0A1W2PQ43|A0A1W2PQ43_HUMAN,tr|E9PK91|E9PK91_HUMAN,tr|E9PJA7|E9PJA7_HUMAN,tr|E9PK09|E9PK09_HUMAN,tr|E9PQN2|E9PQN2_HUMAN" 7 1174.7165 2.07 29607 13683 2 1174.714834 588.3655 Bcl-2-associated transcription factor 1 OS=Homo sapiens OX=9606 GN=BCLAF1 PE=1 SV=2 8.76 2633.9 - 5.58E+06 - - - -1.4259 - 2.414 0.418 - 450.1 1 2 0 -0.0017 11 0 0 0 5.78E+09 2.80E+09 - - - 4.5119 0.9993 221125_WJC_METTL3_EV_vs_WT_F03.13684.13684.2 0.152 16-Aug K.IDPSALVQK[136.11].L "sp|Q9NSI2|SLX9_HUMAN,tr|C9JJU7|C9JJU7_HUMAN" 2 977.5637 1.68 29608 13684 2 977.562586 489.7891 Ribosome biogenesis protein SLX9 homolog OS=Homo sapiens OX=9606 GN=SLX9 PE=1 SV=2 5.84 2634 - 4.10E+06 - - - -1.1355 - 1.807 0.297 - 181 1 2 0 -0.0011 9 0 0 0 8.37E+08 4.98E+08 - - - 2.946 0.9999 221125_WJC_METTL3_EV_vs_WT_F03.13686.13686.2 0.000101 18-Nov R.FESSGQDMFR.E "sp|Q15643|TRIPB_HUMAN,tr|H0YJ97|H0YJ97_HUMAN" 2 1202.5026 1.08 29610 13686 2 1202.502145 602.2586 Thyroid receptor-interacting protein 11 OS=Homo sapiens OX=9606 GN=TRIP11 PE=1 SV=3 4.37 2634.1 - 2.82E+06 - - - -0.3975 - 1.988 0.552 - 342.3 1 2 0 -0.0005 10 0 0 0 1.12E+08 1.04E+08 - - - 5.0359 0.9998 221125_WJC_METTL3_EV_vs_WT_F03.13687.13687.2 0.000425 20-Aug K.ATPSTYSGVFR[166.11].T sp|P48634|PRC2A_HUMAN 1 1194.5909 2.27 29611 13687 2 1194.590383 598.3027 Protein PRRC2A OS=Homo sapiens OX=9606 GN=PRRC2A PE=1 SV=3 8.79 2634.2 - 2.74E+06 - - - -0.3976 - 1.732 0.46 - 241 1 2 0 -0.0005 11 0 0 0 1.06E+08 4.65E+07 - - - 3.9243 0.9995 221125_WJC_METTL3_EV_vs_WT_F03.13688.13688.2 0.00711 16-Sep R.GLVGEIIKR.F "sp|P15531|NDKA_HUMAN,sp|P22392|NDKB_HUMAN,tr|Q32Q12|Q32Q12_HUMAN,tr|Q32Q12|Q32Q12_HUMAN,tr|J3KPD9|J3KPD9_HUMAN,tr|F6XY72|F6XY72_HUMAN,tr|E5RHP0|E5RHP0_HUMAN,tr|E7ERL0|E7ERL0_HUMAN,tr|C9K028|C9K028_HUMAN" 9 983.6128 1.28 29612 13688 2 983.610982 492.8137 Nucleoside diphosphate kinase A OS=Homo sapiens OX=9606 GN=NME1 PE=1 SV=1 8.75 2634.2 - 1.75E+06 - - - -1.8127 - 1.733 0.411 - 293.6 1 2 0 -0.0018 9 0 0 0 2.23E+08 1.74E+08 - - - 3.6668 0.9998 221125_WJC_METTL3_EV_vs_WT_F03.13689.13689.2 1.17E-05 18-Dec K.TISHVIIGLK[136.11].T "sp|Q9Y265|RUVB1_HUMAN,tr|E7ETR0|E7ETR0_HUMAN" 2 1087.6845 0.7 29613 13689 2 1087.683327 544.8495 RuvB-like 1 OS=Homo sapiens OX=9606 GN=RUVBL1 PE=1 SV=1 8.44 2634.4 - 1.40E+06 - - - -1.0601 - 2.141 0.448 - 363.8 1 2 0 -0.0012 10 0 0 0 1.66E+07 2.38E+07 - - - 4.4745 0.9998 221125_WJC_METTL3_EV_vs_WT_F03.13690.13690.2 0.0259 15/22 R.TIEYLQPNPASR.A "sp|Q99961|SH3G1_HUMAN,sp|Q99962|SH3G2_HUMAN,tr|M0R0I3|M0R0I3_HUMAN,tr|M0QYE0|M0QYE0_HUMAN" 4 1387.7096 1.87 29614 13690 2 1387.707883 694.8621 Endophilin-A2 OS=Homo sapiens OX=9606 GN=SH3GL1 PE=1 SV=1 5.66 2634.5 - 1.12E+06 - - - -1.2222 - 2.653 0.451 - 797.7 1 2 0 -0.0017 12 0 0 0 8.34E+07 4.45E+07 - - - 4.9388 0.9995 221125_WJC_METTL3_EV_vs_WT_F03.13691.13691.2 0.00626 13/24 K.IIDDSDSNLSVVK.K "sp|P0DJD0|RGPD1_HUMAN,sp|Q7Z3J3|RGPD4_HUMAN,sp|P49792|RBP2_HUMAN,sp|P0DJD1|RGPD2_HUMAN,sp|A6NKT7|RGPD3_HUMAN,tr|A0A286YES2|A0A286YES2_HUMAN,tr|F8VYC4|F8VYC4_HUMAN,tr|J3KNE0|J3KNE0_HUMAN,tr|A0A1W2PNU4|A0A1W2PNU4_HUMAN" 9 1403.7144 1.03 29615 13691 2 1403.716061 702.8645 RANBP2-like and GRIP domain-containing protein 1 OS=Homo sapiens OX=9606 GN=RGPD1 PE=2 SV=1 3.93 2634.6 - 1.02E+06 - - - 1.1904 - 1.814 0.382 - 330.6 1 2 0 0.0017 13 0 0 0 3.44E+07 3.33E+07 - - - 3.3904 1 221125_WJC_METTL3_EV_vs_WT_F03.13693.13693.2 6.42E-06 15/22 K.ILIANTGMDTDK.L "sp|P78371|TCPB_HUMAN,tr|F8VQ14|F8VQ14_HUMAN,tr|F5GWF6|F5GWF6_HUMAN" 3 1290.649 0.52 29616 13693 2 1290.646796 646.3318 T-complex protein 1 subunit beta OS=Homo sapiens OX=9606 GN=CCT2 PE=1 SV=4 4.21 2634.8 - 1.08E+07 - - - -1.6713 - 3.014 0.56 - 745.5 1 2 0 -0.0022 12 0 0 0 3.91E+08 7.58E+08 - - - 6.0794 0.9995 221125_WJC_METTL3_EV_vs_WT_F03.13694.13694.2 2.69E-05 22-Dec K.NAGVEGSLIVEK[136.11].L "sp|P10809|CH60_HUMAN,tr|A0A7I2V2X6|A0A7I2V2X6_HUMAN,tr|A0A7I2YQK6|A0A7I2YQK6_HUMAN,tr|A0A7I2V599|A0A7I2V599_HUMAN" 4 1222.6649 2 29617 13694 2 1222.667046 612.3397 "60 kDa heat shock protein, mitochondrial OS=Homo sapiens OX=9606 GN=HSPD1 PE=1 SV=2" 4.53 2634.9 - 2.65E+06 - - - 1.7822 - 2.296 0.363 - 444 1 2 0 0.0022 12 0 0 0 7.16E+07 3.58E+07 - - - 3.9084 0.9995 221125_WJC_METTL3_EV_vs_WT_F03.13695.13695.3 0.000922 13/40 R.LLASTLVHSVK.K "sp|Q9NYF8|BCLF1_HUMAN,tr|E9PKI6|E9PKI6_HUMAN,tr|A0A1W2PQ43|A0A1W2PQ43_HUMAN,tr|E9PK91|E9PK91_HUMAN,tr|E9PJA7|E9PJA7_HUMAN,tr|E9PK09|E9PK09_HUMAN,tr|E9PQN2|E9PQN2_HUMAN" 7 1166.7023 2.05 29618 13695 3 1166.70055 389.908 Bcl-2-associated transcription factor 1 OS=Homo sapiens OX=9606 GN=BCLAF1 PE=1 SV=2 8.76 2634.9 - 6.46E+07 - - - -1.5077 - 2.479 0.258 - 128 1 2 0 -0.0018 11 0 0 0 1.58E+10 7.74E+09 - - - 3.995 0.9997 221125_WJC_METTL3_EV_vs_WT_F03.13696.13696.2 0.00249 20-Oct K.GALTLSSPEVR.F "sp|Q9Y2L1|RRP44_HUMAN,tr|G3V1J5|G3V1J5_HUMAN" 2 1128.6139 1.82 29619 13696 2 1128.613144 565.3142 Exosome complex exonuclease RRP44 OS=Homo sapiens OX=9606 GN=DIS3 PE=1 SV=2 6 2635 - 9.32E+06 - - - -0.6592 - 2.239 0.318 - 344.2 1 2 0 -0.0007 11 0 0 0 4.94E+08 2.72E+08 - - - 3.57 0.9977 221125_WJC_METTL3_EV_vs_WT_F03.13697.13697.2 0.00375 16-Oct R.FQIATVTEK[136.11].G sp|P28070|PSB4_HUMAN 1 1043.5743 1.71 29620 13697 2 1043.577428 522.7944 Proteasome subunit beta type-4 OS=Homo sapiens OX=9606 GN=PSMB4 PE=1 SV=4 6 2635 - 5.08E+06 - - - 3.0348 - 1.661 0.344 - 285 1 2 0 0.0032 9 0 0 0 3.24E+08 1.90E+08 - - - 3.0488 0.9999 221125_WJC_METTL3_EV_vs_WT_F03.13698.13698.2 1.86E-05 20-Oct K.VLFSSNGGVVK[136.11].G "sp|P26599|PTBP1_HUMAN,tr|A0A0U1RRM4|A0A0U1RRM4_HUMAN,tr|A6NLN1|A6NLN1_HUMAN,tr|A0A0D9SF20|A0A0D9SF20_HUMAN,tr|A0A7I2V621|A0A7I2V621_HUMAN" 5 1113.6274 0.98 29621 13698 2 1113.626819 557.821 Polypyrimidine tract-binding protein 1 OS=Homo sapiens OX=9606 GN=PTBP1 PE=1 SV=1 8.72 2635 - 4.49E+06 - - - -0.4849 - 2.171 0.505 - 261.1 1 2 0 -0.0005 11 0 0 0 1.27E+09 1.29E+09 - - - 4.8678 0.9998 221125_WJC_METTL3_EV_vs_WT_F03.13699.13699.2 8.76E-05 20-Nov K.VLFSSNGGVVK.G "sp|P26599|PTBP1_HUMAN,tr|A0A0U1RRM4|A0A0U1RRM4_HUMAN,tr|A6NLN1|A6NLN1_HUMAN,tr|A0A0D9SF20|A0A0D9SF20_HUMAN,tr|A0A7I2V621|A0A7I2V621_HUMAN" 5 1105.6132 0.98 29622 13699 2 1105.611743 553.8139 Polypyrimidine tract-binding protein 1 OS=Homo sapiens OX=9606 GN=PTBP1 PE=1 SV=1 8.72 2635.1 - 3.27E+06 - - - -1.2807 - 2.119 0.518 - 335.2 1 2 0 -0.0014 11 0 0 0 1.27E+09 1.29E+09 - - - 4.898 0.9772 221125_WJC_METTL3_EV_vs_WT_F03.13700.13700.2 0.0118 16-Nov L.ASTLVHSVK[136.11].K "sp|Q9NYF8|BCLF1_HUMAN,tr|E9PKI6|E9PKI6_HUMAN,tr|A0A1W2PQ43|A0A1W2PQ43_HUMAN,tr|E9PK91|E9PK91_HUMAN,tr|E9PJA7|E9PJA7_HUMAN,tr|E9PK09|E9PK09_HUMAN,tr|E9PQN2|E9PQN2_HUMAN" 7 948.5484 2.09 29623 13700 2 948.547089 475.2815 Bcl-2-associated transcription factor 1 OS=Homo sapiens OX=9606 GN=BCLAF1 PE=1 SV=2 8.8 2635.2 - 3.11E+06 - - - -1.3621 - 2.102 0.339 - 772 1 1 0 -0.0013 9 0 0 0 1.32E+09 6.33E+08 - - - 3.6937 0.9989 221125_WJC_METTL3_EV_vs_WT_F03.13701.13701.2 0.00698 16-Aug R.GLVGEIIK[136.11]R[166.11].F "sp|P15531|NDKA_HUMAN,sp|P22392|NDKB_HUMAN,tr|Q32Q12|Q32Q12_HUMAN,tr|Q32Q12|Q32Q12_HUMAN,tr|J3KPD9|J3KPD9_HUMAN,tr|F6XY72|F6XY72_HUMAN,tr|E5RHP0|E5RHP0_HUMAN,tr|E7ERL0|E7ERL0_HUMAN,tr|C9K028|C9K028_HUMAN" 9 1001.6352 1.28 29624 13701 2 1001.634728 501.8249 Nucleoside diphosphate kinase A OS=Homo sapiens OX=9606 GN=NME1 PE=1 SV=1 8.75 2635.2 - 2.93E+06 - - - -0.5062 - 1.53 0.271 - 223.2 1 2 0 -0.0005 9 0 0 0 2.23E+08 1.74E+08 - - - 2.2728 0.9782 221125_WJC_METTL3_EV_vs_WT_F03.13702.13702.2 0.149 18-Oct L.LASTLVHSVK.K "sp|Q9NYF8|BCLF1_HUMAN,tr|E9PKI6|E9PKI6_HUMAN,tr|A0A1W2PQ43|A0A1W2PQ43_HUMAN,tr|E9PK91|E9PK91_HUMAN,tr|E9PJA7|E9PJA7_HUMAN,tr|E9PK09|E9PK09_HUMAN,tr|E9PQN2|E9PQN2_HUMAN" 7 1053.6182 2.15 29625 13702 2 1053.617835 527.8164 Bcl-2-associated transcription factor 1 OS=Homo sapiens OX=9606 GN=BCLAF1 PE=1 SV=2 8.76 2635.3 - 2.72E+06 - - - -0.3891 - 2.171 0.29 - 253.9 1 1 0 -0.0004 10 0 0 0 7.58E+08 3.53E+08 - - - 3.3466 0.9996 221125_WJC_METTL3_EV_vs_WT_F03.13703.13703.2 0.000249 24-Oct R.GPLPAAPPVAPER[166.11].Q "sp|Q9NQC3|RTN4_HUMAN,tr|F8W914|F8W914_HUMAN" 2 1280.7116 2.12 29626 13703 2 1280.713943 641.3631 Reticulon-4 OS=Homo sapiens OX=9606 GN=RTN4 PE=1 SV=2 6 2635.4 - 2.06E+06 - - - 1.7974 - 1.755 0.516 - 251.7 1 2 0 0.0023 13 0 0 0 1.24E+08 5.86E+07 - - - 4.295 0.9851 221125_WJC_METTL3_EV_vs_WT_F03.13704.13704.2 0.00169 18-Dec L.LASTLVHSVK[136.11].K "sp|Q9NYF8|BCLF1_HUMAN,tr|E9PKI6|E9PKI6_HUMAN,tr|A0A1W2PQ43|A0A1W2PQ43_HUMAN,tr|E9PK91|E9PK91_HUMAN,tr|E9PJA7|E9PJA7_HUMAN,tr|E9PK09|E9PK09_HUMAN,tr|E9PQN2|E9PQN2_HUMAN" 7 1061.6324 2.15 29627 13704 2 1061.630619 531.8235 Bcl-2-associated transcription factor 1 OS=Homo sapiens OX=9606 GN=BCLAF1 PE=1 SV=2 8.76 2635.5 - 1.17E+06 - - - -1.72 - 2.203 0.454 - 429.7 1 1 0 -0.0018 10 0 0 0 7.58E+08 3.53E+08 - - - 4.5983 0.9998 221125_WJC_METTL3_EV_vs_WT_F03.13707.13707.2 6.68E-05 18-Oct K.C[160.03]PFTGNVSIR[166.11].G "sp|P62280|RS11_HUMAN,tr|M0QZC5|M0QZC5_HUMAN" 2 1159.5683 0.92 29629 13707 2 1159.567237 580.7915 40S ribosomal protein S11 OS=Homo sapiens OX=9606 GN=RPS11 PE=1 SV=3 8.25 2635.8 - 1.01E+07 - - - -0.9581 - 1.688 0.502 - 419.4 1 2 0 -0.0011 10 0 0 0 1.24E+09 1.35E+09 - - - 4.2098 0.9998 221125_WJC_METTL3_EV_vs_WT_F03.13709.13709.2 0.000586 22-Dec K.TQVVAGTNYYIK.V "sp|P01040|CYTA_HUMAN,tr|C9J0E4|C9J0E4_HUMAN" 2 1355.7085 999 29630 13709 2 1355.706657 678.8615 Cystatin-A OS=Homo sapiens OX=9606 GN=CSTA PE=1 SV=1 8.17 2636 - 1.77E+07 - - - -1.3712 - 2.253 0.536 - 359.9 1 2 0 -0.0019 12 0 0 0 4.72E+08 0.00E+00 - - - 5.1365 0.9997 221125_WJC_METTL3_EV_vs_WT_F03.13710.13710.2 0.189 18-Oct K.YEELQITAGR.H "sp|P04264|K2C1_HUMAN,sp|P04259|K2C6B_HUMAN" 2 1178.5932 10584.03 29631 13710 2 1178.592714 590.3039 "Keratin, type II cytoskeletal 1 OS=Homo sapiens OX=9606 GN=KRT1 PE=1 SV=6" 4.53 2636.1 - 1.82E+07 - - - -0.3716 - 2.182 0.32 - 420.1 1 2 0 -0.0004 10 0 0 0 4.47E+10 4.23E+06 - - - 3.5823 0.9993 221125_WJC_METTL3_EV_vs_WT_F03.13711.13711.2 0.0353 16-Aug R.FQIATVTEK.G sp|P28070|PSB4_HUMAN 1 1035.5601 1.69 29632 13711 2 1035.559094 518.7873 Proteasome subunit beta type-4 OS=Homo sapiens OX=9606 GN=PSMB4 PE=1 SV=4 6 2636.1 - 1.19E+07 - - - -0.9338 - 1.733 0.305 - 177.5 1 2 0 -0.001 9 0 0 0 3.25E+08 1.92E+08 - - - 2.8842 0.9999 221125_WJC_METTL3_EV_vs_WT_F03.13713.13713.3 0.00323 16/40 R.ALQVALGAHLR.D sp|Q969Y2|GTPB3_HUMAN 1 1147.6826 1.74 29634 13713 3 1147.684255 383.5681 "tRNA modification GTPase GTPBP3, mitochondrial OS=Homo sapiens OX=9606 GN=GTPBP3 PE=1 SV=2" 9.8 2636.3 - 957304 - - - 1.4629 - 2.741 0.381 - 299.8 1 2 0 0.0017 11 0 0 0 3.91E+07 2.24E+07 - - - 5.6518 1 221125_WJC_METTL3_EV_vs_WT_F03.13714.13714.2 3.80E-05 15/30 R.PGPGLSSQTAGAAGWR.R sp|P38432|COIL_HUMAN 1 1511.7481 1.15 29635 13714 2 1511.747424 756.8813 Coilin OS=Homo sapiens OX=9606 GN=COIL PE=1 SV=1 10.18 2636.4 - 434521 - - - -0.4405 - 2.825 0.576 - 501.6 1 1 0 -0.0007 16 0 0 0 1.07E+07 9.34E+06 - - - 5.8483 0.9998 221125_WJC_METTL3_EV_vs_WT_F03.13717.13717.2 2.92E-05 22-Nov K.NAGVEGSLIVEK.L "sp|P10809|CH60_HUMAN,tr|A0A7I2V2X6|A0A7I2V2X6_HUMAN,tr|A0A7I2YQK6|A0A7I2YQK6_HUMAN,tr|A0A7I2V599|A0A7I2V599_HUMAN" 4 1214.6507 2.03 29636 13717 2 1214.651122 608.3326 "60 kDa heat shock protein, mitochondrial OS=Homo sapiens OX=9606 GN=HSPD1 PE=1 SV=2" 4.53 2636.8 - 3.23E+06 - - - 0.3746 - 1.979 0.496 - 265.6 1 2 0 0.0005 12 0 0 0 1.76E+08 8.70E+07 - - - 4.5003 0.9948 221125_WJC_METTL3_EV_vs_WT_F03.13718.13718.2 2.95E-05 13/22 K.AAELLQDEYSGR[166.11].G "sp|Q9BUK6|MSTO1_HUMAN,tr|A0A3B3IUD2|A0A3B3IUD2_HUMAN" 2 1360.6498 2.27 29637 13718 2 1360.641113 681.3322 Protein misato homolog 1 OS=Homo sapiens OX=9606 GN=MSTO1 PE=1 SV=1 4.14 2636.9 - 1.69E+06 - - - -6.4058 - 2.712 0.477 - 515.9 1 2 0 -0.0087 12 0 0 0 9.71E+07 4.27E+07 - - - 5.1865 0.9993 221125_WJC_METTL3_EV_vs_WT_F03.13727.13727.2 0.000931 20-Dec R.LEEEEQDILQR.L "sp|Q9HCM9|TRI39_HUMAN,tr|A0A0G2JKY0|A0A0G2JKY0_HUMAN,tr|A0A096LP39|A0A096LP39_HUMAN,tr|A0A140TA46|A0A140TA46_HUMAN,tr|A2AAZ6|A2AAZ6_HUMAN,tr|H0Y735|H0Y735_HUMAN" 6 1400.6783 3.14 29644 13727 2 1400.673824 701.3464 E3 ubiquitin-protein ligase TRIM39 OS=Homo sapiens OX=9606 GN=TRIM39 PE=1 SV=2 3.91 2638 - 1.49E+06 - - - -3.2227 - 2.635 0.419 - 634.4 1 2 0 -0.0045 11 0 0 0 5.93E+07 1.89E+07 - - - 4.7554 0.9997 221125_WJC_METTL3_EV_vs_WT_F03.13728.13728.2 0.0217 18-Nov R.AMGEQLLPGK[136.11].K "sp|Q14671|PUM1_HUMAN,tr|Q5T1Z8|Q5T1Z8_HUMAN,tr|H0YEH2|H0YEH2_HUMAN,tr|Q5T1Z4|Q5T1Z4_HUMAN" 4 1050.5623 3.56 29645 13728 2 1050.561905 526.2884 Pumilio homolog 1 OS=Homo sapiens OX=9606 GN=PUM1 PE=1 SV=3 6.05 2638.1 - 1.43E+06 - - - -0.3912 - 1.715 0.406 - 339.2 1 2 0 -0.0004 10 0 0 0 1.20E+08 3.38E+07 - - - 3.5453 1 221125_WJC_METTL3_EV_vs_WT_F03.13729.13729.2 1.78E-07 18/28 R.LAETQEEISAEVAAK[136.11].A "sp|Q9Y383|LC7L2_HUMAN,tr|A0A0A6YYJ8|A0A0A6YYJ8_HUMAN" 2 1595.8134 1.46 29646 13729 2 1595.810837 798.914 Putative RNA-binding protein Luc7-like 2 OS=Homo sapiens OX=9606 GN=LUC7L2 PE=1 SV=2 4.09 2638.3 - 744187 - - - -1.5948 - 3.323 0.518 - 1159 1 2 0 -0.0025 15 0 0 0 7.37E+07 5.06E+07 - - - 5.8185 0.9998 221125_WJC_METTL3_EV_vs_WT_F03.13731.13731.2 0.00336 24-Dec K.AIVAESLNNTSIK[136.11].G "sp|P35251|RFC1_HUMAN,tr|H0Y8U4|H0Y8U4_HUMAN" 2 1366.7547 5.22 29648 13731 2 1366.755663 684.3846 Replication factor C subunit 1 OS=Homo sapiens OX=9606 GN=RFC1 PE=1 SV=4 6.05 2638.5 - 628600 - - - 0.6717 - 2.36 0.387 - 275.3 1 2 0 0.0009 13 0 0 0 5.85E+07 1.12E+07 - - - 4.1029 0.97 221125_WJC_METTL3_EV_vs_WT_F03.13734.13734.2 0.00162 20-Nov R.MLIQENQELGR[166.11].Q sp|Q15007|FL2D_HUMAN 1 1339.6794 0.79 29649 13734 2 1339.671352 670.847 Pre-mRNA-splicing regulator WTAP OS=Homo sapiens OX=9606 GN=WTAP PE=1 SV=2 4.53 2638.9 - 2.36E+06 - - - -5.9738 - 1.848 0.252 - 375.3 1 2 0 -0.008 11 0 0 0 3.20E+07 4.05E+07 - - - 2.5611 1 221125_WJC_METTL3_EV_vs_WT_F03.13736.13736.2 7.06E-09 15/30 R.PGPGLSSQTAGAAGWR[166.11].R sp|P38432|COIL_HUMAN 1 1521.7564 1.15 29651 13736 2 1521.756572 761.8855 Coilin OS=Homo sapiens OX=9606 GN=COIL PE=1 SV=1 10.18 2639.2 - 536688 - - - 0.1393 - 3.318 0.629 - 370.4 1 1 0 0.0002 16 0 0 0 1.07E+07 9.34E+06 - - - 6.6354 0.9997 221125_WJC_METTL3_EV_vs_WT_F03.13741.13741.2 5.44 16-Nov R.ISASLLDSR.S "sp|O43402|EMC8_HUMAN,tr|M0R1B0|M0R1B0_HUMAN" 2 960.524 999 29653 13741 2 960.524539 481.2693 ER membrane protein complex subunit 8 OS=Homo sapiens OX=9606 GN=EMC8 PE=1 SV=1 5.84 2639.9 - 881633 - - - 0.5507 - 2.488 0.286 - 331.1 1 2 0 0.0005 9 0 0 0 2.35E+07 0.00E+00 - - - 3.7902 0.9987 221125_WJC_METTL3_EV_vs_WT_F03.13745.13745.2 0.00014 16/26 R.TAAALAPASLTSAR[166.11].M sp|Q9UQ35|SRRM2_HUMAN 1 1309.7229 1.24 29655 13745 2 1309.717538 655.8687 Serine\arginine repetitive matrix protein 2 OS=Homo sapiens OX=9606 GN=SRRM2 PE=1 SV=2 9.41 2640.4 - 1.64E+06 - - - -4.12 - 2.675 0.443 - 715.7 1 2 0 -0.0054 14 0 0 0 6.94E+07 5.60E+07 - - - 4.7805 1 221125_WJC_METTL3_EV_vs_WT_F03.13746.13746.2 1.17E-08 18/28 R.LAETQEEISAEVAAK.A "sp|Q9Y383|LC7L2_HUMAN,tr|A0A0A6YYJ8|A0A0A6YYJ8_HUMAN" 2 1587.7992 1.43 29656 13746 2 1587.79567 794.9069 Putative RNA-binding protein Luc7-like 2 OS=Homo sapiens OX=9606 GN=LUC7L2 PE=1 SV=2 4.09 2640.6 - 1.96E+06 - - - -2.2119 - 3.49 0.552 - 1254.9 1 2 0 -0.0035 15 0 0 0 7.26E+07 5.06E+07 - - - 6.1899 0.9998 221125_WJC_METTL3_EV_vs_WT_F03.13750.13750.2 2.54E-06 20-Oct K.ETTIDGEELVK.L "sp|P52732|KIF11_HUMAN,tr|A0A7I2YQY4|A0A7I2YQY4_HUMAN,tr|A0A7I2V3A9|A0A7I2V3A9_HUMAN,tr|A0A7I2V3V3|A0A7I2V3V3_HUMAN" 4 1232.6136 4.77 29658 13750 2 1232.611401 617.3141 Kinesin-like protein KIF11 OS=Homo sapiens OX=9606 GN=KIF11 PE=1 SV=2 4 2641 - 1.10E+08 - - - -1.7946 - 2.016 0.529 - 387 1 2 0 -0.0022 11 0 0 0 2.98E+09 6.24E+08 - - - 4.8442 0.999 221125_WJC_METTL3_EV_vs_WT_F03.13752.13752.2 0.00412 16-Sep R.YLDGLTAER.T sp|P35908|K22E_HUMAN 1 1036.5189 538.99 29660 13752 2 1036.517079 519.2667 "Keratin, type II cytoskeletal 2 epidermal OS=Homo sapiens OX=9606 GN=KRT2 PE=1 SV=2" 4.37 2641.1 - 1.11E+07 - - - -1.781 - 1.508 0.367 - 216.8 1 2 0 -0.0018 9 0 0 0 6.11E+08 1.13E+06 - - - 2.9395 0.9943 221125_WJC_METTL3_EV_vs_WT_F03.13756.13756.2 9.88E-05 20-Nov R.LEEEEQDILQR[166.11].L "sp|Q9HCM9|TRI39_HUMAN,tr|A0A0G2JKY0|A0A0G2JKY0_HUMAN,tr|A0A096LP39|A0A096LP39_HUMAN,tr|A0A140TA46|A0A140TA46_HUMAN,tr|A2AAZ6|A2AAZ6_HUMAN,tr|H0Y735|H0Y735_HUMAN" 6 1410.6866 3.12 29662 13756 2 1410.677803 706.3506 E3 ubiquitin-protein ligase TRIM39 OS=Homo sapiens OX=9606 GN=TRIM39 PE=1 SV=2 3.91 2641.6 - 918149 - - - -6.2416 - 2.49 0.446 - 596.5 1 2 0 -0.0088 11 0 0 0 5.89E+07 1.89E+07 - - - 4.8003 0.9996 221125_WJC_METTL3_EV_vs_WT_F03.13758.13758.2 3.91E-05 20-Aug K.ETTIDGEELVK[136.11].L "sp|P52732|KIF11_HUMAN,tr|A0A7I2YQY4|A0A7I2YQY4_HUMAN,tr|A0A7I2V3A9|A0A7I2V3A9_HUMAN,tr|A0A7I2V3V3|A0A7I2V3V3_HUMAN" 4 1240.6278 4.77 29663 13758 2 1240.625327 621.3212 Kinesin-like protein KIF11 OS=Homo sapiens OX=9606 GN=KIF11 PE=1 SV=2 4 2641.9 - 2.04E+07 - - - -2.0038 - 1.82 0.497 - 210.5 1 2 0 -0.0025 11 0 0 0 2.98E+09 6.24E+08 - - - 4.3311 0.9996 221125_WJC_METTL3_EV_vs_WT_F03.13763.13763.2 0.00189 20-Oct K.EITALAPSTMK.L "sp|P63261|ACTG_HUMAN,sp|P68133|ACTS_HUMAN,sp|P62736|ACTA_HUMAN,sp|P68032|ACTC_HUMAN,sp|P60709|ACTB_HUMAN,sp|P63267|ACTH_HUMAN,tr|A0A2R8YFE2|A0A2R8YFE2_HUMAN,tr|A0A804GS07|A0A804GS07_HUMAN,tr|E7EVS6|E7EVS6_HUMAN,tr|A0A6Q8PFE4|A0A6Q8PFE4_HUMAN,tr|A0A804HKV3|A0A804HKV3_HUMAN,tr|I3L4N8|I3L4N8_HUMAN,tr|A6NL76|A6NL76_HUMAN" 13 1160.6111 0.99 29667 13763 2 1160.610986 581.3128 "Actin, cytoplasmic 2 OS=Homo sapiens OX=9606 GN=ACTG1 PE=1 SV=1" 6.1 2642.4 - 3.64E+07 - - - -0.1068 - 2.071 0.316 - 282 1 2 0 -0.0001 11 0 0 0 1.17E+09 1.19E+09 - - - 3.3444 0.98 221125_WJC_METTL3_EV_vs_WT_F03.13764.13764.2 0.0019 16-Oct L.ASTLVHSVK.K "sp|Q9NYF8|BCLF1_HUMAN,tr|E9PKI6|E9PKI6_HUMAN,tr|A0A1W2PQ43|A0A1W2PQ43_HUMAN,tr|E9PK91|E9PK91_HUMAN,tr|E9PJA7|E9PJA7_HUMAN,tr|E9PK09|E9PK09_HUMAN,tr|E9PQN2|E9PQN2_HUMAN" 7 940.5342 2.08 29668 13764 2 940.532438 471.2744 Bcl-2-associated transcription factor 1 OS=Homo sapiens OX=9606 GN=BCLAF1 PE=1 SV=2 8.8 2642.4 - 3.27E+07 - - - -1.8532 - 2.003 0.436 - 568.2 1 1 0 -0.0017 9 0 0 0 1.32E+09 6.32E+08 - - - 4.2704 0.9998 221125_WJC_METTL3_EV_vs_WT_F03.13768.13768.2 3.27E-06 13/24 K.YGVNPGPIVGTTR[166.11].K "sp|P42166|LAP2A_HUMAN,sp|P42167|LAP2B_HUMAN,tr|G5E972|G5E972_HUMAN,tr|H0YJH7|H0YJH7_HUMAN" 4 1339.7124 1.14 29670 13768 2 1339.709767 670.8635 "Lamina-associated polypeptide 2, isoform alpha OS=Homo sapiens OX=9606 GN=TMPO PE=1 SV=2" 8.75 2642.9 - 3.16E+06 - - - -1.943 - 2.443 0.484 - 484.7 1 2 0 -0.0026 13 0 0 0 3.34E+08 2.95E+08 - - - 4.9075 0.9998 221125_WJC_METTL3_EV_vs_WT_F03.13769.13769.2 4.81E-06 24-Sep K.YGVNPGPIVGTTR.K "sp|P42166|LAP2A_HUMAN,sp|P42167|LAP2B_HUMAN,tr|G5E972|G5E972_HUMAN,tr|H0YJH7|H0YJH7_HUMAN" 4 1329.7041 1.06 29671 13769 2 1329.702827 665.8593 "Lamina-associated polypeptide 2, isoform alpha OS=Homo sapiens OX=9606 GN=TMPO PE=1 SV=2" 8.75 2643 - 3.02E+06 - - - -0.9574 - 1.987 0.513 - 218 1 2 0 -0.0013 13 0 0 0 3.11E+08 2.94E+08 - - - 4.5919 0.9994 221125_WJC_METTL3_EV_vs_WT_F03.13777.13777.2 0.00152 18-Nov K.SGTYLQGTFR[166.11].A "sp|Q9Y2L1|RRP44_HUMAN,tr|F2Z2C0|F2Z2C0_HUMAN,tr|G3V1J5|G3V1J5_HUMAN" 3 1138.5646 1.51 29677 13777 2 1138.564599 570.2896 Exosome complex exonuclease RRP44 OS=Homo sapiens OX=9606 GN=DIS3 PE=1 SV=2 8.46 2643.9 - 4.96E+06 - - - -0.0386 - 1.863 0.279 - 557.5 1 2 0 0 10 0 0 0 4.15E+08 2.75E+08 - - - 2.8384 0.9997 221125_WJC_METTL3_EV_vs_WT_F03.13778.13778.2 2.78E-05 20-Nov K.LGEMWSEQSAK[136.11].D sp|P26583|HMGB2_HUMAN 1 1272.59 0.3 29678 13778 2 1272.587431 637.3023 High mobility group protein B2 OS=Homo sapiens OX=9606 GN=HMGB2 PE=1 SV=2 4.53 2644 - 2.81E+06 - - - -2.0093 - 1.969 0.514 - 424.8 1 2 0 -0.0026 11 0 0 0 2.99E+07 1.01E+08 - - - 4.6695 0.9238 221125_WJC_METTL3_EV_vs_WT_F03.13784.13784.2 0.0159 18-Sep M.AAASIANIVK[136.11].S "sp|P17987|TCPA_HUMAN,tr|F5H726|F5H726_HUMAN,tr|F5H136|F5H136_HUMAN,tr|F5GZI8|F5GZI8_HUMAN,tr|E7ERF2|E7ERF2_HUMAN,tr|F5H676|F5H676_HUMAN,tr|F5GYL4|F5GYL4_HUMAN" 7 964.5797 0.51 29682 13784 2 964.577089 483.2971 T-complex protein 1 subunit alpha OS=Homo sapiens OX=9606 GN=TCP1 PE=1 SV=1 8.8 2644.8 - 1.27E+06 - - - -2.6872 - 1.861 0.341 - 228.4 1 1 0 -0.0026 10 0 0 0 1.91E+07 3.71E+07 - - - 3.2925 0.9996 221125_WJC_METTL3_EV_vs_WT_F03.13788.13788.2 0.00426 20-Oct K.LGEMWSEQSAK.D sp|P26583|HMGB2_HUMAN 1 1264.5758 0.3 29684 13788 2 1264.577633 633.2952 High mobility group protein B2 OS=Homo sapiens OX=9606 GN=HMGB2 PE=1 SV=2 4.53 2645.4 - 620661 - - - 1.459 - 2.131 0.356 - 459.6 1 2 0 0.0018 11 0 0 0 3.04E+07 1.01E+08 - - - 3.7166 0.9983 221125_WJC_METTL3_EV_vs_WT_F03.13792.13792.2 0.0224 22-Nov K.LYQSATQAVFQK.R "sp|Q92696|PGTA_HUMAN,tr|H0YKP6|H0YKP6_HUMAN,tr|H0YLH3|H0YLH3_HUMAN" 3 1382.7194 1.13 29686 13792 2 1382.715733 692.367 Geranylgeranyl transferase type-2 subunit alpha OS=Homo sapiens OX=9606 GN=RABGGTA PE=1 SV=2 8.59 2645.8 - 1.31E+06 - - - -2.6629 - 1.947 0.307 - 272 1 2 0 -0.0037 12 0 0 0 3.72E+07 3.30E+07 - - - 3.0605 0.9992 221125_WJC_METTL3_EV_vs_WT_F03.13793.13793.2 0.00156 18-Aug R.AQPGDYVLVK[136.11].L "sp|Q96SZ6|CK5P1_HUMAN,tr|H0Y721|H0Y721_HUMAN" 2 1096.6008 0.53 29687 13793 2 1096.599358 549.3077 Mitochondrial tRNA methylthiotransferase CDK5RAP1 OS=Homo sapiens OX=9606 GN=CDK5RAP1 PE=1 SV=2 5.88 2645.9 - 1.30E+06 - - - -1.3241 - 1.501 0.365 - 182 1 2 0 -0.0015 10 0 0 0 9.85E+06 1.86E+07 - - - 2.8701 1 221125_WJC_METTL3_EV_vs_WT_F03.13795.13795.2 2.74E-07 15/26 R.AYGPGIEPTGNMVK.K "sp|P21333|FLNA_HUMAN,tr|A0A7P0NMY4|A0A7P0NMY4_HUMAN,tr|Q60FE5|Q60FE5_HUMAN,tr|A0A7I2V3E6|A0A7I2V3E6_HUMAN,tr|A0A087WWY3|A0A087WWY3_HUMAN,tr|F8WE98|F8WE98_HUMAN" 6 1432.7021 1.65 29689 13795 2 1432.698918 717.3583 Filamin-A OS=Homo sapiens OX=9606 GN=FLNA PE=1 SV=4 6.05 2646.2 - 1.20E+06 - - - -2.1868 - 2.43 0.613 - 591 1 2 0 -0.0031 14 0 0 0 4.38E+07 2.66E+07 - - - 5.7958 0.9997 221125_WJC_METTL3_EV_vs_WT_F03.13800.13800.2 0.00435 16-Oct K.IQEILTQVK[136.11].Q sp|O00425|IF2B3_HUMAN 1 1078.6478 1.75 29692 13800 2 1078.647726 540.3312 Insulin-like growth factor 2 mRNA-binding protein 3 OS=Homo sapiens OX=9606 GN=IGF2BP3 PE=1 SV=2 6 2646.7 - 1.99E+06 - - - -0.0315 - 2.184 0.313 - 234.9 1 2 0 0 9 0 0 0 9.72E+07 5.54E+07 - - - 3.6127 0.9952 221125_WJC_METTL3_EV_vs_WT_F03.13801.13801.2 0.00126 18-Sep K.LSGEAFDINK[136.11].L sp|Q8TEQ6|GEMI5_HUMAN 1 1100.5593 0.46 29693 13801 2 1100.56429 551.2869 Gem-associated protein 5 OS=Homo sapiens OX=9606 GN=GEMIN5 PE=1 SV=3 4.37 2646.9 - 1.36E+06 - - - 4.4986 - 1.907 0.348 - 159.7 1 2 0 0.005 10 0 0 0 1.51E+07 3.30E+07 - - - 3.4116 0.9995 221125_WJC_METTL3_EV_vs_WT_F03.13804.13804.2 0.00393 16-Aug R.SQSFFAAAR[166.11].A "sp|O14654|IRS4_HUMAN,tr|A0A804CF45|A0A804CF45_HUMAN" 2 993.4907 1.01 29694 13804 2 993.489731 497.7527 Insulin receptor substrate 4 OS=Homo sapiens OX=9606 GN=IRS4 PE=1 SV=1 9.47 2647.3 - 1.31E+07 - - - -1.0247 - 1.703 0.348 - 242.9 1 2 0 -0.001 9 0 0 0 3.10E+08 3.08E+08 - - - 3.1512 0.9996 221125_WJC_METTL3_EV_vs_WT_F03.13805.13805.2 0.093 16-Oct K.IQEILTQVK.Q sp|O00425|IF2B3_HUMAN 1 1070.6336 1.74 29695 13805 2 1070.633684 536.3241 Insulin-like growth factor 2 mRNA-binding protein 3 OS=Homo sapiens OX=9606 GN=IGF2BP3 PE=1 SV=2 6 2647.3 - 3.03E+06 - - - 0.1158 - 1.983 0.293 - 211.5 1 2 0 0.0001 9 0 0 0 9.72E+07 5.59E+07 - - - 3.1857 0.9994 221125_WJC_METTL3_EV_vs_WT_F03.13807.13807.2 0.00123 22-Oct R.FLEQQNQVLETK.W "sp|Q86Y46|K2C73_HUMAN,sp|Q7RTS7|K2C74_HUMAN,sp|Q3SY84|K2C71_HUMAN,sp|Q14CN4|K2C72_HUMAN,tr|H0YIG3|H0YIG3_HUMAN,tr|F8W1S1|F8W1S1_HUMAN" 6 1475.762 999 29697 13807 2 1475.765798 738.8883 "Keratin, type II cytoskeletal 73 OS=Homo sapiens OX=9606 GN=KRT73 PE=1 SV=1" 4.53 2647.6 - 1.77E+06 - - - 2.5675 - 2.083 0.457 - 255.8 1 2 0 0.0038 12 0 0 0 4.12E+07 0.00E+00 - - - 4.346 0.9966 221125_WJC_METTL3_EV_vs_WT_F03.13809.13809.2 0.0121 14-Aug K.QTPSDFLK.Q sp|P62312|LSM6_HUMAN 1 934.476 2.05 29699 13809 2 934.479225 468.2453 U6 snRNA-associated Sm-like protein LSm6 OS=Homo sapiens OX=9606 GN=LSM6 PE=1 SV=1 5.84 2647.8 - 1.71E+06 - - - 3.4543 - 1.471 0.372 - 216.8 1 2 0 0.0032 8 0 0 0 4.16E+07 2.03E+07 - - - 2.9516 0.9993 221125_WJC_METTL3_EV_vs_WT_F03.13810.13810.2 0.00105 14-Sep R.SMSFQGIR.Q sp|P15924|DESP_HUMAN 1 924.4487 22.57 29700 13810 2 924.446349 463.2316 Desmoplakin OS=Homo sapiens OX=9606 GN=DSP PE=1 SV=3 9.47 2647.9 - 866694 - - - -2.5832 - 1.445 0.512 - 288.1 1 2 0 -0.0024 8 0 0 0 3.60E+07 1.59E+06 - - - 3.9321 1 221125_WJC_METTL3_EV_vs_WT_F03.13812.13812.2 3.52E-08 13/20 R.FDGGVEAIATR[166.11].Q sp|P33908|MA1A1_HUMAN 1 1144.5752 0.85 29701 13812 2 1144.569375 573.2949 "Mannosyl-oligosaccharide 1,2-alpha-mannosidase IA OS=Homo sapiens OX=9606 GN=MAN1A1 PE=1 SV=3" 4.37 2648.2 - 2.87E+06 - - - -5.0953 - 2.671 0.588 - 510.6 1 2 0 -0.0058 11 0 0 0 8.21E+07 9.66E+07 - - - 6.0399 0.9998 221125_WJC_METTL3_EV_vs_WT_F03.13814.13814.2 0.000258 24-Nov R.SILSPGGSC[160.03]GPIK[136.11].V "sp|P78347|GTF2I_HUMAN,tr|A0A494C1K3|A0A494C1K3_HUMAN" 2 1279.6686 1.4 29702 13814 2 1279.66646 640.8416 General transcription factor II-I OS=Homo sapiens OX=9606 GN=GTF2I PE=1 SV=2 7.94 2648.4 - 6.69E+06 - - - -1.6512 - 2.339 0.488 - 332.1 1 2 0 -0.0021 13 0 0 0 7.93E+08 5.67E+08 - - - 4.8255 0.9861 221125_WJC_METTL3_EV_vs_WT_F03.13816.13816.2 0.09 14-Jul R.LLGQIVDR.C sp|Q96I24|FUBP3_HUMAN 1 912.5393 2.93 29704 13816 2 912.541802 457.2769 Far upstream element-binding protein 3 OS=Homo sapiens OX=9606 GN=FUBP3 PE=1 SV=2 5.84 2648.6 - 593740 - - - 2.7791 - 1.359 0.187 - 105.5 1 2 0 0.0025 8 0 0 0 2.08E+07 7.09E+06 - - - 1.3465 0.9007 221125_WJC_METTL3_EV_vs_WT_F03.13818.13818.2 0.0094 14-Aug A.STLVHSVK.K "sp|Q9NYF8|BCLF1_HUMAN,tr|E9PKI6|E9PKI6_HUMAN,tr|A0A1W2PQ43|A0A1W2PQ43_HUMAN,tr|E9PK91|E9PK91_HUMAN,tr|E9PJA7|E9PJA7_HUMAN,tr|E9PK09|E9PK09_HUMAN,tr|E9PQN2|E9PQN2_HUMAN" 7 869.4971 1.9 29705 13818 2 869.495792 435.7558 Bcl-2-associated transcription factor 1 OS=Homo sapiens OX=9606 GN=BCLAF1 PE=1 SV=2 8.49 2648.9 - 2.33E+06 - - - -1.4664 - 1.616 0.233 - 255.9 1 1 0 -0.0013 8 0 0 0 1.66E+08 8.73E+07 - - - 2.2091 0.9997 221125_WJC_METTL3_EV_vs_WT_F03.13821.13821.2 0.00229 16-Sep R.SQSFFAAAR.A "sp|O14654|IRS4_HUMAN,tr|A0A804CF45|A0A804CF45_HUMAN" 2 983.4825 1.01 29707 13821 2 983.481 492.7485 Insulin receptor substrate 4 OS=Homo sapiens OX=9606 GN=IRS4 PE=1 SV=1 9.47 2649.1 - 1.40E+07 - - - -1.5038 - 1.882 0.447 - 405.3 1 2 0 -0.0015 9 0 0 0 3.10E+08 3.08E+08 - - - 4.1715 0.9822 221125_WJC_METTL3_EV_vs_WT_F03.13822.13822.2 3.07E-05 22-Nov K.LVEALC[160.03]AEHQIN.L sp|P25398|RS12_HUMAN 1 1395.6816 - 29708 13822 2 1395.680926 698.8481 40S ribosomal protein S12 OS=Homo sapiens OX=9606 GN=RPS12 PE=1 SV=3 4.51 2649.2 - 1.71E+06 - - - -0.5187 - 2.269 0.326 - 253.4 1 1 0 -0.0007 12 0 0 0 - - - - - 3.6044 0.9097 221125_WJC_METTL3_EV_vs_WT_F03.13823.13823.3 0.00763 14/44 A.FKPAASPLTSLR.Q sp|Q92615|LAR4B_HUMAN 1 1286.7347 1.33 29709 13823 3 1286.734355 429.9188 La-related protein 4B OS=Homo sapiens OX=9606 GN=LARP4B PE=1 SV=3 11 2649.3 - 1.35E+06 - - - -0.2464 - 2.162 0.24 - 198.2 1 1 0 -0.0003 12 0 0 0 3.35E+07 2.51E+07 - - - 3.3529 0.9999 221125_WJC_METTL3_EV_vs_WT_F03.13824.13824.2 5.25E-05 22-Nov K.VYETDNNIVVYK.G "sp|Q03393|PTPS_HUMAN,tr|E9PNN3|E9PNN3_HUMAN" 2 1455.7246 11.44 29710 13824 2 1455.723789 728.8696 6-pyruvoyl tetrahydrobiopterin synthase OS=Homo sapiens OX=9606 GN=PTS PE=1 SV=1 4.37 2649.4 - 1.28E+06 - - - -0.5296 - 2.436 0.524 - 255.9 1 2 0 -0.0008 12 0 0 0 6.15E+07 5.38E+06 - - - 5.2537 0.9999 221125_WJC_METTL3_EV_vs_WT_F03.13828.13828.2 3.14E-05 16-Sep K.DVDNAYMIK.V sp|P35908|K22E_HUMAN 1 1067.4957 2616.51 29712 13828 2 1067.494688 534.7551 "Keratin, type II cytoskeletal 2 epidermal OS=Homo sapiens OX=9606 GN=KRT2 PE=1 SV=2" 4.21 2650 - 7.89E+06 - - - -0.9911 - 1.869 0.551 - 164.5 1 2 0 -0.0011 9 0 0 0 6.88E+08 2.63E+05 - - - 4.9197 0.9995 221125_WJC_METTL3_EV_vs_WT_F03.13829.13829.2 0.163 18-Oct R.QEPLLIGSTK.S "sp|P49327|FAS_HUMAN,tr|A0A0U1RQF0|A0A0U1RQF0_HUMAN" 2 1084.6128 0.9 29713 13829 2 1084.613131 543.3137 Fatty acid synthase OS=Homo sapiens OX=9606 GN=FASN PE=1 SV=3 6 2650.1 - 1.37E+06 - - - 0.2821 - 1.919 0.288 - 277.5 1 2 0 0.0003 10 0 0 0 1.06E+08 1.17E+08 - - - 2.9875 0.9876 221125_WJC_METTL3_EV_vs_WT_F03.13830.13830.2 0.386 12-Aug R.LQLELSK.V "sp|P02545|LMNA_HUMAN,sp|Q5ST30|SYVM_HUMAN,tr|A0A6Q8PF80|A0A6Q8PF80_HUMAN,tr|B7ZL25|B7ZL25_HUMAN,tr|A0A804HL68|A0A804HL68_HUMAN,tr|A0A0G2JIA5|A0A0G2JIA5_HUMAN,tr|A0A140TA45|A0A140TA45_HUMAN,tr|A0A140TA40|A0A140TA40_HUMAN,tr|A0A6Q8PFM1|A0A6Q8PFM1_HUMAN,tr|A0A6Q8PF59|A0A6Q8PF59_HUMAN,tr|A0A6Q8PFJ0|A0A6Q8PFJ0_HUMAN,tr|A0A6Q8PHQ9|A0A6Q8PHQ9_HUMAN,tr|B4E0K6|B4E0K6_HUMAN,tr|A0A140T8Y0|A0A140T8Y0_HUMAN,tr|A0A6Q8PGH0|A0A6Q8PGH0_HUMAN,tr|A0A0A0MTG1|A0A0A0MTG1_HUMAN,tr|A0A0G2JL52|A0A0G2JL52_HUMAN,tr|Q3BDU5|Q3BDU5_HUMAN,tr|A0A140TA35|A0A140TA35_HUMAN,tr|A0A140TA36|A0A140TA36_HUMAN" 20 829.4909 3.64 29714 13830 2 829.489554 415.7527 Prelamin-A\C OS=Homo sapiens OX=9606 GN=LMNA PE=1 SV=1 6 2650.2 - 2.00E+06 - - - -1.6456 - 1.616 0.055 - 188.6 2 2 0 -0.0014 7 0 0 0 4.15E+07 1.14E+07 - - - 0.8331 0.9176 221125_WJC_METTL3_EV_vs_WT_F03.13832.13832.2 0.678 18-Sep K.LSGEAFDINK.L sp|Q8TEQ6|GEMI5_HUMAN 1 1092.5451 0.46 29716 13832 2 1092.549709 547.2798 Gem-associated protein 5 OS=Homo sapiens OX=9606 GN=GEMIN5 PE=1 SV=3 4.37 2650.3 - 1.30E+06 - - - 4.1829 - 1.217 0.177 - 119.5 2 2 0 0.0046 10 0 0 0 1.48E+07 3.22E+07 - - - 0.7606 0.9992 221125_WJC_METTL3_EV_vs_WT_F03.13834.13834.2 0.015 13/22 R.TIYAGNALC[160.03]TVK.C "sp|P13804|ETFA_HUMAN,tr|H0YK49|H0YK49_HUMAN,tr|H0YL12|H0YL12_HUMAN,tr|H0YKF0|H0YKF0_HUMAN,tr|H0YLU7|H0YLU7_HUMAN,tr|H0YNX6|H0YNX6_HUMAN" 6 1309.67 1.22 29718 13834 2 1309.66599 655.8423 "Electron transfer flavoprotein subunit alpha, mitochondrial OS=Homo sapiens OX=9606 GN=ETFA PE=1 SV=1" 7.86 2650.5 - 834151 - - - -3.0794 - 2.2 0.429 - 399.4 1 2 0 -0.004 12 0 0 0 9.96E+07 8.17E+07 - - - 4.2829 0.9999 221125_WJC_METTL3_EV_vs_WT_F03.13835.13835.2 5.36E-06 22-Dec K.LYQSATQAVFQK[136.11].R "sp|Q92696|PGTA_HUMAN,tr|H0YKP6|H0YKP6_HUMAN,tr|H0YLH3|H0YLH3_HUMAN" 3 1390.7336 1.82 29719 13835 2 1390.732003 696.3741 Geranylgeranyl transferase type-2 subunit alpha OS=Homo sapiens OX=9606 GN=RABGGTA PE=1 SV=2 8.59 2650.6 - 773218 - - - -1.1591 - 2.218 0.554 - 425.8 1 2 0 -0.0016 12 0 0 0 3.63E+07 2.00E+07 - - - 5.2283 0.9999 221125_WJC_METTL3_EV_vs_WT_F03.13838.13838.2 6.17E-06 18-Nov R.QDLTTLDVTK.L "sp|Q2VIR3|IF2GL_HUMAN,sp|P41091|IF2G_HUMAN,tr|H7BZU1|H7BZU1_HUMAN" 3 1132.5976 0.54 29720 13838 2 1132.596297 567.3061 Eukaryotic translation initiation factor 2 subunit 3B OS=Homo sapiens OX=9606 GN=EIF2S3B PE=2 SV=2 4.21 2651 - 6.46E+06 - - - -1.1231 - 2.591 0.49 - 492.5 1 2 0 -0.0013 10 0 0 0 2.16E+08 4.03E+08 - - - 5.3172 0.9997 221125_WJC_METTL3_EV_vs_WT_F03.13839.13839.2 0.00577 18-Sep K.TLIEAGLPQK[136.11].V "sp|O43390|HNRPR_HUMAN,tr|A0A6Q8PH35|A0A6Q8PH35_HUMAN" 2 1076.6321 1.42 29721 13839 2 1076.631367 539.3233 Heterogeneous nuclear ribonucleoprotein R OS=Homo sapiens OX=9606 GN=HNRNPR PE=1 SV=1 5.66 2651.1 - 3.91E+06 - - - -0.6901 - 1.652 0.433 - 224.2 1 2 0 -0.0007 10 0 0 0 2.77E+08 1.95E+08 - - - 3.6401 0.9997 221125_WJC_METTL3_EV_vs_WT_F03.13840.13840.2 0.000577 18-Oct R.QEPLLIGSTK[136.11].S "sp|P49327|FAS_HUMAN,tr|A0A0U1RQF0|A0A0U1RQF0_HUMAN" 2 1092.627 0.93 29722 13840 2 1092.625986 547.3208 Fatty acid synthase OS=Homo sapiens OX=9606 GN=FASN PE=1 SV=3 6 2651.1 - 2.00E+06 - - - -0.9509 - 1.674 0.454 - 296.2 1 2 0 -0.001 10 0 0 0 1.05E+08 1.12E+08 - - - 3.832 0.9998 221125_WJC_METTL3_EV_vs_WT_F03.13841.13841.2 0.000586 16-Aug K.EFVSASFDK.S "sp|Q9NV06|DCA13_HUMAN,tr|A0A087WT20|A0A087WT20_HUMAN,tr|A0A087X1F8|A0A087X1F8_HUMAN" 3 1028.4815 1.47 29723 13841 2 1028.480077 515.248 DDB1- and CUL4-associated factor 13 OS=Homo sapiens OX=9606 GN=DCAF13 PE=1 SV=2 4.37 2651.3 - 1.71E+06 - - - -1.3603 - 1.879 0.477 - 254.2 1 2 0 -0.0014 9 0 0 0 2.75E+07 1.87E+07 - - - 4.3884 0.9649 221125_WJC_METTL3_EV_vs_WT_F03.13842.13842.2 0.000534 14-Jun R.NGVMPSHF.S "sp|P39019|RS19_HUMAN,tr|A0A075B6E2|A0A075B6E2_HUMAN" 2 887.396 - 29724 13842 2 887.394282 444.7053 40S ribosomal protein S19 OS=Homo sapiens OX=9606 GN=RPS19 PE=1 SV=2 6.74 2651.4 - 1.27E+06 - - - -1.9056 - 1.372 0.485 - 126.5 1 1 0 -0.0017 8 0 0 0 - - - - - 3.5765 0.9995 221125_WJC_METTL3_EV_vs_WT_F03.13843.13843.2 0.000213 18-Aug K.DC[160.03]EDPNPLIR[166.11].A "sp|P63010|AP2B1_HUMAN,sp|Q10567|AP1B1_HUMAN,tr|K7ERB2|K7ERB2_HUMAN,tr|A0A087WZQ6|A0A087WZQ6_HUMAN,tr|K7EN71|K7EN71_HUMAN,tr|C9J1E7|C9J1E7_HUMAN,tr|A0A087WU93|A0A087WU93_HUMAN" 7 1237.5637 0.89 29725 13843 2 1237.566549 619.7891 AP-2 complex subunit beta OS=Homo sapiens OX=9606 GN=AP2B1 PE=1 SV=1 4.03 2651.5 - 978992 - - - 2.3368 - 1.625 0.531 - 174 1 2 0 0.0029 10 0 0 0 2.56E+07 2.87E+07 - - - 4.3173 0.9998 221125_WJC_METTL3_EV_vs_WT_F03.13845.13845.2 8.24E-05 26-Dec K.ELSTTLNADEAVTR[166.11].G "sp|P34932|HSP74_HUMAN,tr|A0A087WTS8|A0A087WTS8_HUMAN,tr|A0A087WYC1|A0A087WYC1_HUMAN" 3 1528.7608 0.08 29727 13845 2 1528.757905 765.3877 Heat shock 70 kDa protein 4 OS=Homo sapiens OX=9606 GN=HSPA4 PE=1 SV=4 4.14 2651.8 - 846626 - - - -1.9172 - 2.466 0.518 - 479.4 1 2 0 -0.0029 14 0 0 0 8.01E+06 9.53E+07 - - - 5.1311 1 221125_WJC_METTL3_EV_vs_WT_F03.13849.13849.2 1.01E-06 24-Dec R.SILSPGGSC[160.03]GPIK.V "sp|P78347|GTF2I_HUMAN,tr|A0A494C1K3|A0A494C1K3_HUMAN" 2 1271.6544 1.4 29730 13849 2 1271.653446 636.8345 General transcription factor II-I OS=Homo sapiens OX=9606 GN=GTF2I PE=1 SV=2 7.94 2652.2 - 2.42E+07 - - - -0.729 - 2.617 0.587 - 400.8 1 2 0 -0.0009 13 0 0 0 7.93E+08 5.68E+08 - - - 5.8454 0.9998 221125_WJC_METTL3_EV_vs_WT_F03.13850.13850.2 0.00486 18-Nov K.SGTYLQGTFR.A "sp|Q9Y2L1|RRP44_HUMAN,tr|F2Z2C0|F2Z2C0_HUMAN,tr|G3V1J5|G3V1J5_HUMAN" 3 1128.5564 1.48 29731 13850 2 1128.556673 565.2855 Exosome complex exonuclease RRP44 OS=Homo sapiens OX=9606 GN=DIS3 PE=1 SV=2 8.46 2652.3 - 5.58E+06 - - - 0.2658 - 1.919 0.451 - 554.4 1 2 0 0.0003 10 0 0 0 4.07E+08 2.75E+08 - - - 4.1914 0.9999 221125_WJC_METTL3_EV_vs_WT_F03.13851.13851.2 2.59E-06 16-Oct K.TEALTQAFR.R "sp|Q9Y230|RUVB2_HUMAN,tr|M0R0Y3|M0R0Y3_HUMAN,tr|M0QXI6|M0QXI6_HUMAN,tr|X6R2L4|X6R2L4_HUMAN" 4 1035.5349 0.91 29732 13851 2 1035.534651 518.7747 RuvB-like 2 OS=Homo sapiens OX=9606 GN=RUVBL2 PE=1 SV=3 5.66 2652.3 - 3.81E+06 - - - -0.2491 - 2.028 0.508 - 558 1 2 0 -0.0003 9 0 0 0 7.24E+07 7.94E+07 - - - 4.8385 0.9991 221125_WJC_METTL3_EV_vs_WT_F03.13853.13853.2 0.000859 20-Aug K.AGNFYVPAEPK[136.11].L "sp|P18124|RL7_HUMAN,tr|C9JIJ5|C9JIJ5_HUMAN,tr|C9JZ88|C9JZ88_HUMAN,tr|A8MUD9|A8MUD9_HUMAN" 4 1199.6066 1.06 29734 13853 2 1199.606846 600.8106 60S ribosomal protein L7 OS=Homo sapiens OX=9606 GN=RPL7 PE=1 SV=1 6.05 2652.5 - 1.71E+06 - - - 0.1851 - 1.729 0.268 - 218.1 1 2 0 0.0002 11 0 0 0 1.07E+08 1.01E+08 - - - 2.5016 0.9987 221125_WJC_METTL3_EV_vs_WT_F03.13855.13855.2 0.000191 20-Aug K.AGNFYVPAEPK.L "sp|P18124|RL7_HUMAN,tr|C9JIJ5|C9JIJ5_HUMAN,tr|C9JZ88|C9JZ88_HUMAN,tr|A8MUD9|A8MUD9_HUMAN" 4 1191.5924 1.07 29736 13855 2 1191.590575 596.8035 60S ribosomal protein L7 OS=Homo sapiens OX=9606 GN=RPL7 PE=1 SV=1 6.05 2652.7 - 1.14E+06 - - - -1.5517 - 1.712 0.3 - 257.2 2 2 0 -0.0018 11 0 0 0 1.06E+08 9.93E+07 - - - 2.5763 0.9986 221125_WJC_METTL3_EV_vs_WT_F03.13861.13861.3 0.982 Nov-36 R.QHLSSVVFIK.N sp|O43324|MCA3_HUMAN 1 1156.6604 0.64 29740 13861 3 1156.660392 386.5608 Eukaryotic translation elongation factor 1 epsilon-1 OS=Homo sapiens OX=9606 GN=EEF1E1 PE=1 SV=1 8.76 2653.4 - 1.05E+06 - - - -0.045 - 1.777 0.254 - 142.8 1 2 0 -0.0001 10 0 0 0 1.49E+07 2.33E+07 - - - 3.0509 0.9999 221125_WJC_METTL3_EV_vs_WT_F03.13862.13862.2 1.21E-07 18-Oct R.YSGSYNDYLR[166.11].A sp|Q96PK6|RBM14_HUMAN 1 1246.5494 1.85 29741 13862 2 1246.549019 624.282 RNA-binding protein 14 OS=Homo sapiens OX=9606 GN=RBM14 PE=1 SV=2 5.83 2653.5 - 3.35E+06 - - - -0.2952 - 1.935 0.559 - 227.9 1 2 0 -0.0004 10 0 0 0 3.16E+09 1.70E+09 - - - 5.0122 0.9984 221125_WJC_METTL3_EV_vs_WT_F03.13863.13863.2 0.079 18-Sep R.QAIPIGLQNR.D "sp|Q9BUQ8|DDX23_HUMAN,tr|H0YI52|H0YI52_HUMAN" 2 1108.6353 2.67 29742 13863 2 1108.634262 555.3249 Probable ATP-dependent RNA helicase DDX23 OS=Homo sapiens OX=9606 GN=DDX23 PE=1 SV=3 9.75 2653.6 - 1.26E+06 - - - -0.9291 - 1.761 0.199 - 290 1 2 0 -0.001 10 0 0 0 4.01E+07 1.50E+07 - - - 2.09 1 221125_WJC_METTL3_EV_vs_WT_F03.13864.13864.3 1.10E-05 13/36 K.KPVIVFVPSR.K sp|O75643|U520_HUMAN 1 1140.7019 1.6 29743 13864 3 1140.700861 381.2412 U5 small nuclear ribonucleoprotein 200 kDa helicase OS=Homo sapiens OX=9606 GN=SNRNP200 PE=1 SV=2 11 2653.7 - 974704 - - - -0.924 - 2.435 0.504 - 363 1 2 0 -0.0011 10 0 0 0 1.38E+07 8.62E+06 - - - 6.7578 0.9995 221125_WJC_METTL3_EV_vs_WT_F03.13865.13865.3 0.000251 Nov-44 K.LIPDSIGK[136.11]DIEK[136.11].A "sp|P61247|RS3A_HUMAN,tr|D6R9B6|D6R9B6_HUMAN,tr|H0Y9Y4|H0Y9Y4_HUMAN,tr|D6RB09|D6RB09_HUMAN,tr|D6RAT0|D6RAT0_HUMAN,tr|D6RG13|D6RG13_HUMAN" 6 1342.7679 1.11 29744 13865 3 1342.766787 448.5966 40S ribosomal protein S3a OS=Homo sapiens OX=9606 GN=RPS3A PE=1 SV=2 4.56 2653.9 - 716607 - - - -0.8155 - 1.987 0.414 - 132.4 1 2 1 -0.0011 12 0 0 0 1.94E+07 1.76E+07 - - - 5.0586 0.9993 221125_WJC_METTL3_EV_vs_WT_F03.13868.13868.2 0.00461 16-Jul K.IDPSALVQK.L "sp|Q9NSI2|SLX9_HUMAN,tr|C9JJU7|C9JJU7_HUMAN" 2 969.5495 1.67 29746 13868 2 969.549062 485.782 Ribosome biogenesis protein SLX9 homolog OS=Homo sapiens OX=9606 GN=SLX9 PE=1 SV=2 5.84 2654.2 - 5.69E+06 - - - -0.4476 - 1.568 0.318 - 147 1 2 0 -0.0004 9 0 0 0 8.27E+08 4.94E+08 - - - 2.6909 0.9998 221125_WJC_METTL3_EV_vs_WT_F03.13870.13870.2 7.08E-05 18-Sep K.SIYYITGESK[136.11].E "sp|Q58FF8|H90B2_HUMAN,sp|P08238|HS90B_HUMAN" 2 1167.5903 0.87 29747 13870 2 1167.59101 584.8024 Putative heat shock protein HSP 90-beta 2 OS=Homo sapiens OX=9606 GN=HSP90AB2P PE=1 SV=2 5.72 2654.4 - 2.50E+07 - - - 0.6038 - 1.747 0.457 - 228.1 1 2 0 0.0007 10 0 0 0 5.25E+08 6.03E+08 - - - 3.9734 0.9997 221125_WJC_METTL3_EV_vs_WT_F03.13871.13871.2 0.0793 14-Nov K.KLLDIVAR.S sp|Q12931|TRAP1_HUMAN 1 926.5913 2.25 29748 13871 2 926.591299 464.3029 "Heat shock protein 75 kDa, mitochondrial OS=Homo sapiens OX=9606 GN=TRAP1 PE=1 SV=3" 8.75 2654.6 - 938178 - - - -0.0032 - 2.201 0.294 - 557.1 1 2 0 0 8 0 0 0 4.66E+07 2.07E+07 - - - 3.5918 1 221125_WJC_METTL3_EV_vs_WT_F03.13874.13874.2 3.19E-07 26-Oct K.FGVEQPEGDEDLTK.E "sp|P24928|RPB1_HUMAN,tr|A0A6Q8PGB0|A0A6Q8PGB0_HUMAN" 2 1562.71 2.5 29751 13874 2 1562.707799 782.3623 DNA-directed RNA polymerase II subunit RPB1 OS=Homo sapiens OX=9606 GN=POLR2A PE=1 SV=2 3.83 2654.9 - 390928 - - - -1.4296 - 2.243 0.633 - 251.8 1 2 0 -0.0022 14 0 0 0 3.58E+06 1.43E+06 - - - 5.7428 0.9989 221125_WJC_METTL3_EV_vs_WT_F03.13877.13877.2 0.023 18-Aug K.QSLPPGLAVK.E sp|P63173|RL38_HUMAN 1 1008.5968 1.18 29753 13877 2 1008.596703 505.3057 60S ribosomal protein L38 OS=Homo sapiens OX=9606 GN=RPL38 PE=1 SV=2 8.75 2655.2 - 3.31E+07 - - - -0.0773 - 1.49 0.284 - 237.4 1 2 0 -0.0001 10 0 0 0 2.35E+09 1.98E+09 - - - 2.2517 0.9997 221125_WJC_METTL3_EV_vs_WT_F03.13879.13879.2 0.000436 16-Sep K.EYQELMNVK.L "sp|P48668|K2C6C_HUMAN,sp|P05787|K2C8_HUMAN,sp|P04259|K2C6B_HUMAN,sp|P02538|K2C6A_HUMAN,tr|Q8IWY7|Q8IWY7_HUMAN" 5 1152.5485 36.9 29754 13879 2 1152.549213 577.2815 "Keratin, type II cytoskeletal 6C OS=Homo sapiens OX=9606 GN=KRT6C PE=1 SV=3" 4.53 2655.4 - 3.11E+06 - - - 0.61 - 1.549 0.452 - 339 1 2 0 0.0007 9 0 0 0 5.04E+09 1.37E+08 - - - 3.6453 0.9898 221125_WJC_METTL3_EV_vs_WT_F03.13884.13884.3 0.00973 Oct-40 R.C[160.03]PAAMTVMHLR[166.11].K "sp|P35226|BMI1_HUMAN,tr|Q5T8Z2|Q5T8Z2_HUMAN,tr|R4GMX3|R4GMX3_HUMAN" 3 1295.6176 1.43 29759 13884 3 1295.614198 432.8798 Polycomb complex protein BMI-1 OS=Homo sapiens OX=9606 GN=BMI1 PE=1 SV=2 8.26 2656 - 523938 - - - -2.6435 - 1.631 0.226 - 123.4 1 2 0 -0.0034 11 0 0 0 1.33E+07 9.27E+06 - - - 2.4484 0.9997 221125_WJC_METTL3_EV_vs_WT_F03.13889.13889.2 0.00262 16-Aug K.AIFQTIQNR.N sp|O95373|IPO7_HUMAN 1 1089.5931 2.01 29762 13889 2 1089.593044 545.8038 Importin-7 OS=Homo sapiens OX=9606 GN=IPO7 PE=1 SV=1 9.79 2656.6 - 5.85E+06 - - - -0.045 - 1.689 0.42 - 253.7 1 2 0 0 9 0 0 0 1.46E+08 7.26E+07 - - - 3.6595 0.9727 221125_WJC_METTL3_EV_vs_WT_F03.13890.13890.2 0.882 16-Aug K.GVQTLVIGR.G "sp|Q9H7C9|AAMDC_HUMAN,tr|K4DI89|K4DI89_HUMAN,tr|E9PLK9|E9PLK9_HUMAN,tr|E9PNP3|E9PNP3_HUMAN,tr|E9PR47|E9PR47_HUMAN,tr|E9PJP1|E9PJP1_HUMAN" 6 941.5658 2.58 29763 13890 2 941.569009 471.7902 Mth938 domain-containing protein OS=Homo sapiens OX=9606 GN=AAMDC PE=1 SV=1 9.75 2656.6 - 1.79E+06 - - - 3.3922 - 1.544 0.136 - 183.3 2 2 0 0.0032 9 0 0 0 2.37E+07 9.18E+06 - - - 1.1667 0.9984 221125_WJC_METTL3_EV_vs_WT_F03.13892.13892.2 0.115 16-Aug R.EVISWGSGR[166.11].Q "sp|Q99700|ATX2_HUMAN,tr|F8W0B5|F8W0B5_HUMAN,tr|A0A5F9ZHW5|A0A5F9ZHW5_HUMAN,tr|A0A5F9ZHH4|A0A5F9ZHH4_HUMAN,tr|A0A5F9ZI57|A0A5F9ZI57_HUMAN,tr|A0A2R8YDM9|A0A2R8YDM9_HUMAN,tr|F8VQP2|F8VQP2_HUMAN,tr|A0A2R8Y5A6|A0A2R8Y5A6_HUMAN,tr|F8WB06|F8WB06_HUMAN,tr|F8VRK6|F8VRK6_HUMAN,tr|V9GY86|V9GY86_HUMAN,tr|A0A2R8Y7E6|A0A2R8Y7E6_HUMAN,tr|A0A5F9ZHX3|A0A5F9ZHX3_HUMAN,tr|H0YH87|H0YH87_HUMAN,tr|A0A2R8Y7P6|A0A2R8Y7P6_HUMAN" 15 999.5013 1.1 29765 13892 2 999.502052 500.7579 Ataxin-2 OS=Homo sapiens OX=9606 GN=ATXN2 PE=1 SV=2 6.1 2656.8 - 726564 - - - 0.7384 - 1.496 0.261 - 165.4 1 2 0 0.0007 9 0 0 0 2.17E+07 1.97E+07 - - - 2.1338 0.9999 221125_WJC_METTL3_EV_vs_WT_F03.13894.13894.2 0.000117 26-Oct K.IMAISAGDAYASNK[136.11].A sp|Q99959|PKP2_HUMAN 1 1418.6955 1.17 29767 13894 2 1418.694904 710.355 Plakophilin-2 OS=Homo sapiens OX=9606 GN=PKP2 PE=1 SV=2 5.83 2657 - 559838 - - - -0.4307 - 2.34 0.546 - 285.8 1 2 0 -0.0006 14 0 0 0 1.65E+07 1.41E+07 - - - 5.207 0.9999 221125_WJC_METTL3_EV_vs_WT_F03.13895.13895.2 1.91E-07 26-Dec K.ELSTTLNADEAVTR.G "sp|P34932|HSP74_HUMAN,tr|A0A087WTS8|A0A087WTS8_HUMAN,tr|A0A087WYC1|A0A087WYC1_HUMAN" 3 1518.7526 0.08 29768 13895 2 1518.753308 760.3836 Heat shock 70 kDa protein 4 OS=Homo sapiens OX=9606 GN=HSPA4 PE=1 SV=4 4.14 2657.2 - 550952 - - - 0.4886 - 2.508 0.566 - 476.2 1 2 0 0.0007 14 0 0 0 8.01E+06 9.53E+07 - - - 5.5286 0.9999 221125_WJC_METTL3_EV_vs_WT_F03.13896.13896.3 0.00698 13/40 K.LGIHSALLDEK[136.11].K sp|Q86SX6|GLRX5_HUMAN 1 1202.675 1.06 29769 13896 3 1202.672109 401.899 "Glutaredoxin-related protein 5, mitochondrial OS=Homo sapiens OX=9606 GN=GLRX5 PE=1 SV=2" 5.32 2657.3 - 410478 - - - -2.4354 - 2.849 0.424 - 134.8 1 2 0 -0.0029 11 0 0 0 6.83E+07 6.43E+07 - - - 6.2406 0.9989 221125_WJC_METTL3_EV_vs_WT_F03.13898.13898.2 0.00626 18-Oct K.QSLPPGLAVK[136.11].E sp|P63173|RL38_HUMAN 1 1016.611 1.18 29770 13898 2 1016.611005 509.3128 60S ribosomal protein L38 OS=Homo sapiens OX=9606 GN=RPL38 PE=1 SV=2 8.75 2657.5 - 2.37E+07 - - - 0.0236 - 1.802 0.217 - 346.3 1 2 0 0 10 0 0 0 2.35E+09 1.98E+09 - - - 2.2875 0.9975 221125_WJC_METTL3_EV_vs_WT_F03.13900.13900.2 0.0829 18-Jun K.YGIPEPPEPK.R "sp|P52756|RBM5_HUMAN,sp|P98175|RBM10_HUMAN" 2 1125.5706 11.79 29772 13900 2 1125.571255 563.7926 RNA-binding protein 5 OS=Homo sapiens OX=9606 GN=RBM5 PE=1 SV=2 4.53 2657.6 - 2.40E+06 - - - 0.5588 - 1.287 0.266 - 96.6 1 2 0 0.0006 10 0 0 0 4.39E+07 3.72E+06 - - - 1.7098 0.9999 221125_WJC_METTL3_EV_vs_WT_F03.13902.13902.2 7.85E-06 18-Oct K.EMFEDTVEER[166.11].V "sp|Q16576|RBBP7_HUMAN,tr|E9PC52|E9PC52_HUMAN" 2 1293.5423 1.42 29774 13902 2 1293.540798 647.7784 Histone-binding protein RBBP7 OS=Homo sapiens OX=9606 GN=RBBP7 PE=1 SV=1 3.91 2657.8 - 2.13E+06 - - - -1.124 - 2.053 0.593 - 370.3 1 2 0 -0.0015 10 0 0 0 1.64E+08 1.15E+08 - - - 5.4282 0.9999 221125_WJC_METTL3_EV_vs_WT_F03.13903.13903.3 1.40E-06 14/40 K.LGIHSALLDEK.K sp|Q86SX6|GLRX5_HUMAN 1 1194.6608 1.13 29775 13903 3 1194.658615 399.2276 "Glutaredoxin-related protein 5, mitochondrial OS=Homo sapiens OX=9606 GN=GLRX5 PE=1 SV=2" 5.32 2657.9 - 1.55E+06 - - - -1.8608 - 2.8 0.402 - 171.6 1 2 0 -0.0022 11 0 0 0 6.64E+07 5.86E+07 - - - 5.9463 0.9982 221125_WJC_METTL3_EV_vs_WT_F03.13904.13904.2 1.49 14-Sep K.DSLDIEVK.Q "sp|Q99961|SH3G1_HUMAN,sp|Q99962|SH3G2_HUMAN,tr|M0R0I3|M0R0I3_HUMAN,tr|M0QYE0|M0QYE0_HUMAN" 4 917.4706 1.57 29776 13904 2 917.470436 459.7426 Endophilin-A2 OS=Homo sapiens OX=9606 GN=SH3GL1 PE=1 SV=1 4.03 2658 - 1.40E+06 - - - -0.1537 - 1.747 0.155 - 286 1 2 0 -0.0001 8 0 0 0 1.69E+08 1.08E+08 - - - 1.8684 0.8543 221125_WJC_METTL3_EV_vs_WT_F03.13905.13905.3 0.418 Nov-40 K.IEVEKPFAIAK.E "sp|P23284|PPIB_HUMAN,tr|A0A7P0Z497|A0A7P0Z497_HUMAN,tr|A0A7P0TB45|A0A7P0TB45_HUMAN" 3 1243.7176 0.46 29777 13905 3 1243.720736 415.5798 Peptidyl-prolyl cis-trans isomerase B OS=Homo sapiens OX=9606 GN=PPIB PE=1 SV=2 6.14 2658.1 - 1.07E+06 - - - 2.5022 - 1.633 0.074 - 109 1 2 0 0.0031 11 0 0 0 1.00E+08 2.18E+08 - - - 0.7574 0.9998 221125_WJC_METTL3_EV_vs_WT_F03.13911.13911.2 0.00751 20-Dec K.IGSLIDVNQSK.D "sp|Q96A72|MGN2_HUMAN,sp|P61326|MGN_HUMAN,tr|F5H6P7|F5H6P7_HUMAN" 3 1172.6401 2 29781 13911 2 1172.639094 587.3273 Protein mago nashi homolog 2 OS=Homo sapiens OX=9606 GN=MAGOHB PE=1 SV=1 5.84 2658.8 - 5.90E+06 - - - -0.8596 - 2.48 0.404 - 407.8 1 2 0 -0.001 11 0 0 0 2.89E+08 1.44E+08 - - - 4.4817 0.9989 221125_WJC_METTL3_EV_vs_WT_F03.13912.13912.2 0.0529 14-Jun K.ELPEWSEK[136.11].V sp|Q8N0X7|SPART_HUMAN 1 1024.4957 1.24 29782 13912 2 1024.495384 513.2551 Spartin OS=Homo sapiens OX=9606 GN=SPART PE=1 SV=1 4.25 2658.8 - 2.55E+06 - - - -0.285 - 1.301 0.328 - 122.7 1 2 0 -0.0003 8 0 0 0 7.86E+07 6.32E+07 - - - 2.2571 0.9997 221125_WJC_METTL3_EV_vs_WT_F03.13913.13913.2 0.0193 20-Sep K.TPVPSDIDISR[166.11].S "sp|P11586|C1TC_HUMAN,tr|F5H2F4|F5H2F4_HUMAN,tr|V9GZ78|V9GZ78_HUMAN,tr|V9GYY3|V9GYY3_HUMAN,tr|A0A494C1T2|A0A494C1T2_HUMAN" 5 1208.6276 1.85 29783 13913 2 1208.628718 605.3211 "C-1-tetrahydrofolate synthase, cytoplasmic OS=Homo sapiens OX=9606 GN=MTHFD1 PE=1 SV=4" 4.21 2658.9 - 5.24E+06 - - - 0.8944 - 1.821 0.418 - 268.8 1 2 0 0.0011 11 0 0 0 3.20E+08 1.72E+08 - - - 3.7495 0.9992 221125_WJC_METTL3_EV_vs_WT_F03.13914.13914.2 0.0125 16-Sep K.AIFQTIQNR[166.11].N sp|O95373|IPO7_HUMAN 1 1099.6014 2.02 29784 13914 2 1099.601341 550.808 Importin-7 OS=Homo sapiens OX=9606 GN=IPO7 PE=1 SV=1 9.79 2658.9 - 5.09E+06 - - - -0.02 - 1.621 0.282 - 347.6 1 2 0 0 9 0 0 0 1.47E+08 7.26E+07 - - - 2.5213 0.9997 221125_WJC_METTL3_EV_vs_WT_F03.13915.13915.2 2.01E-07 18-Oct R.LVQAFQYTDK[136.11].H "sp|Q13162|PRDX4_HUMAN,tr|H7C3T4|H7C3T4_HUMAN" 2 1219.6328 0.79 29785 13915 2 1219.633602 610.8237 Peroxiredoxin-4 OS=Homo sapiens OX=9606 GN=PRDX4 PE=1 SV=1 5.83 2659 - 2.19E+06 - - - 0.6256 - 2.131 0.372 - 326.3 1 2 0 0.0008 10 0 0 0 1.96E+08 2.47E+08 - - - 3.9002 0.9948 221125_WJC_METTL3_EV_vs_WT_F03.13916.13916.2 0.561 14-Aug K.DSLDIEVK[136.11].Q "sp|Q99961|SH3G1_HUMAN,sp|Q99962|SH3G2_HUMAN,tr|M0R0I3|M0R0I3_HUMAN,tr|M0QYE0|M0QYE0_HUMAN" 4 925.4848 1.57 29786 13916 2 925.484381 463.7497 Endophilin-A2 OS=Homo sapiens OX=9606 GN=SH3GL1 PE=1 SV=1 4.03 2659 - 2.04E+06 - - - -0.4279 - 1.315 0.165 - 226.8 1 2 0 -0.0004 8 0 0 0 1.69E+08 1.08E+08 - - - 1.0854 1 221125_WJC_METTL3_EV_vs_WT_F03.13917.13917.2 4.17E-08 14/22 H.ESETTTSLVLER.S "sp|Q04837|SSBP_HUMAN,tr|C9J8J0|C9J8J0_HUMAN,tr|C9K0U8|C9K0U8_HUMAN,tr|A0A0G2JLD8|A0A0G2JLD8_HUMAN,tr|E7EUY5|E7EUY5_HUMAN" 5 1363.6831 1.46 29787 13917 2 1363.683321 682.8488 "Single-stranded DNA-binding protein, mitochondrial OS=Homo sapiens OX=9606 GN=SSBP1 PE=1 SV=1" 4.25 2659.2 - 1.96E+06 - - - 0.1694 - 2.815 0.561 - 1011.8 1 1 0 0.0002 12 0 0 0 2.07E+08 1.41E+08 - - - 5.9076 0.9998 221125_WJC_METTL3_EV_vs_WT_F03.13918.13918.2 0.000397 16-Oct K.GVQTLVIGR[166.11].G "sp|Q9H7C9|AAMDC_HUMAN,tr|K4DI89|K4DI89_HUMAN,tr|E9PLK9|E9PLK9_HUMAN,tr|E9PNP3|E9PNP3_HUMAN,tr|E9PR47|E9PR47_HUMAN,tr|E9PJP1|E9PJP1_HUMAN" 6 951.5741 2.4 29788 13918 2 951.574827 476.7943 Mth938 domain-containing protein OS=Homo sapiens OX=9606 GN=AAMDC PE=1 SV=1 9.75 2659.3 - 1.53E+06 - - - 0.7798 - 2.011 0.434 - 403.5 1 2 0 0.0007 9 0 0 0 4.16E+07 1.73E+07 - - - 4.2675 0.9963 221125_WJC_METTL3_EV_vs_WT_F03.13919.13919.3 0.299 Nov-36 R.LLLETHLPSK[136.11].K "sp|O00567|NOP56_HUMAN,tr|A0A494C128|A0A494C128_HUMAN,tr|Q5JXT2|Q5JXT2_HUMAN" 3 1157.69 1.05 29789 13919 3 1157.690972 386.9039 Nucleolar protein 56 OS=Homo sapiens OX=9606 GN=NOP56 PE=1 SV=4 6.75 2659.4 - 1.34E+06 - - - 0.8742 - 1.507 0.244 - 103.4 1 2 0 0.001 10 0 0 0 3.04E+07 2.88E+07 - - - 2.4578 0.9724 221125_WJC_METTL3_EV_vs_WT_F03.13920.13920.2 0.688 16-Aug R.LLNVEVPQK[136.11].V sp|Q9NQS7|INCE_HUMAN 1 1046.6215 1.62 29790 13920 2 1046.619677 524.318 Inner centromere protein OS=Homo sapiens OX=9606 GN=INCENP PE=1 SV=3 6 2659.4 - 1.87E+06 - - - -1.7857 - 1.047 0.159 - 167.1 1 2 0 -0.0019 9 0 0 0 3.45E+07 2.13E+07 - - - 0.3477 1 221125_WJC_METTL3_EV_vs_WT_F03.13924.13924.2 2.38E-09 14/26 R.VPVATYTNSSQPFR[166.11].L "sp|P49005|DPOD2_HUMAN,tr|A0A087WWF6|A0A087WWF6_HUMAN,tr|C9J8Z7|C9J8Z7_HUMAN,tr|F8W8R3|F8W8R3_HUMAN,tr|C9JHC7|C9JHC7_HUMAN,tr|C9IZD2|C9IZD2_HUMAN,tr|C9JLE1|C9JLE1_HUMAN" 7 1575.7921 1.16 29794 13924 2 1575.794403 788.9033 DNA polymerase delta subunit 2 OS=Homo sapiens OX=9606 GN=POLD2 PE=1 SV=1 8.72 2659.9 - 509635 - - - 1.4761 - 3.065 0.595 - 651.4 1 2 0 0.0023 14 0 0 0 9.64E+06 8.33E+06 - - - 6.2456 0.9998 221125_WJC_METTL3_EV_vs_WT_F03.13925.13925.2 0.000241 26-Dec R.VPVATYTNSSQPFR.L "sp|P49005|DPOD2_HUMAN,tr|A0A087WWF6|A0A087WWF6_HUMAN,tr|C9J8Z7|C9J8Z7_HUMAN,tr|F8W8R3|F8W8R3_HUMAN,tr|C9JHC7|C9JHC7_HUMAN,tr|C9IZD2|C9IZD2_HUMAN,tr|C9JLE1|C9JLE1_HUMAN" 7 1565.7838 1.16 29795 13925 2 1565.787365 783.8992 DNA polymerase delta subunit 2 OS=Homo sapiens OX=9606 GN=POLD2 PE=1 SV=1 8.72 2660.1 - 459176 - - - 2.2723 - 2.697 0.56 - 413.3 1 2 0 0.0036 14 0 0 0 9.64E+06 8.33E+06 - - - 5.6658 0.9997 221125_WJC_METTL3_EV_vs_WT_F03.13926.13926.2 0.0567 18-Oct R.AVLVQFSNGK.L "sp|Q9GZS1|RPA49_HUMAN,tr|E7EX70|E7EX70_HUMAN" 2 1061.5869 1.54 29796 13926 2 1061.586506 531.8007 DNA-directed RNA polymerase I subunit RPA49 OS=Homo sapiens OX=9606 GN=POLR1E PE=1 SV=3 8.8 2660.2 - 451904 - - - -0.4135 - 2.095 0.331 - 319.7 1 2 0 -0.0004 10 0 0 0 2.28E+07 1.48E+07 - - - 3.5499 0.9995 221125_WJC_METTL3_EV_vs_WT_F03.13929.13929.3 0.0548 Oct-40 K.IEVEK[136.11]PFAIAK[136.11].E "sp|P23284|PPIB_HUMAN,tr|A0A7P0Z497|A0A7P0Z497_HUMAN,tr|A0A7P0TB45|A0A7P0TB45_HUMAN" 3 1259.746 0.46 29797 13929 3 1259.744337 420.9226 Peptidyl-prolyl cis-trans isomerase B OS=Homo sapiens OX=9606 GN=PPIB PE=1 SV=2 6.14 2660.6 - 5.38E+06 - - - -1.3392 - 2.084 0.294 - 123.3 1 2 0 -0.0017 11 0 0 0 1.00E+08 2.18E+08 - - - 3.9033 0.9997 221125_WJC_METTL3_EV_vs_WT_F03.13930.13930.2 0.000986 16-Aug R.DYQELMNTK.L sp|P04264|K2C1_HUMAN 1 1140.5121 8356.31 29798 13930 2 1140.510615 571.2633 "Keratin, type II cytoskeletal 1 OS=Homo sapiens OX=9606 GN=KRT1 PE=1 SV=6" 4.37 2660.6 - 5.62E+06 - - - -1.324 - 1.561 0.493 - 193.7 1 2 0 -0.0015 9 0 0 0 1.81E+10 2.17E+06 - - - 3.9702 0.9997 221125_WJC_METTL3_EV_vs_WT_F03.13931.13931.2 0.00028 18-Aug R.AGGFASALER.H "sp|Q9Y2Q9|RT28_HUMAN,tr|E5RFT8|E5RFT8_HUMAN,tr|H7C5V3|H7C5V3_HUMAN" 3 977.493 1.45 29799 13931 2 977.492794 489.7538 "28S ribosomal protein S28, mitochondrial OS=Homo sapiens OX=9606 GN=MRPS28 PE=1 SV=1" 6.05 2660.7 - 3.04E+06 - - - -0.2558 - 1.882 0.384 - 208.2 1 2 0 -0.0003 10 0 0 0 5.41E+07 3.74E+07 - - - 3.6422 0.9995 221125_WJC_METTL3_EV_vs_WT_F03.13932.13932.2 0.00804 20-Oct K.GLLQSGQIPGR.E "sp|P09661|RU2A_HUMAN,tr|H0YMA0|H0YMA0_HUMAN,tr|H0YLR3|H0YLR3_HUMAN" 3 1124.6302 1.02 29800 13932 2 1124.630434 563.3224 U2 small nuclear ribonucleoprotein A' OS=Homo sapiens OX=9606 GN=SNRPA1 PE=1 SV=2 9.75 2660.7 - 2.92E+06 - - - 0.2027 - 1.915 0.312 - 263.2 1 2 0 0.0002 11 0 0 0 2.10E+08 2.05E+08 - - - 3.103 0.9997 221125_WJC_METTL3_EV_vs_WT_F03.13933.13933.2 0.00265 20-Oct K.GLLQSGQIPGR[166.11].E "sp|P09661|RU2A_HUMAN,tr|H0YMA0|H0YMA0_HUMAN,tr|H0YLR3|H0YLR3_HUMAN" 3 1134.6385 1.02 29801 13933 2 1134.638908 568.3265 U2 small nuclear ribonucleoprotein A' OS=Homo sapiens OX=9606 GN=SNRPA1 PE=1 SV=2 9.75 2660.8 - 2.35E+06 - - - 0.3807 - 1.934 0.388 - 272.6 1 2 0 0.0004 11 0 0 0 2.10E+08 2.05E+08 - - - 3.691 0.9998 221125_WJC_METTL3_EV_vs_WT_F03.13935.13935.3 2.87E-08 15/48 R.DMLLANKVPAAAR.A "sp|Q8NHW5|RLA0L_HUMAN,sp|P05388|RLA0_HUMAN,tr|G3V210|G3V210_HUMAN,tr|F8VU65|F8VU65_HUMAN,tr|F8VWV4|F8VWV4_HUMAN,tr|F8VWS0|F8VWS0_HUMAN,tr|F8VW21|F8VW21_HUMAN,tr|F8VRK7|F8VRK7_HUMAN,tr|F8VQY6|F8VQY6_HUMAN,tr|F8VPE8|F8VPE8_HUMAN" 10 1368.7548 1.25 29803 13935 3 1368.753551 457.2589 60S acidic ribosomal protein P0-like OS=Homo sapiens OX=9606 GN=RPLP0P6 PE=5 SV=1 8.75 2661 - 925913 - - - -0.8796 - 2.795 0.409 - 286.6 1 2 1 -0.0012 13 0 0 0 1.33E+08 1.07E+08 - - - 5.8864 0.9998 221125_WJC_METTL3_EV_vs_WT_F03.13937.13937.2 0.000152 24-Oct K.MLTAQDVSYDEAR.N sp|O15020|SPTN2_HUMAN 1 1497.677 4.54 29805 13937 2 1497.676195 749.8458 "Spectrin beta chain, non-erythrocytic 2 OS=Homo sapiens OX=9606 GN=SPTBN2 PE=1 SV=3" 4.03 2661.3 - 453012 - - - -0.5095 - 2.175 0.427 - 274.8 1 2 0 -0.0008 13 0 0 0 6.04E+06 1.33E+06 - - - 4.1888 0.9996 221125_WJC_METTL3_EV_vs_WT_F03.13941.13941.2 0.0237 16-Jul K.SC[160.03]AHDWVYE.- "sp|O60361|NDK8_HUMAN,sp|P22392|NDKB_HUMAN,tr|Q32Q12|Q32Q12_HUMAN" 3 1165.4499 - 29807 13941 2 1165.448807 583.7322 Putative nucleoside diphosphate kinase OS=Homo sapiens OX=9606 GN=NME2P1 PE=5 SV=1 4.71 2661.7 - 1.95E+07 - - - -0.9027 - 1.461 0.458 - 134.3 1 2 0 -0.0011 9 0 0 0 - - - - - 3.5203 0.9998 221125_WJC_METTL3_EV_vs_WT_F03.13942.13942.2 2.70E-05 18-Sep K.EMFEDTVEER.V "sp|Q16576|RBBP7_HUMAN,tr|E9PC52|E9PC52_HUMAN" 2 1283.534 1.42 29808 13942 2 1283.534062 642.7743 Histone-binding protein RBBP7 OS=Homo sapiens OX=9606 GN=RBBP7 PE=1 SV=1 3.91 2661.7 - 1.54E+07 - - - 0.0623 - 1.525 0.555 - 247.3 1 2 0 0.0001 10 0 0 0 1.64E+08 1.15E+08 - - - 4.3181 0.9994 221125_WJC_METTL3_EV_vs_WT_F03.13943.13943.2 0.00405 16-Jun K.FWEPDDSTK.D "sp|Q8TB72|PUM2_HUMAN,tr|C9JE24|C9JE24_HUMAN,tr|C9JW01|C9JW01_HUMAN" 3 1123.4822 2.06 29809 13943 2 1123.482343 562.7484 Pumilio homolog 2 OS=Homo sapiens OX=9606 GN=PUM2 PE=1 SV=2 4.03 2661.8 - 3.07E+06 - - - 0.1228 - 1.387 0.397 - 126.9 1 2 0 0.0001 9 0 0 0 2.37E+08 1.15E+08 - - - 2.9196 0.9998 221125_WJC_METTL3_EV_vs_WT_F03.13944.13944.2 1.65E-05 16-Aug K.NDLAVVDVR.L "sp|P19338|NUCL_HUMAN,tr|A0A7I2V506|A0A7I2V506_HUMAN,tr|A0A7I2V699|A0A7I2V699_HUMAN,tr|A0A7I2V2U7|A0A7I2V2U7_HUMAN,tr|A0A7I2V3F3|A0A7I2V3F3_HUMAN,tr|A0A7I2V428|A0A7I2V428_HUMAN,tr|A0A7I2V349|A0A7I2V349_HUMAN,tr|H7BY16|H7BY16_HUMAN,tr|A0A7I2V5M5|A0A7I2V5M5_HUMAN,tr|A0A7I2V2S8|A0A7I2V2S8_HUMAN,tr|C9JLB1|C9JLB1_HUMAN" 11 999.5349 1.33 29810 13944 2 999.534978 500.7747 Nucleolin OS=Homo sapiens OX=9606 GN=NCL PE=1 SV=3 4.21 2661.8 - 2.33E+06 - - - 0.069 - 1.934 0.461 - 242.6 1 2 0 0.0001 9 0 0 0 3.63E+08 2.73E+08 - - - 4.3542 0.9992 221125_WJC_METTL3_EV_vs_WT_F03.13947.13947.3 0.00515 Oct-40 R.LLASTLVHSVK[136.11].K "sp|Q9NYF8|BCLF1_HUMAN,tr|E9PKI6|E9PKI6_HUMAN,tr|A0A1W2PQ43|A0A1W2PQ43_HUMAN,tr|E9PK91|E9PK91_HUMAN,tr|E9PJA7|E9PJA7_HUMAN,tr|E9PK09|E9PK09_HUMAN,tr|E9PQN2|E9PQN2_HUMAN" 7 1174.7165 2.4 29812 13947 3 1174.714313 392.5794 Bcl-2-associated transcription factor 1 OS=Homo sapiens OX=9606 GN=BCLAF1 PE=1 SV=2 8.76 2662.2 - 2.66E+06 - - - -1.8694 - 1.706 0.341 - 63.5 1 2 0 -0.0022 11 0 0 0 4.05E+07 1.69E+07 - - - 3.8586 0.9997 221125_WJC_METTL3_EV_vs_WT_F03.13949.13949.2 2.94E-05 16-Aug K.FWEPDDSTK[136.11].D "sp|Q8TB72|PUM2_HUMAN,tr|C9JE24|C9JE24_HUMAN,tr|C9JW01|C9JW01_HUMAN" 3 1131.4964 2.05 29813 13949 2 1131.497621 566.7555 Pumilio homolog 2 OS=Homo sapiens OX=9606 GN=PUM2 PE=1 SV=2 4.03 2662.4 - 2.95E+06 - - - 1.0747 - 1.753 0.442 - 240.3 1 2 0 0.0012 9 0 0 0 2.37E+08 1.15E+08 - - - 3.9292 0.9742 221125_WJC_METTL3_EV_vs_WT_F03.13954.13954.2 0.576 12-May K.DIPSFER[166.11].Y "sp|P48556|PSMD8_HUMAN,tr|K7EJR3|K7EJR3_HUMAN,tr|R4GMR5|R4GMR5_HUMAN" 3 872.4268 1.2 29818 13954 2 872.424592 437.2207 26S proteasome non-ATPase regulatory subunit 8 OS=Homo sapiens OX=9606 GN=PSMD8 PE=1 SV=2 4.37 2662.7 - 1.61E+06 - - - -2.4759 - 0.985 0.234 - 98.3 1 2 0 -0.0022 7 0 0 0 6.04E+07 5.04E+07 - - - 0.7208 0.9996 221125_WJC_METTL3_EV_vs_WT_F03.13956.13956.2 0.00123 18-Nov R.IPEFDPGATK.Y "sp|Q9P2K3|RCOR3_HUMAN,tr|E9PPC5|E9PPC5_HUMAN,tr|E9PQE5|E9PQE5_HUMAN,tr|E9PR63|E9PR63_HUMAN" 4 1073.5393 2.4 29820 13956 2 1073.540658 537.7769 REST corepressor 3 OS=Homo sapiens OX=9606 GN=RCOR3 PE=1 SV=2 4.37 2663 - 1.31E+06 - - - 1.2408 - 1.962 0.371 - 351 1 2 0 0.0013 10 0 0 0 2.35E+07 9.79E+06 - - - 3.662 0.9977 221125_WJC_METTL3_EV_vs_WT_F03.13958.13958.2 0.00115 22-Nov K.NFGEEVDDESLK.E "sp|Q13310|PABP4_HUMAN,tr|A0A7I2V5W9|A0A7I2V5W9_HUMAN,tr|B1ANR0|B1ANR0_HUMAN,tr|A0A7I2V4L7|A0A7I2V4L7_HUMAN,tr|H0YCC8|H0YCC8_HUMAN,tr|A0A7I2V598|A0A7I2V598_HUMAN,tr|H0Y5F5|H0Y5F5_HUMAN" 7 1380.6045 2.61 29822 13958 2 1380.60045 691.3095 Polyadenylate-binding protein 4 OS=Homo sapiens OX=9606 GN=PABPC4 PE=1 SV=1 3.83 2663.2 - 884142 - - - -2.9371 - 1.57 0.369 - 202.7 1 2 0 -0.0041 12 0 0 0 5.18E+07 1.98E+07 - - - 2.952 0.9997 221125_WJC_METTL3_EV_vs_WT_F03.13964.13964.2 0.00628 14-Oct R.C[160.03]NNVLYIR.G sp|P62306|RUXF_HUMAN 1 1050.528 1.38 29826 13964 2 1050.529096 526.2713 Small nuclear ribonucleoprotein F OS=Homo sapiens OX=9606 GN=SNRPF PE=1 SV=1 8.22 2663.9 - 990192 - - - 0.9957 - 1.988 0.389 - 415.6 1 2 0 0.001 8 0 0 0 1.51E+08 1.10E+08 - - - 3.9862 0.9788 221125_WJC_METTL3_EV_vs_WT_F03.13965.13965.2 0.000919 16-Jul K.ESPLLNDYR.G "sp|A6ZKI3|RTL8C_HUMAN,sp|Q9BWD3|RTL8A_HUMAN" 2 1105.5404 0.54 29827 13965 2 1105.532786 553.7775 Retrotransposon Gag-like protein 8C OS=Homo sapiens OX=9606 GN=RTL8C PE=1 SV=1 4.37 2664 - 968894 - - - -6.8763 - 1.641 0.416 - 189.8 1 2 0 -0.0076 9 0 0 0 2.24E+07 4.10E+07 - - - 3.5441 0.9879 221125_WJC_METTL3_EV_vs_WT_F03.13970.13970.2 0.00455 22-Dec W.ELISNASDALDK.L "sp|Q58FF8|H90B2_HUMAN,sp|P08238|HS90B_HUMAN,sp|Q58FF6|H90B4_HUMAN,sp|Q58FF7|H90B3_HUMAN,sp|P14625|ENPL_HUMAN,tr|A0A7P0T917|A0A7P0T917_HUMAN,tr|A0A7P0Z405|A0A7P0Z405_HUMAN,tr|A0A7P0T823|A0A7P0T823_HUMAN,tr|A0A7P0TAE1|A0A7P0TAE1_HUMAN,tr|H0YIV0|H0YIV0_HUMAN,tr|A0A7P0T8R3|A0A7P0T8R3_HUMAN,tr|A0A7P0T885|A0A7P0T885_HUMAN,tr|A0A7P0TAY2|A0A7P0TAY2_HUMAN,tr|A0A087WT78|A0A087WT78_HUMAN,tr|F8W026|F8W026_HUMAN,tr|A0A7P0TBC2|A0A7P0TBC2_HUMAN,tr|A0A7P0TAT8|A0A7P0TAT8_HUMAN" 17 1274.6354 1.11 29830 13970 2 1274.633201 638.325 Putative heat shock protein HSP 90-beta 2 OS=Homo sapiens OX=9606 GN=HSP90AB2P PE=1 SV=2 4.03 2664.7 - 3.41E+07 - - - -1.7338 - 2.429 0.487 - 520.1 1 1 0 -0.0022 12 0 0 0 9.48E+08 8.54E+08 - - - 4.9724 0.9657 221125_WJC_METTL3_EV_vs_WT_F03.13972.13972.2 8.51E-05 13/22 Q.SLEASLAETEGR.Y "sp|P13645|K1C10_HUMAN,tr|A0A1B0GVI3|A0A1B0GVI3_HUMAN" 2 1261.615 3.63 29832 13972 2 1261.611657 631.8148 "Keratin, type I cytoskeletal 10 OS=Homo sapiens OX=9606 GN=KRT10 PE=1 SV=6" 4.25 2664.8 - 3.06E+06 - - - -2.6577 - 2.598 0.373 - 556.8 1 1 0 -0.0034 12 0 0 0 8.11E+07 2.24E+07 - - - 4.307 0.999 221125_WJC_METTL3_EV_vs_WT_F03.13974.13974.2 2.88E-05 18-Oct R.YYYQGC[160.03]ASWK[136.11].W sp|Q9H0D6|XRN2_HUMAN 1 1332.5689 0.5 29834 13974 2 1332.573701 667.2917 5'-3' exoribonuclease 2 OS=Homo sapiens OX=9606 GN=XRN2 PE=1 SV=1 8.15 2665 - 862448 - - - 3.6343 - 1.611 0.567 - 222.5 1 2 0 0.0048 10 0 0 0 3.74E+06 7.53E+06 - - - 4.5584 0.9991 221125_WJC_METTL3_EV_vs_WT_F03.13976.13976.3 0.013 14/40 R.LLASTLVHSVK.K "sp|Q9NYF8|BCLF1_HUMAN,tr|E9PKI6|E9PKI6_HUMAN,tr|A0A1W2PQ43|A0A1W2PQ43_HUMAN,tr|E9PK91|E9PK91_HUMAN,tr|E9PJA7|E9PJA7_HUMAN,tr|E9PK09|E9PK09_HUMAN,tr|E9PQN2|E9PQN2_HUMAN" 7 1166.7023 2.45 29835 13976 3 1166.69975 389.908 Bcl-2-associated transcription factor 1 OS=Homo sapiens OX=9606 GN=BCLAF1 PE=1 SV=2 8.76 2665.2 - 3.13E+06 - - - -2.1934 - 2.531 0.247 - 182.5 1 2 0 -0.0026 11 0 0 0 4.56E+07 1.86E+07 - - - 3.9311 0.9998 221125_WJC_METTL3_EV_vs_WT_F03.13978.13978.2 1.96E-05 14-Oct R.C[160.03]NNVLYIR[166.11].G sp|P62306|RUXF_HUMAN 1 1060.5363 1.38 29836 13978 2 1060.53766 531.2754 Small nuclear ribonucleoprotein F OS=Homo sapiens OX=9606 GN=SNRPF PE=1 SV=1 8.22 2665.4 - 1.22E+06 - - - 1.2635 - 2.302 0.487 - 431.7 1 2 0 0.0013 8 0 0 0 1.51E+08 1.10E+08 - - - 5.1522 0.9955 221125_WJC_METTL3_EV_vs_WT_F03.13981.13981.2 0.194 14-Aug R.LIFDNLKK.S "sp|P05023|AT1A1_HUMAN,sp|P13637|AT1A3_HUMAN,sp|Q13733|AT1A4_HUMAN,sp|P50993|AT1A2_HUMAN,sp|P54707|AT12A_HUMAN,sp|P20648|ATP4A_HUMAN,tr|A0A0A0MT26|A0A0A0MT26_HUMAN,tr|H0Y7C1|H0Y7C1_HUMAN,tr|A0A2R8YEY8|A0A2R8YEY8_HUMAN,tr|B1AKY9|B1AKY9_HUMAN,tr|M0R116|M0R116_HUMAN" 11 989.591 1.5 29838 13981 2 989.589267 495.8028 Sodium\potassium-transporting ATPase subunit alpha-1 OS=Homo sapiens OX=9606 GN=ATP1A1 PE=1 SV=1 8.59 2665.7 - 1.47E+06 - - - -1.7179 - 1.367 0.219 - 132.6 1 2 0 -0.0017 8 0 0 0 3.04E+07 2.02E+07 - - - 1.6008 0.9922 221125_WJC_METTL3_EV_vs_WT_F03.13984.13984.2 0.0395 14-Jul R.NC[160.03]SSFLIK[136.11].R "sp|P46779|RL28_HUMAN,tr|H0YMF4|H0YMF4_HUMAN,tr|H0YLP6|H0YLP6_HUMAN,tr|H0YKD8|H0YKD8_HUMAN" 4 975.4939 0.45 29841 13984 2 975.48986 488.7542 60S ribosomal protein L28 OS=Homo sapiens OX=9606 GN=RPL28 PE=1 SV=3 8.22 2665.9 - 1.88E+06 - - - -4.1446 - 1.453 0.332 - 183.6 1 2 0 -0.004 8 0 0 0 3.99E+07 8.88E+07 - - - 2.6187 0.9887 221125_WJC_METTL3_EV_vs_WT_F03.13988.13988.2 0.00135 16-Nov R.RGFTLVGMK.M "sp|O00746|NDKM_HUMAN,tr|Q4TT34|Q4TT34_HUMAN,tr|A0A087WVT9|A0A087WVT9_HUMAN,tr|H0Y6J0|H0Y6J0_HUMAN,tr|F2Z2X0|F2Z2X0_HUMAN" 5 1007.5586 1.64 29843 13988 2 1007.557284 504.7866 "Nucleoside diphosphate kinase, mitochondrial OS=Homo sapiens OX=9606 GN=NME4 PE=1 SV=1" 11 2666.5 - 3.03E+07 - - - -1.327 - 1.689 0.028 - 548.4 1 2 0 -0.0013 9 0 0 0 1.52E+09 9.26E+08 - - - 0.7637 0.9992 221125_WJC_METTL3_EV_vs_WT_F03.13989.13989.2 0.00227 18-Aug R.AATLAQELEK.F "sp|Q14683|SMC1A_HUMAN,tr|G8JLG1|G8JLG1_HUMAN,tr|A0A6Q8PHC3|A0A6Q8PHC3_HUMAN" 3 1072.5764 1.11 29844 13989 2 1072.578806 537.2955 Structural maintenance of chromosomes protein 1A OS=Homo sapiens OX=9606 GN=SMC1A PE=1 SV=2 4.53 2666.6 - 2.09E+06 - - - 2.2059 - 2.051 0.345 - 262.5 1 2 0 0.0024 10 0 0 0 1.74E+08 1.56E+08 - - - 3.5935 0.9999 221125_WJC_METTL3_EV_vs_WT_F03.13993.13993.2 0.00642 18-Oct K.YDESDNAFIR.A "sp|O43615|TIM44_HUMAN,tr|M0QXU7|M0QXU7_HUMAN" 2 1228.536 0.16 29846 13993 2 1228.535151 615.2753 Mitochondrial import inner membrane translocase subunit TIM44 OS=Homo sapiens OX=9606 GN=TIMM44 PE=1 SV=2 4.03 2667.1 - 3.99E+06 - - - -0.7163 - 2.014 0.559 - 325.2 1 2 0 -0.0009 10 0 0 0 1.15E+08 7.03E+08 - - - 5.1238 0.9994 221125_WJC_METTL3_EV_vs_WT_F03.13995.13995.2 0.0033 16-Oct K.NFLVEEEQR.Q sp|P19474|RO52_HUMAN 1 1162.5619 0.93 29848 13995 2 1162.559256 582.2882 E3 ubiquitin-protein ligase TRIM21 OS=Homo sapiens OX=9606 GN=TRIM21 PE=1 SV=1 4.25 2667.2 - 5.58E+06 - - - -2.233 - 1.965 0.399 - 498.3 1 2 0 -0.0026 9 0 0 0 2.50E+08 2.70E+08 - - - 3.9414 0.8918 221125_WJC_METTL3_EV_vs_WT_F03.13997.13997.2 0.000756 12-Jul R.DYSQYYR.T "sp|Q04695|K1C17_HUMAN,tr|K7EPJ9|K7EPJ9_HUMAN,tr|F5GWP8|F5GWP8_HUMAN" 3 993.4192 999 29850 13997 2 994.419696 497.7169 "Keratin, type I cytoskeletal 17 OS=Homo sapiens OX=9606 GN=KRT17 PE=1 SV=2" 5.83 2667.4 - 688949 - - - 1007.1126 - 1.277 0.429 - 200.8 1 2 0 1.0005 7 0 0 0 1.97E+07 0.00E+00 - - - 2.6702 0.9998 221125_WJC_METTL3_EV_vs_WT_F03.14000.14000.2 0.753 16-Oct K.VGLQVVAVK[136.11].A "sp|P10809|CH60_HUMAN,tr|A0A7I2V2X6|A0A7I2V2X6_HUMAN,tr|A0A7I2YQK6|A0A7I2YQK6_HUMAN,tr|A0A7I2V599|A0A7I2V599_HUMAN,tr|A0A7I2V5M1|A0A7I2V5M1_HUMAN" 5 919.5946 1.1 29851 14000 2 919.594057 460.8046 "60 kDa heat shock protein, mitochondrial OS=Homo sapiens OX=9606 GN=HSPD1 PE=1 SV=2" 8.72 2667.8 - 6.87E+06 - - - -0.5937 - 2.188 0.346 - 286.9 1 2 0 -0.0005 9 0 0 0 3.70E+08 3.35E+08 - - - 3.8616 0.9992 221125_WJC_METTL3_EV_vs_WT_F03.14001.14001.2 0.0151 16-Oct K.VGLQVVAVK.A "sp|P10809|CH60_HUMAN,tr|A0A7I2V2X6|A0A7I2V2X6_HUMAN,tr|A0A7I2YQK6|A0A7I2YQK6_HUMAN,tr|A0A7I2V599|A0A7I2V599_HUMAN,tr|A0A7I2V5M1|A0A7I2V5M1_HUMAN" 5 911.5804 1.1 29852 14001 2 911.578656 456.7975 "60 kDa heat shock protein, mitochondrial OS=Homo sapiens OX=9606 GN=HSPD1 PE=1 SV=2" 8.72 2667.9 - 6.30E+06 - - - -1.9165 - 1.989 0.297 - 284 1 2 0 -0.0017 9 0 0 0 3.70E+08 3.35E+08 - - - 3.2234 1 221125_WJC_METTL3_EV_vs_WT_F03.14003.14003.2 1.66E-08 14/22 R.EAGDVC[160.03]YADVYR.D "sp|Q07955|SRSF1_HUMAN,tr|J3KTL2|J3KTL2_HUMAN,tr|J3KSR8|J3KSR8_HUMAN" 3 1416.598 1.1 29854 14003 2 1416.595427 709.3063 Serine\arginine-rich splicing factor 1 OS=Homo sapiens OX=9606 GN=SRSF1 PE=1 SV=2 4.03 2668 - 2.74E+06 - - - -1.8022 - 2.617 0.716 - 838.4 1 2 0 -0.0026 12 0 0 0 1.30E+08 1.18E+08 - - - 6.8598 0.9977 221125_WJC_METTL3_EV_vs_WT_F03.14004.14004.2 0.482 16-Sep K.NPNAPFQIR[166.11].H sp|O94864|ST65G_HUMAN 1 1065.5595 1.83 29855 14004 2 1065.560624 533.787 STAGA complex 65 subunit gamma OS=Homo sapiens OX=9606 GN=SUPT7L PE=1 SV=1 9.75 2668.1 - 1.45E+06 - - - 1.0567 - 1.673 0.189 - 430.5 1 2 0 0.0011 9 0 0 0 1.17E+08 6.36E+07 - - - 1.9254 0.9999 221125_WJC_METTL3_EV_vs_WT_F03.14007.14007.3 1.76E-06 18/48 R.DMLLANK[136.11]VPAAAR[166.11].A "sp|Q8NHW5|RLA0L_HUMAN,sp|P05388|RLA0_HUMAN,tr|G3V210|G3V210_HUMAN,tr|F8VU65|F8VU65_HUMAN,tr|F8VWV4|F8VWV4_HUMAN,tr|F8VWS0|F8VWS0_HUMAN,tr|F8VW21|F8VW21_HUMAN,tr|F8VRK7|F8VRK7_HUMAN,tr|F8VQY6|F8VQY6_HUMAN,tr|F8VPE8|F8VPE8_HUMAN" 10 1386.7772 1.25 29856 14007 3 1386.776792 463.2664 60S acidic ribosomal protein P0-like OS=Homo sapiens OX=9606 GN=RPLP0P6 PE=5 SV=1 8.75 2668.5 - 3.38E+06 - - - -0.3122 - 2.654 0.489 - 410.7 1 2 1 -0.0004 13 0 0 0 1.33E+08 1.07E+08 - - - 6.6382 0.9945 221125_WJC_METTL3_EV_vs_WT_F03.14011.14011.2 0.0171 14-Sep K.EQIYDVYR.Y "sp|P38919|IF4A3_HUMAN,tr|I3L3H2|I3L3H2_HUMAN" 2 1084.5189 1.52 29858 14011 2 1084.514854 543.2667 Eukaryotic initiation factor 4A-III OS=Homo sapiens OX=9606 GN=EIF4A3 PE=1 SV=4 4.37 2669 - 2.57E+06 - - - -3.7537 - 1.763 0.262 - 308.8 1 2 0 -0.0041 8 0 0 0 5.15E+08 3.38E+08 - - - 2.685 1 221125_WJC_METTL3_EV_vs_WT_F03.14012.14012.2 1.15E-07 14/22 R.EAGDVC[160.03]YADVYR[166.11].D "sp|Q07955|SRSF1_HUMAN,tr|J3KTL2|J3KTL2_HUMAN,tr|J3KSR8|J3KSR8_HUMAN" 3 1426.6063 1.1 29859 14012 2 1426.606249 714.3104 Serine\arginine-rich splicing factor 1 OS=Homo sapiens OX=9606 GN=SRSF1 PE=1 SV=2 4.03 2669.1 - 4.12E+06 - - - -0.0007 - 2.632 0.625 - 830.4 1 2 0 0 12 0 0 0 1.30E+08 1.18E+08 - - - 6.2035 0.9978 221125_WJC_METTL3_EV_vs_WT_F03.14021.14021.2 0.000702 18-Sep K.LMDQLEALKK.Q "sp|Q9NP79|VTA1_HUMAN,tr|A0A087WY55|A0A087WY55_HUMAN" 2 1187.6584 1.32 29864 14021 2 1187.661165 594.8365 Vacuolar protein sorting-associated protein VTA1 homolog OS=Homo sapiens OX=9606 GN=VTA1 PE=1 SV=1 6.07 2670.2 - 783746 - - - 2.3323 - 1.826 0.254 - 195.8 1 2 0 0.0028 10 0 0 0 1.94E+07 1.47E+07 - - - 2.5969 0.9995 221125_WJC_METTL3_EV_vs_WT_F03.14022.14022.2 0.018 14-Jul K.EQIYDVYR[166.11].Y "sp|P38919|IF4A3_HUMAN,tr|I3L3H2|I3L3H2_HUMAN" 2 1094.5272 1.52 29865 14022 2 1094.527147 548.2709 Eukaryotic initiation factor 4A-III OS=Homo sapiens OX=9606 GN=EIF4A3 PE=1 SV=4 4.37 2670.3 - 3.80E+06 - - - -0.0439 - 1.564 0.366 - 266.5 1 2 0 0 8 0 0 0 5.15E+08 3.38E+08 - - - 3.0931 0.9998 221125_WJC_METTL3_EV_vs_WT_F03.14023.14023.2 7.60E-05 20-Nov K.ILEDNSIPQVK.D sp|P11177|ODPB_HUMAN 1 1254.682 1.63 29866 14023 2 1254.683038 628.3483 "Pyruvate dehydrogenase E1 component subunit beta, mitochondrial OS=Homo sapiens OX=9606 GN=PDHB PE=1 SV=3" 4.37 2670.4 - 2.06E+06 - - - 0.8536 - 2.097 0.449 - 369 1 2 0 0.0011 11 0 0 0 1.31E+08 8.02E+07 - - - 4.3602 0.9999 221125_WJC_METTL3_EV_vs_WT_F03.14026.14026.3 1.74E-05 Nov-36 K.LMDQLEALKK.Q "sp|Q9NP79|VTA1_HUMAN,tr|A0A087WY55|A0A087WY55_HUMAN" 2 1187.6584 2.06 29867 14026 3 1187.656787 396.8934 Vacuolar protein sorting-associated protein VTA1 homolog OS=Homo sapiens OX=9606 GN=VTA1 PE=1 SV=1 6.07 2670.8 - 4.56E+06 - - - -1.3539 - 2.064 0.442 - 124.6 1 2 0 -0.0016 10 0 0 0 2.23E+08 1.08E+08 - - - 5.5837 0.9915 221125_WJC_METTL3_EV_vs_WT_F03.14027.14027.2 0.154 16-Jul K.SISIGPISK.T "sp|P48449|LSS_HUMAN,tr|A0A0G2JQD0|A0A0G2JQD0_HUMAN" 2 900.528 1.19 29868 14027 2 900.525886 451.2713 Lanosterol synthase OS=Homo sapiens OX=9606 GN=LSS PE=1 SV=1 8.47 2670.9 - 440227 - - - -2.3842 - 1.32 0.221 - 116 1 2 0 -0.0021 9 0 0 0 1.72E+07 1.45E+07 - - - 1.4758 1 221125_WJC_METTL3_EV_vs_WT_F03.14029.14029.3 6.72E-05 13/40 R.VEPIHAVVLPR.G "sp|Q8N5A5|ZGPAT_HUMAN,tr|V9GY48|V9GY48_HUMAN" 2 1228.7292 1.36 29870 14029 3 1228.728167 410.5837 Zinc finger CCCH-type with G patch domain-containing protein OS=Homo sapiens OX=9606 GN=ZGPAT PE=1 SV=3 6.72 2671.1 - 1.24E+06 - - - -0.8342 - 2.36 0.444 - 229.7 1 2 0 -0.001 11 0 0 0 3.54E+07 2.60E+07 - - - 5.9292 0.9999 221125_WJC_METTL3_EV_vs_WT_F03.14030.14030.2 3.50E-06 22-Nov K.DVNVVVVEGGPK[136.11].A sp|O43395|PRPF3_HUMAN 1 1218.67 1.81 29871 14030 2 1218.670618 610.3423 U4\U6 small nuclear ribonucleoprotein Prp3 OS=Homo sapiens OX=9606 GN=PRPF3 PE=1 SV=2 4.37 2671.3 - 1.19E+06 - - - 0.5465 - 2.588 0.553 - 529.1 1 2 0 0.0007 12 0 0 0 2.57E+08 1.42E+08 - - - 5.6272 0.9994 221125_WJC_METTL3_EV_vs_WT_F03.14034.14034.2 0.0206 14/24 R.IQALAEETAQNLK.R sp|Q8IYI6|EXOC8_HUMAN 1 1427.762 2.84 29874 14034 2 1427.759436 714.8883 Exocyst complex component 8 OS=Homo sapiens OX=9606 GN=EXOC8 PE=1 SV=2 4.53 2671.6 - 5.21E+06 - - - -1.8021 - 2.032 0.351 - 686.7 1 2 0 -0.0026 13 0 0 0 1.11E+08 3.90E+07 - - - 3.4524 0.9998 221125_WJC_METTL3_EV_vs_WT_F03.14037.14037.2 0.000423 18-Nov K.SAFSEEVNIK.T "sp|Q14254|FLOT2_HUMAN,tr|E7EMK3|E7EMK3_HUMAN,tr|K7EKW9|K7EKW9_HUMAN,tr|J3QLD9|J3QLD9_HUMAN" 4 1122.5557 1.13 29875 14037 2 1122.553863 562.2851 Flotillin-2 OS=Homo sapiens OX=9606 GN=FLOT2 PE=1 SV=2 4.53 2672 - 4.53E+06 - - - -1.64 - 1.908 0.504 - 314.3 1 2 0 -0.0018 10 0 0 0 1.48E+08 1.32E+08 - - - 4.5663 0.9997 221125_WJC_METTL3_EV_vs_WT_F03.14038.14038.2 1.97E-06 18-Oct R.DGSAFEDGLR[166.11].H "sp|P55265|DSRAD_HUMAN,tr|A0A3B3IRQ9|A0A3B3IRQ9_HUMAN,tr|A0A7P0Z4K3|A0A7P0Z4K3_HUMAN,tr|A0A7P0Z4F9|A0A7P0Z4F9_HUMAN" 4 1075.481 0.62 29876 14038 2 1075.478364 538.7478 Double-stranded RNA-specific adenosine deaminase OS=Homo sapiens OX=9606 GN=ADAR PE=1 SV=4 4.03 2672 - 4.57E+06 - - - -2.4259 - 2.039 0.538 - 601.5 1 2 0 -0.0026 10 0 0 0 6.29E+07 1.01E+08 - - - 5.0025 0.9991 221125_WJC_METTL3_EV_vs_WT_F03.14039.14039.2 0.0278 12-Aug K.WNSWDPR.R sp|Q5JSZ5|PRC2B_HUMAN 1 959.425 1.74 29877 14039 2 959.424509 480.7198 Protein PRRC2B OS=Homo sapiens OX=9606 GN=PRRC2B PE=1 SV=2 5.84 2672.1 - 2.85E+06 - - - -0.4753 - 1.338 0.34 - 208.7 1 2 0 -0.0005 7 0 0 0 7.89E+07 4.54E+07 - - - 2.4747 0.9999 221125_WJC_METTL3_EV_vs_WT_F03.14042.14042.2 1.41E-07 13/22 K.DVNVVVVEGGPK.A sp|O43395|PRPF3_HUMAN 1 1210.6558 1.83 29878 14042 2 1210.656369 606.3352 U4\U6 small nuclear ribonucleoprotein Prp3 OS=Homo sapiens OX=9606 GN=PRPF3 PE=1 SV=2 4.37 2672.5 - 5.43E+06 - - - 0.5096 - 2.459 0.573 - 699.3 1 2 0 0.0006 12 0 0 0 2.57E+08 1.41E+08 - - - 5.6404 0.9759 221125_WJC_METTL3_EV_vs_WT_F03.14044.14044.2 1.90E-05 13/24 R.IQALAEETAQNLK[136.11].R sp|Q8IYI6|EXOC8_HUMAN 1 1435.7762 2.84 29879 14044 2 1436.783279 718.8954 Exocyst complex component 8 OS=Homo sapiens OX=9606 GN=EXOC8 PE=1 SV=2 4.53 2672.7 - 2.31E+06 - - - 701.4115 - 2.624 0.415 - 576.9 1 2 0 1.0071 13 0 0 0 1.11E+08 3.90E+07 - - - 4.2659 0.9942 221125_WJC_METTL3_EV_vs_WT_F03.14052.14052.3 0.0781 Dec-40 K.YVR[166.11]PFLNSISK[136.11].A "sp|O00231|PSD11_HUMAN,tr|J3QRY4|J3QRY4_HUMAN" 2 1340.7571 0.75 29883 14052 3 1340.754376 447.9263 26S proteasome non-ATPase regulatory subunit 11 OS=Homo sapiens OX=9606 GN=PSMD11 PE=1 SV=3 9.99 2673.8 - 866040 - - - -2.063 - 2.078 0.173 - 154.6 1 2 0 -0.0028 11 0 0 0 1.77E+07 2.36E+07 - - - 2.5458 0.9997 221125_WJC_METTL3_EV_vs_WT_F03.14058.14058.3 0.00227 Dec-44 K.VTVLFAGQHIAK.S "sp|P21333|FLNA_HUMAN,tr|A0A7P0NMY4|A0A7P0NMY4_HUMAN,tr|Q60FE5|Q60FE5_HUMAN,tr|A0A7I2V3E6|A0A7I2V3E6_HUMAN,tr|A0A087WWY3|A0A087WWY3_HUMAN,tr|F8WE98|F8WE98_HUMAN" 6 1282.7398 0.93 29887 14058 3 1282.739421 428.5872 Filamin-A OS=Homo sapiens OX=9606 GN=FLNA PE=1 SV=4 8.73 2674.5 - 3.50E+06 - - - -0.2619 - 2.162 0.311 - 183.9 1 2 0 -0.0003 12 0 0 0 7.28E+07 7.80E+07 - - - 4.1444 0.9996 221125_WJC_METTL3_EV_vs_WT_F03.14060.14060.2 7.40E-07 22-Dec K.C[160.03]FIVGADNVGSK.Q "sp|Q8NHW5|RLA0L_HUMAN,sp|P05388|RLA0_HUMAN,tr|G3V210|G3V210_HUMAN,tr|F8VU65|F8VU65_HUMAN,tr|F8VWV4|F8VWV4_HUMAN,tr|F8VWS0|F8VWS0_HUMAN,tr|F8VS58|F8VS58_HUMAN,tr|F8VZS0|F8VZS0_HUMAN,tr|F8VRK7|F8VRK7_HUMAN,tr|F8VQY6|F8VQY6_HUMAN,tr|F8VPE8|F8VPE8_HUMAN" 11 1265.6074 0.67 29889 14060 2 1265.603718 633.811 60S acidic ribosomal protein P0-like OS=Homo sapiens OX=9606 GN=RPLP0P6 PE=5 SV=1 5.83 2674.6 - 5.53E+06 - - - -2.9267 - 2.44 0.562 - 412.9 1 2 0 -0.0037 12 0 0 0 2.59E+08 3.88E+08 - - - 5.5378 0.9999 221125_WJC_METTL3_EV_vs_WT_F03.14064.14064.3 0.000449 13/44 K.MLSSAYISDHMK[136.11].V "sp|P56270|MAZ_HUMAN,tr|I3L0M3|I3L0M3_HUMAN,tr|H3BQI4|H3BQI4_HUMAN,tr|H3BQS2|H3BQS2_HUMAN,tr|I3L2Z5|I3L2Z5_HUMAN,tr|I3L4Y2|I3L4Y2_HUMAN,tr|A0A087WWR2|A0A087WWR2_HUMAN,tr|I3L411|I3L411_HUMAN,tr|H3BPU3|H3BPU3_HUMAN" 9 1389.6512 0.99 29891 14064 3 1389.651644 464.2243 Myc-associated zinc finger protein OS=Homo sapiens OX=9606 GN=MAZ PE=1 SV=1 6.49 2675.1 - 2.70E+06 - - - 0.3137 - 1.952 0.439 - 168.8 1 2 0 0.0004 12 0 0 0 7.70E+07 7.77E+07 - - - 5.2883 0.9984 221125_WJC_METTL3_EV_vs_WT_F03.14070.14070.2 8.54E-06 22-Dec K.C[160.03]FIVGADNVGSK[136.11].Q "sp|Q8NHW5|RLA0L_HUMAN,sp|P05388|RLA0_HUMAN,tr|G3V210|G3V210_HUMAN,tr|F8VU65|F8VU65_HUMAN,tr|F8VWV4|F8VWV4_HUMAN,tr|F8VWS0|F8VWS0_HUMAN,tr|F8VS58|F8VS58_HUMAN,tr|F8VZS0|F8VZS0_HUMAN,tr|F8VRK7|F8VRK7_HUMAN,tr|F8VQY6|F8VQY6_HUMAN,tr|F8VPE8|F8VPE8_HUMAN" 11 1273.6216 1 29895 14070 2 1273.615907 637.8181 60S acidic ribosomal protein P0-like OS=Homo sapiens OX=9606 GN=RPLP0P6 PE=5 SV=1 5.83 2675.8 - 1.15E+07 - - - -4.4872 - 2.226 0.506 - 434.9 1 2 0 -0.0057 12 0 0 0 2.55E+08 2.55E+08 - - - 4.882 0.9999 221125_WJC_METTL3_EV_vs_WT_F03.14071.14071.2 0.000111 18-Nov R.VETYLNENLR[166.11].K sp|Q9UQE7|SMC3_HUMAN 1 1259.6385 0.77 29896 14071 2 1259.637118 630.8265 Structural maintenance of chromosomes protein 3 OS=Homo sapiens OX=9606 GN=SMC3 PE=1 SV=2 4.53 2675.9 - 3.95E+06 - - - -1.1257 - 2.279 0.521 - 614.8 1 2 0 -0.0014 10 0 0 0 5.73E+07 7.46E+07 - - - 5.188 0.9997 221125_WJC_METTL3_EV_vs_WT_F03.14072.14072.3 0.000919 Sep-44 K.MLSSAYISDHMK.V "sp|P56270|MAZ_HUMAN,tr|I3L0M3|I3L0M3_HUMAN,tr|H3BQI4|H3BQI4_HUMAN,tr|H3BQS2|H3BQS2_HUMAN,tr|I3L2Z5|I3L2Z5_HUMAN,tr|I3L4Y2|I3L4Y2_HUMAN,tr|A0A087WWR2|A0A087WWR2_HUMAN,tr|I3L411|I3L411_HUMAN,tr|H3BPU3|H3BPU3_HUMAN" 9 1381.637 0.99 29897 14072 3 1381.635065 461.5529 Myc-associated zinc finger protein OS=Homo sapiens OX=9606 GN=MAZ PE=1 SV=1 6.49 2675.9 - 3.93E+06 - - - -1.4063 - 1.784 0.375 - 127 1 2 0 -0.0019 12 0 0 0 7.70E+07 7.77E+07 - - - 4.3248 0.9996 221125_WJC_METTL3_EV_vs_WT_F03.14073.14073.2 2.85E-06 22-Oct R.ENPLLPEEEEQR.A "sp|P78344|IF4G2_HUMAN,tr|H0YEC5|H0YEC5_HUMAN,tr|H0Y3P2|H0Y3P2_HUMAN,tr|H0YCH5|H0YCH5_HUMAN,tr|H0YD77|H0YD77_HUMAN,tr|D3DQV9|D3DQV9_HUMAN" 6 1481.6998 6.71 29898 14073 2 1481.701467 741.8572 Eukaryotic translation initiation factor 4 gamma 2 OS=Homo sapiens OX=9606 GN=EIF4G2 PE=1 SV=1 3.98 2676.1 - 1.34E+06 - - - 1.1237 - 2.361 0.32 - 185.6 1 2 0 0.0017 12 0 0 0 3.54E+07 5.27E+06 - - - 3.6644 0.9998 221125_WJC_METTL3_EV_vs_WT_F03.14074.14074.2 4.49E-07 26-Dec K.IIPQGADSTMLATK.T "sp|P35658|NU214_HUMAN,tr|A0A0A0MSW3|A0A0A0MSW3_HUMAN,tr|H0YF36|H0YF36_HUMAN,tr|A0A494C1F2|A0A494C1F2_HUMAN" 4 1444.7596 1.97 29899 14074 2 1444.761572 723.3871 Nuclear pore complex protein Nup214 OS=Homo sapiens OX=9606 GN=NUP214 PE=1 SV=2 5.84 2676.2 - 1.04E+06 - - - 1.3885 - 2.267 0.554 - 430.6 1 2 0 0.002 14 0 0 0 2.66E+07 1.35E+07 - - - 5.1861 0.9965 221125_WJC_METTL3_EV_vs_WT_F03.14075.14075.2 0.0239 14-Jun K.LTVEDFNR.A "sp|Q9Y6J9|TAF6L_HUMAN,tr|E9PP94|E9PP94_HUMAN" 2 992.4927 0.86 29900 14075 2 992.495023 497.2536 TAF6-like RNA polymerase II p300\CBP-associated factor-associated factor 65 kDa subunit 6L OS=Homo sapiens OX=9606 GN=TAF6L PE=1 SV=1 4.37 2676.3 - 476519 - - - 2.3305 - 1.374 0.298 - 80 1 2 0 0.0023 8 0 0 0 2.91E+07 3.37E+07 - - - 2.1995 0.9956 221125_WJC_METTL3_EV_vs_WT_F03.14076.14076.2 0.00498 24-Oct K.QLAEPASEPDVLK[136.11].L sp|Q8IWI9|MGAP_HUMAN 1 1403.7388 9.81 29901 14076 2 1403.734078 702.8767 MAX gene-associated protein OS=Homo sapiens OX=9606 GN=MGA PE=1 SV=4 4.14 2676.5 - 0 - - - -3.3354 - 1.707 0.298 - 192.9 1 2 0 -0.0047 13 0 0 0 1.50E+07 1.53E+06 - - - 2.613 0.9976 221125_WJC_METTL3_EV_vs_WT_F03.14079.14079.2 0.125 16-Aug K.TVANLLSGK[136.11].S "sp|Q13428|TCOF_HUMAN,tr|E7ETY2|E7ETY2_HUMAN,tr|H0Y8Y7|H0Y8Y7_HUMAN,tr|A0A3B3IS06|A0A3B3IS06_HUMAN,tr|A0A2R8Y857|A0A2R8Y857_HUMAN" 5 909.5375 0.98 29902 14079 2 909.536634 455.776 Treacle protein OS=Homo sapiens OX=9606 GN=TCOF1 PE=1 SV=3 8.41 2676.9 - 3.95E+06 - - - -0.9323 - 1.45 0.222 - 130.2 1 2 0 -0.0008 9 0 0 0 8.14E+07 8.34E+07 - - - 1.7554 0.9941 221125_WJC_METTL3_EV_vs_WT_F03.14080.14080.2 0.231 18-Sep R.STEPELIQVK[136.11].S "sp|Q15758|AAAT_HUMAN,tr|M0QXM4|M0QXM4_HUMAN" 2 1150.6325 1.44 29903 14080 2 1150.632997 576.3235 Neutral amino acid transporter B(0) OS=Homo sapiens OX=9606 GN=SLC1A5 PE=1 SV=2 4.53 2677 - 1.17E+06 - - - 0.4285 - 1.36 0.154 - 161.7 1 2 0 0.0005 10 0 0 0 1.53E+08 1.06E+08 - - - 1.0366 0.9803 221125_WJC_METTL3_EV_vs_WT_F03.14081.14081.2 0.00804 22-Sep R.DIIGVAETGSGK.T "sp|Q9BUQ8|DDX23_HUMAN,tr|H0YI52|H0YI52_HUMAN" 2 1145.5928 3.21 29904 14081 2 1145.599783 573.8037 Probable ATP-dependent RNA helicase DDX23 OS=Homo sapiens OX=9606 GN=DDX23 PE=1 SV=3 4.37 2677 - 1.53E+06 - - - 6.0798 - 1.644 0.365 - 138.4 1 2 0 0.007 12 0 0 0 3.64E+07 1.13E+07 - - - 3.0427 0.9995 221125_WJC_METTL3_EV_vs_WT_F03.14085.14085.2 0.00158 14-Aug K.DMVVDIQR.R sp|Q9Y266|NUDC_HUMAN 1 974.4855 1.38 29906 14085 2 974.486402 488.25 Nuclear migration protein nudC OS=Homo sapiens OX=9606 GN=NUDC PE=1 SV=1 4.21 2677.6 - 2.30E+06 - - - 0.9092 - 1.695 0.355 - 359.6 1 2 0 0.0009 8 0 0 0 1.75E+08 1.27E+08 - - - 3.2542 0.9973 221125_WJC_METTL3_EV_vs_WT_F03.14086.14086.2 0.145 16-Aug K.LK[136.11]PLEVELR[166.11].R sp|P49755|TMEDA_HUMAN 1 1113.6877 1.13 29907 14086 2 1113.688395 557.8511 Transmembrane emp24 domain-containing protein 10 OS=Homo sapiens OX=9606 GN=TMED10 PE=1 SV=2 6.14 2677.7 - 1.00E+06 - - - 0.6555 - 1.371 0.23 - 164.1 1 2 0 0.0007 9 0 0 0 3.00E+07 2.66E+07 - - - 1.6524 0.9998 221125_WJC_METTL3_EV_vs_WT_F03.14089.14089.2 1.53E-05 26-Sep K.IIPQGADSTMLATK[136.11].T "sp|P35658|NU214_HUMAN,tr|A0A0A0MSW3|A0A0A0MSW3_HUMAN,tr|H0YF36|H0YF36_HUMAN,tr|A0A494C1F2|A0A494C1F2_HUMAN" 4 1452.7738 1.97 29910 14089 2 1452.772166 727.3942 Nuclear pore complex protein Nup214 OS=Homo sapiens OX=9606 GN=NUP214 PE=1 SV=2 5.84 2678.1 - 573580 - - - -1.1013 - 2.1 0.493 - 197.2 1 2 0 -0.0016 14 0 0 0 2.66E+07 1.35E+07 - - - 4.5437 0.9999 221125_WJC_METTL3_EV_vs_WT_F03.14090.14090.3 1.15E-05 15/44 K.LSLGTYASLHGR.L "sp|Q9UHB6|LIMA1_HUMAN,tr|F8VQE1|F8VQE1_HUMAN,tr|F8VS07|F8VS07_HUMAN" 3 1273.6779 1.07 29911 14090 3 1273.677378 425.5666 LIM domain and actin-binding protein 1 OS=Homo sapiens OX=9606 GN=LIMA1 PE=1 SV=1 8.75 2678.2 - 572735 - - - -0.3981 - 2.781 0.38 - 314.9 1 2 0 -0.0005 12 0 0 0 1.08E+07 1.00E+07 - - - 5.6116 0.9995 221125_WJC_METTL3_EV_vs_WT_F03.14091.14091.2 0.0138 22-Dec K.LEAQLTENNIVK.E "sp|O15212|PFD6_HUMAN,tr|A2AB88|A2AB88_HUMAN" 2 1370.7405 3.98 29912 14091 2 1370.742776 686.3775 Prefoldin subunit 6 OS=Homo sapiens OX=9606 GN=PFDN6 PE=1 SV=1 4.53 2678.3 - 521377 - - - 1.6276 - 2.381 0.337 - 359.4 1 2 0 0.0022 12 0 0 0 2.98E+07 7.48E+06 - - - 3.812 0.9995 221125_WJC_METTL3_EV_vs_WT_F03.14094.14094.2 0.0979 22-Sep R.FLEQQNQVLETK.W "sp|Q86Y46|K2C73_HUMAN,sp|Q7RTS7|K2C74_HUMAN,sp|Q3SY84|K2C71_HUMAN,sp|Q14CN4|K2C72_HUMAN,tr|H0YIG3|H0YIG3_HUMAN,tr|F8W1S1|F8W1S1_HUMAN" 6 1475.762 999 29914 14094 2 1475.763762 738.8883 "Keratin, type II cytoskeletal 73 OS=Homo sapiens OX=9606 GN=KRT73 PE=1 SV=1" 4.53 2678.6 - 2.00E+06 - - - 1.1879 - 1.832 0.389 - 200.2 1 2 0 0.0018 12 0 0 0 1.02E+08 0.00E+00 - - - 3.5065 0.9677 221125_WJC_METTL3_EV_vs_WT_F03.14097.14097.2 0.167 20-Sep R.IIQFQATPC[160.03]PK[136.11].E "sp|Q06330|SUH_HUMAN,tr|A0A7P0Z4N7|A0A7P0Z4N7_HUMAN,tr|D6R927|D6R927_HUMAN,tr|A0A7P0T9Y9|A0A7P0T9Y9_HUMAN,tr|A0A7P0T947|A0A7P0T947_HUMAN,tr|A0A7P0TBJ4|A0A7P0TBJ4_HUMAN" 6 1309.6944 0.37 29917 14097 2 1309.698853 655.8545 Recombining binding protein suppressor of hairless OS=Homo sapiens OX=9606 GN=RBPJ PE=1 SV=3 8.22 2678.8 - 1.34E+06 - - - 3.4054 - 1.38 0.154 - 175.4 1 2 0 0.0045 11 0 0 0 8.80E+06 2.38E+07 - - - 1.0484 0.9998 221125_WJC_METTL3_EV_vs_WT_F03.14098.14098.2 0.0409 13/22 R.VQGLLEEEAAAR[166.11].G "sp|Q6SPF0|SAMD1_HUMAN,tr|E9PIW9|E9PIW9_HUMAN" 2 1294.6756 2.06 29918 14098 2 1294.675813 648.3451 Sterile alpha motif domain-containing protein 1 OS=Homo sapiens OX=9606 GN=SAMD1 PE=1 SV=1 4.25 2678.9 - 1.22E+06 - - - 0.1259 - 2.368 0.354 - 801.6 1 2 0 0.0002 12 0 0 0 6.58E+07 3.20E+07 - - - 3.9238 0.9997 221125_WJC_METTL3_EV_vs_WT_F03.14103.14103.2 0.000118 22-Nov R.ENPLLPEEEEQR[166.11].A "sp|P78344|IF4G2_HUMAN,tr|H0YEC5|H0YEC5_HUMAN,tr|H0Y3P2|H0Y3P2_HUMAN,tr|H0YCH5|H0YCH5_HUMAN,tr|H0YD77|H0YD77_HUMAN,tr|D3DQV9|D3DQV9_HUMAN" 6 1491.7081 5.95 29923 14103 2 1491.704801 746.8613 Eukaryotic translation initiation factor 4 gamma 2 OS=Homo sapiens OX=9606 GN=EIF4G2 PE=1 SV=1 3.98 2679.6 - 281717 - - - -2.1928 - 2.127 0.505 - 305.8 1 2 0 -0.0033 12 0 0 0 3.92E+07 6.59E+06 - - - 4.7557 0.9997 221125_WJC_METTL3_EV_vs_WT_F03.14105.14105.2 0.000147 14-Aug K.DMVVDIQR[166.11].R sp|Q9Y266|NUDC_HUMAN 1 984.4938 1.4 29924 14105 2 984.493822 493.2542 Nuclear migration protein nudC OS=Homo sapiens OX=9606 GN=NUDC PE=1 SV=1 4.21 2679.8 - 6.70E+06 - - - 0.0366 - 1.765 0.376 - 355.6 1 2 0 0 8 0 0 0 1.77E+08 1.27E+08 - - - 3.5316 0.9997 221125_WJC_METTL3_EV_vs_WT_F03.14107.14107.2 3.86E-05 16-Aug K.ESYSVYVYK[136.11].V "sp|Q5QNW6|H2B2F_HUMAN,sp|P58876|H2B1D_HUMAN,sp|Q99880|H2B1L_HUMAN,sp|P62807|H2B1C_HUMAN,sp|Q99877|H2B1N_HUMAN,sp|P57053|H2BFS_HUMAN,sp|O60814|H2B1K_HUMAN,sp|Q93079|H2B1H_HUMAN,sp|Q99879|H2B1M_HUMAN,tr|U3KQK0|U3KQK0_HUMAN" 10 1144.5532 1.11 29925 14107 2 1144.554742 573.2839 Histone H2B type 2-F OS=Homo sapiens OX=9606 GN=H2BC18 PE=1 SV=3 6.1 2680 - 9.60E+06 - - - 1.3551 - 1.691 0.496 - 188.3 1 2 0 0.0016 9 0 0 0 5.92E+08 5.34E+08 - - - 4.2237 0.9997 221125_WJC_METTL3_EV_vs_WT_F03.14108.14108.3 1.74E-05 13/44 K.VTVLFAGQHIAK[136.11].S "sp|P21333|FLNA_HUMAN,tr|A0A7P0NMY4|A0A7P0NMY4_HUMAN,tr|Q60FE5|Q60FE5_HUMAN,tr|A0A7I2V3E6|A0A7I2V3E6_HUMAN,tr|A0A087WWY3|A0A087WWY3_HUMAN,tr|F8WE98|F8WE98_HUMAN" 6 1290.754 0.93 29926 14108 3 1290.753787 431.2586 Filamin-A OS=Homo sapiens OX=9606 GN=FLNA PE=1 SV=4 8.73 2680 - 2.71E+06 - - - -0.1317 - 2.444 0.299 - 204.4 1 2 0 -0.0002 12 0 0 0 7.28E+07 7.80E+07 - - - 4.3505 0.9998 221125_WJC_METTL3_EV_vs_WT_F03.14109.14109.2 1.93E-05 16-Jul K.ESYSVYVYK.V "sp|Q5QNW6|H2B2F_HUMAN,sp|P58876|H2B1D_HUMAN,sp|Q99880|H2B1L_HUMAN,sp|P62807|H2B1C_HUMAN,sp|Q99877|H2B1N_HUMAN,sp|P57053|H2BFS_HUMAN,sp|O60814|H2B1K_HUMAN,sp|Q93079|H2B1H_HUMAN,sp|Q99879|H2B1M_HUMAN,tr|U3KQK0|U3KQK0_HUMAN" 10 1136.539 1.16 29927 14109 2 1136.539954 569.2768 Histone H2B type 2-F OS=Homo sapiens OX=9606 GN=H2BC18 PE=1 SV=3 6.1 2680.1 - 7.35E+06 - - - 0.8473 - 1.565 0.524 - 130.7 1 2 0 0.001 9 0 0 0 6.20E+08 5.35E+08 - - - 4.2067 0.9997 221125_WJC_METTL3_EV_vs_WT_F03.14110.14110.2 0.000561 16-Aug R.DLEQAISQR[166.11].L "sp|Q04206|TF65_HUMAN,tr|E9PKV4|E9PKV4_HUMAN,tr|A0A087WVP0|A0A087WVP0_HUMAN,tr|A0A087X0W8|A0A087X0W8_HUMAN,tr|E9PMD5|E9PMD5_HUMAN,tr|E9PQS6|E9PQS6_HUMAN,tr|E9PKH5|E9PKH5_HUMAN,tr|E9PI38|E9PI38_HUMAN,tr|Q2TAM5|Q2TAM5_HUMAN" 9 1068.5439 0.29 29928 14110 2 1068.543438 535.2792 Transcription factor p65 OS=Homo sapiens OX=9606 GN=RELA PE=1 SV=2 4.37 2680.1 - 1.75E+06 - - - -0.4389 - 1.583 0.42 - 234.9 1 2 0 -0.0005 9 0 0 0 5.81E+06 2.04E+07 - - - 3.4718 0.9999 221125_WJC_METTL3_EV_vs_WT_F03.14111.14111.2 6.75E-07 18-Dec R.SSLEVELAAK.E "sp|Q13948|CASP_HUMAN,sp|P39880|CUX1_HUMAN,tr|A0A2R8Y852|A0A2R8Y852_HUMAN,tr|A0A2R8YDI1|A0A2R8YDI1_HUMAN" 4 1045.5655 1.48 29929 14111 2 1045.5657 523.79 Protein CASP OS=Homo sapiens OX=9606 GN=CUX1 PE=1 SV=2 4.53 2680.2 - 1.63E+06 - - - 0.153 - 2.258 0.452 - 379.5 1 2 0 0.0002 10 0 0 0 7.99E+07 5.39E+07 - - - 4.6529 1 221125_WJC_METTL3_EV_vs_WT_F03.14116.14116.2 1.36E-06 14/30 A.AAYGAQPSATLAAPYR.T sp|Q96PK6|RBM14_HUMAN 1 1606.8104 2.49 29934 14116 2 1606.80912 804.4125 RNA-binding protein 14 OS=Homo sapiens OX=9606 GN=RBM14 PE=1 SV=2 8.63 2680.8 - 874127 - - - -0.7692 - 2.98 0.607 - 323.8 1 1 0 -0.0012 16 0 0 0 1.17E+07 4.71E+06 - - - 6.2085 0.9995 221125_WJC_METTL3_EV_vs_WT_F03.14119.14119.2 0.0021 13/22 K.LEAQLTENNIVK[136.11].E "sp|O15212|PFD6_HUMAN,tr|A2AB88|A2AB88_HUMAN" 2 1378.7547 3.98 29937 14119 2 1378.75757 690.3846 Prefoldin subunit 6 OS=Homo sapiens OX=9606 GN=PFDN6 PE=1 SV=1 4.53 2681.2 - 621708 - - - 2.049 - 2.345 0.381 - 494.1 1 2 0 0.0028 12 0 0 0 2.98E+07 7.48E+06 - - - 4.0967 0.9538 221125_WJC_METTL3_EV_vs_WT_F03.14121.14121.2 5.49E-05 20-Sep R.DGSFPSEPGLR.R sp|Q00587|BORG5_HUMAN 1 1160.5462 1.36 29939 14121 2 1160.540047 581.2804 Cdc42 effector protein 1 OS=Homo sapiens OX=9606 GN=CDC42EP1 PE=1 SV=1 4.37 2681.4 - 419932 - - - -5.3035 - 1.695 0.178 - 281.1 1 2 0 -0.0062 11 0 0 0 1.34E+08 9.87E+07 - - - 1.7813 0.9999 221125_WJC_METTL3_EV_vs_WT_F03.14124.14124.3 0.00133 13/36 R.SIHDALC[160.03]VIR[166.11].C "sp|P50991|TCPD_HUMAN,sp|P48643|TCPE_HUMAN,tr|E9PCA1|E9PCA1_HUMAN,tr|B7ZAR1|B7ZAR1_HUMAN,tr|E7ENZ3|E7ENZ3_HUMAN" 5 1192.6262 0.31 29940 14124 3 1192.625782 398.5493 T-complex protein 1 subunit delta OS=Homo sapiens OX=9606 GN=CCT4 PE=1 SV=4 6.46 2681.8 - 6.45E+06 - - - -0.348 - 2.131 0.449 - 326.3 1 2 0 -0.0004 10 0 0 0 1.14E+08 3.71E+08 - - - 5.7554 0.9997 221125_WJC_METTL3_EV_vs_WT_F03.14126.14126.2 0.000281 18-Oct R.SSLEVELAAK[136.11].E "sp|Q13948|CASP_HUMAN,sp|P39880|CUX1_HUMAN,tr|A0A2R8Y852|A0A2R8Y852_HUMAN,tr|A0A2R8YDI1|A0A2R8YDI1_HUMAN" 4 1053.5797 1.49 29942 14126 2 1053.581295 527.7971 Protein CASP OS=Homo sapiens OX=9606 GN=CUX1 PE=1 SV=2 4.53 2681.9 - 2.88E+06 - - - 1.4759 - 2.107 0.429 - 289.7 1 2 0 0.0016 10 0 0 0 7.72E+07 5.16E+07 - - - 4.2894 0.9997 221125_WJC_METTL3_EV_vs_WT_F03.14129.14129.2 0.018 18-Aug K.LSLTQDPVVK[136.11].V "sp|O95757|HS74L_HUMAN,tr|E9PDE8|E9PDE8_HUMAN" 2 1106.6427 0.08 29945 14129 2 1106.64325 554.3286 Heat shock 70 kDa protein 4L OS=Homo sapiens OX=9606 GN=HSPA4L PE=1 SV=3 5.84 2682.2 - 1.51E+06 - - - 0.5196 - 1.939 0.357 - 156.5 1 2 0 0.0006 10 0 0 0 8.26E+06 9.82E+07 - - - 3.5259 0.9998 221125_WJC_METTL3_EV_vs_WT_F03.14131.14131.2 0.000529 13/28 R.LEGEVTPNSLSTSYK[136.11].T "sp|Q8IWZ3|ANKH1_HUMAN,tr|A0A0A0MQZ8|A0A0A0MQZ8_HUMAN,tr|H0Y472|H0Y472_HUMAN,tr|H0Y7Y3|H0Y7Y3_HUMAN,tr|H0Y4P6|H0Y4P6_HUMAN,tr|H0Y785|H0Y785_HUMAN" 6 1631.8134 1.42 29947 14131 2 1631.815898 816.914 Ankyrin repeat and KH domain-containing protein 1 OS=Homo sapiens OX=9606 GN=ANKHD1 PE=1 SV=1 4.53 2682.4 - 517580 - - - 1.5418 - 2.599 0.515 - 499.8 1 2 0 0.0025 15 0 0 0 2.30E+07 1.62E+07 - - - 5.1922 1 221125_WJC_METTL3_EV_vs_WT_F03.14132.14132.2 1.18E-06 15/28 R.LEGEVTPNSLSTSYK.T "sp|Q8IWZ3|ANKH1_HUMAN,tr|A0A0A0MQZ8|A0A0A0MQZ8_HUMAN,tr|H0Y472|H0Y472_HUMAN,tr|H0Y7Y3|H0Y7Y3_HUMAN,tr|H0Y4P6|H0Y4P6_HUMAN,tr|H0Y785|H0Y785_HUMAN" 6 1623.7992 1.42 29948 14132 2 1623.800804 812.9069 Ankyrin repeat and KH domain-containing protein 1 OS=Homo sapiens OX=9606 GN=ANKHD1 PE=1 SV=1 4.53 2682.6 - 515854 - - - 0.9989 - 2.954 0.593 - 705.9 1 2 0 0.0016 15 0 0 0 2.30E+07 1.62E+07 - - - 6.0834 0.9994 221125_WJC_METTL3_EV_vs_WT_F03.14134.14134.2 0.00031 24-Dec R.LASNALQEPSSFR[166.11].V sp|Q9H6S0|YTDC2_HUMAN 1 1428.7237 2.69 29950 14134 2 1428.721027 715.3691 3'-5' RNA helicase YTHDC2 OS=Homo sapiens OX=9606 GN=YTHDC2 PE=1 SV=2 6 2682.8 - 474854 - - - -1.845 - 1.795 0.399 - 347.4 1 2 0 -0.0026 13 0 0 0 7.81E+06 2.91E+06 - - - 3.4886 0.9998 221125_WJC_METTL3_EV_vs_WT_F03.14135.14135.2 0.00104 24-Oct K.LLQQQNDITGLSR[166.11].Q "sp|Q9UPN9|TRI33_HUMAN,tr|H0Y612|H0Y612_HUMAN" 2 1494.803 0.29 29951 14135 2 1494.801409 748.4088 E3 ubiquitin-protein ligase TRIM33 OS=Homo sapiens OX=9606 GN=TRIM33 PE=1 SV=3 5.84 2682.9 - 449704 - - - -1.0483 - 2.301 0.391 - 329.6 1 2 0 -0.0016 13 0 0 0 1.20E+06 4.18E+06 - - - 4.0672 1 221125_WJC_METTL3_EV_vs_WT_F03.14141.14141.3 6.50E-05 13/36 R.SIHDALC[160.03]VIR.C "sp|P50991|TCPD_HUMAN,sp|P48643|TCPE_HUMAN,tr|E9PCA1|E9PCA1_HUMAN,tr|B7ZAR1|B7ZAR1_HUMAN,tr|E7ENZ3|E7ENZ3_HUMAN" 5 1182.6179 0.31 29956 14141 3 1182.617803 395.2133 T-complex protein 1 subunit delta OS=Homo sapiens OX=9606 GN=CCT4 PE=1 SV=4 6.46 2683.4 - 3.30E+06 - - - -0.1049 - 2.278 0.467 - 309 1 2 0 -0.0001 10 0 0 0 1.14E+08 3.71E+08 - - - 6.1509 0.9967 221125_WJC_METTL3_EV_vs_WT_F03.14145.14145.2 0.00122 16-Sep K.TLTPDQWAR[166.11].E "sp|Q9H3K6|BOLA2_HUMAN,tr|A0A087WZT3|A0A087WZT3_HUMAN" 2 1096.5541 0.69 29960 14145 2 1096.556429 549.2843 BolA-like protein 2 OS=Homo sapiens OX=9606 GN=BOLA2 PE=1 SV=1 5.5 2683.6 - 1.75E+06 - - - 2.144 - 1.598 0.236 - 299.7 1 2 0 0.0024 9 0 0 0 1.35E+08 1.96E+08 - - - 2.1395 0.9928 221125_WJC_METTL3_EV_vs_WT_F03.14147.14147.2 6.28E-05 13/16 Y.PDGIISK[136.11]PK[136.11].N sp|Q86U44|MTA70_HUMAN 1 969.583 0.04 29962 14147 2 969.583061 485.7988 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 9.01 2683.8 - 1.25E+06 - - - 0.0815 - 2.697 0.4 - 529.7 1 1 0 0.0001 9 0 0 0 7.06E+06 1.97E+08 - - - 4.8657 0.9995 221125_WJC_METTL3_EV_vs_WT_F03.14149.14149.2 0.00241 18-Sep K.VEVVWADNSK[136.11].T "sp|Q9C0C9|UBE2O_HUMAN,tr|K7ES11|K7ES11_HUMAN" 2 1153.5859 0.13 29964 14149 2 1153.588611 577.8002 (E3-independent) E2 ubiquitin-conjugating enzyme OS=Homo sapiens OX=9606 GN=UBE2O PE=1 SV=3 4.37 2684.1 - 736265 - - - 2.3605 - 2.12 0.43 - 315.5 1 2 0 0.0027 10 0 0 0 8.75E+05 6.61E+06 - - - 4.3136 0.8463 221125_WJC_METTL3_EV_vs_WT_F03.14151.14151.3 0.649 Sep-40 R.ELLQESALIRK.L "sp|Q12931|TRAP1_HUMAN,tr|I3L0K7|I3L0K7_HUMAN,tr|I3L239|I3L239_HUMAN" 3 1298.7558 2.97 29966 14151 3 1298.757727 433.9259 "Heat shock protein 75 kDa, mitochondrial OS=Homo sapiens OX=9606 GN=TRAP1 PE=1 SV=3" 6.24 2684.3 - 521922 - - - 1.483 - 1.554 0.052 - 106.3 1 2 0 0.0019 11 0 0 0 4.41E+06 1.48E+06 - - - 0.3715 0.9928 221125_WJC_METTL3_EV_vs_WT_F03.14153.14153.2 1.05 16-Sep R.GSDIIIVGR[166.11].G sp|P11172|UMPS_HUMAN 1 938.5425 0.35 29968 14153 2 938.544023 470.2785 Uridine 5'-monophosphate synthase OS=Homo sapiens OX=9606 GN=UMPS PE=1 SV=1 5.84 2684.6 - 511667 - - - 1.6749 - 1.45 0.161 - 225.7 1 2 0 0.0016 9 0 0 0 3.57E+06 1.01E+07 - - - 1.3046 0.9986 221125_WJC_METTL3_EV_vs_WT_F03.14160.14160.2 0.542 16-Sep K.ESTLHLVLR[166.11].L "sp|P62979|RS27A_HUMAN,sp|P0CG48|UBC_HUMAN,sp|P0CG48|UBC_HUMAN,sp|P0CG48|UBC_HUMAN,sp|P0CG48|UBC_HUMAN,sp|P0CG48|UBC_HUMAN,sp|P0CG48|UBC_HUMAN,sp|P0CG48|UBC_HUMAN,sp|P0CG48|UBC_HUMAN,sp|P0CG48|UBC_HUMAN,sp|P0CG47|UBB_HUMAN,sp|P0CG47|UBB_HUMAN,sp|P0CG47|UBB_HUMAN,sp|P62987|RL40_HUMAN,tr|F5H388|F5H388_HUMAN,tr|F5H388|F5H388_HUMAN,tr|F5GYU3|F5GYU3_HUMAN,tr|B4DV12|B4DV12_HUMAN,tr|B4DV12|B4DV12_HUMAN,tr|Q5PY61|Q5PY61_HUMAN,tr|Q5PY61|Q5PY61_HUMAN,tr|Q5PY61|Q5PY61_HUMAN,tr|F5H2Z3|F5H2Z3_HUMAN,tr|M0R2S1|M0R2S1_HUMAN,tr|J3QS39|J3QS39_HUMAN,tr|J3QTR3|J3QTR3_HUMAN,tr|Q96C32|Q96C32_HUMAN,tr|Q96C32|Q96C32_HUMAN,tr|Q96C32|Q96C32_HUMAN,tr|Q96C32|Q96C32_HUMAN,tr|F5H747|F5H747_HUMAN,tr|F5H747|F5H747_HUMAN,tr|F5GXK7|F5GXK7_HUMAN,tr|F5GXK7|F5GXK7_HUMAN,tr|M0R1M6|M0R1M6_HUMAN,tr|F5H6Q2|F5H6Q2_HUMAN,tr|J3QKN0|J3QKN0_HUMAN,tr|F5H265|F5H265_HUMAN,tr|F5H265|F5H265_HUMAN,tr|A0A2R8Y422|A0A2R8Y422_HUMAN" 40 1076.6218 0.61 29973 14160 2 1076.621956 539.3182 Ubiquitin-40S ribosomal protein S27a OS=Homo sapiens OX=9606 GN=RPS27A PE=1 SV=2 6.85 2685.3 - 4.52E+06 - - - 0.1783 - 1.47 0.266 - 361.9 1 2 0 0.0002 9 0 0 0 3.00E+08 4.94E+08 - - - 2.1202 0.9981 221125_WJC_METTL3_EV_vs_WT_F03.14162.14162.2 0.133 12-Oct R.RLQLFPR.S sp|Q5T749|KPRP_HUMAN 1 928.5607 0.59 29975 14162 2 928.561982 465.2876 Keratinocyte proline-rich protein OS=Homo sapiens OX=9606 GN=KPRP PE=1 SV=1 12 2685.5 - 2.32E+06 - - - 1.4129 - 1.816 0.179 - 250.4 1 2 0 0.0013 7 0 0 0 3.55E+07 6.04E+07 - - - 2.2532 1 221125_WJC_METTL3_EV_vs_WT_F03.14164.14164.3 0.000714 13/44 R.VVDLMAHMASK[136.11]E.- "sp|P04406|G3P_HUMAN,tr|E7EUT5|E7EUT5_HUMAN" 2 1337.6563 0.98 29977 14164 3 1337.655691 446.8927 Glyceraldehyde-3-phosphate dehydrogenase OS=Homo sapiens OX=9606 GN=GAPDH PE=1 SV=3 5.51 2685.6 - 1.95E+06 - - - -0.45 - 2.421 0.485 - 200.6 1 2 0 -0.0006 12 0 0 0 3.71E+09 3.77E+09 - - - 6.3979 0.9992 221125_WJC_METTL3_EV_vs_WT_F03.14165.14165.2 0.032 16-Jul R.NVIEAVYNR[166.11].L sp|P35813|PPM1A_HUMAN 1 1086.5697 2.95 29978 14165 2 1086.569704 544.2921 Protein phosphatase 1A OS=Homo sapiens OX=9606 GN=PPM1A PE=1 SV=1 6 2685.6 - 1.89E+06 - - - -0.0221 - 1.583 0.304 - 180.4 1 2 0 0 9 0 0 0 5.53E+07 1.87E+07 - - - 2.6152 0.9923 221125_WJC_METTL3_EV_vs_WT_F03.14167.14167.2 0.00257 14-Nov E.STLHLVLR[166.11].L "sp|P62979|RS27A_HUMAN,sp|P0CG48|UBC_HUMAN,sp|P0CG48|UBC_HUMAN,sp|P0CG48|UBC_HUMAN,sp|P0CG48|UBC_HUMAN,sp|P0CG48|UBC_HUMAN,sp|P0CG48|UBC_HUMAN,sp|P0CG48|UBC_HUMAN,sp|P0CG48|UBC_HUMAN,sp|P0CG48|UBC_HUMAN,sp|P0CG47|UBB_HUMAN,sp|P0CG47|UBB_HUMAN,sp|P0CG47|UBB_HUMAN,sp|P62987|RL40_HUMAN,tr|F5H388|F5H388_HUMAN,tr|F5H388|F5H388_HUMAN,tr|F5GYU3|F5GYU3_HUMAN,tr|B4DV12|B4DV12_HUMAN,tr|B4DV12|B4DV12_HUMAN,tr|Q5PY61|Q5PY61_HUMAN,tr|Q5PY61|Q5PY61_HUMAN,tr|Q5PY61|Q5PY61_HUMAN,tr|F5H2Z3|F5H2Z3_HUMAN,tr|M0R2S1|M0R2S1_HUMAN,tr|J3QS39|J3QS39_HUMAN,tr|J3QTR3|J3QTR3_HUMAN,tr|Q96C32|Q96C32_HUMAN,tr|Q96C32|Q96C32_HUMAN,tr|Q96C32|Q96C32_HUMAN,tr|Q96C32|Q96C32_HUMAN,tr|F5H747|F5H747_HUMAN,tr|F5H747|F5H747_HUMAN,tr|F5GXK7|F5GXK7_HUMAN,tr|F5GXK7|F5GXK7_HUMAN,tr|M0R1M6|M0R1M6_HUMAN,tr|F5H6Q2|F5H6Q2_HUMAN,tr|J3QKN0|J3QKN0_HUMAN,tr|J3QKN0|J3QKN0_HUMAN,tr|F5H265|F5H265_HUMAN,tr|F5H265|F5H265_HUMAN,tr|A0A2R8Y422|A0A2R8Y422_HUMAN" 41 947.5792 0.77 29980 14167 2 947.5787 474.7969 Ubiquitin-40S ribosomal protein S27a OS=Homo sapiens OX=9606 GN=RPS27A PE=1 SV=2 9.49 2685.8 - 1.56E+06 - - - -0.4971 - 1.986 0.496 - 537.3 1 1 0 -0.0005 8 0 0 0 1.21E+08 1.56E+08 - - - 4.7736 0.9997 221125_WJC_METTL3_EV_vs_WT_F03.14168.14168.3 0.00207 13/44 R.VVDLMAHMASKE.- "sp|P04406|G3P_HUMAN,tr|E7EUT5|E7EUT5_HUMAN" 2 1329.6421 0.98 29981 14168 3 1329.639563 444.2213 Glyceraldehyde-3-phosphate dehydrogenase OS=Homo sapiens OX=9606 GN=GAPDH PE=1 SV=3 5.51 2685.9 - 1.53E+06 - - - -1.9028 - 2.275 0.335 - 187.3 1 2 0 -0.0025 12 0 0 0 3.71E+09 3.77E+09 - - - 4.5526 0.9997 221125_WJC_METTL3_EV_vs_WT_F03.14172.14172.2 1.46E-05 20-Nov R.QQGLASYDYVR[166.11].R "sp|Q15149|PLEC_HUMAN,tr|H0YDN1|H0YDN1_HUMAN" 2 1308.6338 1.41 29985 14172 2 1308.63559 655.3242 Plectin OS=Homo sapiens OX=9606 GN=PLEC PE=1 SV=3 5.83 2686.4 - 908905 - - - 1.3793 - 1.902 0.472 - 603.3 1 2 0 0.0018 11 0 0 0 1.69E+07 1.20E+07 - - - 4.2658 0.9887 221125_WJC_METTL3_EV_vs_WT_F03.14173.14173.2 0.00136 14-Oct E.STLHLVLR.L "sp|P62979|RS27A_HUMAN,sp|P0CG48|UBC_HUMAN,sp|P0CG48|UBC_HUMAN,sp|P0CG48|UBC_HUMAN,sp|P0CG48|UBC_HUMAN,sp|P0CG48|UBC_HUMAN,sp|P0CG48|UBC_HUMAN,sp|P0CG48|UBC_HUMAN,sp|P0CG48|UBC_HUMAN,sp|P0CG48|UBC_HUMAN,sp|P0CG47|UBB_HUMAN,sp|P0CG47|UBB_HUMAN,sp|P0CG47|UBB_HUMAN,sp|P62987|RL40_HUMAN,tr|F5H388|F5H388_HUMAN,tr|F5H388|F5H388_HUMAN,tr|F5GYU3|F5GYU3_HUMAN,tr|B4DV12|B4DV12_HUMAN,tr|B4DV12|B4DV12_HUMAN,tr|Q5PY61|Q5PY61_HUMAN,tr|Q5PY61|Q5PY61_HUMAN,tr|Q5PY61|Q5PY61_HUMAN,tr|F5H2Z3|F5H2Z3_HUMAN,tr|M0R2S1|M0R2S1_HUMAN,tr|J3QS39|J3QS39_HUMAN,tr|J3QTR3|J3QTR3_HUMAN,tr|Q96C32|Q96C32_HUMAN,tr|Q96C32|Q96C32_HUMAN,tr|Q96C32|Q96C32_HUMAN,tr|Q96C32|Q96C32_HUMAN,tr|F5H747|F5H747_HUMAN,tr|F5H747|F5H747_HUMAN,tr|F5GXK7|F5GXK7_HUMAN,tr|F5GXK7|F5GXK7_HUMAN,tr|M0R1M6|M0R1M6_HUMAN,tr|F5H6Q2|F5H6Q2_HUMAN,tr|J3QKN0|J3QKN0_HUMAN,tr|J3QKN0|J3QKN0_HUMAN,tr|F5H265|F5H265_HUMAN,tr|F5H265|F5H265_HUMAN,tr|A0A2R8Y422|A0A2R8Y422_HUMAN" 41 937.5709 0.77 29986 14173 2 937.570283 469.7927 Ubiquitin-40S ribosomal protein S27a OS=Homo sapiens OX=9606 GN=RPS27A PE=1 SV=2 9.49 2686.5 - 598219 - - - -0.6592 - 1.875 0.446 - 405 1 1 0 -0.0006 8 0 0 0 1.21E+08 1.56E+08 - - - 4.2308 0.9981 221125_WJC_METTL3_EV_vs_WT_F03.14175.14175.2 0.00117 18-Aug K.QSLPPGLAVK.E sp|P63173|RL38_HUMAN 1 1008.5968 1.1 29987 14175 2 1008.59693 505.3057 60S ribosomal protein L38 OS=Homo sapiens OX=9606 GN=RPL38 PE=1 SV=2 8.75 2686.8 - 1.52E+07 - - - 0.1477 - 1.521 0.219 - 225.6 1 2 0 0.0001 10 0 0 0 5.75E+08 5.21E+08 - - - 1.8291 0.7698 221125_WJC_METTL3_EV_vs_WT_F03.14179.14179.2 3.68 12-Oct S.TLHLVLR[166.11].L "sp|P62979|RS27A_HUMAN,sp|P0CG48|UBC_HUMAN,sp|P0CG48|UBC_HUMAN,sp|P0CG48|UBC_HUMAN,sp|P0CG48|UBC_HUMAN,sp|P0CG48|UBC_HUMAN,sp|P0CG48|UBC_HUMAN,sp|P0CG48|UBC_HUMAN,sp|P0CG48|UBC_HUMAN,sp|P0CG48|UBC_HUMAN,sp|P0CG47|UBB_HUMAN,sp|P0CG47|UBB_HUMAN,sp|P0CG47|UBB_HUMAN,sp|P62987|RL40_HUMAN,tr|F5H388|F5H388_HUMAN,tr|F5H388|F5H388_HUMAN,tr|F5GYU3|F5GYU3_HUMAN,tr|B4DV12|B4DV12_HUMAN,tr|B4DV12|B4DV12_HUMAN,tr|Q5PY61|Q5PY61_HUMAN,tr|Q5PY61|Q5PY61_HUMAN,tr|Q5PY61|Q5PY61_HUMAN,tr|F5H2Z3|F5H2Z3_HUMAN,tr|M0R2S1|M0R2S1_HUMAN,tr|J3QS39|J3QS39_HUMAN,tr|J3QTR3|J3QTR3_HUMAN,tr|Q96C32|Q96C32_HUMAN,tr|Q96C32|Q96C32_HUMAN,tr|Q96C32|Q96C32_HUMAN,tr|Q96C32|Q96C32_HUMAN,tr|F5H747|F5H747_HUMAN,tr|F5H747|F5H747_HUMAN,tr|F5GXK7|F5GXK7_HUMAN,tr|F5GXK7|F5GXK7_HUMAN,tr|M0R1M6|M0R1M6_HUMAN,tr|F5H6Q2|F5H6Q2_HUMAN,tr|J3QKN0|J3QKN0_HUMAN,tr|J3QKN0|J3QKN0_HUMAN,tr|F5H265|F5H265_HUMAN,tr|F5H265|F5H265_HUMAN,tr|A0A2R8Y422|A0A2R8Y422_HUMAN" 41 860.5471 0.54 29990 14179 2 860.546959 431.2808 Ubiquitin-40S ribosomal protein S27a OS=Homo sapiens OX=9606 GN=RPS27A PE=1 SV=2 9.44 2687.1 - 2.15E+06 - - - -0.2127 - 1.534 0.096 - 473.2 1 1 0 -0.0002 7 0 0 0 4.76E+07 8.80E+07 - - - 1.1058 0.9867 221125_WJC_METTL3_EV_vs_WT_F03.14185.14185.2 0.000401 22-Nov R.YMPQNPC[160.03]IIATK.T sp|Q09028|RBBP4_HUMAN 1 1434.6999 102.1 29996 14185 2 1434.707817 718.3572 Histone-binding protein RBBP4 OS=Homo sapiens OX=9606 GN=RBBP4 PE=1 SV=3 8.2 2687.9 - 869136 - - - 5.4883 - 1.737 0.347 - 376.1 1 2 0 0.0079 12 0 0 0 6.64E+07 6.50E+05 - - - 3.0543 0.9994 221125_WJC_METTL3_EV_vs_WT_F03.14186.14186.3 0.0853 13/36 K.LQVALGELRR.K sp|P19474|RO52_HUMAN 1 1153.6931 1.01 29997 14186 3 1153.693343 385.5717 E3 ubiquitin-protein ligase TRIM21 OS=Homo sapiens OX=9606 GN=TRIM21 PE=1 SV=1 9.6 2688 - 808028 - - - 0.1751 - 2.032 0.277 - 174 1 2 0 0.0002 10 0 0 0 6.52E+06 6.49E+06 - - - 3.6989 0.9892 221125_WJC_METTL3_EV_vs_WT_F03.14187.14187.2 0.861 14-Jul K.LTVEDFNR[166.11].A "sp|Q9Y6J9|TAF6L_HUMAN,tr|E9PP94|E9PP94_HUMAN" 2 1002.501 0.82 29998 14187 2 1002.501714 502.2578 TAF6-like RNA polymerase II p300\CBP-associated factor-associated factor 65 kDa subunit 6L OS=Homo sapiens OX=9606 GN=TAF6L PE=1 SV=1 4.37 2688.1 - 710196 - - - 0.7322 - 1.271 0.124 - 124.2 1 2 0 0.0007 8 0 0 0 2.91E+07 3.53E+07 - - - 0.6799 1 221125_WJC_METTL3_EV_vs_WT_F03.14188.14188.2 1.05E-05 17/22 R.VVDLMAHMASK[136.11]E.- "sp|P04406|G3P_HUMAN,tr|E7EUT5|E7EUT5_HUMAN" 2 1337.6563 0.98 29999 14188 2 1337.652862 669.8354 Glyceraldehyde-3-phosphate dehydrogenase OS=Homo sapiens OX=9606 GN=GAPDH PE=1 SV=3 5.51 2688.3 - 531809 - - - -2.5649 - 3.088 0.584 - 832.1 1 2 0 -0.0034 12 0 0 0 6.29E+08 6.45E+08 - - - 6.3201 0.9992 221125_WJC_METTL3_EV_vs_WT_F03.14192.14192.2 0.118 18-Sep K.QSLPPGLAVK[136.11].E sp|P63173|RL38_HUMAN 1 1016.611 1.1 30002 14192 2 1016.610875 509.3128 60S ribosomal protein L38 OS=Homo sapiens OX=9606 GN=RPL38 PE=1 SV=2 8.75 2688.8 - 1.21E+07 - - - -0.1043 - 1.53 0.319 - 234.6 1 2 0 -0.0001 10 0 0 0 5.85E+08 5.30E+08 - - - 2.5842 0.9998 221125_WJC_METTL3_EV_vs_WT_F03.14197.14197.2 2.68E-05 20-Dec R.LNSSETADLLK[136.11].E "sp|P82094|TMF1_HUMAN,tr|F8WF45|F8WF45_HUMAN,tr|A0A2R8Y7M0|A0A2R8Y7M0_HUMAN" 3 1197.6332 1.86 30006 14197 2 1197.632256 599.8239 TATA element modulatory factor OS=Homo sapiens OX=9606 GN=TMF1 PE=1 SV=2 4.37 2689.2 - 6.40E+06 - - - -0.8158 - 2.52 0.385 - 421.3 1 2 0 -0.001 11 0 0 0 1.95E+08 1.05E+08 - - - 4.3846 0.9999 221125_WJC_METTL3_EV_vs_WT_F03.14198.14198.2 2.67E-06 22-Dec R.ELISNASDALEK.L sp|Q12931|TRAP1_HUMAN 1 1288.6511 2.09 30007 14198 2 1288.651186 645.3328 "Heat shock protein 75 kDa, mitochondrial OS=Homo sapiens OX=9606 GN=TRAP1 PE=1 SV=3" 4.14 2689.2 - 3.12E+06 - - - 0.097 - 2.302 0.467 - 519.5 1 2 0 0.0001 12 0 0 0 3.90E+08 1.87E+08 - - - 4.684 1 221125_WJC_METTL3_EV_vs_WT_F03.14200.14200.2 3.52E-08 17/22 R.VVDLMAHMASKE.- "sp|P04406|G3P_HUMAN,tr|E7EUT5|E7EUT5_HUMAN" 2 1329.6421 0.98 30009 14200 2 1329.638394 665.8283 Glyceraldehyde-3-phosphate dehydrogenase OS=Homo sapiens OX=9606 GN=GAPDH PE=1 SV=3 5.51 2689.5 - 1.87E+06 - - - -2.782 - 3.186 0.637 - 846.8 1 2 0 -0.0037 12 0 0 0 6.28E+08 6.45E+08 - - - 6.7936 0.962 221125_WJC_METTL3_EV_vs_WT_F03.14201.14201.2 1.89 16-Jul K.EGVDESFIK.E "sp|Q9H583|HEAT1_HUMAN,tr|Q5T3Q7|Q5T3Q7_HUMAN" 2 1022.492 0.69 30010 14201 2 1022.492443 512.2533 HEAT repeat-containing protein 1 OS=Homo sapiens OX=9606 GN=HEATR1 PE=1 SV=3 4.14 2689.5 - 1.43E+06 - - - 0.3932 - 1.115 0.057 - 141.1 1 2 0 0.0004 9 0 0 0 7.23E+07 1.05E+08 - - - -0.2232 0.9998 221125_WJC_METTL3_EV_vs_WT_F03.14202.14202.2 0.00125 24-Nov K.IQIAPDSGGLPER.S "sp|Q96AE4|FUBP1_HUMAN,tr|E9PEB5|E9PEB5_HUMAN,tr|C9JSZ1|C9JSZ1_HUMAN" 3 1351.7096 0.9 30011 14202 2 1351.708871 676.8621 Far upstream element-binding protein 1 OS=Homo sapiens OX=9606 GN=FUBP1 PE=1 SV=3 4.37 2689.7 - 1.08E+06 - - - -0.5238 - 2.332 0.391 - 324 1 2 0 -0.0007 13 0 0 0 1.08E+08 1.20E+08 - - - 4.1019 0.9859 221125_WJC_METTL3_EV_vs_WT_F03.14203.14203.2 0.0787 14-Jul R.GWAETLTK[136.11].A "sp|Q969Y2|GTPB3_HUMAN,tr|M0R0S9|M0R0S9_HUMAN" 2 912.4796 2.12 30012 14203 2 912.476812 457.2471 "tRNA modification GTPase GTPBP3, mitochondrial OS=Homo sapiens OX=9606 GN=GTPBP3 PE=1 SV=2" 6 2689.8 - 596096 - - - -3.0905 - 1.377 0.2 - 108.6 1 2 0 -0.0028 8 0 0 0 1.15E+07 5.45E+06 - - - 1.4821 0.9971 221125_WJC_METTL3_EV_vs_WT_F03.14208.14208.2 0.017 16-Aug K.TLTPDQWAR.E "sp|Q9H3K6|BOLA2_HUMAN,tr|A0A087WZT3|A0A087WZT3_HUMAN" 2 1086.5458 0.69 30015 14208 2 1086.541935 544.2802 BolA-like protein 2 OS=Homo sapiens OX=9606 GN=BOLA2 PE=1 SV=1 5.5 2690.4 - 6.15E+06 - - - -3.5645 - 1.593 0.378 - 235.6 1 2 0 -0.0039 9 0 0 0 1.35E+08 1.96E+08 - - - 3.1788 0.9971 221125_WJC_METTL3_EV_vs_WT_F03.14212.14212.2 0.0222 14-Jul R.GWAETLTK.A "sp|Q969Y2|GTPB3_HUMAN,tr|M0R0S9|M0R0S9_HUMAN" 2 904.4654 2.08 30019 14212 2 904.463684 453.24 "tRNA modification GTPase GTPBP3, mitochondrial OS=Homo sapiens OX=9606 GN=GTPBP3 PE=1 SV=2" 6 2690.7 - 802032 - - - -1.9326 - 1.394 0.275 - 177 1 2 0 -0.0017 8 0 0 0 1.15E+07 5.54E+06 - - - 2.0734 0.9918 221125_WJC_METTL3_EV_vs_WT_F03.14213.14213.2 0.000629 20-Oct R.ELAQLDQSIC[160.03]K[136.11].R sp|Q8NDZ4|DIK2A_HUMAN 1 1311.6584 2.15 30020 14213 2 1311.651478 656.8365 Divergent protein kinase domain 2A OS=Homo sapiens OX=9606 GN=DIPK2A PE=1 SV=1 4.37 2690.8 - 736309 - - - -5.2788 - 1.832 0.368 - 341.1 1 2 0 -0.0069 11 0 0 0 1.93E+07 8.98E+06 - - - 3.3946 0.9981 221125_WJC_METTL3_EV_vs_WT_F03.14218.14218.2 0.0248 14-Aug R.ETHSLFFR.S "sp|P39656|OST48_HUMAN,tr|U3KQ84|U3KQ84_HUMAN,tr|A0A0C4DGS1|A0A0C4DGS1_HUMAN" 3 1035.5138 1.37 30023 14218 2 1035.512337 518.7642 Dolichyl-diphosphooligosaccharide--protein glycosyltransferase 48 kDa subunit OS=Homo sapiens OX=9606 GN=DDOST PE=1 SV=4 6.85 2691.5 - 1.15E+06 - - - -1.3935 - 1.392 0.283 - 236.1 1 2 0 -0.0014 8 0 0 0 2.22E+07 1.62E+07 - - - 2.1283 0.9994 221125_WJC_METTL3_EV_vs_WT_F03.14219.14219.2 0.431 24-Nov R.GGIGAGLGGGLC[160.03]R.R "sp|Q9NXV2|KCTD5_HUMAN,tr|H3BSS5|H3BSS5_HUMAN" 2 1143.5819 3.79 30024 14219 2 1143.582532 572.7982 BTB\POZ domain-containing protein KCTD5 OS=Homo sapiens OX=9606 GN=KCTD5 PE=1 SV=1 8.25 2691.5 - 7.66E+06 - - - 0.5736 - 2.025 0.284 - 296 1 2 0 0.0007 13 0 0 0 5.32E+09 1.40E+09 - - - 2.9493 0.9999 221125_WJC_METTL3_EV_vs_WT_F03.14221.14221.2 1.61E-07 20-Sep R.EIMDAAEDYAK[136.11].E "sp|P14868|SYDC_HUMAN,tr|H7C278|H7C278_HUMAN" 2 1262.558 1.15 30026 14221 2 1262.556185 632.2863 "Aspartate--tRNA ligase, cytoplasmic OS=Homo sapiens OX=9606 GN=DARS1 PE=1 SV=2" 3.92 2691.7 - 1.87E+06 - - - -1.4526 - 2.099 0.607 - 238.2 1 2 0 -0.0018 11 0 0 0 5.04E+07 4.38E+07 - - - 5.5296 0.9998 221125_WJC_METTL3_EV_vs_WT_F03.14223.14223.2 8.77E-07 20-Oct K.YYTGNYDQYVK[136.11].T sp|Q9UG63|ABCF2_HUMAN 1 1420.639 0.58 30028 14223 2 1420.641096 711.3268 ATP-binding cassette sub-family F member 2 OS=Homo sapiens OX=9606 GN=ABCF2 PE=1 SV=2 5.83 2692 - 926008 - - - 1.443 - 1.929 0.513 - 166.4 1 2 0 0.002 11 0 0 0 3.15E+07 5.39E+07 - - - 4.6067 1 221125_WJC_METTL3_EV_vs_WT_F03.14230.14230.2 1.05E-08 20-Oct V.VDLMAHMASKE.- "sp|P04406|G3P_HUMAN,tr|E7EUT5|E7EUT5_HUMAN" 2 1230.5737 1.03 30033 14230 2 1230.570606 616.2941 Glyceraldehyde-3-phosphate dehydrogenase OS=Homo sapiens OX=9606 GN=GAPDH PE=1 SV=3 5.51 2692.8 - 3.77E+06 - - - -2.4972 - 2.613 0.582 - 305.4 1 1 0 -0.0031 11 0 0 0 1.88E+08 1.83E+08 - - - 5.9371 0.9997 221125_WJC_METTL3_EV_vs_WT_F03.14231.14231.2 0.307 14/18 R.YPDGIISK[136.11]PK[136.11].N sp|Q86U44|MTA70_HUMAN 1 1132.6463 0.01 30034 14231 2 1132.643999 567.3304 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 8.5 2692.9 - 4.84E+06 - - - -2.0404 - 2.084 0.489 - 748.2 1 2 0 -0.0023 10 0 0 0 1.29E+06 1.88E+08 - - - 4.7017 0.9984 221125_WJC_METTL3_EV_vs_WT_F03.14234.14234.3 4.99E-05 16/56 K.ILTGGADKNVVVFDK.S sp|Q9UMS4|PRP19_HUMAN 1 1574.8668 1.67 30037 14234 3 1574.860247 525.9629 Pre-mRNA-processing factor 19 OS=Homo sapiens OX=9606 GN=PRPF19 PE=1 SV=1 5.96 2693.1 - 1.68E+06 - - - -4.1661 - 2.834 0.443 - 342.4 1 2 1 -0.0066 15 0 0 0 4.56E+07 2.73E+07 - - - 6.1953 0.9982 221125_WJC_METTL3_EV_vs_WT_F03.14235.14235.2 0.0872 20-Sep K.ELDINNQVVPK.N "sp|Q6P4E1|GOLM2_HUMAN,tr|A0A3B3IRW9|A0A3B3IRW9_HUMAN,tr|H0YMR0|H0YMR0_HUMAN,tr|H0YM51|H0YM51_HUMAN" 4 1267.6772 0.04 30038 14235 2 1267.677274 634.8459 Protein GOLM2 OS=Homo sapiens OX=9606 GN=GOLM2 PE=1 SV=2 4.37 2693.2 - 801496 - - - 0.0458 - 1.561 0.22 - 228.5 1 2 0 0.0001 11 0 0 0 6.85E+07 1.92E+09 - - - 1.8706 0.999 221125_WJC_METTL3_EV_vs_WT_F03.14236.14236.2 0.000634 13/22 R.IEDLEEGQQVIR.S sp|Q14008|CKAP5_HUMAN 1 1427.7256 1.87 30039 14236 2 1427.71993 714.8701 Cytoskeleton-associated protein 5 OS=Homo sapiens OX=9606 GN=CKAP5 PE=1 SV=3 4 2693.4 - 707122 - - - -3.9875 - 2.632 0.476 - 873.1 1 2 0 -0.0057 12 0 0 0 1.87E+07 9.97E+06 - - - 5.1012 1 221125_WJC_METTL3_EV_vs_WT_F03.14239.14239.2 1.59E-07 16/22 K.LMTQAQLEEATR.Q "sp|P82650|RT22_HUMAN,tr|G5E9W7|G5E9W7_HUMAN,tr|A0A7P0MKV3|A0A7P0MKV3_HUMAN,tr|H7C5F2|H7C5F2_HUMAN,tr|H7C5H3|H7C5H3_HUMAN" 5 1389.6922 1.23 30040 14239 2 1389.689448 695.8534 "28S ribosomal protein S22, mitochondrial OS=Homo sapiens OX=9606 GN=MRPS22 PE=1 SV=1" 4.53 2693.8 - 3.00E+06 - - - -1.9904 - 2.882 0.556 - 1137.3 1 2 0 -0.0028 12 0 0 0 9.60E+07 7.84E+07 - - - 5.9318 0.9936 221125_WJC_METTL3_EV_vs_WT_F03.14241.14241.2 2.44E-06 14/18 V.DLMAHMASKE.- "sp|P04406|G3P_HUMAN,tr|E7EUT5|E7EUT5_HUMAN" 2 1131.5053 0.7 30042 14241 2 1131.50443 566.7599 Glyceraldehyde-3-phosphate dehydrogenase OS=Homo sapiens OX=9606 GN=GAPDH PE=1 SV=3 5.51 2693.9 - 4.78E+06 - - - -0.738 - 2.238 0.536 - 672.6 1 1 0 -0.0008 10 0 0 0 1.96E+08 2.78E+08 - - - 5.2483 1 221125_WJC_METTL3_EV_vs_WT_F03.14244.14244.2 4.45E-07 22-Oct R.MGGGSIEVSVPR.F sp|Q96I24|FUBP3_HUMAN 1 1187.5969 1.72 30043 14244 2 1187.595005 594.8057 Far upstream element-binding protein 3 OS=Homo sapiens OX=9606 GN=FUBP3 PE=1 SV=2 5.75 2694.2 - 1.21E+07 - - - -1.5595 - 2.488 0.585 - 344.6 1 2 0 -0.0019 12 0 0 0 2.04E+09 1.19E+09 - - - 5.7595 0.986 221125_WJC_METTL3_EV_vs_WT_F03.14245.14245.3 0.195 Dec-36 K.DLEIQALHAR.L "sp|Q15643|TRIPB_HUMAN,tr|H0YJ97|H0YJ97_HUMAN" 2 1164.6251 1.36 30044 14245 3 1164.619785 389.2157 Thyroid receptor-interacting protein 11 OS=Homo sapiens OX=9606 GN=TRIP11 PE=1 SV=3 5.32 2694.3 - 5.14E+06 - - - -4.5817 - 1.822 0.26 - 185.1 1 2 0 -0.0053 10 0 0 0 1.41E+08 1.04E+08 - - - 3.1893 0.994 221125_WJC_METTL3_EV_vs_WT_F03.14246.14246.2 2.87E-05 13/20 V.VDLMAHMASK[136.11]E.- "sp|P04406|G3P_HUMAN,tr|E7EUT5|E7EUT5_HUMAN" 2 1238.5879 1.03 30045 14246 2 1238.586689 620.3012 Glyceraldehyde-3-phosphate dehydrogenase OS=Homo sapiens OX=9606 GN=GAPDH PE=1 SV=3 5.51 2694.4 - 3.91E+06 - - - -0.9608 - 2.914 0.498 - 532.9 1 1 0 -0.0012 11 0 0 0 1.88E+08 1.83E+08 - - - 5.6122 0.9998 221125_WJC_METTL3_EV_vs_WT_F03.14249.14249.2 4.63E-06 16-Oct R.MEFVSEVQR.K sp|Q9BYN8|RT26_HUMAN 1 1123.5332 1.27 30046 14249 2 1123.531192 562.7739 "28S ribosomal protein S26, mitochondrial OS=Homo sapiens OX=9606 GN=MRPS26 PE=1 SV=1" 4.53 2694.8 - 2.83E+06 - - - -1.7819 - 2.272 0.505 - 568.4 1 2 0 -0.002 9 0 0 0 2.00E+08 1.57E+08 - - - 5.1445 0.9995 221125_WJC_METTL3_EV_vs_WT_F03.14250.14250.2 0.00362 16-Nov R.NATLSQVLR.E "sp|Q9NRY5|F1142_HUMAN,tr|E7ESJ7|E7ESJ7_HUMAN" 2 1000.5665 1.29 30047 14250 2 1000.564871 501.2905 Protein FAM114A2 OS=Homo sapiens OX=9606 GN=FAM114A2 PE=1 SV=4 9.75 2694.9 - 2.03E+06 - - - -1.6711 - 2.007 0.357 - 528.6 1 2 0 -0.0017 9 0 0 0 2.66E+08 2.07E+08 - - - 3.6927 0.8382 221125_WJC_METTL3_EV_vs_WT_F03.14256.14256.2 2.14E-05 24-Nov C.VVYGGADIGQQIR.D "sp|O00571|DDX3X_HUMAN,sp|O15523|DDX3Y_HUMAN,tr|A0A2R8YFR4|A0A2R8YFR4_HUMAN,tr|A0A2R8YCW1|A0A2R8YCW1_HUMAN,tr|A0A2R8YDH3|A0A2R8YDH3_HUMAN,tr|A0A2R8YDT5|A0A2R8YDT5_HUMAN,tr|A0A2R8Y645|A0A2R8Y645_HUMAN,tr|A0A2R8YF78|A0A2R8YF78_HUMAN,tr|A0A0D9SFB3|A0A0D9SFB3_HUMAN,tr|A0A2R8YFS5|A0A2R8YFS5_HUMAN,tr|A0A0D9SF53|A0A0D9SF53_HUMAN,tr|A0A2R8Y5G6|A0A2R8Y5G6_HUMAN,tr|A0A2R8Y7T2|A0A2R8Y7T2_HUMAN,tr|A0A0D9SG12|A0A0D9SG12_HUMAN,tr|F6S8Q4|F6S8Q4_HUMAN,tr|A0A2U3TZJ9|A0A2U3TZJ9_HUMAN,tr|A0A2R8Y4A4|A0A2R8Y4A4_HUMAN" 17 1374.7256 0.76 30051 14256 2 1374.718066 688.3701 ATP-dependent RNA helicase DDX3X OS=Homo sapiens OX=9606 GN=DDX3X PE=1 SV=3 5.81 2695.7 - 1.02E+06 - - - -5.4535 - 2.267 0.503 - 435.6 1 1 0 -0.0075 13 0 0 0 1.67E+07 2.20E+07 - - - 4.8544 1 221125_WJC_METTL3_EV_vs_WT_F03.14258.14258.2 8.06E-07 13/22 R.MGGGSIEVSVPR[166.11].F sp|Q96I24|FUBP3_HUMAN 1 1197.6051 1.81 30052 14258 2 1197.597888 599.8098 Far upstream element-binding protein 3 OS=Homo sapiens OX=9606 GN=FUBP3 PE=1 SV=2 5.75 2695.9 - 1.88E+07 - - - -6.0446 - 2.686 0.6 - 746.9 1 2 0 -0.0072 12 0 0 0 2.04E+09 1.13E+09 - - - 6.0701 0.8366 221125_WJC_METTL3_EV_vs_WT_F03.14259.14259.3 0.823 Sep-32 R.LAQFVEHWK.E "sp|Q13813|SPTN1_HUMAN,tr|A0A0D9SF54|A0A0D9SF54_HUMAN,tr|A0A0D9SGF6|A0A0D9SGF6_HUMAN" 3 1156.6029 0.32 30053 14259 3 1156.599648 386.5416 "Spectrin alpha chain, non-erythrocytic 1 OS=Homo sapiens OX=9606 GN=SPTAN1 PE=1 SV=3" 6.75 2696 - 1.72E+06 - - - -2.8368 - 1.487 0.095 - 83.4 1 2 0 -0.0033 9 0 0 0 4.52E+07 1.40E+08 - - - 0.794 0.9969 221125_WJC_METTL3_EV_vs_WT_F03.14260.14260.3 0.00302 Nov-40 K.FTGLSK[136.11]EELLK[136.11].V "sp|P08195|4F2_HUMAN,tr|F5H867|F5H867_HUMAN,tr|F5GZR9|F5GZR9_HUMAN,tr|A0A7P0TAN7|A0A7P0TAN7_HUMAN,tr|J3KPF3|J3KPF3_HUMAN,tr|F5H0E2|F5H0E2_HUMAN,tr|H0YH36|H0YH36_HUMAN,tr|A0A7P0TAT7|A0A7P0TAT7_HUMAN,tr|H0YFS2|H0YFS2_HUMAN,tr|A0A7P0T8U7|A0A7P0T8U7_HUMAN,tr|A0A7P0T9F7|A0A7P0T9F7_HUMAN,tr|A0A7P0TBF8|A0A7P0TBF8_HUMAN,tr|A0A7P0T8F1|A0A7P0T8F1_HUMAN,tr|A0A7P0Z4A0|A0A7P0Z4A0_HUMAN,tr|F5GZS6|F5GZS6_HUMAN,tr|A0A7P0Z4P5|A0A7P0Z4P5_HUMAN,tr|A0A7P0T853|A0A7P0T853_HUMAN,tr|A0A7P0TAS6|A0A7P0TAS6_HUMAN" 18 1279.7359 1.3 30054 14260 3 1279.732374 427.5859 4F2 cell-surface antigen heavy chain OS=Homo sapiens OX=9606 GN=SLC3A2 PE=1 SV=3 6.14 2696.1 - 1.68E+06 - - - -2.7193 - 2.003 0.356 - 106.8 1 2 1 -0.0035 11 0 0 0 3.96E+07 3.04E+07 - - - 4.4815 0.8628 221125_WJC_METTL3_EV_vs_WT_F03.14261.14261.2 0.0525 12-Jul Y.AFVHMEK[136.11].E sp|Q96PK6|RBM14_HUMAN 1 868.4357 1.47 30055 14261 2 868.435221 435.2251 RNA-binding protein 14 OS=Homo sapiens OX=9606 GN=RBM14 PE=1 SV=2 6.79 2696.3 - 810563 - - - -0.5044 - 1.344 0.219 - 188 1 1 0 -0.0004 7 0 0 0 4.07E+07 2.76E+07 - - - 1.5952 0.9998 221125_WJC_METTL3_EV_vs_WT_F03.14264.14264.3 0.00131 13/32 K.DYAFVHMEK.E sp|Q96PK6|RBM14_HUMAN 1 1138.5117 1.62 30056 14264 3 1138.509358 380.5112 RNA-binding protein 14 OS=Homo sapiens OX=9606 GN=RBM14 PE=1 SV=2 5.32 2696.6 - 1.22E+07 - - - -2.0843 - 1.835 0.45 - 263.6 1 2 0 -0.0024 9 0 0 0 3.61E+08 2.23E+08 - - - 5.3859 0.9998 221125_WJC_METTL3_EV_vs_WT_F03.14265.14265.3 0.000578 13/32 K.DYAFVHMEK[136.11].E sp|Q96PK6|RBM14_HUMAN 1 1146.5259 1.63 30057 14265 3 1146.52284 383.1826 RNA-binding protein 14 OS=Homo sapiens OX=9606 GN=RBM14 PE=1 SV=2 5.32 2696.7 - 9.43E+06 - - - -2.696 - 1.764 0.477 - 270.2 1 2 0 -0.0031 9 0 0 0 3.63E+08 2.23E+08 - - - 5.5678 0.9986 221125_WJC_METTL3_EV_vs_WT_F03.14272.14272.2 0.0786 18-Oct K.QLVTNAC[160.03]LIK.E "sp|Q99873|ANM1_HUMAN,tr|E9PKG1|E9PKG1_HUMAN,tr|E9PIX6|E9PIX6_HUMAN" 3 1158.6431 2.69 30062 14272 2 1158.640926 580.3288 Protein arginine N-methyltransferase 1 OS=Homo sapiens OX=9606 GN=PRMT1 PE=1 SV=3 8.22 2697.5 - 5.29E+06 - - - -1.8591 - 1.824 0.267 - 328.9 1 2 0 -0.0022 10 0 0 0 1.88E+08 6.99E+07 - - - 2.69 0.9999 221125_WJC_METTL3_EV_vs_WT_F03.14276.14276.2 2.10E-06 24-Nov K.LGEMWNNTAADDK[136.11].Q "sp|B2RPK0|HGB1A_HUMAN,sp|P09429|HMGB1_HUMAN,tr|Q5T7C4|Q5T7C4_HUMAN" 3 1471.6493 0.08 30066 14276 2 1471.650428 736.8319 Putative high mobility group protein B1-like 1 OS=Homo sapiens OX=9606 GN=HMGB1P1 PE=5 SV=1 4.03 2697.9 - 1.03E+06 - - - 0.7712 - 2.408 0.52 - 444.8 1 2 0 0.0011 13 0 0 0 1.34E+06 1.73E+07 - - - 5.1368 0.9998 221125_WJC_METTL3_EV_vs_WT_F03.14279.14279.2 7.69E-06 13/22 K.LMTQAQLEEATR[166.11].Q "sp|P82650|RT22_HUMAN,tr|G5E9W7|G5E9W7_HUMAN,tr|A0A7P0MKV3|A0A7P0MKV3_HUMAN,tr|H7C5F2|H7C5F2_HUMAN,tr|H7C5H3|H7C5H3_HUMAN" 5 1399.7005 1.23 30067 14279 2 1399.698582 700.8575 "28S ribosomal protein S22, mitochondrial OS=Homo sapiens OX=9606 GN=MRPS22 PE=1 SV=1" 4.53 2698.3 - 2.34E+06 - - - -1.3589 - 2.64 0.476 - 724.9 1 2 0 -0.0019 12 0 0 0 9.60E+07 7.84E+07 - - - 5.1104 0.8013 221125_WJC_METTL3_EV_vs_WT_F03.14281.14281.2 0.288 12-Jun Y.AFVHMEK.E sp|Q96PK6|RBM14_HUMAN 1 860.4215 1.46 30069 14281 2 860.42059 431.218 RNA-binding protein 14 OS=Homo sapiens OX=9606 GN=RBM14 PE=1 SV=2 6.79 2698.6 - 2.47E+06 - - - -1.01 - 1.247 0.222 - 159.7 1 1 0 -0.0009 7 0 0 0 4.10E+07 2.81E+07 - - - 1.3798 0.9999 221125_WJC_METTL3_EV_vs_WT_F03.14282.14282.2 1.52E-07 18-Nov R.AYEYVEC[160.03]PIR[166.11].G sp|P53701|CCHL_HUMAN 1 1308.6048 1.35 30070 14282 2 1308.603661 655.3097 Holocytochrome c-type synthase OS=Homo sapiens OX=9606 GN=HCCS PE=1 SV=1 4.53 2698.7 - 823997 - - - -0.865 - 2.386 0.567 - 551.7 1 2 0 -0.0011 10 0 0 0 2.29E+07 1.70E+07 - - - 5.6559 0.9536 221125_WJC_METTL3_EV_vs_WT_F03.14285.14285.2 0.0176 26-Dec Y.ASAVGIGTTQVQPE.- "sp|Q16891|MIC60_HUMAN,tr|B9A067|B9A067_HUMAN,tr|A0A087WYS0|A0A087WYS0_HUMAN,tr|C9J406|C9J406_HUMAN,tr|H7C463|H7C463_HUMAN" 5 1356.6885 - 30071 14285 2 1356.686093 679.3515 MICOS complex subunit MIC60 OS=Homo sapiens OX=9606 GN=IMMT PE=1 SV=1 4.6 2699.1 - 2.76E+06 - - - -1.7808 - 2.046 0.315 - 234.7 1 1 0 -0.0024 14 0 0 0 - - - - - 3.1633 0.9999 221125_WJC_METTL3_EV_vs_WT_F03.14286.14286.3 0.0941 17/36 K.LNLVVKPLEK.V "sp|P11441|UBL4A_HUMAN,tr|Q5HY81|Q5HY81_HUMAN" 2 1151.7278 1.64 30072 14286 3 1151.725395 384.9165 Ubiquitin-like protein 4A OS=Homo sapiens OX=9606 GN=UBL4A PE=1 SV=1 8.59 2699.2 - 2.66E+06 - - - -2.0838 - 2.613 0.377 - 342 1 2 0 -0.0024 10 0 0 0 1.23E+08 7.52E+07 - - - 5.5476 0.9988 221125_WJC_METTL3_EV_vs_WT_F03.14287.14287.2 1.43 16-Sep R.SGVSLAALK[136.11].K "sp|P10412|H14_HUMAN,sp|P16403|H12_HUMAN,sp|P16402|H13_HUMAN" 3 852.516 0.74 30073 14287 2 852.514492 427.2653 Histone H1.4 OS=Homo sapiens OX=9606 GN=H1-4 PE=1 SV=2 8.47 2699.3 - 7.03E+06 - - - -1.79 - 2.054 0.224 - 246.1 1 2 0 -0.0015 9 0 0 0 1.97E+08 2.68E+08 - - - 2.7774 0.998 221125_WJC_METTL3_EV_vs_WT_F03.14289.14289.2 3.78E-05 20-Oct K.GQLPEAPVIGK[136.11].Q "sp|P55265|DSRAD_HUMAN,tr|A2IBT1|A2IBT1_HUMAN,tr|A0A3B3IRQ9|A0A3B3IRQ9_HUMAN,tr|A0A3B3ISU1|A0A3B3ISU1_HUMAN,tr|A0A7P0Z4K3|A0A7P0Z4K3_HUMAN,tr|A0A3B3ISX1|A0A3B3ISX1_HUMAN" 6 1115.643 0.99 30075 14289 2 1115.639177 558.8288 Double-stranded RNA-specific adenosine deaminase OS=Homo sapiens OX=9606 GN=ADAR PE=1 SV=4 6 2699.5 - 2.17E+06 - - - -3.4348 - 2.112 0.326 - 299 1 2 0 -0.0038 11 0 0 0 6.96E+07 7.04E+07 - - - 3.4702 0.998 221125_WJC_METTL3_EV_vs_WT_F03.14290.14290.2 0.0413 20-Oct K.GQLPEAPVIGK.Q "sp|P55265|DSRAD_HUMAN,tr|A2IBT1|A2IBT1_HUMAN,tr|A0A3B3IRQ9|A0A3B3IRQ9_HUMAN,tr|A0A3B3ISU1|A0A3B3ISU1_HUMAN,tr|A0A7P0Z4K3|A0A7P0Z4K3_HUMAN,tr|A0A3B3ISX1|A0A3B3ISX1_HUMAN" 6 1107.6288 0.99 30076 14290 2 1107.625679 554.8217 Double-stranded RNA-specific adenosine deaminase OS=Homo sapiens OX=9606 GN=ADAR PE=1 SV=4 6 2699.6 - 1.96E+06 - - - -2.8259 - 1.971 0.286 - 279.1 1 2 0 -0.0031 11 0 0 0 6.96E+07 7.02E+07 - - - 2.988 1 221125_WJC_METTL3_EV_vs_WT_F03.14291.14291.3 5.66E-12 24/84 K.DHTPSQELALTQSVGGDSSADR[166.11].L "sp|Q86U44|MTA70_HUMAN,tr|H0YFV6|H0YFV6_HUMAN" 2 2280.0494 0.001 30077 14291 3 2280.045407 761.0237 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 4.22 2699.8 - 1.40E+06 - - - -1.7368 - 4.485 0.717 - 639.1 1 2 0 -0.004 22 0 0 0 0.00E+00 2.65E+07 - - - 10.0907 0.9991 221125_WJC_METTL3_EV_vs_WT_F03.14292.14292.2 1.12E-05 26-Oct K.EVTTLTADPPDGIK[136.11].V "sp|Q16763|UBE2S_HUMAN,tr|K7EM75|K7EM75_HUMAN,tr|K7EPJ1|K7EPJ1_HUMAN" 3 1463.7599 1.68 30078 14292 2 1463.755705 732.8872 Ubiquitin-conjugating enzyme E2 S OS=Homo sapiens OX=9606 GN=UBE2S PE=1 SV=2 4.03 2699.9 - 842656 - - - -2.8591 - 1.864 0.461 - 115.4 1 2 0 -0.0042 14 0 0 0 2.84E+07 1.69E+07 - - - 4.0073 1 221125_WJC_METTL3_EV_vs_WT_F03.14293.14293.2 6.23E-09 24-Dec K.YTDLNSNDVTGLR[166.11].E "sp|Q15007|FL2D_HUMAN,tr|A0A087X1R4|A0A087X1R4_HUMAN" 2 1476.7084 1.02 30079 14293 2 1476.701458 739.3615 Pre-mRNA-splicing regulator WTAP OS=Homo sapiens OX=9606 GN=WTAP PE=1 SV=2 4.21 2700 - 689724 - - - -4.7057 - 2.612 0.681 - 433.6 1 2 0 -0.0069 13 0 0 0 8.44E+06 8.24E+06 - - - 6.5329 0.9817 221125_WJC_METTL3_EV_vs_WT_F03.14296.14296.2 0.133 16-Sep R.SGVSLAALK.K "sp|P10412|H14_HUMAN,sp|P16403|H12_HUMAN,sp|P16402|H13_HUMAN" 3 844.5018 0.74 30080 14296 2 844.500459 423.2582 Histone H1.4 OS=Homo sapiens OX=9606 GN=H1-4 PE=1 SV=2 8.47 2700.4 - 6.31E+06 - - - -1.6092 - 1.576 0.026 - 255.4 1 2 0 -0.0014 9 0 0 0 1.97E+08 2.68E+08 - - - 0.5486 0.9998 221125_WJC_METTL3_EV_vs_WT_F03.14297.14297.2 0.0017 16-Oct R.QDIAFAYQR.R "sp|P07355|ANXA2_HUMAN,tr|H0YMU9|H0YMU9_HUMAN,tr|H0YKX9|H0YKX9_HUMAN,tr|H0YMM1|H0YMM1_HUMAN,tr|H0YLV6|H0YLV6_HUMAN,tr|H0YM50|H0YM50_HUMAN,tr|H0YMD0|H0YMD0_HUMAN,tr|H0YKV8|H0YKV8_HUMAN,tr|H0YMW4|H0YMW4_HUMAN,tr|H0YN42|H0YN42_HUMAN,tr|A0A7I2V4P4|A0A7I2V4P4_HUMAN,tr|H0YMT9|H0YMT9_HUMAN,tr|H0YKZ7|H0YKZ7_HUMAN,tr|H0YKL9|H0YKL9_HUMAN,tr|H0YNB8|H0YNB8_HUMAN,tr|H0YKS4|H0YKS4_HUMAN" 16 1110.5458 4.36 30081 14297 2 1110.54454 556.2802 Annexin A2 OS=Homo sapiens OX=9606 GN=ANXA2 PE=1 SV=2 5.84 2700.5 - 4.90E+06 - - - -1.1418 - 2.189 0.391 - 460.9 1 2 0 -0.0013 9 0 0 0 2.91E+08 6.66E+07 - - - 4.1951 0.9997 221125_WJC_METTL3_EV_vs_WT_F03.14298.14298.3 0.114 13/36 K.LNLVVK[136.11]PLEK[136.11].V "sp|P11441|UBL4A_HUMAN,tr|Q5HY81|Q5HY81_HUMAN" 2 1167.7562 1.64 30082 14298 3 1167.753136 390.2593 Ubiquitin-like protein 4A OS=Homo sapiens OX=9606 GN=UBL4A PE=1 SV=1 8.59 2700.5 - 3.64E+06 - - - -2.6196 - 2.11 0.389 - 169.4 1 2 0 -0.0031 10 0 0 0 1.23E+08 7.52E+07 - - - 5.0568 0.9346 221125_WJC_METTL3_EV_vs_WT_F03.14299.14299.2 0.0138 14-Aug L.TLVFVETK.K "sp|O00571|DDX3X_HUMAN,sp|O15523|DDX3Y_HUMAN,sp|P17844|DDX5_HUMAN,tr|A0A2R8YFR4|A0A2R8YFR4_HUMAN,tr|A0A2R8YCW1|A0A2R8YCW1_HUMAN,tr|A0A7I2V5F5|A0A7I2V5F5_HUMAN,tr|A0A2R8YDH3|A0A2R8YDH3_HUMAN,tr|A0A2R8YDT5|A0A2R8YDT5_HUMAN,tr|A0A2R8Y645|A0A2R8Y645_HUMAN,tr|A0A2R8YF78|A0A2R8YF78_HUMAN,tr|A0A0D9SFB3|A0A0D9SFB3_HUMAN,tr|A0A2R8YFS5|A0A2R8YFS5_HUMAN,tr|J3QSF1|J3QSF1_HUMAN,tr|A0A7I2V507|A0A7I2V507_HUMAN,tr|A0A0D9SF53|A0A0D9SF53_HUMAN,tr|J3KTA4|J3KTA4_HUMAN,tr|A0A0J9YVQ7|A0A0J9YVQ7_HUMAN,tr|A0A0G2JLI4|A0A0G2JLI4_HUMAN,tr|A0A2R8Y5G6|A0A2R8Y5G6_HUMAN,tr|A0A2R8Y7T2|A0A2R8Y7T2_HUMAN,tr|A0A0D9SG12|A0A0D9SG12_HUMAN,tr|A0A7I2V2S0|A0A7I2V2S0_HUMAN,tr|F6S8Q4|F6S8Q4_HUMAN,tr|A0A2U3TZJ9|A0A2U3TZJ9_HUMAN,tr|A0A2R8Y4A4|A0A2R8Y4A4_HUMAN" 25 935.5328 1.7 30083 14299 2 935.531151 468.7737 ATP-dependent RNA helicase DDX3X OS=Homo sapiens OX=9606 GN=DDX3X PE=1 SV=3 5.66 2700.6 - 2.64E+06 - - - -1.7455 - 1.335 0.388 - 194.9 1 1 0 -0.0016 8 0 0 0 5.86E+07 3.44E+07 - - - 2.7777 0.898 221125_WJC_METTL3_EV_vs_WT_F03.14300.14300.2 0.0406 14-Sep L.TLVFVETK[136.11].K "sp|O00571|DDX3X_HUMAN,sp|O15523|DDX3Y_HUMAN,sp|P17844|DDX5_HUMAN,tr|A0A2R8YFR4|A0A2R8YFR4_HUMAN,tr|A0A2R8YCW1|A0A2R8YCW1_HUMAN,tr|A0A7I2V5F5|A0A7I2V5F5_HUMAN,tr|A0A2R8YDH3|A0A2R8YDH3_HUMAN,tr|A0A2R8YDT5|A0A2R8YDT5_HUMAN,tr|A0A2R8Y645|A0A2R8Y645_HUMAN,tr|A0A2R8YF78|A0A2R8YF78_HUMAN,tr|A0A0D9SFB3|A0A0D9SFB3_HUMAN,tr|A0A2R8YFS5|A0A2R8YFS5_HUMAN,tr|J3QSF1|J3QSF1_HUMAN,tr|A0A7I2V507|A0A7I2V507_HUMAN,tr|A0A0D9SF53|A0A0D9SF53_HUMAN,tr|J3KTA4|J3KTA4_HUMAN,tr|A0A0J9YVQ7|A0A0J9YVQ7_HUMAN,tr|A0A0G2JLI4|A0A0G2JLI4_HUMAN,tr|A0A2R8Y5G6|A0A2R8Y5G6_HUMAN,tr|A0A2R8Y7T2|A0A2R8Y7T2_HUMAN,tr|A0A0D9SG12|A0A0D9SG12_HUMAN,tr|A0A7I2V2S0|A0A7I2V2S0_HUMAN,tr|F6S8Q4|F6S8Q4_HUMAN,tr|A0A2U3TZJ9|A0A2U3TZJ9_HUMAN,tr|A0A2R8Y4A4|A0A2R8Y4A4_HUMAN" 25 943.547 1.7 30084 14300 2 943.544697 472.7808 ATP-dependent RNA helicase DDX3X OS=Homo sapiens OX=9606 GN=DDX3X PE=1 SV=3 5.66 2700.7 - 2.13E+06 - - - -2.4238 - 1.495 0.341 - 253.5 1 1 0 -0.0023 8 0 0 0 5.86E+07 3.44E+07 - - - 2.7717 0.9998 221125_WJC_METTL3_EV_vs_WT_F03.14305.14305.2 9.37E-06 22-Oct K.AYLEEEC[160.03]PATLR.K "sp|P25311|ZA2G_HUMAN,tr|C9JEV0|C9JEV0_HUMAN" 2 1450.6762 1170.01 30087 14305 2 1450.674128 726.3454 Zinc-alpha-2-glycoprotein OS=Homo sapiens OX=9606 GN=AZGP1 PE=1 SV=2 4.25 2701.2 - 6.96E+06 - - - -1.449 - 2.371 0.44 - 391.5 1 2 0 -0.0021 12 0 0 0 2.61E+08 2.23E+05 - - - 4.5617 0.9997 221125_WJC_METTL3_EV_vs_WT_F03.14306.14306.2 1.54E-05 20-Nov K.TPAQFDADELR.A "sp|P04083|ANXA1_HUMAN,tr|Q5T3N1|Q5T3N1_HUMAN" 2 1261.5939 999 30088 14306 2 1261.591819 631.8042 Annexin A1 OS=Homo sapiens OX=9606 GN=ANXA1 PE=1 SV=2 4.03 2701.3 - 1.13E+07 - - - -1.6344 - 2.261 0.413 - 586.1 1 2 0 -0.0021 11 0 0 0 1.09E+08 0.00E+00 - - - 4.2977 0.9949 221125_WJC_METTL3_EV_vs_WT_F03.14308.14308.2 0.0433 14-Oct K.NIITNLSK.C sp|P11387|TOP1_HUMAN 1 901.5233 0.79 30090 14308 2 901.520863 451.7689 DNA topoisomerase 1 OS=Homo sapiens OX=9606 GN=TOP1 PE=1 SV=2 8.75 2701.4 - 2.94E+06 - - - -2.6832 - 1.493 0.244 - 326.5 1 2 0 -0.0024 8 0 0 0 6.60E+07 8.37E+07 - - - 2.0512 0.9991 221125_WJC_METTL3_EV_vs_WT_F03.14310.14310.2 0.0013 14-Aug K.EENFFGPK[136.11].E sp|Q9NZI8|IF2B1_HUMAN 1 974.4589 1.61 30092 14310 2 974.45683 488.2367 Insulin-like growth factor 2 mRNA-binding protein 1 OS=Homo sapiens OX=9606 GN=IGF2BP1 PE=1 SV=2 4.53 2701.6 - 1.36E+06 - - - -2.1212 - 1.492 0.414 - 233.1 1 2 0 -0.0021 8 0 0 0 2.96E+07 1.84E+07 - - - 3.3049 0.9998 221125_WJC_METTL3_EV_vs_WT_F03.14313.14313.2 0.00086 20-Oct K.SLTANPELIDR.L "sp|Q9Y2L1|RRP44_HUMAN,tr|F2Z2C0|F2Z2C0_HUMAN,tr|G3V1J5|G3V1J5_HUMAN" 3 1227.6459 2.14 30093 14313 2 1227.645683 614.8302 Exosome complex exonuclease RRP44 OS=Homo sapiens OX=9606 GN=DIS3 PE=1 SV=2 4.37 2702 - 4.29E+06 - - - -0.1898 - 2.119 0.417 - 390.5 1 2 0 -0.0002 11 0 0 0 4.05E+08 1.89E+08 - - - 4.1524 0.9999 221125_WJC_METTL3_EV_vs_WT_F03.14314.14314.3 0.000261 Nov-40 K.KEPILVC[160.03]PPLR.S sp|Q8N5N7|RM50_HUMAN 1 1320.7588 0.86 30094 14314 3 1320.757469 441.2602 "39S ribosomal protein L50, mitochondrial OS=Homo sapiens OX=9606 GN=MRPL50 PE=1 SV=2" 8.22 2702.1 - 1.11E+06 - - - -0.9911 - 1.946 0.445 - 210.5 1 2 0 -0.0013 11 0 0 0 3.23E+07 3.74E+07 - - - 5.3923 0.9993 221125_WJC_METTL3_EV_vs_WT_F03.14317.14317.2 8.01E-05 20-Oct K.ENGLPLEYQEK.L "sp|O75223|GGCT_HUMAN,tr|M0QZK8|M0QZK8_HUMAN" 2 1318.6405 999 30097 14317 2 1318.637565 660.3275 Gamma-glutamylcyclotransferase OS=Homo sapiens OX=9606 GN=GGCT PE=1 SV=1 4.25 2702.4 - 1.17E+06 - - - -2.2227 - 1.814 0.414 - 176.4 1 2 0 -0.0029 11 0 0 0 2.56E+07 0.00E+00 - - - 3.7089 0.9995 221125_WJC_METTL3_EV_vs_WT_F03.14320.14320.2 0.0154 14/22 R.IASLEVENQSLR.G "sp|P29692|EF1D_HUMAN,tr|E9PI39|E9PI39_HUMAN,tr|E9PMW7|E9PMW7_HUMAN,tr|E9PQ49|E9PQ49_HUMAN,tr|A0A087X1X7|A0A087X1X7_HUMAN,tr|E9PL12|E9PL12_HUMAN,tr|H0YCK7|H0YCK7_HUMAN,tr|E9PIZ1|E9PIZ1_HUMAN,tr|E9PN91|E9PN91_HUMAN,tr|E9PPR1|E9PPR1_HUMAN,tr|E9PRY8|E9PRY8_HUMAN,tr|E9PK01|E9PK01_HUMAN,tr|E9PL71|E9PL71_HUMAN" 13 1357.7201 1.57 30098 14320 2 1357.723258 679.8673 Elongation factor 1-delta OS=Homo sapiens OX=9606 GN=EEF1D PE=1 SV=5 4.53 2702.8 - 4.51E+06 - - - 2.2936 - 2.652 0.365 - 859.7 1 2 0 0.0031 12 0 0 0 5.84E+08 3.73E+08 - - - 4.3021 1 221125_WJC_METTL3_EV_vs_WT_F03.14324.14324.3 2.58E-10 16/48 K.YGGPYHIGGSPFK[136.11].A "sp|P21333|FLNA_HUMAN,tr|A0A7P0NMY4|A0A7P0NMY4_HUMAN,tr|Q60FE5|Q60FE5_HUMAN" 3 1386.6812 0.55 30101 14324 3 1386.676679 463.2343 Filamin-A OS=Homo sapiens OX=9606 GN=FLNA PE=1 SV=4 8.5 2703.3 - 744773 - - - -3.2502 - 2.817 0.603 - 197.3 1 2 0 -0.0045 13 0 0 0 9.19E+06 1.67E+07 - - - 8.0696 0.998 221125_WJC_METTL3_EV_vs_WT_F03.14325.14325.2 0.0047 16-Jul R.DTYVSSFPR.A "sp|P23193|TCEA1_HUMAN,tr|A0A1W2PRL9|A0A1W2PRL9_HUMAN,tr|A0A1W2PPZ5|A0A1W2PPZ5_HUMAN" 3 1070.5033 1.12 30102 14325 2 1070.500548 536.2589 Transcription elongation factor A protein 1 OS=Homo sapiens OX=9606 GN=TCEA1 PE=1 SV=2 5.84 2703.4 - 655980 - - - -2.5474 - 1.463 0.358 - 150.7 1 2 0 -0.0027 9 0 0 0 7.24E+07 6.47E+07 - - - 2.7851 0.9998 221125_WJC_METTL3_EV_vs_WT_F03.14329.14329.2 2.62E-05 20-Oct R.NPEAALSPTFR[166.11].S "sp|Q86U44|MTA70_HUMAN,tr|B4E349|B4E349_HUMAN,tr|F5H6D8|F5H6D8_HUMAN,tr|B4DTN4|B4DTN4_HUMAN" 4 1211.6174 1.07 30104 14329 2 1211.615491 606.816 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 6 2704 - 8.91E+06 - - - -1.5814 - 2.427 0.511 - 564.4 1 2 0 -0.0019 11 0 0 0 6.37E+07 5.94E+07 - - - 5.2133 0.9481 221125_WJC_METTL3_EV_vs_WT_F03.14331.14331.2 0.00579 18-Sep L.NLQIDPTIQR.V sp|P02538|K2C6A_HUMAN 1 1196.6513 50.06 30106 14331 2 1196.650303 599.3329 "Keratin, type II cytoskeletal 6A OS=Homo sapiens OX=9606 GN=KRT6A PE=1 SV=3" 5.84 2704 - 2.57E+07 - - - -0.8632 - 1.85 0.245 - 274.8 1 1 0 -0.001 10 0 0 0 7.16E+08 1.43E+07 - - - 2.5674 0.9964 221125_WJC_METTL3_EV_vs_WT_F03.14333.14333.2 0.0291 16-Aug R.IVLQIDNAR[166.11].L "sp|P05783|K1C18_HUMAN,sp|P08727|K1C19_HUMAN,tr|F8VZY9|F8VZY9_HUMAN,tr|C9JM50|C9JM50_HUMAN" 4 1050.6061 1.94 30108 14333 2 1050.608538 526.3103 "Keratin, type I cytoskeletal 18 OS=Homo sapiens OX=9606 GN=KRT18 PE=1 SV=2" 5.84 2704.3 - 695734 - - - 2.3072 - 1.687 0.217 - 191.6 1 2 0 0.0024 9 0 0 0 6.29E+07 3.25E+07 - - - 2.1559 0.9992 221125_WJC_METTL3_EV_vs_WT_F03.14337.14337.2 0.00102 18-Jul R.RAIEQLAAMD.- "sp|O15392|BIRC5_HUMAN,tr|A0A0B4J1S3|A0A0B4J1S3_HUMAN,tr|H3BLT4|H3BLT4_HUMAN" 3 1116.5597 3.37 30110 14337 2 1116.560534 559.2871 Baculoviral IAP repeat-containing protein 5 OS=Homo sapiens OX=9606 GN=BIRC5 PE=1 SV=3 4.67 2704.8 - 2.85E+06 - - - 0.7075 - 1.408 0.362 - 170.2 1 2 0 0.0008 10 0 0 0 7.93E+07 2.35E+07 - - - 2.6696 1 221125_WJC_METTL3_EV_vs_WT_F03.14338.14338.3 9.26E-06 15/44 R.ATVVVGDLHPLR[166.11].D "sp|Q9NSI2|SLX9_HUMAN,tr|C9JJU7|C9JJU7_HUMAN" 2 1285.7382 1.66 30111 14338 3 1285.736553 429.5867 Ribosome biogenesis protein SLX9 homolog OS=Homo sapiens OX=9606 GN=SLX9 PE=1 SV=2 6.79 2704.9 - 3.00E+06 - - - -1.2732 - 2.878 0.427 - 461.9 1 2 0 -0.0016 12 0 0 0 9.37E+08 5.65E+08 - - - 6.2303 0.9998 221125_WJC_METTL3_EV_vs_WT_F03.14340.14340.3 0.00121 Nov-40 R.NPEAALSPTFR[166.11].S "sp|Q86U44|MTA70_HUMAN,tr|B4E349|B4E349_HUMAN,tr|F5H6D8|F5H6D8_HUMAN,tr|B4DTN4|B4DTN4_HUMAN" 4 1211.6174 0.02 30113 14340 3 1211.616729 404.8797 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 6 2705 - 1.40E+06 - - - -0.5596 - 2.087 0.339 - 240.9 1 2 0 -0.0007 11 0 0 0 9.45E+08 4.02E+10 - - - 4.4094 0.9588 221125_WJC_METTL3_EV_vs_WT_F03.14343.14343.2 0.261 16-Jul R.EDMESVLDK.M sp|P08240|SRPRA_HUMAN 1 1064.4696 2.83 30116 14343 2 1064.468463 533.2421 Signal recognition particle receptor subunit alpha OS=Homo sapiens OX=9606 GN=SRPRA PE=1 SV=2 3.92 2705.4 - 574891 - - - -1.0597 - 1.128 0.058 - 97.7 1 2 0 -0.0011 9 0 0 0 2.06E+07 7.28E+06 - - - -0.1825 0.9997 221125_WJC_METTL3_EV_vs_WT_F03.14344.14344.2 0.000417 22-Sep K.EPISVSSEQVLK[136.11].F sp|P00918|CAH2_HUMAN 1 1322.7173 0.57 30117 14344 2 1322.716637 662.3659 Carbonic anhydrase 2 OS=Homo sapiens OX=9606 GN=CA2 PE=1 SV=2 4.53 2705.5 - 558681 - - - -0.499 - 1.77 0.415 - 264.5 1 2 0 -0.0007 12 0 0 0 4.71E+06 8.30E+06 - - - 3.6083 0.9998 221125_WJC_METTL3_EV_vs_WT_F03.14346.14346.2 0.000112 22-Sep R.ATVVVGDLHPLR[166.11].D "sp|Q9NSI2|SLX9_HUMAN,tr|C9JJU7|C9JJU7_HUMAN" 2 1285.7382 1.71 30119 14346 2 1285.738112 643.8764 Ribosome biogenesis protein SLX9 homolog OS=Homo sapiens OX=9606 GN=SLX9 PE=1 SV=2 6.79 2705.8 - 359263 - - - -0.0607 - 2.357 0.36 - 271.4 1 2 0 -0.0001 12 0 0 0 1.98E+08 1.16E+08 - - - 3.9559 0.9999 221125_WJC_METTL3_EV_vs_WT_F03.14349.14349.3 0.00217 Dec-32 R.TFLLEYHNR.V "sp|Q9UNH7|SNX6_HUMAN,tr|A0A0A0MRI2|A0A0A0MRI2_HUMAN,tr|G3V5X9|G3V5X9_HUMAN" 3 1191.6037 3.89 30121 14349 3 1191.601627 398.2085 Sorting nexin-6 OS=Homo sapiens OX=9606 GN=SNX6 PE=1 SV=1 6.41 2706.2 - 1.33E+06 - - - -1.7036 - 2.104 0.405 - 215.7 1 2 0 -0.002 9 0 0 0 3.65E+09 9.37E+08 - - - 5.2966 1 221125_WJC_METTL3_EV_vs_WT_F03.14351.14351.3 4.51E-05 14/44 R.ATVVVGDLHPLR.D "sp|Q9NSI2|SLX9_HUMAN,tr|C9JJU7|C9JJU7_HUMAN" 2 1275.7299 1.66 30122 14351 3 1275.728648 426.2506 Ribosome biogenesis protein SLX9 homolog OS=Homo sapiens OX=9606 GN=SLX9 PE=1 SV=2 6.79 2706.4 - 8.51E+06 - - - -0.9971 - 2.467 0.44 - 365.1 1 2 0 -0.0013 12 0 0 0 9.37E+08 5.65E+08 - - - 5.9482 0.9997 221125_WJC_METTL3_EV_vs_WT_F03.14352.14352.2 0.000108 13/20 R.YLAEFATGNDR[166.11].K "sp|P62258|1433E_HUMAN,tr|K7EM20|K7EM20_HUMAN" 2 1265.5916 1.8 30123 14352 2 1265.589026 633.8031 14-3-3 protein epsilon OS=Homo sapiens OX=9606 GN=YWHAE PE=1 SV=1 4.37 2706.4 - 3.44E+06 - - - -2.0228 - 2.41 0.407 - 607.5 1 2 0 -0.0026 11 0 0 0 2.64E+08 1.47E+08 - - - 4.4259 1 221125_WJC_METTL3_EV_vs_WT_F03.14353.14353.2 9.08E-07 13/24 R.FSGSGSGTDFTLK.L "sp|A2NJV5|KV229_HUMAN,sp|A0A087WW87|KV240_HUMAN,sp|P06310|KV230_HUMAN,sp|A0A075B6S2|KVD29_HUMAN,sp|P01614|KVD40_HUMAN,sp|P01615|KVD28_HUMAN,sp|A0A075B6S6|KVD30_HUMAN,sp|A0A075B6P5|KV228_HUMAN,sp|A0A0A0MRZ7|KVD26_HUMAN" 9 1302.6092 1140 30124 14353 2 1302.608731 652.3119 Immunoglobulin kappa variable 2-29 OS=Homo sapiens OX=9606 GN=IGKV2-29 PE=3 SV=2 5.84 2706.5 - 3.31E+06 - - - -0.357 - 2.592 0.618 - 349.5 1 2 0 -0.0005 13 0 0 0 7.78E+09 6.83E+06 - - - 6.0498 0.9996 221125_WJC_METTL3_EV_vs_WT_F03.14356.14356.2 0.0216 16-Sep R.IVLQIDNAR.L "sp|P05783|K1C18_HUMAN,sp|P08727|K1C19_HUMAN,tr|F8VZY9|F8VZY9_HUMAN,tr|C9JM50|C9JM50_HUMAN" 4 1040.5978 1.94 30125 14356 2 1040.59864 521.3062 "Keratin, type I cytoskeletal 18 OS=Homo sapiens OX=9606 GN=KRT18 PE=1 SV=2" 5.84 2706.9 - 3.65E+06 - - - 0.7649 - 1.841 0.372 - 312.8 1 2 0 0.0008 9 0 0 0 6.29E+07 3.25E+07 - - - 3.554 0.9998 221125_WJC_METTL3_EV_vs_WT_F03.14357.14357.2 0.000149 16-Oct R.NVIEAVYSR.L "sp|O75688|PPM1B_HUMAN,tr|B8ZZF0|B8ZZF0_HUMAN,tr|A0A3B3IS24|A0A3B3IS24_HUMAN,tr|C9JIR6|C9JIR6_HUMAN" 4 1049.5506 3.31 30126 14357 2 1049.549115 525.7826 Protein phosphatase 1B OS=Homo sapiens OX=9606 GN=PPM1B PE=1 SV=1 6 2706.9 - 2.72E+06 - - - -1.3758 - 2.077 0.465 - 351.5 1 2 0 -0.0014 9 0 0 0 1.07E+09 3.25E+08 - - - 4.5896 0.9771 221125_WJC_METTL3_EV_vs_WT_F03.14358.14358.3 0.0298 Oct-44 R.VGMAHPYESWYK[136.11].S sp|P0CG40|SP9_HUMAN 1 1474.6795 2.17 30127 14358 3 1474.673947 492.5671 Transcription factor Sp9 OS=Homo sapiens OX=9606 GN=SP9 PE=3 SV=1 6.72 2707.1 - 834091 - - - -3.7459 - 1.527 0.245 - 100.6 1 2 0 -0.0055 12 0 0 0 1.97E+07 9.09E+06 - - - 2.4433 0.9989 221125_WJC_METTL3_EV_vs_WT_F03.14359.14359.2 8.00E-05 18-Sep R.MDQYFNQMEK[136.11].L "sp|O43432|IF4G3_HUMAN,sp|Q04637|IF4G1_HUMAN,tr|A0A804HJV5|A0A804HJV5_HUMAN,tr|H7C044|H7C044_HUMAN,tr|E7EUU4|E7EUU4_HUMAN,tr|E9PGM1|E9PGM1_HUMAN,tr|A0A0U1RQK7|A0A0U1RQK7_HUMAN,tr|A0A0A0MSA7|A0A0A0MSA7_HUMAN,tr|E7EX73|E7EX73_HUMAN,tr|A0A7I2Y1C3|A0A7I2Y1C3_HUMAN" 10 1340.5621 0.65 30128 14359 2 1340.558569 671.2883 Eukaryotic translation initiation factor 4 gamma 3 OS=Homo sapiens OX=9606 GN=EIF4G3 PE=1 SV=2 4.37 2707.2 - 820836 - - - -2.6026 - 1.787 0.379 - 309.4 1 2 0 -0.0035 10 0 0 0 9.72E+06 1.50E+07 - - - 3.4597 0.9075 221125_WJC_METTL3_EV_vs_WT_F03.14360.14360.2 0.436 14-Jul L.ANLLQIQR.H "sp|Q9Y224|RTRAF_HUMAN,tr|G3V4C6|G3V4C6_HUMAN,tr|H0YJB9|H0YJB9_HUMAN" 3 954.5611 1.22 30129 14360 2 954.560792 478.2878 "RNA transcription, translation and transport factor protein OS=Homo sapiens OX=9606 GN=RTRAF PE=1 SV=1" 9.79 2707.3 - 817285 - - - -0.2849 - 1.665 0.182 - 220.2 1 1 0 -0.0003 8 0 0 0 2.35E+07 1.93E+07 - - - 1.9228 0.9995 221125_WJC_METTL3_EV_vs_WT_F03.14361.14361.3 1.85E-05 13/52 K.ILIANTGMDTDK[136.11]IK[136.11].L "sp|P78371|TCPB_HUMAN,tr|F8VQ14|F8VQ14_HUMAN,tr|F5GWF6|F5GWF6_HUMAN" 3 1547.8564 0.4 30130 14361 3 1547.855049 516.9594 T-complex protein 1 subunit beta OS=Homo sapiens OX=9606 GN=CCT2 PE=1 SV=4 5.96 2707.5 - 433760 - - - -0.8599 - 2.548 0.359 - 156.9 1 2 1 -0.0013 14 0 0 0 3.68E+08 9.16E+08 - - - 5.0277 0.9997 221125_WJC_METTL3_EV_vs_WT_F03.14365.14365.2 0.000924 16-Sep R.LSESQLSFR[166.11].R sp|Q96PK6|RBM14_HUMAN 1 1075.5537 1.79 30132 14365 2 1075.551507 538.7841 RNA-binding protein 14 OS=Homo sapiens OX=9606 GN=RBM14 PE=1 SV=2 6 2707.9 - 5.87E+06 - - - -2.0799 - 2.166 0.438 - 319.9 1 2 0 -0.0022 9 0 0 0 6.77E+09 3.79E+09 - - - 4.5114 0.9996 221125_WJC_METTL3_EV_vs_WT_F03.14368.14368.2 0.0227 16-Jul R.DTYVSSFPR[166.11].A "sp|P23193|TCEA1_HUMAN,tr|A0A1W2PRL9|A0A1W2PRL9_HUMAN,tr|A0A1W2PPZ5|A0A1W2PPZ5_HUMAN" 3 1080.5115 1.15 30135 14368 2 1080.510531 541.263 Transcription elongation factor A protein 1 OS=Homo sapiens OX=9606 GN=TCEA1 PE=1 SV=2 5.84 2708 - 2.87E+06 - - - -0.9384 - 1.557 0.406 - 124 1 2 0 -0.001 9 0 0 0 7.42E+07 6.47E+07 - - - 3.3203 0.9999 221125_WJC_METTL3_EV_vs_WT_F03.14369.14369.3 0.000137 Oct-32 R.VVHIMDFQR[166.11].G "sp|P43243|MATR3_HUMAN,tr|D6RE02|D6RE02_HUMAN,tr|B3KM87|B3KM87_HUMAN,tr|A8MXP9|A8MXP9_HUMAN,tr|D6RAY2|D6RAY2_HUMAN,tr|D6R991|D6R991_HUMAN,tr|A0A0R4J2E8|A0A0R4J2E8_HUMAN,tr|D6RAM9|D6RAM9_HUMAN,tr|D6RIA2|D6RIA2_HUMAN,tr|H0Y8T4|H0Y8T4_HUMAN,tr|D6REM6|D6REM6_HUMAN,tr|D6RBI2|D6RBI2_HUMAN" 12 1153.5942 1.19 30136 14369 3 1153.592524 385.5387 Matrin-3 OS=Homo sapiens OX=9606 GN=MATR3 PE=1 SV=2 6.71 2708.1 - 2.66E+06 - - - -1.426 - 1.856 0.452 - 189.5 1 2 0 -0.0016 9 0 0 0 7.50E+09 6.32E+09 - - - 5.4427 1 221125_WJC_METTL3_EV_vs_WT_F03.14370.14370.3 9.98E-08 15/32 R.VVHIMDFQR.G "sp|P43243|MATR3_HUMAN,tr|D6RE02|D6RE02_HUMAN,tr|B3KM87|B3KM87_HUMAN,tr|A8MXP9|A8MXP9_HUMAN,tr|D6RAY2|D6RAY2_HUMAN,tr|D6R991|D6R991_HUMAN,tr|A0A0R4J2E8|A0A0R4J2E8_HUMAN,tr|D6RAM9|D6RAM9_HUMAN,tr|D6RIA2|D6RIA2_HUMAN,tr|H0Y8T4|H0Y8T4_HUMAN,tr|D6REM6|D6REM6_HUMAN,tr|D6RBI2|D6RBI2_HUMAN" 12 1143.5859 1.19 30137 14370 3 1143.584082 382.2026 Matrin-3 OS=Homo sapiens OX=9606 GN=MATR3 PE=1 SV=2 6.71 2708.2 - 1.56E+06 - - - -1.5889 - 2.421 0.533 - 519.5 1 2 0 -0.0018 9 0 0 0 7.49E+09 6.31E+09 - - - 7.1467 0.9987 221125_WJC_METTL3_EV_vs_WT_F03.14371.14371.2 2.15E-05 22-Oct M.PYQYPALTPEQK[136.11].K "sp|P04075|ALDOA_HUMAN,tr|H3BR04|H3BR04_HUMAN,tr|H3BMQ8|H3BMQ8_HUMAN,tr|H3BQN4|H3BQN4_HUMAN,tr|H3BUH7|H3BUH7_HUMAN,tr|J3KPS3|J3KPS3_HUMAN,tr|H3BPS8|H3BPS8_HUMAN" 7 1441.7333 1.4 30138 14371 2 1441.728138 721.8739 Fructose-bisphosphate aldolase A OS=Homo sapiens OX=9606 GN=ALDOA PE=1 SV=2 6.42 2708.4 - 845372 - - - -3.5672 - 1.917 0.453 - 311.6 1 2 0 -0.0051 12 0 0 0 4.29E+07 3.06E+07 - - - 4.0975 0.9974 221125_WJC_METTL3_EV_vs_WT_F03.14372.14372.3 0.0188 17/40 R.LLASTLVHSVK.K "sp|Q9NYF8|BCLF1_HUMAN,tr|E9PKI6|E9PKI6_HUMAN,tr|A0A1W2PQ43|A0A1W2PQ43_HUMAN,tr|E9PK91|E9PK91_HUMAN,tr|E9PJA7|E9PJA7_HUMAN,tr|E9PK09|E9PK09_HUMAN,tr|E9PQN2|E9PQN2_HUMAN" 7 1166.7023 2.36 30139 14372 3 1166.700262 389.908 Bcl-2-associated transcription factor 1 OS=Homo sapiens OX=9606 GN=BCLAF1 PE=1 SV=2 8.76 2708.5 - 640595 - - - -1.7545 - 2.094 0.207 - 196 1 2 0 -0.002 11 0 0 0 8.49E+06 3.60E+06 - - - 2.9469 0.8088 221125_WJC_METTL3_EV_vs_WT_F03.14376.14376.2 0.00011 18-Oct T.VVVGDLHPLR.D "sp|Q9NSI2|SLX9_HUMAN,tr|C9JJU7|C9JJU7_HUMAN" 2 1103.6451 3.43 30141 14376 2 1103.641495 552.8298 Ribosome biogenesis protein SLX9 homolog OS=Homo sapiens OX=9606 GN=SLX9 PE=1 SV=2 6.71 2709 - 1.36E+06 - - - -3.2918 - 2.023 0.227 - 399.2 1 1 0 -0.0036 10 0 0 0 2.84E+07 8.28E+06 - - - 2.6832 0.9934 221125_WJC_METTL3_EV_vs_WT_F03.14383.14383.2 0.146 12-Jul K.DLEIQMK.K "sp|Q9NP61|ARFG3_HUMAN,tr|H0Y6A0|H0Y6A0_HUMAN" 2 875.4423 1.33 30145 14383 2 875.440214 438.7284 ADP-ribosylation factor GTPase-activating protein 3 OS=Homo sapiens OX=9606 GN=ARFGAP3 PE=1 SV=1 4.37 2709.7 - 1.72E+06 - - - -2.3303 - 1.392 0.21 - 155.3 1 2 0 -0.002 7 0 0 0 3.33E+07 2.50E+07 - - - 1.6394 0.9318 221125_WJC_METTL3_EV_vs_WT_F03.14385.14385.2 0.00756 16-Sep R.TYSLGSALR[166.11].P "sp|P08670|VIME_HUMAN,tr|B0YJC4|B0YJC4_HUMAN,tr|A0A1B0GVG8|A0A1B0GVG8_HUMAN,tr|A0A1B0GTT5|A0A1B0GTT5_HUMAN" 4 976.5217 0.97 30147 14385 2 976.520079 489.2681 Vimentin OS=Homo sapiens OX=9606 GN=VIM PE=1 SV=4 8.41 2709.9 - 4.08E+06 - - - -1.6753 - 1.409 0.36 - 250.2 1 1 0 -0.0016 9 0 0 0 4.52E+07 4.67E+07 - - - 2.6914 0.9972 221125_WJC_METTL3_EV_vs_WT_F03.14389.14389.2 0.0326 20-Sep R.YLAEFATGNDR.K "sp|P62258|1433E_HUMAN,tr|K7EM20|K7EM20_HUMAN" 2 1255.5833 1.99 30149 14389 2 1255.578269 628.7989 14-3-3 protein epsilon OS=Homo sapiens OX=9606 GN=YWHAE PE=1 SV=1 4.37 2710.4 - 1.27E+07 - - - -4.0196 - 1.965 0.368 - 300.3 1 2 0 -0.005 11 0 0 0 2.92E+08 1.47E+08 - - - 3.5848 0.9991 221125_WJC_METTL3_EV_vs_WT_F03.14391.14391.2 1.54E-06 20-Oct R.C[160.03]TPAC[160.03]ISFGPK[136.11].N "sp|P34932|HSP74_HUMAN,tr|A0A087WTS8|A0A087WTS8_HUMAN,tr|A0A087WYC1|A0A087WYC1_HUMAN" 3 1244.5773 0.24 30150 14391 2 1244.572653 623.2959 Heat shock 70 kDa protein 4 OS=Homo sapiens OX=9606 GN=HSPA4 PE=1 SV=4 8.06 2710.6 - 7.48E+06 - - - -3.7459 - 1.886 0.557 - 274.6 1 2 0 -0.0047 11 0 0 0 4.97E+07 2.05E+08 - - - 4.8699 0.9988 221125_WJC_METTL3_EV_vs_WT_F03.14392.14392.3 3.90E-05 17/52 K.ILIANTGMDTDKIK.L "sp|P78371|TCPB_HUMAN,tr|F8VQ14|F8VQ14_HUMAN,tr|F5GWF6|F5GWF6_HUMAN" 3 1531.828 0.4 30151 14392 3 1531.823037 511.6166 T-complex protein 1 subunit beta OS=Homo sapiens OX=9606 GN=CCT2 PE=1 SV=4 5.96 2710.7 - 1.48E+06 - - - -3.2269 - 2.341 0.439 - 191.3 1 2 1 -0.0049 14 0 0 0 3.68E+08 9.16E+08 - - - 5.6935 0.9989 221125_WJC_METTL3_EV_vs_WT_F03.14394.14394.2 4.01E-05 18-Dec R.DGFGGLAAAR[166.11].G sp|Q96I24|FUBP3_HUMAN 1 943.4751 2.05 30153 14394 2 943.471702 472.7448 Far upstream element-binding protein 3 OS=Homo sapiens OX=9606 GN=FUBP3 PE=1 SV=2 5.84 2710.9 - 1.88E+06 - - - -3.6005 - 2.038 0.452 - 291.4 1 2 0 -0.0034 10 0 0 0 1.30E+09 6.32E+08 - - - 4.3657 0.9998 221125_WJC_METTL3_EV_vs_WT_F03.14398.14398.2 5.50E-05 22-Dec R.ATVVVGDLHPLR.D "sp|Q9NSI2|SLX9_HUMAN,tr|C9JJU7|C9JJU7_HUMAN" 2 1275.7299 1.73 30155 14398 2 1275.729767 638.8722 Ribosome biogenesis protein SLX9 homolog OS=Homo sapiens OX=9606 GN=SLX9 PE=1 SV=2 6.79 2711.4 - 5.34E+06 - - - -0.1199 - 2.357 0.42 - 523.7 1 2 0 -0.0002 12 0 0 0 1.98E+08 1.15E+08 - - - 4.399 0.9992 221125_WJC_METTL3_EV_vs_WT_F03.14399.14399.2 0.000232 18-Dec R.DGFGGLAAAR.G sp|Q96I24|FUBP3_HUMAN 1 933.4668 2.06 30156 14399 2 933.464011 467.7407 Far upstream element-binding protein 3 OS=Homo sapiens OX=9606 GN=FUBP3 PE=1 SV=2 5.84 2711.4 - 4.16E+06 - - - -3.0189 - 1.864 0.474 - 317 1 2 0 -0.0028 10 0 0 0 1.30E+09 6.32E+08 - - - 4.2793 0.9982 221125_WJC_METTL3_EV_vs_WT_F03.14407.14407.2 3.05E-07 15/26 K.ILIANTGMDTDK[136.11]IK[136.11].L "sp|P78371|TCPB_HUMAN,tr|F8VQ14|F8VQ14_HUMAN,tr|F5GWF6|F5GWF6_HUMAN" 3 1547.8564 0.21 30159 14407 2 1547.853738 774.9355 T-complex protein 1 subunit beta OS=Homo sapiens OX=9606 GN=CCT2 PE=1 SV=4 5.96 2712.4 - 3.89E+06 - - - -1.7069 - 2.854 0.518 - 537.4 1 2 1 -0.0026 14 0 0 0 7.00E+07 3.33E+08 - - - 5.4978 0.9993 221125_WJC_METTL3_EV_vs_WT_F03.14410.14410.2 0.00441 16-Sep R.LSESQLSFR.R sp|Q96PK6|RBM14_HUMAN 1 1065.5455 1.76 30160 14410 2 1065.542964 533.78 RNA-binding protein 14 OS=Homo sapiens OX=9606 GN=RBM14 PE=1 SV=2 6 2712.8 - 1.59E+08 - - - -2.3556 - 2.14 0.354 - 353.1 1 2 0 -0.0025 9 0 0 0 7.10E+09 4.03E+09 - - - 3.8559 0.9997 221125_WJC_METTL3_EV_vs_WT_F03.14416.14416.2 9.38E-05 18-Sep R.ELAEDDSILK.- sp|P56385|ATP5I_HUMAN 1 1131.5659 1.93 30162 14416 2 1131.567574 566.7902 "ATP synthase subunit e, mitochondrial OS=Homo sapiens OX=9606 GN=ATP5ME PE=1 SV=2" 3.92 2713.6 - 1.40E+07 - - - 1.4493 - 1.915 0.468 - 298 1 2 0 0.0016 10 0 0 0 4.09E+08 2.12E+08 - - - 4.3107 0.9955 221125_WJC_METTL3_EV_vs_WT_F03.14417.14417.3 0.104 Oct-40 R.NPEAALSPTFR.S "sp|Q86U44|MTA70_HUMAN,tr|B4E349|B4E349_HUMAN,tr|F5H6D8|F5H6D8_HUMAN,tr|B4DTN4|B4DTN4_HUMAN" 4 1201.6091 0.02 30163 14417 3 1201.603381 401.5437 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 6 2713.6 - 8.20E+06 - - - -4.7902 - 2.098 0.315 - 202.1 1 2 0 -0.0058 11 0 0 0 5.08E+08 2.34E+10 - - - 4.1554 0.9937 221125_WJC_METTL3_EV_vs_WT_F03.14419.14419.2 0.00586 13/18 N.PEAALSPTFR[166.11].S "sp|Q86U44|MTA70_HUMAN,tr|B4E349|B4E349_HUMAN,tr|F5H6D8|F5H6D8_HUMAN,tr|B4DTN4|B4DTN4_HUMAN" 4 1097.5745 0.01 30164 14419 2 1097.57492 549.7945 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 6.43 2713.8 - 1.14E+07 - - - 0.4018 - 2.589 0.481 - 820.8 1 1 0 0.0004 10 0 0 0 2.44E+07 1.98E+09 - - - 5.2488 0.9998 221125_WJC_METTL3_EV_vs_WT_F03.14421.14421.2 1.34E-05 20-Sep R.NPEAALSPTFR.S "sp|Q86U44|MTA70_HUMAN,tr|B4E349|B4E349_HUMAN,tr|F5H6D8|F5H6D8_HUMAN,tr|B4DTN4|B4DTN4_HUMAN" 4 1201.6091 0.03 30165 14421 2 1201.607805 601.8118 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 6 2714 - 1.47E+08 - - - -1.1085 - 2.319 0.477 - 403 1 2 0 -0.0013 11 0 0 0 2.53E+10 8.34E+11 - - - 4.8392 0.9996 221125_WJC_METTL3_EV_vs_WT_F03.14423.14423.2 5.44E-05 16-Jul R.VVHIMDFQR[166.11].G "sp|P43243|MATR3_HUMAN,tr|D6RE02|D6RE02_HUMAN,tr|B3KM87|B3KM87_HUMAN,tr|A8MXP9|A8MXP9_HUMAN,tr|D6RAY2|D6RAY2_HUMAN,tr|D6R991|D6R991_HUMAN,tr|A0A0R4J2E8|A0A0R4J2E8_HUMAN,tr|D6RAM9|D6RAM9_HUMAN,tr|D6RIA2|D6RIA2_HUMAN,tr|H0Y8T4|H0Y8T4_HUMAN,tr|D6REM6|D6REM6_HUMAN,tr|D6RBI2|D6RBI2_HUMAN" 12 1153.5942 1.25 30166 14423 2 1153.591671 577.8044 Matrin-3 OS=Homo sapiens OX=9606 GN=MATR3 PE=1 SV=2 6.71 2714.2 - 3.64E+07 - - - -2.1654 - 1.453 0.562 - 175.5 1 2 0 -0.0025 9 0 0 0 3.78E+09 3.03E+09 - - - 4.2721 0.9998 221125_WJC_METTL3_EV_vs_WT_F03.14442.14442.2 0.000163 14-Jul R.DYFEQYGK.L "sp|Q32P51|RA1L2_HUMAN,sp|P09651|ROA1_HUMAN,tr|A0A7I2YQX9|A0A7I2YQX9_HUMAN,tr|F8VZ49|F8VZ49_HUMAN,tr|A0A7I2V3R8|A0A7I2V3R8_HUMAN,tr|F8VTQ5|F8VTQ5_HUMAN,tr|F8W6I7|F8W6I7_HUMAN,tr|A0A7I2V2L6|A0A7I2V2L6_HUMAN,tr|A0A7I2V3W0|A0A7I2V3W0_HUMAN,tr|A0A7I2V5U9|A0A7I2V5U9_HUMAN,tr|A0A2R8Y4L2|A0A2R8Y4L2_HUMAN" 11 1048.4502 1.26 30167 14442 2 1048.450804 525.2324 Heterogeneous nuclear ribonucleoprotein A1-like 2 OS=Homo sapiens OX=9606 GN=HNRNPA1L2 PE=2 SV=2 4.37 2717.4 - 1.01E+07 - - - 0.599 - 1.401 0.563 - 160.7 1 2 0 0.0006 8 0 0 0 2.61E+09 2.07E+09 - - - 4.2161 0.998 221125_WJC_METTL3_EV_vs_WT_F03.14454.14454.2 0.00413 16-Nov R.YQGVNLYVK[136.11].N "sp|Q4VXU2|PAP1L_HUMAN,sp|P11940|PABP1_HUMAN,tr|A0A7I2YQE4|A0A7I2YQE4_HUMAN,tr|A0A6Q8JFT6|A0A6Q8JFT6_HUMAN,tr|H0YAR2|H0YAR2_HUMAN,tr|E7ERJ7|E7ERJ7_HUMAN,tr|A0A7I2YQ88|A0A7I2YQ88_HUMAN,tr|A0A6I8PS38|A0A6I8PS38_HUMAN,tr|A0A6I8PLA1|A0A6I8PLA1_HUMAN,tr|A0A087WTT1|A0A087WTT1_HUMAN,tr|H0YAP2|H0YAP2_HUMAN,tr|A0A7I2V4N4|A0A7I2V4N4_HUMAN,tr|E7EQV3|E7EQV3_HUMAN" 13 1090.5902 1.33 30169 14454 2 1090.586135 546.3024 Polyadenylate-binding protein 1-like OS=Homo sapiens OX=9606 GN=PABPC1L PE=2 SV=1 8.5 2719.2 - 6.63E+06 - - - -3.7695 - 1.717 0.426 - 245.4 1 2 0 -0.0041 9 0 0 0 8.97E+08 6.76E+08 - - - 3.7501 0.9999 221125_WJC_METTL3_EV_vs_WT_F03.14457.14457.2 9.60E-07 20-Sep R.NPEAALSPTFR.S "sp|Q86U44|MTA70_HUMAN,tr|B4E349|B4E349_HUMAN,tr|F5H6D8|F5H6D8_HUMAN,tr|B4DTN4|B4DTN4_HUMAN" 4 1201.6091 0.03 30170 14457 2 1201.608366 601.8118 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 6 2719.6 - 1.72E+08 - - - -0.6416 - 2.287 0.541 - 355.7 1 2 0 -0.0008 11 0 0 0 2.53E+10 8.34E+11 - - - 5.2745 0.9968 221125_WJC_METTL3_EV_vs_WT_F03.14459.14459.2 0.00182 16-Sep R.YQGVNLYVK.N "sp|Q4VXU2|PAP1L_HUMAN,sp|P11940|PABP1_HUMAN,tr|A0A7I2YQE4|A0A7I2YQE4_HUMAN,tr|A0A6Q8JFT6|A0A6Q8JFT6_HUMAN,tr|H0YAR2|H0YAR2_HUMAN,tr|E7ERJ7|E7ERJ7_HUMAN,tr|A0A7I2YQ88|A0A7I2YQ88_HUMAN,tr|A0A6I8PS38|A0A6I8PS38_HUMAN,tr|A0A6I8PLA1|A0A6I8PLA1_HUMAN,tr|A0A087WTT1|A0A087WTT1_HUMAN,tr|H0YAP2|H0YAP2_HUMAN,tr|A0A7I2V4N4|A0A7I2V4N4_HUMAN,tr|E7EQV3|E7EQV3_HUMAN" 13 1082.576 1.33 30171 14459 2 1082.579459 542.2953 Polyadenylate-binding protein 1-like OS=Homo sapiens OX=9606 GN=PABPC1L PE=2 SV=1 8.5 2719.8 - 7.62E+06 - - - 3.1527 - 1.613 0.323 - 152.8 1 2 0 0.0034 9 0 0 0 8.98E+08 6.77E+08 - - - 2.8088 0.9998 221125_WJC_METTL3_EV_vs_WT_F03.14466.14466.2 2.97E-05 13/22 K.FIQSEMSEAVER.A "sp|Q5JSZ5|PRC2B_HUMAN,tr|A0A804HIM8|A0A804HIM8_HUMAN" 2 1424.6606 11.81 30175 14466 2 1424.657723 713.3376 Protein PRRC2B OS=Homo sapiens OX=9606 GN=PRRC2B PE=1 SV=2 4.25 2720.6 - 5.62E+06 - - - -2.0054 - 2.459 0.521 - 321.9 1 2 0 -0.0029 12 0 0 0 1.42E+08 1.20E+07 - - - 5.2556 0.9977 221125_WJC_METTL3_EV_vs_WT_F03.14467.14467.2 0.00794 18-Oct K.QSLPPGLAVK[136.11].E sp|P63173|RL38_HUMAN 1 1016.611 1.51 30176 14467 2 1016.610363 509.3128 60S ribosomal protein L38 OS=Homo sapiens OX=9606 GN=RPL38 PE=1 SV=2 8.75 2720.7 - 4.55E+06 - - - -0.6079 - 1.705 0.162 - 298.9 1 2 0 -0.0006 10 0 0 0 4.71E+08 3.11E+08 - - - 1.7267 0.9947 221125_WJC_METTL3_EV_vs_WT_F03.14473.14473.2 0.726 18-Nov K.QSLPPGLAVK.E sp|P63173|RL38_HUMAN 1 1008.5968 1.48 30178 14473 2 1008.594578 505.3057 60S ribosomal protein L38 OS=Homo sapiens OX=9606 GN=RPL38 PE=1 SV=2 8.75 2721.4 - 4.98E+06 - - - -2.1842 - 1.533 0.202 - 398.7 1 2 0 -0.0022 10 0 0 0 8.69E+08 5.86E+08 - - - 1.7248 0.9996 221125_WJC_METTL3_EV_vs_WT_F03.14475.14475.2 7.42E-06 16-Oct R.VVHIMDFQR.G "sp|P43243|MATR3_HUMAN,tr|D6RE02|D6RE02_HUMAN,tr|B3KM87|B3KM87_HUMAN,tr|A8MXP9|A8MXP9_HUMAN,tr|D6RAY2|D6RAY2_HUMAN,tr|D6R991|D6R991_HUMAN,tr|A0A0R4J2E8|A0A0R4J2E8_HUMAN,tr|D6RAM9|D6RAM9_HUMAN,tr|D6RIA2|D6RIA2_HUMAN,tr|H0Y8T4|H0Y8T4_HUMAN,tr|D6REM6|D6REM6_HUMAN,tr|D6RBI2|D6RBI2_HUMAN" 12 1143.5859 1.21 30179 14475 2 1143.583178 572.8002 Matrin-3 OS=Homo sapiens OX=9606 GN=MATR3 PE=1 SV=2 6.71 2721.7 - 3.31E+07 - - - -2.3794 - 1.701 0.568 - 437.5 1 2 0 -0.0027 9 0 0 0 3.63E+09 2.99E+09 - - - 4.7722 0.9936 221125_WJC_METTL3_EV_vs_WT_F03.14481.14481.2 6.77E-07 13/24 R.AQAALAVNISAAR.G sp|P40227|TCPZ_HUMAN 1 1254.7044 0.5 30180 14481 2 1254.695587 628.3595 T-complex protein 1 subunit zeta OS=Homo sapiens OX=9606 GN=CCT6A PE=1 SV=3 9.79 2722.6 - 6.18E+06 - - - -7.0511 - 2.653 0.565 - 673.9 1 2 0 -0.0088 13 0 0 0 5.45E+08 1.08E+09 - - - 5.7155 0.9966 221125_WJC_METTL3_EV_vs_WT_F03.14497.14497.2 0.000742 22-Sep R.VVDALGNAIDGK[136.11].G "sp|P25705|ATPA_HUMAN,tr|K7EQH4|K7EQH4_HUMAN,tr|K7ERX7|K7ERX7_HUMAN,tr|K7EK77|K7EK77_HUMAN,tr|K7EJP1|K7EJP1_HUMAN,tr|K7ENJ4|K7ENJ4_HUMAN" 6 1178.6387 1.59 30184 14497 2 1178.633464 590.3266 "ATP synthase subunit alpha, mitochondrial OS=Homo sapiens OX=9606 GN=ATP5F1A PE=1 SV=1" 4.21 2724.8 - 1.26E+07 - - - -4.4017 - 1.711 0.437 - 133.8 1 2 0 -0.0052 12 0 0 0 1.47E+09 9.29E+08 - - - 3.6802 0.9998 221125_WJC_METTL3_EV_vs_WT_F03.14502.14502.2 8.90E-08 20/28 K.IEDLSQQAQLAAAEK[136.11].F "sp|E9PAV3|NACAM_HUMAN,sp|Q13765|NACA_HUMAN,tr|A0A7I2V473|A0A7I2V473_HUMAN,tr|F8VZJ2|F8VZJ2_HUMAN,tr|F8VNW4|F8VNW4_HUMAN,tr|A0A7I2V2K5|A0A7I2V2K5_HUMAN,tr|F8W0W4|F8W0W4_HUMAN,tr|H0YHX9|H0YHX9_HUMAN" 8 1621.8403 0.34 30186 14502 2 1621.837207 811.9274 "Nascent polypeptide-associated complex subunit alpha, muscle-specific form OS=Homo sapiens OX=9606 GN=NACA PE=1 SV=1" 4.14 2725.4 - 6.19E+06 - - - -1.8855 - 3.511 0.461 - 1251.2 1 2 0 -0.0031 15 0 0 0 8.83E+07 2.57E+08 - - - 5.5327 0.9992 221125_WJC_METTL3_EV_vs_WT_F03.14512.14512.2 0.00217 18-Sep R.TSGSVYITLK[136.11].K "sp|P37108|SRP14_HUMAN,tr|H0YLA2|H0YLA2_HUMAN" 2 1075.6005 0.87 30190 14512 2 1075.59837 538.8075 Signal recognition particle 14 kDa protein OS=Homo sapiens OX=9606 GN=SRP14 PE=1 SV=2 8.26 2726.7 - 4.98E+06 - - - -1.958 - 1.647 0.395 - 216.1 1 2 0 -0.0021 10 0 0 0 2.79E+08 3.19E+08 - - - 3.3505 0.9998 221125_WJC_METTL3_EV_vs_WT_F03.14516.14516.2 6.69E-06 14/24 R.LSDSIAATSELER.K "sp|Q15643|TRIPB_HUMAN,tr|H0YJ97|H0YJ97_HUMAN" 2 1390.694 1.39 30192 14516 2 1390.695169 696.3543 Thyroid receptor-interacting protein 11 OS=Homo sapiens OX=9606 GN=TRIP11 PE=1 SV=3 4.14 2727.1 - 6.81E+06 - - - 0.8485 - 2.936 0.391 - 617.9 1 2 0 0.0012 13 0 0 0 4.20E+08 3.02E+08 - - - 4.6928 0.9978 221125_WJC_METTL3_EV_vs_WT_F03.14524.14524.2 0.0193 14-Jul R.SLFEQYGK[136.11].V "sp|Q9BWF3|RBM4_HUMAN,sp|Q9BQ04|RBM4B_HUMAN,tr|E9PM61|E9PM61_HUMAN,tr|D6R9K7|D6R9K7_HUMAN,tr|J3QRR5|J3QRR5_HUMAN,tr|E9PB51|E9PB51_HUMAN,tr|U3KQD5|U3KQD5_HUMAN,tr|E9PLB0|E9PLB0_HUMAN" 8 978.4902 1.3 30195 14524 2 978.490841 490.2524 RNA-binding protein 4 OS=Homo sapiens OX=9606 GN=RBM4 PE=1 SV=1 5.72 2728.1 - 6.20E+06 - - - 0.6582 - 1.209 0.301 - 143.1 1 2 0 0.0006 8 0 0 0 1.69E+09 1.30E+09 - - - 1.8364 0.9901 221125_WJC_METTL3_EV_vs_WT_F03.14528.14528.2 0.149 14-Jul R.SLFEQYGK.V "sp|Q9BWF3|RBM4_HUMAN,sp|Q9BQ04|RBM4B_HUMAN,tr|E9PM61|E9PM61_HUMAN,tr|D6R9K7|D6R9K7_HUMAN,tr|J3QRR5|J3QRR5_HUMAN,tr|E9PB51|E9PB51_HUMAN,tr|U3KQD5|U3KQD5_HUMAN,tr|E9PLB0|E9PLB0_HUMAN" 8 970.476 1.25 30198 14528 2 970.476944 486.2453 RNA-binding protein 4 OS=Homo sapiens OX=9606 GN=RBM4 PE=1 SV=1 5.72 2728.4 - 6.23E+06 - - - 0.9758 - 1.121 0.193 - 143 1 2 0 0.0009 8 0 0 0 1.69E+09 1.36E+09 - - - 0.8107 0.9992 221125_WJC_METTL3_EV_vs_WT_F03.14530.14530.2 7.07E-08 17/24 R.LSDSIAATSELER[166.11].K "sp|Q15643|TRIPB_HUMAN,tr|H0YJ97|H0YJ97_HUMAN" 2 1400.7023 1.39 30199 14530 2 1400.69679 701.3584 Thyroid receptor-interacting protein 11 OS=Homo sapiens OX=9606 GN=TRIP11 PE=1 SV=3 4.14 2728.6 - 1.02E+07 - - - -3.9045 - 3.188 0.446 - 984.7 1 2 0 -0.0055 13 0 0 0 4.20E+08 3.02E+08 - - - 5.3091 0.9998 221125_WJC_METTL3_EV_vs_WT_F03.14534.14534.2 1.68E-05 18-Nov R.TSGSVYITLK.K "sp|P37108|SRP14_HUMAN,tr|H0YLA2|H0YLA2_HUMAN" 2 1067.5863 0.88 30200 14534 2 1067.584333 534.8004 Signal recognition particle 14 kDa protein OS=Homo sapiens OX=9606 GN=SRP14 PE=1 SV=2 8.26 2729.2 - 6.68E+06 - - - -1.82 - 2.104 0.51 - 447.4 1 2 0 -0.0019 10 0 0 0 2.80E+08 3.20E+08 - - - 4.8835 0.9993 221125_WJC_METTL3_EV_vs_WT_F03.14539.14539.2 0.228 16-Oct R.IQSLPDLSR.L "sp|Q96P16|RPR1A_HUMAN,tr|K7ER50|K7ER50_HUMAN" 2 1027.5662 1.5 30202 14539 2 1027.566206 514.7904 Regulation of nuclear pre-mRNA domain-containing protein 1A OS=Homo sapiens OX=9606 GN=RPRD1A PE=1 SV=1 5.84 2729.9 - 3.39E+06 - - - -0.0029 - 2.043 0.212 - 332 1 2 0 0 9 0 0 0 1.73E+08 1.15E+08 - - - 2.6737 0.9735 221125_WJC_METTL3_EV_vs_WT_F03.14544.14544.2 0.0578 16-Oct R.ANEFLEVGK[136.11].K sp|Q14152|EIF3A_HUMAN 1 1013.5273 0.92 30204 14544 2 1013.520588 507.7709 Eukaryotic translation initiation factor 3 subunit A OS=Homo sapiens OX=9606 GN=EIF3A PE=1 SV=1 4.53 2730.5 - 2.70E+06 - - - -6.6333 - 1.986 0.284 - 477.9 1 2 0 -0.0067 9 0 0 0 1.04E+08 1.13E+08 - - - 3.1215 0.9992 221125_WJC_METTL3_EV_vs_WT_F03.14546.14546.2 0.0113 16-Oct R.IQSLPDLSR[166.11].L "sp|Q96P16|RPR1A_HUMAN,tr|K7ER50|K7ER50_HUMAN" 2 1037.5745 1.5 30205 14546 2 1037.573243 519.7945 Regulation of nuclear pre-mRNA domain-containing protein 1A OS=Homo sapiens OX=9606 GN=RPRD1A PE=1 SV=1 5.84 2730.7 - 3.85E+06 - - - -1.1912 - 1.98 0.247 - 302.7 1 2 0 -0.0012 9 0 0 0 1.73E+08 1.16E+08 - - - 2.8412 0.9998 221125_WJC_METTL3_EV_vs_WT_F03.14547.14547.2 9.65E-05 20-Nov K.EVLSMDDEIQK[136.11].L "sp|Q06210|GFPT1_HUMAN,tr|A0A6I8PRN4|A0A6I8PRN4_HUMAN,tr|A0A6I8PTT9|A0A6I8PTT9_HUMAN" 3 1313.6264 1.74 30206 14547 2 1313.624127 657.8205 Glutamine--fructose-6-phosphate aminotransferase [isomerizing] 1 OS=Homo sapiens OX=9606 GN=GFPT1 PE=1 SV=3 3.92 2730.8 - 0 - - - -1.7554 - 2.225 0.509 - 327.3 1 2 0 -0.0023 11 0 0 0 7.58E+07 4.36E+07 - - - 4.9633 0.9988 221125_WJC_METTL3_EV_vs_WT_F03.14548.14548.2 2.35E-06 20-Dec K.NQMLIEEEVQK.L "sp|Q9Y5K5|UCHL5_HUMAN,tr|H0Y4K0|H0Y4K0_HUMAN,tr|H0Y4E0|H0Y4E0_HUMAN,tr|Q5LJA9|Q5LJA9_HUMAN,tr|H0Y636|H0Y636_HUMAN,tr|H0Y6Y4|H0Y6Y4_HUMAN,tr|Q5LJA5|Q5LJA5_HUMAN" 7 1359.6704 14.29 30207 14548 2 1359.664368 680.8425 Ubiquitin carboxyl-terminal hydrolase isozyme L5 OS=Homo sapiens OX=9606 GN=UCHL5 PE=1 SV=3 4.25 2730.9 - 3.45E+06 - - - -4.4481 - 2.511 0.516 - 513.2 1 2 0 -0.006 11 0 0 0 1.76E+08 1.23E+07 - - - 5.3409 0.9993 221125_WJC_METTL3_EV_vs_WT_F03.14553.14553.2 0.00529 20-Oct K.LTAEAIQTPLK.S sp|Q53HL2|BOREA_HUMAN 1 1183.6812 1.78 30209 14553 2 1183.678244 592.8479 Borealin OS=Homo sapiens OX=9606 GN=CDCA8 PE=1 SV=2 6 2731.5 - 0 - - - -2.5302 - 2.155 0.389 - 198.8 1 2 0 -0.003 11 0 0 0 1.10E+08 6.16E+07 - - - 3.9903 0.9954 221125_WJC_METTL3_EV_vs_WT_F03.14554.14554.2 0.339 14-Aug K.DISLSDYK[136.11].G "sp|Q06830|PRDX1_HUMAN,tr|A0A0A0MSI0|A0A0A0MSI0_HUMAN" 2 947.4691 0.69 30210 14554 2 947.465841 474.7418 Peroxiredoxin-1 OS=Homo sapiens OX=9606 GN=PRDX1 PE=1 SV=1 4.21 2731.6 - 2.38E+06 - - - -3.4682 - 1.618 0.293 - 178.4 1 2 0 -0.0033 8 0 0 0 4.64E+08 6.74E+08 - - - 2.6553 0.9991 221125_WJC_METTL3_EV_vs_WT_F03.14558.14558.2 0.00382 16-Sep K.GVQYLNEIK[136.11].D sp|P13639|EF2_HUMAN 1 1070.5852 0.55 30212 14558 2 1070.584887 536.2999 Elongation factor 2 OS=Homo sapiens OX=9606 GN=EEF2 PE=1 SV=4 6 2732 - 5.39E+06 - - - -0.255 - 1.538 0.291 - 182.5 1 2 0 -0.0003 9 0 0 0 9.87E+07 1.79E+08 - - - 2.4357 0.999 221125_WJC_METTL3_EV_vs_WT_F03.14560.14560.2 0.0266 12-Sep K.C[160.03]DWLDGK.H "sp|O43447|PPIH_HUMAN,tr|H0YEL5|H0YEL5_HUMAN,tr|A0A7I2YQS4|A0A7I2YQS4_HUMAN,tr|C9JQD4|C9JQD4_HUMAN" 4 892.3749 2.94 30214 14560 2 892.371568 447.1947 Peptidyl-prolyl cis-trans isomerase H OS=Homo sapiens OX=9606 GN=PPIH PE=1 SV=1 4.21 2732.2 - 3.72E+06 - - - -3.7372 - 1.782 0.512 - 487.7 1 2 0 -0.0033 7 0 0 0 1.10E+08 3.72E+07 - - - 4.6522 0.9896 221125_WJC_METTL3_EV_vs_WT_F03.14566.14566.2 0.243 14-Sep K.DGLILTSR.G "sp|Q99497|PARK7_HUMAN,tr|K7EN27|K7EN27_HUMAN,tr|K7ELW0|K7ELW0_HUMAN" 3 873.492 3.56 30218 14566 2 873.490018 437.7533 Parkinson disease protein 7 OS=Homo sapiens OX=9606 GN=PARK7 PE=1 SV=2 5.84 2733 - 3.05E+06 - - - -2.2484 - 1.548 0.121 - 254.5 1 2 0 -0.002 8 0 0 0 4.95E+07 1.39E+07 - - - 1.252 0.9999 221125_WJC_METTL3_EV_vs_WT_F03.14570.14570.3 0.000224 14/44 K.IEVEK[136.11]PFAIAK[136.11]E.- "sp|P23284|PPIB_HUMAN,tr|A0A7P0Z497|A0A7P0Z497_HUMAN,tr|A0A7P0TB45|A0A7P0TB45_HUMAN" 3 1388.7886 0.34 30220 14570 3 1388.787533 463.9368 Peptidyl-prolyl cis-trans isomerase B OS=Homo sapiens OX=9606 GN=PPIB PE=1 SV=2 5.01 2733.5 - 2.33E+06 - - - -0.7813 - 2.406 0.363 - 151 1 2 0 -0.0011 12 0 0 0 2.40E+07 7.08E+07 - - - 5.0204 0.9994 221125_WJC_METTL3_EV_vs_WT_F03.14571.14571.2 0.00373 20-Oct R.LNIPVSQVNPR[166.11].D "sp|P05023|AT1A1_HUMAN,sp|P13637|AT1A3_HUMAN,tr|A0A0A0MT26|A0A0A0MT26_HUMAN,tr|A0A2R8YEY8|A0A2R8YEY8_HUMAN,tr|M0R116|M0R116_HUMAN" 5 1245.7069 1.3 30221 14571 2 1245.709372 623.8607 Sodium\potassium-transporting ATPase subunit alpha-1 OS=Homo sapiens OX=9606 GN=ATP1A1 PE=1 SV=1 9.75 2733.6 - 3.80E+06 - - - 1.9924 - 2.006 0.395 - 381 1 2 0 0.0025 11 0 0 0 1.55E+08 1.20E+08 - - - 3.8409 0.9988 221125_WJC_METTL3_EV_vs_WT_F03.14572.14572.2 0.0523 14-Sep K.DISLSDYK.G "sp|Q06830|PRDX1_HUMAN,tr|A0A0A0MSI0|A0A0A0MSI0_HUMAN" 2 939.4549 0.69 30222 14572 2 939.453129 470.7347 Peroxiredoxin-1 OS=Homo sapiens OX=9606 GN=PRDX1 PE=1 SV=1 4.21 2733.6 - 6.95E+06 - - - -1.9139 - 1.703 0.295 - 221.1 1 2 0 -0.0018 8 0 0 0 4.65E+08 6.75E+08 - - - 2.825 1 221125_WJC_METTL3_EV_vs_WT_F03.14576.14576.2 3.27E-07 20-Dec R.NPEAALSPTFR[166.11].S "sp|Q86U44|MTA70_HUMAN,tr|B4E349|B4E349_HUMAN,tr|F5H6D8|F5H6D8_HUMAN,tr|B4DTN4|B4DTN4_HUMAN" 4 1211.6174 0.03 30224 14576 2 1211.617495 606.816 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 6 2734.1 - 2.95E+09 - - - 0.0726 - 2.601 0.584 - 747.4 1 2 0 0.0001 11 0 0 0 2.54E+10 8.34E+11 - - - 5.9403 0.9943 221125_WJC_METTL3_EV_vs_WT_F03.14577.14577.2 0.0566 16-Oct R.ANEFLEVGK.K sp|Q14152|EIF3A_HUMAN 1 1005.5131 0.92 30225 14577 2 1005.508468 503.7638 Eukaryotic translation initiation factor 3 subunit A OS=Homo sapiens OX=9606 GN=EIF3A PE=1 SV=1 4.53 2734.2 - 5.02E+06 - - - -4.6175 - 2.041 0.295 - 652.4 1 2 0 -0.0046 9 0 0 0 1.04E+08 1.13E+08 - - - 3.2824 0.9989 221125_WJC_METTL3_EV_vs_WT_F03.14578.14578.2 0.00727 14-Sep K.DAQIFIQK.K sp|P04040|CATA_HUMAN 1 961.5233 5.04 30226 14578 2 961.521081 481.7689 Catalase OS=Homo sapiens OX=9606 GN=CAT PE=1 SV=3 5.84 2734.3 - 9.96E+06 - - - -2.2891 - 1.853 0.316 - 371.6 1 2 0 -0.0022 8 0 0 0 2.77E+08 5.50E+07 - - - 3.2345 0.9997 221125_WJC_METTL3_EV_vs_WT_F03.14581.14581.2 5.92E-05 18-Nov R.QYDIDDAIAK.N "sp|Q15149|PLEC_HUMAN,tr|H0YDN1|H0YDN1_HUMAN" 2 1150.5506 9.11 30229 14581 2 1150.549457 576.2826 Plectin OS=Homo sapiens OX=9606 GN=PLEC PE=1 SV=3 3.93 2734.6 - 1.83E+06 - - - -1.01 - 1.986 0.398 - 415.8 1 2 0 -0.0012 10 0 0 0 4.31E+07 4.73E+06 - - - 3.8954 0.9906 221125_WJC_METTL3_EV_vs_WT_F03.14586.14586.2 0.0249 14-Aug K.TIIGDFQK[136.11].E sp|Q96A49|SYAP1_HUMAN 1 928.5109 1.19 30232 14586 2 928.507942 465.2627 Synapse-associated protein 1 OS=Homo sapiens OX=9606 GN=SYAP1 PE=1 SV=1 5.5 2735.1 - 5.36E+06 - - - -3.2213 - 1.26 0.289 - 171.5 1 2 0 -0.003 8 0 0 0 3.96E+09 3.32E+09 - - - 1.8716 0.9997 221125_WJC_METTL3_EV_vs_WT_F03.14588.14588.2 5.00E-05 24-Oct R.NVGFESDTGGAFK.G "sp|Q9UKX7|NUP50_HUMAN,tr|B0QY21|B0QY21_HUMAN" 2 1327.6044 1.96 30234 14588 2 1327.607514 664.8095 Nuclear pore complex protein Nup50 OS=Homo sapiens OX=9606 GN=NUP50 PE=1 SV=2 4.37 2735.3 - 3.76E+06 - - - 2.3117 - 2.245 0.588 - 186.6 1 2 0 0.0031 13 0 0 0 1.10E+08 5.61E+07 - - - 5.4586 0.9971 221125_WJC_METTL3_EV_vs_WT_F03.14590.14590.2 0.00015 18-Sep K.ISTQLDFASK.R sp|P12270|TPR_HUMAN 1 1108.5764 3.3 30236 14590 2 1108.571274 555.2955 Nucleoprotein TPR OS=Homo sapiens OX=9606 GN=TPR PE=1 SV=3 5.84 2735.4 - 1.81E+06 - - - -4.66 - 2.064 0.414 - 189.5 1 2 0 -0.0052 10 0 0 0 1.31E+08 3.97E+07 - - - 4.1199 0.9999 221125_WJC_METTL3_EV_vs_WT_F03.14592.14592.3 0.000232 Nov-40 R.NPEAALSPTFR[166.11].S "sp|Q86U44|MTA70_HUMAN,tr|B4E349|B4E349_HUMAN,tr|F5H6D8|F5H6D8_HUMAN,tr|B4DTN4|B4DTN4_HUMAN" 4 1211.6174 0.02 30237 14592 3 1211.614974 404.8797 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 6 2735.7 - 1.18E+08 - - - -2.0081 - 2.367 0.429 - 287.5 1 2 0 -0.0024 11 0 0 0 9.45E+08 4.02E+10 - - - 5.77 0.9988 221125_WJC_METTL3_EV_vs_WT_F03.14595.14595.2 0.0502 14-Aug K.TIIGDFQK.E sp|Q96A49|SYAP1_HUMAN 1 920.4967 1.19 30239 14595 2 920.495694 461.2556 Synapse-associated protein 1 OS=Homo sapiens OX=9606 GN=SYAP1 PE=1 SV=1 5.5 2735.9 - 6.07E+06 - - - -1.1287 - 1.428 0.309 - 156.2 1 2 0 -0.001 8 0 0 0 3.96E+09 3.32E+09 - - - 2.3975 1 221125_WJC_METTL3_EV_vs_WT_F03.14596.14596.2 1.50E-09 13/24 R.NVGFESDTGGAFK[136.11].G "sp|Q9UKX7|NUP50_HUMAN,tr|B0QY21|B0QY21_HUMAN" 2 1335.6186 1.96 30240 14596 2 1335.607513 668.8166 Nuclear pore complex protein Nup50 OS=Homo sapiens OX=9606 GN=NUP50 PE=1 SV=2 4.37 2736.1 - 2.45E+06 - - - -8.3347 - 2.631 0.701 - 384.8 1 2 0 -0.0111 13 0 0 0 1.09E+08 5.57E+07 - - - 6.6979 0.995 221125_WJC_METTL3_EV_vs_WT_F03.14600.14600.3 0.318 Sep-48 K.LLNAYDEHQTLLK[136.11].E sp|Q86UA1|PRP39_HUMAN 1 1564.8341 1.31 30244 14600 3 1564.831344 522.6186 Pre-mRNA-processing factor 39 OS=Homo sapiens OX=9606 GN=PRPF39 PE=1 SV=3 5.32 2736.6 - 1.54E+06 - - - -1.7344 - 1.607 0.239 - 80.9 1 2 0 -0.0027 13 0 0 0 1.62E+07 1.24E+07 - - - 2.49 0.9995 221125_WJC_METTL3_EV_vs_WT_F03.14601.14601.2 0.000826 12-Aug K.C[160.03]DWLDGK[136.11].H "sp|O43447|PPIH_HUMAN,tr|H0YEL5|H0YEL5_HUMAN,tr|A0A7I2YQS4|A0A7I2YQS4_HUMAN,tr|C9JQD4|C9JQD4_HUMAN" 4 900.3891 2.94 30245 14601 2 900.386946 451.2018 Peptidyl-prolyl cis-trans isomerase H OS=Homo sapiens OX=9606 GN=PPIH PE=1 SV=1 4.21 2736.7 - 1.30E+06 - - - -2.3956 - 1.559 0.521 - 323.9 1 2 0 -0.0022 7 0 0 0 1.10E+08 3.72E+07 - - - 4.2954 0.9999 221125_WJC_METTL3_EV_vs_WT_F03.14605.14605.2 0.000124 13/18 R.TFLQTVSSEK[136.11].V sp|Q96EL3|RM53_HUMAN 1 1146.6012 1.27 30248 14605 2 1146.601185 574.3079 "39S ribosomal protein L53, mitochondrial OS=Homo sapiens OX=9606 GN=MRPL53 PE=1 SV=1" 5.66 2737 - 6.08E+06 - - - -0.0166 - 2.412 0.509 - 455.9 1 2 0 0 10 0 0 0 3.33E+08 2.62E+08 - - - 5.2581 0.9964 221125_WJC_METTL3_EV_vs_WT_F03.14607.14607.3 0.0378 Nov-44 K.IEVEKPFAIAKE.- "sp|P23284|PPIB_HUMAN,tr|A0A7P0Z497|A0A7P0Z497_HUMAN,tr|A0A7P0TB45|A0A7P0TB45_HUMAN" 3 1372.7602 0.34 30250 14607 3 1372.761303 458.594 Peptidyl-prolyl cis-trans isomerase B OS=Homo sapiens OX=9606 GN=PPIB PE=1 SV=2 5.01 2737.3 - 1.60E+06 - - - 0.7904 - 1.906 0.19 - 94.8 1 2 0 0.0011 12 0 0 0 2.40E+07 7.10E+07 - - - 2.4459 0.9963 221125_WJC_METTL3_EV_vs_WT_F03.14608.14608.2 0.0601 20-Aug K.IFDPQNPDENE.- sp|P46109|CRKL_HUMAN 1 1316.5521 - 30251 14608 2 1316.553344 659.2833 Crk-like protein OS=Homo sapiens OX=9606 GN=CRKL PE=1 SV=1 3.7 2737.4 - 1.17E+06 - - - 0.9639 - 1.449 0.199 - 190.3 1 2 0 0.0013 11 0 0 0 - - - - - 1.5137 0.9978 221125_WJC_METTL3_EV_vs_WT_F03.14609.14609.2 0.177 18-Aug K.SFLYPGSSTR.K "sp|Q9NZJ0|DTL_HUMAN,tr|F5GZ90|F5GZ90_HUMAN" 2 1113.5455 0.39 30252 14609 2 1113.543941 557.78 Denticleless protein homolog OS=Homo sapiens OX=9606 GN=DTL PE=1 SV=3 8.46 2737.5 - 1.05E+06 - - - -1.3767 - 1.661 0.21 - 216.1 1 2 0 -0.0015 10 0 0 0 1.06E+07 2.68E+07 - - - 2.0079 0.9999 221125_WJC_METTL3_EV_vs_WT_F03.14612.14612.2 6.57E-06 18-Nov R.TFLQTVSSEK.V sp|Q96EL3|RM53_HUMAN 1 1138.587 1.28 30253 14612 2 1138.585621 570.3008 "39S ribosomal protein L53, mitochondrial OS=Homo sapiens OX=9606 GN=MRPL53 PE=1 SV=1" 5.66 2737.9 - 7.73E+06 - - - -1.2147 - 2.268 0.495 - 352.8 1 2 0 -0.0014 10 0 0 0 3.35E+08 2.62E+08 - - - 4.9824 0.9999 221125_WJC_METTL3_EV_vs_WT_F03.14616.14616.3 0.000647 13/40 R.AVFPSIVGRPR.Q "sp|Q6S8J3|POTEE_HUMAN,sp|P63261|ACTG_HUMAN,sp|P68133|ACTS_HUMAN,sp|P62736|ACTA_HUMAN,sp|Q9BYX7|ACTBM_HUMAN,sp|P68032|ACTC_HUMAN,sp|P60709|ACTB_HUMAN,sp|P63267|ACTH_HUMAN,sp|A5A3E0|POTEF_HUMAN,sp|P0CG38|POTEI_HUMAN,tr|A0A804GS07|A0A804GS07_HUMAN,tr|I3L3I0|I3L3I0_HUMAN,tr|G5E9R0|G5E9R0_HUMAN,tr|E7EVS6|E7EVS6_HUMAN,tr|B8ZZJ2|B8ZZJ2_HUMAN,tr|J3KT65|J3KT65_HUMAN,tr|I3L3R2|I3L3R2_HUMAN,tr|K7EM38|K7EM38_HUMAN,tr|F6QUT6|F6QUT6_HUMAN,tr|C9JTX5|C9JTX5_HUMAN,tr|A0A6Q8PH58|A0A6Q8PH58_HUMAN,tr|F6UVQ4|F6UVQ4_HUMAN,tr|F8WB63|F8WB63_HUMAN,tr|I3L1U9|I3L1U9_HUMAN,tr|A0A2R8Y793|A0A2R8Y793_HUMAN,tr|I3L4N8|I3L4N8_HUMAN,tr|C9JUM1|C9JUM1_HUMAN,tr|F8WCH0|F8WCH0_HUMAN,tr|C9JZR7|C9JZR7_HUMAN,tr|C9JFL5|C9JFL5_HUMAN,tr|A0A2R8YGF8|A0A2R8YGF8_HUMAN,tr|A6NL76|A6NL76_HUMAN" 32 1197.6982 0.95 30256 14616 3 1197.699684 400.24 POTE ankyrin domain family member E OS=Homo sapiens OX=9606 GN=POTEE PE=2 SV=3 12 2738.3 - 7.12E+06 - - - 1.2173 - 2.028 0.444 - 287.5 1 2 0 0.0015 11 0 0 0 1.78E+09 1.88E+09 - - - 5.4984 0.9976 221125_WJC_METTL3_EV_vs_WT_F03.14617.14617.2 0.0435 20-Aug R.LNIPVSQVNPR.D "sp|P05023|AT1A1_HUMAN,sp|P13637|AT1A3_HUMAN,tr|A0A0A0MT26|A0A0A0MT26_HUMAN,tr|A0A2R8YEY8|A0A2R8YEY8_HUMAN,tr|M0R116|M0R116_HUMAN" 5 1235.6986 1.29 30257 14617 2 1235.695971 618.8566 Sodium\potassium-transporting ATPase subunit alpha-1 OS=Homo sapiens OX=9606 GN=ATP1A1 PE=1 SV=1 9.75 2738.3 - 6.94E+06 - - - -2.1437 - 1.437 0.316 - 154 1 2 0 -0.0027 11 0 0 0 1.55E+08 1.20E+08 - - - 2.3549 0.9989 221125_WJC_METTL3_EV_vs_WT_F03.14618.14618.2 7.24E-09 13/24 R.FSGSGSGTDFTLK.L "sp|A2NJV5|KV229_HUMAN,sp|A0A087WW87|KV240_HUMAN,sp|P06310|KV230_HUMAN,sp|A0A075B6S2|KVD29_HUMAN,sp|P01614|KVD40_HUMAN,sp|P01615|KVD28_HUMAN,sp|A0A075B6S6|KVD30_HUMAN,sp|A0A075B6P5|KV228_HUMAN,sp|A0A0A0MRZ7|KVD26_HUMAN" 9 1302.6092 1140 30258 14618 2 1302.603387 652.3119 Immunoglobulin kappa variable 2-29 OS=Homo sapiens OX=9606 GN=IGKV2-29 PE=3 SV=2 5.84 2738.5 - 1.70E+06 - - - -4.4595 - 2.606 0.549 - 329.4 1 2 0 -0.0058 13 0 0 0 7.78E+09 6.83E+06 - - - 5.5524 0.9999 221125_WJC_METTL3_EV_vs_WT_F03.14619.14619.2 1.24E-09 19/30 K.AGAGSATLSMAYAGAR.F "sp|P40926|MDHM_HUMAN,tr|G3XAL0|G3XAL0_HUMAN" 2 1453.6984 1.73 30259 14619 2 1453.696127 727.8565 "Malate dehydrogenase, mitochondrial OS=Homo sapiens OX=9606 GN=MDH2 PE=1 SV=3" 8.79 2738.6 - 1.42E+06 - - - -1.5375 - 3.766 0.444 - 1240.9 1 2 0 -0.0022 16 0 0 0 2.11E+07 1.22E+07 - - - 5.5797 0.9973 221125_WJC_METTL3_EV_vs_WT_F03.14621.14621.2 0.00565 12-Jul K.FC[160.03]FPC[160.03]SR[166.11].Q "sp|Q7Z5L9|I2BP2_HUMAN,sp|Q8IU81|I2BP1_HUMAN,sp|Q9H1B7|I2BPL_HUMAN" 3 982.4029 1.34 30261 14621 2 982.405006 492.2087 Interferon regulatory factor 2-binding protein 2 OS=Homo sapiens OX=9606 GN=IRF2BP2 PE=1 SV=2 8.07 2738.8 - 4.03E+06 - - - 2.1814 - 1.341 0.32 - 175.4 1 2 0 0.0021 7 0 0 0 9.91E+07 7.40E+07 - - - 2.3336 0.9975 221125_WJC_METTL3_EV_vs_WT_F03.14625.14625.3 0.00101 14/44 K.FAASGGFLHHMA.G "sp|Q9BY77|PDIP3_HUMAN,tr|F6VRR5|F6VRR5_HUMAN,tr|F8WCX5|F8WCX5_HUMAN,tr|Q8WUT1|Q8WUT1_HUMAN" 4 1244.5761 - 30263 14625 3 1244.574494 415.866 Polymerase delta-interacting protein 3 OS=Homo sapiens OX=9606 GN=POLDIP3 PE=1 SV=2 6.92 2739.2 - 2.64E+06 - - - -1.2599 - 2.631 0.518 - 127.7 1 1 0 -0.0016 12 0 0 0 - - - - - 6.9961 0.9996 221125_WJC_METTL3_EV_vs_WT_F03.14626.14626.2 7.26E-05 18-Sep K.ISTQLDFASK[136.11].R sp|P12270|TPR_HUMAN 1 1116.5906 3.25 30264 14626 2 1116.592285 559.3026 Nucleoprotein TPR OS=Homo sapiens OX=9606 GN=TPR PE=1 SV=3 5.84 2739.3 - 2.08E+06 - - - 1.4732 - 2.221 0.345 - 196.9 1 2 0 0.0016 10 0 0 0 1.29E+08 3.97E+07 - - - 3.816 0.9984 221125_WJC_METTL3_EV_vs_WT_F03.14628.14628.2 2.08E-07 16/30 K.AGAGSATLSMAYAGAR[166.11].F "sp|P40926|MDHM_HUMAN,tr|G3XAL0|G3XAL0_HUMAN" 2 1463.7066 1.73 30266 14628 2 1463.700731 732.8606 "Malate dehydrogenase, mitochondrial OS=Homo sapiens OX=9606 GN=MDH2 PE=1 SV=3" 8.79 2739.5 - 1.31E+06 - - - -4.0315 - 3.264 0.323 - 505.7 1 2 0 -0.0059 16 0 0 0 2.11E+07 1.22E+07 - - - 4.3332 0.9998 221125_WJC_METTL3_EV_vs_WT_F03.14629.14629.2 2.07E-07 20-Dec K.TPYIVLSGSGK[136.11].S sp|O43290|SNUT1_HUMAN 1 1128.627 2.37 30267 14629 2 1128.627304 565.3208 U4\U6.U5 tri-snRNP-associated protein 1 OS=Homo sapiens OX=9606 GN=SART1 PE=1 SV=1 8.26 2739.6 - 1.08E+06 - - - 0.2472 - 2.493 0.398 - 530 1 2 0 0.0003 11 0 0 0 9.19E+07 3.88E+07 - - - 4.4517 0.9977 221125_WJC_METTL3_EV_vs_WT_F03.14631.14631.2 0.826 22-Jul R.FLEQQNQVLETK.W "sp|Q86Y46|K2C73_HUMAN,sp|Q7RTS7|K2C74_HUMAN,sp|Q3SY84|K2C71_HUMAN,sp|Q14CN4|K2C72_HUMAN,tr|H0YIG3|H0YIG3_HUMAN,tr|F8W1S1|F8W1S1_HUMAN" 6 1475.762 14.92 30269 14631 2 1475.760101 738.8883 "Keratin, type II cytoskeletal 73 OS=Homo sapiens OX=9606 GN=KRT73 PE=1 SV=1" 4.53 2739.9 - 804276 - - - -1.2929 - 1.325 0.291 - 96.7 1 2 0 -0.0019 12 0 0 0 2.87E+07 1.92E+06 - - - 1.9302 0.9998 221125_WJC_METTL3_EV_vs_WT_F03.14632.14632.2 3.96E-06 24-Oct K.C[160.03]SLPAEEDSVLEK[136.11].L "sp|P27816|MAP4_HUMAN,tr|E7EVA0|E7EVA0_HUMAN,tr|A0A804HKE7|A0A804HKE7_HUMAN" 3 1483.6956 0.49 30270 14632 2 1483.698535 742.8551 Microtubule-associated protein 4 OS=Homo sapiens OX=9606 GN=MAP4 PE=1 SV=3 4 2740 - 720148 - - - 1.995 - 2.097 0.575 - 293.4 1 2 0 0.003 13 0 0 0 2.12E+06 4.32E+06 - - - 5.1876 1 221125_WJC_METTL3_EV_vs_WT_F03.14633.14633.3 1.47E-07 13/32 R.VVHIMDFQR.G "sp|P43243|MATR3_HUMAN,tr|D6RE02|D6RE02_HUMAN,tr|B3KM87|B3KM87_HUMAN,tr|A8MXP9|A8MXP9_HUMAN,tr|D6RAY2|D6RAY2_HUMAN,tr|D6R991|D6R991_HUMAN,tr|A0A0R4J2E8|A0A0R4J2E8_HUMAN,tr|D6RAM9|D6RAM9_HUMAN,tr|D6RIA2|D6RIA2_HUMAN,tr|H0Y8T4|H0Y8T4_HUMAN,tr|D6REM6|D6REM6_HUMAN,tr|D6RBI2|D6RBI2_HUMAN" 12 1143.5859 1.04 30271 14633 3 1143.583618 382.2026 Matrin-3 OS=Homo sapiens OX=9606 GN=MATR3 PE=1 SV=2 6.71 2740.2 - 590592 - - - -1.9946 - 2.346 0.543 - 307.9 1 2 0 -0.0023 9 0 0 0 9.64E+06 9.27E+06 - - - 7.1632 0.9998 221125_WJC_METTL3_EV_vs_WT_F03.14635.14635.2 0.0565 18-Oct K.VEEVELPVEK.V "sp|Q99873|ANM1_HUMAN,sp|Q9NR22|ANM8_HUMAN,tr|E9PQ98|E9PQ98_HUMAN,tr|E9PKG1|E9PKG1_HUMAN,tr|E9PNR9|E9PNR9_HUMAN,tr|H0YDE4|H0YDE4_HUMAN,tr|E9PIX6|E9PIX6_HUMAN" 7 1169.618 2.62 30272 14635 2 1169.618028 585.8163 Protein arginine N-methyltransferase 1 OS=Homo sapiens OX=9606 GN=PRMT1 PE=1 SV=3 4.09 2740.4 - 5.36E+06 - - - 0.0496 - 2.134 0.38 - 401.6 1 2 0 0.0001 10 0 0 0 1.03E+08 3.95E+07 - - - 3.9635 1 221125_WJC_METTL3_EV_vs_WT_F03.14637.14637.3 0.625 19/56 R.IPMSLGEPHAELDAK[136.11].G "sp|Q9NWS0|PIHD1_HUMAN,tr|M0QYF4|M0QYF4_HUMAN,tr|M0R3A4|M0R3A4_HUMAN,tr|M0R3A8|M0R3A8_HUMAN,tr|M0R028|M0R028_HUMAN,tr|M0QZM3|M0QZM3_HUMAN,tr|M0R1R3|M0R1R3_HUMAN,tr|M0QYA2|M0QYA2_HUMAN" 8 1614.8167 1.21 30273 14637 3 1614.815015 539.2795 PIH1 domain-containing protein 1 OS=Homo sapiens OX=9606 GN=PIH1D1 PE=1 SV=1 4.65 2740.6 - 5.29E+06 - - - -1.0391 - 3.436 0.506 - 452.6 1 2 0 -0.0017 15 0 0 0 1.98E+08 1.63E+08 - - - 7.4017 1 221125_WJC_METTL3_EV_vs_WT_F03.14638.14638.2 1.38E-07 13/20 K.TPYIVLSGSGK.S sp|O43290|SNUT1_HUMAN 1 1120.6128 2.39 30274 14638 2 1120.612516 561.3137 U4\U6.U5 tri-snRNP-associated protein 1 OS=Homo sapiens OX=9606 GN=SART1 PE=1 SV=1 8.26 2740.7 - 3.78E+06 - - - -0.2757 - 2.423 0.628 - 812.8 1 2 0 -0.0003 11 0 0 0 9.19E+07 3.84E+07 - - - 6.0735 0.9997 221125_WJC_METTL3_EV_vs_WT_F03.14641.14641.2 0.0102 18-Nov K.VEEVELPVEK[136.11].V "sp|Q99873|ANM1_HUMAN,sp|Q9NR22|ANM8_HUMAN,tr|E9PQ98|E9PQ98_HUMAN,tr|E9PKG1|E9PKG1_HUMAN,tr|E9PNR9|E9PNR9_HUMAN,tr|H0YDE4|H0YDE4_HUMAN,tr|E9PIX6|E9PIX6_HUMAN" 7 1177.6322 2.58 30277 14641 2 1177.63183 589.8234 Protein arginine N-methyltransferase 1 OS=Homo sapiens OX=9606 GN=PRMT1 PE=1 SV=3 4.09 2740.8 - 2.73E+06 - - - -0.2887 - 2.184 0.338 - 517.7 1 2 0 -0.0003 10 0 0 0 1.09E+08 4.21E+07 - - - 3.7178 0.9815 221125_WJC_METTL3_EV_vs_WT_F03.14642.14642.2 0.00232 14-Aug F.PSIVGR[166.11]PR[166.11].Q "sp|Q6S8J3|POTEE_HUMAN,sp|P63261|ACTG_HUMAN,sp|P68133|ACTS_HUMAN,sp|P62736|ACTA_HUMAN,sp|Q9BYX7|ACTBM_HUMAN,sp|P68032|ACTC_HUMAN,sp|P60709|ACTB_HUMAN,sp|P63267|ACTH_HUMAN,sp|A5A3E0|POTEF_HUMAN,sp|P0CG38|POTEI_HUMAN,tr|A0A804GS07|A0A804GS07_HUMAN,tr|I3L3I0|I3L3I0_HUMAN,tr|G5E9R0|G5E9R0_HUMAN,tr|E7EVS6|E7EVS6_HUMAN,tr|B8ZZJ2|B8ZZJ2_HUMAN,tr|J3KT65|J3KT65_HUMAN,tr|I3L3R2|I3L3R2_HUMAN,tr|K7EM38|K7EM38_HUMAN,tr|F6QUT6|F6QUT6_HUMAN,tr|C9JTX5|C9JTX5_HUMAN,tr|A0A6Q8PH58|A0A6Q8PH58_HUMAN,tr|F6UVQ4|F6UVQ4_HUMAN,tr|F8WB63|F8WB63_HUMAN,tr|I3L1U9|I3L1U9_HUMAN,tr|A0A2R8Y793|A0A2R8Y793_HUMAN,tr|I3L4N8|I3L4N8_HUMAN,tr|C9JUM1|C9JUM1_HUMAN,tr|F8WCH0|F8WCH0_HUMAN,tr|C9JZR7|C9JZR7_HUMAN,tr|C9JFL5|C9JFL5_HUMAN,tr|A0A2R8YGF8|A0A2R8YGF8_HUMAN,tr|A6NL76|A6NL76_HUMAN" 32 900.5408 1.1 30278 14642 2 900.540618 451.2777 POTE ankyrin domain family member E OS=Homo sapiens OX=9606 GN=POTEE PE=2 SV=3 12 2740.9 - 1.34E+06 - - - -0.2299 - 1.849 0.355 - 175.3 1 1 0 -0.0002 8 0 0 0 1.99E+08 1.81E+08 - - - 3.5167 0.9595 221125_WJC_METTL3_EV_vs_WT_F03.14643.14643.2 0.0127 12-Jul R.DYLHYIR[166.11].K "sp|P62280|RS11_HUMAN,tr|M0R1H5|M0R1H5_HUMAN,tr|M0QZC5|M0QZC5_HUMAN" 3 988.5006 2.45 30279 14643 2 988.504954 495.2576 40S ribosomal protein S11 OS=Homo sapiens OX=9606 GN=RPS11 PE=1 SV=3 6.74 2741 - 1.34E+06 - - - 4.4188 - 1.397 0.179 - 274.9 1 2 0 0.0044 7 0 0 0 5.51E+08 2.25E+08 - - - 1.4211 0.9036 221125_WJC_METTL3_EV_vs_WT_F03.14644.14644.2 0.124 14-Aug F.PSIVGRPR.Q "sp|Q6S8J3|POTEE_HUMAN,sp|P63261|ACTG_HUMAN,sp|P68133|ACTS_HUMAN,sp|P62736|ACTA_HUMAN,sp|Q9BYX7|ACTBM_HUMAN,sp|P68032|ACTC_HUMAN,sp|P60709|ACTB_HUMAN,sp|P63267|ACTH_HUMAN,sp|A5A3E0|POTEF_HUMAN,sp|P0CG38|POTEI_HUMAN,tr|A0A804GS07|A0A804GS07_HUMAN,tr|I3L3I0|I3L3I0_HUMAN,tr|G5E9R0|G5E9R0_HUMAN,tr|E7EVS6|E7EVS6_HUMAN,tr|B8ZZJ2|B8ZZJ2_HUMAN,tr|J3KT65|J3KT65_HUMAN,tr|I3L3R2|I3L3R2_HUMAN,tr|K7EM38|K7EM38_HUMAN,tr|F6QUT6|F6QUT6_HUMAN,tr|C9JTX5|C9JTX5_HUMAN,tr|A0A6Q8PH58|A0A6Q8PH58_HUMAN,tr|F6UVQ4|F6UVQ4_HUMAN,tr|F8WB63|F8WB63_HUMAN,tr|I3L1U9|I3L1U9_HUMAN,tr|A0A2R8Y793|A0A2R8Y793_HUMAN,tr|I3L4N8|I3L4N8_HUMAN,tr|C9JUM1|C9JUM1_HUMAN,tr|F8WCH0|F8WCH0_HUMAN,tr|C9JZR7|C9JZR7_HUMAN,tr|C9JFL5|C9JFL5_HUMAN,tr|A0A2R8YGF8|A0A2R8YGF8_HUMAN,tr|A6NL76|A6NL76_HUMAN" 32 880.5243 1.1 30280 14644 2 880.525384 441.2694 POTE ankyrin domain family member E OS=Homo sapiens OX=9606 GN=POTEE PE=2 SV=3 12 2741.1 - 1.08E+06 - - - 1.2481 - 1.862 0.177 - 165.4 1 1 0 0.0011 8 0 0 0 1.99E+08 1.81E+08 - - - 2.2228 0.9999 221125_WJC_METTL3_EV_vs_WT_F03.14649.14649.3 0.0026 Oct-40 R.AVFPSIVGR[166.11]PR[166.11].Q "sp|Q6S8J3|POTEE_HUMAN,sp|P63261|ACTG_HUMAN,sp|P68133|ACTS_HUMAN,sp|P62736|ACTA_HUMAN,sp|Q9BYX7|ACTBM_HUMAN,sp|P68032|ACTC_HUMAN,sp|P60709|ACTB_HUMAN,sp|P63267|ACTH_HUMAN,sp|A5A3E0|POTEF_HUMAN,sp|P0CG38|POTEI_HUMAN,tr|A0A804GS07|A0A804GS07_HUMAN,tr|I3L3I0|I3L3I0_HUMAN,tr|G5E9R0|G5E9R0_HUMAN,tr|E7EVS6|E7EVS6_HUMAN,tr|B8ZZJ2|B8ZZJ2_HUMAN,tr|J3KT65|J3KT65_HUMAN,tr|I3L3R2|I3L3R2_HUMAN,tr|K7EM38|K7EM38_HUMAN,tr|F6QUT6|F6QUT6_HUMAN,tr|C9JTX5|C9JTX5_HUMAN,tr|A0A6Q8PH58|A0A6Q8PH58_HUMAN,tr|F6UVQ4|F6UVQ4_HUMAN,tr|F8WB63|F8WB63_HUMAN,tr|I3L1U9|I3L1U9_HUMAN,tr|A0A2R8Y793|A0A2R8Y793_HUMAN,tr|I3L4N8|I3L4N8_HUMAN,tr|C9JUM1|C9JUM1_HUMAN,tr|F8WCH0|F8WCH0_HUMAN,tr|C9JZR7|C9JZR7_HUMAN,tr|C9JFL5|C9JFL5_HUMAN,tr|A0A2R8YGF8|A0A2R8YGF8_HUMAN,tr|A6NL76|A6NL76_HUMAN" 32 1217.7148 0.95 30283 14649 3 1217.713664 406.9122 POTE ankyrin domain family member E OS=Homo sapiens OX=9606 GN=POTEE PE=2 SV=3 12 2741.8 - 2.25E+07 - - - -0.905 - 2.138 0.381 - 152.8 1 2 0 -0.0011 11 0 0 0 1.78E+09 1.88E+09 - - - 4.9461 0.8442 221125_WJC_METTL3_EV_vs_WT_F03.14650.14650.2 0.000372 16-Nov V.FPSIVGRPR.Q "sp|Q6S8J3|POTEE_HUMAN,sp|P63261|ACTG_HUMAN,sp|P68133|ACTS_HUMAN,sp|P62736|ACTA_HUMAN,sp|Q9BYX7|ACTBM_HUMAN,sp|P68032|ACTC_HUMAN,sp|P60709|ACTB_HUMAN,sp|P63267|ACTH_HUMAN,sp|A5A3E0|POTEF_HUMAN,sp|P0CG38|POTEI_HUMAN,tr|A0A804GS07|A0A804GS07_HUMAN,tr|I3L3I0|I3L3I0_HUMAN,tr|G5E9R0|G5E9R0_HUMAN,tr|E7EVS6|E7EVS6_HUMAN,tr|B8ZZJ2|B8ZZJ2_HUMAN,tr|J3KT65|J3KT65_HUMAN,tr|I3L3R2|I3L3R2_HUMAN,tr|K7EM38|K7EM38_HUMAN,tr|F6QUT6|F6QUT6_HUMAN,tr|C9JTX5|C9JTX5_HUMAN,tr|A0A6Q8PH58|A0A6Q8PH58_HUMAN,tr|F6UVQ4|F6UVQ4_HUMAN,tr|F8WB63|F8WB63_HUMAN,tr|I3L1U9|I3L1U9_HUMAN,tr|A0A2R8Y793|A0A2R8Y793_HUMAN,tr|I3L4N8|I3L4N8_HUMAN,tr|C9JUM1|C9JUM1_HUMAN,tr|F8WCH0|F8WCH0_HUMAN,tr|C9JZR7|C9JZR7_HUMAN,tr|C9JFL5|C9JFL5_HUMAN,tr|A0A2R8YGF8|A0A2R8YGF8_HUMAN,tr|A6NL76|A6NL76_HUMAN" 32 1027.5927 0.95 30284 14650 2 1027.597369 514.8036 POTE ankyrin domain family member E OS=Homo sapiens OX=9606 GN=POTEE PE=2 SV=3 12 2741.9 - 2.36E+06 - - - 4.5446 - 2.002 0.398 - 301.6 1 1 0 0.0047 9 0 0 0 2.17E+08 2.27E+08 - - - 3.9874 0.9996 221125_WJC_METTL3_EV_vs_WT_F03.14651.14651.2 1.10E-07 20-Dec R.GPSGLLTYTGK[136.11].G "sp|Q9UHQ9|NB5R1_HUMAN,tr|H7C0R7|H7C0R7_HUMAN" 2 1100.5957 1 30285 14651 2 1100.599187 551.3051 NADH-cytochrome b5 reductase 1 OS=Homo sapiens OX=9606 GN=CYB5R1 PE=1 SV=1 8.59 2742 - 1.04E+06 - - - 3.1456 - 2.669 0.529 - 563.8 1 2 0 0.0035 11 0 0 0 2.05E+07 2.04E+07 - - - 5.6028 0.9897 221125_WJC_METTL3_EV_vs_WT_F03.14652.14652.2 0.0756 14-Sep R.QAVPLFSK.N "sp|Q9BZZ5|API5_HUMAN,tr|G3V1C3|G3V1C3_HUMAN" 2 888.5069 6.8 30286 14652 2 888.507001 445.2607 Apoptosis inhibitor 5 OS=Homo sapiens OX=9606 GN=API5 PE=1 SV=3 8.75 2742.1 - 1.02E+06 - - - 0.1103 - 1.457 0.058 - 256.1 1 2 0 0.0001 8 0 0 0 2.80E+07 4.12E+06 - - - 0.6045 0.9996 221125_WJC_METTL3_EV_vs_WT_F03.14653.14653.2 0.000966 14-Sep K.VPDFSEYR[166.11].R "sp|P0C7P4|UCRIL_HUMAN,sp|P47985|UCRI_HUMAN" 2 1021.4744 1.87 30287 14653 2 1021.475058 511.7445 Putative cytochrome b-c1 complex subunit Rieske-like protein 1 OS=Homo sapiens OX=9606 GN=UQCRFS1P1 PE=5 SV=1 4.37 2742.3 - 904799 - - - 0.6138 - 1.663 0.379 - 277.2 1 2 0 0.0006 8 0 0 0 3.68E+07 1.97E+07 - - - 3.3741 0.9989 221125_WJC_METTL3_EV_vs_WT_F03.14657.14657.2 0.0457 14-Aug R.LTLSQFQK[136.11].Q "sp|Q8N1F7|NUP93_HUMAN,tr|H3BVG0|H3BVG0_HUMAN" 2 971.5531 1.85 30289 14657 2 971.55236 486.7838 Nuclear pore complex protein Nup93 OS=Homo sapiens OX=9606 GN=NUP93 PE=1 SV=2 8.75 2742.8 - 4.10E+06 - - - -0.7946 - 1.4 0.317 - 169.8 1 2 0 -0.0008 8 0 0 0 1.12E+08 6.06E+07 - - - 2.3969 0.9998 221125_WJC_METTL3_EV_vs_WT_F03.14661.14661.3 0.000686 13/32 R.VVHIMDFQR[166.11].G "sp|P43243|MATR3_HUMAN,tr|D6RE02|D6RE02_HUMAN,tr|B3KM87|B3KM87_HUMAN,tr|A8MXP9|A8MXP9_HUMAN,tr|D6RAY2|D6RAY2_HUMAN,tr|D6R991|D6R991_HUMAN,tr|A0A0R4J2E8|A0A0R4J2E8_HUMAN,tr|D6RAM9|D6RAM9_HUMAN,tr|D6RIA2|D6RIA2_HUMAN,tr|H0Y8T4|H0Y8T4_HUMAN,tr|D6REM6|D6REM6_HUMAN,tr|D6RBI2|D6RBI2_HUMAN" 12 1153.5942 1.19 30293 14661 3 1153.595107 385.5387 Matrin-3 OS=Homo sapiens OX=9606 GN=MATR3 PE=1 SV=2 6.71 2743.2 - 586236 - - - 0.8131 - 1.938 0.375 - 226.3 1 2 0 0.0009 9 0 0 0 7.50E+09 6.32E+09 - - - 4.7147 1 221125_WJC_METTL3_EV_vs_WT_F03.14665.14665.2 1.80E-08 26-Dec L.YTIDTENSTVALAK[136.11].V "sp|Q8ND56|LS14A_HUMAN,tr|I3L4Q1|I3L4Q1_HUMAN,tr|A0A140TA76|A0A140TA76_HUMAN,tr|K7EMZ9|K7EMZ9_HUMAN" 4 1532.7814 0.96 30295 14665 2 1532.77866 767.398 Protein LSM14 homolog A OS=Homo sapiens OX=9606 GN=LSM14A PE=1 SV=3 4.37 2743.7 - 1.25E+06 - - - -1.7576 - 2.622 0.696 - 430.8 1 1 0 -0.0027 14 0 0 0 2.94E+07 3.05E+07 - - - 6.5998 0.9999 221125_WJC_METTL3_EV_vs_WT_F03.14666.14666.3 5.39E-05 Nov-36 R.RVLDELTLTK.A "sp|P13645|K1C10_HUMAN,tr|A0A1B0GVI3|A0A1B0GVI3_HUMAN" 2 1186.6921 12.22 30296 14666 3 1186.69182 396.5713 "Keratin, type I cytoskeletal 10 OS=Homo sapiens OX=9606 GN=KRT10 PE=1 SV=6" 6.07 2743.9 - 499624 - - - -0.268 - 2.02 0.475 - 154.6 1 2 0 -0.0003 10 0 0 0 1.45E+08 1.19E+07 - - - 5.889 0.9998 221125_WJC_METTL3_EV_vs_WT_F03.14667.14667.2 0.000169 20-Nov R.TNAENEFVTIK.K sp|P04264|K2C1_HUMAN 1 1264.6299 61.3 30297 14667 2 1264.628626 633.3222 "Keratin, type II cytoskeletal 1 OS=Homo sapiens OX=9606 GN=KRT1 PE=1 SV=6" 4.53 2743.9 - 5.65E+06 - - - -1.0327 - 2.098 0.461 - 475.4 1 2 0 -0.0013 11 0 0 0 1.60E+08 2.61E+06 - - - 4.4501 0.9901 221125_WJC_METTL3_EV_vs_WT_F03.14668.14668.2 0.949 20-Jul R.AVFPSIVGRPR.Q "sp|Q6S8J3|POTEE_HUMAN,sp|P63261|ACTG_HUMAN,sp|P68133|ACTS_HUMAN,sp|P62736|ACTA_HUMAN,sp|Q9BYX7|ACTBM_HUMAN,sp|P68032|ACTC_HUMAN,sp|P60709|ACTB_HUMAN,sp|P63267|ACTH_HUMAN,sp|A5A3E0|POTEF_HUMAN,sp|P0CG38|POTEI_HUMAN,tr|A0A804GS07|A0A804GS07_HUMAN,tr|I3L3I0|I3L3I0_HUMAN,tr|G5E9R0|G5E9R0_HUMAN,tr|E7EVS6|E7EVS6_HUMAN,tr|B8ZZJ2|B8ZZJ2_HUMAN,tr|J3KT65|J3KT65_HUMAN,tr|I3L3R2|I3L3R2_HUMAN,tr|K7EM38|K7EM38_HUMAN,tr|F6QUT6|F6QUT6_HUMAN,tr|C9JTX5|C9JTX5_HUMAN,tr|A0A6Q8PH58|A0A6Q8PH58_HUMAN,tr|F6UVQ4|F6UVQ4_HUMAN,tr|F8WB63|F8WB63_HUMAN,tr|I3L1U9|I3L1U9_HUMAN,tr|A0A2R8Y793|A0A2R8Y793_HUMAN,tr|I3L4N8|I3L4N8_HUMAN,tr|C9JUM1|C9JUM1_HUMAN,tr|F8WCH0|F8WCH0_HUMAN,tr|C9JZR7|C9JZR7_HUMAN,tr|C9JFL5|C9JFL5_HUMAN,tr|A0A2R8YGF8|A0A2R8YGF8_HUMAN,tr|A6NL76|A6NL76_HUMAN" 32 1197.6982 0.97 30298 14668 2 1197.698838 599.8564 POTE ankyrin domain family member E OS=Homo sapiens OX=9606 GN=POTEE PE=2 SV=3 12 2744 - 3.38E+06 - - - 0.511 - 1.202 0.155 - 93.3 1 2 0 0.0006 11 0 0 0 1.43E+08 1.47E+08 - - - 0.6834 0.9999 221125_WJC_METTL3_EV_vs_WT_F03.14670.14670.2 4.33E-07 20-Oct R.DNSTMGYMMAK[136.11].K "sp|P08238|HS90B_HUMAN,sp|Q58FF7|H90B3_HUMAN" 2 1255.5127 0.72 30300 14670 2 1255.512714 628.7636 Heat shock protein HSP 90-beta OS=Homo sapiens OX=9606 GN=HSP90AB1 PE=1 SV=4 5.83 2744.1 - 3.33E+06 - - - 0.039 - 1.838 0.618 - 342.7 1 2 0 0 11 0 0 0 4.75E+07 6.59E+07 - - - 5.2522 0.9869 221125_WJC_METTL3_EV_vs_WT_F03.14672.14672.2 0.0152 20-Dec K.VLQIVDNTVSR.Q "sp|O60315|ZEB2_HUMAN,tr|U3KQ51|U3KQ51_HUMAN,tr|E7EUW9|E7EUW9_HUMAN,tr|A0JP08|A0JP08_HUMAN,tr|A0A1B0GW50|A0A1B0GW50_HUMAN,tr|A0A1B0GV02|A0A1B0GV02_HUMAN,tr|A0A1X7SC99|A0A1X7SC99_HUMAN,tr|A0A1B0GVV8|A0A1B0GVV8_HUMAN" 8 1242.6932 0.26 30302 14672 2 1242.70075 622.3539 Zinc finger E-box-binding homeobox 2 OS=Homo sapiens OX=9606 GN=ZEB2 PE=1 SV=1 5.81 2744.3 - 1.19E+06 - - - 6.0747 - 2.199 0.313 - 678.9 1 2 0 0.0075 11 0 0 0 1.76E+07 6.90E+07 - - - 3.4822 1 221125_WJC_METTL3_EV_vs_WT_F03.14674.14674.2 5.25E-10 15/26 L.YTIDTENSTVALAK.V "sp|Q8ND56|LS14A_HUMAN,tr|I3L4Q1|I3L4Q1_HUMAN,tr|A0A140TA76|A0A140TA76_HUMAN,tr|K7EMZ9|K7EMZ9_HUMAN" 4 1524.7672 0.96 30304 14674 2 1524.765044 763.3909 Protein LSM14 homolog A OS=Homo sapiens OX=9606 GN=LSM14A PE=1 SV=3 4.37 2744.5 - 1.05E+06 - - - -1.3838 - 3.149 0.71 - 789.6 1 1 0 -0.0021 14 0 0 0 2.94E+07 3.05E+07 - - - 7.1629 1 221125_WJC_METTL3_EV_vs_WT_F03.14675.14675.2 5.11E-06 13/20 R.MEETPTEYLQR[166.11].G "sp|Q8NE71|ABCF1_HUMAN,tr|Q5STZ8|Q5STZ8_HUMAN,tr|H0YGW7|H0YGW7_HUMAN" 3 1405.6423 0.73 30305 14675 2 1405.64385 703.8284 ATP-binding cassette sub-family F member 1 OS=Homo sapiens OX=9606 GN=ABCF1 PE=1 SV=2 4.25 2744.6 - 1.02E+06 - - - 1.102 - 2.573 0.587 - 682.7 1 2 0 0.0015 11 0 0 0 2.54E+07 3.48E+07 - - - 5.9327 0.9997 221125_WJC_METTL3_EV_vs_WT_F03.14676.14676.2 0.000392 14/26 R.YVEVVPC[160.03]STEEMSR.V sp|Q9H6T0|ESRP2_HUMAN 1 1684.7437 1.1 30306 14676 2 1684.739071 843.3791 Epithelial splicing regulatory protein 2 OS=Homo sapiens OX=9606 GN=ESRP2 PE=1 SV=1 4.25 2744.7 - 545592 - - - -2.7227 - 2.468 0.591 - 489.5 1 2 0 -0.0046 14 0 0 0 5.96E+06 5.40E+06 - - - 5.6717 0.9903 221125_WJC_METTL3_EV_vs_WT_F03.14679.14679.2 3.71E-05 18-Sep R.SIFQHIQSAQ.S "sp|Q9Y2W1|TR150_HUMAN,tr|A0A3B3ITZ9|A0A3B3ITZ9_HUMAN" 2 1157.5829 - 30308 14679 2 1157.582325 579.7987 Thyroid hormone receptor-associated protein 3 OS=Homo sapiens OX=9606 GN=THRAP3 PE=1 SV=2 6.46 2745.1 - 6.46E+06 - - - -0.5157 - 1.854 0.495 - 219.4 1 1 0 -0.0006 10 0 0 0 - - - - - 4.4201 0.9999 221125_WJC_METTL3_EV_vs_WT_F03.14680.14680.2 3.02E-07 13/18 K.TDYTLSIANR.L sp|Q96P63|SPB12_HUMAN 1 1152.5775 42.57 30309 14680 2 1152.577058 577.296 Serpin B12 OS=Homo sapiens OX=9606 GN=SERPINB12 PE=1 SV=1 5.5 2745.1 - 1.75E+06 - - - -0.3852 - 2.307 0.545 - 669.2 1 2 0 -0.0004 10 0 0 0 8.77E+07 2.06E+06 - - - 5.3996 0.9999 221125_WJC_METTL3_EV_vs_WT_F03.14682.14682.3 0.00235 14/56 R.IPMSLGEPHAELDAK.G "sp|Q9NWS0|PIHD1_HUMAN,tr|M0QYF4|M0QYF4_HUMAN,tr|M0R3A4|M0R3A4_HUMAN,tr|M0R3A8|M0R3A8_HUMAN,tr|M0R028|M0R028_HUMAN,tr|M0QZM3|M0QZM3_HUMAN,tr|M0R1R3|M0R1R3_HUMAN,tr|M0QYA2|M0QYA2_HUMAN" 8 1606.8025 1.16 30311 14682 3 1606.801939 536.6081 PIH1 domain-containing protein 1 OS=Homo sapiens OX=9606 GN=PIH1D1 PE=1 SV=1 4.65 2745.2 - 1.02E+07 - - - -0.3448 - 2.301 0.388 - 196.9 1 2 0 -0.0006 15 0 0 0 1.99E+08 1.72E+08 - - - 5.0402 0.9996 221125_WJC_METTL3_EV_vs_WT_F03.14684.14684.2 0.000443 16-Dec R.SLNNFISQR[166.11].V "sp|Q9Y6D9|MD1L1_HUMAN,tr|C9JJ38|C9JJ38_HUMAN,tr|C9JIR0|C9JIR0_HUMAN" 3 1087.565 2.08 30313 14684 2 1087.566023 544.7898 Mitotic spindle assembly checkpoint protein MAD1 OS=Homo sapiens OX=9606 GN=MAD1L1 PE=1 SV=2 9.47 2745.4 - 1.81E+06 - - - 0.9618 - 1.919 0.374 - 567.7 1 2 0 0.001 9 0 0 0 9.77E+07 4.69E+07 - - - 3.6887 0.9978 221125_WJC_METTL3_EV_vs_WT_F03.14685.14685.2 2.86E-06 18-Sep R.MDVTSC[160.03]ISYR.N "sp|Q9Y6Y0|NS1BP_HUMAN,tr|H0Y5Y2|H0Y5Y2_HUMAN" 2 1230.5373 3.94 30314 14685 2 1230.531074 616.2759 Influenza virus NS1A-binding protein OS=Homo sapiens OX=9606 GN=IVNS1ABP PE=1 SV=3 5.59 2745.5 - 1.03E+06 - - - -5.0547 - 2.13 0.53 - 275.1 1 2 0 -0.0062 10 0 0 0 1.44E+07 3.66E+06 - - - 5.0642 0.9998 221125_WJC_METTL3_EV_vs_WT_F03.14686.14686.2 2.21E-06 20-Dec R.MEETPTEYLQR.G "sp|Q8NE71|ABCF1_HUMAN,tr|Q5STZ8|Q5STZ8_HUMAN,tr|H0YGW7|H0YGW7_HUMAN" 3 1395.634 0.73 30315 14686 2 1395.636256 698.8243 ATP-binding cassette sub-family F member 1 OS=Homo sapiens OX=9606 GN=ABCF1 PE=1 SV=2 4.25 2745.7 - 1.03E+06 - - - 1.5943 - 2.14 0.545 - 496.2 1 2 0 0.0022 11 0 0 0 2.54E+07 3.48E+07 - - - 5.1238 0.9997 221125_WJC_METTL3_EV_vs_WT_F03.14687.14687.3 0.000831 Oct-80 R.VTGEADVEFATHEDAVAAMSK[136.11].D "sp|P31943|HNRH1_HUMAN,tr|H0YBD7|H0YBD7_HUMAN,tr|H0YB39|H0YB39_HUMAN,tr|H0YBG7|H0YBG7_HUMAN,tr|E9PCY7|E9PCY7_HUMAN,tr|G8JLB6|G8JLB6_HUMAN" 6 2185.0089 1.25 30316 14687 3 2185.002962 729.3436 Heterogeneous nuclear ribonucleoprotein H OS=Homo sapiens OX=9606 GN=HNRNPH1 PE=1 SV=4 4.17 2745.8 - 526908 - - - -2.7011 - 1.978 0.449 - 18.7 1 2 0 -0.0059 21 0 0 0 7.00E+06 5.60E+06 - - - 5.1795 0.9998 221125_WJC_METTL3_EV_vs_WT_F03.14688.14688.2 0.00187 26-Oct R.YVEVVPC[160.03]STEEMSR[166.11].V sp|Q9H6T0|ESRP2_HUMAN 1 1694.7519 1.1 30317 14688 2 1694.748973 848.3832 Epithelial splicing regulatory protein 2 OS=Homo sapiens OX=9606 GN=ESRP2 PE=1 SV=1 4.25 2745.9 - 444380 - - - -1.7436 - 1.833 0.552 - 225.7 1 2 0 -0.003 14 0 0 0 5.96E+06 5.40E+06 - - - 4.6378 1 221125_WJC_METTL3_EV_vs_WT_F03.14694.14694.2 9.67E-08 20-Nov R.YYGINDPVADK[136.11].L sp|Q9NW64|RBM22_HUMAN 1 1261.607 0.56 30321 14694 2 1261.60496 631.8108 Pre-mRNA-splicing factor RBM22 OS=Homo sapiens OX=9606 GN=RBM22 PE=1 SV=1 4.21 2746.5 - 3.26E+06 - - - -1.6313 - 2.097 0.635 - 238.9 1 2 0 -0.0021 11 0 0 0 4.19E+07 7.52E+07 - - - 5.7337 0.9998 221125_WJC_METTL3_EV_vs_WT_F03.14695.14695.3 0.000594 Dec-48 K.VLHMSLNPTSVAR.Q sp|Q9Y6D9|MD1L1_HUMAN 1 1423.7606 3.27 30322 14695 3 1423.758367 475.5941 Mitotic spindle assembly checkpoint protein MAD1 OS=Homo sapiens OX=9606 GN=MAD1L1 PE=1 SV=2 9.73 2746.6 - 1.32E+06 - - - -1.5466 - 2.06 0.394 - 151 1 2 0 -0.0022 13 0 0 0 1.80E+07 5.50E+06 - - - 4.8916 0.9998 221125_WJC_METTL3_EV_vs_WT_F03.14696.14696.2 0.00301 14-Jul K.TSLSMFSK[136.11].S "sp|O60749|SNX2_HUMAN,tr|D6RC15|D6RC15_HUMAN" 2 907.4565 1.11 30323 14696 2 907.456346 454.7355 Sorting nexin-2 OS=Homo sapiens OX=9606 GN=SNX2 PE=1 SV=2 8.41 2746.7 - 1.11E+06 - - - -0.119 - 1.712 0.459 - 148.1 1 2 0 -0.0001 8 0 0 0 1.29E+07 1.16E+07 - - - 4.0527 1 221125_WJC_METTL3_EV_vs_WT_F03.14697.14697.2 1.87E-07 13/24 K.LYGNDFSQTTISR.F "sp|P14859|PO2F1_HUMAN,sp|P09086|PO2F2_HUMAN,sp|Q9UKI9|PO2F3_HUMAN,tr|U3KQ96|U3KQ96_HUMAN,tr|U3KQN1|U3KQN1_HUMAN,tr|H0YKT2|H0YKT2_HUMAN,tr|H0YNW1|H0YNW1_HUMAN,tr|B5ME60|B5ME60_HUMAN,tr|H0YLC5|H0YLC5_HUMAN,tr|A0A0C4DG88|A0A0C4DG88_HUMAN,tr|A0A0A0MT46|A0A0A0MT46_HUMAN,tr|H0YLL6|H0YLL6_HUMAN" 12 1500.7209 1.75 30324 14697 2 1500.720263 751.3677 "POU domain, class 2, transcription factor 1 OS=Homo sapiens OX=9606 GN=POU2F1 PE=1 SV=2" 5.84 2746.9 - 1.06E+06 - - - -0.4058 - 2.439 0.606 - 432.7 1 2 0 -0.0006 13 0 0 0 3.28E+08 1.87E+08 - - - 5.805 0.9998 221125_WJC_METTL3_EV_vs_WT_F03.14698.14698.2 3.91E-08 14/24 K.LYGNDFSQTTISR[166.11].F "sp|P14859|PO2F1_HUMAN,sp|P09086|PO2F2_HUMAN,sp|Q9UKI9|PO2F3_HUMAN,tr|U3KQ96|U3KQ96_HUMAN,tr|U3KQN1|U3KQN1_HUMAN,tr|H0YKT2|H0YKT2_HUMAN,tr|H0YNW1|H0YNW1_HUMAN,tr|B5ME60|B5ME60_HUMAN,tr|H0YLC5|H0YLC5_HUMAN,tr|A0A0C4DG88|A0A0C4DG88_HUMAN,tr|A0A0A0MT46|A0A0A0MT46_HUMAN,tr|H0YLL6|H0YLL6_HUMAN" 12 1510.7291 1.77 30325 14698 2 1510.732199 756.3718 "POU domain, class 2, transcription factor 1 OS=Homo sapiens OX=9606 GN=POU2F1 PE=1 SV=2" 5.84 2747 - 947742 - - - 2.0235 - 2.585 0.57 - 603.1 1 2 0 0.0031 13 0 0 0 3.32E+08 1.88E+08 - - - 5.6876 0.9992 221125_WJC_METTL3_EV_vs_WT_F03.14699.14699.3 0.698 13/36 R.TLTSIVHLER[166.11].T sp|Q7Z6Z7|HUWE1_HUMAN 1 1177.6694 0.33 30326 14699 3 1177.669439 393.5638 E3 ubiquitin-protein ligase HUWE1 OS=Homo sapiens OX=9606 GN=HUWE1 PE=1 SV=3 6.41 2747.1 - 903021 - - - -0.0025 - 2.263 0.225 - 241.8 1 2 0 0 10 0 0 0 5.04E+06 1.54E+07 - - - 3.4336 0.9986 221125_WJC_METTL3_EV_vs_WT_F03.14700.14700.2 0.0241 20-Oct K.EIEYVETVTSR[166.11].Q sp|Q9UHR4|BI2L1_HUMAN 1 1334.6593 1.79 30327 14700 2 1334.655301 668.3369 Brain-specific angiogenesis inhibitor 1-associated protein 2-like protein 1 OS=Homo sapiens OX=9606 GN=BAIAP2L1 PE=1 SV=2 4.25 2747.2 - 550874 - - - -3.0195 - 1.992 0.358 - 336.6 1 2 0 -0.004 11 0 0 0 6.80E+06 3.80E+06 - - - 3.5482 0.9988 221125_WJC_METTL3_EV_vs_WT_F03.14705.14705.2 0.000384 12-Jul K.FC[160.03]FPC[160.03]SR.Q "sp|Q7Z5L9|I2BP2_HUMAN,sp|Q8IU81|I2BP1_HUMAN,sp|Q9H1B7|I2BPL_HUMAN" 3 972.3946 1.32 30330 14705 2 972.395587 487.2046 Interferon regulatory factor 2-binding protein 2 OS=Homo sapiens OX=9606 GN=IRF2BP2 PE=1 SV=2 8.07 2747.9 - 2.91E+06 - - - 1.0222 - 1.412 0.313 - 195.5 1 2 0 0.001 7 0 0 0 9.77E+07 7.42E+07 - - - 2.4457 0.9996 221125_WJC_METTL3_EV_vs_WT_F03.14707.14707.2 0.0113 14/18 R.RVLDELTLTK.A "sp|P13645|K1C10_HUMAN,tr|A0A1B0GVI3|A0A1B0GVI3_HUMAN" 2 1186.6921 999 30332 14707 2 1186.692572 594.3533 "Keratin, type I cytoskeletal 10 OS=Homo sapiens OX=9606 GN=KRT10 PE=1 SV=6" 6.07 2748 - 1.57E+07 - - - 0.3657 - 2.515 0.23 - 897.6 1 2 0 0.0004 10 0 0 0 3.84E+08 0.00E+00 - - - 3.314 0.9999 221125_WJC_METTL3_EV_vs_WT_F03.14708.14708.2 7.90E-06 20-Sep K.LLETEC[160.03]PQYIR.K sp|P05109|S10A8_HUMAN 1 1420.7021 999 30333 14708 2 1420.702137 711.3583 Protein S100-A8 OS=Homo sapiens OX=9606 GN=S100A8 PE=1 SV=1 4.53 2748.1 - 1.83E+06 - - - 0.0605 - 2.155 0.528 - 307.7 1 2 0 0.0001 11 0 0 0 1.15E+08 0.00E+00 - - - 5.0178 0.9995 221125_WJC_METTL3_EV_vs_WT_F03.14709.14709.2 0.000534 18-Aug K.QYGNEVFLAK[136.11].L "sp|P50990|TCPQ_HUMAN,tr|H7C4C8|H7C4C8_HUMAN" 2 1175.6066 0.35 30334 14709 2 1175.607134 588.8106 T-complex protein 1 subunit theta OS=Homo sapiens OX=9606 GN=CCT8 PE=1 SV=4 6 2748.2 - 1.79E+06 - - - 0.4338 - 1.546 0.38 - 213.3 1 2 0 0.0005 10 0 0 0 1.09E+08 3.08E+08 - - - 3.0636 0.9999 221125_WJC_METTL3_EV_vs_WT_F03.14710.14710.3 3.41E-05 17/40 R.LK[136.11]VGLQVVAVK[136.11].A "sp|P10809|CH60_HUMAN,tr|A0A7I2V2X6|A0A7I2V2X6_HUMAN,tr|A0A7I2YQK6|A0A7I2YQK6_HUMAN,tr|A0A7I2V599|A0A7I2V599_HUMAN,tr|A0A7I2V5M1|A0A7I2V5M1_HUMAN" 5 1168.7878 1.15 30335 14710 3 1168.787519 390.6032 "60 kDa heat shock protein, mitochondrial OS=Homo sapiens OX=9606 GN=HSPD1 PE=1 SV=2" 10 2748.3 - 1.08E+06 - - - -0.2661 - 2.657 0.571 - 289.1 1 2 1 -0.0003 11 0 0 0 5.79E+08 5.02E+08 - - - 7.682 0.9988 221125_WJC_METTL3_EV_vs_WT_F03.14711.14711.3 0.00628 Nov-36 K.ATLEVILRPK.L "sp|Q9NQT4|EXOS5_HUMAN,tr|M0R102|M0R102_HUMAN" 2 1138.7074 0.93 30336 14711 3 1138.707419 380.5764 Exosome complex component RRP46 OS=Homo sapiens OX=9606 GN=EXOSC5 PE=1 SV=1 8.79 2748.4 - 1.06E+06 - - - 0.022 - 1.83 0.256 - 124.3 1 2 0 0 10 0 0 0 1.50E+07 1.61E+07 - - - 3.159 0.9998 221125_WJC_METTL3_EV_vs_WT_F03.14712.14712.2 1.18E-08 28-Dec R.VTPEPGAGPTQGLLR.A "sp|Q86YP4|P66A_HUMAN,tr|V9GY85|V9GY85_HUMAN,tr|V9GYX5|V9GYX5_HUMAN,tr|C9JJK9|C9JJK9_HUMAN,tr|H7C3H1|H7C3H1_HUMAN,tr|C9JVY3|C9JVY3_HUMAN,tr|C9JMI3|C9JMI3_HUMAN,tr|C9JGN4|C9JGN4_HUMAN" 8 1491.8045 1.77 30337 14712 2 1491.806844 746.9095 Transcriptional repressor p66-alpha OS=Homo sapiens OX=9606 GN=GATAD2A PE=1 SV=1 5.97 2748.5 - 543623 - - - 1.5431 - 2.289 0.595 - 187.8 1 2 0 0.0023 15 0 0 0 8.58E+07 4.85E+07 - - - 5.4709 0.9978 221125_WJC_METTL3_EV_vs_WT_F03.14715.14715.2 0.081 20-Jul R.AVFPSIVGR[166.11]PR[166.11].Q "sp|Q6S8J3|POTEE_HUMAN,sp|P63261|ACTG_HUMAN,sp|P68133|ACTS_HUMAN,sp|P62736|ACTA_HUMAN,sp|Q9BYX7|ACTBM_HUMAN,sp|P68032|ACTC_HUMAN,sp|P60709|ACTB_HUMAN,sp|P63267|ACTH_HUMAN,sp|A5A3E0|POTEF_HUMAN,sp|P0CG38|POTEI_HUMAN,tr|A0A804GS07|A0A804GS07_HUMAN,tr|I3L3I0|I3L3I0_HUMAN,tr|G5E9R0|G5E9R0_HUMAN,tr|E7EVS6|E7EVS6_HUMAN,tr|B8ZZJ2|B8ZZJ2_HUMAN,tr|J3KT65|J3KT65_HUMAN,tr|I3L3R2|I3L3R2_HUMAN,tr|K7EM38|K7EM38_HUMAN,tr|F6QUT6|F6QUT6_HUMAN,tr|C9JTX5|C9JTX5_HUMAN,tr|A0A6Q8PH58|A0A6Q8PH58_HUMAN,tr|F6UVQ4|F6UVQ4_HUMAN,tr|F8WB63|F8WB63_HUMAN,tr|I3L1U9|I3L1U9_HUMAN,tr|A0A2R8Y793|A0A2R8Y793_HUMAN,tr|I3L4N8|I3L4N8_HUMAN,tr|C9JUM1|C9JUM1_HUMAN,tr|F8WCH0|F8WCH0_HUMAN,tr|C9JZR7|C9JZR7_HUMAN,tr|C9JFL5|C9JFL5_HUMAN,tr|A0A2R8YGF8|A0A2R8YGF8_HUMAN,tr|A6NL76|A6NL76_HUMAN" 32 1217.7148 1.05 30338 14715 2 1217.714911 609.8647 POTE ankyrin domain family member E OS=Homo sapiens OX=9606 GN=POTEE PE=2 SV=3 12 2749 - 6.20E+06 - - - 0.1191 - 1.378 0.246 - 135.7 1 2 0 0.0001 11 0 0 0 2.02E+08 1.92E+08 - - - 1.7253 0.9995 221125_WJC_METTL3_EV_vs_WT_F03.14717.14717.2 4.43E-05 18-Nov R.QLANMVNNLK.E sp|P19474|RO52_HUMAN 1 1143.607 1.36 30340 14717 2 1143.608654 572.8108 E3 ubiquitin-protein ligase TRIM21 OS=Homo sapiens OX=9606 GN=TRIM21 PE=1 SV=1 8.75 2749 - 3.45E+06 - - - 1.4218 - 2.13 0.316 - 497 1 2 0 0.0016 10 0 0 0 5.81E+07 4.26E+07 - - - 3.485 0.9999 221125_WJC_METTL3_EV_vs_WT_F03.14719.14719.3 0.00102 14/40 R.LKVGLQVVAVK.A "sp|P10809|CH60_HUMAN,tr|A0A7I2V2X6|A0A7I2V2X6_HUMAN,tr|A0A7I2YQK6|A0A7I2YQK6_HUMAN,tr|A0A7I2V599|A0A7I2V599_HUMAN,tr|A0A7I2V5M1|A0A7I2V5M1_HUMAN" 5 1152.7594 1.15 30342 14719 3 1152.759567 385.2604 "60 kDa heat shock protein, mitochondrial OS=Homo sapiens OX=9606 GN=HSPD1 PE=1 SV=2" 10 2749.2 - 2.59E+06 - - - 0.1188 - 2.748 0.586 - 203.6 1 2 1 0.0001 11 0 0 0 5.86E+08 5.08E+08 - - - 7.945 0.9995 221125_WJC_METTL3_EV_vs_WT_F03.14720.14720.2 0.00529 18-Sep K.VYQWDDPDPR[166.11].L "sp|P49327|FAS_HUMAN,tr|A0A0U1RQF0|A0A0U1RQF0_HUMAN" 2 1299.5759 0.1 30343 14720 2 1299.576311 650.7952 Fatty acid synthase OS=Homo sapiens OX=9606 GN=FASN PE=1 SV=3 3.93 2749.2 - 1.87E+06 - - - 0.2886 - 1.487 0.398 - 194.6 1 2 0 0.0004 10 0 0 0 3.39E+06 3.24E+07 - - - 3.088 0.9997 221125_WJC_METTL3_EV_vs_WT_F03.14721.14721.3 0.00649 Oct-40 R.LDFTVEHDSLK.L "sp|Q15155|NOMO1_HUMAN,sp|Q5JPE7|NOMO2_HUMAN,sp|P69849|NOMO3_HUMAN,tr|A0A7I2V686|A0A7I2V686_HUMAN,tr|A0A7I2V3P4|A0A7I2V3P4_HUMAN,tr|A0A7I2V6B0|A0A7I2V6B0_HUMAN,tr|A0A7I2V4D7|A0A7I2V4D7_HUMAN,tr|A0A7I2V4T6|A0A7I2V4T6_HUMAN,tr|A0A0G2JP90|A0A0G2JP90_HUMAN,tr|A0A087X117|A0A087X117_HUMAN,tr|A0A0G2JN29|A0A0G2JN29_HUMAN,tr|A0A7I2V2Z5|A0A7I2V2Z5_HUMAN,tr|A0A087WW46|A0A087WW46_HUMAN,tr|J3KN36|J3KN36_HUMAN" 14 1302.6456 1.05 30344 14721 3 1302.644601 435.2225 Nodal modulator 1 OS=Homo sapiens OX=9606 GN=NOMO1 PE=1 SV=5 4.54 2749.4 - 1.11E+06 - - - -0.7531 - 1.849 0.347 - 111.5 1 2 0 -0.001 11 0 0 0 1.17E+07 1.12E+07 - - - 4.1545 0.9999 221125_WJC_METTL3_EV_vs_WT_F03.14724.14724.2 1.21E-08 13/24 K.VGDDVEFEVSSDR.R "sp|O75534|CSDE1_HUMAN,tr|E9PLD4|E9PLD4_HUMAN" 2 1452.6369 0.76 30347 14724 2 1452.637921 727.3257 Cold shock domain-containing protein E1 OS=Homo sapiens OX=9606 GN=CSDE1 PE=1 SV=2 3.77 2749.7 - 436529 - - - 0.7249 - 2.644 0.556 - 589 1 2 0 0.0011 13 0 0 0 5.60E+06 7.35E+06 - - - 5.6427 0.9997 221125_WJC_METTL3_EV_vs_WT_F03.14725.14725.2 5.05E-05 20-Aug R.AVEEQIEYLQK.K sp|Q5VTR2|BRE1A_HUMAN 1 1348.6874 0.4 30348 14725 2 1348.689142 675.351 E3 ubiquitin-protein ligase BRE1A OS=Homo sapiens OX=9606 GN=RNF20 PE=1 SV=2 4.25 2749.8 - 347271 - - - 1.2568 - 1.957 0.438 - 193.3 1 2 0 0.0017 11 0 0 0 7.07E+06 1.77E+07 - - - 4.0919 0.9722 221125_WJC_METTL3_EV_vs_WT_F03.14729.14729.2 0.00918 18-Aug K.QYGNEVFLAK.L "sp|P50990|TCPQ_HUMAN,tr|H7C4C8|H7C4C8_HUMAN" 2 1167.5924 0.36 30350 14729 2 1167.596682 584.8035 T-complex protein 1 subunit theta OS=Homo sapiens OX=9606 GN=CCT8 PE=1 SV=4 6 2750.3 - 1.80E+06 - - - 3.6468 - 1.382 0.182 - 176.1 1 2 0 0.0043 10 0 0 0 1.07E+08 3.02E+08 - - - 1.287 0.9998 221125_WJC_METTL3_EV_vs_WT_F03.14730.14730.2 0.000118 22-Sep K.YQLDPTASISAK[136.11].V "sp|P45880|VDAC2_HUMAN,tr|A0A0A0MR02|A0A0A0MR02_HUMAN" 2 1300.6754 1.31 30351 14730 2 1300.67714 651.345 Voltage-dependent anion-selective channel protein 2 OS=Homo sapiens OX=9606 GN=VDAC2 PE=1 SV=2 5.83 2750.3 - 2.19E+06 - - - 1.3132 - 1.847 0.549 - 154 1 2 0 0.0017 12 0 0 0 2.62E+08 2.01E+08 - - - 4.7098 0.9994 221125_WJC_METTL3_EV_vs_WT_F03.14731.14731.2 0.0172 20-Oct R.SGASLLSNMSR.H sp|Q13835|PKP1_HUMAN 1 1121.5499 10.67 30352 14731 2 1121.551539 561.7822 Plakophilin-1 OS=Homo sapiens OX=9606 GN=PKP1 PE=1 SV=2 9.47 2750.4 - 1.19E+06 - - - 1.4551 - 1.842 0.353 - 389.1 1 2 0 0.0016 11 0 0 0 1.88E+07 1.76E+06 - - - 3.3002 0.9999 221125_WJC_METTL3_EV_vs_WT_F03.14732.14732.3 9.52E-05 13/44 R.INGIFPGTPLKK.D sp|Q86XN7|PRSR1_HUMAN 1 1283.7602 1.47 30353 14732 3 1283.760826 428.9273 Proline and serine-rich protein 1 OS=Homo sapiens OX=9606 GN=PROSER1 PE=1 SV=2 10 2750.5 - 991083 - - - 0.5203 - 2.266 0.425 - 208.2 1 2 0 0.0007 12 0 0 0 2.09E+07 1.42E+07 - - - 5.5456 0.9998 221125_WJC_METTL3_EV_vs_WT_F03.14733.14733.2 1.24E-05 14/22 K.LSLQEQDAAIVK.N sp|Q9Y6D9|MD1L1_HUMAN 1 1313.7191 1.83 30354 14733 2 1313.721524 657.8668 Mitotic spindle assembly checkpoint protein MAD1 OS=Homo sapiens OX=9606 GN=MAD1L1 PE=1 SV=2 4.37 2750.6 - 795554 - - - 1.8596 - 2.871 0.491 - 844.7 1 2 0 0.0024 12 0 0 0 8.27E+07 4.52E+07 - - - 5.4417 1 221125_WJC_METTL3_EV_vs_WT_F03.14734.14734.2 3.70E-08 13/24 K.VGDDVEFEVSSDR[166.11].R "sp|O75534|CSDE1_HUMAN,tr|E9PLD4|E9PLD4_HUMAN" 2 1462.6451 0.76 30355 14734 2 1462.643063 732.3298 Cold shock domain-containing protein E1 OS=Homo sapiens OX=9606 GN=CSDE1 PE=1 SV=2 3.77 2750.8 - 718422 - - - -1.4187 - 2.606 0.579 - 613.9 1 2 0 -0.0021 13 0 0 0 5.60E+06 7.35E+06 - - - 5.7751 0.9999 221125_WJC_METTL3_EV_vs_WT_F03.14743.14743.2 0.00393 16-Aug K.IDYGEYMDK.N "sp|Q04837|SSBP_HUMAN,tr|A0A0G2JLD8|A0A0G2JLD8_HUMAN,tr|E7EUY5|E7EUY5_HUMAN" 3 1132.4747 1.35 30362 14743 2 1132.474792 567.2446 "Single-stranded DNA-binding protein, mitochondrial OS=Homo sapiens OX=9606 GN=SSBP1 PE=1 SV=1" 4.03 2752 - 5.23E+06 - - - 0.1015 - 1.84 0.536 - 171.6 1 2 0 0.0001 9 0 0 0 1.05E+08 7.77E+07 - - - 4.7639 0.9999 221125_WJC_METTL3_EV_vs_WT_F03.14744.14744.2 0.000262 16-Aug K.IDYGEYMDK[136.11].N "sp|Q04837|SSBP_HUMAN,tr|A0A0G2JLD8|A0A0G2JLD8_HUMAN,tr|E7EUY5|E7EUY5_HUMAN" 3 1140.4889 1.35 30363 14744 2 1140.488881 571.2517 "Single-stranded DNA-binding protein, mitochondrial OS=Homo sapiens OX=9606 GN=SSBP1 PE=1 SV=1" 4.03 2752 - 3.91E+06 - - - 0.0035 - 1.807 0.538 - 189.4 1 2 0 0 9 0 0 0 1.05E+08 7.77E+07 - - - 4.7264 0.9988 221125_WJC_METTL3_EV_vs_WT_F03.14745.14745.2 0.0259 18-Oct K.QSLPPGLAVK[136.11].E sp|P63173|RL38_HUMAN 1 1016.611 1.48 30364 14745 2 1016.610957 509.3128 60S ribosomal protein L38 OS=Homo sapiens OX=9606 GN=RPL38 PE=1 SV=2 8.75 2752.1 - 1.77E+06 - - - -0.0236 - 1.727 0.221 - 277.3 1 2 0 0 10 0 0 0 4.23E+08 2.86E+08 - - - 2.1984 0.9999 221125_WJC_METTL3_EV_vs_WT_F03.14746.14746.2 1.63E-05 14/22 K.LSQNIAVQTDFK.T sp|Q8ND24|RN214_HUMAN 1 1362.7143 2.91 30365 14746 2 1362.714416 682.3644 RING finger protein 214 OS=Homo sapiens OX=9606 GN=RNF214 PE=1 SV=2 5.84 2752.3 - 1.74E+06 - - - 0.0631 - 3.163 0.485 - 856.7 1 2 0 0.0001 12 0 0 0 2.22E+07 7.64E+06 - - - 5.653 0.9997 221125_WJC_METTL3_EV_vs_WT_F03.14747.14747.2 1.86E-05 13/22 K.LSLQEQDAAIVK[136.11].N sp|Q9Y6D9|MD1L1_HUMAN 1 1321.7333 1.85 30366 14747 2 1321.736429 661.8739 Mitotic spindle assembly checkpoint protein MAD1 OS=Homo sapiens OX=9606 GN=MAD1L1 PE=1 SV=2 4.37 2752.4 - 1.19E+06 - - - 2.3817 - 2.595 0.473 - 642.1 1 2 0 0.0031 12 0 0 0 8.27E+07 4.48E+07 - - - 5.0426 0.9942 221125_WJC_METTL3_EV_vs_WT_F03.14749.14749.2 1.45 18-Oct R.ALDDISESIK[136.11].E "sp|Q9Y3B8|ORN_HUMAN,tr|H0YGR4|H0YGR4_HUMAN,tr|F5GYG5|F5GYG5_HUMAN,tr|H0YG54|H0YG54_HUMAN" 4 1097.5696 1.49 30368 14749 2 1097.570001 549.7921 "Oligoribonuclease, mitochondrial OS=Homo sapiens OX=9606 GN=REXO2 PE=1 SV=3" 4.03 2752.7 - 664016 - - - 0.3927 - 1.661 0.079 - 269 1 2 0 0.0004 10 0 0 0 1.98E+07 1.33E+07 - - - 1.0407 0.9999 221125_WJC_METTL3_EV_vs_WT_F03.14751.14751.2 2.25E-05 14/28 K.ASEVMGPVEAAPEYR.V "sp|Q8WWY3|PRP31_HUMAN,tr|E7EVX8|E7EVX8_HUMAN,tr|E7EU94|E7EU94_HUMAN,tr|E7ESX0|E7ESX0_HUMAN,tr|E7EN72|E7EN72_HUMAN" 5 1604.7505 2.76 30370 14751 2 1604.748685 803.3825 U4\U6 small nuclear ribonucleoprotein Prp31 OS=Homo sapiens OX=9606 GN=PRPF31 PE=1 SV=2 4.25 2752.9 - 574236 - - - -1.1048 - 2.62 0.507 - 677.7 1 2 0 -0.0018 15 0 0 0 1.54E+08 5.58E+07 - - - 5.1532 0.9997 221125_WJC_METTL3_EV_vs_WT_F03.14752.14752.2 0.000446 20-Nov K.VEAQLQELQVK.F sp|P35579|MYH9_HUMAN 1 1283.7085 1.05 30371 14752 2 1283.706154 642.8615 Myosin-9 OS=Homo sapiens OX=9606 GN=MYH9 PE=1 SV=4 4.53 2753 - 484870 - - - -1.84 - 2.643 0.38 - 485.4 1 2 0 -0.0024 11 0 0 0 5.59E+07 5.35E+07 - - - 4.4762 0.9952 221125_WJC_METTL3_EV_vs_WT_F03.14753.14753.2 0.125 18-Jul R.SQTGVQILMK.L sp|Q9NWK9|BCD1_HUMAN 1 1103.6009 0.5 30372 14753 2 1103.60236 552.8077 Box C\D snoRNA protein 1 OS=Homo sapiens OX=9606 GN=ZNHIT6 PE=1 SV=1 8.47 2753.1 - 430834 - - - 1.3411 - 1.348 0.216 - 138.3 1 2 0 0.0015 10 0 0 0 3.32E+06 6.64E+06 - - - 1.4695 0.9967 221125_WJC_METTL3_EV_vs_WT_F03.14759.14759.2 0.00913 20-Sep R.LK[136.11]VGLQVVAVK[136.11].A "sp|P10809|CH60_HUMAN,tr|A0A7I2V2X6|A0A7I2V2X6_HUMAN,tr|A0A7I2YQK6|A0A7I2YQK6_HUMAN,tr|A0A7I2V599|A0A7I2V599_HUMAN,tr|A0A7I2V5M1|A0A7I2V5M1_HUMAN" 5 1168.7878 1.2 30376 14759 2 1168.787994 585.4012 "60 kDa heat shock protein, mitochondrial OS=Homo sapiens OX=9606 GN=HSPD1 PE=1 SV=2" 10 2753.9 - 1.12E+07 - - - 0.1403 - 1.794 0.403 - 140.5 1 2 1 0.0002 11 0 0 0 1.66E+08 1.38E+08 - - - 3.5986 0.9989 221125_WJC_METTL3_EV_vs_WT_F03.14760.14760.2 0.000123 16/20 R.LKVGLQVVAVK.A "sp|P10809|CH60_HUMAN,tr|A0A7I2V2X6|A0A7I2V2X6_HUMAN,tr|A0A7I2YQK6|A0A7I2YQK6_HUMAN,tr|A0A7I2V599|A0A7I2V599_HUMAN,tr|A0A7I2V5M1|A0A7I2V5M1_HUMAN" 5 1152.7594 1.2 30377 14760 2 1152.759416 577.387 "60 kDa heat shock protein, mitochondrial OS=Homo sapiens OX=9606 GN=HSPD1 PE=1 SV=2" 10 2754 - 1.08E+07 - - - -0.0121 - 2.65 0.493 - 526.2 1 2 1 0 11 0 0 0 1.66E+08 1.38E+08 - - - 5.3187 0.9962 221125_WJC_METTL3_EV_vs_WT_F03.14761.14761.2 0.0403 18-Sep K.QSLPPGLAVK.E sp|P63173|RL38_HUMAN 1 1008.5968 1.47 30378 14761 2 1008.596257 505.3057 60S ribosomal protein L38 OS=Homo sapiens OX=9606 GN=RPL38 PE=1 SV=2 8.75 2754 - 2.30E+06 - - - -0.5195 - 1.486 0.16 - 187.6 1 2 0 -0.0005 10 0 0 0 4.43E+08 3.02E+08 - - - 1.3282 0.9993 221125_WJC_METTL3_EV_vs_WT_F03.14764.14764.2 0.146 18-Oct R.LNLNNTVLSK[136.11].R "sp|P07814|SYEP_HUMAN,tr|V9GYZ6|V9GYZ6_HUMAN" 2 1122.6488 0.89 30381 14764 2 1122.647132 562.3317 Bifunctional glutamate\proline--tRNA ligase OS=Homo sapiens OX=9606 GN=EPRS1 PE=1 SV=5 8.75 2754.3 - 1.07E+06 - - - -1.5063 - 2.123 0.26 - 260.2 1 2 0 -0.0017 10 0 0 0 1.39E+08 1.56E+08 - - - 3.0622 1 221125_WJC_METTL3_EV_vs_WT_F03.14765.14765.2 7.68E-10 18/30 K.LIAPVAEEEATVPNNK.L "sp|P07195|LDHB_HUMAN,tr|A8MW50|A8MW50_HUMAN,tr|A0A3B3IS95|A0A3B3IS95_HUMAN,tr|C9J7H8|C9J7H8_HUMAN,tr|F5H793|F5H793_HUMAN,tr|A0A5F9ZHM4|A0A5F9ZHM4_HUMAN" 6 1693.8887 0.94 30382 14765 2 1693.89008 847.9516 L-lactate dehydrogenase B chain OS=Homo sapiens OX=9606 GN=LDHB PE=1 SV=2 4.25 2754.5 - 834726 - - - 0.8348 - 3.076 0.663 - 706.6 1 2 0 0.0014 16 0 0 0 5.15E+07 5.48E+07 - - - 6.7 0.987 221125_WJC_METTL3_EV_vs_WT_F03.14766.14766.2 0.0817 18-Nov R.LNLNNTVLSK.R "sp|P07814|SYEP_HUMAN,tr|V9GYZ6|V9GYZ6_HUMAN" 2 1114.6346 0.89 30383 14766 2 1114.639331 558.3246 Bifunctional glutamate\proline--tRNA ligase OS=Homo sapiens OX=9606 GN=EPRS1 PE=1 SV=5 8.75 2754.6 - 775398 - - - 4.2238 - 1.643 0.245 - 297.1 1 2 0 0.0047 10 0 0 0 1.39E+08 1.56E+08 - - - 2.235 0.9974 221125_WJC_METTL3_EV_vs_WT_F03.14767.14767.2 0.0106 14-Jul K.EFTNVYIK[136.11].N "sp|Q13310|PABP4_HUMAN,sp|P11940|PABP1_HUMAN,sp|P0CB38|PAB4L_HUMAN,tr|A0A7I2V5W9|A0A7I2V5W9_HUMAN,tr|A0A7I2YQE4|A0A7I2YQE4_HUMAN,tr|A0A7I2V649|A0A7I2V649_HUMAN,tr|B1ANR0|B1ANR0_HUMAN,tr|A0A7I2V4L7|A0A7I2V4L7_HUMAN,tr|H0YCC8|H0YCC8_HUMAN,tr|H0YAR2|H0YAR2_HUMAN,tr|E7ERJ7|E7ERJ7_HUMAN,tr|A0A7I2V598|A0A7I2V598_HUMAN,tr|A0A7I2YQ88|A0A7I2YQ88_HUMAN,tr|H0Y5F5|H0Y5F5_HUMAN,tr|H0YBN4|H0YBN4_HUMAN,tr|A0A087WTT1|A0A087WTT1_HUMAN,tr|A0A7I2YQ90|A0A7I2YQ90_HUMAN,tr|A0A7I2V4N4|A0A7I2V4N4_HUMAN,tr|E7EQV3|E7EQV3_HUMAN" 19 1020.5371 1.38 30384 14767 2 1020.534843 511.2758 Polyadenylate-binding protein 4 OS=Homo sapiens OX=9606 GN=PABPC4 PE=1 SV=1 6.1 2754.7 - 568055 - - - -2.2576 - 1.437 0.301 - 170.6 1 2 0 -0.0023 8 0 0 0 2.29E+07 1.65E+07 - - - 2.3569 0.9999 221125_WJC_METTL3_EV_vs_WT_F03.14768.14768.2 1.01E-06 13/28 K.ASEVMGPVEAAPEYR[166.11].V "sp|Q8WWY3|PRP31_HUMAN,tr|E7EVX8|E7EVX8_HUMAN,tr|E7EU94|E7EU94_HUMAN,tr|E7ESX0|E7ESX0_HUMAN,tr|E7EN72|E7EN72_HUMAN" 5 1614.7587 2.76 30385 14768 2 1614.756412 808.3866 U4\U6 small nuclear ribonucleoprotein Prp31 OS=Homo sapiens OX=9606 GN=PRPF31 PE=1 SV=2 4.25 2754.9 - 487205 - - - -1.4343 - 2.859 0.526 - 555.8 1 2 0 -0.0023 15 0 0 0 1.54E+08 5.58E+07 - - - 5.5079 0.9992 221125_WJC_METTL3_EV_vs_WT_F03.14770.14770.2 0.000103 16-Sep K.AVQDLC[160.03]GWR.L sp|Q9P258|RCC2_HUMAN 1 1103.5182 0.56 30387 14770 2 1103.515431 552.7664 Protein RCC2 OS=Homo sapiens OX=9606 GN=RCC2 PE=1 SV=2 5.87 2755.1 - 274501 - - - -2.521 - 1.773 0.419 - 307.4 1 2 0 -0.0028 9 0 0 0 1.69E+07 3.03E+07 - - - 3.7916 0.9997 221125_WJC_METTL3_EV_vs_WT_F03.14773.14773.2 1.01E-05 18-Oct K.NLQYYDISAK[136.11].S "sp|P62826|RAN_HUMAN,tr|B5MDF5|B5MDF5_HUMAN,tr|J3KQE5|J3KQE5_HUMAN,tr|B4DV51|B4DV51_HUMAN,tr|F5H018|F5H018_HUMAN" 5 1221.6121 0.87 30388 14773 2 1221.610344 611.8133 GTP-binding nuclear protein Ran OS=Homo sapiens OX=9606 GN=RAN PE=1 SV=3 5.83 2755.5 - 3.63E+06 - - - -1.4399 - 1.92 0.47 - 311.2 1 2 0 -0.0018 10 0 0 0 3.84E+08 4.40E+08 - - - 4.3327 0.9995 221125_WJC_METTL3_EV_vs_WT_F03.14774.14774.2 0.00458 14-Oct K.TTLLHMLK[136.11].D "sp|Q9NR31|SAR1A_HUMAN,sp|Q9Y6B6|SAR1B_HUMAN,tr|D6RAA2|D6RAA2_HUMAN,tr|D6RD69|D6RD69_HUMAN,tr|X1WI22|X1WI22_HUMAN,tr|Q5SQT8|Q5SQT8_HUMAN,tr|D6RDB2|D6RDB2_HUMAN" 7 963.5667 1.09 30389 14774 2 963.567948 482.7906 GTP-binding protein SAR1a OS=Homo sapiens OX=9606 GN=SAR1A PE=1 SV=1 8.44 2755.6 - 2.09E+06 - - - 1.3232 - 1.865 0.348 - 375.5 1 2 0 0.0013 8 0 0 0 1.26E+08 1.15E+08 - - - 3.4907 0.9993 221125_WJC_METTL3_EV_vs_WT_F03.14775.14775.2 0.0518 14-Aug K.QLIDITGK.N "sp|Q14157|UBP2L_HUMAN,tr|Q5VU78|Q5VU78_HUMAN,tr|F8W726|F8W726_HUMAN,tr|Q5VU81|Q5VU81_HUMAN,tr|Q5VU79|Q5VU79_HUMAN,tr|Q5VU80|Q5VU80_HUMAN,tr|Q5VU77|Q5VU77_HUMAN" 7 886.5124 2.1 30390 14775 2 886.511835 444.2635 Ubiquitin-associated protein 2-like OS=Homo sapiens OX=9606 GN=UBAP2L PE=1 SV=2 5.84 2755.8 - 1.59E+06 - - - -0.6182 - 1.651 0.302 - 230.2 1 2 0 -0.0005 8 0 0 0 9.94E+08 4.74E+08 - - - 2.7835 0.9869 221125_WJC_METTL3_EV_vs_WT_F03.14779.14779.2 0.000963 14-Sep K.QYFEQFGK[136.11].V "sp|O43347|MSI1H_HUMAN,sp|Q96DH6|MSI2H_HUMAN,tr|B4DHE8|B4DHE8_HUMAN,tr|H0YHB7|H0YHB7_HUMAN,tr|A0A6Q8PF05|A0A6Q8PF05_HUMAN,tr|B4DM51|B4DM51_HUMAN,tr|J3KTC1|J3KTC1_HUMAN" 7 1053.5011 1.31 30394 14779 2 1053.507992 527.7578 RNA-binding protein Musashi homolog 1 OS=Homo sapiens OX=9606 GN=MSI1 PE=1 SV=1 6 2756.1 - 978702 - - - 6.5458 - 1.472 0.491 - 229.9 1 2 0 0.0069 8 0 0 0 1.55E+09 1.19E+09 - - - 3.8314 1 221125_WJC_METTL3_EV_vs_WT_F03.14781.14781.3 1.78E-07 15/56 R.VTPEPGAGPTQGLLR.A "sp|Q86YP4|P66A_HUMAN,tr|V9GY85|V9GY85_HUMAN,tr|V9GYX5|V9GYX5_HUMAN,tr|C9JJK9|C9JJK9_HUMAN,tr|H7C3H1|H7C3H1_HUMAN,tr|C9JVY3|C9JVY3_HUMAN,tr|C9JMI3|C9JMI3_HUMAN,tr|C9JGN4|C9JGN4_HUMAN" 8 1491.8045 1.74 30396 14781 3 1491.803509 498.2755 Transcriptional repressor p66-alpha OS=Homo sapiens OX=9606 GN=GATAD2A PE=1 SV=1 5.97 2756.4 - 752429 - - - -0.6924 - 3.1 0.486 - 277.4 1 2 0 -0.001 15 0 0 0 1.35E+07 7.78E+06 - - - 6.9104 0.9838 221125_WJC_METTL3_EV_vs_WT_F03.14782.14782.2 0.0386 18-Dec L.KVGLQVVAVK.A "sp|P10809|CH60_HUMAN,tr|A0A7I2V2X6|A0A7I2V2X6_HUMAN,tr|A0A7I2YQK6|A0A7I2YQK6_HUMAN,tr|A0A7I2V599|A0A7I2V599_HUMAN,tr|A0A7I2V5M1|A0A7I2V5M1_HUMAN" 5 1039.6754 1.27 30397 14782 2 1039.675159 520.845 "60 kDa heat shock protein, mitochondrial OS=Homo sapiens OX=9606 GN=HSPD1 PE=1 SV=2" 10 2756.5 - 746242 - - - -0.1991 - 1.897 0.386 - 355.7 1 1 0 -0.0002 10 0 0 0 9.08E+06 7.14E+06 - - - 3.6791 0.9773 221125_WJC_METTL3_EV_vs_WT_F03.14784.14784.2 0.00231 24-Sep L.GYPGFQATTYASR[166.11].S "sp|O43347|MSI1H_HUMAN,tr|H0YHB7|H0YHB7_HUMAN" 2 1427.6709 1.59 30399 14784 2 1427.672081 714.8427 RNA-binding protein Musashi homolog 1 OS=Homo sapiens OX=9606 GN=MSI1 PE=1 SV=1 8.59 2756.8 - 512568 - - - 0.8279 - 1.764 0.409 - 182.6 1 1 0 0.0012 13 0 0 0 1.09E+07 6.85E+06 - - - 3.5182 0.9999 221125_WJC_METTL3_EV_vs_WT_F03.14787.14787.2 3.78E-05 22-Dec K.ILQDGGLQVVEK.Q "sp|O43175|SERA_HUMAN,tr|A0A2C9F2M7|A0A2C9F2M7_HUMAN,tr|A0A286YFB2|A0A286YFB2_HUMAN,tr|A0A286YF34|A0A286YF34_HUMAN,tr|A0A286YFC8|A0A286YFC8_HUMAN,tr|A0A286YF22|A0A286YF22_HUMAN,tr|A0A286YFL2|A0A286YFL2_HUMAN,tr|A0A286YFA2|A0A286YFA2_HUMAN,tr|A0A286YFM8|A0A286YFM8_HUMAN,tr|A0A286YER3|A0A286YER3_HUMAN,tr|A0A286YFF3|A0A286YFF3_HUMAN,tr|A0A286YFK5|A0A286YFK5_HUMAN" 12 1297.7242 1.28 30400 14787 2 1297.724208 649.8694 D-3-phosphoglycerate dehydrogenase OS=Homo sapiens OX=9606 GN=PHGDH PE=1 SV=4 4.37 2757.1 - 1.60E+07 - - - 0.0324 - 2.396 0.519 - 400.2 1 2 0 0 12 0 0 0 2.86E+08 2.22E+08 - - - 5.1734 0.9999 221125_WJC_METTL3_EV_vs_WT_F03.14788.14788.3 0.00446 13/36 R.SIHDALC[160.03]VIR.C "sp|P50991|TCPD_HUMAN,sp|P48643|TCPE_HUMAN,tr|E9PCA1|E9PCA1_HUMAN,tr|B7ZAR1|B7ZAR1_HUMAN,tr|E7ENZ3|E7ENZ3_HUMAN" 5 1182.6179 0.69 30401 14788 3 1182.617573 395.2133 T-complex protein 1 subunit delta OS=Homo sapiens OX=9606 GN=CCT4 PE=1 SV=4 6.46 2757.2 - 6.45E+06 - - - -0.2993 - 1.977 0.442 - 326.8 1 2 0 -0.0004 10 0 0 0 5.10E+08 7.43E+08 - - - 5.4583 0.9994 221125_WJC_METTL3_EV_vs_WT_F03.14789.14789.2 0.0509 16-Sep R.IDISPSTLR.K "sp|Q9NYF8|BCLF1_HUMAN,tr|E9PKI6|E9PKI6_HUMAN,tr|A0A1W2PQ43|A0A1W2PQ43_HUMAN,tr|E9PK91|E9PK91_HUMAN,tr|E9PK09|E9PK09_HUMAN,tr|E9PQN2|E9PQN2_HUMAN" 6 1000.5553 1.94 30402 14789 2 1000.554803 501.2849 Bcl-2-associated transcription factor 1 OS=Homo sapiens OX=9606 GN=BCLAF1 PE=1 SV=2 5.84 2757.2 - 3.93E+06 - - - -0.5067 - 1.912 0.264 - 238 1 2 0 -0.0005 9 0 0 0 1.58E+08 8.17E+07 - - - 2.8659 0.911 221125_WJC_METTL3_EV_vs_WT_F03.14790.14790.2 0.0148 14-Aug K.EQSIVEK[136.11]F.R "sp|Q86U44|MTA70_HUMAN,tr|H0YFV6|H0YFV6_HUMAN" 2 986.5164 0.69 30403 14790 2 986.51648 494.2655 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 4.53 2757.3 - 3.48E+06 - - - 0.0689 - 1.424 0.251 - 224.9 1 1 0 0.0001 8 0 0 0 6.75E+07 9.74E+07 - - - 1.9609 0.9996 221125_WJC_METTL3_EV_vs_WT_F03.14791.14791.2 0.0373 14-Oct K.TTLLHMLK.D "sp|Q9NR31|SAR1A_HUMAN,sp|Q9Y6B6|SAR1B_HUMAN,tr|D6RAA2|D6RAA2_HUMAN,tr|D6RD69|D6RD69_HUMAN,tr|X1WI22|X1WI22_HUMAN,tr|Q5SQT8|Q5SQT8_HUMAN,tr|D6RDB2|D6RDB2_HUMAN" 7 955.5525 1.09 30404 14791 2 955.552921 478.7835 GTP-binding protein SAR1a OS=Homo sapiens OX=9606 GN=SAR1A PE=1 SV=1 8.44 2757.4 - 3.20E+06 - - - 0.4688 - 1.806 0.339 - 361.6 1 2 0 0.0004 8 0 0 0 1.26E+08 1.15E+08 - - - 3.3275 0.997 221125_WJC_METTL3_EV_vs_WT_F03.14792.14792.2 0.152 14-Jul K.QLIDITGK[136.11].N "sp|Q14157|UBP2L_HUMAN,tr|Q5VU78|Q5VU78_HUMAN,tr|F8W726|F8W726_HUMAN,tr|Q5VU81|Q5VU81_HUMAN,tr|Q5VU79|Q5VU79_HUMAN,tr|Q5VU80|Q5VU80_HUMAN,tr|Q5VU77|Q5VU77_HUMAN" 7 894.5266 2.09 30405 14792 2 894.526595 448.2706 Ubiquitin-associated protein 2-like OS=Homo sapiens OX=9606 GN=UBAP2L PE=1 SV=2 5.84 2757.4 - 2.78E+06 - - - 0.0134 - 1.448 0.178 - 175.3 1 2 0 0 8 0 0 0 9.87E+08 4.73E+08 - - - 1.4722 1 221125_WJC_METTL3_EV_vs_WT_F03.14793.14793.2 2.32E-05 13/30 K.LIAPVAEEEATVPNNK[136.11].L "sp|P07195|LDHB_HUMAN,tr|A8MW50|A8MW50_HUMAN,tr|A0A3B3IS95|A0A3B3IS95_HUMAN,tr|C9J7H8|C9J7H8_HUMAN,tr|F5H793|F5H793_HUMAN,tr|A0A5F9ZHM4|A0A5F9ZHM4_HUMAN" 6 1701.9029 0.94 30406 14793 2 1701.902822 851.9587 L-lactate dehydrogenase B chain OS=Homo sapiens OX=9606 GN=LDHB PE=1 SV=2 4.25 2757.5 - 2.60E+06 - - - -0.0259 - 2.665 0.604 - 304.9 1 2 0 0 16 0 0 0 5.15E+07 5.48E+07 - - - 5.912 0.9997 221125_WJC_METTL3_EV_vs_WT_F03.14794.14794.2 6.78E-05 20-Sep R.NLPLPPPPPPR[166.11].G "sp|P61978|HNRPK_HUMAN,tr|Q5T6W2|Q5T6W2_HUMAN" 2 1203.7003 1.44 30407 14794 2 1203.700108 602.8575 Heterogeneous nuclear ribonucleoprotein K OS=Homo sapiens OX=9606 GN=HNRNPK PE=1 SV=1 9.75 2757.6 - 2.34E+06 - - - -0.1994 - 1.766 0.419 - 240 1 2 0 -0.0002 11 0 0 0 2.81E+08 1.96E+08 - - - 3.6742 0.9999 221125_WJC_METTL3_EV_vs_WT_F03.14795.14795.2 0.016 22-Dec R.LVGEIMQETGTR[166.11].L "sp|Q00341|VIGLN_HUMAN,tr|A0A024R4E5|A0A024R4E5_HUMAN,tr|H7C0A4|H7C0A4_HUMAN,tr|H0Y394|H0Y394_HUMAN" 4 1342.679 1.04 30408 14795 2 1342.67955 672.3468 Vigilin OS=Homo sapiens OX=9606 GN=HDLBP PE=1 SV=2 4.53 2757.7 - 1.35E+06 - - - 0.394 - 2.78 0.431 - 493.7 1 2 0 0.0005 12 0 0 0 6.96E+07 6.70E+07 - - - 4.9144 0.9381 221125_WJC_METTL3_EV_vs_WT_F03.14796.14796.2 0.00506 20-Oct L.FAVTVAPPGAR[166.11].Q "sp|Q00839|HNRPU_HUMAN,tr|A0A1W2PP35|A0A1W2PP35_HUMAN,tr|A0A1W2PPS1|A0A1W2PPS1_HUMAN,tr|A0A1W2PP22|A0A1W2PP22_HUMAN,tr|A0A1X7SBS1|A0A1X7SBS1_HUMAN" 5 1094.6112 0.34 30409 14796 2 1094.613326 548.3129 Heterogeneous nuclear ribonucleoprotein U OS=Homo sapiens OX=9606 GN=HNRNPU PE=1 SV=6 9.75 2757.8 - 894200 - - - 1.9432 - 1.634 0.362 - 282.7 1 1 0 0.0021 11 0 0 0 2.61E+07 7.77E+07 - - - 3.0424 0.9928 221125_WJC_METTL3_EV_vs_WT_F03.14798.14798.3 0.0858 13/36 R.TIR[166.11]YPDPLIK[136.11].V "sp|P62701|RS4X_HUMAN,sp|Q8TD47|RS4Y2_HUMAN" 2 1232.7248 14.02 30411 14798 3 1232.723539 411.9155 "40S ribosomal protein S4, X isoform OS=Homo sapiens OX=9606 GN=RPS4X PE=1 SV=2" 8.25 2758.1 - 861849 - - - -1.0059 - 1.904 0.231 - 210.6 1 2 1 -0.0012 10 0 0 0 1.81E+09 1.29E+08 - - - 2.9957 0.9999 221125_WJC_METTL3_EV_vs_WT_F03.14802.14802.2 3.18E-05 16/22 R.EIPETTPIEEVK.G "sp|Q71RC2|LARP4_HUMAN,tr|Q8TBL5|Q8TBL5_HUMAN,tr|A0A087WTL9|A0A087WTL9_HUMAN,tr|Q96J85|Q96J85_HUMAN" 4 1383.7133 2.27 30414 14802 2 1383.713542 692.8639 La-related protein 4 OS=Homo sapiens OX=9606 GN=LARP4 PE=1 SV=3 4.09 2758.6 - 3.27E+06 - - - 0.1554 - 2.641 0.494 - 918.7 1 2 0 0.0002 12 0 0 0 9.30E+07 4.10E+07 - - - 5.2449 0.9881 221125_WJC_METTL3_EV_vs_WT_F03.14803.14803.2 1.46 12-Jun R.DYLHYIR.K "sp|P62280|RS11_HUMAN,tr|M0R1H5|M0R1H5_HUMAN,tr|M0QZC5|M0QZC5_HUMAN" 3 978.4923 1.01 30415 14803 2 978.492653 490.2534 40S ribosomal protein S11 OS=Homo sapiens OX=9606 GN=RPS11 PE=1 SV=3 6.74 2758.6 - 742912 - - - 0.3444 - 1.129 0.15 - 121 1 2 0 0.0003 7 0 0 0 2.06E+08 2.04E+08 - - - 0.5332 0.9995 221125_WJC_METTL3_EV_vs_WT_F03.14804.14804.2 0.00649 14-Aug K.QYFEQFGK.V "sp|O43347|MSI1H_HUMAN,sp|Q96DH6|MSI2H_HUMAN,tr|B4DHE8|B4DHE8_HUMAN,tr|H0YHB7|H0YHB7_HUMAN,tr|A0A6Q8PF05|A0A6Q8PF05_HUMAN,tr|B4DM51|B4DM51_HUMAN,tr|J3KTC1|J3KTC1_HUMAN" 7 1045.4869 1.31 30416 14804 2 1045.486634 523.7507 RNA-binding protein Musashi homolog 1 OS=Homo sapiens OX=9606 GN=MSI1 PE=1 SV=1 6 2758.7 - 9.33E+06 - - - -0.2506 - 1.278 0.432 - 216.4 1 2 0 -0.0003 8 0 0 0 1.55E+09 1.18E+09 - - - 2.9715 0.9996 221125_WJC_METTL3_EV_vs_WT_F03.14805.14805.2 0.137 12-Jul K.DYSPYFK.T "sp|P02533|K1C14_HUMAN,sp|P08779|K1C16_HUMAN" 2 918.4123 19.4 30417 14805 2 918.412552 460.2134 "Keratin, type I cytoskeletal 14 OS=Homo sapiens OX=9606 GN=KRT14 PE=1 SV=4" 5.83 2758.7 - 6.37E+06 - - - 0.2374 - 1.362 0.425 - 182.6 1 2 0 0.0002 7 0 0 0 7.17E+08 3.70E+07 - - - 3.1589 0.9999 221125_WJC_METTL3_EV_vs_WT_F03.14806.14806.2 1.54E-06 24-Nov K.YVGVSSDSVGGFR[166.11].Y sp|Q14677|EPN4_HUMAN 1 1338.6444 1.47 30418 14806 2 1338.642521 670.3295 Clathrin interactor 1 OS=Homo sapiens OX=9606 GN=CLINT1 PE=1 SV=1 5.84 2758.8 - 3.37E+06 - - - -1.3663 - 2.302 0.58 - 313.4 1 2 0 -0.0018 13 0 0 0 7.68E+08 5.21E+08 - - - 5.4642 0.9974 221125_WJC_METTL3_EV_vs_WT_F03.14808.14808.2 0.111 16-Jul R.ESVESLIQK.H sp|Q9UMR3|TBX20_HUMAN 1 1031.5499 1.59 30420 14808 2 1031.551359 516.7822 T-box transcription factor TBX20 OS=Homo sapiens OX=9606 GN=TBX20 PE=1 SV=4 4.53 2759 - 1.38E+06 - - - 1.4241 - 1.466 0.266 - 151 2 2 0 0.0015 9 0 0 0 1.31E+07 8.21E+06 - - - 1.9774 0.9999 221125_WJC_METTL3_EV_vs_WT_F03.14810.14810.2 0.000198 14/24 R.AQAALAVNISAAR[166.11].G sp|P40227|TCPZ_HUMAN 1 1264.7127 0.36 30422 14810 2 1264.71419 633.3636 T-complex protein 1 subunit zeta OS=Homo sapiens OX=9606 GN=CCT6A PE=1 SV=3 9.79 2759.3 - 510323 - - - 1.175 - 2.89 0.49 - 807.5 1 2 0 0.0015 13 0 0 0 6.28E+06 1.73E+07 - - - 5.3834 1 221125_WJC_METTL3_EV_vs_WT_F03.14811.14811.2 2.58E-10 14/28 K.YMDTAGPAAEEFSSR.A sp|P31271|HXA13_HUMAN 1 1630.6933 2.07 30423 14811 2 1630.693555 816.3539 Homeobox protein Hox-A13 OS=Homo sapiens OX=9606 GN=HOXA13 PE=1 SV=3 4.14 2759.4 - 392684 - - - 0.1337 - 2.86 0.726 - 551.3 1 2 0 0.0002 15 0 0 0 1.52E+07 7.34E+06 - - - 6.9867 0.9997 221125_WJC_METTL3_EV_vs_WT_F03.14815.14815.2 0.00178 18-Dec R.SIHDALC[160.03]VIR[166.11].C "sp|P50991|TCPD_HUMAN,sp|P48643|TCPE_HUMAN,tr|E9PCA1|E9PCA1_HUMAN,tr|B7ZAR1|B7ZAR1_HUMAN,tr|E7ENZ3|E7ENZ3_HUMAN" 5 1192.6262 0.82 30425 14815 2 1192.626717 597.3204 T-complex protein 1 subunit delta OS=Homo sapiens OX=9606 GN=CCT4 PE=1 SV=4 6.46 2759.8 - 7.82E+06 - - - 0.436 - 1.846 0.408 - 480.9 1 2 0 0.0005 10 0 0 0 1.67E+08 2.05E+08 - - - 3.7655 0.9999 221125_WJC_METTL3_EV_vs_WT_F03.14816.14816.2 0.00012 20-Oct R.YGMSDVMPSGR.S "sp|Q14671|PUM1_HUMAN,tr|Q5T1Z8|Q5T1Z8_HUMAN,tr|H0YDK8|H0YDK8_HUMAN,tr|H0YEH2|H0YEH2_HUMAN,tr|Q5T1Z4|Q5T1Z4_HUMAN,tr|E9PR38|E9PR38_HUMAN" 6 1198.5111 1.73 30426 14816 2 1198.510904 600.2628 Pumilio homolog 1 OS=Homo sapiens OX=9606 GN=PUM1 PE=1 SV=3 5.84 2759.9 - 5.99E+06 - - - -0.146 - 1.78 0.631 - 350.2 1 2 0 -0.0002 11 0 0 0 1.79E+08 1.04E+08 - - - 5.2614 0.9998 221125_WJC_METTL3_EV_vs_WT_F03.14818.14818.2 0.00375 13/18 R.SIHDALC[160.03]VIR.C "sp|P50991|TCPD_HUMAN,sp|P48643|TCPE_HUMAN,tr|E9PCA1|E9PCA1_HUMAN,tr|B7ZAR1|B7ZAR1_HUMAN,tr|E7ENZ3|E7ENZ3_HUMAN" 5 1182.6179 0.82 30428 14818 2 1182.618399 592.3162 T-complex protein 1 subunit delta OS=Homo sapiens OX=9606 GN=CCT4 PE=1 SV=4 6.46 2760 - 4.70E+06 - - - 0.3991 - 2.043 0.389 - 586.9 1 2 0 0.0005 10 0 0 0 1.68E+08 2.05E+08 - - - 3.9082 0.9436 221125_WJC_METTL3_EV_vs_WT_F03.14819.14819.2 0.0393 12-Aug T.TLLHMLK.D "sp|Q9NR31|SAR1A_HUMAN,sp|Q9Y6B6|SAR1B_HUMAN,tr|D6RAA2|D6RAA2_HUMAN,tr|D6RD69|D6RD69_HUMAN,tr|X1WI22|X1WI22_HUMAN,tr|Q5SQT8|Q5SQT8_HUMAN,tr|D6RDB2|D6RDB2_HUMAN" 7 854.5048 1.2 30429 14819 2 854.505195 428.2597 GTP-binding protein SAR1a OS=Homo sapiens OX=9606 GN=SAR1A PE=1 SV=1 8.44 2760 - 3.41E+06 - - - 0.4681 - 1.468 0.296 - 225.2 1 1 0 0.0004 7 0 0 0 7.81E+07 6.49E+07 - - - 2.4435 1 221125_WJC_METTL3_EV_vs_WT_F03.14820.14820.3 1.64E-06 17/56 R.LEVSMVK[136.11]PTPGLTPR[166.11].F sp|Q53HL2|BOREA_HUMAN 1 1641.9243 1.94 30430 14820 3 1641.924797 548.3154 Borealin OS=Homo sapiens OX=9606 GN=CDCA8 PE=1 SV=2 8.75 2760.1 - 1.29E+06 - - - 0.313 - 2.619 0.452 - 341.7 1 2 0 0.0005 15 0 0 0 1.47E+08 7.57E+07 - - - 6.0915 0.9998 221125_WJC_METTL3_EV_vs_WT_F03.14821.14821.2 0.00114 18-Sep R.GQTSTYGFLK.F "sp|Q96T37|RBM15_HUMAN,tr|A0A494C001|A0A494C001_HUMAN,tr|A0A499FJY3|A0A499FJY3_HUMAN,tr|A0A087WWP4|A0A087WWP4_HUMAN" 4 1100.5502 1.44 30431 14821 2 1100.550629 551.2824 RNA-binding protein 15 OS=Homo sapiens OX=9606 GN=RBM15 PE=1 SV=2 8.59 2760.3 - 803882 - - - 0.3671 - 1.897 0.42 - 231.6 1 2 0 0.0004 10 0 0 0 2.48E+07 1.72E+07 - - - 3.9302 1 221125_WJC_METTL3_EV_vs_WT_F03.14823.14823.2 2.45E-08 24-Dec M.VFFTC[160.03]NAC[160.03]GESVK[136.11].K "sp|Q9NX58|LYAR_HUMAN,tr|D6RDJ1|D6RDJ1_HUMAN" 2 1525.6785 0.68 30433 14823 2 1525.681018 763.8465 Cell growth-regulating nucleolar protein OS=Homo sapiens OX=9606 GN=LYAR PE=1 SV=2 5.96 2760.5 - 509178 - - - 1.6596 - 2.444 0.708 - 361.9 1 2 0 0.0025 13 0 0 0 1.48E+07 2.16E+07 - - - 6.563 0.9994 221125_WJC_METTL3_EV_vs_WT_F03.14826.14826.2 0.00245 16-Aug R.FTILDSQGK[136.11].T sp|Q9NYU2|UGGG1_HUMAN 1 1015.543 0.17 30434 14826 2 1015.542163 508.7788 UDP-glucose:glycoprotein glucosyltransferase 1 OS=Homo sapiens OX=9606 GN=UGGT1 PE=1 SV=3 5.84 2760.9 - 3.16E+06 - - - -0.7858 - 1.675 0.334 - 244.8 1 2 0 -0.0008 9 0 0 0 1.96E+07 1.18E+08 - - - 2.9999 0.9997 221125_WJC_METTL3_EV_vs_WT_F03.14827.14827.3 0.00011 14/60 K.LIAPVAEEEATVPNNK.L "sp|P07195|LDHB_HUMAN,tr|A8MW50|A8MW50_HUMAN,tr|A0A3B3IS95|A0A3B3IS95_HUMAN,tr|C9J7H8|C9J7H8_HUMAN,tr|F5H793|F5H793_HUMAN,tr|A0A5F9ZHM4|A0A5F9ZHM4_HUMAN" 6 1693.8887 0.88 30435 14827 3 1693.887369 565.6368 L-lactate dehydrogenase B chain OS=Homo sapiens OX=9606 GN=LDHB PE=1 SV=2 4.25 2761 - 1.98E+06 - - - -0.7657 - 1.876 0.376 - 160.3 1 2 0 -0.0013 16 0 0 0 2.67E+07 3.04E+07 - - - 4.346 0.9999 221125_WJC_METTL3_EV_vs_WT_F03.14828.14828.3 0.000408 Nov-40 K.GLQEVGLPLHR[166.11].G sp|P11172|UMPS_HUMAN 1 1227.6963 0.01 30436 14828 3 1227.695731 410.2394 Uridine 5'-monophosphate synthase OS=Homo sapiens OX=9606 GN=UMPS PE=1 SV=1 6.75 2761.1 - 2.26E+06 - - - -0.4846 - 2.31 0.422 - 164 1 2 0 -0.0006 11 0 0 0 1.73E+05 3.43E+07 - - - 5.6232 0.9994 221125_WJC_METTL3_EV_vs_WT_F03.14829.14829.2 0.000441 28-Dec R.VTPEPGAGPTQGLLR[166.11].A "sp|Q86YP4|P66A_HUMAN,tr|V9GY85|V9GY85_HUMAN,tr|V9GYX5|V9GYX5_HUMAN,tr|C9JJK9|C9JJK9_HUMAN,tr|H7C3H1|H7C3H1_HUMAN,tr|C9JVY3|C9JVY3_HUMAN,tr|C9JMI3|C9JMI3_HUMAN,tr|C9JGN4|C9JGN4_HUMAN" 8 1501.8128 1.77 30437 14829 2 1501.813725 751.9137 Transcriptional repressor p66-alpha OS=Homo sapiens OX=9606 GN=GATAD2A PE=1 SV=1 5.97 2761.1 - 1.70E+06 - - - 0.6079 - 1.77 0.351 - 253.8 1 2 0 0.0009 15 0 0 0 8.58E+07 4.85E+07 - - - 3.037 0.9999 221125_WJC_METTL3_EV_vs_WT_F03.14830.14830.3 7.07E-05 16/60 K.LIAPVAEEEATVPNNK[136.11].L "sp|P07195|LDHB_HUMAN,tr|A8MW50|A8MW50_HUMAN,tr|A0A3B3IS95|A0A3B3IS95_HUMAN,tr|C9J7H8|C9J7H8_HUMAN,tr|F5H793|F5H793_HUMAN,tr|A0A5F9ZHM4|A0A5F9ZHM4_HUMAN" 6 1701.9029 0.9 30438 14830 3 1701.902045 568.3082 L-lactate dehydrogenase B chain OS=Homo sapiens OX=9606 GN=LDHB PE=1 SV=2 4.25 2761.3 - 1.57E+06 - - - -0.4824 - 2.334 0.392 - 226.4 1 2 0 -0.0008 16 0 0 0 2.67E+07 2.97E+07 - - - 5.085 0.9994 221125_WJC_METTL3_EV_vs_WT_F03.14833.14833.2 2.51E-07 24-Dec M.VFFTC[160.03]NAC[160.03]GESVK.K "sp|Q9NX58|LYAR_HUMAN,tr|D6RDJ1|D6RDJ1_HUMAN" 2 1517.6643 0.68 30441 14833 2 1517.668889 759.8394 Cell growth-regulating nucleolar protein OS=Homo sapiens OX=9606 GN=LYAR PE=1 SV=2 5.96 2761.6 - 481289 - - - 3.033 - 2.06 0.54 - 343.9 1 2 0 0.0046 13 0 0 0 1.48E+07 2.16E+07 - - - 4.8828 0.9999 221125_WJC_METTL3_EV_vs_WT_F03.14836.14836.3 0.000606 13/36 R.SIHDALC[160.03]VIR[166.11].C "sp|P50991|TCPD_HUMAN,sp|P48643|TCPE_HUMAN,tr|E9PCA1|E9PCA1_HUMAN,tr|B7ZAR1|B7ZAR1_HUMAN,tr|E7ENZ3|E7ENZ3_HUMAN" 5 1192.6262 0.69 30442 14836 3 1192.625725 398.5493 T-complex protein 1 subunit delta OS=Homo sapiens OX=9606 GN=CCT4 PE=1 SV=4 6.46 2762 - 4.41E+07 - - - -0.3958 - 2.298 0.442 - 354.1 1 2 0 -0.0005 10 0 0 0 5.10E+08 7.43E+08 - - - 5.8976 0.9999 221125_WJC_METTL3_EV_vs_WT_F03.14837.14837.2 2.16E-05 18-Nov R.TEMEDLMSSK.D sp|P35579|MYH9_HUMAN 1 1169.4944 0.96 30443 14837 2 1169.495048 585.7545 Myosin-9 OS=Homo sapiens OX=9606 GN=MYH9 PE=1 SV=4 4.14 2762 - 3.19E+06 - - - 0.5319 - 1.95 0.569 - 470.4 1 2 0 0.0006 10 0 0 0 6.02E+07 6.29E+07 - - - 5.1076 0.9997 221125_WJC_METTL3_EV_vs_WT_F03.14838.14838.2 0.216 18-Oct R.SINQPVAFVR[166.11].R "sp|Q9GZT3|SLIRP_HUMAN,tr|A0A087WUN7|A0A087WUN7_HUMAN,tr|H0YJI1|H0YJI1_HUMAN,tr|G3V2S9|G3V2S9_HUMAN,tr|H0YJ40|H0YJ40_HUMAN,tr|G3V4X6|G3V4X6_HUMAN" 6 1139.6327 1.26 30444 14838 2 1139.633031 570.8236 "SRA stem-loop-interacting RNA-binding protein, mitochondrial OS=Homo sapiens OX=9606 GN=SLIRP PE=1 SV=1" 9.47 2762.1 - 2.52E+06 - - - 0.3229 - 2.113 0.315 - 341.7 1 2 0 0.0004 10 0 0 0 1.55E+09 1.23E+09 - - - 3.4557 0.997 221125_WJC_METTL3_EV_vs_WT_F03.14839.14839.2 0.0439 14-Jul K.DIYQDLNR.L "sp|P43246|MSH2_HUMAN,tr|A0A2R8YG02|A0A2R8YG02_HUMAN,tr|A0A2R8Y7S8|A0A2R8Y7S8_HUMAN,tr|E9PHA6|E9PHA6_HUMAN,tr|A0A2R8YFH0|A0A2R8YFH0_HUMAN,tr|A0A2R8Y6P0|A0A2R8Y6P0_HUMAN" 6 1035.4985 999 30445 14839 2 1035.497216 518.7565 DNA mismatch repair protein Msh2 OS=Homo sapiens OX=9606 GN=MSH2 PE=1 SV=1 4.21 2762.1 - 2.00E+06 - - - -1.2622 - 1.293 0.255 - 182.4 1 2 0 -0.0013 8 0 0 0 1.73E+08 0.00E+00 - - - 1.699 0.9999 221125_WJC_METTL3_EV_vs_WT_F03.14840.14840.3 0.000589 13/40 R.LLTPTHSFLAR[166.11].S "sp|Q14244|MAP7_HUMAN,tr|A0A087WZ40|A0A087WZ40_HUMAN" 2 1264.7167 0.93 30446 14840 3 1264.715659 422.5795 Ensconsin OS=Homo sapiens OX=9606 GN=MAP7 PE=1 SV=1 9.76 2762.3 - 1.07E+06 - - - -0.8445 - 2.344 0.403 - 189.1 1 2 0 -0.0011 11 0 0 0 2.26E+07 2.44E+07 - - - 5.4527 0.9999 221125_WJC_METTL3_EV_vs_WT_F03.14841.14841.3 0.00018 Nov-40 R.LLTPTHSFLAR.S "sp|Q14244|MAP7_HUMAN,tr|A0A087WZ40|A0A087WZ40_HUMAN" 2 1254.7085 0.94 30447 14841 3 1254.704652 419.2434 Ensconsin OS=Homo sapiens OX=9606 GN=MAP7 PE=1 SV=1 9.76 2762.4 - 931759 - - - -3.0326 - 2.531 0.45 - 244.5 1 2 0 -0.0038 11 0 0 0 2.28E+07 2.42E+07 - - - 6.194 0.9791 221125_WJC_METTL3_EV_vs_WT_F03.14842.14842.2 0.646 16-Jul K.TDLDAMDIK.G sp|Q96JM3|CHAP1_HUMAN 1 1020.4798 0.98 30448 14842 2 1020.477855 511.2472 Chromosome alignment-maintaining phosphoprotein 1 OS=Homo sapiens OX=9606 GN=CHAMP1 PE=1 SV=2 3.93 2762.5 - 428484 - - - -1.8687 - 1.212 0.132 - 98.1 1 2 0 -0.0019 9 0 0 0 5.10E+06 5.19E+06 - - - 0.5716 0.9998 221125_WJC_METTL3_EV_vs_WT_F03.14846.14846.2 0.000192 18-Sep R.TEMEDLMSSK[136.11].D sp|P35579|MYH9_HUMAN 1 1177.5086 0.96 30450 14846 2 1177.508588 589.7616 Myosin-9 OS=Homo sapiens OX=9606 GN=MYH9 PE=1 SV=4 4.14 2763 - 3.46E+06 - - - -0.0323 - 1.879 0.44 - 320.8 1 2 0 0 10 0 0 0 6.02E+07 6.29E+07 - - - 4.0514 0.9999 221125_WJC_METTL3_EV_vs_WT_F03.14848.14848.2 5.87E-05 13/26 R.TALINSTGEEVAMR.K "sp|P02545|LMNA_HUMAN,tr|Q5TCI8|Q5TCI8_HUMAN,tr|A0A6Q8PFJ0|A0A6Q8PFJ0_HUMAN,tr|Q3BDU5|Q3BDU5_HUMAN" 4 1490.7399 7.97 30452 14848 2 1490.738952 746.3772 Prelamin-A\C OS=Homo sapiens OX=9606 GN=LMNA PE=1 SV=1 4.53 2763.2 - 1.94E+06 - - - -0.6312 - 2.475 0.503 - 475.8 1 2 0 -0.0009 14 0 0 0 3.26E+07 4.09E+06 - - - 5.03 1 221125_WJC_METTL3_EV_vs_WT_F03.14855.14855.3 0.000123 15/36 K.FELAVDAVHR[166.11].K "sp|Q8WWM7|ATX2L_HUMAN,tr|H3BSQ5|H3BSQ5_HUMAN,tr|H3BSK9|H3BSK9_HUMAN,tr|H3BUE3|H3BUE3_HUMAN,tr|H3BUF6|H3BUF6_HUMAN" 5 1165.6119 1.48 30457 14855 3 1165.611173 389.5446 Ataxin-2-like protein OS=Homo sapiens OX=9606 GN=ATXN2L PE=1 SV=2 5.32 2764 - 4.82E+06 - - - -0.6469 - 2.64 0.462 - 323 1 2 0 -0.0008 10 0 0 0 1.25E+08 8.41E+07 - - - 6.5257 0.9968 221125_WJC_METTL3_EV_vs_WT_F03.14856.14856.2 0.0977 18-Dec K.WEAEPVYVQR.A "sp|P25311|ZA2G_HUMAN,tr|C9JEV0|C9JEV0_HUMAN" 2 1275.6248 999 30458 14856 2 1275.620377 638.8197 Zinc-alpha-2-glycoprotein OS=Homo sapiens OX=9606 GN=AZGP1 PE=1 SV=2 4.53 2764.1 - 1.08E+06 - - - -3.4571 - 1.989 0.276 - 599.2 1 2 0 -0.0044 10 0 0 0 8.21E+07 0.00E+00 - - - 2.9975 0.9989 221125_WJC_METTL3_EV_vs_WT_F03.14858.14858.2 0.0013 16-Nov K.EGLPVALDK.H sp|Q9Y224|RTRAF_HUMAN 1 940.5229 1.15 30460 14858 2 940.520364 471.2687 "RNA transcription, translation and transport factor protein OS=Homo sapiens OX=9606 GN=RTRAF PE=1 SV=1" 4.37 2764.3 - 876922 - - - -2.7463 - 1.854 0.371 - 302.7 1 2 0 -0.0026 9 0 0 0 1.71E+07 1.49E+07 - - - 3.5664 0.9904 221125_WJC_METTL3_EV_vs_WT_F03.14859.14859.2 0.296 14-Aug K.SILEIMHK[136.11].E sp|O00425|IF2B3_HUMAN 1 977.5459 1.39 30461 14859 2 977.545426 489.7802 Insulin-like growth factor 2 mRNA-binding protein 3 OS=Homo sapiens OX=9606 GN=IGF2BP3 PE=1 SV=2 6.47 2764.5 - 460113 - - - -0.5238 - 1.247 0.13 - 174.1 1 2 0 -0.0005 8 0 0 0 2.73E+07 1.97E+07 - - - 0.6668 0.9999 221125_WJC_METTL3_EV_vs_WT_F03.14861.14861.2 3.60E-06 20-Nov R.NPEAALSPTFR[166.11].S "sp|Q86U44|MTA70_HUMAN,tr|B4E349|B4E349_HUMAN,tr|F5H6D8|F5H6D8_HUMAN,tr|B4DTN4|B4DTN4_HUMAN" 4 1211.6174 0.03 30462 14861 2 1211.617668 606.816 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 6 2764.7 - 2.04E+07 - - - 0.2154 - 2.496 0.567 - 677.5 1 2 0 0.0003 11 0 0 0 1.69E+07 5.64E+08 - - - 5.7032 0.9985 221125_WJC_METTL3_EV_vs_WT_F03.14864.14864.3 3.01E-09 17/56 K.ASEVMGPVEAAPEYR.V "sp|Q8WWY3|PRP31_HUMAN,tr|E7EVX8|E7EVX8_HUMAN,tr|E7EU94|E7EU94_HUMAN,tr|E7ESX0|E7ESX0_HUMAN,tr|E7EN72|E7EN72_HUMAN" 5 1604.7505 2.35 30464 14864 3 1604.738171 535.9241 U4\U6 small nuclear ribonucleoprotein Prp31 OS=Homo sapiens OX=9606 GN=PRPF31 PE=1 SV=2 4.25 2765 - 1.38E+06 - - - -7.6566 - 2.984 0.538 - 442.2 1 2 0 -0.0123 15 0 0 0 3.00E+07 1.27E+07 - - - 7.3875 0.9888 221125_WJC_METTL3_EV_vs_WT_F03.14865.14865.2 0.00027 22-Sep K.EGWPSSAYGVTK[136.11].L sp|P16152|CBR1_HUMAN 1 1288.6179 0.7 30465 14865 2 1288.615858 645.3162 Carbonyl reductase [NADPH] 1 OS=Homo sapiens OX=9606 GN=CBR1 PE=1 SV=3 6.1 2765.1 - 2.61E+06 - - - -1.5978 - 1.576 0.087 - 156.7 1 2 0 -0.0021 12 0 0 0 6.05E+07 8.63E+07 - - - 0.8798 0.9641 221125_WJC_METTL3_EV_vs_WT_F03.14866.14866.2 0.00529 18-Sep S.ALEEQLQQIR.A "sp|P13645|K1C10_HUMAN,tr|A0A1B0GVI3|A0A1B0GVI3_HUMAN" 2 1226.6619 999 30466 14866 2 1226.664413 614.3382 "Keratin, type I cytoskeletal 10 OS=Homo sapiens OX=9606 GN=KRT10 PE=1 SV=6" 4.53 2765.1 - 2.15E+06 - - - 2.0486 - 2.063 0.364 - 351.7 1 1 0 0.0025 10 0 0 0 2.88E+08 0.00E+00 - - - 3.7501 0.9993 221125_WJC_METTL3_EV_vs_WT_F03.14868.14868.2 0.000613 18-Oct K.C[160.03]LVSGWGTTK.S "sp|Q9Y337|KLK5_HUMAN,tr|M0QXX2|M0QXX2_HUMAN" 2 1107.5383 19.18 30468 14868 2 1107.536758 554.7764 Kallikrein-5 OS=Homo sapiens OX=9606 GN=KLK5 PE=1 SV=3 8.22 2765.3 - 1.85E+06 - - - -1.3742 - 1.74 0.331 - 287.8 1 2 0 -0.0015 10 0 0 0 2.88E+07 1.50E+06 - - - 3.0313 0.9997 221125_WJC_METTL3_EV_vs_WT_F03.14869.14869.2 0.00095 16-Sep K.EGLPVALDK[136.11].H sp|Q9Y224|RTRAF_HUMAN 1 948.5371 1.15 30469 14869 2 948.538241 475.2758 "RNA transcription, translation and transport factor protein OS=Homo sapiens OX=9606 GN=RTRAF PE=1 SV=1" 4.37 2765.4 - 743684 - - - 1.1534 - 1.789 0.431 - 201.9 1 2 0 0.0011 9 0 0 0 1.71E+07 1.49E+07 - - - 3.9068 0.8605 221125_WJC_METTL3_EV_vs_WT_F03.14870.14870.3 0.0078 Oct-44 V.RLLADPTGAFGK.E sp|P30044|PRDX5_HUMAN 1 1244.6877 0.45 30470 14870 3 1244.686555 415.9032 "Peroxiredoxin-5, mitochondrial OS=Homo sapiens OX=9606 GN=PRDX5 PE=1 SV=4" 8.75 2765.5 - 651964 - - - -0.9368 - 1.925 0.238 - 139.6 1 1 0 -0.0012 12 0 0 0 9.90E+06 2.19E+07 - - - 3.0085 0.9998 221125_WJC_METTL3_EV_vs_WT_F03.14874.14874.2 8.18E-05 18-Nov K.YAQAGFEGFK.T "sp|O75643|U520_HUMAN,tr|A0A494C1A5|A0A494C1A5_HUMAN" 2 1116.524 1.88 30472 14874 2 1116.522901 559.2693 U5 small nuclear ribonucleoprotein 200 kDa helicase OS=Homo sapiens OX=9606 GN=SNRNP200 PE=1 SV=2 6 2766 - 4.94E+06 - - - -0.9933 - 2.105 0.488 - 337.9 1 2 0 -0.0011 10 0 0 0 1.40E+08 7.46E+07 - - - 4.7226 0.999 221125_WJC_METTL3_EV_vs_WT_F03.14876.14876.2 0.0565 20-Aug R.NLPLPPPPPPR.G "sp|P61978|HNRPK_HUMAN,tr|Q5T6W2|Q5T6W2_HUMAN" 2 1193.6921 1.44 30474 14876 2 1193.691894 597.8533 Heterogeneous nuclear ribonucleoprotein K OS=Homo sapiens OX=9606 GN=HNRNPK PE=1 SV=1 9.75 2766.1 - 5.71E+06 - - - -0.1541 - 1.429 0.314 - 197.5 1 2 0 -0.0002 11 0 0 0 2.56E+08 1.77E+08 - - - 2.3258 0.9884 221125_WJC_METTL3_EV_vs_WT_F03.14878.14878.2 0.0291 14-Aug K.TIIGDFQK[136.11].E sp|Q96A49|SYAP1_HUMAN 1 928.5109 1.31 30476 14878 2 928.511394 465.2627 Synapse-associated protein 1 OS=Homo sapiens OX=9606 GN=SYAP1 PE=1 SV=1 5.5 2766.3 - 1.19E+06 - - - 0.4965 - 1.303 0.1 - 176.5 1 2 0 0.0005 8 0 0 0 5.95E+07 4.56E+07 - - - 0.5777 1 221125_WJC_METTL3_EV_vs_WT_F03.14884.14884.3 4.94E-05 14/56 R.LEVSMVKPTPGLTPR.F sp|Q53HL2|BOREA_HUMAN 1 1623.9018 1.91 30480 14884 3 1623.902609 542.3079 Borealin OS=Homo sapiens OX=9606 GN=CDCA8 PE=1 SV=2 8.75 2767 - 4.65E+06 - - - 0.4902 - 2.35 0.499 - 191 1 2 0 0.0008 15 0 0 0 1.43E+08 7.50E+07 - - - 6.3326 0.9198 221125_WJC_METTL3_EV_vs_WT_F03.14890.14890.2 0.0415 20-May K.ELPVNAQNYVR[166.11].F sp|P30520|PURA2_HUMAN 1 1311.6811 4.31 30486 14890 2 1311.687444 656.8478 Adenylosuccinate synthetase isozyme 2 OS=Homo sapiens OX=9606 GN=ADSS2 PE=1 SV=3 6.1 2767.6 - 859590 - - - 4.8594 - 1.577 0.204 - 59.1 29 2 0 0.0064 11 0 0 0 4.10E+07 9.51E+06 - - - 1.1248 0.9985 221125_WJC_METTL3_EV_vs_WT_F03.14891.14891.3 0.0226 Oct-48 R.ILHLQGEGDIVPK.L sp|O95235|KI20A_HUMAN 1 1417.7929 1.44 30487 14891 3 1417.793436 473.6049 Kinesin-like protein KIF20A OS=Homo sapiens OX=9606 GN=KIF20A PE=1 SV=1 5.32 2767.7 - 725303 - - - 0.3675 - 1.661 0.277 - 115 1 2 0 0.0005 13 0 0 0 9.08E+06 6.28E+06 - - - 3.0039 0.9999 221125_WJC_METTL3_EV_vs_WT_F03.14894.14894.3 5.10E-05 13/52 K.MVDPEK[136.11]PQLGMIDR[166.11].W "sp|P09874|PARP1_HUMAN,tr|A0A7I2V5E9|A0A7I2V5E9_HUMAN,tr|A0A7I2V625|A0A7I2V625_HUMAN,tr|A0A7I2V3E1|A0A7I2V3E1_HUMAN" 4 1645.8287 0.96 30488 14894 3 1645.829142 549.6168 Poly [ADP-ribose] polymerase 1 OS=Homo sapiens OX=9606 GN=PARP1 PE=1 SV=4 4.56 2768.1 - 3.03E+06 - - - 0.288 - 2.009 0.471 - 154.2 1 2 0 0.0005 14 0 0 0 5.55E+07 5.77E+07 - - - 5.645 0.9997 221125_WJC_METTL3_EV_vs_WT_F03.14896.14896.3 0.00924 17/40 R.INEILSNALKR.G "sp|P52272|HNRPM_HUMAN,tr|M0R019|M0R019_HUMAN,tr|A0A087X0X3|A0A087X0X3_HUMAN" 3 1269.7405 1.66 30490 14896 3 1269.741037 424.2541 Heterogeneous nuclear ribonucleoprotein M OS=Homo sapiens OX=9606 GN=HNRNPM PE=1 SV=3 8.75 2768.3 - 1.82E+06 - - - 0.4347 - 2.637 0.267 - 644.8 1 2 0 0.0006 11 0 0 0 5.23E+07 3.15E+07 - - - 4.2712 0.9998 221125_WJC_METTL3_EV_vs_WT_F03.14899.14899.2 2.37E-08 20-Nov K.YDSDGVWDPEK.W "sp|Q9NRA8|4ET_HUMAN,tr|B1AKL5|B1AKL5_HUMAN,tr|B1AKL4|B1AKL4_HUMAN" 3 1309.5463 1.61 30493 14899 2 1309.543367 655.7804 Eukaryotic translation initiation factor 4E transporter OS=Homo sapiens OX=9606 GN=EIF4ENIF1 PE=1 SV=2 3.84 2768.7 - 531845 - - - -2.2107 - 1.926 0.643 - 300.8 1 2 0 -0.0029 11 0 0 0 8.90E+06 5.54E+06 - - - 5.5624 0.9994 221125_WJC_METTL3_EV_vs_WT_F03.14900.14900.2 0.000497 20-Oct K.TIDLC[160.03]NNPMTK[136.11].E "sp|Q9NYU2|UGGG1_HUMAN,tr|H7BZG0|H7BZG0_HUMAN" 2 1313.6199 0.33 30494 14900 2 1313.621287 657.8172 UDP-glucose:glycoprotein glucosyltransferase 1 OS=Homo sapiens OX=9606 GN=UGGT1 PE=1 SV=3 5.5 2768.8 - 520120 - - - 1.0498 - 1.766 0.353 - 232.9 1 2 0 0.0014 11 0 0 0 5.65E+06 1.71E+07 - - - 3.1863 1 221125_WJC_METTL3_EV_vs_WT_F03.14901.14901.2 2.36E-07 28-Sep K.YMDTAGPAAEEFSSR[166.11].A sp|P31271|HXA13_HUMAN 1 1640.7016 2.07 30495 14901 2 1640.701602 821.3581 Homeobox protein Hox-A13 OS=Homo sapiens OX=9606 GN=HOXA13 PE=1 SV=3 4.14 2768.9 - 247901 - - - -0.003 - 2.262 0.693 - 247.5 1 2 0 0 15 0 0 0 1.52E+07 7.34E+06 - - - 6.1663 0.9999 221125_WJC_METTL3_EV_vs_WT_F03.14903.14903.3 0.000206 Dec-40 R.AVFPSIVGRPR.Q "sp|Q6S8J3|POTEE_HUMAN,sp|P63261|ACTG_HUMAN,sp|P68133|ACTS_HUMAN,sp|P62736|ACTA_HUMAN,sp|Q9BYX7|ACTBM_HUMAN,sp|P68032|ACTC_HUMAN,sp|P60709|ACTB_HUMAN,sp|P63267|ACTH_HUMAN,sp|A5A3E0|POTEF_HUMAN,sp|P0CG38|POTEI_HUMAN,tr|A0A804GS07|A0A804GS07_HUMAN,tr|I3L3I0|I3L3I0_HUMAN,tr|G5E9R0|G5E9R0_HUMAN,tr|E7EVS6|E7EVS6_HUMAN,tr|B8ZZJ2|B8ZZJ2_HUMAN,tr|J3KT65|J3KT65_HUMAN,tr|I3L3R2|I3L3R2_HUMAN,tr|K7EM38|K7EM38_HUMAN,tr|F6QUT6|F6QUT6_HUMAN,tr|C9JTX5|C9JTX5_HUMAN,tr|A0A6Q8PH58|A0A6Q8PH58_HUMAN,tr|F6UVQ4|F6UVQ4_HUMAN,tr|F8WB63|F8WB63_HUMAN,tr|I3L1U9|I3L1U9_HUMAN,tr|A0A2R8Y793|A0A2R8Y793_HUMAN,tr|I3L4N8|I3L4N8_HUMAN,tr|C9JUM1|C9JUM1_HUMAN,tr|F8WCH0|F8WCH0_HUMAN,tr|C9JZR7|C9JZR7_HUMAN,tr|C9JFL5|C9JFL5_HUMAN,tr|A0A2R8YGF8|A0A2R8YGF8_HUMAN,tr|A6NL76|A6NL76_HUMAN" 32 1197.6982 0.94 30496 14903 3 1197.699756 400.24 POTE ankyrin domain family member E OS=Homo sapiens OX=9606 GN=POTEE PE=2 SV=3 12 2769.1 - 3.02E+06 - - - 1.2775 - 2.531 0.411 - 234.7 1 2 0 0.0015 11 0 0 0 1.66E+09 1.76E+09 - - - 5.7599 0.9996 221125_WJC_METTL3_EV_vs_WT_F03.14905.14905.3 0.00102 13/36 R.TIRYPDPLIK.V "sp|P62701|RS4X_HUMAN,sp|Q8TD47|RS4Y2_HUMAN" 2 1214.7023 12.44 30497 14905 3 1214.70242 405.908 "40S ribosomal protein S4, X isoform OS=Homo sapiens OX=9606 GN=RPS4X PE=1 SV=2" 8.25 2769.4 - 4.48E+06 - - - 0.0914 - 2.201 0.402 - 267 1 2 1 0.0001 10 0 0 0 1.11E+09 8.94E+07 - - - 5.3258 0.9999 221125_WJC_METTL3_EV_vs_WT_F03.14907.14907.3 0.000129 Dec-52 K.MVDPEKPQLGMIDR.W "sp|P09874|PARP1_HUMAN,tr|A0A7I2V5E9|A0A7I2V5E9_HUMAN,tr|A0A7I2V625|A0A7I2V625_HUMAN,tr|A0A7I2V3E1|A0A7I2V3E1_HUMAN" 4 1627.8062 0.96 30499 14907 3 1627.806633 543.6093 Poly [ADP-ribose] polymerase 1 OS=Homo sapiens OX=9606 GN=PARP1 PE=1 SV=4 4.56 2769.4 - 3.01E+06 - - - 0.2672 - 2.105 0.477 - 144.8 1 2 0 0.0004 14 0 0 0 5.55E+07 5.77E+07 - - - 5.836 0.9937 221125_WJC_METTL3_EV_vs_WT_F03.14908.14908.2 0.000422 22-Dec K.EGWPSSAYGVTK.L sp|P16152|CBR1_HUMAN 1 1280.6037 0.54 30500 14908 2 1280.596769 641.3091 Carbonyl reductase [NADPH] 1 OS=Homo sapiens OX=9606 GN=CBR1 PE=1 SV=3 6.1 2769.5 - 1.53E+06 - - - -5.4256 - 1.533 0.497 - 299 1 2 0 -0.0069 12 0 0 0 3.86E+07 7.14E+07 - - - 3.8338 0.9999 221125_WJC_METTL3_EV_vs_WT_F03.14909.14909.3 0.000274 14/44 R.VGHSELVGEIIR.L "sp|P38606|VATA_HUMAN,tr|C9JA17|C9JA17_HUMAN,tr|C9JVW8|C9JVW8_HUMAN" 3 1307.7197 1.08 30501 14909 3 1307.718395 436.9139 V-type proton ATPase catalytic subunit A OS=Homo sapiens OX=9606 GN=ATP6V1A PE=1 SV=2 5.4 2769.6 - 1.42E+06 - - - -1.0362 - 2.529 0.392 - 294.6 1 2 0 -0.0014 12 0 0 0 1.97E+07 1.83E+07 - - - 5.4818 0.9967 221125_WJC_METTL3_EV_vs_WT_F03.14910.14910.3 0.0291 Sep-44 R.VGHSELVGEIIR[166.11].L "sp|P38606|VATA_HUMAN,tr|C9JA17|C9JA17_HUMAN,tr|C9JVW8|C9JVW8_HUMAN" 3 1317.728 1.12 30502 14910 3 1317.729437 440.2499 V-type proton ATPase catalytic subunit A OS=Homo sapiens OX=9606 GN=ATP6V1A PE=1 SV=2 5.4 2769.7 - 1.12E+06 - - - 1.0753 - 1.795 0.218 - 117.1 1 2 0 0.0014 12 0 0 0 2.04E+07 1.83E+07 - - - 2.5916 0.9993 221125_WJC_METTL3_EV_vs_WT_F03.14911.14911.2 0.692 16-Oct R.KFVADGIFK.A "sp|P23396|RS3_HUMAN,tr|E9PL09|E9PL09_HUMAN,tr|E9PK82|E9PK82_HUMAN,tr|F2Z2S8|F2Z2S8_HUMAN,tr|H0YCJ7|H0YCJ7_HUMAN,tr|E9PQ96|E9PQ96_HUMAN,tr|E9PJH4|E9PJH4_HUMAN,tr|E9PQX2|E9PQX2_HUMAN,tr|E9PPU1|E9PPU1_HUMAN" 9 1023.5753 0.74 30503 14911 2 1023.574709 512.7949 40S ribosomal protein S3 OS=Homo sapiens OX=9606 GN=RPS3 PE=1 SV=2 8.59 2769.9 - 718632 - - - -0.594 - 2.079 0.214 - 316.5 1 2 0 -0.0006 9 0 0 0 8.25E+07 1.11E+08 - - - 2.7388 0.9999 221125_WJC_METTL3_EV_vs_WT_F03.14913.14913.3 0.000215 16/40 R.NLPLPPPPPPR[166.11].G "sp|P61978|HNRPK_HUMAN,tr|Q5T6W2|Q5T6W2_HUMAN" 2 1203.7003 1.24 30505 14913 3 1203.69656 402.2407 Heterogeneous nuclear ribonucleoprotein K OS=Homo sapiens OX=9606 GN=HNRNPK PE=1 SV=1 9.75 2770.1 - 621234 - - - -3.147 - 3.081 0.432 - 440.9 1 2 0 -0.0038 11 0 0 0 2.07E+07 1.67E+07 - - - 6.552 0.9994 221125_WJC_METTL3_EV_vs_WT_F03.14914.14914.3 0.00344 13/36 R.SINQPVAFVR[166.11].R "sp|Q9GZT3|SLIRP_HUMAN,tr|A0A087WUN7|A0A087WUN7_HUMAN,tr|H0YJI1|H0YJI1_HUMAN,tr|G3V2S9|G3V2S9_HUMAN,tr|H0YJ40|H0YJ40_HUMAN,tr|G3V4X6|G3V4X6_HUMAN" 6 1139.6327 0.001 30506 14914 3 1139.632509 380.8848 "SRA stem-loop-interacting RNA-binding protein, mitochondrial OS=Homo sapiens OX=9606 GN=SLIRP PE=1 SV=1" 9.47 2770.3 - 511826 - - - -0.1351 - 1.527 0.355 - 243 1 2 0 -0.0002 10 0 0 0 0.00E+00 1.06E+07 - - - 3.7341 0.996 221125_WJC_METTL3_EV_vs_WT_F03.14915.14915.3 0.0314 14/36 K.IDR[166.11]EISAILK[136.11].Y sp|Q96DG6|CMBL_HUMAN 1 1174.704 0.95 30507 14915 3 1174.705018 392.5753 Carboxymethylenebutenolidase homolog OS=Homo sapiens OX=9606 GN=CMBL PE=1 SV=1 6.07 2770.4 - 443164 - - - 0.83 - 2.258 0.225 - 164.3 1 2 1 0.001 10 0 0 0 9.04E+06 9.48E+06 - - - 3.4269 0.9998 221125_WJC_METTL3_EV_vs_WT_F03.14919.14919.3 0.00523 Dec-40 R.INEILSNALK[136.11]R[166.11].G "sp|P52272|HNRPM_HUMAN,tr|M0R019|M0R019_HUMAN,tr|A0A087X0X3|A0A087X0X3_HUMAN" 3 1287.763 1.63 30509 14919 3 1287.763164 430.2616 Heterogeneous nuclear ribonucleoprotein M OS=Homo sapiens OX=9606 GN=HNRNPM PE=1 SV=3 8.75 2770.9 - 1.97E+06 - - - 0.1623 - 2.436 0.319 - 257.3 1 2 0 0.0002 11 0 0 0 5.29E+07 3.25E+07 - - - 4.6258 0.9997 221125_WJC_METTL3_EV_vs_WT_F03.14920.14920.2 0.000267 12-Jul K.AWEDYYK.K sp|Q96I24|FUBP3_HUMAN 1 973.4181 1.77 30510 14920 2 973.418772 487.7164 Far upstream element-binding protein 3 OS=Homo sapiens OX=9606 GN=FUBP3 PE=1 SV=2 4.37 2770.9 - 2.62E+06 - - - 0.641 - 1.564 0.457 - 297.5 1 2 0 0.0006 7 0 0 0 6.95E+07 3.92E+07 - - - 3.8333 0.9969 221125_WJC_METTL3_EV_vs_WT_F03.14923.14923.2 0.115 12-May K.AWEDYYK[136.11].K sp|Q96I24|FUBP3_HUMAN 1 981.4323 1.82 30513 14923 2 981.432933 491.7235 Far upstream element-binding protein 3 OS=Homo sapiens OX=9606 GN=FUBP3 PE=1 SV=2 4.37 2771.1 - 1.75E+06 - - - 0.5961 - 1.072 0.309 - 116.7 1 2 0 0.0006 7 0 0 0 6.85E+07 3.77E+07 - - - 1.5434 0.9983 221125_WJC_METTL3_EV_vs_WT_F03.14924.14924.2 0.0681 16-Aug R.YLDVSILGK[136.11].F sp|Q86U44|MTA70_HUMAN 1 1014.5841 0.04 30514 14924 2 1014.58561 508.2993 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 5.83 2771.2 - 1.53E+06 - - - 1.4903 - 1.335 0.339 - 130.5 1 2 0 0.0015 9 0 0 0 1.04E+06 2.33E+07 - - - 2.3803 0.9998 221125_WJC_METTL3_EV_vs_WT_F03.14925.14925.2 2.78E-05 18-Nov R.SGYFALGNEK[136.11].G sp|Q9Y5J1|UTP18_HUMAN 1 1092.5331 1.01 30515 14925 2 1092.534319 547.2738 U3 small nucleolar RNA-associated protein 18 homolog OS=Homo sapiens OX=9606 GN=UTP18 PE=1 SV=3 5.72 2771.3 - 1.27E+06 - - - 1.0929 - 1.911 0.469 - 280.7 1 2 0 0.0012 10 0 0 0 2.21E+07 2.19E+07 - - - 4.3124 0.9985 221125_WJC_METTL3_EV_vs_WT_F03.14926.14926.3 0.00114 Oct-40 R.LETHMTPEMFR[166.11].T sp|Q08211|DHX9_HUMAN 1 1400.6456 1.04 30516 14926 3 1400.651734 467.8891 ATP-dependent RNA helicase A OS=Homo sapiens OX=9606 GN=DHX9 PE=1 SV=4 5.4 2771.4 - 811697 - - - 4.3708 - 2.055 0.383 - 181.6 1 2 0 0.0061 11 0 0 0 7.20E+07 6.95E+07 - - - 4.8546 0.9995 221125_WJC_METTL3_EV_vs_WT_F03.14927.14927.2 0.000251 13/24 K.ALQALQNEPIPER.S "sp|Q9NUL3|STAU2_HUMAN,tr|E5RJN7|E5RJN7_HUMAN,tr|E7EVJ4|E7EVJ4_HUMAN,tr|E7EVI1|E7EVI1_HUMAN,tr|E7EPX0|E7EPX0_HUMAN,tr|E5RFK1|E5RFK1_HUMAN" 6 1477.7889 2.17 30517 14927 2 1477.791919 739.9017 Double-stranded RNA-binding protein Staufen homolog 2 OS=Homo sapiens OX=9606 GN=STAU2 PE=1 SV=2 4.53 2771.5 - 423030 - - - 2.0483 - 2.664 0.318 - 784.5 1 2 0 0.003 13 0 0 0 1.57E+07 7.22E+06 - - - 3.9036 0.985 221125_WJC_METTL3_EV_vs_WT_F03.14928.14928.3 0.137 Nov-48 K.MEIATK[136.11]DPLNPIK[136.11].Q "sp|Q15181|IPYR_HUMAN,tr|Q5SQT6|Q5SQT6_HUMAN" 2 1484.8244 0.63 30518 14928 3 1484.823156 495.9487 Inorganic pyrophosphatase OS=Homo sapiens OX=9606 GN=PPA1 PE=1 SV=2 5.82 2771.6 - 351317 - - - -0.8048 - 2.023 0.184 - 133.3 1 2 1 -0.0012 13 0 0 0 4.81E+06 7.62E+06 - - - 2.5014 0.9999 221125_WJC_METTL3_EV_vs_WT_F03.14931.14931.2 0.000165 18-Nov K.SQAFIEMETR[166.11].E "sp|P43243|MATR3_HUMAN,tr|B3KM87|B3KM87_HUMAN,tr|A8MXP9|A8MXP9_HUMAN,tr|A0A0R4J2E8|A0A0R4J2E8_HUMAN,tr|H0Y8T4|H0Y8T4_HUMAN,tr|D6REM6|D6REM6_HUMAN" 6 1220.5735 1.22 30519 14931 2 1220.574176 611.294 Matrin-3 OS=Homo sapiens OX=9606 GN=MATR3 PE=1 SV=2 4.53 2772 - 7.88E+06 - - - 0.5596 - 2.281 0.531 - 533.9 1 2 0 0.0007 10 0 0 0 3.40E+09 2.79E+09 - - - 5.2645 0.9999 221125_WJC_METTL3_EV_vs_WT_F03.14932.14932.3 6.85E-06 13/40 R.LETHMTPEMFR.T sp|Q08211|DHX9_HUMAN 1 1390.6373 1.04 30520 14932 3 1390.638348 464.5531 ATP-dependent RNA helicase A OS=Homo sapiens OX=9606 GN=DHX9 PE=1 SV=4 5.4 2772.1 - 909710 - - - 0.7234 - 2.169 0.462 - 299.6 1 2 0 0.001 11 0 0 0 7.20E+07 6.95E+07 - - - 5.8901 0.9816 221125_WJC_METTL3_EV_vs_WT_F03.14933.14933.2 0.00222 16-Sep D.VSVVDLTC[160.03]R.L "sp|O14556|G3PT_HUMAN,sp|P04406|G3P_HUMAN,tr|E7EUT5|E7EUT5_HUMAN" 3 1047.5383 0.87 30521 14933 2 1047.538361 524.7764 "Glyceraldehyde-3-phosphate dehydrogenase, testis-specific OS=Homo sapiens OX=9606 GN=GAPDHS PE=1 SV=2" 5.8 2772.2 - 7.32E+06 - - - 0.0773 - 1.792 0.38 - 320.8 1 1 0 0.0001 9 0 0 0 2.22E+08 2.55E+08 - - - 3.5353 0.99 221125_WJC_METTL3_EV_vs_WT_F03.14934.14934.2 0.189 18-Aug K.LVESLPQEIK.A "sp|P52815|RM12_HUMAN,tr|B4DLN1|B4DLN1_HUMAN" 2 1154.6547 1.83 30522 14934 2 1154.655895 578.3346 "39S ribosomal protein L12, mitochondrial OS=Homo sapiens OX=9606 GN=MRPL12 PE=1 SV=2" 4.53 2772.2 - 2.30E+06 - - - 1.0436 - 1.392 0.116 - 175.4 1 2 0 0.0012 10 0 0 0 8.57E+07 4.68E+07 - - - 0.8206 0.9991 221125_WJC_METTL3_EV_vs_WT_F03.14935.14935.2 0.00493 20-Oct K.EADLDVATITK.T sp|P57740|NU107_HUMAN 1 1174.6081 0.92 30523 14935 2 1174.607087 588.3113 Nuclear pore complex protein Nup107 OS=Homo sapiens OX=9606 GN=NUP107 PE=1 SV=1 4.03 2772.3 - 2.15E+06 - - - -0.8914 - 2.157 0.204 - 237.4 1 2 0 -0.001 11 0 0 0 4.13E+07 4.50E+07 - - - 2.627 0.9999 221125_WJC_METTL3_EV_vs_WT_F03.14936.14936.3 0.0246 15/40 R.NLPLPPPPPPR.G "sp|P61978|HNRPK_HUMAN,tr|Q5T6W2|Q5T6W2_HUMAN" 2 1193.6921 1.31 30524 14936 3 1193.691947 398.9046 Heterogeneous nuclear ribonucleoprotein K OS=Homo sapiens OX=9606 GN=HNRNPK PE=1 SV=1 9.75 2772.3 - 1.34E+06 - - - -0.1097 - 3.109 0.291 - 385.4 1 2 0 -0.0001 11 0 0 0 2.20E+07 1.68E+07 - - - 5.0067 0.9967 221125_WJC_METTL3_EV_vs_WT_F03.14937.14937.3 0.000727 15/40 K.FAASGGFLHHM.A "sp|Q9BY77|PDIP3_HUMAN,tr|F6VRR5|F6VRR5_HUMAN,tr|F8WCX5|F8WCX5_HUMAN,tr|Q8WUT1|Q8WUT1_HUMAN,tr|F8WEE2|F8WEE2_HUMAN" 5 1173.5389 - 30525 14937 3 1173.539418 392.1869 Polymerase delta-interacting protein 3 OS=Homo sapiens OX=9606 GN=POLDIP3 PE=1 SV=2 6.92 2772.5 - 1.19E+06 - - - 0.3996 - 2.52 0.475 - 173 1 1 0 0.0005 11 0 0 0 - - - - - 6.4613 0.9988 221125_WJC_METTL3_EV_vs_WT_F03.14938.14938.2 0.0515 18-Aug K.EQPWVSVQPR[166.11].K "sp|Q14204|DYHC1_HUMAN,tr|A0A7P0T8N2|A0A7P0T8N2_HUMAN,tr|A0A7P0T9C4|A0A7P0T9C4_HUMAN,tr|A0A7P0TBJ7|A0A7P0TBJ7_HUMAN,tr|A0A804HHY6|A0A804HHY6_HUMAN,tr|A0A7P0T9K2|A0A7P0T9K2_HUMAN,tr|A0A7P0TB64|A0A7P0TB64_HUMAN,tr|A0A2R8Y706|A0A2R8Y706_HUMAN,tr|A0A7P0T916|A0A7P0T916_HUMAN,tr|A0A7P0TB75|A0A7P0TB75_HUMAN,tr|A0A7P0T8W5|A0A7P0T8W5_HUMAN,tr|A0A7P0T9S3|A0A7P0T9S3_HUMAN,tr|A0A7P0TAF3|A0A7P0TAF3_HUMAN,tr|A0A7P0T9F1|A0A7P0T9F1_HUMAN,tr|A0A7P0TAW9|A0A7P0TAW9_HUMAN,tr|A0A2R8YGC7|A0A2R8YGC7_HUMAN,tr|A0A7P0TA13|A0A7P0TA13_HUMAN,tr|A0A7P0T934|A0A7P0T934_HUMAN,tr|A0A7P0TAV5|A0A7P0TAV5_HUMAN,tr|A0A7P0T9Y3|A0A7P0T9Y3_HUMAN,tr|A0A7P0T7V5|A0A7P0T7V5_HUMAN,tr|A0A7P0T9R4|A0A7P0T9R4_HUMAN,tr|A0A2R8Y5T0|A0A2R8Y5T0_HUMAN,tr|A0A7P0T990|A0A7P0T990_HUMAN,tr|A0A7P0T942|A0A7P0T942_HUMAN,tr|A0A2R8YFZ7|A0A2R8YFZ7_HUMAN,tr|A0A7P0T825|A0A7P0T825_HUMAN,tr|A0A2R8Y6H2|A0A2R8Y6H2_HUMAN,tr|A0A7P0TAM4|A0A7P0TAM4_HUMAN" 29 1234.6334 0.63 30526 14938 2 1234.634611 618.324 Cytoplasmic dynein 1 heavy chain 1 OS=Homo sapiens OX=9606 GN=DYNC1H1 PE=1 SV=5 6.1 2772.5 - 936745 - - - 0.9881 - 1.612 0.279 - 222.6 1 2 0 0.0012 10 0 0 0 2.15E+07 3.38E+07 - - - 2.4341 0.8688 221125_WJC_METTL3_EV_vs_WT_F03.14939.14939.2 0.61 14-Jul K.DK[136.11]GFGFIR[166.11].L "sp|Q15233|NONO_HUMAN,tr|A0A7I2V535|A0A7I2V535_HUMAN,tr|A0A7I2V4N2|A0A7I2V4N2_HUMAN,tr|A0A7I2V4K9|A0A7I2V4K9_HUMAN,tr|A0A7I2V464|A0A7I2V464_HUMAN,tr|A0A7P0MRW0|A0A7P0MRW0_HUMAN,tr|H7C367|H7C367_HUMAN,tr|C9IZL7|C9IZL7_HUMAN,tr|A0A7I2YQK8|A0A7I2YQK8_HUMAN,tr|A0A7I2V4J2|A0A7I2V4J2_HUMAN,tr|A0A7I2V5Y7|A0A7I2V5Y7_HUMAN,tr|C9JYS8|C9JYS8_HUMAN" 12 956.5199 0.86 30527 14939 2 956.519836 479.2672 Non-POU domain-containing octamer-binding protein OS=Homo sapiens OX=9606 GN=NONO PE=1 SV=4 8.75 2772.6 - 793142 - - - -0.0366 - 1.403 0.078 - 136.9 3 2 1 0 8 0 0 0 2.04E+07 2.38E+07 - - - 0.4252 0.9999 221125_WJC_METTL3_EV_vs_WT_F03.14942.14942.2 0.00167 13/28 K.IQQLTALGAAQATAK[136.11].A "sp|Q99471|PFD5_HUMAN,tr|H3BMQ1|H3BMQ1_HUMAN,tr|H3BPF6|H3BPF6_HUMAN,tr|F8VNW6|F8VNW6_HUMAN,tr|A0A0D9SFR8|A0A0D9SFR8_HUMAN" 5 1491.85 1.36 30530 14942 2 1491.850557 746.9323 Prefoldin subunit 5 OS=Homo sapiens OX=9606 GN=PFDN5 PE=1 SV=2 8.75 2773.1 - 410790 - - - 0.3452 - 2.367 0.487 - 505.6 1 2 0 0.0005 15 0 0 0 2.85E+06 2.09E+06 - - - 4.7562 0.9997 221125_WJC_METTL3_EV_vs_WT_F03.14943.14943.2 0.000715 13/28 K.IQQLTALGAAQATAK.A "sp|Q99471|PFD5_HUMAN,tr|H3BMQ1|H3BMQ1_HUMAN,tr|H3BPF6|H3BPF6_HUMAN,tr|F8VNW6|F8VNW6_HUMAN,tr|A0A0D9SFR8|A0A0D9SFR8_HUMAN" 5 1483.8358 1.36 30531 14943 2 1483.838727 742.9252 Prefoldin subunit 5 OS=Homo sapiens OX=9606 GN=PFDN5 PE=1 SV=2 8.75 2773.2 - 232541 - - - 1.9443 - 2.641 0.465 - 391.9 1 2 0 0.0029 15 0 0 0 2.85E+06 2.09E+06 - - - 4.8622 0.9997 221125_WJC_METTL3_EV_vs_WT_F03.14946.14946.2 0.000399 16-Sep R.K[136.11]FVADGIFK[136.11].A "sp|P23396|RS3_HUMAN,tr|E9PL09|E9PL09_HUMAN,tr|E9PK82|E9PK82_HUMAN,tr|F2Z2S8|F2Z2S8_HUMAN,tr|H0YCJ7|H0YCJ7_HUMAN,tr|E9PQ96|E9PQ96_HUMAN,tr|E9PJH4|E9PJH4_HUMAN,tr|E9PQX2|E9PQX2_HUMAN,tr|E9PPU1|E9PPU1_HUMAN" 9 1039.6037 3.74 30532 14946 2 1039.605518 520.8091 40S ribosomal protein S3 OS=Homo sapiens OX=9606 GN=RPS3 PE=1 SV=2 8.59 2773.6 - 7.03E+06 - - - 1.7324 - 2.243 0.447 - 246 1 2 0 0.0018 9 0 0 0 4.34E+08 1.16E+08 - - - 4.679 0.9995 221125_WJC_METTL3_EV_vs_WT_F03.14947.14947.3 0.0054 Dec-40 R.EVYALLYSDKK.D "sp|Q9NPF5|DMAP1_HUMAN,tr|Q5TG38|Q5TG38_HUMAN,tr|Q5TG40|Q5TG40_HUMAN,tr|Q5TG37|Q5TG37_HUMAN" 4 1327.7024 1.14 30533 14947 3 1327.702601 443.5747 DNA methyltransferase 1-associated protein 1 OS=Homo sapiens OX=9606 GN=DMAP1 PE=1 SV=1 6.17 2773.6 - 1.92E+06 - - - 0.1755 - 1.806 0.327 - 117.4 1 2 0 0.0002 11 0 0 0 4.64E+07 4.08E+07 - - - 3.8649 0.9994 221125_WJC_METTL3_EV_vs_WT_F03.14948.14948.2 0.00255 18-Oct K.LVESLPQEIK[136.11].A "sp|P52815|RM12_HUMAN,tr|B4DLN1|B4DLN1_HUMAN" 2 1162.6689 1.87 30534 14948 2 1162.669762 582.3417 "39S ribosomal protein L12, mitochondrial OS=Homo sapiens OX=9606 GN=MRPL12 PE=1 SV=2" 4.53 2773.7 - 2.16E+06 - - - 0.75 - 1.616 0.355 - 250.8 1 2 0 0.0009 10 0 0 0 8.53E+07 4.55E+07 - - - 3.0025 0.9997 221125_WJC_METTL3_EV_vs_WT_F03.14949.14949.3 7.50E-07 19/72 R.GLLQDDAHPTLVTYADHSK[136.11].L "sp|Q86U44|MTA70_HUMAN,tr|F5H6D8|F5H6D8_HUMAN,tr|H0YFV6|H0YFV6_HUMAN,tr|B4DTN4|B4DTN4_HUMAN" 4 2088.0367 0.02 30535 14949 3 2088.027437 697.0195 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 5.13 2773.8 - 1.80E+06 - - - -4.452 - 2.695 0.504 - 207.4 1 2 0 -0.0093 19 0 0 0 6.06E+06 2.58E+08 - - - 6.5922 0.9956 221125_WJC_METTL3_EV_vs_WT_F03.14953.14953.2 0.0633 16-Aug K.IGPLGLSPK[136.11].K sp|P30050|RL12_HUMAN 1 888.5524 1.35 30539 14953 2 888.552214 445.2835 60S ribosomal protein L12 OS=Homo sapiens OX=9606 GN=RPL12 PE=1 SV=1 8.75 2774.1 - 733645 - - - -0.2127 - 1.194 0.239 - 103.6 2 2 0 -0.0002 9 0 0 0 2.05E+07 1.52E+07 - - - 1.1847 0.9998 221125_WJC_METTL3_EV_vs_WT_F03.14954.14954.2 2.23E-07 26-Dec R.TPPYADPSLQAPVR[166.11].V "sp|Q04206|TF65_HUMAN,tr|A0A087X0W8|A0A087X0W8_HUMAN,tr|E9PKH5|E9PKH5_HUMAN,tr|Q2TAM5|Q2TAM5_HUMAN" 4 1520.7863 0.16 30540 14954 2 1520.787515 761.4004 Transcription factor p65 OS=Homo sapiens OX=9606 GN=RELA PE=1 SV=2 5.5 2774.3 - 334976 - - - 0.8233 - 1.977 0.527 - 297 1 2 0 0.0013 14 0 0 0 5.34E+06 3.28E+07 - - - 4.6434 0.9998 221125_WJC_METTL3_EV_vs_WT_F03.14960.14960.2 0.0115 20-Oct K.EEEWDPEYTPK.S "sp|Q9NYF8|BCLF1_HUMAN,sp|Q9Y2W1|TR150_HUMAN,tr|A0A3B3ITZ9|A0A3B3ITZ9_HUMAN,tr|H0YF14|H0YF14_HUMAN" 4 1421.5987 3.1 30544 14960 2 1421.598531 711.8066 Bcl-2-associated transcription factor 1 OS=Homo sapiens OX=9606 GN=BCLAF1 PE=1 SV=2 3.91 2774.9 - 1.92E+06 - - - -0.1125 - 2.145 0.44 - 351.9 1 2 0 -0.0002 11 0 0 0 7.02E+08 2.27E+08 - - - 4.3553 0.9999 221125_WJC_METTL3_EV_vs_WT_F03.14962.14962.3 0.000454 Oct-32 K.DYAFVHMER.A "sp|Q9BWF3|RBM4_HUMAN,sp|Q9BQ04|RBM4B_HUMAN,tr|E9PM61|E9PM61_HUMAN,tr|D6R9K7|D6R9K7_HUMAN,tr|J3QRR5|J3QRR5_HUMAN,tr|E9PB51|E9PB51_HUMAN,tr|U3KQD5|U3KQD5_HUMAN,tr|E9PLB0|E9PLB0_HUMAN" 8 1166.5179 1.39 30546 14962 3 1166.517394 389.8466 RNA-binding protein 4 OS=Homo sapiens OX=9606 GN=RBM4 PE=1 SV=1 5.32 2775.2 - 1.01E+06 - - - -0.4158 - 1.801 0.464 - 189.2 1 2 0 -0.0005 9 0 0 0 5.00E+08 3.60E+08 - - - 5.4861 0.9984 221125_WJC_METTL3_EV_vs_WT_F03.14963.14963.2 0.117 14-Jun K.NFSEVFQK.L sp|Q9UQE7|SMC3_HUMAN 1 997.4869 0.87 30547 14963 2 997.486427 499.7507 Structural maintenance of chromosomes protein 3 OS=Homo sapiens OX=9606 GN=SMC3 PE=1 SV=2 6 2775.2 - 1.00E+06 - - - -0.4702 - 1.391 0.266 - 111 1 2 0 -0.0005 8 0 0 0 3.56E+07 4.09E+07 - - - 2.0009 0.9998 221125_WJC_METTL3_EV_vs_WT_F03.14964.14964.2 6.44E-06 13/24 K.TGAELVTC[160.03]GSVLK[136.11].L sp|Q9HCN8|SDF2L_HUMAN 1 1341.7054 1.94 30548 14964 2 1341.702713 671.86 Stromal cell-derived factor 2-like protein 1 OS=Homo sapiens OX=9606 GN=SDF2L1 PE=1 SV=2 5.66 2775.4 - 877193 - - - -1.9669 - 2.958 0.498 - 619.3 1 2 0 -0.0026 13 0 0 0 1.66E+07 8.55E+06 - - - 5.5018 0.7724 221125_WJC_METTL3_EV_vs_WT_F03.14967.14967.2 0.0644 18-Sep K.GDFFPPERPQ.Q "sp|P52272|HNRPM_HUMAN,tr|M0R019|M0R019_HUMAN,tr|M0R0N3|M0R0N3_HUMAN,tr|A0A087X0X3|A0A087X0X3_HUMAN,tr|M0QZM1|M0QZM1_HUMAN,tr|M0R2T0|M0R2T0_HUMAN" 6 1188.5564 43.42 30551 14967 2 1188.560215 595.2855 Heterogeneous nuclear ribonucleoprotein M OS=Homo sapiens OX=9606 GN=HNRNPM PE=1 SV=3 4.37 2775.8 - 435916 - - - 3.2325 - 1.311 0.361 - 173.6 1 1 0 0.0038 10 0 0 0 1.08E+07 2.50E+05 - - - 2.462 0.9999 221125_WJC_METTL3_EV_vs_WT_F03.14970.14970.2 2.64E-05 14/20 R.TAAENDFVTLK.K sp|P35908|K22E_HUMAN 1 1207.6085 18.69 30553 14970 2 1207.609761 604.8115 "Keratin, type II cytoskeletal 2 epidermal OS=Homo sapiens OX=9606 GN=KRT2 PE=1 SV=2" 4.37 2776.1 - 1.02E+08 - - - 1.0707 - 2.755 0.464 - 640.2 1 2 0 0.0013 11 0 0 0 3.47E+09 1.86E+08 - - - 5.2092 0.9999 221125_WJC_METTL3_EV_vs_WT_F03.14971.14971.2 4.31E-06 20-Dec K.EEEWDPEYTPK[136.11].S "sp|Q9NYF8|BCLF1_HUMAN,sp|Q9Y2W1|TR150_HUMAN,tr|A0A3B3ITZ9|A0A3B3ITZ9_HUMAN,tr|H0YF14|H0YF14_HUMAN" 4 1429.6129 3.1 30554 14971 2 1429.613058 715.8137 Bcl-2-associated transcription factor 1 OS=Homo sapiens OX=9606 GN=BCLAF1 PE=1 SV=2 3.91 2776.2 - 1.94E+06 - - - 0.1168 - 2.159 0.588 - 579.5 1 2 0 0.0002 11 0 0 0 7.02E+08 2.27E+08 - - - 5.466 0.9678 221125_WJC_METTL3_EV_vs_WT_F03.14973.14973.2 0.0509 18-Sep Q.SLSMPASLGR.M "sp|P43243|MATR3_HUMAN,tr|A0A1B0GX04|A0A1B0GX04_HUMAN,tr|D6RBS2|D6RBS2_HUMAN,tr|A8MXP9|A8MXP9_HUMAN,tr|D6R991|D6R991_HUMAN,tr|D6REK4|D6REK4_HUMAN,tr|D6R9F3|D6R9F3_HUMAN,tr|A0A0R4J2E8|A0A0R4J2E8_HUMAN,tr|D6RB45|D6RB45_HUMAN,tr|D6RCM3|D6RCM3_HUMAN,tr|D6R8Z5|D6R8Z5_HUMAN,tr|D6REM6|D6REM6_HUMAN" 12 1017.5277 1.3 30556 14973 2 1017.526967 509.7711 Matrin-3 OS=Homo sapiens OX=9606 GN=MATR3 PE=1 SV=2 9.47 2776.4 - 1.67E+06 - - - -0.7351 - 1.609 0.357 - 275.8 1 1 0 -0.0007 10 0 0 0 2.10E+08 1.61E+08 - - - 3.0051 1 221125_WJC_METTL3_EV_vs_WT_F03.14975.14975.3 1.87E-13 21/96 K.LVQDVANNTNEEAGDGTTTATVLAR[166.11].S "sp|P10809|CH60_HUMAN,tr|C9JL25|C9JL25_HUMAN,tr|A0A7I2V2X6|A0A7I2V2X6_HUMAN,tr|A0A7I2YQK6|A0A7I2YQK6_HUMAN,tr|A0A7I2V599|A0A7I2V599_HUMAN,tr|E7EXB4|E7EXB4_HUMAN,tr|A0A7I2YQ71|A0A7I2YQ71_HUMAN,tr|E7ESH4|E7ESH4_HUMAN,tr|A0A7I2V5M1|A0A7I2V5M1_HUMAN,tr|A0A7I2V5K3|A0A7I2V5K3_HUMAN,tr|A0A7I2V369|A0A7I2V369_HUMAN" 11 2569.2495 1.37 30558 14975 3 2569.252528 857.4238 "60 kDa heat shock protein, mitochondrial OS=Homo sapiens OX=9606 GN=HSPD1 PE=1 SV=2" 3.92 2776.6 - 724817 - - - 1.1696 - 4.038 0.66 - 652 1 2 0 0.003 25 0 0 0 1.03E+07 7.56E+06 - - - 9.1086 0.9997 221125_WJC_METTL3_EV_vs_WT_F03.14976.14976.3 0.00175 14/44 K.LSDFGLC[160.03]TGLKK.A "sp|Q9Y2H1|ST38L_HUMAN,sp|Q15208|STK38_HUMAN,tr|F5H277|F5H277_HUMAN,tr|H0YGN4|H0YGN4_HUMAN" 4 1337.7013 2.74 30559 14976 3 1337.702847 446.9077 Serine\threonine-protein kinase 38-like OS=Homo sapiens OX=9606 GN=STK38L PE=1 SV=3 8.2 2776.7 - 657417 - - - 1.1393 - 2.443 0.306 - 217.8 1 2 0 0.0015 12 0 0 0 6.45E+07 2.35E+07 - - - 4.4271 0.999 221125_WJC_METTL3_EV_vs_WT_F03.14982.14982.2 0.146 13/18 R.R[166.11]VLQALEGLK[136.11].M "sp|P39019|RS19_HUMAN,tr|A0A075B6E2|A0A075B6E2_HUMAN" 2 1143.7095 1.09 30563 14982 2 1143.70887 572.862 40S ribosomal protein S19 OS=Homo sapiens OX=9606 GN=RPS19 PE=1 SV=2 8.75 2777.4 - 1.66E+07 - - - -0.5185 - 2.287 0.145 - 574.9 1 2 0 -0.0006 10 0 0 0 1.81E+09 1.66E+09 - - - 2.4209 0.9981 221125_WJC_METTL3_EV_vs_WT_F03.14984.14984.2 0.0374 14-Jul K.NFSEVFQK[136.11].L sp|Q9UQE7|SMC3_HUMAN 1 1005.5011 0.87 30565 14984 2 1005.500532 503.7578 Structural maintenance of chromosomes protein 3 OS=Homo sapiens OX=9606 GN=SMC3 PE=1 SV=2 6 2777.5 - 3.30E+06 - - - -0.5609 - 1.312 0.269 - 182.4 1 2 0 -0.0006 8 0 0 0 3.56E+07 4.09E+07 - - - 1.8466 0.9998 221125_WJC_METTL3_EV_vs_WT_F03.14985.14985.2 0.000849 18-Oct K.STIGVEFATR[166.11].S "sp|Q15907|RB11B_HUMAN,sp|P62491|RB11A_HUMAN,tr|H3BMH2|H3BMH2_HUMAN,tr|H3BSC1|H3BSC1_HUMAN" 4 1089.5694 0.91 30566 14985 2 1089.569553 545.792 Ras-related protein Rab-11B OS=Homo sapiens OX=9606 GN=RAB11B PE=1 SV=4 5.72 2777.6 - 3.22E+06 - - - 0.1459 - 2.214 0.361 - 341.4 1 2 0 0.0002 10 0 0 0 1.46E+08 1.60E+08 - - - 3.9258 0.9997 221125_WJC_METTL3_EV_vs_WT_F03.14986.14986.2 0.00138 18-Sep K.STIGVEFATR.S "sp|Q15907|RB11B_HUMAN,sp|P62491|RB11A_HUMAN,tr|H3BMH2|H3BMH2_HUMAN,tr|H3BSC1|H3BSC1_HUMAN" 4 1079.5611 0.91 30567 14986 2 1079.561512 540.7878 Ras-related protein Rab-11B OS=Homo sapiens OX=9606 GN=RAB11B PE=1 SV=4 5.72 2777.6 - 2.99E+06 - - - 0.3594 - 1.754 0.398 - 196.3 1 2 0 0.0004 10 0 0 0 1.46E+08 1.61E+08 - - - 3.5489 0.9936 221125_WJC_METTL3_EV_vs_WT_F03.14988.14988.2 0.000552 18-Oct K.EDNIGNQLLR[166.11].K sp|O15226|NKRF_HUMAN 1 1180.6076 0.67 30569 14988 2 1180.60645 591.3111 NF-kappa-B-repressing factor OS=Homo sapiens OX=9606 GN=NKRF PE=1 SV=2 4.37 2777.8 - 1.65E+06 - - - -0.9487 - 1.75 0.059 - 233.3 1 2 0 -0.0011 10 0 0 0 3.49E+07 5.19E+07 - - - 1.0385 0.9891 221125_WJC_METTL3_EV_vs_WT_F03.14989.14989.2 0.232 24-Dec K.QILDPAASVTGSR[166.11].R sp|P46013|KI67_HUMAN 1 1323.7022 1.53 30570 14989 2 1323.702 662.8584 Proliferation marker protein Ki-67 OS=Homo sapiens OX=9606 GN=MKI67 PE=1 SV=2 5.84 2777.9 - 1.58E+06 - - - -0.1503 - 1.647 0.032 - 401.9 1 2 0 -0.0002 13 0 0 0 2.72E+07 1.77E+07 - - - 0.5579 0.9985 221125_WJC_METTL3_EV_vs_WT_F03.14992.14992.2 0.0109 16-Jul R.ANTFVAELK.G "sp|P40926|MDHM_HUMAN,tr|G3XAL0|G3XAL0_HUMAN" 2 991.5338 0.73 30573 14992 2 991.5356 496.7742 "Malate dehydrogenase, mitochondrial OS=Homo sapiens OX=9606 GN=MDH2 PE=1 SV=3" 6.05 2778.3 - 1.23E+06 - - - 1.769 - 1.626 0.3 - 204.3 1 2 0 0.0018 9 0 0 0 1.46E+07 2.00E+07 - - - 2.6626 0.9982 221125_WJC_METTL3_EV_vs_WT_F03.14993.14993.2 0.0235 18-Nov R.SSLLIEQPVK.K "sp|Q8NDX5|PHC3_HUMAN,tr|E7EX82|E7EX82_HUMAN" 2 1112.6441 1.66 30574 14993 2 1112.646183 557.3293 Polyhomeotic-like protein 3 OS=Homo sapiens OX=9606 GN=PHC3 PE=1 SV=1 5.72 2778.3 - 1.15E+06 - - - 1.8496 - 1.881 0.231 - 300.8 1 2 0 0.0021 10 0 0 0 1.44E+07 8.68E+06 - - - 2.5101 1 221125_WJC_METTL3_EV_vs_WT_F03.14994.14994.3 2.04E-15 20/96 K.LVQDVANNTNEEAGDGTTTATVLAR.S "sp|P10809|CH60_HUMAN,tr|C9JL25|C9JL25_HUMAN,tr|A0A7I2V2X6|A0A7I2V2X6_HUMAN,tr|A0A7I2YQK6|A0A7I2YQK6_HUMAN,tr|A0A7I2V599|A0A7I2V599_HUMAN,tr|E7EXB4|E7EXB4_HUMAN,tr|A0A7I2YQ71|A0A7I2YQ71_HUMAN,tr|E7ESH4|E7ESH4_HUMAN,tr|A0A7I2V5M1|A0A7I2V5M1_HUMAN,tr|A0A7I2V5K3|A0A7I2V5K3_HUMAN,tr|A0A7I2V369|A0A7I2V369_HUMAN" 11 2559.2413 1.37 30575 14994 3 2559.239191 854.0877 "60 kDa heat shock protein, mitochondrial OS=Homo sapiens OX=9606 GN=HSPD1 PE=1 SV=2" 3.92 2778.5 - 961357 - - - -0.8057 - 3.933 0.735 - 541.9 1 2 0 -0.0021 25 0 0 0 1.03E+07 7.56E+06 - - - 9.8845 0.9996 221125_WJC_METTL3_EV_vs_WT_F03.14996.14996.2 0.00173 13/26 K.NVVLPTETEVAPAK[136.11].D "sp|P27816|MAP4_HUMAN,tr|E7EVA0|E7EVA0_HUMAN,tr|A0A804HKE7|A0A804HKE7_HUMAN" 3 1474.8123 0.67 30577 14996 2 1474.814942 738.4134 Microtubule-associated protein 4 OS=Homo sapiens OX=9606 GN=MAP4 PE=1 SV=3 4.53 2778.7 - 526381 - - - 1.8185 - 2.334 0.383 - 413.8 1 2 0 0.0027 14 0 0 0 9.12E+06 1.36E+07 - - - 3.996 0.9994 221125_WJC_METTL3_EV_vs_WT_F03.14998.14998.2 0.00442 13/26 K.NVVLPTETEVAPAK.D "sp|P27816|MAP4_HUMAN,tr|E7EVA0|E7EVA0_HUMAN,tr|A0A804HKE7|A0A804HKE7_HUMAN" 3 1466.7981 0.67 30579 14998 2 1466.795568 734.4063 Microtubule-associated protein 4 OS=Homo sapiens OX=9606 GN=MAP4 PE=1 SV=3 4.53 2779 - 322344 - - - -1.6989 - 2.275 0.319 - 452 1 2 0 -0.0025 14 0 0 0 9.12E+06 1.36E+07 - - - 3.4591 0.9998 221125_WJC_METTL3_EV_vs_WT_F03.15001.15001.3 0.0155 14/48 K.ILDAVVAQEPLHR.G "sp|Q15029|U5S1_HUMAN,tr|K7EJ74|K7EJ74_HUMAN,tr|K7EP67|K7EP67_HUMAN" 3 1459.8147 1.66 30580 15001 3 1459.813107 487.6122 116 kDa U5 small nuclear ribonucleoprotein component OS=Homo sapiens OX=9606 GN=EFTUD2 PE=1 SV=1 5.32 2779.3 - 3.78E+06 - - - -1.1001 - 2.315 0.325 - 366.8 1 2 0 -0.0016 13 0 0 0 3.01E+08 1.81E+08 - - - 4.4389 0.9999 221125_WJC_METTL3_EV_vs_WT_F03.15002.15002.2 1.46E-07 16-Oct K.DYAFVHMER.A "sp|Q9BWF3|RBM4_HUMAN,sp|Q9BQ04|RBM4B_HUMAN,tr|E9PM61|E9PM61_HUMAN,tr|D6R9K7|D6R9K7_HUMAN,tr|J3QRR5|J3QRR5_HUMAN,tr|E9PB51|E9PB51_HUMAN,tr|U3KQD5|U3KQD5_HUMAN,tr|E9PLB0|E9PLB0_HUMAN" 8 1166.5179 1.37 30581 15002 2 1166.517275 584.2662 RNA-binding protein 4 OS=Homo sapiens OX=9606 GN=RBM4 PE=1 SV=1 5.32 2779.4 - 3.67E+06 - - - -0.5178 - 2.047 0.618 - 480.1 1 2 0 -0.0006 9 0 0 0 1.02E+08 7.41E+07 - - - 5.6779 0.9998 221125_WJC_METTL3_EV_vs_WT_F03.15003.15003.2 0.0136 14/18 R.RVLQALEGLK.M "sp|P39019|RS19_HUMAN,tr|A0A075B6E2|A0A075B6E2_HUMAN" 2 1125.687 1.09 30582 15003 2 1125.686691 563.8508 40S ribosomal protein S19 OS=Homo sapiens OX=9606 GN=RPS19 PE=1 SV=2 8.75 2779.4 - 2.86E+07 - - - -0.2683 - 2.443 0.354 - 578.1 1 2 0 -0.0003 10 0 0 0 1.82E+09 1.66E+09 - - - 4.1488 0.9999 221125_WJC_METTL3_EV_vs_WT_F03.15007.15007.3 0.000384 17/48 K.ILDAVVAQEPLHR[166.11].G "sp|Q15029|U5S1_HUMAN,tr|K7EJ74|K7EJ74_HUMAN,tr|K7EP67|K7EP67_HUMAN" 3 1469.823 1.67 30586 15007 3 1469.822606 490.9483 116 kDa U5 small nuclear ribonucleoprotein component OS=Homo sapiens OX=9606 GN=EFTUD2 PE=1 SV=1 5.32 2779.7 - 2.07E+06 - - - -0.2565 - 3.062 0.372 - 430.6 1 2 0 -0.0004 13 0 0 0 3.02E+08 1.81E+08 - - - 5.7214 0.9999 221125_WJC_METTL3_EV_vs_WT_F03.15008.15008.2 1.10E-06 22-Nov R.EYPSEQIIVTEK[136.11].T sp|Q9BW61|DDA1_HUMAN 1 1442.7384 1.61 30587 15008 2 1442.73733 722.3765 DET1- and DDB1-associated protein 1 OS=Homo sapiens OX=9606 GN=DDA1 PE=1 SV=1 4.25 2779.9 - 1.49E+06 - - - -0.7597 - 2.119 0.531 - 420.3 1 2 0 -0.0011 12 0 0 0 7.36E+07 4.57E+07 - - - 4.9385 0.9989 221125_WJC_METTL3_EV_vs_WT_F03.15009.15009.2 0.0109 18-Oct K.GIQEIADSVK.A "sp|O00330|ODPX_HUMAN,tr|H0YD97|H0YD97_HUMAN" 2 1058.5608 0.6 30588 15009 2 1058.559544 530.2877 "Pyruvate dehydrogenase protein X component, mitochondrial OS=Homo sapiens OX=9606 GN=PDHX PE=1 SV=3" 4.37 2780 - 1.24E+06 - - - -1.1761 - 1.731 0.265 - 300.5 1 2 0 -0.0012 10 0 0 0 2.88E+07 4.79E+07 - - - 2.5295 0.9995 221125_WJC_METTL3_EV_vs_WT_F03.15010.15010.2 0.000213 13/24 R.GAGGGGLWGPGVR[166.11].A sp|Q86SX6|GLRX5_HUMAN 1 1149.5919 1.93 30589 15010 2 1149.594985 575.8032 "Glutaredoxin-related protein 5, mitochondrial OS=Homo sapiens OX=9606 GN=GLRX5 PE=1 SV=2" 9.75 2780.1 - 1.08E+06 - - - 2.7175 - 2.69 0.446 - 508 1 2 0 0.0031 13 0 0 0 2.67E+07 1.38E+07 - - - 4.8739 0.9999 221125_WJC_METTL3_EV_vs_WT_F03.15014.15014.2 2.08E-06 16-Oct K.DYAFVHMER[166.11].A "sp|Q9BWF3|RBM4_HUMAN,sp|Q9BQ04|RBM4B_HUMAN,tr|E9PM61|E9PM61_HUMAN,tr|D6R9K7|D6R9K7_HUMAN,tr|J3QRR5|J3QRR5_HUMAN,tr|E9PB51|E9PB51_HUMAN,tr|U3KQD5|U3KQD5_HUMAN,tr|E9PLB0|E9PLB0_HUMAN" 8 1176.5261 1.37 30591 15014 2 1176.525322 589.2704 RNA-binding protein 4 OS=Homo sapiens OX=9606 GN=RBM4 PE=1 SV=1 5.32 2780.6 - 4.18E+06 - - - -0.7029 - 2.036 0.547 - 460.1 1 2 0 -0.0008 9 0 0 0 1.02E+08 7.41E+07 - - - 5.1378 0.9571 221125_WJC_METTL3_EV_vs_WT_F03.15016.15016.2 0.00708 12-Jul Y.AFVHMER[166.11].A "sp|Q9BWF3|RBM4_HUMAN,sp|Q9BQ04|RBM4B_HUMAN,tr|E9PM61|E9PM61_HUMAN,tr|D6R9K7|D6R9K7_HUMAN,tr|J3QRR5|J3QRR5_HUMAN,tr|E9PB51|E9PB51_HUMAN,tr|U3KQD5|U3KQD5_HUMAN,tr|E9PLB0|E9PLB0_HUMAN" 8 898.4359 1.28 30593 15016 2 898.435341 450.2252 RNA-binding protein 4 OS=Homo sapiens OX=9606 GN=RBM4 PE=1 SV=1 6.79 2780.8 - 3.66E+06 - - - -0.5966 - 1.424 0.341 - 292.6 1 1 0 -0.0005 7 0 0 0 6.63E+07 5.19E+07 - - - 2.6794 0.9999 221125_WJC_METTL3_EV_vs_WT_F03.15017.15017.2 7.99E-05 18-Dec R.TIAQDYGVLK.A "sp|Q06830|PRDX1_HUMAN,tr|A0A0A0MSI0|A0A0A0MSI0_HUMAN" 2 1106.5972 0.66 30594 15017 2 1106.597365 554.3059 Peroxiredoxin-1 OS=Homo sapiens OX=9606 GN=PRDX1 PE=1 SV=1 5.5 2780.9 - 2.81E+06 - - - 0.1717 - 2.093 0.47 - 320.6 1 2 0 0.0002 10 0 0 0 9.85E+07 1.50E+08 - - - 4.574 0.9993 221125_WJC_METTL3_EV_vs_WT_F03.15020.15020.2 0.141 18-Oct K.GIQEIADSVK[136.11].A "sp|O00330|ODPX_HUMAN,tr|H0YD97|H0YD97_HUMAN" 2 1066.575 0.6 30597 15020 2 1066.574109 534.2948 "Pyruvate dehydrogenase protein X component, mitochondrial OS=Homo sapiens OX=9606 GN=PDHX PE=1 SV=3" 4.37 2781.2 - 1.82E+06 - - - -0.8251 - 1.878 0.276 - 296.5 1 2 0 -0.0009 10 0 0 0 2.91E+07 4.84E+07 - - - 2.8384 1 221125_WJC_METTL3_EV_vs_WT_F03.15022.15022.2 9.60E-07 13/20 K.GYAFVQYSNER[166.11].H "sp|Q9UKM9|RALY_HUMAN,tr|Q5QPM2|Q5QPM2_HUMAN,tr|Q5QPM1|Q5QPM1_HUMAN,tr|Q5QPL9|Q5QPL9_HUMAN" 4 1342.6181 1.41 30599 15022 2 1342.61635 672.3163 RNA-binding protein Raly OS=Homo sapiens OX=9606 GN=RALY PE=1 SV=1 6 2781.5 - 1.22E+06 - - - -1.3295 - 2.597 0.59 - 862 1 2 0 -0.0018 11 0 0 0 6.51E+07 4.61E+07 - - - 5.9799 1 221125_WJC_METTL3_EV_vs_WT_F03.15025.15025.3 0.0004 Dec-40 K.SGIC[160.03]SLHPLLR.G "sp|Q9H583|HEAT1_HUMAN,tr|Q5T3Q7|Q5T3Q7_HUMAN" 2 1251.6758 0.83 30602 15025 3 1251.674785 418.2325 HEAT repeat-containing protein 1 OS=Homo sapiens OX=9606 GN=HEATR1 PE=1 SV=3 7.99 2781.9 - 394912 - - - -0.7925 - 2.339 0.448 - 199.5 1 2 0 -0.001 11 0 0 0 6.27E+06 7.55E+06 - - - 5.9484 0.9998 221125_WJC_METTL3_EV_vs_WT_F03.15028.15028.2 0.000206 14-Sep K.QFAFVHMR.E "sp|Q96PK6|RBM14_HUMAN,tr|B8ZZ74|B8ZZ74_HUMAN,tr|F8WDX3|F8WDX3_HUMAN,tr|A0A0A0MSL8|A0A0A0MSL8_HUMAN,tr|A0A0A6YYI9|A0A0A6YYI9_HUMAN" 5 1034.512 0.12 30603 15028 2 1034.512274 518.2633 RNA-binding protein 14 OS=Homo sapiens OX=9606 GN=RBM14 PE=1 SV=2 9.76 2782.2 - 5.27E+06 - - - 0.26 - 1.838 0.49 - 410 1 2 0 0.0003 8 0 0 0 1.04E+08 8.61E+08 - - - 4.4958 1 221125_WJC_METTL3_EV_vs_WT_F03.15031.15031.2 1.15E-07 20-Dec K.GYAFVQYSNER.H "sp|Q9UKM9|RALY_HUMAN,tr|Q5QPM2|Q5QPM2_HUMAN,tr|Q5QPM1|Q5QPM1_HUMAN,tr|Q5QPL9|Q5QPL9_HUMAN" 4 1332.6099 1.4 30606 15031 2 1332.608895 667.3122 RNA-binding protein Raly OS=Homo sapiens OX=9606 GN=RALY PE=1 SV=1 6 2782.4 - 2.45E+06 - - - -0.7279 - 2.589 0.63 - 596.7 1 2 0 -0.001 11 0 0 0 6.55E+07 4.68E+07 - - - 6.2673 1 221125_WJC_METTL3_EV_vs_WT_F03.15034.15034.2 1.89E-05 16/24 K.ILDAVVAQEPLHR.G "sp|Q15029|U5S1_HUMAN,tr|K7EJ74|K7EJ74_HUMAN,tr|K7EP67|K7EP67_HUMAN" 3 1459.8147 2.21 30609 15034 2 1459.813319 730.9146 116 kDa U5 small nuclear ribonucleoprotein component OS=Homo sapiens OX=9606 GN=EFTUD2 PE=1 SV=1 5.32 2782.8 - 1.22E+06 - - - -0.9549 - 3.042 0.608 - 1103.7 1 2 0 -0.0014 13 0 0 0 3.17E+07 1.43E+07 - - - 6.3866 1 221125_WJC_METTL3_EV_vs_WT_F03.15035.15035.2 2.02E-05 14/30 K.VLEQPVVVQSVGTDGR.V "sp|Q9BZE1|RM37_HUMAN,tr|S4R369|S4R369_HUMAN,tr|H0Y4J2|H0Y4J2_HUMAN,tr|A6NHR2|A6NHR2_HUMAN" 4 1681.8999 0.97 30610 15035 2 1681.898334 841.9572 "39S ribosomal protein L37, mitochondrial OS=Homo sapiens OX=9606 GN=MRPL37 PE=1 SV=2" 4.37 2782.9 - 723548 - - - -0.9305 - 3.035 0.659 - 446.6 1 2 0 -0.0016 16 0 0 0 9.84E+06 1.02E+07 - - - 6.6374 1 221125_WJC_METTL3_EV_vs_WT_F03.15036.15036.2 7.52E-08 13/30 K.VLEQPVVVQSVGTDGR[166.11].V "sp|Q9BZE1|RM37_HUMAN,tr|S4R369|S4R369_HUMAN,tr|H0Y4J2|H0Y4J2_HUMAN,tr|A6NHR2|A6NHR2_HUMAN" 4 1691.9082 0.97 30611 15036 2 1691.907947 846.9614 "39S ribosomal protein L37, mitochondrial OS=Homo sapiens OX=9606 GN=MRPL37 PE=1 SV=2" 4.37 2783 - 716977 - - - -0.1312 - 2.689 0.638 - 363.4 1 2 0 -0.0002 16 0 0 0 9.84E+06 1.02E+07 - - - 6.1851 0.9998 221125_WJC_METTL3_EV_vs_WT_F03.15037.15037.2 0.0174 14/26 R.TVLVNADGEEVAMR[166.11].T sp|Q03252|LMNB2_HUMAN 1 1512.7482 1.12 30612 15037 2 1512.750117 757.3814 Lamin-B2 OS=Homo sapiens OX=9606 GN=LMNB2 PE=1 SV=4 4.14 2783.2 - 485518 - - - 1.2917 - 2.791 0.485 - 634.7 1 2 0 0.002 14 0 0 0 4.00E+07 3.58E+07 - - - 5.1983 1 221125_WJC_METTL3_EV_vs_WT_F03.15040.15040.4 0.000249 10/108 R.GLLQDDAHPTLVTYADHSK[136.11].L "sp|Q86U44|MTA70_HUMAN,tr|F5H6D8|F5H6D8_HUMAN,tr|H0YFV6|H0YFV6_HUMAN,tr|B4DTN4|B4DTN4_HUMAN" 4 2088.0367 0.02 30613 15040 4 2088.033963 523.0165 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 5.13 2783.6 - 3.91E+07 - - - -1.3266 - 2.356 0.501 - 97.4 1 2 0 -0.0028 19 0 0 0 1.55E+07 6.23E+08 - - - 3.8758 0.9999 221125_WJC_METTL3_EV_vs_WT_F03.15041.15041.2 3.61E-07 13/20 R.QSVEADINGLR.R "sp|P13645|K1C10_HUMAN,sp|Q2M2I5|K1C24_HUMAN,sp|Q7Z3Y8|K1C27_HUMAN,sp|P13646|K1C13_HUMAN,tr|A0A1B0GVI3|A0A1B0GVI3_HUMAN,tr|K7EMD9|K7EMD9_HUMAN,tr|K7ERE3|K7ERE3_HUMAN" 7 1200.6099 2.36 30614 15041 2 1200.609461 601.3122 "Keratin, type I cytoskeletal 10 OS=Homo sapiens OX=9606 GN=KRT10 PE=1 SV=6" 4.37 2783.6 - 8.88E+06 - - - -0.3365 - 2.618 0.46 - 922.3 1 2 0 -0.0004 11 0 0 0 8.90E+08 3.78E+08 - - - 5.042 0.9997 221125_WJC_METTL3_EV_vs_WT_F03.15042.15042.2 2.14E-05 18-Nov K.DVNAAIATIK[136.11].T "sp|Q6PEY2|TBA3E_HUMAN,sp|P0DPH7|TBA3C_HUMAN,sp|Q71U36|TBA1A_HUMAN,sp|P0DPH8|TBA3D_HUMAN,sp|P68363|TBA1B_HUMAN,sp|Q9BQE3|TBA1C_HUMAN,tr|A0A1W2PQM2|A0A1W2PQM2_HUMAN,tr|F5H5D3|F5H5D3_HUMAN" 8 1022.5852 0.55 30615 15042 2 1022.584305 512.2999 Tubulin alpha-3E chain OS=Homo sapiens OX=9606 GN=TUBA3E PE=1 SV=2 5.84 2783.6 - 5.12E+06 - - - -0.8361 - 2.08 0.343 - 329.2 1 2 0 -0.0009 10 0 0 0 7.70E+08 1.40E+09 - - - 3.6184 0.9996 221125_WJC_METTL3_EV_vs_WT_F03.15044.15044.2 0.0414 18-Nov R.LTQFLEEEGR[166.11].T sp|Q9H0W5|CCDC8_HUMAN 1 1230.612 1.1 30617 15044 2 1230.613072 616.3133 Coiled-coil domain-containing protein 8 OS=Homo sapiens OX=9606 GN=CCDC8 PE=1 SV=2 4.25 2783.8 - 1.73E+06 - - - 0.8817 - 2.545 0.242 - 512.3 1 2 0 0.0011 10 0 0 0 1.08E+08 9.80E+07 - - - 3.4355 0.9999 221125_WJC_METTL3_EV_vs_WT_F03.15046.15046.2 1.34E-05 26-Nov R.LESEGSPETLTNLR.K "sp|Q9P035|HACD3_HUMAN,tr|H3BPZ1|H3BPZ1_HUMAN,tr|H3BS72|H3BS72_HUMAN,tr|H3BMZ1|H3BMZ1_HUMAN,tr|H3BRL8|H3BRL8_HUMAN" 5 1544.7682 1.14 30619 15046 2 1544.767827 773.3914 Very-long-chain (3R)-3-hydroxyacyl-CoA dehydratase 3 OS=Homo sapiens OX=9606 GN=HACD3 PE=1 SV=2 4.25 2784.1 - 1.37E+06 - - - -0.2518 - 2.569 0.541 - 267.5 1 2 0 -0.0004 14 0 0 0 1.87E+07 1.64E+07 - - - 5.4044 0.9995 221125_WJC_METTL3_EV_vs_WT_F03.15047.15047.2 6.76E-06 15/26 R.TVLVNADGEEVAMR.T sp|Q03252|LMNB2_HUMAN 1 1502.7399 1.11 30620 15047 2 1502.744842 752.3772 Lamin-B2 OS=Homo sapiens OX=9606 GN=LMNB2 PE=1 SV=4 4.14 2784.2 - 1.11E+06 - - - 3.2933 - 2.759 0.559 - 764.4 1 2 0 0.0049 14 0 0 0 3.97E+07 3.58E+07 - - - 5.715 0.9692 221125_WJC_METTL3_EV_vs_WT_F03.15048.15048.2 0.00012 12-Jul Q.FAFVHMR[166.11].E "sp|Q96PK6|RBM14_HUMAN,tr|B8ZZ74|B8ZZ74_HUMAN,tr|F8WDX3|F8WDX3_HUMAN,tr|A0A0A0MSL8|A0A0A0MSL8_HUMAN,tr|A0A0A6YYI9|A0A0A6YYI9_HUMAN" 5 916.4617 2.72 30621 15048 2 916.46011 459.2381 RNA-binding protein 14 OS=Homo sapiens OX=9606 GN=RBM14 PE=1 SV=2 9.76 2784.3 - 683631 - - - -1.7328 - 1.46 0.455 - 176.4 1 1 0 -0.0016 7 0 0 0 3.43E+07 1.26E+07 - - - 3.6002 0.9896 221125_WJC_METTL3_EV_vs_WT_F03.15051.15051.3 0.0113 Nov-40 R.QSVEADINGLR.R "sp|P13645|K1C10_HUMAN,sp|Q2M2I5|K1C24_HUMAN,sp|Q7Z3Y8|K1C27_HUMAN,sp|P13646|K1C13_HUMAN,tr|A0A1B0GVI3|A0A1B0GVI3_HUMAN,tr|K7EMD9|K7EMD9_HUMAN,tr|K7ERE3|K7ERE3_HUMAN" 7 1200.6099 4.69 30622 15051 3 1200.607564 401.2106 "Keratin, type I cytoskeletal 10 OS=Homo sapiens OX=9606 GN=KRT10 PE=1 SV=6" 4.37 2784.7 - 1.01E+06 - - - -1.9165 - 1.59 0.202 - 129 1 2 0 -0.0023 11 0 0 0 4.70E+07 1.00E+07 - - - 2.1089 0.9998 221125_WJC_METTL3_EV_vs_WT_F03.15052.15052.2 0.000357 14/24 K.ILDAVVAQEPLHR[166.11].G "sp|Q15029|U5S1_HUMAN,tr|K7EJ74|K7EJ74_HUMAN,tr|K7EP67|K7EP67_HUMAN" 3 1469.823 2.21 30623 15052 2 1469.820635 735.9188 116 kDa U5 small nuclear ribonucleoprotein component OS=Homo sapiens OX=9606 GN=EFTUD2 PE=1 SV=1 5.32 2784.9 - 1.13E+06 - - - -1.5975 - 2.628 0.437 - 517.4 1 2 0 -0.0023 13 0 0 0 3.17E+07 1.43E+07 - - - 4.7478 0.9996 221125_WJC_METTL3_EV_vs_WT_F03.15055.15055.2 0.0226 20-Sep K.C[160.03]DPAGYYC[160.03]GFK.A "sp|P60900|PSA6_HUMAN,tr|G3V5Z7|G3V5Z7_HUMAN,tr|G3V295|G3V295_HUMAN" 3 1336.5216 1.01 30626 15055 2 1336.522604 669.2681 Proteasome subunit alpha type-6 OS=Homo sapiens OX=9606 GN=PSMA6 PE=1 SV=1 5.82 2785.2 - 1.41E+06 - - - 0.7183 - 1.363 0.468 - 190.9 1 2 0 0.001 11 0 0 0 9.31E+06 9.18E+06 - - - 3.3351 0.9582 221125_WJC_METTL3_EV_vs_WT_F03.15058.15058.2 0.0214 12-Jun Y.AFVHMER.A "sp|Q9BWF3|RBM4_HUMAN,sp|Q9BQ04|RBM4B_HUMAN,tr|E9PM61|E9PM61_HUMAN,tr|D6R9K7|D6R9K7_HUMAN,tr|J3QRR5|J3QRR5_HUMAN,tr|E9PB51|E9PB51_HUMAN,tr|U3KQD5|U3KQD5_HUMAN,tr|E9PLB0|E9PLB0_HUMAN" 8 888.4276 1.28 30627 15058 2 888.427312 445.2211 RNA-binding protein 4 OS=Homo sapiens OX=9606 GN=RBM4 PE=1 SV=1 6.79 2785.6 - 3.09E+06 - - - -0.332 - 1.192 0.415 - 231.5 1 1 0 -0.0003 7 0 0 0 6.63E+07 5.19E+07 - - - 2.6626 0.9999 221125_WJC_METTL3_EV_vs_WT_F03.15059.15059.2 1.17E-05 14/26 R.LESEGSPETLTNLR[166.11].K "sp|Q9P035|HACD3_HUMAN,tr|H3BPZ1|H3BPZ1_HUMAN,tr|H3BS72|H3BS72_HUMAN,tr|H3BMZ1|H3BMZ1_HUMAN,tr|H3BRL8|H3BRL8_HUMAN" 5 1554.7765 1.14 30628 15059 2 1554.776337 778.3955 Very-long-chain (3R)-3-hydroxyacyl-CoA dehydratase 3 OS=Homo sapiens OX=9606 GN=HACD3 PE=1 SV=2 4.25 2785.7 - 995957 - - - -0.0958 - 2.456 0.568 - 401.4 1 2 0 -0.0001 14 0 0 0 1.87E+07 1.64E+07 - - - 5.491 0.9999 221125_WJC_METTL3_EV_vs_WT_F03.15060.15060.2 2.44E-05 20-Nov K.LMIEMDGTENK.S "sp|P06733|ENOA_HUMAN,tr|A0A2R8Y6G6|A0A2R8Y6G6_HUMAN,tr|K7EM90|K7EM90_HUMAN,tr|A0A2R8Y879|A0A2R8Y879_HUMAN,tr|A0A2R8YEM5|A0A2R8YEM5_HUMAN" 5 1279.5788 1.44 30629 15060 2 1279.578743 640.7967 Alpha-enolase OS=Homo sapiens OX=9606 GN=ENO1 PE=1 SV=2 4.14 2785.8 - 3.30E+06 - - - -0.0633 - 2.216 0.534 - 382.6 1 2 0 -0.0001 11 0 0 0 1.69E+08 1.17E+08 - - - 5.1377 0.9998 221125_WJC_METTL3_EV_vs_WT_F03.15061.15061.2 0.000148 20-Oct K.LMIEMDGTENK[136.11].S "sp|P06733|ENOA_HUMAN,tr|A0A2R8Y6G6|A0A2R8Y6G6_HUMAN,tr|K7EM90|K7EM90_HUMAN,tr|A0A2R8Y879|A0A2R8Y879_HUMAN,tr|A0A2R8YEM5|A0A2R8YEM5_HUMAN" 5 1287.593 1.49 30630 15061 2 1287.592858 644.8038 Alpha-enolase OS=Homo sapiens OX=9606 GN=ENO1 PE=1 SV=2 4.14 2785.8 - 2.98E+06 - - - -0.1289 - 2.081 0.414 - 306.5 1 2 0 -0.0002 11 0 0 0 1.80E+08 1.21E+08 - - - 4.0813 0.9999 221125_WJC_METTL3_EV_vs_WT_F03.15062.15062.2 5.26E-06 24-Nov K.IISSNQELIYEGR[166.11].R "sp|Q9UHD2|TBK1_HUMAN,tr|A0A7I2V646|A0A7I2V646_HUMAN,tr|A0A7I2V4Z2|A0A7I2V4Z2_HUMAN,tr|A0A494C079|A0A494C079_HUMAN,tr|A0A494C045|A0A494C045_HUMAN,tr|A0A494C1M6|A0A494C1M6_HUMAN,tr|A0A494C0A8|A0A494C0A8_HUMAN,tr|A0A7I2V4W4|A0A7I2V4W4_HUMAN,tr|A0A7I2V463|A0A7I2V463_HUMAN,tr|A0A494C148|A0A494C148_HUMAN,tr|A0A494C0X2|A0A494C0X2_HUMAN,tr|A0A494C167|A0A494C167_HUMAN,tr|A0A7I2YQG1|A0A7I2YQG1_HUMAN,tr|A0A7I2V3S9|A0A7I2V3S9_HUMAN,tr|A0A494C0R4|A0A494C0R4_HUMAN,tr|A0A7I2V643|A0A7I2V643_HUMAN" 16 1530.7917 3 30631 15062 2 1530.792229 766.4031 Serine\threonine-protein kinase TBK1 OS=Homo sapiens OX=9606 GN=TBK1 PE=1 SV=1 4.53 2785.9 - 661919 - - - 0.3181 - 2.156 0.535 - 357.9 1 2 0 0.0005 13 0 0 0 2.44E+07 8.13E+06 - - - 4.9641 1 221125_WJC_METTL3_EV_vs_WT_F03.15063.15063.2 5.20E-06 13/28 K.LASALLAEQEPQPER.L sp|O95396|MOCS3_HUMAN 1 1650.8577 2.05 30632 15063 2 1650.853709 826.4361 Adenylyltransferase and sulfurtransferase MOCS3 OS=Homo sapiens OX=9606 GN=MOCS3 PE=1 SV=1 4.25 2786.1 - 564728 - - - -2.4175 - 2.929 0.557 - 554.2 1 2 0 -0.004 15 0 0 0 1.21E+07 5.93E+06 - - - 5.7959 0.9998 221125_WJC_METTL3_EV_vs_WT_F03.15064.15064.2 0.000344 13/28 K.LASALLAEQEPQPER[166.11].L sp|O95396|MOCS3_HUMAN 1 1660.866 2.05 30633 15064 2 1660.863569 831.4403 Adenylyltransferase and sulfurtransferase MOCS3 OS=Homo sapiens OX=9606 GN=MOCS3 PE=1 SV=1 4.25 2786.2 - 530996 - - - -1.4456 - 2.636 0.438 - 531.5 1 2 0 -0.0024 15 0 0 0 1.21E+07 5.93E+06 - - - 4.6583 1 221125_WJC_METTL3_EV_vs_WT_F03.15066.15066.3 7.05E-06 14/36 R.R[166.11]VLQALEGLK[136.11].M "sp|P39019|RS19_HUMAN,tr|A0A075B6E2|A0A075B6E2_HUMAN" 2 1143.7095 0.001 30634 15066 3 1143.70885 382.2438 40S ribosomal protein S19 OS=Homo sapiens OX=9606 GN=RPS19 PE=1 SV=2 8.75 2786.4 - 3.01E+07 - - - -0.536 - 2.663 0.472 - 361 1 2 0 -0.0006 10 0 0 0 0.00E+00 7.71E+08 - - - 6.6626 0.9995 221125_WJC_METTL3_EV_vs_WT_F03.15067.15067.2 0.0197 16-Sep K.GQVLNIQMR.R "sp|P05455|LA_HUMAN,tr|E9PGX9|E9PGX9_HUMAN,tr|E7ERC4|E7ERC4_HUMAN" 3 1057.5702 0.84 30635 15067 2 1057.568753 529.7924 Lupus La protein OS=Homo sapiens OX=9606 GN=SSB PE=1 SV=2 9.75 2786.5 - 2.40E+06 - - - -1.4146 - 2.032 0.32 - 404.1 1 2 0 -0.0015 9 0 0 0 3.06E+07 3.63E+07 - - - 3.4553 0.9996 221125_WJC_METTL3_EV_vs_WT_F03.15068.15068.2 0.0036 16-Aug R.ITFDVAPSR.L "sp|Q15155|NOMO1_HUMAN,sp|Q5JPE7|NOMO2_HUMAN,sp|P69849|NOMO3_HUMAN,tr|A0A7I2V686|A0A7I2V686_HUMAN,tr|A0A7I2V3P4|A0A7I2V3P4_HUMAN,tr|A0A7I2V6B0|A0A7I2V6B0_HUMAN,tr|A0A7I2V4D7|A0A7I2V4D7_HUMAN,tr|A0A7I2V4T6|A0A7I2V4T6_HUMAN,tr|A0A0G2JP90|A0A0G2JP90_HUMAN,tr|A0A087X117|A0A087X117_HUMAN,tr|A0A0G2JN29|A0A0G2JN29_HUMAN,tr|A0A7I2V2Z5|A0A7I2V2Z5_HUMAN,tr|A0A087WW46|A0A087WW46_HUMAN,tr|J3KN36|J3KN36_HUMAN" 14 1004.5291 3.68 30636 15068 2 1004.528093 503.2718 Nodal modulator 1 OS=Homo sapiens OX=9606 GN=NOMO1 PE=1 SV=5 5.84 2786.5 - 3.68E+06 - - - -0.9975 - 1.738 0.385 - 268.2 1 2 0 -0.001 9 0 0 0 5.44E+07 1.48E+07 - - - 3.4834 0.9995 221125_WJC_METTL3_EV_vs_WT_F03.15072.15072.2 0.782 13/20 R.DLLHPSLEEEK.K "sp|Q71UM5|RS27L_HUMAN,tr|H0YMV8|H0YMV8_HUMAN,tr|C9JLI6|C9JLI6_HUMAN" 3 1308.6561 2.35 30640 15072 2 1308.656853 655.3353 40S ribosomal protein S27-like OS=Homo sapiens OX=9606 GN=RPS27L PE=1 SV=3 4.4 2787 - 795859 - - - 0.5402 - 1.997 0.305 - 493.6 1 2 0 0.0007 11 0 0 0 3.14E+07 1.34E+07 - - - 3.1646 0.9645 221125_WJC_METTL3_EV_vs_WT_F03.15074.15074.3 0.0229 Oct-36 G.LYFHIGETEK[136.11].R "sp|Q7Z7H5|TMED4_HUMAN,sp|Q9BVK6|TMED9_HUMAN,tr|F8W7F7|F8W7F7_HUMAN" 3 1243.6328 1.09 30642 15074 3 1243.634451 415.5516 Transmembrane emp24 domain-containing protein 4 OS=Homo sapiens OX=9606 GN=TMED4 PE=1 SV=1 5.4 2787.3 - 601975 - - - 1.2962 - 1.937 0.344 - 94.9 1 1 0 0.0016 10 0 0 0 4.02E+07 3.68E+07 - - - 4.3056 0.8772 221125_WJC_METTL3_EV_vs_WT_F03.15078.15078.2 3.68 18-Apr K.LVNEVTEFAK.T "sp|P02768|ALBU_HUMAN,tr|A0A087WWT3|A0A087WWT3_HUMAN,tr|H7C013|H7C013_HUMAN,tr|A0A0C4DGB6|A0A0C4DGB6_HUMAN" 4 1148.6077 350.36 30644 15078 2 1148.607161 575.3111 Albumin OS=Homo sapiens OX=9606 GN=ALB PE=1 SV=2 4.53 2787.8 - 1.00E+07 - - - -0.5041 - 0.921 0.083 - 45.3 10 2 0 -0.0006 10 0 0 0 2.46E+08 7.01E+05 - - - -1.0226 0.9999 221125_WJC_METTL3_EV_vs_WT_F03.15082.15082.2 0.000271 18-Dec K.VENLVDQLNK[136.11].S "sp|Q15643|TRIPB_HUMAN,tr|H0YJ97|H0YJ97_HUMAN" 2 1178.6387 1.28 30648 15082 2 1178.639758 590.3266 Thyroid receptor-interacting protein 11 OS=Homo sapiens OX=9606 GN=TRIP11 PE=1 SV=3 4.37 2788 - 1.46E+06 - - - 0.9384 - 2.472 0.47 - 695.2 1 2 0 0.0011 10 0 0 0 4.68E+07 3.65E+07 - - - 5.0383 0.9999 221125_WJC_METTL3_EV_vs_WT_F03.15083.15083.2 2.60E-05 16-Sep R.DDAYWPEAK.R "sp|Q15424|SAFB1_HUMAN,tr|K7EII0|K7EII0_HUMAN" 2 1093.4716 1.46 30649 15083 2 1093.471388 547.7431 Scaffold attachment factor B1 OS=Homo sapiens OX=9606 GN=SAFB PE=1 SV=4 4.03 2788.1 - 1.07E+06 - - - -0.2305 - 1.738 0.523 - 402.5 1 2 0 -0.0003 9 0 0 0 4.75E+07 3.26E+07 - - - 4.5029 0.9889 221125_WJC_METTL3_EV_vs_WT_F03.15086.15086.2 1.73E-05 13/20 R.DLLHPSLEEEK[136.11].K "sp|Q71UM5|RS27L_HUMAN,tr|H0YMV8|H0YMV8_HUMAN,tr|C9JLI6|C9JLI6_HUMAN" 3 1316.6703 2.27 30652 15086 2 1316.663907 659.3424 40S ribosomal protein S27-like OS=Homo sapiens OX=9606 GN=RPS27L PE=1 SV=3 4.4 2788.5 - 953487 - - - -4.8904 - 2.251 0.211 - 408.5 1 2 0 -0.0064 11 0 0 0 2.80E+07 1.24E+07 - - - 2.7924 1 221125_WJC_METTL3_EV_vs_WT_F03.15089.15089.2 2.70E-07 24-Dec K.ILDSVGIEADDDR.L sp|P05387|RLA2_HUMAN 1 1416.6733 1.55 30655 15089 2 1416.660471 709.3439 60S acidic ribosomal protein P2 OS=Homo sapiens OX=9606 GN=RPLP2 PE=1 SV=1 3.71 2788.9 - 477294 - - - -9.0225 - 2.627 0.57 - 445.6 1 2 0 -0.0128 13 0 0 0 5.55E+08 3.59E+08 - - - 5.7259 0.9872 221125_WJC_METTL3_EV_vs_WT_F03.15090.15090.2 1.32E-05 26-Dec Q.QIGQVNNAATLDLK.N "sp|Q2KHR3|QSER1_HUMAN,tr|A0A3B3IRW6|A0A3B3IRW6_HUMAN" 2 1483.7995 2.1 30656 15090 2 1483.799951 742.907 Glutamine and serine-rich protein 1 OS=Homo sapiens OX=9606 GN=QSER1 PE=1 SV=3 5.84 2789 - 363714 - - - 0.3329 - 2.129 0.42 - 322.4 1 1 0 0.0005 14 0 0 0 1.02E+07 4.84E+06 - - - 4.0392 0.9952 221125_WJC_METTL3_EV_vs_WT_F03.15092.15092.3 0.0711 Dec-36 R.TIR[166.11]YPDPLIK[136.11].V "sp|P62701|RS4X_HUMAN,sp|Q8TD47|RS4Y2_HUMAN" 2 1232.7248 0.97 30657 15092 3 1232.724044 411.9155 "40S ribosomal protein S4, X isoform OS=Homo sapiens OX=9606 GN=RPS4X PE=1 SV=2" 8.25 2789.2 - 4.65E+06 - - - -0.5962 - 2.037 0.238 - 208.9 1 2 1 -0.0007 10 0 0 0 1.56E+08 1.61E+08 - - - 3.2711 0.998 221125_WJC_METTL3_EV_vs_WT_F03.15096.15096.2 1.09 20-Aug K.NILTSNNIDVK.K "sp|P05090|APOD_HUMAN,tr|C9JF17|C9JF17_HUMAN" 2 1229.6616 45.13 30660 15096 2 1229.6616 615.8381 Apolipoprotein D OS=Homo sapiens OX=9606 GN=APOD PE=1 SV=1 5.84 2789.6 - 3.86E+06 - - - 0.0276 - 1.667 0.184 - 132.1 1 2 0 0 11 0 0 0 9.02E+07 2.00E+06 - - - 1.7825 0.9998 221125_WJC_METTL3_EV_vs_WT_F03.15097.15097.2 0.001 18-Oct K.VENLVDQLNK.S "sp|Q15643|TRIPB_HUMAN,tr|H0YJ97|H0YJ97_HUMAN" 2 1170.6245 1.1 30661 15097 2 1170.625343 586.3195 Thyroid receptor-interacting protein 11 OS=Homo sapiens OX=9606 GN=TRIP11 PE=1 SV=3 4.37 2789.6 - 2.84E+06 - - - 0.7611 - 2.329 0.42 - 418.6 1 2 0 0.0009 10 0 0 0 4.83E+07 4.37E+07 - - - 4.5027 1 221125_WJC_METTL3_EV_vs_WT_F03.15098.15098.2 0.000454 14/24 R.LAVQQVEEAQQLR.E "sp|O00461|GOLI4_HUMAN,tr|F8W785|F8W785_HUMAN" 2 1510.8104 1.48 30662 15098 2 1510.810225 756.4125 Golgi integral membrane protein 4 OS=Homo sapiens OX=9606 GN=GOLIM4 PE=1 SV=1 4.53 2789.7 - 2.09E+06 - - - -0.0867 - 3.132 0.539 - 943 1 2 0 -0.0001 13 0 0 0 5.09E+07 3.43E+07 - - - 5.9521 0.9966 221125_WJC_METTL3_EV_vs_WT_F03.15099.15099.2 0.000194 22-Dec R.QLLDDEEQLTAK[136.11].T sp|Q9BSJ8|ESYT1_HUMAN 1 1409.7129 0.86 30663 15099 2 1409.705539 705.8637 Extended synaptotagmin-1 OS=Homo sapiens OX=9606 GN=ESYT1 PE=1 SV=1 3.92 2789.7 - 1.91E+06 - - - -5.25 - 2.389 0.434 - 528.4 1 2 0 -0.0074 12 0 0 0 2.36E+07 2.74E+07 - - - 4.5356 1 221125_WJC_METTL3_EV_vs_WT_F03.15102.15102.2 4.47E-10 17/32 K.VLQSEGEAVDPEANVIK.Q "sp|Q8IWI9|MGAP_HUMAN,tr|H3BU53|H3BU53_HUMAN" 2 1796.9156 3.32 30666 15102 2 1796.918762 899.4651 MAX gene-associated protein OS=Homo sapiens OX=9606 GN=MGA PE=1 SV=4 4 2790.1 - 584327 - - - 1.7547 - 3.18 0.653 - 727.8 1 2 0 0.0032 17 0 0 0 8.14E+06 2.45E+06 - - - 6.7073 1 221125_WJC_METTL3_EV_vs_WT_F03.15105.15105.2 1.54E-06 14/22 R.QLLDDEEQLTAK.T sp|Q9BSJ8|ESYT1_HUMAN 1 1401.6987 0.8 30668 15105 2 1401.700424 701.8566 Extended synaptotagmin-1 OS=Homo sapiens OX=9606 GN=ESYT1 PE=1 SV=1 3.92 2790.5 - 1.41E+06 - - - 1.2014 - 2.76 0.621 - 790.4 1 2 0 0.0017 12 0 0 0 2.36E+07 2.94E+07 - - - 6.2984 0.9998 221125_WJC_METTL3_EV_vs_WT_F03.15107.15107.2 0.000483 22-Nov K.GEFGGFGSVSGK[136.11].L "sp|Q09028|RBBP4_HUMAN,tr|C9JPP3|C9JPP3_HUMAN" 2 1135.5389 1.56 30669 15107 2 1135.539015 568.7767 Histone-binding protein RBBP4 OS=Homo sapiens OX=9606 GN=RBBP4 PE=1 SV=3 6 2790.7 - 4.20E+06 - - - 0.0678 - 1.913 0.468 - 261.5 1 2 0 0.0001 12 0 0 0 9.15E+07 5.87E+07 - - - 4.2044 0.8401 221125_WJC_METTL3_EV_vs_WT_F03.15108.15108.3 0.00381 Nov-36 G.LYFHIGETEK.R "sp|Q7Z7H5|TMED4_HUMAN,sp|Q9BVK6|TMED9_HUMAN,tr|F8W7F7|F8W7F7_HUMAN" 3 1235.6186 1.1 30670 15108 3 1235.617782 412.8802 Transmembrane emp24 domain-containing protein 4 OS=Homo sapiens OX=9606 GN=TMED4 PE=1 SV=1 5.4 2790.8 - 2.90E+06 - - - -0.6936 - 1.78 0.24 - 139.4 1 1 0 -0.0009 10 0 0 0 4.11E+07 3.73E+07 - - - 2.8995 0.9326 221125_WJC_METTL3_EV_vs_WT_F03.15109.15109.3 0.969 Nov-48 K.LLEAFHNQGPVIK.R "sp|Q9Y2R9|RT07_HUMAN,tr|J3QLS3|J3QLS3_HUMAN,tr|J3QQS1|J3QQS1_HUMAN,tr|J3KSI8|J3KSI8_HUMAN" 4 1464.8089 0.67 30671 15109 3 1464.808431 489.2769 "28S ribosomal protein S7, mitochondrial OS=Homo sapiens OX=9606 GN=MRPS7 PE=1 SV=2" 6.75 2790.8 - 3.78E+06 - - - -0.3195 - 1.939 0.031 - 141.5 1 2 0 -0.0005 13 0 0 0 4.39E+07 6.53E+07 - - - 0.6808 0.9999 221125_WJC_METTL3_EV_vs_WT_F03.15110.15110.3 0.000116 Nov-48 R.LAVQQVEEAQQLR.E "sp|O00461|GOLI4_HUMAN,tr|F8W785|F8W785_HUMAN" 2 1510.8104 1.42 30672 15110 3 1510.810357 504.6107 Golgi integral membrane protein 4 OS=Homo sapiens OX=9606 GN=GOLIM4 PE=1 SV=1 4.53 2790.9 - 3.06E+06 - - - 0.0007 - 2.462 0.359 - 236.2 1 2 0 0 13 0 0 0 4.83E+07 3.39E+07 - - - 4.9853 0.9992 221125_WJC_METTL3_EV_vs_WT_F03.15111.15111.2 1.07E-07 16/24 R.LAVQQVEEAQQLR[166.11].E "sp|O00461|GOLI4_HUMAN,tr|F8W785|F8W785_HUMAN" 2 1520.8186 1.48 30673 15111 2 1520.824658 761.4166 Golgi integral membrane protein 4 OS=Homo sapiens OX=9606 GN=GOLIM4 PE=1 SV=1 4.53 2791 - 1.75E+06 - - - 3.9663 - 3.129 0.5 - 1153.4 1 2 0 0.006 13 0 0 0 5.09E+07 3.43E+07 - - - 5.6598 0.9994 221125_WJC_METTL3_EV_vs_WT_F03.15112.15112.2 0.0232 16-Aug R.DDAYWPEAK[136.11].R "sp|Q15424|SAFB1_HUMAN,tr|K7EII0|K7EII0_HUMAN" 2 1101.4858 1.46 30674 15112 2 1101.486081 551.7502 Scaffold attachment factor B1 OS=Homo sapiens OX=9606 GN=SAFB PE=1 SV=4 4.03 2791 - 1.43E+06 - - - 0.2188 - 1.57 0.352 - 286.1 1 2 0 0.0002 9 0 0 0 4.73E+07 3.23E+07 - - - 2.9458 0.9997 221125_WJC_METTL3_EV_vs_WT_F03.15114.15114.2 0.0192 14-Oct R.EEDFPSLR.E sp|P51948|MAT1_HUMAN 1 991.4611 1.37 30676 15114 2 991.460896 496.7378 CDK-activating kinase assembly factor MAT1 OS=Homo sapiens OX=9606 GN=MNAT1 PE=1 SV=1 4.14 2791.2 - 968347 - - - -0.1805 - 1.943 0.366 - 378.2 1 2 0 -0.0002 8 0 0 0 4.08E+07 2.99E+07 - - - 3.7475 1 221125_WJC_METTL3_EV_vs_WT_F03.15115.15115.2 1.48E-08 13/24 R.VLSNSGWGQTPIK.Q sp|Q8NDV7|TNR6A_HUMAN 1 1385.7303 1.64 30677 15115 2 1385.725243 693.8724 Trinucleotide repeat-containing gene 6A protein OS=Homo sapiens OX=9606 GN=TNRC6A PE=1 SV=2 8.72 2791.4 - 753293 - - - -3.6594 - 2.486 0.593 - 507.2 1 2 0 -0.0051 13 0 0 0 9.05E+06 5.53E+06 - - - 5.7566 0.9994 221125_WJC_METTL3_EV_vs_WT_F03.15116.15116.2 0.00233 16-Sep R.VFNYNTLER[166.11].V "sp|P35606|COPB2_HUMAN,tr|H0Y938|H0Y938_HUMAN,tr|A0A7I2V3G0|A0A7I2V3G0_HUMAN,tr|D6RBZ7|D6RBZ7_HUMAN,tr|A0A7I2V258|A0A7I2V258_HUMAN,tr|D6R997|D6R997_HUMAN,tr|D6RBT6|D6RBT6_HUMAN,tr|H0YAC7|H0YAC7_HUMAN,tr|D6RBG7|D6RBG7_HUMAN,tr|A0A7I2YQF9|A0A7I2YQF9_HUMAN,tr|D6RCL6|D6RCL6_HUMAN" 11 1164.5803 1.06 30678 15116 2 1164.578365 583.2974 Coatomer subunit beta' OS=Homo sapiens OX=9606 GN=COPB2 PE=1 SV=2 5.97 2791.5 - 748555 - - - -1.6555 - 1.686 0.393 - 241.2 1 2 0 -0.0019 9 0 0 0 7.54E+06 7.10E+06 - - - 3.4543 0.9998 221125_WJC_METTL3_EV_vs_WT_F03.15120.15120.2 0.00021 18-Nov R.QVLDNLTMEK.S "sp|P35527|K1C9_HUMAN,tr|K7EQQ3|K7EQQ3_HUMAN" 2 1189.6013 4482.94 30680 15120 2 1189.601648 595.8079 "Keratin, type I cytoskeletal 9 OS=Homo sapiens OX=9606 GN=KRT9 PE=1 SV=3" 4.37 2792 - 1.04E+07 - - - 0.3144 - 2.186 0.451 - 486 1 2 0 0.0004 10 0 0 0 4.61E+09 1.03E+06 - - - 4.555 0.9998 221125_WJC_METTL3_EV_vs_WT_F03.15121.15121.2 6.18E-07 20-Nov K.ELVEFAQDDDR[166.11].L sp|Q14677|EPN4_HUMAN 1 1345.6025 2.04 30681 15121 2 1345.600046 673.8085 Clathrin interactor 1 OS=Homo sapiens OX=9606 GN=CLINT1 PE=1 SV=1 3.77 2792.1 - 3.98E+06 - - - -1.8564 - 2.389 0.561 - 544 1 2 0 -0.0025 11 0 0 0 1.18E+08 5.80E+07 - - - 5.5397 1 221125_WJC_METTL3_EV_vs_WT_F03.15122.15122.2 1.41E-07 24-Dec K.ILDSVGIEADDDR[166.11].L sp|P05387|RLA2_HUMAN 1 1426.6815 1.55 30682 15122 2 1426.679368 714.348 60S acidic ribosomal protein P2 OS=Homo sapiens OX=9606 GN=RPLP2 PE=1 SV=1 3.71 2792.1 - 3.77E+06 - - - -1.5105 - 2.626 0.619 - 544.9 1 2 0 -0.0022 13 0 0 0 5.53E+08 3.57E+08 - - - 6.0901 0.9998 221125_WJC_METTL3_EV_vs_WT_F03.15126.15126.2 7.19E-06 14/22 R.QLVDTTVELANK.V sp|O75533|SF3B1_HUMAN 1 1329.714 1.35 30686 15126 2 1329.715411 665.8643 Splicing factor 3B subunit 1 OS=Homo sapiens OX=9606 GN=SF3B1 PE=1 SV=3 4.37 2792.4 - 1.59E+06 - - - 1.0641 - 2.403 0.454 - 367.2 1 2 0 0.0014 12 0 0 0 6.76E+07 5.01E+07 - - - 4.7006 0.9973 221125_WJC_METTL3_EV_vs_WT_F03.15128.15128.2 0.021 14-Jul R.DYFEEYGK[136.11].L "sp|P22626|ROA2_HUMAN,tr|A0A7I2YQN4|A0A7I2YQN4_HUMAN,tr|A0A7I2V4N0|A0A7I2V4N0_HUMAN,tr|A0A024RA28|A0A024RA28_HUMAN,tr|A0A7I2V4N1|A0A7I2V4N1_HUMAN,tr|A0A7I2V4I6|A0A7I2V4I6_HUMAN,tr|A0A087WUI2|A0A087WUI2_HUMAN,tr|A0A7I2V4S4|A0A7I2V4S4_HUMAN,tr|A0A7I2V323|A0A7I2V323_HUMAN,tr|A0A7I2V3P1|A0A7I2V3P1_HUMAN,tr|A0A7I2V3P7|A0A7I2V3P7_HUMAN" 11 1057.4484 1.38 30688 15128 2 1057.448274 529.7315 Heterogeneous nuclear ribonucleoproteins A2\B1 OS=Homo sapiens OX=9606 GN=HNRNPA2B1 PE=1 SV=2 4.14 2792.7 - 1.14E+06 - - - -0.1116 - 1.297 0.234 - 176.7 1 2 0 -0.0001 8 0 0 0 5.85E+08 4.24E+08 - - - 1.5536 0.9068 221125_WJC_METTL3_EV_vs_WT_F03.15131.15131.2 0.0635 16-Aug M.ASGFVDFSK[136.11].G "sp|Q8IWZ3|ANKH1_HUMAN,tr|A0A0A0MQZ8|A0A0A0MQZ8_HUMAN,tr|H0Y7Y3|H0Y7Y3_HUMAN,tr|H0Y4P6|H0Y4P6_HUMAN,tr|H7C2E1|H7C2E1_HUMAN" 5 964.4745 1.51 30691 15131 2 964.47367 483.2445 Ankyrin repeat and KH domain-containing protein 1 OS=Homo sapiens OX=9606 GN=ANKHD1 PE=1 SV=1 5.88 2793 - 580931 - - - -0.9093 - 1.395 0.275 - 194 1 1 0 -0.0009 9 0 0 0 1.26E+07 8.40E+06 - - - 2.035 1 221125_WJC_METTL3_EV_vs_WT_F03.15132.15132.2 3.11E-11 16/26 K.MSNALAIQVDSEGK.L "sp|Q13573|SNW1_HUMAN,tr|G3V3A4|G3V3A4_HUMAN,tr|G3V5R3|G3V5R3_HUMAN" 3 1461.7133 2.71 30692 15132 2 1461.711911 731.8639 SNW domain-containing protein 1 OS=Homo sapiens OX=9606 GN=SNW1 PE=1 SV=1 4.37 2793.2 - 451360 - - - -0.9804 - 3.323 0.683 - 1045.5 1 2 0 -0.0014 14 0 0 0 1.42E+07 5.23E+06 - - - 7.0987 0.9946 221125_WJC_METTL3_EV_vs_WT_F03.15137.15137.3 0.337 Sep-36 R.LEELHVIDVK[136.11].F "sp|Q16531|DDB1_HUMAN,tr|F5GWI0|F5GWI0_HUMAN,tr|F5H2L3|F5H2L3_HUMAN,tr|A0A7P0TAK7|A0A7P0TAK7_HUMAN,tr|A0A7P0Z3Z5|A0A7P0Z3Z5_HUMAN,tr|F5GY55|F5GY55_HUMAN,tr|A0A7P0Z4B9|A0A7P0Z4B9_HUMAN,tr|A0A7P0Z4L2|A0A7P0Z4L2_HUMAN,tr|A0A7P0T965|A0A7P0T965_HUMAN" 9 1201.6798 0.21 30695 15137 3 1201.679642 401.5672 DNA damage-binding protein 1 OS=Homo sapiens OX=9606 GN=DDB1 PE=1 SV=1 4.65 2793.7 - 3.35E+06 - - - -0.1223 - 1.443 0.231 - 77.8 1 2 0 -0.0001 10 0 0 0 1.05E+07 4.95E+07 - - - 2.1864 0.9996 221125_WJC_METTL3_EV_vs_WT_F03.15138.15138.2 0.00499 14-Jun R.DYFEEYGK.L "sp|P22626|ROA2_HUMAN,tr|A0A7I2YQN4|A0A7I2YQN4_HUMAN,tr|A0A7I2V4N0|A0A7I2V4N0_HUMAN,tr|A0A024RA28|A0A024RA28_HUMAN,tr|A0A7I2V4N1|A0A7I2V4N1_HUMAN,tr|A0A7I2V4I6|A0A7I2V4I6_HUMAN,tr|A0A087WUI2|A0A087WUI2_HUMAN,tr|A0A7I2V4S4|A0A7I2V4S4_HUMAN,tr|A0A7I2V323|A0A7I2V323_HUMAN,tr|A0A7I2V3P1|A0A7I2V3P1_HUMAN,tr|A0A7I2V3P7|A0A7I2V3P7_HUMAN" 11 1049.4342 1.38 30696 15138 2 1049.433863 525.7244 Heterogeneous nuclear ribonucleoproteins A2\B1 OS=Homo sapiens OX=9606 GN=HNRNPA2B1 PE=1 SV=2 4.14 2793.8 - 3.28E+06 - - - -0.3135 - 1.283 0.473 - 114.8 1 2 0 -0.0003 8 0 0 0 5.85E+08 4.24E+08 - - - 3.2861 0.9999 221125_WJC_METTL3_EV_vs_WT_F03.15139.15139.3 0.00051 Aug-32 K.FYVHNDMFR.Y "sp|Q9UN86|G3BP2_HUMAN,tr|A0A7I2V3E2|A0A7I2V3E2_HUMAN,tr|A0A7I2V647|A0A7I2V647_HUMAN,tr|H0YAE3|H0YAE3_HUMAN,tr|D6RAC7|D6RAC7_HUMAN,tr|D6RB17|D6RB17_HUMAN,tr|A0A7I2YQS2|A0A7I2YQS2_HUMAN,tr|A0A7I2YQD9|A0A7I2YQD9_HUMAN,tr|A0A7I2V3R7|A0A7I2V3R7_HUMAN,tr|A0A7I2V481|A0A7I2V481_HUMAN,tr|A0A7I2V3P9|A0A7I2V3P9_HUMAN" 11 1227.5495 1.38 30697 15139 3 1227.548986 410.1904 Ras GTPase-activating protein-binding protein 2 OS=Homo sapiens OX=9606 GN=G3BP2 PE=1 SV=2 6.74 2793.9 - 2.46E+06 - - - -0.4293 - 1.663 0.503 - 85.4 1 2 0 -0.0005 9 0 0 0 2.44E+08 1.77E+08 - - - 5.6807 0.9999 221125_WJC_METTL3_EV_vs_WT_F03.15141.15141.2 9.21E-06 22-Dec K.GGPGSTLSFVGK[136.11].R sp|Q9BQ61|TRIR_HUMAN 1 1113.591 0.44 30699 15141 2 1113.592301 557.8028 Telomerase RNA component interacting RNase OS=Homo sapiens OX=9606 GN=TRIR PE=1 SV=1 8.75 2794 - 1.80E+06 - - - 1.1916 - 2.322 0.547 - 559.4 1 2 0 0.0013 12 0 0 0 1.85E+07 4.17E+07 - - - 5.2973 0.9999 221125_WJC_METTL3_EV_vs_WT_F03.15143.15143.2 0.00404 13/22 R.QLLLQQQTSGLK.S "sp|O15409|FOXP2_HUMAN,tr|Q8N6B5|Q8N6B5_HUMAN,tr|A0A0U1RQE0|A0A0U1RQE0_HUMAN,tr|A0A0U1RQR8|A0A0U1RQR8_HUMAN,tr|A8MUV4|A8MUV4_HUMAN,tr|A0A0U1RQM2|A0A0U1RQM2_HUMAN,tr|C9JQP8|C9JQP8_HUMAN,tr|A0A0U1RQY3|A0A0U1RQY3_HUMAN" 8 1355.7773 6.03 30701 15143 2 1355.776516 678.8959 Forkhead box protein P2 OS=Homo sapiens OX=9606 GN=FOXP2 PE=1 SV=2 8.75 2794.2 - 1.66E+06 - - - -0.5525 - 2.399 0.474 - 816.1 1 2 0 -0.0007 12 0 0 0 2.45E+07 4.06E+06 - - - 4.8441 0.9998 221125_WJC_METTL3_EV_vs_WT_F03.15144.15144.2 0.0154 20-Dec K.ALLEVVQSGGK[136.11].N "sp|Q8TAA3|PSMA8_HUMAN,sp|O14818|PSA7_HUMAN,tr|A0A087WYS6|A0A087WYS6_HUMAN" 3 1107.6379 0.73 30702 15144 2 1107.637324 554.8262 Proteasome subunit alpha-type 8 OS=Homo sapiens OX=9606 GN=PSMA8 PE=2 SV=3 6.05 2794.3 - 1.66E+06 - - - -0.5417 - 2.249 0.363 - 477.2 1 2 0 -0.0006 11 0 0 0 9.10E+07 1.25E+08 - - - 3.9145 0.9994 221125_WJC_METTL3_EV_vs_WT_F03.15145.15145.2 0.00514 14-Aug R.EEDFPSLR[166.11].E sp|P51948|MAT1_HUMAN 1 1001.4693 1.4 30703 15145 2 1001.470178 501.7419 CDK-activating kinase assembly factor MAT1 OS=Homo sapiens OX=9606 GN=MNAT1 PE=1 SV=1 4.14 2794.3 - 1.34E+06 - - - 0.8318 - 1.393 0.404 - 232.2 1 2 0 0.0008 8 0 0 0 4.05E+07 2.89E+07 - - - 3.0243 0.9999 221125_WJC_METTL3_EV_vs_WT_F03.15146.15146.3 0.00408 13/40 R.ITAAVIEHLER.L "sp|O43716|GATC_HUMAN,tr|H0YIV9|H0YIV9_HUMAN,tr|F8VRU3|F8VRU3_HUMAN" 3 1250.6983 0.66 30704 15146 3 1250.697796 417.9067 "Glutamyl-tRNA(Gln) amidotransferase subunit C, mitochondrial OS=Homo sapiens OX=9606 GN=GATC PE=1 SV=1" 5.4 2794.4 - 830830 - - - -0.3918 - 2.091 0.38 - 173.2 1 2 0 -0.0005 11 0 0 0 1.05E+07 1.59E+07 - - - 4.872 0.9999 221125_WJC_METTL3_EV_vs_WT_F03.15147.15147.3 0.000289 14/40 K.TNLLLQAHLSR.M sp|O75643|U520_HUMAN 1 1264.7252 2.53 30705 15147 3 1264.723166 422.5823 U5 small nuclear ribonucleoprotein 200 kDa helicase OS=Homo sapiens OX=9606 GN=SNRNP200 PE=1 SV=2 9.44 2794.5 - 772679 - - - -1.5837 - 2.652 0.374 - 399.3 1 2 0 -0.002 11 0 0 0 8.65E+07 3.42E+07 - - - 5.4799 0.9735 221125_WJC_METTL3_EV_vs_WT_F03.15148.15148.2 0.000437 16-Aug M.ASGFVDFSK.G "sp|Q8IWZ3|ANKH1_HUMAN,tr|A0A0A0MQZ8|A0A0A0MQZ8_HUMAN,tr|H0Y7Y3|H0Y7Y3_HUMAN,tr|H0Y4P6|H0Y4P6_HUMAN,tr|H7C2E1|H7C2E1_HUMAN" 5 956.4603 1.57 30706 15148 2 956.461482 479.2374 Ankyrin repeat and KH domain-containing protein 1 OS=Homo sapiens OX=9606 GN=ANKHD1 PE=1 SV=1 5.88 2794.6 - 740909 - - - 1.1867 - 1.676 0.405 - 203.9 1 1 0 0.0011 9 0 0 0 1.34E+07 8.52E+06 - - - 3.526 0.9996 221125_WJC_METTL3_EV_vs_WT_F03.15150.15150.3 4.39E-05 13/52 R.VLHVSENPVPLTVR.V sp|Q8N1G4|LRC47_HUMAN 1 1558.8831 0.85 30708 15150 3 1558.877932 520.635 Leucine-rich repeat-containing protein 47 OS=Homo sapiens OX=9606 GN=LRRC47 PE=1 SV=1 6.72 2794.9 - 537749 - - - -3.3325 - 2.374 0.402 - 171.8 1 2 0 -0.0052 14 0 0 0 4.25E+07 5.01E+07 - - - 5.3181 0.9989 221125_WJC_METTL3_EV_vs_WT_F03.15152.15152.2 0.000345 13/28 K.C[160.03]LLAASPENEAGGLK.L sp|Q9NW13|RBM28_HUMAN 1 1528.7555 1.16 30710 15152 2 1528.761137 765.385 RNA-binding protein 28 OS=Homo sapiens OX=9606 GN=RBM28 PE=1 SV=3 4.53 2795.2 - 244426 - - - 3.6592 - 2.45 0.442 - 446.5 1 2 0 0.0056 15 0 0 0 2.04E+06 1.76E+06 - - - 4.5069 0.9999 221125_WJC_METTL3_EV_vs_WT_F03.15156.15156.3 0.000526 Nov-32 K.FYVHNDMFR[166.11].Y "sp|Q9UN86|G3BP2_HUMAN,tr|A0A7I2V3E2|A0A7I2V3E2_HUMAN,tr|A0A7I2V647|A0A7I2V647_HUMAN,tr|H0YAE3|H0YAE3_HUMAN,tr|D6RAC7|D6RAC7_HUMAN,tr|D6RB17|D6RB17_HUMAN,tr|A0A7I2YQS2|A0A7I2YQS2_HUMAN,tr|A0A7I2YQD9|A0A7I2YQD9_HUMAN,tr|A0A7I2V3R7|A0A7I2V3R7_HUMAN,tr|A0A7I2V481|A0A7I2V481_HUMAN,tr|A0A7I2V3P9|A0A7I2V3P9_HUMAN" 11 1237.5578 1.38 30712 15156 3 1237.557403 413.5265 Ras GTPase-activating protein-binding protein 2 OS=Homo sapiens OX=9606 GN=G3BP2 PE=1 SV=2 6.74 2795.6 - 6.47E+06 - - - -0.3071 - 1.972 0.417 - 141.2 1 2 0 -0.0004 9 0 0 0 2.44E+08 1.77E+08 - - - 5.2355 0.9986 221125_WJC_METTL3_EV_vs_WT_F03.15157.15157.2 0.0102 20-Dec K.ALLEVVQSGGK.N "sp|Q8TAA3|PSMA8_HUMAN,sp|O14818|PSA7_HUMAN,tr|A0A087WYS6|A0A087WYS6_HUMAN" 3 1099.6237 0.6 30713 15157 2 1099.623853 550.8191 Proteasome subunit alpha-type 8 OS=Homo sapiens OX=9606 GN=PSMA8 PE=2 SV=3 6.05 2795.6 - 2.39E+06 - - - 0.1173 - 2.125 0.139 - 437.4 1 2 0 0.0001 11 0 0 0 9.47E+07 1.58E+08 - - - 2.1067 0.9999 221125_WJC_METTL3_EV_vs_WT_F03.15158.15158.3 0.0257 15/40 K.TNLLLQAHLSR[166.11].M sp|O75643|U520_HUMAN 1 1274.7334 2.53 30714 15158 3 1274.732978 425.9184 U5 small nuclear ribonucleoprotein 200 kDa helicase OS=Homo sapiens OX=9606 GN=SNRNP200 PE=1 SV=2 9.44 2795.7 - 1.23E+06 - - - -0.3616 - 2.825 0.372 - 434.7 1 2 0 -0.0005 11 0 0 0 8.65E+07 3.42E+07 - - - 5.6375 0.9997 221125_WJC_METTL3_EV_vs_WT_F03.15160.15160.2 0.00355 16-Sep K.FYVHNDMFR[166.11].Y "sp|Q9UN86|G3BP2_HUMAN,tr|A0A7I2V3E2|A0A7I2V3E2_HUMAN,tr|A0A7I2V647|A0A7I2V647_HUMAN,tr|H0YAE3|H0YAE3_HUMAN,tr|D6RAC7|D6RAC7_HUMAN,tr|D6RB17|D6RB17_HUMAN,tr|A0A7I2YQS2|A0A7I2YQS2_HUMAN,tr|A0A7I2YQD9|A0A7I2YQD9_HUMAN,tr|A0A7I2V3R7|A0A7I2V3R7_HUMAN,tr|A0A7I2V481|A0A7I2V481_HUMAN,tr|A0A7I2V3P9|A0A7I2V3P9_HUMAN" 11 1237.5578 1.49 30716 15160 2 1237.559415 619.7862 Ras GTPase-activating protein-binding protein 2 OS=Homo sapiens OX=9606 GN=G3BP2 PE=1 SV=2 6.74 2795.9 - 966548 - - - 1.3187 - 1.595 0.486 - 325.2 1 2 0 0.0016 9 0 0 0 3.65E+07 2.44E+07 - - - 3.9808 0.9996 221125_WJC_METTL3_EV_vs_WT_F03.15161.15161.2 0.00035 24-Nov K.MLQGESAEAFVAK.H sp|Q9NYH9|UTP6_HUMAN 1 1379.6755 1.98 30717 15161 2 1379.677329 690.845 U3 small nucleolar RNA-associated protein 6 homolog OS=Homo sapiens OX=9606 GN=UTP6 PE=1 SV=2 4.53 2796.1 - 815776 - - - 1.3242 - 1.871 0.41 - 324.4 1 2 0 0.0018 13 0 0 0 6.89E+06 3.47E+06 - - - 3.6765 0.9997 221125_WJC_METTL3_EV_vs_WT_F03.15164.15164.2 0.000802 14-Aug K.GNEILELK.C sp|P12270|TPR_HUMAN 1 914.5073 4.74 30720 15164 2 914.507302 458.2609 Nucleoprotein TPR OS=Homo sapiens OX=9606 GN=TPR PE=1 SV=3 4.53 2796.4 - 696046 - - - 0.0055 - 1.718 0.372 - 202.9 1 2 0 0 8 0 0 0 1.94E+07 4.08E+06 - - - 3.4207 0.9798 221125_WJC_METTL3_EV_vs_WT_F03.15167.15167.2 2.54 18-Aug K.IPQAIAQLSK.E "sp|Q16795|NDUA9_HUMAN,tr|A0A3B3ISG8|A0A3B3ISG8_HUMAN" 2 1067.6339 0.64 30723 15167 2 1067.635402 534.8242 "NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 9, mitochondrial OS=Homo sapiens OX=9606 GN=NDUFA9 PE=1 SV=2" 8.75 2796.8 - 359839 - - - 1.4115 - 1.394 0.097 - 108.1 3 2 0 0.0015 10 0 0 0 2.22E+06 3.49E+06 - - - 0.471 0.9996 221125_WJC_METTL3_EV_vs_WT_F03.15169.15169.2 0.000674 20-Sep R.NLPLPPPPPPR.G "sp|P61978|HNRPK_HUMAN,tr|Q5T6W2|Q5T6W2_HUMAN" 2 1193.6921 1.55 30724 15169 2 1193.693538 597.8533 Heterogeneous nuclear ribonucleoprotein K OS=Homo sapiens OX=9606 GN=HNRNPK PE=1 SV=1 9.75 2797.1 - 9.22E+06 - - - 1.2231 - 1.729 0.443 - 274.9 1 2 0 0.0015 11 0 0 0 2.59E+08 1.67E+08 - - - 3.7938 0.9969 221125_WJC_METTL3_EV_vs_WT_F03.15170.15170.2 0.152 14-Sep K.DQIIDSLK.R "sp|Q6P3W7|SCYL2_HUMAN,tr|F8VSC5|F8VSC5_HUMAN,tr|A0A0U1RQQ9|A0A0U1RQQ9_HUMAN" 3 930.5022 9.06 30725 15170 2 930.503468 466.2584 SCY1-like protein 2 OS=Homo sapiens OX=9606 GN=SCYL2 PE=1 SV=1 4.21 2797.2 - 1.66E+06 - - - 1.3498 - 1.493 0.21 - 404.4 1 2 0 0.0013 8 0 0 0 1.17E+08 1.29E+07 - - - 1.8004 0.9993 221125_WJC_METTL3_EV_vs_WT_F03.15171.15171.2 7.44E-05 22-Oct R.ELDATATVLANR.Q "sp|Q13948|CASP_HUMAN,sp|P39880|CUX1_HUMAN,tr|A0A2R8Y852|A0A2R8Y852_HUMAN,tr|A0A2R8YDI1|A0A2R8YDI1_HUMAN" 4 1272.6674 3.11 30726 15171 2 1272.667651 637.341 Protein CASP OS=Homo sapiens OX=9606 GN=CUX1 PE=1 SV=2 4.37 2797.2 - 1.03E+07 - - - 0.2129 - 2.193 0.235 - 448.8 2 2 0 0.0003 12 0 0 0 3.29E+08 1.06E+08 - - - 2.7083 0.9999 221125_WJC_METTL3_EV_vs_WT_F03.15172.15172.2 7.42E-07 13/22 R.QLVDTTVELANK[136.11].V sp|O75533|SF3B1_HUMAN 1 1337.7282 1.35 30727 15172 2 1337.728142 669.8714 Splicing factor 3B subunit 1 OS=Homo sapiens OX=9606 GN=SF3B1 PE=1 SV=3 4.37 2797.3 - 4.80E+06 - - - -0.0404 - 2.848 0.518 - 656.3 1 2 0 -0.0001 12 0 0 0 6.76E+07 5.01E+07 - - - 5.6208 0.9999 221125_WJC_METTL3_EV_vs_WT_F03.15173.15173.2 1.49E-05 20-Oct R.NLPLPPPPPPR[166.11].G "sp|P61978|HNRPK_HUMAN,tr|Q5T6W2|Q5T6W2_HUMAN" 2 1203.7003 1.55 30728 15173 2 1203.700036 602.8575 Heterogeneous nuclear ribonucleoprotein K OS=Homo sapiens OX=9606 GN=HNRNPK PE=1 SV=1 9.75 2797.3 - 3.97E+06 - - - -0.2592 - 1.816 0.523 - 303.9 1 2 0 -0.0003 11 0 0 0 2.41E+08 1.55E+08 - - - 4.5178 0.9998 221125_WJC_METTL3_EV_vs_WT_F03.15174.15174.3 0.0573 Nov-40 K.SFR[166.11]PGDIVLAK[136.11].V "sp|Q9Y3B2|EXOS1_HUMAN,tr|B1AMU3|B1AMU3_HUMAN,tr|B1AMU7|B1AMU7_HUMAN" 3 1219.7044 2.74 30729 15174 3 1219.703975 407.5754 Exosome complex component CSL4 OS=Homo sapiens OX=9606 GN=EXOSC1 PE=1 SV=1 8.46 2797.4 - 1.46E+06 - - - -0.3304 - 2.435 0.32 - 154 1 2 0 -0.0004 11 0 0 0 7.00E+07 2.55E+07 - - - 4.6358 0.9818 221125_WJC_METTL3_EV_vs_WT_F03.15175.15175.2 0.00371 14/22 L.IAQNLELNETIK.L "sp|P52732|KIF11_HUMAN,tr|A0A7I2V3A9|A0A7I2V3A9_HUMAN" 2 1384.7562 19.61 30730 15175 2 1384.759543 693.3854 Kinesin-like protein KIF11 OS=Homo sapiens OX=9606 GN=KIF11 PE=1 SV=2 4.53 2797.5 - 1.41E+06 - - - 2.4178 - 2.848 0.462 - 843.7 1 1 0 0.0033 12 0 0 0 1.08E+07 5.52E+05 - - - 5.2061 0.9987 221125_WJC_METTL3_EV_vs_WT_F03.15176.15176.2 0.0453 14-Aug K.ALEAVFGK.Y "sp|P38159|RBMX_HUMAN,tr|H3BT71|H3BT71_HUMAN,tr|H0Y6E7|H0Y6E7_HUMAN,tr|H3BR27|H3BR27_HUMAN,tr|H3BNC1|H3BNC1_HUMAN" 5 833.4647 1.84 30731 15176 2 833.463723 417.7396 "RNA-binding motif protein, X chromosome OS=Homo sapiens OX=9606 GN=RBMX PE=1 SV=3" 6.05 2797.6 - 937072 - - - -1.177 - 1.59 0.265 - 213.8 1 2 0 -0.001 8 0 0 0 8.33E+06 4.51E+06 - - - 2.3966 0.9999 221125_WJC_METTL3_EV_vs_WT_F03.15177.15177.3 2.53E-05 Nov-48 K.ILDSVGIEADDDR.L sp|P05387|RLA2_HUMAN 1 1416.6733 1.08 30732 15177 3 1416.674446 473.2317 60S acidic ribosomal protein P2 OS=Homo sapiens OX=9606 GN=RPLP2 PE=1 SV=1 3.71 2797.8 - 917395 - - - 0.8421 - 2.184 0.456 - 174.1 1 2 0 0.0012 13 0 0 0 4.85E+06 4.49E+06 - - - 5.7416 0.9994 221125_WJC_METTL3_EV_vs_WT_F03.15178.15178.3 0.0046 Sep-44 R.ELDATATVLANR[166.11].Q "sp|Q13948|CASP_HUMAN,sp|P39880|CUX1_HUMAN,tr|A0A2R8Y852|A0A2R8Y852_HUMAN,tr|A0A2R8YDI1|A0A2R8YDI1_HUMAN" 4 1282.6756 43.14 30733 15178 3 1282.677054 428.5658 Protein CASP OS=Homo sapiens OX=9606 GN=CUX1 PE=1 SV=2 4.37 2797.9 - 840287 - - - 1.0946 - 2.035 0.292 - 151.1 1 2 0 0.0014 12 0 0 0 2.47E+08 5.73E+06 - - - 3.7645 1 221125_WJC_METTL3_EV_vs_WT_F03.15180.15180.2 3.26E-09 19/34 T.AATAAAAAAAAYSDGYGR[166.11].V "sp|O43251|RFOX2_HUMAN,tr|B0QYV1|B0QYV1_HUMAN,tr|A0A0G2JRD1|A0A0G2JRD1_HUMAN,tr|A0A0G2JRA5|A0A0G2JRA5_HUMAN,tr|S4R3K7|S4R3K7_HUMAN" 5 1637.7673 2.09 30735 15180 2 1637.763573 819.8909 RNA binding protein fox-1 homolog 2 OS=Homo sapiens OX=9606 GN=RBFOX2 PE=1 SV=3 5.88 2798.1 - 390205 - - - -2.2866 - 4.076 0.687 - 1145.5 1 1 0 -0.0037 18 0 0 0 5.67E+06 2.72E+06 - - - 7.5685 1 221125_WJC_METTL3_EV_vs_WT_F03.15181.15181.2 0.000386 19/34 T.AATAAAAAAAAYSDGYGR.V "sp|O43251|RFOX2_HUMAN,tr|B0QYV1|B0QYV1_HUMAN,tr|A0A0G2JRD1|A0A0G2JRD1_HUMAN,tr|A0A0G2JRA5|A0A0G2JRA5_HUMAN,tr|S4R3K7|S4R3K7_HUMAN" 5 1627.759 2.09 30736 15181 2 1627.759156 814.8868 RNA binding protein fox-1 homolog 2 OS=Homo sapiens OX=9606 GN=RBFOX2 PE=1 SV=3 5.88 2798.3 - 364841 - - - 0.0663 - 3.255 0.603 - 721.7 1 1 0 0.0001 18 0 0 0 5.67E+06 2.72E+06 - - - 6.3963 0.9996 221125_WJC_METTL3_EV_vs_WT_F03.15184.15184.3 0.0773 Sep-36 R.LVNHFVEEFK[136.11].R "sp|P0DMV8|HS71A_HUMAN,sp|P0DMV9|HS71B_HUMAN,tr|V9GZ37|V9GZ37_HUMAN,tr|A0A0G2JIW1|A0A0G2JIW1_HUMAN" 4 1268.6645 0.14 30737 15184 3 1268.66303 423.8954 Heat shock 70 kDa protein 1A OS=Homo sapiens OX=9606 GN=HSPA1A PE=1 SV=1 5.4 2798.6 - 1.69E+07 - - - -1.1374 - 1.99 0.316 - 155.5 1 2 0 -0.0014 10 0 0 0 1.55E+09 1.13E+10 - - - 4.0723 0.9998 221125_WJC_METTL3_EV_vs_WT_F03.15185.15185.2 6.06E-05 22-Nov R.ELDATATVLANR[166.11].Q "sp|Q13948|CASP_HUMAN,sp|P39880|CUX1_HUMAN,tr|A0A2R8Y852|A0A2R8Y852_HUMAN,tr|A0A2R8YDI1|A0A2R8YDI1_HUMAN" 4 1282.6756 2.89 30738 15185 2 1282.675084 642.3451 Protein CASP OS=Homo sapiens OX=9606 GN=CUX1 PE=1 SV=2 4.37 2798.7 - 8.30E+06 - - - -0.4413 - 2.353 0.419 - 554.1 1 2 0 -0.0006 12 0 0 0 3.05E+08 1.05E+08 - - - 4.387 0.9983 221125_WJC_METTL3_EV_vs_WT_F03.15186.15186.2 0.69 16-Sep K.SISLEPLQK.E sp|Q8N0T1|RBIS_HUMAN 1 1013.5757 4.11 30739 15186 2 1013.575926 507.7951 Ribosomal biogenesis factor OS=Homo sapiens OX=9606 GN=RBIS PE=1 SV=4 5.72 2798.7 - 1.12E+07 - - - 0.2121 - 1.486 0.235 - 188.5 1 2 0 0.0002 9 0 0 0 4.04E+08 9.81E+07 - - - 1.9225 0.9995 221125_WJC_METTL3_EV_vs_WT_F03.15187.15187.2 0.163 16-Sep K.LSEQELQFR.R "sp|Q16891|MIC60_HUMAN,tr|B9A067|B9A067_HUMAN,tr|C9J406|C9J406_HUMAN,tr|H7C463|H7C463_HUMAN" 4 1148.5826 1.32 30740 15187 2 1148.580757 575.2986 MICOS complex subunit MIC60 OS=Homo sapiens OX=9606 GN=IMMT PE=1 SV=1 4.53 2798.8 - 9.54E+06 - - - -1.5941 - 2.062 0.328 - 365.5 1 2 0 -0.0018 9 0 0 0 9.11E+08 6.88E+08 - - - 3.5567 0.9998 221125_WJC_METTL3_EV_vs_WT_F03.15188.15188.2 0.00103 16-Sep R.EAQLLSLSK.E "sp|P82094|TMF1_HUMAN,tr|F8WF45|F8WF45_HUMAN,tr|A0A2R8Y7M0|A0A2R8Y7M0_HUMAN" 3 987.5601 1.61 30741 15188 2 987.55966 494.7873 TATA element modulatory factor OS=Homo sapiens OX=9606 GN=TMF1 PE=1 SV=2 6.1 2798.8 - 8.62E+06 - - - -0.4061 - 1.752 0.442 - 325 1 2 0 -0.0004 9 0 0 0 1.30E+08 8.07E+07 - - - 3.9278 0.9997 221125_WJC_METTL3_EV_vs_WT_F03.15189.15189.2 0.00808 16-Sep K.LSEQELQFR[166.11].R "sp|Q16891|MIC60_HUMAN,tr|B9A067|B9A067_HUMAN,tr|C9J406|C9J406_HUMAN,tr|H7C463|H7C463_HUMAN" 4 1158.5909 1.32 30742 15189 2 1158.590427 580.3027 MICOS complex subunit MIC60 OS=Homo sapiens OX=9606 GN=IMMT PE=1 SV=1 4.53 2798.8 - 7.93E+06 - - - -0.372 - 2.067 0.354 - 297.4 1 2 0 -0.0004 9 0 0 0 9.11E+08 6.89E+08 - - - 3.7562 0.997 221125_WJC_METTL3_EV_vs_WT_F03.15191.15191.2 0.000107 18-Aug K.FYSVNVDYSK[136.11].L sp|O00483|NDUA4_HUMAN 1 1228.5856 12.24 30744 15191 2 1228.590564 615.3001 Cytochrome c oxidase subunit NDUFA4 OS=Homo sapiens OX=9606 GN=NDUFA4 PE=1 SV=1 5.83 2798.9 - 2.63E+06 - - - 4.0779 - 1.397 0.491 - 140.7 1 2 0 0.005 10 0 0 0 2.54E+08 2.08E+07 - - - 3.5992 0.9997 221125_WJC_METTL3_EV_vs_WT_F03.15193.15193.2 0.00199 18-Sep K.STLSNQLLGR.K "sp|O75616|ERAL1_HUMAN,tr|J3QSB2|J3QSB2_HUMAN,tr|J3QRV9|J3QRV9_HUMAN,tr|J3QT61|J3QT61_HUMAN" 4 1087.5986 0.2 30746 15193 2 1087.599337 544.8066 "GTPase Era, mitochondrial OS=Homo sapiens OX=9606 GN=ERAL1 PE=1 SV=2" 9.47 2799.1 - 1.43E+06 - - - 0.7034 - 1.955 0.413 - 236.7 1 2 0 0.0008 10 0 0 0 1.50E+07 7.40E+07 - - - 3.9624 0.9998 221125_WJC_METTL3_EV_vs_WT_F03.15195.15195.2 0.00028 18-Oct K.EVFEDAAEIR.L "sp|P19338|NUCL_HUMAN,tr|A0A7I2V506|A0A7I2V506_HUMAN,tr|A0A7I2V2U7|A0A7I2V2U7_HUMAN,tr|A0A7I2V3F3|A0A7I2V3F3_HUMAN,tr|A0A7I2V428|A0A7I2V428_HUMAN,tr|A0A7I2V349|A0A7I2V349_HUMAN,tr|H7BY16|H7BY16_HUMAN,tr|A0A7I2V5M5|A0A7I2V5M5_HUMAN,tr|C9JLB1|C9JLB1_HUMAN" 9 1177.5615 3.9 30748 15195 2 1177.560779 589.788 Nucleolin OS=Homo sapiens OX=9606 GN=NCL PE=1 SV=3 4 2799.4 - 989299 - - - -0.6276 - 2.106 0.447 - 360.8 1 2 0 -0.0007 10 0 0 0 1.03E+08 2.64E+07 - - - 4.4212 0.9999 221125_WJC_METTL3_EV_vs_WT_F03.15196.15196.3 3.19E-05 Nov-48 K.ILDSVGIEADDDR[166.11].L sp|P05387|RLA2_HUMAN 1 1426.6815 3.16 30749 15196 3 1426.680719 476.5678 60S acidic ribosomal protein P2 OS=Homo sapiens OX=9606 GN=RPLP2 PE=1 SV=1 3.71 2799.5 - 741535 - - - -0.5635 - 2.095 0.446 - 136 1 2 0 -0.0008 13 0 0 0 1.79E+07 5.67E+06 - - - 5.5174 0.9999 221125_WJC_METTL3_EV_vs_WT_F03.15198.15198.2 3.88E-08 16/26 K.TPAFAESVTEGDVR[166.11].W "sp|P36957|ODO2_HUMAN,tr|G3V3F0|G3V3F0_HUMAN,tr|Q86SW4|Q86SW4_HUMAN,tr|G3V5M3|G3V5M3_HUMAN,tr|H0YJF9|H0YJF9_HUMAN" 5 1487.7132 1.19 30751 15198 2 1487.713607 744.8639 "Dihydrolipoyllysine-residue succinyltransferase component of 2-oxoglutarate dehydrogenase complex, mitochondrial OS=Homo sapiens OX=9606 GN=DLST PE=1 SV=4" 4.14 2799.8 - 573414 - - - 0.3018 - 3.294 0.44 - 868.1 1 2 0 0.0004 14 0 0 0 4.06E+07 3.41E+07 - - - 5.2822 0.9998 221125_WJC_METTL3_EV_vs_WT_F03.15199.15199.2 0.00865 26-Dec R.VLHVSENPVPLTVR[166.11].V sp|Q8N1G4|LRC47_HUMAN 1 1568.8914 0.77 30752 15199 2 1568.890942 785.453 Leucine-rich repeat-containing protein 47 OS=Homo sapiens OX=9606 GN=LRRC47 PE=1 SV=1 6.72 2799.9 - 291131 - - - -0.29 - 2.033 0.459 - 364.9 1 2 0 -0.0005 14 0 0 0 1.05E+06 1.38E+06 - - - 4.2115 0.9997 221125_WJC_METTL3_EV_vs_WT_F03.15201.15201.2 0.00113 14-Aug K.QWGWTQGR[166.11].W "sp|P18621|RL17_HUMAN,tr|A0A087WWH0|A0A087WWH0_HUMAN,tr|J3QS96|J3QS96_HUMAN,tr|J3QLC8|J3QLC8_HUMAN,tr|J3QQT2|J3QQT2_HUMAN,tr|A0A087WY81|A0A087WY81_HUMAN,tr|A0A0A0MRF8|A0A0A0MRF8_HUMAN,tr|J3KRB3|J3KRB3_HUMAN,tr|J3KRX5|J3KRX5_HUMAN,tr|A0A087WXM6|A0A087WXM6_HUMAN,tr|A0A0A6YYL6|A0A0A6YYL6_HUMAN" 11 1027.4863 0.95 30753 15201 2 1027.485968 514.7504 60S ribosomal protein L17 OS=Homo sapiens OX=9606 GN=RPL17 PE=1 SV=3 9.75 2800.1 - 1.47E+07 - - - -0.3552 - 1.514 0.422 - 327.9 1 2 0 -0.0004 8 0 0 0 2.58E+08 2.71E+08 - - - 3.4087 0.9999 221125_WJC_METTL3_EV_vs_WT_F03.15202.15202.2 1.64E-05 20-Oct R.SFDDPIVQTER[166.11].L "sp|O95757|HS74L_HUMAN,tr|D6RJ96|D6RJ96_HUMAN,tr|E9PDE8|E9PDE8_HUMAN" 3 1315.6284 0.13 30754 15202 2 1315.626909 658.8215 Heat shock 70 kDa protein 4L OS=Homo sapiens OX=9606 GN=HSPA4L PE=1 SV=3 4.03 2800.2 - 6.42E+06 - - - -1.1067 - 2.207 0.576 - 241.9 1 2 0 -0.0015 11 0 0 0 1.69E+07 1.28E+08 - - - 5.4364 1 221125_WJC_METTL3_EV_vs_WT_F03.15203.15203.2 3.87E-09 13/18 R.LVNHFVEEFK[136.11].R "sp|P0DMV8|HS71A_HUMAN,sp|P0DMV9|HS71B_HUMAN,tr|V9GZ37|V9GZ37_HUMAN,tr|A0A0G2JIW1|A0A0G2JIW1_HUMAN" 4 1268.6645 0.16 30755 15203 2 1268.664377 635.3395 Heat shock 70 kDa protein 1A OS=Homo sapiens OX=9606 GN=HSPA1A PE=1 SV=1 5.4 2800.2 - 1.73E+07 - - - -0.0757 - 2.815 0.631 - 811.7 1 2 0 -0.0001 10 0 0 0 7.22E+08 4.52E+09 - - - 6.5904 0.9994 221125_WJC_METTL3_EV_vs_WT_F03.15204.15204.2 0.0261 16-Sep R.EAQLLSLSK[136.11].E "sp|P82094|TMF1_HUMAN,tr|F8WF45|F8WF45_HUMAN,tr|A0A2R8Y7M0|A0A2R8Y7M0_HUMAN" 3 995.5743 1.61 30756 15204 2 995.5726 498.7944 TATA element modulatory factor OS=Homo sapiens OX=9606 GN=TMF1 PE=1 SV=2 6.1 2800.3 - 7.05E+06 - - - -1.6684 - 1.659 0.384 - 431.2 1 2 0 -0.0017 9 0 0 0 1.30E+08 8.07E+07 - - - 3.3412 1 221125_WJC_METTL3_EV_vs_WT_F03.15208.15208.2 4.39E-08 18-Dec R.LVNHFVEEFK.R "sp|P0DMV8|HS71A_HUMAN,sp|P0DMV9|HS71B_HUMAN,tr|V9GZ37|V9GZ37_HUMAN,tr|A0A0G2JIW1|A0A0G2JIW1_HUMAN" 4 1260.6503 0.16 30760 15208 2 1260.649325 631.3324 Heat shock 70 kDa protein 1A OS=Homo sapiens OX=9606 GN=HSPA1A PE=1 SV=1 5.4 2800.5 - 2.11E+06 - - - -0.752 - 2.685 0.595 - 644.2 1 2 0 -0.0009 10 0 0 0 7.21E+08 4.52E+09 - - - 6.1923 0.9988 221125_WJC_METTL3_EV_vs_WT_F03.15209.15209.2 0.00758 14/28 R.GPLEPSEPAVVAAAR.V "sp|P29372|3MG_HUMAN,tr|A2IDA3|A2IDA3_HUMAN" 2 1462.778 1.05 30761 15209 2 1462.783166 732.3963 DNA-3-methyladenine glycosylase OS=Homo sapiens OX=9606 GN=MPG PE=1 SV=3 4.53 2800.6 - 1.61E+06 - - - 3.5364 - 2.42 0.416 - 435.8 1 2 0 0.0052 15 0 0 0 2.55E+07 2.42E+07 - - - 4.2847 1 221125_WJC_METTL3_EV_vs_WT_F03.15211.15211.2 1.11E-07 14/24 R.VGIQQGLLSQSTR[166.11].T "sp|Q9BY77|PDIP3_HUMAN,tr|F6VRR5|F6VRR5_HUMAN,tr|F8WCX5|F8WCX5_HUMAN,tr|Q6R954|Q6R954_HUMAN,tr|Q8WUT1|Q8WUT1_HUMAN,tr|F8WEE2|F8WEE2_HUMAN" 6 1395.7709 1.29 30763 15211 2 1395.773343 698.8927 Polymerase delta-interacting protein 3 OS=Homo sapiens OX=9606 GN=POLDIP3 PE=1 SV=2 9.72 2800.8 - 1.50E+06 - - - 1.7166 - 3.069 0.539 - 732.7 1 2 0 0.0024 13 0 0 0 2.67E+09 2.07E+09 - - - 5.8993 1 221125_WJC_METTL3_EV_vs_WT_F03.15213.15213.3 1.16E-05 20/48 K.TVTSATIVYHLAR[166.11].Q sp|Q92900|RENT1_HUMAN 1 1440.7964 0.98 30765 15213 3 1440.795264 481.2728 Regulator of nonsense transcripts 1 OS=Homo sapiens OX=9606 GN=UPF1 PE=1 SV=2 8.44 2801 - 1.14E+06 - - - -0.8121 - 3.161 0.507 - 488.9 1 2 0 -0.0012 13 0 0 0 6.90E+07 7.05E+07 - - - 7.3126 1 221125_WJC_METTL3_EV_vs_WT_F03.15214.15214.3 4.04E-05 18/48 K.TVTSATIVYHLAR.Q sp|Q92900|RENT1_HUMAN 1 1430.7882 0.98 30766 15214 3 1430.787341 477.9367 Regulator of nonsense transcripts 1 OS=Homo sapiens OX=9606 GN=UPF1 PE=1 SV=2 8.44 2801.2 - 1.02E+06 - - - -0.5752 - 2.784 0.522 - 308.3 1 2 0 -0.0008 13 0 0 0 6.90E+07 7.05E+07 - - - 7.1356 0.9995 221125_WJC_METTL3_EV_vs_WT_F03.15215.15215.2 7.49E-05 14/26 R.GTQLLSSGSDGLVK[136.11].L "sp|Q12788|TBL3_HUMAN,tr|J3KNP2|J3KNP2_HUMAN,tr|A0A087WYP7|A0A087WYP7_HUMAN" 3 1368.734 1.66 30767 15215 2 1368.73085 685.3743 Transducin beta-like protein 3 OS=Homo sapiens OX=9606 GN=TBL3 PE=1 SV=2 5.84 2801.3 - 749487 - - - -2.308 - 2.456 0.383 - 709.5 1 2 0 -0.0032 14 0 0 0 2.80E+07 1.69E+07 - - - 4.1237 0.9317 221125_WJC_METTL3_EV_vs_WT_F03.15216.15216.3 0.895 Oct-36 K.NLQMWEEMK[136.11]K[136.11].G "sp|P07814|SYEP_HUMAN,tr|V9GYZ6|V9GYZ6_HUMAN" 2 1351.6599 1.35 30768 15216 3 1351.658178 451.5606 Bifunctional glutamate\proline--tRNA ligase OS=Homo sapiens OX=9606 GN=EPRS1 PE=1 SV=5 6.14 2801.4 - 511967 - - - -1.2947 - 1.329 0.124 - 136.8 1 2 0 -0.0018 10 0 0 0 9.39E+06 6.98E+06 - - - 0.7526 0.9996 221125_WJC_METTL3_EV_vs_WT_F03.15217.15217.2 5.44E-06 16/26 R.GTQLLSSGSDGLVK.L "sp|Q12788|TBL3_HUMAN,tr|J3KNP2|J3KNP2_HUMAN,tr|A0A087WYP7|A0A087WYP7_HUMAN" 3 1360.7198 1.66 30769 15217 2 1360.715774 681.3672 Transducin beta-like protein 3 OS=Homo sapiens OX=9606 GN=TBL3 PE=1 SV=2 5.84 2801.6 - 480315 - - - -2.9653 - 3 0.528 - 967 1 2 0 -0.004 14 0 0 0 2.80E+07 1.69E+07 - - - 5.6965 1 221125_WJC_METTL3_EV_vs_WT_F03.15220.15220.3 0.000615 Oct-36 R.LVNHFVEEFK.R "sp|P0DMV8|HS71A_HUMAN,sp|P0DMV9|HS71B_HUMAN,tr|V9GZ37|V9GZ37_HUMAN,tr|A0A0G2JIW1|A0A0G2JIW1_HUMAN" 4 1260.6503 0.14 30770 15220 3 1260.649763 421.224 Heat shock 70 kDa protein 1A OS=Homo sapiens OX=9606 GN=HSPA1A PE=1 SV=1 5.4 2801.9 - 2.25E+07 - - - -0.4046 - 2.016 0.481 - 204.4 1 2 0 -0.0005 10 0 0 0 1.55E+09 1.13E+10 - - - 5.9501 0.9958 221125_WJC_METTL3_EV_vs_WT_F03.15221.15221.2 0.0852 14-Jul K.QWGWTQGR.W "sp|P18621|RL17_HUMAN,tr|A0A087WWH0|A0A087WWH0_HUMAN,tr|J3QS96|J3QS96_HUMAN,tr|J3QLC8|J3QLC8_HUMAN,tr|J3QQT2|J3QQT2_HUMAN,tr|A0A087WY81|A0A087WY81_HUMAN,tr|A0A0A0MRF8|A0A0A0MRF8_HUMAN,tr|J3KRB3|J3KRB3_HUMAN,tr|J3KRX5|J3KRX5_HUMAN,tr|A0A087WXM6|A0A087WXM6_HUMAN,tr|A0A0A6YYL6|A0A0A6YYL6_HUMAN" 11 1017.4781 0.95 30771 15221 2 1017.478384 509.7463 60S ribosomal protein L17 OS=Homo sapiens OX=9606 GN=RPL17 PE=1 SV=3 9.75 2802 - 1.52E+07 - - - 0.3155 - 1.417 0.157 - 262.8 1 2 0 0.0003 8 0 0 0 2.57E+08 2.70E+08 - - - 1.2517 0.9995 221125_WJC_METTL3_EV_vs_WT_F03.15222.15222.2 0.05 20-Dec K.GLALSNSDVIR.Q "sp|Q9Y5K5|UCHL5_HUMAN,tr|Q5LJA9|Q5LJA9_HUMAN,tr|H0Y6Y4|H0Y6Y4_HUMAN,tr|Q5LJB0|Q5LJB0_HUMAN,tr|Q5LJA5|Q5LJA5_HUMAN" 5 1143.6248 2.23 30772 15222 2 1143.625069 572.8197 Ubiquitin carboxyl-terminal hydrolase isozyme L5 OS=Homo sapiens OX=9606 GN=UCHL5 PE=1 SV=3 5.84 2802 - 1.20E+07 - - - 0.2466 - 2.05 0.281 - 665.6 1 2 0 0.0003 11 0 0 0 1.59E+08 7.14E+07 - - - 3.0583 0.9995 221125_WJC_METTL3_EV_vs_WT_F03.15226.15226.2 7.87E-05 14-Sep R.QMFGQFGK[136.11].L "sp|O43251|RFOX2_HUMAN,sp|Q9NWB1|RFOX1_HUMAN,sp|A6NFN3|RFOX3_HUMAN,tr|A0A6Q8PGE0|A0A6Q8PGE0_HUMAN,tr|A0A6Q8PH77|A0A6Q8PH77_HUMAN,tr|A0A286YEU2|A0A286YEU2_HUMAN,tr|A0A087X2B1|A0A087X2B1_HUMAN,tr|F8VR27|F8VR27_HUMAN,tr|B7Z1U7|B7Z1U7_HUMAN,tr|B0QYV1|B0QYV1_HUMAN,tr|A0A6Q8PHA3|A0A6Q8PHA3_HUMAN,tr|A0A3B3ITL7|A0A3B3ITL7_HUMAN,tr|F8VZY7|F8VZY7_HUMAN,tr|B0QYY4|B0QYY4_HUMAN,tr|J3KNW3|J3KNW3_HUMAN,tr|F8VZG9|F8VZG9_HUMAN,tr|J3QRF4|J3QRF4_HUMAN,tr|A0A6Q8PFM4|A0A6Q8PFM4_HUMAN,tr|S4R469|S4R469_HUMAN,tr|A0A804HKG7|A0A804HKG7_HUMAN,tr|A0A0G2JRA5|A0A0G2JRA5_HUMAN,tr|A0A804HJM2|A0A804HJM2_HUMAN,tr|J3QQZ2|J3QQZ2_HUMAN,tr|I3L1D4|I3L1D4_HUMAN,tr|B0QYY7|B0QYY7_HUMAN,tr|A0A0G2JSB3|A0A0G2JSB3_HUMAN" 26 949.4571 1.04 30776 15226 2 949.455003 475.7358 RNA binding protein fox-1 homolog 2 OS=Homo sapiens OX=9606 GN=RBFOX2 PE=1 SV=3 8.75 2802.2 - 2.24E+06 - - - -2.2329 - 1.539 0.496 - 273 1 2 0 -0.0021 8 0 0 0 3.83E+08 3.68E+08 - - - 4.0041 0.9132 221125_WJC_METTL3_EV_vs_WT_F03.15227.15227.2 0.0241 18-Oct Y.SATFPLSVQK[136.11].F sp|P26196|DDX6_HUMAN 1 1084.6008 0.84 30777 15227 2 1084.597144 543.3077 Probable ATP-dependent RNA helicase DDX6 OS=Homo sapiens OX=9606 GN=DDX6 PE=1 SV=2 8.47 2802.3 - 1.70E+06 - - - -3.38 - 1.841 0.402 - 419.3 1 1 0 -0.0037 10 0 0 0 2.00E+07 2.39E+07 - - - 3.7126 1 221125_WJC_METTL3_EV_vs_WT_F03.15228.15228.2 0.0512 18/26 K.TPAFAESVTEGDVR.W "sp|P36957|ODO2_HUMAN,tr|G3V3F0|G3V3F0_HUMAN,tr|Q86SW4|Q86SW4_HUMAN,tr|G3V5M3|G3V5M3_HUMAN,tr|H0YJF9|H0YJF9_HUMAN" 5 1477.7049 1.18 30778 15228 2 1477.703988 739.8597 "Dihydrolipoyllysine-residue succinyltransferase component of 2-oxoglutarate dehydrogenase complex, mitochondrial OS=Homo sapiens OX=9606 GN=DLST PE=1 SV=4" 4.14 2802.4 - 1.57E+06 - - - -0.6091 - 3.541 0.59 - 1190.2 1 2 0 -0.0009 14 0 0 0 4.06E+07 3.43E+07 - - - 6.5714 0.9971 221125_WJC_METTL3_EV_vs_WT_F03.15230.15230.2 0.069 16-Sep K.QEGLESVLK.L sp|P14923|PLAK_HUMAN 1 1001.5393 166.6 30780 15230 2 1001.536357 501.7769 Junction plakoglobin OS=Homo sapiens OX=9606 GN=JUP PE=1 SV=3 4.53 2802.7 - 815210 - - - -2.9644 - 1.816 0.266 - 246.9 1 2 0 -0.003 9 0 0 0 2.06E+08 1.23E+06 - - - 2.7308 0.9999 221125_WJC_METTL3_EV_vs_WT_F03.15234.15234.3 0.0365 18/40 R.NLPLPPPPPPR.G "sp|P61978|HNRPK_HUMAN,tr|Q5T6W2|Q5T6W2_HUMAN" 2 1193.6921 3.33 30783 15234 3 1193.69281 398.9046 Heterogeneous nuclear ribonucleoprotein K OS=Homo sapiens OX=9606 GN=HNRNPK PE=1 SV=1 9.75 2803.2 - 1.64E+06 - - - 0.6132 - 3.329 0.334 - 604.4 1 2 0 0.0007 11 0 0 0 3.53E+07 1.06E+07 - - - 5.6802 0.9999 221125_WJC_METTL3_EV_vs_WT_F03.15236.15236.3 5.38E-06 16/48 R.VGIQQGLLSQSTR.T "sp|Q9BY77|PDIP3_HUMAN,tr|F6VRR5|F6VRR5_HUMAN,tr|F8WCX5|F8WCX5_HUMAN,tr|Q6R954|Q6R954_HUMAN,tr|Q8WUT1|Q8WUT1_HUMAN,tr|F8WEE2|F8WEE2_HUMAN" 6 1385.7627 1.33 30784 15236 3 1385.761249 462.9282 Polymerase delta-interacting protein 3 OS=Homo sapiens OX=9606 GN=POLDIP3 PE=1 SV=2 9.72 2803.4 - 2.21E+06 - - - -1.0305 - 2.646 0.417 - 373.8 1 2 0 -0.0014 13 0 0 0 2.36E+08 1.77E+08 - - - 5.827 1 221125_WJC_METTL3_EV_vs_WT_F03.15237.15237.3 0.00374 13/40 K.LFNEHIEALTK[136.11].K "sp|O14776|TCRG1_HUMAN,tr|A0A7P0T8N8|A0A7P0T8N8_HUMAN,tr|G3V220|G3V220_HUMAN" 3 1321.7122 0.67 30785 15237 3 1321.71246 441.578 Transcription elongation regulator 1 OS=Homo sapiens OX=9606 GN=TCERG1 PE=1 SV=2 5.4 2803.5 - 2.75E+06 - - - 0.233 - 2.765 0.434 - 191.8 1 2 0 0.0003 11 0 0 0 3.13E+07 4.66E+07 - - - 6.2678 0.9999 221125_WJC_METTL3_EV_vs_WT_F03.15238.15238.2 0.0154 22-Nov K.YQEVTNNLEFAK.E "sp|Q14444|CAPR1_HUMAN,tr|G3V153|G3V153_HUMAN,tr|E9PLA9|E9PLA9_HUMAN" 3 1454.7042 0.94 30786 15238 2 1454.703189 728.3594 Caprin-1 OS=Homo sapiens OX=9606 GN=CAPRIN1 PE=1 SV=2 4.53 2803.5 - 4.38E+06 - - - -0.6668 - 2.223 0.501 - 279.3 1 2 0 -0.001 12 0 0 0 6.15E+08 6.52E+08 - - - 4.843 0.999 221125_WJC_METTL3_EV_vs_WT_F03.15239.15239.2 0.000114 16-Aug K.EMEQLVLDK[136.11].K sp|Q96A49|SYAP1_HUMAN 1 1111.5675 1.29 30787 15239 2 1111.564226 556.791 Synapse-associated protein 1 OS=Homo sapiens OX=9606 GN=SYAP1 PE=1 SV=1 4.14 2803.6 - 3.04E+06 - - - -2.9103 - 1.728 0.43 - 245.2 1 2 0 -0.0032 9 0 0 0 1.97E+08 1.53E+08 - - - 3.7984 0.9998 221125_WJC_METTL3_EV_vs_WT_F03.15241.15241.3 3.87E-06 Nov-40 R.K[136.11]LVIIEGDLER[166.11].T "sp|P06753|TPM3_HUMAN,tr|A0A2R2Y2Q3|A0A2R2Y2Q3_HUMAN,tr|A0A087WWU8|A0A087WWU8_HUMAN,tr|J3KN67|J3KN67_HUMAN,tr|A0A494C0P6|A0A494C0P6_HUMAN" 5 1301.7674 0.93 30789 15241 3 1301.76419 434.9297 Tropomyosin alpha-3 chain OS=Homo sapiens OX=9606 GN=TPM3 PE=1 SV=2 4.68 2803.8 - 680702 - - - -2.4444 - 2.526 0.396 - 281.8 1 2 0 -0.0032 11 0 0 0 6.92E+07 7.44E+07 - - - 5.5865 0.9996 221125_WJC_METTL3_EV_vs_WT_F03.15246.15246.2 0.00269 20-Nov K.TIALNGVEDVR[166.11].T "sp|Q3ZCQ8|TIM50_HUMAN,tr|M0R0C3|M0R0C3_HUMAN,tr|M0R2F8|M0R2F8_HUMAN" 3 1195.6436 0.07 30792 15246 2 1195.642837 598.8291 Mitochondrial import inner membrane translocase subunit TIM50 OS=Homo sapiens OX=9606 GN=TIMM50 PE=1 SV=2 4.37 2804.2 - 6.49E+06 - - - -0.6557 - 2.023 0.305 - 366.3 1 2 0 -0.0008 11 0 0 0 1.09E+07 1.45E+08 - - - 3.1995 0.9999 221125_WJC_METTL3_EV_vs_WT_F03.15247.15247.2 0.000355 14/22 K.ILLNAGAEINSR[166.11].T "sp|O75179|ANR17_HUMAN,sp|Q8IWZ3|ANKH1_HUMAN,tr|E9PDP5|E9PDP5_HUMAN,tr|H0YM23|H0YM23_HUMAN,tr|H3BLS9|H3BLS9_HUMAN,tr|H0YLQ3|H0YLQ3_HUMAN,tr|H7C2F5|H7C2F5_HUMAN" 7 1279.7124 0.001 30793 15247 2 1279.711174 640.8635 Ankyrin repeat domain-containing protein 17 OS=Homo sapiens OX=9606 GN=ANKRD17 PE=1 SV=3 6 2804.3 - 2.85E+06 - - - -0.9346 - 2.678 0.479 - 748.2 1 2 0 -0.0012 12 0 0 0 0.00E+00 6.34E+07 - - - 5.1704 1 221125_WJC_METTL3_EV_vs_WT_F03.15248.15248.2 6.05E-09 14/22 K.QYNGVPLDGR[166.11]PM.N "sp|Q86V81|THOC4_HUMAN,tr|E9PB61|E9PB61_HUMAN" 2 1355.6531 0.63 30794 15248 2 1355.650431 678.8338 THO complex subunit 4 OS=Homo sapiens OX=9606 GN=ALYREF PE=1 SV=3 5.84 2804.4 - 2.26E+06 - - - -1.9983 - 2.411 0.617 - 519.9 1 1 0 -0.0027 12 0 0 0 4.12E+07 6.54E+07 - - - 5.9129 0.9994 221125_WJC_METTL3_EV_vs_WT_F03.15251.15251.2 6.26E-05 14-Oct K.HQLFLQLK[136.11].K "sp|Q13227|GPS2_HUMAN,tr|I3L3Y9|I3L3Y9_HUMAN,tr|I3L4X7|I3L4X7_HUMAN" 3 1033.6164 2.66 30797 15251 2 1033.61528 517.8155 G protein pathway suppressor 2 OS=Homo sapiens OX=9606 GN=GPS2 PE=1 SV=3 8.76 2804.8 - 1.01E+06 - - - -1.0845 - 2.084 0.254 - 273.6 1 2 0 -0.0011 8 0 0 0 4.52E+07 1.70E+07 - - - 3.1313 0.9989 221125_WJC_METTL3_EV_vs_WT_F03.15254.15254.2 4.99E-05 20-Nov R.TAAENEFVTLK.K "sp|P48668|K2C6C_HUMAN,sp|P12035|K2C3_HUMAN,sp|P04259|K2C6B_HUMAN,sp|P02538|K2C6A_HUMAN" 4 1221.6241 83.51 30798 15254 2 1221.619404 611.8193 "Keratin, type II cytoskeletal 6C OS=Homo sapiens OX=9606 GN=KRT6C PE=1 SV=3" 4.53 2805.2 - 2.11E+07 - - - -3.8588 - 2.172 0.492 - 389 1 2 0 -0.0047 11 0 0 0 4.92E+09 5.89E+07 - - - 4.7717 0.9987 221125_WJC_METTL3_EV_vs_WT_F03.15255.15255.2 1.40E-05 16-Sep R.GDFC[160.03]IQVGR[166.11].N "sp|O60361|NDK8_HUMAN,sp|P15531|NDKA_HUMAN,sp|P22392|NDKB_HUMAN,tr|Q32Q12|Q32Q12_HUMAN,tr|Q32Q12|Q32Q12_HUMAN,tr|J3KPD9|J3KPD9_HUMAN,tr|E7ERL0|E7ERL0_HUMAN" 7 1060.4999 1.27 30799 15255 2 1060.495954 531.2572 Putative nucleoside diphosphate kinase OS=Homo sapiens OX=9606 GN=NME2P1 PE=5 SV=1 5.83 2805.3 - 1.33E+07 - - - -3.7529 - 1.863 0.48 - 316.9 1 2 0 -0.004 9 0 0 0 8.04E+08 6.31E+08 - - - 4.3851 0.9998 221125_WJC_METTL3_EV_vs_WT_F03.15257.15257.2 9.18E-05 22-Dec K.DAGLIEANGELK.V "sp|Q14186|TFDP1_HUMAN,tr|F5H452|F5H452_HUMAN,tr|Q5JSB6|Q5JSB6_HUMAN,tr|Q5JSB5|Q5JSB5_HUMAN" 4 1228.6299 1.87 30801 15257 2 1228.631476 615.3222 Transcription factor Dp-1 OS=Homo sapiens OX=9606 GN=TFDP1 PE=1 SV=1 4.14 2805.4 - 1.85E+06 - - - 1.2567 - 2.362 0.486 - 454.6 1 2 0 0.0015 12 0 0 0 6.19E+07 3.31E+07 - - - 4.8916 0.7884 221125_WJC_METTL3_EV_vs_WT_F03.15259.15259.3 2.11 Sep-44 K.YQEVTNNLEFAK[136.11].E "sp|Q14444|CAPR1_HUMAN,tr|G3V153|G3V153_HUMAN,tr|E9PLA9|E9PLA9_HUMAN" 3 1462.7184 1.02 30803 15259 3 1462.71403 488.5801 Caprin-1 OS=Homo sapiens OX=9606 GN=CAPRIN1 PE=1 SV=2 4.53 2805.6 - 796531 - - - -2.9596 - 1.628 0.07 - 114.7 1 2 0 -0.0043 12 0 0 0 1.61E+07 1.59E+07 - - - 0.6701 0.9997 221125_WJC_METTL3_EV_vs_WT_F03.15261.15261.2 0.00018 16-Aug K.EMEQLVLDK.K sp|Q96A49|SYAP1_HUMAN 1 1103.5533 1.29 30804 15261 2 1103.55208 552.7839 Synapse-associated protein 1 OS=Homo sapiens OX=9606 GN=SYAP1 PE=1 SV=1 4.14 2805.9 - 9.12E+06 - - - -1.0702 - 1.752 0.42 - 342.5 1 2 0 -0.0012 9 0 0 0 2.03E+08 1.58E+08 - - - 3.7651 0.9999 221125_WJC_METTL3_EV_vs_WT_F03.15263.15263.3 0.0484 13/48 R.VGIQQGLLSQSTR[166.11].T "sp|Q9BY77|PDIP3_HUMAN,tr|F6VRR5|F6VRR5_HUMAN,tr|F8WCX5|F8WCX5_HUMAN,tr|Q6R954|Q6R954_HUMAN,tr|Q8WUT1|Q8WUT1_HUMAN,tr|F8WEE2|F8WEE2_HUMAN" 6 1395.7709 1.34 30805 15263 3 1395.768634 466.2643 Polymerase delta-interacting protein 3 OS=Homo sapiens OX=9606 GN=POLDIP3 PE=1 SV=2 9.72 2806.1 - 1.02E+07 - - - -1.6571 - 2.848 0.365 - 195.5 1 2 0 -0.0023 13 0 0 0 2.35E+08 1.76E+08 - - - 5.4464 1 221125_WJC_METTL3_EV_vs_WT_F03.15266.15266.2 2.54E-07 16-Dec L.VNHFVEEFK[136.11].R "sp|P0DMV8|HS71A_HUMAN,sp|P0DMV9|HS71B_HUMAN,tr|V9GZ37|V9GZ37_HUMAN,tr|A0A0G2JIW1|A0A0G2JIW1_HUMAN" 4 1155.5804 0.1 30808 15266 2 1155.578861 578.7975 Heat shock 70 kDa protein 1A OS=Homo sapiens OX=9606 GN=HSPA1A PE=1 SV=1 5.4 2806.3 - 3.10E+07 - - - -1.3396 - 2.494 0.549 - 730.7 1 1 0 -0.0015 9 0 0 0 6.50E+07 6.48E+08 - - - 5.7394 1 221125_WJC_METTL3_EV_vs_WT_F03.15271.15271.3 2.76E-07 18/56 K.GVTIVK[136.11]PIVYGNVAR[166.11].Y "sp|O95619|YETS4_HUMAN,tr|F8W1B9|F8W1B9_HUMAN,tr|F8W0J4|F8W0J4_HUMAN" 3 1602.9576 0.98 30811 15271 3 1602.954339 535.3265 YEATS domain-containing protein 4 OS=Homo sapiens OX=9606 GN=YEATS4 PE=1 SV=1 9.99 2806.8 - 2.11E+06 - - - -2.0543 - 2.906 0.578 - 332.6 1 2 0 -0.0033 15 0 0 0 4.80E+07 4.91E+07 - - - 7.7668 1 221125_WJC_METTL3_EV_vs_WT_F03.15275.15275.2 2.61E-10 19/32 K.IISNASC[160.03]TTNC[160.03]LAPLAK[136.11].V "sp|P04406|G3P_HUMAN,tr|E7EUT5|E7EUT5_HUMAN" 2 1840.9267 1.11 30815 15275 2 1840.927333 921.4706 Glyceraldehyde-3-phosphate dehydrogenase OS=Homo sapiens OX=9606 GN=GAPDH PE=1 SV=3 8.06 2807.3 - 1.07E+06 - - - 0.3683 - 3.463 0.645 - 732.9 1 2 0 0.0007 17 0 0 0 5.70E+07 5.16E+07 - - - 6.8586 0.9992 221125_WJC_METTL3_EV_vs_WT_F03.15278.15278.3 0.000258 Dec-40 K.HGVVPLATYMR.L "sp|P46778|RL21_HUMAN,tr|G3V1B3|G3V1B3_HUMAN,tr|M0R181|M0R181_HUMAN" 3 1242.6543 0.62 30816 15278 3 1242.648377 415.2254 60S ribosomal protein L21 OS=Homo sapiens OX=9606 GN=RPL21 PE=1 SV=2 8.75 2807.6 - 2.00E+06 - - - -4.7769 - 2.249 0.44 - 213.4 1 2 0 -0.0059 11 0 0 0 3.44E+07 5.58E+07 - - - 5.7464 0.9504 221125_WJC_METTL3_EV_vs_WT_F03.15280.15280.2 0.00062 16-Oct L.FEQYINNLR.R "sp|P48668|K2C6C_HUMAN,sp|P04259|K2C6B_HUMAN,sp|P13647|K2C5_HUMAN,sp|P02538|K2C6A_HUMAN,tr|F8W0C6|F8W0C6_HUMAN" 5 1195.5986 1.64 30818 15280 2 1195.596076 598.8066 "Keratin, type II cytoskeletal 6C OS=Homo sapiens OX=9606 GN=KRT6C PE=1 SV=3" 6 2807.8 - 8.12E+06 - - - -2.0877 - 1.535 0.411 - 345.8 1 1 0 -0.0025 9 0 0 0 1.28E+08 7.78E+07 - - - 3.3156 0.9997 221125_WJC_METTL3_EV_vs_WT_F03.15281.15281.2 0.0896 14/20 K.GALALAQAVQR.A "sp|P11586|C1TC_HUMAN,tr|F5H2F4|F5H2F4_HUMAN,tr|V9GZ78|V9GZ78_HUMAN,tr|V9GYY3|V9GYY3_HUMAN,tr|A0A494C1T2|A0A494C1T2_HUMAN" 5 1096.6353 1.5 30819 15281 2 1096.634038 549.3249 "C-1-tetrahydrofolate synthase, cytoplasmic OS=Homo sapiens OX=9606 GN=MTHFD1 PE=1 SV=4" 9.75 2807.9 - 3.15E+06 - - - -1.1435 - 2.727 0.291 - 693.1 1 2 0 -0.0013 11 0 0 0 1.49E+08 9.90E+07 - - - 3.9038 1 221125_WJC_METTL3_EV_vs_WT_F03.15286.15286.2 2.09E-15 18/32 K.IISNASC[160.03]TTNC[160.03]LAPLAK.V "sp|P04406|G3P_HUMAN,tr|E7EUT5|E7EUT5_HUMAN" 2 1832.9125 1.11 30822 15286 2 1832.908061 917.4635 Glyceraldehyde-3-phosphate dehydrogenase OS=Homo sapiens OX=9606 GN=GAPDH PE=1 SV=3 8.06 2808.5 - 2.91E+06 - - - -2.3973 - 3.617 0.756 - 762.5 1 2 0 -0.0044 17 0 0 0 5.70E+07 5.16E+07 - - - 7.7843 1 221125_WJC_METTL3_EV_vs_WT_F03.15287.15287.2 7.92E-08 16/22 K.EGADEEEWVVAK.D sp|Q9H223|EHD4_HUMAN 1 1360.6147 2.49 30823 15287 2 1360.610461 681.3146 EH domain-containing protein 4 OS=Homo sapiens OX=9606 GN=EHD4 PE=1 SV=1 3.91 2808.7 - 1.67E+06 - - - -3.0979 - 2.75 0.66 - 1150.3 1 2 0 -0.0042 12 0 0 0 3.01E+07 1.21E+07 - - - 6.5761 0.9998 221125_WJC_METTL3_EV_vs_WT_F03.15289.15289.2 9.00E-07 24-Dec R.GEGLVGDGPVDMR.T "sp|Q86YP4|P66A_HUMAN,tr|V9GY85|V9GY85_HUMAN,tr|C9JJK9|C9JJK9_HUMAN,tr|H7C3H1|H7C3H1_HUMAN,tr|C9JVY3|C9JVY3_HUMAN,tr|C9JMI3|C9JMI3_HUMAN,tr|C9JGN4|C9JGN4_HUMAN" 7 1300.6082 2.9 30825 15289 2 1300.605597 651.3114 Transcriptional repressor p66-alpha OS=Homo sapiens OX=9606 GN=GATAD2A PE=1 SV=1 4.03 2808.8 - 2.99E+06 - - - -1.9629 - 2.469 0.517 - 592.7 1 2 0 -0.0026 13 0 0 0 6.41E+07 2.21E+07 - - - 5.1784 0.9996 221125_WJC_METTL3_EV_vs_WT_F03.15290.15290.2 0.000688 18-Nov R.TTALIFSSGK[136.11].M "sp|Q6SJ96|TBPL2_HUMAN,sp|P20226|TBP_HUMAN,tr|A0A1B0GVC6|A0A1B0GVC6_HUMAN,tr|Q32MN6|Q32MN6_HUMAN" 4 1031.5743 0.28 30826 15290 2 1031.573003 516.7944 TATA box-binding protein-like 2 OS=Homo sapiens OX=9606 GN=TBPL2 PE=2 SV=1 8.41 2808.9 - 1.32E+06 - - - -1.2195 - 1.969 0.352 - 315.3 1 2 0 -0.0013 10 0 0 0 4.22E+06 1.49E+07 - - - 3.5317 0.9723 221125_WJC_METTL3_EV_vs_WT_F03.15294.15294.2 0.217 16-Jun R.QDPESLPFR.Q "sp|Q92793|CBP_HUMAN,sp|Q09472|EP300_HUMAN,tr|A0A669KB12|A0A669KB12_HUMAN,tr|I3L466|I3L466_HUMAN" 4 1087.5298 2.1 30830 15294 2 1087.527367 544.7722 CREB-binding protein OS=Homo sapiens OX=9606 GN=CREBBP PE=1 SV=3 4.37 2809.4 - 902634 - - - -2.2592 - 1.301 0.132 - 93.6 3 2 0 -0.0025 9 0 0 0 1.80E+07 8.54E+06 - - - 0.5633 0.9993 221125_WJC_METTL3_EV_vs_WT_F03.15297.15297.2 0.000466 16-Oct R.QLMQSFYSK.A "sp|P39880|CUX1_HUMAN,tr|A0A2R8Y852|A0A2R8Y852_HUMAN" 2 1130.543 0.7 30831 15297 2 1130.540544 566.2788 Homeobox protein cut-like 1 OS=Homo sapiens OX=9606 GN=CUX1 PE=1 SV=3 8.59 2809.8 - 1.78E+06 - - - -2.1998 - 1.819 0.388 - 424.1 1 2 0 -0.0025 9 0 0 0 3.07E+07 4.36E+07 - - - 3.6369 0.9393 221125_WJC_METTL3_EV_vs_WT_F03.15299.15299.2 0.00492 20-Dec R.QTMLFSATQTR.K "sp|Q9NVP1|DDX18_HUMAN,tr|H7C452|H7C452_HUMAN" 2 1282.634 1.04 30833 15299 2 1282.644112 642.3243 ATP-dependent RNA helicase DDX18 OS=Homo sapiens OX=9606 GN=DDX18 PE=1 SV=2 9.75 2810.1 - 2.12E+06 - - - 7.9064 - 1.637 0.329 - 321.2 1 2 0 0.0101 11 0 0 0 2.74E+07 2.63E+07 - - - 2.8011 0.9997 221125_WJC_METTL3_EV_vs_WT_F03.15301.15301.2 0.00407 16-Dec R.K[136.11]PFYPALIR[166.11].Y "sp|O00746|NDKM_HUMAN,tr|Q4TT34|Q4TT34_HUMAN,tr|H0Y6J0|H0Y6J0_HUMAN,tr|F2Z2X0|F2Z2X0_HUMAN,tr|A2IDC9|A2IDC9_HUMAN" 5 1121.6716 2.09 30835 15301 2 1121.672273 561.8431 "Nucleoside diphosphate kinase, mitochondrial OS=Homo sapiens OX=9606 GN=NME4 PE=1 SV=1" 9.99 2810.4 - 1.96E+06 - - - 0.5813 - 1.971 0.395 - 524.2 1 2 0 0.0007 9 0 0 0 4.87E+07 2.33E+07 - - - 3.9213 1 221125_WJC_METTL3_EV_vs_WT_F03.15302.15302.2 5.54E-09 15/26 R.YYTSASGDEMVSLK.D sp|P07900|HS90A_HUMAN 1 1549.697 0.28 30836 15302 2 1549.694335 775.8558 Heat shock protein HSP 90-alpha OS=Homo sapiens OX=9606 GN=HSP90AA1 PE=1 SV=5 4.37 2810.5 - 1.77E+06 - - - -1.7358 - 2.599 0.657 - 509.1 1 2 0 -0.0027 14 0 0 0 2.43E+07 8.74E+07 - - - 6.2896 1 221125_WJC_METTL3_EV_vs_WT_F03.15304.15304.2 1.19E-06 14/28 R.VDVAVNC[160.03]AGIAVASK[136.11].T "sp|Q99714|HCD2_HUMAN,tr|Q5H928|Q5H928_HUMAN,tr|A0A804HHW5|A0A804HHW5_HUMAN" 3 1480.7799 0.63 30838 15304 2 1480.781006 741.3972 3-hydroxyacyl-CoA dehydrogenase type-2 OS=Homo sapiens OX=9606 GN=HSD17B10 PE=1 SV=3 5.8 2810.7 - 1.28E+06 - - - 0.7374 - 3.276 0.543 - 515.8 1 2 0 0.0011 15 0 0 0 1.18E+07 1.88E+07 - - - 5.9686 0.9996 221125_WJC_METTL3_EV_vs_WT_F03.15306.15306.2 0.00689 14-Sep R.QMFGQFGK.L "sp|O43251|RFOX2_HUMAN,sp|Q9NWB1|RFOX1_HUMAN,sp|A6NFN3|RFOX3_HUMAN,tr|A0A6Q8PGE0|A0A6Q8PGE0_HUMAN,tr|A0A6Q8PH77|A0A6Q8PH77_HUMAN,tr|A0A286YEU2|A0A286YEU2_HUMAN,tr|A0A087X2B1|A0A087X2B1_HUMAN,tr|F8VR27|F8VR27_HUMAN,tr|B7Z1U7|B7Z1U7_HUMAN,tr|B0QYV1|B0QYV1_HUMAN,tr|A0A6Q8PHA3|A0A6Q8PHA3_HUMAN,tr|A0A3B3ITL7|A0A3B3ITL7_HUMAN,tr|F8VZY7|F8VZY7_HUMAN,tr|B0QYY4|B0QYY4_HUMAN,tr|J3KNW3|J3KNW3_HUMAN,tr|F8VZG9|F8VZG9_HUMAN,tr|J3QRF4|J3QRF4_HUMAN,tr|A0A6Q8PFM4|A0A6Q8PFM4_HUMAN,tr|S4R469|S4R469_HUMAN,tr|A0A804HKG7|A0A804HKG7_HUMAN,tr|A0A0G2JRA5|A0A0G2JRA5_HUMAN,tr|A0A804HJM2|A0A804HJM2_HUMAN,tr|J3QQZ2|J3QQZ2_HUMAN,tr|I3L1D4|I3L1D4_HUMAN,tr|B0QYY7|B0QYY7_HUMAN,tr|A0A0G2JSB3|A0A0G2JSB3_HUMAN" 26 941.4429 1.04 30839 15306 2 941.440985 471.7287 RNA binding protein fox-1 homolog 2 OS=Homo sapiens OX=9606 GN=RBFOX2 PE=1 SV=3 8.75 2811 - 2.10E+07 - - - -2.0585 - 1.628 0.484 - 283.8 1 2 0 -0.0019 8 0 0 0 3.83E+08 3.68E+08 - - - 4.085 1 221125_WJC_METTL3_EV_vs_WT_F03.15307.15307.2 5.64E-12 15/26 R.YYTSASGDEMVSLK[136.11].D sp|P07900|HS90A_HUMAN 1 1557.7112 0.28 30840 15307 2 1557.707861 779.8629 Heat shock protein HSP 90-alpha OS=Homo sapiens OX=9606 GN=HSP90AA1 PE=1 SV=5 4.37 2811.1 - 3.86E+06 - - - -2.1596 - 3.048 0.738 - 464.7 1 2 0 -0.0034 14 0 0 0 2.46E+07 8.83E+07 - - - 7.2876 0.9997 221125_WJC_METTL3_EV_vs_WT_F03.15308.15308.2 0.00696 13/20 K.GALALAQAVQR[166.11].A "sp|P11586|C1TC_HUMAN,tr|F5H2F4|F5H2F4_HUMAN,tr|V9GZ78|V9GZ78_HUMAN,tr|V9GYY3|V9GYY3_HUMAN,tr|A0A494C1T2|A0A494C1T2_HUMAN" 5 1106.6436 1.5 30841 15308 2 1106.642078 554.3291 "C-1-tetrahydrofolate synthase, cytoplasmic OS=Homo sapiens OX=9606 GN=MTHFD1 PE=1 SV=4" 9.75 2811.1 - 7.84E+06 - - - -1.341 - 2.312 0.363 - 788.6 1 2 0 -0.0015 11 0 0 0 1.49E+08 9.90E+07 - - - 3.9889 0.9998 221125_WJC_METTL3_EV_vs_WT_F03.15309.15309.2 0.000423 16-Nov R.VC[160.03]VIDEIGK[136.11].M "sp|Q9BSD7|NTPCR_HUMAN,tr|Q5TDF0|Q5TDF0_HUMAN" 2 1039.5463 1.51 30842 15309 2 1039.54665 520.7804 Cancer-related nucleoside-triphosphatase OS=Homo sapiens OX=9606 GN=NTPCR PE=1 SV=1 4.37 2811.2 - 2.14E+06 - - - 0.3059 - 2.256 0.34 - 462.5 1 2 0 0.0003 9 0 0 0 3.57E+08 2.37E+08 - - - 3.9059 1 221125_WJC_METTL3_EV_vs_WT_F03.15310.15310.3 0.000355 13/36 R.LQSGIC[160.03]HLFR[166.11].E "sp|P14868|SYDC_HUMAN,tr|C9J7S3|C9J7S3_HUMAN,tr|C9JLC1|C9JLC1_HUMAN" 3 1239.6422 0.91 30843 15310 3 1239.640034 414.2213 "Aspartate--tRNA ligase, cytoplasmic OS=Homo sapiens OX=9606 GN=DARS1 PE=1 SV=2" 8.26 2811.3 - 1.99E+06 - - - -1.7328 - 2.56 0.459 - 177.5 1 2 0 -0.0021 10 0 0 0 3.80E+07 4.18E+07 - - - 6.402 0.9997 221125_WJC_METTL3_EV_vs_WT_F03.15311.15311.2 0.00755 16-Sep R.VC[160.03]VIDEIGK.M "sp|Q9BSD7|NTPCR_HUMAN,tr|Q5TDF0|Q5TDF0_HUMAN" 2 1031.5321 1.52 30844 15311 2 1031.530977 516.7733 Cancer-related nucleoside-triphosphatase OS=Homo sapiens OX=9606 GN=NTPCR PE=1 SV=1 4.37 2811.4 - 1.44E+06 - - - -1.1197 - 2.09 0.364 - 316.3 1 2 0 -0.0012 9 0 0 0 3.59E+08 2.37E+08 - - - 3.8618 0.9999 221125_WJC_METTL3_EV_vs_WT_F03.15312.15312.2 1.50E-06 22-Oct K.EGADEEEWVVAK[136.11].D sp|Q9H223|EHD4_HUMAN 1 1368.6289 2.49 30845 15312 2 1368.627401 685.3217 EH domain-containing protein 4 OS=Homo sapiens OX=9606 GN=EHD4 PE=1 SV=1 3.91 2811.5 - 1.25E+06 - - - -1.0777 - 2.291 0.53 - 419.3 1 2 0 -0.0015 12 0 0 0 3.01E+07 1.21E+07 - - - 5.1363 1 221125_WJC_METTL3_EV_vs_WT_F03.15313.15313.2 1.40E-08 16/28 R.VDVAVNC[160.03]AGIAVASK.T "sp|Q99714|HCD2_HUMAN,tr|Q5H928|Q5H928_HUMAN,tr|A0A804HHW5|A0A804HHW5_HUMAN" 3 1472.7657 0.63 30846 15313 2 1472.761643 737.3901 3-hydroxyacyl-CoA dehydrogenase type-2 OS=Homo sapiens OX=9606 GN=HSD17B10 PE=1 SV=3 5.8 2811.6 - 1.07E+06 - - - -2.7642 - 3.132 0.549 - 1133.9 1 2 0 -0.0041 15 0 0 0 1.18E+07 1.88E+07 - - - 5.9015 0.9998 221125_WJC_METTL3_EV_vs_WT_F03.15314.15314.2 5.94E-07 15/28 K.AGGPAAAEPLLAAEK[136.11].A sp|Q587I9|SFT2C_HUMAN 1 1372.7442 1.13 30847 15314 2 1372.745274 687.3794 Vesicle transport protein SFT2C OS=Homo sapiens OX=9606 GN=SFT2D3 PE=2 SV=1 4.53 2811.7 - 929538 - - - 0.7969 - 2.955 0.402 - 787.6 1 2 0 0.0011 15 0 0 0 1.97E+07 1.75E+07 - - - 4.6737 0.9787 221125_WJC_METTL3_EV_vs_WT_F03.15315.15315.2 0.516 28-Aug K.GVTIVKPIVYGNVAR.Y "sp|O95619|YETS4_HUMAN,tr|F8W1B9|F8W1B9_HUMAN,tr|F8W0J4|F8W0J4_HUMAN" 3 1584.9352 -1 30848 15315 2 1584.93218 793.4749 YEATS domain-containing protein 4 OS=Homo sapiens OX=9606 GN=YEATS4 PE=1 SV=1 9.99 2811.9 - 518444 - - - -1.8815 - 1.369 0.102 - 131.4 1 2 0 -0.003 15 0 0 0 0.00E+00 0.00E+00 - - - 0.5656 0.9999 221125_WJC_METTL3_EV_vs_WT_F03.15317.15317.2 0.00155 20-Nov R.YALYDATYETK[136.11].E "sp|P23528|COF1_HUMAN,sp|Q9Y281|COF2_HUMAN,tr|E9PP50|E9PP50_HUMAN,tr|G3V1A4|G3V1A4_HUMAN,tr|E9PQB7|E9PQB7_HUMAN,tr|E9PK25|E9PK25_HUMAN,tr|E9PLJ3|E9PLJ3_HUMAN" 7 1344.6329 1.32 30849 15317 2 1344.63351 673.3237 Cofilin-1 OS=Homo sapiens OX=9606 GN=CFL1 PE=1 SV=3 4.37 2812.1 - 1.25E+07 - - - 0.4551 - 2.374 0.499 - 324.8 1 2 0 0.0006 11 0 0 0 1.62E+09 1.22E+09 - - - 5.0653 0.9996 221125_WJC_METTL3_EV_vs_WT_F03.15318.15318.3 1.21E-06 Dec-40 K.HGVVPLATYMR[166.11].L "sp|P46778|RL21_HUMAN,tr|G3V1B3|G3V1B3_HUMAN,tr|M0R181|M0R181_HUMAN" 3 1252.6626 0.63 30850 15318 3 1252.664946 418.5615 60S ribosomal protein L21 OS=Homo sapiens OX=9606 GN=RPL21 PE=1 SV=2 8.75 2812.1 - 1.38E+06 - - - 1.8864 - 2.402 0.315 - 241.9 1 2 0 0.0024 11 0 0 0 3.42E+07 5.47E+07 - - - 4.5407 0.9999 221125_WJC_METTL3_EV_vs_WT_F03.15320.15320.3 1.99E-08 22/48 R.TEPELLVAHAYTR[166.11].Y "sp|P09601|HMOX1_HUMAN,tr|B1AHA8|B1AHA8_HUMAN,tr|A0A7I2V3I1|A0A7I2V3I1_HUMAN" 3 1508.7863 1.82 30852 15320 3 1508.781384 503.936 Heme oxygenase 1 OS=Homo sapiens OX=9606 GN=HMOX1 PE=1 SV=1 5.37 2812.3 - 3.22E+06 - - - -3.2337 - 3.765 0.5 - 821.3 1 2 0 -0.0049 13 0 0 0 6.90E+07 3.79E+07 - - - 7.7076 0.9987 221125_WJC_METTL3_EV_vs_WT_F03.15322.15322.3 0.00761 Sep-36 K.KLGEWVGLC[160.03]K.L sp|P25398|RS12_HUMAN 1 1188.6325 1.36 30854 15322 3 1188.631762 397.2181 40S ribosomal protein S12 OS=Homo sapiens OX=9606 GN=RPS12 PE=1 SV=3 8.2 2812.5 - 1.97E+06 - - - -0.6335 - 1.546 0.297 - 164.5 1 2 0 -0.0008 10 0 0 0 1.42E+07 1.04E+07 - - - 3.1234 0.997 221125_WJC_METTL3_EV_vs_WT_F03.15323.15323.3 8.64E-06 16/44 F.YYLLSGAGEHLK[136.11].T sp|P35579|MYH9_HUMAN 1 1357.7122 0.68 30855 15323 3 1357.712256 453.578 Myosin-9 OS=Homo sapiens OX=9606 GN=MYH9 PE=1 SV=4 6.75 2812.6 - 1.68E+06 - - - 0.0766 - 2.406 0.5 - 187.4 1 1 0 0.0001 12 0 0 0 1.75E+07 2.57E+07 - - - 6.5481 0.9999 221125_WJC_METTL3_EV_vs_WT_F03.15324.15324.3 5.43E-06 Dec-40 R.TAAENEFVTLK.K "sp|P48668|K2C6C_HUMAN,sp|P12035|K2C3_HUMAN,sp|P04259|K2C6B_HUMAN,sp|P02538|K2C6A_HUMAN" 4 1221.6241 0.62 30856 15324 3 1221.620971 408.2153 "Keratin, type II cytoskeletal 6C OS=Homo sapiens OX=9606 GN=KRT6C PE=1 SV=3" 4.53 2812.7 - 1.53E+06 - - - -2.5761 - 2.552 0.436 - 215.1 1 2 0 -0.0031 11 0 0 0 2.35E+07 3.80E+07 - - - 6.0616 1 221125_WJC_METTL3_EV_vs_WT_F03.15325.15325.2 1.28E-09 16/28 R.MGQMAMGGAMGINNR.G "sp|Q15233|NONO_HUMAN,tr|A0A7I2V535|A0A7I2V535_HUMAN,tr|A0A7I2V4K9|A0A7I2V4K9_HUMAN,tr|A0A7P0MRW0|A0A7P0MRW0_HUMAN,tr|A0A7I2V4J2|A0A7I2V4J2_HUMAN,tr|A0A7I2V5Y7|A0A7I2V5Y7_HUMAN" 6 1537.6622 0.83 30857 15325 2 1537.658672 769.8384 Non-POU domain-containing octamer-binding protein OS=Homo sapiens OX=9606 GN=NONO PE=1 SV=4 9.5 2812.8 - 1.47E+06 - - - -2.2898 - 3.158 0.646 - 953.6 1 2 0 -0.0035 15 0 0 0 2.21E+07 2.65E+07 - - - 6.6384 0.9995 221125_WJC_METTL3_EV_vs_WT_F03.15326.15326.3 0.0152 13/48 K.ISAILHPSTYLNK.L "sp|Q8NI36|WDR36_HUMAN,tr|A0A0A0MTB8|A0A0A0MTB8_HUMAN" 2 1455.8086 0.75 30858 15326 3 1455.807733 486.2768 WD repeat-containing protein 36 OS=Homo sapiens OX=9606 GN=WDR36 PE=1 SV=1 8.6 2813 - 862250 - - - -0.5715 - 2.195 0.288 - 193.7 1 2 0 -0.0008 13 0 0 0 1.01E+07 1.34E+07 - - - 3.8823 1 221125_WJC_METTL3_EV_vs_WT_F03.15327.15327.2 2.97E-09 18/32 R.ALIGATNPADAPPGTIR.G "sp|Q13232|NDK3_HUMAN,tr|H3BPR2|H3BPR2_HUMAN" 2 1633.8788 0.26 30859 15327 2 1633.877796 817.9467 Nucleoside diphosphate kinase 3 OS=Homo sapiens OX=9606 GN=NME3 PE=1 SV=2 5.88 2813.1 - 660039 - - - -0.5961 - 3.365 0.575 - 893.6 1 2 0 -0.001 17 0 0 0 4.43E+07 1.71E+08 - - - 6.2709 0.9999 221125_WJC_METTL3_EV_vs_WT_F03.15329.15329.2 1.24E-07 20-Oct R.YALYDATYETK.E "sp|P23528|COF1_HUMAN,sp|Q9Y281|COF2_HUMAN,tr|E9PP50|E9PP50_HUMAN,tr|G3V1A4|G3V1A4_HUMAN,tr|E9PQB7|E9PQB7_HUMAN,tr|E9PK25|E9PK25_HUMAN,tr|E9PLJ3|E9PLJ3_HUMAN" 7 1336.6187 1.33 30860 15329 2 1336.617318 669.3166 Cofilin-1 OS=Homo sapiens OX=9606 GN=CFL1 PE=1 SV=3 4.37 2813.3 - 8.77E+06 - - - -1.0325 - 2.12 0.594 - 271.5 1 2 0 -0.0014 11 0 0 0 1.62E+09 1.22E+09 - - - 5.4606 0.9998 221125_WJC_METTL3_EV_vs_WT_F03.15330.15330.3 0.000342 16/44 R.LAILGIHNEVSK.L "sp|P12814|ACTN1_HUMAN,tr|A0A804HK61|A0A804HK61_HUMAN,tr|H7C5W8|H7C5W8_HUMAN,tr|A0A804HJU8|A0A804HJU8_HUMAN,tr|A0A804HIN7|A0A804HIN7_HUMAN,tr|H9KV75|H9KV75_HUMAN,tr|A0A7I2V4Y4|A0A7I2V4Y4_HUMAN,tr|A0A804HII9|A0A804HII9_HUMAN,tr|A0A804HL31|A0A804HL31_HUMAN,tr|A0A804HKE2|A0A804HKE2_HUMAN,tr|A0A804HLD0|A0A804HLD0_HUMAN" 11 1292.7452 0.52 30861 15330 3 1292.743859 431.9224 Alpha-actinin-1 OS=Homo sapiens OX=9606 GN=ACTN1 PE=1 SV=2 6.75 2813.4 - 1.40E+06 - - - -1.0652 - 2.987 0.275 - 443.1 1 2 0 -0.0014 12 0 0 0 1.75E+07 3.36E+07 - - - 4.6388 1 221125_WJC_METTL3_EV_vs_WT_F03.15332.15332.2 4.83E-08 19/30 N.TLAVNAAQDSTDLVAK.L "sp|P17987|TCPA_HUMAN,tr|F5H282|F5H282_HUMAN,tr|E7EQR6|E7EQR6_HUMAN" 3 1615.8417 0.49 30863 15332 2 1615.83944 808.9281 T-complex protein 1 subunit alpha OS=Homo sapiens OX=9606 GN=TCP1 PE=1 SV=1 4.21 2813.6 - 2.68E+06 - - - -1.4079 - 3.679 0.642 - 1079.7 1 1 0 -0.0023 16 0 0 0 5.07E+07 1.04E+08 - - - 6.9847 0.9948 221125_WJC_METTL3_EV_vs_WT_F03.15334.15334.3 0.000506 13/44 F.YYLLSGAGEHLK.T sp|P35579|MYH9_HUMAN 1 1349.698 0.75 30865 15334 3 1349.696557 450.9066 Myosin-9 OS=Homo sapiens OX=9606 GN=MYH9 PE=1 SV=4 6.75 2813.9 - 1.52E+06 - - - -1.0336 - 1.968 0.495 - 126.6 1 1 0 -0.0014 12 0 0 0 1.71E+07 2.27E+07 - - - 5.935 0.992 221125_WJC_METTL3_EV_vs_WT_F03.15335.15335.2 2.80E-07 16-Nov L.VNHFVEEFK.R "sp|P0DMV8|HS71A_HUMAN,sp|P0DMV9|HS71B_HUMAN,tr|V9GZ37|V9GZ37_HUMAN,tr|A0A0G2JIW1|A0A0G2JIW1_HUMAN" 4 1147.5662 0.09 30866 15335 2 1147.567498 574.7904 Heat shock 70 kDa protein 1A OS=Homo sapiens OX=9606 GN=HSPA1A PE=1 SV=1 5.4 2813.9 - 1.13E+06 - - - 1.1232 - 2.207 0.541 - 525.9 1 1 0 0.0013 9 0 0 0 6.05E+07 6.44E+08 - - - 5.3267 0.9981 221125_WJC_METTL3_EV_vs_WT_F03.15338.15338.2 0.0187 18-Oct R.SQMLAMNIEK[136.11].K "sp|P60228|EIF3E_HUMAN,tr|H0YBP5|H0YBP5_HUMAN,tr|A0A7I2V5Z6|A0A7I2V5Z6_HUMAN,tr|A0A7I2V2H9|A0A7I2V2H9_HUMAN,tr|B3KW56|B3KW56_HUMAN,tr|H0YAW4|H0YAW4_HUMAN,tr|A0A7I2V4B4|A0A7I2V4B4_HUMAN,tr|E5RGA2|E5RGA2_HUMAN,tr|A0A7I2V3I0|A0A7I2V3I0_HUMAN,tr|A0A7I2V3S3|A0A7I2V3S3_HUMAN,tr|A0A7I2V4G3|A0A7I2V4G3_HUMAN,tr|E5RHS5|E5RHS5_HUMAN,tr|A0A7I2V2W0|A0A7I2V2W0_HUMAN,tr|A0A7I2V5P9|A0A7I2V5P9_HUMAN" 14 1171.5821 0.95 30869 15338 2 1171.584469 586.7983 Eukaryotic translation initiation factor 3 subunit E OS=Homo sapiens OX=9606 GN=EIF3E PE=1 SV=1 5.72 2814.3 - 656532 - - - 2.0519 - 1.861 0.241 - 290.7 1 2 0 0.0024 10 0 0 0 3.24E+07 3.43E+07 - - - 2.554 0.9994 221125_WJC_METTL3_EV_vs_WT_F03.15339.15339.3 0.00205 Nov-40 R.NPEAALSPTFR[166.11].S "sp|Q86U44|MTA70_HUMAN,tr|B4E349|B4E349_HUMAN,tr|F5H6D8|F5H6D8_HUMAN,tr|B4DTN4|B4DTN4_HUMAN" 4 1211.6174 0.02 30870 15339 3 1211.614156 404.8797 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 6 2814.4 - 397020 - - - -2.6832 - 2.079 0.353 - 131.8 1 2 0 -0.0033 11 0 0 0 7.57E+04 3.33E+06 - - - 4.5539 1 221125_WJC_METTL3_EV_vs_WT_F03.15345.15345.3 2.09E-06 16/48 R.TEPELLVAHAYTR.Y "sp|P09601|HMOX1_HUMAN,tr|B1AHA8|B1AHA8_HUMAN,tr|A0A7I2V3I1|A0A7I2V3I1_HUMAN" 3 1498.778 1.79 30874 15345 3 1498.777402 500.5999 Heme oxygenase 1 OS=Homo sapiens OX=9606 GN=HMOX1 PE=1 SV=1 5.37 2814.9 - 4.48E+06 - - - -0.3943 - 2.918 0.554 - 465.7 1 2 0 -0.0006 13 0 0 0 6.96E+07 3.89E+07 - - - 7.6199 0.9838 221125_WJC_METTL3_EV_vs_WT_F03.15346.15346.2 8.34E-05 18-Sep R.MDSFDEDLAR.P "sp|Q9Y2W1|TR150_HUMAN,tr|A0A3B3ITZ9|A0A3B3ITZ9_HUMAN" 2 1197.4972 2.99 30875 15346 2 1197.494637 599.7559 Thyroid hormone receptor-associated protein 3 OS=Homo sapiens OX=9606 GN=THRAP3 PE=1 SV=2 3.84 2814.9 - 1.80E+06 - - - -2.1428 - 2.061 0.528 - 293.6 1 1 0 -0.0026 10 0 0 0 1.64E+09 5.48E+08 - - - 4.9586 1 221125_WJC_METTL3_EV_vs_WT_F03.15349.15349.3 2.22E-06 15/36 R.R[166.11]ILDSAEFIK[136.11].F "sp|P78347|GTF2I_HUMAN,tr|A0A494C1K3|A0A494C1K3_HUMAN" 2 1208.6884 1.68 30878 15349 3 1208.688322 403.9034 General transcription factor II-I OS=Homo sapiens OX=9606 GN=GTF2I PE=1 SV=2 6.07 2815.3 - 723047 - - - -0.0587 - 3.24 0.56 - 409.3 1 2 0 -0.0001 10 0 0 0 1.31E+08 7.76E+07 - - - 8.2166 0.9993 221125_WJC_METTL3_EV_vs_WT_F03.15351.15351.2 1.49E-05 19/32 R.ALIGATNPADAPPGTIR[166.11].G "sp|Q13232|NDK3_HUMAN,tr|H3BPR2|H3BPR2_HUMAN" 2 1643.887 0.26 30880 15351 2 1643.8811 822.9508 Nucleoside diphosphate kinase 3 OS=Homo sapiens OX=9606 GN=NME3 PE=1 SV=2 5.88 2815.5 - 446647 - - - -3.6134 - 3.08 0.467 - 1024.5 1 2 0 -0.0059 17 0 0 0 4.43E+07 1.72E+08 - - - 5.2541 0.9999 221125_WJC_METTL3_EV_vs_WT_F03.15354.15354.2 8.69E-05 18-Nov K.ESALTLAC[160.03]YK.G "sp|O75179|ANR17_HUMAN,sp|Q8IWZ3|ANKH1_HUMAN,tr|E9PDP5|E9PDP5_HUMAN,tr|H0YM23|H0YM23_HUMAN,tr|A0A1W2PQ15|A0A1W2PQ15_HUMAN,tr|D6RHC4|D6RHC4_HUMAN" 6 1154.5642 1.62 30881 15354 2 1154.564568 578.2894 Ankyrin repeat domain-containing protein 17 OS=Homo sapiens OX=9606 GN=ANKRD17 PE=1 SV=3 6.09 2815.9 - 4.84E+06 - - - 0.3525 - 2.226 0.463 - 489.6 1 2 0 0.0004 10 0 0 0 5.93E+07 3.66E+07 - - - 4.6942 0.9992 221125_WJC_METTL3_EV_vs_WT_F03.15355.15355.2 0.329 16-Aug R.KPFYPALIR.Y "sp|O00746|NDKM_HUMAN,tr|Q4TT34|Q4TT34_HUMAN,tr|H0Y6J0|H0Y6J0_HUMAN,tr|F2Z2X0|F2Z2X0_HUMAN,tr|A2IDC9|A2IDC9_HUMAN" 5 1103.6492 2.21 30882 15355 2 1103.650071 552.8319 "Nucleoside diphosphate kinase, mitochondrial OS=Homo sapiens OX=9606 GN=NME4 PE=1 SV=1" 9.99 2816 - 5.02E+06 - - - 0.8336 - 1.639 0.31 - 203.6 1 2 0 0.0009 9 0 0 0 6.03E+07 2.73E+07 - - - 2.7598 1 221125_WJC_METTL3_EV_vs_WT_F03.15356.15356.3 4.27E-06 13/36 R.RILDSAEFIK.F "sp|P78347|GTF2I_HUMAN,tr|A0A494C1K3|A0A494C1K3_HUMAN" 2 1190.6659 1.6 30883 15356 3 1190.667798 397.8959 General transcription factor II-I OS=Homo sapiens OX=9606 GN=GTF2I PE=1 SV=2 6.07 2816.1 - 1.55E+06 - - - 1.5747 - 2.773 0.47 - 339.8 1 2 0 0.0019 10 0 0 0 1.24E+08 7.74E+07 - - - 6.7582 0.9999 221125_WJC_METTL3_EV_vs_WT_F03.15357.15357.2 9.31E-07 13/22 K.LSVISVEDPPQR[166.11].T sp|P38117|ETFB_HUMAN 1 1348.7226 1.72 30884 15357 2 1348.723635 675.3686 Electron transfer flavoprotein subunit beta OS=Homo sapiens OX=9606 GN=ETFB PE=1 SV=3 4.37 2816.2 - 1.30E+06 - - - 0.7674 - 2.391 0.486 - 364.8 1 2 0 0.001 12 0 0 0 2.35E+08 1.36E+08 - - - 4.9239 1 221125_WJC_METTL3_EV_vs_WT_F03.15359.15359.2 1.14E-09 20/30 R.VADLTEQYNEQYGAVR.T sp|Q9BWF3|RBM4_HUMAN 1 1854.8748 1.35 30886 15359 2 1854.878588 928.4447 RNA-binding protein 4 OS=Homo sapiens OX=9606 GN=RBM4 PE=1 SV=1 4.14 2816.5 - 945060 - - - 2.0384 - 3.721 0.68 - 1414.3 1 2 0 0.0038 16 0 0 0 1.43E+07 1.06E+07 - - - 7.2928 0.961 221125_WJC_METTL3_EV_vs_WT_F03.15360.15360.2 0.461 22-Aug R.NLQMTAASR[166.11]C[160.03]PR.R "tr|J3QTB1|J3QTB1_HUMAN,tr|A0A494C0T1|A0A494C0T1_HUMAN" 2 1413.6845 - 30887 15360 2 1413.685254 707.8495 Stimulator of interferon genes protein OS=Homo sapiens OX=9606 GN=STING1 PE=1 SV=2 10.35 2816.6 - 829059 - - - 0.5638 - 1.577 0.178 - 264.8 2 2 1 0.0008 12 0 0 0 - - - - - 1.4195 1 221125_WJC_METTL3_EV_vs_WT_F03.15362.15362.2 3.44E-06 20/30 R.VADLTEQYNEQYGAVR[166.11].T sp|Q9BWF3|RBM4_HUMAN 1 1864.8831 1.35 30889 15362 2 1864.879589 933.4488 RNA-binding protein 4 OS=Homo sapiens OX=9606 GN=RBM4 PE=1 SV=1 4.14 2816.8 - 758127 - - - -1.8704 - 3.51 0.63 - 1104.7 1 2 0 -0.0035 16 0 0 0 1.43E+07 1.06E+07 - - - 6.7801 1 221125_WJC_METTL3_EV_vs_WT_F03.15363.15363.2 2.57E-06 24-Dec R.QFMAETQFTSGEK[136.11].E "sp|Q14444|CAPR1_HUMAN,tr|G3V153|G3V153_HUMAN" 2 1510.6853 0.92 30890 15363 2 1510.686146 756.3499 Caprin-1 OS=Homo sapiens OX=9606 GN=CAPRIN1 PE=1 SV=2 4.53 2817 - 689453 - - - 0.5302 - 2.402 0.612 - 476.4 1 2 0 0.0008 13 0 0 0 5.04E+06 5.45E+06 - - - 5.81 1 221125_WJC_METTL3_EV_vs_WT_F03.15364.15364.2 1.70E-07 15/26 K.VGAEDADGIDMAYR.V "sp|P49588|SYAC_HUMAN,tr|A0A6Q8PGR9|A0A6Q8PGR9_HUMAN,tr|A0A6Q8PF77|A0A6Q8PF77_HUMAN,tr|A0A6Q8PHP3|A0A6Q8PHP3_HUMAN,tr|A0A6Q8PFY2|A0A6Q8PFY2_HUMAN,tr|A0A6Q8PFK3|A0A6Q8PFK3_HUMAN,tr|H3BPK7|H3BPK7_HUMAN,tr|A0A6Q8PHJ2|A0A6Q8PHJ2_HUMAN,tr|A0A6Q8PHP7|A0A6Q8PHP7_HUMAN,tr|A0A6Q8PG28|A0A6Q8PG28_HUMAN,tr|A0A6Q8PGE8|A0A6Q8PGE8_HUMAN,tr|A0A6Q8PF33|A0A6Q8PF33_HUMAN,tr|A0A6Q8PGN5|A0A6Q8PGN5_HUMAN,tr|A0A6Q8PH44|A0A6Q8PH44_HUMAN" 14 1481.6457 1.16 30891 15364 2 1481.647498 741.8301 "Alanine--tRNA ligase, cytoplasmic OS=Homo sapiens OX=9606 GN=AARS1 PE=1 SV=2" 3.84 2817.1 - 680088 - - - 1.2419 - 2.826 0.607 - 649.1 1 2 0 0.0018 14 0 0 0 5.76E+06 4.98E+06 - - - 6.1307 0.8593 221125_WJC_METTL3_EV_vs_WT_F03.15368.15368.2 3.96E-05 20-Oct R.R[166.11]FDDAVVQSDM.K "sp|P11142|HSP7C_HUMAN,tr|E9PQQ4|E9PQQ4_HUMAN,tr|E9PNE6|E9PNE6_HUMAN,tr|E9PKE3|E9PKE3_HUMAN,tr|E9PN89|E9PN89_HUMAN,tr|E9PLF4|E9PLF4_HUMAN,tr|E9PK54|E9PK54_HUMAN,tr|E9PN25|E9PN25_HUMAN,tr|E9PPY6|E9PPY6_HUMAN,tr|E9PQK7|E9PQK7_HUMAN" 10 1291.5742 0.04 30895 15368 2 1291.567546 646.7944 Heat shock cognate 71 kDa protein OS=Homo sapiens OX=9606 GN=HSPA8 PE=1 SV=1 3.93 2817.6 - 478735 - - - -5.1681 - 2.096 0.508 - 373.8 1 1 0 -0.0067 11 0 0 0 1.46E+05 3.73E+06 - - - 4.793 0.9998 221125_WJC_METTL3_EV_vs_WT_F03.15375.15375.2 1.59E-06 16-Aug K.GNFSSFMQK.E "sp|Q06210|GFPT1_HUMAN,tr|A0A6I8PRN4|A0A6I8PRN4_HUMAN,tr|A0A6I8PTT9|A0A6I8PTT9_HUMAN" 3 1044.4699 1.42 30900 15375 2 1044.470851 523.2422 Glutamine--fructose-6-phosphate aminotransferase [isomerizing] 1 OS=Homo sapiens OX=9606 GN=GFPT1 PE=1 SV=3 8.75 2818.3 - 2.86E+06 - - - 0.9431 - 1.75 0.554 - 238.2 1 2 0 0.001 9 0 0 0 6.88E+07 4.85E+07 - - - 4.7515 0.9999 221125_WJC_METTL3_EV_vs_WT_F03.15376.15376.2 6.14E-05 18-Sep R.ADMEDLMSSK[136.11].D sp|P35580|MYH10_HUMAN 1 1133.4824 0.92 30901 15376 2 1133.482406 567.7485 Myosin-10 OS=Homo sapiens OX=9606 GN=MYH10 PE=1 SV=3 4.03 2818.4 - 1.47E+06 - - - -0.0044 - 1.895 0.58 - 286.4 1 2 0 0 10 0 0 0 1.65E+07 1.80E+07 - - - 5.1091 0.9968 221125_WJC_METTL3_EV_vs_WT_F03.15377.15377.2 0.109 16-Aug K.DLSELGSVR.T "sp|Q15149|PLEC_HUMAN,tr|H0YDN1|H0YDN1_HUMAN" 2 974.5033 1.03 30902 15377 2 974.505269 488.2589 Plectin OS=Homo sapiens OX=9606 GN=PLEC PE=1 SV=3 4.37 2818.5 - 1.47E+06 - - - 2.0462 - 1.595 0.235 - 195.2 1 2 0 0.002 9 0 0 0 1.17E+07 1.13E+07 - - - 2.1268 1 221125_WJC_METTL3_EV_vs_WT_F03.15378.15378.3 0.00628 18/48 R.IAQLEAELALQK[136.11]K[136.11].Y sp|Q15007|FL2D_HUMAN 1 1469.8788 0.7 30903 15378 3 1469.877737 490.9669 Pre-mRNA-splicing regulator WTAP OS=Homo sapiens OX=9606 GN=WTAP PE=1 SV=2 6.14 2818.6 - 778805 - - - -0.7436 - 3.311 0.443 - 486.6 1 2 0 -0.0011 13 0 0 0 5.99E+06 8.53E+06 - - - 6.7248 0.9999 221125_WJC_METTL3_EV_vs_WT_F03.15379.15379.2 0.000674 20-Dec K.SLLEIQQEEAR[166.11].Q "sp|Q6Y7W6|GGYF2_HUMAN,tr|A0A7I2V3H7|A0A7I2V3H7_HUMAN,tr|I1E4Y6|I1E4Y6_HUMAN,tr|A0A7I2V516|A0A7I2V516_HUMAN,tr|A0A7I2V3H0|A0A7I2V3H0_HUMAN,tr|A0A7I2V361|A0A7I2V361_HUMAN" 6 1324.6862 2.81 30904 15379 2 1324.686944 663.3504 GRB10-interacting GYF protein 2 OS=Homo sapiens OX=9606 GN=GIGYF2 PE=1 SV=1 4.25 2818.8 - 752753 - - - 0.5503 - 2.764 0.446 - 696.3 1 2 0 0.0007 11 0 0 0 3.55E+08 1.26E+08 - - - 5.0853 1 221125_WJC_METTL3_EV_vs_WT_F03.15381.15381.3 7.23E-05 19/64 R.ALIGATNPADAPPGTIR.G "sp|Q13232|NDK3_HUMAN,tr|H3BPR2|H3BPR2_HUMAN" 2 1633.8788 0.01 30906 15381 3 1633.878796 545.6335 Nucleoside diphosphate kinase 3 OS=Homo sapiens OX=9606 GN=NME3 PE=1 SV=2 5.88 2819 - 615106 - - - 0.0159 - 2.742 0.467 - 425.3 1 2 0 0 17 0 0 0 2.11E+07 1.97E+09 - - - 6.2948 0.9996 221125_WJC_METTL3_EV_vs_WT_F03.15383.15383.3 0.0173 14/48 R.IAQLEAELALQKK.Y sp|Q15007|FL2D_HUMAN 1 1453.8504 0.7 30908 15383 3 1453.850871 485.6241 Pre-mRNA-splicing regulator WTAP OS=Homo sapiens OX=9606 GN=WTAP PE=1 SV=2 6.14 2819.3 - 586744 - - - 0.3033 - 2.385 0.27 - 285.7 1 2 0 0.0004 13 0 0 0 5.99E+06 8.53E+06 - - - 3.9068 0.9978 221125_WJC_METTL3_EV_vs_WT_F03.15385.15385.3 0.0276 Nov-32 K.K[136.11]LVWIPSER[166.11].H "sp|P35580|MYH10_HUMAN,tr|E7ERA5|E7ERA5_HUMAN" 2 1144.6723 0.001 30910 15385 3 1144.671715 382.5647 Myosin-10 OS=Homo sapiens OX=9606 GN=MYH10 PE=1 SV=3 8.75 2819.6 - 501945 - - - -0.5539 - 1.947 0.199 - 192.4 1 2 0 -0.0006 9 0 0 0 0.00E+00 1.78E+07 - - - 2.7665 0.9696 221125_WJC_METTL3_EV_vs_WT_F03.15389.15389.2 0.00225 20-Aug K.GAVDGGLSIPH.S "sp|P46777|RL5_HUMAN,tr|A0A2R8Y6J3|A0A2R8Y6J3_HUMAN,tr|Q5T7N0|Q5T7N0_HUMAN" 3 1021.5193 - 30914 15389 2 1021.519126 511.7669 60S ribosomal protein L5 OS=Homo sapiens OX=9606 GN=RPL5 PE=1 SV=3 5.08 2820.1 - 431985 - - - -0.1302 - 1.623 0.355 - 145.6 1 1 0 -0.0001 11 0 0 0 - - - - - 2.9731 1 221125_WJC_METTL3_EV_vs_WT_F03.15394.15394.2 0.00139 18-Nov R.MDSFDEDLAR[166.11].P "sp|Q9Y2W1|TR150_HUMAN,tr|A0A3B3ITZ9|A0A3B3ITZ9_HUMAN" 2 1207.5055 2.99 30917 15394 2 1207.505717 604.76 Thyroid hormone receptor-associated protein 3 OS=Homo sapiens OX=9606 GN=THRAP3 PE=1 SV=2 3.84 2820.7 - 1.87E+07 - - - 0.2021 - 2.407 0.576 - 645.1 1 1 0 0.0002 10 0 0 0 1.64E+09 5.48E+08 - - - 5.7471 1 221125_WJC_METTL3_EV_vs_WT_F03.15397.15397.2 1.73E-09 17/26 K.AEAGAGSATEFQFR.G "sp|Q9NQ39|RS10L_HUMAN,sp|P46783|RS10_HUMAN" 2 1440.6634 1.36 30920 15397 2 1440.661443 721.339 Putative 40S ribosomal protein S10-like OS=Homo sapiens OX=9606 GN=RPS10P5 PE=5 SV=1 4.53 2820.9 - 4.64E+06 - - - -1.3286 - 3.572 0.554 - 1196.5 1 2 0 -0.0019 14 0 0 0 2.33E+08 1.71E+08 - - - 6.3271 0.9999 221125_WJC_METTL3_EV_vs_WT_F03.15398.15398.2 5.23E-05 16-Oct K.DTGDIFC[160.03]TR.S sp|Q08554|DSC1_HUMAN 1 1083.4655 111.71 30921 15398 2 1083.465657 542.74 Desmocollin-1 OS=Homo sapiens OX=9606 GN=DSC1 PE=1 SV=2 4.21 2820.9 - 2.66E+06 - - - 0.1366 - 1.863 0.57 - 396.5 1 2 0 0.0001 9 0 0 0 1.00E+08 8.98E+05 - - - 5.051 0.9999 221125_WJC_METTL3_EV_vs_WT_F03.15399.15399.3 0.000848 13/36 R.SLHDAIMIVR[166.11].R sp|Q99832|TCPH_HUMAN 1 1163.636 0.16 30922 15399 3 1163.635407 388.886 T-complex protein 1 subunit eta OS=Homo sapiens OX=9606 GN=CCT7 PE=1 SV=2 6.46 2821 - 2.27E+06 - - - -0.5388 - 2.211 0.427 - 274.1 1 2 0 -0.0006 10 0 0 0 9.63E+07 5.87E+08 - - - 5.6177 0.9999 221125_WJC_METTL3_EV_vs_WT_F03.15400.15400.2 0.000986 16-Aug K.WDYMTPEQR[166.11].R sp|Q10471|GALT2_HUMAN 1 1234.5316 1.46 30923 15400 2 1234.530768 618.2731 Polypeptide N-acetylgalactosaminyltransferase 2 OS=Homo sapiens OX=9606 GN=GALNT2 PE=1 SV=1 4.37 2821.1 - 1.86E+06 - - - -0.6966 - 1.864 0.514 - 318.8 1 2 0 -0.0009 9 0 0 0 5.03E+07 3.44E+07 - - - 4.6387 0.995 221125_WJC_METTL3_EV_vs_WT_F03.15403.15403.3 0.028 Dec-44 K.NKLEGLEDALQK.A "sp|P48668|K2C6C_HUMAN,sp|P04259|K2C6B_HUMAN,sp|P02538|K2C6A_HUMAN" 3 1356.7249 41.4 30926 15403 3 1356.723136 453.2489 "Keratin, type II cytoskeletal 6C OS=Homo sapiens OX=9606 GN=KRT6C PE=1 SV=3" 4.68 2821.4 - 866830 - - - -1.2965 - 2.012 0.258 - 154 1 2 1 -0.0018 12 0 0 0 1.52E+07 3.67E+05 - - - 3.3538 0.9998 221125_WJC_METTL3_EV_vs_WT_F03.15408.15408.2 7.60E-05 18-Oct R.SISLYYTGEK[136.11].G "sp|P19338|NUCL_HUMAN,tr|A0A7I2V506|A0A7I2V506_HUMAN,tr|A0A7I2V2U7|A0A7I2V2U7_HUMAN,tr|A0A7I2V3F3|A0A7I2V3F3_HUMAN,tr|A0A7I2V428|A0A7I2V428_HUMAN,tr|A0A7I2V349|A0A7I2V349_HUMAN,tr|H7BY16|H7BY16_HUMAN,tr|A0A7I2V5M5|A0A7I2V5M5_HUMAN,tr|C9JLB1|C9JLB1_HUMAN" 9 1167.5903 0.82 30930 15408 2 1167.591132 584.8024 Nucleolin OS=Homo sapiens OX=9606 GN=NCL PE=1 SV=3 5.72 2822 - 2.67E+07 - - - 0.7083 - 1.837 0.499 - 252.3 1 2 0 0.0008 10 0 0 0 3.62E+08 4.42E+08 - - - 4.4238 0.9997 221125_WJC_METTL3_EV_vs_WT_F03.15410.15410.2 3.06E-05 20-Dec R.YVDIAIPC[160.03]NNK.G "sp|P08865|RSSA_HUMAN,tr|C9J9K3|C9J9K3_HUMAN,tr|A0A0C4DG17|A0A0C4DG17_HUMAN" 3 1305.6387 0.93 30931 15410 2 1305.636274 653.8266 40S ribosomal protein SA OS=Homo sapiens OX=9606 GN=RPSA PE=1 SV=4 5.83 2822.2 - 3.12E+06 - - - -1.8749 - 2.144 0.468 - 427 1 2 0 -0.0024 11 0 0 0 4.57E+07 4.91E+07 - - - 4.5601 0.9937 221125_WJC_METTL3_EV_vs_WT_F03.15412.15412.2 0.352 16-Jul K.WDYMTPEQR.R sp|Q10471|GALT2_HUMAN 1 1224.5234 1.45 30933 15412 2 1224.524674 613.269 Polypeptide N-acetylgalactosaminyltransferase 2 OS=Homo sapiens OX=9606 GN=GALNT2 PE=1 SV=1 4.37 2822.4 - 3.60E+07 - - - 1.0747 - 0.932 0.314 - 74.6 1 2 0 0.0013 9 0 0 0 5.01E+07 3.44E+07 - - - 1.1561 0.9993 221125_WJC_METTL3_EV_vs_WT_F03.15413.15413.2 0.00578 16-Aug K.K[136.11]LVWIPSER[166.11].H "sp|P35580|MYH10_HUMAN,tr|E7ERA5|E7ERA5_HUMAN" 2 1144.6723 0.74 30934 15413 2 1144.672678 573.3435 Myosin-10 OS=Homo sapiens OX=9606 GN=MYH10 PE=1 SV=3 8.75 2822.4 - 1.78E+06 - - - 0.2874 - 1.891 0.25 - 246.6 1 2 0 0.0003 9 0 0 0 1.07E+07 1.44E+07 - - - 2.7306 1 221125_WJC_METTL3_EV_vs_WT_F03.15414.15414.3 5.26E-07 16/48 K.EMNPALGIDC[160.03]LHK[136.11].G "sp|P48643|TCPE_HUMAN,tr|E9PCA1|E9PCA1_HUMAN,tr|B7ZAR1|B7ZAR1_HUMAN,tr|E7ENZ3|E7ENZ3_HUMAN" 4 1504.7258 0.74 30935 15414 3 1504.72449 502.5825 T-complex protein 1 subunit epsilon OS=Homo sapiens OX=9606 GN=CCT5 PE=1 SV=1 5.32 2822.5 - 1.64E+06 - - - -0.8507 - 2.856 0.6 - 348.2 1 2 0 -0.0013 13 0 0 0 1.20E+07 1.62E+07 - - - 8.0743 0.9998 221125_WJC_METTL3_EV_vs_WT_F03.15416.15416.3 0.0029 Dec-52 K.AEAGAGSATEFQFR[166.11].G "sp|Q9NQ39|RS10L_HUMAN,sp|P46783|RS10_HUMAN" 2 1450.6716 1.38 30937 15416 3 1450.670644 484.5645 Putative 40S ribosomal protein S10-like OS=Homo sapiens OX=9606 GN=RPS10P5 PE=5 SV=1 4.53 2822.8 - 1.00E+06 - - - -0.6776 - 2.056 0.368 - 199.8 1 2 0 -0.001 14 0 0 0 1.70E+07 1.23E+07 - - - 4.558 0.9998 221125_WJC_METTL3_EV_vs_WT_F03.15417.15417.3 0.00793 16/48 R.LMVHTVATFNSIK[136.11].E "sp|Q13813|SPTN1_HUMAN,tr|A0A0D9SF54|A0A0D9SF54_HUMAN,tr|A0A0D9SGF6|A0A0D9SGF6_HUMAN" 3 1467.7999 1.3 30938 15417 3 1467.799971 490.2739 "Spectrin alpha chain, non-erythrocytic 1 OS=Homo sapiens OX=9606 GN=SPTAN1 PE=1 SV=3" 8.76 2822.9 - 997282 - - - 0.0341 - 2.377 0.325 - 317.1 1 2 0 0.0001 13 0 0 0 2.19E+07 1.69E+07 - - - 4.511 0.9979 221125_WJC_METTL3_EV_vs_WT_F03.15419.15419.3 0.0578 Nov-36 K.YDGHLPIEIK.A "sp|P43490|NAMPT_HUMAN,tr|A0A7P0T862|A0A7P0T862_HUMAN,tr|A0A7P0TB17|A0A7P0TB17_HUMAN,tr|B7Z8W6|B7Z8W6_HUMAN,tr|A0A7P0T931|A0A7P0T931_HUMAN,tr|A0A7P0TAI8|A0A7P0TAI8_HUMAN,tr|A0A7P0T8L3|A0A7P0T8L3_HUMAN,tr|A0A7P0T941|A0A7P0T941_HUMAN,tr|A0A7P0T9F0|A0A7P0T9F0_HUMAN,tr|A0A7P0T973|A0A7P0T973_HUMAN,tr|A0A7P0T895|A0A7P0T895_HUMAN,tr|A0A7P0TBB7|A0A7P0TBB7_HUMAN,tr|A0A7P0TA73|A0A7P0TA73_HUMAN,tr|A0A0C4DFS8|A0A0C4DFS8_HUMAN,tr|A0A7P0Z4N0|A0A7P0Z4N0_HUMAN,tr|A0A7P0TAS5|A0A7P0TAS5_HUMAN,tr|A0A7P0T9I9|A0A7P0T9I9_HUMAN,tr|A0A7P0T8Z3|A0A7P0T8Z3_HUMAN,tr|A0A7P0T8R4|A0A7P0T8R4_HUMAN,tr|A0A7P0Z466|A0A7P0Z466_HUMAN,tr|A0A7P0T8D2|A0A7P0T8D2_HUMAN" 21 1183.6237 2.04 30940 15419 3 1183.623997 395.5485 Nicotinamide phosphoribosyltransferase OS=Homo sapiens OX=9606 GN=NAMPT PE=1 SV=1 5.32 2823.1 - 731741 - - - 0.2306 - 1.618 0.257 - 98.7 1 2 0 0.0003 10 0 0 0 1.33E+07 6.51E+06 - - - 2.8105 0.9993 221125_WJC_METTL3_EV_vs_WT_F03.15423.15423.3 0.00549 Dec-44 K.LSVISVEDPPQR.T sp|P38117|ETFB_HUMAN 1 1338.7143 2.11 30943 15423 3 1338.714056 447.2454 Electron transfer flavoprotein subunit beta OS=Homo sapiens OX=9606 GN=ETFB PE=1 SV=3 4.37 2823.6 - 2.19E+06 - - - -0.2047 - 1.822 0.305 - 203.6 1 2 0 -0.0003 12 0 0 0 2.55E+07 1.21E+07 - - - 3.6033 1 221125_WJC_METTL3_EV_vs_WT_F03.15425.15425.2 2.41E-08 14/22 K.VTFSC[160.03]AAGFGQR.H "sp|Q14203|DCTN1_HUMAN,tr|A0A804CDA6|A0A804CDA6_HUMAN,tr|E7EX90|E7EX90_HUMAN,tr|A0A7P0Z4C3|A0A7P0Z4C3_HUMAN,tr|E7EWF7|E7EWF7_HUMAN" 5 1299.603 1.95 30944 15425 2 1299.601072 650.8088 Dynactin subunit 1 OS=Homo sapiens OX=9606 GN=DCTN1 PE=1 SV=3 8.22 2823.8 - 2.47E+06 - - - -1.4881 - 2.547 0.621 - 708.6 1 2 0 -0.0019 12 0 0 0 1.68E+08 8.62E+07 - - - 6.087 0.9995 221125_WJC_METTL3_EV_vs_WT_F03.15426.15426.2 0.000381 20-Oct K.AGPNASIISLK[136.11].S sp|Q9H0A0|NAT10_HUMAN 1 1077.6274 0.82 30945 15426 2 1077.628063 539.821 RNA cytidine acetyltransferase OS=Homo sapiens OX=9606 GN=NAT10 PE=1 SV=2 8.8 2823.9 - 1.81E+06 - - - 0.6533 - 1.896 0.329 - 290.4 1 2 0 0.0007 11 0 0 0 3.61E+07 4.41E+07 - - - 3.2014 0.9997 221125_WJC_METTL3_EV_vs_WT_F03.15430.15430.3 0.00697 15/36 R.SLHDAIMIVR.R sp|Q99832|TCPH_HUMAN 1 1153.6278 0.16 30949 15430 3 1153.627602 385.5499 T-complex protein 1 subunit eta OS=Homo sapiens OX=9606 GN=CCT7 PE=1 SV=2 6.46 2824.1 - 2.06E+06 - - - -0.1404 - 2.31 0.288 - 384.9 1 2 0 -0.0002 10 0 0 0 9.55E+07 5.86E+08 - - - 4.196 0.9518 221125_WJC_METTL3_EV_vs_WT_F03.15431.15431.3 0.0835 Nov-56 R.VILVQEAGK[136.11]QEELIK[136.11].A "sp|Q9H8V3|ECT2_HUMAN,tr|C9JDV9|C9JDV9_HUMAN,tr|C9J1C4|C9J1C4_HUMAN,tr|C9JDB4|C9JDB4_HUMAN,tr|C9J0L6|C9J0L6_HUMAN,tr|C9JTI2|C9JTI2_HUMAN" 6 1712.0055 1.26 30950 15431 3 1712.004478 571.6758 Protein ECT2 OS=Homo sapiens OX=9606 GN=ECT2 PE=1 SV=4 4.79 2824.2 - 1.48E+06 - - - -0.5894 - 1.665 0.169 - 88.2 1 2 1 -0.001 15 0 0 0 1.72E+07 1.36E+07 - - - 1.7542 0.9999 221125_WJC_METTL3_EV_vs_WT_F03.15432.15432.3 9.49E-05 14/48 K.EMNPALGIDC[160.03]LHK.G "sp|P48643|TCPE_HUMAN,tr|E9PCA1|E9PCA1_HUMAN,tr|B7ZAR1|B7ZAR1_HUMAN,tr|E7ENZ3|E7ENZ3_HUMAN" 4 1496.7116 0.74 30951 15432 3 1496.710589 499.9111 T-complex protein 1 subunit epsilon OS=Homo sapiens OX=9606 GN=CCT5 PE=1 SV=1 5.32 2824.3 - 1.18E+06 - - - -0.6554 - 2.404 0.412 - 235.5 1 2 0 -0.001 13 0 0 0 1.20E+07 1.62E+07 - - - 5.5113 0.9995 221125_WJC_METTL3_EV_vs_WT_F03.15435.15435.3 6.26E-05 13/44 R.LQFIADHC[160.03]PTLR[166.11].V "sp|Q13098|CSN1_HUMAN,tr|J3QLE8|J3QLE8_HUMAN,tr|J3KSA5|J3KSA5_HUMAN,tr|J3QS88|J3QS88_HUMAN,tr|A0A096LP07|A0A096LP07_HUMAN,tr|A8K070|A8K070_HUMAN,tr|J3KRJ4|J3KRJ4_HUMAN,tr|J3KRE8|J3KRE8_HUMAN,tr|J3KTB0|J3KTB0_HUMAN,tr|J3QL53|J3QL53_HUMAN,tr|C9JFE4|C9JFE4_HUMAN,tr|A0A096LPJ3|A0A096LPJ3_HUMAN,tr|J3QLT0|J3QLT0_HUMAN,tr|J3QS84|J3QS84_HUMAN" 14 1479.7532 0.71 30954 15435 3 1479.757538 494.2583 COP9 signalosome complex subunit 1 OS=Homo sapiens OX=9606 GN=GPS1 PE=1 SV=4 6.74 2824.6 - 689526 - - - 2.939 - 2.554 0.34 - 274.4 1 2 0 0.0043 12 0 0 0 4.54E+06 6.38E+06 - - - 4.9285 0.9587 221125_WJC_METTL3_EV_vs_WT_F03.15441.15441.2 0.00292 16-Aug R.SIFQHIQSA.Q "sp|Q9Y2W1|TR150_HUMAN,tr|A0A3B3ITZ9|A0A3B3ITZ9_HUMAN" 2 1029.5243 - 30958 15441 2 1029.523842 515.7694 Thyroid hormone receptor-associated protein 3 OS=Homo sapiens OX=9606 GN=THRAP3 PE=1 SV=2 6.46 2825.4 - 2.11E+07 - - - -0.4876 - 1.213 0.419 - 99.7 1 1 0 -0.0005 9 0 0 0 - - - - - 2.6942 0.9997 221125_WJC_METTL3_EV_vs_WT_F03.15442.15442.2 2.43E-06 22-Nov R.AEAGDNLGALVR.G sp|P49411|EFTU_HUMAN 1 1184.6149 1.55 30959 15442 2 1184.618029 593.3148 "Elongation factor Tu, mitochondrial OS=Homo sapiens OX=9606 GN=TUFM PE=1 SV=2" 4.37 2825.4 - 4.30E+06 - - - 2.5992 - 2.428 0.54 - 497.1 1 2 0 0.0031 12 0 0 0 4.89E+08 3.15E+08 - - - 5.3625 1 221125_WJC_METTL3_EV_vs_WT_F03.15443.15443.2 4.70E-07 14/22 K.VTFSC[160.03]AAGFGQR[166.11].H "sp|Q14203|DCTN1_HUMAN,tr|A0A804CDA6|A0A804CDA6_HUMAN,tr|E7EX90|E7EX90_HUMAN,tr|A0A7P0Z4C3|A0A7P0Z4C3_HUMAN,tr|E7EWF7|E7EWF7_HUMAN" 5 1309.6113 1.95 30960 15443 2 1309.608795 655.8129 Dynactin subunit 1 OS=Homo sapiens OX=9606 GN=DCTN1 PE=1 SV=3 8.22 2825.5 - 3.73E+06 - - - -1.8945 - 2.537 0.595 - 741.7 1 2 0 -0.0025 12 0 0 0 1.68E+08 8.62E+07 - - - 5.8845 0.9994 221125_WJC_METTL3_EV_vs_WT_F03.15447.15447.2 0.000173 20-Nov K.QSEQELAYLER.R "sp|P78332|RBM6_HUMAN,tr|E9PGM9|E9PGM9_HUMAN" 2 1364.6572 0.56 30964 15447 2 1364.652733 683.3359 RNA-binding protein 6 OS=Homo sapiens OX=9606 GN=RBM6 PE=1 SV=5 4.25 2825.9 - 647242 - - - -3.2799 - 2.557 0.474 - 673.4 1 2 0 -0.0045 11 0 0 0 1.17E+07 2.09E+07 - - - 5.0803 0.9999 221125_WJC_METTL3_EV_vs_WT_F03.15448.15448.3 6.36E-05 Dec-44 K.VTFSC[160.03]AAGFGQR.H "sp|Q14203|DCTN1_HUMAN,tr|A0A804CDA6|A0A804CDA6_HUMAN,tr|E7EX90|E7EX90_HUMAN,tr|A0A7P0Z4C3|A0A7P0Z4C3_HUMAN,tr|E7EWF7|E7EWF7_HUMAN" 5 1299.603 1.65 30965 15448 3 1299.601337 434.2083 Dynactin subunit 1 OS=Homo sapiens OX=9606 GN=DCTN1 PE=1 SV=3 8.22 2826 - 433831 - - - -1.2842 - 2.161 0.48 - 154.9 1 2 0 -0.0017 12 0 0 0 9.31E+06 5.65E+06 - - - 6.027 1 221125_WJC_METTL3_EV_vs_WT_F03.15451.15451.2 1.70E-08 14/26 K.AEAGAGSATEFQFR[166.11].G "sp|Q9NQ39|RS10L_HUMAN,sp|P46783|RS10_HUMAN" 2 1450.6716 1.36 30966 15451 2 1450.669688 726.3431 Putative 40S ribosomal protein S10-like OS=Homo sapiens OX=9606 GN=RPS10P5 PE=5 SV=1 4.53 2826.4 - 9.16E+06 - - - -1.3366 - 3.344 0.55 - 783.7 1 2 0 -0.0019 14 0 0 0 2.32E+08 1.71E+08 - - - 6.132 0.999 221125_WJC_METTL3_EV_vs_WT_F03.15453.15453.2 0.0608 18-Oct K.LQQLPADFGR.L sp|Q96AG4|LRC59_HUMAN 1 1143.6037 1.21 30968 15453 2 1143.601552 572.8091 Leucine-rich repeat-containing protein 59 OS=Homo sapiens OX=9606 GN=LRRC59 PE=1 SV=1 5.84 2826.5 - 4.25E+06 - - - -1.8407 - 2.025 0.265 - 316.6 1 2 0 -0.0021 10 0 0 0 2.67E+08 2.21E+08 - - - 2.9671 0.9999 221125_WJC_METTL3_EV_vs_WT_F03.15454.15454.3 3.92E-05 14/44 K.YYVTIIDAPGHR[166.11].D "sp|P68104|EF1A1_HUMAN,sp|Q5VTE0|EF1A3_HUMAN,tr|A0A7I2V659|A0A7I2V659_HUMAN,tr|A0A7I2V3H3|A0A7I2V3H3_HUMAN,tr|Q5JR01|Q5JR01_HUMAN,tr|A0A7I2V5N4|A0A7I2V5N4_HUMAN,tr|A0A087WVQ9|A0A087WVQ9_HUMAN,tr|A6PW80|A6PW80_HUMAN,tr|A0A087WV01|A0A087WV01_HUMAN" 9 1413.728 0.41 30969 15454 3 1413.726302 472.2499 Elongation factor 1-alpha 1 OS=Homo sapiens OX=9606 GN=EEF1A1 PE=1 SV=1 6.74 2826.5 - 2.79E+06 - - - -1.2152 - 2.24 0.443 - 203 1 2 0 -0.0017 12 0 0 0 6.62E+08 1.61E+09 - - - 5.714 0.9999 221125_WJC_METTL3_EV_vs_WT_F03.15457.15457.3 3.82E-05 13/44 K.YYVTIIDAPGHR.D "sp|P68104|EF1A1_HUMAN,sp|Q5VTE0|EF1A3_HUMAN,tr|A0A7I2V659|A0A7I2V659_HUMAN,tr|A0A7I2V3H3|A0A7I2V3H3_HUMAN,tr|Q5JR01|Q5JR01_HUMAN,tr|A0A7I2V5N4|A0A7I2V5N4_HUMAN,tr|A0A087WVQ9|A0A087WVQ9_HUMAN,tr|A6PW80|A6PW80_HUMAN,tr|A0A087WV01|A0A087WV01_HUMAN" 9 1403.7197 0.41 30972 15457 3 1403.721954 468.9139 Elongation factor 1-alpha 1 OS=Homo sapiens OX=9606 GN=EEF1A1 PE=1 SV=1 6.74 2826.8 - 983905 - - - 1.5701 - 2.252 0.454 - 139 1 2 0 0.0022 12 0 0 0 6.62E+08 1.61E+09 - - - 5.8513 0.9999 221125_WJC_METTL3_EV_vs_WT_F03.15458.15458.2 0.00698 18-Nov K.C[160.03]PTLEQYAMR.A "sp|P48643|TCPE_HUMAN,tr|E9PCA1|E9PCA1_HUMAN,tr|B7ZAR1|B7ZAR1_HUMAN,tr|E7ENZ3|E7ENZ3_HUMAN" 4 1267.5689 0.67 30973 15458 2 1267.57002 634.7917 T-complex protein 1 subunit epsilon OS=Homo sapiens OX=9606 GN=CCT5 PE=1 SV=1 5.99 2827 - 653890 - - - 0.8615 - 2.361 0.511 - 566.8 1 2 0 0.0011 10 0 0 0 3.62E+07 5.37E+07 - - - 5.2129 0.9997 221125_WJC_METTL3_EV_vs_WT_F03.15463.15463.2 2.28E-06 18-Oct K.C[160.03]PTLEQYAMR[166.11].A "sp|P48643|TCPE_HUMAN,tr|E9PCA1|E9PCA1_HUMAN,tr|B7ZAR1|B7ZAR1_HUMAN,tr|E7ENZ3|E7ENZ3_HUMAN" 4 1277.5772 0.67 30976 15463 2 1277.577165 639.7959 T-complex protein 1 subunit epsilon OS=Homo sapiens OX=9606 GN=CCT5 PE=1 SV=1 5.99 2827.6 - 1.27E+06 - - - -0.0258 - 2.146 0.349 - 387.8 1 2 0 0 10 0 0 0 3.62E+07 5.38E+07 - - - 3.7502 0.9999 221125_WJC_METTL3_EV_vs_WT_F03.15464.15464.2 0.00279 17/24 K.TALEMVQAAGTDR[166.11].H "sp|P0DPB6|RPAC2_HUMAN,tr|A0A0R4J2F3|A0A0R4J2F3_HUMAN" 2 1371.6692 0.1 30977 15464 2 1371.668579 686.8419 DNA-directed RNA polymerases I and III subunit RPAC2 OS=Homo sapiens OX=9606 GN=POLR1D PE=1 SV=1 4.37 2827.7 - 2.21E+06 - - - -0.4411 - 3.165 0.449 - 1244.6 1 2 0 -0.0006 13 0 0 0 3.52E+06 3.69E+07 - - - 5.3142 0.8764 221125_WJC_METTL3_EV_vs_WT_F03.15465.15465.3 0.294 13/44 R.YIATITDK[136.11]ELLK[136.11].K "sp|Q8IWZ3|ANKH1_HUMAN,tr|E9PDP5|E9PDP5_HUMAN,tr|H3BLS9|H3BLS9_HUMAN,tr|H0Y4P6|H0Y4P6_HUMAN,tr|H7C2F5|H7C2F5_HUMAN" 5 1422.8305 0.81 30978 15465 3 1422.828898 475.2841 Ankyrin repeat and KH domain-containing protein 1 OS=Homo sapiens OX=9606 GN=ANKHD1 PE=1 SV=1 6.07 2827.9 - 1.26E+06 - - - -1.1133 - 1.554 0.128 - 106.2 1 2 1 -0.0016 12 0 0 0 1.57E+07 1.94E+07 - - - 1.1886 0.9993 221125_WJC_METTL3_EV_vs_WT_F03.15466.15466.3 0.00114 15/56 R.VILVQEAGKQEELIK.A "sp|Q9H8V3|ECT2_HUMAN,tr|C9JDV9|C9JDV9_HUMAN,tr|C9J1C4|C9J1C4_HUMAN,tr|C9JDB4|C9JDB4_HUMAN,tr|C9J0L6|C9J0L6_HUMAN,tr|C9JTI2|C9JTI2_HUMAN" 6 1695.9771 1.27 30979 15466 3 1695.975039 566.333 Protein ECT2 OS=Homo sapiens OX=9606 GN=ECT2 PE=1 SV=4 4.79 2828 - 1.12E+06 - - - -1.2076 - 2.03 0.401 - 192.2 1 2 1 -0.002 15 0 0 0 1.73E+07 1.36E+07 - - - 4.8577 0.9999 221125_WJC_METTL3_EV_vs_WT_F03.15467.15467.2 2.93E-06 22-Dec K.YYVTIIDAPGHR[166.11].D "sp|P68104|EF1A1_HUMAN,sp|Q5VTE0|EF1A3_HUMAN,tr|A0A7I2V659|A0A7I2V659_HUMAN,tr|A0A7I2V3H3|A0A7I2V3H3_HUMAN,tr|Q5JR01|Q5JR01_HUMAN,tr|A0A7I2V5N4|A0A7I2V5N4_HUMAN,tr|A0A087WVQ9|A0A087WVQ9_HUMAN,tr|A6PW80|A6PW80_HUMAN,tr|A0A087WV01|A0A087WV01_HUMAN" 9 1413.728 0.43 30980 15467 2 1413.726086 707.8713 Elongation factor 1-alpha 1 OS=Homo sapiens OX=9606 GN=EEF1A1 PE=1 SV=1 6.74 2828.1 - 778440 - - - -1.368 - 2.218 0.56 - 505.4 1 2 0 -0.0019 12 0 0 0 7.25E+07 1.69E+08 - - - 5.2726 0.9992 221125_WJC_METTL3_EV_vs_WT_F03.15469.15469.2 3.66E-05 28-Nov K.LLQSIGQAPESISEK[136.11].E sp|Q13564|ULA1_HUMAN 1 1606.8658 1.02 30982 15469 2 1606.86098 804.4402 NEDD8-activating enzyme E1 regulatory subunit OS=Homo sapiens OX=9606 GN=NAE1 PE=1 SV=1 4.53 2828.4 - 514275 - - - -2.9698 - 2.362 0.419 - 382.9 1 2 0 -0.0048 15 0 0 0 8.16E+06 8.01E+06 - - - 4.2474 0.9998 221125_WJC_METTL3_EV_vs_WT_F03.15471.15471.2 0.000603 22-Oct K.LSVISVEDPPQR.T sp|P38117|ETFB_HUMAN 1 1338.7143 1.72 30983 15471 2 1338.712908 670.3644 Electron transfer flavoprotein subunit beta OS=Homo sapiens OX=9606 GN=ETFB PE=1 SV=3 4.37 2828.6 - 6.42E+06 - - - -1.0622 - 1.951 0.443 - 228.8 1 2 0 -0.0014 12 0 0 0 2.35E+08 1.36E+08 - - - 4.0711 0.9999 221125_WJC_METTL3_EV_vs_WT_F03.15473.15473.2 1.32E-05 18-Dec R.SLHDAIMIVR[166.11].R sp|Q99832|TCPH_HUMAN 1 1163.636 0 30984 15473 2 1163.635191 582.8253 T-complex protein 1 subunit eta OS=Homo sapiens OX=9606 GN=CCT7 PE=1 SV=2 6.46 2828.8 - 1.30E+07 - - - -0.7245 - 2.146 0.568 - 452.3 1 2 0 -0.0008 10 0 0 0 2.46E+05 1.83E+08 - - - 5.3674 0.9998 221125_WJC_METTL3_EV_vs_WT_F03.15474.15474.2 0.000317 20-Dec R.ETQALILAPTR[166.11].E sp|P38919|IF4A3_HUMAN 1 1221.6957 1.97 30985 15474 2 1221.693541 611.8551 Eukaryotic initiation factor 4A-III OS=Homo sapiens OX=9606 GN=EIF4A3 PE=1 SV=4 6.1 2828.8 - 6.00E+06 - - - -1.732 - 2.133 0.516 - 579.9 1 2 0 -0.0021 11 0 0 0 2.02E+08 1.03E+08 - - - 4.9008 0.9991 221125_WJC_METTL3_EV_vs_WT_F03.15475.15475.2 0.329 18-Oct K.LQQLPADFGR[166.11].L sp|Q96AG4|LRC59_HUMAN 1 1153.6119 1.21 30986 15475 2 1153.611865 577.8132 Leucine-rich repeat-containing protein 59 OS=Homo sapiens OX=9606 GN=LRRC59 PE=1 SV=1 5.84 2828.9 - 1.09E+07 - - - -0.0537 - 1.825 0.229 - 472.4 1 2 0 -0.0001 10 0 0 0 2.71E+08 2.23E+08 - - - 2.4116 0.9239 221125_WJC_METTL3_EV_vs_WT_F03.15477.15477.2 0.0303 14-Aug A.VEFNFGQK[136.11].E "sp|Q00839|HNRPU_HUMAN,tr|A0A1W2PQL0|A0A1W2PQL0_HUMAN,tr|A0A1W2PPL4|A0A1W2PPL4_HUMAN,tr|A0A1W2PQ74|A0A1W2PQ74_HUMAN,tr|Q5RI18|Q5RI18_HUMAN,tr|A0A1W2PP35|A0A1W2PP35_HUMAN,tr|A0A1W2PPS1|A0A1W2PPS1_HUMAN,tr|A0A1W2PRZ7|A0A1W2PRZ7_HUMAN,tr|A0A1W2PPH7|A0A1W2PPH7_HUMAN,tr|A0A1W2PP34|A0A1W2PP34_HUMAN,tr|A0A1X7SBS1|A0A1X7SBS1_HUMAN" 11 975.4905 1.36 30988 15477 2 975.488409 488.7525 Heterogeneous nuclear ribonucleoprotein U OS=Homo sapiens OX=9606 GN=HNRNPU PE=1 SV=6 5.97 2829 - 2.28E+06 - - - -2.1753 - 1.596 0.333 - 209.2 1 1 0 -0.0021 8 0 0 0 4.18E+07 3.07E+07 - - - 2.9098 0.9996 221125_WJC_METTL3_EV_vs_WT_F03.15478.15478.2 0.000293 16-Sep R.GDFC[160.03]IEVGK.N "sp|Q13232|NDK3_HUMAN,tr|H3BPR2|H3BPR2_HUMAN" 2 1023.4695 0.64 30989 15478 2 1023.46829 512.742 Nucleoside diphosphate kinase 3 OS=Homo sapiens OX=9606 GN=NME3 PE=1 SV=2 4.37 2829.1 - 1.74E+06 - - - -1.2135 - 1.71 0.385 - 211 1 2 0 -0.0012 9 0 0 0 2.23E+07 3.47E+07 - - - 3.4363 0.9996 221125_WJC_METTL3_EV_vs_WT_F03.15479.15479.2 1.76E-05 20-Nov K.STYEQVDLIGK[136.11].K sp|Q9NR30|DDX21_HUMAN 1 1259.6489 4.86 30990 15479 2 1259.64675 630.8317 Nucleolar RNA helicase 2 OS=Homo sapiens OX=9606 GN=DDX21 PE=1 SV=5 4.37 2829.2 - 1.17E+06 - - - -1.6933 - 1.861 0.451 - 259.2 1 2 0 -0.0021 11 0 0 0 4.18E+07 8.60E+06 - - - 4.0517 1 221125_WJC_METTL3_EV_vs_WT_F03.15480.15480.2 2.37E-06 13/22 K.DLGGFDEDAEPR.R "sp|Q9BRK5|CAB45_HUMAN,tr|A0A5F9UJX7|A0A5F9UJX7_HUMAN,tr|A0A5F9UP49|A0A5F9UP49_HUMAN,tr|G3V1E2|G3V1E2_HUMAN,tr|H0Y3T6|H0Y3T6_HUMAN" 5 1319.563 3.95 30991 15480 2 1319.562541 660.7888 45 kDa calcium-binding protein OS=Homo sapiens OX=9606 GN=SDF4 PE=1 SV=1 3.77 2829.3 - 1.13E+06 - - - -0.3281 - 2.578 0.648 - 460.3 1 2 0 -0.0004 12 0 0 0 1.59E+07 4.03E+06 - - - 6.3187 0.9997 221125_WJC_METTL3_EV_vs_WT_F03.15485.15485.2 0.00924 18-Nov R.ISGLIYEETR.G sp|P62805|H4_HUMAN 1 1179.6136 1.18 30995 15485 2 1179.613075 590.8141 Histone H4 OS=Homo sapiens OX=9606 GN=H4C1 PE=1 SV=2 4.53 2829.9 - 773394 - - - -0.4052 - 2.331 0.306 - 394.6 1 2 0 -0.0005 10 0 0 0 1.42E+08 1.20E+08 - - - 3.6632 0.9248 221125_WJC_METTL3_EV_vs_WT_F03.15487.15487.2 5.80E-05 20-Dec T.ANVSVVDLTC[160.03]R.L "sp|P04406|G3P_HUMAN,tr|E7EUT5|E7EUT5_HUMAN" 2 1232.6183 0.84 30996 15487 2 1232.615002 617.3164 Glyceraldehyde-3-phosphate dehydrogenase OS=Homo sapiens OX=9606 GN=GAPDH PE=1 SV=3 5.87 2830.2 - 2.73E+06 - - - -2.6926 - 2.235 0.284 - 576 1 1 0 -0.0033 11 0 0 0 4.84E+07 5.75E+07 - - - 3.3132 0.9995 221125_WJC_METTL3_EV_vs_WT_F03.15490.15490.2 0.362 20-Dec K.LALEQQQLIC[160.03]K.Q "sp|Q8IWX8|CHERP_HUMAN,tr|J3QK89|J3QK89_HUMAN" 2 1342.7279 0.96 30999 15490 2 1342.725921 672.3712 Calcium homeostasis endoplasmic reticulum protein OS=Homo sapiens OX=9606 GN=CHERP PE=1 SV=3 5.99 2830.4 - 2.93E+06 - - - -1.453 - 2.174 0.322 - 371 1 2 0 -0.002 11 0 0 0 4.24E+07 4.40E+07 - - - 3.5195 0.87 221125_WJC_METTL3_EV_vs_WT_F03.15491.15491.2 0.0226 14-Jul A.VEFNFGQK.E "sp|Q00839|HNRPU_HUMAN,tr|A0A1W2PQL0|A0A1W2PQL0_HUMAN,tr|A0A1W2PPL4|A0A1W2PPL4_HUMAN,tr|A0A1W2PQ74|A0A1W2PQ74_HUMAN,tr|Q5RI18|Q5RI18_HUMAN,tr|A0A1W2PP35|A0A1W2PP35_HUMAN,tr|A0A1W2PPS1|A0A1W2PPS1_HUMAN,tr|A0A1W2PRZ7|A0A1W2PRZ7_HUMAN,tr|A0A1W2PPH7|A0A1W2PPH7_HUMAN,tr|A0A1W2PP34|A0A1W2PP34_HUMAN,tr|A0A1X7SBS1|A0A1X7SBS1_HUMAN" 11 967.4763 0.91 31000 15491 2 967.474317 484.7454 Heterogeneous nuclear ribonucleoprotein U OS=Homo sapiens OX=9606 GN=HNRNPU PE=1 SV=6 5.97 2830.5 - 2.57E+06 - - - -2.0817 - 1.392 0.306 - 151.7 1 1 0 -0.002 8 0 0 0 2.54E+07 2.80E+07 - - - 2.298 0.9993 221125_WJC_METTL3_EV_vs_WT_F03.15494.15494.2 0.000163 13/28 K.LLQSIGQAPESISEK.E sp|Q13564|ULA1_HUMAN 1 1598.8516 1.02 31003 15494 2 1598.856836 800.4331 NEDD8-activating enzyme E1 regulatory subunit OS=Homo sapiens OX=9606 GN=NAE1 PE=1 SV=1 4.53 2830.8 - 785742 - - - 3.3049 - 2.614 0.476 - 487.6 1 2 0 0.0053 15 0 0 0 8.16E+06 8.01E+06 - - - 4.9174 0.9997 221125_WJC_METTL3_EV_vs_WT_F03.15496.15496.2 1.88E-07 24-Nov K.LILYQEAAATNGR.V sp|Q9BTX1|NDC1_HUMAN 1 1418.7518 3.23 31005 15496 2 1418.747763 710.3832 Nucleoporin NDC1 OS=Homo sapiens OX=9606 GN=NDC1 PE=1 SV=2 6 2831 - 622291 - - - -2.83 - 2.535 0.554 - 461 1 2 0 -0.004 13 0 0 0 1.22E+07 3.78E+06 - - - 5.519 1 221125_WJC_METTL3_EV_vs_WT_F03.15498.15498.2 7.00E-09 15/24 K.C[160.03]PLSGAC[160.03]YSPEFK[136.11].G "sp|P53621|COPA_HUMAN,tr|A0A3B3ISC6|A0A3B3ISC6_HUMAN,tr|A0A3B3IS84|A0A3B3IS84_HUMAN,tr|A0A3B3ITI7|A0A3B3ITI7_HUMAN,tr|A0A3B3IT15|A0A3B3IT15_HUMAN" 5 1522.6676 0.2 31007 15498 2 1522.667526 762.3411 Coatomer subunit alpha OS=Homo sapiens OX=9606 GN=COPA PE=1 SV=2 5.99 2831.3 - 572214 - - - -0.0401 - 2.856 0.622 - 905.1 1 2 0 -0.0001 13 0 0 0 2.26E+06 1.15E+07 - - - 6.3284 0.9999 221125_WJC_METTL3_EV_vs_WT_F03.15502.15502.2 7.82E-06 22-Dec R.AEAGDNLGALVR[166.11].G sp|P49411|EFTU_HUMAN 1 1194.6232 1.56 31009 15502 2 1194.622641 598.3189 "Elongation factor Tu, mitochondrial OS=Homo sapiens OX=9606 GN=TUFM PE=1 SV=2" 4.37 2831.8 - 1.83E+07 - - - -0.4847 - 2.415 0.545 - 645.5 1 2 0 -0.0006 12 0 0 0 4.91E+08 3.15E+08 - - - 5.3861 1 221125_WJC_METTL3_EV_vs_WT_F03.15505.15505.2 5.83E-07 14/24 K.QSLEASLAETEGR.Y "sp|P13645|K1C10_HUMAN,tr|A0A1B0GVI3|A0A1B0GVI3_HUMAN" 2 1389.6736 999 31012 15505 2 1389.672743 695.8441 "Keratin, type I cytoskeletal 10 OS=Homo sapiens OX=9606 GN=KRT10 PE=1 SV=6" 4.25 2832 - 3.29E+06 - - - -0.6073 - 2.939 0.556 - 765.3 1 2 0 -0.0008 13 0 0 0 6.86E+09 0.00E+00 - - - 5.9142 0.9999 221125_WJC_METTL3_EV_vs_WT_F03.15506.15506.2 8.14E-06 22-Dec K.YYVTIIDAPGHR.D "sp|P68104|EF1A1_HUMAN,sp|Q5VTE0|EF1A3_HUMAN,tr|A0A7I2V659|A0A7I2V659_HUMAN,tr|A0A7I2V3H3|A0A7I2V3H3_HUMAN,tr|Q5JR01|Q5JR01_HUMAN,tr|A0A7I2V5N4|A0A7I2V5N4_HUMAN,tr|A0A087WVQ9|A0A087WVQ9_HUMAN,tr|A6PW80|A6PW80_HUMAN,tr|A0A087WV01|A0A087WV01_HUMAN" 9 1403.7197 0.4 31013 15506 2 1403.719754 702.8672 Elongation factor 1-alpha 1 OS=Homo sapiens OX=9606 GN=EEF1A1 PE=1 SV=1 6.74 2832.1 - 2.80E+06 - - - 0.0028 - 2.262 0.505 - 454.1 1 2 0 0 12 0 0 0 6.67E+07 1.69E+08 - - - 4.9186 1 221125_WJC_METTL3_EV_vs_WT_F03.15510.15510.3 0.000261 Dec-44 R.LIDLHSPSEIVK.Q "sp|P60866|RS20_HUMAN,tr|A0A7P0S5H5|A0A7P0S5H5_HUMAN,tr|G3XAN0|G3XAN0_HUMAN" 3 1349.7555 1.33 31017 15510 3 1349.755166 450.9258 40S ribosomal protein S20 OS=Homo sapiens OX=9606 GN=RPS20 PE=1 SV=1 5.32 2832.4 - 1.30E+06 - - - -0.223 - 2.326 0.452 - 221.9 1 2 0 -0.0003 12 0 0 0 7.73E+09 5.79E+09 - - - 5.9191 0.9996 221125_WJC_METTL3_EV_vs_WT_F03.15511.15511.3 0.00779 Aug-36 R.LVNHFVEEFK[136.11].R "sp|P0DMV8|HS71A_HUMAN,sp|P0DMV9|HS71B_HUMAN,tr|V9GZ37|V9GZ37_HUMAN,tr|A0A0G2JIW1|A0A0G2JIW1_HUMAN" 4 1268.6645 0.14 31018 15511 3 1268.662728 423.8954 Heat shock 70 kDa protein 1A OS=Homo sapiens OX=9606 GN=HSPA1A PE=1 SV=1 5.4 2832.5 - 1.09E+06 - - - -1.3755 - 2.035 0.32 - 86.9 1 2 0 -0.0017 10 0 0 0 1.55E+09 1.13E+10 - - - 4.1822 0.9996 221125_WJC_METTL3_EV_vs_WT_F03.15513.15513.2 3.70E-05 16/28 R.ASYVAPLTAQPATYR.A sp|Q96PK6|RBM14_HUMAN 1 1607.8308 1.92 31020 15513 2 1607.82631 804.9227 RNA-binding protein 14 OS=Homo sapiens OX=9606 GN=RBM14 PE=1 SV=2 8.63 2832.8 - 1.05E+06 - - - -2.7658 - 2.513 0.546 - 504.5 1 2 0 -0.0044 15 0 0 0 2.13E+09 1.11E+09 - - - 5.3379 0.9993 221125_WJC_METTL3_EV_vs_WT_F03.15516.15516.3 0.00276 16/40 R.NLPLPPPPPPR[166.11].G "sp|P61978|HNRPK_HUMAN,tr|Q5T6W2|Q5T6W2_HUMAN" 2 1203.7003 1.84 31023 15516 3 1203.696494 402.2407 Heterogeneous nuclear ribonucleoprotein K OS=Homo sapiens OX=9606 GN=HNRNPK PE=1 SV=1 9.75 2833.1 - 677617 - - - -3.2018 - 2.575 0.315 - 361 1 2 0 -0.0039 11 0 0 0 2.63E+07 1.43E+07 - - - 4.7379 0.9978 221125_WJC_METTL3_EV_vs_WT_F03.15521.15521.2 0.091 12-Jul R.VSWQDLK[136.11].D sp|Q13243|SRSF5_HUMAN 1 882.4691 0.95 31027 15521 2 882.468431 442.2418 Serine\arginine-rich splicing factor 5 OS=Homo sapiens OX=9606 GN=SRSF5 PE=1 SV=1 5.81 2833.7 - 1.70E+06 - - - -0.7218 - 1.571 0.179 - 160.9 1 2 0 -0.0006 7 0 0 0 5.62E+07 5.93E+07 - - - 1.7942 0.9999 221125_WJC_METTL3_EV_vs_WT_F03.15523.15523.3 0.00345 Dec-48 K.QSLEASLAETEGR.Y "sp|P13645|K1C10_HUMAN,tr|A0A1B0GVI3|A0A1B0GVI3_HUMAN" 2 1389.6736 570.16 31028 15523 3 1389.674899 464.2318 "Keratin, type I cytoskeletal 10 OS=Homo sapiens OX=9606 GN=KRT10 PE=1 SV=6" 4.25 2833.9 - 8.51E+06 - - - 0.9441 - 2.256 0.41 - 221.3 1 2 0 0.0013 13 0 0 0 1.59E+09 2.79E+06 - - - 5.3166 0.9989 221125_WJC_METTL3_EV_vs_WT_F03.15524.15524.2 0.0373 16-Aug K.ESSTVFELK.R "sp|Q15370|ELOB_HUMAN,tr|I3L0M9|I3L0M9_HUMAN,tr|A0A0B4J296|A0A0B4J296_HUMAN,tr|B8ZZU8|B8ZZU8_HUMAN" 4 1038.5233 1.39 31029 15524 2 1038.523438 520.2689 Elongin-B OS=Homo sapiens OX=9606 GN=ELOB PE=1 SV=1 4.53 2834 - 4.00E+06 - - - 0.0934 - 1.721 0.223 - 326.5 1 2 0 0.0001 9 0 0 0 8.76E+07 6.29E+07 - - - 2.2587 1 221125_WJC_METTL3_EV_vs_WT_F03.15525.15525.3 6.55E-06 16/56 R.ASYVAPLTAQPATYR.A sp|Q96PK6|RBM14_HUMAN 1 1607.8308 1.98 31030 15525 3 1607.830268 536.9509 RNA-binding protein 14 OS=Homo sapiens OX=9606 GN=RBM14 PE=1 SV=2 8.63 2834 - 4.09E+06 - - - -0.3041 - 2.944 0.505 - 260.7 1 2 0 -0.0005 15 0 0 0 6.86E+08 3.46E+08 - - - 6.9876 1 221125_WJC_METTL3_EV_vs_WT_F03.15526.15526.3 1.18E-07 16/56 R.ASYVAPLTAQPATYR[166.11].A sp|Q96PK6|RBM14_HUMAN 1 1617.839 1.98 31031 15526 3 1617.838343 540.287 RNA-binding protein 14 OS=Homo sapiens OX=9606 GN=RBM14 PE=1 SV=2 8.63 2834.1 - 3.05E+06 - - - -0.4228 - 2.709 0.562 - 265.7 1 2 0 -0.0007 15 0 0 0 6.86E+08 3.46E+08 - - - 7.406 1 221125_WJC_METTL3_EV_vs_WT_F03.15527.15527.3 4.36E-05 15/44 R.GFTAAGILSAHK[136.11].L "sp|Q96C36|P5CR2_HUMAN,tr|A0A087WTV6|A0A087WTV6_HUMAN,tr|J3KR12|J3KR12_HUMAN" 3 1179.6492 0.73 31032 15527 3 1179.648056 394.2237 Pyrroline-5-carboxylate reductase 2 OS=Homo sapiens OX=9606 GN=PYCR2 PE=1 SV=1 8.76 2834.1 - 1.68E+06 - - - -0.9333 - 2.392 0.458 - 202.9 1 2 0 -0.0011 12 0 0 0 1.31E+07 1.79E+07 - - - 6.0634 1 221125_WJC_METTL3_EV_vs_WT_F03.15528.15528.2 6.01E-07 18/28 K.LTADPDSEIATTSLR.V "sp|O75928|PIAS2_HUMAN,sp|O75925|PIAS1_HUMAN,tr|B4DGW0|B4DGW0_HUMAN,tr|A0A087WUY7|A0A087WUY7_HUMAN" 4 1588.7944 1.05 31033 15528 2 1588.793649 795.4045 E3 SUMO-protein ligase PIAS2 OS=Homo sapiens OX=9606 GN=PIAS2 PE=1 SV=3 4.03 2834.3 - 1.54E+06 - - - -0.4922 - 3.205 0.632 - 974.5 1 2 0 -0.0008 15 0 0 0 3.33E+07 3.18E+07 - - - 6.5722 0.9995 221125_WJC_METTL3_EV_vs_WT_F03.15530.15530.2 0.000302 20-Aug K.QVVESAYEVIK[136.11].L sp|P00338|LDHA_HUMAN 1 1271.6853 0.95 31035 15530 2 1271.686765 636.8499 L-lactate dehydrogenase A chain OS=Homo sapiens OX=9606 GN=LDHA PE=1 SV=2 4.53 2834.4 - 1.34E+06 - - - 1.1772 - 1.841 0.369 - 161 1 2 0 0.0015 11 0 0 0 1.95E+07 2.05E+07 - - - 3.417 1 221125_WJC_METTL3_EV_vs_WT_F03.15532.15532.2 3.32E-07 20-Nov K.YTGEDFDEDLR[166.11].T "sp|Q14204|DYHC1_HUMAN,tr|A0A7P0T8N2|A0A7P0T8N2_HUMAN,tr|A0A7P0T9C4|A0A7P0T9C4_HUMAN,tr|A0A7P0TBJ7|A0A7P0TBJ7_HUMAN,tr|A0A7P0T9K2|A0A7P0T9K2_HUMAN,tr|A0A2R8Y706|A0A2R8Y706_HUMAN,tr|A0A7P0T916|A0A7P0T916_HUMAN,tr|A0A7P0TB75|A0A7P0TB75_HUMAN,tr|A0A7P0T8W5|A0A7P0T8W5_HUMAN,tr|A0A7P0TAF3|A0A7P0TAF3_HUMAN,tr|A0A7P0T9F1|A0A7P0T9F1_HUMAN,tr|A0A7P0TAW9|A0A7P0TAW9_HUMAN,tr|A0A7P0TA13|A0A7P0TA13_HUMAN,tr|A0A7P0T7V5|A0A7P0T7V5_HUMAN,tr|A0A7P0T9R4|A0A7P0T9R4_HUMAN,tr|A0A2R8Y5T0|A0A2R8Y5T0_HUMAN,tr|A0A2R8YFZ7|A0A2R8YFZ7_HUMAN,tr|A0A7P0T825|A0A7P0T825_HUMAN,tr|A0A2R8Y6H2|A0A2R8Y6H2_HUMAN,tr|A0A7P0TAM4|A0A7P0TAM4_HUMAN" 20 1368.5709 0.001 31037 15532 2 1368.571829 685.2927 Cytoplasmic dynein 1 heavy chain 1 OS=Homo sapiens OX=9606 GN=DYNC1H1 PE=1 SV=5 3.77 2834.6 - 904714 - - - 0.6715 - 2.32 0.687 - 434.7 1 2 0 0.0009 11 0 0 0 0.00E+00 1.02E+07 - - - 6.3915 0.9995 221125_WJC_METTL3_EV_vs_WT_F03.15533.15533.2 0.000144 18-Oct R.SFGGEVSWDK[136.11].S "sp|O00541|PESC_HUMAN,tr|B3KXD6|B3KXD6_HUMAN,tr|B5MCF9|B5MCF9_HUMAN" 3 1118.5124 0.97 31038 15533 2 1118.510969 560.2635 Pescadillo homolog OS=Homo sapiens OX=9606 GN=PES1 PE=1 SV=1 4.37 2834.7 - 753034 - - - -1.2695 - 1.533 0.42 - 213 1 2 0 -0.0014 10 0 0 0 1.91E+07 1.98E+07 - - - 3.3352 0.9998 221125_WJC_METTL3_EV_vs_WT_F03.15534.15534.2 2.51E-05 22-Nov K.TLPADVQNYYSR[166.11].R "sp|Q99590|SCAFB_HUMAN,tr|F8VXG7|F8VXG7_HUMAN" 2 1435.6971 1 31039 15534 2 1435.699765 718.8558 Protein SCAF11 OS=Homo sapiens OX=9606 GN=SCAF11 PE=1 SV=2 5.5 2834.8 - 626951 - - - 1.8465 - 2.085 0.585 - 421.9 1 2 0 0.0027 12 0 0 0 1.69E+07 1.68E+07 - - - 5.2943 0.9994 221125_WJC_METTL3_EV_vs_WT_F03.15535.15535.2 0.000209 24-Nov R.LGGISSTEEMDLK.V "sp|O75150|BRE1B_HUMAN,tr|H3BP71|H3BP71_HUMAN,tr|H3BUL6|H3BUL6_HUMAN,tr|H3BQ99|H3BQ99_HUMAN,tr|I3L332|I3L332_HUMAN" 5 1378.665 1.04 31040 15535 2 1378.66053 690.3398 E3 ubiquitin-protein ligase BRE1B OS=Homo sapiens OX=9606 GN=RNF40 PE=1 SV=5 4.14 2835 - 578110 - - - -3.2401 - 2.171 0.519 - 383.5 1 2 0 -0.0045 13 0 0 0 7.60E+06 7.33E+06 - - - 4.8625 0.9963 221125_WJC_METTL3_EV_vs_WT_F03.15539.15539.2 0.0412 16-Aug K.ESSTVFELK[136.11].R "sp|Q15370|ELOB_HUMAN,tr|I3L0M9|I3L0M9_HUMAN,tr|A0A0B4J296|A0A0B4J296_HUMAN,tr|B8ZZU8|B8ZZU8_HUMAN" 4 1046.5375 1.36 31042 15539 2 1046.536986 524.276 Elongin-B OS=Homo sapiens OX=9606 GN=ELOB PE=1 SV=1 4.53 2835.4 - 6.78E+06 - - - -0.5303 - 1.732 0.097 - 355.2 1 2 0 -0.0006 9 0 0 0 8.55E+07 6.29E+07 - - - 1.3464 0.9995 221125_WJC_METTL3_EV_vs_WT_F03.15540.15540.2 0.00429 22-Dec K.ASGPPVSELITK[136.11].A "sp|P10412|H14_HUMAN,sp|P16403|H12_HUMAN,sp|P16402|H13_HUMAN" 3 1205.6747 0.73 31043 15540 2 1205.674439 603.8446 Histone H1.4 OS=Homo sapiens OX=9606 GN=H1-4 PE=1 SV=2 6.05 2835.4 - 5.00E+06 - - - -0.2198 - 1.779 0.33 - 420.1 1 2 0 -0.0003 12 0 0 0 7.37E+08 1.02E+09 - - - 2.994 0.989 221125_WJC_METTL3_EV_vs_WT_F03.15541.15541.2 0.0456 18-Oct Y.VTIIDAPGHR[166.11].D "sp|P68104|EF1A1_HUMAN,sp|Q5VTE0|EF1A3_HUMAN,tr|A0A7I2V659|A0A7I2V659_HUMAN,tr|A0A7I2V3H3|A0A7I2V3H3_HUMAN,tr|Q5JR01|Q5JR01_HUMAN,tr|A0A7I2V5N4|A0A7I2V5N4_HUMAN,tr|A0A087WVQ9|A0A087WVQ9_HUMAN,tr|A6PW80|A6PW80_HUMAN,tr|A0A087WV01|A0A087WV01_HUMAN" 9 1087.6014 0.58 31044 15541 2 1087.601894 544.808 Elongation factor 1-alpha 1 OS=Homo sapiens OX=9606 GN=EEF1A1 PE=1 SV=1 6.71 2835.5 - 2.31E+06 - - - 0.4882 - 2.379 0.386 - 329.4 1 1 0 0.0005 10 0 0 0 1.28E+07 2.21E+07 - - - 4.311 1 221125_WJC_METTL3_EV_vs_WT_F03.15542.15542.2 8.45E-07 14/22 K.QITQSALLAEAR[166.11].S sp|P78527|PRKDC_HUMAN 1 1309.7229 0.79 31045 15542 2 1309.728146 655.8687 DNA-dependent protein kinase catalytic subunit OS=Homo sapiens OX=9606 GN=PRKDC PE=1 SV=3 6 2835.5 - 2.16E+06 - - - 3.9795 - 2.736 0.563 - 910.3 1 2 0 0.0052 12 0 0 0 1.66E+07 2.12E+07 - - - 5.8459 0.9883 221125_WJC_METTL3_EV_vs_WT_F03.15543.15543.2 0.000121 22-Sep K.EGAAVIDVGINR[166.11].V "sp|P13995|MTDC_HUMAN,tr|A0A7I2V482|A0A7I2V482_HUMAN,tr|A0A7I2V2U6|A0A7I2V2U6_HUMAN,tr|A0A7I2YQD4|A0A7I2YQD4_HUMAN,tr|B9A062|B9A062_HUMAN" 5 1222.6545 1.48 31046 15543 2 1222.659764 612.3345 "Bifunctional methylenetetrahydrofolate dehydrogenase\cyclohydrolase, mitochondrial OS=Homo sapiens OX=9606 GN=MTHFD2 PE=1 SV=2" 4.37 2835.6 - 1.52E+06 - - - 4.289 - 2.142 0.18 - 321.2 1 2 0 0.0052 12 0 0 0 1.53E+08 1.04E+08 - - - 2.3731 0.998 221125_WJC_METTL3_EV_vs_WT_F03.15544.15544.2 0.00206 18-Sep R.GLVLSGVLHK.A sp|P29508|SPB3_HUMAN 1 1021.6284 336.87 31047 15544 2 1021.628098 511.8215 Serpin B3 OS=Homo sapiens OX=9606 GN=SERPINB3 PE=1 SV=2 8.76 2835.7 - 1.15E+06 - - - -0.3103 - 2.07 0.097 - 288 1 2 0 -0.0003 10 0 0 0 5.35E+07 1.59E+05 - - - 1.7882 0.9982 221125_WJC_METTL3_EV_vs_WT_F03.15545.15545.2 0.289 24-Oct R.VLGIQVDTDGSGR.S "sp|P33992|MCM5_HUMAN,tr|B1AHB1|B1AHB1_HUMAN" 2 1315.6732 0.8 31048 15545 2 1315.676638 658.8439 DNA replication licensing factor MCM5 OS=Homo sapiens OX=9606 GN=MCM5 PE=1 SV=5 4.21 2835.9 - 1.09E+06 - - - 2.6184 - 2.142 0.287 - 276 2 2 0 0.0034 13 0 0 0 2.46E+07 3.07E+07 - - - 2.9803 0.996 221125_WJC_METTL3_EV_vs_WT_F03.15546.15546.2 0.194 14-Jun R.HPQEQPLW.- "sp|Q16378|PROL4_HUMAN,tr|A0A0J9YXF8|A0A0J9YXF8_HUMAN" 2 1033.4981 - 31049 15546 2 1033.497256 517.7563 Proline-rich protein 4 OS=Homo sapiens OX=9606 GN=PRR4 PE=1 SV=3 5.24 2836 - 655069 - - - -0.8457 - 1.13 0.262 - 108.6 1 2 0 -0.0009 8 0 0 0 - - - - - 1.3445 0.9923 221125_WJC_METTL3_EV_vs_WT_F03.15547.15547.2 0.0174 14-Jul K.TWTTADFR[166.11].T "sp|Q9ULX6|AKP8L_HUMAN,tr|A0A7P0T9N5|A0A7P0T9N5_HUMAN,tr|A0A7P0TAD3|A0A7P0TAD3_HUMAN,tr|V9GZ50|V9GZ50_HUMAN,tr|A0A7P0TBP0|A0A7P0TBP0_HUMAN,tr|A0A7P0TAJ5|A0A7P0TAJ5_HUMAN,tr|A0A7P0TAE3|A0A7P0TAE3_HUMAN,tr|A0A7P0T847|A0A7P0T847_HUMAN" 8 1006.4748 0.93 31050 15547 2 1006.471525 504.2447 A-kinase anchor protein 8-like OS=Homo sapiens OX=9606 GN=AKAP8L PE=1 SV=4 5.5 2836.1 - 532218 - - - -3.2192 - 1.5 0.24 - 196.8 1 2 0 -0.0032 8 0 0 0 1.07E+07 1.16E+07 - - - 2.0355 0.9934 221125_WJC_METTL3_EV_vs_WT_F03.15548.15548.2 0.285 14-May K.IC[160.03]C[160.03]QFDFK[136.11].R "sp|Q16706|MA2A1_HUMAN,sp|P49641|MA2A2_HUMAN,tr|H0YNG5|H0YNG5_HUMAN,tr|H0YLB9|H0YLB9_HUMAN,tr|A0A0C4DGL1|A0A0C4DGL1_HUMAN" 5 1124.4874 0.65 31051 15548 2 1124.487392 563.251 Alpha-mannosidase 2 OS=Homo sapiens OX=9606 GN=MAN2A1 PE=1 SV=2 5.82 2836.2 - 379843 - - - -0.04 - 1.085 0.218 - 53 1 2 0 0 8 0 0 0 6.10E+06 9.36E+06 - - - 0.8972 0.9992 221125_WJC_METTL3_EV_vs_WT_F03.15551.15551.2 0.215 24-Oct R.LGGEVSC[160.03]LVAGTK.C "sp|P13804|ETFA_HUMAN,tr|J3KN60|J3KN60_HUMAN,tr|H0YKF0|H0YKF0_HUMAN,tr|H0YLU7|H0YLU7_HUMAN" 4 1289.6649 1.44 31052 15551 2 1289.661062 645.8397 "Electron transfer flavoprotein subunit alpha, mitochondrial OS=Homo sapiens OX=9606 GN=ETFA PE=1 SV=1" 5.99 2836.6 - 6.46E+06 - - - -3.0047 - 2.243 0.423 - 320.1 1 2 0 -0.0039 13 0 0 0 7.00E+07 4.87E+07 - - - 4.2373 0.9987 221125_WJC_METTL3_EV_vs_WT_F03.15552.15552.2 0.000594 22-Oct R.SIFASPESVTGK[136.11].V sp|O75940|SPF30_HUMAN 1 1229.6383 0.72 31053 15552 2 1229.642332 615.8264 Survival of motor neuron-related-splicing factor 30 OS=Homo sapiens OX=9606 GN=SMNDC1 PE=1 SV=1 5.72 2836.7 - 1.80E+06 - - - 3.2644 - 1.962 0.413 - 242.9 1 2 0 0.004 12 0 0 0 6.75E+07 9.34E+07 - - - 3.8635 0.9978 221125_WJC_METTL3_EV_vs_WT_F03.15553.15553.2 2.40E-05 20-Dec R.SIQAALDSAYK.E "sp|P82094|TMF1_HUMAN,tr|F8WF45|F8WF45_HUMAN" 2 1165.5979 1.59 31054 15553 2 1165.603773 583.8062 TATA element modulatory factor OS=Homo sapiens OX=9606 GN=TMF1 PE=1 SV=2 5.55 2836.7 - 2.88E+06 - - - 5.036 - 2.437 0.488 - 429.6 1 2 0 0.0059 11 0 0 0 1.34E+08 8.41E+07 - - - 5.0533 0.9859 221125_WJC_METTL3_EV_vs_WT_F03.15554.15554.2 0.000529 14-Jul P.QWIC[160.03]C[160.03]DIR[166.11].Y sp|Q86U44|MTA70_HUMAN 1 1159.5142 1.03 31055 15554 2 1159.513226 580.7644 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 5.82 2836.8 - 2.28E+06 - - - -0.8435 - 1.715 0.452 - 158.3 1 1 0 -0.001 8 0 0 0 2.64E+07 2.56E+07 - - - 4.006 0.9999 221125_WJC_METTL3_EV_vs_WT_F03.15558.15558.2 0.00107 20-Dec R.VEDLQTQDFVR.S sp|P0C7T5|ATX1L_HUMAN 1 1348.6623 1.8 31059 15558 2 1348.661132 675.3384 Ataxin-1-like OS=Homo sapiens OX=9606 GN=ATXN1L PE=1 SV=1 4.03 2837.2 - 959708 - - - -0.8616 - 2.429 0.475 - 704 1 2 0 -0.0012 11 0 0 0 2.97E+07 1.65E+07 - - - 4.9498 0.9997 221125_WJC_METTL3_EV_vs_WT_F03.15559.15559.2 0.0033 18-Oct K.IWDISQPGSK.S "sp|Q04726|TLE3_HUMAN,tr|A0A0D9SES8|A0A0D9SES8_HUMAN,tr|H0YL70|H0YL70_HUMAN,tr|H0YKN8|H0YKN8_HUMAN,tr|H0YKT5|H0YKT5_HUMAN,tr|H0YLI3|H0YLI3_HUMAN,tr|H0YNI7|H0YNI7_HUMAN,tr|H0YNT2|H0YNT2_HUMAN" 8 1129.5768 1.6 31060 15559 2 1129.576342 565.7957 Transducin-like enhancer protein 3 OS=Homo sapiens OX=9606 GN=TLE3 PE=1 SV=2 5.84 2837.4 - 940788 - - - -0.3824 - 1.817 0.378 - 250.4 1 2 0 -0.0004 10 0 0 0 1.08E+07 6.76E+06 - - - 3.4997 0.9998 221125_WJC_METTL3_EV_vs_WT_F03.15560.15560.2 3.33E-05 22-Oct R.FLESLPEEEQQR.V "sp|P17480|UBF1_HUMAN,tr|E9PKP7|E9PKP7_HUMAN" 2 1503.7205 1.51 31061 15560 2 1503.722791 752.8675 Nucleolar transcription factor 1 OS=Homo sapiens OX=9606 GN=UBTF PE=1 SV=1 4.09 2837.5 - 882246 - - - 1.4983 - 2.157 0.513 - 228.5 1 2 0 0.0023 12 0 0 0 5.84E+07 3.87E+07 - - - 4.8519 0.997 221125_WJC_METTL3_EV_vs_WT_F03.15561.15561.3 0.292 14/40 R.LAGIINFQRPK.D sp|O00232|PSD12_HUMAN 1 1255.7401 1.32 31062 15561 3 1255.73621 419.5873 26S proteasome non-ATPase regulatory subunit 12 OS=Homo sapiens OX=9606 GN=PSMD12 PE=1 SV=3 11 2837.6 - 852221 - - - -3.0906 - 2.098 0.257 - 280.7 1 2 0 -0.0039 11 0 0 0 4.55E+07 3.44E+07 - - - 3.5092 0.9834 221125_WJC_METTL3_EV_vs_WT_F03.15563.15563.3 1.04E-05 17/40 R.PMIHELLTEGR[166.11].R "sp|Q14974|IMB1_HUMAN,tr|J3KTM9|J3KTM9_HUMAN" 2 1304.6786 1.14 31064 15563 3 1304.674815 435.9002 Importin subunit beta-1 OS=Homo sapiens OX=9606 GN=KPNB1 PE=1 SV=2 5.41 2837.9 - 701153 - - - -2.9218 - 3.111 0.381 - 787.9 1 1 0 -0.0038 11 0 0 0 5.91E+07 5.17E+07 - - - 6.0109 1 221125_WJC_METTL3_EV_vs_WT_F03.15566.15566.2 1.11E-07 13/30 Y.ITGETVVVGGGTPSRL.- "sp|Q9BTZ2|DHRS4_HUMAN,tr|E9PFL3|E9PFL3_HUMAN,tr|A0A087WXI8|A0A087WXI8_HUMAN" 3 1541.8413 2.1 31067 15566 2 1541.844133 771.9279 Dehydrogenase\reductase SDR family member 4 OS=Homo sapiens OX=9606 GN=DHRS4 PE=1 SV=3 6 2838.3 - 365597 - - - 1.8231 - 2.66 0.58 - 438.9 1 1 0 0.0028 16 0 0 0 4.20E+06 2.00E+06 - - - 5.7293 0.9946 221125_WJC_METTL3_EV_vs_WT_F03.15569.15569.2 0.000127 18-Aug K.LDVTSVEDYK[136.11].A "sp|P48643|TCPE_HUMAN,tr|E9PCA1|E9PCA1_HUMAN,tr|B7ZAR1|B7ZAR1_HUMAN,tr|E7ENZ3|E7ENZ3_HUMAN" 4 1175.5801 0.66 31068 15569 2 1175.575446 588.7973 T-complex protein 1 subunit epsilon OS=Homo sapiens OX=9606 GN=CCT5 PE=1 SV=1 4.03 2838.6 - 8.35E+06 - - - -3.9878 - 2.12 0.234 - 209.7 1 2 0 -0.0047 10 0 0 0 5.07E+08 7.71E+08 - - - 2.8653 0.9831 221125_WJC_METTL3_EV_vs_WT_F03.15572.15572.3 0.0328 13/40 R.PMIHELLTEGR.R "sp|Q14974|IMB1_HUMAN,tr|J3KTM9|J3KTM9_HUMAN" 2 1294.6704 1.17 31071 15572 3 1294.669266 432.5641 Importin subunit beta-1 OS=Homo sapiens OX=9606 GN=KPNB1 PE=1 SV=2 5.41 2838.8 - 2.29E+06 - - - -0.8427 - 2.648 0.308 - 402.3 1 1 0 -0.0011 11 0 0 0 5.78E+07 4.94E+07 - - - 4.74 0.9999 221125_WJC_METTL3_EV_vs_WT_F03.15574.15574.2 5.14E-05 15/22 R.LIDLHSPSEIVK.Q "sp|P60866|RS20_HUMAN,tr|A0A7P0S5H5|A0A7P0S5H5_HUMAN,tr|G3XAN0|G3XAN0_HUMAN" 3 1349.7555 1.3 31073 15574 2 1349.755216 675.885 40S ribosomal protein S20 OS=Homo sapiens OX=9606 GN=RPS20 PE=1 SV=1 5.32 2839.1 - 2.11E+06 - - - -0.186 - 2.522 0.485 - 687.2 1 2 0 -0.0003 12 0 0 0 9.20E+08 7.07E+08 - - - 5.0571 0.9999 221125_WJC_METTL3_EV_vs_WT_F03.15575.15575.2 0.00333 22-Dec R.FLESLPEEEQQR[166.11].V "sp|P17480|UBF1_HUMAN,tr|E9PKP7|E9PKP7_HUMAN" 2 1513.7288 1.51 31074 15575 2 1513.728453 757.8717 Nucleolar transcription factor 1 OS=Homo sapiens OX=9606 GN=UBTF PE=1 SV=1 4.09 2839.2 - 1.82E+06 - - - -0.2345 - 2.407 0.468 - 381.5 1 2 0 -0.0004 12 0 0 0 5.84E+07 3.87E+07 - - - 4.8087 0.9996 221125_WJC_METTL3_EV_vs_WT_F03.15576.15576.2 0.000261 16-Sep R.QQLEALLNK[136.11].T "sp|Q9BRA0|LSMD1_HUMAN,tr|I3L4V0|I3L4V0_HUMAN,tr|I3L3Z2|I3L3Z2_HUMAN" 3 1063.6117 1.31 31075 15576 2 1063.611398 532.8131 "N-alpha-acetyltransferase 38, NatC auxiliary subunit OS=Homo sapiens OX=9606 GN=NAA38 PE=1 SV=1" 6 2839.3 - 1.58E+06 - - - -0.2924 - 1.848 0.342 - 267.3 1 2 0 -0.0003 9 0 0 0 3.74E+07 2.86E+07 - - - 3.3435 1 221125_WJC_METTL3_EV_vs_WT_F03.15578.15578.3 2.15E-06 14/44 K.APGFAHLAGLDK.M "sp|O75306|NDUS2_HUMAN,tr|A0A7I2V4X8|A0A7I2V4X8_HUMAN,tr|A0A7I2V4G5|A0A7I2V4G5_HUMAN,tr|A0A7I2YQG7|A0A7I2YQG7_HUMAN,tr|A0A7I2V596|A0A7I2V596_HUMAN,tr|A0A7I2YQD8|A0A7I2YQD8_HUMAN" 6 1195.635 0.14 31077 15578 3 1195.633463 399.5523 "NADH dehydrogenase [ubiquinone] iron-sulfur protein 2, mitochondrial OS=Homo sapiens OX=9606 GN=NDUFS2 PE=1 SV=2" 6.79 2839.4 - 1.36E+06 - - - -1.2495 - 2.925 0.502 - 202.3 1 2 0 -0.0015 12 0 0 0 3.71E+07 2.63E+08 - - - 7.1114 0.9885 221125_WJC_METTL3_EV_vs_WT_F03.15579.15579.3 0.136 Sep-40 R.LLASTLVHSVK.K "sp|Q9NYF8|BCLF1_HUMAN,tr|E9PKI6|E9PKI6_HUMAN,tr|A0A1W2PQ43|A0A1W2PQ43_HUMAN,tr|E9PK91|E9PK91_HUMAN,tr|E9PJA7|E9PJA7_HUMAN,tr|E9PK09|E9PK09_HUMAN,tr|E9PQN2|E9PQN2_HUMAN" 7 1166.7023 1.79 31078 15579 3 1166.699335 389.908 Bcl-2-associated transcription factor 1 OS=Homo sapiens OX=9606 GN=BCLAF1 PE=1 SV=2 8.76 2839.6 - 893267 - - - -2.5491 - 1.386 0.269 - 42.5 2 2 0 -0.003 11 0 0 0 2.44E+06 1.37E+06 - - - 2.3262 0.9985 221125_WJC_METTL3_EV_vs_WT_F03.15583.15583.2 0.00138 14/22 K.EGAAVIDVGINR.V "sp|P13995|MTDC_HUMAN,tr|A0A7I2V482|A0A7I2V482_HUMAN,tr|A0A7I2V2U6|A0A7I2V2U6_HUMAN,tr|A0A7I2YQD4|A0A7I2YQD4_HUMAN,tr|B9A062|B9A062_HUMAN" 5 1212.6463 1.48 31080 15583 2 1212.648995 607.3304 "Bifunctional methylenetetrahydrofolate dehydrogenase\cyclohydrolase, mitochondrial OS=Homo sapiens OX=9606 GN=MTHFD2 PE=1 SV=2" 4.37 2840.1 - 1.13E+07 - - - 2.2636 - 2.515 0.201 - 379.9 1 2 0 0.0027 12 0 0 0 1.53E+08 1.04E+08 - - - 2.9514 0.9991 221125_WJC_METTL3_EV_vs_WT_F03.15584.15584.2 0.000314 18-Oct K.LDVTSVEDYK.A "sp|P48643|TCPE_HUMAN,tr|E9PCA1|E9PCA1_HUMAN,tr|B7ZAR1|B7ZAR1_HUMAN,tr|E7ENZ3|E7ENZ3_HUMAN" 4 1167.5659 0.66 31081 15584 2 1167.561704 584.7902 T-complex protein 1 subunit epsilon OS=Homo sapiens OX=9606 GN=CCT5 PE=1 SV=1 4.03 2840.1 - 1.16E+07 - - - -3.6229 - 2.373 0.447 - 385.6 1 2 0 -0.0042 10 0 0 0 5.07E+08 7.71E+08 - - - 4.7533 0.9997 221125_WJC_METTL3_EV_vs_WT_F03.15585.15585.2 0.0731 22-Dec K.ASGPPVSELITK.A "sp|P10412|H14_HUMAN,sp|P16403|H12_HUMAN,sp|P16402|H13_HUMAN" 3 1197.6605 0.72 31082 15585 2 1197.660871 599.8375 Histone H1.4 OS=Homo sapiens OX=9606 GN=H1-4 PE=1 SV=2 6.05 2840.2 - 7.50E+06 - - - 0.3064 - 2.256 0.343 - 445.1 1 2 0 0.0004 12 0 0 0 7.40E+08 1.03E+09 - - - 3.715 0.9988 221125_WJC_METTL3_EV_vs_WT_F03.15586.15586.3 0.0182 Oct-32 K.LVK[136.11]EEVFWR[166.11].N sp|Q96A49|SYAP1_HUMAN 1 1222.6829 1.2 31083 15586 3 1222.68075 408.5682 Synapse-associated protein 1 OS=Homo sapiens OX=9606 GN=SYAP1 PE=1 SV=1 6.14 2840.2 - 5.12E+06 - - - -1.7699 - 2.241 0.334 - 181.5 1 2 1 -0.0022 9 0 0 0 1.09E+09 9.10E+08 - - - 4.6951 0.9954 221125_WJC_METTL3_EV_vs_WT_F03.15587.15587.3 0.00643 Nov-32 K.LVKEEVFWR.N sp|Q96A49|SYAP1_HUMAN 1 1204.6604 1.2 31084 15587 3 1204.656314 402.5608 Synapse-associated protein 1 OS=Homo sapiens OX=9606 GN=SYAP1 PE=1 SV=1 6.14 2840.3 - 4.35E+06 - - - -3.4284 - 2.202 0.329 - 177.8 1 2 1 -0.0041 9 0 0 0 1.09E+09 9.08E+08 - - - 4.5859 0.9997 221125_WJC_METTL3_EV_vs_WT_F03.15588.15588.2 0.000169 22-Dec R.LIDLHSPSEIVK[136.11].Q "sp|P60866|RS20_HUMAN,tr|A0A7P0S5H5|A0A7P0S5H5_HUMAN,tr|G3XAN0|G3XAN0_HUMAN" 3 1357.7697 1.3 31085 15588 2 1357.768007 679.8921 40S ribosomal protein S20 OS=Homo sapiens OX=9606 GN=RPS20 PE=1 SV=1 5.32 2840.3 - 2.73E+06 - - - -1.2226 - 2.386 0.374 - 526.2 1 2 0 -0.0017 12 0 0 0 9.20E+08 7.07E+08 - - - 4.091 0.9986 221125_WJC_METTL3_EV_vs_WT_F03.15589.15589.2 0.0241 16-Aug R.QQLEALLNK.T "sp|Q9BRA0|LSMD1_HUMAN,tr|I3L4V0|I3L4V0_HUMAN,tr|I3L3Z2|I3L3Z2_HUMAN" 3 1055.5975 1.31 31086 15589 2 1055.596017 528.806 "N-alpha-acetyltransferase 38, NatC auxiliary subunit OS=Homo sapiens OX=9606 GN=NAA38 PE=1 SV=1" 6 2840.4 - 2.55E+06 - - - -1.4134 - 1.705 0.25 - 195.7 1 2 0 -0.0015 9 0 0 0 3.74E+07 2.86E+07 - - - 2.4307 0.9899 221125_WJC_METTL3_EV_vs_WT_F03.15591.15591.2 0.000747 13/18 L.DLHSPSEIVK.Q "sp|P60866|RS20_HUMAN,tr|A0A7P0S5H5|A0A7P0S5H5_HUMAN,tr|G3XAN0|G3XAN0_HUMAN" 3 1123.5873 1.2 31088 15591 2 1123.585583 562.8009 40S ribosomal protein S20 OS=Homo sapiens OX=9606 GN=RPS20 PE=1 SV=1 5.32 2840.6 - 860932 - - - -1.5629 - 2.469 0.482 - 468.9 1 1 0 -0.0018 10 0 0 0 2.14E+08 1.79E+08 - - - 5.1233 0.9938 221125_WJC_METTL3_EV_vs_WT_F03.15597.15597.2 0.000197 14/20 L.IDLHSPSEIVK[136.11].Q "sp|P60866|RS20_HUMAN,tr|A0A7P0S5H5|A0A7P0S5H5_HUMAN,tr|G3XAN0|G3XAN0_HUMAN" 3 1244.6856 1.33 31092 15597 2 1244.685342 623.3501 40S ribosomal protein S20 OS=Homo sapiens OX=9606 GN=RPS20 PE=1 SV=1 5.32 2841.3 - 1.32E+06 - - - -0.2097 - 2.699 0.462 - 648.2 1 1 0 -0.0003 11 0 0 0 2.69E+08 2.01E+08 - - - 5.1392 0.9991 221125_WJC_METTL3_EV_vs_WT_F03.15600.15600.2 0.000109 13/24 R.LWEAVSGAQPVGR[166.11].E "sp|Q9UL40|ZN346_HUMAN,tr|B7Z6B6|B7Z6B6_HUMAN,tr|B7Z4N4|B7Z4N4_HUMAN,tr|D6RJ07|D6RJ07_HUMAN,tr|B7Z4J8|B7Z4J8_HUMAN,tr|B7Z6Q2|B7Z6Q2_HUMAN" 6 1378.7233 1.86 31095 15600 2 1378.728312 690.3689 Zinc finger protein 346 OS=Homo sapiens OX=9606 GN=ZNF346 PE=1 SV=1 6 2841.6 - 1.14E+06 - - - 3.6577 - 2.688 0.449 - 723.3 1 2 0 0.005 13 0 0 0 3.71E+07 1.99E+07 - - - 4.8935 0.9951 221125_WJC_METTL3_EV_vs_WT_F03.15602.15602.2 2.51E-08 14/24 N.LINYQDDAELATR.A "sp|P35222|CTNB1_HUMAN,sp|P14923|PLAK_HUMAN,tr|C9JKY1|C9JKY1_HUMAN,tr|A0A2R8Y5C3|A0A2R8Y5C3_HUMAN,tr|C9JK18|C9JK18_HUMAN,tr|A0A2R8YCH5|A0A2R8YCH5_HUMAN,tr|A0A2R8Y543|A0A2R8Y543_HUMAN,tr|A0A2R8Y750|A0A2R8Y750_HUMAN,tr|B4DGU4|B4DGU4_HUMAN,tr|C9JTX4|C9JTX4_HUMAN,tr|A0A2R8Y5A3|A0A2R8Y5A3_HUMAN,tr|A0A2R8Y804|A0A2R8Y804_HUMAN,tr|C9J826|C9J826_HUMAN,tr|A0A2R8Y5Z1|A0A2R8Y5Z1_HUMAN,tr|A0A2R8Y7Z0|A0A2R8Y7Z0_HUMAN" 15 1520.7471 999 31097 15602 2 1520.746913 761.3808 Catenin beta-1 OS=Homo sapiens OX=9606 GN=CTNNB1 PE=1 SV=1 4.03 2841.9 - 705692 - - - -0.1144 - 2.785 0.547 - 756.7 1 1 0 -0.0002 13 0 0 0 1.02E+07 0.00E+00 - - - 5.7098 0.985 221125_WJC_METTL3_EV_vs_WT_F03.15607.15607.2 0.000359 16/20 L.IDLHSPSEIVK.Q "sp|P60866|RS20_HUMAN,tr|A0A7P0S5H5|A0A7P0S5H5_HUMAN,tr|G3XAN0|G3XAN0_HUMAN" 3 1236.6714 1.33 31100 15607 2 1236.669288 619.343 40S ribosomal protein S20 OS=Homo sapiens OX=9606 GN=RPS20 PE=1 SV=1 5.32 2842.5 - 1.29E+06 - - - -1.7102 - 2.821 0.369 - 843.7 1 1 0 -0.0021 11 0 0 0 2.69E+08 2.01E+08 - - - 4.5713 0.9994 221125_WJC_METTL3_EV_vs_WT_F03.15610.15610.2 0.0135 18-Sep R.VTGGIFSVTK.G sp|Q8WUH6|TM263_HUMAN 1 1007.5651 0.57 31103 15610 2 1007.564467 504.7898 Transmembrane protein 263 OS=Homo sapiens OX=9606 GN=TMEM263 PE=1 SV=1 8.72 2842.8 - 1.07E+06 - - - -0.6749 - 1.67 0.336 - 185.6 1 2 0 -0.0007 10 0 0 0 2.23E+07 3.94E+07 - - - 2.9539 0.9999 221125_WJC_METTL3_EV_vs_WT_F03.15612.15612.3 0.000342 15/36 R.RVLDELTLAR.A "sp|Q04695|K1C17_HUMAN,sp|P02533|K1C14_HUMAN,sp|P08727|K1C19_HUMAN,sp|P08779|K1C16_HUMAN,sp|P19012|K1C15_HUMAN,tr|C9JM50|C9JM50_HUMAN,tr|C9JTG5|C9JTG5_HUMAN,tr|F5GWP8|F5GWP8_HUMAN,tr|K7EMS3|K7EMS3_HUMAN,tr|A8MT21|A8MT21_HUMAN" 10 1184.6877 57.3 31105 15612 3 1184.686621 395.9032 "Keratin, type I cytoskeletal 17 OS=Homo sapiens OX=9606 GN=KRT17 PE=1 SV=2" 6.07 2843.1 - 775228 - - - -0.9285 - 2.387 0.391 - 352.8 1 2 0 -0.0011 10 0 0 0 2.63E+08 4.59E+06 - - - 5.4398 0.9825 221125_WJC_METTL3_EV_vs_WT_F03.15614.15614.2 0.0201 18-Oct F.YYEILNSPDR[166.11].A "sp|P62258|1433E_HUMAN,tr|K7EM20|K7EM20_HUMAN" 2 1278.612 2.52 31107 15614 2 1278.610347 640.3133 14-3-3 protein epsilon OS=Homo sapiens OX=9606 GN=YWHAE PE=1 SV=1 4.37 2843.3 - 653481 - - - -1.2826 - 2.012 0.404 - 329.2 1 1 0 -0.0016 10 0 0 0 2.87E+07 1.14E+07 - - - 3.9759 0.9996 221125_WJC_METTL3_EV_vs_WT_F03.15617.15617.2 0.00108 14-Aug R.TDWDAGFK[136.11].E "sp|P52298|NCBP2_HUMAN,tr|C9JQX9|C9JQX9_HUMAN,tr|B3KSB0|B3KSB0_HUMAN" 3 946.4276 1.35 31108 15617 2 946.425708 474.2211 Nuclear cap-binding protein subunit 2 OS=Homo sapiens OX=9606 GN=NCBP2 PE=1 SV=1 4.21 2843.7 - 3.71E+06 - - - -1.9959 - 1.973 0.436 - 346.6 1 2 0 -0.0019 8 0 0 0 5.84E+07 4.34E+07 - - - 4.3102 0.9998 221125_WJC_METTL3_EV_vs_WT_F03.15618.15618.2 0.000199 14/24 R.LWEAVSGAQPVGR.E "sp|Q9UL40|ZN346_HUMAN,tr|B7Z6B6|B7Z6B6_HUMAN,tr|B7Z4N4|B7Z4N4_HUMAN,tr|D6RJ07|D6RJ07_HUMAN,tr|B7Z4J8|B7Z4J8_HUMAN,tr|B7Z6Q2|B7Z6Q2_HUMAN" 6 1368.715 1.83 31109 15618 2 1368.712739 685.3648 Zinc finger protein 346 OS=Homo sapiens OX=9606 GN=ZNF346 PE=1 SV=1 6 2843.8 - 1.57E+06 - - - -1.6512 - 2.742 0.4 - 840.6 1 2 0 -0.0023 13 0 0 0 3.64E+07 1.99E+07 - - - 4.5835 0.9997 221125_WJC_METTL3_EV_vs_WT_F03.15620.15620.2 0.00193 13/18 R.RVLDELTLAR.A "sp|Q04695|K1C17_HUMAN,sp|P02533|K1C14_HUMAN,sp|P08727|K1C19_HUMAN,sp|P08779|K1C16_HUMAN,sp|P19012|K1C15_HUMAN,tr|C9JM50|C9JM50_HUMAN,tr|C9JTG5|C9JTG5_HUMAN,tr|F5GWP8|F5GWP8_HUMAN,tr|K7EMS3|K7EMS3_HUMAN,tr|A8MT21|A8MT21_HUMAN" 10 1184.6877 8.37 31111 15620 2 1184.685661 593.3511 "Keratin, type I cytoskeletal 17 OS=Homo sapiens OX=9606 GN=KRT17 PE=1 SV=2" 6.07 2843.9 - 2.94E+06 - - - -1.7389 - 2.195 0.408 - 301.7 1 2 0 -0.0021 10 0 0 0 3.92E+08 4.69E+07 - - - 4.2483 0.9978 221125_WJC_METTL3_EV_vs_WT_F03.15621.15621.2 0.168 18-Sep R.VTGGIFSVTK[136.11].G sp|Q8WUH6|TM263_HUMAN 1 1015.5793 0.9 31112 15621 2 1015.580689 508.7969 Transmembrane protein 263 OS=Homo sapiens OX=9606 GN=TMEM263 PE=1 SV=1 8.72 2844 - 1.66E+06 - - - 1.3214 - 1.869 0.175 - 158.8 1 2 0 0.0013 10 0 0 0 1.92E+07 2.12E+07 - - - 2.0788 0.8105 221125_WJC_METTL3_EV_vs_WT_F03.15622.15622.3 0.0955 Dec-40 K.EVLAGRPLFPH.V "sp|Q00839|HNRPU_HUMAN,tr|A0A1W2PQL0|A0A1W2PQL0_HUMAN,tr|A0A1W2PPL4|A0A1W2PPL4_HUMAN,tr|A0A1W2PQ74|A0A1W2PQ74_HUMAN,tr|Q5RI18|Q5RI18_HUMAN,tr|A0A1W2PP35|A0A1W2PP35_HUMAN,tr|A0A1W2PPS1|A0A1W2PPS1_HUMAN,tr|A0A1W2PRZ7|A0A1W2PRZ7_HUMAN,tr|A0A1W2PPH7|A0A1W2PPH7_HUMAN,tr|A0A1W2PP34|A0A1W2PP34_HUMAN,tr|A0A1X7SBS1|A0A1X7SBS1_HUMAN" 11 1234.6822 1.08 31113 15622 3 1234.679366 412.568 Heterogeneous nuclear ribonucleoprotein U OS=Homo sapiens OX=9606 GN=HNRNPU PE=1 SV=6 6.85 2844.1 - 1.55E+06 - - - -2.3293 - 2.003 0.253 - 145.8 1 1 0 -0.0029 11 0 0 0 1.50E+08 1.39E+08 - - - 3.3333 0.9746 221125_WJC_METTL3_EV_vs_WT_F03.15625.15625.2 0.0189 20-Dec R.PMIHELLTEGR[166.11].R "sp|Q14974|IMB1_HUMAN,tr|J3KTM9|J3KTM9_HUMAN" 2 1304.6786 1.39 31116 15625 2 1304.675831 653.3466 Importin subunit beta-1 OS=Homo sapiens OX=9606 GN=KPNB1 PE=1 SV=2 5.41 2844.4 - 1.08E+06 - - - -2.1431 - 2.267 0.401 - 578.5 1 1 0 -0.0028 11 0 0 0 2.48E+07 1.78E+07 - - - 4.216 1 221125_WJC_METTL3_EV_vs_WT_F03.15626.15626.3 0.000109 14/36 R.VVFVFGPDK[136.11]K[136.11].L sp|P30041|PRDX6_HUMAN 1 1150.6721 0.01 31117 15626 3 1150.670654 384.5647 Peroxiredoxin-6 OS=Homo sapiens OX=9606 GN=PRDX6 PE=1 SV=3 8.56 2844.5 - 1.05E+06 - - - -1.2836 - 2.185 0.482 - 213.5 1 2 0 -0.0015 10 0 0 0 1.55E+06 1.06E+08 - - - 6.1961 0.921 221125_WJC_METTL3_EV_vs_WT_F03.15627.15627.3 0.355 Nov-32 R.QLHLNQLIR[166.11].T "sp|P49736|MCM2_HUMAN,tr|H0Y8E6|H0Y8E6_HUMAN" 2 1143.6752 0.001 31118 15627 3 1143.673388 382.2323 DNA replication licensing factor MCM2 OS=Homo sapiens OX=9606 GN=MCM2 PE=1 SV=4 9.76 2844.7 - 710315 - - - -1.5809 - 1.814 0.038 - 151.9 1 2 0 -0.0018 9 0 0 0 0.00E+00 9.60E+06 - - - 0.758 0.9999 221125_WJC_METTL3_EV_vs_WT_F03.15629.15629.2 1.10E-09 28-Dec R.ASYVAPLTAQPATYR[166.11].A sp|Q96PK6|RBM14_HUMAN 1 1617.839 1.92 31119 15629 2 1617.836754 809.9268 RNA-binding protein 14 OS=Homo sapiens OX=9606 GN=RBM14 PE=1 SV=2 8.63 2844.9 - 1.78E+07 - - - -1.405 - 2.301 0.622 - 325.5 1 2 0 -0.0023 15 0 0 0 2.13E+09 1.11E+09 - - - 5.6832 0.9999 221125_WJC_METTL3_EV_vs_WT_F03.15632.15632.2 9.77E-05 20-Nov K.NGVYISEENFR[166.11].V "sp|P52732|KIF11_HUMAN,tr|A0A7I2YQY4|A0A7I2YQY4_HUMAN,tr|A0A7I2V3A9|A0A7I2V3A9_HUMAN,tr|A0A7I2V3V3|A0A7I2V3V3_HUMAN" 4 1336.6287 3.87 31121 15632 2 1336.629277 669.3216 Kinesin-like protein KIF11 OS=Homo sapiens OX=9606 GN=KIF11 PE=1 SV=2 4.53 2845.2 - 3.08E+06 - - - 0.4317 - 2.412 0.467 - 429.8 1 2 0 0.0006 11 0 0 0 6.11E+08 1.58E+08 - - - 4.8719 0.9041 221125_WJC_METTL3_EV_vs_WT_F03.15635.15635.2 0.229 12-Aug V.KEEVFWR.N sp|Q96A49|SYAP1_HUMAN 1 992.508 1.36 31124 15635 2 992.506521 497.2613 Synapse-associated protein 1 OS=Homo sapiens OX=9606 GN=SYAP1 PE=1 SV=1 6.14 2845.5 - 1.75E+06 - - - -1.4559 - 1.716 0.201 - 252.7 1 1 0 -0.0014 7 0 0 0 2.37E+07 1.74E+07 - - - 2.2361 0.9981 221125_WJC_METTL3_EV_vs_WT_F03.15636.15636.2 5.20E-06 20-Nov R.LDLAAYDQEGR.R sp|Q8TEM1|PO210_HUMAN 1 1249.5939 3.29 31125 15636 2 1249.588324 625.8042 Nuclear pore membrane glycoprotein 210 OS=Homo sapiens OX=9606 GN=NUP210 PE=1 SV=3 4.03 2845.6 - 857577 - - - -4.447 - 2.51 0.409 - 622.4 1 2 0 -0.0056 11 0 0 0 1.12E+07 3.40E+06 - - - 4.5497 0.997 221125_WJC_METTL3_EV_vs_WT_F03.15637.15637.3 0.0255 Oct-32 K.LVKEEVFWR[166.11].N sp|Q96A49|SYAP1_HUMAN 1 1214.6687 - 31126 15637 3 1214.669813 405.8968 Synapse-associated protein 1 OS=Homo sapiens OX=9606 GN=SYAP1 PE=1 SV=1 6.14 2845.7 - 729528 - - - 0.9048 - 2.093 0.259 - 110 1 2 1 0.0011 9 0 0 0 - - - - - 3.6533 0.9953 221125_WJC_METTL3_EV_vs_WT_F03.15638.15638.2 1.42E-05 22-Nov K.VGDHQFLLYSGR[166.11].S sp|Q8IYS2|K2013_HUMAN 1 1400.7076 0.001 31127 15638 2 1400.70099 701.3611 Uncharacterized protein KIAA2013 OS=Homo sapiens OX=9606 GN=KIAA2013 PE=1 SV=1 6.71 2845.9 - 467388 - - - -4.7326 - 1.862 0.394 - 257.4 1 2 0 -0.0066 12 0 0 0 0.00E+00 7.11E+06 - - - 3.5847 0.9998 221125_WJC_METTL3_EV_vs_WT_F03.15639.15639.2 2.27E-06 26-Sep R.VEVGLSSC[160.03]QGDYIR[166.11].V "sp|O60231|DHX16_HUMAN,tr|Q5SQH5|Q5SQH5_HUMAN,tr|A0A140T8Y5|A0A140T8Y5_HUMAN" 3 1591.754 1.23 31128 15639 2 1591.756665 796.8843 Pre-mRNA-splicing factor ATP-dependent RNA helicase DHX16 OS=Homo sapiens OX=9606 GN=DHX16 PE=1 SV=2 4.37 2846 - 377942 - - - 1.6887 - 2.202 0.545 - 209 1 2 0 0.0027 14 0 0 0 1.26E+07 1.02E+07 - - - 5.0464 0.9996 221125_WJC_METTL3_EV_vs_WT_F03.15643.15643.2 0.00016 20-Nov K.QQISLATQMVR[166.11].M "sp|P48643|TCPE_HUMAN,tr|E9PCA1|E9PCA1_HUMAN,tr|B7ZAR1|B7ZAR1_HUMAN,tr|E7ENZ3|E7ENZ3_HUMAN" 4 1283.6895 0.6 31130 15643 2 1283.691377 642.852 T-complex protein 1 subunit epsilon OS=Homo sapiens OX=9606 GN=CCT5 PE=1 SV=1 9.75 2846.4 - 2.93E+06 - - - 1.4419 - 2.275 0.331 - 532.3 1 2 0 0.0019 11 0 0 0 1.11E+09 1.84E+09 - - - 3.7088 0.9998 221125_WJC_METTL3_EV_vs_WT_F03.15646.15646.2 1.61E-05 18-Sep R.VNC[160.03]LAPGLIK.T "sp|P0CG22|DR4L1_HUMAN,sp|Q9BTZ2|DHRS4_HUMAN,tr|H0YNP7|H0YNP7_HUMAN" 3 1083.6111 1.55 31133 15646 2 1083.612636 542.8128 Putative dehydrogenase\reductase SDR family member 4-like 1 OS=Homo sapiens OX=9606 GN=DHRS4L1 PE=5 SV=1 8.19 2846.7 - 881112 - - - 1.4627 - 2.144 0.514 - 310.4 1 2 0 0.0016 10 0 0 0 1.52E+07 9.83E+06 - - - 4.9658 1 221125_WJC_METTL3_EV_vs_WT_F03.15647.15647.2 4.66E-09 14/26 R.VEVGLSSC[160.03]QGDYIR.V "sp|O60231|DHX16_HUMAN,tr|Q5SQH5|Q5SQH5_HUMAN,tr|A0A140T8Y5|A0A140T8Y5_HUMAN" 3 1581.7457 1.25 31134 15647 2 1581.742589 791.8801 Pre-mRNA-splicing factor ATP-dependent RNA helicase DHX16 OS=Homo sapiens OX=9606 GN=DHX16 PE=1 SV=2 4.37 2846.8 - 791106 - - - -1.9712 - 2.741 0.675 - 645 1 2 0 -0.0031 14 0 0 0 1.26E+07 1.00E+07 - - - 6.5559 0.9977 221125_WJC_METTL3_EV_vs_WT_F03.15649.15649.2 0.0647 18-Sep R.QVLLGDQIPK[136.11].F sp|P28072|PSB6_HUMAN 1 1117.6587 0.5 31136 15649 2 1117.660939 559.8366 Proteasome subunit beta type-6 OS=Homo sapiens OX=9606 GN=PSMB6 PE=1 SV=4 5.84 2847.1 - 722431 - - - 2.04 - 1.852 0.22 - 211.7 1 2 0 0.0023 10 0 0 0 6.21E+06 1.24E+07 - - - 2.3854 1 221125_WJC_METTL3_EV_vs_WT_F03.15651.15651.2 4.73E-11 16/28 K.TGPAPATAGFYEYGK[136.11].A sp|Q5T481|RBM20_HUMAN 1 1536.734 1.15 31138 15651 2 1536.733315 769.3743 RNA-binding protein 20 OS=Homo sapiens OX=9606 GN=RBM20 PE=1 SV=3 5.66 2847.4 - 628170 - - - -0.4516 - 2.886 0.688 - 734 1 2 0 -0.0007 15 0 0 0 2.44E+07 2.12E+07 - - - 6.7281 1 221125_WJC_METTL3_EV_vs_WT_F03.15652.15652.2 5.11E-12 15/28 K.MEDSVGC[160.03]LETAEEVK.R sp|P35579|MYH9_HUMAN 1 1695.7332 1.16 31139 15652 2 1695.730441 848.8739 Myosin-9 OS=Homo sapiens OX=9606 GN=MYH9 PE=1 SV=4 3.91 2847.5 - 440918 - - - -1.5993 - 3.107 0.619 - 573.4 1 2 0 -0.0027 15 0 0 0 8.85E+06 7.60E+06 - - - 6.3992 0.9995 221125_WJC_METTL3_EV_vs_WT_F03.15655.15655.3 1.08E-05 14/40 K.FAAQELIEVK[136.11]R[166.11].G "sp|Q86U44|MTA70_HUMAN,tr|F5H6D8|F5H6D8_HUMAN,tr|H0YFV6|H0YFV6_HUMAN,tr|B4DTN4|B4DTN4_HUMAN" 4 1320.7521 0 31140 15655 3 1320.751064 441.258 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 6.14 2847.9 - 8.08E+07 - - - -0.7511 - 2.416 0.253 - 187.1 1 2 0 -0.001 11 0 0 0 1.51E+08 3.90E+10 - - - 3.8664 0.9995 221125_WJC_METTL3_EV_vs_WT_F03.15656.15656.2 0.000282 18-Aug R.NIYLMDTSGK[136.11].V "sp|P27694|RFA1_HUMAN,tr|I3L4R8|I3L4R8_HUMAN" 2 1148.5627 1.26 31141 15656 2 1148.565178 575.2886 Replication protein A 70 kDa DNA-binding subunit OS=Homo sapiens OX=9606 GN=RPA1 PE=1 SV=2 5.83 2847.9 - 5.66E+06 - - - 2.1488 - 1.8 0.473 - 150.3 1 2 0 0.0025 10 0 0 0 1.74E+08 1.37E+08 - - - 4.1745 0.9997 221125_WJC_METTL3_EV_vs_WT_F03.15657.15657.2 0.0012 16-Oct K.SGVLDTLTK[136.11].V "sp|Q99417|MYCBP_HUMAN,tr|A0A0D9SEI7|A0A0D9SEI7_HUMAN,tr|A0A087WV05|A0A087WV05_HUMAN" 3 940.5321 1.9 31142 15657 2 940.530663 471.2733 c-Myc-binding protein OS=Homo sapiens OX=9606 GN=MYCBP PE=1 SV=3 5.55 2848 - 6.92E+06 - - - -1.4875 - 1.912 0.425 - 324.7 1 2 0 -0.0014 9 0 0 0 1.74E+08 9.19E+07 - - - 4.0547 0.9999 221125_WJC_METTL3_EV_vs_WT_F03.15658.15658.2 1.45E-08 14/20 K.FAAQELIEVK[136.11]R[166.11].G "sp|Q86U44|MTA70_HUMAN,tr|F5H6D8|F5H6D8_HUMAN,tr|H0YFV6|H0YFV6_HUMAN,tr|B4DTN4|B4DTN4_HUMAN" 4 1320.7521 0 31143 15658 2 1320.750696 661.3833 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 6.14 2848 - 6.16E+06 - - - -1.0297 - 2.906 0.48 - 994.1 1 2 0 -0.0014 11 0 0 0 2.86E+06 4.39E+09 - - - 5.4717 0.9998 221125_WJC_METTL3_EV_vs_WT_F03.15659.15659.3 0.0026 14/40 K.FAAQELIEVKR[166.11].G "sp|Q86U44|MTA70_HUMAN,tr|F5H6D8|F5H6D8_HUMAN,tr|H0YFV6|H0YFV6_HUMAN,tr|B4DTN4|B4DTN4_HUMAN" 4 1312.7379 - 31144 15659 3 1312.738231 438.5866 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 6.14 2848.1 - 1.56E+06 - - - 0.2857 - 2.202 0.343 - 122.3 2 2 0 0.0004 11 0 0 0 - - - - - 4.4671 0.9849 221125_WJC_METTL3_EV_vs_WT_F03.15660.15660.2 0.000276 16-Oct A.AQELIEVK[136.11]R[166.11].G "sp|Q86U44|MTA70_HUMAN,tr|F5H6D8|F5H6D8_HUMAN,tr|H0YFV6|H0YFV6_HUMAN,tr|B4DTN4|B4DTN4_HUMAN" 4 1102.6465 0.01 31145 15660 2 1102.644555 552.3305 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 6.19 2848.2 - 1.36E+06 - - - -1.7893 - 2.148 0.459 - 639.5 1 1 0 -0.002 9 0 0 0 1.14E+07 1.06E+09 - - - 4.6424 1 221125_WJC_METTL3_EV_vs_WT_F03.15663.15663.3 1.54E-11 19/52 K.LVR[166.11]PPVQVYGIEGR[166.11].Y "sp|P48047|ATPO_HUMAN,tr|H7C086|H7C086_HUMAN,tr|H7C0C1|H7C0C1_HUMAN,tr|A0A494C0K9|A0A494C0K9_HUMAN" 4 1601.9157 1.01 31146 15663 3 1601.913192 534.9792 "ATP synthase subunit O, mitochondrial OS=Homo sapiens OX=9606 GN=ATP5PO PE=1 SV=1" 8.75 2848.6 - 2.67E+06 - - - -1.535 - 3.455 0.508 - 640.2 1 2 0 -0.0025 14 0 0 0 4.80E+08 4.73E+08 - - - 7.4979 0.9986 221125_WJC_METTL3_EV_vs_WT_F03.15664.15664.2 0.000264 22-Oct K.FLIPNASQAESK[136.11].V "sp|P63104|1433Z_HUMAN,tr|E7EX29|E7EX29_HUMAN,tr|E7ESK7|E7ESK7_HUMAN,tr|B0AZS6|B0AZS6_HUMAN" 4 1311.6914 1.89 31147 15664 2 1311.685674 656.853 14-3-3 protein zeta\delta OS=Homo sapiens OX=9606 GN=YWHAZ PE=1 SV=1 6 2848.6 - 2.16E+06 - - - -4.3776 - 2.157 0.53 - 277.8 1 2 0 -0.0057 12 0 0 0 3.58E+08 1.90E+08 - - - 4.9764 0.9998 221125_WJC_METTL3_EV_vs_WT_F03.15665.15665.2 5.26E-05 16-Oct K.SGVLDTLTK.V "sp|Q99417|MYCBP_HUMAN,tr|A0A0D9SEI7|A0A0D9SEI7_HUMAN,tr|A0A087WV05|A0A087WV05_HUMAN" 3 932.5179 1.9 31148 15665 2 932.516259 467.2662 c-Myc-binding protein OS=Homo sapiens OX=9606 GN=MYCBP PE=1 SV=3 5.55 2848.7 - 1.07E+07 - - - -1.719 - 2.229 0.536 - 326 1 2 0 -0.0016 9 0 0 0 1.74E+08 9.19E+07 - - - 5.3183 0.9991 221125_WJC_METTL3_EV_vs_WT_F03.15667.15667.2 0.0054 20-Oct K.VAASVLNPYVK.R "sp|P48047|ATPO_HUMAN,tr|H7C0C1|H7C0C1_HUMAN,tr|A0A494C0K9|A0A494C0K9_HUMAN" 3 1159.6601 1.18 31150 15667 2 1159.658819 580.8373 "ATP synthase subunit O, mitochondrial OS=Homo sapiens OX=9606 GN=ATP5PO PE=1 SV=1" 8.56 2848.9 - 847176 - - - -1.1133 - 2.115 0.221 - 242.8 1 2 0 -0.0013 11 0 0 0 1.16E+07 9.83E+06 - - - 2.6993 0.9998 221125_WJC_METTL3_EV_vs_WT_F03.15669.15669.2 6.09E-08 15/28 K.TGPAPATAGFYEYGK.A sp|Q5T481|RBM20_HUMAN 1 1528.7198 1.15 31152 15669 2 1528.716587 765.3672 RNA-binding protein 20 OS=Homo sapiens OX=9606 GN=RBM20 PE=1 SV=3 5.66 2849.1 - 608074 - - - -2.1076 - 2.566 0.584 - 712.6 1 2 0 -0.0032 15 0 0 0 2.44E+07 2.12E+07 - - - 5.6702 1 221125_WJC_METTL3_EV_vs_WT_F03.15670.15670.2 5.38E-08 15/32 R.LGSSGLGSASSIQAAVR[166.11].Q "sp|Q7Z6Z7|HUWE1_HUMAN,tr|H0Y659|H0Y659_HUMAN" 2 1569.835 0.19 31153 15670 2 1569.832518 785.9248 E3 ubiquitin-protein ligase HUWE1 OS=Homo sapiens OX=9606 GN=HUWE1 PE=1 SV=3 9.75 2849.2 - 453604 - - - -1.5836 - 3.403 0.556 - 563.3 1 2 0 -0.0025 17 0 0 0 2.62E+06 1.37E+07 - - - 6.1577 0.9998 221125_WJC_METTL3_EV_vs_WT_F03.15672.15672.2 0.000407 14-Jul K.EC[160.03]ADLWPR.L "sp|P62829|RL23_HUMAN,tr|J3KTJ3|J3KTJ3_HUMAN" 2 1045.4651 1.01 31154 15672 2 1045.464569 523.7398 60S ribosomal protein L23 OS=Homo sapiens OX=9606 GN=RPL23 PE=1 SV=1 4.37 2849.5 - 1.87E+06 - - - -0.5223 - 1.658 0.454 - 221.5 1 2 0 -0.0005 8 0 0 0 1.47E+08 1.46E+08 - - - 3.919 0.9703 221125_WJC_METTL3_EV_vs_WT_F03.15676.15676.2 0.057 14-Sep A.QELIEVK[136.11]R[166.11].G "sp|Q86U44|MTA70_HUMAN,tr|F5H6D8|F5H6D8_HUMAN,tr|H0YFV6|H0YFV6_HUMAN,tr|B4DTN4|B4DTN4_HUMAN" 4 1031.6094 0 31158 15676 2 1031.608073 516.812 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 6.14 2849.8 - 1.38E+06 - - - -1.3009 - 1.889 0.323 - 390.8 1 1 0 -0.0013 8 0 0 0 7.42E+05 2.22E+08 - - - 3.3445 0.9997 221125_WJC_METTL3_EV_vs_WT_F03.15677.15677.3 0.00737 Nov-40 K.QQISLATQMVR[166.11].M "sp|P48643|TCPE_HUMAN,tr|E9PCA1|E9PCA1_HUMAN,tr|B7ZAR1|B7ZAR1_HUMAN,tr|E7ENZ3|E7ENZ3_HUMAN" 4 1283.6895 0.75 31159 15677 3 1283.690571 428.9038 T-complex protein 1 subunit epsilon OS=Homo sapiens OX=9606 GN=CCT5 PE=1 SV=1 9.75 2849.9 - 988839 - - - 0.8141 - 1.932 0.345 - 275.6 1 2 0 0.001 11 0 0 0 3.38E+07 4.53E+07 - - - 4.257 0.9915 221125_WJC_METTL3_EV_vs_WT_F03.15678.15678.2 3.34E-06 22-Nov N.FESDEVELSYAK.N "sp|Q00839|HNRPU_HUMAN,tr|A0A1W2PQL0|A0A1W2PQL0_HUMAN,tr|A0A1W2PPL4|A0A1W2PPL4_HUMAN,tr|A0A1W2PQ74|A0A1W2PQ74_HUMAN,tr|Q5RI18|Q5RI18_HUMAN,tr|A0A1W2PP35|A0A1W2PP35_HUMAN,tr|A0A1W2PPS1|A0A1W2PPS1_HUMAN,tr|A0A1W2PRZ7|A0A1W2PRZ7_HUMAN,tr|A0A1W2PPH7|A0A1W2PPH7_HUMAN,tr|A0A1W2PP34|A0A1W2PP34_HUMAN,tr|A0A1X7SBS1|A0A1X7SBS1_HUMAN" 11 1415.6456 1.04 31160 15678 2 1415.643498 708.8301 Heterogeneous nuclear ribonucleoprotein U OS=Homo sapiens OX=9606 GN=HNRNPU PE=1 SV=6 4 2850 - 973111 - - - -1.5138 - 2.358 0.559 - 260.7 1 1 0 -0.0021 12 0 0 0 3.92E+07 3.78E+07 - - - 5.4262 0.9998 221125_WJC_METTL3_EV_vs_WT_F03.15681.15681.2 0.000858 18-Sep R.NIYLMDTSGK.V "sp|P27694|RFA1_HUMAN,tr|I3L4R8|I3L4R8_HUMAN" 2 1140.5485 1.27 31161 15681 2 1140.547863 571.2815 Replication protein A 70 kDa DNA-binding subunit OS=Homo sapiens OX=9606 GN=RPA1 PE=1 SV=2 5.83 2850.4 - 8.49E+06 - - - -0.5673 - 1.736 0.479 - 213.9 1 2 0 -0.0006 10 0 0 0 1.74E+08 1.37E+08 - - - 4.1183 0.9927 221125_WJC_METTL3_EV_vs_WT_F03.15682.15682.2 1.47E-05 18-Oct F.AAQELIEVK[136.11]R[166.11].G "sp|Q86U44|MTA70_HUMAN,tr|F5H6D8|F5H6D8_HUMAN,tr|H0YFV6|H0YFV6_HUMAN,tr|B4DTN4|B4DTN4_HUMAN" 4 1173.6836 0.01 31162 15682 2 1173.682279 587.8491 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 6.19 2850.4 - 9.40E+06 - - - -1.1613 - 2.507 0.507 - 562.8 1 1 0 -0.0014 10 0 0 0 5.94E+06 9.82E+08 - - - 5.3507 1 221125_WJC_METTL3_EV_vs_WT_F03.15683.15683.3 1.58E-08 23/52 K.LVRPPVQVYGIEGR.Y "sp|P48047|ATPO_HUMAN,tr|H7C086|H7C086_HUMAN,tr|H7C0C1|H7C0C1_HUMAN,tr|A0A494C0K9|A0A494C0K9_HUMAN" 4 1581.8991 0.98 31163 15683 3 1581.897872 528.307 "ATP synthase subunit O, mitochondrial OS=Homo sapiens OX=9606 GN=ATP5PO PE=1 SV=1" 8.75 2850.5 - 3.61E+06 - - - -0.7832 - 3.616 0.632 - 1065.1 1 2 0 -0.0012 14 0 0 0 4.42E+08 4.51E+08 - - - 9.0017 0.9993 221125_WJC_METTL3_EV_vs_WT_F03.15686.15686.2 2.80E-05 18-Oct R.VWVSENFQER.H "sp|Q9Y4A5|TRRAP_HUMAN,tr|H0Y4W2|H0Y4W2_HUMAN,tr|F2Z2U4|F2Z2U4_HUMAN" 3 1292.6149 2.31 31166 15686 2 1292.611152 647.3148 Transformation\transcription domain-associated protein OS=Homo sapiens OX=9606 GN=TRRAP PE=1 SV=3 4.53 2850.9 - 755145 - - - -2.9382 - 1.913 0.465 - 437.9 1 2 0 -0.0038 10 0 0 0 1.51E+07 6.54E+06 - - - 4.2849 0.9983 221125_WJC_METTL3_EV_vs_WT_F03.15687.15687.2 0.0116 28-Aug K.AVTEGAQAVEEPSIC[160.03].- "sp|P28331|NDUS1_HUMAN,tr|B4DJ81|B4DJ81_HUMAN" 2 1559.7137 - 31167 15687 2 1559.715242 780.8641 "NADH-ubiquinone oxidoreductase 75 kDa subunit, mitochondrial OS=Homo sapiens OX=9606 GN=NDUFS1 PE=1 SV=3" 3.67 2851 - 704815 - - - 0.9643 - 1.256 0.346 - 65.7 1 2 0 0.0015 15 0 0 0 - - - - - 2.1565 0.9876 221125_WJC_METTL3_EV_vs_WT_F03.15688.15688.2 2.4 16-Jul R.VQQIQLLGR[166.11].D "sp|Q9HD26|GOPC_HUMAN,tr|F5H1Y4|F5H1Y4_HUMAN" 2 1063.6377 1.15 31168 15688 2 1063.636408 532.8262 Golgi-associated PDZ and coiled-coil motif-containing protein OS=Homo sapiens OX=9606 GN=GOPC PE=1 SV=1 9.72 2851.1 - 568323 - - - -1.2598 - 1.691 0.034 - 159.5 2 2 0 -0.0013 9 0 0 0 1.15E+07 9.94E+06 - - - 0.677 0.9999 221125_WJC_METTL3_EV_vs_WT_F03.15693.15693.3 2.29E-05 13/40 R.MFADYLAHESR.R "sp|O14579|COPE_HUMAN,tr|M0QXB4|M0QXB4_HUMAN,tr|M0R061|M0R061_HUMAN" 3 1338.6027 1.36 31171 15693 3 1338.598011 447.2082 Coatomer subunit epsilon OS=Homo sapiens OX=9606 GN=COPE PE=1 SV=3 5.3 2851.7 - 3.07E+06 - - - -3.4812 - 2.601 0.552 - 304.7 1 2 0 -0.0047 11 0 0 0 7.46E+07 5.48E+07 - - - 7.4085 0.9799 221125_WJC_METTL3_EV_vs_WT_F03.15701.15701.2 0.000126 13/22 N.FESDEVELSYAK[136.11].N "sp|Q00839|HNRPU_HUMAN,tr|A0A1W2PQL0|A0A1W2PQL0_HUMAN,tr|A0A1W2PPL4|A0A1W2PPL4_HUMAN,tr|A0A1W2PQ74|A0A1W2PQ74_HUMAN,tr|Q5RI18|Q5RI18_HUMAN,tr|A0A1W2PP35|A0A1W2PP35_HUMAN,tr|A0A1W2PPS1|A0A1W2PPS1_HUMAN,tr|A0A1W2PRZ7|A0A1W2PRZ7_HUMAN,tr|A0A1W2PPH7|A0A1W2PPH7_HUMAN,tr|A0A1W2PP34|A0A1W2PP34_HUMAN,tr|A0A1X7SBS1|A0A1X7SBS1_HUMAN" 11 1423.6598 1.01 31177 15701 2 1423.656098 712.8372 Heterogeneous nuclear ribonucleoprotein U OS=Homo sapiens OX=9606 GN=HNRNPU PE=1 SV=6 4 2852.5 - 2.81E+06 - - - -2.6291 - 2.429 0.521 - 390.1 1 1 0 -0.0037 12 0 0 0 3.79E+07 3.76E+07 - - - 5.223 0.9989 221125_WJC_METTL3_EV_vs_WT_F03.15703.15703.2 3.37E-05 18-Dec K.SC[160.03]AEWVSLSK.A sp|O75947|ATP5H_HUMAN 1 1165.5438 1.49 31179 15703 2 1165.547221 583.7792 "ATP synthase subunit d, mitochondrial OS=Homo sapiens OX=9606 GN=ATP5PD PE=1 SV=3" 5.72 2852.8 - 1.16E+06 - - - 2.9703 - 1.992 0.39 - 547.5 1 2 0 0.0035 10 0 0 0 5.89E+07 3.95E+07 - - - 3.844 0.8615 221125_WJC_METTL3_EV_vs_WT_F03.15707.15707.2 0.183 26-Sep R.FNPDGEEEDVTVQE.- "sp|Q5SW79|CE170_HUMAN,tr|H0Y2V6|H0Y2V6_HUMAN,tr|E7EMW0|E7EMW0_HUMAN,tr|E7EWM2|E7EWM2_HUMAN" 4 1606.6635 - 31181 15707 2 1606.65526 804.339 Centrosomal protein of 170 kDa OS=Homo sapiens OX=9606 GN=CEP170 PE=1 SV=1 3.56 2853.3 - 1.36E+06 - - - -5.1137 - 1.112 0.203 - 135 1 2 0 -0.0082 14 0 0 0 - - - - - 0.8042 1 221125_WJC_METTL3_EV_vs_WT_F03.15709.15709.2 2.24E-07 14/20 K.C[160.03]C[160.03]SGAIIVLTK.S "sp|P14618|KPYM_HUMAN,tr|B4DNK4|B4DNK4_HUMAN" 2 1220.6257 0.75 31183 15709 2 1220.621467 611.3201 Pyruvate kinase PKM OS=Homo sapiens OX=9606 GN=PKM PE=1 SV=4 8.06 2853.5 - 2.00E+06 - - - -3.4802 - 2.94 0.598 - 689.6 1 2 0 -0.0042 11 0 0 0 7.07E+07 9.47E+07 - - - 6.3738 0.9998 221125_WJC_METTL3_EV_vs_WT_F03.15713.15713.3 1.21E-06 17/48 K.ELVEFAQDDDRLR.E sp|Q14677|EPN4_HUMAN 1 1604.7794 1.71 31184 15713 3 1604.775596 535.9338 Clathrin interactor 1 OS=Homo sapiens OX=9606 GN=CLINT1 PE=1 SV=1 4.11 2854.1 - 1.28E+07 - - - -2.4016 - 2.645 0.538 - 628.8 1 2 1 -0.0039 13 0 0 0 4.65E+08 2.72E+08 - - - 7.1743 0.998 221125_WJC_METTL3_EV_vs_WT_F03.15719.15719.2 2.13E-05 16/24 K.ELVEFAQDDDRLR.E sp|Q14677|EPN4_HUMAN 1 1604.7794 2.08 31188 15719 2 1604.776459 803.397 Clathrin interactor 1 OS=Homo sapiens OX=9606 GN=CLINT1 PE=1 SV=1 4.11 2854.7 - 1.41E+06 - - - -1.8638 - 2.831 0.502 - 437 1 2 1 -0.003 13 0 0 0 4.18E+07 2.01E+07 - - - 5.4186 0.9998 221125_WJC_METTL3_EV_vs_WT_F03.15726.15726.2 9.45E-08 14/26 K.LVEQLDIEETEQSK[136.11].L "sp|Q92552|RT27_HUMAN,tr|G5EA06|G5EA06_HUMAN,tr|D6RH20|D6RH20_HUMAN" 3 1667.8345 1.73 31193 15726 2 1667.8307 834.9245 "28S ribosomal protein S27, mitochondrial OS=Homo sapiens OX=9606 GN=MRPS27 PE=1 SV=3" 3.91 2855.7 - 1.34E+06 - - - -2.285 - 2.895 0.515 - 562.3 1 2 0 -0.0038 14 0 0 0 2.83E+07 1.64E+07 - - - 5.5111 0.9979 221125_WJC_METTL3_EV_vs_WT_F03.15729.15729.2 4.73E-06 18-Nov K.NGTTYEGIFK.T "sp|Q8WWM7|ATX2L_HUMAN,tr|H3BSQ5|H3BSQ5_HUMAN,tr|H3BSK9|H3BSK9_HUMAN,tr|H3BUE3|H3BUE3_HUMAN,tr|H3BUF6|H3BUF6_HUMAN" 5 1128.5451 1.24 31194 15729 2 1128.539567 565.2798 Ataxin-2-like protein OS=Homo sapiens OX=9606 GN=ATXN2L PE=1 SV=2 6 2856 - 2.84E+06 - - - -4.9373 - 2.201 0.499 - 439.9 1 2 0 -0.0056 10 0 0 0 1.02E+08 8.21E+07 - - - 4.927 0.9485 221125_WJC_METTL3_EV_vs_WT_F03.15730.15730.3 0.322 Sep-36 K.LKEELIDAIR.Q "sp|Q8N8S7|ENAH_HUMAN,tr|A0A0U1RRM6|A0A0U1RRM6_HUMAN" 2 1198.6921 1.1 31195 15730 3 1198.690553 400.5713 Protein enabled homolog OS=Homo sapiens OX=9606 GN=ENAH PE=1 SV=2 4.68 2856.1 - 2.06E+06 - - - -1.3223 - 1.546 0.179 - 84.7 1 2 1 -0.0016 10 0 0 0 8.22E+07 7.45E+07 - - - 1.8076 0.9995 221125_WJC_METTL3_EV_vs_WT_F03.15735.15735.2 0.000453 22-Oct R.ADGYEPPVQESV.- "sp|P61247|RS3A_HUMAN,tr|D6R9B6|D6R9B6_HUMAN,tr|H0Y9Y4|H0Y9Y4_HUMAN,tr|D6RAT0|D6RAT0_HUMAN" 4 1289.5776 - 31198 15735 2 1289.575824 645.7961 40S ribosomal protein S3a OS=Homo sapiens OX=9606 GN=RPS3A PE=1 SV=2 3.57 2856.8 - 1.59E+06 - - - -1.3477 - 1.782 0.398 - 314.1 1 2 0 -0.0017 12 0 0 0 - - - - - 3.5002 0.9997 221125_WJC_METTL3_EV_vs_WT_F03.15744.15744.2 0.00503 16-Sep R.MAFTC[160.03]SFC[160.03]K[136.11].F "sp|Q5BKZ1|ZN326_HUMAN,tr|A0A0A0MRN4|A0A0A0MRN4_HUMAN" 2 1158.4752 0.9 31205 15744 2 1158.474174 580.2449 DBIRD complex subunit ZNF326 OS=Homo sapiens OX=9606 GN=ZNF326 PE=1 SV=2 7.82 2857.9 - 1.52E+06 - - - -0.8494 - 1.596 0.452 - 293.4 1 2 0 -0.001 9 0 0 0 2.47E+07 2.75E+07 - - - 3.7317 0.9956 221125_WJC_METTL3_EV_vs_WT_F03.15746.15746.2 2.33E-07 24-Dec K.ELVEFAQDDDR[166.11]LR[166.11].E sp|Q14677|EPN4_HUMAN 1 1624.796 2.08 31207 15746 2 1624.791285 813.4053 Clathrin interactor 1 OS=Homo sapiens OX=9606 GN=CLINT1 PE=1 SV=1 4.11 2858.1 - 830471 - - - -2.8957 - 2.512 0.534 - 236.4 1 2 1 -0.0047 13 0 0 0 4.18E+07 2.01E+07 - - - 5.3476 1 221125_WJC_METTL3_EV_vs_WT_F03.15749.15749.2 3.16E-08 13/24 R.FSGSGSGTDFTLK.L "sp|A2NJV5|KV229_HUMAN,sp|A0A087WW87|KV240_HUMAN,sp|P06310|KV230_HUMAN,sp|A0A075B6S2|KVD29_HUMAN,sp|P01614|KVD40_HUMAN,sp|P01615|KVD28_HUMAN,sp|A0A075B6S6|KVD30_HUMAN,sp|A0A075B6P5|KV228_HUMAN,sp|A0A0A0MRZ7|KVD26_HUMAN" 9 1302.6092 226.52 31208 15749 2 1302.606689 652.3119 Immunoglobulin kappa variable 2-29 OS=Homo sapiens OX=9606 GN=IGKV2-29 PE=3 SV=2 5.84 2858.5 - 9.40E+06 - - - -1.9246 - 2.44 0.603 - 331.9 1 2 0 -0.0025 13 0 0 0 3.17E+08 1.40E+06 - - - 5.7833 0.9956 221125_WJC_METTL3_EV_vs_WT_F03.15750.15750.3 0.0103 Dec-40 K.FAAQELIEVKR.G "sp|Q86U44|MTA70_HUMAN,tr|F5H6D8|F5H6D8_HUMAN,tr|H0YFV6|H0YFV6_HUMAN,tr|B4DTN4|B4DTN4_HUMAN" 4 1302.7296 0 31209 15750 3 1302.730623 435.2505 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 6.14 2858.6 - 4.01E+06 - - - 0.796 - 2.097 0.15 - 136.9 1 2 0 0.001 11 0 0 0 1.51E+08 3.90E+10 - - - 2.3157 0.9998 221125_WJC_METTL3_EV_vs_WT_F03.15752.15752.2 3.51E-05 13/20 R.GVEIC[160.03]IATPGR.L "sp|Q92841|DDX17_HUMAN,sp|P17844|DDX5_HUMAN,tr|A0A7I2V5F5|A0A7I2V5F5_HUMAN,tr|J3KRZ1|J3KRZ1_HUMAN,tr|J3QSF1|J3QSF1_HUMAN,tr|A0A7I2V507|A0A7I2V507_HUMAN,tr|A0A5H1ZRQ2|A0A5H1ZRQ2_HUMAN,tr|J3KTA4|J3KTA4_HUMAN,tr|A0A0G2JLI4|A0A0G2JLI4_HUMAN,tr|A0A1X7SBZ2|A0A1X7SBZ2_HUMAN,tr|A0A7I2V2S0|A0A7I2V2S0_HUMAN" 11 1171.6019 1.25 31211 15752 2 1171.600285 586.8082 Probable ATP-dependent RNA helicase DDX17 OS=Homo sapiens OX=9606 GN=DDX17 PE=1 SV=2 5.99 2858.6 - 2.07E+07 - - - -1.4152 - 2.482 0.483 - 793.3 1 2 0 -0.0017 11 0 0 0 5.80E+08 4.65E+08 - - - 5.0672 0.9992 221125_WJC_METTL3_EV_vs_WT_F03.15753.15753.2 4.94E-05 18-Nov K.YQNYIMEGVK.A "sp|Q9Y508|RN114_HUMAN,tr|A0A096LP02|A0A096LP02_HUMAN,tr|A0A096LNV3|A0A096LNV3_HUMAN" 3 1243.5907 1.48 31212 15753 2 1243.586538 622.8026 E3 ubiquitin-protein ligase RNF114 OS=Homo sapiens OX=9606 GN=RNF114 PE=1 SV=1 6 2858.7 - 2.25E+06 - - - -3.354 - 1.981 0.496 - 304.7 1 2 0 -0.0042 10 0 0 0 3.27E+07 2.20E+07 - - - 4.6113 0.9999 221125_WJC_METTL3_EV_vs_WT_F03.15754.15754.2 9.19E-05 18-Dec R.LGDLYEEEMR[166.11].E "sp|P08670|VIME_HUMAN,tr|B0YJC4|B0YJC4_HUMAN" 2 1263.5681 2.35 31213 15754 2 1263.567749 632.7913 Vimentin OS=Homo sapiens OX=9606 GN=VIM PE=1 SV=4 4 2858.8 - 1.47E+06 - - - -0.2564 - 2.126 0.463 - 547.9 1 2 0 -0.0003 10 0 0 0 4.49E+07 1.91E+07 - - - 4.5659 1 221125_WJC_METTL3_EV_vs_WT_F03.15758.15758.2 0.000186 16/22 R.LNDSILQATEQR.R sp|P15924|DESP_HUMAN 1 1386.7103 30.58 31215 15758 2 1386.708874 694.3624 Desmoplakin OS=Homo sapiens OX=9606 GN=DSP PE=1 SV=3 4.37 2859.3 - 3.88E+06 - - - -1.0334 - 3.143 0.581 - 1131.7 1 2 0 -0.0014 12 0 0 0 1.01E+08 3.32E+06 - - - 6.345 0.999 221125_WJC_METTL3_EV_vs_WT_F03.15760.15760.3 9.34E-05 15/36 R.REPLSLINVR.K sp|Q96HS1|PGAM5_HUMAN 1 1195.7037 0.73 31217 15760 3 1195.702165 399.5752 "Serine\threonine-protein phosphatase PGAM5, mitochondrial OS=Homo sapiens OX=9606 GN=PGAM5 PE=1 SV=2" 9.6 2859.6 - 1.45E+06 - - - -1.2888 - 2.779 0.167 - 325.7 1 2 0 -0.0015 10 0 0 0 3.79E+07 5.15E+07 - - - 3.3864 0.9993 221125_WJC_METTL3_EV_vs_WT_F03.15764.15764.2 0.00758 16-Aug R.EQVNDLFSR[166.11].K "sp|P78347|GTF2I_HUMAN,sp|Q86UP8|GTD2A_HUMAN,sp|Q6EKJ0|GTD2B_HUMAN,tr|A0A494C1N8|A0A494C1N8_HUMAN,tr|A0A087WW90|A0A087WW90_HUMAN,tr|A0A0D9SF80|A0A0D9SF80_HUMAN,tr|A0A494C0I1|A0A494C0I1_HUMAN,tr|A0A494C1K3|A0A494C1K3_HUMAN" 8 1116.5439 1.46 31219 15764 2 1116.541181 559.2792 General transcription factor II-I OS=Homo sapiens OX=9606 GN=GTF2I PE=1 SV=2 4.37 2860 - 2.78E+06 - - - -2.4415 - 1.709 0.449 - 269.2 1 2 0 -0.0027 9 0 0 0 1.64E+09 1.13E+09 - - - 3.9069 0.9989 221125_WJC_METTL3_EV_vs_WT_F03.15765.15765.2 0.156 22-Oct R.ALESGDVNTVWK[136.11].Q "sp|P46940|IQGA1_HUMAN,tr|A0A0J9YXZ5|A0A0J9YXZ5_HUMAN" 2 1325.6707 1.19 31220 15765 2 1325.671002 663.8426 Ras GTPase-activating-like protein IQGAP1 OS=Homo sapiens OX=9606 GN=IQGAP1 PE=1 SV=1 4.37 2860 - 8.01E+06 - - - 0.2421 - 1.553 0.288 - 146.3 1 2 0 0.0003 12 0 0 0 5.23E+07 4.38E+07 - - - 2.3263 1 221125_WJC_METTL3_EV_vs_WT_F03.15766.15766.2 0.0024 17/28 K.VALVYGQMNEPPGAR.A "sp|P06576|ATPB_HUMAN,tr|F8W0P7|F8W0P7_HUMAN,tr|H0YH81|H0YH81_HUMAN" 3 1600.8032 1.92 31221 15766 2 1600.801239 801.4089 "ATP synthase subunit beta, mitochondrial OS=Homo sapiens OX=9606 GN=ATP5F1B PE=1 SV=3" 5.97 2860.2 - 1.61E+06 - - - -1.2013 - 3.031 0.565 - 1007.9 1 2 0 -0.0019 15 0 0 0 1.39E+08 7.27E+07 - - - 5.9397 1 221125_WJC_METTL3_EV_vs_WT_F03.15768.15768.2 0.00509 14/28 K.VALVYGQMNEPPGAR[166.11].A "sp|P06576|ATPB_HUMAN,tr|F8W0P7|F8W0P7_HUMAN,tr|H0YH81|H0YH81_HUMAN" 3 1610.8114 1.92 31223 15768 2 1610.805432 806.413 "ATP synthase subunit beta, mitochondrial OS=Homo sapiens OX=9606 GN=ATP5F1B PE=1 SV=3" 5.97 2860.4 - 739314 - - - -3.7248 - 2.987 0.557 - 582 1 2 0 -0.006 15 0 0 0 1.39E+08 7.27E+07 - - - 5.8434 1 221125_WJC_METTL3_EV_vs_WT_F03.15769.15769.2 4.44E-05 14/26 K.LVEQLDIEETEQSK.L "sp|Q92552|RT27_HUMAN,tr|G5EA06|G5EA06_HUMAN,tr|D6RH20|D6RH20_HUMAN" 3 1659.8203 1.75 31224 15769 2 1659.820888 830.9174 "28S ribosomal protein S27, mitochondrial OS=Homo sapiens OX=9606 GN=MRPS27 PE=1 SV=3" 3.91 2860.6 - 663519 - - - 0.3476 - 3.017 0.631 - 582 1 2 0 0.0006 14 0 0 0 2.86E+07 1.64E+07 - - - 6.4725 0.9998 221125_WJC_METTL3_EV_vs_WT_F03.15771.15771.2 0.00456 20-Nov R.GVEIC[160.03]IATPGR[166.11].L "sp|Q92841|DDX17_HUMAN,sp|P17844|DDX5_HUMAN,tr|A0A7I2V5F5|A0A7I2V5F5_HUMAN,tr|J3KRZ1|J3KRZ1_HUMAN,tr|J3QSF1|J3QSF1_HUMAN,tr|A0A7I2V507|A0A7I2V507_HUMAN,tr|A0A5H1ZRQ2|A0A5H1ZRQ2_HUMAN,tr|J3KTA4|J3KTA4_HUMAN,tr|A0A0G2JLI4|A0A0G2JLI4_HUMAN,tr|A0A1X7SBZ2|A0A1X7SBZ2_HUMAN,tr|A0A7I2V2S0|A0A7I2V2S0_HUMAN" 11 1181.6102 1.39 31225 15771 2 1181.608072 591.8124 Probable ATP-dependent RNA helicase DDX17 OS=Homo sapiens OX=9606 GN=DDX17 PE=1 SV=2 5.99 2860.8 - 1.19E+07 - - - -1.8119 - 2.276 0.472 - 565.8 1 2 0 -0.0021 11 0 0 0 6.54E+08 4.71E+08 - - - 4.7514 1 221125_WJC_METTL3_EV_vs_WT_F03.15775.15775.2 3.40E-06 26-Dec K.NGIAGSSLPPPPIK.H sp|Q9Y5A9|YTHD2_HUMAN 1 1346.7558 1.43 31228 15775 2 1346.755631 674.3852 YTH domain-containing family protein 2 OS=Homo sapiens OX=9606 GN=YTHDF2 PE=1 SV=2 8.75 2861.2 - 6.78E+06 - - - -0.1262 - 2.649 0.605 - 477.2 1 2 0 -0.0002 14 0 0 0 5.97E+08 4.17E+08 - - - 5.9541 1 221125_WJC_METTL3_EV_vs_WT_F03.15776.15776.2 4.58E-05 13/26 K.NGIAGSSLPPPPIK[136.11].H sp|Q9Y5A9|YTHD2_HUMAN 1 1354.77 1.43 31229 15776 2 1354.771768 678.3923 YTH domain-containing family protein 2 OS=Homo sapiens OX=9606 GN=YTHDF2 PE=1 SV=2 8.75 2861.2 - 3.46E+06 - - - 1.3043 - 2.736 0.578 - 593.8 1 2 0 0.0018 14 0 0 0 5.97E+08 4.17E+08 - - - 5.8353 1 221125_WJC_METTL3_EV_vs_WT_F03.15777.15777.3 1.41E-05 Nov-36 K.EHLMLEEELR.N sp|P15924|DESP_HUMAN 1 1297.6336 1.45 31230 15777 3 1297.633438 433.5518 Desmoplakin OS=Homo sapiens OX=9606 GN=DSP PE=1 SV=3 4.48 2861.3 - 3.22E+06 - - - -0.1534 - 2.498 0.437 - 307.1 1 2 0 -0.0002 10 0 0 0 5.12E+07 3.52E+07 - - - 6.0857 0.9999 221125_WJC_METTL3_EV_vs_WT_F03.15780.15780.3 5.66E-05 15/44 R.LNDSILQATEQR.R sp|P15924|DESP_HUMAN 1 1386.7103 8.13 31233 15780 3 1386.709497 463.244 Desmoplakin OS=Homo sapiens OX=9606 GN=DSP PE=1 SV=3 4.37 2861.7 - 917960 - - - -0.5841 - 2.399 0.424 - 438.9 1 2 0 -0.0008 12 0 0 0 1.32E+07 1.63E+06 - - - 5.6925 0.9962 221125_WJC_METTL3_EV_vs_WT_F03.15782.15782.3 0.207 Dec-52 K.VIASELGSMPELKK.Y "sp|Q9P2J5|SYLC_HUMAN,tr|A0A6I8PIV1|A0A6I8PIV1_HUMAN,tr|A0A6I8PRS0|A0A6I8PRS0_HUMAN,tr|A0A6I8PLB8|A0A6I8PLB8_HUMAN,tr|A0A6I8PIT3|A0A6I8PIT3_HUMAN,tr|A0A6I8PLB3|A0A6I8PLB3_HUMAN,tr|A0A6I8PS05|A0A6I8PS05_HUMAN,tr|B4DER1|B4DER1_HUMAN,tr|A0A6I8PL42|A0A6I8PL42_HUMAN" 9 1500.8222 1.55 31235 15782 3 1500.818174 501.2813 "Leucine--tRNA ligase, cytoplasmic OS=Homo sapiens OX=9606 GN=LARS1 PE=1 SV=2" 6.11 2861.9 - 641329 - - - -2.6599 - 1.794 0.271 - 85.3 1 2 0 -0.004 14 0 0 0 7.81E+06 5.02E+06 - - - 3.1135 0.9992 221125_WJC_METTL3_EV_vs_WT_F03.15787.15787.2 0.0029 16-Aug R.EQVNDLFSR.K "sp|P78347|GTF2I_HUMAN,sp|Q86UP8|GTD2A_HUMAN,sp|Q6EKJ0|GTD2B_HUMAN,tr|A0A494C1N8|A0A494C1N8_HUMAN,tr|A0A087WW90|A0A087WW90_HUMAN,tr|A0A0D9SF80|A0A0D9SF80_HUMAN,tr|A0A494C0I1|A0A494C0I1_HUMAN,tr|A0A494C1K3|A0A494C1K3_HUMAN" 8 1106.5356 1.48 31238 15787 2 1106.535326 554.2751 General transcription factor II-I OS=Homo sapiens OX=9606 GN=GTF2I PE=1 SV=2 4.37 2862.5 - 2.06E+07 - - - -0.2811 - 1.676 0.276 - 386.7 1 2 0 -0.0003 9 0 0 0 1.60E+09 1.08E+09 - - - 2.5734 0.9998 221125_WJC_METTL3_EV_vs_WT_F03.15789.15789.2 1.32E-06 20-Nov R.IPWTAASSQLK.E "sp|Q9GZT3|SLIRP_HUMAN,tr|H0YJW7|H0YJW7_HUMAN,tr|A0A087WUN7|A0A087WUN7_HUMAN,tr|G3V2S9|G3V2S9_HUMAN,tr|H0YJU7|H0YJU7_HUMAN,tr|H0YJ07|H0YJ07_HUMAN,tr|H0YJ40|H0YJ40_HUMAN,tr|G3V4X6|G3V4X6_HUMAN" 8 1200.6503 1.29 31240 15789 2 1200.648992 601.3324 "SRA stem-loop-interacting RNA-binding protein, mitochondrial OS=Homo sapiens OX=9606 GN=SLIRP PE=1 SV=1" 8.75 2862.6 - 5.28E+06 - - - -1.0669 - 2.06 0.494 - 485.2 1 2 0 -0.0013 11 0 0 0 7.54E+07 5.84E+07 - - - 4.6444 0.9999 221125_WJC_METTL3_EV_vs_WT_F03.15790.15790.2 4.09E-05 20-Dec R.IPWTAASSQLK[136.11].E "sp|Q9GZT3|SLIRP_HUMAN,tr|H0YJW7|H0YJW7_HUMAN,tr|A0A087WUN7|A0A087WUN7_HUMAN,tr|G3V2S9|G3V2S9_HUMAN,tr|H0YJU7|H0YJU7_HUMAN,tr|H0YJ07|H0YJ07_HUMAN,tr|H0YJ40|H0YJ40_HUMAN,tr|G3V4X6|G3V4X6_HUMAN" 8 1208.6645 1.36 31241 15790 2 1208.663584 605.3395 "SRA stem-loop-interacting RNA-binding protein, mitochondrial OS=Homo sapiens OX=9606 GN=SLIRP PE=1 SV=1" 8.75 2862.6 - 4.04E+06 - - - -0.7355 - 2.06 0.497 - 585.1 1 2 0 -0.0009 11 0 0 0 7.92E+07 5.84E+07 - - - 4.6667 0.9995 221125_WJC_METTL3_EV_vs_WT_F03.15791.15791.2 0.0022 20-Oct R.NLPLPPPPPPR.G "sp|P61978|HNRPK_HUMAN,tr|Q5T6W2|Q5T6W2_HUMAN" 2 1193.6921 2.01 31242 15791 2 1193.690521 597.8533 Heterogeneous nuclear ribonucleoprotein K OS=Homo sapiens OX=9606 GN=HNRNPK PE=1 SV=1 9.75 2862.7 - 2.82E+06 - - - -1.3044 - 1.799 0.367 - 301.7 1 2 0 -0.0016 11 0 0 0 1.74E+08 8.67E+07 - - - 3.3398 0.9995 221125_WJC_METTL3_EV_vs_WT_F03.15792.15792.2 0.00107 16-Sep K.EGEFVAQFK[136.11].F sp|Q9UQ80|PA2G4_HUMAN 1 1061.5273 0.28 31243 15792 2 1061.525965 531.7709 Proliferation-associated protein 2G4 OS=Homo sapiens OX=9606 GN=PA2G4 PE=1 SV=3 4.53 2862.7 - 2.15E+06 - - - -1.268 - 1.533 0.422 - 277.2 1 2 0 -0.0013 9 0 0 0 6.72E+06 2.37E+07 - - - 3.3935 0.9999 221125_WJC_METTL3_EV_vs_WT_F03.15794.15794.2 2.44E-06 20-Aug K.YGQISEVVVVK[136.11].D "sp|Q14011|CIRBP_HUMAN,tr|K7ER40|K7ER40_HUMAN,tr|K7ENX8|K7ENX8_HUMAN,tr|K7EJV1|K7EJV1_HUMAN,tr|K7EJV5|K7EJV5_HUMAN,tr|K7ELT6|K7ELT6_HUMAN,tr|K7EMY9|K7EMY9_HUMAN,tr|K7ELV6|K7ELV6_HUMAN,tr|K7EQR7|K7EQR7_HUMAN,tr|K7EPM4|K7EPM4_HUMAN,tr|D6W5Y5|D6W5Y5_HUMAN" 11 1227.6954 0.94 31245 15794 2 1227.694632 614.855 Cold-inducible RNA-binding protein OS=Homo sapiens OX=9606 GN=CIRBP PE=1 SV=1 6 2862.9 - 1.75E+06 - - - -0.6573 - 2.078 0.534 - 176.9 1 2 0 -0.0008 11 0 0 0 1.30E+08 1.38E+08 - - - 4.9635 0.9796 221125_WJC_METTL3_EV_vs_WT_F03.15795.15795.2 0.11 24-Dec R.LTADLSAETLQAR[166.11].R sp|Q9UN81|LORF1_HUMAN 1 1397.739 0.02 31246 15795 2 1397.745282 699.8768 LINE-1 retrotransposable element ORF1 protein OS=Homo sapiens OX=9606 GN=L1RE1 PE=1 SV=1 4.37 2862.9 - 1.71E+06 - - - 4.5101 - 1.644 0.232 - 378.7 1 2 0 0.0063 13 0 0 0 4.95E+05 1.99E+07 - - - 2.0285 0.9996 221125_WJC_METTL3_EV_vs_WT_F03.15796.15796.2 0.000455 16-Aug R.GDDQLELIK.D "sp|P07910|HNRPC_HUMAN,sp|O60812|HNRC1_HUMAN,tr|G3V5V7|G3V5V7_HUMAN,tr|B2R5W2|B2R5W2_HUMAN,tr|G3V4C1|G3V4C1_HUMAN,tr|G3V2D6|G3V2D6_HUMAN,tr|G3V2Q1|G3V2Q1_HUMAN" 7 1029.5342 1.48 31247 15796 2 1029.533159 515.7744 Heterogeneous nuclear ribonucleoproteins C1\C2 OS=Homo sapiens OX=9606 GN=HNRNPC PE=1 SV=4 4.03 2863 - 1.66E+06 - - - -1.05 - 1.622 0.404 - 204 1 2 0 -0.0011 9 0 0 0 1.71E+07 1.16E+07 - - - 3.4239 0.9983 221125_WJC_METTL3_EV_vs_WT_F03.15797.15797.3 0.00375 Jul-36 R.VESHFDLELR.A "sp|Q6P2Q9|PRP8_HUMAN,tr|I3L0J9|I3L0J9_HUMAN" 2 1243.6197 1.21 31248 15797 3 1243.6195 415.5472 Pre-mRNA-processing-splicing factor 8 OS=Homo sapiens OX=9606 GN=PRPF8 PE=1 SV=2 4.65 2863.1 - 1.37E+06 - - - -0.1616 - 1.702 0.256 - 69.1 1 2 0 -0.0002 10 0 0 0 1.29E+07 1.07E+07 - - - 2.9472 0.9998 221125_WJC_METTL3_EV_vs_WT_F03.15799.15799.3 0.00477 14/56 K.VALVYGQMNEPPGAR[166.11].A "sp|P06576|ATPB_HUMAN,tr|F8W0P7|F8W0P7_HUMAN,tr|H0YH81|H0YH81_HUMAN" 3 1610.8114 1.9 31250 15799 3 1610.810141 537.9444 "ATP synthase subunit beta, mitochondrial OS=Homo sapiens OX=9606 GN=ATP5F1B PE=1 SV=3" 5.97 2863.2 - 2.11E+06 - - - -0.8015 - 1.971 0.39 - 194.5 1 2 0 -0.0013 15 0 0 0 5.38E+07 2.82E+07 - - - 4.6583 0.9986 221125_WJC_METTL3_EV_vs_WT_F03.15800.15800.2 4.60E-05 13/24 R.VQNMALYADVGGK[136.11].Q sp|P51571|SSRD_HUMAN 1 1372.69 1.18 31251 15800 2 1372.696386 687.3523 Translocon-associated protein subunit delta OS=Homo sapiens OX=9606 GN=SSR4 PE=1 SV=1 5.81 2863.3 - 1.12E+06 - - - 4.626 - 2.744 0.501 - 731.3 1 2 0 0.0063 13 0 0 0 6.68E+07 5.68E+07 - - - 5.3301 0.9893 221125_WJC_METTL3_EV_vs_WT_F03.15801.15801.2 5.98E-07 22-Dec Y.SEFILATGSADK.T "sp|Q09028|RBBP4_HUMAN,sp|Q16576|RBBP7_HUMAN,tr|H0YCT5|H0YCT5_HUMAN,tr|H0YDK2|H0YDK2_HUMAN,tr|Q5JP02|Q5JP02_HUMAN,tr|H0YEU5|H0YEU5_HUMAN,tr|Q5JP01|Q5JP01_HUMAN,tr|H0YF10|H0YF10_HUMAN,tr|E9PC52|E9PC52_HUMAN" 9 1237.619 6.58 31252 15801 2 1237.617577 619.8168 Histone-binding protein RBBP4 OS=Homo sapiens OX=9606 GN=RBBP4 PE=1 SV=3 4.37 2863.4 - 1.01E+06 - - - -1.1765 - 2.422 0.44 - 611.1 1 1 0 -0.0015 12 0 0 0 8.70E+06 1.32E+06 - - - 4.6179 1 221125_WJC_METTL3_EV_vs_WT_F03.15802.15802.3 7.87E-05 Nov-36 R.VESHFDLELR[166.11].A "sp|Q6P2Q9|PRP8_HUMAN,tr|I3L0J9|I3L0J9_HUMAN" 2 1253.628 1.3 31253 15802 3 1253.627547 418.8833 Pre-mRNA-processing-splicing factor 8 OS=Homo sapiens OX=9606 GN=PRPF8 PE=1 SV=2 4.65 2863.5 - 874052 - - - -0.3382 - 2.059 0.484 - 192.8 1 2 0 -0.0004 10 0 0 0 1.31E+07 1.01E+07 - - - 6.0452 0.9997 221125_WJC_METTL3_EV_vs_WT_F03.15803.15803.2 0.000132 18-Nov K.NSFQPISSLR[166.11].D sp|P98175|RBM10_HUMAN 1 1157.6068 2.54 31254 15803 2 1157.605229 579.8107 RNA-binding protein 10 OS=Homo sapiens OX=9606 GN=RBM10 PE=1 SV=3 9.75 2863.6 - 510556 - - - -1.3934 - 1.817 0.437 - 391.8 1 2 0 -0.0016 10 0 0 0 1.41E+08 5.57E+07 - - - 3.9351 0.9979 221125_WJC_METTL3_EV_vs_WT_F03.15807.15807.2 0.214 14-Jul K.SAFPFSDK.L sp|Q14677|EPN4_HUMAN 1 897.4232 1.48 31256 15807 2 897.42227 449.7189 Clathrin interactor 1 OS=Homo sapiens OX=9606 GN=CLINT1 PE=1 SV=1 5.55 2864.1 - 1.98E+07 - - - -1.0731 - 1.403 0.252 - 149.7 1 2 0 -0.001 8 0 0 0 5.47E+08 3.70E+08 - - - 1.9232 0.9997 221125_WJC_METTL3_EV_vs_WT_F03.15811.15811.2 0.0256 16-Sep K.TLLDIDNTR.M sp|P35527|K1C9_HUMAN 1 1059.556 5980.91 31260 15811 2 1059.55611 530.7853 "Keratin, type I cytoskeletal 9 OS=Homo sapiens OX=9606 GN=KRT9 PE=1 SV=3" 4.21 2864.3 - 4.68E+06 - - - 0.068 - 1.694 0.417 - 238.2 1 2 0 0.0001 9 0 0 0 6.02E+09 1.01E+06 - - - 3.6458 0.9999 221125_WJC_METTL3_EV_vs_WT_F03.15812.15812.2 0.000181 20-Sep K.YGQISEVVVVK.D "sp|Q14011|CIRBP_HUMAN,tr|K7ER40|K7ER40_HUMAN,tr|K7ENX8|K7ENX8_HUMAN,tr|K7EJV1|K7EJV1_HUMAN,tr|K7EJV5|K7EJV5_HUMAN,tr|K7ELT6|K7ELT6_HUMAN,tr|K7EMY9|K7EMY9_HUMAN,tr|K7ELV6|K7ELV6_HUMAN,tr|K7EQR7|K7EQR7_HUMAN,tr|K7EPM4|K7EPM4_HUMAN,tr|D6W5Y5|D6W5Y5_HUMAN" 11 1219.6812 0.94 31261 15812 2 1219.680929 610.8479 Cold-inducible RNA-binding protein OS=Homo sapiens OX=9606 GN=CIRBP PE=1 SV=1 6 2864.4 - 3.19E+06 - - - -0.2542 - 2.1 0.505 - 251.8 1 2 0 -0.0003 11 0 0 0 1.30E+08 1.38E+08 - - - 4.7779 0.9998 221125_WJC_METTL3_EV_vs_WT_F03.15815.15815.2 0.000396 18-Nov K.NSFQPISSLR.D sp|P98175|RBM10_HUMAN 1 1147.5986 2.56 31264 15815 2 1147.598481 574.8066 RNA-binding protein 10 OS=Homo sapiens OX=9606 GN=RBM10 PE=1 SV=3 9.75 2864.6 - 1.66E+06 - - - -0.0793 - 2.013 0.459 - 446.3 1 2 0 -0.0001 10 0 0 0 1.42E+08 5.57E+07 - - - 4.384 0.9996 221125_WJC_METTL3_EV_vs_WT_F03.15817.15817.2 0.0147 18-Jul R.NLVDNITGQR.L "sp|Q15149|PLEC_HUMAN,tr|H0YDN1|H0YDN1_HUMAN" 2 1128.5887 2.34 31266 15817 2 1128.589179 565.3016 Plectin OS=Homo sapiens OX=9606 GN=PLEC PE=1 SV=3 5.84 2864.7 - 1.60E+06 - - - 0.3925 - 1.757 0.357 - 134 1 2 0 0.0004 10 0 0 0 1.79E+07 7.66E+06 - - - 3.2509 0.9804 221125_WJC_METTL3_EV_vs_WT_F03.15820.15820.2 0.000156 14-Aug L.LQDFFNGK[136.11].E "sp|P54652|HSP72_HUMAN,sp|P11142|HSP7C_HUMAN,sp|P17066|HSP76_HUMAN,tr|E9PNE6|E9PNE6_HUMAN,tr|A8K7Q2|A8K7Q2_HUMAN,tr|E9PKE3|E9PKE3_HUMAN,tr|E9PN89|E9PN89_HUMAN" 7 975.4905 0.13 31269 15820 2 975.489414 488.7525 Heat shock-related 70 kDa protein 2 OS=Homo sapiens OX=9606 GN=HSPA2 PE=1 SV=1 5.84 2865 - 1.07E+06 - - - -1.1451 - 1.769 0.404 - 169.8 1 1 0 -0.0011 8 0 0 0 2.44E+06 1.91E+07 - - - 3.7449 0.9999 221125_WJC_METTL3_EV_vs_WT_F03.15821.15821.2 1.11E-05 13/26 K.TPVTQVNEVTGTLR.L "sp|Q13405|RM49_HUMAN,tr|H0YDP7|H0YDP7_HUMAN" 2 1513.81 0.81 31270 15821 2 1513.808569 757.9123 "39S ribosomal protein L49, mitochondrial OS=Homo sapiens OX=9606 GN=MRPL49 PE=1 SV=1" 5.66 2865.1 - 1.06E+06 - - - -0.9592 - 2.75 0.465 - 375.9 1 2 0 -0.0015 14 0 0 0 2.62E+07 3.26E+07 - - - 5.0136 0.9999 221125_WJC_METTL3_EV_vs_WT_F03.15822.15822.2 1.34E-06 22-Nov K.FVTDSNAVVQLK[136.11].G "sp|Q14008|CKAP5_HUMAN,tr|E9PQH5|E9PQH5_HUMAN" 2 1327.7227 0.44 31271 15822 2 1327.720923 664.8686 Cytoskeleton-associated protein 5 OS=Homo sapiens OX=9606 GN=CKAP5 PE=1 SV=3 5.84 2865.2 - 939243 - - - -1.3504 - 2.4 0.549 - 227.7 1 2 0 -0.0018 12 0 0 0 4.01E+06 9.13E+06 - - - 5.3989 0.9862 221125_WJC_METTL3_EV_vs_WT_F03.15823.15823.2 0.118 14-Sep R.SEQFINLR[166.11].E sp|P07384|CAN1_HUMAN 1 1015.5326 1.17 31272 15823 2 1015.536178 508.7736 Calpain-1 catalytic subunit OS=Homo sapiens OX=9606 GN=CAPN1 PE=1 SV=1 5.72 2865.3 - 812244 - - - 3.5095 - 1.499 0.202 - 234.9 1 2 0 0.0036 8 0 0 0 2.01E+07 1.72E+07 - - - 1.7527 0.9546 221125_WJC_METTL3_EV_vs_WT_F03.15824.15824.2 0.19 24-Nov R.VLGQVSC[160.03]ELVSPK.L "sp|Q06265|EXOS9_HUMAN,tr|D6RAP4|D6RAP4_HUMAN,tr|D6R905|D6R905_HUMAN,tr|D6RA17|D6RA17_HUMAN,tr|D6RIY6|D6RIY6_HUMAN" 5 1414.749 0.58 31273 15824 2 1414.756592 708.3818 Exosome complex component RRP45 OS=Homo sapiens OX=9606 GN=EXOSC9 PE=1 SV=3 5.97 2865.5 - 809331 - - - 5.3656 - 1.636 0.21 - 242.5 1 2 0 0.0076 13 0 0 0 4.62E+06 7.96E+06 - - - 1.8531 0.9995 221125_WJC_METTL3_EV_vs_WT_F03.15825.15825.2 3.82E-05 20-Nov K.DTDEADLVLAK.E sp|P45973|CBX5_HUMAN 1 1188.5874 0.41 31274 15825 2 1188.589982 595.301 Chromobox protein homolog 5 OS=Homo sapiens OX=9606 GN=CBX5 PE=1 SV=1 3.84 2865.6 - 796048 - - - 2.174 - 2.042 0.425 - 343.7 1 2 0 0.0026 11 0 0 0 7.39E+06 1.82E+07 - - - 4.1106 0.9992 221125_WJC_METTL3_EV_vs_WT_F03.15826.15826.2 0.00119 14-Sep R.SEQFINLR.E sp|P07384|CAN1_HUMAN 1 1005.5243 1.17 31275 15826 2 1005.522621 503.7694 Calpain-1 catalytic subunit OS=Homo sapiens OX=9606 GN=CAPN1 PE=1 SV=1 5.72 2865.7 - 790236 - - - -1.7135 - 1.725 0.334 - 441.5 1 2 0 -0.0017 8 0 0 0 2.03E+07 1.73E+07 - - - 3.1518 0.9991 221125_WJC_METTL3_EV_vs_WT_F03.15830.15830.2 0.0693 14-Jul K.SAFPFSDK[136.11].L sp|Q14677|EPN4_HUMAN 1 905.4374 1.63 31278 15830 2 905.43654 453.726 Clathrin interactor 1 OS=Homo sapiens OX=9606 GN=CLINT1 PE=1 SV=1 5.55 2866.1 - 1.09E+07 - - - -0.9863 - 1.594 0.298 - 155.6 1 2 0 -0.0009 8 0 0 0 3.77E+08 2.31E+08 - - - 2.6479 1 221125_WJC_METTL3_EV_vs_WT_F03.15834.15834.2 1.95E-09 15/26 K.TPVTQVNEVTGTLR[166.11].L "sp|Q13405|RM49_HUMAN,tr|H0YDP7|H0YDP7_HUMAN" 2 1523.8183 1.32 31282 15834 2 1523.821162 762.9164 "39S ribosomal protein L49, mitochondrial OS=Homo sapiens OX=9606 GN=MRPL49 PE=1 SV=1" 5.66 2866.4 - 814174 - - - 1.8841 - 3.048 0.565 - 426.8 1 2 0 0.0029 14 0 0 0 2.49E+07 1.89E+07 - - - 6.0099 0.9995 221125_WJC_METTL3_EV_vs_WT_F03.15835.15835.2 0.00212 26-Jul K.LVRPPVQVYGIEGR.Y "sp|P48047|ATPO_HUMAN,tr|H7C086|H7C086_HUMAN,tr|H7C0C1|H7C0C1_HUMAN,tr|A0A494C0K9|A0A494C0K9_HUMAN" 4 1581.8991 1.08 31283 15835 2 1581.89996 791.9568 "ATP synthase subunit O, mitochondrial OS=Homo sapiens OX=9606 GN=ATP5PO PE=1 SV=1" 8.75 2866.5 - 611897 - - - 0.5367 - 1.464 0.426 - 38.1 1 2 0 0.0008 14 0 0 0 8.38E+06 7.74E+06 - - - 3.1437 0.9998 221125_WJC_METTL3_EV_vs_WT_F03.15838.15838.2 2.46E-07 Oct-32 K.GFATSSYYPPAGGGYGR.A sp|P17509|HXB6_HUMAN 1 1706.7689 3.74 31286 15838 2 1706.766138 854.3917 Homeobox protein Hox-B6 OS=Homo sapiens OX=9606 GN=HOXB6 PE=1 SV=4 8.5 2866.9 - 300845 - - - -1.6095 - 2.056 0.609 - 175.6 1 2 0 -0.0027 17 0 0 0 4.15E+06 1.11E+06 - - - 5.3102 0.9998 221125_WJC_METTL3_EV_vs_WT_F03.15839.15839.2 8.15E-05 15/24 K.WAAVVVPSGEEQR[166.11].Y "sp|P01889|HLAB_HUMAN,sp|P13747|HLAE_HUMAN,sp|P04439|HLAA_HUMAN,sp|P01893|HLAH_HUMAN,sp|P17693|HLAG_HUMAN,tr|A0A1W2PP77|A0A1W2PP77_HUMAN,tr|A0A1W2PNZ7|A0A1W2PNZ7_HUMAN,tr|A0A0G2JI36|A0A0G2JI36_HUMAN,tr|A0A140T951|A0A140T951_HUMAN,tr|Q53YP1|Q53YP1_HUMAN,tr|Q5RIP0|Q5RIP0_HUMAN,tr|Q5SRN5|Q5SRN5_HUMAN,tr|A0A1W2PS24|A0A1W2PS24_HUMAN,tr|A0A0G2JIF2|A0A0G2JIF2_HUMAN,tr|D0EV57|D0EV57_HUMAN,tr|A0A140T9V0|A0A140T9V0_HUMAN,tr|Q2L6G2|Q2L6G2_HUMAN,tr|A0A1W2PQD0|A0A1W2PQD0_HUMAN,tr|A0A1W2PRZ0|A0A1W2PRZ0_HUMAN,tr|Q8MH48|Q8MH48_HUMAN,tr|A0A0G2JH50|A0A0G2JH50_HUMAN,tr|A0A0G2JNX1|A0A0G2JNX1_HUMAN,tr|A0A140T9U0|A0A140T9U0_HUMAN,tr|A0A140T9W2|A0A140T9W2_HUMAN,tr|O78179|O78179_HUMAN,tr|D5H3J5|D5H3J5_HUMAN,tr|S6AU73|S6AU73_HUMAN,tr|A0A140T9B7|A0A140T9B7_HUMAN,tr|Q5SUL5|Q5SUL5_HUMAN,tr|A0A140T939|A0A140T939_HUMAN,tr|A0A140T9W7|A0A140T9W7_HUMAN,tr|A2BF26|A2BF26_HUMAN,tr|A0A0G2JPA3|A0A0G2JPA3_HUMAN,tr|A0A1W2PS56|A0A1W2PS56_HUMAN,tr|A0A140T9W3|A0A140T9W3_HUMAN,tr|A0A140T9D9|A0A140T9D9_HUMAN,tr|A0A0G2JIF0|A0A0G2JIF0_HUMAN,tr|A0A1W2PSE7|A0A1W2PSE7_HUMAN,tr|A0A0G2JH66|A0A0G2JH66_HUMAN,tr|Q5QT33|Q5QT33_HUMAN,tr|Q5RJ85|Q5RJ85_HUMAN,tr|A0A140T9J9|A0A140T9J9_HUMAN,tr|A0A0G2JPQ3|A0A0G2JPQ3_HUMAN,tr|A0A140T9G0|A0A140T9G0_HUMAN,tr|A0A140T9H3|A0A140T9H3_HUMAN,tr|A0A140T9B3|A0A140T9B3_HUMAN,tr|A0A140T9X6|A0A140T9X6_HUMAN,tr|Q5SS57|Q5SS57_HUMAN,tr|D9J307|D9J307_HUMAN,tr|A0A140T8X0|A0A140T8X0_HUMAN,tr|A0A1W2PRX1|A0A1W2PRX1_HUMAN,tr|A0A140T9C2|A0A140T9C2_HUMAN,tr|A0A140T9A9|A0A140T9A9_HUMAN,tr|A0A140T937|A0A140T937_HUMAN,tr|Q5SRN7|Q5SRN7_HUMAN,tr|A0A140T912|A0A140T912_HUMAN,tr|A0A140T962|A0A140T962_HUMAN,tr|A0A140T9M0|A0A140T9M0_HUMAN,tr|A0A140T9S9|A0A140T9S9_HUMAN,tr|A0A1W2PR11|A0A1W2PR11_HUMAN,tr|A0A140T930|A0A140T930_HUMAN,tr|Q31611|Q31611_HUMAN,tr|A0A0G2JL56|A0A0G2JL56_HUMAN" 63 1436.7287 1.31 31287 15839 2 1436.72544 719.3717 "HLA class I histocompatibility antigen, B alpha chain OS=Homo sapiens OX=9606 GN=HLA-B PE=1 SV=3" 4.53 2867.1 - 280988 - - - -2.3025 - 3.029 0.506 - 877.4 1 2 0 -0.0033 13 0 0 0 6.37E+06 4.87E+06 - - - 5.6216 0.9994 221125_WJC_METTL3_EV_vs_WT_F03.15840.15840.2 0.000401 Aug-32 K.NVGTGLVGAPAC[160.03]GDVMK[136.11].L "sp|Q9H1K1|ISCU_HUMAN,tr|B3KQ30|B3KQ30_HUMAN,tr|B4DNC9|B4DNC9_HUMAN,tr|F5H5N2|F5H5N2_HUMAN" 4 1652.8106 0.65 31288 15840 2 1652.814025 827.4126 "Iron-sulfur cluster assembly enzyme ISCU, mitochondrial OS=Homo sapiens OX=9606 GN=ISCU PE=1 SV=2" 5.83 2867.2 - 261162 - - - 2.0952 - 1.762 0.465 - 113.1 1 2 0 0.0035 17 0 0 0 1.23E+06 1.88E+06 - - - 3.867 0.9999 221125_WJC_METTL3_EV_vs_WT_F03.15844.15844.2 4.54E-06 24-Dec K.LYIVGGSDPYGQK.G sp|Q9Y6Y0|NS1BP_HUMAN 1 1395.7034 1.8 31290 15844 2 1395.703983 698.859 Influenza virus NS1A-binding protein OS=Homo sapiens OX=9606 GN=IVNS1ABP PE=1 SV=3 5.83 2867.7 - 1.71E+06 - - - 0.3955 - 2.188 0.536 - 422.3 1 2 0 0.0006 13 0 0 0 1.69E+07 9.37E+06 - - - 5.0093 0.9997 221125_WJC_METTL3_EV_vs_WT_F03.15845.15845.2 0.000168 16-Sep K.WQNNLLPSR[166.11].Q "sp|P62244|RS15A_HUMAN,tr|I3L3P7|I3L3P7_HUMAN,tr|H3BVC7|H3BVC7_HUMAN" 3 1136.5966 0.8 31291 15845 2 1136.597655 569.3056 40S ribosomal protein S15a OS=Homo sapiens OX=9606 GN=RPS15A PE=1 SV=2 9.75 2867.7 - 2.51E+06 - - - 0.9177 - 1.679 0.442 - 314.1 1 2 0 0.001 9 0 0 0 6.10E+08 7.59E+08 - - - 3.8045 0.9994 221125_WJC_METTL3_EV_vs_WT_F03.15848.15848.3 0.00116 Nov-44 K.WQTMIEAHVDVK.T "sp|P61247|RS3A_HUMAN,tr|H0Y8L7|H0Y8L7_HUMAN,tr|D6RED7|D6RED7_HUMAN,tr|D6RAS7|D6RAS7_HUMAN,tr|D6RB09|D6RB09_HUMAN,tr|E9PFI5|E9PFI5_HUMAN,tr|D6RAT0|D6RAT0_HUMAN,tr|D6RG13|D6RG13_HUMAN" 8 1455.718 0.87 31294 15848 3 1455.715597 486.2466 40S ribosomal protein S3a OS=Homo sapiens OX=9606 GN=RPS3A PE=1 SV=2 5.32 2868.1 - 676172 - - - -1.6748 - 2.047 0.305 - 139.3 1 2 0 -0.0024 12 0 0 0 9.59E+06 1.11E+07 - - - 3.9255 0.9465 221125_WJC_METTL3_EV_vs_WT_F03.15849.15849.3 0.0443 Nov-36 S.ISPAFLHLNK.A "sp|Q9HCJ3|RAVR2_HUMAN,tr|E9PE10|E9PE10_HUMAN" 2 1138.6499 0.64 31295 15849 3 1138.646876 380.5572 Ribonucleoprotein PTB-binding 2 OS=Homo sapiens OX=9606 GN=RAVER2 PE=1 SV=2 8.76 2868.2 - 628535 - - - -2.6373 - 2.199 0.339 - 89 1 1 0 -0.003 10 0 0 0 4.33E+06 6.81E+06 - - - 4.62 0.9999 221125_WJC_METTL3_EV_vs_WT_F03.15854.15854.2 7.84E-05 13/24 K.GTIQVITQGTSLK[136.11].N "sp|O43175|SERA_HUMAN,tr|A0A2C9F2M7|A0A2C9F2M7_HUMAN,tr|A0A286YF22|A0A286YF22_HUMAN" 3 1352.7755 1.24 31298 15854 2 1352.775094 677.395 D-3-phosphoglycerate dehydrogenase OS=Homo sapiens OX=9606 GN=PHGDH PE=1 SV=4 8.75 2868.9 - 1.31E+07 - - - -0.2853 - 2.687 0.503 - 653.9 1 2 0 -0.0004 13 0 0 0 2.52E+08 2.03E+08 - - - 5.2929 0.9997 221125_WJC_METTL3_EV_vs_WT_F03.15859.15859.3 0.275 14/40 R.NLPLPPPPPPR.G "sp|P61978|HNRPK_HUMAN,tr|Q5T6W2|Q5T6W2_HUMAN" 2 1193.6921 1.55 31303 15859 3 1193.693263 398.9046 Heterogeneous nuclear ribonucleoprotein K OS=Homo sapiens OX=9606 GN=HNRNPK PE=1 SV=1 9.75 2869.5 - 622740 - - - 0.9927 - 2.862 0.25 - 281.6 1 2 0 0.0012 11 0 0 0 6.56E+06 4.23E+06 - - - 4.3141 0.9999 221125_WJC_METTL3_EV_vs_WT_F03.15860.15860.3 0.00129 13/36 R.LILEVHQFSR.D "sp|Q01082|SPTB2_HUMAN,tr|A0A087WUZ3|A0A087WUZ3_HUMAN" 2 1240.6928 1.52 31304 15860 3 1240.691503 414.5715 "Spectrin beta chain, non-erythrocytic 1 OS=Homo sapiens OX=9606 GN=SPTBN1 PE=1 SV=2" 6.75 2869.6 - 572108 - - - -1.051 - 2.39 0.426 - 214 1 2 0 -0.0013 10 0 0 0 2.97E+07 1.95E+07 - - - 5.8337 0.9997 221125_WJC_METTL3_EV_vs_WT_F03.15861.15861.2 5.55E-06 26-Nov R.LVVPASQC[160.03]GSLIGK[136.11].G "sp|P57721|PCBP3_HUMAN,sp|Q15366|PCBP2_HUMAN,tr|F8W1G6|F8W1G6_HUMAN,tr|E9PFP8|E9PFP8_HUMAN,tr|J3QT27|J3QT27_HUMAN,tr|F8VZX2|F8VZX2_HUMAN,tr|F8W0G4|F8W0G4_HUMAN,tr|F8VXH9|F8VXH9_HUMAN,tr|H3BRU6|H3BRU6_HUMAN,tr|H3BND9|H3BND9_HUMAN" 10 1435.7948 1.12 31305 15861 2 1435.795224 718.9047 Poly(rC)-binding protein 3 OS=Homo sapiens OX=9606 GN=PCBP3 PE=1 SV=2 8.22 2869.8 - 478598 - - - 0.2702 - 2.014 0.41 - 248.6 1 2 0 0.0004 14 0 0 0 3.34E+08 2.97E+08 - - - 3.8261 0.9999 221125_WJC_METTL3_EV_vs_WT_F03.15866.15866.2 3.14E-05 16-Aug R.DDGVDYWAK[136.11].R "sp|Q9NYF8|BCLF1_HUMAN,tr|H0YF63|H0YF63_HUMAN,tr|E9PK91|E9PK91_HUMAN,tr|H0YF14|H0YF14_HUMAN" 4 1075.4702 2.11 31308 15866 2 1075.469341 538.7424 Bcl-2-associated transcription factor 1 OS=Homo sapiens OX=9606 GN=BCLAF1 PE=1 SV=2 3.93 2870.4 - 2.19E+06 - - - -0.7894 - 1.748 0.555 - 325.2 1 2 0 -0.0008 9 0 0 0 1.17E+08 5.55E+07 - - - 4.7557 0.9992 221125_WJC_METTL3_EV_vs_WT_F03.15867.15867.2 0.00201 20-Sep K.NNIPYFETSAK.E "sp|P51149|RAB7A_HUMAN,tr|C9J4V0|C9J4V0_HUMAN,tr|A0A6Q8PH84|A0A6Q8PH84_HUMAN,tr|C9J8S3|C9J8S3_HUMAN,tr|A0A6Q8PGE6|A0A6Q8PGE6_HUMAN,tr|A0A6Q8PG52|A0A6Q8PG52_HUMAN" 6 1282.6194 1.26 31309 15867 2 1282.61669 642.317 Ras-related protein Rab-7a OS=Homo sapiens OX=9606 GN=RAB7A PE=1 SV=1 6 2870.5 - 833007 - - - -2.0871 - 1.822 0.365 - 227.6 1 2 0 -0.0027 11 0 0 0 1.36E+07 1.08E+07 - - - 3.359 0.9983 221125_WJC_METTL3_EV_vs_WT_F03.15878.15878.3 2.90E-07 16/48 K.R[166.11]GLLQDDAHPTLV.T "sp|Q86U44|MTA70_HUMAN,tr|F5H6D8|F5H6D8_HUMAN,tr|H0YFV6|H0YFV6_HUMAN,tr|B4DTN4|B4DTN4_HUMAN" 4 1443.7709 0.04 31318 15878 3 1443.770498 482.2643 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 5.21 2871.8 - 2.49E+06 - - - -0.311 - 2.715 0.55 - 345.4 1 1 0 -0.0004 13 0 0 0 4.02E+06 1.06E+08 - - - 7.3798 1 221125_WJC_METTL3_EV_vs_WT_F03.15879.15879.2 6.00E-08 15/22 K.LVTDQNISENWR[166.11].V "sp|P24666|PPAC_HUMAN,tr|F2Z2Q9|F2Z2Q9_HUMAN,tr|G5E9R5|G5E9R5_HUMAN" 3 1483.7295 1 31319 15879 2 1483.728833 742.872 Low molecular weight phosphotyrosine protein phosphatase OS=Homo sapiens OX=9606 GN=ACP1 PE=1 SV=3 4.37 2871.9 - 1.67E+06 - - - -0.4334 - 2.885 0.566 - 837.3 1 2 0 -0.0006 12 0 0 0 1.19E+08 1.19E+08 - - - 6.0091 0.9998 221125_WJC_METTL3_EV_vs_WT_F03.15880.15880.2 0.00108 18-Dec K.DAGGMVIDMK.W "sp|P35658|NU214_HUMAN,tr|A0A494BZU9|A0A494BZU9_HUMAN,tr|A0A494C1F2|A0A494C1F2_HUMAN,tr|A0A494C0J0|A0A494C0J0_HUMAN" 4 1035.4729 2.48 31320 15880 2 1035.473633 518.7437 Nuclear pore complex protein Nup214 OS=Homo sapiens OX=9606 GN=NUP214 PE=1 SV=2 4.21 2872.1 - 1.64E+06 - - - 0.706 - 2.295 0.363 - 485.4 1 2 0 0.0007 10 0 0 0 2.52E+07 1.02E+07 - - - 4.0407 1 221125_WJC_METTL3_EV_vs_WT_F03.15882.15882.2 6.04E-07 16/22 K.LVTDQNISENWR.V "sp|P24666|PPAC_HUMAN,tr|F2Z2Q9|F2Z2Q9_HUMAN,tr|G5E9R5|G5E9R5_HUMAN" 3 1473.7212 1 31322 15882 2 1473.721117 737.8679 Low molecular weight phosphotyrosine protein phosphatase OS=Homo sapiens OX=9606 GN=ACP1 PE=1 SV=3 4.37 2872.3 - 1.48E+06 - - - -0.0604 - 2.661 0.581 - 958 1 2 0 -0.0001 12 0 0 0 1.19E+08 1.19E+08 - - - 5.9074 0.9968 221125_WJC_METTL3_EV_vs_WT_F03.15883.15883.3 0.00161 13/36 R.LILEVHQFSR[166.11].D "sp|Q01082|SPTB2_HUMAN,tr|A0A087WUZ3|A0A087WUZ3_HUMAN" 2 1250.7011 1.52 31323 15883 3 1250.693798 417.9076 "Spectrin beta chain, non-erythrocytic 1 OS=Homo sapiens OX=9606 GN=SPTBN1 PE=1 SV=2" 6.75 2872.3 - 1.25E+06 - - - -5.8199 - 2.381 0.361 - 296.6 1 2 0 -0.0073 10 0 0 0 2.97E+07 1.95E+07 - - - 5.0963 0.9998 221125_WJC_METTL3_EV_vs_WT_F03.15887.15887.2 0.00169 22-Nov K.LGSIAIQGAIEK.A "sp|P24752|THIL_HUMAN,tr|A0A5F9ZHL7|A0A5F9ZHL7_HUMAN,tr|A0A5F9ZHJ7|A0A5F9ZHJ7_HUMAN,tr|A0A5F9ZHH9|A0A5F9ZHH9_HUMAN,tr|A0A5F9ZHL1|A0A5F9ZHL1_HUMAN,tr|E9PRQ6|E9PRQ6_HUMAN,tr|H0YEL7|H0YEL7_HUMAN" 7 1198.6921 1.18 31327 15887 2 1198.692189 600.3533 "Acetyl-CoA acetyltransferase, mitochondrial OS=Homo sapiens OX=9606 GN=ACAT1 PE=1 SV=1" 6 2872.8 - 968161 - - - 0.0425 - 2.412 0.401 - 283.9 1 2 0 0.0001 12 0 0 0 6.35E+07 5.40E+07 - - - 4.3194 0.9998 221125_WJC_METTL3_EV_vs_WT_F03.15894.15894.2 4.72E-05 16-Sep R.DDGVDYWAK.R "sp|Q9NYF8|BCLF1_HUMAN,tr|H0YF63|H0YF63_HUMAN,tr|E9PK91|E9PK91_HUMAN,tr|H0YF14|H0YF14_HUMAN" 4 1067.456 2.11 31332 15894 2 1067.454035 534.7353 Bcl-2-associated transcription factor 1 OS=Homo sapiens OX=9606 GN=BCLAF1 PE=1 SV=2 3.93 2873.6 - 9.36E+06 - - - -1.8315 - 1.953 0.56 - 449.2 1 2 0 -0.002 9 0 0 0 1.17E+08 5.55E+07 - - - 5.1131 1 221125_WJC_METTL3_EV_vs_WT_F03.15895.15895.2 1.12E-06 18/30 R.TALASGGVLDASGDYR.V sp|O43505|B4GA1_HUMAN 1 1551.7529 1.45 31333 15895 2 1551.752473 776.8837 "Beta-1,4-glucuronyltransferase 1 OS=Homo sapiens OX=9606 GN=B4GAT1 PE=1 SV=1" 4.21 2873.8 - 2.32E+06 - - - -0.2752 - 3.444 0.592 - 1025.4 1 2 0 -0.0004 16 0 0 0 8.31E+07 5.74E+07 - - - 6.4537 0.9999 221125_WJC_METTL3_EV_vs_WT_F03.15896.15896.2 2.63E-05 22-Dec K.LGSIAIQGAIEK[136.11].A "sp|P24752|THIL_HUMAN,tr|A0A5F9ZHL7|A0A5F9ZHL7_HUMAN,tr|A0A5F9ZHJ7|A0A5F9ZHJ7_HUMAN,tr|A0A5F9ZHH9|A0A5F9ZHH9_HUMAN,tr|A0A5F9ZHL1|A0A5F9ZHL1_HUMAN,tr|E9PRQ6|E9PRQ6_HUMAN,tr|H0YEL7|H0YEL7_HUMAN" 7 1206.7063 1.18 31334 15896 2 1206.705644 604.3604 "Acetyl-CoA acetyltransferase, mitochondrial OS=Homo sapiens OX=9606 GN=ACAT1 PE=1 SV=1" 6 2873.8 - 2.21E+06 - - - -0.5751 - 2.713 0.418 - 351.1 1 2 0 -0.0007 12 0 0 0 6.35E+07 5.40E+07 - - - 4.7542 0.9906 221125_WJC_METTL3_EV_vs_WT_F03.15898.15898.3 0.00895 Dec-44 K.LKEVFSIAGTVK.R "sp|Q9P2K5|MYEF2_HUMAN,tr|A0A0A0MR39|A0A0A0MR39_HUMAN,tr|A0A087WUT0|A0A087WUT0_HUMAN,tr|H0YN19|H0YN19_HUMAN,tr|A0A0A0MQW0|A0A0A0MQW0_HUMAN" 5 1290.7547 0.98 31336 15898 3 1290.756027 431.2589 Myelin expression factor 2 OS=Homo sapiens OX=9606 GN=MYEF2 PE=1 SV=3 8.59 2874 - 1.31E+06 - - - 0.9986 - 1.597 0.273 - 194.1 1 2 1 0.0013 12 0 0 0 4.58E+07 4.67E+07 - - - 2.8809 0.9983 221125_WJC_METTL3_EV_vs_WT_F03.15899.15899.3 0.00165 Dec-44 K.LK[136.11]EVFSIAGTVK[136.11].R "sp|Q9P2K5|MYEF2_HUMAN,tr|A0A0A0MR39|A0A0A0MR39_HUMAN,tr|A0A087WUT0|A0A087WUT0_HUMAN,tr|H0YN19|H0YN19_HUMAN,tr|A0A0A0MQW0|A0A0A0MQW0_HUMAN" 5 1306.7831 0.98 31337 15899 3 1306.78193 436.6017 Myelin expression factor 2 OS=Homo sapiens OX=9606 GN=MYEF2 PE=1 SV=3 8.59 2874.1 - 1.24E+06 - - - -0.9244 - 2.213 0.298 - 179.2 1 2 1 -0.0012 12 0 0 0 4.60E+07 4.67E+07 - - - 4.0639 0.9997 221125_WJC_METTL3_EV_vs_WT_F03.15900.15900.2 1.96E-05 24-Dec K.ELVYPPDYNPEGK.V "sp|P12956|XRCC6_HUMAN,tr|B1AHC9|B1AHC9_HUMAN" 2 1519.7195 1.35 31338 15900 2 1519.715953 760.867 X-ray repair cross-complementing protein 6 OS=Homo sapiens OX=9606 GN=XRCC6 PE=1 SV=2 4.14 2874.3 - 1.24E+06 - - - -2.3175 - 1.981 0.584 - 436.7 1 2 0 -0.0035 13 0 0 0 3.14E+07 2.32E+07 - - - 5.1078 1 221125_WJC_METTL3_EV_vs_WT_F03.15901.15901.2 4.02E-09 13/24 K.ELVYPPDYNPEGK[136.11].V "sp|P12956|XRCC6_HUMAN,tr|B1AHC9|B1AHC9_HUMAN" 2 1527.7337 1.35 31339 15901 2 1527.729966 764.8741 X-ray repair cross-complementing protein 6 OS=Homo sapiens OX=9606 GN=XRCC6 PE=1 SV=2 4.14 2874.4 - 1.23E+06 - - - -2.4278 - 2.262 0.633 - 420.2 1 2 0 -0.0037 13 0 0 0 3.14E+07 2.32E+07 - - - 5.8101 0.9999 221125_WJC_METTL3_EV_vs_WT_F03.15902.15902.2 0.000145 20-Dec K.EFSQSFDAAMK[136.11].G "sp|Q9Y5K5|UCHL5_HUMAN,tr|Q5LJA9|Q5LJA9_HUMAN,tr|H0Y6Y4|H0Y6Y4_HUMAN,tr|Q5LJB0|Q5LJB0_HUMAN,tr|Q5LJA5|Q5LJA5_HUMAN" 5 1267.5634 2.12 31340 15902 2 1267.562704 634.789 Ubiquitin carboxyl-terminal hydrolase isozyme L5 OS=Homo sapiens OX=9606 GN=UCHL5 PE=1 SV=3 4.37 2874.5 - 1.19E+06 - - - -0.5799 - 1.694 0.586 - 498 1 2 0 -0.0007 11 0 0 0 7.14E+07 3.36E+07 - - - 4.7949 0.9997 221125_WJC_METTL3_EV_vs_WT_F03.15904.15904.2 0.0314 20-Oct K.MQYFQPTIQEK.G "sp|Q8IZH2|XRN1_HUMAN,tr|H7C5E4|H7C5E4_HUMAN" 2 1411.6806 1.75 31342 15904 2 1411.679261 706.8476 5'-3' exoribonuclease 1 OS=Homo sapiens OX=9606 GN=XRN1 PE=1 SV=1 5.75 2874.7 - 851627 - - - -0.9393 - 2.022 0.402 - 325.4 1 2 0 -0.0013 11 0 0 0 2.15E+07 1.23E+07 - - - 3.9145 0.9995 221125_WJC_METTL3_EV_vs_WT_F03.15908.15908.2 0.000291 18-Nov R.SAPLEIGLQR[166.11].S "sp|Q6P1J9|CDC73_HUMAN,tr|A0A2R8Y640|A0A2R8Y640_HUMAN,tr|A0A2R8YHB3|A0A2R8YHB3_HUMAN,tr|A0A1B0GUB2|A0A1B0GUB2_HUMAN,tr|A0A3B3IRP5|A0A3B3IRP5_HUMAN" 5 1092.6167 1.27 31344 15908 2 1092.615147 547.3156 Parafibromin OS=Homo sapiens OX=9606 GN=CDC73 PE=1 SV=1 5.72 2875.4 - 1.86E+06 - - - -1.4012 - 1.841 0.371 - 469.9 1 2 0 -0.0015 10 0 0 0 5.77E+07 4.54E+07 - - - 3.4843 0.9998 221125_WJC_METTL3_EV_vs_WT_F03.15911.15911.2 0.000188 18-Dec R.SAPLEIGLQR.S "sp|Q6P1J9|CDC73_HUMAN,tr|A0A2R8Y640|A0A2R8Y640_HUMAN,tr|A0A2R8YHB3|A0A2R8YHB3_HUMAN,tr|A0A1B0GUB2|A0A1B0GUB2_HUMAN,tr|A0A3B3IRP5|A0A3B3IRP5_HUMAN" 5 1082.6084 1.27 31347 15911 2 1082.608495 542.3115 Parafibromin OS=Homo sapiens OX=9606 GN=CDC73 PE=1 SV=1 5.72 2875.6 - 1.41E+06 - - - 0.0804 - 1.866 0.432 - 546.9 1 2 0 0.0001 10 0 0 0 5.75E+07 4.54E+07 - - - 3.9729 1 221125_WJC_METTL3_EV_vs_WT_F03.15915.15915.3 2.09E-07 14/52 K.LFC[160.03]TSC[160.03]NVVLNHVR[166.11].K "sp|Q9UFW8|CGBP1_HUMAN,tr|C9JUJ0|C9JUJ0_HUMAN" 2 1727.8475 0.71 31351 15915 3 1727.844992 576.9564 CGG triplet repeat-binding protein 1 OS=Homo sapiens OX=9606 GN=CGGBP1 PE=1 SV=2 8.08 2876.1 - 1.31E+06 - - - -1.4515 - 2.536 0.524 - 198.9 1 2 0 -0.0025 14 0 0 0 8.73E+06 1.24E+07 - - - 6.8545 1 221125_WJC_METTL3_EV_vs_WT_F03.15916.15916.2 0.000568 16/28 K.DLVTEDGADPNPYVK.T sp|O00443|P3C2A_HUMAN 1 1631.7679 1.78 31352 15916 2 1631.768655 816.8912 Phosphatidylinositol 4-phosphate 3-kinase C2 domain-containing subunit alpha OS=Homo sapiens OX=9606 GN=PIK3C2A PE=1 SV=2 3.84 2876.2 - 830384 - - - 0.4737 - 2.794 0.605 - 761 1 2 0 0.0008 15 0 0 0 1.77E+07 9.95E+06 - - - 6.0354 0.9999 221125_WJC_METTL3_EV_vs_WT_F03.15917.15917.2 1.25E-06 14/28 K.DLVTEDGADPNPYVK[136.11].T sp|O00443|P3C2A_HUMAN 1 1639.7821 1.78 31353 15917 2 1639.782491 820.8983 Phosphatidylinositol 4-phosphate 3-kinase C2 domain-containing subunit alpha OS=Homo sapiens OX=9606 GN=PIK3C2A PE=1 SV=2 3.84 2876.3 - 787032 - - - 0.2494 - 2.477 0.542 - 541.5 1 2 0 0.0004 15 0 0 0 1.77E+07 9.95E+06 - - - 5.2741 0.9917 221125_WJC_METTL3_EV_vs_WT_F03.15920.15920.2 0.0117 20-Oct K.IDNSNTPFLPK[136.11].L sp|Q01780|EXOSX_HUMAN 1 1252.6543 1.85 31356 15920 2 1252.649908 627.3344 Exosome component 10 OS=Homo sapiens OX=9606 GN=EXOSC10 PE=1 SV=2 5.84 2876.7 - 516007 - - - -3.5078 - 1.683 0.231 - 246.2 1 2 0 -0.0044 11 0 0 0 2.94E+07 1.59E+07 - - - 2.1541 1 221125_WJC_METTL3_EV_vs_WT_F03.15924.15924.2 5.37E-05 16/30 R.TALASGGVLDASGDYR[166.11].V sp|O43505|B4GA1_HUMAN 1 1561.7612 1.45 31358 15924 2 1561.759257 781.8879 "Beta-1,4-glucuronyltransferase 1 OS=Homo sapiens OX=9606 GN=B4GAT1 PE=1 SV=1" 4.21 2877.2 - 3.82E+06 - - - -1.2249 - 3.307 0.568 - 783 1 2 0 -0.0019 16 0 0 0 8.31E+07 5.74E+07 - - - 6.1762 0.9986 221125_WJC_METTL3_EV_vs_WT_F03.15926.15926.3 0.0773 Dec-40 R.FVNVVPTFGK[136.11]K[136.11].K "sp|P62861|RS30_HUMAN,tr|E9PR30|E9PR30_HUMAN" 2 1250.7358 0.53 31360 15926 3 1250.735521 417.9192 40S ribosomal protein S30 OS=Homo sapiens OX=9606 GN=FAU PE=1 SV=1 10 2877.4 - 1.67E+06 - - - -0.2183 - 1.672 0.274 - 173.5 1 2 0 -0.0003 11 0 0 0 1.28E+07 2.43E+07 - - - 3.055 0.9999 221125_WJC_METTL3_EV_vs_WT_F03.15927.15927.3 3.39E-05 Dec-52 R.LVVPASQC[160.03]GSLIGK.G "sp|P57721|PCBP3_HUMAN,sp|Q15366|PCBP2_HUMAN,tr|F8W1G6|F8W1G6_HUMAN,tr|E9PFP8|E9PFP8_HUMAN,tr|J3QT27|J3QT27_HUMAN,tr|F8VZX2|F8VZX2_HUMAN,tr|F8W0G4|F8W0G4_HUMAN,tr|F8VXH9|F8VXH9_HUMAN,tr|H3BRU6|H3BRU6_HUMAN,tr|H3BND9|H3BND9_HUMAN" 10 1427.7806 1.14 31361 15927 3 1427.782443 476.9342 Poly(rC)-binding protein 3 OS=Homo sapiens OX=9606 GN=PCBP3 PE=1 SV=2 8.22 2877.5 - 1.30E+06 - - - 1.2656 - 2.2 0.41 - 165.7 1 2 0 0.0018 14 0 0 0 1.26E+07 1.10E+07 - - - 5.2059 0.9999 221125_WJC_METTL3_EV_vs_WT_F03.15928.15928.2 2.13E-05 20-Dec K.MQYFQPTIQEK[136.11].G "sp|Q8IZH2|XRN1_HUMAN,tr|H7C5E4|H7C5E4_HUMAN" 2 1419.6948 1.75 31362 15928 2 1419.693802 710.8547 5'-3' exoribonuclease 1 OS=Homo sapiens OX=9606 GN=XRN1 PE=1 SV=1 5.75 2877.6 - 1.28E+06 - - - -0.6938 - 2.154 0.521 - 514.8 1 2 0 -0.001 11 0 0 0 2.15E+07 1.23E+07 - - - 4.9646 1 221125_WJC_METTL3_EV_vs_WT_F03.15929.15929.2 7.88E-08 15/26 K.NAIANASTLAEVER.L "sp|P09661|RU2A_HUMAN,tr|H0YMA0|H0YMA0_HUMAN,tr|H0YLR3|H0YLR3_HUMAN" 3 1457.7474 1.38 31363 15929 2 1457.751594 729.881 U2 small nuclear ribonucleoprotein A' OS=Homo sapiens OX=9606 GN=SNRPA1 PE=1 SV=2 4.53 2877.8 - 1.13E+06 - - - 2.8626 - 3.067 0.565 - 834.5 1 2 0 0.0042 14 0 0 0 7.49E+07 5.44E+07 - - - 6.0251 0.9998 221125_WJC_METTL3_EV_vs_WT_F03.15930.15930.3 0.000206 Dec-44 K.LVTDQNISENWR.V "sp|P24666|PPAC_HUMAN,tr|F2Z2Q9|F2Z2Q9_HUMAN,tr|G5E9R5|G5E9R5_HUMAN" 3 1473.7212 1 31364 15930 3 1473.724088 492.2477 Low molecular weight phosphotyrosine protein phosphatase OS=Homo sapiens OX=9606 GN=ACP1 PE=1 SV=3 4.37 2877.9 - 1.03E+06 - - - 1.9556 - 2.311 0.406 - 215.3 1 2 0 0.0029 12 0 0 0 8.77E+06 8.80E+06 - - - 5.3876 0.9118 221125_WJC_METTL3_EV_vs_WT_F03.15932.15932.2 0.00527 22-Dec K.LK[136.11]EVFSIAGTVK[136.11].R "sp|Q9P2K5|MYEF2_HUMAN,tr|A0A0A0MR39|A0A0A0MR39_HUMAN,tr|A0A087WUT0|A0A087WUT0_HUMAN,tr|H0YN19|H0YN19_HUMAN,tr|A0A0A0MQW0|A0A0A0MQW0_HUMAN" 5 1306.7831 1.24 31366 15932 2 1306.77616 654.3988 Myelin expression factor 2 OS=Homo sapiens OX=9606 GN=MYEF2 PE=1 SV=3 8.59 2878.2 - 641980 - - - -5.3398 - 1.901 0.361 - 161.1 1 2 1 -0.007 12 0 0 0 9.44E+06 7.61E+06 - - - 3.3954 0.9999 221125_WJC_METTL3_EV_vs_WT_F03.15933.15933.2 0.000539 16/26 K.AINQQTGAFVEISR[166.11].Q "sp|Q92945|FUBP2_HUMAN,tr|M0R3J3|M0R3J3_HUMAN,tr|M0R0C6|M0R0C6_HUMAN,tr|A0A087WTP3|A0A087WTP3_HUMAN" 4 1542.803 1.11 31367 15933 2 1542.801979 772.4088 Far upstream element-binding protein 2 OS=Homo sapiens OX=9606 GN=KHSRP PE=1 SV=4 6.05 2878.3 - 639734 - - - -0.6462 - 2.893 0.407 - 1024.2 1 2 0 -0.001 14 0 0 0 2.51E+07 2.26E+07 - - - 4.7126 0.9981 221125_WJC_METTL3_EV_vs_WT_F03.15935.15935.3 5.06E-05 15/40 K.FAAQELIEVK[136.11]R[166.11].G "sp|Q86U44|MTA70_HUMAN,tr|F5H6D8|F5H6D8_HUMAN,tr|H0YFV6|H0YFV6_HUMAN,tr|B4DTN4|B4DTN4_HUMAN" 4 1320.7521 0.01 31368 15935 3 1320.751079 441.258 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 6.14 2878.5 - 1.00E+07 - - - -0.7397 - 2.523 0.152 - 210.2 1 2 0 -0.001 11 0 0 0 6.28E+06 4.69E+08 - - - 2.8634 1 221125_WJC_METTL3_EV_vs_WT_F03.15937.15937.3 1.36E-08 17/48 K.YFTC[160.03]DEGHGIFVR[166.11].Q "sp|Q14203|DCTN1_HUMAN,tr|C9JTE5|C9JTE5_HUMAN,tr|A0A804CDA6|A0A804CDA6_HUMAN,tr|C9JJN7|C9JJN7_HUMAN,tr|E7EX90|E7EX90_HUMAN,tr|C9JJD0|C9JJD0_HUMAN,tr|A0A7P0Z4C3|A0A7P0Z4C3_HUMAN,tr|Q6AWB1|Q6AWB1_HUMAN,tr|C9JZA4|C9JZA4_HUMAN,tr|E9PCY0|E9PCY0_HUMAN,tr|C9JKG6|C9JKG6_HUMAN" 11 1609.7223 1.72 31369 15937 3 1609.721145 537.5814 Dynactin subunit 1 OS=Homo sapiens OX=9606 GN=DCTN1 PE=1 SV=3 5.32 2878.7 - 2.95E+06 - - - -0.707 - 3.305 0.657 - 285.6 1 2 0 -0.0011 13 0 0 0 8.35E+07 4.86E+07 - - - 9.1058 0.9991 221125_WJC_METTL3_EV_vs_WT_F03.15938.15938.3 0.00223 13/48 R.TPHVLVLGSGVYR[166.11].L "sp|P27708|PYR1_HUMAN,tr|F8VPD4|F8VPD4_HUMAN" 2 1406.791 0.68 31370 15938 3 1406.790218 469.9376 CAD protein OS=Homo sapiens OX=9606 GN=CAD PE=1 SV=3 8.44 2878.9 - 347638 - - - -0.5232 - 1.962 0.268 - 197.7 1 2 0 -0.0007 13 0 0 0 8.66E+06 1.26E+07 - - - 3.355 0.9893 221125_WJC_METTL3_EV_vs_WT_F03.15939.15939.3 1.2 Oct-36 K.LPKPVQDLIK.M sp|P09874|PARP1_HUMAN 1 1149.7121 1.13 31371 15939 3 1149.710342 384.2447 Poly [ADP-ribose] polymerase 1 OS=Homo sapiens OX=9606 GN=PARP1 PE=1 SV=4 8.59 2879 - 893007 - - - -1.5682 - 1.516 0.197 - 70.5 1 2 0 -0.0018 10 0 0 0 1.19E+07 1.05E+07 - - - 1.951 0.9996 221125_WJC_METTL3_EV_vs_WT_F03.15940.15940.2 1.77E-06 20-Nov K.IDNSNTPFLPK.L sp|Q01780|EXOSX_HUMAN 1 1244.6401 1.45 31372 15940 2 1244.642986 623.3273 Exosome component 10 OS=Homo sapiens OX=9606 GN=EXOSC10 PE=1 SV=2 5.84 2879.1 - 861919 - - - 2.3171 - 2.388 0.433 - 322.6 1 2 0 0.0029 11 0 0 0 6.85E+06 4.72E+06 - - - 4.593 0.9999 221125_WJC_METTL3_EV_vs_WT_F03.15941.15941.3 6.18E-05 Nov-52 R.LVVPASQC[160.03]GSLIGK[136.11].G "sp|P57721|PCBP3_HUMAN,sp|Q15366|PCBP2_HUMAN,tr|F8W1G6|F8W1G6_HUMAN,tr|E9PFP8|E9PFP8_HUMAN,tr|J3QT27|J3QT27_HUMAN,tr|F8VZX2|F8VZX2_HUMAN,tr|F8W0G4|F8W0G4_HUMAN,tr|F8VXH9|F8VXH9_HUMAN,tr|H3BRU6|H3BRU6_HUMAN,tr|H3BND9|H3BND9_HUMAN" 10 1435.7948 1.13 31373 15941 3 1435.797943 479.6056 Poly(rC)-binding protein 3 OS=Homo sapiens OX=9606 GN=PCBP3 PE=1 SV=2 8.22 2879.2 - 832059 - - - 2.164 - 2.446 0.438 - 175.3 1 2 0 0.0031 14 0 0 0 1.24E+07 1.10E+07 - - - 5.7994 0.9996 221125_WJC_METTL3_EV_vs_WT_F03.15943.15943.2 0.218 13/18 K.RLLLQLEATK.N "sp|Q13561|DCTN2_HUMAN,tr|H0YI98|H0YI98_HUMAN,tr|A8K8J9|A8K8J9_HUMAN,tr|F8W1I6|F8W1I6_HUMAN,tr|A0A7I2V4H4|A0A7I2V4H4_HUMAN,tr|A0A7I2V390|A0A7I2V390_HUMAN,tr|A0A7I2V4Y9|A0A7I2V4Y9_HUMAN,tr|F8VW18|F8VW18_HUMAN" 8 1183.7289 5.8 31375 15943 2 1183.729774 592.8717 Dynactin subunit 2 OS=Homo sapiens OX=9606 GN=DCTN2 PE=1 SV=4 8.75 2879.5 - 747693 - - - 0.7738 - 2.18 0.302 - 580.1 1 2 0 0.0009 10 0 0 0 1.15E+07 1.99E+06 - - - 3.4466 0.9998 221125_WJC_METTL3_EV_vs_WT_F03.15945.15945.2 0.000378 20-Sep K.ASWSSLSMDEK.V "sp|P13073|COX41_HUMAN,tr|Q86WV2|Q86WV2_HUMAN,tr|H3BN72|H3BN72_HUMAN,tr|H3BPG0|H3BPG0_HUMAN,tr|H3BNV9|H3BNV9_HUMAN" 5 1239.5442 1.24 31377 15945 2 1239.545847 620.7794 "Cytochrome c oxidase subunit 4 isoform 1, mitochondrial OS=Homo sapiens OX=9606 GN=COX4I1 PE=1 SV=1" 4.37 2879.8 - 687974 - - - 1.3666 - 2.175 0.563 - 212.5 1 2 0 0.0017 11 0 0 0 4.40E+07 3.54E+07 - - - 5.3008 1 221125_WJC_METTL3_EV_vs_WT_F03.15946.15946.3 2.39E-06 15/52 K.AINQQTGAFVEISR.Q "sp|Q92945|FUBP2_HUMAN,tr|M0R3J3|M0R3J3_HUMAN,tr|M0R0C6|M0R0C6_HUMAN,tr|A0A087WTP3|A0A087WTP3_HUMAN" 4 1532.7947 0.2 31378 15946 3 1532.796564 511.9388 Far upstream element-binding protein 2 OS=Homo sapiens OX=9606 GN=KHSRP PE=1 SV=4 6.05 2879.9 - 615484 - - - 1.2122 - 2.655 0.508 - 241.5 1 2 0 0.0019 14 0 0 0 8.63E+06 4.22E+07 - - - 6.7981 0.9974 221125_WJC_METTL3_EV_vs_WT_F03.15948.15948.2 0.00155 14-Jul K.EC[160.03]ADLWPR.L "sp|P62829|RL23_HUMAN,tr|J3KTJ3|J3KTJ3_HUMAN" 2 1045.4651 1.03 31379 15948 2 1045.465279 523.7398 60S ribosomal protein L23 OS=Homo sapiens OX=9606 GN=RPL23 PE=1 SV=1 4.37 2880.1 - 5.90E+06 - - - 0.1569 - 1.695 0.131 - 281.1 1 2 0 0.0002 8 0 0 0 6.34E+07 6.18E+07 - - - 1.6 1 221125_WJC_METTL3_EV_vs_WT_F03.15951.15951.3 0.000276 16/48 K.YFTC[160.03]DEGHGIFVR.Q "sp|Q14203|DCTN1_HUMAN,tr|C9JTE5|C9JTE5_HUMAN,tr|A0A804CDA6|A0A804CDA6_HUMAN,tr|C9JJN7|C9JJN7_HUMAN,tr|E7EX90|E7EX90_HUMAN,tr|C9JJD0|C9JJD0_HUMAN,tr|A0A7P0Z4C3|A0A7P0Z4C3_HUMAN,tr|Q6AWB1|Q6AWB1_HUMAN,tr|C9JZA4|C9JZA4_HUMAN,tr|E9PCY0|E9PCY0_HUMAN,tr|C9JKG6|C9JKG6_HUMAN" 11 1599.714 1.71 31381 15951 3 1599.713172 534.2453 Dynactin subunit 1 OS=Homo sapiens OX=9606 GN=DCTN1 PE=1 SV=3 5.32 2880.4 - 6.87E+06 - - - -0.5257 - 2.853 0.625 - 266.5 1 2 0 -0.0008 13 0 0 0 8.35E+07 4.87E+07 - - - 8.3503 0.9999 221125_WJC_METTL3_EV_vs_WT_F03.15953.15953.2 0.000236 14/26 K.NAIANASTLAEVER[166.11].L "sp|P09661|RU2A_HUMAN,tr|H0YMA0|H0YMA0_HUMAN,tr|H0YLR3|H0YLR3_HUMAN" 3 1467.7557 1.39 31383 15953 2 1467.756591 734.8851 U2 small nuclear ribonucleoprotein A' OS=Homo sapiens OX=9606 GN=SNRPA1 PE=1 SV=2 4.53 2880.5 - 2.64E+06 - - - 0.6132 - 2.884 0.528 - 654.3 1 2 0 0.0009 14 0 0 0 7.49E+07 5.40E+07 - - - 5.5985 0.999 221125_WJC_METTL3_EV_vs_WT_F03.15954.15954.2 1.18 16-Oct R.R[166.11]DVDFELIK[136.11].V "sp|P48643|TCPE_HUMAN,tr|E9PCA1|E9PCA1_HUMAN,tr|B7ZAR1|B7ZAR1_HUMAN,tr|E7ENZ3|E7ENZ3_HUMAN" 4 1151.6305 0.31 31384 15954 2 1151.630795 576.8225 T-complex protein 1 subunit epsilon OS=Homo sapiens OX=9606 GN=CCT5 PE=1 SV=1 4.56 2880.5 - 2.59E+06 - - - 0.218 - 2.128 0.152 - 319 1 2 0 0.0003 9 0 0 0 1.87E+07 6.02E+07 - - - 2.3484 0.9999 221125_WJC_METTL3_EV_vs_WT_F03.15956.15956.2 3.88E-05 20-Oct K.ASWSSLSMDEK[136.11].V "sp|P13073|COX41_HUMAN,tr|Q86WV2|Q86WV2_HUMAN,tr|H3BN72|H3BN72_HUMAN,tr|H3BPG0|H3BPG0_HUMAN,tr|H3BNV9|H3BNV9_HUMAN" 5 1247.5584 1.24 31386 15956 2 1247.55835 624.7865 "Cytochrome c oxidase subunit 4 isoform 1, mitochondrial OS=Homo sapiens OX=9606 GN=COX4I1 PE=1 SV=1" 4.37 2880.7 - 1.44E+06 - - - -0.0024 - 2.021 0.559 - 277.5 1 2 0 0 11 0 0 0 4.40E+07 3.54E+07 - - - 5.0732 0.9998 221125_WJC_METTL3_EV_vs_WT_F03.15957.15957.2 0.00258 16-Oct K.FEEMIQQIK.E "sp|P48643|TCPE_HUMAN,tr|E9PCA1|E9PCA1_HUMAN,tr|B7ZAR1|B7ZAR1_HUMAN,tr|E7ENZ3|E7ENZ3_HUMAN" 4 1164.5849 0.64 31387 15957 2 1164.583779 583.2997 T-complex protein 1 subunit epsilon OS=Homo sapiens OX=9606 GN=CCT5 PE=1 SV=1 4.53 2880.8 - 1.36E+06 - - - -0.9591 - 2.019 0.436 - 290.1 1 2 0 -0.0011 9 0 0 0 3.28E+07 5.10E+07 - - - 4.2936 0.9999 221125_WJC_METTL3_EV_vs_WT_F03.15958.15958.3 0.000169 Nov-32 R.R[166.11]DVDFELIK[136.11].V "sp|P48643|TCPE_HUMAN,tr|E9PCA1|E9PCA1_HUMAN,tr|B7ZAR1|B7ZAR1_HUMAN,tr|E7ENZ3|E7ENZ3_HUMAN" 4 1151.6305 0.001 31388 15958 3 1151.629044 384.8841 T-complex protein 1 subunit epsilon OS=Homo sapiens OX=9606 GN=CCT5 PE=1 SV=1 4.56 2880.9 - 1.35E+06 - - - -1.3025 - 2.064 0.474 - 234.8 1 2 0 -0.0015 9 0 0 0 0.00E+00 2.26E+07 - - - 6.0081 1 221125_WJC_METTL3_EV_vs_WT_F03.15959.15959.2 1.51E-08 16/26 K.FAGSAGWEGTESLK[136.11].K "sp|Q13123|RED_HUMAN,tr|A0A0C4DGW5|A0A0C4DGW5_HUMAN" 2 1446.6871 1.08 31389 15959 2 1446.689105 724.3508 Protein Red OS=Homo sapiens OX=9606 GN=IK PE=1 SV=3 4.53 2881 - 1.19E+06 - - - 1.4143 - 2.675 0.636 - 507.1 1 2 0 0.002 14 0 0 0 1.63E+07 1.51E+07 - - - 6.207 0.9998 221125_WJC_METTL3_EV_vs_WT_F03.15960.15960.2 1.80E-05 18-Oct R.QYQIDAAIVR[166.11].L "sp|Q13619|CUL4A_HUMAN,sp|Q13620|CUL4B_HUMAN,tr|A0A7P0T8P8|A0A7P0T8P8_HUMAN,tr|A0A669KAX4|A0A669KAX4_HUMAN,tr|A0A0A0MR50|A0A0A0MR50_HUMAN,tr|K4DI93|K4DI93_HUMAN,tr|A0A7P0T9C8|A0A7P0T9C8_HUMAN,tr|A0A7P0T954|A0A7P0T954_HUMAN,tr|A0A7P0T9L3|A0A7P0T9L3_HUMAN,tr|A0A7P0TAQ3|A0A7P0TAQ3_HUMAN" 10 1185.6381 0.23 31390 15960 2 1185.637897 593.8263 Cullin-4A OS=Homo sapiens OX=9606 GN=CUL4A PE=1 SV=3 5.84 2881.1 - 1.17E+06 - - - -0.2066 - 1.918 0.437 - 424.9 1 2 0 -0.0002 10 0 0 0 3.66E+06 1.61E+07 - - - 4.0865 0.9835 221125_WJC_METTL3_EV_vs_WT_F03.15961.15961.2 2.32E-05 24-Oct S.AVPELATDPELEK[136.11].K "sp|Q86U44|MTA70_HUMAN,tr|B4E349|B4E349_HUMAN,tr|F5H6D8|F5H6D8_HUMAN,tr|H0YFV6|H0YFV6_HUMAN,tr|B4DTN4|B4DTN4_HUMAN" 5 1418.7384 0.01 31391 15961 2 1418.740281 710.3765 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 4 2881.2 - 1.17E+06 - - - 1.3075 - 1.984 0.463 - 258.1 1 1 0 0.0019 13 0 0 0 1.47E+06 2.40E+08 - - - 4.2185 0.9987 221125_WJC_METTL3_EV_vs_WT_F03.15962.15962.2 0.00959 16-Jun R.GTYDILVTK.D "sp|P13861|KAP2_HUMAN,tr|H7C1L0|H7C1L0_HUMAN" 2 1008.5492 0.88 31392 15962 2 1008.548011 505.2819 cAMP-dependent protein kinase type II-alpha regulatory subunit OS=Homo sapiens OX=9606 GN=PRKAR2A PE=1 SV=2 5.83 2881.3 - 737724 - - - -1.1412 - 1.23 0.363 - 102.2 1 2 0 -0.0012 9 0 0 0 1.38E+07 1.56E+07 - - - 2.3207 0.9999 221125_WJC_METTL3_EV_vs_WT_F03.15965.15965.3 0.00157 16/40 K.LTFVGELAHGR.F "sp|Q9UKM7|MA1B1_HUMAN,tr|H0YG20|H0YG20_HUMAN,tr|A0A804HKS1|A0A804HKS1_HUMAN,tr|H0YGV7|H0YGV7_HUMAN,tr|A0A804HL65|A0A804HL65_HUMAN,tr|A0A804HK01|A0A804HK01_HUMAN,tr|A0A804HJ23|A0A804HJ23_HUMAN,tr|A0A804HHU1|A0A804HHU1_HUMAN,tr|A0A804HK86|A0A804HK86_HUMAN,tr|A0A804HL61|A0A804HL61_HUMAN,tr|A0A804HJ66|A0A804HJ66_HUMAN,tr|H0YGQ1|H0YGQ1_HUMAN,tr|H0YI64|H0YI64_HUMAN" 13 1198.6459 1.45 31395 15965 3 1198.643888 400.5559 "Endoplasmic reticulum mannosyl-oligosaccharide 1,2-alpha-mannosidase OS=Homo sapiens OX=9606 GN=MAN1B1 PE=1 SV=2" 6.75 2881.7 - 633570 - - - -1.6419 - 2.733 0.424 - 320.5 1 2 0 -0.002 11 0 0 0 1.64E+07 1.13E+07 - - - 6.1228 0.9999 221125_WJC_METTL3_EV_vs_WT_F03.15966.15966.3 0.00147 Sep-36 K.RLLLQLEATK.N "sp|Q13561|DCTN2_HUMAN,tr|H0YI98|H0YI98_HUMAN,tr|A8K8J9|A8K8J9_HUMAN,tr|F8W1I6|F8W1I6_HUMAN,tr|A0A7I2V4H4|A0A7I2V4H4_HUMAN,tr|A0A7I2V390|A0A7I2V390_HUMAN,tr|A0A7I2V4Y9|A0A7I2V4Y9_HUMAN,tr|F8VW18|F8VW18_HUMAN" 8 1183.7289 2.41 31396 15966 3 1183.727535 395.5836 Dynactin subunit 2 OS=Homo sapiens OX=9606 GN=DCTN2 PE=1 SV=4 8.75 2881.8 - 327405 - - - -1.1177 - 2.022 0.415 - 108.7 1 2 0 -0.0013 10 0 0 0 4.86E+06 2.02E+06 - - - 5.2227 0.9997 221125_WJC_METTL3_EV_vs_WT_F03.15971.15971.2 0.00109 18-Oct K.NLQSAEEWYK[136.11].S sp|Q16352|AINX_HUMAN 1 1274.6023 1.9 31399 15971 2 1274.600991 638.3084 Alpha-internexin OS=Homo sapiens OX=9606 GN=INA PE=1 SV=2 4.53 2882.4 - 1.41E+06 - - - -1.0011 - 1.959 0.403 - 313 1 2 0 -0.0013 10 0 0 0 3.17E+07 1.67E+07 - - - 3.8941 0.9797 221125_WJC_METTL3_EV_vs_WT_F03.15972.15972.3 0.0689 Nov-36 F.VLVLYDEIK[136.11]K[136.11].Y "sp|P12235|ADT1_HUMAN,sp|P05141|ADT2_HUMAN,sp|P12236|ADT3_HUMAN" 3 1234.7508 0.87 31400 15972 3 1234.750162 412.5909 ADP\ATP translocase 1 OS=Homo sapiens OX=9606 GN=SLC25A4 PE=1 SV=4 6.04 2882.5 - 1.35E+06 - - - -0.4973 - 1.764 0.393 - 157.6 1 1 0 -0.0006 10 0 0 0 1.18E+07 1.36E+07 - - - 4.579 0.9998 221125_WJC_METTL3_EV_vs_WT_F03.15974.15974.3 4.49E-05 17/44 K.NLYSDDIPHALR[166.11].E "sp|P60228|EIF3E_HUMAN,tr|A0A7I2V3I2|A0A7I2V3I2_HUMAN,tr|A0A7I2V570|A0A7I2V570_HUMAN,tr|A0A7I2V2Q9|A0A7I2V2Q9_HUMAN,tr|H0YBP5|H0YBP5_HUMAN,tr|A0A7I2V2H9|A0A7I2V2H9_HUMAN,tr|B3KW56|B3KW56_HUMAN,tr|A0A7I2V4B4|A0A7I2V4B4_HUMAN,tr|A0A7I2V3I0|A0A7I2V3I0_HUMAN,tr|A0A7I2V3S3|A0A7I2V3S3_HUMAN,tr|A0A7I2V4G3|A0A7I2V4G3_HUMAN,tr|A0A7I2V3W9|A0A7I2V3W9_HUMAN,tr|H0YBR5|H0YBR5_HUMAN,tr|A0A7I2V429|A0A7I2V429_HUMAN,tr|A0A7I2V2W0|A0A7I2V2W0_HUMAN,tr|A0A161SXE1|A0A161SXE1_HUMAN" 16 1422.7131 1.06 31402 15974 3 1422.709295 475.245 Eukaryotic translation initiation factor 3 subunit E OS=Homo sapiens OX=9606 GN=EIF3E PE=1 SV=1 5.21 2882.7 - 1.04E+06 - - - -2.6731 - 2.283 0.426 - 379.1 1 2 0 -0.0038 12 0 0 0 1.64E+08 1.56E+08 - - - 5.5766 0.9995 221125_WJC_METTL3_EV_vs_WT_F03.15975.15975.2 0.000483 18-Jun R.DSHEPTYGIY.- sp|Q96DV4|RM38_HUMAN 1 1180.5037 - 31403 15975 2 1180.501835 591.2591 "39S ribosomal protein L38, mitochondrial OS=Homo sapiens OX=9606 GN=MRPL38 PE=1 SV=2" 4.35 2882.8 - 1.03E+06 - - - -1.5527 - 1.333 0.515 - 87.3 1 2 0 -0.0018 10 0 0 0 - - - - - 3.6465 0.9857 221125_WJC_METTL3_EV_vs_WT_F03.15976.15976.2 0.000148 14-Nov L.PLVQVDEK[136.11].G sp|Q92615|LAR4B_HUMAN 1 934.5215 1.61 31404 15976 2 934.519532 468.268 La-related protein 4B OS=Homo sapiens OX=9606 GN=LARP4B PE=1 SV=3 4.37 2882.9 - 906890 - - - -2.1027 - 2.401 0.469 - 395.1 1 1 0 -0.002 8 0 0 0 1.23E+07 7.64E+06 - - - 5.146 0.9999 221125_WJC_METTL3_EV_vs_WT_F03.15978.15978.3 0.000304 14/40 K.LTFVGELAHGR[166.11].F "sp|Q9UKM7|MA1B1_HUMAN,tr|H0YG20|H0YG20_HUMAN,tr|A0A804HKS1|A0A804HKS1_HUMAN,tr|H0YGV7|H0YGV7_HUMAN,tr|A0A804HL65|A0A804HL65_HUMAN,tr|A0A804HK01|A0A804HK01_HUMAN,tr|A0A804HJ23|A0A804HJ23_HUMAN,tr|A0A804HHU1|A0A804HHU1_HUMAN,tr|A0A804HK86|A0A804HK86_HUMAN,tr|A0A804HL61|A0A804HL61_HUMAN,tr|A0A804HJ66|A0A804HJ66_HUMAN,tr|H0YGQ1|H0YGQ1_HUMAN,tr|H0YI64|H0YI64_HUMAN" 13 1208.6541 1.41 31406 15978 3 1208.654047 403.892 "Endoplasmic reticulum mannosyl-oligosaccharide 1,2-alpha-mannosidase OS=Homo sapiens OX=9606 GN=MAN1B1 PE=1 SV=2" 6.75 2883.1 - 807406 - - - -0.0654 - 2.303 0.37 - 267.6 1 2 0 -0.0001 11 0 0 0 1.64E+07 1.16E+07 - - - 5.035 0.9996 221125_WJC_METTL3_EV_vs_WT_F03.15979.15979.2 0.000625 24-Nov R.IQPGNPNYTLSLK[136.11].C "sp|P63010|AP2B1_HUMAN,tr|A0A087X253|A0A087X253_HUMAN" 2 1451.7864 2.41 31407 15979 2 1451.783995 726.9005 AP-2 complex subunit beta OS=Homo sapiens OX=9606 GN=AP2B1 PE=1 SV=1 8.59 2883.3 - 776652 - - - -1.6421 - 2.075 0.389 - 335.9 1 2 0 -0.0024 13 0 0 0 3.26E+07 1.35E+07 - - - 3.7869 0.9999 221125_WJC_METTL3_EV_vs_WT_F03.15985.15985.2 2.59E-05 20-Sep K.EFSQSFDAAMK.G "sp|Q9Y5K5|UCHL5_HUMAN,tr|Q5LJA9|Q5LJA9_HUMAN,tr|H0Y6Y4|H0Y6Y4_HUMAN,tr|Q5LJB0|Q5LJB0_HUMAN,tr|Q5LJA5|Q5LJA5_HUMAN" 5 1259.5492 2.15 31412 15985 2 1259.549702 630.7819 Ubiquitin carboxyl-terminal hydrolase isozyme L5 OS=Homo sapiens OX=9606 GN=UCHL5 PE=1 SV=3 4.37 2884 - 1.23E+06 - - - 0.3676 - 1.925 0.545 - 275.3 1 2 0 0.0005 11 0 0 0 7.23E+07 3.36E+07 - - - 4.838 0.9998 221125_WJC_METTL3_EV_vs_WT_F03.15990.15990.2 0.000102 13/24 K.VEEAEPEEFVVEK[136.11].V "sp|Q13185|CBX3_HUMAN,tr|C9JMM0|C9JMM0_HUMAN,tr|S4R2Y4|S4R2Y4_HUMAN,tr|B8ZZ43|B8ZZ43_HUMAN" 4 1540.7388 1.55 31416 15990 2 1540.736221 771.3767 Chromobox protein homolog 3 OS=Homo sapiens OX=9606 GN=CBX3 PE=1 SV=4 3.9 2884.4 - 2.79E+06 - - - -1.6869 - 2.685 0.504 - 545.5 1 2 0 -0.0026 13 0 0 0 9.87E+07 6.37E+07 - - - 5.2976 0.9999 221125_WJC_METTL3_EV_vs_WT_F03.15992.15992.2 6.72E-06 13/24 K.STSQVAASLLASK.S sp|Q9NXV6|CARF_HUMAN 1 1261.6878 0.88 31418 15992 2 1261.68757 631.8512 CDKN2A-interacting protein OS=Homo sapiens OX=9606 GN=CDKN2AIP PE=1 SV=3 8.47 2884.5 - 1.01E+06 - - - -0.1672 - 2.541 0.507 - 591.8 1 2 0 -0.0002 13 0 0 0 9.24E+06 1.06E+07 - - - 5.1791 0.9999 221125_WJC_METTL3_EV_vs_WT_F03.15993.15993.2 0.000172 18-Sep K.GNEFEDYC[160.03]LK[136.11].R "sp|P26196|DDX6_HUMAN,tr|Q8IV96|Q8IV96_HUMAN" 2 1281.5427 1.13 31419 15993 2 1281.542779 641.7786 Probable ATP-dependent RNA helicase DDX6 OS=Homo sapiens OX=9606 GN=DDX6 PE=1 SV=2 4.14 2884.7 - 1.01E+06 - - - 0.0593 - 2.117 0.52 - 397.7 1 2 0 0.0001 10 0 0 0 8.57E+07 7.62E+07 - - - 4.9752 1 221125_WJC_METTL3_EV_vs_WT_F03.15994.15994.2 9.47E-10 26-Dec R.TVYGGGC[160.03]SEMLMAH.A "sp|P78371|TCPB_HUMAN,tr|F5GWF6|F5GWF6_HUMAN" 2 1511.6207 - 31420 15994 2 1511.620071 756.8176 T-complex protein 1 subunit beta OS=Homo sapiens OX=9606 GN=CCT2 PE=1 SV=4 5.21 2884.8 - 832688 - - - -0.4201 - 2.501 0.696 - 311.1 1 1 0 -0.0006 14 0 0 0 - - - - - 6.4818 0.9998 221125_WJC_METTL3_EV_vs_WT_F03.15996.15996.3 0.00278 Dec-48 K.AWLMSDKTDLEAK.K sp|P33908|MA1A1_HUMAN 1 1506.7388 0.03 31422 15996 3 1506.740099 503.2536 "Mannosyl-oligosaccharide 1,2-alpha-mannosidase IA OS=Homo sapiens OX=9606 GN=MAN1A1 PE=1 SV=3" 4.56 2885 - 410602 - - - 0.8422 - 2.574 0.442 - 198.2 1 2 1 0.0013 13 0 0 0 6.54E+06 2.52E+08 - - - 6.0309 0.9998 221125_WJC_METTL3_EV_vs_WT_F03.16002.16002.2 8.12E-06 18-Oct K.GNEFEDYC[160.03]LK.R "sp|P26196|DDX6_HUMAN,tr|Q8IV96|Q8IV96_HUMAN" 2 1273.5285 1.13 31426 16002 2 1273.529576 637.7715 Probable ATP-dependent RNA helicase DDX6 OS=Homo sapiens OX=9606 GN=DDX6 PE=1 SV=2 4.14 2885.7 - 1.80E+06 - - - 0.8425 - 2.22 0.432 - 534.8 1 2 0 0.0011 10 0 0 0 8.57E+07 7.62E+07 - - - 4.4575 0.9998 221125_WJC_METTL3_EV_vs_WT_F03.16006.16006.4 0.00859 Dec-78 R.YVPVRPRPPITLLR.H "sp|Q9H0E3|SP130_HUMAN,tr|A0A2R8YDB8|A0A2R8YDB8_HUMAN,tr|H7BXF5|H7BXF5_HUMAN" 3 1676.025 1.75 31430 16006 4 1676.022235 420.0135 Histone deacetylase complex subunit SAP130 OS=Homo sapiens OX=9606 GN=SAP130 PE=1 SV=1 11.71 2886.2 - 677601 - - - -1.6378 - 1.91 0.394 - 72.8 1 2 0 -0.0027 14 0 0 0 7.99E+06 4.58E+06 - - - 2.8901 1 221125_WJC_METTL3_EV_vs_WT_F03.16007.16007.2 3.46E-09 16/28 K.TPPGVSAPTEPLLC[160.03]K.F "sp|P29558|RBMS1_HUMAN,tr|E7ETU5|E7ETU5_HUMAN,tr|F6Y5H0|F6Y5H0_HUMAN" 3 1565.8123 1.9 31431 16007 2 1565.814046 783.9134 "RNA-binding motif, single-stranded-interacting protein 1 OS=Homo sapiens OX=9606 GN=RBMS1 PE=1 SV=3" 5.66 2886.4 - 628148 - - - 1.0959 - 2.692 0.634 - 576.3 1 2 0 0.0017 15 0 0 0 6.73E+07 3.54E+07 - - - 6.1578 0.9263 221125_WJC_METTL3_EV_vs_WT_F03.16009.16009.3 1.13 Aug-36 R.LVNHFVEEFK[136.11].R "sp|P0DMV8|HS71A_HUMAN,sp|P0DMV9|HS71B_HUMAN,tr|V9GZ37|V9GZ37_HUMAN,tr|A0A0G2JIW1|A0A0G2JIW1_HUMAN" 4 1268.6645 0.15 31433 16009 3 1268.663769 423.8954 Heat shock 70 kDa protein 1A OS=Homo sapiens OX=9606 GN=HSPA1A PE=1 SV=1 5.4 2886.6 - 449440 - - - -0.5549 - 1.313 0.116 - 78.1 1 2 0 -0.0007 10 0 0 0 1.24E+06 8.43E+06 - - - 0.6284 1 221125_WJC_METTL3_EV_vs_WT_F03.16014.16014.2 1.58E-09 16/24 K.GMAAAGNYAWVNR.S sp|Q9Y3I0|RTCB_HUMAN 1 1379.6405 1.57 31437 16014 2 1379.639594 690.8275 RNA-splicing ligase RtcB homolog OS=Homo sapiens OX=9606 GN=RTCB PE=1 SV=1 8.75 2887.2 - 4.89E+06 - - - -0.6234 - 3.104 0.659 - 1329.9 1 2 0 -0.0009 13 0 0 0 7.41E+07 4.73E+07 - - - 6.8152 0.9298 221125_WJC_METTL3_EV_vs_WT_F03.16016.16016.2 0.245 18-Aug K.DHTPSQELAL.T "sp|Q86U44|MTA70_HUMAN,tr|H0YFV6|H0YFV6_HUMAN" 2 1109.5353 - 31438 16016 2 1109.53272 555.7749 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 4.35 2887.4 - 5.89E+06 - - - -2.328 - 1.848 0.319 - 179.4 1 1 0 -0.0026 10 0 0 0 - - - - - 3.1105 0.9998 221125_WJC_METTL3_EV_vs_WT_F03.16017.16017.2 0.00114 20-Oct K.AVDEAADALLK.A "sp|Q16891|MIC60_HUMAN,tr|B9A067|B9A067_HUMAN,tr|C9J406|C9J406_HUMAN,tr|H7C463|H7C463_HUMAN" 4 1114.587 1.15 31439 16017 2 1114.587943 558.3008 MICOS complex subunit MIC60 OS=Homo sapiens OX=9606 GN=IMMT PE=1 SV=1 4.03 2887.5 - 2.60E+06 - - - 0.8425 - 2.213 0.434 - 206.4 1 2 0 0.0009 11 0 0 0 3.16E+07 2.76E+07 - - - 4.3951 0.9412 221125_WJC_METTL3_EV_vs_WT_F03.16018.16018.2 0.681 18-Oct K.NLQSAEEWYK.S sp|Q16352|AINX_HUMAN 1 1266.5881 1.9 31440 16018 2 1266.592974 634.3013 Alpha-internexin OS=Homo sapiens OX=9606 GN=INA PE=1 SV=2 4.53 2887.6 - 1.84E+06 - - - 3.8742 - 1.287 0.15 - 169.4 1 2 0 0.0049 10 0 0 0 3.17E+07 1.67E+07 - - - 0.8516 0.9999 221125_WJC_METTL3_EV_vs_WT_F03.16021.16021.2 6.73E-07 14/24 K.SVFGTPTLETANK[136.11].N sp|P49792|RBP2_HUMAN 1 1371.7125 1.31 31443 16021 2 1371.71142 686.8635 E3 SUMO-protein ligase RanBP2 OS=Homo sapiens OX=9606 GN=RANBP2 PE=1 SV=2 5.72 2887.9 - 988455 - - - -0.8209 - 2.588 0.523 - 563.4 1 2 0 -0.0011 13 0 0 0 2.53E+07 1.94E+07 - - - 5.344 0.9999 221125_WJC_METTL3_EV_vs_WT_F03.16023.16023.3 0.00983 15/36 K.QLPLVKPYLR.S "sp|Q00610|CLH1_HUMAN,sp|P53675|CLH2_HUMAN,tr|J3KS13|J3KS13_HUMAN,tr|A0A087WXH4|A0A087WXH4_HUMAN,tr|A0A087WVQ6|A0A087WVQ6_HUMAN" 5 1225.7547 0.87 31445 16023 3 1225.752566 409.5922 Clathrin heavy chain 1 OS=Homo sapiens OX=9606 GN=CLTC PE=1 SV=5 9.99 2888.1 - 672347 - - - -1.7238 - 2.838 0.398 - 458.6 1 2 0 -0.0021 10 0 0 0 2.87E+07 3.31E+07 - - - 6.023 0.9999 221125_WJC_METTL3_EV_vs_WT_F03.16024.16024.2 6.80E-08 30-Dec R.LGENGLPISEDPDGPR.K sp|Q9HBE1|PATZ1_HUMAN 1 1664.8006 0.96 31446 16024 2 1664.801341 833.4076 "POZ-, AT hook-, and zinc finger-containing protein 1 OS=Homo sapiens OX=9606 GN=PATZ1 PE=1 SV=1" 3.92 2888.3 - 661073 - - - 0.4577 - 2.649 0.529 - 276.4 1 2 0 0.0008 16 0 0 0 7.28E+06 7.59E+06 - - - 5.343 0.9998 221125_WJC_METTL3_EV_vs_WT_F03.16025.16025.2 8.14E-07 28-Nov K.TPPGVSAPTEPLLC[160.03]K[136.11].F "sp|P29558|RBMS1_HUMAN,tr|E7ETU5|E7ETU5_HUMAN,tr|F6Y5H0|F6Y5H0_HUMAN" 3 1573.8265 1.93 31447 16025 2 1573.823845 787.9205 "RNA-binding motif, single-stranded-interacting protein 1 OS=Homo sapiens OX=9606 GN=RBMS1 PE=1 SV=3" 5.66 2888.4 - 641311 - - - -1.706 - 2.324 0.547 - 257.9 1 2 0 -0.0027 15 0 0 0 5.67E+07 2.94E+07 - - - 5.1536 1 221125_WJC_METTL3_EV_vs_WT_F03.16032.16032.3 5.78E-05 15/48 K.IFYPETTDIYDR[166.11]K[136.11].N "sp|P46940|IQGA1_HUMAN,tr|A0A0J9YXZ5|A0A0J9YXZ5_HUMAN" 2 1677.8369 1.99 31453 16032 3 1677.8372 560.2862 Ras GTPase-activating-like protein IQGAP1 OS=Homo sapiens OX=9606 GN=IQGAP1 PE=1 SV=1 4.56 2889 - 2.34E+06 - - - 0.174 - 2.916 0.56 - 348.8 1 2 0 0.0003 13 0 0 0 5.06E+07 2.54E+07 - - - 7.685 0.9998 221125_WJC_METTL3_EV_vs_WT_F03.16033.16033.3 2.62E-05 13/44 R.LLRDYQELMNTK.L sp|P04264|K2C1_HUMAN 1 1522.7814 1.43 31454 16033 3 1522.780083 508.6011 "Keratin, type II cytoskeletal 1 OS=Homo sapiens OX=9606 GN=KRT1 PE=1 SV=6" 6.07 2889.1 - 2.11E+06 - - - -0.8412 - 2.519 0.441 - 313.5 1 2 1 -0.0013 12 0 0 0 3.54E+08 2.47E+08 - - - 6.0172 0.9998 221125_WJC_METTL3_EV_vs_WT_F03.16034.16034.2 5.12E-06 16-Nov K.C[160.03]DTEFPNFK.Y sp|P27694|RFA1_HUMAN 1 1156.4859 1.28 31455 16034 2 1156.483386 579.2502 Replication protein A 70 kDa DNA-binding subunit OS=Homo sapiens OX=9606 GN=RPA1 PE=1 SV=2 4.37 2889.2 - 1.73E+06 - - - -2.1825 - 2.188 0.576 - 448.1 1 2 0 -0.0025 9 0 0 0 5.94E+07 4.63E+07 - - - 5.5598 0.9952 221125_WJC_METTL3_EV_vs_WT_F03.16035.16035.2 0.000249 18-Aug K.VELC[160.03]SFSGYK[136.11].L "sp|P83731|RL24_HUMAN,tr|C9JNW5|C9JNW5_HUMAN,tr|C9JXB8|C9JXB8_HUMAN" 3 1196.5627 0.88 31456 16035 2 1196.556563 599.2886 60S ribosomal protein L24 OS=Homo sapiens OX=9606 GN=RPL24 PE=1 SV=1 5.96 2889.2 - 1.40E+06 - - - -5.1372 - 1.639 0.474 - 195.1 1 2 0 -0.0061 10 0 0 0 3.27E+07 3.72E+07 - - - 3.9192 0.9998 221125_WJC_METTL3_EV_vs_WT_F03.16036.16036.3 0.00736 15/44 R.ELAVQIYEEARK.F "sp|O00571|DDX3X_HUMAN,sp|O15523|DDX3Y_HUMAN,tr|A0A2R8YFR4|A0A2R8YFR4_HUMAN,tr|A0A2R8YCW1|A0A2R8YCW1_HUMAN,tr|A0A2R8YDH3|A0A2R8YDH3_HUMAN,tr|A0A2R8YDT5|A0A2R8YDT5_HUMAN,tr|A0A2R8Y645|A0A2R8Y645_HUMAN,tr|A0A2R8YF78|A0A2R8YF78_HUMAN,tr|A0A0D9SFB3|A0A0D9SFB3_HUMAN,tr|A0A2R8YFS5|A0A2R8YFS5_HUMAN,tr|A0A0D9SF53|A0A0D9SF53_HUMAN,tr|A0A2R8Y5G6|A0A2R8Y5G6_HUMAN,tr|A0A2R8Y7T2|A0A2R8Y7T2_HUMAN,tr|A0A0D9SG12|A0A0D9SG12_HUMAN,tr|A0A2U3TZJ9|A0A2U3TZJ9_HUMAN,tr|A0A2R8Y4A4|A0A2R8Y4A4_HUMAN" 16 1447.7671 1.41 31457 16036 3 1447.765728 483.5963 ATP-dependent RNA helicase DDX3X OS=Homo sapiens OX=9606 GN=DDX3X PE=1 SV=3 4.79 2889.3 - 1.24E+06 - - - -0.9435 - 2.349 0.323 - 420.5 1 2 0 -0.0014 12 0 0 0 3.99E+07 2.83E+07 - - - 4.5079 0.9985 221125_WJC_METTL3_EV_vs_WT_F03.16038.16038.2 0.00205 20-Dec R.VAGMLQSFQGK[136.11].D "sp|P28331|NDUS1_HUMAN,tr|B4DJ81|B4DJ81_HUMAN" 2 1172.6103 1.23 31458 16038 2 1172.604862 587.3124 "NADH-ubiquinone oxidoreductase 75 kDa subunit, mitochondrial OS=Homo sapiens OX=9606 GN=NDUFS1 PE=1 SV=3" 8.72 2889.5 - 1.68E+06 - - - -4.6622 - 2.481 0.505 - 499.7 1 2 0 -0.0055 11 0 0 0 2.35E+07 1.92E+07 - - - 5.2274 0.9989 221125_WJC_METTL3_EV_vs_WT_F03.16040.16040.2 0.00365 24-Nov R.C[160.03]LAENAGDVAFVK.D "sp|P02788|TRFL_HUMAN,tr|E7EQB2|E7EQB2_HUMAN,tr|E7ER44|E7ER44_HUMAN" 3 1392.6708 43.21 31459 16040 2 1392.669327 697.3427 Lactotransferrin OS=Homo sapiens OX=9606 GN=LTF PE=1 SV=6 4.37 2889.8 - 2.74E+06 - - - -1.0225 - 2.175 0.207 - 247.7 2 2 0 -0.0014 13 0 0 0 3.87E+07 8.95E+05 - - - 2.4293 0.9999 221125_WJC_METTL3_EV_vs_WT_F03.16043.16043.2 7.26E-05 16-Oct K.C[160.03]DTEFPNFK[136.11].Y sp|P27694|RFA1_HUMAN 1 1164.5001 1.28 31462 16043 2 1164.499594 583.2573 Replication protein A 70 kDa DNA-binding subunit OS=Homo sapiens OX=9606 GN=RPA1 PE=1 SV=2 4.37 2889.9 - 1.22E+06 - - - -0.4431 - 1.794 0.528 - 398.8 1 2 0 -0.0005 9 0 0 0 5.94E+07 4.63E+07 - - - 4.6315 0.9775 221125_WJC_METTL3_EV_vs_WT_F03.16044.16044.2 0.00282 22-Sep K.STPVTVVLPDTK.G sp|Q15029|U5S1_HUMAN 1 1255.7024 1.86 31463 16044 2 1255.707039 628.8585 116 kDa U5 small nuclear ribonucleoprotein component OS=Homo sapiens OX=9606 GN=EFTUD2 PE=1 SV=1 5.55 2890.1 - 809681 - - - 3.7198 - 1.838 0.133 - 222.6 2 2 0 0.0047 12 0 0 0 2.33E+08 1.25E+08 - - - 1.4889 1 221125_WJC_METTL3_EV_vs_WT_F03.16049.16049.2 0.000361 14/28 K.VALVYGQMNEPPGAR.A "sp|P06576|ATPB_HUMAN,tr|F8W0P7|F8W0P7_HUMAN,tr|H0YH81|H0YH81_HUMAN" 3 1600.8032 1.91 31467 16049 2 1600.804714 801.4089 "ATP synthase subunit beta, mitochondrial OS=Homo sapiens OX=9606 GN=ATP5F1B PE=1 SV=3" 5.97 2890.8 - 1.43E+06 - - - 0.9695 - 2.966 0.589 - 674.5 1 2 0 0.0016 15 0 0 0 4.01E+07 2.09E+07 - - - 6.0638 0.9942 221125_WJC_METTL3_EV_vs_WT_F03.16051.16051.2 1.62E-07 22-Nov R.MDSFDEDLARPS.G "sp|Q9Y2W1|TR150_HUMAN,tr|A0A3B3ITZ9|A0A3B3ITZ9_HUMAN" 2 1381.582 3.23 31468 16051 2 1381.580663 691.7983 Thyroid hormone receptor-associated protein 3 OS=Homo sapiens OX=9606 GN=THRAP3 PE=1 SV=2 3.84 2891 - 6.81E+06 - - - -0.9641 - 2.632 0.559 - 523.8 1 1 0 -0.0013 12 0 0 0 9.30E+07 2.88E+07 - - - 5.7157 0.9681 221125_WJC_METTL3_EV_vs_WT_F03.16052.16052.3 0.22 Nov-44 R.ELAVQIYEEAR[166.11]K[136.11].F "sp|O00571|DDX3X_HUMAN,sp|O15523|DDX3Y_HUMAN,tr|A0A2R8YFR4|A0A2R8YFR4_HUMAN,tr|A0A2R8YCW1|A0A2R8YCW1_HUMAN,tr|A0A2R8YDH3|A0A2R8YDH3_HUMAN,tr|A0A2R8YDT5|A0A2R8YDT5_HUMAN,tr|A0A2R8Y645|A0A2R8Y645_HUMAN,tr|A0A2R8YF78|A0A2R8YF78_HUMAN,tr|A0A0D9SFB3|A0A0D9SFB3_HUMAN,tr|A0A2R8YFS5|A0A2R8YFS5_HUMAN,tr|A0A0D9SF53|A0A0D9SF53_HUMAN,tr|A0A2R8Y5G6|A0A2R8Y5G6_HUMAN,tr|A0A2R8Y7T2|A0A2R8Y7T2_HUMAN,tr|A0A0D9SG12|A0A0D9SG12_HUMAN,tr|A0A2U3TZJ9|A0A2U3TZJ9_HUMAN,tr|A0A2R8Y4A4|A0A2R8Y4A4_HUMAN" 16 1465.7896 1.47 31469 16052 3 1465.794564 489.6038 ATP-dependent RNA helicase DDX3X OS=Homo sapiens OX=9606 GN=DDX3X PE=1 SV=3 4.79 2891.1 - 2.27E+06 - - - 3.4111 - 1.992 0.147 - 152 1 2 0 0.005 12 0 0 0 4.18E+07 2.85E+07 - - - 2.0877 0.9999 221125_WJC_METTL3_EV_vs_WT_F03.16054.16054.2 0.00185 18-Oct K.ISEEC[160.03]IAQWK.Q "sp|P54577|SYYC_HUMAN,tr|A0A6Q8PFX2|A0A6Q8PFX2_HUMAN" 2 1262.5965 0.69 31471 16054 2 1262.59612 632.3055 "Tyrosine--tRNA ligase, cytoplasmic OS=Homo sapiens OX=9606 GN=YARS1 PE=1 SV=4" 4.53 2891.2 - 1.97E+06 - - - -0.3192 - 2.111 0.491 - 524.5 1 2 0 -0.0004 10 0 0 0 2.31E+07 3.34E+07 - - - 4.753 0.9994 221125_WJC_METTL3_EV_vs_WT_F03.16055.16055.2 7.86E-05 18-Sep R.SFFSVESGTK[136.11].M sp|Q14966|ZN638_HUMAN 1 1095.5328 0.81 31472 16055 2 1095.53041 548.7737 Zinc finger protein 638 OS=Homo sapiens OX=9606 GN=ZNF638 PE=1 SV=2 5.72 2891.3 - 1.64E+06 - - - -2.1725 - 1.697 0.45 - 220.2 1 2 0 -0.0024 10 0 0 0 3.18E+07 3.92E+07 - - - 3.8402 0.9975 221125_WJC_METTL3_EV_vs_WT_F03.16056.16056.2 0.00604 16/22 R.LLRDYQELMNTK.L sp|P04264|K2C1_HUMAN 1 1522.7814 3.3 31473 16056 2 1522.784227 762.398 "Keratin, type II cytoskeletal 1 OS=Homo sapiens OX=9606 GN=KRT1 PE=1 SV=6" 6.07 2891.4 - 1.25E+06 - - - 1.8801 - 3.052 0.431 - 861.4 1 2 1 0.0029 12 0 0 0 4.48E+07 1.36E+07 - - - 5.1593 0.9993 221125_WJC_METTL3_EV_vs_WT_F03.16058.16058.3 0.0163 Dec-40 R.VQIEHISSLIK[136.11].L sp|O00231|PSD11_HUMAN 1 1273.7485 0.59 31475 16058 3 1273.749677 425.5901 26S proteasome non-ATPase regulatory subunit 11 OS=Homo sapiens OX=9606 GN=PSMD11 PE=1 SV=3 6.72 2891.7 - 594967 - - - 0.895 - 2.025 0.279 - 231.9 1 2 0 0.0011 11 0 0 0 2.29E+07 3.90E+07 - - - 3.6547 1 221125_WJC_METTL3_EV_vs_WT_F03.16065.16065.3 3.91E-11 15/52 K.HIGLVYSGMGPDYR[166.11].V "sp|P25787|PSA2_HUMAN,tr|A0A024RA52|A0A024RA52_HUMAN,tr|A0A7I2V2H3|A0A7I2V2H3_HUMAN" 3 1573.7587 0.7 31480 16065 3 1573.753986 525.5935 Proteasome subunit alpha type-2 OS=Homo sapiens OX=9606 GN=PSMA2 PE=1 SV=2 6.74 2892.5 - 2.73E+06 - - - -2.975 - 2.934 0.668 - 359.6 1 2 0 -0.0047 14 0 0 0 2.01E+07 2.85E+07 - - - 8.8467 0.9942 221125_WJC_METTL3_EV_vs_WT_F03.16066.16066.2 4.97E-05 22-Oct R.MDSFDEDLAR[166.11]PS.G "sp|Q9Y2W1|TR150_HUMAN,tr|A0A3B3ITZ9|A0A3B3ITZ9_HUMAN" 2 1391.5903 3.23 31481 16066 2 1391.591048 696.8024 Thyroid hormone receptor-associated protein 3 OS=Homo sapiens OX=9606 GN=THRAP3 PE=1 SV=2 3.84 2892.5 - 2.26E+06 - - - 0.5627 - 2.489 0.552 - 516 1 1 0 0.0008 12 0 0 0 9.30E+07 2.88E+07 - - - 5.5171 0.9998 221125_WJC_METTL3_EV_vs_WT_F03.16067.16067.2 1.46E-07 18-Sep R.SFFSVESGTK.M sp|Q14966|ZN638_HUMAN 1 1087.5186 0.8 31482 16067 2 1087.518278 544.7666 Zinc finger protein 638 OS=Homo sapiens OX=9606 GN=ZNF638 PE=1 SV=2 5.72 2892.6 - 2.14E+06 - - - -0.2869 - 1.763 0.43 - 206.7 1 2 0 -0.0003 10 0 0 0 3.07E+07 3.86E+07 - - - 3.7996 0.9998 221125_WJC_METTL3_EV_vs_WT_F03.16068.16068.2 0.253 20-Dec K.SVEEISTLVQK[136.11].L "sp|Q8N983|RM43_HUMAN,tr|B1AL05|B1AL05_HUMAN,tr|H0YBU8|H0YBU8_HUMAN,tr|H0Y6Y8|H0Y6Y8_HUMAN" 4 1239.6802 0.95 31483 16068 2 1239.681629 620.8474 "39S ribosomal protein L43, mitochondrial OS=Homo sapiens OX=9606 GN=MRPL43 PE=1 SV=1" 4.53 2892.7 - 1.44E+06 - - - 1.1664 - 2.729 0.394 - 407 1 2 0 0.0014 11 0 0 0 1.81E+07 1.90E+07 - - - 4.6665 1 221125_WJC_METTL3_EV_vs_WT_F03.16069.16069.3 9.95E-05 14/40 R.VQIEHISSLIK.L sp|O00231|PSD11_HUMAN 1 1265.7343 0.59 31484 16069 3 1265.733807 422.9187 26S proteasome non-ATPase regulatory subunit 11 OS=Homo sapiens OX=9606 GN=PSMD11 PE=1 SV=3 6.72 2892.9 - 1.12E+06 - - - -0.4187 - 2.53 0.432 - 305.1 1 2 0 -0.0005 11 0 0 0 2.29E+07 3.90E+07 - - - 5.9931 0.9999 221125_WJC_METTL3_EV_vs_WT_F03.16071.16071.2 1.19E-06 13/24 R.VGVPTVDLDAQGR.A sp|O60306|AQR_HUMAN 1 1325.6939 0.71 31486 16071 2 1325.694827 663.8542 RNA helicase aquarius OS=Homo sapiens OX=9606 GN=AQR PE=1 SV=4 4.21 2893.1 - 733554 - - - 0.6774 - 2.65 0.512 - 648.2 1 2 0 0.0009 13 0 0 0 2.27E+07 3.21E+07 - - - 5.3236 0.9995 221125_WJC_METTL3_EV_vs_WT_F03.16073.16073.2 4.15E-06 18/28 K.ALSAAVADSLTNSPR[166.11].D "sp|Q14687|GSE1_HUMAN,tr|H7C3B5|H7C3B5_HUMAN" 2 1481.7713 1.27 31488 16073 2 1481.766485 741.8929 Genetic suppressor element 1 OS=Homo sapiens OX=9606 GN=GSE1 PE=1 SV=3 5.88 2893.4 - 653870 - - - -3.2772 - 3.183 0.486 - 1207.8 1 2 0 -0.0049 15 0 0 0 8.23E+06 6.49E+06 - - - 5.4756 0.9996 221125_WJC_METTL3_EV_vs_WT_F03.16075.16075.2 0.00169 20-Sep R.NLPLPPPPPPR[166.11].G "sp|P61978|HNRPK_HUMAN,tr|Q5T6W2|Q5T6W2_HUMAN" 2 1203.7003 1.46 31489 16075 2 1203.699282 602.8575 Heterogeneous nuclear ribonucleoprotein K OS=Homo sapiens OX=9606 GN=HNRNPK PE=1 SV=1 9.75 2893.6 - 1.21E+06 - - - -0.8856 - 1.819 0.368 - 235.6 1 2 0 -0.0011 11 0 0 0 3.73E+07 2.56E+07 - - - 3.3772 0.9999 221125_WJC_METTL3_EV_vs_WT_F03.16077.16077.2 0.000454 22-Dec R.AEITDAEGLGLK[136.11].L "sp|Q14203|DCTN1_HUMAN,tr|A0A804CDA6|A0A804CDA6_HUMAN,tr|E7EX90|E7EX90_HUMAN,tr|A0A7P0Z4C3|A0A7P0Z4C3_HUMAN" 4 1223.6489 1.82 31490 16077 2 1223.648843 612.8317 Dynactin subunit 1 OS=Homo sapiens OX=9606 GN=DCTN1 PE=1 SV=3 4.14 2893.8 - 6.72E+06 - - - -0.0327 - 2.395 0.52 - 466.6 1 2 0 0 12 0 0 0 2.93E+08 1.61E+08 - - - 5.1797 0.9974 221125_WJC_METTL3_EV_vs_WT_F03.16078.16078.3 9.96E-07 16/44 R.YGVIILDEAHER.T sp|O43143|DHX15_HUMAN 1 1413.7252 1.1 31491 16078 3 1413.718482 472.249 Pre-mRNA-splicing factor ATP-dependent RNA helicase DHX15 OS=Homo sapiens OX=9606 GN=DHX15 PE=1 SV=2 4.65 2893.8 - 6.71E+06 - - - -4.7725 - 2.845 0.283 - 282.3 1 2 0 -0.0067 12 0 0 0 1.57E+08 1.42E+08 - - - 4.5914 0.9997 221125_WJC_METTL3_EV_vs_WT_F03.16081.16081.2 0.0197 16-Sep K.ESYSIYVYK.V "sp|Q8N257|H2B3B_HUMAN,sp|P33778|H2B1B_HUMAN,sp|Q6DN03|H2B2C_HUMAN,sp|P23527|H2B1O_HUMAN,sp|Q6DRA6|H2B2D_HUMAN,sp|Q16778|H2B2E_HUMAN,sp|P06899|H2B1J_HUMAN" 7 1150.5546 0.97 31494 16081 2 1150.554442 576.2846 Histone H2B type 3-B OS=Homo sapiens OX=9606 GN=H2BU1 PE=1 SV=3 6.1 2894.1 - 1.27E+06 - - - -0.173 - 1.708 0.38 - 232.1 1 2 0 -0.0002 9 0 0 0 1.92E+08 1.98E+08 - - - 3.3963 0.9476 221125_WJC_METTL3_EV_vs_WT_F03.16083.16083.3 0.426 13/56 K.VALVYGQMNEPPGAR[166.11].A "sp|P06576|ATPB_HUMAN,tr|F8W0P7|F8W0P7_HUMAN,tr|H0YH81|H0YH81_HUMAN" 3 1610.8114 0.97 31496 16083 3 1610.807771 537.9444 "ATP synthase subunit beta, mitochondrial OS=Homo sapiens OX=9606 GN=ATP5F1B PE=1 SV=3" 5.97 2894.3 - 621465 - - - -2.2728 - 1.621 0.132 - 148.9 1 2 0 -0.0037 15 0 0 0 1.45E+07 1.50E+07 - - - 1.2711 0.9996 221125_WJC_METTL3_EV_vs_WT_F03.16084.16084.2 3.62E-05 13/24 R.LLGLGSASGSVGR[166.11].V sp|Q9BU76|MMTA2_HUMAN 1 1182.6596 1.48 31497 16084 2 1182.662731 592.3371 Multiple myeloma tumor-associated protein 2 OS=Homo sapiens OX=9606 GN=MMTAG2 PE=1 SV=1 9.75 2894.5 - 593500 - - - 2.6423 - 2.604 0.461 - 462.9 1 2 0 0.0031 13 0 0 0 1.36E+07 9.21E+06 - - - 4.9013 0.992 221125_WJC_METTL3_EV_vs_WT_F03.16085.16085.2 1.48E-05 14/28 K.VALVYGQMNEPPGAR[166.11].A "sp|P06576|ATPB_HUMAN,tr|F8W0P7|F8W0P7_HUMAN,tr|H0YH81|H0YH81_HUMAN" 3 1610.8114 1.91 31498 16085 2 1611.811802 806.413 "ATP synthase subunit beta, mitochondrial OS=Homo sapiens OX=9606 GN=ATP5F1B PE=1 SV=3" 5.97 2894.6 - 521913 - - - 621.0348 - 2.432 0.583 - 341.3 1 2 0 1.0004 15 0 0 0 4.01E+07 2.09E+07 - - - 5.2179 0.9884 221125_WJC_METTL3_EV_vs_WT_F03.16087.16087.2 0.285 14-Jun K.ELWDQFHK.L "sp|Q13207|TBX2_HUMAN,sp|O15119|TBX3_HUMAN,tr|F8WCM9|F8WCM9_HUMAN" 3 1101.5243 0.02 31500 16087 2 1101.524033 551.7694 T-box transcription factor TBX2 OS=Homo sapiens OX=9606 GN=TBX2 PE=1 SV=3 5.32 2894.9 - 507179 - - - -0.2823 - 1.113 0.156 - 85.7 1 2 0 -0.0003 8 0 0 0 5.13E+06 2.10E+08 - - - 0.516 1 221125_WJC_METTL3_EV_vs_WT_F03.16088.16088.3 0.000141 13/36 R.RLFEGNALLR.R "sp|P46781|RS9_HUMAN,tr|C9JM19|C9JM19_HUMAN,tr|B5MCT8|B5MCT8_HUMAN" 3 1187.6775 0.38 31501 16088 3 1187.676933 396.8998 40S ribosomal protein S9 OS=Homo sapiens OX=9606 GN=RPS9 PE=1 SV=3 9.6 2895 - 484828 - - - -0.4698 - 2.501 0.424 - 325.4 1 2 0 -0.0006 10 0 0 0 9.36E+06 2.46E+07 - - - 5.9442 0.9999 221125_WJC_METTL3_EV_vs_WT_F03.16089.16089.2 0.000164 13/24 R.DIEVASNPAFPQR[166.11].L "sp|P42694|HELZ_HUMAN,tr|J3QS41|J3QS41_HUMAN" 2 1452.7237 1.92 31502 16089 2 1452.722064 727.3691 Probable helicase with zinc finger domain OS=Homo sapiens OX=9606 GN=HELZ PE=1 SV=2 4.37 2895.1 - 337740 - - - -1.1007 - 2.68 0.498 - 640.4 1 2 0 -0.0016 13 0 0 0 1.25E+07 6.52E+06 - - - 5.2489 1 221125_WJC_METTL3_EV_vs_WT_F03.16090.16090.2 1.95E-07 26-Nov R.IMDSAQYAEFC[160.03]ESR[166.11].Q "sp|O75486|SUPT3_HUMAN,tr|A0A1B0GVT7|A0A1B0GVT7_HUMAN,tr|A0A6I8PRV1|A0A6I8PRV1_HUMAN" 3 1715.7159 1.57 31503 16090 2 1715.715944 858.8652 Transcription initiation protein SPT3 homolog OS=Homo sapiens OX=9606 GN=SUPT3H PE=1 SV=3 4.14 2895.2 - 253965 - - - 0.0391 - 2.265 0.658 - 325.1 1 2 0 0.0001 14 0 0 0 1.85E+06 1.18E+06 - - - 5.9526 0.9995 221125_WJC_METTL3_EV_vs_WT_F03.16092.16092.2 0.0594 16-Sep K.TLLDIDNTR.M sp|P35527|K1C9_HUMAN 1 1059.556 5980.91 31504 16092 2 1059.556182 530.7853 "Keratin, type I cytoskeletal 9 OS=Homo sapiens OX=9606 GN=KRT9 PE=1 SV=3" 4.21 2895.5 - 3.01E+06 - - - 0.1359 - 1.648 0.348 - 227.4 1 2 0 0.0001 9 0 0 0 6.02E+09 1.01E+06 - - - 3.0565 0.9961 221125_WJC_METTL3_EV_vs_WT_F03.16094.16094.2 3.95E-06 18-Nov R.VAQLEQVYIR.G sp|P62318|SMD3_HUMAN 1 1217.6768 1.37 31505 16094 2 1217.679337 609.8457 Small nuclear ribonucleoprotein Sm D3 OS=Homo sapiens OX=9606 GN=SNRPD3 PE=1 SV=1 5.97 2895.7 - 1.02E+07 - - - 2.0654 - 2.458 0.057 - 724.8 1 2 0 0.0025 10 0 0 0 1.06E+08 7.76E+07 - - - 1.9716 0.9997 221125_WJC_METTL3_EV_vs_WT_F03.16095.16095.2 0.000167 16-Jul K.ESYSIYVYK[136.11].V "sp|Q8N257|H2B3B_HUMAN,sp|P33778|H2B1B_HUMAN,sp|Q6DN03|H2B2C_HUMAN,sp|P23527|H2B1O_HUMAN,sp|Q6DRA6|H2B2D_HUMAN,sp|Q16778|H2B2E_HUMAN,sp|P06899|H2B1J_HUMAN" 7 1158.5688 0.97 31506 16095 2 1158.568909 580.2917 Histone H2B type 3-B OS=Homo sapiens OX=9606 GN=H2BU1 PE=1 SV=3 6.1 2895.7 - 6.15E+06 - - - 0.0587 - 1.605 0.454 - 128.5 1 2 0 0.0001 9 0 0 0 1.92E+08 1.98E+08 - - - 3.763 0.9998 221125_WJC_METTL3_EV_vs_WT_F03.16096.16096.2 9.03E-05 20-Sep K.QAGVFEPTIVK[136.11].V "sp|P17987|TCPA_HUMAN,tr|F5H282|F5H282_HUMAN,tr|E7EQR6|E7EQR6_HUMAN" 3 1195.6692 0.48 31507 16096 2 1195.668073 598.8419 T-complex protein 1 subunit alpha OS=Homo sapiens OX=9606 GN=TCP1 PE=1 SV=1 6 2895.8 - 4.99E+06 - - - -0.9626 - 1.899 0.48 - 320.2 1 2 0 -0.0012 11 0 0 0 2.14E+08 4.42E+08 - - - 4.3209 0.9996 221125_WJC_METTL3_EV_vs_WT_F03.16097.16097.2 0.00141 18-Sep K.ATILDLSC[160.03]NK[136.11].L sp|Q96AG4|LRC59_HUMAN 1 1141.5893 1.14 31508 16097 2 1141.588655 571.8019 Leucine-rich repeat-containing protein 59 OS=Homo sapiens OX=9606 GN=LRRC59 PE=1 SV=1 5.87 2895.8 - 4.19E+06 - - - -0.53 - 1.766 0.35 - 229.5 1 2 0 -0.0006 10 0 0 0 6.95E+07 6.12E+07 - - - 3.2134 0.9999 221125_WJC_METTL3_EV_vs_WT_F03.16100.16100.2 6.81E-07 13/24 R.TTPSYVAFTDTER[166.11].L "sp|P48741|HSP77_HUMAN,sp|P54652|HSP72_HUMAN,sp|P0DMV8|HS71A_HUMAN,sp|P34931|HS71L_HUMAN,sp|P11142|HSP7C_HUMAN,sp|P0DMV9|HS71B_HUMAN,sp|P17066|HSP76_HUMAN,tr|E9PQQ4|E9PQQ4_HUMAN,tr|E9PNE6|E9PNE6_HUMAN,tr|E9PKE3|E9PKE3_HUMAN,tr|E9PLF4|E9PLF4_HUMAN,tr|Q53FA3|Q53FA3_HUMAN,tr|E9PI65|E9PI65_HUMAN,tr|E9PK54|E9PK54_HUMAN,tr|E9PN25|E9PN25_HUMAN,tr|E9PPY6|E9PPY6_HUMAN,tr|E9PQK7|E9PQK7_HUMAN,tr|A0A0G2JIW1|A0A0G2JIW1_HUMAN" 18 1496.7023 -1 31511 16100 2 1496.703288 749.3584 Putative heat shock 70 kDa protein 7 OS=Homo sapiens OX=9606 GN=HSPA7 PE=5 SV=2 4.37 2896 - 2.37E+06 - - - 0.6875 - 2.403 0.559 - 492.9 1 2 0 0.001 13 0 0 0 0.00E+00 0.00E+00 - - - 5.4196 0.9999 221125_WJC_METTL3_EV_vs_WT_F03.16101.16101.2 5.64E-07 26-Dec K.NGIAGSSLPPPPIK.H sp|Q9Y5A9|YTHD2_HUMAN 1 1346.7558 1.53 31512 16101 2 1346.75523 674.3852 YTH domain-containing family protein 2 OS=Homo sapiens OX=9606 GN=YTHDF2 PE=1 SV=2 8.75 2896.1 - 2.30E+06 - - - -0.424 - 2.557 0.581 - 487.9 1 2 0 -0.0006 14 0 0 0 6.87E+07 4.49E+07 - - - 5.688 0.9997 221125_WJC_METTL3_EV_vs_WT_F03.16102.16102.2 0.0343 20-Oct K.FQTMSDQIIGR.L sp|O75506|HSBP1_HUMAN 1 1294.634 1.59 31513 16102 2 1294.631254 648.3243 Heat shock factor-binding protein 1 OS=Homo sapiens OX=9606 GN=HSBP1 PE=1 SV=1 5.84 2896.1 - 2.23E+06 - - - -2.0987 - 2.269 0.476 - 316.1 1 2 0 -0.0027 11 0 0 0 7.94E+07 4.98E+07 - - - 4.7724 0.9999 221125_WJC_METTL3_EV_vs_WT_F03.16103.16103.3 0.00163 13/36 R.R[166.11]LFEGNALLR[166.11].R "sp|P46781|RS9_HUMAN,tr|C9JM19|C9JM19_HUMAN,tr|B5MCT8|B5MCT8_HUMAN" 3 1207.694 0.7 31514 16103 3 1207.6939 403.572 40S ribosomal protein S9 OS=Homo sapiens OX=9606 GN=RPS9 PE=1 SV=3 9.6 2896.2 - 1.47E+06 - - - -0.1085 - 2.414 0.386 - 355.7 1 2 0 -0.0001 10 0 0 0 8.16E+06 1.17E+07 - - - 5.4172 0.9407 221125_WJC_METTL3_EV_vs_WT_F03.16104.16104.3 0.436 Aug-40 K.LPHSVLLEIQK[136.11].E sp|Q9Y617|SERC_HUMAN 1 1283.7693 2.12 31515 16104 3 1283.773445 428.9304 Phosphoserine aminotransferase OS=Homo sapiens OX=9606 GN=PSAT1 PE=1 SV=2 6.75 2896.3 - 815059 - - - 3.2498 - 1.632 0.152 - 102.4 1 2 0 0.0042 11 0 0 0 1.47E+07 6.92E+06 - - - 1.625 0.9998 221125_WJC_METTL3_EV_vs_WT_F03.16105.16105.2 0.00286 24-Dec R.DIEVASNPAFPQR.L "sp|P42694|HELZ_HUMAN,tr|J3QS41|J3QS41_HUMAN" 2 1442.7154 1.84 31516 16105 2 1442.718301 722.365 Probable helicase with zinc finger domain OS=Homo sapiens OX=9606 GN=HELZ PE=1 SV=2 4.37 2896.4 - 803323 - - - 2.0156 - 2.547 0.508 - 453.4 1 2 0 0.0029 13 0 0 0 1.16E+07 6.31E+06 - - - 5.1917 0.9896 221125_WJC_METTL3_EV_vs_WT_F03.16110.16110.2 0.162 16-Jun K.EGENIC[160.03]FEK.- tr|F2Z2A5|F2Z2A5_HUMAN 1 1124.4808 39.07 31519 16110 2 1124.478538 563.2477 DNA topoisomerase OS=Homo sapiens OX=9606 GN=TOP3B PE=1 SV=1 4.25 2897 - 5.12E+06 - - - -2.0338 - 1.148 0.23 - 100.1 1 2 0 -0.0023 9 0 0 0 8.84E+07 2.26E+06 - - - 1.1384 0.9998 221125_WJC_METTL3_EV_vs_WT_F03.16112.16112.2 1.91E-05 18-Oct K.ATILDLSC[160.03]NK.L sp|Q96AG4|LRC59_HUMAN 1 1133.5751 1.1 31521 16112 2 1133.5762 567.7948 Leucine-rich repeat-containing protein 59 OS=Homo sapiens OX=9606 GN=LRRC59 PE=1 SV=1 5.87 2897.1 - 3.45E+06 - - - 1.0057 - 2.011 0.524 - 297 1 2 0 0.0011 10 0 0 0 7.39E+07 6.74E+07 - - - 4.861 0.9999 221125_WJC_METTL3_EV_vs_WT_F03.16113.16113.2 2.63E-05 22-Dec R.YGVIILDEAHER.T sp|O43143|DHX15_HUMAN 1 1413.7252 1.12 31522 16113 2 1413.726627 707.8699 Pre-mRNA-splicing factor ATP-dependent RNA helicase DHX15 OS=Homo sapiens OX=9606 GN=DHX15 PE=1 SV=2 4.65 2897.2 - 1.52E+06 - - - 0.9889 - 2.556 0.532 - 658.3 1 2 0 0.0014 12 0 0 0 1.95E+07 1.74E+07 - - - 5.4391 0.9911 221125_WJC_METTL3_EV_vs_WT_F03.16114.16114.2 1.24E-05 18-Sep R.THNLEPYFES.F sp|P04264|K2C1_HUMAN 1 1235.5459 - 31523 16114 2 1235.546775 618.7802 "Keratin, type II cytoskeletal 1 OS=Homo sapiens OX=9606 GN=KRT1 PE=1 SV=6" 4.5 2897.3 - 1.35E+06 - - - 0.7341 - 1.669 0.583 - 196 1 1 0 0.0009 10 0 0 0 - - - - - 4.7765 0.9998 221125_WJC_METTL3_EV_vs_WT_F03.16115.16115.2 1.43E-08 13/24 R.TTPSYVAFTDTER.L "sp|P48741|HSP77_HUMAN,sp|P54652|HSP72_HUMAN,sp|P0DMV8|HS71A_HUMAN,sp|P34931|HS71L_HUMAN,sp|P11142|HSP7C_HUMAN,sp|P0DMV9|HS71B_HUMAN,sp|P17066|HSP76_HUMAN,tr|E9PQQ4|E9PQQ4_HUMAN,tr|E9PNE6|E9PNE6_HUMAN,tr|E9PKE3|E9PKE3_HUMAN,tr|E9PLF4|E9PLF4_HUMAN,tr|Q53FA3|Q53FA3_HUMAN,tr|E9PI65|E9PI65_HUMAN,tr|E9PK54|E9PK54_HUMAN,tr|E9PN25|E9PN25_HUMAN,tr|E9PPY6|E9PPY6_HUMAN,tr|E9PQK7|E9PQK7_HUMAN,tr|A0A0G2JIW1|A0A0G2JIW1_HUMAN" 18 1486.694 0.12 31524 16115 2 1486.695801 744.3543 Putative heat shock 70 kDa protein 7 OS=Homo sapiens OX=9606 GN=HSPA7 PE=5 SV=2 4.37 2897.4 - 1.19E+06 - - - 1.2188 - 2.556 0.501 - 643.7 1 2 0 0.0018 13 0 0 0 3.59E+06 3.00E+07 - - - 5.1494 0.9999 221125_WJC_METTL3_EV_vs_WT_F03.16116.16116.2 0.00219 14/22 R.YGVIILDEAHER[166.11].T sp|O43143|DHX15_HUMAN 1 1423.7335 1.12 31525 16116 2 1423.733663 712.874 Pre-mRNA-splicing factor ATP-dependent RNA helicase DHX15 OS=Homo sapiens OX=9606 GN=DHX15 PE=1 SV=2 4.65 2897.5 - 971034 - - - 0.1152 - 2.801 0.52 - 927.4 1 2 0 0.0002 12 0 0 0 1.95E+07 1.74E+07 - - - 5.5917 1 221125_WJC_METTL3_EV_vs_WT_F03.16117.16117.3 0.000195 Nov-44 K.VIGMHYFSPVDK.M "sp|P40939|ECHA_HUMAN,tr|H0YFD6|H0YFD6_HUMAN,tr|A0A2R8Y4F5|A0A2R8Y4F5_HUMAN" 3 1391.6908 0.85 31526 16117 3 1391.69128 464.9042 "Trifunctional enzyme subunit alpha, mitochondrial OS=Homo sapiens OX=9606 GN=HADHA PE=1 SV=2" 6.71 2897.6 - 839467 - - - 0.3751 - 2.315 0.467 - 152.6 1 2 0 0.0005 12 0 0 0 3.17E+07 3.72E+07 - - - 6.0732 0.9952 221125_WJC_METTL3_EV_vs_WT_F03.16118.16118.2 1.97E-06 13/24 R.MLESLSC[160.03]EC[160.03]EAIK[136.11].Q "sp|Q96EA4|SPDLY_HUMAN,tr|D6RIF7|D6RIF7_HUMAN,tr|D6RC83|D6RC83_HUMAN,tr|D6R936|D6R936_HUMAN,tr|D6REZ1|D6REZ1_HUMAN,tr|D6RIB8|D6RIB8_HUMAN" 6 1576.7027 0.04 31527 16118 2 1577.706299 789.3586 Protein Spindly OS=Homo sapiens OX=9606 GN=SPDL1 PE=1 SV=2 4.25 2897.7 - 970550 - - - 636.5481 - 2.403 0.539 - 414 1 2 0 1.0036 13 0 0 0 2.69E+05 6.66E+06 - - - 4.957 0.9998 221125_WJC_METTL3_EV_vs_WT_F03.16119.16119.2 6.57E-07 13/22 K.SFGQFNPGC[160.03]VER.V "sp|A0AV96|RBM47_HUMAN,tr|B7Z8Z7|B7Z8Z7_HUMAN,tr|D6R9D6|D6R9D6_HUMAN" 3 1396.6194 0.7 31528 16119 2 1396.617375 699.317 RNA-binding protein 47 OS=Homo sapiens OX=9606 GN=RBM47 PE=1 SV=2 5.72 2897.9 - 589593 - - - -1.4385 - 2.433 0.512 - 581.8 1 2 0 -0.002 12 0 0 0 8.62E+06 1.23E+07 - - - 5.1614 0.9991 221125_WJC_METTL3_EV_vs_WT_F03.16120.16120.2 4.67E-06 22-Oct K.IIPTLEEYQHYK.G tr|Q5T6W2|Q5T6W2_HUMAN 1 1532.7875 1.11 31529 16120 2 1532.792811 767.401 Heterogeneous nuclear ribonucleoprotein K (Fragment) OS=Homo sapiens OX=9606 GN=HNRNPK PE=1 SV=1 5.4 2898 - 543730 - - - 3.4682 - 1.972 0.511 - 339.2 1 2 0 0.0053 12 0 0 0 4.59E+06 4.16E+06 - - - 4.6003 0.9999 221125_WJC_METTL3_EV_vs_WT_F03.16121.16121.2 1.62E-07 22-Dec R.EFFYTAATNNPR.F "sp|Q49AN0|CRY2_HUMAN,sp|Q16526|CRY1_HUMAN,tr|A0A0D2X7Z3|A0A0D2X7Z3_HUMAN" 3 1429.6626 1.75 31530 16121 2 1429.660678 715.8386 Cryptochrome-2 OS=Homo sapiens OX=9606 GN=CRY2 PE=1 SV=2 6.1 2898.1 - 380248 - - - -1.3647 - 2.45 0.566 - 525.4 1 2 0 -0.002 12 0 0 0 9.33E+06 5.33E+06 - - - 5.5786 0.9998 221125_WJC_METTL3_EV_vs_WT_F03.16122.16122.2 0.00855 22-Nov K.IIPTLEEYQHYK[136.11].G tr|Q5T6W2|Q5T6W2_HUMAN 1 1540.8017 1.12 31531 16122 2 1540.80098 771.4081 Heterogeneous nuclear ribonucleoprotein K (Fragment) OS=Homo sapiens OX=9606 GN=HNRNPK PE=1 SV=1 5.4 2898.2 - 374561 - - - -0.464 - 1.911 0.42 - 336.8 1 2 0 -0.0007 12 0 0 0 2.77E+07 2.48E+07 - - - 3.8469 0.9938 221125_WJC_METTL3_EV_vs_WT_F03.16124.16124.2 1.50E-06 16/26 R.ALEEALEAKEEFER.Q sp|P35580|MYH10_HUMAN 1 1662.8101 0.94 31533 16124 2 1662.815609 832.4123 Myosin-10 OS=Homo sapiens OX=9606 GN=MYH10 PE=1 SV=3 4.21 2898.5 - 371169 - - - 3.3245 - 3.458 0.429 - 1236.7 1 2 1 0.0055 14 0 0 0 2.87E+06 3.05E+06 - - - 5.3213 0.9998 221125_WJC_METTL3_EV_vs_WT_F03.16125.16125.2 9.99E-06 26-Oct K.VLYNDLGAQVTEGK[136.11].Q sp|P46939|UTRN_HUMAN 1 1513.7868 1.26 31534 16125 2 1513.7873 757.9007 Utrophin OS=Homo sapiens OX=9606 GN=UTRN PE=1 SV=2 4.37 2898.6 - 273517 - - - 0.3481 - 2.087 0.49 - 231.7 1 2 0 0.0005 14 0 0 0 2.12E+06 1.69E+06 - - - 4.5062 1 221125_WJC_METTL3_EV_vs_WT_F03.16129.16129.3 3.64E-07 Dec-48 R.TTPSYVAFTDTER[166.11].L "sp|P48741|HSP77_HUMAN,sp|P54652|HSP72_HUMAN,sp|P0DMV8|HS71A_HUMAN,sp|P34931|HS71L_HUMAN,sp|P11142|HSP7C_HUMAN,sp|P0DMV9|HS71B_HUMAN,sp|P17066|HSP76_HUMAN,tr|E9PQQ4|E9PQQ4_HUMAN,tr|E9PNE6|E9PNE6_HUMAN,tr|E9PKE3|E9PKE3_HUMAN,tr|E9PLF4|E9PLF4_HUMAN,tr|Q53FA3|Q53FA3_HUMAN,tr|E9PI65|E9PI65_HUMAN,tr|E9PK54|E9PK54_HUMAN,tr|E9PN25|E9PN25_HUMAN,tr|E9PPY6|E9PPY6_HUMAN,tr|E9PQK7|E9PQK7_HUMAN,tr|A0A0G2JIW1|A0A0G2JIW1_HUMAN" 18 1496.7023 0.15 31536 16129 3 1496.703299 499.908 Putative heat shock 70 kDa protein 7 OS=Homo sapiens OX=9606 GN=HSPA7 PE=5 SV=2 4.37 2899.2 - 9.65E+06 - - - 0.6949 - 2.144 0.508 - 162.2 1 2 0 0.001 13 0 0 0 2.69E+08 1.74E+09 - - - 6.2712 0.9988 221125_WJC_METTL3_EV_vs_WT_F03.16130.16130.3 0.115 Oct-48 K.ASLASLPPLHVAK[136.11].L "sp|Q14203|DCTN1_HUMAN,tr|A0A804CDA6|A0A804CDA6_HUMAN,tr|E7EX90|E7EX90_HUMAN,tr|A0A7P0Z4C3|A0A7P0Z4C3_HUMAN,tr|E7EWF7|E7EWF7_HUMAN" 5 1310.7802 5.97 31537 16130 3 1310.780579 437.934 Dynactin subunit 1 OS=Homo sapiens OX=9606 GN=DCTN1 PE=1 SV=3 8.8 2899.2 - 6.97E+06 - - - 0.3105 - 1.861 0.267 - 158.5 1 2 0 0.0004 13 0 0 0 2.21E+08 3.70E+07 - - - 3.2007 0.9999 221125_WJC_METTL3_EV_vs_WT_F03.16131.16131.3 1.84E-05 20/52 R.ALEEALEAK[136.11]EEFER[166.11].Q sp|P35580|MYH10_HUMAN 1 1680.8326 1.66 31538 16131 3 1680.833097 561.2848 Myosin-10 OS=Homo sapiens OX=9606 GN=MYH10 PE=1 SV=3 4.21 2899.3 - 4.35E+06 - - - 0.3248 - 3.678 0.477 - 571 1 2 1 0.0005 14 0 0 0 5.19E+07 3.13E+07 - - - 7.319 1 221125_WJC_METTL3_EV_vs_WT_F03.16132.16132.3 0.000172 Oct-44 K.IIPTLEEYQHYK[136.11].G tr|Q5T6W2|Q5T6W2_HUMAN 1 1540.8017 0.31 31539 16132 3 1540.801773 514.6078 Heterogeneous nuclear ribonucleoprotein K (Fragment) OS=Homo sapiens OX=9606 GN=HNRNPK PE=1 SV=1 5.4 2899.3 - 4.03E+06 - - - 0.0506 - 2.354 0.494 - 117.2 1 2 0 0.0001 12 0 0 0 8.13E+07 2.66E+08 - - - 6.4206 1 221125_WJC_METTL3_EV_vs_WT_F03.16133.16133.2 5.31E-06 20-Oct K.FQTMSDQIIGR[166.11].L sp|O75506|HSBP1_HUMAN 1 1304.6422 1.57 31540 16133 2 1304.642187 653.3284 Heat shock factor-binding protein 1 OS=Homo sapiens OX=9606 GN=HSBP1 PE=1 SV=1 5.84 2899.3 - 4.02E+06 - - - -0.0414 - 2.32 0.603 - 320.7 1 2 0 -0.0001 11 0 0 0 7.94E+07 5.06E+07 - - - 5.7714 0.9982 221125_WJC_METTL3_EV_vs_WT_F03.16134.16134.2 8.13E-05 20-Oct R.NPEAALSPTFR[166.11].S "sp|Q86U44|MTA70_HUMAN,tr|B4E349|B4E349_HUMAN,tr|F5H6D8|F5H6D8_HUMAN,tr|B4DTN4|B4DTN4_HUMAN" 4 1211.6174 0 31541 16134 2 1211.614883 606.816 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 6 2899.4 - 2.65E+06 - - - -2.0832 - 2.213 0.192 - 544.2 1 2 0 -0.0025 11 0 0 0 3.34E+05 9.68E+07 - - - 2.6072 0.8126 221125_WJC_METTL3_EV_vs_WT_F03.16135.16135.2 0.431 18-Jul F.IVQSLSSTPR.V "sp|Q8NI35|INADL_HUMAN,tr|A0A2R8Y549|A0A2R8Y549_HUMAN" 2 1086.6033 999 31542 16135 2 1086.603528 544.3089 InaD-like protein OS=Homo sapiens OX=9606 GN=PATJ PE=1 SV=3 9.75 2899.4 - 2.42E+06 - - - 0.1887 - 1.454 0.184 - 79 2 1 0 0.0002 10 0 0 0 2.30E+07 0.00E+00 - - - 1.3103 0.9994 221125_WJC_METTL3_EV_vs_WT_F03.16136.16136.2 8.18E-05 18-Nov K.SFLSQGQVLK[136.11].L "sp|P48047|ATPO_HUMAN,tr|H7C068|H7C068_HUMAN" 2 1113.6274 0.98 31543 16136 2 1113.628711 557.821 "ATP synthase subunit O, mitochondrial OS=Homo sapiens OX=9606 GN=ATP5PO PE=1 SV=1" 8.47 2899.5 - 2.24E+06 - - - 1.2141 - 2.09 0.295 - 308.1 1 2 0 0.0014 10 0 0 0 8.43E+07 8.58E+07 - - - 3.2771 1 221125_WJC_METTL3_EV_vs_WT_F03.16137.16137.2 4.06E-09 20-Nov K.VC[160.03]NYGLTFTQK.W "sp|Q9Y277|VDAC3_HUMAN,tr|E5RHE1|E5RHE1_HUMAN,tr|E5RJN6|E5RJN6_HUMAN,tr|E5RK27|E5RK27_HUMAN,tr|E5RFP6|E5RFP6_HUMAN,tr|E5RHZ6|E5RHZ6_HUMAN" 6 1329.6387 1.34 31544 16137 2 1329.639569 665.8266 Voltage-dependent anion-selective channel protein 3 OS=Homo sapiens OX=9606 GN=VDAC3 PE=1 SV=1 8.17 2899.6 - 2.11E+06 - - - 0.637 - 2.493 0.589 - 574.5 1 2 0 0.0008 11 0 0 0 2.78E+07 2.07E+07 - - - 5.8623 1 221125_WJC_METTL3_EV_vs_WT_F03.16138.16138.2 5.81E-08 13/22 K.FAESTEISELSH.N sp|O95881|TXD12_HUMAN 1 1348.6147 - 31545 16138 2 1348.615739 675.3146 Thioredoxin domain-containing protein 12 OS=Homo sapiens OX=9606 GN=TXNDC12 PE=1 SV=1 4.24 2899.7 - 1.99E+06 - - - 0.7882 - 2.34 0.627 - 519.3 1 1 0 0.0011 12 0 0 0 - - - - - 5.9086 0.9998 221125_WJC_METTL3_EV_vs_WT_F03.16139.16139.2 3.41E-05 20-Nov R.TPYGASIFQSK[136.11].E "sp|Q04727|TLE4_HUMAN,sp|Q04725|TLE2_HUMAN,sp|Q04724|TLE1_HUMAN,sp|Q04726|TLE3_HUMAN,tr|A0A0D9SES8|A0A0D9SES8_HUMAN,tr|H0YL70|H0YL70_HUMAN,tr|H0YKN8|H0YKN8_HUMAN,tr|H0YKT5|H0YKT5_HUMAN,tr|K7EMK7|K7EMK7_HUMAN,tr|H0YNI7|H0YNI7_HUMAN,tr|H0YNT2|H0YNT2_HUMAN" 11 1205.6172 1.62 31546 16139 2 1205.616105 603.8159 Transducin-like enhancer protein 4 OS=Homo sapiens OX=9606 GN=TLE4 PE=1 SV=3 8.26 2899.7 - 1.99E+06 - - - -0.8991 - 1.775 0.527 - 411.7 1 2 0 -0.0011 11 0 0 0 2.86E+07 1.76E+07 - - - 4.4853 0.9997 221125_WJC_METTL3_EV_vs_WT_F03.16140.16140.2 0.00027 14-Aug K.EC[160.03]ADLWPR[166.11].L "sp|P62829|RL23_HUMAN,tr|J3KTJ3|J3KTJ3_HUMAN" 2 1055.4734 1.05 31547 16140 2 1055.473411 528.744 60S ribosomal protein L23 OS=Homo sapiens OX=9606 GN=RPL23 PE=1 SV=1 4.37 2899.8 - 1.75E+06 - - - 0.0246 - 1.745 0.384 - 413.4 1 2 0 0 8 0 0 0 7.74E+07 7.36E+07 - - - 3.5564 0.9984 221125_WJC_METTL3_EV_vs_WT_F03.16141.16141.2 0.000317 20-Sep K.VC[160.03]NYGLTFTQK[136.11].W "sp|Q9Y277|VDAC3_HUMAN,tr|E5RHE1|E5RHE1_HUMAN,tr|E5RJN6|E5RJN6_HUMAN,tr|E5RK27|E5RK27_HUMAN,tr|E5RFP6|E5RFP6_HUMAN,tr|E5RHZ6|E5RHZ6_HUMAN" 6 1337.6529 1.34 31548 16141 2 1337.647325 669.8337 Voltage-dependent anion-selective channel protein 3 OS=Homo sapiens OX=9606 GN=VDAC3 PE=1 SV=1 8.17 2899.9 - 1.65E+06 - - - -4.1842 - 2.1 0.471 - 342.7 1 2 0 -0.0056 11 0 0 0 2.78E+07 2.07E+07 - - - 4.5252 0.9996 221125_WJC_METTL3_EV_vs_WT_F03.16150.16150.2 0.0366 13/22 R.MPVSIDLENSQK[136.11].L sp|Q96T58|MINT_HUMAN 1 1367.6846 1.52 31556 16150 2 1367.681798 684.8496 Msx2-interacting protein OS=Homo sapiens OX=9606 GN=SPEN PE=1 SV=1 4.37 2900.8 - 1.16E+06 - - - -2.0604 - 2.588 0.391 - 628.5 1 2 0 -0.0028 12 0 0 0 3.07E+07 2.03E+07 - - - 4.43 0.9984 221125_WJC_METTL3_EV_vs_WT_F03.16151.16151.2 9.59E-07 22-Dec R.EFFYTAATNNPR[166.11].F "sp|Q49AN0|CRY2_HUMAN,sp|Q16526|CRY1_HUMAN,tr|A0A0D2X7Z3|A0A0D2X7Z3_HUMAN" 3 1439.6709 1.95 31557 16151 2 1439.664095 720.8427 Cryptochrome-2 OS=Homo sapiens OX=9606 GN=CRY2 PE=1 SV=2 6.1 2901 - 541144 - - - -4.7261 - 2.217 0.551 - 502.5 1 2 0 -0.0068 12 0 0 0 1.33E+07 6.86E+06 - - - 5.2034 1 221125_WJC_METTL3_EV_vs_WT_F03.16152.16152.3 3.70E-06 Dec-48 R.TTPSYVAFTDTER.L "sp|P48741|HSP77_HUMAN,sp|P54652|HSP72_HUMAN,sp|P0DMV8|HS71A_HUMAN,sp|P34931|HS71L_HUMAN,sp|P11142|HSP7C_HUMAN,sp|P0DMV9|HS71B_HUMAN,sp|P17066|HSP76_HUMAN,tr|E9PQQ4|E9PQQ4_HUMAN,tr|E9PNE6|E9PNE6_HUMAN,tr|E9PKE3|E9PKE3_HUMAN,tr|E9PLF4|E9PLF4_HUMAN,tr|Q53FA3|Q53FA3_HUMAN,tr|E9PI65|E9PI65_HUMAN,tr|E9PK54|E9PK54_HUMAN,tr|E9PN25|E9PN25_HUMAN,tr|E9PPY6|E9PPY6_HUMAN,tr|E9PQK7|E9PQK7_HUMAN,tr|A0A0G2JIW1|A0A0G2JIW1_HUMAN" 18 1486.694 0.15 31558 16152 3 1486.69332 496.5719 Putative heat shock 70 kDa protein 7 OS=Homo sapiens OX=9606 GN=HSPA7 PE=5 SV=2 4.37 2901 - 3.22E+06 - - - -0.45 - 2.145 0.49 - 182.7 1 2 0 -0.0007 13 0 0 0 2.69E+08 1.74E+09 - - - 6.0719 0.9669 221125_WJC_METTL3_EV_vs_WT_F03.16154.16154.2 0.000552 26-Dec K.NGIAGSSLPPPPIK[136.11].H sp|Q9Y5A9|YTHD2_HUMAN 1 1354.77 1.08 31560 16154 2 1355.773299 678.3923 YTH domain-containing family protein 2 OS=Homo sapiens OX=9606 GN=YTHDF2 PE=1 SV=2 8.75 2901.1 - 1.93E+06 - - - 740.567 - 2.377 0.221 - 468.1 1 2 0 1.0033 14 0 0 0 5.84E+07 5.41E+07 - - - 2.5311 0.8593 221125_WJC_METTL3_EV_vs_WT_F03.16155.16155.2 0.0704 22-Sep R.FSDGAASIQAFK.A "sp|Q9Y2K2|SIK3_HUMAN,tr|H0Y4E8|H0Y4E8_HUMAN" 2 1240.6088 2.64 31561 16155 2 1240.613768 621.3117 Serine\threonine-protein kinase SIK3 OS=Homo sapiens OX=9606 GN=SIK3 PE=1 SV=4 5.84 2901.2 - 1.63E+06 - - - 4.0029 - 1.429 0.058 - 114.8 2 2 0 0.005 12 0 0 0 3.43E+07 1.30E+07 - - - 0.2726 0.9999 221125_WJC_METTL3_EV_vs_WT_F03.16156.16156.2 3.63E-07 14/26 K.AGVQSGTNALLVVK[136.11].H sp|Q8N7H5|PAF1_HUMAN 1 1363.7915 2.94 31562 16156 2 1363.791193 682.903 RNA polymerase II-associated factor 1 homolog OS=Homo sapiens OX=9606 GN=PAF1 PE=1 SV=2 8.8 2901.3 - 1.48E+06 - - - -0.1994 - 2.512 0.569 - 548.5 1 2 0 -0.0003 14 0 0 0 4.99E+07 1.70E+07 - - - 5.555 1 221125_WJC_METTL3_EV_vs_WT_F03.16157.16157.2 1.65E-08 17/24 R.TTAATLMNAYSSR.S "sp|P52732|KIF11_HUMAN,tr|A0A7I2YQY4|A0A7I2YQY4_HUMAN,tr|A0A7I2V3A9|A0A7I2V3A9_HUMAN,tr|A0A7I2V3V3|A0A7I2V3V3_HUMAN" 4 1385.6609 3.87 31563 16157 2 1385.659388 693.8377 Kinesin-like protein KIF11 OS=Homo sapiens OX=9606 GN=KIF11 PE=1 SV=2 8.41 2901.4 - 1.31E+06 - - - -1.1013 - 3.107 0.613 - 1334.3 1 2 0 -0.0015 13 0 0 0 1.04E+09 2.69E+08 - - - 6.4777 0.9928 221125_WJC_METTL3_EV_vs_WT_F03.16159.16159.2 6.89E-05 16/26 R.PITPVYTVAPNVQR.L "sp|A0AV96|RBM47_HUMAN,tr|B7Z8Z7|B7Z8Z7_HUMAN" 2 1553.8566 1.67 31565 16159 2 1553.85599 777.9356 RNA-binding protein 47 OS=Homo sapiens OX=9606 GN=RBM47 PE=1 SV=2 9.18 2901.7 - 1.03E+06 - - - -0.3784 - 2.45 0.485 - 400.6 1 1 0 -0.0006 14 0 0 0 1.85E+07 1.11E+07 - - - 4.8717 0.9508 221125_WJC_METTL3_EV_vs_WT_F03.16160.16160.3 1.39 Sep-44 K.FLVGPDGVPLR[166.11]R[166.11].Y "sp|P07203|GPX1_HUMAN,tr|A0A2R8Y6B6|A0A2R8Y6B6_HUMAN" 2 1344.7781 3.08 31566 16160 3 1344.776726 449.2666 Glutathione peroxidase 1 OS=Homo sapiens OX=9606 GN=GPX1 PE=1 SV=4 9.6 2901.8 - 974561 - - - -1.018 - 1.326 0.139 - 60.3 1 2 0 -0.0014 12 0 0 0 2.49E+07 8.07E+06 - - - 0.8715 0.9999 221125_WJC_METTL3_EV_vs_WT_F03.16161.16161.2 2.07E-08 14/22 K.SFGQFNPGC[160.03]VER[166.11].V "sp|A0AV96|RBM47_HUMAN,tr|B7Z8Z7|B7Z8Z7_HUMAN,tr|D6R9D6|D6R9D6_HUMAN" 3 1406.6277 0.68 31567 16161 2 1406.626509 704.3211 RNA-binding protein 47 OS=Homo sapiens OX=9606 GN=RBM47 PE=1 SV=2 5.72 2901.9 - 798355 - - - -0.814 - 2.643 0.518 - 730.5 1 2 0 -0.0011 12 0 0 0 8.62E+06 1.27E+07 - - - 5.4239 0.9898 221125_WJC_METTL3_EV_vs_WT_F03.16162.16162.2 0.0252 14/26 R.ALEEALEAK[136.11]EEFER[166.11].Q sp|P35580|MYH10_HUMAN 1 1680.8326 0.94 31568 16162 2 1680.831348 841.4236 Myosin-10 OS=Homo sapiens OX=9606 GN=MYH10 PE=1 SV=3 4.21 2902 - 282330 - - - -0.7157 - 1.887 0.254 - 293.1 1 2 1 -0.0012 14 0 0 0 2.87E+06 3.05E+06 - - - 2.5101 0.9998 221125_WJC_METTL3_EV_vs_WT_F03.16165.16165.2 0.00479 16-Oct M.VNFTVDQIR[166.11].A sp|P13639|EF2_HUMAN 1 1100.5854 0.62 31569 16165 2 1100.585151 551.3 Elongation factor 2 OS=Homo sapiens OX=9606 GN=EEF2 PE=1 SV=4 5.81 2902.4 - 1.81E+07 - - - -0.2063 - 2.166 0.373 - 543.7 1 2 0 -0.0002 9 0 0 0 1.08E+08 1.74E+08 - - - 4.0319 0.9998 221125_WJC_METTL3_EV_vs_WT_F03.16166.16166.2 3.16E-05 16-Oct M.VNFTVDQIR.A sp|P13639|EF2_HUMAN 1 1090.5771 0.62 31570 16166 2 1090.576217 546.2958 Elongation factor 2 OS=Homo sapiens OX=9606 GN=EEF2 PE=1 SV=4 5.81 2902.5 - 7.34E+06 - - - -0.817 - 2.124 0.414 - 638.5 1 2 0 -0.0009 9 0 0 0 1.08E+08 1.75E+08 - - - 4.2779 1 221125_WJC_METTL3_EV_vs_WT_F03.16168.16168.2 1.98E-09 16/24 R.TTAATLMNAYSSR[166.11].S "sp|P52732|KIF11_HUMAN,tr|A0A7I2YQY4|A0A7I2YQY4_HUMAN,tr|A0A7I2V3A9|A0A7I2V3A9_HUMAN,tr|A0A7I2V3V3|A0A7I2V3V3_HUMAN" 4 1395.6692 3.87 31572 16168 2 1395.67087 698.8419 Kinesin-like protein KIF11 OS=Homo sapiens OX=9606 GN=KIF11 PE=1 SV=2 8.41 2902.6 - 2.32E+06 - - - 1.208 - 3.016 0.61 - 1111 1 2 0 0.0017 13 0 0 0 1.04E+09 2.68E+08 - - - 6.3792 0.9999 221125_WJC_METTL3_EV_vs_WT_F03.16170.16170.2 1.09E-06 14/24 K.VQAQVIQETIVPK[136.11].E sp|Q15459|SF3A1_HUMAN 1 1459.849 0.99 31574 16170 2 1459.849781 730.9318 Splicing factor 3A subunit 1 OS=Homo sapiens OX=9606 GN=SF3A1 PE=1 SV=1 5.97 2902.8 - 2.09E+06 - - - 0.5487 - 2.787 0.543 - 626.4 1 2 0 0.0008 13 0 0 0 1.09E+08 1.10E+08 - - - 5.682 0.9999 221125_WJC_METTL3_EV_vs_WT_F03.16172.16172.2 0.000153 15/24 K.VQAQVIQETIVPK.E sp|Q15459|SF3A1_HUMAN 1 1451.8348 0.99 31576 16172 2 1451.835513 726.9247 Splicing factor 3A subunit 1 OS=Homo sapiens OX=9606 GN=SF3A1 PE=1 SV=1 5.97 2903.1 - 1.94E+06 - - - 0.5049 - 3.028 0.507 - 822.1 1 2 0 0.0007 13 0 0 0 1.09E+08 1.10E+08 - - - 5.6289 1 221125_WJC_METTL3_EV_vs_WT_F03.16177.16177.2 2.78E-07 20-Nov T.PSYVAFTDTER[166.11].L "sp|P48741|HSP77_HUMAN,sp|P54652|HSP72_HUMAN,sp|P0DMV8|HS71A_HUMAN,sp|P34931|HS71L_HUMAN,sp|P11142|HSP7C_HUMAN,sp|P0DMV9|HS71B_HUMAN,sp|P17066|HSP76_HUMAN,tr|E9PQQ4|E9PQQ4_HUMAN,tr|E9PNE6|E9PNE6_HUMAN,tr|E9PKE3|E9PKE3_HUMAN,tr|E9PLF4|E9PLF4_HUMAN,tr|Q53FA3|Q53FA3_HUMAN,tr|E9PI65|E9PI65_HUMAN,tr|E9PK54|E9PK54_HUMAN,tr|E9PN25|E9PN25_HUMAN,tr|E9PPY6|E9PPY6_HUMAN,tr|E9PQK7|E9PQK7_HUMAN,tr|A0A0G2JIW1|A0A0G2JIW1_HUMAN" 18 1294.6069 0.15 31579 16177 2 1294.605246 648.3107 Putative heat shock 70 kDa protein 7 OS=Homo sapiens OX=9606 GN=HSPA7 PE=5 SV=2 4.37 2903.7 - 5.13E+06 - - - -1.2792 - 2.507 0.618 - 540.6 1 1 0 -0.0017 11 0 0 0 1.82E+07 1.22E+08 - - - 6.0914 0.9999 221125_WJC_METTL3_EV_vs_WT_F03.16179.16179.2 0.00115 13/20 K.NMDAIIVDSEK.T "sp|Q14683|SMC1A_HUMAN,tr|G8JLG1|G8JLG1_HUMAN,tr|A0A6Q8PHC3|A0A6Q8PHC3_HUMAN" 3 1233.5911 2.4 31581 16179 2 1233.589935 617.8028 Structural maintenance of chromosomes protein 1A OS=Homo sapiens OX=9606 GN=SMC1A PE=1 SV=2 4.03 2903.9 - 2.29E+06 - - - -0.9468 - 2.495 0.462 - 682.1 1 2 0 -0.0012 11 0 0 0 8.52E+07 3.56E+07 - - - 4.9263 1 221125_WJC_METTL3_EV_vs_WT_F03.16180.16180.2 5.26E-08 14/22 K.YQIDPDAC[160.03]FSAK.V sp|P21796|VDAC1_HUMAN 1 1413.6235 1.45 31582 16180 2 1413.620303 707.819 Voltage-dependent anion-selective channel protein 1 OS=Homo sapiens OX=9606 GN=VDAC1 PE=1 SV=2 4.21 2904 - 2.17E+06 - - - -2.2375 - 2.335 0.642 - 450.3 1 2 0 -0.0032 12 0 0 0 1.67E+08 1.15E+08 - - - 6.0131 0.9984 221125_WJC_METTL3_EV_vs_WT_F03.16187.16187.2 0.0166 18-Sep R.GIFTSEIGTK.Q sp|P78527|PRKDC_HUMAN 1 1051.555 0.66 31589 16187 2 1051.552784 526.7848 DNA-dependent protein kinase catalytic subunit OS=Homo sapiens OX=9606 GN=PRKDC PE=1 SV=3 6 2904.8 - 897355 - - - -2.0845 - 1.507 0.342 - 195.2 1 2 0 -0.0022 10 0 0 0 4.24E+06 6.40E+06 - - - 2.7111 1 221125_WJC_METTL3_EV_vs_WT_F03.16190.16190.3 7.40E-06 17/48 R.TTAATLMNAYSSR.S "sp|P52732|KIF11_HUMAN,tr|A0A7I2YQY4|A0A7I2YQY4_HUMAN,tr|A0A7I2V3A9|A0A7I2V3A9_HUMAN,tr|A0A7I2V3V3|A0A7I2V3V3_HUMAN" 4 1385.6609 4.19 31590 16190 3 1385.658001 462.8942 Kinesin-like protein KIF11 OS=Homo sapiens OX=9606 GN=KIF11 PE=1 SV=2 8.41 2905.2 - 4.96E+06 - - - -2.1022 - 2.919 0.519 - 518.8 1 2 0 -0.0029 13 0 0 0 1.62E+08 3.86E+07 - - - 7.23 0.9998 221125_WJC_METTL3_EV_vs_WT_F03.16193.16193.2 4.32E-07 13/20 R.SFVDAEVDVTR[166.11].D "sp|Q6P1J9|CDC73_HUMAN,tr|A0A2R8YHB3|A0A2R8YHB3_HUMAN,tr|A0A1B0GUB2|A0A1B0GUB2_HUMAN,tr|A0A3B3IRP5|A0A3B3IRP5_HUMAN" 4 1246.6069 1.27 31593 16193 2 1246.604694 624.3107 Parafibromin OS=Homo sapiens OX=9606 GN=CDC73 PE=1 SV=1 4.03 2905.6 - 3.55E+06 - - - -1.7712 - 2.331 0.517 - 562.6 1 2 0 -0.0022 11 0 0 0 5.91E+07 4.66E+07 - - - 5.1483 0.9997 221125_WJC_METTL3_EV_vs_WT_F03.16196.16196.2 0.000487 14/22 R.VINLNDNTFTEK.G "sp|P46060|RAGP1_HUMAN,tr|H0Y4Q3|H0Y4Q3_HUMAN" 2 1406.7042 1.2 31596 16196 2 1406.700942 704.3594 Ran GTPase-activating protein 1 OS=Homo sapiens OX=9606 GN=RANGAP1 PE=1 SV=1 4.37 2905.9 - 2.19E+06 - - - -2.2869 - 2.549 0.466 - 570.7 1 2 0 -0.0032 12 0 0 0 9.29E+07 7.74E+07 - - - 4.9439 0.9999 221125_WJC_METTL3_EV_vs_WT_F03.16198.16198.2 0.00114 20-Dec K.EGVEC[160.03]EVINMR.T "sp|P11177|ODPB_HUMAN,tr|C9J634|C9J634_HUMAN" 2 1334.5959 1.25 31598 16198 2 1334.596926 668.3052 "Pyruvate dehydrogenase E1 component subunit beta, mitochondrial OS=Homo sapiens OX=9606 GN=PDHB PE=1 SV=3" 4.25 2906.2 - 1.20E+06 - - - 0.7905 - 2.434 0.497 - 789.9 1 2 0 0.0011 11 0 0 0 1.79E+07 1.43E+07 - - - 5.1179 0.9999 221125_WJC_METTL3_EV_vs_WT_F03.16202.16202.2 5.00E-06 14/28 R.GPGLASGQLYSYPAR.R "sp|Q92785|REQU_HUMAN,tr|J3KMZ8|J3KMZ8_HUMAN,tr|E9PN04|E9PN04_HUMAN" 3 1535.7732 1.19 31600 16202 2 1535.770946 768.8939 Zinc finger protein ubi-d4 OS=Homo sapiens OX=9606 GN=DPF2 PE=1 SV=2 8.59 2906.7 - 1.03E+06 - - - -1.495 - 2.842 0.533 - 411.9 1 2 0 -0.0023 15 0 0 0 5.01E+07 4.21E+07 - - - 5.545 0.9995 221125_WJC_METTL3_EV_vs_WT_F03.16204.16204.3 0.000633 Nov-48 R.TTAATLMNAYSSR[166.11].S "sp|P52732|KIF11_HUMAN,tr|A0A7I2YQY4|A0A7I2YQY4_HUMAN,tr|A0A7I2V3A9|A0A7I2V3A9_HUMAN,tr|A0A7I2V3V3|A0A7I2V3V3_HUMAN" 4 1395.6692 4.32 31602 16204 3 1395.667526 466.2303 Kinesin-like protein KIF11 OS=Homo sapiens OX=9606 GN=KIF11 PE=1 SV=2 8.41 2906.9 - 2.23E+06 - - - -1.188 - 1.72 0.354 - 189.5 1 2 0 -0.0017 13 0 0 0 1.62E+08 3.75E+07 - - - 3.9567 0.9996 221125_WJC_METTL3_EV_vs_WT_F03.16207.16207.2 1.25E-05 13/20 R.EDMTPLNLSSR[166.11].A "sp|O95785|WIZ_HUMAN,tr|A0A669KBG4|A0A669KBG4_HUMAN,tr|A0A2R8YFV2|A0A2R8YFV2_HUMAN,tr|A0A669KAV7|A0A669KAV7_HUMAN,tr|M0QXA7|M0QXA7_HUMAN,tr|A0A669KBH9|A0A669KBH9_HUMAN,tr|B9EGQ5|B9EGQ5_HUMAN" 7 1271.6055 3.57 31605 16207 2 1271.602063 636.81 Protein Wiz OS=Homo sapiens OX=9606 GN=WIZ PE=1 SV=2 4.37 2907.2 - 1.12E+06 - - - -2.7194 - 2.367 0.51 - 557.7 1 2 0 -0.0035 11 0 0 0 5.72E+07 1.60E+07 - - - 5.1377 0.9995 221125_WJC_METTL3_EV_vs_WT_F03.16208.16208.2 0.00434 18-Oct R.AATTVLQELK.K "sp|Q9NUL3|STAU2_HUMAN,tr|E5RJN7|E5RJN7_HUMAN,tr|E7EVJ4|E7EVJ4_HUMAN,tr|E7EVI1|E7EVI1_HUMAN,tr|E7EPX0|E7EPX0_HUMAN" 5 1072.6128 1.38 31606 16208 2 1072.610471 537.3137 Double-stranded RNA-binding protein Staufen homolog 2 OS=Homo sapiens OX=9606 GN=STAU2 PE=1 SV=2 6.05 2907.3 - 1.10E+06 - - - -2.1946 - 2.138 0.384 - 413.8 1 2 0 -0.0024 10 0 0 0 3.25E+07 2.35E+07 - - - 3.9975 0.9997 221125_WJC_METTL3_EV_vs_WT_F03.16214.16214.3 2.53E-05 15/36 R.MVNHFIAEFK.R "sp|P11142|HSP7C_HUMAN,tr|A8K7Q2|A8K7Q2_HUMAN,tr|E9PKE3|E9PKE3_HUMAN,tr|E9PN89|E9PN89_HUMAN" 4 1234.6169 0.14 31610 16214 3 1234.612326 412.5462 Heat shock cognate 71 kDa protein OS=Homo sapiens OX=9606 GN=HSPA8 PE=1 SV=1 6.5 2908 - 2.07E+06 - - - -3.6764 - 2.418 0.425 - 293.7 1 2 0 -0.0045 10 0 0 0 6.31E+08 4.41E+09 - - - 5.8556 0.9996 221125_WJC_METTL3_EV_vs_WT_F03.16215.16215.2 0.00934 18-Oct R.AATTVLQELK[136.11].K "sp|Q9NUL3|STAU2_HUMAN,tr|E5RJN7|E5RJN7_HUMAN,tr|E7EVJ4|E7EVJ4_HUMAN,tr|E7EVI1|E7EVI1_HUMAN,tr|E7EPX0|E7EPX0_HUMAN" 5 1080.627 1.38 31611 16215 2 1080.625457 541.3208 Double-stranded RNA-binding protein Staufen homolog 2 OS=Homo sapiens OX=9606 GN=STAU2 PE=1 SV=2 6.05 2908.1 - 1.47E+06 - - - -1.451 - 1.984 0.365 - 382.5 1 2 0 -0.0016 10 0 0 0 3.22E+07 2.33E+07 - - - 3.6488 0.9995 221125_WJC_METTL3_EV_vs_WT_F03.16218.16218.2 3.63E-06 20-Dec R.QDC[160.03]ETFGMVVK.M "sp|Q8NEY8|PPHLN_HUMAN,tr|B7Z8L1|B7Z8L1_HUMAN,tr|F8W6A0|F8W6A0_HUMAN,tr|F8W0Q9|F8W0Q9_HUMAN,tr|F8WF16|F8WF16_HUMAN" 5 1312.5792 1.42 31612 16218 2 1312.576381 657.2969 Periphilin-1 OS=Homo sapiens OX=9606 GN=PPHLN1 PE=1 SV=2 4.37 2908.5 - 1.70E+06 - - - -2.1164 - 1.601 0.489 - 442.9 1 2 0 -0.0028 11 0 0 0 4.03E+07 2.83E+07 - - - 3.925 0.9995 221125_WJC_METTL3_EV_vs_WT_F03.16219.16219.3 0.00112 13/40 R.LGLIPIHADPR[166.11].L "sp|O15160|RPAC1_HUMAN,tr|D6RDJ3|D6RDJ3_HUMAN,tr|A0A2R8YEZ4|A0A2R8YEZ4_HUMAN,tr|H0Y723|H0Y723_HUMAN,tr|E7EQB9|E7EQB9_HUMAN,tr|A0A2R8Y5D3|A0A2R8Y5D3_HUMAN,tr|A0A2R8YEY5|A0A2R8YEY5_HUMAN,tr|A0A2R8Y8D6|A0A2R8Y8D6_HUMAN" 8 1210.7062 0.29 31613 16219 3 1210.701787 404.576 DNA-directed RNA polymerases I and III subunit RPAC1 OS=Homo sapiens OX=9606 GN=POLR1C PE=1 SV=1 6.74 2908.6 - 1.29E+06 - - - -3.6136 - 1.96 0.434 - 157 1 2 0 -0.0044 11 0 0 0 1.71E+07 5.88E+07 - - - 5.2892 0.9869 221125_WJC_METTL3_EV_vs_WT_F03.16221.16221.3 8.88E-05 13/44 Y.LGEFSITYK[136.11]PVK[136.11].H "sp|P62841|RS15_HUMAN,tr|K7EM56|K7EM56_HUMAN,tr|A0A0B4J2B4|A0A0B4J2B4_HUMAN,tr|K7ELC2|K7ELC2_HUMAN,tr|K7EQJ5|K7EQJ5_HUMAN,tr|S4R417|S4R417_HUMAN" 6 1396.7937 1.36 31615 16221 3 1396.790998 466.6052 40S ribosomal protein S15 OS=Homo sapiens OX=9606 GN=RPS15 PE=1 SV=2 8.5 2908.7 - 3.28E+06 - - - -1.9366 - 2.225 0.426 - 211.6 1 1 0 -0.0027 12 0 0 0 7.45E+07 5.50E+07 - - - 5.5055 0.9945 221125_WJC_METTL3_EV_vs_WT_F03.16222.16222.2 1.78E-06 14/16 M.VNHFIAEFK[136.11].R "sp|P11142|HSP7C_HUMAN,tr|A8K7Q2|A8K7Q2_HUMAN,tr|E9PKE3|E9PKE3_HUMAN,tr|E9PN89|E9PN89_HUMAN" 4 1111.5906 0.12 31616 16222 2 1111.59018 556.8026 Heat shock cognate 71 kDa protein OS=Homo sapiens OX=9606 GN=HSPA8 PE=1 SV=1 6.72 2908.9 - 1.57E+06 - - - -0.3598 - 2.578 0.496 - 960.4 1 1 0 -0.0004 9 0 0 0 2.27E+07 1.97E+08 - - - 5.4441 0.9991 221125_WJC_METTL3_EV_vs_WT_F03.16224.16224.3 3.68E-06 18/40 K.FAAQELIEVK[136.11]R[166.11].G "sp|Q86U44|MTA70_HUMAN,tr|F5H6D8|F5H6D8_HUMAN,tr|H0YFV6|H0YFV6_HUMAN,tr|B4DTN4|B4DTN4_HUMAN" 4 1320.7521 0.06 31617 16224 3 1320.748189 441.258 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 6.14 2909.1 - 3.19E+06 - - - -2.9279 - 2.659 0.277 - 298.7 1 2 0 -0.0039 11 0 0 0 4.38E+06 7.95E+07 - - - 4.4054 1 221125_WJC_METTL3_EV_vs_WT_F03.16226.16226.2 2.16E-06 13/24 K.VIDPATATSVDLR[166.11].D sp|P50991|TCPD_HUMAN 1 1366.7332 0.2 31618 16226 2 1366.731881 684.3739 T-complex protein 1 subunit delta OS=Homo sapiens OX=9606 GN=CCT4 PE=1 SV=4 4.21 2909.3 - 2.79E+06 - - - -0.9395 - 2.696 0.583 - 532.8 1 2 0 -0.0013 13 0 0 0 1.25E+07 6.23E+07 - - - 5.892 0.9989 221125_WJC_METTL3_EV_vs_WT_F03.16227.16227.2 0.00258 16-Sep R.HYFSLGEIR.N sp|Q10472|GALT1_HUMAN 1 1120.5665 1.48 31619 16227 2 1120.56746 561.2905 Polypeptide N-acetylgalactosaminyltransferase 1 OS=Homo sapiens OX=9606 GN=GALNT1 PE=1 SV=1 6.75 2909.4 - 2.26E+06 - - - 0.8183 - 1.586 0.284 - 262.1 1 2 0 0.0009 9 0 0 0 5.18E+07 3.49E+07 - - - 2.4727 0.9999 221125_WJC_METTL3_EV_vs_WT_F03.16229.16229.2 1.14E-06 20-Nov R.QDC[160.03]ETFGMVVK[136.11].M "sp|Q8NEY8|PPHLN_HUMAN,tr|B7Z8L1|B7Z8L1_HUMAN,tr|F8W6A0|F8W6A0_HUMAN,tr|F8W0Q9|F8W0Q9_HUMAN,tr|F8WF16|F8WF16_HUMAN" 5 1320.5934 1.42 31621 16229 2 1320.592269 661.304 Periphilin-1 OS=Homo sapiens OX=9606 GN=PPHLN1 PE=1 SV=2 4.37 2909.6 - 1.91E+06 - - - -0.8254 - 2.228 0.537 - 517.9 1 2 0 -0.0011 11 0 0 0 4.03E+07 2.83E+07 - - - 5.1741 0.9447 221125_WJC_METTL3_EV_vs_WT_F03.16230.16230.3 0.0207 Nov-36 K.IKLDVPEDLR.Q "sp|Q06787|FMR1_HUMAN,tr|A0A087WY29|A0A087WY29_HUMAN,tr|R9WNI0|R9WNI0_HUMAN,tr|A8MQB8|A8MQB8_HUMAN,tr|A0A087WXI3|A0A087WXI3_HUMAN,tr|Q8IXW7|Q8IXW7_HUMAN,tr|G3V0J0|G3V0J0_HUMAN" 7 1196.6765 1.37 31622 16230 3 1196.672443 399.8994 Synaptic functional regulator FMR1 OS=Homo sapiens OX=9606 GN=FMR1 PE=1 SV=1 4.56 2909.7 - 1.32E+06 - - - -3.3802 - 2.012 0.187 - 224.1 1 2 1 -0.004 10 0 0 0 7.01E+07 5.10E+07 - - - 2.6655 0.9997 221125_WJC_METTL3_EV_vs_WT_F03.16231.16231.2 7.67E-07 24-Dec K.VIDPATATSVDLR.D sp|P50991|TCPD_HUMAN 1 1356.7249 0.31 31623 16231 2 1356.721533 679.3697 T-complex protein 1 subunit delta OS=Homo sapiens OX=9606 GN=CCT4 PE=1 SV=4 4.21 2909.8 - 1.01E+06 - - - -2.478 - 2.334 0.542 - 528.9 1 2 0 -0.0034 13 0 0 0 4.32E+07 1.40E+08 - - - 5.2185 0.9992 221125_WJC_METTL3_EV_vs_WT_F03.16232.16232.2 5.93E-05 20-Dec K.QAGVFEPTIVK.V "sp|P17987|TCPA_HUMAN,tr|F5H282|F5H282_HUMAN,tr|E7EQR6|E7EQR6_HUMAN" 3 1187.655 0.48 31624 16232 2 1187.652399 594.8348 T-complex protein 1 subunit alpha OS=Homo sapiens OX=9606 GN=TCP1 PE=1 SV=1 6 2909.9 - 850347 - - - -2.2102 - 1.738 0.394 - 249.5 1 2 0 -0.0026 11 0 0 0 2.14E+08 4.43E+08 - - - 3.4455 0.9993 221125_WJC_METTL3_EV_vs_WT_F03.16236.16236.2 0.0216 18-Oct K.IDIIPNPQER.T "sp|P08238|HS90B_HUMAN,sp|Q58FF7|H90B3_HUMAN" 2 1193.6404 0.86 31626 16236 2 1193.638952 597.8275 Heat shock protein HSP 90-beta OS=Homo sapiens OX=9606 GN=HSP90AB1 PE=1 SV=4 4.37 2910.4 - 2.18E+06 - - - -1.2441 - 1.903 0.29 - 296.3 1 2 0 -0.0015 10 0 0 0 3.03E+08 3.51E+08 - - - 2.9785 0.975 221125_WJC_METTL3_EV_vs_WT_F03.16241.16241.3 0.000536 Nov-52 L.GDVTITNDGATILK[136.11].L "sp|P17987|TCPA_HUMAN,sp|P50991|TCPD_HUMAN,tr|F5H726|F5H726_HUMAN,tr|F5H136|F5H136_HUMAN,tr|F5GZI8|F5GZI8_HUMAN,tr|E7ERF2|E7ERF2_HUMAN,tr|F5H676|F5H676_HUMAN" 7 1424.7602 0.22 31631 16241 3 1424.763239 475.9274 T-complex protein 1 subunit alpha OS=Homo sapiens OX=9606 GN=TCP1 PE=1 SV=1 4.21 2911 - 1.15E+06 - - - 2.1161 - 2.285 0.387 - 161.1 1 1 0 0.003 14 0 0 0 2.63E+06 1.21E+07 - - - 5.0499 0.9996 221125_WJC_METTL3_EV_vs_WT_F03.16243.16243.2 0.000491 18-Nov R.LTAPEDVFSK.L "sp|Q92621|NU205_HUMAN,tr|U3KPX2|U3KPX2_HUMAN" 2 1105.5655 1.84 31633 16243 2 1105.563981 553.79 Nuclear pore complex protein Nup205 OS=Homo sapiens OX=9606 GN=NUP205 PE=1 SV=3 4.37 2911.3 - 768935 - - - -1.4101 - 2.08 0.342 - 277.3 1 2 0 -0.0016 10 0 0 0 1.79E+07 9.73E+06 - - - 3.6108 0.9999 221125_WJC_METTL3_EV_vs_WT_F03.16246.16246.2 8.70E-06 13/28 K.NQVAMNPTNTVFDAK[136.11].R "sp|P11142|HSP7C_HUMAN,tr|E9PQQ4|E9PQQ4_HUMAN,tr|E9PNE6|E9PNE6_HUMAN,tr|E9PKE3|E9PKE3_HUMAN,tr|E9PLF4|E9PLF4_HUMAN,tr|E9PK54|E9PK54_HUMAN,tr|E9PN25|E9PN25_HUMAN,tr|E9PPY6|E9PPY6_HUMAN,tr|E9PQK7|E9PQK7_HUMAN" 9 1656.8021 0.07 31636 16246 2 1656.800034 829.4083 Heat shock cognate 71 kDa protein OS=Homo sapiens OX=9606 GN=HSPA8 PE=1 SV=1 5.84 2911.7 - 689948 - - - -1.2506 - 2.714 0.571 - 363.7 1 2 0 -0.0021 15 0 0 0 1.03E+06 1.39E+07 - - - 5.7124 1 221125_WJC_METTL3_EV_vs_WT_F03.16250.16250.2 1.35E-06 13/18 R.MVNHFIAEFK.R "sp|P11142|HSP7C_HUMAN,tr|A8K7Q2|A8K7Q2_HUMAN,tr|E9PKE3|E9PKE3_HUMAN,tr|E9PN89|E9PN89_HUMAN" 4 1234.6169 0.14 31638 16250 2 1234.618008 618.3157 Heat shock cognate 71 kDa protein OS=Homo sapiens OX=9606 GN=HSPA8 PE=1 SV=1 6.5 2912.1 - 5.47E+06 - - - 0.9258 - 2.743 0.531 - 806.4 1 2 0 0.0011 10 0 0 0 1.59E+08 1.14E+09 - - - 5.7792 1 221125_WJC_METTL3_EV_vs_WT_F03.16251.16251.2 4.66E-08 16/28 R.GPGLASGQLYSYPAR[166.11].R "sp|Q92785|REQU_HUMAN,tr|J3KMZ8|J3KMZ8_HUMAN,tr|E9PN04|E9PN04_HUMAN" 3 1545.7815 1.18 31639 16251 2 1545.781352 773.898 Zinc finger protein ubi-d4 OS=Homo sapiens OX=9606 GN=DPF2 PE=1 SV=2 8.59 2912.2 - 1.59E+06 - - - -0.1035 - 2.918 0.593 - 687.7 1 2 0 -0.0002 15 0 0 0 4.98E+07 4.21E+07 - - - 6.0537 0.9977 221125_WJC_METTL3_EV_vs_WT_F03.16252.16252.3 3.60E-05 14/40 R.TLKIPAMTIAK.N "sp|P10809|CH60_HUMAN,tr|A0A7I2V2X6|A0A7I2V2X6_HUMAN,tr|A0A7I2YQK6|A0A7I2YQK6_HUMAN,tr|A0A7I2V599|A0A7I2V599_HUMAN" 4 1185.7155 1.02 31640 16252 3 1185.710463 396.2458 "60 kDa heat shock protein, mitochondrial OS=Homo sapiens OX=9606 GN=HSPD1 PE=1 SV=2" 10 2912.3 - 1.92E+06 - - - -4.2616 - 2.49 0.422 - 308.7 1 2 1 -0.0051 11 0 0 0 1.82E+08 1.78E+08 - - - 5.8351 0.9997 221125_WJC_METTL3_EV_vs_WT_F03.16254.16254.2 0.00352 15/22 R.WALSQSNPSALR[166.11].E "sp|P55072|TERA_HUMAN,tr|A0A7P0Z4C6|A0A7P0Z4C6_HUMAN,tr|A0A7P0T8Q5|A0A7P0T8Q5_HUMAN,tr|C9JUP7|C9JUP7_HUMAN,tr|A0A7P0TAW3|A0A7P0TAW3_HUMAN,tr|A0A7I2V540|A0A7I2V540_HUMAN,tr|A0A7P0T8A3|A0A7P0T8A3_HUMAN,tr|A0A7P0TAQ1|A0A7P0TAQ1_HUMAN" 8 1338.692 1.04 31642 16254 2 1338.694866 670.3533 Transitional endoplasmic reticulum ATPase OS=Homo sapiens OX=9606 GN=VCP PE=1 SV=4 9.75 2912.5 - 1.56E+06 - - - 2.1641 - 2.855 0.43 - 942.1 1 2 0 0.0029 12 0 0 0 2.69E+07 2.59E+07 - - - 4.9764 0.9999 221125_WJC_METTL3_EV_vs_WT_F03.16255.16255.3 3.20E-05 14/40 R.TVVTGIEMFHK.S sp|P49411|EFTU_HUMAN 1 1260.6536 1.21 31643 16255 3 1260.651662 421.2252 "Elongation factor Tu, mitochondrial OS=Homo sapiens OX=9606 GN=TUFM PE=1 SV=2" 6.41 2912.6 - 1.23E+06 - - - -1.5722 - 2.344 0.448 - 205.5 1 2 0 -0.002 11 0 0 0 2.33E+08 1.93E+08 - - - 5.9542 0.9526 221125_WJC_METTL3_EV_vs_WT_F03.16256.16256.2 0.0349 18-Sep R.SLQVVDLESR[166.11].K "sp|Q6P4I2|WDR73_HUMAN,tr|H0YMT3|H0YMT3_HUMAN" 2 1154.6171 1.06 31644 16256 2 1155.617919 578.3158 WD repeat-containing protein 73 OS=Homo sapiens OX=9606 GN=WDR73 PE=1 SV=1 4.37 2912.6 - 1.09E+06 - - - 866.8216 - 1.769 0.367 - 217.3 1 2 0 1.0008 10 0 0 0 1.84E+07 1.74E+07 - - - 3.0296 0.9977 221125_WJC_METTL3_EV_vs_WT_F03.16260.16260.2 0.00464 16-Oct R.QLLQVIQEK.E "sp|Q9H501|ESF1_HUMAN,tr|A0A087WX71|A0A087WX71_HUMAN" 2 1097.6445 0.82 31648 16260 2 1097.64791 549.8295 ESF1 homolog OS=Homo sapiens OX=9606 GN=ESF1 PE=1 SV=1 6 2913.1 - 771519 - - - 3.144 - 2.017 0.28 - 348.7 1 2 0 0.0035 9 0 0 0 2.57E+07 3.14E+07 - - - 3.1378 0.9999 221125_WJC_METTL3_EV_vs_WT_F03.16263.16263.2 9.26E-05 22-Dec R.TNAENEFVTIKK.D sp|P04264|K2C1_HUMAN 1 1392.7249 8.55 31649 16263 2 1392.723852 697.3697 "Keratin, type II cytoskeletal 1 OS=Homo sapiens OX=9606 GN=KRT1 PE=1 SV=6" 5.81 2913.5 - 9.62E+06 - - - -0.7489 - 2.523 0.518 - 485.8 1 2 0 -0.001 12 0 0 0 2.25E+08 2.63E+07 - - - 5.3016 0.9865 221125_WJC_METTL3_EV_vs_WT_F03.16264.16264.2 0.00312 14-Oct V.NHFIAEFK[136.11].R "sp|P11142|HSP7C_HUMAN,tr|A8K7Q2|A8K7Q2_HUMAN,tr|E9PKE3|E9PKE3_HUMAN,tr|E9PN89|E9PN89_HUMAN" 4 1012.5222 0.11 31650 16264 2 1012.521173 507.2684 Heat shock cognate 71 kDa protein OS=Homo sapiens OX=9606 GN=HSPA8 PE=1 SV=1 6.75 2913.5 - 5.46E+06 - - - -0.9807 - 2.198 0.369 - 580.9 1 1 0 -0.001 8 0 0 0 1.03E+07 9.24E+07 - - - 4.1413 0.9982 221125_WJC_METTL3_EV_vs_WT_F03.16265.16265.3 1.88E-06 16/44 Y.LGEFSITYKPVK.H "sp|P62841|RS15_HUMAN,tr|K7EM56|K7EM56_HUMAN,tr|A0A0B4J2B4|A0A0B4J2B4_HUMAN,tr|K7ELC2|K7ELC2_HUMAN,tr|K7EQJ5|K7EQJ5_HUMAN,tr|S4R417|S4R417_HUMAN" 6 1380.7653 1.36 31651 16265 3 1380.763409 461.2624 40S ribosomal protein S15 OS=Homo sapiens OX=9606 GN=RPS15 PE=1 SV=2 8.5 2913.6 - 5.09E+06 - - - -1.3717 - 2.869 0.547 - 336 1 1 0 -0.0019 12 0 0 0 7.45E+07 5.50E+07 - - - 7.5594 1 221125_WJC_METTL3_EV_vs_WT_F03.16266.16266.2 6.73E-09 26-Nov R.TTPSVVAFTADGER[166.11].L "sp|P38646|GRP75_HUMAN,tr|H0Y8K0|H0Y8K0_HUMAN,tr|A0A7I2V2S7|A0A7I2V2S7_HUMAN,tr|A0A7I2V2G2|A0A7I2V2G2_HUMAN,tr|A0A3B3ITI4|A0A3B3ITI4_HUMAN,tr|A0A7I2V3F7|A0A7I2V3F7_HUMAN,tr|D6RCD7|D6RCD7_HUMAN" 7 1459.7182 0.45 31652 16266 2 1459.718725 730.8664 "Stress-70 protein, mitochondrial OS=Homo sapiens OX=9606 GN=HSPA9 PE=1 SV=2" 4.37 2913.6 - 3.72E+06 - - - 0.3302 - 2.535 0.618 - 453.6 1 2 0 0.0005 14 0 0 0 5.15E+08 1.14E+09 - - - 5.9397 0.9999 221125_WJC_METTL3_EV_vs_WT_F03.16269.16269.3 0.000603 19/52 R.IVGSK[136.11]PLYVALAQR[166.11].K "sp|Q13310|PABP4_HUMAN,tr|A0A7I2V5W9|A0A7I2V5W9_HUMAN,tr|H0YEU6|H0YEU6_HUMAN,tr|B1ANR0|B1ANR0_HUMAN,tr|A0A7I2V4L7|A0A7I2V4L7_HUMAN,tr|A0A7I2V598|A0A7I2V598_HUMAN,tr|A0A7I2V4V6|A0A7I2V4V6_HUMAN,tr|H0Y5F5|H0Y5F5_HUMAN" 8 1531.9205 1.43 31655 16269 3 1531.918077 511.6474 Polyadenylate-binding protein 4 OS=Homo sapiens OX=9606 GN=PABPC4 PE=1 SV=1 9.99 2913.8 - 2.27E+06 - - - -1.5941 - 3.019 0.373 - 419.4 1 2 0 -0.0024 14 0 0 0 3.38E+08 2.36E+08 - - - 5.6343 0.9994 221125_WJC_METTL3_EV_vs_WT_F03.16270.16270.2 0.0269 16-Sep R.QLLQVIQEK[136.11].E "sp|Q9H501|ESF1_HUMAN,tr|A0A087WX71|A0A087WX71_HUMAN" 2 1105.6587 0.82 31656 16270 2 1105.65789 553.8366 ESF1 homolog OS=Homo sapiens OX=9606 GN=ESF1 PE=1 SV=1 6 2913.9 - 1.74E+06 - - - -0.6955 - 1.81 0.303 - 263.7 1 2 0 -0.0008 9 0 0 0 2.57E+07 3.14E+07 - - - 2.9952 0.9988 221125_WJC_METTL3_EV_vs_WT_F03.16271.16271.2 1.95E-05 13/22 R.DAAAALAAMNGR.K "sp|Q01085|TIAR_HUMAN,tr|E7ETC0|E7ETC0_HUMAN,tr|A6NKZ9|A6NKZ9_HUMAN,tr|E7ETJ9|E7ETJ9_HUMAN" 4 1130.5502 0.19 31657 16271 2 1130.54533 566.2824 Nucleolysin TIAR OS=Homo sapiens OX=9606 GN=TIAL1 PE=1 SV=1 5.84 2914 - 1.60E+06 - - - -4.3448 - 2.843 0.475 - 700.3 1 2 0 -0.0049 12 0 0 0 2.53E+07 1.35E+08 - - - 5.297 0.9998 221125_WJC_METTL3_EV_vs_WT_F03.16273.16273.3 1.69E-05 14/48 K.VIDPATATSVDLR[166.11].D sp|P50991|TCPD_HUMAN 1 1366.7332 0.02 31659 16273 3 1366.731718 456.585 T-complex protein 1 subunit delta OS=Homo sapiens OX=9606 GN=CCT4 PE=1 SV=4 4.21 2914.2 - 770003 - - - -1.0587 - 2.427 0.332 - 217.7 1 2 0 -0.0014 13 0 0 0 1.85E+05 1.13E+07 - - - 4.6451 0.9997 221125_WJC_METTL3_EV_vs_WT_F03.16274.16274.3 0.0941 15/48 K.HLAGLGLTEAIDK[136.11].N "sp|P50454|SERPH_HUMAN,tr|E9PKH2|E9PKH2_HUMAN,tr|E9PJH8|E9PJH8_HUMAN" 3 1344.7493 1.31 31660 16274 3 1344.746712 449.257 Serpin H1 OS=Homo sapiens OX=9606 GN=SERPINH1 PE=1 SV=2 5.32 2914.4 - 767756 - - - -1.8985 - 2.455 0.325 - 348.9 1 2 0 -0.0026 13 0 0 0 9.79E+07 7.50E+07 - - - 4.5978 0.9935 221125_WJC_METTL3_EV_vs_WT_F03.16276.16276.2 4.15E-05 13/24 Y.VVESTGVFTTMEK[136.11].A "sp|P04406|G3P_HUMAN,tr|E7EUT5|E7EUT5_HUMAN" 2 1434.7156 0.79 31662 16276 2 1434.71433 718.3651 Glyceraldehyde-3-phosphate dehydrogenase OS=Homo sapiens OX=9606 GN=GAPDH PE=1 SV=3 4.53 2914.6 - 538325 - - - -0.8726 - 2.598 0.52 - 408.2 1 1 0 -0.0013 13 0 0 0 3.47E+06 4.40E+06 - - - 5.3317 0.9983 221125_WJC_METTL3_EV_vs_WT_F03.16277.16277.3 0.00537 Oct-56 R.VLPSPAR[166.11]PFPASLGR[166.11].A sp|P48634|PRC2A_HUMAN 1 1583.9051 1.93 31663 16277 3 1583.902471 528.9756 Protein PRRC2A OS=Homo sapiens OX=9606 GN=PRRC2A PE=1 SV=3 12 2914.8 - 528472 - - - -1.651 - 1.897 0.267 - 114 1 2 0 -0.0026 15 0 0 0 6.11E+07 3.17E+07 - - - 3.1868 0.9999 221125_WJC_METTL3_EV_vs_WT_F03.16281.16281.2 2.54E-08 26-Oct R.TTPSVVAFTADGER.L "sp|P38646|GRP75_HUMAN,tr|H0Y8K0|H0Y8K0_HUMAN,tr|A0A7I2V2S7|A0A7I2V2S7_HUMAN,tr|A0A7I2V2G2|A0A7I2V2G2_HUMAN,tr|A0A3B3ITI4|A0A3B3ITI4_HUMAN,tr|A0A7I2V3F7|A0A7I2V3F7_HUMAN,tr|D6RCD7|D6RCD7_HUMAN" 7 1449.71 0.45 31665 16281 2 1449.709556 725.8623 "Stress-70 protein, mitochondrial OS=Homo sapiens OX=9606 GN=HSPA9 PE=1 SV=2" 4.37 2915.2 - 4.34E+06 - - - -0.2876 - 2.24 0.573 - 276.7 1 2 0 -0.0004 14 0 0 0 5.15E+08 1.14E+09 - - - 5.2969 0.9958 221125_WJC_METTL3_EV_vs_WT_F03.16283.16283.3 0.00377 Oct-36 K.IK[136.11]LDVPEDLR[166.11].Q "sp|Q06787|FMR1_HUMAN,tr|A0A087WY29|A0A087WY29_HUMAN,tr|R9WNI0|R9WNI0_HUMAN,tr|A8MQB8|A8MQB8_HUMAN,tr|A0A087WXI3|A0A087WXI3_HUMAN,tr|Q8IXW7|Q8IXW7_HUMAN,tr|G3V0J0|G3V0J0_HUMAN" 7 1214.699 1.39 31667 16283 3 1214.698899 405.9069 Synaptic functional regulator FMR1 OS=Homo sapiens OX=9606 GN=FMR1 PE=1 SV=1 4.56 2915.3 - 3.60E+06 - - - -0.0486 - 1.863 0.271 - 156.4 1 2 1 -0.0001 10 0 0 0 7.01E+07 5.05E+07 - - - 3.3784 0.9998 221125_WJC_METTL3_EV_vs_WT_F03.16286.16286.2 2.81E-06 22-Dec K.LVC[160.03]TDIADVSVK.Q "sp|O43148|MCES_HUMAN,tr|K7EP06|K7EP06_HUMAN" 2 1318.6803 0.83 31670 16286 2 1318.678376 660.3474 mRNA cap guanine-N7 methyltransferase OS=Homo sapiens OX=9606 GN=RNMT PE=1 SV=1 4.21 2915.5 - 1.77E+06 - - - -1.4234 - 2.155 0.517 - 469 1 2 0 -0.0019 12 0 0 0 1.13E+07 1.36E+07 - - - 4.8792 1 221125_WJC_METTL3_EV_vs_WT_F03.16287.16287.3 2.66E-06 13/52 R.TTPSVVAFTADGER[166.11].L "sp|P38646|GRP75_HUMAN,tr|H0Y8K0|H0Y8K0_HUMAN,tr|A0A7I2V2S7|A0A7I2V2S7_HUMAN,tr|A0A7I2V2G2|A0A7I2V2G2_HUMAN,tr|A0A3B3ITI4|A0A3B3ITI4_HUMAN,tr|A0A7I2V3F7|A0A7I2V3F7_HUMAN,tr|D6RCD7|D6RCD7_HUMAN" 7 1459.7182 0.55 31671 16287 3 1459.718374 487.58 "Stress-70 protein, mitochondrial OS=Homo sapiens OX=9606 GN=HSPA9 PE=1 SV=2" 4.37 2915.6 - 1.50E+06 - - - 0.0897 - 2.384 0.518 - 140 1 2 0 0.0001 14 0 0 0 6.35E+07 1.16E+08 - - - 6.624 0.9971 221125_WJC_METTL3_EV_vs_WT_F03.16289.16289.2 0.00102 18-Oct K.NLPNVIINEK[136.11].R sp|Q9BVJ6|UT14A_HUMAN 1 1160.6645 2 31673 16289 2 1160.661785 581.3395 U3 small nucleolar RNA-associated protein 14 homolog A OS=Homo sapiens OX=9606 GN=UTP14A PE=1 SV=1 6 2915.8 - 1.23E+06 - - - -2.3159 - 1.798 0.22 - 258.5 1 2 0 -0.0027 10 0 0 0 5.04E+07 2.52E+07 - - - 2.3027 0.9999 221125_WJC_METTL3_EV_vs_WT_F03.16290.16290.3 3.15E-05 14/48 K.ALMGLYHGQVLC[160.03]K.K "sp|P40939|ECHA_HUMAN,tr|A0A2R8YG21|A0A2R8YG21_HUMAN,tr|H0YFD6|H0YFD6_HUMAN,tr|A0A2R8Y4F5|A0A2R8Y4F5_HUMAN" 4 1488.7581 0.72 31674 16290 3 1488.758083 497.26 "Trifunctional enzyme subunit alpha, mitochondrial OS=Homo sapiens OX=9606 GN=HADHA PE=1 SV=2" 8.25 2915.9 - 1.07E+06 - - - -0.0289 - 2.351 0.416 - 229.8 1 2 0 0 13 0 0 0 9.53E+06 1.33E+07 - - - 5.4957 0.9984 221125_WJC_METTL3_EV_vs_WT_F03.16293.16293.2 0.0015 20-Nov K.NILSSADYVER[166.11].G sp|Q12846|STX4_HUMAN 1 1275.6335 3.59 31677 16293 2 1275.637047 638.824 Syntaxin-4 OS=Homo sapiens OX=9606 GN=STX4 PE=1 SV=2 4.37 2916.2 - 816586 - - - 2.819 - 1.772 0.36 - 352.5 1 2 0 0.0036 11 0 0 0 3.28E+07 9.14E+06 - - - 3.2465 0.9976 221125_WJC_METTL3_EV_vs_WT_F03.16296.16296.3 0.00344 Aug-36 R.ALKDEIDVLR.A sp|Q9UJC3|HOOK1_HUMAN 1 1170.6608 1.46 31680 16296 3 1170.657794 391.2276 Protein Hook homolog 1 OS=Homo sapiens OX=9606 GN=HOOK1 PE=1 SV=2 4.56 2916.6 - 512162 - - - -2.6002 - 1.982 0.365 - 77.7 1 2 1 -0.003 10 0 0 0 3.56E+06 2.43E+06 - - - 4.6064 0.9999 221125_WJC_METTL3_EV_vs_WT_F03.16299.16299.3 0.0516 15/40 R.TVVTGIEMFHK[136.11].S sp|P49411|EFTU_HUMAN 1 1268.6678 1.21 31682 16299 3 1268.664931 423.8966 "Elongation factor Tu, mitochondrial OS=Homo sapiens OX=9606 GN=TUFM PE=1 SV=2" 6.41 2917 - 1.25E+07 - - - -2.2961 - 2.584 0.45 - 242.6 1 2 0 -0.0029 11 0 0 0 2.34E+08 1.94E+08 - - - 6.2532 1 221125_WJC_METTL3_EV_vs_WT_F03.16301.16301.3 4.85E-06 13/52 R.IVGSKPLYVALAQR.K "sp|Q13310|PABP4_HUMAN,tr|A0A7I2V5W9|A0A7I2V5W9_HUMAN,tr|H0YEU6|H0YEU6_HUMAN,tr|B1ANR0|B1ANR0_HUMAN,tr|A0A7I2V4L7|A0A7I2V4L7_HUMAN,tr|A0A7I2V598|A0A7I2V598_HUMAN,tr|A0A7I2V4V6|A0A7I2V4V6_HUMAN,tr|H0Y5F5|H0Y5F5_HUMAN" 8 1513.898 1.43 31683 16301 3 1513.896831 505.64 Polyadenylate-binding protein 4 OS=Homo sapiens OX=9606 GN=PABPC4 PE=1 SV=1 9.99 2917.2 - 9.01E+06 - - - -0.8045 - 2.42 0.464 - 228.6 1 2 0 -0.0012 14 0 0 0 3.38E+08 2.36E+08 - - - 6.0614 0.9999 221125_WJC_METTL3_EV_vs_WT_F03.16302.16302.3 0.000243 15/40 R.TLK[136.11]IPAMTIAK[136.11].N "sp|P10809|CH60_HUMAN,tr|A0A7I2V2X6|A0A7I2V2X6_HUMAN,tr|A0A7I2YQK6|A0A7I2YQK6_HUMAN,tr|A0A7I2V599|A0A7I2V599_HUMAN" 4 1201.7439 1.04 31684 16302 3 1201.742692 401.5886 "60 kDa heat shock protein, mitochondrial OS=Homo sapiens OX=9606 GN=HSPD1 PE=1 SV=2" 10 2917.2 - 5.00E+06 - - - -1.0185 - 2.473 0.48 - 323.1 1 2 1 -0.0012 11 0 0 0 2.28E+08 2.18E+08 - - - 6.4634 0.9997 221125_WJC_METTL3_EV_vs_WT_F03.16303.16303.2 0.00769 18-Oct K.NLPNVIINEK.R sp|Q9BVJ6|UT14A_HUMAN 1 1152.6503 2 31685 16303 2 1152.649689 577.3324 U3 small nucleolar RNA-associated protein 14 homolog A OS=Homo sapiens OX=9606 GN=UTP14A PE=1 SV=1 6 2917.3 - 4.07E+06 - - - -0.5067 - 1.837 0.406 - 282.8 1 2 0 -0.0006 10 0 0 0 5.04E+07 2.52E+07 - - - 3.737 0.9997 221125_WJC_METTL3_EV_vs_WT_F03.16305.16305.2 0.00395 16-Jul K.SDVETIFSK[136.11].Y "sp|Q9UKM9|RALY_HUMAN,tr|Q5QPM2|Q5QPM2_HUMAN,tr|Q5QPM1|Q5QPM1_HUMAN,tr|Q5QPL9|Q5QPL9_HUMAN" 4 1032.5219 1.11 31687 16305 2 1032.521144 517.2682 RNA-binding protein Raly OS=Homo sapiens OX=9606 GN=RALY PE=1 SV=1 4.37 2917.4 - 1.50E+06 - - - -0.7235 - 1.708 0.402 - 167.8 1 2 0 -0.0007 9 0 0 0 2.93E+07 2.63E+07 - - - 3.5587 0.9998 221125_WJC_METTL3_EV_vs_WT_F03.16306.16306.2 2.35E-06 18/24 K.YPASTVQILGAEK.A "sp|O00567|NOP56_HUMAN,tr|A0A494C128|A0A494C128_HUMAN,tr|H0YDU4|H0YDU4_HUMAN,tr|H0Y653|H0Y653_HUMAN" 4 1375.7347 0.82 31688 16306 2 1375.737389 688.8746 Nucleolar protein 56 OS=Homo sapiens OX=9606 GN=NOP56 PE=1 SV=4 6 2917.6 - 1.49E+06 - - - 1.9321 - 3.102 0.456 - 1219.8 1 2 0 0.0027 13 0 0 0 2.41E+07 2.94E+07 - - - 5.3136 0.998 221125_WJC_METTL3_EV_vs_WT_F03.16307.16307.3 0.00886 Nov-56 R.VLPSPARPFPASLGR.A sp|P48634|PRC2A_HUMAN 1 1563.8885 1.86 31689 16307 3 1563.890619 522.3035 Protein PRRC2A OS=Homo sapiens OX=9606 GN=PRRC2A PE=1 SV=3 12 2917.6 - 1.47E+06 - - - 1.3255 - 1.88 0.254 - 136.5 1 2 0 0.0021 15 0 0 0 7.68E+07 4.13E+07 - - - 3.0185 0.9998 221125_WJC_METTL3_EV_vs_WT_F03.16308.16308.3 0.000114 Dec-52 R.TTPSVVAFTADGER.L "sp|P38646|GRP75_HUMAN,tr|H0Y8K0|H0Y8K0_HUMAN,tr|A0A7I2V2S7|A0A7I2V2S7_HUMAN,tr|A0A7I2V2G2|A0A7I2V2G2_HUMAN,tr|A0A3B3ITI4|A0A3B3ITI4_HUMAN,tr|A0A7I2V3F7|A0A7I2V3F7_HUMAN,tr|D6RCD7|D6RCD7_HUMAN" 7 1449.71 0.55 31690 16308 3 1449.708419 484.2439 "Stress-70 protein, mitochondrial OS=Homo sapiens OX=9606 GN=HSPA9 PE=1 SV=2" 4.37 2917.7 - 1.36E+06 - - - -1.0719 - 2.115 0.381 - 111.5 1 2 0 -0.0016 14 0 0 0 6.40E+07 1.17E+08 - - - 4.778 0.9972 221125_WJC_METTL3_EV_vs_WT_F03.16309.16309.3 0.0477 Nov-48 K.ALMGLYHGQVLC[160.03]K[136.11].K "sp|P40939|ECHA_HUMAN,tr|A0A2R8YG21|A0A2R8YG21_HUMAN,tr|H0YFD6|H0YFD6_HUMAN,tr|A0A2R8Y4F5|A0A2R8Y4F5_HUMAN" 4 1496.7723 0.71 31691 16309 3 1496.771973 499.9314 "Trifunctional enzyme subunit alpha, mitochondrial OS=Homo sapiens OX=9606 GN=HADHA PE=1 SV=2" 8.25 2917.8 - 1.31E+06 - - - -0.2358 - 2.016 0.195 - 139.8 1 2 0 -0.0004 13 0 0 0 9.53E+06 1.34E+07 - - - 2.6149 0.9998 221125_WJC_METTL3_EV_vs_WT_F03.16312.16312.2 8.45E-06 18-Sep R.DVFYYSPSGK[136.11].K sp|O95983|MBD3_HUMAN 1 1169.5484 1.55 31694 16312 2 1169.549617 585.7815 Methyl-CpG-binding domain protein 3 OS=Homo sapiens OX=9606 GN=MBD3 PE=1 SV=1 5.83 2918.1 - 537758 - - - 1.0064 - 1.87 0.475 - 277.2 1 2 0 0.0012 10 0 0 0 2.34E+07 1.50E+07 - - - 4.2962 0.9736 221125_WJC_METTL3_EV_vs_WT_F03.16313.16313.2 0.0116 20-Nov R.TLKIPAMTIAK.N "sp|P10809|CH60_HUMAN,tr|A0A7I2V2X6|A0A7I2V2X6_HUMAN,tr|A0A7I2YQK6|A0A7I2YQK6_HUMAN,tr|A0A7I2V599|A0A7I2V599_HUMAN" 4 1185.7155 1.3 31695 16313 2 1185.719638 593.865 "60 kDa heat shock protein, mitochondrial OS=Homo sapiens OX=9606 GN=HSPD1 PE=1 SV=2" 10 2918.2 - 387205 - - - 3.4764 - 1.793 0.367 - 257.6 1 2 1 0.0041 11 0 0 0 2.30E+07 1.77E+07 - - - 3.3299 0.9998 221125_WJC_METTL3_EV_vs_WT_F03.16315.16315.2 7.96E-05 16-Aug K.YEWDVAEAR[166.11].K sp|P13639|EF2_HUMAN 1 1147.5174 0.53 31696 16315 2 1147.516168 574.766 Elongation factor 2 OS=Homo sapiens OX=9606 GN=EEF2 PE=1 SV=4 4.14 2918.4 - 2.90E+06 - - - -1.037 - 1.745 0.479 - 265.2 1 2 0 -0.0012 9 0 0 0 2.75E+07 5.22E+07 - - - 4.1892 0.9998 221125_WJC_METTL3_EV_vs_WT_F03.16318.16318.2 8.86E-05 20-Aug K.LVTDEDVFPTK.Y "sp|Q70IA6|MOB2_HUMAN,tr|A0A087WVS8|A0A087WVS8_HUMAN" 2 1262.6394 2.39 31698 16318 2 1262.63763 632.327 MOB kinase activator 2 OS=Homo sapiens OX=9606 GN=MOB2 PE=1 SV=1 4.03 2918.7 - 2.89E+06 - - - -1.4288 - 1.858 0.508 - 183.5 1 2 0 -0.0018 11 0 0 0 4.52E+07 1.89E+07 - - - 4.4684 1 221125_WJC_METTL3_EV_vs_WT_F03.16320.16320.2 1.16E-05 16/24 K.YPASTVQILGAEK[136.11].A "sp|O00567|NOP56_HUMAN,tr|A0A494C128|A0A494C128_HUMAN,tr|H0YDU4|H0YDU4_HUMAN,tr|H0Y653|H0Y653_HUMAN" 4 1383.7489 0.82 31700 16320 2 1383.747078 692.8817 Nucleolar protein 56 OS=Homo sapiens OX=9606 GN=NOP56 PE=1 SV=4 6 2918.9 - 1.59E+06 - - - -1.3391 - 3.319 0.549 - 772.8 1 2 0 -0.0019 13 0 0 0 2.41E+07 2.94E+07 - - - 6.1743 1 221125_WJC_METTL3_EV_vs_WT_F03.16322.16322.2 1.07E-09 15/26 R.IVGSKPLYVALAQR.K "sp|Q13310|PABP4_HUMAN,tr|A0A7I2V5W9|A0A7I2V5W9_HUMAN,tr|H0YEU6|H0YEU6_HUMAN,tr|B1ANR0|B1ANR0_HUMAN,tr|A0A7I2V4L7|A0A7I2V4L7_HUMAN,tr|A0A7I2V598|A0A7I2V598_HUMAN,tr|A0A7I2V4V6|A0A7I2V4V6_HUMAN,tr|H0Y5F5|H0Y5F5_HUMAN" 8 1513.898 1.47 31702 16322 2 1513.895283 757.9563 Polyadenylate-binding protein 4 OS=Homo sapiens OX=9606 GN=PABPC4 PE=1 SV=1 9.99 2919.2 - 925360 - - - -1.8271 - 2.714 0.627 - 499.1 1 2 0 -0.0028 14 0 0 0 2.22E+07 1.52E+07 - - - 6.1766 0.9981 221125_WJC_METTL3_EV_vs_WT_F03.16323.16323.2 0.0138 13/16 K.HDVVFLITK[136.11].Y "sp|Q00610|CLH1_HUMAN,tr|A0A087WVQ6|A0A087WVQ6_HUMAN" 2 1078.6266 0.84 31703 16323 2 1078.621625 540.3206 Clathrin heavy chain 1 OS=Homo sapiens OX=9606 GN=CLTC PE=1 SV=5 6.74 2919.3 - 800800 - - - -4.6411 - 2.512 0.415 - 510.1 1 2 0 -0.005 9 0 0 0 5.37E+07 6.39E+07 - - - 4.7693 0.9992 221125_WJC_METTL3_EV_vs_WT_F03.16324.16324.3 0.0101 Oct-36 R.KLDELYGTWR.K "sp|P36578|RL4_HUMAN,tr|H3BM89|H3BM89_HUMAN" 2 1279.6561 0.81 31704 16324 3 1279.654877 427.5593 60S ribosomal protein L4 OS=Homo sapiens OX=9606 GN=RPL4 PE=1 SV=5 6.07 2919.4 - 789672 - - - -0.9456 - 1.969 0.267 - 133.2 1 2 0 -0.0012 10 0 0 0 8.21E+06 1.01E+07 - - - 3.4951 0.7832 221125_WJC_METTL3_EV_vs_WT_F03.16325.16325.2 1.03 16-Sep V.VTGIEMFHK.S sp|P49411|EFTU_HUMAN 1 1060.5376 0.67 31705 16325 2 1060.535333 531.2761 "Elongation factor Tu, mitochondrial OS=Homo sapiens OX=9606 GN=TUFM PE=1 SV=2" 6.72 2919.6 - 811693 - - - -2.0923 - 1.418 0.236 - 211.6 1 1 0 -0.0022 9 0 0 0 7.77E+06 1.16E+07 - - - 1.7938 1 221125_WJC_METTL3_EV_vs_WT_F03.16326.16326.2 3.91E-12 16/30 K.LLTSQC[160.03]GAAEEEFVQR[166.11].F sp|P82933|RT09_HUMAN 1 1846.8759 1.27 31706 16326 2 1846.871361 924.4452 "28S ribosomal protein S9, mitochondrial OS=Homo sapiens OX=9606 GN=MRPS9 PE=1 SV=2" 4.25 2919.7 - 488198 - - - -2.4485 - 3.464 0.698 - 1158.4 1 2 0 -0.0045 16 0 0 0 6.40E+06 5.05E+06 - - - 7.2496 0.9988 221125_WJC_METTL3_EV_vs_WT_F03.16327.16327.2 0.00411 20-Nov R.QYLEELQSVQR[166.11].E "sp|Q6WCQ1|MPRIP_HUMAN,tr|A0A494BZV2|A0A494BZV2_HUMAN,tr|H7C3G6|H7C3G6_HUMAN,tr|H0Y7E2|H0Y7E2_HUMAN,tr|H0Y2S9|H0Y2S9_HUMAN,tr|J3KSW8|J3KSW8_HUMAN" 6 1401.7128 0.13 31707 16327 2 1401.711039 701.8637 Myosin phosphatase Rho-interacting protein OS=Homo sapiens OX=9606 GN=MPRIP PE=1 SV=3 4.53 2919.8 - 457493 - - - -1.2306 - 1.877 0.231 - 293.6 1 2 0 -0.0017 11 0 0 0 1.92E+06 1.51E+07 - - - 2.45 1 221125_WJC_METTL3_EV_vs_WT_F03.16328.16328.2 1.09E-11 17/30 R.VADFTEQYNEQYGAVR.T sp|Q9BQ04|RBM4B_HUMAN 1 1888.8592 1.58 31708 16328 2 1888.858435 945.4369 RNA-binding protein 4B OS=Homo sapiens OX=9606 GN=RBM4B PE=1 SV=1 4.14 2920 - 256580 - - - -0.3817 - 3.595 0.697 - 1274.8 1 2 0 -0.0007 16 0 0 0 2.87E+07 1.81E+07 - - - 7.3346 0.9972 221125_WJC_METTL3_EV_vs_WT_F03.16330.16330.2 0.126 18-Jun R.SMQDVVEDFK.N sp|P08729|K2C7_HUMAN 1 1196.5383 999 31709 16330 2 1196.537345 599.2764 "Keratin, type II cytoskeletal 7 OS=Homo sapiens OX=9606 GN=KRT7 PE=1 SV=5" 4.03 2920.2 - 3.66E+07 - - - -0.8307 - 1.199 0.281 - 114.1 1 2 0 -0.001 10 0 0 0 5.12E+08 0.00E+00 - - - 1.6227 0.9642 221125_WJC_METTL3_EV_vs_WT_F03.16332.16332.2 0.0281 16-Sep C.AVEFNFGQK.E "sp|Q00839|HNRPU_HUMAN,tr|A0A1W2PQL0|A0A1W2PQL0_HUMAN,tr|A0A1W2PPL4|A0A1W2PPL4_HUMAN,tr|A0A1W2PQ74|A0A1W2PQ74_HUMAN,tr|Q5RI18|Q5RI18_HUMAN,tr|A0A1W2PP35|A0A1W2PP35_HUMAN,tr|A0A1W2PPS1|A0A1W2PPS1_HUMAN,tr|A0A1W2PRZ7|A0A1W2PRZ7_HUMAN,tr|A0A1W2PPH7|A0A1W2PPH7_HUMAN,tr|A0A1W2PP34|A0A1W2PP34_HUMAN,tr|A0A1X7SBS1|A0A1X7SBS1_HUMAN" 11 1038.5134 1 31710 16332 2 1038.512739 520.264 Heterogeneous nuclear ribonucleoprotein U OS=Homo sapiens OX=9606 GN=HNRNPU PE=1 SV=6 6.05 2920.4 - 3.22E+06 - - - -0.6798 - 1.649 0.324 - 240.4 1 1 0 -0.0007 9 0 0 0 6.76E+07 6.77E+07 - - - 2.8809 0.9821 221125_WJC_METTL3_EV_vs_WT_F03.16333.16333.2 0.0229 20-Jun R.YNPENLATLER[166.11].Y "sp|Q9UBQ5|EIF3K_HUMAN,tr|K7ERF1|K7ERF1_HUMAN,tr|K7ES31|K7ES31_HUMAN" 3 1328.66 1.22 31711 16333 2 1328.655108 665.3373 Eukaryotic translation initiation factor 3 subunit K OS=Homo sapiens OX=9606 GN=EIF3K PE=1 SV=1 4.53 2920.4 - 3.15E+06 - - - -3.6819 - 1.305 0.253 - 93.4 1 2 0 -0.0049 11 0 0 0 5.35E+07 4.38E+07 - - - 1.6283 0.9998 221125_WJC_METTL3_EV_vs_WT_F03.16334.16334.2 6.31E-05 13/24 R.AAVSAFPTDSLER[166.11].D "sp|O14654|IRS4_HUMAN,tr|A0A804CF45|A0A804CF45_HUMAN" 2 1372.6862 1.11 31712 16334 2 1372.686992 687.3504 Insulin receptor substrate 4 OS=Homo sapiens OX=9606 GN=IRS4 PE=1 SV=1 4.37 2920.5 - 2.28E+06 - - - 0.566 - 2.545 0.366 - 432.8 1 2 0 0.0008 13 0 0 0 2.84E+08 2.56E+08 - - - 4.1415 1 221125_WJC_METTL3_EV_vs_WT_F03.16335.16335.2 3.93E-09 15/26 R.VAVEYLDPSPEVQK.K "sp|O43684|BUB3_HUMAN,tr|J3QT28|J3QT28_HUMAN" 2 1572.8035 0.74 31713 16335 2 1572.80123 787.409 Mitotic checkpoint protein BUB3 OS=Homo sapiens OX=9606 GN=BUB3 PE=1 SV=1 4.14 2920.6 - 2.05E+06 - - - -1.4681 - 2.698 0.586 - 726.4 1 2 0 -0.0023 14 0 0 0 4.19E+07 5.67E+07 - - - 5.8591 0.9999 221125_WJC_METTL3_EV_vs_WT_F03.16336.16336.2 0.0342 13/16 K.HDVVFLITK.Y "sp|Q00610|CLH1_HUMAN,tr|A0A087WVQ6|A0A087WVQ6_HUMAN" 2 1070.6124 0.84 31714 16336 2 1070.611189 536.3135 Clathrin heavy chain 1 OS=Homo sapiens OX=9606 GN=CLTC PE=1 SV=5 6.74 2920.7 - 1.80E+06 - - - -1.1601 - 2.64 0.513 - 701.9 1 2 0 -0.0012 9 0 0 0 5.37E+07 6.39E+07 - - - 5.6381 0.9996 221125_WJC_METTL3_EV_vs_WT_F03.16337.16337.3 0.0083 Dec-40 K.STIGAYFLKPK.E "sp|Q8NI36|WDR36_HUMAN,tr|A0A0A0MTB8|A0A0A0MTB8_HUMAN" 2 1223.6914 0.4 31715 16337 3 1223.688626 408.9044 WD repeat-containing protein 36 OS=Homo sapiens OX=9606 GN=WDR36 PE=1 SV=1 9.7 2920.8 - 1.23E+06 - - - -2.2751 - 2.226 0.349 - 146.9 1 2 0 -0.0028 11 0 0 0 9.32E+06 2.35E+07 - - - 4.7035 0.7754 221125_WJC_METTL3_EV_vs_WT_F03.16338.16338.2 0.031 30-Oct L.R[166.11]GGGAGGC[160.03]GGPGGGGR[166.11].L sp|Q7RTS3|PTF1A_HUMAN 1 1305.586 0.11 31716 16338 2 1305.5839 653.8003 Pancreas transcription factor 1 subunit alpha OS=Homo sapiens OX=9606 GN=PTF1A PE=1 SV=1 10.35 2920.9 - 1.03E+06 - - - -1.5732 - 1.406 0.218 - 197 1 1 0 -0.0021 16 0 0 0 2.25E+06 1.96E+07 - - - 1.4882 0.9999 221125_WJC_METTL3_EV_vs_WT_F03.16339.16339.2 1.36E-07 14/26 R.IVGSK[136.11]PLYVALAQR[166.11].K "sp|Q13310|PABP4_HUMAN,tr|A0A7I2V5W9|A0A7I2V5W9_HUMAN,tr|H0YEU6|H0YEU6_HUMAN,tr|B1ANR0|B1ANR0_HUMAN,tr|A0A7I2V4L7|A0A7I2V4L7_HUMAN,tr|A0A7I2V598|A0A7I2V598_HUMAN,tr|A0A7I2V4V6|A0A7I2V4V6_HUMAN,tr|H0Y5F5|H0Y5F5_HUMAN" 8 1531.9205 1.47 31717 16339 2 1531.919709 766.9675 Polyadenylate-binding protein 4 OS=Homo sapiens OX=9606 GN=PABPC4 PE=1 SV=1 9.99 2921.1 - 1.01E+06 - - - -0.5287 - 2.615 0.574 - 430.8 1 2 0 -0.0008 14 0 0 0 2.22E+07 1.52E+07 - - - 5.6926 0.9998 221125_WJC_METTL3_EV_vs_WT_F03.16340.16340.3 0.000288 13/44 K.YPFILPHQQVDK[136.11].G "sp|Q9ULC4|MCTS1_HUMAN,tr|A0A3B3IRV3|A0A3B3IRV3_HUMAN" 2 1491.7966 0.35 31718 16340 3 1491.799254 498.2728 Malignant T-cell-amplified sequence 1 OS=Homo sapiens OX=9606 GN=MCTS1 PE=1 SV=1 6.74 2921.2 - 959793 - - - 1.8126 - 2.318 0.365 - 171.2 1 2 0 0.0027 12 0 0 0 7.95E+06 2.28E+07 - - - 4.9389 1 221125_WJC_METTL3_EV_vs_WT_F03.16341.16341.3 2.42E-08 15/48 R.LLVGNDDVHIIAR.S sp|Q7Z6Z7|HUWE1_HUMAN 1 1433.7991 0.86 31719 16341 3 1433.796979 478.9403 E3 ubiquitin-protein ligase HUWE1 OS=Homo sapiens OX=9606 GN=HUWE1 PE=1 SV=3 5.21 2921.3 - 831619 - - - -1.4535 - 3.145 0.538 - 346 1 2 0 -0.0021 13 0 0 0 2.95E+07 3.43E+07 - - - 7.6442 0.9523 221125_WJC_METTL3_EV_vs_WT_F03.16342.16342.3 0.00074 Dec-48 K.AGHYLELGAEIAR.T "sp|O60476|MA1A2_HUMAN,tr|H0Y7H1|H0Y7H1_HUMAN,tr|H0Y543|H0Y543_HUMAN" 3 1398.7256 1 31720 16342 3 1398.725547 467.2491 "Mannosyl-oligosaccharide 1,2-alpha-mannosidase IB OS=Homo sapiens OX=9606 GN=MAN1A2 PE=1 SV=1" 5.4 2921.5 - 798916 - - - -0.0114 - 2.498 0 - 211.3 2 2 0 0 13 0 0 0 1.61E+07 1.61E+07 - - - 0.8828 1 221125_WJC_METTL3_EV_vs_WT_F03.16344.16344.2 8.13E-11 14/30 K.LLTSQC[160.03]GAAEEEFVQR.F sp|P82933|RT09_HUMAN 1 1836.8676 1.27 31722 16344 2 1836.864472 919.4411 "28S ribosomal protein S9, mitochondrial OS=Homo sapiens OX=9606 GN=MRPS9 PE=1 SV=2" 4.25 2921.7 - 601846 - - - -1.71 - 3.138 0.67 - 715.4 1 2 0 -0.0031 16 0 0 0 6.40E+06 5.05E+06 - - - 6.8002 0.9981 221125_WJC_METTL3_EV_vs_WT_F03.16345.16345.3 0.0112 Nov-40 R.R[166.11]LTPLQLEIQR[166.11].V "sp|Q8N163|CCAR2_HUMAN,tr|H0YB24|H0YB24_HUMAN,tr|G3V119|G3V119_HUMAN" 3 1385.8258 1.11 31723 16345 3 1385.822165 462.9492 Cell cycle and apoptosis regulator protein 2 OS=Homo sapiens OX=9606 GN=CCAR2 PE=1 SV=2 9.6 2921.8 - 418698 - - - -2.6035 - 2.151 0.258 - 191.5 1 2 0 -0.0036 11 0 0 0 5.82E+06 5.26E+06 - - - 3.5913 0.9999 221125_WJC_METTL3_EV_vs_WT_F03.16348.16348.2 2.43E-08 28-Sep K.GFGYGQGAGALVHAQ.- "sp|Q16527|CSRP2_HUMAN,tr|F8VW96|F8VW96_HUMAN" 2 1431.6895 - 31725 16348 2 1431.689684 716.852 Cysteine and glycine-rich protein 2 OS=Homo sapiens OX=9606 GN=CSRP2 PE=1 SV=3 6.74 2922.2 - 3.77E+06 - - - 0.1201 - 2.155 0.621 - 221.3 1 2 0 0.0002 15 0 0 0 - - - - - 5.5153 0.9997 221125_WJC_METTL3_EV_vs_WT_F03.16350.16350.2 0.00384 18-Nov K.LAELEEALQK.A "sp|P13647|K2C5_HUMAN,tr|H0YI76|H0YI76_HUMAN" 2 1142.6183 33.06 31726 16350 2 1142.617547 572.3164 "Keratin, type II cytoskeletal 5 OS=Homo sapiens OX=9606 GN=KRT5 PE=1 SV=3" 4.25 2922.4 - 3.04E+07 - - - -0.6625 - 2.481 0.307 - 453.8 1 2 0 -0.0008 10 0 0 0 5.12E+08 1.55E+07 - - - 3.8446 0.9985 221125_WJC_METTL3_EV_vs_WT_F03.16351.16351.2 0.0157 18-Nov K.QQLLIGAYAK[136.11].A sp|Q99832|TCPH_HUMAN 1 1111.6481 0.14 31727 16351 2 1111.644727 556.8313 T-complex protein 1 subunit eta OS=Homo sapiens OX=9606 GN=CCT7 PE=1 SV=2 8.59 2922.4 - 9.21E+06 - - - -3.0297 - 1.979 0.345 - 587.8 1 2 0 -0.0034 10 0 0 0 1.84E+07 1.33E+08 - - - 3.4934 0.994 221125_WJC_METTL3_EV_vs_WT_F03.16352.16352.2 0.000678 16-Oct K.SDVETIFSK.Y "sp|Q9UKM9|RALY_HUMAN,tr|Q5QPM2|Q5QPM2_HUMAN,tr|Q5QPM1|Q5QPM1_HUMAN,tr|Q5QPL9|Q5QPL9_HUMAN" 4 1024.5077 1.1 31728 16352 2 1024.512787 513.2611 RNA-binding protein Raly OS=Homo sapiens OX=9606 GN=RALY PE=1 SV=1 4.37 2922.5 - 5.51E+06 - - - 4.9741 - 1.526 0.443 - 237.7 1 2 0 0.0051 9 0 0 0 2.93E+07 2.65E+07 - - - 3.5341 0.9974 221125_WJC_METTL3_EV_vs_WT_F03.16353.16353.2 0.152 16-Jul K.EEQLQQILK.R "sp|P51948|MAT1_HUMAN,tr|H0YJF2|H0YJF2_HUMAN,tr|H0YJ92|H0YJ92_HUMAN" 3 1127.6186 1.7 31729 16353 2 1127.6196 564.8166 CDK-activating kinase assembly factor MAT1 OS=Homo sapiens OX=9606 GN=MNAT1 PE=1 SV=1 4.53 2922.6 - 1.33E+06 - - - 0.8522 - 1.485 0.214 - 172 1 2 0 0.001 9 0 0 0 4.61E+07 2.71E+07 - - - 1.7653 0.9998 221125_WJC_METTL3_EV_vs_WT_F03.16354.16354.2 0.000449 18-Nov K.QQLLIGAYAK.A sp|Q99832|TCPH_HUMAN 1 1103.6339 0.14 31730 16354 2 1103.633922 552.8242 T-complex protein 1 subunit eta OS=Homo sapiens OX=9606 GN=CCT7 PE=1 SV=2 8.59 2922.7 - 1.26E+06 - - - 0.0245 - 2.204 0.413 - 444.7 1 2 0 0 10 0 0 0 1.84E+07 1.34E+08 - - - 4.2973 0.9998 221125_WJC_METTL3_EV_vs_WT_F03.16356.16356.2 0.000326 18-Oct R.DVFYYSPSGK.K sp|O95983|MBD3_HUMAN 1 1161.5342 1.59 31732 16356 2 1161.533366 581.7744 Methyl-CpG-binding domain protein 3 OS=Homo sapiens OX=9606 GN=MBD3 PE=1 SV=1 5.83 2922.9 - 1.22E+06 - - - -0.7525 - 1.754 0.49 - 377.5 1 2 0 -0.0009 10 0 0 0 2.34E+07 1.47E+07 - - - 4.2283 1 221125_WJC_METTL3_EV_vs_WT_F03.16357.16357.2 1.28E-09 19/30 R.VADFTEQYNEQYGAVR[166.11].T sp|Q9BQ04|RBM4B_HUMAN 1 1898.8674 1.58 31733 16357 2 1898.863832 950.441 RNA-binding protein 4B OS=Homo sapiens OX=9606 GN=RBM4B PE=1 SV=1 4.14 2923 - 1.19E+06 - - - -1.8927 - 3.681 0.707 - 1409.9 1 2 0 -0.0036 16 0 0 0 2.87E+07 1.81E+07 - - - 7.4657 0.9984 221125_WJC_METTL3_EV_vs_WT_F03.16358.16358.2 0.264 14-Aug R.NLLSVAYK.N "sp|P31946|1433B_HUMAN,sp|P62258|1433E_HUMAN,sp|P27348|1433T_HUMAN,sp|P63104|1433Z_HUMAN,sp|Q04917|1433F_HUMAN,sp|P31947|1433S_HUMAN,sp|P61981|1433G_HUMAN,tr|E7EX29|E7EX29_HUMAN,tr|Q4VY19|Q4VY19_HUMAN,tr|B4DJF2|B4DJF2_HUMAN,tr|A0A0J9YWZ2|A0A0J9YWZ2_HUMAN,tr|Q4VY20|Q4VY20_HUMAN,tr|A2IDB2|A2IDB2_HUMAN,tr|E5RIR4|E5RIR4_HUMAN,tr|E9PG15|E9PG15_HUMAN,tr|I3L3T1|I3L3T1_HUMAN,tr|K7EIT4|K7EIT4_HUMAN,tr|E7EVZ2|E7EVZ2_HUMAN,tr|E5RGE1|E5RGE1_HUMAN,tr|E9PD24|E9PD24_HUMAN,tr|A0A0J9YWE8|A0A0J9YWE8_HUMAN,tr|E7ESK7|E7ESK7_HUMAN" 22 906.5175 2.38 31734 16358 2 906.515472 454.266 14-3-3 protein beta\alpha OS=Homo sapiens OX=9606 GN=YWHAB PE=1 SV=3 8.59 2923.1 - 1.04E+06 - - - -2.2018 - 1.729 0.285 - 162 1 2 0 -0.002 8 0 0 0 1.49E+07 6.26E+06 - - - 2.7967 0.9935 221125_WJC_METTL3_EV_vs_WT_F03.16360.16360.2 0.0883 22-Nov R.SALAPNLLTSGK[136.11].K sp|O15446|RPA34_HUMAN 1 1178.675 1.17 31736 16360 2 1178.668728 590.3448 DNA-directed RNA polymerase I subunit RPA34 OS=Homo sapiens OX=9606 GN=POLR1G PE=1 SV=1 8.47 2923.3 - 762529 - - - -5.3535 - 2.197 0.354 - 228.9 1 2 0 -0.0063 12 0 0 0 1.58E+07 1.35E+07 - - - 3.7246 0.9997 221125_WJC_METTL3_EV_vs_WT_F03.16363.16363.2 2.72E-05 18-Dec K.SSEQILATLK[136.11].G sp|Q9UMS4|PRP19_HUMAN 1 1096.6219 1.29 31737 16363 2 1096.62145 549.3182 Pre-mRNA-processing factor 19 OS=Homo sapiens OX=9606 GN=PRPF19 PE=1 SV=1 5.72 2923.7 - 1.45E+07 - - - -0.4468 - 2.312 0.291 - 776.9 1 2 0 -0.0005 10 0 0 0 5.01E+08 3.88E+08 - - - 3.5296 0.9846 221125_WJC_METTL3_EV_vs_WT_F03.16364.16364.2 0.000172 16-Sep C.AVEFNFGQK[136.11].E "sp|Q00839|HNRPU_HUMAN,tr|A0A1W2PQL0|A0A1W2PQL0_HUMAN,tr|A0A1W2PPL4|A0A1W2PPL4_HUMAN,tr|A0A1W2PQ74|A0A1W2PQ74_HUMAN,tr|Q5RI18|Q5RI18_HUMAN,tr|A0A1W2PP35|A0A1W2PP35_HUMAN,tr|A0A1W2PPS1|A0A1W2PPS1_HUMAN,tr|A0A1W2PRZ7|A0A1W2PRZ7_HUMAN,tr|A0A1W2PPH7|A0A1W2PPH7_HUMAN,tr|A0A1W2PP34|A0A1W2PP34_HUMAN,tr|A0A1X7SBS1|A0A1X7SBS1_HUMAN" 11 1046.5276 1 31738 16364 2 1046.527542 524.2711 Heterogeneous nuclear ribonucleoprotein U OS=Homo sapiens OX=9606 GN=HNRNPU PE=1 SV=6 6.05 2923.8 - 3.74E+06 - - - -0.0984 - 1.667 0.435 - 248.4 1 1 0 -0.0001 9 0 0 0 6.79E+07 6.77E+07 - - - 3.7323 0.9996 221125_WJC_METTL3_EV_vs_WT_F03.16365.16365.3 0.126 Dec-40 K.GKPLALVEEIR.N "sp|Q9BSD7|NTPCR_HUMAN,tr|Q5TDF0|Q5TDF0_HUMAN" 2 1223.7238 1.2 31739 16365 3 1223.726387 408.9152 Cancer-related nucleoside-triphosphatase OS=Homo sapiens OX=9606 GN=NTPCR PE=1 SV=1 6.14 2923.8 - 2.53E+06 - - - 2.1369 - 2.629 0.303 - 232.6 1 2 0 0.0026 11 0 0 0 8.91E+08 7.42E+08 - - - 4.6634 0.9997 221125_WJC_METTL3_EV_vs_WT_F03.16368.16368.2 1.77E-05 18-Oct K.NNWEVSALSR.A sp|P78527|PRKDC_HUMAN 1 1174.5731 0.72 31742 16368 2 1174.571405 588.2938 DNA-dependent protein kinase catalytic subunit OS=Homo sapiens OX=9606 GN=PRKDC PE=1 SV=3 6 2924.1 - 1.18E+06 - - - -1.4303 - 1.881 0.464 - 437.9 1 2 0 -0.0017 10 0 0 0 1.56E+07 2.16E+07 - - - 4.2311 0.9933 221125_WJC_METTL3_EV_vs_WT_F03.16369.16369.2 0.000559 28-Dec K.VALVYGQMNEPPGAR.A "sp|P06576|ATPB_HUMAN,tr|F8W0P7|F8W0P7_HUMAN,tr|H0YH81|H0YH81_HUMAN" 3 1600.8032 1.57 31743 16369 2 1600.806752 801.4089 "ATP synthase subunit beta, mitochondrial OS=Homo sapiens OX=9606 GN=ATP5F1B PE=1 SV=3" 5.97 2924.2 - 767907 - - - 2.2426 - 2.228 0.083 - 527.2 1 2 0 0.0036 15 0 0 0 1.51E+07 9.65E+06 - - - 1.6225 0.8645 221125_WJC_METTL3_EV_vs_WT_F03.16373.16373.2 0.00345 22-Aug R.TSSSLTPIGHSF.Y "sp|Q14671|PUM1_HUMAN,tr|Q5T1Z8|Q5T1Z8_HUMAN,tr|H0YDK8|H0YDK8_HUMAN,tr|H0YCK1|H0YCK1_HUMAN,tr|Q5T1Z4|Q5T1Z4_HUMAN,tr|E9PR38|E9PR38_HUMAN" 6 1232.6037 - 31745 16373 2 1232.601374 617.3091 Pumilio homolog 1 OS=Homo sapiens OX=9606 GN=PUM1 PE=1 SV=3 6.4 2924.7 - 1.72E+06 - - - -1.9009 - 1.69 0.234 - 204.8 1 1 0 -0.0023 12 0 0 0 - - - - - 2.1492 0.9961 221125_WJC_METTL3_EV_vs_WT_F03.16374.16374.2 0.0305 20-Sep K.LVTDEDVFPTK[136.11].Y "sp|Q70IA6|MOB2_HUMAN,tr|A0A087WVS8|A0A087WVS8_HUMAN" 2 1270.6536 2.42 31746 16374 2 1270.652553 636.3341 MOB kinase activator 2 OS=Homo sapiens OX=9606 GN=MOB2 PE=1 SV=1 4.03 2924.9 - 621604 - - - -0.8507 - 1.539 0.157 - 193.2 1 2 0 -0.0011 11 0 0 0 4.52E+07 1.87E+07 - - - 1.3666 0.9994 221125_WJC_METTL3_EV_vs_WT_F03.16375.16375.2 1.85E-06 24-Nov K.YAQGADSVEPMFR[166.11].H "sp|Q9UKV8|AGO2_HUMAN,sp|Q9UL18|AGO1_HUMAN,sp|Q9H9G7|AGO3_HUMAN,tr|A0A6I8PTZ8|A0A6I8PTZ8_HUMAN,tr|Q5TA58|Q5TA58_HUMAN" 5 1479.6692 1.81 31747 16375 2 1479.672474 740.8419 Protein argonaute-2 OS=Homo sapiens OX=9606 GN=AGO2 PE=1 SV=3 4.37 2925 - 477366 - - - 2.2235 - 2.045 0.413 - 115.9 1 2 0 0.0033 13 0 0 0 1.26E+07 6.93E+06 - - - 3.9265 0.9999 221125_WJC_METTL3_EV_vs_WT_F03.16378.16378.2 1.83E-06 18-Nov K.NMQDMVEDYR.N sp|P04264|K2C1_HUMAN 1 1299.5224 4017.33 31748 16378 2 1299.522691 650.7685 "Keratin, type II cytoskeletal 1 OS=Homo sapiens OX=9606 GN=KRT1 PE=1 SV=6" 4.03 2925.4 - 3.57E+06 - - - 0.2455 - 2.235 0.597 - 473.9 1 2 0 0.0003 10 0 0 0 5.56E+09 1.38E+06 - - - 5.6952 1 221125_WJC_METTL3_EV_vs_WT_F03.16379.16379.3 1.36E-08 17/48 R.LLVGNDDVHIIAR[166.11].S sp|Q7Z6Z7|HUWE1_HUMAN 1 1443.8073 0.86 31749 16379 3 1443.807267 482.2764 E3 ubiquitin-protein ligase HUWE1 OS=Homo sapiens OX=9606 GN=HUWE1 PE=1 SV=3 5.21 2925.5 - 2.43E+06 - - - -0.0457 - 3.146 0.583 - 530.3 1 2 0 -0.0001 13 0 0 0 2.95E+07 3.43E+07 - - - 8.1474 0.9998 221125_WJC_METTL3_EV_vs_WT_F03.16382.16382.2 0.00335 24-Oct R.LLTIGDANGEIQR[166.11].H "sp|Q86X55|CARM1_HUMAN,tr|K7EPK1|K7EPK1_HUMAN,tr|K7EK20|K7EK20_HUMAN" 3 1408.755 0.87 31752 16382 2 1408.755936 705.3848 Histone-arginine methyltransferase CARM1 OS=Homo sapiens OX=9606 GN=CARM1 PE=1 SV=3 4.37 2925.8 - 618188 - - - 0.6907 - 2.223 0.447 - 344.2 1 2 0 0.001 13 0 0 0 2.08E+07 2.38E+07 - - - 4.3925 0.9997 221125_WJC_METTL3_EV_vs_WT_F03.16386.16386.2 0.00084 16-Oct K.TLLDIDNTR.M sp|P35527|K1C9_HUMAN 1 1059.556 70.48 31755 16386 2 1059.556664 530.7853 "Keratin, type I cytoskeletal 9 OS=Homo sapiens OX=9606 GN=KRT9 PE=1 SV=3" 4.21 2926.2 - 2.48E+06 - - - 0.5908 - 1.84 0.379 - 330.8 1 2 0 0.0006 9 0 0 0 4.45E+07 6.32E+05 - - - 3.6042 0.9999 221125_WJC_METTL3_EV_vs_WT_F03.16387.16387.3 0.000751 Oct-40 K.GK[136.11]PLALVEEIR[166.11].N "sp|Q9BSD7|NTPCR_HUMAN,tr|Q5TDF0|Q5TDF0_HUMAN" 2 1241.7462 1.2 31756 16387 3 1241.745392 414.9227 Cancer-related nucleoside-triphosphatase OS=Homo sapiens OX=9606 GN=NTPCR PE=1 SV=1 6.14 2926.2 - 1.07E+07 - - - -0.6845 - 2.137 0.409 - 200.5 1 2 0 -0.0008 11 0 0 0 8.92E+08 7.42E+08 - - - 5.257 0.9998 221125_WJC_METTL3_EV_vs_WT_F03.16388.16388.2 3.81E-05 20-Nov K.GK[136.11]PLALVEEIR[166.11].N "sp|Q9BSD7|NTPCR_HUMAN,tr|Q5TDF0|Q5TDF0_HUMAN" 2 1241.7462 1.08 31757 16388 2 1241.745461 621.8804 Cancer-related nucleoside-triphosphatase OS=Homo sapiens OX=9606 GN=NTPCR PE=1 SV=1 6.14 2926.2 - 3.39E+06 - - - -0.629 - 2.011 0.458 - 470.7 1 2 0 -0.0008 11 0 0 0 2.86E+08 2.65E+08 - - - 4.3135 0.8173 221125_WJC_METTL3_EV_vs_WT_F03.16390.16390.2 0.199 18-Aug Q.EGVSMEVLER[166.11].N "sp|Q5TCZ1|SPD2A_HUMAN,tr|H0Y507|H0Y507_HUMAN" 2 1157.5626 0.63 31759 16390 2 1157.560985 579.7886 SH3 and PX domain-containing protein 2A OS=Homo sapiens OX=9606 GN=SH3PXD2A PE=1 SV=1 4.25 2926.5 - 681628 - - - -1.39 - 1.437 0.228 - 159.6 2 1 0 -0.0016 10 0 0 0 9.58E+06 1.52E+07 - - - 1.602 0.9997 221125_WJC_METTL3_EV_vs_WT_F03.16391.16391.2 0.0007 18-Jul R.DLGFNGAPYR[166.11].S sp|Q9Y5B9|SP16H_HUMAN 1 1118.5384 0.63 31760 16391 2 1118.536968 560.2765 FACT complex subunit SPT16 OS=Homo sapiens OX=9606 GN=SUPT16H PE=1 SV=1 5.84 2926.6 - 508996 - - - -1.3053 - 1.653 0.463 - 106.8 1 2 0 -0.0015 10 0 0 0 9.92E+06 1.58E+07 - - - 3.8631 0.9937 221125_WJC_METTL3_EV_vs_WT_F03.16393.16393.3 0.516 Aug-36 K.LAELEEALQK.A "sp|P13647|K2C5_HUMAN,tr|H0YI76|H0YI76_HUMAN" 2 1142.6183 14.14 31762 16393 3 1142.61742 381.88 "Keratin, type II cytoskeletal 5 OS=Homo sapiens OX=9606 GN=KRT5 PE=1 SV=3" 4.25 2926.9 - 309076 - - - -0.7737 - 1.549 0.204 - 84.1 1 2 0 -0.0009 10 0 0 0 5.28E+06 3.73E+05 - - - 2.0922 0.9999 221125_WJC_METTL3_EV_vs_WT_F03.16395.16395.2 6.45E-05 14/24 R.AAVSAFPTDSLER.D "sp|O14654|IRS4_HUMAN,tr|A0A804CF45|A0A804CF45_HUMAN" 2 1362.6779 1.11 31763 16395 2 1362.677573 682.3462 Insulin receptor substrate 4 OS=Homo sapiens OX=9606 GN=IRS4 PE=1 SV=1 4.37 2927.1 - 1.46E+07 - - - -0.273 - 2.744 0.475 - 494.7 1 2 0 -0.0004 13 0 0 0 2.84E+08 2.56E+08 - - - 5.1399 0.9999 221125_WJC_METTL3_EV_vs_WT_F03.16396.16396.2 9.63E-07 24-Dec R.TTPSYVAFTDTER[166.11].L "sp|P48741|HSP77_HUMAN,sp|P54652|HSP72_HUMAN,sp|P0DMV8|HS71A_HUMAN,sp|P34931|HS71L_HUMAN,sp|P11142|HSP7C_HUMAN,sp|P0DMV9|HS71B_HUMAN,sp|P17066|HSP76_HUMAN,tr|E9PQQ4|E9PQQ4_HUMAN,tr|E9PNE6|E9PNE6_HUMAN,tr|E9PKE3|E9PKE3_HUMAN,tr|E9PLF4|E9PLF4_HUMAN,tr|Q53FA3|Q53FA3_HUMAN,tr|E9PI65|E9PI65_HUMAN,tr|E9PK54|E9PK54_HUMAN,tr|E9PN25|E9PN25_HUMAN,tr|E9PPY6|E9PPY6_HUMAN,tr|E9PQK7|E9PQK7_HUMAN,tr|A0A0G2JIW1|A0A0G2JIW1_HUMAN" 18 1496.7023 0.12 31764 16396 2 1496.699832 749.3584 Putative heat shock 70 kDa protein 7 OS=Homo sapiens OX=9606 GN=HSPA7 PE=5 SV=2 4.37 2927.2 - 1.59E+06 - - - -1.6216 - 2.427 0.587 - 405.3 1 2 0 -0.0024 13 0 0 0 1.18E+07 9.45E+07 - - - 5.6514 1 221125_WJC_METTL3_EV_vs_WT_F03.16398.16398.2 6.92E-08 15/24 K.VDEIVVLSGDNSK[136.11].V "sp|Q14254|FLOT2_HUMAN,tr|E7EMK3|E7EMK3_HUMAN,tr|J3QLD9|J3QLD9_HUMAN" 3 1381.718 0.61 31766 16398 2 1381.717904 691.8663 Flotillin-2 OS=Homo sapiens OX=9606 GN=FLOT2 PE=1 SV=2 4.03 2927.4 - 1.89E+06 - - - -0.0876 - 2.954 0.58 - 1050.5 1 2 0 -0.0001 13 0 0 0 1.53E+07 2.49E+07 - - - 6.1048 0.9995 221125_WJC_METTL3_EV_vs_WT_F03.16399.16399.2 0.00491 16-Sep K.QNTGVWLVK[136.11].V sp|P13984|T2FB_HUMAN 1 1051.5906 1.2 31767 16399 2 1051.590068 526.8026 General transcription factor IIF subunit 2 OS=Homo sapiens OX=9606 GN=GTF2F2 PE=1 SV=2 8.75 2927.5 - 1.36E+06 - - - -0.4869 - 1.832 0.301 - 291.5 1 2 0 -0.0005 9 0 0 0 2.75E+07 2.28E+07 - - - 3.0155 0.9999 221125_WJC_METTL3_EV_vs_WT_F03.16401.16401.2 1.74E-05 14/26 K.NGIAGSSLPPPPIK.H sp|Q9Y5A9|YTHD2_HUMAN 1 1346.7558 3.45 31769 16401 2 1346.754684 674.3852 YTH domain-containing family protein 2 OS=Homo sapiens OX=9606 GN=YTHDF2 PE=1 SV=2 8.75 2927.7 - 1.12E+06 - - - -0.8294 - 2.27 0.49 - 698.8 1 2 0 -0.0011 14 0 0 0 3.08E+07 8.93E+06 - - - 4.717 0.9997 221125_WJC_METTL3_EV_vs_WT_F03.16402.16402.3 0.0132 Sep-32 K.FYVHNDIFR.Y "sp|Q13283|G3BP1_HUMAN,tr|A0A7I2V5M7|A0A7I2V5M7_HUMAN,tr|A0A7P0P2U7|A0A7P0P2U7_HUMAN,tr|A0A7I2YQU8|A0A7I2YQU8_HUMAN,tr|A0A7I2V651|A0A7I2V651_HUMAN,tr|A0A7I2YQN9|A0A7I2YQN9_HUMAN,tr|A0A7I2V2V1|A0A7I2V2V1_HUMAN" 7 1209.5931 1.12 31770 16402 3 1209.592673 404.205 Ras GTPase-activating protein-binding protein 1 OS=Homo sapiens OX=9606 GN=G3BP1 PE=1 SV=1 6.74 2927.8 - 1.09E+06 - - - -0.3472 - 1.655 0.375 - 77.8 1 2 0 -0.0004 9 0 0 0 7.52E+08 6.72E+08 - - - 4.2391 0.9999 221125_WJC_METTL3_EV_vs_WT_F03.16403.16403.2 3.84E-07 14/26 R.VAVEYLDPSPEVQK[136.11].K "sp|O43684|BUB3_HUMAN,tr|J3QT28|J3QT28_HUMAN" 2 1580.8177 0.74 31771 16403 2 1580.816713 791.4161 Mitotic checkpoint protein BUB3 OS=Homo sapiens OX=9606 GN=BUB3 PE=1 SV=1 4.14 2927.9 - 1.01E+06 - - - -0.649 - 2.464 0.534 - 536.3 1 2 0 -0.001 14 0 0 0 4.19E+07 5.67E+07 - - - 5.2478 1 221125_WJC_METTL3_EV_vs_WT_F03.16404.16404.3 1.99E-06 15/48 R.GTMIPSEAPLLHR.Q "sp|Q96A35|RM24_HUMAN,tr|X6RJ73|X6RJ73_HUMAN" 2 1420.7497 1.61 31772 16404 3 1420.749177 474.5905 "39S ribosomal protein L24, mitochondrial OS=Homo sapiens OX=9606 GN=MRPL24 PE=1 SV=1" 6.75 2928 - 817613 - - - -0.347 - 2.473 0.508 - 365.2 1 2 0 -0.0005 13 0 0 0 1.48E+07 9.21E+06 - - - 6.6584 0.9999 221125_WJC_METTL3_EV_vs_WT_F03.16406.16406.3 0.000246 13/48 K.SNNIFLHEGLTVK[136.11].L "sp|P10398|ARAF_HUMAN,sp|P04049|RAF1_HUMAN,tr|H7C155|H7C155_HUMAN" 3 1478.7973 0.56 31774 16406 3 1478.794071 493.9397 Serine\threonine-protein kinase A-Raf OS=Homo sapiens OX=9606 GN=ARAF PE=1 SV=2 6.47 2928.3 - 573516 - - - -2.1687 - 2.628 0.394 - 266.7 1 2 0 -0.0032 13 0 0 0 3.35E+06 6.03E+06 - - - 5.5515 0.9929 221125_WJC_METTL3_EV_vs_WT_F03.16407.16407.2 1.00E-06 Nov-34 R.HLLPNSGAAATSAAMAAA.A sp|Q9BQ04|RBM4B_HUMAN 1 1623.8039 - 31775 16407 2 1623.80342 812.9092 RNA-binding protein 4B OS=Homo sapiens OX=9606 GN=RBM4B PE=1 SV=1 6.74 2928.4 - 439233 - - - -0.2894 - 2.325 0.51 - 212.6 1 1 0 -0.0005 18 0 0 0 - - - - - 4.882 0.9999 221125_WJC_METTL3_EV_vs_WT_F03.16410.16410.2 7.52E-07 18-Oct K.TEVNSGFFYK[136.11].T "sp|Q92526|TCPW_HUMAN,sp|P40227|TCPZ_HUMAN,tr|J3KRI6|J3KRI6_HUMAN" 3 1198.575 0.46 31776 16410 2 1198.575878 600.2948 T-complex protein 1 subunit zeta-2 OS=Homo sapiens OX=9606 GN=CCT6B PE=1 SV=5 5.66 2928.8 - 1.10E+07 - - - 0.7417 - 2.268 0.54 - 349.5 1 2 0 0.0009 10 0 0 0 2.46E+08 5.40E+08 - - - 5.315 0.9998 221125_WJC_METTL3_EV_vs_WT_F03.16411.16411.2 0.000657 20-Nov R.QITVNDLPVGR.S "sp|Q06830|PRDX1_HUMAN,sp|P32119|PRDX2_HUMAN,tr|A0A0A0MRQ5|A0A0A0MRQ5_HUMAN,tr|A0A0A0MSI0|A0A0A0MSI0_HUMAN" 4 1210.667 0.79 31777 16411 2 1210.665826 606.3408 Peroxiredoxin-1 OS=Homo sapiens OX=9606 GN=PRDX1 PE=1 SV=1 5.84 2928.9 - 7.36E+06 - - - -0.9581 - 2.185 0.423 - 506.1 1 2 0 -0.0012 11 0 0 0 1.23E+09 1.54E+09 - - - 4.2794 0.992 221125_WJC_METTL3_EV_vs_WT_F03.16412.16412.3 0.0592 Sep-36 K.MREEVITLIR.S "sp|P46940|IQGA1_HUMAN,tr|H0YLE8|H0YLE8_HUMAN,tr|A0A0J9YXZ5|A0A0J9YXZ5_HUMAN" 3 1258.7067 0.9 31778 16412 3 1258.704372 420.5762 Ras GTPase-activating-like protein IQGAP1 OS=Homo sapiens OX=9606 GN=IQGAP1 PE=1 SV=1 5.9 2928.9 - 2.55E+06 - - - -1.8829 - 1.954 0.249 - 180.5 1 2 1 -0.0024 10 0 0 0 2.37E+07 2.64E+07 - - - 3.2718 1 221125_WJC_METTL3_EV_vs_WT_F03.16413.16413.2 4.26E-06 15/24 K.TAVVVGTITDDVR[166.11].V "sp|Q07020|RL18_HUMAN,tr|J3QQ67|J3QQ67_HUMAN,tr|F8VUA6|F8VUA6_HUMAN,tr|G3V203|G3V203_HUMAN,tr|F8VYV2|F8VYV2_HUMAN,tr|H0YHA7|H0YHA7_HUMAN,tr|A0A075B7A0|A0A075B7A0_HUMAN" 7 1354.7332 0.84 31779 16413 2 1354.725578 678.3739 60S ribosomal protein L18 OS=Homo sapiens OX=9606 GN=RPL18 PE=1 SV=2 4.21 2929 - 1.75E+06 - - - -5.6004 - 2.833 0.561 - 843.9 1 2 0 -0.0076 13 0 0 0 1.34E+08 1.60E+08 - - - 5.8548 0.9998 221125_WJC_METTL3_EV_vs_WT_F03.16417.16417.2 4.33E-05 24-Nov K.YNVSTTPYLQSVK[136.11].K sp|Q8WWK9|CKAP2_HUMAN 1 1506.781 1.05 31783 16417 2 1506.779456 754.3978 Cytoskeleton-associated protein 2 OS=Homo sapiens OX=9606 GN=CKAP2 PE=1 SV=1 8.5 2929.5 - 939788 - - - -0.9982 - 2.104 0.47 - 315.1 1 2 0 -0.0015 13 0 0 0 1.76E+07 1.67E+07 - - - 4.421 0.9998 221125_WJC_METTL3_EV_vs_WT_F03.16423.16423.2 0.0764 18-Nov K.SSEQILATLK.G sp|Q9UMS4|PRP19_HUMAN 1 1088.6077 1.29 31788 16423 2 1088.607465 545.3111 Pre-mRNA-processing factor 19 OS=Homo sapiens OX=9606 GN=PRPF19 PE=1 SV=1 5.72 2930.2 - 3.30E+07 - - - -0.2526 - 2.303 0.382 - 699.1 1 2 0 -0.0003 10 0 0 0 5.01E+08 3.88E+08 - - - 4.1909 0.9998 221125_WJC_METTL3_EV_vs_WT_F03.16425.16425.2 0.00168 20-Nov R.QITVNDLPVGR[166.11].S "sp|Q06830|PRDX1_HUMAN,sp|P32119|PRDX2_HUMAN,tr|A0A0A0MRQ5|A0A0A0MRQ5_HUMAN,tr|A0A0A0MSI0|A0A0A0MSI0_HUMAN" 4 1220.6753 0.79 31789 16425 2 1220.674275 611.3449 Peroxiredoxin-1 OS=Homo sapiens OX=9606 GN=PRDX1 PE=1 SV=1 5.84 2930.5 - 3.12E+07 - - - -0.8037 - 2.082 0.406 - 599.5 1 2 0 -0.001 11 0 0 0 1.22E+09 1.54E+09 - - - 4.0232 0.9995 221125_WJC_METTL3_EV_vs_WT_F03.16426.16426.2 0.00623 16-Nov K.TIQVLQIEK.V "sp|Q15643|TRIPB_HUMAN,tr|H0YJ97|H0YJ97_HUMAN" 2 1070.6336 1.14 31790 16426 2 1070.634515 536.3241 Thyroid receptor-interacting protein 11 OS=Homo sapiens OX=9606 GN=TRIP11 PE=1 SV=3 5.66 2930.5 - 1.18E+07 - - - 0.892 - 2.005 0.286 - 315.5 1 2 0 0.001 9 0 0 0 3.47E+08 3.04E+08 - - - 3.1656 0.9996 221125_WJC_METTL3_EV_vs_WT_F03.16427.16427.2 0.0065 16-Oct K.TIQVLQIEK[136.11].V "sp|Q15643|TRIPB_HUMAN,tr|H0YJ97|H0YJ97_HUMAN" 2 1078.6478 1.14 31791 16427 2 1078.647551 540.3312 Thyroid receptor-interacting protein 11 OS=Homo sapiens OX=9606 GN=TRIP11 PE=1 SV=3 5.66 2930.6 - 1.06E+07 - - - -0.1938 - 1.88 0.317 - 243.8 1 2 0 -0.0002 9 0 0 0 3.46E+08 3.04E+08 - - - 3.2086 0.9995 221125_WJC_METTL3_EV_vs_WT_F03.16429.16429.3 0.00342 13/40 K.KFAEAFEAIPR.A sp|P50990|TCPQ_HUMAN 1 1277.6768 0.21 31793 16429 3 1277.677087 426.8996 T-complex protein 1 subunit theta OS=Homo sapiens OX=9606 GN=CCT8 PE=1 SV=4 6.14 2930.7 - 2.37E+06 - - - 0.2074 - 1.864 0.32 - 225.3 1 2 0 0.0003 11 0 0 0 3.00E+07 1.44E+08 - - - 3.8767 1 221125_WJC_METTL3_EV_vs_WT_F03.16431.16431.2 5.69E-11 13/28 R.MGLAMGGGGGASFDR[166.11].A "sp|P52272|HNRPM_HUMAN,tr|M0R2I7|M0R2I7_HUMAN,tr|M0QY96|M0QY96_HUMAN,tr|A0A087X0X3|A0A087X0X3_HUMAN" 4 1392.6154 1.76 31795 16431 2 1392.612737 697.315 Heterogeneous nuclear ribonucleoprotein M OS=Homo sapiens OX=9606 GN=HNRNPM PE=1 SV=3 5.59 2930.9 - 1.29E+06 - - - -1.8943 - 3.037 0.68 - 534.2 1 2 0 -0.0026 15 0 0 0 5.29E+08 3.01E+08 - - - 6.7938 0.9997 221125_WJC_METTL3_EV_vs_WT_F03.16432.16432.2 0.00427 20-Nov K.TAVLTAFANGR.S "sp|O96019|ACL6A_HUMAN,sp|O94805|ACL6B_HUMAN" 2 1119.6037 0.9 31796 16432 2 1119.601415 560.8091 Actin-like protein 6A OS=Homo sapiens OX=9606 GN=ACTL6A PE=1 SV=1 9.41 2931.1 - 1.02E+06 - - - -2.0025 - 2.368 0.413 - 441.7 1 2 0 -0.0022 11 0 0 0 1.18E+07 1.31E+07 - - - 4.4228 0.9999 221125_WJC_METTL3_EV_vs_WT_F03.16433.16433.3 0.000561 15/48 R.VLVDGEEHVGFLK.T "sp|Q9NPA0|EMC7_HUMAN,tr|H0YDT8|H0YDT8_HUMAN" 2 1440.7613 1.4 31797 16433 3 1440.760533 481.261 ER membrane protein complex subunit 7 OS=Homo sapiens OX=9606 GN=EMC7 PE=1 SV=1 4.65 2931.2 - 942601 - - - -0.5185 - 2.563 0.42 - 256 1 2 0 -0.0007 13 0 0 0 2.82E+07 2.01E+07 - - - 5.7742 0.999 221125_WJC_METTL3_EV_vs_WT_F03.16434.16434.2 4.89E-05 13/24 R.LAETQNIAPSFVK.G "sp|Q96TA2|YMEL1_HUMAN,tr|Q96I63|Q96I63_HUMAN,tr|Q5T8D1|Q5T8D1_HUMAN,tr|Q5T8D2|Q5T8D2_HUMAN" 4 1416.7613 1.53 31798 16434 2 1416.766181 709.3879 ATP-dependent zinc metalloprotease YME1L1 OS=Homo sapiens OX=9606 GN=YME1L1 PE=1 SV=2 6 2931.3 - 933336 - - - 3.4593 - 2.507 0.42 - 595.9 1 2 0 0.0049 13 0 0 0 1.71E+07 1.12E+07 - - - 4.5004 0.9998 221125_WJC_METTL3_EV_vs_WT_F03.16435.16435.3 5.78E-06 13/48 R.VLVDGEEHVGFLK[136.11].T "sp|Q9NPA0|EMC7_HUMAN,tr|H0YDT8|H0YDT8_HUMAN" 2 1448.7755 1.4 31799 16435 3 1448.773363 483.9324 ER membrane protein complex subunit 7 OS=Homo sapiens OX=9606 GN=EMC7 PE=1 SV=1 4.65 2931.4 - 928868 - - - -1.4612 - 2.666 0.342 - 171.4 1 2 0 -0.0021 13 0 0 0 2.82E+07 2.01E+07 - - - 5.011 1 221125_WJC_METTL3_EV_vs_WT_F03.16437.16437.3 4.30E-06 15/48 R.GTMIPSEAPLLHR[166.11].Q "sp|Q96A35|RM24_HUMAN,tr|X6RJ73|X6RJ73_HUMAN" 2 1430.7579 1.73 31801 16437 3 1430.755897 477.9266 "39S ribosomal protein L24, mitochondrial OS=Homo sapiens OX=9606 GN=MRPL24 PE=1 SV=1" 6.75 2931.7 - 719080 - - - -1.4279 - 2.655 0.48 - 353.9 1 2 0 -0.002 13 0 0 0 1.44E+07 8.33E+06 - - - 6.5384 0.9997 221125_WJC_METTL3_EV_vs_WT_F03.16442.16442.2 9.34E-05 24-Nov K.TAVVVGTITDDVR.V "sp|Q07020|RL18_HUMAN,tr|J3QQ67|J3QQ67_HUMAN,tr|F8VUA6|F8VUA6_HUMAN,tr|G3V203|G3V203_HUMAN,tr|F8VYV2|F8VYV2_HUMAN,tr|H0YHA7|H0YHA7_HUMAN,tr|A0A075B7A0|A0A075B7A0_HUMAN" 7 1344.7249 0.81 31804 16442 2 1344.722087 673.3697 60S ribosomal protein L18 OS=Homo sapiens OX=9606 GN=RPL18 PE=1 SV=2 4.21 2932.2 - 7.92E+06 - - - -2.0882 - 2.579 0.466 - 403.8 1 2 0 -0.0028 13 0 0 0 1.34E+08 1.65E+08 - - - 4.9135 1 221125_WJC_METTL3_EV_vs_WT_F03.16443.16443.2 1.61E-12 15/28 R.MGLAMGGGGGASFDR.A "sp|P52272|HNRPM_HUMAN,tr|M0R2I7|M0R2I7_HUMAN,tr|M0QY96|M0QY96_HUMAN,tr|A0A087X0X3|A0A087X0X3_HUMAN" 4 1382.6071 1.72 31805 16443 2 1382.604159 692.3108 Heterogeneous nuclear ribonucleoprotein M OS=Homo sapiens OX=9606 GN=HNRNPM PE=1 SV=3 5.59 2932.3 - 6.12E+06 - - - -2.1308 - 3.17 0.724 - 637.5 1 2 0 -0.0029 15 0 0 0 5.16E+08 3.00E+08 - - - 7.224 0.9997 221125_WJC_METTL3_EV_vs_WT_F03.16444.16444.2 0.000478 18-Nov K.TEVNSGFFYK.T "sp|Q92526|TCPW_HUMAN,sp|P40227|TCPZ_HUMAN,tr|J3KRI6|J3KRI6_HUMAN" 3 1190.5608 0.46 31806 16444 2 1190.560217 596.2877 T-complex protein 1 subunit zeta-2 OS=Homo sapiens OX=9606 GN=CCT6B PE=1 SV=5 5.66 2932.3 - 1.55E+07 - - - -0.4804 - 2.275 0.287 - 467.2 1 2 0 -0.0006 10 0 0 0 2.46E+08 5.40E+08 - - - 3.455 0.9998 221125_WJC_METTL3_EV_vs_WT_F03.16446.16446.2 5.29E-07 17/20 K.HALIIYDDLSK.Q sp|P25705|ATPA_HUMAN 1 1286.6871 1.33 31808 16446 2 1286.685333 644.3508 "ATP synthase subunit alpha, mitochondrial OS=Homo sapiens OX=9606 GN=ATP5F1A PE=1 SV=1" 5.21 2932.4 - 3.30E+06 - - - -1.3368 - 3.33 0.355 - 791.2 1 2 0 -0.0017 11 0 0 0 1.87E+08 1.40E+08 - - - 4.9168 0.9999 221125_WJC_METTL3_EV_vs_WT_F03.16447.16447.3 0.000121 Oct-40 K.HALIIYDDLSK.Q sp|P25705|ATPA_HUMAN 1 1286.6871 0.88 31809 16447 3 1286.685677 429.903 "ATP synthase subunit alpha, mitochondrial OS=Homo sapiens OX=9606 GN=ATP5F1A PE=1 SV=1" 5.21 2932.5 - 2.46E+06 - - - -1.0694 - 2.086 0.451 - 202.5 1 2 0 -0.0014 11 0 0 0 8.65E+07 9.88E+07 - - - 5.6565 0.9998 221125_WJC_METTL3_EV_vs_WT_F03.16448.16448.2 1.93E-05 20-Nov K.LTAFVNTLNGK[136.11].D "sp|P55036|PSMD4_HUMAN,sp|A2A3N6|PIPSL_HUMAN,tr|A6PVX3|A6PVX3_HUMAN,tr|Q5VWC4|Q5VWC4_HUMAN" 4 1184.6645 1.1 31810 16448 2 1184.664475 593.3395 26S proteasome non-ATPase regulatory subunit 4 OS=Homo sapiens OX=9606 GN=PSMD4 PE=1 SV=1 8.75 2932.5 - 2.23E+06 - - - 0.0017 - 1.966 0.481 - 339.5 1 2 0 0 11 0 0 0 3.12E+07 2.85E+07 - - - 4.4224 0.9981 221125_WJC_METTL3_EV_vs_WT_F03.16450.16450.2 0.0117 24-Sep K.YNVSTTPYLQSVK.K sp|Q8WWK9|CKAP2_HUMAN 1 1498.7668 1.07 31812 16450 2 1498.765851 750.3907 Cytoskeleton-associated protein 2 OS=Homo sapiens OX=9606 GN=CKAP2 PE=1 SV=1 8.5 2932.8 - 1.78E+06 - - - -0.6065 - 1.482 0.248 - 94.1 1 2 0 -0.0009 13 0 0 0 1.79E+07 1.67E+07 - - - 1.8821 0.9994 221125_WJC_METTL3_EV_vs_WT_F03.16452.16452.2 5.43E-05 14/20 R.LDTDDLDEIEK[136.11].L "sp|Q9NUU7|DD19A_HUMAN,sp|Q9UMR2|DD19B_HUMAN,tr|F6QDS0|F6QDS0_HUMAN,tr|I3L352|I3L352_HUMAN,tr|H3BQK0|H3BQK0_HUMAN,tr|I3L0H8|I3L0H8_HUMAN" 6 1312.6126 1.31 31814 16452 2 1312.608165 657.3136 ATP-dependent RNA helicase DDX19A OS=Homo sapiens OX=9606 GN=DDX19A PE=1 SV=1 3.66 2932.9 - 1.73E+06 - - - -3.346 - 2.566 0.502 - 496.4 1 2 0 -0.0044 11 0 0 0 2.00E+07 1.52E+07 - - - 5.2967 0.9998 221125_WJC_METTL3_EV_vs_WT_F03.16453.16453.2 9.62E-08 13/24 R.LLTIGDANGEIQR.H "sp|Q86X55|CARM1_HUMAN,tr|K7EPK1|K7EPK1_HUMAN,tr|K7EK20|K7EK20_HUMAN" 3 1398.7467 0.87 31815 16453 2 1398.744029 700.3806 Histone-arginine methyltransferase CARM1 OS=Homo sapiens OX=9606 GN=CARM1 PE=1 SV=3 4.37 2933.1 - 1.70E+06 - - - -1.9046 - 2.394 0.528 - 614.8 1 2 0 -0.0027 13 0 0 0 2.08E+07 2.38E+07 - - - 5.1805 1 221125_WJC_METTL3_EV_vs_WT_F03.16458.16458.2 1.87E-11 15/36 R.LEGLGSSEADQDGLASTVR.S sp|Q07065|CKAP4_HUMAN 1 1903.9123 2.12 31820 16458 2 1903.910861 952.9634 Cytoskeleton-associated protein 4 OS=Homo sapiens OX=9606 GN=CKAP4 PE=1 SV=2 3.92 2933.7 - 539728 - - - -0.7632 - 3.112 0.658 - 437.7 1 2 0 -0.0015 19 0 0 0 3.31E+06 1.56E+06 - - - 6.6916 0.9815 221125_WJC_METTL3_EV_vs_WT_F03.16462.16462.2 9.37E-05 28-Dec K.ELSLAGNELGDEGAR[166.11].L "sp|P13489|RINI_HUMAN,tr|H0YCR7|H0YCR7_HUMAN" 2 1539.7404 0.71 31822 16462 2 1540.740509 770.8775 Ribonuclease inhibitor OS=Homo sapiens OX=9606 GN=RNH1 PE=1 SV=2 4 2934.3 - 1.25E+06 - - - 649.5082 - 2.447 0.433 - 381 1 2 0 1.0001 15 0 0 0 2.63E+07 3.70E+07 - - - 4.1252 0.9992 221125_WJC_METTL3_EV_vs_WT_F03.16463.16463.3 0.00017 Oct-32 K.FYVHNDIFR[166.11].Y "sp|Q13283|G3BP1_HUMAN,tr|A0A7I2V5M7|A0A7I2V5M7_HUMAN,tr|A0A7P0P2U7|A0A7P0P2U7_HUMAN,tr|A0A7I2YQU8|A0A7I2YQU8_HUMAN,tr|A0A7I2V651|A0A7I2V651_HUMAN,tr|A0A7I2YQN9|A0A7I2YQN9_HUMAN,tr|A0A7I2V2V1|A0A7I2V2V1_HUMAN" 7 1219.6014 1.12 31823 16463 3 1219.599729 407.5411 Ras GTPase-activating protein-binding protein 1 OS=Homo sapiens OX=9606 GN=G3BP1 PE=1 SV=1 6.74 2934.3 - 6.38E+07 - - - -1.3398 - 1.848 0.286 - 124.4 1 2 0 -0.0016 9 0 0 0 7.53E+08 6.72E+08 - - - 3.5789 0.9989 221125_WJC_METTL3_EV_vs_WT_F03.16467.16467.2 0.0171 13/20 K.AILNGIDSINK[136.11].V sp|Q9UQE7|SMC3_HUMAN 1 1164.6594 1.04 31827 16467 2 1164.661651 583.337 Structural maintenance of chromosomes protein 3 OS=Homo sapiens OX=9606 GN=SMC3 PE=1 SV=2 5.88 2934.6 - 1.36E+06 - - - 1.9431 - 2.05 0.273 - 429.2 1 2 0 0.0023 11 0 0 0 4.61E+07 4.44E+07 - - - 2.9986 0.9991 221125_WJC_METTL3_EV_vs_WT_F03.16471.16471.2 0.00477 18-Aug K.IDIIPNPQER[166.11].T "sp|P08238|HS90B_HUMAN,sp|Q58FF7|H90B3_HUMAN" 2 1203.6487 1.05 31830 16471 2 1203.647421 602.8316 Heat shock protein HSP 90-beta OS=Homo sapiens OX=9606 GN=HSP90AB1 PE=1 SV=4 4.37 2935.1 - 1.68E+07 - - - -1.0684 - 1.948 0.24 - 189.4 1 2 0 -0.0013 10 0 0 0 3.24E+08 3.09E+08 - - - 2.6745 0.9999 221125_WJC_METTL3_EV_vs_WT_F03.16477.16477.2 0.506 13/18 K.TAEELMNFSK.G "sp|P50990|TCPQ_HUMAN,tr|H7C4C8|H7C4C8_HUMAN" 2 1168.5434 0.36 31835 16477 2 1168.54226 585.279 T-complex protein 1 subunit theta OS=Homo sapiens OX=9606 GN=CCT8 PE=1 SV=4 4.53 2935.6 - 2.17E+06 - - - -0.997 - 2.573 0.451 - 585.5 1 2 0 -0.0012 10 0 0 0 2.77E+08 7.80E+08 - - - 5.0097 1 221125_WJC_METTL3_EV_vs_WT_F03.16480.16480.2 8.39E-15 17/30 A.AYYDQTGALVVNAGAR.N "sp|Q14671|PUM1_HUMAN,tr|Q5T1Z8|Q5T1Z8_HUMAN,tr|H0YDK8|H0YDK8_HUMAN,tr|H0YEH2|H0YEH2_HUMAN,tr|Q5T1Z4|Q5T1Z4_HUMAN,tr|H0YED4|H0YED4_HUMAN,tr|E9PR38|E9PR38_HUMAN" 7 1667.8267 32.7 31838 16480 2 1667.820209 834.9206 Pumilio homolog 1 OS=Homo sapiens OX=9606 GN=PUM1 PE=1 SV=3 5.88 2936 - 836526 - - - -3.9123 - 3.486 0.744 - 1054.4 1 1 0 -0.0065 16 0 0 0 8.19E+06 2.51E+05 - - - 7.6043 0.995 221125_WJC_METTL3_EV_vs_WT_F03.16485.16485.2 0.597 13/20 R.AALQEELQLC[160.03]K[136.11].G "sp|P49327|FAS_HUMAN,tr|A0A0U1RQF0|A0A0U1RQF0_HUMAN" 2 1309.6791 0.01 31841 16485 2 1309.674758 655.8468 Fatty acid synthase OS=Homo sapiens OX=9606 GN=FASN PE=1 SV=3 4.53 2936.6 - 1.49E+06 - - - -3.3436 - 2.021 0.211 - 258.5 1 2 0 -0.0044 11 0 0 0 2.90E+05 2.18E+07 - - - 2.5015 0.9994 221125_WJC_METTL3_EV_vs_WT_F03.16487.16487.2 6.62E-06 20-Dec K.NALESYTYNIK[136.11].Q sp|P54652|HSP72_HUMAN 1 1322.6598 0.53 31843 16487 2 1322.655464 662.3372 Heat shock-related 70 kDa protein 2 OS=Homo sapiens OX=9606 GN=HSPA2 PE=1 SV=1 6 2936.8 - 1.40E+06 - - - -3.2646 - 2.27 0.497 - 493.7 1 2 0 -0.0043 11 0 0 0 1.42E+07 2.70E+07 - - - 4.9282 0.9997 221125_WJC_METTL3_EV_vs_WT_F03.16489.16489.2 1.21E-05 17/28 K.LAQQQAALLMQQEER[166.11].A "sp|Q13435|SF3B2_HUMAN,tr|E9PPJ0|E9PPJ0_HUMAN,tr|H0YCG1|H0YCG1_HUMAN,tr|E9PJ04|E9PJ04_HUMAN,tr|E9PJT3|E9PJT3_HUMAN" 5 1765.902 1 31845 16489 2 1765.898027 883.9583 Splicing factor 3B subunit 2 OS=Homo sapiens OX=9606 GN=SF3B2 PE=1 SV=2 4.53 2937 - 1.20E+06 - - - -2.2714 - 3.573 0.352 - 1393.5 1 2 0 -0.004 15 0 0 0 2.45E+07 2.45E+07 - - - 4.7703 1 221125_WJC_METTL3_EV_vs_WT_F03.16490.16490.3 0.00145 13/40 R.FPEAFSSIHYK[136.11].G "sp|Q9HBF4|ZFYV1_HUMAN,tr|G3V5N8|G3V5N8_HUMAN" 2 1332.6594 0.16 31846 16490 3 1332.658211 445.2271 Zinc finger FYVE domain-containing protein 1 OS=Homo sapiens OX=9606 GN=ZFYVE1 PE=1 SV=1 6.75 2937.1 - 1.13E+06 - - - -0.8832 - 2.374 0.451 - 157.2 1 2 0 -0.0012 11 0 0 0 3.36E+07 2.14E+08 - - - 6.024 0.9717 221125_WJC_METTL3_EV_vs_WT_F03.16491.16491.2 0.932 14-Jun R.NFSVNLYK.V sp|Q9Y512|SAM50_HUMAN 1 983.5076 1.2 31847 16491 2 983.50536 492.7611 Sorting and assembly machinery component 50 homolog OS=Homo sapiens OX=9606 GN=SAMM50 PE=1 SV=3 8.59 2937.3 - 995376 - - - -2.3101 - 1.213 0.129 - 90.2 1 2 0 -0.0023 8 0 0 0 8.70E+06 7.26E+06 - - - 0.5755 1 221125_WJC_METTL3_EV_vs_WT_F03.16492.16492.2 0.000235 17/28 K.LAQQQAALLMQQEER.A "sp|Q13435|SF3B2_HUMAN,tr|E9PPJ0|E9PPJ0_HUMAN,tr|H0YCG1|H0YCG1_HUMAN,tr|E9PJ04|E9PJ04_HUMAN,tr|E9PJT3|E9PJT3_HUMAN" 5 1755.8938 1 31848 16492 2 1755.89308 878.9542 Splicing factor 3B subunit 2 OS=Homo sapiens OX=9606 GN=SF3B2 PE=1 SV=2 4.53 2937.4 - 946086 - - - -0.3918 - 3.476 0.535 - 1212.7 1 2 0 -0.0007 15 0 0 0 2.45E+07 2.45E+07 - - - 6.0554 0.9999 221125_WJC_METTL3_EV_vs_WT_F03.16498.16498.2 1.73E-05 20-Oct K.ITVTSEVPFSK[136.11].R "sp|P35268|RL22_HUMAN,tr|K7EKS7|K7EKS7_HUMAN,tr|K7ERI7|K7ERI7_HUMAN,tr|K7EMH1|K7EMH1_HUMAN,tr|K7ELC4|K7ELC4_HUMAN,tr|K7EP65|K7EP65_HUMAN,tr|K7EJT5|K7EJT5_HUMAN" 7 1214.6638 0.79 31852 16498 2 1214.663202 608.3392 60S ribosomal protein L22 OS=Homo sapiens OX=9606 GN=RPL22 PE=1 SV=2 6 2938.1 - 6.27E+07 - - - -0.4956 - 2.222 0.522 - 275.6 1 2 0 -0.0006 11 0 0 0 1.00E+09 1.26E+09 - - - 5.0562 0.9994 221125_WJC_METTL3_EV_vs_WT_F03.16502.16502.3 0.000818 Nov-56 K.NVIISSAAER[166.11]PLEIR[166.11].G "sp|P78346|RPP30_HUMAN,tr|Q5VU11|Q5VU11_HUMAN" 2 1686.9532 0.87 31856 16502 3 1686.951302 563.325 Ribonuclease P protein subunit p30 OS=Homo sapiens OX=9606 GN=RPP30 PE=1 SV=1 6.14 2938.5 - 844709 - - - -1.1008 - 1.881 0.313 - 150 1 2 0 -0.0019 15 0 0 0 2.54E+07 2.91E+07 - - - 3.6777 0.9998 221125_WJC_METTL3_EV_vs_WT_F03.16508.16508.3 0.000453 Oct-40 K.HALIIYDDLSK[136.11].Q sp|P25705|ATPA_HUMAN 1 1294.7013 0.88 31860 16508 3 1294.699683 432.5744 "ATP synthase subunit alpha, mitochondrial OS=Homo sapiens OX=9606 GN=ATP5F1A PE=1 SV=1" 5.21 2939.2 - 3.70E+06 - - - -1.2126 - 2.029 0.378 - 196.8 1 2 0 -0.0016 11 0 0 0 9.00E+07 1.02E+08 - - - 4.7639 0.9532 221125_WJC_METTL3_EV_vs_WT_F03.16512.16512.2 4.54E-05 24-Nov K.AEGTVFTEEDFQK[136.11].F sp|Q86WX3|AROS_HUMAN 1 1507.6922 1.79 31864 16512 2 1507.678072 754.8534 Active regulator of SIRT1 OS=Homo sapiens OX=9606 GN=RPS19BP1 PE=1 SV=1 4 2939.6 - 596230 - - - -9.3733 - 1.794 0.409 - 171.3 1 2 0 -0.0141 13 0 0 0 1.11E+07 6.19E+06 - - - 3.5574 0.9993 221125_WJC_METTL3_EV_vs_WT_F03.16513.16513.2 0.039 20-Jul R.LQVVDQPLPVR.G "sp|P49327|FAS_HUMAN,tr|A0A0U1RQF0|A0A0U1RQF0_HUMAN" 2 1262.7347 1.03 31865 16513 2 1262.735297 632.3746 Fatty acid synthase OS=Homo sapiens OX=9606 GN=FASN PE=1 SV=3 5.84 2939.8 - 570552 - - - 0.495 - 1.711 0.304 - 171 1 2 0 0.0006 11 0 0 0 1.26E+07 1.22E+07 - - - 2.7391 0.9667 221125_WJC_METTL3_EV_vs_WT_F03.16514.16514.2 0.0747 12-Jun K.VSQWWER[166.11].L "sp|Q9P035|HACD3_HUMAN,tr|H3BPZ1|H3BPZ1_HUMAN,tr|H3BS72|H3BS72_HUMAN" 3 999.4802 1.21 31866 16514 2 999.478025 500.7474 Very-long-chain (3R)-3-hydroxyacyl-CoA dehydratase 3 OS=Homo sapiens OX=9606 GN=HACD3 PE=1 SV=2 5.97 2939.9 - 477956 - - - -2.1611 - 1.526 0.038 - 92.1 4 2 0 -0.0022 7 0 0 0 1.24E+07 1.02E+07 - - - 0.3912 0.9993 221125_WJC_METTL3_EV_vs_WT_F03.16516.16516.2 0.00883 18-Oct K.LEGLEDALQK.A "sp|P48668|K2C6C_HUMAN,sp|P04259|K2C6B_HUMAN,sp|P02538|K2C6A_HUMAN" 3 1114.587 2060.42 31867 16516 2 1114.586681 558.3008 "Keratin, type II cytoskeletal 6C OS=Homo sapiens OX=9606 GN=KRT6C PE=1 SV=3" 4.14 2940.1 - 3.58E+06 - - - -0.2898 - 1.986 0.238 - 257.3 1 2 0 -0.0003 10 0 0 0 2.84E+08 1.38E+05 - - - 2.7139 0.9286 221125_WJC_METTL3_EV_vs_WT_F03.16517.16517.3 0.199 Oct-40 K.FAAQELIEVK[136.11]R[166.11].G "sp|Q86U44|MTA70_HUMAN,tr|F5H6D8|F5H6D8_HUMAN,tr|H0YFV6|H0YFV6_HUMAN,tr|B4DTN4|B4DTN4_HUMAN" 4 1320.7521 0.15 31868 16517 3 1320.749802 441.258 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 6.14 2940.2 - 1.87E+06 - - - -1.7066 - 1.749 0.066 - 91.9 1 2 0 -0.0023 11 0 0 0 7.11E+07 4.88E+08 - - - 0.8634 0.9989 221125_WJC_METTL3_EV_vs_WT_F03.16518.16518.2 7.19E-05 13/20 K.ALNSIIDVYHK.Y sp|P05109|S10A8_HUMAN 1 1271.6874 999 31869 16518 2 1271.692346 636.851 Protein S100-A8 OS=Homo sapiens OX=9606 GN=S100A8 PE=1 SV=1 6.79 2940.2 - 2.95E+06 - - - 3.8995 - 2.597 0.434 - 697.4 1 2 0 0.005 11 0 0 0 1.94E+08 0.00E+00 - - - 4.8267 0.9999 221125_WJC_METTL3_EV_vs_WT_F03.16519.16519.2 1.39E-05 18-Dec R.IVVFQYSDGK[136.11].L "sp|Q16531|DDB1_HUMAN,tr|A0A7P0TAK7|A0A7P0TAK7_HUMAN,tr|A0A7P0T870|A0A7P0T870_HUMAN,tr|A0A7P0TB30|A0A7P0TB30_HUMAN,tr|A0A7P0Z3Z5|A0A7P0Z3Z5_HUMAN,tr|F5GY55|F5GY55_HUMAN,tr|A0A7P0Z4B9|A0A7P0Z4B9_HUMAN,tr|A0A7P0T965|A0A7P0T965_HUMAN" 8 1162.6114 0.71 31870 16519 2 1162.612069 582.313 DNA damage-binding protein 1 OS=Homo sapiens OX=9606 GN=DDB1 PE=1 SV=1 5.83 2940.3 - 2.44E+06 - - - 0.5969 - 2.109 0.515 - 414.2 1 2 0 0.0007 10 0 0 0 2.41E+07 3.38E+07 - - - 4.9275 1 221125_WJC_METTL3_EV_vs_WT_F03.16520.16520.3 0.00117 13/44 K.AFHPFIAGPYNR.L "sp|Q00341|VIGLN_HUMAN,tr|A0A024R4E5|A0A024R4E5_HUMAN,tr|H7C0A4|H7C0A4_HUMAN,tr|H0Y394|H0Y394_HUMAN" 4 1388.699 1.54 31871 16520 3 1388.697953 463.9069 Vigilin OS=Homo sapiens OX=9606 GN=HDLBP PE=1 SV=2 8.8 2940.4 - 2.20E+06 - - - -0.7215 - 2.704 0.498 - 480.7 1 2 0 -0.001 12 0 0 0 3.68E+07 2.40E+07 - - - 6.8492 0.965 221125_WJC_METTL3_EV_vs_WT_F03.16522.16522.2 0.000855 20-Jul R.AQVQEFC[160.03]DYGT.K "sp|Q86U44|MTA70_HUMAN,tr|H0YFV6|H0YFV6_HUMAN" 2 1316.5343 - 31873 16522 2 1316.534707 659.2744 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 3.67 2940.6 - 1.24E+06 - - - 0.2962 - 1.562 0.355 - 169.9 1 1 0 0.0004 11 0 0 0 - - - - - 2.8694 0.9997 221125_WJC_METTL3_EV_vs_WT_F03.16525.16525.2 0.0129 18-Oct K.IDIIPNPQER.T "sp|P08238|HS90B_HUMAN,sp|Q58FF7|H90B3_HUMAN" 2 1193.6404 0.98 31875 16525 2 1193.640936 597.8275 Heat shock protein HSP 90-beta OS=Homo sapiens OX=9606 GN=HSP90AB1 PE=1 SV=4 4.37 2941 - 7.33E+06 - - - 0.418 - 2.098 0.348 - 319.6 1 2 0 0.0005 10 0 0 0 2.93E+08 3.00E+08 - - - 3.6795 0.9999 221125_WJC_METTL3_EV_vs_WT_F03.16527.16527.2 2.73E-06 14/22 R.TVIIEQSWGSPK[136.11].V "sp|P10809|CH60_HUMAN,tr|C9JL25|C9JL25_HUMAN,tr|A0A7I2V2X6|A0A7I2V2X6_HUMAN,tr|A0A7I2YQK6|A0A7I2YQK6_HUMAN,tr|A0A7I2V599|A0A7I2V599_HUMAN,tr|E7EXB4|E7EXB4_HUMAN,tr|C9JL19|C9JL19_HUMAN,tr|A0A7I2YQ71|A0A7I2YQ71_HUMAN,tr|E7ESH4|E7ESH4_HUMAN,tr|A0A7I2V5M1|A0A7I2V5M1_HUMAN,tr|A0A7I2V5K3|A0A7I2V5K3_HUMAN,tr|A0A7I2V369|A0A7I2V369_HUMAN,tr|C9JCQ4|C9JCQ4_HUMAN" 13 1351.7227 1.27 31876 16527 2 1351.724059 676.8686 "60 kDa heat shock protein, mitochondrial OS=Homo sapiens OX=9606 GN=HSPD1 PE=1 SV=2" 5.66 2941.2 - 8.75E+06 - - - 0.9935 - 2.746 0.522 - 639.1 1 2 0 0.0013 12 0 0 0 1.62E+10 1.28E+10 - - - 5.5539 0.9999 221125_WJC_METTL3_EV_vs_WT_F03.16528.16528.2 1.64E-05 13/22 R.TVIIEQSWGSPK.V "sp|P10809|CH60_HUMAN,tr|C9JL25|C9JL25_HUMAN,tr|A0A7I2V2X6|A0A7I2V2X6_HUMAN,tr|A0A7I2YQK6|A0A7I2YQK6_HUMAN,tr|A0A7I2V599|A0A7I2V599_HUMAN,tr|E7EXB4|E7EXB4_HUMAN,tr|C9JL19|C9JL19_HUMAN,tr|A0A7I2YQ71|A0A7I2YQ71_HUMAN,tr|E7ESH4|E7ESH4_HUMAN,tr|A0A7I2V5M1|A0A7I2V5M1_HUMAN,tr|A0A7I2V5K3|A0A7I2V5K3_HUMAN,tr|A0A7I2V369|A0A7I2V369_HUMAN,tr|C9JCQ4|C9JCQ4_HUMAN" 13 1343.7085 1.27 31877 16528 2 1343.707971 672.8615 "60 kDa heat shock protein, mitochondrial OS=Homo sapiens OX=9606 GN=HSPD1 PE=1 SV=2" 5.66 2941.2 - 9.37E+06 - - - -0.4056 - 2.688 0.498 - 565.6 1 2 0 -0.0005 12 0 0 0 1.62E+10 1.28E+10 - - - 5.3208 0.9948 221125_WJC_METTL3_EV_vs_WT_F03.16529.16529.3 0.1 Oct-36 K.MIFDVESMK[136.11]K[136.11].A sp|P09874|PARP1_HUMAN 1 1242.6323 0.49 31878 16529 3 1242.631323 415.218 Poly [ADP-ribose] polymerase 1 OS=Homo sapiens OX=9606 GN=PARP1 PE=1 SV=4 5.82 2941.3 - 6.93E+06 - - - -0.7999 - 1.633 0.201 - 91 1 2 0 -0.001 10 0 0 0 6.73E+07 1.36E+08 - - - 2.2129 0.9999 221125_WJC_METTL3_EV_vs_WT_F03.16530.16530.2 0.0118 16-Dec K.HFLPEMLSK.V "sp|P78344|IF4G2_HUMAN,tr|E9PKF8|E9PKF8_HUMAN,tr|H0Y3P2|H0Y3P2_HUMAN,tr|D3DQV9|D3DQV9_HUMAN" 4 1100.5689 2.09 31879 16530 2 1100.568166 551.2917 Eukaryotic translation initiation factor 4 gamma 2 OS=Homo sapiens OX=9606 GN=EIF4G2 PE=1 SV=1 6.75 2941.3 - 5.21E+06 - - - -0.6233 - 2.364 0.433 - 544.1 1 2 0 -0.0007 9 0 0 0 2.07E+08 9.93E+07 - - - 4.728 1 221125_WJC_METTL3_EV_vs_WT_F03.16531.16531.3 3.26E-06 Dec-48 R.MSVDAVEIETLR[166.11]K[136.11].T "sp|P78347|GTF2I_HUMAN,tr|A0A494C1K3|A0A494C1K3_HUMAN" 2 1507.8035 1.59 31880 16531 3 1507.801935 503.6084 General transcription factor II-I OS=Homo sapiens OX=9606 GN=GTF2I PE=1 SV=2 4.68 2941.4 - 3.16E+06 - - - -1.0373 - 2.55 0.463 - 230.7 1 2 0 -0.0016 13 0 0 0 5.13E+08 3.22E+08 - - - 6.2396 0.9999 221125_WJC_METTL3_EV_vs_WT_F03.16532.16532.3 0.000418 Nov-36 K.LFEHYYQELK[136.11].L "sp|Q08J23|NSUN2_HUMAN,tr|A0A140T9Y7|A0A140T9Y7_HUMAN" 2 1376.6856 0.98 31881 16532 3 1376.685767 459.9025 RNA cytosine C(5)-methyltransferase NSUN2 OS=Homo sapiens OX=9606 GN=NSUN2 PE=1 SV=2 5.4 2941.5 - 1.06E+06 - - - 0.1191 - 2.129 0.41 - 167.7 1 2 0 0.0002 10 0 0 0 8.82E+07 8.96E+07 - - - 5.3179 0.892 221125_WJC_METTL3_EV_vs_WT_F03.16533.16533.3 0.3 Oct-52 R.LTSNPLASHDYILK[136.11].L sp|Q969X5|ERGI1_HUMAN 1 1578.8497 0.78 31882 16533 3 1578.851697 527.2905 Endoplasmic reticulum-Golgi intermediate compartment protein 1 OS=Homo sapiens OX=9606 GN=ERGIC1 PE=1 SV=1 6.74 2941.6 - 770786 - - - 1.2598 - 1.933 0.021 - 119.6 1 2 0 0.002 14 0 0 0 1.21E+07 1.54E+07 - - - 0.5251 0.9811 221125_WJC_METTL3_EV_vs_WT_F03.16534.16534.3 0.0611 Sep-44 K.LGLK[136.11]PLEVNAIK[136.11].K "sp|O43290|SNUT1_HUMAN,tr|E9PQI8|E9PQI8_HUMAN" 2 1309.8304 2.81 31883 16534 3 1309.829935 437.6174 U4\U6.U5 tri-snRNP-associated protein 1 OS=Homo sapiens OX=9606 GN=SART1 PE=1 SV=1 8.59 2941.8 - 515353 - - - -0.3726 - 1.384 0.178 - 52 1 2 0 -0.0005 12 0 0 0 1.81E+07 6.42E+06 - - - 1.4252 0.9989 221125_WJC_METTL3_EV_vs_WT_F03.16539.16539.3 0.00806 Nov-52 K.TLAEHQQLIPLVEK.A "sp|Q9Y5K5|UCHL5_HUMAN,tr|H0Y4K0|H0Y4K0_HUMAN,tr|H0Y4E0|H0Y4E0_HUMAN,tr|Q5LJA9|Q5LJA9_HUMAN,tr|H0Y636|H0Y636_HUMAN,tr|H0Y6Y4|H0Y6Y4_HUMAN,tr|Q5LJA5|Q5LJA5_HUMAN" 7 1617.909 1.86 31886 16539 3 1617.909885 540.3103 Ubiquitin carboxyl-terminal hydrolase isozyme L5 OS=Homo sapiens OX=9606 GN=UCHL5 PE=1 SV=3 5.37 2942.3 - 4.03E+06 - - - 0.5427 - 1.75 0.289 - 70.4 1 2 0 0.0009 14 0 0 0 1.76E+08 9.46E+07 - - - 3.249 1 221125_WJC_METTL3_EV_vs_WT_F03.16540.16540.3 0.000156 17/40 R.TPLHEIALSIK.L sp|Q08211|DHX9_HUMAN 1 1220.7129 6.77 31887 16540 3 1220.712009 407.9116 ATP-dependent RNA helicase A OS=Homo sapiens OX=9606 GN=DHX9 PE=1 SV=4 6.41 2942.4 - 7.10E+06 - - - -0.7078 - 3.115 0.493 - 372.4 1 2 0 -0.0009 11 0 0 0 9.76E+08 1.44E+08 - - - 7.2641 0.9996 221125_WJC_METTL3_EV_vs_WT_F03.16541.16541.2 0.000109 16-Oct K.VPEWVDTVK.L "sp|P39019|RS19_HUMAN,tr|M0R140|M0R140_HUMAN,tr|M0R2L9|M0R2L9_HUMAN,tr|M0QYF7|M0QYF7_HUMAN" 4 1071.5601 1 31888 16541 2 1071.558092 536.7873 40S ribosomal protein S19 OS=Homo sapiens OX=9606 GN=RPS19 PE=1 SV=2 4.37 2942.4 - 2.58E+06 - - - -1.8375 - 1.841 0.432 - 318.9 1 2 0 -0.002 9 0 0 0 3.94E+07 3.93E+07 - - - 3.9968 0.9998 221125_WJC_METTL3_EV_vs_WT_F03.16543.16543.3 0.000247 14/48 K.LDNVLLDSEGHIK[136.11].L sp|P41743|KPCI_HUMAN 1 1459.7762 0.79 31890 16543 3 1459.775325 487.5993 Protein kinase C iota type OS=Homo sapiens OX=9606 GN=PRKCI PE=1 SV=2 4.54 2942.5 - 2.16E+06 - - - -0.6056 - 2.179 0.339 - 172.6 1 2 0 -0.0009 13 0 0 0 2.45E+07 3.11E+07 - - - 4.431 0.9993 221125_WJC_METTL3_EV_vs_WT_F03.16544.16544.3 0.00687 Sep-36 K.LFEHYYQELK.L "sp|Q08J23|NSUN2_HUMAN,tr|A0A140T9Y7|A0A140T9Y7_HUMAN" 2 1368.6714 0.98 31891 16544 3 1368.669505 457.2311 RNA cytosine C(5)-methyltransferase NSUN2 OS=Homo sapiens OX=9606 GN=NSUN2 PE=1 SV=2 5.4 2942.6 - 1.81E+06 - - - -1.3867 - 1.876 0.298 - 106.7 1 2 0 -0.0019 10 0 0 0 8.80E+07 8.96E+07 - - - 3.6992 0.9998 221125_WJC_METTL3_EV_vs_WT_F03.16545.16545.2 0.0166 22-Dec R.GNEVLYNGFTGR.K "sp|P30876|RPB2_HUMAN,tr|C9J4M6|C9J4M6_HUMAN,tr|C9J2Y9|C9J2Y9_HUMAN" 3 1325.6364 1.02 31892 16545 2 1325.636314 663.8255 DNA-directed RNA polymerase II subunit RPB2 OS=Homo sapiens OX=9606 GN=POLR2B PE=1 SV=1 6 2942.7 - 1.63E+06 - - - -0.0754 - 2.329 0.419 - 636.2 1 2 0 -0.0001 12 0 0 0 2.76E+07 2.71E+07 - - - 4.3602 1 221125_WJC_METTL3_EV_vs_WT_F03.16547.16547.2 1.06E-09 19/30 K.VTADVTSAVMGNPVTR.E "sp|Q6P3W7|SCYL2_HUMAN,tr|F8VSC5|F8VSC5_HUMAN,tr|A0A0U1RQQ9|A0A0U1RQQ9_HUMAN" 3 1616.8192 2.17 31894 16547 2 1616.817789 809.4169 SCY1-like protein 2 OS=Homo sapiens OX=9606 GN=SCYL2 PE=1 SV=1 5.81 2943 - 881168 - - - -0.8764 - 3.536 0.621 - 1325.3 1 2 0 -0.0014 16 0 0 0 9.92E+07 4.57E+07 - - - 6.7324 0.9998 221125_WJC_METTL3_EV_vs_WT_F03.16548.16548.2 2.55E-05 13/22 R.LNSSDPSLIGLK[136.11].Q "sp|Q9UHI6|DDX20_HUMAN,tr|A0A7P0T8G7|A0A7P0T8G7_HUMAN,tr|A0A7P0TB94|A0A7P0TB94_HUMAN,tr|A0A7P0T9T8|A0A7P0T9T8_HUMAN" 4 1250.6962 0.96 31895 16548 2 1250.697781 626.3554 Probable ATP-dependent RNA helicase DDX20 OS=Homo sapiens OX=9606 GN=DDX20 PE=1 SV=2 5.84 2943.1 - 783392 - - - 1.2905 - 2.633 0.451 - 613.6 1 2 0 0.0016 12 0 0 0 1.67E+07 1.75E+07 - - - 4.9189 0.7916 221125_WJC_METTL3_EV_vs_WT_F03.16549.16549.2 3.44 14-Jun K.YYYIPQYK.N "sp|Q8N183|NDUF2_HUMAN,tr|H0YA50|H0YA50_HUMAN,tr|A0A7I2V3X5|A0A7I2V3X5_HUMAN,tr|D6RA56|D6RA56_HUMAN,tr|A0A7I2YQX2|A0A7I2YQX2_HUMAN,tr|A0A7I2V4Z7|A0A7I2V4Z7_HUMAN" 6 1136.5542 7.12 31896 16549 2 1136.558151 569.2844 NADH dehydrogenase [ubiquinone] 1 alpha subcomplex assembly factor 2 OS=Homo sapiens OX=9606 GN=NDUFAF2 PE=1 SV=1 8.38 2943.2 - 558197 - - - 3.4349 - 0.934 0.118 - 98.7 1 2 0 0.0039 8 0 0 0 6.75E+06 9.47E+05 - - - -0.2946 0.9997 221125_WJC_METTL3_EV_vs_WT_F03.16550.16550.2 0.000418 24-Oct R.WAVVSGATDGIGK.A "sp|Q3SXM5|HSDL1_HUMAN,tr|H3BQI7|H3BQI7_HUMAN,tr|H3BT52|H3BT52_HUMAN" 3 1259.651 0.74 31897 16550 2 1259.650564 630.8328 Inactive hydroxysteroid dehydrogenase-like protein 1 OS=Homo sapiens OX=9606 GN=HSDL1 PE=1 SV=3 5.84 2943.4 - 473230 - - - -0.3469 - 2.081 0.361 - 195.2 1 2 0 -0.0004 13 0 0 0 4.33E+06 5.85E+06 - - - 3.5881 0.9999 221125_WJC_METTL3_EV_vs_WT_F03.16553.16553.3 9.73E-06 13/40 R.TLKIPAMTIAK.N "sp|P10809|CH60_HUMAN,tr|A0A7I2V2X6|A0A7I2V2X6_HUMAN,tr|A0A7I2YQK6|A0A7I2YQK6_HUMAN,tr|A0A7I2V599|A0A7I2V599_HUMAN" 4 1185.7155 1.17 31899 16553 3 1185.715311 396.2458 "60 kDa heat shock protein, mitochondrial OS=Homo sapiens OX=9606 GN=HSPD1 PE=1 SV=2" 10 2943.7 - 375102 - - - -0.1729 - 2.468 0.507 - 168.7 1 2 1 -0.0002 11 0 0 0 1.73E+08 1.48E+08 - - - 6.7589 0.9872 221125_WJC_METTL3_EV_vs_WT_F03.16555.16555.2 0.00944 16-Sep L.NSIIDVYHK.Y sp|P05109|S10A8_HUMAN 1 1087.5662 999 31900 16555 2 1087.566166 544.7904 Protein S100-A8 OS=Homo sapiens OX=9606 GN=S100A8 PE=1 SV=1 6.74 2943.9 - 5.91E+06 - - - -0.0395 - 2.077 0.382 - 369.6 1 1 0 0 9 0 0 0 6.81E+07 0.00E+00 - - - 3.977 0.9992 221125_WJC_METTL3_EV_vs_WT_F03.16556.16556.3 0.00713 Aug-32 R.R[166.11]LNVWDLSK[136.11].L "sp|Q09028|RBBP4_HUMAN,sp|Q16576|RBBP7_HUMAN,tr|H0YCT5|H0YCT5_HUMAN,tr|H0YDK2|H0YDK2_HUMAN,tr|Q5JP02|Q5JP02_HUMAN,tr|H0YEU5|H0YEU5_HUMAN,tr|H0YF10|H0YF10_HUMAN,tr|E9PC52|E9PC52_HUMAN" 8 1147.6469 0.001 31901 16556 3 1147.645507 383.5562 Histone-binding protein RBBP4 OS=Homo sapiens OX=9606 GN=RBBP4 PE=1 SV=3 8.75 2944 - 4.41E+06 - - - -1.1815 - 1.677 0.308 - 134.5 1 2 0 -0.0014 9 0 0 0 0.00E+00 4.74E+07 - - - 3.5317 0.9963 221125_WJC_METTL3_EV_vs_WT_F03.16557.16557.2 0.000306 18-Oct K.DSNFAGDLVR.N "sp|Q86XP3|DDX42_HUMAN,tr|A0A0A0MSJ0|A0A0A0MSJ0_HUMAN" 2 1092.52 0.74 31902 16557 2 1092.513932 547.2673 ATP-dependent RNA helicase DDX42 OS=Homo sapiens OX=9606 GN=DDX42 PE=1 SV=1 4.21 2944 - 3.61E+06 - - - -5.5422 - 2.297 0.454 - 481.2 1 2 0 -0.0061 10 0 0 0 4.04E+07 5.45E+07 - - - 4.7136 0.9987 221125_WJC_METTL3_EV_vs_WT_F03.16558.16558.3 1.13E-05 14/40 R.LAYKDLEIQMK.K "sp|Q9NP61|ARFG3_HUMAN,tr|H0Y6A0|H0Y6A0_HUMAN" 2 1350.7217 1.3 31903 16558 3 1350.716837 451.2479 ADP-ribosylation factor GTPase-activating protein 3 OS=Homo sapiens OX=9606 GN=ARFGAP3 PE=1 SV=1 6.07 2944.2 - 1.53E+06 - - - -3.6181 - 2.545 0.426 - 208.7 1 2 1 -0.0049 11 0 0 0 1.42E+07 1.09E+07 - - - 5.9418 1 221125_WJC_METTL3_EV_vs_WT_F03.16559.16559.3 6.96E-06 17/52 R.LTSNPLASHDYILK.L sp|Q969X5|ERGI1_HUMAN 1 1570.8355 0.78 31904 16559 3 1570.83485 524.6191 Endoplasmic reticulum-Golgi intermediate compartment protein 1 OS=Homo sapiens OX=9606 GN=ERGIC1 PE=1 SV=1 6.74 2944.3 - 1.20E+06 - - - -0.4189 - 2.836 0.451 - 438.8 1 2 0 -0.0007 14 0 0 0 1.21E+07 1.54E+07 - - - 6.3382 1 221125_WJC_METTL3_EV_vs_WT_F03.16560.16560.2 2.63E-08 16/26 K.LLSELDQQSTEMPR[166.11].T "sp|O95793|STAU1_HUMAN,tr|Q5JW30|Q5JW30_HUMAN" 2 1655.8064 2.25 31905 16560 2 1655.805242 828.9105 Double-stranded RNA-binding protein Staufen homolog 1 OS=Homo sapiens OX=9606 GN=STAU1 PE=1 SV=2 4.14 2944.4 - 1.10E+06 - - - -0.703 - 3.143 0.583 - 1019.1 1 2 0 -0.0012 14 0 0 0 9.97E+07 4.44E+07 - - - 6.2204 1 221125_WJC_METTL3_EV_vs_WT_F03.16561.16561.2 6.62E-09 18/28 R.FVGVNASDINYSAGR[166.11].Y sp|Q8N4Q0|PTGR3_HUMAN 1 1578.7666 1.52 31906 16561 2 1578.76474 790.3906 Prostaglandin reductase 3 OS=Homo sapiens OX=9606 GN=ZADH2 PE=1 SV=1 5.84 2944.6 - 956461 - - - -1.1718 - 3.115 0.618 - 1067.3 1 2 0 -0.0019 15 0 0 0 6.70E+07 4.40E+07 - - - 6.3984 0.998 221125_WJC_METTL3_EV_vs_WT_F03.16562.16562.2 0.311 12-Jul R.DVQEIFR.M "sp|Q13838|DX39B_HUMAN,sp|O00148|DX39A_HUMAN,tr|A0A140TA18|A0A140TA18_HUMAN,tr|F6UJC5|F6UJC5_HUMAN,tr|F6TRA5|F6TRA5_HUMAN,tr|F6WLT2|F6WLT2_HUMAN,tr|Q5STU3|Q5STU3_HUMAN,tr|A0A140T973|A0A140T973_HUMAN,tr|A0A140T9X9|A0A140T9X9_HUMAN,tr|A0A140T996|A0A140T996_HUMAN,tr|A0A140T9L4|A0A140T9L4_HUMAN,tr|A0A0G2JJZ9|A0A0G2JJZ9_HUMAN,tr|A0A140T9K1|A0A140T9K1_HUMAN,tr|K7EQN7|K7EQN7_HUMAN,tr|A0A140T9X3|A0A140T9X3_HUMAN,tr|H0YCC6|H0YCC6_HUMAN,tr|F6S4E6|F6S4E6_HUMAN,tr|A0A0A0MT12|A0A0A0MT12_HUMAN" 18 905.4607 1.11 31907 16562 2 905.460347 453.7376 Spliceosome RNA helicase DDX39B OS=Homo sapiens OX=9606 GN=DDX39B PE=1 SV=1 4.37 2944.7 - 915630 - - - -0.3689 - 1.392 0.23 - 201.9 1 2 0 -0.0003 7 0 0 0 1.47E+07 1.32E+07 - - - 1.7876 0.9997 221125_WJC_METTL3_EV_vs_WT_F03.16563.16563.3 0.00117 13/44 K.LGLKPLEVNAIK.K "sp|O43290|SNUT1_HUMAN,tr|E9PQI8|E9PQI8_HUMAN" 2 1293.802 2.81 31908 16563 3 1293.799766 432.2746 U4\U6.U5 tri-snRNP-associated protein 1 OS=Homo sapiens OX=9606 GN=SART1 PE=1 SV=1 8.59 2944.8 - 849115 - - - -1.7445 - 2.008 0.379 - 134.6 1 2 0 -0.0023 12 0 0 0 1.81E+07 6.42E+06 - - - 4.6972 0.9998 221125_WJC_METTL3_EV_vs_WT_F03.16564.16564.3 4.45E-07 15/44 R.LLREYQELMNTK.L "sp|P13647|K2C5_HUMAN,tr|H0YI76|H0YI76_HUMAN" 2 1536.797 999 31909 16564 3 1536.797308 513.2729 "Keratin, type II cytoskeletal 5 OS=Homo sapiens OX=9606 GN=KRT5 PE=1 SV=3" 6.14 2944.9 - 842467 - - - 0.1913 - 2.883 0.44 - 483.1 1 2 1 0.0003 12 0 0 0 1.24E+07 0.00E+00 - - - 6.3804 0.9998 221125_WJC_METTL3_EV_vs_WT_F03.16566.16566.2 7.04E-05 18-Sep K.GDDLSTAILK[136.11].Q "sp|P55072|TERA_HUMAN,tr|A0A7P0Z4C6|A0A7P0Z4C6_HUMAN,tr|A0A7I2V2Y2|A0A7I2V2Y2_HUMAN,tr|A0A7P0T8Q5|A0A7P0T8Q5_HUMAN,tr|A0A7P0TAW3|A0A7P0TAW3_HUMAN,tr|A0A7P0Z4D1|A0A7P0Z4D1_HUMAN,tr|A0A7I2YQJ0|A0A7I2YQJ0_HUMAN,tr|A0A7I2V540|A0A7I2V540_HUMAN,tr|A0A7P0TAQ1|A0A7P0TAQ1_HUMAN,tr|A0A7I2V5G8|A0A7I2V5G8_HUMAN,tr|A0A7P0TBK7|A0A7P0TBK7_HUMAN" 11 1039.5641 1.05 31911 16566 2 1039.562741 520.7893 Transitional endoplasmic reticulum ATPase OS=Homo sapiens OX=9606 GN=VCP PE=1 SV=4 4.21 2945.1 - 740600 - - - -1.2977 - 2.081 0.432 - 229.3 1 2 0 -0.0014 10 0 0 0 8.51E+06 8.07E+06 - - - 4.2769 0.9998 221125_WJC_METTL3_EV_vs_WT_F03.16569.16569.2 0.000593 18-Oct R.VATWFNQPAR[166.11].K "sp|P26373|RL13_HUMAN,tr|H3BTH3|H3BTH3_HUMAN,tr|J3QSB4|J3QSB4_HUMAN" 3 1198.6123 1.06 31912 16569 2 1198.613101 600.3134 60S ribosomal protein L13 OS=Homo sapiens OX=9606 GN=RPL13 PE=1 SV=4 9.72 2945.5 - 2.66E+06 - - - 0.7 - 2.14 0.408 - 459 1 2 0 0.0008 10 0 0 0 1.82E+08 1.71E+08 - - - 4.1779 1 221125_WJC_METTL3_EV_vs_WT_F03.16570.16570.2 9.19E-10 19/28 R.FVGVNASDINYSAGR.Y sp|Q8N4Q0|PTGR3_HUMAN 1 1568.7583 1.52 31913 16570 2 1568.757846 785.3864 Prostaglandin reductase 3 OS=Homo sapiens OX=9606 GN=ZADH2 PE=1 SV=1 5.84 2945.7 - 3.00E+06 - - - -0.3021 - 3.223 0.668 - 1230.3 1 2 0 -0.0005 15 0 0 0 6.70E+07 4.40E+07 - - - 6.852 0.9999 221125_WJC_METTL3_EV_vs_WT_F03.16571.16571.3 0.000502 13/52 K.TLAEHQQLIPLVEK[136.11].A "sp|Q9Y5K5|UCHL5_HUMAN,tr|H0Y4K0|H0Y4K0_HUMAN,tr|H0Y4E0|H0Y4E0_HUMAN,tr|Q5LJA9|Q5LJA9_HUMAN,tr|H0Y636|H0Y636_HUMAN,tr|H0Y6Y4|H0Y6Y4_HUMAN,tr|Q5LJA5|Q5LJA5_HUMAN" 7 1625.9232 1.86 31914 16571 3 1625.920676 542.9817 Ubiquitin carboxyl-terminal hydrolase isozyme L5 OS=Homo sapiens OX=9606 GN=UCHL5 PE=1 SV=3 5.37 2945.7 - 6.31E+06 - - - -1.5567 - 2.378 0.406 - 135.1 1 2 0 -0.0025 14 0 0 0 1.76E+08 9.46E+07 - - - 5.3679 1 221125_WJC_METTL3_EV_vs_WT_F03.16572.16572.2 5.26E-07 13/16 K.HFLPEMLSK[136.11].V "sp|P78344|IF4G2_HUMAN,tr|E9PKF8|E9PKF8_HUMAN,tr|H0Y3P2|H0Y3P2_HUMAN,tr|D3DQV9|D3DQV9_HUMAN" 4 1108.5831 1.66 31915 16572 2 1108.580828 555.2988 Eukaryotic translation initiation factor 4 gamma 2 OS=Homo sapiens OX=9606 GN=EIF4G2 PE=1 SV=1 6.75 2945.7 - 5.36E+06 - - - -2.0062 - 2.389 0.586 - 661.4 1 2 0 -0.0022 9 0 0 0 9.21E+07 5.53E+07 - - - 5.888 0.998 221125_WJC_METTL3_EV_vs_WT_F03.16573.16573.2 0.000551 18-Sep R.VATWFNQPAR.K "sp|P26373|RL13_HUMAN,tr|H3BTH3|H3BTH3_HUMAN,tr|J3QSB4|J3QSB4_HUMAN" 3 1188.604 1.04 31916 16573 2 1188.599636 595.3093 60S ribosomal protein L13 OS=Homo sapiens OX=9606 GN=RPL13 PE=1 SV=4 9.72 2945.8 - 2.29E+06 - - - -3.6648 - 1.859 0.396 - 344.2 1 2 0 -0.0044 10 0 0 0 1.79E+08 1.71E+08 - - - 3.6952 0.9998 221125_WJC_METTL3_EV_vs_WT_F03.16575.16575.2 4.58E-06 22-Dec R.GNEVLYNGFTGR[166.11].K "sp|P30876|RPB2_HUMAN,tr|C9J4M6|C9J4M6_HUMAN,tr|C9J2Y9|C9J2Y9_HUMAN" 3 1335.6447 1.02 31918 16575 2 1335.646998 668.8296 DNA-directed RNA polymerase II subunit RPB2 OS=Homo sapiens OX=9606 GN=POLR2B PE=1 SV=1 6 2946.1 - 1.05E+06 - - - 1.7325 - 2.354 0.547 - 697.4 1 2 0 0.0023 12 0 0 0 2.76E+07 2.71E+07 - - - 5.333 0.9995 221125_WJC_METTL3_EV_vs_WT_F03.16578.16578.2 9.24E-05 18-Oct K.GDDLSTAILK.Q "sp|P55072|TERA_HUMAN,tr|A0A7P0Z4C6|A0A7P0Z4C6_HUMAN,tr|A0A7I2V2Y2|A0A7I2V2Y2_HUMAN,tr|A0A7P0T8Q5|A0A7P0T8Q5_HUMAN,tr|A0A7P0TAW3|A0A7P0TAW3_HUMAN,tr|A0A7P0Z4D1|A0A7P0Z4D1_HUMAN,tr|A0A7I2YQJ0|A0A7I2YQJ0_HUMAN,tr|A0A7I2V540|A0A7I2V540_HUMAN,tr|A0A7P0TAQ1|A0A7P0TAQ1_HUMAN,tr|A0A7I2V5G8|A0A7I2V5G8_HUMAN,tr|A0A7P0TBK7|A0A7P0TBK7_HUMAN" 11 1031.5499 1.05 31921 16578 2 1031.547281 516.7822 Transitional endoplasmic reticulum ATPase OS=Homo sapiens OX=9606 GN=VCP PE=1 SV=4 4.21 2946.5 - 860735 - - - -2.5292 - 2.38 0.396 - 259.2 1 2 0 -0.0026 10 0 0 0 8.51E+06 8.07E+06 - - - 4.3854 0.9997 221125_WJC_METTL3_EV_vs_WT_F03.16581.16581.2 0.00037 18-Dec K.LFEHYYQELK.L "sp|Q08J23|NSUN2_HUMAN,tr|A0A140T9Y7|A0A140T9Y7_HUMAN" 2 1368.6714 0.95 31924 16581 2 1368.670158 685.343 RNA cytosine C(5)-methyltransferase NSUN2 OS=Homo sapiens OX=9606 GN=NSUN2 PE=1 SV=2 5.4 2946.9 - 528770 - - - -0.9096 - 2.055 0.382 - 334.5 1 2 0 -0.0012 10 0 0 0 1.16E+07 1.21E+07 - - - 3.8726 1 221125_WJC_METTL3_EV_vs_WT_F03.16582.16582.2 7.18E-10 13/26 R.SEQEDEVLLVSSSR[166.11].Y "sp|Q9NZJ9|NUDT4_HUMAN,sp|A0A024RBG1|NUD4B_HUMAN" 2 1586.7663 9.23 31925 16582 2 1586.765424 794.3904 Diphosphoinositol polyphosphate phosphohydrolase 2 OS=Homo sapiens OX=9606 GN=NUDT4 PE=1 SV=2 4 2947 - 527686 - - - -0.5615 - 2.947 0.63 - 651.4 1 2 0 -0.0009 14 0 0 0 3.84E+07 4.16E+06 - - - 6.4061 0.9997 221125_WJC_METTL3_EV_vs_WT_F03.16584.16584.3 0.000391 Oct-40 K.ALNSIIDVYHK.Y sp|P05109|S10A8_HUMAN 1 1271.6874 4696.76 31926 16584 3 1271.685143 424.9031 Protein S100-A8 OS=Homo sapiens OX=9606 GN=S100A8 PE=1 SV=1 6.79 2947.2 - 1.05E+08 - - - -1.7646 - 1.938 0.377 - 132.5 1 2 0 -0.0022 11 0 0 0 1.25E+09 2.66E+05 - - - 4.6222 0.769 221125_WJC_METTL3_EV_vs_WT_F03.16585.16585.3 0.0249 Oct-36 P.SVFLFPPKPK.D "sp|P01859|IGHG2_HUMAN,sp|P01860|IGHG3_HUMAN,sp|P01861|IGHG4_HUMAN,sp|P01857|IGHG1_HUMAN,tr|A0A4W9A917|A0A4W9A917_HUMAN,tr|A0A286YES1|A0A286YES1_HUMAN,tr|A0A0A0MS08|A0A0A0MS08_HUMAN,tr|A0A286YFJ8|A0A286YFJ8_HUMAN,tr|A0A0A0MS07|A0A0A0MS07_HUMAN,tr|A0A286YEY4|A0A286YEY4_HUMAN" 10 1158.6801 11.83 31927 16585 3 1158.678904 387.234 Immunoglobulin heavy constant gamma 2 OS=Homo sapiens OX=9606 GN=IGHG2 PE=1 SV=2 10 2947.3 - 1.15E+06 - - - -1.0469 - 1.466 0.265 - 124.4 1 1 0 -0.0012 10 0 0 0 9.91E+06 8.38E+05 - - - 2.6113 1 221125_WJC_METTL3_EV_vs_WT_F03.16586.16586.3 1.91E-05 15/48 R.MSVDAVEIETLRK.T "sp|P78347|GTF2I_HUMAN,tr|A0A494C1K3|A0A494C1K3_HUMAN" 2 1489.781 1.61 31928 16586 3 1489.777629 497.601 General transcription factor II-I OS=Homo sapiens OX=9606 GN=GTF2I PE=1 SV=2 4.68 2947.4 - 4.33E+07 - - - -2.2822 - 2.835 0.501 - 371.1 1 2 0 -0.0034 13 0 0 0 5.23E+08 3.25E+08 - - - 6.95 0.9997 221125_WJC_METTL3_EV_vs_WT_F03.16589.16589.2 9.94E-06 16/26 R.IAEFTTNLTEEEEK[136.11].S sp|P35579|MYH9_HUMAN 1 1660.7923 1.08 31931 16589 2 1660.788442 831.4034 Myosin-9 OS=Homo sapiens OX=9606 GN=MYH9 PE=1 SV=4 3.98 2947.6 - 3.18E+06 - - - -2.3302 - 3.186 0.466 - 860.5 1 2 0 -0.0039 14 0 0 0 2.50E+08 2.31E+08 - - - 5.3895 0.9993 221125_WJC_METTL3_EV_vs_WT_F03.16595.16595.2 0.049 16-Oct R.KLFIGMISK.K "sp|Q92879|CELF1_HUMAN,tr|G5EA30|G5EA30_HUMAN" 2 1035.6151 1.26 31937 16595 2 1035.613246 518.8148 CUGBP Elav-like family member 1 OS=Homo sapiens OX=9606 GN=CELF1 PE=1 SV=2 10 2948.2 - 905591 - - - -1.7651 - 2.091 0.294 - 360.1 1 2 0 -0.0018 9 0 0 0 9.43E+06 7.48E+06 - - - 3.3459 0.936 221125_WJC_METTL3_EV_vs_WT_F03.16598.16598.2 0.0119 18-Dec R.YPVNSVNILK[136.11].A "sp|P17987|TCPA_HUMAN,tr|E7EQR6|E7EQR6_HUMAN,tr|E7ERF2|E7ERF2_HUMAN" 3 1153.6587 1.25 31939 16598 2 1153.653623 577.8366 T-complex protein 1 subunit alpha OS=Homo sapiens OX=9606 GN=TCP1 PE=1 SV=1 8.59 2948.6 - 2.90E+06 - - - -4.3652 - 1.622 0.086 - 196.9 1 2 0 -0.005 10 0 0 0 1.22E+08 9.70E+07 - - - 1.0247 1 221125_WJC_METTL3_EV_vs_WT_F03.16600.16600.2 0.000137 13/26 R.IAEFTTNLTEEEEK.S sp|P35579|MYH9_HUMAN 1 1652.7781 1.08 31940 16600 2 1652.774654 827.3963 Myosin-9 OS=Homo sapiens OX=9606 GN=MYH9 PE=1 SV=4 3.98 2948.8 - 7.15E+06 - - - -2.0922 - 2.97 0.541 - 504.9 1 2 0 -0.0035 14 0 0 0 2.50E+08 2.31E+08 - - - 5.7674 1 221125_WJC_METTL3_EV_vs_WT_F03.16601.16601.2 2.13E-07 17/30 K.VTADVTSAVMGNPVTR[166.11].E "sp|Q6P3W7|SCYL2_HUMAN,tr|F8VSC5|F8VSC5_HUMAN,tr|A0A0U1RQQ9|A0A0U1RQQ9_HUMAN" 3 1626.8275 2.17 31941 16601 2 1626.822513 814.421 SCY1-like protein 2 OS=Homo sapiens OX=9606 GN=SCYL2 PE=1 SV=1 5.81 2948.9 - 3.64E+06 - - - -3.0507 - 3.348 0.584 - 975.7 1 2 0 -0.005 16 0 0 0 9.92E+07 4.57E+07 - - - 6.3237 0.9963 221125_WJC_METTL3_EV_vs_WT_F03.16604.16604.2 0.0177 14-Sep R.QLLDFSQK[136.11].L "sp|O14980|XPO1_HUMAN,tr|F8WF71|F8WF71_HUMAN,tr|A0A7I2V461|A0A7I2V461_HUMAN,tr|A0A7P0Z4B7|A0A7P0Z4B7_HUMAN,tr|A0A7I2V2H0|A0A7I2V2H0_HUMAN,tr|A0A7I2YQP1|A0A7I2YQP1_HUMAN,tr|A0A7I2V3N0|A0A7I2V3N0_HUMAN,tr|A0A7I2V4A3|A0A7I2V4A3_HUMAN,tr|C9J673|C9J673_HUMAN,tr|C9JKM9|C9JKM9_HUMAN,tr|C9IYM2|C9IYM2_HUMAN,tr|A0A7I2YQV4|A0A7I2YQV4_HUMAN,tr|A0A7I2V396|A0A7I2V396_HUMAN,tr|A0A7I2YQX3|A0A7I2YQX3_HUMAN,tr|A0A7I2V2Y6|A0A7I2V2Y6_HUMAN,tr|A0A7I2V2C5|A0A7I2V2C5_HUMAN,tr|A0A7I2V3J1|A0A7I2V3J1_HUMAN,tr|A0A7I2V3P3|A0A7I2V3P3_HUMAN,tr|A0A7I2V2S3|A0A7I2V2S3_HUMAN" 19 985.5324 0.6 31944 16604 2 985.529627 493.7735 Exportin-1 OS=Homo sapiens OX=9606 GN=XPO1 PE=1 SV=1 5.84 2949 - 4.08E+06 - - - -2.8096 - 1.626 0.258 - 265.8 1 2 0 -0.0028 8 0 0 0 2.21E+07 3.71E+07 - - - 2.4118 0.9458 221125_WJC_METTL3_EV_vs_WT_F03.16606.16606.2 0.699 16-Oct E.R[166.11]VDEIIWVK[136.11].T sp|Q86U44|MTA70_HUMAN 1 1174.6829 0.25 31946 16606 2 1174.681564 588.3487 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 6.07 2949.2 - 3.71E+06 - - - -1.1492 - 2.028 0.21 - 398.2 1 1 0 -0.0014 9 0 0 0 2.01E+07 7.99E+07 - - - 2.6372 0.9997 221125_WJC_METTL3_EV_vs_WT_F03.16607.16607.3 0.00107 15/36 R.R[166.11]GDLPFVVPR[166.11].R sp|P35579|MYH9_HUMAN 1 1174.6726 0.85 31947 16607 3 1174.675065 392.5648 Myosin-9 OS=Homo sapiens OX=9606 GN=MYH9 PE=1 SV=4 9.6 2949.3 - 2.53E+06 - - - 2.1266 - 2.45 0.335 - 318.4 1 2 0 0.0025 10 0 0 0 1.75E+08 2.05E+08 - - - 4.8912 0.9998 221125_WJC_METTL3_EV_vs_WT_F03.16609.16609.3 8.93E-06 15/52 K.FPSLLTHNENMVAK.V sp|P62906|RL10A_HUMAN 1 1599.8079 1.01 31949 16609 3 1599.802556 534.2766 60S ribosomal protein L10a OS=Homo sapiens OX=9606 GN=RPL10A PE=1 SV=2 6.75 2949.6 - 1.77E+06 - - - -3.3485 - 2.684 0.426 - 216.7 1 2 0 -0.0054 14 0 0 0 5.63E+07 5.57E+07 - - - 5.9118 0.9993 221125_WJC_METTL3_EV_vs_WT_F03.16613.16613.2 8.17E-05 14/26 R.ESATADAGYAILEK.K sp|P98175|RBM10_HUMAN 1 1437.6987 2.81 31951 16613 2 1437.703904 719.8566 RNA-binding protein 10 OS=Homo sapiens OX=9606 GN=RBM10 PE=1 SV=3 4.14 2950 - 2.68E+06 - - - 3.5919 - 2.849 0.489 - 854.3 1 2 0 0.0052 14 0 0 0 1.66E+08 5.90E+07 - - - 5.2784 0.9989 221125_WJC_METTL3_EV_vs_WT_F03.16614.16614.2 1.39E-06 14/20 K.TADDPSLSLIK[136.11].Y "sp|P39656|OST48_HUMAN,tr|U3KQ84|U3KQ84_HUMAN,tr|A0A0C4DGS1|A0A0C4DGS1_HUMAN" 3 1166.6274 1.82 31952 16614 2 1166.622598 584.321 Dolichyl-diphosphooligosaccharide--protein glycosyltransferase 48 kDa subunit OS=Homo sapiens OX=9606 GN=DDOST PE=1 SV=4 4.21 2950.2 - 2.25E+06 - - - -4.1324 - 2.603 0.477 - 535.1 1 2 0 -0.0048 11 0 0 0 2.06E+08 1.13E+08 - - - 5.1506 0.9998 221125_WJC_METTL3_EV_vs_WT_F03.16615.16615.3 1.10E-05 15/36 R.RGDLPFVVPR.R sp|P35579|MYH9_HUMAN 1 1154.656 0.85 31953 16615 3 1154.651104 385.8926 Myosin-9 OS=Homo sapiens OX=9606 GN=MYH9 PE=1 SV=4 9.6 2950.3 - 2.19E+06 - - - -4.2636 - 2.357 0.51 - 325.3 1 2 0 -0.0049 10 0 0 0 1.75E+08 2.05E+08 - - - 6.7286 1 221125_WJC_METTL3_EV_vs_WT_F03.16617.16617.2 2.34E-08 15/24 K.SGSALELSVENVK.N "sp|O75688|PPM1B_HUMAN,tr|B8ZZF0|B8ZZF0_HUMAN,tr|A0A3B3IS24|A0A3B3IS24_HUMAN,tr|C9JIR6|C9JIR6_HUMAN" 4 1331.6933 3.21 31955 16617 2 1331.689511 666.8539 Protein phosphatase 1B OS=Homo sapiens OX=9606 GN=PPM1B PE=1 SV=1 4.53 2950.5 - 1.82E+06 - - - -2.8152 - 3.002 0.579 - 1102.3 1 2 0 -0.0037 13 0 0 0 2.72E+09 8.47E+08 - - - 6.1376 0.9992 221125_WJC_METTL3_EV_vs_WT_F03.16618.16618.2 0.00753 16-Sep K.YDGIILPGK.- "sp|P62913|RL11_HUMAN,tr|Q5VVC8|Q5VVC8_HUMAN" 2 974.5437 1.68 31956 16618 2 974.542001 488.2791 60S ribosomal protein L11 OS=Homo sapiens OX=9606 GN=RPL11 PE=1 SV=2 5.83 2950.6 - 1.72E+06 - - - -1.7259 - 1.748 0.329 - 235.4 1 2 0 -0.0017 9 0 0 0 1.03E+08 6.12E+07 - - - 3.0862 1 221125_WJC_METTL3_EV_vs_WT_F03.16620.16620.2 6.58E-06 15/26 R.ESATADAGYAILEK[136.11].K sp|P98175|RBM10_HUMAN 1 1445.7129 2.81 31958 16620 2 1445.706555 723.8637 RNA-binding protein 10 OS=Homo sapiens OX=9606 GN=RBM10 PE=1 SV=3 4.14 2950.9 - 1.44E+06 - - - -4.4165 - 3.098 0.558 - 900.2 1 2 0 -0.0064 14 0 0 0 1.66E+08 5.90E+07 - - - 5.998 0.9994 221125_WJC_METTL3_EV_vs_WT_F03.16625.16625.2 1.42E-06 16-Nov K.SDVEAIFSK[136.11].Y "sp|P0DMR1|HNRC4_HUMAN,sp|P07910|HNRPC_HUMAN,sp|O60812|HNRC1_HUMAN,sp|B2RXH8|HNRC2_HUMAN,sp|B7ZW38|HNRC3_HUMAN,tr|G3V251|G3V251_HUMAN,tr|B4DY08|B4DY08_HUMAN,tr|G3V575|G3V575_HUMAN,tr|B4DSU6|B4DSU6_HUMAN,tr|G3V3K6|G3V3K6_HUMAN,tr|B2R5W2|B2R5W2_HUMAN,tr|G3V4C1|G3V4C1_HUMAN,tr|A0A0G2JPF8|A0A0G2JPF8_HUMAN,tr|A0A0G2JNQ3|A0A0G2JNQ3_HUMAN,tr|G3V576|G3V576_HUMAN,tr|G3V5X6|G3V5X6_HUMAN,tr|G3V2H6|G3V2H6_HUMAN,tr|G3V4W0|G3V4W0_HUMAN,tr|G3V555|G3V555_HUMAN,tr|G3V4M8|G3V4M8_HUMAN,tr|G3V2Q1|G3V2Q1_HUMAN" 21 1002.5113 1.37 31961 16625 2 1002.508606 502.2629 Heterogeneous nuclear ribonucleoprotein C-like 4 OS=Homo sapiens OX=9606 GN=HNRNPCL4 PE=3 SV=1 4.37 2951.5 - 2.87E+07 - - - -2.7142 - 2.284 0.384 - 516 1 2 0 -0.0027 9 0 0 0 9.88E+08 7.23E+08 - - - 4.2658 1 221125_WJC_METTL3_EV_vs_WT_F03.16627.16627.2 1.81E-10 14/24 K.FC[160.03]ADSDGFSQELR.N "sp|P52732|KIF11_HUMAN,tr|A0A7I2V3A9|A0A7I2V3A9_HUMAN" 2 1530.6409 4.33 31963 16627 2 1530.636161 766.3277 Kinesin-like protein KIF11 OS=Homo sapiens OX=9606 GN=KIF11 PE=1 SV=2 4.03 2951.6 - 6.87E+06 - - - -3.1007 - 2.93 0.558 - 672.7 1 2 0 -0.0047 13 0 0 0 9.28E+08 2.15E+08 - - - 5.9199 0.9996 221125_WJC_METTL3_EV_vs_WT_F03.16628.16628.2 0.00122 13/20 K.TADDPSLSLIK.Y "sp|P39656|OST48_HUMAN,tr|U3KQ84|U3KQ84_HUMAN,tr|A0A0C4DGS1|A0A0C4DGS1_HUMAN" 3 1158.6132 1.8 31964 16628 2 1158.611199 580.3139 Dolichyl-diphosphooligosaccharide--protein glycosyltransferase 48 kDa subunit OS=Homo sapiens OX=9606 GN=DDOST PE=1 SV=4 4.21 2951.7 - 4.40E+06 - - - -1.7435 - 2.265 0.384 - 426.2 1 2 0 -0.002 11 0 0 0 2.07E+08 1.15E+08 - - - 4.0883 0.9999 221125_WJC_METTL3_EV_vs_WT_F03.16630.16630.3 2.79E-05 18/52 K.FPSLLTHNENMVAK[136.11].V sp|P62906|RL10A_HUMAN 1 1607.8221 1.03 31966 16630 3 1607.819128 536.948 60S ribosomal protein L10a OS=Homo sapiens OX=9606 GN=RPL10A PE=1 SV=2 6.75 2951.9 - 1.98E+06 - - - -1.8565 - 2.621 0.427 - 325.7 1 2 0 -0.003 14 0 0 0 4.72E+07 4.59E+07 - - - 5.8605 0.999 221125_WJC_METTL3_EV_vs_WT_F03.16632.16632.2 0.000431 16/26 R.AGSGLVLSGSEIPK[136.11].E "sp|Q6W2J9|BCOR_HUMAN,tr|H7BZ37|H7BZ37_HUMAN,tr|H7C2V9|H7C2V9_HUMAN,tr|H7BYY2|H7BYY2_HUMAN,tr|H7C231|H7C231_HUMAN" 5 1321.7333 1.66 31968 16632 2 1321.728374 661.8739 BCL-6 corepressor OS=Homo sapiens OX=9606 GN=BCOR PE=1 SV=1 6.05 2952.2 - 1.42E+06 - - - -3.7125 - 2.667 0.43 - 762.2 1 2 0 -0.0049 14 0 0 0 1.05E+08 6.33E+07 - - - 4.6771 1 221125_WJC_METTL3_EV_vs_WT_F03.16633.16633.2 1.16E-08 20-Dec R.NPEAALSPTFR[166.11].S "sp|Q86U44|MTA70_HUMAN,tr|B4E349|B4E349_HUMAN,tr|F5H6D8|F5H6D8_HUMAN,tr|B4DTN4|B4DTN4_HUMAN" 4 1211.6174 0.24 31969 16633 2 1211.614302 606.816 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 6 2952.3 - 1.34E+06 - - - -2.5627 - 2.744 0.544 - 739.1 1 2 0 -0.0031 11 0 0 0 5.59E+06 2.30E+07 - - - 5.7887 0.9984 221125_WJC_METTL3_EV_vs_WT_F03.16637.16637.2 4.27E-07 16-Oct K.SDVEAIFSK.Y "sp|P0DMR1|HNRC4_HUMAN,sp|P07910|HNRPC_HUMAN,sp|O60812|HNRC1_HUMAN,sp|B2RXH8|HNRC2_HUMAN,sp|B7ZW38|HNRC3_HUMAN,tr|G3V251|G3V251_HUMAN,tr|B4DY08|B4DY08_HUMAN,tr|G3V575|G3V575_HUMAN,tr|B4DSU6|B4DSU6_HUMAN,tr|G3V3K6|G3V3K6_HUMAN,tr|B2R5W2|B2R5W2_HUMAN,tr|G3V4C1|G3V4C1_HUMAN,tr|A0A0G2JPF8|A0A0G2JPF8_HUMAN,tr|A0A0G2JNQ3|A0A0G2JNQ3_HUMAN,tr|G3V576|G3V576_HUMAN,tr|G3V5X6|G3V5X6_HUMAN,tr|G3V2H6|G3V2H6_HUMAN,tr|G3V4W0|G3V4W0_HUMAN,tr|G3V555|G3V555_HUMAN,tr|G3V4M8|G3V4M8_HUMAN,tr|G3V2Q1|G3V2Q1_HUMAN" 21 994.4971 1.37 31971 16637 2 994.493227 498.2558 Heterogeneous nuclear ribonucleoprotein C-like 4 OS=Homo sapiens OX=9606 GN=HNRNPCL4 PE=3 SV=1 4.37 2952.9 - 5.13E+07 - - - -3.9216 - 2.207 0.388 - 422.5 1 2 0 -0.0039 9 0 0 0 9.86E+08 7.20E+08 - - - 4.1958 1 221125_WJC_METTL3_EV_vs_WT_F03.16638.16638.2 8.98E-07 15/28 K.EGPVLATSSGAGVFK[136.11].M "sp|Q9H4A3|WNK1_HUMAN,tr|F5GWT4|F5GWT4_HUMAN,tr|A0A6Q8PFM0|A0A6Q8PFM0_HUMAN" 3 1426.7547 1.69 31972 16638 2 1426.75168 714.3846 Serine\threonine-protein kinase WNK1 OS=Homo sapiens OX=9606 GN=WNK1 PE=1 SV=2 6.1 2952.9 - 5.08E+06 - - - -2.1482 - 2.614 0.608 - 692.2 1 2 0 -0.0031 15 0 0 0 1.64E+08 9.66E+07 - - - 5.8931 0.9998 221125_WJC_METTL3_EV_vs_WT_F03.16639.16639.2 0.319 14/26 R.AGSGLVLSGSEIPK.E "sp|Q6W2J9|BCOR_HUMAN,tr|H7BZ37|H7BZ37_HUMAN,tr|H7C2V9|H7C2V9_HUMAN,tr|H7BYY2|H7BYY2_HUMAN,tr|H7C231|H7C231_HUMAN" 5 1313.7191 1.66 31973 16639 2 1313.717263 657.8668 BCL-6 corepressor OS=Homo sapiens OX=9606 GN=BCOR PE=1 SV=1 6.05 2953 - 5.76E+06 - - - -1.3839 - 2.825 0.423 - 556.9 1 2 0 -0.0018 14 0 0 0 1.05E+08 6.33E+07 - - - 4.7708 0.9997 221125_WJC_METTL3_EV_vs_WT_F03.16640.16640.2 0.000427 16/24 K.QVLALQSQLADTK[136.11].K sp|P35580|MYH10_HUMAN 1 1421.7969 0.92 31974 16640 2 1421.794402 711.9057 Myosin-10 OS=Homo sapiens OX=9606 GN=MYH10 PE=1 SV=3 5.84 2953.1 - 4.23E+06 - - - -1.7879 - 2.832 0.353 - 931.4 1 2 0 -0.0025 13 0 0 0 1.24E+08 1.35E+08 - - - 4.3192 1 221125_WJC_METTL3_EV_vs_WT_F03.16641.16641.2 0.000139 13/24 K.FC[160.03]ADSDGFSQELR[166.11].N "sp|P52732|KIF11_HUMAN,tr|A0A7I2V3A9|A0A7I2V3A9_HUMAN" 2 1540.6492 4.33 31975 16641 2 1540.64537 771.3319 Kinesin-like protein KIF11 OS=Homo sapiens OX=9606 GN=KIF11 PE=1 SV=2 4.03 2953.2 - 3.92E+06 - - - -2.471 - 2.76 0.572 - 528.9 1 2 0 -0.0038 13 0 0 0 9.28E+08 2.15E+08 - - - 5.8702 0.9982 221125_WJC_METTL3_EV_vs_WT_F03.16644.16644.2 0.000446 16-Oct K.TGISDVFAK[136.11].N "sp|P19338|NUCL_HUMAN,tr|A0A7I2V506|A0A7I2V506_HUMAN,tr|A0A7I2V699|A0A7I2V699_HUMAN,tr|A0A7I2V2U7|A0A7I2V2U7_HUMAN,tr|A0A7I2V3F3|A0A7I2V3F3_HUMAN,tr|A0A7I2V428|A0A7I2V428_HUMAN,tr|A0A7I2V349|A0A7I2V349_HUMAN,tr|H7BY16|H7BY16_HUMAN,tr|A0A7I2V5M5|A0A7I2V5M5_HUMAN,tr|A0A7I2V2S8|A0A7I2V2S8_HUMAN,tr|C9JLB1|C9JLB1_HUMAN" 11 944.5058 1.15 31978 16644 2 944.502675 473.2602 Nucleolin OS=Homo sapiens OX=9606 GN=NCL PE=1 SV=3 5.5 2953.5 - 2.24E+06 - - - -3.3584 - 1.847 0.365 - 269.9 1 2 0 -0.0032 9 0 0 0 2.09E+08 1.81E+08 - - - 3.511 0.9861 221125_WJC_METTL3_EV_vs_WT_F03.16645.16645.2 0.0541 15/26 R.IYVGNASVAQDIPK.L sp|P51452|DUS3_HUMAN 1 1473.7827 2.2 31979 16645 2 1473.771755 737.8986 Dual specificity protein phosphatase 3 OS=Homo sapiens OX=9606 GN=DUSP3 PE=1 SV=1 5.83 2953.7 - 1.94E+06 - - - -7.4563 - 2.546 0.434 - 597.8 1 2 0 -0.011 14 0 0 0 3.80E+07 1.73E+07 - - - 4.5882 0.9995 221125_WJC_METTL3_EV_vs_WT_F03.16646.16646.2 0.00628 18-Aug K.INFDDNAEFR[166.11].Q "sp|Q96I99|SUCB2_HUMAN,tr|E9PDQ8|E9PDQ8_HUMAN" 2 1249.5603 1.98 31980 16646 2 1249.558679 625.7874 "Succinate--CoA ligase [GDP-forming] subunit beta, mitochondrial OS=Homo sapiens OX=9606 GN=SUCLG2 PE=1 SV=2" 4.03 2953.8 - 1.02E+06 - - - -1.2861 - 2.002 0.321 - 266.8 1 2 0 -0.0016 10 0 0 0 3.79E+07 1.92E+07 - - - 3.349 0.9988 221125_WJC_METTL3_EV_vs_WT_F03.16652.16652.2 6.92E-05 13/26 R.QLLLESQSQLDAAK[136.11].S "sp|Q9P2E9|RRBP1_HUMAN,tr|A0A087WU26|A0A087WU26_HUMAN,tr|A0A087WVV2|A0A087WVV2_HUMAN,tr|F8W7S5|F8W7S5_HUMAN" 4 1550.8395 1.3 31984 16652 2 1550.834976 776.427 Ribosome-binding protein 1 OS=Homo sapiens OX=9606 GN=RRBP1 PE=1 SV=5 4.37 2954.4 - 3.60E+06 - - - -2.941 - 2.881 0.27 - 584.2 1 2 0 -0.0046 14 0 0 0 6.60E+07 5.06E+07 - - - 3.6891 1 221125_WJC_METTL3_EV_vs_WT_F03.16653.16653.2 4.26E-06 17/28 R.VTFEADENENITVVK.G "sp|Q9NX63|MIC19_HUMAN,tr|F8WAR4|F8WAR4_HUMAN,tr|C9JRZ6|C9JRZ6_HUMAN" 3 1706.8363 2.58 31985 16653 2 1706.835765 854.4254 MICOS complex subunit MIC19 OS=Homo sapiens OX=9606 GN=CHCHD3 PE=1 SV=1 4 2954.5 - 3.43E+06 - - - -0.3111 - 3.306 0.655 - 768.3 1 2 0 -0.0005 15 0 0 0 7.71E+07 2.99E+07 - - - 6.8184 1 221125_WJC_METTL3_EV_vs_WT_F03.16656.16656.2 7.78E-07 18-Nov K.INFDDNAEFR.Q "sp|Q96I99|SUCB2_HUMAN,tr|E9PDQ8|E9PDQ8_HUMAN" 2 1239.552 1.95 31988 16656 2 1239.551601 620.7833 "Succinate--CoA ligase [GDP-forming] subunit beta, mitochondrial OS=Homo sapiens OX=9606 GN=SUCLG2 PE=1 SV=2" 4.03 2954.8 - 2.69E+06 - - - -0.3348 - 2.443 0.604 - 403.7 1 2 0 -0.0004 10 0 0 0 3.79E+07 1.94E+07 - - - 5.9953 0.9995 221125_WJC_METTL3_EV_vs_WT_F03.16658.16658.2 0.00192 16-Oct K.YDGIILPGK[136.11].- "sp|P62913|RL11_HUMAN,tr|Q5VVC8|Q5VVC8_HUMAN" 2 982.5579 1.68 31990 16658 2 982.555531 492.2862 60S ribosomal protein L11 OS=Homo sapiens OX=9606 GN=RPL11 PE=1 SV=2 5.83 2955 - 2.13E+06 - - - -2.3938 - 1.971 0.458 - 305.8 1 2 0 -0.0024 9 0 0 0 1.03E+08 6.12E+07 - - - 4.3861 0.9841 221125_WJC_METTL3_EV_vs_WT_F03.16659.16659.2 4.81E-06 24-Nov K.VLYDAEISQIHQS.V sp|P35908|K22E_HUMAN 1 1501.7413 - 31991 16659 2 1501.73792 751.8779 "Keratin, type II cytoskeletal 2 epidermal OS=Homo sapiens OX=9606 GN=KRT2 PE=1 SV=2" 4.35 2955.1 - 1.94E+06 - - - -2.2327 - 2.304 0.532 - 296.6 1 1 0 -0.0034 13 0 0 0 - - - - - 5.1114 0.8701 221125_WJC_METTL3_EV_vs_WT_F03.16660.16660.2 2.23E-05 15/26 K.DISTTLNADEAVAR[166.11].G "sp|Q92598|HS105_HUMAN,sp|O95757|HS74L_HUMAN,tr|D6RJ96|D6RJ96_HUMAN,tr|E9PDE8|E9PDE8_HUMAN,tr|A0A0A0MSM0|A0A0A0MSM0_HUMAN" 5 1484.7346 0.1 31992 16660 2 1484.722991 743.3746 Heat shock protein 105 kDa OS=Homo sapiens OX=9606 GN=HSPH1 PE=1 SV=1 4.03 2955.2 - 1.42E+06 - - - -7.833 - 2.631 0.098 - 695.1 1 2 0 -0.0116 14 0 0 0 4.46E+07 4.31E+08 - - - 2.1887 1 221125_WJC_METTL3_EV_vs_WT_F03.16664.16664.2 2.45E-07 16/20 K.IAIWTTEC[160.03]ENR[166.11].E "sp|P06730|IF4E_HUMAN,tr|D6RBW1|D6RBW1_HUMAN" 2 1401.6586 1.63 31995 16664 2 1401.655781 701.8366 Eukaryotic translation initiation factor 4E OS=Homo sapiens OX=9606 GN=EIF4E PE=1 SV=2 4.53 2955.6 - 5.19E+06 - - - -2.0255 - 2.715 0.552 - 1103.3 1 2 0 -0.0028 11 0 0 0 2.22E+08 1.36E+08 - - - 5.8191 0.9997 221125_WJC_METTL3_EV_vs_WT_F03.16666.16666.2 0.0161 13/26 R.LVVPATQC[160.03]GSLIGK[136.11].G sp|Q15365|PCBP1_HUMAN 1 1449.8105 0.74 31997 16666 2 1449.807457 725.9125 Poly(rC)-binding protein 1 OS=Homo sapiens OX=9606 GN=PCBP1 PE=1 SV=2 8.22 2955.7 - 3.84E+06 - - - -2.0892 - 2.26 0.533 - 359.5 1 2 0 -0.003 14 0 0 0 1.01E+08 1.38E+08 - - - 5.0229 0.9974 221125_WJC_METTL3_EV_vs_WT_F03.16667.16667.2 1.43 18-Sep R.LAYQELQIDR[166.11].K "sp|Q8N6H7|ARFG2_HUMAN,tr|E9PIY6|E9PIY6_HUMAN,tr|E9PQP3|E9PQP3_HUMAN,tr|H0YDN9|H0YDN9_HUMAN,tr|G5E9L0|G5E9L0_HUMAN,tr|A0A0D9SF70|A0A0D9SF70_HUMAN" 6 1257.6593 0.06 31998 16667 2 1257.660207 629.8369 ADP-ribosylation factor GTPase-activating protein 2 OS=Homo sapiens OX=9606 GN=ARFGAP2 PE=1 SV=1 4.37 2955.8 - 3.43E+06 - - - 0.7442 - 1.641 0.174 - 258.5 1 2 0 0.0009 10 0 0 0 7.46E+07 1.24E+09 - - - 1.7084 1 221125_WJC_METTL3_EV_vs_WT_F03.16673.16673.2 5.03E-08 14/26 R.LVVPATQC[160.03]GSLIGK.G sp|Q15365|PCBP1_HUMAN 1 1441.7963 0.74 32002 16673 2 1441.791119 721.9054 Poly(rC)-binding protein 1 OS=Homo sapiens OX=9606 GN=PCBP1 PE=1 SV=2 8.22 2956.5 - 4.00E+06 - - - -3.5837 - 2.473 0.608 - 471.5 1 2 0 -0.0052 14 0 0 0 1.01E+08 1.38E+08 - - - 5.8022 1 221125_WJC_METTL3_EV_vs_WT_F03.16674.16674.3 8.74E-06 13/44 R.TVIIEQSWGSPK.V "sp|P10809|CH60_HUMAN,tr|C9JL25|C9JL25_HUMAN,tr|A0A7I2V2X6|A0A7I2V2X6_HUMAN,tr|A0A7I2YQK6|A0A7I2YQK6_HUMAN,tr|A0A7I2V599|A0A7I2V599_HUMAN,tr|E7EXB4|E7EXB4_HUMAN,tr|C9JL19|C9JL19_HUMAN,tr|A0A7I2YQ71|A0A7I2YQ71_HUMAN,tr|E7ESH4|E7ESH4_HUMAN,tr|A0A7I2V5M1|A0A7I2V5M1_HUMAN,tr|A0A7I2V5K3|A0A7I2V5K3_HUMAN,tr|A0A7I2V369|A0A7I2V369_HUMAN,tr|C9JCQ4|C9JCQ4_HUMAN" 13 1343.7085 1.08 32003 16674 3 1343.705389 448.9101 "60 kDa heat shock protein, mitochondrial OS=Homo sapiens OX=9606 GN=HSPD1 PE=1 SV=2" 5.66 2956.6 - 5.32E+06 - - - -2.3271 - 2.381 0.544 - 257.9 1 2 0 -0.0031 12 0 0 0 1.07E+08 9.89E+07 - - - 7.0088 0.9996 221125_WJC_METTL3_EV_vs_WT_F03.16675.16675.2 0.00293 13/18 R.LAYQELQIDR.K "sp|Q8N6H7|ARFG2_HUMAN,tr|E9PIY6|E9PIY6_HUMAN,tr|E9PQP3|E9PQP3_HUMAN,tr|H0YDN9|H0YDN9_HUMAN,tr|G5E9L0|G5E9L0_HUMAN,tr|A0A0D9SF70|A0A0D9SF70_HUMAN" 6 1247.651 0.08 32004 16675 2 1247.648917 624.8328 ADP-ribosylation factor GTPase-activating protein 2 OS=Homo sapiens OX=9606 GN=ARFGAP2 PE=1 SV=1 4.37 2956.7 - 3.50E+06 - - - -1.6703 - 2.335 0.359 - 621.1 1 2 0 -0.0021 10 0 0 0 6.90E+07 9.09E+08 - - - 4.059 0.999 221125_WJC_METTL3_EV_vs_WT_F03.16679.16679.2 0.000354 13/24 K.QVLALQSQLADTK.K sp|P35580|MYH10_HUMAN 1 1413.7827 0.92 32006 16679 2 1413.783431 707.8986 Myosin-10 OS=Homo sapiens OX=9606 GN=MYH10 PE=1 SV=3 5.84 2957.2 - 8.22E+06 - - - 0.4859 - 1.733 0.27 - 206.8 1 2 0 0.0007 13 0 0 0 1.24E+08 1.35E+08 - - - 2.4462 0.9995 221125_WJC_METTL3_EV_vs_WT_F03.16680.16680.3 0.171 13/40 R.GFAFVEYESHR[166.11].A "sp|A0AV96|RBM47_HUMAN,sp|Q9NQ94|A1CF_HUMAN,sp|Q8TBY0|RBM46_HUMAN,tr|Q5T0W7|Q5T0W7_HUMAN,tr|D6RBS9|D6RBS9_HUMAN,tr|B7Z8Z7|B7Z8Z7_HUMAN,tr|F8W9F8|F8W9F8_HUMAN,tr|D6R9D6|D6R9D6_HUMAN" 8 1350.6232 1.11 32007 16680 3 1350.619775 451.215 RNA-binding protein 47 OS=Homo sapiens OX=9606 GN=RBM47 PE=1 SV=2 5.4 2957.3 - 3.50E+06 - - - -2.5507 - 2.048 0.367 - 161.1 1 2 0 -0.0034 11 0 0 0 5.42E+07 4.89E+07 - - - 4.6672 1 221125_WJC_METTL3_EV_vs_WT_F03.16682.16682.2 1.76E-09 17/24 K.ITSYFLNEGSQAR[166.11].P sp|O75792|RNH2A_HUMAN 1 1494.7342 7.26 32009 16682 2 1494.732788 748.3744 Ribonuclease H2 subunit A OS=Homo sapiens OX=9606 GN=RNASEH2A PE=1 SV=2 6 2957.4 - 3.13E+06 - - - -0.9627 - 2.861 0.602 - 1316 1 1 0 -0.0014 13 0 0 0 4.35E+08 6.00E+07 - - - 6.1848 1 221125_WJC_METTL3_EV_vs_WT_F03.16683.16683.2 1.18E-09 15/28 R.VTFEADENENITVVK[136.11].G "sp|Q9NX63|MIC19_HUMAN,tr|F8WAR4|F8WAR4_HUMAN,tr|C9JRZ6|C9JRZ6_HUMAN" 3 1714.8505 2.58 32010 16683 2 1714.845409 858.4325 MICOS complex subunit MIC19 OS=Homo sapiens OX=9606 GN=CHCHD3 PE=1 SV=1 4 2957.5 - 1.53E+06 - - - -2.9664 - 3.256 0.623 - 615.4 1 2 0 -0.0051 15 0 0 0 7.71E+07 2.99E+07 - - - 6.5432 0.9995 221125_WJC_METTL3_EV_vs_WT_F03.16685.16685.2 1.97E-05 13/24 R.EVDDLGPEVGDIK.L sp|O43143|DHX15_HUMAN 1 1384.6722 1.42 32011 16685 2 1384.669284 693.3434 Pre-mRNA-splicing factor ATP-dependent RNA helicase DHX15 OS=Homo sapiens OX=9606 GN=DHX15 PE=1 SV=2 3.77 2957.8 - 1.58E+06 - - - -2.0987 - 1.988 0.437 - 449.9 1 2 0 -0.0029 13 0 0 0 1.76E+08 1.23E+08 - - - 4.0313 0.9999 221125_WJC_METTL3_EV_vs_WT_F03.16690.16690.3 0.000124 Dec-40 R.GFAFVEYESHR.A "sp|A0AV96|RBM47_HUMAN,sp|Q9NQ94|A1CF_HUMAN,sp|Q8TBY0|RBM46_HUMAN,tr|Q5T0W7|Q5T0W7_HUMAN,tr|D6RBS9|D6RBS9_HUMAN,tr|B7Z8Z7|B7Z8Z7_HUMAN,tr|F8W9F8|F8W9F8_HUMAN,tr|D6R9D6|D6R9D6_HUMAN" 8 1340.6149 1.07 32015 16690 3 1340.611489 447.8789 RNA-binding protein 47 OS=Homo sapiens OX=9606 GN=RBM47 PE=1 SV=2 5.4 2958.1 - 4.67E+06 - - - -2.5817 - 1.912 0.497 - 121.9 1 2 0 -0.0035 11 0 0 0 5.42E+07 5.07E+07 - - - 5.9214 0.9999 221125_WJC_METTL3_EV_vs_WT_F03.16691.16691.2 4.23E-09 14/20 R.VC[160.03]EEIAIIPSK[136.11].K "sp|P08708|RS17_HUMAN,tr|H0YN73|H0YN73_HUMAN,tr|H3BNC9|H3BNC9_HUMAN,tr|H0YN88|H0YN88_HUMAN,tr|A0A075B716|A0A075B716_HUMAN" 5 1265.6781 1.5 32016 16691 2 1265.679518 633.8463 40S ribosomal protein S17 OS=Homo sapiens OX=9606 GN=RPS17 PE=1 SV=2 4.53 2958.2 - 2.68E+06 - - - 1.1401 - 2.653 0.49 - 595.1 1 2 0 0.0014 11 0 0 0 1.24E+09 8.25E+08 - - - 5.2992 0.9954 221125_WJC_METTL3_EV_vs_WT_F03.16692.16692.3 0.0033 Nov-52 K.DISTTLNADEAVAR[166.11].G "sp|Q92598|HS105_HUMAN,sp|O95757|HS74L_HUMAN,tr|D6RJ96|D6RJ96_HUMAN,tr|E9PDE8|E9PDE8_HUMAN,tr|A0A0A0MSM0|A0A0A0MSM0_HUMAN" 5 1484.7346 0.06 32017 16692 3 1484.725794 495.9188 Heat shock protein 105 kDa OS=Homo sapiens OX=9606 GN=HSPH1 PE=1 SV=1 4.03 2958.3 - 2.65E+06 - - - -5.9452 - 2.377 0.358 - 142 1 2 0 -0.0088 14 0 0 0 2.74E+06 4.59E+07 - - - 4.8299 1 221125_WJC_METTL3_EV_vs_WT_F03.16693.16693.3 6.25E-09 Dec-48 K.FC[160.03]ADSDGFSQELR.N "sp|P52732|KIF11_HUMAN,tr|A0A7I2V3A9|A0A7I2V3A9_HUMAN" 2 1530.6409 3.32 32018 16693 3 1530.639051 511.2209 Kinesin-like protein KIF11 OS=Homo sapiens OX=9606 GN=KIF11 PE=1 SV=2 4.03 2958.4 - 2.50E+06 - - - -1.2126 - 2.264 0.694 - 126.9 1 2 0 -0.0019 13 0 0 0 3.01E+07 9.07E+06 - - - 8.4924 0.9994 221125_WJC_METTL3_EV_vs_WT_F03.16694.16694.2 0.000383 13/24 K.TISTSDPAEVLVK[136.11].N "sp|Q86UE4|LYRIC_HUMAN,tr|E5RJU9|E5RJU9_HUMAN" 2 1366.7435 6.24 32019 16694 2 1366.740845 684.379 Protein LYRIC OS=Homo sapiens OX=9606 GN=MTDH PE=1 SV=2 4.37 2958.5 - 2.01E+06 - - - -1.9506 - 2.017 0.384 - 272.6 1 2 0 -0.0027 13 0 0 0 3.84E+08 6.15E+07 - - - 3.6771 0.9871 221125_WJC_METTL3_EV_vs_WT_F03.16695.16695.2 1.52E-05 13/26 A.SAVPELATDPELEK[136.11].K "sp|Q86U44|MTA70_HUMAN,tr|B4E349|B4E349_HUMAN,tr|F5H6D8|F5H6D8_HUMAN,tr|H0YFV6|H0YFV6_HUMAN,tr|B4DTN4|B4DTN4_HUMAN" 5 1505.7705 0.01 32020 16695 2 1505.772936 753.8925 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 4 2958.6 - 1.36E+06 - - - 1.6483 - 2.2 0.528 - 482.6 1 1 0 0.0025 14 0 0 0 7.03E+06 7.04E+08 - - - 4.9186 0.9992 221125_WJC_METTL3_EV_vs_WT_F03.16699.16699.2 0.017 20-Dec K.TLQALQIPAAK.L "sp|P46940|IQGA1_HUMAN,tr|A0A0J9YXZ5|A0A0J9YXZ5_HUMAN" 2 1152.6867 0.9 32022 16699 2 1152.684853 577.3506 Ras GTPase-activating-like protein IQGAP1 OS=Homo sapiens OX=9606 GN=IQGAP1 PE=1 SV=1 8.41 2959.1 - 4.63E+06 - - - -1.5668 - 1.869 0.318 - 291.7 1 2 0 -0.0018 11 0 0 0 5.97E+07 6.60E+07 - - - 3.081 1 221125_WJC_METTL3_EV_vs_WT_F03.16700.16700.2 3.93E-09 18-Nov R.QSC[160.03]YLC[160.03]DLPR[166.11].M "sp|Q7Z5L9|I2BP2_HUMAN,sp|Q9H1B7|I2BPL_HUMAN" 2 1320.583 1.33 32023 16700 2 1320.580207 661.2988 Interferon regulatory factor 2-binding protein 2 OS=Homo sapiens OX=9606 GN=IRF2BP2 PE=1 SV=2 5.82 2959.1 - 2.40E+06 - - - -2.1241 - 2.366 0.63 - 704.3 1 2 0 -0.0028 10 0 0 0 7.58E+07 5.72E+07 - - - 6.0972 0.9994 221125_WJC_METTL3_EV_vs_WT_F03.16701.16701.2 0.000245 18-Oct K.EDALNLSVPR.Q sp|Q9P2D1|CHD7_HUMAN 1 1112.5826 1.31 32024 16701 2 1112.579595 557.2986 Chromodomain-helicase-DNA-binding protein 7 OS=Homo sapiens OX=9606 GN=CHD7 PE=1 SV=3 4.37 2959.3 - 2.26E+06 - - - -2.6901 - 2.112 0.448 - 355.6 1 2 0 -0.003 10 0 0 0 4.83E+07 3.70E+07 - - - 4.4359 0.9994 221125_WJC_METTL3_EV_vs_WT_F03.16702.16702.2 1.87E-08 15/26 K.DISTTLNADEAVAR.G "sp|Q92598|HS105_HUMAN,sp|O95757|HS74L_HUMAN,tr|D6RJ96|D6RJ96_HUMAN,tr|E9PDE8|E9PDE8_HUMAN,tr|A0A0A0MSM0|A0A0A0MSM0_HUMAN" 5 1474.7264 0.1 32025 16702 2 1474.721098 738.3705 Heat shock protein 105 kDa OS=Homo sapiens OX=9606 GN=HSPH1 PE=1 SV=1 4.03 2959.4 - 1.93E+06 - - - -3.562 - 2.65 0.566 - 600.6 1 2 0 -0.0053 14 0 0 0 4.46E+07 4.29E+08 - - - 5.6654 0.9993 221125_WJC_METTL3_EV_vs_WT_F03.16704.16704.2 2.91E-05 22-Dec R.IFTSIGEDYDER[166.11].V "sp|P35232|PHB_HUMAN,tr|C9JZ20|C9JZ20_HUMAN,tr|E7ESE2|E7ESE2_HUMAN,tr|E9PCW0|E9PCW0_HUMAN,tr|C9JW96|C9JW96_HUMAN" 5 1453.6601 1.53 32027 16704 2 1453.655086 727.8373 Prohibitin OS=Homo sapiens OX=9606 GN=PHB PE=1 SV=1 3.92 2959.6 - 2.55E+06 - - - -3.421 - 2.307 0.486 - 512.7 1 2 0 -0.005 12 0 0 0 2.51E+08 1.64E+08 - - - 4.8286 0.9992 221125_WJC_METTL3_EV_vs_WT_F03.16705.16705.3 0.00213 Dec-40 K.QMVIDVLHPGK.A "sp|P62847|RS24_HUMAN,tr|A0A2R8YD14|A0A2R8YD14_HUMAN,tr|A0A2R8Y849|A0A2R8Y849_HUMAN,tr|E7ETK0|E7ETK0_HUMAN" 4 1235.6696 0.89 32028 16705 3 1235.668079 412.8972 40S ribosomal protein S24 OS=Homo sapiens OX=9606 GN=RPS24 PE=1 SV=1 6.74 2959.8 - 1.21E+06 - - - -1.2536 - 1.7 0.315 - 155.9 1 2 0 -0.0015 11 0 0 0 7.44E+07 8.31E+07 - - - 3.5589 1 221125_WJC_METTL3_EV_vs_WT_F03.16713.16713.3 0.000972 15/44 R.ILFRPVASQLPR.L "sp|P35232|PHB_HUMAN,tr|C9JZ20|C9JZ20_HUMAN,tr|E7ESE2|E7ESE2_HUMAN,tr|E9PCW0|E9PCW0_HUMAN,tr|C9JW96|C9JW96_HUMAN" 5 1395.8351 1.18 32034 16713 3 1395.83441 466.2856 Prohibitin OS=Homo sapiens OX=9606 GN=PHB PE=1 SV=1 12 2960.5 - 4.14E+06 - - - -0.4614 - 2.806 0.415 - 287.3 1 2 0 -0.0006 12 0 0 0 1.04E+08 8.77E+07 - - - 6.0265 0.9998 221125_WJC_METTL3_EV_vs_WT_F03.16714.16714.2 0.00678 18-Oct R.QSC[160.03]YLC[160.03]DLPR.M "sp|Q7Z5L9|I2BP2_HUMAN,sp|Q9H1B7|I2BPL_HUMAN" 2 1310.5747 1.33 32035 16714 2 1310.572593 656.2946 Interferon regulatory factor 2-binding protein 2 OS=Homo sapiens OX=9606 GN=IRF2BP2 PE=1 SV=2 5.82 2960.6 - 3.99E+06 - - - -1.6397 - 2.128 0.484 - 539.8 1 2 0 -0.0021 10 0 0 0 7.58E+07 5.72E+07 - - - 4.7231 0.9695 221125_WJC_METTL3_EV_vs_WT_F03.16716.16716.2 0.00228 24-Oct R.ASLEDAPVDDLTR[166.11].K "sp|Q7Z2W4|ZCCHV_HUMAN,tr|C9J6P4|C9J6P4_HUMAN,tr|A0A7P0T8C6|A0A7P0T8C6_HUMAN" 3 1410.6866 1.33 32037 16716 2 1410.678484 706.3506 Zinc finger CCCH-type antiviral protein 1 OS=Homo sapiens OX=9606 GN=ZC3HAV1 PE=1 SV=3 3.84 2960.7 - 7.94E+06 - - - -5.7589 - 1.36 0.35 - 168.7 1 2 0 -0.0081 13 0 0 0 7.35E+07 5.55E+07 - - - 2.4127 0.9991 221125_WJC_METTL3_EV_vs_WT_F03.16717.16717.2 0.076 20-Dec K.TLQALQIPAAK[136.11].L "sp|P46940|IQGA1_HUMAN,tr|A0A0J9YXZ5|A0A0J9YXZ5_HUMAN" 2 1160.7009 0.9 32038 16717 2 1160.700252 581.3577 Ras GTPase-activating-like protein IQGAP1 OS=Homo sapiens OX=9606 GN=IQGAP1 PE=1 SV=1 8.41 2960.7 - 3.80E+06 - - - -0.523 - 1.678 0.277 - 428 1 2 0 -0.0006 11 0 0 0 5.97E+07 6.60E+07 - - - 2.487 1 221125_WJC_METTL3_EV_vs_WT_F03.16719.16719.3 2.10E-07 21/48 R.IETLDPALIR[166.11]PGR[166.11].L sp|P62191|PRS4_HUMAN 1 1469.8469 0.61 32040 16719 3 1469.847684 490.9562 26S proteasome regulatory subunit 4 OS=Homo sapiens OX=9606 GN=PSMC1 PE=1 SV=1 6.07 2961 - 2.20E+06 - - - 0.5313 - 3.048 0.487 - 392.1 1 2 0 0.0008 13 0 0 0 4.96E+07 8.08E+07 - - - 6.991 0.9998 221125_WJC_METTL3_EV_vs_WT_F03.16720.16720.3 7.24E-06 15/40 K.QMVIDVLHPGK[136.11].A "sp|P62847|RS24_HUMAN,tr|A0A2R8YD14|A0A2R8YD14_HUMAN,tr|A0A2R8Y849|A0A2R8Y849_HUMAN,tr|E7ETK0|E7ETK0_HUMAN" 4 1243.6838 0.9 32041 16720 3 1243.681137 415.5686 40S ribosomal protein S24 OS=Homo sapiens OX=9606 GN=RPS24 PE=1 SV=1 6.74 2961.1 - 1.62E+06 - - - -2.1637 - 2.18 0.381 - 271.3 1 2 0 -0.0027 11 0 0 0 7.49E+07 8.31E+07 - - - 5.001 0.9995 221125_WJC_METTL3_EV_vs_WT_F03.16721.16721.3 0.0287 Sep-32 K.VWKPQLFER.E "sp|Q13084|RM28_HUMAN,tr|A2IDC6|A2IDC6_HUMAN,tr|A2IDC7|A2IDC7_HUMAN,tr|Q4TT37|Q4TT37_HUMAN" 4 1201.6608 1.24 32042 16721 3 1201.657999 401.5609 "39S ribosomal protein L28, mitochondrial OS=Homo sapiens OX=9606 GN=MRPL28 PE=1 SV=4" 8.72 2961.2 - 1.47E+06 - - - -2.3126 - 1.952 0.35 - 149.3 1 2 0 -0.0028 9 0 0 0 1.39E+07 1.12E+07 - - - 4.4572 1 221125_WJC_METTL3_EV_vs_WT_F03.16727.16727.2 2.12E-08 22-Dec R.IFTSIGEDYDER.V "sp|P35232|PHB_HUMAN,tr|C9JZ20|C9JZ20_HUMAN,tr|E7ESE2|E7ESE2_HUMAN,tr|E9PCW0|E9PCW0_HUMAN,tr|C9JW96|C9JW96_HUMAN" 5 1443.6518 1.6 32046 16727 2 1443.650209 722.8332 Prohibitin OS=Homo sapiens OX=9606 GN=PHB PE=1 SV=1 3.92 2961.8 - 8.18E+06 - - - -1.0944 - 2.457 0.632 - 607.8 1 2 0 -0.0016 12 0 0 0 2.64E+08 1.64E+08 - - - 6.0737 1 221125_WJC_METTL3_EV_vs_WT_F03.16729.16729.2 3.96E-09 24-Nov R.FSGSGSGTDFTLK.L "sp|A2NJV5|KV229_HUMAN,sp|A0A087WW87|KV240_HUMAN,sp|P06310|KV230_HUMAN,sp|A0A075B6S2|KVD29_HUMAN,sp|P01614|KVD40_HUMAN,sp|P01615|KVD28_HUMAN,sp|A0A075B6S6|KVD30_HUMAN,sp|A0A075B6P5|KV228_HUMAN,sp|A0A0A0MRZ7|KVD26_HUMAN" 9 1302.6092 26.55 32048 16729 2 1302.606976 652.3119 Immunoglobulin kappa variable 2-29 OS=Homo sapiens OX=9606 GN=IGKV2-29 PE=3 SV=2 5.84 2961.9 - 3.26E+06 - - - -1.7043 - 2.295 0.655 - 212.7 1 2 0 -0.0022 13 0 0 0 1.56E+08 5.87E+06 - - - 6.0102 0.9977 221125_WJC_METTL3_EV_vs_WT_F03.16732.16732.2 0.000307 16-Sep R.VLDELTLTK.A "sp|P13645|K1C10_HUMAN,tr|A0A1B0GVI3|A0A1B0GVI3_HUMAN" 2 1030.591 999 32051 16732 2 1030.586509 516.3028 "Keratin, type I cytoskeletal 10 OS=Homo sapiens OX=9606 GN=KRT10 PE=1 SV=6" 4.37 2962.3 - 1.58E+06 - - - -4.3839 - 2.013 0.422 - 238.1 1 2 0 -0.0045 9 0 0 0 1.61E+08 0.00E+00 - - - 4.1805 0.9969 221125_WJC_METTL3_EV_vs_WT_F03.16733.16733.3 0.0809 Oct-48 R.IETLDPALIRPGR.L sp|P62191|PRS4_HUMAN 1 1449.8304 0.61 32052 16733 3 1449.831172 484.2841 26S proteasome regulatory subunit 4 OS=Homo sapiens OX=9606 GN=PSMC1 PE=1 SV=1 6.07 2962.3 - 1.26E+06 - - - 0.558 - 1.785 0.218 - 83.3 1 2 0 0.0008 13 0 0 0 4.93E+07 8.08E+07 - - - 2.5412 1 221125_WJC_METTL3_EV_vs_WT_F03.16734.16734.3 3.80E-06 19/52 K.DYGVYLEDSGHTLR[166.11].G "sp|Q13162|PRDX4_HUMAN,tr|H7C3T4|H7C3T4_HUMAN" 2 1633.7612 0.52 32053 16734 3 1633.760591 545.5943 Peroxiredoxin-4 OS=Homo sapiens OX=9606 GN=PRDX4 PE=1 SV=1 4.54 2962.4 - 1.22E+06 - - - -0.3544 - 2.593 0.543 - 339.8 1 2 0 -0.0006 14 0 0 0 6.20E+06 1.19E+07 - - - 7.1259 0.9998 221125_WJC_METTL3_EV_vs_WT_F03.16735.16735.2 0.000534 30-Nov K.TLPPATSTEPSVILSK[136.11].S "sp|Q86UE4|LYRIC_HUMAN,tr|H0YBJ8|H0YBJ8_HUMAN,tr|E5RJU9|E5RJU9_HUMAN" 3 1647.9175 1.09 32054 16735 2 1647.914788 824.966 Protein LYRIC OS=Homo sapiens OX=9606 GN=MTDH PE=1 SV=2 5.66 2962.6 - 1.01E+06 - - - -1.6172 - 2.227 0.475 - 195.3 1 2 0 -0.0027 16 0 0 0 1.70E+07 1.57E+07 - - - 4.517 0.9988 221125_WJC_METTL3_EV_vs_WT_F03.16736.16736.2 0.0379 16-Oct R.YQGVNLYIK.N "sp|Q13310|PABP4_HUMAN,tr|A0A7I2V5W9|A0A7I2V5W9_HUMAN,tr|H0YEU6|H0YEU6_HUMAN,tr|B1ANR0|B1ANR0_HUMAN,tr|A0A7I2V4L7|A0A7I2V4L7_HUMAN,tr|A0A7I2V598|A0A7I2V598_HUMAN,tr|H0Y5F5|H0Y5F5_HUMAN" 7 1096.5917 1.15 32055 16736 2 1096.589836 549.3031 Polyadenylate-binding protein 4 OS=Homo sapiens OX=9606 GN=PABPC4 PE=1 SV=1 8.5 2962.7 - 549362 - - - -1.6962 - 1.602 0.315 - 197.9 1 2 0 -0.0019 9 0 0 0 2.15E+07 1.86E+07 - - - 2.7304 1 221125_WJC_METTL3_EV_vs_WT_F03.16739.16739.2 0.000441 17/26 H.ISDTSVVLSMDNNR.N "sp|P48668|K2C6C_HUMAN,sp|P12035|K2C3_HUMAN,sp|P04259|K2C6B_HUMAN,sp|P02538|K2C6A_HUMAN" 4 1549.7406 1085.73 32056 16739 2 1549.736783 775.8776 "Keratin, type II cytoskeletal 6C OS=Homo sapiens OX=9606 GN=KRT6C PE=1 SV=3" 4.21 2963.1 - 2.28E+06 - - - -2.4765 - 3.478 0.535 - 1063.9 1 1 0 -0.0038 14 0 0 0 2.40E+08 2.21E+05 - - - 6.1192 1 221125_WJC_METTL3_EV_vs_WT_F03.16741.16741.3 1.34E-07 18/64 R.VVLSVSSGGQHTVLLVK[136.11].D sp|P18754|RCC1_HUMAN 1 1730.0182 0.63 32058 16741 3 1730.017559 577.68 Regulator of chromosome condensation OS=Homo sapiens OX=9606 GN=RCC1 PE=1 SV=1 8.73 2963.3 - 3.05E+06 - - - -0.3532 - 2.997 0.568 - 305.7 1 2 0 -0.0006 17 0 0 0 1.80E+07 2.86E+07 - - - 7.6454 1 221125_WJC_METTL3_EV_vs_WT_F03.16742.16742.2 4.24E-08 15/24 R.VYNASSTIVPSLK.H "sp|Q9NRG9|AAAS_HUMAN,tr|H3BU82|H3BU82_HUMAN,tr|F8VZ44|F8VZ44_HUMAN" 3 1377.7504 1.56 32059 16742 2 1377.75454 689.8825 Aladin OS=Homo sapiens OX=9606 GN=AAAS PE=1 SV=1 8.56 2963.4 - 1.30E+06 - - - 3.0187 - 2.771 0.593 - 695.1 1 2 0 0.0042 13 0 0 0 2.65E+07 1.70E+07 - - - 6.0354 1 221125_WJC_METTL3_EV_vs_WT_F03.16743.16743.2 2.76E-09 15/26 R.QFVTPADVVSGNPK[136.11].L "sp|P13797|PLST_HUMAN,sp|Q14651|PLSI_HUMAN,tr|A0A0A0MSQ0|A0A0A0MSQ0_HUMAN,tr|H7C4N2|H7C4N2_HUMAN" 4 1465.7656 1.02 32060 16743 2 1465.766965 733.8901 Plastin-3 OS=Homo sapiens OX=9606 GN=PLS3 PE=1 SV=4 5.84 2963.5 - 1.28E+06 - - - 0.9012 - 2.629 0.588 - 817.2 1 2 0 0.0013 14 0 0 0 5.05E+07 4.95E+07 - - - 5.8092 0.995 221125_WJC_METTL3_EV_vs_WT_F03.16744.16744.3 0.000205 Dec-40 G.IHLLDPDVVAR[166.11].F sp|Q86U44|MTA70_HUMAN 1 1256.7116 0.05 32061 16744 3 1256.71041 419.9112 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 5.21 2963.6 - 1.20E+06 - - - -0.9795 - 2.407 0.441 - 358.4 1 1 0 -0.0012 11 0 0 0 2.03E+06 3.95E+07 - - - 5.9517 0.9992 221125_WJC_METTL3_EV_vs_WT_F03.16745.16745.2 0.0214 16-Aug R.DMPYQPFSK.G "sp|O15371|EIF3D_HUMAN,tr|B0QYA8|B0QYA8_HUMAN,tr|B0QYA6|B0QYA6_HUMAN,tr|B0QYA5|B0QYA5_HUMAN" 4 1111.5008 0.81 32062 16745 2 1111.501114 556.7577 Eukaryotic translation initiation factor 3 subunit D OS=Homo sapiens OX=9606 GN=EIF3D PE=1 SV=1 5.83 2963.7 - 3.34E+06 - - - 0.2537 - 1.24 0.404 - 209.6 1 2 0 0.0003 9 0 0 0 7.89E+07 9.78E+07 - - - 2.6472 0.999 221125_WJC_METTL3_EV_vs_WT_F03.16748.16748.3 0.00472 Nov-48 R.ILHGLGFTPAMQR.K "sp|Q9UG63|ABCF2_HUMAN,tr|C9JZV3|C9JZV3_HUMAN,tr|C9JHK9|C9JHK9_HUMAN" 3 1439.7707 0.57 32065 16748 3 1439.774399 480.9309 ATP-binding cassette sub-family F member 2 OS=Homo sapiens OX=9606 GN=ABCF2 PE=1 SV=2 9.76 2964 - 937951 - - - 2.5421 - 1.991 0.331 - 185.8 1 2 0 0.0037 13 0 0 0 1.21E+07 2.15E+07 - - - 4.0964 0.9997 221125_WJC_METTL3_EV_vs_WT_F03.16749.16749.2 0.00019 16-Oct R.YQGVNLYIK[136.11].N "sp|Q13310|PABP4_HUMAN,tr|A0A7I2V5W9|A0A7I2V5W9_HUMAN,tr|H0YEU6|H0YEU6_HUMAN,tr|B1ANR0|B1ANR0_HUMAN,tr|A0A7I2V4L7|A0A7I2V4L7_HUMAN,tr|A0A7I2V598|A0A7I2V598_HUMAN,tr|H0Y5F5|H0Y5F5_HUMAN" 7 1104.6059 1.65 32066 16749 2 1104.604751 553.3102 Polyadenylate-binding protein 4 OS=Homo sapiens OX=9606 GN=PABPC4 PE=1 SV=1 8.5 2964.2 - 824997 - - - -1.0366 - 1.595 0.453 - 175 1 2 0 -0.0011 9 0 0 0 2.10E+07 1.27E+07 - - - 3.7372 0.9918 221125_WJC_METTL3_EV_vs_WT_F03.16750.16750.2 2.57E-05 13/28 K.VYEDSGIPLPAESPK.K "sp|Q8IXM2|BAP18_HUMAN,tr|H0YIS7|H0YIS7_HUMAN,tr|F8W038|F8W038_HUMAN,tr|F8W1H0|F8W1H0_HUMAN" 4 1600.7985 2.45 32067 16750 2 1600.805276 801.4065 Chromatin complexes subunit BAP18 OS=Homo sapiens OX=9606 GN=BAP18 PE=1 SV=1 4.14 2964.3 - 767214 - - - 4.2616 - 2.23 0.225 - 376.4 1 2 0 0.0068 15 0 0 0 3.15E+07 1.29E+07 - - - 2.6725 0.9995 221125_WJC_METTL3_EV_vs_WT_F03.16751.16751.2 0.00114 30-Nov K.TLPPATSTEPSVILSK.S "sp|Q86UE4|LYRIC_HUMAN,tr|H0YBJ8|H0YBJ8_HUMAN,tr|E5RJU9|E5RJU9_HUMAN" 3 1639.9033 1.11 32068 16751 2 1639.900907 820.9589 Protein LYRIC OS=Homo sapiens OX=9606 GN=MTDH PE=1 SV=2 5.66 2964.4 - 626827 - - - -1.4306 - 1.899 0.38 - 178.8 1 2 0 -0.0023 16 0 0 0 1.31E+07 1.18E+07 - - - 3.4237 1 221125_WJC_METTL3_EV_vs_WT_F03.16752.16752.3 1.95E-06 Dec-40 R.VC[160.03]EEIAIIPSK[136.11].K "sp|P08708|RS17_HUMAN,tr|H0YN73|H0YN73_HUMAN,tr|H3BNC9|H3BNC9_HUMAN,tr|H0YN88|H0YN88_HUMAN,tr|A0A075B716|A0A075B716_HUMAN" 5 1265.6781 1.36 32069 16752 3 1265.676893 422.9 40S ribosomal protein S17 OS=Homo sapiens OX=9606 GN=RPS17 PE=1 SV=2 4.53 2964.6 - 540998 - - - -0.9339 - 2.542 0.456 - 233.2 1 2 0 -0.0012 11 0 0 0 3.59E+07 2.63E+07 - - - 6.274 1 221125_WJC_METTL3_EV_vs_WT_F03.16753.16753.3 2.60E-05 14/52 R.VDLYQQASPPDALR.W sp|P48634|PRC2A_HUMAN 1 1571.7944 2.72 32070 16753 3 1571.794539 524.9387 Protein PRRC2A OS=Homo sapiens OX=9606 GN=PRRC2A PE=1 SV=3 4.21 2964.7 - 447376 - - - 0.1069 - 2.742 0.505 - 337.8 1 2 0 0.0002 14 0 0 0 1.08E+07 3.98E+06 - - - 6.8508 0.9992 221125_WJC_METTL3_EV_vs_WT_F03.16757.16757.3 0.0245 Nov-48 R.ILHGLGFTPAMQR[166.11].K "sp|Q9UG63|ABCF2_HUMAN,tr|C9JZV3|C9JZV3_HUMAN,tr|C9JHK9|C9JHK9_HUMAN" 3 1449.779 0.57 32072 16757 3 1449.7765 484.2669 ATP-binding cassette sub-family F member 2 OS=Homo sapiens OX=9606 GN=ABCF2 PE=1 SV=2 9.76 2965.1 - 2.46E+06 - - - -1.7306 - 1.618 0.356 - 95 1 2 0 -0.0025 13 0 0 0 1.21E+07 2.15E+07 - - - 3.813 0.9974 221125_WJC_METTL3_EV_vs_WT_F03.16758.16758.2 0.0907 16-Oct R.AGLQFPVGR[166.11].V "sp|P16104|H2AX_HUMAN,sp|Q9BTM1|H2AJ_HUMAN,sp|Q93077|H2A1C_HUMAN,sp|Q99878|H2A1J_HUMAN,sp|Q16777|H2A2C_HUMAN,sp|Q8IUE6|H2A2B_HUMAN,sp|Q96QV6|H2A1A_HUMAN,sp|P0C0S5|H2AZ_HUMAN,sp|P04908|H2A1B_HUMAN,sp|P20671|H2A1D_HUMAN,sp|P0C0S8|H2A1_HUMAN,sp|Q6FI13|H2A2A_HUMAN,sp|Q96KK5|H2A1H_HUMAN,sp|Q71UI9|H2AV_HUMAN,sp|Q7L7L0|H2A3_HUMAN,tr|A0A0U1RR32|A0A0U1RR32_HUMAN,tr|A0A0U1RRH7|A0A0U1RRH7_HUMAN,tr|A0A3B3IS11|A0A3B3IS11_HUMAN,tr|C9J0D1|C9J0D1_HUMAN,tr|A0A494C189|A0A494C189_HUMAN" 20 953.5322 1.19 32073 16758 2 953.531774 477.7734 Histone H2AX OS=Homo sapiens OX=9606 GN=H2AX PE=1 SV=2 9.79 2965.2 - 8.95E+06 - - - -0.4677 - 1.596 0.163 - 405.3 1 2 0 -0.0004 9 0 0 0 9.15E+08 7.66E+08 - - - 1.5973 1 221125_WJC_METTL3_EV_vs_WT_F03.16760.16760.3 4.40E-07 13/44 R.ATLENDFVVLKK.D sp|Q8N1N4|K2C78_HUMAN 1 1375.7711 999 32075 16760 3 1375.770362 459.5976 "Keratin, type II cytoskeletal 78 OS=Homo sapiens OX=9606 GN=KRT78 PE=1 SV=2" 6.11 2965.3 - 2.27E+06 - - - -0.5488 - 2.609 0.556 - 210.8 1 2 0 -0.0008 12 0 0 0 5.87E+07 0.00E+00 - - - 7.3968 0.999 221125_WJC_METTL3_EV_vs_WT_F03.16761.16761.2 0.00467 16-Aug R.DMPYQPFSK[136.11].G "sp|O15371|EIF3D_HUMAN,tr|B0QYA8|B0QYA8_HUMAN,tr|B0QYA6|B0QYA6_HUMAN,tr|B0QYA5|B0QYA5_HUMAN" 4 1119.515 0.81 32076 16761 2 1119.515471 560.7648 Eukaryotic translation initiation factor 3 subunit D OS=Homo sapiens OX=9606 GN=EIF3D PE=1 SV=1 5.83 2965.4 - 2.01E+06 - - - 0.3921 - 1.367 0.337 - 256.2 1 2 0 0.0004 9 0 0 0 7.89E+07 9.78E+07 - - - 2.4344 0.9993 221125_WJC_METTL3_EV_vs_WT_F03.16762.16762.2 0.000285 12-Oct K.HVIDFFK[136.11].K sp|Q9NTZ6|RBM12_HUMAN 1 912.4949 1.56 32077 16762 2 912.49351 457.2547 RNA-binding protein 12 OS=Homo sapiens OX=9606 GN=RBM12 PE=1 SV=1 6.74 2965.5 - 1.90E+06 - - - -1.5112 - 2.02 0.251 - 477.1 1 2 0 -0.0014 7 0 0 0 4.04E+07 2.59E+07 - - - 3.1223 0.9406 221125_WJC_METTL3_EV_vs_WT_F03.16763.16763.2 0.16 22-Oct R.EIEVPDQYGTIR.A "sp|Q9HC35|EMAL4_HUMAN,tr|B5MBZ0|B5MBZ0_HUMAN" 2 1418.7042 0.56 32078 16763 2 1418.698026 710.3594 Echinoderm microtubule-associated protein-like 4 OS=Homo sapiens OX=9606 GN=EML4 PE=1 SV=3 4.14 2965.7 - 1.83E+06 - - - -4.323 - 1.155 0.222 - 130.8 1 2 0 -0.0061 12 0 0 0 1.29E+07 2.30E+07 - - - 1.0579 0.9987 221125_WJC_METTL3_EV_vs_WT_F03.16764.16764.3 0.00221 Dec-40 R.VC[160.03]EEIAIIPSK.K "sp|P08708|RS17_HUMAN,tr|H0YN73|H0YN73_HUMAN,tr|H3BNC9|H3BNC9_HUMAN,tr|H0YN88|H0YN88_HUMAN,tr|A0A075B716|A0A075B716_HUMAN" 5 1257.6639 1.33 32079 16764 3 1257.662079 420.2286 40S ribosomal protein S17 OS=Homo sapiens OX=9606 GN=RPS17 PE=1 SV=2 4.53 2965.7 - 1.34E+06 - - - -1.428 - 1.769 0.282 - 211.5 1 2 0 -0.0018 11 0 0 0 3.49E+07 2.63E+07 - - - 3.304 0.9993 221125_WJC_METTL3_EV_vs_WT_F03.16765.16765.3 0.00371 Dec-32 R.FSFWDKDAR.T "sp|P78406|RAE1L_HUMAN,tr|E9PQ57|E9PQ57_HUMAN" 2 1170.5458 1.72 32080 16765 3 1170.545128 391.1892 mRNA export factor OS=Homo sapiens OX=9606 GN=RAE1 PE=1 SV=1 5.96 2965.8 - 975714 - - - -0.5809 - 1.896 0.388 - 163.8 1 2 1 -0.0007 9 0 0 0 1.94E+08 1.13E+08 - - - 4.7937 0.9947 221125_WJC_METTL3_EV_vs_WT_F03.16766.16766.2 2.56E-06 28-Nov R.MGLAMGGGGGASFDR.A "sp|P52272|HNRPM_HUMAN,tr|M0R2I7|M0R2I7_HUMAN,tr|M0QY96|M0QY96_HUMAN,tr|A0A087X0X3|A0A087X0X3_HUMAN" 4 1382.6071 17.93 32081 16766 2 1383.611293 692.3108 Heterogeneous nuclear ribonucleoprotein M OS=Homo sapiens OX=9606 GN=HNRNPM PE=1 SV=3 5.59 2965.9 - 760792 - - - 726.3003 - 2.286 0.567 - 380.4 1 2 0 1.0042 15 0 0 0 3.90E+07 2.17E+06 - - - 4.9463 1 221125_WJC_METTL3_EV_vs_WT_F03.16768.16768.2 2.90E-10 14/26 R.VDLYQQASPPDALR[166.11].W sp|P48634|PRC2A_HUMAN 1 1581.8026 1.98 32083 16768 2 1581.799171 791.9086 Protein PRRC2A OS=Homo sapiens OX=9606 GN=PRRC2A PE=1 SV=3 4.21 2966.2 - 688707 - - - -2.1937 - 2.966 0.661 - 637.5 1 2 0 -0.0035 14 0 0 0 3.60E+07 1.81E+07 - - - 6.6504 0.9326 221125_WJC_METTL3_EV_vs_WT_F03.16774.16774.2 0.0344 20-Aug D.DLGEVLALSLR.A "sp|Q96BJ8|ELMO3_HUMAN,tr|F8W9E7|F8W9E7_HUMAN" 2 1184.6765 9.79 32087 16774 2 1184.677242 593.3455 Engulfment and cell motility protein 3 OS=Homo sapiens OX=9606 GN=ELMO3 PE=1 SV=3 4.37 2966.8 - 4.96E+06 - - - 0.6365 - 1.61 0.27 - 251.3 1 1 0 0.0008 11 0 0 0 5.60E+07 5.72E+06 - - - 2.3233 1 221125_WJC_METTL3_EV_vs_WT_F03.16775.16775.3 1.29E-08 20/60 K.FLC[160.03]ADYAEQDELDYHR[166.11].G "sp|Q9UKV3|ACINU_HUMAN,tr|G3V3B0|G3V3B0_HUMAN,tr|S4R3H4|S4R3H4_HUMAN,tr|E7EQT4|E7EQT4_HUMAN" 4 2053.8715 1.38 32088 16775 3 2053.872041 685.6311 Apoptotic chromatin condensation inducer in the nucleus OS=Homo sapiens OX=9606 GN=ACIN1 PE=1 SV=2 4.1 2966.9 - 3.18E+06 - - - 0.2507 - 2.983 0.523 - 473.7 1 2 0 0.0005 16 0 0 0 5.36E+07 3.88E+07 - - - 7.1751 1 221125_WJC_METTL3_EV_vs_WT_F03.16776.16776.3 5.67E-10 15/60 K.FLC[160.03]ADYAEQDELDYHR.G "sp|Q9UKV3|ACINU_HUMAN,tr|G3V3B0|G3V3B0_HUMAN,tr|S4R3H4|S4R3H4_HUMAN,tr|E7EQT4|E7EQT4_HUMAN" 4 2043.8633 1.39 32089 16776 3 2043.859061 682.295 Apoptotic chromatin condensation inducer in the nucleus OS=Homo sapiens OX=9606 GN=ACIN1 PE=1 SV=2 4.1 2967 - 3.16E+06 - - - -2.0525 - 2.886 0.637 - 244.6 1 2 0 -0.0042 16 0 0 0 5.40E+07 3.89E+07 - - - 8.3602 0.9992 221125_WJC_METTL3_EV_vs_WT_F03.16778.16778.2 0.0388 14-Jul R.VQFC[160.03]PFEK.N "sp|Q96EL3|RM53_HUMAN,tr|B9A051|B9A051_HUMAN" 2 1053.4954 1.06 32091 16778 2 1053.494646 527.755 "39S ribosomal protein L53, mitochondrial OS=Homo sapiens OX=9606 GN=MRPL53 PE=1 SV=1" 5.97 2967.1 - 2.28E+06 - - - -0.6711 - 1.441 0.333 - 266.9 1 2 0 -0.0007 8 0 0 0 7.62E+07 7.16E+07 - - - 2.6022 0.9974 221125_WJC_METTL3_EV_vs_WT_F03.16779.16779.2 0.369 14-Jul R.VQFC[160.03]PFEK[136.11].N "sp|Q96EL3|RM53_HUMAN,tr|B9A051|B9A051_HUMAN" 2 1061.5096 1.05 32092 16779 2 1061.50984 531.7621 "39S ribosomal protein L53, mitochondrial OS=Homo sapiens OX=9606 GN=MRPL53 PE=1 SV=1" 5.97 2967.2 - 2.20E+06 - - - 0.2704 - 1.532 0.173 - 181.9 1 2 0 0.0003 8 0 0 0 7.62E+07 7.27E+07 - - - 1.6052 0.9999 221125_WJC_METTL3_EV_vs_WT_F03.16780.16780.2 4.17E-07 15/26 R.SVGELPSTVESLQK.V sp|Q07065|CKAP4_HUMAN 1 1472.7722 1.22 32093 16780 2 1472.772809 737.3934 Cytoskeleton-associated protein 4 OS=Homo sapiens OX=9606 GN=CKAP4 PE=1 SV=2 4.53 2967.3 - 1.88E+06 - - - 0.387 - 2.761 0.461 - 629.1 1 2 0 0.0006 14 0 0 0 5.23E+07 4.28E+07 - - - 4.9943 1 221125_WJC_METTL3_EV_vs_WT_F03.16781.16781.2 2.34E-10 18/30 K.IFVGNVSAAC[160.03]TSQELR[166.11].S "sp|Q96PK6|RBM14_HUMAN,tr|B8ZZ74|B8ZZ74_HUMAN,tr|F8WDX3|F8WDX3_HUMAN,tr|A0A0A0MSL8|A0A0A0MSL8_HUMAN,tr|A0A0A6YYI9|A0A0A6YYI9_HUMAN" 5 1760.8755 1.69 32094 16781 2 1760.871611 881.445 RNA-binding protein 14 OS=Homo sapiens OX=9606 GN=RBM14 PE=1 SV=2 5.99 2967.4 - 1.47E+06 - - - -2.2023 - 3.162 0.624 - 946.3 1 2 0 -0.0039 16 0 0 0 1.47E+09 8.67E+08 - - - 6.4789 0.9946 221125_WJC_METTL3_EV_vs_WT_F03.16782.16782.3 1.25E-05 19/72 A.AAAAAAAAVTAASTSYYGR.D "sp|Q9BWF3|RBM4_HUMAN,tr|E9PB51|E9PB51_HUMAN" 2 1742.8588 0.04 32095 16782 3 1742.854546 581.9602 RNA-binding protein 4 OS=Homo sapiens OX=9606 GN=RBM4 PE=1 SV=1 8.63 2967.5 - 867951 - - - -2.4196 - 3.563 0.476 - 614.9 1 1 0 -0.0042 19 0 0 0 1.07E+07 2.60E+08 - - - 6.9674 1 221125_WJC_METTL3_EV_vs_WT_F03.16783.16783.2 4.84E-09 14/24 R.VYNASSTIVPSLK[136.11].H "sp|Q9NRG9|AAAS_HUMAN,tr|H3BU82|H3BU82_HUMAN,tr|F8VZ44|F8VZ44_HUMAN" 3 1385.7646 1.56 32096 16783 2 1385.764251 693.8896 Aladin OS=Homo sapiens OX=9606 GN=AAAS PE=1 SV=1 8.56 2967.7 - 696862 - - - -0.2381 - 2.558 0.654 - 594.5 1 2 0 -0.0003 13 0 0 0 2.65E+07 1.70E+07 - - - 6.2819 0.9981 221125_WJC_METTL3_EV_vs_WT_F03.16786.16786.2 0.359 16-Aug R.AGLQFPVGR.V "sp|P16104|H2AX_HUMAN,sp|Q9BTM1|H2AJ_HUMAN,sp|Q93077|H2A1C_HUMAN,sp|Q99878|H2A1J_HUMAN,sp|Q16777|H2A2C_HUMAN,sp|Q8IUE6|H2A2B_HUMAN,sp|Q96QV6|H2A1A_HUMAN,sp|P0C0S5|H2AZ_HUMAN,sp|P04908|H2A1B_HUMAN,sp|P20671|H2A1D_HUMAN,sp|P0C0S8|H2A1_HUMAN,sp|Q6FI13|H2A2A_HUMAN,sp|Q96KK5|H2A1H_HUMAN,sp|Q71UI9|H2AV_HUMAN,sp|Q7L7L0|H2A3_HUMAN,tr|A0A0U1RR32|A0A0U1RR32_HUMAN,tr|A0A0U1RRH7|A0A0U1RRH7_HUMAN,tr|A0A3B3IS11|A0A3B3IS11_HUMAN,tr|C9J0D1|C9J0D1_HUMAN,tr|A0A494C189|A0A494C189_HUMAN" 20 943.524 1.19 32097 16786 2 943.522827 472.7693 Histone H2AX OS=Homo sapiens OX=9606 GN=H2AX PE=1 SV=2 9.79 2968.1 - 2.04E+07 - - - -1.1902 - 1.519 0.245 - 212.4 1 2 0 -0.0011 9 0 0 0 9.15E+08 7.66E+08 - - - 2.0597 1 221125_WJC_METTL3_EV_vs_WT_F03.16787.16787.2 1.49E-10 17/30 K.IFVGNVSAAC[160.03]TSQELR.S "sp|Q96PK6|RBM14_HUMAN,tr|B8ZZ74|B8ZZ74_HUMAN,tr|F8WDX3|F8WDX3_HUMAN,tr|A0A0A0MSL8|A0A0A0MSL8_HUMAN,tr|A0A0A6YYI9|A0A0A6YYI9_HUMAN" 5 1750.8672 1.69 32098 16787 2 1750.864222 876.4409 RNA-binding protein 14 OS=Homo sapiens OX=9606 GN=RBM14 PE=1 SV=2 5.99 2968.1 - 5.48E+06 - - - -1.7117 - 3.278 0.672 - 730.3 1 2 0 -0.003 16 0 0 0 1.47E+09 8.67E+08 - - - 6.9223 0.9996 221125_WJC_METTL3_EV_vs_WT_F03.16788.16788.3 0.000178 Dec-32 R.FSFWDK[136.11]DAR[166.11].T "sp|P78406|RAE1L_HUMAN,tr|E9PQ57|E9PQ57_HUMAN" 2 1188.5683 1.72 32099 16788 3 1188.566647 397.1967 mRNA export factor OS=Homo sapiens OX=9606 GN=RAE1 PE=1 SV=1 5.96 2968.2 - 4.05E+06 - - - -1.3722 - 2.034 0.441 - 143.9 1 2 1 -0.0016 9 0 0 0 1.94E+08 1.13E+08 - - - 5.5961 1 221125_WJC_METTL3_EV_vs_WT_F03.16789.16789.3 1.86E-06 16/60 K.IFVGNVSAAC[160.03]TSQELR[166.11].S "sp|Q96PK6|RBM14_HUMAN,tr|B8ZZ74|B8ZZ74_HUMAN,tr|F8WDX3|F8WDX3_HUMAN,tr|A0A0A0MSL8|A0A0A0MSL8_HUMAN,tr|A0A0A6YYI9|A0A0A6YYI9_HUMAN" 5 1760.8755 1.73 32100 16789 3 1760.874835 587.9658 RNA-binding protein 14 OS=Homo sapiens OX=9606 GN=RBM14 PE=1 SV=2 5.99 2968.2 - 2.58E+06 - - - -0.3714 - 3.208 0.507 - 383 1 2 0 -0.0007 16 0 0 0 6.50E+08 3.75E+08 - - - 7.1833 1 221125_WJC_METTL3_EV_vs_WT_F03.16790.16790.2 5.75E-09 15/26 K.ASAAFSSVGSVITK.K "sp|P55327|TPD52_HUMAN,tr|H0YC42|H0YC42_HUMAN" 2 1323.7034 999 32101 16790 2 1323.706507 662.859 Tumor protein D52 OS=Homo sapiens OX=9606 GN=TPD52 PE=1 SV=2 8.8 2968.3 - 2.37E+06 - - - 2.3238 - 3.024 0.611 - 849.3 1 2 0 0.0031 14 0 0 0 4.51E+07 0.00E+00 - - - 6.3298 0.9998 221125_WJC_METTL3_EV_vs_WT_F03.16791.16791.2 5.75E-05 18-Nov R.YGSDIVPFSK[136.11].V sp|P13010|XRCC5_HUMAN 1 1119.5692 0.74 32102 16791 2 1119.56855 560.7919 X-ray repair cross-complementing protein 5 OS=Homo sapiens OX=9606 GN=XRCC5 PE=1 SV=3 5.83 2968.4 - 2.31E+06 - - - -0.5591 - 1.98 0.451 - 275.3 1 2 0 -0.0006 10 0 0 0 4.44E+07 5.98E+07 - - - 4.2786 1 221125_WJC_METTL3_EV_vs_WT_F03.16798.16798.3 5.61E-09 16/60 K.IFVGNVSAAC[160.03]TSQELR.S "sp|Q96PK6|RBM14_HUMAN,tr|B8ZZ74|B8ZZ74_HUMAN,tr|F8WDX3|F8WDX3_HUMAN,tr|A0A0A0MSL8|A0A0A0MSL8_HUMAN,tr|A0A0A6YYI9|A0A0A6YYI9_HUMAN" 5 1750.8672 1.73 32107 16798 3 1750.865345 584.6297 RNA-binding protein 14 OS=Homo sapiens OX=9606 GN=RBM14 PE=1 SV=2 5.99 2969.3 - 8.58E+06 - - - -1.0703 - 3.033 0.609 - 432.6 1 2 0 -0.0019 16 0 0 0 6.50E+08 3.75E+08 - - - 8.1762 1 221125_WJC_METTL3_EV_vs_WT_F03.16801.16801.3 4.68E-07 22/52 K.QIGNVAALPGIVHR.S sp|Q9Y3I0|RTCB_HUMAN 1 1443.831 1.47 32110 16801 3 1443.830043 482.2843 RNA-splicing ligase RtcB homolog OS=Homo sapiens OX=9606 GN=RTCB PE=1 SV=1 9.76 2969.5 - 2.41E+06 - - - -0.685 - 3.373 0.521 - 660.2 1 2 0 -0.001 14 0 0 0 8.67E+07 5.88E+07 - - - 7.5794 0.9999 221125_WJC_METTL3_EV_vs_WT_F03.16802.16802.2 1.25E-05 18-Nov R.YGSDIVPFSK.V sp|P13010|XRCC5_HUMAN 1 1111.555 0.76 32111 16802 2 1111.553915 556.7848 X-ray repair cross-complementing protein 5 OS=Homo sapiens OX=9606 GN=XRCC5 PE=1 SV=3 5.83 2969.5 - 2.20E+06 - - - -0.9545 - 2.051 0.588 - 367.1 1 2 0 -0.0011 10 0 0 0 4.44E+07 5.84E+07 - - - 5.3887 0.9996 221125_WJC_METTL3_EV_vs_WT_F03.16804.16804.2 0.122 16-Oct R.IDISPSTFR[166.11].K "sp|Q9Y2W1|TR150_HUMAN,tr|A0A3B3ITZ9|A0A3B3ITZ9_HUMAN" 2 1044.5479 2.25 32113 16804 2 1044.546496 523.2812 Thyroid hormone receptor-associated protein 3 OS=Homo sapiens OX=9606 GN=THRAP3 PE=1 SV=2 5.84 2969.8 - 1.60E+06 - - - -1.3728 - 2.247 0.303 - 229.7 1 2 0 -0.0014 9 0 0 0 2.96E+08 1.32E+08 - - - 3.6207 0.9919 221125_WJC_METTL3_EV_vs_WT_F03.16810.16810.3 2.05E-06 17/56 A.GVMAIEHADFAGVER[166.11].L "sp|P78371|TCPB_HUMAN,tr|F8VQ14|F8VQ14_HUMAN,tr|F5GWF6|F5GWF6_HUMAN" 3 1610.775 0.08 32117 16810 3 1610.769851 537.9323 T-complex protein 1 subunit beta OS=Homo sapiens OX=9606 GN=CCT2 PE=1 SV=4 4.65 2970.4 - 3.79E+06 - - - -3.2252 - 3.203 0.51 - 343.5 1 1 0 -0.0052 15 0 0 0 5.95E+06 7.24E+07 - - - 7.2621 1 221125_WJC_METTL3_EV_vs_WT_F03.16811.16811.2 8.37E-08 15/26 R.SVGELPSTVESLQK[136.11].V sp|Q07065|CKAP4_HUMAN 1 1480.7864 1.11 32118 16811 2 1480.78648 741.4005 Cytoskeleton-associated protein 4 OS=Homo sapiens OX=9606 GN=CKAP4 PE=1 SV=2 4.53 2970.6 - 1.71E+06 - - - 0.0277 - 2.803 0.581 - 628.5 1 2 0 0 14 0 0 0 5.41E+07 4.86E+07 - - - 5.9187 0.998 221125_WJC_METTL3_EV_vs_WT_F03.16813.16813.2 0.00016 12-Nov K.HVIDFFK.K sp|Q9NTZ6|RBM12_HUMAN 1 904.4807 1.18 32120 16813 2 904.478265 453.2476 RNA-binding protein 12 OS=Homo sapiens OX=9606 GN=RBM12 PE=1 SV=1 6.74 2970.8 - 1.50E+06 - - - -2.68 - 2.141 0.193 - 489.1 1 2 0 -0.0024 7 0 0 0 2.96E+07 2.51E+07 - - - 2.8779 1 221125_WJC_METTL3_EV_vs_WT_F03.16814.16814.2 9.17E-09 14/26 K.IVLTNPVC[160.03]TEVGEK.L "sp|Q2VIR3|IF2GL_HUMAN,sp|P41091|IF2G_HUMAN" 2 1557.8072 1.09 32121 16814 2 1557.802804 779.9109 Eukaryotic translation initiation factor 2 subunit 3B OS=Homo sapiens OX=9606 GN=EIF2S3B PE=2 SV=2 4.53 2970.9 - 1.19E+06 - - - -2.8502 - 2.944 0.539 - 579.5 1 2 0 -0.0044 14 0 0 0 1.68E+08 1.54E+08 - - - 5.7303 0.9998 221125_WJC_METTL3_EV_vs_WT_F03.16821.16821.2 1.07E-06 14/26 K.IVLTNPVC[160.03]TEVGEK[136.11].L "sp|Q2VIR3|IF2GL_HUMAN,sp|P41091|IF2G_HUMAN" 2 1565.8214 1.13 32126 16821 2 1565.824131 783.918 Eukaryotic translation initiation factor 2 subunit 3B OS=Homo sapiens OX=9606 GN=EIF2S3B PE=2 SV=2 4.53 2971.8 - 1.80E+06 - - - 1.716 - 2.677 0.537 - 273.7 1 2 0 0.0027 14 0 0 0 1.74E+08 1.54E+08 - - - 5.4775 0.9999 221125_WJC_METTL3_EV_vs_WT_F03.16825.16825.2 0.000438 22-Dec R.TVIIEQSWGSPK.V "sp|P10809|CH60_HUMAN,tr|C9JL25|C9JL25_HUMAN,tr|A0A7I2V2X6|A0A7I2V2X6_HUMAN,tr|A0A7I2YQK6|A0A7I2YQK6_HUMAN,tr|A0A7I2V599|A0A7I2V599_HUMAN,tr|E7EXB4|E7EXB4_HUMAN,tr|C9JL19|C9JL19_HUMAN,tr|A0A7I2YQ71|A0A7I2YQ71_HUMAN,tr|E7ESH4|E7ESH4_HUMAN,tr|A0A7I2V5M1|A0A7I2V5M1_HUMAN,tr|A0A7I2V5K3|A0A7I2V5K3_HUMAN,tr|A0A7I2V369|A0A7I2V369_HUMAN,tr|C9JCQ4|C9JCQ4_HUMAN" 13 1343.7085 1.27 32129 16825 2 1343.707147 672.8615 "60 kDa heat shock protein, mitochondrial OS=Homo sapiens OX=9606 GN=HSPD1 PE=1 SV=2" 5.66 2972.2 - 4.68E+06 - - - -1.0188 - 2.551 0.449 - 465.4 1 2 0 -0.0014 12 0 0 0 1.62E+10 1.28E+10 - - - 4.8209 0.9999 221125_WJC_METTL3_EV_vs_WT_F03.16826.16826.2 4.00E-06 14/22 R.TVIIEQSWGSPK[136.11].V "sp|P10809|CH60_HUMAN,tr|C9JL25|C9JL25_HUMAN,tr|A0A7I2V2X6|A0A7I2V2X6_HUMAN,tr|A0A7I2YQK6|A0A7I2YQK6_HUMAN,tr|A0A7I2V599|A0A7I2V599_HUMAN,tr|E7EXB4|E7EXB4_HUMAN,tr|C9JL19|C9JL19_HUMAN,tr|A0A7I2YQ71|A0A7I2YQ71_HUMAN,tr|E7ESH4|E7ESH4_HUMAN,tr|A0A7I2V5M1|A0A7I2V5M1_HUMAN,tr|A0A7I2V5K3|A0A7I2V5K3_HUMAN,tr|A0A7I2V369|A0A7I2V369_HUMAN,tr|C9JCQ4|C9JCQ4_HUMAN" 13 1351.7227 1.27 32130 16826 2 1351.721589 676.8686 "60 kDa heat shock protein, mitochondrial OS=Homo sapiens OX=9606 GN=HSPD1 PE=1 SV=2" 5.66 2972.3 - 3.42E+06 - - - -0.8338 - 2.812 0.503 - 652.9 1 2 0 -0.0011 12 0 0 0 1.62E+10 1.28E+10 - - - 5.4762 0.9997 221125_WJC_METTL3_EV_vs_WT_F03.16828.16828.2 2.17E-05 13/22 K.TSSVFEDPVISK[136.11].F "sp|Q9Y2R9|RT07_HUMAN,tr|J3QKW2|J3QKW2_HUMAN,tr|J3QLS3|J3QLS3_HUMAN,tr|J3QQS1|J3QQS1_HUMAN" 4 1315.6751 0.8 32132 16828 2 1315.672415 658.8448 "28S ribosomal protein S7, mitochondrial OS=Homo sapiens OX=9606 GN=MRPS7 PE=1 SV=2" 4.37 2972.4 - 3.24E+06 - - - -2.0385 - 2.419 0.486 - 338.3 1 2 0 -0.0027 12 0 0 0 7.61E+07 9.48E+07 - - - 4.954 0.9991 221125_WJC_METTL3_EV_vs_WT_F03.16832.16832.2 2.07E-06 20-Nov R.WAQEDLLEEQK.D sp|O75528|TADA3_HUMAN 1 1387.662 0.01 32136 16832 2 1387.656186 694.8383 Transcriptional adapter 3 OS=Homo sapiens OX=9606 GN=TADA3 PE=1 SV=1 4 2972.9 - 792511 - - - -4.161 - 2.698 0.539 - 366.3 1 2 0 -0.0058 11 0 0 0 1.45E+07 1.92E+09 - - - 5.7052 0.9868 221125_WJC_METTL3_EV_vs_WT_F03.16837.16837.2 5.82E-07 13/24 R.SLPFSENVSAVQK[136.11].L "sp|Q16513|PKN2_HUMAN,tr|B1AL79|B1AL79_HUMAN" 2 1412.7391 1.09 32139 16837 2 1412.727577 707.3768 Serine\threonine-protein kinase N2 OS=Homo sapiens OX=9606 GN=PKN2 PE=1 SV=1 5.72 2973.5 - 1.77E+06 - - - -8.153 - 2.338 0.552 - 521 1 2 0 -0.0115 13 0 0 0 3.12E+07 2.86E+07 - - - 5.2942 0.9898 221125_WJC_METTL3_EV_vs_WT_F03.16840.16840.2 0.302 16-Aug K.DLSLEEIQK[136.11].K "sp|P16949|STMN1_HUMAN,sp|Q93045|STMN2_HUMAN,tr|E5RGX5|E5RGX5_HUMAN,tr|A2A2D0|A2A2D0_HUMAN" 4 1081.5747 0.86 32142 16840 2 1081.573955 541.7946 Stathmin OS=Homo sapiens OX=9606 GN=STMN1 PE=1 SV=3 4.14 2973.8 - 1.17E+06 - - - -0.6472 - 1.359 0.097 - 145.3 1 2 0 -0.0007 9 0 0 0 3.72E+07 4.34E+07 - - - 0.6447 0.9999 221125_WJC_METTL3_EV_vs_WT_F03.16844.16844.3 1.16E-06 18/68 R.VAPEEHPVLLTEAPLNPK[136.11].A "sp|P63261|ACTG_HUMAN,sp|P60709|ACTB_HUMAN,tr|A0A804GS07|A0A804GS07_HUMAN,tr|I3L3I0|I3L3I0_HUMAN,tr|G5E9R0|G5E9R0_HUMAN,tr|E7EVS6|E7EVS6_HUMAN,tr|A0A6Q8PFE4|A0A6Q8PFE4_HUMAN,tr|J3KT65|J3KT65_HUMAN,tr|I3L3R2|I3L3R2_HUMAN,tr|K7EM38|K7EM38_HUMAN,tr|A0A6Q8PH58|A0A6Q8PH58_HUMAN,tr|I3L1U9|I3L1U9_HUMAN,tr|A0A2R8Y793|A0A2R8Y793_HUMAN,tr|I3L4N8|I3L4N8_HUMAN,tr|A0A2R8YGF8|A0A2R8YGF8_HUMAN" 15 1961.0713 1.09 32143 16844 3 1961.065208 654.6977 "Actin, cytoplasmic 2 OS=Homo sapiens OX=9606 GN=ACTG1 PE=1 SV=1" 4.75 2974.4 - 3.04E+06 - - - -3.1207 - 2.967 0.515 - 372.3 1 2 0 -0.0061 18 0 0 0 2.98E+08 2.73E+08 - - - 6.9882 0.9999 221125_WJC_METTL3_EV_vs_WT_F03.16846.16846.3 0.00913 Dec-40 K.IHPQTIIAGWR.E "sp|P78371|TCPB_HUMAN,tr|F8VQ14|F8VQ14_HUMAN,tr|F5GWF6|F5GWF6_HUMAN" 3 1290.7197 0.5 32145 16846 3 1290.717693 431.2472 T-complex protein 1 subunit beta OS=Homo sapiens OX=9606 GN=CCT2 PE=1 SV=4 9.76 2974.5 - 8.39E+06 - - - -1.5472 - 2.169 0.408 - 257.5 1 2 0 -0.002 11 0 0 0 2.94E+08 5.93E+08 - - - 5.2878 0.9995 221125_WJC_METTL3_EV_vs_WT_F03.16852.16852.2 4.51E-07 15/30 R.TLTAAAVSGAQPILSK.L "sp|O60664|PLIN3_HUMAN,tr|K7EL96|K7EL96_HUMAN,tr|K7ER39|K7ER39_HUMAN" 3 1526.8668 2.18 32149 16852 2 1526.871698 764.4407 Perilipin-3 OS=Homo sapiens OX=9606 GN=PLIN3 PE=1 SV=3 8.41 2975.3 - 1.46E+06 - - - 3.2026 - 3.013 0.481 - 595.1 1 2 0 0.0049 16 0 0 0 3.89E+07 1.78E+07 - - - 5.3037 1 221125_WJC_METTL3_EV_vs_WT_F03.16853.16853.3 0.000333 20/44 R.YLRPPNTSLFVR.N "sp|O75494|SRS10_HUMAN,tr|Q5JRI1|Q5JRI1_HUMAN,tr|Q6IQ42|Q6IQ42_HUMAN,tr|R4GMP8|R4GMP8_HUMAN" 4 1461.8092 1.99 32150 16853 3 1461.809844 488.277 Serine\arginine-rich splicing factor 10 OS=Homo sapiens OX=9606 GN=SRSF10 PE=1 SV=1 10.84 2975.4 - 1.66E+06 - - - 0.418 - 2.919 0.494 - 329.2 1 2 0 0.0006 12 0 0 0 4.57E+07 2.29E+07 - - - 7.0168 0.998 221125_WJC_METTL3_EV_vs_WT_F03.16854.16854.2 0.00188 16-Jul K.GHLAFLSGQ.- "sp|O95639|CPSF4_HUMAN,tr|B7Z7B0|B7Z7B0_HUMAN,tr|C9JEV9|C9JEV9_HUMAN" 3 928.4767 - 32151 16854 2 928.474694 465.2456 Cleavage and polyadenylation specificity factor subunit 4 OS=Homo sapiens OX=9606 GN=CPSF4 PE=1 SV=1 6.74 2975.5 - 1.57E+06 - - - -2.1239 - 1.715 0.262 - 208.9 1 2 0 -0.002 9 0 0 0 - - - - - 2.5361 0.9997 221125_WJC_METTL3_EV_vs_WT_F03.16859.16859.2 0.000121 24-Dec K.DEILPTTPISEQK[136.11].G "sp|P23396|RS3_HUMAN,tr|H0YEU2|H0YEU2_HUMAN,tr|E9PSF4|E9PSF4_HUMAN,tr|E9PL09|E9PL09_HUMAN,tr|E9PPU1|E9PPU1_HUMAN" 5 1477.7755 0.62 32154 16859 2 1477.777183 739.895 40S ribosomal protein S3 OS=Homo sapiens OX=9606 GN=RPS3 PE=1 SV=2 4.14 2976.1 - 2.31E+06 - - - 1.1118 - 2.135 0.382 - 357.7 1 2 0 0.0016 13 0 0 0 4.63E+07 7.42E+07 - - - 3.8086 0.9742 221125_WJC_METTL3_EV_vs_WT_F03.16860.16860.2 1.20E-06 14/24 K.FLADQQSEIDGLK[136.11].G "sp|P12270|TPR_HUMAN,tr|Q5SWX9|Q5SWX9_HUMAN" 2 1470.7446 3.4 32155 16860 2 1470.753547 736.3796 Nucleoprotein TPR OS=Homo sapiens OX=9606 GN=TPR PE=1 SV=3 4.03 2976.3 - 1.91E+06 - - - 6.101 - 2.327 0.214 - 536.5 1 2 0 0.009 13 0 0 0 1.20E+08 3.54E+07 - - - 2.7864 0.9989 221125_WJC_METTL3_EV_vs_WT_F03.16863.16863.2 0.017 24-Sep K.AVSISTEPPTYLR.E "sp|Q12824|SNF5_HUMAN,tr|A0A2R8Y5N5|A0A2R8Y5N5_HUMAN,tr|A0A2R8YEE8|A0A2R8YEE8_HUMAN,tr|A0A0U1RQQ2|A0A0U1RQQ2_HUMAN,tr|C9JTA6|C9JTA6_HUMAN,tr|A0A0U1RRB8|A0A0U1RRB8_HUMAN,tr|G5E975|G5E975_HUMAN,tr|A0A0G2JSE9|A0A0G2JSE9_HUMAN" 8 1432.7562 1.12 32156 16863 2 1432.757137 717.3854 SWI\SNF-related matrix-associated actin-dependent regulator of chromatin subfamily B member 1 OS=Homo sapiens OX=9606 GN=SMARCB1 PE=1 SV=2 6.05 2976.7 - 1.55E+06 - - - 0.6575 - 1.513 0.314 - 153.4 1 2 0 0.0009 13 0 0 0 3.98E+07 3.55E+07 - - - 2.4227 0.9996 221125_WJC_METTL3_EV_vs_WT_F03.16864.16864.2 0.00262 20-Nov R.TSWTSLSTIQK.L "sp|Q9Y2W6|TDRKH_HUMAN,tr|F6TB26|F6TB26_HUMAN,tr|B7ZAG4|B7ZAG4_HUMAN,tr|E9PQX4|E9PQX4_HUMAN,tr|E9PKN8|E9PKN8_HUMAN,tr|Q5SZR4|Q5SZR4_HUMAN" 6 1250.6507 0.04 32157 16864 2 1250.649783 626.3326 Tudor and KH domain-containing protein OS=Homo sapiens OX=9606 GN=TDRKH PE=1 SV=2 8.41 2976.8 - 1.09E+06 - - - -0.7068 - 1.727 0.366 - 354 1 2 0 -0.0009 11 0 0 0 2.24E+07 5.82E+08 - - - 3.2221 0.9996 221125_WJC_METTL3_EV_vs_WT_F03.16866.16866.2 0.00494 16-Nov R.NDVAWNFEK[136.11].F "sp|P07203|GPX1_HUMAN,tr|A0A2R8Y6B6|A0A2R8Y6B6_HUMAN" 2 1129.5284 1.94 32159 16866 2 1129.526223 565.7715 Glutathione peroxidase 1 OS=Homo sapiens OX=9606 GN=GPX1 PE=1 SV=4 4.37 2977.1 - 771829 - - - -1.9043 - 2.116 0.415 - 499 1 2 0 -0.0022 9 0 0 0 4.29E+07 2.21E+07 - - - 4.2739 1 221125_WJC_METTL3_EV_vs_WT_F03.16870.16870.2 1.58E-08 14/24 K.VYENYPTYDLTER.K "sp|P35659|DEK_HUMAN,tr|H0Y993|H0Y993_HUMAN,tr|A0A494C028|A0A494C028_HUMAN,tr|A0A494C198|A0A494C198_HUMAN,tr|B4DFG0|B4DFG0_HUMAN" 5 1661.7573 0.73 32161 16870 2 1661.754237 831.8859 Protein DEK OS=Homo sapiens OX=9606 GN=DEK PE=1 SV=1 4.14 2977.5 - 2.29E+06 - - - -1.8535 - 2.948 0.597 - 540 1 2 0 -0.0031 13 0 0 0 5.22E+07 7.14E+07 - - - 6.2242 0.9997 221125_WJC_METTL3_EV_vs_WT_F03.16872.16872.2 2.32E-05 16-Aug R.DYQELMNVK.L "sp|Q01546|K22O_HUMAN,sp|P12035|K2C3_HUMAN,sp|P35908|K22E_HUMAN,sp|Q5XKE5|K2C79_HUMAN,tr|H0YID6|H0YID6_HUMAN" 5 1138.5329 2959.79 32162 16872 2 1138.531365 570.2737 "Keratin, type II cytoskeletal 2 oral OS=Homo sapiens OX=9606 GN=KRT76 PE=1 SV=2" 4.37 2977.7 - 1.41E+06 - - - -1.3131 - 1.547 0.511 - 183 1 2 0 -0.0015 9 0 0 0 1.57E+09 5.31E+05 - - - 4.0771 0.9996 221125_WJC_METTL3_EV_vs_WT_F03.16874.16874.2 0.00724 16-Oct R.IDISPSTFR.K "sp|Q9Y2W1|TR150_HUMAN,tr|A0A3B3ITZ9|A0A3B3ITZ9_HUMAN" 2 1034.5397 2.22 32164 16874 2 1034.53846 518.2771 Thyroid hormone receptor-associated protein 3 OS=Homo sapiens OX=9606 GN=THRAP3 PE=1 SV=2 5.84 2977.9 - 1.09E+07 - - - -1.1599 - 2.078 0.34 - 311.6 1 2 0 -0.0012 9 0 0 0 3.02E+08 1.36E+08 - - - 3.6679 0.9848 221125_WJC_METTL3_EV_vs_WT_F03.16875.16875.3 0.422 Oct-36 R.VWDVR[166.11]PFAPK[136.11].E "sp|Q96DI7|SNR40_HUMAN,tr|Q9NSS8|Q9NSS8_HUMAN" 2 1231.6832 1.85 32165 16875 3 1231.68106 411.5684 U5 small nuclear ribonucleoprotein 40 kDa protein OS=Homo sapiens OX=9606 GN=SNRNP40 PE=1 SV=1 8.72 2978 - 1.07E+06 - - - -1.7764 - 1.592 0.172 - 175.5 1 2 0 -0.0022 10 0 0 0 9.14E+07 4.94E+07 - - - 1.815 0.9984 221125_WJC_METTL3_EV_vs_WT_F03.16876.16876.2 0.000901 14-Oct R.VQVWFQNR[166.11].R "sp|A6NJT0|UNC4_HUMAN,sp|Q96IS3|RAX2_HUMAN,sp|Q9Y2V3|RX_HUMAN,sp|O60902|SHOX2_HUMAN,sp|O15266|SHOX_HUMAN,sp|Q9H161|ALX4_HUMAN,sp|O95076|ALX3_HUMAN,sp|Q15699|ALX1_HUMAN,sp|A6NNA5|DRGX_HUMAN,sp|Q969G2|LHX4_HUMAN,sp|Q96QS3|ARX_HUMAN,sp|Q8N693|ESX1_HUMAN,sp|O14813|PHX2A_HUMAN,sp|Q99453|PHX2B_HUMAN,sp|Q9UBR4|LHX3_HUMAN,sp|Q99811|PRRX2_HUMAN,sp|Q5XKR4|OTP_HUMAN,sp|P54821|PRRX1_HUMAN,tr|A0A087WVB7|A0A087WVB7_HUMAN,tr|A6NLG4|A6NLG4_HUMAN,tr|A0A3B3IS30|A0A3B3IS30_HUMAN,tr|G3V2N3|G3V2N3_HUMAN,tr|F1T0D7|F1T0D7_HUMAN" 23 1085.5646 1.46 32166 16876 2 1085.568561 543.7896 Homeobox protein unc-4 homolog OS=Homo sapiens OX=9606 GN=UNCX PE=3 SV=1 9.72 2978.1 - 832281 - - - 3.6645 - 2.111 0.365 - 341 1 2 0 0.004 8 0 0 0 3.35E+07 2.30E+07 - - - 3.989 1 221125_WJC_METTL3_EV_vs_WT_F03.16879.16879.2 1.31E-10 15/24 K.VYENYPTYDLTER[166.11].K "sp|P35659|DEK_HUMAN,tr|H0Y993|H0Y993_HUMAN,tr|A0A494C028|A0A494C028_HUMAN,tr|A0A494C198|A0A494C198_HUMAN,tr|B4DFG0|B4DFG0_HUMAN" 5 1671.7656 0.73 32167 16879 2 1671.765085 836.8901 Protein DEK OS=Homo sapiens OX=9606 GN=DEK PE=1 SV=1 4.14 2978.5 - 3.42E+06 - - - -0.3003 - 3.013 0.657 - 661.4 1 2 0 -0.0005 13 0 0 0 5.22E+07 7.14E+07 - - - 6.7242 0.973 221125_WJC_METTL3_EV_vs_WT_F03.16880.16880.3 0.00426 15/40 K.FAAQELIEVK[136.11]R[166.11].G "sp|Q86U44|MTA70_HUMAN,tr|F5H6D8|F5H6D8_HUMAN,tr|H0YFV6|H0YFV6_HUMAN,tr|B4DTN4|B4DTN4_HUMAN" 4 1320.7521 9.19 32168 16880 3 1320.742864 441.258 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 6.14 2978.6 - 668148 - - - -6.9597 - 2.707 0.228 - 218.2 1 2 0 -0.0092 11 0 0 0 1.16E+08 1.26E+07 - - - 3.9084 0.9996 221125_WJC_METTL3_EV_vs_WT_F03.16884.16884.2 0.000169 16-Sep R.DQAWDDVVR.K sp|O00566|MPP10_HUMAN 1 1102.5043 0.57 32172 16884 2 1102.505936 552.2594 U3 small nucleolar ribonucleoprotein protein MPP10 OS=Homo sapiens OX=9606 GN=MPHOSPH10 PE=1 SV=2 3.93 2979.1 - 850341 - - - 1.4503 - 1.949 0.381 - 418.8 1 2 0 0.0016 9 0 0 0 1.44E+07 2.54E+07 - - - 3.7851 0.9999 221125_WJC_METTL3_EV_vs_WT_F03.16886.16886.3 0.00056 15/68 R.VAPEEHPVLLTEAPLNPK.A "sp|P63261|ACTG_HUMAN,sp|P60709|ACTB_HUMAN,tr|A0A804GS07|A0A804GS07_HUMAN,tr|I3L3I0|I3L3I0_HUMAN,tr|G5E9R0|G5E9R0_HUMAN,tr|E7EVS6|E7EVS6_HUMAN,tr|A0A6Q8PFE4|A0A6Q8PFE4_HUMAN,tr|J3KT65|J3KT65_HUMAN,tr|I3L3R2|I3L3R2_HUMAN,tr|K7EM38|K7EM38_HUMAN,tr|A0A6Q8PH58|A0A6Q8PH58_HUMAN,tr|I3L1U9|I3L1U9_HUMAN,tr|A0A2R8Y793|A0A2R8Y793_HUMAN,tr|I3L4N8|I3L4N8_HUMAN,tr|A0A2R8YGF8|A0A2R8YGF8_HUMAN" 15 1953.0571 1.09 32173 16886 3 1953.053611 652.0263 "Actin, cytoplasmic 2 OS=Homo sapiens OX=9606 GN=ACTG1 PE=1 SV=1" 4.75 2979.3 - 1.29E+07 - - - -1.8008 - 2.543 0.407 - 277.3 1 2 0 -0.0035 18 0 0 0 2.98E+08 2.73E+08 - - - 5.4008 0.999 221125_WJC_METTL3_EV_vs_WT_F03.16888.16888.2 1.80E-06 15/24 R.EAALEAAVLNK[136.11]EE.- "sp|Q9NZB2|F120A_HUMAN,tr|A0A0C4DG79|A0A0C4DG79_HUMAN" 2 1393.718 1.01 32174 16888 2 1393.718268 697.8663 Constitutive coactivator of PPAR-gamma-like protein 1 OS=Homo sapiens OX=9606 GN=FAM120A PE=1 SV=2 4.33 2979.5 - 1.86E+06 - - - 0.1744 - 2.756 0.521 - 781.5 1 2 1 0.0002 13 0 0 0 3.59E+07 3.55E+07 - - - 5.4909 0.9999 221125_WJC_METTL3_EV_vs_WT_F03.16889.16889.2 1.68E-05 24-Dec K.LSPVGWVSSSQGK.R "sp|Q00587|BORG5_HUMAN,tr|B0QYC6|B0QYC6_HUMAN,tr|B0QYC7|B0QYC7_HUMAN,tr|B0QYC8|B0QYC8_HUMAN" 4 1330.6881 0.91 32175 16889 2 1330.687966 666.3513 Cdc42 effector protein 1 OS=Homo sapiens OX=9606 GN=CDC42EP1 PE=1 SV=1 8.75 2979.6 - 1.86E+06 - - - -0.112 - 2.282 0.525 - 455.7 1 2 0 -0.0001 13 0 0 0 1.37E+08 1.51E+08 - - - 5.0361 1 221125_WJC_METTL3_EV_vs_WT_F03.16890.16890.2 4.88E-05 16/24 R.EAALEAAVLNKEE.- "sp|Q9NZB2|F120A_HUMAN,tr|A0A0C4DG79|A0A0C4DG79_HUMAN" 2 1385.7038 1.01 32176 16890 2 1385.702437 693.8592 Constitutive coactivator of PPAR-gamma-like protein 1 OS=Homo sapiens OX=9606 GN=FAM120A PE=1 SV=2 4.33 2979.7 - 2.36E+06 - - - -1.0017 - 3.128 0.531 - 945.4 1 2 1 -0.0014 13 0 0 0 3.59E+07 3.55E+07 - - - 5.8894 0.9762 221125_WJC_METTL3_EV_vs_WT_F03.16892.16892.2 0.00216 18-Dec K.EK[136.11]VDLVLLGK[136.11].Q sp|P38117|ETFB_HUMAN 1 1128.7089 1.93 32178 16892 2 1128.703852 565.3617 Electron transfer flavoprotein subunit beta OS=Homo sapiens OX=9606 GN=ETFB PE=1 SV=3 6.17 2979.9 - 833741 - - - -4.4821 - 2.145 0.432 - 453.5 1 2 1 -0.0051 10 0 0 0 1.87E+07 9.72E+06 - - - 4.3603 0.9999 221125_WJC_METTL3_EV_vs_WT_F03.16894.16894.3 0.000162 Dec-40 K.IHPQTIIAGWR[166.11].E "sp|P78371|TCPB_HUMAN,tr|F8VQ14|F8VQ14_HUMAN,tr|F5GWF6|F5GWF6_HUMAN" 3 1300.728 0.5 32179 16894 3 1300.726053 434.5833 T-complex protein 1 subunit beta OS=Homo sapiens OX=9606 GN=CCT2 PE=1 SV=4 9.76 2980.2 - 2.12E+07 - - - -1.4661 - 2.239 0.41 - 257.3 1 2 0 -0.0019 11 0 0 0 2.95E+08 5.95E+08 - - - 5.4004 0.9999 221125_WJC_METTL3_EV_vs_WT_F03.16895.16895.3 0.000361 13/52 K.FPSLLTHNENMVAK.V sp|P62906|RL10A_HUMAN 1 1599.8079 1.1 32180 16895 3 1599.806626 534.2766 60S ribosomal protein L10a OS=Homo sapiens OX=9606 GN=RPL10A PE=1 SV=2 6.75 2980.2 - 4.13E+06 - - - -0.8045 - 2.58 0.382 - 166.5 1 2 0 -0.0013 14 0 0 0 1.55E+08 1.40E+08 - - - 5.3173 0.9724 221125_WJC_METTL3_EV_vs_WT_F03.16896.16896.2 2.5 18-Jun R.AEDAEQEEGK[136.11].E "sp|Q8WW18|CQ050_HUMAN,tr|A0A075B7E2|A0A075B7E2_HUMAN" 2 1112.4713 0.001 32181 16896 2 1112.470959 557.2429 Uncharacterized protein C17orf50 OS=Homo sapiens OX=9606 GN=C17orf50 PE=1 SV=2 3.91 2980.3 - 2.28E+06 - - - -0.3173 - 0.982 0.148 - 71.2 2 2 0 -0.0004 10 0 0 0 0.00E+00 3.36E+08 - - - -0.0512 0.9999 221125_WJC_METTL3_EV_vs_WT_F03.16897.16897.2 3.45E-06 14/24 K.LSPVGWVSSSQGK[136.11].R "sp|Q00587|BORG5_HUMAN,tr|B0QYC6|B0QYC6_HUMAN,tr|B0QYC7|B0QYC7_HUMAN,tr|B0QYC8|B0QYC8_HUMAN" 4 1338.7023 0.86 32182 16897 2 1338.703764 670.3584 Cdc42 effector protein 1 OS=Homo sapiens OX=9606 GN=CDC42EP1 PE=1 SV=1 8.75 2980.4 - 1.97E+06 - - - 1.0824 - 2.265 0.565 - 512.8 1 2 0 0.0014 13 0 0 0 1.38E+08 1.60E+08 - - - 5.312 0.7692 221125_WJC_METTL3_EV_vs_WT_F03.16898.16898.2 0.211 26-Jul R.GLGVGFGSGGGSSS.S sp|P13647|K2C5_HUMAN 1 1124.5098 - 32183 16898 2 1124.509962 563.2622 "Keratin, type II cytoskeletal 5 OS=Homo sapiens OX=9606 GN=KRT5 PE=1 SV=3" 5.52 2980.6 - 1.59E+06 - - - 0.1298 - 1.22 0.213 - 102.6 1 1 0 0.0001 14 0 0 0 - - - - - 1.1132 1 221125_WJC_METTL3_EV_vs_WT_F03.16903.16903.2 6.30E-06 26-Dec R.VLNDSLTPEIEADR[166.11].S sp|Q9UI36|DACH1_HUMAN 1 1580.7921 2.16 32188 16903 2 1580.790371 791.4033 Dachshund homolog 1 OS=Homo sapiens OX=9606 GN=DACH1 PE=1 SV=4 3.92 2981.2 - 831809 - - - -1.1165 - 2.909 0.591 - 357.5 1 2 0 -0.0018 14 0 0 0 4.18E+08 1.93E+08 - - - 6.0852 0.9997 221125_WJC_METTL3_EV_vs_WT_F03.16904.16904.2 3.23E-05 18-Sep K.SYENELDPLK.N "sp|Q92878|RAD50_HUMAN,tr|E7EN38|E7EN38_HUMAN,tr|A0A494BZX5|A0A494BZX5_HUMAN,tr|A0A494C1B7|A0A494C1B7_HUMAN,tr|E7ESD9|E7ESD9_HUMAN,tr|A0A494C122|A0A494C122_HUMAN,tr|A0A494C0Y7|A0A494C0Y7_HUMAN,tr|A0A1W2PQ90|A0A1W2PQ90_HUMAN" 8 1206.5768 1.61 32189 16904 2 1206.577727 604.2957 DNA repair protein RAD50 OS=Homo sapiens OX=9606 GN=RAD50 PE=1 SV=1 4.14 2981.3 - 516189 - - - 0.7409 - 1.724 0.441 - 216.7 1 2 0 0.0009 10 0 0 0 2.47E+07 1.54E+07 - - - 3.8182 0.9994 221125_WJC_METTL3_EV_vs_WT_F03.16905.16905.2 0.0903 18-Jul R.VWDVR[166.11]PFAPK[136.11].E "sp|Q96DI7|SNR40_HUMAN,tr|Q9NSS8|Q9NSS8_HUMAN" 2 1231.6832 1.41 32190 16905 2 1231.682717 616.8489 U5 small nuclear ribonucleoprotein 40 kDa protein OS=Homo sapiens OX=9606 GN=SNRNP40 PE=1 SV=1 8.72 2981.4 - 406578 - - - -0.4311 - 1.571 0.336 - 144.8 1 2 0 -0.0005 10 0 0 0 5.64E+06 4.01E+06 - - - 2.7834 0.9998 221125_WJC_METTL3_EV_vs_WT_F03.16907.16907.2 0.00068 24-Dec K.FLADQQSEIDGLK.G "sp|P12270|TPR_HUMAN,tr|Q5SWX9|Q5SWX9_HUMAN" 2 1462.7304 3.42 32191 16907 2 1462.732727 732.3725 Nucleoprotein TPR OS=Homo sapiens OX=9606 GN=TPR PE=1 SV=3 4.03 2981.7 - 2.28E+06 - - - 1.6086 - 2.42 0.473 - 387.8 1 2 0 0.0024 13 0 0 0 1.21E+08 3.54E+07 - - - 4.8021 0.9999 221125_WJC_METTL3_EV_vs_WT_F03.16910.16910.2 5.64E-06 20-Dec R.FVMEVEVDGQK.F "sp|Q12906|ILF3_HUMAN,sp|Q96SI9|STRBP_HUMAN" 2 1279.6118 1.09 32193 16910 2 1279.610739 640.8132 Interleukin enhancer-binding factor 3 OS=Homo sapiens OX=9606 GN=ILF3 PE=1 SV=3 4.14 2982 - 3.16E+06 - - - -0.8596 - 2.403 0.545 - 418.2 1 2 0 -0.0011 11 0 0 0 1.56E+08 1.43E+08 - - - 5.4378 1 221125_WJC_METTL3_EV_vs_WT_F03.16911.16911.2 2.07E-06 16/26 R.VLNDSLTPEIEADR.S sp|Q9UI36|DACH1_HUMAN 1 1570.7839 2.17 32194 16911 2 1570.783064 786.3992 Dachshund homolog 1 OS=Homo sapiens OX=9606 GN=DACH1 PE=1 SV=4 3.92 2982 - 3.41E+06 - - - -0.5106 - 3.273 0.604 - 770.7 1 2 0 -0.0008 14 0 0 0 4.18E+08 1.92E+08 - - - 6.4774 0.9999 221125_WJC_METTL3_EV_vs_WT_F03.16914.16914.2 0.000137 14/26 K.LVLEQGDSSEILSK.K "sp|Q5VT06|CE350_HUMAN,tr|H0Y7F7|H0Y7F7_HUMAN" 2 1516.7985 3.9 32197 16914 2 1516.799993 759.4065 Centrosome-associated protein 350 OS=Homo sapiens OX=9606 GN=CEP350 PE=1 SV=1 4.14 2982.2 - 1.24E+06 - - - 1.0146 - 2.746 0.523 - 548.1 1 2 0 0.0015 14 0 0 0 1.37E+07 3.52E+06 - - - 5.4383 0.9999 221125_WJC_METTL3_EV_vs_WT_F03.16916.16916.3 8.63E-06 15/48 K.DFAAEVVHPGDLK[136.11].N "sp|P54577|SYYC_HUMAN,tr|A0A6Q8PFX2|A0A6Q8PFX2_HUMAN" 2 1404.7129 0.84 32199 16916 3 1404.71465 469.2449 "Tyrosine--tRNA ligase, cytoplasmic OS=Homo sapiens OX=9606 GN=YARS1 PE=1 SV=4" 4.54 2982.5 - 1.10E+06 - - - 1.26 - 2.237 0.459 - 215.5 1 2 0 0.0018 13 0 0 0 9.84E+06 1.17E+07 - - - 5.8399 0.9329 221125_WJC_METTL3_EV_vs_WT_F03.16917.16917.3 0.0734 14/40 K.VQR[166.11]EPLLTLVK[136.11].E sp|Q13200|PSMD2_HUMAN 1 1312.8197 0.31 32200 16917 3 1312.818308 438.6139 26S proteasome non-ATPase regulatory subunit 2 OS=Homo sapiens OX=9606 GN=PSMD2 PE=1 SV=3 8.72 2982.6 - 1.04E+06 - - - -1.0923 - 1.595 0.153 - 259.3 1 2 1 -0.0014 11 0 0 0 8.73E+06 2.77E+07 - - - 1.5717 0.9999 221125_WJC_METTL3_EV_vs_WT_F03.16918.16918.3 0.000674 13/48 R.EAMEHPYFYTVVK[136.11].D "sp|P68400|CSK21_HUMAN,sp|Q8NEV1|CSK23_HUMAN,tr|A0A2R8YFU2|A0A2R8YFU2_HUMAN,tr|A0A2R8YD58|A0A2R8YD58_HUMAN,tr|A0A2R8YF43|A0A2R8YF43_HUMAN,tr|A0A2R8Y5A0|A0A2R8Y5A0_HUMAN,tr|A0A087WY74|A0A087WY74_HUMAN,tr|A0A2R8YDP2|A0A2R8YDP2_HUMAN,tr|E7EU96|E7EU96_HUMAN" 9 1620.7738 1.64 32201 16918 3 1620.774066 541.2652 Casein kinase II subunit alpha OS=Homo sapiens OX=9606 GN=CSNK2A1 PE=1 SV=1 5.4 2982.7 - 835230 - - - 0.1851 - 2.273 0.426 - 206.6 1 2 0 0.0003 13 0 0 0 3.32E+07 2.03E+07 - - - 5.5156 0.9998 221125_WJC_METTL3_EV_vs_WT_F03.16920.16920.3 0.000111 Dec-40 R.LLFSHDLVSGR[166.11].Y sp|Q9C0C9|UBE2O_HUMAN 1 1252.6803 0.93 32203 16920 3 1252.678612 418.5674 (E3-independent) E2 ubiquitin-conjugating enzyme OS=Homo sapiens OX=9606 GN=UBE2O PE=1 SV=3 6.74 2983 - 741537 - - - -1.3802 - 2.176 0.37 - 231.2 1 2 0 -0.0017 11 0 0 0 1.33E+07 1.43E+07 - - - 4.8734 0.9955 221125_WJC_METTL3_EV_vs_WT_F03.16921.16921.3 0.0101 15/44 R.FLASVLHNGLGR.Y "sp|Q8N983|RM43_HUMAN,tr|M0R051|M0R051_HUMAN,tr|B1AL05|B1AL05_HUMAN,tr|H0Y6Y8|H0Y6Y8_HUMAN" 4 1282.7146 0.65 32204 16921 3 1282.714023 428.5788 "39S ribosomal protein L43, mitochondrial OS=Homo sapiens OX=9606 GN=MRPL43 PE=1 SV=1" 9.76 2983.1 - 740574 - - - -0.4537 - 1.989 0.166 - 201.7 1 2 0 -0.0006 12 0 0 0 5.50E+07 8.52E+07 - - - 2.2966 0.9959 221125_WJC_METTL3_EV_vs_WT_F03.16922.16922.2 1.52E-06 26-Dec K.LVLEQGDSSEILSK[136.11].K "sp|Q5VT06|CE350_HUMAN,tr|H0Y7F7|H0Y7F7_HUMAN" 2 1524.8127 3.9 32205 16922 2 1524.803196 763.4136 Centrosome-associated protein 350 OS=Homo sapiens OX=9606 GN=CEP350 PE=1 SV=1 4.14 2983.2 - 731529 - - - -6.2027 - 2.548 0.544 - 367.2 1 2 0 -0.0095 14 0 0 0 1.37E+07 3.52E+06 - - - 5.4031 0.9999 221125_WJC_METTL3_EV_vs_WT_F03.16926.16926.2 5.64E-07 18-Oct K.NLQEAEEWYK.S "sp|P08670|VIME_HUMAN,sp|P41219|PERI_HUMAN,tr|H7C5W5|H7C5W5_HUMAN,tr|F8W835|F8W835_HUMAN,tr|B0YJC5|B0YJC5_HUMAN,tr|B0YJC4|B0YJC4_HUMAN" 6 1308.5986 1.92 32207 16926 2 1308.598743 655.3066 Vimentin OS=Homo sapiens OX=9606 GN=VIM PE=1 SV=4 4.25 2983.8 - 7.50E+07 - - - 0.0848 - 2.01 0.528 - 323.6 1 2 0 0.0001 10 0 0 0 2.90E+09 1.51E+09 - - - 4.8895 0.9999 221125_WJC_METTL3_EV_vs_WT_F03.16927.16927.2 4.55E-06 18-Sep K.NLQEAEEWYK[136.11].S "sp|P08670|VIME_HUMAN,sp|P41219|PERI_HUMAN,tr|H7C5W5|H7C5W5_HUMAN,tr|F8W835|F8W835_HUMAN,tr|B0YJC5|B0YJC5_HUMAN,tr|B0YJC4|B0YJC4_HUMAN" 6 1316.6128 1.92 32208 16927 2 1316.612191 659.3137 Vimentin OS=Homo sapiens OX=9606 GN=VIM PE=1 SV=4 4.25 2983.8 - 3.95E+07 - - - -0.4869 - 1.873 0.571 - 254.5 1 2 0 -0.0006 10 0 0 0 2.90E+09 1.51E+09 - - - 5.0099 0.9992 221125_WJC_METTL3_EV_vs_WT_F03.16928.16928.2 0.406 14-Oct K.WSLLQQQK.T "sp|P05787|K2C8_HUMAN,tr|F8VUG2|F8VUG2_HUMAN,tr|F8VP67|F8VP67_HUMAN,tr|F8W1U3|F8W1U3_HUMAN" 4 1029.5607 2.06 32209 16928 2 1029.560584 515.7876 "Keratin, type II cytoskeletal 8 OS=Homo sapiens OX=9606 GN=KRT8 PE=1 SV=7" 8.75 2983.8 - 5.66E+06 - - - -0.1418 - 1.744 0.256 - 351.1 1 2 0 -0.0001 8 0 0 0 8.71E+07 4.23E+07 - - - 2.6092 1 221125_WJC_METTL3_EV_vs_WT_F03.16930.16930.2 1.70E-08 16/34 R.AIGGGLSSVGGGSSTIKY.T "sp|P48668|K2C6C_HUMAN,sp|P02538|K2C6A_HUMAN" 2 1609.8312 999 32211 16930 2 1609.831646 805.9229 "Keratin, type II cytoskeletal 6C OS=Homo sapiens OX=9606 GN=KRT6C PE=1 SV=3" 8.63 2983.9 - 3.69E+06 - - - 0.3075 - 3.008 0.552 - 629.2 1 1 0 0.0005 18 0 0 0 5.60E+07 0.00E+00 - - - 5.8255 0.9999 221125_WJC_METTL3_EV_vs_WT_F03.16931.16931.2 5.02E-07 14/24 R.GLPWSC[160.03]SADEVQR.F "sp|P31943|HNRH1_HUMAN,tr|E7EQJ0|E7EQJ0_HUMAN,tr|D6R9D3|D6R9D3_HUMAN,tr|D6RIH9|D6RIH9_HUMAN,tr|D6RJ04|D6RJ04_HUMAN,tr|E5RGV0|E5RGV0_HUMAN,tr|D6RFM3|D6RFM3_HUMAN,tr|E9PCY7|E9PCY7_HUMAN,tr|D6RIT2|D6RIT2_HUMAN,tr|D6R9T0|D6R9T0_HUMAN,tr|D6RIU0|D6RIU0_HUMAN,tr|D6RAM1|D6RAM1_HUMAN,tr|D6RBM0|D6RBM0_HUMAN,tr|G8JLB6|G8JLB6_HUMAN,tr|D6RF17|D6RF17_HUMAN,tr|D6RDL0|D6RDL0_HUMAN,tr|D6RDU3|D6RDU3_HUMAN,tr|E7EN40|E7EN40_HUMAN" 18 1503.6776 1.17 32212 16931 2 1503.677466 752.8461 Heterogeneous nuclear ribonucleoprotein H OS=Homo sapiens OX=9606 GN=HNRNPH1 PE=1 SV=4 4.37 2984.1 - 1.89E+06 - - - -0.1071 - 2.222 0.602 - 574.6 1 2 0 -0.0002 13 0 0 0 2.13E+08 1.82E+08 - - - 5.5365 0.9997 221125_WJC_METTL3_EV_vs_WT_F03.16932.16932.2 3.32E-05 20-Oct K.SSFNLGTIETK.S sp|P49790|NU153_HUMAN 1 1195.6085 0.81 32213 16932 2 1195.60946 598.8115 Nuclear pore complex protein Nup153 OS=Homo sapiens OX=9606 GN=NUP153 PE=1 SV=2 5.72 2984.1 - 1.87E+06 - - - 0.8297 - 1.654 0.494 - 234.2 1 2 0 0.001 11 0 0 0 9.57E+07 1.19E+08 - - - 4.0506 1 221125_WJC_METTL3_EV_vs_WT_F03.16933.16933.2 3.23E-09 24-Dec R.GLPWSC[160.03]SADEVQR[166.11].F "sp|P31943|HNRH1_HUMAN,tr|E7EQJ0|E7EQJ0_HUMAN,tr|D6R9D3|D6R9D3_HUMAN,tr|D6RIH9|D6RIH9_HUMAN,tr|D6RJ04|D6RJ04_HUMAN,tr|E5RGV0|E5RGV0_HUMAN,tr|D6RFM3|D6RFM3_HUMAN,tr|E9PCY7|E9PCY7_HUMAN,tr|D6RIT2|D6RIT2_HUMAN,tr|D6R9T0|D6R9T0_HUMAN,tr|D6RIU0|D6RIU0_HUMAN,tr|D6RAM1|D6RAM1_HUMAN,tr|D6RBM0|D6RBM0_HUMAN,tr|G8JLB6|G8JLB6_HUMAN,tr|D6RF17|D6RF17_HUMAN,tr|D6RDL0|D6RDL0_HUMAN,tr|D6RDU3|D6RDU3_HUMAN,tr|E7EN40|E7EN40_HUMAN" 18 1513.6859 1.17 32214 16933 2 1513.684268 757.8502 Heterogeneous nuclear ribonucleoprotein H OS=Homo sapiens OX=9606 GN=HNRNPH1 PE=1 SV=4 4.37 2984.2 - 1.60E+06 - - - -1.0762 - 2.543 0.693 - 408.4 1 2 0 -0.0016 13 0 0 0 2.13E+08 1.82E+08 - - - 6.5544 0.9999 221125_WJC_METTL3_EV_vs_WT_F03.16934.16934.2 0.00011 13/20 K.SSFNLGTIETK[136.11].S sp|P49790|NU153_HUMAN 1 1203.6227 0.74 32215 16934 2 1203.623526 602.8186 Nuclear pore complex protein Nup153 OS=Homo sapiens OX=9606 GN=NUP153 PE=1 SV=2 5.72 2984.3 - 1.49E+06 - - - 0.7128 - 2.236 0.518 - 447.9 1 2 0 0.0009 11 0 0 0 9.57E+07 1.30E+08 - - - 5.0436 1 221125_WJC_METTL3_EV_vs_WT_F03.16938.16938.2 1.17E-06 13/26 R.MVSEAGTGFC[160.03]FNTK.R sp|O75394|RM33_HUMAN 1 1547.6749 0.63 32219 16938 2 1547.672554 774.8447 "39S ribosomal protein L33, mitochondrial OS=Homo sapiens OX=9606 GN=MRPL33 PE=1 SV=1" 5.75 2984.8 - 896060 - - - -1.4835 - 2.565 0.624 - 369.2 1 2 0 -0.0023 14 0 0 0 1.03E+07 1.64E+07 - - - 6.0129 0.9999 221125_WJC_METTL3_EV_vs_WT_F03.16939.16939.2 0.00155 13/20 R.NQNEALLQAIK[136.11].A sp|O95801|TTC4_HUMAN 1 1248.6918 0.75 32220 16939 2 1248.690651 625.3532 Tetratricopeptide repeat protein 4 OS=Homo sapiens OX=9606 GN=TTC4 PE=1 SV=3 6 2984.9 - 895580 - - - -0.8809 - 2.632 0.426 - 723.7 1 2 0 -0.0011 11 0 0 0 1.24E+07 1.65E+07 - - - 4.8051 0.9999 221125_WJC_METTL3_EV_vs_WT_F03.16940.16940.2 0.000153 20-Dec R.NQNEALLQAIK.A sp|O95801|TTC4_HUMAN 1 1240.6776 0.75 32221 16940 2 1240.676704 621.3461 Tetratricopeptide repeat protein 4 OS=Homo sapiens OX=9606 GN=TTC4 PE=1 SV=3 6 2985.1 - 842273 - - - -0.6827 - 2.468 0.441 - 579.6 1 2 0 -0.0008 11 0 0 0 1.24E+07 1.65E+07 - - - 4.7419 0.9999 221125_WJC_METTL3_EV_vs_WT_F03.16943.16943.2 2.42E-06 20-Oct K.DQGLSIMVSGK.L "sp|Q00341|VIGLN_HUMAN,tr|C9JHZ8|C9JHZ8_HUMAN,tr|C9JZI8|C9JZI8_HUMAN,tr|A0A024R4E5|A0A024R4E5_HUMAN,tr|C9JIZ1|C9JIZ1_HUMAN,tr|H7C0A4|H7C0A4_HUMAN,tr|C9JES8|C9JES8_HUMAN,tr|C9J5E5|C9J5E5_HUMAN" 8 1133.5751 2.7 32224 16943 2 1133.575403 567.7948 Vigilin OS=Homo sapiens OX=9606 GN=HDLBP PE=1 SV=2 5.84 2985.5 - 500617 - - - 0.3035 - 2.003 0.519 - 341.7 1 2 0 0.0003 11 0 0 0 5.38E+06 1.99E+06 - - - 4.7534 1 221125_WJC_METTL3_EV_vs_WT_F03.16944.16944.2 8.41E-09 13/34 R.VAPEEHPVLLTEAPLNPK[136.11].A "sp|P63261|ACTG_HUMAN,sp|P60709|ACTB_HUMAN,tr|A0A804GS07|A0A804GS07_HUMAN,tr|I3L3I0|I3L3I0_HUMAN,tr|G5E9R0|G5E9R0_HUMAN,tr|E7EVS6|E7EVS6_HUMAN,tr|A0A6Q8PFE4|A0A6Q8PFE4_HUMAN,tr|J3KT65|J3KT65_HUMAN,tr|I3L3R2|I3L3R2_HUMAN,tr|K7EM38|K7EM38_HUMAN,tr|A0A6Q8PH58|A0A6Q8PH58_HUMAN,tr|I3L1U9|I3L1U9_HUMAN,tr|A0A2R8Y793|A0A2R8Y793_HUMAN,tr|I3L4N8|I3L4N8_HUMAN,tr|A0A2R8YGF8|A0A2R8YGF8_HUMAN" 15 1961.0713 1.14 32225 16944 2 1961.070081 981.5429 "Actin, cytoplasmic 2 OS=Homo sapiens OX=9606 GN=ACTG1 PE=1 SV=1" 4.75 2985.6 - 463814 - - - -0.6359 - 2.853 0.624 - 393.5 1 2 0 -0.0012 18 0 0 0 4.99E+06 4.36E+06 - - - 6.2269 0.9997 221125_WJC_METTL3_EV_vs_WT_F03.16946.16946.3 0.000118 15/44 R.YQILPLHSQIPR[166.11].E sp|Q08211|DHX9_HUMAN 1 1473.8332 1.16 32226 16946 3 1473.834439 492.285 ATP-dependent RNA helicase A OS=Homo sapiens OX=9606 GN=DHX9 PE=1 SV=4 8.75 2985.9 - 4.29E+06 - - - 0.8719 - 2.506 0.291 - 293.6 1 2 0 0.0013 12 0 0 0 2.18E+08 1.88E+08 - - - 4.3305 1 221125_WJC_METTL3_EV_vs_WT_F03.16949.16949.2 1.63E-08 20-Dec R.FVMEVEVDGQK[136.11].F "sp|Q12906|ILF3_HUMAN,sp|Q96SI9|STRBP_HUMAN" 2 1287.626 1.11 32228 16949 2 1287.626444 644.8203 Interleukin enhancer-binding factor 3 OS=Homo sapiens OX=9606 GN=ILF3 PE=1 SV=3 4.14 2986.1 - 1.01E+07 - - - 0.3145 - 2.32 0.633 - 448.7 1 2 0 0.0004 11 0 0 0 1.56E+08 1.41E+08 - - - 5.9928 1 221125_WJC_METTL3_EV_vs_WT_F03.16951.16951.2 3.41E-07 13/24 R.LAPDYDALDVANK.L "sp|P62750|RL23A_HUMAN,tr|K7EMA7|K7EMA7_HUMAN,tr|H7BY10|H7BY10_HUMAN,tr|K7ERT8|K7ERT8_HUMAN,tr|A8MUS3|A8MUS3_HUMAN,tr|K7EJV9|K7EJV9_HUMAN" 6 1403.6933 0.71 32230 16951 2 1403.691255 702.8539 60S ribosomal protein L23a OS=Homo sapiens OX=9606 GN=RPL23A PE=1 SV=1 3.93 2986.2 - 3.51E+06 - - - -1.4284 - 2.716 0.613 - 598.3 1 2 0 -0.002 13 0 0 0 2.83E+08 3.99E+08 - - - 6.1324 0.9995 221125_WJC_METTL3_EV_vs_WT_F03.16952.16952.2 0.0133 18-Sep K.ELGITALHIK[136.11].L "sp|P62263|RS14_HUMAN,tr|A0A2R8Y811|A0A2R8Y811_HUMAN,tr|E5RH77|E5RH77_HUMAN" 3 1101.6637 1.25 32231 16952 2 1101.663877 551.8391 40S ribosomal protein S14 OS=Homo sapiens OX=9606 GN=RPS14 PE=1 SV=3 6.85 2986.3 - 3.18E+06 - - - 0.1198 - 1.868 0.318 - 266.2 1 2 0 0.0001 10 0 0 0 4.91E+08 3.92E+08 - - - 3.1339 0.9996 221125_WJC_METTL3_EV_vs_WT_F03.16953.16953.2 0.0135 16-Nov R.ISLADIAQK[136.11].L sp|O43242|PSMD3_HUMAN 1 965.5637 0.47 32232 16953 2 965.562887 483.7891 26S proteasome non-ATPase regulatory subunit 3 OS=Homo sapiens OX=9606 GN=PSMD3 PE=1 SV=2 5.84 2986.3 - 2.98E+06 - - - -0.8379 - 2.133 0.274 - 259.3 1 2 0 -0.0008 9 0 0 0 2.17E+07 4.60E+07 - - - 3.2561 1 221125_WJC_METTL3_EV_vs_WT_F03.16954.16954.2 4.07E-10 17/28 K.NQVALNPQNTVFDAK[136.11].R "sp|P0DMV8|HS71A_HUMAN,sp|P0DMV9|HS71B_HUMAN,tr|A0A0G2JIW1|A0A0G2JIW1_HUMAN" 3 1665.8566 0.12 32233 16954 2 1665.854238 833.9356 Heat shock 70 kDa protein 1A OS=Homo sapiens OX=9606 GN=HSPA1A PE=1 SV=1 5.84 2986.4 - 2.19E+06 - - - -1.4083 - 3.364 0.659 - 711.3 1 2 0 -0.0023 15 0 0 0 4.38E+06 3.58E+07 - - - 6.8902 1 221125_WJC_METTL3_EV_vs_WT_F03.16959.16959.2 1.93E-10 14/26 R.MVSEAGTGFC[160.03]FNTK[136.11].R sp|O75394|RM33_HUMAN 1 1555.689 0.77 32238 16959 2 1555.68882 778.8518 "39S ribosomal protein L33, mitochondrial OS=Homo sapiens OX=9606 GN=MRPL33 PE=1 SV=1" 5.75 2987 - 1.13E+06 - - - -0.1478 - 2.665 0.664 - 491.3 1 2 0 -0.0002 14 0 0 0 1.01E+07 1.32E+07 - - - 6.405 1 221125_WJC_METTL3_EV_vs_WT_F03.16960.16960.2 5.31E-09 13/22 K.ANNYNEAVYLVR.F sp|Q09161|NCBP1_HUMAN 1 1424.7048 1.77 32239 16960 2 1424.703954 713.3597 Nuclear cap-binding protein subunit 1 OS=Homo sapiens OX=9606 GN=NCBP1 PE=1 SV=1 6.05 2987.1 - 1.13E+06 - - - -0.6135 - 2.999 0.607 - 942.9 1 2 0 -0.0009 12 0 0 0 1.46E+07 8.25E+06 - - - 6.4138 0.9998 221125_WJC_METTL3_EV_vs_WT_F03.16961.16961.2 7.14E-06 13/22 K.ANNYNEAVYLVR[166.11].F sp|Q09161|NCBP1_HUMAN 1 1434.7131 1.77 32240 16961 2 1434.710547 718.3638 Nuclear cap-binding protein subunit 1 OS=Homo sapiens OX=9606 GN=NCBP1 PE=1 SV=1 6.05 2987.2 - 995903 - - - -1.7781 - 3.165 0.461 - 967.8 1 2 0 -0.0026 12 0 0 0 1.46E+07 8.25E+06 - - - 5.4767 0.9996 221125_WJC_METTL3_EV_vs_WT_F03.16964.16964.3 0.0019 Sep-64 R.MPFPVNHGASSEDTLLK[136.11].D "sp|P09936|UCHL1_HUMAN,tr|D6R956|D6R956_HUMAN,tr|D6RE83|D6RE83_HUMAN" 3 1849.9124 0.97 32243 16964 3 1849.911998 617.6447 Ubiquitin carboxyl-terminal hydrolase isozyme L1 OS=Homo sapiens OX=9606 GN=UCHL1 PE=1 SV=2 5.3 2987.6 - 483966 - - - -0.2092 - 1.826 0.349 - 59.1 1 2 0 -0.0004 17 0 0 0 7.88E+06 8.13E+06 - - - 3.9521 0.9996 221125_WJC_METTL3_EV_vs_WT_F03.16968.16968.2 0.00124 18-Oct K.ELGITALHIK.L "sp|P62263|RS14_HUMAN,tr|A0A2R8Y811|A0A2R8Y811_HUMAN,tr|E5RH77|E5RH77_HUMAN" 3 1093.6495 1.25 32245 16968 2 1093.648729 547.832 40S ribosomal protein S14 OS=Homo sapiens OX=9606 GN=RPS14 PE=1 SV=3 6.85 2988.1 - 1.22E+07 - - - -0.7461 - 1.897 0.356 - 350.1 1 2 0 -0.0008 10 0 0 0 4.91E+08 3.92E+08 - - - 3.4574 0.9988 221125_WJC_METTL3_EV_vs_WT_F03.16969.16969.2 0.0201 16-Aug K.DLAGSIIGK.G "sp|P61978|HNRPK_HUMAN,tr|S4R359|S4R359_HUMAN" 2 872.4967 1.24 32246 16969 2 872.495998 437.2556 Heterogeneous nuclear ribonucleoprotein K OS=Homo sapiens OX=9606 GN=HNRNPK PE=1 SV=1 5.84 2988.1 - 4.85E+06 - - - -0.8424 - 1.443 0.298 - 154.9 1 2 0 -0.0007 9 0 0 0 7.52E+07 6.07E+07 - - - 2.3028 1 221125_WJC_METTL3_EV_vs_WT_F03.16970.16970.3 2.46E-08 19/44 R.YLR[166.11]PPNTSLFVR[166.11].N "sp|O75494|SRS10_HUMAN,tr|Q5JRI1|Q5JRI1_HUMAN,tr|Q6IQ42|Q6IQ42_HUMAN,tr|R4GMP8|R4GMP8_HUMAN" 4 1481.8258 2.4 32247 16970 3 1481.824741 494.9492 Serine\arginine-rich splicing factor 10 OS=Homo sapiens OX=9606 GN=SRSF10 PE=1 SV=1 10.84 2988.1 - 5.62E+06 - - - -0.6964 - 3.227 0.631 - 397 1 2 0 -0.001 12 0 0 0 2.75E+08 1.15E+08 - - - 8.8221 0.8705 221125_WJC_METTL3_EV_vs_WT_F03.16971.16971.2 0.0206 14-Sep L.GITALHIK.L "sp|P62263|RS14_HUMAN,tr|A0A2R8Y811|A0A2R8Y811_HUMAN,tr|E5RH77|E5RH77_HUMAN" 3 851.5229 1.26 32248 16971 2 851.521953 426.7687 40S ribosomal protein S14 OS=Homo sapiens OX=9606 GN=RPS14 PE=1 SV=3 8.76 2988.2 - 5.25E+06 - - - -1.098 - 1.475 0.215 - 192.2 1 1 0 -0.0009 8 0 0 0 1.89E+08 1.50E+08 - - - 1.8009 0.9998 221125_WJC_METTL3_EV_vs_WT_F03.16972.16972.3 0.000428 13/52 R.VLNDSLTPEIEADR.S sp|Q9UI36|DACH1_HUMAN 1 1570.7839 1.55 32249 16972 3 1570.784259 524.6019 Dachshund homolog 1 OS=Homo sapiens OX=9606 GN=DACH1 PE=1 SV=4 3.92 2988.3 - 1.98E+06 - - - 0.2502 - 2.457 0.347 - 313.3 1 2 0 0.0004 14 0 0 0 2.47E+07 1.60E+07 - - - 4.7976 0.8977 221125_WJC_METTL3_EV_vs_WT_F03.16974.16974.3 0.335 Dec-52 R.TLAEGFPGLEAASR[166.11].W sp|Q8N271|PROM2_HUMAN 1 1427.7284 0.1 32251 16974 3 1427.732346 476.9167 Prominin-2 OS=Homo sapiens OX=9606 GN=PROM2 PE=1 SV=1 4.53 2988.5 - 1.65E+06 - - - 2.754 - 1.623 0.125 - 77.5 2 2 0 0.0039 14 0 0 0 1.49E+06 1.54E+07 - - - 1.0802 0.9994 221125_WJC_METTL3_EV_vs_WT_F03.16975.16975.2 0.00374 16-Oct R.ISLADIAQK.L sp|O43242|PSMD3_HUMAN 1 957.5495 0.47 32252 16975 2 957.548395 479.782 26S proteasome non-ATPase regulatory subunit 3 OS=Homo sapiens OX=9606 GN=PSMD3 PE=1 SV=2 5.84 2988.6 - 1.52E+06 - - - -1.1498 - 2.017 0.282 - 193.1 1 2 0 -0.0011 9 0 0 0 2.17E+07 4.60E+07 - - - 3.1533 0.8665 221125_WJC_METTL3_EV_vs_WT_F03.16979.16979.2 0.025 14-Sep L.GITALHIK[136.11].L "sp|P62263|RS14_HUMAN,tr|A0A2R8Y811|A0A2R8Y811_HUMAN,tr|E5RH77|E5RH77_HUMAN" 3 859.5371 1.26 32254 16979 2 859.535772 430.7758 40S ribosomal protein S14 OS=Homo sapiens OX=9606 GN=RPS14 PE=1 SV=3 8.76 2989.1 - 7.54E+06 - - - -1.5311 - 1.511 0.227 - 213.6 1 1 0 -0.0013 8 0 0 0 1.89E+08 1.50E+08 - - - 1.9621 0.9975 221125_WJC_METTL3_EV_vs_WT_F03.16980.16980.3 0.186 Dec-48 K.ITYVPAEHLEEFK.L "sp|O75970|MPDZ_HUMAN,tr|H0YGQ3|H0YGQ3_HUMAN,tr|F5H1U9|F5H1U9_HUMAN" 3 1574.7981 2.71 32255 16980 3 1574.793638 525.94 Multiple PDZ domain protein OS=Homo sapiens OX=9606 GN=MPDZ PE=1 SV=2 4.75 2989.2 - 2.49E+06 - - - -2.808 - 2.121 0.262 - 167.2 1 2 0 -0.0044 13 0 0 0 2.99E+07 1.10E+07 - - - 3.4984 0.9998 221125_WJC_METTL3_EV_vs_WT_F03.16982.16982.2 0.00115 14/28 K.VAPSAVLGPNVSIGK[136.11].G "sp|Q96IJ6|GMPPA_HUMAN,tr|A0A0U1RRC2|A0A0U1RRC2_HUMAN,tr|A0A804HIS0|A0A804HIS0_HUMAN,tr|A0A087WUI8|A0A087WUI8_HUMAN" 4 1415.8228 1.01 32257 16982 2 1415.820547 708.9187 Mannose-1-phosphate guanyltransferase alpha OS=Homo sapiens OX=9606 GN=GMPPA PE=1 SV=1 8.72 2989.3 - 2.97E+06 - - - -1.5666 - 3.096 0.482 - 632.2 1 2 0 -0.0022 15 0 0 0 3.91E+07 3.86E+07 - - - 5.3788 0.9997 221125_WJC_METTL3_EV_vs_WT_F03.16983.16983.2 0.000144 22-Nov K.NVPQVVNVQELK[136.11].N "sp|P35658|NU214_HUMAN,tr|A0A0A0MSW3|A0A0A0MSW3_HUMAN,tr|H0YF36|H0YF36_HUMAN,tr|A0A494C1F2|A0A494C1F2_HUMAN" 4 1373.7758 1.94 32258 16983 2 1373.774206 687.8952 Nuclear pore complex protein Nup214 OS=Homo sapiens OX=9606 GN=NUP214 PE=1 SV=2 6 2989.3 - 2.26E+06 - - - -1.1712 - 1.896 0.415 - 304.7 1 2 0 -0.0016 12 0 0 0 2.18E+08 1.12E+08 - - - 3.789 0.9998 221125_WJC_METTL3_EV_vs_WT_F03.16985.16985.2 0.00031 20-Oct R.IYVGNLPTDVR.E "sp|Q13242|SRSF9_HUMAN,tr|H0YIB4|H0YIB4_HUMAN,tr|S4R3G0|S4R3G0_HUMAN" 3 1245.6717 2.61 32260 16985 2 1245.672318 623.8431 Serine\arginine-rich splicing factor 9 OS=Homo sapiens OX=9606 GN=SRSF9 PE=1 SV=1 5.84 2989.5 - 1.06E+06 - - - 0.4664 - 2.148 0.462 - 345.3 1 2 0 0.0006 11 0 0 0 1.88E+07 7.21E+06 - - - 4.5214 0.9992 221125_WJC_METTL3_EV_vs_WT_F03.16988.16988.3 0.0825 28-Jul K.FHNWFDDR[166.11].A "sp|P46977|STT3A_HUMAN,tr|A0A0C4DH80|A0A0C4DH80_HUMAN,tr|E9PN73|E9PN73_HUMAN,tr|E9PI32|E9PI32_HUMAN" 4 1145.4918 0.04 32263 16988 3 1145.491126 382.8379 Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit STT3A OS=Homo sapiens OX=9606 GN=STT3A PE=1 SV=2 5.21 2989.9 - 695099 - - - -0.5989 - 1.516 0.326 - 100.2 1 2 0 -0.0007 8 0 0 0 2.21E+05 6.14E+06 - - - 3.4748 0.9826 221125_WJC_METTL3_EV_vs_WT_F03.16990.16990.2 0.264 18-Sep R.NLSMPDLENR.L "sp|Q13425|SNTB2_HUMAN,tr|H0YCS0|H0YCS0_HUMAN,tr|H7BY41|H7BY41_HUMAN" 3 1187.5605 1.15 32265 16990 2 1187.557962 594.7875 Beta-2-syntrophin OS=Homo sapiens OX=9606 GN=SNTB2 PE=1 SV=1 4.37 2990.1 - 317509 - - - -2.1136 - 1.335 0.131 - 169.5 1 2 0 -0.0025 10 0 0 0 4.53E+06 3.94E+06 - - - 0.8143 1 221125_WJC_METTL3_EV_vs_WT_F03.16993.16993.2 6.90E-08 14/28 R.ILGADTSVDLEETGR.V "sp|P25705|ATPA_HUMAN,tr|K7EQH4|K7EQH4_HUMAN,tr|K7ERX7|K7ERX7_HUMAN,tr|K7EK77|K7EK77_HUMAN,tr|K7EJP1|K7EJP1_HUMAN,tr|K7ESA0|K7ESA0_HUMAN" 6 1574.7788 1.36 32266 16993 2 1574.777954 788.3967 "ATP synthase subunit alpha, mitochondrial OS=Homo sapiens OX=9606 GN=ATP5F1A PE=1 SV=1" 3.92 2990.5 - 2.48E+07 - - - -0.5252 - 3.083 0.675 - 622.7 1 2 0 -0.0008 15 0 0 0 3.90E+08 2.87E+08 - - - 6.7944 0.9999 221125_WJC_METTL3_EV_vs_WT_F03.16994.16994.3 0.00196 Dec-40 K.NFDLR[166.11]PGVIVR[166.11].D "sp|Q00266|METK1_HUMAN,sp|P31153|METK2_HUMAN" 2 1304.7468 1.13 32267 16994 3 1304.745654 435.9229 S-adenosylmethionine synthase isoform type-1 OS=Homo sapiens OX=9606 GN=MAT1A PE=1 SV=2 9.6 2990.6 - 4.21E+06 - - - -0.8745 - 2.157 0.414 - 236.1 1 2 0 -0.0011 11 0 0 0 6.75E+07 5.96E+07 - - - 5.3392 0.9934 221125_WJC_METTL3_EV_vs_WT_F03.16995.16995.2 0.206 18-Aug K.AISSDMYFGR[166.11].Q "sp|Q9NP61|ARFG3_HUMAN,tr|H0Y6A0|H0Y6A0_HUMAN" 2 1155.5258 0.94 32268 16995 2 1155.525793 578.7702 ADP-ribosylation factor GTPase-activating protein 3 OS=Homo sapiens OX=9606 GN=ARFGAP3 PE=1 SV=1 5.88 2990.7 - 1.66E+06 - - - -0.0182 - 1.117 0.21 - 147.9 1 2 0 0 10 0 0 0 2.76E+07 2.94E+07 - - - 0.9009 0.9887 221125_WJC_METTL3_EV_vs_WT_F03.16996.16996.2 0.397 18-Jul K.AISSDMYFGR.Q "sp|Q9NP61|ARFG3_HUMAN,tr|H0Y6A0|H0Y6A0_HUMAN" 2 1145.5175 0.94 32269 16996 2 1145.51912 573.766 ADP-ribosylation factor GTPase-activating protein 3 OS=Homo sapiens OX=9606 GN=ARFGAP3 PE=1 SV=1 5.88 2990.8 - 1.57E+06 - - - 1.3758 - 1.154 0.192 - 93.4 1 2 0 0.0016 10 0 0 0 2.76E+07 2.94E+07 - - - 0.8584 0.9997 221125_WJC_METTL3_EV_vs_WT_F03.16997.16997.3 0.000453 Nov-48 R.LAPDYDALDVANK[136.11].L "sp|P62750|RL23A_HUMAN,tr|K7EMA7|K7EMA7_HUMAN,tr|H7BY10|H7BY10_HUMAN,tr|K7ERT8|K7ERT8_HUMAN,tr|A8MUS3|A8MUS3_HUMAN,tr|K7EJV9|K7EJV9_HUMAN" 6 1411.7075 0.64 32270 16997 3 1411.705243 471.5764 60S ribosomal protein L23a OS=Homo sapiens OX=9606 GN=RPL23A PE=1 SV=1 3.93 2990.9 - 1.40E+06 - - - -1.5704 - 1.942 0.362 - 203.6 1 2 0 -0.0022 13 0 0 0 1.44E+07 2.23E+07 - - - 4.3749 0.9997 221125_WJC_METTL3_EV_vs_WT_F03.16998.16998.2 3.32E-05 24-Oct R.ITSPLMEPSSIEK[136.11].L sp|P28066|PSA5_HUMAN 1 1438.7469 0.87 32271 16998 2 1438.748628 720.3807 Proteasome subunit alpha type-5 OS=Homo sapiens OX=9606 GN=PSMA5 PE=1 SV=3 4.53 2991 - 625437 - - - 1.2136 - 2.131 0.432 - 307.5 1 2 0 0.0017 13 0 0 0 2.01E+07 2.30E+07 - - - 4.173 0.9998 221125_WJC_METTL3_EV_vs_WT_F03.17002.17002.2 5.97E-05 22-Nov K.NVPQVVNVQELK.N "sp|P35658|NU214_HUMAN,tr|A0A0A0MSW3|A0A0A0MSW3_HUMAN,tr|H0YF36|H0YF36_HUMAN,tr|A0A494C1F2|A0A494C1F2_HUMAN" 4 1365.7616 1.94 32273 17002 2 1365.76133 683.8881 Nuclear pore complex protein Nup214 OS=Homo sapiens OX=9606 GN=NUP214 PE=1 SV=2 6 2991.6 - 1.12E+07 - - - -0.2087 - 1.858 0.487 - 359.5 1 2 0 -0.0003 12 0 0 0 2.18E+08 1.12E+08 - - - 4.2679 0.9885 221125_WJC_METTL3_EV_vs_WT_F03.17003.17003.2 0.00231 16-Dec E.LGITALHIK.L "sp|P62263|RS14_HUMAN,tr|A0A2R8Y811|A0A2R8Y811_HUMAN,tr|E5RH77|E5RH77_HUMAN" 3 964.607 1.27 32274 17003 2 964.606657 483.3108 40S ribosomal protein S14 OS=Homo sapiens OX=9606 GN=RPS14 PE=1 SV=3 8.76 2991.6 - 2.97E+06 - - - -0.3058 - 2.124 0.393 - 242.8 1 1 0 -0.0003 9 0 0 0 3.40E+07 2.68E+07 - - - 4.1229 0.839 221125_WJC_METTL3_EV_vs_WT_F03.17006.17006.2 0.0435 18-Sep R.EQISLYPEVK[136.11].G sp|Q9P032|NDUF4_HUMAN 1 1212.6482 1.8 32277 17006 2 1213.655334 607.3314 NADH dehydrogenase [ubiquinone] 1 alpha subcomplex assembly factor 4 OS=Homo sapiens OX=9606 GN=NDUFAF4 PE=1 SV=1 4.53 2991.8 - 1.67E+06 - - - 830.5624 - 1.902 0.262 - 295 1 2 0 1.0072 10 0 0 0 1.49E+08 8.25E+07 - - - 2.4544 0.9993 221125_WJC_METTL3_EV_vs_WT_F03.17007.17007.2 1.42E-05 22-Nov R.EVDIGIPDATGR.L "sp|P55072|TERA_HUMAN,tr|A0A7P0Z4C6|A0A7P0Z4C6_HUMAN,tr|A0A7I2V2Y2|A0A7I2V2Y2_HUMAN,tr|A0A7P0T8Q5|A0A7P0T8Q5_HUMAN,tr|C9JUP7|C9JUP7_HUMAN,tr|A0A7P0TAW3|A0A7P0TAW3_HUMAN,tr|A0A7I2V540|A0A7I2V540_HUMAN,tr|A0A7P0T8A3|A0A7P0T8A3_HUMAN,tr|A0A7P0TAQ1|A0A7P0TAQ1_HUMAN,tr|A0A7P0TAY0|A0A7P0TAY0_HUMAN" 10 1241.6252 0.86 32278 17007 2 1241.621711 621.8199 Transitional endoplasmic reticulum ATPase OS=Homo sapiens OX=9606 GN=VCP PE=1 SV=4 4.03 2991.9 - 1.59E+06 - - - -2.7947 - 1.918 0.461 - 379 1 2 0 -0.0035 12 0 0 0 3.53E+07 4.11E+07 - - - 4.1585 0.9983 221125_WJC_METTL3_EV_vs_WT_F03.17008.17008.2 0.296 18-Nov R.SIDISATIPK.F "sp|Q15003|CND2_HUMAN,tr|C9J470|C9J470_HUMAN,tr|C9JZP1|C9JZP1_HUMAN,tr|E9PHA2|E9PHA2_HUMAN" 4 1043.5863 1.04 32279 17008 2 1043.585153 522.8004 Condensin complex subunit 2 OS=Homo sapiens OX=9606 GN=NCAPH PE=1 SV=3 5.55 2991.9 - 1.39E+06 - - - -1.0761 - 1.637 0.229 - 315.2 1 2 0 -0.0011 10 0 0 0 2.99E+07 2.87E+07 - - - 2.1078 0.9999 221125_WJC_METTL3_EV_vs_WT_F03.17009.17009.3 0.00652 15/56 K.LQMEAPHIIVGTPGR.V "sp|P60842|IF4A1_HUMAN,tr|J3KTB5|J3KTB5_HUMAN,tr|J3KT12|J3KT12_HUMAN,tr|J3QKZ9|J3QKZ9_HUMAN,tr|J3QS69|J3QS69_HUMAN,tr|J3QL43|J3QL43_HUMAN,tr|J3KS25|J3KS25_HUMAN,tr|J3KSZ0|J3KSZ0_HUMAN,tr|J3QLN6|J3QLN6_HUMAN,tr|J3QR64|J3QR64_HUMAN" 10 1617.8661 1.19 32280 17009 3 1617.86903 540.296 Eukaryotic initiation factor 4A-I OS=Homo sapiens OX=9606 GN=EIF4A1 PE=1 SV=1 6.75 2992.1 - 718818 - - - 1.8135 - 2.763 0.416 - 303.8 1 2 0 0.0029 15 0 0 0 1.63E+07 1.37E+07 - - - 5.8291 0.9968 221125_WJC_METTL3_EV_vs_WT_F03.17010.17010.2 0.00926 18-Nov R.NQITQLESLK[136.11].Q sp|Q53EZ4|CEP55_HUMAN 1 1180.6543 1.44 32281 17010 2 1180.659676 591.3344 Centrosomal protein of 55 kDa OS=Homo sapiens OX=9606 GN=CEP55 PE=1 SV=3 6 2992.2 - 395876 - - - 4.5517 - 1.948 0.411 - 412.5 1 2 0 0.0054 10 0 0 0 1.47E+07 1.02E+07 - - - 3.9362 0.9988 221125_WJC_METTL3_EV_vs_WT_F03.17011.17011.2 0.109 16-Jul R.GLFDEYGSK[136.11].K "sp|Q58FF3|ENPLL_HUMAN,sp|P14625|ENPL_HUMAN,tr|A0A7P0T917|A0A7P0T917_HUMAN,tr|A0A7P0T823|A0A7P0T823_HUMAN,tr|A0A7P0TAE1|A0A7P0TAE1_HUMAN,tr|H0YIV0|H0YIV0_HUMAN,tr|A0A7P0TAY2|A0A7P0TAY2_HUMAN,tr|A0A087WT78|A0A087WT78_HUMAN,tr|A0A7P0TBC2|A0A7P0TBC2_HUMAN,tr|A0A7P0TAT8|A0A7P0TAT8_HUMAN" 10 1022.48 0.92 32282 17011 2 1022.479656 512.2473 Putative endoplasmin-like protein OS=Homo sapiens OX=9606 GN=HSP90B2P PE=5 SV=1 4.37 2992.3 - 296929 - - - -0.3619 - 1.235 0.348 - 113.2 1 2 0 -0.0004 9 0 0 0 8.02E+06 8.70E+06 - - - 2.2219 0.9999 221125_WJC_METTL3_EV_vs_WT_F03.17014.17014.2 6.93E-05 26-Nov K.IFVGGLSPDTPEEK.L "sp|Q14103|HNRPD_HUMAN,tr|H0Y8G5|H0Y8G5_HUMAN,tr|D6RF44|D6RF44_HUMAN,tr|D6RAF8|D6RAF8_HUMAN,tr|H0YA96|H0YA96_HUMAN" 5 1487.7508 1.43 32283 17014 2 1487.74913 744.8827 Heterogeneous nuclear ribonucleoprotein D0 OS=Homo sapiens OX=9606 GN=HNRNPD PE=1 SV=1 4.14 2992.7 - 1.01E+07 - - - -1.1057 - 1.988 0.561 - 345.5 1 2 0 -0.0016 14 0 0 0 4.87E+08 3.40E+08 - - - 4.9083 0.9782 221125_WJC_METTL3_EV_vs_WT_F03.17015.17015.2 0.00447 16-Oct L.DTIEIITDR.Q "sp|P22626|ROA2_HUMAN,tr|A0A7I2YQN4|A0A7I2YQN4_HUMAN,tr|A0A7I2V4N0|A0A7I2V4N0_HUMAN,tr|A0A024RA28|A0A024RA28_HUMAN,tr|A0A7I2V4N1|A0A7I2V4N1_HUMAN,tr|A0A7I2V4I6|A0A7I2V4I6_HUMAN,tr|A0A087WUI2|A0A087WUI2_HUMAN,tr|A0A7I2V4S4|A0A7I2V4S4_HUMAN,tr|A0A7I2V323|A0A7I2V323_HUMAN,tr|A0A7I2V3P1|A0A7I2V3P1_HUMAN,tr|A0A7I2V3P7|A0A7I2V3P7_HUMAN" 11 1074.5557 1.04 32284 17015 2 1074.557025 538.2851 Heterogeneous nuclear ribonucleoproteins A2\B1 OS=Homo sapiens OX=9606 GN=HNRNPA2B1 PE=1 SV=2 4.03 2992.8 - 1.36E+06 - - - 1.2293 - 2.036 0.365 - 323.5 1 1 0 0.0013 9 0 0 0 1.94E+07 1.87E+07 - - - 3.7934 0.9999 221125_WJC_METTL3_EV_vs_WT_F03.17016.17016.3 8.03E-07 14/56 K.VLAGDKNFITAEELR.R "sp|O43707|ACTN4_HUMAN,tr|F5GXS2|F5GXS2_HUMAN,tr|H7C144|H7C144_HUMAN" 3 1674.8941 2.3 32285 17016 3 1674.895891 559.3053 Alpha-actinin-4 OS=Homo sapiens OX=9606 GN=ACTN4 PE=1 SV=2 4.68 2992.9 - 2.02E+06 - - - 1.0783 - 2.692 0.584 - 268.4 1 2 1 0.0018 15 0 0 0 3.50E+07 1.52E+07 - - - 7.6345 0.9995 221125_WJC_METTL3_EV_vs_WT_F03.17017.17017.2 0.000116 20-Oct K.IVEIPFNSTNK[136.11].Y sp|P05023|AT1A1_HUMAN 1 1268.6856 1.7 32286 17017 2 1268.686331 635.3501 Sodium\potassium-transporting ATPase subunit alpha-1 OS=Homo sapiens OX=9606 GN=ATP1A1 PE=1 SV=1 6 2993 - 1.44E+06 - - - 0.5738 - 2.042 0.29 - 308.7 1 2 0 0.0007 11 0 0 0 1.08E+08 6.34E+07 - - - 3.1141 0.9995 221125_WJC_METTL3_EV_vs_WT_F03.17019.17019.2 0.0269 24-Nov K.IAVEPVNPSELPK.M sp|Q15029|U5S1_HUMAN 1 1391.766 2.5 32288 17019 2 1391.765835 696.8903 116 kDa U5 small nuclear ribonucleoprotein component OS=Homo sapiens OX=9606 GN=EFTUD2 PE=1 SV=1 4.53 2993.3 - 703873 - - - -0.1408 - 2.254 0.243 - 283 1 2 0 -0.0002 13 0 0 0 2.76E+07 1.11E+07 - - - 2.9216 0.9998 221125_WJC_METTL3_EV_vs_WT_F03.17020.17020.2 4.70E-06 28-Nov K.TVLPTVPESPEEEVK.A "sp|O75152|ZC11A_HUMAN,tr|E9PBY7|E9PBY7_HUMAN,tr|A0A1W2PPR9|A0A1W2PPR9_HUMAN,tr|E9PQ61|E9PQ61_HUMAN" 4 1652.8509 1.14 32289 17020 2 1652.853037 827.4327 Zinc finger CCCH domain-containing protein 11A OS=Homo sapiens OX=9606 GN=ZC3H11A PE=1 SV=3 4.09 2993.4 - 511912 - - - 1.3032 - 2.092 0.542 - 278.5 1 2 0 0.0022 15 0 0 0 1.29E+07 1.13E+07 - - - 4.8582 0.9997 221125_WJC_METTL3_EV_vs_WT_F03.17021.17021.2 3.98E-06 28-Sep K.TVLPTVPESPEEEVK[136.11].A "sp|O75152|ZC11A_HUMAN,tr|E9PBY7|E9PBY7_HUMAN,tr|A0A1W2PPR9|A0A1W2PPR9_HUMAN,tr|E9PQ61|E9PQ61_HUMAN" 4 1660.8651 1.14 32290 17021 2 1660.868361 831.4398 Zinc finger CCCH domain-containing protein 11A OS=Homo sapiens OX=9606 GN=ZC3H11A PE=1 SV=3 4.09 2993.5 - 460962 - - - 1.9737 - 1.976 0.508 - 158.4 1 2 0 0.0033 15 0 0 0 1.29E+07 1.13E+07 - - - 4.4665 0.8162 221125_WJC_METTL3_EV_vs_WT_F03.17022.17022.3 2.51 Oct-40 R.K[136.11]LPLAGQVLLK[136.11].S "sp|Q9Y6M1|IF2B2_HUMAN,tr|F8W930|F8W930_HUMAN" 2 1194.8035 1.55 32291 17022 3 1194.802549 399.2751 Insulin-like growth factor 2 mRNA-binding protein 2 OS=Homo sapiens OX=9606 GN=IGF2BP2 PE=1 SV=2 10 2993.6 - 1.11E+06 - - - -0.7792 - 1.107 0.111 - 65.6 1 2 0 -0.0009 11 0 0 0 1.44E+07 9.29E+06 - - - 0.0661 0.9991 221125_WJC_METTL3_EV_vs_WT_F03.17024.17024.3 0.00327 Aug-36 K.VK[136.11]PLLLQLQR[166.11].Q "sp|Q14999|CUL7_HUMAN,tr|A0A669KB95|A0A669KB95_HUMAN,tr|A0A669KBH4|A0A669KBH4_HUMAN" 3 1224.8037 1.23 32293 17024 3 1224.803412 409.2752 Cullin-7 OS=Homo sapiens OX=9606 GN=CUL7 PE=1 SV=2 11 2993.9 - 338544 - - - -0.2335 - 1.724 0.294 - 63.1 1 2 0 -0.0003 10 0 0 0 4.78E+06 3.89E+06 - - - 3.4083 0.9999 221125_WJC_METTL3_EV_vs_WT_F03.17028.17028.3 0.00076 15/56 K.VLAGDK[136.11]NFITAEELR[166.11].R "sp|O43707|ACTN4_HUMAN,tr|F5GXS2|F5GXS2_HUMAN,tr|H7C144|H7C144_HUMAN" 3 1692.9166 2.25 32295 17028 3 1692.91703 565.3128 Alpha-actinin-4 OS=Homo sapiens OX=9606 GN=ACTN4 PE=1 SV=2 4.68 2994.4 - 1.97E+06 - - - 0.2806 - 2.753 0.476 - 304.9 1 2 1 0.0005 15 0 0 0 3.44E+07 1.53E+07 - - - 6.4893 1 221125_WJC_METTL3_EV_vs_WT_F03.17030.17030.2 3.85E-08 13/26 K.IFVGGLSPDTPEEK[136.11].L "sp|Q14103|HNRPD_HUMAN,tr|H0Y8G5|H0Y8G5_HUMAN,tr|D6RF44|D6RF44_HUMAN,tr|D6RAF8|D6RAF8_HUMAN,tr|H0YA96|H0YA96_HUMAN" 5 1495.765 1.45 32297 17030 2 1495.765403 748.8898 Heterogeneous nuclear ribonucleoprotein D0 OS=Homo sapiens OX=9606 GN=HNRNPD PE=1 SV=1 4.14 2994.5 - 1.26E+07 - - - 0.2861 - 2.545 0.599 - 462.4 1 2 0 0.0004 14 0 0 0 4.94E+08 3.40E+08 - - - 5.8092 1 221125_WJC_METTL3_EV_vs_WT_F03.17031.17031.2 6.21E-07 14/28 R.ILGADTSVDLEETGR[166.11].V "sp|P25705|ATPA_HUMAN,tr|K7EQH4|K7EQH4_HUMAN,tr|K7ERX7|K7ERX7_HUMAN,tr|K7EK77|K7EK77_HUMAN,tr|K7EJP1|K7EJP1_HUMAN,tr|K7ESA0|K7ESA0_HUMAN" 6 1584.7871 1.36 32298 17031 2 1584.786349 793.4008 "ATP synthase subunit alpha, mitochondrial OS=Homo sapiens OX=9606 GN=ATP5F1A PE=1 SV=1" 3.92 2994.6 - 9.10E+06 - - - -0.443 - 2.845 0.587 - 499.9 1 2 0 -0.0007 15 0 0 0 3.91E+08 2.87E+08 - - - 5.9469 0.9996 221125_WJC_METTL3_EV_vs_WT_F03.17032.17032.2 0.00352 18-Oct R.NQITQLESLK.Q sp|Q53EZ4|CEP55_HUMAN 1 1172.6401 1.46 32299 17032 2 1172.641242 587.3273 Centrosomal protein of 55 kDa OS=Homo sapiens OX=9606 GN=CEP55 PE=1 SV=3 6 2994.6 - 1.20E+06 - - - 0.9722 - 1.941 0.351 - 339.4 1 2 0 0.0011 10 0 0 0 1.49E+07 1.02E+07 - - - 3.4843 0.9986 221125_WJC_METTL3_EV_vs_WT_F03.17033.17033.3 0.127 Aug-44 R.IVLLDSSLEYK[136.11]K[136.11].G "sp|P49368|TCPG_HUMAN,tr|B4DUR8|B4DUR8_HUMAN,tr|Q5SZX6|Q5SZX6_HUMAN" 3 1422.8305 0.14 32300 17033 3 1422.830929 475.2841 T-complex protein 1 subunit gamma OS=Homo sapiens OX=9606 GN=CCT3 PE=1 SV=4 6.07 2994.7 - 1.01E+06 - - - 0.3142 - 1.651 0.28 - 85.4 1 2 0 0.0004 12 0 0 0 2.30E+06 1.64E+07 - - - 3.0514 0.9983 221125_WJC_METTL3_EV_vs_WT_F03.17038.17038.3 0.0861 Dec-48 R.LGLSAIVR[166.11]PSSIR[166.11].Q sp|Q96BW9|TAM41_HUMAN 1 1387.8414 0.71 32305 17038 3 1387.841775 463.6211 "Phosphatidate cytidylyltransferase, mitochondrial OS=Homo sapiens OX=9606 GN=TAMM41 PE=1 SV=2" 12 2995.3 - 450286 - - - 0.2529 - 1.945 0.232 - 225.7 1 2 0 0.0004 13 0 0 0 3.50E+06 4.94E+06 - - - 2.9302 0.9844 221125_WJC_METTL3_EV_vs_WT_F03.17041.17041.3 0.000472 Nov-40 K.K[136.11]ANPDLPILIR[166.11].E sp|O43678|NDUA2_HUMAN 1 1266.7779 2.63 32308 17041 3 1266.778574 423.2666 NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 2 OS=Homo sapiens OX=9606 GN=NDUFA2 PE=1 SV=3 8.75 2995.7 - 316533 - - - 0.5502 - 2.084 0.082 - 115.8 1 2 0 0.0007 11 0 0 0 1.31E+07 4.98E+06 - - - 1.54 1 221125_WJC_METTL3_EV_vs_WT_F03.17048.17048.3 2.65E-05 15/48 K.SIMTIVGHTDVVK.D sp|Q9GZL7|WDR12_HUMAN 1 1398.7541 0.52 32313 17048 3 1398.753062 467.2586 Ribosome biogenesis protein WDR12 OS=Homo sapiens OX=9606 GN=WDR12 PE=1 SV=2 6.46 2996.5 - 1.16E+06 - - - -0.7321 - 2.707 0.452 - 198.8 1 2 0 -0.001 13 0 0 0 1.37E+07 2.63E+07 - - - 6.2791 0.9831 221125_WJC_METTL3_EV_vs_WT_F03.17049.17049.3 0.000231 Dec-40 R.KLVILEGELER.A "sp|P67936|TPM4_HUMAN,sp|P07951|TPM2_HUMAN,tr|A7XZE4|A7XZE4_HUMAN,tr|A0A2R8Y5V9|A0A2R8Y5V9_HUMAN,tr|A0A5F9UN72|A0A5F9UN72_HUMAN,tr|A0A2R8YEU4|A0A2R8YEU4_HUMAN,tr|A0A2R8YGX3|A0A2R8YGX3_HUMAN,tr|K7ENT6|K7ENT6_HUMAN,tr|A0A2R8YH90|A0A2R8YH90_HUMAN,tr|Q5TCU3|Q5TCU3_HUMAN,tr|A0A2R8YE05|A0A2R8YE05_HUMAN,tr|U3KQK2|U3KQK2_HUMAN,tr|A0A2R8YHD2|A0A2R8YHD2_HUMAN" 13 1297.7606 1.63 32314 17049 3 1297.760258 433.5941 Tropomyosin alpha-4 chain OS=Homo sapiens OX=9606 GN=TPM4 PE=1 SV=3 4.79 2996.6 - 1.08E+06 - - - -0.2265 - 2.314 0.051 - 318.9 1 2 0 -0.0003 11 0 0 0 9.42E+06 5.80E+06 - - - 1.4919 1 221125_WJC_METTL3_EV_vs_WT_F03.17050.17050.3 3.01E-06 13/52 K.IFVGGLSPDTPEEK[136.11].L "sp|Q14103|HNRPD_HUMAN,tr|H0Y8G5|H0Y8G5_HUMAN,tr|D6RF44|D6RF44_HUMAN,tr|D6RAF8|D6RAF8_HUMAN,tr|H0YA96|H0YA96_HUMAN" 5 1495.765 1.81 32315 17050 3 1495.764481 499.5956 Heterogeneous nuclear ribonucleoprotein D0 OS=Homo sapiens OX=9606 GN=HNRNPD PE=1 SV=1 4.14 2996.8 - 1.04E+06 - - - -0.3303 - 2.584 0.443 - 227.5 1 2 0 -0.0005 14 0 0 0 1.68E+07 9.25E+06 - - - 6.0018 0.9998 221125_WJC_METTL3_EV_vs_WT_F03.17051.17051.2 1.45E-05 20-Dec K.QLDAAIAWQGK.L "sp|Q9BUK6|MSTO1_HUMAN,tr|A0A3B3IUD2|A0A3B3IUD2_HUMAN" 2 1199.6299 0.68 32316 17051 2 1199.629622 600.8222 Protein misato homolog 1 OS=Homo sapiens OX=9606 GN=MSTO1 PE=1 SV=1 5.84 2996.9 - 942708 - - - -0.2084 - 2.153 0.435 - 423.1 1 2 0 -0.0003 11 0 0 0 1.44E+07 2.11E+07 - - - 4.3284 0.9994 221125_WJC_METTL3_EV_vs_WT_F03.17052.17052.2 0.00547 22-Oct K.SVVSDLEADDVK[136.11].G sp|P11388|TOP2A_HUMAN 1 1283.6336 1.34 32317 17052 2 1283.63191 642.8241 DNA topoisomerase 2-alpha OS=Homo sapiens OX=9606 GN=TOP2A PE=1 SV=3 3.84 2997 - 865519 - - - -1.3376 - 1.919 0.321 - 270.2 1 2 0 -0.0017 12 0 0 0 1.58E+07 1.18E+07 - - - 3.1264 0.9994 221125_WJC_METTL3_EV_vs_WT_F03.17055.17055.3 0.00747 Sep-32 K.SEIHLFLQR.C sp|Q15477|SKIV2_HUMAN 1 1141.6244 1.15 32320 17055 3 1141.625556 381.5487 Helicase SKI2W OS=Homo sapiens OX=9606 GN=SKIV2L PE=1 SV=3 6.47 2997.3 - 445594 - - - 1.0187 - 1.768 0.319 - 123.5 1 2 0 0.0012 9 0 0 0 5.08E+06 4.43E+06 - - - 3.8136 0.9986 221125_WJC_METTL3_EV_vs_WT_F03.17056.17056.2 0.000262 20-Oct K.QEVMISDLEER[166.11].L sp|P35580|MYH10_HUMAN 1 1357.6423 0.51 32321 17056 2 1357.646843 679.8284 Myosin-10 OS=Homo sapiens OX=9606 GN=MYH10 PE=1 SV=3 4 2997.4 - 242739 - - - 3.3455 - 1.955 0.408 - 462.2 1 2 0 0.0045 11 0 0 0 2.20E+06 4.34E+06 - - - 3.8666 0.9998 221125_WJC_METTL3_EV_vs_WT_F03.17060.17060.2 0.00827 15/18 R.KIAFAITAIK.G "sp|P62269|RS18_HUMAN,tr|A0A0G2JQH2|A0A0G2JQH2_HUMAN,tr|Q5GGW2|Q5GGW2_HUMAN" 3 1074.6801 0.76 32323 17060 2 1074.680441 538.3473 40S ribosomal protein S18 OS=Homo sapiens OX=9606 GN=RPS18 PE=1 SV=3 10 2997.9 - 1.89E+06 - - - 0.3015 - 2.44 0.324 - 639.1 1 2 0 0.0003 10 0 0 0 1.53E+07 2.00E+07 - - - 3.9238 0.9999 221125_WJC_METTL3_EV_vs_WT_F03.17064.17064.3 0.000566 Dec-52 K.IFVGGLSPDTPEEK.L "sp|Q14103|HNRPD_HUMAN,tr|H0Y8G5|H0Y8G5_HUMAN,tr|D6RF44|D6RF44_HUMAN,tr|D6RAF8|D6RAF8_HUMAN,tr|H0YA96|H0YA96_HUMAN" 5 1487.7508 1.72 32327 17064 3 1487.751462 496.9242 Heterogeneous nuclear ribonucleoprotein D0 OS=Homo sapiens OX=9606 GN=HNRNPD PE=1 SV=1 4.14 2998.2 - 1.77E+06 - - - 0.4618 - 2.252 0.395 - 165.8 1 2 0 0.0007 14 0 0 0 1.59E+07 9.25E+06 - - - 5.1011 0.9998 221125_WJC_METTL3_EV_vs_WT_F03.17065.17065.2 0.000682 18-Nov K.FNASQLITQR[166.11].A "sp|Q99623|PHB2_HUMAN,tr|F5H3X6|F5H3X6_HUMAN,tr|A0A7I2V5F0|A0A7I2V5F0_HUMAN,tr|F5GWA7|F5GWA7_HUMAN,tr|J3KPX7|J3KPX7_HUMAN,tr|F5GY37|F5GY37_HUMAN" 6 1186.6334 1.27 32328 17065 2 1186.633104 594.324 Prohibitin-2 OS=Homo sapiens OX=9606 GN=PHB2 PE=1 SV=2 9.75 2998.3 - 1.58E+06 - - - -0.2419 - 2.246 0.386 - 386.2 1 2 0 -0.0003 10 0 0 0 1.10E+08 8.67E+07 - - - 4.1505 0.9997 221125_WJC_METTL3_EV_vs_WT_F03.17066.17066.2 0.00158 20-Nov R.SQLEESISQLR.H "sp|Q9BUR5|MIC26_HUMAN,tr|H7C1U8|H7C1U8_HUMAN,tr|G3V1B6|G3V1B6_HUMAN" 3 1288.6623 1.22 32329 17066 2 1288.664968 645.3384 MICOS complex subunit MIC26 OS=Homo sapiens OX=9606 GN=APOO PE=1 SV=1 4.53 2998.4 - 1.19E+06 - - - 2.075 - 2.335 0.439 - 493.3 1 2 0 0.0027 11 0 0 0 7.18E+06 5.88E+06 - - - 4.5767 0.9998 221125_WJC_METTL3_EV_vs_WT_F03.17067.17067.3 0.00015 13/40 K.KANPDLPILIR.E sp|O43678|NDUA2_HUMAN 1 1248.7554 2.67 32330 17067 3 1248.756603 417.2591 NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 2 OS=Homo sapiens OX=9606 GN=NDUFA2 PE=1 SV=3 8.75 2998.5 - 975243 - - - 0.9578 - 2.378 0.315 - 437.2 1 2 0 0.0012 11 0 0 0 1.24E+07 4.66E+06 - - - 4.5125 0.9998 221125_WJC_METTL3_EV_vs_WT_F03.17068.17068.2 1.50E-05 18-Nov K.FNASQLITQR.A "sp|Q99623|PHB2_HUMAN,tr|F5H3X6|F5H3X6_HUMAN,tr|A0A7I2V5F0|A0A7I2V5F0_HUMAN,tr|F5GWA7|F5GWA7_HUMAN,tr|J3KPX7|J3KPX7_HUMAN,tr|F5GY37|F5GY37_HUMAN" 6 1176.6251 1.27 32331 17068 2 1176.626694 589.3198 Prohibitin-2 OS=Homo sapiens OX=9606 GN=PHB2 PE=1 SV=2 9.75 2998.6 - 936718 - - - 1.3369 - 2.269 0.505 - 460 1 2 0 0.0016 10 0 0 0 1.10E+08 8.67E+07 - - - 5.0575 0.9996 221125_WJC_METTL3_EV_vs_WT_F03.17069.17069.2 7.54E-05 20-Nov R.SQLEESISQLR[166.11].H "sp|Q9BUR5|MIC26_HUMAN,tr|H7C1U8|H7C1U8_HUMAN,tr|G3V1B6|G3V1B6_HUMAN" 3 1298.6706 1.22 32332 17069 2 1298.673468 650.3426 MICOS complex subunit MIC26 OS=Homo sapiens OX=9606 GN=APOO PE=1 SV=1 4.53 2998.7 - 822314 - - - 2.2361 - 2.461 0.418 - 460.7 1 2 0 0.0029 11 0 0 0 7.18E+06 5.88E+06 - - - 4.5637 0.9995 221125_WJC_METTL3_EV_vs_WT_F03.17070.17070.2 2.03E-07 26-Nov R.VMNTGSQFVMEGVK.N "sp|Q8WVM8|SCFD1_HUMAN,tr|A0A7I2V4U2|A0A7I2V4U2_HUMAN,tr|A0A7I2V4B8|A0A7I2V4B8_HUMAN,tr|A0A7I2V5Z4|A0A7I2V5Z4_HUMAN,tr|B7Z5N7|B7Z5N7_HUMAN,tr|A0A7I2V5I2|A0A7I2V5I2_HUMAN,tr|A0A7I2V2U5|A0A7I2V2U5_HUMAN,tr|A0A7I2V448|A0A7I2V448_HUMAN,tr|A0A7I2V320|A0A7I2V320_HUMAN,tr|A0A7I2V3G4|A0A7I2V3G4_HUMAN,tr|A0A7I2V3B4|A0A7I2V3B4_HUMAN,tr|G3V2M8|G3V2M8_HUMAN,tr|A0A7I2V4R0|A0A7I2V4R0_HUMAN" 13 1525.7269 1.68 32333 17070 2 1525.721881 763.8707 Sec1 family domain-containing protein 1 OS=Homo sapiens OX=9606 GN=SCFD1 PE=1 SV=4 5.97 2998.8 - 624136 - - - -3.2797 - 2.496 0.576 - 340.4 1 2 0 -0.005 14 0 0 0 8.64E+06 5.13E+06 - - - 5.5891 0.9999 221125_WJC_METTL3_EV_vs_WT_F03.17071.17071.3 4.10E-05 Dec-36 K.LFHEVVQAFR[166.11].A sp|Q9Y3T9|NOC2L_HUMAN 1 1254.6749 0.81 32334 17071 3 1254.674632 419.2322 Nucleolar complex protein 2 homolog OS=Homo sapiens OX=9606 GN=NOC2L PE=1 SV=4 6.75 2999 - 620346 - - - -0.1833 - 2.323 0.397 - 270.2 1 2 0 -0.0002 10 0 0 0 6.68E+06 8.27E+06 - - - 5.4276 0.9801 221125_WJC_METTL3_EV_vs_WT_F03.17073.17073.2 7.70E-06 30-Sep K.IFVGNVSAAC[160.03]TSQELR[166.11].S "sp|Q96PK6|RBM14_HUMAN,tr|B8ZZ74|B8ZZ74_HUMAN,tr|F8WDX3|F8WDX3_HUMAN,tr|A0A0A0MSL8|A0A0A0MSL8_HUMAN,tr|A0A0A6YYI9|A0A0A6YYI9_HUMAN" 5 1760.8755 1.71 32336 17073 2 1760.86595 881.445 RNA-binding protein 14 OS=Homo sapiens OX=9606 GN=RBM14 PE=1 SV=2 5.99 2999.2 - 221093 - - - -5.4172 - 2.029 0.245 - 205.1 1 2 0 -0.0095 16 0 0 0 1.69E+07 9.87E+06 - - - 2.5871 0.9995 221125_WJC_METTL3_EV_vs_WT_F03.17075.17075.2 0.000183 16-Jul R.EYQDLLNVK.M "sp|P08670|VIME_HUMAN,sp|P14136|GFAP_HUMAN,sp|P17661|DESM_HUMAN,sp|Q16352|AINX_HUMAN,sp|P07197|NFM_HUMAN,sp|P12036|NFH_HUMAN,sp|P07196|NFL_HUMAN,tr|A0A1W2PR46|A0A1W2PR46_HUMAN,tr|A0A1X7SBR3|A0A1X7SBR3_HUMAN,tr|K7EJU1|K7EJU1_HUMAN,tr|A0A1X7SCE1|A0A1X7SCE1_HUMAN,tr|A0A1W2PRT3|A0A1W2PRT3_HUMAN,tr|B0YJC5|B0YJC5_HUMAN,tr|B0YJC4|B0YJC4_HUMAN,tr|E7ESP9|E7ESP9_HUMAN,tr|E7EMV2|E7EMV2_HUMAN" 16 1120.5764 1.99 32337 17075 2 1120.5779 561.2955 Vimentin OS=Homo sapiens OX=9606 GN=VIM PE=1 SV=4 4.37 2999.4 - 3.57E+07 - - - 1.3029 - 1.398 0.48 - 205.8 1 2 0 0.0015 9 0 0 0 2.51E+09 1.26E+09 - - - 3.5551 0.9997 221125_WJC_METTL3_EV_vs_WT_F03.17076.17076.2 0.000344 22-Dec K.SQVVAGTNYFIK.V "sp|P04080|CYTB_HUMAN,tr|A0A1W2PS52|A0A1W2PS52_HUMAN" 2 1325.698 0.5 32338 17076 2 1325.699116 663.8563 Cystatin-B OS=Homo sapiens OX=9606 GN=CSTB PE=1 SV=2 8.31 2999.5 - 5.06E+06 - - - 0.878 - 2.546 0.337 - 362.6 1 2 0 0.0012 12 0 0 0 3.42E+07 6.83E+07 - - - 3.9886 0.9998 221125_WJC_METTL3_EV_vs_WT_F03.17077.17077.2 0.000202 20-Sep K.WSEPNEEELIK[136.11].F "sp|P39748|FEN1_HUMAN,tr|I3L3E9|I3L3E9_HUMAN" 2 1380.6653 0.59 32339 17077 2 1380.666669 691.3399 Flap endonuclease 1 OS=Homo sapiens OX=9606 GN=FEN1 PE=1 SV=1 4.09 2999.5 - 3.95E+06 - - - 1.0198 - 1.78 0.487 - 169.4 1 2 0 0.0014 11 0 0 0 1.45E+07 2.44E+07 - - - 4.1974 0.9999 221125_WJC_METTL3_EV_vs_WT_F03.17078.17078.3 0.00955 Dec-44 K.IGILHENFQTLK[136.11].A "sp|Q9Y6G9|DC1L1_HUMAN,tr|E9PHI6|E9PHI6_HUMAN" 2 1419.7966 0.99 32340 17078 3 1419.796809 474.2728 Cytoplasmic dynein 1 light intermediate chain 1 OS=Homo sapiens OX=9606 GN=DYNC1LI1 PE=1 SV=3 6.75 2999.6 - 3.13E+06 - - - 0.1824 - 2.243 0.376 - 237.4 1 2 0 0.0003 12 0 0 0 1.39E+07 1.40E+07 - - - 4.9711 0.9999 221125_WJC_METTL3_EV_vs_WT_F03.17079.17079.2 0.00111 16/18 R.K[136.11]IAFAITAIK[136.11].G "sp|P62269|RS18_HUMAN,tr|A0A0G2JQH2|A0A0G2JQH2_HUMAN,tr|Q5GGW2|Q5GGW2_HUMAN" 3 1090.7085 0.76 32341 17079 2 1090.709203 546.3615 40S ribosomal protein S18 OS=Homo sapiens OX=9606 GN=RPS18 PE=1 SV=3 10 2999.7 - 2.72E+06 - - - 0.6289 - 2.843 0.448 - 758.3 1 2 0 0.0007 10 0 0 0 1.53E+07 2.00E+07 - - - 5.2662 0.9998 221125_WJC_METTL3_EV_vs_WT_F03.17084.17084.2 1.82E-07 22-Dec R.VPELNVQNGVLK[136.11].S "sp|O75533|SF3B1_HUMAN,tr|H7C341|H7C341_HUMAN" 2 1316.7544 0.98 32346 17084 2 1316.752821 659.3845 Splicing factor 3B subunit 1 OS=Homo sapiens OX=9606 GN=SF3B1 PE=1 SV=3 5.97 3000 - 1.29E+06 - - - -1.1619 - 2.339 0.47 - 384.5 1 2 0 -0.0015 12 0 0 0 9.59E+06 9.81E+06 - - - 4.7477 0.9998 221125_WJC_METTL3_EV_vs_WT_F03.17086.17086.2 0.000178 13/24 R.ADVDVQPYAFTTK[136.11].S sp|Q9BZE4|GTPB4_HUMAN 1 1461.7231 0.92 32348 17086 2 1461.725353 731.8688 GTP-binding protein 4 OS=Homo sapiens OX=9606 GN=GTPBP4 PE=1 SV=3 4.21 3000.2 - 988475 - - - 1.5345 - 2.462 0.476 - 585.8 1 2 0 0.0022 13 0 0 0 7.41E+06 8.08E+06 - - - 4.8684 1 221125_WJC_METTL3_EV_vs_WT_F03.17088.17088.2 1.14E-14 16/28 R.VGYYVNNEYTETELR.E sp|Q9Y294|ASF1A_HUMAN 1 1848.853 1.48 32350 17088 2 1848.855845 925.4338 Histone chaperone ASF1A OS=Homo sapiens OX=9606 GN=ASF1A PE=1 SV=1 4.25 3000.4 - 876590 - - - 1.5345 - 3.098 0.725 - 640.8 1 2 0 0.0028 15 0 0 0 6.13E+06 4.15E+06 - - - 7.175 0.9999 221125_WJC_METTL3_EV_vs_WT_F03.17089.17089.2 2.56E-07 26-Oct R.AAPC[160.03]DYGPAPAFYR[166.11].E sp|P17509|HXB6_HUMAN 1 1564.7008 2.2 32351 17089 2 1564.701296 783.3577 Homeobox protein Hox-B6 OS=Homo sapiens OX=9606 GN=HOXB6 PE=1 SV=4 5.87 3000.6 - 821764 - - - 0.3049 - 1.953 0.652 - 255.6 1 2 0 0.0005 14 0 0 0 2.37E+07 1.07E+07 - - - 5.5363 0.9925 221125_WJC_METTL3_EV_vs_WT_F03.17091.17091.2 2.27E-07 13/26 A.FSPSPGFSPYNVSK.T "sp|Q6PKH6|DR4L2_HUMAN,sp|Q9BTZ2|DHRS4_HUMAN,tr|A0A087WSZ6|A0A087WSZ6_HUMAN,tr|A0A087WXI8|A0A087WXI8_HUMAN,tr|H0YKN3|H0YKN3_HUMAN" 5 1512.7249 0.95 32353 17091 2 1512.726241 757.3697 Dehydrogenase\reductase SDR family member 4-like 2 OS=Homo sapiens OX=9606 GN=DHRS4L2 PE=2 SV=2 8.59 3000.8 - 761674 - - - 0.8898 - 2.486 0.53 - 500.5 1 1 0 0.0013 14 0 0 0 4.23E+06 4.43E+06 - - - 5.2405 0.9998 221125_WJC_METTL3_EV_vs_WT_F03.17092.17092.2 0.000252 22-Sep K.C[160.03]AVVDVPFGGAK.A "sp|P00367|DHE3_HUMAN,sp|P49448|DHE4_HUMAN,tr|A0A804HKE0|A0A804HKE0_HUMAN,tr|A0A804HJZ0|A0A804HJZ0_HUMAN,tr|A0A804HJD7|A0A804HJD7_HUMAN" 5 1218.6067 15.06 32354 17092 2 1218.606517 610.3106 "Glutamate dehydrogenase 1, mitochondrial OS=Homo sapiens OX=9606 GN=GLUD1 PE=1 SV=2" 5.83 3000.9 - 759874 - - - -0.1452 - 1.926 0.428 - 200.6 1 2 0 -0.0002 12 0 0 0 7.86E+06 5.22E+05 - - - 3.9267 1 221125_WJC_METTL3_EV_vs_WT_F03.17093.17093.2 1.02E-11 14/28 R.VGYYVNNEYTETELR[166.11].E sp|Q9Y294|ASF1A_HUMAN 1 1858.8613 1.48 32355 17093 2 1858.857882 930.4379 Histone chaperone ASF1A OS=Homo sapiens OX=9606 GN=ASF1A PE=1 SV=1 4.25 3001 - 680259 - - - -1.8269 - 2.801 0.708 - 447.9 1 2 0 -0.0034 15 0 0 0 6.13E+06 4.15E+06 - - - 6.8015 1 221125_WJC_METTL3_EV_vs_WT_F03.17094.17094.3 4.07E-07 25/52 R.IVATK[136.11]PLYVALAQR[166.11].K "sp|Q9H361|PABP3_HUMAN,sp|P11940|PABP1_HUMAN,tr|A0A7I2YQE4|A0A7I2YQE4_HUMAN,tr|A0A7I2V649|A0A7I2V649_HUMAN,tr|H0YB86|H0YB86_HUMAN,tr|H0YAR2|H0YAR2_HUMAN,tr|E7ERJ7|E7ERJ7_HUMAN,tr|A0A7I2YQ88|A0A7I2YQ88_HUMAN,tr|A0A087WTT1|A0A087WTT1_HUMAN,tr|A0A7I2YQ90|A0A7I2YQ90_HUMAN,tr|A0A7I2V4N4|A0A7I2V4N4_HUMAN,tr|E7EQV3|E7EQV3_HUMAN" 12 1559.9518 1.33 32356 17094 3 1559.952527 520.9912 Polyadenylate-binding protein 3 OS=Homo sapiens OX=9606 GN=PABPC3 PE=1 SV=2 9.99 3001.2 - 651618 - - - 0.4539 - 3.233 0.634 - 695.9 1 2 0 0.0007 14 0 0 0 1.03E+09 7.78E+08 - - - 8.7267 0.9997 221125_WJC_METTL3_EV_vs_WT_F03.17097.17097.2 0.00042 16-Aug R.VWQVTIGTR[166.11].- "sp|P63244|RACK1_HUMAN,tr|H0YAF8|H0YAF8_HUMAN,tr|D6RF23|D6RF23_HUMAN,tr|J3KPE3|J3KPE3_HUMAN,tr|D6RHJ5|D6RHJ5_HUMAN,tr|D6RHH4|D6RHH4_HUMAN,tr|D6RAC2|D6RAC2_HUMAN,tr|H0Y8R5|H0Y8R5_HUMAN" 8 1068.5955 0.89 32358 17097 2 1068.596359 535.3051 Receptor of activated protein C kinase 1 OS=Homo sapiens OX=9606 GN=RACK1 PE=1 SV=3 9.72 3001.6 - 737419 - - - 0.758 - 1.899 0.422 - 184.2 1 2 0 0.0008 9 0 0 0 2.96E+06 3.33E+06 - - - 4.013 0.9997 221125_WJC_METTL3_EV_vs_WT_F03.17098.17098.2 0.00827 14/24 K.IAVEPVNPSELPK[136.11].M sp|Q15029|U5S1_HUMAN 1 1399.7802 2.49 32359 17098 2 1399.781736 700.8974 116 kDa U5 small nuclear ribonucleoprotein component OS=Homo sapiens OX=9606 GN=EFTUD2 PE=1 SV=1 4.53 3001.6 - 2.24E+06 - - - 1.0752 - 2.444 0.331 - 598.6 1 2 0 0.0015 13 0 0 0 3.51E+07 1.41E+07 - - - 3.7788 1 221125_WJC_METTL3_EV_vs_WT_F03.17099.17099.3 1.36E-06 20/52 R.IVATKPLYVALAQR.K "sp|Q9H361|PABP3_HUMAN,sp|P11940|PABP1_HUMAN,tr|A0A7I2YQE4|A0A7I2YQE4_HUMAN,tr|A0A7I2V649|A0A7I2V649_HUMAN,tr|H0YB86|H0YB86_HUMAN,tr|H0YAR2|H0YAR2_HUMAN,tr|E7ERJ7|E7ERJ7_HUMAN,tr|A0A7I2YQ88|A0A7I2YQ88_HUMAN,tr|A0A087WTT1|A0A087WTT1_HUMAN,tr|A0A7I2YQ90|A0A7I2YQ90_HUMAN,tr|A0A7I2V4N4|A0A7I2V4N4_HUMAN,tr|E7EQV3|E7EQV3_HUMAN" 12 1541.9293 1.33 32360 17099 3 1541.930657 514.9837 Polyadenylate-binding protein 3 OS=Homo sapiens OX=9606 GN=PABPC3 PE=1 SV=2 9.99 3001.7 - 2.18E+06 - - - 0.8483 - 2.665 0.591 - 522.4 1 2 0 0.0013 14 0 0 0 1.03E+09 7.78E+08 - - - 7.7336 0.9121 221125_WJC_METTL3_EV_vs_WT_F03.17100.17100.2 1.1 16-Jul K.DIC[160.03]ELVINK.L sp|Q9P2G4|MAP10_HUMAN 1 1102.5692 2.85 32361 17100 2 1102.570869 552.2919 Microtubule-associated protein 10 OS=Homo sapiens OX=9606 GN=MAP10 PE=1 SV=2 4.37 3001.9 - 878740 - - - 1.472 - 1.145 0.011 - 149.5 1 2 0 0.0016 9 0 0 0 2.99E+07 1.05E+07 - - - -0.4865 1 221125_WJC_METTL3_EV_vs_WT_F03.17102.17102.2 5.54E-08 14/24 R.GSSGVGLTAAVLR[166.11].D sp|P33993|MCM7_HUMAN 1 1196.6753 0.17 32363 17102 2 1196.672151 599.3449 DNA replication licensing factor MCM7 OS=Homo sapiens OX=9606 GN=MCM7 PE=1 SV=4 9.75 3002.1 - 798057 - - - -2.5947 - 2.707 0.578 - 599.4 1 2 0 -0.0031 13 0 0 0 4.27E+06 2.50E+07 - - - 5.865 0.9996 221125_WJC_METTL3_EV_vs_WT_F03.17104.17104.3 0.000181 Dec-36 R.FSDFLGLHSK.L "sp|O60749|SNX2_HUMAN,tr|D6RC15|D6RC15_HUMAN" 2 1149.5819 1.1 32365 17104 3 1149.58067 384.2012 Sorting nexin-2 OS=Homo sapiens OX=9606 GN=SNX2 PE=1 SV=2 6.74 3002.3 - 751394 - - - -1.0343 - 2.042 0.306 - 104.4 1 2 0 -0.0012 10 0 0 0 2.15E+07 1.95E+07 - - - 4.0363 1 221125_WJC_METTL3_EV_vs_WT_F03.17105.17105.2 1.01E-07 13/28 K.LEVAMEEEGLADEEK.K "sp|Q9Y2H1|ST38L_HUMAN,tr|F5GY51|F5GY51_HUMAN,tr|I3L0D0|I3L0D0_HUMAN,tr|F5H7Z3|F5H7Z3_HUMAN" 4 1690.7607 5.11 32366 17105 2 1690.761633 846.3877 Serine\threonine-protein kinase 38-like OS=Homo sapiens OX=9606 GN=STK38L PE=1 SV=3 3.77 3002.5 - 677850 - - - 0.5234 - 2.746 0.63 - 416.8 1 2 0 0.0009 15 0 0 0 3.62E+06 7.08E+05 - - - 6.1774 0.9998 221125_WJC_METTL3_EV_vs_WT_F03.17106.17106.2 5.28E-05 14/26 K.EIDDSVLGQTGPYR.R "sp|O43615|TIM44_HUMAN,tr|M0QXU7|M0QXU7_HUMAN" 2 1548.742 1.23 32367 17106 2 1548.74513 775.3783 Mitochondrial import inner membrane translocase subunit TIM44 OS=Homo sapiens OX=9606 GN=TIMM44 PE=1 SV=2 4.03 3002.6 - 660605 - - - 2.0203 - 2.383 0.556 - 560.1 1 2 0 0.0031 14 0 0 0 1.39E+08 1.13E+08 - - - 5.3257 0.9995 221125_WJC_METTL3_EV_vs_WT_F03.17107.17107.2 0.0235 18-Aug K.TITWGITSC[160.03]K.A "sp|Q9Y4A5|TRRAP_HUMAN,tr|H0Y4W2|H0Y4W2_HUMAN,tr|F2Z2U4|F2Z2U4_HUMAN" 3 1165.5801 0.89 32368 17107 2 1165.580238 583.7973 Transformation\transcription domain-associated protein OS=Homo sapiens OX=9606 GN=TRRAP PE=1 SV=3 7.89 3002.7 - 570876 - - - 0.0798 - 1.635 0.357 - 158.2 1 2 0 0.0001 10 0 0 0 2.15E+06 2.41E+06 - - - 3.0501 0.9992 221125_WJC_METTL3_EV_vs_WT_F03.17108.17108.2 0.00302 16-Oct K.TLDEILQEK[136.11].K "sp|P21127|CD11B_HUMAN,sp|Q9UQ88|CD11A_HUMAN,tr|J3KS35|J3KS35_HUMAN,tr|E9PFJ2|E9PFJ2_HUMAN,tr|A0A0D9SER5|A0A0D9SER5_HUMAN,tr|Q5QPQ9|Q5QPQ9_HUMAN,tr|A0A087X1I0|A0A087X1I0_HUMAN,tr|E7ESP2|E7ESP2_HUMAN,tr|A0A0D9SEN2|A0A0D9SEN2_HUMAN,tr|A0A087WYI9|A0A087WYI9_HUMAN,tr|Q5QPR3|Q5QPR3_HUMAN,tr|A0A0D9SEI3|A0A0D9SEI3_HUMAN" 12 1095.5903 1.25 32369 17108 2 1095.587802 548.8024 Cyclin-dependent kinase 11B OS=Homo sapiens OX=9606 GN=CDK11B PE=1 SV=4 4.14 3002.9 - 549940 - - - -2.2846 - 1.934 0.346 - 286.7 1 2 0 -0.0025 9 0 0 0 3.19E+06 2.56E+06 - - - 3.504 0.9854 221125_WJC_METTL3_EV_vs_WT_F03.17109.17109.2 3.12E-05 26-Dec A.FSPSPGFSPYNVSK[136.11].T "sp|Q6PKH6|DR4L2_HUMAN,sp|Q9BTZ2|DHRS4_HUMAN,tr|A0A087WSZ6|A0A087WSZ6_HUMAN,tr|A0A087WXI8|A0A087WXI8_HUMAN,tr|H0YKN3|H0YKN3_HUMAN" 5 1520.7391 0.95 32370 17109 2 1520.739846 761.3768 Dehydrogenase\reductase SDR family member 4-like 2 OS=Homo sapiens OX=9606 GN=DHRS4L2 PE=2 SV=2 8.59 3003 - 524961 - - - 0.4938 - 2.001 0.424 - 445.2 1 1 0 0.0008 14 0 0 0 4.23E+06 4.43E+06 - - - 3.9131 0.9939 221125_WJC_METTL3_EV_vs_WT_F03.17111.17111.3 0.153 Aug-36 K.K[136.11]FDDENFILK[136.11].H "sp|Q9UNP9|PPIE_HUMAN,tr|E9PEQ6|E9PEQ6_HUMAN,tr|E9PKY5|E9PKY5_HUMAN" 3 1283.6733 2.01 32372 17111 3 1283.674832 428.8984 Peptidyl-prolyl cis-trans isomerase E OS=Homo sapiens OX=9606 GN=PPIE PE=1 SV=1 4.56 3003.2 - 413928 - - - 1.2301 - 1.501 0.226 - 107.6 1 2 0 0.0016 10 0 0 0 3.22E+06 1.60E+06 - - - 2.2453 0.9994 221125_WJC_METTL3_EV_vs_WT_F03.17113.17113.2 0.00162 22-Sep R.YQILPLHSQIPR[166.11].E sp|Q08211|DHX9_HUMAN 1 1473.8332 1.3 32374 17113 2 1473.834163 737.9239 ATP-dependent RNA helicase A OS=Homo sapiens OX=9606 GN=DHX9 PE=1 SV=4 8.75 3003.5 - 216096 - - - 0.6846 - 1.681 0.346 - 279.9 1 2 0 0.001 12 0 0 0 9.30E+06 7.17E+06 - - - 2.9628 0.999 221125_WJC_METTL3_EV_vs_WT_F03.17116.17116.2 0.0148 24-Sep R.ITSPLMEPSSIEK.L sp|P28066|PSA5_HUMAN 1 1430.7327 0.75 32376 17116 2 1430.734017 716.3736 Proteasome subunit alpha type-5 OS=Homo sapiens OX=9606 GN=PSMA5 PE=1 SV=3 4.53 3003.9 - 525246 - - - 0.9331 - 1.738 0.285 - 177.3 1 2 0 0.0013 13 0 0 0 1.65E+07 2.18E+07 - - - 2.5642 1 221125_WJC_METTL3_EV_vs_WT_F03.17117.17117.3 1.19E-08 16/48 R.LVHPGVAEVVFVK.K "sp|Q9BY77|PDIP3_HUMAN,tr|F6VRR5|F6VRR5_HUMAN" 2 1392.8129 1.47 32377 17117 3 1392.813052 465.2783 Polymerase delta-interacting protein 3 OS=Homo sapiens OX=9606 GN=POLDIP3 PE=1 SV=2 6.75 3003.9 - 5.98E+06 - - - 0.0933 - 3.058 0.62 - 440.9 1 2 0 0.0001 13 0 0 0 1.13E+08 7.69E+07 - - - 8.4829 0.9931 221125_WJC_METTL3_EV_vs_WT_F03.17118.17118.2 0.000546 20-Nov H.LQLWDTAGQER.F "sp|P51159|RB27A_HUMAN,sp|Q9H082|RB33B_HUMAN,sp|P20336|RAB3A_HUMAN,sp|Q8IZ41|RASEF_HUMAN,sp|P20337|RAB3B_HUMAN,sp|Q96E17|RAB3C_HUMAN,sp|P61006|RAB8A_HUMAN,sp|P61026|RAB10_HUMAN,sp|Q15286|RAB35_HUMAN,sp|O00194|RB27B_HUMAN,sp|Q14964|RB39A_HUMAN,sp|Q9H0U4|RAB1B_HUMAN,sp|P61018|RAB4B_HUMAN,sp|P59190|RAB15_HUMAN,sp|Q9BZG1|RAB34_HUMAN,sp|Q9NP90|RAB9B_HUMAN,sp|Q9BSW2|EFC4B_HUMAN,sp|P20338|RAB4A_HUMAN,sp|Q15771|RAB30_HUMAN,sp|P62820|RAB1A_HUMAN,sp|Q5JT25|RAB41_HUMAN,sp|Q86YS6|RAB43_HUMAN,sp|Q96DA2|RB39B_HUMAN,sp|P20340|RAB6A_HUMAN,sp|Q96AX2|RAB37_HUMAN,sp|Q7Z6P3|RAB44_HUMAN,sp|Q9NRW1|RAB6B_HUMAN,sp|O95716|RAB3D_HUMAN,sp|Q6IQ22|RAB12_HUMAN,sp|Q92930|RAB8B_HUMAN,sp|Q92928|RAB1C_HUMAN,sp|P61106|RAB14_HUMAN,tr|A8MZI4|A8MZI4_HUMAN,tr|A0A494C0Z5|A0A494C0Z5_HUMAN,tr|H3BVH7|H3BVH7_HUMAN,tr|E9PJQ5|E9PJQ5_HUMAN,tr|H0YMN7|H0YMN7_HUMAN,tr|C9JBG0|C9JBG0_HUMAN,tr|A8MTC6|A8MTC6_HUMAN,tr|B7Z3L0|B7Z3L0_HUMAN,tr|E9PS06|E9PS06_HUMAN,tr|A0A2R8Y7G7|A0A2R8Y7G7_HUMAN,tr|A8MSP2|A8MSP2_HUMAN,tr|E9PNB9|E9PNB9_HUMAN,tr|E9PLM3|E9PLM3_HUMAN,tr|H0YNE9|H0YNE9_HUMAN,tr|E9PI18|E9PI18_HUMAN,tr|G3V196|G3V196_HUMAN,tr|X6RFL8|X6RFL8_HUMAN,tr|Q6PIK3|Q6PIK3_HUMAN,tr|A0A3B3ITT1|A0A3B3ITT1_HUMAN,tr|Q96PJ7|Q96PJ7_HUMAN,tr|C9JB90|C9JB90_HUMAN,tr|J3KR73|J3KR73_HUMAN,tr|A0A2R8YFB8|A0A2R8YFB8_HUMAN,tr|H3BUD9|H3BUD9_HUMAN,tr|J3QLC6|J3QLC6_HUMAN,tr|M0R257|M0R257_HUMAN,tr|J3QSF4|J3QSF4_HUMAN,tr|E7ES60|E7ES60_HUMAN,tr|H0YDK7|H0YDK7_HUMAN,tr|C9JFM7|C9JFM7_HUMAN,tr|H3BS49|H3BS49_HUMAN,tr|M0R0X1|M0R0X1_HUMAN,tr|C9JY26|C9JY26_HUMAN,tr|K7ES41|K7ES41_HUMAN,tr|H3BN55|H3BN55_HUMAN,tr|H7C0Y7|H7C0Y7_HUMAN,tr|C9JU14|C9JU14_HUMAN,tr|E9PRF7|E9PRF7_HUMAN,tr|G3V562|G3V562_HUMAN,tr|F5H157|F5H157_HUMAN,tr|E9PMJ1|E9PMJ1_HUMAN,tr|K7EIF2|K7EIF2_HUMAN" 74 1315.6521 1.16 32378 17118 2 1315.651514 658.8333 Ras-related protein Rab-27A OS=Homo sapiens OX=9606 GN=RAB27A PE=1 SV=3 4.37 3003.9 - 4.97E+06 - - - -0.418 - 2.168 0.519 - 430.1 1 1 0 -0.0006 11 0 0 0 4.17E+08 3.60E+08 - - - 4.9675 1 221125_WJC_METTL3_EV_vs_WT_F03.17120.17120.3 0.000387 13/52 K.NPEVGLK[136.11]PVWYSPK[136.11].V "sp|P07814|SYEP_HUMAN,tr|V9GYZ6|V9GYZ6_HUMAN" 2 1628.8897 1.22 32380 17120 3 1628.890414 543.9705 Bifunctional glutamate\proline--tRNA ligase OS=Homo sapiens OX=9606 GN=EPRS1 PE=1 SV=5 8.5 3004.1 - 2.29E+06 - - - 0.4205 - 2.547 0.462 - 195.3 1 2 0 0.0007 14 0 0 0 1.88E+07 1.53E+07 - - - 6.1752 0.9999 221125_WJC_METTL3_EV_vs_WT_F03.17121.17121.3 0.000247 Nov-36 R.FSDFLGLHSK[136.11].L "sp|O60749|SNX2_HUMAN,tr|D6RC15|D6RC15_HUMAN" 2 1157.5961 1.11 32381 17121 3 1157.595061 386.8726 Sorting nexin-2 OS=Homo sapiens OX=9606 GN=SNX2 PE=1 SV=2 6.74 3004.1 - 2.26E+06 - - - -0.8621 - 1.779 0.459 - 87 1 2 0 -0.001 10 0 0 0 2.22E+07 1.99E+07 - - - 5.3394 1 221125_WJC_METTL3_EV_vs_WT_F03.17122.17122.3 6.65E-09 15/60 K.VFSDEVQQQAQLSTIR.S "sp|Q9Y262|EIF3L_HUMAN,tr|B0QY89|B0QY89_HUMAN,tr|B0QY90|B0QY90_HUMAN" 3 1847.9377 1.23 32382 17122 3 1847.936688 616.9865 Eukaryotic translation initiation factor 3 subunit L OS=Homo sapiens OX=9606 GN=EIF3L PE=1 SV=1 4.37 3004.2 - 1.92E+06 - - - -0.5698 - 3.072 0.542 - 324.2 1 2 0 -0.0011 16 0 0 0 8.96E+06 7.31E+06 - - - 7.4622 0.9989 221125_WJC_METTL3_EV_vs_WT_F03.17123.17123.2 3.14E-05 22-Dec R.STGEAFVQFASK[136.11].E sp|P31942|HNRH3_HUMAN 1 1278.6336 2.01 32383 17123 2 1278.638569 640.3241 Heterogeneous nuclear ribonucleoprotein H3 OS=Homo sapiens OX=9606 GN=HNRNPH3 PE=1 SV=2 5.72 3004.3 - 1.67E+06 - - - 3.912 - 2.383 0.471 - 735.8 1 2 0 0.005 12 0 0 0 1.90E+08 9.46E+07 - - - 4.803 1 221125_WJC_METTL3_EV_vs_WT_F03.17124.17124.3 1.06E-05 14/52 K.NPEVGLKPVWYSPK.V "sp|P07814|SYEP_HUMAN,tr|V9GYZ6|V9GYZ6_HUMAN" 2 1612.8613 1.04 32384 17124 3 1612.864542 538.6277 Bifunctional glutamate\proline--tRNA ligase OS=Homo sapiens OX=9606 GN=EPRS1 PE=1 SV=5 8.5 3004.3 - 1.47E+06 - - - 1.9921 - 2.942 0.485 - 203.8 1 2 0 0.0032 14 0 0 0 1.95E+07 1.88E+07 - - - 6.8141 1 221125_WJC_METTL3_EV_vs_WT_F03.17126.17126.3 0.000922 17/52 R.LLDSVPPTAISHFK[136.11].Q sp|Q9NR30|DDX21_HUMAN 1 1531.849 0.94 32386 17126 3 1531.848395 511.6236 Nucleolar RNA helicase 2 OS=Homo sapiens OX=9606 GN=DDX21 PE=1 SV=5 6.74 3004.5 - 1.25E+06 - - - -0.3819 - 3.089 0.418 - 408.3 1 2 0 -0.0006 14 0 0 0 3.10E+07 3.31E+07 - - - 6.1974 1 221125_WJC_METTL3_EV_vs_WT_F03.17127.17127.2 9.03E-12 17/34 K.TVAGGAWTYNTTSAVTVK[136.11].S "sp|P61513|RL37A_HUMAN,tr|C9J4Z3|C9J4Z3_HUMAN" 2 1833.9352 0.93 32387 17127 2 1833.935369 917.9749 60S ribosomal protein L37a OS=Homo sapiens OX=9606 GN=RPL37A PE=1 SV=2 8.26 3004.6 - 893801 - - - 0.0769 - 3.679 0.694 - 711.9 1 2 0 0.0001 18 0 0 0 1.62E+08 1.74E+08 - - - 7.3694 1 221125_WJC_METTL3_EV_vs_WT_F03.17128.17128.2 2.61E-07 15/26 R.IVATKPLYVALAQR.K "sp|Q9H361|PABP3_HUMAN,sp|P11940|PABP1_HUMAN,tr|A0A7I2YQE4|A0A7I2YQE4_HUMAN,tr|A0A7I2V649|A0A7I2V649_HUMAN,tr|H0YB86|H0YB86_HUMAN,tr|H0YAR2|H0YAR2_HUMAN,tr|E7ERJ7|E7ERJ7_HUMAN,tr|A0A7I2YQ88|A0A7I2YQ88_HUMAN,tr|A0A087WTT1|A0A087WTT1_HUMAN,tr|A0A7I2YQ90|A0A7I2YQ90_HUMAN,tr|A0A7I2V4N4|A0A7I2V4N4_HUMAN,tr|E7EQV3|E7EQV3_HUMAN" 12 1541.9293 1.43 32388 17128 2 1541.931442 771.972 Polyadenylate-binding protein 3 OS=Homo sapiens OX=9606 GN=PABPC3 PE=1 SV=2 9.99 3004.8 - 866356 - - - 1.3574 - 2.881 0.593 - 470.2 1 2 0 0.0021 14 0 0 0 1.04E+08 7.32E+07 - - - 6.0756 0.9998 221125_WJC_METTL3_EV_vs_WT_F03.17129.17129.2 8.42E-05 15/24 K.IGQLEEQLEQEAK[136.11].E sp|P35580|MYH10_HUMAN 1 1521.7766 0.9 32389 17129 2 1521.779407 761.8956 Myosin-10 OS=Homo sapiens OX=9606 GN=MYH10 PE=1 SV=3 4.09 3004.9 - 832162 - - - 1.8432 - 3.027 0.478 - 768.1 1 2 0 0.0028 13 0 0 0 6.09E+07 6.74E+07 - - - 5.4132 1 221125_WJC_METTL3_EV_vs_WT_F03.17130.17130.2 5.26E-13 21/34 K.TVAGGAWTYNTTSAVTVK.S "sp|P61513|RL37A_HUMAN,tr|C9J4Z3|C9J4Z3_HUMAN" 2 1825.921 0.93 32390 17130 2 1825.918812 913.9678 60S ribosomal protein L37a OS=Homo sapiens OX=9606 GN=RPL37A PE=1 SV=2 8.26 3005.1 - 706093 - - - -1.2136 - 3.967 0.692 - 1229.3 1 2 0 -0.0022 18 0 0 0 1.70E+08 1.83E+08 - - - 7.5393 0.9996 221125_WJC_METTL3_EV_vs_WT_F03.17131.17131.3 0.00105 Oct-36 K.KFDDENFILK.H "sp|Q9UNP9|PPIE_HUMAN,tr|E9PEQ6|E9PEQ6_HUMAN,tr|E9PKY5|E9PKY5_HUMAN" 3 1267.6449 2.01 32391 17131 3 1267.645813 423.5556 Peptidyl-prolyl cis-trans isomerase E OS=Homo sapiens OX=9606 GN=PPIE PE=1 SV=1 4.56 3005.2 - 619127 - - - 0.7573 - 1.825 0.337 - 179 1 2 0 0.001 10 0 0 0 2.88E+06 1.44E+06 - - - 4.0538 0.9999 221125_WJC_METTL3_EV_vs_WT_F03.17132.17132.3 0.000507 14/36 K.LDPELHLDIK[136.11].V "sp|Q12905|ILF2_HUMAN,tr|B4DY09|B4DY09_HUMAN" 2 1199.6641 1.41 32392 17132 3 1199.662834 400.8953 Interleukin enhancer-binding factor 2 OS=Homo sapiens OX=9606 GN=ILF2 PE=1 SV=2 4.54 3005.3 - 604513 - - - -1.0878 - 2.421 0.397 - 199.4 1 2 0 -0.0013 10 0 0 0 2.30E+07 1.63E+07 - - - 5.548 0.9994 221125_WJC_METTL3_EV_vs_WT_F03.17133.17133.2 0.000159 18-Oct R.FSDFLGLHSK.L "sp|O60749|SNX2_HUMAN,tr|D6RC15|D6RC15_HUMAN" 2 1149.5819 0.85 32393 17133 2 1149.578184 575.7982 Sorting nexin-2 OS=Homo sapiens OX=9606 GN=SNX2 PE=1 SV=2 6.74 3005.4 - 557067 - - - -3.1968 - 2.166 0.494 - 247.3 1 2 0 -0.0037 10 0 0 0 4.04E+06 4.77E+06 - - - 4.8459 0.9998 221125_WJC_METTL3_EV_vs_WT_F03.17135.17135.3 0.00775 13/44 R.YQILPLHSQIPR.E sp|Q08211|DHX9_HUMAN 1 1463.8249 1.01 32394 17135 3 1463.825111 488.9489 ATP-dependent RNA helicase A OS=Homo sapiens OX=9606 GN=DHX9 PE=1 SV=4 8.75 3005.7 - 3.07E+06 - - - 0.1551 - 2.085 0.353 - 196.2 1 2 0 0.0002 12 0 0 0 2.18E+07 2.16E+07 - - - 4.5122 0.9645 221125_WJC_METTL3_EV_vs_WT_F03.17137.17137.2 0.000593 20-Nov H.LQLWDTAGQER[166.11].F "sp|P51159|RB27A_HUMAN,sp|Q9H082|RB33B_HUMAN,sp|P20336|RAB3A_HUMAN,sp|Q8IZ41|RASEF_HUMAN,sp|P20337|RAB3B_HUMAN,sp|Q96E17|RAB3C_HUMAN,sp|P61006|RAB8A_HUMAN,sp|P61026|RAB10_HUMAN,sp|Q15286|RAB35_HUMAN,sp|O00194|RB27B_HUMAN,sp|Q14964|RB39A_HUMAN,sp|Q9H0U4|RAB1B_HUMAN,sp|P61018|RAB4B_HUMAN,sp|P59190|RAB15_HUMAN,sp|Q9BZG1|RAB34_HUMAN,sp|Q9NP90|RAB9B_HUMAN,sp|Q9BSW2|EFC4B_HUMAN,sp|P20338|RAB4A_HUMAN,sp|Q15771|RAB30_HUMAN,sp|P62820|RAB1A_HUMAN,sp|Q5JT25|RAB41_HUMAN,sp|Q86YS6|RAB43_HUMAN,sp|Q96DA2|RB39B_HUMAN,sp|P20340|RAB6A_HUMAN,sp|Q96AX2|RAB37_HUMAN,sp|Q7Z6P3|RAB44_HUMAN,sp|Q9NRW1|RAB6B_HUMAN,sp|O95716|RAB3D_HUMAN,sp|Q6IQ22|RAB12_HUMAN,sp|Q92930|RAB8B_HUMAN,sp|Q92928|RAB1C_HUMAN,sp|P61106|RAB14_HUMAN,tr|A8MZI4|A8MZI4_HUMAN,tr|A0A494C0Z5|A0A494C0Z5_HUMAN,tr|H3BVH7|H3BVH7_HUMAN,tr|E9PJQ5|E9PJQ5_HUMAN,tr|H0YMN7|H0YMN7_HUMAN,tr|C9JBG0|C9JBG0_HUMAN,tr|A8MTC6|A8MTC6_HUMAN,tr|B7Z3L0|B7Z3L0_HUMAN,tr|E9PS06|E9PS06_HUMAN,tr|A0A2R8Y7G7|A0A2R8Y7G7_HUMAN,tr|A8MSP2|A8MSP2_HUMAN,tr|E9PNB9|E9PNB9_HUMAN,tr|E9PLM3|E9PLM3_HUMAN,tr|H0YNE9|H0YNE9_HUMAN,tr|E9PI18|E9PI18_HUMAN,tr|G3V196|G3V196_HUMAN,tr|X6RFL8|X6RFL8_HUMAN,tr|Q6PIK3|Q6PIK3_HUMAN,tr|A0A3B3ITT1|A0A3B3ITT1_HUMAN,tr|Q96PJ7|Q96PJ7_HUMAN,tr|C9JB90|C9JB90_HUMAN,tr|J3KR73|J3KR73_HUMAN,tr|A0A2R8YFB8|A0A2R8YFB8_HUMAN,tr|H3BUD9|H3BUD9_HUMAN,tr|J3QLC6|J3QLC6_HUMAN,tr|M0R257|M0R257_HUMAN,tr|J3QSF4|J3QSF4_HUMAN,tr|E7ES60|E7ES60_HUMAN,tr|H0YDK7|H0YDK7_HUMAN,tr|C9JFM7|C9JFM7_HUMAN,tr|H3BS49|H3BS49_HUMAN,tr|M0R0X1|M0R0X1_HUMAN,tr|C9JY26|C9JY26_HUMAN,tr|K7ES41|K7ES41_HUMAN,tr|H3BN55|H3BN55_HUMAN,tr|H7C0Y7|H7C0Y7_HUMAN,tr|C9JU14|C9JU14_HUMAN,tr|E9PRF7|E9PRF7_HUMAN,tr|G3V562|G3V562_HUMAN,tr|F5H157|F5H157_HUMAN,tr|E9PMJ1|E9PMJ1_HUMAN,tr|K7EIF2|K7EIF2_HUMAN" 74 1325.6603 1.2 32396 17137 2 1325.656618 663.8374 Ras-related protein Rab-27A OS=Homo sapiens OX=9606 GN=RAB27A PE=1 SV=3 4.37 3005.9 - 1.25E+07 - - - -2.8031 - 2.043 0.466 - 425.8 1 1 0 -0.0037 11 0 0 0 4.32E+08 3.60E+08 - - - 4.4144 0.9999 221125_WJC_METTL3_EV_vs_WT_F03.17138.17138.2 0.00114 13/22 R.STGEAFVQFASK.E sp|P31942|HNRH3_HUMAN 1 1270.6194 2.01 32397 17138 2 1270.618969 636.317 Heterogeneous nuclear ribonucleoprotein H3 OS=Homo sapiens OX=9606 GN=HNRNPH3 PE=1 SV=2 5.72 3005.9 - 8.13E+06 - - - -0.3132 - 2.699 0.535 - 876.6 1 2 0 -0.0004 12 0 0 0 1.90E+08 9.46E+07 - - - 5.6048 0.9998 221125_WJC_METTL3_EV_vs_WT_F03.17139.17139.2 9.69E-07 15/26 K.EIDDSVLGQTGPYR[166.11].R "sp|O43615|TIM44_HUMAN,tr|M0QXU7|M0QXU7_HUMAN" 2 1558.7503 2.29 32398 17139 2 1558.74656 780.3824 Mitochondrial import inner membrane translocase subunit TIM44 OS=Homo sapiens OX=9606 GN=TIMM44 PE=1 SV=2 4.03 3006 - 4.64E+06 - - - -2.3808 - 2.603 0.56 - 685.2 1 2 0 -0.0037 14 0 0 0 2.76E+08 1.20E+08 - - - 5.5767 0.9997 221125_WJC_METTL3_EV_vs_WT_F03.17141.17141.2 0.000522 16-Jul R.WDQSTFIGR.A "sp|Q9H9B4|SFXN1_HUMAN,sp|Q9BWM7|SFXN3_HUMAN,tr|S4R3N9|S4R3N9_HUMAN,tr|D6RFI0|D6RFI0_HUMAN,tr|D6RDG7|D6RDG7_HUMAN,tr|S4R2X2|S4R2X2_HUMAN,tr|D6RAE9|D6RAE9_HUMAN,tr|A0A1P0AYU5|A0A1P0AYU5_HUMAN" 8 1108.5302 1.06 32400 17141 2 1108.531083 555.2724 Sideroflexin-1 OS=Homo sapiens OX=9606 GN=SFXN1 PE=1 SV=4 5.84 3006.1 - 2.38E+06 - - - 0.8344 - 1.536 0.466 - 163.3 1 2 0 0.0009 9 0 0 0 1.98E+07 1.86E+07 - - - 3.7242 0.9997 221125_WJC_METTL3_EV_vs_WT_F03.17142.17142.3 0.909 13/52 R.LLDSVPPTAISHFK.Q sp|Q9NR30|DDX21_HUMAN 1 1523.8348 0.94 32401 17142 3 1523.834534 508.9522 Nucleolar RNA helicase 2 OS=Homo sapiens OX=9606 GN=DDX21 PE=1 SV=5 6.74 3006.1 - 2.37E+06 - - - -0.1614 - 2.325 0.319 - 196.3 1 2 0 -0.0002 14 0 0 0 3.10E+07 3.31E+07 - - - 4.3387 0.9999 221125_WJC_METTL3_EV_vs_WT_F03.17143.17143.3 0.00233 Dec-68 K.TVAGGAWTYNTTSAVTVK[136.11].S "sp|P61513|RL37A_HUMAN,tr|C9J4Z3|C9J4Z3_HUMAN" 2 1833.9352 0.87 32402 17143 3 1833.932641 612.319 60S ribosomal protein L37a OS=Homo sapiens OX=9606 GN=RPL37A PE=1 SV=2 8.26 3006.2 - 2.33E+06 - - - -1.4106 - 2.227 0.427 - 102.7 1 2 0 -0.0026 18 0 0 0 6.03E+07 6.89E+07 - - - 5.2936 0.9999 221125_WJC_METTL3_EV_vs_WT_F03.17146.17146.3 0.00182 13/36 K.EIEAIHAILR.S sp|Q15643|TRIPB_HUMAN 1 1163.6663 1.19 32405 17146 3 1163.665379 388.896 Thyroid receptor-interacting protein 11 OS=Homo sapiens OX=9606 GN=TRIP11 PE=1 SV=3 5.4 3006.5 - 1.55E+06 - - - -0.7554 - 2.019 0.421 - 327.7 1 2 0 -0.0009 10 0 0 0 7.89E+07 6.65E+07 - - - 5.2854 0.9999 221125_WJC_METTL3_EV_vs_WT_F03.17148.17148.3 0.000487 13/52 K.EIDDSVLGQTGPYR.R "sp|O43615|TIM44_HUMAN,tr|M0QXU7|M0QXU7_HUMAN" 2 1548.742 1.49 32407 17148 3 1548.740225 517.2546 Mitochondrial import inner membrane translocase subunit TIM44 OS=Homo sapiens OX=9606 GN=TIMM44 PE=1 SV=2 4.03 3006.7 - 1.25E+06 - - - -1.1467 - 2.041 0.43 - 194.4 1 2 0 -0.0018 14 0 0 0 3.16E+07 2.13E+07 - - - 5.2296 0.9989 221125_WJC_METTL3_EV_vs_WT_F03.17149.17149.3 0.00905 Dec-44 R.IIVSDHVEFPVR.Q "sp|O15397|IPO8_HUMAN,tr|F5H2I3|F5H2I3_HUMAN" 2 1409.7667 3.73 32408 17149 3 1409.761486 470.9295 Importin-8 OS=Homo sapiens OX=9606 GN=IPO8 PE=1 SV=2 5.32 3006.8 - 1.24E+06 - - - -3.6985 - 2.591 0.311 - 246 1 2 0 -0.0052 12 0 0 0 9.64E+06 2.58E+06 - - - 4.6448 1 221125_WJC_METTL3_EV_vs_WT_F03.17150.17150.2 2.02E-11 17/30 K.VFSDEVQQQAQLSTIR[166.11].S "sp|Q9Y262|EIF3L_HUMAN,tr|B0QY89|B0QY89_HUMAN,tr|B0QY90|B0QY90_HUMAN" 3 1857.946 1.09 32409 17150 2 1857.94342 929.9803 Eukaryotic translation initiation factor 3 subunit L OS=Homo sapiens OX=9606 GN=EIF3L PE=1 SV=1 4.37 3006.9 - 1.22E+06 - - - -1.3946 - 3.545 0.71 - 1140.3 1 2 0 -0.0026 16 0 0 0 5.98E+06 5.48E+06 - - - 7.3956 0.9749 221125_WJC_METTL3_EV_vs_WT_F03.17151.17151.2 0.000183 18-Nov A.NVLLQIDNAR.L "sp|P02533|K1C14_HUMAN,sp|Q7Z3Y7|K1C28_HUMAN" 2 1154.6408 999 32410 17151 2 1154.637578 578.3277 "Keratin, type I cytoskeletal 14 OS=Homo sapiens OX=9606 GN=KRT14 PE=1 SV=4" 5.84 3007 - 1.14E+06 - - - -2.7654 - 2.155 0.512 - 497.5 1 1 0 -0.0032 10 0 0 0 3.85E+07 0.00E+00 - - - 4.9648 0.9982 221125_WJC_METTL3_EV_vs_WT_F03.17152.17152.2 0.003 20-Dec R.QLLDQVEQIQK[136.11].E sp|Q7Z7H5|TMED4_HUMAN 1 1348.7442 1.5 32411 17152 2 1348.739196 675.3794 Transmembrane emp24 domain-containing protein 4 OS=Homo sapiens OX=9606 GN=TMED4 PE=1 SV=1 4.37 3007.2 - 974669 - - - -3.6953 - 2.313 0.344 - 268.4 1 2 0 -0.005 11 0 0 0 4.19E+07 2.79E+07 - - - 3.8487 1 221125_WJC_METTL3_EV_vs_WT_F03.17157.17157.3 2.03E-09 14/68 K.TVAGGAWTYNTTSAVTVK.S "sp|P61513|RL37A_HUMAN,tr|C9J4Z3|C9J4Z3_HUMAN" 2 1825.921 0.9 32414 17157 3 1825.920382 609.6476 60S ribosomal protein L37a OS=Homo sapiens OX=9606 GN=RPL37A PE=1 SV=2 8.26 3007.7 - 4.64E+06 - - - -0.3538 - 2.677 0.607 - 149.3 1 2 0 -0.0006 18 0 0 0 7.00E+07 7.74E+07 - - - 7.7593 0.9998 221125_WJC_METTL3_EV_vs_WT_F03.17158.17158.3 0.00801 Dec-36 K.EIEAIHAILR[166.11].S sp|Q15643|TRIPB_HUMAN 1 1173.6745 1.19 32415 17158 3 1173.673057 392.2321 Thyroid receptor-interacting protein 11 OS=Homo sapiens OX=9606 GN=TRIP11 PE=1 SV=3 5.4 3007.8 - 4.00E+06 - - - -1.2533 - 2.055 0.347 - 270.9 1 2 0 -0.0015 10 0 0 0 7.89E+07 6.65E+07 - - - 4.5118 0.9999 221125_WJC_METTL3_EV_vs_WT_F03.17159.17159.3 0.000119 13/40 K.ALDDMISTLK[136.11]K[136.11].L "sp|P49368|TCPG_HUMAN,tr|E9PM09|E9PM09_HUMAN,tr|Q5SZW8|Q5SZW8_HUMAN,tr|E9PRC8|E9PRC8_HUMAN,tr|B4DUR8|B4DUR8_HUMAN,tr|E9PQ35|E9PQ35_HUMAN,tr|Q5SZX6|Q5SZX6_HUMAN" 7 1249.6923 0.22 32416 17159 3 1249.691121 417.5714 T-complex protein 1 subunit gamma OS=Homo sapiens OX=9606 GN=CCT3 PE=1 SV=4 6 3007.9 - 2.89E+06 - - - -0.9226 - 2.445 0.408 - 208.8 1 2 0 -0.0012 11 0 0 0 3.96E+07 1.82E+08 - - - 5.6283 0.9998 221125_WJC_METTL3_EV_vs_WT_F03.17160.17160.2 1.00E-05 18-Oct K.NFEDVAFDEK.K "sp|P07237|PDIA1_HUMAN,tr|A0A7P0TA97|A0A7P0TA97_HUMAN,tr|A0A7P0T8C0|A0A7P0T8C0_HUMAN,tr|H7BZ94|H7BZ94_HUMAN,tr|B3KTQ9|B3KTQ9_HUMAN,tr|A0A7P0TA71|A0A7P0TA71_HUMAN,tr|I3L4M2|I3L4M2_HUMAN,tr|A0A7P0T9D6|A0A7P0T9D6_HUMAN,tr|A0A7P0T9K9|A0A7P0T9K9_HUMAN,tr|H0Y3Z3|H0Y3Z3_HUMAN,tr|A0A7P0TA35|A0A7P0TA35_HUMAN,tr|A0A7P0TB26|A0A7P0TB26_HUMAN,tr|A0A7P0T9U6|A0A7P0T9U6_HUMAN,tr|I3L0S0|I3L0S0_HUMAN,tr|I3L3P5|I3L3P5_HUMAN,tr|A0A7P0T8J3|A0A7P0T8J3_HUMAN,tr|A0A7P0T8X1|A0A7P0T8X1_HUMAN" 17 1212.5299 1.53 32417 17160 2 1212.527436 607.2722 Protein disulfide-isomerase OS=Homo sapiens OX=9606 GN=P4HB PE=1 SV=3 3.92 3007.9 - 2.78E+06 - - - -2.0181 - 2.188 0.593 - 333.8 1 2 0 -0.0024 10 0 0 0 1.14E+08 7.43E+07 - - - 5.6057 0.9998 221125_WJC_METTL3_EV_vs_WT_F03.17163.17163.3 0.00486 Dec-40 K.LQIVEMPLAHK.L "sp|P50454|SERPH_HUMAN,tr|E9PKH2|E9PKH2_HUMAN,tr|E9PPV6|E9PPV6_HUMAN,tr|E9PR70|E9PR70_HUMAN,tr|E9PJH8|E9PJH8_HUMAN" 5 1277.7166 1.58 32420 17163 3 1277.714068 426.9128 Serpin H1 OS=Homo sapiens OX=9606 GN=SERPINH1 PE=1 SV=2 6.75 3008.2 - 1.59E+06 - - - -1.9652 - 2.481 0.365 - 310.8 1 2 0 -0.0025 11 0 0 0 8.30E+07 5.26E+07 - - - 5.19 1 221125_WJC_METTL3_EV_vs_WT_F03.17164.17164.3 0.000542 13/44 R.IHVLEAQDLIAK[136.11].D sp|Q9BSJ8|ESYT1_HUMAN 1 1356.7857 1.28 32421 17164 3 1356.785679 453.2692 Extended synaptotagmin-1 OS=Homo sapiens OX=9606 GN=ESYT1 PE=1 SV=1 5.32 3008.3 - 1.58E+06 - - - 0.0206 - 2.646 0.439 - 371.7 1 2 0 0 12 0 0 0 1.95E+07 1.53E+07 - - - 6.1316 0.9998 221125_WJC_METTL3_EV_vs_WT_F03.17165.17165.2 0.00157 13/18 K.EIEAIHAILR.S sp|Q15643|TRIPB_HUMAN 1 1163.6663 1.11 32422 17165 2 1163.667085 582.8404 Thyroid receptor-interacting protein 11 OS=Homo sapiens OX=9606 GN=TRIP11 PE=1 SV=3 5.4 3008.4 - 1.36E+06 - - - 0.7107 - 2.281 0.441 - 709.5 1 2 0 0.0008 10 0 0 0 2.18E+07 1.96E+07 - - - 4.5997 0.9999 221125_WJC_METTL3_EV_vs_WT_F03.17166.17166.2 9.18E-09 18/28 R.GALQNIIPASTGAAK.A "sp|P04406|G3P_HUMAN,tr|E7EUT5|E7EUT5_HUMAN" 2 1410.7831 1.16 32423 17166 2 1410.782178 706.3988 Glyceraldehyde-3-phosphate dehydrogenase OS=Homo sapiens OX=9606 GN=GAPDH PE=1 SV=3 8.75 3008.6 - 1.32E+06 - - - -0.6379 - 2.83 0.537 - 826.4 1 2 0 -0.0009 15 0 0 0 5.77E+08 4.98E+08 - - - 5.5646 0.9013 221125_WJC_METTL3_EV_vs_WT_F03.17167.17167.2 0.00115 22-Sep V.ATKPLYVALAQR.K "sp|Q9H361|PABP3_HUMAN,sp|P11940|PABP1_HUMAN,tr|A0A7I2YQE4|A0A7I2YQE4_HUMAN,tr|A0A7I2V649|A0A7I2V649_HUMAN,tr|H0YB86|H0YB86_HUMAN,tr|H0YAR2|H0YAR2_HUMAN,tr|E7ERJ7|E7ERJ7_HUMAN,tr|A0A7I2YQ88|A0A7I2YQ88_HUMAN,tr|A0A087WTT1|A0A087WTT1_HUMAN,tr|A0A7I2YQ90|A0A7I2YQ90_HUMAN,tr|A0A7I2V4N4|A0A7I2V4N4_HUMAN,tr|E7EQV3|E7EQV3_HUMAN" 12 1329.7769 1.76 32424 17167 2 1329.773008 665.8957 Polyadenylate-binding protein 3 OS=Homo sapiens OX=9606 GN=PABPC3 PE=1 SV=2 9.99 3008.6 - 3.09E+06 - - - -2.905 - 1.599 0.391 - 162.6 1 1 0 -0.0039 12 0 0 0 2.57E+07 1.46E+07 - - - 3.1627 1 221125_WJC_METTL3_EV_vs_WT_F03.17168.17168.2 4.47E-07 17/30 K.AGFSGGMVVDYPNSAK[136.11].A "sp|O43709|BUD23_HUMAN,tr|H7C170|H7C170_HUMAN" 2 1606.7541 0.45 32425 17168 2 1606.757618 804.3843 Probable 18S rRNA (guanine-N(7))-methyltransferase OS=Homo sapiens OX=9606 GN=BUD23 PE=1 SV=2 5.88 3008.7 - 827164 - - - 2.1939 - 3.076 0.584 - 623.8 1 2 0 0.0035 16 0 0 0 6.12E+06 1.35E+07 - - - 6.1158 0.9561 221125_WJC_METTL3_EV_vs_WT_F03.17170.17170.3 0.00041 Dec-40 H.LQLWDTAGQER[166.11].F "sp|P51159|RB27A_HUMAN,sp|Q9H082|RB33B_HUMAN,sp|P20336|RAB3A_HUMAN,sp|Q8IZ41|RASEF_HUMAN,sp|P20337|RAB3B_HUMAN,sp|Q96E17|RAB3C_HUMAN,sp|P61006|RAB8A_HUMAN,sp|P61026|RAB10_HUMAN,sp|Q15286|RAB35_HUMAN,sp|O00194|RB27B_HUMAN,sp|Q14964|RB39A_HUMAN,sp|Q9H0U4|RAB1B_HUMAN,sp|P61018|RAB4B_HUMAN,sp|P59190|RAB15_HUMAN,sp|Q9BZG1|RAB34_HUMAN,sp|Q9NP90|RAB9B_HUMAN,sp|Q9BSW2|EFC4B_HUMAN,sp|P20338|RAB4A_HUMAN,sp|Q15771|RAB30_HUMAN,sp|P62820|RAB1A_HUMAN,sp|Q5JT25|RAB41_HUMAN,sp|Q86YS6|RAB43_HUMAN,sp|Q96DA2|RB39B_HUMAN,sp|P20340|RAB6A_HUMAN,sp|Q96AX2|RAB37_HUMAN,sp|Q7Z6P3|RAB44_HUMAN,sp|Q9NRW1|RAB6B_HUMAN,sp|O95716|RAB3D_HUMAN,sp|Q6IQ22|RAB12_HUMAN,sp|Q92930|RAB8B_HUMAN,sp|Q92928|RAB1C_HUMAN,sp|P61106|RAB14_HUMAN,tr|A8MZI4|A8MZI4_HUMAN,tr|A0A494C0Z5|A0A494C0Z5_HUMAN,tr|H3BVH7|H3BVH7_HUMAN,tr|E9PJQ5|E9PJQ5_HUMAN,tr|H0YMN7|H0YMN7_HUMAN,tr|C9JBG0|C9JBG0_HUMAN,tr|A8MTC6|A8MTC6_HUMAN,tr|B7Z3L0|B7Z3L0_HUMAN,tr|E9PS06|E9PS06_HUMAN,tr|A0A2R8Y7G7|A0A2R8Y7G7_HUMAN,tr|A8MSP2|A8MSP2_HUMAN,tr|E9PNB9|E9PNB9_HUMAN,tr|E9PLM3|E9PLM3_HUMAN,tr|H0YNE9|H0YNE9_HUMAN,tr|E9PI18|E9PI18_HUMAN,tr|G3V196|G3V196_HUMAN,tr|X6RFL8|X6RFL8_HUMAN,tr|Q6PIK3|Q6PIK3_HUMAN,tr|A0A3B3ITT1|A0A3B3ITT1_HUMAN,tr|Q96PJ7|Q96PJ7_HUMAN,tr|C9JB90|C9JB90_HUMAN,tr|J3KR73|J3KR73_HUMAN,tr|A0A2R8YFB8|A0A2R8YFB8_HUMAN,tr|H3BUD9|H3BUD9_HUMAN,tr|J3QLC6|J3QLC6_HUMAN,tr|M0R257|M0R257_HUMAN,tr|J3QSF4|J3QSF4_HUMAN,tr|E7ES60|E7ES60_HUMAN,tr|H0YDK7|H0YDK7_HUMAN,tr|C9JFM7|C9JFM7_HUMAN,tr|H3BS49|H3BS49_HUMAN,tr|M0R0X1|M0R0X1_HUMAN,tr|C9JY26|C9JY26_HUMAN,tr|K7ES41|K7ES41_HUMAN,tr|H3BN55|H3BN55_HUMAN,tr|H7C0Y7|H7C0Y7_HUMAN,tr|C9JU14|C9JU14_HUMAN,tr|E9PRF7|E9PRF7_HUMAN,tr|G3V562|G3V562_HUMAN,tr|F5H157|F5H157_HUMAN,tr|E9PMJ1|E9PMJ1_HUMAN,tr|K7EIF2|K7EIF2_HUMAN" 74 1325.6603 1.15 32427 17170 3 1325.658976 442.8941 Ras-related protein Rab-27A OS=Homo sapiens OX=9606 GN=RAB27A PE=1 SV=3 4.37 3009 - 730863 - - - -1.0244 - 2.237 0.279 - 284.6 1 1 0 -0.0014 11 0 0 0 7.97E+06 6.95E+06 - - - 3.9375 0.9999 221125_WJC_METTL3_EV_vs_WT_F03.17175.17175.2 7.79E-07 13/24 K.QISQAYEVLSDAK[136.11].K sp|P31689|DNJA1_HUMAN 1 1458.7446 0.49 32430 17175 2 1458.742801 730.3796 DnaJ homolog subfamily A member 1 OS=Homo sapiens OX=9606 GN=DNAJA1 PE=1 SV=2 4.37 3009.6 - 4.10E+06 - - - -1.2154 - 2.62 0.564 - 546.2 1 2 0 -0.0018 13 0 0 0 1.53E+08 3.13E+08 - - - 5.6782 1 221125_WJC_METTL3_EV_vs_WT_F03.17178.17178.3 3.17E-08 14/44 R.IHVLEAQDLIAK.D sp|Q9BSJ8|ESYT1_HUMAN 1 1348.7715 1.28 32433 17178 3 1348.770967 450.5978 Extended synaptotagmin-1 OS=Homo sapiens OX=9606 GN=ESYT1 PE=1 SV=1 5.32 3009.8 - 2.31E+06 - - - -0.3588 - 2.94 0.537 - 424.2 1 2 0 -0.0005 12 0 0 0 1.95E+07 1.53E+07 - - - 7.5161 0.9998 221125_WJC_METTL3_EV_vs_WT_F03.17179.17179.2 4.72E-06 18-Nov R.EGELYFPEDR.E "sp|Q9Y6J9|TAF6L_HUMAN,tr|E9PP94|E9PP94_HUMAN" 2 1253.5564 1.12 32434 17179 2 1253.554562 627.7855 TAF6-like RNA polymerase II p300\CBP-associated factor-associated factor 65 kDa subunit 6L OS=Homo sapiens OX=9606 GN=TAF6L PE=1 SV=1 4 3009.9 - 2.23E+06 - - - -1.4918 - 2.215 0.532 - 669.9 1 2 0 -0.0019 10 0 0 0 1.90E+07 1.70E+07 - - - 5.1896 0.9997 221125_WJC_METTL3_EV_vs_WT_F03.17181.17181.3 0.000324 13/36 K.LDPELHLDIK.V "sp|Q12905|ILF2_HUMAN,tr|B4DY09|B4DY09_HUMAN" 2 1191.6499 1.32 32436 17181 3 1191.646016 398.2239 Interleukin enhancer-binding factor 2 OS=Homo sapiens OX=9606 GN=ILF2 PE=1 SV=2 4.54 3010 - 2.13E+06 - - - -3.2921 - 2.464 0.412 - 171.2 1 2 0 -0.0039 10 0 0 0 2.14E+07 1.62E+07 - - - 5.7659 0.9998 221125_WJC_METTL3_EV_vs_WT_F03.17182.17182.3 0.00065 Nov-40 K.LQIVEMPLAHK[136.11].L "sp|P50454|SERPH_HUMAN,tr|E9PKH2|E9PKH2_HUMAN,tr|E9PPV6|E9PPV6_HUMAN,tr|E9PR70|E9PR70_HUMAN,tr|E9PJH8|E9PJH8_HUMAN" 5 1285.7308 1.58 32437 17182 3 1285.728213 429.5842 Serpin H1 OS=Homo sapiens OX=9606 GN=SERPINH1 PE=1 SV=2 6.75 3010.1 - 1.95E+06 - - - -1.9958 - 2.449 0.346 - 224.7 1 2 0 -0.0026 11 0 0 0 8.30E+07 5.26E+07 - - - 4.9413 0.9999 221125_WJC_METTL3_EV_vs_WT_F03.17183.17183.2 0.000138 13/18 R.EGELYFPEDR[166.11].E "sp|Q9Y6J9|TAF6L_HUMAN,tr|E9PP94|E9PP94_HUMAN" 2 1263.5647 1.09 32438 17183 2 1263.564645 632.7896 TAF6-like RNA polymerase II p300\CBP-associated factor-associated factor 65 kDa subunit 6L OS=Homo sapiens OX=9606 GN=TAF6L PE=1 SV=1 4 3010.2 - 1.37E+06 - - - -0.0451 - 2.514 0.396 - 1077.5 1 2 0 -0.0001 10 0 0 0 1.86E+07 1.70E+07 - - - 4.5391 0.974 221125_WJC_METTL3_EV_vs_WT_F03.17184.17184.3 0.000132 Sep-40 H.LQLWDTAGQER.F "sp|P51159|RB27A_HUMAN,sp|Q9H082|RB33B_HUMAN,sp|P20336|RAB3A_HUMAN,sp|Q8IZ41|RASEF_HUMAN,sp|P20337|RAB3B_HUMAN,sp|Q96E17|RAB3C_HUMAN,sp|P61006|RAB8A_HUMAN,sp|P61026|RAB10_HUMAN,sp|Q15286|RAB35_HUMAN,sp|O00194|RB27B_HUMAN,sp|Q14964|RB39A_HUMAN,sp|Q9H0U4|RAB1B_HUMAN,sp|P61018|RAB4B_HUMAN,sp|P59190|RAB15_HUMAN,sp|Q9BZG1|RAB34_HUMAN,sp|Q9NP90|RAB9B_HUMAN,sp|Q9BSW2|EFC4B_HUMAN,sp|P20338|RAB4A_HUMAN,sp|Q15771|RAB30_HUMAN,sp|P62820|RAB1A_HUMAN,sp|Q5JT25|RAB41_HUMAN,sp|Q86YS6|RAB43_HUMAN,sp|Q96DA2|RB39B_HUMAN,sp|P20340|RAB6A_HUMAN,sp|Q96AX2|RAB37_HUMAN,sp|Q7Z6P3|RAB44_HUMAN,sp|Q9NRW1|RAB6B_HUMAN,sp|O95716|RAB3D_HUMAN,sp|Q6IQ22|RAB12_HUMAN,sp|Q92930|RAB8B_HUMAN,sp|Q92928|RAB1C_HUMAN,sp|P61106|RAB14_HUMAN,tr|A8MZI4|A8MZI4_HUMAN,tr|A0A494C0Z5|A0A494C0Z5_HUMAN,tr|H3BVH7|H3BVH7_HUMAN,tr|E9PJQ5|E9PJQ5_HUMAN,tr|H0YMN7|H0YMN7_HUMAN,tr|C9JBG0|C9JBG0_HUMAN,tr|A8MTC6|A8MTC6_HUMAN,tr|B7Z3L0|B7Z3L0_HUMAN,tr|E9PS06|E9PS06_HUMAN,tr|A0A2R8Y7G7|A0A2R8Y7G7_HUMAN,tr|A8MSP2|A8MSP2_HUMAN,tr|E9PNB9|E9PNB9_HUMAN,tr|E9PLM3|E9PLM3_HUMAN,tr|H0YNE9|H0YNE9_HUMAN,tr|E9PI18|E9PI18_HUMAN,tr|G3V196|G3V196_HUMAN,tr|X6RFL8|X6RFL8_HUMAN,tr|Q6PIK3|Q6PIK3_HUMAN,tr|A0A3B3ITT1|A0A3B3ITT1_HUMAN,tr|Q96PJ7|Q96PJ7_HUMAN,tr|C9JB90|C9JB90_HUMAN,tr|J3KR73|J3KR73_HUMAN,tr|A0A2R8YFB8|A0A2R8YFB8_HUMAN,tr|H3BUD9|H3BUD9_HUMAN,tr|J3QLC6|J3QLC6_HUMAN,tr|M0R257|M0R257_HUMAN,tr|J3QSF4|J3QSF4_HUMAN,tr|E7ES60|E7ES60_HUMAN,tr|H0YDK7|H0YDK7_HUMAN,tr|C9JFM7|C9JFM7_HUMAN,tr|H3BS49|H3BS49_HUMAN,tr|M0R0X1|M0R0X1_HUMAN,tr|C9JY26|C9JY26_HUMAN,tr|K7ES41|K7ES41_HUMAN,tr|H3BN55|H3BN55_HUMAN,tr|H7C0Y7|H7C0Y7_HUMAN,tr|C9JU14|C9JU14_HUMAN,tr|E9PRF7|E9PRF7_HUMAN,tr|G3V562|G3V562_HUMAN,tr|F5H157|F5H157_HUMAN,tr|E9PMJ1|E9PMJ1_HUMAN,tr|K7EIF2|K7EIF2_HUMAN" 74 1315.6521 1.15 32439 17184 3 1315.649565 439.558 Ras-related protein Rab-27A OS=Homo sapiens OX=9606 GN=RAB27A PE=1 SV=3 4.37 3010.3 - 1.18E+06 - - - -1.8994 - 1.971 0.39 - 152.2 1 1 0 -0.0025 11 0 0 0 7.97E+06 6.95E+06 - - - 4.815 0.9996 221125_WJC_METTL3_EV_vs_WT_F03.17185.17185.3 0.0226 Oct-44 R.DIKPDNLLLDSK.G sp|Q15208|STK38_HUMAN 1 1369.7453 3.14 32440 17185 3 1369.744247 457.589 Serine\threonine-protein kinase 38 OS=Homo sapiens OX=9606 GN=STK38 PE=1 SV=1 4.43 3010.4 - 971544 - - - -0.7658 - 1.958 0.322 - 171.2 1 2 0 -0.001 12 0 0 0 1.08E+07 3.43E+06 - - - 3.9922 0.9993 221125_WJC_METTL3_EV_vs_WT_F03.17186.17186.2 0.000557 16-Aug K.FNPFVTSDR.S "sp|Q9UNX3|RL26L_HUMAN,sp|P61254|RL26_HUMAN,tr|J3QQQ9|J3QQQ9_HUMAN,tr|E5RIT6|E5RIT6_HUMAN,tr|E5RHH1|E5RHH1_HUMAN,tr|J3QQV1|J3QQV1_HUMAN,tr|J3KSS0|J3KSS0_HUMAN,tr|J3QRC4|J3QRC4_HUMAN,tr|J3QRI7|J3QRI7_HUMAN" 9 1081.5193 1.45 32441 17186 2 1081.520919 541.7669 60S ribosomal protein L26-like 1 OS=Homo sapiens OX=9606 GN=RPL26L1 PE=1 SV=1 5.84 3010.6 - 808653 - - - 1.5349 - 1.484 0.422 - 202.8 1 2 0 0.0017 9 0 0 0 8.96E+06 6.17E+06 - - - 3.2994 0.9997 221125_WJC_METTL3_EV_vs_WT_F03.17189.17189.2 8.32E-05 16-Jul R.EYQDLLNVK[136.11].M "sp|P08670|VIME_HUMAN,sp|P14136|GFAP_HUMAN,sp|P17661|DESM_HUMAN,sp|Q16352|AINX_HUMAN,sp|P07197|NFM_HUMAN,sp|P12036|NFH_HUMAN,sp|P07196|NFL_HUMAN,tr|A0A1W2PR46|A0A1W2PR46_HUMAN,tr|A0A1X7SBR3|A0A1X7SBR3_HUMAN,tr|K7EJU1|K7EJU1_HUMAN,tr|A0A1X7SCE1|A0A1X7SCE1_HUMAN,tr|A0A1W2PRT3|A0A1W2PRT3_HUMAN,tr|B0YJC5|B0YJC5_HUMAN,tr|B0YJC4|B0YJC4_HUMAN,tr|E7ESP9|E7ESP9_HUMAN,tr|E7EMV2|E7EMV2_HUMAN" 16 1128.5906 2 32443 17189 2 1128.589156 565.3026 Vimentin OS=Homo sapiens OX=9606 GN=VIM PE=1 SV=4 4.37 3010.9 - 4.08E+07 - - - -1.3149 - 1.477 0.541 - 222.7 1 2 0 -0.0015 9 0 0 0 2.51E+09 1.26E+09 - - - 4.1647 0.9999 221125_WJC_METTL3_EV_vs_WT_F03.17190.17190.2 1.47E-05 13/20 R.QLLDQVEQIQK.E sp|Q7Z7H5|TMED4_HUMAN 1 1340.73 1.05 32444 17190 2 1340.729058 671.3723 Transmembrane emp24 domain-containing protein 4 OS=Homo sapiens OX=9606 GN=TMED4 PE=1 SV=1 4.37 3010.9 - 3.93E+06 - - - -0.6877 - 2.713 0.428 - 743.6 1 2 0 -0.0009 11 0 0 0 4.62E+07 4.39E+07 - - - 4.9019 1 221125_WJC_METTL3_EV_vs_WT_F03.17191.17191.2 1.64E-07 24-Dec K.QISQAYEVLSDAK.K sp|P31689|DNJA1_HUMAN 1 1450.7304 0.49 32445 17191 2 1450.72969 726.3725 DnaJ homolog subfamily A member 1 OS=Homo sapiens OX=9606 GN=DNAJA1 PE=1 SV=2 4.37 3011 - 4.57E+06 - - - -0.4715 - 2.65 0.637 - 476.6 1 2 0 -0.0007 13 0 0 0 1.53E+08 3.13E+08 - - - 6.2469 0.9999 221125_WJC_METTL3_EV_vs_WT_F03.17192.17192.2 0.000117 18-Nov K.NQVSLTC[160.03]LVK.G "sp|P01859|IGHG2_HUMAN,sp|P01860|IGHG3_HUMAN,sp|P01861|IGHG4_HUMAN,sp|P01857|IGHG1_HUMAN,tr|A0A4W9A917|A0A4W9A917_HUMAN,tr|A0A286YES1|A0A286YES1_HUMAN,tr|A0A0A0MS08|A0A0A0MS08_HUMAN,tr|A0A286YFJ8|A0A286YFJ8_HUMAN,tr|A0A0A0MS07|A0A0A0MS07_HUMAN,tr|A0A286YEY4|A0A286YEY4_HUMAN" 10 1160.6223 31.43 32446 17192 2 1160.621455 581.3184 Immunoglobulin heavy constant gamma 2 OS=Homo sapiens OX=9606 GN=IGHG2 PE=1 SV=2 8.22 3011.1 - 2.71E+06 - - - -0.766 - 2.225 0.483 - 578.1 1 2 0 -0.0009 10 0 0 0 5.31E+07 1.69E+06 - - - 4.8405 0.9932 221125_WJC_METTL3_EV_vs_WT_F03.17194.17194.2 4.64E-05 14/24 L.VATKPLYVALAQR.K "sp|Q9H361|PABP3_HUMAN,sp|P11940|PABP1_HUMAN,tr|A0A7I2YQE4|A0A7I2YQE4_HUMAN,tr|A0A7I2V649|A0A7I2V649_HUMAN,tr|H0YB86|H0YB86_HUMAN,tr|H0YAR2|H0YAR2_HUMAN,tr|E7ERJ7|E7ERJ7_HUMAN,tr|A0A7I2YQ88|A0A7I2YQ88_HUMAN,tr|A0A087WTT1|A0A087WTT1_HUMAN,tr|A0A7I2YQ90|A0A7I2YQ90_HUMAN,tr|A0A7I2V4N4|A0A7I2V4N4_HUMAN,tr|E7EQV3|E7EQV3_HUMAN" 12 1428.8453 1.98 32448 17194 2 1428.843989 715.4299 Polyadenylate-binding protein 3 OS=Homo sapiens OX=9606 GN=PABPC3 PE=1 SV=2 9.99 3011.3 - 1.23E+06 - - - -0.907 - 2.507 0.519 - 368.7 1 1 0 -0.0013 13 0 0 0 1.13E+07 5.70E+06 - - - 5.2328 0.9995 221125_WJC_METTL3_EV_vs_WT_F03.17195.17195.3 0.00382 Dec-40 K.AIYHLEAFVAK.F sp|P40938|RFC3_HUMAN 1 1260.6867 1.11 32449 17195 3 1260.687177 421.2362 Replication factor C subunit 3 OS=Homo sapiens OX=9606 GN=RFC3 PE=1 SV=2 6.79 3011.5 - 600976 - - - 0.4109 - 1.634 0.343 - 82 1 2 0 0.0005 11 0 0 0 4.84E+06 4.36E+06 - - - 3.7589 0.9999 221125_WJC_METTL3_EV_vs_WT_F03.17200.17200.3 7.38E-06 16/60 K.IFVGGIKEDTEEYNLR.D "sp|P51991|ROA3_HUMAN,tr|A0A7I2V5D8|A0A7I2V5D8_HUMAN,tr|A0A7I2V2R3|A0A7I2V2R3_HUMAN,tr|A0A7I2V4J6|A0A7I2V4J6_HUMAN,tr|A0A7I2V4G0|A0A7I2V4G0_HUMAN,tr|A0A7I2V402|A0A7I2V402_HUMAN" 6 1881.9472 1.32 32452 17200 3 1881.945907 628.323 Heterogeneous nuclear ribonucleoprotein A3 OS=Homo sapiens OX=9606 GN=HNRNPA3 PE=1 SV=2 4.41 3012 - 3.57E+06 - - - -0.7099 - 3.117 0.535 - 309.7 1 2 1 -0.0013 16 0 0 0 4.41E+08 3.34E+08 - - - 7.4214 0.9709 221125_WJC_METTL3_EV_vs_WT_F03.17202.17202.2 0.00012 16-Aug W.GNVGFVFTK.E "sp|Q8NHW5|RLA0L_HUMAN,sp|P05388|RLA0_HUMAN,tr|G3V210|G3V210_HUMAN,tr|F8VU65|F8VU65_HUMAN,tr|F8VWV4|F8VWV4_HUMAN,tr|F8VWS0|F8VWS0_HUMAN,tr|F8VS58|F8VS58_HUMAN,tr|F8VW21|F8VW21_HUMAN,tr|F8VZS0|F8VZS0_HUMAN,tr|F8VRK7|F8VRK7_HUMAN,tr|F8VQY6|F8VQY6_HUMAN,tr|F8VPE8|F8VPE8_HUMAN" 12 967.5127 0.96 32454 17202 2 967.512632 484.7636 60S acidic ribosomal protein P0-like OS=Homo sapiens OX=9606 GN=RPLP0P6 PE=5 SV=1 8.75 3012.1 - 2.81E+06 - - - -0.0879 - 1.768 0.315 - 240.5 1 1 0 -0.0001 9 0 0 0 2.74E+07 2.85E+07 - - - 3.0162 0.9999 221125_WJC_METTL3_EV_vs_WT_F03.17203.17203.2 1.93E-06 13/20 R.NATDAVGIVLK.E "sp|P51398|RT29_HUMAN,tr|V9GY11|V9GY11_HUMAN,tr|V9GYA7|V9GYA7_HUMAN,tr|V9GYJ9|V9GYJ9_HUMAN,tr|V9GYW1|V9GYW1_HUMAN,tr|V9GZ03|V9GZ03_HUMAN,tr|V9GYC9|V9GYC9_HUMAN,tr|V9GYL9|V9GYL9_HUMAN" 8 1099.6237 1.29 32455 17203 2 1099.623059 550.8191 "28S ribosomal protein S29, mitochondrial OS=Homo sapiens OX=9606 GN=DAP3 PE=1 SV=1" 5.84 3012.2 - 1.89E+06 - - - -0.6048 - 2.519 0.521 - 535.3 1 2 0 -0.0007 11 0 0 0 3.09E+07 2.40E+07 - - - 5.3882 0.9934 221125_WJC_METTL3_EV_vs_WT_F03.17204.17204.2 4.65E-06 13/22 Q.EPGEVVDSLVGK.Q "sp|Q56A73|SPIN4_HUMAN,sp|Q9Y657|SPIN1_HUMAN" 2 1227.6347 1.66 32456 17204 2 1227.633681 614.8246 Spindlin-4 OS=Homo sapiens OX=9606 GN=SPIN4 PE=1 SV=1 4.14 3012.4 - 1.71E+06 - - - -0.8162 - 2.403 0.526 - 515.5 1 1 0 -0.001 12 0 0 0 2.58E+07 1.56E+07 - - - 5.2325 0.9998 221125_WJC_METTL3_EV_vs_WT_F03.17205.17205.2 0.00154 20-Dec R.NATDAVGIVLK[136.11].E "sp|P51398|RT29_HUMAN,tr|V9GY11|V9GY11_HUMAN,tr|V9GYA7|V9GYA7_HUMAN,tr|V9GYJ9|V9GYJ9_HUMAN,tr|V9GYW1|V9GYW1_HUMAN,tr|V9GZ03|V9GZ03_HUMAN,tr|V9GYC9|V9GYC9_HUMAN,tr|V9GYL9|V9GYL9_HUMAN" 8 1107.6379 1.29 32457 17205 2 1107.638816 554.8262 "28S ribosomal protein S29, mitochondrial OS=Homo sapiens OX=9606 GN=DAP3 PE=1 SV=1" 5.84 3012.5 - 1.63E+06 - - - 0.8053 - 2.221 0.416 - 490.8 1 2 0 0.0009 11 0 0 0 3.09E+07 2.40E+07 - - - 4.272 0.9998 221125_WJC_METTL3_EV_vs_WT_F03.17206.17206.2 0.000118 18-Dec K.EIEAIHAILR[166.11].S sp|Q15643|TRIPB_HUMAN 1 1173.6745 1.11 32458 17206 2 1173.673279 587.8445 Thyroid receptor-interacting protein 11 OS=Homo sapiens OX=9606 GN=TRIP11 PE=1 SV=3 5.4 3012.6 - 1.51E+06 - - - -1.0642 - 2.277 0.474 - 657.3 1 2 0 -0.0012 10 0 0 0 2.18E+07 1.96E+07 - - - 4.8384 1 221125_WJC_METTL3_EV_vs_WT_F03.17209.17209.2 6.67E-08 14/24 R.VLDDGELLVQQTK[136.11].N "sp|P46459|NSF_HUMAN,tr|I3L0N3|I3L0N3_HUMAN" 2 1464.7915 1.51 32461 17209 2 1464.789075 733.403 Vesicle-fusing ATPase OS=Homo sapiens OX=9606 GN=NSF PE=1 SV=3 4.03 3013 - 1.11E+06 - - - -1.6719 - 2.743 0.582 - 493.3 1 2 0 -0.0024 13 0 0 0 3.36E+07 2.22E+07 - - - 5.9286 0.9995 221125_WJC_METTL3_EV_vs_WT_F03.17212.17212.2 0.0239 16-Oct K.SNIDALLSR[166.11].L "sp|Q9UKM9|RALY_HUMAN,tr|Q5QPM0|Q5QPM0_HUMAN,tr|Q5QPL9|Q5QPL9_HUMAN" 3 997.5432 1.12 32464 17212 2 997.542199 499.7789 RNA-binding protein Raly OS=Homo sapiens OX=9606 GN=RALY PE=1 SV=1 5.55 3013.3 - 787839 - - - -0.9824 - 1.858 0.316 - 499.8 1 2 0 -0.001 9 0 0 0 3.32E+07 2.95E+07 - - - 3.1669 0.9988 221125_WJC_METTL3_EV_vs_WT_F03.17213.17213.2 0.00102 20-Sep R.DGMSVYDSLDK[136.11].A sp|P10398|ARAF_HUMAN 1 1236.5424 0.36 32465 17213 2 1236.53903 619.2785 Serine\threonine-protein kinase A-Raf OS=Homo sapiens OX=9606 GN=ARAF PE=1 SV=2 3.93 3013.5 - 698473 - - - -2.7003 - 1.65 0.411 - 188.5 1 2 0 -0.0033 11 0 0 0 1.38E+06 3.86E+06 - - - 3.4303 0.9999 221125_WJC_METTL3_EV_vs_WT_F03.17216.17216.3 1.82E-05 14/60 K.IFVGGIK[136.11]EDTEEYNLR[166.11].D "sp|P51991|ROA3_HUMAN,tr|A0A7I2V5D8|A0A7I2V5D8_HUMAN,tr|A0A7I2V2R3|A0A7I2V2R3_HUMAN,tr|A0A7I2V4J6|A0A7I2V4J6_HUMAN,tr|A0A7I2V4G0|A0A7I2V4G0_HUMAN,tr|A0A7I2V402|A0A7I2V402_HUMAN" 6 1899.9697 1.32 32466 17216 3 1899.967493 634.3305 Heterogeneous nuclear ribonucleoprotein A3 OS=Homo sapiens OX=9606 GN=HNRNPA3 PE=1 SV=2 4.41 3013.8 - 1.61E+07 - - - -1.1684 - 2.702 0.578 - 209.2 1 2 1 -0.0022 16 0 0 0 4.41E+08 3.34E+08 - - - 7.534 1 221125_WJC_METTL3_EV_vs_WT_F03.17217.17217.2 6.24E-07 14/24 K.ELENANDLLSATK.R sp|P12270|TPR_HUMAN 1 1416.7096 5.11 32467 17217 2 1416.708741 709.3621 Nucleoprotein TPR OS=Homo sapiens OX=9606 GN=TPR PE=1 SV=3 4.14 3013.9 - 4.90E+06 - - - -0.6339 - 2.662 0.577 - 513.5 1 2 0 -0.0009 13 0 0 0 8.50E+07 1.66E+07 - - - 5.8153 0.9996 221125_WJC_METTL3_EV_vs_WT_F03.17219.17219.3 0.000145 Dec-48 K.QISQAYEVLSDAK[136.11].K sp|P31689|DNJA1_HUMAN 1 1458.7446 0.47 32469 17219 3 1458.741979 487.2555 DnaJ homolog subfamily A member 1 OS=Homo sapiens OX=9606 GN=DNAJA1 PE=1 SV=2 4.37 3014 - 3.31E+06 - - - -1.7789 - 2.074 0.34 - 154.4 1 2 0 -0.0026 13 0 0 0 1.45E+07 3.07E+07 - - - 4.3078 0.9998 221125_WJC_METTL3_EV_vs_WT_F03.17220.17220.2 0.000616 14/24 R.LQGEVVAFDYQSK[136.11].M "sp|Q3MHD2|LSM12_HUMAN,tr|K7ELG9|K7ELG9_HUMAN" 2 1490.7497 0.04 32470 17220 2 1490.748817 746.3821 Protein LSM12 homolog OS=Homo sapiens OX=9606 GN=LSM12 PE=1 SV=2 4.37 3014.1 - 3.23E+06 - - - -0.5648 - 2.497 0.409 - 750.8 1 2 0 -0.0008 13 0 0 0 2.70E+06 6.15E+07 - - - 4.4102 1 221125_WJC_METTL3_EV_vs_WT_F03.17226.17226.2 3.52E-12 19/32 K.VVQNDAYTAPALPSSIR.T "sp|Q9BY77|PDIP3_HUMAN,tr|F6VRR5|F6VRR5_HUMAN,tr|F8WCX5|F8WCX5_HUMAN,tr|Q8WUT1|Q8WUT1_HUMAN" 4 1800.937 1.55 32476 17226 2 1800.935108 901.4758 Polymerase delta-interacting protein 3 OS=Homo sapiens OX=9606 GN=POLDIP3 PE=1 SV=2 5.81 3014.6 - 1.26E+06 - - - -1.0578 - 3.331 0.687 - 852.4 1 2 0 -0.0019 17 0 0 0 2.12E+08 1.37E+08 - - - 7.0729 0.9967 221125_WJC_METTL3_EV_vs_WT_F03.17227.17227.2 0.00094 20-Nov K.ALDDMISTLKK.L "sp|P49368|TCPG_HUMAN,tr|E9PM09|E9PM09_HUMAN,tr|Q5SZW8|Q5SZW8_HUMAN,tr|E9PRC8|E9PRC8_HUMAN,tr|B4DUR8|B4DUR8_HUMAN,tr|E9PQ35|E9PQ35_HUMAN,tr|Q5SZX6|Q5SZX6_HUMAN" 7 1233.6639 0.29 32477 17227 2 1233.659694 617.8392 T-complex protein 1 subunit gamma OS=Homo sapiens OX=9606 GN=CCT3 PE=1 SV=4 6 3014.7 - 1.23E+06 - - - -3.3883 - 2.088 0.257 - 257.4 1 2 0 -0.0042 11 0 0 0 8.17E+06 2.82E+07 - - - 2.9295 1 221125_WJC_METTL3_EV_vs_WT_F03.17228.17228.3 7.91E-07 21/64 K.VVQNDAYTAPALPSSIR[166.11].T "sp|Q9BY77|PDIP3_HUMAN,tr|F6VRR5|F6VRR5_HUMAN,tr|F8WCX5|F8WCX5_HUMAN,tr|Q8WUT1|Q8WUT1_HUMAN" 4 1810.9453 84 32478 17228 3 1810.944721 604.6557 Polymerase delta-interacting protein 3 OS=Homo sapiens OX=9606 GN=POLDIP3 PE=1 SV=2 5.81 3014.8 - 1.22E+06 - - - -0.3103 - 2.761 0.518 - 493.8 1 2 0 -0.0006 17 0 0 0 8.79E+09 1.05E+08 - - - 6.8807 1 221125_WJC_METTL3_EV_vs_WT_F03.17233.17233.2 6.84E-05 20/32 K.VVQNDAYTAPALPSSIR[166.11].T "sp|Q9BY77|PDIP3_HUMAN,tr|F6VRR5|F6VRR5_HUMAN,tr|F8WCX5|F8WCX5_HUMAN,tr|Q8WUT1|Q8WUT1_HUMAN" 4 1810.9453 1.55 32483 17233 2 1810.942637 906.4799 Polymerase delta-interacting protein 3 OS=Homo sapiens OX=9606 GN=POLDIP3 PE=1 SV=2 5.81 3015.5 - 917238 - - - -1.4611 - 3.403 0.597 - 1090.2 1 2 0 -0.0026 17 0 0 0 2.12E+08 1.37E+08 - - - 6.4605 0.9991 221125_WJC_METTL3_EV_vs_WT_F03.17235.17235.2 0.228 20-Sep K.LQIVEMPLAHK[136.11].L "sp|P50454|SERPH_HUMAN,tr|E9PKH2|E9PKH2_HUMAN,tr|E9PPV6|E9PPV6_HUMAN,tr|E9PR70|E9PR70_HUMAN,tr|E9PJH8|E9PJH8_HUMAN" 5 1285.7308 0.43 32485 17235 2 1285.730882 643.8727 Serpin H1 OS=Homo sapiens OX=9606 GN=SERPINH1 PE=1 SV=2 6.75 3015.7 - 765770 - - - 0.0801 - 1.876 0.228 - 280.3 1 2 0 0.0001 11 0 0 0 5.04E+06 1.17E+07 - - - 2.427 0.9998 221125_WJC_METTL3_EV_vs_WT_F03.17237.17237.2 0.00146 20-Oct K.ALDDMISTLK[136.11]K[136.11].L "sp|P49368|TCPG_HUMAN,tr|E9PM09|E9PM09_HUMAN,tr|Q5SZW8|Q5SZW8_HUMAN,tr|E9PRC8|E9PRC8_HUMAN,tr|B4DUR8|B4DUR8_HUMAN,tr|E9PQ35|E9PQ35_HUMAN,tr|Q5SZX6|Q5SZX6_HUMAN" 7 1249.6923 0.29 32486 17237 2 1249.693602 625.8534 T-complex protein 1 subunit gamma OS=Homo sapiens OX=9606 GN=CCT3 PE=1 SV=4 6 3016 - 3.07E+06 - - - 1.0627 - 2.059 0.443 - 252.3 1 2 0 0.0013 11 0 0 0 8.17E+06 2.82E+07 - - - 4.2664 0.9947 221125_WJC_METTL3_EV_vs_WT_F03.17238.17238.3 0.0212 Oct-40 K.AIYHLEAFVAK[136.11].F sp|P40938|RFC3_HUMAN 1 1268.7009 2.28 32487 17238 3 1268.703372 423.9076 Replication factor C subunit 3 OS=Homo sapiens OX=9606 GN=RFC3 PE=1 SV=2 6.79 3016.1 - 681458 - - - 1.9808 - 1.61 0.244 - 54 1 2 0 0.0025 11 0 0 0 1.70E+07 7.44E+06 - - - 2.6126 1 221125_WJC_METTL3_EV_vs_WT_F03.17239.17239.2 7.71E-09 26-Nov F.ANFESDEVELSYAK.N "sp|Q00839|HNRPU_HUMAN,tr|A0A1W2PQL0|A0A1W2PQL0_HUMAN,tr|A0A1W2PPL4|A0A1W2PPL4_HUMAN,tr|A0A1W2PQ74|A0A1W2PQ74_HUMAN,tr|Q5RI18|Q5RI18_HUMAN,tr|A0A1W2PP35|A0A1W2PP35_HUMAN,tr|A0A1W2PPS1|A0A1W2PPS1_HUMAN,tr|A0A1W2PRZ7|A0A1W2PRZ7_HUMAN,tr|A0A1W2PPH7|A0A1W2PPH7_HUMAN,tr|A0A1W2PP34|A0A1W2PP34_HUMAN,tr|A0A1X7SBS1|A0A1X7SBS1_HUMAN" 11 1600.7257 1.01 32488 17239 2 1600.722479 801.3701 Heterogeneous nuclear ribonucleoprotein U OS=Homo sapiens OX=9606 GN=HNRNPU PE=1 SV=6 4 3016.1 - 7.28E+06 - - - -2.0016 - 2.602 0.621 - 317.7 1 1 0 -0.0032 14 0 0 0 1.84E+08 1.81E+08 - - - 6.0264 0.9995 221125_WJC_METTL3_EV_vs_WT_F03.17240.17240.2 0.012 16-Oct K.SNIDALLSR.L "sp|Q9UKM9|RALY_HUMAN,tr|Q5QPM0|Q5QPM0_HUMAN,tr|Q5QPL9|Q5QPL9_HUMAN" 3 987.5349 1.14 32489 17240 2 987.534148 494.7747 RNA-binding protein Raly OS=Homo sapiens OX=9606 GN=RALY PE=1 SV=1 5.55 3016.2 - 3.43E+06 - - - -0.7706 - 1.992 0.282 - 497.1 1 2 0 -0.0008 9 0 0 0 3.32E+07 2.90E+07 - - - 3.1173 1 221125_WJC_METTL3_EV_vs_WT_F03.17241.17241.2 2.65E-08 23/30 K.IFVGGIKEDTEEYNLR.D "sp|P51991|ROA3_HUMAN,tr|A0A7I2V5D8|A0A7I2V5D8_HUMAN,tr|A0A7I2V2R3|A0A7I2V2R3_HUMAN,tr|A0A7I2V4J6|A0A7I2V4J6_HUMAN,tr|A0A7I2V4G0|A0A7I2V4G0_HUMAN,tr|A0A7I2V402|A0A7I2V402_HUMAN" 6 1881.9472 1.52 32490 17241 2 1881.945249 941.9809 Heterogeneous nuclear ribonucleoprotein A3 OS=Homo sapiens OX=9606 GN=HNRNPA3 PE=1 SV=2 4.41 3016.3 - 2.33E+06 - - - -1.0595 - 3.627 0.648 - 1635.4 1 2 1 -0.002 16 0 0 0 2.34E+07 1.54E+07 - - - 6.9941 1 221125_WJC_METTL3_EV_vs_WT_F03.17243.17243.2 3.30E-09 21/30 K.IFVGGIK[136.11]EDTEEYNLR[166.11].D "sp|P51991|ROA3_HUMAN,tr|A0A7I2V5D8|A0A7I2V5D8_HUMAN,tr|A0A7I2V2R3|A0A7I2V2R3_HUMAN,tr|A0A7I2V4J6|A0A7I2V4J6_HUMAN,tr|A0A7I2V4G0|A0A7I2V4G0_HUMAN,tr|A0A7I2V402|A0A7I2V402_HUMAN" 6 1899.9697 1.52 32492 17243 2 1899.966116 950.9921 Heterogeneous nuclear ribonucleoprotein A3 OS=Homo sapiens OX=9606 GN=HNRNPA3 PE=1 SV=2 4.41 3016.5 - 1.90E+06 - - - -1.8932 - 3.189 0.69 - 1420.1 1 2 1 -0.0036 16 0 0 0 2.34E+07 1.54E+07 - - - 6.9874 0.814 221125_WJC_METTL3_EV_vs_WT_F03.17244.17244.3 1.07 Oct-44 K.QDGLSPKEISC[160.03]R.A sp|A1X283|SPD2B_HUMAN 1 1388.6718 33.76 32493 17244 3 1388.671607 463.8979 SH3 and PX domain-containing protein 2B OS=Homo sapiens OX=9606 GN=SH3PXD2B PE=1 SV=3 6.06 3016.6 - 1.50E+06 - - - -0.1491 - 1.361 0.134 - 118.8 1 2 1 -0.0002 12 0 0 0 1.44E+07 4.26E+05 - - - 0.8882 0.9998 221125_WJC_METTL3_EV_vs_WT_F03.17245.17245.3 0.00266 14/56 R.GALQNIIPASTGAAK[136.11].A "sp|P04406|G3P_HUMAN,tr|E7EUT5|E7EUT5_HUMAN" 2 1418.7973 0.75 32494 17245 3 1418.79401 473.9397 Glyceraldehyde-3-phosphate dehydrogenase OS=Homo sapiens OX=9606 GN=GAPDH PE=1 SV=3 8.75 3016.7 - 1.04E+06 - - - -2.3034 - 2.883 0.368 - 288.2 1 2 0 -0.0033 15 0 0 0 5.38E+07 7.16E+07 - - - 5.4048 1 221125_WJC_METTL3_EV_vs_WT_F03.17246.17246.3 1.76E-06 13/44 K.AVGHPFVIQLGR.L "sp|O14980|XPO1_HUMAN,tr|A0A7I2V488|A0A7I2V488_HUMAN,tr|A0A7I2V461|A0A7I2V461_HUMAN,tr|A0A7I2V2H0|A0A7I2V2H0_HUMAN,tr|A0A7I2V3N0|A0A7I2V3N0_HUMAN,tr|A0A7I2V3W6|A0A7I2V3W6_HUMAN,tr|A0A7I2YQV4|A0A7I2YQV4_HUMAN,tr|A0A7I2V2Y6|A0A7I2V2Y6_HUMAN,tr|A0A7I2V6B9|A0A7I2V6B9_HUMAN,tr|A0A7I2V3P3|A0A7I2V3P3_HUMAN,tr|A0A7I2V2S3|A0A7I2V2S3_HUMAN" 11 1292.7353 0.64 32495 17246 3 1292.734955 431.9191 Exportin-1 OS=Homo sapiens OX=9606 GN=XPO1 PE=1 SV=1 9.8 3016.8 - 787608 - - - -0.2978 - 2.896 0.516 - 329.4 1 2 0 -0.0004 12 0 0 0 1.65E+07 2.57E+07 - - - 7.2402 0.9997 221125_WJC_METTL3_EV_vs_WT_F03.17247.17247.3 0.00855 Nov-44 K.LVIPLVVHSAQK[136.11].V "sp|Q5UIP0|RIF1_HUMAN,tr|H7BZN3|H7BZN3_HUMAN" 2 1310.8166 0.46 32496 17247 3 1310.813136 437.9461 Telomere-associated protein RIF1 OS=Homo sapiens OX=9606 GN=RIF1 PE=1 SV=2 8.76 3017 - 763398 - - - -2.6098 - 2.11 0.397 - 148.7 1 2 0 -0.0034 12 0 0 0 1.90E+06 4.13E+06 - - - 5.0349 0.9999 221125_WJC_METTL3_EV_vs_WT_F03.17252.17252.2 0.000104 24-Dec K.ELENANDLLSATK[136.11].R sp|P12270|TPR_HUMAN 1 1424.7238 5.11 32499 17252 2 1424.721981 713.3692 Nucleoprotein TPR OS=Homo sapiens OX=9606 GN=TPR PE=1 SV=3 4.14 3017.5 - 2.13E+06 - - - -1.3041 - 2.644 0.549 - 450.7 1 2 0 -0.0019 13 0 0 0 8.50E+07 1.66E+07 - - - 5.5907 0.9998 221125_WJC_METTL3_EV_vs_WT_F03.17253.17253.2 0.000921 18-Nov R.DGTGVVEFVR.K "sp|Q07955|SRSF1_HUMAN,tr|J3KTL2|J3KTL2_HUMAN,tr|J3KSR8|J3KSR8_HUMAN" 3 1077.5455 1.18 32500 17253 2 1077.544975 539.78 Serine\arginine-rich splicing factor 1 OS=Homo sapiens OX=9606 GN=SRSF1 PE=1 SV=2 4.37 3017.6 - 4.08E+06 - - - -0.4631 - 2.139 0.425 - 562.3 1 2 0 -0.0005 10 0 0 0 7.27E+07 6.16E+07 - - - 4.3022 1 221125_WJC_METTL3_EV_vs_WT_F03.17254.17254.2 6.24E-11 16/28 R.GENLVSMTVEGPPPK[136.11].D "sp|P63162|RSMN_HUMAN,sp|P14678|RSMB_HUMAN,tr|J3QLE5|J3QLE5_HUMAN" 3 1561.7901 0.68 32501 17254 2 1561.790834 781.9023 Small nuclear ribonucleoprotein-associated protein N OS=Homo sapiens OX=9606 GN=SNRPN PE=1 SV=1 4.53 3017.7 - 2.12E+06 - - - 0.4418 - 2.971 0.617 - 937.6 1 2 0 0.0007 15 0 0 0 1.61E+07 2.37E+07 - - - 6.2751 0.9996 221125_WJC_METTL3_EV_vs_WT_F03.17258.17258.2 3.78E-06 18-Oct R.NYFLEEDNYK.N "sp|Q53GS9|SNUT2_HUMAN,tr|B9A018|B9A018_HUMAN,tr|A0A087X1B2|A0A087X1B2_HUMAN" 3 1333.5826 1.35 32505 17258 2 1333.579365 667.7986 U4\U6.U5 tri-snRNP-associated protein 2 OS=Homo sapiens OX=9606 GN=USP39 PE=1 SV=2 4.14 3018.2 - 1.23E+06 - - - -2.461 - 1.942 0.543 - 270.5 1 2 0 -0.0033 10 0 0 0 1.43E+07 1.06E+07 - - - 4.9032 0.9997 221125_WJC_METTL3_EV_vs_WT_F03.17261.17261.2 0.000358 18-Aug R.NYFLEEDNYK[136.11].N "sp|Q53GS9|SNUT2_HUMAN,tr|B9A018|B9A018_HUMAN,tr|A0A087X1B2|A0A087X1B2_HUMAN" 3 1341.5968 1.28 32508 17261 2 1341.596092 671.8057 U4\U6.U5 tri-snRNP-associated protein 2 OS=Homo sapiens OX=9606 GN=USP39 PE=1 SV=2 4.14 3018.6 - 1.04E+06 - - - -0.5628 - 1.555 0.43 - 191.2 1 2 0 -0.0008 10 0 0 0 1.36E+07 1.06E+07 - - - 3.449 0.9998 221125_WJC_METTL3_EV_vs_WT_F03.17265.17265.2 0.00572 18-Oct K.WTLLQEQGTK.T "sp|P48668|K2C6C_HUMAN,sp|P04259|K2C6B_HUMAN,sp|P13647|K2C5_HUMAN,sp|P02538|K2C6A_HUMAN,tr|F8W0C6|F8W0C6_HUMAN" 5 1202.6295 8133.21 32510 17265 2 1202.628678 602.322 "Keratin, type II cytoskeletal 6C OS=Homo sapiens OX=9606 GN=KRT6C PE=1 SV=3" 6 3019.1 - 8.52E+07 - - - -0.7151 - 1.956 0.443 - 275.5 1 2 0 -0.0009 10 0 0 0 1.10E+10 1.35E+06 - - - 4.1854 0.9998 221125_WJC_METTL3_EV_vs_WT_F03.17266.17266.2 1.21E-06 13/28 R.GALQNIIPASTGAAK[136.11].A "sp|P04406|G3P_HUMAN,tr|E7EUT5|E7EUT5_HUMAN" 2 1418.7973 1.16 32511 17266 2 1418.794468 710.4059 Glyceraldehyde-3-phosphate dehydrogenase OS=Homo sapiens OX=9606 GN=GAPDH PE=1 SV=3 8.75 3019.2 - 1.06E+07 - - - -1.9806 - 2.511 0.57 - 356.4 1 2 0 -0.0028 15 0 0 0 5.77E+08 4.97E+08 - - - 5.5137 0.9984 221125_WJC_METTL3_EV_vs_WT_F03.17267.17267.3 0.0171 Sep-48 R.DVGLADR[166.11]FEEYPK[136.11].L sp|Q9HCE5|MET14_HUMAN 1 1555.7637 0.03 32512 17267 3 1555.761878 519.5952 N6-adenosine-methyltransferase non-catalytic subunit OS=Homo sapiens OX=9606 GN=METTL14 PE=1 SV=2 4.32 3019.2 - 8.78E+06 - - - -1.1988 - 1.422 0.421 - 61.1 1 2 1 -0.0019 13 0 0 0 2.18E+06 8.56E+07 - - - 4.1878 0.9998 221125_WJC_METTL3_EV_vs_WT_F03.17268.17268.2 0.000783 18-Dec R.DGTGVVEFVR[166.11].K "sp|Q07955|SRSF1_HUMAN,tr|J3KTL2|J3KTL2_HUMAN,tr|J3KSR8|J3KSR8_HUMAN" 3 1087.5537 1.18 32513 17268 2 1087.552377 544.7841 Serine\arginine-rich splicing factor 1 OS=Homo sapiens OX=9606 GN=SRSF1 PE=1 SV=2 4.37 3019.3 - 5.71E+06 - - - -1.2569 - 2.411 0.445 - 640.2 1 2 0 -0.0014 10 0 0 0 7.27E+07 6.16E+07 - - - 4.7838 0.9998 221125_WJC_METTL3_EV_vs_WT_F03.17269.17269.2 4.28E-05 22-Sep R.DFTPVC[160.03]TTELGR.A sp|P30041|PRDX6_HUMAN 1 1394.65 0.81 32514 17269 2 1394.649272 698.3323 Peroxiredoxin-6 OS=Homo sapiens OX=9606 GN=PRDX6 PE=1 SV=3 4.37 3019.4 - 2.58E+06 - - - -0.5328 - 2.013 0.495 - 264.1 1 2 0 -0.0007 12 0 0 0 5.73E+07 7.07E+07 - - - 4.5377 0.9997 221125_WJC_METTL3_EV_vs_WT_F03.17270.17270.2 0.0115 20-Nov R.EVQLEELEAAR[166.11].D "sp|P51570|GALK1_HUMAN,tr|K7EII7|K7EII7_HUMAN" 2 1295.6597 2.07 32515 17270 2 1295.659817 648.8371 Galactokinase OS=Homo sapiens OX=9606 GN=GALK1 PE=1 SV=1 4.09 3019.4 - 2.19E+06 - - - 0.1173 - 2.143 0.336 - 516.7 1 2 0 0.0002 11 0 0 0 1.87E+08 9.05E+07 - - - 3.5846 0.9992 221125_WJC_METTL3_EV_vs_WT_F03.17272.17272.2 0.0109 20-Dec K.FASLEFSPGSK.K "sp|Q8N766|EMC1_HUMAN,tr|Q5TG59|Q5TG59_HUMAN" 2 1168.5764 1.02 32517 17272 2 1168.580434 585.2955 ER membrane protein complex subunit 1 OS=Homo sapiens OX=9606 GN=EMC1 PE=1 SV=1 6 3019.7 - 1.85E+06 - - - 3.4178 - 2.139 0.494 - 401.5 1 2 0 0.004 11 0 0 0 3.35E+07 3.28E+07 - - - 4.7453 0.9166 221125_WJC_METTL3_EV_vs_WT_F03.17273.17273.2 0.00552 16-Jul R.AQVQEFC[160.03]DY.G "sp|Q86U44|MTA70_HUMAN,tr|H0YFV6|H0YFV6_HUMAN" 2 1158.4652 - 32518 17273 2 1158.467575 580.2399 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 3.67 3019.8 - 1.85E+06 - - - 2.0717 - 1.33 0.398 - 210.4 1 1 0 0.0024 9 0 0 0 - - - - - 2.8049 0.9997 221125_WJC_METTL3_EV_vs_WT_F03.17274.17274.3 0.0922 13/48 K.IVVELPHSVNSKL.- sp|Q8N4Q0|PTGR3_HUMAN 1 1433.8242 1.08 32519 17274 3 1433.822627 478.9487 Prostaglandin reductase 3 OS=Homo sapiens OX=9606 GN=ZADH2 PE=1 SV=1 6.75 3019.9 - 618858 - - - -1.1075 - 2.12 0.32 - 125.3 1 2 0 -0.0016 13 0 0 0 6.65E+06 6.18E+06 - - - 4.1446 0.9999 221125_WJC_METTL3_EV_vs_WT_F03.17275.17275.2 6.39E-06 28-Sep K.GMDADPYNPVLPTNR.A sp|Q9H6T3|RPAP3_HUMAN 1 1658.7723 6.8 32520 17275 2 1658.771539 830.3934 RNA polymerase II-associated protein 3 OS=Homo sapiens OX=9606 GN=RPAP3 PE=1 SV=2 4.21 3020 - 439537 - - - -0.4322 - 1.89 0.607 - 241.6 1 2 0 -0.0007 15 0 0 0 5.34E+06 7.85E+05 - - - 5.0891 0.9998 221125_WJC_METTL3_EV_vs_WT_F03.17281.17281.2 4.14E-05 22-Sep K.SGVSITIDDPVR.T "sp|Q9UKV3|ACINU_HUMAN,tr|G3V3B0|G3V3B0_HUMAN,tr|S4R3H4|S4R3H4_HUMAN,tr|E7EQT4|E7EQT4_HUMAN" 4 1257.6565 1.86 32524 17281 2 1257.656673 629.8355 Apoptotic chromatin condensation inducer in the nucleus OS=Homo sapiens OX=9606 GN=ACIN1 PE=1 SV=2 4.21 3020.5 - 1.30E+07 - - - 0.1527 - 1.858 0.455 - 254 1 2 0 0.0002 12 0 0 0 8.81E+07 4.74E+07 - - - 4.0316 0.9998 221125_WJC_METTL3_EV_vs_WT_F03.17282.17282.2 0.000338 20-Nov K.FNVWDTAGQEK.F "sp|P62826|RAN_HUMAN,tr|H0YFC6|H0YFC6_HUMAN,tr|B5MDF5|B5MDF5_HUMAN,tr|J3KQE5|J3KQE5_HUMAN,tr|F5H018|F5H018_HUMAN" 5 1293.599 0.9 32525 17282 2 1293.598354 647.8068 GTP-binding nuclear protein Ran OS=Homo sapiens OX=9606 GN=RAN PE=1 SV=3 4.37 3020.6 - 4.68E+06 - - - -0.4731 - 2.118 0.466 - 362.6 1 2 0 -0.0006 11 0 0 0 1.68E+08 1.87E+08 - - - 4.5129 0.9979 221125_WJC_METTL3_EV_vs_WT_F03.17283.17283.3 0.000399 Dec-36 R.WVFKEEGVLR.V "sp|P39656|OST48_HUMAN,tr|A0A0C4DGS1|A0A0C4DGS1_HUMAN" 2 1261.6819 0.93 32526 17283 3 1261.68104 421.5679 Dolichyl-diphosphooligosaccharide--protein glycosyltransferase 48 kDa subunit OS=Homo sapiens OX=9606 GN=DDOST PE=1 SV=4 6.14 3020.6 - 4.33E+06 - - - -0.688 - 2.086 0.286 - 183.9 1 2 1 -0.0009 10 0 0 0 4.27E+07 4.61E+07 - - - 3.8756 0.9996 221125_WJC_METTL3_EV_vs_WT_F03.17284.17284.2 4.91E-06 16-Oct R.DPFSQALSR.C "sp|Q96DF8|ESS2_HUMAN,tr|F8WEF8|F8WEF8_HUMAN" 2 1019.5036 1.74 32527 17284 2 1019.502565 510.7591 Splicing factor ESS-2 homolog OS=Homo sapiens OX=9606 GN=ESS2 PE=1 SV=1 5.84 3020.7 - 3.70E+06 - - - -1.024 - 1.909 0.346 - 397.7 1 2 0 -0.001 9 0 0 0 5.78E+07 3.33E+07 - - - 3.4668 0.997 221125_WJC_METTL3_EV_vs_WT_F03.17285.17285.2 1.50E-06 13/26 R.LGSSSLTNIPEEVR[166.11].E "sp|Q6P3W7|SCYL2_HUMAN,tr|F8VSC5|F8VSC5_HUMAN,tr|A0A0U1RQQ9|A0A0U1RQQ9_HUMAN" 3 1510.7867 1.07 32528 17285 2 1510.780253 756.4006 SCY1-like protein 2 OS=Homo sapiens OX=9606 GN=SCYL2 PE=1 SV=1 4.53 3020.8 - 2.41E+06 - - - -4.2389 - 2.793 0.282 - 450.6 1 2 0 -0.0064 14 0 0 0 1.88E+08 1.76E+08 - - - 3.6993 0.9986 221125_WJC_METTL3_EV_vs_WT_F03.17286.17286.2 1.21E-05 16-Nov R.HDDYLVMLK[136.11].A "sp|Q9Y224|RTRAF_HUMAN,tr|G3V4C6|G3V4C6_HUMAN,tr|H0YJB9|H0YJB9_HUMAN" 3 1140.5729 1.16 32529 17286 2 1140.567687 571.2937 "RNA transcription, translation and transport factor protein OS=Homo sapiens OX=9606 GN=RTRAF PE=1 SV=1" 5.21 3020.9 - 2.01E+06 - - - -4.5539 - 2.355 0.504 - 463.3 1 2 0 -0.0052 9 0 0 0 1.00E+08 8.63E+07 - - - 5.2399 0.9964 221125_WJC_METTL3_EV_vs_WT_F03.17288.17288.3 0.000718 14/48 Q.SIVPALEIANAHR.K "sp|P10809|CH60_HUMAN,tr|A0A7I2V2X6|A0A7I2V2X6_HUMAN,tr|A0A7I2YQK6|A0A7I2YQK6_HUMAN,tr|A0A7I2V599|A0A7I2V599_HUMAN,tr|A0A7I2YQ71|A0A7I2YQ71_HUMAN,tr|A0A7I2V5M1|A0A7I2V5M1_HUMAN,tr|A0A7I2V5K3|A0A7I2V5K3_HUMAN,tr|A0A7I2V369|A0A7I2V369_HUMAN" 8 1389.7728 1.26 32531 17288 3 1389.771073 464.2649 "60 kDa heat shock protein, mitochondrial OS=Homo sapiens OX=9606 GN=HSPD1 PE=1 SV=2" 6.47 3021.1 - 1.73E+06 - - - -1.2772 - 2.56 0.486 - 243.4 1 1 0 -0.0018 13 0 0 0 1.08E+08 8.56E+07 - - - 6.5066 0.9997 221125_WJC_METTL3_EV_vs_WT_F03.17289.17289.2 0.000431 14-Jun K.DNEGSWFR.S "sp|Q9BPW8|NIPS1_HUMAN,tr|H7C2U6|H7C2U6_HUMAN,tr|F8WCR5|F8WCR5_HUMAN" 3 1009.4254 2.04 32532 17289 2 1009.426332 505.72 Protein NipSnap homolog 1 OS=Homo sapiens OX=9606 GN=NIPSNAP1 PE=1 SV=1 4.37 3021.2 - 876372 - - - 0.9639 - 1.546 0.481 - 158.6 1 2 0 0.001 8 0 0 0 1.01E+07 4.93E+06 - - - 3.9073 0.9998 221125_WJC_METTL3_EV_vs_WT_F03.17290.17290.3 0.000439 14/44 R.AGLLQVYIHTQK[136.11].N "sp|Q92979|NEP1_HUMAN,tr|A0A087WVM7|A0A087WVM7_HUMAN,tr|V9GYP5|V9GYP5_HUMAN,tr|A0A087WWQ2|A0A087WWQ2_HUMAN" 4 1377.786 0.76 32533 17290 3 1377.784702 460.2693 Ribosomal RNA small subunit methyltransferase NEP1 OS=Homo sapiens OX=9606 GN=EMG1 PE=1 SV=4 8.64 3021.4 - 866570 - - - -0.9312 - 2.375 0.32 - 312.3 1 2 0 -0.0013 12 0 0 0 2.99E+06 3.94E+06 - - - 4.505 0.9996 221125_WJC_METTL3_EV_vs_WT_F03.17292.17292.3 0.000379 13/40 K.IWTHPGWSPLK.T sp|O43172|PRP4_HUMAN 1 1320.6979 1.38 32535 17292 3 1320.694733 441.2399 U4\U6 small nuclear ribonucleoprotein Prp4 OS=Homo sapiens OX=9606 GN=PRPF4 PE=1 SV=2 8.76 3021.6 - 686806 - - - -2.3919 - 2.552 0.315 - 266.1 1 2 0 -0.0032 11 0 0 0 1.57E+08 1.14E+08 - - - 4.7126 0.9926 221125_WJC_METTL3_EV_vs_WT_F03.17293.17293.2 14.1 12-Jul K.IGIEIIK[136.11].R "sp|P10809|CH60_HUMAN,tr|A0A7I2V2X6|A0A7I2V2X6_HUMAN,tr|A0A7I2YQK6|A0A7I2YQK6_HUMAN,tr|A0A7I2V599|A0A7I2V599_HUMAN" 4 792.52 1.36 32536 17293 2 792.519992 397.2673 "60 kDa heat shock protein, mitochondrial OS=Homo sapiens OX=9606 GN=HSPD1 PE=1 SV=2" 6 3021.7 - 681829 - - - -0.0618 - 1.8 0.025 - 105.4 4 2 0 0 7 0 0 0 1.91E+07 1.41E+07 - - - 0.8191 0.9864 221125_WJC_METTL3_EV_vs_WT_F03.17294.17294.3 0.0468 Oct-36 K.LKDIVSLVPR.L "sp|O95573|ACSL3_HUMAN,tr|A0A7P0TBB1|A0A7P0TBB1_HUMAN,tr|A0A7P0TBL9|A0A7P0TBL9_HUMAN,tr|A0A7P0TB52|A0A7P0TB52_HUMAN,tr|A0A7P0T905|A0A7P0T905_HUMAN,tr|A0A7P0TA76|A0A7P0TA76_HUMAN,tr|F5GWH2|F5GWH2_HUMAN,tr|A0A7P0T8L6|A0A7P0T8L6_HUMAN,tr|H7BYZ7|H7BYZ7_HUMAN" 9 1138.7074 0.66 32537 17294 3 1138.706638 380.5764 Fatty acid CoA ligase Acsl3 OS=Homo sapiens OX=9606 GN=ACSL3 PE=1 SV=3 8.75 3021.9 - 454312 - - - -0.6639 - 1.725 0.218 - 92.5 1 2 1 -0.0008 10 0 0 0 3.76E+06 5.72E+06 - - - 2.5626 0.9999 221125_WJC_METTL3_EV_vs_WT_F03.17296.17296.2 1.50E-05 13/22 R.AITGIQAFTASK[136.11].- sp|Q92947|GCDH_HUMAN 1 1214.675 0.71 32538 17296 2 1214.67397 608.3448 "Glutaryl-CoA dehydrogenase, mitochondrial OS=Homo sapiens OX=9606 GN=GCDH PE=1 SV=1" 8.8 3022.1 - 1.34E+07 - - - -0.8792 - 2.77 0.43 - 514.8 1 2 0 -0.0011 12 0 0 0 8.96E+07 1.27E+08 - - - 4.8974 0.9873 221125_WJC_METTL3_EV_vs_WT_F03.17297.17297.2 0.071 18-Aug K.AISSDMYFGR.Q "sp|Q9NP61|ARFG3_HUMAN,tr|H0Y6A0|H0Y6A0_HUMAN" 2 1145.5175 0.9 32539 17297 2 1145.513553 573.766 ADP-ribosylation factor GTPase-activating protein 3 OS=Homo sapiens OX=9606 GN=ARFGAP3 PE=1 SV=1 5.88 3022.1 - 1.96E+06 - - - -3.484 - 1.28 0.279 - 138.1 1 2 0 -0.004 10 0 0 0 2.22E+07 2.45E+07 - - - 1.7895 0.9998 221125_WJC_METTL3_EV_vs_WT_F03.17298.17298.2 1.64E-05 13/26 R.LGSSSLTNIPEEVR.E "sp|Q6P3W7|SCYL2_HUMAN,tr|F8VSC5|F8VSC5_HUMAN,tr|A0A0U1RQQ9|A0A0U1RQQ9_HUMAN" 3 1500.7784 1.07 32540 17298 2 1500.775735 751.3965 SCY1-like protein 2 OS=Homo sapiens OX=9606 GN=SCYL2 PE=1 SV=1 4.53 3022.2 - 8.23E+06 - - - -1.7671 - 2.811 0.497 - 381.1 1 2 0 -0.0027 14 0 0 0 1.88E+08 1.75E+08 - - - 5.3046 1 221125_WJC_METTL3_EV_vs_WT_F03.17299.17299.2 1.06E-06 16-Dec R.HDDYLVMLK.A "sp|Q9Y224|RTRAF_HUMAN,tr|G3V4C6|G3V4C6_HUMAN,tr|H0YJB9|H0YJB9_HUMAN" 3 1132.5587 1.16 32541 17299 2 1132.555811 567.2866 "RNA transcription, translation and transport factor protein OS=Homo sapiens OX=9606 GN=RTRAF PE=1 SV=1" 5.21 3022.2 - 5.94E+06 - - - -2.5341 - 2.637 0.528 - 544 1 2 0 -0.0029 9 0 0 0 1.00E+08 8.63E+07 - - - 5.7451 0.9826 221125_WJC_METTL3_EV_vs_WT_F03.17300.17300.2 0.000319 24-Oct K.GILGYTEHQVVSS.D "sp|P04406|G3P_HUMAN,tr|E7EUT5|E7EUT5_HUMAN" 2 1388.6936 - 32542 17300 2 1388.694197 695.3541 Glyceraldehyde-3-phosphate dehydrogenase OS=Homo sapiens OX=9606 GN=GAPDH PE=1 SV=3 5.24 3022.3 - 5.91E+06 - - - 0.4335 - 1.823 0.419 - 239.7 1 1 0 0.0006 13 0 0 0 - - - - - 3.6767 0.9987 221125_WJC_METTL3_EV_vs_WT_F03.17301.17301.2 0.000246 16-Sep R.YSVDIPLDK.T "sp|P61353|RL27_HUMAN,tr|K7ELC7|K7ELC7_HUMAN" 2 1048.5441 0.53 32543 17301 2 1048.547875 525.2793 60S ribosomal protein L27 OS=Homo sapiens OX=9606 GN=RPL27 PE=1 SV=2 4.21 3022.3 - 5.04E+06 - - - 3.6222 - 1.782 0.478 - 223.1 1 2 0 0.0038 9 0 0 0 5.84E+07 1.11E+08 - - - 4.2417 0.9987 221125_WJC_METTL3_EV_vs_WT_F03.17302.17302.2 0.172 12-Jun R.MTLDDFR.L "sp|P35527|K1C9_HUMAN,tr|K7EQQ3|K7EQQ3_HUMAN" 2 896.4062 244.54 32544 17302 2 896.404913 449.2104 "Keratin, type I cytoskeletal 9 OS=Homo sapiens OX=9606 GN=KRT9 PE=1 SV=3" 4.21 3022.4 - 5.04E+06 - - - -1.4391 - 1.473 0.299 - 191.1 1 2 0 -0.0013 7 0 0 0 7.39E+07 3.02E+05 - - - 2.4762 0.9999 221125_WJC_METTL3_EV_vs_WT_F03.17303.17303.3 0.00295 14/44 R.VLTQLLLNSDHR.S sp|Q5SWX8|ODR4_HUMAN 1 1407.7834 1.69 32545 17303 3 1407.781151 470.2684 Protein odr-4 homolog OS=Homo sapiens OX=9606 GN=ODR4 PE=1 SV=1 6.71 3022.4 - 3.26E+06 - - - -1.6068 - 2.362 0.464 - 306.2 1 2 0 -0.0023 12 0 0 0 9.23E+07 5.48E+07 - - - 6.0949 0.9999 221125_WJC_METTL3_EV_vs_WT_F03.17305.17305.3 0.000529 13/48 K.IVHAFDMEDLGDK.A sp|Q9NZ45|CISD1_HUMAN 1 1488.6919 1.58 32547 17305 3 1488.688852 497.2379 CDGSH iron-sulfur domain-containing protein 1 OS=Homo sapiens OX=9606 GN=CISD1 PE=1 SV=1 4.22 3022.5 - 1.84E+06 - - - -2.034 - 2.571 0.463 - 241.3 1 2 0 -0.003 13 0 0 0 2.68E+07 1.70E+07 - - - 6.2614 0.9999 221125_WJC_METTL3_EV_vs_WT_F03.17306.17306.3 0.000654 Nov-40 K.IWTHPGWSPLK[136.11].T sp|O43172|PRP4_HUMAN 1 1328.7121 1.38 32548 17306 3 1328.710583 443.9113 U4\U6 small nuclear ribonucleoprotein Prp4 OS=Homo sapiens OX=9606 GN=PRPF4 PE=1 SV=2 8.76 3022.6 - 1.37E+06 - - - -1.1357 - 2.27 0.37 - 167.5 1 2 0 -0.0015 11 0 0 0 1.57E+08 1.14E+08 - - - 4.9936 0.9996 221125_WJC_METTL3_EV_vs_WT_F03.17308.17308.3 0.00139 Nov-40 R.FVFDR[166.11]PLPVSR[166.11].L "sp|P25786|PSA1_HUMAN,tr|F5GX11|F5GX11_HUMAN,tr|B4DEV8|B4DEV8_HUMAN" 3 1351.7515 0.98 32550 17308 3 1351.75326 451.5911 Proteasome subunit alpha type-1 OS=Homo sapiens OX=9606 GN=PSMA1 PE=1 SV=1 9.6 3022.8 - 1.13E+06 - - - 1.268 - 1.751 0.359 - 122.6 1 2 0 0.0017 11 0 0 0 6.91E+07 7.05E+07 - - - 4.1334 0.9127 221125_WJC_METTL3_EV_vs_WT_F03.17309.17309.3 0.00388 Oct-40 M.PK[136.11]PGVFDLINK[136.11].A "sp|O75521|ECI2_HUMAN,tr|F1LLU7|F1LLU7_HUMAN,tr|F8W6J1|F8W6J1_HUMAN,tr|C9JB63|C9JB63_HUMAN,tr|F8WAW4|F8WAW4_HUMAN,tr|A0A0C4DGA2|A0A0C4DGA2_HUMAN" 6 1242.7307 1.72 32551 17309 3 1242.729231 415.2508 Enoyl-CoA delta isomerase 2 OS=Homo sapiens OX=9606 GN=ECI2 PE=1 SV=4 9.01 3022.9 - 1.07E+06 - - - -1.1893 - 1.665 0.31 - 94.5 1 1 0 -0.0015 11 0 0 0 1.58E+07 9.20E+06 - - - 3.4441 0.9997 221125_WJC_METTL3_EV_vs_WT_F03.17312.17312.3 0.0231 Sep-32 R.HDDYLVMLK[136.11].A "sp|Q9Y224|RTRAF_HUMAN,tr|G3V4C6|G3V4C6_HUMAN,tr|H0YJB9|H0YJB9_HUMAN" 3 1140.5729 0.001 32554 17312 3 1140.572078 381.1982 "RNA transcription, translation and transport factor protein OS=Homo sapiens OX=9606 GN=RTRAF PE=1 SV=1" 5.21 3023.3 - 905625 - - - -0.704 - 1.853 0.344 - 119.1 1 2 0 -0.0008 9 0 0 0 0.00E+00 1.28E+07 - - - 4.234 0.9853 221125_WJC_METTL3_EV_vs_WT_F03.17313.17313.3 7.21E-05 16/56 R.LTIIVSDPSHC[160.03]NVLR.A "sp|P78346|RPP30_HUMAN,tr|Q5VU11|Q5VU11_HUMAN,tr|Q5VU10|Q5VU10_HUMAN" 3 1722.9087 5.85 32555 17313 3 1722.893184 575.3102 Ribonuclease P protein subunit p30 OS=Homo sapiens OX=9606 GN=RPP30 PE=1 SV=1 6.74 3023.4 - 791245 - - - -8.9999 - 2.146 0.411 - 201.4 1 2 0 -0.0155 15 0 0 0 7.72E+06 1.32E+06 - - - 5.1105 1 221125_WJC_METTL3_EV_vs_WT_F03.17315.17315.2 4.74E-07 13/24 K.NLNNSNLFSPVNR.D "sp|P52948|NUP98_HUMAN,tr|A0A3B3ITD8|A0A3B3ITD8_HUMAN,tr|H0YEN4|H0YEN4_HUMAN" 3 1487.7481 2.08 32556 17315 2 1487.745716 744.8813 Nuclear pore complex protein Nup98-Nup96 OS=Homo sapiens OX=9606 GN=NUP98 PE=1 SV=4 9.75 3023.6 - 8.53E+06 - - - -1.5957 - 2.757 0.626 - 726.7 1 2 0 -0.0024 13 0 0 0 2.27E+08 1.09E+08 - - - 6.2667 0.9998 221125_WJC_METTL3_EV_vs_WT_F03.17317.17317.2 3.57E-06 22-Dec K.IIETLTQQLQAK.G sp|Q9UHV9|PFD2_HUMAN 1 1384.7926 0.8 32557 17317 2 1384.790755 693.4036 Prefoldin subunit 2 OS=Homo sapiens OX=9606 GN=PFDN2 PE=1 SV=1 6 3023.8 - 4.20E+06 - - - -1.3179 - 2.563 0.432 - 413.8 1 2 0 -0.0018 12 0 0 0 6.89E+07 8.63E+07 - - - 4.7076 0.9998 221125_WJC_METTL3_EV_vs_WT_F03.17319.17319.2 1.71E-05 22-Dec K.IIETLTQQLQAK[136.11].G sp|Q9UHV9|PFD2_HUMAN 1 1392.8068 0.8 32559 17319 2 1392.805313 697.4107 Prefoldin subunit 2 OS=Homo sapiens OX=9606 GN=PFDN2 PE=1 SV=1 6 3023.9 - 4.96E+06 - - - -1.0533 - 2.234 0.441 - 362.6 1 2 0 -0.0015 12 0 0 0 6.89E+07 8.63E+07 - - - 4.4127 0.9994 221125_WJC_METTL3_EV_vs_WT_F03.17321.17321.2 0.0049 18-Oct K.DLSQLQENLK[136.11].L sp|Q8IX12|CCAR1_HUMAN 1 1194.6336 3.7 32561 17321 2 1194.634537 598.3241 Cell division cycle and apoptosis regulator protein 1 OS=Homo sapiens OX=9606 GN=CCAR1 PE=1 SV=2 4.37 3024.1 - 3.26E+06 - - - 0.812 - 1.873 0.305 - 242 1 2 0 0.001 10 0 0 0 1.82E+08 4.93E+07 - - - 3.0451 0.9979 221125_WJC_METTL3_EV_vs_WT_F03.17322.17322.2 3.74E-07 20-Oct R.EPATINYPFEK.G "sp|O00217|NDUS8_HUMAN,tr|E9PPW7|E9PPW7_HUMAN,tr|F8W9K7|F8W9K7_HUMAN,tr|H0YDT4|H0YDT4_HUMAN,tr|E9PKH6|E9PKH6_HUMAN,tr|E9PN51|E9PN51_HUMAN" 6 1307.6398 0.95 32562 17322 2 1307.633252 654.8272 "NADH dehydrogenase [ubiquinone] iron-sulfur protein 8, mitochondrial OS=Homo sapiens OX=9606 GN=NDUFS8 PE=1 SV=1" 4.53 3024.2 - 2.39E+06 - - - -4.983 - 2.137 0.537 - 396.7 1 2 0 -0.0065 11 0 0 0 3.33E+07 3.52E+07 - - - 5.0596 0.9999 221125_WJC_METTL3_EV_vs_WT_F03.17323.17323.2 1.87E-05 18-Dec K.QNLLSVGDYR.H sp|O60264|SMCA5_HUMAN 1 1163.5935 0.76 32563 17323 2 1163.592899 582.804 SWI\SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A member 5 OS=Homo sapiens OX=9606 GN=SMARCA5 PE=1 SV=1 5.84 3024.3 - 1.88E+06 - - - -0.5053 - 2.394 0.486 - 561.4 1 2 0 -0.0006 10 0 0 0 2.49E+07 3.28E+07 - - - 5.0671 0.9995 221125_WJC_METTL3_EV_vs_WT_F03.17324.17324.2 0.0854 16-Oct R.VLQALEGLK[136.11].M "sp|P39019|RS19_HUMAN,tr|A0A075B6E2|A0A075B6E2_HUMAN" 2 977.6001 1.25 32564 17324 2 977.598766 489.8073 40S ribosomal protein S19 OS=Homo sapiens OX=9606 GN=RPS19 PE=1 SV=2 5.97 3024.4 - 1.60E+06 - - - -1.3462 - 1.899 0.331 - 268.1 1 2 0 -0.0013 9 0 0 0 2.53E+07 2.02E+07 - - - 3.3407 1 221125_WJC_METTL3_EV_vs_WT_F03.17326.17326.3 2.28E-05 17/44 K.LLGHEVEDVIIK.C sp|Q92900|RENT1_HUMAN 1 1363.7711 1.06 32566 17326 3 1363.771388 455.5976 Regulator of nonsense transcripts 1 OS=Homo sapiens OX=9606 GN=UPF1 PE=1 SV=2 4.65 3024.6 - 1.02E+06 - - - 0.1987 - 3.343 0.448 - 482.8 1 2 0 0.0003 12 0 0 0 2.98E+07 2.80E+07 - - - 6.8799 0.9988 221125_WJC_METTL3_EV_vs_WT_F03.17332.17332.2 0.0789 16-Aug R.DETEFYLGK.R "sp|P18077|RL35A_HUMAN,tr|F8WB72|F8WB72_HUMAN,tr|C9K025|C9K025_HUMAN,tr|F8WBS5|F8WBS5_HUMAN" 4 1100.5026 0.84 32570 17332 2 1100.500595 551.2586 60S ribosomal protein L35a OS=Homo sapiens OX=9606 GN=RPL35A PE=1 SV=2 4.14 3025.3 - 4.19E+06 - - - -1.8273 - 1.655 0.312 - 254.5 1 2 0 -0.002 9 0 0 0 9.44E+07 1.12E+08 - - - 2.8023 0.9999 221125_WJC_METTL3_EV_vs_WT_F03.17333.17333.3 8.11E-05 17/48 R.LGELLGHPSFQVK[136.11].E "sp|Q9BVI4|NOC4L_HUMAN,tr|F5H303|F5H303_HUMAN" 2 1431.7966 0.73 32571 17333 3 1431.793279 478.2728 Nucleolar complex protein 4 homolog OS=Homo sapiens OX=9606 GN=NOC4L PE=1 SV=1 6.75 3025.3 - 3.29E+06 - - - -2.2845 - 3.298 0.456 - 478.2 1 2 0 -0.0033 13 0 0 0 2.09E+07 2.87E+07 - - - 6.8585 0.9998 221125_WJC_METTL3_EV_vs_WT_F03.17334.17334.2 9.38E-06 18-Nov K.QNLLSVGDYR[166.11].H sp|O60264|SMCA5_HUMAN 1 1173.6018 0.76 32572 17334 2 1173.602836 587.8082 SWI\SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A member 5 OS=Homo sapiens OX=9606 GN=SMARCA5 PE=1 SV=1 5.84 3025.4 - 3.06E+06 - - - 0.9194 - 2.452 0.378 - 473.9 1 2 0 0.0011 10 0 0 0 2.49E+07 3.28E+07 - - - 4.3361 1 221125_WJC_METTL3_EV_vs_WT_F03.17335.17335.2 1.10E-08 20/30 K.TVEEAENIAVTSGVVR.K sp|O76070|SYUG_HUMAN 1 1672.8632 0.32 32573 17335 2 1672.862558 837.4389 Gamma-synuclein OS=Homo sapiens OX=9606 GN=SNCG PE=1 SV=2 4.25 3025.5 - 2.31E+06 - - - -0.3712 - 3.714 0.546 - 1237.3 1 2 0 -0.0006 16 0 0 0 3.11E+07 9.72E+07 - - - 6.2994 0.9998 221125_WJC_METTL3_EV_vs_WT_F03.17336.17336.2 0.000619 18-Oct R.GFNLPYQDAR.K "sp|Q8NE71|ABCF1_HUMAN,tr|A0A0G2JIC2|A0A0G2JIC2_HUMAN,tr|Q5STZ8|Q5STZ8_HUMAN,tr|H0YGW7|H0YGW7_HUMAN" 4 1179.5673 0.94 32574 17336 2 1179.566343 590.7909 ATP-binding cassette sub-family F member 1 OS=Homo sapiens OX=9606 GN=ABCF1 PE=1 SV=2 5.84 3025.7 - 1.93E+06 - - - -0.7876 - 2.24 0.451 - 352.7 1 2 0 -0.0009 10 0 0 0 3.79E+07 4.04E+07 - - - 4.6229 0.9999 221125_WJC_METTL3_EV_vs_WT_F03.17337.17337.3 3.59E-06 Nov-48 K.IVHAFDMEDLGDK[136.11].A sp|Q9NZ45|CISD1_HUMAN 1 1496.7061 1.57 32575 17337 3 1496.701875 499.9093 CDGSH iron-sulfur domain-containing protein 1 OS=Homo sapiens OX=9606 GN=CISD1 PE=1 SV=1 4.22 3025.7 - 1.93E+06 - - - -2.8095 - 2.318 0.481 - 254 1 2 0 -0.0042 13 0 0 0 2.68E+07 1.71E+07 - - - 6.1809 1 221125_WJC_METTL3_EV_vs_WT_F03.17338.17338.3 4.00E-06 16/44 K.LLGHEVEDVIIK[136.11].C sp|Q92900|RENT1_HUMAN 1 1371.7853 1.06 32576 17338 3 1371.784247 458.269 Regulator of nonsense transcripts 1 OS=Homo sapiens OX=9606 GN=UPF1 PE=1 SV=2 4.65 3025.8 - 1.57E+06 - - - -0.78 - 2.771 0.456 - 390 1 2 0 -0.0011 12 0 0 0 2.98E+07 2.80E+07 - - - 6.4487 1 221125_WJC_METTL3_EV_vs_WT_F03.17345.17345.3 2.59E-09 23/72 R.FLGTEPEPDAVGLDSGHIR.G sp|Q16762|THTR_HUMAN 1 2008.9854 1.82 32581 17345 3 2008.981363 670.6691 Thiosulfate sulfurtransferase OS=Homo sapiens OX=9606 GN=TST PE=1 SV=4 4.31 3026.7 - 2.43E+06 - - - -2.0194 - 3.353 0.593 - 365 1 2 0 -0.0041 19 0 0 0 4.47E+07 2.46E+07 - - - 8.1226 0.9938 221125_WJC_METTL3_EV_vs_WT_F03.17346.17346.2 9.38 12-Oct K.IGIEIIK.R "sp|P10809|CH60_HUMAN,tr|A0A7I2V2X6|A0A7I2V2X6_HUMAN,tr|A0A7I2YQK6|A0A7I2YQK6_HUMAN,tr|A0A7I2V599|A0A7I2V599_HUMAN" 4 784.5058 1.36 32582 17346 2 784.504237 393.2602 "60 kDa heat shock protein, mitochondrial OS=Homo sapiens OX=9606 GN=HSPD1 PE=1 SV=2" 6 3026.8 - 2.26E+06 - - - -2.0446 - 2.031 0.034 - 243.7 1 2 0 -0.0016 7 0 0 0 1.91E+07 1.41E+07 - - - 1.5366 0.9996 221125_WJC_METTL3_EV_vs_WT_F03.17347.17347.2 0.00389 14-Sep R.FDLQQLQR[166.11].E "sp|Q13948|CASP_HUMAN,tr|A0A2R8Y852|A0A2R8Y852_HUMAN,tr|A0A2R8YDI1|A0A2R8YDI1_HUMAN" 3 1056.5592 0.54 32583 17347 2 1056.558363 529.2869 Protein CASP OS=Homo sapiens OX=9606 GN=CUX1 PE=1 SV=2 5.84 3026.9 - 5.63E+06 - - - -0.7572 - 1.825 0.327 - 348.3 1 2 0 -0.0008 8 0 0 0 6.03E+07 1.11E+08 - - - 3.2703 1 221125_WJC_METTL3_EV_vs_WT_F03.17349.17349.2 4.23E-08 16/24 K.QVAEAYEVLSDAK[136.11].K "sp|O75190|DNJB6_HUMAN,sp|Q8WWF6|DNJB3_HUMAN,tr|C9JDX6|C9JDX6_HUMAN,tr|E9PH18|E9PH18_HUMAN,tr|A0A0J9YX62|A0A0J9YX62_HUMAN,tr|C9JB42|C9JB42_HUMAN,tr|C9JDR7|C9JDR7_HUMAN,tr|C9J2P2|C9J2P2_HUMAN,tr|C9J2C4|C9J2C4_HUMAN,tr|F8WCZ4|F8WCZ4_HUMAN" 10 1429.718 1.54 32585 17349 2 1429.717505 715.8663 DnaJ homolog subfamily B member 6 OS=Homo sapiens OX=9606 GN=DNAJB6 PE=1 SV=2 4.14 3027.1 - 1.07E+06 - - - -0.3637 - 2.908 0.595 - 853.2 1 2 0 -0.0005 13 0 0 0 5.35E+07 3.48E+07 - - - 6.1752 0.9999 221125_WJC_METTL3_EV_vs_WT_F03.17350.17350.2 0.00867 15/26 R.DVVIC[160.03]PDASLEDAK.K "sp|Q99497|PARK7_HUMAN,tr|K7EN27|K7EN27_HUMAN,tr|K7ELW0|K7ELW0_HUMAN" 3 1530.7236 1.38 32586 17350 2 1530.722755 766.3691 Parkinson disease protein 7 OS=Homo sapiens OX=9606 GN=PARK7 PE=1 SV=2 3.84 3027.2 - 946234 - - - -0.535 - 2.838 0.488 - 732 1 2 0 -0.0008 14 0 0 0 4.86E+07 3.52E+07 - - - 5.2627 0.9998 221125_WJC_METTL3_EV_vs_WT_F03.17351.17351.2 7.75E-05 16/22 K.LLGHEVEDVIIK.C sp|Q92900|RENT1_HUMAN 1 1363.7711 2.3 32587 17351 2 1363.770843 682.8928 Regulator of nonsense transcripts 1 OS=Homo sapiens OX=9606 GN=UPF1 PE=1 SV=2 4.65 3027.3 - 837369 - - - -0.2009 - 2.965 0.274 - 1068.3 1 2 0 -0.0003 12 0 0 0 1.27E+07 5.53E+06 - - - 3.9244 0.821 221125_WJC_METTL3_EV_vs_WT_F03.17352.17352.2 0.000103 14/22 Q.ISNLEAQITDVR.Q "sp|P35527|K1C9_HUMAN,tr|K7EQQ3|K7EQQ3_HUMAN" 2 1357.7201 2.91 32588 17352 2 1357.71245 679.8673 "Keratin, type I cytoskeletal 9 OS=Homo sapiens OX=9606 GN=KRT9 PE=1 SV=3" 4.37 3027.5 - 785072 - - - -5.6669 - 2.9 0.415 - 905.9 1 1 0 -0.0077 12 0 0 0 2.03E+07 6.97E+06 - - - 4.9052 1 221125_WJC_METTL3_EV_vs_WT_F03.17353.17353.3 2.16E-05 18/40 K.QEVAVFVFDKK.L "sp|Q6P3W7|SCYL2_HUMAN,tr|F8VSC5|F8VSC5_HUMAN,tr|A0A0U1RQQ9|A0A0U1RQQ9_HUMAN" 3 1308.7078 1.28 32589 17353 3 1308.708631 437.2432 SCY1-like protein 2 OS=Homo sapiens OX=9606 GN=SCYL2 PE=1 SV=1 6.07 3027.6 - 766962 - - - 0.6441 - 2.602 0.503 - 393.2 1 2 0 0.0008 11 0 0 0 5.53E+07 4.33E+07 - - - 6.8643 0.9977 221125_WJC_METTL3_EV_vs_WT_F03.17354.17354.2 0.0412 22-Aug R.ESFNPESYELDK[136.11].S "sp|P49903|SPS1_HUMAN,tr|Q5T5U6|Q5T5U6_HUMAN" 2 1464.65 0.001 32590 17354 2 1464.64666 733.3323 "Selenide, water dikinase 1 OS=Homo sapiens OX=9606 GN=SEPHS1 PE=1 SV=2" 4 3027.7 - 503047 - - - -2.2838 - 1.441 0.34 - 134.6 1 2 0 -0.0033 12 0 0 0 0.00E+00 5.01E+06 - - - 2.5125 0.9859 221125_WJC_METTL3_EV_vs_WT_F03.17355.17355.3 0.131 Sep-40 R.EVQLEELEAAR.D "sp|P51570|GALK1_HUMAN,tr|K7EII7|K7EII7_HUMAN" 2 1285.6514 1.36 32591 17355 3 1285.65359 429.5577 Galactokinase OS=Homo sapiens OX=9606 GN=GALK1 PE=1 SV=1 4.09 3027.9 - 418888 - - - 1.7073 - 1.668 0.17 - 141.6 1 2 0 0.0022 11 0 0 0 4.56E+06 3.37E+06 - - - 1.8882 0.9998 221125_WJC_METTL3_EV_vs_WT_F03.17357.17357.2 6.15E-05 20-Dec R.EVQLEELEAAR.D "sp|P51570|GALK1_HUMAN,tr|K7EII7|K7EII7_HUMAN" 2 1285.6514 2.07 32592 17357 2 1285.649898 643.833 Galactokinase OS=Homo sapiens OX=9606 GN=GALK1 PE=1 SV=1 4.09 3028.1 - 7.05E+06 - - - -1.1644 - 2.404 0.456 - 723.8 1 2 0 -0.0015 11 0 0 0 1.87E+08 9.05E+07 - - - 4.7814 1 221125_WJC_METTL3_EV_vs_WT_F03.17359.17359.3 4.64E-13 22/80 R.VTGEADVEFATHEDAVAAMSK.D "sp|P31943|HNRH1_HUMAN,tr|H0YBD7|H0YBD7_HUMAN,tr|H0YB39|H0YB39_HUMAN,tr|H0YBG7|H0YBG7_HUMAN,tr|E9PCY7|E9PCY7_HUMAN,tr|G8JLB6|G8JLB6_HUMAN" 6 2176.9947 1.22 32593 17359 3 2176.993253 726.6722 Heterogeneous nuclear ribonucleoprotein H OS=Homo sapiens OX=9606 GN=HNRNPH1 PE=1 SV=4 4.17 3028.3 - 1.08E+07 - - - -0.6481 - 4.345 0.695 - 494.5 1 2 0 -0.0014 21 0 0 0 1.73E+08 1.41E+08 - - - 9.8101 0.9936 221125_WJC_METTL3_EV_vs_WT_F03.17360.17360.2 0.0591 24-Sep K.QVAEAYEVLSDAK.K "sp|O75190|DNJB6_HUMAN,sp|Q8WWF6|DNJB3_HUMAN,tr|C9JDX6|C9JDX6_HUMAN,tr|E9PH18|E9PH18_HUMAN,tr|A0A0J9YX62|A0A0J9YX62_HUMAN,tr|C9JB42|C9JB42_HUMAN,tr|C9JDR7|C9JDR7_HUMAN,tr|C9J2P2|C9J2P2_HUMAN,tr|C9J2C4|C9J2C4_HUMAN,tr|F8WCZ4|F8WCZ4_HUMAN" 10 1421.7038 1.54 32594 17360 2 1421.70795 711.8592 DnaJ homolog subfamily B member 6 OS=Homo sapiens OX=9606 GN=DNAJB6 PE=1 SV=2 4.14 3028.3 - 1.68E+07 - - - 2.9014 - 1.521 0.259 - 121.5 1 2 0 0.0041 13 0 0 0 5.39E+07 3.50E+07 - - - 2.029 0.998 221125_WJC_METTL3_EV_vs_WT_F03.17362.17362.2 6.22E-06 20-Nov K.SANVNEFPVLK.A sp|P55060|XPO2_HUMAN 1 1216.6452 0.62 32596 17362 2 1216.639775 609.3299 Exportin-2 OS=Homo sapiens OX=9606 GN=CSE1L PE=1 SV=3 5.72 3028.5 - 2.00E+06 - - - -4.4491 - 2.359 0.413 - 502.8 1 2 0 -0.0054 11 0 0 0 5.92E+07 9.48E+07 - - - 4.4115 1 221125_WJC_METTL3_EV_vs_WT_F03.17363.17363.3 7.35E-09 27/72 R.FLGTEPEPDAVGLDSGHIR[166.11].G sp|Q16762|THTR_HUMAN 1 2018.9937 1.82 32597 17363 3 2018.99335 674.0052 Thiosulfate sulfurtransferase OS=Homo sapiens OX=9606 GN=TST PE=1 SV=4 4.31 3028.6 - 1.50E+06 - - - -0.1684 - 3.249 0.587 - 337.1 1 2 0 -0.0003 19 0 0 0 4.47E+07 2.46E+07 - - - 7.9793 0.9998 221125_WJC_METTL3_EV_vs_WT_F03.17364.17364.3 0.0107 Oct-40 R.MSVEADINGLR.R "sp|P02533|K1C14_HUMAN,sp|P08727|K1C19_HUMAN,tr|C9JM50|C9JM50_HUMAN,tr|K7EMS3|K7EMS3_HUMAN" 4 1203.5918 47.79 32598 17364 3 1203.590883 402.2045 "Keratin, type I cytoskeletal 14 OS=Homo sapiens OX=9606 GN=KRT14 PE=1 SV=4" 4.37 3028.6 - 1.45E+06 - - - -0.7386 - 2.163 0.335 - 92.8 1 2 0 -0.0009 11 0 0 0 1.77E+07 3.70E+05 - - - 4.4664 0.8911 221125_WJC_METTL3_EV_vs_WT_F03.17368.17368.2 0.00273 20-Sep R.EQDLPLAEAVR[166.11].P sp|Q96A49|SYAP1_HUMAN 1 1249.6542 1.83 32600 17368 2 1249.657717 625.8344 Synapse-associated protein 1 OS=Homo sapiens OX=9606 GN=SYAP1 PE=1 SV=1 4.14 3029.2 - 1.56E+06 - - - 2.8256 - 1.843 0.315 - 220 1 1 0 0.0035 11 0 0 0 6.90E+07 3.76E+07 - - - 3.0204 0.9998 221125_WJC_METTL3_EV_vs_WT_F03.17369.17369.2 9.12E-05 18-Dec K.QDSLVINLNR.S sp|Q9Y5B9|SP16H_HUMAN 1 1170.6357 1.01 32601 17369 2 1170.637073 586.3251 FACT complex subunit SPT16 OS=Homo sapiens OX=9606 GN=SUPT16H PE=1 SV=1 5.84 3029.3 - 1.96E+06 - - - 1.1848 - 2.354 0.483 - 551.5 1 2 0 0.0014 10 0 0 0 3.38E+07 3.36E+07 - - - 4.9977 0.9998 221125_WJC_METTL3_EV_vs_WT_F03.17371.17371.2 8.97E-06 14/18 K.QDSLVINLNR[166.11].S sp|Q9Y5B9|SP16H_HUMAN 1 1180.644 1.01 32603 17371 2 1180.644496 591.3293 FACT complex subunit SPT16 OS=Homo sapiens OX=9606 GN=SUPT16H PE=1 SV=1 5.84 3029.4 - 2.46E+06 - - - 0.4574 - 2.11 0.409 - 788.7 1 2 0 0.0005 10 0 0 0 3.38E+07 3.36E+07 - - - 4.1459 0.9568 221125_WJC_METTL3_EV_vs_WT_F03.17372.17372.2 0.14 20-Sep K.K[136.11]ISSIQSIVPA.L "sp|P10809|CH60_HUMAN,tr|A0A7I2V2X6|A0A7I2V2X6_HUMAN,tr|A0A7I2YQK6|A0A7I2YQK6_HUMAN,tr|A0A7I2V599|A0A7I2V599_HUMAN,tr|A0A7I2YQ71|A0A7I2YQ71_HUMAN,tr|A0A7I2V5M1|A0A7I2V5M1_HUMAN,tr|A0A7I2V5K3|A0A7I2V5K3_HUMAN,tr|A0A7I2V369|A0A7I2V369_HUMAN" 8 1149.6849 1.22 32604 17372 2 1149.684131 575.8497 "60 kDa heat shock protein, mitochondrial OS=Homo sapiens OX=9606 GN=HSPD1 PE=1 SV=2" 8.75 3029.6 - 1.79E+06 - - - -0.6463 - 1.845 0.269 - 164.2 1 1 0 -0.0007 11 0 0 0 4.50E+07 3.69E+07 - - - 2.6845 0.9954 221125_WJC_METTL3_EV_vs_WT_F03.17373.17373.3 0.0203 Nov-32 K.LNIPWNHIR[166.11].L "sp|Q9NRN7|ADPPT_HUMAN,tr|E9PNF3|E9PNF3_HUMAN,tr|E9PLW6|E9PLW6_HUMAN" 3 1171.649 0.33 32605 17373 3 1171.64767 391.5569 L-aminoadipate-semialdehyde dehydrogenase-phosphopantetheinyl transferase OS=Homo sapiens OX=9606 GN=AASDHPPT PE=1 SV=2 9.76 3029.7 - 892921 - - - -1.1189 - 1.866 0.17 - 164 1 2 0 -0.0013 9 0 0 0 4.45E+06 1.33E+07 - - - 2.315 0.9999 221125_WJC_METTL3_EV_vs_WT_F03.17374.17374.3 0.00406 Dec-36 R.HNNLDLVIIR[166.11].E "sp|O43837|IDH3B_HUMAN,tr|A0A087WZN1|A0A087WZN1_HUMAN,tr|A0A087X2E5|A0A087X2E5_HUMAN" 3 1215.6963 1.49 32606 17374 3 1215.696035 406.2394 "Isocitrate dehydrogenase [NAD] subunit beta, mitochondrial OS=Homo sapiens OX=9606 GN=IDH3B PE=1 SV=2" 6.74 3029.8 - 634296 - - - -0.2394 - 2.36 0.398 - 203.2 1 2 0 -0.0003 10 0 0 0 1.14E+07 7.65E+06 - - - 5.4849 0.9788 221125_WJC_METTL3_EV_vs_WT_F03.17376.17376.2 0.000481 Aug-36 R.HLLPNSGAAATSAAMAAAA.A sp|Q9BQ04|RBM4B_HUMAN 1 1694.841 - 32608 17376 2 1694.840318 848.4278 RNA-binding protein 4B OS=Homo sapiens OX=9606 GN=RBM4B PE=1 SV=1 6.74 3030.1 - 580000 - - - -0.4048 - 1.721 0.407 - 87.1 1 1 0 -0.0007 19 0 0 0 - - - - - 3.3816 0.9984 221125_WJC_METTL3_EV_vs_WT_F03.17379.17379.3 1.64E-06 17/48 Q.SIVPALEIANAHR[166.11].K "sp|P10809|CH60_HUMAN,tr|A0A7I2V2X6|A0A7I2V2X6_HUMAN,tr|A0A7I2YQK6|A0A7I2YQK6_HUMAN,tr|A0A7I2V599|A0A7I2V599_HUMAN,tr|A0A7I2YQ71|A0A7I2YQ71_HUMAN,tr|A0A7I2V5M1|A0A7I2V5M1_HUMAN,tr|A0A7I2V5K3|A0A7I2V5K3_HUMAN,tr|A0A7I2V369|A0A7I2V369_HUMAN" 8 1399.7811 1.26 32610 17379 3 1399.780086 467.601 "60 kDa heat shock protein, mitochondrial OS=Homo sapiens OX=9606 GN=HSPD1 PE=1 SV=2" 6.47 3030.4 - 6.19E+06 - - - -0.7373 - 2.92 0.545 - 357.6 1 1 0 -0.001 13 0 0 0 1.08E+08 8.56E+07 - - - 7.5213 0.9885 221125_WJC_METTL3_EV_vs_WT_F03.17380.17380.2 0.000269 20-Oct R.EQDLPLAEAVR.P sp|Q96A49|SYAP1_HUMAN 1 1239.6459 1.72 32611 17380 2 1239.645141 620.8302 Synapse-associated protein 1 OS=Homo sapiens OX=9606 GN=SYAP1 PE=1 SV=1 4.14 3030.5 - 3.29E+06 - - - -0.6252 - 1.943 0.455 - 224.6 1 1 0 -0.0008 11 0 0 0 6.41E+07 3.73E+07 - - - 4.1983 1 221125_WJC_METTL3_EV_vs_WT_F03.17382.17382.3 2.88E-09 21/68 K.MVMIQDGPLPTGADKPLR.L sp|Q96I24|FUBP3_HUMAN 1 1938.0067 1.89 32613 17382 3 1938.007504 647.0095 Far upstream element-binding protein 3 OS=Homo sapiens OX=9606 GN=FUBP3 PE=1 SV=2 5.71 3030.6 - 4.01E+06 - - - 0.4205 - 3.665 0.618 - 485.2 1 2 0 0.0008 18 0 0 0 3.99E+08 2.12E+08 - - - 8.6641 1 221125_WJC_METTL3_EV_vs_WT_F03.17383.17383.3 1.78E-11 22/68 K.MVMIQDGPLPTGADK[136.11]PLR[166.11].L sp|Q96I24|FUBP3_HUMAN 1 1956.0292 1.89 32614 17383 3 1956.028336 653.017 Far upstream element-binding protein 3 OS=Homo sapiens OX=9606 GN=FUBP3 PE=1 SV=2 5.71 3030.6 - 2.84E+06 - - - -0.4208 - 4.215 0.658 - 606 1 2 0 -0.0008 18 0 0 0 3.99E+08 2.12E+08 - - - 9.4582 0.9565 221125_WJC_METTL3_EV_vs_WT_F03.17384.17384.2 0.00336 20-Sep K.KISSIQSIVPA.L "sp|P10809|CH60_HUMAN,tr|A0A7I2V2X6|A0A7I2V2X6_HUMAN,tr|A0A7I2YQK6|A0A7I2YQK6_HUMAN,tr|A0A7I2V599|A0A7I2V599_HUMAN,tr|A0A7I2YQ71|A0A7I2YQ71_HUMAN,tr|A0A7I2V5M1|A0A7I2V5M1_HUMAN,tr|A0A7I2V5K3|A0A7I2V5K3_HUMAN,tr|A0A7I2V369|A0A7I2V369_HUMAN" 8 1141.6707 1.22 32615 17384 2 1141.671313 571.8426 "60 kDa heat shock protein, mitochondrial OS=Homo sapiens OX=9606 GN=HSPD1 PE=1 SV=2" 8.75 3030.7 - 2.63E+06 - - - 0.5597 - 1.819 0.279 - 160.5 1 1 0 0.0006 11 0 0 0 4.50E+07 3.69E+07 - - - 2.72 0.9998 221125_WJC_METTL3_EV_vs_WT_F03.17385.17385.2 1.50E-05 15/22 K.LAQLEAALQQAK.Q sp|Q6KB66|K2C80_HUMAN 1 1282.7245 129.84 32616 17385 2 1282.726008 642.3695 "Keratin, type II cytoskeletal 80 OS=Homo sapiens OX=9606 GN=KRT80 PE=1 SV=2" 6 3030.8 - 2.60E+06 - - - 1.1748 - 2.935 0.33 - 988.1 1 2 0 0.0015 12 0 0 0 2.16E+07 1.66E+05 - - - 4.3109 0.9992 221125_WJC_METTL3_EV_vs_WT_F03.17386.17386.2 0.0145 18-Sep K.GSELEITLTR[166.11].G "sp|P41252|SYIC_HUMAN,tr|A0A804HL54|A0A804HL54_HUMAN,tr|A0A804HJN6|A0A804HJN6_HUMAN,tr|A0A804HHW9|A0A804HHW9_HUMAN,tr|A0A0A0MSX9|A0A0A0MSX9_HUMAN,tr|J3KR24|J3KR24_HUMAN" 6 1127.6062 1.21 32617 17386 2 1127.607723 564.8104 "Isoleucine--tRNA ligase, cytoplasmic OS=Homo sapiens OX=9606 GN=IARS1 PE=1 SV=2" 4.53 3030.9 - 1.65E+06 - - - 1.3746 - 1.981 0.274 - 256.1 1 2 0 0.0015 10 0 0 0 2.00E+07 1.65E+07 - - - 2.9724 0.999 221125_WJC_METTL3_EV_vs_WT_F03.17387.17387.3 0.0015 Nov-52 K.YAATTTPFTPLHIK.V sp|Q9HCM9|TRI39_HUMAN 1 1559.8348 2.18 32618 17387 3 1559.837618 520.9522 E3 ubiquitin-protein ligase TRIM39 OS=Homo sapiens OX=9606 GN=TRIM39 PE=1 SV=2 8.6 3030.9 - 1.58E+06 - - - 1.8194 - 1.923 0.305 - 91.2 1 2 0 0.0028 14 0 0 0 1.45E+07 6.66E+06 - - - 3.6774 0.9946 221125_WJC_METTL3_EV_vs_WT_F03.17388.17388.3 2.33E-08 21/44 K.APIQDIWYHEDR.L "sp|Q9Y3D9|RT23_HUMAN,tr|J3QLR8|J3QLR8_HUMAN" 2 1541.7263 0.73 32619 17388 3 1542.736802 514.916 "28S ribosomal protein S23, mitochondrial OS=Homo sapiens OX=9606 GN=MRPS23 PE=1 SV=2" 4.54 3031 - 1.44E+06 - - - 655.4406 - 3.187 0.544 - 801.7 1 2 0 1.0105 12 0 0 0 2.75E+07 3.76E+07 - - - 7.5379 1 221125_WJC_METTL3_EV_vs_WT_F03.17390.17390.3 8.63E-05 Dec-48 K.GVSIPLMHEAMQK.W "sp|Q6Y7W6|GGYF2_HUMAN,tr|A0A7I2V3H7|A0A7I2V3H7_HUMAN,tr|I1E4Y6|I1E4Y6_HUMAN,tr|A0A7I2V516|A0A7I2V516_HUMAN,tr|A0A7I2V3H0|A0A7I2V3H0_HUMAN,tr|C9JHW1|C9JHW1_HUMAN,tr|A0A7I2V361|A0A7I2V361_HUMAN,tr|E7ESB6|E7ESB6_HUMAN" 8 1439.7265 3.03 32621 17390 3 1439.725227 480.9161 GRB10-interacting GYF protein 2 OS=Homo sapiens OX=9606 GN=GIGYF2 PE=1 SV=1 6.75 3031.3 - 988161 - - - -0.8779 - 2.37 0.472 - 128.8 1 2 0 -0.0013 13 0 0 0 1.42E+07 4.67E+06 - - - 6.1415 0.9995 221125_WJC_METTL3_EV_vs_WT_F03.17391.17391.2 1.30E-07 13/28 K.SSGVPVDGFYTEEVR[166.11].Q "sp|Q9BSD7|NTPCR_HUMAN,tr|Q5TDF0|Q5TDF0_HUMAN" 2 1650.7765 1.08 32622 17391 2 1650.771076 826.3955 Cancer-related nucleoside-triphosphatase OS=Homo sapiens OX=9606 GN=NTPCR PE=1 SV=1 4.14 3031.4 - 756362 - - - -3.2772 - 2.238 0.579 - 504.2 1 2 0 -0.0054 15 0 0 0 9.66E+06 8.95E+06 - - - 5.2964 0.9999 221125_WJC_METTL3_EV_vs_WT_F03.17394.17394.2 2.26E-10 14/26 K.IQMSSMESQNSLLR[166.11].Q "sp|P82094|TMF1_HUMAN,tr|A0A2R8Y7M0|A0A2R8Y7M0_HUMAN" 2 1632.7839 1.43 32625 17394 2 1632.783376 817.3992 TATA element modulatory factor OS=Homo sapiens OX=9606 GN=TMF1 PE=1 SV=2 6 3031.8 - 405366 - - - -0.3191 - 2.897 0.527 - 654.3 1 2 0 -0.0005 14 0 0 0 1.09E+07 7.59E+06 - - - 5.6025 0.9995 221125_WJC_METTL3_EV_vs_WT_F03.17398.17398.2 0.116 14-Jul K.ESILDLSK.Y "sp|Q9UK45|LSM7_HUMAN,tr|K7ENY5|K7ENY5_HUMAN,tr|K7EML7|K7EML7_HUMAN" 3 903.4913 2.13 32627 17398 2 903.490809 452.7529 U6 snRNA-associated Sm-like protein LSm7 OS=Homo sapiens OX=9606 GN=LSM7 PE=1 SV=1 4.37 3032.3 - 6.87E+06 - - - -0.5578 - 1.601 0.36 - 169.8 1 2 0 -0.0005 8 0 0 0 5.34E+07 2.51E+07 - - - 3.1192 0.9998 221125_WJC_METTL3_EV_vs_WT_F03.17399.17399.2 0.000592 16-Sep R.QPTPPFFGR.D sp|Q96PK6|RBM14_HUMAN 1 1045.5345 2.02 32628 17399 2 1045.534559 523.7745 RNA-binding protein 14 OS=Homo sapiens OX=9606 GN=RBM14 PE=1 SV=2 9.75 3032.4 - 5.87E+06 - - - 0.0421 - 1.51 0.497 - 384.4 1 2 0 0 9 0 0 0 9.97E+07 4.94E+07 - - - 3.9041 1 221125_WJC_METTL3_EV_vs_WT_F03.17400.17400.3 0.0019 14/40 K.QEVAVFVFDK[136.11]K[136.11].L "sp|Q6P3W7|SCYL2_HUMAN,tr|F8VSC5|F8VSC5_HUMAN,tr|A0A0U1RQQ9|A0A0U1RQQ9_HUMAN" 3 1324.7362 1.29 32629 17400 3 1324.736277 442.586 SCY1-like protein 2 OS=Homo sapiens OX=9606 GN=SCYL2 PE=1 SV=1 6.07 3032.4 - 4.30E+06 - - - 0.0672 - 2.273 0.495 - 244.5 1 2 0 0.0001 11 0 0 0 5.57E+07 4.32E+07 - - - 6.3913 0.9996 221125_WJC_METTL3_EV_vs_WT_F03.17401.17401.2 0.0178 14-Jul K.ESILDLSK[136.11].Y "sp|Q9UK45|LSM7_HUMAN,tr|K7ENY5|K7ENY5_HUMAN,tr|K7EML7|K7EML7_HUMAN" 3 911.5055 2.13 32630 17401 2 911.50526 456.76 U6 snRNA-associated Sm-like protein LSm7 OS=Homo sapiens OX=9606 GN=LSM7 PE=1 SV=1 4.37 3032.5 - 3.04E+06 - - - -0.2776 - 1.602 0.37 - 137.3 1 2 0 -0.0003 8 0 0 0 5.34E+07 2.51E+07 - - - 3.195 1 221125_WJC_METTL3_EV_vs_WT_F03.17402.17402.2 8.81E-08 13/26 K.IQMSSMESQNSLLR.Q "sp|P82094|TMF1_HUMAN,tr|A0A2R8Y7M0|A0A2R8Y7M0_HUMAN" 2 1622.7756 1.43 32631 17402 2 1622.776681 812.3951 TATA element modulatory factor OS=Homo sapiens OX=9606 GN=TMF1 PE=1 SV=2 6 3032.6 - 1.27E+06 - - - 0.6495 - 2.831 0.607 - 470.4 1 2 0 0.0011 14 0 0 0 1.09E+07 7.59E+06 - - - 6.1354 0.9746 221125_WJC_METTL3_EV_vs_WT_F03.17403.17403.2 0.00076 13/26 F.GTLSPSLGNSSILK[136.11].T sp|P49790|NU153_HUMAN 1 1380.7704 1.35 32632 17403 2 1380.773754 691.3925 Nuclear pore complex protein Nup153 OS=Homo sapiens OX=9606 GN=NUP153 PE=1 SV=2 8.75 3032.8 - 1.27E+06 - - - 2.4327 - 2.681 0.418 - 521.1 1 1 0 0.0034 14 0 0 0 1.96E+07 1.45E+07 - - - 4.6021 0.9989 221125_WJC_METTL3_EV_vs_WT_F03.17404.17404.3 0.000117 13/56 R.REPFLLSGGDDGALK.L sp|Q9BQ67|GRWD1_HUMAN 1 1573.81 1.32 32633 17404 3 1573.815306 525.6106 Glutamate-rich WD repeat-containing protein 1 OS=Homo sapiens OX=9606 GN=GRWD1 PE=1 SV=1 4.56 3032.8 - 2.11E+06 - - - 3.3581 - 2.218 0.345 - 210.2 1 2 0 0.0053 15 0 0 0 5.86E+06 4.44E+06 - - - 4.4636 0.9992 221125_WJC_METTL3_EV_vs_WT_F03.17407.17407.2 2.04E-06 13/24 K.VIGGDDLSTLTGK.N sp|P00492|HPRT_HUMAN 1 1274.6718 0.75 32636 17407 2 1274.667304 638.3432 Hypoxanthine-guanine phosphoribosyltransferase OS=Homo sapiens OX=9606 GN=HPRT1 PE=1 SV=2 4.21 3033.2 - 970908 - - - -3.5248 - 2.428 0.474 - 326.3 1 2 0 -0.0045 13 0 0 0 2.02E+07 2.68E+07 - - - 4.8172 0.9938 221125_WJC_METTL3_EV_vs_WT_F03.17408.17408.2 0.0148 13/18 V.PALEIANAHR.K "sp|P10809|CH60_HUMAN,tr|A0A7I2V2X6|A0A7I2V2X6_HUMAN,tr|A0A7I2YQK6|A0A7I2YQK6_HUMAN,tr|A0A7I2V599|A0A7I2V599_HUMAN,tr|A0A7I2YQ71|A0A7I2YQ71_HUMAN,tr|A0A7I2V5M1|A0A7I2V5M1_HUMAN,tr|A0A7I2V5K3|A0A7I2V5K3_HUMAN,tr|A0A7I2V369|A0A7I2V369_HUMAN" 8 1090.5883 1.25 32637 17408 2 1090.588334 546.3014 "60 kDa heat shock protein, mitochondrial OS=Homo sapiens OX=9606 GN=HSPD1 PE=1 SV=2" 7.18 3033.3 - 901955 - - - -0.0073 - 2.687 0.454 - 774.5 1 1 0 0 10 0 0 0 8.35E+06 6.66E+06 - - - 5.1532 1 221125_WJC_METTL3_EV_vs_WT_F03.17409.17409.2 2.68E-06 16/26 R.LLLQQSIGETNVER[166.11].K "sp|Q8TBK6|ZCH10_HUMAN,tr|B3KVL5|B3KVL5_HUMAN" 2 1608.8711 0.87 32638 17409 2 1608.87004 805.4428 Zinc finger CCHC domain-containing protein 10 OS=Homo sapiens OX=9606 GN=ZCCHC10 PE=1 SV=1 4.53 3033.5 - 862628 - - - -0.6309 - 3.327 0.601 - 908 1 2 0 -0.001 14 0 0 0 6.94E+06 7.96E+06 - - - 6.4962 0.996 221125_WJC_METTL3_EV_vs_WT_F03.17411.17411.3 0.0111 Nov-44 R.ESVFTNER[166.11]FPLR[166.11].M sp|O43709|BUD23_HUMAN 1 1513.7792 0.86 32640 17411 3 1513.777956 505.6003 Probable 18S rRNA (guanine-N(7))-methyltransferase OS=Homo sapiens OX=9606 GN=BUD23 PE=1 SV=2 6.24 3033.7 - 829844 - - - -0.833 - 1.559 0.327 - 181 1 2 1 -0.0013 12 0 0 0 7.02E+06 8.13E+06 - - - 3.4162 1 221125_WJC_METTL3_EV_vs_WT_F03.17412.17412.2 3.95E-07 13/26 R.LLLQQSIGETNVER.K "sp|Q8TBK6|ZCH10_HUMAN,tr|B3KVL5|B3KVL5_HUMAN" 2 1598.8628 0.87 32641 17412 2 1598.862669 800.4387 Zinc finger CCHC domain-containing protein 10 OS=Homo sapiens OX=9606 GN=ZCCHC10 PE=1 SV=1 4.53 3033.8 - 798661 - - - -0.0726 - 2.869 0.6 - 529.5 1 2 0 -0.0001 14 0 0 0 6.94E+06 7.96E+06 - - - 6.1174 0.9999 221125_WJC_METTL3_EV_vs_WT_F03.17413.17413.3 0.0446 15/44 K.LAQLEAALQQAK.Q sp|Q6KB66|K2C80_HUMAN 1 1282.7245 15.31 32642 17413 3 1282.724538 428.5821 "Keratin, type II cytoskeletal 80 OS=Homo sapiens OX=9606 GN=KRT80 PE=1 SV=2" 6 3033.9 - 684167 - - - 0.0288 - 2.7 0.348 - 467.9 1 2 0 0 12 0 0 0 5.15E+06 3.36E+05 - - - 5.173 0.9999 221125_WJC_METTL3_EV_vs_WT_F03.17414.17414.3 1.41E-05 13/52 R.LLLQQSIGETNVER.K "sp|Q8TBK6|ZCH10_HUMAN,tr|B3KVL5|B3KVL5_HUMAN" 2 1598.8628 0.62 32643 17414 3 1598.865187 533.9615 Zinc finger CCHC domain-containing protein 10 OS=Homo sapiens OX=9606 GN=ZCCHC10 PE=1 SV=1 4.53 3034.1 - 665365 - - - 1.5023 - 2.72 0.407 - 290 1 2 0 0.0024 14 0 0 0 2.91E+06 4.73E+06 - - - 5.7362 0.9715 221125_WJC_METTL3_EV_vs_WT_F03.17415.17415.3 0.000925 Dec-52 R.LLLQQSIGETNVER[166.11].K "sp|Q8TBK6|ZCH10_HUMAN,tr|B3KVL5|B3KVL5_HUMAN" 2 1608.8711 0.62 32644 17415 3 1608.865059 537.2976 Zinc finger CCHC domain-containing protein 10 OS=Homo sapiens OX=9606 GN=ZCCHC10 PE=1 SV=1 4.53 3034.2 - 662554 - - - -3.7268 - 2.16 0.153 - 194.1 1 2 0 -0.006 14 0 0 0 2.91E+06 4.73E+06 - - - 2.2907 0.9951 221125_WJC_METTL3_EV_vs_WT_F03.17416.17416.2 0.0357 24-Aug R.IVFTITTGAGSAK.Q sp|Q8TEK3|DOT1L_HUMAN 1 1264.7027 2.16 32645 17416 2 1264.70314 633.3586 "Histone-lysine N-methyltransferase, H3 lysine-79 specific OS=Homo sapiens OX=9606 GN=DOT1L PE=1 SV=3" 8.75 3034.3 - 630736 - - - 0.3455 - 1.408 0.185 - 164.5 2 2 0 0.0004 13 0 0 0 1.05E+07 4.88E+06 - - - 1.151 0.9805 221125_WJC_METTL3_EV_vs_WT_F03.17420.17420.2 2.71E-08 13/26 F.GTLSPSLGNSSILK.T sp|P49790|NU153_HUMAN 1 1372.7562 0.85 32648 17420 2 1372.752275 687.3854 Nuclear pore complex protein Nup153 OS=Homo sapiens OX=9606 GN=NUP153 PE=1 SV=2 8.75 3034.7 - 4.14E+06 - - - -2.8556 - 2.631 0.572 - 540.6 1 1 0 -0.0039 14 0 0 0 2.28E+07 2.69E+07 - - - 5.6921 0.9883 221125_WJC_METTL3_EV_vs_WT_F03.17421.17421.2 0.0033 24-Sep K.VIGGDDLSTLTGK[136.11].N sp|P00492|HPRT_HUMAN 1 1282.686 0.76 32649 17421 2 1282.684886 642.3503 Hypoxanthine-guanine phosphoribosyltransferase OS=Homo sapiens OX=9606 GN=HPRT1 PE=1 SV=2 4.21 3034.7 - 3.16E+06 - - - -0.8662 - 1.616 0.073 - 112.9 3 2 0 -0.0011 13 0 0 0 2.04E+07 2.68E+07 - - - 0.5985 1 221125_WJC_METTL3_EV_vs_WT_F03.17422.17422.2 1.67E-09 22-Nov K.VLISDSLDPC[160.03]C[160.03]R.K "sp|O43175|SERA_HUMAN,tr|A0A2C9F2M7|A0A2C9F2M7_HUMAN,tr|A0A286YFB2|A0A286YFB2_HUMAN,tr|A0A286YF34|A0A286YF34_HUMAN,tr|A0A286YFC8|A0A286YFC8_HUMAN,tr|A0A286YF22|A0A286YF22_HUMAN,tr|A0A286YFL2|A0A286YFL2_HUMAN,tr|A0A286YFA2|A0A286YFA2_HUMAN,tr|A0A286YFM8|A0A286YFM8_HUMAN,tr|A0A286YER3|A0A286YER3_HUMAN,tr|A0A286YFF3|A0A286YFF3_HUMAN,tr|A0A286YFK5|A0A286YFK5_HUMAN" 12 1433.6643 1.26 32650 17422 2 1433.664745 717.8394 D-3-phosphoglycerate dehydrogenase OS=Homo sapiens OX=9606 GN=PHGDH PE=1 SV=4 4.21 3034.8 - 3.14E+06 - - - 0.3202 - 2.343 0.603 - 353 1 2 0 0.0005 12 0 0 0 3.99E+07 3.16E+07 - - - 5.7349 0.9998 221125_WJC_METTL3_EV_vs_WT_F03.17423.17423.2 0.000885 18-Oct K.SQSLLTFSTK.S sp|Q8IWA0|WDR75_HUMAN 1 1110.5921 1.29 32651 17423 2 1110.592197 556.3033 WD repeat-containing protein 75 OS=Homo sapiens OX=9606 GN=WDR75 PE=1 SV=1 8.47 3034.9 - 2.88E+06 - - - 0.0963 - 1.861 0.428 - 396.8 1 2 0 0.0001 10 0 0 0 1.64E+07 1.26E+07 - - - 3.9359 0.9999 221125_WJC_METTL3_EV_vs_WT_F03.17424.17424.3 0.000378 Nov-40 K.LSTDHIPILYR[166.11].T "sp|Q06210|GFPT1_HUMAN,tr|A0A6I8PRN4|A0A6I8PRN4_HUMAN,tr|A0A6I8PTT9|A0A6I8PTT9_HUMAN" 3 1336.7379 1.13 32652 17424 3 1336.738095 446.5866 Glutamine--fructose-6-phosphate aminotransferase [isomerizing] 1 OS=Homo sapiens OX=9606 GN=GFPT1 PE=1 SV=3 6.74 3034.9 - 1.95E+06 - - - 0.1788 - 2.142 0.432 - 153.5 1 2 0 0.0002 11 0 0 0 1.02E+08 9.02E+07 - - - 5.5203 1 221125_WJC_METTL3_EV_vs_WT_F03.17425.17425.3 4.42E-06 14/52 K.VPQVSTPTLVEVSR.N "sp|P02768|ALBU_HUMAN,tr|A0A087WWT3|A0A087WWT3_HUMAN,tr|B7WNR0|B7WNR0_HUMAN,tr|H0YA55|H0YA55_HUMAN,tr|A0A0C4DGB6|A0A0C4DGB6_HUMAN,tr|D6RHD5|D6RHD5_HUMAN,tr|C9JKR2|C9JKR2_HUMAN" 7 1510.8355 40.02 32653 17425 3 1510.834391 504.6191 Albumin OS=Homo sapiens OX=9606 GN=ALB PE=1 SV=2 5.97 3035 - 1.31E+06 - - - -0.7393 - 2.633 0.477 - 324.9 1 2 0 -0.0011 14 0 0 0 5.70E+06 1.42E+05 - - - 6.4306 0.9997 221125_WJC_METTL3_EV_vs_WT_F03.17427.17427.2 0.000153 18-Oct R.GFNLPYQDAR[166.11].K "sp|Q8NE71|ABCF1_HUMAN,tr|A0A0G2JIC2|A0A0G2JIC2_HUMAN,tr|Q5STZ8|Q5STZ8_HUMAN,tr|H0YGW7|H0YGW7_HUMAN" 4 1189.5755 1.02 32655 17427 2 1189.574412 595.795 ATP-binding cassette sub-family F member 1 OS=Homo sapiens OX=9606 GN=ABCF1 PE=1 SV=2 5.84 3035.3 - 1.09E+06 - - - -0.9499 - 1.633 0.438 - 363.5 1 2 0 -0.0011 10 0 0 0 4.14E+07 4.04E+07 - - - 3.6446 0.9994 221125_WJC_METTL3_EV_vs_WT_F03.17428.17428.2 0.000185 20-Nov K.LEQLFQDEVAK.A "sp|Q15149|PLEC_HUMAN,tr|H0YDN1|H0YDN1_HUMAN" 2 1318.6769 0.68 32656 17428 2 1318.676184 660.3457 Plectin OS=Homo sapiens OX=9606 GN=PLEC PE=1 SV=3 4.14 3035.4 - 1.01E+06 - - - -0.5293 - 2.25 0.221 - 509.6 1 2 0 -0.0007 11 0 0 0 5.23E+06 7.69E+06 - - - 2.8668 0.9926 221125_WJC_METTL3_EV_vs_WT_F03.17430.17430.2 8.41E-06 24-Oct Q.SIVPALEIANAHR.K "sp|P10809|CH60_HUMAN,tr|A0A7I2V2X6|A0A7I2V2X6_HUMAN,tr|A0A7I2YQK6|A0A7I2YQK6_HUMAN,tr|A0A7I2V599|A0A7I2V599_HUMAN,tr|A0A7I2YQ71|A0A7I2YQ71_HUMAN,tr|A0A7I2V5M1|A0A7I2V5M1_HUMAN,tr|A0A7I2V5K3|A0A7I2V5K3_HUMAN,tr|A0A7I2V369|A0A7I2V369_HUMAN" 8 1389.7728 2.29 32658 17430 2 1389.773587 695.8937 "60 kDa heat shock protein, mitochondrial OS=Homo sapiens OX=9606 GN=HSPD1 PE=1 SV=2" 6.47 3035.6 - 956953 - - - 0.5317 - 2.224 0.528 - 315 1 1 0 0.0007 13 0 0 0 6.78E+06 2.95E+06 - - - 4.992 0.9998 221125_WJC_METTL3_EV_vs_WT_F03.17434.17434.3 0.0186 14/48 R.R[166.11]IVPGQFLAVDPK[136.11].G sp|Q15393|SF3B3_HUMAN 1 1456.8521 1.58 32662 17434 3 1456.852383 486.6246 Splicing factor 3B subunit 3 OS=Homo sapiens OX=9606 GN=SF3B3 PE=1 SV=4 8.75 3036.1 - 534024 - - - 0.1908 - 2.154 0.346 - 210 1 2 0 0.0003 13 0 0 0 8.34E+06 5.29E+06 - - - 4.4779 1 221125_WJC_METTL3_EV_vs_WT_F03.17436.17436.2 2.76E-09 14/28 R.EIQEAIAVANASTMH.- sp|Q2TAL8|QRIC1_HUMAN 1 1583.7614 - 32664 17436 2 1583.761708 792.888 Transcriptional regulator QRICH1 OS=Homo sapiens OX=9606 GN=QRICH1 PE=1 SV=1 4.51 3036.4 - 347051 - - - 0.2216 - 2.76 0.571 - 737.4 1 2 0 0.0004 15 0 0 0 - - - - - 5.7543 1 221125_WJC_METTL3_EV_vs_WT_F03.17437.17437.2 3.51E-12 14/34 K.MVMIQDGPLPTGADK[136.11]PLR[166.11].L sp|Q96I24|FUBP3_HUMAN 1 1956.0292 1.2 32665 17437 2 1956.032521 979.0219 Far upstream element-binding protein 3 OS=Homo sapiens OX=9606 GN=FUBP3 PE=1 SV=2 5.71 3036.5 - 342200 - - - 1.7188 - 2.935 0.742 - 544.2 1 2 0 0.0034 18 0 0 0 2.69E+06 2.25E+06 - - - 7.1675 0.9926 221125_WJC_METTL3_EV_vs_WT_F03.17438.17438.3 0.108 Aug-44 R.K[136.11]LNAFGNAFLNR[166.11].F "sp|Q9NZN3|EHD3_HUMAN,sp|Q9H4M9|EHD1_HUMAN,tr|C9JC03|C9JC03_HUMAN,tr|C9JIJ3|C9JIJ3_HUMAN,tr|C9IZH1|C9IZH1_HUMAN,tr|A0A024R571|A0A024R571_HUMAN" 6 1381.7585 0.39 32666 17438 3 1381.760056 461.5935 EH domain-containing protein 3 OS=Homo sapiens OX=9606 GN=EHD3 PE=1 SV=2 11 3036.6 - 281458 - - - 1.0986 - 1.663 0.191 - 62.3 1 2 0 0.0015 12 0 0 0 6.68E+05 1.73E+06 - - - 2.0789 1 221125_WJC_METTL3_EV_vs_WT_F03.17442.17442.3 9.24E-12 26/80 R.VTGEADVEFATHEDAVAAMSK[136.11].D "sp|P31943|HNRH1_HUMAN,tr|H0YBD7|H0YBD7_HUMAN,tr|H0YB39|H0YB39_HUMAN,tr|H0YBG7|H0YBG7_HUMAN,tr|E9PCY7|E9PCY7_HUMAN,tr|G8JLB6|G8JLB6_HUMAN" 6 2185.0089 1.22 32669 17442 3 2185.007766 729.3436 Heterogeneous nuclear ribonucleoprotein H OS=Homo sapiens OX=9606 GN=HNRNPH1 PE=1 SV=4 4.17 3037.1 - 5.30E+06 - - - -0.5025 - 5.088 0.678 - 753.2 1 2 0 -0.0011 21 0 0 0 1.73E+08 1.41E+08 - - - 9.9991 1 221125_WJC_METTL3_EV_vs_WT_F03.17443.17443.2 2.00E-09 22-Dec K.VLISDSLDPC[160.03]C[160.03]R[166.11].K "sp|O43175|SERA_HUMAN,tr|A0A2C9F2M7|A0A2C9F2M7_HUMAN,tr|A0A286YFB2|A0A286YFB2_HUMAN,tr|A0A286YF34|A0A286YF34_HUMAN,tr|A0A286YFC8|A0A286YFC8_HUMAN,tr|A0A286YF22|A0A286YF22_HUMAN,tr|A0A286YFL2|A0A286YFL2_HUMAN,tr|A0A286YFA2|A0A286YFA2_HUMAN,tr|A0A286YFM8|A0A286YFM8_HUMAN,tr|A0A286YER3|A0A286YER3_HUMAN,tr|A0A286YFF3|A0A286YFF3_HUMAN,tr|A0A286YFK5|A0A286YFK5_HUMAN" 12 1443.6726 1.26 32670 17443 2 1443.671687 722.8436 D-3-phosphoglycerate dehydrogenase OS=Homo sapiens OX=9606 GN=PHGDH PE=1 SV=4 4.21 3037.1 - 3.59E+06 - - - -0.6019 - 2.373 0.634 - 410.3 1 2 0 -0.0009 12 0 0 0 3.99E+07 3.16E+07 - - - 5.9972 0.9996 221125_WJC_METTL3_EV_vs_WT_F03.17444.17444.2 0.000106 26-Dec K.VPQVSTPTLVEVSR.N "sp|P02768|ALBU_HUMAN,tr|A0A087WWT3|A0A087WWT3_HUMAN,tr|B7WNR0|B7WNR0_HUMAN,tr|H0YA55|H0YA55_HUMAN,tr|A0A0C4DGB6|A0A0C4DGB6_HUMAN,tr|D6RHD5|D6RHD5_HUMAN,tr|C9JKR2|C9JKR2_HUMAN" 7 1510.8355 999 32671 17444 2 1510.839178 756.425 Albumin OS=Homo sapiens OX=9606 GN=ALB PE=1 SV=2 5.97 3037.2 - 3.02E+06 - - - 2.4291 - 2.282 0.486 - 422.7 1 2 0 0.0037 14 0 0 0 2.13E+07 0.00E+00 - - - 4.6999 0.9998 221125_WJC_METTL3_EV_vs_WT_F03.17449.17449.2 0.00132 13/24 R.NILLTNEQLESAR.K "sp|Q9H9B4|SFXN1_HUMAN,tr|H0Y9J5|H0Y9J5_HUMAN,tr|D6RFI0|D6RFI0_HUMAN,tr|D6RDG7|D6RDG7_HUMAN,tr|S4R2X2|S4R2X2_HUMAN,tr|D6RAE9|D6RAE9_HUMAN" 6 1499.7944 1.27 32676 17449 2 1499.796338 750.9045 Sideroflexin-1 OS=Homo sapiens OX=9606 GN=SFXN1 PE=1 SV=4 4.53 3037.6 - 1.54E+06 - - - 1.3115 - 2.522 0.518 - 547.2 1 2 0 0.002 13 0 0 0 2.92E+07 2.29E+07 - - - 5.2405 0.9844 221125_WJC_METTL3_EV_vs_WT_F03.17450.17450.2 0.00258 13/18 V.PALEIANAHR[166.11].K "sp|P10809|CH60_HUMAN,tr|A0A7I2V2X6|A0A7I2V2X6_HUMAN,tr|A0A7I2YQK6|A0A7I2YQK6_HUMAN,tr|A0A7I2V599|A0A7I2V599_HUMAN,tr|A0A7I2YQ71|A0A7I2YQ71_HUMAN,tr|A0A7I2V5M1|A0A7I2V5M1_HUMAN,tr|A0A7I2V5K3|A0A7I2V5K3_HUMAN,tr|A0A7I2V369|A0A7I2V369_HUMAN" 8 1100.5966 1.43 32677 17450 2 1100.595444 551.3056 "60 kDa heat shock protein, mitochondrial OS=Homo sapiens OX=9606 GN=HSPD1 PE=1 SV=2" 7.18 3037.7 - 1.34E+06 - - - -1.0612 - 2.686 0.297 - 805.4 1 1 0 -0.0012 10 0 0 0 4.33E+07 3.02E+07 - - - 3.9922 0.9998 221125_WJC_METTL3_EV_vs_WT_F03.17452.17452.2 8.74E-06 14/26 R.DVVIC[160.03]PDASLEDAK[136.11].K "sp|Q99497|PARK7_HUMAN,tr|K7EN27|K7EN27_HUMAN,tr|K7ELW0|K7ELW0_HUMAN" 3 1538.7378 2.43 32679 17452 2 1538.735941 770.3762 Parkinson disease protein 7 OS=Homo sapiens OX=9606 GN=PARK7 PE=1 SV=2 3.84 3037.9 - 1.31E+06 - - - -1.1912 - 2.687 0.458 - 611.1 1 2 0 -0.0018 14 0 0 0 4.62E+07 1.90E+07 - - - 4.9036 1 221125_WJC_METTL3_EV_vs_WT_F03.17453.17453.3 0.000167 13/44 K.TPIQVLHEYGMK.T "sp|O75569|PRKRA_HUMAN,tr|A0A7I2V5C2|A0A7I2V5C2_HUMAN,tr|A0A7I2V5H3|A0A7I2V5H3_HUMAN,tr|A0A7I2V2P4|A0A7I2V2P4_HUMAN,tr|F8WEG8|F8WEG8_HUMAN,tr|G5E9Q4|G5E9Q4_HUMAN,tr|A0A7I2YQ87|A0A7I2YQ87_HUMAN,tr|C9JMM3|C9JMM3_HUMAN,tr|A0A7I2V3L6|A0A7I2V3L6_HUMAN" 9 1414.7279 0.85 32680 17453 3 1414.728608 472.5832 Interferon-inducible double-stranded RNA-dependent protein kinase activator A OS=Homo sapiens OX=9606 GN=PRKRA PE=1 SV=1 6.41 3038 - 971096 - - - 0.5202 - 2.52 0.481 - 254.3 1 2 0 0.0007 12 0 0 0 1.61E+07 1.90E+07 - - - 6.4644 0.9996 221125_WJC_METTL3_EV_vs_WT_F03.17454.17454.2 0.00312 20-Aug R.LMMDPLSGQNR.G "sp|O43390|HNRPR_HUMAN,tr|B4DT28|B4DT28_HUMAN,tr|A0A6Q8PH31|A0A6Q8PH31_HUMAN,tr|A0A6Q8PEX7|A0A6Q8PEX7_HUMAN,tr|A0A6Q8PH35|A0A6Q8PH35_HUMAN" 5 1260.5955 1.47 32681 17454 2 1260.593503 631.305 Heterogeneous nuclear ribonucleoprotein R OS=Homo sapiens OX=9606 GN=HNRNPR PE=1 SV=1 5.84 3038.1 - 795720 - - - -1.5659 - 1.871 0.433 - 212.6 1 2 0 -0.002 11 0 0 0 5.97E+06 4.06E+06 - - - 3.9333 0.9992 221125_WJC_METTL3_EV_vs_WT_F03.17455.17455.2 1.62E-06 13/22 K.VDFTEEEINNMK.T "sp|P46940|IQGA1_HUMAN,tr|A0A0J9YXZ5|A0A0J9YXZ5_HUMAN,tr|H0YKA5|H0YKA5_HUMAN" 3 1467.6552 1.41 32682 17455 2 1467.659212 734.8349 Ras GTPase-activating-like protein IQGAP1 OS=Homo sapiens OX=9606 GN=IQGAP1 PE=1 SV=1 4 3038.3 - 782232 - - - 2.7609 - 2.637 0.334 - 515.9 1 2 0 0.0041 12 0 0 0 3.52E+06 2.49E+06 - - - 4.0579 0.9872 221125_WJC_METTL3_EV_vs_WT_F03.17456.17456.2 0.0239 20-Oct N.GITLPVDPEGK.L sp|P52597|HNRPF_HUMAN 1 1124.6077 0.55 32683 17456 2 1124.608038 563.3111 Heterogeneous nuclear ribonucleoprotein F OS=Homo sapiens OX=9606 GN=HNRNPF PE=1 SV=3 4.37 3038.4 - 773037 - - - 0.265 - 2.028 0.415 - 296.8 1 1 0 0.0003 11 0 0 0 8.91E+06 1.63E+07 - - - 4.0188 0.9983 221125_WJC_METTL3_EV_vs_WT_F03.17459.17459.2 9.82E-07 24-Nov K.AMQEQLENYDFTK.F sp|Q9H223|EHD4_HUMAN 1 1615.7188 -1 32686 17459 2 1615.710964 808.8667 EH domain-containing protein 4 OS=Homo sapiens OX=9606 GN=EHD4 PE=1 SV=1 4.14 3038.8 - 474423 - - - -4.8641 - 2.513 0.531 - 478.7 1 2 0 -0.0079 13 0 0 0 0.00E+00 0.00E+00 - - - 5.3255 0.9945 221125_WJC_METTL3_EV_vs_WT_F03.17461.17461.2 1.33E-06 13/28 K.SGPVMGGGLPPPPIK[136.11].H sp|Q9BYJ9|YTHD1_HUMAN 1 1410.7785 0.05 32687 17461 2 1410.78167 706.3965 YTH domain-containing family protein 1 OS=Homo sapiens OX=9606 GN=YTHDF1 PE=1 SV=1 8.47 3039 - 1.59E+06 - - - 2.2775 - 2.374 0.103 - 401.1 2 2 0 0.0032 15 0 0 0 3.13E+07 5.77E+08 - - - 1.7919 0.9954 221125_WJC_METTL3_EV_vs_WT_F03.17462.17462.3 0.198 Dec-56 K.C[160.03]VTTELYADSSQLSR[166.11].E "sp|Q6W2J9|BCOR_HUMAN,tr|H7BZ37|H7BZ37_HUMAN,tr|A1A564|A1A564_HUMAN,tr|H7C2V9|H7C2V9_HUMAN,tr|H7BYY2|H7BYY2_HUMAN,tr|H7C231|H7C231_HUMAN" 6 1738.8071 -1 32688 17462 3 1738.807344 580.6097 BCL-6 corepressor OS=Homo sapiens OX=9606 GN=BCOR PE=1 SV=1 4.37 3039.1 - 1.29E+06 - - - 0.1202 - 1.746 0.206 - 133 1 2 0 0.0002 15 0 0 0 0.00E+00 0.00E+00 - - - 2.2909 1 221125_WJC_METTL3_EV_vs_WT_F03.17464.17464.3 7.60E-05 13/44 R.LNHLVDSLQQLR.L "sp|P35658|NU214_HUMAN,tr|A0A0A0MSW3|A0A0A0MSW3_HUMAN,tr|A0A494C1F2|A0A494C1F2_HUMAN" 3 1434.7943 1.94 32690 17464 3 1434.794549 479.272 Nuclear pore complex protein Nup214 OS=Homo sapiens OX=9606 GN=NUP214 PE=1 SV=2 6.74 3039.2 - 3.57E+06 - - - 0.1652 - 2.51 0.494 - 239.1 1 2 0 0.0002 12 0 0 0 5.67E+07 2.92E+07 - - - 6.5984 1 221125_WJC_METTL3_EV_vs_WT_F03.17465.17465.3 4.52E-06 Nov-48 R.FGDDLNHISC[160.03]VIK.E "sp|Q8IXM2|BAP18_HUMAN,tr|H0YIS7|H0YIS7_HUMAN,tr|F8W038|F8W038_HUMAN,tr|F8W1H0|F8W1H0_HUMAN" 4 1516.7344 2.25 32691 17465 3 1516.735015 506.5854 Chromatin complexes subunit BAP18 OS=Homo sapiens OX=9606 GN=BAP18 PE=1 SV=1 5.21 3039.3 - 2.72E+06 - - - 0.3962 - 1.94 0.503 - 65.5 1 2 0 0.0006 13 0 0 0 3.38E+07 1.50E+07 - - - 5.9445 1 221125_WJC_METTL3_EV_vs_WT_F03.17466.17466.3 7.17E-06 13/44 R.LNHLVDSLQQLR[166.11].L "sp|P35658|NU214_HUMAN,tr|A0A0A0MSW3|A0A0A0MSW3_HUMAN,tr|A0A494C1F2|A0A494C1F2_HUMAN" 3 1444.8026 1.9 32692 17466 3 1444.802753 482.6081 Nuclear pore complex protein Nup214 OS=Homo sapiens OX=9606 GN=NUP214 PE=1 SV=2 6.74 3039.3 - 2.28E+06 - - - 0.1184 - 2.541 0.431 - 309.7 1 2 0 0.0002 12 0 0 0 5.47E+07 2.88E+07 - - - 5.9301 0.9999 221125_WJC_METTL3_EV_vs_WT_F03.17467.17467.2 1.47E-10 13/34 R.FSPDGELYASGSEDGTLR[166.11].L "sp|Q9Y3F4|STRAP_HUMAN,tr|H0YH33|H0YH33_HUMAN" 2 1909.8569 0.78 32693 17467 2 1909.857359 955.9357 Serine-threonine kinase receptor-associated protein OS=Homo sapiens OX=9606 GN=STRAP PE=1 SV=1 3.92 3039.4 - 1.11E+06 - - - 0.2293 - 2.745 0.565 - 386.5 1 2 0 0.0004 18 0 0 0 2.35E+07 3.01E+07 - - - 5.6965 0.9999 221125_WJC_METTL3_EV_vs_WT_F03.17468.17468.3 4.26E-05 13/56 K.EALGGQALYPHVLVK.N "sp|Q9BUJ2|HNRL1_HUMAN,tr|M0QYZ0|M0QYZ0_HUMAN,tr|A0A0A0MRA5|A0A0A0MRA5_HUMAN,tr|M0R3F1|M0R3F1_HUMAN,tr|B7Z4B8|B7Z4B8_HUMAN" 5 1593.8879 1.54 32694 17468 3 1593.889342 532.3032 Heterogeneous nuclear ribonucleoprotein U-like protein 1 OS=Homo sapiens OX=9606 GN=HNRNPUL1 PE=1 SV=2 6.85 3039.5 - 959029 - - - 0.9185 - 2.504 0.399 - 244.9 1 2 0 0.0015 15 0 0 0 5.28E+07 3.43E+07 - - - 5.3832 1 221125_WJC_METTL3_EV_vs_WT_F03.17469.17469.2 1.97E-08 17/26 K.GFALVGVGSEASSK[136.11].K "sp|Q16630|CPSF6_HUMAN,tr|F8WJN3|F8WJN3_HUMAN" 2 1315.6863 0.91 32695 17469 2 1315.691262 658.8504 Cleavage and polyadenylation specificity factor subunit 6 OS=Homo sapiens OX=9606 GN=CPSF6 PE=1 SV=2 6 3039.7 - 886341 - - - 3.7479 - 3.245 0.605 - 921.5 1 2 0 0.0049 14 0 0 0 1.34E+07 1.47E+07 - - - 6.4619 0.987 221125_WJC_METTL3_EV_vs_WT_F03.17470.17470.3 6.06E-07 16/60 K.FMADC[160.03]PHTIGVEFGTR[166.11].L "sp|P61106|RAB14_HUMAN,tr|X6RFL8|X6RFL8_HUMAN" 2 1846.837 2.05 32696 17470 3 1847.831962 616.6196 Ras-related protein Rab-14 OS=Homo sapiens OX=9606 GN=RAB14 PE=1 SV=4 5.32 3039.8 - 736320 - - - 538.7411 - 2.367 0.511 - 228.2 1 2 0 0.995 16 0 0 0 7.60E+06 3.71E+06 - - - 6.1723 0.9999 221125_WJC_METTL3_EV_vs_WT_F03.17472.17472.2 4.64E-08 17/30 K.VFVGGLSPDTSEEQIK.E "sp|O14979|HNRDL_HUMAN,tr|A0A087WUK2|A0A087WUK2_HUMAN" 2 1704.857 1.28 32698 17472 2 1704.856181 853.4358 Heterogeneous nuclear ribonucleoprotein D-like OS=Homo sapiens OX=9606 GN=HNRNPDL PE=1 SV=3 4.14 3040 - 598415 - - - -0.4986 - 3.119 0.525 - 667.8 1 2 0 -0.0008 16 0 0 0 6.78E+07 5.28E+07 - - - 5.715 1 221125_WJC_METTL3_EV_vs_WT_F03.17476.17476.2 6.59E-08 13/34 K.TVAGGAWTYNTTSAVTVK[136.11].S "sp|P61513|RL37A_HUMAN,tr|C9J4Z3|C9J4Z3_HUMAN" 2 1833.9352 3.27 32702 17476 2 1833.937167 917.9749 60S ribosomal protein L37a OS=Homo sapiens OX=9606 GN=RPL37A PE=1 SV=2 8.26 3040.6 - 338325 - - - 1.0573 - 2.626 0.632 - 355.1 1 2 0 0.0019 18 0 0 0 1.63E+07 4.98E+06 - - - 6.082 0.9999 221125_WJC_METTL3_EV_vs_WT_F03.17477.17477.3 0.000556 Oct-40 R.AFHPDLEFVGK.F sp|O95864|FADS2_HUMAN 1 1258.6346 0.94 32703 17477 3 1258.636269 420.5522 Acyl-CoA 6-desaturase OS=Homo sapiens OX=9606 GN=FADS2 PE=1 SV=1 5.32 3040.7 - 337665 - - - 1.3078 - 2.086 0.437 - 146.7 1 2 0 0.0016 11 0 0 0 1.94E+06 2.07E+06 - - - 5.5004 0.9998 221125_WJC_METTL3_EV_vs_WT_F03.17480.17480.3 0.00265 13/40 R.LAPALPAWPHR[166.11].G sp|Q96P11|NSUN5_HUMAN 1 1237.6959 0.94 32706 17480 3 1237.695339 413.5726 28S rRNA (cytosine-C(5))-methyltransferase OS=Homo sapiens OX=9606 GN=NSUN5 PE=1 SV=2 9.76 3041.1 - 245162 - - - -0.4791 - 2.083 0.35 - 211.8 1 2 0 -0.0006 11 0 0 0 2.43E+06 2.59E+06 - - - 4.5266 0.9998 221125_WJC_METTL3_EV_vs_WT_F03.17483.17483.3 0.00162 Oct-40 R.LAPALPAWPHR.G sp|Q96P11|NSUN5_HUMAN 1 1227.6877 0.35 32708 17483 3 1227.688845 410.2365 28S rRNA (cytosine-C(5))-methyltransferase OS=Homo sapiens OX=9606 GN=NSUN5 PE=1 SV=2 9.76 3041.6 - 238903 - - - 0.9636 - 1.762 0.401 - 113.8 1 2 0 0.0012 11 0 0 0 2.07E+06 5.90E+06 - - - 4.6196 0.9997 221125_WJC_METTL3_EV_vs_WT_F03.17485.17485.2 1.11 18-Oct K.YQELINDIAR[166.11].D "sp|P46940|IQGA1_HUMAN,tr|H0YLE8|H0YLE8_HUMAN" 2 1243.6436 0.88 32710 17485 2 1243.645056 622.8291 Ras GTPase-activating-like protein IQGAP1 OS=Homo sapiens OX=9606 GN=IQGAP1 PE=1 SV=1 4.37 3041.7 - 2.28E+06 - - - 1.1539 - 1.993 0.41 - 285.6 1 2 0 0.0014 10 0 0 0 2.97E+07 3.40E+07 - - - 3.9938 0.9995 221125_WJC_METTL3_EV_vs_WT_F03.17486.17486.2 0.0197 18-Sep K.ISYSGQFLVK.S sp|Q9NZI8|IF2B1_HUMAN 1 1140.6179 1.97 32711 17486 2 1140.617238 571.3162 Insulin-like growth factor 2 mRNA-binding protein 1 OS=Homo sapiens OX=9606 GN=IGF2BP1 PE=1 SV=2 8.59 3041.7 - 1.83E+06 - - - -0.5892 - 1.592 0.368 - 172.1 1 2 0 -0.0007 10 0 0 0 1.28E+07 6.50E+06 - - - 3.0568 0.9989 221125_WJC_METTL3_EV_vs_WT_F03.17487.17487.2 0.0269 18-Jul K.ISYSGQFLVK[136.11].S sp|Q9NZI8|IF2B1_HUMAN 1 1148.6321 1.95 32712 17487 2 1148.632849 575.3233 Insulin-like growth factor 2 mRNA-binding protein 1 OS=Homo sapiens OX=9606 GN=IGF2BP1 PE=1 SV=2 8.59 3041.8 - 1.30E+06 - - - 0.6434 - 1.452 0.313 - 81.2 1 2 0 0.0007 10 0 0 0 1.27E+07 6.50E+06 - - - 2.3936 0.9925 221125_WJC_METTL3_EV_vs_WT_F03.17488.17488.2 0.000167 13/24 Q.SIVPALEIANAHR[166.11].K "sp|P10809|CH60_HUMAN,tr|A0A7I2V2X6|A0A7I2V2X6_HUMAN,tr|A0A7I2YQK6|A0A7I2YQK6_HUMAN,tr|A0A7I2V599|A0A7I2V599_HUMAN,tr|A0A7I2YQ71|A0A7I2YQ71_HUMAN,tr|A0A7I2V5M1|A0A7I2V5M1_HUMAN,tr|A0A7I2V5K3|A0A7I2V5K3_HUMAN,tr|A0A7I2V369|A0A7I2V369_HUMAN" 8 1399.7811 1.46 32713 17488 2 1399.780289 700.8978 "60 kDa heat shock protein, mitochondrial OS=Homo sapiens OX=9606 GN=HSPD1 PE=1 SV=2" 6.47 3041.9 - 1.26E+06 - - - -0.5922 - 2.422 0.481 - 594.2 1 1 0 -0.0008 13 0 0 0 4.72E+07 3.23E+07 - - - 4.8637 0.9877 221125_WJC_METTL3_EV_vs_WT_F03.17490.17490.2 0.000176 15/24 R.FGDDLNHISC[160.03]VIK.E "sp|Q8IXM2|BAP18_HUMAN,tr|H0YIS7|H0YIS7_HUMAN,tr|F8W038|F8W038_HUMAN,tr|F8W1H0|F8W1H0_HUMAN" 4 1516.7344 4.39 32715 17490 2 1517.7372 759.3745 Chromatin complexes subunit BAP18 OS=Homo sapiens OX=9606 GN=BAP18 PE=1 SV=1 5.21 3042.1 - 995855 - - - 661.148 - 1.875 0.438 - 622.4 1 2 0 1.0028 13 0 0 0 1.67E+07 3.81E+06 - - - 3.5745 0.9888 221125_WJC_METTL3_EV_vs_WT_F03.17491.17491.2 4.71E-05 14/20 L.VPALEIANAHR.K "sp|P10809|CH60_HUMAN,tr|A0A7I2V2X6|A0A7I2V2X6_HUMAN,tr|A0A7I2YQK6|A0A7I2YQK6_HUMAN,tr|A0A7I2V599|A0A7I2V599_HUMAN,tr|A0A7I2YQ71|A0A7I2YQ71_HUMAN,tr|A0A7I2V5M1|A0A7I2V5M1_HUMAN,tr|A0A7I2V5K3|A0A7I2V5K3_HUMAN,tr|A0A7I2V369|A0A7I2V369_HUMAN" 8 1189.6568 1.13 32716 17491 2 1189.658027 595.8357 "60 kDa heat shock protein, mitochondrial OS=Homo sapiens OX=9606 GN=HSPD1 PE=1 SV=2" 6.72 3042.3 - 938155 - - - 1.0692 - 2.477 0.424 - 929.3 1 1 0 0.0013 11 0 0 0 2.25E+07 1.99E+07 - - - 4.626 0.9997 221125_WJC_METTL3_EV_vs_WT_F03.17492.17492.3 0.00113 13/44 R.DVR[166.11]PYIVGAVVR[166.11].G sp|Q8N1G4|LRC47_HUMAN 1 1362.7887 0.84 32717 17492 3 1362.78991 455.2702 Leucine-rich repeat-containing protein 47 OS=Homo sapiens OX=9606 GN=LRRC47 PE=1 SV=1 8.75 3042.4 - 634097 - - - 0.9172 - 2.374 0.295 - 268.4 1 2 0 0.0013 12 0 0 0 2.24E+07 2.68E+07 - - - 4.2251 1 221125_WJC_METTL3_EV_vs_WT_F03.17493.17493.2 5.30E-10 28-Dec K.TLEPIC[160.03]DADPSALAK.Y "sp|Q5T8P6|RBM26_HUMAN,tr|A0A087X0H9|A0A087X0H9_HUMAN" 2 1599.7814 0.69 32718 17493 2 1599.784247 800.898 RNA-binding protein 26 OS=Homo sapiens OX=9606 GN=RBM26 PE=1 SV=3 4.03 3042.5 - 567741 - - - 1.7646 - 2.509 0.648 - 338.2 1 2 0 0.0028 15 0 0 0 3.18E+06 4.62E+06 - - - 6.0878 0.9999 221125_WJC_METTL3_EV_vs_WT_F03.17494.17494.2 2.24E-07 28-Dec K.TLEPIC[160.03]DADPSALAK[136.11].Y "sp|Q5T8P6|RBM26_HUMAN,tr|A0A087X0H9|A0A087X0H9_HUMAN" 2 1607.7956 0.75 32719 17494 2 1607.79335 804.9051 RNA-binding protein 26 OS=Homo sapiens OX=9606 GN=RBM26 PE=1 SV=3 4.03 3042.6 - 559478 - - - -1.4144 - 2.396 0.591 - 350.7 1 2 0 -0.0023 15 0 0 0 3.45E+06 4.62E+06 - - - 5.5537 0.9998 221125_WJC_METTL3_EV_vs_WT_F03.17495.17495.2 0.000217 18-Sep R.NNNTDLMILK[136.11].N "sp|Q99460|PSMD1_HUMAN,tr|A0A7I2V4X0|A0A7I2V4X0_HUMAN,tr|A0A7I2V2K8|A0A7I2V2K8_HUMAN,tr|A0A7I2YQY1|A0A7I2YQY1_HUMAN,tr|A0A7I2V523|A0A7I2V523_HUMAN,tr|A0A7I2V641|A0A7I2V641_HUMAN,tr|A0A7I2V491|A0A7I2V491_HUMAN,tr|A0A7I2YQI9|A0A7I2YQI9_HUMAN,tr|A0A7I2V262|A0A7I2V262_HUMAN,tr|A0A087WW66|A0A087WW66_HUMAN,tr|A0A7P0MW50|A0A7P0MW50_HUMAN,tr|A0A7I2V4A5|A0A7I2V4A5_HUMAN,tr|A0A7I2V5C8|A0A7I2V5C8_HUMAN,tr|A0A7I2V479|A0A7I2V479_HUMAN" 14 1182.6158 0.44 32720 17495 2 1182.616977 592.3152 26S proteasome non-ATPase regulatory subunit 1 OS=Homo sapiens OX=9606 GN=PSMD1 PE=1 SV=2 5.84 3042.8 - 456865 - - - 0.9885 - 2.128 0.407 - 211.2 1 2 0 0.0012 10 0 0 0 3.68E+06 8.35E+06 - - - 4.1547 0.994 221125_WJC_METTL3_EV_vs_WT_F03.17497.17497.3 0.00373 Aug-40 R.AFHPDLEFVGK[136.11].F sp|O95864|FADS2_HUMAN 1 1266.6488 0.93 32722 17497 3 1266.652148 423.2236 Acyl-CoA 6-desaturase OS=Homo sapiens OX=9606 GN=FADS2 PE=1 SV=1 5.32 3043 - 354494 - - - 2.625 - 1.659 0.255 - 83.4 1 2 0 0.0033 11 0 0 0 2.15E+06 2.31E+06 - - - 2.8201 0.9999 221125_WJC_METTL3_EV_vs_WT_F03.17501.17501.2 0.000178 20-Oct K.EVYELLDSPGK[136.11].V "sp|P22234|PUR6_HUMAN,tr|E9PBS1|E9PBS1_HUMAN" 2 1256.638 0.78 32725 17501 2 1256.637968 629.3263 Multifunctional protein ADE2 OS=Homo sapiens OX=9606 GN=PAICS PE=1 SV=3 4.14 3043.5 - 3.39E+06 - - - -0.0127 - 2.11 0.54 - 300.4 1 2 0 0 11 0 0 0 1.47E+07 1.89E+07 - - - 5.0494 0.8549 221125_WJC_METTL3_EV_vs_WT_F03.17502.17502.3 0.078 Sep-36 P.SVFLFPPKPK.D "sp|P01859|IGHG2_HUMAN,sp|P01860|IGHG3_HUMAN,sp|P01861|IGHG4_HUMAN,sp|P01857|IGHG1_HUMAN,tr|A0A4W9A917|A0A4W9A917_HUMAN,tr|A0A286YES1|A0A286YES1_HUMAN,tr|A0A0A0MS08|A0A0A0MS08_HUMAN,tr|A0A286YFJ8|A0A286YFJ8_HUMAN,tr|A0A0A0MS07|A0A0A0MS07_HUMAN,tr|A0A286YEY4|A0A286YEY4_HUMAN" 10 1158.6801 10.17 32726 17502 3 1158.679549 387.234 Immunoglobulin heavy constant gamma 2 OS=Homo sapiens OX=9606 GN=IGHG2 PE=1 SV=2 10 3043.6 - 883817 - - - -0.4902 - 1.814 0.242 - 108.8 1 1 0 -0.0006 10 0 0 0 1.01E+07 9.94E+05 - - - 2.9771 0.9998 221125_WJC_METTL3_EV_vs_WT_F03.17503.17503.2 0.000317 18-Oct K.YQELINDIAR.D "sp|P46940|IQGA1_HUMAN,tr|H0YLE8|H0YLE8_HUMAN" 2 1233.6354 0.82 32727 17503 2 1233.634716 617.825 Ras GTPase-activating-like protein IQGAP1 OS=Homo sapiens OX=9606 GN=IQGAP1 PE=1 SV=1 4.37 3043.7 - 2.71E+06 - - - -0.5147 - 1.914 0.406 - 260.6 1 2 0 -0.0006 10 0 0 0 2.61E+07 3.20E+07 - - - 3.8516 1 221125_WJC_METTL3_EV_vs_WT_F03.17504.17504.2 5.21E-06 17/30 K.VFVGGLSPDTSEEQIK[136.11].E "sp|O14979|HNRDL_HUMAN,tr|A0A087WUK2|A0A087WUK2_HUMAN" 2 1712.8712 1.28 32728 17504 2 1712.867881 857.4429 Heterogeneous nuclear ribonucleoprotein D-like OS=Homo sapiens OX=9606 GN=HNRNPDL PE=1 SV=3 4.14 3043.8 - 2.29E+06 - - - -1.9558 - 3.29 0.583 - 689.2 1 2 0 -0.0034 16 0 0 0 6.78E+07 5.28E+07 - - - 6.2738 1 221125_WJC_METTL3_EV_vs_WT_F03.17505.17505.2 5.74E-11 18/34 R.FSPDGELYASGSEDGTLR.L "sp|Q9Y3F4|STRAP_HUMAN,tr|H0YH33|H0YH33_HUMAN" 2 1899.8487 0.78 32729 17505 2 1899.847026 950.9316 Serine-threonine kinase receptor-associated protein OS=Homo sapiens OX=9606 GN=STRAP PE=1 SV=1 3.92 3043.9 - 2.06E+06 - - - -0.8553 - 3.363 0.627 - 888.6 1 2 0 -0.0016 18 0 0 0 2.35E+07 3.01E+07 - - - 6.6533 1 221125_WJC_METTL3_EV_vs_WT_F03.17506.17506.2 1.68E-06 16/26 R.AVNTQALSGAGILR.M sp|O60749|SNX2_HUMAN 1 1369.7678 0.97 32730 17506 2 1369.768202 685.8912 Sorting nexin-2 OS=Homo sapiens OX=9606 GN=SNX2 PE=1 SV=2 9.79 3044 - 1.46E+06 - - - 0.3205 - 3.216 0.58 - 915.8 1 2 0 0.0004 14 0 0 0 1.83E+07 1.89E+07 - - - 6.2561 0.9999 221125_WJC_METTL3_EV_vs_WT_F03.17508.17508.3 0.00503 16/40 R.TGFLEIDEHMR.V "sp|P35813|PPM1A_HUMAN,tr|E9PL75|E9PL75_HUMAN,tr|E9PKB5|E9PKB5_HUMAN,tr|E9PJN3|E9PJN3_HUMAN" 4 1346.6289 1.45 32732 17508 3 1346.6265 449.8836 Protein phosphatase 1A OS=Homo sapiens OX=9606 GN=PPM1A PE=1 SV=1 4.65 3044.2 - 754140 - - - -1.7718 - 2.592 0.388 - 273.2 1 2 0 -0.0024 11 0 0 0 1.58E+07 1.09E+07 - - - 5.5708 0.9994 221125_WJC_METTL3_EV_vs_WT_F03.17510.17510.2 0.000139 28-Oct R.QTGEGVGPQEYTLLK[136.11].L "sp|Q9P2J5|SYLC_HUMAN,tr|A0A6I8PIV1|A0A6I8PIV1_HUMAN,tr|A0A6I8PRS0|A0A6I8PRS0_HUMAN,tr|A0A6I8PLB8|A0A6I8PLB8_HUMAN,tr|A0A6I8PIP7|A0A6I8PIP7_HUMAN,tr|A0A6I8PIT3|A0A6I8PIT3_HUMAN,tr|A0A6I8PTV8|A0A6I8PTV8_HUMAN,tr|A0A6I8PRU9|A0A6I8PRU9_HUMAN,tr|A0A6I8PS05|A0A6I8PS05_HUMAN,tr|B4DER1|B4DER1_HUMAN,tr|A0A6I8PL42|A0A6I8PL42_HUMAN" 11 1626.8345 1.12 32734 17510 2 1626.830324 814.4245 "Leucine--tRNA ligase, cytoplasmic OS=Homo sapiens OX=9606 GN=LARS1 PE=1 SV=2" 4.53 3044.5 - 707579 - - - -2.5374 - 2.094 0.442 - 200.7 1 2 0 -0.0041 15 0 0 0 1.68E+07 1.51E+07 - - - 4.1214 1 221125_WJC_METTL3_EV_vs_WT_F03.17511.17511.2 7.76E-05 14/30 R.SLETENSALQLQVTER[166.11].E "sp|P20700|LMNB1_HUMAN,tr|A0A0D9SFY5|A0A0D9SFY5_HUMAN,tr|E9PBF6|E9PBF6_HUMAN,tr|A0A0D9SFE5|A0A0D9SFE5_HUMAN" 4 1826.9249 0.88 32735 17511 2 1826.921734 914.4697 Lamin-B1 OS=Homo sapiens OX=9606 GN=LMNB1 PE=1 SV=2 4.25 3044.6 - 512420 - - - -1.7554 - 3.082 0.562 - 632.3 1 2 0 -0.0032 16 0 0 0 1.90E+07 2.17E+07 - - - 5.9582 1 221125_WJC_METTL3_EV_vs_WT_F03.17512.17512.2 1.34E-09 15/30 R.SLETENSALQLQVTER.E "sp|P20700|LMNB1_HUMAN,tr|A0A0D9SFY5|A0A0D9SFY5_HUMAN,tr|E9PBF6|E9PBF6_HUMAN,tr|A0A0D9SFE5|A0A0D9SFE5_HUMAN" 4 1816.9167 0.81 32736 17512 2 1816.91359 909.4656 Lamin-B1 OS=Homo sapiens OX=9606 GN=LMNB1 PE=1 SV=2 4.25 3044.8 - 434007 - - - -1.6957 - 3.118 0.591 - 744.3 1 2 0 -0.0031 16 0 0 0 1.90E+07 2.34E+07 - - - 6.201 0.9998 221125_WJC_METTL3_EV_vs_WT_F03.17516.17516.2 0.000247 16/26 R.AVNTQALSGAGILR[166.11].M sp|O60749|SNX2_HUMAN 1 1379.776 0.97 32738 17516 2 1379.773102 690.8953 Sorting nexin-2 OS=Homo sapiens OX=9606 GN=SNX2 PE=1 SV=2 9.79 3045.3 - 1.93E+06 - - - -2.1243 - 2.917 0.518 - 1052.8 1 2 0 -0.0029 14 0 0 0 1.83E+07 1.89E+07 - - - 5.5525 0.9999 221125_WJC_METTL3_EV_vs_WT_F03.17522.17522.2 4.54E-05 20-Sep R.NTVEITELPVR.T "sp|Q02880|TOP2B_HUMAN,tr|E9PCY5|E9PCY5_HUMAN" 2 1269.6929 1.29 32744 17522 2 1269.693018 635.8537 DNA topoisomerase 2-beta OS=Homo sapiens OX=9606 GN=TOP2B PE=1 SV=3 4.53 3045.7 - 924469 - - - 0.1197 - 2.124 0.472 - 349.9 1 2 0 0.0002 11 0 0 0 1.83E+07 1.42E+07 - - - 4.565 0.9984 221125_WJC_METTL3_EV_vs_WT_F03.17524.17524.2 2.31E-05 22-Nov K.MQELLQTQDFSK[136.11].F "sp|Q9H4M9|EHD1_HUMAN,tr|C9J2Z4|C9J2Z4_HUMAN,tr|A0A024R571|A0A024R571_HUMAN" 3 1474.7217 1 32746 17524 2 1474.716384 738.3681 EH domain-containing protein 1 OS=Homo sapiens OX=9606 GN=EHD1 PE=1 SV=2 4.37 3046 - 525620 - - - -3.6251 - 2.477 0.338 - 486.2 1 2 0 -0.0053 12 0 0 0 4.93E+06 4.90E+06 - - - 3.9224 1 221125_WJC_METTL3_EV_vs_WT_F03.17525.17525.3 6.55E-06 14/60 R.APPNATLEHFYLTSGK[136.11].Q "sp|Q96G23|CERS2_HUMAN,tr|H0YKH6|H0YKH6_HUMAN,tr|Q5SZE4|Q5SZE4_HUMAN,tr|Q5SZE3|Q5SZE3_HUMAN,tr|Q5SZE1|Q5SZE1_HUMAN,tr|H0YNU7|H0YNU7_HUMAN,tr|Q5SZE2|Q5SZE2_HUMAN" 7 1752.8926 1.07 32747 17525 3 1752.891077 585.3048 Ceramide synthase 2 OS=Homo sapiens OX=9606 GN=CERS2 PE=1 SV=1 6.79 3046.1 - 479430 - - - -0.8888 - 2.858 0.453 - 126.2 1 2 0 -0.0016 16 0 0 0 7.02E+06 6.56E+06 - - - 6.2845 0.9997 221125_WJC_METTL3_EV_vs_WT_F03.17530.17530.2 0.00141 13/20 K.LADIQIEQLNR.T "sp|O60925|PFD1_HUMAN,tr|E5RGS4|E5RGS4_HUMAN" 2 1311.7147 1.94 32750 17530 2 1311.713977 656.8646 Prefoldin subunit 1 OS=Homo sapiens OX=9606 GN=PFDN1 PE=1 SV=2 4.37 3046.7 - 8.32E+06 - - - -0.5237 - 2.618 0.246 - 762.1 1 2 0 -0.0007 11 0 0 0 1.01E+08 5.20E+07 - - - 3.4613 0.9999 221125_WJC_METTL3_EV_vs_WT_F03.17531.17531.2 0.00194 17/20 K.LADIQIEQLNR[166.11].T "sp|O60925|PFD1_HUMAN,tr|E5RGS4|E5RGS4_HUMAN" 2 1321.7229 1.94 32751 17531 2 1321.723671 661.8687 Prefoldin subunit 1 OS=Homo sapiens OX=9606 GN=PFDN1 PE=1 SV=2 4.37 3046.8 - 4.69E+06 - - - 0.5576 - 3.044 0.443 - 1502.5 1 2 0 0.0007 11 0 0 0 1.01E+08 5.20E+07 - - - 5.3242 1 221125_WJC_METTL3_EV_vs_WT_F03.17532.17532.3 8.50E-06 17/56 K.EALGGQALYPHVLVK[136.11].N "sp|Q9BUJ2|HNRL1_HUMAN,tr|M0QYZ0|M0QYZ0_HUMAN,tr|A0A0A0MRA5|A0A0A0MRA5_HUMAN,tr|M0R3F1|M0R3F1_HUMAN,tr|B7Z4B8|B7Z4B8_HUMAN" 5 1601.9021 1.54 32752 17532 3 1601.901484 534.9746 Heterogeneous nuclear ribonucleoprotein U-like protein 1 OS=Homo sapiens OX=9606 GN=HNRNPUL1 PE=1 SV=2 6.85 3046.8 - 2.73E+06 - - - -0.3708 - 3.188 0.508 - 416.6 1 2 0 -0.0006 15 0 0 0 5.28E+07 3.43E+07 - - - 7.2288 0.9997 221125_WJC_METTL3_EV_vs_WT_F03.17533.17533.3 5.18E-06 13/60 R.SLETENSALQLQVTER[166.11].E "sp|P20700|LMNB1_HUMAN,tr|A0A0D9SFY5|A0A0D9SFY5_HUMAN,tr|E9PBF6|E9PBF6_HUMAN,tr|A0A0D9SFE5|A0A0D9SFE5_HUMAN" 4 1826.9249 1.11 32753 17533 3 1826.918708 609.9823 Lamin-B1 OS=Homo sapiens OX=9606 GN=LMNB1 PE=1 SV=2 4.25 3046.9 - 2.59E+06 - - - -3.4117 - 2.561 0.438 - 229.4 1 2 0 -0.0062 16 0 0 0 2.72E+07 2.45E+07 - - - 5.8345 0.9997 221125_WJC_METTL3_EV_vs_WT_F03.17535.17535.2 0.000332 20-Nov R.NTVEITELPVR[166.11].T "sp|Q02880|TOP2B_HUMAN,tr|E9PCY5|E9PCY5_HUMAN" 2 1279.7011 1.19 32755 17535 2 1279.699989 640.8578 DNA topoisomerase 2-beta OS=Homo sapiens OX=9606 GN=TOP2B PE=1 SV=3 4.53 3047.1 - 1.47E+06 - - - -0.8963 - 2.425 0.331 - 662.9 1 2 0 -0.0011 11 0 0 0 1.69E+07 1.42E+07 - - - 3.8818 0.9979 221125_WJC_METTL3_EV_vs_WT_F03.17536.17536.2 0.0368 20-Dec R.QGPEGLEVSFR[166.11].G "sp|Q8TDP1|RNH2C_HUMAN,tr|E9PN81|E9PN81_HUMAN" 2 1227.6123 1.17 32756 17536 2 1227.613817 614.8134 Ribonuclease H2 subunit C OS=Homo sapiens OX=9606 GN=RNASEH2C PE=1 SV=1 4.53 3047.2 - 1.42E+06 - - - 1.2186 - 2.055 0.144 - 428.2 1 2 0 0.0015 11 0 0 0 1.84E+07 1.58E+07 - - - 2.0526 0.9997 221125_WJC_METTL3_EV_vs_WT_F03.17537.17537.2 0.017 22-Dec R.LNHLVDSLQQLR.L "sp|P35658|NU214_HUMAN,tr|A0A0A0MSW3|A0A0A0MSW3_HUMAN,tr|A0A494C1F2|A0A494C1F2_HUMAN" 3 1434.7943 3.26 32757 17537 2 1434.792365 718.4044 Nuclear pore complex protein Nup214 OS=Homo sapiens OX=9606 GN=NUP214 PE=1 SV=2 6.74 3047.3 - 948775 - - - -1.357 - 2.119 0.402 - 485.2 1 2 0 -0.0019 12 0 0 0 1.19E+07 3.65E+06 - - - 3.9854 0.967 221125_WJC_METTL3_EV_vs_WT_F03.17538.17538.2 1.08 20-Jun K.LYEPDQLQELK.L "sp|Q9NZB2|F120A_HUMAN,tr|A0A0C4DG79|A0A0C4DG79_HUMAN" 2 1374.7031 2.4 32758 17538 2 1374.703976 688.3588 Constitutive coactivator of PPAR-gamma-like protein 1 OS=Homo sapiens OX=9606 GN=FAM120A PE=1 SV=2 4.14 3047.4 - 728352 - - - 0.6394 - 1.288 0.062 - 63.1 4 2 0 0.0009 11 0 0 0 8.18E+06 3.41E+06 - - - -0.0856 0.9999 221125_WJC_METTL3_EV_vs_WT_F03.17539.17539.3 4.59E-06 18/40 R.TLDELGIHLTK[136.11].E sp|Q15029|U5S1_HUMAN 1 1246.7013 1.8 32759 17539 3 1246.697802 416.5744 116 kDa U5 small nuclear ribonucleoprotein component OS=Homo sapiens OX=9606 GN=EFTUD2 PE=1 SV=1 5.29 3047.6 - 765540 - - - -2.7681 - 2.952 0.494 - 381.9 1 2 0 -0.0035 11 0 0 0 2.66E+07 1.47E+07 - - - 7.1218 0.9835 221125_WJC_METTL3_EV_vs_WT_F03.17540.17540.2 0.000128 16-Oct A.VEDLESVGK.G sp|P81605|DCD_HUMAN 1 974.492 38.28 32760 17540 2 974.489973 488.2533 Dermcidin OS=Homo sapiens OX=9606 GN=DCD PE=1 SV=2 4.14 3047.7 - 579081 - - - -2.1221 - 2.143 0.494 - 316.4 1 1 0 -0.0021 9 0 0 0 6.79E+06 1.77E+05 - - - 4.8941 0.9976 221125_WJC_METTL3_EV_vs_WT_F03.17541.17541.2 0.009 20-Nov K.ANILGLAAGQR.C "sp|Q14807|KIF22_HUMAN,tr|H3BRB3|H3BRB3_HUMAN" 2 1082.6196 1.78 32761 17541 2 1082.623799 542.3171 Kinesin-like protein KIF22 OS=Homo sapiens OX=9606 GN=KIF22 PE=1 SV=5 9.79 3047.8 - 551310 - - - 3.8398 - 2.337 0.312 - 340 1 2 0 0.0042 11 0 0 0 5.76E+06 3.23E+06 - - - 3.6405 0.8726 221125_WJC_METTL3_EV_vs_WT_F03.17546.17546.2 1.77E-05 20-Dec K.DAVEDLESVGK.G sp|P81605|DCD_HUMAN 1 1160.5561 999 32764 17546 2 1162.565447 581.2853 Dermcidin OS=Homo sapiens OX=9606 GN=DCD PE=1 SV=2 3.92 3048.5 - 1.66E+08 - - - 1731.3674 - 2.543 0.499 - 557.7 1 2 0 2.0093 11 0 0 0 2.79E+09 0.00E+00 - - - 4.6206 0.9816 221125_WJC_METTL3_EV_vs_WT_F03.17552.17552.3 0.0026 14/52 K.GFSLLATEDKEALK.K "sp|P09874|PARP1_HUMAN,tr|A0A7I2V5E9|A0A7I2V5E9_HUMAN,tr|A0A7I2V625|A0A7I2V625_HUMAN,tr|A0A7I2V3E1|A0A7I2V3E1_HUMAN" 4 1520.8086 1.28 32770 17552 3 1521.809846 507.9435 Poly [ADP-ribose] polymerase 1 OS=Homo sapiens OX=9606 GN=PARP1 PE=1 SV=4 4.68 3048.8 - 1.92E+06 - - - 658.3484 - 2.759 0.368 - 138.8 1 2 1 1.0012 14 0 0 0 1.49E+07 1.17E+07 - - - 5.0625 1 221125_WJC_METTL3_EV_vs_WT_F03.17554.17554.3 0.000287 17/44 R.GLLSSLDHTSIR.R sp|P08574|CY1_HUMAN 1 1297.699 0.87 32772 17554 3 1297.698849 433.5736 "Cytochrome c1, heme protein, mitochondrial OS=Homo sapiens OX=9606 GN=CYC1 PE=1 SV=3" 6.74 3049.1 - 879248 - - - -0.1271 - 2.969 0.424 - 403.2 1 2 0 -0.0002 12 0 0 0 2.90E+07 3.34E+07 - - - 6.2835 0.9999 221125_WJC_METTL3_EV_vs_WT_F03.17559.17559.2 0.00528 18-Dec K.WTLLQEQGTK.T "sp|P48668|K2C6C_HUMAN,sp|P04259|K2C6B_HUMAN,sp|P13647|K2C5_HUMAN,sp|P02538|K2C6A_HUMAN,tr|F8W0C6|F8W0C6_HUMAN" 5 1202.6295 999 32776 17559 2 1202.629513 602.322 "Keratin, type II cytoskeletal 6C OS=Homo sapiens OX=9606 GN=KRT6C PE=1 SV=3" 6 3049.7 - 6.09E+06 - - - -0.0208 - 2.238 0.515 - 556.3 1 2 0 0 10 0 0 0 9.01E+07 0.00E+00 - - - 5.0934 0.9998 221125_WJC_METTL3_EV_vs_WT_F03.17560.17560.2 0.00233 14-Aug K.SINEFWNK.F "sp|Q9HBM1|SPC25_HUMAN,tr|C9JW94|C9JW94_HUMAN" 2 1036.4978 2.91 32777 17560 2 1036.497571 519.2562 Kinetochore protein Spc25 OS=Homo sapiens OX=9606 GN=SPC25 PE=1 SV=1 5.72 3049.7 - 5.85E+06 - - - -0.2161 - 1.508 0.512 - 164.9 1 2 0 -0.0002 8 0 0 0 5.21E+07 1.79E+07 - - - 4.0615 0.9999 221125_WJC_METTL3_EV_vs_WT_F03.17562.17562.3 0.0175 16/44 R.GLLSSLDHTSIR[166.11].R sp|P08574|CY1_HUMAN 1 1307.7073 0.87 32779 17562 3 1307.706733 436.9097 "Cytochrome c1, heme protein, mitochondrial OS=Homo sapiens OX=9606 GN=CYC1 PE=1 SV=3" 6.74 3049.9 - 1.41E+06 - - - -0.4213 - 3.02 0.376 - 388.1 1 2 0 -0.0006 12 0 0 0 2.90E+07 3.34E+07 - - - 5.7955 0.9999 221125_WJC_METTL3_EV_vs_WT_F03.17563.17563.2 1.34E-07 14/22 K.TGQPMINLYTDR.E "sp|P35637|FUS_HUMAN,tr|H3BPE7|H3BPE7_HUMAN" 2 1407.6816 1 32780 17563 2 1407.681241 704.8481 RNA-binding protein FUS OS=Homo sapiens OX=9606 GN=FUS PE=1 SV=1 5.5 3050 - 1.28E+06 - - - -0.2905 - 2.449 0.57 - 535.1 1 2 0 -0.0004 12 0 0 0 7.49E+08 7.51E+08 - - - 5.6076 0.9879 221125_WJC_METTL3_EV_vs_WT_F03.17564.17564.3 0.0319 Nov-52 K.GFSLLATEDK[136.11]EALK[136.11].K "sp|P09874|PARP1_HUMAN,tr|A0A7I2V5E9|A0A7I2V5E9_HUMAN,tr|A0A7I2V625|A0A7I2V625_HUMAN,tr|A0A7I2V3E1|A0A7I2V3E1_HUMAN" 4 1536.837 1.39 32781 17564 3 1536.833611 513.2863 Poly [ADP-ribose] polymerase 1 OS=Homo sapiens OX=9606 GN=PARP1 PE=1 SV=4 4.68 3050.1 - 1.12E+06 - - - -2.2208 - 2.034 0.244 - 94.2 1 2 1 -0.0034 14 0 0 0 1.72E+07 1.24E+07 - - - 3.1463 0.7754 221125_WJC_METTL3_EV_vs_WT_F03.17567.17567.2 0.17 16-Oct L.QSIFNIGSR[166.11].G "sp|P43243|MATR3_HUMAN,tr|A8MXP9|A8MXP9_HUMAN,tr|D6R991|D6R991_HUMAN,tr|D6REK4|D6REK4_HUMAN,tr|A0A0R4J2E8|A0A0R4J2E8_HUMAN,tr|D6RCM3|D6RCM3_HUMAN,tr|D6R8Z5|D6R8Z5_HUMAN,tr|D6REM6|D6REM6_HUMAN" 8 1030.5435 1.41 32784 17567 2 1030.542535 516.279 Matrin-3 OS=Homo sapiens OX=9606 GN=MATR3 PE=1 SV=2 9.75 3050.5 - 806332 - - - -0.949 - 1.695 0.092 - 360.5 1 1 0 -0.001 9 0 0 0 6.81E+07 4.84E+07 - - - 1.2468 0.9999 221125_WJC_METTL3_EV_vs_WT_F03.17571.17571.2 1.91E-08 28-Dec R.IIEGGIYDADLNDER.V sp|P09228|CYTT_HUMAN 1 1691.8002 2.15 32788 17571 2 1691.801081 846.9074 Cystatin-SA OS=Homo sapiens OX=9606 GN=CST2 PE=1 SV=1 3.77 3051 - 526105 - - - 0.4941 - 2.732 0.543 - 401 1 2 0 0.0008 15 0 0 0 4.35E+06 2.02E+06 - - - 5.5223 0.9997 221125_WJC_METTL3_EV_vs_WT_F03.17572.17572.2 6.23E-05 22-Oct K.WVPVVDPQEEER.R "sp|Q8WUZ0|BCL7C_HUMAN,tr|I3L1Q2|I3L1Q2_HUMAN" 2 1481.7151 2.14 32789 17572 2 1481.716827 741.8648 B-cell CLL\lymphoma 7 protein family member C OS=Homo sapiens OX=9606 GN=BCL7C PE=1 SV=3 4 3051.1 - 519745 - - - 1.1939 - 1.704 0.482 - 292.6 1 2 0 0.0018 12 0 0 0 6.09E+06 2.84E+06 - - - 4.0029 0.9983 221125_WJC_METTL3_EV_vs_WT_F03.17575.17575.3 3.60E-06 15/48 Q.SIVPALEIANAHR.K "sp|P10809|CH60_HUMAN,tr|A0A7I2V2X6|A0A7I2V2X6_HUMAN,tr|A0A7I2YQK6|A0A7I2YQK6_HUMAN,tr|A0A7I2V599|A0A7I2V599_HUMAN,tr|A0A7I2YQ71|A0A7I2YQ71_HUMAN,tr|A0A7I2V5M1|A0A7I2V5M1_HUMAN,tr|A0A7I2V5K3|A0A7I2V5K3_HUMAN,tr|A0A7I2V369|A0A7I2V369_HUMAN" 8 1389.7728 1.38 32791 17575 3 1389.772616 464.2649 "60 kDa heat shock protein, mitochondrial OS=Homo sapiens OX=9606 GN=HSPD1 PE=1 SV=2" 6.47 3051.5 - 3.14E+07 - - - -0.1669 - 2.448 0.579 - 284.6 1 1 0 -0.0002 13 0 0 0 5.42E+08 3.92E+08 - - - 7.4226 0.9998 221125_WJC_METTL3_EV_vs_WT_F03.17579.17579.2 2.86E-05 22-Dec K.TGQPMINLYTDR[166.11].E "sp|P35637|FUS_HUMAN,tr|H3BPE7|H3BPE7_HUMAN" 2 1417.6899 1 32795 17579 2 1417.686857 709.8522 RNA-binding protein FUS OS=Homo sapiens OX=9606 GN=FUS PE=1 SV=1 5.5 3051.6 - 4.26E+06 - - - -2.1606 - 2.608 0.542 - 522.4 1 2 0 -0.0031 12 0 0 0 7.49E+08 7.51E+08 - - - 5.5654 0.9862 221125_WJC_METTL3_EV_vs_WT_F03.17581.17581.2 1.46 14-May K.SINEFWNK[136.11].F "sp|Q9HBM1|SPC25_HUMAN,tr|C9JW94|C9JW94_HUMAN" 2 1044.512 3.07 32797 17581 2 1044.512417 523.2633 Kinetochore protein Spc25 OS=Homo sapiens OX=9606 GN=SPC25 PE=1 SV=1 5.72 3051.8 - 2.11E+06 - - - 0.404 - 1.039 0.174 - 60.7 1 2 0 0.0004 8 0 0 0 5.12E+07 1.67E+07 - - - 0.4414 0.9996 221125_WJC_METTL3_EV_vs_WT_F03.17582.17582.2 0.0853 18-Oct K.DIEIDALSQK.C "sp|Q15643|TRIPB_HUMAN,tr|H0YJ97|H0YJ97_HUMAN" 2 1130.5819 0.16 32798 17582 2 1130.582015 566.2982 Thyroid receptor-interacting protein 11 OS=Homo sapiens OX=9606 GN=TRIP11 PE=1 SV=3 4.03 3051.8 - 1.81E+06 - - - 0.0849 - 1.855 0.327 - 270.4 1 2 0 0.0001 10 0 0 0 2.10E+07 1.34E+08 - - - 3.1809 0.9866 221125_WJC_METTL3_EV_vs_WT_F03.17583.17583.2 0.00526 28-Oct K.AEPVSSTEASSLGQK[136.11].D sp|Q7Z2K8|GRIN1_HUMAN 1 1497.7402 0.1 32799 17583 2 1497.747637 749.8774 G protein-regulated inducer of neurite outgrowth 1 OS=Homo sapiens OX=9606 GN=GPRIN1 PE=1 SV=2 4.53 3051.9 - 1.15E+06 - - - 4.9541 - 1.72 0.313 - 232.6 1 2 0 0.0074 15 0 0 0 1.27E+06 1.27E+07 - - - 2.6838 0.9998 221125_WJC_METTL3_EV_vs_WT_F03.17585.17585.2 4.23E-07 13/28 R.QTGEGVGPQEYTLLK.L "sp|Q9P2J5|SYLC_HUMAN,tr|A0A6I8PIV1|A0A6I8PIV1_HUMAN,tr|A0A6I8PRS0|A0A6I8PRS0_HUMAN,tr|A0A6I8PLB8|A0A6I8PLB8_HUMAN,tr|A0A6I8PIP7|A0A6I8PIP7_HUMAN,tr|A0A6I8PIT3|A0A6I8PIT3_HUMAN,tr|A0A6I8PTV8|A0A6I8PTV8_HUMAN,tr|A0A6I8PRU9|A0A6I8PRU9_HUMAN,tr|A0A6I8PS05|A0A6I8PS05_HUMAN,tr|B4DER1|B4DER1_HUMAN,tr|A0A6I8PL42|A0A6I8PL42_HUMAN" 11 1618.8203 1.1 32801 17585 2 1618.817802 810.4174 "Leucine--tRNA ligase, cytoplasmic OS=Homo sapiens OX=9606 GN=LARS1 PE=1 SV=2" 4.53 3052.2 - 831575 - - - -1.5134 - 2.154 0.556 - 324 1 2 0 -0.0024 15 0 0 0 1.65E+07 1.49E+07 - - - 5.0334 0.836 221125_WJC_METTL3_EV_vs_WT_F03.17587.17587.2 0.00228 20-Oct K.AMTGVEQWPYR[166.11].A "sp|P49368|TCPG_HUMAN,tr|B4DUR8|B4DUR8_HUMAN" 2 1346.6317 0.04 32803 17587 2 1347.628141 674.3231 T-complex protein 1 subunit gamma OS=Homo sapiens OX=9606 GN=CCT3 PE=1 SV=4 6.05 3052.5 - 510058 - - - 739.9685 - 2.054 0.437 - 407.6 1 2 0 0.9965 11 0 0 0 7.87E+06 2.06E+08 - - - 3.903 0.9931 221125_WJC_METTL3_EV_vs_WT_F03.17588.17588.3 0.0679 Jul-36 K.K[136.11]ADEVLEILK[136.11].T "sp|O75643|U520_HUMAN,tr|A0A494C1A5|A0A494C1A5_HUMAN" 2 1172.6987 5.18 32804 17588 3 1172.696495 391.9069 U5 small nuclear ribonucleoprotein 200 kDa helicase OS=Homo sapiens OX=9606 GN=SNRNP200 PE=1 SV=2 4.68 3052.6 - 368029 - - - -1.9144 - 1.547 0.229 - 57.2 1 2 0 -0.0022 10 0 0 0 1.91E+07 3.69E+06 - - - 2.3667 0.9999 221125_WJC_METTL3_EV_vs_WT_F03.17589.17589.2 1.19E-08 15/28 R.GENLVSMTVEGPPPK[136.11].D "sp|P63162|RSMN_HUMAN,sp|P14678|RSMB_HUMAN,tr|J3QLE5|J3QLE5_HUMAN" 3 1561.7901 2.09 32805 17589 2 1561.788784 781.9023 Small nuclear ribonucleoprotein-associated protein N OS=Homo sapiens OX=9606 GN=SNRPN PE=1 SV=1 4.53 3052.7 - 295951 - - - -0.8708 - 2.698 0.572 - 863.7 1 2 0 -0.0014 15 0 0 0 1.42E+07 6.81E+06 - - - 5.7055 0.9987 221125_WJC_METTL3_EV_vs_WT_F03.17595.17595.2 0.00109 14-Sep R.C[160.03]EDIC[160.03]WIK[136.11].T "sp|Q9HCE5|MET14_HUMAN,tr|D6RBL4|D6RBL4_HUMAN" 2 1130.498 0.03 32809 17595 2 1130.500411 566.2563 N6-adenosine-methyltransferase non-catalytic subunit OS=Homo sapiens OX=9606 GN=METTL14 PE=1 SV=2 4.37 3053.4 - 2.63E+06 - - - 2.1309 - 1.629 0.335 - 216.1 1 2 0 0.0024 8 0 0 0 9.63E+05 3.21E+07 - - - 2.9862 0.995 221125_WJC_METTL3_EV_vs_WT_F03.17597.17597.2 5.41E-05 22-Dec K.VAPPAVLNDISK.K "sp|Q9Y520|PRC2C_HUMAN,tr|E7EPN9|E7EPN9_HUMAN,tr|H7C5N8|H7C5N8_HUMAN,tr|A0A2R8Y7F4|A0A2R8Y7F4_HUMAN,tr|A0A2R8YET2|A0A2R8YET2_HUMAN" 5 1222.6921 2.01 32811 17597 2 1222.699243 612.3533 Protein PRRC2C OS=Homo sapiens OX=9606 GN=PRRC2C PE=1 SV=4 5.81 3053.5 - 2.68E+06 - - - 5.8109 - 2.363 0.44 - 403 1 2 0 0.0071 12 0 0 0 4.70E+07 2.34E+07 - - - 4.5512 0.9999 221125_WJC_METTL3_EV_vs_WT_F03.17598.17598.2 0.000529 18-Oct K.SADTLWGIQK.E sp|P00338|LDHA_HUMAN 1 1117.5768 0.95 32812 17598 2 1117.576457 559.7957 L-lactate dehydrogenase A chain OS=Homo sapiens OX=9606 GN=LDHA PE=1 SV=2 5.55 3053.6 - 1.71E+06 - - - -0.2836 - 2.32 0.448 - 356.5 1 2 0 -0.0003 10 0 0 0 2.97E+07 3.13E+07 - - - 4.6989 0.9999 221125_WJC_METTL3_EV_vs_WT_F03.17602.17602.2 5.39E-06 14/22 K.QLQDIATLADQR.R sp|O95373|IPO7_HUMAN 1 1370.7154 2.41 32816 17602 2 1370.716417 686.365 Importin-7 OS=Homo sapiens OX=9606 GN=IPO7 PE=1 SV=1 4.21 3054.1 - 907222 - - - 0.7471 - 2.579 0.447 - 748.5 1 2 0 0.001 12 0 0 0 2.31E+07 9.56E+06 - - - 4.835 0.9785 221125_WJC_METTL3_EV_vs_WT_F03.17608.17608.2 1.95E-07 14/26 R.C[160.03]GPEPTEVFTVGPK[136.11].T "sp|Q6NZ36|FAP20_HUMAN,tr|H7C361|H7C361_HUMAN,tr|H7C2E6|H7C2E6_HUMAN,tr|H7C3A6|H7C3A6_HUMAN" 4 1524.7374 3.68 32822 17608 2 1525.735501 763.376 Fanconi anemia core complex-associated protein 20 OS=Homo sapiens OX=9606 GN=FAAP20 PE=1 SV=2 4.53 3054.8 - 260571 - - - 654.6183 - 2.583 0.601 - 632.6 1 2 0 0.9981 14 0 0 0 1.94E+07 5.27E+06 - - - 5.5479 0.9999 221125_WJC_METTL3_EV_vs_WT_F03.17609.17609.2 1.44E-06 24-Oct K.EYWNDPELDEGER.F "sp|Q8N9T8|KRI1_HUMAN,tr|F8WFC1|F8WFC1_HUMAN,tr|H0YFD2|H0YFD2_HUMAN,tr|A0A494C108|A0A494C108_HUMAN" 4 1650.6798 1.37 32823 17609 2 1650.681983 826.3472 Protein KRI1 homolog OS=Homo sapiens OX=9606 GN=KRI1 PE=1 SV=3 3.77 3055 - 291637 - - - 1.3255 - 2.182 0.587 - 238.9 1 2 0 0.0022 13 0 0 0 2.94E+06 2.15E+06 - - - 5.3784 0.9997 221125_WJC_METTL3_EV_vs_WT_F03.17613.17613.2 0.000944 14-Jul R.EFADFEYR[166.11].K "sp|Q8ND56|LS14A_HUMAN,tr|A0A140TA66|A0A140TA66_HUMAN,tr|A0A096LP11|A0A096LP11_HUMAN,tr|A0A0G2JQ95|A0A0G2JQ95_HUMAN" 4 1085.4693 1 32825 17613 2 1085.470728 543.7419 Protein LSM14 homolog A OS=Homo sapiens OX=9606 GN=LSM14A PE=1 SV=3 4.14 3055.6 - 1.11E+06 - - - 1.2741 - 1.601 0.472 - 264.8 1 2 0 0.0014 8 0 0 0 5.52E+07 5.52E+07 - - - 3.9462 0.9572 221125_WJC_METTL3_EV_vs_WT_F03.17615.17615.2 0.00699 16-Aug Q.DGVESLLQK[136.11].F "sp|Q86U44|MTA70_HUMAN,tr|B4E349|B4E349_HUMAN,tr|F5H6D8|F5H6D8_HUMAN,tr|H0YFV6|H0YFV6_HUMAN,tr|B4DTN4|B4DTN4_HUMAN" 5 995.5379 0.01 32827 17615 2 995.538581 498.7762 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 4.37 3055.7 - 3.46E+06 - - - 0.7082 - 1.841 0.268 - 201.5 1 1 0 0.0007 9 0 0 0 2.06E+05 4.07E+07 - - - 2.7859 0.9999 221125_WJC_METTL3_EV_vs_WT_F03.17616.17616.3 8.12E-05 17/48 K.IQELFHVEPGLQR.L "sp|Q96T88|UHRF1_HUMAN,tr|A0A087WTW0|A0A087WTW0_HUMAN,tr|A0A087WVR3|A0A087WVR3_HUMAN" 3 1564.8362 1.13 32828 17616 3 1564.838604 522.6193 E3 ubiquitin-protein ligase UHRF1 OS=Homo sapiens OX=9606 GN=UHRF1 PE=1 SV=1 5.4 3055.7 - 1.61E+06 - - - 1.551 - 2.925 0.344 - 414.9 1 2 0 0.0024 13 0 0 0 1.86E+07 1.65E+07 - - - 5.2846 0.9999 221125_WJC_METTL3_EV_vs_WT_F03.17617.17617.3 0.00011 19/48 K.IQELFHVEPGLQR[166.11].L "sp|Q96T88|UHRF1_HUMAN,tr|A0A087WTW0|A0A087WTW0_HUMAN,tr|A0A087WVR3|A0A087WVR3_HUMAN" 3 1574.8444 1.16 32829 17617 3 1574.846383 525.9554 E3 ubiquitin-protein ligase UHRF1 OS=Homo sapiens OX=9606 GN=UHRF1 PE=1 SV=1 5.4 3055.8 - 1.05E+06 - - - 1.2293 - 3.355 0.34 - 606.4 1 2 0 0.0019 13 0 0 0 1.90E+07 1.65E+07 - - - 5.612 0.9986 221125_WJC_METTL3_EV_vs_WT_F03.17618.17618.3 5.40E-05 Nov-44 K.LTLHGLQQYYVK[136.11].L "sp|Q13838|DX39B_HUMAN,sp|O00148|DX39A_HUMAN,tr|A0A140TA18|A0A140TA18_HUMAN,tr|F6UJC5|F6UJC5_HUMAN,tr|H0Y400|H0Y400_HUMAN,tr|F6WLT2|F6WLT2_HUMAN,tr|Q5STU3|Q5STU3_HUMAN,tr|A0A140T9X9|A0A140T9X9_HUMAN,tr|A0A140T996|A0A140T996_HUMAN,tr|A0A0G2JJZ9|A0A0G2JJZ9_HUMAN,tr|A0A140T9X3|A0A140T9X3_HUMAN,tr|H0YCC6|H0YCC6_HUMAN" 12 1469.8122 0.97 32830 17618 3 1469.813683 490.9447 Spliceosome RNA helicase DDX39B OS=Homo sapiens OX=9606 GN=DDX39B PE=1 SV=1 8.5 3055.9 - 997163 - - - 1.009 - 2.156 0.221 - 120.9 1 2 0 0.0015 12 0 0 0 9.00E+07 9.23E+07 - - - 3.133 0.9999 221125_WJC_METTL3_EV_vs_WT_F03.17620.17620.3 0.0079 15/40 R.IVALNAHTFLR[166.11].N "sp|P22087|FBRL_HUMAN,sp|A6NHQ2|FBLL1_HUMAN,tr|M0R299|M0R299_HUMAN,tr|M0R0P1|M0R0P1_HUMAN,tr|M0QXL5|M0QXL5_HUMAN,tr|M0R2Q4|M0R2Q4_HUMAN" 6 1263.7327 0.72 32832 17620 3 1263.733874 422.2515 rRNA 2'-O-methyltransferase fibrillarin OS=Homo sapiens OX=9606 GN=FBL PE=1 SV=2 9.76 3056.2 - 887569 - - - 0.9203 - 3.033 0.369 - 427.2 1 2 0 0.0012 11 0 0 0 1.21E+07 1.67E+07 - - - 5.8057 0.9998 221125_WJC_METTL3_EV_vs_WT_F03.17621.17621.3 0.000339 15/44 K.LTLHGLQQYYVK.L "sp|Q13838|DX39B_HUMAN,sp|O00148|DX39A_HUMAN,tr|A0A140TA18|A0A140TA18_HUMAN,tr|F6UJC5|F6UJC5_HUMAN,tr|H0Y400|H0Y400_HUMAN,tr|F6WLT2|F6WLT2_HUMAN,tr|Q5STU3|Q5STU3_HUMAN,tr|A0A140T9X9|A0A140T9X9_HUMAN,tr|A0A140T996|A0A140T996_HUMAN,tr|A0A0G2JJZ9|A0A0G2JJZ9_HUMAN,tr|A0A140T9X3|A0A140T9X3_HUMAN,tr|H0YCC6|H0YCC6_HUMAN" 12 1461.798 0.97 32833 17621 3 1461.798391 488.2733 Spliceosome RNA helicase DDX39B OS=Homo sapiens OX=9606 GN=DDX39B PE=1 SV=1 8.5 3056.3 - 861829 - - - 0.2675 - 2.443 0.339 - 244 1 2 0 0.0004 12 0 0 0 9.00E+07 9.23E+07 - - - 4.7953 1 221125_WJC_METTL3_EV_vs_WT_F03.17623.17623.3 0.000106 16/40 R.IVALNAHTFLR.N "sp|P22087|FBRL_HUMAN,sp|A6NHQ2|FBLL1_HUMAN,tr|M0R299|M0R299_HUMAN,tr|M0R0P1|M0R0P1_HUMAN,tr|M0QXL5|M0QXL5_HUMAN,tr|M0R2Q4|M0R2Q4_HUMAN" 6 1253.7244 0.72 32835 17623 3 1253.724884 418.9154 rRNA 2'-O-methyltransferase fibrillarin OS=Homo sapiens OX=9606 GN=FBL PE=1 SV=2 9.76 3056.6 - 805160 - - - 0.3533 - 3.167 0.443 - 543.9 1 2 0 0.0004 11 0 0 0 1.21E+07 1.67E+07 - - - 6.7538 0.9867 221125_WJC_METTL3_EV_vs_WT_F03.17624.17624.3 0.224 Sep-40 K.ADLYIHVTYIK[136.11].K sp|Q9NX62|IMPA3_HUMAN 1 1342.7376 2.43 32836 17624 3 1342.734609 448.5865 "Golgi-resident adenosine 3',5'-bisphosphate 3'-phosphatase OS=Homo sapiens OX=9606 GN=BPNT2 PE=1 SV=1" 6.79 3056.6 - 778045 - - - -2.2558 - 1.885 0.158 - 116.7 1 2 0 -0.003 11 0 0 0 3.19E+07 1.31E+07 - - - 2.1016 1 221125_WJC_METTL3_EV_vs_WT_F03.17625.17625.2 3.74E-07 17/26 R.GLLASDLNTDGDMR[166.11].V "sp|Q86YP4|P66A_HUMAN,tr|V9GY85|V9GY85_HUMAN,tr|V9GYX5|V9GYX5_HUMAN,tr|C9JJK9|C9JJK9_HUMAN,tr|H7C3H1|H7C3H1_HUMAN,tr|C9JVY3|C9JVY3_HUMAN,tr|C9JMI3|C9JMI3_HUMAN,tr|C9JGN4|C9JGN4_HUMAN" 8 1486.6961 0.71 32837 17625 2 1486.697076 744.3553 Transcriptional repressor p66-alpha OS=Homo sapiens OX=9606 GN=GATAD2A PE=1 SV=1 3.93 3056.8 - 769732 - - - 0.6383 - 3.198 0.625 - 1172.1 1 2 0 0.0009 14 0 0 0 6.97E+06 9.77E+06 - - - 6.5743 0.9999 221125_WJC_METTL3_EV_vs_WT_F03.17627.17627.2 1.41E-06 20-Dec R.DANLYVSGLPK.T "sp|Q12926|ELAV2_HUMAN,sp|P26378|ELAV4_HUMAN,sp|Q14576|ELAV3_HUMAN,tr|B1AM48|B1AM48_HUMAN,tr|A0A494C0F8|A0A494C0F8_HUMAN,tr|A0A494C147|A0A494C147_HUMAN,tr|A0A494C015|A0A494C015_HUMAN,tr|A0A494C1D9|A0A494C1D9_HUMAN,tr|A0A0R4J2E6|A0A0R4J2E6_HUMAN,tr|A0A494C173|A0A494C173_HUMAN,tr|A0A0A0MRX1|A0A0A0MRX1_HUMAN,tr|B1APY9|B1APY9_HUMAN" 12 1175.6186 0.96 32838 17627 2 1175.619915 588.8166 ELAV-like protein 2 OS=Homo sapiens OX=9606 GN=ELAVL2 PE=1 SV=2 5.83 3057 - 1.37E+06 - - - 1.0854 - 2.659 0.529 - 578.2 1 2 0 0.0013 11 0 0 0 1.65E+07 1.73E+07 - - - 5.5934 0.9133 221125_WJC_METTL3_EV_vs_WT_F03.17629.17629.2 8.91 20-Jun K.QGGFLGLSNIK.F "sp|P15941|MUC1_HUMAN,tr|A0A087WVJ0|A0A087WVJ0_HUMAN,tr|A0A0C4DGW3|A0A0C4DGW3_HUMAN,tr|A0A0A0MSH4|A0A0A0MSH4_HUMAN,tr|A0A087WWM1|A0A087WWM1_HUMAN,tr|A0A087X061|A0A087X061_HUMAN,tr|A0A087X2A4|A0A087X2A4_HUMAN,tr|A0A0A0MRB3|A0A0A0MRB3_HUMAN,tr|B1AVQ7|B1AVQ7_HUMAN,tr|A0A087WZZ6|A0A087WZZ6_HUMAN,tr|Q7Z536|Q7Z536_HUMAN" 11 1132.6241 999 32839 17629 2 1132.626096 567.3193 Mucin-1 OS=Homo sapiens OX=9606 GN=MUC1 PE=1 SV=3 8.75 3057.2 - 4.04E+06 - - - 1.7994 - 1.094 0.103 - 85.9 8 2 0 0.002 11 0 0 0 6.23E+07 0.00E+00 - - - -0.3593 0.9998 221125_WJC_METTL3_EV_vs_WT_F03.17632.17632.2 4.15E-05 22-Nov K.TVSLPLSSPNIK.L "sp|Q8IWZ3|ANKH1_HUMAN,tr|A0A0A0MQZ8|A0A0A0MQZ8_HUMAN,tr|H0Y472|H0Y472_HUMAN,tr|H0Y7Y3|H0Y7Y3_HUMAN,tr|H0Y4P6|H0Y4P6_HUMAN,tr|H0Y785|H0Y785_HUMAN" 6 1254.7184 1.35 32842 17632 2 1254.719581 628.3665 Ankyrin repeat and KH domain-containing protein 1 OS=Homo sapiens OX=9606 GN=ANKHD1 PE=1 SV=1 8.41 3057.4 - 1.47E+06 - - - 0.9787 - 2.112 0.479 - 322.7 1 2 0 0.0012 12 0 0 0 1.88E+08 1.40E+08 - - - 4.5457 0.9999 221125_WJC_METTL3_EV_vs_WT_F03.17634.17634.2 3.30E-07 18-Nov R.GC[160.03]AFVTFTTR[166.11].A "sp|Q92879|CELF1_HUMAN,tr|G5EA30|G5EA30_HUMAN" 2 1168.5574 106.73 32844 17634 2 1168.558555 585.286 CUGBP Elav-like family member 1 OS=Homo sapiens OX=9606 GN=CELF1 PE=1 SV=2 8.25 3057.6 - 1.17E+06 - - - 0.9465 - 2.261 0.559 - 684.6 1 2 0 0.0011 10 0 0 0 1.12E+09 1.05E+07 - - - 5.4466 0.9996 221125_WJC_METTL3_EV_vs_WT_F03.17635.17635.2 6.89E-06 13/22 K.TVSLPLSSPNIK[136.11].L "sp|Q8IWZ3|ANKH1_HUMAN,tr|A0A0A0MQZ8|A0A0A0MQZ8_HUMAN,tr|H0Y472|H0Y472_HUMAN,tr|H0Y7Y3|H0Y7Y3_HUMAN,tr|H0Y4P6|H0Y4P6_HUMAN,tr|H0Y785|H0Y785_HUMAN" 6 1262.7326 1.35 32845 17635 2 1262.735832 632.3736 Ankyrin repeat and KH domain-containing protein 1 OS=Homo sapiens OX=9606 GN=ANKHD1 PE=1 SV=1 8.41 3057.7 - 1.10E+06 - - - 2.5967 - 2.241 0.508 - 501.6 1 2 0 0.0033 12 0 0 0 1.88E+08 1.40E+08 - - - 4.9152 0.9997 221125_WJC_METTL3_EV_vs_WT_F03.17636.17636.2 0.000671 22-Dec K.VAPPAVLNDISK[136.11].K "sp|Q9Y520|PRC2C_HUMAN,tr|E7EPN9|E7EPN9_HUMAN,tr|H7C5N8|H7C5N8_HUMAN,tr|A0A2R8Y7F4|A0A2R8Y7F4_HUMAN,tr|A0A2R8YET2|A0A2R8YET2_HUMAN" 5 1230.7063 2.01 32846 17636 2 1230.707555 616.3604 Protein PRRC2C OS=Homo sapiens OX=9606 GN=PRRC2C PE=1 SV=4 5.81 3057.8 - 989960 - - - 0.9889 - 2.3 0.359 - 439.2 1 2 0 0.0012 12 0 0 0 4.70E+07 2.34E+07 - - - 3.8837 0.9999 221125_WJC_METTL3_EV_vs_WT_F03.17638.17638.3 0.031 13/44 K.LALDMEINAYRK.L sp|Q03252|LMNB2_HUMAN 1 1435.7493 0.98 32848 17638 3 1435.749474 479.5904 Lamin-B2 OS=Homo sapiens OX=9606 GN=LMNB2 PE=1 SV=4 6.07 3058 - 696667 - - - 0.0968 - 2.547 0.349 - 259.9 1 2 0 0.0001 12 0 0 0 6.95E+06 7.11E+06 - - - 5.0224 0.9999 221125_WJC_METTL3_EV_vs_WT_F03.17640.17640.3 0.000996 15/36 R.TSFLDDAFR[166.11]K[136.11].N "sp|Q14204|DYHC1_HUMAN,tr|A0A7P0T8N2|A0A7P0T8N2_HUMAN,tr|A0A7P0T9C4|A0A7P0T9C4_HUMAN,tr|A0A7P0TBJ7|A0A7P0TBJ7_HUMAN,tr|A0A7P0T9K2|A0A7P0T9K2_HUMAN,tr|A0A2R8Y706|A0A2R8Y706_HUMAN,tr|A0A7P0T916|A0A7P0T916_HUMAN,tr|A0A7P0TB75|A0A7P0TB75_HUMAN,tr|A0A7P0T8W5|A0A7P0T8W5_HUMAN,tr|A0A7P0TAF3|A0A7P0TAF3_HUMAN,tr|A0A7P0T9F1|A0A7P0T9F1_HUMAN,tr|A0A7P0TAW9|A0A7P0TAW9_HUMAN,tr|A0A7P0TA13|A0A7P0TA13_HUMAN,tr|A0A7P0T7V5|A0A7P0T7V5_HUMAN,tr|A0A7P0T9R4|A0A7P0T9R4_HUMAN,tr|A0A2R8Y5T0|A0A2R8Y5T0_HUMAN,tr|A0A2R8YFZ7|A0A2R8YFZ7_HUMAN,tr|A0A2R8Y6H2|A0A2R8Y6H2_HUMAN" 18 1216.6207 0.85 32850 17640 3 1216.619479 406.5475 Cytoplasmic dynein 1 heavy chain 1 OS=Homo sapiens OX=9606 GN=DYNC1H1 PE=1 SV=5 5.63 3058.3 - 456911 - - - -1.0102 - 2.325 0.411 - 352.9 1 2 0 -0.0012 10 0 0 0 3.90E+06 4.56E+06 - - - 5.5859 0.9998 221125_WJC_METTL3_EV_vs_WT_F03.17643.17643.3 0.000411 Nov-40 R.FGEIVDIDIKK.V "sp|Q96T58|MINT_HUMAN,tr|H0Y5U7|H0Y5U7_HUMAN,tr|A0A669KB49|A0A669KB49_HUMAN" 3 1275.7075 1.28 32853 17643 3 1275.709406 426.2431 Msx2-interacting protein OS=Homo sapiens OX=9606 GN=SPEN PE=1 SV=1 4.56 3058.7 - 281920 - - - 1.5301 - 2.072 0.401 - 117.6 1 2 0 0.002 11 0 0 0 2.64E+06 2.07E+06 - - - 5.0798 0.9999 221125_WJC_METTL3_EV_vs_WT_F03.17646.17646.3 0.000186 14/36 K.STFVLDEFK[136.11]R[166.11].K sp|P26641|EF1G_HUMAN 1 1258.6677 0.88 32854 17646 3 1258.667406 420.5632 Elongation factor 1-gamma OS=Homo sapiens OX=9606 GN=EEF1G PE=1 SV=3 5.79 3059.1 - 4.68E+06 - - - -0.2002 - 2.308 0.428 - 341.5 1 2 0 -0.0003 10 0 0 0 1.57E+08 1.79E+08 - - - 5.7543 0.9998 221125_WJC_METTL3_EV_vs_WT_F03.17647.17647.2 0.000394 16-Aug R.QQMFEFDTK.T "sp|Q9Y5K5|UCHL5_HUMAN,tr|H0Y4E0|H0Y4E0_HUMAN,tr|Q5LJA9|Q5LJA9_HUMAN,tr|H0Y6Y4|H0Y6Y4_HUMAN,tr|Q5LJB0|Q5LJB0_HUMAN,tr|Q5LJA5|Q5LJA5_HUMAN" 6 1172.5172 1.6 32855 17647 2 1172.517748 587.2659 Ubiquitin carboxyl-terminal hydrolase isozyme L5 OS=Homo sapiens OX=9606 GN=UCHL5 PE=1 SV=3 4.37 3059.1 - 2.59E+06 - - - 0.4588 - 1.788 0.478 - 273.1 1 2 0 0.0005 9 0 0 0 1.19E+08 7.46E+07 - - - 4.2525 0.9998 221125_WJC_METTL3_EV_vs_WT_F03.17648.17648.2 0.000288 14-Jul R.EFADFEYR.K "sp|Q8ND56|LS14A_HUMAN,tr|A0A140TA66|A0A140TA66_HUMAN,tr|A0A096LP11|A0A096LP11_HUMAN,tr|A0A0G2JQ95|A0A0G2JQ95_HUMAN" 4 1075.4611 1 32856 17648 2 1075.461986 538.7378 Protein LSM14 homolog A OS=Homo sapiens OX=9606 GN=LSM14A PE=1 SV=3 4.14 3059.2 - 4.81E+06 - - - 0.8471 - 1.583 0.502 - 231.6 1 2 0 0.0009 8 0 0 0 5.52E+07 5.52E+07 - - - 4.1338 0.9999 221125_WJC_METTL3_EV_vs_WT_F03.17649.17649.3 0.0889 13/36 K.STFVLDEFKR.K sp|P26641|EF1G_HUMAN 1 1240.6452 0.88 32857 17649 3 1240.645639 414.5557 Elongation factor 1-gamma OS=Homo sapiens OX=9606 GN=EEF1G PE=1 SV=3 5.79 3059.3 - 2.55E+06 - - - 0.3635 - 2.423 0.334 - 289.2 1 2 0 0.0005 10 0 0 0 1.57E+08 1.79E+08 - - - 4.8483 0.9988 221125_WJC_METTL3_EV_vs_WT_F03.17650.17650.3 0.0473 Aug-40 K.ADLYIHVTYIK.K sp|Q9NX62|IMPA3_HUMAN 1 1334.7234 1.96 32858 17650 3 1334.724271 445.9151 "Golgi-resident adenosine 3',5'-bisphosphate 3'-phosphatase OS=Homo sapiens OX=9606 GN=BPNT2 PE=1 SV=1" 6.79 3059.3 - 2.26E+06 - - - 0.6241 - 1.814 0.262 - 92 1 2 0 0.0008 11 0 0 0 2.60E+07 1.33E+07 - - - 3.1526 0.9998 221125_WJC_METTL3_EV_vs_WT_F03.17651.17651.2 0.000181 16-Jul R.QQMFEFDTK[136.11].T "sp|Q9Y5K5|UCHL5_HUMAN,tr|H0Y4E0|H0Y4E0_HUMAN,tr|Q5LJA9|Q5LJA9_HUMAN,tr|H0Y6Y4|H0Y6Y4_HUMAN,tr|Q5LJB0|Q5LJB0_HUMAN,tr|Q5LJA5|Q5LJA5_HUMAN" 6 1180.5314 1.62 32859 17651 2 1180.530053 591.273 Ubiquitin carboxyl-terminal hydrolase isozyme L5 OS=Homo sapiens OX=9606 GN=UCHL5 PE=1 SV=3 4.37 3059.4 - 2.17E+06 - - - -1.1495 - 1.72 0.542 - 227.1 1 2 0 -0.0014 9 0 0 0 1.19E+08 7.35E+07 - - - 4.6128 0.9998 221125_WJC_METTL3_EV_vs_WT_F03.17653.17653.2 0.00149 20-Dec K.VLC[160.03]ELADLQDK[136.11].E "sp|P17987|TCPA_HUMAN,tr|F5H726|F5H726_HUMAN,tr|F5H136|F5H136_HUMAN,tr|F5GZI8|F5GZI8_HUMAN,tr|E7ERF2|E7ERF2_HUMAN,tr|F5H676|F5H676_HUMAN" 6 1310.6632 0.32 32861 17653 2 1310.661768 656.3389 T-complex protein 1 subunit alpha OS=Homo sapiens OX=9606 GN=TCP1 PE=1 SV=1 4.03 3059.6 - 1.58E+06 - - - -1.0567 - 2.299 0.449 - 581.4 1 2 0 -0.0014 11 0 0 0 4.75E+06 1.47E+07 - - - 4.6089 0.9975 221125_WJC_METTL3_EV_vs_WT_F03.17654.17654.2 0.00389 20-Jul R.SLGLQLPDGQR[166.11].R sp|O15067|PUR4_HUMAN 1 1192.644 1.14 32862 17654 2 1192.646669 597.3293 Phosphoribosylformylglycinamidine synthase OS=Homo sapiens OX=9606 GN=PFAS PE=1 SV=4 5.55 3059.6 - 1.26E+06 - - - 2.2748 - 1.799 0.246 - 150.4 1 2 0 0.0027 11 0 0 0 2.07E+07 1.81E+07 - - - 2.4457 1 221125_WJC_METTL3_EV_vs_WT_F03.17656.17656.2 1.49E-06 14/28 K.GVPVSEAEC[160.03]TAMGLR.S "sp|Q5VT66|MARC1_HUMAN,sp|Q969Z3|MARC2_HUMAN,tr|F6V6Z1|F6V6Z1_HUMAN,tr|A0A494C1P3|A0A494C1P3_HUMAN" 4 1575.7385 1.78 32864 17656 2 1575.746537 788.8765 Mitochondrial amidoxime-reducing component 1 OS=Homo sapiens OX=9606 GN=MTARC1 PE=1 SV=1 4.53 3059.9 - 1.12E+06 - - - 5.0922 - 2.589 0.617 - 428.2 1 2 0 0.008 15 0 0 0 1.39E+07 7.78E+06 - - - 5.9344 0.9999 221125_WJC_METTL3_EV_vs_WT_F03.17657.17657.2 1.61E-07 13/24 K.GLGTGTLYIAESR.L "sp|P54105|ICLN_HUMAN,tr|E9PJF4|E9PJF4_HUMAN,tr|J3KN38|J3KN38_HUMAN,tr|E9PMI6|E9PMI6_HUMAN" 4 1336.6987 1.17 32865 17657 2 1336.699263 669.3566 Methylosome subunit pICln OS=Homo sapiens OX=9606 GN=CLNS1A PE=1 SV=1 6 3060 - 1.11E+06 - - - 0.4361 - 2.598 0.546 - 699.4 1 2 0 0.0006 13 0 0 0 1.10E+07 9.48E+06 - - - 5.5239 0.9988 221125_WJC_METTL3_EV_vs_WT_F03.17658.17658.2 1.34E-06 28-Sep K.FSPNGEWLASSSADK.L "sp|P61964|WDR5_HUMAN,tr|V9GZ59|V9GZ59_HUMAN" 2 1594.7264 1.51 32866 17658 2 1594.732525 798.3705 WD repeat-containing protein 5 OS=Homo sapiens OX=9606 GN=WDR5 PE=1 SV=1 4.37 3060.1 - 975637 - - - 3.8715 - 2.114 0.501 - 244.7 1 2 0 0.0062 15 0 0 0 1.82E+07 1.21E+07 - - - 4.5799 0.9998 221125_WJC_METTL3_EV_vs_WT_F03.17659.17659.3 0.000517 Dec-36 R.TSFLDDAFRK.N "sp|Q14204|DYHC1_HUMAN,tr|A0A7P0T8N2|A0A7P0T8N2_HUMAN,tr|A0A7P0T9C4|A0A7P0T9C4_HUMAN,tr|A0A7P0TBJ7|A0A7P0TBJ7_HUMAN,tr|A0A7P0T9K2|A0A7P0T9K2_HUMAN,tr|A0A2R8Y706|A0A2R8Y706_HUMAN,tr|A0A7P0T916|A0A7P0T916_HUMAN,tr|A0A7P0TB75|A0A7P0TB75_HUMAN,tr|A0A7P0T8W5|A0A7P0T8W5_HUMAN,tr|A0A7P0TAF3|A0A7P0TAF3_HUMAN,tr|A0A7P0T9F1|A0A7P0T9F1_HUMAN,tr|A0A7P0TAW9|A0A7P0TAW9_HUMAN,tr|A0A7P0TA13|A0A7P0TA13_HUMAN,tr|A0A7P0T7V5|A0A7P0T7V5_HUMAN,tr|A0A7P0T9R4|A0A7P0T9R4_HUMAN,tr|A0A2R8Y5T0|A0A2R8Y5T0_HUMAN,tr|A0A2R8YFZ7|A0A2R8YFZ7_HUMAN,tr|A0A2R8Y6H2|A0A2R8Y6H2_HUMAN" 18 1198.5982 0.85 32867 17659 3 1198.599078 400.54 Cytoplasmic dynein 1 heavy chain 1 OS=Homo sapiens OX=9606 GN=DYNC1H1 PE=1 SV=5 5.63 3060.2 - 631576 - - - 0.7008 - 2.059 0.344 - 193.8 1 2 0 0.0008 10 0 0 0 3.90E+06 4.56E+06 - - - 4.4842 0.9999 221125_WJC_METTL3_EV_vs_WT_F03.17660.17660.3 0.000426 13/36 R.TLFGLHLSQK[136.11].R "sp|P31939|PUR9_HUMAN,tr|H7C1S2|H7C1S2_HUMAN" 2 1150.659 0.81 32868 17660 3 1150.658921 384.5603 Bifunctional purine biosynthesis protein ATIC OS=Homo sapiens OX=9606 GN=ATIC PE=1 SV=3 8.44 3060.4 - 630627 - - - -0.0634 - 2.158 0.453 - 213.2 1 2 0 -0.0001 10 0 0 0 3.97E+06 4.91E+06 - - - 5.8368 1 221125_WJC_METTL3_EV_vs_WT_F03.17661.17661.2 2.09E-06 15/28 K.FSPNGEWLASSSADK[136.11].L "sp|P61964|WDR5_HUMAN,tr|V9GZ59|V9GZ59_HUMAN" 2 1602.7406 1.51 32869 17661 2 1602.737102 802.3776 WD repeat-containing protein 5 OS=Homo sapiens OX=9606 GN=WDR5 PE=1 SV=1 4.37 3060.5 - 564965 - - - -2.1519 - 2.883 0.592 - 914.3 1 2 0 -0.0034 15 0 0 0 1.82E+07 1.21E+07 - - - 6.0156 0.9988 221125_WJC_METTL3_EV_vs_WT_F03.17662.17662.3 0.154 18/44 K.WIGLDLSNGKPR.D "sp|P17987|TCPA_HUMAN,tr|F5H282|F5H282_HUMAN,tr|E7EQR6|E7EQR6_HUMAN" 3 1354.7357 0.4 32870 17662 3 1354.738881 452.5859 T-complex protein 1 subunit alpha OS=Homo sapiens OX=9606 GN=TCP1 PE=1 SV=1 8.75 3060.6 - 515743 - - - 2.323 - 2.984 0.204 - 599.2 1 2 0 0.0031 12 0 0 0 1.72E+08 4.27E+08 - - - 3.8439 1 221125_WJC_METTL3_EV_vs_WT_F03.17665.17665.2 2.58E-10 14/34 R.SAAEMYGSVTEHPSPSPL.L "sp|P07910|HNRPC_HUMAN,tr|G3V575|G3V575_HUMAN,tr|B4DSU6|B4DSU6_HUMAN,tr|G3V576|G3V576_HUMAN,tr|G3V555|G3V555_HUMAN,tr|G3V2Q1|G3V2Q1_HUMAN" 6 1858.8407 - 32873 17665 2 1858.840282 930.4276 Heterogeneous nuclear ribonucleoproteins C1\C2 OS=Homo sapiens OX=9606 GN=HNRNPC PE=1 SV=4 4.51 3061 - 301888 - - - -0.2405 - 2.902 0.653 - 617.2 1 1 0 -0.0004 18 0 0 0 - - - - - 6.4833 0.991 221125_WJC_METTL3_EV_vs_WT_F03.17667.17667.3 4.76E-05 Nov-48 Q.SIVPALEIANAHR[166.11].K "sp|P10809|CH60_HUMAN,tr|A0A7I2V2X6|A0A7I2V2X6_HUMAN,tr|A0A7I2YQK6|A0A7I2YQK6_HUMAN,tr|A0A7I2V599|A0A7I2V599_HUMAN,tr|A0A7I2YQ71|A0A7I2YQ71_HUMAN,tr|A0A7I2V5M1|A0A7I2V5M1_HUMAN,tr|A0A7I2V5K3|A0A7I2V5K3_HUMAN,tr|A0A7I2V369|A0A7I2V369_HUMAN" 8 1399.7811 1.38 32874 17667 3 1399.781887 467.601 "60 kDa heat shock protein, mitochondrial OS=Homo sapiens OX=9606 GN=HSPD1 PE=1 SV=2" 6.47 3061.3 - 1.40E+06 - - - 0.5494 - 2.469 0.39 - 150 1 1 0 0.0008 13 0 0 0 5.42E+08 3.92E+08 - - - 5.3384 1 221125_WJC_METTL3_EV_vs_WT_F03.17669.17669.3 6.58E-12 24/80 R.VTGEADVEFATHEDAVAAMSK.D "sp|P31943|HNRH1_HUMAN,tr|H0YBD7|H0YBD7_HUMAN,tr|H0YB39|H0YB39_HUMAN,tr|H0YBG7|H0YBG7_HUMAN,tr|E9PCY7|E9PCY7_HUMAN,tr|G8JLB6|G8JLB6_HUMAN" 6 2176.9947 1.16 32875 17669 3 2176.994636 726.6722 Heterogeneous nuclear ribonucleoprotein H OS=Homo sapiens OX=9606 GN=HNRNPH1 PE=1 SV=4 4.17 3061.5 - 1.79E+06 - - - -0.0129 - 5.092 0.694 - 662 1 2 0 0 21 0 0 0 2.22E+07 1.90E+07 - - - 10.1797 1 221125_WJC_METTL3_EV_vs_WT_F03.17670.17670.2 8.08E-11 15/28 K.TGGYLTESGYVNLQR[166.11].V sp|Q9H0D6|XRN2_HUMAN 1 1666.819 1.95 32876 17670 2 1666.819389 834.4168 5'-3' exoribonuclease 2 OS=Homo sapiens OX=9606 GN=XRN2 PE=1 SV=1 5.66 3061.6 - 1.53E+06 - - - 0.2214 - 3.014 0.571 - 728.2 1 2 0 0.0004 15 0 0 0 6.47E+07 3.32E+07 - - - 5.9707 0.9999 221125_WJC_METTL3_EV_vs_WT_F03.17671.17671.2 2.49E-06 18-Nov K.STFVLDEFKR.K sp|P26641|EF1G_HUMAN 1 1240.6452 1.16 32877 17671 2 1240.643894 621.3299 Elongation factor 1-gamma OS=Homo sapiens OX=9606 GN=EEF1G PE=1 SV=3 5.79 3061.7 - 1.80E+06 - - - -1.043 - 2.165 0.557 - 464.1 1 2 0 -0.0013 10 0 0 0 4.14E+07 3.57E+07 - - - 5.3107 1 221125_WJC_METTL3_EV_vs_WT_F03.17672.17672.2 1.59E-07 14/22 R.GLC[160.03]AIAQAESLR[166.11].Y "sp|P23396|RS3_HUMAN,tr|F2Z2S8|F2Z2S8_HUMAN,tr|H0YCJ7|H0YCJ7_HUMAN,tr|H0YF32|H0YF32_HUMAN" 4 1297.6688 0.59 32878 17672 2 1297.667365 649.8417 40S ribosomal protein S3 OS=Homo sapiens OX=9606 GN=RPS3 PE=1 SV=2 5.99 3061.8 - 1.76E+06 - - - -1.0989 - 2.936 0.572 - 746.3 1 2 0 -0.0014 12 0 0 0 1.62E+07 2.74E+07 - - - 6.0992 0.997 221125_WJC_METTL3_EV_vs_WT_F03.17673.17673.2 9.53E-05 20-Oct K.GYTLVEYETYK.E "sp|Q9Y5S9|RBM8A_HUMAN,tr|A0A0J9YW13|A0A0J9YW13_HUMAN" 2 1364.65 3.7 32879 17673 2 1364.656781 683.3323 RNA-binding protein 8A OS=Homo sapiens OX=9606 GN=RBM8A PE=1 SV=1 4.53 3061.9 - 1.56E+06 - - - 4.9705 - 2.035 0.471 - 386.1 1 2 0 0.0068 11 0 0 0 2.73E+07 7.38E+06 - - - 4.4397 0.9998 221125_WJC_METTL3_EV_vs_WT_F03.17675.17675.3 0.00465 16/56 K.TPGYVVTPHTMNLLK.Q "sp|P47897|SYQ_HUMAN,tr|B4DDN1|B4DDN1_HUMAN,tr|C9J165|C9J165_HUMAN,tr|A0A0U1RQT0|A0A0U1RQT0_HUMAN,tr|A0A1B0GVU9|A0A1B0GVU9_HUMAN,tr|A0A0U1RR66|A0A0U1RR66_HUMAN" 6 1669.8862 1.63 32881 17675 3 1669.889063 557.636 Glutamine--tRNA ligase OS=Homo sapiens OX=9606 GN=QARS1 PE=1 SV=1 8.29 3062.1 - 1.42E+06 - - - 1.7366 - 2.612 0.377 - 247.1 1 2 0 0.0029 15 0 0 0 1.51E+07 9.23E+06 - - - 5.2477 1 221125_WJC_METTL3_EV_vs_WT_F03.17677.17677.3 5.72E-07 13/56 K.TGGYLTESGYVNLQR.V sp|Q9H0D6|XRN2_HUMAN 1 1656.8108 1.96 32883 17677 3 1656.810153 553.2775 5'-3' exoribonuclease 2 OS=Homo sapiens OX=9606 GN=XRN2 PE=1 SV=1 5.66 3062.2 - 1.09E+06 - - - -0.3603 - 2.363 0.504 - 180.7 1 2 0 -0.0006 15 0 0 0 1.79E+07 9.13E+06 - - - 6.4028 0.7985 221125_WJC_METTL3_EV_vs_WT_F03.17678.17678.3 0.0287 Aug-40 K.EFKAELILYR[166.11]K.S "sp|Q9ULD8|KCNH3_HUMAN,tr|A0A3B3ITH0|A0A3B3ITH0_HUMAN" 2 1418.8161 - 32884 17678 3 1418.827618 473.946 Potassium voltage-gated channel subfamily H member 3 OS=Homo sapiens OX=9606 GN=KCNH3 PE=1 SV=2 8.59 3062.3 - 1.03E+06 - - - 8.1138 - 1.846 0.306 - 50.3 1 2 1 0.0115 11 0 0 0 - - - - - 3.6899 0.9911 221125_WJC_METTL3_EV_vs_WT_F03.17680.17680.3 0.000107 Sep-40 K.FAAQELIEVK[136.11]R[166.11].G "sp|Q86U44|MTA70_HUMAN,tr|F5H6D8|F5H6D8_HUMAN,tr|H0YFV6|H0YFV6_HUMAN,tr|B4DTN4|B4DTN4_HUMAN" 4 1320.7521 0.04 32886 17680 3 1320.75123 441.258 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 6.14 3062.6 - 484160 - - - -0.6254 - 1.795 0.15 - 86.4 1 2 0 -0.0008 11 0 0 0 1.56E+05 4.41E+06 - - - 1.874 0.9997 221125_WJC_METTL3_EV_vs_WT_F03.17685.17685.3 0.0153 18/56 K.VGEVIVTK[136.11]DDAMLLK[136.11].G "sp|P10809|CH60_HUMAN,tr|A0A7I2V2X6|A0A7I2V2X6_HUMAN,tr|A0A7I2YQK6|A0A7I2YQK6_HUMAN,tr|A0A7I2V599|A0A7I2V599_HUMAN" 4 1645.9295 1.17 32889 17685 3 1645.931864 549.6505 "60 kDa heat shock protein, mitochondrial OS=Homo sapiens OX=9606 GN=HSPD1 PE=1 SV=2" 4.56 3063.2 - 3.77E+06 - - - 1.4089 - 2.946 0.421 - 439.2 1 2 1 0.0023 15 0 0 0 1.15E+09 9.78E+08 - - - 6.0524 1 221125_WJC_METTL3_EV_vs_WT_F03.17686.17686.2 0.000168 13/24 R.DMFASVGADGSVR.M "sp|P61962|DCAF7_HUMAN,tr|A0A087WWI6|A0A087WWI6_HUMAN" 2 1310.5925 1.2 32890 17686 2 1310.593584 656.3035 DDB1- and CUL4-associated factor 7 OS=Homo sapiens OX=9606 GN=DCAF7 PE=1 SV=1 4.21 3063.3 - 2.46E+06 - - - 0.8271 - 2.635 0.603 - 650.6 1 2 0 0.0011 13 0 0 0 6.99E+07 5.84E+07 - - - 5.9811 0.9998 221125_WJC_METTL3_EV_vs_WT_F03.17687.17687.2 0.0437 16-Sep R.VLDELTLAR.A "sp|Q04695|K1C17_HUMAN,sp|P02533|K1C14_HUMAN,sp|P08727|K1C19_HUMAN,sp|P08779|K1C16_HUMAN,sp|P19012|K1C15_HUMAN,tr|K7EPJ9|K7EPJ9_HUMAN,tr|C9JM50|C9JM50_HUMAN,tr|C9JTG5|C9JTG5_HUMAN,tr|F5GWP8|F5GWP8_HUMAN,tr|K7EMS3|K7EMS3_HUMAN,tr|A8MT21|A8MT21_HUMAN" 11 1028.5866 50.62 32891 17687 2 1028.587026 515.3006 "Keratin, type I cytoskeletal 17 OS=Homo sapiens OX=9606 GN=KRT17 PE=1 SV=2" 4.37 3063.3 - 3.41E+06 - - - 0.4044 - 2.009 0.381 - 290.5 1 2 0 0.0004 9 0 0 0 4.65E+07 9.19E+05 - - - 3.8732 0.9961 221125_WJC_METTL3_EV_vs_WT_F03.17692.17692.3 4.72E-06 14/40 E.SLTEELAYLKK.N "sp|P13645|K1C10_HUMAN,tr|A0A1B0GVI3|A0A1B0GVI3_HUMAN" 2 1293.718 281.34 32896 17692 3 1293.717927 432.2466 "Keratin, type I cytoskeletal 10 OS=Homo sapiens OX=9606 GN=KRT10 PE=1 SV=6" 5.86 3063.8 - 1.29E+06 - - - -0.0703 - 2.494 0.457 - 206.3 1 1 0 -0.0001 11 0 0 0 7.04E+07 2.50E+05 - - - 6.2313 0.9984 221125_WJC_METTL3_EV_vs_WT_F03.17693.17693.2 0.0395 13/22 K.LLDLVQQSC[160.03]NYK[136.11].Q "sp|P55769|NH2L1_HUMAN,tr|B1AHD1|B1AHD1_HUMAN,tr|A0A3B3IUA2|A0A3B3IUA2_HUMAN" 3 1487.7534 0.82 32897 17693 2 1487.758279 744.884 NHP2-like protein 1 OS=Homo sapiens OX=9606 GN=SNU13 PE=1 SV=3 5.83 3063.9 - 1.17E+06 - - - 3.303 - 2.14 0.358 - 624.6 1 2 0 0.0049 12 0 0 0 1.27E+08 1.55E+08 - - - 3.6855 0.9962 221125_WJC_METTL3_EV_vs_WT_F03.17694.17694.3 0.0068 13/56 K.TPGYVVTPHTMNLLK[136.11].Q "sp|P47897|SYQ_HUMAN,tr|B4DDN1|B4DDN1_HUMAN,tr|C9J165|C9J165_HUMAN,tr|A0A0U1RQT0|A0A0U1RQT0_HUMAN,tr|A0A1B0GVU9|A0A1B0GVU9_HUMAN,tr|A0A0U1RR66|A0A0U1RR66_HUMAN" 6 1677.9004 1.69 32898 17694 3 1677.908679 560.3074 Glutamine--tRNA ligase OS=Homo sapiens OX=9606 GN=QARS1 PE=1 SV=1 8.29 3063.9 - 1.12E+06 - - - 4.9562 - 2.53 0.31 - 255.1 1 2 0 0.0083 15 0 0 0 1.47E+07 8.74E+06 - - - 4.416 0.9999 221125_WJC_METTL3_EV_vs_WT_F03.17696.17696.3 0.000651 Nov-36 K.LTSMHFYGWK[136.11].Q "sp|P23921|RIR1_HUMAN,tr|E9PL69|E9PL69_HUMAN" 2 1276.6154 0.25 32900 17696 3 1276.616382 426.5457 Ribonucleoside-diphosphate reductase large subunit OS=Homo sapiens OX=9606 GN=RRM1 PE=1 SV=1 8.6 3064.1 - 683665 - - - 0.7583 - 2.122 0.457 - 139.4 1 2 0 0.001 10 0 0 0 2.06E+06 8.15E+06 - - - 5.832 0.9997 221125_WJC_METTL3_EV_vs_WT_F03.17697.17697.2 0.000452 Oct-32 K.VVQNDAYTAPALPSSIR.T "sp|Q9BY77|PDIP3_HUMAN,tr|F6VRR5|F6VRR5_HUMAN,tr|F8WCX5|F8WCX5_HUMAN,tr|Q8WUT1|Q8WUT1_HUMAN" 4 1800.937 4.48 32901 17697 2 1800.940646 901.4758 Polymerase delta-interacting protein 3 OS=Homo sapiens OX=9606 GN=POLDIP3 PE=1 SV=2 5.81 3064.3 - 495365 - - - 2.0173 - 2.136 0.494 - 214.9 1 2 0 0.0036 17 0 0 0 2.87E+06 6.41E+05 - - - 4.5544 0.9997 221125_WJC_METTL3_EV_vs_WT_F03.17698.17698.2 0.00399 26-Sep R.QFIEMVNGTDSEVR.C sp|Q96S59|RANB9_HUMAN 1 1623.7563 1.22 32902 17698 2 1623.753881 812.8854 Ran-binding protein 9 OS=Homo sapiens OX=9606 GN=RANBP9 PE=1 SV=1 4.14 3064.4 - 433021 - - - -1.4719 - 1.99 0.444 - 222.7 1 2 0 -0.0024 14 0 0 0 4.17E+06 3.43E+06 - - - 4.0465 0.9992 221125_WJC_METTL3_EV_vs_WT_F03.17699.17699.3 0.0328 Oct-32 R.EYYLLHLQR.W "sp|P78318|IGBP1_HUMAN,tr|A0A1W2PR95|A0A1W2PR95_HUMAN" 2 1233.6506 0.48 32903 17699 3 1233.653496 412.2241 Immunoglobulin-binding protein 1 OS=Homo sapiens OX=9606 GN=IGBP1 PE=1 SV=1 6.85 3064.5 - 367400 - - - 2.3418 - 1.938 0.321 - 168.5 1 2 0 0.0029 9 0 0 0 8.42E+06 1.75E+07 - - - 4.1121 0.9999 221125_WJC_METTL3_EV_vs_WT_F03.17704.17704.3 3.15E-05 19/56 K.VGEVIVTKDDAMLLK.G "sp|P10809|CH60_HUMAN,tr|A0A7I2V2X6|A0A7I2V2X6_HUMAN,tr|A0A7I2YQK6|A0A7I2YQK6_HUMAN,tr|A0A7I2V599|A0A7I2V599_HUMAN" 4 1629.9011 1.17 32906 17704 3 1629.901215 544.3077 "60 kDa heat shock protein, mitochondrial OS=Homo sapiens OX=9606 GN=HSPD1 PE=1 SV=2" 4.56 3065.1 - 2.18E+07 - - - 0.0429 - 3.494 0.493 - 570.8 1 2 1 0.0001 15 0 0 0 1.15E+09 9.78E+08 - - - 7.3009 1 221125_WJC_METTL3_EV_vs_WT_F03.17705.17705.3 2.74E-06 Nov-56 R.SVYFKPSLTPSGEFR.K sp|P49790|NU153_HUMAN 1 1713.8726 1.25 32907 17705 3 1713.873704 572.2982 Nuclear pore complex protein Nup153 OS=Homo sapiens OX=9606 GN=NUP153 PE=1 SV=2 8.31 3065.1 - 4.28E+06 - - - 0.6313 - 2.273 0.517 - 122.3 1 2 0 0.0011 15 0 0 0 5.59E+07 4.47E+07 - - - 6.4463 0.9963 221125_WJC_METTL3_EV_vs_WT_F03.17706.17706.2 0.163 20-Jun K.SAYNSYSWGAN.- "sp|Q14157|UBP2L_HUMAN,tr|H0Y5H6|H0Y5H6_HUMAN" 2 1218.4942 - 32908 17706 2 1218.494765 610.2544 Ubiquitin-associated protein 2-like OS=Homo sapiens OX=9606 GN=UBAP2L PE=1 SV=2 5.24 3065.2 - 5.24E+06 - - - 0.4916 - 1.08 0.288 - 82.4 1 2 0 0.0006 11 0 0 0 - - - - - 1.3762 1 221125_WJC_METTL3_EV_vs_WT_F03.17708.17708.2 3.34E-06 13/22 K.LLDLVQQSC[160.03]NYK.Q "sp|P55769|NH2L1_HUMAN,tr|B1AHD1|B1AHD1_HUMAN,tr|A0A3B3IUA2|A0A3B3IUA2_HUMAN" 3 1479.7392 0.86 32910 17708 2 1479.739561 740.8769 NHP2-like protein 1 OS=Homo sapiens OX=9606 GN=SNU13 PE=1 SV=3 5.83 3065.3 - 2.60E+06 - - - 0.2676 - 2.604 0.589 - 577.5 1 2 0 0.0004 12 0 0 0 1.27E+08 1.47E+08 - - - 5.9094 0.9999 221125_WJC_METTL3_EV_vs_WT_F03.17709.17709.3 9.43E-06 15/48 K.VLTPEEQLADK[136.11]LR[166.11].L sp|O75822|EIF3J_HUMAN 1 1528.858 1.08 32911 17709 3 1528.857592 510.6266 Eukaryotic translation initiation factor 3 subunit J OS=Homo sapiens OX=9606 GN=EIF3J PE=1 SV=2 4.68 3065.4 - 2.01E+06 - - - -0.2525 - 2.932 0.518 - 383.2 1 2 1 -0.0004 13 0 0 0 2.11E+07 1.96E+07 - - - 7.2316 1 221125_WJC_METTL3_EV_vs_WT_F03.17711.17711.2 2.57E-05 19/28 K.VGEVIVTK[136.11]DDAMLLK[136.11].G "sp|P10809|CH60_HUMAN,tr|A0A7I2V2X6|A0A7I2V2X6_HUMAN,tr|A0A7I2YQK6|A0A7I2YQK6_HUMAN,tr|A0A7I2V599|A0A7I2V599_HUMAN" 4 1645.9295 1.14 32913 17711 2 1645.930203 823.972 "60 kDa heat shock protein, mitochondrial OS=Homo sapiens OX=9606 GN=HSPD1 PE=1 SV=2" 4.56 3065.6 - 1.89E+06 - - - 0.3998 - 3.614 0.547 - 1099.5 1 2 1 0.0007 15 0 0 0 8.85E+07 7.74E+07 - - - 6.2397 0.7934 221125_WJC_METTL3_EV_vs_WT_F03.17712.17712.3 2.73 Oct-40 K.SNLELFK[136.11]EELK[136.11].Q "sp|O15042|SR140_HUMAN,tr|E7EW00|E7EW00_HUMAN,tr|E7ET15|E7ET15_HUMAN,tr|H0Y8D9|H0Y8D9_HUMAN" 4 1364.7522 0.65 32914 17712 3 1364.748883 455.9247 U2 snRNP-associated SURP motif-containing protein OS=Homo sapiens OX=9606 GN=U2SURP PE=1 SV=2 4.78 3065.6 - 1.61E+06 - - - -2.4539 - 2.228 0.059 - 165.1 2 2 1 -0.0033 11 0 0 0 7.65E+06 1.18E+07 - - - 1.3333 0.9999 221125_WJC_METTL3_EV_vs_WT_F03.17713.17713.2 0.000227 13/22 K.WIGLDLSNGKPR.D "sp|P17987|TCPA_HUMAN,tr|F5H282|F5H282_HUMAN,tr|E7EQR6|E7EQR6_HUMAN" 3 1354.7357 0.43 32915 17713 2 1354.735664 678.3751 T-complex protein 1 subunit alpha OS=Homo sapiens OX=9606 GN=TCP1 PE=1 SV=1 8.75 3065.8 - 1.50E+06 - - - -0.0517 - 2.508 0.426 - 578.6 1 2 0 -0.0001 12 0 0 0 1.62E+07 3.76E+07 - - - 4.6067 1 221125_WJC_METTL3_EV_vs_WT_F03.17714.17714.2 1.96E-05 22/28 K.VGEVIVTKDDAMLLK.G "sp|P10809|CH60_HUMAN,tr|A0A7I2V2X6|A0A7I2V2X6_HUMAN,tr|A0A7I2YQK6|A0A7I2YQK6_HUMAN,tr|A0A7I2V599|A0A7I2V599_HUMAN" 4 1629.9011 1.14 32916 17714 2 1629.900188 815.9578 "60 kDa heat shock protein, mitochondrial OS=Homo sapiens OX=9606 GN=HSPD1 PE=1 SV=2" 4.56 3065.9 - 1.37E+06 - - - -0.5872 - 4.164 0.592 - 1613.3 1 2 1 -0.001 15 0 0 0 8.85E+07 7.74E+07 - - - 6.9203 0.9805 221125_WJC_METTL3_EV_vs_WT_F03.17715.17715.2 0.0337 12-Aug K.K[136.11]WYTIFK[136.11].D sp|Q9BZL1|UBL5_HUMAN 1 1000.5717 1.91 32917 17715 2 1000.576529 501.2931 Ubiquitin-like protein 5 OS=Homo sapiens OX=9606 GN=UBL5 PE=1 SV=1 9.7 3066 - 983119 - - - 4.8372 - 1.48 0.269 - 207.5 1 2 0 0.0048 7 0 0 0 1.69E+07 8.87E+06 - - - 2.2685 0.9944 221125_WJC_METTL3_EV_vs_WT_F03.17716.17716.2 4.55E-05 24-Dec K.FNVEDGEIVQQVR.V sp|Q8N766|EMC1_HUMAN 1 1531.7631 1.22 32918 17716 2 1531.754683 766.8888 ER membrane protein complex subunit 1 OS=Homo sapiens OX=9606 GN=EMC1 PE=1 SV=1 4.14 3066.1 - 871819 - - - -5.476 - 2.057 0.424 - 351.2 1 2 0 -0.0084 13 0 0 0 6.05E+06 4.97E+06 - - - 4.0211 0.9999 221125_WJC_METTL3_EV_vs_WT_F03.17717.17717.3 0.000104 Dec-40 K.LTLLHYDPVVK[136.11].Q sp|O75394|RM33_HUMAN 1 1304.7584 1.05 32919 17717 3 1304.757283 435.9267 "39S ribosomal protein L33, mitochondrial OS=Homo sapiens OX=9606 GN=MRPL33 PE=1 SV=1" 6.74 3066.2 - 803651 - - - -0.8362 - 2.306 0.439 - 279 1 2 0 -0.0011 11 0 0 0 1.20E+07 1.15E+07 - - - 5.8077 0.9995 221125_WJC_METTL3_EV_vs_WT_F03.17718.17718.3 0.0206 Dec-44 R.LAAGPTFQHFLK.S sp|Q96SZ6|CK5P1_HUMAN 1 1328.7241 0.65 32920 17718 3 1328.723772 443.9153 Mitochondrial tRNA methylthiotransferase CDK5RAP1 OS=Homo sapiens OX=9606 GN=CDK5RAP1 PE=1 SV=2 8.76 3066.4 - 544489 - - - -0.2521 - 2.004 0.296 - 128.3 1 2 0 -0.0003 12 0 0 0 7.00E+06 1.08E+07 - - - 3.7669 0.8171 221125_WJC_METTL3_EV_vs_WT_F03.17719.17719.3 2.48 Jul-36 K.LTSMHFYGWK.Q "sp|P23921|RIR1_HUMAN,tr|E9PL69|E9PL69_HUMAN" 2 1268.6012 0.26 32921 17719 3 1268.598841 423.8743 Ribonucleoside-diphosphate reductase large subunit OS=Homo sapiens OX=9606 GN=RRM1 PE=1 SV=1 8.6 3066.5 - 362906 - - - -1.8706 - 1.21 0.124 - 52.4 2 2 0 -0.0024 10 0 0 0 2.06E+06 8.04E+06 - - - 0.3392 0.9999 221125_WJC_METTL3_EV_vs_WT_F03.17721.17721.3 1.27E-06 14/48 K.VLTPEEQLADKLR.L sp|O75822|EIF3J_HUMAN 1 1510.8355 1.09 32922 17721 3 1510.834647 504.6191 Eukaryotic translation initiation factor 3 subunit J OS=Homo sapiens OX=9606 GN=EIF3J PE=1 SV=2 4.68 3066.8 - 2.51E+06 - - - -0.5699 - 2.668 0.475 - 284.3 1 2 1 -0.0009 13 0 0 0 2.06E+07 1.89E+07 - - - 6.4962 1 221125_WJC_METTL3_EV_vs_WT_F03.17723.17723.2 1.75E-05 14/26 K.GPVEGYEENEEFLR.T sp|Q9UI30|TR112_HUMAN 1 1666.7475 1.41 32923 17723 2 1666.744059 834.381 Multifunctional methyltransferase subunit TRM112-like protein OS=Homo sapiens OX=9606 GN=TRMT112 PE=1 SV=1 3.98 3067 - 3.70E+06 - - - -2.0531 - 2.576 0.601 - 649.6 1 2 0 -0.0034 14 0 0 0 3.20E+08 2.27E+08 - - - 5.8534 1 221125_WJC_METTL3_EV_vs_WT_F03.17724.17724.2 8.60E-06 14/26 K.GPVEGYEENEEFLR[166.11].T sp|Q9UI30|TR112_HUMAN 1 1676.7558 1.41 32924 17724 2 1676.753696 839.3852 Multifunctional methyltransferase subunit TRM112-like protein OS=Homo sapiens OX=9606 GN=TRMT112 PE=1 SV=1 3.98 3067 - 2.98E+06 - - - -1.2256 - 2.845 0.612 - 562.7 1 2 0 -0.0021 14 0 0 0 3.20E+08 2.27E+08 - - - 6.1844 0.8438 221125_WJC_METTL3_EV_vs_WT_F03.17725.17725.2 0.000893 20-Oct K.DAVEDLESVGK.G sp|P81605|DCD_HUMAN 1 1160.5561 303.6 32925 17725 2 1161.564114 581.2853 Dermcidin OS=Homo sapiens OX=9606 GN=DCD PE=1 SV=2 3.92 3067.1 - 3.05E+06 - - - 868.5629 - 1.943 0.348 - 414.6 1 2 0 1.008 11 0 0 0 4.91E+07 1.62E+05 - - - 3.0917 0.9993 221125_WJC_METTL3_EV_vs_WT_F03.17726.17726.3 0.000409 Nov-44 K.SPYQEFTDHLVK.T "sp|P15880|RS2_HUMAN,tr|E9PQD7|E9PQD7_HUMAN,tr|H0YEN5|H0YEN5_HUMAN" 3 1462.7092 0.99 32926 17726 3 1462.709532 488.577 40S ribosomal protein S2 OS=Homo sapiens OX=9606 GN=RPS2 PE=1 SV=2 5.3 3067.1 - 2.24E+06 - - - 0.1962 - 2.02 0.274 - 136.5 1 2 0 0.0003 12 0 0 0 8.81E+07 8.93E+07 - - - 3.5436 0.8191 221125_WJC_METTL3_EV_vs_WT_F03.17727.17727.3 6.05 Jul-40 K.TYLQALPYFDR.L "sp|O75306|NDUS2_HUMAN,tr|A0A7I2V4X8|A0A7I2V4X8_HUMAN,tr|A0A7I2V4G5|A0A7I2V4G5_HUMAN,tr|A0A7I2V5D5|A0A7I2V5D5_HUMAN,tr|A0A7I2YQG7|A0A7I2YQG7_HUMAN,tr|A0A7I2V596|A0A7I2V596_HUMAN,tr|A0A7I2V5G4|A0A7I2V5G4_HUMAN,tr|A0A7I2V410|A0A7I2V410_HUMAN,tr|A0A7I2V630|A0A7I2V630_HUMAN,tr|A0A7I2V2B9|A0A7I2V2B9_HUMAN,tr|A0A7I2YQD8|A0A7I2YQD8_HUMAN,tr|A0A7I2V517|A0A7I2V517_HUMAN,tr|A0A7I2V3J6|A0A7I2V3J6_HUMAN,tr|A0A7I2V5E2|A0A7I2V5E2_HUMAN,tr|A0A7I2V4W5|A0A7I2V4W5_HUMAN" 15 1385.698 1.9 32927 17727 3 1385.696359 462.9066 "NADH dehydrogenase [ubiquinone] iron-sulfur protein 2, mitochondrial OS=Homo sapiens OX=9606 GN=NDUFS2 PE=1 SV=2" 5.5 3067.2 - 2.18E+06 - - - -1.1496 - 1.242 0.111 - 30.2 4 2 0 -0.0016 11 0 0 0 1.58E+07 8.34E+06 - - - 0.1141 0.9949 221125_WJC_METTL3_EV_vs_WT_F03.17728.17728.3 0.0833 Jul-44 K.SPYQEFTDHLVK[136.11].T "sp|P15880|RS2_HUMAN,tr|E9PQD7|E9PQD7_HUMAN,tr|H0YEN5|H0YEN5_HUMAN" 3 1470.7234 1.02 32928 17728 3 1470.723883 491.2484 40S ribosomal protein S2 OS=Homo sapiens OX=9606 GN=RPS2 PE=1 SV=2 5.3 3067.3 - 2.12E+06 - - - 0.2978 - 1.641 0.207 - 51.2 1 2 0 0.0004 12 0 0 0 2.90E+08 2.85E+08 - - - 2.2206 1 221125_WJC_METTL3_EV_vs_WT_F03.17731.17731.3 8.07E-08 17/48 R.RPQIDPAVEGFIR.D "sp|Q8WU79|SMAP2_HUMAN,tr|A0A087WV97|A0A087WV97_HUMAN,tr|X6RCC3|X6RCC3_HUMAN" 3 1496.81 1.74 32931 17731 3 1496.808953 499.9439 Stromal membrane-associated protein 2 OS=Homo sapiens OX=9606 GN=SMAP2 PE=1 SV=1 6.07 3067.5 - 1.16E+06 - - - -0.6741 - 3.572 0.563 - 525 1 2 0 -0.001 13 0 0 0 9.22E+07 5.30E+07 - - - 8.2684 1 221125_WJC_METTL3_EV_vs_WT_F03.17732.17732.2 1.40E-09 21/26 V.GEVIVTKDDAMLLK.G "sp|P10809|CH60_HUMAN,tr|A0A7I2V2X6|A0A7I2V2X6_HUMAN,tr|A0A7I2YQK6|A0A7I2YQK6_HUMAN,tr|A0A7I2V599|A0A7I2V599_HUMAN" 4 1530.8327 2 32932 17732 2 1530.832698 766.4236 "60 kDa heat shock protein, mitochondrial OS=Homo sapiens OX=9606 GN=HSPD1 PE=1 SV=2" 4.56 3067.7 - 1.06E+06 - - - -0.0216 - 3.846 0.607 - 1340.9 1 1 1 0 14 0 0 0 1.90E+07 9.49E+06 - - - 6.9046 0.9997 221125_WJC_METTL3_EV_vs_WT_F03.17733.17733.2 8.46E-05 24-Sep K.YSPPAISPLVSEK[136.11].Q sp|Q14694|UBP10_HUMAN 1 1394.7537 1.39 32933 17733 2 1394.753045 698.3841 Ubiquitin carboxyl-terminal hydrolase 10 OS=Homo sapiens OX=9606 GN=USP10 PE=1 SV=2 6 3067.8 - 910812 - - - -0.4567 - 1.865 0.413 - 143.7 1 2 0 -0.0006 13 0 0 0 8.99E+06 6.45E+06 - - - 3.6908 0.9999 221125_WJC_METTL3_EV_vs_WT_F03.17735.17735.2 6.78E-08 22-Nov R.ESNYFGLSPEER[166.11].R sp|Q01804|OTUD4_HUMAN 1 1436.6447 1.55 32935 17735 2 1436.644032 719.3296 OTU domain-containing protein 4 OS=Homo sapiens OX=9606 GN=OTUD4 PE=1 SV=4 4.25 3068 - 683281 - - - -0.4956 - 1.995 0.579 - 389.6 1 2 0 -0.0007 12 0 0 0 1.13E+07 7.29E+06 - - - 5.1345 1 221125_WJC_METTL3_EV_vs_WT_F03.17737.17737.2 3.19E-09 14/32 K.IEELDQENEAALENGIK[136.11].N "sp|P43243|MATR3_HUMAN,tr|B3KM87|B3KM87_HUMAN,tr|A8MXP9|A8MXP9_HUMAN,tr|A0A0R4J2E8|A0A0R4J2E8_HUMAN,tr|D6REM6|D6REM6_HUMAN" 5 1921.936 1.56 32937 17737 2 1921.932279 961.9753 Matrin-3 OS=Homo sapiens OX=9606 GN=MATR3 PE=1 SV=2 3.83 3068.3 - 593450 - - - -1.9444 - 3.275 0.619 - 458.8 1 2 0 -0.0037 17 0 0 0 2.79E+07 1.78E+07 - - - 6.5284 0.9999 221125_WJC_METTL3_EV_vs_WT_F03.17740.17740.2 0.000252 24-Nov R.DMFASVGADGSVR[166.11].M "sp|P61962|DCAF7_HUMAN,tr|A0A087WWI6|A0A087WWI6_HUMAN" 2 1320.6008 1.21 32939 17740 2 1320.600024 661.3077 DDB1- and CUL4-associated factor 7 OS=Homo sapiens OX=9606 GN=DCAF7 PE=1 SV=1 4.21 3068.6 - 5.02E+06 - - - -0.5649 - 2.452 0.572 - 469.4 1 2 0 -0.0007 13 0 0 0 7.06E+07 5.85E+07 - - - 5.5675 0.9998 221125_WJC_METTL3_EV_vs_WT_F03.17742.17742.2 6.32E-05 22-Sep K.SLPSAVYC[160.03]IEDK.M sp|O43290|SNUT1_HUMAN 1 1380.6595 1.84 32941 17742 2 1380.658214 691.337 U4\U6.U5 tri-snRNP-associated protein 1 OS=Homo sapiens OX=9606 GN=SART1 PE=1 SV=1 4.37 3068.7 - 3.53E+06 - - - -0.9445 - 1.879 0.466 - 221.1 1 2 0 -0.0013 12 0 0 0 2.75E+07 1.50E+07 - - - 4.142 0.9998 221125_WJC_METTL3_EV_vs_WT_F03.17743.17743.2 1.11E-05 13/26 K.ELTASVTEAIPVSR.D sp|P48634|PRC2A_HUMAN 1 1471.7882 2.51 32942 17743 2 1471.785966 736.9014 Protein PRRC2A OS=Homo sapiens OX=9606 GN=PRRC2A PE=1 SV=3 4.53 3068.8 - 2.75E+06 - - - -1.5335 - 2.528 0.476 - 575.1 1 2 0 -0.0023 14 0 0 0 2.86E+07 1.14E+07 - - - 4.8834 1 221125_WJC_METTL3_EV_vs_WT_F03.17744.17744.2 6.48E-08 19/32 K.IEELDQENEAALENGIK.N "sp|P43243|MATR3_HUMAN,tr|B3KM87|B3KM87_HUMAN,tr|A8MXP9|A8MXP9_HUMAN,tr|A0A0R4J2E8|A0A0R4J2E8_HUMAN,tr|D6REM6|D6REM6_HUMAN" 5 1913.9218 1.56 32943 17744 2 1913.919562 957.9682 Matrin-3 OS=Homo sapiens OX=9606 GN=MATR3 PE=1 SV=2 3.83 3068.9 - 1.99E+06 - - - -1.1777 - 3.809 0.572 - 1119.5 1 2 0 -0.0023 17 0 0 0 2.79E+07 1.78E+07 - - - 6.5531 0.9883 221125_WJC_METTL3_EV_vs_WT_F03.17746.17746.2 0.00481 18-Dec L.GLDLSNGK[136.11]PR[166.11].D "sp|P17987|TCPA_HUMAN,tr|F5H282|F5H282_HUMAN,tr|E7EQR6|E7EQR6_HUMAN" 3 1073.5948 0.43 32945 17746 2 1073.593822 537.8047 T-complex protein 1 subunit alpha OS=Homo sapiens OX=9606 GN=TCP1 PE=1 SV=1 8.75 3069.2 - 1.89E+06 - - - -0.9361 - 2.312 0.397 - 639.5 1 1 0 -0.001 10 0 0 0 6.94E+06 1.62E+07 - - - 4.3124 1 221125_WJC_METTL3_EV_vs_WT_F03.17747.17747.2 1.76E-07 14-Dec K.HVFFFDTK.K sp|Q9Y3A2|UTP11_HUMAN 1 1039.5127 1.13 32946 17747 2 1039.510944 520.7636 Probable U3 small nucleolar RNA-associated protein 11 OS=Homo sapiens OX=9606 GN=UTP11 PE=1 SV=2 6.74 3069.3 - 1.70E+06 - - - -1.7056 - 2.415 0.556 - 568.5 1 2 0 -0.0018 8 0 0 0 9.54E+06 8.45E+06 - - - 5.8062 0.9997 221125_WJC_METTL3_EV_vs_WT_F03.17748.17748.3 3.59E-06 Nov-52 K.GPVEGYEENEEFLR.T sp|Q9UI30|TR112_HUMAN 1 1666.7475 1.51 32947 17748 3 1666.744265 556.5898 Multifunctional methyltransferase subunit TRM112-like protein OS=Homo sapiens OX=9606 GN=TRMT112 PE=1 SV=1 3.98 3069.4 - 1.65E+06 - - - -1.9295 - 2.175 0.372 - 202.1 1 2 0 -0.0032 14 0 0 0 3.23E+07 2.14E+07 - - - 4.7515 0.9911 221125_WJC_METTL3_EV_vs_WT_F03.17749.17749.2 0.000604 20-Oct E.SLTEELAYLKK.N "sp|P13645|K1C10_HUMAN,tr|A0A1B0GVI3|A0A1B0GVI3_HUMAN" 2 1293.718 999 32948 17749 2 1293.71719 647.8663 "Keratin, type I cytoskeletal 10 OS=Homo sapiens OX=9606 GN=KRT10 PE=1 SV=6" 5.86 3069.5 - 1.63E+06 - - - -0.64 - 2.235 0.458 - 272.4 1 1 0 -0.0008 11 0 0 0 1.03E+07 0.00E+00 - - - 4.5992 0.9998 221125_WJC_METTL3_EV_vs_WT_F03.17750.17750.2 8.61E-08 22-Nov R.ESNYFGLSPEER.R sp|Q01804|OTUD4_HUMAN 1 1426.6365 1.54 32949 17750 2 1426.638373 714.3255 OTU domain-containing protein 4 OS=Homo sapiens OX=9606 GN=OTUD4 PE=1 SV=4 4.25 3069.5 - 1.48E+06 - - - 1.3311 - 2.134 0.458 - 471.3 1 2 0 0.0019 12 0 0 0 1.20E+07 7.79E+06 - - - 4.4176 0.9804 221125_WJC_METTL3_EV_vs_WT_F03.17752.17752.2 0.00122 18-Nov L.GLDLSNGKPR.D "sp|P17987|TCPA_HUMAN,tr|F5H282|F5H282_HUMAN,tr|E7EQR6|E7EQR6_HUMAN" 3 1055.5724 0.43 32951 17752 2 1055.571024 528.7935 T-complex protein 1 subunit alpha OS=Homo sapiens OX=9606 GN=TCP1 PE=1 SV=1 8.75 3069.8 - 1.07E+06 - - - -1.2628 - 2.166 0.355 - 487.9 1 1 0 -0.0013 10 0 0 0 6.94E+06 1.61E+07 - - - 3.82 0.9847 221125_WJC_METTL3_EV_vs_WT_F03.17754.17754.3 2.28E-05 15/36 L.R[166.11]YLDVSILGK[136.11].F sp|Q86U44|MTA70_HUMAN 1 1180.6935 0.02 32953 17754 3 1180.689879 394.5718 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 8.59 3070 - 741833 - - - -3.0491 - 2.393 0.46 - 443 1 1 0 -0.0036 10 0 0 0 1.57E+05 8.85E+06 - - - 6.2158 0.9997 221125_WJC_METTL3_EV_vs_WT_F03.17755.17755.3 0.00244 Aug-36 K.VHAYIISYLK.K "sp|Q9H223|EHD4_HUMAN,sp|Q9NZN4|EHD2_HUMAN" 2 1205.6808 1.11 32954 17755 3 1205.677721 402.9009 EH domain-containing protein 4 OS=Homo sapiens OX=9606 GN=EHD4 PE=1 SV=1 8.48 3070.1 - 512035 - - - -2.5911 - 1.825 0.433 - 89.7 1 2 0 -0.0031 10 0 0 0 2.78E+06 2.51E+06 - - - 5.1235 1 221125_WJC_METTL3_EV_vs_WT_F03.17759.17759.3 9.65E-09 19/64 K.IEELDQENEAALENGIK.N "sp|P43243|MATR3_HUMAN,tr|B3KM87|B3KM87_HUMAN,tr|A8MXP9|A8MXP9_HUMAN,tr|A0A0R4J2E8|A0A0R4J2E8_HUMAN,tr|D6REM6|D6REM6_HUMAN" 5 1913.9218 1.93 32957 17759 3 1913.920379 638.9812 Matrin-3 OS=Homo sapiens OX=9606 GN=MATR3 PE=1 SV=2 3.83 3070.5 - 4.10E+06 - - - -0.7508 - 3.515 0.636 - 593.2 1 2 0 -0.0014 17 0 0 0 2.70E+07 1.40E+07 - - - 8.806 1 221125_WJC_METTL3_EV_vs_WT_F03.17761.17761.3 1.32E-08 19/48 R.R[166.11]PQIDPAVEGFIR[166.11].D "sp|Q8WU79|SMAP2_HUMAN,tr|A0A087WV97|A0A087WV97_HUMAN,tr|X6RCC3|X6RCC3_HUMAN" 3 1516.8265 1.81 32959 17761 3 1516.82603 506.6161 Stromal membrane-associated protein 2 OS=Homo sapiens OX=9606 GN=SMAP2 PE=1 SV=1 6.07 3070.6 - 3.76E+06 - - - -0.3112 - 3.39 0.556 - 708.6 1 2 0 -0.0005 13 0 0 0 9.62E+07 5.30E+07 - - - 8.0487 0.9574 221125_WJC_METTL3_EV_vs_WT_F03.17762.17762.2 0.00913 18-Dec L.R[166.11]YLDVSILGK[136.11].F sp|Q86U44|MTA70_HUMAN 1 1180.6935 0.001 32960 17762 2 1180.69155 591.354 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 8.59 3070.7 - 3.70E+06 - - - -1.6338 - 2.372 0.231 - 519.7 1 1 0 -0.0019 10 0 0 0 0.00E+00 2.76E+07 - - - 3.1575 0.9799 221125_WJC_METTL3_EV_vs_WT_F03.17763.17763.3 0.168 Oct-48 R.K[136.11]RAAMSVTLTSVK[136.11].R "tr|C9JWC3|C9JWC3_HUMAN,tr|C9J9D3|C9J9D3_HUMAN,tr|C9J372|C9J372_HUMAN,tr|C9JZ60|C9JZ60_HUMAN,tr|C9JG84|C9JG84_HUMAN,tr|C9J4Z9|C9J4Z9_HUMAN,tr|C9JN77|C9JN77_HUMAN" 7 1406.825 - 32961 17763 3 1406.822343 469.9489 Sorbin and SH3 domain-containing protein 2 (Fragment) OS=Homo sapiens OX=9606 GN=SORBS2 PE=1 SV=1 11.17 3070.8 - 3.65E+06 - - - -1.9029 - 2.056 0.193 - 153.9 1 2 1 -0.0027 13 0 0 0 - - - - - 2.6452 0.9998 221125_WJC_METTL3_EV_vs_WT_F03.17764.17764.3 2.35E-07 Dec-52 K.GPVEGYEENEEFLR[166.11].T sp|Q9UI30|TR112_HUMAN 1 1676.7558 1.51 32962 17764 3 1676.75306 559.9259 Multifunctional methyltransferase subunit TRM112-like protein OS=Homo sapiens OX=9606 GN=TRMT112 PE=1 SV=1 3.98 3070.8 - 2.45E+06 - - - -1.6049 - 2.357 0.377 - 275.1 1 2 0 -0.0027 14 0 0 0 3.23E+07 2.14E+07 - - - 5.021 0.9991 221125_WJC_METTL3_EV_vs_WT_F03.17766.17766.2 7.57E-06 16-Aug K.DYLLC[160.03]DYNR[166.11].D "sp|P47756|CAPZB_HUMAN,tr|B1AK87|B1AK87_HUMAN,tr|B1AK88|B1AK88_HUMAN,tr|A0A6I8PRV6|A0A6I8PRV6_HUMAN,tr|B1AK85|B1AK85_HUMAN" 5 1240.5422 1.06 32964 17766 2 1240.539914 621.2784 F-actin-capping protein subunit beta OS=Homo sapiens OX=9606 GN=CAPZB PE=1 SV=4 4.21 3071 - 1.89E+06 - - - -1.8371 - 1.692 0.337 - 272.2 1 2 0 -0.0023 9 0 0 0 1.25E+07 1.18E+07 - - - 3.0509 1 221125_WJC_METTL3_EV_vs_WT_F03.17769.17769.2 2.73E-06 16/30 K.VSDTVVEPYNATLSVH.Q "sp|P04350|TBB4A_HUMAN,sp|Q9BVA1|TBB2B_HUMAN,sp|A6NNZ2|TBB8B_HUMAN,sp|P07437|TBB5_HUMAN,sp|Q13885|TBB2A_HUMAN,sp|P68371|TBB4B_HUMAN,sp|Q9BUF5|TBB6_HUMAN,sp|Q3ZCM7|TBB8_HUMAN,tr|M0R2D3|M0R2D3_HUMAN,tr|Q5ST81|Q5ST81_HUMAN,tr|Q5JP53|Q5JP53_HUMAN,tr|M0R042|M0R042_HUMAN,tr|K7ESM5|K7ESM5_HUMAN,tr|M0QYM7|M0QYM7_HUMAN,tr|A0A075B736|A0A075B736_HUMAN,tr|Q5SQY0|Q5SQY0_HUMAN" 16 1729.8523 - 32967 17769 2 1729.849695 865.9334 Tubulin beta-4A chain OS=Homo sapiens OX=9606 GN=TUBB4A PE=1 SV=2 4.35 3071.3 - 1.45E+06 - - - -1.4943 - 3.119 0.561 - 823.9 1 1 0 -0.0026 16 0 0 0 - - - - - 5.9804 0.9992 221125_WJC_METTL3_EV_vs_WT_F03.17771.17771.3 0.0135 Oct-44 K.LLDLVQQSC[160.03]NYK[136.11].Q "sp|P55769|NH2L1_HUMAN,tr|B1AHD1|B1AHD1_HUMAN,tr|A0A3B3IUA2|A0A3B3IUA2_HUMAN" 3 1487.7534 0.54 32969 17771 3 1487.750693 496.9251 NHP2-like protein 1 OS=Homo sapiens OX=9606 GN=SNU13 PE=1 SV=3 5.83 3071.6 - 879494 - - - -1.796 - 1.93 0.307 - 133.2 1 2 0 -0.0027 12 0 0 0 9.30E+06 1.71E+07 - - - 3.7846 0.9996 221125_WJC_METTL3_EV_vs_WT_F03.17775.17775.2 1.30E-05 28-Nov K.TPPGVPAPSDPLLC[160.03]K[136.11].F "sp|Q15434|RBMS2_HUMAN,tr|F8VV01|F8VV01_HUMAN,tr|F5H5C8|F5H5C8_HUMAN,tr|F8W1T6|F8W1T6_HUMAN" 4 1555.816 -1 32973 17775 2 1555.812025 778.9153 "RNA-binding motif, single-stranded-interacting protein 2 OS=Homo sapiens OX=9606 GN=RBMS2 PE=1 SV=1" 5.5 3072.1 - 674202 - - - -2.5324 - 2.034 0.517 - 266.3 1 2 0 -0.0039 15 0 0 0 0.00E+00 0.00E+00 - - - 4.6039 0.9948 221125_WJC_METTL3_EV_vs_WT_F03.17776.17776.3 0.000544 Nov-36 L.RYLDVSILGK[136.11].F sp|Q86U44|MTA70_HUMAN 1 1170.6852 - 32974 17776 3 1170.683666 391.2357 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 8.59 3072.2 - 491314 - - - -1.318 - 2.046 0.489 - 270 1 1 0 -0.0015 10 0 0 0 - - - - - 6.0821 0.9999 221125_WJC_METTL3_EV_vs_WT_F03.17778.17778.3 1.45E-06 15/44 K.WIGLDLSNGK[136.11]PR[166.11].D "sp|P17987|TCPA_HUMAN,tr|F5H282|F5H282_HUMAN,tr|E7EQR6|E7EQR6_HUMAN" 3 1372.7582 0.4 32975 17778 3 1372.755998 458.5933 T-complex protein 1 subunit alpha OS=Homo sapiens OX=9606 GN=TCP1 PE=1 SV=1 8.75 3072.4 - 1.95E+07 - - - -1.607 - 2.92 0.38 - 512.5 1 2 0 -0.0022 12 0 0 0 1.72E+08 4.28E+08 - - - 5.7463 0.9998 221125_WJC_METTL3_EV_vs_WT_F03.17779.17779.3 9.12E-06 13/36 K.VTNLFC[160.03]FEHR.V "sp|O95159|ZFPL1_HUMAN,tr|E9PJX1|E9PJX1_HUMAN,tr|E9PNY1|E9PNY1_HUMAN,tr|E9PQA5|E9PQA5_HUMAN,tr|E9PMQ3|E9PMQ3_HUMAN,tr|E9PJ47|E9PJ47_HUMAN,tr|E9PQ47|E9PQ47_HUMAN" 7 1321.6237 1.58 32976 17779 3 1321.618595 441.5485 Zinc finger protein-like 1 OS=Homo sapiens OX=9606 GN=ZFPL1 PE=1 SV=2 6.71 3072.5 - 838936 - - - -3.8937 - 2.358 0.501 - 209.7 1 2 0 -0.0051 10 0 0 0 6.47E+06 4.09E+06 - - - 6.6294 0.9953 221125_WJC_METTL3_EV_vs_WT_F03.17780.17780.3 5.69E-05 14/56 K.R[166.11]GLLQDDAHPTLVTY.A "sp|Q86U44|MTA70_HUMAN,tr|F5H6D8|F5H6D8_HUMAN,tr|H0YFV6|H0YFV6_HUMAN,tr|B4DTN4|B4DTN4_HUMAN" 4 1707.882 0.02 32977 17780 3 1707.87925 570.3013 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 5.21 3072.6 - 3.71E+06 - - - -1.5832 - 2.223 0.517 - 240.7 1 1 0 -0.0027 15 0 0 0 1.95E+07 9.29E+08 - - - 6.3878 0.9996 221125_WJC_METTL3_EV_vs_WT_F03.17783.17783.2 9.77E-05 20-Oct R.NLTGDVC[160.03]AVMR[166.11].V sp|Q92922|SMRC1_HUMAN 1 1244.5881 0.03 32980 17783 2 1244.589639 623.3013 SWI\SNF complex subunit SMARCC1 OS=Homo sapiens OX=9606 GN=SMARCC1 PE=1 SV=3 5.83 3072.9 - 1.96E+06 - - - 1.239 - 1.915 0.4 - 190 1 2 0 0.0015 11 0 0 0 1.88E+07 5.45E+08 - - - 3.7526 1 221125_WJC_METTL3_EV_vs_WT_F03.17788.17788.2 0.000118 14/30 N.TVLSGGTTMYPGIADR.M "sp|P63261|ACTG_HUMAN,sp|P60709|ACTB_HUMAN,tr|A0A804GS07|A0A804GS07_HUMAN,tr|E7EVS6|E7EVS6_HUMAN,tr|A0A6Q8PFE4|A0A6Q8PFE4_HUMAN,tr|A0A2R8Y793|A0A2R8Y793_HUMAN,tr|I3L4N8|I3L4N8_HUMAN" 7 1637.8083 1.2 32985 17788 2 1637.807942 819.9114 "Actin, cytoplasmic 2 OS=Homo sapiens OX=9606 GN=ACTG1 PE=1 SV=1" 5.5 3073.4 - 1.17E+06 - - - -0.2229 - 3.217 0.555 - 500.1 1 1 0 -0.0004 16 0 0 0 8.99E+06 7.51E+06 - - - 6.0128 1 221125_WJC_METTL3_EV_vs_WT_F03.17789.17789.3 2.71E-08 22/72 R.VSPEEVTIYNHPGIQAELR.L sp|Q8TEM1|PO210_HUMAN 1 2151.096 2.68 32986 17789 3 2151.095222 718.0393 Nuclear pore membrane glycoprotein 210 OS=Homo sapiens OX=9606 GN=NUP210 PE=1 SV=3 4.75 3073.6 - 1.08E+06 - - - -0.377 - 3.704 0.532 - 510.1 1 2 0 -0.0008 19 0 0 0 2.21E+07 8.23E+06 - - - 7.688 1 221125_WJC_METTL3_EV_vs_WT_F03.17790.17790.3 9.35E-10 14/128 R.SDSPVPTAPTSGGPK[136.11]PSTASAVPELATDPELEK[136.11].K "sp|Q86U44|MTA70_HUMAN,tr|B4E349|B4E349_HUMAN,tr|F5H6D8|F5H6D8_HUMAN,tr|B4DTN4|B4DTN4_HUMAN" 4 3248.6271 0.001 32987 17790 3 3248.61802 1083.883 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 4.18 3073.7 - 666805 - - - -2.7944 - 2.895 0.59 - 72.5 1 2 0 -0.0091 33 0 0 0 0.00E+00 5.70E+06 - - - 7.5609 0.9591 221125_WJC_METTL3_EV_vs_WT_F03.17794.17794.3 0.00773 Dec-44 D.GIHLLDPDVVAR[166.11].F sp|Q86U44|MTA70_HUMAN 1 1313.7331 0.28 32991 17794 3 1313.730873 438.9183 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 5.21 3074.2 - 456925 - - - -1.699 - 2.407 0.298 - 303.1 1 1 0 -0.0022 12 0 0 0 1.14E+07 4.08E+07 - - - 4.2965 0.9961 221125_WJC_METTL3_EV_vs_WT_F03.17795.17795.3 0.0931 Aug-36 K.VHAYIISYLK[136.11].K "sp|Q9H223|EHD4_HUMAN,sp|Q9NZN4|EHD2_HUMAN" 2 1213.695 1.16 32992 17795 3 1213.695562 405.5723 EH domain-containing protein 4 OS=Homo sapiens OX=9606 GN=EHD4 PE=1 SV=1 8.48 3074.3 - 331481 - - - 0.426 - 1.76 0.197 - 64.7 1 2 0 0.0005 10 0 0 0 2.78E+06 2.39E+06 - - - 2.3872 0.9951 221125_WJC_METTL3_EV_vs_WT_F03.17800.17800.2 2.74E-05 22-Oct K.DSPSVWAAVPGK.T "sp|P07737|PROF1_HUMAN,tr|I3L3D5|I3L3D5_HUMAN" 2 1212.6139 1.15 32995 17800 2 1212.615095 607.3142 Profilin-1 OS=Homo sapiens OX=9606 GN=PFN1 PE=1 SV=2 5.84 3074.8 - 4.25E+06 - - - 0.9954 - 1.958 0.068 - 243.6 1 2 0 0.0012 12 0 0 0 2.95E+07 2.56E+07 - - - 1.3108 0.9999 221125_WJC_METTL3_EV_vs_WT_F03.17801.17801.2 3.18E-06 20-Oct R.NLTGDVC[160.03]AVMR.V sp|Q92922|SMRC1_HUMAN 1 1234.5798 0.04 32996 17801 2 1234.580293 618.2972 SWI\SNF complex subunit SMARCC1 OS=Homo sapiens OX=9606 GN=SMARCC1 PE=1 SV=3 5.83 3074.9 - 3.62E+06 - - - 0.3775 - 2.132 0.597 - 305.3 1 2 0 0.0005 11 0 0 0 2.04E+07 5.45E+08 - - - 5.4983 0.9998 221125_WJC_METTL3_EV_vs_WT_F03.17803.17803.2 0.001 20-Nov K.TLQLDNNFEVK.S sp|Q9UMS4|PRP19_HUMAN 1 1319.6721 1.33 32998 17803 2 1319.670961 660.8433 Pre-mRNA-processing factor 19 OS=Homo sapiens OX=9606 GN=PRPF19 PE=1 SV=1 4.37 3075 - 2.61E+06 - - - -0.8866 - 2.14 0.477 - 290.4 1 2 0 -0.0012 11 0 0 0 1.60E+08 1.20E+08 - - - 4.6219 0.9999 221125_WJC_METTL3_EV_vs_WT_F03.17804.17804.2 7.44E-05 14/22 K.GPSVFPLAPSSK.S "sp|P01857|IGHG1_HUMAN,tr|A0A0A0MS08|A0A0A0MS08_HUMAN,tr|A0A0A0MS07|A0A0A0MS07_HUMAN" 3 1185.6394 0.64 32999 17804 2 1185.640641 593.827 Immunoglobulin heavy constant gamma 1 OS=Homo sapiens OX=9606 GN=IGHG1 PE=1 SV=1 8.75 3075 - 2.58E+06 - - - 1.0686 - 2.57 0.504 - 733.4 1 2 0 0.0013 12 0 0 0 3.19E+07 4.98E+07 - - - 5.2467 1 221125_WJC_METTL3_EV_vs_WT_F03.17805.17805.3 1.68E-06 14/52 K.REDLVVAPAGITLK.E "sp|P12268|IMDH2_HUMAN,tr|A0A7I2YQK5|A0A7I2YQK5_HUMAN,tr|H0Y4R1|H0Y4R1_HUMAN,tr|A0A7I2V2T3|A0A7I2V2T3_HUMAN,tr|E7ETK5|E7ETK5_HUMAN" 5 1480.8613 0.61 33000 17805 3 1480.861021 494.6277 Inosine-5'-monophosphate dehydrogenase 2 OS=Homo sapiens OX=9606 GN=IMPDH2 PE=1 SV=2 6.07 3075.1 - 2.48E+06 - - - -0.208 - 2.576 0.552 - 346.6 1 2 0 -0.0003 14 0 0 0 1.41E+07 2.31E+07 - - - 7.2088 1 221125_WJC_METTL3_EV_vs_WT_F03.17806.17806.3 3.49E-08 17/64 K.IEELDQENEAALENGIK[136.11].N "sp|P43243|MATR3_HUMAN,tr|B3KM87|B3KM87_HUMAN,tr|A8MXP9|A8MXP9_HUMAN,tr|A0A0R4J2E8|A0A0R4J2E8_HUMAN,tr|D6REM6|D6REM6_HUMAN" 5 1921.936 1.93 33001 17806 3 1921.933904 641.6526 Matrin-3 OS=Homo sapiens OX=9606 GN=MATR3 PE=1 SV=2 3.83 3075.1 - 2.33E+06 - - - -1.0989 - 3.023 0.59 - 515.7 1 2 0 -0.0021 17 0 0 0 2.70E+07 1.40E+07 - - - 7.9121 0.978 221125_WJC_METTL3_EV_vs_WT_F03.17807.17807.2 0.000156 15/28 K.R[166.11]GLLQDDAHPTLVTY.A "sp|Q86U44|MTA70_HUMAN,tr|F5H6D8|F5H6D8_HUMAN,tr|H0YFV6|H0YFV6_HUMAN,tr|B4DTN4|B4DTN4_HUMAN" 4 1707.882 0 33002 17807 2 1707.879889 854.9483 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 5.21 3075.3 - 2.28E+06 - - - -1.2091 - 1.637 0.459 - 526.3 1 1 0 -0.0021 15 0 0 0 2.07E+05 9.21E+07 - - - 3.6423 0.9997 221125_WJC_METTL3_EV_vs_WT_F03.17809.17809.2 6.29E-05 20-Dec K.TLQLDNNFEVK[136.11].S sp|Q9UMS4|PRP19_HUMAN 1 1327.6863 1.32 33004 17809 2 1327.683905 664.8504 Pre-mRNA-processing factor 19 OS=Homo sapiens OX=9606 GN=PRPF19 PE=1 SV=1 4.37 3075.4 - 2.15E+06 - - - -1.8272 - 2.094 0.497 - 358.8 1 2 0 -0.0024 11 0 0 0 1.59E+08 1.20E+08 - - - 4.7105 0.8764 221125_WJC_METTL3_EV_vs_WT_F03.17810.17810.3 0.00252 15/60 K.VSDTVVEPYNATLSVH.Q "sp|P04350|TBB4A_HUMAN,sp|Q9BVA1|TBB2B_HUMAN,sp|A6NNZ2|TBB8B_HUMAN,sp|P07437|TBB5_HUMAN,sp|Q13885|TBB2A_HUMAN,sp|P68371|TBB4B_HUMAN,sp|Q9BUF5|TBB6_HUMAN,sp|Q3ZCM7|TBB8_HUMAN,tr|M0R2D3|M0R2D3_HUMAN,tr|Q5ST81|Q5ST81_HUMAN,tr|Q5JP53|Q5JP53_HUMAN,tr|M0R042|M0R042_HUMAN,tr|K7ESM5|K7ESM5_HUMAN,tr|M0QYM7|M0QYM7_HUMAN,tr|A0A075B736|A0A075B736_HUMAN,tr|Q5SQY0|Q5SQY0_HUMAN" 16 1729.8523 - 33005 17810 3 1729.858493 577.6247 Tubulin beta-4A chain OS=Homo sapiens OX=9606 GN=TUBB4A PE=1 SV=2 4.35 3075.5 - 1.25E+06 - - - 3.5916 - 2.395 0.33 - 223.1 1 1 0 0.0062 16 0 0 0 - - - - - 4.4584 1 221125_WJC_METTL3_EV_vs_WT_F03.17811.17811.3 6.48E-05 14/44 R.FYQVPVPLPDR[166.11]R[166.11].R "sp|Q9Y2R9|RT07_HUMAN,tr|J3QLS3|J3QLS3_HUMAN,tr|J3QQS1|J3QQS1_HUMAN,tr|J3KSI8|J3KSI8_HUMAN" 4 1505.8258 38.06 33006 17811 3 1505.824918 502.9492 "28S ribosomal protein S7, mitochondrial OS=Homo sapiens OX=9606 GN=MRPS7 PE=1 SV=2" 8.75 3075.6 - 1.23E+06 - - - -0.5678 - 2.21 0.481 - 211.9 1 2 0 -0.0009 12 0 0 0 4.45E+08 1.17E+07 - - - 6.1005 0.9998 221125_WJC_METTL3_EV_vs_WT_F03.17812.17812.2 4.23E-05 16-Oct R.ENEVLEAWK[136.11].S "sp|Q01082|SPTB2_HUMAN,tr|A0A087WUZ3|A0A087WUZ3_HUMAN" 2 1124.5593 1.34 33007 17812 2 1124.558347 563.2869 "Spectrin beta chain, non-erythrocytic 1 OS=Homo sapiens OX=9606 GN=SPTBN1 PE=1 SV=2" 4.25 3075.7 - 1.22E+06 - - - -0.8821 - 1.867 0.46 - 253.2 1 2 0 -0.001 9 0 0 0 1.22E+07 9.11E+06 - - - 4.2445 0.9999 221125_WJC_METTL3_EV_vs_WT_F03.17814.17814.3 0.00749 13/36 K.VTNLFC[160.03]FEHR[166.11].V "sp|O95159|ZFPL1_HUMAN,tr|E9PJX1|E9PJX1_HUMAN,tr|E9PNY1|E9PNY1_HUMAN,tr|E9PQA5|E9PQA5_HUMAN,tr|E9PMQ3|E9PMQ3_HUMAN,tr|E9PJ47|E9PJ47_HUMAN,tr|E9PQ47|E9PQ47_HUMAN" 7 1331.632 1.58 33009 17814 3 1331.630192 444.8846 Zinc finger protein-like 1 OS=Homo sapiens OX=9606 GN=ZFPL1 PE=1 SV=2 6.71 3075.9 - 959223 - - - -1.366 - 2.096 0.402 - 215.2 1 2 0 -0.0018 10 0 0 0 6.47E+06 4.09E+06 - - - 5.1826 0.9997 221125_WJC_METTL3_EV_vs_WT_F03.17821.17821.2 0.23 18-Nov R.INEILSNALK.R "sp|P52272|HNRPM_HUMAN,tr|M0R019|M0R019_HUMAN,tr|A0A087X0X3|A0A087X0X3_HUMAN" 3 1113.6394 1.71 33015 17821 2 1113.639215 557.827 Heterogeneous nuclear ribonucleoprotein M OS=Homo sapiens OX=9606 GN=HNRNPM PE=1 SV=3 6 3076.8 - 8.31E+06 - - - -0.1428 - 2.334 0.273 - 384.9 1 2 0 -0.0002 10 0 0 0 5.18E+07 3.04E+07 - - - 3.4232 0.9997 221125_WJC_METTL3_EV_vs_WT_F03.17823.17823.2 0.0417 18-Oct R.INEILSNALK[136.11].R "sp|P52272|HNRPM_HUMAN,tr|M0R019|M0R019_HUMAN,tr|A0A087X0X3|A0A087X0X3_HUMAN" 3 1121.6536 1.71 33017 17823 2 1121.653604 561.8341 Heterogeneous nuclear ribonucleoprotein M OS=Homo sapiens OX=9606 GN=HNRNPM PE=1 SV=3 6 3076.9 - 5.11E+06 - - - 0.0267 - 2.246 0.291 - 294.8 1 2 0 0 10 0 0 0 5.18E+07 3.04E+07 - - - 3.4489 1 221125_WJC_METTL3_EV_vs_WT_F03.17825.17825.3 1.52E-07 17/56 R.TPALVFEHVNNTDFK[136.11].Q "sp|P68400|CSK21_HUMAN,sp|Q8NEV1|CSK23_HUMAN,tr|V9GYA2|V9GYA2_HUMAN,tr|A0A2R8YEW1|A0A2R8YEW1_HUMAN,tr|A0A2R8Y4D6|A0A2R8Y4D6_HUMAN,tr|A0A2R8YD58|A0A2R8YD58_HUMAN,tr|A0A2R8YF43|A0A2R8YF43_HUMAN,tr|A0A2R8Y5A0|A0A2R8Y5A0_HUMAN,tr|A0A2R8YDY7|A0A2R8YDY7_HUMAN,tr|A0A2R8Y4H0|A0A2R8Y4H0_HUMAN,tr|E7EU96|E7EU96_HUMAN" 11 1738.877 1.53 33019 17825 3 1738.875631 580.6329 Casein kinase II subunit alpha OS=Homo sapiens OX=9606 GN=CSNK2A1 PE=1 SV=1 5.29 3077.1 - 1.35E+06 - - - -0.7787 - 2.968 0.518 - 365.2 1 2 0 -0.0014 15 0 0 0 1.69E+07 1.10E+07 - - - 7.1535 1 221125_WJC_METTL3_EV_vs_WT_F03.17826.17826.3 1.25E-06 15/56 R.EVIPTHTVYALNIER.L sp|Q96BN2|TADA1_HUMAN 1 1753.9363 0.82 33020 17826 3 1753.933506 585.6527 Transcriptional adapter 1 OS=Homo sapiens OX=9606 GN=TADA1 PE=1 SV=1 5.4 3077.2 - 1.24E+06 - - - -1.5844 - 2.923 0.463 - 308.8 1 2 0 -0.0028 15 0 0 0 1.60E+07 1.95E+07 - - - 6.5001 0.9999 221125_WJC_METTL3_EV_vs_WT_F03.17827.17827.2 3.41E-08 13/26 R.LSYVGNNFGTGALK[136.11].C "sp|Q9GZS1|RPA49_HUMAN,tr|E7EX70|E7EX70_HUMAN" 2 1447.7551 0.1 33021 17827 2 1447.754717 724.8848 DNA-directed RNA polymerase I subunit RPA49 OS=Homo sapiens OX=9606 GN=POLR1E PE=1 SV=3 8.59 3077.4 - 1.24E+06 - - - -0.25 - 2.352 0.578 - 342.2 1 2 0 -0.0004 14 0 0 0 5.62E+06 5.57E+07 - - - 5.4562 1 221125_WJC_METTL3_EV_vs_WT_F03.17828.17828.2 0.000115 18-Nov K.QSNSYDMFMR[166.11].G "sp|P14868|SYDC_HUMAN,tr|H7BZ35|H7BZ35_HUMAN" 2 1287.5252 0.87 33022 17828 2 1287.522898 644.7699 "Aspartate--tRNA ligase, cytoplasmic OS=Homo sapiens OX=9606 GN=DARS1 PE=1 SV=2" 5.84 3077.5 - 992137 - - - -1.7592 - 2.201 0.613 - 581.6 1 2 0 -0.0023 10 0 0 0 5.99E+06 6.90E+06 - - - 5.77 0.7924 221125_WJC_METTL3_EV_vs_WT_F03.17830.17830.2 0.0285 16-Oct A.QNQVLNLIK.A "sp|P15927|RFA2_HUMAN,tr|Q5TEJ0|Q5TEJ0_HUMAN" 2 1068.6291 1.78 33024 17830 2 1068.629133 535.3218 Replication protein A 32 kDa subunit OS=Homo sapiens OX=9606 GN=RPA2 PE=1 SV=1 8.75 3077.8 - 689088 - - - -0.0103 - 1.602 0.108 - 263 1 1 0 0 9 0 0 0 7.20E+06 4.05E+06 - - - 1.202 0.9999 221125_WJC_METTL3_EV_vs_WT_F03.17832.17832.3 9.43E-05 Nov-36 K.FFEHFIEGGR[166.11].T "sp|Q96FW1|OTUB1_HUMAN,tr|F5H3F0|F5H3F0_HUMAN,tr|F5GYN4|F5GYN4_HUMAN,tr|F5GYJ8|F5GYJ8_HUMAN,tr|J3KR44|J3KR44_HUMAN,tr|F5H6Q1|F5H6Q1_HUMAN" 6 1247.5963 0.62 33026 17832 3 1247.595839 416.8727 Ubiquitin thioesterase OTUB1 OS=Homo sapiens OX=9606 GN=OTUB1 PE=1 SV=2 5.4 3078 - 644764 - - - -0.3511 - 2.131 0.44 - 106.7 1 2 0 -0.0004 10 0 0 0 4.49E+06 7.24E+06 - - - 5.655 1 221125_WJC_METTL3_EV_vs_WT_F03.17833.17833.2 3.01E-10 18/34 R.IYELAAGGTAVGTGLNTR.L "sp|P07954|FUMH_HUMAN,tr|A0A804HI24|A0A804HI24_HUMAN" 2 1762.9214 2.61 33027 17833 2 1762.925562 882.468 "Fumarate hydratase, mitochondrial OS=Homo sapiens OX=9606 GN=FH PE=1 SV=3" 6 3078.1 - 540801 - - - 2.3818 - 3.671 0.569 - 950.8 1 2 0 0.0042 18 0 0 0 4.18E+06 1.60E+06 - - - 6.4396 0.9752 221125_WJC_METTL3_EV_vs_WT_F03.17834.17834.2 0.000185 16-Oct A.QNQVLNLIK[136.11].A "sp|P15927|RFA2_HUMAN,tr|Q5TEJ0|Q5TEJ0_HUMAN" 2 1076.6433 1.67 33028 17834 2 1076.642027 539.3289 Replication protein A 32 kDa subunit OS=Homo sapiens OX=9606 GN=RPA2 PE=1 SV=1 8.75 3078.3 - 510694 - - - -1.2232 - 1.902 0.353 - 278.8 1 1 0 -0.0013 9 0 0 0 6.75E+06 4.05E+06 - - - 3.5078 1 221125_WJC_METTL3_EV_vs_WT_F03.17835.17835.3 1.67E-08 15/40 K.TPFLGDMAHIR[166.11].- "sp|Q9H857|NT5D2_HUMAN,tr|H7C519|H7C519_HUMAN" 2 1266.6418 0.4 33029 17835 3 1266.642919 423.2212 5'-nucleotidase domain-containing protein 2 OS=Homo sapiens OX=9606 GN=NT5DC2 PE=1 SV=1 6.41 3078.4 - 470659 - - - 0.8463 - 2.778 0.547 - 374.5 1 2 0 0.0011 11 0 0 0 1.09E+06 2.70E+06 - - - 7.5408 0.9999 221125_WJC_METTL3_EV_vs_WT_F03.17836.17836.2 1.89E-06 28-Oct R.IAQSDYIPTQQDVLR.T sp|P04899|GNAI2_HUMAN 1 1745.8948 2.4 33030 17836 2 1745.891965 873.9547 Guanine nucleotide-binding protein G(i) subunit alpha-2 OS=Homo sapiens OX=9606 GN=GNAI2 PE=1 SV=3 4.21 3078.5 - 461803 - - - -1.6318 - 2.578 0.567 - 144.6 1 2 0 -0.0028 15 0 0 0 3.29E+06 1.37E+06 - - - 5.5562 0.9994 221125_WJC_METTL3_EV_vs_WT_F03.17837.17837.3 1.14E-05 Sep-36 K.FFEHFIEGGR.T "sp|Q96FW1|OTUB1_HUMAN,tr|F5H3F0|F5H3F0_HUMAN,tr|F5GYN4|F5GYN4_HUMAN,tr|F5GYJ8|F5GYJ8_HUMAN,tr|J3KR44|J3KR44_HUMAN,tr|F5H6Q1|F5H6Q1_HUMAN" 6 1237.588 0.62 33031 17837 3 1237.583027 413.5366 Ubiquitin thioesterase OTUB1 OS=Homo sapiens OX=9606 GN=OTUB1 PE=1 SV=2 5.4 3078.7 - 404796 - - - -4.024 - 1.929 0.448 - 72.5 1 2 0 -0.005 10 0 0 0 4.49E+06 7.24E+06 - - - 5.4521 0.9998 221125_WJC_METTL3_EV_vs_WT_F03.17839.17839.2 0.000111 22-Nov K.DSPSVWAAVPGK[136.11].T "sp|P07737|PROF1_HUMAN,tr|I3L3D5|I3L3D5_HUMAN" 2 1220.6281 2.4 33032 17839 2 1220.626886 611.3213 Profilin-1 OS=Homo sapiens OX=9606 GN=PFN1 PE=1 SV=2 5.84 3078.9 - 2.21E+06 - - - -0.9847 - 1.935 0.518 - 303 1 2 0 -0.0012 12 0 0 0 6.58E+07 2.75E+07 - - - 4.6034 1 221125_WJC_METTL3_EV_vs_WT_F03.17842.17842.3 0.00508 17/44 K.TTITMAHLLAAR.E sp|Q52LJ0|FA98B_HUMAN 1 1297.7176 1.26 33034 17842 3 1297.715818 433.5798 Protein FAM98B OS=Homo sapiens OX=9606 GN=FAM98B PE=1 SV=2 9.44 3079.1 - 3.59E+06 - - - -1.4048 - 3.075 0.488 - 611 1 2 0 -0.0018 12 0 0 0 3.61E+07 2.86E+07 - - - 7.0938 1 221125_WJC_METTL3_EV_vs_WT_F03.17843.17843.2 1.79E-10 17/24 K.VNDTIQIDLETGK[136.11].L sp|P62701|RS4X_HUMAN 1 1452.7551 1.09 33035 17843 2 1452.752681 727.3848 "40S ribosomal protein S4, X isoform OS=Homo sapiens OX=9606 GN=RPS4X PE=1 SV=2" 4.03 3079.2 - 4.75E+06 - - - -1.692 - 3.596 0.595 - 1615.6 1 2 0 -0.0025 13 0 0 0 6.08E+08 5.57E+08 - - - 6.7196 0.9999 221125_WJC_METTL3_EV_vs_WT_F03.17845.17845.3 0.000118 Nov-56 R.EVIPTHTVYALNIER[166.11].L sp|Q96BN2|TADA1_HUMAN 1 1763.9446 1.19 33037 17845 3 1763.942045 588.9888 Transcriptional adapter 1 OS=Homo sapiens OX=9606 GN=TADA1 PE=1 SV=1 5.4 3079.3 - 2.34E+06 - - - -1.4229 - 2.342 0.452 - 185.8 1 2 0 -0.0025 15 0 0 0 1.55E+07 1.30E+07 - - - 5.7992 1 221125_WJC_METTL3_EV_vs_WT_F03.17848.17848.3 2.68E-06 15/40 K.IIFSEHLPLSK.L "sp|Q9Y2L1|RRP44_HUMAN,tr|F2Z2C0|F2Z2C0_HUMAN,tr|G3V1J5|G3V1J5_HUMAN" 3 1282.7285 1.69 33040 17848 3 1282.72991 428.5835 Exosome complex exonuclease RRP44 OS=Homo sapiens OX=9606 GN=DIS3 PE=1 SV=2 6.75 3079.5 - 1.49E+06 - - - 1.0805 - 2.729 0.489 - 390.2 1 2 0 0.0014 11 0 0 0 2.42E+08 1.43E+08 - - - 6.8435 1 221125_WJC_METTL3_EV_vs_WT_F03.17850.17850.2 2.46E-07 22-Dec K.SPYQEFTDHLVK[136.11].T "sp|P15880|RS2_HUMAN,tr|E9PQD7|E9PQD7_HUMAN,tr|H0YEN5|H0YEN5_HUMAN" 3 1470.7234 1.02 33042 17850 2 1470.723529 736.369 40S ribosomal protein S2 OS=Homo sapiens OX=9606 GN=RPS2 PE=1 SV=2 5.3 3079.8 - 1.27E+06 - - - 0.0571 - 2.506 0.62 - 295.4 1 2 0 0.0001 12 0 0 0 5.79E+06 5.66E+06 - - - 6.0375 1 221125_WJC_METTL3_EV_vs_WT_F03.17853.17853.2 8.73E-06 15/28 R.VLTTGYWPTQSATPK.C "sp|Q13618|CUL3_HUMAN,tr|A0A087WTG3|A0A087WTG3_HUMAN" 2 1648.8461 5.32 33045 17853 2 1648.846829 825.4303 Cullin-3 OS=Homo sapiens OX=9606 GN=CUL3 PE=1 SV=2 8.56 3080.1 - 877911 - - - 0.4585 - 2.788 0.587 - 467.8 1 2 0 0.0008 15 0 0 0 1.27E+07 2.39E+06 - - - 5.8972 0.9999 221125_WJC_METTL3_EV_vs_WT_F03.17854.17854.3 0.00329 16/44 K.LALDMEISAYR[166.11]K[136.11].L "sp|P20700|LMNB1_HUMAN,tr|E9PBF6|E9PBF6_HUMAN" 2 1426.7609 1.29 33046 17854 3 1426.75725 476.5942 Lamin-B1 OS=Homo sapiens OX=9606 GN=LMNB1 PE=1 SV=2 6.07 3080.2 - 870654 - - - -2.5624 - 2.632 0.455 - 467.4 1 2 0 -0.0037 12 0 0 0 1.33E+07 1.03E+07 - - - 6.2942 0.9999 221125_WJC_METTL3_EV_vs_WT_F03.17855.17855.3 0.0392 16/56 K.LLSDPNYGVHLPAVK.L sp|Q9BTV4|TMM43_HUMAN 1 1621.8828 0.01 33047 17855 3 1621.882992 541.6349 Transmembrane protein 43 OS=Homo sapiens OX=9606 GN=TMEM43 PE=1 SV=1 6.74 3080.3 - 841721 - - - 0.1233 - 2.645 0.349 - 285.5 1 2 0 0.0002 15 0 0 0 3.64E+06 4.13E+08 - - - 4.969 0.9893 221125_WJC_METTL3_EV_vs_WT_F03.17856.17856.2 1.93E-05 17/24 R.IAEAEIENLTGAR[166.11].H "sp|Q8N6M0|OTU6B_HUMAN,tr|A0A087X0W9|A0A087X0W9_HUMAN" 2 1395.7233 0.88 33048 17856 2 1395.712479 698.8689 Deubiquitinase OTUD6B OS=Homo sapiens OX=9606 GN=OTUD6B PE=1 SV=1 4.25 3080.5 - 589676 - - - -7.773 - 3.145 0.466 - 1254.1 1 2 0 -0.0109 13 0 0 0 7.28E+06 8.28E+06 - - - 5.4202 1 221125_WJC_METTL3_EV_vs_WT_F03.17862.17862.3 0.0182 16/44 K.TTITMAHLLAAR[166.11].E sp|Q52LJ0|FA98B_HUMAN 1 1307.7259 1.26 33053 17862 3 1307.724265 436.9159 Protein FAM98B OS=Homo sapiens OX=9606 GN=FAM98B PE=1 SV=2 9.44 3081.2 - 4.73E+06 - - - -1.2587 - 3.145 0.472 - 513.6 1 2 0 -0.0016 12 0 0 0 3.61E+07 2.86E+07 - - - 6.9779 0.9974 221125_WJC_METTL3_EV_vs_WT_F03.17863.17863.2 0.033 22-Oct K.TGQPMINLYTDR.E "sp|P35637|FUS_HUMAN,tr|H3BPE7|H3BPE7_HUMAN" 2 1407.6816 184.2 33054 17863 2 1407.683309 704.8481 RNA-binding protein FUS OS=Homo sapiens OX=9606 GN=FUS PE=1 SV=1 5.5 3081.3 - 649767 - - - 1.1785 - 1.385 0.266 - 235.6 1 2 0 0.0017 12 0 0 0 1.97E+08 1.07E+06 - - - 1.8621 0.9999 221125_WJC_METTL3_EV_vs_WT_F03.17864.17864.2 0.00012 18-Dec K.DLQNVNITLR.L "sp|P35232|PHB_HUMAN,tr|C9JZ20|C9JZ20_HUMAN,tr|E7ESE2|E7ESE2_HUMAN,tr|E9PCW0|E9PCW0_HUMAN,tr|C9JW96|C9JW96_HUMAN" 5 1184.6513 1.33 33055 17864 2 1184.651295 593.3329 Prohibitin OS=Homo sapiens OX=9606 GN=PHB PE=1 SV=1 5.84 3081.4 - 5.98E+06 - - - -0.0346 - 2.24 0.444 - 592.3 1 2 0 0 10 0 0 0 1.85E+08 1.40E+08 - - - 4.5715 0.9997 221125_WJC_METTL3_EV_vs_WT_F03.17866.17866.2 5.40E-06 14/22 K.LALDVEIATYRK.L "sp|P48668|K2C6C_HUMAN,sp|Q01546|K22O_HUMAN,sp|P12035|K2C3_HUMAN,sp|P04259|K2C6B_HUMAN,sp|P13647|K2C5_HUMAN,sp|P35908|K22E_HUMAN,sp|O95678|K2C75_HUMAN,sp|Q5XKE5|K2C79_HUMAN,sp|P02538|K2C6A_HUMAN,tr|H0YI76|H0YI76_HUMAN,tr|H0YID6|H0YID6_HUMAN" 11 1390.782 999 33057 17866 2 1390.782557 696.3983 "Keratin, type II cytoskeletal 6C OS=Homo sapiens OX=9606 GN=KRT6C PE=1 SV=3" 6.07 3081.5 - 2.59E+06 - - - 0.389 - 2.685 0.265 - 849.3 1 2 0 0.0005 12 0 0 0 4.56E+07 0.00E+00 - - - 3.5969 0.9999 221125_WJC_METTL3_EV_vs_WT_F03.17867.17867.3 0.000973 Dec-40 K.IIFSEHLPLSK[136.11].L "sp|Q9Y2L1|RRP44_HUMAN,tr|F2Z2C0|F2Z2C0_HUMAN,tr|G3V1J5|G3V1J5_HUMAN" 3 1290.7427 1.71 33058 17867 3 1290.740515 431.2549 Exosome complex exonuclease RRP44 OS=Homo sapiens OX=9606 GN=DIS3 PE=1 SV=2 6.75 3081.6 - 1.98E+06 - - - -1.7114 - 2.688 0.392 - 201.8 1 2 0 -0.0022 11 0 0 0 2.41E+08 1.41E+08 - - - 5.7188 1 221125_WJC_METTL3_EV_vs_WT_F03.17868.17868.2 4.21E-07 15/22 K.SPYQEFTDHLVK.T "sp|P15880|RS2_HUMAN,tr|E9PQD7|E9PQD7_HUMAN,tr|H0YEN5|H0YEN5_HUMAN" 3 1462.7092 1.17 33059 17868 2 1462.71026 732.3619 40S ribosomal protein S2 OS=Homo sapiens OX=9606 GN=RPS2 PE=1 SV=2 5.3 3081.7 - 1.18E+06 - - - 0.6939 - 2.789 0.643 - 753.9 1 2 0 0.001 12 0 0 0 3.37E+07 2.88E+07 - - - 6.4886 0.9997 221125_WJC_METTL3_EV_vs_WT_F03.17869.17869.3 4.28E-06 15/52 K.LR[166.11]EIFGLYGQTTGK[136.11].G "sp|Q9NR31|SAR1A_HUMAN,tr|H0Y5E8|H0Y5E8_HUMAN" 2 1599.874 0.99 33060 17869 3 1599.875671 534.2986 GTP-binding protein SAR1a OS=Homo sapiens OX=9606 GN=SAR1A PE=1 SV=1 8.59 3081.8 - 1.09E+06 - - - 1.0682 - 2.6 0.433 - 255.5 1 2 1 0.0017 14 0 0 0 4.67E+07 4.70E+07 - - - 5.9064 0.9995 221125_WJC_METTL3_EV_vs_WT_F03.17871.17871.2 2.09E-05 24-Dec R.VLSINGVDVTEAR[166.11].H "sp|Q14160|SCRIB_HUMAN,tr|A0A669KB89|A0A669KB89_HUMAN,tr|A0A0G2JPP5|A0A0G2JPP5_HUMAN,tr|A0A0G2JNZ2|A0A0G2JNZ2_HUMAN,tr|A0A0G2JMS7|A0A0G2JMS7_HUMAN" 5 1381.7441 7.53 33062 17871 2 1381.747461 691.8793 Protein scribble homolog OS=Homo sapiens OX=9606 GN=SCRIB PE=1 SV=4 4.37 3082.1 - 838629 - - - 2.4585 - 2.294 0.452 - 369 1 2 0 0.0034 13 0 0 0 8.52E+07 1.13E+07 - - - 4.5094 0.999 221125_WJC_METTL3_EV_vs_WT_F03.17872.17872.3 9.47E-06 13/48 K.VNDTIQIDLETGK[136.11].L sp|P62701|RS4X_HUMAN 1 1452.7551 1.36 33063 17872 3 1452.748965 485.259 "40S ribosomal protein S4, X isoform OS=Homo sapiens OX=9606 GN=RPS4X PE=1 SV=2" 4.03 3082.2 - 784293 - - - -4.2499 - 2.887 0.336 - 342 1 2 0 -0.0062 13 0 0 0 3.82E+07 2.81E+07 - - - 5.1589 1 221125_WJC_METTL3_EV_vs_WT_F03.17873.17873.3 1.07E-05 14/40 K.ARPELEELLAK.L "sp|Q96GC5|RM48_HUMAN,tr|F5H702|F5H702_HUMAN,tr|F5H8D0|F5H8D0_HUMAN" 3 1267.7136 0.76 33064 17873 3 1267.712926 423.5785 "39S ribosomal protein L48, mitochondrial OS=Homo sapiens OX=9606 GN=MRPL48 PE=1 SV=2" 4.79 3082.4 - 773901 - - - -0.5332 - 2.549 0.433 - 352.5 1 2 0 -0.0007 11 0 0 0 2.52E+07 3.34E+07 - - - 6.0255 1 221125_WJC_METTL3_EV_vs_WT_F03.17875.17875.2 1.26E-08 14/26 R.ILEDSGFDEQQEFR[166.11].S "sp|O60343|TBCD4_HUMAN,tr|A0A3B3IRT3|A0A3B3IRT3_HUMAN" 2 1721.7772 0.38 33066 17875 2 1721.776528 861.8959 TBC1 domain family member 4 OS=Homo sapiens OX=9606 GN=TBC1D4 PE=1 SV=2 3.83 3082.6 - 689024 - - - -0.3984 - 2.798 0.685 - 629 1 2 0 -0.0007 14 0 0 0 1.28E+06 3.38E+06 - - - 6.6822 0.9982 221125_WJC_METTL3_EV_vs_WT_F03.17877.17877.2 1.33E-05 13/22 K.TTITMAHLLAAR.E sp|Q52LJ0|FA98B_HUMAN 1 1297.7176 1.48 33068 17877 2 1297.711854 649.8661 Protein FAM98B OS=Homo sapiens OX=9606 GN=FAM98B PE=1 SV=2 9.44 3082.9 - 575381 - - - -4.4594 - 2.055 0.502 - 385.8 1 2 0 -0.0058 12 0 0 0 4.94E+06 3.35E+06 - - - 4.6421 0.9998 221125_WJC_METTL3_EV_vs_WT_F03.17879.17879.3 0.0172 15/44 K.LALDVEIATYRK.L "sp|P48668|K2C6C_HUMAN,sp|Q01546|K22O_HUMAN,sp|P12035|K2C3_HUMAN,sp|P04259|K2C6B_HUMAN,sp|P13647|K2C5_HUMAN,sp|P35908|K22E_HUMAN,sp|O95678|K2C75_HUMAN,sp|Q5XKE5|K2C79_HUMAN,sp|P02538|K2C6A_HUMAN,tr|H0YI76|H0YI76_HUMAN,tr|H0YID6|H0YID6_HUMAN" 11 1390.782 257.78 33069 17879 3 1390.781363 464.6013 "Keratin, type II cytoskeletal 6C OS=Homo sapiens OX=9606 GN=KRT6C PE=1 SV=3" 6.07 3083.1 - 5.91E+07 - - - -0.4695 - 2.222 0.345 - 314.9 1 2 0 -0.0007 12 0 0 0 4.89E+08 1.90E+06 - - - 4.5993 1 221125_WJC_METTL3_EV_vs_WT_F03.17880.17880.2 7.64E-10 14/24 K.VNDTIQIDLETGK.L sp|P62701|RS4X_HUMAN 1 1444.7409 1.09 33070 17880 2 1444.740632 723.3777 "40S ribosomal protein S4, X isoform OS=Homo sapiens OX=9606 GN=RPS4X PE=1 SV=2" 4.03 3083.1 - 3.30E+07 - - - -0.2125 - 3.193 0.673 - 1149.2 1 2 0 -0.0003 13 0 0 0 6.08E+08 5.57E+08 - - - 6.9913 1 221125_WJC_METTL3_EV_vs_WT_F03.17881.17881.2 6.83E-07 15/24 K.TGTAEMSSILEER.L "sp|P25705|ATPA_HUMAN,tr|K7ERX7|K7ERX7_HUMAN,tr|K7ESA0|K7ESA0_HUMAN" 3 1422.6661 1.37 33071 17881 2 1422.665065 712.3403 "ATP synthase subunit alpha, mitochondrial OS=Homo sapiens OX=9606 GN=ATP5F1A PE=1 SV=1" 4.25 3083.2 - 5.55E+06 - - - -0.6987 - 3.335 0.655 - 1022.1 1 2 0 -0.001 13 0 0 0 2.81E+08 2.05E+08 - - - 6.9698 1 221125_WJC_METTL3_EV_vs_WT_F03.17883.17883.2 5.53E-10 15/26 R.TVLDPVTGDLSDTR[166.11].T sp|Q15393|SF3B3_HUMAN 1 1497.755 1.8 33073 17883 2 1497.754982 749.8848 Splicing factor 3B subunit 3 OS=Homo sapiens OX=9606 GN=SF3B3 PE=1 SV=4 3.93 3083.3 - 3.08E+06 - - - -0.0267 - 2.984 0.63 - 651.7 1 2 0 0 14 0 0 0 1.40E+08 7.77E+07 - - - 6.4377 0.9944 221125_WJC_METTL3_EV_vs_WT_F03.17884.17884.3 0.000114 Nov-56 K.RGLLQDDAHPTLVTY.A "sp|Q86U44|MTA70_HUMAN,tr|F5H6D8|F5H6D8_HUMAN,tr|H0YFV6|H0YFV6_HUMAN,tr|B4DTN4|B4DTN4_HUMAN" 4 1697.8737 0.02 33074 17884 3 1697.873051 566.9652 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 5.21 3083.4 - 2.39E+06 - - - -0.3728 - 2.346 0.455 - 134.7 1 1 0 -0.0006 15 0 0 0 1.95E+07 9.28E+08 - - - 5.8377 0.9997 221125_WJC_METTL3_EV_vs_WT_F03.17885.17885.2 0.000116 20-Nov K.VISVDELEYRQ.- "sp|Q9NRA8|4ET_HUMAN,tr|B1AKL4|B1AKL4_HUMAN" 2 1349.6827 1.25 33075 17885 2 1349.681589 675.8486 Eukaryotic translation initiation factor 4E transporter OS=Homo sapiens OX=9606 GN=EIF4ENIF1 PE=1 SV=2 4.14 3083.4 - 2.26E+06 - - - -0.8202 - 1.872 0.394 - 443.3 1 2 0 -0.0011 11 0 0 0 8.88E+07 7.12E+07 - - - 3.6469 0.9998 221125_WJC_METTL3_EV_vs_WT_F03.17887.17887.2 6.09E-07 14/20 R.TTYLVLDEADR.M "sp|P17844|DDX5_HUMAN,tr|A0A7I2V5F5|A0A7I2V5F5_HUMAN,tr|J3KRZ1|J3KRZ1_HUMAN,tr|J3QSF1|J3QSF1_HUMAN,tr|A0A7I2V507|A0A7I2V507_HUMAN,tr|J3KTA4|J3KTA4_HUMAN,tr|A0A0G2JLI4|A0A0G2JLI4_HUMAN,tr|A0A7I2V2S0|A0A7I2V2S0_HUMAN" 8 1294.6405 1.61 33077 17887 2 1294.637615 648.3275 Probable ATP-dependent RNA helicase DDX5 OS=Homo sapiens OX=9606 GN=DDX5 PE=1 SV=1 4.03 3083.6 - 1.63E+06 - - - -2.2253 - 2.491 0.569 - 811.5 1 2 0 -0.0029 11 0 0 0 3.49E+08 2.17E+08 - - - 5.7118 0.9998 221125_WJC_METTL3_EV_vs_WT_F03.17889.17889.2 0.00016 16-Sep R.DDNMFQIGK[136.11].M sp|P53999|TCP4_HUMAN 1 1074.4895 0.37 33079 17889 2 1074.488348 538.252 Activated RNA polymerase II transcriptional coactivator p15 OS=Homo sapiens OX=9606 GN=SUB1 PE=1 SV=3 4.21 3083.8 - 1.55E+06 - - - -1.114 - 1.793 0.547 - 258.6 1 2 0 -0.0012 9 0 0 0 5.22E+07 1.42E+08 - - - 4.77 0.9996 221125_WJC_METTL3_EV_vs_WT_F03.17893.17893.2 0.0669 22-Nov R.WTDENIDTVALK[136.11].H "sp|Q14204|DYHC1_HUMAN,tr|A0A7P0T8N2|A0A7P0T8N2_HUMAN,tr|A0A7P0T9C4|A0A7P0T9C4_HUMAN,tr|A0A7P0TBJ7|A0A7P0TBJ7_HUMAN,tr|A0A804HHY6|A0A804HHY6_HUMAN,tr|A0A7P0T9K2|A0A7P0T9K2_HUMAN,tr|A0A7P0TB64|A0A7P0TB64_HUMAN,tr|A0A2R8Y706|A0A2R8Y706_HUMAN,tr|A0A7P0T916|A0A7P0T916_HUMAN,tr|A0A7P0TB75|A0A7P0TB75_HUMAN,tr|A0A7P0T8W5|A0A7P0T8W5_HUMAN,tr|A0A7P0TAF3|A0A7P0TAF3_HUMAN,tr|A0A7P0T9F1|A0A7P0T9F1_HUMAN,tr|A0A7P0TAW9|A0A7P0TAW9_HUMAN,tr|A0A7P0TA13|A0A7P0TA13_HUMAN,tr|A0A7P0TAV5|A0A7P0TAV5_HUMAN,tr|A0A7P0T7V5|A0A7P0T7V5_HUMAN,tr|A0A7P0T9R4|A0A7P0T9R4_HUMAN,tr|A0A2R8Y5T0|A0A2R8Y5T0_HUMAN,tr|A0A7P0T990|A0A7P0T990_HUMAN,tr|A0A2R8YFZ7|A0A2R8YFZ7_HUMAN,tr|A0A7P0T825|A0A7P0T825_HUMAN,tr|A0A2R8Y6H2|A0A2R8Y6H2_HUMAN,tr|A0A7P0TAM4|A0A7P0TAM4_HUMAN" 24 1411.7075 0.77 33083 17893 2 1411.70715 706.861 Cytoplasmic dynein 1 heavy chain 1 OS=Homo sapiens OX=9606 GN=DYNC1H1 PE=1 SV=5 4.03 3084.3 - 775272 - - - -0.2196 - 2.207 0.287 - 316.7 1 2 0 -0.0003 12 0 0 0 1.24E+07 1.61E+07 - - - 3.2436 0.9999 221125_WJC_METTL3_EV_vs_WT_F03.17898.17898.3 2.58E-08 14/52 K.LREIFGLYGQTTGK.G "sp|Q9NR31|SAR1A_HUMAN,tr|H0Y5E8|H0Y5E8_HUMAN" 2 1581.8515 0.99 33086 17898 3 1581.850471 528.2911 GTP-binding protein SAR1a OS=Homo sapiens OX=9606 GN=SAR1A PE=1 SV=1 8.59 3084.9 - 3.11E+06 - - - -0.6454 - 2.799 0.465 - 243.5 1 2 1 -0.001 14 0 0 0 4.66E+07 4.70E+07 - - - 6.4593 0.9801 221125_WJC_METTL3_EV_vs_WT_F03.17899.17899.3 0.00133 13/48 R.FIADQLDHLNVTK.K sp|Q9BQC6|RT63_HUMAN 1 1512.7936 2.1 33087 17899 3 1512.791187 505.2718 "Ribosomal protein 63, mitochondrial OS=Homo sapiens OX=9606 GN=MRPL57 PE=1 SV=1" 5.21 3084.9 - 2.56E+06 - - - -1.6235 - 1.906 0.117 - 133.7 1 2 0 -0.0025 13 0 0 0 1.36E+08 6.45E+07 - - - 1.5926 0.9998 221125_WJC_METTL3_EV_vs_WT_F03.17900.17900.2 2.35E-05 20-Nov R.TTYLVLDEADR[166.11].M "sp|P17844|DDX5_HUMAN,tr|A0A7I2V5F5|A0A7I2V5F5_HUMAN,tr|J3KRZ1|J3KRZ1_HUMAN,tr|J3QSF1|J3QSF1_HUMAN,tr|A0A7I2V507|A0A7I2V507_HUMAN,tr|J3KTA4|J3KTA4_HUMAN,tr|A0A0G2JLI4|A0A0G2JLI4_HUMAN,tr|A0A7I2V2S0|A0A7I2V2S0_HUMAN" 8 1304.6488 1.61 33088 17900 2 1304.646712 653.3317 Probable ATP-dependent RNA helicase DDX5 OS=Homo sapiens OX=9606 GN=DDX5 PE=1 SV=1 4.03 3085 - 4.53E+06 - - - -1.5744 - 2.117 0.559 - 408.2 1 2 0 -0.0021 11 0 0 0 3.49E+08 2.17E+08 - - - 5.1981 0.9999 221125_WJC_METTL3_EV_vs_WT_F03.17903.17903.3 0.000318 Oct-36 K.YLDPSFFQHR.L "sp|Q9HD45|TM9S3_HUMAN,tr|Q5TB53|Q5TB53_HUMAN" 2 1308.6251 1.49 33091 17903 3 1308.62372 437.2157 Transmembrane 9 superfamily member 3 OS=Homo sapiens OX=9606 GN=TM9SF3 PE=1 SV=2 6.74 3085.1 - 2.86E+06 - - - -1.0706 - 1.71 0.454 - 116.5 1 2 0 -0.0014 10 0 0 0 5.24E+07 3.51E+07 - - - 5.1681 0.9999 221125_WJC_METTL3_EV_vs_WT_F03.17904.17904.2 5.27E-06 20-Nov K.VISVDELEYR[166.11]Q.- "sp|Q9NRA8|4ET_HUMAN,tr|B1AKL4|B1AKL4_HUMAN" 2 1359.691 1.28 33092 17904 2 1359.691365 680.8528 Eukaryotic translation initiation factor 4E transporter OS=Homo sapiens OX=9606 GN=EIF4ENIF1 PE=1 SV=2 4.14 3085.2 - 2.69E+06 - - - 0.2934 - 2.22 0.514 - 389.3 1 2 0 0.0004 11 0 0 0 8.88E+07 6.94E+07 - - - 4.9947 1 221125_WJC_METTL3_EV_vs_WT_F03.17905.17905.3 3.15E-05 Dec-48 K.VIQYLAYVASSHK.S "sp|P35579|MYH9_HUMAN,tr|Q5BKV1|Q5BKV1_HUMAN" 2 1477.7929 0.04 33093 17905 3 1477.792214 493.6049 Myosin-9 OS=Homo sapiens OX=9606 GN=MYH9 PE=1 SV=4 8.48 3085.3 - 2.62E+06 - - - -0.4744 - 2.546 0.474 - 159.6 1 2 0 -0.0007 13 0 0 0 1.90E+08 4.84E+09 - - - 6.3582 1 221125_WJC_METTL3_EV_vs_WT_F03.17906.17906.3 8.33E-05 Dec-36 K.YLDPSFFQHR[166.11].L "sp|Q9HD45|TM9S3_HUMAN,tr|Q5TB53|Q5TB53_HUMAN" 2 1318.6334 1.49 33094 17906 3 1318.632558 440.5517 Transmembrane 9 superfamily member 3 OS=Homo sapiens OX=9606 GN=TM9SF3 PE=1 SV=2 6.74 3085.3 - 1.97E+06 - - - -0.6317 - 2.244 0.452 - 186.4 1 2 0 -0.0008 10 0 0 0 5.25E+07 3.52E+07 - - - 5.9396 0.9998 221125_WJC_METTL3_EV_vs_WT_F03.17907.17907.2 0.000563 18-Oct R.FNVPVSLESK[136.11].K "sp|P82979|SARNP_HUMAN,tr|F8VZQ9|F8VZQ9_HUMAN,tr|H0YHG0|H0YHG0_HUMAN" 3 1126.6114 0.5 33095 17907 2 1126.610295 564.313 SAP domain-containing ribonucleoprotein OS=Homo sapiens OX=9606 GN=SARNP PE=1 SV=3 6 3085.4 - 1.68E+06 - - - -0.9586 - 1.813 0.467 - 329.8 1 2 0 -0.0011 10 0 0 0 5.81E+07 1.17E+08 - - - 4.1507 1 221125_WJC_METTL3_EV_vs_WT_F03.17908.17908.2 1.86E-09 21/28 K.VEDVSAVEIVGGATR[166.11].L "sp|Q92598|HS105_HUMAN,tr|A0A0A0MSM0|A0A0A0MSM0_HUMAN" 2 1510.7867 0.12 33096 17908 2 1510.779391 756.4006 Heat shock protein 105 kDa OS=Homo sapiens OX=9606 GN=HSPH1 PE=1 SV=1 4.14 3085.5 - 1.64E+06 - - - -4.8094 - 3.52 0.633 - 1887.3 1 2 0 -0.0073 15 0 0 0 3.63E+07 3.09E+08 - - - 6.808 0.9997 221125_WJC_METTL3_EV_vs_WT_F03.17910.17910.3 0.00141 Nov-36 R.APFDLFENKK.K "sp|P08238|HS90B_HUMAN,sp|Q58FF7|H90B3_HUMAN" 2 1207.6237 0.78 33098 17910 3 1207.622863 403.5485 Heat shock protein HSP 90-beta OS=Homo sapiens OX=9606 GN=HSP90AB1 PE=1 SV=4 6.11 3085.8 - 469166 - - - -0.713 - 1.87 0.351 - 110 1 2 0 -0.0009 10 0 0 0 5.96E+06 7.61E+06 - - - 4.2811 0.9996 221125_WJC_METTL3_EV_vs_WT_F03.17914.17914.2 0.00106 13/22 R.DIIGLAETGSGK.T sp|Q9H0S4|DDX47_HUMAN 1 1159.6085 0.67 33100 17914 2 1159.605682 580.8115 Probable ATP-dependent RNA helicase DDX47 OS=Homo sapiens OX=9606 GN=DDX47 PE=1 SV=1 4.37 3086.3 - 1.18E+06 - - - -2.4025 - 2.365 0.461 - 475.7 1 2 0 -0.0028 12 0 0 0 2.89E+07 4.30E+07 - - - 4.7099 0.9997 221125_WJC_METTL3_EV_vs_WT_F03.17915.17915.2 8.75E-05 22-Dec R.DIIGLAETGSGK[136.11].T sp|Q9H0S4|DDX47_HUMAN 1 1167.6227 0.74 33101 17915 2 1167.62016 584.8186 Probable ATP-dependent RNA helicase DDX47 OS=Homo sapiens OX=9606 GN=DDX47 PE=1 SV=1 4.37 3086.4 - 1.60E+06 - - - -2.148 - 2.444 0.442 - 379.1 1 2 0 -0.0025 12 0 0 0 3.18E+07 4.30E+07 - - - 4.6561 0.9985 221125_WJC_METTL3_EV_vs_WT_F03.17916.17916.2 4.3 13/22 R.ALEQLLENNTTR.S "sp|Q9HBF4|ZFYV1_HUMAN,tr|G3V5N8|G3V5N8_HUMAN" 2 1400.726 2.94 33102 17916 2 1400.72364 701.3703 Zinc finger FYVE domain-containing protein 1 OS=Homo sapiens OX=9606 GN=ZFYVE1 PE=1 SV=1 4.53 3086.6 - 1.55E+06 - - - -1.6541 - 2.504 0.143 - 637.6 1 2 0 -0.0023 12 0 0 0 2.44E+07 8.29E+06 - - - 2.5116 0.9648 221125_WJC_METTL3_EV_vs_WT_F03.17918.17918.2 3.25 28-Jun R.SGLWAGGPAPGQFYR.L sp|P28070|PSB4_HUMAN 1 1562.763 1 33104 17918 2 1562.762137 782.3888 Proteasome subunit beta type-4 OS=Homo sapiens OX=9606 GN=PSMB4 PE=1 SV=4 8.46 3086.8 - 844367 - - - -0.5599 - 1.261 0.11 - 42.1 23 2 0 -0.0009 15 0 0 0 1.53E+07 1.54E+07 - - - -0.185 1 221125_WJC_METTL3_EV_vs_WT_F03.17919.17919.2 2.10E-11 16/28 K.MVMIQDGPLPTGADK.P sp|Q96I24|FUBP3_HUMAN 1 1571.7687 2.1 33105 17919 2 1571.775594 786.8917 Far upstream element-binding protein 3 OS=Homo sapiens OX=9606 GN=FUBP3 PE=1 SV=2 4.21 3086.9 - 838322 - - - 4.3543 - 2.791 0.694 - 680.4 1 1 0 0.0068 15 0 0 0 1.91E+07 9.05E+06 - - - 6.6882 0.9997 221125_WJC_METTL3_EV_vs_WT_F03.17921.17921.3 1.28E-05 13/60 K.LYDLYIEEC[160.03]EK[136.11]EPEVK[136.11].K "sp|Q8NEM7|SP20H_HUMAN,tr|B4E2D5|B4E2D5_HUMAN,tr|R4GND2|R4GND2_HUMAN,tr|F6S7C4|F6S7C4_HUMAN,tr|C9JQS2|C9JQS2_HUMAN" 5 2071.9995 1.02 33107 17921 3 2071.998772 691.6738 Transcription factor SPT20 homolog OS=Homo sapiens OX=9606 GN=SUPT20H PE=1 SV=2 4.14 3087.2 - 767217 - - - -0.3393 - 2.404 0.43 - 148.1 1 2 1 -0.0007 16 0 0 0 9.42E+06 9.23E+06 - - - 5.5845 0.9313 221125_WJC_METTL3_EV_vs_WT_F03.17922.17922.3 0.826 Sep-36 K.KIEALLNLPR.N "sp|Q9NPL8|TIDC1_HUMAN,tr|C9JU35|C9JU35_HUMAN" 2 1165.7183 1.3 33108 17922 3 1165.715252 389.58 "Complex I assembly factor TIMMDC1, mitochondrial OS=Homo sapiens OX=9606 GN=TIMMDC1 PE=1 SV=2" 8.75 3087.3 - 416079 - - - -2.6087 - 1.55 0.128 - 90.3 1 2 0 -0.003 10 0 0 0 6.71E+06 5.14E+06 - - - 1.2461 0.9998 221125_WJC_METTL3_EV_vs_WT_F03.17925.17925.3 2.35E-05 15/44 R.YLYTLVITDK[136.11]EK[136.11].A "sp|P63173|RL38_HUMAN,tr|J3KT73|J3KT73_HUMAN,tr|J3QL01|J3QL01_HUMAN" 3 1500.841 1.09 33109 17925 3 1500.839173 501.2876 60S ribosomal protein L38 OS=Homo sapiens OX=9606 GN=RPL38 PE=1 SV=2 6.07 3087.7 - 7.03E+06 - - - -1.2486 - 2.356 0.49 - 193.3 1 2 1 -0.0019 12 0 0 0 6.55E+09 5.99E+09 - - - 6.3779 0.9999 221125_WJC_METTL3_EV_vs_WT_F03.17926.17926.2 9.42E-07 16/28 K.TPPGVPAPSDPLLC[160.03]K.F "sp|Q15434|RBMS2_HUMAN,tr|F8VV01|F8VV01_HUMAN,tr|F5H5C8|F5H5C8_HUMAN,tr|F8W1T6|F8W1T6_HUMAN" 4 1547.8018 5.64 33110 17926 2 1547.799677 774.9082 "RNA-binding motif, single-stranded-interacting protein 2 OS=Homo sapiens OX=9606 GN=RBMS2 PE=1 SV=1" 5.5 3087.9 - 1.78E+06 - - - -1.349 - 2.69 0.534 - 757.5 1 2 0 -0.0021 15 0 0 0 2.99E+07 5.31E+06 - - - 5.4173 0.9686 221125_WJC_METTL3_EV_vs_WT_F03.17927.17927.2 0.00892 16-Sep R.DTINLLDQR.E sp|Q8NBJ4|GOLM1_HUMAN 1 1086.5669 1.29 33111 17927 2 1086.560297 544.2907 Golgi membrane protein 1 OS=Homo sapiens OX=9606 GN=GOLM1 PE=1 SV=1 4.21 3087.9 - 3.62E+06 - - - -6.111 - 1.926 0.226 - 278.5 1 2 0 -0.0066 9 0 0 0 4.27E+07 3.32E+07 - - - 2.6044 0.9986 221125_WJC_METTL3_EV_vs_WT_F03.17934.17934.2 0.00154 16-Nov R.DTINLLDQR[166.11].E sp|Q8NBJ4|GOLM1_HUMAN 1 1096.5752 1.27 33116 17934 2 1096.571695 549.2949 Golgi membrane protein 1 OS=Homo sapiens OX=9606 GN=GOLM1 PE=1 SV=1 4.21 3088.7 - 2.35E+06 - - - -3.2027 - 2.188 0.328 - 379.4 1 2 0 -0.0035 9 0 0 0 4.27E+07 3.37E+07 - - - 3.7277 0.9999 221125_WJC_METTL3_EV_vs_WT_F03.17935.17935.2 4.88E-06 24-Dec K.VIQYLAYVASSHK.S "sp|P35579|MYH9_HUMAN,tr|Q5BKV1|Q5BKV1_HUMAN" 2 1477.7929 0.06 33117 17935 2 1477.792748 739.9037 Myosin-9 OS=Homo sapiens OX=9606 GN=MYH9 PE=1 SV=4 8.48 3088.8 - 1.26E+06 - - - -0.113 - 2.516 0.51 - 467 1 2 0 -0.0002 13 0 0 0 3.56E+07 6.15E+08 - - - 5.1759 0.7855 221125_WJC_METTL3_EV_vs_WT_F03.17936.17936.2 0.588 18-Oct H.SAVADAVEPR[166.11].S sp|E7EW31|PROB1_HUMAN 1 1023.5224 0.001 33118 17936 2 1023.524528 512.7685 Proline-rich basic protein 1 OS=Homo sapiens OX=9606 GN=PROB1 PE=2 SV=2 4.37 3089 - 890898 - - - 2.0361 - 1.629 0.193 - 151.3 1 1 0 0.0021 10 0 0 0 0.00E+00 1.66E+07 - - - 1.8279 0.9982 221125_WJC_METTL3_EV_vs_WT_F03.17937.17937.2 0.13 18-Jul R.LQIFSVEGQK.A "sp|A6NHR9|SMHD1_HUMAN,tr|J3KTL8|J3KTL8_HUMAN" 2 1147.6237 0.82 33119 17937 2 1147.62256 574.8191 Structural maintenance of chromosomes flexible hinge domain-containing protein 1 OS=Homo sapiens OX=9606 GN=SMCHD1 PE=1 SV=2 6 3089.1 - 725404 - - - -1.0143 - 1.452 0.281 - 102.8 2 2 0 -0.0012 10 0 0 0 2.75E+07 3.37E+07 - - - 2.0226 0.9994 221125_WJC_METTL3_EV_vs_WT_F03.17941.17941.2 1.00E-06 16-Sep R.YNFFTGC[160.03]PK[136.11].A sp|Q99832|TCPH_HUMAN 1 1140.5154 0.24 33121 17941 2 1140.512476 571.265 T-complex protein 1 subunit eta OS=Homo sapiens OX=9606 GN=CCT7 PE=1 SV=2 8.2 3089.5 - 6.16E+06 - - - -2.5339 - 1.98 0.438 - 247.6 1 2 0 -0.0029 9 0 0 0 6.47E+07 2.71E+08 - - - 4.2514 0.9998 221125_WJC_METTL3_EV_vs_WT_F03.17942.17942.3 0.00226 Nov-48 R.FIADQLDHLNVTK[136.11].K sp|Q9BQC6|RT63_HUMAN 1 1520.8078 2.1 33122 17942 3 1520.804437 507.9432 "Ribosomal protein 63, mitochondrial OS=Homo sapiens OX=9606 GN=MRPL57 PE=1 SV=1" 5.21 3089.6 - 4.58E+06 - - - -2.2396 - 2.09 0.443 - 91.9 1 2 0 -0.0034 13 0 0 0 1.36E+08 6.45E+07 - - - 5.4767 0.9984 221125_WJC_METTL3_EV_vs_WT_F03.17943.17943.2 1.62E-05 14/22 R.YLYTLVITDK[136.11]EK[136.11].A "sp|P63173|RL38_HUMAN,tr|J3KT73|J3KT73_HUMAN,tr|J3QL01|J3QL01_HUMAN" 3 1500.841 1.09 33123 17943 2 1500.839523 751.4278 60S ribosomal protein L38 OS=Homo sapiens OX=9606 GN=RPL38 PE=1 SV=2 6.07 3089.6 - 3.04E+06 - - - -1.0154 - 2.308 0.497 - 649.6 1 2 1 -0.0015 12 0 0 0 8.57E+08 7.83E+08 - - - 4.912 0.9595 221125_WJC_METTL3_EV_vs_WT_F03.17944.17944.3 0.231 Aug-36 R.DLEEKLETLR.L "sp|Q14203|DCTN1_HUMAN,tr|A0A804CDA6|A0A804CDA6_HUMAN,tr|E7EX90|E7EX90_HUMAN,tr|A0A7P0Z4C3|A0A7P0Z4C3_HUMAN,tr|Q6AWB1|Q6AWB1_HUMAN" 5 1244.6612 1.79 33124 17944 3 1244.658251 415.8944 Dynactin subunit 1 OS=Homo sapiens OX=9606 GN=DCTN1 PE=1 SV=3 4.41 3089.7 - 2.53E+06 - - - -2.395 - 1.498 0.241 - 90 1 2 1 -0.003 10 0 0 0 2.74E+07 1.53E+07 - - - 2.4063 0.9999 221125_WJC_METTL3_EV_vs_WT_F03.17949.17949.2 1.79E-05 24-Nov R.LLEVQSQVEELQK.S sp|Q86VS8|HOOK3_HUMAN 1 1541.8301 999 33129 17949 2 1541.830025 771.9223 Protein Hook homolog 3 OS=Homo sapiens OX=9606 GN=HOOK3 PE=1 SV=2 4.25 3090.3 - 548770 - - - -0.0409 - 2.599 0.41 - 360.5 1 2 0 -0.0001 13 0 0 0 2.64E+07 0.00E+00 - - - 4.5206 1 221125_WJC_METTL3_EV_vs_WT_F03.17951.17951.2 2.59E-07 15/34 K.PSTASAVPELATDPELEK.K "sp|Q86U44|MTA70_HUMAN,tr|B4E349|B4E349_HUMAN,tr|F5H6D8|F5H6D8_HUMAN,tr|H0YFV6|H0YFV6_HUMAN,tr|B4DTN4|B4DTN4_HUMAN" 5 1853.9258 0.03 33130 17951 2 1854.925259 927.9702 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 4 3090.5 - 8.98E+06 - - - 539.0831 - 2.849 0.603 - 416.3 1 1 0 0.9994 18 0 0 0 2.29E+08 7.76E+09 - - - 5.755 1 221125_WJC_METTL3_EV_vs_WT_F03.17953.17953.3 2.93E-05 13/44 R.KSEIEYYAMLAK.T "sp|P62888|RL30_HUMAN,tr|E5RI99|E5RI99_HUMAN" 2 1444.7272 1.24 33132 17953 3 1444.724914 482.583 60S ribosomal protein L30 OS=Homo sapiens OX=9606 GN=RPL30 PE=1 SV=2 6.14 3090.6 - 6.28E+06 - - - -1.5844 - 2.597 0.502 - 174.6 1 2 0 -0.0023 12 0 0 0 1.71E+08 1.38E+08 - - - 6.7815 0.9999 221125_WJC_METTL3_EV_vs_WT_F03.17954.17954.3 0.000229 13/44 R.K[136.11]SEIEYYAMLAK[136.11].T "sp|P62888|RL30_HUMAN,tr|E5RI99|E5RI99_HUMAN" 2 1460.7556 1.22 33133 17954 3 1460.752793 487.9258 60S ribosomal protein L30 OS=Homo sapiens OX=9606 GN=RPL30 PE=1 SV=2 6.14 3090.7 - 6.19E+06 - - - -1.9237 - 2.273 0.48 - 179 1 2 0 -0.0028 12 0 0 0 1.69E+08 1.38E+08 - - - 6.1667 0.9996 221125_WJC_METTL3_EV_vs_WT_F03.17955.17955.2 2.45E-08 16-Oct R.YNFFTGC[160.03]PK.A sp|Q99832|TCPH_HUMAN 1 1132.5012 0.24 33134 17955 2 1132.497604 567.2579 T-complex protein 1 subunit eta OS=Homo sapiens OX=9606 GN=CCT7 PE=1 SV=2 8.2 3090.8 - 1.98E+06 - - - -3.1453 - 2.059 0.598 - 352.3 1 2 0 -0.0036 9 0 0 0 6.47E+07 2.71E+08 - - - 5.5461 1 221125_WJC_METTL3_EV_vs_WT_F03.17956.17956.2 2.48E-11 20/22 R.K[136.11]SEIEYYAMLAK[136.11].T "sp|P62888|RL30_HUMAN,tr|E5RI99|E5RI99_HUMAN" 2 1460.7556 2.34 33135 17956 2 1460.7515 731.3851 60S ribosomal protein L30 OS=Homo sapiens OX=9606 GN=RPL30 PE=1 SV=2 6.14 3090.9 - 1.78E+06 - - - -2.8088 - 3.594 0.622 - 1517.9 1 2 0 -0.0041 12 0 0 0 9.71E+07 4.15E+07 - - - 6.9998 0.9998 221125_WJC_METTL3_EV_vs_WT_F03.17957.17957.3 0.00048 19/60 K.LYDLYIEEC[160.03]EKEPEVK.K "sp|Q8NEM7|SP20H_HUMAN,tr|B4E2D5|B4E2D5_HUMAN,tr|R4GND2|R4GND2_HUMAN,tr|F6S7C4|F6S7C4_HUMAN,tr|C9JQS2|C9JQS2_HUMAN" 5 2055.9711 1.02 33136 17957 3 2055.965691 686.331 Transcription factor SPT20 homolog OS=Homo sapiens OX=9606 GN=SUPT20H PE=1 SV=2 4.14 3091 - 1.15E+06 - - - -2.6187 - 3.256 0.552 - 398.2 1 2 1 -0.0054 16 0 0 0 9.42E+06 9.23E+06 - - - 7.7218 0.9961 221125_WJC_METTL3_EV_vs_WT_F03.17959.17959.2 0.000265 20-Dec K.WIDPEQLSNPK[136.11].K sp|O95409|ZIC2_HUMAN 1 1333.6758 2.67 33138 17959 2 1333.669244 667.8452 Zinc finger protein ZIC 2 OS=Homo sapiens OX=9606 GN=ZIC2 PE=1 SV=2 4.37 3091.3 - 842024 - - - -4.8902 - 2.077 0.397 - 454.6 1 2 0 -0.0065 11 0 0 0 4.50E+07 1.69E+07 - - - 3.9485 1 221125_WJC_METTL3_EV_vs_WT_F03.17962.17962.2 1.16E-08 15/22 R.YLYTLVITDKEK.A "sp|P63173|RL38_HUMAN,tr|J3KT73|J3KT73_HUMAN,tr|J3QL01|J3QL01_HUMAN" 3 1484.8126 1.1 33139 17962 2 1484.809321 743.4136 60S ribosomal protein L38 OS=Homo sapiens OX=9606 GN=RPL38 PE=1 SV=2 6.07 3091.7 - 1.25E+07 - - - -2.24 - 2.836 0.625 - 756.2 1 2 1 -0.0033 12 0 0 0 8.58E+08 7.83E+08 - - - 6.3989 0.9998 221125_WJC_METTL3_EV_vs_WT_F03.17964.17964.2 5.76E-05 16-Sep R.DDNMFQIGK.M sp|P53999|TCP4_HUMAN 1 1066.4753 0.37 33141 17964 2 1066.4739 534.2449 Activated RNA polymerase II transcriptional coactivator p15 OS=Homo sapiens OX=9606 GN=SUB1 PE=1 SV=3 4.21 3091.8 - 3.43E+06 - - - -1.3549 - 1.859 0.47 - 354.3 1 2 0 -0.0014 9 0 0 0 5.22E+07 1.42E+08 - - - 4.3058 0.9997 221125_WJC_METTL3_EV_vs_WT_F03.17965.17965.3 3.53E-05 15/44 R.YLYTLVITDKEK[136.11].A "sp|P63173|RL38_HUMAN,tr|J3KT73|J3KT73_HUMAN,tr|J3QL01|J3QL01_HUMAN" 3 1492.8268 - 33142 17965 3 1492.823627 498.6162 60S ribosomal protein L38 OS=Homo sapiens OX=9606 GN=RPL38 PE=1 SV=2 6.07 3091.9 - 2.52E+06 - - - -2.157 - 2.271 0.499 - 164 1 2 1 -0.0032 12 0 0 0 - - - - - 6.376 1 221125_WJC_METTL3_EV_vs_WT_F03.17966.17966.3 1.04E-07 16/48 R.EAYPGDVFYLHSR.L sp|P25705|ATPA_HUMAN 1 1552.731 1.71 33143 17966 3 1552.732945 518.5843 "ATP synthase subunit alpha, mitochondrial OS=Homo sapiens OX=9606 GN=ATP5F1A PE=1 SV=1" 5.32 3092 - 2.32E+06 - - - 1.2249 - 2.665 0.475 - 238.2 1 2 0 0.0019 13 0 0 0 3.37E+08 1.98E+08 - - - 6.4929 0.8989 221125_WJC_METTL3_EV_vs_WT_F03.17967.17967.2 0.00187 18-Dec L.YTLVITDKEK.A "sp|P63173|RL38_HUMAN,tr|J3KT73|J3KT73_HUMAN,tr|J3QL01|J3QL01_HUMAN" 3 1208.6653 1.12 33144 17967 2 1208.665753 605.3399 60S ribosomal protein L38 OS=Homo sapiens OX=9606 GN=RPL38 PE=1 SV=2 6.07 3092.1 - 1.98E+06 - - - 0.412 - 2.163 0.438 - 557.2 1 1 1 0.0005 10 0 0 0 1.28E+08 1.14E+08 - - - 4.4294 0.9991 221125_WJC_METTL3_EV_vs_WT_F03.17969.17969.2 0.00175 18-Sep R.LQIFSVEGQK[136.11].A "sp|A6NHR9|SMHD1_HUMAN,tr|J3KTL8|J3KTL8_HUMAN" 2 1155.6379 0.59 33146 17969 2 1155.640481 578.8262 Structural maintenance of chromosomes flexible hinge domain-containing protein 1 OS=Homo sapiens OX=9606 GN=SMCHD1 PE=1 SV=2 6 3092.4 - 1.57E+06 - - - 2.2126 - 1.733 0.396 - 218.6 1 2 0 0.0026 10 0 0 0 2.90E+07 4.89E+07 - - - 3.4999 0.9997 221125_WJC_METTL3_EV_vs_WT_F03.17973.17973.2 0.0566 18-Sep K.IQLEQVQEWK.S "sp|Q14203|DCTN1_HUMAN,tr|A0A804CDA6|A0A804CDA6_HUMAN,tr|E7EX90|E7EX90_HUMAN,tr|A0A7P0Z4C3|A0A7P0Z4C3_HUMAN,tr|Q6AWB1|Q6AWB1_HUMAN" 5 1299.6823 2.16 33149 17973 2 1299.68063 650.8484 Dynactin subunit 1 OS=Homo sapiens OX=9606 GN=DCTN1 PE=1 SV=3 4.53 3092.8 - 1.51E+07 - - - -1.2865 - 1.953 0.408 - 349.9 1 2 0 -0.0017 10 0 0 0 2.44E+08 1.13E+08 - - - 3.9224 0.8954 221125_WJC_METTL3_EV_vs_WT_F03.17975.17975.2 0.000214 18-Dec L.YTLVITDK[136.11]EK[136.11].A "sp|P63173|RL38_HUMAN,tr|J3KT73|J3KT73_HUMAN,tr|J3QL01|J3QL01_HUMAN" 3 1224.6937 1.12 33150 17975 2 1224.692758 613.3541 60S ribosomal protein L38 OS=Homo sapiens OX=9606 GN=RPL38 PE=1 SV=2 6.07 3093.1 - 5.16E+06 - - - -0.7324 - 2.108 0.444 - 684.1 1 1 1 -0.0009 10 0 0 0 1.28E+08 1.14E+08 - - - 4.4017 1 221125_WJC_METTL3_EV_vs_WT_F03.17976.17976.3 0.000325 18/48 R.EAYPGDVFYLHSR[166.11].L sp|P25705|ATPA_HUMAN 1 1562.7393 1.72 33151 17976 3 1562.739755 521.9204 "ATP synthase subunit alpha, mitochondrial OS=Homo sapiens OX=9606 GN=ATP5F1A PE=1 SV=1" 5.32 3093.1 - 2.69E+06 - - - 0.2828 - 2.672 0.491 - 357 1 2 0 0.0004 13 0 0 0 3.39E+08 1.98E+08 - - - 6.6788 0.9994 221125_WJC_METTL3_EV_vs_WT_F03.17977.17977.2 0.00694 18-Oct K.IQLEQVQEWK[136.11].S "sp|Q14203|DCTN1_HUMAN,tr|A0A804CDA6|A0A804CDA6_HUMAN,tr|E7EX90|E7EX90_HUMAN,tr|A0A7P0Z4C3|A0A7P0Z4C3_HUMAN,tr|Q6AWB1|Q6AWB1_HUMAN" 5 1307.6965 2.16 33152 17977 2 1307.694857 654.8555 Dynactin subunit 1 OS=Homo sapiens OX=9606 GN=DCTN1 PE=1 SV=3 4.53 3093.2 - 9.80E+06 - - - -1.2579 - 2.026 0.299 - 454 1 2 0 -0.0016 10 0 0 0 2.44E+08 1.13E+08 - - - 3.2197 1 221125_WJC_METTL3_EV_vs_WT_F03.17978.17978.3 6.44E-10 24/80 R.VTGEADVEFATHEDAVAAMAK.D sp|P55795|HNRH2_HUMAN 1 2160.9997 1.34 33153 17978 3 2160.994829 721.3405 Heterogeneous nuclear ribonucleoprotein H2 OS=Homo sapiens OX=9606 GN=HNRNPH2 PE=1 SV=1 4.17 3093.2 - 6.37E+06 - - - -2.2767 - 4.783 0.682 - 691.4 1 2 0 -0.0049 21 0 0 0 1.15E+08 8.57E+07 - - - 9.8944 1 221125_WJC_METTL3_EV_vs_WT_F03.17981.17981.2 3.04E-11 18/30 R.EEFGAEPELAVSAPGR.V "sp|P51570|GALK1_HUMAN,tr|K7ERJ9|K7ERJ9_HUMAN,tr|K7ERN9|K7ERN9_HUMAN,tr|K7EII7|K7EII7_HUMAN" 4 1657.7948 1.8 33156 17981 2 1657.794842 829.9047 Galactokinase OS=Homo sapiens OX=9606 GN=GALK1 PE=1 SV=1 4.09 3093.6 - 1.44E+06 - - - 0.0464 - 3.241 0.549 - 750.4 1 2 0 0.0001 16 0 0 0 6.01E+07 3.34E+07 - - - 5.9868 0.9998 221125_WJC_METTL3_EV_vs_WT_F03.17987.17987.2 0.00043 18-Nov R.FNVPVSLESK.K "sp|P82979|SARNP_HUMAN,tr|F8VZQ9|F8VZQ9_HUMAN,tr|H0YHG0|H0YHG0_HUMAN" 3 1118.5972 0.5 33161 17987 2 1118.597455 560.3059 SAP domain-containing ribonucleoprotein OS=Homo sapiens OX=9606 GN=SARNP PE=1 SV=3 6 3094.3 - 1.60E+06 - - - 0.2503 - 2.16 0.448 - 388.7 1 2 0 0.0003 10 0 0 0 5.79E+07 1.17E+08 - - - 4.4994 0.9029 221125_WJC_METTL3_EV_vs_WT_F03.17989.17989.2 3.22E-07 14/20 Y.LYTLVITDK[136.11]EK[136.11].A "sp|P63173|RL38_HUMAN,tr|J3KT73|J3KT73_HUMAN,tr|J3QL01|J3QL01_HUMAN" 3 1337.7777 1.2 33162 17989 2 1337.776231 669.8961 60S ribosomal protein L38 OS=Homo sapiens OX=9606 GN=RPL38 PE=1 SV=2 6.07 3094.5 - 2.99E+06 - - - -1.1123 - 2.714 0.41 - 811.9 1 1 1 -0.0015 11 0 0 0 5.54E+07 4.61E+07 - - - 4.7698 0.9999 221125_WJC_METTL3_EV_vs_WT_F03.17990.17990.2 6.86E-06 13/20 K.EIQGFLDC[160.03]AAR[166.11].A "sp|Q96BP2|CHCH1_HUMAN,tr|A6NJX6|A6NJX6_HUMAN" 2 1288.6109 0.82 33163 17990 2 1288.609423 645.3127 Coiled-coil-helix-coiled-coil-helix domain-containing protein 1 OS=Homo sapiens OX=9606 GN=CHCHD1 PE=1 SV=1 4.37 3094.6 - 2.75E+06 - - - -1.178 - 2.538 0.515 - 735.7 1 2 0 -0.0015 11 0 0 0 7.45E+07 9.14E+07 - - - 5.3639 0.9997 221125_WJC_METTL3_EV_vs_WT_F03.17992.17992.2 0.000393 16-Nov K.AAVEWFDGK[136.11].D "sp|Q01844|EWS_HUMAN,tr|B0QYK0|B0QYK0_HUMAN,tr|H7BY36|H7BY36_HUMAN,tr|A0A0D9SFL3|A0A0D9SFL3_HUMAN,tr|C9JGE3|C9JGE3_HUMAN" 5 1029.5011 0.65 33165 17992 2 1029.49935 515.7578 RNA-binding protein EWS OS=Homo sapiens OX=9606 GN=EWSR1 PE=1 SV=1 4.37 3094.8 - 2.68E+06 - - - -1.696 - 2.109 0.443 - 435 1 2 0 -0.0017 9 0 0 0 5.10E+07 7.84E+07 - - - 4.4713 0.9878 221125_WJC_METTL3_EV_vs_WT_F03.17993.17993.3 0.000116 Oct-40 K.EHLYFETVTIK.L "sp|Q15155|NOMO1_HUMAN,sp|Q5JPE7|NOMO2_HUMAN,sp|P69849|NOMO3_HUMAN,tr|A0A7I2V3P4|A0A7I2V3P4_HUMAN,tr|A0A7I2V6B0|A0A7I2V6B0_HUMAN,tr|A0A7I2V4D7|A0A7I2V4D7_HUMAN,tr|A0A7I2V4T6|A0A7I2V4T6_HUMAN,tr|A0A0G2JP90|A0A0G2JP90_HUMAN,tr|A0A087X117|A0A087X117_HUMAN,tr|A0A0G2JN29|A0A0G2JN29_HUMAN,tr|A0A7I2V2Z5|A0A7I2V2Z5_HUMAN,tr|A0A087WW46|A0A087WW46_HUMAN,tr|J3KN36|J3KN36_HUMAN" 13 1378.7133 1.28 33166 17993 3 1378.706562 460.5784 Nodal modulator 1 OS=Homo sapiens OX=9606 GN=NOMO1 PE=1 SV=5 5.4 3094.9 - 1.70E+06 - - - -4.8632 - 1.901 0.275 - 119.9 1 2 0 -0.0067 11 0 0 0 3.08E+07 2.41E+07 - - - 3.429 1 221125_WJC_METTL3_EV_vs_WT_F03.17995.17995.2 1.54E-09 19/32 R.VIGLSSDLQQVGGASAR[166.11].L "sp|O00303|EIF3F_HUMAN,tr|H0YDT6|H0YDT6_HUMAN" 2 1666.8878 1 33168 17995 2 1666.883761 834.4512 Eukaryotic translation initiation factor 3 subunit F OS=Homo sapiens OX=9606 GN=EIF3F PE=1 SV=1 5.81 3095.2 - 1.17E+06 - - - -2.4039 - 3.037 0.627 - 1018.1 1 2 0 -0.004 17 0 0 0 4.06E+07 4.06E+07 - - - 6.4019 0.9495 221125_WJC_METTL3_EV_vs_WT_F03.17996.17996.2 0.274 20-Aug R.GGIVDEGALLR.A "sp|O43175|SERA_HUMAN,tr|A0A286YF78|A0A286YF78_HUMAN,tr|A0A2C9F2M7|A0A2C9F2M7_HUMAN,tr|A0A286YF22|A0A286YF22_HUMAN,tr|A0A286YFL2|A0A286YFL2_HUMAN,tr|A0A286YFA2|A0A286YFA2_HUMAN,tr|A0A286YFM8|A0A286YFM8_HUMAN" 7 1098.6033 1.55 33169 17996 2 1098.598474 550.3089 D-3-phosphoglycerate dehydrogenase OS=Homo sapiens OX=9606 GN=PHGDH PE=1 SV=4 4.37 3095.3 - 1.10E+06 - - - -4.4138 - 1.34 0.189 - 89.4 1 2 0 -0.0048 11 0 0 0 2.10E+07 1.36E+07 - - - 1.2272 0.9996 221125_WJC_METTL3_EV_vs_WT_F03.17999.17999.2 8.61E-05 16-Aug R.DNWVFC[160.03]GGK.G sp|Q92520|FAM3C_HUMAN 1 1081.4651 1.1 33170 17999 2 1081.463646 541.7398 Protein FAM3C OS=Homo sapiens OX=9606 GN=FAM3C PE=1 SV=1 5.83 3095.7 - 3.07E+06 - - - -1.3583 - 1.539 0.456 - 262.6 1 2 0 -0.0015 9 0 0 0 5.16E+07 4.71E+07 - - - 3.6558 0.9992 221125_WJC_METTL3_EV_vs_WT_F03.18000.18000.2 0.00412 16-Aug R.DNWVFC[160.03]GGK[136.11].G sp|Q92520|FAM3C_HUMAN 1 1089.4793 1.1 33171 18000 2 1089.476896 545.7469 Protein FAM3C OS=Homo sapiens OX=9606 GN=FAM3C PE=1 SV=1 5.83 3095.8 - 2.91E+06 - - - -2.2203 - 1.721 0.394 - 250.6 1 2 0 -0.0024 9 0 0 0 5.16E+07 4.71E+07 - - - 3.521 0.9988 221125_WJC_METTL3_EV_vs_WT_F03.18001.18001.3 0.000253 19/64 R.VIGLSSDLQQVGGASAR[166.11].L "sp|O00303|EIF3F_HUMAN,tr|H0YDT6|H0YDT6_HUMAN" 2 1666.8878 1.11 33172 18001 3 1666.877981 556.6365 Eukaryotic translation initiation factor 3 subunit F OS=Homo sapiens OX=9606 GN=EIF3F PE=1 SV=1 5.81 3095.9 - 1.43E+06 - - - -5.8714 - 3.138 0.425 - 305.2 1 2 0 -0.0098 17 0 0 0 3.30E+07 2.98E+07 - - - 6.1647 0.9467 221125_WJC_METTL3_EV_vs_WT_F03.18004.18004.2 2.52E-05 20-Dec K.ESAAINQILGR[166.11].R "sp|P36402|TCF7_HUMAN,sp|Q9UJU2|LEF1_HUMAN,sp|Q9HCS4|TF7L1_HUMAN,sp|Q9NQB0|TF7L2_HUMAN,tr|A0A0A0MTL7|A0A0A0MTL7_HUMAN,tr|Q5VVR7|Q5VVR7_HUMAN,tr|Q5JRY3|Q5JRY3_HUMAN,tr|E2GH26|E2GH26_HUMAN,tr|Q5JRY5|Q5JRY5_HUMAN,tr|H0YAR8|H0YAR8_HUMAN,tr|C6ZRK5|C6ZRK5_HUMAN,tr|H0YBP2|H0YBP2_HUMAN,tr|B7WNT5|B7WNT5_HUMAN,tr|C6ZRJ6|C6ZRJ6_HUMAN,tr|C6ZRJ7|C6ZRJ7_HUMAN,tr|H0YEE5|H0YEE5_HUMAN,tr|H0YBC8|H0YBC8_HUMAN,tr|A0A1B0GUV5|A0A1B0GUV5_HUMAN,tr|A0A0D9SGH8|A0A0D9SGH8_HUMAN" 19 1180.644 3 33175 18004 2 1181.642703 591.3293 Transcription factor 7 OS=Homo sapiens OX=9606 GN=TCF7 PE=1 SV=3 6.1 3096.3 - 909804 - - - 845.9341 - 2.531 0.43 - 500.2 1 2 0 0.9987 11 0 0 0 4.03E+07 1.34E+07 - - - 4.4155 0.9995 221125_WJC_METTL3_EV_vs_WT_F03.18008.18008.2 0.00053 16-Sep K.AAVEWFDGK.D "sp|Q01844|EWS_HUMAN,tr|B0QYK0|B0QYK0_HUMAN,tr|H7BY36|H7BY36_HUMAN,tr|A0A0D9SFL3|A0A0D9SFL3_HUMAN,tr|C9JGE3|C9JGE3_HUMAN" 5 1021.4869 0.65 33177 18008 2 1021.484591 511.7507 RNA-binding protein EWS OS=Homo sapiens OX=9606 GN=EWSR1 PE=1 SV=1 4.37 3096.7 - 2.94E+06 - - - -2.2565 - 1.899 0.442 - 290.5 1 2 0 -0.0023 9 0 0 0 5.08E+07 7.79E+07 - - - 4.1603 0.9939 221125_WJC_METTL3_EV_vs_WT_F03.18009.18009.3 0.0671 16/64 R.VIGLSSDLQQVGGASAR.L "sp|O00303|EIF3F_HUMAN,tr|H0YDT6|H0YDT6_HUMAN" 2 1656.8795 1.12 33178 18009 3 1656.878641 553.3004 Eukaryotic translation initiation factor 3 subunit F OS=Homo sapiens OX=9606 GN=EIF3F PE=1 SV=1 5.81 3096.8 - 2.65E+06 - - - -0.5172 - 1.719 0.197 - 232.5 1 2 0 -0.0009 17 0 0 0 3.30E+07 2.94E+07 - - - 2.1047 0.9999 221125_WJC_METTL3_EV_vs_WT_F03.18013.18013.2 1.18E-06 14/20 K.ESAAINQILGR[166.11].R "sp|P36402|TCF7_HUMAN,sp|Q9UJU2|LEF1_HUMAN,sp|Q9HCS4|TF7L1_HUMAN,sp|Q9NQB0|TF7L2_HUMAN,tr|A0A0A0MTL7|A0A0A0MTL7_HUMAN,tr|Q5VVR7|Q5VVR7_HUMAN,tr|Q5JRY3|Q5JRY3_HUMAN,tr|E2GH26|E2GH26_HUMAN,tr|Q5JRY5|Q5JRY5_HUMAN,tr|H0YAR8|H0YAR8_HUMAN,tr|C6ZRK5|C6ZRK5_HUMAN,tr|H0YBP2|H0YBP2_HUMAN,tr|B7WNT5|B7WNT5_HUMAN,tr|C6ZRJ6|C6ZRJ6_HUMAN,tr|C6ZRJ7|C6ZRJ7_HUMAN,tr|H0YEE5|H0YEE5_HUMAN,tr|H0YBC8|H0YBC8_HUMAN,tr|A0A1B0GUV5|A0A1B0GUV5_HUMAN,tr|A0A0D9SGH8|A0A0D9SGH8_HUMAN" 19 1180.644 3 33182 18013 2 1180.643565 591.3293 Transcription factor 7 OS=Homo sapiens OX=9606 GN=TCF7 PE=1 SV=3 6.1 3097.3 - 1.23E+06 - - - -0.3312 - 2.781 0.451 - 733.3 1 2 0 -0.0004 11 0 0 0 4.03E+07 1.34E+07 - - - 5.1389 1 221125_WJC_METTL3_EV_vs_WT_F03.18021.18021.2 1.80E-07 13/20 R.C[160.03]TYLVLDEADR[166.11].M "sp|Q92841|DDX17_HUMAN,tr|A0A5H1ZRQ2|A0A5H1ZRQ2_HUMAN,tr|A0A1X7SBZ2|A0A1X7SBZ2_HUMAN" 3 1363.6317 2.22 33188 18021 2 1363.627343 682.8231 Probable ATP-dependent RNA helicase DDX17 OS=Homo sapiens OX=9606 GN=DDX17 PE=1 SV=2 4.03 3098.3 - 2.19E+06 - - - -3.2215 - 2.539 0.603 - 955.9 1 2 0 -0.0044 11 0 0 0 7.02E+07 3.16E+07 - - - 6.014 0.9994 221125_WJC_METTL3_EV_vs_WT_F03.18022.18022.2 0.0116 16-Oct R.SPSWYGIPR[166.11].L "sp|P78347|GTF2I_HUMAN,tr|A0A494C0Q7|A0A494C0Q7_HUMAN,tr|A0A494C1K3|A0A494C1K3_HUMAN" 3 1071.5377 1.37 33189 18022 2 1071.536147 536.7761 General transcription factor II-I OS=Homo sapiens OX=9606 GN=GTF2I PE=1 SV=2 8.46 3098.4 - 1.58E+06 - - - -1.4493 - 1.863 0.327 - 614.6 1 2 0 -0.0016 9 0 0 0 6.05E+07 4.43E+07 - - - 3.2558 1 221125_WJC_METTL3_EV_vs_WT_F03.18024.18024.2 9.92E-10 15/28 K.GYAYVEFENPDEAEK[136.11].A "sp|Q15287|RNPS1_HUMAN,tr|H3BMM9|H3BMM9_HUMAN,tr|H3BV80|H3BV80_HUMAN,tr|H3BMS0|H3BMS0_HUMAN,tr|H3BTC0|H3BTC0_HUMAN,tr|H3BPG5|H3BPG5_HUMAN" 6 1767.7719 1.69 33191 18024 2 1767.764213 884.8932 RNA-binding protein with serine-rich domain 1 OS=Homo sapiens OX=9606 GN=RNPS1 PE=1 SV=1 3.91 3098.7 - 1.07E+06 - - - -4.3546 - 3.045 0.691 - 742.5 1 2 0 -0.0077 15 0 0 0 1.20E+08 7.08E+07 - - - 6.8799 1 221125_WJC_METTL3_EV_vs_WT_F03.18025.18025.2 2.50E-07 16/28 K.SLDIGNQMNVSEEMK.V "sp|Q6P3W7|SCYL2_HUMAN,tr|F8VSC5|F8VSC5_HUMAN,tr|A0A0U1RQQ9|A0A0U1RQQ9_HUMAN" 3 1693.7651 3.31 33192 18025 2 1693.758305 847.8898 SCY1-like protein 2 OS=Homo sapiens OX=9606 GN=SCYL2 PE=1 SV=1 4.14 3098.8 - 1.04E+06 - - - -4.0242 - 2.727 0.619 - 401 1 2 0 -0.0068 15 0 0 0 1.16E+07 3.51E+06 - - - 6.0772 1 221125_WJC_METTL3_EV_vs_WT_F03.18030.18030.2 5.00E-09 24-Dec R.QVQSLTC[160.03]EVDALK.G "sp|P08670|VIME_HUMAN,tr|B0YJC5|B0YJC5_HUMAN,tr|B0YJC4|B0YJC4_HUMAN" 3 1489.7446 1.85 33195 18030 2 1489.741592 745.8796 Vimentin OS=Homo sapiens OX=9606 GN=VIM PE=1 SV=4 4.37 3099.4 - 4.43E+06 - - - -2.0487 - 2.425 0.615 - 480.9 1 2 0 -0.0031 13 0 0 0 1.57E+09 8.47E+08 - - - 5.8559 0.9999 221125_WJC_METTL3_EV_vs_WT_F03.18031.18031.2 2.72E-06 13/24 K.LGEMWNNLNDSEK[136.11].Q "sp|O15347|HMGB3_HUMAN,tr|E9PES6|E9PES6_HUMAN,tr|E7EQU1|E7EQU1_HUMAN,tr|E7ES08|E7ES08_HUMAN" 4 1556.7021 0.1 33196 18031 2 1556.699606 779.3583 High mobility group protein B3 OS=Homo sapiens OX=9606 GN=HMGB3 PE=1 SV=4 4.14 3099.5 - 1.82E+06 - - - -1.5745 - 2.645 0.543 - 626.5 1 2 0 -0.0025 13 0 0 0 2.29E+06 2.32E+07 - - - 5.5472 1 221125_WJC_METTL3_EV_vs_WT_F03.18033.18033.2 4.16E-05 15/20 Y.LYTLVITDKEK.A "sp|P63173|RL38_HUMAN,tr|J3KT73|J3KT73_HUMAN,tr|J3QL01|J3QL01_HUMAN" 3 1321.7493 1.2 33198 18033 2 1321.747542 661.8819 60S ribosomal protein L38 OS=Homo sapiens OX=9606 GN=RPL38 PE=1 SV=2 6.07 3099.6 - 2.15E+06 - - - -1.3444 - 2.919 0.524 - 1012.3 1 1 1 -0.0018 11 0 0 0 5.54E+07 4.61E+07 - - - 5.8087 0.9969 221125_WJC_METTL3_EV_vs_WT_F03.18034.18034.2 4.73E-05 18-Aug R.EYFGQFGEVK.E sp|O43347|MSI1H_HUMAN 1 1202.5608 0.71 33199 18034 2 1202.554918 602.2877 RNA-binding protein Musashi homolog 1 OS=Homo sapiens OX=9606 GN=MSI1 PE=1 SV=1 4.53 3099.6 - 2.00E+06 - - - -4.8821 - 1.478 0.559 - 181.8 1 2 0 -0.0059 10 0 0 0 3.70E+07 5.25E+07 - - - 4.2585 1 221125_WJC_METTL3_EV_vs_WT_F03.18035.18035.2 7.75E-11 15/28 K.GYAYVEFENPDEAEK.A "sp|Q15287|RNPS1_HUMAN,tr|H3BMM9|H3BMM9_HUMAN,tr|H3BV80|H3BV80_HUMAN,tr|H3BMS0|H3BMS0_HUMAN,tr|H3BTC0|H3BTC0_HUMAN,tr|H3BPG5|H3BPG5_HUMAN" 6 1759.7577 1.69 33200 18035 2 1759.753186 880.8861 RNA-binding protein with serine-rich domain 1 OS=Homo sapiens OX=9606 GN=RNPS1 PE=1 SV=1 3.91 3099.8 - 1.71E+06 - - - -2.5714 - 3.169 0.697 - 765.6 1 2 0 -0.0045 15 0 0 0 1.20E+08 7.08E+07 - - - 7.0233 0.9997 221125_WJC_METTL3_EV_vs_WT_F03.18036.18036.2 3.01E-06 13/22 R.WLTIQSGEQPYK[136.11].M sp|O43920|NDUS5_HUMAN 1 1456.7442 1.32 33201 18036 2 1456.740668 729.3794 NADH dehydrogenase [ubiquinone] iron-sulfur protein 5 OS=Homo sapiens OX=9606 GN=NDUFS5 PE=1 SV=3 6 3099.9 - 1.49E+06 - - - -2.4109 - 2.581 0.504 - 505.3 1 2 0 -0.0035 12 0 0 0 3.34E+07 2.53E+07 - - - 5.2573 0.9997 221125_WJC_METTL3_EV_vs_WT_F03.18041.18041.2 0.000439 18-Jul R.SWNGSVEILK.N "sp|Q08188|TGM3_HUMAN,tr|A0A494C0J7|A0A494C0J7_HUMAN" 2 1131.5924 14.09 33204 18041 2 1131.592035 566.8035 Protein-glutamine gamma-glutamyltransferase E OS=Homo sapiens OX=9606 GN=TGM3 PE=1 SV=4 5.72 3100.5 - 3.25E+06 - - - -0.3438 - 1.63 0.426 - 139 1 2 0 -0.0004 10 0 0 0 6.06E+07 4.30E+06 - - - 3.5511 0.9305 221125_WJC_METTL3_EV_vs_WT_F03.18042.18042.3 0.000495 Oct-60 K.R[166.11]GLLQDDAHPTLVTYA.D "sp|Q86U44|MTA70_HUMAN,tr|F5H6D8|F5H6D8_HUMAN,tr|H0YFV6|H0YFV6_HUMAN,tr|B4DTN4|B4DTN4_HUMAN" 4 1778.9191 0.07 33205 18042 3 1778.915247 593.9803 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 5.21 3100.5 - 2.77E+06 - - - -2.1479 - 1.888 0.352 - 82.4 1 1 0 -0.0038 16 0 0 0 1.97E+06 2.73E+07 - - - 4.094 0.9998 221125_WJC_METTL3_EV_vs_WT_F03.18043.18043.2 8.24E-06 24-Oct K.LFIGGLNTETNEK[136.11].A "sp|Q96E39|RMXL1_HUMAN,sp|P38159|RBMX_HUMAN,tr|A0A1B0GUK8|A0A1B0GUK8_HUMAN,tr|H3BT71|H3BT71_HUMAN,tr|H0Y6E7|H0Y6E7_HUMAN,tr|H3BR27|H3BR27_HUMAN,tr|H3BNC1|H3BNC1_HUMAN" 7 1442.7497 1.5 33206 18043 2 1442.747028 722.3821 "RNA binding motif protein, X-linked-like-1 OS=Homo sapiens OX=9606 GN=RBMXL1 PE=1 SV=1" 4.53 3100.6 - 6.96E+06 - - - -1.8236 - 2.157 0.504 - 201.5 1 2 0 -0.0026 13 0 0 0 1.67E+09 1.11E+09 - - - 4.7357 0.9989 221125_WJC_METTL3_EV_vs_WT_F03.18044.18044.2 0.000464 13/22 R.ELAQQIEEETIK.F sp|Q9BUQ8|DDX23_HUMAN 1 1429.73 0.32 33207 18044 2 1429.724697 715.8723 Probable ATP-dependent RNA helicase DDX23 OS=Homo sapiens OX=9606 GN=DDX23 PE=1 SV=3 4.09 3100.6 - 2.37E+06 - - - -3.7371 - 2.375 0.435 - 546 1 2 0 -0.0053 12 0 0 0 2.43E+07 7.55E+07 - - - 4.5282 0.9998 221125_WJC_METTL3_EV_vs_WT_F03.18045.18045.2 0.00773 24-Dec R.EAYPGDVFYLHSR.L sp|P25705|ATPA_HUMAN 1 1552.731 4.65 33208 18045 2 1552.731491 777.3728 "ATP synthase subunit alpha, mitochondrial OS=Homo sapiens OX=9606 GN=ATP5F1A PE=1 SV=1" 5.32 3100.7 - 1.78E+06 - - - 0.2885 - 2.217 0.466 - 373.8 1 2 0 0.0004 13 0 0 0 3.95E+07 8.49E+06 - - - 4.5261 0.9992 221125_WJC_METTL3_EV_vs_WT_F03.18046.18046.2 5.11E-06 20-Nov K.SGEEDEEILFK[136.11].E sp|P49792|RBP2_HUMAN 1 1302.6071 2.12 33209 18046 2 1302.602155 652.3108 E3 SUMO-protein ligase RanBP2 OS=Homo sapiens OX=9606 GN=RANBP2 PE=1 SV=2 3.91 3100.9 - 1.22E+06 - - - -3.7793 - 2.411 0.496 - 579.2 1 2 0 -0.0049 11 0 0 0 3.71E+07 1.75E+07 - - - 5.0836 0.998 221125_WJC_METTL3_EV_vs_WT_F03.18047.18047.2 0.391 22-Aug R.GSIIISPC[160.03]VVC[160.03]R[166.11].G sp|Q96EY1|DNJA3_HUMAN 1 1369.7085 0.63 33210 18047 2 1369.708119 685.8615 "DnaJ homolog subfamily A member 3, mitochondrial OS=Homo sapiens OX=9606 GN=DNAJA3 PE=1 SV=2" 8.07 3101 - 1.13E+06 - - - -0.3125 - 1.95 0.152 - 238.5 2 2 0 -0.0004 12 0 0 0 1.63E+07 2.59E+07 - - - 1.7862 0.9999 221125_WJC_METTL3_EV_vs_WT_F03.18049.18049.2 1.64E-05 26-Dec R.GWEEGVAQMSVGQR.A "sp|P62942|FKB1A_HUMAN,tr|Q1JUQ5|Q1JUQ5_HUMAN,tr|F6T7Q3|F6T7Q3_HUMAN" 3 1532.7042 0.08 33212 18049 2 1532.704987 767.3594 Peptidyl-prolyl cis-trans isomerase FKBP1A OS=Homo sapiens OX=9606 GN=FKBP1A PE=1 SV=2 4.53 3101.3 - 500182 - - - 0.5291 - 2.055 0.545 - 470.1 1 2 0 0.0008 14 0 0 0 3.80E+06 5.03E+07 - - - 4.8736 0.9997 221125_WJC_METTL3_EV_vs_WT_F03.18054.18054.2 6.23E-05 20-Dec K.EIQGFLDC[160.03]AAR.A "sp|Q96BP2|CHCH1_HUMAN,tr|A6NJX6|A6NJX6_HUMAN" 2 1278.6027 0.82 33215 18054 2 1278.600331 640.3086 Coiled-coil-helix-coiled-coil-helix domain-containing protein 1 OS=Homo sapiens OX=9606 GN=CHCHD1 PE=1 SV=1 4.37 3101.8 - 3.76E+06 - - - -1.8301 - 2.111 0.469 - 684.8 1 2 0 -0.0023 11 0 0 0 7.45E+07 9.14E+07 - - - 4.5255 1 221125_WJC_METTL3_EV_vs_WT_F03.18056.18056.3 3.41E-14 26/64 K.LPYDVTPEQALAHEEVK[136.11].T "sp|P46940|IQGA1_HUMAN,tr|H0YLE8|H0YLE8_HUMAN,tr|A0A0J9YXZ5|A0A0J9YXZ5_HUMAN" 3 1945.9877 0.96 33217 18056 3 1945.983958 649.6698 Ras GTPase-activating-like protein IQGAP1 OS=Homo sapiens OX=9606 GN=IQGAP1 PE=1 SV=1 4.4 3102 - 1.57E+06 - - - -1.9013 - 4.406 0.599 - 1196.9 1 2 0 -0.0037 17 0 0 0 3.21E+07 3.36E+07 - - - 8.9637 0.9997 221125_WJC_METTL3_EV_vs_WT_F03.18058.18058.3 0.000656 14/52 R.DLPGALDEKELIEK.M sp|Q96BM9|ARL8A_HUMAN 1 1568.8298 0.94 33219 18058 3 1568.82788 523.9505 ADP-ribosylation factor-like protein 8A OS=Homo sapiens OX=9606 GN=ARL8A PE=1 SV=1 4.18 3102.2 - 1.42E+06 - - - -1.1945 - 2.829 0.396 - 139.9 1 2 1 -0.0019 14 0 0 0 1.97E+07 2.09E+07 - - - 5.7181 0.9999 221125_WJC_METTL3_EV_vs_WT_F03.18059.18059.3 0.000195 13/48 K.KGLTPSQIGVILR.D "sp|P62277|RS13_HUMAN,tr|J3KMX5|J3KMX5_HUMAN" 2 1380.8453 0.98 33220 18059 3 1380.842375 461.289 40S ribosomal protein S13 OS=Homo sapiens OX=9606 GN=RPS13 PE=1 SV=2 11 3102.3 - 1.24E+06 - - - -2.1074 - 2.607 0.427 - 212.4 1 2 0 -0.0029 13 0 0 0 2.35E+08 2.40E+08 - - - 5.8978 0.9998 221125_WJC_METTL3_EV_vs_WT_F03.18060.18060.2 4.85E-07 20-Dec R.SEATFQFTVER.F "sp|Q93009|UBP7_HUMAN,tr|H3BRA2|H3BRA2_HUMAN,tr|A0A669KBL1|A0A669KBL1_HUMAN,tr|H3BUV0|H3BUV0_HUMAN,tr|F5H2X1|F5H2X1_HUMAN,tr|H3BMF6|H3BMF6_HUMAN,tr|H3BQD1|H3BQD1_HUMAN,tr|H3BTM1|H3BTM1_HUMAN" 8 1313.6252 1.03 33221 18060 2 1313.628071 657.8199 Ubiquitin carboxyl-terminal hydrolase 7 OS=Homo sapiens OX=9606 GN=USP7 PE=1 SV=2 4.53 3102.5 - 1.12E+06 - - - 2.2 - 2.584 0.535 - 692.6 1 2 0 0.0029 11 0 0 0 1.94E+07 1.88E+07 - - - 5.5598 0.9999 221125_WJC_METTL3_EV_vs_WT_F03.18063.18063.2 1.03E-06 28-Oct R.LLDPEDVDVPQPDEK.S "sp|Q15149|PLEC_HUMAN,tr|E9PMV1|E9PMV1_HUMAN,tr|H0YDN1|H0YDN1_HUMAN" 3 1707.8203 2.92 33224 18063 2 1707.820015 854.9174 Plectin OS=Homo sapiens OX=9606 GN=PLEC PE=1 SV=3 3.66 3102.9 - 821184 - - - -0.1733 - 2.188 0.614 - 220.2 1 2 0 -0.0003 15 0 0 0 2.68E+07 9.19E+06 - - - 5.5009 1 221125_WJC_METTL3_EV_vs_WT_F03.18066.18066.2 1.57E-11 18/34 K.PSTASAVPELATDPELEK[136.11].K "sp|Q86U44|MTA70_HUMAN,tr|B4E349|B4E349_HUMAN,tr|F5H6D8|F5H6D8_HUMAN,tr|H0YFV6|H0YFV6_HUMAN,tr|B4DTN4|B4DTN4_HUMAN" 5 1861.94 0.03 33225 18066 2 1861.937318 931.9773 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 4 3103.2 - 4.44E+06 - - - -1.4614 - 3.673 0.643 - 599.1 1 1 0 -0.0027 18 0 0 0 2.36E+08 7.82E+09 - - - 6.9879 1 221125_WJC_METTL3_EV_vs_WT_F03.18067.18067.3 1.16E-05 15/48 K.K[136.11]GLTPSQIGVILR[166.11].D "sp|P62277|RS13_HUMAN,tr|J3KMX5|J3KMX5_HUMAN" 2 1398.8678 0.98 33226 18067 3 1398.867356 467.2965 40S ribosomal protein S13 OS=Homo sapiens OX=9606 GN=RPS13 PE=1 SV=2 11 3103.3 - 2.16E+06 - - - -0.2852 - 2.841 0.417 - 331.5 1 2 0 -0.0004 13 0 0 0 2.35E+08 2.40E+08 - - - 6.02 1 221125_WJC_METTL3_EV_vs_WT_F03.18069.18069.2 3.84E-07 17/22 A.PLNVELDPEIQK.V "sp|Q86Y46|K2C73_HUMAN,sp|Q7RTS7|K2C74_HUMAN,sp|Q3SY84|K2C71_HUMAN,sp|P04264|K2C1_HUMAN,tr|F8W1S1|F8W1S1_HUMAN" 5 1393.7453 33.43 33228 18069 2 1393.743719 697.8799 "Keratin, type II cytoskeletal 73 OS=Homo sapiens OX=9606 GN=KRT73 PE=1 SV=1" 4.14 3103.5 - 2.06E+06 - - - -1.1315 - 3.032 0.604 - 1149.2 1 1 0 -0.0016 12 0 0 0 2.83E+07 8.46E+05 - - - 6.4202 0.9998 221125_WJC_METTL3_EV_vs_WT_F03.18070.18070.2 0.00146 18-Oct R.FLDELEDEAK.A sp|Q9Y2R0|COA3_HUMAN 1 1207.5608 1.6 33229 18070 2 1207.560597 604.7877 "Cytochrome c oxidase assembly factor 3 homolog, mitochondrial OS=Homo sapiens OX=9606 GN=COA3 PE=1 SV=1" 3.83 3103.6 - 2.05E+06 - - - -0.2087 - 1.983 0.462 - 229.2 1 2 0 -0.0003 10 0 0 0 2.46E+07 1.54E+07 - - - 4.3642 0.9966 221125_WJC_METTL3_EV_vs_WT_F03.18073.18073.2 5.00E-08 16/28 K.AVVQVFEGTSGIDAK[136.11].K "sp|P21281|VATB2_HUMAN,tr|H0YC04|H0YC04_HUMAN" 2 1527.8024 3.77 33232 18073 2 1527.79352 764.9085 "V-type proton ATPase subunit B, brain isoform OS=Homo sapiens OX=9606 GN=ATP6V1B2 PE=1 SV=3" 4.37 3103.9 - 1.44E+06 - - - -5.8273 - 2.837 0.494 - 786.2 1 2 0 -0.0089 15 0 0 0 6.27E+07 1.67E+07 - - - 5.2505 0.8822 221125_WJC_METTL3_EV_vs_WT_F03.18076.18076.2 0.0346 Jul-32 R.LFVNGEVVSAQGYEYDN.L "sp|Q9NXB0|MKS1_HUMAN,tr|A0A7I2V4C1|A0A7I2V4C1_HUMAN,tr|J3QQP4|J3QQP4_HUMAN,tr|J3KRR3|J3KRR3_HUMAN,tr|H0Y2S2|H0Y2S2_HUMAN,tr|A0A7I2V2M0|A0A7I2V2M0_HUMAN,tr|J3KSF4|J3KSF4_HUMAN,tr|A0A0S2Z5Z2|A0A0S2Z5Z2_HUMAN,tr|J3KSC6|J3KSC6_HUMAN" 9 1902.8636 - 33235 18076 2 1902.861555 952.4391 Meckel syndrome type 1 protein OS=Homo sapiens OX=9606 GN=MKS1 PE=1 SV=2 3.57 3104.3 - 938888 - - - -1.0605 - 1.361 0.281 - 75.8 1 1 0 -0.002 17 0 0 0 - - - - - 1.8736 0.9995 221125_WJC_METTL3_EV_vs_WT_F03.18080.18080.2 0.0222 22-Nov K.VEESSWLIEDGK[136.11].V sp|Q9Y266|NUDC_HUMAN 1 1398.6758 1.74 33239 18080 2 1398.678086 700.3452 Nuclear migration protein nudC OS=Homo sapiens OX=9606 GN=NUDC PE=1 SV=1 4 3104.8 - 484424 - - - 1.6158 - 2.02 0.366 - 247.8 1 2 0 0.0023 12 0 0 0 1.77E+08 1.02E+08 - - - 3.5935 0.9999 221125_WJC_METTL3_EV_vs_WT_F03.18083.18083.2 2.12E-06 13/24 K.LFIGGLNTETNEK.A "sp|Q96E39|RMXL1_HUMAN,sp|P38159|RBMX_HUMAN,tr|A0A1B0GUK8|A0A1B0GUK8_HUMAN,tr|H3BT71|H3BT71_HUMAN,tr|H0Y6E7|H0Y6E7_HUMAN,tr|H3BR27|H3BR27_HUMAN,tr|H3BNC1|H3BNC1_HUMAN" 7 1434.7355 1.5 33241 18083 2 1434.734714 718.375 "RNA binding motif protein, X-linked-like-1 OS=Homo sapiens OX=9606 GN=RBMXL1 PE=1 SV=1" 4.53 3105.2 - 1.17E+08 - - - -0.5193 - 2.423 0.587 - 388.8 1 2 0 -0.0007 13 0 0 0 1.67E+09 1.11E+09 - - - 5.6477 0.9998 221125_WJC_METTL3_EV_vs_WT_F03.18084.18084.3 0.000142 13/44 R.YLYTLVITDKEK.A "sp|P63173|RL38_HUMAN,tr|J3KT73|J3KT73_HUMAN,tr|J3QL01|J3QL01_HUMAN" 3 1484.8126 1.09 33242 18084 3 1484.811775 495.9448 60S ribosomal protein L38 OS=Homo sapiens OX=9606 GN=RPL38 PE=1 SV=2 6.07 3105.2 - 1.83E+07 - - - -0.5873 - 2.31 0.479 - 155.9 1 2 1 -0.0009 12 0 0 0 6.56E+09 5.99E+09 - - - 6.2009 1 221125_WJC_METTL3_EV_vs_WT_F03.18085.18085.3 4.85E-05 Sep-68 K.LLLNVTPTVRPDADQMTK.L "sp|Q6P3W7|SCYL2_HUMAN,tr|F8VSC5|F8VSC5_HUMAN,tr|A0A0U1RQQ9|A0A0U1RQQ9_HUMAN" 3 2011.0772 2.25 33243 18085 3 2011.075825 671.3663 SCY1-like protein 2 OS=Homo sapiens OX=9606 GN=SCYL2 PE=1 SV=1 5.96 3105.2 - 6.39E+06 - - - -0.6897 - 2.304 0.5 - 67.2 1 2 0 -0.0014 18 0 0 0 1.11E+08 4.92E+07 - - - 6.1925 0.9996 221125_WJC_METTL3_EV_vs_WT_F03.18086.18086.3 0.00278 15/52 R.VDEIIWVK[136.11]TNQLQR[166.11].L sp|Q86U44|MTA70_HUMAN 1 1758.9747 0.03 33244 18086 3 1758.97033 587.3322 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 6.04 3105.3 - 3.83E+06 - - - -2.5066 - 3.032 0.447 - 479.3 1 2 1 -0.0044 14 0 0 0 9.88E+05 3.73E+07 - - - 6.4702 1 221125_WJC_METTL3_EV_vs_WT_F03.18087.18087.3 1.25E-06 Dec-48 R.AGHLC[160.03]TVQFLISK.G "sp|Q8IWZ3|ANKH1_HUMAN,tr|E9PDP5|E9PDP5_HUMAN,tr|H3BLS9|H3BLS9_HUMAN,tr|H7C2F5|H7C2F5_HUMAN" 4 1472.781 0.68 33245 18087 3 1472.779374 491.9343 Ankyrin repeat and KH domain-containing protein 1 OS=Homo sapiens OX=9606 GN=ANKHD1 PE=1 SV=1 8.27 3105.4 - 3.11E+06 - - - -1.0837 - 2.497 0.473 - 282.1 1 2 0 -0.0016 13 0 0 0 5.57E+07 8.22E+07 - - - 6.2941 1 221125_WJC_METTL3_EV_vs_WT_F03.18088.18088.3 2.18E-09 23/64 K.LPYDVTPEQALAHEEVK.T "sp|P46940|IQGA1_HUMAN,tr|H0YLE8|H0YLE8_HUMAN,tr|A0A0J9YXZ5|A0A0J9YXZ5_HUMAN" 3 1937.9735 0.89 33246 18088 3 1937.969989 646.9984 Ras GTPase-activating-like protein IQGAP1 OS=Homo sapiens OX=9606 GN=IQGAP1 PE=1 SV=1 4.4 3105.4 - 2.57E+06 - - - -1.79 - 3.966 0.636 - 636.1 1 2 0 -0.0035 17 0 0 0 3.21E+07 3.61E+07 - - - 9.1104 0.9999 221125_WJC_METTL3_EV_vs_WT_F03.18092.18092.3 6.49E-07 14/48 K.LGFDK[136.11]ENVYDELR[166.11].Q sp|O60264|SMCA5_HUMAN 1 1614.8009 1.46 33250 18092 3 1614.801013 539.2742 SWI\SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A member 5 OS=Homo sapiens OX=9606 GN=SMARCA5 PE=1 SV=1 4.32 3105.9 - 1.65E+06 - - - 0.0966 - 2.877 0.568 - 271.6 1 2 1 0.0002 13 0 0 0 1.33E+07 9.07E+06 - - - 7.7377 0.9984 221125_WJC_METTL3_EV_vs_WT_F03.18094.18094.3 0.000445 Nov-40 R.KLAVNMVPFPR.L "sp|P04350|TBB4A_HUMAN,sp|Q9BVA1|TBB2B_HUMAN,sp|A6NNZ2|TBB8B_HUMAN,sp|P07437|TBB5_HUMAN,sp|Q13509|TBB3_HUMAN,sp|Q13885|TBB2A_HUMAN,sp|P68371|TBB4B_HUMAN,sp|Q9BUF5|TBB6_HUMAN,sp|Q3ZCM7|TBB8_HUMAN,sp|Q9H4B7|TBB1_HUMAN,tr|A0A0B4J269|A0A0B4J269_HUMAN,tr|Q5ST81|Q5ST81_HUMAN,tr|Q5JP53|Q5JP53_HUMAN,tr|K7ESM5|K7ESM5_HUMAN,tr|A0A075B736|A0A075B736_HUMAN,tr|Q5SQY0|Q5SQY0_HUMAN" 16 1270.722 0.69 33252 18094 3 1270.718776 424.5813 Tubulin beta-4A chain OS=Homo sapiens OX=9606 GN=TUBB4A PE=1 SV=2 11 3106 - 1.39E+06 - - - -2.5356 - 1.874 0.303 - 134.2 1 2 0 -0.0032 11 0 0 0 6.36E+07 9.19E+07 - - - 3.7015 1 221125_WJC_METTL3_EV_vs_WT_F03.18096.18096.2 0.000122 14/20 R.FTDEEVDELYR.E "sp|O14950|ML12B_HUMAN,sp|P19105|ML12A_HUMAN,tr|J3QRS3|J3QRS3_HUMAN" 3 1414.6252 1.63 33254 18096 2 1414.626917 708.3199 Myosin regulatory light chain 12B OS=Homo sapiens OX=9606 GN=MYL12B PE=1 SV=2 3.83 3106.3 - 1.26E+06 - - - 1.1855 - 2.763 0.562 - 686.9 1 2 0 0.0017 11 0 0 0 3.48E+07 2.14E+07 - - - 5.9408 0.9989 221125_WJC_METTL3_EV_vs_WT_F03.18097.18097.3 0.00272 Oct-48 K.LFIGGLNTETNEK.A "sp|Q96E39|RMXL1_HUMAN,sp|P38159|RBMX_HUMAN,tr|A0A1B0GUK8|A0A1B0GUK8_HUMAN,tr|H3BT71|H3BT71_HUMAN,tr|H0Y6E7|H0Y6E7_HUMAN,tr|H3BR27|H3BR27_HUMAN,tr|H3BNC1|H3BNC1_HUMAN" 7 1434.7355 1.35 33255 18097 3 1434.731742 479.2524 "RNA binding motif protein, X-linked-like-1 OS=Homo sapiens OX=9606 GN=RBMXL1 PE=1 SV=1" 4.53 3106.4 - 1.13E+06 - - - -2.5907 - 1.703 0.36 - 95.3 1 2 0 -0.0037 13 0 0 0 1.56E+07 1.16E+07 - - - 3.9961 1 221125_WJC_METTL3_EV_vs_WT_F03.18099.18099.2 1.34E-05 14/22 K.NAAQFLLSTNDK.T sp|P63151|2ABA_HUMAN 1 1320.6674 0.51 33256 18099 2 1320.66685 661.341 Serine\threonine-protein phosphatase 2A 55 kDa regulatory subunit B alpha isoform OS=Homo sapiens OX=9606 GN=PPP2R2A PE=1 SV=1 5.84 3106.6 - 5.74E+06 - - - -0.4013 - 2.841 0.549 - 833.3 1 2 0 -0.0005 12 0 0 0 7.61E+07 1.48E+08 - - - 5.8431 1 221125_WJC_METTL3_EV_vs_WT_F03.18101.18101.3 1.76E-07 Dec-48 R.QVQSLTC[160.03]EVDALK[136.11].G "sp|P08670|VIME_HUMAN,tr|B0YJC5|B0YJC5_HUMAN,tr|B0YJC4|B0YJC4_HUMAN" 3 1497.7588 1.8 33257 18101 3 1497.757164 500.2602 Vimentin OS=Homo sapiens OX=9606 GN=VIM PE=1 SV=4 4.37 3106.8 - 6.94E+06 - - - -1.1217 - 2.422 0.561 - 194.3 1 2 0 -0.0017 13 0 0 0 1.13E+08 6.25E+07 - - - 7.1925 0.9999 221125_WJC_METTL3_EV_vs_WT_F03.18102.18102.3 0.000291 13/40 R.K[136.11]LAVNMVPFPR[166.11].L "sp|P04350|TBB4A_HUMAN,sp|Q9BVA1|TBB2B_HUMAN,sp|A6NNZ2|TBB8B_HUMAN,sp|P07437|TBB5_HUMAN,sp|Q13509|TBB3_HUMAN,sp|Q13885|TBB2A_HUMAN,sp|P68371|TBB4B_HUMAN,sp|Q9BUF5|TBB6_HUMAN,sp|Q3ZCM7|TBB8_HUMAN,sp|Q9H4B7|TBB1_HUMAN,tr|A0A0B4J269|A0A0B4J269_HUMAN,tr|Q5ST81|Q5ST81_HUMAN,tr|Q5JP53|Q5JP53_HUMAN,tr|K7ESM5|K7ESM5_HUMAN,tr|A0A075B736|A0A075B736_HUMAN,tr|Q5SQY0|Q5SQY0_HUMAN" 16 1288.7445 0.71 33258 18102 3 1288.7422 430.5888 Tubulin beta-4A chain OS=Homo sapiens OX=9606 GN=TUBB4A PE=1 SV=2 11 3106.8 - 5.38E+06 - - - -1.7599 - 2.21 0.467 - 211.5 1 2 0 -0.0023 11 0 0 0 6.34E+07 8.98E+07 - - - 5.9987 0.9999 221125_WJC_METTL3_EV_vs_WT_F03.18105.18105.2 2.07E-07 22-Dec K.VEESSWLIEDGK.V sp|Q9Y266|NUDC_HUMAN 1 1390.6616 1.6 33261 18105 2 1390.660081 696.3381 Nuclear migration protein nudC OS=Homo sapiens OX=9606 GN=NUDC PE=1 SV=1 4 3107 - 4.46E+06 - - - -1.111 - 2.527 0.564 - 461.7 1 2 0 -0.0015 12 0 0 0 1.82E+08 1.14E+08 - - - 5.6454 1 221125_WJC_METTL3_EV_vs_WT_F03.18106.18106.3 1.59E-06 15/60 K.IFVGGLPYHTTDASLR.K "sp|Q9H0Z9|RBM38_HUMAN,sp|Q9BX46|RBM24_HUMAN,tr|F6VZ39|F6VZ39_HUMAN,tr|E9PSF1|E9PSF1_HUMAN" 4 1745.9101 3.36 33262 18106 3 1745.907753 582.9773 RNA-binding protein 38 OS=Homo sapiens OX=9606 GN=RBM38 PE=1 SV=2 6.74 3107.1 - 2.96E+06 - - - -1.3271 - 2.945 0.47 - 271.5 1 2 0 -0.0023 16 0 0 0 2.35E+07 7.00E+06 - - - 6.5508 1 221125_WJC_METTL3_EV_vs_WT_F03.18107.18107.3 0.000208 18/52 R.GAFFMDEDEEVYKR.D sp|P55081|MFAP1_HUMAN 1 1734.7559 2.37 33263 18107 3 1734.753652 579.2593 Microfibrillar-associated protein 1 OS=Homo sapiens OX=9606 GN=MFAP1 PE=1 SV=2 4.18 3107.2 - 2.23E+06 - - - -1.3172 - 3.202 0.576 - 263.1 1 2 0 -0.0023 14 0 0 0 2.16E+07 9.12E+06 - - - 8.054 1 221125_WJC_METTL3_EV_vs_WT_F03.18108.18108.2 4.73E-10 16/28 R.AVIYNPATQADWTAK[136.11].K "sp|P35580|MYH10_HUMAN,tr|E7ERA5|E7ERA5_HUMAN" 2 1655.8399 1.03 33264 18108 2 1655.836322 828.9272 Myosin-10 OS=Homo sapiens OX=9606 GN=MYH10 PE=1 SV=3 5.88 3107.3 - 2.22E+06 - - - -2.1433 - 3.248 0.62 - 871 1 2 0 -0.0035 15 0 0 0 5.53E+07 5.39E+07 - - - 6.5155 0.8561 221125_WJC_METTL3_EV_vs_WT_F03.18109.18109.3 1.05 Sep-48 K.LFIGGLNTETNEK[136.11].A "sp|Q96E39|RMXL1_HUMAN,sp|P38159|RBMX_HUMAN,tr|A0A1B0GUK8|A0A1B0GUK8_HUMAN,tr|H3BT71|H3BT71_HUMAN,tr|H0Y6E7|H0Y6E7_HUMAN,tr|H3BR27|H3BR27_HUMAN,tr|H3BNC1|H3BNC1_HUMAN" 7 1442.7497 1.57 33265 18109 3 1442.748313 481.9238 "RNA binding motif protein, X-linked-like-1 OS=Homo sapiens OX=9606 GN=RBMXL1 PE=1 SV=1" 4.53 3107.4 - 1.44E+06 - - - -0.9329 - 1.339 0.08 - 72.1 1 2 0 -0.0013 13 0 0 0 1.88E+07 1.20E+07 - - - 0.223 0.9995 221125_WJC_METTL3_EV_vs_WT_F03.18111.18111.3 0.139 Dec-44 R.DIKPDNLLLDAK.G "sp|Q9Y2H1|ST38L_HUMAN,tr|F5H277|F5H277_HUMAN,tr|H0YGN4|H0YGN4_HUMAN" 3 1353.7504 3.81 33267 18111 3 1353.750025 452.2574 Serine\threonine-protein kinase 38-like OS=Homo sapiens OX=9606 GN=STK38L PE=1 SV=3 4.43 3107.7 - 798698 - - - -0.263 - 2.317 0.26 - 235.4 1 2 0 -0.0004 12 0 0 0 1.70E+08 4.45E+07 - - - 3.7678 0.98 221125_WJC_METTL3_EV_vs_WT_F03.18119.18119.2 8.20E-05 20-Oct H.LQLWDTAGQER[166.11].F "sp|P51159|RB27A_HUMAN,sp|Q9H082|RB33B_HUMAN,sp|P20336|RAB3A_HUMAN,sp|Q8IZ41|RASEF_HUMAN,sp|P20337|RAB3B_HUMAN,sp|Q96E17|RAB3C_HUMAN,sp|P61006|RAB8A_HUMAN,sp|P61026|RAB10_HUMAN,sp|Q15286|RAB35_HUMAN,sp|O00194|RB27B_HUMAN,sp|Q14964|RB39A_HUMAN,sp|Q9H0U4|RAB1B_HUMAN,sp|P61018|RAB4B_HUMAN,sp|P59190|RAB15_HUMAN,sp|Q9BZG1|RAB34_HUMAN,sp|Q9NP90|RAB9B_HUMAN,sp|Q9BSW2|EFC4B_HUMAN,sp|P20338|RAB4A_HUMAN,sp|Q15771|RAB30_HUMAN,sp|P62820|RAB1A_HUMAN,sp|Q5JT25|RAB41_HUMAN,sp|Q86YS6|RAB43_HUMAN,sp|Q96DA2|RB39B_HUMAN,sp|P20340|RAB6A_HUMAN,sp|Q96AX2|RAB37_HUMAN,sp|Q7Z6P3|RAB44_HUMAN,sp|Q9NRW1|RAB6B_HUMAN,sp|O95716|RAB3D_HUMAN,sp|Q6IQ22|RAB12_HUMAN,sp|Q92930|RAB8B_HUMAN,sp|Q92928|RAB1C_HUMAN,sp|P61106|RAB14_HUMAN,tr|A8MZI4|A8MZI4_HUMAN,tr|A0A494C0Z5|A0A494C0Z5_HUMAN,tr|H3BVH7|H3BVH7_HUMAN,tr|E9PJQ5|E9PJQ5_HUMAN,tr|H0YMN7|H0YMN7_HUMAN,tr|C9JBG0|C9JBG0_HUMAN,tr|A8MTC6|A8MTC6_HUMAN,tr|B7Z3L0|B7Z3L0_HUMAN,tr|E9PS06|E9PS06_HUMAN,tr|A0A2R8Y7G7|A0A2R8Y7G7_HUMAN,tr|A8MSP2|A8MSP2_HUMAN,tr|E9PNB9|E9PNB9_HUMAN,tr|E9PLM3|E9PLM3_HUMAN,tr|H0YNE9|H0YNE9_HUMAN,tr|E9PI18|E9PI18_HUMAN,tr|G3V196|G3V196_HUMAN,tr|X6RFL8|X6RFL8_HUMAN,tr|Q6PIK3|Q6PIK3_HUMAN,tr|A0A3B3ITT1|A0A3B3ITT1_HUMAN,tr|Q96PJ7|Q96PJ7_HUMAN,tr|C9JB90|C9JB90_HUMAN,tr|J3KR73|J3KR73_HUMAN,tr|A0A2R8YFB8|A0A2R8YFB8_HUMAN,tr|H3BUD9|H3BUD9_HUMAN,tr|J3QLC6|J3QLC6_HUMAN,tr|M0R257|M0R257_HUMAN,tr|J3QSF4|J3QSF4_HUMAN,tr|E7ES60|E7ES60_HUMAN,tr|H0YDK7|H0YDK7_HUMAN,tr|C9JFM7|C9JFM7_HUMAN,tr|H3BS49|H3BS49_HUMAN,tr|M0R0X1|M0R0X1_HUMAN,tr|C9JY26|C9JY26_HUMAN,tr|K7ES41|K7ES41_HUMAN,tr|H3BN55|H3BN55_HUMAN,tr|H7C0Y7|H7C0Y7_HUMAN,tr|C9JU14|C9JU14_HUMAN,tr|E9PRF7|E9PRF7_HUMAN,tr|G3V562|G3V562_HUMAN,tr|F5H157|F5H157_HUMAN,tr|E9PMJ1|E9PMJ1_HUMAN,tr|K7EIF2|K7EIF2_HUMAN" 74 1325.6603 1.17 33273 18119 2 1325.659072 663.8374 Ras-related protein Rab-27A OS=Homo sapiens OX=9606 GN=RAB27A PE=1 SV=3 4.37 3108.7 - 1.16E+07 - - - -0.952 - 2.07 0.353 - 306.7 1 1 0 -0.0013 11 0 0 0 1.82E+08 1.55E+08 - - - 3.6161 0.9939 221125_WJC_METTL3_EV_vs_WT_F03.18120.18120.2 4.65E-05 18-Dec F.SAFGNILSC[160.03]K.V "sp|Q13310|PABP4_HUMAN,sp|Q5JQF8|PAP1M_HUMAN,sp|Q96DU9|PABP5_HUMAN,sp|P11940|PABP1_HUMAN,tr|A0A7I2V5W9|A0A7I2V5W9_HUMAN,tr|A0A7I2YQE4|A0A7I2YQE4_HUMAN,tr|A0A7I2V649|A0A7I2V649_HUMAN,tr|B1ANR0|B1ANR0_HUMAN,tr|A0A7I2V4L7|A0A7I2V4L7_HUMAN,tr|B1ANR1|B1ANR1_HUMAN,tr|H0YAR2|H0YAR2_HUMAN,tr|A0A7I2V598|A0A7I2V598_HUMAN,tr|E5RJB9|E5RJB9_HUMAN,tr|A0A7I2YQ88|A0A7I2YQ88_HUMAN,tr|H0YEQ8|H0YEQ8_HUMAN,tr|H0Y5F5|H0Y5F5_HUMAN,tr|E5RGH3|E5RGH3_HUMAN,tr|A0A7I2YQ90|A0A7I2YQ90_HUMAN,tr|A0A7I2V4N4|A0A7I2V4N4_HUMAN,tr|E7EQV3|E7EQV3_HUMAN" 20 1095.5383 1.37 33274 18120 2 1095.53709 548.7764 Polyadenylate-binding protein 4 OS=Homo sapiens OX=9606 GN=PABPC4 PE=1 SV=1 7.94 3108.8 - 2.80E+06 - - - -1.0862 - 2.138 0.612 - 376 1 1 0 -0.0012 10 0 0 0 5.74E+07 4.18E+07 - - - 5.6819 0.9999 221125_WJC_METTL3_EV_vs_WT_F03.18121.18121.2 2.39E-05 22-Nov R.IDSFSVQSLDSR[166.11].S "sp|P82094|TMF1_HUMAN,tr|F8WF45|F8WF45_HUMAN,tr|A0A2R8Y7M0|A0A2R8Y7M0_HUMAN" 3 1362.6655 1.51 33275 18121 2 1362.66571 682.34 TATA element modulatory factor OS=Homo sapiens OX=9606 GN=TMF1 PE=1 SV=2 4.21 3108.9 - 7.28E+06 - - - 0.1695 - 2.409 0.485 - 514.6 1 2 0 0.0002 12 0 0 0 1.09E+08 7.25E+07 - - - 4.9365 0.9823 221125_WJC_METTL3_EV_vs_WT_F03.18122.18122.2 1.69E-05 26-Dec R.VPTANVSVVDLTC[160.03]R[166.11].L "sp|P04406|G3P_HUMAN,tr|E7EUT5|E7EUT5_HUMAN" 2 1539.7954 1.02 33276 18122 2 1539.804919 770.905 Glyceraldehyde-3-phosphate dehydrogenase OS=Homo sapiens OX=9606 GN=GAPDH PE=1 SV=3 5.8 3108.9 - 4.14E+06 - - - 6.1508 - 2.494 0.254 - 478 1 2 0 0.0095 14 0 0 0 8.36E+09 8.16E+09 - - - 3.2074 0.9999 221125_WJC_METTL3_EV_vs_WT_F03.18124.18124.2 0.000999 20-Dec R.K[136.11]LAVNMVPFPR[166.11].L "sp|P04350|TBB4A_HUMAN,sp|Q9BVA1|TBB2B_HUMAN,sp|A6NNZ2|TBB8B_HUMAN,sp|P07437|TBB5_HUMAN,sp|Q13509|TBB3_HUMAN,sp|Q13885|TBB2A_HUMAN,sp|P68371|TBB4B_HUMAN,sp|Q9BUF5|TBB6_HUMAN,sp|Q3ZCM7|TBB8_HUMAN,sp|Q9H4B7|TBB1_HUMAN,tr|A0A0B4J269|A0A0B4J269_HUMAN,tr|Q5ST81|Q5ST81_HUMAN,tr|Q5JP53|Q5JP53_HUMAN,tr|K7ESM5|K7ESM5_HUMAN,tr|A0A075B736|A0A075B736_HUMAN,tr|Q5SQY0|Q5SQY0_HUMAN" 16 1288.7445 0.66 33278 18124 2 1288.743298 645.3795 Tubulin beta-4A chain OS=Homo sapiens OX=9606 GN=TUBB4A PE=1 SV=2 11 3109 - 2.71E+06 - - - -0.9079 - 2.535 0.512 - 493.3 1 2 0 -0.0012 11 0 0 0 1.94E+07 2.94E+07 - - - 5.3387 0.9997 221125_WJC_METTL3_EV_vs_WT_F03.18125.18125.2 1.77E-05 14/20 R.FTDEEVDELYR[166.11].E "sp|O14950|ML12B_HUMAN,sp|P19105|ML12A_HUMAN,tr|J3QRS3|J3QRS3_HUMAN" 3 1424.6335 1.95 33279 18125 2 1424.63001 713.324 Myosin regulatory light chain 12B OS=Homo sapiens OX=9606 GN=MYL12B PE=1 SV=2 3.83 3109.2 - 2.27E+06 - - - -2.4568 - 2.687 0.525 - 654 1 2 0 -0.0035 11 0 0 0 4.23E+07 2.17E+07 - - - 5.5915 0.9997 221125_WJC_METTL3_EV_vs_WT_F03.18127.18127.2 0.000175 20-Dec R.IQLQIQETLQR.Q "sp|O75694|NU155_HUMAN,tr|E9PF10|E9PF10_HUMAN" 2 1368.7725 2.55 33281 18127 2 1368.770494 685.3935 Nuclear pore complex protein Nup155 OS=Homo sapiens OX=9606 GN=NUP155 PE=1 SV=1 6 3109.4 - 1.96E+06 - - - -1.4758 - 2.689 0.347 - 516.4 1 2 0 -0.002 11 0 0 0 2.99E+07 1.17E+07 - - - 4.2792 0.9998 221125_WJC_METTL3_EV_vs_WT_F03.18129.18129.3 3.49E-06 14/40 K.LRLEVNLQAMK.A sp|P35579|MYH9_HUMAN 1 1313.7489 1.02 33283 18129 3 1313.746935 438.9236 Myosin-9 OS=Homo sapiens OX=9606 GN=MYH9 PE=1 SV=4 8.75 3109.6 - 1.68E+06 - - - -1.5269 - 2.989 0.44 - 416.8 1 2 1 -0.002 11 0 0 0 1.51E+07 1.48E+07 - - - 6.5555 0.9998 221125_WJC_METTL3_EV_vs_WT_F03.18130.18130.2 1.25E-07 26-Nov R.ITPSYVAFTPEGER[166.11].L "sp|P11021|BIP_HUMAN,tr|A0A7P0TB36|A0A7P0TB36_HUMAN,tr|A0A7P0TAI0|A0A7P0TAI0_HUMAN" 3 1575.7808 0.61 33284 18130 2 1575.777364 788.8977 Endoplasmic reticulum chaperone BiP OS=Homo sapiens OX=9606 GN=HSPA5 PE=1 SV=2 4.53 3109.7 - 908367 - - - -2.2078 - 2.377 0.58 - 415.1 1 2 0 -0.0035 14 0 0 0 1.45E+08 2.38E+08 - - - 5.4966 0.959 221125_WJC_METTL3_EV_vs_WT_F03.18135.18135.3 0.0622 13/36 A.ISFHLPINSR[166.11].K "sp|P49755|TMEDA_HUMAN,tr|G3V2K7|G3V2K7_HUMAN" 2 1192.6592 1.31 33287 18135 3 1192.656734 398.5603 Transmembrane emp24 domain-containing protein 10 OS=Homo sapiens OX=9606 GN=TMED10 PE=1 SV=2 9.76 3110.2 - 2.60E+06 - - - -2.0777 - 2 0.354 - 184.3 1 1 0 -0.0025 10 0 0 0 9.70E+07 7.39E+07 - - - 4.5104 0.9999 221125_WJC_METTL3_EV_vs_WT_F03.18136.18136.3 3.82E-05 13/52 R.VPTANVSVVDLTC[160.03]R.L "sp|P04406|G3P_HUMAN,tr|E7EUT5|E7EUT5_HUMAN" 2 1529.7872 1.04 33288 18136 3 1529.784733 510.9363 Glyceraldehyde-3-phosphate dehydrogenase OS=Homo sapiens OX=9606 GN=GAPDH PE=1 SV=3 5.8 3110.3 - 2.43E+06 - - - -1.5983 - 2.512 0.453 - 201.8 1 2 0 -0.0024 14 0 0 0 1.95E+09 1.86E+09 - - - 6.0376 0.9999 221125_WJC_METTL3_EV_vs_WT_F03.18137.18137.3 0.000108 15/44 R.DIK[136.11]PDNLLLDAK[136.11].G "sp|Q9Y2H1|ST38L_HUMAN,tr|F5H277|F5H277_HUMAN,tr|H0YGN4|H0YGN4_HUMAN" 3 1369.7788 3.83 33289 18137 3 1369.777913 457.6002 Serine\threonine-protein kinase 38-like OS=Homo sapiens OX=9606 GN=STK38L PE=1 SV=3 4.43 3110.4 - 2.35E+06 - - - -0.6337 - 2.396 0.369 - 335.8 1 2 0 -0.0009 12 0 0 0 1.70E+08 4.43E+07 - - - 5.0758 0.9989 221125_WJC_METTL3_EV_vs_WT_F03.18138.18138.3 0.000974 13/40 K.LR[166.11]LEVNLQAMK[136.11].A sp|P35579|MYH9_HUMAN 1 1331.7714 1.02 33290 18138 3 1331.769824 444.9311 Myosin-9 OS=Homo sapiens OX=9606 GN=MYH9 PE=1 SV=4 8.75 3110.5 - 1.89E+06 - - - -1.1916 - 2.062 0.346 - 276.1 1 2 1 -0.0016 11 0 0 0 1.51E+07 1.48E+07 - - - 4.453 0.9798 221125_WJC_METTL3_EV_vs_WT_F03.18140.18140.2 5.16E-07 26-Oct R.ITPSYVAFTPEGER.L "sp|P11021|BIP_HUMAN,tr|A0A7P0TB36|A0A7P0TB36_HUMAN,tr|A0A7P0TAI0|A0A7P0TAI0_HUMAN" 3 1565.7726 0.61 33292 18140 2 1565.765489 783.8936 Endoplasmic reticulum chaperone BiP OS=Homo sapiens OX=9606 GN=HSPA5 PE=1 SV=2 4.53 3110.8 - 1.25E+06 - - - -4.5243 - 2.291 0.122 - 296.5 1 2 0 -0.0071 14 0 0 0 1.45E+08 2.38E+08 - - - 2.0202 0.9995 221125_WJC_METTL3_EV_vs_WT_F03.18142.18142.2 5.50E-07 22-Dec K.ITQDTLYWNNYK.T "sp|Q8TED0|UTP15_HUMAN,tr|D6RF65|D6RF65_HUMAN" 2 1557.7464 0.39 33294 18142 2 1557.741361 779.8805 U3 small nucleolar RNA-associated protein 15 homolog OS=Homo sapiens OX=9606 GN=UTP15 PE=1 SV=3 5.83 3111 - 783735 - - - -3.2078 - 2.586 0.532 - 657.6 1 2 0 -0.005 12 0 0 0 1.61E+07 4.17E+07 - - - 5.4687 0.9999 221125_WJC_METTL3_EV_vs_WT_F03.18146.18146.2 1.09E-06 28-Dec R.AVIYNPATQADWTAK.K "sp|P35580|MYH10_HUMAN,tr|E7ERA5|E7ERA5_HUMAN" 2 1647.8257 0.29 33297 18146 2 1647.824075 824.9201 Myosin-10 OS=Homo sapiens OX=9606 GN=MYH10 PE=1 SV=3 5.88 3111.6 - 2.86E+06 - - - -0.9685 - 2.757 0.56 - 414.9 1 2 0 -0.0016 15 0 0 0 6.78E+07 2.37E+08 - - - 5.67 0.9902 221125_WJC_METTL3_EV_vs_WT_F03.18148.18148.2 0.000257 18-Nov F.SAFGNILSC[160.03]K[136.11].V "sp|Q13310|PABP4_HUMAN,sp|Q5JQF8|PAP1M_HUMAN,sp|Q96DU9|PABP5_HUMAN,sp|P11940|PABP1_HUMAN,tr|A0A7I2V5W9|A0A7I2V5W9_HUMAN,tr|A0A7I2YQE4|A0A7I2YQE4_HUMAN,tr|A0A7I2V649|A0A7I2V649_HUMAN,tr|B1ANR0|B1ANR0_HUMAN,tr|A0A7I2V4L7|A0A7I2V4L7_HUMAN,tr|B1ANR1|B1ANR1_HUMAN,tr|H0YAR2|H0YAR2_HUMAN,tr|A0A7I2V598|A0A7I2V598_HUMAN,tr|E5RJB9|E5RJB9_HUMAN,tr|A0A7I2YQ88|A0A7I2YQ88_HUMAN,tr|H0YEQ8|H0YEQ8_HUMAN,tr|H0Y5F5|H0Y5F5_HUMAN,tr|E5RGH3|E5RGH3_HUMAN,tr|A0A7I2YQ90|A0A7I2YQ90_HUMAN,tr|A0A7I2V4N4|A0A7I2V4N4_HUMAN,tr|E7EQV3|E7EQV3_HUMAN" 20 1103.5525 1.4 33298 18148 2 1103.552369 552.7835 Polyadenylate-binding protein 4 OS=Homo sapiens OX=9606 GN=PABPC4 PE=1 SV=1 7.94 3111.8 - 3.81E+06 - - - -0.1006 - 1.894 0.476 - 365.8 1 1 0 -0.0001 10 0 0 0 5.74E+07 4.12E+07 - - - 4.3395 0.9963 221125_WJC_METTL3_EV_vs_WT_F03.18149.18149.2 0.000237 15/22 R.LLRDYQELMNVK.L "sp|Q01546|K22O_HUMAN,sp|P12035|K2C3_HUMAN,sp|P35908|K22E_HUMAN,sp|Q5XKE5|K2C79_HUMAN,tr|H0YID6|H0YID6_HUMAN" 5 1520.8021 68.31 33299 18149 2 1520.799501 761.4083 "Keratin, type II cytoskeletal 2 oral OS=Homo sapiens OX=9606 GN=KRT76 PE=1 SV=2" 6.07 3111.9 - 2.36E+06 - - - -1.7083 - 2.486 0.372 - 806.5 1 2 1 -0.0026 12 0 0 0 3.55E+07 5.19E+05 - - - 4.1839 0.9999 221125_WJC_METTL3_EV_vs_WT_F03.18150.18150.3 8.92E-07 17/60 R.VPATTLYAHFEQANIK.T sp|Q7Z3B4|NUP54_HUMAN 1 1801.9363 1.1 33300 18150 3 1801.932656 601.6527 Nucleoporin p54 OS=Homo sapiens OX=9606 GN=NUP54 PE=1 SV=2 6.72 3111.9 - 2.87E+06 - - - -2.0139 - 2.909 0.452 - 445.2 1 2 0 -0.0036 16 0 0 0 3.52E+07 3.22E+07 - - - 6.3182 0.9391 221125_WJC_METTL3_EV_vs_WT_F03.18151.18151.3 0.000466 16/64 R.LIEGLSHEVIVSAAC[160.03]GR.N sp|Q9P258|RCC2_HUMAN 1 1809.9407 2.83 33301 18151 3 1809.945604 604.3208 Protein RCC2 OS=Homo sapiens OX=9606 GN=RCC2 PE=1 SV=2 5.4 3112 - 2.75E+06 - - - 2.6995 - 2.807 0.021 - 333.3 1 2 0 0.0049 17 0 0 0 3.12E+07 1.10E+07 - - - 1.3802 0.9993 221125_WJC_METTL3_EV_vs_WT_F03.18154.18154.3 0.46 14/68 R.LALAAGPALRPDMSYAER.L sp|P54259|ATN1_HUMAN 1 1900.9829 3.59 33304 18154 3 1900.984676 634.6682 Atrophin-1 OS=Homo sapiens OX=9606 GN=ATN1 PE=1 SV=3 6.07 3112.3 - 1.73E+06 - - - 0.9253 - 2.495 0.248 - 274.3 1 2 0 0.0018 18 0 0 0 1.82E+07 5.07E+06 - - - 3.5811 0.9509 221125_WJC_METTL3_EV_vs_WT_F03.18155.18155.3 0.785 Oct-36 M.VKLFIGNLPR.E "sp|Q9BWF3|RBM4_HUMAN,sp|Q9BQ04|RBM4B_HUMAN,tr|E9PM61|E9PM61_HUMAN,tr|D6R9K7|D6R9K7_HUMAN,tr|J3QRR5|J3QRR5_HUMAN,tr|E9PB51|E9PB51_HUMAN,tr|U3KQD5|U3KQD5_HUMAN,tr|E9PLB0|E9PLB0_HUMAN" 8 1155.7128 1.36 33305 18155 3 1155.712868 386.2449 RNA-binding protein 4 OS=Homo sapiens OX=9606 GN=RBM4 PE=1 SV=1 11 3112.4 - 1.44E+06 - - - 0.0467 - 1.715 0.146 - 82.8 1 2 1 0.0001 10 0 0 0 7.40E+07 5.45E+07 - - - 1.7431 0.9773 221125_WJC_METTL3_EV_vs_WT_F03.18156.18156.2 8.95E-08 15/28 R.NGYELSPTAAANFTR.R sp|P49721|PSB2_HUMAN 1 1610.7689 0.51 33306 18156 2 1610.7607 806.3917 Proteasome subunit beta type-2 OS=Homo sapiens OX=9606 GN=PSMB2 PE=1 SV=1 6 3112.5 - 1.17E+06 - - - -5.0814 - 2.397 0.145 - 686.6 1 2 0 -0.0082 15 0 0 0 1.19E+07 2.33E+07 - - - 2.2587 0.9977 221125_WJC_METTL3_EV_vs_WT_F03.18157.18157.2 0.00706 22-Nov K.AIENC[160.03]EYAFNLK.K "sp|Q15796|SMAD2_HUMAN,tr|K7EJX0|K7EJX0_HUMAN,tr|B7Z5N5|B7Z5N5_HUMAN" 3 1470.6813 1.91 33307 18157 2 1470.685467 736.3479 Mothers against decapentaplegic homolog 2 OS=Homo sapiens OX=9606 GN=SMAD2 PE=1 SV=1 4.53 3112.6 - 951588 - - - 2.8225 - 1.925 0.288 - 352.7 1 2 0 0.0042 12 0 0 0 1.14E+07 5.96E+06 - - - 2.8901 0.9998 221125_WJC_METTL3_EV_vs_WT_F03.18158.18158.3 0.00079 Oct-36 R.DYAFVHFTSR.E "sp|A0AV96|RBM47_HUMAN,tr|B7Z8Z7|B7Z8Z7_HUMAN,tr|D6R9D6|D6R9D6_HUMAN" 3 1241.5829 0.98 33308 18158 3 1241.581805 414.8683 RNA-binding protein 47 OS=Homo sapiens OX=9606 GN=RBM47 PE=1 SV=2 6.74 3112.8 - 884335 - - - -0.8997 - 1.772 0.376 - 165.1 1 2 0 -0.0011 10 0 0 0 7.36E+06 7.54E+06 - - - 4.4025 0.8569 221125_WJC_METTL3_EV_vs_WT_F03.18161.18161.3 0.0402 Jul-36 K.MDANVLMHLR[166.11].S sp|Q7Z2T5|TRM1L_HUMAN 1 1208.6034 0.9 33311 18161 3 1209.60343 403.8751 TRMT1-like protein OS=Homo sapiens OX=9606 GN=TRMT1L PE=1 SV=2 6.5 3113.2 - 306043 - - - 827.465 - 1.641 0.283 - 58.6 1 2 0 1.0001 10 0 0 0 2.31E+06 2.58E+06 - - - 2.8647 0.7828 221125_WJC_METTL3_EV_vs_WT_F03.18164.18164.2 2.47E-05 24-Oct K.TAFQEALDAAGDK[136.11].L sp|P10599|THIO_HUMAN 1 1343.6449 0.77 33312 18164 2 1343.636633 672.8297 Thioredoxin OS=Homo sapiens OX=9606 GN=TXN PE=1 SV=3 4.03 3113.6 - 8.40E+06 - - - -6.1229 - 1.837 0.061 - 125.2 2 2 0 -0.0082 13 0 0 0 3.79E+08 4.95E+08 - - - 0.9153 0.9956 221125_WJC_METTL3_EV_vs_WT_F03.18165.18165.3 0.000106 14/36 A.ISFHLPINSR.K "sp|P49755|TMEDA_HUMAN,tr|G3V2K7|G3V2K7_HUMAN" 2 1182.6509 1.32 33313 18165 3 1182.64952 395.2243 Transmembrane emp24 domain-containing protein 10 OS=Homo sapiens OX=9606 GN=TMED10 PE=1 SV=2 9.76 3113.6 - 6.05E+06 - - - -1.2024 - 2.284 0.472 - 222.2 1 1 0 -0.0014 10 0 0 0 9.74E+07 7.41E+07 - - - 6.214 0.9999 221125_WJC_METTL3_EV_vs_WT_F03.18166.18166.2 8.09E-06 24-Dec R.QVQSLTC[160.03]EVDALK[136.11].G "sp|P08670|VIME_HUMAN,tr|B0YJC5|B0YJC5_HUMAN,tr|B0YJC4|B0YJC4_HUMAN" 3 1497.7588 1.85 33314 18166 2 1497.757927 749.8867 Vimentin OS=Homo sapiens OX=9606 GN=VIM PE=1 SV=4 4.37 3113.6 - 5.94E+06 - - - -0.6122 - 2.405 0.501 - 499.1 1 2 0 -0.0009 13 0 0 0 1.57E+09 8.46E+08 - - - 4.9934 0.9998 221125_WJC_METTL3_EV_vs_WT_F03.18167.18167.2 0.0182 16-Oct K.DAEAWFNEK.S "sp|P13645|K1C10_HUMAN,sp|Q7Z3Z0|K1C25_HUMAN,sp|Q7Z3Y8|K1C27_HUMAN,sp|Q7Z3Y7|K1C28_HUMAN,tr|A0A1B0GVI3|A0A1B0GVI3_HUMAN" 5 1108.4825 47288.86 33315 18167 2 1108.482363 555.2485 "Keratin, type I cytoskeletal 10 OS=Homo sapiens OX=9606 GN=KRT10 PE=1 SV=6" 4.14 3113.7 - 4.06E+06 - - - -0.1588 - 2.038 0.436 - 416.3 1 2 0 -0.0002 9 0 0 0 9.71E+09 2.05E+05 - - - 4.321 1 221125_WJC_METTL3_EV_vs_WT_F03.18169.18169.3 2.70E-06 14/52 R.ITPSYVAFTPEGER[166.11].L "sp|P11021|BIP_HUMAN,tr|A0A7P0TB36|A0A7P0TB36_HUMAN,tr|A0A7P0TAI0|A0A7P0TAI0_HUMAN" 3 1575.7808 0.95 33317 18169 3 1575.781371 526.2676 Endoplasmic reticulum chaperone BiP OS=Homo sapiens OX=9606 GN=HSPA5 PE=1 SV=2 4.53 3113.8 - 2.31E+06 - - - 0.3351 - 2.583 0.502 - 119.5 1 2 0 0.0005 14 0 0 0 5.31E+07 5.61E+07 - - - 6.6585 1 221125_WJC_METTL3_EV_vs_WT_F03.18171.18171.3 1.06E-06 15/56 K.VIYHLDEEETPYLVK[136.11].L "sp|O14641|DVL2_HUMAN,tr|I3L2W9|I3L2W9_HUMAN,tr|I3L2N2|I3L2N2_HUMAN" 3 1854.9495 0.56 33319 18171 3 1854.951959 619.3238 Segment polarity protein dishevelled homolog DVL-2 OS=Homo sapiens OX=9606 GN=DVL2 PE=1 SV=1 4.4 3114.1 - 1.19E+06 - - - 1.3353 - 2.982 0.47 - 286.2 1 2 0 0.0025 15 0 0 0 8.64E+06 1.55E+07 - - - 6.6303 0.9999 221125_WJC_METTL3_EV_vs_WT_F03.18172.18172.3 2.38E-05 Nov-36 K.VFDAIMNFK[136.11]K[136.11].E sp|P13639|EF2_HUMAN 1 1227.6657 0.3 33320 18172 3 1227.66276 410.2292 Elongation factor 2 OS=Homo sapiens OX=9606 GN=EEF2 PE=1 SV=4 8.56 3114.2 - 1.15E+06 - - - -2.3671 - 1.911 0.514 - 130.6 1 2 0 -0.0029 10 0 0 0 2.36E+06 7.75E+06 - - - 6.1611 0.9994 221125_WJC_METTL3_EV_vs_WT_F03.18173.18173.3 0.032 17/52 R.VTPTR[166.11]TEIIILATR[166.11].T "sp|P23396|RS3_HUMAN,tr|H0YEU2|H0YEU2_HUMAN,tr|E9PL09|E9PL09_HUMAN,tr|E9PK82|E9PK82_HUMAN,tr|F2Z2S8|F2Z2S8_HUMAN,tr|H0YCJ7|H0YCJ7_HUMAN,tr|E9PQ96|E9PQ96_HUMAN,tr|E9PJH4|E9PJH4_HUMAN,tr|E9PPU1|E9PPU1_HUMAN,tr|H0YF32|H0YF32_HUMAN" 10 1602.9572 0.69 33321 18173 3 1602.958776 535.3263 40S ribosomal protein S3 OS=Homo sapiens OX=9606 GN=RPS3 PE=1 SV=2 9.57 3114.3 - 1.11E+06 - - - 0.9944 - 2.666 0.346 - 296.7 1 2 1 0.0016 14 0 0 0 6.50E+07 9.46E+07 - - - 5.003 0.9782 221125_WJC_METTL3_EV_vs_WT_F03.18175.18175.3 0.237 Nov-52 K.FLQEFYQDDELGK[136.11]K[136.11].Q sp|P33993|MCM7_HUMAN 1 1774.8749 1.13 33323 18175 3 1774.875983 592.6322 DNA replication licensing factor MCM7 OS=Homo sapiens OX=9606 GN=MCM7 PE=1 SV=4 4.32 3114.6 - 1.06E+06 - - - 0.6288 - 1.582 0.142 - 73.4 1 2 0 0.0011 14 0 0 0 1.53E+07 1.36E+07 - - - 1.3418 0.9987 221125_WJC_METTL3_EV_vs_WT_F03.18177.18177.3 0.000478 15/44 K.LALDVEIATYRK.L "sp|P48668|K2C6C_HUMAN,sp|Q01546|K22O_HUMAN,sp|P12035|K2C3_HUMAN,sp|P04259|K2C6B_HUMAN,sp|P13647|K2C5_HUMAN,sp|P35908|K22E_HUMAN,sp|O95678|K2C75_HUMAN,sp|Q5XKE5|K2C79_HUMAN,sp|P02538|K2C6A_HUMAN,tr|H0YI76|H0YI76_HUMAN,tr|H0YID6|H0YID6_HUMAN" 11 1390.782 999 33325 18177 3 1390.784156 464.6013 "Keratin, type II cytoskeletal 6C OS=Homo sapiens OX=9606 GN=KRT6C PE=1 SV=3" 6.07 3114.9 - 674786 - - - 1.5387 - 2.339 0.226 - 263 1 2 0 0.0021 12 0 0 0 9.56E+06 0.00E+00 - - - 3.4144 0.9994 221125_WJC_METTL3_EV_vs_WT_F03.18179.18179.3 0.000508 Sep-36 R.SHSIFLINVK[136.11].Q sp|P33176|KINH_HUMAN 1 1164.6746 1.75 33327 18179 3 1164.674044 389.2322 Kinesin-1 heavy chain OS=Homo sapiens OX=9606 GN=KIF5B PE=1 SV=1 8.49 3115.1 - 350575 - - - -0.5152 - 1.836 0.297 - 109.8 1 2 0 -0.0006 10 0 0 0 1.57E+07 8.99E+06 - - - 3.6255 0.9998 221125_WJC_METTL3_EV_vs_WT_F03.18181.18181.2 5.60E-05 22-Sep R.DIKPDNLLLDAK.G "sp|Q9Y2H1|ST38L_HUMAN,tr|F5H277|F5H277_HUMAN,tr|H0YGN4|H0YGN4_HUMAN" 3 1353.7504 2.21 33328 18181 2 1353.750741 677.8825 Serine\threonine-protein kinase 38-like OS=Homo sapiens OX=9606 GN=STK38L PE=1 SV=3 4.43 3115.3 - 5.24E+06 - - - 0.2659 - 1.924 0.443 - 110.7 1 2 0 0.0004 12 0 0 0 5.90E+07 2.67E+07 - - - 4.0347 0.9977 221125_WJC_METTL3_EV_vs_WT_F03.18185.18185.2 0.00274 22-Nov K.NIEIDSPYEISR[166.11].A "sp|P04843|RPN1_HUMAN,tr|B7Z4L4|B7Z4L4_HUMAN" 2 1444.7073 0.98 33332 18185 2 1444.700628 723.3609 Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit 1 OS=Homo sapiens OX=9606 GN=RPN1 PE=1 SV=1 4.14 3115.6 - 5.68E+06 - - - -4.6487 - 2.241 0.45 - 359.4 1 2 0 -0.0067 12 0 0 0 3.11E+07 3.16E+07 - - - 4.4857 0.9994 221125_WJC_METTL3_EV_vs_WT_F03.18186.18186.2 0.222 22-Nov K.SLELIQGEPLNK[136.11].D "sp|Q8IWZ3|ANKH1_HUMAN,tr|E9PDP5|E9PDP5_HUMAN" 2 1347.7489 1.63 33333 18186 2 1347.748794 674.8817 Ankyrin repeat and KH domain-containing protein 1 OS=Homo sapiens OX=9606 GN=ANKHD1 PE=1 SV=1 4.53 3115.6 - 3.29E+06 - - - -0.1017 - 2.027 0.263 - 205.9 1 2 0 -0.0001 12 0 0 0 7.78E+07 4.78E+07 - - - 2.8425 1 221125_WJC_METTL3_EV_vs_WT_F03.18190.18190.3 0.000172 18/44 K.AQLVEIVGC[160.03]HFR[166.11].S sp|O75446|SAP30_HUMAN 1 1437.7426 0.44 33337 18190 3 1437.742872 480.2548 Histone deacetylase complex subunit SAP30 OS=Homo sapiens OX=9606 GN=SAP30 PE=1 SV=1 6.78 3116.1 - 1.40E+06 - - - 0.1725 - 2.855 0.459 - 632 1 2 0 0.0002 12 0 0 0 1.74E+07 3.97E+07 - - - 6.5652 1 221125_WJC_METTL3_EV_vs_WT_F03.18194.18194.2 6.79E-10 17/24 K.TAFQEALDAAGDK.L sp|P10599|THIO_HUMAN 1 1335.6307 0.77 33339 18194 2 1335.621752 668.8226 Thioredoxin OS=Homo sapiens OX=9606 GN=TXN PE=1 SV=3 4.03 3116.6 - 1.98E+07 - - - -6.6695 - 2.831 0.689 - 699.6 1 2 0 -0.0089 13 0 0 0 3.79E+08 4.95E+08 - - - 6.798 0.8584 221125_WJC_METTL3_EV_vs_WT_F03.18195.18195.2 0.00774 20-Oct R.ETDFYLQSVER[166.11].G sp|Q9ULW3|ABT1_HUMAN 1 1395.6546 0.45 33340 18195 2 1396.653514 698.8346 Activator of basal transcription 1 OS=Homo sapiens OX=9606 GN=ABT1 PE=1 SV=1 4.14 3116.6 - 5.95E+06 - - - 715.7459 - 1.719 0.323 - 284.9 1 2 0 0.9989 11 0 0 0 1.88E+07 4.20E+07 - - - 2.5786 1 221125_WJC_METTL3_EV_vs_WT_F03.18197.18197.3 3.63E-06 17/48 K.QLAAAFHEEFVVR.E "sp|P51114|FXR1_HUMAN,tr|E7EU85|E7EU85_HUMAN,tr|E9PFF5|E9PFF5_HUMAN,tr|B4DXZ6|B4DXZ6_HUMAN" 4 1515.7834 1.11 33342 18197 3 1515.780989 506.2684 Fragile X mental retardation syndrome-related protein 1 OS=Homo sapiens OX=9606 GN=FXR1 PE=1 SV=3 5.4 3116.8 - 2.54E+06 - - - -1.5992 - 2.948 0.492 - 478.4 1 2 0 -0.0024 13 0 0 0 8.27E+07 7.44E+07 - - - 6.9559 1 221125_WJC_METTL3_EV_vs_WT_F03.18199.18199.3 9.27E-07 22/76 K.IIVDTYGGWGAHGGGAFSGK[136.11].D "sp|Q00266|METK1_HUMAN,sp|P31153|METK2_HUMAN" 2 1956.9574 1.22 33344 18199 3 1956.954623 653.3264 S-adenosylmethionine synthase isoform type-1 OS=Homo sapiens OX=9606 GN=MAT1A PE=1 SV=2 6.74 3117.1 - 1.24E+06 - - - -1.3991 - 3.454 0.56 - 435.3 1 2 0 -0.0027 20 0 0 0 1.96E+07 1.60E+07 - - - 7.7898 1 221125_WJC_METTL3_EV_vs_WT_F03.18201.18201.2 6.39E-07 14/34 R.ANVAVVSGAPLQGQLVAR.P sp|O00560|SDCB1_HUMAN 1 1748.9897 2.3 33346 18201 2 1748.985755 875.5021 Syntenin-1 OS=Homo sapiens OX=9606 GN=SDCBP PE=1 SV=1 9.79 3117.3 - 525364 - - - -2.2653 - 2.751 0.597 - 340.2 1 1 0 -0.004 18 0 0 0 3.58E+06 1.56E+06 - - - 5.9372 0.9895 221125_WJC_METTL3_EV_vs_WT_F03.18205.18205.2 0.00287 22-Nov K.NIEIDSPYEISR.A "sp|P04843|RPN1_HUMAN,tr|B7Z4L4|B7Z4L4_HUMAN" 2 1434.6991 0.98 33348 18205 2 1434.68951 718.3568 Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit 1 OS=Homo sapiens OX=9606 GN=RPN1 PE=1 SV=1 4.14 3117.9 - 3.04E+06 - - - -6.6662 - 2.108 0.443 - 369 1 2 0 -0.0096 12 0 0 0 3.11E+07 3.16E+07 - - - 4.2722 0.9933 221125_WJC_METTL3_EV_vs_WT_F03.18209.18209.2 1.56E-06 22-Dec V.ITVPAYFNDSQR[166.11].Q "sp|P38646|GRP75_HUMAN,sp|P54652|HSP72_HUMAN,sp|P0DMV8|HS71A_HUMAN,sp|P34931|HS71L_HUMAN,sp|P0DMV9|HS71B_HUMAN,sp|P17066|HSP76_HUMAN,tr|H0Y8K0|H0Y8K0_HUMAN,tr|A0A7I2V2S7|A0A7I2V2S7_HUMAN,tr|A0A7I2V2G2|A0A7I2V2G2_HUMAN,tr|Q53FA3|Q53FA3_HUMAN,tr|A0A7I2V3F7|A0A7I2V3F7_HUMAN,tr|A0A7I2YQB2|A0A7I2YQB2_HUMAN,tr|A0A0G2JIW1|A0A0G2JIW1_HUMAN,tr|D6RCD7|D6RCD7_HUMAN" 14 1419.7022 0.17 33352 18209 2 1419.700941 710.8584 "Stress-70 protein, mitochondrial OS=Homo sapiens OX=9606 GN=HSPA9 PE=1 SV=2" 5.84 3118.3 - 2.29E+06 - - - -0.8861 - 2.282 0.547 - 536 1 1 0 -0.0013 12 0 0 0 1.83E+07 1.10E+08 - - - 5.2516 1 221125_WJC_METTL3_EV_vs_WT_F03.18210.18210.3 1.50E-06 21/76 K.IIVDTYGGWGAHGGGAFSGK.D "sp|Q00266|METK1_HUMAN,sp|P31153|METK2_HUMAN" 2 1948.9432 1.27 33353 18210 3 1948.93827 650.655 S-adenosylmethionine synthase isoform type-1 OS=Homo sapiens OX=9606 GN=MAT1A PE=1 SV=2 6.74 3118.4 - 1.79E+06 - - - -2.5096 - 3.207 0.523 - 435.4 1 2 0 -0.0049 20 0 0 0 1.96E+07 1.54E+07 - - - 7.1967 1 221125_WJC_METTL3_EV_vs_WT_F03.18211.18211.3 2.05E-10 25/72 A.TAATAAAAAAAAYSDGYGR.V "sp|O43251|RFOX2_HUMAN,tr|B0QYV1|B0QYV1_HUMAN,tr|A0A0G2JRD1|A0A0G2JRD1_HUMAN,tr|A0A0G2JRA5|A0A0G2JRA5_HUMAN,tr|S4R3K7|S4R3K7_HUMAN" 5 1728.8067 1.91 33354 18211 3 1728.804201 577.2762 RNA binding protein fox-1 homolog 2 OS=Homo sapiens OX=9606 GN=RBFOX2 PE=1 SV=3 5.5 3118.6 - 908214 - - - -1.4611 - 3.45 0.647 - 590 1 1 0 -0.0025 19 0 0 0 2.22E+07 1.16E+07 - - - 8.7952 0.9996 221125_WJC_METTL3_EV_vs_WT_F03.18214.18214.3 0.03 13/44 R.YLYTLVITDK[136.11]EK[136.11].A "sp|P63173|RL38_HUMAN,tr|J3KT73|J3KT73_HUMAN,tr|J3QL01|J3QL01_HUMAN" 3 1500.841 2.41 33356 18214 3 1500.839191 501.2876 60S ribosomal protein L38 OS=Homo sapiens OX=9606 GN=RPL38 PE=1 SV=2 6.07 3118.8 - 3.41E+06 - - - -1.2366 - 2.347 0.399 - 152.5 1 2 1 -0.0019 12 0 0 0 2.38E+08 9.88E+07 - - - 5.3527 1 221125_WJC_METTL3_EV_vs_WT_F03.18217.18217.3 1.05E-09 17/48 K.VFGSDSALQIHLR[166.11].S "sp|Q9Y467|SALL2_HUMAN,sp|Q9NSC2|SALL1_HUMAN,sp|Q9BXA9|SALL3_HUMAN,tr|A0A087WXW6|A0A087WXW6_HUMAN,tr|A0A140TA74|A0A140TA74_HUMAN,tr|A0A140TA70|A0A140TA70_HUMAN,tr|F5H433|F5H433_HUMAN,tr|E7EW59|E7EW59_HUMAN,tr|H3BSM9|H3BSM9_HUMAN,tr|A9JR48|A9JR48_HUMAN,tr|H0YFS7|H0YFS7_HUMAN" 11 1451.776 1.24 33359 18217 3 1451.774917 484.9326 Sal-like protein 2 OS=Homo sapiens OX=9606 GN=SALL2 PE=1 SV=4 6.71 3119.1 - 2.11E+06 - - - -0.7687 - 3.211 0.438 - 305.5 1 2 0 -0.0011 13 0 0 0 4.28E+07 3.45E+07 - - - 6.5859 0.9999 221125_WJC_METTL3_EV_vs_WT_F03.18221.18221.3 2.52E-06 13/48 K.TAFQEALDAAGDK[136.11].L sp|P10599|THIO_HUMAN 1 1343.6449 0.46 33363 18221 3 1343.642044 448.8889 Thioredoxin OS=Homo sapiens OX=9606 GN=TXN PE=1 SV=3 4.03 3119.6 - 944244 - - - -2.0958 - 2.228 0.479 - 241.1 1 2 0 -0.0028 13 0 0 0 4.09E+06 8.89E+06 - - - 6.0516 1 221125_WJC_METTL3_EV_vs_WT_F03.18223.18223.3 3.88E-07 14/52 R.VPTANVSVVDLTC[160.03]R[166.11].L "sp|P04406|G3P_HUMAN,tr|E7EUT5|E7EUT5_HUMAN" 2 1539.7954 1.04 33364 18223 3 1539.792884 514.2724 Glyceraldehyde-3-phosphate dehydrogenase OS=Homo sapiens OX=9606 GN=GAPDH PE=1 SV=3 5.8 3119.8 - 1.29E+08 - - - -1.6652 - 2.43 0.525 - 344.3 1 2 0 -0.0026 14 0 0 0 1.95E+09 1.87E+09 - - - 6.7521 0.9999 221125_WJC_METTL3_EV_vs_WT_F03.18225.18225.3 4.12E-06 Dec-56 R.NFILDQTNVSAAAQR.R "sp|Q00839|HNRPU_HUMAN,tr|A0A1W2PQL0|A0A1W2PQL0_HUMAN,tr|A0A1W2PPL4|A0A1W2PPL4_HUMAN,tr|A0A1W2PQ74|A0A1W2PQ74_HUMAN,tr|Q5RI18|Q5RI18_HUMAN,tr|A0A1W2PP35|A0A1W2PP35_HUMAN,tr|A0A1W2PPS1|A0A1W2PPS1_HUMAN,tr|A0A1W2PRZ7|A0A1W2PRZ7_HUMAN,tr|A0A1W2PPH7|A0A1W2PPH7_HUMAN,tr|A0A1W2PQD4|A0A1W2PQD4_HUMAN,tr|A0A1W2PP34|A0A1W2PP34_HUMAN,tr|A0A1X7SBS1|A0A1X7SBS1_HUMAN" 12 1646.8376 1 33365 18225 3 1646.841607 549.9532 Heterogeneous nuclear ribonucleoprotein U OS=Homo sapiens OX=9606 GN=HNRNPU PE=1 SV=6 5.84 3120 - 6.60E+06 - - - 2.4131 - 2.425 0.453 - 200.1 1 2 0 0.004 15 0 0 0 4.22E+08 4.22E+08 - - - 5.9009 1 221125_WJC_METTL3_EV_vs_WT_F03.18226.18226.2 1.12E-06 16/22 R.TSGAFVYDC[160.03]SK[136.11]F.- sp|Q12948|FOXC1_HUMAN 1 1388.6162 2.72 33366 18226 2 1388.61236 695.3154 Forkhead box protein C1 OS=Homo sapiens OX=9606 GN=FOXC1 PE=1 SV=3 5.5 3120.1 - 3.30E+06 - - - -2.7675 - 3.082 0.629 - 1032.1 1 2 0 -0.0038 12 0 0 0 1.28E+08 4.70E+07 - - - 6.6472 1 221125_WJC_METTL3_EV_vs_WT_F03.18227.18227.2 5.83E-09 17/28 R.NFILDQTNVSAAAQR.R "sp|Q00839|HNRPU_HUMAN,tr|A0A1W2PQL0|A0A1W2PQL0_HUMAN,tr|A0A1W2PPL4|A0A1W2PPL4_HUMAN,tr|A0A1W2PQ74|A0A1W2PQ74_HUMAN,tr|Q5RI18|Q5RI18_HUMAN,tr|A0A1W2PP35|A0A1W2PP35_HUMAN,tr|A0A1W2PPS1|A0A1W2PPS1_HUMAN,tr|A0A1W2PRZ7|A0A1W2PRZ7_HUMAN,tr|A0A1W2PPH7|A0A1W2PPH7_HUMAN,tr|A0A1W2PQD4|A0A1W2PQD4_HUMAN,tr|A0A1W2PP34|A0A1W2PP34_HUMAN,tr|A0A1X7SBS1|A0A1X7SBS1_HUMAN" 12 1646.8376 1.02 33367 18227 2 1646.834752 824.4261 Heterogeneous nuclear ribonucleoprotein U OS=Homo sapiens OX=9606 GN=HNRNPU PE=1 SV=6 5.84 3120.1 - 1.11E+07 - - - -1.7494 - 3.376 0.59 - 1108.6 1 2 0 -0.0029 15 0 0 0 8.17E+08 8.04E+08 - - - 6.3891 0.9999 221125_WJC_METTL3_EV_vs_WT_F03.18228.18228.3 0.000144 17/44 K.AQLVEIVGC[160.03]HFR.S sp|O75446|SAP30_HUMAN 1 1427.7344 0.43 33368 18228 3 1427.731193 476.9187 Histone deacetylase complex subunit SAP30 OS=Homo sapiens OX=9606 GN=SAP30 PE=1 SV=1 6.78 3120.2 - 1.54E+06 - - - -2.214 - 2.957 0.47 - 613.1 1 2 0 -0.0032 12 0 0 0 1.72E+07 3.99E+07 - - - 6.7843 0.9999 221125_WJC_METTL3_EV_vs_WT_F03.18229.18229.2 0.00718 18-Dec R.FDAGELITQR.E "sp|P35232|PHB_HUMAN,tr|C9JZ20|C9JZ20_HUMAN,tr|E7ESE2|E7ESE2_HUMAN,tr|E9PCW0|E9PCW0_HUMAN,tr|C9JW96|C9JW96_HUMAN" 5 1148.5826 1.31 33369 18229 2 1148.581129 575.2986 Prohibitin OS=Homo sapiens OX=9606 GN=PHB PE=1 SV=1 4.37 3120.3 - 1.45E+06 - - - -1.2703 - 2.617 0.495 - 513.4 1 2 0 -0.0015 10 0 0 0 2.06E+08 1.58E+08 - - - 5.3819 0.9999 221125_WJC_METTL3_EV_vs_WT_F03.18232.18232.3 1.17E-05 13/44 R.MGDADYLAAWHR[166.11].L "sp|Q9UBN7|HDAC6_HUMAN,tr|A0A2R8YDE6|A0A2R8YDE6_HUMAN" 2 1414.6327 1.45 33372 18232 3 1414.628654 472.5515 Histone deacetylase 6 OS=Homo sapiens OX=9606 GN=HDAC6 PE=1 SV=2 5.19 3120.7 - 597110 - - - -2.8877 - 2.296 0.507 - 272.4 1 2 0 -0.0041 12 0 0 0 9.68E+06 6.65E+06 - - - 6.4953 0.9999 221125_WJC_METTL3_EV_vs_WT_F03.18239.18239.2 0.000842 16/24 K.QLSFISPPTPQPK.T sp|O43395|PRPF3_HUMAN 1 1438.782 2.9 33377 18239 2 1438.782633 720.3983 U4\U6 small nuclear ribonucleoprotein Prp3 OS=Homo sapiens OX=9606 GN=PRPF3 PE=1 SV=2 8.75 3121.3 - 2.10E+06 - - - 0.4288 - 2.87 0.521 - 928.3 1 2 0 0.0006 13 0 0 0 1.04E+08 3.61E+07 - - - 5.5948 0.9999 221125_WJC_METTL3_EV_vs_WT_F03.18241.18241.3 0.00169 Dec-44 R.MGDADYLAAWHR.L "sp|Q9UBN7|HDAC6_HUMAN,tr|A0A2R8YDE6|A0A2R8YDE6_HUMAN" 2 1404.6245 1.35 33379 18241 3 1404.623575 469.2154 Histone deacetylase 6 OS=Homo sapiens OX=9606 GN=HDAC6 PE=1 SV=2 5.19 3121.6 - 1.34E+06 - - - -0.6365 - 1.794 0.422 - 182.3 1 2 0 -0.0009 12 0 0 0 9.68E+06 7.19E+06 - - - 4.8646 1 221125_WJC_METTL3_EV_vs_WT_F03.18242.18242.3 0.000179 18/44 K.NSIEDIHAFAIR[166.11].S "sp|Q9NRY5|F1142_HUMAN,tr|E7ESJ7|E7ESJ7_HUMAN" 2 1394.7182 1.26 33380 18242 3 1394.719994 465.9133 Protein FAM114A2 OS=Homo sapiens OX=9606 GN=FAM114A2 PE=1 SV=4 5.32 3121.7 - 1.28E+06 - - - 1.2985 - 3.027 0.449 - 775.6 1 2 0 0.0018 12 0 0 0 7.63E+07 6.07E+07 - - - 6.6154 1 221125_WJC_METTL3_EV_vs_WT_F03.18243.18243.2 7.49E-09 15/28 K.LVSIGAEEIVDGNAK.M "sp|O43707|ACTN4_HUMAN,tr|F5GXS2|F5GXS2_HUMAN,tr|H7C144|H7C144_HUMAN" 3 1513.7988 0.86 33381 18243 2 1513.802055 757.9067 Alpha-actinin-4 OS=Homo sapiens OX=9606 GN=ACTN4 PE=1 SV=2 4.14 3121.8 - 1.23E+06 - - - 2.1581 - 2.893 0.623 - 741.8 1 2 0 0.0033 15 0 0 0 1.83E+07 2.13E+07 - - - 6.2532 0.9998 221125_WJC_METTL3_EV_vs_WT_F03.18244.18244.2 8.63E-07 13/22 K.DIPGLTDTTVPR[166.11].R "sp|P62753|RS6_HUMAN,tr|A2A3R5|A2A3R5_HUMAN" 2 1293.6804 1.06 33382 18244 2 1293.682429 647.8475 40S ribosomal protein S6 OS=Homo sapiens OX=9606 GN=RPS6 PE=1 SV=1 4.21 3121.9 - 1.23E+06 - - - 1.5676 - 2.297 0.499 - 668.8 1 2 0 0.002 12 0 0 0 1.25E+08 1.18E+08 - - - 4.9141 1 221125_WJC_METTL3_EV_vs_WT_F03.18245.18245.2 1.54E-08 14/24 K.TEMQDNTYPEILR[166.11].S sp|O43143|DHX15_HUMAN 1 1618.7536 1.46 33383 18245 2 1618.750146 810.3841 Pre-mRNA-splicing factor ATP-dependent RNA helicase DHX15 OS=Homo sapiens OX=9606 GN=DHX15 PE=1 SV=2 4.14 3122.1 - 1.12E+06 - - - -2.1597 - 3.1 0.66 - 769.7 1 2 0 -0.0035 13 0 0 0 3.52E+07 2.42E+07 - - - 6.8184 0.8869 221125_WJC_METTL3_EV_vs_WT_F03.18247.18247.2 1.71E-05 24-Nov R.SC[160.03]ENLAPFNTALK[136.11].L "sp|Q13155|AIMP2_HUMAN,tr|A8MU58|A8MU58_HUMAN" 2 1471.7221 0.82 33385 18247 2 1472.718896 736.8683 Aminoacyl tRNA synthase complex-interacting multifunctional protein 2 OS=Homo sapiens OX=9606 GN=AIMP2 PE=1 SV=2 5.72 3122.3 - 835030 - - - 677.3229 - 2.06 0.439 - 424.5 1 2 0 0.9968 13 0 0 0 2.36E+07 2.88E+07 - - - 3.8253 1 221125_WJC_METTL3_EV_vs_WT_F03.18250.18250.2 2.85E-08 13/22 R.TSGAFVYDC[160.03]SKF.- sp|Q12948|FOXC1_HUMAN 1 1380.602 2.72 33386 18250 2 1380.600481 691.3083 Forkhead box protein C1 OS=Homo sapiens OX=9606 GN=FOXC1 PE=1 SV=3 5.5 3122.7 - 9.58E+06 - - - -1.1024 - 2.802 0.543 - 753.3 1 2 0 -0.0015 12 0 0 0 1.28E+08 4.70E+07 - - - 5.7621 0.9999 221125_WJC_METTL3_EV_vs_WT_F03.18251.18251.2 0.00231 18-Nov R.FDAGELITQR[166.11].E "sp|P35232|PHB_HUMAN,tr|C9JZ20|C9JZ20_HUMAN,tr|E7ESE2|E7ESE2_HUMAN,tr|E9PCW0|E9PCW0_HUMAN,tr|C9JW96|C9JW96_HUMAN" 5 1158.5909 1.31 33387 18251 2 1158.589833 580.3027 Prohibitin OS=Homo sapiens OX=9606 GN=PHB PE=1 SV=1 4.37 3122.8 - 8.72E+06 - - - -0.8847 - 2.242 0.492 - 465.2 1 2 0 -0.001 10 0 0 0 2.06E+08 1.58E+08 - - - 4.9282 0.9996 221125_WJC_METTL3_EV_vs_WT_F03.18253.18253.2 6.92E-05 14-Aug K.DVEDMFSR.F "sp|Q15717|ELAV1_HUMAN,tr|M0R055|M0R055_HUMAN,tr|M0QZR9|M0QZR9_HUMAN" 3 997.4175 1.33 33389 18253 2 997.415799 499.716 ELAV-like protein 1 OS=Homo sapiens OX=9606 GN=ELAVL1 PE=1 SV=2 4.03 3122.9 - 5.09E+06 - - - -1.7014 - 1.638 0.451 - 207.7 1 2 0 -0.0017 8 0 0 0 7.66E+07 5.75E+07 - - - 3.8599 0.9993 221125_WJC_METTL3_EV_vs_WT_F03.18254.18254.3 0.00013 14/44 K.NSIEDIHAFAIR.S "sp|Q9NRY5|F1142_HUMAN,tr|E7ESJ7|E7ESJ7_HUMAN" 2 1384.7099 1.26 33390 18254 3 1384.706894 462.5772 Protein FAM114A2 OS=Homo sapiens OX=9606 GN=FAM114A2 PE=1 SV=4 5.32 3122.9 - 5.00E+06 - - - -2.1802 - 1.943 0.34 - 207.6 1 2 0 -0.003 12 0 0 0 7.63E+07 6.07E+07 - - - 4.171 0.9995 221125_WJC_METTL3_EV_vs_WT_F03.18255.18255.2 0.000396 14-Aug K.DVEDMFSR[166.11].F "sp|Q15717|ELAV1_HUMAN,tr|M0R055|M0R055_HUMAN,tr|M0QZR9|M0QZR9_HUMAN" 3 1007.4258 1.33 33391 18255 2 1007.423834 504.7202 ELAV-like protein 1 OS=Homo sapiens OX=9606 GN=ELAVL1 PE=1 SV=2 4.03 3123 - 4.33E+06 - - - -1.9178 - 1.519 0.492 - 209.7 1 2 0 -0.0019 8 0 0 0 7.66E+07 5.75E+07 - - - 3.9351 0.9997 221125_WJC_METTL3_EV_vs_WT_F03.18256.18256.2 0.000963 18-Dec R.LVQAFQFTDK[136.11].H "sp|Q06830|PRDX1_HUMAN,tr|A0A0A0MRQ5|A0A0A0MRQ5_HUMAN,tr|A0A0A0MSI0|A0A0A0MSI0_HUMAN" 3 1203.6379 0.57 33392 18256 2 1203.636039 602.8262 Peroxiredoxin-1 OS=Homo sapiens OX=9606 GN=PRDX1 PE=1 SV=1 5.84 3123.1 - 2.85E+06 - - - -1.5661 - 2.032 0.423 - 438.2 1 2 0 -0.0019 10 0 0 0 3.64E+07 6.37E+07 - - - 4.1438 0.9986 221125_WJC_METTL3_EV_vs_WT_F03.18257.18257.2 0.00426 20-Aug K.DIISDTSGDFR.K "sp|P07355|ANXA2_HUMAN,sp|A6NMY6|AXA2L_HUMAN,tr|H0YL33|H0YL33_HUMAN,tr|H0YMU9|H0YMU9_HUMAN,tr|H0YNA0|H0YNA0_HUMAN,tr|H0YM50|H0YM50_HUMAN,tr|H0YMD0|H0YMD0_HUMAN,tr|H0YMW4|H0YMW4_HUMAN,tr|H0YN42|H0YN42_HUMAN,tr|H0YN28|H0YN28_HUMAN,tr|H0YNP5|H0YNP5_HUMAN,tr|H0YNB8|H0YNB8_HUMAN,tr|H0YKS4|H0YKS4_HUMAN" 13 1224.5622 67.06 33393 18257 2 1224.560246 613.2884 Annexin A2 OS=Homo sapiens OX=9606 GN=ANXA2 PE=1 SV=2 3.93 3123.2 - 2.28E+06 - - - -1.6332 - 1.527 0.314 - 115.7 1 2 0 -0.002 11 0 0 0 2.78E+07 4.14E+05 - - - 2.5047 0.9998 221125_WJC_METTL3_EV_vs_WT_F03.18258.18258.2 4.89E-07 13/20 K.TLGDFAAEYAK[136.11].S "sp|P09874|PARP1_HUMAN,tr|A0A7I2V5E9|A0A7I2V5E9_HUMAN,tr|A0A7I2V625|A0A7I2V625_HUMAN,tr|A0A7I2V3E1|A0A7I2V3E1_HUMAN" 4 1192.5856 1.38 33394 18258 2 1192.583187 597.3001 Poly [ADP-ribose] polymerase 1 OS=Homo sapiens OX=9606 GN=PARP1 PE=1 SV=4 4.37 3123.3 - 1.94E+06 - - - -1.9848 - 2.018 0.552 - 329.9 1 2 0 -0.0024 11 0 0 0 3.49E+07 2.53E+07 - - - 5.0167 0.9998 221125_WJC_METTL3_EV_vs_WT_F03.18259.18259.2 0.000147 14/24 R.IESLSSQLSNLQK[136.11].E "sp|P20700|LMNB1_HUMAN,tr|E9PBF6|E9PBF6_HUMAN,tr|A0A0D9SFE5|A0A0D9SFE5_HUMAN" 3 1453.7868 1.19 33395 18259 2 1453.784481 727.9007 Lamin-B1 OS=Homo sapiens OX=9606 GN=LMNB1 PE=1 SV=2 6 3123.5 - 1.67E+06 - - - -1.5766 - 2.772 0.476 - 812 1 2 0 -0.0023 13 0 0 0 2.50E+07 2.10E+07 - - - 5.1728 0.9882 221125_WJC_METTL3_EV_vs_WT_F03.18264.18264.3 0.00219 Dec-56 K.IHYLDTTTLIEPAPR[166.11].Y sp|P46109|CRKL_HUMAN 1 1748.9337 0.23 33398 18264 3 1748.93384 583.9852 Crk-like protein OS=Homo sapiens OX=9606 GN=CRKL PE=1 SV=1 5.32 3124.1 - 3.34E+06 - - - 0.1052 - 1.93 0.13 - 133.4 1 2 0 0.0002 15 0 0 0 1.35E+07 5.81E+07 - - - 1.705 0.9998 221125_WJC_METTL3_EV_vs_WT_F03.18265.18265.3 0.002 18/56 R.IVSGIITPIHEQWEK[136.11].A "sp|Q92530|PSMF1_HUMAN,tr|Q5QPM7|Q5QPM7_HUMAN,tr|Q5QPM9|Q5QPM9_HUMAN" 3 1756.9603 1.48 33399 18265 3 1756.955208 586.6607 Proteasome inhibitor PI31 subunit OS=Homo sapiens OX=9606 GN=PSMF1 PE=1 SV=2 5.4 3124.2 - 2.40E+06 - - - -2.9101 - 2.945 0.405 - 281.6 1 2 0 -0.0051 15 0 0 0 5.14E+07 3.47E+07 - - - 5.8723 0.9983 221125_WJC_METTL3_EV_vs_WT_F03.18266.18266.3 0.903 Nov-44 K.ISIVR[166.11]PFSIETK[136.11].D "sp|O75410|TACC1_HUMAN,tr|E5RFM9|E5RFM9_HUMAN,tr|R4GMT7|R4GMT7_HUMAN" 3 1406.8252 0.88 33400 18266 3 1406.822795 469.949 Transforming acidic coiled-coil-containing protein 1 OS=Homo sapiens OX=9606 GN=TACC1 PE=1 SV=2 8.75 3124.3 - 2.81E+06 - - - -1.7245 - 2.109 0.234 - 156.2 1 2 0 -0.0024 12 0 0 0 3.58E+07 4.04E+07 - - - 3.2166 0.999 221125_WJC_METTL3_EV_vs_WT_F03.18267.18267.3 0.000121 15/36 M.VK[136.11]LFIGNLPR[166.11].E "sp|Q9BWF3|RBM4_HUMAN,sp|Q9BQ04|RBM4B_HUMAN,tr|E9PM61|E9PM61_HUMAN,tr|D6R9K7|D6R9K7_HUMAN,tr|J3QRR5|J3QRR5_HUMAN,tr|E9PB51|E9PB51_HUMAN,tr|U3KQD5|U3KQD5_HUMAN,tr|E9PLB0|E9PLB0_HUMAN" 8 1173.7353 1.38 33401 18267 3 1173.731737 392.2524 RNA-binding protein 4 OS=Homo sapiens OX=9606 GN=RBM4 PE=1 SV=1 11 3124.4 - 2.06E+06 - - - -3.022 - 2.472 0.413 - 289.8 1 2 1 -0.0035 10 0 0 0 7.58E+07 5.50E+07 - - - 5.7866 0.9399 221125_WJC_METTL3_EV_vs_WT_F03.18269.18269.2 0.27 24-Jul R.IVSAQSLAEDDVE.- sp|Q15388|TOM20_HUMAN 1 1374.6515 - 33403 18269 2 1374.644319 688.333 Mitochondrial import receptor subunit TOM20 homolog OS=Homo sapiens OX=9606 GN=TOMM20 PE=1 SV=1 3.7 3124.6 - 1.72E+06 - - - -5.1911 - 1.484 0.197 - 105.1 1 2 0 -0.0071 13 0 0 0 - - - - - 1.5069 0.9999 221125_WJC_METTL3_EV_vs_WT_F03.18275.18275.3 0.00436 15/44 R.ADLTEYLSTHYK[136.11].A sp|P31930|QCR1_HUMAN 1 1447.7075 1.24 33407 18275 3 1447.705955 483.5764 "Cytochrome b-c1 complex subunit 1, mitochondrial OS=Homo sapiens OX=9606 GN=UQCRC1 PE=1 SV=3" 5.32 3125.5 - 1.76E+06 - - - -1.0396 - 2.388 0.366 - 387.1 1 2 0 -0.0015 12 0 0 0 3.59E+07 2.90E+07 - - - 5.0329 0.9863 221125_WJC_METTL3_EV_vs_WT_F03.18277.18277.2 0.000718 18-Dec N.QSLLQPLNVK.V sp|P35908|K22E_HUMAN 1 1138.671 999 33409 18277 2 1138.66979 570.3428 "Keratin, type II cytoskeletal 2 epidermal OS=Homo sapiens OX=9606 GN=KRT2 PE=1 SV=2" 8.75 3125.6 - 6.29E+06 - - - -1.0705 - 2.259 0.387 - 468.5 1 1 0 -0.0012 10 0 0 0 1.00E+08 0.00E+00 - - - 4.1737 0.9998 221125_WJC_METTL3_EV_vs_WT_F03.18279.18279.2 8.01E-05 20-Nov R.SSSGLLEWESK[136.11].S "sp|P14866|HNRPL_HUMAN,tr|M0QYT0|M0QYT0_HUMAN,tr|A0A3B3ITJ4|A0A3B3ITJ4_HUMAN,tr|M0QXS5|M0QXS5_HUMAN,tr|M0R076|M0R076_HUMAN" 5 1229.6019 1.18 33411 18279 2 1229.600014 615.8082 Heterogeneous nuclear ribonucleoprotein L OS=Homo sapiens OX=9606 GN=HNRNPL PE=1 SV=2 4.53 3125.8 - 2.01E+06 - - - -1.5607 - 2.486 0.433 - 432.4 1 2 0 -0.0019 11 0 0 0 1.96E+08 1.65E+08 - - - 4.7021 0.9999 221125_WJC_METTL3_EV_vs_WT_F03.18280.18280.2 8.15E-06 20-Nov R.SSSGLLEWESK.S "sp|P14866|HNRPL_HUMAN,tr|M0QYT0|M0QYT0_HUMAN,tr|A0A3B3ITJ4|A0A3B3ITJ4_HUMAN,tr|M0QXS5|M0QXS5_HUMAN,tr|M0R076|M0R076_HUMAN" 5 1221.5877 1.18 33412 18280 2 1221.586775 611.8011 Heterogeneous nuclear ribonucleoprotein L OS=Homo sapiens OX=9606 GN=HNRNPL PE=1 SV=2 4.53 3125.9 - 1.93E+06 - - - -0.7842 - 2.542 0.464 - 515.2 1 2 0 -0.001 11 0 0 0 1.96E+08 1.65E+08 - - - 4.9917 1 221125_WJC_METTL3_EV_vs_WT_F03.18282.18282.2 4.22E-08 18/30 R.EAATSTLGGLGFSSER.N "sp|Q6W2J9|BCOR_HUMAN,tr|H7BZ37|H7BZ37_HUMAN,tr|H7C2V9|H7C2V9_HUMAN,tr|A0A5F9ZGX7|A0A5F9ZGX7_HUMAN,tr|H7BYY2|H7BYY2_HUMAN,tr|H7C231|H7C231_HUMAN" 6 1581.7635 1.06 33414 18282 2 1581.756436 791.889 BCL-6 corepressor OS=Homo sapiens OX=9606 GN=BCOR PE=1 SV=1 4.53 3126.2 - 1.69E+06 - - - -4.4438 - 3.422 0.573 - 862 1 2 0 -0.007 16 0 0 0 1.78E+07 1.67E+07 - - - 6.2955 0.9998 221125_WJC_METTL3_EV_vs_WT_F03.18284.18284.3 0.000118 Nov-40 K.LK[136.11]VPEWVDTVK[136.11].L "sp|P39019|RS19_HUMAN,tr|M0R140|M0R140_HUMAN,tr|M0R2L9|M0R2L9_HUMAN,tr|M0QYF7|M0QYF7_HUMAN" 4 1328.7675 1.14 33416 18284 3 1328.766519 443.9298 40S ribosomal protein S19 OS=Homo sapiens OX=9606 GN=RPS19 PE=1 SV=2 6.07 3126.4 - 979160 - - - -0.7292 - 2.205 0.483 - 179.8 1 2 1 -0.001 11 0 0 0 3.27E+09 2.86E+09 - - - 6.171 0.9997 221125_WJC_METTL3_EV_vs_WT_F03.18286.18286.3 2.14E-06 13/40 K.LKVPEWVDTVK.L "sp|P39019|RS19_HUMAN,tr|M0R140|M0R140_HUMAN,tr|M0R2L9|M0R2L9_HUMAN,tr|M0QYF7|M0QYF7_HUMAN" 4 1312.7391 1.14 33418 18286 3 1312.736378 438.587 40S ribosomal protein S19 OS=Homo sapiens OX=9606 GN=RPS19 PE=1 SV=2 6.07 3126.7 - 858028 - - - -2.0644 - 2.635 0.467 - 295.9 1 2 1 -0.0027 11 0 0 0 3.27E+09 2.86E+09 - - - 6.4983 1 221125_WJC_METTL3_EV_vs_WT_F03.18290.18290.3 6.80E-15 26/80 R.VTGEADVEFATHEEAVAAMSK.D sp|P52597|HNRPF_HUMAN 1 2191.0103 0.82 33420 18290 3 2191.009503 731.344 Heterogeneous nuclear ribonucleoprotein F OS=Homo sapiens OX=9606 GN=HNRNPF PE=1 SV=3 4.25 3127.1 - 4.43E+06 - - - -0.3701 - 5.285 0.722 - 802.8 1 2 0 -0.0008 21 0 0 0 7.26E+07 8.85E+07 - - - 10.5808 1 221125_WJC_METTL3_EV_vs_WT_F03.18291.18291.3 5.12E-07 Nov-44 R.ADLTEYLSTHYK.A sp|P31930|QCR1_HUMAN 1 1439.6933 1.24 33421 18291 3 1439.691578 480.905 "Cytochrome b-c1 complex subunit 1, mitochondrial OS=Homo sapiens OX=9606 GN=UQCRC1 PE=1 SV=3" 5.32 3127.2 - 3.34E+06 - - - -1.1683 - 2.596 0.521 - 239.6 1 2 0 -0.0017 12 0 0 0 3.59E+07 2.90E+07 - - - 6.9924 1 221125_WJC_METTL3_EV_vs_WT_F03.18292.18292.3 5.22E-06 17/52 K.DLANLEVPHELPTK.Q "sp|Q8WXI9|P66B_HUMAN,tr|A0A0U1RR34|A0A0U1RR34_HUMAN,tr|A0A0U1RRM1|A0A0U1RRM1_HUMAN,tr|A0A0U1RRK3|A0A0U1RRK3_HUMAN" 4 1574.8304 1.82 33422 18292 3 1574.830457 525.9508 Transcriptional repressor p66-beta OS=Homo sapiens OX=9606 GN=GATAD2B PE=1 SV=1 4.65 3127.2 - 3.61E+06 - - - 0.0222 - 2.708 0.482 - 246.1 1 2 0 0 14 0 0 0 6.04E+07 3.32E+07 - - - 6.5613 1 221125_WJC_METTL3_EV_vs_WT_F03.18294.18294.3 6.65E-06 16/56 K.TPIAAGHPSMNLLLR.K "sp|P50213|IDH3A_HUMAN,tr|H0YLI6|H0YLI6_HUMAN,tr|H0YKD0|H0YKD0_HUMAN,tr|H0YMU3|H0YMU3_HUMAN" 4 1589.8712 1.5 33424 18294 3 1589.871491 530.9643 "Isocitrate dehydrogenase [NAD] subunit alpha, mitochondrial OS=Homo sapiens OX=9606 GN=IDH3A PE=1 SV=1" 9.44 3127.3 - 2.62E+06 - - - 0.1944 - 3.066 0.438 - 336.8 1 2 0 0.0003 15 0 0 0 3.79E+07 2.53E+07 - - - 6.3466 0.8833 221125_WJC_METTL3_EV_vs_WT_F03.18295.18295.2 0.227 Oct-34 T.AGPADAPAGAVVGGGSPR[166.11].G "sp|Q10586|DBP_HUMAN,tr|M0QXP1|M0QXP1_HUMAN" 2 1515.7669 0.001 33425 18295 2 1515.766273 758.8907 D site-binding protein OS=Homo sapiens OX=9606 GN=DBP PE=1 SV=1 5.88 3127.5 - 1.39E+06 - - - -0.4295 - 1.589 0.21 - 125.1 1 1 0 -0.0007 18 0 0 0 0.00E+00 1.52E+07 - - - 1.7304 0.9971 221125_WJC_METTL3_EV_vs_WT_F03.18297.18297.2 0.00167 13/20 R.NLSEVPQC[160.03]VWR.L sp|Q9H9A6|LRC40_HUMAN 1 1386.6714 1.69 33427 18297 2 1386.664878 694.343 Leucine-rich repeat-containing protein 40 OS=Homo sapiens OX=9606 GN=LRRC40 PE=1 SV=1 5.99 3127.7 - 1.30E+06 - - - -4.7178 - 2.392 0.378 - 593.2 1 2 0 -0.0065 11 0 0 0 1.57E+07 9.32E+06 - - - 4.1902 0.9836 221125_WJC_METTL3_EV_vs_WT_F03.18298.18298.2 0.00284 24-Nov R.NALANPLYC[160.03]PDYR[166.11].L "sp|P22695|QCR2_HUMAN,tr|H3BP04|H3BP04_HUMAN,tr|H3BRG4|H3BRG4_HUMAN,tr|H3BSJ9|H3BSJ9_HUMAN" 4 1575.7379 1.73 33428 18298 2 1576.742974 788.8762 "Cytochrome b-c1 complex subunit 2, mitochondrial OS=Homo sapiens OX=9606 GN=UQCRC2 PE=1 SV=3" 5.83 3127.9 - 1.19E+06 - - - 637.8224 - 2.358 0.36 - 388 1 2 0 1.005 13 0 0 0 1.70E+07 9.84E+06 - - - 3.586 1 221125_WJC_METTL3_EV_vs_WT_F03.18300.18300.2 1.49E-07 14/24 R.GFETAYC[160.03]IDSMGK.T "sp|Q86SF2|GALT7_HUMAN,tr|H0YAK0|H0YAK0_HUMAN,tr|H0YAH3|H0YAH3_HUMAN" 3 1477.6218 0.62 33430 18300 2 1477.622922 739.8182 N-acetylgalactosaminyltransferase 7 OS=Homo sapiens OX=9606 GN=GALNT7 PE=1 SV=1 4.37 3128.1 - 1.14E+06 - - - 0.7918 - 2.557 0.661 - 601.5 1 2 0 0.0012 13 0 0 0 1.52E+07 2.45E+07 - - - 6.3323 1 221125_WJC_METTL3_EV_vs_WT_F03.18301.18301.2 1.45E-06 24-Nov R.GFETAYC[160.03]IDSMGK[136.11].T "sp|Q86SF2|GALT7_HUMAN,tr|H0YAK0|H0YAK0_HUMAN,tr|H0YAH3|H0YAH3_HUMAN" 3 1485.636 0.56 33431 18301 2 1485.639412 743.8253 N-acetylgalactosaminyltransferase 7 OS=Homo sapiens OX=9606 GN=GALNT7 PE=1 SV=1 4.37 3128.3 - 1.12E+06 - - - 2.329 - 2.27 0.65 - 350 1 2 0 0.0035 13 0 0 0 1.63E+07 2.90E+07 - - - 5.9448 1 221125_WJC_METTL3_EV_vs_WT_F03.18303.18303.2 3.39E-12 15/28 R.NPDDITNEEYGEFYK.S sp|P07900|HS90A_HUMAN 1 1832.7741 0.37 33433 18303 2 1832.76974 917.3943 Heat shock protein HSP 90-alpha OS=Homo sapiens OX=9606 GN=HSP90AA1 PE=1 SV=5 3.83 3128.5 - 694835 - - - -2.3729 - 3.23 0.744 - 338.5 1 2 0 -0.0043 15 0 0 0 2.28E+07 6.17E+07 - - - 7.4174 0.9999 221125_WJC_METTL3_EV_vs_WT_F03.18307.18307.2 4.19E-05 22-Nov K.DIPGLTDTTVPR.R "sp|P62753|RS6_HUMAN,tr|A2A3R5|A2A3R5_HUMAN" 2 1283.6721 1.06 33435 18307 2 1283.672375 642.8433 40S ribosomal protein S6 OS=Homo sapiens OX=9606 GN=RPS6 PE=1 SV=1 4.21 3129 - 7.06E+06 - - - 0.1901 - 2.203 0.505 - 452.2 1 2 0 0.0002 12 0 0 0 1.25E+08 1.18E+08 - - - 4.849 0.9904 221125_WJC_METTL3_EV_vs_WT_F03.18309.18309.2 0.00393 13/20 R.AVAQALEVIPR[166.11].T "sp|P49368|TCPG_HUMAN,tr|B4DUR8|B4DUR8_HUMAN" 2 1175.6902 0.16 33437 18309 2 1176.693441 588.8524 T-complex protein 1 subunit gamma OS=Homo sapiens OX=9606 GN=CCT3 PE=1 SV=4 6.05 3129.2 - 2.66E+06 - - - 853.3396 - 2.643 0.339 - 690.5 1 2 0 1.0033 11 0 0 0 6.30E+06 4.06E+07 - - - 3.8591 0.9995 221125_WJC_METTL3_EV_vs_WT_F03.18311.18311.3 0.00082 16/44 R.KLEAELLQIEER.H "sp|Q969G3|SMCE1_HUMAN,tr|A0A2R8Y855|A0A2R8Y855_HUMAN,tr|A0A2R8YES3|A0A2R8YES3_HUMAN,tr|A0A2U3TZQ7|A0A2U3TZQ7_HUMAN,tr|A0A2R8Y7U4|A0A2R8Y7U4_HUMAN,tr|B4DGM3|B4DGM3_HUMAN,tr|J3QKS7|J3QKS7_HUMAN,tr|A0A2R8Y4T4|A0A2R8Y4T4_HUMAN,tr|A0A2R8Y7I9|A0A2R8Y7I9_HUMAN,tr|J3QR61|J3QR61_HUMAN,tr|A0A2R8Y765|A0A2R8Y765_HUMAN" 11 1469.809 2.55 33439 18311 3 1469.807369 490.9436 SWI\SNF-related matrix-associated actin-dependent regulator of chromatin subfamily E member 1 OS=Homo sapiens OX=9606 GN=SMARCE1 PE=1 SV=2 4.49 3129.4 - 1.67E+06 - - - -1.0818 - 2.967 0.211 - 607.1 1 2 0 -0.0016 12 0 0 0 2.14E+07 8.39E+06 - - - 3.9065 0.9999 221125_WJC_METTL3_EV_vs_WT_F03.18312.18312.2 2.25E-05 13/24 K.QLSFISPPTPQPK[136.11].T sp|O43395|PRPF3_HUMAN 1 1446.7962 2.75 33440 18312 2 1446.796556 724.4054 U4\U6 small nuclear ribonucleoprotein Prp3 OS=Homo sapiens OX=9606 GN=PRPF3 PE=1 SV=2 8.75 3129.4 - 1.66E+06 - - - 0.235 - 2.362 0.498 - 534.5 1 2 0 0.0003 13 0 0 0 7.96E+07 2.90E+07 - - - 4.9251 0.9981 221125_WJC_METTL3_EV_vs_WT_F03.18314.18314.3 0.302 18/56 K.TPIAAGHPSMNLLLR[166.11].K "sp|P50213|IDH3A_HUMAN,tr|H0YLI6|H0YLI6_HUMAN,tr|H0YKD0|H0YKD0_HUMAN,tr|H0YMU3|H0YMU3_HUMAN" 4 1599.8795 1.49 33442 18314 3 1599.880748 534.3004 "Isocitrate dehydrogenase [NAD] subunit alpha, mitochondrial OS=Homo sapiens OX=9606 GN=IDH3A PE=1 SV=1" 9.44 3129.7 - 1.07E+06 - - - 0.8101 - 1.993 0.228 - 210.2 1 2 0 0.0013 15 0 0 0 3.77E+07 2.53E+07 - - - 2.8811 1 221125_WJC_METTL3_EV_vs_WT_F03.18315.18315.2 3.68E-13 18/30 R.YYTGVVNNNEMVALQR[166.11].D "sp|Q14527|HLTF_HUMAN,tr|A0A0C4DGA6|A0A0C4DGA6_HUMAN" 2 1879.9126 1.16 33443 18315 2 1879.911523 940.9636 Helicase-like transcription factor OS=Homo sapiens OX=9606 GN=HLTF PE=1 SV=2 6 3129.8 - 957833 - - - -0.5745 - 3.412 0.628 - 1132.5 1 2 0 -0.0011 16 0 0 0 1.30E+07 1.12E+07 - - - 6.6964 0.9996 221125_WJC_METTL3_EV_vs_WT_F03.18317.18317.3 0.000337 Nov-44 R.QLFHPEQLITGK[136.11].E "sp|Q9NY65|TBA8_HUMAN,sp|Q6PEY2|TBA3E_HUMAN,sp|P0DPH7|TBA3C_HUMAN,sp|Q71U36|TBA1A_HUMAN,sp|P0DPH8|TBA3D_HUMAN,sp|Q9H853|TBA4B_HUMAN,sp|P68366|TBA4A_HUMAN,sp|P68363|TBA1B_HUMAN,sp|Q9BQE3|TBA1C_HUMAN,tr|C9JJQ8|C9JJQ8_HUMAN,tr|F8VS66|F8VS66_HUMAN,tr|F8VWV9|F8VWV9_HUMAN,tr|F8VRZ4|F8VRZ4_HUMAN,tr|F8VVB9|F8VVB9_HUMAN,tr|C9JQ00|C9JQ00_HUMAN,tr|C9JEV8|C9JEV8_HUMAN,tr|A0A7P0TA31|A0A7P0TA31_HUMAN,tr|A0A1W2PQM2|A0A1W2PQM2_HUMAN,tr|F5H5D3|F5H5D3_HUMAN,tr|C9J2C0|C9J2C0_HUMAN,tr|C9K0S6|C9K0S6_HUMAN,tr|C9JDL2|C9JDL2_HUMAN,tr|F8VQQ4|F8VQQ4_HUMAN,tr|F8VX09|F8VX09_HUMAN,tr|A0A7P0T945|A0A7P0T945_HUMAN" 25 1417.7809 0.57 33445 18317 3 1417.781007 473.6009 Tubulin alpha-8 chain OS=Homo sapiens OX=9606 GN=TUBA8 PE=1 SV=1 6.75 3130.1 - 883978 - - - 0.0755 - 2.193 0.291 - 137.5 1 2 0 0.0001 12 0 0 0 3.44E+08 6.02E+08 - - - 3.961 1 221125_WJC_METTL3_EV_vs_WT_F03.18318.18318.2 1.51E-12 18/30 R.YYTGVVNNNEMVALQR.D "sp|Q14527|HLTF_HUMAN,tr|A0A0C4DGA6|A0A0C4DGA6_HUMAN" 2 1869.9043 1.16 33446 18318 2 1869.901623 935.9594 Helicase-like transcription factor OS=Homo sapiens OX=9606 GN=HLTF PE=1 SV=2 6 3130.2 - 858735 - - - -1.4493 - 3.499 0.717 - 1191.3 1 2 0 -0.0027 16 0 0 0 1.30E+07 1.12E+07 - - - 7.4152 0.9999 221125_WJC_METTL3_EV_vs_WT_F03.18320.18320.2 1.95E-05 26-Nov R.EWNLPPNAPAC[160.03]MER.Q sp|Q9BQA1|MEP50_HUMAN 1 1683.7497 3.4 33448 18320 2 1683.748647 842.8821 Methylosome protein 50 OS=Homo sapiens OX=9606 GN=WDR77 PE=1 SV=1 4.53 3130.5 - 549027 - - - -0.6527 - 1.804 0.61 - 290.3 1 2 0 -0.0011 14 0 0 0 8.01E+06 2.36E+06 - - - 5.0267 1 221125_WJC_METTL3_EV_vs_WT_F03.18322.18322.2 1.59E-07 13/22 R.LNVGGTYFVTTR.Q sp|Q14681|KCTD2_HUMAN 1 1326.6932 1.71 33449 18322 2 1326.692564 664.3539 BTB\POZ domain-containing protein KCTD2 OS=Homo sapiens OX=9606 GN=KCTD2 PE=1 SV=3 8.75 3130.7 - 5.14E+06 - - - -0.4801 - 2.664 0.556 - 589.6 1 2 0 -0.0006 12 0 0 0 6.41E+07 3.74E+07 - - - 5.7255 1 221125_WJC_METTL3_EV_vs_WT_F03.18324.18324.3 4.09E-08 13/52 R.SIAFHSAVSLDPIK[136.11].S sp|Q9Y3F4|STRAP_HUMAN 1 1491.8177 1.85 33450 18324 3 1491.816822 498.2798 Serine-threonine kinase receptor-associated protein OS=Homo sapiens OX=9606 GN=STRAP PE=1 SV=1 6.46 3130.9 - 7.59E+06 - - - -0.5745 - 2.681 0.592 - 116.8 1 2 0 -0.0009 14 0 0 0 1.03E+08 5.58E+07 - - - 7.7608 1 221125_WJC_METTL3_EV_vs_WT_F03.18326.18326.3 0.000132 13/52 R.SIAFHSAVSLDPIK.S sp|Q9Y3F4|STRAP_HUMAN 1 1483.8035 1.05 33452 18326 3 1483.802853 495.6084 Serine-threonine kinase receptor-associated protein OS=Homo sapiens OX=9606 GN=STRAP PE=1 SV=1 6.46 3131 - 6.00E+06 - - - -0.4219 - 2.544 0.523 - 120.9 1 2 0 -0.0006 14 0 0 0 5.50E+07 5.26E+07 - - - 6.8522 0.9999 221125_WJC_METTL3_EV_vs_WT_F03.18328.18328.3 0.00549 Oct-44 K.ISIVRPFSIETK.D "sp|O75410|TACC1_HUMAN,tr|E5RFM9|E5RFM9_HUMAN,tr|R4GMT7|R4GMT7_HUMAN" 3 1388.8028 0.88 33454 18328 3 1388.802139 463.9415 Transforming acidic coiled-coil-containing protein 1 OS=Homo sapiens OX=9606 GN=TACC1 PE=1 SV=2 8.75 3131.1 - 2.47E+06 - - - -0.4407 - 2.235 0.376 - 155.8 1 2 0 -0.0006 12 0 0 0 3.58E+07 4.04E+07 - - - 4.9611 0.9988 221125_WJC_METTL3_EV_vs_WT_F03.18329.18329.2 1.11E-05 13/24 K.GC[160.03]DVVVIPAGVPR.K sp|P40926|MDHM_HUMAN 1 1337.7126 3.19 33455 18329 2 1337.709276 669.8636 "Malate dehydrogenase, mitochondrial OS=Homo sapiens OX=9606 GN=MDH2 PE=1 SV=3" 5.83 3131.2 - 2.30E+06 - - - -2.4519 - 2.323 0.273 - 654.9 1 2 0 -0.0033 13 0 0 0 2.75E+07 8.61E+06 - - - 3.2196 1 221125_WJC_METTL3_EV_vs_WT_F03.18331.18331.3 0.00257 16/48 R.LPSYFVR[166.11]PDLGPK[136.11].M sp|Q7LBC6|KDM3B_HUMAN 1 1505.8361 2.66 33457 18331 3 1505.836979 502.9526 Lysine-specific demethylase 3B OS=Homo sapiens OX=9606 GN=KDM3B PE=1 SV=2 8.59 3131.4 - 2.13E+06 - - - 0.5704 - 2.845 0.46 - 490.3 1 2 0 0.0009 13 0 0 0 5.58E+07 2.09E+07 - - - 6.5031 1 221125_WJC_METTL3_EV_vs_WT_F03.18332.18332.3 1.90E-06 16/72 R.IGDLQAFQGHGAGNLAGLK[136.11].G "sp|P08195|4F2_HUMAN,tr|A0A7P0TAN7|A0A7P0TAN7_HUMAN,tr|J3KPF3|J3KPF3_HUMAN,tr|H0YH36|H0YH36_HUMAN,tr|A0A7P0TAT7|A0A7P0TAT7_HUMAN,tr|H0YFS2|H0YFS2_HUMAN,tr|A0A7P0T8U7|A0A7P0T8U7_HUMAN,tr|A0A7P0T8F1|A0A7P0T8F1_HUMAN,tr|A0A7P0Z4A0|A0A7P0Z4A0_HUMAN,tr|F5GZS6|F5GZS6_HUMAN,tr|A0A7P0Z4P5|A0A7P0Z4P5_HUMAN,tr|A0A7P0TAS6|A0A7P0TAS6_HUMAN" 12 1873.989 1.3 33458 18332 3 1873.989427 625.6703 4F2 cell-surface antigen heavy chain OS=Homo sapiens OX=9606 GN=SLC3A2 PE=1 SV=3 6.74 3131.5 - 2.12E+06 - - - 0.2305 - 3.049 0.533 - 250.7 1 2 0 0.0004 19 0 0 0 2.31E+07 1.78E+07 - - - 7.2212 0.9988 221125_WJC_METTL3_EV_vs_WT_F03.18333.18333.2 0.0194 18-Aug R.IQSLLDIQEK[136.11].E "sp|Q93009|UBP7_HUMAN,tr|A0A669KBL1|A0A669KBL1_HUMAN" 2 1193.6747 0.94 33459 18333 2 1193.673257 597.8446 Ubiquitin carboxyl-terminal hydrolase 7 OS=Homo sapiens OX=9606 GN=USP7 PE=1 SV=2 4.37 3131.5 - 1.91E+06 - - - -1.2122 - 1.792 0.239 - 136.7 1 2 0 -0.0014 10 0 0 0 1.73E+07 1.84E+07 - - - 2.4341 1 221125_WJC_METTL3_EV_vs_WT_F03.18334.18334.2 5.03E-08 16/28 R.C[160.03]FSPGVIEVQEVQGK[136.11].K "sp|O15160|RPAC1_HUMAN,tr|A0A2R8YEZ4|A0A2R8YEZ4_HUMAN,tr|A0A2R8Y5D3|A0A2R8Y5D3_HUMAN,tr|A0A2R8YEY5|A0A2R8YEY5_HUMAN" 4 1683.8382 0.22 33460 18334 2 1683.833708 842.9264 DNA-directed RNA polymerases I and III subunit RPAC1 OS=Homo sapiens OX=9606 GN=POLR1C PE=1 SV=1 4.53 3131.7 - 1.88E+06 - - - -2.6422 - 2.704 0.588 - 729.3 1 2 0 -0.0044 15 0 0 0 5.48E+06 2.53E+07 - - - 5.8282 0.9989 221125_WJC_METTL3_EV_vs_WT_F03.18335.18335.3 0.00894 Dec-44 R.LQEAC[160.03]KDILLFK.N "sp|P13861|KAP2_HUMAN,sp|P31323|KAP3_HUMAN,tr|H7C1L0|H7C1L0_HUMAN" 3 1476.801 0.24 33461 18335 3 1476.799776 493.2743 cAMP-dependent protein kinase type II-alpha regulatory subunit OS=Homo sapiens OX=9606 GN=PRKAR2A PE=1 SV=2 6.06 3131.7 - 1.79E+06 - - - -0.8539 - 2.422 0.309 - 175.9 1 2 1 -0.0013 12 0 0 0 1.22E+07 4.97E+07 - - - 4.4367 0.9993 221125_WJC_METTL3_EV_vs_WT_F03.18336.18336.2 0.00295 18-Oct R.IQSLLDIQEK.E "sp|Q93009|UBP7_HUMAN,tr|A0A669KBL1|A0A669KBL1_HUMAN" 2 1185.6605 0.97 33462 18336 2 1185.658007 593.8375 Ubiquitin carboxyl-terminal hydrolase 7 OS=Homo sapiens OX=9606 GN=USP7 PE=1 SV=2 4.37 3131.8 - 1.77E+06 - - - -2.106 - 2.153 0.316 - 208.3 1 2 0 -0.0025 10 0 0 0 1.73E+07 1.79E+07 - - - 3.5147 1 221125_WJC_METTL3_EV_vs_WT_F03.18337.18337.3 6.18E-07 15/44 R.EHALLAYTLGVK[136.11].Q "sp|Q05639|EF1A2_HUMAN,sp|P68104|EF1A1_HUMAN,sp|Q5VTE0|EF1A3_HUMAN,tr|A0A2R8Y488|A0A2R8Y488_HUMAN,tr|A0A7I2V659|A0A7I2V659_HUMAN,tr|A0A7I2V3H3|A0A7I2V3H3_HUMAN,tr|A0A2U3TZH3|A0A2U3TZH3_HUMAN,tr|A0A7I2V5N4|A0A7I2V5N4_HUMAN,tr|A0A087WVQ9|A0A087WVQ9_HUMAN,tr|A0A087WV01|A0A087WV01_HUMAN,tr|A0A2R8Y660|A0A2R8Y660_HUMAN" 11 1321.7485 1.86 33463 18337 3 1321.748782 441.5901 Elongation factor 1-alpha 2 OS=Homo sapiens OX=9606 GN=EEF1A2 PE=1 SV=1 6.85 3131.9 - 1.56E+06 - - - 0.1854 - 2.935 0.469 - 351.2 1 2 0 0.0002 12 0 0 0 2.61E+09 1.40E+09 - - - 6.7533 0.9786 221125_WJC_METTL3_EV_vs_WT_F03.18340.18340.2 0.201 20-Nov K.LKVPEWVDTVK.L "sp|P39019|RS19_HUMAN,tr|M0R140|M0R140_HUMAN,tr|M0R2L9|M0R2L9_HUMAN,tr|M0QYF7|M0QYF7_HUMAN" 4 1312.7391 2.7 33466 18340 2 1312.738874 657.3768 40S ribosomal protein S19 OS=Homo sapiens OX=9606 GN=RPS19 PE=1 SV=2 6.07 3132.3 - 920252 - - - -0.163 - 1.71 0.178 - 357.9 1 2 1 -0.0002 11 0 0 0 1.40E+08 5.18E+07 - - - 1.807 1 221125_WJC_METTL3_EV_vs_WT_F03.18341.18341.2 2.49E-14 22/38 K.AIGGEFSDTNAAVEGTPLPK[136.11].A "sp|O75410|TACC1_HUMAN,tr|E7EVI4|E7EVI4_HUMAN,tr|E5RJU4|E5RJU4_HUMAN,tr|E5RFM9|E5RFM9_HUMAN,tr|R4GMT7|R4GMT7_HUMAN,tr|H0YAY0|H0YAY0_HUMAN,tr|E7ET87|E7ET87_HUMAN" 7 1980.9884 1.63 33467 18341 2 1980.986859 991.5015 Transforming acidic coiled-coil-containing protein 1 OS=Homo sapiens OX=9606 GN=TACC1 PE=1 SV=2 4.14 3132.4 - 491590 - - - -0.7708 - 3.762 0.753 - 1181.1 1 2 0 -0.0015 20 0 0 0 1.95E+07 1.20E+07 - - - 7.8596 1 221125_WJC_METTL3_EV_vs_WT_F03.18342.18342.2 9.53E-14 21/38 K.AIGGEFSDTNAAVEGTPLPK.A "sp|O75410|TACC1_HUMAN,tr|E7EVI4|E7EVI4_HUMAN,tr|E5RJU4|E5RJU4_HUMAN,tr|E5RFM9|E5RFM9_HUMAN,tr|R4GMT7|R4GMT7_HUMAN,tr|H0YAY0|H0YAY0_HUMAN,tr|E7ET87|E7ET87_HUMAN" 7 1972.9742 1.63 33468 18342 2 1972.975837 987.4944 Transforming acidic coiled-coil-containing protein 1 OS=Homo sapiens OX=9606 GN=TACC1 PE=1 SV=2 4.14 3132.6 - 487617 - - - 0.8368 - 3.578 0.732 - 1203.3 1 2 0 0.0017 20 0 0 0 1.95E+07 1.20E+07 - - - 7.5812 0.9994 221125_WJC_METTL3_EV_vs_WT_F03.18348.18348.2 0.000185 18-Oct R.QAEVLAEFER.R sp|O43172|PRP4_HUMAN 1 1190.5932 0.95 33472 18348 2 1190.590637 596.3039 U4\U6 small nuclear ribonucleoprotein Prp4 OS=Homo sapiens OX=9606 GN=PRPF4 PE=1 SV=2 4.25 3133.2 - 2.86E+06 - - - -2.1124 - 1.807 0.421 - 313.5 1 2 0 -0.0025 10 0 0 0 1.76E+08 1.86E+08 - - - 3.8012 1 221125_WJC_METTL3_EV_vs_WT_F03.18349.18349.2 8.97E-10 15/22 R.EHALLAYTLGVK[136.11].Q "sp|Q05639|EF1A2_HUMAN,sp|P68104|EF1A1_HUMAN,sp|Q5VTE0|EF1A3_HUMAN,tr|A0A2R8Y488|A0A2R8Y488_HUMAN,tr|A0A7I2V659|A0A7I2V659_HUMAN,tr|A0A7I2V3H3|A0A7I2V3H3_HUMAN,tr|A0A2U3TZH3|A0A2U3TZH3_HUMAN,tr|A0A7I2V5N4|A0A7I2V5N4_HUMAN,tr|A0A087WVQ9|A0A087WVQ9_HUMAN,tr|A0A087WV01|A0A087WV01_HUMAN,tr|A0A2R8Y660|A0A2R8Y660_HUMAN" 11 1321.7485 0.87 33473 18349 2 1321.750644 661.8815 Elongation factor 1-alpha 2 OS=Homo sapiens OX=9606 GN=EEF1A2 PE=1 SV=1 6.85 3133.2 - 3.53E+06 - - - 1.5941 - 3.077 0.511 - 898.3 1 2 0 0.0021 12 0 0 0 4.66E+08 5.36E+08 - - - 5.7719 0.9894 221125_WJC_METTL3_EV_vs_WT_F03.18350.18350.3 0.000685 Oct-48 H.YLGEFSITYK[136.11]PVK[136.11].H "sp|P62841|RS15_HUMAN,tr|K7EM56|K7EM56_HUMAN,tr|A0A0B4J2B4|A0A0B4J2B4_HUMAN,tr|K7ELC2|K7ELC2_HUMAN,tr|K7EQJ5|K7EQJ5_HUMAN,tr|S4R417|S4R417_HUMAN" 6 1559.857 1.26 33474 18350 3 1559.855555 520.9596 40S ribosomal protein S15 OS=Homo sapiens OX=9606 GN=RPS15 PE=1 SV=2 8.43 3133.3 - 2.25E+06 - - - -0.9469 - 1.937 0.434 - 65.3 1 1 0 -0.0015 13 0 0 0 7.01E+07 5.56E+07 - - - 5.1708 0.9999 221125_WJC_METTL3_EV_vs_WT_F03.18351.18351.2 0.0144 15/26 R.EAALILGVSPTANK.G sp|Q96DA6|TIM14_HUMAN 1 1382.7769 1.12 33475 18351 2 1382.77743 692.3957 Mitochondrial import inner membrane translocase subunit TIM14 OS=Homo sapiens OX=9606 GN=DNAJC19 PE=1 SV=3 6.1 3133.4 - 2.22E+06 - - - 0.3616 - 2.895 0.397 - 883.8 1 2 0 0.0005 14 0 0 0 2.55E+07 2.28E+07 - - - 4.6406 0.9564 221125_WJC_METTL3_EV_vs_WT_F03.18352.18352.2 1.68 28-May R.LVIDTNFHTNDIAIR.A sp|Q8NHU2|CFA61_HUMAN 1 1740.9159 999 33476 18352 2 1740.916 871.4652 Cilia- and flagella-associated protein 61 OS=Homo sapiens OX=9606 GN=CFAP61 PE=2 SV=3 5.21 3133.6 - 2.17E+06 - - - 0.0672 - 1.059 0.082 - 55.7 2 2 0 0.0001 15 0 0 0 2.35E+07 0.00E+00 - - - -0.3469 0.9999 221125_WJC_METTL3_EV_vs_WT_F03.18353.18353.2 1.43E-06 20-Oct K.EDGAISTIVLR[166.11].G sp|P50990|TCPQ_HUMAN 1 1182.6484 13.92 33477 18353 2 1182.646862 592.3315 T-complex protein 1 subunit theta OS=Homo sapiens OX=9606 GN=CCT8 PE=1 SV=4 4.37 3133.6 - 2.15E+06 - - - -1.2768 - 2.134 0.54 - 338.5 1 2 0 -0.0015 11 0 0 0 4.98E+08 3.58E+07 - - - 5.0795 0.9998 221125_WJC_METTL3_EV_vs_WT_F03.18354.18354.3 0.00665 Nov-44 R.QLFHPEQLITGK.E "sp|Q9NY65|TBA8_HUMAN,sp|Q6PEY2|TBA3E_HUMAN,sp|P0DPH7|TBA3C_HUMAN,sp|Q71U36|TBA1A_HUMAN,sp|P0DPH8|TBA3D_HUMAN,sp|Q9H853|TBA4B_HUMAN,sp|P68366|TBA4A_HUMAN,sp|P68363|TBA1B_HUMAN,sp|Q9BQE3|TBA1C_HUMAN,tr|C9JJQ8|C9JJQ8_HUMAN,tr|F8VS66|F8VS66_HUMAN,tr|F8VWV9|F8VWV9_HUMAN,tr|F8VRZ4|F8VRZ4_HUMAN,tr|F8VVB9|F8VVB9_HUMAN,tr|C9JQ00|C9JQ00_HUMAN,tr|C9JEV8|C9JEV8_HUMAN,tr|A0A7P0TA31|A0A7P0TA31_HUMAN,tr|A0A1W2PQM2|A0A1W2PQM2_HUMAN,tr|F5H5D3|F5H5D3_HUMAN,tr|C9J2C0|C9J2C0_HUMAN,tr|C9K0S6|C9K0S6_HUMAN,tr|C9JDL2|C9JDL2_HUMAN,tr|F8VQQ4|F8VQQ4_HUMAN,tr|F8VX09|F8VX09_HUMAN,tr|A0A7P0T945|A0A7P0T945_HUMAN" 25 1409.7667 0.57 33478 18354 3 1409.766407 470.9295 Tubulin alpha-8 chain OS=Homo sapiens OX=9606 GN=TUBA8 PE=1 SV=1 6.75 3133.7 - 2.11E+06 - - - -0.2078 - 2.099 0.364 - 226.4 1 2 0 -0.0003 12 0 0 0 3.44E+08 6.02E+08 - - - 4.6534 0.9998 221125_WJC_METTL3_EV_vs_WT_F03.18355.18355.2 0.000758 13/26 R.EAALILGVSPTANK[136.11].G sp|Q96DA6|TIM14_HUMAN 1 1390.7911 1.12 33479 18355 2 1390.79118 696.4028 Mitochondrial import inner membrane translocase subunit TIM14 OS=Homo sapiens OX=9606 GN=DNAJC19 PE=1 SV=3 6.1 3133.8 - 2.00E+06 - - - 0.036 - 2.765 0.304 - 658.8 1 2 0 0.0001 14 0 0 0 2.55E+07 2.28E+07 - - - 3.8385 0.9998 221125_WJC_METTL3_EV_vs_WT_F03.18357.18357.2 1.25E-05 18-Oct R.SNFGYNIPLK.H "sp|P25788|PSA3_HUMAN,tr|G3V4X5|G3V4X5_HUMAN" 2 1151.5975 2.12 33481 18357 2 1151.596397 576.806 Proteasome subunit alpha type-3 OS=Homo sapiens OX=9606 GN=PSMA3 PE=1 SV=2 8.31 3134 - 1.75E+06 - - - -0.9656 - 1.925 0.48 - 365.1 1 2 0 -0.0011 10 0 0 0 2.83E+07 1.33E+07 - - - 4.414 1 221125_WJC_METTL3_EV_vs_WT_F03.18358.18358.3 1.03E-06 15/40 R.LSDQFHDILIR.K "sp|O75340|PDCD6_HUMAN,tr|A0A024QZ42|A0A024QZ42_HUMAN,tr|A0A087WZ38|A0A087WZ38_HUMAN,tr|H0Y9X3|H0Y9X3_HUMAN" 4 1355.7197 0.93 33482 18358 3 1355.719052 452.9139 Programmed cell death protein 6 OS=Homo sapiens OX=9606 GN=PDCD6 PE=1 SV=1 5.21 3134.1 - 1.73E+06 - - - -0.5149 - 2.864 0.511 - 645.7 1 2 0 -0.0007 11 0 0 0 1.53E+07 1.65E+07 - - - 7.2261 0.9999 221125_WJC_METTL3_EV_vs_WT_F03.18359.18359.2 1.32E-06 13/24 K.ILTTNTWSSELSK.L sp|O60701|UGDH_HUMAN 1 1478.7617 1.77 33483 18359 2 1478.761739 740.3881 UDP-glucose 6-dehydrogenase OS=Homo sapiens OX=9606 GN=UGDH PE=1 SV=1 6 3134.2 - 1.62E+06 - - - 0.044 - 2.477 0.564 - 480.9 1 2 0 0.0001 13 0 0 0 2.29E+07 1.30E+07 - - - 5.5346 1 221125_WJC_METTL3_EV_vs_WT_F03.18360.18360.3 1.89E-05 14/40 R.LSDQFHDILIR[166.11].K "sp|O75340|PDCD6_HUMAN,tr|A0A024QZ42|A0A024QZ42_HUMAN,tr|A0A087WZ38|A0A087WZ38_HUMAN,tr|H0Y9X3|H0Y9X3_HUMAN" 4 1365.728 0.93 33484 18360 3 1365.725553 456.2499 Programmed cell death protein 6 OS=Homo sapiens OX=9606 GN=PDCD6 PE=1 SV=1 5.21 3134.3 - 1.57E+06 - - - -1.8064 - 2.956 0.472 - 483.3 1 2 0 -0.0025 11 0 0 0 1.53E+07 1.65E+07 - - - 6.8806 1 221125_WJC_METTL3_EV_vs_WT_F03.18362.18362.2 3.69E-07 24/28 K.LVEALC[160.03]AEHQINLIK.V sp|P25398|RS12_HUMAN 1 1749.9447 1.9 33486 18362 2 1749.943242 875.9796 40S ribosomal protein S12 OS=Homo sapiens OX=9606 GN=RPS12 PE=1 SV=3 5.4 3134.5 - 1.37E+06 - - - -0.8566 - 4.787 0.632 - 2298.8 1 2 0 -0.0015 15 0 0 0 7.42E+07 3.91E+07 - - - 7.5583 1 221125_WJC_METTL3_EV_vs_WT_F03.18364.18364.2 1.07E-10 20/28 K.LVEALC[160.03]AEHQINLIK[136.11].V sp|P25398|RS12_HUMAN 1 1757.9589 1.91 33488 18364 2 1757.955085 879.9867 40S ribosomal protein S12 OS=Homo sapiens OX=9606 GN=RPS12 PE=1 SV=3 5.4 3134.8 - 828643 - - - -2.1935 - 4.349 0.584 - 1335.7 1 2 0 -0.0039 15 0 0 0 7.42E+07 3.88E+07 - - - 6.9671 1 221125_WJC_METTL3_EV_vs_WT_F03.18368.18368.2 2.98E-09 17/26 R.VPTANVSVVDLTC[160.03]R.L "sp|P04406|G3P_HUMAN,tr|E7EUT5|E7EUT5_HUMAN" 2 1529.7872 1.02 33491 18368 2 1529.788177 765.9009 Glyceraldehyde-3-phosphate dehydrogenase OS=Homo sapiens OX=9606 GN=GAPDH PE=1 SV=3 5.8 3135.2 - 2.17E+06 - - - 0.653 - 3.197 0.653 - 1008.9 1 2 0 0.001 14 0 0 0 8.36E+09 8.16E+09 - - - 6.7803 1 221125_WJC_METTL3_EV_vs_WT_F03.18369.18369.2 2.22E-08 20-Dec R.NPEAALSPTFR[166.11].S "sp|Q86U44|MTA70_HUMAN,tr|B4E349|B4E349_HUMAN,tr|F5H6D8|F5H6D8_HUMAN,tr|B4DTN4|B4DTN4_HUMAN" 4 1211.6174 3.35 33492 18369 2 1211.613883 606.816 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 6 3135.4 - 776929 - - - -2.9085 - 2.667 0.601 - 583.6 1 2 0 -0.0035 11 0 0 0 3.08E+07 9.20E+06 - - - 6.1326 0.9911 221125_WJC_METTL3_EV_vs_WT_F03.18371.18371.2 0.0169 24-Dec R.ALYDAELSQMQTH.L "sp|P48668|K2C6C_HUMAN,sp|P04259|K2C6B_HUMAN,sp|P02538|K2C6A_HUMAN" 3 1505.682 - 33494 18371 2 1505.680032 753.8483 "Keratin, type II cytoskeletal 6C OS=Homo sapiens OX=9606 GN=KRT6C PE=1 SV=3" 4.35 3135.4 - 7.67E+06 - - - -1.3363 - 2.606 0.489 - 384.8 1 1 0 -0.002 13 0 0 0 - - - - - 5.1104 0.9917 221125_WJC_METTL3_EV_vs_WT_F03.18375.18375.3 0.000134 Oct-48 R.ALYDAELSQMQTH.L "sp|P48668|K2C6C_HUMAN,sp|P04259|K2C6B_HUMAN,sp|P02538|K2C6A_HUMAN" 3 1505.682 - 33498 18375 3 1505.681931 502.9013 "Keratin, type II cytoskeletal 6C OS=Homo sapiens OX=9606 GN=KRT6C PE=1 SV=3" 4.35 3135.7 - 1.92E+06 - - - -0.075 - 1.809 0.473 - 123.5 1 1 0 -0.0001 13 0 0 0 - - - - - 5.4206 0.997 221125_WJC_METTL3_EV_vs_WT_F03.18376.18376.2 4.86E-05 20-Oct K.LK[136.11]VPEWVDTVK[136.11].L "sp|P39019|RS19_HUMAN,tr|M0R140|M0R140_HUMAN,tr|M0R2L9|M0R2L9_HUMAN,tr|M0QYF7|M0QYF7_HUMAN" 4 1328.7675 1.36 33499 18376 2 1328.766415 665.391 40S ribosomal protein S19 OS=Homo sapiens OX=9606 GN=RPS19 PE=1 SV=2 6.07 3135.8 - 1.65E+06 - - - -0.8075 - 1.959 0.406 - 293.3 1 2 1 -0.0011 11 0 0 0 7.52E+08 5.52E+08 - - - 3.8585 1 221125_WJC_METTL3_EV_vs_WT_F03.18377.18377.3 2.79E-06 18/56 R.FSSELEQIELHNSIR[166.11].D "sp|Q96EY4|TMA16_HUMAN,tr|H0Y9X1|H0Y9X1_HUMAN,tr|D6RA57|D6RA57_HUMAN" 3 1810.9089 2.29 33500 18377 3 1810.907451 604.6436 Translation machinery-associated protein 16 OS=Homo sapiens OX=9606 GN=TMA16 PE=1 SV=2 4.75 3135.9 - 1.61E+06 - - - -0.7985 - 2.899 0.479 - 562.2 1 2 0 -0.0014 15 0 0 0 1.09E+08 4.78E+07 - - - 6.6573 0.9999 221125_WJC_METTL3_EV_vs_WT_F03.18378.18378.2 0.00958 14/26 R.GGTLLSVTGEVEPR.G "sp|P33240|CSTF2_HUMAN,sp|Q9H0L4|CSTFT_HUMAN,tr|E9PID8|E9PID8_HUMAN,tr|E7EWR4|E7EWR4_HUMAN" 4 1413.7464 2.47 33501 18378 2 1413.745722 707.8805 Cleavage stimulation factor subunit 2 OS=Homo sapiens OX=9606 GN=CSTF2 PE=1 SV=1 4.53 3136 - 1.56E+06 - - - -0.4499 - 2.845 0.407 - 712.9 1 2 0 -0.0006 14 0 0 0 1.55E+08 6.27E+07 - - - 4.6707 0.9999 221125_WJC_METTL3_EV_vs_WT_F03.18380.18380.3 0.000657 Oct-36 R.MLNFNVPHIK.N "sp|Q8WVM8|SCFD1_HUMAN,tr|A0A7I2V414|A0A7I2V414_HUMAN,tr|A0A7I2V4U2|A0A7I2V4U2_HUMAN,tr|A0A7I2V4B8|A0A7I2V4B8_HUMAN,tr|J3KNG4|J3KNG4_HUMAN,tr|A0A7I2V5Z4|A0A7I2V5Z4_HUMAN,tr|A0A7I2V3C9|A0A7I2V3C9_HUMAN,tr|G3V5F3|G3V5F3_HUMAN,tr|A0A7I2V5I2|A0A7I2V5I2_HUMAN,tr|A0A7I2V590|A0A7I2V590_HUMAN,tr|A0A7I2V4B9|A0A7I2V4B9_HUMAN,tr|H0YJY1|H0YJY1_HUMAN,tr|H0YJS6|H0YJS6_HUMAN,tr|G3V363|G3V363_HUMAN,tr|A0A7I2YQR2|A0A7I2YQR2_HUMAN,tr|A0A7I2V362|A0A7I2V362_HUMAN,tr|A0A7I2V534|A0A7I2V534_HUMAN,tr|A0A7I2V3G4|A0A7I2V3G4_HUMAN,tr|A0A7I2V3B4|A0A7I2V3B4_HUMAN,tr|G3V2M8|G3V2M8_HUMAN,tr|A0A7I2V4R0|A0A7I2V4R0_HUMAN,tr|A0A7I2V5R9|A0A7I2V5R9_HUMAN,tr|G3V4I1|G3V4I1_HUMAN,tr|A0A7I2V3Y3|A0A7I2V3Y3_HUMAN,tr|G3V3K9|G3V3K9_HUMAN" 25 1211.6485 1.04 33503 18380 3 1211.64912 404.8901 Sec1 family domain-containing protein 1 OS=Homo sapiens OX=9606 GN=SCFD1 PE=1 SV=4 8.52 3136.3 - 1.18E+06 - - - 0.5125 - 1.832 0.414 - 159.7 1 2 0 0.0006 10 0 0 0 1.31E+07 1.27E+07 - - - 4.9236 1 221125_WJC_METTL3_EV_vs_WT_F03.18382.18382.2 1.48E-08 16/24 R.IGGNEGIDVPIPR[166.11].F "sp|Q96AE4|FUBP1_HUMAN,tr|E9PEB5|E9PEB5_HUMAN" 2 1345.7229 0.57 33505 18382 2 1345.722829 673.8687 Far upstream element-binding protein 1 OS=Homo sapiens OX=9606 GN=FUBP1 PE=1 SV=3 4.37 3136.5 - 1.00E+06 - - - -0.078 - 3.154 0.554 - 1169.6 1 2 0 -0.0001 13 0 0 0 7.64E+07 1.33E+08 - - - 6.0809 1 221125_WJC_METTL3_EV_vs_WT_F03.18384.18384.2 1.83E-10 15/34 K.PSTASAVPELATDPELEK[136.11].K "sp|Q86U44|MTA70_HUMAN,tr|B4E349|B4E349_HUMAN,tr|F5H6D8|F5H6D8_HUMAN,tr|H0YFV6|H0YFV6_HUMAN,tr|B4DTN4|B4DTN4_HUMAN" 5 1861.94 0.001 33507 18384 2 1861.939398 931.9773 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 4 3136.7 - 750856 - - - -0.3443 - 3.228 0.633 - 339.8 1 1 0 -0.0006 18 0 0 0 0.00E+00 7.66E+06 - - - 6.5972 0.991 221125_WJC_METTL3_EV_vs_WT_F03.18385.18385.2 0.0941 18-Oct K.ATLEVSSIIK[136.11].K "sp|Q9NP61|ARFG3_HUMAN,tr|B0QYV8|B0QYV8_HUMAN,tr|H0Y6A0|H0Y6A0_HUMAN" 3 1067.6318 1.27 33508 18385 2 1067.630945 534.8232 ADP-ribosylation factor GTPase-activating protein 3 OS=Homo sapiens OX=9606 GN=ARFGAP3 PE=1 SV=1 6.05 3136.9 - 517757 - - - -0.7784 - 1.663 0.058 - 172.7 2 2 0 -0.0008 10 0 0 0 8.87E+06 6.98E+06 - - - 0.7544 0.8954 221125_WJC_METTL3_EV_vs_WT_F03.18386.18386.3 1.54 Nov-44 K.ALLALPIRPATR.R sp|A6ZKI3|RTL8C_HUMAN 1 1290.8136 1.61 33509 18386 3 1290.814062 431.2785 Retrotransposon Gag-like protein 8C OS=Homo sapiens OX=9606 GN=RTL8C PE=1 SV=1 12 3137 - 444367 - - - 0.3649 - 1.746 0.059 - 198.4 5 2 0 0.0005 12 0 0 0 2.68E+07 1.67E+07 - - - 0.419 0.9986 221125_WJC_METTL3_EV_vs_WT_F03.18392.18392.3 1.15E-05 15/48 H.YLGEFSITYKPVK.H "sp|P62841|RS15_HUMAN,tr|K7EM56|K7EM56_HUMAN,tr|A0A0B4J2B4|A0A0B4J2B4_HUMAN,tr|K7ELC2|K7ELC2_HUMAN,tr|K7EQJ5|K7EQJ5_HUMAN,tr|S4R417|S4R417_HUMAN" 6 1543.8286 1.26 33513 18392 3 1543.82872 515.6168 40S ribosomal protein S15 OS=Homo sapiens OX=9606 GN=RPS15 PE=1 SV=2 8.43 3137.6 - 7.69E+06 - - - 0.057 - 2.535 0.598 - 164 1 1 0 0.0001 13 0 0 0 7.01E+07 5.56E+07 - - - 7.7291 0.9998 221125_WJC_METTL3_EV_vs_WT_F03.18396.18396.2 0.000381 18-Oct K.QVAEQFLNMR.G "sp|P22695|QCR2_HUMAN,tr|H3BRG4|H3BRG4_HUMAN,tr|H3BSJ9|H3BSJ9_HUMAN" 3 1234.6128 0.83 33517 18396 2 1234.611714 618.3137 "Cytochrome b-c1 complex subunit 2, mitochondrial OS=Homo sapiens OX=9606 GN=UQCRC2 PE=1 SV=3" 6 3137.8 - 2.21E+06 - - - -0.9136 - 2.001 0.468 - 485.1 1 2 0 -0.0011 10 0 0 0 1.84E+07 2.21E+07 - - - 4.4335 1 221125_WJC_METTL3_EV_vs_WT_F03.18397.18397.3 1.34E-09 21/80 R.VTGEADVEFATHEEAVAAMSK[136.11].D sp|P52597|HNRPF_HUMAN 1 2199.0245 0.83 33518 18397 3 2199.024944 734.0154 Heterogeneous nuclear ribonucleoprotein F OS=Homo sapiens OX=9606 GN=HNRNPF PE=1 SV=3 4.25 3137.9 - 2.11E+06 - - - 0.1955 - 4.447 0.636 - 397.2 1 2 0 0.0004 21 0 0 0 7.75E+07 9.37E+07 - - - 9.2082 0.9999 221125_WJC_METTL3_EV_vs_WT_F03.18398.18398.2 0.000127 16/26 R.TNPGYLLSPVTAQR[166.11].N "sp|O00443|P3C2A_HUMAN,tr|A0A0C4DGF9|A0A0C4DGF9_HUMAN" 2 1525.8128 1.97 33519 18398 2 1525.813229 763.9137 Phosphatidylinositol 4-phosphate 3-kinase C2 domain-containing subunit alpha OS=Homo sapiens OX=9606 GN=PIK3C2A PE=1 SV=2 8.41 3138 - 1.64E+06 - - - 0.2733 - 2.696 0.519 - 819.8 1 2 0 0.0004 14 0 0 0 5.00E+07 2.54E+07 - - - 5.363 0.9999 221125_WJC_METTL3_EV_vs_WT_F03.18401.18401.3 0.000107 Oct-36 R.MLNFNVPHIK[136.11].N "sp|Q8WVM8|SCFD1_HUMAN,tr|A0A7I2V414|A0A7I2V414_HUMAN,tr|A0A7I2V4U2|A0A7I2V4U2_HUMAN,tr|A0A7I2V4B8|A0A7I2V4B8_HUMAN,tr|J3KNG4|J3KNG4_HUMAN,tr|A0A7I2V5Z4|A0A7I2V5Z4_HUMAN,tr|A0A7I2V3C9|A0A7I2V3C9_HUMAN,tr|G3V5F3|G3V5F3_HUMAN,tr|A0A7I2V5I2|A0A7I2V5I2_HUMAN,tr|A0A7I2V590|A0A7I2V590_HUMAN,tr|A0A7I2V4B9|A0A7I2V4B9_HUMAN,tr|H0YJY1|H0YJY1_HUMAN,tr|H0YJS6|H0YJS6_HUMAN,tr|G3V363|G3V363_HUMAN,tr|A0A7I2YQR2|A0A7I2YQR2_HUMAN,tr|A0A7I2V362|A0A7I2V362_HUMAN,tr|A0A7I2V534|A0A7I2V534_HUMAN,tr|A0A7I2V3G4|A0A7I2V3G4_HUMAN,tr|A0A7I2V3B4|A0A7I2V3B4_HUMAN,tr|G3V2M8|G3V2M8_HUMAN,tr|A0A7I2V4R0|A0A7I2V4R0_HUMAN,tr|A0A7I2V5R9|A0A7I2V5R9_HUMAN,tr|G3V4I1|G3V4I1_HUMAN,tr|A0A7I2V3Y3|A0A7I2V3Y3_HUMAN,tr|G3V3K9|G3V3K9_HUMAN" 25 1219.6627 1.08 33522 18401 3 1219.662776 407.5615 Sec1 family domain-containing protein 1 OS=Homo sapiens OX=9606 GN=SCFD1 PE=1 SV=4 8.52 3138.3 - 1.01E+06 - - - 0.0631 - 1.939 0.404 - 147.2 1 2 0 0.0001 10 0 0 0 1.35E+07 1.25E+07 - - - 4.978 1 221125_WJC_METTL3_EV_vs_WT_F03.18404.18404.2 4.64E-09 14/28 R.FTAVEDQYYC[160.03]VDC[160.03]YK[136.11].N "sp|Q13642|FHL1_HUMAN,tr|A0A494C0D6|A0A494C0D6_HUMAN,tr|Q5JXI8|Q5JXI8_HUMAN" 3 1967.8161 0.87 33525 18404 2 1967.813479 984.9153 Four and a half LIM domains protein 1 OS=Homo sapiens OX=9606 GN=FHL1 PE=1 SV=4 4.03 3138.7 - 495371 - - - -1.3324 - 2.57 0.699 - 577.8 1 2 0 -0.0026 15 0 0 0 3.04E+06 3.49E+06 - - - 6.5236 1 221125_WJC_METTL3_EV_vs_WT_F03.18405.18405.2 2.97E-11 13/28 R.FTAVEDQYYC[160.03]VDC[160.03]YK.N "sp|Q13642|FHL1_HUMAN,tr|A0A494C0D6|A0A494C0D6_HUMAN,tr|Q5JXI8|Q5JXI8_HUMAN" 3 1959.8019 0.87 33526 18405 2 1959.801834 980.9082 Four and a half LIM domains protein 1 OS=Homo sapiens OX=9606 GN=FHL1 PE=1 SV=4 4.03 3138.9 - 342565 - - - -0.0342 - 2.558 0.802 - 449.9 1 2 0 -0.0001 15 0 0 0 3.04E+06 3.49E+06 - - - 7.2737 1 221125_WJC_METTL3_EV_vs_WT_F03.18408.18408.3 7.45E-06 16/60 R.DMLGGNGISDEYHVIR.H "sp|Q92947|GCDH_HUMAN,tr|K7ESA6|K7ESA6_HUMAN,tr|K7EQ99|K7EQ99_HUMAN" 3 1774.8308 1.52 33527 18408 3 1774.828768 592.6176 "Glutaryl-CoA dehydrogenase, mitochondrial OS=Homo sapiens OX=9606 GN=GCDH PE=1 SV=1" 4.54 3139.3 - 3.30E+06 - - - -1.1635 - 2.816 0.526 - 279.7 1 2 0 -0.0021 16 0 0 0 5.86E+07 3.87E+07 - - - 7.0603 0.9998 221125_WJC_METTL3_EV_vs_WT_F03.18409.18409.2 0.000127 13/26 R.GGTLLSVTGEVEPR[166.11].G "sp|P33240|CSTF2_HUMAN,sp|Q9H0L4|CSTFT_HUMAN,tr|E9PID8|E9PID8_HUMAN,tr|E7EWR4|E7EWR4_HUMAN" 4 1423.7546 2.47 33528 18409 2 1423.753099 712.8846 Cleavage stimulation factor subunit 2 OS=Homo sapiens OX=9606 GN=CSTF2 PE=1 SV=1 4.53 3139.3 - 3.22E+06 - - - -1.0739 - 2.477 0.452 - 624.8 1 2 0 -0.0015 14 0 0 0 1.55E+08 6.27E+07 - - - 4.6552 0.9999 221125_WJC_METTL3_EV_vs_WT_F03.18411.18411.2 0.174 15/22 K.TDTESELDLISR.L "sp|P11586|C1TC_HUMAN,tr|F5H2F4|F5H2F4_HUMAN,tr|V9GZ78|V9GZ78_HUMAN,tr|V9GYY3|V9GYY3_HUMAN,tr|A0A494C1T2|A0A494C1T2_HUMAN" 5 1377.6624 1.83 33530 18411 2 1377.660628 689.8385 "C-1-tetrahydrofolate synthase, cytoplasmic OS=Homo sapiens OX=9606 GN=MTHFD1 PE=1 SV=4" 3.92 3139.5 - 2.26E+06 - - - -1.2528 - 2.856 0.517 - 685.9 1 2 0 -0.0017 12 0 0 0 1.42E+08 7.77E+07 - - - 5.6202 0.9998 221125_WJC_METTL3_EV_vs_WT_F03.18414.18414.3 0.000103 13/44 R.GSPHYFSPFRPY.- sp|Q13242|SRSF9_HUMAN 1 1453.6779 1.41 33533 18414 3 1453.674887 485.5666 Serine\arginine-rich splicing factor 9 OS=Homo sapiens OX=9606 GN=SRSF9 PE=1 SV=1 8.6 3139.9 - 1.08E+06 - - - -2.0624 - 2.278 0.403 - 292.3 1 2 0 -0.003 12 0 0 0 1.59E+07 1.12E+07 - - - 5.3143 1 221125_WJC_METTL3_EV_vs_WT_F03.18415.18415.2 0.000329 14/26 K.MVAYLQDSALDDER[166.11].L "sp|Q6Y7W6|GGYF2_HUMAN,tr|A0A7I2V3H7|A0A7I2V3H7_HUMAN,tr|I1E4Y6|I1E4Y6_HUMAN,tr|A0A7I2V516|A0A7I2V516_HUMAN,tr|A0A7I2V3H0|A0A7I2V3H0_HUMAN,tr|C9JHW1|C9JHW1_HUMAN,tr|A0A7I2V361|A0A7I2V361_HUMAN,tr|E7ESB6|E7ESB6_HUMAN" 8 1634.7486 5.29 33534 18415 2 1634.747677 818.3816 GRB10-interacting GYF protein 2 OS=Homo sapiens OX=9606 GN=GIGYF2 PE=1 SV=1 3.84 3140 - 1.05E+06 - - - -0.5383 - 3.171 0.605 - 758.1 1 2 0 -0.0009 14 0 0 0 5.32E+07 1.01E+07 - - - 6.4053 0.9999 221125_WJC_METTL3_EV_vs_WT_F03.18418.18418.3 1.54E-05 13/52 K.IAILTC[160.03]PFEPPKPK.T "sp|P48643|TCPE_HUMAN,tr|E9PCA1|E9PCA1_HUMAN,tr|B7ZAR1|B7ZAR1_HUMAN,tr|E7ENZ3|E7ENZ3_HUMAN" 4 1609.8902 0.66 33537 18418 3 1609.889202 537.6373 T-complex protein 1 subunit epsilon OS=Homo sapiens OX=9606 GN=CCT5 PE=1 SV=1 8.2 3140.4 - 716542 - - - -0.6112 - 2.345 0.399 - 186.2 1 2 0 -0.001 14 0 0 0 6.82E+06 1.03E+07 - - - 5.2532 0.9864 221125_WJC_METTL3_EV_vs_WT_F03.18420.18420.2 3.53E-05 24-Sep H.YLGEFSITYK[136.11]PVK[136.11].H "sp|P62841|RS15_HUMAN,tr|K7EM56|K7EM56_HUMAN,tr|A0A0B4J2B4|A0A0B4J2B4_HUMAN,tr|K7ELC2|K7ELC2_HUMAN,tr|K7EQJ5|K7EQJ5_HUMAN,tr|S4R417|S4R417_HUMAN" 6 1559.857 1.08 33539 18420 2 1559.857787 780.9358 40S ribosomal protein S15 OS=Homo sapiens OX=9606 GN=RPS15 PE=1 SV=2 8.43 3140.7 - 471766 - - - 0.484 - 1.647 0.499 - 182.7 1 1 0 0.0008 13 0 0 0 5.04E+06 4.67E+06 - - - 4.007 1 221125_WJC_METTL3_EV_vs_WT_F03.18423.18423.2 2.78E-10 15/26 K.MVAYLQDSALDDER.L "sp|Q6Y7W6|GGYF2_HUMAN,tr|A0A7I2V3H7|A0A7I2V3H7_HUMAN,tr|I1E4Y6|I1E4Y6_HUMAN,tr|A0A7I2V516|A0A7I2V516_HUMAN,tr|A0A7I2V3H0|A0A7I2V3H0_HUMAN,tr|C9JHW1|C9JHW1_HUMAN,tr|A0A7I2V361|A0A7I2V361_HUMAN,tr|E7ESB6|E7ESB6_HUMAN" 8 1624.7403 3.91 33540 18423 2 1624.737933 813.3774 GRB10-interacting GYF protein 2 OS=Homo sapiens OX=9606 GN=GIGYF2 PE=1 SV=1 3.84 3141.1 - 4.94E+06 - - - -1.4488 - 2.832 0.697 - 979.4 1 2 0 -0.0024 14 0 0 0 5.80E+07 1.49E+07 - - - 6.8006 1 221125_WJC_METTL3_EV_vs_WT_F03.18424.18424.2 3.84E-07 21/32 R.ALLEAGALPNAPNSYGR.R "sp|P42771|CDN2A_HUMAN,tr|J3QRG6|J3QRG6_HUMAN" 2 1712.8846 2.53 33541 18424 2 1712.882671 857.4496 Cyclin-dependent kinase inhibitor 2A OS=Homo sapiens OX=9606 GN=CDKN2A PE=1 SV=2 6.05 3141.2 - 3.02E+06 - - - -1.1162 - 3.74 0.514 - 919.9 1 2 0 -0.0019 17 0 0 0 2.45E+08 9.71E+07 - - - 6.0798 1 221125_WJC_METTL3_EV_vs_WT_F03.18425.18425.3 1.82E-06 19/64 R.ALLEAGALPNAPNSYGR.R "sp|P42771|CDN2A_HUMAN,tr|J3QRG6|J3QRG6_HUMAN" 2 1712.8846 2.29 33542 18425 3 1712.883047 571.9688 Cyclin-dependent kinase inhibitor 2A OS=Homo sapiens OX=9606 GN=CDKN2A PE=1 SV=2 6.05 3141.3 - 1.64E+06 - - - -0.8967 - 3.06 0.419 - 494.2 1 2 0 -0.0015 17 0 0 0 9.33E+07 4.07E+07 - - - 6.0365 0.9999 221125_WJC_METTL3_EV_vs_WT_F03.18426.18426.2 0.000293 20/32 R.ALLEAGALPNAPNSYGR[166.11].R "sp|P42771|CDN2A_HUMAN,tr|J3QRG6|J3QRG6_HUMAN" 2 1722.8929 2.53 33543 18426 2 1722.894607 862.4537 Cyclin-dependent kinase inhibitor 2A OS=Homo sapiens OX=9606 GN=CDKN2A PE=1 SV=2 6.05 3141.5 - 1.61E+06 - - - 1.0181 - 3.494 0.431 - 868.5 1 2 0 0.0018 17 0 0 0 2.45E+08 9.71E+07 - - - 5.2996 0.9997 221125_WJC_METTL3_EV_vs_WT_F03.18428.18428.2 4.94E-05 20-Oct K.GFNPAQPLNIR.M "sp|Q12769|NU160_HUMAN,tr|E9PR16|E9PR16_HUMAN,tr|G3V198|G3V198_HUMAN" 3 1225.6568 2.09 33545 18428 2 1225.655871 613.8357 Nuclear pore complex protein Nup160 OS=Homo sapiens OX=9606 GN=NUP160 PE=1 SV=3 9.75 3141.7 - 1.19E+06 - - - -0.7212 - 1.979 0.377 - 278.1 1 2 0 -0.0009 11 0 0 0 1.26E+07 6.02E+06 - - - 3.6718 0.9997 221125_WJC_METTL3_EV_vs_WT_F03.18429.18429.2 0.000134 18-Nov K.QVAEQFLNMR[166.11].G "sp|P22695|QCR2_HUMAN,tr|H3BRG4|H3BRG4_HUMAN,tr|H3BSJ9|H3BSJ9_HUMAN" 3 1244.6211 0.94 33546 18429 2 1244.618736 623.3178 "Cytochrome b-c1 complex subunit 2, mitochondrial OS=Homo sapiens OX=9606 GN=UQCRC2 PE=1 SV=3" 6 3141.8 - 1.17E+06 - - - -1.909 - 2.361 0.454 - 384.5 1 2 0 -0.0024 10 0 0 0 1.83E+07 1.95E+07 - - - 4.7915 0.997 221125_WJC_METTL3_EV_vs_WT_F03.18430.18430.3 0.0262 15/52 R.TNPGYLLSPVTAQR[166.11].N "sp|O00443|P3C2A_HUMAN,tr|A0A0C4DGF9|A0A0C4DGF9_HUMAN" 2 1525.8128 3.34 33547 18430 3 1525.806848 509.6115 Phosphatidylinositol 4-phosphate 3-kinase C2 domain-containing subunit alpha OS=Homo sapiens OX=9606 GN=PIK3C2A PE=1 SV=2 8.41 3141.9 - 756658 - - - -3.9087 - 2.241 0.296 - 235.5 1 2 0 -0.006 14 0 0 0 1.97E+07 5.90E+06 - - - 3.9829 0.9921 221125_WJC_METTL3_EV_vs_WT_F03.18435.18435.3 0.172 Dec-48 R.VEYHFLSPYVSPK[136.11].E "sp|P02786|TFR1_HUMAN,tr|G3V0E5|G3V0E5_HUMAN" 2 1572.8068 0.99 33550 18435 3 1572.806902 525.2762 Transferrin receptor protein 1 OS=Homo sapiens OX=9606 GN=TFRC PE=1 SV=2 6.72 3142.6 - 4.00E+06 - - - 0.0776 - 1.612 0.19 - 55.9 1 2 0 0.0001 13 0 0 0 4.02E+07 4.07E+07 - - - 1.9529 0.9999 221125_WJC_METTL3_EV_vs_WT_F03.18436.18436.2 1.85E-07 13/28 K.SSGVPVDGFYTEEVR[166.11].Q "sp|Q9BSD7|NTPCR_HUMAN,tr|Q5TDF0|Q5TDF0_HUMAN" 2 1650.7765 1.18 33551 18436 2 1650.774801 826.3955 Cancer-related nucleoside-triphosphatase OS=Homo sapiens OX=9606 GN=NTPCR PE=1 SV=1 4.14 3142.7 - 2.80E+06 - - - -1.0207 - 2.374 0.575 - 453.2 1 2 0 -0.0017 15 0 0 0 1.54E+09 1.31E+09 - - - 5.413 0.9993 221125_WJC_METTL3_EV_vs_WT_F03.18438.18438.3 0.000475 13/48 R.VEYHFLSPYVSPK.E "sp|P02786|TFR1_HUMAN,tr|G3V0E5|G3V0E5_HUMAN" 2 1564.7926 1.01 33553 18438 3 1564.793225 522.6048 Transferrin receptor protein 1 OS=Homo sapiens OX=9606 GN=TFRC PE=1 SV=2 6.72 3142.8 - 2.57E+06 - - - 0.4122 - 2.506 0.227 - 182.2 1 2 0 0.0006 13 0 0 0 4.10E+07 4.07E+07 - - - 3.5615 1 221125_WJC_METTL3_EV_vs_WT_F03.18439.18439.2 3.36E-08 13/28 K.SSGVPVDGFYTEEVR.Q "sp|Q9BSD7|NTPCR_HUMAN,tr|Q5TDF0|Q5TDF0_HUMAN" 2 1640.7682 1.18 33554 18439 2 1640.766691 821.3914 Cancer-related nucleoside-triphosphatase OS=Homo sapiens OX=9606 GN=NTPCR PE=1 SV=1 4.14 3142.9 - 1.90E+06 - - - -0.9294 - 2.364 0.658 - 359.2 1 2 0 -0.0015 15 0 0 0 1.54E+09 1.31E+09 - - - 6.0157 0.986 221125_WJC_METTL3_EV_vs_WT_F03.18440.18440.2 0.00393 18-Oct K.LLHHLSDLAL.T "sp|Q86U44|MTA70_HUMAN,tr|B4E349|B4E349_HUMAN,tr|F5H6D8|F5H6D8_HUMAN,tr|H0YFV6|H0YFV6_HUMAN,tr|B4DTN4|B4DTN4_HUMAN" 5 1130.6448 - 33555 18440 2 1130.644534 566.3297 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 5.97 3143.1 - 1.77E+06 - - - -0.23 - 2.019 0.387 - 238.4 1 1 0 -0.0003 10 0 0 0 - - - - - 3.8605 0.9633 221125_WJC_METTL3_EV_vs_WT_F03.18442.18442.2 0.0562 18-Aug K.DQGGELLSLR[166.11].Y "sp|P49590|SYHM_HUMAN,sp|P12081|HARS1_HUMAN,tr|A0A6Q8PF47|A0A6Q8PF47_HUMAN,tr|A0A2R8Y5P7|A0A2R8Y5P7_HUMAN,tr|A0A6Q8PF07|A0A6Q8PF07_HUMAN,tr|A0A2R8Y5E8|A0A2R8Y5E8_HUMAN,tr|A0A2R8Y6I1|A0A2R8Y6I1_HUMAN,tr|A0A6Q8PHA5|A0A6Q8PHA5_HUMAN,tr|E7ETE2|E7ETE2_HUMAN,tr|A0A2R8Y3N3|A0A2R8Y3N3_HUMAN,tr|A0A6Q8PFF2|A0A6Q8PFF2_HUMAN,tr|A0A2R8Y4X6|A0A2R8Y4X6_HUMAN,tr|A0A6Q8PFG9|A0A6Q8PFG9_HUMAN,tr|D6RJE6|D6RJE6_HUMAN,tr|A0A6Q8PFN6|A0A6Q8PFN6_HUMAN" 15 1096.5752 1.13 33557 18442 2 1096.583291 549.2949 "Histidine--tRNA ligase, mitochondrial OS=Homo sapiens OX=9606 GN=HARS2 PE=1 SV=1" 4.37 3143.2 - 1.68E+06 - - - 7.372 - 1.93 0.304 - 161.3 1 2 0 0.0081 10 0 0 0 1.40E+07 1.24E+07 - - - 3.1191 0.9921 221125_WJC_METTL3_EV_vs_WT_F03.18443.18443.3 0.0482 Oct-56 K.YYEAADTVTQFDNVR.L "sp|Q8TAQ2|SMRC2_HUMAN,tr|F8VXC8|F8VXC8_HUMAN,tr|F8VZW6|F8VZW6_HUMAN" 3 1790.8111 1.18 33558 18443 3 1790.804868 597.9443 SWI\SNF complex subunit SMARCC2 OS=Homo sapiens OX=9606 GN=SMARCC2 PE=1 SV=1 4.03 3143.3 - 2.29E+06 - - - -3.5046 - 1.772 0.27 - 103.9 1 2 0 -0.0063 15 0 0 0 1.04E+07 8.84E+06 - - - 3.0413 0.9999 221125_WJC_METTL3_EV_vs_WT_F03.18444.18444.2 1.04E-10 14/22 R.SSLDNIEMAYAR.Q "sp|Q8N1F7|NUP93_HUMAN,tr|H3BP95|H3BP95_HUMAN,tr|H3BVG0|H3BVG0_HUMAN,tr|H3BMX0|H3BMX0_HUMAN" 4 1368.6344 35.13 33559 18444 2 1368.634198 685.3245 Nuclear pore complex protein Nup93 OS=Homo sapiens OX=9606 GN=NUP93 PE=1 SV=2 4.37 3143.4 - 1.38E+06 - - - -0.122 - 2.79 0.515 - 594.6 1 2 0 -0.0002 12 0 0 0 2.15E+07 6.11E+05 - - - 5.5444 0.998 221125_WJC_METTL3_EV_vs_WT_F03.18445.18445.3 0.0642 Nov-44 R.GSPHYFSPFR[166.11]PY.- sp|Q13242|SRSF9_HUMAN 1 1463.6862 1.41 33560 18445 3 1463.682878 488.9027 Serine\arginine-rich splicing factor 9 OS=Homo sapiens OX=9606 GN=SRSF9 PE=1 SV=1 8.6 3143.5 - 1.27E+06 - - - -2.2389 - 1.763 0.291 - 186.8 1 2 0 -0.0033 12 0 0 0 1.59E+07 1.12E+07 - - - 3.3551 0.9998 221125_WJC_METTL3_EV_vs_WT_F03.18446.18446.2 6.94E-09 17/26 R.VPTANVSVVDLTC[160.03]R[166.11].L "sp|P04406|G3P_HUMAN,tr|E7EUT5|E7EUT5_HUMAN" 2 1539.7954 1.02 33561 18446 2 1539.794816 770.905 Glyceraldehyde-3-phosphate dehydrogenase OS=Homo sapiens OX=9606 GN=GAPDH PE=1 SV=3 5.8 3143.7 - 801890 - - - -0.4104 - 3.236 0.259 - 1196.4 1 2 0 -0.0006 14 0 0 0 8.36E+09 8.16E+09 - - - 3.9007 1 221125_WJC_METTL3_EV_vs_WT_F03.18447.18447.2 3.73E-11 14/28 K.YYEAADTVTQFDNVR[166.11].L "sp|Q8TAQ2|SMRC2_HUMAN,tr|F8VXC8|F8VXC8_HUMAN,tr|F8VZW6|F8VZW6_HUMAN" 3 1800.8194 3.34 33562 18447 2 1800.818992 901.417 SWI\SNF complex subunit SMARCC2 OS=Homo sapiens OX=9606 GN=SMARCC2 PE=1 SV=1 4.03 3143.8 - 744916 - - - -0.2343 - 3.019 0.686 - 521.2 1 2 0 -0.0004 15 0 0 0 1.83E+07 5.48E+06 - - - 6.8242 0.9927 221125_WJC_METTL3_EV_vs_WT_F03.18449.18449.3 0.276 Dec-48 K.QLSFISPPTPQPK.T sp|O43395|PRPF3_HUMAN 1 1438.782 13.35 33564 18449 3 1438.778645 480.6013 U4\U6 small nuclear ribonucleoprotein Prp3 OS=Homo sapiens OX=9606 GN=PRPF3 PE=1 SV=2 8.75 3144 - 617167 - - - -2.343 - 2.04 0.184 - 197.4 1 2 0 -0.0034 13 0 0 0 7.75E+07 5.80E+06 - - - 2.5235 0.9932 221125_WJC_METTL3_EV_vs_WT_F03.18450.18450.3 0.0731 Nov-40 K.GIHYLATVFEK.K sp|Q86SG5|S1A7A_HUMAN 1 1276.6816 11.66 33565 18450 3 1276.680403 426.5678 Protein S100-A7A OS=Homo sapiens OX=9606 GN=S100A7A PE=1 SV=3 6.75 3144.2 - 573936 - - - -0.9164 - 1.882 0.153 - 224.3 1 2 0 -0.0012 11 0 0 0 6.52E+06 5.60E+05 - - - 2.0418 0.9998 221125_WJC_METTL3_EV_vs_WT_F03.18451.18451.2 2.59E-08 26-Oct R.EWNLPPNAPAC[160.03]MER[166.11].Q sp|Q9BQA1|MEP50_HUMAN 1 1693.758 4.02 33566 18451 2 1693.75555 847.8863 Methylosome protein 50 OS=Homo sapiens OX=9606 GN=WDR77 PE=1 SV=1 4.53 3144.3 - 491985 - - - -1.4559 - 2.281 0.488 - 199.8 1 2 0 -0.0025 14 0 0 0 6.04E+07 1.50E+07 - - - 4.7139 0.9996 221125_WJC_METTL3_EV_vs_WT_F03.18452.18452.3 0.000166 Sep-36 R.C[160.03]NMSLTHFFK.L sp|Q6L8Q7|PDE12_HUMAN 1 1283.5791 0.78 33567 18452 3 1283.576775 428.867 "2',5'-phosphodiesterase 12 OS=Homo sapiens OX=9606 GN=PDE12 PE=1 SV=2" 8.23 3144.4 - 521880 - - - -1.8106 - 1.652 0.399 - 107 1 2 0 -0.0023 10 0 0 0 5.29E+06 6.78E+06 - - - 4.4538 0.9999 221125_WJC_METTL3_EV_vs_WT_F03.18456.18456.2 6.78E-06 24-Nov K.ISSLLEEQFQQGK.L "sp|P62241|RS8_HUMAN,tr|Q5JR95|Q5JR95_HUMAN" 2 1505.7726 0.72 33569 18456 2 1505.772714 753.8936 40S ribosomal protein S8 OS=Homo sapiens OX=9606 GN=RPS8 PE=1 SV=2 4.53 3144.9 - 9.85E+06 - - - 0.0936 - 2.511 0.524 - 364.4 1 2 0 0.0001 13 0 0 0 9.34E+07 1.29E+08 - - - 5.2742 1 221125_WJC_METTL3_EV_vs_WT_F03.18458.18458.3 0.00953 13/44 K.TTISVAHLLAAR.Q "sp|Q8NCA5|FA98A_HUMAN,tr|E9PH82|E9PH82_HUMAN" 2 1251.7299 1.11 33571 18458 3 1251.729209 418.2506 Protein FAM98A OS=Homo sapiens OX=9606 GN=FAM98A PE=1 SV=2 9.44 3145 - 4.97E+06 - - - -0.568 - 2.756 0.461 - 364.7 1 2 0 -0.0007 12 0 0 0 8.64E+07 7.77E+07 - - - 6.4895 1 221125_WJC_METTL3_EV_vs_WT_F03.18459.18459.3 1.31E-05 16/44 K.TTISVAHLLAAR[166.11].Q "sp|Q8NCA5|FA98A_HUMAN,tr|E9PH82|E9PH82_HUMAN" 2 1261.7382 1.11 33572 18459 3 1261.737417 421.5867 Protein FAM98A OS=Homo sapiens OX=9606 GN=FAM98A PE=1 SV=2 9.44 3145 - 4.55E+06 - - - -0.6126 - 2.661 0.436 - 559.4 1 2 0 -0.0008 12 0 0 0 8.64E+07 7.77E+07 - - - 6.1136 0.9996 221125_WJC_METTL3_EV_vs_WT_F03.18460.18460.2 0.0246 20-Oct K.IELLGSYDPQK[136.11].Q sp|P24666|PPAC_HUMAN 1 1269.6696 1.17 33573 18460 2 1269.670689 635.8421 Low molecular weight phosphotyrosine protein phosphatase OS=Homo sapiens OX=9606 GN=ACP1 PE=1 SV=3 4.37 3145 - 4.49E+06 - - - 0.8435 - 1.906 0.357 - 331.4 1 2 0 0.0011 11 0 0 0 1.69E+08 1.44E+08 - - - 3.4224 0.9998 221125_WJC_METTL3_EV_vs_WT_F03.18461.18461.2 4.81E-05 20-Dec K.IELLGSYDPQK.Q sp|P24666|PPAC_HUMAN 1 1261.6554 1.16 33574 18461 2 1261.655469 631.835 Low molecular weight phosphotyrosine protein phosphatase OS=Homo sapiens OX=9606 GN=ACP1 PE=1 SV=3 4.37 3145.1 - 4.23E+06 - - - 0.0404 - 2.296 0.346 - 503.8 1 2 0 0.0001 11 0 0 0 1.69E+08 1.46E+08 - - - 3.845 1 221125_WJC_METTL3_EV_vs_WT_F03.18462.18462.2 8.81E-10 14/26 K.GVVDSDDLPLNVSR[166.11].E "sp|P14625|ENPL_HUMAN,tr|A0A7P0T917|A0A7P0T917_HUMAN,tr|A0A7P0T823|A0A7P0T823_HUMAN,tr|A0A7P0TAE1|A0A7P0TAE1_HUMAN,tr|H0YIV0|H0YIV0_HUMAN,tr|A0A7P0TAY2|A0A7P0TAY2_HUMAN,tr|A0A087WT78|A0A087WT78_HUMAN,tr|A0A7P0TBC2|A0A7P0TBC2_HUMAN,tr|A0A7P0TAT8|A0A7P0TAT8_HUMAN" 9 1494.7554 1.06 33575 18462 2 1494.754219 748.385 Endoplasmin OS=Homo sapiens OX=9606 GN=HSP90B1 PE=1 SV=1 3.93 3145.1 - 3.56E+06 - - - -0.7613 - 3.121 0.635 - 624.8 1 2 0 -0.0011 14 0 0 0 6.97E+07 6.56E+07 - - - 6.5869 0.9998 221125_WJC_METTL3_EV_vs_WT_F03.18463.18463.3 0.00117 13/48 K.ISSLLEEQFQQGK[136.11].L "sp|P62241|RS8_HUMAN,tr|Q5JR95|Q5JR95_HUMAN" 2 1513.7868 0.57 33576 18463 3 1513.78571 505.6029 40S ribosomal protein S8 OS=Homo sapiens OX=9606 GN=RPS8 PE=1 SV=2 4.53 3145.2 - 2.15E+06 - - - -0.7022 - 2.161 0.367 - 195.9 1 2 0 -0.0011 13 0 0 0 1.71E+07 3.01E+07 - - - 4.7206 0.9999 221125_WJC_METTL3_EV_vs_WT_F03.18464.18464.2 0.000113 18-Nov R.DVEDEETWIR.E "sp|Q13813|SPTN1_HUMAN,tr|A0A0D9SF54|A0A0D9SF54_HUMAN,tr|A0A0D9SGF6|A0A0D9SGF6_HUMAN" 3 1290.5728 2.85 33577 18464 2 1290.574225 646.2937 "Spectrin alpha chain, non-erythrocytic 1 OS=Homo sapiens OX=9606 GN=SPTAN1 PE=1 SV=3" 3.83 3145.3 - 2.13E+06 - - - 1.0956 - 2.146 0.558 - 370.8 1 2 0 0.0014 10 0 0 0 3.94E+07 1.39E+07 - - - 5.2934 1 221125_WJC_METTL3_EV_vs_WT_F03.18465.18465.3 1.08E-05 17/52 R.FLFENQTPAHVYYR[166.11].W "sp|O15042|SR140_HUMAN,tr|E7ET15|E7ET15_HUMAN" 2 1793.8765 0.86 33578 18465 3 1793.875807 598.9661 U2 snRNP-associated SURP motif-containing protein OS=Homo sapiens OX=9606 GN=U2SURP PE=1 SV=2 6.75 3145.4 - 1.87E+06 - - - -0.3724 - 2.655 0.486 - 342.5 1 2 0 -0.0007 14 0 0 0 1.57E+07 1.81E+07 - - - 6.5532 0.97 221125_WJC_METTL3_EV_vs_WT_F03.18466.18466.3 0.403 17/36 E.GLKEELAYLR.K "sp|P08779|K1C16_HUMAN,tr|K7ENW6|K7ENW6_HUMAN" 2 1190.6659 63.57 33579 18466 3 1190.663924 397.8959 "Keratin, type I cytoskeletal 16 OS=Homo sapiens OX=9606 GN=KRT16 PE=1 SV=4" 6.14 3145.5 - 1.67E+06 - - - -1.6789 - 2.828 0.401 - 468.9 1 1 1 -0.002 10 0 0 0 1.86E+07 2.93E+05 - - - 6.0462 0.9997 221125_WJC_METTL3_EV_vs_WT_F03.18467.18467.2 0.000524 18-Sep R.DVEDEETWIR[166.11].E "sp|Q13813|SPTN1_HUMAN,tr|A0A0D9SF54|A0A0D9SF54_HUMAN,tr|A0A0D9SGF6|A0A0D9SGF6_HUMAN" 3 1300.5811 2.77 33580 18467 2 1300.580664 651.2978 "Spectrin alpha chain, non-erythrocytic 1 OS=Homo sapiens OX=9606 GN=SPTAN1 PE=1 SV=3" 3.83 3145.6 - 1.40E+06 - - - -0.3206 - 1.847 0.36 - 223.5 1 2 0 -0.0004 10 0 0 0 3.84E+07 1.39E+07 - - - 3.4125 0.9999 221125_WJC_METTL3_EV_vs_WT_F03.18468.18468.2 0.00526 15/30 R.FASEIAGVDDLGTTGR.G "sp|P28331|NDUS1_HUMAN,tr|B4DJ81|B4DJ81_HUMAN" 2 1607.7791 0.73 33581 18468 2 1607.77815 804.8968 "NADH-ubiquinone oxidoreductase 75 kDa subunit, mitochondrial OS=Homo sapiens OX=9606 GN=NDUFS1 PE=1 SV=3" 4.03 3145.7 - 1.25E+06 - - - -0.6002 - 3.051 0.522 - 552.9 1 2 0 -0.001 16 0 0 0 1.69E+07 2.30E+07 - - - 5.6386 1 221125_WJC_METTL3_EV_vs_WT_F03.18469.18469.2 5.15E-05 15/24 R.SLGVTQLAVAVNK[136.11].M "sp|Q9Y450|HBS1L_HUMAN,tr|E9PHZ9|E9PHZ9_HUMAN,tr|H0YDX7|H0YDX7_HUMAN,tr|B7Z524|B7Z524_HUMAN,tr|H0YES5|H0YES5_HUMAN,tr|J3QT46|J3QT46_HUMAN" 6 1306.77 0.48 33582 18469 2 1306.769501 654.3923 HBS1-like protein OS=Homo sapiens OX=9606 GN=HBS1L PE=1 SV=1 8.47 3145.9 - 759674 - - - -0.3826 - 2.919 0.592 - 738 1 2 0 -0.0005 13 0 0 0 7.21E+06 1.51E+07 - - - 6.1627 0.9999 221125_WJC_METTL3_EV_vs_WT_F03.18470.18470.2 2.00E-08 14/28 R.SDSVTPVTVAVITC[160.03]K.Y sp|Q9NZH8|IL36G_HUMAN 1 1575.8178 999 33583 18470 2 1575.818091 788.9162 Interleukin-36 gamma OS=Homo sapiens OX=9606 GN=IL36G PE=1 SV=1 5.55 3146 - 727210 - - - 0.179 - 2.656 0.571 - 505.9 1 2 0 0.0003 15 0 0 0 1.09E+07 0.00E+00 - - - 5.6599 0.9999 221125_WJC_METTL3_EV_vs_WT_F03.18471.18471.2 2.20E-08 24-Dec R.NVEGQDMLYQSLK[136.11].L "sp|P63010|AP2B1_HUMAN,sp|Q10567|AP1B1_HUMAN,tr|A0A087X253|A0A087X253_HUMAN" 3 1531.7432 1.98 33584 18471 2 1531.742277 766.8789 AP-2 complex subunit beta OS=Homo sapiens OX=9606 GN=AP2B1 PE=1 SV=1 4.37 3146.1 - 465764 - - - -0.5987 - 2.333 0.579 - 357 1 2 0 -0.0009 13 0 0 0 1.32E+07 6.67E+06 - - - 5.4915 1 221125_WJC_METTL3_EV_vs_WT_F03.18475.18475.3 5.92E-07 15/52 K.LFPDTPLALDANKK.K sp|Q12906|ILF3_HUMAN 1 1541.8453 0.97 33586 18475 3 1541.843942 514.9557 Interleukin enhancer-binding factor 3 OS=Homo sapiens OX=9606 GN=ILF3 PE=1 SV=3 5.96 3146.6 - 2.53E+06 - - - -0.9093 - 2.61 0.532 - 198.5 1 2 0 -0.0014 14 0 0 0 7.01E+07 7.21E+07 - - - 7.0204 1 221125_WJC_METTL3_EV_vs_WT_F03.18476.18476.3 5.30E-10 16/52 K.LFPDTPLALDANK[136.11]K[136.11].K sp|Q12906|ILF3_HUMAN 1 1557.8737 1.16 33587 18476 3 1557.874171 520.2985 Interleukin enhancer-binding factor 3 OS=Homo sapiens OX=9606 GN=ILF3 PE=1 SV=3 5.96 3146.6 - 2.41E+06 - - - 0.2741 - 3.075 0.581 - 246.8 1 2 0 0.0004 14 0 0 0 1.46E+08 1.26E+08 - - - 8.0027 0.9999 221125_WJC_METTL3_EV_vs_WT_F03.18479.18479.2 2.35E-05 14/22 K.TTISVAHLLAAR.Q "sp|Q8NCA5|FA98A_HUMAN,tr|E9PH82|E9PH82_HUMAN" 2 1251.7299 1.57 33590 18479 2 1251.729498 626.8722 Protein FAM98A OS=Homo sapiens OX=9606 GN=FAM98A PE=1 SV=2 9.44 3146.8 - 1.54E+06 - - - -0.3371 - 2.751 0.499 - 938.6 1 2 0 -0.0004 12 0 0 0 1.84E+07 1.17E+07 - - - 5.3891 1 221125_WJC_METTL3_EV_vs_WT_F03.18481.18481.3 3.58E-06 16/56 K.SSGVPVDGFYTEEVR[166.11].Q "sp|Q9BSD7|NTPCR_HUMAN,tr|Q5TDF0|Q5TDF0_HUMAN" 2 1650.7765 1.18 33592 18481 3 1650.778181 551.2661 Cancer-related nucleoside-triphosphatase OS=Homo sapiens OX=9606 GN=NTPCR PE=1 SV=1 4.14 3147.1 - 1.22E+06 - - - 1.0268 - 2.459 0.509 - 273.9 1 2 0 0.0017 15 0 0 0 4.78E+07 4.05E+07 - - - 6.5622 0.9982 221125_WJC_METTL3_EV_vs_WT_F03.18482.18482.3 0.0304 Oct-52 R.EDISSIEIVGGATR[166.11].L "sp|O95757|HS74L_HUMAN,tr|D6RJ96|D6RJ96_HUMAN,tr|E9PDE8|E9PDE8_HUMAN" 3 1455.7445 0.18 33593 18482 3 1455.740928 486.2554 Heat shock 70 kDa protein 4L OS=Homo sapiens OX=9606 GN=HSPA4L PE=1 SV=3 4.14 3147.1 - 1.17E+06 - - - -2.4249 - 1.686 0.322 - 110.5 1 2 0 -0.0035 14 0 0 0 1.43E+06 7.89E+06 - - - 3.5172 0.9995 221125_WJC_METTL3_EV_vs_WT_F03.18484.18484.3 0.000178 Dec-48 K.NR[166.11]LPPEFSPVIIK[136.11].E "sp|Q9NZB2|F120A_HUMAN,tr|A0A0C4DG79|A0A0C4DG79_HUMAN" 2 1526.894 0.46 33595 18484 3 1526.891599 509.9719 Constitutive coactivator of PPAR-gamma-like protein 1 OS=Homo sapiens OX=9606 GN=FAM120A PE=1 SV=2 8.75 3147.4 - 497148 - - - -1.5522 - 2.312 0.412 - 142.6 1 2 1 -0.0024 13 0 0 0 3.01E+06 6.61E+06 - - - 5.4051 1 221125_WJC_METTL3_EV_vs_WT_F03.18488.18488.2 1.50E-06 18-Dec L.NNQFASFIDK.V "sp|Q8N1N4|K2C78_HUMAN,sp|P04264|K2C1_HUMAN" 2 1182.5669 2.9 33597 18488 2 1182.566229 592.2907 "Keratin, type II cytoskeletal 78 OS=Homo sapiens OX=9606 GN=KRT78 PE=1 SV=2" 5.84 3147.9 - 6.79E+06 - - - -0.5987 - 2.551 0.566 - 850.7 1 1 0 -0.0007 10 0 0 0 8.28E+07 2.86E+07 - - - 5.8353 0.9999 221125_WJC_METTL3_EV_vs_WT_F03.18489.18489.2 2.86E-05 13/22 R.QLFHPEQLITGK[136.11].E "sp|Q9NY65|TBA8_HUMAN,sp|Q6PEY2|TBA3E_HUMAN,sp|P0DPH7|TBA3C_HUMAN,sp|Q71U36|TBA1A_HUMAN,sp|P0DPH8|TBA3D_HUMAN,sp|Q9H853|TBA4B_HUMAN,sp|P68366|TBA4A_HUMAN,sp|P68363|TBA1B_HUMAN,sp|Q9BQE3|TBA1C_HUMAN,tr|C9JJQ8|C9JJQ8_HUMAN,tr|F8VS66|F8VS66_HUMAN,tr|F8VWV9|F8VWV9_HUMAN,tr|F8VRZ4|F8VRZ4_HUMAN,tr|F8VVB9|F8VVB9_HUMAN,tr|C9JQ00|C9JQ00_HUMAN,tr|C9JEV8|C9JEV8_HUMAN,tr|A0A7P0TA31|A0A7P0TA31_HUMAN,tr|A0A1W2PQM2|A0A1W2PQM2_HUMAN,tr|F5H5D3|F5H5D3_HUMAN,tr|C9J2C0|C9J2C0_HUMAN,tr|C9K0S6|C9K0S6_HUMAN,tr|C9JDL2|C9JDL2_HUMAN,tr|F8VQQ4|F8VQQ4_HUMAN,tr|F8VX09|F8VX09_HUMAN,tr|A0A7P0T945|A0A7P0T945_HUMAN" 25 1417.7809 0.49 33598 18489 2 1417.780549 709.8977 Tubulin alpha-8 chain OS=Homo sapiens OX=9606 GN=TUBA8 PE=1 SV=1 6.75 3147.9 - 5.20E+06 - - - -0.2476 - 2.389 0.48 - 666.7 1 2 0 -0.0004 12 0 0 0 5.10E+07 1.05E+08 - - - 4.8776 0.9875 221125_WJC_METTL3_EV_vs_WT_F03.18490.18490.2 4.04E-06 22-Dec R.LLKEYQELMNVK.L "sp|P48668|K2C6C_HUMAN,sp|P04259|K2C6B_HUMAN,sp|P02538|K2C6A_HUMAN" 3 1506.8116 92.75 33599 18490 2 1506.817811 754.4131 "Keratin, type II cytoskeletal 6C OS=Homo sapiens OX=9606 GN=KRT6C PE=1 SV=3" 6.14 3148 - 9.49E+06 - - - 4.1213 - 2.305 0.519 - 347.5 1 2 1 0.0062 12 0 0 0 1.31E+08 1.41E+06 - - - 5.0696 1 221125_WJC_METTL3_EV_vs_WT_F03.18491.18491.3 2.97E-05 17/56 R.K[136.11]FYGPEGPYGVFAGR[166.11].D sp|O00264|PGRC1_HUMAN 1 1661.8321 1.45 33600 18491 3 1661.832145 554.9513 Membrane-associated progesterone receptor component 1 OS=Homo sapiens OX=9606 GN=PGRMC1 PE=1 SV=3 8.5 3148.1 - 1.48E+06 - - - 0.0289 - 2.858 0.456 - 417.5 1 2 0 0 15 0 0 0 8.23E+07 5.69E+07 - - - 6.3641 1 221125_WJC_METTL3_EV_vs_WT_F03.18492.18492.2 3.13E-07 15/26 K.APNYSC[160.03]VMTGSWDK.T "sp|P78406|RAE1L_HUMAN,tr|E9PQ57|E9PQ57_HUMAN,tr|E9PPG9|E9PPG9_HUMAN" 3 1614.6807 0.81 33601 18492 2 1614.66693 808.3476 mRNA export factor OS=Homo sapiens OX=9606 GN=RAE1 PE=1 SV=1 5.87 3148.2 - 1.39E+06 - - - -8.5057 - 3.019 0.666 - 633.7 1 2 0 -0.0137 14 0 0 0 6.48E+06 8.00E+06 - - - 6.7285 0.9996 221125_WJC_METTL3_EV_vs_WT_F03.18493.18493.2 9.35E-06 18-Dec R.WC[160.03]SWSLSQAR.L "sp|P08195|4F2_HUMAN,tr|A0A7P0TAN7|A0A7P0TAN7_HUMAN,tr|J3KPF3|J3KPF3_HUMAN,tr|F5H056|F5H056_HUMAN,tr|F5GZI0|F5GZI0_HUMAN,tr|A0A7P0T8U7|A0A7P0T8U7_HUMAN,tr|A0A7P0T9F7|A0A7P0T9F7_HUMAN,tr|A0A7P0TBF8|A0A7P0TBF8_HUMAN,tr|A0A7P0T8F1|A0A7P0T8F1_HUMAN,tr|H0YFX4|H0YFX4_HUMAN,tr|A0A7P0Z4A0|A0A7P0Z4A0_HUMAN,tr|F5GZS6|F5GZS6_HUMAN,tr|A0A7P0Z4P5|A0A7P0Z4P5_HUMAN,tr|A0A7P0TAS6|A0A7P0TAS6_HUMAN" 14 1279.5768 0.64 33602 18493 2 1279.574137 640.7957 4F2 cell-surface antigen heavy chain OS=Homo sapiens OX=9606 GN=SLC3A2 PE=1 SV=3 8.25 3148.3 - 1.02E+06 - - - -2.0741 - 1.932 0.437 - 449.4 1 2 0 -0.0027 10 0 0 0 8.09E+06 1.26E+07 - - - 4.1061 0.9999 221125_WJC_METTL3_EV_vs_WT_F03.18494.18494.2 1.26E-07 15/28 K.AAYNPGQAVPWNAVK[136.11].V "sp|Q8N163|CCAR2_HUMAN,tr|H0YC69|H0YC69_HUMAN,tr|E5RGU7|E5RGU7_HUMAN,tr|E5RFJ3|E5RFJ3_HUMAN,tr|H0YC58|H0YC58_HUMAN" 5 1592.8191 0.54 33603 18494 2 1592.819845 797.4168 Cell cycle and apoptosis regulator protein 2 OS=Homo sapiens OX=9606 GN=CCAR2 PE=1 SV=2 8.63 3148.4 - 832941 - - - 0.4828 - 2.264 0.508 - 490.5 1 2 0 0.0008 15 0 0 0 8.81E+06 1.62E+07 - - - 4.8018 0.9997 221125_WJC_METTL3_EV_vs_WT_F03.18496.18496.2 4.39E-05 13/24 R.SLGVTQLAVAVNK.M "sp|Q9Y450|HBS1L_HUMAN,tr|E9PHZ9|E9PHZ9_HUMAN,tr|H0YDX7|H0YDX7_HUMAN,tr|B7Z524|B7Z524_HUMAN,tr|H0YES5|H0YES5_HUMAN,tr|J3QT46|J3QT46_HUMAN" 6 1298.7558 0.48 33605 18496 2 1298.757879 650.3852 HBS1-like protein OS=Homo sapiens OX=9606 GN=HBS1L PE=1 SV=1 8.47 3148.7 - 788543 - - - 1.6 - 2.353 0.459 - 542.3 1 2 0 0.0021 13 0 0 0 7.21E+06 1.51E+07 - - - 4.6267 0.9858 221125_WJC_METTL3_EV_vs_WT_F03.18497.18497.2 0.0089 18-Nov L.K[136.11]VPEWVDTVK[136.11].L "sp|P39019|RS19_HUMAN,tr|M0R140|M0R140_HUMAN,tr|M0R2L9|M0R2L9_HUMAN,tr|M0QYF7|M0QYF7_HUMAN" 4 1215.6834 3.51 33606 18497 2 1215.682976 608.849 40S ribosomal protein S19 OS=Homo sapiens OX=9606 GN=RPS19 PE=1 SV=2 6.07 3148.8 - 661289 - - - -0.3685 - 1.976 0.395 - 312.4 1 1 0 -0.0004 10 0 0 0 5.72E+07 1.63E+07 - - - 3.8594 0.999 221125_WJC_METTL3_EV_vs_WT_F03.18498.18498.3 0.000693 Oct-44 R.LLEEK[136.11]DPVPLFK[136.11].L "sp|Q13084|RM28_HUMAN,tr|A2IDC6|A2IDC6_HUMAN" 2 1442.8356 2.59 33607 18498 3 1442.834265 481.9525 "39S ribosomal protein L28, mitochondrial OS=Homo sapiens OX=9606 GN=MRPL28 PE=1 SV=4" 4.68 3148.9 - 656472 - - - -0.9031 - 2.073 0.35 - 130.7 1 2 1 -0.0013 12 0 0 0 2.29E+07 8.83E+06 - - - 4.4625 0.9999 221125_WJC_METTL3_EV_vs_WT_F03.18499.18499.2 1.35E-06 14/30 R.QLVSEEDNTSAPSLFK[136.11].L sp|Q8WTW3|COG1_HUMAN 1 1771.872 1.34 33608 18499 2 1771.869429 886.9433 Conserved oligomeric Golgi complex subunit 1 OS=Homo sapiens OX=9606 GN=COG1 PE=1 SV=1 4.14 3149 - 410145 - - - -1.4284 - 2.618 0.541 - 355.7 1 2 0 -0.0025 16 0 0 0 6.27E+06 4.66E+06 - - - 5.4022 0.9998 221125_WJC_METTL3_EV_vs_WT_F03.18503.18503.2 1.48E-05 20-Nov R.SFMALSQDIQK.T "sp|Q14444|CAPR1_HUMAN,tr|G3V153|G3V153_HUMAN,tr|E9PLA9|E9PLA9_HUMAN" 3 1266.6278 0.76 33610 18503 2 1266.627534 634.3212 Caprin-1 OS=Homo sapiens OX=9606 GN=CAPRIN1 PE=1 SV=2 5.55 3149.4 - 1.16E+07 - - - -0.2282 - 2.296 0.405 - 376.1 1 2 0 -0.0003 11 0 0 0 4.99E+08 6.55E+08 - - - 4.2807 0.9999 221125_WJC_METTL3_EV_vs_WT_F03.18505.18505.3 0.00846 15/44 R.YFEQLLEEEREK.T sp|O15460|P4HA2_HUMAN 1 1611.7781 1.14 33612 18505 3 1611.775982 538.2666 Prolyl 4-hydroxylase subunit alpha-2 OS=Homo sapiens OX=9606 GN=P4HA2 PE=1 SV=1 4.33 3149.6 - 1.46E+06 - - - -1.2849 - 2.412 0.511 - 210.6 1 2 1 -0.0021 12 0 0 0 1.98E+07 1.73E+07 - - - 6.6771 0.9992 221125_WJC_METTL3_EV_vs_WT_F03.18507.18507.2 2.57E-06 14/20 K.TDLDDDITALK[136.11].Q "sp|Q6P1J9|CDC73_HUMAN,tr|A0A2R8YHB3|A0A2R8YHB3_HUMAN,tr|A0A1B0GUB2|A0A1B0GUB2_HUMAN,tr|A0A3B3IRP5|A0A3B3IRP5_HUMAN" 4 1226.6122 1.56 33614 18507 2 1226.607604 614.3134 Parafibromin OS=Homo sapiens OX=9606 GN=CDC73 PE=1 SV=1 3.77 3149.9 - 627343 - - - -3.7167 - 2.589 0.465 - 531.1 1 2 0 -0.0046 11 0 0 0 1.06E+08 6.82E+07 - - - 5.0475 0.9998 221125_WJC_METTL3_EV_vs_WT_F03.18510.18510.2 0.00197 14/22 K.LNDLEDALQQAK.E sp|P04264|K2C1_HUMAN 1 1356.6885 34838.98 33615 18510 2 1356.687897 679.3515 "Keratin, type II cytoskeletal 1 OS=Homo sapiens OX=9606 GN=KRT1 PE=1 SV=6" 4.03 3150.3 - 6.69E+06 - - - -0.4511 - 2.654 0.342 - 792.6 1 2 0 -0.0006 12 0 0 0 1.77E+10 5.09E+05 - - - 4.135 0.9999 221125_WJC_METTL3_EV_vs_WT_F03.18511.18511.2 3.13E-05 20-Dec R.NNYDEEIISLK.N sp|P15924|DESP_HUMAN 1 1336.6511 1.48 33616 18511 2 1336.65109 669.3328 Desmoplakin OS=Homo sapiens OX=9606 GN=DSP PE=1 SV=3 4.14 3150.4 - 2.24E+06 - - - 0.0217 - 2.347 0.509 - 754.6 1 2 0 0 11 0 0 0 6.35E+07 4.30E+07 - - - 5.1084 0.9986 221125_WJC_METTL3_EV_vs_WT_F03.18517.18517.2 2.90E-06 24-Oct K.VVPIASLTPYQSK.W sp|P27694|RFA1_HUMAN 1 1401.7868 1.5 33622 18517 2 1401.780968 701.9007 Replication protein A 70 kDa DNA-binding subunit OS=Homo sapiens OX=9606 GN=RPA1 PE=1 SV=2 8.56 3151 - 1.02E+06 - - - -4.1369 - 1.89 0.535 - 198.1 1 2 0 -0.0058 13 0 0 0 3.20E+07 2.14E+07 - - - 4.6245 0.9998 221125_WJC_METTL3_EV_vs_WT_F03.18518.18518.3 3.33E-05 18/48 R.ILTDYGFEGHPFR.K sp|O75489|NDUS3_HUMAN 1 1550.7518 4.25 33623 18518 3 1550.746895 517.9245 "NADH dehydrogenase [ubiquinone] iron-sulfur protein 3, mitochondrial OS=Homo sapiens OX=9606 GN=NDUFS3 PE=1 SV=1" 5.32 3151.1 - 999847 - - - -3.1488 - 2.792 0.409 - 468.3 1 2 0 -0.0049 13 0 0 0 2.00E+07 4.71E+06 - - - 5.8824 0.8229 221125_WJC_METTL3_EV_vs_WT_F03.18520.18520.3 0.0258 Sep-40 E.TLQEELMALKK.N "sp|P35527|K1C9_HUMAN,tr|K7EQQ3|K7EQQ3_HUMAN" 2 1302.7217 0.03 33625 18520 3 1302.72192 435.2479 "Keratin, type I cytoskeletal 9 OS=Homo sapiens OX=9606 GN=KRT9 PE=1 SV=3" 5.81 3151.4 - 474909 - - - 0.1505 - 1.75 0.241 - 101.4 1 1 0 0.0002 11 0 0 0 5.74E+06 2.12E+08 - - - 2.8166 0.9999 221125_WJC_METTL3_EV_vs_WT_F03.18522.18522.2 0.000985 14/24 K.QLSFISPPTPQPK.T sp|O43395|PRPF3_HUMAN 1 1438.782 2.82 33626 18522 2 1438.780388 720.3983 U4\U6 small nuclear ribonucleoprotein Prp3 OS=Homo sapiens OX=9606 GN=PRPF3 PE=1 SV=2 8.75 3151.6 - 9.70E+06 - - - -1.1315 - 2.566 0.508 - 709.2 1 2 0 -0.0016 13 0 0 0 2.53E+08 8.99E+07 - - - 5.2111 1 221125_WJC_METTL3_EV_vs_WT_F03.18525.18525.3 8.27E-05 13/56 R.LVLEVAQHLGESTVR.T sp|P06576|ATPB_HUMAN 1 1649.9101 1.82 33628 18525 3 1649.906832 550.9773 "ATP synthase subunit beta, mitochondrial OS=Homo sapiens OX=9606 GN=ATP5F1B PE=1 SV=3" 5.4 3151.8 - 6.01E+06 - - - -1.9625 - 2.809 0.49 - 223.6 1 2 0 -0.0032 15 0 0 0 8.08E+08 4.43E+08 - - - 6.6971 0.9999 221125_WJC_METTL3_EV_vs_WT_F03.18526.18526.3 9.63E-06 Dec-56 K.SSGVPVDGFYTEEVR.Q "sp|Q9BSD7|NTPCR_HUMAN,tr|Q5TDF0|Q5TDF0_HUMAN" 2 1640.7682 1.11 33629 18526 3 1640.764116 547.93 Cancer-related nucleoside-triphosphatase OS=Homo sapiens OX=9606 GN=NTPCR PE=1 SV=1 4.14 3151.9 - 4.65E+06 - - - -2.4988 - 2.061 0.531 - 120.2 1 2 0 -0.0041 15 0 0 0 4.82E+07 4.34E+07 - - - 6.3461 1 221125_WJC_METTL3_EV_vs_WT_F03.18527.18527.3 1.30E-07 17/56 R.LVLEVAQHLGESTVR[166.11].T sp|P06576|ATPB_HUMAN 1 1659.9183 1.82 33630 18527 3 1659.916105 554.3134 "ATP synthase subunit beta, mitochondrial OS=Homo sapiens OX=9606 GN=ATP5F1B PE=1 SV=3" 5.4 3151.9 - 4.49E+06 - - - -1.3465 - 3.037 0.537 - 338.5 1 2 0 -0.0022 15 0 0 0 8.08E+08 4.43E+08 - - - 7.4251 0.9997 221125_WJC_METTL3_EV_vs_WT_F03.18528.18528.2 0.81 20-Nov R.SGIDITDFQAK[136.11].R sp|P49790|NU153_HUMAN 1 1201.607 1.36 33631 18528 2 1201.606065 601.8108 Nuclear pore complex protein Nup153 OS=Homo sapiens OX=9606 GN=NUP153 PE=1 SV=2 4.21 3151.9 - 4.08E+06 - - - -0.7931 - 2.226 0.327 - 306.6 1 2 0 -0.001 11 0 0 0 2.08E+08 1.53E+08 - - - 3.6207 0.9996 221125_WJC_METTL3_EV_vs_WT_F03.18529.18529.3 0.00099 13/48 R.K[136.11]FGEAIGMGFPVK[136.11].V "sp|P78347|GTF2I_HUMAN,tr|A0A494C1K3|A0A494C1K3_HUMAN" 2 1395.7555 1.45 33632 18529 3 1395.756332 466.2591 General transcription factor II-I OS=Homo sapiens OX=9606 GN=GTF2I PE=1 SV=2 8.59 3152 - 1.84E+06 - - - 0.5653 - 1.96 0.33 - 261.7 1 2 0 0.0008 13 0 0 0 3.01E+08 2.08E+08 - - - 4.0435 0.9999 221125_WJC_METTL3_EV_vs_WT_F03.18530.18530.3 2.01E-06 16/44 K.LNDLEDALQQAK.E sp|P04264|K2C1_HUMAN 1 1356.6885 129.21 33633 18530 3 1356.687089 453.2368 "Keratin, type II cytoskeletal 1 OS=Homo sapiens OX=9606 GN=KRT1 PE=1 SV=6" 4.03 3152.1 - 1.52E+06 - - - -1.0467 - 2.92 0.342 - 519.6 1 2 0 -0.0014 12 0 0 0 5.53E+08 4.28E+06 - - - 5.3228 0.9999 221125_WJC_METTL3_EV_vs_WT_F03.18533.18533.2 1.13E-05 28-Dec K.EVIPVNVPEAQEEMK[136.11].E "sp|P07814|SYEP_HUMAN,tr|V9GYZ6|V9GYZ6_HUMAN" 2 1718.864 0.68 33636 18533 2 1718.862784 860.4393 Bifunctional glutamate\proline--tRNA ligase OS=Homo sapiens OX=9606 GN=EPRS1 PE=1 SV=5 4.09 3152.5 - 945475 - - - -0.729 - 2.195 0.596 - 347.2 1 2 0 -0.0013 15 0 0 0 9.79E+06 1.45E+07 - - - 5.3755 0.9999 221125_WJC_METTL3_EV_vs_WT_F03.18534.18534.2 0.000172 20-Nov K.VQQTVQDLFGR[166.11].A "sp|P38646|GRP75_HUMAN,tr|A0A7I2V2S7|A0A7I2V2S7_HUMAN,tr|A0A7I2V2G2|A0A7I2V2G2_HUMAN,tr|A0A7I2YQB2|A0A7I2YQB2_HUMAN,tr|D6RCD7|D6RCD7_HUMAN" 5 1299.6811 0.39 33637 18534 2 1299.680168 650.8478 "Stress-70 protein, mitochondrial OS=Homo sapiens OX=9606 GN=HSPA9 PE=1 SV=2" 5.81 3152.6 - 873014 - - - -0.694 - 2.531 0.47 - 666.9 1 2 0 -0.0009 11 0 0 0 9.20E+08 2.37E+09 - - - 5.0243 1 221125_WJC_METTL3_EV_vs_WT_F03.18535.18535.2 1.21E-11 17/28 R.C[160.03]YGFVTMSTAEEATK[136.11].C sp|Q15424|SAFB1_HUMAN 1 1701.747 1.58 33638 18535 2 1701.748358 851.8808 Scaffold attachment factor B1 OS=Homo sapiens OX=9606 GN=SAFB PE=1 SV=4 4.53 3152.8 - 717785 - - - 0.8221 - 2.945 0.695 - 757.6 1 2 0 0.0014 15 0 0 0 1.68E+07 1.06E+07 - - - 6.8293 0.9992 221125_WJC_METTL3_EV_vs_WT_F03.18536.18536.2 0.0149 20-Nov R.IPVINLEDGTR[166.11].L sp|Q9P2D1|CHD7_HUMAN 1 1235.6749 2.76 33639 18536 2 1235.671543 618.8447 Chromodomain-helicase-DNA-binding protein 7 OS=Homo sapiens OX=9606 GN=CHD7 PE=1 SV=3 4.37 3152.9 - 381715 - - - -2.7345 - 2.261 0.36 - 355.9 1 2 0 -0.0034 11 0 0 0 1.39E+07 5.05E+06 - - - 3.9059 0.9998 221125_WJC_METTL3_EV_vs_WT_F03.18539.18539.3 0.000847 Dec-44 K.YQLDKDGVVLFK.K "sp|P07237|PDIA1_HUMAN,tr|A0A7P0TA97|A0A7P0TA97_HUMAN,tr|A0A7P0T8C0|A0A7P0T8C0_HUMAN,tr|H7BZ94|H7BZ94_HUMAN,tr|A0A7P0TA71|A0A7P0TA71_HUMAN,tr|I3L4M2|I3L4M2_HUMAN,tr|A0A7P0T9D6|A0A7P0T9D6_HUMAN,tr|A0A7P0T9K9|A0A7P0T9K9_HUMAN,tr|A0A7P0Z4S2|A0A7P0Z4S2_HUMAN,tr|A0A7P0TA35|A0A7P0TA35_HUMAN,tr|A0A7P0TAX9|A0A7P0TAX9_HUMAN,tr|I3L514|I3L514_HUMAN,tr|A0A7P0TB26|A0A7P0TB26_HUMAN,tr|A0A7P0T9U6|A0A7P0T9U6_HUMAN,tr|I3L0S0|I3L0S0_HUMAN,tr|I3L3P5|I3L3P5_HUMAN,tr|A0A7P0T8J3|A0A7P0T8J3_HUMAN,tr|A0A7P0Z4J0|A0A7P0Z4J0_HUMAN,tr|A0A7P0T8X1|A0A7P0T8X1_HUMAN" 19 1423.7711 1.06 33640 18539 3 1423.768866 475.5976 Protein disulfide-isomerase OS=Homo sapiens OX=9606 GN=P4HB PE=1 SV=3 5.96 3153.3 - 1.02E+07 - - - -1.581 - 2.552 0.502 - 118.3 1 2 1 -0.0023 12 0 0 0 1.95E+08 1.85E+08 - - - 6.7331 1 221125_WJC_METTL3_EV_vs_WT_F03.18540.18540.2 9.95E-07 15/20 K.TDLDDDITALK.Q "sp|Q6P1J9|CDC73_HUMAN,tr|A0A2R8YHB3|A0A2R8YHB3_HUMAN,tr|A0A1B0GUB2|A0A1B0GUB2_HUMAN,tr|A0A3B3IRP5|A0A3B3IRP5_HUMAN" 4 1218.598 1.54 33641 18540 2 1218.595538 610.3063 Parafibromin OS=Homo sapiens OX=9606 GN=CDC73 PE=1 SV=1 3.77 3153.3 - 5.46E+06 - - - -1.99 - 3.021 0.532 - 812.3 1 2 0 -0.0024 11 0 0 0 1.06E+08 6.90E+07 - - - 5.9605 0.9999 221125_WJC_METTL3_EV_vs_WT_F03.18541.18541.2 0.000225 13/24 K.NMLFSGTNIAAGK.A "sp|P16615|AT2A2_HUMAN,sp|O14983|AT2A1_HUMAN,tr|H7C5W9|H7C5W9_HUMAN" 3 1322.6653 1.34 33642 18541 2 1322.664485 662.3399 Sarcoplasmic\endoplasmic reticulum calcium ATPase 2 OS=Homo sapiens OX=9606 GN=ATP2A2 PE=1 SV=1 8.75 3153.4 - 2.03E+06 - - - -0.5943 - 2.469 0.497 - 629.7 1 2 0 -0.0008 13 0 0 0 3.67E+07 2.74E+07 - - - 5.0313 0.9997 221125_WJC_METTL3_EV_vs_WT_F03.18543.18543.2 0.00011 20-Nov K.VQQTVQDLFGR.A "sp|P38646|GRP75_HUMAN,tr|A0A7I2V2S7|A0A7I2V2S7_HUMAN,tr|A0A7I2V2G2|A0A7I2V2G2_HUMAN,tr|A0A7I2YQB2|A0A7I2YQB2_HUMAN,tr|D6RCD7|D6RCD7_HUMAN" 5 1289.6728 0.39 33644 18543 2 1289.674072 645.8437 "Stress-70 protein, mitochondrial OS=Homo sapiens OX=9606 GN=HSPA9 PE=1 SV=2" 5.81 3153.6 - 1.45E+06 - - - 0.9863 - 2.246 0.374 - 550.4 1 2 0 0.0013 11 0 0 0 9.20E+08 2.37E+09 - - - 3.9919 0.9996 221125_WJC_METTL3_EV_vs_WT_F03.18547.18547.2 1.15E-07 26-Nov R.ASLYNAVTIEDVQK[136.11].L sp|Q9Y617|SERC_HUMAN 1 1557.813 1.52 33648 18547 2 1557.808462 779.9138 Phosphoserine aminotransferase OS=Homo sapiens OX=9606 GN=PSAT1 PE=1 SV=2 4.37 3154.1 - 578707 - - - -2.9054 - 2.367 0.593 - 367.4 1 2 0 -0.0045 14 0 0 0 6.83E+06 4.50E+06 - - - 5.5817 0.9981 221125_WJC_METTL3_EV_vs_WT_F03.18548.18548.2 0.575 22-Aug K.LQVGQGVSLTLK[136.11].T "sp|Q14690|RRP5_HUMAN,tr|A0A3B3IUD7|A0A3B3IUD7_HUMAN" 2 1249.7485 1.1 33649 18548 2 1249.748064 625.8815 Protein RRP5 homolog OS=Homo sapiens OX=9606 GN=PDCD11 PE=1 SV=3 8.75 3154.2 - 548817 - - - -0.3785 - 1.617 0.207 - 181 1 2 0 -0.0005 12 0 0 0 2.62E+06 2.37E+06 - - - 1.8342 0.9999 221125_WJC_METTL3_EV_vs_WT_F03.18550.18550.2 0.000622 20-Nov R.SGIDITDFQAK.R sp|P49790|NU153_HUMAN 1 1193.5928 1.36 33650 18550 2 1193.592392 597.8037 Nuclear pore complex protein Nup153 OS=Homo sapiens OX=9606 GN=NUP153 PE=1 SV=2 4.21 3154.4 - 1.30E+07 - - - -0.3569 - 2.506 0.456 - 331.8 1 2 0 -0.0004 11 0 0 0 2.08E+08 1.53E+08 - - - 4.8941 1 221125_WJC_METTL3_EV_vs_WT_F03.18553.18553.2 0.000815 17/28 R.LVLEVAQHLGESTVR[166.11].T sp|P06576|ATPB_HUMAN 1 1659.9183 1.84 33652 18553 2 1659.916126 830.9664 "ATP synthase subunit beta, mitochondrial OS=Homo sapiens OX=9606 GN=ATP5F1B PE=1 SV=3" 5.4 3154.7 - 5.38E+06 - - - -1.3338 - 3.325 0.534 - 1054.5 1 2 0 -0.0022 15 0 0 0 2.42E+08 1.31E+08 - - - 5.9383 0.9999 221125_WJC_METTL3_EV_vs_WT_F03.18556.18556.2 9.46E-06 24-Sep K.EATWTMSNITAGR[166.11].Q "sp|P52292|IMA1_HUMAN,tr|A0A7I2V3Z3|A0A7I2V3Z3_HUMAN,tr|A0A7I2YQE1|A0A7I2YQE1_HUMAN,tr|A0A7I2V487|A0A7I2V487_HUMAN,tr|A0A7I2V351|A0A7I2V351_HUMAN" 5 1446.6801 1.05 33655 18556 2 1446.679007 724.3473 Importin subunit alpha-1 OS=Homo sapiens OX=9606 GN=KPNA2 PE=1 SV=1 6.1 3154.8 - 2.85E+06 - - - -0.7438 - 2.182 0.586 - 225.7 1 2 0 -0.0011 13 0 0 0 7.67E+07 7.32E+07 - - - 5.3714 0.9997 221125_WJC_METTL3_EV_vs_WT_F03.18558.18558.2 0.00563 16-Sep R.AALQELLSK.G sp|P62851|RS25_HUMAN 1 971.5651 1.36 33657 18558 2 971.564948 486.7898 40S ribosomal protein S25 OS=Homo sapiens OX=9606 GN=RPS25 PE=1 SV=1 6.05 3155 - 1.60E+06 - - - -0.2048 - 2.074 0.336 - 196 1 2 0 -0.0002 9 0 0 0 2.69E+07 1.97E+07 - - - 3.6331 1 221125_WJC_METTL3_EV_vs_WT_F03.18560.18560.3 3.90E-06 18/52 R.AALLRPSFIPQEVK.L sp|P0C7T5|ATX1L_HUMAN 1 1567.9086 1.74 33659 18560 3 1567.90599 523.6435 Ataxin-1-like OS=Homo sapiens OX=9606 GN=ATXN1L PE=1 SV=1 8.79 3155.3 - 1.07E+06 - - - -1.6729 - 2.984 0.477 - 428 1 2 0 -0.0026 14 0 0 0 5.64E+07 3.25E+07 - - - 6.7627 1 221125_WJC_METTL3_EV_vs_WT_F03.18561.18561.3 4.79E-06 17/52 K.IC[160.03]GDIHGQYYDLLR[166.11].L "sp|P62136|PP1A_HUMAN,sp|P36873|PP1G_HUMAN,tr|A0A087WYY5|A0A087WYY5_HUMAN,tr|A0A7I2V4F7|A0A7I2V4F7_HUMAN,tr|F8W0W8|F8W0W8_HUMAN,tr|F8VYE8|F8VYE8_HUMAN,tr|F8VR82|F8VR82_HUMAN,tr|E9PMD7|E9PMD7_HUMAN" 8 1731.8278 1.45 33660 18561 3 1731.827996 578.2832 Serine\threonine-protein phosphatase PP1-alpha catalytic subunit OS=Homo sapiens OX=9606 GN=PPP1CA PE=1 SV=1 5.21 3155.4 - 867858 - - - 0.1074 - 2.546 0.512 - 341.7 1 2 0 0.0002 14 0 0 0 2.04E+07 1.40E+07 - - - 6.7318 1 221125_WJC_METTL3_EV_vs_WT_F03.18562.18562.3 4.68E-06 Oct-36 K.EHYLEDILAK.L "sp|Q7L2E3|DHX30_HUMAN,tr|H7BXY3|H7BXY3_HUMAN" 2 1229.6292 0.96 33661 18562 3 1229.62774 410.8837 ATP-dependent RNA helicase DHX30 OS=Homo sapiens OX=9606 GN=DHX30 PE=1 SV=1 4.65 3155.6 - 626196 - - - -1.1898 - 2.189 0.491 - 132.9 1 2 0 -0.0015 10 0 0 0 3.35E+06 3.49E+06 - - - 6.3018 0.9998 221125_WJC_METTL3_EV_vs_WT_F03.18565.18565.2 9.80E-05 24-Oct K.EATWTMSNITAGR.Q "sp|P52292|IMA1_HUMAN,tr|A0A7I2V3Z3|A0A7I2V3Z3_HUMAN,tr|A0A7I2YQE1|A0A7I2YQE1_HUMAN,tr|A0A7I2V487|A0A7I2V487_HUMAN,tr|A0A7I2V351|A0A7I2V351_HUMAN" 5 1436.6718 1.05 33662 18565 2 1436.669083 719.3432 Importin subunit alpha-1 OS=Homo sapiens OX=9606 GN=KPNA2 PE=1 SV=1 6.1 3155.9 - 5.59E+06 - - - -1.9002 - 2.281 0.591 - 315.4 1 2 0 -0.0027 13 0 0 0 7.67E+07 7.32E+07 - - - 5.5217 0.999 221125_WJC_METTL3_EV_vs_WT_F03.18566.18566.2 4.72E-05 20-Nov M.PQYQTWEEFSR.A "sp|P49458|SRP09_HUMAN,tr|Q659G3|Q659G3_HUMAN,tr|E9PE20|E9PE20_HUMAN,tr|Q6P2S0|Q6P2S0_HUMAN" 4 1469.6575 1.28 33663 18566 2 1469.653482 735.836 Signal recognition particle 9 kDa protein OS=Homo sapiens OX=9606 GN=SRP9 PE=1 SV=2 4.53 3156.1 - 2.52E+06 - - - -2.7632 - 1.594 0.456 - 234.4 1 2 0 -0.0041 11 0 0 0 3.22E+08 2.51E+08 - - - 3.669 0.9997 221125_WJC_METTL3_EV_vs_WT_F03.18568.18568.3 0.000441 Nov-52 K.IAILTC[160.03]PFEPPK[136.11]PK[136.11].T "sp|P48643|TCPE_HUMAN,tr|E9PCA1|E9PCA1_HUMAN,tr|B7ZAR1|B7ZAR1_HUMAN,tr|E7ENZ3|E7ENZ3_HUMAN" 4 1625.9186 0.68 33665 18568 3 1625.918358 542.9801 T-complex protein 1 subunit epsilon OS=Homo sapiens OX=9606 GN=CCT5 PE=1 SV=1 8.2 3156.2 - 3.05E+06 - - - -0.1402 - 2.024 0.34 - 127 1 2 0 -0.0002 14 0 0 0 7.22E+07 1.07E+08 - - - 4.2044 0.9999 221125_WJC_METTL3_EV_vs_WT_F03.18570.18570.3 1.99E-06 14/36 R.KMC[160.03]LFAGFQR.K "sp|Q00839|HNRPU_HUMAN,tr|A0A1W2PQL0|A0A1W2PQL0_HUMAN,tr|A0A1W2PPL4|A0A1W2PPL4_HUMAN,tr|A0A1W2PQ74|A0A1W2PQ74_HUMAN,tr|Q5RI18|Q5RI18_HUMAN,tr|A0A1W2PP35|A0A1W2PP35_HUMAN,tr|A0A1W2PPS1|A0A1W2PPS1_HUMAN,tr|A0A1W2PRZ7|A0A1W2PRZ7_HUMAN,tr|A0A1W2PPH7|A0A1W2PPH7_HUMAN,tr|A0A1W2PQD4|A0A1W2PQD4_HUMAN,tr|A0A1W2PP34|A0A1W2PP34_HUMAN,tr|A0A1X7SBS1|A0A1X7SBS1_HUMAN" 12 1256.6158 0.79 33667 18570 3 1256.613211 419.8792 Heterogeneous nuclear ribonucleoprotein U OS=Homo sapiens OX=9606 GN=HNRNPU PE=1 SV=6 9.51 3156.4 - 1.56E+06 - - - -2.0754 - 2.319 0.488 - 220.4 1 2 0 -0.0026 10 0 0 0 2.51E+08 3.16E+08 - - - 6.4365 1 221125_WJC_METTL3_EV_vs_WT_F03.18571.18571.2 2.16E-09 19/24 R.K[136.11]FGEAIGMGFPVK[136.11].V "sp|P78347|GTF2I_HUMAN,tr|A0A494C1K3|A0A494C1K3_HUMAN" 2 1395.7555 1.41 33668 18571 2 1395.763582 698.885 General transcription factor II-I OS=Homo sapiens OX=9606 GN=GTF2I PE=1 SV=2 8.59 3156.5 - 1.34E+06 - - - 5.7596 - 3.589 0.609 - 1011 1 2 0 0.008 13 0 0 0 6.48E+07 4.61E+07 - - - 6.8162 0.9997 221125_WJC_METTL3_EV_vs_WT_F03.18572.18572.2 9.21E-07 14/24 R.VC[160.03]ENIPIVLC[160.03]GNK[136.11].V "sp|P62826|RAN_HUMAN,tr|B5MDF5|B5MDF5_HUMAN,tr|J3KQE5|J3KQE5_HUMAN,tr|B4DV51|B4DV51_HUMAN,tr|F5H018|F5H018_HUMAN" 5 1522.7727 0.93 33669 18572 2 1522.776317 762.3936 GTP-binding nuclear protein Ran OS=Homo sapiens OX=9606 GN=RAN PE=1 SV=3 5.96 3156.6 - 931926 - - - 2.3621 - 2.343 0.54 - 577.8 1 2 0 0.0036 13 0 0 0 4.29E+07 4.61E+07 - - - 5.2135 0.9746 221125_WJC_METTL3_EV_vs_WT_F03.18574.18574.2 0.0111 26-Aug K.GQEDAILSYEPVTR[166.11].Q "sp|Q92796|DLG3_HUMAN,tr|Q5JUW8|Q5JUW8_HUMAN" 2 1586.7816 0.1 33671 18574 2 1586.77366 794.3981 Disks large homolog 3 OS=Homo sapiens OX=9606 GN=DLG3 PE=1 SV=2 4.14 3156.9 - 784550 - - - -4.9862 - 1.469 0.284 - 144.4 1 2 0 -0.0079 14 0 0 0 3.94E+05 3.83E+06 - - - 2.1012 0.9996 221125_WJC_METTL3_EV_vs_WT_F03.18575.18575.2 1.11E-05 18-Nov K.EHYLEDILAK[136.11].L "sp|Q7L2E3|DHX30_HUMAN,tr|H7BXY3|H7BXY3_HUMAN" 2 1237.6434 3.08 33672 18575 2 1237.640324 619.829 ATP-dependent RNA helicase DHX30 OS=Homo sapiens OX=9606 GN=DHX30 PE=1 SV=1 4.65 3157 - 609578 - - - -2.4878 - 2.104 0.489 - 328 1 2 0 -0.0031 10 0 0 0 6.99E+06 2.27E+06 - - - 4.7281 0.9999 221125_WJC_METTL3_EV_vs_WT_F03.18577.18577.3 7.10E-06 13/40 K.LKVPEWVDTVK.L "sp|P39019|RS19_HUMAN,tr|M0R140|M0R140_HUMAN,tr|M0R2L9|M0R2L9_HUMAN,tr|M0QYF7|M0QYF7_HUMAN" 4 1312.7391 1.14 33673 18577 3 1312.737115 438.587 40S ribosomal protein S19 OS=Homo sapiens OX=9606 GN=RPS19 PE=1 SV=2 6.07 3157.2 - 1.13E+08 - - - -1.503 - 2.598 0.536 - 307 1 2 1 -0.002 11 0 0 0 3.26E+09 2.85E+09 - - - 7.2276 0.9994 221125_WJC_METTL3_EV_vs_WT_F03.18578.18578.3 4.51E-05 Sep-40 K.LK[136.11]VPEWVDTVK[136.11].L "sp|P39019|RS19_HUMAN,tr|M0R140|M0R140_HUMAN,tr|M0R2L9|M0R2L9_HUMAN,tr|M0QYF7|M0QYF7_HUMAN" 4 1328.7675 1.14 33674 18578 3 1328.764855 443.9298 40S ribosomal protein S19 OS=Homo sapiens OX=9606 GN=RPS19 PE=1 SV=2 6.07 3157.3 - 1.04E+08 - - - -1.9815 - 2.277 0.41 - 117.6 1 2 1 -0.0026 11 0 0 0 3.26E+09 2.85E+09 - - - 5.448 1 221125_WJC_METTL3_EV_vs_WT_F03.18579.18579.2 2.64E-07 18/28 R.LVLEVAQHLGESTVR.T sp|P06576|ATPB_HUMAN 1 1649.9101 1.84 33675 18579 2 1649.90585 825.9623 "ATP synthase subunit beta, mitochondrial OS=Homo sapiens OX=9606 GN=ATP5F1B PE=1 SV=3" 5.4 3157.3 - 1.89E+07 - - - -2.5577 - 3.125 0.616 - 1318.4 1 2 0 -0.0042 15 0 0 0 2.42E+08 1.31E+08 - - - 6.3908 0.9999 221125_WJC_METTL3_EV_vs_WT_F03.18582.18582.3 1.38E-06 16/52 K.IC[160.03]GDIHGQYYDLLR.L "sp|P62136|PP1A_HUMAN,sp|P36873|PP1G_HUMAN,tr|A0A087WYY5|A0A087WYY5_HUMAN,tr|A0A7I2V4F7|A0A7I2V4F7_HUMAN,tr|F8W0W8|F8W0W8_HUMAN,tr|F8VYE8|F8VYE8_HUMAN,tr|F8VR82|F8VR82_HUMAN,tr|E9PMD7|E9PMD7_HUMAN" 8 1721.8195 1.15 33678 18582 3 1721.815823 574.9471 Serine\threonine-protein phosphatase PP1-alpha catalytic subunit OS=Homo sapiens OX=9606 GN=PPP1CA PE=1 SV=1 5.21 3157.6 - 2.36E+06 - - - -2.1588 - 2.422 0.504 - 214 1 2 0 -0.0037 14 0 0 0 1.50E+07 1.30E+07 - - - 6.5089 0.9001 221125_WJC_METTL3_EV_vs_WT_F03.18583.18583.3 0.756 Nov-40 K.VQQTVQDLFGR[166.11].A "sp|P38646|GRP75_HUMAN,tr|A0A7I2V2S7|A0A7I2V2S7_HUMAN,tr|A0A7I2V2G2|A0A7I2V2G2_HUMAN,tr|A0A7I2YQB2|A0A7I2YQB2_HUMAN,tr|D6RCD7|D6RCD7_HUMAN" 5 1299.6811 0.21 33679 18583 3 1299.675332 434.2343 "Stress-70 protein, mitochondrial OS=Homo sapiens OX=9606 GN=HSPA9 PE=1 SV=2" 5.81 3157.7 - 1.99E+06 - - - -4.4149 - 2.141 0.097 - 251.5 1 2 0 -0.0057 11 0 0 0 1.04E+07 5.07E+07 - - - 1.7825 0.9995 221125_WJC_METTL3_EV_vs_WT_F03.18585.18585.2 0.0577 30-Dec K.LQPQITMIPPSAQPPR.T "sp|P78344|IF4G2_HUMAN,tr|H0Y3P2|H0Y3P2_HUMAN,tr|D3DQV9|D3DQV9_HUMAN" 3 1772.9607 6.46 33681 18585 2 1772.957667 887.4876 Eukaryotic translation initiation factor 4 gamma 2 OS=Homo sapiens OX=9606 GN=EIF4G2 PE=1 SV=1 9.75 3158 - 1.09E+06 - - - -1.7248 - 2.179 0.377 - 185.5 1 2 0 -0.0031 16 0 0 0 2.70E+07 4.18E+06 - - - 3.7394 0.9999 221125_WJC_METTL3_EV_vs_WT_F03.18586.18586.3 0.0003 15/52 K.IC[160.03]GLTLVSAPHLAR[166.11].S "sp|Q13888|TF2H2_HUMAN,sp|Q6P1K8|T2H2L_HUMAN" 2 1516.8423 0.42 33682 18586 3 1516.84146 506.6214 General transcription factor IIH subunit 2 OS=Homo sapiens OX=9606 GN=GTF2H2 PE=1 SV=1 8.26 3158.1 - 1.01E+06 - - - -0.5788 - 2.392 0.369 - 148.8 1 2 0 -0.0009 14 0 0 0 6.70E+06 1.59E+07 - - - 4.9715 0.9998 221125_WJC_METTL3_EV_vs_WT_F03.18589.18589.2 3.24E-06 22-Nov R.EMFGLYGQTTGK.G "sp|Q9Y6B6|SAR1B_HUMAN,tr|D6RD69|D6RD69_HUMAN,tr|D6R9R5|D6R9R5_HUMAN,tr|Q9H029|Q9H029_HUMAN" 4 1330.6227 1.23 33683 18589 2 1330.621281 666.3186 GTP-binding protein SAR1b OS=Homo sapiens OX=9606 GN=SAR1B PE=1 SV=1 6.1 3158.5 - 1.69E+07 - - - -1.095 - 1.712 0.596 - 320 1 2 0 -0.0015 12 0 0 0 2.42E+08 1.98E+08 - - - 4.8573 0.9997 221125_WJC_METTL3_EV_vs_WT_F03.18590.18590.3 0.00401 Dec-36 R.K[136.11]MC[160.03]LFAGFQR[166.11].K "sp|Q00839|HNRPU_HUMAN,tr|A0A1W2PQL0|A0A1W2PQL0_HUMAN,tr|A0A1W2PPL4|A0A1W2PPL4_HUMAN,tr|A0A1W2PQ74|A0A1W2PQ74_HUMAN,tr|Q5RI18|Q5RI18_HUMAN,tr|A0A1W2PP35|A0A1W2PP35_HUMAN,tr|A0A1W2PPS1|A0A1W2PPS1_HUMAN,tr|A0A1W2PRZ7|A0A1W2PRZ7_HUMAN,tr|A0A1W2PPH7|A0A1W2PPH7_HUMAN,tr|A0A1W2PQD4|A0A1W2PQD4_HUMAN,tr|A0A1W2PP34|A0A1W2PP34_HUMAN,tr|A0A1X7SBS1|A0A1X7SBS1_HUMAN" 12 1274.6383 0.79 33684 18590 3 1274.635267 425.8867 Heterogeneous nuclear ribonucleoprotein U OS=Homo sapiens OX=9606 GN=HNRNPU PE=1 SV=6 9.51 3158.5 - 1.32E+07 - - - -2.3709 - 2.134 0.383 - 188.5 1 2 0 -0.003 10 0 0 0 2.51E+08 3.16E+08 - - - 5.0229 0.9998 221125_WJC_METTL3_EV_vs_WT_F03.18591.18591.2 0.00247 20-Nov M.PQYQTWEEFSR[166.11].A "sp|P49458|SRP09_HUMAN,tr|Q659G3|Q659G3_HUMAN,tr|E9PE20|E9PE20_HUMAN,tr|Q6P2S0|Q6P2S0_HUMAN" 4 1479.6658 1.28 33685 18591 2 1479.662812 740.8402 Signal recognition particle 9 kDa protein OS=Homo sapiens OX=9606 GN=SRP9 PE=1 SV=2 4.53 3158.6 - 9.65E+06 - - - -2.0282 - 2.357 0.548 - 426.8 1 2 0 -0.003 11 0 0 0 3.22E+08 2.51E+08 - - - 5.407 1 221125_WJC_METTL3_EV_vs_WT_F03.18592.18592.2 3.39E-08 15/18 R.KMC[160.03]LFAGFQR.K "sp|Q00839|HNRPU_HUMAN,tr|A0A1W2PQL0|A0A1W2PQL0_HUMAN,tr|A0A1W2PPL4|A0A1W2PPL4_HUMAN,tr|A0A1W2PQ74|A0A1W2PQ74_HUMAN,tr|Q5RI18|Q5RI18_HUMAN,tr|A0A1W2PP35|A0A1W2PP35_HUMAN,tr|A0A1W2PPS1|A0A1W2PPS1_HUMAN,tr|A0A1W2PRZ7|A0A1W2PRZ7_HUMAN,tr|A0A1W2PPH7|A0A1W2PPH7_HUMAN,tr|A0A1W2PQD4|A0A1W2PQD4_HUMAN,tr|A0A1W2PP34|A0A1W2PP34_HUMAN,tr|A0A1X7SBS1|A0A1X7SBS1_HUMAN" 12 1256.6158 0.24 33686 18592 2 1256.612887 629.3152 Heterogeneous nuclear ribonucleoprotein U OS=Homo sapiens OX=9606 GN=HNRNPU PE=1 SV=6 9.51 3158.7 - 4.14E+06 - - - -2.3333 - 2.796 0.606 - 907.1 1 2 0 -0.0029 10 0 0 0 1.12E+08 4.60E+08 - - - 6.386 0.9998 221125_WJC_METTL3_EV_vs_WT_F03.18594.18594.2 0.000189 13/24 K.ANPETDPEALFQK.E sp|Q96ES7|SGF29_HUMAN 1 1458.6991 3.11 33688 18594 2 1458.699931 730.3568 SAGA-associated factor 29 OS=Homo sapiens OX=9606 GN=SGF29 PE=1 SV=1 4.14 3158.9 - 2.70E+06 - - - 0.5875 - 2.158 0.483 - 614.4 1 2 0 0.0009 13 0 0 0 7.09E+07 2.28E+07 - - - 4.5823 0.9999 221125_WJC_METTL3_EV_vs_WT_F03.18596.18596.2 4.65E-09 14/22 R.GVDYNAEIPFEK[136.11].K sp|Q99459|CDC5L_HUMAN 1 1388.6703 2.11 33690 18596 2 1388.668921 695.3424 Cell division cycle 5-like protein OS=Homo sapiens OX=9606 GN=CDC5L PE=1 SV=2 4.14 3159.1 - 2.00E+06 - - - -1.0262 - 2.679 0.504 - 557.3 1 2 0 -0.0014 12 0 0 0 1.45E+08 6.90E+07 - - - 5.356 0.9998 221125_WJC_METTL3_EV_vs_WT_F03.18602.18602.3 0.0465 17/40 R.LTFASTLSHLR.R "sp|P30876|RPB2_HUMAN,tr|C9J4M6|C9J4M6_HUMAN,tr|C9J2Y9|C9J2Y9_HUMAN" 3 1244.6877 0.98 33694 18602 3 1244.684065 415.9032 DNA-directed RNA polymerase II subunit RPB2 OS=Homo sapiens OX=9606 GN=POLR2B PE=1 SV=1 9.76 3159.9 - 2.25E+06 - - - -2.9373 - 2.958 0.39 - 454.9 1 2 0 -0.0037 11 0 0 0 2.39E+07 2.43E+07 - - - 5.968 0.9893 221125_WJC_METTL3_EV_vs_WT_F03.18603.18603.2 0.00727 16-Sep R.AALQELLSK[136.11].G sp|P62851|RS25_HUMAN 1 979.5793 1.36 33695 18603 2 979.57481 490.7969 40S ribosomal protein S25 OS=Homo sapiens OX=9606 GN=RPS25 PE=1 SV=1 6.05 3160 - 1.73E+06 - - - -4.6316 - 1.809 0.257 - 201.1 1 2 0 -0.0045 9 0 0 0 2.69E+07 1.97E+07 - - - 2.6527 0.9998 221125_WJC_METTL3_EV_vs_WT_F03.18604.18604.2 0.00124 18-Oct R.GYNFEDLTDR[166.11].N "sp|Q9H7D7|WDR26_HUMAN,tr|A0A7P0SXD0|A0A7P0SXD0_HUMAN,tr|H0Y9R3|H0Y9R3_HUMAN,tr|A0A7I2YQL3|A0A7I2YQL3_HUMAN,tr|A0A7I2YQQ9|A0A7I2YQQ9_HUMAN,tr|A0A499FIZ0|A0A499FIZ0_HUMAN" 6 1238.5443 2.52 33696 18604 2 1238.543129 620.2794 WD repeat-containing protein 26 OS=Homo sapiens OX=9606 GN=WDR26 PE=1 SV=3 4.03 3160.1 - 1.43E+06 - - - -0.9463 - 2.216 0.469 - 400.4 1 2 0 -0.0012 10 0 0 0 5.80E+07 2.30E+07 - - - 4.7257 0.9976 221125_WJC_METTL3_EV_vs_WT_F03.18605.18605.3 0.00126 Sep-40 K.VQQTVQDLFGR.A "sp|P38646|GRP75_HUMAN,tr|A0A7I2V2S7|A0A7I2V2S7_HUMAN,tr|A0A7I2V2G2|A0A7I2V2G2_HUMAN,tr|A0A7I2YQB2|A0A7I2YQB2_HUMAN,tr|D6RCD7|D6RCD7_HUMAN" 5 1289.6728 0.21 33697 18605 3 1289.66812 430.8982 "Stress-70 protein, mitochondrial OS=Homo sapiens OX=9606 GN=HSPA9 PE=1 SV=2" 5.81 3160.3 - 932227 - - - -3.6288 - 1.928 0.322 - 161.5 1 2 0 -0.0047 11 0 0 0 1.04E+07 5.01E+07 - - - 3.9936 0.9999 221125_WJC_METTL3_EV_vs_WT_F03.18609.18609.2 0.00218 13/20 R.EIAQLVEDVQR[166.11].L "sp|Q13948|CASP_HUMAN,sp|P39880|CUX1_HUMAN,tr|A0A2R8Y852|A0A2R8Y852_HUMAN,tr|A0A2R8YDI1|A0A2R8YDI1_HUMAN" 4 1308.6913 10.77 33698 18609 2 1308.690795 655.3529 Protein CASP OS=Homo sapiens OX=9606 GN=CUX1 PE=1 SV=2 4.14 3160.8 - 7.81E+06 - - - -0.3859 - 2.498 0.443 - 834.9 1 2 0 -0.0005 11 0 0 0 1.53E+09 1.42E+08 - - - 4.7895 1 221125_WJC_METTL3_EV_vs_WT_F03.18612.18612.3 9.12E-07 19/52 K.LLDYTEK[136.11]PLYENLR[166.11].D "sp|Q99986|VRK1_HUMAN,tr|A0A7P0T838|A0A7P0T838_HUMAN,tr|H0YJJ9|H0YJJ9_HUMAN,tr|A0A7P0TA16|A0A7P0TA16_HUMAN,tr|A0A7P0T8N0|A0A7P0T8N0_HUMAN,tr|H0YJF7|H0YJF7_HUMAN,tr|A0A7P0T9T1|A0A7P0T9T1_HUMAN,tr|A0A7P0Z445|A0A7P0Z445_HUMAN,tr|A0A7P0TAA6|A0A7P0TAA6_HUMAN,tr|A0A7P0T9E5|A0A7P0T9E5_HUMAN,tr|A0A7P0TBB8|A0A7P0TBB8_HUMAN,tr|A0A7P0Z462|A0A7P0Z462_HUMAN,tr|A0A7P0TBE4|A0A7P0TBE4_HUMAN,tr|A0A7P0T925|A0A7P0T925_HUMAN,tr|H0YJ50|H0YJ50_HUMAN,tr|A0A7P0TA65|A0A7P0TA65_HUMAN,tr|A0A7P0T824|A0A7P0T824_HUMAN,tr|A0A7P0T9I1|A0A7P0T9I1_HUMAN,tr|A0A7P0T977|A0A7P0T977_HUMAN,tr|A0A7P0Z3Z7|A0A7P0Z3Z7_HUMAN,tr|A0A7P0TAS8|A0A7P0TAS8_HUMAN,tr|A0A7P0TB15|A0A7P0TB15_HUMAN,tr|A0A7P0T952|A0A7P0T952_HUMAN" 23 1783.9475 0.38 33701 18612 3 1783.947661 595.6565 Serine\threonine-protein kinase VRK1 OS=Homo sapiens OX=9606 GN=VRK1 PE=1 SV=1 4.68 3161.1 - 2.93E+06 - - - 0.0785 - 3.337 0.541 - 393.3 1 2 0 0.0001 14 0 0 0 1.58E+07 4.16E+07 - - - 7.7741 1 221125_WJC_METTL3_EV_vs_WT_F03.18614.18614.2 1.16E-08 13/26 R.EWNLPPNAPAC[160.03]MER.Q sp|Q9BQA1|MEP50_HUMAN 1 1683.7497 5.74 33703 18614 2 1683.742649 842.8821 Methylosome protein 50 OS=Homo sapiens OX=9606 GN=WDR77 PE=1 SV=1 4.53 3161.4 - 1.82E+06 - - - -4.215 - 2.415 0.645 - 353.6 1 2 0 -0.0071 14 0 0 0 4.78E+07 8.33E+06 - - - 6.0153 0.9699 221125_WJC_METTL3_EV_vs_WT_F03.18616.18616.2 0.000313 Nov-36 K.VVGSAVGSGSITSNIVASN.S "sp|Q9Y5A9|YTHD2_HUMAN,tr|S4R3V3|S4R3V3_HUMAN" 2 1717.8846 - 33705 18616 2 1717.880324 859.9496 YTH domain-containing family protein 2 OS=Homo sapiens OX=9606 GN=YTHDF2 PE=1 SV=2 5.49 3161.7 - 1.18E+06 - - - -2.5141 - 2.225 0.453 - 172.7 1 1 0 -0.0043 19 0 0 0 - - - - - 4.3517 0.9996 221125_WJC_METTL3_EV_vs_WT_F03.18617.18617.3 5.82E-06 18/60 R.ELMLHAADVEALQAAK[136.11].E sp|P12270|TPR_HUMAN 1 1716.896 3.38 33706 18617 3 1716.888992 573.3059 Nucleoprotein TPR OS=Homo sapiens OX=9606 GN=TPR PE=1 SV=3 4.65 3161.8 - 1.14E+06 - - - -4.0853 - 2.861 0.433 - 423.5 1 2 0 -0.007 16 0 0 0 4.54E+07 1.35E+07 - - - 6.0627 0.9987 221125_WJC_METTL3_EV_vs_WT_F03.18618.18618.2 0.00293 28-Dec R.AFVSMVYSEEGAEDR[166.11].T "sp|Q14683|SMC1A_HUMAN,tr|G8JLG1|G8JLG1_HUMAN,tr|A0A6Q8PHC3|A0A6Q8PHC3_HUMAN" 3 1698.7435 1.13 33707 18618 2 1698.742067 850.379 Structural maintenance of chromosomes protein 1A OS=Homo sapiens OX=9606 GN=SMC1A PE=1 SV=2 4 3161.9 - 1.02E+06 - - - -0.8265 - 1.398 0.324 - 68.5 1 2 0 -0.0014 15 0 0 0 1.97E+07 1.75E+07 - - - 2.2573 0.9999 221125_WJC_METTL3_EV_vs_WT_F03.18622.18622.3 0.000307 14/52 K.TAEAQLAYELQGAR.E "sp|Q14254|FLOT2_HUMAN,tr|E7EMK3|E7EMK3_HUMAN,tr|K7EKW9|K7EKW9_HUMAN,tr|J3QLD9|J3QLD9_HUMAN" 4 1519.7631 1.23 33709 18622 3 1519.759814 507.595 Flotillin-2 OS=Homo sapiens OX=9606 GN=FLOT2 PE=1 SV=2 4.53 3162.4 - 3.35E+06 - - - -2.1431 - 2.282 0.461 - 120.6 1 2 0 -0.0033 14 0 0 0 4.07E+07 3.32E+07 - - - 5.8714 0.9992 221125_WJC_METTL3_EV_vs_WT_F03.18625.18625.3 0.00281 Oct-40 R.EIAQLVEDVQR.L "sp|Q13948|CASP_HUMAN,sp|P39880|CUX1_HUMAN,tr|A0A2R8Y852|A0A2R8Y852_HUMAN,tr|A0A2R8YDI1|A0A2R8YDI1_HUMAN" 4 1298.683 2.01 33712 18625 3 1298.680832 433.9016 Protein CASP OS=Homo sapiens OX=9606 GN=CUX1 PE=1 SV=2 4.14 3162.6 - 3.95E+06 - - - -1.6925 - 1.942 0.299 - 228 1 2 0 -0.0022 11 0 0 0 3.74E+07 1.86E+07 - - - 3.7585 1 221125_WJC_METTL3_EV_vs_WT_F03.18626.18626.2 5.62E-07 17/24 K.QSPLNINGASYLR.L "sp|Q6W2J9|BCOR_HUMAN,tr|H7BZ37|H7BZ37_HUMAN,tr|H7C2V9|H7C2V9_HUMAN,tr|A0A5F9ZGX7|A0A5F9ZGX7_HUMAN,tr|H7BYY2|H7BYY2_HUMAN,tr|H7C231|H7C231_HUMAN" 6 1431.747 1.49 33713 18626 2 1431.74744 716.8808 BCL-6 corepressor OS=Homo sapiens OX=9606 GN=BCOR PE=1 SV=1 8.75 3162.7 - 2.78E+06 - - - 0.2885 - 2.779 0.563 - 1148.5 1 2 0 0.0004 13 0 0 0 5.63E+07 3.77E+07 - - - 5.8224 1 221125_WJC_METTL3_EV_vs_WT_F03.18628.18628.2 4.72E-09 21/36 R.ALSSGGSITSPPLSPALPK.Y "sp|Q6Y7W6|GGYF2_HUMAN,tr|F8WCD5|F8WCD5_HUMAN,tr|C9JPV7|C9JPV7_HUMAN,tr|C9JRZ2|C9JRZ2_HUMAN,tr|C9J0V6|C9J0V6_HUMAN,tr|I1E4Y6|I1E4Y6_HUMAN,tr|C9JHT0|C9JHT0_HUMAN,tr|C9JXQ0|C9JXQ0_HUMAN,tr|C9JHW1|C9JHW1_HUMAN,tr|C9JW88|C9JW88_HUMAN,tr|E7ESB6|E7ESB6_HUMAN" 11 1778.9778 3.55 33715 18628 2 1778.969614 890.4962 GRB10-interacting GYF protein 2 OS=Homo sapiens OX=9606 GN=GIGYF2 PE=1 SV=1 8.8 3163 - 1.45E+06 - - - -4.61 - 3.256 0.602 - 948.1 1 2 0 -0.0082 19 0 0 0 2.06E+07 5.82E+06 - - - 6.3871 0.9999 221125_WJC_METTL3_EV_vs_WT_F03.18635.18635.3 0.000125 13/48 K.ELPQFATGENLPR.V "sp|Q9BZZ5|API5_HUMAN,tr|G3V1C3|G3V1C3_HUMAN" 2 1470.7467 4.58 33720 18635 3 1470.746015 491.2562 Apoptosis inhibitor 5 OS=Homo sapiens OX=9606 GN=API5 PE=1 SV=3 4.53 3163.8 - 1.99E+06 - - - -0.461 - 2.306 0.45 - 187.7 1 2 0 -0.0007 13 0 0 0 2.25E+07 4.92E+06 - - - 5.8222 1 221125_WJC_METTL3_EV_vs_WT_F03.18636.18636.2 0.00415 16/28 R.AFVSMVYSEEGAEDR.T "sp|Q14683|SMC1A_HUMAN,tr|G8JLG1|G8JLG1_HUMAN,tr|A0A6Q8PHC3|A0A6Q8PHC3_HUMAN" 3 1688.7352 1.15 33721 18636 2 1688.728793 845.3749 Structural maintenance of chromosomes protein 1A OS=Homo sapiens OX=9606 GN=SMC1A PE=1 SV=2 4 3163.9 - 2.13E+06 - - - -3.7946 - 3.31 0.665 - 897.8 1 2 0 -0.0064 15 0 0 0 1.97E+07 1.72E+07 - - - 6.8934 0.9998 221125_WJC_METTL3_EV_vs_WT_F03.18638.18638.2 0.00125 15/24 K.TILEEEITPTIQK.L "sp|O95347|SMC2_HUMAN,tr|Q5T821|Q5T821_HUMAN" 2 1513.8239 0.96 33723 18638 2 1513.825276 757.9192 Structural maintenance of chromosomes protein 2 OS=Homo sapiens OX=9606 GN=SMC2 PE=1 SV=2 4.25 3164.2 - 2.02E+06 - - - 0.8825 - 2.84 0.391 - 641.9 1 2 0 0.0013 13 0 0 0 1.63E+07 1.70E+07 - - - 4.6075 1 221125_WJC_METTL3_EV_vs_WT_F03.18640.18640.2 3.12E-06 18/34 R.LASTNSSVLGADLPSSMK[136.11].E "sp|Q13428|TCOF_HUMAN,tr|E7ETY2|E7ETY2_HUMAN,tr|H0YA99|H0YA99_HUMAN,tr|H0Y8Y7|H0Y8Y7_HUMAN,tr|A0A3B3IS06|A0A3B3IS06_HUMAN,tr|A0A2R8Y857|A0A2R8Y857_HUMAN" 6 1784.907 1.24 33725 18640 2 1784.899852 893.4608 Treacle protein OS=Homo sapiens OX=9606 GN=TCOF1 PE=1 SV=3 5.84 3164.4 - 1.43E+06 - - - -3.9851 - 3.633 0.569 - 807.9 1 2 0 -0.0071 18 0 0 0 1.71E+07 1.38E+07 - - - 6.4131 0.9999 221125_WJC_METTL3_EV_vs_WT_F03.18641.18641.3 6.32E-05 16/56 R.GFLSAPVFAGTHSGR.A sp|P35453|HXD13_HUMAN 1 1502.763 2.06 33726 18641 3 1502.758781 501.9283 Homeobox protein Hox-D13 OS=Homo sapiens OX=9606 GN=HOXD13 PE=1 SV=3 9.76 3164.5 - 1.26E+06 - - - -2.8155 - 2.377 0.483 - 210 1 2 0 -0.0042 15 0 0 0 1.50E+07 7.29E+06 - - - 6.1831 0.9999 221125_WJC_METTL3_EV_vs_WT_F03.18645.18645.3 0.059 Nov-48 R.RIGFDVVTLSGTR.G "sp|Q9BSD7|NTPCR_HUMAN,tr|Q5TDF0|Q5TDF0_HUMAN" 2 1419.7834 0.95 33728 18645 3 1419.781845 474.2684 Cancer-related nucleoside-triphosphatase OS=Homo sapiens OX=9606 GN=NTPCR PE=1 SV=1 9.6 3165 - 3.34E+06 - - - -1.1044 - 2.559 0.41 - 144.8 1 2 0 -0.0016 13 0 0 0 9.22E+07 9.71E+07 - - - 5.6582 0.9999 221125_WJC_METTL3_EV_vs_WT_F03.18646.18646.3 0.027 18/60 K.LQPQITMIPPSAQPPR.T "sp|P78344|IF4G2_HUMAN,tr|H0Y3P2|H0Y3P2_HUMAN,tr|D3DQV9|D3DQV9_HUMAN" 3 1772.9607 1.45 33729 18646 3 1772.9597 591.9942 Eukaryotic translation initiation factor 4 gamma 2 OS=Homo sapiens OX=9606 GN=EIF4G2 PE=1 SV=1 9.75 3165.1 - 2.06E+06 - - - -0.5781 - 2.823 0.406 - 384.5 1 2 0 -0.001 16 0 0 0 5.57E+07 3.84E+07 - - - 5.7291 1 221125_WJC_METTL3_EV_vs_WT_F03.18649.18649.3 0.00602 15/48 R.IIDSLFNTVTDK[136.11]K[136.11].L sp|O60701|UGDH_HUMAN 1 1508.8421 2.32 33732 18649 3 1508.842777 503.9546 UDP-glucose 6-dehydrogenase OS=Homo sapiens OX=9606 GN=UGDH PE=1 SV=1 5.96 3165.4 - 1.36E+06 - - - 0.4421 - 2.842 0.502 - 284.2 1 2 0 0.0007 13 0 0 0 2.39E+07 1.03E+07 - - - 6.9686 0.9999 221125_WJC_METTL3_EV_vs_WT_F03.18650.18650.2 8.47E-05 14/20 K.WEGLVYAPPGK.E "sp|Q9Y2W1|TR150_HUMAN,tr|A0A3B3ITZ9|A0A3B3ITZ9_HUMAN" 2 1215.6288 2.59 33733 18650 2 1215.628142 608.8217 Thyroid hormone receptor-associated protein 3 OS=Homo sapiens OX=9606 GN=THRAP3 PE=1 SV=2 6 3165.6 - 1.34E+06 - - - -0.5487 - 2.551 0.528 - 497.6 1 2 0 -0.0007 11 0 0 0 2.46E+08 9.50E+07 - - - 5.474 1 221125_WJC_METTL3_EV_vs_WT_F03.18651.18651.3 0.000827 18/48 R.IIDSLFNTVTDKK.L sp|O60701|UGDH_HUMAN 1 1492.8137 2.19 33734 18651 3 1492.814188 498.6118 UDP-glucose 6-dehydrogenase OS=Homo sapiens OX=9606 GN=UGDH PE=1 SV=1 5.96 3165.6 - 1.24E+06 - - - 0.3202 - 3.214 0.445 - 444.3 1 2 0 0.0005 13 0 0 0 2.26E+07 1.03E+07 - - - 6.6667 1 221125_WJC_METTL3_EV_vs_WT_F03.18652.18652.2 4.65E-10 16/32 K.GPDGLTAFEATDNQAIK.A "sp|P58546|MTPN_HUMAN,tr|C9JL85|C9JL85_HUMAN" 2 1746.8424 -1 33735 18652 2 1746.82666 874.4285 Myotrophin OS=Homo sapiens OX=9606 GN=MTPN PE=1 SV=2 4.03 3165.8 - 875771 - - - -9.0357 - 2.978 0.655 - 527.6 1 2 0 -0.0158 17 0 0 0 0.00E+00 0.00E+00 - - - 6.5568 0.9972 221125_WJC_METTL3_EV_vs_WT_F03.18653.18653.2 0.00859 18-Sep K.QGIQFYTQLK[136.11].T "sp|Q02252|MMSA_HUMAN,tr|G3V4Z4|G3V4Z4_HUMAN" 2 1232.6645 3.52 33736 18653 2 1232.667551 617.3395 "Methylmalonate-semialdehyde dehydrogenase [acylating], mitochondrial OS=Homo sapiens OX=9606 GN=ALDH6A1 PE=1 SV=2" 8.59 3165.9 - 837532 - - - 2.497 - 1.683 0.272 - 210 1 2 0 0.0031 10 0 0 0 1.27E+07 3.60E+06 - - - 2.5021 0.9997 221125_WJC_METTL3_EV_vs_WT_F03.18655.18655.2 0.00014 Oct-32 R.MAPYQGPDAVPGALDYK.S "sp|O43707|ACTN4_HUMAN,tr|F5GXS2|F5GXS2_HUMAN,tr|H7C144|H7C144_HUMAN" 3 1791.8502 0.68 33738 18655 2 1791.851182 896.9324 Alpha-actinin-4 OS=Homo sapiens OX=9606 GN=ACTN4 PE=1 SV=2 4.21 3166.2 - 579323 - - - 0.5637 - 1.837 0.424 - 137.6 1 2 0 0.001 17 0 0 0 6.36E+06 9.33E+06 - - - 3.6675 0.9998 221125_WJC_METTL3_EV_vs_WT_F03.18658.18658.2 1.71E-05 Nov-32 R.MAPYQGPDAVPGALDYK[136.11].S "sp|O43707|ACTN4_HUMAN,tr|F5GXS2|F5GXS2_HUMAN,tr|H7C144|H7C144_HUMAN" 3 1799.8644 1.47 33741 18658 2 1799.866461 900.9395 Alpha-actinin-4 OS=Homo sapiens OX=9606 GN=ACTN4 PE=1 SV=2 4.21 3166.6 - 523355 - - - 1.1606 - 2.175 0.481 - 187.3 1 2 0 0.0021 17 0 0 0 5.65E+06 3.84E+06 - - - 4.5034 1 221125_WJC_METTL3_EV_vs_WT_F03.18659.18659.2 7.75E-08 14/32 K.GPDGLTAFEATDNQAIK[136.11].A "sp|P58546|MTPN_HUMAN,tr|C9JL85|C9JL85_HUMAN" 2 1754.8566 0.29 33742 18659 2 1754.855542 878.4356 Myotrophin OS=Homo sapiens OX=9606 GN=MTPN PE=1 SV=2 4.03 3166.7 - 504326 - - - -0.628 - 2.965 0.63 - 429 1 2 0 -0.0011 17 0 0 0 2.59E+06 9.01E+06 - - - 6.366 1 221125_WJC_METTL3_EV_vs_WT_F03.18661.18661.3 5.84E-07 13/48 R.KFGEAIGMGFPVK.V "sp|P78347|GTF2I_HUMAN,tr|A0A494C1K3|A0A494C1K3_HUMAN" 2 1379.7271 1.45 33743 18661 3 1379.725847 460.9163 General transcription factor II-I OS=Homo sapiens OX=9606 GN=GTF2I PE=1 SV=2 8.59 3166.9 - 9.16E+06 - - - -0.9393 - 2.498 0.502 - 280.6 1 2 0 -0.0013 13 0 0 0 3.03E+08 2.09E+08 - - - 6.6186 0.9999 221125_WJC_METTL3_EV_vs_WT_F03.18662.18662.2 1.05E-06 20-Sep R.TTAENEFVMLK.K "sp|P13647|K2C5_HUMAN,tr|F8W0C6|F8W0C6_HUMAN,tr|H0YIN9|H0YIN9_HUMAN" 3 1281.6275 999 33744 18662 2 1281.62816 641.821 "Keratin, type II cytoskeletal 5 OS=Homo sapiens OX=9606 GN=KRT5 PE=1 SV=3" 4.53 3167 - 1.42E+06 - - - 0.5236 - 2.228 0.515 - 295.9 1 2 0 0.0007 11 0 0 0 2.19E+08 0.00E+00 - - - 5.0118 0.9999 221125_WJC_METTL3_EV_vs_WT_F03.18663.18663.2 7.39E-05 24-Nov K.ELPQFATGENLPR.V "sp|Q9BZZ5|API5_HUMAN,tr|G3V1C3|G3V1C3_HUMAN" 2 1470.7467 1.44 33745 18663 2 1470.747498 736.3806 Apoptosis inhibitor 5 OS=Homo sapiens OX=9606 GN=API5 PE=1 SV=3 4.53 3167.1 - 7.28E+06 - - - 0.5473 - 2.227 0.535 - 286.5 1 2 0 0.0008 13 0 0 0 8.45E+07 5.88E+07 - - - 5.0472 0.9997 221125_WJC_METTL3_EV_vs_WT_F03.18664.18664.2 0.0392 18-Oct R.TFSWASVTSK.N "sp|Q13283|G3BP1_HUMAN,tr|A0A7I2V5M7|A0A7I2V5M7_HUMAN,tr|A0A7I2YQM1|A0A7I2YQM1_HUMAN,tr|A0A7P0P2U7|A0A7P0P2U7_HUMAN,tr|A0A7I2YQU8|A0A7I2YQU8_HUMAN,tr|A0A7I2V651|A0A7I2V651_HUMAN,tr|A0A7I2V4D8|A0A7I2V4D8_HUMAN,tr|A0A7I2YQN9|A0A7I2YQN9_HUMAN" 8 1112.5502 0.97 33746 18664 2 1112.551068 557.2824 Ras GTPase-activating protein-binding protein 1 OS=Homo sapiens OX=9606 GN=G3BP1 PE=1 SV=1 8.41 3167.1 - 5.51E+06 - - - 0.7577 - 1.69 0.421 - 240.2 1 2 0 0.0008 10 0 0 0 2.16E+08 2.23E+08 - - - 3.6149 1 221125_WJC_METTL3_EV_vs_WT_F03.18665.18665.2 8.49E-10 13/24 K.LTFDTTFSPNTGK.K "sp|P45880|VDAC2_HUMAN,tr|Q5JSD1|Q5JSD1_HUMAN,tr|Q5JSD2|Q5JSD2_HUMAN,tr|A0A0A0MR02|A0A0A0MR02_HUMAN" 4 1427.6933 1.22 33747 18665 2 1427.694125 714.8539 Voltage-dependent anion-selective channel protein 2 OS=Homo sapiens OX=9606 GN=VDAC2 PE=1 SV=2 5.84 3167.2 - 4.87E+06 - - - 0.6059 - 2.499 0.647 - 566.5 1 2 0 0.0009 13 0 0 0 5.26E+07 4.30E+07 - - - 6.1701 1 221125_WJC_METTL3_EV_vs_WT_F03.18667.18667.2 5.80E-12 18/28 R.NPDDITQEEYGEFYK[136.11].S sp|P08238|HS90B_HUMAN 1 1854.8039 0.95 33749 18667 2 1854.804068 928.4092 Heat shock protein HSP 90-beta OS=Homo sapiens OX=9606 GN=HSP90AB1 PE=1 SV=4 3.83 3167.4 - 2.85E+06 - - - 0.069 - 3.357 0.687 - 1233.9 1 2 0 0.0001 15 0 0 0 7.12E+07 7.53E+07 - - - 7.0926 1 221125_WJC_METTL3_EV_vs_WT_F03.18668.18668.2 4.04E-06 24-Dec K.EQLDNQLDAYMSK.T "sp|Q9Y3Y2|CHTOP_HUMAN,tr|X6R700|X6R700_HUMAN" 2 1553.7032 4.64 33750 18668 2 1553.702634 777.8589 Chromatin target of PRMT1 protein OS=Homo sapiens OX=9606 GN=CHTOP PE=1 SV=2 4.03 3167.4 - 2.74E+06 - - - -0.3469 - 2.657 0.577 - 538 1 2 0 -0.0005 13 0 0 0 7.13E+07 1.54E+07 - - - 5.8106 1 221125_WJC_METTL3_EV_vs_WT_F03.18669.18669.3 2.51E-05 Dec-36 K.DYAFVHFEDR.G "sp|O43390|HNRPR_HUMAN,tr|B4DT28|B4DT28_HUMAN,tr|A0A6Q8PH31|A0A6Q8PH31_HUMAN,tr|A0A6Q8PH35|A0A6Q8PH35_HUMAN,tr|A0A286YEZ8|A0A286YEZ8_HUMAN" 5 1297.5728 1.38 33751 18669 3 1297.573087 433.5315 Heterogeneous nuclear ribonucleoprotein R OS=Homo sapiens OX=9606 GN=HNRNPR PE=1 SV=1 4.54 3167.5 - 2.23E+06 - - - 0.2589 - 2.246 0.529 - 259 1 2 0 0.0003 10 0 0 0 2.05E+07 1.48E+07 - - - 6.8008 0.9996 221125_WJC_METTL3_EV_vs_WT_F03.18670.18670.2 7.26E-05 18-Oct R.SWLSYSYQSR.F sp|Q15393|SF3B3_HUMAN 1 1275.5884 1.14 33752 18670 2 1275.588336 638.8015 Splicing factor 3B subunit 3 OS=Homo sapiens OX=9606 GN=SF3B3 PE=1 SV=4 8.31 3167.6 - 2.10E+06 - - - -0.051 - 2.042 0.289 - 412.6 1 2 0 -0.0001 10 0 0 0 2.25E+07 1.97E+07 - - - 3.1683 0.9999 221125_WJC_METTL3_EV_vs_WT_F03.18673.18673.3 0.000448 Oct-36 K.DYAFVHFEDR[166.11].G "sp|O43390|HNRPR_HUMAN,tr|B4DT28|B4DT28_HUMAN,tr|A0A6Q8PH31|A0A6Q8PH31_HUMAN,tr|A0A6Q8PH35|A0A6Q8PH35_HUMAN,tr|A0A286YEZ8|A0A286YEZ8_HUMAN" 5 1307.581 1.37 33755 18673 3 1307.580733 436.8676 Heterogeneous nuclear ribonucleoprotein R OS=Homo sapiens OX=9606 GN=HNRNPR PE=1 SV=1 4.54 3167.8 - 1.82E+06 - - - -0.2203 - 2.234 0.384 - 173.4 1 2 0 -0.0003 10 0 0 0 2.04E+07 1.48E+07 - - - 5.1686 0.9999 221125_WJC_METTL3_EV_vs_WT_F03.18674.18674.2 3.36E-05 13/22 R.C[160.03]NEPAVWSQLAK[136.11].A "sp|Q00610|CLH1_HUMAN,tr|A0A087WVQ6|A0A087WVQ6_HUMAN" 2 1409.6853 0.61 33756 18674 2 1409.686046 705.8499 Clathrin heavy chain 1 OS=Homo sapiens OX=9606 GN=CLTC PE=1 SV=5 5.99 3167.9 - 1.75E+06 - - - 0.5398 - 2.541 0.552 - 592.9 1 2 0 0.0008 12 0 0 0 1.21E+07 1.98E+07 - - - 5.5716 1 221125_WJC_METTL3_EV_vs_WT_F03.18675.18675.2 3.85E-07 13/22 R.C[160.03]NEPAVWSQLAK.A "sp|Q00610|CLH1_HUMAN,tr|A0A087WVQ6|A0A087WVQ6_HUMAN" 2 1401.6711 0.61 33757 18675 2 1401.667457 701.8428 Clathrin heavy chain 1 OS=Homo sapiens OX=9606 GN=CLTC PE=1 SV=5 5.99 3168 - 1.52E+06 - - - -2.5883 - 2.472 0.588 - 664.8 1 2 0 -0.0036 12 0 0 0 1.21E+07 1.98E+07 - - - 5.7641 1 221125_WJC_METTL3_EV_vs_WT_F03.18676.18676.2 6.74E-08 14/24 K.TILEEEITPTIQK[136.11].L "sp|O95347|SMC2_HUMAN,tr|Q5T821|Q5T821_HUMAN" 2 1521.8381 0.95 33758 18676 2 1521.840909 761.9263 Structural maintenance of chromosomes protein 2 OS=Homo sapiens OX=9606 GN=SMC2 PE=1 SV=2 4.25 3168.1 - 1.49E+06 - - - 1.8195 - 2.898 0.572 - 518.6 1 2 0 0.0028 13 0 0 0 1.65E+07 1.73E+07 - - - 5.9958 1 221125_WJC_METTL3_EV_vs_WT_F03.18677.18677.3 1.57E-05 14/44 R.LAVLSSSLTHWK[136.11].K "sp|Q6IAA8|LTOR1_HUMAN,tr|F5GX19|F5GX19_HUMAN,tr|F5H3Y3|F5H3Y3_HUMAN" 3 1348.7594 0.28 33759 18677 3 1348.761386 450.5938 Ragulator complex protein LAMTOR1 OS=Homo sapiens OX=9606 GN=LAMTOR1 PE=1 SV=2 8.76 3168.2 - 1.46E+06 - - - 1.4458 - 2.721 0.473 - 348.4 1 2 0 0.0019 12 0 0 0 6.80E+06 2.39E+07 - - - 6.5876 1 221125_WJC_METTL3_EV_vs_WT_F03.18678.18678.3 0.000472 16/44 R.LAVLSSSLTHWK.K "sp|Q6IAA8|LTOR1_HUMAN,tr|F5GX19|F5GX19_HUMAN,tr|F5H3Y3|F5H3Y3_HUMAN" 3 1340.7452 0.31 33760 18678 3 1340.745819 447.9224 Ragulator complex protein LAMTOR1 OS=Homo sapiens OX=9606 GN=LAMTOR1 PE=1 SV=2 8.76 3168.3 - 1.36E+06 - - - 0.4348 - 3.173 0.416 - 525.2 1 2 0 0.0006 12 0 0 0 6.50E+06 2.09E+07 - - - 6.3784 0.9997 221125_WJC_METTL3_EV_vs_WT_F03.18679.18679.2 0.00883 18-Oct R.NLPVNFEVAR.E "sp|O95793|STAU1_HUMAN,tr|Q5JW30|Q5JW30_HUMAN" 2 1157.6193 2.43 33761 18679 2 1157.618925 579.8169 Double-stranded RNA-binding protein Staufen homolog 1 OS=Homo sapiens OX=9606 GN=STAU1 PE=1 SV=2 6 3168.4 - 1.22E+06 - - - -0.33 - 1.825 0.378 - 338.2 1 2 0 -0.0004 10 0 0 0 9.48E+06 3.90E+06 - - - 3.512 1 221125_WJC_METTL3_EV_vs_WT_F03.18680.18680.2 8.09E-10 16/28 K.SSEPVVTMSVEYQMK.S sp|P18583|SON_HUMAN 1 1713.7954 0.79 33762 18680 2 1713.798183 857.905 Protein SON OS=Homo sapiens OX=9606 GN=SON PE=1 SV=4 4.53 3168.6 - 1.04E+06 - - - 1.6478 - 2.897 0.604 - 840.6 1 2 0 0.0028 15 0 0 0 1.00E+07 1.27E+07 - - - 6.1164 1 221125_WJC_METTL3_EV_vs_WT_F03.18683.18683.2 3.39E-10 18/36 R.ALSSGGSITSPPLSPALPK[136.11].Y "sp|Q6Y7W6|GGYF2_HUMAN,tr|F8WCD5|F8WCD5_HUMAN,tr|C9JPV7|C9JPV7_HUMAN,tr|C9JRZ2|C9JRZ2_HUMAN,tr|C9J0V6|C9J0V6_HUMAN,tr|I1E4Y6|I1E4Y6_HUMAN,tr|C9JHT0|C9JHT0_HUMAN,tr|C9JXQ0|C9JXQ0_HUMAN,tr|C9JHW1|C9JHW1_HUMAN,tr|C9JW88|C9JW88_HUMAN,tr|E7ESB6|E7ESB6_HUMAN" 11 1786.992 3.45 33764 18683 2 1786.992828 894.5033 GRB10-interacting GYF protein 2 OS=Homo sapiens OX=9606 GN=GIGYF2 PE=1 SV=1 8.8 3168.9 - 968714 - - - 0.455 - 3.276 0.621 - 656 1 2 0 0.0008 19 0 0 0 2.51E+07 7.28E+06 - - - 6.5448 0.9999 221125_WJC_METTL3_EV_vs_WT_F03.18684.18684.2 1.42E-05 18-Nov R.TFSWASVTSK[136.11].N "sp|Q13283|G3BP1_HUMAN,tr|A0A7I2V5M7|A0A7I2V5M7_HUMAN,tr|A0A7I2YQM1|A0A7I2YQM1_HUMAN,tr|A0A7P0P2U7|A0A7P0P2U7_HUMAN,tr|A0A7I2YQU8|A0A7I2YQU8_HUMAN,tr|A0A7I2V651|A0A7I2V651_HUMAN,tr|A0A7I2V4D8|A0A7I2V4D8_HUMAN,tr|A0A7I2YQN9|A0A7I2YQN9_HUMAN" 8 1120.5644 0.97 33765 18684 2 1120.565081 561.2895 Ras GTPase-activating protein-binding protein 1 OS=Homo sapiens OX=9606 GN=G3BP1 PE=1 SV=1 8.41 3169 - 1.85E+07 - - - 0.5854 - 1.905 0.531 - 316.3 1 2 0 0.0007 10 0 0 0 2.18E+08 2.24E+08 - - - 4.7617 0.9999 221125_WJC_METTL3_EV_vs_WT_F03.18685.18685.3 0.00675 Dec-48 R.NILSVVGTDALKK.T sp|O43172|PRP4_HUMAN 1 1356.7977 2.85 33766 18685 3 1356.79793 453.2732 U4\U6 small nuclear ribonucleoprotein Prp4 OS=Homo sapiens OX=9606 GN=PRPF4 PE=1 SV=2 8.59 3169 - 7.26E+06 - - - 0.1946 - 2.839 0.399 - 155.2 1 2 0 0.0003 13 0 0 0 1.65E+08 5.81E+07 - - - 5.8175 0.9999 221125_WJC_METTL3_EV_vs_WT_F03.18686.18686.2 2.94E-06 20-Dec K.WEGLVYAPPGK[136.11].E "sp|Q9Y2W1|TR150_HUMAN,tr|A0A3B3ITZ9|A0A3B3ITZ9_HUMAN" 2 1223.643 2.74 33767 18686 2 1223.644013 612.8288 Thyroid hormone receptor-associated protein 3 OS=Homo sapiens OX=9606 GN=THRAP3 PE=1 SV=2 6 3169 - 5.07E+06 - - - 0.8205 - 2.232 0.568 - 388.5 1 2 0 0.001 11 0 0 0 2.67E+08 9.73E+07 - - - 5.408 0.9999 221125_WJC_METTL3_EV_vs_WT_F03.18687.18687.3 2.40E-06 Nov-52 K.THLPGFVEQAEALK.A sp|P30044|PRDX5_HUMAN 1 1538.8093 1.42 33768 18687 3 1538.811076 513.9437 "Peroxiredoxin-5, mitochondrial OS=Homo sapiens OX=9606 GN=PRDX5 PE=1 SV=4" 5.37 3169.1 - 3.89E+06 - - - 1.1587 - 2.415 0.426 - 188 1 2 0 0.0018 14 0 0 0 5.06E+07 3.56E+07 - - - 5.6321 1 221125_WJC_METTL3_EV_vs_WT_F03.18688.18688.3 5.23E-06 16/48 R.NILSVVGTDALK[136.11]K[136.11].T sp|O43172|PRP4_HUMAN 1 1372.8261 2.87 33769 18688 3 1372.826245 458.616 U4\U6 small nuclear ribonucleoprotein Prp4 OS=Homo sapiens OX=9606 GN=PRPF4 PE=1 SV=2 8.59 3169.1 - 3.53E+06 - - - 0.1304 - 2.532 0.462 - 249.7 1 2 0 0.0002 13 0 0 0 1.65E+08 5.76E+07 - - - 6.2096 0.9999 221125_WJC_METTL3_EV_vs_WT_F03.18689.18689.2 2.34E-05 18-Aug R.GDEELDSLIK[136.11].A "sp|P0C0S5|H2AZ_HUMAN,sp|Q71UI9|H2AV_HUMAN,tr|C9J386|C9J386_HUMAN,tr|C9J0D1|C9J0D1_HUMAN,tr|A0A494C189|A0A494C189_HUMAN" 5 1125.5645 1.51 33770 18689 2 1125.564968 563.7895 Histone H2A.Z OS=Homo sapiens OX=9606 GN=H2AZ1 PE=1 SV=2 3.92 3169.2 - 2.56E+06 - - - 0.43 - 2.003 0.496 - 286.2 1 2 0 0.0005 10 0 0 0 1.26E+08 8.33E+07 - - - 4.6433 1 221125_WJC_METTL3_EV_vs_WT_F03.18690.18690.3 2.63E-05 13/52 K.THLPGFVEQAEALK[136.11].A sp|P30044|PRDX5_HUMAN 1 1546.8235 1.64 33771 18690 3 1546.824835 516.6151 "Peroxiredoxin-5, mitochondrial OS=Homo sapiens OX=9606 GN=PRDX5 PE=1 SV=4" 5.37 3169.2 - 2.47E+06 - - - 0.8676 - 2.445 0.454 - 292.6 1 2 0 0.0013 14 0 0 0 6.93E+07 4.21E+07 - - - 5.9772 1 221125_WJC_METTL3_EV_vs_WT_F03.18692.18692.3 3.84E-09 17/52 R.SLRPDPNFDALISK.L "sp|Q99496|RING2_HUMAN,sp|Q06587|RING1_HUMAN,tr|X6RFN3|X6RFN3_HUMAN" 3 1571.8308 1.82 33773 18692 3 1571.831455 524.9509 E3 ubiquitin-protein ligase RING2 OS=Homo sapiens OX=9606 GN=RNF2 PE=1 SV=1 5.68 3169.4 - 1.61E+06 - - - 0.4441 - 2.729 0.582 - 458.8 1 2 0 0.0007 14 0 0 0 1.57E+07 8.65E+06 - - - 7.6965 1 221125_WJC_METTL3_EV_vs_WT_F03.18693.18693.3 1.34E-08 14/56 R.NPDDITQEEYGEFYK[136.11].S sp|P08238|HS90B_HUMAN 1 1854.8039 1.23 33774 18693 3 1854.805521 619.2753 Heat shock protein HSP 90-beta OS=Homo sapiens OX=9606 GN=HSP90AB1 PE=1 SV=4 3.83 3169.5 - 1.48E+06 - - - 0.8524 - 2.561 0.613 - 244.7 1 2 0 0.0016 15 0 0 0 1.22E+07 9.94E+06 - - - 7.8277 1 221125_WJC_METTL3_EV_vs_WT_F03.18694.18694.2 1.80E-07 16/28 R.YDGQVAVFGSDLQEK[136.11].L sp|P22314|UBA1_HUMAN 1 1662.7981 2.1 33775 18694 2 1662.799107 832.4063 Ubiquitin-like modifier-activating enzyme 1 OS=Homo sapiens OX=9606 GN=UBA1 PE=1 SV=3 4.03 3169.6 - 1.42E+06 - - - 0.6261 - 2.97 0.629 - 898.1 1 2 0 0.001 15 0 0 0 1.35E+08 6.42E+07 - - - 6.3627 1 221125_WJC_METTL3_EV_vs_WT_F03.18695.18695.3 0.00417 13/36 R.ASLLGDMHFR.S sp|P51116|FXR2_HUMAN 1 1145.5652 1.16 33776 18695 3 1145.565045 382.8623 Fragile X mental retardation syndrome-related protein 2 OS=Homo sapiens OX=9606 GN=FXR2 PE=1 SV=2 6.79 3169.7 - 1.19E+06 - - - -0.103 - 2.797 0.452 - 268.8 1 2 0 -0.0001 10 0 0 0 1.47E+07 1.27E+07 - - - 6.5831 0.9999 221125_WJC_METTL3_EV_vs_WT_F03.18697.18697.3 0.0486 14/36 R.ASLLGDMHFR[166.11].S sp|P51116|FXR2_HUMAN 1 1155.5734 1.2 33778 18697 3 1155.572697 386.1984 Fragile X mental retardation syndrome-related protein 2 OS=Homo sapiens OX=9606 GN=FXR2 PE=1 SV=2 6.79 3169.9 - 1.11E+06 - - - -0.6369 - 2.797 0.315 - 307.7 1 2 0 -0.0007 10 0 0 0 1.52E+07 1.27E+07 - - - 5.0555 0.9967 221125_WJC_METTL3_EV_vs_WT_F03.18698.18698.2 0.00653 24-Sep K.QSPLNINGASYLR[166.11].L "sp|Q6W2J9|BCOR_HUMAN,tr|H7BZ37|H7BZ37_HUMAN,tr|H7C2V9|H7C2V9_HUMAN,tr|A0A5F9ZGX7|A0A5F9ZGX7_HUMAN,tr|H7BYY2|H7BYY2_HUMAN,tr|H7C231|H7C231_HUMAN" 6 1441.7553 1.49 33779 18698 2 1441.752064 721.8849 BCL-6 corepressor OS=Homo sapiens OX=9606 GN=BCOR PE=1 SV=1 8.75 3170 - 2.10E+06 - - - -2.2424 - 1.567 0.265 - 91.3 1 2 0 -0.0032 13 0 0 0 5.63E+07 3.77E+07 - - - 2.1501 1 221125_WJC_METTL3_EV_vs_WT_F03.18699.18699.2 2.10E-05 18/30 K.AAFGEEVDAVDTGISR[166.11].E sp|O00273|DFFA_HUMAN 1 1645.7823 1.02 33780 18699 2 1645.78067 823.8984 DNA fragmentation factor subunit alpha OS=Homo sapiens OX=9606 GN=DFFA PE=1 SV=1 3.92 3170.1 - 988781 - - - -0.9904 - 3.308 0.568 - 893.2 1 2 0 -0.0016 16 0 0 0 6.71E+06 6.60E+06 - - - 6.177 0.9996 221125_WJC_METTL3_EV_vs_WT_F03.18701.18701.3 0.000698 Nov-44 K.GVTQYYAYVTER[166.11].Q sp|P26196|DDX6_HUMAN 1 1458.7019 1.14 33782 18701 3 1458.699741 487.2412 Probable ATP-dependent RNA helicase DDX6 OS=Homo sapiens OX=9606 GN=DDX6 PE=1 SV=2 6 3170.3 - 899450 - - - -1.4561 - 1.947 0.34 - 146.9 1 2 0 -0.0021 12 0 0 0 4.60E+06 4.03E+06 - - - 4.1769 0.9996 221125_WJC_METTL3_EV_vs_WT_F03.18703.18703.2 0.000324 22-Aug R.GVDYNAEIPFEK.K sp|Q99459|CDC5L_HUMAN 1 1380.6561 2.11 33783 18703 2 1380.657365 691.3353 Cell division cycle 5-like protein OS=Homo sapiens OX=9606 GN=CDC5L PE=1 SV=2 4.14 3170.6 - 778304 - - - 0.8829 - 1.686 0.427 - 139.1 1 2 0 0.0012 12 0 0 0 1.45E+08 6.90E+07 - - - 3.5689 1 221125_WJC_METTL3_EV_vs_WT_F03.18704.18704.2 3.99E-08 15/26 K.YAFGSNVTPQPYLK.N sp|Q96BN2|TADA1_HUMAN 1 1583.7984 1.2 33784 18704 2 1583.805956 792.9065 Transcriptional adapter 1 OS=Homo sapiens OX=9606 GN=TADA1 PE=1 SV=1 8.5 3170.8 - 1.22E+06 - - - 4.7746 - 2.541 0.644 - 714.8 1 2 0 0.0076 14 0 0 0 7.75E+06 6.47E+06 - - - 6.1354 0.9981 221125_WJC_METTL3_EV_vs_WT_F03.18705.18705.3 5.88E-07 14/44 V.KLALDVEIATYR.K "sp|P48668|K2C6C_HUMAN,sp|Q01546|K22O_HUMAN,sp|P12035|K2C3_HUMAN,sp|P04259|K2C6B_HUMAN,sp|P13647|K2C5_HUMAN,sp|P35908|K22E_HUMAN,sp|O95678|K2C75_HUMAN,sp|Q5XKE5|K2C79_HUMAN,sp|P02538|K2C6A_HUMAN,tr|H0YI76|H0YI76_HUMAN,tr|H0YID6|H0YID6_HUMAN" 11 1390.782 8.11 33785 18705 3 1390.782327 464.6013 "Keratin, type II cytoskeletal 6C OS=Homo sapiens OX=9606 GN=KRT6C PE=1 SV=3" 6.07 3170.8 - 7.57E+06 - - - 0.2236 - 2.835 0.521 - 406.4 1 1 0 0.0003 12 0 0 0 7.98E+07 9.84E+06 - - - 7.2369 0.9997 221125_WJC_METTL3_EV_vs_WT_F03.18706.18706.2 6.93E-05 18-Nov K.SADTLWDIQK[136.11].D "sp|P07195|LDHB_HUMAN,tr|A0A5F9ZHM4|A0A5F9ZHM4_HUMAN" 2 1183.5965 0.49 33786 18706 2 1183.594063 592.8055 L-lactate dehydrogenase B chain OS=Homo sapiens OX=9606 GN=LDHB PE=1 SV=2 4.21 3170.8 - 7.33E+06 - - - -2.0193 - 2.047 0.485 - 454.1 1 2 0 -0.0024 10 0 0 0 2.15E+07 4.35E+07 - - - 4.6221 1 221125_WJC_METTL3_EV_vs_WT_F03.18709.18709.2 3.36E-06 24-Dec K.EQLDNQLDAYMSK[136.11].T "sp|Q9Y3Y2|CHTOP_HUMAN,tr|X6R700|X6R700_HUMAN" 2 1561.7174 3.92 33789 18709 2 1561.717791 781.866 Chromatin target of PRMT1 protein OS=Homo sapiens OX=9606 GN=CHTOP PE=1 SV=2 4.03 3171 - 2.46E+06 - - - 0.2677 - 2.702 0.565 - 566.8 1 2 0 0.0004 13 0 0 0 6.02E+07 1.54E+07 - - - 5.7651 1 221125_WJC_METTL3_EV_vs_WT_F03.18711.18711.2 2.03E-09 14/24 K.FDTTPNELVQLNK.L "sp|Q8N573|OXR1_HUMAN,tr|E5RII8|E5RII8_HUMAN" 2 1517.7726 0.99 33791 18711 2 1517.773143 759.8936 Oxidation resistance protein 1 OS=Homo sapiens OX=9606 GN=OXR1 PE=1 SV=2 4.37 3171.3 - 1.47E+06 - - - 0.3756 - 2.773 0.621 - 742.5 1 2 0 0.0006 13 0 0 0 8.90E+06 9.03E+06 - - - 6.2452 0.9988 221125_WJC_METTL3_EV_vs_WT_F03.18712.18712.3 0.000584 Sep-56 K.ETIPLQETSLYTQDR.L "sp|P50897|PPT1_HUMAN,tr|A0A2C9F2P4|A0A2C9F2P4_HUMAN,tr|E9PIA8|E9PIA8_HUMAN,tr|A0A286YFF7|A0A286YFF7_HUMAN,tr|E9PSE5|E9PSE5_HUMAN" 5 1792.8843 2.49 33792 18712 3 1792.886544 598.6354 Palmitoyl-protein thioesterase 1 OS=Homo sapiens OX=9606 GN=PPT1 PE=1 SV=1 4.14 3171.4 - 1.41E+06 - - - 1.2466 - 1.844 0.289 - 62.6 1 2 0 0.0022 15 0 0 0 5.42E+06 2.17E+06 - - - 3.3582 1 221125_WJC_METTL3_EV_vs_WT_F03.18714.18714.2 2.07E-09 13/24 K.FDTTPNELVQLNK[136.11].L "sp|Q8N573|OXR1_HUMAN,tr|E5RII8|E5RII8_HUMAN" 2 1525.7868 1.05 33794 18714 2 1525.785896 763.9007 Oxidation resistance protein 1 OS=Homo sapiens OX=9606 GN=OXR1 PE=1 SV=2 4.37 3171.6 - 1.37E+06 - - - -0.5748 - 2.595 0.636 - 639.7 1 2 0 -0.0009 13 0 0 0 8.14E+06 7.73E+06 - - - 6.1856 1 221125_WJC_METTL3_EV_vs_WT_F03.18715.18715.3 1.14E-06 18/48 K.MFVGGLSWDTSKK.D "sp|Q99729|ROAA_HUMAN,tr|D6R9P3|D6R9P3_HUMAN,tr|D6RD18|D6RD18_HUMAN,tr|D6RBZ0|D6RBZ0_HUMAN" 4 1454.7228 0.48 33795 18715 3 1454.721608 485.9149 Heterogeneous nuclear ribonucleoprotein A\B OS=Homo sapiens OX=9606 GN=HNRNPAB PE=1 SV=2 8.35 3171.7 - 1.22E+06 - - - -0.8098 - 3.008 0.545 - 407.7 1 2 0 -0.0012 13 0 0 0 2.95E+07 6.12E+07 - - - 7.6018 1 221125_WJC_METTL3_EV_vs_WT_F03.18716.18716.3 2.45E-09 15/52 R.SLR[166.11]PDPNFDALISK[136.11].L "sp|Q99496|RING2_HUMAN,sp|Q06587|RING1_HUMAN,tr|X6RFN3|X6RFN3_HUMAN" 3 1589.8532 1.88 33796 18716 3 1589.854648 530.9584 E3 ubiquitin-protein ligase RING2 OS=Homo sapiens OX=9606 GN=RNF2 PE=1 SV=1 5.68 3171.7 - 1.22E+06 - - - 0.8938 - 2.467 0.562 - 309.6 1 2 0 0.0014 14 0 0 0 1.54E+07 8.23E+06 - - - 7.2051 1 221125_WJC_METTL3_EV_vs_WT_F03.18717.18717.2 7.78E-13 18/34 K.IGVSSDSGSINPMSEGFK[136.11].F sp|P49790|NU153_HUMAN 1 1818.8549 0.9 33797 18717 2 1818.853522 910.4347 Nuclear pore complex protein Nup153 OS=Homo sapiens OX=9606 GN=NUP153 PE=1 SV=2 4.37 3171.9 - 1.18E+06 - - - -0.7736 - 3.703 0.714 - 876.7 1 2 0 -0.0014 18 0 0 0 9.01E+06 1.00E+07 - - - 7.5328 0.9935 221125_WJC_METTL3_EV_vs_WT_F03.18718.18718.2 0.129 17/22 V.KLALDVEIATYR.K "sp|P48668|K2C6C_HUMAN,sp|Q01546|K22O_HUMAN,sp|P12035|K2C3_HUMAN,sp|P04259|K2C6B_HUMAN,sp|P13647|K2C5_HUMAN,sp|P35908|K22E_HUMAN,sp|O95678|K2C75_HUMAN,sp|Q5XKE5|K2C79_HUMAN,sp|P02538|K2C6A_HUMAN,tr|H0YI76|H0YI76_HUMAN,tr|H0YID6|H0YID6_HUMAN" 11 1390.782 115.04 33798 18718 2 1390.780636 696.3983 "Keratin, type II cytoskeletal 6C OS=Homo sapiens OX=9606 GN=KRT6C PE=1 SV=3" 6.07 3172 - 1.17E+06 - - - -0.9922 - 2.992 0.476 - 1040.5 1 1 0 -0.0014 12 0 0 0 1.51E+07 1.31E+05 - - - 5.4399 0.9999 221125_WJC_METTL3_EV_vs_WT_F03.18720.18720.2 2.28E-05 16/24 R.NILSVVGTDALK[136.11]K[136.11].T sp|O43172|PRP4_HUMAN 1 1372.8261 2.9 33800 18720 2 1372.826529 687.4203 U4\U6 small nuclear ribonucleoprotein Prp4 OS=Homo sapiens OX=9606 GN=PRPF4 PE=1 SV=2 8.59 3172.3 - 1.08E+06 - - - 0.3373 - 2.5 0.473 - 644.9 1 2 0 0.0005 13 0 0 0 3.09E+07 1.06E+07 - - - 4.8861 1 221125_WJC_METTL3_EV_vs_WT_F03.18721.18721.2 9.27E-08 15/26 K.YAFGSNVTPQPYLK[136.11].N sp|Q96BN2|TADA1_HUMAN 1 1591.8126 1.2 33801 18721 2 1591.812897 796.9136 Transcriptional adapter 1 OS=Homo sapiens OX=9606 GN=TADA1 PE=1 SV=1 8.5 3172.4 - 961583 - - - 0.1903 - 2.645 0.606 - 738.2 1 2 0 0.0003 14 0 0 0 7.75E+06 6.47E+06 - - - 5.9577 0.9999 221125_WJC_METTL3_EV_vs_WT_F03.18722.18722.3 0.000193 Dec-36 K.DVLDVYIEHR[166.11].L sp|P33993|MCM7_HUMAN 1 1267.6436 1.16 33802 18722 3 1267.644187 423.5552 DNA replication licensing factor MCM7 OS=Homo sapiens OX=9606 GN=MCM7 PE=1 SV=4 4.54 3172.5 - 933680 - - - 0.4465 - 2.373 0.416 - 214.4 1 2 0 0.0006 10 0 0 0 5.03E+06 4.32E+06 - - - 5.7015 1 221125_WJC_METTL3_EV_vs_WT_F03.18724.18724.3 0.000352 14/52 K.IAILTC[160.03]PFEPPKPK.T "sp|P48643|TCPE_HUMAN,tr|E9PCA1|E9PCA1_HUMAN,tr|B7ZAR1|B7ZAR1_HUMAN,tr|E7ENZ3|E7ENZ3_HUMAN" 4 1609.8902 0.69 33803 18724 3 1609.890914 537.6373 T-complex protein 1 subunit epsilon OS=Homo sapiens OX=9606 GN=CCT5 PE=1 SV=1 8.2 3172.7 - 2.87E+06 - - - 0.4522 - 2.629 0.48 - 258.2 1 2 0 0.0007 14 0 0 0 2.67E+07 3.89E+07 - - - 6.4601 0.9999 221125_WJC_METTL3_EV_vs_WT_F03.18726.18726.2 1.71E-05 22-Dec K.NYIQGINLVQAK.K "sp|P52815|RM12_HUMAN,tr|B4DLN1|B4DLN1_HUMAN" 2 1359.7511 1.99 33805 18726 2 1359.751069 680.8828 "39S ribosomal protein L12, mitochondrial OS=Homo sapiens OX=9606 GN=MRPL12 PE=1 SV=2" 8.59 3172.9 - 9.99E+06 - - - 0.014 - 2.407 0.526 - 372.7 1 2 0 0 12 0 0 0 5.29E+08 2.66E+08 - - - 5.2372 0.9999 221125_WJC_METTL3_EV_vs_WT_F03.18727.18727.2 0.000593 22-Dec K.NYIQGINLVQAK[136.11].K "sp|P52815|RM12_HUMAN,tr|B4DLN1|B4DLN1_HUMAN" 2 1367.7652 2 33806 18727 2 1367.765508 684.8899 "39S ribosomal protein L12, mitochondrial OS=Homo sapiens OX=9606 GN=MRPL12 PE=1 SV=2" 8.59 3172.9 - 6.24E+06 - - - 0.1886 - 2.145 0.485 - 408.1 1 2 0 0.0003 12 0 0 0 5.32E+08 2.66E+08 - - - 4.6311 1 221125_WJC_METTL3_EV_vs_WT_F03.18728.18728.3 5.41E-09 23/80 R.ATGEADVEFVTHEDAVAAMSK.D sp|P31942|HNRH3_HUMAN 1 2176.9947 2.6 33807 18728 3 2176.995357 726.6722 Heterogeneous nuclear ribonucleoprotein H3 OS=Homo sapiens OX=9606 GN=HNRNPH3 PE=1 SV=2 4.17 3173 - 6.17E+06 - - - 0.3183 - 4.988 0.63 - 892.3 1 2 0 0.0007 21 0 0 0 4.04E+07 1.55E+07 - - - 9.4165 1 221125_WJC_METTL3_EV_vs_WT_F03.18729.18729.2 9.05E-07 15/22 K.WMEEQAQSLIDK.T "sp|P09234|RU1C_HUMAN,tr|A0A0A0MRR7|A0A0A0MRR7_HUMAN" 2 1476.6919 1.4 33808 18729 2 1476.691694 739.3532 U1 small nuclear ribonucleoprotein C OS=Homo sapiens OX=9606 GN=SNRPC PE=1 SV=1 4.14 3173.1 - 3.60E+06 - - - -0.126 - 2.79 0.592 - 864.2 1 2 0 -0.0002 12 0 0 0 3.56E+07 2.53E+07 - - - 6.1131 1 221125_WJC_METTL3_EV_vs_WT_F03.18730.18730.3 4.02E-09 27/80 R.ATGEADVEFVTHEDAVAAMSK[136.11].D sp|P31942|HNRH3_HUMAN 1 2185.0089 2.73 33809 18730 3 2185.008008 729.3436 Heterogeneous nuclear ribonucleoprotein H3 OS=Homo sapiens OX=9606 GN=HNRNPH3 PE=1 SV=2 4.17 3173.1 - 3.25E+06 - - - -0.3918 - 5.069 0.66 - 1322.2 1 2 0 -0.0009 21 0 0 0 3.99E+07 1.46E+07 - - - 9.7895 1 221125_WJC_METTL3_EV_vs_WT_F03.18731.18731.2 5.18E-10 18/28 K.NYTDEAIETDDLTIK.L "sp|O14818|PSA7_HUMAN,tr|H0Y586|H0Y586_HUMAN" 2 1739.8101 0.67 33810 18731 2 1739.809374 870.9123 Proteasome subunit alpha type-7 OS=Homo sapiens OX=9606 GN=PSMA7 PE=1 SV=1 3.77 3173.2 - 1.84E+06 - - - -0.4409 - 3.54 0.64 - 963.1 1 2 0 -0.0008 15 0 0 0 1.75E+07 2.62E+07 - - - 6.8757 0.9999 221125_WJC_METTL3_EV_vs_WT_F03.18732.18732.2 2.89E-06 18-Dec K.LNC[160.03]FLEQDLK.L "sp|P52732|KIF11_HUMAN,tr|A0A7I2V3A9|A0A7I2V3A9_HUMAN" 2 1278.6278 3.68 33811 18732 2 1278.627259 640.3212 Kinesin-like protein KIF11 OS=Homo sapiens OX=9606 GN=KIF11 PE=1 SV=2 4.37 3173.3 - 1.78E+06 - - - -0.4411 - 2.824 0.433 - 957.1 1 2 0 -0.0006 10 0 0 0 2.42E+07 6.57E+06 - - - 5.1368 0.9993 221125_WJC_METTL3_EV_vs_WT_F03.18733.18733.3 0.000786 13/40 K.WEGLVYAPPGK.E "sp|Q9Y2W1|TR150_HUMAN,tr|A0A3B3ITZ9|A0A3B3ITZ9_HUMAN" 2 1215.6288 2.81 33812 18733 3 1215.62809 406.2169 Thyroid hormone receptor-associated protein 3 OS=Homo sapiens OX=9606 GN=THRAP3 PE=1 SV=2 6 3173.4 - 1.29E+06 - - - -0.5915 - 2.402 0.226 - 227.1 1 2 0 -0.0007 11 0 0 0 6.31E+06 2.24E+06 - - - 3.5489 0.9999 221125_WJC_METTL3_EV_vs_WT_F03.18735.18735.2 7.50E-06 28-Nov K.ETIPLQETSLYTQDR[166.11].L "sp|P50897|PPT1_HUMAN,tr|A0A2C9F2P4|A0A2C9F2P4_HUMAN,tr|E9PIA8|E9PIA8_HUMAN,tr|A0A286YFF7|A0A286YFF7_HUMAN,tr|E9PSE5|E9PSE5_HUMAN" 5 1802.8926 1.32 33814 18735 2 1802.892542 902.4536 Palmitoyl-protein thioesterase 1 OS=Homo sapiens OX=9606 GN=PPT1 PE=1 SV=1 4.14 3173.7 - 1.14E+06 - - - -0.0205 - 2.374 0.497 - 362 1 2 0 0 15 0 0 0 8.63E+06 6.54E+06 - - - 4.8374 1 221125_WJC_METTL3_EV_vs_WT_F03.18736.18736.2 3.77E-10 18/30 R.SAYGGLQTSSYLMSTR.S sp|P07196|NFL_HUMAN 1 1720.809 1.7 33815 18736 2 1720.810106 861.4118 Neurofilament light polypeptide OS=Homo sapiens OX=9606 GN=NEFL PE=1 SV=3 8.31 3173.9 - 895973 - - - 0.6224 - 3.554 0.58 - 928.7 1 2 0 0.0011 16 0 0 0 1.31E+07 7.67E+06 - - - 6.4422 0.9992 221125_WJC_METTL3_EV_vs_WT_F03.18737.18737.2 0.0093 22-Oct R.SGWTSASSWAVR[166.11].K "sp|Q99590|SCAFB_HUMAN,tr|F8VXG7|F8VXG7_HUMAN" 2 1303.6185 1.03 33816 18737 2 1303.61872 652.8165 Protein SCAF11 OS=Homo sapiens OX=9606 GN=SCAF11 PE=1 SV=2 9.47 3174 - 697446 - - - 0.1925 - 1.544 0.323 - 173.2 1 2 0 0.0003 12 0 0 0 5.21E+06 5.07E+06 - - - 2.5695 1 221125_WJC_METTL3_EV_vs_WT_F03.18738.18738.2 2.30E-11 20/30 R.SAYGGLQTSSYLMSTR[166.11].S sp|P07196|NFL_HUMAN 1 1730.8173 1.7 33817 18738 2 1730.810415 866.4159 Neurofilament light polypeptide OS=Homo sapiens OX=9606 GN=NEFL PE=1 SV=3 8.31 3174.1 - 503003 - - - -3.9808 - 3.327 0.688 - 944.5 1 2 0 -0.0069 16 0 0 0 1.31E+07 7.67E+06 - - - 7.0758 0.9982 221125_WJC_METTL3_EV_vs_WT_F03.18740.18740.3 0.0317 Nov-40 K.WEGLVYAPPGK[136.11].E "sp|Q9Y2W1|TR150_HUMAN,tr|A0A3B3ITZ9|A0A3B3ITZ9_HUMAN" 2 1223.643 2.95 33819 18740 3 1223.640725 408.8883 Thyroid hormone receptor-associated protein 3 OS=Homo sapiens OX=9606 GN=THRAP3 PE=1 SV=2 6 3174.4 - 512473 - - - -1.8666 - 1.843 0.268 - 127.7 1 2 0 -0.0023 11 0 0 0 5.77E+06 1.96E+06 - - - 3.2642 0.9889 221125_WJC_METTL3_EV_vs_WT_F03.18741.18741.2 0.00125 13/28 R.LEEAC[160.03]DMALELNASK[136.11].H "sp|Q8WWY3|PRP31_HUMAN,tr|E7EVX8|E7EVX8_HUMAN,tr|E7EU94|E7EU94_HUMAN,tr|E7ESX0|E7ESX0_HUMAN,tr|E7EN72|E7EN72_HUMAN" 5 1700.7841 -1 33820 18741 2 1701.785062 851.3993 U4\U6 small nuclear ribonucleoprotein Prp31 OS=Homo sapiens OX=9606 GN=PRPF31 PE=1 SV=2 4 3174.5 - 372383 - - - 588.5456 - 2.551 0.426 - 386.2 1 2 0 1.001 15 0 0 0 0.00E+00 0.00E+00 - - - 4.1755 0.927 221125_WJC_METTL3_EV_vs_WT_F03.18742.18742.3 0.0115 Dec-44 R.EHALLAYTLGVK[136.11].Q "sp|Q05639|EF1A2_HUMAN,sp|P68104|EF1A1_HUMAN,sp|Q5VTE0|EF1A3_HUMAN,tr|A0A2R8Y488|A0A2R8Y488_HUMAN,tr|A0A7I2V659|A0A7I2V659_HUMAN,tr|A0A7I2V3H3|A0A7I2V3H3_HUMAN,tr|A0A2U3TZH3|A0A2U3TZH3_HUMAN,tr|A0A7I2V5N4|A0A7I2V5N4_HUMAN,tr|A0A087WVQ9|A0A087WVQ9_HUMAN,tr|A0A087WV01|A0A087WV01_HUMAN,tr|A0A2R8Y660|A0A2R8Y660_HUMAN" 11 1321.7485 -1 33821 18742 3 1322.747286 441.5901 Elongation factor 1-alpha 2 OS=Homo sapiens OX=9606 GN=EEF1A2 PE=1 SV=1 6.85 3174.6 - 355785 - - - 755.6271 - 1.89 0.339 - 160.2 1 2 0 0.9987 12 0 0 0 0.00E+00 0.00E+00 - - - 3.8074 0.9999 221125_WJC_METTL3_EV_vs_WT_F03.18743.18743.2 1.92E-07 Nov-32 R.GSTAPVGGGAFPTIVER[166.11].E sp|Q15084|PDIA6_HUMAN 1 1624.8448 1.88 33822 18743 2 1624.845415 813.4297 Protein disulfide-isomerase A6 OS=Homo sapiens OX=9606 GN=PDIA6 PE=1 SV=1 6 3174.8 - 346660 - - - 0.3539 - 2.398 0.537 - 280.3 1 2 0 0.0006 17 0 0 0 1.29E+07 6.84E+06 - - - 5.1574 0.9949 221125_WJC_METTL3_EV_vs_WT_F03.18745.18745.3 0.124 Oct-48 R.R[166.11]IGFDVVTLSGTR[166.11].G "sp|Q9BSD7|NTPCR_HUMAN,tr|Q5TDF0|Q5TDF0_HUMAN" 2 1439.8 1.88 33823 18745 3 1439.799888 480.9406 Cancer-related nucleoside-triphosphatase OS=Homo sapiens OX=9606 GN=NTPCR PE=1 SV=1 9.6 3175 - 1.21E+07 - - - -0.0451 - 1.994 0.162 - 159.4 1 2 0 -0.0001 13 0 0 0 2.02E+08 1.07E+08 - - - 2.2173 1 221125_WJC_METTL3_EV_vs_WT_F03.18746.18746.2 1.82E-08 17/34 K.IGVSSDSGSINPMSEGFK.F sp|P49790|NU153_HUMAN 1 1810.8407 0.9 33824 18746 2 1810.84021 906.4276 Nuclear pore complex protein Nup153 OS=Homo sapiens OX=9606 GN=NUP153 PE=1 SV=2 4.37 3175 - 3.01E+06 - - - -0.2866 - 3.079 0.658 - 450.4 1 2 0 -0.0005 18 0 0 0 9.01E+06 1.00E+07 - - - 6.6657 0.9982 221125_WJC_METTL3_EV_vs_WT_F03.18747.18747.3 0.0114 Sep-40 K.EIKDILIQYDR.T "sp|P62249|RS16_HUMAN,tr|M0R210|M0R210_HUMAN" 2 1404.7613 0.92 33825 18747 3 1404.761779 469.261 40S ribosomal protein S16 OS=Homo sapiens OX=9606 GN=RPS16 PE=1 SV=2 4.56 3175.1 - 4.39E+06 - - - 0.3552 - 1.82 0.338 - 117.9 1 2 1 0.0005 11 0 0 0 1.48E+08 1.61E+08 - - - 4.0094 0.9998 221125_WJC_METTL3_EV_vs_WT_F03.18748.18748.2 0.00683 20-Nov K.MQLLQSLQEQK.K "sp|Q15643|TRIPB_HUMAN,tr|H0YJ97|H0YJ97_HUMAN" 2 1344.7071 1.04 33826 18748 2 1344.708537 673.3608 Thyroid receptor-interacting protein 11 OS=Homo sapiens OX=9606 GN=TRIP11 PE=1 SV=3 5.75 3175.1 - 3.25E+06 - - - 1.0419 - 2.194 0.426 - 445.3 1 2 0 0.0014 11 0 0 0 3.33E+07 3.20E+07 - - - 4.3126 1 221125_WJC_METTL3_EV_vs_WT_F03.18749.18749.3 1.06E-08 15/60 R.GLGHQVATDALVAMEK.A sp|Q9Y3I0|RTCB_HUMAN 1 1638.8399 1.39 33827 18749 3 1638.84327 547.2873 RNA-splicing ligase RtcB homolog OS=Homo sapiens OX=9606 GN=RTCB PE=1 SV=1 5.32 3175.2 - 1.98E+06 - - - 2.0313 - 3.152 0.623 - 238.8 1 2 0 0.0033 16 0 0 0 4.59E+07 3.31E+07 - - - 8.4306 1 221125_WJC_METTL3_EV_vs_WT_F03.18751.18751.3 1.90E-07 18/60 R.GLGHQVATDALVAMEK[136.11].A sp|Q9Y3I0|RTCB_HUMAN 1 1646.8541 1.86 33829 18751 3 1646.853733 549.9587 RNA-splicing ligase RtcB homolog OS=Homo sapiens OX=9606 GN=RTCB PE=1 SV=1 5.32 3175.3 - 1.49E+06 - - - -0.2477 - 3.403 0.554 - 566.4 1 2 0 -0.0004 16 0 0 0 4.57E+07 2.46E+07 - - - 7.8587 1 221125_WJC_METTL3_EV_vs_WT_F03.18752.18752.2 2.23E-09 16/24 K.LC[160.03]LNIC[160.03]VGESGDR.L "sp|P62913|RL11_HUMAN,tr|Q5VVC8|Q5VVC8_HUMAN" 2 1491.681 1.06 33830 18752 2 1491.671765 746.8478 60S ribosomal protein L11 OS=Homo sapiens OX=9606 GN=RPL11 PE=1 SV=2 4.37 3175.5 - 1.48E+06 - - - -6.1897 - 3.08 0.645 - 1033.9 1 2 0 -0.0092 13 0 0 0 1.70E+07 1.59E+07 - - - 6.6892 0.9999 221125_WJC_METTL3_EV_vs_WT_F03.18753.18753.2 0.00153 13/24 K.LC[160.03]LNIC[160.03]VGESGDR[166.11].L "sp|P62913|RL11_HUMAN,tr|Q5VVC8|Q5VVC8_HUMAN" 2 1501.6893 1.33 33831 18753 2 1501.688092 751.8519 60S ribosomal protein L11 OS=Homo sapiens OX=9606 GN=RPL11 PE=1 SV=2 4.37 3175.6 - 1.28E+06 - - - -0.7831 - 2.587 0.449 - 595.3 1 2 0 -0.0012 13 0 0 0 2.23E+07 1.67E+07 - - - 4.7964 1 221125_WJC_METTL3_EV_vs_WT_F03.18754.18754.2 2.53E-09 16/28 R.LEEAC[160.03]DMALELNASK.H "sp|Q8WWY3|PRP31_HUMAN,tr|E7EVX8|E7EVX8_HUMAN,tr|E7EU94|E7EU94_HUMAN,tr|E7ESX0|E7ESX0_HUMAN,tr|E7EN72|E7EN72_HUMAN" 5 1692.7699 3.72 33832 18754 2 1692.768527 847.3922 U4\U6 small nuclear ribonucleoprotein Prp31 OS=Homo sapiens OX=9606 GN=PRPF31 PE=1 SV=2 4 3175.7 - 1.25E+06 - - - -0.7951 - 3.342 0.682 - 816.7 1 2 0 -0.0013 15 0 0 0 6.20E+06 1.67E+06 - - - 7.0442 0.9363 221125_WJC_METTL3_EV_vs_WT_F03.18755.18755.2 0.0151 24-Oct K.QIPFPSGTPLHAN.S "sp|Q12904|AIMP1_HUMAN,tr|A0A804HJ47|A0A804HJ47_HUMAN,tr|D6R937|D6R937_HUMAN,tr|A0A5F9ZHC5|A0A5F9ZHC5_HUMAN" 4 1377.7041 - 33833 18755 2 1377.706972 689.8593 Aminoacyl tRNA synthase complex-interacting multifunctional protein 1 OS=Homo sapiens OX=9606 GN=AIMP1 PE=1 SV=2 6.74 3175.8 - 1.12E+06 - - - 2.0846 - 1.873 0.332 - 229.5 1 1 0 0.0029 13 0 0 0 - - - - - 3.1029 0.9998 221125_WJC_METTL3_EV_vs_WT_F03.18756.18756.2 1.57E-05 18/26 R.LQEAGILSAEELQR[166.11].L "sp|Q15149|PLEC_HUMAN,tr|H0YDN1|H0YDN1_HUMAN" 2 1565.8289 2.46 33834 18756 2 1565.826208 783.9217 Plectin OS=Homo sapiens OX=9606 GN=PLEC PE=1 SV=3 4.25 3176 - 1.10E+06 - - - -1.6911 - 2.912 0.474 - 1287.4 1 2 0 -0.0026 14 0 0 0 7.66E+06 3.11E+06 - - - 5.2233 0.9999 221125_WJC_METTL3_EV_vs_WT_F03.18759.18759.3 3.83E-06 13/60 R.SAYGGLQTSSYLMSTR.S sp|P07196|NFL_HUMAN 1 1720.809 2.31 33837 18759 3 1720.804557 574.6103 Neurofilament light polypeptide OS=Homo sapiens OX=9606 GN=NEFL PE=1 SV=3 8.31 3176.4 - 830502 - - - -2.6023 - 2.38 0.455 - 188.7 1 2 0 -0.0045 16 0 0 0 4.23E+06 1.83E+06 - - - 5.8364 0.9831 221125_WJC_METTL3_EV_vs_WT_F03.18760.18760.2 3.33E-06 13/22 Y.NSTSQAFAEVLR.L "sp|Q8N3Z3|GTPB8_HUMAN,tr|F8WBY6|F8WBY6_HUMAN,tr|A0A087WUP3|A0A087WUP3_HUMAN" 3 1321.6626 0.93 33838 18760 2 1321.659138 661.8386 GTP-binding protein 8 OS=Homo sapiens OX=9606 GN=GTPBP8 PE=1 SV=1 6 3176.5 - 596417 - - - -2.6414 - 2.615 0.555 - 885.7 1 1 0 -0.0035 12 0 0 0 5.53E+06 5.95E+06 - - - 5.6684 0.9971 221125_WJC_METTL3_EV_vs_WT_F03.18761.18761.3 4.57E-07 16/40 A.TEHYSPLSLLK.Q "sp|Q8NBP0|TTC13_HUMAN,tr|E5RJP6|E5RJP6_HUMAN,tr|H0YBV3|H0YBV3_HUMAN,tr|E5RHB3|E5RHB3_HUMAN,tr|E5RG15|E5RG15_HUMAN" 5 1286.6871 1.09 33839 18761 3 1286.685226 429.903 Tetratricopeptide repeat protein 13 OS=Homo sapiens OX=9606 GN=TTC13 PE=2 SV=3 6.41 3176.6 - 402057 - - - -1.4199 - 2.49 0.519 - 453 1 1 0 -0.0018 11 0 0 0 2.30E+06 2.11E+06 - - - 6.9175 0.9962 221125_WJC_METTL3_EV_vs_WT_F03.18762.18762.2 0.0224 24-Sep K.EFLMNTLNQSDTK[136.11].T "sp|O94913|PCF11_HUMAN,tr|E9PKN0|E9PKN0_HUMAN,tr|E9PQ01|E9PQ01_HUMAN" 3 1547.7381 -1 33840 18762 2 1547.73422 774.8763 Pre-mRNA cleavage complex 2 protein Pcf11 OS=Homo sapiens OX=9606 GN=PCF11 PE=1 SV=3 4.37 3176.8 - 374593 - - - -2.5121 - 1.41 0.307 - 186.8 1 2 0 -0.0039 13 0 0 0 0.00E+00 0.00E+00 - - - 2.1891 1 221125_WJC_METTL3_EV_vs_WT_F03.18766.18766.2 3.80E-08 17/26 K.QGGPTYYIDTNALR[166.11].V "sp|O96019|ACL6A_HUMAN,tr|C9JQT2|C9JQT2_HUMAN,tr|H7C5S0|H7C5S0_HUMAN" 3 1577.7713 0.84 33843 18766 2 1577.772483 789.8929 Actin-like protein 6A OS=Homo sapiens OX=9606 GN=ACTL6A PE=1 SV=1 5.83 3177.2 - 1.18E+06 - - - 0.7238 - 3.136 0.64 - 1032.1 1 2 0 0.0011 14 0 0 0 6.92E+06 8.22E+06 - - - 6.6359 0.9999 221125_WJC_METTL3_EV_vs_WT_F03.18767.18767.2 7.41E-06 18-Sep R.GDEELDSLIK.A "sp|P0C0S5|H2AZ_HUMAN,sp|Q71UI9|H2AV_HUMAN,tr|C9J386|C9J386_HUMAN,tr|C9J0D1|C9J0D1_HUMAN,tr|A0A494C189|A0A494C189_HUMAN" 5 1117.5503 1.51 33844 18767 2 1117.550314 559.7824 Histone H2A.Z OS=Homo sapiens OX=9606 GN=H2AZ1 PE=1 SV=2 3.92 3177.3 - 2.01E+07 - - - 0.0268 - 2.231 0.521 - 439.6 1 2 0 0 10 0 0 0 1.26E+08 8.33E+07 - - - 5.129 0.9998 221125_WJC_METTL3_EV_vs_WT_F03.18768.18768.2 7.52E-05 20-Dec K.MQLLQSLQEQK[136.11].K "sp|Q15643|TRIPB_HUMAN,tr|H0YJ97|H0YJ97_HUMAN" 2 1352.7213 1.04 33845 18768 2 1352.722172 677.3679 Thyroid receptor-interacting protein 11 OS=Homo sapiens OX=9606 GN=TRIP11 PE=1 SV=3 5.75 3177.3 - 5.72E+06 - - - 0.618 - 2.355 0.417 - 508.6 1 2 0 0.0008 11 0 0 0 3.33E+07 3.20E+07 - - - 4.4378 0.9999 221125_WJC_METTL3_EV_vs_WT_F03.18769.18769.2 1.15E-08 13/22 K.WMEEQAQSLIDK[136.11].T "sp|P09234|RU1C_HUMAN,tr|A0A0A0MRR7|A0A0A0MRR7_HUMAN" 2 1484.7061 1.47 33846 18769 2 1484.707462 743.3603 U1 small nuclear ribonucleoprotein C OS=Homo sapiens OX=9606 GN=SNRPC PE=1 SV=1 4.14 3177.4 - 5.66E+06 - - - 0.9308 - 2.637 0.522 - 573.8 1 2 0 0.0014 12 0 0 0 3.72E+07 2.53E+07 - - - 5.4474 1 221125_WJC_METTL3_EV_vs_WT_F03.18770.18770.2 2.17E-15 17/28 R.NPDDITQEEYGEFYK.S sp|P08238|HS90B_HUMAN 1 1846.7897 0.95 33847 18770 2 1846.789241 924.4021 Heat shock protein HSP 90-beta OS=Homo sapiens OX=9606 GN=HSP90AB1 PE=1 SV=4 3.83 3177.4 - 4.97E+06 - - - -0.2702 - 3.566 0.633 - 1178.3 1 2 0 -0.0005 15 0 0 0 7.12E+07 7.53E+07 - - - 6.8421 0.9965 221125_WJC_METTL3_EV_vs_WT_F03.18771.18771.2 0.000807 20-Nov K.EIK[136.11]DILIQYDR[166.11].T "sp|P62249|RS16_HUMAN,tr|M0R210|M0R210_HUMAN" 2 1422.7838 0.85 33848 18771 2 1422.781601 712.3992 40S ribosomal protein S16 OS=Homo sapiens OX=9606 GN=RPS16 PE=1 SV=2 4.56 3177.5 - 3.75E+06 - - - -1.5104 - 2.155 0.4 - 361.1 1 2 1 -0.0022 11 0 0 0 2.54E+07 3.00E+07 - - - 4.0718 1 221125_WJC_METTL3_EV_vs_WT_F03.18773.18773.2 9.96E-10 14/32 R.GSTAPVGGGAFPTIVER.E sp|Q15084|PDIA6_HUMAN 1 1614.8366 1.88 33850 18773 2 1614.837989 808.4256 Protein disulfide-isomerase A6 OS=Homo sapiens OX=9606 GN=PDIA6 PE=1 SV=1 6 3177.6 - 2.87E+06 - - - 0.8787 - 2.577 0.609 - 472.6 1 2 0 0.0014 17 0 0 0 1.29E+07 6.84E+06 - - - 5.866 0.9999 221125_WJC_METTL3_EV_vs_WT_F03.18774.18774.3 0.00244 Nov-44 R.NQYVTLHDMILK[136.11].N "sp|P61289|PSME3_HUMAN,tr|B3KQ25|B3KQ25_HUMAN,tr|K7ESG5|K7ESG5_HUMAN,tr|K9J957|K9J957_HUMAN,tr|A0A087WTV2|A0A087WTV2_HUMAN" 5 1481.7792 1.26 33851 18774 3 1481.780549 494.9337 Proteasome activator complex subunit 3 OS=Homo sapiens OX=9606 GN=PSME3 PE=1 SV=1 6.74 3177.7 - 2.82E+06 - - - 0.9205 - 2.358 0.433 - 161.7 1 2 0 0.0014 12 0 0 0 1.67E+07 1.33E+07 - - - 5.7449 1 221125_WJC_METTL3_EV_vs_WT_F03.18775.18775.2 3.33E-07 24-Dec R.VDSTTC[160.03]LFPVEEK.A "sp|Q06210|GFPT1_HUMAN,tr|A0A6I8PRN4|A0A6I8PRN4_HUMAN,tr|A0A6I8PTT9|A0A6I8PTT9_HUMAN" 3 1523.7178 1.43 33852 18775 2 1523.715196 762.8662 Glutamine--fructose-6-phosphate aminotransferase [isomerizing] 1 OS=Homo sapiens OX=9606 GN=GFPT1 PE=1 SV=3 4.14 3177.8 - 2.59E+06 - - - -1.6834 - 2.733 0.62 - 483.3 1 2 0 -0.0026 13 0 0 0 1.31E+07 9.17E+06 - - - 6.1999 1 221125_WJC_METTL3_EV_vs_WT_F03.18776.18776.2 8.49E-07 16/32 K.SLTINGVADDDALAEER.M "sp|O75190|DNJB6_HUMAN,tr|A0A0J9YX62|A0A0J9YX62_HUMAN" 2 1787.8537 1.36 33853 18776 2 1787.851922 894.9341 DnaJ homolog subfamily B member 6 OS=Homo sapiens OX=9606 GN=DNAJB6 PE=1 SV=2 3.77 3177.8 - 2.50E+06 - - - -1.0152 - 3.222 0.648 - 751.4 1 2 0 -0.0018 17 0 0 0 1.09E+07 8.03E+06 - - - 6.7031 0.9968 221125_WJC_METTL3_EV_vs_WT_F03.18777.18777.2 0.0719 20-Dec K.EIKDILIQYDR.T "sp|P62249|RS16_HUMAN,tr|M0R210|M0R210_HUMAN" 2 1404.7613 0.85 33854 18777 2 1404.763231 703.3879 40S ribosomal protein S16 OS=Homo sapiens OX=9606 GN=RPS16 PE=1 SV=2 4.56 3177.9 - 2.20E+06 - - - 1.3888 - 2.38 0.389 - 460.6 1 2 1 0.002 11 0 0 0 2.54E+07 3.00E+07 - - - 4.2593 1 221125_WJC_METTL3_EV_vs_WT_F03.18779.18779.3 5.79E-05 13/40 R.VHIGQVIMSIR[166.11].T "sp|P27635|RL10_HUMAN,sp|Q96L21|RL10L_HUMAN,tr|H7C123|H7C123_HUMAN,tr|H7C2C5|H7C2C5_HUMAN,tr|F8W7C6|F8W7C6_HUMAN,tr|X1WI28|X1WI28_HUMAN" 6 1261.7204 0.91 33856 18779 3 1261.718102 421.5808 60S ribosomal protein L10 OS=Homo sapiens OX=9606 GN=RPL10 PE=1 SV=4 9.73 3178.1 - 1.80E+06 - - - -1.8467 - 2.683 0.506 - 297.2 1 2 0 -0.0023 11 0 0 0 5.40E+07 5.93E+07 - - - 6.9845 1 221125_WJC_METTL3_EV_vs_WT_F03.18782.18782.3 0.000414 Nov-40 R.VHIGQVIMSIR.T "sp|P27635|RL10_HUMAN,sp|Q96L21|RL10L_HUMAN,tr|H7C123|H7C123_HUMAN,tr|H7C2C5|H7C2C5_HUMAN,tr|F8W7C6|F8W7C6_HUMAN,tr|X1WI28|X1WI28_HUMAN" 6 1251.7122 0.91 33859 18782 3 1251.7105 418.2447 60S ribosomal protein L10 OS=Homo sapiens OX=9606 GN=RPL10 PE=1 SV=4 9.73 3178.4 - 1.32E+06 - - - -1.3278 - 2.433 0.507 - 232.3 1 2 0 -0.0017 11 0 0 0 5.38E+07 5.91E+07 - - - 6.7179 0.9999 221125_WJC_METTL3_EV_vs_WT_F03.18783.18783.2 5.22E-07 26-Nov R.VLNSYWVGEDSTYK[136.11].F "sp|P61313|RL15_HUMAN,tr|A0A2R8YEM3|A0A2R8YEM3_HUMAN,tr|A0A2R8Y738|A0A2R8Y738_HUMAN,tr|E7EQV9|E7EQV9_HUMAN,tr|E7EX53|E7EX53_HUMAN,tr|E7ENU7|E7ENU7_HUMAN" 6 1667.7923 0.88 33860 18783 2 1667.790435 834.9034 60S ribosomal protein L15 OS=Homo sapiens OX=9606 GN=RPL15 PE=1 SV=2 4.37 3178.5 - 1.25E+06 - - - -1.0901 - 2.267 0.546 - 334.8 1 2 0 -0.0018 14 0 0 0 5.21E+06 5.94E+06 - - - 5.1271 0.9218 221125_WJC_METTL3_EV_vs_WT_F03.18784.18784.2 0.0302 30-Oct K.GSLGGGFSSGGFSGGS.F "sp|P13645|K1C10_HUMAN,tr|A0A1B0GVI3|A0A1B0GVI3_HUMAN" 2 1316.5633 - 33861 18784 2 1316.561678 659.2889 "Keratin, type I cytoskeletal 10 OS=Homo sapiens OX=9606 GN=KRT10 PE=1 SV=6" 5.52 3178.6 - 1.23E+06 - - - -1.2388 - 1.69 0.27 - 196.8 1 1 0 -0.0016 16 0 0 0 - - - - - 2.3248 1 221125_WJC_METTL3_EV_vs_WT_F03.18788.18788.3 2.60E-11 19/56 R.MGPLGLDHMASSIER[166.11].M "sp|P52272|HNRPM_HUMAN,tr|A0A087X0X3|A0A087X0X3_HUMAN,tr|M0QZM1|M0QZM1_HUMAN" 3 1622.7784 1.62 33864 18788 3 1622.777532 541.9334 Heterogeneous nuclear ribonucleoprotein M OS=Homo sapiens OX=9606 GN=HNRNPM PE=1 SV=3 5.3 3178.9 - 1.21E+07 - - - -0.5454 - 3.609 0.646 - 662.8 1 2 0 -0.0009 15 0 0 0 4.49E+08 2.76E+08 - - - 9.091 0.9998 221125_WJC_METTL3_EV_vs_WT_F03.18789.18789.2 0.000682 13/18 K.LNIGDLQVTK[136.11].E "sp|Q9UNM6|PSD13_HUMAN,tr|J3KNQ3|J3KNQ3_HUMAN,tr|E9PL38|E9PL38_HUMAN,tr|H0YD73|H0YD73_HUMAN,tr|A0A087WUL9|A0A087WUL9_HUMAN" 5 1107.6379 0.65 33865 18789 2 1107.637667 554.8262 26S proteasome non-ATPase regulatory subunit 13 OS=Homo sapiens OX=9606 GN=PSMD13 PE=1 SV=2 5.84 3179 - 4.63E+06 - - - -0.232 - 2.491 0.367 - 475.9 1 2 0 -0.0003 10 0 0 0 1.57E+07 2.41E+07 - - - 4.2992 0.9997 221125_WJC_METTL3_EV_vs_WT_F03.18790.18790.3 0.000732 Dec-44 R.NQYVTLHDMILK.N "sp|P61289|PSME3_HUMAN,tr|B3KQ25|B3KQ25_HUMAN,tr|K7ESG5|K7ESG5_HUMAN,tr|K9J957|K9J957_HUMAN,tr|A0A087WTV2|A0A087WTV2_HUMAN" 5 1473.765 1.13 33866 18790 3 1473.764176 492.2623 Proteasome activator complex subunit 3 OS=Homo sapiens OX=9606 GN=PSME3 PE=1 SV=1 6.74 3179.1 - 4.58E+06 - - - -0.5489 - 2.276 0.303 - 259.6 1 2 0 -0.0008 12 0 0 0 1.49E+07 1.32E+07 - - - 4.1976 0.882 221125_WJC_METTL3_EV_vs_WT_F03.18795.18795.2 0.434 16-Jul Q.LSVQEDVKI.- sp|P36896|ACV1B_HUMAN 1 1029.5706 999 33871 18795 2 1029.5706 515.7926 Activin receptor type-1B OS=Homo sapiens OX=9606 GN=ACVR1B PE=1 SV=1 4.37 3179.5 - 1.70E+06 - - - -0.0253 - 1.548 0.226 - 118.2 4 1 0 0 9 0 0 0 9.43E+06 0.00E+00 - - - 1.7054 1 221125_WJC_METTL3_EV_vs_WT_F03.18796.18796.2 8.01E-10 17/26 R.VLNSYWVGEDSTYK.F "sp|P61313|RL15_HUMAN,tr|A0A2R8YEM3|A0A2R8YEM3_HUMAN,tr|A0A2R8Y738|A0A2R8Y738_HUMAN,tr|E7EQV9|E7EQV9_HUMAN,tr|E7EX53|E7EX53_HUMAN,tr|E7ENU7|E7ENU7_HUMAN" 6 1659.7781 -1 33872 18796 2 1659.770277 830.8963 60S ribosomal protein L15 OS=Homo sapiens OX=9606 GN=RPL15 PE=1 SV=2 4.37 3179.6 - 1.61E+06 - - - -4.685 - 3.17 0.595 - 1047.3 1 2 0 -0.0078 14 0 0 0 0.00E+00 0.00E+00 - - - 6.3285 0.9943 221125_WJC_METTL3_EV_vs_WT_F03.18798.18798.3 1.55 Nov-52 K.ALGDQILFVNRPDK.K "sp|P29084|T2EB_HUMAN,tr|E5RH41|E5RH41_HUMAN" 2 1584.8624 1.01 33874 18798 3 1584.86277 529.2947 Transcription initiation factor IIE subunit beta OS=Homo sapiens OX=9606 GN=GTF2E2 PE=1 SV=1 6 3179.8 - 1.56E+06 - - - 0.2391 - 2.035 0.155 - 144.2 1 2 0 0.0004 14 0 0 0 7.10E+06 7.05E+06 - - - 2.1562 0.9248 221125_WJC_METTL3_EV_vs_WT_F03.18800.18800.2 9.90E-05 20-Nov R.LWDLTTGTTTR[166.11].R "sp|P63244|RACK1_HUMAN,tr|D6RFX4|D6RFX4_HUMAN,tr|D6RFZ9|D6RFZ9_HUMAN,tr|D6RAU2|D6RAU2_HUMAN,tr|H0YAF8|H0YAF8_HUMAN,tr|D6R9Z1|D6R9Z1_HUMAN,tr|J3KPE3|J3KPE3_HUMAN,tr|D6R9L0|D6R9L0_HUMAN,tr|D6RHH4|D6RHH4_HUMAN,tr|E9PD14|E9PD14_HUMAN,tr|H0Y8W2|H0Y8W2_HUMAN" 11 1273.6542 1.16 33876 18800 2 1273.644921 637.8344 Receptor of activated protein C kinase 1 OS=Homo sapiens OX=9606 GN=RACK1 PE=1 SV=3 5.84 3180.1 - 1.30E+06 - - - -7.2743 - 2.161 0.181 - 428.2 1 2 0 -0.0093 11 0 0 0 1.20E+07 1.03E+07 - - - 2.4595 0.9999 221125_WJC_METTL3_EV_vs_WT_F03.18801.18801.2 1.62E-05 26-Dec K.QGGPTYYIDTNALR.V "sp|O96019|ACL6A_HUMAN,tr|C9JQT2|C9JQT2_HUMAN,tr|H7C5S0|H7C5S0_HUMAN" 3 1567.7631 0.84 33877 18801 2 1567.761992 784.8888 Actin-like protein 6A OS=Homo sapiens OX=9606 GN=ACTL6A PE=1 SV=1 5.83 3180.2 - 1.30E+06 - - - -0.6882 - 2.63 0.541 - 449.6 1 2 0 -0.0011 14 0 0 0 6.92E+06 8.22E+06 - - - 5.4631 1 221125_WJC_METTL3_EV_vs_WT_F03.18807.18807.3 1.38E-07 18/56 R.MGPLGLDHMASSIER.M "sp|P52272|HNRPM_HUMAN,tr|A0A087X0X3|A0A087X0X3_HUMAN,tr|M0QZM1|M0QZM1_HUMAN" 3 1612.7701 1.61 33882 18807 3 1612.770418 538.5973 Heterogeneous nuclear ribonucleoprotein M OS=Homo sapiens OX=9606 GN=HNRNPM PE=1 SV=3 5.3 3180.9 - 4.02E+07 - - - 0.168 - 3.755 0.621 - 610.4 1 2 0 0.0003 15 0 0 0 4.46E+08 2.76E+08 - - - 8.9159 1 221125_WJC_METTL3_EV_vs_WT_F03.18811.18811.2 4.29E-13 20/28 R.MGPLGLDHMASSIER.M "sp|P52272|HNRPM_HUMAN,tr|A0A087X0X3|A0A087X0X3_HUMAN,tr|M0QZM1|M0QZM1_HUMAN" 3 1612.7701 2.22 33886 18811 2 1612.763498 807.3923 Heterogeneous nuclear ribonucleoprotein M OS=Homo sapiens OX=9606 GN=HNRNPM PE=1 SV=3 5.3 3181.1 - 2.14E+06 - - - -4.1227 - 3.509 0.681 - 1587.8 1 2 0 -0.0066 15 0 0 0 2.69E+07 1.22E+07 - - - 7.1551 0.9999 221125_WJC_METTL3_EV_vs_WT_F03.18812.18812.2 0.0033 15/24 K.SNILLLGPTGSGK.T sp|O76031|CLPX_HUMAN 1 1255.7136 0.83 33887 18812 2 1255.713051 628.8641 "ATP-dependent Clp protease ATP-binding subunit clpX-like, mitochondrial OS=Homo sapiens OX=9606 GN=CLPX PE=1 SV=2" 8.47 3181.3 - 1.77E+06 - - - -0.4388 - 2.727 0.395 - 776.3 1 2 0 -0.0006 13 0 0 0 1.03E+07 1.24E+07 - - - 4.533 0.9999 221125_WJC_METTL3_EV_vs_WT_F03.18813.18813.2 1.19E-09 14/28 K.ILFVSQGSEIASQGR[166.11].E "sp|Q9NUQ7|UFSP2_HUMAN,tr|H0Y9B0|H0Y9B0_HUMAN,tr|H0YA18|H0YA18_HUMAN" 3 1600.8448 1.22 33888 18813 2 1600.84615 801.4297 Ufm1-specific protease 2 OS=Homo sapiens OX=9606 GN=UFSP2 PE=1 SV=3 6 3181.4 - 1.65E+06 - - - 0.8183 - 2.767 0.491 - 616.6 1 2 0 0.0013 15 0 0 0 1.60E+07 1.31E+07 - - - 5.1693 0.9997 221125_WJC_METTL3_EV_vs_WT_F03.18816.18816.2 0.00335 20-Nov R.LWDLTTGTTTR.R "sp|P63244|RACK1_HUMAN,tr|D6RFX4|D6RFX4_HUMAN,tr|D6RFZ9|D6RFZ9_HUMAN,tr|D6RAU2|D6RAU2_HUMAN,tr|H0YAF8|H0YAF8_HUMAN,tr|D6R9Z1|D6R9Z1_HUMAN,tr|J3KPE3|J3KPE3_HUMAN,tr|D6R9L0|D6R9L0_HUMAN,tr|D6RHH4|D6RHH4_HUMAN,tr|E9PD14|E9PD14_HUMAN,tr|H0Y8W2|H0Y8W2_HUMAN" 11 1263.6459 1.16 33891 18816 2 1263.646777 632.8302 Receptor of activated protein C kinase 1 OS=Homo sapiens OX=9606 GN=RACK1 PE=1 SV=3 5.84 3181.6 - 1.34E+06 - - - 0.6814 - 1.856 0.433 - 364.9 1 2 0 0.0009 11 0 0 0 1.20E+07 1.03E+07 - - - 3.9118 0.9974 221125_WJC_METTL3_EV_vs_WT_F03.18818.18818.3 0.03 Oct-32 K.DK[136.11]PLAEWLR[166.11].K sp|O00443|P3C2A_HUMAN 1 1144.636 0.001 33893 18818 3 1144.635189 382.5526 Phosphatidylinositol 4-phosphate 3-kinase C2 domain-containing subunit alpha OS=Homo sapiens OX=9606 GN=PIK3C2A PE=1 SV=2 6.07 3181.9 - 1.18E+06 - - - -0.6771 - 1.703 0.225 - 177.6 1 2 0 -0.0008 9 0 0 0 0.00E+00 5.98E+06 - - - 2.6528 0.908 221125_WJC_METTL3_EV_vs_WT_F03.18822.18822.3 3.08 13/52 K.ALGDQILFVNR[166.11]PDK[136.11].K "sp|P29084|T2EB_HUMAN,tr|E5RH41|E5RH41_HUMAN" 2 1602.8849 1.34 33897 18822 3 1602.890059 535.3022 Transcription initiation factor IIE subunit beta OS=Homo sapiens OX=9606 GN=GTF2E2 PE=1 SV=1 6 3182.4 - 904481 - - - 3.2429 - 2.082 0.077 - 188.9 1 2 0 0.0052 14 0 0 0 6.72E+06 5.01E+06 - - - 1.3459 1 221125_WJC_METTL3_EV_vs_WT_F03.18823.18823.2 8.56E-08 16/24 R.DVIDEPIIEEPSR.L sp|O60216|RAD21_HUMAN 1 1510.7515 0.95 33898 18823 2 1510.754485 756.383 Double-strand-break repair protein rad21 homolog OS=Homo sapiens OX=9606 GN=RAD21 PE=1 SV=2 3.83 3182.5 - 872150 - - - 1.9739 - 2.938 0.544 - 921.4 1 2 0 0.003 13 0 0 0 1.17E+07 1.24E+07 - - - 5.8241 0.9991 221125_WJC_METTL3_EV_vs_WT_F03.18828.18828.2 0.000254 20-Nov K.QLEDELVSLQK.K "sp|P09493|TPM1_HUMAN,tr|A0A0S2Z4G6|A0A0S2Z4G6_HUMAN,tr|H0YKP3|H0YKP3_HUMAN,tr|A0A087WTJ7|A0A087WTJ7_HUMAN" 4 1300.6874 -1 33902 18828 2 1300.690437 651.351 Tropomyosin alpha-1 chain OS=Homo sapiens OX=9606 GN=TPM1 PE=1 SV=2 4.14 3183.1 - 1.68E+06 - - - 2.2988 - 1.936 0.367 - 375.8 1 2 0 0.003 11 0 0 0 0.00E+00 0.00E+00 - - - 3.5379 1 221125_WJC_METTL3_EV_vs_WT_F03.18829.18829.2 2.17E-08 14/30 K.LMQGFNEDMAIEAQQK[136.11].F sp|O14929|HAT1_HUMAN 1 1859.8637 -1 33903 18829 2 1859.853045 930.9391 Histone acetyltransferase type B catalytic subunit OS=Homo sapiens OX=9606 GN=HAT1 PE=1 SV=1 4.14 3183.2 - 529422 - - - -5.7397 - 2.884 0.638 - 731.3 1 2 0 -0.0107 16 0 0 0 0.00E+00 0.00E+00 - - - 6.354 0.9999 221125_WJC_METTL3_EV_vs_WT_F03.18832.18832.2 5.61E-06 28-Dec K.ILFVSQGSEIASQGR.E "sp|Q9NUQ7|UFSP2_HUMAN,tr|H0Y9B0|H0Y9B0_HUMAN,tr|H0YA18|H0YA18_HUMAN" 3 1590.8366 1.22 33906 18832 2 1590.837396 796.4256 Ufm1-specific protease 2 OS=Homo sapiens OX=9606 GN=UFSP2 PE=1 SV=3 6 3183.4 - 3.20E+06 - - - 0.5192 - 2.662 0.529 - 451.5 1 2 0 0.0008 15 0 0 0 1.60E+07 1.31E+07 - - - 5.355 1 221125_WJC_METTL3_EV_vs_WT_F03.18834.18834.2 4.38E-08 15/28 S.YLLAALGGNSSPSAK.D sp|P05387|RLA2_HUMAN 1 1447.7671 1.28 33908 18834 2 1447.767412 724.8908 60S acidic ribosomal protein P2 OS=Homo sapiens OX=9606 GN=RPLP2 PE=1 SV=1 8.59 3183.5 - 2.42E+06 - - - 0.2196 - 2.892 0.561 - 723.4 1 1 0 0.0003 15 0 0 0 3.64E+07 2.85E+07 - - - 5.7953 0.9914 221125_WJC_METTL3_EV_vs_WT_F03.18835.18835.2 0.00045 28-Dec S.YLLAALGGNSSPSAK[136.11].D sp|P05387|RLA2_HUMAN 1 1455.7813 1.25 33909 18835 2 1455.782912 728.8979 60S acidic ribosomal protein P2 OS=Homo sapiens OX=9606 GN=RPLP2 PE=1 SV=1 8.59 3183.6 - 2.32E+06 - - - 1.1114 - 2.51 0.521 - 404.7 1 1 0 0.0016 15 0 0 0 3.64E+07 2.91E+07 - - - 5.1512 0.9999 221125_WJC_METTL3_EV_vs_WT_F03.18837.18837.2 6.23E-05 20-Dec R.NELESYAYSLK.N "sp|P11021|BIP_HUMAN,tr|A0A7P0TB36|A0A7P0TB36_HUMAN,tr|A0A7P0TAI0|A0A7P0TAI0_HUMAN" 3 1315.6296 0.54 33911 18837 2 1315.630337 658.8221 Endoplasmic reticulum chaperone BiP OS=Homo sapiens OX=9606 GN=HSPA5 PE=1 SV=2 4.53 3183.7 - 2.04E+06 - - - 0.5625 - 2.237 0.532 - 663.8 1 2 0 0.0007 11 0 0 0 2.26E+07 4.15E+07 - - - 5.1482 0.9998 221125_WJC_METTL3_EV_vs_WT_F03.18838.18838.2 0.000193 22-Nov K.EQADFAVEALAK[136.11].A "sp|P35580|MYH10_HUMAN,sp|P35749|MYH11_HUMAN,tr|A0A494C024|A0A494C024_HUMAN" 3 1298.6598 1.15 33912 18838 2 1298.661935 650.3372 Myosin-10 OS=Homo sapiens OX=9606 GN=MYH10 PE=1 SV=3 4.14 3183.8 - 1.89E+06 - - - 1.6579 - 2.179 0.525 - 417.8 1 2 0 0.0022 12 0 0 0 2.50E+07 2.18E+07 - - - 4.9673 0.9999 221125_WJC_METTL3_EV_vs_WT_F03.18839.18839.2 1.09E-05 22-Dec K.EQADFAVEALAK.A "sp|P35580|MYH10_HUMAN,sp|P35749|MYH11_HUMAN,tr|A0A494C024|A0A494C024_HUMAN" 3 1290.6456 0.55 33913 18839 2 1290.646637 646.3301 Myosin-10 OS=Homo sapiens OX=9606 GN=MYH10 PE=1 SV=3 4.14 3183.9 - 1.76E+06 - - - 0.8174 - 2.324 0.508 - 482.9 1 2 0 0.0011 12 0 0 0 3.19E+07 5.76E+07 - - - 5.0116 0.9999 221125_WJC_METTL3_EV_vs_WT_F03.18843.18843.3 0.000457 13/44 K.MALDIEIATYR[166.11]K[136.11].L "sp|P08670|VIME_HUMAN,sp|P41219|PERI_HUMAN,tr|H7C5W5|H7C5W5_HUMAN,tr|B0YJC5|B0YJC5_HUMAN,tr|B0YJC4|B0YJC4_HUMAN" 5 1440.7766 0.16 33917 18843 3 1440.77558 481.2661 Vimentin OS=Homo sapiens OX=9606 GN=VIM PE=1 SV=4 5.82 3184.2 - 829967 - - - -0.6774 - 2.514 0.361 - 253.2 1 2 0 -0.001 12 0 0 0 3.11E+06 1.95E+07 - - - 5.1198 0.9981 221125_WJC_METTL3_EV_vs_WT_F03.18844.18844.3 0.00438 Nov-56 K.ILFVSQGSEIASQGR[166.11].E "sp|Q9NUQ7|UFSP2_HUMAN,tr|H0Y9B0|H0Y9B0_HUMAN,tr|H0YA18|H0YA18_HUMAN" 3 1600.8448 2.99 33918 18844 3 1600.843787 534.6222 Ufm1-specific protease 2 OS=Homo sapiens OX=9606 GN=UFSP2 PE=1 SV=3 6 3184.3 - 740911 - - - -0.6578 - 2.268 0.195 - 163.9 1 2 0 -0.0011 15 0 0 0 1.16E+07 3.88E+06 - - - 2.8506 0.9984 221125_WJC_METTL3_EV_vs_WT_F03.18845.18845.3 0.0019 Nov-44 R.DLKPENLLLASK.C "sp|Q13554|KCC2B_HUMAN,sp|Q9UQM7|KCC2A_HUMAN,sp|Q13555|KCC2G_HUMAN,sp|Q13557|KCC2D_HUMAN,tr|A0A5F9ZH21|A0A5F9ZH21_HUMAN,tr|E9PBG7|E9PBG7_HUMAN,tr|E7EQE4|E7EQE4_HUMAN,tr|A0A2Q3DQE3|A0A2Q3DQE3_HUMAN,tr|H7BXS4|H7BXS4_HUMAN,tr|A0A5F9ZHY2|A0A5F9ZHY2_HUMAN,tr|H0Y6G2|H0Y6G2_HUMAN,tr|A0A5K1VW76|A0A5K1VW76_HUMAN,tr|A0A5F9ZHR5|A0A5F9ZHR5_HUMAN,tr|D6R938|D6R938_HUMAN,tr|Q8WU40|Q8WU40_HUMAN,tr|E9PF82|E9PF82_HUMAN,tr|A0A804HIC9|A0A804HIC9_HUMAN,tr|A0A5F9ZH50|A0A5F9ZH50_HUMAN,tr|A0A5F9ZHM9|A0A5F9ZHM9_HUMAN,tr|D6RFJ0|D6RFJ0_HUMAN,tr|E9PBE8|E9PBE8_HUMAN,tr|Q5SWX3|Q5SWX3_HUMAN" 22 1339.7711 0.37 33919 18845 3 1339.770573 447.5976 Calcium\calmodulin-dependent protein kinase type II subunit beta OS=Homo sapiens OX=9606 GN=CAMK2B PE=1 SV=3 6.07 3184.4 - 596830 - - - -0.406 - 1.991 0.229 - 209.9 1 2 0 -0.0005 12 0 0 0 4.79E+06 1.30E+07 - - - 3.0018 0.9995 221125_WJC_METTL3_EV_vs_WT_F03.18847.18847.2 0.00398 30-Sep K.EAQAVPATLPELEATK.A "sp|Q15149|PLEC_HUMAN,tr|H0YDN1|H0YDN1_HUMAN" 2 1666.8778 3.17 33921 18847 2 1666.876046 834.4462 Plectin OS=Homo sapiens OX=9606 GN=PLEC PE=1 SV=3 4.25 3184.7 - 520865 - - - -1.0325 - 1.874 0.347 - 174.1 1 2 0 -0.0017 16 0 0 0 4.30E+06 1.36E+06 - - - 3.1476 1 221125_WJC_METTL3_EV_vs_WT_F03.18849.18849.2 8.39E-08 30-Nov K.LMQGFNEDMAIEAQQK.F sp|O14929|HAT1_HUMAN 1 1851.8495 1.12 33922 18849 2 1851.854615 926.932 Histone acetyltransferase type B catalytic subunit OS=Homo sapiens OX=9606 GN=HAT1 PE=1 SV=1 4.14 3184.9 - 372339 - - - 2.7513 - 2.388 0.662 - 394.1 1 2 0 0.0051 16 0 0 0 2.08E+06 1.86E+06 - - - 6.069 0.9998 221125_WJC_METTL3_EV_vs_WT_F03.18852.18852.2 3.82E-06 20-Nov R.VHIGQVIMSIR[166.11].T "sp|P27635|RL10_HUMAN,sp|Q96L21|RL10L_HUMAN,tr|H7C123|H7C123_HUMAN,tr|H7C2C5|H7C2C5_HUMAN,tr|F8W7C6|F8W7C6_HUMAN,tr|X1WI28|X1WI28_HUMAN" 6 1261.7204 0.88 33925 18852 2 1261.720858 631.8675 60S ribosomal protein L10 OS=Homo sapiens OX=9606 GN=RPL10 PE=1 SV=4 9.73 3185.1 - 2.08E+06 - - - 0.3376 - 1.904 0.504 - 357.9 1 2 0 0.0004 11 0 0 0 2.97E+07 3.38E+07 - - - 4.5055 0.9998 221125_WJC_METTL3_EV_vs_WT_F03.18854.18854.2 0.000194 20-Dec R.VHIGQVIMSIR.T "sp|P27635|RL10_HUMAN,sp|Q96L21|RL10L_HUMAN,tr|H7C123|H7C123_HUMAN,tr|H7C2C5|H7C2C5_HUMAN,tr|F8W7C6|F8W7C6_HUMAN,tr|X1WI28|X1WI28_HUMAN" 6 1251.7122 0.88 33927 18854 2 1251.713143 626.8634 60S ribosomal protein L10 OS=Homo sapiens OX=9606 GN=RPL10 PE=1 SV=4 9.73 3185.3 - 1.88E+06 - - - 0.7837 - 2.235 0.479 - 435.4 1 2 0 0.001 11 0 0 0 2.97E+07 3.38E+07 - - - 4.7542 1 221125_WJC_METTL3_EV_vs_WT_F03.18855.18855.3 5.07E-07 18/56 K.IPDHDPAPNVTVLLR.E "sp|Q9P2E9|RRBP1_HUMAN,tr|A2A2S5|A2A2S5_HUMAN" 2 1655.8995 0.96 33928 18855 3 1655.903585 552.9738 Ribosome-binding protein 1 OS=Homo sapiens OX=9606 GN=RRBP1 PE=1 SV=5 5.21 3185.4 - 1.73E+06 - - - 2.4639 - 3.085 0.6 - 501.1 1 2 0 0.0041 15 0 0 0 2.19E+07 2.28E+07 - - - 8.1679 0.9999 221125_WJC_METTL3_EV_vs_WT_F03.18857.18857.2 2.95E-05 18-Nov R.TISLC[160.03]C[160.03]WDSR[166.11].T sp|Q05048|CSTF1_HUMAN 1 1306.5674 0.71 33930 18857 2 1306.567583 654.291 Cleavage stimulation factor subunit 1 OS=Homo sapiens OX=9606 GN=CSTF1 PE=1 SV=1 5.5 3185.6 - 776419 - - - 0.1691 - 1.938 0.515 - 390.3 1 2 0 0.0002 10 0 0 0 2.39E+06 3.35E+06 - - - 4.6916 1 221125_WJC_METTL3_EV_vs_WT_F03.18860.18860.2 4.82E-07 19/26 M.GPLGLDHMASSIER.M "sp|P52272|HNRPM_HUMAN,tr|A0A087X0X3|A0A087X0X3_HUMAN,tr|M0QZM1|M0QZM1_HUMAN" 3 1481.7297 -1 33933 18860 2 1481.719363 741.8721 Heterogeneous nuclear ribonucleoprotein M OS=Homo sapiens OX=9606 GN=HNRNPM PE=1 SV=3 5.32 3186 - 467756 - - - -6.9513 - 3.459 0.605 - 1595.3 1 1 0 -0.0103 14 0 0 0 0.00E+00 0.00E+00 - - - 6.6205 0.996 221125_WJC_METTL3_EV_vs_WT_F03.18862.18862.3 0.003 14/36 R.STLVLHDLLK[136.11].H "sp|P11274|BCR_HUMAN,sp|Q12979|ABR_HUMAN,tr|B7Z683|B7Z683_HUMAN,tr|A0A0G2JQ41|A0A0G2JQ41_HUMAN,tr|A0A1C7CYZ0|A0A1C7CYZ0_HUMAN,tr|H0Y554|H0Y554_HUMAN,tr|I3L2P5|I3L2P5_HUMAN,tr|I3L1U8|I3L1U8_HUMAN,tr|I3L4Y1|I3L4Y1_HUMAN" 9 1145.69 1.08 33935 18862 3 1145.689262 382.9039 Breakpoint cluster region protein OS=Homo sapiens OX=9606 GN=BCR PE=1 SV=2 6.46 3186.3 - 618275 - - - -0.6092 - 2.02 0.16 - 253.7 1 2 0 -0.0007 10 0 0 0 2.18E+06 2.02E+06 - - - 2.377 0.9997 221125_WJC_METTL3_EV_vs_WT_F03.18863.18863.3 0.0857 Dec-40 K.K[136.11]GVTSILPVLR[166.11].E sp|Q92616|GCN1_HUMAN 1 1199.7721 0.56 33936 18863 3 1199.772491 400.9313 eIF-2-alpha kinase activator GCN1 OS=Homo sapiens OX=9606 GN=GCN1 PE=1 SV=6 11 3186.4 - 386382 - - - 0.3567 - 1.99 0.342 - 145.3 1 2 0 0.0004 11 0 0 0 2.69E+06 4.77E+06 - - - 4.3077 1 221125_WJC_METTL3_EV_vs_WT_F03.18867.18867.3 6.59E-07 19/44 R.LPVDLAEELGHR.D "sp|P42771|CDN2A_HUMAN,tr|K7ENC6|K7ENC6_HUMAN,tr|J3QRG6|J3QRG6_HUMAN,tr|K7ES20|K7ES20_HUMAN" 4 1347.7147 1.47 33939 18867 3 1347.714099 450.2455 Cyclin-dependent kinase inhibitor 2A OS=Homo sapiens OX=9606 GN=CDKN2A PE=1 SV=2 4.65 3186.9 - 4.21E+06 - - - -0.4192 - 3.233 0.524 - 673.2 1 2 0 -0.0006 12 0 0 0 2.59E+08 1.76E+08 - - - 7.6344 1 221125_WJC_METTL3_EV_vs_WT_F03.18869.18869.3 1.67E-08 18/44 R.LPVDLAEELGHR[166.11].D "sp|P42771|CDN2A_HUMAN,tr|K7ENC6|K7ENC6_HUMAN,tr|J3QRG6|J3QRG6_HUMAN,tr|K7ES20|K7ES20_HUMAN" 4 1357.7229 1.47 33941 18869 3 1357.722734 453.5816 Cyclin-dependent kinase inhibitor 2A OS=Homo sapiens OX=9606 GN=CDKN2A PE=1 SV=2 4.65 3186.9 - 2.23E+06 - - - -0.1473 - 3.208 0.568 - 629.6 1 2 0 -0.0002 12 0 0 0 2.59E+08 1.76E+08 - - - 8.1036 1 221125_WJC_METTL3_EV_vs_WT_F03.18870.18870.3 2.34E-06 13/56 K.IPDHDPAPNVTVLLR[166.11].E "sp|Q9P2E9|RRBP1_HUMAN,tr|A2A2S5|A2A2S5_HUMAN" 2 1665.9078 1.02 33942 18870 3 1665.905467 556.3099 Ribosome-binding protein 1 OS=Homo sapiens OX=9606 GN=RRBP1 PE=1 SV=5 5.21 3187 - 2.17E+06 - - - -1.3854 - 2.569 0.573 - 208.3 1 2 0 -0.0023 15 0 0 0 3.45E+07 3.37E+07 - - - 7.3897 0.999 221125_WJC_METTL3_EV_vs_WT_F03.18874.18874.3 5.49E-05 14/40 K.SFLYEIVSNK[136.11]R[166.11].N "sp|Q9Y3Z3|SAMH1_HUMAN,tr|A0A2R8YD90|A0A2R8YD90_HUMAN,tr|A0A2R8YCS7|A0A2R8YCS7_HUMAN" 3 1372.747 3.66 33946 18874 3 1372.744246 458.5896 Deoxynucleoside triphosphate triphosphohydrolase SAMHD1 OS=Homo sapiens OX=9606 GN=SAMHD1 PE=1 SV=2 8.31 3187.3 - 1.21E+06 - - - -1.9851 - 2.365 0.247 - 271.5 1 2 0 -0.0027 11 0 0 0 1.13E+08 3.09E+07 - - - 3.7384 1 221125_WJC_METTL3_EV_vs_WT_F03.18875.18875.3 5.11E-08 14/52 R.EDSQYLELATLEHR.M "sp|Q96ER9|MITOK_HUMAN,tr|C9JSW8|C9JSW8_HUMAN" 2 1702.8162 1.76 33947 18875 3 1702.816547 568.6127 Mitochondrial potassium channel OS=Homo sapiens OX=9606 GN=CCDC51 PE=1 SV=2 4.4 3187.4 - 924096 - - - 0.1867 - 2.762 0.562 - 306.4 1 2 0 0.0003 14 0 0 0 6.04E+06 3.44E+06 - - - 7.5056 1 221125_WJC_METTL3_EV_vs_WT_F03.18876.18876.3 2.99E-05 13/36 R.YFSVIEDLKR.Q sp|Q7Z3Y9|K1C26_HUMAN 1 1268.6765 58.97 33948 18876 3 1268.675034 423.8994 "Keratin, type I cytoskeletal 26 OS=Homo sapiens OX=9606 GN=KRT26 PE=1 SV=2" 6.07 3187.5 - 839449 - - - -1.1461 - 2.592 0.51 - 212.7 1 2 0 -0.0015 10 0 0 0 6.82E+06 1.16E+05 - - - 7.0071 1 221125_WJC_METTL3_EV_vs_WT_F03.18878.18878.3 8.15E-08 18/52 R.EDSQYLELATLEHR[166.11].M "sp|Q96ER9|MITOK_HUMAN,tr|C9JSW8|C9JSW8_HUMAN" 2 1712.8245 1.76 33950 18878 3 1712.822334 571.9488 Mitochondrial potassium channel OS=Homo sapiens OX=9606 GN=CCDC51 PE=1 SV=2 4.4 3187.8 - 663899 - - - -1.264 - 3.129 0.536 - 519.9 1 2 0 -0.0022 14 0 0 0 6.04E+06 3.44E+06 - - - 7.5468 0.9992 221125_WJC_METTL3_EV_vs_WT_F03.18879.18879.2 0.00295 18-Sep R.DMDDEESWIK.E "sp|Q13813|SPTN1_HUMAN,tr|A0A0D9SF54|A0A0D9SF54_HUMAN,tr|A0A0D9SGF6|A0A0D9SGF6_HUMAN" 3 1266.5074 0.69 33951 18879 2 1266.506508 634.261 "Spectrin alpha chain, non-erythrocytic 1 OS=Homo sapiens OX=9606 GN=SPTAN1 PE=1 SV=3" 3.77 3187.9 - 506252 - - - -0.7304 - 1.166 0.426 - 176.9 1 2 0 -0.0009 10 0 0 0 3.47E+06 5.07E+06 - - - 2.6158 0.9999 221125_WJC_METTL3_EV_vs_WT_F03.18880.18880.2 9.96E-08 24-Oct R.DMGGYSTTTDFIK[136.11].S "sp|O43837|IDH3B_HUMAN,tr|A0A087WZN1|A0A087WZN1_HUMAN,tr|A0A0D9SG66|A0A0D9SG66_HUMAN" 3 1442.6479 2.02 33952 18880 2 1442.648149 722.3312 "Isocitrate dehydrogenase [NAD] subunit beta, mitochondrial OS=Homo sapiens OX=9606 GN=IDH3B PE=1 SV=2" 4.21 3188.1 - 417666 - - - 0.1754 - 2.122 0.618 - 221.6 1 2 0 0.0003 13 0 0 0 6.27E+06 3.10E+06 - - - 5.5364 0.9985 221125_WJC_METTL3_EV_vs_WT_F03.18881.18881.3 0.00351 Oct-44 R.GK[136.11]DLIGVQNLLK[136.11].K "sp|Q13813|SPTN1_HUMAN,tr|A0A0D9SF54|A0A0D9SF54_HUMAN,tr|A0A0D9SGF6|A0A0D9SGF6_HUMAN" 3 1312.8049 1.33 33953 18881 3 1312.805357 438.6089 "Spectrin alpha chain, non-erythrocytic 1 OS=Homo sapiens OX=9606 GN=SPTAN1 PE=1 SV=3" 8.59 3188.2 - 411178 - - - 0.3207 - 2.061 0.326 - 145.3 1 2 1 0.0004 12 0 0 0 3.00E+06 2.25E+06 - - - 4.179 0.9999 221125_WJC_METTL3_EV_vs_WT_F03.18884.18884.3 3.26E-06 Oct-40 K.MTPPIKDLLPR.L "sp|O75533|SF3B1_HUMAN,tr|H7C341|H7C341_HUMAN" 2 1279.7322 1.75 33956 18884 3 1279.731918 427.5847 Splicing factor 3B subunit 1 OS=Homo sapiens OX=9606 GN=SF3B1 PE=1 SV=3 8.5 3188.6 - 268453 - - - -0.243 - 2.243 0.517 - 170.6 1 2 1 -0.0003 11 0 0 0 9.01E+06 5.14E+06 - - - 6.5988 1 221125_WJC_METTL3_EV_vs_WT_F03.18888.18888.3 0.000735 15/52 R.YEDFSNLGTTHLLR.L "sp|P22695|QCR2_HUMAN,tr|H3BP04|H3BP04_HUMAN,tr|H3BUE4|H3BUE4_HUMAN,tr|H3BUI9|H3BUI9_HUMAN,tr|H3BRG4|H3BRG4_HUMAN,tr|H3BSJ9|H3BSJ9_HUMAN,tr|A0A087WVZ4|A0A087WVZ4_HUMAN" 7 1664.8158 1.47 33958 18888 3 1664.816559 555.9459 "Cytochrome b-c1 complex subunit 2, mitochondrial OS=Homo sapiens OX=9606 GN=UQCRC2 PE=1 SV=3" 5.32 3189 - 2.81E+06 - - - 0.4349 - 2.624 0.545 - 169.6 1 2 0 0.0007 14 0 0 0 5.60E+07 3.81E+07 - - - 7.1797 1 221125_WJC_METTL3_EV_vs_WT_F03.18889.18889.3 1.24E-09 15/52 R.YEDFSNLGTTHLLR[166.11].L "sp|P22695|QCR2_HUMAN,tr|H3BP04|H3BP04_HUMAN,tr|H3BUE4|H3BUE4_HUMAN,tr|H3BUI9|H3BUI9_HUMAN,tr|H3BRG4|H3BRG4_HUMAN,tr|H3BSJ9|H3BSJ9_HUMAN,tr|A0A087WVZ4|A0A087WVZ4_HUMAN" 7 1674.8241 1.47 33959 18889 3 1674.82389 559.282 "Cytochrome b-c1 complex subunit 2, mitochondrial OS=Homo sapiens OX=9606 GN=UQCRC2 PE=1 SV=3" 5.32 3189.1 - 2.36E+06 - - - -0.1284 - 2.98 0.583 - 189.5 1 2 0 -0.0002 14 0 0 0 5.60E+07 3.81E+07 - - - 7.9416 0.9988 221125_WJC_METTL3_EV_vs_WT_F03.18891.18891.3 0.00916 Sep-44 K.ELVTQQLPHLLK.D sp|Q99584|S10AD_HUMAN 1 1417.8293 1.74 33961 18891 3 1417.829224 473.617 Protein S100-A13 OS=Homo sapiens OX=9606 GN=S100A13 PE=1 SV=1 6.85 3189.3 - 1.21E+06 - - - -0.0536 - 1.785 0.272 - 112.6 1 2 0 -0.0001 12 0 0 0 2.05E+08 1.18E+08 - - - 3.1786 0.9983 221125_WJC_METTL3_EV_vs_WT_F03.18893.18893.3 0.0477 Nov-44 K.ELVTQQLPHLLK[136.11].D sp|Q99584|S10AD_HUMAN 1 1425.8435 1.76 33963 18893 3 1425.843991 476.2884 Protein S100-A13 OS=Homo sapiens OX=9606 GN=S100A13 PE=1 SV=1 6.85 3189.5 - 814089 - - - 0.3444 - 1.787 0.25 - 183.6 1 2 0 0.0005 12 0 0 0 2.04E+08 1.16E+08 - - - 2.9363 0.9999 221125_WJC_METTL3_EV_vs_WT_F03.18894.18894.3 0.00256 14/52 R.SLGEIPIVESEIK[136.11]K[136.11].E sp|P53618|COPB_HUMAN 1 1556.8996 1.05 33964 18894 3 1556.900558 519.9738 Coatomer subunit beta OS=Homo sapiens OX=9606 GN=COPB1 PE=1 SV=3 4.78 3189.6 - 718802 - - - 0.5993 - 1.959 0.429 - 171.1 1 2 0 0.0009 14 0 0 0 8.67E+06 8.29E+06 - - - 5.1097 0.9996 221125_WJC_METTL3_EV_vs_WT_F03.18895.18895.2 7.33E-05 18-Nov K.FAAQELIEVK[136.11].R "sp|Q86U44|MTA70_HUMAN,tr|F5H6D8|F5H6D8_HUMAN,tr|H0YFV6|H0YFV6_HUMAN,tr|B4DTN4|B4DTN4_HUMAN" 4 1154.6427 0.12 33965 18895 2 1154.644762 578.3286 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 4.53 3189.7 - 651268 - - - 1.8075 - 2.035 0.426 - 287.5 1 2 0 0.0021 10 0 0 0 7.62E+05 6.36E+06 - - - 4.17 1 221125_WJC_METTL3_EV_vs_WT_F03.18897.18897.2 3.30E-07 22-Dec R.ENEFSFEDNAIR[166.11].G "sp|Q14839|CHD4_HUMAN,sp|Q8TDI0|CHD5_HUMAN,tr|A0A2R8Y4X2|A0A2R8Y4X2_HUMAN,tr|A0A2U3TZM0|A0A2U3TZM0_HUMAN,tr|A0A2R8Y685|A0A2R8Y685_HUMAN,tr|A0A2R8Y445|A0A2R8Y445_HUMAN,tr|F2Z2R5|F2Z2R5_HUMAN,tr|A0A2R8YD40|A0A2R8YD40_HUMAN,tr|A0A2R8Y5J0|A0A2R8Y5J0_HUMAN,tr|A0A2R8Y425|A0A2R8Y425_HUMAN,tr|A0A2R8YFK9|A0A2R8YFK9_HUMAN,tr|A0A2R8Y8B3|A0A2R8Y8B3_HUMAN,tr|A0A2R8Y8C1|A0A2R8Y8C1_HUMAN,tr|A0A0C4DGG9|A0A0C4DGG9_HUMAN,tr|A0A2R8YFD8|A0A2R8YFD8_HUMAN,tr|A0A2R8YDW2|A0A2R8YDW2_HUMAN,tr|A0A2R8Y5Z7|A0A2R8Y5Z7_HUMAN,tr|F5GWX5|F5GWX5_HUMAN,tr|K7EMY3|K7EMY3_HUMAN,tr|A0A2R8YER1|A0A2R8YER1_HUMAN,tr|A0A2R8Y521|A0A2R8Y521_HUMAN,tr|A0A2R8YDJ9|A0A2R8YDJ9_HUMAN,tr|A0A2R8Y212|A0A2R8Y212_HUMAN" 23 1479.6506 0.68 33967 18897 2 1479.654656 740.8326 Chromodomain-helicase-DNA-binding protein 4 OS=Homo sapiens OX=9606 GN=CHD4 PE=1 SV=2 4 3190 - 519704 - - - 2.7702 - 2.428 0.595 - 666.7 1 2 0 0.0041 12 0 0 0 9.81E+06 1.45E+07 - - - 5.7684 0.9999 221125_WJC_METTL3_EV_vs_WT_F03.18898.18898.2 3.58E-06 14/24 R.AQSPGAVEEILDR[166.11].E "sp|Q9NYM9|BET1L_HUMAN,tr|A0A0C4DH16|A0A0C4DH16_HUMAN,tr|B8ZZS0|B8ZZS0_HUMAN,tr|E9PHY4|E9PHY4_HUMAN,tr|H7BXT7|H7BXT7_HUMAN" 5 1393.7077 3.2 33968 18898 2 1393.706907 697.8611 BET1-like protein OS=Homo sapiens OX=9606 GN=BET1L PE=1 SV=1 4.14 3190.1 - 443771 - - - -0.5532 - 2.635 0.52 - 846.5 1 2 0 -0.0008 13 0 0 0 1.48E+07 4.64E+06 - - - 5.3681 0.9532 221125_WJC_METTL3_EV_vs_WT_F03.18899.18899.2 2.21E-07 30-Nov K.AGTDPNSAAWAAYYAH.Y "sp|Q96AE4|FUBP1_HUMAN,tr|E9PEB5|E9PEB5_HUMAN" 2 1664.7219 - 33969 18899 2 1664.728483 833.3682 Far upstream element-binding protein 1 OS=Homo sapiens OX=9606 GN=FUBP1 PE=1 SV=3 5.08 3190.3 - 376155 - - - 3.9334 - 2.165 0.614 - 305.1 1 1 0 0.0065 16 0 0 0 - - - - - 5.473 0.9983 221125_WJC_METTL3_EV_vs_WT_F03.18901.18901.3 1.37E-06 15/40 L.PVDLAEELGHR.D "sp|P42771|CDN2A_HUMAN,tr|K7ENC6|K7ENC6_HUMAN,tr|J3QRG6|J3QRG6_HUMAN,tr|K7ES20|K7ES20_HUMAN" 4 1234.6306 1.95 33971 18901 3 1234.631438 412.5508 Cyclin-dependent kinase inhibitor 2A OS=Homo sapiens OX=9606 GN=CDKN2A PE=1 SV=2 4.65 3190.5 - 354101 - - - 0.6787 - 2.859 0.529 - 333.9 1 1 0 0.0008 11 0 0 0 4.37E+06 2.24E+06 - - - 7.4218 0.9995 221125_WJC_METTL3_EV_vs_WT_F03.18905.18905.3 0.00497 13/40 K.FEPFVLHVQC[160.03]R[166.11].Q sp|Q6IPR3|TYW3_HUMAN 1 1440.7212 1.35 33975 18905 3 1440.718197 481.2477 tRNA wybutosine-synthesizing protein 3 homolog OS=Homo sapiens OX=9606 GN=TYW3 PE=1 SV=2 6.74 3191 - 237197 - - - -2.0566 - 2.001 0.341 - 172 1 2 0 -0.003 11 0 0 0 2.26E+06 1.68E+06 - - - 4.3115 0.9999 221125_WJC_METTL3_EV_vs_WT_F03.18908.18908.3 0.000113 Oct-52 K.IAILTC[160.03]PFEPPK[136.11]PK[136.11].T "sp|P48643|TCPE_HUMAN,tr|E9PCA1|E9PCA1_HUMAN,tr|B7ZAR1|B7ZAR1_HUMAN,tr|E7ENZ3|E7ENZ3_HUMAN" 4 1625.9186 0.68 33976 18908 3 1625.920103 542.9801 T-complex protein 1 subunit epsilon OS=Homo sapiens OX=9606 GN=CCT5 PE=1 SV=1 8.2 3191.5 - 1.23E+07 - - - 0.933 - 2.325 0.46 - 119.5 1 2 0 0.0015 14 0 0 0 1.06E+09 1.56E+09 - - - 5.9103 0.9997 221125_WJC_METTL3_EV_vs_WT_F03.18909.18909.2 2.04E-05 16-Dec R.TGHWLNHGK[136.11].E sp|Q86U44|MTA70_HUMAN 1 1056.5345 0.31 33977 18909 2 1056.535512 529.2745 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 8.47 3191.5 - 4.79E+06 - - - 0.9938 - 2.111 0.354 - 452.8 1 2 0 0.001 9 0 0 0 1.46E+07 4.74E+07 - - - 3.8169 0.9999 221125_WJC_METTL3_EV_vs_WT_F03.18911.18911.2 2.05E-07 14/22 R.LPVDLAEELGHR.D "sp|P42771|CDN2A_HUMAN,tr|K7ENC6|K7ENC6_HUMAN,tr|J3QRG6|J3QRG6_HUMAN,tr|K7ES20|K7ES20_HUMAN" 4 1347.7147 1.81 33979 18911 2 1347.713667 674.8646 Cyclin-dependent kinase inhibitor 2A OS=Homo sapiens OX=9606 GN=CDKN2A PE=1 SV=2 4.65 3191.6 - 2.66E+06 - - - -0.7398 - 2.599 0.558 - 754.3 1 2 0 -0.001 12 0 0 0 1.76E+07 9.72E+06 - - - 5.6752 1 221125_WJC_METTL3_EV_vs_WT_F03.18915.18915.3 8.57E-14 22/68 R.K[136.11]VPGVTAIELDEDTGTFR[166.11].L "sp|P51114|FXR1_HUMAN,tr|E7EU85|E7EU85_HUMAN,tr|E9PFF5|E9PFF5_HUMAN,tr|B4DXZ6|B4DXZ6_HUMAN" 4 1965.0174 1.44 33983 18915 3 1965.018735 656.0131 Fragile X mental retardation syndrome-related protein 1 OS=Homo sapiens OX=9606 GN=FXR1 PE=1 SV=3 4.32 3191.9 - 1.33E+06 - - - 0.6835 - 3.751 0.652 - 741.8 1 2 0 0.0013 18 0 0 0 5.50E+07 3.81E+07 - - - 9.1008 1 221125_WJC_METTL3_EV_vs_WT_F03.18916.18916.2 1.10E-06 14/22 R.LPVDLAEELGHR[166.11].D "sp|P42771|CDN2A_HUMAN,tr|K7ENC6|K7ENC6_HUMAN,tr|J3QRG6|J3QRG6_HUMAN,tr|K7ES20|K7ES20_HUMAN" 4 1357.7229 1.81 33984 18916 2 1357.723854 679.8687 Cyclin-dependent kinase inhibitor 2A OS=Homo sapiens OX=9606 GN=CDKN2A PE=1 SV=2 4.65 3192 - 1.20E+06 - - - 0.6776 - 2.612 0.61 - 1097.4 1 2 0 0.0009 12 0 0 0 1.76E+07 9.72E+06 - - - 6.0724 0.9998 221125_WJC_METTL3_EV_vs_WT_F03.18918.18918.2 5.14E-05 22-Nov R.ENEFSFEDNAIR.G "sp|Q14839|CHD4_HUMAN,sp|Q8TDI0|CHD5_HUMAN,tr|A0A2R8Y4X2|A0A2R8Y4X2_HUMAN,tr|A0A2U3TZM0|A0A2U3TZM0_HUMAN,tr|A0A2R8Y685|A0A2R8Y685_HUMAN,tr|A0A2R8Y445|A0A2R8Y445_HUMAN,tr|F2Z2R5|F2Z2R5_HUMAN,tr|A0A2R8YD40|A0A2R8YD40_HUMAN,tr|A0A2R8Y5J0|A0A2R8Y5J0_HUMAN,tr|A0A2R8Y425|A0A2R8Y425_HUMAN,tr|A0A2R8YFK9|A0A2R8YFK9_HUMAN,tr|A0A2R8Y8B3|A0A2R8Y8B3_HUMAN,tr|A0A2R8Y8C1|A0A2R8Y8C1_HUMAN,tr|A0A0C4DGG9|A0A0C4DGG9_HUMAN,tr|A0A2R8YFD8|A0A2R8YFD8_HUMAN,tr|A0A2R8YDW2|A0A2R8YDW2_HUMAN,tr|A0A2R8Y5Z7|A0A2R8Y5Z7_HUMAN,tr|F5GWX5|F5GWX5_HUMAN,tr|K7EMY3|K7EMY3_HUMAN,tr|A0A2R8YER1|A0A2R8YER1_HUMAN,tr|A0A2R8Y521|A0A2R8Y521_HUMAN,tr|A0A2R8YDJ9|A0A2R8YDJ9_HUMAN,tr|A0A2R8Y212|A0A2R8Y212_HUMAN" 23 1469.6423 0.68 33986 18918 2 1469.644359 735.8284 Chromodomain-helicase-DNA-binding protein 4 OS=Homo sapiens OX=9606 GN=CHD4 PE=1 SV=2 4 3192.2 - 714866 - - - 1.4099 - 2.401 0.524 - 428.4 1 2 0 0.0021 12 0 0 0 9.81E+06 1.45E+07 - - - 5.2152 0.9998 221125_WJC_METTL3_EV_vs_WT_F03.18919.18919.2 1.65E-05 15/26 K.VLEQLTGQTPVFSK.A "sp|P62913|RL11_HUMAN,tr|Q5VVC8|Q5VVC8_HUMAN" 2 1545.8403 1.19 33987 18919 2 1545.837829 773.9274 60S ribosomal protein L11 OS=Homo sapiens OX=9606 GN=RPL11 PE=1 SV=2 5.97 3192.4 - 644038 - - - -1.572 - 2.829 0.496 - 811.8 1 2 0 -0.0024 14 0 0 0 1.56E+09 1.31E+09 - - - 5.3133 0.9998 221125_WJC_METTL3_EV_vs_WT_F03.18920.18920.2 1.57E-05 20-Nov K.NYPDPVSIIQK[136.11].Y "sp|P41252|SYIC_HUMAN,tr|A0A804HL54|A0A804HL54_HUMAN,tr|A0A804HKU1|A0A804HKU1_HUMAN,tr|A0A804HK69|A0A804HK69_HUMAN,tr|A0A804HIV9|A0A804HIV9_HUMAN,tr|A0A804HJN6|A0A804HJN6_HUMAN,tr|A0A804HHW9|A0A804HHW9_HUMAN,tr|A0A0A0MSX9|A0A0A0MSX9_HUMAN,tr|J3KR24|J3KR24_HUMAN,tr|A0A804HJ36|A0A804HJ36_HUMAN" 10 1280.6856 1.03 33988 18920 2 1280.685929 641.3501 "Isoleucine--tRNA ligase, cytoplasmic OS=Homo sapiens OX=9606 GN=IARS1 PE=1 SV=2" 5.83 3192.5 - 598857 - - - 0.2546 - 1.945 0.446 - 306.8 1 2 0 0.0003 11 0 0 0 8.66E+06 8.38E+06 - - - 4.1347 1 221125_WJC_METTL3_EV_vs_WT_F03.18923.18923.3 3.00E-05 18/56 K.GLPDAHLGLPPGLAK.K "sp|O95785|WIZ_HUMAN,tr|A0A669KBG4|A0A669KBG4_HUMAN,tr|A0A2R8YFV2|A0A2R8YFV2_HUMAN,tr|A0A669KAV7|A0A669KAV7_HUMAN,tr|M0QXA7|M0QXA7_HUMAN,tr|A0A669KBH9|A0A669KBH9_HUMAN,tr|B9EGQ5|B9EGQ5_HUMAN" 7 1454.8245 1.41 33991 18923 3 1454.826235 485.9488 Protein Wiz OS=Homo sapiens OX=9606 GN=WIZ PE=1 SV=2 6.74 3192.9 - 477910 - - - 1.1589 - 3.059 0.51 - 335.9 1 2 0 0.0017 15 0 0 0 8.26E+06 5.87E+06 - - - 7.143 0.9998 221125_WJC_METTL3_EV_vs_WT_F03.18924.18924.2 0.000139 26-Nov R.VVQMLGSLGGQINK.N sp|P78527|PRKDC_HUMAN 1 1442.7915 0.93 33992 18924 2 1442.793587 722.403 DNA-dependent protein kinase catalytic subunit OS=Homo sapiens OX=9606 GN=PRKDC PE=1 SV=3 8.72 3193 - 474287 - - - 1.4222 - 2.657 0.511 - 351 1 2 0 0.0021 14 0 0 0 6.34E+06 6.81E+06 - - - 5.2668 1 221125_WJC_METTL3_EV_vs_WT_F03.18925.18925.3 2.44E-05 13/44 K.KVVVEQLNLLVK.R "sp|P34949|MPI_HUMAN,tr|H3BPB8|H3BPB8_HUMAN,tr|H3BP57|H3BP57_HUMAN,tr|H3BT48|H3BT48_HUMAN,tr|H3BUZ9|H3BUZ9_HUMAN,tr|H3BPP3|H3BPP3_HUMAN,tr|F5GX71|F5GX71_HUMAN,tr|H3BMZ9|H3BMZ9_HUMAN" 8 1380.8704 1.41 33993 18925 3 1380.871239 461.2974 Mannose-6-phosphate isomerase OS=Homo sapiens OX=9606 GN=MPI PE=1 SV=2 8.59 3193.1 - 468558 - - - 0.5808 - 2.382 0.473 - 196.1 1 2 0 0.0008 12 0 0 0 1.61E+07 1.15E+07 - - - 6.2191 0.9999 221125_WJC_METTL3_EV_vs_WT_F03.18926.18926.3 2.29E-05 Dec-48 R.SLLQTTFLVDNKK.V sp|Q5VZE5|NAA35_HUMAN 1 1505.8453 0.39 33994 18926 3 1505.844165 502.9557 "N-alpha-acetyltransferase 35, NatC auxiliary subunit OS=Homo sapiens OX=9606 GN=NAA35 PE=1 SV=1" 8.31 3193.3 - 384714 - - - -0.7829 - 2.302 0.412 - 132.4 1 2 0 -0.0012 13 0 0 0 3.47E+06 8.83E+06 - - - 5.3937 0.9999 221125_WJC_METTL3_EV_vs_WT_F03.18930.18930.2 1.93E-08 26-Nov R.EWNLPPNAPAC[160.03]MER.Q sp|Q9BQA1|MEP50_HUMAN 1 1683.7497 5.5 33997 18930 2 1683.751667 842.8821 Methylosome protein 50 OS=Homo sapiens OX=9606 GN=WDR77 PE=1 SV=1 4.53 3193.8 - 710355 - - - 1.1409 - 2.475 0.558 - 288.7 1 2 0 0.0019 14 0 0 0 5.32E+06 9.66E+05 - - - 5.4359 0.9996 221125_WJC_METTL3_EV_vs_WT_F03.18933.18933.3 5.13E-06 15/52 R.VIK[136.11]DFMIQGGDFTR[166.11].G "sp|P23284|PPIB_HUMAN,tr|A0A7P0Z497|A0A7P0Z497_HUMAN,tr|A0A7P0T7U3|A0A7P0T7U3_HUMAN,tr|A0A7P0TB45|A0A7P0TB45_HUMAN" 4 1643.846 0.27 34000 18933 3 1643.851241 548.956 Peptidyl-prolyl cis-trans isomerase B OS=Homo sapiens OX=9606 GN=PPIB PE=1 SV=2 5.93 3193.9 - 3.76E+06 - - - 3.1682 - 2.843 0.521 - 310.6 1 2 1 0.0052 14 0 0 0 1.52E+07 5.65E+07 - - - 7.1239 0.9999 221125_WJC_METTL3_EV_vs_WT_F03.18935.18935.3 0.0012 13/52 K.VLEQLTGQTPVFSK[136.11].A "sp|P62913|RL11_HUMAN,tr|Q5VVC8|Q5VVC8_HUMAN" 2 1553.8545 1.22 34002 18935 3 1553.855573 518.9588 60S ribosomal protein L11 OS=Homo sapiens OX=9606 GN=RPL11 PE=1 SV=2 5.97 3194 - 1.61E+06 - - - 0.7169 - 2.475 0.427 - 252.3 1 2 0 0.0011 14 0 0 0 6.95E+08 5.71E+08 - - - 5.7087 1 221125_WJC_METTL3_EV_vs_WT_F03.18936.18936.3 9.25E-06 14/44 K.K[136.11]VVVEQLNLLVK[136.11].R "sp|P34949|MPI_HUMAN,tr|H3BPB8|H3BPB8_HUMAN,tr|H3BP57|H3BP57_HUMAN,tr|H3BT48|H3BT48_HUMAN,tr|H3BUZ9|H3BUZ9_HUMAN,tr|H3BPP3|H3BPP3_HUMAN,tr|F5GX71|F5GX71_HUMAN,tr|H3BMZ9|H3BMZ9_HUMAN" 8 1396.8988 1.41 34003 18936 3 1396.898397 466.6402 Mannose-6-phosphate isomerase OS=Homo sapiens OX=9606 GN=MPI PE=1 SV=2 8.59 3194.1 - 1.33E+06 - - - -0.315 - 2.988 0.538 - 471.6 1 2 0 -0.0004 12 0 0 0 1.61E+07 1.15E+07 - - - 7.5721 1 221125_WJC_METTL3_EV_vs_WT_F03.18940.18940.3 0.000863 18/56 K.GLPDAHLGLPPGLAK[136.11].K "sp|O95785|WIZ_HUMAN,tr|A0A669KBG4|A0A669KBG4_HUMAN,tr|A0A2R8YFV2|A0A2R8YFV2_HUMAN,tr|A0A669KAV7|A0A669KAV7_HUMAN,tr|M0QXA7|M0QXA7_HUMAN,tr|A0A669KBH9|A0A669KBH9_HUMAN,tr|B9EGQ5|B9EGQ5_HUMAN" 7 1462.8387 1.41 34007 18940 3 1462.839336 488.6202 Protein Wiz OS=Homo sapiens OX=9606 GN=WIZ PE=1 SV=2 6.74 3194.5 - 827394 - - - 0.4013 - 2.731 0.467 - 311.7 1 2 0 0.0006 15 0 0 0 8.26E+06 5.87E+06 - - - 6.368 0.9977 221125_WJC_METTL3_EV_vs_WT_F03.18945.18945.3 0.00758 Sep-40 R.LIHQLLTDIGR[166.11].Y "sp|P42345|MTOR_HUMAN,tr|B1AKP8|B1AKP8_HUMAN" 2 1287.7538 1.01 34012 18945 3 1287.754062 430.2586 Serine\threonine-protein kinase mTOR OS=Homo sapiens OX=9606 GN=MTOR PE=1 SV=1 6.74 3195.1 - 380828 - - - 0.1716 - 1.698 0.242 - 153.6 1 2 0 0.0002 11 0 0 0 1.29E+06 1.27E+06 - - - 2.7421 0.9997 221125_WJC_METTL3_EV_vs_WT_F03.18946.18946.2 0.00536 22-Oct K.ELALPGELTQSR[166.11].S "sp|O75436|VP26A_HUMAN,tr|S4R3Q6|S4R3Q6_HUMAN" 2 1322.707 2.04 34013 18946 2 1322.707434 662.3608 Vacuolar protein sorting-associated protein 26A OS=Homo sapiens OX=9606 GN=VPS26A PE=1 SV=2 4.53 3195.3 - 372639 - - - 0.3659 - 2.109 0.347 - 224.3 1 2 0 0.0005 12 0 0 0 8.32E+06 4.07E+06 - - - 3.5672 0.9771 221125_WJC_METTL3_EV_vs_WT_F03.18947.18947.3 0.391 Oct-40 R.LALSLFRPGGR.A sp|Q9H7N4|SFR19_HUMAN 1 1185.6982 2.01 34014 18947 3 1185.697012 396.24 "Splicing factor, arginine\serine-rich 19 OS=Homo sapiens OX=9606 GN=SCAF1 PE=1 SV=3" 12 3195.4 - 360334 - - - -1.0239 - 1.675 0.118 - 116.5 1 2 0 -0.0012 11 0 0 0 8.64E+06 4.31E+06 - - - 1.3206 1 221125_WJC_METTL3_EV_vs_WT_F03.18950.18950.3 3.60E-08 16/40 K.TSFHALTSILK[136.11].A "sp|Q02978|M2OM_HUMAN,tr|I3L1P8|I3L1P8_HUMAN" 2 1224.6958 0.9 34016 18950 3 1224.696176 409.2392 Mitochondrial 2-oxoglutarate\malate carrier protein OS=Homo sapiens OX=9606 GN=SLC25A11 PE=1 SV=3 8.44 3195.9 - 854289 - - - 0.3291 - 2.67 0.49 - 309 1 2 0 0.0004 11 0 0 0 4.31E+06 4.76E+06 - - - 6.7928 1 221125_WJC_METTL3_EV_vs_WT_F03.18952.18952.2 1.11E-07 14/26 K.VLEQLTGQTPVFSK[136.11].A "sp|P62913|RL11_HUMAN,tr|Q5VVC8|Q5VVC8_HUMAN" 2 1553.8545 1.19 34017 18952 2 1553.853717 777.9345 60S ribosomal protein L11 OS=Homo sapiens OX=9606 GN=RPL11 PE=1 SV=2 5.97 3196.1 - 1.43E+07 - - - -0.4775 - 2.886 0.585 - 762.9 1 2 0 -0.0007 14 0 0 0 1.56E+09 1.31E+09 - - - 6.0213 1 221125_WJC_METTL3_EV_vs_WT_F03.18954.18954.3 6.35E-09 13/52 R.IVDDWANDGWGLK[136.11]K[136.11].A "sp|P27824|CALX_HUMAN,tr|A0A7P0T937|A0A7P0T937_HUMAN,tr|A0A7P0T840|A0A7P0T840_HUMAN,tr|A0A7P0TB65|A0A7P0TB65_HUMAN,tr|A0A7P0TAE9|A0A7P0TAE9_HUMAN,tr|D6RGY2|D6RGY2_HUMAN,tr|A0A7P0T8G1|A0A7P0T8G1_HUMAN,tr|A0A7P0Z4D6|A0A7P0Z4D6_HUMAN,tr|A0A7P0T9L0|A0A7P0T9L0_HUMAN" 9 1631.8279 1 34019 18954 3 1631.826334 544.9499 Calnexin OS=Homo sapiens OX=9606 GN=CANX PE=1 SV=2 4.43 3196.2 - 1.12E+07 - - - -0.9333 - 2.353 0.602 - 160.2 1 2 0 -0.0015 14 0 0 0 7.23E+07 7.22E+07 - - - 7.5253 0.9988 221125_WJC_METTL3_EV_vs_WT_F03.18958.18958.3 0.0596 Nov-44 R.SIVQIIYDENRK.K "sp|O75376|NCOR1_HUMAN,sp|Q9Y618|NCOR2_HUMAN,tr|C9JQE8|C9JQE8_HUMAN,tr|C9JE98|C9JE98_HUMAN,tr|H0YGK8|H0YGK8_HUMAN,tr|C9J330|C9J330_HUMAN,tr|E7EVU5|E7EVU5_HUMAN,tr|J3KS51|J3KS51_HUMAN,tr|C9J0Q5|C9J0Q5_HUMAN,tr|E7EW50|E7EW50_HUMAN,tr|A0A088AWL3|A0A088AWL3_HUMAN" 11 1476.7936 1.71 34023 18958 3 1476.792032 493.2718 Nuclear receptor corepressor 1 OS=Homo sapiens OX=9606 GN=NCOR1 PE=1 SV=2 5.79 3196.5 - 1.46E+06 - - - -1.0909 - 2.192 0.225 - 136.7 1 2 0 -0.0016 12 0 0 0 9.33E+06 5.46E+06 - - - 3.2235 0.8839 221125_WJC_METTL3_EV_vs_WT_F03.18959.18959.2 0.00274 16-Jun R.YC[160.03]VQLSQIQ.G "sp|Q04695|K1C17_HUMAN,sp|P13645|K1C10_HUMAN,tr|A0A1B0GVI3|A0A1B0GVI3_HUMAN,tr|F5GWP8|F5GWP8_HUMAN" 4 1137.5488 - 34024 18959 2 1137.544966 569.7817 "Keratin, type I cytoskeletal 17 OS=Homo sapiens OX=9606 GN=KRT17 PE=1 SV=2" 5.52 3196.6 - 1.42E+06 - - - -3.41 - 1.41 0.451 - 122.8 1 1 0 -0.0039 9 0 0 0 - - - - - 3.3649 1 221125_WJC_METTL3_EV_vs_WT_F03.18966.18966.2 2.21E-13 16/34 R.IGSSLYALGTQDSTDIC[160.03]K.F "sp|Q9UNH7|SNX6_HUMAN,tr|A0A0A0MRI2|A0A0A0MRI2_HUMAN" 2 1927.9197 2.03 34031 18966 2 1927.917906 964.9671 Sorting nexin-6 OS=Homo sapiens OX=9606 GN=SNX6 PE=1 SV=1 4.21 3197.5 - 565221 - - - -0.9347 - 3.338 0.715 - 751.9 1 2 0 -0.0018 18 0 0 0 3.54E+06 1.75E+06 - - - 7.2849 0.9981 221125_WJC_METTL3_EV_vs_WT_F03.18968.18968.3 0.000586 Aug-40 K.MTPPIK[136.11]DLLPR[166.11].L "sp|O75533|SF3B1_HUMAN,tr|H7C341|H7C341_HUMAN" 2 1297.7547 2.29 34033 18968 3 1297.753319 433.5922 Splicing factor 3B subunit 1 OS=Homo sapiens OX=9606 GN=SF3B1 PE=1 SV=3 8.5 3197.7 - 473901 - - - -1.0634 - 1.716 0.352 - 64.4 1 2 1 -0.0014 11 0 0 0 7.03E+06 3.07E+06 - - - 3.9981 1 221125_WJC_METTL3_EV_vs_WT_F03.18969.18969.2 9.47E-08 13/30 K.TTGTPPDSSLVTYELH.S "sp|Q13561|DCTN2_HUMAN,tr|H0YI98|H0YI98_HUMAN,tr|A8K8J9|A8K8J9_HUMAN,tr|A0A7I2V5R4|A0A7I2V5R4_HUMAN,tr|F8W1I6|F8W1I6_HUMAN,tr|A0A7I2V4H4|A0A7I2V4H4_HUMAN,tr|A0A7I2V390|A0A7I2V390_HUMAN,tr|A0A7I2V4Y9|A0A7I2V4Y9_HUMAN,tr|F8VW18|F8VW18_HUMAN" 9 1716.8206 - 34034 18969 2 1716.821764 859.4176 Dynactin subunit 2 OS=Homo sapiens OX=9606 GN=DCTN2 PE=1 SV=4 4.35 3197.9 - 424609 - - - 0.6512 - 2.476 0.61 - 410.4 1 1 0 0.0011 16 0 0 0 - - - - - 5.7751 0.9998 221125_WJC_METTL3_EV_vs_WT_F03.18974.18974.3 0.000224 Oct-52 R.IVDDWANDGWGLKK.A "sp|P27824|CALX_HUMAN,tr|A0A7P0T937|A0A7P0T937_HUMAN,tr|A0A7P0T840|A0A7P0T840_HUMAN,tr|A0A7P0TB65|A0A7P0TB65_HUMAN,tr|A0A7P0TAE9|A0A7P0TAE9_HUMAN,tr|D6RGY2|D6RGY2_HUMAN,tr|A0A7P0T8G1|A0A7P0T8G1_HUMAN,tr|A0A7P0Z4D6|A0A7P0Z4D6_HUMAN,tr|A0A7P0T9L0|A0A7P0T9L0_HUMAN" 9 1615.7995 1.01 34038 18974 3 1615.801216 539.6071 Calnexin OS=Homo sapiens OX=9606 GN=CANX PE=1 SV=2 4.43 3198.4 - 1.29E+07 - - - 1.0886 - 1.846 0.423 - 84.3 1 2 0 0.0018 14 0 0 0 7.19E+07 7.11E+07 - - - 4.8847 1 221125_WJC_METTL3_EV_vs_WT_F03.18975.18975.3 3.32E-08 16/68 R.KVPGVTAIELDEDTGTFR.L "sp|P51114|FXR1_HUMAN,tr|E7EU85|E7EU85_HUMAN,tr|E9PFF5|E9PFF5_HUMAN,tr|B4DXZ6|B4DXZ6_HUMAN" 4 1946.9949 1.44 34039 18975 3 1946.995135 650.0056 Fragile X mental retardation syndrome-related protein 1 OS=Homo sapiens OX=9606 GN=FXR1 PE=1 SV=3 4.32 3198.4 - 7.80E+06 - - - 0.1094 - 3.235 0.603 - 346.6 1 2 0 0.0002 18 0 0 0 5.50E+07 3.81E+07 - - - 8.1862 1 221125_WJC_METTL3_EV_vs_WT_F03.18976.18976.3 7.04E-06 14/60 K.TVVSHSLTTLGLEVAK[136.11].Q sp|P42166|LAP2A_HUMAN 1 1661.9443 0.62 34040 18976 3 1661.94438 554.9887 "Lamina-associated polypeptide 2, isoform alpha OS=Homo sapiens OX=9606 GN=TMPO PE=1 SV=2" 6.41 3198.5 - 3.63E+06 - - - 0.0259 - 2.928 0.449 - 145.1 1 2 0 0 16 0 0 0 1.44E+07 2.34E+07 - - - 6.3025 1 221125_WJC_METTL3_EV_vs_WT_F03.18977.18977.3 5.26E-05 14/56 R.LGPNYLHIPVNC[160.03]PYR.A sp|P04040|CATA_HUMAN 1 1811.9141 5.38 34041 18977 3 1811.912025 604.9786 Catalase OS=Homo sapiens OX=9606 GN=CAT PE=1 SV=3 8.21 3198.5 - 3.48E+06 - - - -1.1507 - 2.642 0.457 - 194.6 1 2 0 -0.0021 15 0 0 0 2.78E+07 5.17E+06 - - - 6.1696 0.9998 221125_WJC_METTL3_EV_vs_WT_F03.18979.18979.2 0.000104 13/24 R.ELLSISSESLQAR.K sp|Q9BRV8|SIKE1_HUMAN 1 1431.7569 999 34043 18979 2 1431.75872 716.8857 Suppressor of IKBKE 1 OS=Homo sapiens OX=9606 GN=SIKE1 PE=1 SV=1 4.53 3198.7 - 1.59E+06 - - - 1.2551 - 2.46 0.464 - 551.9 1 2 0 0.0018 13 0 0 0 9.31E+06 0.00E+00 - - - 4.7778 0.9999 221125_WJC_METTL3_EV_vs_WT_F03.18980.18980.2 4.61E-06 14/24 R.STVAESVSQQILR.Q sp|Q86WX3|AROS_HUMAN 1 1416.7573 1.25 34044 18980 2 1416.756432 709.3859 Active regulator of SIRT1 OS=Homo sapiens OX=9606 GN=RPS19BP1 PE=1 SV=1 5.72 3198.8 - 1.56E+06 - - - -0.583 - 2.917 0.53 - 934 1 2 0 -0.0008 13 0 0 0 3.02E+07 2.41E+07 - - - 5.7029 1 221125_WJC_METTL3_EV_vs_WT_F03.18983.18983.3 2.61E-08 14/40 R.R[166.11]ILVATNLFGR[166.11].G "sp|Q13838|DX39B_HUMAN,sp|O00148|DX39A_HUMAN,tr|H0Y400|H0Y400_HUMAN,tr|Q5STU3|Q5STU3_HUMAN,tr|A0A0G2JJZ9|A0A0G2JJZ9_HUMAN,tr|A0A140T9X3|A0A140T9X3_HUMAN" 6 1278.7675 1.01 34047 18983 3 1278.768456 427.2631 Spliceosome RNA helicase DDX39B OS=Homo sapiens OX=9606 GN=DDX39B PE=1 SV=1 12 3199.1 - 929997 - - - 0.7241 - 2.725 0.516 - 440 1 2 0 0.0009 11 0 0 0 1.17E+07 1.16E+07 - - - 7.1405 0.9999 221125_WJC_METTL3_EV_vs_WT_F03.18987.18987.3 0.00566 Dec-64 K.LQPSSSPENSLDPFPPR.L "sp|Q8WWM7|ATX2L_HUMAN,tr|H3BUF6|H3BUF6_HUMAN" 2 1866.9112 2.56 34051 18987 3 1866.913446 623.311 Ataxin-2-like protein OS=Homo sapiens OX=9606 GN=ATXN2L PE=1 SV=2 4.37 3199.6 - 698675 - - - 1.2073 - 2.524 0.379 - 128 1 2 0 0.0023 17 0 0 0 1.26E+07 4.91E+06 - - - 5.1038 0.9949 221125_WJC_METTL3_EV_vs_WT_F03.18993.18993.3 7.36E-06 14/52 F.NQGLDC[160.03]DVIVAEVR[166.11].S sp|Q86U44|MTA70_HUMAN 1 1596.7805 0.02 34055 18993 3 1596.777316 533.2675 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 4.03 3200.4 - 6.78E+06 - - - -2.0103 - 2.385 0.52 - 321.8 1 1 0 -0.0032 14 0 0 0 6.99E+06 3.01E+08 - - - 6.6465 1 221125_WJC_METTL3_EV_vs_WT_F03.18994.18994.3 2.05E-07 21/64 R.LVGSQEELASWGHEYVR[166.11].H "sp|Q13200|PSMD2_HUMAN,tr|H7C2Q3|H7C2Q3_HUMAN" 2 1968.9569 0.64 34056 18994 3 1968.955394 657.3262 26S proteasome non-ATPase regulatory subunit 2 OS=Homo sapiens OX=9606 GN=PSMD2 PE=1 SV=3 4.75 3200.4 - 5.53E+06 - - - -0.77 - 3.501 0.553 - 445.1 1 2 0 -0.0015 17 0 0 0 1.76E+07 2.76E+07 - - - 7.8706 0.9991 221125_WJC_METTL3_EV_vs_WT_F03.18995.18995.2 0.00106 18-Nov K.VSEEIEDIIK.K "sp|O75223|GGCT_HUMAN,tr|M0QZK8|M0QZK8_HUMAN" 2 1173.6129 10.09 34057 18995 2 1173.616356 587.8137 Gamma-glutamylcyclotransferase OS=Homo sapiens OX=9606 GN=GGCT PE=1 SV=1 4 3200.5 - 5.26E+06 - - - 2.9575 - 2.159 0.4 - 559.4 1 2 0 0.0035 10 0 0 0 3.55E+07 3.52E+06 - - - 4.1426 1 221125_WJC_METTL3_EV_vs_WT_F03.18996.18996.3 5.09E-08 24/64 R.LVGSQEELASWGHEYVR.H "sp|Q13200|PSMD2_HUMAN,tr|H7C2Q3|H7C2Q3_HUMAN" 2 1958.9486 0.64 34058 18996 3 1958.951822 653.9902 26S proteasome non-ATPase regulatory subunit 2 OS=Homo sapiens OX=9606 GN=PSMD2 PE=1 SV=3 4.75 3200.6 - 3.24E+06 - - - 1.6243 - 4.21 0.516 - 617.4 1 2 0 0.0032 17 0 0 0 1.76E+07 2.76E+07 - - - 7.9235 0.9999 221125_WJC_METTL3_EV_vs_WT_F03.18997.18997.2 0.0114 15/24 R.STVAESVSQQILR[166.11].Q sp|Q86WX3|AROS_HUMAN 1 1426.7655 1.24 34059 18997 2 1426.766332 714.39 Active regulator of SIRT1 OS=Homo sapiens OX=9606 GN=RPS19BP1 PE=1 SV=1 5.72 3200.6 - 2.58E+06 - - - 0.5642 - 2.866 0.503 - 1009.4 1 2 0 0.0008 13 0 0 0 2.99E+07 2.41E+07 - - - 5.4582 1 221125_WJC_METTL3_EV_vs_WT_F03.18998.18998.3 0.00132 18/68 K.GVVSLVAVHPSTVNPLGK.Q "sp|Q14186|TFDP1_HUMAN,tr|F5H452|F5H452_HUMAN,tr|Q5JSB6|Q5JSB6_HUMAN,tr|Q5JSB5|Q5JSB5_HUMAN" 4 1773.0149 2.68 34060 18998 3 1773.016497 592.0122 Transcription factor Dp-1 OS=Homo sapiens OX=9606 GN=TFDP1 PE=1 SV=1 8.76 3200.7 - 2.22E+06 - - - 0.9182 - 2.961 0.429 - 316.5 1 2 0 0.0016 18 0 0 0 3.76E+07 1.40E+07 - - - 6.0255 1 221125_WJC_METTL3_EV_vs_WT_F03.18999.18999.3 5.83E-08 20/68 K.VIR[166.11]PLDQPSSFDATPYIK[136.11].D sp|Q86VP6|CAND1_HUMAN 1 2064.1011 0.69 34061 18999 3 2064.099734 689.041 Cullin-associated NEDD8-dissociated protein 1 OS=Homo sapiens OX=9606 GN=CAND1 PE=1 SV=2 5.93 3200.8 - 1.86E+06 - - - -0.6434 - 3.536 0.6 - 462.4 1 2 0 -0.0013 18 0 0 0 1.10E+07 1.60E+07 - - - 8.374 0.9999 221125_WJC_METTL3_EV_vs_WT_F03.19000.19000.3 0.00392 Dec-60 K.TVVSHSLTTLGLEVAK.Q sp|P42166|LAP2A_HUMAN 1 1653.9301 0.62 34062 19000 3 1653.932732 552.3173 "Lamina-associated polypeptide 2, isoform alpha OS=Homo sapiens OX=9606 GN=TMPO PE=1 SV=2" 6.41 3200.8 - 1.77E+06 - - - 1.569 - 2.419 0.403 - 96.7 1 2 0 0.0026 16 0 0 0 1.44E+07 2.34E+07 - - - 5.2989 1 221125_WJC_METTL3_EV_vs_WT_F03.19001.19001.3 4.63E-10 21/68 K.VIRPLDQPSSFDATPYIK.D sp|Q86VP6|CAND1_HUMAN 1 2046.0786 0.69 34063 19001 3 2046.083017 683.0335 Cullin-associated NEDD8-dissociated protein 1 OS=Homo sapiens OX=9606 GN=CAND1 PE=1 SV=2 5.93 3201 - 1.66E+06 - - - 2.1627 - 3.702 0.582 - 569.6 1 2 0 0.0044 18 0 0 0 1.11E+07 1.60E+07 - - - 8.2867 0.9995 221125_WJC_METTL3_EV_vs_WT_F03.19002.19002.3 0.000163 15/44 R.AK[136.11]ELLGQGLLLR[166.11].S "sp|Q99613|EIF3C_HUMAN,sp|B5ME19|EIFCL_HUMAN" 2 1327.8306 0.99 34064 19002 3 1327.830504 443.6175 Eukaryotic translation initiation factor 3 subunit C OS=Homo sapiens OX=9606 GN=EIF3C PE=1 SV=1 8.79 3201.1 - 1.43E+06 - - - -0.1032 - 2.533 0.353 - 327.7 1 2 1 -0.0001 12 0 0 0 2.18E+07 2.19E+07 - - - 5.0517 0.9999 221125_WJC_METTL3_EV_vs_WT_F03.19003.19003.2 0.00056 13/20 K.TIAQMIEDEQR[166.11].T "sp|O75410|TACC1_HUMAN,sp|O95359|TACC2_HUMAN,tr|E7EVI4|E7EVI4_HUMAN,tr|Q4VXL8|Q4VXL8_HUMAN,tr|Q4VXL4|Q4VXL4_HUMAN,tr|E7EMZ9|E7EMZ9_HUMAN,tr|H0Y9C3|H0Y9C3_HUMAN,tr|E9PBC6|E9PBC6_HUMAN,tr|E7ET87|E7ET87_HUMAN,tr|D6RAA5|D6RAA5_HUMAN" 10 1342.6426 1.15 34065 19003 2 1342.64268 672.3286 Transforming acidic coiled-coil-containing protein 1 OS=Homo sapiens OX=9606 GN=TACC1 PE=1 SV=2 4.14 3201.2 - 1.41E+06 - - - 0.0335 - 2.556 0.438 - 525.6 1 2 0 0 11 0 0 0 1.18E+08 1.03E+08 - - - 4.8148 0.9998 221125_WJC_METTL3_EV_vs_WT_F03.19005.19005.3 0.00698 18/44 R.AKELLGQGLLLR.S "sp|Q99613|EIF3C_HUMAN,sp|B5ME19|EIFCL_HUMAN" 2 1309.8082 0.99 34067 19005 3 1309.806971 437.61 Eukaryotic translation initiation factor 3 subunit C OS=Homo sapiens OX=9606 GN=EIF3C PE=1 SV=1 8.79 3201.5 - 1.05E+06 - - - -0.9162 - 3.072 0.401 - 606.9 1 2 1 -0.0012 12 0 0 0 2.18E+07 2.19E+07 - - - 6.1214 0.9998 221125_WJC_METTL3_EV_vs_WT_F03.19006.19006.2 1.36E-06 22-Dec K.GPSVFPLAPC[160.03]SR.S "sp|P01859|IGHG2_HUMAN,sp|P01860|IGHG3_HUMAN,sp|P01861|IGHG4_HUMAN,tr|A0A4W9A917|A0A4W9A917_HUMAN,tr|A0A286YES1|A0A286YES1_HUMAN,tr|A0A286YFJ8|A0A286YFJ8_HUMAN,tr|A0A286YEY4|A0A286YEY4_HUMAN" 7 1286.6441 0.63 34068 19006 2 1286.641965 644.3293 Immunoglobulin heavy constant gamma 2 OS=Homo sapiens OX=9606 GN=IGHG2 PE=1 SV=2 8.25 3201.6 - 1.01E+06 - - - -1.692 - 2.381 0.519 - 398.7 1 2 0 -0.0022 12 0 0 0 2.82E+07 4.47E+07 - - - 5.1562 0.9764 221125_WJC_METTL3_EV_vs_WT_F03.19007.19007.2 0.000436 24-Oct R.EAEDTQVFGDLPR.P sp|Q96B36|AKTS1_HUMAN 1 1475.6892 8.98 34069 19007 2 1475.691914 738.8519 Proline-rich AKT1 substrate 1 OS=Homo sapiens OX=9606 GN=AKT1S1 PE=1 SV=1 3.92 3201.7 - 982618 - - - 1.8134 - 2.318 0.395 - 181.7 1 1 0 0.0027 13 0 0 0 7.07E+06 7.88E+05 - - - 4.1153 1 221125_WJC_METTL3_EV_vs_WT_F03.19008.19008.2 2.33E-09 19/28 L.NEPTAAAIAYGLDK[136.11]K[136.11].G "sp|P54652|HSP72_HUMAN,sp|P11142|HSP7C_HUMAN,tr|E9PKE3|E9PKE3_HUMAN,tr|E9PN89|E9PN89_HUMAN,tr|E9PI65|E9PI65_HUMAN" 5 1576.8432 0.1 34070 19008 2 1576.852052 789.4289 Heat shock-related 70 kDa protein 2 OS=Homo sapiens OX=9606 GN=HSPA2 PE=1 SV=1 6.07 3201.9 - 797390 - - - 5.6315 - 3.08 0.596 - 1525.2 1 1 0 0.0089 15 0 0 0 1.70E+07 1.71E+08 - - - 6.206 0.9996 221125_WJC_METTL3_EV_vs_WT_F03.19009.19009.2 0.0265 20-Jul R.RILVATNLFGR.G "sp|Q13838|DX39B_HUMAN,sp|O00148|DX39A_HUMAN,tr|H0Y400|H0Y400_HUMAN,tr|Q5STU3|Q5STU3_HUMAN,tr|A0A0G2JJZ9|A0A0G2JJZ9_HUMAN,tr|A0A140T9X3|A0A140T9X3_HUMAN" 6 1258.751 1.27 34071 19009 2 1258.750249 630.3828 Spliceosome RNA helicase DDX39B OS=Homo sapiens OX=9606 GN=DDX39B PE=1 SV=1 12 3202 - 656390 - - - -0.5887 - 1.88 0.377 - 65.6 3 2 0 -0.0007 11 0 0 0 4.62E+06 3.64E+06 - - - 3.3199 1 221125_WJC_METTL3_EV_vs_WT_F03.19014.19014.3 3.05E-07 18/72 R.LASTLVHLGEYQAAVDGAR[166.11].K "sp|Q00610|CLH1_HUMAN,tr|J3KS13|J3KS13_HUMAN,tr|A0A087WVQ6|A0A087WVQ6_HUMAN" 3 1980.0304 0.88 34074 19014 3 1980.026873 661.0174 Clathrin heavy chain 1 OS=Homo sapiens OX=9606 GN=CLTC PE=1 SV=5 5.32 3202.6 - 1.00E+07 - - - -1.7863 - 3.726 0.53 - 394.1 1 2 0 -0.0035 19 0 0 0 1.53E+08 1.73E+08 - - - 7.6795 0.9999 221125_WJC_METTL3_EV_vs_WT_F03.19015.19015.3 3.05E-08 14/64 R.IINEPTAAAIAYGLDKK[136.11].G "sp|P54652|HSP72_HUMAN,sp|P11142|HSP7C_HUMAN,tr|E9PKE3|E9PKE3_HUMAN,tr|E9PN89|E9PN89_HUMAN,tr|E9PI65|E9PI65_HUMAN" 5 1794.9971 - 34075 19015 3 1794.990729 599.3396 Heat shock-related 70 kDa protein 2 OS=Homo sapiens OX=9606 GN=HSPA2 PE=1 SV=1 6.07 3202.6 - 6.57E+06 - - - -3.5493 - 2.951 0.585 - 192 1 2 0 -0.0064 17 0 0 0 - - - - - 7.7942 1 221125_WJC_METTL3_EV_vs_WT_F03.19016.19016.3 8.17E-13 20/72 R.LASTLVHLGEYQAAVDGAR.K "sp|Q00610|CLH1_HUMAN,tr|J3KS13|J3KS13_HUMAN,tr|A0A087WVQ6|A0A087WVQ6_HUMAN" 3 1970.0221 0.88 34076 19016 3 1970.024932 657.6813 Clathrin heavy chain 1 OS=Homo sapiens OX=9606 GN=CLTC PE=1 SV=5 5.32 3202.6 - 7.40E+06 - - - 1.4172 - 3.524 0.634 - 567.6 1 2 0 0.0028 19 0 0 0 1.53E+08 1.73E+08 - - - 8.7023 0.9984 221125_WJC_METTL3_EV_vs_WT_F03.19017.19017.2 0.00806 20-Dec K.TIAQMIEDEQR.T "sp|O75410|TACC1_HUMAN,sp|O95359|TACC2_HUMAN,tr|E7EVI4|E7EVI4_HUMAN,tr|Q4VXL8|Q4VXL8_HUMAN,tr|Q4VXL4|Q4VXL4_HUMAN,tr|E7EMZ9|E7EMZ9_HUMAN,tr|H0Y9C3|H0Y9C3_HUMAN,tr|E9PBC6|E9PBC6_HUMAN,tr|E7ET87|E7ET87_HUMAN,tr|D6RAA5|D6RAA5_HUMAN" 10 1332.6344 1.15 34077 19017 2 1332.632256 667.3245 Transforming acidic coiled-coil-containing protein 1 OS=Homo sapiens OX=9606 GN=TACC1 PE=1 SV=2 4.14 3202.7 - 4.51E+06 - - - -1.5826 - 1.632 0.273 - 428.7 1 2 0 -0.0021 11 0 0 0 1.18E+08 1.03E+08 - - - 2.3818 1 221125_WJC_METTL3_EV_vs_WT_F03.19018.19018.2 1.77E-09 18/26 K.NPGVWLNTTQPLC[160.03]K[136.11].A "sp|O95983|MBD3_HUMAN,tr|K7EIE8|K7EIE8_HUMAN,tr|A0A0A0MTS6|A0A0A0MTS6_HUMAN" 3 1634.833 1.67 34078 19018 2 1634.830274 818.4238 Methyl-CpG-binding domain protein 3 OS=Homo sapiens OX=9606 GN=MBD3 PE=1 SV=1 8.22 3202.8 - 3.09E+06 - - - -1.6748 - 3.356 0.64 - 1147.9 1 2 0 -0.0027 14 0 0 0 2.10E+08 1.25E+08 - - - 6.8055 1 221125_WJC_METTL3_EV_vs_WT_F03.19020.19020.2 0.0225 17/28 Q.SVTDTNVILSMDNSR.N sp|P35908|K22E_HUMAN 1 1650.7883 20.76 34080 19020 2 1650.783604 826.4014 "Keratin, type II cytoskeletal 2 epidermal OS=Homo sapiens OX=9606 GN=KRT2 PE=1 SV=2" 4.21 3203 - 1.45E+06 - - - -2.8447 - 3.323 0.562 - 957.5 1 1 0 -0.0047 15 0 0 0 1.84E+07 8.85E+05 - - - 6.1428 1 221125_WJC_METTL3_EV_vs_WT_F03.19021.19021.2 1.71E-08 19/32 R.IINEPTAAAIAYGLDKK.G "sp|P54652|HSP72_HUMAN,sp|P11142|HSP7C_HUMAN,tr|E9PKE3|E9PKE3_HUMAN,tr|E9PN89|E9PN89_HUMAN,tr|E9PI65|E9PI65_HUMAN" 5 1786.9829 0.16 34081 19021 2 1786.981382 894.4987 Heat shock-related 70 kDa protein 2 OS=Homo sapiens OX=9606 GN=HSPA2 PE=1 SV=1 6.07 3203.1 - 1.31E+06 - - - -0.8495 - 3.667 0.614 - 926.5 1 2 0 -0.0015 17 0 0 0 8.90E+07 5.71E+08 - - - 6.7701 0.9997 221125_WJC_METTL3_EV_vs_WT_F03.19023.19023.2 0.00013 16/26 K.IAILTC[160.03]PFEPPKPK.T "sp|P48643|TCPE_HUMAN,tr|E9PCA1|E9PCA1_HUMAN,tr|B7ZAR1|B7ZAR1_HUMAN,tr|E7ENZ3|E7ENZ3_HUMAN" 4 1609.8902 0.64 34083 19023 2 1609.892904 805.9524 T-complex protein 1 subunit epsilon OS=Homo sapiens OX=9606 GN=CCT5 PE=1 SV=1 8.2 3203.4 - 961208 - - - 1.6883 - 2.514 0.413 - 800.2 1 2 0 0.0027 14 0 0 0 4.43E+07 6.96E+07 - - - 4.404 0.9955 221125_WJC_METTL3_EV_vs_WT_F03.19025.19025.2 0.299 18-Jun K.EHTANISWAM.- sp|Q15699|ALX1_HUMAN 1 1158.5128 - 34085 19025 2 1158.510678 580.2637 ALX homeobox protein 1 OS=Homo sapiens OX=9606 GN=ALX1 PE=1 SV=2 5.24 3203.6 - 307527 - - - -1.8256 - 1.1 0.319 - 57.9 1 2 0 -0.0021 10 0 0 0 - - - - - 1.6625 1 221125_WJC_METTL3_EV_vs_WT_F03.19027.19027.3 6.36E-05 15/52 K.IAILTC[160.03]PFEPPKPK.T "sp|P48643|TCPE_HUMAN,tr|E9PCA1|E9PCA1_HUMAN,tr|B7ZAR1|B7ZAR1_HUMAN,tr|E7ENZ3|E7ENZ3_HUMAN" 4 1609.8902 0.68 34086 19027 3 1609.888253 537.6373 T-complex protein 1 subunit epsilon OS=Homo sapiens OX=9606 GN=CCT5 PE=1 SV=1 8.2 3203.9 - 3.82E+07 - - - -1.2007 - 2.774 0.509 - 295.6 1 2 0 -0.0019 14 0 0 0 1.06E+09 1.56E+09 - - - 6.9258 0.9999 221125_WJC_METTL3_EV_vs_WT_F03.19029.19029.3 0.00399 14/36 R.VNILSDMHLR.S "sp|P51114|FXR1_HUMAN,tr|E7EU85|E7EU85_HUMAN,tr|E9PFF5|E9PFF5_HUMAN,tr|C9JZE0|C9JZE0_HUMAN,tr|C9JY20|C9JY20_HUMAN,tr|B4DXZ6|B4DXZ6_HUMAN" 6 1196.6336 1.46 34087 19029 3 1196.630724 399.8851 Fragile X mental retardation syndrome-related protein 1 OS=Homo sapiens OX=9606 GN=FXR1 PE=1 SV=3 6.71 3204.1 - 2.57E+06 - - - -2.3842 - 2.671 0.385 - 327.6 1 2 0 -0.0029 10 0 0 0 9.24E+07 6.32E+07 - - - 5.7008 0.9996 221125_WJC_METTL3_EV_vs_WT_F03.19030.19030.2 4.34E-05 15/24 R.ISTAIDDMEAYTK[136.11].L "sp|Q9Y3Z3|SAMH1_HUMAN,tr|A0A2R8YD90|A0A2R8YD90_HUMAN,tr|A0A2R8YCS7|A0A2R8YCS7_HUMAN" 3 1464.6898 0.52 34088 19030 2 1464.68696 733.3522 Deoxynucleoside triphosphate triphosphohydrolase SAMHD1 OS=Homo sapiens OX=9606 GN=SAMHD1 PE=1 SV=2 4.03 3204.2 - 1.20E+06 - - - -1.9124 - 1.85 0.462 - 561.7 1 2 0 -0.0028 13 0 0 0 6.16E+06 1.18E+07 - - - 4.0313 0.9957 221125_WJC_METTL3_EV_vs_WT_F03.19032.19032.3 0.472 14/40 K.KEGLSFLGGLR.S "sp|Q6WKZ4|RFIP1_HUMAN,tr|E7EX40|E7EX40_HUMAN" 2 1175.6663 1.13 34090 19032 3 1175.662172 392.896 Rab11 family-interacting protein 1 OS=Homo sapiens OX=9606 GN=RAB11FIP1 PE=1 SV=3 8.75 3204.5 - 1.69E+06 - - - -3.4755 - 2.511 0.206 - 204.4 1 2 0 -0.0041 11 0 0 0 2.03E+07 1.79E+07 - - - 3.4511 0.9115 221125_WJC_METTL3_EV_vs_WT_F03.19033.19033.2 2.75E-08 17/26 N.EPTAAAIAYGLDK[136.11]K[136.11].G "sp|P54652|HSP72_HUMAN,sp|P11142|HSP7C_HUMAN,tr|E9PKE3|E9PKE3_HUMAN,tr|E9PN89|E9PN89_HUMAN,tr|E9PI65|E9PI65_HUMAN" 5 1462.8002 0.13 34091 19033 2 1462.793016 732.4074 Heat shock-related 70 kDa protein 2 OS=Homo sapiens OX=9606 GN=HSPA2 PE=1 SV=1 6.17 3204.6 - 1.20E+06 - - - -4.9419 - 2.71 0.541 - 1014.8 1 1 0 -0.0072 14 0 0 0 3.15E+06 2.35E+07 - - - 5.5363 0.9996 221125_WJC_METTL3_EV_vs_WT_F03.19034.19034.2 0.0103 20-Oct K.NYPDPVSIIQK.Y "sp|P41252|SYIC_HUMAN,tr|A0A804HL54|A0A804HL54_HUMAN,tr|A0A804HKU1|A0A804HKU1_HUMAN,tr|A0A804HK69|A0A804HK69_HUMAN,tr|A0A804HIV9|A0A804HIV9_HUMAN,tr|A0A804HJN6|A0A804HJN6_HUMAN,tr|A0A804HHW9|A0A804HHW9_HUMAN,tr|A0A0A0MSX9|A0A0A0MSX9_HUMAN,tr|J3KR24|J3KR24_HUMAN,tr|A0A804HJ36|A0A804HJ36_HUMAN" 10 1272.6714 0.82 34092 19034 2 1272.671328 637.343 "Isoleucine--tRNA ligase, cytoplasmic OS=Homo sapiens OX=9606 GN=IARS1 PE=1 SV=2" 5.83 3204.7 - 1.28E+06 - - - -0.0589 - 1.695 0.393 - 238.4 1 2 0 -0.0001 11 0 0 0 3.35E+07 4.10E+07 - - - 3.3712 1 221125_WJC_METTL3_EV_vs_WT_F03.19036.19036.2 4.67E-06 13/26 K.NPGVWLNTTQPLC[160.03]K.A "sp|O95983|MBD3_HUMAN,tr|K7EIE8|K7EIE8_HUMAN,tr|A0A0A0MTS6|A0A0A0MTS6_HUMAN" 3 1626.8188 1.67 34093 19036 2 1626.816063 814.4167 Methyl-CpG-binding domain protein 3 OS=Homo sapiens OX=9606 GN=MBD3 PE=1 SV=1 8.22 3204.9 - 7.29E+06 - - - -1.6898 - 2.606 0.586 - 451.5 1 2 0 -0.0027 14 0 0 0 2.10E+08 1.25E+08 - - - 5.7719 0.9998 221125_WJC_METTL3_EV_vs_WT_F03.19038.19038.3 0.00112 13/36 R.VNILSDMHLR[166.11].S "sp|P51114|FXR1_HUMAN,tr|E7EU85|E7EU85_HUMAN,tr|E9PFF5|E9PFF5_HUMAN,tr|C9JZE0|C9JZE0_HUMAN,tr|C9JY20|C9JY20_HUMAN,tr|B4DXZ6|B4DXZ6_HUMAN" 6 1206.6418 1.46 34094 19038 3 1206.638372 403.2212 Fragile X mental retardation syndrome-related protein 1 OS=Homo sapiens OX=9606 GN=FXR1 PE=1 SV=3 6.71 3205.1 - 3.34E+06 - - - -2.8799 - 2.68 0.414 - 329.4 1 2 0 -0.0035 10 0 0 0 9.24E+07 6.32E+07 - - - 6.0337 1 221125_WJC_METTL3_EV_vs_WT_F03.19039.19039.2 0.000251 13/22 R.NTALTLAC[160.03]FQGR.T "sp|O75179|ANR17_HUMAN,sp|Q8IWZ3|ANKH1_HUMAN,tr|E9PDP5|E9PDP5_HUMAN,tr|H0YM23|H0YM23_HUMAN,tr|H3BLS9|H3BLS9_HUMAN,tr|H0YLQ3|H0YLQ3_HUMAN,tr|H7C2F5|H7C2F5_HUMAN" 7 1350.6714 1.63 34095 19039 2 1350.668725 676.343 Ankyrin repeat domain-containing protein 17 OS=Homo sapiens OX=9606 GN=ANKRD17 PE=1 SV=3 8.25 3205.2 - 3.32E+06 - - - -1.9953 - 2.665 0.58 - 664.1 1 2 0 -0.0027 12 0 0 0 1.02E+08 6.23E+07 - - - 5.9031 0.9997 221125_WJC_METTL3_EV_vs_WT_F03.19040.19040.2 7.51E-05 13/24 K.AGSFITGIDVTSK[136.11].E sp|Q53F19|NCBP3_HUMAN 1 1302.6911 1.23 34096 19040 2 1302.693027 652.3528 Nuclear cap-binding protein subunit 3 OS=Homo sapiens OX=9606 GN=NCBP3 PE=1 SV=2 5.88 3205.3 - 1.65E+06 - - - 1.4931 - 2.416 0.409 - 600.3 1 2 0 0.0019 13 0 0 0 5.07E+07 4.11E+07 - - - 4.3252 0.9997 221125_WJC_METTL3_EV_vs_WT_F03.19041.19041.3 0.00739 13/40 K.TIAQMIEDEQR.T "sp|O75410|TACC1_HUMAN,sp|O95359|TACC2_HUMAN,tr|E7EVI4|E7EVI4_HUMAN,tr|Q4VXL8|Q4VXL8_HUMAN,tr|Q4VXL4|Q4VXL4_HUMAN,tr|E7EMZ9|E7EMZ9_HUMAN,tr|H0Y9C3|H0Y9C3_HUMAN,tr|E9PBC6|E9PBC6_HUMAN,tr|E7ET87|E7ET87_HUMAN,tr|D6RAA5|D6RAA5_HUMAN" 10 1332.6344 1.06 34097 19041 3 1332.630583 445.2187 Transforming acidic coiled-coil-containing protein 1 OS=Homo sapiens OX=9606 GN=TACC1 PE=1 SV=2 4.14 3205.5 - 1.64E+06 - - - -2.838 - 2.302 0.402 - 278.3 1 2 0 -0.0038 11 0 0 0 1.55E+07 1.47E+07 - - - 5.3895 0.9999 221125_WJC_METTL3_EV_vs_WT_F03.19048.19048.3 0.00317 Oct-40 K.TIAQMIEDEQR[166.11].T "sp|O75410|TACC1_HUMAN,sp|O95359|TACC2_HUMAN,tr|E7EVI4|E7EVI4_HUMAN,tr|Q4VXL8|Q4VXL8_HUMAN,tr|Q4VXL4|Q4VXL4_HUMAN,tr|E7EMZ9|E7EMZ9_HUMAN,tr|H0Y9C3|H0Y9C3_HUMAN,tr|E9PBC6|E9PBC6_HUMAN,tr|E7ET87|E7ET87_HUMAN,tr|D6RAA5|D6RAA5_HUMAN" 10 1342.6426 1.04 34102 19048 3 1342.639491 448.5548 Transforming acidic coiled-coil-containing protein 1 OS=Homo sapiens OX=9606 GN=TACC1 PE=1 SV=2 4.14 3206.4 - 1.29E+06 - - - -2.3417 - 2.25 0.456 - 237.9 1 2 0 -0.0031 11 0 0 0 1.56E+07 1.49E+07 - - - 5.9268 0.9998 221125_WJC_METTL3_EV_vs_WT_F03.19049.19049.3 1.78E-05 17/64 R.ALIAQLPSPAIDHEQLR.Q "sp|Q9UPN3|MACF1_HUMAN,tr|A0A804HL78|A0A804HL78_HUMAN,tr|H3BQK9|H3BQK9_HUMAN,tr|A0A7P0MQR8|A0A7P0MQR8_HUMAN,tr|H0Y390|H0Y390_HUMAN,tr|H3BPE1|H3BPE1_HUMAN,tr|A0A590UJG2|A0A590UJG2_HUMAN" 7 1871.0265 11.52 34103 19049 3 1871.020283 624.6828 "Microtubule-actin cross-linking factor 1, isoforms 1\2\3\5 OS=Homo sapiens OX=9606 GN=MACF1 PE=1 SV=4" 5.32 3206.5 - 1.00E+06 - - - -3.3212 - 2.988 0.41 - 416.4 1 2 0 -0.0062 17 0 0 0 1.95E+07 1.69E+06 - - - 5.8747 1 221125_WJC_METTL3_EV_vs_WT_F03.19052.19052.3 9.09E-07 16/56 K.LEIAGTVVGHWAGSR[166.11].R "sp|Q9NZB2|F120A_HUMAN,tr|A0A0C4DG79|A0A0C4DG79_HUMAN,tr|A0A494C0Y9|A0A494C0Y9_HUMAN" 3 1561.824 0.8 34104 19052 3 1561.821765 521.6153 Constitutive coactivator of PPAR-gamma-like protein 1 OS=Homo sapiens OX=9606 GN=FAM120A PE=1 SV=2 6.75 3206.9 - 1.11E+06 - - - -1.4598 - 3.307 0.481 - 341.6 1 2 0 -0.0023 15 0 0 0 1.36E+07 1.71E+07 - - - 7.023 1 221125_WJC_METTL3_EV_vs_WT_F03.19053.19053.2 1.13E-08 18/32 R.GALTVGITNTVGSSISR[166.11].E "sp|Q06210|GFPT1_HUMAN,tr|A0A6I8PRN4|A0A6I8PRN4_HUMAN,tr|A0A6I8PTT9|A0A6I8PTT9_HUMAN" 3 1641.8925 1.08 34105 19053 2 1641.896673 821.9535 Glutamine--fructose-6-phosphate aminotransferase [isomerizing] 1 OS=Homo sapiens OX=9606 GN=GFPT1 PE=1 SV=3 9.75 3207 - 1.94E+06 - - - 2.53 - 3.352 0.579 - 761.9 1 2 0 0.0042 17 0 0 0 4.68E+07 4.35E+07 - - - 6.2899 0.9928 221125_WJC_METTL3_EV_vs_WT_F03.19054.19054.2 2.46E-05 15/26 Q.ISETNVILSMDNNR.S sp|P04264|K2C1_HUMAN 1 1604.7828 7.52 34106 19054 2 1604.781646 803.3987 "Keratin, type II cytoskeletal 1 OS=Homo sapiens OX=9606 GN=KRT1 PE=1 SV=6" 4.37 3207.1 - 4.46E+06 - - - -0.7316 - 2.512 0.497 - 670.8 1 1 0 -0.0012 14 0 0 0 1.09E+08 1.45E+07 - - - 5.0229 1 221125_WJC_METTL3_EV_vs_WT_F03.19056.19056.2 6.65E-06 15/22 R.NTALTLAC[160.03]FQGR[166.11].T "sp|O75179|ANR17_HUMAN,sp|Q8IWZ3|ANKH1_HUMAN,tr|E9PDP5|E9PDP5_HUMAN,tr|H0YM23|H0YM23_HUMAN,tr|H3BLS9|H3BLS9_HUMAN,tr|H0YLQ3|H0YLQ3_HUMAN,tr|H7C2F5|H7C2F5_HUMAN" 7 1360.6797 1.63 34108 19056 2 1360.672609 681.3471 Ankyrin repeat domain-containing protein 17 OS=Homo sapiens OX=9606 GN=ANKRD17 PE=1 SV=3 8.25 3207.3 - 3.01E+06 - - - -5.204 - 3.047 0.583 - 932.4 1 2 0 -0.0071 12 0 0 0 1.02E+08 6.23E+07 - - - 6.2764 0.9752 221125_WJC_METTL3_EV_vs_WT_F03.19060.19060.2 0.000758 24-Sep K.AEDTISILPDDPR.Q "sp|Q8WUH1|CHUR_HUMAN,tr|H0YIM9|H0YIM9_HUMAN,tr|A0A0C4DGJ7|A0A0C4DGJ7_HUMAN" 3 1440.7096 1.86 34110 19060 2 1440.69983 721.3621 Protein Churchill OS=Homo sapiens OX=9606 GN=CHURC1 PE=1 SV=2 3.84 3207.7 - 1.40E+06 - - - -6.8085 - 1.584 0.419 - 147.1 1 2 0 -0.0098 13 0 0 0 2.71E+07 1.46E+07 - - - 3.3131 0.9997 221125_WJC_METTL3_EV_vs_WT_F03.19061.19061.2 0.000382 24-Nov K.LC[160.03]SLFYTNEEVAK[136.11].N "sp|P43243|MATR3_HUMAN,tr|B3KM87|B3KM87_HUMAN,tr|A8MXP9|A8MXP9_HUMAN,tr|A0A0R4J2E8|A0A0R4J2E8_HUMAN" 4 1580.7636 1.38 34111 19061 2 1580.760954 791.3891 Matrin-3 OS=Homo sapiens OX=9606 GN=MATR3 PE=1 SV=2 4.53 3207.8 - 1.46E+06 - - - -1.6707 - 2.113 0.46 - 439.3 1 2 0 -0.0026 13 0 0 0 7.35E+07 5.33E+07 - - - 4.3578 0.9998 221125_WJC_METTL3_EV_vs_WT_F03.19063.19063.2 4.43E-05 24-Dec K.AGSFITGIDVTSK.E sp|Q53F19|NCBP3_HUMAN 1 1294.6769 1.23 34113 19063 2 1294.676001 648.3457 Nuclear cap-binding protein subunit 3 OS=Homo sapiens OX=9606 GN=NCBP3 PE=1 SV=2 5.88 3208 - 2.53E+06 - - - -0.6805 - 2.359 0.427 - 385.9 1 2 0 -0.0009 13 0 0 0 5.07E+07 4.11E+07 - - - 4.3972 0.9999 221125_WJC_METTL3_EV_vs_WT_F03.19067.19067.3 2.30E-09 20/60 K.RIPSIVSSPLNSPLDR.S sp|P49790|NU153_HUMAN 1 1749.9737 1.6 34115 19067 3 1749.967707 584.3319 Nuclear pore complex protein Nup153 OS=Homo sapiens OX=9606 GN=NUP153 PE=1 SV=2 9.6 3208.5 - 3.39E+06 - - - -3.4435 - 3.803 0.544 - 582.9 1 2 0 -0.006 16 0 0 0 8.57E+07 5.37E+07 - - - 8.0309 0.997 221125_WJC_METTL3_EV_vs_WT_F03.19068.19068.2 0.00508 16/26 R.MGLEVIPVTSTTNK[136.11].L "sp|Q6UN15|FIP1_HUMAN,tr|A0A0B4J203|A0A0B4J203_HUMAN" 2 1496.8 0.75 34116 19068 2 1496.793327 749.4073 Pre-mRNA 3'-end-processing factor FIP1 OS=Homo sapiens OX=9606 GN=FIP1L1 PE=1 SV=1 5.75 3208.6 - 1.65E+06 - - - -4.4448 - 2.791 0.308 - 785.3 1 2 0 -0.0067 14 0 0 0 2.82E+07 3.78E+07 - - - 3.8895 0.9997 221125_WJC_METTL3_EV_vs_WT_F03.19069.19069.2 0.000294 24-Dec R.QALVEFENIDSAK[136.11].E "sp|Q8WVV9|HNRLL_HUMAN,tr|V9GYK2|V9GYK2_HUMAN,tr|C9IYN3|C9IYN3_HUMAN,tr|B7WPG3|B7WPG3_HUMAN,tr|C9JJZ7|C9JJZ7_HUMAN,tr|H7BXH8|H7BXH8_HUMAN" 6 1470.7446 0.15 34117 19069 2 1470.743344 736.3796 Heterogeneous nuclear ribonucleoprotein L-like OS=Homo sapiens OX=9606 GN=HNRNPLL PE=1 SV=1 4.14 3208.7 - 1.31E+06 - - - -0.8363 - 2.176 0.355 - 470.9 1 2 0 -0.0012 13 0 0 0 3.66E+06 2.44E+07 - - - 3.6581 0.9988 221125_WJC_METTL3_EV_vs_WT_F03.19070.19070.2 2.44E-07 15/32 R.IINEPTAAAIAYGLDK[136.11]K.G "sp|P54652|HSP72_HUMAN,sp|P11142|HSP7C_HUMAN,tr|E9PKE3|E9PKE3_HUMAN,tr|E9PN89|E9PN89_HUMAN,tr|E9PI65|E9PI65_HUMAN" 5 1794.9971 - 34118 19070 2 1794.989469 898.5058 Heat shock-related 70 kDa protein 2 OS=Homo sapiens OX=9606 GN=HSPA2 PE=1 SV=1 6.07 3208.9 - 956225 - - - -4.2513 - 2.647 0.492 - 298.6 1 2 0 -0.0076 17 0 0 0 - - - - - 5.0657 0.9998 221125_WJC_METTL3_EV_vs_WT_F03.19074.19074.2 7.36E-05 22-Nov R.EIFGLYGQTTGK.G "sp|Q9NR31|SAR1A_HUMAN,tr|H0Y5E8|H0Y5E8_HUMAN" 2 1312.6663 0.79 34120 19074 2 1312.66393 657.3404 GTP-binding protein SAR1a OS=Homo sapiens OX=9606 GN=SAR1A PE=1 SV=1 6.1 3209.4 - 2.28E+07 - - - -1.8184 - 2.345 0.507 - 364.8 1 2 0 -0.0024 12 0 0 0 5.23E+08 6.59E+08 - - - 5.0275 0.9999 221125_WJC_METTL3_EV_vs_WT_F03.19075.19075.2 1.69E-05 13/22 K.EQFLDGDGWTSR.W "sp|P27797|CALR_HUMAN,tr|A0A7P0T861|A0A7P0T861_HUMAN,tr|K7EL50|K7EL50_HUMAN,tr|K7EJB9|K7EJB9_HUMAN" 4 1409.6212 1.28 34121 19075 2 1409.621688 705.8179 Calreticulin OS=Homo sapiens OX=9606 GN=CALR PE=1 SV=1 4.03 3209.5 - 1.83E+06 - - - 0.376 - 2.339 0.598 - 709.6 1 2 0 0.0005 12 0 0 0 3.02E+07 2.35E+07 - - - 5.6934 1 221125_WJC_METTL3_EV_vs_WT_F03.19076.19076.2 0.000264 19/30 R.VNTSEGVVLLSYSGQK.T sp|Q96T58|MINT_HUMAN 1 1679.873 1.31 34122 19076 2 1679.875375 840.9438 Msx2-interacting protein OS=Homo sapiens OX=9606 GN=SPEN PE=1 SV=1 5.97 3209.6 - 2.29E+06 - - - 1.4043 - 3.779 0.569 - 1218.6 1 2 0 0.0024 16 0 0 0 2.45E+07 1.87E+07 - - - 6.5114 0.9998 221125_WJC_METTL3_EV_vs_WT_F03.19077.19077.2 2.43E-08 18/30 K.TVEGAGSIAAATGFVK.K "sp|P37840|SYUA_HUMAN,tr|A0A669KB41|A0A669KB41_HUMAN,tr|A0A669KBH5|A0A669KBH5_HUMAN,tr|H6UYS7|H6UYS7_HUMAN,tr|E7EPV7|E7EPV7_HUMAN" 5 1477.7777 1.62 34123 19077 2 1477.775101 739.8961 Alpha-synuclein OS=Homo sapiens OX=9606 GN=SNCA PE=1 SV=1 5.66 3209.8 - 1.54E+06 - - - -1.731 - 2.61 0.555 - 518.5 1 2 0 -0.0026 16 0 0 0 4.35E+08 2.68E+08 - - - 5.498 0.9999 221125_WJC_METTL3_EV_vs_WT_F03.19078.19078.3 0.0068 16/48 R.QLQGFPFYGK[136.11]PMR[166.11].L sp|P08579|RU2B_HUMAN 1 1585.8194 1.41 34124 19078 3 1585.816413 529.6138 U2 small nuclear ribonucleoprotein B'' OS=Homo sapiens OX=9606 GN=SNRPB2 PE=1 SV=1 9.99 3209.9 - 955365 - - - -1.8987 - 2.629 0.383 - 360.6 1 2 0 -0.003 13 0 0 0 2.79E+07 1.97E+07 - - - 5.43 0.9993 221125_WJC_METTL3_EV_vs_WT_F03.19080.19080.3 0.00152 Nov-52 K.VLEQLTGQTPVFSK.A "sp|P62913|RL11_HUMAN,tr|Q5VVC8|Q5VVC8_HUMAN" 2 1545.8403 1.22 34125 19080 3 1545.837283 516.2874 60S ribosomal protein L11 OS=Homo sapiens OX=9606 GN=RPL11 PE=1 SV=2 5.97 3210.1 - 3.28E+06 - - - -1.9252 - 2.109 0.314 - 182.7 1 2 0 -0.003 14 0 0 0 6.96E+08 5.71E+08 - - - 4.0231 0.9996 221125_WJC_METTL3_EV_vs_WT_F03.19082.19082.2 2.01E-05 24-Oct K.LC[160.03]SLFYTNEEVAK.N "sp|P43243|MATR3_HUMAN,tr|B3KM87|B3KM87_HUMAN,tr|A8MXP9|A8MXP9_HUMAN,tr|A0A0R4J2E8|A0A0R4J2E8_HUMAN" 4 1572.7494 1.38 34126 19082 2 1572.744823 787.382 Matrin-3 OS=Homo sapiens OX=9606 GN=MATR3 PE=1 SV=2 4.53 3210.4 - 4.30E+06 - - - -2.907 - 2.369 0.528 - 389.4 1 2 0 -0.0046 13 0 0 0 7.35E+07 5.33E+07 - - - 5.1529 1 221125_WJC_METTL3_EV_vs_WT_F03.19083.19083.2 1.46E-06 18/32 R.GALTVGITNTVGSSISR.E "sp|Q06210|GFPT1_HUMAN,tr|A0A6I8PRN4|A0A6I8PRN4_HUMAN,tr|A0A6I8PTT9|A0A6I8PTT9_HUMAN" 3 1631.8842 1.08 34127 19083 2 1631.878604 816.9494 Glutamine--fructose-6-phosphate aminotransferase [isomerizing] 1 OS=Homo sapiens OX=9606 GN=GFPT1 PE=1 SV=3 9.75 3210.4 - 3.25E+06 - - - -3.4592 - 3.32 0.604 - 850.9 1 2 0 -0.0056 17 0 0 0 4.62E+07 4.30E+07 - - - 6.4505 0.9993 221125_WJC_METTL3_EV_vs_WT_F03.19084.19084.2 0.0008 22-Nov K.EQFLDGDGWTSR[166.11].W "sp|P27797|CALR_HUMAN,tr|A0A7P0T861|A0A7P0T861_HUMAN,tr|K7EL50|K7EL50_HUMAN,tr|K7EJB9|K7EJB9_HUMAN" 4 1419.6294 1.28 34128 19084 2 1419.624338 710.822 Calreticulin OS=Homo sapiens OX=9606 GN=CALR PE=1 SV=1 4.03 3210.5 - 1.94E+06 - - - -3.5854 - 2.188 0.539 - 488.1 1 2 0 -0.0051 12 0 0 0 3.02E+07 2.35E+07 - - - 5.0806 0.9999 221125_WJC_METTL3_EV_vs_WT_F03.19085.19085.2 6.86E-06 13/34 K.ENVATTDTLESTTVGTSV.- sp|Q15046|SYK_HUMAN 1 1823.8636 - 34129 19085 2 1823.863381 912.9391 Lysine--tRNA ligase OS=Homo sapiens OX=9606 GN=KARS1 PE=1 SV=3 3.57 3210.6 - 1.41E+06 - - - -0.1382 - 2.126 0.538 - 377.9 1 2 0 -0.0003 18 0 0 0 - - - - - 4.8689 0.9996 221125_WJC_METTL3_EV_vs_WT_F03.19086.19086.2 0.000174 20-Sep K.NYPDPVSIIQK.Y "sp|P41252|SYIC_HUMAN,tr|A0A804HL54|A0A804HL54_HUMAN,tr|A0A804HKU1|A0A804HKU1_HUMAN,tr|A0A804HK69|A0A804HK69_HUMAN,tr|A0A804HIV9|A0A804HIV9_HUMAN,tr|A0A804HJN6|A0A804HJN6_HUMAN,tr|A0A804HHW9|A0A804HHW9_HUMAN,tr|A0A0A0MSX9|A0A0A0MSX9_HUMAN,tr|J3KR24|J3KR24_HUMAN,tr|A0A804HJ36|A0A804HJ36_HUMAN" 10 1272.6714 0.82 34130 19086 2 1272.671471 637.343 "Isoleucine--tRNA ligase, cytoplasmic OS=Homo sapiens OX=9606 GN=IARS1 PE=1 SV=2" 5.83 3210.8 - 1.38E+06 - - - 0.0534 - 1.586 0.4 - 198.8 1 2 0 0.0001 11 0 0 0 3.35E+07 4.10E+07 - - - 3.2431 1 221125_WJC_METTL3_EV_vs_WT_F03.19087.19087.2 3.25E-10 17/32 R.SVGDGETVEFDVVEGEK.G "sp|Q9Y2T7|YBOX2_HUMAN,sp|P67809|YBOX1_HUMAN,sp|P16989|YBOX3_HUMAN,tr|H0Y449|H0Y449_HUMAN,tr|A0A0D9SEI8|A0A0D9SEI8_HUMAN" 5 1794.816 1.16 34131 19087 2 1794.810386 898.4153 Y-box-binding protein 2 OS=Homo sapiens OX=9606 GN=YBX2 PE=1 SV=2 3.77 3210.9 - 1.37E+06 - - - -3.1023 - 3.316 0.685 - 688.5 1 2 0 -0.0056 17 0 0 0 1.14E+08 9.78E+07 - - - 7.0459 0.9999 221125_WJC_METTL3_EV_vs_WT_F03.19088.19088.3 2.77E-05 14/64 R.GALTVGITNTVGSSISR[166.11].E "sp|Q06210|GFPT1_HUMAN,tr|A0A6I8PRN4|A0A6I8PRN4_HUMAN,tr|A0A6I8PTT9|A0A6I8PTT9_HUMAN" 3 1641.8925 0.22 34132 19088 3 1641.890711 548.3048 Glutamine--fructose-6-phosphate aminotransferase [isomerizing] 1 OS=Homo sapiens OX=9606 GN=GFPT1 PE=1 SV=3 9.75 3211 - 1.21E+06 - - - -1.1012 - 2.823 0.423 - 187.9 1 2 0 -0.0018 17 0 0 0 5.29E+06 2.36E+07 - - - 5.8773 0.9408 221125_WJC_METTL3_EV_vs_WT_F03.19090.19090.2 0.000185 13/26 N.AVVTVPAYFNDSQR.Q "sp|P11142|HSP7C_HUMAN,tr|E9PQQ4|E9PQQ4_HUMAN,tr|E9PN89|E9PN89_HUMAN,tr|E9PLF4|E9PLF4_HUMAN,tr|E9PI65|E9PI65_HUMAN,tr|E9PK54|E9PK54_HUMAN,tr|E9PQK7|E9PQK7_HUMAN" 7 1565.7838 0.35 34134 19090 2 1565.789112 783.8992 Heat shock cognate 71 kDa protein OS=Homo sapiens OX=9606 GN=HSPA8 PE=1 SV=1 5.88 3211.2 - 795101 - - - 3.3881 - 2.164 0.449 - 315.2 1 1 0 0.0053 14 0 0 0 9.20E+06 2.63E+07 - - - 4.2928 0.9996 221125_WJC_METTL3_EV_vs_WT_F03.19096.19096.2 0.0111 16-Aug K.DEVYQILEK.G "sp|P52732|KIF11_HUMAN,tr|A0A7I2YQY4|A0A7I2YQY4_HUMAN,tr|A0A7I2V3A9|A0A7I2V3A9_HUMAN,tr|A0A7I2V3V3|A0A7I2V3V3_HUMAN" 4 1135.5761 7.85 34138 19096 2 1135.574581 568.7953 Kinesin-like protein KIF11 OS=Homo sapiens OX=9606 GN=KIF11 PE=1 SV=2 4.14 3211.9 - 4.27E+06 - - - -1.3421 - 1.838 0.388 - 266.5 1 2 0 -0.0015 9 0 0 0 4.13E+07 5.26E+06 - - - 3.6672 1 221125_WJC_METTL3_EV_vs_WT_F03.19097.19097.3 1.70E-08 16/44 R.FDDVWPMDPHPR.T "sp|O00165|HAX1_HUMAN,tr|E9PIQ7|E9PIQ7_HUMAN" 2 1510.6663 1.18 34139 19097 3 1510.66661 504.5627 HCLS1-associated protein X-1 OS=Homo sapiens OX=9606 GN=HAX1 PE=1 SV=2 4.41 3212 - 2.16E+06 - - - 0.1827 - 2.633 0.6 - 322.9 1 2 0 0.0003 12 0 0 0 2.75E+07 2.32E+07 - - - 7.9128 1 221125_WJC_METTL3_EV_vs_WT_F03.19098.19098.3 2.27E-08 14/68 K.QITSYGETC[160.03]PGLEQYAIK[136.11].K sp|P50990|TCPQ_HUMAN 1 2064.9918 0.34 34140 19098 3 2064.989944 689.3379 T-complex protein 1 subunit theta OS=Homo sapiens OX=9606 GN=CCT8 PE=1 SV=4 4.53 3212.1 - 4.04E+06 - - - -0.878 - 3.036 0.593 - 231.6 1 2 0 -0.0018 18 0 0 0 1.71E+07 5.11E+07 - - - 7.9162 1 221125_WJC_METTL3_EV_vs_WT_F03.19099.19099.3 0.00028 Nov-44 R.FLQDYFDGNLK[136.11]R[166.11].Y sp|P30101|PDIA3_HUMAN 1 1532.7742 0.59 34141 19099 3 1532.772558 511.932 Protein disulfide-isomerase A3 OS=Homo sapiens OX=9606 GN=PDIA3 PE=1 SV=4 5.96 3212.1 - 2.92E+06 - - - -1.1026 - 2.202 0.47 - 101.4 1 2 0 -0.0017 12 0 0 0 2.40E+07 4.05E+07 - - - 5.9676 1 221125_WJC_METTL3_EV_vs_WT_F03.19100.19100.2 4.48E-10 16/34 K.QITSYGETC[160.03]PGLEQYAIK[136.11].K sp|P50990|TCPQ_HUMAN 1 2064.9918 0.34 34142 19100 2 2064.990499 1033.5032 T-complex protein 1 subunit theta OS=Homo sapiens OX=9606 GN=CCT8 PE=1 SV=4 4.53 3212.2 - 2.36E+06 - - - -0.6092 - 3.023 0.632 - 571.1 1 2 0 -0.0013 18 0 0 0 1.00E+07 2.94E+07 - - - 6.4283 0.9999 221125_WJC_METTL3_EV_vs_WT_F03.19101.19101.3 2.20E-05 16/44 R.FDDVWPMDPHPR[166.11].T "sp|O00165|HAX1_HUMAN,tr|E9PIQ7|E9PIQ7_HUMAN" 2 1520.6746 1.19 34143 19101 3 1520.669307 507.8988 HCLS1-associated protein X-1 OS=Homo sapiens OX=9606 GN=HAX1 PE=1 SV=2 4.41 3212.3 - 2.27E+06 - - - -3.4833 - 2.374 0.634 - 343.3 1 2 0 -0.0053 12 0 0 0 2.76E+07 2.32E+07 - - - 8.0035 0.9999 221125_WJC_METTL3_EV_vs_WT_F03.19102.19102.3 4.64E-07 14/60 K.TVEGAGSIAAATGFVK[136.11].K "sp|P37840|SYUA_HUMAN,tr|A0A669KB41|A0A669KB41_HUMAN,tr|A0A669KBH5|A0A669KBH5_HUMAN,tr|H6UYS7|H6UYS7_HUMAN,tr|E7EPV7|E7EPV7_HUMAN" 5 1485.7919 1.6 34144 19102 3 1485.788771 496.2712 Alpha-synuclein OS=Homo sapiens OX=9606 GN=SNCA PE=1 SV=1 5.66 3212.4 - 2.09E+06 - - - -2.0784 - 2.372 0.491 - 233.3 1 2 0 -0.0031 16 0 0 0 8.09E+07 5.05E+07 - - - 6.2295 1 221125_WJC_METTL3_EV_vs_WT_F03.19103.19103.3 2.28E-08 18/60 K.R[166.11]IPSIVSSPLNSPLDR[166.11].S sp|P49790|NU153_HUMAN 1 1769.9903 1.6 34145 19103 3 1769.989608 591.004 Nuclear pore complex protein Nup153 OS=Homo sapiens OX=9606 GN=NUP153 PE=1 SV=2 9.6 3212.4 - 1.88E+06 - - - -0.3757 - 2.903 0.493 - 327.5 1 2 0 -0.0007 16 0 0 0 8.57E+07 5.37E+07 - - - 6.7708 0.9999 221125_WJC_METTL3_EV_vs_WT_F03.19104.19104.3 3.65E-07 15/44 R.YTDR[166.11]DFYFASIR[166.11].R sp|L0R8F8|MIDUO_HUMAN 1 1572.7476 0.97 34146 19104 3 1572.746513 525.2565 MIEF1 upstream open reading frame protein OS=Homo sapiens OX=9606 GN=MIEF1 PE=1 SV=1 5.96 3212.5 - 1.87E+06 - - - -0.6803 - 2.6 0.515 - 281 1 2 1 -0.0011 12 0 0 0 3.87E+07 3.98E+07 - - - 6.93 0.9997 221125_WJC_METTL3_EV_vs_WT_F03.19105.19105.2 6.65E-07 15/26 K.GAVYSFDPVGSYQR[166.11].D sp|P20618|PSB1_HUMAN 1 1554.7342 0.93 34147 19105 2 1554.730357 778.3744 Proteasome subunit beta type-1 OS=Homo sapiens OX=9606 GN=PSMB1 PE=1 SV=2 5.83 3212.6 - 1.74E+06 - - - -2.4892 - 2.677 0.568 - 556.7 1 2 0 -0.0039 14 0 0 0 1.78E+07 1.91E+07 - - - 5.7061 0.9675 221125_WJC_METTL3_EV_vs_WT_F03.19107.19107.2 1.20E-05 13/34 K.VVGSAVGSGSITSNIVAS.N "sp|Q9Y5A9|YTHD2_HUMAN,tr|S4R3V3|S4R3V3_HUMAN" 2 1603.8417 - 34149 19107 2 1603.846402 802.9281 YTH domain-containing family protein 2 OS=Homo sapiens OX=9606 GN=YTHDF2 PE=1 SV=2 5.49 3212.9 - 1.43E+06 - - - 2.9224 - 2.449 0.475 - 427.7 1 1 0 0.0047 18 0 0 0 - - - - - 4.7499 1 221125_WJC_METTL3_EV_vs_WT_F03.19108.19108.2 1.09E-07 17/30 K.VTNGAFTGEISPGMIK.D sp|P60174|TPIS_HUMAN 1 1620.8181 1.61 34150 19108 2 1620.816277 811.4163 Triosephosphate isomerase OS=Homo sapiens OX=9606 GN=TPI1 PE=1 SV=4 5.97 3213 - 1.38E+06 - - - -1.1513 - 2.929 0.599 - 928.8 1 2 0 -0.0019 16 0 0 0 8.43E+06 5.25E+06 - - - 6.1067 1 221125_WJC_METTL3_EV_vs_WT_F03.19109.19109.2 2.49E-06 14/22 R.IAEEVNC[160.03]LLAC[160.03]R.D "sp|Q6KC79|NIPBL_HUMAN,tr|A0A590UJS4|A0A590UJS4_HUMAN" 2 1446.6959 1.34 34151 19109 2 1446.695359 724.3552 Nipped-B-like protein OS=Homo sapiens OX=9606 GN=NIPBL PE=1 SV=2 4.53 3213.1 - 1.35E+06 - - - -0.3878 - 3.01 0.524 - 995.4 1 2 0 -0.0006 12 0 0 0 8.25E+06 6.16E+06 - - - 5.8105 0.9998 221125_WJC_METTL3_EV_vs_WT_F03.19111.19111.3 1.11E-05 15/44 R.YTDRDFYFASIR.R sp|L0R8F8|MIDUO_HUMAN 1 1552.731 0.77 34153 19111 3 1552.729399 518.5843 MIEF1 upstream open reading frame protein OS=Homo sapiens OX=9606 GN=MIEF1 PE=1 SV=1 5.96 3213.3 - 1.24E+06 - - - -1.0588 - 2.49 0.473 - 280.8 1 2 1 -0.0016 12 0 0 0 4.65E+07 6.04E+07 - - - 6.3417 0.9996 221125_WJC_METTL3_EV_vs_WT_F03.19112.19112.2 1.52E-05 14/24 R.NVQSVSIIDTELK[136.11].V "sp|Q15645|PCH2_HUMAN,tr|H0YAL2|H0YAL2_HUMAN" 2 1452.7915 1.01 34154 19112 2 1452.794678 727.403 Pachytene checkpoint protein 2 homolog OS=Homo sapiens OX=9606 GN=TRIP13 PE=1 SV=2 4.37 3213.4 - 986229 - - - 2.171 - 2.22 0.452 - 552.5 1 2 0 0.0032 13 0 0 0 1.84E+07 1.83E+07 - - - 4.4253 0.9995 221125_WJC_METTL3_EV_vs_WT_F03.19114.19114.3 3.77E-05 15/44 R.MVILLC[160.03]NLKPAK.M "sp|Q12904|AIMP1_HUMAN,tr|A0A804HJ47|A0A804HJ47_HUMAN,tr|A0A5F9ZHC5|A0A5F9ZHC5_HUMAN" 3 1398.8091 0.89 34156 19114 3 1398.815152 467.277 Aminoacyl tRNA synthase complex-interacting multifunctional protein 1 OS=Homo sapiens OX=9606 GN=AIMP1 PE=1 SV=2 9.31 3213.7 - 818517 - - - 4.3273 - 2.872 0.402 - 275 1 2 0 0.0061 12 0 0 0 1.04E+07 1.17E+07 - - - 5.9446 0.9875 221125_WJC_METTL3_EV_vs_WT_F03.19115.19115.2 2.94E-08 20-Nov R.NPEAALSPTFR[166.11].S "sp|Q86U44|MTA70_HUMAN,tr|B4E349|B4E349_HUMAN,tr|F5H6D8|F5H6D8_HUMAN,tr|B4DTN4|B4DTN4_HUMAN" 4 1211.6174 0.001 34157 19115 2 1211.607496 606.816 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 6 3213.8 - 782686 - - - -8.18 - 2.541 0.525 - 426.5 1 2 0 -0.0099 11 0 0 0 0.00E+00 2.05E+07 - - - 5.4383 0.9999 221125_WJC_METTL3_EV_vs_WT_F03.19119.19119.2 9.31E-05 14/30 K.TVEGAGSIAAATGFVK[136.11].K "sp|P37840|SYUA_HUMAN,tr|A0A669KB41|A0A669KB41_HUMAN,tr|A0A669KBH5|A0A669KBH5_HUMAN,tr|H6UYS7|H6UYS7_HUMAN,tr|E7EPV7|E7EPV7_HUMAN" 5 1485.7919 1.64 34160 19119 2 1485.791188 743.9032 Alpha-synuclein OS=Homo sapiens OX=9606 GN=SNCA PE=1 SV=1 5.66 3214.2 - 2.45E+07 - - - -0.4516 - 2.888 0.495 - 347 1 2 0 -0.0007 16 0 0 0 4.47E+08 2.73E+08 - - - 5.3043 1 221125_WJC_METTL3_EV_vs_WT_F03.19122.19122.3 2.07E-08 19/68 K.QITSYGETC[160.03]PGLEQYAIK.K sp|P50990|TCPQ_HUMAN 1 2056.9776 0.34 34163 19122 3 2056.977361 686.6665 T-complex protein 1 subunit theta OS=Homo sapiens OX=9606 GN=CCT8 PE=1 SV=4 4.53 3214.4 - 2.86E+06 - - - -0.0953 - 3.579 0.618 - 440.1 1 2 0 -0.0002 18 0 0 0 1.71E+07 5.11E+07 - - - 8.6051 0.9997 221125_WJC_METTL3_EV_vs_WT_F03.19123.19123.2 4.39E-07 14/26 K.GAVYSFDPVGSYQR.D sp|P20618|PSB1_HUMAN 1 1544.726 0.93 34164 19123 2 1544.730024 773.3703 Proteasome subunit beta type-1 OS=Homo sapiens OX=9606 GN=PSMB1 PE=1 SV=2 5.83 3214.4 - 2.69E+06 - - - 2.6328 - 2.63 0.573 - 473.9 1 2 0 0.0041 14 0 0 0 1.78E+07 1.91E+07 - - - 5.6985 1 221125_WJC_METTL3_EV_vs_WT_F03.19127.19127.2 9.36E-13 20/34 K.QITSYGETC[160.03]PGLEQYAIK.K sp|P50990|TCPQ_HUMAN 1 2056.9776 0.34 34168 19127 2 2056.977364 1029.4961 T-complex protein 1 subunit theta OS=Homo sapiens OX=9606 GN=CCT8 PE=1 SV=4 4.53 3214.8 - 1.26E+06 - - - -0.0938 - 3.537 0.7 - 975.1 1 2 0 -0.0002 18 0 0 0 1.00E+07 2.91E+07 - - - 7.317 1 221125_WJC_METTL3_EV_vs_WT_F03.19128.19128.3 4.40E-07 18/60 K.LLSPVVPQISAPQSNK.E "sp|Q8N1F7|NUP93_HUMAN,tr|H3BRD9|H3BRD9_HUMAN,tr|H3BVG0|H3BVG0_HUMAN,tr|H3BVE2|H3BVE2_HUMAN" 4 1676.9461 2.7 34169 19128 3 1676.947913 559.9893 Nuclear pore complex protein Nup93 OS=Homo sapiens OX=9606 GN=NUP93 PE=1 SV=2 8.75 3215 - 1.18E+06 - - - 1.0686 - 2.666 0.483 - 359.4 1 2 0 0.0018 16 0 0 0 4.58E+06 1.70E+06 - - - 6.4405 0.9982 221125_WJC_METTL3_EV_vs_WT_F03.19129.19129.3 0.00125 Nov-40 K.SC[160.03]LLLQFTDKR.F "sp|P61019|RAB2A_HUMAN,sp|Q8WUD1|RAB2B_HUMAN,tr|A0A3B3ITL1|A0A3B3ITL1_HUMAN,tr|E9PE37|E9PE37_HUMAN,tr|E9PKL7|E9PKL7_HUMAN,tr|H0YDL5|H0YDL5_HUMAN,tr|H0YD31|H0YD31_HUMAN" 7 1379.7231 1.68 34170 19129 3 1379.727042 460.915 Ras-related protein Rab-2A OS=Homo sapiens OX=9606 GN=RAB2A PE=1 SV=1 7.94 3215.1 - 1.13E+06 - - - 2.8419 - 2.327 0.256 - 105.5 1 2 0 0.0039 11 0 0 0 1.25E+07 7.49E+06 - - - 3.7924 0.9998 221125_WJC_METTL3_EV_vs_WT_F03.19130.19130.2 0.00212 16-Sep K.DEVYQILEK[136.11].G "sp|P52732|KIF11_HUMAN,tr|A0A7I2YQY4|A0A7I2YQY4_HUMAN,tr|A0A7I2V3A9|A0A7I2V3A9_HUMAN,tr|A0A7I2V3V3|A0A7I2V3V3_HUMAN" 4 1143.5903 7.78 34171 19130 2 1143.589985 572.8024 Kinesin-like protein KIF11 OS=Homo sapiens OX=9606 GN=KIF11 PE=1 SV=2 4.14 3215.2 - 1.01E+06 - - - -0.2798 - 1.819 0.413 - 311.2 1 2 0 -0.0003 9 0 0 0 4.09E+07 5.26E+06 - - - 3.8222 0.9985 221125_WJC_METTL3_EV_vs_WT_F03.19134.19134.3 0.00143 Dec-52 K.FK[136.11]GPFTDVVTTNLK[136.11].L sp|Q9P0L0|VAPA_HUMAN 1 1581.8737 1.4 34175 19134 3 1581.874434 528.2985 Vesicle-associated membrane protein-associated protein A OS=Homo sapiens OX=9606 GN=VAPA PE=1 SV=3 8.59 3215.7 - 764668 - - - 0.4362 - 2.335 0.302 - 128.8 1 2 1 0.0007 14 0 0 0 1.38E+07 9.85E+06 - - - 4.1604 0.999 221125_WJC_METTL3_EV_vs_WT_F03.19136.19136.2 0.00915 22-Sep K.STLQTLPEIVAK.E sp|O95202|LETM1_HUMAN 1 1298.7446 1.98 34177 19136 2 1298.743413 650.3796 Mitochondrial proton\calcium exchanger protein OS=Homo sapiens OX=9606 GN=LETM1 PE=1 SV=1 5.72 3216 - 677809 - - - -0.8893 - 1.683 0.282 - 291.2 1 2 0 -0.0012 12 0 0 0 4.80E+06 2.42E+06 - - - 2.4932 1 221125_WJC_METTL3_EV_vs_WT_F03.19138.19138.3 4.66E-11 19/60 R.LPAAGVGDMVMATVK[136.11]K[136.11].G "sp|P62829|RL23_HUMAN,tr|J3KT29|J3KT29_HUMAN,tr|B9ZVP7|B9ZVP7_HUMAN,tr|C9JD32|C9JD32_HUMAN" 4 1602.8808 0.74 34178 19138 3 1602.883774 535.3009 60S ribosomal protein L23 OS=Homo sapiens OX=9606 GN=RPL23 PE=1 SV=1 8.59 3216.3 - 1.49E+06 - - - 1.8429 - 3.361 0.596 - 407.5 1 2 0 0.003 16 0 0 0 2.69E+07 3.65E+07 - - - 8.2944 0.9998 221125_WJC_METTL3_EV_vs_WT_F03.19139.19139.2 0.000236 16-Sep R.NLFNVVDC[160.03]K.L sp|P55884|EIF3B_HUMAN 1 1107.5383 0.68 34179 19139 2 1107.53801 554.7764 Eukaryotic translation initiation factor 3 subunit B OS=Homo sapiens OX=9606 GN=EIF3B PE=1 SV=3 5.83 3216.4 - 417154 - - - -0.2438 - 1.863 0.428 - 194.6 1 2 0 -0.0003 9 0 0 0 2.70E+06 3.96E+06 - - - 4.0021 0.9999 221125_WJC_METTL3_EV_vs_WT_F03.19145.19145.2 7.20E-05 15/22 R.GTVTDFPGFDER.A "sp|P08758|ANXA5_HUMAN,tr|E9PHT9|E9PHT9_HUMAN,tr|D6RBE9|D6RBE9_HUMAN,tr|D6RCN3|D6RCN3_HUMAN" 4 1339.6044 1.32 34185 19145 2 1339.604742 670.8095 Annexin A5 OS=Homo sapiens OX=9606 GN=ANXA5 PE=1 SV=2 4.03 3217 - 933364 - - - 0.2217 - 2.939 0.517 - 872.2 1 2 0 0.0003 12 0 0 0 4.97E+06 3.78E+06 - - - 5.6961 0.9978 221125_WJC_METTL3_EV_vs_WT_F03.19146.19146.3 0.0232 Dec-40 K.YSTLSLFDKYK.G "sp|Q5JSZ5|PRC2B_HUMAN,tr|A0A804HKL6|A0A804HKL6_HUMAN" 2 1363.7024 0.43 34186 19146 3 1363.70393 455.5747 Protein PRRC2B OS=Homo sapiens OX=9606 GN=PRRC2B PE=1 SV=2 8.43 3217.1 - 886850 - - - 1.1454 - 2.013 0.31 - 120 1 2 1 0.0016 11 0 0 0 5.18E+06 1.21E+07 - - - 3.9833 1 221125_WJC_METTL3_EV_vs_WT_F03.19147.19147.3 0.000661 15/44 R.MVILLC[160.03]NLK[136.11]PAK[136.11].M "sp|Q12904|AIMP1_HUMAN,tr|A0A804HJ47|A0A804HJ47_HUMAN,tr|A0A5F9ZHC5|A0A5F9ZHC5_HUMAN" 3 1414.8375 0.87 34187 19147 3 1414.837895 472.6198 Aminoacyl tRNA synthase complex-interacting multifunctional protein 1 OS=Homo sapiens OX=9606 GN=AIMP1 PE=1 SV=2 9.31 3217.2 - 883894 - - - 0.2799 - 2.98 0.424 - 301.6 1 2 0 0.0004 12 0 0 0 1.02E+07 1.17E+07 - - - 6.2937 1 221125_WJC_METTL3_EV_vs_WT_F03.19148.19148.2 1.18E-10 17/30 K.LLSPVVPQISAPQSNK.E "sp|Q8N1F7|NUP93_HUMAN,tr|H3BRD9|H3BRD9_HUMAN,tr|H3BVG0|H3BVG0_HUMAN,tr|H3BVE2|H3BVE2_HUMAN" 4 1676.9461 2.89 34188 19148 2 1676.944153 839.4803 Nuclear pore complex protein Nup93 OS=Homo sapiens OX=9606 GN=NUP93 PE=1 SV=2 8.75 3217.3 - 869804 - - - -1.1736 - 2.954 0.625 - 669.7 1 2 0 -0.002 16 0 0 0 8.89E+06 3.08E+06 - - - 6.3196 0.9998 221125_WJC_METTL3_EV_vs_WT_F03.19149.19149.2 2.02E-05 22-Nov R.GTVTDFPGFDER[166.11].A "sp|P08758|ANXA5_HUMAN,tr|E9PHT9|E9PHT9_HUMAN,tr|D6RBE9|D6RBE9_HUMAN,tr|D6RCN3|D6RCN3_HUMAN" 4 1349.6127 1.32 34189 19149 2 1349.611238 675.8136 Annexin A5 OS=Homo sapiens OX=9606 GN=ANXA5 PE=1 SV=2 4.03 3217.4 - 747173 - - - -1.0944 - 2.132 0.489 - 495.4 1 2 0 -0.0015 12 0 0 0 4.97E+06 3.78E+06 - - - 4.6442 1 221125_WJC_METTL3_EV_vs_WT_F03.19150.19150.3 0.000181 Dec-36 R.DLELPDMHMR.D "sp|Q8IXK0|PHC2_HUMAN,tr|A0A0A0MSI2|A0A0A0MSI2_HUMAN,tr|B3KPJ4|B3KPJ4_HUMAN" 3 1255.5689 1.39 34190 19150 3 1255.568342 419.5303 Polyhomeotic-like protein 2 OS=Homo sapiens OX=9606 GN=PHC2 PE=1 SV=1 4.54 3217.6 - 739453 - - - -0.4667 - 2.126 0.478 - 229.7 1 2 0 -0.0006 10 0 0 0 7.99E+06 5.74E+06 - - - 6.0718 0.9926 221125_WJC_METTL3_EV_vs_WT_F03.19154.19154.2 0.00957 24-Aug K.GGSSPETLPSLLK.R "sp|Q9UPN3|MACF1_HUMAN,tr|H3BQK9|H3BQK9_HUMAN,tr|A0A7P0MQR8|A0A7P0MQR8_HUMAN,tr|E9PNZ4|E9PNZ4_HUMAN,tr|H0Y390|H0Y390_HUMAN,tr|H3BPE1|H3BPE1_HUMAN,tr|A0A590UJG2|A0A590UJG2_HUMAN" 7 1284.6925 -1 34194 19154 2 1284.688591 643.3535 "Microtubule-actin cross-linking factor 1, isoforms 1\2\3\5 OS=Homo sapiens OX=9606 GN=MACF1 PE=1 SV=4" 6 3218.1 - 473367 - - - -3.0677 - 1.411 0.279 - 171.8 1 2 0 -0.0039 13 0 0 0 0.00E+00 0.00E+00 - - - 1.9841 0.9971 221125_WJC_METTL3_EV_vs_WT_F03.19155.19155.3 0.019 Sep-36 R.SLGVHLSFIR[166.11].S "sp|Q9NP61|ARFG3_HUMAN,sp|Q8N6H7|ARFG2_HUMAN,tr|E9PMU9|E9PMU9_HUMAN,tr|B0QYV9|B0QYV9_HUMAN,tr|E9PNY8|E9PNY8_HUMAN,tr|H0YDX1|H0YDX1_HUMAN,tr|E9PIY6|E9PIY6_HUMAN,tr|E9PQP3|E9PQP3_HUMAN,tr|E9PJT7|E9PJT7_HUMAN,tr|B0QYV8|B0QYV8_HUMAN,tr|E9PMR9|E9PMR9_HUMAN,tr|E9PN48|E9PN48_HUMAN,tr|E9PK28|E9PK28_HUMAN,tr|E9PM63|E9PM63_HUMAN,tr|G5E9L0|G5E9L0_HUMAN,tr|A0A0D9SF70|A0A0D9SF70_HUMAN" 16 1137.6534 0.001 34195 19155 3 1137.650519 380.2251 ADP-ribosylation factor GTPase-activating protein 3 OS=Homo sapiens OX=9606 GN=ARFGAP3 PE=1 SV=1 9.49 3218.2 - 376464 - - - -2.5306 - 1.57 0.305 - 96.4 1 2 0 -0.0029 10 0 0 0 0.00E+00 3.59E+06 - - - 3.257 0.789 221125_WJC_METTL3_EV_vs_WT_F03.19156.19156.3 0.333 Sep-60 R.SAYDSTMETMNYAQIR[166.11].T sp|P53396|ACLY_HUMAN 1 1889.8163 1.02 34196 19156 3 1889.811232 630.946 ATP-citrate synthase OS=Homo sapiens OX=9606 GN=ACLY PE=1 SV=3 4.37 3218.3 - 348177 - - - -2.6918 - 1.33 0.116 - 41.9 1 2 0 -0.0051 16 0 0 0 1.94E+06 1.90E+06 - - - 0.5636 0.9696 221125_WJC_METTL3_EV_vs_WT_F03.19157.19157.3 0.00296 13/40 R.LKDLEALLNSK.E "sp|P02545|LMNA_HUMAN,tr|A0A6Q8PF80|A0A6Q8PF80_HUMAN,tr|A0A804HL68|A0A804HL68_HUMAN,tr|Q5TCI8|Q5TCI8_HUMAN,tr|A0A6Q8PFJ0|A0A6Q8PFJ0_HUMAN,tr|A0A6Q8PHQ9|A0A6Q8PHQ9_HUMAN,tr|A0A6Q8PGH0|A0A6Q8PGH0_HUMAN,tr|Q3BDU5|Q3BDU5_HUMAN" 8 1242.7184 1.72 34197 19157 3 1242.714327 415.2467 Prelamin-A\C OS=Homo sapiens OX=9606 GN=LMNA PE=1 SV=1 6.07 3218.4 - 345195 - - - -3.2397 - 2.283 0.191 - 200.1 1 2 1 -0.004 11 0 0 0 1.06E+07 6.20E+06 - - - 3.0134 1 221125_WJC_METTL3_EV_vs_WT_F03.19160.19160.2 8.36E-09 19/36 K.VGDGDLSAEEIPENEVSLR.R sp|Q14684|RRP1B_HUMAN 1 2027.9647 -1 34199 19160 2 2027.967292 1014.9896 Ribosomal RNA processing protein 1 homolog B OS=Homo sapiens OX=9606 GN=RRP1B PE=1 SV=3 3.77 3218.8 - 295793 - - - 1.2564 - 2.991 0.615 - 623.1 1 2 0 0.0025 19 0 0 0 0.00E+00 0.00E+00 - - - 6.2762 1 221125_WJC_METTL3_EV_vs_WT_F03.19161.19161.2 6.36E-09 15/32 R.SVGDGETVEFDVVEGEK[136.11].G "sp|Q9Y2T7|YBOX2_HUMAN,sp|P67809|YBOX1_HUMAN,sp|P16989|YBOX3_HUMAN,tr|H0Y449|H0Y449_HUMAN,tr|A0A0D9SEI8|A0A0D9SEI8_HUMAN" 5 1802.8302 1.14 34200 19161 2 1802.829224 902.4224 Y-box-binding protein 2 OS=Homo sapiens OX=9606 GN=YBX2 PE=1 SV=2 3.77 3218.8 - 1.35E+07 - - - -0.5159 - 3.259 0.691 - 551.8 1 2 0 -0.0009 17 0 0 0 1.08E+08 9.44E+07 - - - 7.049 0.9999 221125_WJC_METTL3_EV_vs_WT_F03.19163.19163.2 2.70E-06 18-Oct R.GYFEYIEENK[136.11].Y "sp|Q00839|HNRPU_HUMAN,tr|Q5RI18|Q5RI18_HUMAN,tr|A0A1W2PP35|A0A1W2PP35_HUMAN,tr|A0A1W2PPS1|A0A1W2PPS1_HUMAN,tr|A0A1W2PRI6|A0A1W2PRI6_HUMAN" 5 1298.591 1.05 34202 19163 2 1298.590743 650.3028 Heterogeneous nuclear ribonucleoprotein U OS=Homo sapiens OX=9606 GN=HNRNPU PE=1 SV=6 4.25 3218.9 - 3.28E+06 - - - -0.2233 - 2.218 0.493 - 317.7 1 2 0 -0.0003 10 0 0 0 8.00E+08 7.62E+08 - - - 4.9058 0.9997 221125_WJC_METTL3_EV_vs_WT_F03.19164.19164.2 1.08E-05 18-Sep R.GYFEYIEENK.Y "sp|Q00839|HNRPU_HUMAN,tr|Q5RI18|Q5RI18_HUMAN,tr|A0A1W2PP35|A0A1W2PP35_HUMAN,tr|A0A1W2PPS1|A0A1W2PPS1_HUMAN,tr|A0A1W2PRI6|A0A1W2PRI6_HUMAN" 5 1290.5768 1.05 34203 19164 2 1290.577015 646.2957 Heterogeneous nuclear ribonucleoprotein U OS=Homo sapiens OX=9606 GN=HNRNPU PE=1 SV=6 4.25 3219 - 3.02E+06 - - - 0.141 - 1.918 0.392 - 213 1 2 0 0.0002 10 0 0 0 8.00E+08 7.62E+08 - - - 3.7542 0.9999 221125_WJC_METTL3_EV_vs_WT_F03.19165.19165.3 0.00037 16/44 R.TRLGLDDFESLK.V "sp|Q9Y2H1|ST38L_HUMAN,tr|F5GY51|F5GY51_HUMAN,tr|I3L0D0|I3L0D0_HUMAN,tr|F5H7Z3|F5H7Z3_HUMAN" 4 1392.7249 2.06 34204 19165 3 1392.725352 465.2489 Serine\threonine-protein kinase 38-like OS=Homo sapiens OX=9606 GN=STK38L PE=1 SV=3 4.56 3219.1 - 3.01E+06 - - - 0.3281 - 2.9 0.491 - 407.1 1 2 1 0.0005 12 0 0 0 1.60E+07 7.79E+06 - - - 6.9653 1 221125_WJC_METTL3_EV_vs_WT_F03.19166.19166.2 2.41E-07 13/24 K.NYSPYYNTIDDLK.D sp|P35527|K1C9_HUMAN 1 1604.7359 9.97 34205 19166 2 1604.736022 803.3752 "Keratin, type I cytoskeletal 9 OS=Homo sapiens OX=9606 GN=KRT9 PE=1 SV=3" 4.21 3219.1 - 2.97E+06 - - - 0.1053 - 2.73 0.647 - 599 1 2 0 0.0002 13 0 0 0 1.22E+08 1.22E+07 - - - 6.3973 1 221125_WJC_METTL3_EV_vs_WT_F03.19167.19167.3 5.29E-09 21/64 K.AFVAIGDYNGHVGLGVK[136.11].C "sp|P15880|RS2_HUMAN,tr|I3L404|I3L404_HUMAN,tr|E9PM36|E9PM36_HUMAN,tr|E9PPT0|E9PPT0_HUMAN,tr|E9PMM9|E9PMM9_HUMAN,tr|H0YEN5|H0YEN5_HUMAN" 6 1723.9137 1.01 34206 19167 3 1723.914108 575.6452 40S ribosomal protein S2 OS=Homo sapiens OX=9606 GN=RPS2 PE=1 SV=2 6.79 3219.2 - 2.15E+06 - - - 0.2338 - 3.96 0.645 - 512.5 1 2 0 0.0004 17 0 0 0 1.15E+08 1.14E+08 - - - 9.2078 1 221125_WJC_METTL3_EV_vs_WT_F03.19168.19168.3 8.17E-07 16/48 R.VFIGNLNTLVVK[136.11]K[136.11].S "sp|P0DMR1|HNRC4_HUMAN,sp|P07910|HNRPC_HUMAN,sp|O60812|HNRC1_HUMAN,sp|B2RXH8|HNRC2_HUMAN,sp|B7ZW38|HNRC3_HUMAN,tr|G3V251|G3V251_HUMAN,tr|B4DY08|B4DY08_HUMAN,tr|G3V575|G3V575_HUMAN,tr|B4DSU6|B4DSU6_HUMAN,tr|G3V3K6|G3V3K6_HUMAN,tr|B2R5W2|B2R5W2_HUMAN,tr|G3V4C1|G3V4C1_HUMAN,tr|A0A0G2JPF8|A0A0G2JPF8_HUMAN,tr|A0A0G2JNQ3|A0A0G2JNQ3_HUMAN,tr|G3V576|G3V576_HUMAN,tr|G3V5X6|G3V5X6_HUMAN,tr|G3V2H6|G3V2H6_HUMAN,tr|G3V4W0|G3V4W0_HUMAN,tr|G3V555|G3V555_HUMAN,tr|G3V4M8|G3V4M8_HUMAN,tr|G3V2Q1|G3V2Q1_HUMAN" 21 1459.9097 1.35 34207 19168 3 1459.910329 487.6439 Heterogeneous nuclear ribonucleoprotein C-like 4 OS=Homo sapiens OX=9606 GN=HNRNPCL4 PE=3 SV=1 10 3219.3 - 1.79E+06 - - - 0.4062 - 3.037 0.53 - 259.8 1 2 0 0.0006 13 0 0 0 4.21E+07 3.12E+07 - - - 7.4607 0.9995 221125_WJC_METTL3_EV_vs_WT_F03.19169.19169.3 0.000531 Nov-56 K.IIPLYSTLPPQQQQR.L sp|O43143|DHX15_HUMAN 1 1780.9836 1.94 34208 19169 3 1780.98459 594.6685 Pre-mRNA-splicing factor ATP-dependent RNA helicase DHX15 OS=Homo sapiens OX=9606 GN=DHX15 PE=1 SV=2 8.75 3219.3 - 1.78E+06 - - - 0.5733 - 1.968 0.318 - 147.7 1 2 0 0.001 15 0 0 0 4.79E+07 2.46E+07 - - - 3.8517 1 221125_WJC_METTL3_EV_vs_WT_F03.19171.19171.3 0.000259 19/48 R.VFIGNLNTLVVKK.S "sp|P0DMR1|HNRC4_HUMAN,sp|P07910|HNRPC_HUMAN,sp|O60812|HNRC1_HUMAN,sp|B2RXH8|HNRC2_HUMAN,sp|B7ZW38|HNRC3_HUMAN,tr|G3V251|G3V251_HUMAN,tr|B4DY08|B4DY08_HUMAN,tr|G3V575|G3V575_HUMAN,tr|B4DSU6|B4DSU6_HUMAN,tr|G3V3K6|G3V3K6_HUMAN,tr|B2R5W2|B2R5W2_HUMAN,tr|G3V4C1|G3V4C1_HUMAN,tr|A0A0G2JPF8|A0A0G2JPF8_HUMAN,tr|A0A0G2JNQ3|A0A0G2JNQ3_HUMAN,tr|G3V576|G3V576_HUMAN,tr|G3V5X6|G3V5X6_HUMAN,tr|G3V2H6|G3V2H6_HUMAN,tr|G3V4W0|G3V4W0_HUMAN,tr|G3V555|G3V555_HUMAN,tr|G3V4M8|G3V4M8_HUMAN,tr|G3V2Q1|G3V2Q1_HUMAN" 21 1443.8813 1.35 34210 19171 3 1443.881599 482.3011 Heterogeneous nuclear ribonucleoprotein C-like 4 OS=Homo sapiens OX=9606 GN=HNRNPCL4 PE=3 SV=1 10 3219.5 - 1.72E+06 - - - 0.1821 - 3.404 0.593 - 343.9 1 2 0 0.0003 13 0 0 0 4.19E+07 3.10E+07 - - - 8.4725 1 221125_WJC_METTL3_EV_vs_WT_F03.19173.19173.3 0.000121 13/36 R.DLELPDMHMR[166.11].D "sp|Q8IXK0|PHC2_HUMAN,tr|A0A0A0MSI2|A0A0A0MSI2_HUMAN,tr|B3KPJ4|B3KPJ4_HUMAN" 3 1265.5772 1.39 34212 19173 3 1265.576129 422.8663 Polyhomeotic-like protein 2 OS=Homo sapiens OX=9606 GN=PHC2 PE=1 SV=1 4.54 3219.7 - 1.01E+06 - - - -0.8447 - 2.147 0.49 - 270.9 1 2 0 -0.0011 10 0 0 0 7.99E+06 5.74E+06 - - - 6.2341 0.9981 221125_WJC_METTL3_EV_vs_WT_F03.19174.19174.2 1.24E-05 13/22 R.QVSASLLFSC[160.03]SK.D "sp|Q6W2J9|BCOR_HUMAN,tr|H7C2V9|H7C2V9_HUMAN,tr|H7C231|H7C231_HUMAN" 3 1325.6649 0.82 34213 19174 2 1325.660814 663.8397 BCL-6 corepressor OS=Homo sapiens OX=9606 GN=BCOR PE=1 SV=1 8.22 3219.8 - 1.09E+06 - - - -3.1101 - 2.22 0.29 - 483.6 1 2 0 -0.0041 12 0 0 0 6.88E+06 8.41E+06 - - - 3.28 0.9438 221125_WJC_METTL3_EV_vs_WT_F03.19175.19175.2 0.192 24-May R.MYVNNMPDLNVC[160.03]K.R "sp|Q9NSY1|BMP2K_HUMAN,tr|K4DI97|K4DI97_HUMAN" 2 1596.7099 -1 34214 19175 2 1596.70442 799.3622 BMP-2-inducible protein kinase OS=Homo sapiens OX=9606 GN=BMP2K PE=1 SV=2 5.58 3219.9 - 777704 - - - -3.4039 - 1.065 0.194 - 72 1 2 0 -0.0054 13 0 0 0 0.00E+00 0.00E+00 - - - 0.6338 0.9631 221125_WJC_METTL3_EV_vs_WT_F03.19176.19176.3 0.00183 Nov-56 L.VGLFEDTNLC[160.03]AIHAK.R "sp|Q5TEC6|H3PS2_HUMAN,sp|P84243|H33_HUMAN,sp|Q71DI3|H32_HUMAN,sp|P68431|H31_HUMAN,tr|K7EK07|K7EK07_HUMAN,tr|A0A590UJL8|A0A590UJL8_HUMAN" 6 1686.8399 -1 34215 19176 3 1686.844606 563.2873 Histone HIST2H3PS2 OS=Homo sapiens OX=9606 GN=H3-2 PE=1 SV=1 5.32 3220 - 768074 - - - 2.7649 - 2.106 0.413 - 106.4 1 1 0 0.0047 15 0 0 0 0.00E+00 0.00E+00 - - - 5.0867 0.9999 221125_WJC_METTL3_EV_vs_WT_F03.19182.19182.3 1.23E-08 23/68 R.IIAFVGSPVEDNEK[136.11]DLVK[136.11].L "sp|P55036|PSMD4_HUMAN,tr|A6PVX3|A6PVX3_HUMAN,tr|Q5VWC4|Q5VWC4_HUMAN" 3 1988.0801 1.22 34220 19182 3 1988.079378 663.7006 26S proteasome non-ATPase regulatory subunit 4 OS=Homo sapiens OX=9606 GN=PSMD4 PE=1 SV=1 4.32 3220.7 - 2.76E+06 - - - -0.3672 - 3.703 0.536 - 547.3 1 2 1 -0.0007 18 0 0 0 9.10E+07 7.46E+07 - - - 7.7756 1 221125_WJC_METTL3_EV_vs_WT_F03.19183.19183.2 4.04E-05 18/26 K.NVALLSQLYHSPAR.R sp|Q15717|ELAV1_HUMAN 1 1567.8471 1.52 34221 19183 2 1567.847532 784.9308 ELAV-like protein 1 OS=Homo sapiens OX=9606 GN=ELAVL1 PE=1 SV=2 8.75 3220.8 - 2.50E+06 - - - 0.2908 - 3.178 0.599 - 1154.7 1 2 0 0.0005 14 0 0 0 3.16E+07 2.08E+07 - - - 6.3666 0.9999 221125_WJC_METTL3_EV_vs_WT_F03.19184.19184.2 0.0149 13/22 R.NQLTAMSSVLAK.A sp|Q14152|EIF3A_HUMAN 1 1261.67 1.22 34222 19184 2 1261.670697 631.8423 Eukaryotic translation initiation factor 3 subunit A OS=Homo sapiens OX=9606 GN=EIF3A PE=1 SV=1 8.75 3220.9 - 1.80E+06 - - - 0.535 - 2.664 0.488 - 632 1 2 0 0.0007 12 0 0 0 7.80E+06 6.38E+06 - - - 5.2233 1 221125_WJC_METTL3_EV_vs_WT_F03.19185.19185.2 1.53E-07 18/28 R.ALEYTIYNQELNETR[166.11].A sp|Q9UQE7|SMC3_HUMAN 1 1865.9035 0.001 34223 19185 2 1865.901616 933.959 Structural maintenance of chromosomes protein 3 OS=Homo sapiens OX=9606 GN=SMC3 PE=1 SV=2 4.25 3221 - 1.75E+06 - - - -0.9979 - 3.133 0.59 - 1202 1 2 0 -0.0019 15 0 0 0 0.00E+00 1.24E+07 - - - 6.2058 0.9998 221125_WJC_METTL3_EV_vs_WT_F03.19186.19186.2 0.0231 14/22 R.NQLTAMSSVLAK[136.11].A sp|Q14152|EIF3A_HUMAN 1 1269.6842 1.22 34224 19186 2 1269.686185 635.8494 Eukaryotic translation initiation factor 3 subunit A OS=Homo sapiens OX=9606 GN=EIF3A PE=1 SV=1 8.75 3221.1 - 1.56E+06 - - - 1.5461 - 2.357 0.48 - 758.7 1 2 0 0.002 12 0 0 0 7.80E+06 6.38E+06 - - - 4.8416 1 221125_WJC_METTL3_EV_vs_WT_F03.19187.19187.3 3.25E-08 20/80 K.VLGENYTLEDEEDSQIC[160.03]TVGR.L sp|Q15029|U5S1_HUMAN 1 2426.0907 2.52 34225 19187 3 2426.091118 809.7042 116 kDa U5 small nuclear ribonucleoprotein component OS=Homo sapiens OX=9606 GN=EFTUD2 PE=1 SV=1 3.77 3221.2 - 1.51E+06 - - - 0.1521 - 3.909 0.672 - 308.8 1 2 0 0.0004 21 0 0 0 6.71E+06 2.66E+06 - - - 9.3004 0.9933 221125_WJC_METTL3_EV_vs_WT_F03.19188.19188.3 1.40E-05 Dec-56 L.VGLFEDTNLC[160.03]AIHAK[136.11].R "sp|Q5TEC6|H3PS2_HUMAN,sp|P84243|H33_HUMAN,sp|Q71DI3|H32_HUMAN,sp|P68431|H31_HUMAN,tr|K7EK07|K7EK07_HUMAN,tr|A0A590UJL8|A0A590UJL8_HUMAN" 6 1694.8541 0.71 34226 19188 3 1694.855884 565.9587 Histone HIST2H3PS2 OS=Homo sapiens OX=9606 GN=H3-2 PE=1 SV=1 5.32 3221.3 - 1.05E+06 - - - 1.0278 - 2.358 0.446 - 147.5 1 1 0 0.0017 15 0 0 0 2.51E+06 3.53E+06 - - - 5.7503 0.9999 221125_WJC_METTL3_EV_vs_WT_F03.19189.19189.2 0.0257 16/30 R.LLDAQLSTGGIVDPSK.S "sp|Q15149|PLEC_HUMAN,tr|H0YDN1|H0YDN1_HUMAN" 2 1612.8672 2.04 34227 19189 2 1612.866116 807.4409 Plectin OS=Homo sapiens OX=9606 GN=PLEC PE=1 SV=3 4.21 3221.4 - 905434 - - - -0.6733 - 3.164 0.506 - 778 1 2 0 -0.0011 16 0 0 0 1.56E+07 7.62E+06 - - - 5.6098 1 221125_WJC_METTL3_EV_vs_WT_F03.19190.19190.3 4.60E-10 20/80 K.VLGENYTLEDEEDSQIC[160.03]TVGR[166.11].L sp|Q15029|U5S1_HUMAN 1 2436.099 2.52 34228 19190 3 2436.091556 813.0403 116 kDa U5 small nuclear ribonucleoprotein component OS=Homo sapiens OX=9606 GN=EFTUD2 PE=1 SV=1 3.77 3221.6 - 904173 - - - -3.0635 - 3.295 0.6 - 411.7 1 2 0 -0.0075 21 0 0 0 6.71E+06 2.66E+06 - - - 8.0861 0.9994 221125_WJC_METTL3_EV_vs_WT_F03.19191.19191.2 0.00331 22-Sep K.STLQTLPEIVAK[136.11].E sp|O95202|LETM1_HUMAN 1 1306.7588 0.65 34229 19191 2 1306.758478 654.3867 Mitochondrial proton\calcium exchanger protein OS=Homo sapiens OX=9606 GN=LETM1 PE=1 SV=1 5.72 3221.7 - 854096 - - - -0.2219 - 1.668 0.342 - 231 1 2 0 -0.0003 12 0 0 0 3.13E+06 4.77E+06 - - - 2.9131 0.9995 221125_WJC_METTL3_EV_vs_WT_F03.19193.19193.2 0.00457 28-Dec K.IIPLYSTLPPQQQQR.L sp|O43143|DHX15_HUMAN 1 1780.9836 -1 34231 19193 2 1780.981718 891.4991 Pre-mRNA-splicing factor ATP-dependent RNA helicase DHX15 OS=Homo sapiens OX=9606 GN=DHX15 PE=1 SV=2 8.75 3222 - 669415 - - - -1.0393 - 1.808 0.373 - 184.2 1 2 0 -0.0019 15 0 0 0 0.00E+00 0.00E+00 - - - 3.2514 0.9953 221125_WJC_METTL3_EV_vs_WT_F03.19195.19195.2 1.27E-05 14/26 R.AGDAFGDTSFLNSK[136.11].A "sp|Q9H3Q1|BORG4_HUMAN,tr|J3KRZ9|J3KRZ9_HUMAN,tr|J3QQS6|J3QQS6_HUMAN" 3 1436.6663 3.53 34233 19195 2 1436.657253 719.3404 Cdc42 effector protein 4 OS=Homo sapiens OX=9606 GN=CDC42EP4 PE=1 SV=1 4.21 3222.2 - 717823 - - - -6.3139 - 2.335 0.553 - 602.4 1 2 0 -0.0091 14 0 0 0 1.11E+07 3.16E+06 - - - 5.2507 0.9824 221125_WJC_METTL3_EV_vs_WT_F03.19196.19196.2 0.244 16-Jul K.EGYENFFDK[136.11].L "sp|Q9H0P0|5NT3A_HUMAN,tr|B9A035|B9A035_HUMAN,tr|X6RM59|X6RM59_HUMAN" 3 1155.4964 1.43 34234 19196 2 1155.495391 578.7555 Cytosolic 5'-nucleotidase 3A OS=Homo sapiens OX=9606 GN=NT5C3A PE=1 SV=3 4.14 3222.3 - 565666 - - - -0.8775 - 0.903 0.214 - 77.1 1 2 0 -0.001 9 0 0 0 2.18E+06 1.52E+06 - - - 0.3261 0.9981 221125_WJC_METTL3_EV_vs_WT_F03.19197.19197.3 0.0116 Aug-36 R.GYFEYIEENK.Y "sp|Q00839|HNRPU_HUMAN,tr|Q5RI18|Q5RI18_HUMAN,tr|A0A1W2PP35|A0A1W2PP35_HUMAN,tr|A0A1W2PPS1|A0A1W2PPS1_HUMAN,tr|A0A1W2PRI6|A0A1W2PRI6_HUMAN" 5 1290.5768 1.06 34235 19197 3 1290.577088 431.1996 Heterogeneous nuclear ribonucleoprotein U OS=Homo sapiens OX=9606 GN=HNRNPU PE=1 SV=6 4.25 3222.5 - 544462 - - - 0.1976 - 1.62 0.26 - 77.3 1 2 0 0.0003 10 0 0 0 2.16E+07 2.03E+07 - - - 2.8476 0.9999 221125_WJC_METTL3_EV_vs_WT_F03.19203.19203.2 3.33E-06 20-Oct K.SFQGEIDALSK.R "sp|Q13948|CASP_HUMAN,sp|P39880|CUX1_HUMAN,tr|A0A2R8Y852|A0A2R8Y852_HUMAN,tr|A0A2R8YDI1|A0A2R8YDI1_HUMAN" 4 1193.5928 1.44 34240 19203 2 1193.59284 597.8037 Protein CASP OS=Homo sapiens OX=9606 GN=CUX1 PE=1 SV=2 4.37 3223.1 - 1.16E+07 - - - 0.0184 - 1.95 0.563 - 228.3 1 2 0 0 11 0 0 0 5.80E+07 4.02E+07 - - - 5.0059 0.9997 221125_WJC_METTL3_EV_vs_WT_F03.19206.19206.3 0.000806 13/40 R.AEVVSLLLDR[166.11]K[136.11].A "sp|Q8IWZ3|ANKH1_HUMAN,tr|E9PDP5|E9PDP5_HUMAN,tr|H3BLS9|H3BLS9_HUMAN,tr|H7C2F5|H7C2F5_HUMAN" 4 1259.7568 1.05 34243 19206 3 1259.754146 420.9262 Ankyrin repeat and KH domain-containing protein 1 OS=Homo sapiens OX=9606 GN=ANKHD1 PE=1 SV=1 6.11 3223.3 - 3.40E+06 - - - -2.1123 - 2.933 0.296 - 344.7 1 2 0 -0.0027 11 0 0 0 1.23E+07 1.17E+07 - - - 4.8962 0.9946 221125_WJC_METTL3_EV_vs_WT_F03.19208.19208.3 4.51E-07 Nov-64 M.R[166.11]IINEPTAAAIAYGLDK[136.11].R "sp|P11021|BIP_HUMAN,sp|P54652|HSP72_HUMAN,sp|P34931|HS71L_HUMAN,sp|P11142|HSP7C_HUMAN,tr|E9PKE3|E9PKE3_HUMAN,tr|E9PN89|E9PN89_HUMAN,tr|A0A7P0TB36|A0A7P0TB36_HUMAN,tr|E9PLF4|E9PLF4_HUMAN,tr|A0A7P0TAI0|A0A7P0TAI0_HUMAN,tr|Q53FA3|Q53FA3_HUMAN,tr|E9PI65|E9PI65_HUMAN" 11 1833.0115 0.75 34245 19208 3 1833.015935 612.0111 Endoplasmic reticulum chaperone BiP OS=Homo sapiens OX=9606 GN=HSPA5 PE=1 SV=2 6.07 3223.4 - 2.55E+06 - - - 2.4097 - 2.814 0.528 - 147.5 1 1 0 0.0044 17 0 0 0 5.62E+06 7.54E+06 - - - 7.0392 0.9998 221125_WJC_METTL3_EV_vs_WT_F03.19211.19211.2 2.32E-06 26-Nov R.AGDAFGDTSFLNSK.A "sp|Q9H3Q1|BORG4_HUMAN,tr|J3KRZ9|J3KRZ9_HUMAN,tr|J3QQS6|J3QQS6_HUMAN" 3 1428.6521 3.53 34248 19211 2 1428.652082 715.3333 Cdc42 effector protein 4 OS=Homo sapiens OX=9606 GN=CDC42EP4 PE=1 SV=1 4.21 3223.6 - 2.75E+06 - - - -0.0294 - 1.869 0.525 - 352.9 1 2 0 0 14 0 0 0 1.11E+07 3.16E+06 - - - 4.4881 0.9993 221125_WJC_METTL3_EV_vs_WT_F03.19212.19212.3 1.33 Nov-36 K.DRPFFPGLVK.Y "sp|O60361|NDK8_HUMAN,sp|P22392|NDKB_HUMAN,tr|Q32Q12|Q32Q12_HUMAN,tr|J3KPD9|J3KPD9_HUMAN,tr|F6XY72|F6XY72_HUMAN" 5 1174.6499 1.21 34249 19212 3 1174.648602 392.5572 Putative nucleoside diphosphate kinase OS=Homo sapiens OX=9606 GN=NME2P1 PE=5 SV=1 8.75 3223.6 - 1.94E+06 - - - -1.0871 - 1.906 0.288 - 150.5 1 2 0 -0.0013 10 0 0 0 3.03E+08 2.50E+08 - - - 3.6343 0.998 221125_WJC_METTL3_EV_vs_WT_F03.19214.19214.3 2.60E-05 19/64 M.RIINEPTAAAIAYGLDK.R "sp|P11021|BIP_HUMAN,sp|P54652|HSP72_HUMAN,sp|P34931|HS71L_HUMAN,sp|P11142|HSP7C_HUMAN,tr|E9PKE3|E9PKE3_HUMAN,tr|E9PN89|E9PN89_HUMAN,tr|A0A7P0TB36|A0A7P0TB36_HUMAN,tr|E9PLF4|E9PLF4_HUMAN,tr|A0A7P0TAI0|A0A7P0TAI0_HUMAN,tr|Q53FA3|Q53FA3_HUMAN,tr|E9PI65|E9PI65_HUMAN" 11 1814.989 0.75 34251 19214 3 1814.989483 606.0036 Endoplasmic reticulum chaperone BiP OS=Homo sapiens OX=9606 GN=HSPA5 PE=1 SV=2 6.07 3223.8 - 1.53E+06 - - - 0.2397 - 3.537 0.483 - 551.1 1 1 0 0.0004 17 0 0 0 6.91E+06 9.22E+06 - - - 7.1163 1 221125_WJC_METTL3_EV_vs_WT_F03.19215.19215.2 1.76E-07 24-Dec R.NADC[160.03]LAELNEAMR.G sp|Q8IU81|I2BP1_HUMAN 1 1505.6603 1.43 34252 19215 2 1505.657652 753.8374 Interferon regulatory factor 2-binding protein 1 OS=Homo sapiens OX=9606 GN=IRF2BP1 PE=1 SV=1 4.14 3223.8 - 1.50E+06 - - - -1.7341 - 2.652 0.65 - 511.3 1 2 0 -0.0026 13 0 0 0 7.99E+06 5.59E+06 - - - 6.3443 1 221125_WJC_METTL3_EV_vs_WT_F03.19216.19216.2 7.32E-08 16/32 K.AFVAIGDYNGHVGLGVK[136.11].C "sp|P15880|RS2_HUMAN,tr|I3L404|I3L404_HUMAN,tr|E9PM36|E9PM36_HUMAN,tr|E9PPT0|E9PPT0_HUMAN,tr|E9PMM9|E9PMM9_HUMAN,tr|H0YEN5|H0YEN5_HUMAN" 6 1723.9137 0.85 34253 19216 2 1723.914678 862.9641 40S ribosomal protein S2 OS=Homo sapiens OX=9606 GN=RPS2 PE=1 SV=2 6.79 3224 - 1.44E+06 - - - 0.5644 - 2.975 0.559 - 764.4 1 2 0 0.001 17 0 0 0 6.66E+06 7.84E+06 - - - 5.8499 0.8471 221125_WJC_METTL3_EV_vs_WT_F03.19219.19219.2 0.14 26-Oct R.VIPDFVC[160.03]QGGDITK[136.11].H sp|P49792|RBP2_HUMAN 1 1555.7796 0 34256 19219 2 1555.789528 778.8971 E3 SUMO-protein ligase RanBP2 OS=Homo sapiens OX=9606 GN=RANBP2 PE=1 SV=2 4.21 3224.3 - 1.30E+06 - - - 6.3942 - 1.568 0.159 - 137.9 1 2 0 0.0099 14 0 0 0 3.33E+05 2.26E+08 - - - 1.341 1 221125_WJC_METTL3_EV_vs_WT_F03.19220.19220.2 6.12E-09 18/32 K.AFVAIGDYNGHVGLGVK.C "sp|P15880|RS2_HUMAN,tr|I3L404|I3L404_HUMAN,tr|E9PM36|E9PM36_HUMAN,tr|E9PPT0|E9PPT0_HUMAN,tr|E9PMM9|E9PMM9_HUMAN,tr|H0YEN5|H0YEN5_HUMAN" 6 1715.8995 0.85 34257 19220 2 1715.896945 858.957 40S ribosomal protein S2 OS=Homo sapiens OX=9606 GN=RPS2 PE=1 SV=2 6.79 3224.4 - 1.25E+06 - - - -1.4919 - 3.293 0.615 - 873.2 1 2 0 -0.0026 17 0 0 0 6.66E+06 7.84E+06 - - - 6.5127 1 221125_WJC_METTL3_EV_vs_WT_F03.19224.19224.3 1.33E-09 18/64 K.AFVAIGDYNGHVGLGVK.C "sp|P15880|RS2_HUMAN,tr|I3L404|I3L404_HUMAN,tr|E9PM36|E9PM36_HUMAN,tr|E9PPT0|E9PPT0_HUMAN,tr|E9PMM9|E9PMM9_HUMAN,tr|H0YEN5|H0YEN5_HUMAN" 6 1715.8995 1.01 34260 19224 3 1715.899601 572.9738 40S ribosomal protein S2 OS=Homo sapiens OX=9606 GN=RPS2 PE=1 SV=2 6.79 3224.8 - 2.55E+07 - - - 0.0559 - 3.442 0.671 - 333.3 1 2 0 0.0001 17 0 0 0 1.15E+08 1.14E+08 - - - 9.1436 0.9901 221125_WJC_METTL3_EV_vs_WT_F03.19226.19226.2 0.549 18-Jul K.DRPFFPGLVK.Y "sp|O60361|NDK8_HUMAN,sp|P22392|NDKB_HUMAN,tr|Q32Q12|Q32Q12_HUMAN,tr|J3KPD9|J3KPD9_HUMAN,tr|F6XY72|F6XY72_HUMAN" 5 1174.6499 1.18 34262 19226 2 1174.648064 588.3322 Putative nucleoside diphosphate kinase OS=Homo sapiens OX=9606 GN=NME2P1 PE=5 SV=1 8.75 3224.9 - 4.85E+06 - - - -1.5451 - 1.587 0.126 - 153.2 5 2 0 -0.0018 10 0 0 0 1.36E+08 1.15E+08 - - - 0.948 0.9973 221125_WJC_METTL3_EV_vs_WT_F03.19227.19227.3 0.000812 Oct-56 K.ELLHSQNTWLNTELK.T sp|P12270|TPR_HUMAN 1 1824.937 16.22 34263 19227 3 1824.944854 609.3196 Nucleoprotein TPR OS=Homo sapiens OX=9606 GN=TPR PE=1 SV=3 5.4 3224.9 - 3.79E+06 - - - 4.2966 - 1.995 0.356 - 110.2 1 2 0 0.0078 15 0 0 0 1.07E+07 6.59E+05 - - - 4.309 1 221125_WJC_METTL3_EV_vs_WT_F03.19236.19236.3 9.26E-08 19/56 R.LLIHQSLAGGIIGVK.G "sp|P61978|HNRPK_HUMAN,tr|Q5T6W2|Q5T6W2_HUMAN" 2 1517.9293 1.18 34272 19236 3 1517.929522 506.9837 Heterogeneous nuclear ribonucleoprotein K OS=Homo sapiens OX=9606 GN=HNRNPK PE=1 SV=1 8.76 3225.7 - 1.11E+06 - - - 0.114 - 3.682 0.538 - 581.5 1 2 0 0.0002 15 0 0 0 3.77E+07 3.21E+07 - - - 7.9393 1 221125_WJC_METTL3_EV_vs_WT_F03.19238.19238.3 1.42E-07 18/56 R.LLIHQSLAGGIIGVK[136.11].G "sp|P61978|HNRPK_HUMAN,tr|Q5T6W2|Q5T6W2_HUMAN" 2 1525.9435 1.18 34274 19238 3 1525.942531 509.6551 Heterogeneous nuclear ribonucleoprotein K OS=Homo sapiens OX=9606 GN=HNRNPK PE=1 SV=1 8.76 3226 - 988133 - - - -0.6671 - 3.5 0.379 - 528.2 1 2 0 -0.001 15 0 0 0 3.80E+07 3.23E+07 - - - 6.0341 0.9834 221125_WJC_METTL3_EV_vs_WT_F03.19239.19239.3 0.0417 13/56 K.GILADEDSSRPVWLK.A "sp|P49327|FAS_HUMAN,tr|A0A0U1RQF0|A0A0U1RQF0_HUMAN" 2 1684.8784 0.65 34275 19239 3 1684.875228 562.6334 Fatty acid synthase OS=Homo sapiens OX=9606 GN=FASN PE=1 SV=3 4.56 3226 - 1.61E+06 - - - -1.9034 - 1.871 0.147 - 156.5 1 2 0 -0.0032 15 0 0 0 8.26E+06 1.27E+07 - - - 1.8127 0.9999 221125_WJC_METTL3_EV_vs_WT_F03.19240.19240.3 0.000816 Dec-44 R.TIHTDVLFGVVK[136.11].A "sp|Q9H6R0|DHX33_HUMAN,tr|I3L1L6|I3L1L6_HUMAN" 2 1335.7642 0.92 34276 19240 3 1335.763552 446.262 ATP-dependent RNA helicase DHX33 OS=Homo sapiens OX=9606 GN=DHX33 PE=1 SV=2 6.41 3226.1 - 668221 - - - -0.4754 - 1.876 0.432 - 136.6 1 2 0 -0.0006 12 0 0 0 2.52E+06 2.73E+06 - - - 5.1001 0.9986 221125_WJC_METTL3_EV_vs_WT_F03.19246.19246.2 0.0503 18-Aug K.DR[166.11]PFFPGLVK[136.11].Y "sp|O60361|NDK8_HUMAN,sp|P22392|NDKB_HUMAN,tr|Q32Q12|Q32Q12_HUMAN,tr|J3KPD9|J3KPD9_HUMAN,tr|F6XY72|F6XY72_HUMAN" 5 1192.6723 1.25 34281 19246 2 1192.670576 597.3435 Putative nucleoside diphosphate kinase OS=Homo sapiens OX=9606 GN=NME2P1 PE=5 SV=1 8.75 3226.8 - 1.03E+07 - - - -1.4866 - 1.697 0.263 - 219.4 1 2 0 -0.0018 10 0 0 0 1.36E+08 1.09E+08 - - - 2.4592 0.9999 221125_WJC_METTL3_EV_vs_WT_F03.19249.19249.3 3.60E-05 15/56 K.GILADEDSSR[166.11]PVWLK[136.11].A "sp|P49327|FAS_HUMAN,tr|A0A0U1RQF0|A0A0U1RQF0_HUMAN" 2 1702.9009 0.65 34284 19249 3 1702.899173 568.6409 Fatty acid synthase OS=Homo sapiens OX=9606 GN=FASN PE=1 SV=3 4.56 3226.9 - 2.68E+06 - - - -1.0171 - 3.004 0.352 - 194.8 1 2 0 -0.0017 15 0 0 0 8.26E+06 1.27E+07 - - - 5.3341 0.9997 221125_WJC_METTL3_EV_vs_WT_F03.19251.19251.3 1.34E-08 14/48 R.DEEVHAGLGELLR.S "sp|P50454|SERPH_HUMAN,tr|E9PNX1|E9PNX1_HUMAN,tr|E9PIG2|E9PIG2_HUMAN,tr|E9PPV6|E9PPV6_HUMAN,tr|E9PR70|E9PR70_HUMAN,tr|E9PMI5|E9PMI5_HUMAN,tr|E9PRS3|E9PRS3_HUMAN,tr|E9PJH8|E9PJH8_HUMAN,tr|E9PK86|E9PK86_HUMAN,tr|E9PQ34|E9PQ34_HUMAN" 10 1436.726 2.95 34286 19251 3 1436.721407 479.9159 Serpin H1 OS=Homo sapiens OX=9606 GN=SERPINH1 PE=1 SV=2 4.4 3227 - 2.43E+06 - - - -3.1669 - 2.631 0.405 - 351.3 1 2 0 -0.0046 13 0 0 0 1.58E+07 5.33E+06 - - - 5.6769 1 221125_WJC_METTL3_EV_vs_WT_F03.19254.19254.2 2.16E-10 15/32 R.FSGVPDRFSGSGSGTDF.T "sp|A2NJV5|KV229_HUMAN,sp|A0A075B6S2|KVD29_HUMAN,sp|A0A0A0MRZ7|KVD26_HUMAN" 3 1718.7536 999 34289 19254 2 1718.754987 860.3841 Immunoglobulin kappa variable 2-29 OS=Homo sapiens OX=9606 GN=IGKV2-29 PE=3 SV=2 4.21 3227.4 - 1.33E+06 - - - 0.7901 - 2.747 0.648 - 460.5 1 1 1 0.0014 17 0 0 0 8.09E+06 0.00E+00 - - - 6.3111 1 221125_WJC_METTL3_EV_vs_WT_F03.19257.19257.2 1.39E-11 18/34 K.YIDSADLEPITSQEEPVR[166.11].Y "sp|P17812|PYRG1_HUMAN,tr|A0A3B3ITF6|A0A3B3ITF6_HUMAN,tr|B4E1E0|B4E1E0_HUMAN,tr|A0A3B3IRQ8|A0A3B3IRQ8_HUMAN,tr|A0A3B3IRI2|A0A3B3IRI2_HUMAN" 5 2070.9985 0.74 34292 19257 2 2070.99634 1036.5065 CTP synthase 1 OS=Homo sapiens OX=9606 GN=CTPS1 PE=1 SV=2 3.83 3227.8 - 827518 - - - -1.043 - 3.53 0.697 - 566.5 1 2 0 -0.0022 18 0 0 0 3.28E+06 4.41E+06 - - - 7.2893 1 221125_WJC_METTL3_EV_vs_WT_F03.19260.19260.3 1.17E-06 18/52 K.NVALLSQLYHSPAR.R sp|Q15717|ELAV1_HUMAN 1 1567.8471 1.38 34294 19260 3 1567.846253 523.623 ELAV-like protein 1 OS=Homo sapiens OX=9606 GN=ELAVL1 PE=1 SV=2 8.75 3228.1 - 1.37E+07 - - - -0.5249 - 2.899 0.546 - 408 1 2 0 -0.0008 14 0 0 0 1.63E+08 1.18E+08 - - - 7.4557 1 221125_WJC_METTL3_EV_vs_WT_F03.19261.19261.3 3.28E-05 14/52 K.NVALLSQLYHSPAR[166.11].R sp|Q15717|ELAV1_HUMAN 1 1577.8553 1.38 34295 19261 3 1577.854002 526.9591 ELAV-like protein 1 OS=Homo sapiens OX=9606 GN=ELAVL1 PE=1 SV=2 8.75 3228.2 - 6.92E+06 - - - -0.8518 - 2.485 0.463 - 185.3 1 2 0 -0.0013 14 0 0 0 1.63E+08 1.18E+08 - - - 6.1207 1 221125_WJC_METTL3_EV_vs_WT_F03.19264.19264.3 1.22E-06 Dec-52 R.FQSGDFHVINGVLR[166.11].T sp|P55060|XPO2_HUMAN 1 1597.824 0.77 34298 19264 3 1597.821895 533.6153 Exportin-2 OS=Homo sapiens OX=9606 GN=CSE1L PE=1 SV=3 6.74 3228.3 - 3.08E+06 - - - -1.3456 - 2.285 0.603 - 111.9 1 2 0 -0.0022 14 0 0 0 1.91E+07 2.46E+07 - - - 7.4584 1 221125_WJC_METTL3_EV_vs_WT_F03.19266.19266.3 6.04E-10 16/60 K.IFTVGHQVPDDETIFK[136.11].F "sp|O75319|DUS11_HUMAN,tr|H7C0E6|H7C0E6_HUMAN" 2 1852.9451 1.45 34300 19266 3 1852.946066 618.6556 RNA\RNP complex-1-interacting phosphatase OS=Homo sapiens OX=9606 GN=DUSP11 PE=1 SV=2 4.54 3228.4 - 2.68E+06 - - - 0.5402 - 3.296 0.586 - 282.5 1 2 0 0.001 16 0 0 0 4.49E+07 3.11E+07 - - - 8.1334 0.9999 221125_WJC_METTL3_EV_vs_WT_F03.19268.19268.2 0.000586 13/26 K.NLSSNEAISLEEIR[166.11].L sp|P78527|PRKDC_HUMAN 1 1583.803 0.2 34302 19268 2 1583.801039 792.9088 DNA-dependent protein kinase catalytic subunit OS=Homo sapiens OX=9606 GN=PRKDC PE=1 SV=3 4.25 3228.7 - 1.26E+06 - - - -1.2603 - 2.977 0.49 - 483.1 1 2 0 -0.002 14 0 0 0 2.70E+06 1.32E+07 - - - 5.3971 0.9975 221125_WJC_METTL3_EV_vs_WT_F03.19269.19269.3 0.162 Nov-40 R.LQLPVWEYK[136.11]DR[166.11].F sp|O43143|DHX15_HUMAN 1 1463.7892 5.92 34303 19269 3 1463.789104 488.937 Pre-mRNA-splicing factor ATP-dependent RNA helicase DHX15 OS=Homo sapiens OX=9606 GN=DHX15 PE=1 SV=2 6.07 3228.8 - 1.25E+06 - - - -0.0451 - 1.935 0.299 - 123.4 1 2 1 -0.0001 11 0 0 0 5.84E+07 9.87E+06 - - - 3.7488 0.9986 221125_WJC_METTL3_EV_vs_WT_F03.19271.19271.2 0.000889 22-Sep R.LSIPTYGLQC[160.03]TR[166.11].A "sp|P49327|FAS_HUMAN,tr|A0A0U1RQF0|A0A0U1RQF0_HUMAN,tr|J3KTF0|J3KTF0_HUMAN" 3 1417.7263 0.4 34305 19271 2 1417.721951 709.8704 Fatty acid synthase OS=Homo sapiens OX=9606 GN=FASN PE=1 SV=3 8.22 3229 - 1.07E+06 - - - -3.0711 - 2.003 0.367 - 264.1 1 2 0 -0.0044 12 0 0 0 1.36E+07 3.41E+07 - - - 3.578 0.9999 221125_WJC_METTL3_EV_vs_WT_F03.19272.19272.2 0.000287 18-Dec K.FAEAFEAIPR[166.11].A sp|P50990|TCPQ_HUMAN 1 1159.5901 0.39 34306 19272 2 1159.590723 580.8023 T-complex protein 1 subunit theta OS=Homo sapiens OX=9606 GN=CCT8 PE=1 SV=4 4.53 3229.2 - 814342 - - - 0.5122 - 2.383 0.533 - 494.9 1 2 0 0.0006 10 0 0 0 2.44E+06 6.31E+06 - - - 5.4014 1 221125_WJC_METTL3_EV_vs_WT_F03.19273.19273.2 8.73E-13 17/34 K.YIDSADLEPITSQEEPVR.Y "sp|P17812|PYRG1_HUMAN,tr|A0A3B3ITF6|A0A3B3ITF6_HUMAN,tr|B4E1E0|B4E1E0_HUMAN,tr|A0A3B3IRQ8|A0A3B3IRQ8_HUMAN,tr|A0A3B3IRI2|A0A3B3IRI2_HUMAN" 5 2060.9902 0.7 34307 19273 2 2060.991214 1031.5024 CTP synthase 1 OS=Homo sapiens OX=9606 GN=CTPS1 PE=1 SV=2 3.83 3229.3 - 647627 - - - 0.4774 - 3.499 0.71 - 414.2 1 2 0 0.001 18 0 0 0 3.07E+06 4.41E+06 - - - 7.364 1 221125_WJC_METTL3_EV_vs_WT_F03.19274.19274.2 2.32E-10 14/34 K.EMFPYEASTPTGISASC[160.03]R[166.11].R "sp|P42167|LAP2B_HUMAN,tr|G5E972|G5E972_HUMAN,tr|H0YJH7|H0YJH7_HUMAN" 3 2012.8847 1.25 34308 19274 2 2012.879579 1007.4496 "Lamina-associated polypeptide 2, isoforms beta\gamma OS=Homo sapiens OX=9606 GN=TMPO PE=1 SV=2" 4.53 3229.4 - 589944 - - - -2.5605 - 2.425 0.712 - 363.8 1 2 0 -0.0052 18 0 0 0 5.62E+06 4.51E+06 - - - 6.4761 0.9998 221125_WJC_METTL3_EV_vs_WT_F03.19275.19275.3 0.000262 Dec-48 R.ELSPDIAHLASLK[136.11].T sp|Q8N1G4|LRC47_HUMAN 1 1400.7755 1 34309 19275 3 1400.772225 467.9324 Leucine-rich repeat-containing protein 47 OS=Homo sapiens OX=9606 GN=LRRC47 PE=1 SV=1 5.32 3229.5 - 509766 - - - -2.3237 - 2.575 0.363 - 145.6 1 2 0 -0.0033 13 0 0 0 2.38E+07 2.38E+07 - - - 5.1507 0.9847 221125_WJC_METTL3_EV_vs_WT_F03.19278.19278.2 6.58E-07 26-Nov K.R[166.11]PLDDGVGNQLGAL.V sp|Q96I24|FUBP3_HUMAN 1 1433.7502 1.94 34311 19278 2 1433.74871 717.8824 Far upstream element-binding protein 3 OS=Homo sapiens OX=9606 GN=FUBP3 PE=1 SV=2 4.21 3229.9 - 1.20E+06 - - - -1.0476 - 2.581 0.35 - 363.6 1 1 0 -0.0015 14 0 0 0 4.06E+07 2.09E+07 - - - 4.005 0.9851 221125_WJC_METTL3_EV_vs_WT_F03.19280.19280.2 5.30E-05 13/26 K.NLSSNEAISLEEIR.L sp|P78527|PRKDC_HUMAN 1 1573.7948 -1 34312 19280 2 1573.809498 787.9047 DNA-dependent protein kinase catalytic subunit OS=Homo sapiens OX=9606 GN=PRKDC PE=1 SV=3 4.25 3230.1 - 3.04E+06 - - - 9.3614 - 2.545 0.481 - 574.1 1 2 0 0.0147 14 0 0 0 0.00E+00 0.00E+00 - - - 4.9332 0.9997 221125_WJC_METTL3_EV_vs_WT_F03.19283.19283.3 0.000208 Oct-60 R.FVKEPAFEDITLESER.K "sp|O75400|PR40A_HUMAN,tr|A0A7N4I394|A0A7N4I394_HUMAN" 2 1908.9469 3.34 34315 19283 3 1908.945206 637.3229 Pre-mRNA-processing factor 40 homolog A OS=Homo sapiens OX=9606 GN=PRPF40A PE=1 SV=2 4.25 3230.3 - 2.68E+06 - - - -0.8921 - 2.13 0.471 - 96.6 1 2 1 -0.0017 16 0 0 0 5.42E+07 1.62E+07 - - - 5.7308 0.9999 221125_WJC_METTL3_EV_vs_WT_F03.19284.19284.3 0.00104 13/56 K.LIQSEVALNDLHLTK[136.11].Q "sp|Q15643|TRIPB_HUMAN,tr|H0YJ97|H0YJ97_HUMAN" 2 1700.9552 1.19 34316 19284 3 1700.95616 567.9924 Thyroid receptor-interacting protein 11 OS=Homo sapiens OX=9606 GN=TRIP11 PE=1 SV=3 5.32 3230.3 - 2.34E+06 - - - 0.5432 - 2.63 0.424 - 184.9 1 2 0 0.0009 15 0 0 0 2.29E+08 1.93E+08 - - - 5.7901 0.9999 221125_WJC_METTL3_EV_vs_WT_F03.19285.19285.3 5.32E-08 Dec-52 R.FQSGDFHVINGVLR.T sp|P55060|XPO2_HUMAN 1 1587.8158 0.78 34317 19285 3 1587.810851 530.2792 Exportin-2 OS=Homo sapiens OX=9606 GN=CSE1L PE=1 SV=3 6.74 3230.4 - 2.22E+06 - - - -3.1011 - 2.344 0.601 - 111.9 1 2 0 -0.0049 14 0 0 0 1.94E+07 2.49E+07 - - - 7.503 0.9998 221125_WJC_METTL3_EV_vs_WT_F03.19286.19286.3 0.000131 Dec-60 R.FVK[136.11]EPAFEDITLESER[166.11].K "sp|O75400|PR40A_HUMAN,tr|A0A7N4I394|A0A7N4I394_HUMAN" 2 1926.9694 2.46 34318 19286 3 1926.968285 643.3304 Pre-mRNA-processing factor 40 homolog A OS=Homo sapiens OX=9606 GN=PRPF40A PE=1 SV=2 4.25 3230.4 - 2.20E+06 - - - -0.5677 - 2.75 0.469 - 141 1 2 1 -0.0011 16 0 0 0 4.04E+07 1.64E+07 - - - 6.3642 0.9954 221125_WJC_METTL3_EV_vs_WT_F03.19287.19287.3 0.0418 Jul-36 R.GYFEYIEENK[136.11].Y "sp|Q00839|HNRPU_HUMAN,tr|Q5RI18|Q5RI18_HUMAN,tr|A0A1W2PP35|A0A1W2PP35_HUMAN,tr|A0A1W2PPS1|A0A1W2PPS1_HUMAN,tr|A0A1W2PRI6|A0A1W2PRI6_HUMAN" 5 1298.591 1.06 34319 19287 3 1298.590151 433.871 Heterogeneous nuclear ribonucleoprotein U OS=Homo sapiens OX=9606 GN=HNRNPU PE=1 SV=6 4.25 3230.5 - 1.15E+06 - - - -0.6792 - 1.412 0.246 - 61.3 1 2 0 -0.0009 10 0 0 0 2.16E+07 2.03E+07 - - - 2.29 1 221125_WJC_METTL3_EV_vs_WT_F03.19290.19290.3 1.29E-06 14/68 K.EMFPYEASTPTGISASC[160.03]R.R "sp|P42167|LAP2B_HUMAN,tr|G5E972|G5E972_HUMAN,tr|H0YJH7|H0YJH7_HUMAN" 3 2002.8765 2.06 34322 19290 3 2002.875032 668.6328 "Lamina-associated polypeptide 2, isoforms beta\gamma OS=Homo sapiens OX=9606 GN=TMPO PE=1 SV=2" 4.53 3230.9 - 762113 - - - -0.7145 - 2.554 0.522 - 197.2 1 2 0 -0.0014 18 0 0 0 6.90E+06 3.35E+06 - - - 6.6943 1 221125_WJC_METTL3_EV_vs_WT_F03.19291.19291.3 4.84E-06 13/40 K.TFQAFELK[136.11]PLR[166.11].Q "sp|O60293|ZC3H1_HUMAN,tr|G3V1X1|G3V1X1_HUMAN" 2 1366.7728 0.98 34323 19291 3 1366.771342 456.5982 Zinc finger C3H1 domain-containing protein OS=Homo sapiens OX=9606 GN=ZFC3H1 PE=1 SV=3 8.41 3231 - 739728 - - - -1.0609 - 2.216 0.544 - 228.8 1 2 0 -0.0014 11 0 0 0 5.62E+06 5.72E+06 - - - 6.8651 0.9996 221125_WJC_METTL3_EV_vs_WT_F03.19292.19292.2 6.45E-07 22-Nov R.LSIPTYGLQC[160.03]TR.A "sp|P49327|FAS_HUMAN,tr|A0A0U1RQF0|A0A0U1RQF0_HUMAN,tr|J3KTF0|J3KTF0_HUMAN" 3 1407.718 0.44 34324 19292 2 1407.716835 704.8663 Fatty acid synthase OS=Homo sapiens OX=9606 GN=FASN PE=1 SV=3 8.22 3231.2 - 689408 - - - -0.8524 - 2.096 0.345 - 421.4 1 2 0 -0.0012 12 0 0 0 1.36E+07 3.13E+07 - - - 3.5359 1 221125_WJC_METTL3_EV_vs_WT_F03.19294.19294.3 7.67E-06 Nov-52 R.VYALPEDLVEVK[136.11]PK[136.11].M "sp|P13797|PLST_HUMAN,tr|A0A0A0MSQ0|A0A0A0MSQ0_HUMAN" 2 1614.9204 0.57 34326 19294 3 1614.921038 539.3141 Plastin-3 OS=Homo sapiens OX=9606 GN=PLS3 PE=1 SV=4 4.68 3231.4 - 657215 - - - 0.4198 - 2.395 0.461 - 115.5 1 2 0 0.0007 14 0 0 0 9.70E+06 1.69E+07 - - - 6.0006 1 221125_WJC_METTL3_EV_vs_WT_F03.19295.19295.2 2.53E-09 Dec-32 G.SSGGYGGLGGFGGGSFR.G "sp|P13645|K1C10_HUMAN,tr|A0A1B0GVI3|A0A1B0GVI3_HUMAN" 2 1518.6852 999 34327 19295 2 1518.679165 760.3499 "Keratin, type I cytoskeletal 10 OS=Homo sapiens OX=9606 GN=KRT10 PE=1 SV=6" 8.46 3231.6 - 557212 - - - -3.9442 - 2.504 0.644 - 271.9 1 1 0 -0.006 17 0 0 0 2.24E+06 0.00E+00 - - - 6.0524 0.9996 221125_WJC_METTL3_EV_vs_WT_F03.19296.19296.3 8.55E-05 Dec-56 K.VLDPEK[136.11]QADMLDSLR[166.11].L "sp|Q9Y4A5|TRRAP_HUMAN,tr|H0Y4W2|H0Y4W2_HUMAN,tr|F2Z2U4|F2Z2U4_HUMAN" 3 1746.8941 0.75 34328 19296 3 1746.894662 583.3053 Transformation\transcription domain-associated protein OS=Homo sapiens OX=9606 GN=TRRAP PE=1 SV=3 4.23 3231.7 - 538801 - - - 0.3189 - 2.678 0.379 - 196.6 1 2 1 0.0006 15 0 0 0 2.95E+06 3.91E+06 - - - 5.3357 0.9991 221125_WJC_METTL3_EV_vs_WT_F03.19301.19301.2 3.59E-05 20-Nov R.ITWLYDNTTGK.Q "sp|Q08188|TGM3_HUMAN,tr|A0A494C0J7|A0A494C0J7_HUMAN" 2 1310.6507 62.7 34331 19301 2 1310.654781 656.3326 Protein-glutamine gamma-glutamyltransferase E OS=Homo sapiens OX=9606 GN=TGM3 PE=1 SV=4 5.83 3232.4 - 3.78E+06 - - - 3.1389 - 2.032 0.437 - 373.5 1 2 0 0.0041 11 0 0 0 4.85E+07 7.74E+05 - - - 4.1855 1 221125_WJC_METTL3_EV_vs_WT_F03.19302.19302.3 8.93E-08 13/60 K.IFTVGHQVPDDETIFK.F "sp|O75319|DUS11_HUMAN,tr|H7C0E6|H7C0E6_HUMAN" 2 1844.9309 1.43 34332 19302 3 1844.931752 615.9842 RNA\RNP complex-1-interacting phosphatase OS=Homo sapiens OX=9606 GN=DUSP11 PE=1 SV=2 4.54 3232.4 - 3.99E+06 - - - 0.4808 - 2.437 0.557 - 184.5 1 2 0 0.0009 16 0 0 0 4.49E+07 3.15E+07 - - - 7.0353 1 221125_WJC_METTL3_EV_vs_WT_F03.19304.19304.3 4.96E-06 13/48 R.SVFALTNGIYPHK[136.11].L sp|Q02878|RL6_HUMAN 1 1453.7809 1.06 34334 19304 3 1453.780267 485.6009 60S ribosomal protein L6 OS=Homo sapiens OX=9606 GN=RPL6 PE=1 SV=3 8.33 3232.5 - 2.66E+06 - - - -0.4354 - 2.327 0.49 - 150.7 1 2 0 -0.0006 13 0 0 0 5.46E+07 5.12E+07 - - - 6.2927 1 221125_WJC_METTL3_EV_vs_WT_F03.19305.19305.3 0.0627 15/48 K.VTLVFEHVDQDLR[166.11].T "sp|P11802|CDK4_HUMAN,tr|F8VWX7|F8VWX7_HUMAN,tr|F8W1L8|F8W1L8_HUMAN,tr|F8VXD2|F8VXD2_HUMAN,tr|F8VZZ0|F8VZZ0_HUMAN,tr|F8VTV8|F8VTV8_HUMAN,tr|F8VYH9|F8VYH9_HUMAN,tr|F8VZ51|F8VZ51_HUMAN" 8 1579.8234 0.47 34335 19305 3 1579.821645 527.6151 Cyclin-dependent kinase 4 OS=Homo sapiens OX=9606 GN=CDK4 PE=1 SV=2 4.54 3232.6 - 2.60E+06 - - - -1.0963 - 2.705 0.478 - 332.1 1 2 0 -0.0017 13 0 0 0 9.32E+06 1.97E+07 - - - 6.5668 0.9997 221125_WJC_METTL3_EV_vs_WT_F03.19306.19306.3 0.00319 Dec-48 R.SVFALTNGIYPHK.L sp|Q02878|RL6_HUMAN 1 1445.7667 1.03 34336 19306 3 1445.767399 482.9295 60S ribosomal protein L6 OS=Homo sapiens OX=9606 GN=RPL6 PE=1 SV=3 8.33 3232.6 - 2.51E+06 - - - 0.4835 - 2.146 0.335 - 136.5 1 2 0 0.0007 13 0 0 0 5.24E+07 5.11E+07 - - - 4.3451 1 221125_WJC_METTL3_EV_vs_WT_F03.19308.19308.2 3.84E-06 16/26 K.SLYDEVAAQGEVVR.K "sp|P07814|SYEP_HUMAN,tr|V9GYZ6|V9GYZ6_HUMAN" 2 1534.7627 1.07 34338 19308 2 1534.770384 768.3886 Bifunctional glutamate\proline--tRNA ligase OS=Homo sapiens OX=9606 GN=EPRS1 PE=1 SV=5 4.14 3232.7 - 1.96E+06 - - - 4.9825 - 2.8 0.598 - 805.2 1 2 0 0.0076 14 0 0 0 1.92E+07 1.79E+07 - - - 6.0392 1 221125_WJC_METTL3_EV_vs_WT_F03.19313.19313.3 0.000378 16/48 R.ELSPDIAHLASLK.T sp|Q8N1G4|LRC47_HUMAN 1 1392.7613 1 34343 19313 3 1392.7613 465.261 Leucine-rich repeat-containing protein 47 OS=Homo sapiens OX=9606 GN=LRRC47 PE=1 SV=1 5.32 3233.2 - 744426 - - - 0.0144 - 3.081 0.451 - 500 1 2 0 0 13 0 0 0 2.38E+07 2.38E+07 - - - 6.6191 1 221125_WJC_METTL3_EV_vs_WT_F03.19314.19314.2 2.62E-09 14/28 K.FTQSALDC[160.03]MSVEVGR[166.11].L "sp|Q14203|DCTN1_HUMAN,tr|A0A804CDA6|A0A804CDA6_HUMAN,tr|E7EX90|E7EX90_HUMAN,tr|A0A7P0Z4C3|A0A7P0Z4C3_HUMAN,tr|Q6AWB1|Q6AWB1_HUMAN" 5 1708.7788 2.55 34344 19314 2 1708.777151 855.3967 Dynactin subunit 1 OS=Homo sapiens OX=9606 GN=DCTN1 PE=1 SV=3 4.37 3233.3 - 702384 - - - -0.9715 - 3.021 0.665 - 684.5 1 2 0 -0.0017 15 0 0 0 2.27E+07 8.89E+06 - - - 6.6703 0.9999 221125_WJC_METTL3_EV_vs_WT_F03.19315.19315.3 0.0806 Dec-40 K.TFQAFELKPLR.Q "sp|O60293|ZC3H1_HUMAN,tr|G3V1X1|G3V1X1_HUMAN" 2 1348.7503 0.94 34345 19315 3 1348.74945 450.5907 Zinc finger C3H1 domain-containing protein OS=Homo sapiens OX=9606 GN=ZFC3H1 PE=1 SV=3 8.41 3233.5 - 622322 - - - -0.6465 - 1.976 0.399 - 183.3 1 2 0 -0.0009 11 0 0 0 5.68E+06 6.06E+06 - - - 4.923 1 221125_WJC_METTL3_EV_vs_WT_F03.19317.19317.2 1.69E-11 16/34 K.EMFPYEASTPTGISASC[160.03]R.R "sp|P42167|LAP2B_HUMAN,tr|G5E972|G5E972_HUMAN,tr|H0YJH7|H0YJH7_HUMAN" 3 2002.8765 1.25 34347 19317 2 2002.877399 1002.4455 "Lamina-associated polypeptide 2, isoforms beta\gamma OS=Homo sapiens OX=9606 GN=TMPO PE=1 SV=2" 4.53 3233.7 - 424043 - - - 0.4673 - 2.8 0.654 - 645.8 1 2 0 0.0009 18 0 0 0 5.62E+06 4.51E+06 - - - 6.4025 0.9992 221125_WJC_METTL3_EV_vs_WT_F03.19318.19318.2 0.00303 24-Nov K.GSTLDLSDLEAEK[136.11].L sp|O00767|SCD_HUMAN 1 1384.6813 1.47 34348 19318 2 1384.678162 693.3479 Stearoyl-CoA desaturase OS=Homo sapiens OX=9606 GN=SCD PE=1 SV=2 3.92 3233.9 - 403677 - - - -2.2698 - 2.092 0.348 - 299 1 2 0 -0.0031 13 0 0 0 1.92E+07 1.31E+07 - - - 3.5047 0.9999 221125_WJC_METTL3_EV_vs_WT_F03.19320.19320.3 5.69E-05 Oct-36 R.RAPFDLFENK.K "sp|P08238|HS90B_HUMAN,sp|Q58FF7|H90B3_HUMAN" 2 1235.6299 1.05 34350 19320 3 1235.62852 412.8839 Heat shock protein HSP 90-beta OS=Homo sapiens OX=9606 GN=HSP90AB1 PE=1 SV=4 6.07 3234.1 - 185811 - - - -1.0942 - 1.935 0.45 - 152.7 1 2 0 -0.0014 10 0 0 0 4.77E+06 4.54E+06 - - - 5.4845 1 221125_WJC_METTL3_EV_vs_WT_F03.19325.19325.3 7.52E-10 18/76 K.VNNASLIGLGYTQTLR[166.11]PGVK[136.11].L sp|Q9Y277|VDAC3_HUMAN 1 2118.1916 1.37 34353 19325 3 2118.192237 707.0711 Voltage-dependent anion-selective channel protein 3 OS=Homo sapiens OX=9606 GN=VDAC3 PE=1 SV=1 9.99 3234.7 - 1.69E+06 - - - 0.297 - 3.754 0.594 - 402.1 1 2 0 0.0006 20 0 0 0 1.26E+07 9.16E+06 - - - 8.3715 1 221125_WJC_METTL3_EV_vs_WT_F03.19326.19326.2 1.73E-12 15/28 K.FTQSALDC[160.03]MSVEVGR.L "sp|Q14203|DCTN1_HUMAN,tr|A0A804CDA6|A0A804CDA6_HUMAN,tr|E7EX90|E7EX90_HUMAN,tr|A0A7P0Z4C3|A0A7P0Z4C3_HUMAN,tr|Q6AWB1|Q6AWB1_HUMAN" 5 1698.7705 2.63 34354 19326 2 1698.770533 850.3925 Dynactin subunit 1 OS=Homo sapiens OX=9606 GN=DCTN1 PE=1 SV=3 4.37 3234.8 - 1.66E+06 - - - -0.0047 - 3.433 0.663 - 855.3 1 2 0 0 15 0 0 0 2.33E+07 8.89E+06 - - - 6.9704 0.998 221125_WJC_METTL3_EV_vs_WT_F03.19327.19327.2 7.95E-07 14/22 R.TATGAISAVFGR[166.11].S "sp|Q9Y4A5|TRRAP_HUMAN,tr|H0Y4W2|H0Y4W2_HUMAN,tr|F2Z2U4|F2Z2U4_HUMAN" 3 1159.6225 1.21 34355 19327 2 1159.628327 580.8185 Transformation\transcription domain-associated protein OS=Homo sapiens OX=9606 GN=TRRAP PE=1 SV=3 9.41 3234.9 - 1.26E+06 - - - 5.0318 - 2.681 0.488 - 822 1 2 0 0.0058 12 0 0 0 1.62E+07 1.35E+07 - - - 5.2384 0.9999 221125_WJC_METTL3_EV_vs_WT_F03.19328.19328.2 9.22E-05 14/24 R.EQEELEEALEVER.Q "sp|P51948|MAT1_HUMAN,tr|H0YJF2|H0YJF2_HUMAN,tr|H0YJ92|H0YJ92_HUMAN" 3 1601.7421 1.41 34356 19328 2 1601.743154 801.8783 CDK-activating kinase assembly factor MAT1 OS=Homo sapiens OX=9606 GN=MNAT1 PE=1 SV=1 3.83 3235 - 1.22E+06 - - - 0.6824 - 2.531 0.498 - 766.5 1 2 0 0.0011 13 0 0 0 1.77E+07 1.25E+07 - - - 5.1022 0.9998 221125_WJC_METTL3_EV_vs_WT_F03.19333.19333.2 3.36E-05 13/34 K.VGINYQPPTVVPGGDLAK[136.11].V "sp|Q9NY65|TBA8_HUMAN,sp|Q6PEY2|TBA3E_HUMAN,sp|P0DPH7|TBA3C_HUMAN,sp|Q71U36|TBA1A_HUMAN,sp|P0DPH8|TBA3D_HUMAN,sp|P68366|TBA4A_HUMAN,sp|P68363|TBA1B_HUMAN,sp|Q9BQE3|TBA1C_HUMAN,tr|A0A1W2PQM2|A0A1W2PQM2_HUMAN,tr|F5H5D3|F5H5D3_HUMAN,tr|C9J2C0|C9J2C0_HUMAN,tr|V9GZ17|V9GZ17_HUMAN,tr|A0A7P0T945|A0A7P0T945_HUMAN" 13 1831.9923 0.6 34361 19333 2 1831.993757 917.0035 Tubulin alpha-8 chain OS=Homo sapiens OX=9606 GN=TUBA8 PE=1 SV=1 5.81 3235.6 - 683544 - - - 0.7686 - 1.965 0.466 - 246 1 2 0 0.0014 18 0 0 0 4.97E+06 8.29E+06 - - - 4.1432 0.9998 221125_WJC_METTL3_EV_vs_WT_F03.19336.19336.3 0.000909 Sep-40 K.ISMPDVDLHLK.G "sp|Q09666|AHNK_HUMAN,sp|Q09666|AHNK_HUMAN,sp|Q09666|AHNK_HUMAN,sp|Q09666|AHNK_HUMAN,sp|Q09666|AHNK_HUMAN" 5 1266.6642 0.99 34364 19336 3 1266.663753 423.2287 Neuroblast differentiation-associated protein AHNAK OS=Homo sapiens OX=9606 GN=AHNAK PE=1 SV=2 5.21 3236 - 477117 - - - -0.36 - 1.771 0.41 - 103.3 1 2 0 -0.0005 11 0 0 0 2.89E+06 2.92E+06 - - - 4.7346 0.9999 221125_WJC_METTL3_EV_vs_WT_F03.19337.19337.3 0.00701 14/36 R.SHAVFQIILR.R "sp|O00139|KIF2A_HUMAN,tr|D6R9M0|D6R9M0_HUMAN,tr|A0A6Q8PFA6|A0A6Q8PFA6_HUMAN,tr|A0A6Q8PGH7|A0A6Q8PGH7_HUMAN,tr|A0A6Q8PG37|A0A6Q8PG37_HUMAN,tr|A0A6Q8PH57|A0A6Q8PH57_HUMAN" 6 1182.6873 5.3 34365 19337 3 1182.686088 395.2364 Kinesin-like protein KIF2A OS=Homo sapiens OX=9606 GN=KIF2A PE=1 SV=3 9.49 3236.1 - 418151 - - - -1.0476 - 2.129 0.433 - 360.1 1 2 0 -0.0012 10 0 0 0 9.14E+06 1.73E+06 - - - 5.574 0.9975 221125_WJC_METTL3_EV_vs_WT_F03.19338.19338.2 8.19E-05 26-Aug R.SMVTEEFNGSDWEK.A sp|Q7Z7K6|CENPV_HUMAN 1 1657.693 0.92 34366 19338 2 1657.700892 829.8538 Centromere protein V OS=Homo sapiens OX=9606 GN=CENPV PE=1 SV=1 4 3236.3 - 281079 - - - 4.7596 - 1.774 0.548 - 52.9 1 2 0 0.0079 14 0 0 0 2.70E+06 2.95E+06 - - - 4.5246 0.9993 221125_WJC_METTL3_EV_vs_WT_F03.19339.19339.3 0.000776 Sep-40 K.DLFDYSPPLHK[136.11].N "sp|Q9NYF8|BCLF1_HUMAN,tr|E9PKI6|E9PKI6_HUMAN,tr|A0A1W2PQ43|A0A1W2PQ43_HUMAN,tr|E9PK91|E9PK91_HUMAN,tr|E9PK09|E9PK09_HUMAN,tr|E9PQN2|E9PQN2_HUMAN" 6 1338.67 2.17 34367 19339 3 1338.673992 447.2306 Bcl-2-associated transcription factor 1 OS=Homo sapiens OX=9606 GN=BCLAF1 PE=1 SV=2 5.21 3236.4 - 265526 - - - 3.0179 - 1.575 0.43 - 101.8 1 2 0 0.004 11 0 0 0 1.03E+07 4.74E+06 - - - 4.6234 0.9997 221125_WJC_METTL3_EV_vs_WT_F03.19340.19340.3 0.00357 Oct-40 K.ISMPDVDLHLK[136.11].G "sp|Q09666|AHNK_HUMAN,sp|Q09666|AHNK_HUMAN,sp|Q09666|AHNK_HUMAN,sp|Q09666|AHNK_HUMAN,sp|Q09666|AHNK_HUMAN" 5 1274.6784 0.99 34368 19340 3 1274.678294 425.9001 Neuroblast differentiation-associated protein AHNAK OS=Homo sapiens OX=9606 GN=AHNAK PE=1 SV=2 5.21 3236.5 - 249947 - - - -0.0902 - 2.02 0.34 - 154.8 1 2 0 -0.0001 11 0 0 0 2.89E+06 2.92E+06 - - - 4.328 1 221125_WJC_METTL3_EV_vs_WT_F03.19344.19344.2 1.91E-10 15/26 K.SLYDEVAAQGEVVR[166.11].K "sp|P07814|SYEP_HUMAN,tr|V9GYZ6|V9GYZ6_HUMAN" 2 1544.771 1.07 34370 19344 2 1544.771119 773.3928 Bifunctional glutamate\proline--tRNA ligase OS=Homo sapiens OX=9606 GN=EPRS1 PE=1 SV=5 4.14 3237 - 1.83E+06 - - - 0.0725 - 2.714 0.677 - 706.5 1 2 0 0.0001 14 0 0 0 1.92E+07 1.79E+07 - - - 6.5468 0.9999 221125_WJC_METTL3_EV_vs_WT_F03.19345.19345.2 0.00165 20-Nov R.AFSDPFVEAEK[136.11].S "sp|P34932|HSP74_HUMAN,tr|A0A087WTS8|A0A087WTS8_HUMAN,tr|A0A087WYC1|A0A087WYC1_HUMAN" 3 1246.5961 0.43 34371 19345 2 1246.595803 624.3053 Heat shock 70 kDa protein 4 OS=Homo sapiens OX=9606 GN=HSPA4 PE=1 SV=4 4.14 3237.1 - 1.81E+06 - - - -0.2535 - 2.101 0.52 - 302.5 1 2 0 -0.0003 11 0 0 0 1.55E+07 3.58E+07 - - - 4.89 0.9998 221125_WJC_METTL3_EV_vs_WT_F03.19348.19348.2 0.00605 24-Nov R.NFSMSVNSAAVLR.L "sp|Q6Y7W6|GGYF2_HUMAN,tr|C9JRZ2|C9JRZ2_HUMAN,tr|C9J0V6|C9J0V6_HUMAN,tr|I1E4Y6|I1E4Y6_HUMAN,tr|C9JHT0|C9JHT0_HUMAN,tr|C9JHW1|C9JHW1_HUMAN,tr|E7ESB6|E7ESB6_HUMAN" 7 1394.6976 3.42 34374 19348 2 1394.695939 698.3561 GRB10-interacting GYF protein 2 OS=Homo sapiens OX=9606 GN=GIGYF2 PE=1 SV=1 9.75 3237.2 - 1.83E+06 - - - -1.2153 - 2.494 0.422 - 407.6 1 2 0 -0.0017 13 0 0 0 1.90E+07 5.57E+06 - - - 4.5029 1 221125_WJC_METTL3_EV_vs_WT_F03.19350.19350.2 8.31E-07 15/26 R.QASPNIVIALSGNK.A sp|P20339|RAB5A_HUMAN 1 1410.7831 2.36 34376 19350 2 1410.784258 706.3988 Ras-related protein Rab-5A OS=Homo sapiens OX=9606 GN=RAB5A PE=1 SV=2 8.75 3237.4 - 1.75E+06 - - - 0.8364 - 3.126 0.547 - 1014 1 2 0 0.0012 14 0 0 0 2.60E+07 1.11E+07 - - - 5.9409 0.9999 221125_WJC_METTL3_EV_vs_WT_F03.19351.19351.3 4.01E-05 Sep-52 K.SPASDTYIVFGEAK[136.11].L "sp|E9PAV3|NACAM_HUMAN,sp|Q13765|NACA_HUMAN,tr|A0A7I2V473|A0A7I2V473_HUMAN,tr|F8VZJ2|F8VZJ2_HUMAN,tr|F8VNW4|F8VNW4_HUMAN,tr|A0A7I2V2K5|A0A7I2V2K5_HUMAN,tr|F8W0W4|F8W0W4_HUMAN,tr|H0YHX9|H0YHX9_HUMAN" 8 1491.7337 0.57 34377 19351 3 1491.73429 498.2518 "Nascent polypeptide-associated complex subunit alpha, muscle-specific form OS=Homo sapiens OX=9606 GN=NACA PE=1 SV=1" 4.37 3237.5 - 1.21E+06 - - - 0.4123 - 1.959 0.468 - 88.2 1 2 0 0.0006 14 0 0 0 2.87E+07 5.08E+07 - - - 5.5446 1 221125_WJC_METTL3_EV_vs_WT_F03.19352.19352.3 3.21E-09 20/76 K.VNNASLIGLGYTQTLRPGVK.L sp|Q9Y277|VDAC3_HUMAN 1 2100.1691 1.37 34378 19352 3 2100.169647 701.0637 Voltage-dependent anion-selective channel protein 3 OS=Homo sapiens OX=9606 GN=VDAC3 PE=1 SV=1 9.99 3237.6 - 1.15E+06 - - - 0.2424 - 4.188 0.61 - 554.5 1 2 0 0.0005 20 0 0 0 1.26E+07 9.16E+06 - - - 8.8154 0.9999 221125_WJC_METTL3_EV_vs_WT_F03.19354.19354.3 1.22E-05 13/48 K.VTLVFEHVDQDLR.T "sp|P11802|CDK4_HUMAN,tr|F8VWX7|F8VWX7_HUMAN,tr|F8W1L8|F8W1L8_HUMAN,tr|F8VXD2|F8VXD2_HUMAN,tr|F8VZZ0|F8VZZ0_HUMAN,tr|F8VTV8|F8VTV8_HUMAN,tr|F8VYH9|F8VYH9_HUMAN,tr|F8VZ51|F8VZ51_HUMAN" 8 1569.8151 0.45 34380 19354 3 1569.815334 524.279 Cyclin-dependent kinase 4 OS=Homo sapiens OX=9606 GN=CDK4 PE=1 SV=2 4.54 3237.9 - 784422 - - - 0.1446 - 2.4 0.425 - 248.2 1 2 0 0.0002 13 0 0 0 1.02E+07 2.27E+07 - - - 5.6519 1 221125_WJC_METTL3_EV_vs_WT_F03.19355.19355.3 1.75E-05 Dec-40 R.HFEELETIMDR.E "sp|Q8TAQ2|SMRC2_HUMAN,sp|Q92922|SMRC1_HUMAN,tr|F8VXC8|F8VXC8_HUMAN" 3 1418.65 6.3 34381 19355 3 1418.649094 473.8906 SWI\SNF complex subunit SMARCC2 OS=Homo sapiens OX=9606 GN=SMARCC2 PE=1 SV=1 4.4 3238 - 771533 - - - -0.6492 - 2.306 0.475 - 369.1 1 2 0 -0.0009 11 0 0 0 1.97E+07 3.12E+06 - - - 6.2091 0.9888 221125_WJC_METTL3_EV_vs_WT_F03.19357.19357.3 0.0265 13/48 K.LLSAEFLEQHYDR[166.11].F sp|Q9Y376|CAB39_HUMAN 1 1629.8026 1.69 34383 19357 3 1629.797046 544.2748 Calcium-binding protein 39 OS=Homo sapiens OX=9606 GN=CAB39 PE=1 SV=1 4.65 3238.3 - 504729 - - - -3.4329 - 1.779 0.239 - 220.8 1 2 0 -0.0056 13 0 0 0 5.61E+06 3.31E+06 - - - 2.7649 1 221125_WJC_METTL3_EV_vs_WT_F03.19358.19358.2 2.37E-09 17/32 R.LEASETESFGNEIYTVK.F "sp|O43148|MCES_HUMAN,tr|K7EP06|K7EP06_HUMAN" 2 1915.9051 1.24 34384 19358 2 1915.906753 958.9598 mRNA cap guanine-N7 methyltransferase OS=Homo sapiens OX=9606 GN=RNMT PE=1 SV=1 4.09 3238.4 - 477758 - - - 0.8607 - 3.645 0.679 - 831.4 1 2 0 0.0016 17 0 0 0 5.83E+06 4.70E+06 - - - 7.2354 1 221125_WJC_METTL3_EV_vs_WT_F03.19359.19359.3 4.64E-05 Dec-36 R.R[166.11]APFDLFENK[136.11].K "sp|P08238|HS90B_HUMAN,sp|Q58FF7|H90B3_HUMAN" 2 1253.6523 1.05 34385 19359 3 1253.650996 418.8914 Heat shock protein HSP 90-beta OS=Homo sapiens OX=9606 GN=HSP90AB1 PE=1 SV=4 6.07 3238.6 - 464095 - - - -1.0737 - 2.174 0.477 - 169.5 1 2 0 -0.0013 10 0 0 0 4.77E+06 4.54E+06 - - - 6.1256 0.9999 221125_WJC_METTL3_EV_vs_WT_F03.19360.19360.3 0.000274 19/48 K.LYRPPPVLDALGR.V sp|Q92616|GCN1_HUMAN 1 1465.8405 1.44 34386 19360 3 1465.842852 489.6208 eIF-2-alpha kinase activator GCN1 OS=Homo sapiens OX=9606 GN=GCN1 PE=1 SV=6 8.75 3238.7 - 383684 - - - 1.5813 - 3.074 0.356 - 597.2 1 2 0 0.0023 13 0 0 0 4.19E+06 2.91E+06 - - - 5.5531 0.9985 221125_WJC_METTL3_EV_vs_WT_F03.19361.19361.2 0.000625 28-Oct K.IIPLYSTLPPQQQQR[166.11].L sp|O43143|DHX15_HUMAN 1 1790.9918 1.19 34387 19361 2 1790.98802 896.5032 Pre-mRNA-splicing factor ATP-dependent RNA helicase DHX15 OS=Homo sapiens OX=9606 GN=DHX15 PE=1 SV=2 8.75 3238.8 - 318744 - - - -2.1323 - 1.642 0.339 - 149.5 1 2 0 -0.0038 15 0 0 0 8.81E+06 7.40E+06 - - - 2.7629 1 221125_WJC_METTL3_EV_vs_WT_F03.19368.19368.2 4.10E-06 14/24 K.GYAYTFITEDQAR.Y "sp|Q7L014|DDX46_HUMAN,tr|A0A0C4DG89|A0A0C4DG89_HUMAN" 2 1533.71 3.26 34392 19368 2 1533.709499 767.8623 Probable ATP-dependent RNA helicase DDX46 OS=Homo sapiens OX=9606 GN=DDX46 PE=1 SV=2 4.37 3239.5 - 2.42E+06 - - - -0.3091 - 2.82 0.619 - 864.7 1 2 0 -0.0005 13 0 0 0 1.05E+07 3.21E+06 - - - 6.2736 0.9973 221125_WJC_METTL3_EV_vs_WT_F03.19369.19369.3 7.92E-07 13/44 V.KMALDIEIATYR.K "sp|P08670|VIME_HUMAN,sp|P41219|PERI_HUMAN,tr|H7C5W5|H7C5W5_HUMAN,tr|B0YJC5|B0YJC5_HUMAN,tr|B0YJC4|B0YJC4_HUMAN" 5 1422.7541 2.06 34393 19369 3 1422.754326 475.2586 Vimentin OS=Homo sapiens OX=9606 GN=VIM PE=1 SV=4 6.07 3239.6 - 2.35E+06 - - - 0.1687 - 2.547 0.501 - 347.2 1 1 0 0.0002 12 0 0 0 2.47E+07 1.20E+07 - - - 6.717 0.9928 221125_WJC_METTL3_EV_vs_WT_F03.19372.19372.2 0.000154 14/30 S.SGGYGGLGGFGGGSFR.G "sp|P13645|K1C10_HUMAN,tr|A0A1B0GVI3|A0A1B0GVI3_HUMAN" 2 1431.6531 5.41 34396 19372 2 1431.653854 716.8338 "Keratin, type I cytoskeletal 10 OS=Homo sapiens OX=9606 GN=KRT10 PE=1 SV=6" 8.46 3239.7 - 1.77E+06 - - - 0.5078 - 2.339 0.528 - 436.3 1 1 0 0.0007 16 0 0 0 1.59E+07 2.94E+06 - - - 5.0297 1 221125_WJC_METTL3_EV_vs_WT_F03.19373.19373.2 7.75E-09 17/32 K.INGEAQPWLSTSTEGLK.L sp|Q7Z5L9|I2BP2_HUMAN 1 1829.9159 1.57 34397 19373 2 1829.914405 915.9652 Interferon regulatory factor 2-binding protein 2 OS=Homo sapiens OX=9606 GN=IRF2BP2 PE=1 SV=2 4.53 3239.9 - 1.77E+06 - - - -0.8405 - 3.012 0.593 - 562.9 1 2 0 -0.0015 17 0 0 0 2.83E+07 1.81E+07 - - - 6.1312 1 221125_WJC_METTL3_EV_vs_WT_F03.19374.19374.2 3.33E-10 15/24 K.NSVTPDMMEEMYK[136.11].K "sp|P46777|RL5_HUMAN,tr|A0A2R8Y6J3|A0A2R8Y6J3_HUMAN" 2 1581.6605 0.88 34398 19374 2 1581.658465 791.8375 60S ribosomal protein L5 OS=Homo sapiens OX=9606 GN=RPL5 PE=1 SV=3 4.14 3240 - 1.61E+06 - - - -1.2563 - 3.01 0.627 - 987.3 1 2 0 -0.002 13 0 0 0 1.27E+07 1.43E+07 - - - 6.4996 1 221125_WJC_METTL3_EV_vs_WT_F03.19375.19375.3 1.35E-05 Dec-52 R.VYALPEDLVEVKPK.M "sp|P13797|PLST_HUMAN,tr|A0A0A0MSQ0|A0A0A0MSQ0_HUMAN" 2 1598.892 0.57 34399 19375 3 1598.893289 533.9713 Plastin-3 OS=Homo sapiens OX=9606 GN=PLS3 PE=1 SV=4 4.68 3240.1 - 1.60E+06 - - - 0.8312 - 2.478 0.54 - 151.9 1 2 0 0.0013 14 0 0 0 1.16E+07 2.05E+07 - - - 6.9717 0.9998 221125_WJC_METTL3_EV_vs_WT_F03.19376.19376.3 0.000917 Dec-40 K.DLFDYSPPLHK.N "sp|Q9NYF8|BCLF1_HUMAN,tr|E9PKI6|E9PKI6_HUMAN,tr|A0A1W2PQ43|A0A1W2PQ43_HUMAN,tr|E9PK91|E9PK91_HUMAN,tr|E9PK09|E9PK09_HUMAN,tr|E9PQN2|E9PQN2_HUMAN" 6 1330.6558 2.61 34400 19376 3 1330.655863 444.5592 Bcl-2-associated transcription factor 1 OS=Homo sapiens OX=9606 GN=BCLAF1 PE=1 SV=2 5.21 3240.1 - 1.56E+06 - - - 0.0834 - 1.694 0.391 - 126.9 1 2 0 0.0001 11 0 0 0 3.11E+08 1.19E+08 - - - 4.3966 0.9977 221125_WJC_METTL3_EV_vs_WT_F03.19377.19377.2 0.000203 26-Dec R.FGQGSGPIVLDDVR.C "sp|Q9UGM3|DMBT1_HUMAN,sp|Q9UGM3|DMBT1_HUMAN,sp|Q9UGM3|DMBT1_HUMAN,tr|A0A590UK99|A0A590UK99_HUMAN,tr|A0A590UJF8|A0A590UJF8_HUMAN,tr|A0A590UJZ9|A0A590UJZ9_HUMAN,tr|A0A590UJZ9|A0A590UJZ9_HUMAN,tr|A0A590UJ76|A0A590UJ76_HUMAN,tr|A0A590UJ76|A0A590UJ76_HUMAN,tr|A0A590UJ76|A0A590UJ76_HUMAN,tr|A0A590UIX5|A0A590UIX5_HUMAN" 11 1458.7467 20.14 34401 19377 2 1458.751937 730.3806 Deleted in malignant brain tumors 1 protein OS=Homo sapiens OX=9606 GN=DMBT1 PE=1 SV=2 4.21 3240.3 - 1.48E+06 - - - 3.5949 - 2.407 0.306 - 505.3 1 2 0 0.0052 14 0 0 0 1.22E+07 6.05E+05 - - - 3.5037 0.9998 221125_WJC_METTL3_EV_vs_WT_F03.19379.19379.2 0.00109 22-Dec K.IGISDISSLSEK[136.11].T sp|Q5UIP0|RIF1_HUMAN 1 1255.6751 1.08 34403 19379 2 1255.676004 628.8448 Telomere-associated protein RIF1 OS=Homo sapiens OX=9606 GN=RIF1 PE=1 SV=2 4.37 3240.5 - 1.11E+06 - - - 0.7223 - 2.869 0.39 - 565.7 1 2 0 0.0009 12 0 0 0 1.09E+07 1.01E+07 - - - 4.6944 1 221125_WJC_METTL3_EV_vs_WT_F03.19380.19380.3 1.18E-07 20/44 R.FATSEELLSHLR[166.11].T "sp|Q9H7S9|ZN703_HUMAN,sp|Q96F45|ZN503_HUMAN" 2 1411.7335 1.43 34404 19380 3 1411.732964 471.5851 Zinc finger protein 703 OS=Homo sapiens OX=9606 GN=ZNF703 PE=1 SV=1 5.4 3240.6 - 1.03E+06 - - - -0.379 - 2.86 0.554 - 417.3 1 2 0 -0.0005 12 0 0 0 1.09E+09 7.65E+08 - - - 7.6291 1 221125_WJC_METTL3_EV_vs_WT_F03.19383.19383.3 5.96E-06 Oct-40 R.EHFSEVFVDLK.W sp|Q8IZH2|XRN1_HUMAN 1 1348.6663 1.76 34407 19383 3 1348.668166 450.5627 5'-3' exoribonuclease 1 OS=Homo sapiens OX=9606 GN=XRN1 PE=1 SV=1 4.65 3240.9 - 735320 - - - 1.371 - 2.195 0.516 - 129.6 1 2 0 0.0018 11 0 0 0 4.30E+06 2.44E+06 - - - 6.5258 0.9999 221125_WJC_METTL3_EV_vs_WT_F03.19384.19384.3 0.001 14/40 K.TFKPIDLSDLK.R "sp|C9JLW8|MCRI1_HUMAN,tr|I3L4Q0|I3L4Q0_HUMAN,tr|I3L2L5|I3L2L5_HUMAN" 3 1275.7075 1.24 34408 19384 3 1275.707879 426.2431 Mapk-regulated corepressor-interacting protein 1 OS=Homo sapiens OX=9606 GN=MCRIP1 PE=1 SV=1 5.63 3241.1 - 676636 - - - 0.3331 - 2.521 0.388 - 259.8 1 2 0 0.0004 11 0 0 0 7.78E+06 6.28E+06 - - - 5.4925 1 221125_WJC_METTL3_EV_vs_WT_F03.19387.19387.3 5.88E-05 13/40 K.TFK[136.11]PIDLSDLK[136.11].R "sp|C9JLW8|MCRI1_HUMAN,tr|I3L4Q0|I3L4Q0_HUMAN,tr|I3L2L5|I3L2L5_HUMAN" 3 1291.7359 1.2 34410 19387 3 1291.735196 431.5859 Mapk-regulated corepressor-interacting protein 1 OS=Homo sapiens OX=9606 GN=MCRIP1 PE=1 SV=1 5.63 3241.6 - 1.43E+06 - - - -0.5094 - 2.265 0.46 - 206.1 1 2 0 -0.0007 11 0 0 0 7.54E+06 6.28E+06 - - - 5.991 0.9986 221125_WJC_METTL3_EV_vs_WT_F03.19388.19388.2 0.0154 26-Jul K.SSWLEEDDDPVVAR[166.11].V sp|O15460|P4HA2_HUMAN 1 1626.7401 1.79 34411 19388 2 1626.73852 814.3773 Prolyl 4-hydroxylase subunit alpha-2 OS=Homo sapiens OX=9606 GN=P4HA2 PE=1 SV=1 3.77 3241.7 - 436668 - - - -0.9719 - 1.484 0.297 - 102.5 1 2 0 -0.0016 14 0 0 0 8.71E+06 4.85E+06 - - - 2.2247 1 221125_WJC_METTL3_EV_vs_WT_F03.19389.19389.3 0.00127 17/44 R.FATSEELLSHLR.T "sp|Q9H7S9|ZN703_HUMAN,sp|Q96F45|ZN503_HUMAN" 2 1401.7252 1.43 34412 19389 3 1401.725632 468.249 Zinc finger protein 703 OS=Homo sapiens OX=9606 GN=ZNF703 PE=1 SV=1 5.4 3241.7 - 1.13E+07 - - - 0.2875 - 2.648 0.477 - 268.5 1 2 0 0.0004 12 0 0 0 1.09E+09 7.63E+08 - - - 6.5572 1 221125_WJC_METTL3_EV_vs_WT_F03.19390.19390.3 2.30E-05 Dec-40 R.GFC[160.03]FLEYEDHK[136.11].T "sp|O60506|HNRPQ_HUMAN,sp|O43390|HNRPR_HUMAN,tr|A0A7I2YQV8|A0A7I2YQV8_HUMAN,tr|B4DT28|B4DT28_HUMAN,tr|A0A7I2YQN2|A0A7I2YQN2_HUMAN,tr|A0A7I2V5Q6|A0A7I2V5Q6_HUMAN,tr|A0A7I2V4Z0|A0A7I2V4Z0_HUMAN,tr|A0A6Q8PHG0|A0A6Q8PHG0_HUMAN,tr|B7Z645|B7Z645_HUMAN,tr|A0A6Q8PH31|A0A6Q8PH31_HUMAN,tr|A0A6Q8PEX7|A0A6Q8PEX7_HUMAN,tr|A0A7I2V2F2|A0A7I2V2F2_HUMAN,tr|A0A7I2V346|A0A7I2V346_HUMAN,tr|A0A7I2V309|A0A7I2V309_HUMAN" 14 1451.6271 1.14 34413 19390 3 1451.62742 484.883 Heterogeneous nuclear ribonucleoprotein Q OS=Homo sapiens OX=9606 GN=SYNCRIP PE=1 SV=2 4.65 3241.8 - 4.87E+06 - - - 0.2191 - 2.099 0.53 - 102 1 2 0 0.0003 11 0 0 0 8.85E+07 7.77E+07 - - - 6.5552 1 221125_WJC_METTL3_EV_vs_WT_F03.19391.19391.3 0.000118 Dec-40 R.GFC[160.03]FLEYEDHK.T "sp|O60506|HNRPQ_HUMAN,sp|O43390|HNRPR_HUMAN,tr|A0A7I2YQV8|A0A7I2YQV8_HUMAN,tr|B4DT28|B4DT28_HUMAN,tr|A0A7I2YQN2|A0A7I2YQN2_HUMAN,tr|A0A7I2V5Q6|A0A7I2V5Q6_HUMAN,tr|A0A7I2V4Z0|A0A7I2V4Z0_HUMAN,tr|A0A6Q8PHG0|A0A6Q8PHG0_HUMAN,tr|B7Z645|B7Z645_HUMAN,tr|A0A6Q8PH31|A0A6Q8PH31_HUMAN,tr|A0A6Q8PEX7|A0A6Q8PEX7_HUMAN,tr|A0A7I2V2F2|A0A7I2V2F2_HUMAN,tr|A0A7I2V346|A0A7I2V346_HUMAN,tr|A0A7I2V309|A0A7I2V309_HUMAN" 14 1443.6129 1.14 34414 19391 3 1443.613514 482.2116 Heterogeneous nuclear ribonucleoprotein Q OS=Homo sapiens OX=9606 GN=SYNCRIP PE=1 SV=2 4.65 3241.8 - 4.24E+06 - - - 0.4239 - 1.893 0.536 - 116.4 1 2 0 0.0006 11 0 0 0 8.87E+07 7.77E+07 - - - 6.3286 0.9999 221125_WJC_METTL3_EV_vs_WT_F03.19392.19392.2 1.40E-05 13/18 K.FAAQELIEVK[136.11].R "sp|Q86U44|MTA70_HUMAN,tr|F5H6D8|F5H6D8_HUMAN,tr|H0YFV6|H0YFV6_HUMAN,tr|B4DTN4|B4DTN4_HUMAN" 4 1154.6427 -1 34415 19392 2 1154.642806 578.3286 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 4.53 3241.9 - 3.53E+06 - - - 0.1135 - 2.465 0.469 - 448.7 1 2 0 0.0001 10 0 0 0 0.00E+00 0.00E+00 - - - 5.0233 1 221125_WJC_METTL3_EV_vs_WT_F03.19393.19393.2 3.36E-09 17/32 K.INGEAQPWLSTSTEGLK[136.11].L sp|Q7Z5L9|I2BP2_HUMAN 1 1837.9301 1.57 34416 19393 2 1837.927016 919.9723 Interferon regulatory factor 2-binding protein 2 OS=Homo sapiens OX=9606 GN=IRF2BP2 PE=1 SV=2 4.53 3241.9 - 2.87E+06 - - - -1.7014 - 3.504 0.613 - 612.1 1 2 0 -0.0031 17 0 0 0 2.83E+07 1.81E+07 - - - 6.6504 0.9999 221125_WJC_METTL3_EV_vs_WT_F03.19395.19395.3 3.30E-06 Nov-40 R.FDASFFGVHPK[136.11].Q "sp|P49327|FAS_HUMAN,tr|A0A0U1RQF0|A0A0U1RQF0_HUMAN,tr|A0A0U1RRG3|A0A0U1RRG3_HUMAN" 3 1258.6226 0.77 34418 19395 3 1258.621738 420.5481 Fatty acid synthase OS=Homo sapiens OX=9606 GN=FASN PE=1 SV=3 6.74 3242.1 - 1.78E+06 - - - -0.6912 - 2.061 0.395 - 79.9 1 2 0 -0.0009 11 0 0 0 4.64E+07 6.05E+07 - - - 4.9981 0.9996 221125_WJC_METTL3_EV_vs_WT_F03.19396.19396.2 0.00138 13/22 K.IGISDISSLSEK.T sp|Q5UIP0|RIF1_HUMAN 1 1247.6609 1.08 34419 19396 2 1247.66291 624.8377 Telomere-associated protein RIF1 OS=Homo sapiens OX=9606 GN=RIF1 PE=1 SV=2 4.37 3242.1 - 1.69E+06 - - - 1.6134 - 2.19 0.401 - 412.9 1 2 0 0.002 12 0 0 0 1.09E+07 1.01E+07 - - - 4.0647 1 221125_WJC_METTL3_EV_vs_WT_F03.19397.19397.2 1.87E-06 20-Dec K.NVDLSTFYQNR.A sp|O94826|TOM70_HUMAN 1 1355.647 1.56 34420 19397 2 1355.645916 678.8308 Mitochondrial import receptor subunit TOM70 OS=Homo sapiens OX=9606 GN=TOMM70 PE=1 SV=1 5.84 3242.2 - 1.68E+06 - - - -0.7841 - 2.472 0.578 - 529.7 1 2 0 -0.0011 11 0 0 0 1.36E+07 8.75E+06 - - - 5.7581 1 221125_WJC_METTL3_EV_vs_WT_F03.19398.19398.2 4.00E-09 14/22 K.QYEAYVQALEGK[136.11].Y "sp|Q15007|FL2D_HUMAN,tr|A0A087X1R4|A0A087X1R4_HUMAN" 2 1405.6969 0.96 34421 19398 2 1405.698526 703.8557 Pre-mRNA-splicing regulator WTAP OS=Homo sapiens OX=9606 GN=WTAP PE=1 SV=2 4.53 3242.3 - 1.61E+06 - - - 1.1596 - 2.534 0.596 - 823.9 1 2 0 0.0016 12 0 0 0 3.31E+07 3.45E+07 - - - 5.889 1 221125_WJC_METTL3_EV_vs_WT_F03.19399.19399.3 1.99E-08 16/40 R.FDASFFGVHPK.Q "sp|P49327|FAS_HUMAN,tr|A0A0U1RQF0|A0A0U1RQF0_HUMAN,tr|A0A0U1RRG3|A0A0U1RRG3_HUMAN" 3 1250.6084 0.77 34422 19399 3 1250.608528 417.8767 Fatty acid synthase OS=Homo sapiens OX=9606 GN=FASN PE=1 SV=3 6.74 3242.4 - 1.09E+06 - - - 0.096 - 2.507 0.561 - 180.6 1 2 0 0.0001 11 0 0 0 4.64E+07 6.06E+07 - - - 7.4055 0.9999 221125_WJC_METTL3_EV_vs_WT_F03.19401.19401.2 4.02E-05 18-Nov K.NMQNAEEWFK.S sp|P07196|NFL_HUMAN 1 1295.5605 5.26 34424 19401 2 1295.561478 648.7875 Neurofilament light polypeptide OS=Homo sapiens OX=9606 GN=NEFL PE=1 SV=3 4.53 3242.6 - 818992 - - - 0.7765 - 2.142 0.593 - 375.4 1 2 0 0.001 10 0 0 0 2.22E+07 4.22E+06 - - - 5.5468 0.8148 221125_WJC_METTL3_EV_vs_WT_F03.19402.19402.2 0.378 24-Jul K.AFAQNAALTR[166.11]HER[166.11].L sp|Q8NCK3|ZN485_HUMAN 1 1503.7809 0.001 34425 19402 2 1503.784664 752.8978 Zinc finger protein 485 OS=Homo sapiens OX=9606 GN=ZNF485 PE=1 SV=1 9.65 3242.8 - 804775 - - - 2.4704 - 1.511 0.131 - 152 2 2 1 0.0037 13 0 0 0 0.00E+00 6.36E+07 - - - 0.9323 0.9987 221125_WJC_METTL3_EV_vs_WT_F03.19404.19404.3 0.000491 Dec-40 R.DKLNNLVLFDK.A sp|P62851|RS25_HUMAN 1 1317.7293 1.26 34427 19404 3 1317.731163 440.2504 40S ribosomal protein S25 OS=Homo sapiens OX=9606 GN=RPS25 PE=1 SV=1 5.96 3243 - 635953 - - - 1.4502 - 2.252 0.334 - 280.8 1 2 1 0.0019 11 0 0 0 2.07E+08 1.63E+08 - - - 4.5695 0.9999 221125_WJC_METTL3_EV_vs_WT_F03.19405.19405.2 7.97E-07 Oct-32 R.LEASETESFGNEIYTVK[136.11].F "sp|O43148|MCES_HUMAN,tr|K7EP06|K7EP06_HUMAN" 2 1923.9193 1.24 34428 19405 2 1923.91958 962.9669 mRNA cap guanine-N7 methyltransferase OS=Homo sapiens OX=9606 GN=RNMT PE=1 SV=1 4.09 3243.2 - 598676 - - - 0.1435 - 2.301 0.57 - 232.1 1 2 0 0.0003 17 0 0 0 5.83E+06 4.70E+06 - - - 5.2997 0.999 221125_WJC_METTL3_EV_vs_WT_F03.19406.19406.3 0.00159 Sep-48 K.GYAYTFITEDQAR.Y "sp|Q7L014|DDX46_HUMAN,tr|A0A0C4DG89|A0A0C4DG89_HUMAN" 2 1533.71 2.09 34429 19406 3 1533.710981 512.2439 Probable ATP-dependent RNA helicase DDX46 OS=Homo sapiens OX=9606 GN=DDX46 PE=1 SV=2 4.37 3243.3 - 590681 - - - 0.6572 - 1.713 0.294 - 73.5 1 2 0 0.001 13 0 0 0 3.93E+06 1.88E+06 - - - 3.2769 1 221125_WJC_METTL3_EV_vs_WT_F03.19408.19408.2 5.76E-10 17/30 R.TPAVEGLTEAEEEELR.A "sp|O43399|TPD54_HUMAN,tr|A0A087WZ51|A0A087WZ51_HUMAN,tr|A0A087WYR3|A0A087WYR3_HUMAN" 3 1771.8476 4.76 34430 19408 2 1771.847424 886.9311 Tumor protein D54 OS=Homo sapiens OX=9606 GN=TPD52L2 PE=1 SV=2 3.9 3243.5 - 1.30E+06 - - - -0.0931 - 3.589 0.598 - 982.2 1 2 0 -0.0002 16 0 0 0 1.26E+07 2.64E+06 - - - 6.5995 0.9999 221125_WJC_METTL3_EV_vs_WT_F03.19410.19410.2 0.0212 13/20 K.NSLESYAFNMK[136.11].A "sp|P11142|HSP7C_HUMAN,tr|E9PNE6|E9PNE6_HUMAN,tr|A8K7Q2|A8K7Q2_HUMAN,tr|E9PKE3|E9PKE3_HUMAN,tr|E9PM13|E9PM13_HUMAN,tr|E9PS65|E9PS65_HUMAN" 6 1310.6056 0.15 34432 19410 2 1310.60451 656.3101 Heat shock cognate 71 kDa protein OS=Homo sapiens OX=9606 GN=HSPA8 PE=1 SV=1 6 3243.6 - 7.78E+06 - - - -0.8607 - 2.625 0.474 - 951.4 1 2 0 -0.0011 11 0 0 0 8.03E+08 5.50E+09 - - - 5.1524 1 221125_WJC_METTL3_EV_vs_WT_F03.19411.19411.2 5.58E-06 22-Dec R.FATSEELLSHLR.T "sp|Q9H7S9|ZN703_HUMAN,sp|Q96F45|ZN503_HUMAN" 2 1401.7252 1.41 34433 19411 2 1401.724699 701.8699 Zinc finger protein 703 OS=Homo sapiens OX=9606 GN=ZNF703 PE=1 SV=1 5.4 3243.7 - 6.10E+06 - - - -0.3781 - 2.81 0.602 - 640.4 1 2 0 -0.0005 12 0 0 0 1.37E+08 9.70E+07 - - - 6.2057 0.9994 221125_WJC_METTL3_EV_vs_WT_F03.19412.19412.3 0.000351 Nov-52 K.QLEAIDQLHLEYAK.R "sp|O43707|ACTN4_HUMAN,tr|F5GXS2|F5GXS2_HUMAN,tr|H7C144|H7C144_HUMAN" 3 1669.8675 0.98 34434 19412 3 1669.862744 557.6298 Alpha-actinin-4 OS=Homo sapiens OX=9606 GN=ACTN4 PE=1 SV=2 4.65 3243.7 - 4.35E+06 - - - -2.8697 - 2.253 0.351 - 160.1 1 2 0 -0.0048 14 0 0 0 2.31E+07 2.36E+07 - - - 4.6106 1 221125_WJC_METTL3_EV_vs_WT_F03.19414.19414.2 7.67E-05 16/20 R.DKLNNLVLFDK.A sp|P62851|RS25_HUMAN 1 1317.7293 1.34 34436 19414 2 1317.729067 659.8719 40S ribosomal protein S25 OS=Homo sapiens OX=9606 GN=RPS25 PE=1 SV=1 5.96 3243.9 - 2.43E+06 - - - -0.1404 - 3.195 0.538 - 935.2 1 2 1 -0.0002 11 0 0 0 1.49E+08 1.11E+08 - - - 6.157 0.999 221125_WJC_METTL3_EV_vs_WT_F03.19415.19415.2 3.13E-06 14/20 R.DK[136.11]LNNLVLFDK[136.11].A sp|P62851|RS25_HUMAN 1 1333.7577 1.34 34437 19415 2 1333.757263 667.8861 40S ribosomal protein S25 OS=Homo sapiens OX=9606 GN=RPS25 PE=1 SV=1 5.96 3243.9 - 2.36E+06 - - - -0.2917 - 2.997 0.469 - 671.1 1 2 1 -0.0004 11 0 0 0 1.49E+08 1.11E+08 - - - 5.4742 0.9974 221125_WJC_METTL3_EV_vs_WT_F03.19416.19416.2 0.000441 20-Nov R.HFEELETIMDR.E "sp|Q8TAQ2|SMRC2_HUMAN,sp|Q92922|SMRC1_HUMAN,tr|F8VXC8|F8VXC8_HUMAN" 3 1418.65 4.24 34438 19416 2 1418.642407 710.3323 SWI\SNF complex subunit SMARCC2 OS=Homo sapiens OX=9606 GN=SMARCC2 PE=1 SV=1 4.4 3244 - 2.05E+06 - - - -5.3628 - 2.268 0.53 - 384.8 1 2 0 -0.0076 11 0 0 0 1.56E+07 3.67E+06 - - - 5.1685 1 221125_WJC_METTL3_EV_vs_WT_F03.19417.19417.3 1.05E-09 21/68 C.IYSALILHDDEVTVTEDK.L sp|P05386|RLA1_HUMAN 1 2060.0314 0.54 34439 19417 3 2060.031684 687.6844 60S acidic ribosomal protein P1 OS=Homo sapiens OX=9606 GN=RPLP1 PE=1 SV=1 4.1 3244.1 - 1.80E+06 - - - 0.1539 - 3.8 0.626 - 528.4 1 1 0 0.0003 18 0 0 0 8.59E+06 1.58E+07 - - - 8.8435 0.9609 221125_WJC_METTL3_EV_vs_WT_F03.19418.19418.2 0.778 18-Jul K.NMQNAEEWFK[136.11].S sp|P07196|NFL_HUMAN 1 1303.5747 4.39 34440 19418 2 1303.580305 652.7946 Neurofilament light polypeptide OS=Homo sapiens OX=9606 GN=NEFL PE=1 SV=3 4.53 3244.1 - 1.20E+06 - - - 4.3212 - 1.545 0.173 - 166.6 2 2 0 0.0056 10 0 0 0 1.86E+07 4.22E+06 - - - 1.3968 1 221125_WJC_METTL3_EV_vs_WT_F03.19423.19423.2 1.14E-05 26-Dec K.SPASDTYIVFGEAK[136.11].L "sp|E9PAV3|NACAM_HUMAN,sp|Q13765|NACA_HUMAN,tr|A0A7I2V473|A0A7I2V473_HUMAN,tr|F8VZJ2|F8VZJ2_HUMAN,tr|F8VNW4|F8VNW4_HUMAN,tr|A0A7I2V2K5|A0A7I2V2K5_HUMAN,tr|F8W0W4|F8W0W4_HUMAN,tr|H0YHX9|H0YHX9_HUMAN" 8 1491.7337 0.55 34443 19423 2 1491.731245 746.8741 "Nascent polypeptide-associated complex subunit alpha, muscle-specific form OS=Homo sapiens OX=9606 GN=NACA PE=1 SV=1" 4.37 3244.8 - 2.15E+07 - - - -1.629 - 2.749 0.598 - 493.4 1 2 0 -0.0024 14 0 0 0 1.38E+08 2.52E+08 - - - 5.9947 0.9997 221125_WJC_METTL3_EV_vs_WT_F03.19424.19424.3 1.59E-05 Dec-40 R.DK[136.11]LNNLVLFDK[136.11].A sp|P62851|RS25_HUMAN 1 1333.7577 1.26 34444 19424 3 1333.755579 445.5932 40S ribosomal protein S25 OS=Homo sapiens OX=9606 GN=RPS25 PE=1 SV=1 5.96 3244.8 - 8.18E+06 - - - -1.5543 - 2.185 0.474 - 309.1 1 2 1 -0.0021 11 0 0 0 2.06E+08 1.63E+08 - - - 6.0445 1 221125_WJC_METTL3_EV_vs_WT_F03.19425.19425.3 1.03E-05 Nov-52 K.SPASDTYIVFGEAK.L "sp|E9PAV3|NACAM_HUMAN,sp|Q13765|NACA_HUMAN,tr|A0A7I2V473|A0A7I2V473_HUMAN,tr|F8VZJ2|F8VZJ2_HUMAN,tr|F8VNW4|F8VNW4_HUMAN,tr|A0A7I2V2K5|A0A7I2V2K5_HUMAN,tr|F8W0W4|F8W0W4_HUMAN,tr|H0YHX9|H0YHX9_HUMAN" 8 1483.7195 0.57 34445 19425 3 1483.71758 495.5804 "Nascent polypeptide-associated complex subunit alpha, muscle-specific form OS=Homo sapiens OX=9606 GN=NACA PE=1 SV=1" 4.37 3244.9 - 3.81E+06 - - - -1.2772 - 2.009 0.51 - 124.7 1 2 0 -0.0019 14 0 0 0 2.87E+07 5.08E+07 - - - 6.0795 1 221125_WJC_METTL3_EV_vs_WT_F03.19427.19427.3 2.85E-07 13/52 R.LIVDHNIADYMTAK.N "sp|Q6P2Q9|PRP8_HUMAN,tr|I3L0J9|I3L0J9_HUMAN" 2 1602.8076 1.66 34447 19427 3 1602.804911 535.2765 Pre-mRNA-processing-splicing factor 8 OS=Homo sapiens OX=9606 GN=PRPF8 PE=1 SV=2 5.21 3245 - 2.82E+06 - - - -1.6646 - 2.555 0.591 - 190.4 1 2 0 -0.0027 14 0 0 0 4.26E+07 2.56E+07 - - - 7.6212 0.9415 221125_WJC_METTL3_EV_vs_WT_F03.19430.19430.2 0.023 30-Aug R.LQAQVEELQAQVEQLR.G sp|Q86X02|CDR2L_HUMAN 1 1880.9956 999 34450 19430 2 1881.005348 941.5051 Cerebellar degeneration-related protein 2-like OS=Homo sapiens OX=9606 GN=CDR2L PE=1 SV=2 4.25 3245.2 - 2.15E+06 - - - 5.1877 - 1.54 0.196 - 139.9 1 2 0 0.0098 16 0 0 0 2.10E+07 0.00E+00 - - - 1.5471 0.9991 221125_WJC_METTL3_EV_vs_WT_F03.19431.19431.2 0.000123 16/24 R.IANLQTDLSDGLR[166.11].L "sp|P21333|FLNA_HUMAN,tr|A0A7P0NMY4|A0A7P0NMY4_HUMAN,tr|Q60FE5|Q60FE5_HUMAN,tr|A0A7I2V3E6|A0A7I2V3E6_HUMAN,tr|A0A087WWY3|A0A087WWY3_HUMAN,tr|F8WE98|F8WE98_HUMAN" 6 1424.7499 1.35 34451 19431 2 1424.744656 713.3822 Filamin-A OS=Homo sapiens OX=9606 GN=FLNA PE=1 SV=4 4.21 3245.4 - 1.82E+06 - - - -3.6645 - 3.054 0.384 - 1196.5 1 2 0 -0.0052 13 0 0 0 3.72E+07 2.76E+07 - - - 4.741 1 221125_WJC_METTL3_EV_vs_WT_F03.19432.19432.3 2.39E-07 14/48 K.LSLSFALADGSHK[136.11].N "sp|Q6L8Q7|PDE12_HUMAN,tr|F6T1Q0|F6T1Q0_HUMAN" 2 1352.718 0.78 34452 19432 3 1352.715464 451.9133 "2',5'-phosphodiesterase 12 OS=Homo sapiens OX=9606 GN=PDE12 PE=1 SV=2" 6.74 3245.4 - 1.56E+06 - - - -1.8489 - 2.502 0.542 - 246.9 1 2 0 -0.0025 13 0 0 0 2.24E+07 2.88E+07 - - - 7.0686 0.9996 221125_WJC_METTL3_EV_vs_WT_F03.19433.19433.3 3.21E-05 15/48 K.LSLSFALADGSHK.N "sp|Q6L8Q7|PDE12_HUMAN,tr|F6T1Q0|F6T1Q0_HUMAN" 2 1344.7038 0.78 34453 19433 3 1344.698611 449.2419 "2',5'-phosphodiesterase 12 OS=Homo sapiens OX=9606 GN=PDE12 PE=1 SV=2" 6.74 3245.5 - 1.52E+06 - - - -3.8328 - 2.541 0.422 - 239.4 1 2 0 -0.0052 13 0 0 0 2.24E+07 2.88E+07 - - - 5.7719 1 221125_WJC_METTL3_EV_vs_WT_F03.19434.19434.2 2.44E-10 15/28 K.VIGIEC[160.03]SSISDYAVK.L "sp|Q99873|ANM1_HUMAN,tr|E9PQ98|E9PQ98_HUMAN,tr|E9PKG1|E9PKG1_HUMAN,tr|E9PNR9|E9PNR9_HUMAN,tr|H0YDE4|H0YDE4_HUMAN,tr|E9PMW9|E9PMW9_HUMAN,tr|E9PIX6|E9PIX6_HUMAN" 7 1639.8127 1.66 34454 19434 2 1639.81341 820.9136 Protein arginine N-methyltransferase 1 OS=Homo sapiens OX=9606 GN=PRMT1 PE=1 SV=3 4.37 3245.6 - 1.37E+06 - - - 0.4183 - 2.779 0.644 - 593.1 1 2 0 0.0007 15 0 0 0 4.37E+07 2.63E+07 - - - 6.3102 0.9991 221125_WJC_METTL3_EV_vs_WT_F03.19436.19436.2 2.63E-06 20-Oct R.GFC[160.03]FLEYEDHK.T "sp|O60506|HNRPQ_HUMAN,sp|O43390|HNRPR_HUMAN,tr|A0A7I2YQV8|A0A7I2YQV8_HUMAN,tr|B4DT28|B4DT28_HUMAN,tr|A0A7I2YQN2|A0A7I2YQN2_HUMAN,tr|A0A7I2V5Q6|A0A7I2V5Q6_HUMAN,tr|A0A7I2V4Z0|A0A7I2V4Z0_HUMAN,tr|A0A6Q8PHG0|A0A6Q8PHG0_HUMAN,tr|B7Z645|B7Z645_HUMAN,tr|A0A6Q8PH31|A0A6Q8PH31_HUMAN,tr|A0A6Q8PEX7|A0A6Q8PEX7_HUMAN,tr|A0A7I2V2F2|A0A7I2V2F2_HUMAN,tr|A0A7I2V346|A0A7I2V346_HUMAN,tr|A0A7I2V309|A0A7I2V309_HUMAN" 14 1443.6129 0.98 34456 19436 2 1443.607012 722.8137 Heterogeneous nuclear ribonucleoprotein Q OS=Homo sapiens OX=9606 GN=SYNCRIP PE=1 SV=2 4.65 3245.9 - 1.19E+06 - - - -4.08 - 2.075 0.588 - 195.3 1 2 0 -0.0059 11 0 0 0 7.41E+06 7.53E+06 - - - 5.3568 0.9998 221125_WJC_METTL3_EV_vs_WT_F03.19437.19437.2 0.00753 13/22 R.NELSGALTGLTR[166.11].V sp|P26639|SYTC_HUMAN 1 1240.6651 0.38 34457 19437 2 1240.664126 621.3398 "Threonine--tRNA ligase 1, cytoplasmic OS=Homo sapiens OX=9606 GN=TARS1 PE=1 SV=3" 6 3246 - 1.13E+06 - - - -0.773 - 2.124 0.402 - 691.4 1 2 0 -0.001 12 0 0 0 7.93E+06 2.10E+07 - - - 3.9919 1 221125_WJC_METTL3_EV_vs_WT_F03.19438.19438.2 4.52E-09 20-Nov R.GFC[160.03]FLEYEDHK[136.11].T "sp|O60506|HNRPQ_HUMAN,sp|O43390|HNRPR_HUMAN,tr|A0A7I2YQV8|A0A7I2YQV8_HUMAN,tr|B4DT28|B4DT28_HUMAN,tr|A0A7I2YQN2|A0A7I2YQN2_HUMAN,tr|A0A7I2V5Q6|A0A7I2V5Q6_HUMAN,tr|A0A7I2V4Z0|A0A7I2V4Z0_HUMAN,tr|A0A6Q8PHG0|A0A6Q8PHG0_HUMAN,tr|B7Z645|B7Z645_HUMAN,tr|A0A6Q8PH31|A0A6Q8PH31_HUMAN,tr|A0A6Q8PEX7|A0A6Q8PEX7_HUMAN,tr|A0A7I2V2F2|A0A7I2V2F2_HUMAN,tr|A0A7I2V346|A0A7I2V346_HUMAN,tr|A0A7I2V309|A0A7I2V309_HUMAN" 14 1451.6271 0.98 34458 19438 2 1451.625672 726.8208 Heterogeneous nuclear ribonucleoprotein Q OS=Homo sapiens OX=9606 GN=SYNCRIP PE=1 SV=2 4.65 3246.1 - 1.03E+06 - - - -0.9851 - 2.306 0.626 - 405.2 1 2 0 -0.0014 11 0 0 0 7.41E+06 7.53E+06 - - - 5.9245 0.9997 221125_WJC_METTL3_EV_vs_WT_F03.19440.19440.2 9.61E-06 14/26 R.IQGLTVEQAEAVVR[166.11].L "sp|Q14204|DYHC1_HUMAN,tr|A0A7P0T8N2|A0A7P0T8N2_HUMAN,tr|A0A7P0T9C4|A0A7P0T9C4_HUMAN,tr|A0A7P0TBJ7|A0A7P0TBJ7_HUMAN,tr|A0A2R8Y706|A0A2R8Y706_HUMAN,tr|A0A7P0T916|A0A7P0T916_HUMAN,tr|A0A7P0TB75|A0A7P0TB75_HUMAN,tr|A0A7P0TAF3|A0A7P0TAF3_HUMAN,tr|A0A7P0TAW9|A0A7P0TAW9_HUMAN,tr|A0A7P0TA13|A0A7P0TA13_HUMAN,tr|A0A7P0T7V5|A0A7P0T7V5_HUMAN,tr|A0A7P0T9R4|A0A7P0T9R4_HUMAN,tr|A0A2R8Y5T0|A0A2R8Y5T0_HUMAN" 13 1521.839 0.59 34460 19440 2 1521.836462 761.9268 Cytoplasmic dynein 1 heavy chain 1 OS=Homo sapiens OX=9606 GN=DYNC1H1 PE=1 SV=5 4.53 3246.4 - 856513 - - - -1.6855 - 2.765 0.379 - 747.2 1 2 0 -0.0026 14 0 0 0 7.37E+06 1.26E+07 - - - 4.3917 1 221125_WJC_METTL3_EV_vs_WT_F03.19442.19442.2 7.08E-07 16/32 R.VEAGDVIYIEANSGAVK[136.11].R "sp|Q9Y265|RUVB1_HUMAN,tr|H7C4I3|H7C4I3_HUMAN,tr|E7ETR0|E7ETR0_HUMAN" 3 1741.8978 0.47 34462 19442 2 1741.898233 871.9562 RuvB-like 1 OS=Homo sapiens OX=9606 GN=RUVBL1 PE=1 SV=1 4.14 3246.6 - 556246 - - - 0.2601 - 3.214 0.572 - 770.8 1 2 0 0.0005 17 0 0 0 2.35E+06 4.98E+06 - - - 6.136 0.9997 221125_WJC_METTL3_EV_vs_WT_F03.19446.19446.2 0.000179 15/26 K.SPASDTYIVFGEAK.L "sp|E9PAV3|NACAM_HUMAN,sp|Q13765|NACA_HUMAN,tr|A0A7I2V473|A0A7I2V473_HUMAN,tr|F8VZJ2|F8VZJ2_HUMAN,tr|F8VNW4|F8VNW4_HUMAN,tr|A0A7I2V2K5|A0A7I2V2K5_HUMAN,tr|F8W0W4|F8W0W4_HUMAN,tr|H0YHX9|H0YHX9_HUMAN" 8 1483.7195 0.55 34464 19446 2 1483.715844 742.867 "Nascent polypeptide-associated complex subunit alpha, muscle-specific form OS=Homo sapiens OX=9606 GN=NACA PE=1 SV=1" 4.37 3247.1 - 9.23E+06 - - - -2.4472 - 3.128 0.486 - 855.8 1 2 0 -0.0036 14 0 0 0 1.38E+08 2.52E+08 - - - 5.4912 1 221125_WJC_METTL3_EV_vs_WT_F03.19449.19449.2 1.16E-06 14/18 A.TSEELLSHLR.T "sp|Q9H7S9|ZN703_HUMAN,sp|Q96F45|ZN503_HUMAN" 2 1183.6197 3.12 34467 19449 2 1183.618572 592.8171 Zinc finger protein 703 OS=Homo sapiens OX=9606 GN=ZNF703 PE=1 SV=1 5.37 3247.2 - 4.22E+06 - - - -0.9539 - 3.022 0.553 - 1246.8 1 1 0 -0.0011 10 0 0 0 6.19E+07 1.98E+07 - - - 6.2121 1 221125_WJC_METTL3_EV_vs_WT_F03.19451.19451.2 1.34E-06 14/18 A.TSEELLSHLR[166.11].T "sp|Q9H7S9|ZN703_HUMAN,sp|Q96F45|ZN503_HUMAN" 2 1193.628 2.71 34469 19451 2 1193.624548 597.8213 Zinc finger protein 703 OS=Homo sapiens OX=9606 GN=ZNF703 PE=1 SV=1 5.37 3247.4 - 2.37E+06 - - - -2.8677 - 2.688 0.535 - 1005 1 1 0 -0.0034 10 0 0 0 5.38E+07 1.98E+07 - - - 5.7515 1 221125_WJC_METTL3_EV_vs_WT_F03.19452.19452.2 1.20E-10 17/28 K.VIGIEC[160.03]SSISDYAVK[136.11].L "sp|Q99873|ANM1_HUMAN,tr|E9PQ98|E9PQ98_HUMAN,tr|E9PKG1|E9PKG1_HUMAN,tr|E9PNR9|E9PNR9_HUMAN,tr|H0YDE4|H0YDE4_HUMAN,tr|E9PMW9|E9PMW9_HUMAN,tr|E9PIX6|E9PIX6_HUMAN" 7 1647.8269 1.66 34470 19452 2 1647.825161 824.9207 Protein arginine N-methyltransferase 1 OS=Homo sapiens OX=9606 GN=PRMT1 PE=1 SV=3 4.37 3247.5 - 2.10E+06 - - - -1.0699 - 3.025 0.648 - 902 1 2 0 -0.0018 15 0 0 0 4.37E+07 2.63E+07 - - - 6.548 0.9998 221125_WJC_METTL3_EV_vs_WT_F03.19453.19453.3 4.18E-06 13/40 K.NSLESYAFNMK[136.11].A "sp|P11142|HSP7C_HUMAN,tr|E9PNE6|E9PNE6_HUMAN,tr|A8K7Q2|A8K7Q2_HUMAN,tr|E9PKE3|E9PKE3_HUMAN,tr|E9PM13|E9PM13_HUMAN,tr|E9PS65|E9PS65_HUMAN" 6 1310.6056 0.12 34471 19453 3 1310.603643 437.8758 Heat shock cognate 71 kDa protein OS=Homo sapiens OX=9606 GN=HSPA8 PE=1 SV=1 6 3247.6 - 2.02E+06 - - - -1.5222 - 2.423 0.345 - 170.1 1 2 0 -0.002 11 0 0 0 6.16E+06 4.99E+07 - - - 4.9 1 221125_WJC_METTL3_EV_vs_WT_F03.19457.19457.2 4.70E-13 14/32 K.TDMDNQIVVSDYAQMDR[166.11].V sp|P50991|TCPD_HUMAN 1 2009.8698 0.19 34475 19457 2 2009.871263 1005.9422 T-complex protein 1 subunit delta OS=Homo sapiens OX=9606 GN=CCT4 PE=1 SV=4 3.77 3248.1 - 975433 - - - 0.7224 - 3.459 0.726 - 479.6 1 2 0 0.0015 17 0 0 0 5.47E+06 2.90E+07 - - - 7.4538 0.9999 221125_WJC_METTL3_EV_vs_WT_F03.19458.19458.2 3.20E-05 15/28 R.SIQEAPAVSEDLVIR.L tr|J3KN66|J3KN66_HUMAN 1 1625.8625 0.98 34476 19458 2 1625.86269 813.9385 Torsin-1A-interacting protein 1 OS=Homo sapiens OX=9606 GN=TOR1AIP1 PE=1 SV=1 4.14 3248.2 - 963260 - - - 0.147 - 2.884 0.547 - 513.4 1 2 0 0.0002 15 0 0 0 8.52E+06 8.69E+06 - - - 5.6851 1 221125_WJC_METTL3_EV_vs_WT_F03.19459.19459.2 6.11E-10 18/32 K.NGVQAMVEFDSVQSAQR[166.11].A "sp|P14866|HNRPL_HUMAN,tr|M0QYL7|M0QYL7_HUMAN,tr|B4DVF8|B4DVF8_HUMAN,tr|M0R1W6|M0R1W6_HUMAN,tr|A0A3B3ITJ4|A0A3B3ITJ4_HUMAN,tr|M0QXS5|M0QXS5_HUMAN" 6 1874.882 1.56 34477 19459 2 1874.873676 938.4483 Heterogeneous nuclear ribonucleoprotein L OS=Homo sapiens OX=9606 GN=HNRNPL PE=1 SV=2 4.37 3248.4 - 963068 - - - -4.4563 - 2.951 0.628 - 387.7 1 2 0 -0.0084 17 0 0 0 3.49E+07 2.25E+07 - - - 6.3373 0.9945 221125_WJC_METTL3_EV_vs_WT_F03.19461.19461.3 0.703 13/36 K.FAAQELIEVK[136.11].R "sp|Q86U44|MTA70_HUMAN,tr|F5H6D8|F5H6D8_HUMAN,tr|H0YFV6|H0YFV6_HUMAN,tr|B4DTN4|B4DTN4_HUMAN" 4 1154.6427 0.001 34479 19461 3 1154.640409 385.8882 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 4.53 3248.6 - 895597 - - - -1.9625 - 2.04 0.171 - 203.3 1 2 0 -0.0023 10 0 0 0 0.00E+00 1.52E+07 - - - 2.528 1 221125_WJC_METTL3_EV_vs_WT_F03.19467.19467.3 2.62E-08 16/64 K.NGVQAMVEFDSVQSAQR.A "sp|P14866|HNRPL_HUMAN,tr|M0QYL7|M0QYL7_HUMAN,tr|B4DVF8|B4DVF8_HUMAN,tr|M0R1W6|M0R1W6_HUMAN,tr|A0A3B3ITJ4|A0A3B3ITJ4_HUMAN,tr|M0QXS5|M0QXS5_HUMAN" 6 1864.8738 1.27 34483 19467 3 1864.870908 622.6319 Heterogeneous nuclear ribonucleoprotein L OS=Homo sapiens OX=9606 GN=HNRNPL PE=1 SV=2 4.37 3249.3 - 3.04E+06 - - - -1.5299 - 3.049 0.59 - 351.8 1 2 0 -0.0029 17 0 0 0 3.52E+07 2.78E+07 - - - 7.9335 0.9994 221125_WJC_METTL3_EV_vs_WT_F03.19469.19469.3 0.0217 14/48 K.K[136.11]YPYWPHQPIENL.- sp|O75947|ATP5H_HUMAN 1 1691.8551 1.57 34485 19469 3 1691.851475 564.959 "ATP synthase subunit d, mitochondrial OS=Homo sapiens OX=9606 GN=ATP5PD PE=1 SV=3" 6.75 3249.5 - 2.09E+06 - - - -2.1592 - 2.375 0.303 - 175.6 1 2 0 -0.0037 13 0 0 0 4.50E+07 2.87E+07 - - - 4.2624 1 221125_WJC_METTL3_EV_vs_WT_F03.19470.19470.3 1.94E-09 16/48 R.LPPVLSHPIFDNR[166.11].A "sp|Q04206|TF65_HUMAN,tr|E9PKV4|E9PKV4_HUMAN,tr|A0A087WVP0|A0A087WVP0_HUMAN,tr|A0A087X0W8|A0A087X0W8_HUMAN,tr|E9PQS6|E9PQS6_HUMAN,tr|E9PKH5|E9PKH5_HUMAN,tr|E9PI38|E9PI38_HUMAN,tr|Q2TAM5|Q2TAM5_HUMAN" 8 1513.8281 0.01 34486 19470 3 1513.827365 505.6166 Transcription factor p65 OS=Homo sapiens OX=9606 GN=RELA PE=1 SV=2 6.74 3249.6 - 1.72E+06 - - - -0.4644 - 3.201 0.501 - 402.1 1 2 0 -0.0007 13 0 0 0 1.02E+05 1.78E+07 - - - 7.2799 0.9999 221125_WJC_METTL3_EV_vs_WT_F03.19472.19472.3 3.84E-05 13/48 R.AIADHLFWSEETK.S "sp|Q96GA3|LTV1_HUMAN,tr|A0A075B6Q4|A0A075B6Q4_HUMAN" 2 1545.7464 1.08 34488 19472 3 1545.744945 516.2561 Protein LTV1 homolog OS=Homo sapiens OX=9606 GN=LTV1 PE=1 SV=1 4.65 3249.9 - 1.44E+06 - - - -0.9141 - 2.107 0.435 - 187 1 2 0 -0.0014 13 0 0 0 1.46E+07 1.35E+07 - - - 5.4101 0.9903 221125_WJC_METTL3_EV_vs_WT_F03.19473.19473.2 2.46E-05 20-Dec F.ATSEELLSHLR[166.11].T "sp|Q9H7S9|ZN703_HUMAN,sp|Q96F45|ZN503_HUMAN" 2 1264.6651 2.96 34489 19473 2 1264.663354 633.3398 Zinc finger protein 703 OS=Homo sapiens OX=9606 GN=ZNF703 PE=1 SV=1 5.4 3250 - 1.39E+06 - - - -1.3687 - 2.479 0.471 - 787.7 1 1 0 -0.0017 11 0 0 0 3.36E+07 1.14E+07 - - - 4.9752 1 221125_WJC_METTL3_EV_vs_WT_F03.19474.19474.2 4.56E-12 21/32 R.TLSADASVNTLPVVVSR[166.11].E "sp|Q92615|LAR4B_HUMAN,tr|H0Y641|H0Y641_HUMAN,tr|H0Y4V9|H0Y4V9_HUMAN" 3 1737.95 1.25 34490 19474 2 1737.942024 869.9823 La-related protein 4B OS=Homo sapiens OX=9606 GN=LARP4B PE=1 SV=3 5.5 3250.1 - 1.29E+06 - - - -4.6089 - 3.704 0.666 - 1259.1 1 2 0 -0.008 17 0 0 0 3.96E+08 3.17E+08 - - - 7.1768 1 221125_WJC_METTL3_EV_vs_WT_F03.19480.19480.3 1.45E-10 19/64 K.VAGHSLGYGFVNYVTAK.D "sp|Q15717|ELAV1_HUMAN,tr|M0QZR9|M0QZR9_HUMAN" 2 1781.9101 1.28 34494 19480 3 1781.908188 594.9773 ELAV-like protein 1 OS=Homo sapiens OX=9606 GN=ELAVL1 PE=1 SV=2 8.48 3250.7 - 4.66E+06 - - - -1.0562 - 3.513 0.627 - 525.9 1 2 0 -0.0019 17 0 0 0 1.80E+08 1.41E+08 - - - 8.7041 1 221125_WJC_METTL3_EV_vs_WT_F03.19481.19481.2 2.00E-09 22/32 R.TLSADASVNTLPVVVSR.E "sp|Q92615|LAR4B_HUMAN,tr|H0Y641|H0Y641_HUMAN,tr|H0Y4V9|H0Y4V9_HUMAN" 3 1727.9418 1.25 34495 19481 2 1727.94181 864.9782 La-related protein 4B OS=Homo sapiens OX=9606 GN=LARP4B PE=1 SV=3 5.5 3250.8 - 3.78E+06 - - - 0.0266 - 3.618 0.654 - 1492.5 1 2 0 0 17 0 0 0 3.95E+08 3.17E+08 - - - 7.0329 1 221125_WJC_METTL3_EV_vs_WT_F03.19482.19482.2 1.17E-09 19/26 R.C[160.03]ESGFIEELPEETR.S "sp|Q9BV68|RN126_HUMAN,tr|U3KQF4|U3KQF4_HUMAN,tr|K7EIY6|K7EIY6_HUMAN" 3 1694.7458 2.13 34496 19482 2 1694.742517 848.3802 E3 ubiquitin-protein ligase RNF126 OS=Homo sapiens OX=9606 GN=RNF126 PE=1 SV=2 3.98 3250.9 - 3.74E+06 - - - -1.9171 - 3.288 0.705 - 1516.2 1 2 0 -0.0032 14 0 0 0 4.40E+07 2.06E+07 - - - 7.2341 1 221125_WJC_METTL3_EV_vs_WT_F03.19483.19483.2 1.71E-14 22/30 R.PSGEAFVELESEDEVK.L "sp|P31943|HNRH1_HUMAN,tr|E7EQJ0|E7EQJ0_HUMAN,tr|D6RIH9|D6RIH9_HUMAN,tr|D6RJ04|D6RJ04_HUMAN,tr|D6RFM3|D6RFM3_HUMAN,tr|E9PCY7|E9PCY7_HUMAN,tr|D6RIT2|D6RIT2_HUMAN,tr|D6R9T0|D6R9T0_HUMAN,tr|D6RIU0|D6RIU0_HUMAN,tr|D6RAM1|D6RAM1_HUMAN,tr|D6RBM0|D6RBM0_HUMAN,tr|G8JLB6|G8JLB6_HUMAN,tr|D6RDL0|D6RDL0_HUMAN,tr|D6RDU3|D6RDU3_HUMAN,tr|E7EN40|E7EN40_HUMAN" 15 1763.8101 1.6 34497 19483 2 1763.810079 882.9123 Heterogeneous nuclear ribonucleoprotein H OS=Homo sapiens OX=9606 GN=HNRNPH1 PE=1 SV=4 3.83 3251 - 2.46E+06 - - - -0.0352 - 4.456 0.716 - 2195.2 1 1 0 -0.0001 16 0 0 0 5.46E+07 3.41E+07 - - - 8.003 1 221125_WJC_METTL3_EV_vs_WT_F03.19485.19485.2 5.17E-12 16/26 R.C[160.03]ESGFIEELPEETR[166.11].S "sp|Q9BV68|RN126_HUMAN,tr|U3KQF4|U3KQF4_HUMAN,tr|K7EIY6|K7EIY6_HUMAN" 3 1704.754 2.13 34499 19485 2 1704.751586 853.3843 E3 ubiquitin-protein ligase RNF126 OS=Homo sapiens OX=9606 GN=RNF126 PE=1 SV=2 3.98 3251.3 - 1.59E+06 - - - -1.4372 - 3.081 0.689 - 951.2 1 2 0 -0.0024 14 0 0 0 4.40E+07 2.06E+07 - - - 6.953 1 221125_WJC_METTL3_EV_vs_WT_F03.19486.19486.2 1.38E-08 15/26 R.YGPLSGVNVVYDQR.T sp|Q13595|TRA2A_HUMAN 1 1565.7838 1.74 34500 19486 2 1565.779264 783.8992 Transformer-2 protein homolog alpha OS=Homo sapiens OX=9606 GN=TRA2A PE=1 SV=1 5.83 3251.4 - 1.26E+06 - - - -2.9014 - 2.668 0.645 - 773.4 1 2 0 -0.0045 14 0 0 0 6.46E+07 3.71E+07 - - - 6.2661 1 221125_WJC_METTL3_EV_vs_WT_F03.19490.19490.2 8.87E-10 17/32 K.NGVQAMVEFDSVQSAQR.A "sp|P14866|HNRPL_HUMAN,tr|M0QYL7|M0QYL7_HUMAN,tr|B4DVF8|B4DVF8_HUMAN,tr|M0R1W6|M0R1W6_HUMAN,tr|A0A3B3ITJ4|A0A3B3ITJ4_HUMAN,tr|M0QXS5|M0QXS5_HUMAN" 6 1864.8738 1.6 34503 19490 2 1864.866682 933.4442 Heterogeneous nuclear ribonucleoprotein L OS=Homo sapiens OX=9606 GN=HNRNPL PE=1 SV=2 4.37 3251.9 - 1.97E+06 - - - -3.796 - 3.718 0.676 - 1020.3 1 2 0 -0.0071 17 0 0 0 3.55E+07 2.23E+07 - - - 7.2602 1 221125_WJC_METTL3_EV_vs_WT_F03.19492.19492.3 1.50E-05 15/64 K.VAGHSLGYGFVNYVTAK[136.11].D "sp|Q15717|ELAV1_HUMAN,tr|M0QZR9|M0QZR9_HUMAN" 2 1789.9243 1.36 34505 19492 3 1789.921253 597.6487 ELAV-like protein 1 OS=Homo sapiens OX=9606 GN=ELAVL1 PE=1 SV=2 8.48 3252.1 - 5.91E+06 - - - -1.6855 - 2.796 0.474 - 308.2 1 2 0 -0.003 17 0 0 0 1.78E+08 1.31E+08 - - - 6.4213 1 221125_WJC_METTL3_EV_vs_WT_F03.19495.19495.3 2.30E-07 16/64 K.TDMDNQIVVSDYAQMDR[166.11].V sp|P50991|TCPD_HUMAN 1 2009.8698 0.13 34508 19495 3 2009.86413 670.9639 T-complex protein 1 subunit delta OS=Homo sapiens OX=9606 GN=CCT4 PE=1 SV=4 3.77 3252.5 - 1.98E+06 - - - -2.8266 - 3.328 0.629 - 347.5 1 2 0 -0.0057 17 0 0 0 2.58E+06 1.95E+07 - - - 8.5887 1 221125_WJC_METTL3_EV_vs_WT_F03.19496.19496.3 2.86E-09 25/64 R.VVVEPVGPVGFKPETFR.K "sp|Q9BZE1|RM37_HUMAN,tr|A6NHR2|A6NHR2_HUMAN" 2 1856.0196 1.25 34509 19496 3 1856.019826 619.6805 "39S ribosomal protein L37, mitochondrial OS=Homo sapiens OX=9606 GN=MRPL37 PE=1 SV=2" 6.11 3252.6 - 1.78E+06 - - - 0.111 - 3.87 0.603 - 887.8 1 2 0 0.0002 17 0 0 0 1.18E+07 9.49E+06 - - - 8.6815 1 221125_WJC_METTL3_EV_vs_WT_F03.19498.19498.3 1.46E-05 18/52 R.C[160.03]ESGFIEELPEETR.S "sp|Q9BV68|RN126_HUMAN,tr|U3KQF4|U3KQF4_HUMAN,tr|K7EIY6|K7EIY6_HUMAN" 3 1694.7458 1.22 34511 19498 3 1694.743955 565.9225 E3 ubiquitin-protein ligase RNF126 OS=Homo sapiens OX=9606 GN=RNF126 PE=1 SV=2 3.98 3252.9 - 981838 - - - -1.0686 - 2.994 0.542 - 423.5 1 2 0 -0.0018 14 0 0 0 9.44E+06 7.74E+06 - - - 7.4965 0.9436 221125_WJC_METTL3_EV_vs_WT_F03.19499.19499.3 0.0918 13/52 R.WNHVWVGTETGILK.G "sp|Q6RFH5|WDR74_HUMAN,tr|F5GYL6|F5GYL6_HUMAN" 2 1638.8518 1.59 34512 19499 3 1638.851853 547.2912 WD repeat-containing protein 74 OS=Homo sapiens OX=9606 GN=WDR74 PE=1 SV=1 6.75 3253 - 970885 - - - 0.0159 - 1.413 0.119 - 70.6 1 2 0 0 14 0 0 0 7.18E+06 4.52E+06 - - - 0.7855 1 221125_WJC_METTL3_EV_vs_WT_F03.19500.19500.2 1.06E-11 15/32 K.TDMDNQIVVSDYAQMDR.V sp|P50991|TCPD_HUMAN 1 1999.8615 0.19 34513 19500 2 1999.858813 1000.938 T-complex protein 1 subunit delta OS=Homo sapiens OX=9606 GN=CCT4 PE=1 SV=4 3.77 3253.1 - 794196 - - - -1.3641 - 3.446 0.732 - 601.4 1 2 0 -0.0027 17 0 0 0 5.47E+06 2.90E+07 - - - 7.4884 0.9654 221125_WJC_METTL3_EV_vs_WT_F03.19501.19501.3 0.0171 Dec-36 K.DVWQVIVKPR.G "sp|O14654|IRS4_HUMAN,tr|A0A804CF45|A0A804CF45_HUMAN" 2 1238.7135 0.64 34514 19501 3 1238.710539 413.9118 Insulin receptor substrate 4 OS=Homo sapiens OX=9606 GN=IRS4 PE=1 SV=1 8.75 3253.2 - 757265 - - - -2.4243 - 1.93 0.101 - 194.7 1 2 0 -0.003 10 0 0 0 4.35E+07 6.81E+07 - - - 1.5855 0.9912 221125_WJC_METTL3_EV_vs_WT_F03.19505.19505.3 0.0834 Nov-36 K.DVWQVIVK[136.11]PR[166.11].G "sp|O14654|IRS4_HUMAN,tr|A0A804CF45|A0A804CF45_HUMAN" 2 1256.736 0.64 34516 19505 3 1256.733627 419.9193 Insulin receptor substrate 4 OS=Homo sapiens OX=9606 GN=IRS4 PE=1 SV=1 8.75 3253.7 - 3.85E+06 - - - -1.8978 - 1.742 0.183 - 135.5 1 2 0 -0.0024 10 0 0 0 4.35E+07 6.81E+07 - - - 2.2006 1 221125_WJC_METTL3_EV_vs_WT_F03.19506.19506.2 1.81E-05 16/30 R.GLPLTGEYYVENADGK[136.11].V "sp|Q6W2J9|BCOR_HUMAN,tr|H7BZ37|H7BZ37_HUMAN,tr|H7C2V9|H7C2V9_HUMAN,tr|H7C231|H7C231_HUMAN" 4 1732.8399 1.84 34517 19506 2 1732.840749 867.4272 BCL-6 corepressor OS=Homo sapiens OX=9606 GN=BCOR PE=1 SV=1 4.14 3253.8 - 2.24E+06 - - - 0.4721 - 2.869 0.592 - 728.9 1 2 0 0.0008 16 0 0 0 5.20E+07 2.83E+07 - - - 6.0045 0.9998 221125_WJC_METTL3_EV_vs_WT_F03.19507.19507.2 8.90E-05 20-Dec R.ETLFNTLANNR.E "sp|P35658|NU214_HUMAN,tr|A0A0A0MSW3|A0A0A0MSW3_HUMAN,tr|A0A494C1F2|A0A494C1F2_HUMAN" 3 1291.6521 2.97 34518 19507 2 1291.650981 646.8333 Nuclear pore complex protein Nup214 OS=Homo sapiens OX=9606 GN=NUP214 PE=1 SV=2 6.1 3253.8 - 1.42E+07 - - - -0.8385 - 2.179 0.428 - 686.8 1 2 0 -0.0011 11 0 0 0 2.28E+08 7.66E+07 - - - 4.3089 0.9988 221125_WJC_METTL3_EV_vs_WT_F03.19511.19511.3 2.70E-10 19/60 R.PSGEAFVELESEDEVK.L "sp|P31943|HNRH1_HUMAN,tr|E7EQJ0|E7EQJ0_HUMAN,tr|D6RIH9|D6RIH9_HUMAN,tr|D6RJ04|D6RJ04_HUMAN,tr|D6RFM3|D6RFM3_HUMAN,tr|E9PCY7|E9PCY7_HUMAN,tr|D6RIT2|D6RIT2_HUMAN,tr|D6R9T0|D6R9T0_HUMAN,tr|D6RIU0|D6RIU0_HUMAN,tr|D6RAM1|D6RAM1_HUMAN,tr|D6RBM0|D6RBM0_HUMAN,tr|G8JLB6|G8JLB6_HUMAN,tr|D6RDL0|D6RDL0_HUMAN,tr|D6RDU3|D6RDU3_HUMAN,tr|E7EN40|E7EN40_HUMAN" 15 1763.8101 1.25 34522 19511 3 1763.807902 588.944 Heterogeneous nuclear ribonucleoprotein H OS=Homo sapiens OX=9606 GN=HNRNPH1 PE=1 SV=4 3.83 3254.1 - 2.57E+06 - - - -1.2694 - 3.28 0.6 - 647.1 1 1 0 -0.0022 16 0 0 0 2.64E+07 2.11E+07 - - - 8.2766 0.9937 221125_WJC_METTL3_EV_vs_WT_F03.19513.19513.2 3.83E-07 26-Dec L.GIYPAVDPLDSTSR.L "sp|P06576|ATPB_HUMAN,tr|H0YH81|H0YH81_HUMAN" 2 1489.7413 45.23 34524 19513 2 1489.74176 745.8779 "ATP synthase subunit beta, mitochondrial OS=Homo sapiens OX=9606 GN=ATP5F1B PE=1 SV=3" 4.21 3254.4 - 1.50E+06 - - - 0.3269 - 2.123 0.58 - 323.3 1 1 0 0.0005 14 0 0 0 2.22E+07 4.90E+05 - - - 5.2139 1 221125_WJC_METTL3_EV_vs_WT_F03.19514.19514.2 1.67E-05 20/30 K.YPIEHGIITNWDDMEK[136.11].L "sp|P68133|ACTS_HUMAN,sp|P62736|ACTA_HUMAN,sp|P68032|ACTC_HUMAN,sp|P63267|ACTH_HUMAN,tr|B8ZZJ2|B8ZZJ2_HUMAN,tr|F6QUT6|F6QUT6_HUMAN,tr|F6UVQ4|F6UVQ4_HUMAN,tr|F8WB63|F8WB63_HUMAN,tr|A0A804HKV3|A0A804HKV3_HUMAN,tr|C9JFL5|C9JFL5_HUMAN,tr|A6NL76|A6NL76_HUMAN" 11 1967.9179 0.79 34525 19514 2 1967.915321 984.9662 "Actin, alpha skeletal muscle OS=Homo sapiens OX=9606 GN=ACTA1 PE=1 SV=1" 4.31 3254.5 - 1.19E+06 - - - -1.2922 - 3.569 0.565 - 972.2 1 2 0 -0.0025 16 0 0 0 2.07E+07 2.61E+07 - - - 6.3413 0.9999 221125_WJC_METTL3_EV_vs_WT_F03.19515.19515.3 0.0217 18/40 R.TEVVSLLLDRK.A "sp|O75179|ANR17_HUMAN,tr|H0YM23|H0YM23_HUMAN,tr|H0YLQ3|H0YLQ3_HUMAN" 3 1271.7449 2.11 34526 19515 3 1271.742333 424.9222 Ankyrin repeat domain-containing protein 17 OS=Homo sapiens OX=9606 GN=ANKRD17 PE=1 SV=3 5.74 3254.6 - 1.00E+06 - - - -2.0201 - 2.888 0.417 - 607.6 1 2 0 -0.0026 11 0 0 0 1.07E+07 5.07E+06 - - - 6.2013 1 221125_WJC_METTL3_EV_vs_WT_F03.19516.19516.3 6.88E-06 16/52 R.LQQALSDAENEIMR[166.11].L "sp|Q15643|TRIPB_HUMAN,tr|H0YJ97|H0YJ97_HUMAN" 2 1626.7911 1.14 34527 19516 3 1626.789519 543.271 Thyroid receptor-interacting protein 11 OS=Homo sapiens OX=9606 GN=TRIP11 PE=1 SV=3 4.14 3254.7 - 905593 - - - -0.9657 - 3.273 0.518 - 497.2 1 2 0 -0.0016 14 0 0 0 3.55E+07 3.12E+07 - - - 7.4658 0.797 221125_WJC_METTL3_EV_vs_WT_F03.19519.19519.3 0.616 Aug-40 K.NSLESYAFNMK.A "sp|P11142|HSP7C_HUMAN,tr|E9PNE6|E9PNE6_HUMAN,tr|A8K7Q2|A8K7Q2_HUMAN,tr|E9PKE3|E9PKE3_HUMAN,tr|E9PM13|E9PM13_HUMAN,tr|E9PS65|E9PS65_HUMAN" 6 1302.5914 0.11 34530 19519 3 1302.59025 435.2044 Heat shock cognate 71 kDa protein OS=Homo sapiens OX=9606 GN=HSPA8 PE=1 SV=1 6 3255.1 - 468868 - - - -0.912 - 1.51 0.026 - 74.2 1 2 0 -0.0012 11 0 0 0 5.52E+06 4.93E+07 - - - 0.0003 0.9999 221125_WJC_METTL3_EV_vs_WT_F03.19523.19523.2 1.61E-05 24-Dec R.TLSFGSDLNYATR.E sp|Q14152|EIF3A_HUMAN 1 1443.6994 1.41 34532 19523 2 1443.69807 722.857 Eukaryotic translation initiation factor 3 subunit A OS=Homo sapiens OX=9606 GN=EIF3A PE=1 SV=1 5.5 3255.6 - 7.86E+06 - - - -0.9268 - 2.344 0.581 - 378 1 2 0 -0.0013 13 0 0 0 8.84E+07 6.28E+07 - - - 5.5182 1 221125_WJC_METTL3_EV_vs_WT_F03.19525.19525.2 2.60E-06 15/26 R.LQQALSDAENEIMR.L "sp|Q15643|TRIPB_HUMAN,tr|H0YJ97|H0YJ97_HUMAN" 2 1616.7828 1.19 34534 19525 2 1616.778695 809.3987 Thyroid receptor-interacting protein 11 OS=Homo sapiens OX=9606 GN=TRIP11 PE=1 SV=3 4.14 3255.7 - 4.51E+06 - - - -2.5514 - 3.299 0.641 - 975 1 2 0 -0.0041 14 0 0 0 8.85E+07 7.42E+07 - - - 6.7695 1 221125_WJC_METTL3_EV_vs_WT_F03.19526.19526.2 0.000161 15/26 R.LQQALSDAENEIMR[166.11].L "sp|Q15643|TRIPB_HUMAN,tr|H0YJ97|H0YJ97_HUMAN" 2 1626.7911 1.19 34535 19526 2 1626.790662 814.4028 Thyroid receptor-interacting protein 11 OS=Homo sapiens OX=9606 GN=TRIP11 PE=1 SV=3 4.14 3255.7 - 3.15E+06 - - - -0.2631 - 3.204 0.535 - 925.6 1 2 0 -0.0004 14 0 0 0 8.85E+07 7.42E+07 - - - 5.9144 1 221125_WJC_METTL3_EV_vs_WT_F03.19527.19527.3 1.91E-06 21/60 R.VQLFEDPTVDKEVEIR.K sp|P51948|MAT1_HUMAN 1 1915.9891 1.42 34536 19527 3 1915.987868 639.6703 CDK-activating kinase assembly factor MAT1 OS=Homo sapiens OX=9606 GN=MNAT1 PE=1 SV=1 4.18 3255.8 - 2.55E+06 - - - -0.6472 - 3.89 0.643 - 674.7 1 2 1 -0.0012 16 0 0 0 4.81E+07 3.38E+07 - - - 9.194 1 221125_WJC_METTL3_EV_vs_WT_F03.19528.19528.3 1.14E-08 15/52 R.LQQALSDAENEIMR.L "sp|Q15643|TRIPB_HUMAN,tr|H0YJ97|H0YJ97_HUMAN" 2 1616.7828 1.14 34537 19528 3 1616.780427 539.9349 Thyroid receptor-interacting protein 11 OS=Homo sapiens OX=9606 GN=TRIP11 PE=1 SV=3 4.14 3255.9 - 2.05E+06 - - - -1.4801 - 3.171 0.582 - 473.7 1 2 0 -0.0024 14 0 0 0 3.55E+07 3.12E+07 - - - 8.095 1 221125_WJC_METTL3_EV_vs_WT_F03.19530.19530.2 4.30E-07 16/30 K.YPIEHGIITNWDDMEK.L "sp|P68133|ACTS_HUMAN,sp|P62736|ACTA_HUMAN,sp|P68032|ACTC_HUMAN,sp|P63267|ACTH_HUMAN,tr|B8ZZJ2|B8ZZJ2_HUMAN,tr|F6QUT6|F6QUT6_HUMAN,tr|F6UVQ4|F6UVQ4_HUMAN,tr|F8WB63|F8WB63_HUMAN,tr|A0A804HKV3|A0A804HKV3_HUMAN,tr|C9JFL5|C9JFL5_HUMAN,tr|A6NL76|A6NL76_HUMAN" 11 1959.9037 0.79 34539 19530 2 1959.90426 980.9591 "Actin, alpha skeletal muscle OS=Homo sapiens OX=9606 GN=ACTA1 PE=1 SV=1" 4.31 3256.1 - 1.56E+06 - - - 0.3041 - 3.435 0.612 - 625.1 1 2 0 0.0006 16 0 0 0 2.07E+07 2.61E+07 - - - 6.5949 1 221125_WJC_METTL3_EV_vs_WT_F03.19531.19531.2 2.24E-10 18/32 H.SLGGGTGSGMGTLLISK.L "sp|P04350|TBB4A_HUMAN,sp|Q9BVA1|TBB2B_HUMAN,sp|A6NNZ2|TBB8B_HUMAN,sp|P07437|TBB5_HUMAN,sp|Q13509|TBB3_HUMAN,sp|Q13885|TBB2A_HUMAN,sp|P68371|TBB4B_HUMAN,sp|Q9BUF5|TBB6_HUMAN,sp|Q3ZCM7|TBB8_HUMAN,tr|A0A0B4J269|A0A0B4J269_HUMAN,tr|Q5ST81|Q5ST81_HUMAN,tr|Q5JP53|Q5JP53_HUMAN,tr|M0R042|M0R042_HUMAN,tr|K7ESM5|K7ESM5_HUMAN,tr|M0QYM7|M0QYM7_HUMAN,tr|A0A075B736|A0A075B736_HUMAN,tr|K7ES63|K7ES63_HUMAN,tr|G3V2A3|G3V2A3_HUMAN,tr|Q5SQY0|Q5SQY0_HUMAN" 19 1534.8025 0.54 34540 19531 2 1534.802561 768.4085 Tubulin beta-4A chain OS=Homo sapiens OX=9606 GN=TUBB4A PE=1 SV=2 8.47 3256.2 - 1.19E+06 - - - 0.0443 - 3.249 0.603 - 764.5 1 1 0 0.0001 17 0 0 0 4.49E+07 8.39E+07 - - - 6.3918 0.9999 221125_WJC_METTL3_EV_vs_WT_F03.19538.19538.3 0.00105 Dec-64 R.TLSADASVNTLPVVVSR[166.11].E "sp|Q92615|LAR4B_HUMAN,tr|H0Y641|H0Y641_HUMAN,tr|H0Y4V9|H0Y4V9_HUMAN" 3 1737.95 1.16 34545 19538 3 1737.948011 580.324 La-related protein 4B OS=Homo sapiens OX=9606 GN=LARP4B PE=1 SV=3 5.5 3257.1 - 1.34E+07 - - - -1.164 - 2.307 0.449 - 106.9 1 2 0 -0.002 17 0 0 0 1.84E+08 1.59E+08 - - - 5.6572 0.9999 221125_WJC_METTL3_EV_vs_WT_F03.19539.19539.2 4.45E-05 13/34 K.VGINYQPPTVVPGGDLAK.V "sp|Q9NY65|TBA8_HUMAN,sp|Q6PEY2|TBA3E_HUMAN,sp|P0DPH7|TBA3C_HUMAN,sp|Q71U36|TBA1A_HUMAN,sp|P0DPH8|TBA3D_HUMAN,sp|P68366|TBA4A_HUMAN,sp|P68363|TBA1B_HUMAN,sp|Q9BQE3|TBA1C_HUMAN,tr|A0A1W2PQM2|A0A1W2PQM2_HUMAN,tr|F5H5D3|F5H5D3_HUMAN,tr|C9J2C0|C9J2C0_HUMAN,tr|V9GZ17|V9GZ17_HUMAN,tr|A0A7P0T945|A0A7P0T945_HUMAN" 13 1823.9781 0.62 34546 19539 2 1823.977593 912.9964 Tubulin alpha-8 chain OS=Homo sapiens OX=9606 GN=TUBA8 PE=1 SV=1 5.81 3257.2 - 5.64E+06 - - - -0.3048 - 1.926 0.536 - 307.1 1 2 0 -0.0006 18 0 0 0 3.61E+08 5.79E+08 - - - 4.6112 1 221125_WJC_METTL3_EV_vs_WT_F03.19540.19540.2 7.49E-07 15/30 K.IQEGVFDINNEANGIK.L sp|P61019|RAB2A_HUMAN 1 1759.8741 1.21 34547 19540 2 1759.872037 880.9443 Ras-related protein Rab-2A OS=Homo sapiens OX=9606 GN=RAB2A PE=1 SV=1 4.14 3257.2 - 4.60E+06 - - - -1.1597 - 3.378 0.605 - 731.7 1 2 0 -0.002 16 0 0 0 6.70E+07 5.54E+07 - - - 6.5016 0.9992 221125_WJC_METTL3_EV_vs_WT_F03.19543.19543.3 0.0318 14/48 K.LK[136.11]EVFSMAGVVVR[166.11].A "sp|P52272|HNRPM_HUMAN,tr|M0R019|M0R019_HUMAN,tr|M0R0N3|M0R0N3_HUMAN,tr|A0A087X0X3|A0A087X0X3_HUMAN,tr|M0QZM1|M0QZM1_HUMAN,tr|M0QYQ7|M0QYQ7_HUMAN,tr|M0R2T0|M0R2T0_HUMAN" 7 1451.8289 1.42 34550 19543 3 1451.827752 484.9503 Heterogeneous nuclear ribonucleoprotein M OS=Homo sapiens OX=9606 GN=HNRNPM PE=1 SV=3 8.75 3257.4 - 3.04E+06 - - - -0.8086 - 2.631 0.318 - 296.6 1 2 1 -0.0012 13 0 0 0 1.82E+08 1.28E+08 - - - 4.7079 1 221125_WJC_METTL3_EV_vs_WT_F03.19545.19545.2 2.16E-09 14/30 R.TFNTSTGGLLLPSDTK.R "sp|P12956|XRCC6_HUMAN,tr|B1AHC9|B1AHC9_HUMAN" 2 1650.8465 5.34 34552 19545 2 1650.843898 826.4305 X-ray repair cross-complementing protein 6 OS=Homo sapiens OX=9606 GN=XRCC6 PE=1 SV=2 5.5 3257.5 - 2.12E+06 - - - -1.5562 - 3.273 0.649 - 362.2 1 2 0 -0.0026 16 0 0 0 3.96E+07 7.41E+06 - - - 6.7488 0.9941 221125_WJC_METTL3_EV_vs_WT_F03.19546.19546.3 0.00699 Nov-36 R.EK[136.11]DLEDLFYK[136.11].Y "sp|Q13242|SRSF9_HUMAN,tr|H0YIB4|H0YIB4_HUMAN,tr|S4R3G0|S4R3G0_HUMAN" 3 1314.6678 1.39 34553 19546 3 1314.669124 439.2299 Serine\arginine-rich splicing factor 9 OS=Homo sapiens OX=9606 GN=SRSF9 PE=1 SV=1 4.32 3257.6 - 1.44E+06 - - - 0.9812 - 1.818 0.261 - 185.4 1 2 1 0.0013 10 0 0 0 3.31E+07 2.38E+07 - - - 3.1952 0.9998 221125_WJC_METTL3_EV_vs_WT_F03.19547.19547.3 0.00219 14/48 K.NLHGDGIALWYTR[166.11].D "sp|Q12907|LMAN2_HUMAN,tr|D6RBV2|D6RBV2_HUMAN,tr|D6RDX1|D6RDX1_HUMAN,tr|D6RBH1|D6RBH1_HUMAN,tr|D6RIU4|D6RIU4_HUMAN" 5 1524.7713 0.99 34554 19547 3 1524.770077 509.2644 Vesicular integral-membrane protein VIP36 OS=Homo sapiens OX=9606 GN=LMAN2 PE=1 SV=1 6.74 3257.8 - 1.43E+06 - - - -0.7903 - 2.675 0.323 - 314.1 1 2 0 -0.0012 13 0 0 0 1.56E+07 1.57E+07 - - - 4.8086 0.9996 221125_WJC_METTL3_EV_vs_WT_F03.19548.19548.3 0.000484 Nov-36 R.EKDLEDLFYK.Y "sp|Q13242|SRSF9_HUMAN,tr|H0YIB4|H0YIB4_HUMAN,tr|S4R3G0|S4R3G0_HUMAN" 3 1298.6394 1.33 34555 19548 3 1298.638651 433.8871 Serine\arginine-rich splicing factor 9 OS=Homo sapiens OX=9606 GN=SRSF9 PE=1 SV=1 4.32 3257.9 - 1.16E+06 - - - -0.6029 - 2.136 0.415 - 225.4 1 2 1 -0.0008 10 0 0 0 3.32E+07 2.50E+07 - - - 5.383 1 221125_WJC_METTL3_EV_vs_WT_F03.19549.19549.3 1.92E-07 19/64 K.HLVVPGDTITTDTGFMR.G "sp|Q13868|EXOS2_HUMAN,tr|A3KFL1|A3KFL1_HUMAN,tr|A3KFL2|A3KFL2_HUMAN,tr|A3KFL5|A3KFL5_HUMAN" 4 1858.9247 1.41 34556 19549 3 1858.9268 620.6489 Exosome complex component RRP4 OS=Homo sapiens OX=9606 GN=EXOSC2 PE=1 SV=2 5.21 3258 - 1.05E+06 - - - 1.1114 - 2.827 0.512 - 497.5 1 2 0 0.0021 17 0 0 0 1.34E+07 9.48E+06 - - - 6.8731 0.9999 221125_WJC_METTL3_EV_vs_WT_F03.19550.19550.3 4.62E-05 15/44 R.ASEAVLWEALRK.M "sp|Q9Y5V3|MAGD1_HUMAN,sp|Q96JG8|MAGD4_HUMAN" 2 1371.7511 1.04 34557 19550 3 1371.754195 458.2576 Melanoma-associated antigen D1 OS=Homo sapiens OX=9606 GN=MAGED1 PE=1 SV=3 6.19 3258.1 - 576697 - - - 2.2927 - 2.851 0.383 - 420.3 1 2 0 0.0031 12 0 0 0 7.04E+06 6.75E+06 - - - 5.7132 0.9996 221125_WJC_METTL3_EV_vs_WT_F03.19551.19551.2 0.00785 22-Sep K.QSLQVIESAMER.D "sp|Q16740|CLPP_HUMAN,tr|M0R208|M0R208_HUMAN" 2 1389.6922 1.05 34558 19551 2 1389.692685 695.8534 "ATP-dependent Clp protease proteolytic subunit, mitochondrial OS=Homo sapiens OX=9606 GN=CLPP PE=1 SV=1" 4.53 3258.2 - 462565 - - - 0.3389 - 1.882 0.352 - 237.7 1 2 0 0.0005 12 0 0 0 7.72E+06 7.32E+06 - - - 3.3045 0.9997 221125_WJC_METTL3_EV_vs_WT_F03.19552.19552.2 0.00127 18-Jul R.HYPDIFEEC[160.03]G.- sp|P0C7X2|ZN688_HUMAN 1 1265.5023 - 34559 19552 2 1265.501563 633.7584 Zinc finger protein 688 OS=Homo sapiens OX=9606 GN=ZNF688 PE=1 SV=1 4.13 3258.4 - 388731 - - - -0.5737 - 1.428 0.465 - 136.5 1 2 0 -0.0007 10 0 0 0 - - - - - 3.4697 0.9998 221125_WJC_METTL3_EV_vs_WT_F03.19554.19554.2 0.000123 13/30 R.AITIAGVPQSVTEC[160.03]VK[136.11].Q sp|Q15365|PCBP1_HUMAN 1 1679.9008 0.48 34560 19554 2 1679.900895 840.9577 Poly(rC)-binding protein 1 OS=Homo sapiens OX=9606 GN=PCBP1 PE=1 SV=2 6.04 3258.6 - 980257 - - - 0.0821 - 2.106 0.436 - 358.4 1 2 0 0.0001 16 0 0 0 8.78E+06 1.85E+07 - - - 4.0924 0.9999 221125_WJC_METTL3_EV_vs_WT_F03.19556.19556.3 3.51E-05 Dec-60 K.YPIEHGIITNWDDMEK.L "sp|P68133|ACTS_HUMAN,sp|P62736|ACTA_HUMAN,sp|P68032|ACTC_HUMAN,sp|P63267|ACTH_HUMAN,tr|B8ZZJ2|B8ZZJ2_HUMAN,tr|F6QUT6|F6QUT6_HUMAN,tr|F6UVQ4|F6UVQ4_HUMAN,tr|F8WB63|F8WB63_HUMAN,tr|A0A804HKV3|A0A804HKV3_HUMAN,tr|C9JFL5|C9JFL5_HUMAN,tr|A6NL76|A6NL76_HUMAN" 11 1959.9037 1.1 34561 19556 3 1959.903141 654.3085 "Actin, alpha skeletal muscle OS=Homo sapiens OX=9606 GN=ACTA1 PE=1 SV=1" 4.31 3258.8 - 3.48E+07 - - - -0.2668 - 2.146 0.481 - 125 1 2 0 -0.0005 16 0 0 0 5.84E+08 5.30E+08 - - - 5.8618 1 221125_WJC_METTL3_EV_vs_WT_F03.19557.19557.2 1.22E-10 14/32 H.SLGGGTGSGMGTLLISK[136.11].L "sp|P04350|TBB4A_HUMAN,sp|Q9BVA1|TBB2B_HUMAN,sp|A6NNZ2|TBB8B_HUMAN,sp|P07437|TBB5_HUMAN,sp|Q13509|TBB3_HUMAN,sp|Q13885|TBB2A_HUMAN,sp|P68371|TBB4B_HUMAN,sp|Q9BUF5|TBB6_HUMAN,sp|Q3ZCM7|TBB8_HUMAN,tr|A0A0B4J269|A0A0B4J269_HUMAN,tr|Q5ST81|Q5ST81_HUMAN,tr|Q5JP53|Q5JP53_HUMAN,tr|M0R042|M0R042_HUMAN,tr|K7ESM5|K7ESM5_HUMAN,tr|M0QYM7|M0QYM7_HUMAN,tr|A0A075B736|A0A075B736_HUMAN,tr|K7ES63|K7ES63_HUMAN,tr|G3V2A3|G3V2A3_HUMAN,tr|Q5SQY0|Q5SQY0_HUMAN" 19 1542.8167 0.53 34562 19557 2 1542.815497 772.4156 Tubulin beta-4A chain OS=Homo sapiens OX=9606 GN=TUBB4A PE=1 SV=2 8.47 3258.8 - 6.15E+06 - - - -0.7752 - 2.8 0.619 - 416 1 1 0 -0.0012 17 0 0 0 4.49E+07 8.49E+07 - - - 6.1439 0.9999 221125_WJC_METTL3_EV_vs_WT_F03.19558.19558.3 8.82E-06 15/48 K.LKEVFSMAGVVVR.A "sp|P52272|HNRPM_HUMAN,tr|M0R019|M0R019_HUMAN,tr|M0R0N3|M0R0N3_HUMAN,tr|A0A087X0X3|A0A087X0X3_HUMAN,tr|M0QZM1|M0QZM1_HUMAN,tr|M0QYQ7|M0QYQ7_HUMAN,tr|M0R2T0|M0R2T0_HUMAN" 7 1433.8065 1.42 34563 19558 3 1433.805075 478.9428 Heterogeneous nuclear ribonucleoprotein M OS=Homo sapiens OX=9606 GN=HNRNPM PE=1 SV=3 8.75 3258.9 - 7.51E+06 - - - -0.9632 - 2.775 0.518 - 334.6 1 2 1 -0.0014 13 0 0 0 1.83E+08 1.29E+08 - - - 7.0821 1 221125_WJC_METTL3_EV_vs_WT_F03.19559.19559.3 7.85E-13 19/68 K.LFTAHNNMTNYATVWASK.T sp|Q08211|DHX9_HUMAN 1 2067.9836 1.35 34564 19559 3 2067.98436 690.3352 ATP-dependent RNA helicase A OS=Homo sapiens OX=9606 GN=DHX9 PE=1 SV=4 8.6 3258.9 - 4.27E+06 - - - 0.3453 - 3.038 0.689 - 527 1 2 0 0.0007 18 0 0 0 4.07E+07 3.02E+07 - - - 8.9885 1 221125_WJC_METTL3_EV_vs_WT_F03.19560.19560.3 1.10E-09 18/68 K.LFTAHNNMTNYATVWASK[136.11].T sp|Q08211|DHX9_HUMAN 1 2075.9978 1.36 34565 19560 3 2075.995635 693.0066 ATP-dependent RNA helicase A OS=Homo sapiens OX=9606 GN=DHX9 PE=1 SV=4 8.6 3259 - 3.69E+06 - - - -1.065 - 3.032 0.613 - 485.4 1 2 0 -0.0022 18 0 0 0 4.12E+07 3.02E+07 - - - 8.1358 0.9999 221125_WJC_METTL3_EV_vs_WT_F03.19561.19561.3 3.94E-06 14/48 K.IFVEFSIASETHK[136.11].A "sp|Q9UHX1|PUF60_HUMAN,tr|A0A0J9YYL3|A0A0J9YYL3_HUMAN,tr|A0A0J9YXX5|A0A0J9YXX5_HUMAN,tr|A0A0J9YXJ8|A0A0J9YXJ8_HUMAN,tr|A0A0J9YVP6|A0A0J9YVP6_HUMAN" 5 1514.786 1.96 34566 19561 3 1514.784492 505.936 Poly(U)-binding-splicing factor PUF60 OS=Homo sapiens OX=9606 GN=PUF60 PE=1 SV=1 5.4 3259 - 3.51E+06 - - - -1.0252 - 2.211 0.424 - 198.2 1 2 0 -0.0016 13 0 0 0 5.49E+07 2.79E+07 - - - 5.418 1 221125_WJC_METTL3_EV_vs_WT_F03.19562.19562.3 0.000107 14/60 K.IQEGVFDINNEANGIK[136.11].L sp|P61019|RAB2A_HUMAN 1 1767.8883 0.89 34567 19562 3 1767.889025 590.3034 Ras-related protein Rab-2A OS=Homo sapiens OX=9606 GN=RAB2A PE=1 SV=1 4.14 3259.1 - 1.64E+06 - - - 0.4225 - 2.348 0.478 - 199.3 1 2 0 0.0007 16 0 0 0 1.58E+07 1.78E+07 - - - 6.0591 1 221125_WJC_METTL3_EV_vs_WT_F03.19564.19564.2 1.66E-08 14/28 K.GISC[160.03]MNTTLSESPFK[136.11].C sp|Q15181|IPYR_HUMAN 1 1678.7786 0.57 34569 19564 2 1678.775008 840.3966 Inorganic pyrophosphatase OS=Homo sapiens OX=9606 GN=PPA1 PE=1 SV=2 5.99 3259.3 - 1.25E+06 - - - -2.1355 - 2.753 0.579 - 716.7 1 2 0 -0.0036 15 0 0 0 8.01E+06 1.42E+07 - - - 5.8061 0.9933 221125_WJC_METTL3_EV_vs_WT_F03.19565.19565.2 3.66E-05 14/24 K.LKEVFSMAGVVVR.A "sp|P52272|HNRPM_HUMAN,tr|M0R019|M0R019_HUMAN,tr|M0R0N3|M0R0N3_HUMAN,tr|A0A087X0X3|A0A087X0X3_HUMAN,tr|M0QZM1|M0QZM1_HUMAN,tr|M0QYQ7|M0QYQ7_HUMAN,tr|M0R2T0|M0R2T0_HUMAN" 7 1433.8065 1.51 34570 19565 2 1433.809772 717.9105 Heterogeneous nuclear ribonucleoprotein M OS=Homo sapiens OX=9606 GN=HNRNPM PE=1 SV=3 8.75 3259.4 - 796477 - - - 2.3127 - 2.632 0.337 - 590.8 1 2 1 0.0033 13 0 0 0 2.25E+07 1.49E+07 - - - 4.0128 1 221125_WJC_METTL3_EV_vs_WT_F03.19571.19571.3 1.33E-08 15/64 R.TLSADASVNTLPVVVSR.E "sp|Q92615|LAR4B_HUMAN,tr|H0Y641|H0Y641_HUMAN,tr|H0Y4V9|H0Y4V9_HUMAN" 3 1727.9418 1.16 34574 19571 3 1727.942062 576.9879 La-related protein 4B OS=Homo sapiens OX=9606 GN=LARP4B PE=1 SV=3 5.5 3260.2 - 1.23E+07 - - - 0.1725 - 2.769 0.648 - 158.9 1 2 0 0.0003 17 0 0 0 1.84E+08 1.59E+08 - - - 8.3375 1 221125_WJC_METTL3_EV_vs_WT_F03.19572.19572.3 6.84E-07 13/52 K.LVVEC[160.03]VMNNVTC[160.03]TR.L "sp|Q01469|FABP5_HUMAN,tr|I6L8B7|I6L8B7_HUMAN" 2 1693.795 258.63 34575 19572 3 1693.796402 565.6056 Fatty acid-binding protein 5 OS=Homo sapiens OX=9606 GN=FABP5 PE=1 SV=3 5.99 3260.3 - 4.79E+06 - - - 0.8384 - 2.154 0.549 - 205.4 1 2 0 0.0014 14 0 0 0 6.65E+07 2.57E+05 - - - 6.6996 1 221125_WJC_METTL3_EV_vs_WT_F03.19573.19573.2 3.90E-06 14/30 K.IQEGVFDINNEANGIK[136.11].L sp|P61019|RAB2A_HUMAN 1 1767.8883 1.21 34576 19573 2 1767.886617 884.9514 Ras-related protein Rab-2A OS=Homo sapiens OX=9606 GN=RAB2A PE=1 SV=1 4.14 3260.3 - 3.72E+06 - - - -0.9395 - 3.129 0.541 - 571.8 1 2 0 -0.0017 16 0 0 0 6.70E+07 5.54E+07 - - - 5.8408 0.991 221125_WJC_METTL3_EV_vs_WT_F03.19574.19574.2 8.62E-06 13/30 R.VYTADPYHALAPAASY.G "sp|O43251|RFOX2_HUMAN,tr|B0QYV1|B0QYV1_HUMAN,tr|A0A0G2JRD1|A0A0G2JRD1_HUMAN,tr|A0A0G2JRA5|A0A0G2JRA5_HUMAN,tr|S4R3K7|S4R3K7_HUMAN" 5 1708.8097 - 34577 19574 2 1708.811814 855.4121 RNA binding protein fox-1 homolog 2 OS=Homo sapiens OX=9606 GN=RBFOX2 PE=1 SV=3 5.08 3260.4 - 1.13E+06 - - - 1.2447 - 2.514 0.526 - 367.8 1 1 0 0.0021 16 0 0 0 - - - - - 5.1918 0.9999 221125_WJC_METTL3_EV_vs_WT_F03.19575.19575.3 5.73E-06 13/48 R.RLLYMAIDGVAPR.A sp|Q9H0D6|XRN2_HUMAN 1 1473.8126 1.21 34578 19575 3 1473.813248 492.2781 5'-3' exoribonuclease 2 OS=Homo sapiens OX=9606 GN=XRN2 PE=1 SV=1 8.75 3260.6 - 969422 - - - 0.437 - 2.367 0.443 - 264.1 1 2 0 0.0006 13 0 0 0 1.26E+07 1.04E+07 - - - 5.8149 0.9998 221125_WJC_METTL3_EV_vs_WT_F03.19576.19576.2 9.60E-06 22-Dec K.ESGVFEGIPTYR[166.11].F "sp|Q8WTV0|SCRB1_HUMAN,tr|B7ZKQ9|B7ZKQ9_HUMAN,tr|F5H4X0|F5H4X0_HUMAN,tr|A0A7P0T9B3|A0A7P0T9B3_HUMAN,tr|A0A7P0Z4E3|A0A7P0Z4E3_HUMAN,tr|A0A7P0T913|A0A7P0T913_HUMAN,tr|A0A7P0T9I2|A0A7P0T9I2_HUMAN" 7 1363.6648 0.95 34579 19576 2 1363.662989 682.8397 Scavenger receptor class B member 1 OS=Homo sapiens OX=9606 GN=SCARB1 PE=1 SV=1 4.53 3260.7 - 876250 - - - -1.2921 - 2.096 0.493 - 597.4 1 2 0 -0.0018 12 0 0 0 8.94E+06 9.46E+06 - - - 4.6289 0.9999 221125_WJC_METTL3_EV_vs_WT_F03.19578.19578.2 3.12E-07 13/36 R.MASPPAPSPAPPAISPIIK[136.11].N sp|Q00587|BORG5_HUMAN 1 1849.0263 3.13 34581 19578 2 1849.027586 925.5204 Cdc42 effector protein 1 OS=Homo sapiens OX=9606 GN=CDC42EP1 PE=1 SV=1 8.5 3261 - 730410 - - - 0.6998 - 2.361 0.546 - 237.1 1 2 0 0.0013 19 0 0 0 2.50E+07 8.01E+06 - - - 5.1855 0.9544 221125_WJC_METTL3_EV_vs_WT_F03.19579.19579.3 1.21 14/60 R.YGGSTIAAGVVTEIK[136.11]E.- "sp|Q9Y450|HBS1L_HUMAN,tr|H0YDX7|H0YDX7_HUMAN,tr|B7Z524|B7Z524_HUMAN,tr|J3QT46|J3QT46_HUMAN" 4 1601.8392 0.2 34582 19579 3 1601.839211 534.9537 HBS1-like protein OS=Homo sapiens OX=9606 GN=HBS1L PE=1 SV=1 4.86 3261.1 - 679720 - - - 0.005 - 1.862 0.082 - 152.6 2 2 0 0 16 0 0 0 1.07E+06 5.45E+06 - - - 0.91 1 221125_WJC_METTL3_EV_vs_WT_F03.19585.19585.2 3.02E-05 17/26 R.YGPLSGVNVVYDQR[166.11].T sp|Q13595|TRA2A_HUMAN 1 1575.7921 1.74 34587 19585 2 1575.794943 788.9033 Transformer-2 protein homolog alpha OS=Homo sapiens OX=9606 GN=TRA2A PE=1 SV=1 5.83 3261.8 - 1.60E+06 - - - 1.8188 - 3.182 0.54 - 925.8 1 2 0 0.0029 14 0 0 0 6.46E+07 3.71E+07 - - - 5.9333 0.9995 221125_WJC_METTL3_EV_vs_WT_F03.19586.19586.2 0.000389 24-Dec R.TLSFGSDLNYATR[166.11].E sp|Q14152|EIF3A_HUMAN 1 1453.7077 1.41 34588 19586 2 1453.706047 727.8611 Eukaryotic translation initiation factor 3 subunit A OS=Homo sapiens OX=9606 GN=EIF3A PE=1 SV=1 5.5 3262 - 1.31E+06 - - - -1.122 - 1.744 0.392 - 269.9 1 2 0 -0.0016 13 0 0 0 8.84E+07 6.28E+07 - - - 3.3633 1 221125_WJC_METTL3_EV_vs_WT_F03.19587.19587.3 0.000106 18/64 R.IINEPTAAAIAYGLDKR.E "sp|P11021|BIP_HUMAN,tr|A0A7P0TB36|A0A7P0TB36_HUMAN,tr|A0A7P0TAI0|A0A7P0TAI0_HUMAN" 3 1814.989 0.29 34589 19587 3 1814.992526 606.0036 Endoplasmic reticulum chaperone BiP OS=Homo sapiens OX=9606 GN=HSPA5 PE=1 SV=2 6.07 3262 - 3.01E+06 - - - 1.9163 - 3.184 0.481 - 371.9 1 2 0 0.0035 17 0 0 0 1.55E+08 5.40E+08 - - - 6.8275 0.9999 221125_WJC_METTL3_EV_vs_WT_F03.19588.19588.3 0.0361 13/68 K.LYDILGVPPGASENELKK.A "sp|O60884|DNJA2_HUMAN,tr|I3L320|I3L320_HUMAN" 2 1942.0411 0.45 34590 19588 3 1942.041392 648.3543 DnaJ homolog subfamily A member 2 OS=Homo sapiens OX=9606 GN=DNAJA2 PE=1 SV=1 4.68 3262.1 - 2.89E+06 - - - 0.1277 - 2.053 0.407 - 131.9 1 2 0 0.0002 18 0 0 0 2.99E+07 6.66E+07 - - - 4.8687 1 221125_WJC_METTL3_EV_vs_WT_F03.19589.19589.3 2.79E-10 17/68 R.KVPGVTAIELGEETC[160.03]TFR.L sp|P51116|FXR2_HUMAN 1 2006.0143 1.57 34591 19589 3 2006.016017 669.6787 Fragile X mental retardation syndrome-related protein 2 OS=Homo sapiens OX=9606 GN=FXR2 PE=1 SV=2 4.79 3262.1 - 2.39E+06 - - - 0.8674 - 3.116 0.588 - 345.4 1 2 0 0.0017 18 0 0 0 2.57E+07 1.63E+07 - - - 7.9253 1 221125_WJC_METTL3_EV_vs_WT_F03.19590.19590.3 4.47E-08 18/68 R.K[136.11]VPGVTAIELGEETC[160.03]TFR[166.11].L sp|P51116|FXR2_HUMAN 1 2024.0367 1.57 34592 19590 3 2024.037859 675.6862 Fragile X mental retardation syndrome-related protein 2 OS=Homo sapiens OX=9606 GN=FXR2 PE=1 SV=2 4.79 3262.2 - 1.69E+06 - - - 0.5494 - 3.388 0.519 - 473.9 1 2 0 0.0011 18 0 0 0 2.57E+07 1.63E+07 - - - 7.3646 1 221125_WJC_METTL3_EV_vs_WT_F03.19591.19591.3 2.86E-08 16/56 K.IFDDVSSGVSQLASK.V "sp|Q8N6T3|ARFG1_HUMAN,tr|F8VWH9|F8VWH9_HUMAN,tr|E5RHT6|E5RHT6_HUMAN,tr|F8W1U7|F8W1U7_HUMAN,tr|E5RHH7|E5RHH7_HUMAN" 5 1551.7781 1.6 34593 19591 3 1551.777154 518.2666 ADP-ribosylation factor GTPase-activating protein 1 OS=Homo sapiens OX=9606 GN=ARFGAP1 PE=1 SV=2 4.21 3262.3 - 1.59E+06 - - - -0.5793 - 2.941 0.598 - 353.7 1 2 0 -0.0009 15 0 0 0 2.79E+07 1.74E+07 - - - 8.0217 1 221125_WJC_METTL3_EV_vs_WT_F03.19592.19592.2 5.57E-08 17/30 K.TTYDSSLSSYTVPLEK.D "sp|Q8WWM7|ATX2L_HUMAN,tr|H3BSK9|H3BSK9_HUMAN,tr|H3BUF6|H3BUF6_HUMAN" 3 1789.8622 0.91 34594 19592 2 1789.859337 895.9384 Ataxin-2-like protein OS=Homo sapiens OX=9606 GN=ATXN2L PE=1 SV=2 4.37 3262.4 - 1.50E+06 - - - -1.5862 - 2.951 0.62 - 501.8 1 2 0 -0.0028 16 0 0 0 8.09E+06 8.86E+06 - - - 6.2799 0.9996 221125_WJC_METTL3_EV_vs_WT_F03.19593.19593.2 5.23E-06 16/30 K.TTYDSSLSSYTVPLEK[136.11].D "sp|Q8WWM7|ATX2L_HUMAN,tr|H3BSK9|H3BSK9_HUMAN,tr|H3BUF6|H3BUF6_HUMAN" 3 1797.8764 0.91 34595 19593 2 1797.88149 899.9455 Ataxin-2-like protein OS=Homo sapiens OX=9606 GN=ATXN2L PE=1 SV=2 4.37 3262.5 - 1.15E+06 - - - 2.8445 - 2.516 0.534 - 439 1 2 0 0.0051 16 0 0 0 8.09E+06 8.86E+06 - - - 5.2519 0.9999 221125_WJC_METTL3_EV_vs_WT_F03.19594.19594.2 4.05E-08 14/28 R.FDSNC[160.03]ITPGTEFMAR.L sp|Q8IZH2|XRN1_HUMAN 1 1744.7549 3 34596 19594 2 1744.755204 873.3847 5'-3' exoribonuclease 1 OS=Homo sapiens OX=9606 GN=XRN1 PE=1 SV=1 4.37 3262.6 - 1.05E+06 - - - 0.1794 - 2.562 0.584 - 443 1 2 0 0.0003 15 0 0 0 1.45E+07 4.84E+06 - - - 5.6673 0.9992 221125_WJC_METTL3_EV_vs_WT_F03.19595.19595.3 0.000164 Oct-52 K.IDQLQEELLHTQLK.Y "sp|O60313|OPA1_HUMAN,tr|A0A2R8YD53|A0A2R8YD53_HUMAN,tr|C9JMB8|C9JMB8_HUMAN,tr|A0A2R8YE54|A0A2R8YE54_HUMAN,tr|E5KLJ9|E5KLJ9_HUMAN,tr|A0A2R8Y4Q3|A0A2R8Y4Q3_HUMAN,tr|A0A2R8Y3X5|A0A2R8Y3X5_HUMAN,tr|A0A2R8YGE5|A0A2R8YGE5_HUMAN,tr|A0A2R8Y4G4|A0A2R8Y4G4_HUMAN,tr|A0A2R8YE78|A0A2R8YE78_HUMAN" 10 1706.9203 0.58 34597 19595 3 1706.91896 569.9807 "Dynamin-like 120 kDa protein, mitochondrial OS=Homo sapiens OX=9606 GN=OPA1 PE=1 SV=3" 4.65 3262.7 - 1.04E+06 - - - -0.785 - 2.312 0.24 - 116.9 1 2 0 -0.0013 14 0 0 0 1.04E+07 1.78E+07 - - - 3.4427 0.9999 221125_WJC_METTL3_EV_vs_WT_F03.19596.19596.2 1.10E-07 20-Dec R.QQC[160.03]AFIQFATR.Q sp|Q9NW64|RBM22_HUMAN 1 1368.6609 0.29 34598 19596 2 1368.660668 685.3377 Pre-mRNA-splicing factor RBM22 OS=Homo sapiens OX=9606 GN=RBM22 PE=1 SV=1 8.25 3262.9 - 838315 - - - -0.1366 - 2.401 0.563 - 935.2 1 2 0 -0.0002 11 0 0 0 7.80E+06 2.72E+07 - - - 5.5687 0.9999 221125_WJC_METTL3_EV_vs_WT_F03.19603.19603.2 3.30E-09 16/28 K.IFDDVSSGVSQLASK.V "sp|Q8N6T3|ARFG1_HUMAN,tr|F8VWH9|F8VWH9_HUMAN,tr|E5RHT6|E5RHT6_HUMAN,tr|F8W1U7|F8W1U7_HUMAN,tr|E5RHH7|E5RHH7_HUMAN" 5 1551.7781 1.32 34603 19603 2 1551.776924 776.8963 ADP-ribosylation factor GTPase-activating protein 1 OS=Homo sapiens OX=9606 GN=ARFGAP1 PE=1 SV=2 4.21 3263.7 - 7.55E+06 - - - -0.7276 - 2.85 0.549 - 883.7 1 2 0 -0.0011 15 0 0 0 7.00E+07 5.32E+07 - - - 5.6704 0.9997 221125_WJC_METTL3_EV_vs_WT_F03.19604.19604.3 0.0188 Nov-68 K.LYDILGVPPGASENELK[136.11]K[136.11].A "sp|O60884|DNJA2_HUMAN,tr|I3L320|I3L320_HUMAN" 2 1958.0695 0.45 34604 19604 3 1958.069605 653.6971 DnaJ homolog subfamily A member 2 OS=Homo sapiens OX=9606 GN=DNAJA2 PE=1 SV=1 4.68 3263.7 - 7.11E+06 - - - 0.0312 - 1.858 0.364 - 116.4 1 2 0 0.0001 18 0 0 0 3.18E+07 7.02E+07 - - - 4.1408 0.9999 221125_WJC_METTL3_EV_vs_WT_F03.19606.19606.2 0.000805 24-Dec R.LESLSYQLSGLQK[136.11].Q sp|Q03252|LMNB2_HUMAN 1 1472.7966 1.33 34606 19606 2 1472.796123 737.4056 Lamin-B2 OS=Homo sapiens OX=9606 GN=LMNB2 PE=1 SV=4 6 3263.9 - 2.54E+06 - - - -0.3307 - 2.51 0.456 - 531.2 1 2 0 -0.0005 13 0 0 0 2.23E+07 1.68E+07 - - - 4.7708 1 221125_WJC_METTL3_EV_vs_WT_F03.19608.19608.2 6.40E-07 14/28 K.LNIQPSEADYAVDIR[166.11].S sp|Q9NYU2|UGGG1_HUMAN 1 1712.8609 0.57 34608 19608 2 1712.860086 857.4377 UDP-glucose:glycoprotein glucosyltransferase 1 OS=Homo sapiens OX=9606 GN=UGGT1 PE=1 SV=3 4.03 3264.1 - 1.23E+06 - - - -0.4665 - 2.761 0.592 - 510.9 1 2 0 -0.0008 15 0 0 0 1.34E+07 2.33E+07 - - - 5.9101 0.9998 221125_WJC_METTL3_EV_vs_WT_F03.19612.19612.3 6.38E-08 18/60 R.VQLFEDPTVDK[136.11]EVEIR[166.11].K sp|P51948|MAT1_HUMAN 1 1934.0116 1.42 34612 19612 3 1934.013582 645.6778 CDK-activating kinase assembly factor MAT1 OS=Homo sapiens OX=9606 GN=MNAT1 PE=1 SV=1 4.18 3264.6 - 842774 - - - 1.0362 - 2.894 0.451 - 427.9 1 2 1 0.002 16 0 0 0 4.81E+07 3.38E+07 - - - 6.2942 0.9999 221125_WJC_METTL3_EV_vs_WT_F03.19616.19616.2 8.64E-07 28-Oct R.FDSNC[160.03]ITPGTEFMAR[166.11].L sp|Q8IZH2|XRN1_HUMAN 1 1754.7632 3 34616 19616 2 1754.764811 878.3889 5'-3' exoribonuclease 1 OS=Homo sapiens OX=9606 GN=XRN1 PE=1 SV=1 4.37 3265.2 - 605547 - - - 0.9403 - 2.17 0.54 - 220.7 1 2 0 0.0016 15 0 0 0 1.45E+07 4.84E+06 - - - 4.9336 0.9995 221125_WJC_METTL3_EV_vs_WT_F03.19620.19620.3 0.00241 14/48 R.ASLEAAIADAEQR[166.11].G sp|P05787|K2C8_HUMAN 1 1353.6764 2.42 34620 19620 3 1353.677884 452.2327 "Keratin, type II cytoskeletal 8 OS=Homo sapiens OX=9606 GN=KRT8 PE=1 SV=7" 4.14 3265.7 - 374048 - - - 1.1125 - 3.178 0.201 - 367.7 1 2 0 0.0015 13 0 0 0 1.75E+07 7.21E+06 - - - 3.9155 0.9999 221125_WJC_METTL3_EV_vs_WT_F03.19622.19622.2 6.19E-06 14/34 K.VGINYQPPTVVPGGDLAK[136.11].V "sp|Q9NY65|TBA8_HUMAN,sp|Q6PEY2|TBA3E_HUMAN,sp|P0DPH7|TBA3C_HUMAN,sp|Q71U36|TBA1A_HUMAN,sp|P0DPH8|TBA3D_HUMAN,sp|P68366|TBA4A_HUMAN,sp|P68363|TBA1B_HUMAN,sp|Q9BQE3|TBA1C_HUMAN,tr|A0A1W2PQM2|A0A1W2PQM2_HUMAN,tr|F5H5D3|F5H5D3_HUMAN,tr|C9J2C0|C9J2C0_HUMAN,tr|V9GZ17|V9GZ17_HUMAN,tr|A0A7P0T945|A0A7P0T945_HUMAN" 13 1831.9923 0.63 34621 19622 2 1831.990902 917.0035 Tubulin alpha-8 chain OS=Homo sapiens OX=9606 GN=TUBA8 PE=1 SV=1 5.81 3265.9 - 4.46E+07 - - - -0.7899 - 2.209 0.526 - 251.2 1 2 0 -0.0014 18 0 0 0 3.62E+08 5.79E+08 - - - 4.8741 0.9998 221125_WJC_METTL3_EV_vs_WT_F03.19624.19624.3 2.35E-07 13/56 K.DVAIKEPLVDVVDPK.Q "sp|Q99873|ANM1_HUMAN,tr|E9PQ98|E9PQ98_HUMAN,tr|E9PKG1|E9PKG1_HUMAN,tr|E9PIX6|E9PIX6_HUMAN" 4 1635.9083 5.06 34622 19624 3 1635.908884 546.3101 Protein arginine N-methyltransferase 1 OS=Homo sapiens OX=9606 GN=PRMT1 PE=1 SV=3 4.23 3266.1 - 5.41E+06 - - - 0.3338 - 2.698 0.469 - 190.8 1 2 1 0.0005 15 0 0 0 5.62E+07 1.11E+07 - - - 6.3586 0.9999 221125_WJC_METTL3_EV_vs_WT_F03.19625.19625.2 0.0256 13/24 R.ASLEAAIADAEQR.G sp|P05787|K2C8_HUMAN 1 1343.6681 2.7 34623 19625 2 1343.667147 672.8413 "Keratin, type II cytoskeletal 8 OS=Homo sapiens OX=9606 GN=KRT8 PE=1 SV=7" 4.14 3266.2 - 2.94E+06 - - - -0.7152 - 2.932 0.4 - 809.8 1 2 0 -0.001 13 0 0 0 2.23E+07 8.28E+06 - - - 4.7559 0.9999 221125_WJC_METTL3_EV_vs_WT_F03.19627.19627.3 0.0104 Dec-48 R.ASLEAAIADAEQR.G sp|P05787|K2C8_HUMAN 1 1343.6681 2.42 34625 19627 3 1343.667404 448.8966 "Keratin, type II cytoskeletal 8 OS=Homo sapiens OX=9606 GN=KRT8 PE=1 SV=7" 4.14 3266.3 - 2.21E+06 - - - -0.5239 - 2.916 0.379 - 263.2 1 2 0 -0.0007 13 0 0 0 1.75E+07 7.21E+06 - - - 5.6669 1 221125_WJC_METTL3_EV_vs_WT_F03.19628.19628.3 2.81E-09 24/56 K.R[166.11]FGFPEGSVELYAEK[136.11].V "sp|P23396|RS3_HUMAN,tr|F2Z2S8|F2Z2S8_HUMAN,tr|H0YCJ7|H0YCJ7_HUMAN,tr|E9PPU1|E9PPU1_HUMAN,tr|H0YF32|H0YF32_HUMAN" 5 1745.8744 0.76 34626 19628 3 1745.874797 582.9654 40S ribosomal protein S3 OS=Homo sapiens OX=9606 GN=RPS3 PE=1 SV=2 4.79 3266.4 - 1.95E+06 - - - 0.2526 - 3.803 0.587 - 711.2 1 2 0 0.0004 15 0 0 0 1.76E+07 2.32E+07 - - - 8.5699 0.9296 221125_WJC_METTL3_EV_vs_WT_F03.19629.19629.3 0.00658 Sep-40 G.YER[166.11]VDEIIWVK[136.11].T sp|Q86U44|MTA70_HUMAN 1 1466.7888 0.11 34627 19629 3 1466.788463 489.9369 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 4.68 3266.5 - 1.80E+06 - - - -0.2543 - 2.064 0.375 - 86.8 1 1 1 -0.0004 11 0 0 0 1.29E+06 1.21E+07 - - - 4.7794 1 221125_WJC_METTL3_EV_vs_WT_F03.19631.19631.2 0.00103 16/26 R.DVDETGITVASLER[166.11].F "sp|Q8WU90|ZC3HF_HUMAN,tr|H7C466|H7C466_HUMAN" 2 1513.7499 0.19 34629 19631 2 1513.748941 757.8822 Zinc finger CCCH domain-containing protein 15 OS=Homo sapiens OX=9606 GN=ZC3H15 PE=1 SV=1 3.92 3266.7 - 1.73E+06 - - - -0.658 - 2.947 0.591 - 512.5 1 2 0 -0.001 14 0 0 0 3.06E+06 1.57E+07 - - - 6.118 0.9998 221125_WJC_METTL3_EV_vs_WT_F03.19632.19632.2 0.000374 14/24 R.ASLEAAIADAEQR[166.11].G sp|P05787|K2C8_HUMAN 1 1353.6764 2.7 34630 19632 2 1353.675423 677.8455 "Keratin, type II cytoskeletal 8 OS=Homo sapiens OX=9606 GN=KRT8 PE=1 SV=7" 4.14 3266.8 - 1.71E+06 - - - -0.7055 - 2.987 0.323 - 943 1 2 0 -0.001 13 0 0 0 2.23E+07 8.28E+06 - - - 4.2349 1 221125_WJC_METTL3_EV_vs_WT_F03.19633.19633.3 5.47E-05 Dec-44 K.DAGQISGLNVLR[166.11].V "sp|P38646|GRP75_HUMAN,tr|H0Y8K0|H0Y8K0_HUMAN,tr|A0A7I2V2S7|A0A7I2V2S7_HUMAN,tr|A0A7I2V2G2|A0A7I2V2G2_HUMAN,tr|A0A7I2V3F7|A0A7I2V3F7_HUMAN,tr|A0A7I2YQB2|A0A7I2YQB2_HUMAN,tr|D6RCD7|D6RCD7_HUMAN" 7 1251.6811 0.38 34631 19633 3 1251.678812 418.2343 "Stress-70 protein, mitochondrial OS=Homo sapiens OX=9606 GN=HSPA9 PE=1 SV=2" 5.84 3266.8 - 1.68E+06 - - - -1.804 - 2.462 0.493 - 265 1 2 0 -0.0023 12 0 0 0 4.51E+06 1.20E+07 - - - 6.5332 0.9925 221125_WJC_METTL3_EV_vs_WT_F03.19636.19636.2 0.000396 24-Nov K.LK[136.11]EVFSMAGVVVR[166.11].A "sp|P52272|HNRPM_HUMAN,tr|M0R019|M0R019_HUMAN,tr|M0R0N3|M0R0N3_HUMAN,tr|A0A087X0X3|A0A087X0X3_HUMAN,tr|M0QZM1|M0QZM1_HUMAN,tr|M0QYQ7|M0QYQ7_HUMAN,tr|M0R2T0|M0R2T0_HUMAN" 7 1451.8289 1.51 34634 19636 2 1451.831445 726.9217 Heterogeneous nuclear ribonucleoprotein M OS=Homo sapiens OX=9606 GN=HNRNPM PE=1 SV=3 8.75 3267.2 - 988344 - - - 1.7351 - 2.158 0.326 - 294.3 1 2 1 0.0025 13 0 0 0 2.25E+07 1.49E+07 - - - 3.4222 0.9999 221125_WJC_METTL3_EV_vs_WT_F03.19637.19637.3 8.91E-05 19/60 R.ALEQLNGFELAGRPMR.V "sp|Q86U06|RBM23_HUMAN,tr|H0YJJ3|H0YJJ3_HUMAN,tr|G3XAP0|G3XAP0_HUMAN,tr|G3V5Z6|G3V5Z6_HUMAN" 4 1800.9305 1.32 34635 19637 3 1800.933177 601.3174 Probable RNA-binding protein 23 OS=Homo sapiens OX=9606 GN=RBM23 PE=1 SV=1 6.19 3267.4 - 858322 - - - 1.4931 - 3.429 0.396 - 472.3 1 2 0 0.0027 16 0 0 0 1.36E+07 1.03E+07 - - - 6.1161 0.9998 221125_WJC_METTL3_EV_vs_WT_F03.19638.19638.2 9.88E-07 Dec-32 K.FTSGAFLSPSVSVQEC[160.03]R[166.11].T "sp|P52948|NUP98_HUMAN,tr|A0A3B3ITD8|A0A3B3ITD8_HUMAN,tr|H7C3P6|H7C3P6_HUMAN" 3 1880.8966 1.5 34636 19638 2 1880.892333 941.4556 Nuclear pore complex protein Nup98-Nup96 OS=Homo sapiens OX=9606 GN=NUP98 PE=1 SV=4 5.99 3267.5 - 853315 - - - -2.2782 - 2.749 0.536 - 291.2 1 2 0 -0.0043 17 0 0 0 5.08E+06 3.40E+06 - - - 5.4847 0.9999 221125_WJC_METTL3_EV_vs_WT_F03.19640.19640.3 7.11E-06 20/52 R.HVGMAVAGLLADAR.S sp|P25788|PSA3_HUMAN 1 1379.7344 0.63 34638 19640 3 1379.729628 460.9187 Proteasome subunit alpha type-3 OS=Homo sapiens OX=9606 GN=PSMA3 PE=1 SV=2 6.74 3267.7 - 673360 - - - -3.4253 - 3.638 0.529 - 523.2 1 2 0 -0.0047 14 0 0 0 9.80E+06 1.55E+07 - - - 7.8685 0.9986 221125_WJC_METTL3_EV_vs_WT_F03.19642.19642.2 0.00416 26-Sep K.AVEYGLIQPNQDGE.- "sp|Q9H3U1|UN45A_HUMAN,tr|A0A1W2PNX8|A0A1W2PNX8_HUMAN" 2 1531.7155 - 34640 19642 2 1531.713127 766.865 Protein unc-45 homolog A OS=Homo sapiens OX=9606 GN=UNC45A PE=1 SV=1 3.91 3268 - 647714 - - - -1.5179 - 1.508 0.325 - 120.3 1 2 0 -0.0023 14 0 0 0 - - - - - 2.4716 1 221125_WJC_METTL3_EV_vs_WT_F03.19643.19643.2 5.15E-06 14/28 R.VDQSILTGESVSVIK[136.11].H "sp|P16615|AT2A2_HUMAN,sp|O14983|AT2A1_HUMAN" 2 1581.8705 1.23 34641 19643 2 1581.869955 791.9425 Sarcoplasmic\endoplasmic reticulum calcium ATPase 2 OS=Homo sapiens OX=9606 GN=ATP2A2 PE=1 SV=1 4.37 3268.1 - 578963 - - - -0.3464 - 3.106 0.556 - 769.3 1 2 0 -0.0005 15 0 0 0 3.49E+07 2.83E+07 - - - 5.9338 0.9997 221125_WJC_METTL3_EV_vs_WT_F03.19646.19646.2 1.40E-06 24-Nov R.LVQSPNSYFMDVK.C "sp|Q71UM5|RS27L_HUMAN,sp|P42677|RS27_HUMAN,tr|H0YMV8|H0YMV8_HUMAN,tr|C9JLI6|C9JLI6_HUMAN" 4 1526.7439 0.52 34643 19646 2 1526.74003 764.3792 40S ribosomal protein S27-like OS=Homo sapiens OX=9606 GN=RPS27L PE=1 SV=3 5.83 3268.5 - 925600 - - - -2.5453 - 2.285 0.569 - 351.8 1 2 0 -0.0039 13 0 0 0 1.24E+07 2.39E+07 - - - 5.3633 1 221125_WJC_METTL3_EV_vs_WT_F03.19648.19648.3 8.30E-06 15/56 K.RFGFPEGSVELYAEK.V "sp|P23396|RS3_HUMAN,tr|F2Z2S8|F2Z2S8_HUMAN,tr|H0YCJ7|H0YCJ7_HUMAN,tr|E9PPU1|E9PPU1_HUMAN,tr|H0YF32|H0YF32_HUMAN" 5 1727.8519 0.76 34645 19648 3 1727.852655 576.9579 40S ribosomal protein S3 OS=Homo sapiens OX=9606 GN=RPS3 PE=1 SV=2 4.79 3268.6 - 3.53E+06 - - - 0.4451 - 3.324 0.528 - 258.8 1 2 0 0.0008 15 0 0 0 1.76E+07 2.32E+07 - - - 7.5608 0.9999 221125_WJC_METTL3_EV_vs_WT_F03.19649.19649.3 5.64E-05 14/40 R.ELDELKPWIEK.T sp|O43395|PRPF3_HUMAN 1 1398.7395 2.12 34646 19649 3 1398.738725 467.2538 U4\U6 small nuclear ribonucleoprotein Prp3 OS=Homo sapiens OX=9606 GN=PRPF3 PE=1 SV=2 4.41 3268.6 - 3.25E+06 - - - -0.5412 - 1.898 0.468 - 255.6 1 2 0 -0.0008 11 0 0 0 1.07E+08 5.05E+07 - - - 5.5779 1 221125_WJC_METTL3_EV_vs_WT_F03.19650.19650.3 5.06E-07 Dec-44 R.ALEHFTDLYDIK[136.11].R "sp|Q00610|CLH1_HUMAN,tr|A0A087WVQ6|A0A087WVQ6_HUMAN" 2 1471.7438 0.98 34647 19650 3 1471.743719 491.5886 Clathrin heavy chain 1 OS=Homo sapiens OX=9606 GN=CLTC PE=1 SV=5 4.54 3268.6 - 3.24E+06 - - - -0.0863 - 2.879 0.569 - 194.3 1 2 0 -0.0001 12 0 0 0 1.83E+07 1.86E+07 - - - 7.8148 1 221125_WJC_METTL3_EV_vs_WT_F03.19651.19651.3 4.94E-06 14/60 R.GLIVYQLENQPSEFRR.L "sp|P78406|RAE1L_HUMAN,tr|E9PQ57|E9PQ57_HUMAN,tr|E9PPG9|E9PPG9_HUMAN" 3 1948.0167 1.43 34648 19651 3 1948.016444 650.3462 mRNA export factor OS=Homo sapiens OX=9606 GN=RAE1 PE=1 SV=1 6.14 3268.7 - 2.91E+06 - - - -0.1109 - 2.728 0.565 - 198.7 1 2 0 -0.0002 16 0 0 0 6.79E+07 4.76E+07 - - - 7.4142 1 221125_WJC_METTL3_EV_vs_WT_F03.19652.19652.3 3.51E-05 15/52 R.HVGMAVAGLLADAR[166.11].S sp|P25788|PSA3_HUMAN 1 1389.7426 0.61 34649 19652 3 1389.742772 464.2548 Proteasome subunit alpha type-3 OS=Homo sapiens OX=9606 GN=PSMA3 PE=1 SV=2 6.74 3268.8 - 2.86E+06 - - - 0.1065 - 3.1 0.525 - 301.2 1 2 0 0.0001 14 0 0 0 8.76E+06 1.43E+07 - - - 7.3999 0.9999 221125_WJC_METTL3_EV_vs_WT_F03.19654.19654.3 0.00151 Dec-40 R.ELDELK[136.11]PWIEK[136.11].T sp|O43395|PRPF3_HUMAN 1 1414.7679 2.21 34651 19654 3 1414.768616 472.5966 U4\U6 small nuclear ribonucleoprotein Prp3 OS=Homo sapiens OX=9606 GN=PRPF3 PE=1 SV=2 4.41 3268.9 - 2.09E+06 - - - 0.5188 - 2.314 0.441 - 160.2 1 2 0 0.0007 11 0 0 0 1.07E+08 4.83E+07 - - - 5.8399 0.9993 221125_WJC_METTL3_EV_vs_WT_F03.19655.19655.3 0.00199 13/60 R.GLIVYQLENQPSEFR[166.11]R[166.11].L "sp|P78406|RAE1L_HUMAN,tr|E9PQ57|E9PQ57_HUMAN,tr|E9PPG9|E9PPG9_HUMAN" 3 1968.0332 1.62 34652 19655 3 1968.028587 657.0183 mRNA export factor OS=Homo sapiens OX=9606 GN=RAE1 PE=1 SV=1 6.14 3268.9 - 2.03E+06 - - - -2.344 - 2.52 0.297 - 186.9 1 2 0 -0.0046 16 0 0 0 6.35E+07 3.91E+07 - - - 4.2215 1 221125_WJC_METTL3_EV_vs_WT_F03.19657.19657.2 2.22E-13 15/26 K.LVVEC[160.03]VMNNVTC[160.03]TR.L "sp|Q01469|FABP5_HUMAN,tr|I6L8B7|I6L8B7_HUMAN" 2 1693.795 999 34654 19657 2 1693.795831 847.9048 Fatty acid-binding protein 5 OS=Homo sapiens OX=9606 GN=FABP5 PE=1 SV=3 5.99 3269.1 - 1.68E+06 - - - 0.5012 - 3.169 0.692 - 958.7 1 2 0 0.0008 14 0 0 0 7.54E+07 0.00E+00 - - - 7.0463 1 221125_WJC_METTL3_EV_vs_WT_F03.19658.19658.2 2.73E-11 18/32 K.FTSGAFLSPSVSVQEC[160.03]R.T "sp|P52948|NUP98_HUMAN,tr|A0A3B3ITD8|A0A3B3ITD8_HUMAN,tr|H7C3P6|H7C3P6_HUMAN" 3 1870.8883 1.78 34655 19658 2 1870.890325 936.4515 Nuclear pore complex protein Nup98-Nup96 OS=Homo sapiens OX=9606 GN=NUP98 PE=1 SV=4 5.99 3269.3 - 1.36E+06 - - - 1.0567 - 3.807 0.693 - 599.9 1 2 0 0.002 17 0 0 0 1.05E+07 5.89E+06 - - - 7.4456 0.9898 221125_WJC_METTL3_EV_vs_WT_F03.19659.19659.3 0.000193 15/64 L.YVGDLHPDVTEAMLYEK.F "sp|Q9H361|PABP3_HUMAN,sp|Q4VXU2|PAP1L_HUMAN,sp|P11940|PABP1_HUMAN,tr|A0A7I2V3J9|A0A7I2V3J9_HUMAN,tr|A0A7I2V649|A0A7I2V649_HUMAN,tr|A0A6Q8JFT6|A0A6Q8JFT6_HUMAN,tr|E5RHG7|E5RHG7_HUMAN,tr|E5RFD8|E5RFD8_HUMAN,tr|H0YAR2|H0YAR2_HUMAN,tr|E7ERJ7|E7ERJ7_HUMAN,tr|E5RJB9|E5RJB9_HUMAN,tr|A0A7I2YQ88|A0A7I2YQ88_HUMAN,tr|E5RGC4|E5RGC4_HUMAN,tr|E5RJM8|E5RJM8_HUMAN,tr|E5RH24|E5RH24_HUMAN,tr|H0YBN4|H0YBN4_HUMAN,tr|A0A087WTT1|A0A087WTT1_HUMAN,tr|A0A7I2YQ90|A0A7I2YQ90_HUMAN,tr|A0A6Q8JFV4|A0A6Q8JFV4_HUMAN" 19 1978.9346 1.47 34656 19659 3 1978.934837 660.6522 Polyadenylate-binding protein 3 OS=Homo sapiens OX=9606 GN=PABPC3 PE=1 SV=2 4.31 3269.4 - 1.29E+06 - - - 0.1046 - 2.119 0.428 - 157 1 1 0 0.0002 17 0 0 0 2.18E+07 1.48E+07 - - - 5.2088 0.9995 221125_WJC_METTL3_EV_vs_WT_F03.19661.19661.3 0.0459 Dec-56 K.IIPLYSTLPPQQQQR.L sp|O43143|DHX15_HUMAN 1 1780.9836 1.84 34658 19661 3 1780.984276 594.6685 Pre-mRNA-splicing factor ATP-dependent RNA helicase DHX15 OS=Homo sapiens OX=9606 GN=DHX15 PE=1 SV=2 8.75 3269.6 - 966896 - - - 0.397 - 2.244 0.281 - 162.5 1 2 0 0.0007 15 0 0 0 1.30E+07 7.08E+06 - - - 3.7817 0.9999 221125_WJC_METTL3_EV_vs_WT_F03.19662.19662.3 0.00171 Nov-44 K.DAGQISGLNVLR.V "sp|P38646|GRP75_HUMAN,tr|H0Y8K0|H0Y8K0_HUMAN,tr|A0A7I2V2S7|A0A7I2V2S7_HUMAN,tr|A0A7I2V2G2|A0A7I2V2G2_HUMAN,tr|A0A7I2V3F7|A0A7I2V3F7_HUMAN,tr|A0A7I2YQB2|A0A7I2YQB2_HUMAN,tr|D6RCD7|D6RCD7_HUMAN" 7 1241.6728 0.38 34659 19662 3 1241.672364 414.8982 "Stress-70 protein, mitochondrial OS=Homo sapiens OX=9606 GN=HSPA9 PE=1 SV=2" 5.84 3269.7 - 929234 - - - -0.3511 - 2.475 0.361 - 151.3 1 2 0 -0.0004 12 0 0 0 4.51E+06 1.20E+07 - - - 5.0766 0.981 221125_WJC_METTL3_EV_vs_WT_F03.19664.19664.3 0.000203 13/48 A.VITVPAYFNDSQR[166.11].Q "sp|P38646|GRP75_HUMAN,sp|P54652|HSP72_HUMAN,sp|P0DMV8|HS71A_HUMAN,sp|P34931|HS71L_HUMAN,sp|P0DMV9|HS71B_HUMAN,sp|P17066|HSP76_HUMAN,tr|H0Y8K0|H0Y8K0_HUMAN,tr|A0A7I2V2S7|A0A7I2V2S7_HUMAN,tr|A0A7I2V2G2|A0A7I2V2G2_HUMAN,tr|Q53FA3|Q53FA3_HUMAN,tr|A0A7I2V3F7|A0A7I2V3F7_HUMAN,tr|A0A7I2YQB2|A0A7I2YQB2_HUMAN,tr|A0A0G2JIW1|A0A0G2JIW1_HUMAN,tr|D6RCD7|D6RCD7_HUMAN" 14 1518.7706 0.24 34661 19664 3 1518.766543 507.2641 "Stress-70 protein, mitochondrial OS=Homo sapiens OX=9606 GN=HSPA9 PE=1 SV=2" 5.81 3270 - 728121 - - - -2.6798 - 2.453 0.421 - 176.4 1 1 0 -0.0041 13 0 0 0 1.57E+06 6.49E+06 - - - 5.6655 1 221125_WJC_METTL3_EV_vs_WT_F03.19666.19666.2 8.65E-07 15/32 R.MLGETC[160.03]ADC[160.03]GTILLQDK[136.11].Q "sp|O60232|ZNRD2_HUMAN,tr|H0YEK1|H0YEK1_HUMAN,tr|E9PN57|E9PN57_HUMAN,tr|H0YEB6|H0YEB6_HUMAN,tr|G3V1B8|G3V1B8_HUMAN" 5 1931.8882 -1 34662 19666 2 1931.886618 966.9514 Protein ZNRD2 OS=Homo sapiens OX=9606 GN=ZNRD2 PE=1 SV=1 4.03 3270.2 - 339801 - - - -0.8298 - 3.309 0.68 - 634.6 1 2 0 -0.0016 17 0 0 0 0.00E+00 0.00E+00 - - - 7.005 0.9997 221125_WJC_METTL3_EV_vs_WT_F03.19667.19667.3 7.29E-05 Dec-56 R.VDQSILTGESVSVIK[136.11].H "sp|P16615|AT2A2_HUMAN,sp|O14983|AT2A1_HUMAN" 2 1581.8705 2.11 34663 19667 3 1581.870994 528.2974 Sarcoplasmic\endoplasmic reticulum calcium ATPase 2 OS=Homo sapiens OX=9606 GN=ATP2A2 PE=1 SV=1 4.37 3270.3 - 832623 - - - 0.3104 - 2.419 0.316 - 191.5 1 2 0 0.0005 15 0 0 0 6.72E+06 3.18E+06 - - - 4.3679 0.9999 221125_WJC_METTL3_EV_vs_WT_F03.19669.19669.3 7.65E-05 13/44 R.TRLGLEDFESLK.V sp|Q15208|STK38_HUMAN 1 1406.7405 3.51 34665 19669 3 1406.740919 469.9208 Serine\threonine-protein kinase 38 OS=Homo sapiens OX=9606 GN=STK38 PE=1 SV=1 4.68 3270.4 - 7.35E+06 - - - 0.2659 - 2.766 0.5 - 385.4 1 2 1 0.0004 12 0 0 0 9.46E+07 2.69E+07 - - - 6.9345 1 221125_WJC_METTL3_EV_vs_WT_F03.19670.19670.2 1.37E-08 13/28 R.VDQSILTGESVSVIK.H "sp|P16615|AT2A2_HUMAN,sp|O14983|AT2A1_HUMAN" 2 1573.8563 1.23 34666 19670 2 1573.857839 787.9354 Sarcoplasmic\endoplasmic reticulum calcium ATPase 2 OS=Homo sapiens OX=9606 GN=ATP2A2 PE=1 SV=1 4.37 3270.4 - 5.53E+06 - - - 0.9759 - 3.166 0.59 - 550.2 1 2 0 0.0015 15 0 0 0 3.49E+07 2.83E+07 - - - 6.2317 0.999 221125_WJC_METTL3_EV_vs_WT_F03.19671.19671.3 2.73E-06 15/56 K.DVAIK[136.11]EPLVDVVDPK[136.11].Q "sp|Q99873|ANM1_HUMAN,tr|E9PQ98|E9PQ98_HUMAN,tr|E9PKG1|E9PKG1_HUMAN,tr|E9PIX6|E9PIX6_HUMAN" 4 1651.9367 4.86 34667 19671 3 1651.929512 551.6529 Protein arginine N-methyltransferase 1 OS=Homo sapiens OX=9606 GN=PRMT1 PE=1 SV=3 4.23 3270.5 - 3.65E+06 - - - -4.3743 - 2.714 0.522 - 232.5 1 2 1 -0.0072 15 0 0 0 4.71E+07 9.68E+06 - - - 6.963 0.9997 221125_WJC_METTL3_EV_vs_WT_F03.19672.19672.3 0.00043 13/44 R.TR[166.11]LGLEDFESLK[136.11].V sp|Q15208|STK38_HUMAN 1 1424.763 3.5 34668 19672 3 1424.762847 475.9283 Serine\threonine-protein kinase 38 OS=Homo sapiens OX=9606 GN=STK38 PE=1 SV=1 4.68 3270.5 - 2.85E+06 - - - -0.1179 - 2.703 0.383 - 355.1 1 2 1 -0.0002 12 0 0 0 9.36E+07 2.68E+07 - - - 5.5663 0.9963 221125_WJC_METTL3_EV_vs_WT_F03.19673.19673.3 0.000465 Dec-64 L.YVGDLHPDVTEAMLYEK[136.11].F "sp|Q9H361|PABP3_HUMAN,sp|Q4VXU2|PAP1L_HUMAN,sp|P11940|PABP1_HUMAN,tr|A0A7I2V3J9|A0A7I2V3J9_HUMAN,tr|A0A7I2V649|A0A7I2V649_HUMAN,tr|A0A6Q8JFT6|A0A6Q8JFT6_HUMAN,tr|E5RHG7|E5RHG7_HUMAN,tr|E5RFD8|E5RFD8_HUMAN,tr|H0YAR2|H0YAR2_HUMAN,tr|E7ERJ7|E7ERJ7_HUMAN,tr|E5RJB9|E5RJB9_HUMAN,tr|A0A7I2YQ88|A0A7I2YQ88_HUMAN,tr|E5RGC4|E5RGC4_HUMAN,tr|E5RJM8|E5RJM8_HUMAN,tr|E5RH24|E5RH24_HUMAN,tr|H0YBN4|H0YBN4_HUMAN,tr|A0A087WTT1|A0A087WTT1_HUMAN,tr|A0A7I2YQ90|A0A7I2YQ90_HUMAN,tr|A0A6Q8JFV4|A0A6Q8JFV4_HUMAN" 19 1986.9488 1.47 34669 19673 3 1986.948894 663.3236 Polyadenylate-binding protein 3 OS=Homo sapiens OX=9606 GN=PABPC3 PE=1 SV=2 4.31 3270.6 - 2.61E+06 - - - 0.0322 - 2.3 0.509 - 85.8 1 1 0 0.0001 17 0 0 0 2.18E+07 1.48E+07 - - - 6.319 0.9977 221125_WJC_METTL3_EV_vs_WT_F03.19675.19675.2 0.179 14-Aug K.DLTEYLSR[166.11].F "sp|O14979|HNRDL_HUMAN,tr|A0A087WUK2|A0A087WUK2_HUMAN" 2 1005.5006 1.24 34671 19675 2 1005.500577 503.7576 Heterogeneous nuclear ribonucleoprotein D-like OS=Homo sapiens OX=9606 GN=HNRNPDL PE=1 SV=3 4.37 3270.7 - 2.04E+06 - - - -0.0676 - 1.584 0.171 - 268.5 1 2 0 -0.0001 8 0 0 0 1.27E+07 1.03E+07 - - - 1.6912 0.9995 221125_WJC_METTL3_EV_vs_WT_F03.19677.19677.3 0.00322 Nov-56 R.YYKPEDLPETVPYLK.L "sp|O75319|DUS11_HUMAN,tr|H7C0E6|H7C0E6_HUMAN" 2 1853.9451 2.02 34673 19677 3 1853.94821 618.989 RNA\RNP complex-1-interacting phosphatase OS=Homo sapiens OX=9606 GN=DUSP11 PE=1 SV=2 4.68 3270.9 - 1.71E+06 - - - 1.6678 - 2.078 0.335 - 87 1 2 0 0.0031 15 0 0 0 3.41E+07 1.68E+07 - - - 4.1826 0.9998 221125_WJC_METTL3_EV_vs_WT_F03.19680.19680.3 0.00193 15/48 K.AFSQFVRPLIAAK.N "sp|Q14839|CHD4_HUMAN,tr|A0A2U3TZM0|A0A2U3TZM0_HUMAN,tr|A0A2R8Y685|A0A2R8Y685_HUMAN,tr|A0A2R8Y445|A0A2R8Y445_HUMAN,tr|F5H6N4|F5H6N4_HUMAN,tr|A0A2R8Y5J0|A0A2R8Y5J0_HUMAN,tr|A0A2R8Y425|A0A2R8Y425_HUMAN,tr|A0A2R8YFK9|A0A2R8YFK9_HUMAN,tr|A0A2R8Y8B3|A0A2R8Y8B3_HUMAN,tr|A0A2R8Y8C1|A0A2R8Y8C1_HUMAN,tr|A0A0C4DGG9|A0A0C4DGG9_HUMAN,tr|A0A2R8YFD8|A0A2R8YFD8_HUMAN,tr|A0A2R8Y5Z7|A0A2R8Y5Z7_HUMAN,tr|F5GWX5|F5GWX5_HUMAN,tr|A0A2R8YER1|A0A2R8YER1_HUMAN,tr|A0A2R8Y521|A0A2R8Y521_HUMAN,tr|A0A2R8Y212|A0A2R8Y212_HUMAN" 17 1446.8347 0.61 34676 19680 3 1446.835107 483.2855 Chromodomain-helicase-DNA-binding protein 4 OS=Homo sapiens OX=9606 GN=CHD4 PE=1 SV=2 11 3271.2 - 1.37E+06 - - - 0.2675 - 1.957 0.375 - 156.2 1 2 0 0.0004 13 0 0 0 5.96E+06 9.80E+06 - - - 4.5412 1 221125_WJC_METTL3_EV_vs_WT_F03.19681.19681.2 3.09E-10 14/28 R.AQFFVEDASTASALK[136.11].A "sp|Q9UBU9|NXF1_HUMAN,tr|B4E227|B4E227_HUMAN,tr|E9PLA7|E9PLA7_HUMAN,tr|E9PIN3|E9PIN3_HUMAN" 4 1591.7973 1.25 34677 19681 2 1591.792336 796.9059 Nuclear RNA export factor 1 OS=Homo sapiens OX=9606 GN=NXF1 PE=1 SV=1 4.37 3271.3 - 1.17E+06 - - - -3.1424 - 2.864 0.634 - 444.3 1 2 0 -0.005 15 0 0 0 2.37E+07 1.90E+07 - - - 6.3091 1 221125_WJC_METTL3_EV_vs_WT_F03.19684.19684.2 1.32E-07 14/22 R.ALEHFTDLYDIK[136.11].R "sp|Q00610|CLH1_HUMAN,tr|A0A087WVQ6|A0A087WVQ6_HUMAN" 2 1471.7438 0.08 34680 19684 2 1471.740832 736.8792 Clathrin heavy chain 1 OS=Homo sapiens OX=9606 GN=CLTC PE=1 SV=5 4.54 3271.7 - 615336 - - - -2.0479 - 2.899 0.565 - 727.9 1 2 0 -0.003 12 0 0 0 8.47E+06 1.02E+08 - - - 6.0137 0.9999 221125_WJC_METTL3_EV_vs_WT_F03.19687.19687.3 0.000886 13/40 K.DLFDYSPPLHK.N "sp|Q9NYF8|BCLF1_HUMAN,tr|E9PKI6|E9PKI6_HUMAN,tr|A0A1W2PQ43|A0A1W2PQ43_HUMAN,tr|E9PK91|E9PK91_HUMAN,tr|E9PK09|E9PK09_HUMAN,tr|E9PQN2|E9PQN2_HUMAN" 6 1330.6558 2.61 34682 19687 3 1330.656805 444.5592 Bcl-2-associated transcription factor 1 OS=Homo sapiens OX=9606 GN=BCLAF1 PE=1 SV=2 5.21 3272 - 880725 - - - 0.7913 - 1.918 0.426 - 194.8 1 2 0 0.0011 11 0 0 0 3.11E+08 1.19E+08 - - - 5.1394 0.9995 221125_WJC_METTL3_EV_vs_WT_F03.19688.19688.2 1.71E-05 Nov-32 K.LASQADSTEQVDDTILT.- sp|Q92616|GCN1_HUMAN 1 1805.8531 - 34683 19688 2 1805.847848 903.9338 eIF-2-alpha kinase activator GCN1 OS=Homo sapiens OX=9606 GN=GCN1 PE=1 SV=6 3.37 3272.1 - 621836 - - - -2.8906 - 2.122 0.541 - 306.9 1 2 0 -0.0052 17 0 0 0 - - - - - 4.8849 0.9999 221125_WJC_METTL3_EV_vs_WT_F03.19689.19689.3 0.004 16/60 K.IYGADDIELLPEAQHK.A "sp|P11586|C1TC_HUMAN,tr|F5H2F4|F5H2F4_HUMAN,tr|V9GZ78|V9GZ78_HUMAN,tr|V9GYY3|V9GYY3_HUMAN" 4 1810.9101 1.19 34684 19689 3 1810.912089 604.644 "C-1-tetrahydrofolate synthase, cytoplasmic OS=Homo sapiens OX=9606 GN=MTHFD1 PE=1 SV=4" 4.31 3272.2 - 8.73E+06 - - - 1.0823 - 2.824 0.388 - 305 1 2 0 0.002 16 0 0 0 6.40E+07 5.40E+07 - - - 5.529 0.9948 221125_WJC_METTL3_EV_vs_WT_F03.19691.19691.2 0.205 14-Jul K.DLTEYLSR.F "sp|O14979|HNRDL_HUMAN,tr|A0A087WUK2|A0A087WUK2_HUMAN" 2 995.4924 1.24 34686 19691 2 995.492177 498.7535 Heterogeneous nuclear ribonucleoprotein D-like OS=Homo sapiens OX=9606 GN=HNRNPDL PE=1 SV=3 4.37 3272.4 - 1.59E+06 - - - -0.1989 - 1.428 0.13 - 175.7 1 2 0 -0.0002 8 0 0 0 1.27E+07 1.03E+07 - - - 1.0756 0.768 221125_WJC_METTL3_EV_vs_WT_F03.19692.19692.2 0.00181 20-Oct R.FRC[160.03]PEALFQPS.F "sp|P63261|ACTG_HUMAN,sp|Q562R1|ACTBL_HUMAN,sp|P60709|ACTB_HUMAN,tr|A0A804GS07|A0A804GS07_HUMAN,tr|E7EVS6|E7EVS6_HUMAN,tr|A0A6Q8PFE4|A0A6Q8PFE4_HUMAN,tr|A0A2R8YEA7|A0A2R8YEA7_HUMAN,tr|A0A2R8Y793|A0A2R8Y793_HUMAN,tr|I3L4N8|I3L4N8_HUMAN" 9 1350.6391 1.33 34687 19692 2 1350.640574 676.3268 "Actin, cytoplasmic 2 OS=Homo sapiens OX=9606 GN=ACTG1 PE=1 SV=1" 5.99 3272.4 - 1.41E+06 - - - 1.1232 - 1.84 0.381 - 269.9 1 1 1 0.0015 11 0 0 0 1.22E+07 9.19E+06 - - - 3.5041 0.9997 221125_WJC_METTL3_EV_vs_WT_F03.19695.19695.3 2.84E-05 Dec-44 K.VVLLTEVDK[136.11]LTK[136.11].D sp|P40938|RFC3_HUMAN 1 1372.8512 0.18 34690 19695 3 1372.850043 458.6243 Replication factor C subunit 3 OS=Homo sapiens OX=9606 GN=RFC3 PE=1 SV=2 6.04 3272.8 - 886002 - - - -0.8559 - 2.374 0.418 - 174.5 1 2 1 -0.0012 12 0 0 0 6.94E+05 3.81E+06 - - - 5.5964 0.9999 221125_WJC_METTL3_EV_vs_WT_F03.19696.19696.3 9.22E-06 Dec-48 K.GYFDAHALAMDYR.S "sp|Q9Y5J3|HEY1_HUMAN,tr|E5RHK6|E5RHK6_HUMAN,tr|A0A6I8PRS3|A0A6I8PRS3_HUMAN,tr|A0A6I8PRC2|A0A6I8PRC2_HUMAN,tr|B4DEI9|B4DEI9_HUMAN" 5 1528.6769 1.19 34691 19696 3 1528.680737 510.5662 Hairy\enhancer-of-split related with YRPW motif protein 1 OS=Homo sapiens OX=9606 GN=HEY1 PE=1 SV=1 5.21 3272.9 - 848146 - - - 2.5107 - 1.978 0.529 - 139.6 1 2 0 0.0038 13 0 0 0 3.33E+06 2.79E+06 - - - 6.2861 0.9954 221125_WJC_METTL3_EV_vs_WT_F03.19697.19697.3 0.000696 13/48 K.LLNPDDLREEIVK.A sp|Q86XL3|ANKL2_HUMAN 1 1552.8461 1.24 34692 19697 3 1552.846512 518.6226 Ankyrin repeat and LEM domain-containing protein 2 OS=Homo sapiens OX=9606 GN=ANKLE2 PE=1 SV=4 4.32 3273 - 811837 - - - 0.2827 - 2.08 0.249 - 178.4 1 2 1 0.0004 13 0 0 0 2.87E+06 2.31E+06 - - - 3.3016 0.9991 221125_WJC_METTL3_EV_vs_WT_F03.19698.19698.3 0.00654 Oct-44 R.LKLPAVVTADLR.L "sp|P38117|ETFB_HUMAN,tr|M0QY67|M0QY67_HUMAN" 2 1294.7973 1.72 34693 19698 3 1294.796792 432.6064 Electron transfer flavoprotein subunit beta OS=Homo sapiens OX=9606 GN=ETFB PE=1 SV=3 8.75 3273.1 - 807132 - - - -0.3707 - 2.121 0.356 - 152.6 1 2 1 -0.0005 12 0 0 0 4.92E+07 2.86E+07 - - - 4.593 0.9996 221125_WJC_METTL3_EV_vs_WT_F03.19699.19699.3 0.00051 Oct-44 R.KYAVLYQPLFDK.R "sp|P55209|NP1L1_HUMAN,tr|F8VUX1|F8VUX1_HUMAN,tr|F8W543|F8W543_HUMAN,tr|F8W118|F8W118_HUMAN,tr|F8VRJ2|F8VRJ2_HUMAN,tr|F8W0J6|F8W0J6_HUMAN,tr|F8VV59|F8VV59_HUMAN,tr|B7Z9C2|B7Z9C2_HUMAN,tr|F8VXI6|F8VXI6_HUMAN,tr|H0YHC3|H0YHC3_HUMAN,tr|H0YIV4|H0YIV4_HUMAN,tr|F5H4R6|F5H4R6_HUMAN,tr|H0YH88|H0YH88_HUMAN,tr|F8W020|F8W020_HUMAN,tr|F8VVB5|F8VVB5_HUMAN,tr|F8VY35|F8VY35_HUMAN" 16 1483.8075 0.83 34694 19699 3 1483.809146 495.6098 Nucleosome assembly protein 1-like 1 OS=Homo sapiens OX=9606 GN=NAP1L1 PE=1 SV=1 8.43 3273.2 - 785740 - - - 1.108 - 2.058 0.329 - 118.1 1 2 0 0.0016 12 0 0 0 2.62E+07 3.15E+07 - - - 4.2081 0.9961 221125_WJC_METTL3_EV_vs_WT_F03.19702.19702.2 0.405 20-Aug K.HPFAIENIIAR.E sp|Q99853|FOXB1_HUMAN 1 1279.7037 1.08 34697 19702 2 1279.704932 640.8591 Forkhead box protein B1 OS=Homo sapiens OX=9606 GN=FOXB1 PE=1 SV=3 6.75 3273.6 - 588101 - - - 0.958 - 1.458 0.192 - 175 1 2 0 0.0012 11 0 0 0 3.57E+06 3.30E+06 - - - 1.4788 0.9979 221125_WJC_METTL3_EV_vs_WT_F03.19706.19706.2 0.00245 28-Dec K.DVAIKEPLVDVVDPK.Q "sp|Q99873|ANM1_HUMAN,tr|E9PQ98|E9PQ98_HUMAN,tr|E9PKG1|E9PKG1_HUMAN,tr|E9PIX6|E9PIX6_HUMAN" 4 1635.9083 5.56 34701 19706 2 1635.906939 818.9614 Protein arginine N-methyltransferase 1 OS=Homo sapiens OX=9606 GN=PRMT1 PE=1 SV=3 4.23 3274.1 - 430130 - - - -0.8552 - 2.151 0.464 - 362.5 1 2 1 -0.0014 15 0 0 0 2.94E+06 5.28E+05 - - - 4.3507 0.9998 221125_WJC_METTL3_EV_vs_WT_F03.19708.19708.2 3.82E-05 22-Oct K.DAGQISGLNVLR[166.11].V "sp|P38646|GRP75_HUMAN,tr|H0Y8K0|H0Y8K0_HUMAN,tr|A0A7I2V2S7|A0A7I2V2S7_HUMAN,tr|A0A7I2V2G2|A0A7I2V2G2_HUMAN,tr|A0A7I2V3F7|A0A7I2V3F7_HUMAN,tr|A0A7I2YQB2|A0A7I2YQB2_HUMAN,tr|D6RCD7|D6RCD7_HUMAN" 7 1251.6811 0.43 34702 19708 2 1251.681494 626.8478 "Stress-70 protein, mitochondrial OS=Homo sapiens OX=9606 GN=HSPA9 PE=1 SV=2" 5.84 3274.4 - 3.90E+06 - - - 0.3387 - 2.047 0.431 - 285.1 1 2 0 0.0004 12 0 0 0 3.42E+08 8.04E+08 - - - 4.1091 1 221125_WJC_METTL3_EV_vs_WT_F03.19710.19710.2 4.31E-12 15/28 R.AQFFVEDASTASALK.A "sp|Q9UBU9|NXF1_HUMAN,tr|B4E227|B4E227_HUMAN,tr|E9PLA7|E9PLA7_HUMAN,tr|E9PIN3|E9PIN3_HUMAN" 4 1583.7831 1.2 34704 19710 2 1583.782606 792.8988 Nuclear RNA export factor 1 OS=Homo sapiens OX=9606 GN=NXF1 PE=1 SV=1 4.37 3274.5 - 3.48E+06 - - - -0.3359 - 3.099 0.715 - 590.5 1 2 0 -0.0005 15 0 0 0 2.45E+07 2.04E+07 - - - 7.1026 0.988 221125_WJC_METTL3_EV_vs_WT_F03.19712.19712.2 0.00787 15/22 R.TRLGLEDFESLK.V sp|Q15208|STK38_HUMAN 1 1406.7405 2.22 34706 19712 2 1406.74485 704.3775 Serine\threonine-protein kinase 38 OS=Homo sapiens OX=9606 GN=STK38 PE=1 SV=1 4.68 3274.6 - 2.16E+06 - - - 3.0603 - 2.491 0.336 - 539.4 1 2 1 0.0043 12 0 0 0 1.17E+07 5.28E+06 - - - 3.9228 0.9901 221125_WJC_METTL3_EV_vs_WT_F03.19713.19713.2 0.0215 20-Oct R.ELDELKPWIEK.T sp|O43395|PRPF3_HUMAN 1 1398.7395 2.03 34707 19713 2 1398.748546 700.377 U4\U6 small nuclear ribonucleoprotein Prp3 OS=Homo sapiens OX=9606 GN=PRPF3 PE=1 SV=2 4.41 3274.6 - 1.98E+06 - - - 6.4801 - 2.356 0.378 - 288 1 2 0 0.0091 11 0 0 0 1.19E+07 5.83E+06 - - - 4.1484 1 221125_WJC_METTL3_EV_vs_WT_F03.19715.19715.3 7.69E-06 Nov-44 R.ALEHFTDLYDIK.R "sp|Q00610|CLH1_HUMAN,tr|A0A087WVQ6|A0A087WVQ6_HUMAN" 2 1463.7296 0.88 34709 19715 3 1463.730957 488.9172 Clathrin heavy chain 1 OS=Homo sapiens OX=9606 GN=CLTC PE=1 SV=5 4.54 3274.8 - 1.50E+06 - - - 0.8957 - 2.182 0.504 - 137.7 1 2 0 0.0013 12 0 0 0 1.86E+07 2.11E+07 - - - 6.3215 0.9999 221125_WJC_METTL3_EV_vs_WT_F03.19716.19716.3 0.000363 Nov-48 R.LIHQTNLILQTFK[136.11].T "sp|Q9BUL8|PDC10_HUMAN,tr|C9J363|C9J363_HUMAN" 2 1575.9228 1.48 34710 19716 3 1575.922916 526.3149 Programmed cell death protein 10 OS=Homo sapiens OX=9606 GN=PDCD10 PE=1 SV=1 8.76 3274.9 - 638507 - - - 0.0654 - 2.404 0.391 - 183.1 1 2 0 0.0001 13 0 0 0 3.99E+06 2.70E+06 - - - 5.2774 0.9983 221125_WJC_METTL3_EV_vs_WT_F03.19718.19718.3 0.00344 Aug-48 K.GYFDAHALAMDYR[166.11].S "sp|Q9Y5J3|HEY1_HUMAN,tr|E5RHK6|E5RHK6_HUMAN,tr|A0A6I8PRS3|A0A6I8PRS3_HUMAN,tr|A0A6I8PRC2|A0A6I8PRC2_HUMAN,tr|B4DEI9|B4DEI9_HUMAN" 5 1538.6852 1.19 34712 19718 3 1538.687583 513.9023 Hairy\enhancer-of-split related with YRPW motif protein 1 OS=Homo sapiens OX=9606 GN=HEY1 PE=1 SV=1 5.21 3275.1 - 467126 - - - 1.5689 - 1.486 0.322 - 62.3 1 2 0 0.0024 13 0 0 0 3.33E+06 2.79E+06 - - - 3.2032 1 221125_WJC_METTL3_EV_vs_WT_F03.19719.19719.3 1.13E-07 21/72 K.AAQLVLTGGTGSHGVFLVR[166.11].Q "sp|Q9NRF2|SH2B1_HUMAN,tr|B4DLN5|B4DLN5_HUMAN,tr|H3BUN7|H3BUN7_HUMAN,tr|F5GXU7|F5GXU7_HUMAN" 4 1892.0508 30.81 34713 19719 3 1892.051722 631.6909 SH2B adapter protein 1 OS=Homo sapiens OX=9606 GN=SH2B1 PE=1 SV=3 9.8 3275.3 - 435102 - - - 0.5132 - 4.003 0.57 - 549.4 1 2 0 0.001 19 0 0 0 7.24E+07 2.35E+06 - - - 8.3024 0.9904 221125_WJC_METTL3_EV_vs_WT_F03.19720.19720.3 0.0109 Sep-36 R.HSLLQTLYK[136.11]V.- sp|P46060|RAGP1_HUMAN 1 1208.7009 0.98 34714 19720 3 1208.704507 403.9076 Ran GTPase-activating protein 1 OS=Homo sapiens OX=9606 GN=RANGAP1 PE=1 SV=1 8.6 3275.4 - 332485 - - - 3.0181 - 1.641 0.242 - 109.2 1 2 0 0.0036 10 0 0 0 2.18E+06 2.21E+06 - - - 2.6836 1 221125_WJC_METTL3_EV_vs_WT_F03.19724.19724.2 1.26E-06 17/30 K.TITLEVEPSDTIENVK.A "sp|P62979|RS27A_HUMAN,sp|P0CG48|UBC_HUMAN,sp|P0CG47|UBB_HUMAN,sp|P62987|RL40_HUMAN,tr|F5H388|F5H388_HUMAN,tr|F5GYU3|F5GYU3_HUMAN,tr|B4DV12|B4DV12_HUMAN,tr|J3QSA3|J3QSA3_HUMAN,tr|Q5PY61|Q5PY61_HUMAN,tr|F5H2Z3|F5H2Z3_HUMAN,tr|J3QS39|J3QS39_HUMAN,tr|J3QTR3|J3QTR3_HUMAN,tr|Q96C32|Q96C32_HUMAN,tr|M0R1V7|M0R1V7_HUMAN,tr|F5H747|F5H747_HUMAN,tr|F5H747|F5H747_HUMAN,tr|F5GXK7|F5GXK7_HUMAN,tr|F5GXK7|F5GXK7_HUMAN,tr|F5H6Q2|F5H6Q2_HUMAN,tr|F5GZ39|F5GZ39_HUMAN,tr|J3QKN0|J3QKN0_HUMAN,tr|J3QKN0|J3QKN0_HUMAN,tr|J3QKN0|J3QKN0_HUMAN,tr|F5H265|F5H265_HUMAN" 24 1786.92 0.69 34716 19724 2 1786.921383 894.4673 Ubiquitin-40S ribosomal protein S27a OS=Homo sapiens OX=9606 GN=RPS27A PE=1 SV=2 4 3275.8 - 4.83E+06 - - - 0.76 - 3.511 0.536 - 739.2 1 2 0 0.0014 16 0 0 0 1.18E+09 1.71E+09 - - - 6.0872 0.9998 221125_WJC_METTL3_EV_vs_WT_F03.19725.19725.2 0.000158 18-Oct K.FAAQELIEVK[136.11].R "sp|Q86U44|MTA70_HUMAN,tr|F5H6D8|F5H6D8_HUMAN,tr|H0YFV6|H0YFV6_HUMAN,tr|B4DTN4|B4DTN4_HUMAN" 4 1154.6427 0.06 34717 19725 2 1154.642028 578.3286 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 4.53 3275.9 - 1.93E+06 - - - -0.5603 - 1.997 0.468 - 247.1 1 2 0 -0.0006 10 0 0 0 6.95E+05 1.12E+07 - - - 4.428 0.9994 221125_WJC_METTL3_EV_vs_WT_F03.19728.19728.3 0.00794 13/60 K.TITLEVEPSDTIENVK.A "sp|P62979|RS27A_HUMAN,sp|P0CG48|UBC_HUMAN,sp|P0CG47|UBB_HUMAN,sp|P62987|RL40_HUMAN,tr|F5H388|F5H388_HUMAN,tr|F5GYU3|F5GYU3_HUMAN,tr|B4DV12|B4DV12_HUMAN,tr|J3QSA3|J3QSA3_HUMAN,tr|Q5PY61|Q5PY61_HUMAN,tr|F5H2Z3|F5H2Z3_HUMAN,tr|J3QS39|J3QS39_HUMAN,tr|J3QTR3|J3QTR3_HUMAN,tr|Q96C32|Q96C32_HUMAN,tr|M0R1V7|M0R1V7_HUMAN,tr|F5H747|F5H747_HUMAN,tr|F5H747|F5H747_HUMAN,tr|F5GXK7|F5GXK7_HUMAN,tr|F5GXK7|F5GXK7_HUMAN,tr|F5H6Q2|F5H6Q2_HUMAN,tr|F5GZ39|F5GZ39_HUMAN,tr|J3QKN0|J3QKN0_HUMAN,tr|J3QKN0|J3QKN0_HUMAN,tr|J3QKN0|J3QKN0_HUMAN,tr|F5H265|F5H265_HUMAN" 24 1786.92 0.65 34720 19728 3 1786.913588 596.6473 Ubiquitin-40S ribosomal protein S27a OS=Homo sapiens OX=9606 GN=RPS27A PE=1 SV=2 4 3276.1 - 1.26E+06 - - - -3.6023 - 2.438 0.385 - 152.6 1 2 0 -0.0064 16 0 0 0 2.39E+08 3.68E+08 - - - 5.1172 0.9999 221125_WJC_METTL3_EV_vs_WT_F03.19729.19729.3 4.07E-06 16/60 K.AQQEFAAGVFSNPAVR[166.11].T sp|O14828|SCAM3_HUMAN 1 1700.851 1.5 34721 19729 3 1700.850441 567.9576 Secretory carrier-associated membrane protein 3 OS=Homo sapiens OX=9606 GN=SCAMP3 PE=1 SV=3 6.05 3276.2 - 1.13E+06 - - - -0.3216 - 2.27 0.469 - 205.2 1 2 0 -0.0005 16 0 0 0 7.47E+06 4.99E+06 - - - 5.8722 1 221125_WJC_METTL3_EV_vs_WT_F03.19730.19730.3 5.99E-10 19/72 R.LEGMLSQSVSSQYNMAGVR.T "sp|P54105|ICLN_HUMAN,tr|J3KN38|J3KN38_HUMAN,tr|E9PMI6|E9PMI6_HUMAN" 3 2055.9718 1.34 34722 19730 3 2055.972969 686.3312 Methylosome subunit pICln OS=Homo sapiens OX=9606 GN=CLNS1A PE=1 SV=1 6 3276.3 - 1.10E+06 - - - 0.588 - 3.23 0.601 - 550.6 1 2 0 0.0012 19 0 0 0 1.36E+07 1.02E+07 - - - 8.1208 1 221125_WJC_METTL3_EV_vs_WT_F03.19731.19731.2 2.09E-09 21/24 K.K[136.11]YDAFLASESLIK[136.11].Q sp|P62906|RL10A_HUMAN 1 1499.8206 1.23 34723 19731 2 1499.82267 750.9176 60S ribosomal protein L10a OS=Homo sapiens OX=9606 GN=RPL10A PE=1 SV=2 6.07 3276.5 - 1.07E+06 - - - 1.3495 - 4.235 0.601 - 1324.5 1 2 0 0.002 13 0 0 0 6.15E+07 4.99E+07 - - - 7.1838 1 221125_WJC_METTL3_EV_vs_WT_F03.19732.19732.2 4.36E-09 16/28 K.GQPAIIDGELYNEVK.V sp|Q9Y266|NUDC_HUMAN 1 1644.8359 1.95 34724 19732 2 1644.839097 823.4252 Nuclear migration protein nudC OS=Homo sapiens OX=9606 GN=NUDC PE=1 SV=1 4.14 3276.6 - 801586 - - - 1.9424 - 3.084 0.635 - 703.6 1 2 0 0.0032 15 0 0 0 2.04E+08 1.05E+08 - - - 6.499 0.9991 221125_WJC_METTL3_EV_vs_WT_F03.19733.19733.3 0.00774 13/52 R.IMEAIELYR[166.11]EETAK[136.11].M sp|Q9UNX4|WDR3_HUMAN 1 1712.8774 0.87 34725 19733 3 1712.880123 571.9664 WD repeat-containing protein 3 OS=Homo sapiens OX=9606 GN=WDR3 PE=1 SV=1 4.49 3276.7 - 789641 - - - 1.5938 - 2.426 0.366 - 181.3 1 2 1 0.0027 14 0 0 0 6.60E+06 7.58E+06 - - - 4.975 1 221125_WJC_METTL3_EV_vs_WT_F03.19734.19734.2 2.71E-07 14/24 K.LTFSC[160.03]LGGSDNFK[136.11].H "sp|Q15185|TEBP_HUMAN,tr|A0A087WYT3|A0A087WYT3_HUMAN" 2 1452.6799 1.13 34726 19734 2 1452.667538 727.3472 Prostaglandin E synthase 3 OS=Homo sapiens OX=9606 GN=PTGES3 PE=1 SV=1 5.83 3276.8 - 782913 - - - -8.4864 - 2.689 0.621 - 489 1 2 0 -0.0123 13 0 0 0 2.51E+07 2.22E+07 - - - 6.1626 0.9996 221125_WJC_METTL3_EV_vs_WT_F03.19735.19735.3 0.0111 13/48 R.LIHQTNLILQTFK.T "sp|Q9BUL8|PDC10_HUMAN,tr|C9J363|C9J363_HUMAN" 2 1567.9086 1.48 34727 19735 3 1567.912127 523.6435 Programmed cell death protein 10 OS=Homo sapiens OX=9606 GN=PDCD10 PE=1 SV=1 8.76 3276.9 - 733907 - - - 2.2412 - 2.608 0.321 - 204.2 1 2 0 0.0035 13 0 0 0 3.99E+06 2.70E+06 - - - 4.7169 0.9972 221125_WJC_METTL3_EV_vs_WT_F03.19736.19736.2 0.00436 20-Oct R.ELDELK[136.11]PWIEK[136.11].T sp|O43395|PRPF3_HUMAN 1 1414.7679 2.03 34728 19736 2 1414.774149 708.3912 U4\U6 small nuclear ribonucleoprotein Prp3 OS=Homo sapiens OX=9606 GN=PRPF3 PE=1 SV=2 4.41 3277.1 - 706995 - - - 4.4297 - 2.048 0.41 - 332.7 1 2 0 0.0063 11 0 0 0 1.19E+07 5.83E+06 - - - 4.0066 0.9999 221125_WJC_METTL3_EV_vs_WT_F03.19737.19737.3 3.01E-06 19/72 K.GVTIIGPATVGGIK[136.11]PGC[160.03]FK[136.11].L sp|P53396|ACLY_HUMAN 1 1887.0623 0.68 34729 19737 3 1887.064986 630.028 ATP-citrate synthase OS=Homo sapiens OX=9606 GN=ACLY PE=1 SV=3 9.31 3277.2 - 649173 - - - 1.4287 - 2.844 0.461 - 492.1 1 2 0 0.0027 19 0 0 0 9.20E+06 1.35E+07 - - - 6.2468 1 221125_WJC_METTL3_EV_vs_WT_F03.19739.19739.3 9.47E-09 17/56 R.GLLKPGLNVVLEGPK.K "sp|Q99848|EBP2_HUMAN,tr|H7C2Q8|H7C2Q8_HUMAN" 2 1532.929 1.33 34731 19739 3 1532.927565 511.9836 Probable rRNA-processing protein EBP2 OS=Homo sapiens OX=9606 GN=EBNA1BP2 PE=1 SV=2 8.59 3277.4 - 552806 - - - -0.9452 - 2.868 0.578 - 310.5 1 2 0 -0.0014 15 0 0 0 2.42E+06 1.83E+06 - - - 7.733 0.9998 221125_WJC_METTL3_EV_vs_WT_F03.19740.19740.2 4.39E-08 Dec-32 R.TYVTPPGTGFLPGDTAR[166.11].H "sp|Q9NPF4|OSGEP_HUMAN,tr|G3V445|G3V445_HUMAN" 2 1758.8816 0.79 34732 19740 2 1758.884189 880.4481 Probable tRNA N6-adenosine threonylcarbamoyltransferase OS=Homo sapiens OX=9606 GN=OSGEP PE=1 SV=1 5.5 3277.6 - 535590 - - - 1.4606 - 2.339 0.54 - 216.3 1 2 0 0.0026 17 0 0 0 5.21E+06 6.59E+06 - - - 5.1177 0.9963 221125_WJC_METTL3_EV_vs_WT_F03.19744.19744.3 1.57E-07 25/64 L.R[166.11]IINEPTAAAIAYGLDR[166.11].T "sp|P0DMV8|HS71A_HUMAN,sp|P0DMV9|HS71B_HUMAN,sp|P17066|HSP76_HUMAN,tr|A0A0G2JIW1|A0A0G2JIW1_HUMAN" 4 1863.0117 0.29 34735 19744 3 1863.015446 622.0112 Heat shock 70 kDa protein 1A OS=Homo sapiens OX=9606 GN=HSPA1A PE=1 SV=1 6.07 3278.1 - 865584 - - - 1.9914 - 4.14 0.453 - 1163.1 1 1 0 0.0037 17 0 0 0 1.28E+06 4.48E+06 - - - 7.1786 0.9994 221125_WJC_METTL3_EV_vs_WT_F03.19745.19745.2 0.00202 14/24 K.EQLTPSQIMSLEK[136.11].E "sp|Q00059|TFAM_HUMAN,tr|H7BYN3|H7BYN3_HUMAN" 2 1510.7792 0.74 34736 19745 2 1510.78302 756.3969 "Transcription factor A, mitochondrial OS=Homo sapiens OX=9606 GN=TFAM PE=1 SV=1" 4.53 3278.2 - 819659 - - - 2.4987 - 2.312 0.418 - 463 1 2 0 0.0038 13 0 0 0 5.07E+06 6.82E+06 - - - 4.2782 1 221125_WJC_METTL3_EV_vs_WT_F03.19746.19746.2 3.89E-09 16/30 K.TITLEVEPSDTIENVK[136.11].A "sp|P62979|RS27A_HUMAN,sp|P0CG48|UBC_HUMAN,sp|P0CG47|UBB_HUMAN,sp|P62987|RL40_HUMAN,tr|F5H388|F5H388_HUMAN,tr|F5GYU3|F5GYU3_HUMAN,tr|B4DV12|B4DV12_HUMAN,tr|J3QSA3|J3QSA3_HUMAN,tr|Q5PY61|Q5PY61_HUMAN,tr|F5H2Z3|F5H2Z3_HUMAN,tr|J3QS39|J3QS39_HUMAN,tr|J3QTR3|J3QTR3_HUMAN,tr|Q96C32|Q96C32_HUMAN,tr|M0R1V7|M0R1V7_HUMAN,tr|F5H747|F5H747_HUMAN,tr|F5H747|F5H747_HUMAN,tr|F5GXK7|F5GXK7_HUMAN,tr|F5GXK7|F5GXK7_HUMAN,tr|F5H6Q2|F5H6Q2_HUMAN,tr|F5GZ39|F5GZ39_HUMAN,tr|J3QKN0|J3QKN0_HUMAN,tr|J3QKN0|J3QKN0_HUMAN,tr|J3QKN0|J3QKN0_HUMAN,tr|F5H265|F5H265_HUMAN" 24 1794.9342 0.69 34737 19746 2 1794.9331 898.4744 Ubiquitin-40S ribosomal protein S27a OS=Homo sapiens OX=9606 GN=RPS27A PE=1 SV=2 4 3278.2 - 5.13E+07 - - - -0.6268 - 3.394 0.609 - 759.1 1 2 0 -0.0011 16 0 0 0 1.18E+09 1.71E+09 - - - 6.5431 0.9958 221125_WJC_METTL3_EV_vs_WT_F03.19747.19747.3 0.00551 13/60 K.TITLEVEPSDTIENVK[136.11].A "sp|P62979|RS27A_HUMAN,sp|P0CG48|UBC_HUMAN,sp|P0CG47|UBB_HUMAN,sp|P62987|RL40_HUMAN,tr|F5H388|F5H388_HUMAN,tr|F5GYU3|F5GYU3_HUMAN,tr|B4DV12|B4DV12_HUMAN,tr|J3QSA3|J3QSA3_HUMAN,tr|Q5PY61|Q5PY61_HUMAN,tr|F5H2Z3|F5H2Z3_HUMAN,tr|J3QS39|J3QS39_HUMAN,tr|J3QTR3|J3QTR3_HUMAN,tr|Q96C32|Q96C32_HUMAN,tr|M0R1V7|M0R1V7_HUMAN,tr|F5H747|F5H747_HUMAN,tr|F5H747|F5H747_HUMAN,tr|F5GXK7|F5GXK7_HUMAN,tr|F5GXK7|F5GXK7_HUMAN,tr|F5H6Q2|F5H6Q2_HUMAN,tr|F5GZ39|F5GZ39_HUMAN,tr|J3QKN0|J3QKN0_HUMAN,tr|J3QKN0|J3QKN0_HUMAN,tr|J3QKN0|J3QKN0_HUMAN,tr|F5H265|F5H265_HUMAN" 24 1794.9342 0.66 34738 19747 3 1795.936233 599.3187 Ubiquitin-40S ribosomal protein S27a OS=Homo sapiens OX=9606 GN=RPS27A PE=1 SV=2 4 3278.3 - 1.46E+07 - - - 558.2422 - 2.405 0.381 - 156.7 1 2 0 1.002 16 0 0 0 2.44E+08 3.67E+08 - - - 4.7619 0.9999 221125_WJC_METTL3_EV_vs_WT_F03.19748.19748.2 0.000263 15/24 K.DIELVMSQANVSR[166.11].A "sp|E9PAV3|NACAM_HUMAN,sp|Q13765|NACA_HUMAN,tr|A0A7I2V473|A0A7I2V473_HUMAN,tr|F8VZJ2|F8VZJ2_HUMAN,tr|A0A7I2V2K5|A0A7I2V2K5_HUMAN,tr|F8W0W4|F8W0W4_HUMAN,tr|H0YHX9|H0YHX9_HUMAN" 7 1470.7376 0.5 34739 19748 2 1470.737978 736.3761 "Nascent polypeptide-associated complex subunit alpha, muscle-specific form OS=Homo sapiens OX=9606 GN=NACA PE=1 SV=1" 4.37 3278.3 - 5.65E+06 - - - 0.2584 - 2.887 0.505 - 978.8 1 2 0 0.0004 13 0 0 0 6.99E+07 1.39E+08 - - - 5.4919 0.9999 221125_WJC_METTL3_EV_vs_WT_F03.19749.19749.2 1.53E-05 13/26 K.GLAITFVSDENDAK.L "sp|Q13838|DX39B_HUMAN,sp|O00148|DX39A_HUMAN,tr|H0Y400|H0Y400_HUMAN,tr|A0A0G2JJZ9|A0A0G2JJZ9_HUMAN" 4 1478.7253 1.17 34740 19749 2 1478.725044 740.3699 Spliceosome RNA helicase DDX39B OS=Homo sapiens OX=9606 GN=DDX39B PE=1 SV=1 4.03 3278.4 - 4.73E+06 - - - -0.1657 - 2.837 0.532 - 509.4 1 2 0 -0.0002 14 0 0 0 1.79E+08 1.53E+08 - - - 5.587 0.9999 221125_WJC_METTL3_EV_vs_WT_F03.19752.19752.2 0.000319 15/24 K.DIELVMSQANVSR.A "sp|E9PAV3|NACAM_HUMAN,sp|Q13765|NACA_HUMAN,tr|A0A7I2V473|A0A7I2V473_HUMAN,tr|F8VZJ2|F8VZJ2_HUMAN,tr|A0A7I2V2K5|A0A7I2V2K5_HUMAN,tr|F8W0W4|F8W0W4_HUMAN,tr|H0YHX9|H0YHX9_HUMAN" 7 1460.7293 0.5 34743 19752 2 1460.73112 731.3719 "Nascent polypeptide-associated complex subunit alpha, muscle-specific form OS=Homo sapiens OX=9606 GN=NACA PE=1 SV=1" 4.37 3278.5 - 2.46E+06 - - - 1.2268 - 2.862 0.515 - 981.8 1 2 0 0.0018 13 0 0 0 6.89E+07 1.39E+08 - - - 5.543 1 221125_WJC_METTL3_EV_vs_WT_F03.19753.19753.2 6.48E-12 17/32 K.NDSVVAGGGAIEMELSK.Y sp|Q99832|TCPH_HUMAN 1 1675.8087 0.19 34744 19753 2 1675.807108 838.9116 T-complex protein 1 subunit eta OS=Homo sapiens OX=9606 GN=CCT7 PE=1 SV=2 4.14 3278.6 - 2.24E+06 - - - -0.9506 - 3.344 0.707 - 649.9 1 2 0 -0.0016 17 0 0 0 3.74E+07 1.99E+08 - - - 7.2303 1 221125_WJC_METTL3_EV_vs_WT_F03.19754.19754.3 1.31E-11 20/56 K.IHTEPQLSAALEYVR.S "sp|P47897|SYQ_HUMAN,tr|A0A0U1RQL2|A0A0U1RQL2_HUMAN,tr|A0A0U1RRI9|A0A0U1RRI9_HUMAN,tr|A0A0U1RQT0|A0A0U1RQT0_HUMAN,tr|A0A1B0GVU9|A0A1B0GVU9_HUMAN,tr|A0A0U1RQE9|A0A0U1RQE9_HUMAN,tr|A0A0U1RQM8|A0A0U1RQM8_HUMAN,tr|A0A0U1RQU2|A0A0U1RQU2_HUMAN" 8 1725.905 1.43 34745 19754 3 1725.906455 576.3089 Glutamine--tRNA ligase OS=Homo sapiens OX=9606 GN=QARS1 PE=1 SV=1 5.4 3278.7 - 1.63E+06 - - - 0.8523 - 3.989 0.528 - 1000 1 2 0 0.0015 15 0 0 0 1.80E+07 1.26E+07 - - - 8.0364 0.998 221125_WJC_METTL3_EV_vs_WT_F03.19756.19756.3 0.0408 Dec-44 R.LK[136.11]LPAVVTADLR[166.11].L "sp|P38117|ETFB_HUMAN,tr|M0QY67|M0QY67_HUMAN" 2 1312.8197 1.73 34747 19756 3 1312.820928 438.6139 Electron transfer flavoprotein subunit beta OS=Homo sapiens OX=9606 GN=ETFB PE=1 SV=3 8.75 3278.9 - 1.50E+06 - - - 0.9034 - 2.273 0.282 - 186.1 1 2 1 0.0012 12 0 0 0 4.91E+07 2.85E+07 - - - 3.9597 0.9997 221125_WJC_METTL3_EV_vs_WT_F03.19757.19757.3 0.00104 Dec-44 K.EFWEQK[136.11]PLLIQR[166.11].D "sp|Q8IUF8|RIOX2_HUMAN,tr|D6RCB6|D6RCB6_HUMAN" 2 1603.8841 0.78 34748 19757 3 1603.883091 535.6353 Ribosomal oxygenase 2 OS=Homo sapiens OX=9606 GN=RIOX2 PE=1 SV=1 6.24 3279 - 1.71E+06 - - - -0.6497 - 2.004 0.341 - 170.8 1 2 0 -0.001 12 0 0 0 8.71E+06 1.12E+07 - - - 4.2684 1 221125_WJC_METTL3_EV_vs_WT_F03.19758.19758.2 6.13E-09 16/28 K.GYNDDYYEESYFTTR.T "sp|P50402|EMD_HUMAN,tr|A0A804HIV7|A0A804HIV7_HUMAN,tr|Q5HY57|Q5HY57_HUMAN" 3 1921.7643 1.24 34749 19758 2 1921.765882 961.8894 Emerin OS=Homo sapiens OX=9606 GN=EMD PE=1 SV=1 3.92 3279.1 - 1.16E+06 - - - 0.8477 - 2.996 0.802 - 938.7 1 2 0 0.0016 15 0 0 0 1.63E+07 1.31E+07 - - - 7.6618 1 221125_WJC_METTL3_EV_vs_WT_F03.19760.19760.3 1.13E-06 17/56 K.GQPAIIDGELYNEVK.V sp|Q9Y266|NUDC_HUMAN 1 1644.8359 2.31 34751 19760 3 1644.838827 549.2859 Nuclear migration protein nudC OS=Homo sapiens OX=9606 GN=NUDC PE=1 SV=1 4.14 3279.4 - 791512 - - - 1.7783 - 2.616 0.525 - 333.4 1 2 0 0.0029 15 0 0 0 2.79E+07 1.21E+07 - - - 6.9017 1 221125_WJC_METTL3_EV_vs_WT_F03.19761.19761.2 4.77E-09 13/20 K.HLWDYTFGPEK.L "sp|P61160|ARP2_HUMAN,tr|F5H6T1|F5H6T1_HUMAN" 2 1391.651 0.4 34752 19761 2 1391.651337 696.8328 Actin-related protein 2 OS=Homo sapiens OX=9606 GN=ACTR2 PE=1 SV=1 5.32 3279.5 - 786170 - - - 0.2414 - 2.543 0.621 - 538.5 1 2 0 0.0003 11 0 0 0 5.11E+06 1.28E+07 - - - 6.1525 0.9998 221125_WJC_METTL3_EV_vs_WT_F03.19762.19762.3 0.275 13/52 R.IEPHTGLLLLSVQK.R sp|P15924|DESP_HUMAN 1 1546.9083 0.54 34753 19762 3 1546.907219 516.6434 Desmoplakin OS=Homo sapiens OX=9606 GN=DSP PE=1 SV=3 6.75 3279.6 - 671733 - - - -0.6852 - 2.473 0.326 - 264.1 1 2 0 -0.0011 14 0 0 0 3.05E+07 5.60E+07 - - - 4.5805 0.9308 221125_WJC_METTL3_EV_vs_WT_F03.19763.19763.2 0.175 30-Sep R.IQAQLALKPGLIGNAN.M sp|O43395|PRPF3_HUMAN 1 1619.9359 4.34 34754 19763 2 1619.936744 810.9752 U4\U6 small nuclear ribonucleoprotein Prp3 OS=Homo sapiens OX=9606 GN=PRPF3 PE=1 SV=2 8.75 3279.7 - 554988 - - - 0.5266 - 1.918 0.22 - 177.5 1 1 0 0.0009 16 0 0 0 2.48E+06 5.70E+05 - - - 2.2669 0.9997 221125_WJC_METTL3_EV_vs_WT_F03.19765.19765.3 0.0193 Nov-48 K.LLLWAQNELDQK[136.11]K[136.11].V sp|Q9NWU2|GID8_HUMAN 1 1613.9112 1.21 34755 19765 3 1613.91426 538.9777 Glucose-induced degradation protein 8 homolog OS=Homo sapiens OX=9606 GN=GID8 PE=1 SV=1 6.07 3280 - 448440 - - - 1.901 - 2.389 0.333 - 153.3 1 2 0 0.0031 13 0 0 0 2.74E+06 2.26E+06 - - - 4.613 0.9927 221125_WJC_METTL3_EV_vs_WT_F03.19769.19769.2 0.419 24-Aug R.LQQSFPGIEVTVK.A sp|O75792|RNH2A_HUMAN 1 1444.7926 2.46 34759 19769 2 1444.790224 723.4036 Ribonuclease H2 subunit A OS=Homo sapiens OX=9606 GN=RNASEH2A PE=1 SV=2 6 3280.2 - 4.43E+06 - - - -1.6307 - 1.282 0.207 - 109.3 1 2 0 -0.0024 13 0 0 0 1.08E+08 4.40E+07 - - - 1.2067 1 221125_WJC_METTL3_EV_vs_WT_F03.19770.19770.3 3.43E-06 14/56 K.VIIVDAENVLVADK[136.11]R[166.11].L "sp|Q8NDZ4|DIK2A_HUMAN,tr|E7ET39|E7ET39_HUMAN,tr|C9JY09|C9JY09_HUMAN" 3 1670.9686 1.11 34760 19770 3 1670.968987 557.9968 Divergent protein kinase domain 2A OS=Homo sapiens OX=9606 GN=DIPK2A PE=1 SV=1 4.56 3280.3 - 2.27E+06 - - - 0.237 - 2.435 0.485 - 193.4 1 2 0 0.0004 15 0 0 0 2.31E+07 2.08E+07 - - - 6.2694 1 221125_WJC_METTL3_EV_vs_WT_F03.19772.19772.2 4.20E-12 16/28 K.GYNDDYYEESYFTTR[166.11].T "sp|P50402|EMD_HUMAN,tr|A0A804HIV7|A0A804HIV7_HUMAN,tr|Q5HY57|Q5HY57_HUMAN" 3 1931.7725 1.24 34762 19772 2 1931.772044 966.8935 Emerin OS=Homo sapiens OX=9606 GN=EMD PE=1 SV=1 3.92 3280.5 - 1.68E+06 - - - -0.248 - 3.002 0.78 - 924.9 1 2 0 -0.0005 15 0 0 0 1.63E+07 1.31E+07 - - - 7.5046 1 221125_WJC_METTL3_EV_vs_WT_F03.19773.19773.3 9.35E-09 15/56 K.IHTEPQLSAALEYVR[166.11].S "sp|P47897|SYQ_HUMAN,tr|A0A0U1RQL2|A0A0U1RQL2_HUMAN,tr|A0A0U1RRI9|A0A0U1RRI9_HUMAN,tr|A0A0U1RQT0|A0A0U1RQT0_HUMAN,tr|A0A1B0GVU9|A0A1B0GVU9_HUMAN,tr|A0A0U1RQE9|A0A0U1RQE9_HUMAN,tr|A0A0U1RQM8|A0A0U1RQM8_HUMAN,tr|A0A0U1RQU2|A0A0U1RQU2_HUMAN" 8 1735.9133 1.57 34763 19773 3 1735.911656 579.645 Glutamine--tRNA ligase OS=Homo sapiens OX=9606 GN=QARS1 PE=1 SV=1 5.4 3280.6 - 1.55E+06 - - - -0.9206 - 3.171 0.555 - 349.1 1 2 0 -0.0016 15 0 0 0 2.02E+07 1.29E+07 - - - 7.7386 0.9996 221125_WJC_METTL3_EV_vs_WT_F03.19774.19774.2 9.29E-05 24-Oct K.FGNEVIPVTVTVK[136.11].G "sp|P24752|THIL_HUMAN,tr|A0A5F9ZHJ7|A0A5F9ZHJ7_HUMAN,tr|A0A5F9ZHD4|A0A5F9ZHD4_HUMAN,tr|A0A5F9ZHJ0|A0A5F9ZHJ0_HUMAN,tr|A0A5F9ZHL1|A0A5F9ZHL1_HUMAN,tr|A0A5F9ZI66|A0A5F9ZI66_HUMAN" 6 1409.801 1.34 34764 19774 2 1409.802327 705.9078 "Acetyl-CoA acetyltransferase, mitochondrial OS=Homo sapiens OX=9606 GN=ACAT1 PE=1 SV=1" 6 3280.7 - 1.17E+06 - - - 0.9647 - 1.928 0.386 - 226.3 1 2 0 0.0014 13 0 0 0 9.06E+06 6.77E+06 - - - 3.5765 1 221125_WJC_METTL3_EV_vs_WT_F03.19775.19775.2 2.89E-09 20/36 R.LEGMLSQSVSSQYNMAGVR.T "sp|P54105|ICLN_HUMAN,tr|J3KN38|J3KN38_HUMAN,tr|E9PMI6|E9PMI6_HUMAN" 3 2055.9718 3.43 34765 19775 2 2055.969085 1028.9932 Methylosome subunit pICln OS=Homo sapiens OX=9606 GN=CLNS1A PE=1 SV=1 6 3280.8 - 1.14E+06 - - - -1.3011 - 3.952 0.618 - 1276.2 1 2 0 -0.0027 19 0 0 0 8.16E+06 2.38E+06 - - - 6.9833 0.9999 221125_WJC_METTL3_EV_vs_WT_F03.19777.19777.2 5.05E-06 14/22 K.TSIAIDTIINQK.R "sp|P25705|ATPA_HUMAN,tr|K7EK77|K7EK77_HUMAN,tr|K7ENJ4|K7ENJ4_HUMAN" 3 1315.7347 1.36 34767 19777 2 1315.733983 658.8746 "ATP synthase subunit alpha, mitochondrial OS=Homo sapiens OX=9606 GN=ATP5F1A PE=1 SV=1" 5.5 3281 - 951700 - - - -0.5685 - 2.759 0.501 - 952.2 1 2 0 -0.0007 12 0 0 0 2.28E+08 1.68E+08 - - - 5.4114 1 221125_WJC_METTL3_EV_vs_WT_F03.19778.19778.2 2.44E-08 14/22 K.TSIAIDTIINQK[136.11].R "sp|P25705|ATPA_HUMAN,tr|K7EK77|K7EK77_HUMAN,tr|K7ENJ4|K7ENJ4_HUMAN" 3 1323.7489 1.36 34768 19778 2 1323.745395 662.8817 "ATP synthase subunit alpha, mitochondrial OS=Homo sapiens OX=9606 GN=ATP5F1A PE=1 SV=1" 5.5 3281.1 - 917385 - - - -2.6712 - 2.885 0.531 - 960 1 2 0 -0.0035 12 0 0 0 2.28E+08 1.67E+08 - - - 5.7496 0.9998 221125_WJC_METTL3_EV_vs_WT_F03.19779.19779.3 0.00106 13/72 K.GVTIIGPATVGGIKPGC[160.03]FK.L sp|P53396|ACLY_HUMAN 1 1871.0339 0.68 34769 19779 3 1871.030628 624.6852 ATP-citrate synthase OS=Homo sapiens OX=9606 GN=ACLY PE=1 SV=3 9.31 3281.2 - 792992 - - - -1.7434 - 2.467 0.366 - 159.1 1 2 0 -0.0033 19 0 0 0 9.20E+06 1.35E+07 - - - 4.8381 1 221125_WJC_METTL3_EV_vs_WT_F03.19784.19784.3 0.000411 15/56 R.LLHDQVGVIQFGPYK[136.11].Q "sp|P53621|COPA_HUMAN,tr|A0A3B3ISC6|A0A3B3ISC6_HUMAN,tr|A0A3B3IS84|A0A3B3IS84_HUMAN,tr|A0A3B3ITI7|A0A3B3ITI7_HUMAN" 4 1720.9392 0.22 34772 19784 3 1720.939139 574.6537 Coatomer subunit alpha OS=Homo sapiens OX=9606 GN=COPA PE=1 SV=2 6.74 3281.9 - 3.39E+06 - - - -0.0308 - 3.192 0.463 - 437.2 1 2 0 -0.0001 15 0 0 0 1.05E+07 4.78E+07 - - - 6.7305 1 221125_WJC_METTL3_EV_vs_WT_F03.19788.19788.3 5.73E-12 16/56 R.LSFQHDPETSVLVLR[166.11].K "sp|Q14697|GANAB_HUMAN,tr|E9PKU7|E9PKU7_HUMAN,tr|F5H6X6|F5H6X6_HUMAN" 3 1749.9289 0.8 34776 19788 3 1749.926771 584.3169 Neutral alpha-glucosidase AB OS=Homo sapiens OX=9606 GN=GANAB PE=1 SV=3 5.32 3282.2 - 2.21E+06 - - - -1.2189 - 3.115 0.619 - 391.9 1 2 0 -0.0021 15 0 0 0 1.90E+07 2.37E+07 - - - 8.4055 1 221125_WJC_METTL3_EV_vs_WT_F03.19792.19792.2 8.16E-09 17/30 R.LVSALSEASTFEDPQR.L "sp|Q96NU1|SAM11_HUMAN,tr|A0A087WYW1|A0A087WYW1_HUMAN,tr|A0A087WX24|A0A087WX24_HUMAN,tr|A0A087X223|A0A087X223_HUMAN,tr|H7BY14|H7BY14_HUMAN,tr|A0A087WXB3|A0A087WXB3_HUMAN,tr|H7C3J6|H7C3J6_HUMAN,tr|A0A087WYU3|A0A087WYU3_HUMAN,tr|A0A087WU74|A0A087WU74_HUMAN" 9 1748.8581 0.72 34780 19792 2 1748.856532 875.4363 Sterile alpha motif domain-containing protein 11 OS=Homo sapiens OX=9606 GN=SAMD11 PE=1 SV=3 4.14 3282.6 - 828416 - - - -0.8932 - 2.898 0.642 - 686.7 1 2 0 -0.0016 16 0 0 0 5.95E+06 8.25E+06 - - - 6.3983 0.9996 221125_WJC_METTL3_EV_vs_WT_F03.19793.19793.2 0.000545 28-Oct R.FTLLPPTSPGDTAPK[136.11].Y "sp|Q13724|MOGS_HUMAN,tr|A0A3B3IS52|A0A3B3IS52_HUMAN,tr|A0A3B3IRK6|A0A3B3IRK6_HUMAN,tr|C9JDQ1|C9JDQ1_HUMAN,tr|A0A3B3ITC1|A0A3B3ITC1_HUMAN" 5 1548.8279 1.16 34781 19793 2 1548.826722 775.4212 Mannosyl-oligosaccharide glucosidase OS=Homo sapiens OX=9606 GN=MOGS PE=1 SV=5 5.84 3282.8 - 810543 - - - -0.767 - 1.722 0.416 - 196.8 1 2 0 -0.0012 15 0 0 0 1.26E+07 1.09E+07 - - - 3.4494 1 221125_WJC_METTL3_EV_vs_WT_F03.19795.19795.3 0.000462 16/56 R.LLHDQVGVIQFGPYK.Q "sp|P53621|COPA_HUMAN,tr|A0A3B3ISC6|A0A3B3ISC6_HUMAN,tr|A0A3B3IS84|A0A3B3IS84_HUMAN,tr|A0A3B3ITI7|A0A3B3ITI7_HUMAN" 4 1712.925 0.22 34783 19795 3 1712.924221 571.9823 Coatomer subunit alpha OS=Homo sapiens OX=9606 GN=COPA PE=1 SV=2 6.74 3283 - 572378 - - - -0.4501 - 2.875 0.447 - 471.1 1 2 0 -0.0008 15 0 0 0 1.05E+07 4.80E+07 - - - 6.279 0.9987 221125_WJC_METTL3_EV_vs_WT_F03.19796.19796.3 0.00111 Dec-40 R.DLFHGATFVPR[166.11].V sp|Q96DV4|RM38_HUMAN 1 1268.6541 1.12 34784 19796 3 1268.659194 423.892 "39S ribosomal protein L38, mitochondrial OS=Homo sapiens OX=9606 GN=MRPL38 PE=1 SV=2" 6.74 3283.1 - 553495 - - - 3.9948 - 1.868 0.396 - 135.1 1 2 0 0.0051 11 0 0 0 4.28E+06 3.84E+06 - - - 4.7287 0.9999 221125_WJC_METTL3_EV_vs_WT_F03.19800.19800.2 0.000106 14/22 K.DNIQAMVIVPTR.E "sp|P26196|DDX6_HUMAN,tr|Q8IV96|Q8IV96_HUMAN" 2 1355.7231 1.09 34786 19800 2 1355.723899 678.8688 Probable ATP-dependent RNA helicase DDX6 OS=Homo sapiens OX=9606 GN=DDX6 PE=1 SV=2 5.84 3283.5 - 4.33E+06 - - - 0.5739 - 2.806 0.524 - 813.4 1 2 0 0.0008 12 0 0 0 5.21E+07 4.77E+07 - - - 5.6258 1 221125_WJC_METTL3_EV_vs_WT_F03.19801.19801.3 6.12E-10 17/64 K.NDSVVAGGGAIEMELSK[136.11].Y sp|Q99832|TCPH_HUMAN 1 1683.8229 0.14 34787 19801 3 1683.822362 562.2816 T-complex protein 1 subunit eta OS=Homo sapiens OX=9606 GN=CCT7 PE=1 SV=2 4.14 3283.6 - 2.48E+06 - - - -0.3201 - 3.316 0.608 - 469.3 1 2 0 -0.0005 17 0 0 0 3.41E+06 2.39E+07 - - - 8.3469 0.9995 221125_WJC_METTL3_EV_vs_WT_F03.19805.19805.3 0.0785 14/56 R.YR[166.11]VPDVLVADPPIAR[166.11].L "sp|Q14697|GANAB_HUMAN,tr|F5H6X6|F5H6X6_HUMAN" 2 1699.9524 0.98 34791 19805 3 1699.953114 567.6581 Neutral alpha-glucosidase AB OS=Homo sapiens OX=9606 GN=GANAB PE=1 SV=3 5.96 3283.8 - 1.38E+06 - - - 0.4018 - 2.165 0.403 - 178.7 1 2 1 0.0007 15 0 0 0 1.66E+07 1.69E+07 - - - 5.0484 1 221125_WJC_METTL3_EV_vs_WT_F03.19806.19806.3 4.95E-05 16/56 K.IEAINQAIANEYEVR.R "sp|Q8NCA5|FA98A_HUMAN,tr|E9PH82|E9PH82_HUMAN" 2 1731.8792 1.38 34792 19806 3 1731.880901 578.3003 Protein FAM98A OS=Homo sapiens OX=9606 GN=FAM98A PE=1 SV=2 4.25 3283.9 - 1.36E+06 - - - 1.003 - 2.978 0.472 - 231.3 1 2 0 0.0017 15 0 0 0 3.67E+07 2.67E+07 - - - 6.6493 0.9364 221125_WJC_METTL3_EV_vs_WT_F03.19807.19807.2 3.09 28-Sep R.FTLLPPTSPGDTAPK.Y "sp|Q13724|MOGS_HUMAN,tr|A0A3B3IS52|A0A3B3IS52_HUMAN,tr|A0A3B3IRK6|A0A3B3IRK6_HUMAN,tr|C9JDQ1|C9JDQ1_HUMAN,tr|A0A3B3ITC1|A0A3B3ITC1_HUMAN" 5 1540.8137 1.07 34793 19807 2 1540.810627 771.4141 Mannosyl-oligosaccharide glucosidase OS=Homo sapiens OX=9606 GN=MOGS PE=1 SV=5 5.84 3284 - 1.17E+06 - - - -2.0009 - 1.247 0.059 - 170.9 2 2 0 -0.0031 15 0 0 0 1.64E+07 1.54E+07 - - - -0.116 0.9999 221125_WJC_METTL3_EV_vs_WT_F03.19808.19808.2 1.42E-06 15/26 R.SEVLAEESIVC[160.03]LQK[136.11].A "sp|O43663|PRC1_HUMAN,tr|H0YLA0|H0YLA0_HUMAN,tr|H0YM42|H0YM42_HUMAN" 3 1611.8269 0.21 34794 19808 2 1611.826952 806.9207 Protein regulator of cytokinesis 1 OS=Homo sapiens OX=9606 GN=PRC1 PE=1 SV=2 4.25 3284.2 - 931175 - - - 0.0174 - 2.553 0.529 - 384.1 1 2 0 0 14 0 0 0 1.42E+06 6.66E+06 - - - 5.3002 1 221125_WJC_METTL3_EV_vs_WT_F03.19809.19809.2 3.56E-08 16/28 K.IEAINQAIANEYEVR.R "sp|Q8NCA5|FA98A_HUMAN,tr|E9PH82|E9PH82_HUMAN" 2 1731.8792 8.8 34795 19809 2 1731.877754 866.9469 Protein FAM98A OS=Homo sapiens OX=9606 GN=FAM98A PE=1 SV=2 4.25 3284.3 - 819528 - - - -0.8141 - 3.409 0.622 - 928.4 1 2 0 -0.0014 15 0 0 0 2.50E+07 2.85E+06 - - - 6.6499 0.9999 221125_WJC_METTL3_EV_vs_WT_F03.19810.19810.3 1.12E-05 13/44 K.TSIAIDTIINQK[136.11].R "sp|P25705|ATPA_HUMAN,tr|K7EK77|K7EK77_HUMAN,tr|K7ENJ4|K7ENJ4_HUMAN" 3 1323.7489 1.11 34796 19810 3 1323.75158 442.2569 "ATP synthase subunit alpha, mitochondrial OS=Homo sapiens OX=9606 GN=ATP5F1A PE=1 SV=1" 5.5 3284.4 - 677398 - - - 2.0011 - 2.342 0.425 - 341.5 1 2 0 0.0026 12 0 0 0 1.43E+07 1.28E+07 - - - 5.6365 0.9901 221125_WJC_METTL3_EV_vs_WT_F03.19811.19811.3 1 Jul-32 R.NWTIHTWIR[166.11].Q "sp|Q92552|RT27_HUMAN,tr|G5EA06|G5EA06_HUMAN,tr|D6RH20|D6RH20_HUMAN,tr|D6RJC7|D6RJC7_HUMAN" 4 1235.6439 0.82 34797 19811 3 1235.642372 412.8886 "28S ribosomal protein S27, mitochondrial OS=Homo sapiens OX=9606 GN=MRPS27 PE=1 SV=3" 9.76 3284.6 - 603194 - - - -1.2334 - 1.604 0.172 - 101.3 1 2 0 -0.0015 9 0 0 0 3.02E+06 3.68E+06 - - - 1.8812 0.9996 221125_WJC_METTL3_EV_vs_WT_F03.19813.19813.3 0.067 Dec-40 K.LDKDIVALMTR.R "sp|Q02880|TOP2B_HUMAN,tr|E9PCY5|E9PCY5_HUMAN" 2 1273.7064 0.5 34799 19813 3 1273.704535 425.5761 DNA topoisomerase 2-beta OS=Homo sapiens OX=9606 GN=TOP2B PE=1 SV=3 5.96 3284.8 - 529923 - - - -1.4705 - 2.678 0.387 - 305.5 1 2 1 -0.0019 11 0 0 0 6.27E+06 1.24E+07 - - - 5.6526 0.9993 221125_WJC_METTL3_EV_vs_WT_F03.19814.19814.3 0.00801 Dec-48 R.LQQSFPGIEVTVK.A sp|O75792|RNH2A_HUMAN 1 1444.7926 2.25 34800 19814 3 1444.794961 482.6048 Ribonuclease H2 subunit A OS=Homo sapiens OX=9606 GN=RNASEH2A PE=1 SV=2 6 3284.9 - 528711 - - - 1.648 - 2.044 0.303 - 155.4 1 2 0 0.0024 13 0 0 0 5.86E+06 2.60E+06 - - - 3.8558 1 221125_WJC_METTL3_EV_vs_WT_F03.19816.19816.2 1.41E-07 13/26 K.GLAITFVSDENDAK[136.11].L "sp|Q13838|DX39B_HUMAN,sp|O00148|DX39A_HUMAN,tr|H0Y400|H0Y400_HUMAN,tr|A0A0G2JJZ9|A0A0G2JJZ9_HUMAN" 4 1486.7395 1.17 34801 19816 2 1486.737559 744.377 Spliceosome RNA helicase DDX39B OS=Homo sapiens OX=9606 GN=DDX39B PE=1 SV=1 4.03 3285.1 - 9.98E+06 - - - -1.2981 - 2.739 0.591 - 529.7 1 2 0 -0.0019 14 0 0 0 1.78E+08 1.52E+08 - - - 5.934 1 221125_WJC_METTL3_EV_vs_WT_F03.19818.19818.2 2.03E-05 20-Dec K.NALESYAFNMK[136.11].S "sp|P0DMV8|HS71A_HUMAN,sp|P34931|HS71L_HUMAN,sp|P0DMV9|HS71B_HUMAN,tr|Q53FA3|Q53FA3_HUMAN,tr|V9GZ37|V9GZ37_HUMAN,tr|A0A0G2JIW1|A0A0G2JIW1_HUMAN" 6 1294.6107 0.2 34802 19818 2 1294.610027 648.3126 Heat shock 70 kDa protein 1A OS=Homo sapiens OX=9606 GN=HSPA1A PE=1 SV=1 6 3285.4 - 9.16E+06 - - - -0.5376 - 2.557 0.572 - 602.2 1 2 0 -0.0007 11 0 0 0 9.24E+07 4.69E+08 - - - 5.8053 1 221125_WJC_METTL3_EV_vs_WT_F03.19819.19819.2 2.71E-12 20/30 K.LSLDGQNIYNAC[160.03]C[160.03]TLR.L "sp|P26599|PTBP1_HUMAN,tr|A0A6Q8PEX4|A0A6Q8PEX4_HUMAN,tr|A0A0U1RRM4|A0A0U1RRM4_HUMAN,tr|A6NLN1|A6NLN1_HUMAN,tr|A0A087WU68|A0A087WU68_HUMAN,tr|A0A7I2V4H6|A0A7I2V4H6_HUMAN,tr|A0A7I2V621|A0A7I2V621_HUMAN,tr|K7EK45|K7EK45_HUMAN" 8 1896.8822 0.93 34803 19819 2 1896.880672 949.4484 Polypyrimidine tract-binding protein 1 OS=Homo sapiens OX=9606 GN=PTBP1 PE=1 SV=1 5.82 3285.5 - 2.64E+06 - - - -0.8145 - 3.841 0.596 - 1159.6 1 2 0 -0.0015 16 0 0 0 4.46E+07 4.80E+07 - - - 6.7511 1 221125_WJC_METTL3_EV_vs_WT_F03.19820.19820.2 1.68E-10 17/30 K.LSLDGQNIYNAC[160.03]C[160.03]TLR[166.11].L "sp|P26599|PTBP1_HUMAN,tr|A0A6Q8PEX4|A0A6Q8PEX4_HUMAN,tr|A0A0U1RRM4|A0A0U1RRM4_HUMAN,tr|A6NLN1|A6NLN1_HUMAN,tr|A0A087WU68|A0A087WU68_HUMAN,tr|A0A7I2V4H6|A0A7I2V4H6_HUMAN,tr|A0A7I2V621|A0A7I2V621_HUMAN,tr|K7EK45|K7EK45_HUMAN" 8 1906.8905 0.93 34804 19820 2 1906.886965 954.4525 Polypyrimidine tract-binding protein 1 OS=Homo sapiens OX=9606 GN=PTBP1 PE=1 SV=1 5.82 3285.6 - 2.99E+06 - - - -1.847 - 3.486 0.613 - 740.1 1 2 0 -0.0035 16 0 0 0 4.46E+07 4.80E+07 - - - 6.6376 1 221125_WJC_METTL3_EV_vs_WT_F03.19821.19821.3 5.69E-05 14/52 R.SLESLHSFVAAATK.E "sp|Q15149|PLEC_HUMAN,tr|E9PMV1|E9PMV1_HUMAN,tr|H0YDN1|H0YDN1_HUMAN" 3 1459.7671 0.7 34805 19821 3 1459.766428 487.5963 Plectin OS=Homo sapiens OX=9606 GN=PLEC PE=1 SV=3 6.47 3285.6 - 2.16E+06 - - - -0.4562 - 2.778 0.489 - 135.3 1 2 0 -0.0007 14 0 0 0 1.76E+07 2.52E+07 - - - 6.707 1 221125_WJC_METTL3_EV_vs_WT_F03.19822.19822.3 2.03E-06 16/60 K.LSLDGQNIYNAC[160.03]C[160.03]TLR[166.11].L "sp|P26599|PTBP1_HUMAN,tr|A0A6Q8PEX4|A0A6Q8PEX4_HUMAN,tr|A0A0U1RRM4|A0A0U1RRM4_HUMAN,tr|A6NLN1|A6NLN1_HUMAN,tr|A0A087WU68|A0A087WU68_HUMAN,tr|A0A7I2V4H6|A0A7I2V4H6_HUMAN,tr|A0A7I2V621|A0A7I2V621_HUMAN,tr|K7EK45|K7EK45_HUMAN" 8 1906.8905 0.97 34806 19822 3 1906.889353 636.6374 Polypyrimidine tract-binding protein 1 OS=Homo sapiens OX=9606 GN=PTBP1 PE=1 SV=1 5.82 3285.8 - 1.65E+06 - - - -0.5947 - 3.156 0.574 - 204.7 1 2 0 -0.0011 16 0 0 0 2.77E+07 2.85E+07 - - - 7.8882 1 221125_WJC_METTL3_EV_vs_WT_F03.19823.19823.3 8.40E-06 15/60 K.LSLDGQNIYNAC[160.03]C[160.03]TLR.L "sp|P26599|PTBP1_HUMAN,tr|A0A6Q8PEX4|A0A6Q8PEX4_HUMAN,tr|A0A0U1RRM4|A0A0U1RRM4_HUMAN,tr|A6NLN1|A6NLN1_HUMAN,tr|A0A087WU68|A0A087WU68_HUMAN,tr|A0A7I2V4H6|A0A7I2V4H6_HUMAN,tr|A0A7I2V621|A0A7I2V621_HUMAN,tr|K7EK45|K7EK45_HUMAN" 8 1896.8822 0.97 34807 19823 3 1896.880063 633.3013 Polypyrimidine tract-binding protein 1 OS=Homo sapiens OX=9606 GN=PTBP1 PE=1 SV=1 5.82 3285.8 - 1.52E+06 - - - -1.1355 - 2.72 0.597 - 269.2 1 2 0 -0.0022 16 0 0 0 2.77E+07 2.85E+07 - - - 7.7628 0.9993 221125_WJC_METTL3_EV_vs_WT_F03.19826.19826.3 0.00881 14/52 R.GSIPVFWSQRPNLK.Y "sp|Q9NTJ5|SAC1_HUMAN,tr|E9PGZ4|E9PGZ4_HUMAN,tr|A0A5F9ZHN7|A0A5F9ZHN7_HUMAN,tr|F8WDN7|F8WDN7_HUMAN" 4 1627.8835 1.8 34810 19826 3 1627.883388 543.6351 Phosphatidylinositol-3-phosphatase SAC1 OS=Homo sapiens OX=9606 GN=SACM1L PE=1 SV=2 11 3286.2 - 1.16E+06 - - - -0.0448 - 2.288 0.254 - 233.9 1 2 0 -0.0001 14 0 0 0 9.72E+06 5.39E+06 - - - 3.5714 0.9995 221125_WJC_METTL3_EV_vs_WT_F03.19828.19828.2 0.0431 24-Dec R.AQLLQPTLEINPR.H "sp|Q12931|TRAP1_HUMAN,tr|I3L0K7|I3L0K7_HUMAN" 2 1491.8409 2.18 34812 19828 2 1491.837897 746.9277 "Heat shock protein 75 kDa, mitochondrial OS=Homo sapiens OX=9606 GN=TRAP1 PE=1 SV=3" 6.05 3286.4 - 821885 - - - -2.0317 - 2.464 0.342 - 443.6 1 2 0 -0.003 13 0 0 0 1.38E+08 6.33E+07 - - - 3.8805 0.9996 221125_WJC_METTL3_EV_vs_WT_F03.19833.19833.2 5.22E-08 16/28 K.EAMVQAEEAAAEITR[166.11].K "sp|O00567|NOP56_HUMAN,tr|A0A494C128|A0A494C128_HUMAN,tr|H0YDU4|H0YDU4_HUMAN,tr|H0Y653|H0Y653_HUMAN" 4 1627.7751 0.46 34816 19833 2 1627.779993 814.8948 Nucleolar protein 56 OS=Homo sapiens OX=9606 GN=NOP56 PE=1 SV=4 4.09 3287 - 1.32E+06 - - - 3.0023 - 2.788 0.556 - 907.9 1 2 0 0.0049 15 0 0 0 3.74E+06 8.09E+06 - - - 5.6669 0.9999 221125_WJC_METTL3_EV_vs_WT_F03.19836.19836.2 1.33E-07 14/22 K.LNDLEEALQQAK.E sp|P35908|K22E_HUMAN 1 1370.7042 999 34818 19836 2 1370.704947 686.3594 "Keratin, type II cytoskeletal 2 epidermal OS=Homo sapiens OX=9606 GN=KRT2 PE=1 SV=2" 4.14 3287.3 - 1.35E+07 - - - 0.5749 - 2.937 0.454 - 843.1 1 2 0 0.0008 12 0 0 0 2.27E+09 0.00E+00 - - - 5.2288 1 221125_WJC_METTL3_EV_vs_WT_F03.19838.19838.3 5.30E-05 17/60 R.TVNALEIELQAQHNLR.D "sp|Q15323|K1H1_HUMAN,sp|O76011|KRT34_HUMAN,sp|Q14525|KT33B_HUMAN,sp|O76009|KT33A_HUMAN,tr|A0A140TA62|A0A140TA62_HUMAN,tr|A0A140TA69|A0A140TA69_HUMAN" 6 1847.9854 999 34820 19838 3 1847.986139 617.0024 "Keratin, type I cuticular Ha1 OS=Homo sapiens OX=9606 GN=KRT31 PE=1 SV=3" 5.37 3287.4 - 3.17E+06 - - - 0.4215 - 3.086 0.486 - 266.6 1 2 0 0.0008 16 0 0 0 2.11E+07 0.00E+00 - - - 6.8496 0.9919 221125_WJC_METTL3_EV_vs_WT_F03.19839.19839.2 0.0138 22-Aug K.HTDESLGDC[160.03]SFL.N "sp|Q86U44|MTA70_HUMAN,tr|H0YFV6|H0YFV6_HUMAN" 2 1379.5663 - 34821 19839 2 1379.565702 690.7904 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 4.02 3287.4 - 2.50E+06 - - - -0.4661 - 2.101 0.5 - 102 1 1 0 -0.0006 12 0 0 0 - - - - - 4.6872 1 221125_WJC_METTL3_EV_vs_WT_F03.19840.19840.2 1.30E-12 19/28 K.APGMNTIDQGMAALK[136.11].L "sp|Q9Y5A9|YTHD2_HUMAN,tr|S4R3J8|S4R3J8_HUMAN,tr|S4R3V3|S4R3V3_HUMAN" 3 1524.752 1.39 34822 19840 2 1524.755461 763.3833 YTH domain-containing family protein 2 OS=Homo sapiens OX=9606 GN=YTHDF2 PE=1 SV=2 5.88 3287.5 - 2.37E+06 - - - 2.2804 - 4.207 0.674 - 1552.9 1 2 0 0.0035 15 0 0 0 3.91E+08 2.81E+08 - - - 7.5504 0.9999 221125_WJC_METTL3_EV_vs_WT_F03.19842.19842.2 1.57E-08 17/26 K.QPAIISQLDPVNER.M sp|Q08211|DHX9_HUMAN 1 1578.8366 1.03 34824 19842 2 1578.835924 790.4256 ATP-dependent RNA helicase A OS=Homo sapiens OX=9606 GN=DHX9 PE=1 SV=4 4.37 3287.7 - 1.52E+06 - - - -0.4092 - 2.249 0.57 - 651.4 1 2 0 -0.0006 14 0 0 0 7.21E+07 7.00E+07 - - - 5.2847 1 221125_WJC_METTL3_EV_vs_WT_F03.19844.19844.2 8.10E-09 15/24 R.AGSSESIAAFIQR.L "sp|P46379|BAG6_HUMAN,tr|A0A7I2V508|A0A7I2V508_HUMAN,tr|A0A7P0MQS5|A0A7P0MQS5_HUMAN,tr|A0A0G2JL47|A0A0G2JL47_HUMAN,tr|A0A024RCR6|A0A024RCR6_HUMAN,tr|A0A0G2JK23|A0A0G2JK23_HUMAN" 6 1335.6783 1.38 34826 19844 2 1335.677916 668.8464 Large proline-rich protein BAG6 OS=Homo sapiens OX=9606 GN=BAG6 PE=1 SV=2 6.05 3287.9 - 1.30E+06 - - - -0.2718 - 2.956 0.544 - 724 1 2 0 -0.0004 13 0 0 0 5.78E+07 4.19E+07 - - - 5.8406 1 221125_WJC_METTL3_EV_vs_WT_F03.19845.19845.3 6.00E-11 17/56 K.EAMVQAEEAAAEITR.K "sp|O00567|NOP56_HUMAN,tr|A0A494C128|A0A494C128_HUMAN,tr|H0YDU4|H0YDU4_HUMAN,tr|H0Y653|H0Y653_HUMAN" 4 1617.7668 1.92 34827 19845 3 1617.766814 540.2629 Nucleolar protein 56 OS=Homo sapiens OX=9606 GN=NOP56 PE=1 SV=4 4.09 3288 - 1.28E+06 - - - -0.0136 - 3.075 0.652 - 494.5 1 2 0 0 15 0 0 0 1.57E+07 8.20E+06 - - - 8.7403 1 221125_WJC_METTL3_EV_vs_WT_F03.19847.19847.3 2.64E-06 14/36 R.R[166.11]APFDLFENR[166.11].K sp|P07900|HS90A_HUMAN 1 1283.6526 0.46 34829 19847 3 1283.652721 428.8915 Heat shock protein HSP 90-alpha OS=Homo sapiens OX=9606 GN=HSP90AA1 PE=1 SV=5 6.07 3288.2 - 1.26E+06 - - - 0.1254 - 2.75 0.505 - 337.9 1 2 0 0.0002 10 0 0 0 4.42E+06 9.52E+06 - - - 7.1245 0.9998 221125_WJC_METTL3_EV_vs_WT_F03.19848.19848.3 1.22E-05 14/44 R.FVIEENLHC[160.03]IIK[136.11].S sp|Q09161|NCBP1_HUMAN 1 1521.8105 1.05 34830 19848 3 1521.81727 508.2774 Nuclear cap-binding protein subunit 1 OS=Homo sapiens OX=9606 GN=NCBP1 PE=1 SV=1 5.4 3288.3 - 1.22E+06 - - - 4.4578 - 2.75 0.502 - 138.7 1 2 0 0.0068 12 0 0 0 2.78E+07 2.64E+07 - - - 6.9389 0.9987 221125_WJC_METTL3_EV_vs_WT_F03.19849.19849.2 0.017 24-Dec K.ELNQVMEQLGDAR.L "sp|Q14683|SMC1A_HUMAN,tr|G8JLG1|G8JLG1_HUMAN,tr|A0A6Q8PHC3|A0A6Q8PHC3_HUMAN" 3 1501.7195 1.04 34831 19849 2 1501.721472 751.867 Structural maintenance of chromosomes protein 1A OS=Homo sapiens OX=9606 GN=SMC1A PE=1 SV=2 4.14 3288.4 - 1.18E+06 - - - 1.3185 - 1.474 0.34 - 237.8 1 2 0 0.002 13 0 0 0 1.69E+07 1.63E+07 - - - 2.5474 0.9999 221125_WJC_METTL3_EV_vs_WT_F03.19852.19852.3 1.93E-05 14/52 K.LVINTEEVFR[166.11]PYAK[136.11].H sp|P78527|PRKDC_HUMAN 1 1695.9315 3.41 34834 19852 3 1695.934332 566.3178 DNA-dependent protein kinase catalytic subunit OS=Homo sapiens OX=9606 GN=PRKDC PE=1 SV=3 6.14 3288.6 - 1.01E+06 - - - 1.6834 - 2.629 0.451 - 228.2 1 2 0 0.0029 14 0 0 0 6.45E+07 1.89E+07 - - - 6.1362 1 221125_WJC_METTL3_EV_vs_WT_F03.19853.19853.3 5.72E-07 13/44 K.AYFHLLNQIAPK[136.11].G "sp|P13797|PLST_HUMAN,sp|Q14651|PLSI_HUMAN,tr|A0A0A0MSQ0|A0A0A0MSQ0_HUMAN,tr|C9JAM8|C9JAM8_HUMAN,tr|H7C4N2|H7C4N2_HUMAN" 5 1421.7911 0.5 34835 19853 3 1421.789391 474.9376 Plastin-3 OS=Homo sapiens OX=9606 GN=PLS3 PE=1 SV=4 8.64 3288.8 - 929272 - - - -1.1816 - 2.501 0.445 - 191.4 1 2 0 -0.0017 12 0 0 0 2.38E+07 4.74E+07 - - - 6.0418 1 221125_WJC_METTL3_EV_vs_WT_F03.19854.19854.2 3.53E-08 17/28 K.EAMVQAEEAAAEITR.K "sp|O00567|NOP56_HUMAN,tr|A0A494C128|A0A494C128_HUMAN,tr|H0YDU4|H0YDU4_HUMAN,tr|H0Y653|H0Y653_HUMAN" 4 1617.7668 0.64 34836 19854 2 1617.763655 809.8907 Nucleolar protein 56 OS=Homo sapiens OX=9606 GN=NOP56 PE=1 SV=4 4.09 3288.9 - 916988 - - - -1.9663 - 3.501 0.659 - 1222.8 1 2 0 -0.0032 15 0 0 0 1.18E+07 1.83E+07 - - - 6.9881 0.9999 221125_WJC_METTL3_EV_vs_WT_F03.19856.19856.2 1.94E-06 13/28 K.GQPAIIDGELYNEVK[136.11].V sp|Q9Y266|NUDC_HUMAN 1 1652.8501 1.94 34837 19856 2 1652.849196 827.4323 Nuclear migration protein nudC OS=Homo sapiens OX=9606 GN=NUDC PE=1 SV=1 4.14 3289.1 - 3.72E+06 - - - -0.5481 - 2.693 0.557 - 340.2 1 2 0 -0.0009 15 0 0 0 2.04E+08 1.05E+08 - - - 5.5903 1 221125_WJC_METTL3_EV_vs_WT_F03.19857.19857.3 0.000109 15/44 K.LNDLEEALQQAK.E sp|P35908|K22E_HUMAN 1 1370.7042 254.8 34838 19857 3 1370.702989 457.9087 "Keratin, type II cytoskeletal 2 epidermal OS=Homo sapiens OX=9606 GN=KRT2 PE=1 SV=2" 4.14 3289.2 - 7.94E+06 - - - -0.8536 - 2.784 0.443 - 449 1 2 0 -0.0012 12 0 0 0 2.37E+08 9.30E+05 - - - 6.3168 1 221125_WJC_METTL3_EV_vs_WT_F03.19860.19860.2 3.87E-13 22/32 R.SLGYAYVNFQQPADAER.A "sp|Q13310|PABP4_HUMAN,sp|P11940|PABP1_HUMAN,tr|A0A7I2V649|A0A7I2V649_HUMAN,tr|B1ANR0|B1ANR0_HUMAN,tr|A0A7I2V4L7|A0A7I2V4L7_HUMAN,tr|E5RHG7|E5RHG7_HUMAN,tr|B1ANR1|B1ANR1_HUMAN,tr|H0YAR2|H0YAR2_HUMAN,tr|E7ERJ7|E7ERJ7_HUMAN,tr|E5RJB9|E5RJB9_HUMAN,tr|A0A7I2YQ88|A0A7I2YQ88_HUMAN,tr|E5RH24|E5RH24_HUMAN,tr|H0YBN4|H0YBN4_HUMAN,tr|E5RGH3|E5RGH3_HUMAN,tr|A0A087WTT1|A0A087WTT1_HUMAN,tr|A0A7I2YQ90|A0A7I2YQ90_HUMAN,tr|E7EQV3|E7EQV3_HUMAN" 17 1927.9064 1.43 34841 19860 2 1927.906882 964.9605 Polyadenylate-binding protein 4 OS=Homo sapiens OX=9606 GN=PABPC4 PE=1 SV=1 4.37 3289.4 - 2.31E+06 - - - 0.2287 - 3.84 0.694 - 1548.9 1 2 0 0.0004 17 0 0 0 3.96E+08 2.77E+08 - - - 7.4747 0.9956 221125_WJC_METTL3_EV_vs_WT_F03.19861.19861.3 2.00E-08 13/64 V.LEDTENWLYEDGEDQPK[136.11].Q "sp|O95757|HS74L_HUMAN,sp|P34932|HSP74_HUMAN,tr|E9PDE8|E9PDE8_HUMAN,tr|A0A087WYC1|A0A087WYC1_HUMAN" 4 2087.9051 0.12 34842 19861 3 2087.89938 696.9756 Heat shock 70 kDa protein 4L OS=Homo sapiens OX=9606 GN=HSPA4L PE=1 SV=3 3.66 3289.5 - 2.16E+06 - - - -2.7444 - 2.454 0.616 - 219.5 1 1 0 -0.0057 17 0 0 0 4.77E+06 4.10E+07 - - - 7.6741 1 221125_WJC_METTL3_EV_vs_WT_F03.19862.19862.2 4.62E-12 18/32 K.NDSVVAGGGAIEMELSK[136.11].Y sp|Q99832|TCPH_HUMAN 1 1683.8229 0.19 34843 19862 2 1683.825094 842.9187 T-complex protein 1 subunit eta OS=Homo sapiens OX=9606 GN=CCT7 PE=1 SV=2 4.14 3289.6 - 2.13E+06 - - - 1.3024 - 3.254 0.68 - 824.9 1 2 0 0.0022 17 0 0 0 3.74E+07 1.99E+08 - - - 6.9636 1 221125_WJC_METTL3_EV_vs_WT_F03.19864.19864.2 1.02E-08 19/32 R.SLGYAYVNFQQPADAER[166.11].A "sp|Q13310|PABP4_HUMAN,sp|P11940|PABP1_HUMAN,tr|A0A7I2V649|A0A7I2V649_HUMAN,tr|B1ANR0|B1ANR0_HUMAN,tr|A0A7I2V4L7|A0A7I2V4L7_HUMAN,tr|E5RHG7|E5RHG7_HUMAN,tr|B1ANR1|B1ANR1_HUMAN,tr|H0YAR2|H0YAR2_HUMAN,tr|E7ERJ7|E7ERJ7_HUMAN,tr|E5RJB9|E5RJB9_HUMAN,tr|A0A7I2YQ88|A0A7I2YQ88_HUMAN,tr|E5RH24|E5RH24_HUMAN,tr|H0YBN4|H0YBN4_HUMAN,tr|E5RGH3|E5RGH3_HUMAN,tr|A0A087WTT1|A0A087WTT1_HUMAN,tr|A0A7I2YQ90|A0A7I2YQ90_HUMAN,tr|E7EQV3|E7EQV3_HUMAN" 17 1937.9147 1.43 34845 19864 2 1937.91951 969.9646 Polyadenylate-binding protein 4 OS=Homo sapiens OX=9606 GN=PABPC4 PE=1 SV=1 4.37 3289.8 - 1.85E+06 - - - 2.4764 - 3.351 0.653 - 1101.5 1 2 0 0.0048 17 0 0 0 3.96E+08 2.77E+08 - - - 6.8356 0.9998 221125_WJC_METTL3_EV_vs_WT_F03.19865.19865.3 4.28E-06 14/44 R.ETEILFHSSLLR[166.11].L "sp|Q9H6R4|NOL6_HUMAN,tr|A0A0A0MRW6|A0A0A0MRW6_HUMAN" 2 1453.7804 1.13 34846 19865 3 1453.77671 485.6008 Nucleolar protein 6 OS=Homo sapiens OX=9606 GN=NOL6 PE=1 SV=2 5.4 3289.9 - 1.75E+06 - - - -2.5719 - 2.676 0.362 - 428.1 1 2 0 -0.0037 12 0 0 0 1.70E+07 1.50E+07 - - - 5.3033 0.9999 221125_WJC_METTL3_EV_vs_WT_F03.19866.19866.3 2.63E-05 Nov-36 R.DSGYLHLLYK.R "sp|P35658|NU214_HUMAN,tr|A0A0A0MSW3|A0A0A0MSW3_HUMAN,tr|A0A494BZU9|A0A494BZU9_HUMAN,tr|A0A494C1F2|A0A494C1F2_HUMAN" 4 1207.6237 1.83 34847 19866 3 1207.622099 403.5485 Nuclear pore complex protein Nup214 OS=Homo sapiens OX=9606 GN=NUP214 PE=1 SV=2 6.74 3290 - 1.51E+06 - - - -1.3456 - 2.211 0.464 - 207.5 1 2 0 -0.0016 10 0 0 0 1.01E+08 5.52E+07 - - - 6.0299 0.999 221125_WJC_METTL3_EV_vs_WT_F03.19867.19867.3 6.76E-10 17/72 R.PVTVEPMDQLDDEEGLPEK[136.11].L "sp|Q15233|NONO_HUMAN,tr|A0A7I2V535|A0A7I2V535_HUMAN,tr|A0A7I2V4N2|A0A7I2V4N2_HUMAN,tr|A0A7I2V4K9|A0A7I2V4K9_HUMAN,tr|A0A7I2V464|A0A7I2V464_HUMAN,tr|A0A7P0MRW0|A0A7P0MRW0_HUMAN,tr|H7C367|H7C367_HUMAN,tr|A0A7I2V4J2|A0A7I2V4J2_HUMAN,tr|A0A7I2V5Y7|A0A7I2V5Y7_HUMAN" 9 2148.0024 0.76 34848 19867 3 2148.001635 717.0081 Non-POU domain-containing octamer-binding protein OS=Homo sapiens OX=9606 GN=NONO PE=1 SV=4 3.66 3290.1 - 1.35E+06 - - - -0.3473 - 3.31 0.612 - 276.4 1 1 0 -0.0007 19 0 0 0 1.71E+07 2.25E+07 - - - 8.3037 1 221125_WJC_METTL3_EV_vs_WT_F03.19868.19868.3 6.58E-07 14/56 K.EAMVQAEEAAAEITR[166.11].K "sp|O00567|NOP56_HUMAN,tr|A0A494C128|A0A494C128_HUMAN,tr|H0YDU4|H0YDU4_HUMAN,tr|H0Y653|H0Y653_HUMAN" 4 1627.7751 1.88 34849 19868 3 1627.775603 543.599 Nucleolar protein 56 OS=Homo sapiens OX=9606 GN=NOP56 PE=1 SV=4 4.09 3290.2 - 1.02E+06 - - - 0.3053 - 2.83 0.527 - 356 1 2 0 0.0005 15 0 0 0 1.52E+07 8.10E+06 - - - 7.1299 1 221125_WJC_METTL3_EV_vs_WT_F03.19869.19869.3 8.79E-05 Nov-36 R.DSGYLHLLYK[136.11].R "sp|P35658|NU214_HUMAN,tr|A0A0A0MSW3|A0A0A0MSW3_HUMAN,tr|A0A494BZU9|A0A494BZU9_HUMAN,tr|A0A494C1F2|A0A494C1F2_HUMAN" 4 1215.6379 1.83 34850 19869 3 1215.638231 406.2199 Nuclear pore complex protein Nup214 OS=Homo sapiens OX=9606 GN=NUP214 PE=1 SV=2 6.74 3290.4 - 748548 - - - 0.2525 - 2.213 0.505 - 204 1 2 0 0.0003 10 0 0 0 1.01E+08 5.52E+07 - - - 6.49 0.9867 221125_WJC_METTL3_EV_vs_WT_F03.19870.19870.2 1.18E-05 28-Sep R.YEEELEINDFPQTAR[166.11].W "sp|Q7L014|DDX46_HUMAN,tr|A0A0C4DG89|A0A0C4DG89_HUMAN" 2 1862.8562 1.16 34851 19870 2 1863.85765 932.4354 Probable ATP-dependent RNA helicase DDX46 OS=Homo sapiens OX=9606 GN=DDX46 PE=1 SV=2 3.91 3290.5 - 717970 - - - 537.5922 - 1.637 0.508 - 141.1 1 2 0 1.0015 15 0 0 0 6.30E+06 5.42E+06 - - - 3.6904 0.9983 221125_WJC_METTL3_EV_vs_WT_F03.19877.19877.3 0.0227 Nov-44 R.ASVAFHTQLFFK.S "sp|Q9Y2L1|RRP44_HUMAN,tr|G3V1J5|G3V1J5_HUMAN" 2 1394.7347 1.21 34856 19877 3 1394.734614 465.9188 Exosome complex exonuclease RRP44 OS=Homo sapiens OX=9606 GN=DIS3 PE=1 SV=2 8.8 3291.3 - 2.71E+06 - - - -0.0416 - 2.209 0.199 - 149.3 1 2 0 -0.0001 12 0 0 0 3.54E+07 2.93E+07 - - - 2.9554 0.9991 221125_WJC_METTL3_EV_vs_WT_F03.19878.19878.2 0.0168 14-Aug R.VDEIIWVK[136.11].T sp|Q86U44|MTA70_HUMAN 1 1008.5735 0.03 34857 19878 2 1008.572065 505.294 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 4.37 3291.4 - 1.96E+07 - - - -1.4555 - 1.897 0.25 - 218.1 1 2 0 -0.0015 8 0 0 0 2.28E+07 8.04E+08 - - - 2.8181 0.9998 221125_WJC_METTL3_EV_vs_WT_F03.19879.19879.3 0.0021 14/52 K.QPAIISQLDPVNER[166.11].M sp|Q08211|DHX9_HUMAN 1 1588.8448 0.76 34858 19879 3 1588.843924 530.6222 ATP-dependent RNA helicase A OS=Homo sapiens OX=9606 GN=DHX9 PE=1 SV=4 4.37 3291.4 - 2.54E+06 - - - -0.5765 - 2.212 0.342 - 217 1 2 0 -0.0009 14 0 0 0 3.76E+07 4.96E+07 - - - 4.4625 1 221125_WJC_METTL3_EV_vs_WT_F03.19880.19880.3 7.09E-07 15/48 R.AQLLQPTLEINPR.H "sp|Q12931|TRAP1_HUMAN,tr|I3L0K7|I3L0K7_HUMAN" 2 1491.8409 2.58 34859 19880 3 1491.839834 498.2876 "Heat shock protein 75 kDa, mitochondrial OS=Homo sapiens OX=9606 GN=TRAP1 PE=1 SV=3" 6.05 3291.5 - 2.52E+06 - - - -0.7333 - 2.629 0.516 - 447 1 2 0 -0.0011 13 0 0 0 3.60E+07 1.39E+07 - - - 6.9133 0.9999 221125_WJC_METTL3_EV_vs_WT_F03.19881.19881.3 9.62E-05 13/44 R.ETEILFHSSLLR.L "sp|Q9H6R4|NOL6_HUMAN,tr|A0A0A0MRW6|A0A0A0MRW6_HUMAN" 2 1443.7722 1.09 34860 19881 3 1443.771918 482.2647 Nucleolar protein 6 OS=Homo sapiens OX=9606 GN=NOL6 PE=1 SV=2 5.4 3291.6 - 1.64E+06 - - - -0.1808 - 2.392 0.386 - 346.6 1 2 0 -0.0003 12 0 0 0 1.62E+07 1.49E+07 - - - 5.2609 0.9999 221125_WJC_METTL3_EV_vs_WT_F03.19883.19883.3 0.00663 18/48 R.ALYYLQIHPQELR[166.11].Q "sp|Q16531|DDB1_HUMAN,tr|A0A7P0TAK7|A0A7P0TAK7_HUMAN,tr|A0A7P0T870|A0A7P0T870_HUMAN,tr|A0A7P0TB30|A0A7P0TB30_HUMAN,tr|A0A7P0Z3Z5|A0A7P0Z3Z5_HUMAN,tr|F5GY55|F5GY55_HUMAN,tr|A0A7P0Z4B9|A0A7P0Z4B9_HUMAN" 7 1652.8914 0.83 34862 19883 3 1652.894635 551.9711 DNA damage-binding protein 1 OS=Homo sapiens OX=9606 GN=DDB1 PE=1 SV=1 6.79 3291.8 - 1.40E+06 - - - 1.959 - 2.652 0.393 - 358.8 1 2 0 0.0032 13 0 0 0 1.42E+07 1.71E+07 - - - 5.565 0.9999 221125_WJC_METTL3_EV_vs_WT_F03.19885.19885.3 5.06E-05 13/48 R.AGSSESIAAFIQR.L "sp|P46379|BAG6_HUMAN,tr|A0A7I2V508|A0A7I2V508_HUMAN,tr|A0A7P0MQS5|A0A7P0MQS5_HUMAN,tr|A0A0G2JL47|A0A0G2JL47_HUMAN,tr|A0A024RCR6|A0A024RCR6_HUMAN,tr|A0A0G2JK23|A0A0G2JK23_HUMAN" 6 1335.6783 2.2 34864 19885 3 1335.676479 446.2334 Large proline-rich protein BAG6 OS=Homo sapiens OX=9606 GN=BAG6 PE=1 SV=2 6.05 3292.1 - 1.04E+06 - - - -1.3476 - 1.996 0.426 - 97.8 1 2 0 -0.0018 13 0 0 0 9.46E+06 4.29E+06 - - - 5.1629 1 221125_WJC_METTL3_EV_vs_WT_F03.19889.19889.3 7.18E-08 17/64 R.SLGYAYVNFQQPADAER.A "sp|Q13310|PABP4_HUMAN,sp|P11940|PABP1_HUMAN,tr|A0A7I2V649|A0A7I2V649_HUMAN,tr|B1ANR0|B1ANR0_HUMAN,tr|A0A7I2V4L7|A0A7I2V4L7_HUMAN,tr|E5RHG7|E5RHG7_HUMAN,tr|B1ANR1|B1ANR1_HUMAN,tr|H0YAR2|H0YAR2_HUMAN,tr|E7ERJ7|E7ERJ7_HUMAN,tr|E5RJB9|E5RJB9_HUMAN,tr|A0A7I2YQ88|A0A7I2YQ88_HUMAN,tr|E5RH24|E5RH24_HUMAN,tr|H0YBN4|H0YBN4_HUMAN,tr|E5RGH3|E5RGH3_HUMAN,tr|A0A087WTT1|A0A087WTT1_HUMAN,tr|A0A7I2YQ90|A0A7I2YQ90_HUMAN,tr|E7EQV3|E7EQV3_HUMAN" 17 1927.9064 1.45 34866 19889 3 1927.906447 643.6428 Polyadenylate-binding protein 4 OS=Homo sapiens OX=9606 GN=PABPC4 PE=1 SV=1 4.37 3292.6 - 1.19E+07 - - - 0.0031 - 3.066 0.564 - 317.6 1 2 0 0 17 0 0 0 2.66E+08 1.84E+08 - - - 7.6584 1 221125_WJC_METTL3_EV_vs_WT_F03.19892.19892.3 6.89E-07 18/52 K.RVESPVLPPVLVPR.H "sp|Q99717|SMAD5_HUMAN,sp|Q15797|SMAD1_HUMAN" 2 1556.9402 1.42 34869 19892 3 1556.93824 519.9874 Mothers against decapentaplegic homolog 5 OS=Homo sapiens OX=9606 GN=SMAD5 PE=1 SV=1 9.6 3292.8 - 2.44E+06 - - - -1.2897 - 3.233 0.526 - 676 1 2 0 -0.002 14 0 0 0 6.75E+07 4.77E+07 - - - 7.5222 0.9999 221125_WJC_METTL3_EV_vs_WT_F03.19893.19893.3 0.000435 Nov-44 R.ASVAFHTQLFFK[136.11].S "sp|Q9Y2L1|RRP44_HUMAN,tr|G3V1J5|G3V1J5_HUMAN" 2 1402.7489 1.31 34870 19893 3 1402.747494 468.5902 Exosome complex exonuclease RRP44 OS=Homo sapiens OX=9606 GN=DIS3 PE=1 SV=2 8.8 3292.8 - 1.87E+06 - - - -0.9824 - 2.383 0.384 - 132.4 1 2 0 -0.0014 12 0 0 0 3.55E+07 2.70E+07 - - - 5.2278 1 221125_WJC_METTL3_EV_vs_WT_F03.19895.19895.3 1.73E-06 13/56 R.K[136.11]FGYVDFESAEDLEK[136.11].A "sp|P19338|NUCL_HUMAN,tr|A0A7I2V506|A0A7I2V506_HUMAN,tr|A0A7I2V699|A0A7I2V699_HUMAN,tr|A0A7I2V2U7|A0A7I2V2U7_HUMAN,tr|A0A7I2V3F3|A0A7I2V3F3_HUMAN,tr|A0A7I2V428|A0A7I2V428_HUMAN,tr|A0A7I2V349|A0A7I2V349_HUMAN,tr|H7BY16|H7BY16_HUMAN,tr|A0A7I2V5M5|A0A7I2V5M5_HUMAN,tr|A0A7I2V2S8|A0A7I2V2S8_HUMAN,tr|C9JLB1|C9JLB1_HUMAN" 11 1791.8538 1.08 34872 19895 3 1791.854586 598.2919 Nucleolin OS=Homo sapiens OX=9606 GN=NCL PE=1 SV=3 4.18 3293 - 1.63E+06 - - - 0.4403 - 2.768 0.561 - 248.9 1 2 0 0.0008 15 0 0 0 3.78E+07 3.50E+07 - - - 7.451 0.9999 221125_WJC_METTL3_EV_vs_WT_F03.19898.19898.3 0.00161 16/48 K.TDK[136.11]VFEVMLATDR[166.11].S "sp|P22061|PIMT_HUMAN,tr|F6S8N6|F6S8N6_HUMAN,tr|F8WAV5|F8WAV5_HUMAN,tr|A0A0A0MRJ6|A0A0A0MRJ6_HUMAN,tr|F8WDT3|F8WDT3_HUMAN,tr|F8WAX2|F8WAX2_HUMAN" 6 1541.7878 0.74 34875 19898 3 1541.786826 514.9366 Protein-L-isoaspartate(D-aspartate) O-methyltransferase OS=Homo sapiens OX=9606 GN=PCMT1 PE=1 SV=4 4.56 3293.3 - 1.22E+06 - - - -0.6635 - 3.14 0.43 - 451.3 1 2 1 -0.001 13 0 0 0 8.24E+06 1.12E+07 - - - 6.4361 0.9999 221125_WJC_METTL3_EV_vs_WT_F03.19899.19899.2 9.64E-07 13/24 K.QIMENAEINNIIK[136.11].L "sp|P11388|TOP2A_HUMAN,sp|Q02880|TOP2B_HUMAN,tr|E9PCY5|E9PCY5_HUMAN" 3 1536.8061 0.41 34876 19899 2 1536.804515 769.4103 DNA topoisomerase 2-alpha OS=Homo sapiens OX=9606 GN=TOP2A PE=1 SV=3 4.53 3293.5 - 946020 - - - -1.0496 - 2.637 0.466 - 487.8 1 2 0 -0.0016 13 0 0 0 6.81E+06 1.67E+07 - - - 4.971 1 221125_WJC_METTL3_EV_vs_WT_F03.19900.19900.3 1.27E-08 17/44 K.AYFHLLNQIAPK.G "sp|P13797|PLST_HUMAN,sp|Q14651|PLSI_HUMAN,tr|A0A0A0MSQ0|A0A0A0MSQ0_HUMAN,tr|C9JAM8|C9JAM8_HUMAN,tr|H7C4N2|H7C4N2_HUMAN" 5 1413.7769 0.51 34877 19900 3 1413.775727 472.2662 Plastin-3 OS=Homo sapiens OX=9606 GN=PLS3 PE=1 SV=4 8.64 3293.6 - 930137 - - - -0.8092 - 2.949 0.542 - 352.7 1 2 0 -0.0011 12 0 0 0 2.36E+07 4.67E+07 - - - 7.5801 1 221125_WJC_METTL3_EV_vs_WT_F03.19902.19902.3 1.54E-05 19/56 K.LGAVYDVSHYNALLK[136.11].V "sp|P42704|LPPRC_HUMAN,tr|A0A804HI14|A0A804HI14_HUMAN,tr|A0A804HL40|A0A804HL40_HUMAN,tr|A0A804HKJ0|A0A804HKJ0_HUMAN,tr|A0A804HKR3|A0A804HKR3_HUMAN,tr|A0A0C4DG06|A0A0C4DG06_HUMAN,tr|A0A804HIN4|A0A804HIN4_HUMAN,tr|A0A804HLG8|A0A804HLG8_HUMAN,tr|A0A804HIV5|A0A804HIV5_HUMAN,tr|A0A804HHY9|A0A804HHY9_HUMAN,tr|A0A804HJH8|A0A804HJH8_HUMAN,tr|B8ZZ38|B8ZZ38_HUMAN,tr|A0A804HI40|A0A804HI40_HUMAN,tr|A0A804HJZ1|A0A804HJZ1_HUMAN,tr|C9JCA9|C9JCA9_HUMAN,tr|A0A804HIQ7|A0A804HIQ7_HUMAN,tr|A0A804HK30|A0A804HK30_HUMAN,tr|A0A804HKI2|A0A804HKI2_HUMAN,tr|A0A804HKR5|A0A804HKR5_HUMAN,tr|A0A804HKX0|A0A804HKX0_HUMAN,tr|A0A804HIG4|A0A804HIG4_HUMAN,tr|A0A804HK02|A0A804HK02_HUMAN" 22 1669.8919 0.58 34879 19902 3 1669.895306 557.6379 "Leucine-rich PPR motif-containing protein, mitochondrial OS=Homo sapiens OX=9606 GN=LRPPRC PE=1 SV=3" 6.74 3293.8 - 750175 - - - 2.0355 - 3.695 0.461 - 561.6 1 2 0 0.0034 15 0 0 0 1.55E+07 2.65E+07 - - - 7.0891 1 221125_WJC_METTL3_EV_vs_WT_F03.19903.19903.3 2.82E-05 17/56 K.LGAVYDVSHYNALLK.V "sp|P42704|LPPRC_HUMAN,tr|A0A804HI14|A0A804HI14_HUMAN,tr|A0A804HL40|A0A804HL40_HUMAN,tr|A0A804HKJ0|A0A804HKJ0_HUMAN,tr|A0A804HKR3|A0A804HKR3_HUMAN,tr|A0A0C4DG06|A0A0C4DG06_HUMAN,tr|A0A804HIN4|A0A804HIN4_HUMAN,tr|A0A804HLG8|A0A804HLG8_HUMAN,tr|A0A804HIV5|A0A804HIV5_HUMAN,tr|A0A804HHY9|A0A804HHY9_HUMAN,tr|A0A804HJH8|A0A804HJH8_HUMAN,tr|B8ZZ38|B8ZZ38_HUMAN,tr|A0A804HI40|A0A804HI40_HUMAN,tr|A0A804HJZ1|A0A804HJZ1_HUMAN,tr|C9JCA9|C9JCA9_HUMAN,tr|A0A804HIQ7|A0A804HIQ7_HUMAN,tr|A0A804HK30|A0A804HK30_HUMAN,tr|A0A804HKI2|A0A804HKI2_HUMAN,tr|A0A804HKR5|A0A804HKR5_HUMAN,tr|A0A804HKX0|A0A804HKX0_HUMAN,tr|A0A804HIG4|A0A804HIG4_HUMAN,tr|A0A804HK02|A0A804HK02_HUMAN" 22 1661.8777 0.6 34880 19903 3 1661.880075 554.9665 "Leucine-rich PPR motif-containing protein, mitochondrial OS=Homo sapiens OX=9606 GN=LRPPRC PE=1 SV=3" 6.74 3293.9 - 601792 - - - 1.4249 - 2.954 0.467 - 320.5 1 2 0 0.0024 15 0 0 0 1.58E+07 2.65E+07 - - - 6.5723 0.998 221125_WJC_METTL3_EV_vs_WT_F03.19905.19905.3 0.0418 Dec-68 K.LYDILGVPPGASENELK[136.11]K[136.11].A "sp|O60884|DNJA2_HUMAN,tr|I3L320|I3L320_HUMAN" 2 1958.0695 0.16 34881 19905 3 1958.068734 653.6971 DnaJ homolog subfamily A member 2 OS=Homo sapiens OX=9606 GN=DNAJA2 PE=1 SV=1 4.68 3294.2 - 1.11E+06 - - - -0.4137 - 2.031 0.227 - 97.5 1 2 0 -0.0008 18 0 0 0 3.17E+06 1.98E+07 - - - 2.8349 1 221125_WJC_METTL3_EV_vs_WT_F03.19907.19907.2 3.24E-07 13/22 K.DGVWNLQNEVTK.E sp|Q6P2Q9|PRP8_HUMAN 1 1401.6888 1.32 34882 19907 2 1401.687485 701.8517 Pre-mRNA-processing-splicing factor 8 OS=Homo sapiens OX=9606 GN=PRPF8 PE=1 SV=2 4.37 3294.4 - 3.44E+06 - - - -0.9695 - 2.577 0.647 - 540.1 1 2 0 -0.0014 12 0 0 0 4.10E+07 3.10E+07 - - - 6.31 1 221125_WJC_METTL3_EV_vs_WT_F03.19908.19908.3 6.61E-06 Oct-56 K.APGMNTIDQGMAALK[136.11].L "sp|Q9Y5A9|YTHD2_HUMAN,tr|S4R3J8|S4R3J8_HUMAN,tr|S4R3V3|S4R3V3_HUMAN" 3 1524.752 1.42 34883 19908 3 1524.752799 509.2579 YTH domain-containing family protein 2 OS=Homo sapiens OX=9606 GN=YTHDF2 PE=1 SV=2 5.88 3294.4 - 2.89E+06 - - - 0.5345 - 2.052 0.529 - 90.3 1 2 0 0.0008 15 0 0 0 4.74E+07 3.34E+07 - - - 6.3133 1 221125_WJC_METTL3_EV_vs_WT_F03.19910.19910.2 2.86E-07 16/32 V.LEDTENWLYEDGEDQPK[136.11].Q "sp|O95757|HS74L_HUMAN,sp|P34932|HSP74_HUMAN,tr|E9PDE8|E9PDE8_HUMAN,tr|A0A087WYC1|A0A087WYC1_HUMAN" 4 2087.9051 0.001 34885 19910 2 2087.90449 1044.9598 Heat shock 70 kDa protein 4L OS=Homo sapiens OX=9606 GN=HSPA4L PE=1 SV=3 3.66 3294.6 - 2.06E+06 - - - -0.2969 - 3.282 0.666 - 774.6 1 1 0 -0.0006 17 0 0 0 0.00E+00 2.79E+07 - - - 6.8817 0.9998 221125_WJC_METTL3_EV_vs_WT_F03.19912.19912.2 4.94E-07 15/22 K.TISAEIQDELSR.T "sp|Q9BVV6|TALD3_HUMAN,tr|A0A087WYM5|A0A087WYM5_HUMAN,tr|A0A494C0M8|A0A494C0M8_HUMAN,tr|A0A494C075|A0A494C075_HUMAN,tr|A0A494C0Z1|A0A494C0Z1_HUMAN,tr|A0A494C171|A0A494C171_HUMAN" 6 1360.6834 0.07 34887 19912 2 1360.685379 681.349 Protein TALPID3 OS=Homo sapiens OX=9606 GN=KIAA0586 PE=1 SV=4 4.14 3294.8 - 1.29E+06 - - - 1.4368 - 2.749 0.498 - 609.6 1 2 0 0.002 12 0 0 0 1.49E+07 2.15E+08 - - - 5.3794 0.9996 221125_WJC_METTL3_EV_vs_WT_F03.19917.19917.3 5.83E-06 Nov-36 R.RAPFDLFENR.K sp|P07900|HS90A_HUMAN 1 1263.636 0.49 34892 19917 3 1263.635358 422.2193 Heat shock protein HSP 90-alpha OS=Homo sapiens OX=9606 GN=HSP90AA1 PE=1 SV=5 6.07 3295.4 - 595103 - - - -0.5239 - 1.988 0.307 - 221.2 1 2 0 -0.0007 10 0 0 0 1.49E+07 3.04E+07 - - - 3.9693 0.9958 221125_WJC_METTL3_EV_vs_WT_F03.19920.19920.2 0.21 28-Nov K.EDSLAQAGETINALK[136.11].G "sp|Q9Y6D9|MD1L1_HUMAN,tr|C9JIR0|C9JIR0_HUMAN" 2 1566.7981 3.12 34894 19920 2 1566.795078 784.4063 Mitotic spindle assembly checkpoint protein MAD1 OS=Homo sapiens OX=9606 GN=MAD1L1 PE=1 SV=2 4.14 3295.8 - 400576 - - - -1.9071 - 1.842 0.165 - 238.4 1 2 0 -0.003 15 0 0 0 1.07E+07 3.42E+06 - - - 1.7606 1 221125_WJC_METTL3_EV_vs_WT_F03.19923.19923.3 4.15E-09 16/64 R.SLGYAYVNFQQPADAER[166.11].A "sp|Q13310|PABP4_HUMAN,sp|P11940|PABP1_HUMAN,tr|A0A7I2V649|A0A7I2V649_HUMAN,tr|B1ANR0|B1ANR0_HUMAN,tr|A0A7I2V4L7|A0A7I2V4L7_HUMAN,tr|E5RHG7|E5RHG7_HUMAN,tr|B1ANR1|B1ANR1_HUMAN,tr|H0YAR2|H0YAR2_HUMAN,tr|E7ERJ7|E7ERJ7_HUMAN,tr|E5RJB9|E5RJB9_HUMAN,tr|A0A7I2YQ88|A0A7I2YQ88_HUMAN,tr|E5RH24|E5RH24_HUMAN,tr|H0YBN4|H0YBN4_HUMAN,tr|E5RGH3|E5RGH3_HUMAN,tr|A0A087WTT1|A0A087WTT1_HUMAN,tr|A0A7I2YQ90|A0A7I2YQ90_HUMAN,tr|E7EQV3|E7EQV3_HUMAN" 17 1937.9147 1.45 34895 19923 3 1937.912983 646.9788 Polyadenylate-binding protein 4 OS=Homo sapiens OX=9606 GN=PABPC4 PE=1 SV=1 4.37 3296.2 - 1.86E+07 - - - -0.8917 - 3.269 0.592 - 269 1 2 0 -0.0017 17 0 0 0 2.66E+08 1.84E+08 - - - 8.1321 1 221125_WJC_METTL3_EV_vs_WT_F03.19928.19928.2 6.27E-09 17/28 R.NGSFGVLVATNVAAR[166.11].G sp|Q9NR30|DDX21_HUMAN 1 1484.7975 0.33 34900 19928 2 1484.797057 743.406 Nucleolar RNA helicase 2 OS=Homo sapiens OX=9606 GN=DDX21 PE=1 SV=5 9.75 3296.6 - 1.29E+06 - - - -0.2957 - 3.142 0.619 - 991.4 1 2 0 -0.0004 15 0 0 0 6.30E+06 1.91E+07 - - - 6.4275 0.9987 221125_WJC_METTL3_EV_vs_WT_F03.19930.19930.2 0.0117 20-Oct K.GDLDISYITSR[166.11].L sp|O14976|GAK_HUMAN 1 1248.6226 0.44 34902 19930 2 1248.620604 625.3186 Cyclin-G-associated kinase OS=Homo sapiens OX=9606 GN=GAK PE=1 SV=2 4.21 3296.9 - 765382 - - - -1.5601 - 1.678 0.285 - 270 1 2 0 -0.0019 11 0 0 0 4.00E+06 9.07E+06 - - - 2.5456 1 221125_WJC_METTL3_EV_vs_WT_F03.19931.19931.2 1.04E-07 15/32 R.TENPVIMGLSSQNGQLR.G "sp|P26196|DDX6_HUMAN,tr|Q8IV96|Q8IV96_HUMAN" 2 1842.9258 0.7 34903 19931 2 1842.923618 922.4702 Probable ATP-dependent RNA helicase DDX6 OS=Homo sapiens OX=9606 GN=DDX6 PE=1 SV=2 5.66 3297 - 724997 - - - -1.1818 - 2.99 0.564 - 586.4 1 2 0 -0.0022 17 0 0 0 6.79E+06 9.68E+06 - - - 5.8988 1 221125_WJC_METTL3_EV_vs_WT_F03.19936.19936.2 3.33E-08 18/28 K.APGMNTIDQGMAALK.L "sp|Q9Y5A9|YTHD2_HUMAN,tr|S4R3J8|S4R3J8_HUMAN,tr|S4R3V3|S4R3V3_HUMAN" 3 1516.7378 1.39 34907 19936 2 1516.737417 759.3762 YTH domain-containing family protein 2 OS=Homo sapiens OX=9606 GN=YTHDF2 PE=1 SV=2 5.88 3297.6 - 2.36E+07 - - - -0.242 - 3.841 0.694 - 1526 1 2 0 -0.0004 15 0 0 0 3.91E+08 2.81E+08 - - - 7.4753 0.9983 221125_WJC_METTL3_EV_vs_WT_F03.19937.19937.2 0.00738 13/24 R.AGSSESIAAFIQR[166.11].L "sp|P46379|BAG6_HUMAN,tr|A0A7I2V508|A0A7I2V508_HUMAN,tr|A0A7P0MQS5|A0A7P0MQS5_HUMAN,tr|A0A0G2JL47|A0A0G2JL47_HUMAN,tr|A0A024RCR6|A0A024RCR6_HUMAN,tr|A0A0G2JK23|A0A0G2JK23_HUMAN" 6 1345.6865 1.37 34908 19937 2 1345.688341 673.8506 Large proline-rich protein BAG6 OS=Homo sapiens OX=9606 GN=BAG6 PE=1 SV=2 6.05 3297.8 - 1.08E+06 - - - 1.3317 - 2.154 0.171 - 540.5 1 2 0 0.0018 13 0 0 0 5.78E+07 4.20E+07 - - - 2.2728 0.9987 221125_WJC_METTL3_EV_vs_WT_F03.19938.19938.2 0.000159 13/26 K.AVANESGLNFISVK[136.11].G sp|O15381|NVL_HUMAN 1 1455.7813 1.4 34909 19938 2 1455.774692 728.8979 Nuclear valosin-containing protein-like OS=Homo sapiens OX=9606 GN=NVL PE=1 SV=1 6.05 3297.9 - 1.10E+06 - - - -4.535 - 2.79 0.507 - 434.3 1 2 0 -0.0066 14 0 0 0 1.66E+07 1.19E+07 - - - 5.3584 0.9998 221125_WJC_METTL3_EV_vs_WT_F03.19939.19939.2 8.73E-05 22-Nov K.ADLINNLGTIAK[136.11].F "sp|Q58FF8|H90B2_HUMAN,sp|P08238|HS90B_HUMAN,sp|P07900|HS90A_HUMAN,sp|Q14568|HS902_HUMAN" 4 1249.7122 0.82 34910 19939 2 1249.71106 625.8634 Putative heat shock protein HSP 90-beta 2 OS=Homo sapiens OX=9606 GN=HSP90AB2P PE=1 SV=2 5.88 3298 - 811280 - - - -0.8738 - 2.265 0.442 - 543.7 1 2 0 -0.0011 12 0 0 0 9.96E+07 1.21E+08 - - - 4.4564 0.9999 221125_WJC_METTL3_EV_vs_WT_F03.19940.19940.3 0.000455 13/44 K.VSEQGLIEILKK.V "sp|O14737|PDCD5_HUMAN,tr|K7EQA1|K7EQA1_HUMAN" 2 1355.8024 1.51 34911 19940 3 1355.801748 452.9414 Programmed cell death protein 5 OS=Homo sapiens OX=9606 GN=PDCD5 PE=1 SV=3 6.11 3298.1 - 779126 - - - -0.4934 - 2.188 0.369 - 275.2 1 2 0 -0.0007 12 0 0 0 1.08E+07 7.17E+06 - - - 4.8241 0.9988 221125_WJC_METTL3_EV_vs_WT_F03.19943.19943.3 0.00268 Oct-48 R.YSVFR[166.11]PGVLLC[160.03]DR[166.11].Q "sp|Q9BUP3|HTAI2_HUMAN,tr|E9PI87|E9PI87_HUMAN" 2 1600.8299 0.36 34914 19943 3 1600.826074 534.6172 Oxidoreductase HTATIP2 OS=Homo sapiens OX=9606 GN=HTATIP2 PE=1 SV=2 8.22 3298.5 - 401179 - - - -2.3731 - 1.757 0.335 - 79.4 1 2 0 -0.0038 13 0 0 0 1.61E+06 4.54E+06 - - - 3.802 0.994 221125_WJC_METTL3_EV_vs_WT_F03.19946.19946.2 4.24E-05 13/22 R.SPSELFAQHIVT.L "sp|Q9Y2W1|TR150_HUMAN,tr|A0A3B3ITZ9|A0A3B3ITZ9_HUMAN" 2 1327.6772 - 34915 19946 2 1327.677645 664.8459 Thyroid hormone receptor-associated protein 3 OS=Homo sapiens OX=9606 GN=THRAP3 PE=1 SV=2 5.22 3298.9 - 3.36E+06 - - - 0.3231 - 2.651 0.501 - 465.3 1 1 0 0.0004 12 0 0 0 - - - - - 5.3065 1 221125_WJC_METTL3_EV_vs_WT_F03.19947.19947.3 0.000846 15/52 K.R[166.11]VESPVLPPVLVPR[166.11].H "sp|Q99717|SMAD5_HUMAN,sp|Q15797|SMAD1_HUMAN" 2 1576.9568 5.14 34916 19947 3 1576.956933 526.6595 Mothers against decapentaplegic homolog 5 OS=Homo sapiens OX=9606 GN=SMAD5 PE=1 SV=1 9.6 3299 - 3.65E+06 - - - 0.0919 - 2.656 0.519 - 409.2 1 2 0 0.0001 14 0 0 0 2.92E+08 5.69E+07 - - - 6.9222 0.9999 221125_WJC_METTL3_EV_vs_WT_F03.19948.19948.2 0.000469 15/22 K.ADLINNLGTIAK.F "sp|Q58FF8|H90B2_HUMAN,sp|P08238|HS90B_HUMAN,sp|P07900|HS90A_HUMAN,sp|Q14568|HS902_HUMAN" 4 1241.698 0.82 34917 19948 2 1241.698397 621.8563 Putative heat shock protein HSP 90-beta 2 OS=Homo sapiens OX=9606 GN=HSP90AB2P PE=1 SV=2 5.88 3299.1 - 1.57E+06 - - - 0.3584 - 2.949 0.504 - 482 1 2 0 0.0004 12 0 0 0 9.96E+07 1.21E+08 - - - 5.6089 1 221125_WJC_METTL3_EV_vs_WT_F03.19949.19949.3 4.15E-13 20/76 K.LIEAEDNMNC[160.03]QMSNITVTYR.D "sp|P62318|SMD3_HUMAN,tr|H3BT13|H3BT13_HUMAN" 2 2401.0712 1.45 34918 19949 3 2401.069191 801.3643 Small nuclear ribonucleoprotein Sm D3 OS=Homo sapiens OX=9606 GN=SNRPD3 PE=1 SV=1 4.14 3299.2 - 1.44E+06 - - - -0.8438 - 3.188 0.762 - 532 1 2 0 -0.002 20 0 0 0 3.54E+07 2.45E+07 - - - 9.8477 1 221125_WJC_METTL3_EV_vs_WT_F03.19950.19950.2 1.73E-07 17/30 R.AALEEVYPDLTPEETR.R sp|Q9H0D6|XRN2_HUMAN 1 1831.884 1.79 34919 19950 2 1831.88225 916.9493 5'-3' exoribonuclease 2 OS=Homo sapiens OX=9606 GN=XRN2 PE=1 SV=1 3.91 3299.4 - 694398 - - - -0.9411 - 3.535 0.556 - 751.7 1 2 0 -0.0017 16 0 0 0 7.31E+06 4.08E+06 - - - 6.2515 0.9913 221125_WJC_METTL3_EV_vs_WT_F03.19951.19951.2 8.29E-05 24-Nov S.SFQSMGSYGPFGR.M "sp|Q8ND56|LS14A_HUMAN,tr|A0A140TA76|A0A140TA76_HUMAN,tr|K7EMZ9|K7EMZ9_HUMAN" 3 1419.6241 0.69 34920 19951 2 1419.625241 710.8193 Protein LSM14 homolog A OS=Homo sapiens OX=9606 GN=LSM14A PE=1 SV=3 8.46 3299.5 - 329513 - - - 0.7791 - 2.074 0.533 - 305.5 1 1 0 0.0011 13 0 0 0 6.14E+06 8.88E+06 - - - 4.8496 0.9996 221125_WJC_METTL3_EV_vs_WT_F03.19953.19953.2 0.000126 28-Oct R.KFGYVDFESAEDLEK.A "sp|P19338|NUCL_HUMAN,tr|A0A7I2V506|A0A7I2V506_HUMAN,tr|A0A7I2V699|A0A7I2V699_HUMAN,tr|A0A7I2V2U7|A0A7I2V2U7_HUMAN,tr|A0A7I2V3F3|A0A7I2V3F3_HUMAN,tr|A0A7I2V428|A0A7I2V428_HUMAN,tr|A0A7I2V349|A0A7I2V349_HUMAN,tr|H7BY16|H7BY16_HUMAN,tr|A0A7I2V5M5|A0A7I2V5M5_HUMAN,tr|A0A7I2V2S8|A0A7I2V2S8_HUMAN,tr|C9JLB1|C9JLB1_HUMAN" 11 1775.8254 1.82 34922 19953 2 1775.830169 888.92 Nucleolin OS=Homo sapiens OX=9606 GN=NCL PE=1 SV=3 4.18 3299.8 - 218925 - - - 2.6872 - 2.453 0.503 - 198.3 1 2 0 0.0048 15 0 0 0 1.85E+06 1.02E+06 - - - 4.9607 1 221125_WJC_METTL3_EV_vs_WT_F03.19956.19956.3 1.84E-05 14/52 K.AC[160.03]QSIYPLHDVFVR.K "sp|P61247|RS3A_HUMAN,tr|D6R9B6|D6R9B6_HUMAN,tr|H0Y9Y4|H0Y9Y4_HUMAN,tr|D6RB09|D6RB09_HUMAN,tr|D6RAT0|D6RAT0_HUMAN,tr|D6RG13|D6RG13_HUMAN" 6 1703.8454 0.67 34923 19956 3 1703.846188 568.9557 40S ribosomal protein S3a OS=Homo sapiens OX=9606 GN=RPS3A PE=1 SV=2 6.78 3300.1 - 2.51E+06 - - - 0.4854 - 2.604 0.507 - 352.4 1 2 0 0.0008 14 0 0 0 3.89E+07 5.77E+07 - - - 6.7357 1 221125_WJC_METTL3_EV_vs_WT_F03.19959.19959.3 1.09E-10 21/80 A.TATAATAAAAAAAAYSDGYGR.V "sp|O43251|RFOX2_HUMAN,tr|B0QYV1|B0QYV1_HUMAN,tr|A0A0G2JRD1|A0A0G2JRD1_HUMAN,tr|A0A0G2JRA5|A0A0G2JRA5_HUMAN,tr|S4R3K7|S4R3K7_HUMAN" 5 1900.8915 1.24 34926 19959 3 1900.893568 634.6378 RNA binding protein fox-1 homolog 2 OS=Homo sapiens OX=9606 GN=RBFOX2 PE=1 SV=3 5.5 3300.3 - 2.29E+06 - - - 1.0779 - 3.995 0.613 - 631.6 1 1 0 0.002 21 0 0 0 3.18E+07 2.57E+07 - - - 8.6944 1 221125_WJC_METTL3_EV_vs_WT_F03.19960.19960.3 8.73E-06 Dec-64 R.TENPVIMGLSSQNGQLR[166.11].G "sp|P26196|DDX6_HUMAN,tr|Q8IV96|Q8IV96_HUMAN" 2 1852.9341 1.19 34927 19960 3 1852.93298 618.652 Probable ATP-dependent RNA helicase DDX6 OS=Homo sapiens OX=9606 GN=DDX6 PE=1 SV=2 5.66 3300.4 - 2.14E+06 - - - -0.5861 - 2.571 0.477 - 158.4 1 2 0 -0.0011 17 0 0 0 4.32E+07 3.64E+07 - - - 6.2434 0.9974 221125_WJC_METTL3_EV_vs_WT_F03.19961.19961.3 2.97E-07 22/80 A.TATAATAAAAAAAAYSDGYGR[166.11].V "sp|O43251|RFOX2_HUMAN,tr|B0QYV1|B0QYV1_HUMAN,tr|A0A0G2JRD1|A0A0G2JRD1_HUMAN,tr|A0A0G2JRA5|A0A0G2JRA5_HUMAN,tr|S4R3K7|S4R3K7_HUMAN" 5 1910.8998 1.25 34928 19961 3 1910.903246 637.9739 RNA binding protein fox-1 homolog 2 OS=Homo sapiens OX=9606 GN=RBFOX2 PE=1 SV=3 5.5 3300.4 - 1.85E+06 - - - 1.8091 - 3.433 0.548 - 582.5 1 1 0 0.0035 21 0 0 0 3.22E+07 2.57E+07 - - - 7.6058 1 221125_WJC_METTL3_EV_vs_WT_F03.19962.19962.3 1.05E-06 22/68 R.IGYQVTAMIGHTNVVVPR.S "sp|Q9H2P0|ADNP_HUMAN,tr|A0A2R8Y6X0|A0A2R8Y6X0_HUMAN,tr|A0A669KBJ7|A0A669KBJ7_HUMAN" 3 1954.0459 1.18 34929 19962 3 1954.046571 652.3559 Activity-dependent neuroprotector homeobox protein OS=Homo sapiens OX=9606 GN=ADNP PE=1 SV=1 8.75 3300.6 - 1.51E+06 - - - 0.368 - 3.973 0.522 - 458.1 1 2 0 0.0007 18 0 0 0 1.26E+07 1.07E+07 - - - 7.7947 1 221125_WJC_METTL3_EV_vs_WT_F03.19963.19963.3 6.10E-13 20/68 R.IGYQVTAMIGHTNVVVPR[166.11].S "sp|Q9H2P0|ADNP_HUMAN,tr|A0A2R8Y6X0|A0A2R8Y6X0_HUMAN,tr|A0A669KBJ7|A0A669KBJ7_HUMAN" 3 1964.0541 1.2 34930 19963 3 1964.058334 655.692 Activity-dependent neuroprotector homeobox protein OS=Homo sapiens OX=9606 GN=ADNP PE=1 SV=1 8.75 3300.7 - 1.49E+06 - - - 2.1445 - 4.379 0.527 - 326.6 1 2 0 0.0042 18 0 0 0 1.29E+07 1.07E+07 - - - 8.0918 0.9999 221125_WJC_METTL3_EV_vs_WT_F03.19964.19964.2 7.11E-06 13/22 R.GYISPYFINTSK.G "sp|P10809|CH60_HUMAN,tr|A0A7I2V2X6|A0A7I2V2X6_HUMAN,tr|A0A7I2V599|A0A7I2V599_HUMAN,tr|A0A7I2YQ71|A0A7I2YQ71_HUMAN,tr|E7ESH4|E7ESH4_HUMAN,tr|A0A7I2V5M1|A0A7I2V5M1_HUMAN,tr|A0A7I2V5K3|A0A7I2V5K3_HUMAN,tr|A0A7I2V369|A0A7I2V369_HUMAN" 8 1388.6976 1.29 34931 19964 2 1388.69904 695.3561 "60 kDa heat shock protein, mitochondrial OS=Homo sapiens OX=9606 GN=HSPD1 PE=1 SV=2" 8.5 3300.8 - 1.28E+06 - - - 1.0247 - 2.484 0.508 - 686.2 1 2 0 0.0014 12 0 0 0 4.47E+08 3.47E+08 - - - 5.1867 1 221125_WJC_METTL3_EV_vs_WT_F03.19965.19965.3 1.28E-09 21/60 R.FFVADTANEALEAAKR.L "sp|Q96I99|SUCB2_HUMAN,tr|E9PDQ8|E9PDQ8_HUMAN" 2 1751.8842 1.14 34932 19965 3 1751.889699 584.9687 "Succinate--CoA ligase [GDP-forming] subunit beta, mitochondrial OS=Homo sapiens OX=9606 GN=SUCLG2 PE=1 SV=2" 4.68 3300.9 - 1.23E+06 - - - 3.1109 - 3.591 0.615 - 524.8 1 2 0 0.0054 16 0 0 0 7.11E+06 6.25E+06 - - - 8.6754 1 221125_WJC_METTL3_EV_vs_WT_F03.19966.19966.2 1.60E-05 14/22 R.GYISPYFINTSK[136.11].G "sp|P10809|CH60_HUMAN,tr|A0A7I2V2X6|A0A7I2V2X6_HUMAN,tr|A0A7I2V599|A0A7I2V599_HUMAN,tr|A0A7I2YQ71|A0A7I2YQ71_HUMAN,tr|E7ESH4|E7ESH4_HUMAN,tr|A0A7I2V5M1|A0A7I2V5M1_HUMAN,tr|A0A7I2V5K3|A0A7I2V5K3_HUMAN,tr|A0A7I2V369|A0A7I2V369_HUMAN" 8 1396.7118 1.54 34933 19966 2 1396.712564 699.3632 "60 kDa heat shock protein, mitochondrial OS=Homo sapiens OX=9606 GN=HSPD1 PE=1 SV=2" 8.5 3301 - 1.03E+06 - - - 0.5348 - 2.687 0.601 - 731.7 1 2 0 0.0007 12 0 0 0 5.40E+08 3.50E+08 - - - 6.0805 0.8568 221125_WJC_METTL3_EV_vs_WT_F03.19967.19967.3 2.24 Sep-56 R.VAADMFSDGNFNWGR[166.11].V "sp|Q07812|BAX_HUMAN,tr|I6LPK7|I6LPK7_HUMAN,tr|K4JQN1|K4JQN1_HUMAN,tr|H0YA56|H0YA56_HUMAN" 4 1695.7339 0.001 34934 19967 3 1695.734567 566.2519 Apoptosis regulator BAX OS=Homo sapiens OX=9606 GN=BAX PE=1 SV=1 4.21 3301.1 - 990524 - - - 0.3874 - 1.229 0.103 - 62.2 1 2 0 0.0007 15 0 0 0 0.00E+00 8.77E+06 - - - 0.2262 1 221125_WJC_METTL3_EV_vs_WT_F03.19969.19969.2 1.01E-10 17/32 R.TENPVIMGLSSQNGQLR[166.11].G "sp|P26196|DDX6_HUMAN,tr|Q8IV96|Q8IV96_HUMAN" 2 1852.9341 0.8 34936 19969 2 1852.938522 927.4743 Probable ATP-dependent RNA helicase DDX6 OS=Homo sapiens OX=9606 GN=DDX6 PE=1 SV=2 5.66 3301.4 - 728007 - - - 2.4048 - 3.522 0.684 - 776.6 1 2 0 0.0045 17 0 0 0 6.79E+06 8.45E+06 - - - 7.187 0.9943 221125_WJC_METTL3_EV_vs_WT_F03.19970.19970.2 1.99E-06 24-Dec S.SFQSMGSYGPFGR[166.11].M "sp|Q8ND56|LS14A_HUMAN,tr|A0A140TA76|A0A140TA76_HUMAN,tr|K7EMZ9|K7EMZ9_HUMAN" 3 1429.6324 0.65 34937 19970 2 1429.6328 715.8235 Protein LSM14 homolog A OS=Homo sapiens OX=9606 GN=LSM14A PE=1 SV=3 8.46 3301.5 - 554284 - - - 0.2763 - 2.256 0.579 - 366.7 1 1 0 0.0004 13 0 0 0 6.14E+06 9.44E+06 - - - 5.4055 0.9821 221125_WJC_METTL3_EV_vs_WT_F03.19973.19973.2 0.000227 Oct-32 K.IDSIPHLNNSTPLVDPS.V sp|Q96I24|FUBP3_HUMAN 1 1817.9159 - 34940 19973 2 1817.917903 909.9652 Far upstream element-binding protein 3 OS=Homo sapiens OX=9606 GN=FUBP3 PE=1 SV=2 4.2 3301.9 - 351783 - - - 1.0782 - 2.053 0.425 - 155.6 1 1 0 0.002 17 0 0 0 - - - - - 3.9479 1 221125_WJC_METTL3_EV_vs_WT_F03.19974.19974.3 2.47E-05 Dec-44 K.DSLTLVFVETKK.G "sp|O00571|DDX3X_HUMAN,sp|O15523|DDX3Y_HUMAN,tr|A0A2R8YFR4|A0A2R8YFR4_HUMAN,tr|A0A2R8YCW1|A0A2R8YCW1_HUMAN,tr|A0A2R8YDH3|A0A2R8YDH3_HUMAN,tr|A0A2R8YDT5|A0A2R8YDT5_HUMAN,tr|A0A2R8Y645|A0A2R8Y645_HUMAN,tr|A0A2R8YF78|A0A2R8YF78_HUMAN,tr|A0A0D9SFB3|A0A0D9SFB3_HUMAN,tr|A0A2R8YFS5|A0A2R8YFS5_HUMAN,tr|A0A0D9SF53|A0A0D9SF53_HUMAN,tr|A0A0J9YVQ7|A0A0J9YVQ7_HUMAN,tr|A0A2R8Y5G6|A0A2R8Y5G6_HUMAN,tr|A0A2R8Y7T2|A0A2R8Y7T2_HUMAN,tr|A0A0D9SG12|A0A0D9SG12_HUMAN,tr|F6S8Q4|F6S8Q4_HUMAN,tr|A0A2U3TZJ9|A0A2U3TZJ9_HUMAN,tr|A0A2R8Y4A4|A0A2R8Y4A4_HUMAN" 18 1378.7708 0.52 34941 19974 3 1378.771959 460.5975 ATP-dependent RNA helicase DDX3X OS=Homo sapiens OX=9606 GN=DDX3X PE=1 SV=3 6.07 3302 - 344126 - - - 0.8537 - 2.332 0.512 - 208.8 1 2 0 0.0012 12 0 0 0 5.46E+06 1.05E+07 - - - 6.595 0.9997 221125_WJC_METTL3_EV_vs_WT_F03.19977.19977.3 0.000537 Dec-56 R.KFGYVDFESAEDLEK.A "sp|P19338|NUCL_HUMAN,tr|A0A7I2V506|A0A7I2V506_HUMAN,tr|A0A7I2V699|A0A7I2V699_HUMAN,tr|A0A7I2V2U7|A0A7I2V2U7_HUMAN,tr|A0A7I2V3F3|A0A7I2V3F3_HUMAN,tr|A0A7I2V428|A0A7I2V428_HUMAN,tr|A0A7I2V349|A0A7I2V349_HUMAN,tr|H7BY16|H7BY16_HUMAN,tr|A0A7I2V5M5|A0A7I2V5M5_HUMAN,tr|A0A7I2V2S8|A0A7I2V2S8_HUMAN,tr|C9JLB1|C9JLB1_HUMAN" 11 1775.8254 1.07 34943 19977 3 1775.828212 592.9491 Nucleolin OS=Homo sapiens OX=9606 GN=NCL PE=1 SV=3 4.18 3302.4 - 964704 - - - 1.5852 - 2.097 0.365 - 219.9 1 2 0 0.0028 15 0 0 0 3.78E+07 3.53E+07 - - - 4.5409 0.9271 221125_WJC_METTL3_EV_vs_WT_F03.19978.19978.2 3.90E-05 13/30 R.QLLDEVEVATEPAGSR[166.11].L sp|P78318|IGBP1_HUMAN 1 1722.8664 0.23 34944 19978 2 1724.875056 862.4405 Immunoglobulin-binding protein 1 OS=Homo sapiens OX=9606 GN=IGBP1 PE=1 SV=1 4 3302.5 - 437145 - - - 1165.9012 - 2.779 0.491 - 340.9 1 2 0 2.0087 16 0 0 0 4.18E+05 1.82E+06 - - - 4.5497 1 221125_WJC_METTL3_EV_vs_WT_F03.19979.19979.3 0.000344 14/72 K.VAYIPDEMAAQQNPLQQPR.G sp|O00425|IF2B3_HUMAN 1 2168.0684 1.76 34945 19979 3 2168.07088 723.6968 Insulin-like growth factor 2 mRNA-binding protein 3 OS=Homo sapiens OX=9606 GN=IGF2BP3 PE=1 SV=2 4.37 3302.6 - 2.17E+06 - - - 1.1263 - 3.056 0.533 - 232.7 1 2 0 0.0024 19 0 0 0 3.01E+07 1.72E+07 - - - 7.2263 0.9999 221125_WJC_METTL3_EV_vs_WT_F03.19980.19980.3 0.0018 15/84 K.YTPSGQAGAAASESLFVSNHAY.- "sp|P04075|ALDOA_HUMAN,tr|H3BR68|H3BR68_HUMAN,tr|J3KPS3|J3KPS3_HUMAN" 3 2227.0182 - 34946 19980 3 2227.015217 743.3467 Fructose-bisphosphate aldolase A OS=Homo sapiens OX=9606 GN=ALDOA PE=1 SV=2 5.24 3302.7 - 1.63E+06 - - - -1.3287 - 2.401 0.421 - 164.5 1 2 0 -0.003 22 0 0 0 - - - - - 5.3095 0.9997 221125_WJC_METTL3_EV_vs_WT_F03.19981.19981.3 0.0343 Sep-44 K.VSEQGLIEILK[136.11]K[136.11].V "sp|O14737|PDCD5_HUMAN,tr|K7EQA1|K7EQA1_HUMAN" 2 1371.8308 1.68 34947 19981 3 1371.830985 458.2842 Programmed cell death protein 5 OS=Homo sapiens OX=9606 GN=PDCD5 PE=1 SV=3 6.11 3302.8 - 1.25E+06 - - - 0.1225 - 1.88 0.348 - 124 1 2 0 0.0002 12 0 0 0 1.03E+07 6.11E+06 - - - 4.1696 1 221125_WJC_METTL3_EV_vs_WT_F03.19984.19984.2 2.59E-12 26/40 A.TATAATAAAAAAAAYSDGYGR[166.11].V "sp|O43251|RFOX2_HUMAN,tr|B0QYV1|B0QYV1_HUMAN,tr|A0A0G2JRD1|A0A0G2JRD1_HUMAN,tr|A0A0G2JRA5|A0A0G2JRA5_HUMAN,tr|S4R3K7|S4R3K7_HUMAN" 5 1910.8998 1.23 34950 19984 2 1910.898042 956.4572 RNA binding protein fox-1 homolog 2 OS=Homo sapiens OX=9606 GN=RBFOX2 PE=1 SV=3 5.5 3303.1 - 1.07E+06 - - - -0.9142 - 4.595 0.7 - 2044.7 1 1 0 -0.0017 21 0 0 0 8.00E+06 6.52E+06 - - - 7.9599 1 221125_WJC_METTL3_EV_vs_WT_F03.19985.19985.2 9.88E-15 25/40 A.TATAATAAAAAAAAYSDGYGR.V "sp|O43251|RFOX2_HUMAN,tr|B0QYV1|B0QYV1_HUMAN,tr|A0A0G2JRD1|A0A0G2JRD1_HUMAN,tr|A0A0G2JRA5|A0A0G2JRA5_HUMAN,tr|S4R3K7|S4R3K7_HUMAN" 5 1900.8915 1.23 34951 19985 2 1900.890944 951.453 RNA binding protein fox-1 homolog 2 OS=Homo sapiens OX=9606 GN=RBFOX2 PE=1 SV=3 5.5 3303.2 - 1.01E+06 - - - -0.3025 - 4.613 0.723 - 1883.7 1 1 0 -0.0006 21 0 0 0 8.00E+06 6.52E+06 - - - 8.1397 0.9998 221125_WJC_METTL3_EV_vs_WT_F03.19986.19986.3 0.0108 Dec-60 R.AALEEVYPDLTPEETR.R sp|Q9H0D6|XRN2_HUMAN 1 1831.884 4.92 34952 19986 3 1831.885246 611.6353 5'-3' exoribonuclease 2 OS=Homo sapiens OX=9606 GN=XRN2 PE=1 SV=1 3.91 3303.3 - 926829 - - - 0.6944 - 2.438 0.353 - 128.7 1 2 0 0.0013 16 0 0 0 1.09E+07 2.22E+06 - - - 4.7619 0.9997 221125_WJC_METTL3_EV_vs_WT_F03.19988.19988.2 0.0035 22-Oct K.DLLLNTMSQEEK.A sp|P78527|PRKDC_HUMAN 1 1419.6915 1.26 34954 19988 2 1419.692741 710.853 DNA-dependent protein kinase catalytic subunit OS=Homo sapiens OX=9606 GN=PRKDC PE=1 SV=3 4.14 3303.5 - 725016 - - - 0.8417 - 1.967 0.416 - 330.6 1 2 0 0.0012 12 0 0 0 4.80E+06 3.81E+06 - - - 3.8932 0.9996 221125_WJC_METTL3_EV_vs_WT_F03.19990.19990.2 5.72E-06 14/28 M.APVEHVVADAGAFLR[166.11].H "sp|Q9ULX3|NOB1_HUMAN,tr|H3BUR4|H3BUR4_HUMAN" 2 1560.8288 1.95 34956 19990 2 1560.833131 781.4217 RNA-binding protein NOB1 OS=Homo sapiens OX=9606 GN=NOB1 PE=1 SV=1 5.32 3303.7 - 493531 - - - 2.7774 - 2.854 0.523 - 392.5 1 2 0 0.0043 15 0 0 0 1.02E+07 5.25E+06 - - - 5.4808 0.9996 221125_WJC_METTL3_EV_vs_WT_F03.19992.19992.3 0.00311 16/60 R.VAVFSTLAPGVLHGAR.L "sp|Q6P4I2|WDR73_HUMAN,tr|H0YMT3|H0YMT3_HUMAN" 2 1593.8991 0.91 34958 19992 3 1593.905763 532.307 WD repeat-containing protein 73 OS=Homo sapiens OX=9606 GN=WDR73 PE=1 SV=1 9.73 3304 - 328866 - - - 4.1734 - 2.743 0.452 - 268.5 1 2 0 0.0067 16 0 0 0 5.35E+06 5.88E+06 - - - 6.1666 0.9998 221125_WJC_METTL3_EV_vs_WT_F03.19993.19993.2 0.000707 28-Nov K.ALEFIPSDQQNEMVR[166.11].E "sp|Q14671|PUM1_HUMAN,tr|H0YEH2|H0YEH2_HUMAN,tr|E9PR38|E9PR38_HUMAN" 3 1785.8595 3.93 34959 19993 2 1785.860807 893.937 Pumilio homolog 1 OS=Homo sapiens OX=9606 GN=PUM1 PE=1 SV=3 4.14 3304.1 - 313138 - - - 0.7296 - 2.403 0.381 - 278.8 1 2 0 0.0013 15 0 0 0 4.73E+07 1.20E+07 - - - 4.0101 1 221125_WJC_METTL3_EV_vs_WT_F03.19995.19995.3 1.10E-06 13/40 K.RPLFLAPDFDR.W "sp|Q9P035|HACD3_HUMAN,tr|H3BPZ1|H3BPZ1_HUMAN,tr|H3BS72|H3BS72_HUMAN" 3 1345.7143 0.12 34961 19995 3 1345.716982 449.5787 Very-long-chain (3R)-3-hydroxyacyl-CoA dehydratase 3 OS=Homo sapiens OX=9606 GN=HACD3 PE=1 SV=2 5.96 3304.4 - 248731 - - - 2.0153 - 2.301 0.545 - 361.1 1 2 0 0.0027 11 0 0 0 6.81E+06 5.59E+07 - - - 6.9828 0.9997 221125_WJC_METTL3_EV_vs_WT_F03.19997.19997.3 0.00319 Dec-48 K.LGWVR[166.11]PDLGELSK[136.11].V sp|P51970|NDUA8_HUMAN 1 1486.8263 1.1 34962 19997 3 1486.82692 496.616 NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 8 OS=Homo sapiens OX=9606 GN=NDUFA8 PE=1 SV=3 6.07 3304.6 - 1.57E+06 - - - 0.4278 - 2.233 0.316 - 164 1 2 0 0.0006 13 0 0 0 2.05E+07 1.87E+07 - - - 4.241 0.9682 221125_WJC_METTL3_EV_vs_WT_F03.19998.19998.2 0.000982 20-Oct K.FEIWDTAGQER.Y "sp|P61020|RAB5B_HUMAN,sp|P20339|RAB5A_HUMAN,sp|P51148|RAB5C_HUMAN,tr|F8VVZ0|F8VVZ0_HUMAN,tr|K7ERI8|K7ERI8_HUMAN,tr|F8VUA5|F8VUA5_HUMAN,tr|K7ENY4|K7ENY4_HUMAN,tr|K7ERQ8|K7ERQ8_HUMAN,tr|F8VWU4|F8VWU4_HUMAN,tr|F8VVK3|F8VVK3_HUMAN" 10 1350.6204 1.06 34963 19998 2 1351.626114 676.3175 Ras-related protein Rab-5B OS=Homo sapiens OX=9606 GN=RAB5B PE=1 SV=1 4.14 3304.7 - 1.88E+06 - - - 744.6089 - 1.71 0.414 - 362.4 1 2 0 1.0057 11 0 0 0 2.54E+07 2.39E+07 - - - 3.2344 0.8775 221125_WJC_METTL3_EV_vs_WT_F03.19999.19999.2 0.0454 22-Jul A.SEIEAVSVAMEK.E "sp|P28715|ERCC5_HUMAN,tr|A0A090HNM7|A0A090HNM7_HUMAN,tr|R4GMW8|R4GMW8_HUMAN,tr|A0A1W2PS85|A0A1W2PS85_HUMAN" 4 1291.633 2.55 34964 19999 2 1291.633467 646.8238 DNA excision repair protein ERCC-5 OS=Homo sapiens OX=9606 GN=ERCC5 PE=1 SV=3 4.25 3304.7 - 6.27E+06 - - - 0.3863 - 1.544 0.208 - 165.5 1 1 0 0.0005 12 0 0 0 3.67E+07 1.44E+07 - - - 1.72 1 221125_WJC_METTL3_EV_vs_WT_F03.20000.20000.3 1.82E-06 15/52 R.LTADMISHPLGDFR.H "sp|Q00587|BORG5_HUMAN,tr|B0QYC6|B0QYC6_HUMAN,tr|B0QYC7|B0QYC7_HUMAN,tr|B0QYC8|B0QYC8_HUMAN" 4 1571.7766 1.33 34965 20000 3 1571.778339 524.9328 Cdc42 effector protein 1 OS=Homo sapiens OX=9606 GN=CDC42EP1 PE=1 SV=1 5.21 3304.8 - 3.69E+06 - - - 1.0981 - 3.561 0.577 - 287 1 2 0 0.0017 14 0 0 0 3.13E+07 2.35E+07 - - - 8.3477 1 221125_WJC_METTL3_EV_vs_WT_F03.20001.20001.3 0.000513 15/52 R.LTADMISHPLGDFR[166.11].H "sp|Q00587|BORG5_HUMAN,tr|B0QYC6|B0QYC6_HUMAN,tr|B0QYC7|B0QYC7_HUMAN,tr|B0QYC8|B0QYC8_HUMAN" 4 1581.7849 1.33 34966 20001 3 1581.784749 528.2689 Cdc42 effector protein 1 OS=Homo sapiens OX=9606 GN=CDC42EP1 PE=1 SV=1 5.21 3304.8 - 3.47E+06 - - - -0.0847 - 3.017 0.508 - 268.2 1 2 0 -0.0001 14 0 0 0 3.13E+07 2.35E+07 - - - 7.1383 1 221125_WJC_METTL3_EV_vs_WT_F03.20002.20002.3 6.94E-10 14/72 K.VAYIPDEMAAQQNPLQQPR[166.11].G sp|O00425|IF2B3_HUMAN 1 2178.0767 1.76 34967 20002 3 2178.072509 727.0328 Insulin-like growth factor 2 mRNA-binding protein 3 OS=Homo sapiens OX=9606 GN=IGF2BP3 PE=1 SV=2 4.37 3304.9 - 2.06E+06 - - - -1.9278 - 3.048 0.587 - 215.4 1 2 0 -0.0042 19 0 0 0 2.73E+07 1.56E+07 - - - 7.8214 0.9999 221125_WJC_METTL3_EV_vs_WT_F03.20003.20003.2 8.28E-05 15/26 K.ALLLTGDFSQAGNK.G sp|Q9H2W6|RM46_HUMAN 1 1433.7514 0.94 34968 20003 2 1433.751378 717.883 "39S ribosomal protein L46, mitochondrial OS=Homo sapiens OX=9606 GN=MRPL46 PE=1 SV=1" 5.88 3305 - 1.31E+06 - - - -0.046 - 2.774 0.516 - 675 1 2 0 -0.0001 14 0 0 0 1.42E+07 1.51E+07 - - - 5.4125 1 221125_WJC_METTL3_EV_vs_WT_F03.20005.20005.3 4.91E-06 13/40 R.NLNGTLHELLR[166.11].M sp|P54886|P5CS_HUMAN 1 1288.7127 0.85 34970 20005 3 1288.712333 430.5782 Delta-1-pyrroline-5-carboxylate synthase OS=Homo sapiens OX=9606 GN=ALDH18A1 PE=1 SV=2 6.75 3305.2 - 1.12E+06 - - - -0.2879 - 3.008 0.507 - 347.4 1 2 0 -0.0004 11 0 0 0 4.43E+06 5.19E+06 - - - 7.321 0.9999 221125_WJC_METTL3_EV_vs_WT_F03.20007.20007.3 0.000492 Nov-44 K.DSLTLVFVETK[136.11]K[136.11].G "sp|O00571|DDX3X_HUMAN,sp|O15523|DDX3Y_HUMAN,tr|A0A2R8YFR4|A0A2R8YFR4_HUMAN,tr|A0A2R8YCW1|A0A2R8YCW1_HUMAN,tr|A0A2R8YDH3|A0A2R8YDH3_HUMAN,tr|A0A2R8YDT5|A0A2R8YDT5_HUMAN,tr|A0A2R8Y645|A0A2R8Y645_HUMAN,tr|A0A2R8YF78|A0A2R8YF78_HUMAN,tr|A0A0D9SFB3|A0A0D9SFB3_HUMAN,tr|A0A2R8YFS5|A0A2R8YFS5_HUMAN,tr|A0A0D9SF53|A0A0D9SF53_HUMAN,tr|A0A0J9YVQ7|A0A0J9YVQ7_HUMAN,tr|A0A2R8Y5G6|A0A2R8Y5G6_HUMAN,tr|A0A2R8Y7T2|A0A2R8Y7T2_HUMAN,tr|A0A0D9SG12|A0A0D9SG12_HUMAN,tr|F6S8Q4|F6S8Q4_HUMAN,tr|A0A2U3TZJ9|A0A2U3TZJ9_HUMAN,tr|A0A2R8Y4A4|A0A2R8Y4A4_HUMAN" 18 1394.7992 1.02 34972 20007 3 1394.798977 465.9403 ATP-dependent RNA helicase DDX3X OS=Homo sapiens OX=9606 GN=DDX3X PE=1 SV=3 6.07 3305.4 - 870572 - - - -0.147 - 2.207 0.388 - 155.4 1 2 0 -0.0002 12 0 0 0 4.02E+06 3.94E+06 - - - 5.0601 1 221125_WJC_METTL3_EV_vs_WT_F03.20009.20009.2 4.93E-14 18/34 K.AESLIGVYPEQGDC[160.03]VISK.V "sp|Q14683|SMC1A_HUMAN,tr|G8JLG1|G8JLG1_HUMAN,tr|A0A6Q8PHC3|A0A6Q8PHC3_HUMAN" 3 1963.9561 1.58 34974 20009 2 1963.959711 982.9853 Structural maintenance of chromosomes protein 1A OS=Homo sapiens OX=9606 GN=SMC1A PE=1 SV=2 4.14 3305.6 - 717899 - - - 1.8417 - 3.321 0.694 - 852.9 1 2 0 0.0036 18 0 0 0 3.97E+06 2.52E+06 - - - 7.1167 0.9999 221125_WJC_METTL3_EV_vs_WT_F03.20010.20010.3 7.52E-05 14/44 R.QAFFLHTTYFTK.F "sp|Q9BTC8|MTA3_HUMAN,tr|E7EQY4|E7EQY4_HUMAN,tr|E7EV10|E7EV10_HUMAN,tr|F6RRE2|F6RRE2_HUMAN" 4 1502.7558 0.36 34975 20010 3 1502.755713 501.9259 Metastasis-associated protein MTA3 OS=Homo sapiens OX=9606 GN=MTA3 PE=1 SV=2 8.6 3305.7 - 665877 - - - -0.0586 - 2.483 0.369 - 161.3 1 2 0 -0.0001 12 0 0 0 4.97E+06 1.38E+07 - - - 5.1749 1 221125_WJC_METTL3_EV_vs_WT_F03.20011.20011.2 1.05E-08 13/24 R.TTFTAEQLEELER.A sp|P23760|PAX3_HUMAN 1 1565.7573 1.73 34976 20011 2 1565.756325 783.8859 Paired box protein Pax-3 OS=Homo sapiens OX=9606 GN=PAX3 PE=1 SV=2 4.09 3305.9 - 626854 - - - -0.6336 - 2.87 0.593 - 570.6 1 2 0 -0.001 13 0 0 0 3.82E+06 2.21E+06 - - - 6.1265 1 221125_WJC_METTL3_EV_vs_WT_F03.20012.20012.2 1.33E-09 17/34 K.AESLIGVYPEQGDC[160.03]VISK[136.11].V "sp|Q14683|SMC1A_HUMAN,tr|G8JLG1|G8JLG1_HUMAN,tr|A0A6Q8PHC3|A0A6Q8PHC3_HUMAN" 3 1971.9703 1.58 34977 20012 2 1971.971279 986.9924 Structural maintenance of chromosomes protein 1A OS=Homo sapiens OX=9606 GN=SMC1A PE=1 SV=2 4.14 3306 - 574181 - - - 0.4995 - 2.938 0.644 - 705.2 1 2 0 0.001 18 0 0 0 3.97E+06 2.52E+06 - - - 6.4469 1 221125_WJC_METTL3_EV_vs_WT_F03.20014.20014.2 1.63E-09 13/42 K.YTPSGQAGAAASESLFVSNHAY.- "sp|P04075|ALDOA_HUMAN,tr|H3BR68|H3BR68_HUMAN,tr|J3KPS3|J3KPS3_HUMAN" 3 2227.0182 - 34979 20014 2 2227.014535 1114.5164 Fructose-bisphosphate aldolase A OS=Homo sapiens OX=9606 GN=ALDOA PE=1 SV=2 5.24 3306.3 - 531440 - - - -1.6349 - 2.974 0.656 - 328.9 1 2 0 -0.0036 22 0 0 0 - - - - - 6.5647 0.998 221125_WJC_METTL3_EV_vs_WT_F03.20015.20015.2 5.16E-07 Dec-32 K.LSPPYSSPQEFAQDVGR[166.11].M "sp|Q13263|TIF1B_HUMAN,tr|M0R0K9|M0R0K9_HUMAN" 2 1886.9038 0.64 34980 20015 2 1886.913418 944.4592 Transcription intermediary factor 1-beta OS=Homo sapiens OX=9606 GN=TRIM28 PE=1 SV=5 4.37 3306.4 - 431018 - - - 5.0909 - 2.113 0.61 - 157.4 1 2 0 0.0096 17 0 0 0 3.46E+07 5.44E+07 - - - 5.3827 0.9932 221125_WJC_METTL3_EV_vs_WT_F03.20018.20018.3 0.0107 Aug-36 R.KLSFFFDGTK.L "sp|Q8NCF5|NF2IP_HUMAN,tr|H3BSZ7|H3BSZ7_HUMAN" 2 1188.6179 1.07 34982 20018 3 1188.616608 397.2132 NFATC2-interacting protein OS=Homo sapiens OX=9606 GN=NFATC2IP PE=1 SV=1 8.59 3306.9 - 162447 - - - -1.0954 - 1.456 0.218 - 67.7 1 2 0 -0.0013 10 0 0 0 1.87E+06 1.74E+06 - - - 2.0673 1 221125_WJC_METTL3_EV_vs_WT_F03.20020.20020.3 2.76E-07 15/52 K.AC[160.03]QSIYPLHDVFVR[166.11].K "sp|P61247|RS3A_HUMAN,tr|D6R9B6|D6R9B6_HUMAN,tr|H0Y9Y4|H0Y9Y4_HUMAN,tr|D6RB09|D6RB09_HUMAN,tr|D6RAT0|D6RAT0_HUMAN,tr|D6RG13|D6RG13_HUMAN" 6 1713.8536 0.67 34983 20020 3 1713.854369 572.2918 40S ribosomal protein S3a OS=Homo sapiens OX=9606 GN=RPS3A PE=1 SV=2 6.78 3307.1 - 5.92E+06 - - - 0.4306 - 2.77 0.563 - 288.6 1 2 0 0.0007 14 0 0 0 3.89E+07 5.77E+07 - - - 7.5243 0.9999 221125_WJC_METTL3_EV_vs_WT_F03.20022.20022.2 0.000105 28-Dec K.ALEFIPSDQQNEMVR.E "sp|Q14671|PUM1_HUMAN,tr|H0YEH2|H0YEH2_HUMAN,tr|E9PR38|E9PR38_HUMAN" 3 1775.8512 3.93 34985 20022 2 1775.8515 888.9329 Pumilio homolog 1 OS=Homo sapiens OX=9606 GN=PUM1 PE=1 SV=3 4.14 3307.2 - 6.68E+06 - - - 0.1498 - 2.318 0.521 - 298.6 1 2 0 0.0003 15 0 0 0 4.73E+07 1.20E+07 - - - 4.9559 1 221125_WJC_METTL3_EV_vs_WT_F03.20026.20026.2 2.10E-09 14/24 K.QFAYQNSWGLTTR[166.11].T sp|P07814|SYEP_HUMAN 1 1580.7611 0.66 34989 20026 2 1580.761594 791.3878 Bifunctional glutamate\proline--tRNA ligase OS=Homo sapiens OX=9606 GN=EPRS1 PE=1 SV=5 8.75 3307.4 - 1.88E+06 - - - 0.3055 - 2.791 0.639 - 633.5 1 2 0 0.0005 13 0 0 0 1.37E+07 2.08E+07 - - - 6.3948 0.9791 221125_WJC_METTL3_EV_vs_WT_F03.20028.20028.3 0.000761 14/44 Q.IEGLKEELAYLR.K "sp|P08779|K1C16_HUMAN,tr|K7ENW6|K7ENW6_HUMAN" 2 1432.7926 129.9 34991 20028 3 1432.79331 478.6048 "Keratin, type I cytoskeletal 16 OS=Homo sapiens OX=9606 GN=KRT16 PE=1 SV=4" 4.79 3307.6 - 1.64E+06 - - - 0.5095 - 2.682 0.428 - 284 1 1 1 0.0007 12 0 0 0 9.62E+06 7.40E+04 - - - 6.0462 0.9999 221125_WJC_METTL3_EV_vs_WT_F03.20031.20031.3 0.000158 13/56 K.FTISDHPQPIDPLLK[136.11].N "sp|Q86VP6|CAND1_HUMAN,tr|A0A0C4DGH5|A0A0C4DGH5_HUMAN" 2 1727.9338 1.63 34994 20031 3 1727.933737 576.9852 Cullin-associated NEDD8-dissociated protein 1 OS=Homo sapiens OX=9606 GN=CAND1 PE=1 SV=2 5.21 3307.9 - 1.32E+06 - - - -0.0203 - 2.19 0.44 - 96.1 1 2 0 0 15 0 0 0 1.97E+07 1.20E+07 - - - 5.491 0.9999 221125_WJC_METTL3_EV_vs_WT_F03.20032.20032.3 1.25E-05 14/44 R.GYISPYFINTSK.G "sp|P10809|CH60_HUMAN,tr|A0A7I2V2X6|A0A7I2V2X6_HUMAN,tr|A0A7I2V599|A0A7I2V599_HUMAN,tr|A0A7I2YQ71|A0A7I2YQ71_HUMAN,tr|E7ESH4|E7ESH4_HUMAN,tr|A0A7I2V5M1|A0A7I2V5M1_HUMAN,tr|A0A7I2V5K3|A0A7I2V5K3_HUMAN,tr|A0A7I2V369|A0A7I2V369_HUMAN" 8 1388.6976 1.15 34995 20032 3 1388.69997 463.9065 "60 kDa heat shock protein, mitochondrial OS=Homo sapiens OX=9606 GN=HSPD1 PE=1 SV=2" 8.5 3308 - 1.17E+06 - - - 1.6944 - 2.368 0.443 - 206.4 1 2 0 0.0024 12 0 0 0 8.07E+06 7.02E+06 - - - 5.8678 1 221125_WJC_METTL3_EV_vs_WT_F03.20035.20035.3 1.25E-06 13/40 K.R[166.11]PLFLAPDFDR[166.11].W "sp|Q9P035|HACD3_HUMAN,tr|H3BPZ1|H3BPZ1_HUMAN,tr|H3BS72|H3BS72_HUMAN" 3 1365.7308 0.93 34998 20035 3 1365.729803 456.2509 Very-long-chain (3R)-3-hydroxyacyl-CoA dehydratase 3 OS=Homo sapiens OX=9606 GN=HACD3 PE=1 SV=2 5.96 3308.4 - 971238 - - - -0.7373 - 2.479 0.525 - 423.4 1 2 0 -0.001 11 0 0 0 5.90E+06 6.34E+06 - - - 6.972 1 221125_WJC_METTL3_EV_vs_WT_F03.20036.20036.2 7.86E-07 13/36 K.LNINPEDGMADYSDPSYVK[136.11].Q sp|Q99459|CDC5L_HUMAN 1 2134.9609 2.86 34999 20036 2 2134.960353 1068.4877 Cell division cycle 5-like protein OS=Homo sapiens OX=9606 GN=CDC5L PE=1 SV=2 3.84 3308.5 - 645323 - - - -0.2333 - 2.63 0.649 - 271.5 1 2 0 -0.0005 19 0 0 0 1.16E+07 4.05E+06 - - - 6.2117 0.9999 221125_WJC_METTL3_EV_vs_WT_F03.20038.20038.2 5.47E-06 13/30 K.LGLPPLTPEQQEALQK[136.11].A "sp|Q9UHX1|PUF60_HUMAN,tr|A0A0J9YYL3|A0A0J9YYL3_HUMAN,tr|A0A0J9YWM1|A0A0J9YWM1_HUMAN,tr|H0YEM1|H0YEM1_HUMAN,tr|E9PMU7|E9PMU7_HUMAN,tr|E9PN18|E9PN18_HUMAN,tr|E9PL19|E9PL19_HUMAN,tr|A0A0J9YVR6|A0A0J9YVR6_HUMAN,tr|A0A0J9YXX5|A0A0J9YXX5_HUMAN,tr|A0A0J9YXJ8|A0A0J9YXJ8_HUMAN,tr|E9PQ56|E9PQ56_HUMAN,tr|A0A0J9YVP6|A0A0J9YVP6_HUMAN" 12 1768.9814 1.28 35001 20038 2 1768.981839 885.498 Poly(U)-binding-splicing factor PUF60 OS=Homo sapiens OX=9606 GN=PUF60 PE=1 SV=1 4.53 3308.8 - 564829 - - - 0.2199 - 2.442 0.507 - 239.9 1 2 0 0.0004 16 0 0 0 7.03E+06 5.48E+06 - - - 4.9806 0.9996 221125_WJC_METTL3_EV_vs_WT_F03.20039.20039.3 0.00148 Oct-40 R.ETWEEAALHLK[136.11].N sp|Q9NV35|NUD15_HUMAN 1 1333.6758 5.16 35002 20039 3 1333.675788 445.5659 Nucleotide triphosphate diphosphatase NUDT15 OS=Homo sapiens OX=9606 GN=NUDT15 PE=1 SV=1 4.75 3308.9 - 554211 - - - 0.0165 - 1.856 0.34 - 82 1 2 0 0 11 0 0 0 1.16E+07 2.25E+06 - - - 4.0875 0.9998 221125_WJC_METTL3_EV_vs_WT_F03.20041.20041.2 1.25E-06 15/30 K.LGLPPLTPEQQEALQK.A "sp|Q9UHX1|PUF60_HUMAN,tr|A0A0J9YYL3|A0A0J9YYL3_HUMAN,tr|A0A0J9YWM1|A0A0J9YWM1_HUMAN,tr|H0YEM1|H0YEM1_HUMAN,tr|E9PMU7|E9PMU7_HUMAN,tr|E9PN18|E9PN18_HUMAN,tr|E9PL19|E9PL19_HUMAN,tr|A0A0J9YVR6|A0A0J9YVR6_HUMAN,tr|A0A0J9YXX5|A0A0J9YXX5_HUMAN,tr|A0A0J9YXJ8|A0A0J9YXJ8_HUMAN,tr|E9PQ56|E9PQ56_HUMAN,tr|A0A0J9YVP6|A0A0J9YVP6_HUMAN" 12 1760.9672 1.28 35003 20041 2 1760.969613 881.4909 Poly(U)-binding-splicing factor PUF60 OS=Homo sapiens OX=9606 GN=PUF60 PE=1 SV=1 4.53 3309.1 - 939211 - - - 1.3419 - 2.59 0.497 - 376.6 1 2 0 0.0024 16 0 0 0 7.03E+06 5.48E+06 - - - 5.0508 0.9999 221125_WJC_METTL3_EV_vs_WT_F03.20044.20044.2 0.00165 20-Dec K.FEIWDTAGQER[166.11].Y "sp|P61020|RAB5B_HUMAN,sp|P20339|RAB5A_HUMAN,sp|P51148|RAB5C_HUMAN,tr|F8VVZ0|F8VVZ0_HUMAN,tr|K7ERI8|K7ERI8_HUMAN,tr|F8VUA5|F8VUA5_HUMAN,tr|K7ENY4|K7ENY4_HUMAN,tr|K7ERQ8|K7ERQ8_HUMAN,tr|F8VWU4|F8VWU4_HUMAN,tr|F8VVK3|F8VVK3_HUMAN" 10 1360.6287 1.1 35006 20044 2 1360.629045 681.3216 Ras-related protein Rab-5B OS=Homo sapiens OX=9606 GN=RAB5B PE=1 SV=1 4.14 3309.4 - 3.08E+06 - - - 0.2536 - 2.589 0.481 - 562 1 2 0 0.0003 11 0 0 0 2.65E+07 2.40E+07 - - - 5.167 1 221125_WJC_METTL3_EV_vs_WT_F03.20045.20045.2 2.34E-06 13/28 R.QVVQTPNTVLSTPFR.T sp|Q99459|CDC5L_HUMAN 1 1685.9101 1.22 35007 20045 2 1685.910245 843.9623 Cell division cycle 5-like protein OS=Homo sapiens OX=9606 GN=CDC5L PE=1 SV=2 9.75 3309.4 - 2.91E+06 - - - 0.1038 - 3.196 0.594 - 400.7 1 2 0 0.0002 15 0 0 0 2.91E+07 2.39E+07 - - - 6.2848 0.9999 221125_WJC_METTL3_EV_vs_WT_F03.20046.20046.3 0.00162 17/52 K.ILLAELEQLKGQGK.S "sp|P08670|VIME_HUMAN,tr|B0YJC4|B0YJC4_HUMAN,tr|A0A1B0GTT5|A0A1B0GTT5_HUMAN" 3 1538.9032 1.8 35008 20046 3 1538.904453 513.975 Vimentin OS=Homo sapiens OX=9606 GN=VIM PE=1 SV=4 6.14 3309.5 - 2.21E+06 - - - 0.8181 - 3.188 0.468 - 377.4 1 2 1 0.0013 14 0 0 0 9.45E+08 5.26E+08 - - - 6.8385 0.9999 221125_WJC_METTL3_EV_vs_WT_F03.20047.20047.2 1.06E-07 14/22 R.AESLQQEVEALK.E "sp|Q14203|DCTN1_HUMAN,tr|A0A804CDA6|A0A804CDA6_HUMAN,tr|E7EX90|E7EX90_HUMAN,tr|A0A7P0Z4C3|A0A7P0Z4C3_HUMAN,tr|Q6AWB1|Q6AWB1_HUMAN" 5 1343.6933 2.36 35009 20047 2 1343.693651 672.8539 Dynactin subunit 1 OS=Homo sapiens OX=9606 GN=DCTN1 PE=1 SV=3 4.25 3309.6 - 1.68E+06 - - - 0.291 - 2.755 0.537 - 814.3 1 2 0 0.0004 12 0 0 0 6.93E+07 2.94E+07 - - - 5.6736 0.9999 221125_WJC_METTL3_EV_vs_WT_F03.20048.20048.3 0.0037 13/44 R.EFSLAGGIWHGR.A "sp|Q8WWM7|ATX2L_HUMAN,tr|A0A0C4DGL7|A0A0C4DGL7_HUMAN,tr|H3BRB0|H3BRB0_HUMAN" 3 1328.6626 3.13 35010 20048 3 1328.663703 443.8948 Ataxin-2-like protein OS=Homo sapiens OX=9606 GN=ATXN2L PE=1 SV=2 6.85 3309.7 - 1.49E+06 - - - 0.8535 - 2.406 0.348 - 313.8 1 2 0 0.0011 12 0 0 0 1.08E+07 3.46E+06 - - - 4.8531 0.9983 221125_WJC_METTL3_EV_vs_WT_F03.20049.20049.2 7.35E-07 14/30 R.AALEEVYPDLTPEETR[166.11].R sp|Q9H0D6|XRN2_HUMAN 1 1841.8922 1.4 35011 20049 2 1841.883108 921.9534 5'-3' exoribonuclease 2 OS=Homo sapiens OX=9606 GN=XRN2 PE=1 SV=1 3.91 3309.8 - 1.13E+06 - - - -4.9601 - 2.562 0.55 - 447.1 1 2 0 -0.0091 16 0 0 0 1.83E+07 1.31E+07 - - - 5.4134 1 221125_WJC_METTL3_EV_vs_WT_F03.20054.20054.2 1.75E-12 15/30 R.EIDDTYIEDAADVDAR.K sp|Q99459|CDC5L_HUMAN 1 1809.7905 1.93 35016 20054 2 1809.791528 905.9025 Cell division cycle 5-like protein OS=Homo sapiens OX=9606 GN=CDC5L PE=1 SV=2 3.57 3310.4 - 862984 - - - 0.5857 - 3.126 0.722 - 649.6 1 2 0 0.0011 16 0 0 0 2.25E+07 1.17E+07 - - - 7.1755 0.9998 221125_WJC_METTL3_EV_vs_WT_F03.20055.20055.4 0.000196 Dec-72 R.IMYTVFEHTFHVR[166.11].E "sp|P41250|GARS_HUMAN,tr|A0A6Q8PGI6|A0A6Q8PGI6_HUMAN,tr|A0A6Q8PGA8|A0A6Q8PGA8_HUMAN,tr|A0A6Q8PGW4|A0A6Q8PGW4_HUMAN,tr|A0A6Q8PGZ8|A0A6Q8PGZ8_HUMAN,tr|A0A6Q8PHH9|A0A6Q8PHH9_HUMAN,tr|A0A6Q8PHI7|A0A6Q8PHI7_HUMAN" 7 1688.8373 1.03 35017 20055 4 1688.837603 423.2166 Glycine--tRNA ligase OS=Homo sapiens OX=9606 GN=GARS1 PE=1 SV=3 6.92 3310.5 - 672140 - - - 0.2072 - 2.415 0.373 - 114.3 1 2 0 0.0003 13 0 0 0 4.35E+06 4.22E+06 - - - 2.7994 1 221125_WJC_METTL3_EV_vs_WT_F03.20056.20056.3 5.79E-05 13/48 R.IMYTVFEHTFHVR.E "sp|P41250|GARS_HUMAN,tr|A0A6Q8PGI6|A0A6Q8PGI6_HUMAN,tr|A0A6Q8PGA8|A0A6Q8PGA8_HUMAN,tr|A0A6Q8PGW4|A0A6Q8PGW4_HUMAN,tr|A0A6Q8PGZ8|A0A6Q8PGZ8_HUMAN,tr|A0A6Q8PHH9|A0A6Q8PHH9_HUMAN,tr|A0A6Q8PHI7|A0A6Q8PHI7_HUMAN" 7 1678.829 1.63 35018 20056 3 1678.828366 560.6169 Glycine--tRNA ligase OS=Homo sapiens OX=9606 GN=GARS1 PE=1 SV=3 6.92 3310.7 - 631404 - - - -0.3675 - 2.699 0.441 - 221.1 1 2 0 -0.0006 13 0 0 0 2.90E+06 1.78E+06 - - - 6.1485 0.9887 221125_WJC_METTL3_EV_vs_WT_F03.20059.20059.3 1.70E-05 13/76 R.LFPDSLEDTPPHFEGPPPPK.A tr|A0A2R8Y8D9|A0A2R8Y8D9_HUMAN 1 2216.079 8.99 35021 20059 3 2217.082102 739.7003 Proline and serine-rich protein 3 (Fragment) OS=Homo sapiens OX=9606 GN=PROSER3 PE=1 SV=1 4.31 3311.1 - 413491 - - - 452.6535 - 2.335 0.318 - 150.6 1 2 0 1.0031 20 0 0 0 2.80E+06 3.11E+05 - - - 3.8648 0.9986 221125_WJC_METTL3_EV_vs_WT_F03.20062.20062.3 0.00531 Dec-60 R.VAVFSTLAPGVLHGAR[166.11].L "sp|Q6P4I2|WDR73_HUMAN,tr|H0YMT3|H0YMT3_HUMAN" 2 1603.9074 0.91 35023 20062 3 1603.907423 535.6431 WD repeat-containing protein 73 OS=Homo sapiens OX=9606 GN=WDR73 PE=1 SV=1 9.73 3311.6 - 544191 - - - 0.0262 - 1.947 0.254 - 156.2 1 2 0 0 16 0 0 0 5.35E+06 5.88E+06 - - - 3.0814 0.9998 221125_WJC_METTL3_EV_vs_WT_F03.20064.20064.3 1.20E-05 18/52 K.ILLAELEQLK[136.11]GQGK[136.11].S "sp|P08670|VIME_HUMAN,tr|B0YJC4|B0YJC4_HUMAN,tr|A0A1B0GTT5|A0A1B0GTT5_HUMAN" 3 1554.9316 1.8 35024 20064 3 1554.931942 519.3178 Vimentin OS=Homo sapiens OX=9606 GN=VIM PE=1 SV=4 6.14 3311.8 - 1.66E+07 - - - 0.2244 - 3.342 0.39 - 429.4 1 2 1 0.0003 14 0 0 0 9.40E+08 5.22E+08 - - - 6.0945 0.995 221125_WJC_METTL3_EV_vs_WT_F03.20065.20065.2 0.00592 18-Nov K.GNSLQEILER.T "sp|Q00341|VIGLN_HUMAN,tr|A0A024R4E5|A0A024R4E5_HUMAN,tr|H7C0A4|H7C0A4_HUMAN" 3 1157.6041 1.72 35025 20065 2 1157.607439 579.8093 Vigilin OS=Homo sapiens OX=9606 GN=HDLBP PE=1 SV=2 4.53 3311.8 - 5.65E+06 - - - 2.9267 - 2.188 0.139 - 604.3 1 2 0 0.0034 10 0 0 0 4.77E+07 2.78E+07 - - - 2.2521 0.9999 221125_WJC_METTL3_EV_vs_WT_F03.20066.20066.3 0.000511 Nov-56 R.GFGFVYFQNHDAADK.A sp|Q13151|ROA0_HUMAN 1 1714.774 1.7 35026 20066 3 1714.77602 572.5986 Heterogeneous nuclear ribonucleoprotein A0 OS=Homo sapiens OX=9606 GN=HNRNPA0 PE=1 SV=1 5.21 3311.9 - 5.55E+06 - - - 1.1955 - 2.145 0.452 - 89.8 1 2 0 0.0021 15 0 0 0 5.69E+07 3.34E+07 - - - 5.5701 0.9997 221125_WJC_METTL3_EV_vs_WT_F03.20068.20068.2 0.104 18-Sep K.GNSLQEILER[166.11].T "sp|Q00341|VIGLN_HUMAN,tr|A0A024R4E5|A0A024R4E5_HUMAN,tr|H7C0A4|H7C0A4_HUMAN" 3 1167.6123 1.75 35028 20068 2 1167.613048 584.8134 Vigilin OS=Homo sapiens OX=9606 GN=HDLBP PE=1 SV=2 4.53 3312 - 3.18E+06 - - - 0.6226 - 2.223 0.344 - 338.2 1 2 0 0.0007 10 0 0 0 4.86E+07 2.78E+07 - - - 3.8114 1 221125_WJC_METTL3_EV_vs_WT_F03.20070.20070.2 3.18E-08 14/24 K.DFDFESANAQFNK[136.11].E "sp|Q8ND56|LS14A_HUMAN,tr|A0A140TA76|A0A140TA76_HUMAN,tr|K7EMZ9|K7EMZ9_HUMAN" 3 1539.6721 1.06 35030 20070 2 1539.670917 770.8433 Protein LSM14 homolog A OS=Homo sapiens OX=9606 GN=LSM14A PE=1 SV=3 4.03 3312.1 - 2.51E+06 - - - -0.7924 - 2.608 0.66 - 527.7 1 2 0 -0.0012 13 0 0 0 1.26E+08 1.19E+08 - - - 6.3756 1 221125_WJC_METTL3_EV_vs_WT_F03.20072.20072.3 3.05E-06 15/56 R.QVVQTPNTVLSTPFR.T sp|Q99459|CDC5L_HUMAN 1 1685.9101 1.08 35032 20072 3 1685.911179 562.9773 Cell division cycle 5-like protein OS=Homo sapiens OX=9606 GN=CDC5L PE=1 SV=2 9.75 3312.2 - 2.23E+06 - - - 0.6578 - 2.535 0.479 - 269.9 1 2 0 0.0011 15 0 0 0 1.42E+07 1.32E+07 - - - 6.3073 1 221125_WJC_METTL3_EV_vs_WT_F03.20073.20073.2 1.71E-12 18/30 R.EIDDTYIEDAADVDAR[166.11].K sp|Q99459|CDC5L_HUMAN 1 1819.7987 2 35033 20073 2 1819.796507 910.9066 Cell division cycle 5-like protein OS=Homo sapiens OX=9606 GN=CDC5L PE=1 SV=2 3.57 3312.4 - 1.89E+06 - - - -1.226 - 3.338 0.735 - 978 1 2 0 -0.0022 16 0 0 0 2.34E+07 1.17E+07 - - - 7.4325 1 221125_WJC_METTL3_EV_vs_WT_F03.20074.20074.3 1.50E-06 Dec-60 R.EIDDTYIEDAADVDAR.K sp|Q99459|CDC5L_HUMAN 1 1809.7905 1.64 35034 20074 3 1809.791633 604.2708 Cell division cycle 5-like protein OS=Homo sapiens OX=9606 GN=CDC5L PE=1 SV=2 3.57 3312.4 - 1.66E+06 - - - 0.6437 - 2.323 0.59 - 208.1 1 2 0 0.0012 16 0 0 0 9.64E+06 5.86E+06 - - - 7.2803 0.9989 221125_WJC_METTL3_EV_vs_WT_F03.20075.20075.2 0.00381 13/26 K.ILLAELEQLK[136.11]GQGK[136.11].S "sp|P08670|VIME_HUMAN,tr|B0YJC4|B0YJC4_HUMAN,tr|A0A1B0GTT5|A0A1B0GTT5_HUMAN" 3 1554.9316 1.77 35035 20075 2 1554.93127 778.4731 Vimentin OS=Homo sapiens OX=9606 GN=VIM PE=1 SV=4 6.14 3312.5 - 1.51E+06 - - - -0.2077 - 2.77 0.487 - 467.1 1 2 1 -0.0003 14 0 0 0 1.01E+08 5.70E+07 - - - 5.1946 0.9999 221125_WJC_METTL3_EV_vs_WT_F03.20077.20077.3 0.000389 Dec-48 K.VWILTDDSDIYKK.A sp|Q8IWA0|WDR75_HUMAN 1 1594.8243 1.02 35037 20077 3 1594.825632 532.6154 WD repeat-containing protein 75 OS=Homo sapiens OX=9606 GN=WDR75 PE=1 SV=1 4.43 3312.6 - 1.14E+06 - - - 0.8515 - 2.488 0.421 - 171.1 1 2 0 0.0014 13 0 0 0 6.56E+06 6.44E+06 - - - 5.7046 0.9999 221125_WJC_METTL3_EV_vs_WT_F03.20080.20080.3 0.00029 Nov-48 K.VWILTDDSDIYK[136.11]K[136.11].A sp|Q8IWA0|WDR75_HUMAN 1 1610.8527 1.08 35040 20080 3 1610.855449 537.9582 WD repeat-containing protein 75 OS=Homo sapiens OX=9606 GN=WDR75 PE=1 SV=1 4.43 3312.9 - 1.07E+06 - - - 1.7227 - 2.473 0.44 - 138.2 1 2 0 0.0028 13 0 0 0 6.96E+06 6.44E+06 - - - 5.8997 1 221125_WJC_METTL3_EV_vs_WT_F03.20081.20081.3 0.00127 13/40 K.IEDTVFHVFDK.V "sp|Q9Y2L1|RRP44_HUMAN,tr|G3V1J5|G3V1J5_HUMAN" 2 1348.6663 1.59 35041 20081 3 1348.667021 450.5627 Exosome complex exonuclease RRP44 OS=Homo sapiens OX=9606 GN=DIS3 PE=1 SV=2 4.54 3313 - 942368 - - - 0.522 - 2.324 0.468 - 334.3 1 2 0 0.0007 11 0 0 0 1.59E+08 1.00E+08 - - - 6.1532 0.9982 221125_WJC_METTL3_EV_vs_WT_F03.20082.20082.2 0.000988 22-Nov K.YNILGTNTIMDK.M "sp|Q00839|HNRPU_HUMAN,tr|A0A1W2PQL0|A0A1W2PQL0_HUMAN,tr|A0A1W2PPL4|A0A1W2PPL4_HUMAN,tr|A0A1W2PQ74|A0A1W2PQ74_HUMAN,tr|Q5RI18|Q5RI18_HUMAN,tr|A0A1W2PP35|A0A1W2PP35_HUMAN,tr|A0A1W2PPS1|A0A1W2PPS1_HUMAN,tr|A0A1W2PRZ7|A0A1W2PRZ7_HUMAN,tr|A0A1W2PPH7|A0A1W2PPH7_HUMAN,tr|A0A1W2PQD4|A0A1W2PQD4_HUMAN,tr|A0A1W2PP34|A0A1W2PP34_HUMAN,tr|A0A1X7SBS1|A0A1X7SBS1_HUMAN" 12 1381.6912 0.35 35042 20082 2 1381.696833 691.8529 Heterogeneous nuclear ribonucleoprotein U OS=Homo sapiens OX=9606 GN=HNRNPU PE=1 SV=6 5.83 3313.1 - 804826 - - - 4.1116 - 2.319 0.41 - 284.9 1 2 0 0.0057 12 0 0 0 1.59E+08 4.53E+08 - - - 4.2806 0.9999 221125_WJC_METTL3_EV_vs_WT_F03.20083.20083.2 5.91E-05 13/32 K.LSPPYSSPQEFAQDVGR.M "sp|Q13263|TIF1B_HUMAN,tr|M0R0K9|M0R0K9_HUMAN" 2 1876.8955 0.64 35043 20083 2 1876.896785 939.455 Transcription intermediary factor 1-beta OS=Homo sapiens OX=9606 GN=TRIM28 PE=1 SV=5 4.37 3313.2 - 745202 - - - 0.6623 - 2.482 0.513 - 208.7 1 2 0 0.0012 17 0 0 0 3.46E+07 5.44E+07 - - - 5.0646 0.9935 221125_WJC_METTL3_EV_vs_WT_F03.20086.20086.2 0.053 14-Jul R.ENFQNWLK.D "sp|P37802|TAGL2_HUMAN,tr|X6RJP6|X6RJP6_HUMAN" 2 1077.5243 1.89 35045 20086 2 1077.528268 539.7694 Transgelin-2 OS=Homo sapiens OX=9606 GN=TAGLN2 PE=1 SV=3 6.1 3313.6 - 1.31E+06 - - - 3.6417 - 1.624 0.266 - 161.9 1 2 0 0.0039 8 0 0 0 8.45E+06 4.48E+06 - - - 2.4669 1 221125_WJC_METTL3_EV_vs_WT_F03.20087.20087.2 4.08E-07 24-Nov K.DFDFESANAQFNK.E "sp|Q8ND56|LS14A_HUMAN,tr|A0A140TA76|A0A140TA76_HUMAN,tr|K7EMZ9|K7EMZ9_HUMAN" 3 1531.6579 1.05 35046 20087 2 1531.657593 766.8362 Protein LSM14 homolog A OS=Homo sapiens OX=9606 GN=LSM14A PE=1 SV=3 4.03 3313.6 - 5.83E+06 - - - -0.2246 - 2.618 0.662 - 279.9 1 2 0 -0.0003 13 0 0 0 1.26E+08 1.20E+08 - - - 6.4005 0.9998 221125_WJC_METTL3_EV_vs_WT_F03.20088.20088.2 0.000106 22-Sep R.AESLQQEVEALK[136.11].E "sp|Q14203|DCTN1_HUMAN,tr|A0A804CDA6|A0A804CDA6_HUMAN,tr|E7EX90|E7EX90_HUMAN,tr|A0A7P0Z4C3|A0A7P0Z4C3_HUMAN,tr|Q6AWB1|Q6AWB1_HUMAN" 5 1351.7075 2.36 35047 20088 2 1351.707254 676.861 Dynactin subunit 1 OS=Homo sapiens OX=9606 GN=DCTN1 PE=1 SV=3 4.25 3313.7 - 4.03E+06 - - - -0.1524 - 1.921 0.442 - 210.3 1 2 0 -0.0002 12 0 0 0 6.93E+07 2.94E+07 - - - 4.0233 1 221125_WJC_METTL3_EV_vs_WT_F03.20090.20090.3 0.00015 14/40 K.IEDTVFHVFDK[136.11].V "sp|Q9Y2L1|RRP44_HUMAN,tr|G3V1J5|G3V1J5_HUMAN" 2 1356.6805 1.59 35049 20090 3 1356.680618 453.2341 Exosome complex exonuclease RRP44 OS=Homo sapiens OX=9606 GN=DIS3 PE=1 SV=2 4.54 3313.8 - 1.75E+06 - - - 0.0744 - 2.582 0.517 - 502.7 1 2 0 0.0001 11 0 0 0 1.59E+08 1.00E+08 - - - 6.9987 1 221125_WJC_METTL3_EV_vs_WT_F03.20092.20092.2 6.75E-11 17/28 K.AFLDALQNQAEASSK.L sp|Q12931|TRAP1_HUMAN 1 1591.7842 2.1 35051 20092 2 1591.785657 796.8994 "Heat shock protein 75 kDa, mitochondrial OS=Homo sapiens OX=9606 GN=TRAP1 PE=1 SV=3" 4.37 3314 - 1.37E+06 - - - 0.9147 - 3.714 0.691 - 1059.7 1 2 0 0.0015 15 0 0 0 5.76E+07 2.75E+07 - - - 7.3702 0.9818 221125_WJC_METTL3_EV_vs_WT_F03.20094.20094.3 0.00012 13/44 S.ADIETIGEILKK.L "sp|P61978|HNRPK_HUMAN,tr|Q5T6W2|Q5T6W2_HUMAN" 2 1328.7551 1.04 35053 20094 3 1328.754114 443.9257 Heterogeneous nuclear ribonucleoprotein K OS=Homo sapiens OX=9606 GN=HNRNPK PE=1 SV=1 4.68 3314.1 - 1.31E+06 - - - -0.7661 - 2.349 0.338 - 313.3 1 1 0 -0.001 12 0 0 0 6.77E+06 6.52E+06 - - - 4.6752 0.9965 221125_WJC_METTL3_EV_vs_WT_F03.20095.20095.2 0.183 12-Jul K.DLQNFLK.K sp|P06702|S10A9_HUMAN 1 876.4705 21.11 35054 20095 2 876.470361 439.2425 Protein S100-A9 OS=Homo sapiens OX=9606 GN=S100A9 PE=1 SV=1 5.84 3314.2 - 1.06E+06 - - - -0.1791 - 1.329 0.191 - 142.1 1 2 0 -0.0002 7 0 0 0 1.68E+07 7.96E+05 - - - 1.3529 0.957 221125_WJC_METTL3_EV_vs_WT_F03.20096.20096.2 0.0127 22-Aug A.VDVDTGMNAELK.Y "sp|Q9HC56|PCDH9_HUMAN,tr|Q5VT82|Q5VT82_HUMAN,tr|B7ZM79|B7ZM79_HUMAN" 3 1290.6126 9.19 35055 20096 2 1290.612814 646.3136 Protocadherin-9 OS=Homo sapiens OX=9606 GN=PCDH9 PE=1 SV=2 4.03 3314.4 - 985361 - - - 0.1914 - 1.431 0.361 - 146.1 1 1 0 0.0002 12 0 0 0 1.70E+07 1.86E+06 - - - 2.6502 1 221125_WJC_METTL3_EV_vs_WT_F03.20097.20097.2 3.18E-09 17/28 K.AFLDALQNQAEASSK[136.11].L sp|Q12931|TRAP1_HUMAN 1 1599.7984 2.13 35056 20097 2 1599.800936 800.9065 "Heat shock protein 75 kDa, mitochondrial OS=Homo sapiens OX=9606 GN=TRAP1 PE=1 SV=3" 4.37 3314.5 - 802429 - - - 1.5846 - 3.499 0.627 - 1091.2 1 2 0 0.0025 15 0 0 0 5.78E+07 2.71E+07 - - - 6.7505 0.9989 221125_WJC_METTL3_EV_vs_WT_F03.20101.20101.2 9.65E-05 16/32 R.LGGAVLSFSEATSSVQK.G "sp|P27708|PYR1_HUMAN,tr|F8VPD4|F8VPD4_HUMAN,tr|H7C2E4|H7C2E4_HUMAN" 3 1679.873 0.52 35060 20101 2 1679.878281 840.9438 CAD protein OS=Homo sapiens OX=9606 GN=CAD PE=1 SV=3 6 3315 - 675561 - - - 3.1342 - 2.859 0.322 - 414.9 1 2 0 0.0053 17 0 0 0 6.20E+06 1.19E+07 - - - 4.0003 0.9999 221125_WJC_METTL3_EV_vs_WT_F03.20102.20102.3 9.01E-06 13/60 K.FHLQNTLYPQYDPVYR.L "sp|Q6KC79|NIPBL_HUMAN,tr|A0A590UJS4|A0A590UJS4_HUMAN" 2 2053.0058 1 35061 20102 3 2053.006408 685.3425 Nipped-B-like protein OS=Homo sapiens OX=9606 GN=NIPBL PE=1 SV=2 6.74 3315.2 - 621483 - - - 0.3151 - 2.531 0.394 - 153.3 1 2 0 0.0006 16 0 0 0 3.68E+06 3.67E+06 - - - 5.3152 0.9997 221125_WJC_METTL3_EV_vs_WT_F03.20103.20103.2 0.000785 24-Oct R.MVIITGPPEAQFK.A "sp|Q9NZI8|IF2B1_HUMAN,sp|O00425|IF2B3_HUMAN,sp|Q9Y6M1|IF2B2_HUMAN,tr|F8W930|F8W930_HUMAN" 4 1429.7639 -1 35062 20103 2 1429.763272 715.8892 Insulin-like growth factor 2 mRNA-binding protein 1 OS=Homo sapiens OX=9606 GN=IGF2BP1 PE=1 SV=2 5.75 3315.3 - 613130 - - - -0.4553 - 1.993 0.399 - 322.3 1 2 0 -0.0007 13 0 0 0 0.00E+00 0.00E+00 - - - 3.7578 0.9971 221125_WJC_METTL3_EV_vs_WT_F03.20106.20106.2 0.000394 26-Sep R.LEITPVVC[160.03]NVEQVR[166.11].L sp|Q9UI36|DACH1_HUMAN 1 1664.8795 1.97 35064 20106 2 1664.872434 833.447 Dachshund homolog 1 OS=Homo sapiens OX=9606 GN=DACH1 PE=1 SV=4 4.53 3315.8 - 244971 - - - -4.2514 - 1.914 0.418 - 207.9 1 2 0 -0.0071 14 0 0 0 4.29E+06 2.18E+06 - - - 3.7552 0.9966 221125_WJC_METTL3_EV_vs_WT_F03.20111.20111.3 0.000603 Dec-68 R.LINK[136.11]PGPDTFPDYGDVLR[166.11].A sp|Q9UER7|DAXX_HUMAN 1 2034.0541 1.2 35069 20111 3 2034.044776 679.0253 Death domain-associated protein 6 OS=Homo sapiens OX=9606 GN=DAXX PE=1 SV=2 4.43 3316.1 - 2.15E+06 - - - -4.5898 - 2.083 0.35 - 163.7 1 2 0 -0.0093 18 0 0 0 1.21E+07 1.01E+07 - - - 4.2668 0.9985 221125_WJC_METTL3_EV_vs_WT_F03.20112.20112.2 0.0239 18-Sep K.IAC[160.03]LDFSLQK[136.11].T "sp|P17987|TCPA_HUMAN,tr|F5GZ03|F5GZ03_HUMAN,tr|F5H282|F5H282_HUMAN,tr|E7EQR6|E7EQR6_HUMAN,tr|E7ERF2|E7ERF2_HUMAN" 5 1201.6256 0.33 35070 20112 2 1201.622666 601.8201 T-complex protein 1 subunit alpha OS=Homo sapiens OX=9606 GN=TCP1 PE=1 SV=1 5.83 3316.2 - 1.85E+06 - - - -2.4791 - 1.842 0.306 - 154.8 1 2 0 -0.003 10 0 0 0 4.14E+06 1.24E+07 - - - 3.0053 0.9248 221125_WJC_METTL3_EV_vs_WT_F03.20114.20114.2 0.00181 17/22 L.LAELEQLK[136.11]GQGK[136.11].S "sp|P08670|VIME_HUMAN,tr|B0YJC4|B0YJC4_HUMAN,tr|A0A1B0GTT5|A0A1B0GTT5_HUMAN" 3 1328.7635 2.1 35072 20114 2 1328.76251 665.389 Vimentin OS=Homo sapiens OX=9606 GN=VIM PE=1 SV=4 6.14 3316.4 - 1.62E+06 - - - -0.7187 - 3.041 0.411 - 1196.7 1 1 1 -0.001 12 0 0 0 2.56E+07 1.22E+07 - - - 5.0027 1 221125_WJC_METTL3_EV_vs_WT_F03.20115.20115.2 2.13E-12 20/34 K.IDLPAENSNSETIIITGK.R "sp|Q00341|VIGLN_HUMAN,tr|A0A024R4E5|A0A024R4E5_HUMAN,tr|H7BZC3|H7BZC3_HUMAN,tr|H7C2D1|H7C2D1_HUMAN,tr|H0Y394|H0Y394_HUMAN" 5 1913.9946 1.43 35073 20115 2 1913.99298 958.0046 Vigilin OS=Homo sapiens OX=9606 GN=HDLBP PE=1 SV=2 4.14 3316.5 - 1.49E+06 - - - -0.8396 - 3.693 0.735 - 1191.6 1 2 0 -0.0016 18 0 0 0 1.92E+07 1.34E+07 - - - 7.6811 0.9999 221125_WJC_METTL3_EV_vs_WT_F03.20116.20116.3 2.80E-05 Oct-48 K.DFDFESANAQFNK.E "sp|Q8ND56|LS14A_HUMAN,tr|A0A140TA76|A0A140TA76_HUMAN,tr|K7EMZ9|K7EMZ9_HUMAN" 3 1531.6579 1.99 35074 20116 3 1531.660213 511.5599 Protein LSM14 homolog A OS=Homo sapiens OX=9606 GN=LSM14A PE=1 SV=3 4.03 3316.6 - 1.27E+06 - - - 1.486 - 1.532 0.534 - 101.2 1 2 0 0.0023 13 0 0 0 8.62E+06 4.34E+06 - - - 5.6495 1 221125_WJC_METTL3_EV_vs_WT_F03.20117.20117.3 1.19E-07 14/60 K.IEVIKPGDLGVDLTSK.L "sp|P38117|ETFB_HUMAN,tr|M0QY67|M0QY67_HUMAN" 2 1682.9455 2.09 35075 20117 3 1682.942094 561.9891 Electron transfer flavoprotein subunit beta OS=Homo sapiens OX=9606 GN=ETFB PE=1 SV=3 4.56 3316.6 - 1.25E+06 - - - -1.9953 - 2.804 0.549 - 171.3 1 2 0 -0.0034 16 0 0 0 7.21E+07 3.45E+07 - - - 7.3054 1 221125_WJC_METTL3_EV_vs_WT_F03.20118.20118.2 2.76E-05 18/24 L.LLAELEQLKGQGK.S "sp|P08670|VIME_HUMAN,tr|B0YJC4|B0YJC4_HUMAN,tr|A0A1B0GTT5|A0A1B0GTT5_HUMAN" 3 1425.8191 2.98 35076 20118 2 1425.819104 713.9168 Vimentin OS=Homo sapiens OX=9606 GN=VIM PE=1 SV=4 6.14 3316.8 - 1.03E+06 - - - -0.0175 - 3.157 0.541 - 1092.5 1 1 1 0 13 0 0 0 9.12E+06 3.06E+06 - - - 5.9874 1 221125_WJC_METTL3_EV_vs_WT_F03.20120.20120.2 9.78E-09 14/28 Y.AGYPSQFVPGLDPSK.S sp|Q9H7S9|ZN703_HUMAN 1 1561.7777 1.65 35078 20120 2 1561.774227 781.8961 Zinc finger protein 703 OS=Homo sapiens OX=9606 GN=ZNF703 PE=1 SV=1 5.88 3317 - 962121 - - - -2.1975 - 2.456 0.626 - 439.5 1 1 0 -0.0034 15 0 0 0 3.53E+07 2.13E+07 - - - 5.8726 0.9999 221125_WJC_METTL3_EV_vs_WT_F03.20121.20121.3 5.78E-05 Nov-40 R.TVIDGLDLLKK.E sp|Q9UPR3|SMG5_HUMAN 1 1213.7282 0.93 35079 20121 3 1213.727347 405.5833 Protein SMG5 OS=Homo sapiens OX=9606 GN=SMG5 PE=1 SV=3 5.63 3317.1 - 696839 - - - -0.6937 - 1.907 0.427 - 100.4 1 2 0 -0.0008 11 0 0 0 2.44E+06 2.63E+06 - - - 5.1342 1 221125_WJC_METTL3_EV_vs_WT_F03.20125.20125.2 1.09E-07 13/26 K.EIFEQPESVVNTMR[166.11].G "sp|Q06210|GFPT1_HUMAN,tr|A0A6I8PRN4|A0A6I8PRN4_HUMAN,tr|A0A6I8PTT9|A0A6I8PTT9_HUMAN" 3 1687.8115 1.28 35081 20125 2 1687.808482 844.913 Glutamine--fructose-6-phosphate aminotransferase [isomerizing] 1 OS=Homo sapiens OX=9606 GN=GFPT1 PE=1 SV=3 4.25 3317.7 - 3.11E+06 - - - -1.7828 - 2.717 0.578 - 380.1 1 2 0 -0.003 14 0 0 0 4.60E+07 3.60E+07 - - - 5.8174 1 221125_WJC_METTL3_EV_vs_WT_F03.20126.20126.2 5.51E-08 15/26 K.EIFEQPESVVNTMR.G "sp|Q06210|GFPT1_HUMAN,tr|A0A6I8PRN4|A0A6I8PRN4_HUMAN,tr|A0A6I8PTT9|A0A6I8PTT9_HUMAN" 3 1677.8032 1.28 35082 20126 2 1677.800415 839.9089 Glutamine--fructose-6-phosphate aminotransferase [isomerizing] 1 OS=Homo sapiens OX=9606 GN=GFPT1 PE=1 SV=3 4.25 3317.7 - 4.66E+06 - - - -1.6724 - 3.035 0.595 - 511.3 1 2 0 -0.0028 14 0 0 0 4.60E+07 3.60E+07 - - - 6.2208 0.9999 221125_WJC_METTL3_EV_vs_WT_F03.20127.20127.3 2.26E-06 13/44 R.AR[166.11]FEELNADLFR[166.11].G "sp|P54652|HSP72_HUMAN,sp|P11142|HSP7C_HUMAN,tr|E9PNE6|E9PNE6_HUMAN,tr|A8K7Q2|A8K7Q2_HUMAN,tr|E9PKE3|E9PKE3_HUMAN,tr|E9PN89|E9PN89_HUMAN" 6 1499.7636 0.16 35083 20127 3 1499.762422 500.9285 Heat shock-related 70 kDa protein 2 OS=Homo sapiens OX=9606 GN=HSPA2 PE=1 SV=1 4.68 3317.8 - 2.97E+07 - - - -0.7635 - 2.609 0.537 - 385.7 1 2 1 -0.0011 12 0 0 0 9.63E+08 5.91E+09 - - - 7.1848 1 221125_WJC_METTL3_EV_vs_WT_F03.20128.20128.2 0.00123 19/22 R.AR[166.11]FEELNADLFR[166.11].G "sp|P54652|HSP72_HUMAN,sp|P11142|HSP7C_HUMAN,tr|E9PNE6|E9PNE6_HUMAN,tr|A8K7Q2|A8K7Q2_HUMAN,tr|E9PKE3|E9PKE3_HUMAN,tr|E9PN89|E9PN89_HUMAN" 6 1499.7636 0.15 35084 20128 2 1499.761801 750.8891 Heat shock-related 70 kDa protein 2 OS=Homo sapiens OX=9606 GN=HSPA2 PE=1 SV=1 4.68 3317.8 - 4.10E+06 - - - -1.1775 - 3.21 0.547 - 690.4 1 2 1 -0.0018 12 0 0 0 1.70E+08 1.10E+09 - - - 6.1492 0.9999 221125_WJC_METTL3_EV_vs_WT_F03.20129.20129.3 0.000183 Nov-48 K.AVLWQDSFSPHLK.H "sp|Q14671|PUM1_HUMAN,tr|Q5T1Z8|Q5T1Z8_HUMAN,tr|E9PM68|E9PM68_HUMAN,tr|E9PMX1|E9PMX1_HUMAN,tr|H0YEH2|H0YEH2_HUMAN,tr|Q5T1Z4|Q5T1Z4_HUMAN,tr|E9PL65|E9PL65_HUMAN,tr|E9PR38|E9PR38_HUMAN" 8 1526.7882 2.26 35085 20129 3 1526.789407 509.9367 Pumilio homolog 1 OS=Homo sapiens OX=9606 GN=PUM1 PE=1 SV=3 6.79 3317.9 - 3.13E+06 - - - 0.8141 - 1.908 0.408 - 117.6 1 2 0 0.0012 13 0 0 0 1.63E+08 7.18E+07 - - - 4.8401 0.9996 221125_WJC_METTL3_EV_vs_WT_F03.20130.20130.2 1.04E-05 26-Dec R.IWSVPNASC[160.03]VQVVR.A sp|Q9UMS4|PRP19_HUMAN 1 1613.8348 1.07 35086 20130 2 1613.830629 807.9247 Pre-mRNA-processing factor 19 OS=Homo sapiens OX=9606 GN=PRPF19 PE=1 SV=1 8.25 3318 - 2.17E+06 - - - -2.5827 - 2.097 0.508 - 289.4 1 2 0 -0.0042 14 0 0 0 5.34E+07 5.01E+07 - - - 4.65 1 221125_WJC_METTL3_EV_vs_WT_F03.20131.20131.3 1.49E-08 13/68 K.IDLPAENSNSETIIITGK.R "sp|Q00341|VIGLN_HUMAN,tr|A0A024R4E5|A0A024R4E5_HUMAN,tr|H7BZC3|H7BZC3_HUMAN,tr|H7C2D1|H7C2D1_HUMAN,tr|H0Y394|H0Y394_HUMAN" 5 1913.9946 1.28 35087 20131 3 1913.992954 639.0055 Vigilin OS=Homo sapiens OX=9606 GN=HDLBP PE=1 SV=2 4.14 3318.1 - 1.81E+06 - - - -0.8532 - 2.965 0.548 - 223.9 1 2 0 -0.0016 18 0 0 0 1.05E+07 8.23E+06 - - - 7.3556 1 221125_WJC_METTL3_EV_vs_WT_F03.20132.20132.3 4.26E-06 20/76 R.MVLAAAGGVEHQQLLDLAQK[136.11].H sp|P31930|QCR1_HUMAN 1 2099.1289 1.16 35088 20132 3 2099.126963 700.7169 "Cytochrome b-c1 complex subunit 1, mitochondrial OS=Homo sapiens OX=9606 GN=UQCRC1 PE=1 SV=3" 5.3 3318.2 - 1.59E+06 - - - -0.9037 - 3.888 0.487 - 277.3 1 2 0 -0.0019 20 0 0 0 3.82E+07 3.29E+07 - - - 7.2633 1 221125_WJC_METTL3_EV_vs_WT_F03.20133.20133.2 3.95E-13 19/34 K.IDLPAENSNSETIIITGK[136.11].R "sp|Q00341|VIGLN_HUMAN,tr|A0A024R4E5|A0A024R4E5_HUMAN,tr|H7BZC3|H7BZC3_HUMAN,tr|H7C2D1|H7C2D1_HUMAN,tr|H0Y394|H0Y394_HUMAN" 5 1922.0088 1.43 35089 20133 2 1922.005982 962.0117 Vigilin OS=Homo sapiens OX=9606 GN=HDLBP PE=1 SV=2 4.14 3318.4 - 1.49E+06 - - - -1.4594 - 3.27 0.674 - 774.5 1 2 0 -0.0028 18 0 0 0 1.92E+07 1.34E+07 - - - 6.9311 0.9996 221125_WJC_METTL3_EV_vs_WT_F03.20134.20134.3 4.01E-05 Dec-52 K.ILLAELEQLK[136.11]GQGK.S "sp|P08670|VIME_HUMAN,tr|B0YJC4|B0YJC4_HUMAN,tr|A0A1B0GTT5|A0A1B0GTT5_HUMAN" 3 1546.9174 - 35090 20134 3 1546.915674 516.6464 Vimentin OS=Homo sapiens OX=9606 GN=VIM PE=1 SV=4 6.14 3318.4 - 1.49E+06 - - - -1.1112 - 2.426 0.408 - 152 2 2 1 -0.0017 14 0 0 0 - - - - - 5.3042 1 221125_WJC_METTL3_EV_vs_WT_F03.20136.20136.3 2.97E-07 23/64 R.MEEIVEGC[160.03]TGALHILAR.D "sp|P35222|CTNB1_HUMAN,sp|P14923|PLAK_HUMAN,tr|A0A2R8Y6G0|A0A2R8Y6G0_HUMAN,tr|A0A2R8Y5C3|A0A2R8Y5C3_HUMAN,tr|A0A2R8YCH5|A0A2R8YCH5_HUMAN,tr|A0A2R8Y543|A0A2R8Y543_HUMAN,tr|A0A2R8Y750|A0A2R8Y750_HUMAN,tr|B4DGU4|B4DGU4_HUMAN,tr|A0A2R8Y5A3|A0A2R8Y5A3_HUMAN,tr|A0A2R8Y804|A0A2R8Y804_HUMAN,tr|A0A2R8Y5Z1|A0A2R8Y5Z1_HUMAN,tr|A0A2R8Y7Z0|A0A2R8Y7Z0_HUMAN" 12 1897.939 10.23 35092 20136 3 1897.937335 633.6536 Catenin beta-1 OS=Homo sapiens OX=9606 GN=CTNNB1 PE=1 SV=1 4.75 3318.7 - 1.07E+06 - - - -0.8794 - 3.96 0.652 - 890.2 1 2 0 -0.0017 17 0 0 0 6.26E+07 6.12E+06 - - - 9.2855 0.9981 221125_WJC_METTL3_EV_vs_WT_F03.20137.20137.3 0.0024 16/60 K.LGLPPLTPEQQEALQK.A "sp|Q9UHX1|PUF60_HUMAN,tr|A0A0J9YYL3|A0A0J9YYL3_HUMAN,tr|A0A0J9YWM1|A0A0J9YWM1_HUMAN,tr|H0YEM1|H0YEM1_HUMAN,tr|E9PMU7|E9PMU7_HUMAN,tr|E9PN18|E9PN18_HUMAN,tr|E9PL19|E9PL19_HUMAN,tr|A0A0J9YVR6|A0A0J9YVR6_HUMAN,tr|A0A0J9YXX5|A0A0J9YXX5_HUMAN,tr|A0A0J9YXJ8|A0A0J9YXJ8_HUMAN,tr|E9PQ56|E9PQ56_HUMAN,tr|A0A0J9YVP6|A0A0J9YVP6_HUMAN" 12 1760.9672 1.99 35093 20137 3 1760.963284 587.9964 Poly(U)-binding-splicing factor PUF60 OS=Homo sapiens OX=9606 GN=PUF60 PE=1 SV=1 4.53 3318.8 - 780509 - - - -2.2522 - 1.848 0.294 - 265.9 1 2 0 -0.004 16 0 0 0 2.38E+06 1.20E+06 - - - 3.3924 1 221125_WJC_METTL3_EV_vs_WT_F03.20138.20138.3 0.0089 19/52 R.IWSVPNASC[160.03]VQVVR[166.11].A sp|Q9UMS4|PRP19_HUMAN 1 1623.8431 0.98 35094 20138 3 1623.840272 542.2883 Pre-mRNA-processing factor 19 OS=Homo sapiens OX=9606 GN=PRPF19 PE=1 SV=1 8.25 3318.9 - 611705 - - - -1.7212 - 3.325 0.48 - 600.7 1 2 0 -0.0028 14 0 0 0 1.32E+07 1.35E+07 - - - 7.0837 0.8218 221125_WJC_METTL3_EV_vs_WT_F03.20139.20139.2 2.64E-07 16/24 L.LLAELEQLK[136.11]GQGK[136.11].S "sp|P08670|VIME_HUMAN,tr|B0YJC4|B0YJC4_HUMAN,tr|A0A1B0GTT5|A0A1B0GTT5_HUMAN" 3 1441.8475 2.98 35095 20139 2 1441.843953 721.931 Vimentin OS=Homo sapiens OX=9606 GN=VIM PE=1 SV=4 6.14 3319.1 - 589024 - - - -2.4802 - 3.041 0.436 - 893.2 1 1 1 -0.0036 13 0 0 0 9.12E+06 3.06E+06 - - - 5.1146 0.9999 221125_WJC_METTL3_EV_vs_WT_F03.20142.20142.3 0.000132 Dec-36 R.R[166.11]APFDLFENR[166.11].K sp|P07900|HS90A_HUMAN 1 1283.6526 0.44 35097 20142 3 1283.653382 428.8915 Heat shock protein HSP 90-alpha OS=Homo sapiens OX=9606 GN=HSP90AA1 PE=1 SV=5 6.07 3319.4 - 480083 - - - 0.6404 - 2.471 0.404 - 284.1 1 2 0 0.0008 10 0 0 0 2.56E+06 5.79E+06 - - - 5.6859 0.9998 221125_WJC_METTL3_EV_vs_WT_F03.20144.20144.3 0.000924 14/44 R.ARFEELNADLFR.G "sp|P54652|HSP72_HUMAN,sp|P11142|HSP7C_HUMAN,tr|E9PNE6|E9PNE6_HUMAN,tr|A8K7Q2|A8K7Q2_HUMAN,tr|E9PKE3|E9PKE3_HUMAN,tr|E9PN89|E9PN89_HUMAN" 6 1479.747 0.16 35098 20144 3 1479.746543 494.2563 Heat shock-related 70 kDa protein 2 OS=Homo sapiens OX=9606 GN=HSPA2 PE=1 SV=1 4.68 3319.6 - 1.90E+07 - - - -0.3271 - 2.596 0.466 - 354.6 1 2 1 -0.0005 12 0 0 0 9.63E+08 5.91E+09 - - - 6.3796 0.9895 221125_WJC_METTL3_EV_vs_WT_F03.20145.20145.3 0.101 17/64 R.WLSTSIPEAQWHSSLAR.T "sp|P49327|FAS_HUMAN,tr|A0A0U1RQF0|A0A0U1RQF0_HUMAN" 2 1967.9854 0.56 35099 20145 3 1967.982498 657.0024 Fatty acid synthase OS=Homo sapiens OX=9606 GN=FASN PE=1 SV=3 6.75 3319.7 - 2.56E+06 - - - -1.4543 - 2.037 0.142 - 268.7 1 2 0 -0.0029 17 0 0 0 2.26E+07 4.02E+07 - - - 1.9198 0.9967 221125_WJC_METTL3_EV_vs_WT_F03.20146.20146.2 0.0393 26-Dec K.ILLAELEQLKGQGK.S "sp|P08670|VIME_HUMAN,tr|B0YJC4|B0YJC4_HUMAN,tr|A0A1B0GTT5|A0A1B0GTT5_HUMAN" 3 1538.9032 1.77 35100 20146 2 1538.901138 770.4589 Vimentin OS=Homo sapiens OX=9606 GN=VIM PE=1 SV=4 6.14 3319.7 - 8.65E+06 - - - -1.336 - 2.305 0.392 - 342.6 1 2 1 -0.0021 14 0 0 0 1.01E+08 5.70E+07 - - - 4.0313 1 221125_WJC_METTL3_EV_vs_WT_F03.20148.20148.2 1.32E-08 15/20 K.IEDTVFHVFDK.V "sp|Q9Y2L1|RRP44_HUMAN,tr|G3V1J5|G3V1J5_HUMAN" 2 1348.6663 0.92 35102 20148 2 1348.669197 675.3404 Exosome complex exonuclease RRP44 OS=Homo sapiens OX=9606 GN=DIS3 PE=1 SV=2 4.54 3319.8 - 2.03E+06 - - - 2.1354 - 2.937 0.601 - 908.8 1 2 0 0.0029 11 0 0 0 2.23E+07 2.42E+07 - - - 6.3937 0.9999 221125_WJC_METTL3_EV_vs_WT_F03.20150.20150.2 7.22E-08 16/30 R.VFLQGPAPVGTPSFNR[166.11].Q "sp|Q8IWZ3|ANKH1_HUMAN,tr|H0Y472|H0Y472_HUMAN,tr|H0Y4P6|H0Y4P6_HUMAN,tr|H7C0V5|H7C0V5_HUMAN,tr|H0Y785|H0Y785_HUMAN" 5 1695.8972 1.4 35104 20150 2 1695.898329 848.9559 Ankyrin repeat and KH domain-containing protein 1 OS=Homo sapiens OX=9606 GN=ANKHD1 PE=1 SV=1 9.72 3320.1 - 1.29E+06 - - - 0.6598 - 2.959 0.522 - 739.7 1 2 0 0.0011 16 0 0 0 1.51E+08 1.08E+08 - - - 5.5633 0.9999 221125_WJC_METTL3_EV_vs_WT_F03.20154.20154.2 9.96E-07 14/22 K.LLDSSTVTHLFK[136.11].L "sp|P60900|PSA6_HUMAN,tr|G3V5Z7|G3V5Z7_HUMAN,tr|G3V295|G3V295_HUMAN,tr|G3V3I1|G3V3I1_HUMAN,tr|G3V3U4|G3V3U4_HUMAN" 5 1367.754 0.97 35108 20154 2 1367.755292 684.8843 Proteasome subunit alpha type-6 OS=Homo sapiens OX=9606 GN=PSMA6 PE=1 SV=1 6.74 3320.6 - 586151 - - - 0.9322 - 2.781 0.53 - 556.2 1 2 0 0.0013 12 0 0 0 7.04E+06 7.22E+06 - - - 5.6464 0.9998 221125_WJC_METTL3_EV_vs_WT_F03.20155.20155.2 1.07E-05 26-Aug K.LFGNMEGDC[160.03]PSDWK.T "sp|P02786|TFR1_HUMAN,tr|G3V0E5|G3V0E5_HUMAN" 2 1654.6756 0.8 35109 20155 2 1654.673075 828.3451 Transferrin receptor protein 1 OS=Homo sapiens OX=9606 GN=TFRC PE=1 SV=2 4.03 3320.7 - 480111 - - - -1.5127 - 1.654 0.581 - 131.8 1 2 0 -0.0025 14 0 0 0 2.15E+06 2.67E+06 - - - 4.5942 0.9988 221125_WJC_METTL3_EV_vs_WT_F03.20159.20159.2 0.00447 16/22 R.ARFEELNADLFR.G "sp|P54652|HSP72_HUMAN,sp|P11142|HSP7C_HUMAN,tr|E9PNE6|E9PNE6_HUMAN,tr|A8K7Q2|A8K7Q2_HUMAN,tr|E9PKE3|E9PKE3_HUMAN,tr|E9PN89|E9PN89_HUMAN" 6 1479.747 0.15 35112 20159 2 1479.745989 740.8808 Heat shock-related 70 kDa protein 2 OS=Homo sapiens OX=9606 GN=HSPA2 PE=1 SV=1 4.68 3321 - 6.46E+06 - - - -0.7015 - 2.979 0.44 - 429.5 1 2 1 -0.001 12 0 0 0 1.70E+08 1.10E+09 - - - 5.1627 1 221125_WJC_METTL3_EV_vs_WT_F03.20160.20160.3 9.05E-08 15/60 R.VSLDVNHFAPDELTVK.T "sp|P04792|HSPB1_HUMAN,tr|A0A6Q8PGY2|A0A6Q8PGY2_HUMAN,tr|A0A6Q8PHJ6|A0A6Q8PHJ6_HUMAN,tr|A0A6Q8PHA6|A0A6Q8PHA6_HUMAN,tr|A0A6Q8PF43|A0A6Q8PF43_HUMAN,tr|A0A6Q8PFK8|A0A6Q8PFK8_HUMAN,tr|A0A6Q8PGK1|A0A6Q8PGK1_HUMAN,tr|A0A6Q8PH65|A0A6Q8PH65_HUMAN,tr|A0A6Q8PFE7|A0A6Q8PFE7_HUMAN" 9 1782.9152 2.48 35113 20160 3 1782.914358 595.3123 Heat shock protein beta-1 OS=Homo sapiens OX=9606 GN=HSPB1 PE=1 SV=2 4.54 3321.1 - 6.31E+06 - - - -0.4807 - 3.404 0.615 - 391.3 1 2 0 -0.0009 16 0 0 0 8.42E+08 3.39E+08 - - - 8.5395 0.9998 221125_WJC_METTL3_EV_vs_WT_F03.20161.20161.3 4.18E-06 15/80 K.ADLLLSTQPGR[166.11]EEGSPLELER[166.11].L "sp|P08195|4F2_HUMAN,tr|A0A7P0TAN7|A0A7P0TAN7_HUMAN,tr|J3KPF3|J3KPF3_HUMAN,tr|F5H056|F5H056_HUMAN,tr|F5GZI0|F5GZI0_HUMAN,tr|A0A7P0T9F7|A0A7P0T9F7_HUMAN,tr|A0A7P0TBF8|A0A7P0TBF8_HUMAN,tr|A0A7P0Z4A0|A0A7P0Z4A0_HUMAN,tr|F5GZS6|F5GZS6_HUMAN,tr|A0A7P0Z4P5|A0A7P0Z4P5_HUMAN" 10 2329.2028 1.64 35114 20161 3 2329.20007 777.4082 4F2 cell-surface antigen heavy chain OS=Homo sapiens OX=9606 GN=SLC3A2 PE=1 SV=3 4.25 3321.1 - 3.32E+06 - - - -1.191 - 2.793 0.445 - 223.2 1 2 1 -0.0028 21 0 0 0 4.81E+07 2.93E+07 - - - 5.963 0.8206 221125_WJC_METTL3_EV_vs_WT_F03.20165.20165.3 0.227 Jul-52 K.FLVYVANFDEKDPR.T "sp|P50395|GDIB_HUMAN,tr|Q5SX86|Q5SX86_HUMAN,tr|Q5SX87|Q5SX87_HUMAN" 3 1711.857 3.66 35118 20165 3 1711.857018 571.6263 Rab GDP dissociation inhibitor beta OS=Homo sapiens OX=9606 GN=GDI2 PE=1 SV=2 4.56 3321.4 - 2.10E+06 - - - 0.0269 - 1.212 0.167 - 42.2 1 2 1 0 14 0 0 0 3.21E+07 8.77E+06 - - - 0.9128 0.9995 221125_WJC_METTL3_EV_vs_WT_F03.20166.20166.2 0.0173 20-Nov K.IEDTVFHVFDK[136.11].V "sp|Q9Y2L1|RRP44_HUMAN,tr|G3V1J5|G3V1J5_HUMAN" 2 1356.6805 0.92 35119 20166 2 1356.683334 679.3475 Exosome complex exonuclease RRP44 OS=Homo sapiens OX=9606 GN=DIS3 PE=1 SV=2 4.54 3321.5 - 1.50E+06 - - - 2.0764 - 2.292 0.378 - 498.2 1 2 0 0.0028 11 0 0 0 2.23E+07 2.42E+07 - - - 4.0758 1 221125_WJC_METTL3_EV_vs_WT_F03.20167.20167.3 1.07E-06 14/64 K.FYPLEIDYGQDEEAVK[136.11]K[136.11].L sp|P09874|PARP1_HUMAN 1 2059.0121 0.66 35120 20167 3 2059.009522 687.3446 Poly [ADP-ribose] polymerase 1 OS=Homo sapiens OX=9606 GN=PARP1 PE=1 SV=4 4.18 3321.5 - 1.46E+06 - - - -1.2462 - 2.518 0.539 - 168 1 2 0 -0.0026 17 0 0 0 1.48E+07 2.24E+07 - - - 6.8816 0.9992 221125_WJC_METTL3_EV_vs_WT_F03.20168.20168.2 1.35E-06 14/28 K.NEALAPPLLDAEPAR.G sp|Q10469|MGAT2_HUMAN 1 1575.8257 2.29 35121 20168 2 1575.820108 788.9201 "Alpha-1,6-mannosyl-glycoprotein 2-beta-N-acetylglucosaminyltransferase OS=Homo sapiens OX=9606 GN=MGAT2 PE=1 SV=1" 4.14 3321.7 - 1.21E+06 - - - -3.5302 - 2.591 0.471 - 530.6 1 2 0 -0.0056 15 0 0 0 2.23E+07 9.72E+06 - - - 4.8587 0.9996 221125_WJC_METTL3_EV_vs_WT_F03.20169.20169.3 0.000726 Oct-40 K.LQDMLDGFIK[136.11]K[136.11].F "sp|P55010|IF5_HUMAN,tr|H0YM54|H0YM54_HUMAN,tr|H0YLZ1|H0YLZ1_HUMAN,tr|H0YMJ8|H0YMJ8_HUMAN,tr|H0YN40|H0YN40_HUMAN" 5 1322.7239 1.09 35122 20169 3 1322.722419 441.9152 Eukaryotic translation initiation factor 5 OS=Homo sapiens OX=9606 GN=EIF5 PE=1 SV=2 5.96 3321.8 - 961158 - - - -1.1265 - 1.966 0.321 - 160.1 1 2 0 -0.0015 11 0 0 0 8.28E+06 7.57E+06 - - - 4.0388 0.9995 221125_WJC_METTL3_EV_vs_WT_F03.20173.20173.3 0.000217 Dec-44 R.ARFEELNADLFR[166.11].G "sp|P54652|HSP72_HUMAN,sp|P11142|HSP7C_HUMAN,tr|E9PNE6|E9PNE6_HUMAN,tr|A8K7Q2|A8K7Q2_HUMAN,tr|E9PKE3|E9PKE3_HUMAN,tr|E9PN89|E9PN89_HUMAN" 6 1489.7553 - 35124 20173 3 1489.754566 497.5924 Heat shock-related 70 kDa protein 2 OS=Homo sapiens OX=9606 GN=HSPA2 PE=1 SV=1 4.68 3322.3 - 7.09E+06 - - - -0.4907 - 2.306 0.379 - 278.8 1 2 1 -0.0007 12 0 0 0 - - - - - 5.0812 0.9997 221125_WJC_METTL3_EV_vs_WT_F03.20174.20174.3 4.42E-05 18/76 R.MVLAAAGGVEHQQLLDLAQK.H sp|P31930|QCR1_HUMAN 1 2091.1147 1.16 35125 20174 3 2091.120838 698.0455 "Cytochrome b-c1 complex subunit 1, mitochondrial OS=Homo sapiens OX=9606 GN=UQCRC1 PE=1 SV=3" 5.3 3322.3 - 3.76E+06 - - - 2.9544 - 3.164 0.366 - 255.6 1 2 0 0.0062 20 0 0 0 3.82E+07 3.29E+07 - - - 5.4132 1 221125_WJC_METTL3_EV_vs_WT_F03.20175.20175.3 0.000459 14/60 K.IEVIK[136.11]PGDLGVDLTSK[136.11].L "sp|P38117|ETFB_HUMAN,tr|M0QY67|M0QY67_HUMAN" 2 1698.9739 2.08 35126 20175 3 1698.97012 567.3319 Electron transfer flavoprotein subunit beta OS=Homo sapiens OX=9606 GN=ETFB PE=1 SV=3 4.56 3322.4 - 3.09E+06 - - - -2.1966 - 2.798 0.515 - 144.8 1 2 0 -0.0037 16 0 0 0 7.19E+07 3.45E+07 - - - 6.9207 0.9999 221125_WJC_METTL3_EV_vs_WT_F03.20179.20179.3 0.000642 14/44 K.QLLLSFKPVMQK.F "sp|P78344|IF4G2_HUMAN,tr|H0Y3P2|H0Y3P2_HUMAN,tr|H0YE22|H0YE22_HUMAN,tr|D3DQV9|D3DQV9_HUMAN" 4 1430.8319 1.74 35130 20179 3 1430.83032 477.9513 Eukaryotic translation initiation factor 4 gamma 2 OS=Homo sapiens OX=9606 GN=EIF4G2 PE=1 SV=1 10 3322.7 - 1.43E+06 - - - -1.1343 - 2.286 0.367 - 231.3 1 2 0 -0.0016 12 0 0 0 8.06E+07 4.64E+07 - - - 4.923 0.9999 221125_WJC_METTL3_EV_vs_WT_F03.20180.20180.2 2.47E-06 14/32 R.TAATSVPAYEPLDSLDR.R "sp|Q96T37|RBM15_HUMAN,tr|A0A494C001|A0A494C001_HUMAN,tr|A0A499FJY3|A0A499FJY3_HUMAN,tr|A0A087WWP4|A0A087WWP4_HUMAN" 4 1804.8843 2.96 35131 20180 2 1804.883893 903.4494 RNA-binding protein 15 OS=Homo sapiens OX=9606 GN=RBM15 PE=1 SV=2 4.03 3322.9 - 1.16E+06 - - - -0.2305 - 2.626 0.505 - 283.3 1 2 0 -0.0004 17 0 0 0 4.49E+07 1.52E+07 - - - 5.1444 0.9993 221125_WJC_METTL3_EV_vs_WT_F03.20182.20182.3 0.0015 Nov-40 R.K[136.11]IPLVPENLLK[136.11].K "sp|Q6DKI1|RL7L_HUMAN,tr|R4GMU7|R4GMU7_HUMAN" 2 1278.8246 1.19 35133 20182 3 1278.823773 427.2821 60S ribosomal protein L7-like 1 OS=Homo sapiens OX=9606 GN=RPL7L1 PE=1 SV=2 8.59 3323.1 - 855539 - - - -0.6537 - 1.667 0.32 - 195.4 1 2 0 -0.0008 11 0 0 0 1.38E+07 1.16E+07 - - - 3.5592 0.9998 221125_WJC_METTL3_EV_vs_WT_F03.20183.20183.2 0.00015 22-Dec K.QVIINLVDQAGR[166.11].E "sp|Q9Y2H2|SAC2_HUMAN,tr|A0A3B3ISI3|A0A3B3ISI3_HUMAN,tr|A0A3B3IRJ9|A0A3B3IRJ9_HUMAN,tr|A0A3B3ITL0|A0A3B3ITL0_HUMAN,tr|A0A3B3ITR9|A0A3B3ITR9_HUMAN,tr|A0A3B3ISJ5|A0A3B3ISJ5_HUMAN" 6 1334.7546 0.75 35134 20183 2 1334.752776 668.3846 Phosphatidylinositide phosphatase SAC2 OS=Homo sapiens OX=9606 GN=INPP5F PE=1 SV=3 5.84 3323.3 - 687876 - - - -1.3433 - 2.245 0.426 - 557.2 1 2 0 -0.0018 12 0 0 0 2.53E+06 3.37E+06 - - - 4.3147 1 221125_WJC_METTL3_EV_vs_WT_F03.20187.20187.3 0.000159 13/44 K.LLDSSTVTHLFK.L "sp|P60900|PSA6_HUMAN,tr|G3V5Z7|G3V5Z7_HUMAN,tr|G3V295|G3V295_HUMAN,tr|G3V3I1|G3V3I1_HUMAN,tr|G3V3U4|G3V3U4_HUMAN" 5 1359.7398 0.7 35137 20187 3 1359.737073 454.2539 Proteasome subunit alpha type-6 OS=Homo sapiens OX=9606 GN=PSMA6 PE=1 SV=1 6.74 3323.6 - 4.67E+06 - - - -2.018 - 2.822 0.477 - 223.8 1 2 0 -0.0027 12 0 0 0 5.69E+07 8.14E+07 - - - 6.733 0.9999 221125_WJC_METTL3_EV_vs_WT_F03.20188.20188.2 5.23E-07 13/24 K.GVEGLIDIENPNR.V sp|Q13442|HAP28_HUMAN 1 1424.726 0.76 35138 20188 2 1424.72368 713.3703 28 kDa heat- and acid-stable phosphoprotein OS=Homo sapiens OX=9606 GN=PDAP1 PE=1 SV=1 4.14 3323.6 - 2.94E+06 - - - -1.5982 - 2.85 0.531 - 663.3 1 2 0 -0.0023 13 0 0 0 3.49E+07 4.60E+07 - - - 5.6502 1 221125_WJC_METTL3_EV_vs_WT_F03.20190.20190.2 4.82E-10 23/30 R.VSLDVNHFAPDELTVK.T "sp|P04792|HSPB1_HUMAN,tr|A0A6Q8PGY2|A0A6Q8PGY2_HUMAN,tr|A0A6Q8PHJ6|A0A6Q8PHJ6_HUMAN,tr|A0A6Q8PHA6|A0A6Q8PHA6_HUMAN,tr|A0A6Q8PF43|A0A6Q8PF43_HUMAN,tr|A0A6Q8PFK8|A0A6Q8PFK8_HUMAN,tr|A0A6Q8PGK1|A0A6Q8PGK1_HUMAN,tr|A0A6Q8PH65|A0A6Q8PH65_HUMAN,tr|A0A6Q8PFE7|A0A6Q8PFE7_HUMAN" 9 1782.9152 2.57 35140 20190 2 1782.913062 892.4649 Heat shock protein beta-1 OS=Homo sapiens OX=9606 GN=HSPB1 PE=1 SV=2 4.54 3323.9 - 1.63E+06 - - - -1.2076 - 4.639 0.676 - 2256.1 1 2 0 -0.0022 16 0 0 0 4.45E+07 1.73E+07 - - - 7.8059 0.9993 221125_WJC_METTL3_EV_vs_WT_F03.20195.20195.3 0.00621 Oct-36 K.DRPFFAGLVK.Y "sp|P15531|NDKA_HUMAN,tr|Q32Q12|Q32Q12_HUMAN,tr|J3KPD9|J3KPD9_HUMAN,tr|E5RHP0|E5RHP0_HUMAN,tr|E7ERL0|E7ERL0_HUMAN" 5 1148.6342 1.37 35143 20195 3 1148.631823 383.8854 Nucleoside diphosphate kinase A OS=Homo sapiens OX=9606 GN=NME1 PE=1 SV=1 8.75 3324.5 - 4.23E+06 - - - -2.0947 - 1.949 0.324 - 138.4 1 2 0 -0.0024 10 0 0 0 2.12E+08 1.54E+08 - - - 4.1005 0.9996 221125_WJC_METTL3_EV_vs_WT_F03.20196.20196.3 0.000795 18/80 K.ADLLLSTQPGREEGSPLELER.L "sp|P08195|4F2_HUMAN,tr|A0A7P0TAN7|A0A7P0TAN7_HUMAN,tr|J3KPF3|J3KPF3_HUMAN,tr|F5H056|F5H056_HUMAN,tr|F5GZI0|F5GZI0_HUMAN,tr|A0A7P0T9F7|A0A7P0T9F7_HUMAN,tr|A0A7P0TBF8|A0A7P0TBF8_HUMAN,tr|A0A7P0Z4A0|A0A7P0Z4A0_HUMAN,tr|F5GZS6|F5GZS6_HUMAN,tr|A0A7P0Z4P5|A0A7P0Z4P5_HUMAN" 10 2309.1863 1.64 35144 20196 3 2309.184821 770.736 4F2 cell-surface antigen heavy chain OS=Homo sapiens OX=9606 GN=SLC3A2 PE=1 SV=3 4.25 3324.5 - 4.71E+06 - - - -0.6422 - 3.025 0.364 - 311.3 1 2 1 -0.0015 21 0 0 0 4.81E+07 2.93E+07 - - - 5.2516 1 221125_WJC_METTL3_EV_vs_WT_F03.20198.20198.2 1.89E-08 14/26 K.TDFFIGGEEGMAEK.L "sp|Q9Y266|NUDC_HUMAN,tr|A0A0A0MSU9|A0A0A0MSU9_HUMAN" 2 1529.6708 1.97 35146 20198 2 1529.670108 765.8427 Nuclear migration protein nudC OS=Homo sapiens OX=9606 GN=NUDC PE=1 SV=1 4 3324.8 - 2.12E+06 - - - -0.4589 - 2.768 0.658 - 562.3 1 2 0 -0.0007 14 0 0 0 4.73E+07 2.40E+07 - - - 6.4557 0.9984 221125_WJC_METTL3_EV_vs_WT_F03.20200.20200.2 0.2 18-Dec K.DR[166.11]PFFAGLVK[136.11].Y "sp|P15531|NDKA_HUMAN,tr|Q32Q12|Q32Q12_HUMAN,tr|J3KPD9|J3KPD9_HUMAN,tr|E5RHP0|E5RHP0_HUMAN,tr|E7ERL0|E7ERL0_HUMAN" 5 1166.6567 1.5 35148 20200 2 1166.65427 584.3356 Nucleoside diphosphate kinase A OS=Homo sapiens OX=9606 GN=NME1 PE=1 SV=1 8.75 3325 - 1.88E+06 - - - -2.082 - 2.091 0.218 - 353.7 1 2 0 -0.0024 10 0 0 0 1.32E+08 8.81E+07 - - - 2.7094 1 221125_WJC_METTL3_EV_vs_WT_F03.20201.20201.3 3.16E-09 17/52 K.GYAWGLNELK[136.11]PISK[136.11].G sp|P33908|MA1A1_HUMAN 1 1590.8741 3.74 35149 20201 3 1590.876806 531.2986 "Mannosyl-oligosaccharide 1,2-alpha-mannosidase IA OS=Homo sapiens OX=9606 GN=MAN1A1 PE=1 SV=3" 8.5 3325.2 - 1.66E+06 - - - 1.7142 - 2.965 0.574 - 310.5 1 2 0 0.0027 14 0 0 0 3.97E+07 1.06E+07 - - - 7.8272 0.9836 221125_WJC_METTL3_EV_vs_WT_F03.20203.20203.2 8.96E-06 15/28 Y.AGYPSQFVPGLDPSK[136.11].S sp|Q9H7S9|ZN703_HUMAN 1 1569.7919 1.65 35151 20203 2 1569.788745 785.9032 Zinc finger protein 703 OS=Homo sapiens OX=9606 GN=ZNF703 PE=1 SV=1 5.88 3325.4 - 1.34E+06 - - - -1.9837 - 2.387 0.481 - 499.4 1 1 0 -0.0031 15 0 0 0 3.53E+07 2.13E+07 - - - 4.7317 1 221125_WJC_METTL3_EV_vs_WT_F03.20204.20204.2 3.72E-08 16/32 R.TAATSVPAYEPLDSLDR[166.11].R "sp|Q96T37|RBM15_HUMAN,tr|A0A494C001|A0A494C001_HUMAN,tr|A0A499FJY3|A0A499FJY3_HUMAN,tr|A0A087WWP4|A0A087WWP4_HUMAN" 4 1814.8926 2.56 35152 20204 2 1814.894171 908.4536 RNA-binding protein 15 OS=Homo sapiens OX=9606 GN=RBM15 PE=1 SV=2 4.03 3325.5 - 1.25E+06 - - - 0.8772 - 2.985 0.603 - 411.9 1 2 0 0.0016 17 0 0 0 3.82E+07 1.49E+07 - - - 6.1829 1 221125_WJC_METTL3_EV_vs_WT_F03.20210.20210.3 6.59E-07 13/60 R.VSLDVNHFAPDELTVK[136.11].T "sp|P04792|HSPB1_HUMAN,tr|A0A6Q8PGY2|A0A6Q8PGY2_HUMAN,tr|A0A6Q8PHJ6|A0A6Q8PHJ6_HUMAN,tr|A0A6Q8PHA6|A0A6Q8PHA6_HUMAN,tr|A0A6Q8PF43|A0A6Q8PF43_HUMAN,tr|A0A6Q8PFK8|A0A6Q8PFK8_HUMAN,tr|A0A6Q8PGK1|A0A6Q8PGK1_HUMAN,tr|A0A6Q8PH65|A0A6Q8PH65_HUMAN,tr|A0A6Q8PFE7|A0A6Q8PFE7_HUMAN" 9 1790.9294 2.49 35156 20210 3 1790.92431 597.9837 Heat shock protein beta-1 OS=Homo sapiens OX=9606 GN=HSPB1 PE=1 SV=2 4.54 3326.3 - 4.95E+07 - - - -2.8505 - 3.046 0.554 - 264.4 1 2 0 -0.0051 16 0 0 0 8.45E+08 3.39E+08 - - - 7.5731 1 221125_WJC_METTL3_EV_vs_WT_F03.20211.20211.3 0.0296 13/44 K.QLLLSFK[136.11]PVMQK[136.11].F "sp|P78344|IF4G2_HUMAN,tr|H0Y3P2|H0Y3P2_HUMAN,tr|H0YE22|H0YE22_HUMAN,tr|D3DQV9|D3DQV9_HUMAN" 4 1446.8603 1.74 35157 20211 3 1446.858776 483.2941 Eukaryotic translation initiation factor 4 gamma 2 OS=Homo sapiens OX=9606 GN=EIF4G2 PE=1 SV=1 10 3326.3 - 6.35E+06 - - - -1.083 - 2.45 0.448 - 175.4 1 2 0 -0.0016 12 0 0 0 8.06E+07 4.64E+07 - - - 6.0181 0.9996 221125_WJC_METTL3_EV_vs_WT_F03.20212.20212.3 0.00286 Dec-36 K.DR[166.11]PFFAGLVK[136.11].Y "sp|P15531|NDKA_HUMAN,tr|Q32Q12|Q32Q12_HUMAN,tr|J3KPD9|J3KPD9_HUMAN,tr|E5RHP0|E5RHP0_HUMAN,tr|E7ERL0|E7ERL0_HUMAN" 5 1166.6567 1.37 35158 20212 3 1166.654757 389.8928 Nucleoside diphosphate kinase A OS=Homo sapiens OX=9606 GN=NME1 PE=1 SV=1 8.75 3326.4 - 8.56E+06 - - - -1.6646 - 2.01 0.331 - 168 1 2 0 -0.0019 10 0 0 0 2.12E+08 1.54E+08 - - - 4.2686 1 221125_WJC_METTL3_EV_vs_WT_F03.20213.20213.2 9.96E-09 20-Nov K.NNLEALEDFEK.A "sp|P31025|LCN1_HUMAN,sp|Q5VSP4|LC1L1_HUMAN" 2 1320.6198 8.49 35159 20213 2 1320.61563 661.3172 Lipocalin-1 OS=Homo sapiens OX=9606 GN=LCN1 PE=1 SV=1 4 3326.4 - 7.56E+06 - - - -3.1281 - 2.398 0.61 - 518.6 1 2 0 -0.0041 11 0 0 0 6.18E+07 7.28E+06 - - - 5.9113 0.9997 221125_WJC_METTL3_EV_vs_WT_F03.20214.20214.3 0.00301 Sep-48 K.AVLWQDSFSPHLK[136.11].H "sp|Q14671|PUM1_HUMAN,tr|Q5T1Z8|Q5T1Z8_HUMAN,tr|E9PM68|E9PM68_HUMAN,tr|E9PMX1|E9PMX1_HUMAN,tr|H0YEH2|H0YEH2_HUMAN,tr|Q5T1Z4|Q5T1Z4_HUMAN,tr|E9PL65|E9PL65_HUMAN,tr|E9PR38|E9PR38_HUMAN" 8 1534.8024 2.26 35160 20214 3 1534.799881 512.6081 Pumilio homolog 1 OS=Homo sapiens OX=9606 GN=PUM1 PE=1 SV=3 6.79 3326.4 - 5.53E+06 - - - -1.6178 - 1.968 0.371 - 97.9 1 2 0 -0.0025 13 0 0 0 1.63E+08 7.22E+07 - - - 4.5112 0.9999 221125_WJC_METTL3_EV_vs_WT_F03.20215.20215.3 0.000168 16/52 K.GYAWGLNELKPISK.G sp|P33908|MA1A1_HUMAN 1 1574.8457 3.86 35161 20215 3 1574.842729 525.9558 "Mannosyl-oligosaccharide 1,2-alpha-mannosidase IA OS=Homo sapiens OX=9606 GN=MAN1A1 PE=1 SV=3" 8.5 3326.5 - 3.91E+06 - - - -1.8732 - 2.599 0.404 - 262.8 1 2 0 -0.0029 14 0 0 0 4.49E+07 1.16E+07 - - - 5.5817 1 221125_WJC_METTL3_EV_vs_WT_F03.20217.20217.3 0.00192 17/44 R.DISLDSELHDLR[166.11].L "sp|Q15643|TRIPB_HUMAN,tr|H0YJ97|H0YJ97_HUMAN" 2 1421.7026 1.26 35163 20217 3 1421.701464 474.9081 Thyroid receptor-interacting protein 11 OS=Homo sapiens OX=9606 GN=TRIP11 PE=1 SV=3 4.22 3326.7 - 2.26E+06 - - - -0.7941 - 2.563 0.444 - 282.3 1 2 0 -0.0011 12 0 0 0 1.49E+08 1.18E+08 - - - 6.0987 1 221125_WJC_METTL3_EV_vs_WT_F03.20218.20218.2 2.30E-07 15/28 K.QAPLSQSDITILTPK[136.11].L "sp|P39880|CUX1_HUMAN,tr|A0A2R8Y852|A0A2R8Y852_HUMAN,tr|A0A2R8YDI1|A0A2R8YDI1_HUMAN" 3 1618.9021 1.51 35164 20218 2 1618.902036 810.4583 Homeobox protein cut-like 1 OS=Homo sapiens OX=9606 GN=CUX1 PE=1 SV=3 5.84 3326.8 - 2.09E+06 - - - -0.0624 - 2.852 0.598 - 619.3 1 2 0 -0.0001 15 0 0 0 8.75E+07 5.78E+07 - - - 6.0344 1 221125_WJC_METTL3_EV_vs_WT_F03.20219.20219.2 1.69E-06 15/28 K.QAPLSQSDITILTPK.L "sp|P39880|CUX1_HUMAN,tr|A0A2R8Y852|A0A2R8Y852_HUMAN,tr|A0A2R8YDI1|A0A2R8YDI1_HUMAN" 3 1610.8879 1.51 35165 20219 2 1610.887539 806.4512 Homeobox protein cut-like 1 OS=Homo sapiens OX=9606 GN=CUX1 PE=1 SV=3 5.84 3326.9 - 1.93E+06 - - - -0.2471 - 2.903 0.607 - 596.2 1 2 0 -0.0004 15 0 0 0 8.75E+07 5.78E+07 - - - 6.1444 1 221125_WJC_METTL3_EV_vs_WT_F03.20220.20220.2 2.36E-08 19/32 K.TTSEIFLSSTAEGADLR.T "sp|Q8IWZ3|ANKH1_HUMAN,tr|E9PDP5|E9PDP5_HUMAN,tr|D6RHC4|D6RHC4_HUMAN" 3 1796.8792 1.19 35166 20220 2 1796.880512 899.4469 Ankyrin repeat and KH domain-containing protein 1 OS=Homo sapiens OX=9606 GN=ANKHD1 PE=1 SV=1 4.14 3327.1 - 1.85E+06 - - - 0.7174 - 3.39 0.616 - 1149.4 1 2 0 0.0013 17 0 0 0 6.31E+07 5.30E+07 - - - 6.5918 0.9999 221125_WJC_METTL3_EV_vs_WT_F03.20224.20224.3 1.91E-06 17/60 R.AAEEFVNVYYTTMDKR.R sp|Q9UKK6|NXT1_HUMAN 1 1935.9037 0.85 35170 20224 3 1935.897043 646.3085 NTF2-related export protein 1 OS=Homo sapiens OX=9606 GN=NXT1 PE=1 SV=1 4.68 3327.6 - 1.00E+06 - - - -3.4201 - 3.287 0.482 - 393.6 1 2 0 -0.0066 16 0 0 0 6.14E+06 7.20E+06 - - - 6.9653 0.9997 221125_WJC_METTL3_EV_vs_WT_F03.20225.20225.3 0.000733 Oct-36 R.R[166.11]FDAMPFTLR[166.11].A sp|Q9UQ80|PA2G4_HUMAN 1 1272.6552 0.03 35171 20225 3 1272.65371 425.2257 Proliferation-associated protein 2G4 OS=Homo sapiens OX=9606 GN=PA2G4 PE=1 SV=3 9.6 3327.7 - 993342 - - - -1.1731 - 2.013 0.333 - 228.9 1 2 0 -0.0015 10 0 0 0 1.95E+05 6.73E+06 - - - 4.2954 0.9986 221125_WJC_METTL3_EV_vs_WT_F03.20227.20227.3 0.000549 Nov-40 R.KIPLVPENLLK.K "sp|Q6DKI1|RL7L_HUMAN,tr|R4GMU7|R4GMU7_HUMAN" 2 1262.7962 1.21 35173 20227 3 1262.795633 421.9393 60S ribosomal protein L7-like 1 OS=Homo sapiens OX=9606 GN=RPL7L1 PE=1 SV=2 8.59 3328 - 662728 - - - -0.4561 - 1.95 0.238 - 269.4 1 2 0 -0.0006 11 0 0 0 1.31E+07 1.09E+07 - - - 3.0905 0.8647 221125_WJC_METTL3_EV_vs_WT_F03.20230.20230.2 0.866 20-Aug K.NQILNLTTDNA.N "sp|P13645|K1C10_HUMAN,tr|A0A1B0GVI3|A0A1B0GVI3_HUMAN" 2 1215.6095 - 35174 20230 2 1215.608162 608.812 "Keratin, type I cytoskeletal 10 OS=Homo sapiens OX=9606 GN=KRT10 PE=1 SV=6" 3.8 3328.4 - 5.28E+06 - - - -1.1262 - 1.517 0.217 - 214.1 1 1 0 -0.0014 11 0 0 0 - - - - - 1.7707 1 221125_WJC_METTL3_EV_vs_WT_F03.20231.20231.2 1.19E-14 21/32 K.MLQAPESVLAEHYQDLR.R "sp|O00746|NDKM_HUMAN,tr|Q4TT34|Q4TT34_HUMAN,tr|H0Y6J0|H0Y6J0_HUMAN,tr|F2Z2X0|F2Z2X0_HUMAN,tr|A2IDC9|A2IDC9_HUMAN" 5 1998.9833 2.29 35175 20231 2 1998.983107 1000.4989 "Nucleoside diphosphate kinase, mitochondrial OS=Homo sapiens OX=9606 GN=NME4 PE=1 SV=1" 4.65 3328.4 - 5.50E+06 - - - -0.1021 - 3.843 0.714 - 1308.7 1 2 0 -0.0002 17 0 0 0 5.02E+07 2.19E+07 - - - 7.6244 1 221125_WJC_METTL3_EV_vs_WT_F03.20232.20232.2 3.54E-11 20/32 K.TTSEIFLSSTAEGADLR[166.11].T "sp|Q8IWZ3|ANKH1_HUMAN,tr|E9PDP5|E9PDP5_HUMAN,tr|D6RHC4|D6RHC4_HUMAN" 3 1806.8875 1.19 35176 20232 2 1806.884937 904.451 Ankyrin repeat and KH domain-containing protein 1 OS=Homo sapiens OX=9606 GN=ANKHD1 PE=1 SV=1 4.14 3328.5 - 4.22E+06 - - - -1.4146 - 3.597 0.686 - 1047.6 1 2 0 -0.0026 17 0 0 0 6.31E+07 5.30E+07 - - - 7.2542 0.9994 221125_WJC_METTL3_EV_vs_WT_F03.20233.20233.3 0.00424 13/60 R.VFLQGPAPVGTPSFNR[166.11].Q "sp|Q8IWZ3|ANKH1_HUMAN,tr|H0Y472|H0Y472_HUMAN,tr|H0Y4P6|H0Y4P6_HUMAN,tr|H7C0V5|H7C0V5_HUMAN,tr|H0Y785|H0Y785_HUMAN" 5 1695.8972 1.99 35177 20233 3 1695.903963 566.3063 Ankyrin repeat and KH domain-containing protein 1 OS=Homo sapiens OX=9606 GN=ANKHD1 PE=1 SV=1 9.72 3328.6 - 4.08E+06 - - - 3.982 - 2.57 0.401 - 202.8 1 2 0 0.0068 16 0 0 0 8.94E+07 4.50E+07 - - - 5.4308 1 221125_WJC_METTL3_EV_vs_WT_F03.20235.20235.2 3.73E-09 14/26 K.TDFFIGGEEGMAEK[136.11].L "sp|Q9Y266|NUDC_HUMAN,tr|A0A0A0MSU9|A0A0A0MSU9_HUMAN" 2 1537.685 1.92 35179 20235 2 1537.683387 769.8498 Nuclear migration protein nudC OS=Homo sapiens OX=9606 GN=NUDC PE=1 SV=1 4 3328.7 - 3.51E+06 - - - -1.0555 - 2.817 0.619 - 478.6 1 2 0 -0.0016 14 0 0 0 4.62E+07 2.40E+07 - - - 6.2114 1 221125_WJC_METTL3_EV_vs_WT_F03.20237.20237.3 8.80E-06 17/52 K.IRPGFEEQILYLQK.Q "sp|Q8IWJ2|GCC2_HUMAN,tr|B8ZZA5|B8ZZA5_HUMAN,tr|B8ZZW2|B8ZZW2_HUMAN" 3 1732.9512 2.49 35181 20237 3 1732.952457 578.6577 GRIP and coiled-coil domain-containing protein 2 OS=Homo sapiens OX=9606 GN=GCC2 PE=1 SV=4 6.14 3328.8 - 2.38E+06 - - - 0.7219 - 3.046 0.472 - 350.1 1 2 0 0.0013 14 0 0 0 1.13E+07 4.54E+06 - - - 6.762 1 221125_WJC_METTL3_EV_vs_WT_F03.20238.20238.3 5.47E-12 29/96 R.IITGGAPELAVEGNGPVESNAVLTK.A "sp|Q12996|CSTF3_HUMAN,tr|H0YE74|H0YE74_HUMAN,tr|E9PLP8|E9PLP8_HUMAN" 3 2435.2908 2.34 35182 20238 3 2435.290514 812.7709 Cleavage stimulation factor subunit 3 OS=Homo sapiens OX=9606 GN=CSTF3 PE=1 SV=1 4.25 3329 - 2.36E+06 - - - -0.1051 - 4.73 0.653 - 853.3 1 2 0 -0.0003 25 0 0 0 2.67E+07 1.14E+07 - - - 9.3953 1 221125_WJC_METTL3_EV_vs_WT_F03.20239.20239.2 5.54E-08 18/32 K.MLQAPESVLAEHYQDLR[166.11].R "sp|O00746|NDKM_HUMAN,tr|Q4TT34|Q4TT34_HUMAN,tr|H0Y6J0|H0Y6J0_HUMAN,tr|F2Z2X0|F2Z2X0_HUMAN,tr|A2IDC9|A2IDC9_HUMAN" 5 2008.9916 2.29 35183 20239 2 2008.988281 1005.5031 "Nucleoside diphosphate kinase, mitochondrial OS=Homo sapiens OX=9606 GN=NME4 PE=1 SV=1" 4.65 3329.1 - 2.33E+06 - - - -1.6426 - 3.676 0.577 - 809.1 1 2 0 -0.0033 17 0 0 0 5.02E+07 2.19E+07 - - - 6.5023 1 221125_WJC_METTL3_EV_vs_WT_F03.20240.20240.2 1.22E-08 23/36 R.ILSAENIPNLPPGGGLAGK.R "sp|O75688|PPM1B_HUMAN,tr|B8ZZF0|B8ZZF0_HUMAN,tr|A0A3B3IS24|A0A3B3IS24_HUMAN,tr|C9JIR6|C9JIR6_HUMAN" 4 1817.0047 3.7 35184 20240 2 1817.007057 909.5096 Protein phosphatase 1B OS=Homo sapiens OX=9606 GN=PPM1B PE=1 SV=1 6 3329.2 - 2.29E+06 - - - 1.2977 - 3.565 0.586 - 986.6 1 2 0 0.0024 19 0 0 0 9.76E+07 2.63E+07 - - - 6.4937 1 221125_WJC_METTL3_EV_vs_WT_F03.20241.20241.2 1.96E-05 15/22 R.DISLDSELHDLR.L "sp|Q15643|TRIPB_HUMAN,tr|H0YJ97|H0YJ97_HUMAN" 2 1411.6943 1.51 35185 20241 2 1411.690967 706.8544 Thyroid receptor-interacting protein 11 OS=Homo sapiens OX=9606 GN=TRIP11 PE=1 SV=3 4.22 3329.4 - 2.23E+06 - - - -2.3773 - 2.839 0.548 - 707.4 1 2 0 -0.0034 12 0 0 0 2.59E+07 1.72E+07 - - - 5.833 1 221125_WJC_METTL3_EV_vs_WT_F03.20242.20242.2 6.08E-08 20/30 R.VSLDVNHFAPDELTVK[136.11].T "sp|P04792|HSPB1_HUMAN,tr|A0A6Q8PGY2|A0A6Q8PGY2_HUMAN,tr|A0A6Q8PHJ6|A0A6Q8PHJ6_HUMAN,tr|A0A6Q8PHA6|A0A6Q8PHA6_HUMAN,tr|A0A6Q8PF43|A0A6Q8PF43_HUMAN,tr|A0A6Q8PFK8|A0A6Q8PFK8_HUMAN,tr|A0A6Q8PGK1|A0A6Q8PGK1_HUMAN,tr|A0A6Q8PH65|A0A6Q8PH65_HUMAN,tr|A0A6Q8PFE7|A0A6Q8PFE7_HUMAN" 9 1790.9294 2.57 35186 20242 2 1790.929669 896.472 Heat shock protein beta-1 OS=Homo sapiens OX=9606 GN=HSPB1 PE=1 SV=2 4.54 3329.5 - 2.09E+06 - - - 0.1418 - 4.181 0.622 - 1704.2 1 2 0 0.0003 16 0 0 0 4.45E+07 1.73E+07 - - - 7.1521 1 221125_WJC_METTL3_EV_vs_WT_F03.20243.20243.2 6.75E-11 15/28 R.YSQTGNYELAVALSR.W "sp|P39656|OST48_HUMAN,tr|A0A0C4DGS1|A0A0C4DGS1_HUMAN" 2 1670.8264 1.25 35187 20243 2 1670.82157 836.4205 Dolichyl-diphosphooligosaccharide--protein glycosyltransferase 48 kDa subunit OS=Homo sapiens OX=9606 GN=DDOST PE=1 SV=4 6 3329.6 - 2.00E+06 - - - -2.8908 - 3.251 0.68 - 830 1 2 0 -0.0048 15 0 0 0 1.66E+07 1.33E+07 - - - 6.9605 0.9951 221125_WJC_METTL3_EV_vs_WT_F03.20245.20245.2 5.75E-07 13/24 L.SVETDYTFPLAEK[136.11].V "sp|P05388|RLA0_HUMAN,tr|F8VWS0|F8VWS0_HUMAN,tr|F8W1K8|F8W1K8_HUMAN,tr|F8VW21|F8VW21_HUMAN,tr|F8VZS0|F8VZS0_HUMAN" 5 1506.7333 0.1 35189 20245 2 1506.73289 754.3739 60S acidic ribosomal protein P0 OS=Homo sapiens OX=9606 GN=RPLP0 PE=1 SV=1 4.14 3329.9 - 1.86E+06 - - - -0.2993 - 2.551 0.578 - 387.7 1 1 0 -0.0004 13 0 0 0 1.60E+06 1.60E+07 - - - 5.7135 1 221125_WJC_METTL3_EV_vs_WT_F03.20246.20246.2 1.48E-08 14/26 R.QASPSIVIALAGNK[136.11].A sp|P61020|RAB5B_HUMAN 1 1375.7915 1.04 35190 20246 2 1375.7876 688.903 Ras-related protein Rab-5B OS=Homo sapiens OX=9606 GN=RAB5B PE=1 SV=1 8.75 3330 - 1.65E+06 - - - -2.8093 - 2.855 0.577 - 826.9 1 2 0 -0.0039 14 0 0 0 1.42E+07 1.37E+07 - - - 5.9341 0.9999 221125_WJC_METTL3_EV_vs_WT_F03.20249.20249.3 4.28E-06 18/56 K.GHAVNLLDVPVPVAR[166.11].K sp|O00429|DNM1L_HUMAN 1 1565.8917 0.73 35193 20249 3 1565.892677 522.9712 Dynamin-1-like protein OS=Homo sapiens OX=9606 GN=DNM1L PE=1 SV=2 6.74 3330.4 - 1.15E+06 - - - 0.6041 - 2.381 0.44 - 394.5 1 2 0 0.0009 15 0 0 0 7.02E+06 9.57E+06 - - - 5.709 1 221125_WJC_METTL3_EV_vs_WT_F03.20251.20251.2 4.91E-11 18/28 K.GYGFVDFDSPSAAQK.A "sp|Q15434|RBMS2_HUMAN,tr|F8W1T6|F8W1T6_HUMAN" 2 1587.7205 1.53 35194 20251 2 1587.716168 794.8675 "RNA-binding motif, single-stranded-interacting protein 2 OS=Homo sapiens OX=9606 GN=RBMS2 PE=1 SV=1" 4.21 3330.7 - 3.16E+06 - - - -2.7524 - 3.48 0.714 - 1264.3 1 2 0 -0.0044 15 0 0 0 7.24E+07 4.72E+07 - - - 7.3791 0.9996 221125_WJC_METTL3_EV_vs_WT_F03.20252.20252.3 0.00917 Dec-48 K.QLLGEHLTAILQK[136.11].G "sp|Q13619|CUL4A_HUMAN,sp|Q13620|CUL4B_HUMAN,tr|A0A7P0T8P8|A0A7P0T8P8_HUMAN,tr|A0A7P0T9D0|A0A7P0T9D0_HUMAN,tr|A0A669KAX4|A0A669KAX4_HUMAN,tr|A0A0A0MR50|A0A0A0MR50_HUMAN,tr|K4DI93|K4DI93_HUMAN,tr|A0A804CL36|A0A804CL36_HUMAN,tr|A0A7P0T9C8|A0A7P0T9C8_HUMAN,tr|A0A7P0T954|A0A7P0T954_HUMAN,tr|A0A7P0T9P5|A0A7P0T9P5_HUMAN,tr|A0A669KBG9|A0A669KBG9_HUMAN,tr|A0A7P0TAF9|A0A7P0TAF9_HUMAN,tr|A0A7P0T9L3|A0A7P0T9L3_HUMAN,tr|A0A7P0TAQ3|A0A7P0TAQ3_HUMAN" 15 1470.865 0.8 35195 20252 3 1470.863597 491.2956 Cullin-4A OS=Homo sapiens OX=9606 GN=CUL4A PE=1 SV=3 6.75 3330.9 - 589248 - - - -0.9294 - 2.266 0.288 - 179.2 1 2 0 -0.0014 13 0 0 0 3.59E+06 4.51E+06 - - - 3.9684 1 221125_WJC_METTL3_EV_vs_WT_F03.20254.20254.2 1.36E-05 17/26 R.GVVDSEDIPLNLSR[166.11].E "sp|Q12931|TRAP1_HUMAN,sp|P08238|HS90B_HUMAN,sp|Q58FF7|H90B3_HUMAN,sp|P07900|HS90A_HUMAN,tr|I3L0K7|I3L0K7_HUMAN,tr|I3L239|I3L239_HUMAN" 6 1522.7867 0.82 35197 20254 2 1522.784176 762.4006 "Heat shock protein 75 kDa, mitochondrial OS=Homo sapiens OX=9606 GN=TRAP1 PE=1 SV=3" 4.03 3330.9 - 1.30E+07 - - - -1.6292 - 3.349 0.606 - 897.8 1 2 0 -0.0025 14 0 0 0 5.72E+08 6.94E+08 - - - 6.5492 1 221125_WJC_METTL3_EV_vs_WT_F03.20256.20256.2 4.60E-10 15/26 R.GVVDSEDIPLNLSR.E "sp|Q12931|TRAP1_HUMAN,sp|P08238|HS90B_HUMAN,sp|Q58FF7|H90B3_HUMAN,sp|P07900|HS90A_HUMAN,tr|I3L0K7|I3L0K7_HUMAN,tr|I3L239|I3L239_HUMAN" 6 1512.7784 0.82 35199 20256 2 1512.776757 757.3965 "Heat shock protein 75 kDa, mitochondrial OS=Homo sapiens OX=9606 GN=TRAP1 PE=1 SV=3" 4.03 3331 - 1.06E+07 - - - -1.0775 - 2.963 0.651 - 649 1 2 0 -0.0016 14 0 0 0 5.72E+08 6.94E+08 - - - 6.5745 0.9999 221125_WJC_METTL3_EV_vs_WT_F03.20257.20257.3 5.84E-05 16/72 R.ILSAENIPNLPPGGGLAGK.R "sp|O75688|PPM1B_HUMAN,tr|B8ZZF0|B8ZZF0_HUMAN,tr|A0A3B3IS24|A0A3B3IS24_HUMAN,tr|C9JIR6|C9JIR6_HUMAN" 4 1817.0047 4.28 35200 20257 3 1817.001965 606.6755 Protein phosphatase 1B OS=Homo sapiens OX=9606 GN=PPM1B PE=1 SV=1 6 3331.1 - 4.94E+06 - - - -1.5047 - 2.428 0.428 - 238.4 1 2 0 -0.0027 19 0 0 0 1.11E+08 2.60E+07 - - - 5.4904 1 221125_WJC_METTL3_EV_vs_WT_F03.20258.20258.3 7.80E-07 Dec-64 K.TTSEIFLSSTAEGADLR[166.11].T "sp|Q8IWZ3|ANKH1_HUMAN,tr|E9PDP5|E9PDP5_HUMAN,tr|D6RHC4|D6RHC4_HUMAN" 3 1806.8875 1.16 35201 20258 3 1806.887478 603.3031 Ankyrin repeat and KH domain-containing protein 1 OS=Homo sapiens OX=9606 GN=ANKHD1 PE=1 SV=1 4.14 3331.1 - 3.84E+06 - - - -0.0083 - 2.301 0.558 - 137.2 1 2 0 0 17 0 0 0 2.95E+07 2.55E+07 - - - 6.8664 1 221125_WJC_METTL3_EV_vs_WT_F03.20259.20259.2 1.40E-10 16/22 R.DVDFELIK[136.11]VEGK[136.11].V "sp|P48643|TCPE_HUMAN,tr|E9PCA1|E9PCA1_HUMAN,tr|B7ZAR1|B7ZAR1_HUMAN,tr|E7ENZ3|E7ENZ3_HUMAN" 4 1406.7628 0.7 35202 20259 2 1406.763971 704.3887 T-complex protein 1 subunit epsilon OS=Homo sapiens OX=9606 GN=CCT5 PE=1 SV=1 4.32 3331.2 - 3.67E+06 - - - 0.8345 - 3.013 0.672 - 769.1 1 2 1 0.0012 12 0 0 0 3.18E+07 4.53E+07 - - - 6.906 1 221125_WJC_METTL3_EV_vs_WT_F03.20260.20260.2 2.17E-10 17/28 K.GYGFVDFDSPSAAQK[136.11].A "sp|Q15434|RBMS2_HUMAN,tr|F8W1T6|F8W1T6_HUMAN" 2 1595.7347 1.53 35203 20260 2 1595.734225 798.8746 "RNA-binding motif, single-stranded-interacting protein 2 OS=Homo sapiens OX=9606 GN=RBMS2 PE=1 SV=1" 4.21 3331.3 - 2.96E+06 - - - -0.3215 - 3.412 0.684 - 1097.7 1 2 0 -0.0005 15 0 0 0 7.24E+07 4.72E+07 - - - 7.1102 0.9998 221125_WJC_METTL3_EV_vs_WT_F03.20261.20261.2 6.27E-06 20-Oct K.AQMTNILQQIK.T "sp|Q8ND24|RN214_HUMAN,tr|E9PN76|E9PN76_HUMAN" 2 1286.7017 1.47 35204 20261 2 1286.702834 644.3581 RING finger protein 214 OS=Homo sapiens OX=9606 GN=RNF214 PE=1 SV=2 8.8 3331.4 - 2.64E+06 - - - 0.9147 - 2.449 0.397 - 350.1 1 2 0 0.0012 11 0 0 0 1.62E+07 1.10E+07 - - - 4.3959 0.9999 221125_WJC_METTL3_EV_vs_WT_F03.20264.20264.3 1.48E-06 14/52 R.GVVDSEDIPLNLSR[166.11].E "sp|Q12931|TRAP1_HUMAN,sp|P08238|HS90B_HUMAN,sp|Q58FF7|H90B3_HUMAN,sp|P07900|HS90A_HUMAN,tr|I3L0K7|I3L0K7_HUMAN,tr|I3L239|I3L239_HUMAN" 6 1522.7867 0.91 35207 20264 3 1522.780598 508.6028 "Heat shock protein 75 kDa, mitochondrial OS=Homo sapiens OX=9606 GN=TRAP1 PE=1 SV=3" 4.03 3331.6 - 1.96E+06 - - - -3.9789 - 2.74 0.529 - 288.9 1 2 0 -0.0061 14 0 0 0 4.54E+07 5.00E+07 - - - 7.1148 0.9998 221125_WJC_METTL3_EV_vs_WT_F03.20265.20265.2 1.01E-06 13/20 K.DANLYISGLPR[166.11].T "sp|Q15717|ELAV1_HUMAN,tr|M0R055|M0R055_HUMAN,tr|M0QZR9|M0QZR9_HUMAN" 3 1227.6487 1.19 35208 20265 2 1227.648464 614.8316 ELAV-like protein 1 OS=Homo sapiens OX=9606 GN=ELAVL1 PE=1 SV=2 5.84 3331.8 - 1.66E+06 - - - -0.1979 - 2.617 0.36 - 716.5 1 2 0 -0.0002 11 0 0 0 1.76E+07 1.48E+07 - - - 4.3024 0.9998 221125_WJC_METTL3_EV_vs_WT_F03.20266.20266.3 1.78E-06 20/56 K.GHAVNLLDVPVPVAR.K sp|O00429|DNM1L_HUMAN 1 1555.8835 0.73 35209 20266 3 1555.87745 519.6351 Dynamin-1-like protein OS=Homo sapiens OX=9606 GN=DNM1L PE=1 SV=2 6.74 3331.9 - 1.20E+06 - - - -3.8634 - 2.688 0.492 - 572.6 1 2 0 -0.006 15 0 0 0 7.02E+06 9.57E+06 - - - 6.6038 0.9983 221125_WJC_METTL3_EV_vs_WT_F03.20267.20267.2 9.13E-07 15/36 R.ILSAENIPNLPPGGGLAGK[136.11].R "sp|O75688|PPM1B_HUMAN,tr|B8ZZF0|B8ZZF0_HUMAN,tr|A0A3B3IS24|A0A3B3IS24_HUMAN,tr|C9JIR6|C9JIR6_HUMAN" 4 1825.0189 3.7 35210 20267 2 1825.010232 913.5167 Protein phosphatase 1B OS=Homo sapiens OX=9606 GN=PPM1B PE=1 SV=1 6 3332 - 1.18E+06 - - - -4.749 - 2.19 0.554 - 364.6 1 2 0 -0.0087 19 0 0 0 9.76E+07 2.63E+07 - - - 5.0574 1 221125_WJC_METTL3_EV_vs_WT_F03.20270.20270.3 0.000595 19/64 K.MLQAPESVLAEHYQDLR[166.11].R "sp|O00746|NDKM_HUMAN,tr|Q4TT34|Q4TT34_HUMAN,tr|H0Y6J0|H0Y6J0_HUMAN,tr|F2Z2X0|F2Z2X0_HUMAN,tr|A2IDC9|A2IDC9_HUMAN" 5 2008.9916 2.09 35212 20270 3 2008.987116 670.6711 "Nucleoside diphosphate kinase, mitochondrial OS=Homo sapiens OX=9606 GN=NME4 PE=1 SV=1" 4.65 3332.4 - 1.09E+08 - - - -2.2225 - 3.775 0.547 - 391 1 2 0 -0.0045 17 0 0 0 2.27E+09 1.09E+09 - - - 7.9932 0.9999 221125_WJC_METTL3_EV_vs_WT_F03.20272.20272.3 8.39E-07 16/44 R.DVDFELIK[136.11]VEGK[136.11].V "sp|P48643|TCPE_HUMAN,tr|E9PCA1|E9PCA1_HUMAN,tr|B7ZAR1|B7ZAR1_HUMAN,tr|E7ENZ3|E7ENZ3_HUMAN" 4 1406.7628 0.64 35213 20272 3 1406.761671 469.9282 T-complex protein 1 subunit epsilon OS=Homo sapiens OX=9606 GN=CCT5 PE=1 SV=1 4.32 3332.6 - 3.20E+07 - - - -0.8004 - 2.543 0.596 - 262.9 1 2 1 -0.0011 12 0 0 0 1.61E+08 2.51E+08 - - - 7.7716 0.9996 221125_WJC_METTL3_EV_vs_WT_F03.20274.20274.2 0.0112 18-Nov K.DRPFFAGLVK.Y "sp|P15531|NDKA_HUMAN,tr|Q32Q12|Q32Q12_HUMAN,tr|J3KPD9|J3KPD9_HUMAN,tr|E5RHP0|E5RHP0_HUMAN,tr|E7ERL0|E7ERL0_HUMAN" 5 1148.6342 1.5 35215 20274 2 1148.633032 575.3244 Nucleoside diphosphate kinase A OS=Homo sapiens OX=9606 GN=NME1 PE=1 SV=1 8.75 3332.6 - 1.12E+07 - - - -1.0421 - 2.142 0.304 - 470.7 1 2 0 -0.0012 10 0 0 0 1.32E+08 8.81E+07 - - - 3.4122 0.9999 221125_WJC_METTL3_EV_vs_WT_F03.20275.20275.3 1.16E-06 Dec-64 K.TTSEIFLSSTAEGADLR.T "sp|Q8IWZ3|ANKH1_HUMAN,tr|E9PDP5|E9PDP5_HUMAN,tr|D6RHC4|D6RHC4_HUMAN" 3 1796.8792 1.15 35216 20275 3 1796.87508 599.967 Ankyrin repeat and KH domain-containing protein 1 OS=Homo sapiens OX=9606 GN=ANKHD1 PE=1 SV=1 4.14 3332.7 - 4.24E+06 - - - -2.3057 - 2.763 0.503 - 174.3 1 2 0 -0.0041 17 0 0 0 2.93E+07 2.55E+07 - - - 6.7143 0.9989 221125_WJC_METTL3_EV_vs_WT_F03.20278.20278.2 8.90E-06 22-Dec R.SVYENDVLEQLK.Q "sp|Q96P16|RPR1A_HUMAN,tr|A0A0C4DGQ6|A0A0C4DGQ6_HUMAN" 2 1435.7195 1.44 35219 20278 2 1435.713506 718.867 Regulation of nuclear pre-mRNA domain-containing protein 1A OS=Homo sapiens OX=9606 GN=RPRD1A PE=1 SV=1 4.14 3332.8 - 3.25E+06 - - - -4.1575 - 2.287 0.527 - 339.9 1 2 0 -0.006 12 0 0 0 3.71E+07 2.58E+07 - - - 5.1082 0.9999 221125_WJC_METTL3_EV_vs_WT_F03.20280.20280.3 0.000219 Dec-52 R.GVVDSEDIPLNLSR.E "sp|Q12931|TRAP1_HUMAN,sp|P08238|HS90B_HUMAN,sp|Q58FF7|H90B3_HUMAN,sp|P07900|HS90A_HUMAN,tr|I3L0K7|I3L0K7_HUMAN,tr|I3L239|I3L239_HUMAN" 6 1512.7784 0.9 35221 20280 3 1512.774986 505.2667 "Heat shock protein 75 kDa, mitochondrial OS=Homo sapiens OX=9606 GN=TRAP1 PE=1 SV=3" 4.03 3333 - 2.47E+06 - - - -2.2482 - 2.434 0.518 - 197.1 1 2 0 -0.0034 14 0 0 0 4.59E+07 5.13E+07 - - - 6.6782 0.9997 221125_WJC_METTL3_EV_vs_WT_F03.20282.20282.3 0.00049 16/72 R.ILSAENIPNLPPGGGLAGK[136.11].R "sp|O75688|PPM1B_HUMAN,tr|B8ZZF0|B8ZZF0_HUMAN,tr|A0A3B3IS24|A0A3B3IS24_HUMAN,tr|C9JIR6|C9JIR6_HUMAN" 4 1825.0189 4.32 35223 20282 3 1825.015163 609.3469 Protein phosphatase 1B OS=Homo sapiens OX=9606 GN=PPM1B PE=1 SV=1 6 3333.1 - 2.12E+06 - - - -2.0471 - 2.252 0.392 - 253 1 2 0 -0.0037 19 0 0 0 1.11E+08 2.57E+07 - - - 4.9039 0.9998 221125_WJC_METTL3_EV_vs_WT_F03.20286.20286.2 5.81E-06 13/24 R.TLQYLSQGNVVFK[136.11].D "sp|P82663|RT25_HUMAN,tr|E7EPW2|E7EPW2_HUMAN" 2 1503.8177 1.07 35227 20286 2 1503.8188 752.9161 "28S ribosomal protein S25, mitochondrial OS=Homo sapiens OX=9606 GN=MRPS25 PE=1 SV=1" 8.26 3333.6 - 1.20E+06 - - - 0.7454 - 2.382 0.421 - 453.6 1 2 0 0.0011 13 0 0 0 9.82E+06 9.22E+06 - - - 4.3777 0.9999 221125_WJC_METTL3_EV_vs_WT_F03.20291.20291.3 0.000103 14/60 R.QLYHLGVVEAYSGLTK.K sp|Q08211|DHX9_HUMAN 1 1776.941 1.3 35230 20291 3 1776.939018 593.321 ATP-dependent RNA helicase A OS=Homo sapiens OX=9606 GN=DHX9 PE=1 SV=4 6.75 3334.2 - 8.51E+06 - - - -1.1357 - 2.392 0.435 - 263.3 1 2 0 -0.002 16 0 0 0 1.00E+08 7.73E+07 - - - 5.627 0.9999 221125_WJC_METTL3_EV_vs_WT_F03.20292.20292.2 2.50E-08 26-Nov R.EDDVGTGAGLLEIK[136.11].K "sp|P49368|TCPG_HUMAN,tr|B4DUR8|B4DUR8_HUMAN" 2 1423.7286 0.38 35231 20292 2 1423.727347 712.8716 T-complex protein 1 subunit gamma OS=Homo sapiens OX=9606 GN=CCT3 PE=1 SV=4 3.92 3334.3 - 3.16E+06 - - - -0.8731 - 2.197 0.548 - 418.6 1 2 0 -0.0012 14 0 0 0 1.56E+07 4.13E+07 - - - 5.0633 1 221125_WJC_METTL3_EV_vs_WT_F03.20293.20293.3 3.09E-06 15/60 R.QLYHLGVVEAYSGLTK[136.11].K sp|Q08211|DHX9_HUMAN 1 1784.9552 1.28 35232 20293 3 1784.95671 595.9924 ATP-dependent RNA helicase A OS=Homo sapiens OX=9606 GN=DHX9 PE=1 SV=4 6.75 3334.3 - 7.79E+06 - - - 0.8258 - 2.681 0.469 - 353.5 1 2 0 0.0015 16 0 0 0 9.89E+07 7.73E+07 - - - 6.2989 1 221125_WJC_METTL3_EV_vs_WT_F03.20294.20294.2 1.08E-11 16/30 R.QLC[160.03]DNAGFDATNILNK[136.11].L sp|Q99832|TCPH_HUMAN 1 1800.8556 0.21 35233 20294 2 1800.851545 901.4351 T-complex protein 1 subunit eta OS=Homo sapiens OX=9606 GN=CCT7 PE=1 SV=2 4.21 3334.4 - 4.91E+06 - - - -2.2506 - 3.388 0.671 - 788.6 1 2 0 -0.0041 16 0 0 0 1.34E+07 6.33E+07 - - - 6.9957 0.9954 221125_WJC_METTL3_EV_vs_WT_F03.20300.20300.2 0.000449 13/24 K.LLQDFFNGK[136.11]ELNK[136.11].S "sp|P54652|HSP72_HUMAN,sp|P11142|HSP7C_HUMAN,sp|P17066|HSP76_HUMAN,tr|E9PNE6|E9PNE6_HUMAN,tr|A8K7Q2|A8K7Q2_HUMAN,tr|E9PKE3|E9PKE3_HUMAN,tr|E9PN89|E9PN89_HUMAN" 7 1580.8533 0.03 35239 20300 2 1580.849384 791.4339 Heat shock-related 70 kDa protein 2 OS=Homo sapiens OX=9606 GN=HSPA2 PE=1 SV=1 6.07 3335.1 - 1.07E+06 - - - -2.5043 - 2.115 0.506 - 498.4 1 2 1 -0.004 13 0 0 0 2.90E+05 8.33E+06 - - - 4.6995 1 221125_WJC_METTL3_EV_vs_WT_F03.20302.20302.2 9.66E-08 26-Dec K.QLDMQSSWVYETGR[166.11].L "sp|Q6PJT7|ZC3HE_HUMAN,tr|G3V256|G3V256_HUMAN,tr|G3V5I6|G3V5I6_HUMAN,tr|A0A3B3IT62|A0A3B3IT62_HUMAN,tr|H0YJA2|H0YJA2_HUMAN" 5 1708.7754 1.14 35241 20302 2 1708.77361 855.395 Zinc finger CCCH domain-containing protein 14 OS=Homo sapiens OX=9606 GN=ZC3H14 PE=1 SV=1 4.37 3335.4 - 774690 - - - -1.0709 - 2.742 0.602 - 539.5 1 2 0 -0.0018 14 0 0 0 5.13E+06 4.50E+06 - - - 6.018 1 221125_WJC_METTL3_EV_vs_WT_F03.20307.20307.2 5.96E-10 15/22 R.SVYENDVLEQLK[136.11].Q "sp|Q96P16|RPR1A_HUMAN,tr|A0A0C4DGQ6|A0A0C4DGQ6_HUMAN" 2 1443.7337 1.49 35244 20307 2 1443.729539 722.8741 Regulation of nuclear pre-mRNA domain-containing protein 1A OS=Homo sapiens OX=9606 GN=RPRD1A PE=1 SV=1 4.14 3336 - 2.05E+06 - - - -2.8648 - 2.55 0.609 - 570.8 1 2 0 -0.0041 12 0 0 0 3.84E+07 2.58E+07 - - - 6.0008 1 221125_WJC_METTL3_EV_vs_WT_F03.20308.20308.3 5.44E-09 20/68 K.VTEELAAATAQVSHLQLK.M sp|Q5T1M5|FKB15_HUMAN 1 1908.0316 4.42 35245 20308 3 1908.032157 637.0178 FK506-binding protein 15 OS=Homo sapiens OX=9606 GN=FKBP15 PE=1 SV=2 5.4 3336.1 - 1.56E+06 - - - 0.2699 - 4.045 0.513 - 533.1 1 2 0 0.0005 18 0 0 0 1.25E+07 2.83E+06 - - - 7.7392 1 221125_WJC_METTL3_EV_vs_WT_F03.20310.20310.2 1.93E-09 17/26 T.VDNANVLLQIDNAR.L sp|P02533|K1C14_HUMAN 1 1553.8162 999 35247 20310 2 1553.812102 777.9154 "Keratin, type I cytoskeletal 14 OS=Homo sapiens OX=9606 GN=KRT14 PE=1 SV=4" 4.21 3336.3 - 1.50E+06 - - - -2.6174 - 3.201 0.618 - 1107.2 1 1 0 -0.0041 14 0 0 0 3.16E+07 0.00E+00 - - - 6.5239 0.9995 221125_WJC_METTL3_EV_vs_WT_F03.20311.20311.2 0.000271 15/24 R.NEDLEEIASTDLK[136.11].Y sp|P78318|IGBP1_HUMAN 1 1483.7133 0.98 35248 20311 2 1483.709241 742.8639 Immunoglobulin-binding protein 1 OS=Homo sapiens OX=9606 GN=IGBP1 PE=1 SV=1 3.83 3336.4 - 1.46E+06 - - - -2.7586 - 2.87 0.412 - 933.6 1 2 0 -0.0041 13 0 0 0 1.05E+07 1.08E+07 - - - 4.7887 0.9998 221125_WJC_METTL3_EV_vs_WT_F03.20312.20312.2 0.0419 13/24 R.NEDLEEIASTDLK.Y sp|P78318|IGBP1_HUMAN 1 1475.6991 0.98 35249 20312 2 1475.696575 738.8568 Immunoglobulin-binding protein 1 OS=Homo sapiens OX=9606 GN=IGBP1 PE=1 SV=1 3.83 3336.6 - 1.38E+06 - - - -1.7341 - 2.481 0.443 - 471.1 1 2 0 -0.0026 13 0 0 0 1.05E+07 1.08E+07 - - - 4.6443 0.9999 221125_WJC_METTL3_EV_vs_WT_F03.20313.20313.2 9.77E-06 13/24 K.DQGTYEDYVEGLR.V "sp|P60660|MYL6_HUMAN,tr|F8W1R7|F8W1R7_HUMAN,tr|G3V1V0|G3V1V0_HUMAN,tr|B7Z6Z4|B7Z6Z4_HUMAN,tr|F8VZU9|F8VZU9_HUMAN,tr|G8JLA2|G8JLA2_HUMAN,tr|H0YI43|H0YI43_HUMAN,tr|F8W180|F8W180_HUMAN,tr|G3V1Y7|G3V1Y7_HUMAN,tr|J3KND3|J3KND3_HUMAN,tr|F8VPF3|F8VPF3_HUMAN" 11 1543.6791 1.24 35250 20313 2 1543.67701 772.8468 Myosin light polypeptide 6 OS=Homo sapiens OX=9606 GN=MYL6 PE=1 SV=2 3.92 3336.7 - 1.36E+06 - - - -1.3325 - 2.665 0.541 - 818.4 1 2 0 -0.0021 13 0 0 0 2.29E+07 1.85E+07 - - - 5.5519 1 221125_WJC_METTL3_EV_vs_WT_F03.20314.20314.3 6.53E-10 14/60 R.QLC[160.03]DNAGFDATNILNK[136.11].L sp|Q99832|TCPH_HUMAN 1 1800.8556 0.55 35251 20314 3 1800.853701 601.2925 T-complex protein 1 subunit eta OS=Homo sapiens OX=9606 GN=CCT7 PE=1 SV=2 4.21 3336.7 - 3.80E+06 - - - -1.0534 - 2.691 0.641 - 280 1 2 0 -0.0019 16 0 0 0 1.66E+07 3.00E+07 - - - 8.226 0.9999 221125_WJC_METTL3_EV_vs_WT_F03.20322.20322.2 8.89E-06 Dec-32 K.LSPPYSSPQEFAQDVGR[166.11].M "sp|Q13263|TIF1B_HUMAN,tr|M0R0K9|M0R0K9_HUMAN" 2 1886.9038 0.8 35258 20322 2 1886.90591 944.4592 Transcription intermediary factor 1-beta OS=Homo sapiens OX=9606 GN=TRIM28 PE=1 SV=5 4.37 3337.7 - 549590 - - - 1.1119 - 2.103 0.583 - 187.1 1 2 0 0.0021 17 0 0 0 1.02E+07 1.26E+07 - - - 5.174 1 221125_WJC_METTL3_EV_vs_WT_F03.20325.20325.3 5.95E-09 17/56 K.VFEPNEEALGVVLHK.D "sp|O43615|TIM44_HUMAN,tr|M0QXU7|M0QXU7_HUMAN" 2 1679.8883 1.17 35260 20325 3 1679.888898 560.97 Mitochondrial import inner membrane translocase subunit TIM44 OS=Homo sapiens OX=9606 GN=TIMM44 PE=1 SV=2 4.75 3338 - 3.75E+06 - - - 0.3726 - 3.131 0.621 - 316.8 1 2 0 0.0006 15 0 0 0 2.47E+08 2.11E+08 - - - 8.4416 0.9999 221125_WJC_METTL3_EV_vs_WT_F03.20327.20327.2 1.79E-08 26-Oct R.SSFYVNGLTLGGQK[136.11].C "sp|P07737|PROF1_HUMAN,tr|K7EJ44|K7EJ44_HUMAN,tr|I3L3D5|I3L3D5_HUMAN" 3 1477.7656 3.53 35262 20327 2 1477.764648 739.8901 Profilin-1 OS=Homo sapiens OX=9606 GN=PFN1 PE=1 SV=2 8.31 3338.1 - 2.67E+06 - - - -0.674 - 2.253 0.584 - 227.4 1 2 0 -0.001 14 0 0 0 9.11E+07 2.58E+07 - - - 5.3924 1 221125_WJC_METTL3_EV_vs_WT_F03.20328.20328.2 1.66E-06 15/28 K.SISVIDSPGILSGEK.Q sp|Q9H223|EHD4_HUMAN 1 1500.8035 1.76 35263 20328 2 1500.804828 751.409 EH domain-containing protein 4 OS=Homo sapiens OX=9606 GN=EHD4 PE=1 SV=1 4.37 3338.2 - 2.09E+06 - - - 0.8589 - 2.601 0.588 - 690.1 1 2 0 0.0013 15 0 0 0 4.04E+07 2.29E+07 - - - 5.7337 0.9999 221125_WJC_METTL3_EV_vs_WT_F03.20330.20330.2 0.00295 14/22 K.SIDLPIQSSLC[160.03]R[166.11].Q "sp|O95757|HS74L_HUMAN,tr|E9PDE8|E9PDE8_HUMAN" 2 1397.7212 0.04 35265 20330 2 1397.721094 699.8679 Heat shock 70 kDa protein 4L OS=Homo sapiens OX=9606 GN=HSPA4L PE=1 SV=3 5.55 3338.5 - 1.95E+06 - - - -0.0901 - 2.4 0.446 - 690.2 1 2 0 -0.0001 12 0 0 0 6.16E+05 1.44E+07 - - - 4.6386 0.9997 221125_WJC_METTL3_EV_vs_WT_F03.20334.20334.3 5.25E-06 15/48 R.EKVGEVTYVELFK.D "sp|Q9P2K5|MYEF2_HUMAN,tr|A0A0A0MR39|A0A0A0MR39_HUMAN,tr|A0A087WUT0|A0A087WUT0_HUMAN,tr|A0A0A0MQW0|A0A0A0MQW0_HUMAN" 4 1539.8185 0.98 35269 20334 3 1539.816971 514.2801 Myelin expression factor 2 OS=Homo sapiens OX=9606 GN=MYEF2 PE=1 SV=3 4.79 3338.8 - 1.65E+06 - - - -0.9676 - 2.5 0.424 - 317.7 1 2 1 -0.0015 13 0 0 0 3.09E+07 3.16E+07 - - - 5.7511 1 221125_WJC_METTL3_EV_vs_WT_F03.20335.20335.3 5.58E-08 16/48 R.FHQLDIDDLQSIR[166.11].A "sp|P16152|CBR1_HUMAN,sp|O75828|CBR3_HUMAN,tr|E9PQ63|E9PQ63_HUMAN,tr|A8MTM1|A8MTM1_HUMAN" 4 1608.8135 1.2 35270 20335 3 1608.813725 537.2785 Carbonyl reductase [NADPH] 1 OS=Homo sapiens OX=9606 GN=CBR1 PE=1 SV=3 4.41 3338.9 - 1.63E+06 - - - 0.115 - 3.195 0.553 - 576.1 1 2 0 0.0002 13 0 0 0 5.37E+07 4.48E+07 - - - 7.8548 1 221125_WJC_METTL3_EV_vs_WT_F03.20336.20336.3 7.04E-06 14/48 R.FHQLDIDDLQSIR.A "sp|P16152|CBR1_HUMAN,sp|O75828|CBR3_HUMAN,tr|E9PQ63|E9PQ63_HUMAN,tr|A8MTM1|A8MTM1_HUMAN" 4 1598.8053 1.2 35271 20336 3 1598.803907 533.9424 Carbonyl reductase [NADPH] 1 OS=Homo sapiens OX=9606 GN=CBR1 PE=1 SV=3 4.41 3338.9 - 1.62E+06 - - - -0.8525 - 2.827 0.53 - 449 1 2 0 -0.0014 13 0 0 0 5.37E+07 4.48E+07 - - - 7.2662 0.9996 221125_WJC_METTL3_EV_vs_WT_F03.20337.20337.3 1.24E-06 17/56 K.DLDADREVTFLEASR.F "sp|P20338|RAB4A_HUMAN,tr|A0A087WYT5|A0A087WYT5_HUMAN" 2 1735.8377 1.11 35272 20337 3 1735.832557 579.6198 Ras-related protein Rab-4A OS=Homo sapiens OX=9606 GN=RAB4A PE=1 SV=3 4.11 3339 - 1.56E+06 - - - -2.9588 - 2.843 0.483 - 338.6 1 2 1 -0.0051 15 0 0 0 1.06E+07 9.57E+06 - - - 6.65 0.9998 221125_WJC_METTL3_EV_vs_WT_F03.20338.20338.2 1.06E-07 17/26 K.SAWLSGYENPVVSR[166.11].L sp|P13674|P4HA1_HUMAN 1 1573.7764 1.64 35273 20338 2 1573.77992 787.8955 Prolyl 4-hydroxylase subunit alpha-1 OS=Homo sapiens OX=9606 GN=P4HA1 PE=1 SV=2 5.72 3339.1 - 1.43E+06 - - - 2.2195 - 2.927 0.514 - 719.2 1 2 0 0.0035 14 0 0 0 5.92E+07 3.61E+07 - - - 5.5314 0.9999 221125_WJC_METTL3_EV_vs_WT_F03.20340.20340.3 0.00632 Dec-44 R.VQDGKPVILLFR.T "sp|Q9NRG9|AAAS_HUMAN,tr|H3BU82|H3BU82_HUMAN,tr|F8VZ44|F8VZ44_HUMAN,tr|F8VUB6|F8VUB6_HUMAN" 4 1383.8238 1.8 35275 20340 3 1383.822858 462.2819 Aladin OS=Homo sapiens OX=9606 GN=AAAS PE=1 SV=1 8.72 3339.3 - 1.24E+06 - - - -0.6959 - 2.19 0.372 - 151.2 1 2 0 -0.001 12 0 0 0 1.98E+07 1.10E+07 - - - 4.86 1 221125_WJC_METTL3_EV_vs_WT_F03.20345.20345.3 6.79E-08 19/64 K.MLQAPESVLAEHYQDLR.R "sp|O00746|NDKM_HUMAN,tr|Q4TT34|Q4TT34_HUMAN,tr|H0Y6J0|H0Y6J0_HUMAN,tr|F2Z2X0|F2Z2X0_HUMAN,tr|A2IDC9|A2IDC9_HUMAN" 5 1998.9833 2.09 35279 20345 3 1998.983345 667.335 "Nucleoside diphosphate kinase, mitochondrial OS=Homo sapiens OX=9606 GN=NME4 PE=1 SV=1" 4.65 3339.9 - 1.84E+07 - - - 0.017 - 3.736 0.615 - 467.7 1 2 0 0 17 0 0 0 2.27E+09 1.09E+09 - - - 8.7263 0.9997 221125_WJC_METTL3_EV_vs_WT_F03.20346.20346.2 2.45E-06 24-Nov R.QGNMTAALQAALK.N "sp|O15511|ARPC5_HUMAN,tr|B1ALC0|B1ALC0_HUMAN" 2 1315.6918 1.81 35280 20346 2 1315.693789 658.8532 Actin-related protein 2\3 complex subunit 5 OS=Homo sapiens OX=9606 GN=ARPC5 PE=1 SV=3 8.75 3340 - 526477 - - - 1.4966 - 1.953 0.511 - 359.7 1 2 0 0.002 13 0 0 0 4.74E+06 2.62E+06 - - - 4.5326 1 221125_WJC_METTL3_EV_vs_WT_F03.20347.20347.3 5.69E-08 19/60 R.QVVQGLLSETYLEAHR.L sp|P33993|MCM7_HUMAN 1 1841.9636 0.79 35281 20347 3 1841.962182 614.9951 DNA replication licensing factor MCM7 OS=Homo sapiens OX=9606 GN=MCM7 PE=1 SV=4 5.4 3340 - 4.80E+06 - - - -0.7492 - 3.592 0.605 - 689.8 1 2 0 -0.0014 16 0 0 0 2.57E+07 3.26E+07 - - - 8.5658 0.9935 221125_WJC_METTL3_EV_vs_WT_F03.20349.20349.2 4.11E-07 15/24 L.TAEILELAGNAAR.D "sp|P16104|H2AX_HUMAN,sp|Q9BTM1|H2AJ_HUMAN,sp|Q93077|H2A1C_HUMAN,sp|Q99878|H2A1J_HUMAN,sp|Q16777|H2A2C_HUMAN,sp|Q8IUE6|H2A2B_HUMAN,sp|O75367|H2AY_HUMAN,sp|P04908|H2A1B_HUMAN,sp|P20671|H2A1D_HUMAN,sp|P0C0S8|H2A1_HUMAN,sp|Q6FI13|H2A2A_HUMAN,sp|Q96KK5|H2A1H_HUMAN,sp|Q7L7L0|H2A3_HUMAN,tr|A0A0U1RR32|A0A0U1RR32_HUMAN,tr|A0A0U1RRH7|A0A0U1RRH7_HUMAN,tr|D6RCF2|D6RCF2_HUMAN,tr|A0A3B3IS11|A0A3B3IS11_HUMAN,tr|H0YFX9|H0YFX9_HUMAN" 18 1327.7096 1.38 35283 20349 2 1327.707994 664.8621 Histone H2AX OS=Homo sapiens OX=9606 GN=H2AX PE=1 SV=2 4.53 3340.1 - 3.36E+06 - - - -1.1938 - 2.921 0.525 - 851.7 1 1 0 -0.0016 13 0 0 0 5.23E+07 3.79E+07 - - - 5.6693 0.9999 221125_WJC_METTL3_EV_vs_WT_F03.20350.20350.3 0.00397 Dec-56 R.SDGALLLGASSLSGR.C sp|Q9BQA1|MEP50_HUMAN 1 1402.7416 4.71 35284 20350 3 1402.740822 468.5878 Methylosome protein 50 OS=Homo sapiens OX=9606 GN=WDR77 PE=1 SV=1 5.55 3340.2 - 2.38E+06 - - - -0.5596 - 2.477 0.429 - 203.4 1 2 0 -0.0008 15 0 0 0 2.79E+07 5.93E+06 - - - 5.6895 0.9974 221125_WJC_METTL3_EV_vs_WT_F03.20351.20351.3 2.03E-05 Dec-44 K.HWPFMVVNDAGR[166.11].P "sp|P11142|HSP7C_HUMAN,tr|E9PQQ4|E9PQQ4_HUMAN,tr|E9PNE6|E9PNE6_HUMAN,tr|E9PKE3|E9PKE3_HUMAN,tr|E9PN89|E9PN89_HUMAN,tr|E9PLF4|E9PLF4_HUMAN,tr|E9PK54|E9PK54_HUMAN,tr|E9PN25|E9PN25_HUMAN,tr|E9PPY6|E9PPY6_HUMAN,tr|E9PQK7|E9PQK7_HUMAN" 10 1437.6851 0.05 35285 20351 3 1437.684613 480.2356 Heat shock cognate 71 kDa protein OS=Homo sapiens OX=9606 GN=HSPA8 PE=1 SV=1 6.74 3340.3 - 2.73E+06 - - - -0.345 - 2.511 0.508 - 332.8 1 1 0 -0.0005 12 0 0 0 5.08E+05 1.10E+07 - - - 6.7556 1 221125_WJC_METTL3_EV_vs_WT_F03.20352.20352.2 1.03E-11 17/28 K.AFNSSSFNSNTFLTR.L sp|P46060|RAGP1_HUMAN 1 1691.7903 0.99 35286 20352 2 1691.792232 846.9025 Ran GTPase-activating protein 1 OS=Homo sapiens OX=9606 GN=RANGAP1 PE=1 SV=1 9.79 3340.4 - 1.60E+06 - - - 1.113 - 3.229 0.64 - 870 1 2 0 0.0019 15 0 0 0 1.32E+07 1.33E+07 - - - 6.6493 1 221125_WJC_METTL3_EV_vs_WT_F03.20355.20355.3 0.000138 17/56 R.SDGALLLGASSLSGR[166.11].C sp|Q9BQA1|MEP50_HUMAN 1 1412.7499 4.71 35289 20355 3 1412.748961 471.9239 Methylosome protein 50 OS=Homo sapiens OX=9606 GN=WDR77 PE=1 SV=1 5.55 3340.7 - 1.29E+06 - - - -0.6484 - 3.021 0.461 - 669.2 1 2 0 -0.0009 15 0 0 0 2.79E+07 5.93E+06 - - - 6.5643 0.9977 221125_WJC_METTL3_EV_vs_WT_F03.20358.20358.3 1.94E-10 18/48 L.TAEILELAGNAAR.D "sp|P16104|H2AX_HUMAN,sp|Q9BTM1|H2AJ_HUMAN,sp|Q93077|H2A1C_HUMAN,sp|Q99878|H2A1J_HUMAN,sp|Q16777|H2A2C_HUMAN,sp|Q8IUE6|H2A2B_HUMAN,sp|O75367|H2AY_HUMAN,sp|P04908|H2A1B_HUMAN,sp|P20671|H2A1D_HUMAN,sp|P0C0S8|H2A1_HUMAN,sp|Q6FI13|H2A2A_HUMAN,sp|Q96KK5|H2A1H_HUMAN,sp|Q7L7L0|H2A3_HUMAN,tr|A0A0U1RR32|A0A0U1RR32_HUMAN,tr|A0A0U1RRH7|A0A0U1RRH7_HUMAN,tr|D6RCF2|D6RCF2_HUMAN,tr|A0A3B3IS11|A0A3B3IS11_HUMAN,tr|H0YFX9|H0YFX9_HUMAN" 18 1327.7096 1.35 35292 20358 3 1327.708943 443.5771 Histone H2AX OS=Homo sapiens OX=9606 GN=H2AX PE=1 SV=2 4.53 3341 - 1.09E+06 - - - -0.479 - 3.356 0.455 - 557.5 1 1 0 -0.0006 13 0 0 0 1.78E+07 1.32E+07 - - - 6.8953 0.996 221125_WJC_METTL3_EV_vs_WT_F03.20359.20359.3 2.99E-07 15/48 L.TAEILELAGNAAR[166.11].D "sp|P16104|H2AX_HUMAN,sp|Q9BTM1|H2AJ_HUMAN,sp|Q93077|H2A1C_HUMAN,sp|Q99878|H2A1J_HUMAN,sp|Q16777|H2A2C_HUMAN,sp|Q8IUE6|H2A2B_HUMAN,sp|O75367|H2AY_HUMAN,sp|P04908|H2A1B_HUMAN,sp|P20671|H2A1D_HUMAN,sp|P0C0S8|H2A1_HUMAN,sp|Q6FI13|H2A2A_HUMAN,sp|Q96KK5|H2A1H_HUMAN,sp|Q7L7L0|H2A3_HUMAN,tr|A0A0U1RR32|A0A0U1RR32_HUMAN,tr|A0A0U1RRH7|A0A0U1RRH7_HUMAN,tr|D6RCF2|D6RCF2_HUMAN,tr|A0A3B3IS11|A0A3B3IS11_HUMAN,tr|H0YFX9|H0YFX9_HUMAN" 18 1337.7178 1.37 35293 20359 3 1337.71673 446.9132 Histone H2AX OS=Homo sapiens OX=9606 GN=H2AX PE=1 SV=2 4.53 3341.1 - 1.05E+06 - - - -0.8365 - 3.195 0.406 - 416.2 1 1 0 -0.0011 13 0 0 0 1.86E+07 1.36E+07 - - - 6.2156 1 221125_WJC_METTL3_EV_vs_WT_F03.20362.20362.2 7.61E-09 17/30 K.TTLQVDTLNAELAAER[166.11].S sp|P35580|MYH10_HUMAN 1 1753.9086 1.1 35296 20362 2 1753.910409 877.9616 Myosin-10 OS=Homo sapiens OX=9606 GN=MYH10 PE=1 SV=3 4.14 3341.5 - 859601 - - - 1.0525 - 3.774 0.605 - 1079.4 1 2 0 0.0018 16 0 0 0 5.37E+06 4.87E+06 - - - 6.7742 1 221125_WJC_METTL3_EV_vs_WT_F03.20364.20364.2 3.07E-10 17/30 K.TTLQVDTLNAELAAER.S sp|P35580|MYH10_HUMAN 1 1743.9003 1.1 35298 20364 2 1743.904445 872.9574 Myosin-10 OS=Homo sapiens OX=9606 GN=MYH10 PE=1 SV=3 4.14 3341.7 - 777301 - - - 2.3809 - 3.601 0.57 - 840.8 1 2 0 0.0042 16 0 0 0 5.37E+06 4.87E+06 - - - 6.3996 1 221125_WJC_METTL3_EV_vs_WT_F03.20366.20366.2 7.84E-09 13/30 K.ELVNDDEDIDWVQTEK[136.11].H sp|P41743|KPCI_HUMAN 1 1954.8887 1.42 35299 20366 2 1954.882998 978.4516 Protein kinase C iota type OS=Homo sapiens OX=9606 GN=PRKCI PE=1 SV=2 3.62 3342.1 - 345938 - - - -2.9332 - 2.931 0.624 - 495.7 1 2 0 -0.0057 16 0 0 0 4.47E+06 3.14E+06 - - - 6.2918 1 221125_WJC_METTL3_EV_vs_WT_F03.20368.20368.2 2.63E-05 14/26 R.EAGNINQSLLTLGR.V "sp|P52732|KIF11_HUMAN,tr|A0A7I2YQY4|A0A7I2YQY4_HUMAN,tr|A0A7I2V3A9|A0A7I2V3A9_HUMAN,tr|A0A7I2V3V3|A0A7I2V3V3_HUMAN" 4 1484.7947 4.19 35301 20368 2 1484.792547 743.4046 Kinesin-like protein KIF11 OS=Homo sapiens OX=9606 GN=KIF11 PE=1 SV=2 6.1 3342.2 - 2.38E+07 - - - -1.4541 - 2.952 0.595 - 595.3 1 2 0 -0.0022 14 0 0 0 1.13E+09 2.70E+08 - - - 6.1514 0.9934 221125_WJC_METTL3_EV_vs_WT_F03.20369.20369.3 0.00147 Dec-48 L.DGIHLLDPDVVAR[166.11].F sp|Q86U44|MTA70_HUMAN 1 1428.76 0.02 35302 20369 3 1428.758048 477.2606 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 4.41 3342.3 - 1.29E+07 - - - -1.3998 - 2.648 0.421 - 290.6 1 1 0 -0.002 13 0 0 0 2.45E+07 1.22E+09 - - - 5.8734 1 221125_WJC_METTL3_EV_vs_WT_F03.20371.20371.3 1.52E-10 20/72 K.VLDSGAPIKIPVGPETLGR.L "sp|P06576|ATPB_HUMAN,tr|F8W079|F8W079_HUMAN,tr|H0YH81|H0YH81_HUMAN" 3 1918.0888 1.85 35304 20371 3 1918.089491 640.3702 "ATP synthase subunit beta, mitochondrial OS=Homo sapiens OX=9606 GN=ATP5F1B PE=1 SV=3" 6.04 3342.4 - 6.84E+06 - - - 0.3795 - 3.154 0.608 - 318.3 1 2 1 0.0007 19 0 0 0 1.86E+08 1.01E+08 - - - 8.1405 0.9999 221125_WJC_METTL3_EV_vs_WT_F03.20372.20372.3 1.32E-06 19/72 K.VLDSGAPIK[136.11]IPVGPETLGR[166.11].L "sp|P06576|ATPB_HUMAN,tr|F8W079|F8W079_HUMAN,tr|H0YH81|H0YH81_HUMAN" 3 1936.1112 1.85 35305 20372 3 1936.110041 646.3777 "ATP synthase subunit beta, mitochondrial OS=Homo sapiens OX=9606 GN=ATP5F1B PE=1 SV=3" 6.04 3342.4 - 3.64E+06 - - - -0.6157 - 2.908 0.592 - 259.2 1 2 1 -0.0012 19 0 0 0 1.86E+08 1.01E+08 - - - 7.7624 0.9917 221125_WJC_METTL3_EV_vs_WT_F03.20377.20377.2 4.88E-06 22-Oct R.DFTSLENTVEER.L sp|Q07065|CKAP4_HUMAN 1 1438.6576 0.64 35310 20377 2 1438.648271 720.3361 Cytoskeleton-associated protein 4 OS=Homo sapiens OX=9606 GN=CKAP4 PE=1 SV=2 4 3343 - 850799 - - - -6.4866 - 2.017 0.484 - 306.5 1 2 0 -0.0093 12 0 0 0 4.01E+06 6.22E+06 - - - 4.459 1 221125_WJC_METTL3_EV_vs_WT_F03.20379.20379.2 1.95E-09 13/30 R.ASNLENSTYDLYTIPK[136.11].D "sp|P53621|COPA_HUMAN,tr|A0A3B3ISC6|A0A3B3ISC6_HUMAN,tr|A0A3B3ITV3|A0A3B3ITV3_HUMAN,tr|A0A3B3IS84|A0A3B3IS84_HUMAN,tr|A0A3B3IU89|A0A3B3IU89_HUMAN,tr|A0A3B3ISK1|A0A3B3ISK1_HUMAN,tr|A0A3B3IT15|A0A3B3IT15_HUMAN" 7 1835.9033 0.17 35312 20379 2 1836.904758 918.9589 Coatomer subunit alpha OS=Homo sapiens OX=9606 GN=COPA PE=1 SV=2 4.37 3343.3 - 816104 - - - 545.507 - 2.837 0.628 - 309.2 1 2 0 1.0015 16 0 0 0 4.27E+06 2.57E+07 - - - 5.9286 0.9978 221125_WJC_METTL3_EV_vs_WT_F03.20380.20380.2 0.000169 18-Jul K.EDWNEIDPIK.K sp|Q10471|GALT2_HUMAN 1 1257.5877 1.96 35313 20380 2 1257.582753 629.8011 Polypeptide N-acetylgalactosaminyltransferase 2 OS=Homo sapiens OX=9606 GN=GALNT2 PE=1 SV=1 3.92 3343.4 - 802385 - - - -3.96 - 1.73 0.441 - 150.2 1 2 0 -0.005 10 0 0 0 1.58E+07 8.07E+06 - - - 3.8266 0.9997 221125_WJC_METTL3_EV_vs_WT_F03.20381.20381.3 0.000286 13/36 R.YIHLENLLAR[166.11].S sp|Q2TAY7|SMU1_HUMAN 1 1250.7011 0.98 35314 20381 3 1250.700327 417.9076 WD40 repeat-containing protein SMU1 OS=Homo sapiens OX=9606 GN=SMU1 PE=1 SV=2 6.75 3343.5 - 746669 - - - -0.5997 - 2.59 0.264 - 335.5 1 2 0 -0.0007 10 0 0 0 1.57E+07 1.61E+07 - - - 4.2624 0.9988 221125_WJC_METTL3_EV_vs_WT_F03.20382.20382.3 0.0382 13/60 K.TTLQVDTLNAELAAER[166.11].S sp|P35580|MYH10_HUMAN 1 1753.9086 0.76 35315 20382 3 1753.908669 585.6435 Myosin-10 OS=Homo sapiens OX=9606 GN=MYH10 PE=1 SV=3 4.14 3343.6 - 741780 - - - 0.0604 - 1.87 0.272 - 122.6 1 2 0 0.0001 16 0 0 0 3.19E+06 4.19E+06 - - - 3.1786 0.9998 221125_WJC_METTL3_EV_vs_WT_F03.20383.20383.3 9.18E-05 15/36 R.YIHLENLLAR.S sp|Q2TAY7|SMU1_HUMAN 1 1240.6928 0.98 35316 20383 3 1240.690831 414.5715 WD40 repeat-containing protein SMU1 OS=Homo sapiens OX=9606 GN=SMU1 PE=1 SV=2 6.75 3343.8 - 598542 - - - -1.5927 - 2.931 0.276 - 255.6 1 2 0 -0.002 10 0 0 0 1.57E+07 1.61E+07 - - - 4.7571 0.9496 221125_WJC_METTL3_EV_vs_WT_F03.20384.20384.2 0.00249 30-Nov K.VDVEVPDVSLEGPEGK.L sp|Q09666|AHNK_HUMAN 1 1667.8254 1.06 35317 20384 2 1667.811093 834.92 Neuroblast differentiation-associated protein AHNAK OS=Homo sapiens OX=9606 GN=AHNAK PE=1 SV=2 3.83 3343.9 - 544562 - - - -8.5764 - 2.01 0.362 - 282 1 2 0 -0.0143 16 0 0 0 1.45E+06 1.37E+06 - - - 3.4266 0.9977 221125_WJC_METTL3_EV_vs_WT_F03.20385.20385.3 0.0708 Aug-40 R.ALLHYLDFGQK[136.11].Q sp|Q14147|DHX34_HUMAN 1 1311.7067 -1 35318 20385 3 1311.704419 438.2428 Probable ATP-dependent RNA helicase DHX34 OS=Homo sapiens OX=9606 GN=DHX34 PE=1 SV=2 6.79 3344 - 267106 - - - -1.7176 - 1.455 0.305 - 48.7 1 2 0 -0.0023 11 0 0 0 0.00E+00 0.00E+00 - - - 3.0052 1 221125_WJC_METTL3_EV_vs_WT_F03.20387.20387.2 0.00027 14/28 R.SDGALLLGASSLSGR.C sp|Q9BQA1|MEP50_HUMAN 1 1402.7416 2.82 35319 20387 2 1402.741545 702.3781 Methylosome protein 50 OS=Homo sapiens OX=9606 GN=WDR77 PE=1 SV=1 5.55 3344.2 - 2.65E+07 - - - -0.0442 - 3.007 0.573 - 556.8 1 2 0 -0.0001 15 0 0 0 2.17E+08 7.71E+07 - - - 5.9799 0.9994 221125_WJC_METTL3_EV_vs_WT_F03.20388.20388.2 0.00068 14/28 K.AFNSSSFNSNTFLTR[166.11].L sp|P46060|RAGP1_HUMAN 1 1701.7986 1.02 35320 20388 2 1701.796136 851.9066 Ran GTPase-activating protein 1 OS=Homo sapiens OX=9606 GN=RANGAP1 PE=1 SV=1 9.79 3344.3 - 2.43E+06 - - - -1.459 - 1.865 0.36 - 328.7 1 2 0 -0.0025 15 0 0 0 1.32E+07 1.30E+07 - - - 3.2315 1 221125_WJC_METTL3_EV_vs_WT_F03.20390.20390.2 5.03E-09 15/26 K.YQGTILSIDDNLQR.T sp|Q02413|DSG1_HUMAN 1 1634.8264 299.56 35322 20390 2 1634.825915 818.4205 Desmoglein-1 OS=Homo sapiens OX=9606 GN=DSG1 PE=1 SV=2 4.21 3344.4 - 1.13E+07 - - - -0.2967 - 2.786 0.67 - 790.7 1 2 0 -0.0005 14 0 0 0 1.13E+08 3.78E+05 - - - 6.5607 0.9999 221125_WJC_METTL3_EV_vs_WT_F03.20391.20391.3 3.16E-05 18/88 K.TELAEPIAIR[166.11]PTSETVMYPAYAK[136.11].W sp|P07814|SYEP_HUMAN 1 2568.3264 0.89 35323 20391 3 2568.325066 857.1161 Bifunctional glutamate\proline--tRNA ligase OS=Homo sapiens OX=9606 GN=EPRS1 PE=1 SV=5 4.78 3344.5 - 3.83E+06 - - - -0.5377 - 2.657 0.384 - 297.6 1 2 0 -0.0014 23 0 0 0 2.69E+07 3.03E+07 - - - 5.1133 0.9999 221125_WJC_METTL3_EV_vs_WT_F03.20392.20392.3 0.0132 14/48 R.LVNLQHLDLLNNK.L sp|Q96AG4|LRC59_HUMAN 1 1532.8675 1.34 35324 20392 3 1532.866823 511.9631 Leucine-rich repeat-containing protein 59 OS=Homo sapiens OX=9606 GN=LRRC59 PE=1 SV=1 6.74 3344.5 - 2.54E+06 - - - -0.4267 - 2.886 0.397 - 204.2 1 2 0 -0.0007 13 0 0 0 1.90E+08 1.41E+08 - - - 5.8396 0.9044 221125_WJC_METTL3_EV_vs_WT_F03.20394.20394.2 1.43E-06 17/22 E.PNEEALGVVLHK[136.11].D "sp|O43615|TIM44_HUMAN,tr|M0QXU7|M0QXU7_HUMAN" 2 1312.7231 0.86 35326 20394 2 1312.725047 657.3688 Mitochondrial import inner membrane translocase subunit TIM44 OS=Homo sapiens OX=9606 GN=TIMM44 PE=1 SV=2 5.41 3344.7 - 1.67E+06 - - - 1.5205 - 2.652 0.102 - 963.2 1 1 0 0.002 12 0 0 0 1.41E+07 1.64E+07 - - - 2.36 0.8594 221125_WJC_METTL3_EV_vs_WT_F03.20403.20403.3 0.485 Sep-44 R.GLEALLADPQQK.L "sp|Q9H8H0|NOL11_HUMAN,tr|J3QLQ6|J3QLQ6_HUMAN,tr|J3QR28|J3QR28_HUMAN" 3 1281.6929 1.15 35335 20403 3 1281.693281 428.2382 Nucleolar protein 11 OS=Homo sapiens OX=9606 GN=NOL11 PE=1 SV=1 4.37 3345.7 - 275081 - - - 0.3238 - 1.308 0.098 - 106.1 2 2 0 0.0004 12 0 0 0 2.64E+06 2.29E+06 - - - 0.2374 0.9991 221125_WJC_METTL3_EV_vs_WT_F03.20405.20405.2 0.00119 28-Nov K.VFEPNEEALGVVLHK.D "sp|O43615|TIM44_HUMAN,tr|M0QXU7|M0QXU7_HUMAN" 2 1679.8883 2.28 35336 20405 2 1679.886983 840.9514 Mitochondrial import inner membrane translocase subunit TIM44 OS=Homo sapiens OX=9606 GN=TIMM44 PE=1 SV=2 4.75 3345.9 - 1.40E+06 - - - -0.7673 - 1.544 0.337 - 221.8 1 2 0 -0.0013 15 0 0 0 8.44E+06 3.71E+06 - - - 2.5976 0.9992 221125_WJC_METTL3_EV_vs_WT_F03.20407.20407.3 0.0116 Oct-48 R.LVNLQHLDLLNNK[136.11].L sp|Q96AG4|LRC59_HUMAN 1 1540.8817 1.34 35337 20407 3 1540.880797 514.6345 Leucine-rich repeat-containing protein 59 OS=Homo sapiens OX=9606 GN=LRRC59 PE=1 SV=1 6.74 3346.1 - 6.63E+06 - - - -0.5711 - 1.992 0.272 - 98.8 1 2 0 -0.0009 13 0 0 0 1.90E+08 1.41E+08 - - - 3.4407 1 221125_WJC_METTL3_EV_vs_WT_F03.20408.20408.3 4.25E-08 19/88 K.TELAEPIAIRPTSETVMYPAYAK.W sp|P07814|SYEP_HUMAN 1 2550.304 0.89 35338 20408 3 2550.306002 851.1086 Bifunctional glutamate\proline--tRNA ligase OS=Homo sapiens OX=9606 GN=EPRS1 PE=1 SV=5 4.78 3346.2 - 4.23E+06 - - - 0.794 - 2.986 0.546 - 305.5 1 2 0 0.002 23 0 0 0 2.69E+07 3.00E+07 - - - 7.1931 0.9999 221125_WJC_METTL3_EV_vs_WT_F03.20409.20409.2 1.12E-07 26-Nov R.EAGNINQSLLTLGR[166.11].V "sp|P52732|KIF11_HUMAN,tr|A0A7I2YQY4|A0A7I2YQY4_HUMAN,tr|A0A7I2V3A9|A0A7I2V3A9_HUMAN,tr|A0A7I2V3V3|A0A7I2V3V3_HUMAN" 4 1494.803 4.2 35339 20409 2 1494.802282 748.4088 Kinesin-like protein KIF11 OS=Homo sapiens OX=9606 GN=KIF11 PE=1 SV=2 6.1 3346.2 - 2.71E+07 - - - -0.4643 - 2.559 0.528 - 317.4 1 2 0 -0.0007 14 0 0 0 1.13E+09 2.70E+08 - - - 5.2985 1 221125_WJC_METTL3_EV_vs_WT_F03.20410.20410.2 5.70E-09 15/26 K.SAWLSGYENPVVSR.L sp|P13674|P4HA1_HUMAN 1 1563.7682 1.64 35340 20410 2 1563.767945 782.8914 Prolyl 4-hydroxylase subunit alpha-1 OS=Homo sapiens OX=9606 GN=P4HA1 PE=1 SV=2 5.72 3346.3 - 5.38E+06 - - - -0.1356 - 2.785 0.643 - 472.7 1 2 0 -0.0002 14 0 0 0 5.92E+07 3.61E+07 - - - 6.3604 0.9999 221125_WJC_METTL3_EV_vs_WT_F03.20411.20411.3 1.18E-06 Nov-44 K.NKDWVFINYTYK.R sp|Q15208|STK38_HUMAN 1 1589.7878 1.53 35341 20411 3 1589.787705 530.9366 Serine\threonine-protein kinase 38 OS=Homo sapiens OX=9606 GN=STK38 PE=1 SV=1 8.43 3346.3 - 3.99E+06 - - - -0.078 - 2.576 0.488 - 178.2 1 2 1 -0.0001 12 0 0 0 7.62E+07 4.97E+07 - - - 6.6035 1 221125_WJC_METTL3_EV_vs_WT_F03.20412.20412.3 0.00319 16/52 R.RVNQAIWLLC[160.03]TGAR.E "sp|P46782|RS5_HUMAN,tr|M0QZN2|M0QZN2_HUMAN,tr|M0R0F0|M0R0F0_HUMAN,tr|M0R0R2|M0R0R2_HUMAN" 4 1656.8882 1.17 35342 20412 3 1656.887399 553.3034 40S ribosomal protein S5 OS=Homo sapiens OX=9606 GN=RPS5 PE=1 SV=4 10.35 3346.4 - 2.75E+06 - - - -0.5009 - 3.435 0.528 - 461.5 1 2 0 -0.0008 14 0 0 0 2.60E+07 2.21E+07 - - - 7.7059 0.9998 221125_WJC_METTL3_EV_vs_WT_F03.20413.20413.3 0.000513 13/48 K.ALQLEVDR[166.11]LEELK[136.11].M sp|O43663|PRC1_HUMAN 1 1572.8842 0.68 35343 20413 3 1572.882148 525.302 Protein regulator of cytokinesis 1 OS=Homo sapiens OX=9606 GN=PRC1 PE=1 SV=2 4.41 3346.4 - 1.90E+06 - - - -1.3002 - 2.572 0.444 - 196.5 1 2 1 -0.002 13 0 0 0 1.05E+07 1.55E+07 - - - 6.0509 0.9994 221125_WJC_METTL3_EV_vs_WT_F03.20414.20414.2 0.000518 22-Dec K.EGFVEYTEQVVK[136.11].L "sp|O00410|IPO5_HUMAN,sp|O60518|RNBP6_HUMAN,tr|H0Y8C6|H0Y8C6_HUMAN" 3 1434.7122 0.6 35344 20414 2 1434.710966 718.3634 Importin-5 OS=Homo sapiens OX=9606 GN=IPO5 PE=1 SV=4 4.25 3346.5 - 1.59E+06 - - - -0.8678 - 2.224 0.241 - 363.9 1 2 0 -0.0012 12 0 0 0 8.39E+06 1.41E+07 - - - 2.9237 0.9999 221125_WJC_METTL3_EV_vs_WT_F03.20415.20415.3 2.30E-05 14/48 K.AVEDIHGLFSLSK[136.11].K sp|Q14152|EIF3A_HUMAN 1 1422.7598 1.28 35345 20415 3 1422.756258 475.2606 Eukaryotic translation initiation factor 3 subunit A OS=Homo sapiens OX=9606 GN=EIF3A PE=1 SV=1 5.32 3346.6 - 1.34E+06 - - - -2.5106 - 2.645 0.457 - 189.6 1 2 0 -0.0036 13 0 0 0 4.48E+07 3.51E+07 - - - 6.2713 1 221125_WJC_METTL3_EV_vs_WT_F03.20417.20417.3 0.433 21/44 K.NAAIAVLEELKK.L "sp|O95793|STAU1_HUMAN,tr|Q5JW30|Q5JW30_HUMAN,tr|Q5JW28|Q5JW28_HUMAN" 3 1297.7606 2.01 35347 20417 3 1297.758462 433.5941 Double-stranded RNA-binding protein Staufen homolog 1 OS=Homo sapiens OX=9606 GN=STAU1 PE=1 SV=2 6.14 3346.9 - 1.01E+06 - - - -1.6105 - 3.42 0.447 - 870.3 1 2 0 -0.0021 12 0 0 0 1.58E+08 7.89E+07 - - - 6.9314 1 221125_WJC_METTL3_EV_vs_WT_F03.20418.20418.3 0.00275 17/44 K.NAAIAVLEELK[136.11]K[136.11].L "sp|O95793|STAU1_HUMAN,tr|Q5JW30|Q5JW30_HUMAN,tr|Q5JW28|Q5JW28_HUMAN" 3 1313.789 2.01 35348 20418 3 1313.789252 438.9369 Double-stranded RNA-binding protein Staufen homolog 1 OS=Homo sapiens OX=9606 GN=STAU1 PE=1 SV=2 6.14 3347 - 798318 - - - 0.2283 - 2.96 0.445 - 525.6 1 2 0 0.0003 12 0 0 0 1.58E+08 7.89E+07 - - - 6.5092 1 221125_WJC_METTL3_EV_vs_WT_F03.20421.20421.3 0.000126 15/56 K.VFEPNEEALGVVLHK[136.11].D "sp|O43615|TIM44_HUMAN,tr|M0QXU7|M0QXU7_HUMAN" 2 1687.9025 1.18 35350 20421 3 1687.90076 563.6414 Mitochondrial import inner membrane translocase subunit TIM44 OS=Homo sapiens OX=9606 GN=TIMM44 PE=1 SV=2 4.75 3347.4 - 1.90E+07 - - - -1.0143 - 2.81 0.501 - 298.8 1 2 0 -0.0017 15 0 0 0 2.47E+08 2.10E+08 - - - 6.8211 1 221125_WJC_METTL3_EV_vs_WT_F03.20423.20423.3 2.72E-11 15/52 K.C[160.03]EFQDAYVLLSEK[136.11]K[136.11].L "sp|P10809|CH60_HUMAN,tr|A0A7I2V2X6|A0A7I2V2X6_HUMAN,tr|A0A7I2YQK6|A0A7I2YQK6_HUMAN,tr|A0A7I2V599|A0A7I2V599_HUMAN,tr|A0A7I2YQ71|A0A7I2YQ71_HUMAN,tr|A0A7I2V5M1|A0A7I2V5M1_HUMAN,tr|A0A7I2V5K3|A0A7I2V5K3_HUMAN,tr|A0A7I2V369|A0A7I2V369_HUMAN" 8 1744.8677 1.16 35351 20423 3 1744.867078 582.6298 "60 kDa heat shock protein, mitochondrial OS=Homo sapiens OX=9606 GN=HSPD1 PE=1 SV=2" 4.68 3347.6 - 9.15E+06 - - - -0.341 - 2.895 0.651 - 294.1 1 2 0 -0.0006 14 0 0 0 9.99E+08 8.58E+08 - - - 8.6228 0.9999 221125_WJC_METTL3_EV_vs_WT_F03.20424.20424.2 2.63E-05 20-Oct K.GNQLWEYDPVK.L sp|Q10472|GALT1_HUMAN 1 1347.6459 1.44 35352 20424 2 1347.64494 674.8302 Polypeptide N-acetylgalactosaminyltransferase 1 OS=Homo sapiens OX=9606 GN=GALNT1 PE=1 SV=1 4.37 3347.6 - 2.59E+06 - - - -0.7242 - 2.261 0.52 - 398 1 2 0 -0.001 11 0 0 0 2.65E+07 1.84E+07 - - - 5.0884 0.9998 221125_WJC_METTL3_EV_vs_WT_F03.20425.20425.2 0.0788 16-Sep R.DNLAEDIMR.L "sp|P08670|VIME_HUMAN,tr|B0YJC4|B0YJC4_HUMAN" 2 1075.4968 1.88 35353 20425 2 1075.496523 538.7557 Vimentin OS=Homo sapiens OX=9606 GN=VIM PE=1 SV=4 4.03 3347.7 - 7.62E+06 - - - -0.2659 - 1.897 0.457 - 414.6 1 2 0 -0.0003 9 0 0 0 4.08E+08 2.17E+08 - - - 4.2687 0.9998 221125_WJC_METTL3_EV_vs_WT_F03.20427.20427.2 0.00792 16-Sep R.DNLAEDIMR[166.11].L "sp|P08670|VIME_HUMAN,tr|B0YJC4|B0YJC4_HUMAN" 2 1085.5051 1.88 35355 20427 2 1085.504526 543.7598 Vimentin OS=Homo sapiens OX=9606 GN=VIM PE=1 SV=4 4.03 3347.8 - 4.51E+06 - - - -0.5094 - 2.046 0.397 - 356 1 2 0 -0.0006 9 0 0 0 4.08E+08 2.17E+08 - - - 4.0442 1 221125_WJC_METTL3_EV_vs_WT_F03.20428.20428.2 4.21E-05 14/26 R.QASPNIVIALAGNK.A "sp|P51148|RAB5C_HUMAN,tr|K7ERI8|K7ERI8_HUMAN,tr|K7ENY4|K7ENY4_HUMAN,tr|K7ERQ8|K7ERQ8_HUMAN" 4 1394.7882 1.29 35356 20428 2 1394.7868 698.4014 Ras-related protein Rab-5C OS=Homo sapiens OX=9606 GN=RAB5C PE=1 SV=2 8.75 3347.9 - 4.21E+06 - - - -0.9779 - 3.008 0.547 - 980 1 2 0 -0.0014 14 0 0 0 1.03E+08 7.95E+07 - - - 5.8443 0.9991 221125_WJC_METTL3_EV_vs_WT_F03.20430.20430.3 2.30E-06 Nov-48 K.YVFTDISYSIPHR.E "sp|P82650|RT22_HUMAN,tr|G5E9W7|G5E9W7_HUMAN,tr|A0A7P0MKV3|A0A7P0MKV3_HUMAN,tr|H7C5F2|H7C5F2_HUMAN,tr|H7C5L9|H7C5L9_HUMAN,tr|H7C5H3|H7C5H3_HUMAN" 6 1596.7936 1.12 35358 20430 3 1597.79634 533.2718 "28S ribosomal protein S22, mitochondrial OS=Homo sapiens OX=9606 GN=MRPS22 PE=1 SV=1" 6.74 3347.9 - 3.77E+06 - - - 627.944 - 2.29 0.517 - 151.9 1 2 0 1.0027 13 0 0 0 6.01E+07 5.35E+07 - - - 6.2727 1 221125_WJC_METTL3_EV_vs_WT_F03.20432.20432.3 2.39E-05 13/52 R.QDLMNIAGTTLSSK.L "sp|P78371|TCPB_HUMAN,tr|F8VQ14|F8VQ14_HUMAN,tr|F5GWF6|F5GWF6_HUMAN" 3 1477.7446 0.36 35360 20432 3 1477.743095 493.5888 T-complex protein 1 subunit beta OS=Homo sapiens OX=9606 GN=CCT2 PE=1 SV=4 5.84 3348.1 - 2.83E+06 - - - -1.0482 - 2.64 0.45 - 294 1 2 0 -0.0015 14 0 0 0 2.76E+07 7.57E+07 - - - 6.1365 1 221125_WJC_METTL3_EV_vs_WT_F03.20433.20433.3 5.08E-07 13/52 R.SHIPLAFDPTSIPR.G "sp|Q9Y618|NCOR2_HUMAN,tr|C9J7T7|C9J7T7_HUMAN,tr|C9JE98|C9JE98_HUMAN,tr|C9J0Q5|C9J0Q5_HUMAN,tr|A0A384DVL6|A0A384DVL6_HUMAN" 5 1549.8253 2.6 35361 20433 3 1549.825311 517.6157 Nuclear receptor corepressor 2 OS=Homo sapiens OX=9606 GN=NCOR2 PE=1 SV=3 6.46 3348.1 - 2.62E+06 - - - 0.0219 - 2.309 0.482 - 235 1 2 0 0 14 0 0 0 3.56E+07 1.37E+07 - - - 6.1377 0.9999 221125_WJC_METTL3_EV_vs_WT_F03.20434.20434.2 1.58E-06 22-Dec R.SVYGGEFIQQLK.L sp|Q9NQG5|RPR1B_HUMAN 1 1367.7085 2.78 35362 20434 2 1367.707742 684.8615 Regulation of nuclear pre-mRNA domain-containing protein 1B OS=Homo sapiens OX=9606 GN=RPRD1B PE=1 SV=1 5.72 3348.2 - 2.60E+06 - - - -0.5659 - 2.427 0.522 - 373.2 1 2 0 -0.0008 12 0 0 0 3.65E+07 1.31E+07 - - - 5.2292 0.9999 221125_WJC_METTL3_EV_vs_WT_F03.20435.20435.2 3.49E-05 20-Nov K.FNVWDVGGQDK[136.11].L sp|P62330|ARF6_HUMAN 1 1271.6026 1.08 35363 20435 2 1271.602655 636.8086 ADP-ribosylation factor 6 OS=Homo sapiens OX=9606 GN=ARF6 PE=1 SV=2 4.21 3348.3 - 2.38E+06 - - - 0.0425 - 2.12 0.511 - 415 1 2 0 0.0001 11 0 0 0 3.40E+07 3.15E+07 - - - 4.848 0.9998 221125_WJC_METTL3_EV_vs_WT_F03.20437.20437.3 0.00893 Dec-56 K.LFQFLQAEPHNSLGK[136.11].A "sp|Q6P2E9|EDC4_HUMAN,tr|I3L3M2|I3L3M2_HUMAN,tr|I3L0V0|I3L0V0_HUMAN" 3 1735.9137 1.45 35365 20437 3 1735.913215 579.6452 Enhancer of mRNA-decapping protein 4 OS=Homo sapiens OX=9606 GN=EDC4 PE=1 SV=1 6.75 3348.5 - 1.94E+06 - - - -0.2823 - 2.31 0.366 - 106 1 2 0 -0.0005 15 0 0 0 1.20E+07 8.27E+06 - - - 4.8051 1 221125_WJC_METTL3_EV_vs_WT_F03.20438.20438.3 4.22E-06 Dec-52 R.SHIPLAFDPTSIPR[166.11].G "sp|Q9Y618|NCOR2_HUMAN,tr|C9J7T7|C9J7T7_HUMAN,tr|C9JE98|C9JE98_HUMAN,tr|C9J0Q5|C9J0Q5_HUMAN,tr|A0A384DVL6|A0A384DVL6_HUMAN" 5 1559.8335 2.6 35366 20438 3 1559.834205 520.9518 Nuclear receptor corepressor 2 OS=Homo sapiens OX=9606 GN=NCOR2 PE=1 SV=3 6.46 3348.5 - 1.83E+06 - - - 0.4218 - 2.309 0.531 - 223.9 1 2 0 0.0007 14 0 0 0 3.56E+07 1.37E+07 - - - 6.6838 0.9998 221125_WJC_METTL3_EV_vs_WT_F03.20439.20439.3 0.00158 Dec-56 K.LDITTLTGVPEEHIK.T "sp|O43181|NDUS4_HUMAN,tr|H0Y9M8|H0Y9M8_HUMAN" 2 1664.8985 2.16 35367 20439 3 1664.898093 555.9734 "NADH dehydrogenase [ubiquinone] iron-sulfur protein 4, mitochondrial OS=Homo sapiens OX=9606 GN=NDUFS4 PE=1 SV=1" 4.65 3348.6 - 1.77E+06 - - - -0.2457 - 2.189 0.342 - 167.6 1 2 0 -0.0004 15 0 0 0 1.61E+07 7.45E+06 - - - 4.3971 1 221125_WJC_METTL3_EV_vs_WT_F03.20440.20440.2 3.22E-06 16/30 R.SQGVFQC[160.03]GPASVIGVR.E "sp|Q08188|TGM3_HUMAN,tr|A0A494C0J7|A0A494C0J7_HUMAN" 2 1660.8355 6.14 35368 20440 2 1660.832474 831.425 Protein-glutamine gamma-glutamyltransferase E OS=Homo sapiens OX=9606 GN=TGM3 PE=1 SV=4 7.96 3348.8 - 1.63E+06 - - - -1.837 - 3.184 0.589 - 877.8 1 2 0 -0.0031 16 0 0 0 8.29E+06 1.35E+06 - - - 6.2377 1 221125_WJC_METTL3_EV_vs_WT_F03.20442.20442.2 8.24E-08 18/32 K.ELLELDSVETGGQDSVR[166.11].Q sp|O95429|BAG4_HUMAN 1 1855.9039 0.21 35370 20442 2 1855.902619 928.9592 BAG family molecular chaperone regulator 4 OS=Homo sapiens OX=9606 GN=BAG4 PE=1 SV=1 3.83 3349 - 1.45E+06 - - - -0.6751 - 3.571 0.625 - 1002.8 1 2 0 -0.0013 17 0 0 0 2.59E+06 1.22E+07 - - - 6.7862 0.9957 221125_WJC_METTL3_EV_vs_WT_F03.20444.20444.2 6.01E-05 26-Nov K.DSTYSLSSTLTLSK.A "sp|P01834|IGKC_HUMAN,tr|A0A5H1ZRQ3|A0A5H1ZRQ3_HUMAN" 2 1501.7512 97.6 35371 20444 2 1501.743089 751.8829 Immunoglobulin kappa constant OS=Homo sapiens OX=9606 GN=IGKC PE=1 SV=2 5.83 3349.2 - 2.81E+06 - - - -5.3804 - 1.976 0.482 - 276 1 2 0 -0.0081 14 0 0 0 3.08E+07 3.16E+05 - - - 4.3076 1 221125_WJC_METTL3_EV_vs_WT_F03.20445.20445.2 4.98E-06 18/24 R.LVNLQHLDLLNNK.L sp|Q96AG4|LRC59_HUMAN 1 1532.8675 1.25 35372 20445 2 1532.866502 767.441 Leucine-rich repeat-containing protein 59 OS=Homo sapiens OX=9606 GN=LRRC59 PE=1 SV=1 6.74 3349.3 - 1.74E+06 - - - -0.6361 - 3.719 0.576 - 1355.5 1 2 0 -0.001 13 0 0 0 1.41E+07 1.13E+07 - - - 6.6661 0.9999 221125_WJC_METTL3_EV_vs_WT_F03.20446.20446.2 4.69E-08 14/26 R.QASPNIVIALAGNK[136.11].A "sp|P51148|RAB5C_HUMAN,tr|K7ERI8|K7ERI8_HUMAN,tr|K7ENY4|K7ENY4_HUMAN,tr|K7ERQ8|K7ERQ8_HUMAN" 4 1402.8024 1.29 35373 20446 2 1402.802977 702.4085 Ras-related protein Rab-5C OS=Homo sapiens OX=9606 GN=RAB5C PE=1 SV=2 8.75 3349.4 - 5.54E+06 - - - 0.437 - 3.067 0.484 - 797.6 1 2 0 0.0006 14 0 0 0 1.03E+08 7.95E+07 - - - 5.428 0.9999 221125_WJC_METTL3_EV_vs_WT_F03.20447.20447.2 7.26E-07 20-Nov K.FNVWDVGGQDK.L sp|P62330|ARF6_HUMAN 1 1263.5884 1.08 35374 20447 2 1263.588088 632.8015 ADP-ribosylation factor 6 OS=Homo sapiens OX=9606 GN=ARF6 PE=1 SV=2 4.21 3349.4 - 3.51E+06 - - - -0.2477 - 2.394 0.508 - 413.5 1 2 0 -0.0003 11 0 0 0 3.40E+07 3.15E+07 - - - 5.1546 0.9995 221125_WJC_METTL3_EV_vs_WT_F03.20448.20448.2 0.00418 22-Nov K.ALDQFVNFSEQK.E sp|Q9UQE7|SMC3_HUMAN 1 1424.6936 0.5 35375 20448 2 1424.690127 713.3541 Structural maintenance of chromosomes protein 3 OS=Homo sapiens OX=9606 GN=SMC3 PE=1 SV=2 4.37 3349.5 - 3.15E+06 - - - -2.4342 - 2.158 0.425 - 438.9 1 2 0 -0.0035 12 0 0 0 2.93E+07 5.89E+07 - - - 4.2028 1 221125_WJC_METTL3_EV_vs_WT_F03.20449.20449.2 8.03E-07 16/28 K.MSGGWELELNGTEAK.L "sp|Q07021|C1QBP_HUMAN,tr|I3L3B0|I3L3B0_HUMAN,tr|I3L3Q7|I3L3Q7_HUMAN" 3 1620.7454 1.3 35376 20449 2 1620.744703 811.38 "Complement component 1 Q subcomponent-binding protein, mitochondrial OS=Homo sapiens OX=9606 GN=C1QBP PE=1 SV=1" 4.25 3349.5 - 3.05E+06 - - - -0.4128 - 3.457 0.663 - 993.1 1 2 0 -0.0007 15 0 0 0 7.34E+07 5.63E+07 - - - 6.9873 1 221125_WJC_METTL3_EV_vs_WT_F03.20451.20451.2 2.09E-08 16/22 K.NKDWVFINYTYK.R sp|Q15208|STK38_HUMAN 1 1589.7878 9.1 35378 20451 2 1589.78627 795.9012 Serine\threonine-protein kinase 38 OS=Homo sapiens OX=9606 GN=STK38 PE=1 SV=1 8.43 3349.8 - 1.51E+06 - - - -0.9806 - 3.158 0.632 - 1013.2 1 2 1 -0.0016 12 0 0 0 2.41E+07 2.65E+06 - - - 6.7341 1 221125_WJC_METTL3_EV_vs_WT_F03.20452.20452.2 2.24E-08 20/24 R.LVNLQHLDLLNNK[136.11].L sp|Q96AG4|LRC59_HUMAN 1 1540.8817 1.25 35379 20452 2 1540.882462 771.4481 Leucine-rich repeat-containing protein 59 OS=Homo sapiens OX=9606 GN=LRRC59 PE=1 SV=1 6.74 3349.9 - 1.25E+06 - - - 0.5094 - 3.712 0.64 - 1568.2 1 2 0 0.0008 13 0 0 0 1.44E+07 1.15E+07 - - - 7.134 0.9992 221125_WJC_METTL3_EV_vs_WT_F03.20453.20453.3 0.000482 Dec-60 R.EGLEDKYNLQLNPEWR.M "sp|Q9NWS0|PIHD1_HUMAN,tr|M0QYF4|M0QYF4_HUMAN,tr|M0QXD5|M0QXD5_HUMAN,tr|M0R3A4|M0R3A4_HUMAN,tr|M0R2P8|M0R2P8_HUMAN,tr|M0QYA2|M0QYA2_HUMAN" 6 2002.9749 1.89 35380 20453 3 2002.976271 668.6656 PIH1 domain-containing protein 1 OS=Homo sapiens OX=9606 GN=PIH1D1 PE=1 SV=1 4.41 3350 - 1.23E+06 - - - 0.7069 - 2.421 0.346 - 186 1 2 1 0.0014 16 0 0 0 9.11E+06 4.83E+06 - - - 4.6659 1 221125_WJC_METTL3_EV_vs_WT_F03.20456.20456.2 1.51E-14 18/26 K.C[160.03]EFQDAYVLLSEK[136.11]K[136.11].L "sp|P10809|CH60_HUMAN,tr|A0A7I2V2X6|A0A7I2V2X6_HUMAN,tr|A0A7I2YQK6|A0A7I2YQK6_HUMAN,tr|A0A7I2V599|A0A7I2V599_HUMAN,tr|A0A7I2YQ71|A0A7I2YQ71_HUMAN,tr|A0A7I2V5M1|A0A7I2V5M1_HUMAN,tr|A0A7I2V5K3|A0A7I2V5K3_HUMAN,tr|A0A7I2V369|A0A7I2V369_HUMAN" 8 1744.8677 1.47 35383 20456 2 1744.865863 873.4411 "60 kDa heat shock protein, mitochondrial OS=Homo sapiens OX=9606 GN=HSPD1 PE=1 SV=2" 4.68 3350.4 - 920720 - - - -1.0373 - 3.16 0.735 - 919.5 1 2 0 -0.0018 14 0 0 0 4.87E+07 3.30E+07 - - - 7.3564 1 221125_WJC_METTL3_EV_vs_WT_F03.20459.20459.2 2.73E-10 19/36 K.VLDSGAPIKIPVGPETLGR.L "sp|P06576|ATPB_HUMAN,tr|F8W079|F8W079_HUMAN,tr|H0YH81|H0YH81_HUMAN" 3 1918.0888 4.17 35386 20459 2 1918.087466 960.0517 "ATP synthase subunit beta, mitochondrial OS=Homo sapiens OX=9606 GN=ATP5F1B PE=1 SV=3" 6.04 3350.8 - 868001 - - - -0.6762 - 3.391 0.595 - 521 1 2 1 -0.0013 19 0 0 0 1.11E+07 2.66E+06 - - - 6.4375 0.9999 221125_WJC_METTL3_EV_vs_WT_F03.20465.20465.2 0.00954 15/22 K.NAAIAVLEELKK.L "sp|O95793|STAU1_HUMAN,tr|Q5JW30|Q5JW30_HUMAN,tr|Q5JW28|Q5JW28_HUMAN" 3 1297.7606 2.12 35390 20465 2 1297.759452 649.8876 Double-stranded RNA-binding protein Staufen homolog 1 OS=Homo sapiens OX=9606 GN=STAU1 PE=1 SV=2 6.14 3351.4 - 4.30E+06 - - - -0.8476 - 3.056 0.386 - 932.3 1 2 0 -0.0011 12 0 0 0 4.94E+07 2.32E+07 - - - 4.8309 1 221125_WJC_METTL3_EV_vs_WT_F03.20466.20466.2 7.37E-10 14/28 K.MSGGWELELNGTEAK[136.11].L "sp|Q07021|C1QBP_HUMAN,tr|I3L3B0|I3L3B0_HUMAN,tr|I3L3Q7|I3L3Q7_HUMAN" 3 1628.7596 1.3 35391 20466 2 1628.758756 815.3871 "Complement component 1 Q subcomponent-binding protein, mitochondrial OS=Homo sapiens OX=9606 GN=C1QBP PE=1 SV=1" 4.25 3351.5 - 4.74E+06 - - - -0.501 - 3.051 0.648 - 655.7 1 2 0 -0.0008 15 0 0 0 7.34E+07 5.63E+07 - - - 6.5693 0.9995 221125_WJC_METTL3_EV_vs_WT_F03.20471.20471.2 0.00305 20-Dec R.ADLEMQIENLK.E "sp|Q04695|K1C17_HUMAN,tr|K7EPJ9|K7EPJ9_HUMAN,tr|F5GWP8|F5GWP8_HUMAN" 3 1302.649 31.7 35396 20471 2 1302.647492 652.3318 "Keratin, type I cytoskeletal 17 OS=Homo sapiens OX=9606 GN=KRT17 PE=1 SV=2" 4.14 3351.8 - 2.33E+06 - - - -1.1216 - 2.656 0.205 - 826.5 1 2 0 -0.0015 11 0 0 0 6.44E+07 2.03E+06 - - - 3.1972 1 221125_WJC_METTL3_EV_vs_WT_F03.20473.20473.2 3.52E-12 16/34 K.SLPGQNEDLVLTGYQVDK.N sp|P01040|CYTA_HUMAN 1 1974.9898 999 35398 20473 2 1974.986762 988.5022 Cystatin-A OS=Homo sapiens OX=9606 GN=CSTA PE=1 SV=1 4.03 3352 - 1.06E+06 - - - -1.5565 - 3.363 0.68 - 843.8 1 2 0 -0.0031 18 0 0 0 9.57E+07 0.00E+00 - - - 7.0443 0.9994 221125_WJC_METTL3_EV_vs_WT_F03.20474.20474.3 0.111 15/40 K.ISRDELLQVLR.M sp|Q99653|CHP1_HUMAN 1 1340.7776 1.56 35399 20474 3 1340.777792 447.9331 Calcineurin B homologous protein 1 OS=Homo sapiens OX=9606 GN=CHP1 PE=1 SV=3 6.07 3352.1 - 968069 - - - 0.1439 - 2.71 0.326 - 534.5 1 2 1 0.0002 11 0 0 0 6.50E+06 4.17E+06 - - - 5.0067 0.9982 221125_WJC_METTL3_EV_vs_WT_F03.20476.20476.2 5.23E-05 Nov-36 K.VLDSGAPIK[136.11]IPVGPETLGR[166.11].L "sp|P06576|ATPB_HUMAN,tr|F8W079|F8W079_HUMAN,tr|H0YH81|H0YH81_HUMAN" 3 1936.1112 4.17 35401 20476 2 1936.113846 969.0629 "ATP synthase subunit beta, mitochondrial OS=Homo sapiens OX=9606 GN=ATP5F1B PE=1 SV=3" 6.04 3352.4 - 481877 - - - 1.3496 - 2.342 0.543 - 146.5 1 2 1 0.0026 19 0 0 0 1.11E+07 2.66E+06 - - - 5.143 0.9996 221125_WJC_METTL3_EV_vs_WT_F03.20484.20484.3 0.0065 Dec-68 K.SLPGQNEDLVLTGYQVDK.N sp|P01040|CYTA_HUMAN 1 1974.9898 50.56 35407 20484 3 1974.986968 659.3372 Cystatin-A OS=Homo sapiens OX=9606 GN=CSTA PE=1 SV=1 4.03 3353.2 - 3.37E+06 - - - -1.4522 - 2.119 0.33 - 165.4 1 2 0 -0.0029 18 0 0 0 7.46E+07 1.48E+06 - - - 4.0883 0.9999 221125_WJC_METTL3_EV_vs_WT_F03.20487.20487.3 0.00897 13/48 K.FLSPQDTFEALK[136.11]R[166.11].N sp|Q9NTZ6|RBM12_HUMAN 1 1568.8318 1.18 35410 20487 3 1568.832584 523.9512 RNA-binding protein 12 OS=Homo sapiens OX=9606 GN=RBM12 PE=1 SV=1 6.07 3353.4 - 1.48E+06 - - - 0.5233 - 2.469 0.424 - 164.7 1 2 0 0.0008 13 0 0 0 2.47E+07 2.10E+07 - - - 5.7175 0.9998 221125_WJC_METTL3_EV_vs_WT_F03.20488.20488.3 0.000165 13/52 K.LYLIDLAGSEDNR[166.11]R[166.11].T "sp|Q14807|KIF22_HUMAN,tr|H3BRB3|H3BRB3_HUMAN" 2 1653.8589 1.39 35411 20488 3 1653.856477 552.2936 Kinesin-like protein KIF22 OS=Homo sapiens OX=9606 GN=KIF22 PE=1 SV=5 4.56 3353.6 - 1.47E+06 - - - -1.4796 - 2.119 0.386 - 195.8 1 2 0 -0.0024 14 0 0 0 1.27E+07 9.13E+06 - - - 4.8385 1 221125_WJC_METTL3_EV_vs_WT_F03.20489.20489.2 0.00105 19/30 K.VQLDLAETDLSQGVAR[166.11].W sp|Q9BSJ8|ESYT1_HUMAN 1 1723.898 1 35412 20489 2 1723.899657 862.9563 Extended synaptotagmin-1 OS=Homo sapiens OX=9606 GN=ESYT1 PE=1 SV=1 4.03 3353.7 - 1.33E+06 - - - 0.9624 - 3.577 0.545 - 1228.2 1 2 0 0.0017 16 0 0 0 1.28E+07 1.29E+07 - - - 6.1993 0.9998 221125_WJC_METTL3_EV_vs_WT_F03.20490.20490.3 7.83E-08 17/60 K.VQLDLAETDLSQGVAR.W sp|Q9BSJ8|ESYT1_HUMAN 1 1713.8897 1.34 35413 20490 3 1713.896611 572.3039 Extended synaptotagmin-1 OS=Homo sapiens OX=9606 GN=ESYT1 PE=1 SV=1 4.03 3353.8 - 898881 - - - 4.016 - 2.984 0.499 - 361.4 1 2 0 0.0069 16 0 0 0 1.03E+07 7.68E+06 - - - 6.9066 0.9983 221125_WJC_METTL3_EV_vs_WT_F03.20491.20491.2 7.46E-06 22-Oct K.EFTVNIMDTC[160.03]ER.C "sp|Q96EY1|DNJA3_HUMAN,tr|I3L1T6|I3L1T6_HUMAN" 2 1513.6541 0.97 35414 20491 2 1513.661138 757.8343 "DnaJ homolog subfamily A member 3, mitochondrial OS=Homo sapiens OX=9606 GN=DNAJA3 PE=1 SV=2" 4.14 3353.9 - 780928 - - - 4.6398 - 2.039 0.557 - 383.1 1 2 0 0.007 12 0 0 0 4.67E+06 4.80E+06 - - - 5.0274 0.9992 221125_WJC_METTL3_EV_vs_WT_F03.20494.20494.2 0.00233 26-Oct R.LQDSFASETNLDFR[166.11].S sp|Q92621|NU205_HUMAN 1 1651.7717 0.31 35417 20494 2 1651.768175 826.8931 Nuclear pore complex protein Nup205 OS=Homo sapiens OX=9606 GN=NUP205 PE=1 SV=3 4.03 3354.3 - 550656 - - - -2.1553 - 1.903 0.373 - 179.2 1 2 0 -0.0036 14 0 0 0 2.78E+06 9.02E+06 - - - 3.4095 0.9885 221125_WJC_METTL3_EV_vs_WT_F03.20498.20498.2 8.59E-07 26-Dec R.QDLMNIAGTTLSSK[136.11].L "sp|P78371|TCPB_HUMAN,tr|F8VQ14|F8VQ14_HUMAN,tr|F5GWF6|F5GWF6_HUMAN" 3 1485.7588 1.61 35419 20498 2 1485.74779 743.8867 T-complex protein 1 subunit beta OS=Homo sapiens OX=9606 GN=CCT2 PE=1 SV=4 5.84 3354.8 - 7.04E+06 - - - -7.44 - 2.71 0.456 - 537 1 2 0 -0.0111 14 0 0 0 1.46E+08 9.05E+07 - - - 4.9073 0.9999 221125_WJC_METTL3_EV_vs_WT_F03.20502.20502.3 5.53E-06 Dec-56 K.SIYGEKFEDENFILK.H "sp|P62937|PPIA_HUMAN,tr|C9J5S7|C9J5S7_HUMAN,tr|A0A7I2V4V1|A0A7I2V4V1_HUMAN,tr|F8WE65|F8WE65_HUMAN" 4 1830.904 1.08 35423 20502 3 1830.904174 611.3086 Peptidyl-prolyl cis-trans isomerase A OS=Homo sapiens OX=9606 GN=PPIA PE=1 SV=2 4.41 3355 - 2.52E+06 - - - 0.1054 - 2.203 0.526 - 96.6 1 2 1 0.0002 15 0 0 0 1.38E+08 1.28E+08 - - - 6.4653 0.9994 221125_WJC_METTL3_EV_vs_WT_F03.20503.20503.3 5.97E-06 Dec-56 K.SIYGEK[136.11]FEDENFILK[136.11].H "sp|P62937|PPIA_HUMAN,tr|C9J5S7|C9J5S7_HUMAN,tr|A0A7I2V4V1|A0A7I2V4V1_HUMAN,tr|F8WE65|F8WE65_HUMAN" 4 1846.9324 1.08 35424 20503 3 1846.931232 616.6514 Peptidyl-prolyl cis-trans isomerase A OS=Homo sapiens OX=9606 GN=PPIA PE=1 SV=2 4.41 3355 - 2.51E+06 - - - -0.6221 - 1.931 0.419 - 91 1 2 1 -0.0011 15 0 0 0 1.38E+08 1.28E+08 - - - 4.9282 0.9914 221125_WJC_METTL3_EV_vs_WT_F03.20504.20504.2 5.51E-07 28-Dec K.SGDAAIVDMVPGK[136.11]PM.C "sp|P68104|EF1A1_HUMAN,sp|Q5VTE0|EF1A3_HUMAN,tr|A0A7I2V659|A0A7I2V659_HUMAN,tr|A0A7I2V5N4|A0A7I2V5N4_HUMAN,tr|A0A087WVQ9|A0A087WVQ9_HUMAN,tr|A0A087WV01|A0A087WV01_HUMAN" 6 1494.7302 0.39 35425 20504 2 1494.728958 748.3724 Elongation factor 1-alpha 1 OS=Homo sapiens OX=9606 GN=EEF1A1 PE=1 SV=1 4.21 3355.2 - 1.49E+06 - - - -0.8216 - 2.259 0.502 - 254 1 1 0 -0.0012 15 0 0 0 1.14E+07 2.92E+07 - - - 4.7519 0.9961 221125_WJC_METTL3_EV_vs_WT_F03.20506.20506.2 0.000356 16-Oct R.RGFC[160.03]FITFK.E "sp|Q14103|HNRPD_HUMAN,tr|H0Y8G5|H0Y8G5_HUMAN,tr|H0YA96|H0YA96_HUMAN" 3 1174.5957 0.94 35427 20506 2 1174.591951 588.3051 Heterogeneous nuclear ribonucleoprotein D0 OS=Homo sapiens OX=9606 GN=HNRNPD PE=1 SV=1 9.51 3355.4 - 1.03E+06 - - - -3.2215 - 1.926 0.229 - 326 1 2 0 -0.0038 9 0 0 0 1.54E+07 1.64E+07 - - - 2.6274 0.9995 221125_WJC_METTL3_EV_vs_WT_F03.20507.20507.3 2.66E-05 13/44 R.AR[166.11]FEELNADLFR[166.11].G "sp|P54652|HSP72_HUMAN,sp|P11142|HSP7C_HUMAN,tr|E9PNE6|E9PNE6_HUMAN,tr|A8K7Q2|A8K7Q2_HUMAN,tr|E9PKE3|E9PKE3_HUMAN,tr|E9PN89|E9PN89_HUMAN" 6 1499.7636 1.38 35428 20507 3 1499.762543 500.9285 Heat shock-related 70 kDa protein 2 OS=Homo sapiens OX=9606 GN=HSPA2 PE=1 SV=1 4.68 3355.5 - 953190 - - - -0.6828 - 2.326 0.378 - 271.2 1 2 1 -0.001 12 0 0 0 1.11E+07 8.04E+06 - - - 5.0939 1 221125_WJC_METTL3_EV_vs_WT_F03.20508.20508.3 1.52E-06 14/60 K.LPPSLGNKPVLPLIGK.L sp|Q9UKJ3|GPTC8_HUMAN 1 1642.0182 0.76 35429 20508 3 1642.019119 548.3467 G patch domain-containing protein 8 OS=Homo sapiens OX=9606 GN=GPATCH8 PE=1 SV=2 10 3355.6 - 872811 - - - 0.5816 - 3.054 0.561 - 199.6 1 2 0 0.001 16 0 0 0 8.66E+06 1.14E+07 - - - 7.659 0.9994 221125_WJC_METTL3_EV_vs_WT_F03.20510.20510.3 0.000142 Dec-32 K.QDILTIFK[136.11]R[166.11].L "sp|Q9NP61|ARFG3_HUMAN,tr|B0QYV8|B0QYV8_HUMAN" 2 1150.6829 0.001 35431 20510 3 1150.681873 384.5682 ADP-ribosylation factor GTPase-activating protein 3 OS=Homo sapiens OX=9606 GN=ARFGAP3 PE=1 SV=1 8.75 3355.9 - 595015 - - - -0.9047 - 2.2 0.247 - 184.1 1 2 0 -0.001 9 0 0 0 0.00E+00 7.40E+06 - - - 3.6698 1 221125_WJC_METTL3_EV_vs_WT_F03.20517.20517.3 2.84E-05 14/48 K.MFIGGLSWDTSKK.D "sp|O14979|HNRDL_HUMAN,tr|A0A087WUK2|A0A087WUK2_HUMAN" 2 1468.7384 0.97 35436 20517 3 1468.738962 490.5868 Heterogeneous nuclear ribonucleoprotein D-like OS=Homo sapiens OX=9606 GN=HNRNPDL PE=1 SV=3 8.35 3356.6 - 5.20E+06 - - - 0.3581 - 2.754 0.493 - 252.3 1 2 0 0.0005 13 0 0 0 1.01E+08 1.04E+08 - - - 6.783 0.9978 221125_WJC_METTL3_EV_vs_WT_F03.20519.20519.3 0.00103 Sep-40 K.RLWGDIYFNPK.T sp|Q15029|U5S1_HUMAN 1 1407.7299 1.49 35438 20519 3 1407.730266 470.2506 116 kDa U5 small nuclear ribonucleoprotein component OS=Homo sapiens OX=9606 GN=EFTUD2 PE=1 SV=1 8.59 3356.7 - 1.75E+06 - - - 0.2458 - 1.945 0.21 - 101.1 1 2 0 0.0003 11 0 0 0 2.05E+07 1.37E+07 - - - 2.7711 0.9999 221125_WJC_METTL3_EV_vs_WT_F03.20521.20521.2 0.026 16/30 K.VQLDLAETDLSQGVAR.W sp|Q9BSJ8|ESYT1_HUMAN 1 1713.8897 1 35440 20521 2 1713.890458 857.9521 Extended synaptotagmin-1 OS=Homo sapiens OX=9606 GN=ESYT1 PE=1 SV=1 4.03 3357 - 1.19E+06 - - - 0.4259 - 3.065 0.416 - 717.7 1 2 0 0.0007 16 0 0 0 1.28E+07 1.29E+07 - - - 4.867 0.9991 221125_WJC_METTL3_EV_vs_WT_F03.20522.20522.3 0.00013 14/40 K.SDKLVYVDLLR.E "sp|Q6W2J9|BCOR_HUMAN,tr|H7BZ37|H7BZ37_HUMAN,tr|A1A564|A1A564_HUMAN,tr|H7C2V9|H7C2V9_HUMAN,tr|H7BYY2|H7BYY2_HUMAN,tr|H7C231|H7C231_HUMAN" 6 1319.7449 0.79 35441 20522 3 1319.749559 440.9222 BCL-6 corepressor OS=Homo sapiens OX=9606 GN=BCOR PE=1 SV=1 5.68 3357.1 - 1.05E+06 - - - 3.5287 - 2.551 0.465 - 350.2 1 2 1 0.0047 11 0 0 0 9.19E+06 1.17E+07 - - - 6.3834 1 221125_WJC_METTL3_EV_vs_WT_F03.20524.20524.3 6.57E-07 15/48 K.R[166.11]PVSAMFIFSEEK[136.11].R "sp|P17480|UBF1_HUMAN,tr|E9PKP7|E9PKP7_HUMAN" 2 1557.798 1.39 35443 20524 3 1557.7987 520.2733 Nucleolar transcription factor 1 OS=Homo sapiens OX=9606 GN=UBTF PE=1 SV=1 6.14 3357.4 - 911928 - - - 0.4365 - 2.51 0.477 - 239.3 1 2 0 0.0007 13 0 0 0 8.90E+06 6.41E+06 - - - 6.353 0.9588 221125_WJC_METTL3_EV_vs_WT_F03.20526.20526.2 6.53E-09 18/28 K.SIYGEKFEDENFILK.H "sp|P62937|PPIA_HUMAN,tr|C9J5S7|C9J5S7_HUMAN,tr|A0A7I2V4V1|A0A7I2V4V1_HUMAN,tr|F8WE65|F8WE65_HUMAN" 4 1830.904 2.72 35445 20526 2 1830.911768 916.4593 Peptidyl-prolyl cis-trans isomerase A OS=Homo sapiens OX=9606 GN=PPIA PE=1 SV=2 4.41 3357.6 - 782296 - - - 4.2531 - 3.097 0.222 - 758.6 1 2 1 0.0078 15 0 0 0 1.05E+07 3.88E+06 - - - 3.4575 1 221125_WJC_METTL3_EV_vs_WT_F03.20531.20531.2 7.98E-07 14/24 R.GNPTVEVDLFTSK.G "sp|P06733|ENOA_HUMAN,tr|A0A2R8Y6G6|A0A2R8Y6G6_HUMAN,tr|A0A2R8YEG5|A0A2R8YEG5_HUMAN,tr|K7ERS8|K7ERS8_HUMAN,tr|K7EM90|K7EM90_HUMAN,tr|A0A2R8Y879|A0A2R8Y879_HUMAN,tr|A0A2R8Y798|A0A2R8Y798_HUMAN,tr|A0A2R8YEM5|A0A2R8YEM5_HUMAN" 8 1405.7089 1.6 35448 20531 2 1405.709121 703.8617 Alpha-enolase OS=Homo sapiens OX=9606 GN=ENO1 PE=1 SV=2 4.37 3358.2 - 7.22E+06 - - - 0.1501 - 2.595 0.609 - 941.8 1 2 0 0.0002 13 0 0 0 3.85E+08 2.40E+08 - - - 5.9864 1 221125_WJC_METTL3_EV_vs_WT_F03.20533.20533.2 8.11E-07 20/32 R.LSASSSISSADLFEEPR.K "sp|Q9NP61|ARFG3_HUMAN,tr|H0Y6A0|H0Y6A0_HUMAN" 2 1794.8636 1.19 35450 20533 2 1794.861705 898.4391 ADP-ribosylation factor GTPase-activating protein 3 OS=Homo sapiens OX=9606 GN=ARFGAP3 PE=1 SV=1 4.14 3358.4 - 1.66E+06 - - - -1.0407 - 3.639 0.6 - 1189.2 1 2 0 -0.0019 17 0 0 0 1.21E+08 1.02E+08 - - - 6.6477 0.9987 221125_WJC_METTL3_EV_vs_WT_F03.20534.20534.3 6.63E-07 20/64 R.TPVDFYPSALHPSGLMK.P sp|Q5JSZ5|PRC2B_HUMAN 1 1858.9288 1.79 35451 20534 3 1858.930568 620.6502 Protein PRRC2B OS=Homo sapiens OX=9606 GN=PRRC2B PE=1 SV=2 6.41 3358.5 - 1.29E+06 - - - 0.9748 - 3.863 0.551 - 483.6 1 1 0 0.0018 17 0 0 0 1.95E+07 1.09E+07 - - - 8.0968 0.9998 221125_WJC_METTL3_EV_vs_WT_F03.20536.20536.2 0.0615 14/24 K.AIELFSVGQGPAK[136.11].T "sp|P30419|NMT1_HUMAN,tr|A0A7I2V4Y5|A0A7I2V4Y5_HUMAN,tr|B7Z8J4|B7Z8J4_HUMAN,tr|K7EN82|K7EN82_HUMAN,tr|A0A7I2V3X4|A0A7I2V3X4_HUMAN,tr|A0A7I2V539|A0A7I2V539_HUMAN,tr|A0A7I2V3U5|A0A7I2V3U5_HUMAN" 7 1323.7278 0.29 35453 20536 2 1323.729437 662.8712 Glycylpeptide N-tetradecanoyltransferase 1 OS=Homo sapiens OX=9606 GN=NMT1 PE=1 SV=2 6.05 3358.8 - 1.17E+06 - - - 1.2351 - 2.762 0.389 - 718.9 1 2 0 0.0016 13 0 0 0 6.70E+06 2.30E+07 - - - 4.5211 1 221125_WJC_METTL3_EV_vs_WT_F03.20538.20538.3 7.05E-07 14/44 R.KADVEEEFLALR.K "sp|P46013|KI67_HUMAN,sp|P46013|KI67_HUMAN" 2 1418.7405 1.32 35455 20538 3 1418.739782 473.9208 Proliferation marker protein Ki-67 OS=Homo sapiens OX=9606 GN=MKI67 PE=1 SV=2 4.41 3359 - 928637 - - - -0.5378 - 2.489 0.509 - 246.2 1 2 0 -0.0008 12 0 0 0 8.83E+06 6.67E+06 - - - 6.7422 0.9999 221125_WJC_METTL3_EV_vs_WT_F03.20540.20540.3 1.74E-05 14/40 K.DGLAFNALIHR[166.11].H "sp|O43707|ACTN4_HUMAN,sp|Q9H254|SPTN4_HUMAN,tr|C9JY79|C9JY79_HUMAN,tr|M0QZQ3|M0QZQ3_HUMAN,tr|F5GXS2|F5GXS2_HUMAN,tr|H7C144|H7C144_HUMAN" 6 1235.665 0.97 35457 20540 3 1235.665154 412.8956 Alpha-actinin-4 OS=Homo sapiens OX=9606 GN=ACTN4 PE=1 SV=2 6.74 3359.3 - 622882 - - - 0.1044 - 2.425 0.346 - 252.6 1 2 0 0.0001 11 0 0 0 1.01E+07 1.04E+07 - - - 4.914 0.9985 221125_WJC_METTL3_EV_vs_WT_F03.20541.20541.2 0.00669 26-Oct K.VEPSDNGPLFTELK[136.11].F "sp|Q99986|VRK1_HUMAN,tr|A0A7P0T814|A0A7P0T814_HUMAN,tr|A0A7P0T838|A0A7P0T838_HUMAN,tr|H0YJJ9|H0YJJ9_HUMAN,tr|A0A7P0TA16|A0A7P0TA16_HUMAN,tr|A0A7P0T8N0|A0A7P0T8N0_HUMAN,tr|H0YJF7|H0YJF7_HUMAN,tr|A0A7P0T9T1|A0A7P0T9T1_HUMAN,tr|A0A7P0Z4C8|A0A7P0Z4C8_HUMAN,tr|A0A7P0Z4A4|A0A7P0Z4A4_HUMAN,tr|A0A7P0Z445|A0A7P0Z445_HUMAN,tr|A0A7P0TAA6|A0A7P0TAA6_HUMAN,tr|A0A7P0T832|A0A7P0T832_HUMAN,tr|A0A7P0T9B1|A0A7P0T9B1_HUMAN,tr|A0A7P0TBB8|A0A7P0TBB8_HUMAN,tr|A0A7P0Z462|A0A7P0Z462_HUMAN,tr|A0A7P0TBE4|A0A7P0TBE4_HUMAN,tr|A0A7P0TB08|A0A7P0TB08_HUMAN,tr|A0A7P0TA65|A0A7P0TA65_HUMAN,tr|A0A7P0T824|A0A7P0T824_HUMAN,tr|A0A7P0T9I1|A0A7P0T9I1_HUMAN,tr|A0A7P0T977|A0A7P0T977_HUMAN,tr|A0A7P0T8M0|A0A7P0T8M0_HUMAN,tr|A0A7P0Z3Z7|A0A7P0Z3Z7_HUMAN,tr|A0A7P0TAS8|A0A7P0TAS8_HUMAN,tr|A0A7P0T9C6|A0A7P0T9C6_HUMAN,tr|A0A7P0TBI6|A0A7P0TBI6_HUMAN,tr|A0A7P0TB15|A0A7P0TB15_HUMAN,tr|A0A7P0T8Z5|A0A7P0T8Z5_HUMAN,tr|A0A7P0T952|A0A7P0T952_HUMAN" 30 1552.7864 0.21 35458 20541 2 1552.792384 777.4005 Serine\threonine-protein kinase VRK1 OS=Homo sapiens OX=9606 GN=VRK1 PE=1 SV=1 4.14 3359.4 - 537808 - - - 3.8286 - 2.224 0.435 - 191.8 1 2 0 0.0059 14 0 0 0 1.10E+07 5.15E+07 - - - 4.2579 0.9997 221125_WJC_METTL3_EV_vs_WT_F03.20542.20542.3 0.00132 Sep-32 R.R[166.11]GFC[160.03]FITFK[136.11].E "sp|Q14103|HNRPD_HUMAN,tr|H0Y8G5|H0Y8G5_HUMAN,tr|H0YA96|H0YA96_HUMAN" 3 1192.6182 1.16 35459 20542 3 1192.618866 398.5467 Heterogeneous nuclear ribonucleoprotein D0 OS=Homo sapiens OX=9606 GN=HNRNPD PE=1 SV=1 9.51 3359.5 - 500544 - - - 0.5542 - 1.75 0.361 - 127.7 1 2 0 0.0007 9 0 0 0 5.98E+06 5.16E+06 - - - 4.2512 1 221125_WJC_METTL3_EV_vs_WT_F03.20544.20544.2 2.41E-07 18/36 R.ILSAENIPNLPPGGGLAGK.R "sp|O75688|PPM1B_HUMAN,tr|B8ZZF0|B8ZZF0_HUMAN,tr|A0A3B3IS24|A0A3B3IS24_HUMAN,tr|C9JIR6|C9JIR6_HUMAN" 4 1817.0047 3.63 35460 20544 2 1817.004074 909.5096 Protein phosphatase 1B OS=Homo sapiens OX=9606 GN=PPM1B PE=1 SV=1 6 3359.7 - 9.20E+06 - - - -0.344 - 3.182 0.564 - 540.8 1 2 0 -0.0006 19 0 0 0 1.80E+08 4.97E+07 - - - 6.0523 1 221125_WJC_METTL3_EV_vs_WT_F03.20545.20545.2 8.97E-06 17/32 R.LSASSSISSADLFEEPR[166.11].K "sp|Q9NP61|ARFG3_HUMAN,tr|H0Y6A0|H0Y6A0_HUMAN" 2 1804.8718 1.19 35461 20545 2 1804.867252 903.4432 ADP-ribosylation factor GTPase-activating protein 3 OS=Homo sapiens OX=9606 GN=ARFGAP3 PE=1 SV=1 4.14 3359.8 - 2.42E+06 - - - -2.5437 - 3.405 0.588 - 839 1 2 0 -0.0046 17 0 0 0 1.21E+08 1.02E+08 - - - 6.3948 1 221125_WJC_METTL3_EV_vs_WT_F03.20546.20546.2 1.40E-09 24-Dec R.GNPTVEVDLFTSK[136.11].G "sp|P06733|ENOA_HUMAN,tr|A0A2R8Y6G6|A0A2R8Y6G6_HUMAN,tr|A0A2R8YEG5|A0A2R8YEG5_HUMAN,tr|K7ERS8|K7ERS8_HUMAN,tr|K7EM90|K7EM90_HUMAN,tr|A0A2R8Y879|A0A2R8Y879_HUMAN,tr|A0A2R8Y798|A0A2R8Y798_HUMAN,tr|A0A2R8YEM5|A0A2R8YEM5_HUMAN" 8 1413.7231 1.6 35462 20546 2 1413.723398 707.8688 Alpha-enolase OS=Homo sapiens OX=9606 GN=ENO1 PE=1 SV=2 4.37 3359.9 - 1.24E+07 - - - 0.2037 - 2.493 0.658 - 662 1 2 0 0.0003 13 0 0 0 3.85E+08 2.40E+08 - - - 6.2454 1 221125_WJC_METTL3_EV_vs_WT_F03.20548.20548.3 5.16E-06 Dec-44 K.NLLHQDAVDLFR.N "sp|P57105|SYJ2B_HUMAN,tr|A0A087X1F5|A0A087X1F5_HUMAN,tr|A0A087WYV9|A0A087WYV9_HUMAN" 3 1439.7521 1.36 35464 20548 3 1439.751913 480.9246 Synaptojanin-2-binding protein OS=Homo sapiens OX=9606 GN=SYNJ2BP PE=1 SV=2 5.21 3359.9 - 4.61E+06 - - - -0.1389 - 2.18 0.493 - 230.6 1 2 0 -0.0002 12 0 0 0 4.31E+07 3.18E+07 - - - 6.1966 0.9978 221125_WJC_METTL3_EV_vs_WT_F03.20550.20550.3 2.28E-06 14/44 Q.ISALEEQLQQIR.A "sp|P13645|K1C10_HUMAN,tr|A0A1B0GVI3|A0A1B0GVI3_HUMAN" 2 1426.778 337.94 35466 20550 3 1426.77871 476.5999 "Keratin, type I cytoskeletal 10 OS=Homo sapiens OX=9606 GN=KRT10 PE=1 SV=6" 4.53 3360 - 3.10E+06 - - - 0.5025 - 2.954 0.488 - 311.3 1 1 0 0.0007 12 0 0 0 5.25E+07 1.55E+05 - - - 6.9829 0.9999 221125_WJC_METTL3_EV_vs_WT_F03.20551.20551.3 0.00464 13/48 K.AVDIPHMDIEALK[136.11].K sp|P62906|RL10A_HUMAN 1 1458.7632 1.24 35467 20551 3 1458.762562 487.2617 60S ribosomal protein L10a OS=Homo sapiens OX=9606 GN=RPL10A PE=1 SV=2 4.54 3360.1 - 2.39E+06 - - - -0.438 - 2.3 0.454 - 205.1 1 2 0 -0.0006 13 0 0 0 1.99E+08 1.61E+08 - - - 5.8597 0.9979 221125_WJC_METTL3_EV_vs_WT_F03.20552.20552.2 0.00013 16-Sep R.DVTTFFSGK.A "sp|Q8N6T3|ARFG1_HUMAN,tr|F8VWH9|F8VWH9_HUMAN,tr|F8W1U7|F8W1U7_HUMAN,tr|E5RHH7|E5RHH7_HUMAN" 4 1000.4866 1.3 35468 20552 2 1000.48272 501.2506 ADP-ribosylation factor GTPase-activating protein 1 OS=Homo sapiens OX=9606 GN=ARFGAP1 PE=1 SV=2 5.84 3360.2 - 2.01E+06 - - - -3.8401 - 1.605 0.456 - 231.5 1 2 0 -0.0038 9 0 0 0 5.46E+07 4.21E+07 - - - 3.7766 0.9999 221125_WJC_METTL3_EV_vs_WT_F03.20555.20555.3 0.000119 13/40 K.DGLAFNALIHR.H "sp|O43707|ACTN4_HUMAN,sp|Q9H254|SPTN4_HUMAN,tr|C9JY79|C9JY79_HUMAN,tr|M0QZQ3|M0QZQ3_HUMAN,tr|F5GXS2|F5GXS2_HUMAN,tr|H7C144|H7C144_HUMAN" 6 1225.6568 0.97 35471 20555 3 1225.65501 409.5595 Alpha-actinin-4 OS=Homo sapiens OX=9606 GN=ACTN4 PE=1 SV=2 6.74 3360.5 - 915507 - - - -1.4237 - 2.388 0.409 - 210.2 1 2 0 -0.0017 11 0 0 0 1.01E+07 1.04E+07 - - - 5.5723 1 221125_WJC_METTL3_EV_vs_WT_F03.20556.20556.2 1.24E-08 15/32 R.FSPNSSNPIIVSC[160.03]GWDK[136.11].L "sp|P63244|RACK1_HUMAN,tr|H0YAM7|H0YAM7_HUMAN,tr|D6RFX4|D6RFX4_HUMAN,tr|H0YAF8|H0YAF8_HUMAN,tr|D6R9Z1|D6R9Z1_HUMAN,tr|J3KPE3|J3KPE3_HUMAN,tr|D6R9L0|D6R9L0_HUMAN,tr|D6RHH4|D6RHH4_HUMAN,tr|D6RBD0|D6RBD0_HUMAN,tr|D6RAC2|D6RAC2_HUMAN,tr|H0Y8R5|H0Y8R5_HUMAN,tr|D6REE5|D6REE5_HUMAN,tr|H0Y8W2|H0Y8W2_HUMAN" 13 1914.9025 1.31 35472 20556 2 1914.907796 958.4586 Receptor of activated protein C kinase 1 OS=Homo sapiens OX=9606 GN=RACK1 PE=1 SV=3 5.83 3360.6 - 743780 - - - 2.7406 - 3.013 0.67 - 544.4 1 2 0 0.0052 17 0 0 0 2.38E+07 1.82E+07 - - - 6.6996 0.9997 221125_WJC_METTL3_EV_vs_WT_F03.20557.20557.3 1.99E-05 13/40 R.LGLHQVLQDLR.E "sp|O60610|DIAP1_HUMAN,tr|A0A2R8Y5N1|A0A2R8Y5N1_HUMAN,tr|A0A140T8Z0|A0A140T8Z0_HUMAN,tr|A0A0G2JH68|A0A0G2JH68_HUMAN,tr|H9KV28|H9KV28_HUMAN" 5 1290.7408 0.93 35473 20557 3 1290.744229 431.2542 Protein diaphanous homolog 1 OS=Homo sapiens OX=9606 GN=DIAPH1 PE=1 SV=2 6.74 3360.7 - 506756 - - - 2.6411 - 2.642 0.348 - 225.8 1 2 0 0.0034 11 0 0 0 6.29E+06 6.75E+06 - - - 5.1789 0.9831 221125_WJC_METTL3_EV_vs_WT_F03.20558.20558.2 5.43E-06 26-Dec R.AELQAQVAFLQGER.K "sp|Q9NRL3|STRN4_HUMAN,tr|M0R0W8|M0R0W8_HUMAN" 2 1558.8104 33.91 35474 20558 2 1558.794872 780.4125 Striatin-4 OS=Homo sapiens OX=9606 GN=STRN4 PE=1 SV=2 4.53 3360.9 - 449431 - - - -9.9332 - 2.297 0.506 - 426.8 1 2 0 -0.0155 14 0 0 0 1.37E+08 4.03E+06 - - - 4.8603 0.9999 221125_WJC_METTL3_EV_vs_WT_F03.20560.20560.2 2.21E-10 16/36 R.APPSGSLGPVLPVVTSASK.L "sp|Q9Y5J3|HEY1_HUMAN,tr|A0A6I8PRS3|A0A6I8PRS3_HUMAN,tr|A0A6I8PRC2|A0A6I8PRC2_HUMAN,tr|B4DEI9|B4DEI9_HUMAN" 4 1762.9829 2.9 35476 20560 2 1762.981457 882.4987 Hairy\enhancer-of-split related with YRPW motif protein 1 OS=Homo sapiens OX=9606 GN=HEY1 PE=1 SV=1 8.8 3361.1 - 305622 - - - -0.8185 - 3.095 0.518 - 532.1 1 2 0 -0.0014 19 0 0 0 8.34E+06 2.88E+06 - - - 5.6441 1 221125_WJC_METTL3_EV_vs_WT_F03.20562.20562.3 1.13E-06 17/72 R.ILSAENIPNLPPGGGLAGK.R "sp|O75688|PPM1B_HUMAN,tr|B8ZZF0|B8ZZF0_HUMAN,tr|A0A3B3IS24|A0A3B3IS24_HUMAN,tr|C9JIR6|C9JIR6_HUMAN" 4 1817.0047 3.85 35477 20562 3 1817.006081 606.6755 Protein phosphatase 1B OS=Homo sapiens OX=9606 GN=PPM1B PE=1 SV=1 6 3361.4 - 1.23E+07 - - - 0.7606 - 2.824 0.555 - 267.9 1 2 0 0.0014 19 0 0 0 2.26E+08 5.87E+07 - - - 7.2779 1 221125_WJC_METTL3_EV_vs_WT_F03.20564.20564.3 0.000151 16/52 R.AVHEDIVAVELLPK.S "sp|Q9Y2L1|RRP44_HUMAN,tr|F2Z2C0|F2Z2C0_HUMAN,tr|G3V1J5|G3V1J5_HUMAN" 3 1531.861 2.14 35478 20564 3 1531.86195 511.6276 Exosome complex exonuclease RRP44 OS=Homo sapiens OX=9606 GN=DIS3 PE=1 SV=2 4.65 3361.6 - 5.35E+06 - - - 0.6241 - 2.718 0.515 - 395.5 1 2 0 0.001 14 0 0 0 1.90E+08 8.88E+07 - - - 6.9387 1 221125_WJC_METTL3_EV_vs_WT_F03.20567.20567.3 9.59E-13 14/52 K.C[160.03]EFQDAYVLLSEKK.L "sp|P10809|CH60_HUMAN,tr|A0A7I2V2X6|A0A7I2V2X6_HUMAN,tr|A0A7I2YQK6|A0A7I2YQK6_HUMAN,tr|A0A7I2V599|A0A7I2V599_HUMAN,tr|A0A7I2YQ71|A0A7I2YQ71_HUMAN,tr|A0A7I2V5M1|A0A7I2V5M1_HUMAN,tr|A0A7I2V5K3|A0A7I2V5K3_HUMAN,tr|A0A7I2V369|A0A7I2V369_HUMAN" 8 1728.8393 1.16 35481 20567 3 1728.837695 577.287 "60 kDa heat shock protein, mitochondrial OS=Homo sapiens OX=9606 GN=HSPD1 PE=1 SV=2" 4.68 3361.7 - 2.85E+06 - - - -0.9128 - 2.605 0.657 - 245 1 2 0 -0.0016 14 0 0 0 1.00E+09 8.59E+08 - - - 8.4089 0.9999 221125_WJC_METTL3_EV_vs_WT_F03.20568.20568.3 0.000102 16/64 R.LSASSSISSADLFEEPR.K "sp|Q9NP61|ARFG3_HUMAN,tr|H0Y6A0|H0Y6A0_HUMAN" 2 1794.8636 1.63 35482 20568 3 1794.866645 599.2951 ADP-ribosylation factor GTPase-activating protein 3 OS=Homo sapiens OX=9606 GN=ARFGAP3 PE=1 SV=1 4.14 3361.8 - 2.01E+06 - - - 1.7116 - 2.895 0.448 - 360.5 1 2 0 0.0031 17 0 0 0 4.27E+07 2.63E+07 - - - 6.2193 0.9999 221125_WJC_METTL3_EV_vs_WT_F03.20569.20569.2 5.19E-06 14/22 R.STDYGIFQINSR.Y "sp|P61626|LYSC_HUMAN,tr|A0A0B4J259|A0A0B4J259_HUMAN,tr|F8VV32|F8VV32_HUMAN" 3 1399.6732 1521.81 35483 20569 2 1399.674205 700.8439 Lysozyme C OS=Homo sapiens OX=9606 GN=LYZ PE=1 SV=1 5.55 3361.9 - 1.47E+06 - - - 0.723 - 2.75 0.541 - 825.6 1 2 0 0.001 12 0 0 0 2.71E+08 1.78E+05 - - - 5.6982 1 221125_WJC_METTL3_EV_vs_WT_F03.20570.20570.3 1.01E-06 14/48 R.GNPTVEVDLFTSK.G "sp|P06733|ENOA_HUMAN,tr|A0A2R8Y6G6|A0A2R8Y6G6_HUMAN,tr|A0A2R8YEG5|A0A2R8YEG5_HUMAN,tr|K7ERS8|K7ERS8_HUMAN,tr|K7EM90|K7EM90_HUMAN,tr|A0A2R8Y879|A0A2R8Y879_HUMAN,tr|A0A2R8Y798|A0A2R8Y798_HUMAN,tr|A0A2R8YEM5|A0A2R8YEM5_HUMAN" 8 1405.7089 1.77 35484 20570 3 1405.707705 469.5769 Alpha-enolase OS=Homo sapiens OX=9606 GN=ENO1 PE=1 SV=2 4.37 3362 - 1.36E+06 - - - -0.8572 - 2.663 0.509 - 344.3 1 2 0 -0.0012 13 0 0 0 3.72E+07 2.10E+07 - - - 6.8701 1 221125_WJC_METTL3_EV_vs_WT_F03.20574.20574.3 1.76E-09 15/52 R.GHVLPLALQMYGC[160.03]R[166.11].V "sp|Q8TB72|PUM2_HUMAN,tr|A0A0C4DG68|A0A0C4DG68_HUMAN" 2 1623.8253 1.15 35488 20574 3 1623.826152 542.2824 Pumilio homolog 2 OS=Homo sapiens OX=9606 GN=PUM2 PE=1 SV=2 8.23 3362.4 - 953582 - - - 0.5198 - 2.862 0.452 - 281.8 1 2 0 0.0008 14 0 0 0 1.94E+07 1.68E+07 - - - 6.3736 0.8633 221125_WJC_METTL3_EV_vs_WT_F03.20576.20576.2 0.00167 24-Dec R.YLNIFGESQPNPK[136.11].T "sp|Q9UJS0|CMC2_HUMAN,tr|R4GN64|R4GN64_HUMAN" 2 1513.7656 0.93 35490 20576 2 1514.77677 757.8901 Calcium-binding mitochondrial carrier protein Aralar2 OS=Homo sapiens OX=9606 GN=SLC25A13 PE=1 SV=2 6 3362.7 - 1.52E+06 - - - 667.9541 - 2.392 0.445 - 512.4 1 2 0 1.0111 13 0 0 0 1.91E+07 2.05E+07 - - - 4.2486 0.9999 221125_WJC_METTL3_EV_vs_WT_F03.20577.20577.3 0.000139 Dec-40 R.LGLHQVLQDLR[166.11].E "sp|O60610|DIAP1_HUMAN,tr|A0A2R8Y5N1|A0A2R8Y5N1_HUMAN,tr|A0A140T8Z0|A0A140T8Z0_HUMAN,tr|A0A0G2JH68|A0A0G2JH68_HUMAN,tr|H9KV28|H9KV28_HUMAN" 5 1300.7491 0.93 35491 20577 3 1300.748359 434.5903 Protein diaphanous homolog 1 OS=Homo sapiens OX=9606 GN=DIAPH1 PE=1 SV=2 6.74 3362.8 - 798362 - - - -0.562 - 2.6 0.413 - 199.7 1 2 0 -0.0007 11 0 0 0 6.29E+06 6.75E+06 - - - 5.8588 1 221125_WJC_METTL3_EV_vs_WT_F03.20579.20579.2 1.26E-10 13/36 K.ILATPPQEDAPSVDIANIR.M "sp|P29401|TKT_HUMAN,tr|E9PFF2|E9PFF2_HUMAN,tr|A0A0B4J1R6|A0A0B4J1R6_HUMAN" 3 2019.0637 0.79 35493 20579 2 2019.065182 1010.5391 Transketolase OS=Homo sapiens OX=9606 GN=TKT PE=1 SV=3 4.03 3363.1 - 336626 - - - 0.7489 - 2.796 0.637 - 203 1 2 0 0.0015 19 0 0 0 4.32E+06 5.49E+06 - - - 6.2733 1 221125_WJC_METTL3_EV_vs_WT_F03.20580.20580.2 4.88E-09 14/32 K.MGGMEGPFGGGMENMGR[166.11].F "sp|P52272|HNRPM_HUMAN,tr|M0QYL3|M0QYL3_HUMAN,tr|A0A087X0X3|A0A087X0X3_HUMAN,tr|M0QZM1|M0QZM1_HUMAN" 4 1723.6814 1.64 35494 20580 2 1723.682389 862.848 Heterogeneous nuclear ribonucleoprotein M OS=Homo sapiens OX=9606 GN=HNRNPM PE=1 SV=3 4.53 3363.2 - 328394 - - - 0.561 - 2.745 0.752 - 581 1 2 0 0.001 17 0 0 0 1.79E+07 1.09E+07 - - - 7.0776 0.9996 221125_WJC_METTL3_EV_vs_WT_F03.20583.20583.2 0.000464 16-Aug R.DVTTFFSGK[136.11].A "sp|Q8N6T3|ARFG1_HUMAN,tr|F8VWH9|F8VWH9_HUMAN,tr|F8W1U7|F8W1U7_HUMAN,tr|E5RHH7|E5RHH7_HUMAN" 4 1008.5008 1.33 35495 20583 2 1008.500785 505.2577 ADP-ribosylation factor GTPase-activating protein 1 OS=Homo sapiens OX=9606 GN=ARFGAP1 PE=1 SV=2 5.84 3363.6 - 3.86E+06 - - - 0.0228 - 1.465 0.407 - 157.2 1 2 0 0 9 0 0 0 5.44E+07 4.10E+07 - - - 3.1518 0.9998 221125_WJC_METTL3_EV_vs_WT_F03.20584.20584.2 0.000135 18-Nov K.VDSLLENLEK[136.11].L "sp|P0DMR1|HNRC4_HUMAN,sp|P07910|HNRPC_HUMAN,sp|O60812|HNRC1_HUMAN,sp|B2RXH8|HNRC2_HUMAN,sp|B7ZW38|HNRC3_HUMAN,tr|B4DY08|B4DY08_HUMAN,tr|G3V5V7|G3V5V7_HUMAN,tr|B2R5W2|B2R5W2_HUMAN,tr|G3V4C1|G3V4C1_HUMAN,tr|A0A0G2JPF8|A0A0G2JPF8_HUMAN,tr|A0A0G2JNQ3|A0A0G2JNQ3_HUMAN,tr|G3V576|G3V576_HUMAN,tr|G3V2D6|G3V2D6_HUMAN,tr|G3V4W0|G3V4W0_HUMAN,tr|G3V2Q1|G3V2Q1_HUMAN" 15 1166.6274 1.54 35496 20584 2 1166.628423 584.321 Heterogeneous nuclear ribonucleoprotein C-like 4 OS=Homo sapiens OX=9606 GN=HNRNPCL4 PE=3 SV=1 4.14 3363.7 - 3.34E+06 - - - 0.8606 - 2.258 0.432 - 462.9 1 2 0 0.001 10 0 0 0 7.01E+07 4.55E+07 - - - 4.5049 1 221125_WJC_METTL3_EV_vs_WT_F03.20585.20585.2 2.85E-10 22/36 R.ILSAENIPNLPPGGGLAGK[136.11].R "sp|O75688|PPM1B_HUMAN,tr|B8ZZF0|B8ZZF0_HUMAN,tr|A0A3B3IS24|A0A3B3IS24_HUMAN,tr|C9JIR6|C9JIR6_HUMAN" 4 1825.0189 3.71 35497 20585 2 1825.016827 913.5167 Protein phosphatase 1B OS=Homo sapiens OX=9606 GN=PPM1B PE=1 SV=1 6 3363.8 - 2.15E+06 - - - -1.1353 - 3.333 0.509 - 790.8 1 2 0 -0.0021 19 0 0 0 1.77E+08 4.78E+07 - - - 5.7596 1 221125_WJC_METTL3_EV_vs_WT_F03.20587.20587.2 2.58E-07 16/28 R.DASLMVTNDGATILK.N "sp|P78371|TCPB_HUMAN,tr|F8VQ14|F8VQ14_HUMAN,tr|F5GWF6|F5GWF6_HUMAN" 3 1547.7865 0.42 35499 20587 2 1547.791753 774.9005 T-complex protein 1 subunit beta OS=Homo sapiens OX=9606 GN=CCT2 PE=1 SV=4 4.21 3363.9 - 1.76E+06 - - - 3.3881 - 2.738 0.57 - 730.8 1 2 0 0.0052 15 0 0 0 2.88E+08 6.89E+08 - - - 5.7257 1 221125_WJC_METTL3_EV_vs_WT_F03.20588.20588.3 2.24E-09 16/88 R.IIMTSSASGIYGNFGQANYSAAK[136.11].L "sp|P51659|DHB4_HUMAN,tr|A0A2R8YD50|A0A2R8YD50_HUMAN,tr|E7ET17|E7ET17_HUMAN,tr|E7ER27|E7ER27_HUMAN,tr|E7EPL9|E7EPL9_HUMAN,tr|A0A804HKU2|A0A804HKU2_HUMAN,tr|A0A804HIG8|A0A804HIG8_HUMAN,tr|A0A2R8Y7W2|A0A2R8Y7W2_HUMAN,tr|A0A2R8YDT8|A0A2R8YDT8_HUMAN,tr|A0A804HK65|A0A804HK65_HUMAN" 10 2358.1405 0.04 35500 20588 3 2358.142304 787.0541 Peroxisomal multifunctional enzyme type 2 OS=Homo sapiens OX=9606 GN=HSD17B4 PE=1 SV=3 8.5 3364.1 - 991254 - - - 0.7451 - 2.867 0.609 - 147.2 1 2 0 0.0018 23 0 0 0 4.60E+05 1.17E+07 - - - 7.8002 0.9986 221125_WJC_METTL3_EV_vs_WT_F03.20589.20589.3 5.32E-09 16/64 A.VDYYTTTPALVFGKPVR.V "sp|P43243|MATR3_HUMAN,tr|B3KM87|B3KM87_HUMAN,tr|A8MXP9|A8MXP9_HUMAN,tr|D6RBK5|D6RBK5_HUMAN,tr|A0A0R4J2E8|A0A0R4J2E8_HUMAN,tr|H0Y8T4|H0Y8T4_HUMAN,tr|D6REM6|D6REM6_HUMAN" 7 1926.0251 0.74 35501 20589 3 1926.026075 643.0156 Matrin-3 OS=Homo sapiens OX=9606 GN=MATR3 PE=1 SV=2 8.47 3364.1 - 797274 - - - 0.5062 - 3.069 0.564 - 204.4 1 1 0 0.001 17 0 0 0 1.17E+07 1.58E+07 - - - 7.6606 1 221125_WJC_METTL3_EV_vs_WT_F03.20592.20592.2 3.27E-10 13/34 K.SSPEVSSINQEALVLTAK.A "sp|Q9NRG0|CHRC1_HUMAN,tr|E5RGS9|E5RGS9_HUMAN" 2 1871.984 1.65 35504 20592 2 1871.987933 936.9993 Chromatin accessibility complex protein 1 OS=Homo sapiens OX=9606 GN=CHRAC1 PE=1 SV=1 4.53 3364.5 - 432451 - - - 2.0887 - 2.86 0.623 - 362 1 2 0 0.0039 18 0 0 0 1.34E+07 8.12E+06 - - - 6.2247 1 221125_WJC_METTL3_EV_vs_WT_F03.20593.20593.2 5.28E-09 14/28 K.ELNMPFSGGQDSFSK.F "sp|Q5VT06|CE350_HUMAN,tr|H0Y6Q4|H0Y6Q4_HUMAN" 2 1642.7297 1.46 35505 20593 2 1642.734261 822.3721 Centrosome-associated protein 350 OS=Homo sapiens OX=9606 GN=CEP350 PE=1 SV=1 4.37 3364.7 - 319667 - - - 2.7631 - 2.642 0.602 - 515.2 1 2 0 0.0045 15 0 0 0 5.44E+06 3.72E+06 - - - 5.8745 0.9999 221125_WJC_METTL3_EV_vs_WT_F03.20597.20597.2 1.44E-05 Dec-32 R.FSPNSSNPIIVSC[160.03]GWDK.L "sp|P63244|RACK1_HUMAN,tr|H0YAM7|H0YAM7_HUMAN,tr|D6RFX4|D6RFX4_HUMAN,tr|H0YAF8|H0YAF8_HUMAN,tr|D6R9Z1|D6R9Z1_HUMAN,tr|J3KPE3|J3KPE3_HUMAN,tr|D6R9L0|D6R9L0_HUMAN,tr|D6RHH4|D6RHH4_HUMAN,tr|D6RBD0|D6RBD0_HUMAN,tr|D6RAC2|D6RAC2_HUMAN,tr|H0Y8R5|H0Y8R5_HUMAN,tr|D6REE5|D6REE5_HUMAN,tr|H0Y8W2|H0Y8W2_HUMAN" 13 1906.8883 1.31 35508 20597 2 1906.890321 954.4515 Receptor of activated protein C kinase 1 OS=Homo sapiens OX=9606 GN=RACK1 PE=1 SV=3 5.83 3365.1 - 1.66E+06 - - - 1.0347 - 2.504 0.514 - 366 1 2 0 0.002 17 0 0 0 2.38E+07 1.82E+07 - - - 5.0935 1 221125_WJC_METTL3_EV_vs_WT_F03.20598.20598.3 9.14E-08 15/52 R.AVHEDIVAVELLPK[136.11].S "sp|Q9Y2L1|RRP44_HUMAN,tr|F2Z2C0|F2Z2C0_HUMAN,tr|G3V1J5|G3V1J5_HUMAN" 3 1539.8752 2.19 35509 20598 3 1539.876523 514.299 Exosome complex exonuclease RRP44 OS=Homo sapiens OX=9606 GN=DIS3 PE=1 SV=2 4.65 3365.2 - 5.32E+06 - - - 0.8631 - 3.01 0.513 - 347.6 1 2 0 0.0013 14 0 0 0 1.86E+08 8.48E+07 - - - 7.1875 0.9998 221125_WJC_METTL3_EV_vs_WT_F03.20599.20599.2 4.67E-07 24-Oct R.QEPSDSPMFIINR.N sp|Q02413|DSG1_HUMAN 1 1532.7293 999 35510 20599 2 1532.726472 767.3719 Desmoglein-1 OS=Homo sapiens OX=9606 GN=DSG1 PE=1 SV=2 4.37 3365.2 - 3.71E+06 - - - -1.8633 - 2.264 0.566 - 359.3 1 2 0 -0.0029 13 0 0 0 7.55E+07 0.00E+00 - - - 5.3178 0.9999 221125_WJC_METTL3_EV_vs_WT_F03.20600.20600.3 8.58E-07 17/72 R.FVASK[136.11]PLEEEEMEVPVLPK[136.11].L sp|P49790|NU153_HUMAN 1 2186.1516 1.59 35511 20600 3 2186.15772 729.7245 Nuclear pore complex protein Nup153 OS=Homo sapiens OX=9606 GN=NUP153 PE=1 SV=2 4.33 3365.3 - 1.81E+06 - - - 2.8182 - 2.605 0.464 - 218.7 1 2 0 0.0062 19 0 0 0 9.21E+07 5.79E+07 - - - 6.0637 0.9998 221125_WJC_METTL3_EV_vs_WT_F03.20601.20601.2 0.205 15/26 K.FQSIVIGC[160.03]ALEDQK[136.11].K sp|O95816|BAG2_HUMAN 1 1614.8167 0.12 35512 20601 2 1614.814607 808.4156 BAG family molecular chaperone regulator 2 OS=Homo sapiens OX=9606 GN=BAG2 PE=1 SV=1 4.37 3365.4 - 1.29E+06 - - - -1.2918 - 2.34 0.412 - 645 1 2 0 -0.0021 14 0 0 0 2.12E+06 1.81E+07 - - - 4.2168 1 221125_WJC_METTL3_EV_vs_WT_F03.20602.20602.3 1.35E-06 15/52 K.LTLDTIFVPNTGK[136.11]K[136.11].S "sp|Q9Y277|VDAC3_HUMAN,tr|E5RJN6|E5RJN6_HUMAN,tr|E5RK27|E5RK27_HUMAN,tr|E5RFP6|E5RFP6_HUMAN,tr|E5RHZ6|E5RHZ6_HUMAN" 5 1561.905 2.58 35513 20602 3 1561.905924 521.6423 Voltage-dependent anion-selective channel protein 3 OS=Homo sapiens OX=9606 GN=VDAC3 PE=1 SV=1 8.59 3365.5 - 1.25E+06 - - - 0.5634 - 2.887 0.526 - 258.5 1 2 0 0.0009 14 0 0 0 3.12E+07 1.21E+07 - - - 7.2217 1 221125_WJC_METTL3_EV_vs_WT_F03.20607.20607.3 2.85E-08 17/72 R.FVASKPLEEEEMEVPVLPK.L sp|P49790|NU153_HUMAN 1 2170.1232 1.59 35516 20607 3 2170.125561 724.3817 Nuclear pore complex protein Nup153 OS=Homo sapiens OX=9606 GN=NUP153 PE=1 SV=2 4.33 3366.1 - 3.67E+06 - - - 1.1068 - 3.119 0.521 - 175.7 1 2 0 0.0024 19 0 0 0 9.21E+07 5.79E+07 - - - 7.1426 1 221125_WJC_METTL3_EV_vs_WT_F03.20608.20608.3 9.58E-12 21/72 K.ILATPPQEDAPSVDIANIR.M "sp|P29401|TKT_HUMAN,tr|E9PFF2|E9PFF2_HUMAN,tr|A0A0B4J1R6|A0A0B4J1R6_HUMAN" 3 2019.0637 0.45 35517 20608 3 2019.067909 674.0285 Transketolase OS=Homo sapiens OX=9606 GN=TKT PE=1 SV=3 4.03 3366.2 - 1.39E+06 - - - 2.0995 - 3.859 0.62 - 568.1 1 2 0 0.0042 19 0 0 0 2.38E+07 5.30E+07 - - - 8.7689 0.9999 221125_WJC_METTL3_EV_vs_WT_F03.20609.20609.3 0.000114 Nov-44 R.STDYGIFQINSR.Y "sp|P61626|LYSC_HUMAN,tr|A0A0B4J259|A0A0B4J259_HUMAN,tr|F8VV32|F8VV32_HUMAN" 3 1399.6732 999 35518 20609 3 1399.672331 467.565 Lysozyme C OS=Homo sapiens OX=9606 GN=LYZ PE=1 SV=1 5.55 3366.3 - 1.67E+06 - - - -0.6159 - 2.136 0.401 - 123.7 1 2 0 -0.0009 12 0 0 0 2.25E+07 0.00E+00 - - - 5.1142 1 221125_WJC_METTL3_EV_vs_WT_F03.20610.20610.3 8.64E-09 24/84 R.IIANALSSEPAC[160.03]LAEIEEDKAR.R sp|P78527|PRKDC_HUMAN 1 2399.2002 1.03 35519 20610 3 2399.201201 800.7407 DNA-dependent protein kinase catalytic subunit OS=Homo sapiens OX=9606 GN=PRKDC PE=1 SV=3 4.25 3366.4 - 1.25E+06 - - - 0.4006 - 4.122 0.636 - 721 1 2 1 0.001 22 0 0 0 1.38E+07 1.35E+07 - - - 8.9884 0.9997 221125_WJC_METTL3_EV_vs_WT_F03.20611.20611.2 1.96E-05 24-Oct R.YLNIFGESQPNPK[136.11].T "sp|Q9UJS0|CMC2_HUMAN,tr|R4GN64|R4GN64_HUMAN" 2 1513.7656 0.79 35520 20611 2 1513.768705 757.8901 Calcium-binding mitochondrial carrier protein Aralar2 OS=Homo sapiens OX=9606 GN=SLC25A13 PE=1 SV=2 6 3366.5 - 1.01E+06 - - - 2.0221 - 2.242 0.467 - 255.4 1 2 0 0.0031 13 0 0 0 1.62E+07 2.05E+07 - - - 4.5614 0.9998 221125_WJC_METTL3_EV_vs_WT_F03.20612.20612.3 0.000789 Aug-32 R.EHLELFWSR[166.11].V "sp|Q00610|CLH1_HUMAN,sp|P53675|CLH2_HUMAN,tr|J3KS13|J3KS13_HUMAN,tr|A0A087WV74|A0A087WV74_HUMAN,tr|A0A087WXH4|A0A087WXH4_HUMAN,tr|A0A087WVQ6|A0A087WVQ6_HUMAN" 6 1225.6119 0.92 35521 20612 3 1225.611321 409.5446 Clathrin heavy chain 1 OS=Homo sapiens OX=9606 GN=CLTC PE=1 SV=5 5.4 3366.6 - 930959 - - - -0.4944 - 1.671 0.398 - 104.5 1 2 0 -0.0006 9 0 0 0 9.45E+06 1.03E+07 - - - 4.5245 0.9993 221125_WJC_METTL3_EV_vs_WT_F03.20613.20613.2 0.000122 28-Nov R.ALTVPELTQQMFDSK.N "sp|Q9BVA1|TBB2B_HUMAN,sp|Q13885|TBB2A_HUMAN" 2 1706.8549 1 35522 20613 2 1706.859618 854.4347 Tubulin beta-2B chain OS=Homo sapiens OX=9606 GN=TUBB2B PE=1 SV=1 4.37 3366.7 - 834118 - - - 2.7507 - 1.847 0.488 - 225.3 1 2 0 0.0047 15 0 0 0 2.77E+07 2.76E+07 - - - 4.1524 0.9976 221125_WJC_METTL3_EV_vs_WT_F03.20614.20614.2 0.0545 26-Aug K.SLPVPGALEQVASR[166.11].L "tr|A0A669KBG4|A0A669KBG4_HUMAN,tr|A0A669KAV7|A0A669KAV7_HUMAN,tr|M0QXA7|M0QXA7_HUMAN,tr|A0A669KBH9|A0A669KBH9_HUMAN,tr|B9EGQ5|B9EGQ5_HUMAN" 5 1432.7913 0.54 35523 20614 2 1432.789544 717.403 Protein Wiz OS=Homo sapiens OX=9606 GN=WIZ PE=1 SV=1 5.72 3366.9 - 435806 - - - -1.2591 - 1.497 0.285 - 117.5 4 2 0 -0.0018 14 0 0 0 1.85E+06 3.40E+06 - - - 1.889 1 221125_WJC_METTL3_EV_vs_WT_F03.20616.20616.3 6.50E-07 Nov-64 R.LSASSSISSADLFEEPR[166.11].K "sp|Q9NP61|ARFG3_HUMAN,tr|H0Y6A0|H0Y6A0_HUMAN" 2 1804.8718 1.65 35524 20616 3 1804.870967 602.6312 ADP-ribosylation factor GTPase-activating protein 3 OS=Homo sapiens OX=9606 GN=ARFGAP3 PE=1 SV=1 4.14 3367.1 - 1.75E+06 - - - -0.4854 - 2.224 0.503 - 152.8 1 2 0 -0.0009 17 0 0 0 4.27E+07 2.60E+07 - - - 6.167 1 221125_WJC_METTL3_EV_vs_WT_F03.20618.20618.3 0.000191 16/60 K.KPELVISYLPPGMASK.L "sp|P78347|GTF2I_HUMAN,tr|A0A494C1K3|A0A494C1K3_HUMAN" 2 1728.9484 1.61 35525 20618 3 1728.949636 577.3234 General transcription factor II-I OS=Homo sapiens OX=9606 GN=GTF2I PE=1 SV=2 8.5 3367.3 - 3.07E+06 - - - 0.6981 - 2.573 0.532 - 301.4 1 2 0 0.0012 16 0 0 0 1.19E+08 7.38E+07 - - - 6.8959 1 221125_WJC_METTL3_EV_vs_WT_F03.20619.20619.3 2.24E-08 14/56 R.DASLMVTNDGATILK[136.11].N "sp|P78371|TCPB_HUMAN,tr|F8VQ14|F8VQ14_HUMAN,tr|F5GWF6|F5GWF6_HUMAN" 3 1555.8007 0.77 35526 20619 3 1555.80168 519.6075 T-complex protein 1 subunit beta OS=Homo sapiens OX=9606 GN=CCT2 PE=1 SV=4 4.21 3367.3 - 2.50E+06 - - - 0.6241 - 2.926 0.649 - 276.8 1 2 0 0.001 15 0 0 0 3.18E+07 4.15E+07 - - - 8.5769 1 221125_WJC_METTL3_EV_vs_WT_F03.20620.20620.3 3.48E-07 14/48 R.EEVPLELVEAHVK.K sp|Q92922|SMRC1_HUMAN 1 1490.7981 999 35527 20620 3 1490.799653 497.94 SWI\SNF complex subunit SMARCC1 OS=Homo sapiens OX=9606 GN=SMARCC1 PE=1 SV=3 4.48 3367.4 - 2.58E+06 - - - 1.0686 - 2.333 0.541 - 290.7 1 2 0 0.0016 13 0 0 0 2.46E+07 0.00E+00 - - - 6.8681 1 221125_WJC_METTL3_EV_vs_WT_F03.20621.20621.3 4.57E-07 19/60 K.K[136.11]PELVISYLPPGMASK[136.11].L "sp|P78347|GTF2I_HUMAN,tr|A0A494C1K3|A0A494C1K3_HUMAN" 2 1744.9768 1.61 35528 20621 3 1744.977238 582.6662 General transcription factor II-I OS=Homo sapiens OX=9606 GN=GTF2I PE=1 SV=2 8.5 3367.5 - 2.24E+06 - - - 0.2344 - 3.511 0.52 - 458.2 1 2 0 0.0004 16 0 0 0 1.19E+08 7.38E+07 - - - 7.5598 0.997 221125_WJC_METTL3_EV_vs_WT_F03.20622.20622.3 2.85E-07 17/76 R.LGQHVPTLHPTSEELTIAGM.T "sp|Q9NR31|SAR1A_HUMAN,sp|Q9Y6B6|SAR1B_HUMAN,tr|D6RAA2|D6RAA2_HUMAN,tr|D6RD69|D6RD69_HUMAN,tr|Q5SQT8|Q5SQT8_HUMAN,tr|D6RDB2|D6RDB2_HUMAN" 6 2130.0779 - 35529 20622 3 2130.07825 711.0333 GTP-binding protein SAR1a OS=Homo sapiens OX=9606 GN=SAR1A PE=1 SV=1 5.23 3367.6 - 2.22E+06 - - - 0.1455 - 2.706 0.504 - 338.2 1 1 0 0.0003 20 0 0 0 - - - - - 6.5741 1 221125_WJC_METTL3_EV_vs_WT_F03.20623.20623.2 0.000343 14/28 K.QDLPNAMAISEMTDK.L "sp|P18085|ARF4_HUMAN,tr|C9JAK5|C9JAK5_HUMAN,tr|U3KQF2|U3KQF2_HUMAN" 3 1662.7593 0.87 35530 20623 2 1662.75922 832.3869 ADP-ribosylation factor 4 OS=Homo sapiens OX=9606 GN=ARF4 PE=1 SV=3 4.03 3367.7 - 1.26E+06 - - - -0.0529 - 3.069 0.595 - 589.8 1 2 0 -0.0001 15 0 0 0 1.75E+07 2.02E+07 - - - 6.1925 1 221125_WJC_METTL3_EV_vs_WT_F03.20624.20624.3 2.44E-09 16/60 K.IEWLESHQDADIEDFK[136.11].A "sp|P11021|BIP_HUMAN,tr|A0A7P0TB36|A0A7P0TB36_HUMAN,tr|A0A7P0TAI0|A0A7P0TAI0_HUMAN" 3 1981.9149 0.57 35531 20624 3 1981.912142 661.6456 Endoplasmic reticulum chaperone BiP OS=Homo sapiens OX=9606 GN=HSPA5 PE=1 SV=2 4.01 3367.8 - 752697 - - - -1.385 - 3.74 0.527 - 258.3 1 2 0 -0.0027 16 0 0 0 6.98E+07 1.22E+08 - - - 7.7994 1 221125_WJC_METTL3_EV_vs_WT_F03.20625.20625.3 1.26E-06 16/44 K.GFDILGIK[136.11]PVQR[166.11].M sp|P54136|SYRC_HUMAN 1 1359.7993 1.01 35532 20625 3 1359.800104 454.2737 "Arginine--tRNA ligase, cytoplasmic OS=Homo sapiens OX=9606 GN=RARS1 PE=1 SV=2" 8.75 3367.9 - 707372 - - - 0.5611 - 2.702 0.515 - 320.5 1 2 0 0.0008 12 0 0 0 1.30E+07 1.29E+07 - - - 7.0367 0.9998 221125_WJC_METTL3_EV_vs_WT_F03.20626.20626.3 0.0057 13/44 K.VLFEQAFSFHGK[136.11].T "sp|Q9UKL0|RCOR1_HUMAN,sp|Q9P2K3|RCOR3_HUMAN,tr|B4DV59|B4DV59_HUMAN,tr|E9PQE5|E9PQE5_HUMAN" 4 1416.7281 1.81 35533 20626 3 1416.72721 473.25 REST corepressor 1 OS=Homo sapiens OX=9606 GN=RCOR1 PE=1 SV=2 6.72 3368.1 - 614645 - - - -0.6536 - 2.37 0.344 - 164.3 1 2 0 -0.0009 12 0 0 0 2.63E+07 1.45E+07 - - - 4.7668 1 221125_WJC_METTL3_EV_vs_WT_F03.20627.20627.2 7.80E-09 16/34 K.SSPEVSSINQEALVLTAK[136.11].A "sp|Q9NRG0|CHRC1_HUMAN,tr|E5RGS9|E5RGS9_HUMAN" 2 1879.9982 1.65 35534 20627 2 1879.997995 941.0064 Chromatin accessibility complex protein 1 OS=Homo sapiens OX=9606 GN=CHRAC1 PE=1 SV=1 4.53 3368.2 - 604484 - - - -0.1213 - 3.041 0.637 - 553.3 1 2 0 -0.0002 18 0 0 0 1.34E+07 8.12E+06 - - - 6.4802 0.7772 221125_WJC_METTL3_EV_vs_WT_F03.20628.20628.2 2.07E-06 Sep-32 K.FDTGNLC[160.03]MVTGGANLGR.L sp|P62701|RS4X_HUMAN 1 1781.8189 -1 35535 20628 2 1782.810272 891.9167 "40S ribosomal protein S4, X isoform OS=Homo sapiens OX=9606 GN=RPS4X PE=1 SV=2" 5.83 3368.3 - 386357 - - - 556.3882 - 2.125 0.601 - 171.9 1 2 0 0.9914 17 0 0 0 0.00E+00 0.00E+00 - - - 5.0219 0.9999 221125_WJC_METTL3_EV_vs_WT_F03.20630.20630.2 3.75E-06 Sep-36 K.ILATPPQEDAPSVDIANIR[166.11].M "sp|P29401|TKT_HUMAN,tr|E9PFF2|E9PFF2_HUMAN,tr|A0A0B4J1R6|A0A0B4J1R6_HUMAN" 3 2029.0719 0.79 35537 20630 2 2029.073421 1015.5432 Transketolase OS=Homo sapiens OX=9606 GN=TKT PE=1 SV=3 4.03 3368.6 - 265331 - - - 0.7299 - 2.126 0.528 - 109.9 1 2 0 0.0015 19 0 0 0 4.32E+06 5.49E+06 - - - 4.7947 0.9994 221125_WJC_METTL3_EV_vs_WT_F03.20633.20633.3 0.0463 Dec-48 K.MFIGGLSWDTTK[136.11]K[136.11].D "sp|Q14103|HNRPD_HUMAN,tr|H0Y8G5|H0Y8G5_HUMAN,tr|D6RF44|D6RF44_HUMAN,tr|D6RD83|D6RD83_HUMAN,tr|D6RBQ9|D6RBQ9_HUMAN,tr|D6RAF8|D6RAF8_HUMAN,tr|H0YA96|H0YA96_HUMAN" 7 1498.7825 1.73 35538 20633 3 1498.777543 500.6014 Heterogeneous nuclear ribonucleoprotein D0 OS=Homo sapiens OX=9606 GN=HNRNPD PE=1 SV=1 8.35 3369 - 4.36E+06 - - - -3.298 - 2.41 0.362 - 183.6 1 2 0 -0.0049 13 0 0 0 1.97E+08 1.14E+08 - - - 4.9595 0.9973 221125_WJC_METTL3_EV_vs_WT_F03.20635.20635.2 0.88 20-Jul K.MDLESQIESLK.E sp|Q13515|BFSP2_HUMAN 1 1291.633 3.13 35540 20635 2 1291.632984 646.8238 Phakinin OS=Homo sapiens OX=9606 GN=BFSP2 PE=1 SV=1 4.14 3369.1 - 2.92E+06 - - - 0.0124 - 1.566 0.175 - 237.3 1 2 0 0 11 0 0 0 2.83E+07 9.05E+06 - - - 1.5469 1 221125_WJC_METTL3_EV_vs_WT_F03.20636.20636.3 6.28E-07 16/60 K.IEWLESHQDADIEDFK.A "sp|P11021|BIP_HUMAN,tr|A0A7P0TB36|A0A7P0TB36_HUMAN,tr|A0A7P0TAI0|A0A7P0TAI0_HUMAN" 3 1973.9007 0.57 35541 20636 3 1973.896861 658.9742 Endoplasmic reticulum chaperone BiP OS=Homo sapiens OX=9606 GN=HSPA5 PE=1 SV=2 4.01 3369.2 - 2.19E+06 - - - -1.9383 - 3.394 0.621 - 333.9 1 2 0 -0.0038 16 0 0 0 6.98E+07 1.22E+08 - - - 8.598 0.9933 221125_WJC_METTL3_EV_vs_WT_F03.20638.20638.2 0.00407 15/22 D.NANILLQIDNAR.L "sp|Q04695|K1C17_HUMAN,sp|P13645|K1C10_HUMAN,tr|K7EPJ9|K7EPJ9_HUMAN,tr|A0A1B0GVI3|A0A1B0GVI3_HUMAN,tr|F5GWP8|F5GWP8_HUMAN" 5 1353.7365 999 35543 20638 2 1353.737273 677.8755 "Keratin, type I cytoskeletal 17 OS=Homo sapiens OX=9606 GN=KRT17 PE=1 SV=2" 5.84 3369.3 - 1.33E+06 - - - 0.5991 - 2.862 0.464 - 847.5 1 1 0 0.0008 12 0 0 0 1.62E+07 0.00E+00 - - - 5.2346 1 221125_WJC_METTL3_EV_vs_WT_F03.20639.20639.3 1.39E-05 26/64 R.YPNIELSYEVVDKDSIR.S sp|O75643|U520_HUMAN 1 2039.0211 2.42 35544 20639 3 2039.022753 680.681 U5 small nuclear ribonucleoprotein 200 kDa helicase OS=Homo sapiens OX=9606 GN=SNRNP200 PE=1 SV=2 4.32 3369.4 - 1.15E+06 - - - 0.7925 - 4.773 0.603 - 1184.5 1 2 1 0.0016 17 0 0 0 2.39E+07 9.89E+06 - - - 9.211 0.9975 221125_WJC_METTL3_EV_vs_WT_F03.20644.20644.3 0.375 Dec-40 K.SIIETMEQHLK.Q "sp|Q6N021|TET2_HUMAN,tr|E7EQS8|E7EQS8_HUMAN,tr|E7EPB1|E7EPB1_HUMAN" 3 1327.6806 0.96 35549 20644 3 1327.680519 443.5675 Methylcytosine dioxygenase TET2 OS=Homo sapiens OX=9606 GN=TET2 PE=1 SV=3 5.38 3370 - 677366 - - - -0.0512 - 1.837 0.217 - 126.2 1 2 0 -0.0001 11 0 0 0 5.19E+06 5.39E+06 - - - 2.6869 1 221125_WJC_METTL3_EV_vs_WT_F03.20646.20646.2 1.24E-09 16/26 R.AVHEDIVAVELLPK[136.11].S "sp|Q9Y2L1|RRP44_HUMAN,tr|F2Z2C0|F2Z2C0_HUMAN,tr|G3V1J5|G3V1J5_HUMAN" 3 1539.8752 2.5 35551 20646 2 1539.87358 770.9449 Exosome complex exonuclease RRP44 OS=Homo sapiens OX=9606 GN=DIS3 PE=1 SV=2 4.65 3370.3 - 568962 - - - -1.0481 - 2.891 0.633 - 643.3 1 2 0 -0.0016 14 0 0 0 1.83E+07 7.33E+06 - - - 6.3799 0.9999 221125_WJC_METTL3_EV_vs_WT_F03.20647.20647.3 1.29E-05 Sep-60 K.LPPSLGNK[136.11]PVLPLIGK[136.11].L sp|Q9UKJ3|GPTC8_HUMAN 1 1658.0466 0.59 35552 20647 3 1658.047696 553.6895 G patch domain-containing protein 8 OS=Homo sapiens OX=9606 GN=GPATCH8 PE=1 SV=2 10 3370.4 - 466658 - - - 0.6827 - 2.041 0.48 - 82.8 1 2 0 0.0011 16 0 0 0 4.24E+06 7.15E+06 - - - 5.7218 0.8845 221125_WJC_METTL3_EV_vs_WT_F03.20648.20648.2 0.702 30-Jul K.LGLQC[160.03]LPSDGVQNVNQ.- sp|P41440|S19A1_HUMAN 1 1740.8465 - 35553 20648 2 1740.841209 871.4305 Reduced folate transporter OS=Homo sapiens OX=9606 GN=SLC19A1 PE=1 SV=3 3.8 3370.6 - 403888 - - - -3.0301 - 1.369 0.018 - 107 1 2 0 -0.0053 16 0 0 0 - - - - - -0.0555 1 221125_WJC_METTL3_EV_vs_WT_F03.20649.20649.3 0.0362 Dec-36 K.DYAFIHFDER.D "sp|O60506|HNRPQ_HUMAN,tr|A0A7I2YQV8|A0A7I2YQV8_HUMAN,tr|A0A7I2YQN2|A0A7I2YQN2_HUMAN,tr|A0A7I2V4Z0|A0A7I2V4Z0_HUMAN,tr|B7Z645|B7Z645_HUMAN,tr|A0A7I2V2F2|A0A7I2V2F2_HUMAN,tr|A0A7I2V346|A0A7I2V346_HUMAN,tr|A0A7I2V309|A0A7I2V309_HUMAN" 8 1311.5884 1.25 35554 20649 3 1311.589528 438.2034 Heterogeneous nuclear ribonucleoprotein Q OS=Homo sapiens OX=9606 GN=SYNCRIP PE=1 SV=2 4.54 3370.7 - 403681 - - - 0.8593 - 1.991 0.506 - 256.3 1 2 0 0.0011 10 0 0 0 2.33E+07 1.86E+07 - - - 6.1922 1 221125_WJC_METTL3_EV_vs_WT_F03.20653.20653.3 4.07E-06 15/72 R.ILSAENIPNLPPGGGLAGK[136.11].R "sp|O75688|PPM1B_HUMAN,tr|B8ZZF0|B8ZZF0_HUMAN,tr|A0A3B3IS24|A0A3B3IS24_HUMAN,tr|C9JIR6|C9JIR6_HUMAN" 4 1825.0189 3.85 35556 20653 3 1825.018447 609.3469 Protein phosphatase 1B OS=Homo sapiens OX=9606 GN=PPM1B PE=1 SV=1 6 3371.1 - 2.68E+06 - - - -0.2477 - 2.938 0.505 - 234.4 1 2 0 -0.0005 19 0 0 0 2.26E+08 5.87E+07 - - - 6.8179 0.9999 221125_WJC_METTL3_EV_vs_WT_F03.20654.20654.3 1.59E-08 16/60 K.GAGAFGYFEVTHDITK.Y sp|P04040|CATA_HUMAN 1 1711.8206 13.99 35557 20654 3 1711.814885 571.6141 Catalase OS=Homo sapiens OX=9606 GN=CAT PE=1 SV=3 5.32 3371.2 - 2.54E+06 - - - -3.3304 - 2.91 0.568 - 213.1 1 2 0 -0.0057 16 0 0 0 2.68E+07 1.92E+06 - - - 7.6118 0.9999 221125_WJC_METTL3_EV_vs_WT_F03.20655.20655.3 0.00167 13/48 K.LESALTELEQLR[166.11]K[136.11].S sp|P12270|TPR_HUMAN 1 1546.8685 6.57 35558 20655 3 1546.868915 516.6301 Nucleoprotein TPR OS=Homo sapiens OX=9606 GN=TPR PE=1 SV=3 4.79 3371.2 - 3.72E+06 - - - 0.2405 - 2.662 0.417 - 241.4 1 2 0 0.0004 13 0 0 0 2.43E+08 3.70E+07 - - - 5.8436 1 221125_WJC_METTL3_EV_vs_WT_F03.20657.20657.2 1.39E-07 16/28 K.QDLPNAMAISEMTDK[136.11].L "sp|P18085|ARF4_HUMAN,tr|C9JAK5|C9JAK5_HUMAN,tr|U3KQF2|U3KQF2_HUMAN" 3 1670.7735 0.87 35560 20657 2 1670.772437 836.394 ADP-ribosylation factor 4 OS=Homo sapiens OX=9606 GN=ARF4 PE=1 SV=3 4.03 3371.4 - 1.83E+06 - - - -0.641 - 3.018 0.608 - 763.1 1 2 0 -0.0011 15 0 0 0 1.75E+07 2.02E+07 - - - 6.247 1 221125_WJC_METTL3_EV_vs_WT_F03.20660.20660.2 3.27E-08 13/24 K.TTEMETIYDLGTK[136.11].M "sp|Q9Y230|RUVB2_HUMAN,tr|M0R0Y3|M0R0Y3_HUMAN,tr|X6R2L4|X6R2L4_HUMAN" 3 1508.716 0.73 35563 20660 2 1508.717602 755.3653 RuvB-like 2 OS=Homo sapiens OX=9606 GN=RUVBL2 PE=1 SV=3 4.14 3371.6 - 1.51E+06 - - - 1.0777 - 2.599 0.595 - 659.7 1 2 0 0.0016 13 0 0 0 1.36E+07 1.87E+07 - - - 5.8865 1 221125_WJC_METTL3_EV_vs_WT_F03.20661.20661.3 0.919 13/36 K.DYAFIHFDER[166.11].D "sp|O60506|HNRPQ_HUMAN,tr|A0A7I2YQV8|A0A7I2YQV8_HUMAN,tr|A0A7I2YQN2|A0A7I2YQN2_HUMAN,tr|A0A7I2V4Z0|A0A7I2V4Z0_HUMAN,tr|B7Z645|B7Z645_HUMAN,tr|A0A7I2V2F2|A0A7I2V2F2_HUMAN,tr|A0A7I2V346|A0A7I2V346_HUMAN,tr|A0A7I2V309|A0A7I2V309_HUMAN" 8 1321.5967 1.26 35564 20661 3 1321.596047 441.5395 Heterogeneous nuclear ribonucleoprotein Q OS=Homo sapiens OX=9606 GN=SYNCRIP PE=1 SV=2 4.54 3371.7 - 1.48E+06 - - - -0.4722 - 2.459 0.481 - 290.7 1 2 0 -0.0006 10 0 0 0 2.33E+07 1.85E+07 - - - 6.5302 0.9998 221125_WJC_METTL3_EV_vs_WT_F03.20663.20663.2 1.16E-05 26-Nov K.ADTSSQGALVFLSK[136.11].D sp|Q7Z417|NUFP2_HUMAN 1 1430.7497 3.92 35566 20663 2 1430.751001 716.3821 Nuclear fragile X mental retardation-interacting protein 2 OS=Homo sapiens OX=9606 GN=NUFIP2 PE=1 SV=1 5.88 3371.9 - 1.12E+06 - - - 0.938 - 2.285 0.507 - 386.7 1 2 0 0.0013 14 0 0 0 3.52E+07 8.98E+06 - - - 4.859 1 221125_WJC_METTL3_EV_vs_WT_F03.20667.20667.2 3.66E-10 15/30 K.K[136.11]PELVISYLPPGMASK[136.11].L "sp|P78347|GTF2I_HUMAN,tr|A0A494C1K3|A0A494C1K3_HUMAN" 2 1744.9768 2.58 35570 20667 2 1744.974122 873.4957 General transcription factor II-I OS=Homo sapiens OX=9606 GN=GTF2I PE=1 SV=2 8.5 3372.4 - 274299 - - - -1.5513 - 3.179 0.596 - 516.5 1 2 0 -0.0027 16 0 0 0 6.13E+06 2.38E+06 - - - 6.2857 1 221125_WJC_METTL3_EV_vs_WT_F03.20672.20672.2 1.17E-08 24-Dec K.TTEMETIYDLGTK.M "sp|Q9Y230|RUVB2_HUMAN,tr|M0R0Y3|M0R0Y3_HUMAN,tr|X6R2L4|X6R2L4_HUMAN" 3 1500.7018 0.72 35573 20672 2 1500.701436 751.3582 RuvB-like 2 OS=Homo sapiens OX=9606 GN=RUVBL2 PE=1 SV=3 4.14 3373 - 2.02E+06 - - - -0.2266 - 2.385 0.626 - 482.6 1 2 0 -0.0003 13 0 0 0 1.36E+07 1.89E+07 - - - 5.8954 0.9997 221125_WJC_METTL3_EV_vs_WT_F03.20674.20674.3 0.000865 16/52 K.VEIAGPGFINVHLR.K sp|P54136|SYRC_HUMAN 1 1520.8463 0.28 35575 20674 3 1520.853096 507.9561 "Arginine--tRNA ligase, cytoplasmic OS=Homo sapiens OX=9606 GN=RARS1 PE=1 SV=2" 6.72 3373.1 - 4.11E+06 - - - 4.4377 - 2.948 0.452 - 451.8 1 2 0 0.0067 14 0 0 0 2.58E+07 9.23E+07 - - - 6.4506 0.9999 221125_WJC_METTL3_EV_vs_WT_F03.20676.20676.3 6.87E-07 26/64 R.YPNIELSYEVVDK[136.11]DSIR[166.11].S sp|O75643|U520_HUMAN 1 2057.0436 2.37 35577 20676 3 2057.044328 686.6885 U5 small nuclear ribonucleoprotein 200 kDa helicase OS=Homo sapiens OX=9606 GN=SNRNP200 PE=1 SV=2 4.32 3373.2 - 981789 - - - 0.351 - 2.69 0.484 - 359.1 1 2 1 0.0007 17 0 0 0 2.35E+07 9.89E+06 - - - 6.4358 1 221125_WJC_METTL3_EV_vs_WT_F03.20684.20684.2 2.26E-09 19/32 K.LPQVAEEISGPLTSANK.L "sp|O75955|FLOT1_HUMAN,tr|A0A140T9W4|A0A140T9W4_HUMAN,tr|A0A140T9R1|A0A140T9R1_HUMAN,tr|A0A140T974|A0A140T974_HUMAN" 4 1752.9258 2.64 35585 20684 2 1752.925457 877.4702 Flotillin-1 OS=Homo sapiens OX=9606 GN=FLOT1 PE=1 SV=3 4.53 3374.3 - 442463 - - - -0.1837 - 3.723 0.669 - 1286.5 1 2 0 -0.0003 17 0 0 0 4.39E+06 1.67E+06 - - - 7.214 0.9999 221125_WJC_METTL3_EV_vs_WT_F03.20685.20685.3 4.36E-05 Dec-52 K.DHMVSPTAVAFLER.N "sp|O60499|STX10_HUMAN,tr|K7EIY4|K7EIY4_HUMAN,tr|Q5U8S2|Q5U8S2_HUMAN,tr|K7EPP9|K7EPP9_HUMAN,tr|K7EJ05|K7EJ05_HUMAN,tr|X6R2W0|X6R2W0_HUMAN,tr|K7ELY2|K7ELY2_HUMAN" 7 1571.7766 0.69 35586 20685 3 1571.775142 524.9328 Syntaxin-10 OS=Homo sapiens OX=9606 GN=STX10 PE=1 SV=1 5.32 3374.4 - 350614 - - - -0.9359 - 2.209 0.407 - 152.4 1 2 0 -0.0015 14 0 0 0 3.31E+06 4.84E+06 - - - 5.1834 1 221125_WJC_METTL3_EV_vs_WT_F03.20692.20692.3 0.00027 16/44 K.NVVLQTLEGHLR.S "sp|Q14254|FLOT2_HUMAN,tr|E7EMK3|E7EMK3_HUMAN,tr|J3QLD9|J3QLD9_HUMAN" 3 1377.7728 1.4 35591 20692 3 1377.772696 460.2649 Flotillin-2 OS=Homo sapiens OX=9606 GN=FLOT2 PE=1 SV=2 6.75 3375.1 - 2.59E+06 - - - -0.1103 - 2.81 0.412 - 304.1 1 2 0 -0.0002 12 0 0 0 1.77E+07 1.27E+07 - - - 5.9972 1 221125_WJC_METTL3_EV_vs_WT_F03.20694.20694.3 1.96E-06 Nov-56 K.EISFAYEVLSNPEK[136.11]R[166.11].E sp|O60884|DNJA2_HUMAN 1 1798.922 0.54 35593 20694 3 1798.923979 600.648 DnaJ homolog subfamily A member 2 OS=Homo sapiens OX=9606 GN=DNAJA2 PE=1 SV=1 4.79 3375.3 - 2.09E+06 - - - 1.0806 - 2.802 0.524 - 148.7 1 2 0 0.0019 15 0 0 0 4.26E+07 7.83E+07 - - - 7.0701 1 221125_WJC_METTL3_EV_vs_WT_F03.20695.20695.2 1.73E-09 15/28 K.GYGFVDFDSPAAAQK.A "sp|Q6XE24|RBMS3_HUMAN,sp|P29558|RBMS1_HUMAN,tr|C9JIJ9|C9JIJ9_HUMAN,tr|C9J9B2|C9J9B2_HUMAN,tr|E7ETU5|E7ETU5_HUMAN,tr|F6Y5H0|F6Y5H0_HUMAN,tr|E7EPF2|E7EPF2_HUMAN,tr|A0A1B0GUW5|A0A1B0GUW5_HUMAN" 8 1571.7256 1.81 35594 20695 2 1571.728677 786.8701 "RNA-binding motif, single-stranded-interacting protein 3 OS=Homo sapiens OX=9606 GN=RBMS3 PE=1 SV=1" 4.21 3375.3 - 2.02E+06 - - - 1.9431 - 2.986 0.696 - 900.8 1 2 0 0.0031 15 0 0 0 1.81E+08 9.99E+07 - - - 6.8702 0.9998 221125_WJC_METTL3_EV_vs_WT_F03.20697.20697.2 1.43E-05 20-Oct K.NNSFVNEIISR[166.11].L sp|P43246|MSH2_HUMAN 1 1301.6603 0.69 35596 20697 2 1301.662254 651.8374 DNA mismatch repair protein Msh2 OS=Homo sapiens OX=9606 GN=MSH2 PE=1 SV=1 6 3375.5 - 1.95E+06 - - - 1.475 - 2.367 0.498 - 484.7 1 2 0 0.0019 11 0 0 0 8.04E+06 1.16E+07 - - - 5.0495 0.9999 221125_WJC_METTL3_EV_vs_WT_F03.20698.20698.3 0.000205 17/44 K.NVVLQTLEGHLR[166.11].S "sp|Q14254|FLOT2_HUMAN,tr|E7EMK3|E7EMK3_HUMAN,tr|J3QLD9|J3QLD9_HUMAN" 3 1387.7811 1.4 35597 20698 3 1387.780472 463.601 Flotillin-2 OS=Homo sapiens OX=9606 GN=FLOT2 PE=1 SV=2 6.75 3375.5 - 1.76E+06 - - - -0.4655 - 2.758 0.377 - 395.6 1 2 0 -0.0006 12 0 0 0 1.77E+07 1.27E+07 - - - 5.5551 1 221125_WJC_METTL3_EV_vs_WT_F03.20701.20701.3 2.19E-07 15/48 R.HLVSPEALDLLDK[136.11].L "sp|P19784|CSK22_HUMAN,tr|H3BNI9|H3BNI9_HUMAN,tr|H3BSA1|H3BSA1_HUMAN" 3 1456.8017 1.48 35600 20701 3 1456.804518 486.6078 Casein kinase II subunit alpha' OS=Homo sapiens OX=9606 GN=CSNK2A2 PE=1 SV=1 4.54 3375.8 - 1.08E+06 - - - 1.9378 - 2.713 0.539 - 411.1 1 2 0 0.0028 13 0 0 0 5.21E+06 3.51E+06 - - - 7.2546 0.9429 221125_WJC_METTL3_EV_vs_WT_F03.20702.20702.3 0.383 Sep-44 K.TEQSVTPEQQKK.L "sp|Q9BY11|PACN1_HUMAN,tr|F6U236|F6U236_HUMAN" 2 1401.71 0.87 35601 20702 3 1401.713444 468.2439 Protein kinase C and casein kinase substrate in neurons protein 1 OS=Homo sapiens OX=9606 GN=PACSIN1 PE=1 SV=1 5.81 3375.9 - 1.03E+06 - - - 2.4763 - 1.571 0.138 - 74.9 1 2 0 0.0035 12 0 0 0 1.10E+07 1.27E+07 - - - 1.3297 0.9999 221125_WJC_METTL3_EV_vs_WT_F03.20703.20703.3 3.92E-08 14/48 R.HLVSPEALDLLDK.L "sp|P19784|CSK22_HUMAN,tr|H3BNI9|H3BNI9_HUMAN,tr|H3BSA1|H3BSA1_HUMAN" 3 1448.7875 1.48 35602 20703 3 1448.79143 483.9364 Casein kinase II subunit alpha' OS=Homo sapiens OX=9606 GN=CSNK2A2 PE=1 SV=1 4.54 3376 - 1.01E+06 - - - 2.7161 - 2.717 0.508 - 405.7 1 2 0 0.0039 13 0 0 0 5.21E+06 3.51E+06 - - - 6.9126 1 221125_WJC_METTL3_EV_vs_WT_F03.20704.20704.3 4.80E-05 15/52 K.IDAFHYVQLGTAYR[166.11].G "sp|Q9H857|NT5D2_HUMAN,tr|H7C4G8|H7C4G8_HUMAN,tr|C9J036|C9J036_HUMAN" 3 1662.8394 0.59 35603 20704 3 1662.842922 555.2871 5'-nucleotidase domain-containing protein 2 OS=Homo sapiens OX=9606 GN=NT5DC2 PE=1 SV=1 6.74 3376.1 - 948178 - - - 2.1415 - 3.083 0.539 - 309.9 1 2 0 0.0036 14 0 0 0 2.47E+06 4.19E+06 - - - 7.5405 1 221125_WJC_METTL3_EV_vs_WT_F03.20705.20705.2 4.04E-10 16/28 K.VGEATETALTC[160.03]LVEK.M "sp|P16615|AT2A2_HUMAN,sp|Q93084|AT2A3_HUMAN,tr|H7C5W9|H7C5W9_HUMAN" 3 1619.8076 1.23 35604 20705 2 1619.80817 810.9111 Sarcoplasmic\endoplasmic reticulum calcium ATPase 2 OS=Homo sapiens OX=9606 GN=ATP2A2 PE=1 SV=1 4.25 3376.2 - 929874 - - - 0.3284 - 3.568 0.627 - 1124.8 1 2 0 0.0005 15 0 0 0 1.63E+07 1.33E+07 - - - 6.7991 1 221125_WJC_METTL3_EV_vs_WT_F03.20707.20707.2 2.52E-11 19/28 A.TVDNANVLLQIDNAR.L sp|P02533|K1C14_HUMAN 1 1654.8638 37.16 35606 20707 2 1654.868476 828.4392 "Keratin, type I cytoskeletal 14 OS=Homo sapiens OX=9606 GN=KRT14 PE=1 SV=4" 4.21 3376.5 - 835395 - - - 2.7966 - 3.489 0.696 - 1451.6 1 1 0 0.0046 15 0 0 0 5.24E+06 1.41E+05 - - - 7.2524 1 221125_WJC_METTL3_EV_vs_WT_F03.20708.20708.2 5.45E-09 15/28 K.VGEATETALTC[160.03]LVEK[136.11].M "sp|P16615|AT2A2_HUMAN,sp|Q93084|AT2A3_HUMAN,tr|H7C5W9|H7C5W9_HUMAN" 3 1627.8218 1.16 35607 20708 2 1627.824904 814.9182 Sarcoplasmic\endoplasmic reticulum calcium ATPase 2 OS=Homo sapiens OX=9606 GN=ATP2A2 PE=1 SV=1 4.25 3376.6 - 808253 - - - 1.8835 - 3.502 0.548 - 986.1 1 2 0 0.0031 15 0 0 0 7.99E+06 6.89E+06 - - - 6.1689 0.9993 221125_WJC_METTL3_EV_vs_WT_F03.20714.20714.3 2.94E-05 Sep-48 R.TALQEVYTLAEHR.R "sp|O15397|IPO8_HUMAN,tr|H0YH64|H0YH64_HUMAN" 2 1529.7838 1.39 35612 20714 3 1529.785696 510.9352 Importin-8 OS=Homo sapiens OX=9606 GN=IPO8 PE=1 SV=2 5.37 3377.3 - 4.71E+06 - - - 1.2348 - 2.248 0.272 - 130.1 1 2 0 0.0019 13 0 0 0 3.12E+07 2.24E+07 - - - 3.7683 0.9978 221125_WJC_METTL3_EV_vs_WT_F03.20716.20716.3 0.00109 Nov-48 R.TALQEVYTLAEHR[166.11].R "sp|O15397|IPO8_HUMAN,tr|H0YH64|H0YH64_HUMAN" 2 1539.7921 1.4 35614 20716 3 1539.792777 514.2713 Importin-8 OS=Homo sapiens OX=9606 GN=IPO8 PE=1 SV=2 5.37 3377.4 - 3.31E+06 - - - 0.4546 - 2.427 0.175 - 212.8 2 2 0 0.0007 13 0 0 0 3.15E+07 2.25E+07 - - - 2.7555 1 221125_WJC_METTL3_EV_vs_WT_F03.20717.20717.3 7.17E-07 19/56 K.EISFAYEVLSNPEKR.E sp|O60884|DNJA2_HUMAN 1 1780.8996 0.54 35615 20717 3 1780.902908 594.6405 DnaJ homolog subfamily A member 2 OS=Homo sapiens OX=9606 GN=DNAJA2 PE=1 SV=1 4.79 3377.4 - 2.85E+06 - - - 1.8771 - 3.322 0.535 - 502.3 1 2 0 0.0033 15 0 0 0 4.26E+07 7.83E+07 - - - 7.6365 0.9999 221125_WJC_METTL3_EV_vs_WT_F03.20719.20719.3 9.57E-06 18/60 R.LDQEVAEVDKNIELLK.K "sp|Q99816|TS101_HUMAN,tr|F5H442|F5H442_HUMAN" 2 1854.9939 1.93 35617 20719 3 1854.996492 619.3386 Tumor susceptibility gene 101 protein OS=Homo sapiens OX=9606 GN=TSG101 PE=1 SV=2 4.18 3377.5 - 1.94E+06 - - - 1.4194 - 4.051 0.522 - 498.6 1 2 1 0.0026 16 0 0 0 1.88E+07 9.76E+06 - - - 7.9486 1 221125_WJC_METTL3_EV_vs_WT_F03.20721.20721.3 1.68E-08 18/56 R.VTTVTEIGK[136.11]DVIGLR[166.11].L "sp|P53621|COPA_HUMAN,tr|A0A3B3ISC6|A0A3B3ISC6_HUMAN,tr|A0A3B3IS84|A0A3B3IS84_HUMAN,tr|A0A3B3ITI7|A0A3B3ITI7_HUMAN,tr|A0A3B3IT15|A0A3B3IT15_HUMAN" 5 1617.942 0.25 35619 20721 3 1617.944 540.3213 Coatomer subunit alpha OS=Homo sapiens OX=9606 GN=COPA PE=1 SV=2 6.04 3377.7 - 1.43E+06 - - - 1.2102 - 3.706 0.64 - 560.3 1 2 1 0.002 15 0 0 0 8.62E+06 3.46E+07 - - - 9.093 0.9681 221125_WJC_METTL3_EV_vs_WT_F03.20723.20723.3 0.0115 Nov-72 K.GLQAQIASSGLTVEVDAPK[136.11].S "sp|P05783|K1C18_HUMAN,tr|F8VZY9|F8VZY9_HUMAN" 2 1891.0142 0.34 35621 20723 3 1891.020697 631.3453 "Keratin, type I cytoskeletal 18 OS=Homo sapiens OX=9606 GN=KRT18 PE=1 SV=2" 4.37 3377.9 - 1.30E+06 - - - 3.432 - 2.245 0.141 - 91.7 1 2 0 0.0065 19 0 0 0 8.28E+06 2.41E+07 - - - 2.097 0.9998 221125_WJC_METTL3_EV_vs_WT_F03.20725.20725.2 0.0118 14/32 K.VAFGSLAANGPTTLVDK[136.11].V sp|Q9UKX7|NUP50_HUMAN 1 1667.8974 0.49 35623 20725 2 1667.894695 834.956 Nuclear pore complex protein Nup50 OS=Homo sapiens OX=9606 GN=NUP50 PE=1 SV=2 5.81 3378.1 - 1.10E+06 - - - -1.6134 - 2.704 0.42 - 403.4 1 2 0 -0.0027 17 0 0 0 3.24E+06 6.65E+06 - - - 4.5879 1 221125_WJC_METTL3_EV_vs_WT_F03.20726.20726.2 2.04E-10 16/32 K.VAFGSLAANGPTTLVDK.V sp|Q9UKX7|NUP50_HUMAN 1 1659.8832 0.71 35624 20726 2 1659.887707 830.9489 Nuclear pore complex protein Nup50 OS=Homo sapiens OX=9606 GN=NUP50 PE=1 SV=2 5.81 3378.3 - 983243 - - - 2.7237 - 3.379 0.557 - 862.1 1 2 0 0.0045 17 0 0 0 1.50E+07 2.13E+07 - - - 6.1471 1 221125_WJC_METTL3_EV_vs_WT_F03.20728.20728.2 1.71E-09 19/34 K.LASGEDDPFDSDFSC[160.03]PVK.L "sp|Q99567|NUP88_HUMAN,tr|J3KMX1|J3KMX1_HUMAN" 2 1984.836 2.25 35626 20728 2 1984.839978 993.4253 Nuclear pore complex protein Nup88 OS=Homo sapiens OX=9606 GN=NUP88 PE=1 SV=2 3.71 3378.5 - 588208 - - - 1.9851 - 3.834 0.685 - 985.6 1 2 0 0.0039 18 0 0 0 5.04E+06 2.24E+06 - - - 7.4032 0.9998 221125_WJC_METTL3_EV_vs_WT_F03.20730.20730.2 0.00923 26-Dec K.LGGSAVISLEGK[136.11]PL.- "sp|P23528|COF1_HUMAN,tr|G3V1A4|G3V1A4_HUMAN,tr|E9PK25|E9PK25_HUMAN" 3 1347.7853 2.47 35628 20730 2 1347.785656 674.8999 Cofilin-1 OS=Homo sapiens OX=9606 GN=CFL1 PE=1 SV=3 6 3378.7 - 549627 - - - 0.2515 - 2.303 0.417 - 403.9 1 2 0 0.0003 14 0 0 0 4.78E+06 1.93E+06 - - - 4.2143 0.9998 221125_WJC_METTL3_EV_vs_WT_F03.20731.20731.2 5.01E-08 Dec-32 R.EANSIIITPGYGLC[160.03]AAK[136.11].A "sp|Q13423|NNTM_HUMAN,tr|E9PCX7|E9PCX7_HUMAN,tr|A0A590UK15|A0A590UK15_HUMAN" 3 1784.9222 0.27 35629 20731 2 1784.920647 893.4684 "NAD(P) transhydrogenase, mitochondrial OS=Homo sapiens OX=9606 GN=NNT PE=1 SV=3" 6.09 3378.9 - 515929 - - - -0.8818 - 2.548 0.447 - 297.9 1 2 0 -0.0016 17 0 0 0 8.56E+05 3.18E+06 - - - 4.6415 0.9999 221125_WJC_METTL3_EV_vs_WT_F03.20733.20733.3 0.000656 Nov-48 K.MFIGGLSWDTTKK.D "sp|Q14103|HNRPD_HUMAN,tr|H0Y8G5|H0Y8G5_HUMAN,tr|D6RF44|D6RF44_HUMAN,tr|D6RD83|D6RD83_HUMAN,tr|D6RBQ9|D6RBQ9_HUMAN,tr|D6RAF8|D6RAF8_HUMAN,tr|H0YA96|H0YA96_HUMAN" 7 1482.7541 1.2 35630 20733 3 1482.756125 495.2586 Heterogeneous nuclear ribonucleoprotein D0 OS=Homo sapiens OX=9606 GN=HNRNPD PE=1 SV=1 8.35 3379.1 - 3.28E+06 - - - 1.3751 - 2.151 0.456 - 138.6 1 2 0 0.002 13 0 0 0 1.34E+08 1.12E+08 - - - 5.7 1 221125_WJC_METTL3_EV_vs_WT_F03.20736.20736.2 7.27E-09 15/28 K.GYGFVDFDSPAAAQK[136.11].A "sp|Q6XE24|RBMS3_HUMAN,sp|P29558|RBMS1_HUMAN,tr|C9JIJ9|C9JIJ9_HUMAN,tr|C9J9B2|C9J9B2_HUMAN,tr|E7ETU5|E7ETU5_HUMAN,tr|F6Y5H0|F6Y5H0_HUMAN,tr|E7EPF2|E7EPF2_HUMAN,tr|A0A1B0GUW5|A0A1B0GUW5_HUMAN" 8 1579.7398 1.82 35633 20736 2 1579.741663 790.8772 "RNA-binding motif, single-stranded-interacting protein 3 OS=Homo sapiens OX=9606 GN=RBMS3 PE=1 SV=1" 4.21 3379.2 - 6.08E+06 - - - 1.1647 - 2.846 0.676 - 817 1 2 0 0.0018 15 0 0 0 1.81E+08 9.99E+07 - - - 6.6048 0.9996 221125_WJC_METTL3_EV_vs_WT_F03.20738.20738.2 3.33E-06 20-Nov R.SNLGSVVLQLK.K sp|O43143|DHX15_HUMAN 1 1156.6816 0.77 35635 20738 2 1156.684678 579.3481 Pre-mRNA-splicing factor ATP-dependent RNA helicase DHX15 OS=Homo sapiens OX=9606 GN=DHX15 PE=1 SV=2 8.47 3379.3 - 2.08E+06 - - - 2.6844 - 2.31 0.487 - 397.7 1 2 0 0.0031 11 0 0 0 1.01E+07 1.30E+07 - - - 4.902 1 221125_WJC_METTL3_EV_vs_WT_F03.20739.20739.2 3.97E-12 21/36 R.DILELGGPEGDAASGTISK.K "sp|Q9NPF5|DMAP1_HUMAN,tr|Q5TG39|Q5TG39_HUMAN,tr|Q5TG38|Q5TG38_HUMAN,tr|Q5TG40|Q5TG40_HUMAN,tr|Q5TG36|Q5TG36_HUMAN" 5 1828.9054 1.41 35636 20739 2 1828.906732 915.46 DNA methyltransferase 1-associated protein 1 OS=Homo sapiens OX=9606 GN=DMAP1 PE=1 SV=1 3.92 3379.4 - 1.89E+06 - - - 0.7075 - 3.899 0.678 - 1425.9 1 2 0 0.0013 19 0 0 0 2.65E+07 1.88E+07 - - - 7.3937 0.976 221125_WJC_METTL3_EV_vs_WT_F03.20741.20741.3 0.000831 Dec-40 R.IQHPSNVLHFF.N "sp|P14866|HNRPL_HUMAN,tr|M0QYT0|M0QYT0_HUMAN,tr|A0A3B3ITJ4|A0A3B3ITJ4_HUMAN,tr|M0QXS5|M0QXS5_HUMAN" 4 1337.6881 - 35638 20741 3 1337.68861 446.9033 Heterogeneous nuclear ribonucleoprotein L OS=Homo sapiens OX=9606 GN=HNRNPL PE=1 SV=2 6.92 3379.6 - 1.81E+06 - - - 0.4141 - 1.906 0.364 - 127.8 1 1 0 0.0006 11 0 0 0 - - - - - 4.4304 1 221125_WJC_METTL3_EV_vs_WT_F03.20743.20743.2 1.42E-06 18/30 R.ADLTGISPSPNLYLSK.L sp|Q96P63|SPB12_HUMAN 1 1674.8829 999 35640 20743 2 1674.887579 838.4487 Serpin B12 OS=Homo sapiens OX=9606 GN=SERPINB12 PE=1 SV=1 5.88 3379.8 - 1.62E+06 - - - 2.8223 - 3.607 0.534 - 1100.5 1 2 0 0.0047 16 0 0 0 9.90E+07 0.00E+00 - - - 6.1377 1 221125_WJC_METTL3_EV_vs_WT_F03.20744.20744.3 5.08E-11 17/80 R.GQVGGEINVEMDAAPGVDLSR.L "sp|Q04695|K1C17_HUMAN,tr|K7EPJ9|K7EPJ9_HUMAN,tr|K7ESE1|K7ESE1_HUMAN,tr|F5GWP8|F5GWP8_HUMAN" 4 2113.011 999 35641 20744 3 2113.015115 705.3443 "Keratin, type I cytoskeletal 17 OS=Homo sapiens OX=9606 GN=KRT17 PE=1 SV=2" 3.92 3379.9 - 1.43E+06 - - - 1.9555 - 3.353 0.556 - 243.1 1 2 0 0.0041 21 0 0 0 1.52E+07 0.00E+00 - - - 7.6383 1 221125_WJC_METTL3_EV_vs_WT_F03.20745.20745.2 4.30E-14 19/32 R.AAFGLSEAGFNTAC[160.03]VTK[136.11].L "sp|P31040|SDHA_HUMAN,tr|A0A087X1I3|A0A087X1I3_HUMAN,tr|D6RFM5|D6RFM5_HUMAN,tr|A0A494C1T6|A0A494C1T6_HUMAN" 4 1750.844 0.6 35642 20745 2 1750.846248 876.4293 "Succinate dehydrogenase [ubiquinone] flavoprotein subunit, mitochondrial OS=Homo sapiens OX=9606 GN=SDHA PE=1 SV=2" 6.04 3380 - 1.41E+06 - - - 1.3005 - 3.84 0.672 - 1425.2 1 2 0 0.0023 17 0 0 0 7.37E+06 1.23E+07 - - - 7.3116 1 221125_WJC_METTL3_EV_vs_WT_F03.20747.20747.2 3.64E-10 16/28 R.NIAFFSTNC[160.03]VEGTAR[166.11].G sp|P05023|AT1A1_HUMAN 1 1695.7914 1.56 35644 20747 2 1695.793309 848.903 Sodium\potassium-transporting ATPase subunit alpha-1 OS=Homo sapiens OX=9606 GN=ATP1A1 PE=1 SV=1 5.99 3380.2 - 1.07E+06 - - - 1.111 - 3.217 0.681 - 907.4 1 2 0 0.0019 15 0 0 0 1.67E+07 1.07E+07 - - - 6.943 1 221125_WJC_METTL3_EV_vs_WT_F03.20748.20748.3 4.09E-08 18/72 R.MDSFDEDLARPSGLLAQER.K "sp|Q9Y2W1|TR150_HUMAN,tr|A0A3B3ITZ9|A0A3B3ITZ9_HUMAN" 2 2149.011 2.3 35645 20748 3 2149.011943 717.3443 Thyroid hormone receptor-associated protein 3 OS=Homo sapiens OX=9606 GN=THRAP3 PE=1 SV=2 4.1 3380.4 - 819238 - - - 0.4467 - 2.67 0.597 - 440.7 1 2 0 0.001 19 0 0 0 1.13E+08 4.90E+07 - - - 7.6085 1 221125_WJC_METTL3_EV_vs_WT_F03.20750.20750.2 4.59E-09 14/24 R.TSAC[160.03]GLFSVC[160.03]YPR[166.11].V "sp|P30153|2AAA_HUMAN,sp|P30154|2AAB_HUMAN,tr|C9J9C1|C9J9C1_HUMAN" 3 1526.6885 0.59 35647 20750 2 1526.692451 764.3515 Serine\threonine-protein phosphatase 2A 65 kDa regulatory subunit A alpha isoform OS=Homo sapiens OX=9606 GN=PPP2R1A PE=1 SV=4 7.74 3380.6 - 779981 - - - 2.5618 - 2.92 0.66 - 715.8 1 2 0 0.0039 13 0 0 0 9.77E+06 1.65E+07 - - - 6.6648 1 221125_WJC_METTL3_EV_vs_WT_F03.20751.20751.2 1.18E-06 16/28 K.TIIDFEPNETTDLEK[136.11].S "sp|P42694|HELZ_HUMAN,tr|J3QRR8|J3QRR8_HUMAN,tr|J3QS41|J3QS41_HUMAN,tr|A0A075B6R3|A0A075B6R3_HUMAN" 4 1771.8607 3.14 35648 20751 2 1771.868454 886.9376 Probable helicase with zinc finger domain OS=Homo sapiens OX=9606 GN=HELZ PE=1 SV=2 3.83 3380.7 - 692092 - - - 4.3615 - 3.152 0.577 - 531.5 1 2 0 0.0077 15 0 0 0 5.33E+07 1.70E+07 - - - 6.1228 0.9998 221125_WJC_METTL3_EV_vs_WT_F03.20752.20752.3 5.55E-06 20/56 R.VTTVTEIGKDVIGLR.L "sp|P53621|COPA_HUMAN,tr|A0A3B3ISC6|A0A3B3ISC6_HUMAN,tr|A0A3B3IS84|A0A3B3IS84_HUMAN,tr|A0A3B3ITI7|A0A3B3ITI7_HUMAN,tr|A0A3B3IT15|A0A3B3IT15_HUMAN" 5 1599.9196 0.24 35649 20752 3 1599.923473 534.3138 Coatomer subunit alpha OS=Homo sapiens OX=9606 GN=COPA PE=1 SV=2 6.04 3380.9 - 589171 - - - 2.4382 - 3.448 0.524 - 437.1 1 2 1 0.0039 15 0 0 0 8.08E+06 3.36E+07 - - - 7.6109 0.9848 221125_WJC_METTL3_EV_vs_WT_F03.20754.20754.2 1.38E-05 26-Nov R.K[136.11]TPTLASPVPTTPF.L "sp|Q9NRA8|4ET_HUMAN,tr|B1AKL4|B1AKL4_HUMAN" 2 1463.8115 1.46 35650 20754 2 1463.813932 732.913 Eukaryotic translation initiation factor 4E transporter OS=Homo sapiens OX=9606 GN=EIF4ENIF1 PE=1 SV=2 8.75 3381.2 - 873947 - - - 1.6402 - 1.995 0.522 - 182.1 1 1 0 0.0024 14 0 0 0 1.71E+07 1.18E+07 - - - 4.6289 1 221125_WJC_METTL3_EV_vs_WT_F03.20755.20755.2 6.87E-09 20/32 R.AAFGLSEAGFNTAC[160.03]VTK.L "sp|P31040|SDHA_HUMAN,tr|A0A087X1I3|A0A087X1I3_HUMAN,tr|D6RFM5|D6RFM5_HUMAN,tr|A0A494C1T6|A0A494C1T6_HUMAN" 4 1742.8298 0.59 35651 20755 2 1742.824383 872.4222 "Succinate dehydrogenase [ubiquinone] flavoprotein subunit, mitochondrial OS=Homo sapiens OX=9606 GN=SDHA PE=1 SV=2" 6.04 3381.3 - 860595 - - - -3.0915 - 3.609 0.639 - 1136.6 1 2 0 -0.0054 17 0 0 0 7.22E+06 1.23E+07 - - - 6.9143 0.9979 221125_WJC_METTL3_EV_vs_WT_F03.20757.20757.2 2.81E-06 14/24 R.MQLWLNDPNNVEK.L "sp|P39880|CUX1_HUMAN,tr|A0A2R8Y852|A0A2R8Y852_HUMAN,tr|A0A2R8YDI1|A0A2R8YDI1_HUMAN" 3 1599.7715 1.01 35653 20757 2 1599.779883 800.893 Homeobox protein cut-like 1 OS=Homo sapiens OX=9606 GN=CUX1 PE=1 SV=3 4.37 3381.4 - 2.24E+06 - - - 5.2232 - 2.72 0.523 - 628.7 1 2 0 0.0084 13 0 0 0 2.09E+07 2.08E+07 - - - 5.4694 1 221125_WJC_METTL3_EV_vs_WT_F03.20758.20758.2 5.35E-06 15/26 N.AVITVPAYFNDSQR[166.11].Q "sp|P38646|GRP75_HUMAN,sp|P54652|HSP72_HUMAN,sp|P0DMV8|HS71A_HUMAN,sp|P34931|HS71L_HUMAN,sp|P0DMV9|HS71B_HUMAN,sp|P17066|HSP76_HUMAN,tr|H0Y8K0|H0Y8K0_HUMAN,tr|A0A7I2V2S7|A0A7I2V2S7_HUMAN,tr|A0A7I2V2G2|A0A7I2V2G2_HUMAN,tr|Q53FA3|Q53FA3_HUMAN,tr|A0A7I2V3F7|A0A7I2V3F7_HUMAN,tr|A0A7I2YQB2|A0A7I2YQB2_HUMAN,tr|A0A0G2JIW1|A0A0G2JIW1_HUMAN,tr|D6RCD7|D6RCD7_HUMAN" 14 1589.8077 0.1 35654 20758 2 1589.809693 795.9111 "Stress-70 protein, mitochondrial OS=Homo sapiens OX=9606 GN=HSPA9 PE=1 SV=2" 5.88 3381.5 - 1.90E+06 - - - 1.2366 - 2.584 0.603 - 540.2 1 1 0 0.002 14 0 0 0 2.92E+07 2.79E+08 - - - 5.8765 1 221125_WJC_METTL3_EV_vs_WT_F03.20759.20759.2 6.45E-06 15/28 R.NIAFFSTNC[160.03]VEGTAR.G sp|P05023|AT1A1_HUMAN 1 1685.7832 1.56 35655 20759 2 1685.784588 843.8989 Sodium\potassium-transporting ATPase subunit alpha-1 OS=Homo sapiens OX=9606 GN=ATP1A1 PE=1 SV=1 5.99 3381.6 - 1.68E+06 - - - 0.8501 - 3.191 0.604 - 756.8 1 2 0 0.0014 15 0 0 0 1.67E+07 1.07E+07 - - - 6.3544 0.9823 221125_WJC_METTL3_EV_vs_WT_F03.20760.20760.3 0.000279 13/52 N.AVITVPAYFNDSQR[166.11].Q "sp|P38646|GRP75_HUMAN,sp|P54652|HSP72_HUMAN,sp|P0DMV8|HS71A_HUMAN,sp|P34931|HS71L_HUMAN,sp|P0DMV9|HS71B_HUMAN,sp|P17066|HSP76_HUMAN,tr|H0Y8K0|H0Y8K0_HUMAN,tr|A0A7I2V2S7|A0A7I2V2S7_HUMAN,tr|A0A7I2V2G2|A0A7I2V2G2_HUMAN,tr|Q53FA3|Q53FA3_HUMAN,tr|A0A7I2V3F7|A0A7I2V3F7_HUMAN,tr|A0A7I2YQB2|A0A7I2YQB2_HUMAN,tr|A0A0G2JIW1|A0A0G2JIW1_HUMAN,tr|D6RCD7|D6RCD7_HUMAN" 14 1589.8077 0.17 35656 20760 3 1589.811201 530.9432 "Stress-70 protein, mitochondrial OS=Homo sapiens OX=9606 GN=HSPA9 PE=1 SV=2" 5.88 3381.6 - 802302 - - - 2.1852 - 2.25 0.425 - 138.3 1 1 0 0.0035 14 0 0 0 1.30E+07 7.88E+07 - - - 5.4324 0.9985 221125_WJC_METTL3_EV_vs_WT_F03.20761.20761.2 0.00329 26-Dec K.SLPVPGALEQVASR.L "tr|A0A669KBG4|A0A669KBG4_HUMAN,tr|A0A669KAV7|A0A669KAV7_HUMAN,tr|M0QXA7|M0QXA7_HUMAN,tr|A0A669KBH9|A0A669KBH9_HUMAN,tr|B9EGQ5|B9EGQ5_HUMAN" 5 1422.7831 1.11 35657 20761 2 1422.78881 712.3988 Protein Wiz OS=Homo sapiens OX=9606 GN=WIZ PE=1 SV=1 5.72 3381.8 - 792830 - - - 4.0287 - 2.444 0.426 - 341.9 1 2 0 0.0057 14 0 0 0 7.07E+06 6.38E+06 - - - 4.4282 0.9984 221125_WJC_METTL3_EV_vs_WT_F03.20762.20762.3 0.0184 Oct-44 K.EFR[166.11]PEDQPWLLR[166.11].V "sp|P35269|T2FA_HUMAN,tr|M0R0R9|M0R0R9_HUMAN,tr|M0QXD6|M0QXD6_HUMAN,tr|M0R0Z3|M0R0Z3_HUMAN" 4 1604.8214 1.02 35658 20762 3 1604.825551 535.9477 General transcription factor IIF subunit 1 OS=Homo sapiens OX=9606 GN=GTF2F1 PE=1 SV=2 4.68 3381.9 - 735101 - - - 2.5766 - 1.958 0.301 - 201.1 1 2 0 0.0041 12 0 0 0 2.09E+07 2.06E+07 - - - 3.7572 1 221125_WJC_METTL3_EV_vs_WT_F03.20763.20763.2 3.36E-09 13/28 K.EISFAYEVLSNPEK[136.11]R[166.11].E sp|O60884|DNJA2_HUMAN 1 1798.922 0.67 35659 20763 2 1798.926847 900.4683 DnaJ homolog subfamily A member 2 OS=Homo sapiens OX=9606 GN=DNAJA2 PE=1 SV=1 4.79 3382 - 396848 - - - 2.6749 - 2.936 0.653 - 637.6 1 2 0 0.0048 15 0 0 0 2.04E+06 3.04E+06 - - - 6.5105 0.9986 221125_WJC_METTL3_EV_vs_WT_F03.20768.20768.3 0.0485 Nov-56 R.DQDLTQEIAMEHFVK.K "sp|Q9ULX6|AKP8L_HUMAN,tr|A0A7P0TAE3|A0A7P0TAE3_HUMAN" 2 1802.8509 1.11 35662 20768 3 1802.855578 601.9576 A-kinase anchor protein 8-like OS=Homo sapiens OX=9606 GN=AKAP8L PE=1 SV=4 4.31 3382.6 - 7.88E+06 - - - 2.5948 - 1.674 0.355 - 103 1 2 0 0.0047 15 0 0 0 2.82E+07 2.55E+07 - - - 3.841 1 221125_WJC_METTL3_EV_vs_WT_F03.20770.20770.2 3.21E-10 16/28 R.SMGETESGDAFLDLK[136.11].K "sp|Q9NRA8|4ET_HUMAN,tr|B1AKL6|B1AKL6_HUMAN,tr|B1AKL5|B1AKL5_HUMAN,tr|B1AKL4|B1AKL4_HUMAN" 4 1606.7276 1.51 35664 20770 2 1606.729232 804.3711 Eukaryotic translation initiation factor 4E transporter OS=Homo sapiens OX=9606 GN=EIF4ENIF1 PE=1 SV=2 3.92 3382.7 - 1.58E+06 - - - 1.0139 - 2.691 0.68 - 763.7 1 2 0 0.0016 15 0 0 0 3.18E+07 2.11E+07 - - - 6.4967 1 221125_WJC_METTL3_EV_vs_WT_F03.20771.20771.2 2.69E-06 20/36 R.DILELGGPEGDAASGTISK[136.11].K "sp|Q9NPF5|DMAP1_HUMAN,tr|Q5TG39|Q5TG39_HUMAN,tr|Q5TG38|Q5TG38_HUMAN,tr|Q5TG40|Q5TG40_HUMAN,tr|Q5TG36|Q5TG36_HUMAN" 5 1836.9196 1.4 35665 20771 2 1836.922643 919.4671 DNA methyltransferase 1-associated protein 1 OS=Homo sapiens OX=9606 GN=DMAP1 PE=1 SV=1 3.92 3382.8 - 1.37E+06 - - - 1.6359 - 3.461 0.594 - 1070.3 1 2 0 0.003 19 0 0 0 2.63E+07 1.88E+07 - - - 6.4798 0.9999 221125_WJC_METTL3_EV_vs_WT_F03.20773.20773.3 0.00155 Nov-48 R.DLK[136.11]PSNIFLVDTK[136.11].Q "sp|P19525|E2AK2_HUMAN,tr|A0A7P0TAL9|A0A7P0TAL9_HUMAN,tr|A0A7P0TBA9|A0A7P0TBA9_HUMAN" 3 1504.8472 1.07 35667 20773 3 1504.849602 502.623 "Interferon-induced, double-stranded RNA-activated protein kinase OS=Homo sapiens OX=9606 GN=EIF2AK2 PE=1 SV=2" 5.96 3383 - 742141 - - - 1.5995 - 2.144 0.471 - 132.2 1 2 0 0.0024 13 0 0 0 8.80E+06 8.24E+06 - - - 5.8583 0.9996 221125_WJC_METTL3_EV_vs_WT_F03.20774.20774.3 0.000325 Oct-48 R.DLKPSNIFLVDTK.Q "sp|P19525|E2AK2_HUMAN,tr|A0A7P0TAL9|A0A7P0TAL9_HUMAN,tr|A0A7P0TBA9|A0A7P0TBA9_HUMAN" 3 1488.8188 1.07 35668 20774 3 1488.819412 497.2802 "Interferon-induced, double-stranded RNA-activated protein kinase OS=Homo sapiens OX=9606 GN=EIF2AK2 PE=1 SV=2" 5.96 3383.1 - 550389 - - - 0.4144 - 2.07 0.314 - 116.7 1 2 0 0.0006 13 0 0 0 8.80E+06 8.24E+06 - - - 4.0132 1 221125_WJC_METTL3_EV_vs_WT_F03.20779.20779.3 2.42E-08 16/68 R.LQEYGSIFTGAQDPGLQR.R "sp|Q9NQA3|WASH6_HUMAN,sp|A8K0Z3|WASH1_HUMAN,sp|C4AMC7|WASH3_HUMAN,sp|Q6VEQ5|WASH2_HUMAN,tr|A0A7I2YQU6|A0A7I2YQU6_HUMAN" 5 1978.9749 0.84 35672 20779 3 1978.979111 660.6656 WAS protein family homolog 6 OS=Homo sapiens OX=9606 GN=WASH6P PE=1 SV=3 4.37 3383.7 - 1.07E+06 - - - 2.1506 - 3.194 0.516 - 181 1 2 0 0.0043 18 0 0 0 1.47E+07 1.76E+07 - - - 7.1834 1 221125_WJC_METTL3_EV_vs_WT_F03.20782.20782.2 2.46E-11 18/34 K.VLAGETLSVNDPPDVLDR.Q "sp|Q12906|ILF3_HUMAN,tr|K7EQR9|K7EQR9_HUMAN,tr|K7EKJ9|K7EKJ9_HUMAN" 3 1908.9793 1.24 35674 20782 2 1908.98289 955.4969 Interleukin enhancer-binding factor 3 OS=Homo sapiens OX=9606 GN=ILF3 PE=1 SV=3 3.84 3384 - 865347 - - - 1.8953 - 3.681 0.67 - 555 1 2 0 0.0036 18 0 0 0 2.83E+07 2.28E+07 - - - 7.1924 0.9993 221125_WJC_METTL3_EV_vs_WT_F03.20783.20783.2 0.00267 22-Oct R.LNVGGTYFLTTR.Q "sp|Q9NXV2|KCTD5_HUMAN,tr|H3BSS5|H3BSS5_HUMAN" 2 1340.7089 3.89 35675 20783 2 1340.712091 671.3617 BTB\POZ domain-containing protein KCTD5 OS=Homo sapiens OX=9606 GN=KCTD5 PE=1 SV=1 8.75 3384.1 - 621366 - - - 2.4166 - 2.118 0.397 - 281.9 1 2 0 0.0032 12 0 0 0 3.86E+07 9.92E+06 - - - 3.9468 1 221125_WJC_METTL3_EV_vs_WT_F03.20785.20785.2 2.71E-14 16/34 K.LGIYDADGDGDFDVDDAK.V "sp|Q12797|ASPH_HUMAN,tr|E5RHJ2|E5RHJ2_HUMAN,tr|E5RG29|E5RG29_HUMAN,tr|G3XAN5|G3XAN5_HUMAN,tr|E5RHK2|E5RHK2_HUMAN,tr|E5RG56|E5RG56_HUMAN" 6 1899.801 1.38 35677 20785 2 1899.80336 950.9078 Aspartyl\asparaginyl beta-hydroxylase OS=Homo sapiens OX=9606 GN=ASPH PE=1 SV=3 3.5 3384.4 - 511738 - - - 1.2249 - 3.48 0.761 - 896.9 1 2 0 0.0023 18 0 0 0 6.29E+06 4.55E+06 - - - 7.7269 1 221125_WJC_METTL3_EV_vs_WT_F03.20790.20790.2 1.86E-09 14/34 R.LQEYGSIFTGAQDPGLQR[166.11].R "sp|Q9NQA3|WASH6_HUMAN,sp|A8K0Z3|WASH1_HUMAN,sp|C4AMC7|WASH3_HUMAN,sp|Q6VEQ5|WASH2_HUMAN,tr|A0A7I2YQU6|A0A7I2YQU6_HUMAN" 5 1988.9831 1.94 35682 20790 2 1988.981327 995.4988 WAS protein family homolog 6 OS=Homo sapiens OX=9606 GN=WASH6P PE=1 SV=3 4.37 3385 - 299360 - - - -0.904 - 3.021 0.602 - 319.7 1 2 0 -0.0018 18 0 0 0 6.36E+06 3.29E+06 - - - 6.2049 0.948 221125_WJC_METTL3_EV_vs_WT_F03.20794.20794.2 5.86 12-May R.FSGVPDR.F "sp|A0A075B6R9|KVD24_HUMAN,sp|A0A0C4DH68|KV224_HUMAN,sp|A2NJV5|KV229_HUMAN,sp|A0A075B6S2|KVD29_HUMAN,sp|A0A0A0MRZ7|KVD26_HUMAN" 5 776.3817 999 35686 20794 2 776.38289 389.1981 Probable non-functional immunoglobulin kappa variable 2D-24 OS=Homo sapiens OX=9606 GN=IGKV2D-24 PE=1 SV=1 5.84 3385.5 - 180526 - - - 1.5289 - 1.153 0.082 - 69.2 3 2 0 0.0012 7 0 0 0 1.93E+06 0.00E+00 - - - -0.1158 0.9996 221125_WJC_METTL3_EV_vs_WT_F03.20798.20798.3 1.98E-07 14/44 R.AR[166.11]FEELC[160.03]SDLFR[166.11].S "sp|P48741|HSP77_HUMAN,sp|P0DMV8|HS71A_HUMAN,sp|P0DMV9|HS71B_HUMAN,sp|P17066|HSP76_HUMAN,tr|V9GZ37|V9GZ37_HUMAN,tr|A0A0G2JIW1|A0A0G2JIW1_HUMAN" 6 1561.7462 0.09 35688 20798 3 1561.749741 521.5893 Putative heat shock 70 kDa protein 7 OS=Homo sapiens OX=9606 GN=HSPA7 PE=5 SV=2 4.68 3386.1 - 4.05E+06 - - - 2.2654 - 2.861 0.438 - 380.9 1 2 1 0.0035 12 0 0 0 1.90E+08 2.08E+09 - - - 6.336 1 221125_WJC_METTL3_EV_vs_WT_F03.20799.20799.3 3.69E-06 Dec-64 K.INLEAAELGEISDIHTK.L "sp|Q9UHD2|TBK1_HUMAN,tr|A0A7I2V646|A0A7I2V646_HUMAN,tr|A0A7I2V4Z2|A0A7I2V4Z2_HUMAN,tr|A0A494C079|A0A494C079_HUMAN,tr|A0A494C045|A0A494C045_HUMAN,tr|A0A494C1M6|A0A494C1M6_HUMAN,tr|A0A494C0A8|A0A494C0A8_HUMAN,tr|A0A7I2V4W4|A0A7I2V4W4_HUMAN,tr|A0A7I2V636|A0A7I2V636_HUMAN,tr|A0A7I2V463|A0A7I2V463_HUMAN,tr|A0A494C148|A0A494C148_HUMAN,tr|A0A494C0X2|A0A494C0X2_HUMAN,tr|A0A494C167|A0A494C167_HUMAN,tr|A0A7I2V5Y4|A0A7I2V5Y4_HUMAN,tr|A0A7I2V2F4|A0A7I2V2F4_HUMAN,tr|A0A494C0R4|A0A494C0R4_HUMAN,tr|A0A7I2V643|A0A7I2V643_HUMAN" 17 1851.9578 1.48 35689 20799 3 1851.957416 618.3265 Serine\threonine-protein kinase TBK1 OS=Homo sapiens OX=9606 GN=TBK1 PE=1 SV=1 4.4 3386.1 - 1.98E+06 - - - -0.2117 - 2.478 0.54 - 210.9 1 2 0 -0.0004 17 0 0 0 1.31E+07 8.84E+06 - - - 6.8529 0.9999 221125_WJC_METTL3_EV_vs_WT_F03.20800.20800.3 4.86E-06 13/56 K.FK[136.11]EVGEAFTILSDPK[136.11].K "sp|Q99615|DNJC7_HUMAN,tr|A0A6I8PRZ0|A0A6I8PRZ0_HUMAN,tr|A0A6I8PIK4|A0A6I8PIK4_HUMAN,tr|A0A6I8PS32|A0A6I8PS32_HUMAN,tr|A0A6I8PUD4|A0A6I8PUD4_HUMAN,tr|K7ER44|K7ER44_HUMAN,tr|A0A6I8PU73|A0A6I8PU73_HUMAN" 7 1695.9054 1.43 35690 20800 3 1695.90671 566.3091 DnaJ homolog subfamily C member 7 OS=Homo sapiens OX=9606 GN=DNAJC7 PE=1 SV=2 4.68 3386.2 - 1.27E+06 - - - 0.75 - 2.749 0.518 - 150.9 1 2 1 0.0013 15 0 0 0 2.58E+07 1.80E+07 - - - 6.9535 0.9999 221125_WJC_METTL3_EV_vs_WT_F03.20801.20801.3 1.57E-07 16/56 R.AGVAFFHLQDYDQAR.H "sp|Q8N5M4|TTC9C_HUMAN,tr|E9PKV8|E9PKV8_HUMAN,tr|H0YDR3|H0YDR3_HUMAN" 3 1736.8271 1.23 35691 20801 3 1736.833863 579.9496 Tetratricopeptide repeat protein 9C OS=Homo sapiens OX=9606 GN=TTC9C PE=1 SV=1 5.21 3386.3 - 1.25E+06 - - - 3.9123 - 3.221 0.515 - 534.9 1 2 0 0.0068 15 0 0 0 1.78E+07 1.44E+07 - - - 7.332 1 221125_WJC_METTL3_EV_vs_WT_F03.20802.20802.2 3.79E-14 20/34 K.VLAGETLSVNDPPDVLDR[166.11].Q "sp|Q12906|ILF3_HUMAN,tr|K7EQR9|K7EQR9_HUMAN,tr|K7EKJ9|K7EKJ9_HUMAN" 3 1918.9875 1.24 35692 20802 2 1918.991633 960.501 Interleukin enhancer-binding factor 3 OS=Homo sapiens OX=9606 GN=ILF3 PE=1 SV=3 3.84 3386.4 - 1.20E+06 - - - 2.1319 - 3.76 0.667 - 670.6 1 2 0 0.0041 18 0 0 0 2.83E+07 2.28E+07 - - - 7.2223 1 221125_WJC_METTL3_EV_vs_WT_F03.20804.20804.3 0.000162 16/52 K.SGPLFNFDVHDDVR[166.11].L "sp|Q14320|FA50A_HUMAN,tr|B0S8I6|B0S8I6_HUMAN" 2 1626.7666 0.71 35694 20804 3 1626.767428 543.2628 Protein FAM50A OS=Homo sapiens OX=9606 GN=FAM50A PE=1 SV=2 4.41 3386.6 - 1.15E+06 - - - 0.5151 - 3.072 0.505 - 329.2 1 2 0 0.0008 14 0 0 0 5.15E+06 7.24E+06 - - - 7.1526 1 221125_WJC_METTL3_EV_vs_WT_F03.20806.20806.2 2.43E-09 19/36 R.QAVLGAGLPISTPC[160.03]TTINK.V "sp|P24752|THIL_HUMAN,tr|A0A5F9ZHJ7|A0A5F9ZHJ7_HUMAN,tr|A0A5F9ZHH9|A0A5F9ZHH9_HUMAN,tr|A0A5F9ZHJ0|A0A5F9ZHJ0_HUMAN,tr|A0A5F9ZHL1|A0A5F9ZHL1_HUMAN,tr|H0YEL7|H0YEL7_HUMAN" 6 1940.0401 1.46 35696 20806 2 1940.040951 971.0273 "Acetyl-CoA acetyltransferase, mitochondrial OS=Homo sapiens OX=9606 GN=ACAT1 PE=1 SV=1" 8.22 3386.8 - 836676 - - - 0.4397 - 3.564 0.634 - 840.6 1 2 0 0.0009 19 0 0 0 6.13E+07 4.20E+07 - - - 6.848 1 221125_WJC_METTL3_EV_vs_WT_F03.20808.20808.2 8.07E-08 13/34 R.LQEYGSIFTGAQDPGLQR.R "sp|Q9NQA3|WASH6_HUMAN,sp|A8K0Z3|WASH1_HUMAN,sp|C4AMC7|WASH3_HUMAN,sp|Q6VEQ5|WASH2_HUMAN,tr|A0A7I2YQU6|A0A7I2YQU6_HUMAN" 5 1978.9749 1.94 35698 20808 2 1978.981572 990.4947 WAS protein family homolog 6 OS=Homo sapiens OX=9606 GN=WASH6P PE=1 SV=3 4.37 3387.1 - 713508 - - - 3.3942 - 2.772 0.598 - 252.1 1 2 0 0.0067 18 0 0 0 6.36E+06 3.29E+06 - - - 5.9624 1 221125_WJC_METTL3_EV_vs_WT_F03.20809.20809.2 4.80E-12 20/32 K.FDTGNLC[160.03]MVTGGANLGR.L sp|P62701|RS4X_HUMAN 1 1781.8189 0.9 35699 20809 2 1781.819801 891.9167 "40S ribosomal protein S4, X isoform OS=Homo sapiens OX=9606 GN=RPS4X PE=1 SV=2" 5.83 3387.2 - 632222 - - - 0.5118 - 3.702 0.662 - 1290.8 1 2 0 0.0009 17 0 0 0 1.86E+08 2.07E+08 - - - 7.1482 1 221125_WJC_METTL3_EV_vs_WT_F03.20810.20810.2 4.20E-09 18/34 K.IGNTSPLTTLPESSAFAK.G sp|P0CG40|SP9_HUMAN 1 1832.952 0.88 35700 20810 2 1832.955411 917.4833 Transcription factor Sp9 OS=Homo sapiens OX=9606 GN=SP9 PE=3 SV=1 6 3387.3 - 613939 - - - 1.8642 - 3.394 0.509 - 722.9 1 2 0 0.0034 18 0 0 0 9.06E+06 1.03E+07 - - - 5.8038 0.9992 221125_WJC_METTL3_EV_vs_WT_F03.20811.20811.2 2.56E-06 22-Dec R.LNVGGTYFLTTR[166.11].Q "sp|Q9NXV2|KCTD5_HUMAN,tr|H3BSS5|H3BSS5_HUMAN" 2 1350.7171 3.89 35701 20811 2 1350.722087 676.3658 BTB\POZ domain-containing protein KCTD5 OS=Homo sapiens OX=9606 GN=KCTD5 PE=1 SV=1 8.75 3387.5 - 498025 - - - 3.6766 - 2.438 0.509 - 494.3 1 2 0 0.005 12 0 0 0 3.86E+07 9.92E+06 - - - 5.1438 1 221125_WJC_METTL3_EV_vs_WT_F03.20812.20812.2 2.93E-09 19/36 R.QAVLGAGLPISTPC[160.03]TTINK[136.11].V "sp|P24752|THIL_HUMAN,tr|A0A5F9ZHJ7|A0A5F9ZHJ7_HUMAN,tr|A0A5F9ZHH9|A0A5F9ZHH9_HUMAN,tr|A0A5F9ZHJ0|A0A5F9ZHJ0_HUMAN,tr|A0A5F9ZHL1|A0A5F9ZHL1_HUMAN,tr|H0YEL7|H0YEL7_HUMAN" 6 1948.0543 1.46 35702 20812 2 1948.059852 975.0344 "Acetyl-CoA acetyltransferase, mitochondrial OS=Homo sapiens OX=9606 GN=ACAT1 PE=1 SV=1" 8.22 3387.6 - 489024 - - - 2.851 - 3.618 0.594 - 846.1 1 2 0 0.0056 19 0 0 0 6.13E+07 4.20E+07 - - - 6.588 1 221125_WJC_METTL3_EV_vs_WT_F03.20813.20813.2 7.94E-16 20/40 R.IPSAVGYQPTLATDMGTMQER.L "sp|P06576|ATPB_HUMAN,tr|F8W079|F8W079_HUMAN,tr|H0YI37|H0YI37_HUMAN,tr|F8W0P7|F8W0P7_HUMAN,tr|H0YH81|H0YH81_HUMAN" 5 2265.077 2.3 35703 20813 2 2265.07919 1133.5458 "ATP synthase subunit beta, mitochondrial OS=Homo sapiens OX=9606 GN=ATP5F1B PE=1 SV=3" 4.37 3387.7 - 346261 - - - 0.9872 - 4.014 0.744 - 738.6 1 2 0 0.0022 21 0 0 0 1.35E+07 5.86E+06 - - - 7.9523 0.9998 221125_WJC_METTL3_EV_vs_WT_F03.20817.20817.2 6.75E-07 22-Dec K.EFSPFGSITSAK.V "sp|Q13310|PABP4_HUMAN,tr|A0A7I2V5W9|A0A7I2V5W9_HUMAN,tr|H0YEU6|H0YEU6_HUMAN,tr|B1ANR0|B1ANR0_HUMAN,tr|A0A7I2V4L7|A0A7I2V4L7_HUMAN,tr|A0A7I2V598|A0A7I2V598_HUMAN,tr|H0Y5F5|H0Y5F5_HUMAN" 7 1269.6241 1.44 35706 20817 2 1269.625994 635.8193 Polyadenylate-binding protein 4 OS=Homo sapiens OX=9606 GN=PABPC4 PE=1 SV=1 6.1 3388.2 - 9.07E+06 - - - 1.4776 - 2.048 0.563 - 571 1 2 0 0.0019 12 0 0 0 8.50E+07 5.92E+07 - - - 5.0849 0.9993 221125_WJC_METTL3_EV_vs_WT_F03.20818.20818.2 3.66E-05 28-Oct R.ALTVPELTQQMFDSK[136.11].N "sp|Q9BVA1|TBB2B_HUMAN,sp|Q13885|TBB2A_HUMAN" 2 1714.8691 2 35707 20818 2 1714.87285 858.4418 Tubulin beta-2B chain OS=Homo sapiens OX=9606 GN=TUBB2B PE=1 SV=1 4.37 3388.3 - 995996 - - - 2.1733 - 1.936 0.42 - 184.2 1 2 0 0.0037 15 0 0 0 3.92E+07 1.96E+07 - - - 3.7661 1 221125_WJC_METTL3_EV_vs_WT_F03.20819.20819.3 1.06E-08 21/72 R.QAVLGAGLPISTPC[160.03]TTINK.V "sp|P24752|THIL_HUMAN,tr|A0A5F9ZHJ7|A0A5F9ZHJ7_HUMAN,tr|A0A5F9ZHH9|A0A5F9ZHH9_HUMAN,tr|A0A5F9ZHJ0|A0A5F9ZHJ0_HUMAN,tr|A0A5F9ZHL1|A0A5F9ZHL1_HUMAN,tr|H0YEL7|H0YEL7_HUMAN" 6 1940.0401 1.31 35708 20819 3 1940.043538 647.6873 "Acetyl-CoA acetyltransferase, mitochondrial OS=Homo sapiens OX=9606 GN=ACAT1 PE=1 SV=1" 8.22 3388.4 - 3.95E+06 - - - 1.7732 - 2.826 0.522 - 421.9 1 2 0 0.0034 19 0 0 0 1.12E+08 8.59E+07 - - - 6.9111 1 221125_WJC_METTL3_EV_vs_WT_F03.20820.20820.3 2.80E-07 19/72 R.QAVLGAGLPISTPC[160.03]TTINK[136.11].V "sp|P24752|THIL_HUMAN,tr|A0A5F9ZHJ7|A0A5F9ZHJ7_HUMAN,tr|A0A5F9ZHH9|A0A5F9ZHH9_HUMAN,tr|A0A5F9ZHJ0|A0A5F9ZHJ0_HUMAN,tr|A0A5F9ZHL1|A0A5F9ZHL1_HUMAN,tr|H0YEL7|H0YEL7_HUMAN" 6 1948.0543 1.3 35709 20820 3 1948.058369 650.3587 "Acetyl-CoA acetyltransferase, mitochondrial OS=Homo sapiens OX=9606 GN=ACAT1 PE=1 SV=1" 8.22 3388.4 - 3.26E+06 - - - 2.0898 - 3.254 0.525 - 402.3 1 2 0 0.0041 19 0 0 0 1.12E+08 8.59E+07 - - - 7.2908 1 221125_WJC_METTL3_EV_vs_WT_F03.20821.20821.3 2.96E-09 17/64 K.FDTGNLC[160.03]MVTGGANLGR[166.11].L sp|P62701|RS4X_HUMAN 1 1791.8272 1 35710 20821 3 1791.832414 598.283 "40S ribosomal protein S4, X isoform OS=Homo sapiens OX=9606 GN=RPS4X PE=1 SV=2" 5.83 3388.5 - 1.98E+06 - - - 2.9328 - 3.711 0.608 - 324.6 1 2 0 0.0053 17 0 0 0 6.66E+07 6.66E+07 - - - 8.6299 1 221125_WJC_METTL3_EV_vs_WT_F03.20823.20823.3 6.86E-08 14/64 K.FDTGNLC[160.03]MVTGGANLGR.L sp|P62701|RS4X_HUMAN 1 1781.8189 1 35712 20823 3 1781.821416 594.9469 "40S ribosomal protein S4, X isoform OS=Homo sapiens OX=9606 GN=RPS4X PE=1 SV=2" 5.83 3388.6 - 1.48E+06 - - - 1.4182 - 3.19 0.565 - 194.8 1 2 0 0.0025 17 0 0 0 6.66E+07 6.66E+07 - - - 7.7691 0.9997 221125_WJC_METTL3_EV_vs_WT_F03.20824.20824.2 2.90E-07 14/26 K.SFTASC[160.03]PVSAFVPK[136.11].E sp|Q6P587|FAHD1_HUMAN 1 1504.7476 0.76 35713 20824 2 1504.751573 753.3811 "Acylpyruvase FAHD1, mitochondrial OS=Homo sapiens OX=9606 GN=FAHD1 PE=1 SV=2" 7.94 3388.7 - 1.38E+06 - - - 2.6729 - 2.384 0.597 - 576.4 1 2 0 0.004 14 0 0 0 3.40E+07 4.46E+07 - - - 5.6293 0.9989 221125_WJC_METTL3_EV_vs_WT_F03.20825.20825.3 0.00276 14/68 R.LQEYGSIFTGAQDPGLQR[166.11].R "sp|Q9NQA3|WASH6_HUMAN,sp|A8K0Z3|WASH1_HUMAN,sp|C4AMC7|WASH3_HUMAN,sp|Q6VEQ5|WASH2_HUMAN,tr|A0A7I2YQU6|A0A7I2YQU6_HUMAN" 5 1988.9831 0.95 35714 20825 3 1988.981086 664.0017 WAS protein family homolog 6 OS=Homo sapiens OX=9606 GN=WASH6P PE=1 SV=3 4.37 3388.8 - 1.37E+06 - - - -1.0251 - 1.506 0.332 - 132 1 2 0 -0.002 18 0 0 0 1.44E+07 1.51E+07 - - - 3.2605 0.9999 221125_WJC_METTL3_EV_vs_WT_F03.20827.20827.3 4.02E-07 15/44 R.ARFEELC[160.03]SDLFR.S "sp|P48741|HSP77_HUMAN,sp|P0DMV8|HS71A_HUMAN,sp|P0DMV9|HS71B_HUMAN,sp|P17066|HSP76_HUMAN,tr|V9GZ37|V9GZ37_HUMAN,tr|A0A0G2JIW1|A0A0G2JIW1_HUMAN" 6 1541.7297 0.09 35716 20827 3 1541.73174 514.9172 Putative heat shock 70 kDa protein 7 OS=Homo sapiens OX=9606 GN=HSPA7 PE=5 SV=2 4.68 3389 - 1.13E+06 - - - 1.3472 - 2.875 0.541 - 391.4 1 2 1 0.0021 12 0 0 0 1.90E+08 2.08E+09 - - - 7.4983 0.9998 221125_WJC_METTL3_EV_vs_WT_F03.20829.20829.3 0.000371 Dec-64 R.ADIEVAC[160.03]YGYEGIDAVK[136.11].E "sp|P05198|IF2A_HUMAN,tr|H0YJS4|H0YJS4_HUMAN,tr|G3V4T5|G3V4T5_HUMAN" 3 1879.8753 0.3 35718 20829 3 1879.873437 627.6324 Eukaryotic translation initiation factor 2 subunit 1 OS=Homo sapiens OX=9606 GN=EIF2S1 PE=1 SV=3 3.92 3389.2 - 463889 - - - -1.0075 - 1.888 0.411 - 89.7 1 2 0 -0.0019 17 0 0 0 9.28E+05 3.06E+06 - - - 4.7272 1 221125_WJC_METTL3_EV_vs_WT_F03.20830.20830.2 2.16E-09 16/30 R.VGPQYQAVVPDFDPAK[136.11].L sp|Q9UKL0|RCOR1_HUMAN 1 1737.8817 2.57 35719 20830 2 1737.884443 869.9481 REST corepressor 1 OS=Homo sapiens OX=9606 GN=RCOR1 PE=1 SV=2 4.21 3389.3 - 370912 - - - 1.5576 - 2.69 0.626 - 676.4 1 2 0 0.0027 16 0 0 0 3.09E+07 1.20E+07 - - - 6.0966 1 221125_WJC_METTL3_EV_vs_WT_F03.20834.20834.2 7.51E-06 14/26 K.SFTASC[160.03]PVSAFVPK.E sp|Q6P587|FAHD1_HUMAN 1 1496.7334 0.97 35722 20834 2 1496.734598 749.374 "Acylpyruvase FAHD1, mitochondrial OS=Homo sapiens OX=9606 GN=FAHD1 PE=1 SV=2" 7.94 3389.8 - 1.70E+06 - - - 0.8331 - 2.549 0.628 - 591.2 1 2 0 0.0012 14 0 0 0 1.38E+07 1.42E+07 - - - 6.0271 1 221125_WJC_METTL3_EV_vs_WT_F03.20836.20836.2 2.99E-13 19/32 K.FDTGNLC[160.03]MVTGGANLGR[166.11].L sp|P62701|RS4X_HUMAN 1 1791.8272 0.9 35723 20836 2 1791.82781 896.9209 "40S ribosomal protein S4, X isoform OS=Homo sapiens OX=9606 GN=RPS4X PE=1 SV=2" 5.83 3390 - 1.07E+07 - - - 0.3633 - 3.618 0.695 - 1116.9 1 2 0 0.0007 17 0 0 0 1.86E+08 2.07E+08 - - - 7.3356 0.9973 221125_WJC_METTL3_EV_vs_WT_F03.20837.20837.2 1.62E-05 13/22 R.AR[166.11]FEELC[160.03]SDLFR[166.11].S "sp|P48741|HSP77_HUMAN,sp|P0DMV8|HS71A_HUMAN,sp|P0DMV9|HS71B_HUMAN,sp|P17066|HSP76_HUMAN,tr|V9GZ37|V9GZ37_HUMAN,tr|A0A0G2JIW1|A0A0G2JIW1_HUMAN" 6 1561.7462 0.09 35724 20837 2 1561.7436 781.8804 Putative heat shock 70 kDa protein 7 OS=Homo sapiens OX=9606 GN=HSPA7 PE=5 SV=2 4.68 3390.1 - 8.03E+06 - - - -1.6667 - 2.226 0.472 - 266.6 1 2 1 -0.0026 12 0 0 0 3.83E+07 4.42E+08 - - - 4.6319 0.9999 221125_WJC_METTL3_EV_vs_WT_F03.20839.20839.2 1.75E-06 22-Dec K.EFSPFGSITSAK[136.11].V "sp|Q13310|PABP4_HUMAN,tr|A0A7I2V5W9|A0A7I2V5W9_HUMAN,tr|H0YEU6|H0YEU6_HUMAN,tr|B1ANR0|B1ANR0_HUMAN,tr|A0A7I2V4L7|A0A7I2V4L7_HUMAN,tr|A0A7I2V598|A0A7I2V598_HUMAN,tr|H0Y5F5|H0Y5F5_HUMAN" 7 1277.6383 1.44 35726 20839 2 1277.639296 639.8264 Polyadenylate-binding protein 4 OS=Homo sapiens OX=9606 GN=PABPC4 PE=1 SV=1 6.1 3390.1 - 7.89E+06 - - - 0.7655 - 2.108 0.567 - 577.6 1 2 0 0.001 12 0 0 0 8.50E+07 5.92E+07 - - - 5.1907 1 221125_WJC_METTL3_EV_vs_WT_F03.20840.20840.2 4.37E-10 20/36 R.ILSAENIPNLPPGGGLAGK.R "sp|O75688|PPM1B_HUMAN,tr|B8ZZF0|B8ZZF0_HUMAN,tr|A0A3B3IS24|A0A3B3IS24_HUMAN,tr|C9JIR6|C9JIR6_HUMAN" 4 1817.0047 3.81 35727 20840 2 1817.005123 909.5096 Protein phosphatase 1B OS=Homo sapiens OX=9606 GN=PPM1B PE=1 SV=1 6 3390.2 - 3.99E+06 - - - 0.2334 - 3.354 0.575 - 689.7 1 2 0 0.0004 19 0 0 0 1.02E+08 2.67E+07 - - - 6.263 0.9997 221125_WJC_METTL3_EV_vs_WT_F03.20841.20841.3 0.00516 13/56 R.AGVAFFHLQDYDQAR[166.11].H "sp|Q8N5M4|TTC9C_HUMAN,tr|E9PKV8|E9PKV8_HUMAN,tr|H0YDR3|H0YDR3_HUMAN" 3 1746.8353 1.77 35728 20841 3 1746.837154 583.2857 Tetratricopeptide repeat protein 9C OS=Homo sapiens OX=9606 GN=TTC9C PE=1 SV=1 5.21 3390.2 - 2.47E+06 - - - 1.0396 - 2.297 0.333 - 192.8 1 2 0 0.0018 15 0 0 0 2.62E+07 1.47E+07 - - - 4.4221 1 221125_WJC_METTL3_EV_vs_WT_F03.20842.20842.3 1.28E-09 16/48 K.LHNMIVDLDNVVK[136.11].K "sp|Q16891|MIC60_HUMAN,tr|B9A067|B9A067_HUMAN,tr|C9J406|C9J406_HUMAN,tr|H7C463|H7C463_HUMAN" 4 1516.8163 1.34 35729 20842 3 1516.817772 506.6127 MICOS complex subunit MIC60 OS=Homo sapiens OX=9606 GN=IMMT PE=1 SV=1 5.21 3390.3 - 1.74E+06 - - - 0.9711 - 2.834 0.623 - 503.3 1 2 0 0.0015 13 0 0 0 1.82E+08 1.35E+08 - - - 8.3097 1 221125_WJC_METTL3_EV_vs_WT_F03.20843.20843.2 1.82E-10 16/28 R.SMGETESGDAFLDLK.K "sp|Q9NRA8|4ET_HUMAN,tr|B1AKL6|B1AKL6_HUMAN,tr|B1AKL5|B1AKL5_HUMAN,tr|B1AKL4|B1AKL4_HUMAN" 4 1598.7134 1.48 35730 20843 2 1598.715181 800.364 Eukaryotic translation initiation factor 4E transporter OS=Homo sapiens OX=9606 GN=EIF4ENIF1 PE=1 SV=2 3.92 3390.4 - 1.47E+06 - - - 1.1121 - 2.935 0.668 - 879.6 1 2 0 0.0018 15 0 0 0 3.12E+07 2.11E+07 - - - 6.6214 0.9999 221125_WJC_METTL3_EV_vs_WT_F03.20845.20845.2 4.87E-09 24-Nov K.VNFPENGFLSPDK[136.11].L sp|P31689|DNJA1_HUMAN 1 1470.7234 0.52 35732 20845 2 1470.721601 736.369 DnaJ homolog subfamily A member 1 OS=Homo sapiens OX=9606 GN=DNAJA1 PE=1 SV=2 4.37 3390.7 - 1.22E+06 - - - -1.2538 - 2.267 0.613 - 325.1 1 2 0 -0.0018 13 0 0 0 3.88E+07 7.41E+07 - - - 5.6686 0.9948 221125_WJC_METTL3_EV_vs_WT_F03.20846.20846.3 0.0875 Nov-56 K.FKEVGEAFTILSDPK.K "sp|Q99615|DNJC7_HUMAN,tr|A0A6I8PRZ0|A0A6I8PRZ0_HUMAN,tr|A0A6I8PIK4|A0A6I8PIK4_HUMAN,tr|A0A6I8PS32|A0A6I8PS32_HUMAN,tr|A0A6I8PUD4|A0A6I8PUD4_HUMAN,tr|K7ER44|K7ER44_HUMAN,tr|A0A6I8PU73|A0A6I8PU73_HUMAN" 7 1679.877 0.58 35733 20846 3 1679.878037 560.9663 DnaJ homolog subfamily C member 7 OS=Homo sapiens OX=9606 GN=DNAJC7 PE=1 SV=2 4.68 3390.8 - 1.10E+06 - - - 0.5947 - 1.713 0.294 - 99.9 1 2 1 0.001 15 0 0 0 8.54E+06 1.47E+07 - - - 3.222 0.9999 221125_WJC_METTL3_EV_vs_WT_F03.20847.20847.3 5.18E-05 17/72 K.VLAPQISFAPEIASEEER[166.11]K[136.11].G "sp|P16083|NQO2_HUMAN,tr|Q5TD07|Q5TD07_HUMAN" 2 2131.128 1.53 35734 20847 3 2131.1339 711.3833 Ribosyldihydronicotinamide dehydrogenase [quinone] OS=Homo sapiens OX=9606 GN=NQO2 PE=1 SV=5 4.49 3390.9 - 841402 - - - 2.7661 - 3.324 0.505 - 332.7 1 2 0 0.0059 19 0 0 0 8.29E+06 5.44E+06 - - - 7.1197 1 221125_WJC_METTL3_EV_vs_WT_F03.20848.20848.3 4.37E-13 22/72 K.VLAPQISFAPEIASEEERK.G "sp|P16083|NQO2_HUMAN,tr|Q5TD07|Q5TD07_HUMAN" 2 2113.1055 1.32 35735 20848 3 2113.107045 705.3758 Ribosyldihydronicotinamide dehydrogenase [quinone] OS=Homo sapiens OX=9606 GN=NQO2 PE=1 SV=5 4.49 3391 - 799532 - - - 0.7146 - 4.037 0.66 - 623.6 1 2 0 0.0015 19 0 0 0 7.19E+06 5.44E+06 - - - 9.3264 0.9982 221125_WJC_METTL3_EV_vs_WT_F03.20849.20849.3 2.29E-05 14/44 R.ARFEELC[160.03]SDLFR[166.11].S "sp|P48741|HSP77_HUMAN,sp|P0DMV8|HS71A_HUMAN,sp|P0DMV9|HS71B_HUMAN,sp|P17066|HSP76_HUMAN,tr|V9GZ37|V9GZ37_HUMAN,tr|A0A0G2JIW1|A0A0G2JIW1_HUMAN" 6 1551.7379 - 35736 20849 3 1551.743738 518.2533 Putative heat shock 70 kDa protein 7 OS=Homo sapiens OX=9606 GN=HSPA7 PE=5 SV=2 4.68 3391.2 - 730583 - - - 3.741 - 2.351 0.432 - 338.1 1 2 1 0.0058 12 0 0 0 - - - - - 5.7243 1 221125_WJC_METTL3_EV_vs_WT_F03.20850.20850.2 2.49E-06 17/32 R.ADIEVAC[160.03]YGYEGIDAVK.E "sp|P05198|IF2A_HUMAN,tr|H0YJS4|H0YJS4_HUMAN,tr|G3V4T5|G3V4T5_HUMAN" 3 1871.8611 0.29 35737 20850 2 1871.863445 936.9378 Eukaryotic translation initiation factor 2 subunit 1 OS=Homo sapiens OX=9606 GN=EIF2S1 PE=1 SV=3 3.92 3391.3 - 589903 - - - 1.2362 - 3.477 0.639 - 1169.2 1 2 0 0.0023 17 0 0 0 3.43E+06 1.18E+07 - - - 6.8237 0.9999 221125_WJC_METTL3_EV_vs_WT_F03.20851.20851.2 1.19E-05 24-Oct K.VNFPENGFLSPDK.L sp|P31689|DNJA1_HUMAN 1 1462.7092 0.52 35738 20851 2 1462.709629 732.3619 DnaJ homolog subfamily A member 1 OS=Homo sapiens OX=9606 GN=DNAJA1 PE=1 SV=2 4.37 3391.4 - 502532 - - - 0.2625 - 2.138 0.52 - 243.2 1 2 0 0.0004 13 0 0 0 3.88E+07 7.41E+07 - - - 4.8318 0.9999 221125_WJC_METTL3_EV_vs_WT_F03.20853.20853.3 3.96E-05 13/40 K.HLLGVEDLLQK[136.11].H "sp|Q01082|SPTB2_HUMAN,tr|A0A087WUZ3|A0A087WUZ3_HUMAN,tr|F8W6C1|F8W6C1_HUMAN" 3 1271.7329 1.47 35740 20853 3 1271.733118 424.9182 "Spectrin beta chain, non-erythrocytic 1 OS=Homo sapiens OX=9606 GN=SPTBN1 PE=1 SV=2" 5.32 3391.7 - 472703 - - - 0.1816 - 2.495 0.406 - 386.4 1 2 0 0.0002 11 0 0 0 1.19E+07 8.10E+06 - - - 5.6638 0.9998 221125_WJC_METTL3_EV_vs_WT_F03.20855.20855.3 1.08E-06 14/40 K.HLLGVEDLLQK.H "sp|Q01082|SPTB2_HUMAN,tr|A0A087WUZ3|A0A087WUZ3_HUMAN,tr|F8W6C1|F8W6C1_HUMAN" 3 1263.7187 1.47 35742 20855 3 1263.717746 422.2468 "Spectrin beta chain, non-erythrocytic 1 OS=Homo sapiens OX=9606 GN=SPTBN1 PE=1 SV=2" 5.32 3391.9 - 444800 - - - -0.7446 - 2.622 0.312 - 413.3 1 2 0 -0.0009 11 0 0 0 1.19E+07 8.10E+06 - - - 4.7566 1 221125_WJC_METTL3_EV_vs_WT_F03.20857.20857.3 5.02E-07 18/72 R.ILSAENIPNLPPGGGLAGK.R "sp|O75688|PPM1B_HUMAN,tr|B8ZZF0|B8ZZF0_HUMAN,tr|A0A3B3IS24|A0A3B3IS24_HUMAN,tr|C9JIR6|C9JIR6_HUMAN" 4 1817.0047 4.64 35743 20857 3 1817.006805 606.6755 Protein phosphatase 1B OS=Homo sapiens OX=9606 GN=PPM1B PE=1 SV=1 6 3392.2 - 6.67E+06 - - - 1.1591 - 2.633 0.559 - 297.6 1 2 0 0.0021 19 0 0 0 9.68E+07 2.09E+07 - - - 7.1502 1 221125_WJC_METTL3_EV_vs_WT_F03.20858.20858.2 1.55E-08 30-Dec R.STQPLTFTTATFAATK.F sp|P50616|TOB1_HUMAN 1 1684.8672 -1 35744 20858 2 1684.874057 843.4409 Protein Tob1 OS=Homo sapiens OX=9606 GN=TOB1 PE=1 SV=1 8.47 3392.3 - 636989 - - - 4.0686 - 2.552 0.593 - 395.5 1 2 0 0.0069 16 0 0 0 0.00E+00 0.00E+00 - - - 5.7221 1 221125_WJC_METTL3_EV_vs_WT_F03.20859.20859.3 7.39E-11 22/80 R.IPSAVGYQPTLATDMGTMQER[166.11].L "sp|P06576|ATPB_HUMAN,tr|F8W079|F8W079_HUMAN,tr|H0YI37|H0YI37_HUMAN,tr|F8W0P7|F8W0P7_HUMAN,tr|H0YH81|H0YH81_HUMAN" 5 2275.0852 1.86 35745 20859 3 2275.083613 759.369 "ATP synthase subunit beta, mitochondrial OS=Homo sapiens OX=9606 GN=ATP5F1B PE=1 SV=3" 4.37 3392.4 - 4.60E+06 - - - -0.7081 - 4.347 0.692 - 618.6 1 2 0 -0.0016 21 0 0 0 8.48E+07 4.55E+07 - - - 9.7777 1 221125_WJC_METTL3_EV_vs_WT_F03.20860.20860.2 2.67E-05 22-Sep K.SNTLPISLQSIR[166.11].S "sp|P42704|LPPRC_HUMAN,tr|A0A804HI14|A0A804HI14_HUMAN,tr|A0A804HL40|A0A804HL40_HUMAN,tr|A0A804HKJ0|A0A804HKJ0_HUMAN,tr|A0A804HKR3|A0A804HKR3_HUMAN,tr|A0A804HIN4|A0A804HIN4_HUMAN,tr|A0A804HLG8|A0A804HLG8_HUMAN,tr|A0A804HIV5|A0A804HIV5_HUMAN,tr|A0A804HHY9|A0A804HHY9_HUMAN,tr|A0A804HJH8|A0A804HJH8_HUMAN,tr|B8ZZ38|B8ZZ38_HUMAN,tr|A0A804HI40|A0A804HI40_HUMAN,tr|A0A804HJZ1|A0A804HJZ1_HUMAN,tr|C9JCA9|C9JCA9_HUMAN,tr|A0A804HIQ7|A0A804HIQ7_HUMAN,tr|A0A804HK30|A0A804HK30_HUMAN,tr|A0A804HKI2|A0A804HKI2_HUMAN,tr|A0A804HJI0|A0A804HJI0_HUMAN,tr|A0A804HIG4|A0A804HIG4_HUMAN,tr|A0A804HK02|A0A804HK02_HUMAN" 20 1337.7542 0.73 35746 20860 2 1337.753078 669.8844 "Leucine-rich PPR motif-containing protein, mitochondrial OS=Homo sapiens OX=9606 GN=LRPPRC PE=1 SV=3" 9.47 3392.4 - 4.25E+06 - - - -0.8649 - 2.374 0.607 - 202.6 1 2 0 -0.0012 12 0 0 0 2.65E+07 3.61E+07 - - - 5.7988 0.9999 221125_WJC_METTL3_EV_vs_WT_F03.20861.20861.2 1.17E-07 22-Oct K.SNTLPISLQSIR.S "sp|P42704|LPPRC_HUMAN,tr|A0A804HI14|A0A804HI14_HUMAN,tr|A0A804HL40|A0A804HL40_HUMAN,tr|A0A804HKJ0|A0A804HKJ0_HUMAN,tr|A0A804HKR3|A0A804HKR3_HUMAN,tr|A0A804HIN4|A0A804HIN4_HUMAN,tr|A0A804HLG8|A0A804HLG8_HUMAN,tr|A0A804HIV5|A0A804HIV5_HUMAN,tr|A0A804HHY9|A0A804HHY9_HUMAN,tr|A0A804HJH8|A0A804HJH8_HUMAN,tr|B8ZZ38|B8ZZ38_HUMAN,tr|A0A804HI40|A0A804HI40_HUMAN,tr|A0A804HJZ1|A0A804HJZ1_HUMAN,tr|C9JCA9|C9JCA9_HUMAN,tr|A0A804HIQ7|A0A804HIQ7_HUMAN,tr|A0A804HK30|A0A804HK30_HUMAN,tr|A0A804HKI2|A0A804HKI2_HUMAN,tr|A0A804HJI0|A0A804HJI0_HUMAN,tr|A0A804HIG4|A0A804HIG4_HUMAN,tr|A0A804HK02|A0A804HK02_HUMAN" 20 1327.746 0.73 35747 20861 2 1327.745429 664.8803 "Leucine-rich PPR motif-containing protein, mitochondrial OS=Homo sapiens OX=9606 GN=LRPPRC PE=1 SV=3" 9.47 3392.5 - 3.30E+06 - - - -0.4037 - 2.09 0.571 - 242.5 1 2 0 -0.0005 12 0 0 0 2.65E+07 3.61E+07 - - - 5.1978 0.9997 221125_WJC_METTL3_EV_vs_WT_F03.20862.20862.3 0.00128 Nov-60 K.AFAHITGGGLLENIPR.V sp|P22102|PUR2_HUMAN 1 1664.8998 1.21 35748 20862 3 1664.897562 555.9739 Trifunctional purine biosynthetic protein adenosine-3 OS=Homo sapiens OX=9606 GN=GART PE=1 SV=1 6.79 3392.5 - 2.29E+06 - - - -1.3676 - 2.38 0.337 - 161.7 1 2 0 -0.0023 16 0 0 0 3.14E+07 2.60E+07 - - - 4.5214 1 221125_WJC_METTL3_EV_vs_WT_F03.20863.20863.2 1.34E-08 15/26 R.SYLEFSEDSVQVPR.N sp|P51116|FXR2_HUMAN 1 1654.7839 1.47 35749 20863 2 1654.779795 828.3992 Fragile X mental retardation syndrome-related protein 2 OS=Homo sapiens OX=9606 GN=FXR2 PE=1 SV=2 4.14 3392.6 - 1.92E+06 - - - -2.4601 - 3.1 0.618 - 784 1 2 0 -0.0041 14 0 0 0 6.93E+07 4.70E+07 - - - 6.4435 1 221125_WJC_METTL3_EV_vs_WT_F03.20864.20864.3 6.70E-13 22/76 S.SLGGAMIDGQSAFANETLNK.A "sp|Q9Y5A9|YTHD2_HUMAN,tr|S4R3J8|S4R3J8_HUMAN,tr|S4R3V3|S4R3V3_HUMAN" 3 2022.9681 2.57 35750 20864 3 2022.968291 675.33 YTH domain-containing family protein 2 OS=Homo sapiens OX=9606 GN=YTHDF2 PE=1 SV=2 4.37 3392.7 - 1.54E+06 - - - 0.1167 - 3.631 0.677 - 406.5 1 1 0 0.0002 20 0 0 0 1.34E+07 5.20E+06 - - - 9.2162 1 221125_WJC_METTL3_EV_vs_WT_F03.20866.20866.2 2.09E-07 16/34 K.IGNTSPLTTLPESSAFAK[136.11].G sp|P0CG40|SP9_HUMAN 1 1840.9662 0.88 35752 20866 2 1840.962584 921.4904 Transcription factor Sp9 OS=Homo sapiens OX=9606 GN=SP9 PE=3 SV=1 6 3393 - 1.18E+06 - - - -1.9609 - 2.885 0.556 - 528.6 1 2 0 -0.0036 18 0 0 0 9.06E+06 1.03E+07 - - - 5.7514 1 221125_WJC_METTL3_EV_vs_WT_F03.20868.20868.2 1.14E-14 17/34 K.QQLSAEELDAQLDAYNAR[166.11].M "sp|Q86V81|THOC4_HUMAN,tr|E9PB61|E9PB61_HUMAN" 2 2043.9737 0.82 35754 20868 2 2043.973504 1022.9941 THO complex subunit 4 OS=Homo sapiens OX=9606 GN=ALYREF PE=1 SV=3 3.92 3393.2 - 831088 - - - -0.0876 - 3.886 0.722 - 1102.8 1 2 0 -0.0002 18 0 0 0 2.29E+07 2.78E+07 - - - 7.7108 0.9973 221125_WJC_METTL3_EV_vs_WT_F03.20870.20870.2 0.211 16-Jul R.LSNIFVIGK.G sp|P62701|RS4X_HUMAN 1 989.591 1.2 35756 20870 2 989.590671 495.8028 "40S ribosomal protein S4, X isoform OS=Homo sapiens OX=9606 GN=RPS4X PE=1 SV=2" 8.75 3393.5 - 740994 - - - -0.2991 - 1.316 0.232 - 99.5 1 2 0 -0.0003 9 0 0 0 4.32E+06 3.61E+06 - - - 1.5489 1 221125_WJC_METTL3_EV_vs_WT_F03.20871.20871.2 2.16E-12 15/38 S.SLGGAMIDGQSAFANETLNK.A "sp|Q9Y5A9|YTHD2_HUMAN,tr|S4R3J8|S4R3J8_HUMAN,tr|S4R3V3|S4R3V3_HUMAN" 3 2022.9681 2.58 35757 20871 2 2022.966176 1012.4913 YTH domain-containing family protein 2 OS=Homo sapiens OX=9606 GN=YTHDF2 PE=1 SV=2 4.37 3393.6 - 570653 - - - -0.9288 - 3.375 0.662 - 625.8 1 1 0 -0.0019 20 0 0 0 4.57E+06 1.77E+06 - - - 6.9205 0.9927 221125_WJC_METTL3_EV_vs_WT_F03.20875.20875.2 0.000221 15/26 N.AVITVPAYFNDSQR.Q "sp|P38646|GRP75_HUMAN,sp|P54652|HSP72_HUMAN,sp|P0DMV8|HS71A_HUMAN,sp|P34931|HS71L_HUMAN,sp|P0DMV9|HS71B_HUMAN,sp|P17066|HSP76_HUMAN,tr|H0Y8K0|H0Y8K0_HUMAN,tr|A0A7I2V2S7|A0A7I2V2S7_HUMAN,tr|A0A7I2V2G2|A0A7I2V2G2_HUMAN,tr|Q53FA3|Q53FA3_HUMAN,tr|A0A7I2V3F7|A0A7I2V3F7_HUMAN,tr|A0A7I2YQB2|A0A7I2YQB2_HUMAN,tr|A0A0G2JIW1|A0A0G2JIW1_HUMAN,tr|D6RCD7|D6RCD7_HUMAN" 14 1579.7995 0.11 35760 20875 2 1579.80129 790.907 "Stress-70 protein, mitochondrial OS=Homo sapiens OX=9606 GN=HSPA9 PE=1 SV=2" 5.88 3394.1 - 2.83E+06 - - - 1.1603 - 2.419 0.589 - 472.6 1 1 0 0.0018 14 0 0 0 2.92E+07 2.69E+08 - - - 5.6075 1 221125_WJC_METTL3_EV_vs_WT_F03.20877.20877.3 1.91E-09 19/80 R.IPSAVGYQPTLATDMGTMQER.L "sp|P06576|ATPB_HUMAN,tr|F8W079|F8W079_HUMAN,tr|H0YI37|H0YI37_HUMAN,tr|F8W0P7|F8W0P7_HUMAN,tr|H0YH81|H0YH81_HUMAN" 5 2265.077 1.86 35761 20877 3 2265.075147 756.0329 "ATP synthase subunit beta, mitochondrial OS=Homo sapiens OX=9606 GN=ATP5F1B PE=1 SV=3" 4.37 3394.3 - 6.00E+06 - - - -0.7978 - 3.188 0.653 - 211.5 1 2 0 -0.0018 21 0 0 0 8.48E+07 4.55E+07 - - - 8.5994 1 221125_WJC_METTL3_EV_vs_WT_F03.20878.20878.3 3.16E-08 19/72 R.FGVPVIADGGIQNVGHIAK[136.11].A "sp|P12268|IMDH2_HUMAN,tr|A0A7I2YQK5|A0A7I2YQK5_HUMAN,tr|H0Y4R1|H0Y4R1_HUMAN,tr|A0A7I2V2T3|A0A7I2V2T3_HUMAN,tr|E7ETK5|E7ETK5_HUMAN" 5 1899.0458 1.04 35762 20878 3 1899.043638 634.0225 Inosine-5'-monophosphate dehydrogenase 2 OS=Homo sapiens OX=9606 GN=IMPDH2 PE=1 SV=2 6.74 3394.3 - 5.37E+06 - - - -1.129 - 3.261 0.616 - 314.6 1 2 0 -0.0021 19 0 0 0 9.76E+07 9.38E+07 - - - 8.3112 1 221125_WJC_METTL3_EV_vs_WT_F03.20879.20879.3 3.60E-12 21/76 K.IIK[136.11]PVLTQESATYIAEEYSR[166.11].L "sp|P25205|MCM3_HUMAN,tr|Q7Z6P5|Q7Z6P5_HUMAN,tr|J3KQ69|J3KQ69_HUMAN,tr|A0A499FHX9|A0A499FHX9_HUMAN" 4 2328.2332 0.56 35763 20879 3 2328.230258 777.085 DNA replication licensing factor MCM3 OS=Homo sapiens OX=9606 GN=MCM3 PE=1 SV=3 4.79 3394.4 - 5.07E+06 - - - -1.2628 - 3.727 0.674 - 532.2 1 2 0 -0.0029 20 0 0 0 5.29E+07 9.38E+07 - - - 9.2453 1 221125_WJC_METTL3_EV_vs_WT_F03.20880.20880.3 8.42E-10 20/68 K.QQLSAEELDAQLDAYNAR.M "sp|Q86V81|THOC4_HUMAN,tr|E9PB61|E9PB61_HUMAN" 2 2033.9654 0.72 35764 20880 3 2033.96872 678.9957 THO complex subunit 4 OS=Homo sapiens OX=9606 GN=ALYREF PE=1 SV=3 3.92 3394.4 - 4.45E+06 - - - 1.6259 - 4.106 0.631 - 491 1 2 0 0.0033 18 0 0 0 5.45E+07 7.54E+07 - - - 9.0913 1 221125_WJC_METTL3_EV_vs_WT_F03.20881.20881.3 2.46E-11 17/76 K.IIKPVLTQESATYIAEEYSR.L "sp|P25205|MCM3_HUMAN,tr|Q7Z6P5|Q7Z6P5_HUMAN,tr|J3KQ69|J3KQ69_HUMAN,tr|A0A499FHX9|A0A499FHX9_HUMAN" 4 2310.2107 0.56 35765 20881 3 2310.213534 771.0775 DNA replication licensing factor MCM3 OS=Homo sapiens OX=9606 GN=MCM3 PE=1 SV=3 4.79 3394.5 - 3.71E+06 - - - 1.2146 - 2.794 0.607 - 110.1 1 2 0 0.0028 20 0 0 0 5.29E+07 9.38E+07 - - - 7.7993 1 221125_WJC_METTL3_EV_vs_WT_F03.20882.20882.2 1.37E-08 14/26 R.SYLEFSEDSVQVPR[166.11].N sp|P51116|FXR2_HUMAN 1 1664.7921 1.47 35766 20882 2 1664.789631 833.4033 Fragile X mental retardation syndrome-related protein 2 OS=Homo sapiens OX=9606 GN=FXR2 PE=1 SV=2 4.14 3394.5 - 3.17E+06 - - - -1.5047 - 2.996 0.667 - 737.3 1 2 0 -0.0025 14 0 0 0 6.93E+07 4.70E+07 - - - 6.7202 0.9996 221125_WJC_METTL3_EV_vs_WT_F03.20883.20883.2 0.000292 13/22 K.EFSPFGTITSAK.V "sp|P11940|PABP1_HUMAN,tr|A0A7I2YQE4|A0A7I2YQE4_HUMAN,tr|A0A7I2V649|A0A7I2V649_HUMAN,tr|H0YB86|H0YB86_HUMAN,tr|H0YAR2|H0YAR2_HUMAN,tr|E7ERJ7|E7ERJ7_HUMAN,tr|A0A7I2YQ88|A0A7I2YQ88_HUMAN,tr|A0A087WTT1|A0A087WTT1_HUMAN,tr|H0YAP2|H0YAP2_HUMAN,tr|A0A7I2V4N4|A0A7I2V4N4_HUMAN,tr|E7EQV3|E7EQV3_HUMAN" 11 1283.6398 1.35 35767 20883 2 1283.638796 642.8272 Polyadenylate-binding protein 1 OS=Homo sapiens OX=9606 GN=PABPC1 PE=1 SV=2 6.1 3394.6 - 2.50E+06 - - - -0.7572 - 1.677 0.387 - 260.8 1 2 0 -0.001 12 0 0 0 1.11E+08 8.19E+07 - - - 3.2594 1 221125_WJC_METTL3_EV_vs_WT_F03.20884.20884.2 8.86E-09 20/30 R.VGPQYQAVVPDFDPAK.L sp|Q9UKL0|RCOR1_HUMAN 1 1729.8675 2.57 35768 20884 2 1729.870571 865.941 REST corepressor 1 OS=Homo sapiens OX=9606 GN=RCOR1 PE=1 SV=2 4.21 3394.7 - 1.79E+06 - - - 1.7545 - 2.977 0.629 - 1232.6 1 2 0 0.003 16 0 0 0 3.09E+07 1.20E+07 - - - 6.3679 0.9999 221125_WJC_METTL3_EV_vs_WT_F03.20885.20885.3 7.24E-09 13/52 R.SYLEFSEDSVQVPR.N sp|P51116|FXR2_HUMAN 1 1654.7839 1.63 35769 20885 3 1654.77829 552.6019 Fragile X mental retardation syndrome-related protein 2 OS=Homo sapiens OX=9606 GN=FXR2 PE=1 SV=2 4.14 3394.8 - 1.68E+06 - - - -3.3696 - 2.492 0.566 - 188.2 1 2 0 -0.0056 14 0 0 0 2.02E+07 1.24E+07 - - - 7.2753 0.9998 221125_WJC_METTL3_EV_vs_WT_F03.20886.20886.2 0.000119 28-Nov K.NAVITVPAYFNDSQR.Q "sp|P38646|GRP75_HUMAN,sp|P0DMV8|HS71A_HUMAN,sp|P34931|HS71L_HUMAN,sp|P0DMV9|HS71B_HUMAN,tr|H0Y8K0|H0Y8K0_HUMAN,tr|A0A7I2V2S7|A0A7I2V2S7_HUMAN,tr|A0A7I2V2G2|A0A7I2V2G2_HUMAN,tr|Q53FA3|Q53FA3_HUMAN,tr|A0A7I2V3F7|A0A7I2V3F7_HUMAN,tr|A0A7I2YQB2|A0A7I2YQB2_HUMAN,tr|A0A0G2JIW1|A0A0G2JIW1_HUMAN,tr|D6RCD7|D6RCD7_HUMAN" 12 1693.8424 0.37 35770 20886 2 1693.84275 847.9285 "Stress-70 protein, mitochondrial OS=Homo sapiens OX=9606 GN=HSPA9 PE=1 SV=2" 5.84 3395 - 1.30E+06 - - - 0.2161 - 2.051 0.458 - 199.1 1 2 0 0.0004 15 0 0 0 7.95E+07 2.13E+08 - - - 4.1897 0.9995 221125_WJC_METTL3_EV_vs_WT_F03.20888.20888.2 5.40E-05 24-Dec K.GGSFQLNELQGLK.S "sp|P02788|TRFL_HUMAN,tr|C9JCF5|C9JCF5_HUMAN,tr|E7EQB2|E7EQB2_HUMAN,tr|E7ER44|E7ER44_HUMAN" 4 1389.7252 999 35772 20888 2 1389.727535 695.8699 Lactotransferrin OS=Homo sapiens OX=9606 GN=LTF PE=1 SV=6 6 3395.2 - 910267 - - - 1.6593 - 2.248 0.34 - 351.4 1 2 0 0.0023 13 0 0 0 8.63E+06 0.00E+00 - - - 3.6305 1 221125_WJC_METTL3_EV_vs_WT_F03.20892.20892.3 1.12E-13 22/72 R.TMNNFLDREQYGQYALAVR.G sp|Q02413|DSG1_HUMAN 1 2288.1008 150.64 35774 20892 3 2288.099017 763.7075 Desmoglein-1 OS=Homo sapiens OX=9606 GN=DSG1 PE=1 SV=2 5.73 3395.7 - 3.51E+06 - - - -0.7797 - 4.005 0.711 - 733.6 1 2 1 -0.0018 19 0 0 0 4.00E+07 2.65E+05 - - - 9.8754 0.9999 221125_WJC_METTL3_EV_vs_WT_F03.20893.20893.3 0.000476 Nov-48 K.VESLQEEIAFLKK.L "sp|P08670|VIME_HUMAN,tr|B0YJC5|B0YJC5_HUMAN,tr|B0YJC4|B0YJC4_HUMAN" 3 1532.845 2.03 35775 20893 3 1532.844838 511.9556 Vimentin OS=Homo sapiens OX=9606 GN=VIM PE=1 SV=4 4.79 3395.8 - 2.73E+06 - - - -0.1122 - 2.183 0.441 - 159.5 1 2 0 -0.0002 13 0 0 0 1.67E+08 8.22E+07 - - - 5.5734 1 221125_WJC_METTL3_EV_vs_WT_F03.20894.20894.2 4.97E-07 18/28 K.NAVITVPAYFNDSQR[166.11].Q "sp|P38646|GRP75_HUMAN,sp|P0DMV8|HS71A_HUMAN,sp|P34931|HS71L_HUMAN,sp|P0DMV9|HS71B_HUMAN,tr|H0Y8K0|H0Y8K0_HUMAN,tr|A0A7I2V2S7|A0A7I2V2S7_HUMAN,tr|A0A7I2V2G2|A0A7I2V2G2_HUMAN,tr|Q53FA3|Q53FA3_HUMAN,tr|A0A7I2V3F7|A0A7I2V3F7_HUMAN,tr|A0A7I2YQB2|A0A7I2YQB2_HUMAN,tr|A0A0G2JIW1|A0A0G2JIW1_HUMAN,tr|D6RCD7|D6RCD7_HUMAN" 12 1703.8507 0.38 35776 20894 2 1703.850814 852.9326 "Stress-70 protein, mitochondrial OS=Homo sapiens OX=9606 GN=HSPA9 PE=1 SV=2" 5.84 3395.8 - 4.59E+06 - - - 0.0939 - 2.901 0.666 - 798.5 1 2 0 0.0002 15 0 0 0 9.50E+07 2.49E+08 - - - 6.5785 0.9999 221125_WJC_METTL3_EV_vs_WT_F03.20895.20895.3 0.00131 Dec-60 K.AFAHITGGGLLENIPR[166.11].V sp|P22102|PUR2_HUMAN 1 1674.9081 1.2 35777 20895 3 1674.907033 559.31 Trifunctional purine biosynthetic protein adenosine-3 OS=Homo sapiens OX=9606 GN=GART PE=1 SV=1 6.79 3395.9 - 3.18E+06 - - - -0.6424 - 2.317 0.385 - 155 1 2 0 -0.0011 16 0 0 0 3.14E+07 2.62E+07 - - - 4.9881 0.9998 221125_WJC_METTL3_EV_vs_WT_F03.20898.20898.3 0.000552 14/44 R.VSFELFADK[136.11]VPK[136.11].T "sp|P62937|PPIA_HUMAN,tr|C9J5S7|C9J5S7_HUMAN,tr|F8WE65|F8WE65_HUMAN,tr|A0A7I2V5J5|A0A7I2V5J5_HUMAN" 4 1394.7781 0.88 35780 20898 3 1394.777564 465.9333 Peptidyl-prolyl cis-trans isomerase A OS=Homo sapiens OX=9606 GN=PPIA PE=1 SV=2 6.04 3396.1 - 2.06E+06 - - - -0.3506 - 2.467 0.434 - 219 1 2 1 -0.0005 12 0 0 0 1.30E+08 1.47E+08 - - - 5.8815 1 221125_WJC_METTL3_EV_vs_WT_F03.20900.20900.3 9.45E-09 26/76 R.TMIQSPSGVILQEAADVHAR.Y sp|P15924|DESP_HUMAN 1 2122.0841 155.49 35782 20900 3 2122.082496 708.3686 Desmoplakin OS=Homo sapiens OX=9606 GN=DSP PE=1 SV=3 5.29 3396.3 - 1.56E+06 - - - -0.7502 - 3.988 0.469 - 622.9 1 2 0 -0.0016 20 0 0 0 5.14E+07 3.31E+05 - - - 7.1243 0.9999 221125_WJC_METTL3_EV_vs_WT_F03.20901.20901.2 8.78E-05 14/22 K.NLDENGLDLLSK.M "sp|P06493|CDK1_HUMAN,tr|A0A024QZP7|A0A024QZP7_HUMAN" 2 1329.6776 1.56 35783 20901 2 1329.676666 665.8461 Cyclin-dependent kinase 1 OS=Homo sapiens OX=9606 GN=CDK1 PE=1 SV=3 4.03 3396.4 - 1.41E+06 - - - -0.7099 - 2.088 0.515 - 508.9 1 2 0 -0.0009 12 0 0 0 2.18E+07 1.40E+07 - - - 4.7816 0.9998 221125_WJC_METTL3_EV_vs_WT_F03.20904.20904.2 2.30E-06 22-Dec K.NNSGLSFEELYR.N "sp|Q13618|CUL3_HUMAN,tr|H7C1L6|H7C1L6_HUMAN,tr|A0A087X1R9|A0A087X1R9_HUMAN" 3 1427.6681 5.27 35786 20904 2 1427.671054 714.8413 Cullin-3 OS=Homo sapiens OX=9606 GN=CUL3 PE=1 SV=2 4.53 3396.8 - 766407 - - - 2.0635 - 2.668 0.549 - 637.4 1 2 0 0.0029 12 0 0 0 1.37E+07 2.61E+06 - - - 5.677 1 221125_WJC_METTL3_EV_vs_WT_F03.20909.20909.3 4.85E-06 20/68 K.QQLSAEELDAQLDAYNAR[166.11].M "sp|Q86V81|THOC4_HUMAN,tr|E9PB61|E9PB61_HUMAN" 2 2043.9737 0.7 35789 20909 3 2043.971957 682.3318 THO complex subunit 4 OS=Homo sapiens OX=9606 GN=ALYREF PE=1 SV=3 3.92 3397.5 - 7.82E+06 - - - -0.8444 - 2.834 0.499 - 524.5 1 2 0 -0.0017 18 0 0 0 5.43E+07 7.74E+07 - - - 6.6968 0.9996 221125_WJC_METTL3_EV_vs_WT_F03.20910.20910.3 0.000376 Nov-44 R.VSFELFADKVPK.T "sp|P62937|PPIA_HUMAN,tr|C9J5S7|C9J5S7_HUMAN,tr|F8WE65|F8WE65_HUMAN,tr|A0A7I2V5J5|A0A7I2V5J5_HUMAN" 4 1378.7497 0.88 35790 20910 3 1378.748707 460.5905 Peptidyl-prolyl cis-trans isomerase A OS=Homo sapiens OX=9606 GN=PPIA PE=1 SV=2 6.04 3397.5 - 5.57E+06 - - - -0.6861 - 2.111 0.417 - 136.2 1 2 1 -0.0009 12 0 0 0 1.30E+08 1.47E+08 - - - 5.2599 0.9999 221125_WJC_METTL3_EV_vs_WT_F03.20911.20911.3 3.96E-05 13/56 R.QYYTLLNQAPDMLHR.F "sp|Q13283|G3BP1_HUMAN,tr|E5RH00|E5RH00_HUMAN,tr|E5RH42|E5RH42_HUMAN,tr|A0A7I2V4Y8|A0A7I2V4Y8_HUMAN,tr|A0A7I2V3C4|A0A7I2V3C4_HUMAN,tr|A0A7P0P2U7|A0A7P0P2U7_HUMAN,tr|A0A7I2V2S5|A0A7I2V2S5_HUMAN,tr|A0A7I2YQU8|A0A7I2YQU8_HUMAN,tr|E5RJU8|E5RJU8_HUMAN,tr|A0A7I2V651|A0A7I2V651_HUMAN,tr|E5RIF8|E5RIF8_HUMAN,tr|A0A7I2YQN9|A0A7I2YQN9_HUMAN" 12 1861.9145 1.04 35791 20911 3 1861.913225 621.6454 Ras GTPase-activating protein-binding protein 1 OS=Homo sapiens OX=9606 GN=G3BP1 PE=1 SV=1 6.74 3397.5 - 6.29E+06 - - - -0.6864 - 2.417 0.431 - 169.6 1 2 0 -0.0013 15 0 0 0 3.04E+08 2.91E+08 - - - 5.6477 1 221125_WJC_METTL3_EV_vs_WT_F03.20913.20913.3 0.000257 19/60 K.KPELVISYLPPGMASK.L "sp|P78347|GTF2I_HUMAN,tr|A0A494C1K3|A0A494C1K3_HUMAN" 2 1728.9484 1.72 35793 20913 3 1728.94945 577.3234 General transcription factor II-I OS=Homo sapiens OX=9606 GN=GTF2I PE=1 SV=2 8.5 3397.7 - 2.72E+06 - - - 0.5905 - 3.334 0.557 - 445.9 1 2 0 0.001 16 0 0 0 3.88E+07 2.26E+07 - - - 7.8395 1 221125_WJC_METTL3_EV_vs_WT_F03.20914.20914.2 2.67E-07 26-Dec A.SDVLELTDDNFESR[166.11].L "sp|P30101|PDIA3_HUMAN,tr|F8WBW5|F8WBW5_HUMAN,tr|F8WBS6|F8WBS6_HUMAN,tr|H7BZJ3|H7BZJ3_HUMAN" 4 1648.7456 0.53 35794 20914 2 1648.745349 825.3801 Protein disulfide-isomerase A3 OS=Homo sapiens OX=9606 GN=PDIA3 PE=1 SV=4 3.77 3397.8 - 2.17E+06 - - - -0.1401 - 2.816 0.589 - 477.7 1 1 0 -0.0002 14 0 0 0 2.14E+07 4.01E+07 - - - 5.9894 1 221125_WJC_METTL3_EV_vs_WT_F03.20915.20915.2 4.65E-16 19/34 K.QQLSAEELDAQLDAYNAR.M "sp|Q86V81|THOC4_HUMAN,tr|E9PB61|E9PB61_HUMAN" 2 2033.9654 0.82 35795 20915 2 2033.967001 1017.99 THO complex subunit 4 OS=Homo sapiens OX=9606 GN=ALYREF PE=1 SV=3 3.92 3397.9 - 1.97E+06 - - - 0.7807 - 3.905 0.706 - 1423.7 1 2 0 0.0016 18 0 0 0 2.29E+07 2.78E+07 - - - 7.6042 0.9999 221125_WJC_METTL3_EV_vs_WT_F03.20916.20916.3 1.19E-05 17/60 R.QVNLEIGVNNEAPFAR.D sp|Q14574|DSC3_HUMAN 1 1769.906 0.99 35796 20916 3 1769.905552 590.976 Desmocollin-3 OS=Homo sapiens OX=9606 GN=DSC3 PE=1 SV=3 4.53 3398 - 1.40E+06 - - - -0.2797 - 2.421 0.426 - 184.8 1 2 0 -0.0005 16 0 0 0 1.15E+07 1.16E+07 - - - 5.558 0.9999 221125_WJC_METTL3_EV_vs_WT_F03.20919.20919.2 2.51E-07 Dec-36 K.AAGALLNGPPQFSTAPEIK[136.11].A "sp|O75175|CNOT3_HUMAN,tr|B7Z6J7|B7Z6J7_HUMAN,tr|A0A2H2FJL5|A0A2H2FJL5_HUMAN,tr|H7C3F5|H7C3F5_HUMAN,tr|A0A2R8Y4W0|A0A2R8Y4W0_HUMAN,tr|H0Y5X7|H0Y5X7_HUMAN" 6 1889.0138 3.91 35799 20919 2 1889.011291 945.5142 CCR4-NOT transcription complex subunit 3 OS=Homo sapiens OX=9606 GN=CNOT3 PE=1 SV=1 6.05 3398.4 - 411012 - - - -1.3351 - 2.854 0.53 - 348.6 1 2 0 -0.0025 19 0 0 0 2.33E+07 5.97E+06 - - - 5.5331 1 221125_WJC_METTL3_EV_vs_WT_F03.20921.20921.2 0.000735 20/36 K.AAGALLNGPPQFSTAPEIK.A "sp|O75175|CNOT3_HUMAN,tr|B7Z6J7|B7Z6J7_HUMAN,tr|A0A2H2FJL5|A0A2H2FJL5_HUMAN,tr|H7C3F5|H7C3F5_HUMAN,tr|A0A2R8Y4W0|A0A2R8Y4W0_HUMAN,tr|H0Y5X7|H0Y5X7_HUMAN" 6 1880.9996 3.91 35800 20921 2 1881.000882 941.5071 CCR4-NOT transcription complex subunit 3 OS=Homo sapiens OX=9606 GN=CNOT3 PE=1 SV=1 6.05 3398.6 - 1.29E+06 - - - 0.6746 - 3.991 0.568 - 1261 1 2 0 0.0013 19 0 0 0 2.33E+07 5.97E+06 - - - 6.6386 0.9987 221125_WJC_METTL3_EV_vs_WT_F03.20923.20923.2 1.72E-06 15/22 R.VSFELFADK[136.11]VPK[136.11].T "sp|P62937|PPIA_HUMAN,tr|C9J5S7|C9J5S7_HUMAN,tr|F8WE65|F8WE65_HUMAN,tr|A0A7I2V5J5|A0A7I2V5J5_HUMAN" 4 1394.7781 0.56 35801 20923 2 1394.779015 698.3963 Peptidyl-prolyl cis-trans isomerase A OS=Homo sapiens OX=9606 GN=PPIA PE=1 SV=2 6.04 3398.8 - 2.08E+06 - - - 0.6897 - 2.612 0.505 - 610.7 1 2 1 0.001 12 0 0 0 2.47E+07 4.41E+07 - - - 5.2969 0.9999 221125_WJC_METTL3_EV_vs_WT_F03.20924.20924.3 1.58E-05 16/48 R.IVYYLMNIHVQPR.T "sp|Q16875|F263_HUMAN,sp|O60825|F262_HUMAN,tr|A0A1W2PR17|A0A1W2PR17_HUMAN,tr|Q5W015|Q5W015_HUMAN,tr|F2Z2I2|F2Z2I2_HUMAN,tr|Q5VX20|Q5VX20_HUMAN" 6 1644.881 4.04 35802 20924 3 1644.885513 549.3009 "6-phosphofructo-2-kinase\fructose-2,6-bisphosphatase 3 OS=Homo sapiens OX=9606 GN=PFKFB3 PE=1 SV=1" 8.6 3398.9 - 1.70E+06 - - - 2.7327 - 2.85 0.502 - 412.2 1 2 0 0.0045 13 0 0 0 1.97E+07 4.88E+06 - - - 6.9751 1 221125_WJC_METTL3_EV_vs_WT_F03.20926.20926.2 1.06E-10 17/26 R.AVFQANQENLPILK.R sp|P05023|AT1A1_HUMAN 1 1583.8671 1.59 35804 20926 2 1583.865734 792.9408 Sodium\potassium-transporting ATPase subunit alpha-1 OS=Homo sapiens OX=9606 GN=ATP1A1 PE=1 SV=1 6.05 3399.1 - 1.45E+06 - - - -0.889 - 3.057 0.63 - 796.7 1 2 0 -0.0014 14 0 0 0 2.37E+07 1.49E+07 - - - 6.4979 0.9975 221125_WJC_METTL3_EV_vs_WT_F03.20927.20927.2 0.000378 15/22 R.VSFELFADKVPK.T "sp|P62937|PPIA_HUMAN,tr|C9J5S7|C9J5S7_HUMAN,tr|F8WE65|F8WE65_HUMAN,tr|A0A7I2V5J5|A0A7I2V5J5_HUMAN" 4 1378.7497 0.57 35805 20927 2 1378.752506 690.3821 Peptidyl-prolyl cis-trans isomerase A OS=Homo sapiens OX=9606 GN=PPIA PE=1 SV=2 6.04 3399.2 - 1.31E+06 - - - 2.0693 - 2.75 0.496 - 559.7 1 2 1 0.0029 12 0 0 0 2.47E+07 4.29E+07 - - - 5.3653 1 221125_WJC_METTL3_EV_vs_WT_F03.20928.20928.2 4.30E-09 16/30 K.TPVEEVPAAIAPFQGR.V sp|Q15393|SF3B3_HUMAN 1 1680.8835 1.16 35806 20928 2 1680.886202 841.449 Splicing factor 3B subunit 3 OS=Homo sapiens OX=9606 GN=SF3B3 PE=1 SV=4 4.53 3399.3 - 1.06E+06 - - - 1.595 - 3.19 0.617 - 424.8 1 2 0 0.0027 16 0 0 0 2.60E+07 2.24E+07 - - - 6.4493 1 221125_WJC_METTL3_EV_vs_WT_F03.20929.20929.3 1.56E-11 18/92 R.VYAPASTLVDQPYANEGTVVVTER.V sp|Q14126|DSG2_HUMAN 1 2578.2915 2.04 35807 20929 3 2578.287579 860.4378 Desmoglein-2 OS=Homo sapiens OX=9606 GN=DSG2 PE=1 SV=2 4.14 3399.5 - 876863 - - - -1.52 - 3.222 0.603 - 286.8 1 2 0 -0.0039 24 0 0 0 1.64E+07 8.03E+06 - - - 7.9792 0.9998 221125_WJC_METTL3_EV_vs_WT_F03.20930.20930.2 1.95E-06 24-Dec R.LGSTVFVANLDYK[136.11].V "sp|P52272|HNRPM_HUMAN,tr|M0R019|M0R019_HUMAN,tr|A0A087X0X3|A0A087X0X3_HUMAN,tr|M0QYQ7|M0QYQ7_HUMAN,tr|M0R2T0|M0R2T0_HUMAN" 5 1433.7646 2.28 35808 20930 2 1433.765924 717.8896 Heterogeneous nuclear ribonucleoprotein M OS=Homo sapiens OX=9606 GN=HNRNPM PE=1 SV=3 5.83 3399.6 - 763794 - - - 0.9367 - 2.482 0.42 - 484.4 1 2 0 0.0013 13 0 0 0 1.73E+07 7.59E+06 - - - 4.4758 0.9999 221125_WJC_METTL3_EV_vs_WT_F03.20932.20932.3 3.99E-05 Dec-44 K.AHFLEAVDDAFK.T "sp|Q96JG8|MAGD4_HUMAN,tr|A0A804HKI1|A0A804HKI1_HUMAN" 2 1361.6616 3.21 35810 20932 3 1361.660188 454.8945 Melanoma-associated antigen D4 OS=Homo sapiens OX=9606 GN=MAGED4 PE=1 SV=3 4.54 3399.9 - 259356 - - - -1.012 - 2.086 0.464 - 176.1 1 2 0 -0.0014 12 0 0 0 2.98E+06 9.28E+05 - - - 5.7508 0.9973 221125_WJC_METTL3_EV_vs_WT_F03.20934.20934.3 0.0555 Dec-48 K.SVFVNWPHLEEAR.V "sp|Q8IZH2|XRN1_HUMAN,tr|H7C5E4|H7C5E4_HUMAN" 2 1582.7892 0.74 35811 20934 3 1582.795091 528.6037 5'-3' exoribonuclease 1 OS=Homo sapiens OX=9606 GN=XRN1 PE=1 SV=1 5.38 3400.1 - 458073 - - - 3.7055 - 2.17 0.297 - 124.6 1 2 0 0.0059 13 0 0 0 1.94E+07 2.64E+07 - - - 3.9501 0.9999 221125_WJC_METTL3_EV_vs_WT_F03.20937.20937.3 3.35E-07 14/56 K.NAVITVPAYFNDSQR.Q "sp|P38646|GRP75_HUMAN,sp|P0DMV8|HS71A_HUMAN,sp|P34931|HS71L_HUMAN,sp|P0DMV9|HS71B_HUMAN,tr|H0Y8K0|H0Y8K0_HUMAN,tr|A0A7I2V2S7|A0A7I2V2S7_HUMAN,tr|A0A7I2V2G2|A0A7I2V2G2_HUMAN,tr|Q53FA3|Q53FA3_HUMAN,tr|A0A7I2V3F7|A0A7I2V3F7_HUMAN,tr|A0A7I2YQB2|A0A7I2YQB2_HUMAN,tr|A0A0G2JIW1|A0A0G2JIW1_HUMAN,tr|D6RCD7|D6RCD7_HUMAN" 12 1693.8424 0.31 35813 20937 3 1693.845963 565.6214 "Stress-70 protein, mitochondrial OS=Homo sapiens OX=9606 GN=HSPA9 PE=1 SV=2" 5.84 3400.4 - 2.77E+06 - - - 2.1129 - 2.353 0.508 - 239.5 1 2 0 0.0036 15 0 0 0 1.91E+07 6.17E+07 - - - 6.4355 1 221125_WJC_METTL3_EV_vs_WT_F03.20939.20939.3 9.59E-05 20/76 K.SFGSAQEFAWAHDSSEYAIR[166.11].E "sp|P35606|COPB2_HUMAN,tr|H0Y938|H0Y938_HUMAN,tr|A0A7I2V258|A0A7I2V258_HUMAN,tr|H0YAC7|H0YAC7_HUMAN" 4 2268.0111 0.65 35815 20939 3 2268.00626 757.011 Coatomer subunit beta' OS=Homo sapiens OX=9606 GN=COPB2 PE=1 SV=2 4.65 3400.5 - 2.26E+06 - - - -2.1477 - 2.768 0.561 - 279.7 1 2 0 -0.0049 20 0 0 0 8.49E+06 1.30E+07 - - - 7.2632 0.9879 221125_WJC_METTL3_EV_vs_WT_F03.20942.20942.3 0.000114 13/52 L.LQPLNVEIDPEIQK.V sp|P04264|K2C1_HUMAN 1 1634.8879 184.43 35818 20942 3 1634.890779 545.9699 "Keratin, type II cytoskeletal 1 OS=Homo sapiens OX=9606 GN=KRT1 PE=1 SV=6" 4.14 3400.8 - 1.66E+06 - - - 1.7383 - 2.442 0.415 - 240 1 1 0 0.0028 14 0 0 0 6.87E+07 3.72E+05 - - - 5.5387 0.9999 221125_WJC_METTL3_EV_vs_WT_F03.20943.20943.2 3.68E-08 24-Dec R.LGSTVFVANLDYK.V "sp|P52272|HNRPM_HUMAN,tr|M0R019|M0R019_HUMAN,tr|A0A087X0X3|A0A087X0X3_HUMAN,tr|M0QYQ7|M0QYQ7_HUMAN,tr|M0R2T0|M0R2T0_HUMAN" 5 1425.7504 2.34 35819 20943 2 1425.75079 713.8825 Heterogeneous nuclear ribonucleoprotein M OS=Homo sapiens OX=9606 GN=HNRNPM PE=1 SV=3 5.83 3400.9 - 1.58E+06 - - - 0.2869 - 2.709 0.533 - 593.8 1 2 0 0.0004 13 0 0 0 1.78E+07 7.59E+06 - - - 5.5354 0.999 221125_WJC_METTL3_EV_vs_WT_F03.20944.20944.2 0.0221 16-Aug K.ALQFLEEVK[136.11].V sp|P40227|TCPZ_HUMAN 1 1083.6056 0.38 35820 20944 2 1083.606424 542.8101 T-complex protein 1 subunit zeta OS=Homo sapiens OX=9606 GN=CCT6A PE=1 SV=3 4.53 3401 - 1.47E+06 - - - 0.7964 - 1.671 0.27 - 172.9 1 2 0 0.0009 9 0 0 0 4.22E+06 1.11E+07 - - - 2.5203 0.9999 221125_WJC_METTL3_EV_vs_WT_F03.20945.20945.2 2.07E-05 Sep-32 K.VLQQGHFEDDDPDGFLG.- "sp|Q6SPF0|SAMD1_HUMAN,tr|E9PIW9|E9PIW9_HUMAN" 2 1887.8275 - 35821 20945 2 1887.827729 944.921 Sterile alpha motif domain-containing protein 1 OS=Homo sapiens OX=9606 GN=SAMD1 PE=1 SV=1 3.71 3401.1 - 938610 - - - 0.1096 - 2.016 0.596 - 139.2 1 2 0 0.0002 17 0 0 0 - - - - - 5.1667 1 221125_WJC_METTL3_EV_vs_WT_F03.20946.20946.3 8.90E-08 15/40 R.TQDEC[160.03]ILHFLR.L "sp|Q8TAQ2|SMRC2_HUMAN,sp|Q92922|SMRC1_HUMAN,tr|F8VXC8|F8VXC8_HUMAN" 3 1430.6976 3.3 35822 20946 3 1430.696559 477.9065 SWI\SNF complex subunit SMARCC2 OS=Homo sapiens OX=9606 GN=SMARCC2 PE=1 SV=1 5.29 3401.3 - 633247 - - - -0.7514 - 3.039 0.569 - 503.3 1 2 0 -0.0011 11 0 0 0 4.22E+07 1.28E+07 - - - 8.0412 1 221125_WJC_METTL3_EV_vs_WT_F03.20947.20947.2 2.82E-11 15/28 R.QYYTLLNQAPDMLHR[166.11].F "sp|Q13283|G3BP1_HUMAN,tr|E5RH00|E5RH00_HUMAN,tr|E5RH42|E5RH42_HUMAN,tr|A0A7I2V4Y8|A0A7I2V4Y8_HUMAN,tr|A0A7I2V3C4|A0A7I2V3C4_HUMAN,tr|A0A7P0P2U7|A0A7P0P2U7_HUMAN,tr|A0A7I2V2S5|A0A7I2V2S5_HUMAN,tr|A0A7I2YQU8|A0A7I2YQU8_HUMAN,tr|E5RJU8|E5RJU8_HUMAN,tr|A0A7I2V651|A0A7I2V651_HUMAN,tr|E5RIF8|E5RIF8_HUMAN,tr|A0A7I2YQN9|A0A7I2YQN9_HUMAN" 12 1871.9228 1.39 35823 20947 2 1872.930476 936.9687 Ras GTPase-activating protein-binding protein 1 OS=Homo sapiens OX=9606 GN=G3BP1 PE=1 SV=1 6.74 3401.4 - 578652 - - - 538.3251 - 3.077 0.633 - 986.1 1 2 0 1.0077 15 0 0 0 6.27E+06 4.50E+06 - - - 6.1632 0.9999 221125_WJC_METTL3_EV_vs_WT_F03.20950.20950.3 1.64E-07 17/48 K.VESLQEEIAFLK[136.11]K[136.11].L "sp|P08670|VIME_HUMAN,tr|B0YJC5|B0YJC5_HUMAN,tr|B0YJC4|B0YJC4_HUMAN" 3 1548.8734 2.07 35825 20950 3 1548.875399 517.2984 Vimentin OS=Homo sapiens OX=9606 GN=VIM PE=1 SV=4 4.79 3401.8 - 6.52E+06 - - - 1.2842 - 3.005 0.403 - 449.4 1 2 0 0.002 13 0 0 0 1.63E+08 7.90E+07 - - - 6.0157 0.9944 221125_WJC_METTL3_EV_vs_WT_F03.20952.20952.2 2.30E-05 26-Dec L.LQPLNVEIDPEIQK.V sp|P04264|K2C1_HUMAN 1 1634.8879 63.42 35826 20952 2 1634.888734 818.4512 "Keratin, type II cytoskeletal 1 OS=Homo sapiens OX=9606 GN=KRT1 PE=1 SV=6" 4.14 3402 - 9.61E+06 - - - 0.4875 - 2.309 0.597 - 385 1 1 0 0.0008 14 0 0 0 2.83E+08 4.46E+06 - - - 5.5501 1 221125_WJC_METTL3_EV_vs_WT_F03.20953.20953.3 0.00012 14/56 K.NAVITVPAYFNDSQR[166.11].Q "sp|P38646|GRP75_HUMAN,sp|P0DMV8|HS71A_HUMAN,sp|P34931|HS71L_HUMAN,sp|P0DMV9|HS71B_HUMAN,tr|H0Y8K0|H0Y8K0_HUMAN,tr|A0A7I2V2S7|A0A7I2V2S7_HUMAN,tr|A0A7I2V2G2|A0A7I2V2G2_HUMAN,tr|Q53FA3|Q53FA3_HUMAN,tr|A0A7I2V3F7|A0A7I2V3F7_HUMAN,tr|A0A7I2YQB2|A0A7I2YQB2_HUMAN,tr|A0A0G2JIW1|A0A0G2JIW1_HUMAN,tr|D6RCD7|D6RCD7_HUMAN" 12 1703.8507 0.35 35827 20953 3 1703.851289 568.9575 "Stress-70 protein, mitochondrial OS=Homo sapiens OX=9606 GN=HSPA9 PE=1 SV=2" 5.84 3402 - 7.10E+06 - - - 0.3727 - 2.46 0.451 - 330.5 1 2 0 0.0006 15 0 0 0 2.24E+07 6.38E+07 - - - 5.9169 0.9999 221125_WJC_METTL3_EV_vs_WT_F03.20954.20954.2 2.80E-08 24-Nov K.DTNGSQFFITTVK.T "sp|P23284|PPIB_HUMAN,tr|A0A7P0Z497|A0A7P0Z497_HUMAN,tr|A0A7P0TB45|A0A7P0TB45_HUMAN" 3 1456.7198 0.43 35828 20954 2 1456.720194 729.3672 Peptidyl-prolyl cis-trans isomerase B OS=Homo sapiens OX=9606 GN=PPIB PE=1 SV=2 5.84 3402.1 - 3.18E+06 - - - 0.2643 - 2.561 0.536 - 478.9 1 2 0 0.0004 13 0 0 0 5.41E+07 1.26E+08 - - - 5.4133 0.9998 221125_WJC_METTL3_EV_vs_WT_F03.20955.20955.2 6.99E-05 22-Dec K.ELEEIVQPIISK[136.11].L "sp|P11021|BIP_HUMAN,tr|A0A7P0TB36|A0A7P0TB36_HUMAN,tr|A0A7P0TAI0|A0A7P0TAI0_HUMAN" 3 1404.7955 0.81 35829 20955 2 1404.796393 703.405 Endoplasmic reticulum chaperone BiP OS=Homo sapiens OX=9606 GN=HSPA5 PE=1 SV=2 4.25 3402.1 - 2.04E+06 - - - 0.6022 - 2.437 0.435 - 496.4 1 2 0 0.0008 12 0 0 0 2.80E+07 3.47E+07 - - - 4.5974 1 221125_WJC_METTL3_EV_vs_WT_F03.20958.20958.2 2.40E-09 14/26 R.AVFQANQENLPILK[136.11].R sp|P05023|AT1A1_HUMAN 1 1591.8813 1.59 35832 20958 2 1591.883246 796.9479 Sodium\potassium-transporting ATPase subunit alpha-1 OS=Homo sapiens OX=9606 GN=ATP1A1 PE=1 SV=1 6.05 3402.4 - 1.40E+06 - - - 1.1961 - 2.572 0.595 - 504.4 1 2 0 0.0019 14 0 0 0 2.37E+07 1.49E+07 - - - 5.8057 0.9999 221125_WJC_METTL3_EV_vs_WT_F03.20959.20959.3 2.07E-05 13/60 K.VDQIQEIVTGNPTVIK[136.11].M "sp|P46940|IQGA1_HUMAN,tr|H0YLE8|H0YLE8_HUMAN,tr|A0A0J9YXZ5|A0A0J9YXZ5_HUMAN" 3 1760.9764 1.03 35833 20959 3 1760.977606 587.9994 Ras GTPase-activating-like protein IQGAP1 OS=Homo sapiens OX=9606 GN=IQGAP1 PE=1 SV=1 4.37 3402.5 - 1.21E+06 - - - 0.7047 - 2.34 0.418 - 198 1 2 0 0.0012 16 0 0 0 6.80E+06 6.58E+06 - - - 5.3813 0.999 221125_WJC_METTL3_EV_vs_WT_F03.20960.20960.2 2.33E-05 16/28 K.NVIVNGLVLASDGQK[136.11].M "sp|P41252|SYIC_HUMAN,tr|A0A804HL54|A0A804HL54_HUMAN,tr|A0A804HKU1|A0A804HKU1_HUMAN,tr|A0A804HK69|A0A804HK69_HUMAN,tr|A0A804HIV9|A0A804HIV9_HUMAN,tr|A0A804HJN6|A0A804HJN6_HUMAN,tr|A0A804HHW9|A0A804HHW9_HUMAN,tr|A0A0A0MSX9|A0A0A0MSX9_HUMAN,tr|J3KR24|J3KR24_HUMAN,tr|A0A804HJ36|A0A804HJ36_HUMAN" 10 1533.8606 0.41 35834 20960 2 1533.854663 767.9376 "Isoleucine--tRNA ligase, cytoplasmic OS=Homo sapiens OX=9606 GN=IARS1 PE=1 SV=2" 5.84 3402.6 - 1.20E+06 - - - -3.8752 - 2.901 0.447 - 697.2 1 2 0 -0.0059 15 0 0 0 3.14E+06 7.69E+06 - - - 4.9592 1 221125_WJC_METTL3_EV_vs_WT_F03.20961.20961.3 2.13E-06 20/76 K.SFGSAQEFAWAHDSSEYAIR.E "sp|P35606|COPB2_HUMAN,tr|H0Y938|H0Y938_HUMAN,tr|A0A7I2V258|A0A7I2V258_HUMAN,tr|H0YAC7|H0YAC7_HUMAN" 4 2258.0029 0.17 35835 20961 3 2258.000684 753.6749 Coatomer subunit beta' OS=Homo sapiens OX=9606 GN=COPB2 PE=1 SV=2 4.65 3402.8 - 1.14E+06 - - - -0.9641 - 3.192 0.609 - 316.3 1 2 0 -0.0022 20 0 0 0 8.99E+06 5.23E+07 - - - 8.1449 1 221125_WJC_METTL3_EV_vs_WT_F03.20962.20962.3 1.41E-09 16/60 R.YSGLC[160.03]PHVVVLVATVR.A "sp|P11586|C1TC_HUMAN,tr|F5H2F4|F5H2F4_HUMAN,tr|V9GZ78|V9GZ78_HUMAN,tr|V9GYY3|V9GYY3_HUMAN,tr|A0A494C1T2|A0A494C1T2_HUMAN" 5 1768.9658 1.44 35836 20962 3 1768.970237 590.6625 "C-1-tetrahydrofolate synthase, cytoplasmic OS=Homo sapiens OX=9606 GN=MTHFD1 PE=1 SV=4" 8.23 3402.8 - 867666 - - - 2.502 - 2.7 0.615 - 186.4 1 2 0 0.0044 16 0 0 0 6.54E+06 4.55E+06 - - - 7.944 1 221125_WJC_METTL3_EV_vs_WT_F03.20963.20963.3 0.000304 16/40 R.TQDEC[160.03]ILHFLR[166.11].L "sp|Q8TAQ2|SMRC2_HUMAN,sp|Q92922|SMRC1_HUMAN,tr|F8VXC8|F8VXC8_HUMAN" 3 1440.7059 3.3 35837 20963 3 1440.703759 481.2426 SWI\SNF complex subunit SMARCC2 OS=Homo sapiens OX=9606 GN=SMARCC2 PE=1 SV=1 5.29 3403 - 743241 - - - -1.4889 - 2.754 0.455 - 547.9 1 2 0 -0.0021 11 0 0 0 4.22E+07 1.28E+07 - - - 6.4901 1 221125_WJC_METTL3_EV_vs_WT_F03.20965.20965.3 2.36E-06 Dec-48 R.GHTAEILDFALSK[136.11].D "sp|Q13685|AAMP_HUMAN,tr|H7C0R2|H7C0R2_HUMAN,tr|C9JG97|C9JG97_HUMAN,tr|C9JEH3|C9JEH3_HUMAN" 4 1408.7442 1.24 35839 20965 3 1408.743393 470.5887 Angio-associated migratory cell protein OS=Homo sapiens OX=9606 GN=AAMP PE=1 SV=2 5.32 3403.2 - 722883 - - - -0.5587 - 2.449 0.492 - 291.4 1 2 0 -0.0008 13 0 0 0 1.57E+07 1.27E+07 - - - 6.4535 0.9992 221125_WJC_METTL3_EV_vs_WT_F03.20966.20966.3 0.00393 Dec-52 R.AVFQANQENLPILK.R sp|P05023|AT1A1_HUMAN 1 1583.8671 1.43 35840 20966 3 1583.867145 528.963 Sodium\potassium-transporting ATPase subunit alpha-1 OS=Homo sapiens OX=9606 GN=ATP1A1 PE=1 SV=1 6.05 3403.3 - 721729 - - - 0.0019 - 1.832 0.297 - 118.3 1 2 0 0 14 0 0 0 5.74E+06 4.02E+06 - - - 3.4601 0.9998 221125_WJC_METTL3_EV_vs_WT_F03.20968.20968.2 1.06E-05 14/30 K.VDQIQEIVTGNPTVIK[136.11].M "sp|P46940|IQGA1_HUMAN,tr|H0YLE8|H0YLE8_HUMAN,tr|A0A0J9YXZ5|A0A0J9YXZ5_HUMAN" 3 1760.9764 1.22 35842 20968 2 1760.977445 881.4955 Ras GTPase-activating-like protein IQGAP1 OS=Homo sapiens OX=9606 GN=IQGAP1 PE=1 SV=1 4.37 3403.6 - 611601 - - - 0.6133 - 2.084 0.518 - 286.4 1 2 0 0.0011 16 0 0 0 3.41E+06 2.79E+06 - - - 4.6719 0.9998 221125_WJC_METTL3_EV_vs_WT_F03.20973.20973.2 0.00294 16-Oct R.YLDVSILGK[136.11].F sp|Q86U44|MTA70_HUMAN 1 1014.5841 0.02 35846 20973 2 1014.5855 508.2993 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 5.83 3404.2 - 2.03E+07 - - - 1.3818 - 1.925 0.479 - 242.2 1 2 0 0.0014 9 0 0 0 1.27E+07 5.98E+08 - - - 4.4732 0.9637 221125_WJC_METTL3_EV_vs_WT_F03.20974.20974.3 0.0912 Nov-60 K.NFLTTAIRPHGIFGPR.D "sp|Q15738|NSDHL_HUMAN,tr|C9JDR0|C9JDR0_HUMAN" 2 1795.9846 0.03 35847 20974 3 1795.991011 599.6688 "Sterol-4-alpha-carboxylate 3-dehydrogenase, decarboxylating OS=Homo sapiens OX=9606 GN=NSDHL PE=1 SV=2" 12 3404.3 - 327161 - - - 3.5852 - 1.685 0.198 - 125.8 1 2 0 0.0064 16 0 0 0 1.31E+06 4.81E+07 - - - 2.0845 1 221125_WJC_METTL3_EV_vs_WT_F03.20976.20976.3 2.76E-10 23/64 K.LGVQVVITDPEK[136.11]LDQIR[166.11].Q "sp|P17987|TCPA_HUMAN,tr|F5GZ03|F5GZ03_HUMAN,tr|F5H282|F5H282_HUMAN,tr|E7EQR6|E7EQR6_HUMAN,tr|E7ERF2|E7ERF2_HUMAN" 5 1940.1061 0.47 35849 20976 3 1940.106762 647.7093 T-complex protein 1 subunit alpha OS=Homo sapiens OX=9606 GN=TCP1 PE=1 SV=1 4.56 3404.4 - 6.97E+06 - - - 0.317 - 4.166 0.56 - 845.2 1 2 1 0.0006 17 0 0 0 1.83E+08 3.85E+08 - - - 8.3882 0.9999 221125_WJC_METTL3_EV_vs_WT_F03.20977.20977.3 2.99E-06 23/64 K.LGVQVVITDPEKLDQIR.Q "sp|P17987|TCPA_HUMAN,tr|F5GZ03|F5GZ03_HUMAN,tr|F5H282|F5H282_HUMAN,tr|E7EQR6|E7EQR6_HUMAN,tr|E7ERF2|E7ERF2_HUMAN" 5 1922.0837 0.47 35850 20977 3 1922.08463 641.7018 T-complex protein 1 subunit alpha OS=Homo sapiens OX=9606 GN=TCP1 PE=1 SV=1 4.56 3404.4 - 3.31E+06 - - - 0.4958 - 4.09 0.467 - 821.5 1 2 1 0.001 17 0 0 0 1.83E+08 3.85E+08 - - - 7.3047 0.9998 221125_WJC_METTL3_EV_vs_WT_F03.20981.20981.2 2.14E-10 16/28 R.VWQC[160.03]GGSLEIIPC[160.03]SR.V sp|Q10471|GALT2_HUMAN 1 1760.8338 1.99 35854 20981 2 1760.836781 881.4242 Polypeptide N-acetylgalactosaminyltransferase 2 OS=Homo sapiens OX=9606 GN=GALNT2 PE=1 SV=1 5.96 3404.9 - 1.03E+06 - - - 1.6867 - 3.18 0.509 - 559.3 1 2 0 0.003 15 0 0 0 2.40E+07 1.20E+07 - - - 5.6438 1 221125_WJC_METTL3_EV_vs_WT_F03.20983.20983.2 1.19E-07 17/28 K.NVIVNGLVLASDGQK.M "sp|P41252|SYIC_HUMAN,tr|A0A804HL54|A0A804HL54_HUMAN,tr|A0A804HKU1|A0A804HKU1_HUMAN,tr|A0A804HK69|A0A804HK69_HUMAN,tr|A0A804HIV9|A0A804HIV9_HUMAN,tr|A0A804HJN6|A0A804HJN6_HUMAN,tr|A0A804HHW9|A0A804HHW9_HUMAN,tr|A0A0A0MSX9|A0A0A0MSX9_HUMAN,tr|J3KR24|J3KR24_HUMAN,tr|A0A804HJ36|A0A804HJ36_HUMAN" 10 1525.8464 0.53 35856 20983 2 1525.848217 763.9305 "Isoleucine--tRNA ligase, cytoplasmic OS=Homo sapiens OX=9606 GN=IARS1 PE=1 SV=2" 5.84 3405.1 - 965693 - - - 1.1862 - 3.142 0.626 - 840.1 1 2 0 0.0018 15 0 0 0 7.44E+06 1.41E+07 - - - 6.4788 0.9999 221125_WJC_METTL3_EV_vs_WT_F03.20985.20985.3 5.41E-07 Nov-48 K.DTNGSQFFITTVK[136.11].T "sp|P23284|PPIB_HUMAN,tr|A0A7P0Z497|A0A7P0Z497_HUMAN,tr|A0A7P0TB45|A0A7P0TB45_HUMAN" 3 1464.734 0.62 35858 20985 3 1464.734948 489.2519 Peptidyl-prolyl cis-trans isomerase B OS=Homo sapiens OX=9606 GN=PPIB PE=1 SV=2 5.84 3405.4 - 837847 - - - 0.6411 - 2.083 0.465 - 100.2 1 2 0 0.0009 13 0 0 0 3.64E+06 5.86E+06 - - - 5.7136 1 221125_WJC_METTL3_EV_vs_WT_F03.20987.20987.2 2.23E-09 28-Dec R.QYYTLLNQAPDMLHR.F "sp|Q13283|G3BP1_HUMAN,tr|E5RH00|E5RH00_HUMAN,tr|E5RH42|E5RH42_HUMAN,tr|A0A7I2V4Y8|A0A7I2V4Y8_HUMAN,tr|A0A7I2V3C4|A0A7I2V3C4_HUMAN,tr|A0A7P0P2U7|A0A7P0P2U7_HUMAN,tr|A0A7I2V2S5|A0A7I2V2S5_HUMAN,tr|A0A7I2YQU8|A0A7I2YQU8_HUMAN,tr|E5RJU8|E5RJU8_HUMAN,tr|A0A7I2V651|A0A7I2V651_HUMAN,tr|E5RIF8|E5RIF8_HUMAN,tr|A0A7I2YQN9|A0A7I2YQN9_HUMAN" 12 1861.9145 1.39 35860 20987 2 1861.918845 931.9645 Ras GTPase-activating protein-binding protein 1 OS=Homo sapiens OX=9606 GN=G3BP1 PE=1 SV=1 6.74 3405.6 - 608006 - - - 2.332 - 2.753 0.642 - 457.8 1 2 0 0.0043 15 0 0 0 6.27E+06 4.50E+06 - - - 6.2712 0.9999 221125_WJC_METTL3_EV_vs_WT_F03.20990.20990.3 2.59E-05 13/56 R.QYYTLLNQAPDMLHR[166.11].F "sp|Q13283|G3BP1_HUMAN,tr|E5RH00|E5RH00_HUMAN,tr|E5RH42|E5RH42_HUMAN,tr|A0A7I2V4Y8|A0A7I2V4Y8_HUMAN,tr|A0A7I2V3C4|A0A7I2V3C4_HUMAN,tr|A0A7P0P2U7|A0A7P0P2U7_HUMAN,tr|A0A7I2V2S5|A0A7I2V2S5_HUMAN,tr|A0A7I2YQU8|A0A7I2YQU8_HUMAN,tr|E5RJU8|E5RJU8_HUMAN,tr|A0A7I2V651|A0A7I2V651_HUMAN,tr|E5RIF8|E5RIF8_HUMAN,tr|A0A7I2YQN9|A0A7I2YQN9_HUMAN" 12 1871.9228 1.04 35862 20990 3 1871.923241 624.9815 Ras GTPase-activating protein-binding protein 1 OS=Homo sapiens OX=9606 GN=G3BP1 PE=1 SV=1 6.74 3406 - 1.90E+07 - - - 0.25 - 2.176 0.43 - 192.4 1 2 0 0.0005 15 0 0 0 3.04E+08 2.91E+08 - - - 5.3627 0.9947 221125_WJC_METTL3_EV_vs_WT_F03.20992.20992.3 0.406 Dec-48 K.QLDDLK[136.11]VELSQLR[166.11].V "sp|P42766|RL35_HUMAN,tr|F2Z388|F2Z388_HUMAN" 2 1573.8794 0.58 35864 20992 3 1573.879933 525.6338 60S ribosomal protein L35 OS=Homo sapiens OX=9606 GN=RPL35 PE=1 SV=2 4.56 3406.1 - 4.71E+06 - - - 0.312 - 1.977 0.253 - 210.3 1 2 1 0.0005 13 0 0 0 8.49E+07 1.47E+08 - - - 3.2085 0.9999 221125_WJC_METTL3_EV_vs_WT_F03.20993.20993.2 0.000122 16/26 K.VQIAVANAQELLQR.M sp|Q9Y5L4|TIM13_HUMAN 1 1551.8733 1.93 35865 20993 2 1551.873311 776.9439 Mitochondrial import inner membrane translocase subunit Tim13 OS=Homo sapiens OX=9606 GN=TIMM13 PE=1 SV=1 5.97 3406.1 - 3.39E+06 - - - 0.0135 - 3.106 0.507 - 924.5 1 2 0 0 14 0 0 0 3.69E+07 1.91E+07 - - - 5.6297 0.9999 221125_WJC_METTL3_EV_vs_WT_F03.20994.20994.3 9.33E-08 16/56 R.C[160.03]IKDEETGLC[160.03]LLPLK.E sp|P15924|DESP_HUMAN 1 1787.9161 9.03 35866 20994 3 1787.91406 596.9793 Desmoplakin OS=Homo sapiens OX=9606 GN=DSP PE=1 SV=3 4.68 3406.1 - 3.00E+06 - - - -1.165 - 2.708 0.584 - 288.2 1 2 1 -0.0021 15 0 0 0 3.43E+07 3.80E+06 - - - 7.6499 0.9993 221125_WJC_METTL3_EV_vs_WT_F03.20995.20995.2 2.78E-05 22-Oct R.EGTAFNISSWDK.N sp|Q5JSZ5|PRC2B_HUMAN 1 1353.6201 1.05 35867 20995 2 1353.615455 677.8173 Protein PRRC2B OS=Homo sapiens OX=9606 GN=PRRC2B PE=1 SV=2 4.37 3406.2 - 2.69E+06 - - - -3.4278 - 2.161 0.545 - 446.6 1 2 0 -0.0046 12 0 0 0 2.51E+07 2.40E+07 - - - 5.0924 0.9996 221125_WJC_METTL3_EV_vs_WT_F03.20997.20997.3 0.000693 Dec-48 K.QLDDLKVELSQLR.V "sp|P42766|RL35_HUMAN,tr|F2Z388|F2Z388_HUMAN" 2 1555.857 0.58 35869 20997 3 1555.856819 519.6263 60S ribosomal protein L35 OS=Homo sapiens OX=9606 GN=RPL35 PE=1 SV=2 4.56 3406.3 - 2.40E+06 - - - -0.0983 - 1.902 0.445 - 180.9 1 2 1 -0.0002 13 0 0 0 8.54E+07 1.47E+08 - - - 5.2444 0.9999 221125_WJC_METTL3_EV_vs_WT_F03.20998.20998.2 0.000157 13/26 K.VQIAVANAQELLQR[166.11].M sp|Q9Y5L4|TIM13_HUMAN 1 1561.8816 1.93 35870 20998 2 1561.880765 781.9481 Mitochondrial import inner membrane translocase subunit Tim13 OS=Homo sapiens OX=9606 GN=TIMM13 PE=1 SV=1 5.97 3406.4 - 1.85E+06 - - - -0.509 - 2.788 0.452 - 508.4 1 2 0 -0.0008 14 0 0 0 3.69E+07 1.91E+07 - - - 4.9522 0.9751 221125_WJC_METTL3_EV_vs_WT_F03.21000.21000.3 0.0494 Sep-60 R.EDFLIK[136.11]PSDNLIVC[160.03]GR[166.11].A "sp|Q13610|PWP1_HUMAN,tr|B4DJV5|B4DJV5_HUMAN,tr|F8VZ56|F8VZ56_HUMAN" 3 1892.9785 0.38 35872 21000 3 1892.968764 632.0001 Periodic tryptophan protein 1 homolog OS=Homo sapiens OX=9606 GN=PWP1 PE=1 SV=1 4.56 3406.6 - 944211 - - - -5.1453 - 1.75 0.277 - 113.5 1 2 0 -0.0097 16 0 0 0 2.55E+06 6.67E+06 - - - 3.0615 0.9725 221125_WJC_METTL3_EV_vs_WT_F03.21001.21001.2 8.84E-13 14/28 K.FDSEPSAVALELPTR[166.11].A sp|P18583|SON_HUMAN 1 1640.8285 1.61 35873 21001 2 1641.82578 821.4215 Protein SON OS=Homo sapiens OX=9606 GN=SON PE=1 SV=4 4.14 3406.7 - 920300 - - - 607.7771 - 2.912 0.552 - 663.6 1 2 0 0.9973 15 0 0 0 2.45E+07 1.52E+07 - - - 5.4327 0.9998 221125_WJC_METTL3_EV_vs_WT_F03.21003.21003.2 0.00733 16-Oct R.YLDVSILGK.F sp|Q86U44|MTA70_HUMAN 1 1006.5699 0.02 35875 21003 2 1006.569809 504.2922 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 5.83 3406.9 - 821737 - - - -0.0884 - 1.88 0.464 - 236.8 1 2 0 -0.0001 9 0 0 0 1.26E+07 5.96E+08 - - - 4.2944 0.9999 221125_WJC_METTL3_EV_vs_WT_F03.21004.21004.2 7.48E-07 14/30 K.ELPAAEPVLSPLEGTK.M "sp|Q9BY77|PDIP3_HUMAN,tr|F6VRR5|F6VRR5_HUMAN" 2 1649.8876 5.19 35876 21004 2 1649.889573 825.9511 Polymerase delta-interacting protein 3 OS=Homo sapiens OX=9606 GN=POLDIP3 PE=1 SV=2 4.25 3407 - 782041 - - - 1.194 - 2.657 0.561 - 390.3 1 2 0 0.002 16 0 0 0 7.87E+06 1.52E+06 - - - 5.5864 1 221125_WJC_METTL3_EV_vs_WT_F03.21006.21006.3 4.23E-06 11/104 R.TLYDAELSQMQSHISDTSVVLSMDNNR.S sp|P12035|K2C3_HUMAN 1 3053.407 999 35878 21006 3 3053.408602 1018.8096 "Keratin, type II cytoskeletal 3 OS=Homo sapiens OX=9606 GN=KRT3 PE=1 SV=3" 4.22 3407.3 - 540088 - - - 0.5197 - 2.625 0.495 - 110.5 1 2 0 0.0016 27 0 0 0 2.52E+07 0.00E+00 - - - 6.2786 0.9999 221125_WJC_METTL3_EV_vs_WT_F03.21007.21007.3 0.0105 14/44 R.NTISLLVAGLK[136.11]K[136.11].E "sp|Q14204|DYHC1_HUMAN,tr|A0A7P0T8N2|A0A7P0T8N2_HUMAN,tr|A0A7P0T9C4|A0A7P0T9C4_HUMAN,tr|A0A7P0TBJ7|A0A7P0TBJ7_HUMAN,tr|A0A804HHY6|A0A804HHY6_HUMAN,tr|A0A7P0T9K2|A0A7P0T9K2_HUMAN,tr|A0A7P0TB64|A0A7P0TB64_HUMAN,tr|A0A2R8Y706|A0A2R8Y706_HUMAN,tr|A0A7P0T916|A0A7P0T916_HUMAN,tr|A0A7P0TB75|A0A7P0TB75_HUMAN,tr|A0A7P0T8W5|A0A7P0T8W5_HUMAN,tr|A0A7P0T9S3|A0A7P0T9S3_HUMAN,tr|A0A7P0TAF3|A0A7P0TAF3_HUMAN,tr|A0A7P0T9F1|A0A7P0T9F1_HUMAN,tr|A0A7P0TAW9|A0A7P0TAW9_HUMAN,tr|A0A2R8YGC7|A0A2R8YGC7_HUMAN,tr|A0A7P0TA13|A0A7P0TA13_HUMAN,tr|A0A7P0T934|A0A7P0T934_HUMAN,tr|A0A7P0TAV5|A0A7P0TAV5_HUMAN,tr|A0A7P0T9Y3|A0A7P0T9Y3_HUMAN,tr|A0A7P0T7V5|A0A7P0T7V5_HUMAN,tr|A0A7P0T9R4|A0A7P0T9R4_HUMAN,tr|A0A2R8Y5T0|A0A2R8Y5T0_HUMAN,tr|A0A7P0T990|A0A7P0T990_HUMAN,tr|A0A7P0T942|A0A7P0T942_HUMAN,tr|A0A2R8YFZ7|A0A2R8YFZ7_HUMAN,tr|A0A7P0T825|A0A7P0T825_HUMAN,tr|A0A2R8Y6H2|A0A2R8Y6H2_HUMAN,tr|A0A7P0TBC9|A0A7P0TBC9_HUMAN,tr|A0A7P0TAM4|A0A7P0TAM4_HUMAN" 30 1271.8148 0.66 35879 21007 3 1271.814668 424.9455 Cytoplasmic dynein 1 heavy chain 1 OS=Homo sapiens OX=9606 GN=DYNC1H1 PE=1 SV=5 10 3407.4 - 508735 - - - -0.0826 - 2.042 0.412 - 259.1 1 2 0 -0.0001 12 0 0 0 3.74E+06 5.64E+06 - - - 5.1123 0.9989 221125_WJC_METTL3_EV_vs_WT_F03.21008.21008.3 0.129 Sep-48 K.DTNGSQFFITTVK.T "sp|P23284|PPIB_HUMAN,tr|A0A7P0Z497|A0A7P0Z497_HUMAN,tr|A0A7P0TB45|A0A7P0TB45_HUMAN" 3 1456.7198 0.57 35880 21008 3 1456.721072 486.5805 Peptidyl-prolyl cis-trans isomerase B OS=Homo sapiens OX=9606 GN=PPIB PE=1 SV=2 5.84 3407.5 - 484032 - - - 0.867 - 1.6 0.308 - 62.1 1 2 0 0.0013 13 0 0 0 3.24E+06 5.72E+06 - - - 3.2479 0.9996 221125_WJC_METTL3_EV_vs_WT_F03.21009.21009.3 0.0429 14/44 R.NTISLLVAGLKK.E "sp|Q14204|DYHC1_HUMAN,tr|A0A7P0T8N2|A0A7P0T8N2_HUMAN,tr|A0A7P0T9C4|A0A7P0T9C4_HUMAN,tr|A0A7P0TBJ7|A0A7P0TBJ7_HUMAN,tr|A0A804HHY6|A0A804HHY6_HUMAN,tr|A0A7P0T9K2|A0A7P0T9K2_HUMAN,tr|A0A7P0TB64|A0A7P0TB64_HUMAN,tr|A0A2R8Y706|A0A2R8Y706_HUMAN,tr|A0A7P0T916|A0A7P0T916_HUMAN,tr|A0A7P0TB75|A0A7P0TB75_HUMAN,tr|A0A7P0T8W5|A0A7P0T8W5_HUMAN,tr|A0A7P0T9S3|A0A7P0T9S3_HUMAN,tr|A0A7P0TAF3|A0A7P0TAF3_HUMAN,tr|A0A7P0T9F1|A0A7P0T9F1_HUMAN,tr|A0A7P0TAW9|A0A7P0TAW9_HUMAN,tr|A0A2R8YGC7|A0A2R8YGC7_HUMAN,tr|A0A7P0TA13|A0A7P0TA13_HUMAN,tr|A0A7P0T934|A0A7P0T934_HUMAN,tr|A0A7P0TAV5|A0A7P0TAV5_HUMAN,tr|A0A7P0T9Y3|A0A7P0T9Y3_HUMAN,tr|A0A7P0T7V5|A0A7P0T7V5_HUMAN,tr|A0A7P0T9R4|A0A7P0T9R4_HUMAN,tr|A0A2R8Y5T0|A0A2R8Y5T0_HUMAN,tr|A0A7P0T990|A0A7P0T990_HUMAN,tr|A0A7P0T942|A0A7P0T942_HUMAN,tr|A0A2R8YFZ7|A0A2R8YFZ7_HUMAN,tr|A0A7P0T825|A0A7P0T825_HUMAN,tr|A0A2R8Y6H2|A0A2R8Y6H2_HUMAN,tr|A0A7P0TBC9|A0A7P0TBC9_HUMAN,tr|A0A7P0TAM4|A0A7P0TAM4_HUMAN" 30 1255.7864 0.66 35881 21009 3 1255.784705 419.6027 Cytoplasmic dynein 1 heavy chain 1 OS=Homo sapiens OX=9606 GN=DYNC1H1 PE=1 SV=5 10 3407.7 - 471869 - - - -1.3283 - 1.917 0.343 - 284.8 1 2 0 -0.0017 12 0 0 0 3.74E+06 5.64E+06 - - - 4.1675 0.9998 221125_WJC_METTL3_EV_vs_WT_F03.21011.21011.3 0.00342 Sep-36 K.KTTPLLSFLK.N sp|Q9BZI7|REN3B_HUMAN 1 1146.7012 1.59 35882 21011 3 1146.699895 383.241 Regulator of nonsense transcripts 3B OS=Homo sapiens OX=9606 GN=UPF3B PE=1 SV=1 10 3407.9 - 312046 - - - -1.1782 - 1.761 0.402 - 100.4 1 2 0 -0.0014 10 0 0 0 4.51E+06 2.84E+06 - - - 4.6741 1 221125_WJC_METTL3_EV_vs_WT_F03.21013.21013.3 2.50E-09 15/56 R.GFAFVTFDDHDSVDK.L "sp|Q32P51|RA1L2_HUMAN,sp|P09651|ROA1_HUMAN,tr|A0A7I2YQX9|A0A7I2YQX9_HUMAN,tr|F8VZ49|F8VZ49_HUMAN,tr|A0A7I2V3R8|A0A7I2V3R8_HUMAN,tr|F8VTQ5|F8VTQ5_HUMAN,tr|F8W6I7|F8W6I7_HUMAN,tr|H0YH80|H0YH80_HUMAN,tr|A0A7I2V2L6|A0A7I2V2L6_HUMAN,tr|A0A7I2V3W0|A0A7I2V3W0_HUMAN,tr|A0A7I2V5U9|A0A7I2V5U9_HUMAN,tr|A0A2R8Y4L2|A0A2R8Y4L2_HUMAN" 12 1698.7526 1.3 35883 21013 3 1698.752296 567.2581 Heterogeneous nuclear ribonucleoprotein A1-like 2 OS=Homo sapiens OX=9606 GN=HNRNPA1L2 PE=2 SV=2 4.13 3408.1 - 1.12E+07 - - - -0.1589 - 3.182 0.595 - 197.5 1 2 0 -0.0003 15 0 0 0 5.70E+08 4.39E+08 - - - 8.194 1 221125_WJC_METTL3_EV_vs_WT_F03.21014.21014.3 3.50E-10 13/56 R.GFAFVTFDDHDSVDK[136.11].L "sp|Q32P51|RA1L2_HUMAN,sp|P09651|ROA1_HUMAN,tr|A0A7I2YQX9|A0A7I2YQX9_HUMAN,tr|F8VZ49|F8VZ49_HUMAN,tr|A0A7I2V3R8|A0A7I2V3R8_HUMAN,tr|F8VTQ5|F8VTQ5_HUMAN,tr|F8W6I7|F8W6I7_HUMAN,tr|H0YH80|H0YH80_HUMAN,tr|A0A7I2V2L6|A0A7I2V2L6_HUMAN,tr|A0A7I2V3W0|A0A7I2V3W0_HUMAN,tr|A0A7I2V5U9|A0A7I2V5U9_HUMAN,tr|A0A2R8Y4L2|A0A2R8Y4L2_HUMAN" 12 1706.7668 1.3 35884 21014 3 1706.76675 569.9295 Heterogeneous nuclear ribonucleoprotein A1-like 2 OS=Homo sapiens OX=9606 GN=HNRNPA1L2 PE=2 SV=2 4.13 3408.1 - 1.04E+07 - - - -0.0094 - 2.983 0.617 - 117.1 1 2 0 0 15 0 0 0 5.70E+08 4.39E+08 - - - 8.2708 0.9998 221125_WJC_METTL3_EV_vs_WT_F03.21017.21017.2 2.95E-05 20-Nov K.EIGNIISDAMK[136.11].K "sp|P10809|CH60_HUMAN,tr|A0A7I2V599|A0A7I2V599_HUMAN,tr|E7EXB4|E7EXB4_HUMAN,tr|A0A7I2YQ71|A0A7I2YQ71_HUMAN,tr|E7ESH4|E7ESH4_HUMAN,tr|A0A7I2V5M1|A0A7I2V5M1_HUMAN,tr|A0A7I2V5K3|A0A7I2V5K3_HUMAN,tr|A0A7I2V369|A0A7I2V369_HUMAN" 8 1197.6155 1.17 35887 21017 2 1197.61597 599.815 "60 kDa heat shock protein, mitochondrial OS=Homo sapiens OX=9606 GN=HSPD1 PE=1 SV=2" 4.37 3408.3 - 2.08E+06 - - - 0.4142 - 2.118 0.439 - 364.2 1 2 0 0.0005 11 0 0 0 3.77E+07 3.21E+07 - - - 4.3135 1 221125_WJC_METTL3_EV_vs_WT_F03.21022.21022.2 5.60E-05 14/28 K.AFVSGLLIGQC[160.03]SSQK[136.11].D sp|Q5SWX8|ODR4_HUMAN 1 1601.8327 1.25 35892 21022 2 1601.834801 801.9236 Protein odr-4 homolog OS=Homo sapiens OX=9606 GN=ODR4 PE=1 SV=1 8.27 3408.9 - 987964 - - - 1.3254 - 3.196 0.52 - 481 1 2 0 0.0021 15 0 0 0 1.19E+07 9.51E+06 - - - 5.7376 0.9999 221125_WJC_METTL3_EV_vs_WT_F03.21023.21023.3 0.00012 Oct-40 R.DHGLEVLGLVR[166.11].V "sp|Q9BRJ7|TIRR_HUMAN,sp|Q96DE0|NUD16_HUMAN,tr|K7EIN2|K7EIN2_HUMAN" 3 1216.6803 0.75 35893 21023 3 1216.679649 406.5674 Tudor-interacting repair regulator protein OS=Homo sapiens OX=9606 GN=NUDT16L1 PE=1 SV=1 5.32 3409.1 - 732516 - - - -0.5688 - 1.851 0.414 - 127.5 1 2 0 -0.0007 11 0 0 0 4.32E+06 5.73E+06 - - - 4.9047 0.9999 221125_WJC_METTL3_EV_vs_WT_F03.21024.21024.3 0.00208 Dec-40 R.DHGLEVLGLVR.V "sp|Q9BRJ7|TIRR_HUMAN,sp|Q96DE0|NUD16_HUMAN,tr|K7EIN2|K7EIN2_HUMAN" 3 1206.6721 0.75 35894 21024 3 1206.670453 403.2313 Tudor-interacting repair regulator protein OS=Homo sapiens OX=9606 GN=NUDT16L1 PE=1 SV=1 5.32 3409.2 - 583321 - - - -1.3409 - 2.225 0.432 - 239.7 1 2 0 -0.0016 11 0 0 0 4.32E+06 5.73E+06 - - - 5.6279 0.9857 221125_WJC_METTL3_EV_vs_WT_F03.21025.21025.4 0.149 Nov-84 R.LLLHLEELQMEHDIR.H "sp|Q9HCE1|MOV10_HUMAN,tr|Q5JR04|Q5JR04_HUMAN" 2 1887.9877 -1 35895 21025 4 1887.989433 473.0042 Helicase MOV-10 OS=Homo sapiens OX=9606 GN=MOV10 PE=1 SV=2 4.8 3409.3 - 531535 - - - 0.9349 - 1.825 0.184 - 92.1 1 2 0 0.0018 15 0 0 0 0.00E+00 0.00E+00 - - - 1.0423 1 221125_WJC_METTL3_EV_vs_WT_F03.21026.21026.2 1.55E-06 15/32 K.LGVQVVITDPEKLDQIR.Q "sp|P17987|TCPA_HUMAN,tr|F5GZ03|F5GZ03_HUMAN,tr|F5H282|F5H282_HUMAN,tr|E7EQR6|E7EQR6_HUMAN,tr|E7ERF2|E7ERF2_HUMAN" 5 1922.0837 0.44 35896 21026 2 1922.083307 962.0491 T-complex protein 1 subunit alpha OS=Homo sapiens OX=9606 GN=TCP1 PE=1 SV=1 4.56 3409.4 - 360741 - - - -0.1925 - 3.193 0.586 - 616.6 1 2 1 -0.0004 17 0 0 0 6.09E+06 1.37E+07 - - - 6.2234 1 221125_WJC_METTL3_EV_vs_WT_F03.21029.21029.2 9.79E-08 18/30 R.LQAEAQELLGYQVDPR.S sp|Q8TAE8|G45IP_HUMAN 1 1828.9319 1.71 35898 21029 2 1828.92936 915.4732 Growth arrest and DNA damage-inducible proteins-interacting protein 1 OS=Homo sapiens OX=9606 GN=GADD45GIP1 PE=1 SV=1 4.14 3409.8 - 1.70E+06 - - - -1.4036 - 3.259 0.539 - 562.3 1 2 0 -0.0026 16 0 0 0 2.08E+07 1.21E+07 - - - 5.9258 0.9999 221125_WJC_METTL3_EV_vs_WT_F03.21031.21031.2 4.09E-05 13/22 K.DVLSVAFSSDNR.Q "sp|P63244|RACK1_HUMAN,tr|H0YAM7|H0YAM7_HUMAN,tr|D6RFX4|D6RFX4_HUMAN,tr|D6RFZ9|D6RFZ9_HUMAN,tr|D6RAU2|D6RAU2_HUMAN,tr|H0YAF8|H0YAF8_HUMAN,tr|D6R9Z1|D6R9Z1_HUMAN,tr|J3KPE3|J3KPE3_HUMAN,tr|D6R9L0|D6R9L0_HUMAN,tr|D6RHH4|D6RHH4_HUMAN,tr|E9PD14|E9PD14_HUMAN,tr|H0Y8W2|H0Y8W2_HUMAN" 12 1308.631 1.18 35899 21031 2 1308.630397 655.3228 Receptor of activated protein C kinase 1 OS=Homo sapiens OX=9606 GN=RACK1 PE=1 SV=3 4.21 3410 - 2.90E+06 - - - -0.4562 - 2.621 0.534 - 779.8 1 2 0 -0.0006 12 0 0 0 7.07E+07 6.01E+07 - - - 5.5202 1 221125_WJC_METTL3_EV_vs_WT_F03.21034.21034.3 3.98E-08 18/56 K.SQLLK[136.11]DPQVLFAGYK[136.11].V "sp|Q9H1A7|RPB1C_HUMAN,sp|P52435|RPB11_HUMAN,sp|Q9GZM3|RPB1B_HUMAN,tr|F6S314|F6S314_HUMAN,tr|A0A0B4J2F8|A0A0B4J2F8_HUMAN,tr|E2QRJ6|E2QRJ6_HUMAN,tr|A6NFM0|A6NFM0_HUMAN" 7 1721.9687 1.02 35902 21034 3 1721.969005 574.9968 DNA-directed RNA polymerase II subunit RPB11-b2 OS=Homo sapiens OX=9606 GN=POLR2J3 PE=1 SV=1 8.22 3410.2 - 1.71E+06 - - - 0.1731 - 3.411 0.62 - 441.8 1 2 1 0.0003 15 0 0 0 1.68E+07 1.65E+07 - - - 8.654 0.9995 221125_WJC_METTL3_EV_vs_WT_F03.21035.21035.3 0.00205 Dec-48 R.GHTAEILDFALSK.D "sp|Q13685|AAMP_HUMAN,tr|H7C0R2|H7C0R2_HUMAN,tr|C9JG97|C9JG97_HUMAN,tr|C9JEH3|C9JEH3_HUMAN" 4 1400.73 1.25 35903 21035 3 1400.725558 467.9173 Angio-associated migratory cell protein OS=Homo sapiens OX=9606 GN=AAMP PE=1 SV=2 5.32 3410.3 - 1.58E+06 - - - -3.1569 - 1.97 0.415 - 165.2 1 2 0 -0.0044 13 0 0 0 1.59E+07 1.27E+07 - - - 5.004 0.9999 221125_WJC_METTL3_EV_vs_WT_F03.21036.21036.2 2.77E-06 16/28 K.AFVSGLLIGQC[160.03]SSQK.D sp|Q5SWX8|ODR4_HUMAN 1 1593.8185 1.27 35904 21036 2 1593.817188 797.9165 Protein odr-4 homolog OS=Homo sapiens OX=9606 GN=ODR4 PE=1 SV=1 8.27 3410.4 - 1.53E+06 - - - -0.8094 - 2.965 0.5 - 658.2 1 2 0 -0.0013 15 0 0 0 1.21E+07 9.51E+06 - - - 5.4057 1 221125_WJC_METTL3_EV_vs_WT_F03.21037.21037.2 7.14E-06 17/32 K.LGVQVVITDPEK[136.11]LDQIR[166.11].Q "sp|P17987|TCPA_HUMAN,tr|F5GZ03|F5GZ03_HUMAN,tr|F5H282|F5H282_HUMAN,tr|E7EQR6|E7EQR6_HUMAN,tr|E7ERF2|E7ERF2_HUMAN" 5 1940.1061 0.44 35905 21037 2 1940.104805 971.0603 T-complex protein 1 subunit alpha OS=Homo sapiens OX=9606 GN=TCP1 PE=1 SV=1 4.56 3410.5 - 1.41E+06 - - - -0.6917 - 3.335 0.528 - 662.3 1 2 1 -0.0013 17 0 0 0 6.09E+06 1.37E+07 - - - 5.9016 0.9999 221125_WJC_METTL3_EV_vs_WT_F03.21038.21038.2 5.54E-07 16/26 R.VVLVNNILQNAQER.L sp|O95295|SNAPN_HUMAN 1 1608.8948 2.19 35906 21038 2 1608.89693 805.4547 SNARE-associated protein Snapin OS=Homo sapiens OX=9606 GN=SNAPIN PE=1 SV=1 5.97 3410.7 - 918361 - - - 1.3525 - 3.101 0.509 - 901 1 2 0 0.0022 14 0 0 0 1.02E+07 4.67E+06 - - - 5.6398 0.9909 221125_WJC_METTL3_EV_vs_WT_F03.21042.21042.2 0.00313 13/30 R.EALATLKPQAGLIVPQ.A "sp|Q9UMS4|PRP19_HUMAN,tr|F5GY56|F5GY56_HUMAN,tr|F5H2I0|F5H2I0_HUMAN" 3 1647.956 1.68 35910 21042 2 1647.956397 824.9853 Pre-mRNA-processing factor 19 OS=Homo sapiens OX=9606 GN=PRPF19 PE=1 SV=1 6.1 3411.2 - 566252 - - - 0.267 - 2.462 0.441 - 254.8 1 1 0 0.0004 16 0 0 0 7.70E+06 4.57E+06 - - - 4.5132 0.9999 221125_WJC_METTL3_EV_vs_WT_F03.21045.21045.2 9.38E-06 14/36 K.SMLQATAEANNLAAVAGAR[166.11].D "sp|Q8NHH9|ATLA2_HUMAN,tr|B5MCN0|B5MCN0_HUMAN" 2 1867.945 -1 35913 21045 2 1867.947315 934.9798 Atlastin-2 OS=Homo sapiens OX=9606 GN=ATL2 PE=1 SV=2 5.72 3411.6 - 387777 - - - 1.2581 - 2.651 0.527 - 544 1 2 0 0.0023 19 0 0 0 0.00E+00 0.00E+00 - - - 5.3296 0.9997 221125_WJC_METTL3_EV_vs_WT_F03.21046.21046.2 3.85E-05 15/32 R.AIVAIENPADVSVISSR[166.11].N "sp|P08865|RSSA_HUMAN,tr|C9J9K3|C9J9K3_HUMAN,tr|A0A0C4DG17|A0A0C4DG17_HUMAN,tr|F8WD59|F8WD59_HUMAN" 4 1749.95 0.68 35914 21046 2 1749.954132 875.9823 40S ribosomal protein SA OS=Homo sapiens OX=9606 GN=RPSA PE=1 SV=4 4.37 3411.7 - 367352 - - - 2.3418 - 3.045 0.478 - 721.1 1 2 0 0.0041 17 0 0 0 1.44E+07 2.10E+07 - - - 5.3078 1 221125_WJC_METTL3_EV_vs_WT_F03.21049.21049.3 1.16E-11 22/64 R.VDLPATSVVITFHNEAR[166.11].S sp|Q10471|GALT2_HUMAN 1 1877.9875 1.39 35915 21049 3 1877.988305 627.0031 Polypeptide N-acetylgalactosaminyltransferase 2 OS=Homo sapiens OX=9606 GN=GALNT2 PE=1 SV=1 5.32 3412.1 - 6.21E+06 - - - 0.4382 - 4.077 0.585 - 931.5 1 2 0 0.0008 17 0 0 0 8.89E+07 6.40E+07 - - - 8.6123 1 221125_WJC_METTL3_EV_vs_WT_F03.21051.21051.3 3.18E-10 22/80 R.LGGLTQAPGNPVLAVQINQDK[136.11].N "sp|P26368|U2AF2_HUMAN,tr|K7ENG2|K7ENG2_HUMAN" 2 2140.1732 1.03 35917 21051 3 2140.171781 714.3983 Splicing factor U2AF 65 kDa subunit OS=Homo sapiens OX=9606 GN=U2AF2 PE=1 SV=4 5.84 3412.2 - 3.43E+06 - - - -0.6476 - 4.091 0.514 - 667.2 1 2 0 -0.0014 21 0 0 0 1.88E+07 1.82E+07 - - - 7.6477 0.9997 221125_WJC_METTL3_EV_vs_WT_F03.21054.21054.3 4.94E-05 Oct-60 R.ENLATVEGNFASIDER.M "sp|Q13561|DCTN2_HUMAN,tr|H0YI98|H0YI98_HUMAN,tr|A8K8J9|A8K8J9_HUMAN,tr|A0A7I2V4H4|A0A7I2V4H4_HUMAN,tr|A0A7I2V4Y9|A0A7I2V4Y9_HUMAN" 5 1763.8326 1.56 35920 21054 3 1763.837479 588.9515 Dynactin subunit 2 OS=Homo sapiens OX=9606 GN=DCTN2 PE=1 SV=4 4 3412.4 - 2.76E+06 - - - 2.7622 - 2.2 0.431 - 150 1 2 0 0.0049 16 0 0 0 1.50E+07 9.63E+06 - - - 5.3669 1 221125_WJC_METTL3_EV_vs_WT_F03.21055.21055.3 2.74E-10 20/76 R.GANLEEVNDEGYTPLMEAAR.E "sp|Q8IWZ3|ANKH1_HUMAN,tr|E9PDP5|E9PDP5_HUMAN" 2 2177.9899 3.55 35921 21055 3 2177.982156 727.0039 Ankyrin repeat and KH domain-containing protein 1 OS=Homo sapiens OX=9606 GN=ANKHD1 PE=1 SV=1 3.91 3412.5 - 1.53E+06 - - - -3.5615 - 3.794 0.683 - 327.7 1 2 0 -0.0078 20 0 0 0 1.24E+07 3.49E+06 - - - 9.3875 0.9988 221125_WJC_METTL3_EV_vs_WT_F03.21056.21056.3 0.00797 Oct-64 K.YVDTPFGK[136.11]PSDALILGK[136.11].L "sp|Q13126|MTAP_HUMAN,tr|B4DUC8|B4DUC8_HUMAN,tr|F2Z2F3|F2Z2F3_HUMAN,tr|J3QSB7|J3QSB7_HUMAN" 4 1836.0004 1 35922 21056 3 1835.999898 613.0074 S-methyl-5'-thioadenosine phosphorylase OS=Homo sapiens OX=9606 GN=MTAP PE=1 SV=2 5.96 3412.5 - 1.50E+06 - - - -0.274 - 1.835 0.278 - 58.9 1 2 0 -0.0005 17 0 0 0 8.69E+06 8.73E+06 - - - 3.1729 1 221125_WJC_METTL3_EV_vs_WT_F03.21057.21057.2 2.95E-08 17/30 K.C[160.03]MLFSSGTVQLTTTSR[166.11].A "sp|Q8IWS0|PHF6_HUMAN,tr|Q5JRC6|Q5JRC6_HUMAN,tr|A0A0D9SGE8|A0A0D9SGE8_HUMAN" 3 1797.8629 0.47 35923 21057 2 1797.863071 899.9387 PHD finger protein 6 OS=Homo sapiens OX=9606 GN=PHF6 PE=1 SV=1 8.25 3412.6 - 1.49E+06 - - - 0.109 - 3.317 0.726 - 979.2 1 2 0 0.0002 16 0 0 0 5.17E+06 1.09E+07 - - - 7.3511 1 221125_WJC_METTL3_EV_vs_WT_F03.21058.21058.3 1.46E-07 20/72 K.LGDVGMAELC[160.03]PGLLHPSSR.L "sp|P13489|RINI_HUMAN,tr|H0YCR7|H0YCR7_HUMAN" 2 2007.987 3.06 35924 21058 3 2007.985836 670.3363 Ribonuclease inhibitor OS=Homo sapiens OX=9606 GN=RNH1 PE=1 SV=2 5.32 3412.8 - 1.29E+06 - - - -0.5882 - 2.987 0.498 - 425.8 1 2 0 -0.0012 19 0 0 0 1.51E+07 4.92E+06 - - - 6.7803 0.9999 221125_WJC_METTL3_EV_vs_WT_F03.21059.21059.2 0.000126 26-Dec R.NDLYYNTITNFSEK.D "sp|Q14527|HLTF_HUMAN,tr|A0A0C4DGA6|A0A0C4DGA6_HUMAN" 2 1720.7944 1.16 35925 21059 2 1720.791928 861.4045 Helicase-like transcription factor OS=Homo sapiens OX=9606 GN=HLTF PE=1 SV=2 4.37 3412.9 - 1.29E+06 - - - -1.4546 - 2.741 0.513 - 415.6 1 2 0 -0.0025 14 0 0 0 2.22E+07 1.91E+07 - - - 5.3596 1 221125_WJC_METTL3_EV_vs_WT_F03.21060.21060.3 5.69E-07 16/52 R.VVLVNNILQNAQER.L sp|O95295|SNAPN_HUMAN 1 1608.8948 2.18 35926 21060 3 1608.895123 537.3055 SNARE-associated protein Snapin OS=Homo sapiens OX=9606 GN=SNAPIN PE=1 SV=1 5.97 3413 - 1.15E+06 - - - 0.2293 - 3.03 0.529 - 394.4 1 2 0 0.0004 14 0 0 0 7.82E+06 3.58E+06 - - - 7.3838 0.9987 221125_WJC_METTL3_EV_vs_WT_F03.21062.21062.3 5.63E-05 15/52 R.EFDLTKEEDLAALR.H "sp|O60313|OPA1_HUMAN,tr|A0A2R8YD53|A0A2R8YD53_HUMAN,tr|C9JMB8|C9JMB8_HUMAN,tr|A0A2R8YE54|A0A2R8YE54_HUMAN,tr|A0A2R8YDM2|A0A2R8YDM2_HUMAN,tr|E5KLJ9|E5KLJ9_HUMAN,tr|A0A2R8Y4Q3|A0A2R8Y4Q3_HUMAN,tr|A0A2R8Y3X5|A0A2R8Y3X5_HUMAN,tr|A0A2R8YGE5|A0A2R8YGE5_HUMAN,tr|A0A2R8Y4G4|A0A2R8Y4G4_HUMAN,tr|A0A2R8YE78|A0A2R8YE78_HUMAN" 11 1648.8308 1.51 35928 21062 3 1648.836427 550.6175 "Dynamin-like 120 kDa protein, mitochondrial OS=Homo sapiens OX=9606 GN=OPA1 PE=1 SV=3" 4.18 3413.3 - 1.13E+06 - - - 3.403 - 2.613 0.425 - 245.9 1 2 1 0.0056 14 0 0 0 4.42E+06 2.93E+06 - - - 5.8293 0.9999 221125_WJC_METTL3_EV_vs_WT_F03.21063.21063.2 1.15E-07 19/36 R.ILSAENIPNLPPGGGLAGK[136.11].R "sp|O75688|PPM1B_HUMAN,tr|B8ZZF0|B8ZZF0_HUMAN,tr|A0A3B3IS24|A0A3B3IS24_HUMAN,tr|C9JIR6|C9JIR6_HUMAN" 4 1825.0189 4.45 35929 21063 2 1825.020461 913.5167 Protein phosphatase 1B OS=Homo sapiens OX=9606 GN=PPM1B PE=1 SV=1 6 3413.4 - 1.11E+06 - - - 0.8559 - 2.934 0.529 - 552.7 1 2 0 0.0016 19 0 0 0 5.87E+07 1.32E+07 - - - 5.594 1 221125_WJC_METTL3_EV_vs_WT_F03.21065.21065.2 5.70E-10 18/30 R.TIQTAESLGVPYEQWK.L sp|O60825|F262_HUMAN 1 1848.9258 2.32 35931 21065 2 1848.926339 925.4702 "6-phosphofructo-2-kinase\fructose-2,6-bisphosphatase 2 OS=Homo sapiens OX=9606 GN=PFKFB2 PE=1 SV=2" 4.53 3413.7 - 997273 - - - 0.3029 - 3.261 0.562 - 746.1 1 2 0 0.0006 16 0 0 0 1.34E+07 5.77E+06 - - - 6.0978 1 221125_WJC_METTL3_EV_vs_WT_F03.21066.21066.2 6.02E-06 20/38 R.GANLEEVNDEGYTPLMEAAR.E "sp|Q8IWZ3|ANKH1_HUMAN,tr|E9PDP5|E9PDP5_HUMAN" 2 2177.9899 1.74 35932 21066 2 2177.989599 1090.0022 Ankyrin repeat and KH domain-containing protein 1 OS=Homo sapiens OX=9606 GN=ANKHD1 PE=1 SV=1 3.91 3413.8 - 898449 - - - -0.1442 - 4.294 0.664 - 1184.6 1 2 0 -0.0003 20 0 0 0 1.22E+07 6.98E+06 - - - 7.5278 1 221125_WJC_METTL3_EV_vs_WT_F03.21067.21067.3 1.60E-07 13/44 K.DVLSVAFSSDNR[166.11].Q "sp|P63244|RACK1_HUMAN,tr|H0YAM7|H0YAM7_HUMAN,tr|D6RFX4|D6RFX4_HUMAN,tr|D6RFZ9|D6RFZ9_HUMAN,tr|D6RAU2|D6RAU2_HUMAN,tr|H0YAF8|H0YAF8_HUMAN,tr|D6R9Z1|D6R9Z1_HUMAN,tr|J3KPE3|J3KPE3_HUMAN,tr|D6R9L0|D6R9L0_HUMAN,tr|D6RHH4|D6RHH4_HUMAN,tr|E9PD14|E9PD14_HUMAN,tr|H0Y8W2|H0Y8W2_HUMAN" 12 1318.6393 2.1 35933 21067 3 1318.637712 440.5537 Receptor of activated protein C kinase 1 OS=Homo sapiens OX=9606 GN=RACK1 PE=1 SV=3 4.21 3413.9 - 889970 - - - -1.177 - 2.442 0.549 - 182.7 1 2 0 -0.0016 12 0 0 0 1.69E+07 8.04E+06 - - - 7.1351 0.9557 221125_WJC_METTL3_EV_vs_WT_F03.21068.21068.2 8.46E-05 13/24 K.QLDDLKVELSQLR.V "sp|P42766|RL35_HUMAN,tr|F2Z388|F2Z388_HUMAN" 2 1555.857 0.82 35934 21068 2 1555.865848 778.9358 60S ribosomal protein L35 OS=Homo sapiens OX=9606 GN=RPL35 PE=1 SV=2 4.56 3414 - 835734 - - - 5.7049 - 2.205 0.499 - 541.7 1 2 1 0.0089 13 0 0 0 5.25E+06 6.43E+06 - - - 4.7533 0.9999 221125_WJC_METTL3_EV_vs_WT_F03.21071.21071.2 0.00155 22-Nov K.DVLSVAFSSDNR[166.11].Q "sp|P63244|RACK1_HUMAN,tr|H0YAM7|H0YAM7_HUMAN,tr|D6RFX4|D6RFX4_HUMAN,tr|D6RFZ9|D6RFZ9_HUMAN,tr|D6RAU2|D6RAU2_HUMAN,tr|H0YAF8|H0YAF8_HUMAN,tr|D6R9Z1|D6R9Z1_HUMAN,tr|J3KPE3|J3KPE3_HUMAN,tr|D6R9L0|D6R9L0_HUMAN,tr|D6RHH4|D6RHH4_HUMAN,tr|E9PD14|E9PD14_HUMAN,tr|H0Y8W2|H0Y8W2_HUMAN" 12 1318.6393 1.17 35936 21071 2 1318.639805 660.3269 Receptor of activated protein C kinase 1 OS=Homo sapiens OX=9606 GN=RACK1 PE=1 SV=3 4.21 3414.3 - 8.61E+06 - - - 0.4103 - 2.527 0.518 - 505.7 1 2 0 0.0005 12 0 0 0 7.07E+07 6.04E+07 - - - 5.306 1 221125_WJC_METTL3_EV_vs_WT_F03.21072.21072.2 2.68E-11 13/28 R.GFAFVTFDDHDSVDK.L "sp|Q32P51|RA1L2_HUMAN,sp|P09651|ROA1_HUMAN,tr|A0A7I2YQX9|A0A7I2YQX9_HUMAN,tr|F8VZ49|F8VZ49_HUMAN,tr|A0A7I2V3R8|A0A7I2V3R8_HUMAN,tr|F8VTQ5|F8VTQ5_HUMAN,tr|F8W6I7|F8W6I7_HUMAN,tr|H0YH80|H0YH80_HUMAN,tr|A0A7I2V2L6|A0A7I2V2L6_HUMAN,tr|A0A7I2V3W0|A0A7I2V3W0_HUMAN,tr|A0A7I2V5U9|A0A7I2V5U9_HUMAN,tr|A0A2R8Y4L2|A0A2R8Y4L2_HUMAN" 12 1698.7526 1.16 35937 21072 2 1698.750913 850.3836 Heterogeneous nuclear ribonucleoprotein A1-like 2 OS=Homo sapiens OX=9606 GN=HNRNPA1L2 PE=2 SV=2 4.13 3414.4 - 1.15E+07 - - - -0.9731 - 2.91 0.676 - 425.1 1 2 0 -0.0017 15 0 0 0 6.38E+07 5.48E+07 - - - 6.6595 0.9998 221125_WJC_METTL3_EV_vs_WT_F03.21074.21074.2 6.32E-07 28-Oct R.GFAFVTFDDHDSVDK[136.11].L "sp|Q32P51|RA1L2_HUMAN,sp|P09651|ROA1_HUMAN,tr|A0A7I2YQX9|A0A7I2YQX9_HUMAN,tr|F8VZ49|F8VZ49_HUMAN,tr|A0A7I2V3R8|A0A7I2V3R8_HUMAN,tr|F8VTQ5|F8VTQ5_HUMAN,tr|F8W6I7|F8W6I7_HUMAN,tr|H0YH80|H0YH80_HUMAN,tr|A0A7I2V2L6|A0A7I2V2L6_HUMAN,tr|A0A7I2V3W0|A0A7I2V3W0_HUMAN,tr|A0A7I2V5U9|A0A7I2V5U9_HUMAN,tr|A0A2R8Y4L2|A0A2R8Y4L2_HUMAN" 12 1706.7668 1.16 35939 21074 2 1706.763735 854.3907 Heterogeneous nuclear ribonucleoprotein A1-like 2 OS=Homo sapiens OX=9606 GN=HNRNPA1L2 PE=2 SV=2 4.13 3414.4 - 8.27E+06 - - - -1.7759 - 2.642 0.566 - 248.9 1 2 0 -0.003 15 0 0 0 6.34E+07 5.48E+07 - - - 5.6091 1 221125_WJC_METTL3_EV_vs_WT_F03.21076.21076.2 2.96E-10 15/28 R.YINENLIVNTDELGR[166.11].D "sp|P17987|TCPA_HUMAN,tr|F5H136|F5H136_HUMAN,tr|F5H7Y1|F5H7Y1_HUMAN,tr|E7ERF2|E7ERF2_HUMAN" 4 1771.898 0.32 35941 21076 2 1771.897763 886.9563 T-complex protein 1 subunit alpha OS=Homo sapiens OX=9606 GN=TCP1 PE=1 SV=1 4.14 3414.5 - 6.49E+06 - - - -0.1326 - 3.122 0.65 - 669 1 2 0 -0.0002 15 0 0 0 1.32E+07 4.07E+07 - - - 6.6408 1 221125_WJC_METTL3_EV_vs_WT_F03.21078.21078.3 8.14E-07 21/68 K.FITHAPPGEFNEVFNDVR.L sp|P52907|CAZA1_HUMAN 1 2088.0065 1.34 35943 21078 3 2088.008383 697.0094 F-actin-capping protein subunit alpha-1 OS=Homo sapiens OX=9606 GN=CAPZA1 PE=1 SV=3 4.65 3414.6 - 3.84E+06 - - - 0.9071 - 3.151 0.563 - 433.5 1 2 0 0.0019 18 0 0 0 6.89E+07 5.16E+07 - - - 7.6743 1 221125_WJC_METTL3_EV_vs_WT_F03.21079.21079.3 2.85E-06 14/60 R.NLVPEEADEHLFALEK.L sp|Q8WUX2|CHAC2_HUMAN 1 1852.9207 2.69 35944 21079 3 1852.919482 618.6475 Glutathione-specific gamma-glutamylcyclotransferase 2 OS=Homo sapiens OX=9606 GN=CHAC2 PE=1 SV=1 4.25 3414.7 - 3.53E+06 - - - -0.6541 - 2.526 0.498 - 196.3 1 2 0 -0.0012 16 0 0 0 1.75E+07 6.53E+06 - - - 6.4695 1 221125_WJC_METTL3_EV_vs_WT_F03.21080.21080.3 2.86E-06 25/68 K.FITHAPPGEFNEVFNDVR[166.11].L sp|P52907|CAZA1_HUMAN 1 2098.0148 1.33 35945 21080 3 2098.01423 700.3455 F-actin-capping protein subunit alpha-1 OS=Homo sapiens OX=9606 GN=CAPZA1 PE=1 SV=3 4.65 3414.7 - 3.28E+06 - - - -0.2521 - 3.485 0.57 - 744.7 1 2 0 -0.0005 18 0 0 0 6.78E+07 5.11E+07 - - - 8.0036 1 221125_WJC_METTL3_EV_vs_WT_F03.21081.21081.3 1.29E-05 16/56 K.NAEVRPPFTYASLIR.Q "sp|Q9H334|FOXP1_HUMAN,tr|A0A3B3IRW5|A0A3B3IRW5_HUMAN,tr|G5E965|G5E965_HUMAN,tr|A0A3B3IRS5|A0A3B3IRS5_HUMAN,tr|A0A3B3IST0|A0A3B3IST0_HUMAN,tr|A0A3B3IT14|A0A3B3IT14_HUMAN,tr|C9J0F0|C9J0F0_HUMAN,tr|A0A3B3IUB6|A0A3B3IUB6_HUMAN,tr|H0Y882|H0Y882_HUMAN,tr|A0A3B3IT66|A0A3B3IT66_HUMAN,tr|A0A3B3IS87|A0A3B3IS87_HUMAN,tr|A0A0B4J2F3|A0A0B4J2F3_HUMAN,tr|A0A3B3IST6|A0A3B3IST6_HUMAN" 13 1732.9261 3.24 35946 21081 3 1732.926874 578.6493 Forkhead box protein P1 OS=Homo sapiens OX=9606 GN=FOXP1 PE=1 SV=1 8.75 3414.8 - 3.11E+06 - - - 0.4732 - 2.832 0.466 - 334.6 1 2 0 0.0008 15 0 0 0 7.19E+07 2.22E+07 - - - 6.4515 1 221125_WJC_METTL3_EV_vs_WT_F03.21083.21083.3 1.60E-09 20/76 R.IVITGDADIDHDQVLVQAIK.E "sp|P11171|EPB41_HUMAN,tr|A0A3B3ITP0|A0A3B3ITP0_HUMAN,tr|A0A2U3TZH6|A0A2U3TZH6_HUMAN,tr|A0A2R8Y7Y3|A0A2R8Y7Y3_HUMAN,tr|A0A2R8YD30|A0A2R8YD30_HUMAN" 5 2162.1583 0.75 35948 21083 3 2162.1586 721.7267 Protein 4.1 OS=Homo sapiens OX=9606 GN=EPB41 PE=1 SV=4 4.13 3414.9 - 2.33E+06 - - - 0.1392 - 3.841 0.66 - 273.8 1 2 0 0.0003 20 0 0 0 8.48E+06 1.14E+07 - - - 9.163 1 221125_WJC_METTL3_EV_vs_WT_F03.21084.21084.3 4.80E-07 18/76 R.VPINDVLAEDK[136.11]ILEGTETTK[136.11].Y "sp|P82650|RT22_HUMAN,tr|G5E9W7|G5E9W7_HUMAN,tr|A0A7P0MKV3|A0A7P0MKV3_HUMAN,tr|H7C5F2|H7C5F2_HUMAN,tr|H7C5H3|H7C5H3_HUMAN" 5 2200.1809 1.67 35949 21084 3 2200.180122 734.4009 "28S ribosomal protein S22, mitochondrial OS=Homo sapiens OX=9606 GN=MRPS22 PE=1 SV=1" 4.18 3415 - 1.93E+06 - - - -0.3741 - 3.367 0.594 - 301.5 1 2 1 -0.0008 20 0 0 0 1.75E+07 1.05E+07 - - - 8.1075 1 221125_WJC_METTL3_EV_vs_WT_F03.21085.21085.2 1.37E-06 13/24 F.AFVTFDDHDSVDK.L "sp|Q32P51|RA1L2_HUMAN,sp|P09651|ROA1_HUMAN,tr|A0A7I2YQX9|A0A7I2YQX9_HUMAN,tr|F8VZ49|F8VZ49_HUMAN,tr|A0A7I2V3R8|A0A7I2V3R8_HUMAN,tr|F8VTQ5|F8VTQ5_HUMAN,tr|F8W6I7|F8W6I7_HUMAN,tr|H0YH80|H0YH80_HUMAN,tr|A0A7I2V2L6|A0A7I2V2L6_HUMAN,tr|A0A7I2V3W0|A0A7I2V3W0_HUMAN,tr|A0A7I2V5U9|A0A7I2V5U9_HUMAN,tr|A0A2R8Y4L2|A0A2R8Y4L2_HUMAN" 12 1494.6627 0.58 35950 21085 2 1494.662196 748.3386 Heterogeneous nuclear ribonucleoprotein A1-like 2 OS=Homo sapiens OX=9606 GN=HNRNPA1L2 PE=2 SV=2 4.13 3415.1 - 1.92E+06 - - - -0.3292 - 2.638 0.631 - 399.3 1 1 0 -0.0005 13 0 0 0 8.72E+06 1.50E+07 - - - 6.191 1 221125_WJC_METTL3_EV_vs_WT_F03.21086.21086.2 1.21E-12 21/38 R.GANLEEVNDEGYTPLMEAAR[166.11].E "sp|Q8IWZ3|ANKH1_HUMAN,tr|E9PDP5|E9PDP5_HUMAN" 2 2187.9982 1.74 35951 21086 2 2188.993673 1095.0064 Ankyrin repeat and KH domain-containing protein 1 OS=Homo sapiens OX=9606 GN=ANKHD1 PE=1 SV=1 3.91 3415.2 - 1.69E+06 - - - 454.9775 - 3.921 0.721 - 1463.1 1 2 0 0.9955 20 0 0 0 1.22E+07 6.98E+06 - - - 7.4129 0.9999 221125_WJC_METTL3_EV_vs_WT_F03.21087.21087.3 0.014 16/48 R.QLTLSGIYAHITK[136.11].H sp|P85037|FOXK1_HUMAN 1 1451.8228 0.16 35952 21087 3 1451.823195 484.9482 Forkhead box protein K1 OS=Homo sapiens OX=9606 GN=FOXK1 PE=1 SV=1 8.6 3415.3 - 1.59E+06 - - - 0.2962 - 2.588 0.361 - 408.4 1 2 0 0.0004 13 0 0 0 4.52E+06 2.92E+07 - - - 5.1428 1 221125_WJC_METTL3_EV_vs_WT_F03.21088.21088.2 4.53E-09 19/32 R.AIVAIENPADVSVISSR.N "sp|P08865|RSSA_HUMAN,tr|C9J9K3|C9J9K3_HUMAN,tr|A0A0C4DG17|A0A0C4DG17_HUMAN,tr|F8WD59|F8WD59_HUMAN" 4 1739.9418 0.69 35953 21088 2 1739.939096 870.9782 40S ribosomal protein SA OS=Homo sapiens OX=9606 GN=RPSA PE=1 SV=4 4.37 3415.4 - 1.48E+06 - - - -1.5334 - 3.683 0.493 - 1230 1 2 0 -0.0027 17 0 0 0 1.44E+07 2.07E+07 - - - 5.8867 1 221125_WJC_METTL3_EV_vs_WT_F03.21089.21089.2 1.28E-06 17/30 K.C[160.03]MLFSSGTVQLTTTSR.A "sp|Q8IWS0|PHF6_HUMAN,tr|Q5JRC6|Q5JRC6_HUMAN,tr|A0A0D9SGE8|A0A0D9SGE8_HUMAN" 3 1787.8546 0.45 35954 21089 2 1787.856645 894.9346 PHD finger protein 6 OS=Homo sapiens OX=9606 GN=PHF6 PE=1 SV=1 8.25 3415.5 - 1.04E+06 - - - 1.141 - 3.242 0.655 - 955.9 1 2 0 0.002 16 0 0 0 4.88E+06 1.09E+07 - - - 6.7699 1 221125_WJC_METTL3_EV_vs_WT_F03.21091.21091.2 2.59E-10 20/30 R.TIQTAESLGVPYEQWK[136.11].L sp|O60825|F262_HUMAN 1 1856.94 2.32 35955 21091 2 1856.93894 929.4773 "6-phosphofructo-2-kinase\fructose-2,6-bisphosphatase 2 OS=Homo sapiens OX=9606 GN=PFKFB2 PE=1 SV=2" 4.53 3415.7 - 1.01E+06 - - - -0.5595 - 3.563 0.54 - 858.4 1 2 0 -0.001 16 0 0 0 1.34E+07 5.77E+06 - - - 6.1529 0.9991 221125_WJC_METTL3_EV_vs_WT_F03.21092.21092.3 0.00309 15/60 R.AGIHPLSLGSVLSASR.R sp|Q969S2|NEIL2_HUMAN 1 1563.8733 0.03 35956 21092 3 1563.874016 522.2984 Endonuclease 8-like 2 OS=Homo sapiens OX=9606 GN=NEIL2 PE=1 SV=3 9.8 3415.9 - 830002 - - - 0.4642 - 1.807 0.302 - 159.7 1 2 0 0.0007 16 0 0 0 4.12E+06 1.47E+08 - - - 3.4249 0.9998 221125_WJC_METTL3_EV_vs_WT_F03.21094.21094.3 0.000595 13/60 R.TIQTAESLGVPYEQWK.L sp|O60825|F262_HUMAN 1 1848.9258 1.2 35958 21094 3 1848.925769 617.3159 "6-phosphofructo-2-kinase\fructose-2,6-bisphosphatase 2 OS=Homo sapiens OX=9606 GN=PFKFB2 PE=1 SV=2" 4.53 3416 - 3.00E+06 - - - -0.0054 - 2.112 0.375 - 171.6 1 2 0 0 16 0 0 0 1.20E+07 1.00E+07 - - - 4.6392 1 221125_WJC_METTL3_EV_vs_WT_F03.21095.21095.3 1.11E-05 Dec-60 K.GDDLLPAGTEDYIHIR[166.11].L "sp|P41567|EIF1_HUMAN,sp|O60739|EIF1B_HUMAN,tr|K7EM18|K7EM18_HUMAN" 3 1793.8823 1.2 35959 21095 3 1793.882315 598.9681 Eukaryotic translation initiation factor 1 OS=Homo sapiens OX=9606 GN=EIF1 PE=1 SV=1 4.22 3416 - 2.71E+06 - - - -0.0184 - 2.514 0.49 - 227.6 1 2 0 0 16 0 0 0 1.16E+07 9.68E+06 - - - 6.3684 0.9999 221125_WJC_METTL3_EV_vs_WT_F03.21096.21096.3 6.40E-05 16/40 R.EWLEVLEDTKR.A sp|Q8IYI6|EXOC8_HUMAN 1 1416.7249 1.97 35960 21096 3 1416.72782 473.2489 Exocyst complex component 8 OS=Homo sapiens OX=9606 GN=EXOC8 PE=1 SV=2 4.41 3416.1 - 2.49E+06 - - - 2.0646 - 3.092 0.445 - 618.8 1 2 0 0.0029 11 0 0 0 4.51E+07 2.29E+07 - - - 6.7073 0.9982 221125_WJC_METTL3_EV_vs_WT_F03.21097.21097.3 0.00182 Aug-56 R.YINENLIVNTDELGR.D "sp|P17987|TCPA_HUMAN,tr|F5H136|F5H136_HUMAN,tr|F5H7Y1|F5H7Y1_HUMAN,tr|E7ERF2|E7ERF2_HUMAN" 4 1761.8897 0.38 35961 21097 3 1761.89109 588.3039 T-complex protein 1 subunit alpha OS=Homo sapiens OX=9606 GN=TCP1 PE=1 SV=1 4.14 3416.1 - 2.26E+06 - - - 0.773 - 1.976 0.232 - 81.8 1 2 0 0.0014 15 0 0 0 7.08E+06 1.87E+07 - - - 2.9034 0.9948 221125_WJC_METTL3_EV_vs_WT_F03.21099.21099.2 9.43E-07 30-Oct R.VQDDEVGDGTTSVTVL.A "sp|P78371|TCPB_HUMAN,tr|F8VQ14|F8VQ14_HUMAN,tr|F5GWF6|F5GWF6_HUMAN" 3 1633.7683 - 35963 21099 2 1633.7685 817.8914 T-complex protein 1 subunit beta OS=Homo sapiens OX=9606 GN=CCT2 PE=1 SV=4 3.37 3416.3 - 2.07E+06 - - - 0.1371 - 2.197 0.621 - 260.9 1 1 0 0.0002 16 0 0 0 - - - - - 5.5627 1 221125_WJC_METTL3_EV_vs_WT_F03.21100.21100.3 3.10E-07 20/76 R.IVITGDADIDHDQVLVQAIK[136.11].E "sp|P11171|EPB41_HUMAN,tr|A0A3B3ITP0|A0A3B3ITP0_HUMAN,tr|A0A2U3TZH6|A0A2U3TZH6_HUMAN,tr|A0A2R8Y7Y3|A0A2R8Y7Y3_HUMAN,tr|A0A2R8YD30|A0A2R8YD30_HUMAN" 5 2170.1725 0.73 35964 21100 3 2170.172168 724.3981 Protein 4.1 OS=Homo sapiens OX=9606 GN=EPB41 PE=1 SV=4 4.13 3416.4 - 2.02E+06 - - - -0.1525 - 3.253 0.544 - 248.4 1 2 0 -0.0003 20 0 0 0 8.64E+06 1.19E+07 - - - 7.4667 1 221125_WJC_METTL3_EV_vs_WT_F03.21102.21102.3 6.21E-06 18/52 K.GAVSAEQVIAGFNR[166.11].L sp|Q9UHV9|PFD2_HUMAN 1 1427.7396 2.83 35966 21102 3 1427.739146 476.9205 Prefoldin subunit 2 OS=Homo sapiens OX=9606 GN=PFDN2 PE=1 SV=1 6 3416.7 - 1.37E+06 - - - -0.3509 - 2.924 0.495 - 406.9 1 2 0 -0.0005 14 0 0 0 3.23E+07 1.14E+07 - - - 6.91 0.9998 221125_WJC_METTL3_EV_vs_WT_F03.21106.21106.2 8.59E-09 13/28 R.MATEVAADALGEEWK.G "sp|P62753|RS6_HUMAN,tr|A2A3R5|A2A3R5_HUMAN,tr|A2A3R7|A2A3R7_HUMAN" 3 1619.7501 -1 35970 21106 2 1619.75346 810.8823 40S ribosomal protein S6 OS=Homo sapiens OX=9606 GN=RPS6 PE=1 SV=1 4 3417.2 - 992999 - - - 2.0602 - 3.185 0.518 - 598 1 2 0 0.0033 15 0 0 0 0.00E+00 0.00E+00 - - - 5.714 1 221125_WJC_METTL3_EV_vs_WT_F03.21107.21107.3 0.000198 14/44 K.KNAAIAVLEELK.K "sp|O95793|STAU1_HUMAN,tr|Q5JW30|Q5JW30_HUMAN,tr|Q5JW28|Q5JW28_HUMAN" 3 1297.7606 2.67 35971 21107 3 1297.759382 433.5941 Double-stranded RNA-binding protein Staufen homolog 1 OS=Homo sapiens OX=9606 GN=STAU1 PE=1 SV=2 6.14 3417.3 - 954393 - - - -0.9016 - 3.066 0.465 - 450 1 2 0 -0.0012 12 0 0 0 3.84E+06 1.44E+06 - - - 6.8295 0.9998 221125_WJC_METTL3_EV_vs_WT_F03.21109.21109.3 1.50E-07 17/52 R.VSYFAVFDGHGGIR[166.11].A "sp|Q9H0C8|ILKAP_HUMAN,tr|E9PC05|E9PC05_HUMAN" 2 1533.7604 -1 35973 21109 3 1533.767347 512.2607 Integrin-linked kinase-associated serine\threonine phosphatase 2C OS=Homo sapiens OX=9606 GN=ILKAP PE=1 SV=1 6.71 3417.6 - 539440 - - - 4.5405 - 3.314 0.49 - 312.1 1 2 0 0.007 14 0 0 0 0.00E+00 0.00E+00 - - - 7.1852 0.9998 221125_WJC_METTL3_EV_vs_WT_F03.21112.21112.3 0.00357 Nov-40 R.TILQHLSEAWR[166.11].C "sp|Q6P2Q9|PRP8_HUMAN,tr|I3L0J9|I3L0J9_HUMAN" 2 1362.7284 1.35 35975 21112 3 1362.726993 455.2501 Pre-mRNA-processing-splicing factor 8 OS=Homo sapiens OX=9606 GN=PRPF8 PE=1 SV=2 6.41 3417.9 - 632556 - - - -0.9987 - 2.172 0.351 - 134.6 1 2 0 -0.0014 11 0 0 0 3.33E+06 2.46E+06 - - - 4.6564 0.9975 221125_WJC_METTL3_EV_vs_WT_F03.21113.21113.2 0.0518 30-Aug R.VVVSGLPPSGSWQDLK[136.11].D "sp|Q07955|SRSF1_HUMAN,tr|J3KTL2|J3KTL2_HUMAN,tr|J3KSR8|J3KSR8_HUMAN" 3 1675.9025 1.81 35976 21113 2 1675.903741 838.9585 Serine\arginine-rich splicing factor 1 OS=Homo sapiens OX=9606 GN=SRSF1 PE=1 SV=2 5.81 3418 - 331915 - - - 0.7572 - 1.485 0.236 - 85.4 1 2 0 0.0013 16 0 0 0 8.44E+06 4.67E+06 - - - 1.7558 1 221125_WJC_METTL3_EV_vs_WT_F03.21114.21114.2 7.47E-09 16/26 K.GAVSAEQVIAGFNR.L sp|Q9UHV9|PFD2_HUMAN 1 1417.7314 0.84 35977 21114 2 1417.731566 709.873 Prefoldin subunit 2 OS=Homo sapiens OX=9606 GN=PFDN2 PE=1 SV=1 6 3418.1 - 4.36E+06 - - - 0.1333 - 3.21 0.588 - 996.6 1 2 0 0.0002 14 0 0 0 2.85E+07 3.39E+07 - - - 6.3106 1 221125_WJC_METTL3_EV_vs_WT_F03.21117.21117.3 9.82E-09 17/72 R.VIEVSHWGNIAVEENVDLK.H "sp|P04843|RPN1_HUMAN,tr|B7Z4L4|B7Z4L4_HUMAN" 2 2150.1008 2.1 35980 21117 3 2150.10248 717.7075 Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit 1 OS=Homo sapiens OX=9606 GN=RPN1 PE=1 SV=1 4.4 3418.2 - 2.32E+06 - - - 0.7888 - 3.323 0.568 - 313 1 2 0 0.0017 19 0 0 0 8.68E+06 4.13E+06 - - - 7.8225 1 221125_WJC_METTL3_EV_vs_WT_F03.21122.21122.2 0.000143 14/22 R.AADFIDQALAQK[136.11].N "sp|P51452|DUS3_HUMAN,tr|K7ES89|K7ES89_HUMAN,tr|K7ELG5|K7ELG5_HUMAN" 3 1297.6758 1.91 35985 21122 2 1297.67468 649.8452 Dual specificity protein phosphatase 3 OS=Homo sapiens OX=9606 GN=DUSP3 PE=1 SV=1 4.21 3418.8 - 1.45E+06 - - - -0.8369 - 2.827 0.535 - 801.6 1 2 0 -0.0011 12 0 0 0 1.63E+07 8.56E+06 - - - 5.7265 0.9998 221125_WJC_METTL3_EV_vs_WT_F03.21123.21123.3 4.46E-06 14/72 R.VIEVSHWGNIAVEENVDLK[136.11].H "sp|P04843|RPN1_HUMAN,tr|B7Z4L4|B7Z4L4_HUMAN" 2 2158.115 2.1 35986 21123 3 2158.120291 720.3789 Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit 1 OS=Homo sapiens OX=9606 GN=RPN1 PE=1 SV=1 4.4 3418.9 - 1.43E+06 - - - 2.4591 - 2.471 0.432 - 170 1 2 0 0.0053 19 0 0 0 8.68E+06 4.13E+06 - - - 5.5774 1 221125_WJC_METTL3_EV_vs_WT_F03.21124.21124.3 0.0421 18/52 K.SDIDEIVLVGGSTR[166.11].L "sp|P11021|BIP_HUMAN,tr|A0A7P0TB36|A0A7P0TB36_HUMAN" 2 1469.7601 0.52 35987 21124 3 1469.759396 490.9273 Endoplasmic reticulum chaperone BiP OS=Homo sapiens OX=9606 GN=HSPA5 PE=1 SV=2 4.03 3419 - 1.17E+06 - - - -0.4844 - 2.982 0.416 - 377.5 1 2 0 -0.0007 14 0 0 0 5.33E+06 1.02E+07 - - - 6.0814 1 221125_WJC_METTL3_EV_vs_WT_F03.21125.21125.2 1.09E-08 14/26 R.TEGSLEDWDIAVQK[136.11].T "sp|Q15020|SART3_HUMAN,tr|A0A499FI31|A0A499FI31_HUMAN" 2 1597.7715 3.07 35988 21125 2 1597.771596 799.893 Squamous cell carcinoma antigen recognized by T-cells 3 OS=Homo sapiens OX=9606 GN=SART3 PE=1 SV=1 3.92 3419.1 - 1.16E+06 - - - 0.0494 - 3.077 0.616 - 635.7 1 2 0 0.0001 14 0 0 0 2.24E+07 7.30E+06 - - - 6.4113 0.9993 221125_WJC_METTL3_EV_vs_WT_F03.21126.21126.3 0.000385 17/56 R.GFAFVTFDDHDTVDK[136.11].L "sp|P51991|ROA3_HUMAN,tr|A0A7I2V5D8|A0A7I2V5D8_HUMAN,tr|A0A7I2V2R3|A0A7I2V2R3_HUMAN,tr|A0A7I2V4J6|A0A7I2V4J6_HUMAN,tr|A0A7I2V4G0|A0A7I2V4G0_HUMAN,tr|A0A7I2V402|A0A7I2V402_HUMAN" 6 1720.7824 1.28 35989 21126 3 1720.792934 574.6014 Heterogeneous nuclear ribonucleoprotein A3 OS=Homo sapiens OX=9606 GN=HNRNPA3 PE=1 SV=2 4.13 3419.2 - 1.14E+06 - - - 6.1123 - 2.854 0.523 - 241.6 1 2 0 0.0105 15 0 0 0 3.18E+08 2.48E+08 - - - 7.1045 0.9998 221125_WJC_METTL3_EV_vs_WT_F03.21127.21127.3 7.93E-06 Nov-40 R.TILQHLSEAWR.C "sp|Q6P2Q9|PRP8_HUMAN,tr|I3L0J9|I3L0J9_HUMAN" 2 1352.7201 1.54 35990 21127 3 1352.719144 451.914 Pre-mRNA-processing-splicing factor 8 OS=Homo sapiens OX=9606 GN=PRPF8 PE=1 SV=2 6.41 3419.4 - 676914 - - - -0.6949 - 2.187 0.331 - 165.5 1 2 0 -0.0009 11 0 0 0 6.41E+06 4.17E+06 - - - 4.4531 0.9997 221125_WJC_METTL3_EV_vs_WT_F03.21128.21128.2 0.000198 20-Oct R.ADLEMQIESLK.E sp|P02533|K1C14_HUMAN 1 1275.6381 999 35991 21128 2 1275.636295 638.8263 "Keratin, type I cytoskeletal 14 OS=Homo sapiens OX=9606 GN=KRT14 PE=1 SV=4" 4.14 3419.5 - 609991 - - - -1.3789 - 2.149 0.427 - 315.2 1 2 0 -0.0018 11 0 0 0 3.08E+06 0.00E+00 - - - 4.2638 1 221125_WJC_METTL3_EV_vs_WT_F03.21133.21133.3 0.00181 Dec-44 K.GISDLAQHYLMR[166.11].A "sp|P49368|TCPG_HUMAN,tr|B4DUR8|B4DUR8_HUMAN" 2 1412.711 0.19 35995 21133 3 1412.710707 471.9109 T-complex protein 1 subunit gamma OS=Homo sapiens OX=9606 GN=CCT3 PE=1 SV=4 6.74 3419.9 - 1.98E+07 - - - -0.1996 - 2.45 0.452 - 156.5 1 2 0 -0.0003 12 0 0 0 6.09E+07 3.21E+08 - - - 6.0631 1 221125_WJC_METTL3_EV_vs_WT_F03.21134.21134.2 5.97E-08 17/26 K.SDIDEIVLVGGSTR[166.11].L "sp|P11021|BIP_HUMAN,tr|A0A7P0TB36|A0A7P0TB36_HUMAN" 2 1469.7601 0.56 35996 21134 2 1469.760517 735.8873 Endoplasmic reticulum chaperone BiP OS=Homo sapiens OX=9606 GN=HSPA5 PE=1 SV=2 4.03 3420 - 7.68E+06 - - - 0.2783 - 2.956 0.629 - 1193.4 1 2 0 0.0004 14 0 0 0 3.14E+07 5.57E+07 - - - 6.4065 1 221125_WJC_METTL3_EV_vs_WT_F03.21135.21135.3 6.69E-09 13/84 K.SISISVAGGGGGFGAAGGFGGR.G sp|P35908|K22E_HUMAN 1 1837.9071 46.81 35997 21135 3 1837.907954 613.643 "Keratin, type II cytoskeletal 2 epidermal OS=Homo sapiens OX=9606 GN=KRT2 PE=1 SV=2" 9.47 3420 - 5.56E+06 - - - 0.4592 - 2.921 0.608 - 182.2 1 2 0 0.0008 22 0 0 0 2.72E+08 5.81E+06 - - - 7.8597 1 221125_WJC_METTL3_EV_vs_WT_F03.21136.21136.2 7.37E-07 17/26 K.GAVSAEQVIAGFNR[166.11].L sp|Q9UHV9|PFD2_HUMAN 1 1427.7396 1.06 35998 21136 2 1427.737706 714.8771 Prefoldin subunit 2 OS=Homo sapiens OX=9606 GN=PFDN2 PE=1 SV=1 6 3420.1 - 5.53E+06 - - - -1.3595 - 3.378 0.622 - 1179.9 1 2 0 -0.0019 14 0 0 0 3.69E+07 3.47E+07 - - - 6.6892 1 221125_WJC_METTL3_EV_vs_WT_F03.21137.21137.2 3.43E-13 18/42 K.SISISVAGGGGGFGAAGGFGGR.G sp|P35908|K22E_HUMAN 1 1837.9071 32.95 35999 21137 2 1837.907212 919.9608 "Keratin, type II cytoskeletal 2 epidermal OS=Homo sapiens OX=9606 GN=KRT2 PE=1 SV=2" 9.47 3420.1 - 5.26E+06 - - - 0.0555 - 3.62 0.708 - 608.5 1 2 0 0.0001 22 0 0 0 3.56E+08 1.08E+07 - - - 7.4331 1 221125_WJC_METTL3_EV_vs_WT_F03.21138.21138.2 9.87E-07 26-Dec R.TEGSLEDWDIAVQK.T "sp|Q15020|SART3_HUMAN,tr|A0A499FI31|A0A499FI31_HUMAN" 2 1589.7573 3.07 36000 21138 2 1589.75335 795.8859 Squamous cell carcinoma antigen recognized by T-cells 3 OS=Homo sapiens OX=9606 GN=SART3 PE=1 SV=1 3.92 3420.2 - 4.03E+06 - - - -2.4953 - 2.885 0.639 - 442.6 1 2 0 -0.004 14 0 0 0 2.24E+07 7.30E+06 - - - 6.4182 0.9999 221125_WJC_METTL3_EV_vs_WT_F03.21139.21139.2 6.55E-06 16/22 K.GISDLAQHYLMR[166.11].A "sp|P49368|TCPG_HUMAN,tr|B4DUR8|B4DUR8_HUMAN" 2 1412.711 0.19 36001 21139 2 1412.712224 707.3628 T-complex protein 1 subunit gamma OS=Homo sapiens OX=9606 GN=CCT3 PE=1 SV=4 6.74 3420.2 - 3.47E+06 - - - 0.8742 - 3.121 0.497 - 858.2 1 2 0 0.0012 12 0 0 0 1.28E+07 6.71E+07 - - - 5.7061 0.9999 221125_WJC_METTL3_EV_vs_WT_F03.21140.21140.3 0.000333 13/44 K.GISDLAQHYLMR.A "sp|P49368|TCPG_HUMAN,tr|B4DUR8|B4DUR8_HUMAN" 2 1402.7027 0.19 36002 21140 3 1402.699353 468.5748 T-complex protein 1 subunit gamma OS=Homo sapiens OX=9606 GN=CCT3 PE=1 SV=4 6.74 3420.3 - 3.43E+06 - - - -2.3997 - 2.541 0.471 - 200.7 1 2 0 -0.0034 12 0 0 0 6.09E+07 3.21E+08 - - - 6.3752 1 221125_WJC_METTL3_EV_vs_WT_F03.21141.21141.3 6.96E-07 14/60 R.K[136.11]EPVYLSGYGVELAIK[136.11].S sp|Q9NYU2|UGGG1_HUMAN 1 1780.9946 0.24 36003 21141 3 1780.99547 594.6721 UDP-glucose:glycoprotein glucosyltransferase 1 OS=Homo sapiens OX=9606 GN=UGGT1 PE=1 SV=3 6.14 3420.3 - 2.33E+06 - - - 0.4952 - 2.506 0.533 - 182 1 2 0 0.0009 16 0 0 0 4.34E+06 1.78E+07 - - - 6.8394 1 221125_WJC_METTL3_EV_vs_WT_F03.21143.21143.3 7.25E-08 21/76 K.TPLSTGGTLAFVSPSLAVHK.S sp|Q86YP4|P66A_HUMAN 1 1982.0837 1.5 36005 21143 3 1982.08396 661.7018 Transcriptional repressor p66-alpha OS=Homo sapiens OX=9606 GN=GATAD2A PE=1 SV=1 8.44 3420.5 - 2.21E+06 - - - 0.1428 - 3.598 0.584 - 395.8 1 2 0 0.0003 20 0 0 0 5.67E+07 3.77E+07 - - - 8.1572 1 221125_WJC_METTL3_EV_vs_WT_F03.21144.21144.3 4.35E-09 23/76 K.TPLSTGGTLAFVSPSLAVHK[136.11].S sp|Q86YP4|P66A_HUMAN 1 1990.0979 1.5 36006 21144 3 1990.098361 664.3732 Transcriptional repressor p66-alpha OS=Homo sapiens OX=9606 GN=GATAD2A PE=1 SV=1 8.44 3420.6 - 1.87E+06 - - - 0.2432 - 4.045 0.598 - 846.1 1 2 0 0.0005 20 0 0 0 5.67E+07 3.77E+07 - - - 8.5973 0.9986 221125_WJC_METTL3_EV_vs_WT_F03.21146.21146.3 4.35E-08 25/84 N.VHGALAPLAIPSAAAAAAAAGR.L "sp|P26599|PTBP1_HUMAN,tr|A0A0U1RRM4|A0A0U1RRM4_HUMAN,tr|A6NLN1|A6NLN1_HUMAN,tr|A0A087WU68|A0A087WU68_HUMAN,tr|A0A7I2V621|A0A7I2V621_HUMAN,tr|A0A087WTS6|A0A087WTS6_HUMAN,tr|K7EK45|K7EK45_HUMAN" 7 1926.0799 1.1 36008 21146 3 1926.08167 643.0339 Polypyrimidine tract-binding protein 1 OS=Homo sapiens OX=9606 GN=PTBP1 PE=1 SV=1 9.73 3420.8 - 1.33E+06 - - - 0.9039 - 3.82 0.552 - 815.1 1 1 0 0.0017 22 0 0 0 7.84E+06 7.13E+06 - - - 7.8713 1 221125_WJC_METTL3_EV_vs_WT_F03.21149.21149.2 3.80E-10 18/28 R.C[160.03]GNQAAIMELDDTLK[136.11].Y "sp|P67775|PP2AA_HUMAN,sp|P62714|PP2AB_HUMAN,tr|H0YC23|H0YC23_HUMAN,tr|H0YBN9|H0YBN9_HUMAN" 4 1685.7844 1.02 36011 21149 2 1685.787151 843.8995 Serine\threonine-protein phosphatase 2A catalytic subunit alpha isoform OS=Homo sapiens OX=9606 GN=PPP2CA PE=1 SV=1 4.03 3421.1 - 1.02E+06 - - - 1.6277 - 3.646 0.708 - 1610.4 1 2 0 0.0027 15 0 0 0 2.20E+07 2.16E+07 - - - 7.4499 1 221125_WJC_METTL3_EV_vs_WT_F03.21152.21152.2 8.29E-08 21/36 R.ILSAENIPNLPPGGGLAGK.R "sp|O75688|PPM1B_HUMAN,tr|B8ZZF0|B8ZZF0_HUMAN,tr|A0A3B3IS24|A0A3B3IS24_HUMAN,tr|C9JIR6|C9JIR6_HUMAN" 4 1817.0047 4.31 36013 21152 2 1817.002738 909.5096 Protein phosphatase 1B OS=Homo sapiens OX=9606 GN=PPM1B PE=1 SV=1 6 3421.5 - 2.83E+06 - - - -1.0792 - 3.394 0.538 - 755.9 1 2 0 -0.002 19 0 0 0 5.54E+07 1.29E+07 - - - 6.0184 0.9998 221125_WJC_METTL3_EV_vs_WT_F03.21153.21153.3 0.000466 Dec-72 R.ILSAENIPNLPPGGGLAGK[136.11].R "sp|O75688|PPM1B_HUMAN,tr|B8ZZF0|B8ZZF0_HUMAN,tr|A0A3B3IS24|A0A3B3IS24_HUMAN,tr|C9JIR6|C9JIR6_HUMAN" 4 1825.0189 4.07 36014 21153 3 1825.019545 609.3469 Protein phosphatase 1B OS=Homo sapiens OX=9606 GN=PPM1B PE=1 SV=1 6 3421.6 - 1.45E+06 - - - 0.354 - 2.048 0.376 - 148 1 2 0 0.0006 19 0 0 0 6.10E+07 1.50E+07 - - - 4.493 0.9942 221125_WJC_METTL3_EV_vs_WT_F03.21154.21154.3 3.21E-07 15/56 R.GFAFVTFDDHDTVDK.L "sp|P51991|ROA3_HUMAN,tr|A0A7I2V5D8|A0A7I2V5D8_HUMAN,tr|A0A7I2V2R3|A0A7I2V2R3_HUMAN,tr|A0A7I2V4J6|A0A7I2V4J6_HUMAN,tr|A0A7I2V4G0|A0A7I2V4G0_HUMAN,tr|A0A7I2V402|A0A7I2V402_HUMAN" 6 1712.7682 1.29 36015 21154 3 1712.782753 571.93 Heterogeneous nuclear ribonucleoprotein A3 OS=Homo sapiens OX=9606 GN=HNRNPA3 PE=1 SV=2 4.13 3421.6 - 8.29E+06 - - - 8.4874 - 2.716 0.412 - 211.1 1 2 0 0.0145 15 0 0 0 3.17E+08 2.47E+08 - - - 5.7365 0.9977 221125_WJC_METTL3_EV_vs_WT_F03.21155.21155.3 8.89E-08 21/76 R.QLSEPC[160.03]LYPEPLPALRPTPR.P sp|Q5T749|KPRP_HUMAN 1 2333.2202 129.18 36016 21155 3 2333.219732 778.7473 Keratinocyte proline-rich protein OS=Homo sapiens OX=9606 GN=KPRP PE=1 SV=1 6.14 3421.7 - 4.12E+06 - - - -0.1954 - 2.81 0.525 - 405.6 1 1 0 -0.0005 20 0 0 0 1.02E+08 7.92E+05 - - - 6.8996 0.9951 221125_WJC_METTL3_EV_vs_WT_F03.21157.21157.3 0.000274 Nov-56 K.NAEVR[166.11]PPFTYASLIR[166.11].Q "sp|Q9H334|FOXP1_HUMAN,tr|A0A3B3IRW5|A0A3B3IRW5_HUMAN,tr|G5E965|G5E965_HUMAN,tr|A0A3B3IRS5|A0A3B3IRS5_HUMAN,tr|A0A3B3IST0|A0A3B3IST0_HUMAN,tr|A0A3B3IT14|A0A3B3IT14_HUMAN,tr|C9J0F0|C9J0F0_HUMAN,tr|A0A3B3IUB6|A0A3B3IUB6_HUMAN,tr|H0Y882|H0Y882_HUMAN,tr|A0A3B3IT66|A0A3B3IT66_HUMAN,tr|A0A3B3IS87|A0A3B3IS87_HUMAN,tr|A0A0B4J2F3|A0A0B4J2F3_HUMAN,tr|A0A3B3IST6|A0A3B3IST6_HUMAN" 13 1752.9426 2.85 36018 21157 3 1752.946289 585.3215 Forkhead box protein P1 OS=Homo sapiens OX=9606 GN=FOXP1 PE=1 SV=1 8.75 3421.8 - 1.56E+06 - - - 2.1079 - 2.308 0.179 - 163.6 1 2 0 0.0037 15 0 0 0 3.02E+07 1.06E+07 - - - 2.7171 0.9998 221125_WJC_METTL3_EV_vs_WT_F03.21158.21158.2 0.000348 24-Nov K.LQIWDTAGQESFR.S "sp|P61019|RAB2A_HUMAN,sp|Q8WUD1|RAB2B_HUMAN,tr|A0A3B3ITL1|A0A3B3ITL1_HUMAN,tr|E9PKL7|E9PKL7_HUMAN" 4 1549.7525 1.16 36019 21158 2 1549.754498 775.8835 Ras-related protein Rab-2A OS=Homo sapiens OX=9606 GN=RAB2A PE=1 SV=1 4.37 3421.9 - 1.50E+06 - - - 1.2854 - 2.433 0.439 - 341.7 1 2 0 0.002 13 0 0 0 1.99E+07 1.71E+07 - - - 4.5648 0.9907 221125_WJC_METTL3_EV_vs_WT_F03.21160.21160.2 3.40E-05 24-Oct K.VHYENNSPFLTIT.S "sp|P04843|RPN1_HUMAN,tr|B7Z4L4|B7Z4L4_HUMAN" 2 1533.7464 - 36021 21160 2 1533.747004 767.8805 Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit 1 OS=Homo sapiens OX=9606 GN=RPN1 PE=1 SV=1 5.24 3422.2 - 1.34E+06 - - - 0.4212 - 2.133 0.481 - 330.4 1 1 0 0.0006 13 0 0 0 - - - - - 4.5377 1 221125_WJC_METTL3_EV_vs_WT_F03.21161.21161.2 4.40E-07 15/30 R.ELLYGGTSPTAETILK.N "sp|O95793|STAU1_HUMAN,tr|Q5JW30|Q5JW30_HUMAN" 2 1691.8982 1.9 36022 21161 2 1691.900048 846.9564 Double-stranded RNA-binding protein Staufen homolog 1 OS=Homo sapiens OX=9606 GN=STAU1 PE=1 SV=2 4.53 3422.3 - 1.24E+06 - - - 1.1112 - 2.922 0.584 - 553.3 1 2 0 0.0019 16 0 0 0 5.57E+06 2.93E+06 - - - 5.9901 1 221125_WJC_METTL3_EV_vs_WT_F03.21164.21164.3 9.90E-08 16/56 R.C[160.03]GNQAAIMELDDTLK.Y "sp|P67775|PP2AA_HUMAN,sp|P62714|PP2AB_HUMAN,tr|H0YC23|H0YC23_HUMAN,tr|H0YBN9|H0YBN9_HUMAN" 4 1677.7702 0.75 36025 21164 3 1677.76977 560.264 Serine\threonine-protein phosphatase 2A catalytic subunit alpha isoform OS=Homo sapiens OX=9606 GN=PPP2CA PE=1 SV=1 4.03 3422.7 - 392509 - - - -0.2605 - 2.942 0.569 - 324 1 2 0 -0.0004 15 0 0 0 3.89E+06 5.21E+06 - - - 7.6994 0.979 221125_WJC_METTL3_EV_vs_WT_F03.21165.21165.3 0.19 Oct-48 K.FNFGEEEFKFPPK.D "sp|Q92499|DDX1_HUMAN,tr|A0A7I2V2M5|A0A7I2V2M5_HUMAN,tr|A0A087X2G1|A0A087X2G1_HUMAN,tr|A0A7I2V430|A0A7I2V430_HUMAN,tr|A0A7I2V421|A0A7I2V421_HUMAN,tr|A0A7I2V4F0|A0A7I2V4F0_HUMAN,tr|A0A7I2V5X8|A0A7I2V5X8_HUMAN,tr|A0A7I2V4J3|A0A7I2V4J3_HUMAN,tr|A0A087WZ71|A0A087WZ71_HUMAN,tr|A0A7I2YQ77|A0A7I2YQ77_HUMAN" 10 1614.7718 3.82 36026 21165 3 1614.770329 539.2646 ATP-dependent RNA helicase DDX1 OS=Homo sapiens OX=9606 GN=DDX1 PE=1 SV=2 4.79 3422.9 - 315141 - - - -0.9388 - 1.337 0.265 - 61.5 1 2 1 -0.0015 13 0 0 0 2.18E+06 5.71E+05 - - - 2.2815 1 221125_WJC_METTL3_EV_vs_WT_F03.21173.21173.2 6.34E-13 15/28 R.C[160.03]GNQAAIMELDDTLK.Y "sp|P67775|PP2AA_HUMAN,sp|P62714|PP2AB_HUMAN,tr|H0YC23|H0YC23_HUMAN,tr|H0YBN9|H0YBN9_HUMAN" 4 1677.7702 1.01 36032 21173 2 1677.771061 839.8924 Serine\threonine-protein phosphatase 2A catalytic subunit alpha isoform OS=Homo sapiens OX=9606 GN=PPP2CA PE=1 SV=1 4.03 3423.6 - 2.49E+06 - - - 0.509 - 3.127 0.716 - 942.3 1 2 0 0.0009 15 0 0 0 2.20E+07 2.19E+07 - - - 7.132 0.9993 221125_WJC_METTL3_EV_vs_WT_F03.21174.21174.2 8.84E-06 13/24 K.LQIWDTAGQESFR[166.11].S "sp|P61019|RAB2A_HUMAN,sp|Q8WUD1|RAB2B_HUMAN,tr|A0A3B3ITL1|A0A3B3ITL1_HUMAN,tr|E9PKL7|E9PKL7_HUMAN" 4 1559.7608 1.35 36033 21174 2 1559.754911 780.8877 Ras-related protein Rab-2A OS=Homo sapiens OX=9606 GN=RAB2A PE=1 SV=1 4.37 3423.7 - 1.73E+06 - - - -3.7602 - 2.566 0.536 - 453.9 1 2 0 -0.0059 13 0 0 0 2.16E+07 1.61E+07 - - - 5.4166 1 221125_WJC_METTL3_EV_vs_WT_F03.21176.21176.2 1.83E-10 18/32 K.TVNELQNLSSAEVVVPR.D sp|O00425|IF2B3_HUMAN 1 1853.9847 1.78 36035 21176 2 1853.985397 927.9996 Insulin-like growth factor 2 mRNA-binding protein 3 OS=Homo sapiens OX=9606 GN=IGF2BP3 PE=1 SV=2 4.53 3423.9 - 1.31E+06 - - - 0.3808 - 3.821 0.658 - 939.5 1 2 0 0.0007 17 0 0 0 4.64E+07 2.60E+07 - - - 7.1965 1 221125_WJC_METTL3_EV_vs_WT_F03.21177.21177.2 8.34E-12 18/30 K.SVVDYNAYAGVWSQDK.W "sp|Q7Z739|YTHD3_HUMAN,tr|A0A087X0Q1|A0A087X0Q1_HUMAN,tr|A0A024R7W5|A0A024R7W5_HUMAN,tr|A0A087WY31|A0A087WY31_HUMAN" 4 1800.8319 0.77 36036 21177 2 1800.82964 901.4232 YTH domain-containing family protein 3 OS=Homo sapiens OX=9606 GN=YTHDF3 PE=1 SV=1 4.21 3424.1 - 1.24E+06 - - - -1.2433 - 3.285 0.678 - 986.4 1 2 0 -0.0022 16 0 0 0 6.92E+06 8.96E+06 - - - 6.9721 1 221125_WJC_METTL3_EV_vs_WT_F03.21178.21178.2 9.86E-09 16/30 K.SVVDYNAYAGVWSQDK[136.11].W "sp|Q7Z739|YTHD3_HUMAN,tr|A0A087X0Q1|A0A087X0Q1_HUMAN,tr|A0A024R7W5|A0A024R7W5_HUMAN,tr|A0A087WY31|A0A087WY31_HUMAN" 4 1808.8461 0.77 36037 21178 2 1808.849595 905.4303 YTH domain-containing family protein 3 OS=Homo sapiens OX=9606 GN=YTHDF3 PE=1 SV=1 4.21 3424.2 - 1.23E+06 - - - 1.9438 - 2.885 0.62 - 744.4 1 2 0 0.0035 16 0 0 0 6.92E+06 8.96E+06 - - - 6.2241 1 221125_WJC_METTL3_EV_vs_WT_F03.21179.21179.2 4.13E-10 20/32 K.TVNELQNLSSAEVVVPR[166.11].D sp|O00425|IF2B3_HUMAN 1 1863.993 1.78 36038 21179 2 1863.987712 933.0038 Insulin-like growth factor 2 mRNA-binding protein 3 OS=Homo sapiens OX=9606 GN=IGF2BP3 PE=1 SV=2 4.53 3424.3 - 991682 - - - -2.816 - 3.965 0.666 - 1543.6 1 2 0 -0.0052 17 0 0 0 4.64E+07 2.60E+07 - - - 7.3451 1 221125_WJC_METTL3_EV_vs_WT_F03.21182.21182.2 6.52E-06 14/26 K.TSDIFEADIANDVK[136.11].S sp|O94763|RMP_HUMAN 1 1544.745 1.42 36041 21182 2 1544.739594 773.3798 Unconventional prefoldin RPB5 interactor 1 OS=Homo sapiens OX=9606 GN=URI1 PE=1 SV=3 3.84 3424.7 - 720086 - - - -3.4789 - 2.97 0.565 - 592.7 1 2 0 -0.0054 14 0 0 0 8.90E+06 6.26E+06 - - - 5.9441 0.9989 221125_WJC_METTL3_EV_vs_WT_F03.21183.21183.3 2.71E-05 14/44 R.AAGGLHLLPWSR.G sp|Q8IYS2|K2013_HUMAN 1 1276.704 1.28 36042 21183 3 1276.699591 426.5753 Uncharacterized protein KIAA2013 OS=Homo sapiens OX=9606 GN=KIAA2013 PE=1 SV=1 9.8 3424.9 - 708224 - - - -3.4848 - 2.442 0.317 - 310.8 1 2 0 -0.0044 12 0 0 0 1.30E+07 1.02E+07 - - - 4.5478 0.9998 221125_WJC_METTL3_EV_vs_WT_F03.21186.21186.2 7.90E-09 26-Dec K.TGTAYTFFTPNNIK[136.11].Q "sp|P17844|DDX5_HUMAN,tr|J3KTA4|J3KTA4_HUMAN,tr|A0A0G2JLI4|A0A0G2JLI4_HUMAN" 3 1581.7919 1.56 36044 21186 2 1581.789527 791.9032 Probable ATP-dependent RNA helicase DDX5 OS=Homo sapiens OX=9606 GN=DDX5 PE=1 SV=1 8.26 3425.2 - 2.14E+06 - - - -1.4743 - 2.3 0.543 - 451.8 1 2 0 -0.0023 14 0 0 0 4.06E+08 2.60E+08 - - - 5.141 0.9859 221125_WJC_METTL3_EV_vs_WT_F03.21191.21191.2 8.79E-08 24-Dec K.TPSSDVLVFDYTK.H "sp|Q09028|RBBP4_HUMAN,sp|Q16576|RBBP7_HUMAN,tr|Q5JP01|Q5JP01_HUMAN,tr|H0YF10|H0YF10_HUMAN,tr|E9PC52|E9PC52_HUMAN" 5 1470.7242 0.54 36048 21191 2 1470.711569 736.3694 Histone-binding protein RBBP4 OS=Homo sapiens OX=9606 GN=RBBP4 PE=1 SV=3 4.21 3425.6 - 3.27E+06 - - - -8.606 - 2.396 0.56 - 578.3 1 2 0 -0.0127 13 0 0 0 1.28E+08 2.37E+08 - - - 5.4158 1 221125_WJC_METTL3_EV_vs_WT_F03.21193.21193.3 3.88E-10 22/68 R.LGLEALAANHQQLFTDGR[166.11].S "sp|Q9Y2Z4|SYYM_HUMAN,tr|H0YHS6|H0YHS6_HUMAN" 2 1963.0151 1.29 36050 21193 3 1963.013162 655.3456 "Tyrosine--tRNA ligase, mitochondrial OS=Homo sapiens OX=9606 GN=YARS2 PE=1 SV=2" 5.32 3425.8 - 1.85E+06 - - - -0.9842 - 4.377 0.507 - 684.8 1 2 0 -0.0019 18 0 0 0 1.06E+07 8.23E+06 - - - 7.8683 0.9998 221125_WJC_METTL3_EV_vs_WT_F03.21194.21194.3 1.81E-06 18/64 K.R[166.11]TGAIVDVPVGEELLGR[166.11].V "sp|P25705|ATPA_HUMAN,tr|K7EQH4|K7EQH4_HUMAN,tr|K7ERX7|K7ERX7_HUMAN,tr|K7EK77|K7EK77_HUMAN,tr|K7EJP1|K7EJP1_HUMAN" 5 1800.0008 0.8 36051 21194 3 1800.005613 601.0076 "ATP synthase subunit alpha, mitochondrial OS=Homo sapiens OX=9606 GN=ATP5F1A PE=1 SV=1" 4.68 3425.9 - 1.40E+06 - - - 2.6533 - 2.807 0.387 - 411.5 1 2 0 0.0048 17 0 0 0 1.27E+07 1.59E+07 - - - 5.4608 0.9977 221125_WJC_METTL3_EV_vs_WT_F03.21195.21195.2 2.33E-06 22-Dec K.EQADFALEALAK[136.11].A "sp|Q7Z406|MYH14_HUMAN,sp|P35579|MYH9_HUMAN,tr|M0QY43|M0QY43_HUMAN" 3 1312.6754 0.51 36052 21195 2 1312.669077 657.345 Myosin-14 OS=Homo sapiens OX=9606 GN=MYH14 PE=1 SV=2 4.14 3426 - 1.36E+06 - - - -4.8413 - 2.186 0.485 - 432.1 1 2 0 -0.0064 12 0 0 0 1.30E+07 2.55E+07 - - - 4.679 0.9999 221125_WJC_METTL3_EV_vs_WT_F03.21197.21197.3 0.000271 15/44 R.AAGGLHLLPWSR[166.11].G sp|Q8IYS2|K2013_HUMAN 1 1286.7123 1.28 36054 21197 3 1286.710008 429.9114 Uncharacterized protein KIAA2013 OS=Homo sapiens OX=9606 GN=KIAA2013 PE=1 SV=1 9.8 3426.3 - 799656 - - - -1.7891 - 2.404 0.423 - 346.6 1 2 0 -0.0023 12 0 0 0 1.30E+07 1.02E+07 - - - 5.6867 0.9989 221125_WJC_METTL3_EV_vs_WT_F03.21198.21198.2 0.0649 28-Oct K.SQLIMQAEAEAASVR[166.11].M "sp|O75955|FLOT1_HUMAN,tr|A0A140T9W4|A0A140T9W4_HUMAN,tr|A0A140T9R1|A0A140T9R1_HUMAN" 3 1612.8118 0.18 36055 21198 2 1612.80983 807.4132 Flotillin-1 OS=Homo sapiens OX=9606 GN=FLOT1 PE=1 SV=3 4.53 3426.4 - 420938 - - - -1.2376 - 1.792 0.286 - 212.3 1 2 0 -0.002 15 0 0 0 1.26E+06 6.86E+06 - - - 2.5869 0.9951 221125_WJC_METTL3_EV_vs_WT_F03.21199.21199.3 0.0922 Oct-60 K.SVVDYNAYAGVWSQDK[136.11].W "sp|Q7Z739|YTHD3_HUMAN,tr|A0A087X0Q1|A0A087X0Q1_HUMAN,tr|A0A024R7W5|A0A024R7W5_HUMAN,tr|A0A087WY31|A0A087WY31_HUMAN" 4 1808.8461 1.39 36056 21199 3 1808.846131 603.956 YTH domain-containing family protein 3 OS=Homo sapiens OX=9606 GN=YTHDF3 PE=1 SV=1 4.21 3426.6 - 763938 - - - 0.0287 - 1.858 0.19 - 78.4 1 2 0 0.0001 16 0 0 0 3.90E+06 2.81E+06 - - - 2.2479 0.9902 221125_WJC_METTL3_EV_vs_WT_F03.21201.21201.2 0.000167 24-Sep R.ETNLDSLPLVDTH.S sp|P08670|VIME_HUMAN 1 1452.7096 - 36057 21201 2 1452.707873 727.3621 Vimentin OS=Homo sapiens OX=9606 GN=VIM PE=1 SV=4 4.02 3426.8 - 1.41E+07 - - - -1.2157 - 2.261 0.498 - 251.7 1 1 0 -0.0018 13 0 0 0 - - - - - 4.8125 1 221125_WJC_METTL3_EV_vs_WT_F03.21203.21203.3 0.000248 17/64 K.TVNELQNLSSAEVVVPR[166.11].D sp|O00425|IF2B3_HUMAN 1 1863.993 1.54 36059 21203 3 1863.991252 622.3383 Insulin-like growth factor 2 mRNA-binding protein 3 OS=Homo sapiens OX=9606 GN=IGF2BP3 PE=1 SV=2 4.53 3426.9 - 3.82E+06 - - - -0.9168 - 2.695 0.444 - 492.8 1 2 0 -0.0017 17 0 0 0 5.46E+07 3.55E+07 - - - 5.9943 1 221125_WJC_METTL3_EV_vs_WT_F03.21205.21205.2 1.90E-09 16/38 R.LGSAGGLGSTLGGSSYSSC[160.03]Y.S "sp|Q04695|K1C17_HUMAN,tr|K7EPJ9|K7EPJ9_HUMAN" 2 1879.8258 - 36061 21205 2 1879.822777 940.9202 "Keratin, type I cytoskeletal 17 OS=Homo sapiens OX=9606 GN=KRT17 PE=1 SV=2" 5.52 3427.1 - 3.11E+06 - - - -1.6124 - 2.924 0.692 - 361.5 1 1 0 -0.003 20 0 0 0 - - - - - 6.7891 1 221125_WJC_METTL3_EV_vs_WT_F03.21211.21211.2 2.44E-07 19/36 R.LTPSPDIIVLSDNEASSPR.S "sp|Q8WXI9|P66B_HUMAN,tr|A0A0U1RR34|A0A0U1RR34_HUMAN,tr|A0A0U1RRM1|A0A0U1RRM1_HUMAN,tr|A0A0U1RRK3|A0A0U1RRK3_HUMAN" 4 2010.0269 2.75 36067 21211 2 2010.028794 1006.0208 Transcriptional repressor p66-beta OS=Homo sapiens OX=9606 GN=GATAD2B PE=1 SV=1 4.03 3427.8 - 1.17E+06 - - - 0.9174 - 3.232 0.623 - 909.2 1 2 0 0.0018 19 0 0 0 1.91E+07 6.96E+06 - - - 6.526 0.9997 221125_WJC_METTL3_EV_vs_WT_F03.21212.21212.2 0.0871 18-Dec R.NINIGDISIK[136.11].V sp|Q92572|AP3S1_HUMAN 1 1093.6223 0.69 36068 21212 2 1093.621462 547.8184 AP-3 complex subunit sigma-1 OS=Homo sapiens OX=9606 GN=AP3S1 PE=1 SV=1 5.84 3427.9 - 1.08E+06 - - - -0.7425 - 2.196 0.345 - 392.8 1 2 0 -0.0008 10 0 0 0 1.11E+07 1.61E+07 - - - 3.7847 1 221125_WJC_METTL3_EV_vs_WT_F03.21214.21214.2 1.43E-07 19/36 R.LTPSPDIIVLSDNEASSPR[166.11].S "sp|Q8WXI9|P66B_HUMAN,tr|A0A0U1RR34|A0A0U1RR34_HUMAN,tr|A0A0U1RRM1|A0A0U1RRM1_HUMAN,tr|A0A0U1RRK3|A0A0U1RRK3_HUMAN" 4 2020.0352 2.75 36070 21214 2 2020.035662 1011.0249 Transcriptional repressor p66-beta OS=Homo sapiens OX=9606 GN=GATAD2B PE=1 SV=1 4.03 3428.2 - 648263 - - - 0.2188 - 3.137 0.593 - 907.7 1 2 0 0.0004 19 0 0 0 1.91E+07 6.96E+06 - - - 6.2315 0.9709 221125_WJC_METTL3_EV_vs_WT_F03.21216.21216.3 0.0753 Nov-48 R.ETNLDSLPLVDTH.S sp|P08670|VIME_HUMAN 1 1452.7096 - 36071 21216 3 1452.711475 485.2438 Vimentin OS=Homo sapiens OX=9606 GN=VIM PE=1 SV=4 4.02 3428.4 - 1.92E+06 - - - 1.2638 - 2.055 0.356 - 199.9 1 1 0 0.0018 13 0 0 0 - - - - - 4.4614 1 221125_WJC_METTL3_EV_vs_WT_F03.21218.21218.3 1.09E-06 16/72 R.ILSAENIPNLPPGGGLAGK.R "sp|O75688|PPM1B_HUMAN,tr|B8ZZF0|B8ZZF0_HUMAN,tr|A0A3B3IS24|A0A3B3IS24_HUMAN,tr|C9JIR6|C9JIR6_HUMAN" 4 1817.0047 4.07 36072 21218 3 1817.004978 606.6755 Protein phosphatase 1B OS=Homo sapiens OX=9606 GN=PPM1B PE=1 SV=1 6 3428.6 - 3.36E+06 - - - 0.1535 - 2.745 0.54 - 263.4 1 2 0 0.0003 19 0 0 0 3.43E+07 8.43E+06 - - - 7.0412 0.9993 221125_WJC_METTL3_EV_vs_WT_F03.21219.21219.3 0.00131 16/72 R.LAILQVGNRDDSNLYINVK.L "sp|P11586|C1TC_HUMAN,tr|F5H2F4|F5H2F4_HUMAN,tr|V9GYY3|V9GYY3_HUMAN" 3 2144.159 1.54 36073 21219 3 2144.158203 715.7269 "C-1-tetrahydrofolate synthase, cytoplasmic OS=Homo sapiens OX=9606 GN=MTHFD1 PE=1 SV=4" 5.96 3428.7 - 2.34E+06 - - - -0.3563 - 2.973 0.326 - 313.1 1 2 1 -0.0008 19 0 0 0 2.36E+07 1.53E+07 - - - 4.8512 1 221125_WJC_METTL3_EV_vs_WT_F03.21224.21224.3 9.59E-09 16/56 K.DVFFYQADDEHYIPR.A "sp|Q9NRH3|TBG2_HUMAN,sp|P23258|TBG1_HUMAN,tr|K7EIS0|K7EIS0_HUMAN,tr|A0A7P0T9G6|A0A7P0T9G6_HUMAN,tr|K7EKE5|K7EKE5_HUMAN" 5 1913.8584 0.76 36078 21224 3 1913.854061 638.9601 Tubulin gamma-2 chain OS=Homo sapiens OX=9606 GN=TUBG2 PE=2 SV=1 4.22 3429.2 - 878321 - - - -2.2818 - 2.817 0.604 - 306.9 1 2 0 -0.0044 15 0 0 0 8.07E+06 1.06E+07 - - - 7.9752 0.9998 221125_WJC_METTL3_EV_vs_WT_F03.21225.21225.3 3.82E-05 Dec-40 K.QHVTEAFQFHF.- "sp|O43175|SERA_HUMAN,tr|A0A286YF22|A0A286YF22_HUMAN,tr|A0A286YFA2|A0A286YFA2_HUMAN" 3 1389.6466 - 36079 21225 3 1389.645006 464.2228 D-3-phosphoglycerate dehydrogenase OS=Homo sapiens OX=9606 GN=PHGDH PE=1 SV=4 5.98 3429.3 - 556612 - - - -1.1363 - 2.144 0.371 - 133.7 1 2 0 -0.0016 11 0 0 0 - - - - - 4.8425 1 221125_WJC_METTL3_EV_vs_WT_F03.21234.21234.3 8.12E-08 18/68 K.VLVYNNTSIVQDEILAHR[166.11].L "sp|O15160|RPAC1_HUMAN,tr|D6RDJ3|D6RDJ3_HUMAN,tr|A0A2R8YEZ4|A0A2R8YEZ4_HUMAN,tr|H0Y723|H0Y723_HUMAN,tr|E7EQB9|E7EQB9_HUMAN,tr|A0A2R8Y5D3|A0A2R8Y5D3_HUMAN,tr|A0A2R8YEY5|A0A2R8YEY5_HUMAN,tr|A0A2R8Y8D6|A0A2R8Y8D6_HUMAN" 8 2093.1145 0.27 36086 21234 3 2093.114516 698.7121 DNA-directed RNA polymerases I and III subunit RPAC1 OS=Homo sapiens OX=9606 GN=POLR1C PE=1 SV=1 5.32 3430.3 - 2.34E+06 - - - 0.0201 - 3.277 0.556 - 407.6 1 2 0 0 18 0 0 0 5.77E+06 2.13E+07 - - - 7.6944 0.9997 221125_WJC_METTL3_EV_vs_WT_F03.21236.21236.3 9.09E-07 15/72 R.LTPSPDIIVLSDNEASSPR[166.11].S "sp|Q8WXI9|P66B_HUMAN,tr|A0A0U1RR34|A0A0U1RR34_HUMAN,tr|A0A0U1RRM1|A0A0U1RRM1_HUMAN,tr|A0A0U1RRK3|A0A0U1RRK3_HUMAN" 4 2020.0352 2.42 36088 21236 3 2020.027289 674.3523 Transcriptional repressor p66-beta OS=Homo sapiens OX=9606 GN=GATAD2B PE=1 SV=1 4.03 3430.5 - 1.51E+06 - - - -3.9262 - 3.239 0.438 - 331.6 1 2 0 -0.0079 19 0 0 0 2.14E+07 8.84E+06 - - - 6.3085 1 221125_WJC_METTL3_EV_vs_WT_F03.21237.21237.3 8.84E-06 16/72 R.VNIAFNYDMPEDSDTYLHR.V "sp|Q13838|DX39B_HUMAN,tr|H0Y400|H0Y400_HUMAN,tr|Q5STU3|Q5STU3_HUMAN,tr|A0A0G2JJZ9|A0A0G2JJZ9_HUMAN,tr|A0A140T9X3|A0A140T9X3_HUMAN" 5 2299.0215 1.59 36089 21237 3 2299.021781 767.3478 Spliceosome RNA helicase DDX39B OS=Homo sapiens OX=9606 GN=DDX39B PE=1 SV=1 4.22 3430.6 - 1.48E+06 - - - 0.1018 - 3.213 0.594 - 254.4 1 2 0 0.0002 19 0 0 0 1.21E+07 7.63E+06 - - - 8.03 0.9999 221125_WJC_METTL3_EV_vs_WT_F03.21239.21239.2 0.00153 13/28 R.LQGLSASDVTEQIIK.T sp|Q9UBB5|MBD2_HUMAN 1 1600.8672 2.49 36091 21239 2 1600.868681 801.4409 Methyl-CpG-binding domain protein 2 OS=Homo sapiens OX=9606 GN=MBD2 PE=1 SV=1 4.37 3430.8 - 1.25E+06 - - - 0.9239 - 2.774 0.493 - 463.4 1 2 0 0.0015 15 0 0 0 1.13E+07 4.52E+06 - - - 5.1903 1 221125_WJC_METTL3_EV_vs_WT_F03.21240.21240.3 1.71E-11 20/68 K.AEVIMNYHVGETVLSLQK[136.11].T sp|Q15393|SF3B3_HUMAN 1 2038.0649 1.03 36092 21240 3 2038.061749 680.3622 Splicing factor 3B subunit 3 OS=Homo sapiens OX=9606 GN=SF3B3 PE=1 SV=4 5.4 3430.9 - 1.20E+06 - - - -1.5274 - 3.846 0.538 - 433.6 1 2 0 -0.0031 18 0 0 0 2.57E+07 2.50E+07 - - - 7.8916 1 221125_WJC_METTL3_EV_vs_WT_F03.21241.21241.3 1.55E-09 17/68 K.AEVIMNYHVGETVLSLQK.T sp|Q15393|SF3B3_HUMAN 1 2030.0507 1.03 36093 21241 3 2030.053689 677.6908 Splicing factor 3B subunit 3 OS=Homo sapiens OX=9606 GN=SF3B3 PE=1 SV=4 5.4 3431.1 - 1.15E+06 - - - 1.4911 - 3.902 0.57 - 265.9 1 2 0 0.003 18 0 0 0 2.57E+07 2.50E+07 - - - 8.2843 0.9999 221125_WJC_METTL3_EV_vs_WT_F03.21242.21242.2 4.09E-05 13/22 R.QPQVAELLAEAR[166.11].R "sp|P51570|GALK1_HUMAN,tr|K7ERJ9|K7ERJ9_HUMAN,tr|K7ERN9|K7ERN9_HUMAN,tr|K7EII7|K7EII7_HUMAN" 4 1333.7229 1.9 36094 21242 2 1333.722915 667.8687 Galactokinase OS=Homo sapiens OX=9606 GN=GALK1 PE=1 SV=1 4.53 3431.2 - 1.07E+06 - - - -0.0142 - 2.274 0.507 - 615.5 1 2 0 0 12 0 0 0 2.67E+07 1.41E+07 - - - 4.9473 0.9956 221125_WJC_METTL3_EV_vs_WT_F03.21243.21243.3 0.113 Oct-52 K.IGYLNDR[166.11]VDELLEK[136.11].Y "sp|Q9H0P0|5NT3A_HUMAN,tr|X6RM59|X6RM59_HUMAN" 2 1693.9006 3.92 36095 21243 3 1693.904151 565.6408 Cytosolic 5'-nucleotidase 3A OS=Homo sapiens OX=9606 GN=NT5C3A PE=1 SV=3 4.32 3431.3 - 955407 - - - 2.1135 - 2.229 0.288 - 108.7 1 2 1 0.0036 14 0 0 0 3.05E+07 7.80E+06 - - - 3.8801 0.9998 221125_WJC_METTL3_EV_vs_WT_F03.21247.21247.2 0.00045 16/28 R.NVQAEEMVEFSSGLK.G "sp|P25705|ATPA_HUMAN,tr|K7EQH4|K7EQH4_HUMAN,tr|K7ERX7|K7ERX7_HUMAN,tr|K7EK77|K7EK77_HUMAN,tr|K7EJP1|K7EJP1_HUMAN" 5 1666.7872 9.87 36099 21247 2 1666.783721 834.4009 "ATP synthase subunit alpha, mitochondrial OS=Homo sapiens OX=9606 GN=ATP5F1A PE=1 SV=1" 4.25 3431.8 - 770180 - - - -2.1094 - 2.701 0.51 - 544.4 1 2 0 -0.0035 15 0 0 0 6.73E+06 6.82E+05 - - - 5.2496 0.9005 221125_WJC_METTL3_EV_vs_WT_F03.21248.21248.3 0.00261 Oct-52 L.KAAILPTSIFLTNK.K "sp|O14744|ANM5_HUMAN,tr|H0YJX6|H0YJX6_HUMAN" 2 1515.9025 4.1 36100 21248 3 1515.899501 506.3081 Protein arginine N-methyltransferase 5 OS=Homo sapiens OX=9606 GN=PRMT5 PE=1 SV=4 10 3432 - 662557 - - - -1.9553 - 1.715 0.333 - 82.8 1 1 0 -0.003 14 0 0 0 6.54E+06 1.60E+06 - - - 3.6853 0.9989 221125_WJC_METTL3_EV_vs_WT_F03.21249.21249.2 4.34E-07 14/34 K.EPNPPIDEVISTPGVVAR[166.11].F "sp|P52294|IMA5_HUMAN,tr|C9JWD9|C9JWD9_HUMAN,tr|C9JYI4|C9JYI4_HUMAN,tr|C9J352|C9J352_HUMAN,tr|C9J4U1|C9J4U1_HUMAN,tr|F2Z3G4|F2Z3G4_HUMAN" 6 1898.9977 1.2 36101 21249 2 1898.989309 950.5061 Importin subunit alpha-5 OS=Homo sapiens OX=9606 GN=KPNA1 PE=1 SV=3 4.14 3432.1 - 568385 - - - -4.425 - 2.496 0.592 - 374.1 1 2 0 -0.0084 18 0 0 0 3.09E+06 2.58E+06 - - - 5.6597 1 221125_WJC_METTL3_EV_vs_WT_F03.21252.21252.2 6.46E-12 13/34 R.FFQGSQEFLASASASAER[166.11].S "sp|Q7Z2W4|ZCCHV_HUMAN,tr|C9J6P4|C9J6P4_HUMAN,tr|A0A7P0T8C6|A0A7P0T8C6_HUMAN" 3 1941.9096 -1 36103 21252 2 1941.904114 971.9621 Zinc finger CCCH-type antiviral protein 1 OS=Homo sapiens OX=9606 GN=ZC3HAV1 PE=1 SV=3 4.53 3432.5 - 332306 - - - -2.8384 - 2.902 0.613 - 442 1 2 0 -0.0055 18 0 0 0 0.00E+00 0.00E+00 - - - 6.1862 1 221125_WJC_METTL3_EV_vs_WT_F03.21256.21256.3 2.92E-09 18/56 K.FNFLNPNDPYHAYYR[166.11].H sp|Q15459|SF3A1_HUMAN 1 1939.8881 1.07 36106 21256 3 1939.885964 647.6366 Splicing factor 3A subunit 1 OS=Homo sapiens OX=9606 GN=SF3A1 PE=1 SV=1 6.74 3432.9 - 3.86E+06 - - - -1.1021 - 3.233 0.605 - 551.8 1 2 0 -0.0021 15 0 0 0 3.54E+07 3.31E+07 - - - 8.3464 0.9997 221125_WJC_METTL3_EV_vs_WT_F03.21258.21258.3 4.85E-05 13/52 R.GFC[160.03]FITFKEEEPVK.K "sp|Q14103|HNRPD_HUMAN,tr|H0Y8G5|H0Y8G5_HUMAN,tr|H0YA96|H0YA96_HUMAN" 3 1729.8385 1.19 36108 21258 3 1729.838198 577.6201 Heterogeneous nuclear ribonucleoprotein D0 OS=Homo sapiens OX=9606 GN=HNRNPD PE=1 SV=1 4.79 3433 - 2.09E+06 - - - -0.2006 - 1.906 0.491 - 133.7 1 2 1 -0.0003 14 0 0 0 1.75E+07 1.46E+07 - - - 5.7282 1 221125_WJC_METTL3_EV_vs_WT_F03.21261.21261.2 7.90E-08 14/34 R.GGGGSFGYSYGGGSGGGF.S sp|P35527|K1C9_HUMAN 1 1526.6062 - 36111 21261 2 1526.610034 764.3104 "Keratin, type I cytoskeletal 9 OS=Homo sapiens OX=9606 GN=KRT9 PE=1 SV=3" 5.52 3433.4 - 1.72E+06 - - - 2.4879 - 2.445 0.634 - 378 1 1 0 0.0038 18 0 0 0 - - - - - 5.9206 1 221125_WJC_METTL3_EV_vs_WT_F03.21263.21263.3 7.82E-07 15/52 R.ASELHLLETPLVVK[136.11].K sp|Q8WYP5|ELYS_HUMAN 1 1555.9065 1.12 36113 21263 3 1555.905128 519.6428 Protein ELYS OS=Homo sapiens OX=9606 GN=AHCTF1 PE=1 SV=3 5.4 3433.6 - 1.25E+06 - - - -0.8779 - 3.19 0.565 - 306.2 1 2 0 -0.0014 14 0 0 0 1.10E+07 9.81E+06 - - - 7.9216 0.9999 221125_WJC_METTL3_EV_vs_WT_F03.21264.21264.2 1.37E-07 22-Nov R.QPQVAELLAEAR.R "sp|P51570|GALK1_HUMAN,tr|K7ERJ9|K7ERJ9_HUMAN,tr|K7ERN9|K7ERN9_HUMAN,tr|K7EII7|K7EII7_HUMAN" 4 1323.7147 1.9 36114 21264 2 1323.714137 662.8646 Galactokinase OS=Homo sapiens OX=9606 GN=GALK1 PE=1 SV=1 4.53 3433.7 - 1.25E+06 - - - -0.3981 - 2.183 0.53 - 459.9 1 2 0 -0.0005 12 0 0 0 2.67E+07 1.41E+07 - - - 5.0096 1 221125_WJC_METTL3_EV_vs_WT_F03.21265.21265.3 1.69E-07 18/52 R.ASELHLLETPLVVK.K sp|Q8WYP5|ELYS_HUMAN 1 1547.8923 1.03 36115 21265 3 1547.89179 516.9714 Protein ELYS OS=Homo sapiens OX=9606 GN=AHCTF1 PE=1 SV=3 5.4 3433.9 - 1.17E+06 - - - -0.3256 - 3.563 0.54 - 455.8 1 2 0 -0.0005 14 0 0 0 7.36E+06 7.14E+06 - - - 7.937 1 221125_WJC_METTL3_EV_vs_WT_F03.21267.21267.2 8.35E-07 17/28 M.VDVIFADVAQPDQTR[166.11].L "sp|P22087|FBRL_HUMAN,tr|M0R299|M0R299_HUMAN,tr|M0R0P1|M0R0P1_HUMAN,tr|M0QXL5|M0QXL5_HUMAN,tr|M0R2Q4|M0R2Q4_HUMAN" 5 1682.8503 0.91 36117 21267 2 1682.84423 842.4324 rRNA 2'-O-methyltransferase fibrillarin OS=Homo sapiens OX=9606 GN=FBL PE=1 SV=2 3.93 3434.1 - 1.06E+06 - - - -3.6189 - 3.31 0.579 - 1208.3 1 1 0 -0.0061 15 0 0 0 6.89E+06 7.55E+06 - - - 6.2583 1 221125_WJC_METTL3_EV_vs_WT_F03.21269.21269.3 1.24E-05 20/48 R.QLILFGGFHESTR[166.11].D "sp|Q8TBB5|KLDC4_HUMAN,tr|H3BQH3|H3BQH3_HUMAN,tr|Q9UF94|Q9UF94_HUMAN" 3 1513.7917 0.44 36119 21269 3 1513.793645 505.6045 Kelch domain-containing protein 4 OS=Homo sapiens OX=9606 GN=KLHDC4 PE=1 SV=1 6.75 3434.4 - 893112 - - - 1.2961 - 3.036 0.613 - 554.1 1 2 0 0.002 13 0 0 0 1.56E+06 3.55E+06 - - - 8.3848 1 221125_WJC_METTL3_EV_vs_WT_F03.21272.21272.2 2.26E-05 15/32 K.NPGYPQSEGLLGEC[160.03]MIR.H "sp|Q99961|SH3G1_HUMAN,tr|M0R0I3|M0R0I3_HUMAN,tr|M0QYE0|M0QYE0_HUMAN" 3 1919.887 1 36122 21272 2 1919.886133 960.9508 Endophilin-A2 OS=Homo sapiens OX=9606 GN=SH3GL1 PE=1 SV=1 4.53 3434.8 - 740667 - - - -0.4349 - 2.841 0.611 - 451.7 1 2 0 -0.0008 17 0 0 0 6.49E+06 6.51E+06 - - - 6.1207 0.9985 221125_WJC_METTL3_EV_vs_WT_F03.21273.21273.3 0.00681 Nov-40 K.VFEHFLENLDK[136.11].S "sp|P49642|PRI1_HUMAN,tr|A0A5F9ZHB6|A0A5F9ZHB6_HUMAN,tr|A0A3B3ITS8|A0A3B3ITS8_HUMAN" 3 1397.7071 0.08 36123 21273 3 1397.707213 466.9096 DNA primase small subunit OS=Homo sapiens OX=9606 GN=PRIM1 PE=1 SV=1 4.65 3434.9 - 621933 - - - 0.1052 - 2.134 0.209 - 113.8 1 2 0 0.0001 11 0 0 0 9.90E+05 1.19E+07 - - - 3.0234 0.9983 221125_WJC_METTL3_EV_vs_WT_F03.21276.21276.3 0.00707 Nov-44 K.YFSLPFC[160.03]VGSKK.S "sp|Q9HD45|TM9S3_HUMAN,tr|Q5TB53|Q5TB53_HUMAN" 2 1431.7221 0.66 36125 21276 3 1431.718435 478.248 Transmembrane 9 superfamily member 3 OS=Homo sapiens OX=9606 GN=TM9SF3 PE=1 SV=2 9.2 3435.2 - 710194 - - - -2.5305 - 1.832 0.306 - 117.5 1 2 0 -0.0036 12 0 0 0 2.06E+06 3.13E+06 - - - 3.6287 1 221125_WJC_METTL3_EV_vs_WT_F03.21277.21277.3 7.47E-08 17/56 R.GFGFVTFDDHDPVDK.L "sp|P22626|ROA2_HUMAN,tr|A0A7I2V4N0|A0A7I2V4N0_HUMAN,tr|A0A024RA28|A0A024RA28_HUMAN,tr|A0A7I2V4N1|A0A7I2V4N1_HUMAN,tr|A0A7I2V4I6|A0A7I2V4I6_HUMAN,tr|A0A087WUI2|A0A087WUI2_HUMAN,tr|A0A7I2V4S4|A0A7I2V4S4_HUMAN,tr|A0A7I2V323|A0A7I2V323_HUMAN,tr|A0A7I2V3P1|A0A7I2V3P1_HUMAN,tr|A0A7I2V3P7|A0A7I2V3P7_HUMAN" 10 1694.7577 1.45 36126 21277 3 1694.758729 565.9265 Heterogeneous nuclear ribonucleoproteins A2\B1 OS=Homo sapiens OX=9606 GN=HNRNPA2B1 PE=1 SV=2 4.13 3435.3 - 5.69E+06 - - - 0.6361 - 2.429 0.633 - 208 1 2 0 0.0011 15 0 0 0 1.89E+09 1.30E+09 - - - 7.9128 1 221125_WJC_METTL3_EV_vs_WT_F03.21278.21278.2 1.18E-06 22-Dec R.DQDELNPYAAWR.L "sp|O43615|TIM44_HUMAN,tr|M0QXM9|M0QXM9_HUMAN" 2 1476.6634 1.15 36127 21278 2 1476.661438 739.339 Mitochondrial import inner membrane translocase subunit TIM44 OS=Homo sapiens OX=9606 GN=TIMM44 PE=1 SV=2 4.03 3435.3 - 4.29E+06 - - - -1.2996 - 2.776 0.618 - 565.6 1 2 0 -0.0019 12 0 0 0 2.41E+07 2.09E+07 - - - 6.2914 1 221125_WJC_METTL3_EV_vs_WT_F03.21281.21281.3 1.62E-06 17/52 K.FLPLFGHIGGTQSK.G sp|Q5VT06|CE350_HUMAN 1 1500.8089 2.52 36130 21281 3 1500.808934 501.2769 Centrosome-associated protein 350 OS=Homo sapiens OX=9606 GN=CEP350 PE=1 SV=1 8.76 3435.5 - 2.37E+06 - - - 0.0233 - 2.869 0.578 - 307.4 1 2 0 0 14 0 0 0 3.18E+07 1.26E+07 - - - 7.7851 0.9999 221125_WJC_METTL3_EV_vs_WT_F03.21282.21282.3 6.84E-07 14/56 K.QLLADFSC[160.03]NKFPAIK.A "sp|Q08188|TGM3_HUMAN,tr|A0A494C0J7|A0A494C0J7_HUMAN" 2 1750.9076 5.9 36131 21282 3 1750.907907 584.6432 Protein-glutamine gamma-glutamyltransferase E OS=Homo sapiens OX=9606 GN=TGM3 PE=1 SV=4 8.2 3435.5 - 2.26E+06 - - - 0.1599 - 2.945 0.507 - 325.1 1 2 1 0.0003 15 0 0 0 1.27E+07 2.15E+06 - - - 7.0109 1 221125_WJC_METTL3_EV_vs_WT_F03.21284.21284.3 1.99E-05 14/52 K.FLPLFGHIGGTQSK[136.11].G sp|Q5VT06|CE350_HUMAN 1 1508.8231 2.25 36133 21284 3 1508.823116 503.9483 Centrosome-associated protein 350 OS=Homo sapiens OX=9606 GN=CEP350 PE=1 SV=1 8.76 3435.7 - 1.57E+06 - - - 0.0113 - 2.623 0.45 - 169.2 1 2 0 0 14 0 0 0 2.84E+07 1.26E+07 - - - 6.1198 0.9998 221125_WJC_METTL3_EV_vs_WT_F03.21285.21285.2 9.11E-06 13/26 K.NVGLDIEAEVPAVK[136.11].D "sp|P50990|TCPQ_HUMAN,tr|H7C2U0|H7C2U0_HUMAN" 2 1460.7966 0.001 36134 21285 2 1460.799171 731.4056 T-complex protein 1 subunit theta OS=Homo sapiens OX=9606 GN=CCT8 PE=1 SV=4 4.14 3435.8 - 1.37E+06 - - - 1.7532 - 2.386 0.531 - 382.2 1 2 0 0.0026 14 0 0 0 0.00E+00 6.24E+06 - - - 5.1444 0.9833 221125_WJC_METTL3_EV_vs_WT_F03.21286.21286.3 1.26E-08 16/72 R.PSPAISVSVSAPAFYAPQK.K "sp|Q15942|ZYX_HUMAN,tr|H0Y2Y8|H0Y2Y8_HUMAN,tr|C9IZ41|C9IZ41_HUMAN" 3 1916.0044 1.43 36135 21286 3 1916.011412 639.6754 Zyxin OS=Homo sapiens OX=9606 GN=ZYX PE=1 SV=1 9.01 3435.9 - 1.31E+06 - - - 3.6785 - 2.962 0.494 - 290.9 1 1 0 0.007 19 0 0 0 8.11E+06 5.67E+06 - - - 6.7134 1 221125_WJC_METTL3_EV_vs_WT_F03.21287.21287.2 2.33E-09 16/30 K.YGPIADVSIVYDQQSR[166.11].R sp|P62995|TRA2B_HUMAN 1 1819.898 1.96 36136 21287 2 1819.898655 910.9563 Transformer-2 protein homolog beta OS=Homo sapiens OX=9606 GN=TRA2B PE=1 SV=1 4.21 3436 - 2.54E+06 - - - 0.361 - 2.771 0.58 - 779.7 1 2 0 0.0007 16 0 0 0 2.88E+08 1.47E+08 - - - 5.8304 0.9999 221125_WJC_METTL3_EV_vs_WT_F03.21290.21290.3 4.76E-06 13/60 R.ELYHVISFDGSYVNYR.H "sp|P24928|RPB1_HUMAN,tr|A0A6Q8PGB0|A0A6Q8PGB0_HUMAN" 2 1960.9319 1.48 36139 21290 3 1960.929443 654.6513 DNA-directed RNA polymerase II subunit RPB1 OS=Homo sapiens OX=9606 GN=POLR2A PE=1 SV=2 5.32 3436.4 - 916474 - - - -1.2667 - 2.446 0.442 - 199.8 1 2 0 -0.0025 16 0 0 0 5.40E+06 3.65E+06 - - - 5.7622 1 221125_WJC_METTL3_EV_vs_WT_F03.21291.21291.3 6.40E-05 Dec-44 R.SLLQAVSELEKK.H "sp|Q5TA31|RN187_HUMAN,tr|A0A1X7SBW3|A0A1X7SBW3_HUMAN" 2 1343.766 2.75 36140 21291 3 1343.766161 448.9293 E3 ubiquitin-protein ligase RNF187 OS=Homo sapiens OX=9606 GN=RNF187 PE=1 SV=2 5.86 3436.5 - 904351 - - - 0.0967 - 2.237 0.47 - 119 1 2 0 0.0001 12 0 0 0 4.70E+06 1.71E+06 - - - 6.0117 0.9993 221125_WJC_METTL3_EV_vs_WT_F03.21294.21294.3 0.000108 14/68 R.LNR[166.11]LPAAGVGDMVMATVK[136.11].K "sp|P62829|RL23_HUMAN,tr|J3KT29|J3KT29_HUMAN,tr|B9ZVP7|B9ZVP7_HUMAN,tr|C9JD32|C9JD32_HUMAN" 4 1860.008 0.85 36143 21294 3 1860.002019 621.01 60S ribosomal protein L23 OS=Homo sapiens OX=9606 GN=RPL23 PE=1 SV=1 8.75 3436.9 - 689486 - - - -3.2317 - 3.109 0.442 - 171.7 1 2 1 -0.006 18 0 0 0 2.41E+08 2.82E+08 - - - 6.2907 1 221125_WJC_METTL3_EV_vs_WT_F03.21296.21296.4 9.74E-08 18/78 K.LIQQQLVLLLHAHK.C "sp|Q92793|CBP_HUMAN,sp|Q09472|EP300_HUMAN,tr|A0A669KB12|A0A669KB12_HUMAN" 3 1653.009 0.85 36144 21296 4 1653.005685 414.2595 CREB-binding protein OS=Homo sapiens OX=9606 GN=CREBBP PE=1 SV=3 8.76 3437.1 - 795111 - - - -2.003 - 3.296 0.561 - 368.5 1 2 0 -0.0033 14 0 0 0 2.82E+06 3.33E+06 - - - 4.5421 1 221125_WJC_METTL3_EV_vs_WT_F03.21298.21298.3 9.05 19/56 R.GFGFVTFDDHDPVDK[136.11].L "sp|P22626|ROA2_HUMAN,tr|A0A7I2V4N0|A0A7I2V4N0_HUMAN,tr|A0A024RA28|A0A024RA28_HUMAN,tr|A0A7I2V4N1|A0A7I2V4N1_HUMAN,tr|A0A7I2V4I6|A0A7I2V4I6_HUMAN,tr|A0A087WUI2|A0A087WUI2_HUMAN,tr|A0A7I2V4S4|A0A7I2V4S4_HUMAN,tr|A0A7I2V323|A0A7I2V323_HUMAN,tr|A0A7I2V3P1|A0A7I2V3P1_HUMAN,tr|A0A7I2V3P7|A0A7I2V3P7_HUMAN" 10 1702.7719 1.45 36146 21298 3 1702.771484 568.5979 Heterogeneous nuclear ribonucleoproteins A2\B1 OS=Homo sapiens OX=9606 GN=HNRNPA2B1 PE=1 SV=2 4.13 3437.3 - 2.24E+07 - - - -0.2155 - 2.9 0.504 - 347.1 1 2 0 -0.0004 15 0 0 0 1.89E+09 1.30E+09 - - - 6.9372 1 221125_WJC_METTL3_EV_vs_WT_F03.21299.21299.3 1.68E-07 20/72 K.ISK[136.11]PAPYWEGTAVIDGEFK[136.11].E "sp|Q13162|PRDX4_HUMAN,tr|A6NG45|A6NG45_HUMAN" 2 2123.091 0.53 36147 21299 3 2123.092089 708.7043 Peroxiredoxin-4 OS=Homo sapiens OX=9606 GN=PRDX4 PE=1 SV=1 4.68 3437.4 - 4.70E+06 - - - 0.5096 - 3.781 0.608 - 443.6 1 2 0 0.0011 19 0 0 0 1.92E+07 3.63E+07 - - - 8.5858 1 221125_WJC_METTL3_EV_vs_WT_F03.21301.21301.2 2.89E-10 17/30 K.YGPIADVSIVYDQQSR.R sp|P62995|TRA2B_HUMAN 1 1809.8897 1.96 36149 21301 2 1809.889562 905.9521 Transformer-2 protein homolog beta OS=Homo sapiens OX=9606 GN=TRA2B PE=1 SV=1 4.21 3437.4 - 3.26E+06 - - - -0.0917 - 2.875 0.679 - 888.7 1 2 0 -0.0002 16 0 0 0 2.88E+08 1.47E+08 - - - 6.6524 0.9999 221125_WJC_METTL3_EV_vs_WT_F03.21302.21302.3 0.000455 Dec-60 K.YGPIADVSIVYDQQSR.R sp|P62995|TRA2B_HUMAN 1 1809.8897 1.8 36150 21302 3 1809.890888 604.3039 Transformer-2 protein homolog beta OS=Homo sapiens OX=9606 GN=TRA2B PE=1 SV=1 4.21 3437.5 - 2.36E+06 - - - 0.6409 - 2.139 0.445 - 170.4 1 2 0 0.0012 16 0 0 0 1.18E+08 6.53E+07 - - - 5.4519 1 221125_WJC_METTL3_EV_vs_WT_F03.21304.21304.3 3.31E-06 15/44 R.EASIDILHSIVK[136.11].R "sp|O00231|PSD11_HUMAN,tr|J3QRY4|J3QRY4_HUMAN" 2 1331.754 0.68 36152 21304 3 1331.753878 444.9253 26S proteasome non-ATPase regulatory subunit 11 OS=Homo sapiens OX=9606 GN=PSMD11 PE=1 SV=3 5.32 3437.6 - 1.85E+06 - - - -0.1044 - 2.502 0.44 - 334.1 1 2 0 -0.0001 12 0 0 0 2.94E+07 4.35E+07 - - - 5.9876 0.9998 221125_WJC_METTL3_EV_vs_WT_F03.21305.21305.2 4.04E-10 16/28 R.GFGFVTFDDHDPVDK[136.11].L "sp|P22626|ROA2_HUMAN,tr|A0A7I2V4N0|A0A7I2V4N0_HUMAN,tr|A0A024RA28|A0A024RA28_HUMAN,tr|A0A7I2V4N1|A0A7I2V4N1_HUMAN,tr|A0A7I2V4I6|A0A7I2V4I6_HUMAN,tr|A0A087WUI2|A0A087WUI2_HUMAN,tr|A0A7I2V4S4|A0A7I2V4S4_HUMAN,tr|A0A7I2V323|A0A7I2V323_HUMAN,tr|A0A7I2V3P1|A0A7I2V3P1_HUMAN,tr|A0A7I2V3P7|A0A7I2V3P7_HUMAN" 10 1702.7719 1.46 36153 21305 2 1702.768924 852.3932 Heterogeneous nuclear ribonucleoproteins A2\B1 OS=Homo sapiens OX=9606 GN=HNRNPA2B1 PE=1 SV=2 4.13 3437.8 - 1.66E+06 - - - -1.719 - 2.932 0.488 - 902 1 2 0 -0.0029 15 0 0 0 2.66E+08 1.82E+08 - - - 5.2891 0.9999 221125_WJC_METTL3_EV_vs_WT_F03.21306.21306.2 6.55E-11 17/24 K.QTADFLQEYVTNK[136.11].T "sp|Q9ULX6|AKP8L_HUMAN,tr|A0A7P0TAJ5|A0A7P0TAJ5_HUMAN,tr|A0A7P0TAE3|A0A7P0TAE3_HUMAN" 3 1563.766 0.55 36154 21306 2 1563.768234 782.8903 A-kinase anchor protein 8-like OS=Homo sapiens OX=9606 GN=AKAP8L PE=1 SV=4 4.37 3437.9 - 1.65E+06 - - - 1.4043 - 3.276 0.487 - 1217.3 1 2 0 0.0022 13 0 0 0 2.32E+07 4.24E+07 - - - 5.6828 0.9999 221125_WJC_METTL3_EV_vs_WT_F03.21308.21308.3 5.27E-08 18/56 K.NADVRPPFTYASLIR.Q "sp|Q8IVH2|FOXP4_HUMAN,tr|B7ZBM3|B7ZBM3_HUMAN" 2 1718.9104 2.7 36156 21308 3 1718.91728 573.9774 Forkhead box protein P4 OS=Homo sapiens OX=9606 GN=FOXP4 PE=1 SV=1 8.75 3438.1 - 1.21E+06 - - - 4.0002 - 3.292 0.559 - 456.5 1 2 0 0.0069 15 0 0 0 1.99E+07 7.37E+06 - - - 7.8794 0.9999 221125_WJC_METTL3_EV_vs_WT_F03.21309.21309.3 0.00339 15/44 R.EASIDILHSIVK.R "sp|O00231|PSD11_HUMAN,tr|J3QRY4|J3QRY4_HUMAN" 2 1323.7398 0.67 36157 21309 3 1323.739136 442.2539 26S proteasome non-ATPase regulatory subunit 11 OS=Homo sapiens OX=9606 GN=PSMD11 PE=1 SV=3 5.32 3438.2 - 1.16E+06 - - - -0.5145 - 2.584 0.39 - 290.4 1 2 0 -0.0007 12 0 0 0 2.94E+07 4.36E+07 - - - 5.5194 0.9998 221125_WJC_METTL3_EV_vs_WT_F03.21311.21311.3 3.50E-05 13/64 K.NPGYPQSEGLLGEC[160.03]MIR.H "sp|Q99961|SH3G1_HUMAN,tr|M0R0I3|M0R0I3_HUMAN,tr|M0QYE0|M0QYE0_HUMAN" 3 1919.887 0.32 36159 21311 3 1919.890627 640.9696 Endophilin-A2 OS=Homo sapiens OX=9606 GN=SH3GL1 PE=1 SV=1 4.53 3438.5 - 858909 - - - 1.9058 - 2.576 0.394 - 191.5 1 2 0 0.0037 17 0 0 0 5.74E+06 1.82E+07 - - - 5.3222 1 221125_WJC_METTL3_EV_vs_WT_F03.21312.21312.3 6.35E-07 16/68 K.EPNPPIDEVISTPGVVAR.F "sp|P52294|IMA5_HUMAN,tr|C9JWD9|C9JWD9_HUMAN,tr|C9JYI4|C9JYI4_HUMAN,tr|C9J352|C9J352_HUMAN,tr|C9J4U1|C9J4U1_HUMAN,tr|F2Z3G4|F2Z3G4_HUMAN" 6 1888.9894 0.87 36160 21312 3 1888.98794 630.6704 Importin subunit alpha-5 OS=Homo sapiens OX=9606 GN=KPNA1 PE=1 SV=3 4.14 3438.6 - 847419 - - - -0.7951 - 3.254 0.47 - 317.5 1 2 0 -0.0015 18 0 0 0 1.57E+07 1.80E+07 - - - 6.7177 0.7983 221125_WJC_METTL3_EV_vs_WT_F03.21315.21315.3 7.89 Jul-44 R.DQDELNPYAAWR.L "sp|O43615|TIM44_HUMAN,tr|M0QXM9|M0QXM9_HUMAN" 2 1476.6634 4.71 36163 21315 3 1476.66639 493.2284 Mitochondrial import inner membrane translocase subunit TIM44 OS=Homo sapiens OX=9606 GN=TIMM44 PE=1 SV=2 4.03 3439 - 305661 - - - 2.054 - 1.17 0.126 - 55.7 1 2 0 0.003 12 0 0 0 2.74E+06 5.82E+05 - - - 0.3791 0.9998 221125_WJC_METTL3_EV_vs_WT_F03.21318.21318.3 0.000578 Oct-40 R.EHLEMLIDQLK.L sp|Q8IWJ2|GCC2_HUMAN 1 1367.7119 -1 36165 21318 3 1367.710357 456.9112 GRIP and coiled-coil domain-containing protein 2 OS=Homo sapiens OX=9606 GN=GCC2 PE=1 SV=4 4.65 3439.4 - 753641 - - - -1.1187 - 2.07 0.347 - 118.4 1 2 0 -0.0015 11 0 0 0 0.00E+00 0.00E+00 - - - 4.4751 0.9998 221125_WJC_METTL3_EV_vs_WT_F03.21322.21322.2 1.45E-08 15/24 K.QTADFLQEYVTNK.T "sp|Q9ULX6|AKP8L_HUMAN,tr|A0A7P0TAJ5|A0A7P0TAJ5_HUMAN,tr|A0A7P0TAE3|A0A7P0TAE3_HUMAN" 3 1555.7518 0.58 36169 21322 2 1555.749186 778.8832 A-kinase anchor protein 8-like OS=Homo sapiens OX=9606 GN=AKAP8L PE=1 SV=4 4.37 3439.6 - 2.60E+06 - - - -1.7046 - 2.67 0.48 - 609.6 1 2 0 -0.0027 13 0 0 0 2.32E+07 4.00E+07 - - - 5.106 1 221125_WJC_METTL3_EV_vs_WT_F03.21324.21324.2 6.90E-10 17/24 F.GFVTFDDHDPVDK[136.11].L "sp|P22626|ROA2_HUMAN,tr|A0A7I2V4N0|A0A7I2V4N0_HUMAN,tr|A0A024RA28|A0A024RA28_HUMAN,tr|A0A7I2V4N1|A0A7I2V4N1_HUMAN,tr|A0A7I2V4I6|A0A7I2V4I6_HUMAN,tr|A0A087WUI2|A0A087WUI2_HUMAN,tr|A0A7I2V4S4|A0A7I2V4S4_HUMAN,tr|A0A7I2V323|A0A7I2V323_HUMAN,tr|A0A7I2V3P1|A0A7I2V3P1_HUMAN,tr|A0A7I2V3P7|A0A7I2V3P7_HUMAN" 10 1498.682 1.72 36171 21324 2 1498.680613 750.3483 Heterogeneous nuclear ribonucleoproteins A2\B1 OS=Homo sapiens OX=9606 GN=HNRNPA2B1 PE=1 SV=2 4.13 3439.9 - 1.11E+06 - - - -0.9081 - 3.227 0.597 - 1028.5 1 1 0 -0.0014 13 0 0 0 4.50E+07 2.62E+07 - - - 6.4568 0.9999 221125_WJC_METTL3_EV_vs_WT_F03.21326.21326.2 3.54E-08 28-Dec R.QNVGTLESFSPGDFR.T sp|Q6ULP2|AFTIN_HUMAN 1 1652.7794 3.44 36173 21326 2 1652.777356 827.397 Aftiphilin OS=Homo sapiens OX=9606 GN=AFTPH PE=1 SV=3 4.37 3440.1 - 793134 - - - -1.267 - 2.565 0.574 - 379.3 1 2 0 -0.0021 15 0 0 0 3.75E+07 1.09E+07 - - - 5.5958 0.9998 221125_WJC_METTL3_EV_vs_WT_F03.21328.21328.3 0.00209 13/52 K.NVGLDIEAEVPAVK[136.11].D "sp|P50990|TCPQ_HUMAN,tr|H7C2U0|H7C2U0_HUMAN" 2 1460.7966 0.04 36175 21328 3 1460.796563 487.9395 T-complex protein 1 subunit theta OS=Homo sapiens OX=9606 GN=CCT8 PE=1 SV=4 4.14 3440.4 - 402154 - - - -0.0322 - 2.113 0.359 - 175.3 1 2 0 0 14 0 0 0 2.96E+05 7.05E+06 - - - 4.5306 0.9998 221125_WJC_METTL3_EV_vs_WT_F03.21333.21333.2 0.000819 20-Dec R.SYNDELQFLEK[136.11].L sp|Q9Y3I0|RTCB_HUMAN 1 1392.6653 1.47 36178 21333 2 1392.662625 697.3399 RNA-splicing ligase RtcB homolog OS=Homo sapiens OX=9606 GN=RTCB PE=1 SV=1 4.14 3440.9 - 1.28E+07 - - - -1.8928 - 2.405 0.526 - 315.8 1 2 0 -0.0026 11 0 0 0 2.02E+08 1.38E+08 - - - 5.2992 1 221125_WJC_METTL3_EV_vs_WT_F03.21335.21335.3 4.62E-05 Dec-52 R.FTQAGSEVSALLGR.L "sp|P06576|ATPB_HUMAN,tr|F8W0P7|F8W0P7_HUMAN,tr|H0YH81|H0YH81_HUMAN" 3 1434.7467 2.2 36180 21335 3 1434.744947 479.2562 "ATP synthase subunit beta, mitochondrial OS=Homo sapiens OX=9606 GN=ATP5F1B PE=1 SV=3" 6 3441 - 4.97E+06 - - - -1.2169 - 2.388 0.508 - 177.1 1 2 0 -0.0017 14 0 0 0 8.87E+07 4.04E+07 - - - 6.5165 1 221125_WJC_METTL3_EV_vs_WT_F03.21337.21337.2 1.80E-09 16/24 F.GFVTFDDHDPVDK.L "sp|P22626|ROA2_HUMAN,tr|A0A7I2V4N0|A0A7I2V4N0_HUMAN,tr|A0A024RA28|A0A024RA28_HUMAN,tr|A0A7I2V4N1|A0A7I2V4N1_HUMAN,tr|A0A7I2V4I6|A0A7I2V4I6_HUMAN,tr|A0A087WUI2|A0A087WUI2_HUMAN,tr|A0A7I2V4S4|A0A7I2V4S4_HUMAN,tr|A0A7I2V323|A0A7I2V323_HUMAN,tr|A0A7I2V3P1|A0A7I2V3P1_HUMAN,tr|A0A7I2V3P7|A0A7I2V3P7_HUMAN" 10 1490.6678 1.71 36182 21337 2 1490.66628 746.3412 Heterogeneous nuclear ribonucleoproteins A2\B1 OS=Homo sapiens OX=9606 GN=HNRNPA2B1 PE=1 SV=2 4.13 3441.1 - 3.50E+06 - - - -1.0022 - 3.211 0.67 - 990.7 1 1 0 -0.0015 13 0 0 0 4.40E+07 2.58E+07 - - - 6.9832 0.9999 221125_WJC_METTL3_EV_vs_WT_F03.21340.21340.3 1.42E-05 14/52 R.FTQAGSEVSALLGR[166.11].L "sp|P06576|ATPB_HUMAN,tr|F8W0P7|F8W0P7_HUMAN,tr|H0YH81|H0YH81_HUMAN" 3 1444.755 2.2 36185 21340 3 1444.752748 482.5923 "ATP synthase subunit beta, mitochondrial OS=Homo sapiens OX=9606 GN=ATP5F1B PE=1 SV=3" 6 3441.4 - 2.01E+06 - - - -1.5331 - 2.329 0.475 - 309.4 1 2 0 -0.0022 14 0 0 0 8.87E+07 4.04E+07 - - - 6.0819 1 221125_WJC_METTL3_EV_vs_WT_F03.21341.21341.2 1.59E-08 15/32 R.VQLDTIQGELNAPTQFK.G sp|Q7Z3B4|NUP54_HUMAN 1 1900.9894 2.71 36186 21341 2 1900.987906 951.502 Nucleoporin p54 OS=Homo sapiens OX=9606 GN=NUP54 PE=1 SV=2 4.37 3441.6 - 1.70E+06 - - - -0.808 - 3.47 0.601 - 496.1 1 2 0 -0.0015 17 0 0 0 2.18E+08 8.05E+07 - - - 6.5383 1 221125_WJC_METTL3_EV_vs_WT_F03.21343.21343.2 1.74E-07 15/32 R.VQLDTIQGELNAPTQFK[136.11].G sp|Q7Z3B4|NUP54_HUMAN 1 1909.0036 2.71 36188 21343 2 1908.999478 955.5091 Nucleoporin p54 OS=Homo sapiens OX=9606 GN=NUP54 PE=1 SV=2 4.37 3441.8 - 1.28E+06 - - - -2.1812 - 3.208 0.564 - 476.5 1 2 0 -0.0042 17 0 0 0 2.18E+08 8.05E+07 - - - 6.0712 1 221125_WJC_METTL3_EV_vs_WT_F03.21347.21347.2 2.37E-08 26-Dec R.FTQAGSEVSALLGR.L "sp|P06576|ATPB_HUMAN,tr|F8W0P7|F8W0P7_HUMAN,tr|H0YH81|H0YH81_HUMAN" 3 1434.7467 1.96 36190 21347 2 1434.743654 718.3806 "ATP synthase subunit beta, mitochondrial OS=Homo sapiens OX=9606 GN=ATP5F1B PE=1 SV=3" 6 3442.3 - 2.04E+07 - - - -2.1181 - 2.767 0.66 - 419.5 1 2 0 -0.003 14 0 0 0 3.95E+08 2.02E+08 - - - 6.4688 0.9998 221125_WJC_METTL3_EV_vs_WT_F03.21348.21348.3 3.22E-10 22/80 K.LVEQLDIEETEQSKLPQYLER.F "sp|Q92552|RT27_HUMAN,tr|G5EA06|G5EA06_HUMAN,tr|D6RH20|D6RH20_HUMAN" 3 2559.3068 1.12 36191 21348 3 2559.299389 854.1095 "28S ribosomal protein S27, mitochondrial OS=Homo sapiens OX=9606 GN=MRPS27 PE=1 SV=3" 4.14 3442.4 - 3.96E+06 - - - -2.9012 - 3.846 0.531 - 402.7 1 2 1 -0.0074 21 0 0 0 6.03E+07 5.41E+07 - - - 7.6875 0.9026 221125_WJC_METTL3_EV_vs_WT_F03.21353.21353.2 6.39 12-Jul K.DFDWNLK.H "sp|Q9Y5A9|YTHD2_HUMAN,sp|Q7Z739|YTHD3_HUMAN,sp|Q5VYJ5|MALR1_HUMAN,tr|A0A087X0Q1|A0A087X0Q1_HUMAN,tr|A0A024R7W5|A0A024R7W5_HUMAN,tr|U5GXS0|U5GXS0_HUMAN,tr|A0A087WY31|A0A087WY31_HUMAN" 7 936.4341 1.22 36196 21353 2 936.431289 469.2243 YTH domain-containing family protein 2 OS=Homo sapiens OX=9606 GN=YTHDF2 PE=1 SV=2 4.21 3442.9 - 1.85E+06 - - - -3.036 - 1.167 0.073 - 169.7 1 2 0 -0.0028 7 0 0 0 3.16E+07 2.58E+07 - - - 0.0686 1 221125_WJC_METTL3_EV_vs_WT_F03.21357.21357.3 3.03E-05 21/64 R.VQLDTIQGELNAPTQFK[136.11].G sp|Q7Z3B4|NUP54_HUMAN 1 1909.0036 2.45 36198 21357 3 1908.99918 637.3418 Nucleoporin p54 OS=Homo sapiens OX=9606 GN=NUP54 PE=1 SV=2 4.37 3443.4 - 5.05E+06 - - - -2.3373 - 3.834 0.575 - 542.2 1 2 0 -0.0045 17 0 0 0 1.72E+08 7.03E+07 - - - 8.3446 1 221125_WJC_METTL3_EV_vs_WT_F03.21360.21360.2 7.96E-09 15/26 K.NVGLDIEAEVPAVK.D "sp|P50990|TCPQ_HUMAN,tr|H7C2U0|H7C2U0_HUMAN" 2 1452.7824 0.36 36201 21360 2 1452.777899 727.3985 T-complex protein 1 subunit theta OS=Homo sapiens OX=9606 GN=CCT8 PE=1 SV=4 4.14 3443.7 - 2.03E+06 - - - -3.1051 - 2.533 0.635 - 561.3 1 2 0 -0.0045 14 0 0 0 5.22E+07 1.44E+08 - - - 6.062 1 221125_WJC_METTL3_EV_vs_WT_F03.21361.21361.2 1.56E-05 17/34 R.SLVEASSSGVSVLSLC[160.03]EK[136.11].G "sp|Q9UQ80|PA2G4_HUMAN,tr|F8W0A3|F8W0A3_HUMAN,tr|F8VR77|F8VR77_HUMAN,tr|H0YIN7|H0YIN7_HUMAN" 4 1858.9437 0.14 36202 21361 2 1858.933779 930.4791 Proliferation-associated protein 2G4 OS=Homo sapiens OX=9606 GN=PA2G4 PE=1 SV=3 4.53 3443.8 - 1.90E+06 - - - -5.3611 - 3.443 0.527 - 727.7 1 2 0 -0.01 18 0 0 0 3.39E+06 2.41E+07 - - - 5.9699 1 221125_WJC_METTL3_EV_vs_WT_F03.21365.21365.2 9.06E-12 15/26 R.FTQAGSEVSALLGR[166.11].L "sp|P06576|ATPB_HUMAN,tr|F8W0P7|F8W0P7_HUMAN,tr|H0YH81|H0YH81_HUMAN" 3 1444.755 1.96 36204 21365 2 1444.751348 723.3848 "ATP synthase subunit beta, mitochondrial OS=Homo sapiens OX=9606 GN=ATP5F1B PE=1 SV=3" 6 3444.3 - 1.31E+07 - - - -2.5022 - 3.133 0.684 - 916.3 1 2 0 -0.0036 14 0 0 0 3.95E+08 2.02E+08 - - - 6.9577 1 221125_WJC_METTL3_EV_vs_WT_F03.21371.21371.2 3.23E-08 16/28 K.TLNEWSSQINPDLVR.E sp|P48507|GSH0_HUMAN 1 1770.8901 5.23 36209 21371 2 1770.889155 886.4523 Glutamate--cysteine ligase regulatory subunit OS=Homo sapiens OX=9606 GN=GCLM PE=1 SV=1 4.37 3444.9 - 2.32E+06 - - - -0.5127 - 3.118 0.609 - 819.8 1 2 0 -0.0009 15 0 0 0 3.22E+07 6.16E+06 - - - 6.3346 0.9811 221125_WJC_METTL3_EV_vs_WT_F03.21375.21375.2 0.00065 28-Dec R.QNVGTLESFSPGDFR[166.11].T sp|Q6ULP2|AFTIN_HUMAN 1 1662.7877 3.42 36212 21375 2 1662.800004 832.4011 Aftiphilin OS=Homo sapiens OX=9606 GN=AFTPH PE=1 SV=3 4.37 3445.4 - 3.78E+06 - - - 7.3876 - 1.925 0.442 - 287.9 1 2 0 0.0123 15 0 0 0 3.72E+07 1.09E+07 - - - 3.9119 1 221125_WJC_METTL3_EV_vs_WT_F03.21377.21377.4 3.47E-06 24/96 K.LSSLIILMPHHVEPLER.L "sp|P50454|SERPH_HUMAN,tr|E9PKH2|E9PKH2_HUMAN,tr|E9PPV6|E9PPV6_HUMAN,tr|E9PR70|E9PR70_HUMAN,tr|E9PJH8|E9PJH8_HUMAN" 5 1983.0976 1.89 36214 21377 4 1983.092064 496.7817 Serpin H1 OS=Homo sapiens OX=9606 GN=SERPINH1 PE=1 SV=2 6 3445.6 - 2.18E+06 - - - -2.7679 - 4.304 0.582 - 651.4 1 2 0 -0.0055 17 0 0 0 6.75E+07 3.57E+07 - - - 4.797 0.9924 221125_WJC_METTL3_EV_vs_WT_F03.21380.21380.2 3.07E-10 17/34 S.SIAAFSPSPGFSPYNVSK.T "sp|Q6PKH6|DR4L2_HUMAN,sp|Q9BTZ2|DHRS4_HUMAN,tr|A0A087WSZ6|A0A087WSZ6_HUMAN,tr|A0A087WXI8|A0A087WXI8_HUMAN,tr|H0YKN3|H0YKN3_HUMAN" 5 1854.9152 1.84 36216 21380 2 1854.912447 928.4649 Dehydrogenase\reductase SDR family member 4-like 2 OS=Homo sapiens OX=9606 GN=DHRS4L2 PE=2 SV=2 8.31 3446 - 3.86E+06 - - - -1.4923 - 3.004 0.535 - 796.6 1 1 0 -0.0028 18 0 0 0 3.93E+07 2.13E+07 - - - 5.6959 1 221125_WJC_METTL3_EV_vs_WT_F03.21382.21382.2 2.92E-08 18/28 R.VVSEDFLQDVSASTK.S "sp|P09874|PARP1_HUMAN,tr|A0A7I2V3E1|A0A7I2V3E1_HUMAN" 2 1623.7992 1.17 36217 21382 2 1623.794969 812.9069 Poly [ADP-ribose] polymerase 1 OS=Homo sapiens OX=9606 GN=PARP1 PE=1 SV=4 4.03 3446.2 - 8.08E+06 - - - -2.5945 - 3.014 0.662 - 930.9 1 2 0 -0.0042 15 0 0 0 6.81E+08 5.83E+08 - - - 6.6416 1 221125_WJC_METTL3_EV_vs_WT_F03.21383.21383.2 2.42E-09 17/28 R.VVSEDFLQDVSASTK[136.11].S "sp|P09874|PARP1_HUMAN,tr|A0A7I2V3E1|A0A7I2V3E1_HUMAN" 2 1631.8134 1.17 36218 21383 2 1631.808071 816.914 Poly [ADP-ribose] polymerase 1 OS=Homo sapiens OX=9606 GN=PARP1 PE=1 SV=4 4.03 3446.3 - 7.87E+06 - - - -3.2547 - 3.032 0.689 - 752.5 1 2 0 -0.0053 15 0 0 0 6.81E+08 5.83E+08 - - - 6.8554 0.9998 221125_WJC_METTL3_EV_vs_WT_F03.21384.21384.2 1.00E-05 18-Nov R.EC[160.03]LNLWGYER[166.11].V sp|Q86U44|MTA70_HUMAN 1 1348.6109 0.01 36219 21384 2 1348.609065 675.3127 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 4.53 3446.3 - 4.00E+06 - - - -1.3911 - 1.974 0.561 - 388.4 1 2 0 -0.0019 10 0 0 0 1.82E+07 1.31E+09 - - - 5.0822 1 221125_WJC_METTL3_EV_vs_WT_F03.21388.21388.3 2.73E-07 18/44 R.DLAHLAAEVEGK.C "sp|Q9HCM9|TRI39_HUMAN,tr|A0A0G2JKY0|A0A0G2JKY0_HUMAN,tr|A0A096LP39|A0A096LP39_HUMAN,tr|A0A140TA46|A0A140TA46_HUMAN,tr|A2AAZ6|A2AAZ6_HUMAN,tr|H0Y735|H0Y735_HUMAN" 6 1251.6459 2.17 36223 21388 3 1251.644073 418.2226 E3 ubiquitin-protein ligase TRIM39 OS=Homo sapiens OX=9606 GN=TRIM39 PE=1 SV=2 4.65 3446.8 - 1.41E+06 - - - -1.4725 - 3.123 0.562 - 472.9 1 2 0 -0.0018 12 0 0 0 2.46E+07 1.14E+07 - - - 7.9618 1 221125_WJC_METTL3_EV_vs_WT_F03.21391.21391.3 6.65E-07 15/64 R.VQLDTIQGELNAPTQFK.G sp|Q7Z3B4|NUP54_HUMAN 1 1900.9894 2.45 36224 21391 3 1900.98516 634.6704 Nucleoporin p54 OS=Homo sapiens OX=9606 GN=NUP54 PE=1 SV=2 4.37 3447.2 - 1.09E+07 - - - -2.2525 - 2.951 0.518 - 245.8 1 2 0 -0.0043 17 0 0 0 1.72E+08 7.03E+07 - - - 7.0478 0.9999 221125_WJC_METTL3_EV_vs_WT_F03.21392.21392.3 3.18E-08 13/40 K.LDPHLVLDQLR.C "sp|P35580|MYH10_HUMAN,sp|P35579|MYH9_HUMAN" 2 1317.7405 0.76 36225 21392 3 1317.736906 440.2541 Myosin-10 OS=Homo sapiens OX=9606 GN=MYH10 PE=1 SV=3 5.21 3447.3 - 2.73E+06 - - - -2.716 - 2.466 0.513 - 276 1 2 0 -0.0036 11 0 0 0 4.08E+07 5.39E+07 - - - 6.8226 1 221125_WJC_METTL3_EV_vs_WT_F03.21394.21394.2 1.12E-10 22/36 R.AALETDENLLLC[160.03]APTGAGK.T "sp|O75643|U520_HUMAN,tr|A0A494C1A5|A0A494C1A5_HUMAN" 2 1942.967 2.43 36227 21394 2 1942.959071 972.4908 U5 small nuclear ribonucleoprotein 200 kDa helicase OS=Homo sapiens OX=9606 GN=SNRNP200 PE=1 SV=2 4.14 3447.5 - 2.40E+06 - - - -4.0773 - 4.433 0.673 - 1181.9 1 2 0 -0.0079 19 0 0 0 6.14E+07 2.53E+07 - - - 7.6703 0.9993 221125_WJC_METTL3_EV_vs_WT_F03.21395.21395.2 0.000294 14/24 K.AEVTLDGVWPTDK.T "sp|P52948|NUP98_HUMAN,tr|A0A3B3ITD8|A0A3B3ITD8_HUMAN" 2 1429.7089 7.63 36228 21395 2 1429.703804 715.8617 Nuclear pore complex protein Nup98-Nup96 OS=Homo sapiens OX=9606 GN=NUP98 PE=1 SV=4 4.03 3447.6 - 1.79E+06 - - - -3.5714 - 2.796 0.46 - 518.4 1 2 0 -0.0051 13 0 0 0 5.97E+07 7.83E+06 - - - 5.0758 0.9999 221125_WJC_METTL3_EV_vs_WT_F03.21400.21400.3 1.80E-06 13/40 K.LDPHLVLDQLR[166.11].C "sp|P35580|MYH10_HUMAN,sp|P35579|MYH9_HUMAN" 2 1327.7488 0.76 36231 21400 3 1327.744662 443.5902 Myosin-10 OS=Homo sapiens OX=9606 GN=MYH10 PE=1 SV=3 5.21 3448.3 - 3.23E+06 - - - -3.0827 - 2.458 0.527 - 286.9 1 2 0 -0.0041 11 0 0 0 4.10E+07 5.39E+07 - - - 6.9693 1 221125_WJC_METTL3_EV_vs_WT_F03.21401.21401.2 2.35E-05 15/26 K.TGEEIFGTIGMRPN.A "sp|Q99873|ANM1_HUMAN,tr|E9PKG1|E9PKG1_HUMAN" 2 1520.7293 2.47 36232 21401 2 1520.724477 761.3719 Protein arginine N-methyltransferase 1 OS=Homo sapiens OX=9606 GN=PRMT1 PE=1 SV=3 4.53 3448.4 - 3.61E+06 - - - -3.1899 - 3.042 0.563 - 706.8 1 1 0 -0.0049 14 0 0 0 9.17E+07 3.72E+07 - - - 5.9896 1 221125_WJC_METTL3_EV_vs_WT_F03.21403.21403.2 1.07E-10 23/36 R.AALETDENLLLC[160.03]APTGAGK[136.11].T "sp|O75643|U520_HUMAN,tr|A0A494C1A5|A0A494C1A5_HUMAN" 2 1950.9812 2.43 36234 21403 2 1950.98145 976.4979 U5 small nuclear ribonucleoprotein 200 kDa helicase OS=Homo sapiens OX=9606 GN=SNRNP200 PE=1 SV=2 4.14 3448.6 - 2.30E+06 - - - 0.1317 - 4.173 0.671 - 1378.7 1 2 0 0.0003 19 0 0 0 6.14E+07 2.53E+07 - - - 7.5093 1 221125_WJC_METTL3_EV_vs_WT_F03.21404.21404.2 1.86E-08 14/34 S.SIAAFSPSPGFSPYNVSK[136.11].T "sp|Q6PKH6|DR4L2_HUMAN,sp|Q9BTZ2|DHRS4_HUMAN,tr|A0A087WSZ6|A0A087WSZ6_HUMAN,tr|A0A087WXI8|A0A087WXI8_HUMAN,tr|H0YKN3|H0YKN3_HUMAN" 5 1862.9294 1.84 36235 21404 2 1862.926002 932.472 Dehydrogenase\reductase SDR family member 4-like 2 OS=Homo sapiens OX=9606 GN=DHRS4L2 PE=2 SV=2 8.31 3448.7 - 1.73E+06 - - - -1.8321 - 2.993 0.565 - 456.8 1 1 0 -0.0034 18 0 0 0 3.93E+07 2.13E+07 - - - 5.9083 1 221125_WJC_METTL3_EV_vs_WT_F03.21408.21408.3 5.22E-08 13/56 R.VVSEDFLQDVSASTK[136.11].S "sp|P09874|PARP1_HUMAN,tr|A0A7I2V3E1|A0A7I2V3E1_HUMAN" 2 1631.8134 1.12 36237 21408 3 1631.816115 544.9451 Poly [ADP-ribose] polymerase 1 OS=Homo sapiens OX=9606 GN=PARP1 PE=1 SV=4 4.03 3449.2 - 6.57E+06 - - - 1.6748 - 2.686 0.584 - 292.6 1 2 0 0.0027 15 0 0 0 1.01E+08 8.96E+07 - - - 7.6285 0.9999 221125_WJC_METTL3_EV_vs_WT_F03.21409.21409.3 1.53E-09 19/72 R.AALETDENLLLC[160.03]APTGAGK.T "sp|O75643|U520_HUMAN,tr|A0A494C1A5|A0A494C1A5_HUMAN" 2 1942.967 2.38 36238 21409 3 1942.961162 648.6629 U5 small nuclear ribonucleoprotein 200 kDa helicase OS=Homo sapiens OX=9606 GN=SNRNP200 PE=1 SV=2 4.14 3449.3 - 4.42E+06 - - - -3.0011 - 3.608 0.534 - 410 1 2 0 -0.0058 19 0 0 0 8.19E+07 3.44E+07 - - - 7.6444 1 221125_WJC_METTL3_EV_vs_WT_F03.21411.21411.2 2.71E-12 16/30 K.WNTDNTLGTEISWENK.L "sp|Q9Y277|VDAC3_HUMAN,tr|E5RHE1|E5RHE1_HUMAN,tr|E5RJN6|E5RJN6_HUMAN,tr|E5RK27|E5RK27_HUMAN,tr|E5RFP6|E5RFP6_HUMAN,tr|E5RHZ6|E5RHZ6_HUMAN" 6 1906.8697 1.64 36240 21411 2 1906.869101 954.4421 Voltage-dependent anion-selective channel protein 3 OS=Homo sapiens OX=9606 GN=VDAC3 PE=1 SV=1 4.14 3449.5 - 2.61E+06 - - - -0.3251 - 3.486 0.721 - 724.3 1 2 0 -0.0006 16 0 0 0 3.13E+07 1.91E+07 - - - 7.4362 0.9996 221125_WJC_METTL3_EV_vs_WT_F03.21412.21412.3 2.40E-07 23/72 R.AALETDENLLLC[160.03]APTGAGK[136.11].T "sp|O75643|U520_HUMAN,tr|A0A494C1A5|A0A494C1A5_HUMAN" 2 1950.9812 2.53 36241 21412 3 1950.969744 651.3343 U5 small nuclear ribonucleoprotein 200 kDa helicase OS=Homo sapiens OX=9606 GN=SNRNP200 PE=1 SV=2 4.14 3449.7 - 2.09E+06 - - - -5.8683 - 4.009 0.503 - 684.2 1 2 0 -0.0114 19 0 0 0 8.73E+07 3.46E+07 - - - 7.5562 0.9498 221125_WJC_METTL3_EV_vs_WT_F03.21413.21413.2 0.00142 28-Oct R.SGGGFSSGSAGIINY.Q sp|P04264|K2C1_HUMAN 1 1372.6259 - 36242 21413 2 1372.627441 687.3202 "Keratin, type II cytoskeletal 1 OS=Homo sapiens OX=9606 GN=KRT1 PE=1 SV=6" 5.24 3449.8 - 2.03E+06 - - - 1.1161 - 1.625 0.347 - 201.5 1 1 0 0.0015 15 0 0 0 - - - - - 2.7971 0.9999 221125_WJC_METTL3_EV_vs_WT_F03.21415.21415.3 6.41E-05 Nov-40 R.WYEWLDPSIK[136.11]K[136.11].T sp|Q99459|CDC5L_HUMAN 1 1479.7733 1.25 36244 21415 3 1479.771576 494.265 Cell division cycle 5-like protein OS=Homo sapiens OX=9606 GN=CDC5L PE=1 SV=2 6.07 3450 - 1.45E+06 - - - -1.1664 - 2.049 0.436 - 200 1 2 0 -0.0017 11 0 0 0 1.46E+07 1.17E+07 - - - 5.4384 0.999 221125_WJC_METTL3_EV_vs_WT_F03.21416.21416.3 0.000134 17/56 K.VVSSVLQFGNISFK[136.11]K[136.11].E sp|P35580|MYH10_HUMAN 1 1667.9581 0.54 36245 21416 3 1667.955747 556.9933 Myosin-10 OS=Homo sapiens OX=9606 GN=MYH10 PE=1 SV=3 10 3450.1 - 930339 - - - -1.4365 - 2.611 0.221 - 279.6 1 2 0 -0.0024 15 0 0 0 9.01E+06 1.67E+07 - - - 3.5076 0.9997 221125_WJC_METTL3_EV_vs_WT_F03.21421.21421.4 2.49E-05 20/132 R.LLQGR[166.11]PPLDFYPPGVHPSGLVPR[166.11].E sp|P48634|PRC2A_HUMAN 1 2531.3916 1.19 36248 21421 4 2531.388157 633.8552 Protein PRRC2A OS=Homo sapiens OX=9606 GN=PRRC2A PE=1 SV=3 8.75 3450.6 - 6.84E+06 - - - -1.3558 - 3.212 0.347 - 184.6 1 2 0 -0.0034 23 0 0 0 8.01E+07 6.74E+07 - - - 2.6234 1 221125_WJC_METTL3_EV_vs_WT_F03.21423.21423.2 1.09E-08 13/26 K.TGEEIFGTIGMR[166.11]PN.A "sp|Q99873|ANM1_HUMAN,tr|E9PKG1|E9PKG1_HUMAN" 2 1530.7376 2.47 36250 21423 2 1530.734687 766.3761 Protein arginine N-methyltransferase 1 OS=Homo sapiens OX=9606 GN=PRMT1 PE=1 SV=3 4.53 3450.8 - 3.27E+06 - - - -1.9017 - 2.82 0.569 - 652.9 1 1 0 -0.0029 14 0 0 0 9.17E+07 3.72E+07 - - - 5.8444 1 221125_WJC_METTL3_EV_vs_WT_F03.21424.21424.4 5.68E-06 20/96 K.LSSLIILMPHHVEPLER[166.11].L "sp|P50454|SERPH_HUMAN,tr|E9PKH2|E9PKH2_HUMAN,tr|E9PPV6|E9PPV6_HUMAN,tr|E9PR70|E9PR70_HUMAN,tr|E9PJH8|E9PJH8_HUMAN" 5 1993.1058 1.9 36251 21424 4 1993.102073 499.2837 Serpin H1 OS=Homo sapiens OX=9606 GN=SERPINH1 PE=1 SV=2 6 3450.8 - 2.20E+06 - - - -1.8815 - 3.464 0.531 - 466.6 1 2 0 -0.0037 17 0 0 0 6.75E+07 3.54E+07 - - - 4.2782 0.9999 221125_WJC_METTL3_EV_vs_WT_F03.21429.21429.3 0.000611 Dec-44 R.LLLDIPLQTPHK[136.11].L "sp|P0DJD0|RGPD1_HUMAN,sp|Q7Z3J3|RGPD4_HUMAN,sp|O14715|RGPD8_HUMAN,sp|P49792|RBP2_HUMAN,sp|P0DJD1|RGPD2_HUMAN,sp|A6NKT7|RGPD3_HUMAN,sp|Q99666|RGPD5_HUMAN,tr|A0A286YES2|A0A286YES2_HUMAN,tr|F8VYC4|F8VYC4_HUMAN,tr|J3KNE0|J3KNE0_HUMAN,tr|A0A1W2PNU4|A0A1W2PNU4_HUMAN,tr|J3KQ37|J3KQ37_HUMAN" 12 1394.8377 1.29 36256 21429 3 1394.837262 465.9532 RANBP2-like and GRIP domain-containing protein 1 OS=Homo sapiens OX=9606 GN=RGPD1 PE=2 SV=1 6.74 3451.4 - 1.00E+06 - - - -0.3047 - 2.38 0.418 - 221.1 1 2 0 -0.0004 12 0 0 0 3.54E+07 2.75E+07 - - - 5.6036 1 221125_WJC_METTL3_EV_vs_WT_F03.21432.21432.3 4.83E-10 20/68 R.LNRLPAAGVGDMVMATVK.K "sp|P62829|RL23_HUMAN,tr|J3KT29|J3KT29_HUMAN,tr|B9ZVP7|B9ZVP7_HUMAN,tr|C9JD32|C9JD32_HUMAN" 4 1841.9856 0.85 36257 21432 3 1841.983839 615.0025 60S ribosomal protein L23 OS=Homo sapiens OX=9606 GN=RPL23 PE=1 SV=1 8.75 3451.7 - 7.55E+06 - - - -0.9343 - 4.001 0.619 - 431.2 1 2 1 -0.0017 18 0 0 0 2.40E+08 2.81E+08 - - - 8.8934 1 221125_WJC_METTL3_EV_vs_WT_F03.21434.21434.2 5.52E-08 17/32 R.LEQELFSGGNTGINFEK[136.11].Y "sp|O00571|DDX3X_HUMAN,sp|O15523|DDX3Y_HUMAN,tr|A0A2R8YFR4|A0A2R8YFR4_HUMAN,tr|A0A2R8YCW1|A0A2R8YCW1_HUMAN,tr|A0A2R8YDH3|A0A2R8YDH3_HUMAN,tr|A0A2R8Y645|A0A2R8Y645_HUMAN,tr|A0A2R8YF78|A0A2R8YF78_HUMAN,tr|C9J8G5|C9J8G5_HUMAN,tr|A0A2R8YCU0|A0A2R8YCU0_HUMAN,tr|A0A0D9SFB3|A0A0D9SFB3_HUMAN,tr|A0A2R8YFS5|A0A2R8YFS5_HUMAN,tr|A0A0D9SF53|A0A0D9SF53_HUMAN,tr|A0A2R8Y650|A0A2R8Y650_HUMAN,tr|C9J081|C9J081_HUMAN,tr|A0A2R8Y5G6|A0A2R8Y5G6_HUMAN,tr|A0A0D9SG12|A0A0D9SG12_HUMAN,tr|F6S8Q4|F6S8Q4_HUMAN,tr|A0A2U3TZJ9|A0A2U3TZJ9_HUMAN,tr|A0A2R8Y4A4|A0A2R8Y4A4_HUMAN" 19 1889.9251 1.87 36259 21434 2 1889.926818 945.9698 ATP-dependent RNA helicase DDX3X OS=Homo sapiens OX=9606 GN=DDX3X PE=1 SV=3 4.25 3452 - 2.83E+06 - - - 0.9313 - 3.526 0.565 - 940.2 1 2 0 0.0018 17 0 0 0 1.10E+08 5.87E+07 - - - 6.3117 0.9996 221125_WJC_METTL3_EV_vs_WT_F03.21435.21435.3 0.0742 13/40 K.VEVQLPELFHK.L "sp|Q13303|KCAB2_HUMAN,tr|A0A590UJJ4|A0A590UJJ4_HUMAN,tr|A0A5F9UN28|A0A5F9UN28_HUMAN,tr|A0A590UJB6|A0A590UJB6_HUMAN" 4 1337.7343 1.59 36260 21435 3 1337.731824 446.9187 Voltage-gated potassium channel subunit beta-2 OS=Homo sapiens OX=9606 GN=KCNAB2 PE=1 SV=2 5.4 3452.1 - 2.37E+06 - - - -1.8785 - 2.117 0.33 - 149.2 1 2 0 -0.0025 11 0 0 0 3.62E+07 2.28E+07 - - - 4.3491 0.9996 221125_WJC_METTL3_EV_vs_WT_F03.21436.21436.2 4.02E-06 18/36 R.ILSAENIPNLPPGGGLAGK.R "sp|O75688|PPM1B_HUMAN,tr|B8ZZF0|B8ZZF0_HUMAN,tr|A0A3B3IS24|A0A3B3IS24_HUMAN,tr|C9JIR6|C9JIR6_HUMAN" 4 1817.0047 6.87 36261 21436 2 1817.000957 909.5096 Protein phosphatase 1B OS=Homo sapiens OX=9606 GN=PPM1B PE=1 SV=1 6 3452.2 - 2.15E+06 - - - -2.0594 - 2.504 0.4 - 376.5 1 2 0 -0.0037 19 0 0 0 5.19E+07 7.56E+06 - - - 4.2509 0.9999 221125_WJC_METTL3_EV_vs_WT_F03.21438.21438.2 1.46E-07 18-Dec R.EC[160.03]LNLWGYER.V sp|Q86U44|MTA70_HUMAN 1 1338.6027 0.01 36263 21438 2 1338.601269 670.3086 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 4.53 3452.4 - 1.81E+06 - - - -1.0474 - 2.16 0.579 - 759.1 1 2 0 -0.0014 10 0 0 0 1.82E+07 1.31E+09 - - - 5.4667 1 221125_WJC_METTL3_EV_vs_WT_F03.21439.21439.3 4.60E-07 13/40 R.WYEWLDPSIKK.T sp|Q99459|CDC5L_HUMAN 1 1463.7449 1.21 36264 21439 3 1463.742555 488.9222 Cell division cycle 5-like protein OS=Homo sapiens OX=9606 GN=CDC5L PE=1 SV=2 6.07 3452.5 - 1.63E+06 - - - -1.6034 - 2.499 0.548 - 272 1 2 0 -0.0023 11 0 0 0 1.46E+07 1.21E+07 - - - 7.2509 0.9956 221125_WJC_METTL3_EV_vs_WT_F03.21440.21440.3 0.0832 Aug-36 R.EC[160.03]LNLWGYER[166.11].V sp|Q86U44|MTA70_HUMAN 1 1348.6109 0.001 36265 21440 3 1348.609057 450.5443 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 4.53 3452.6 - 1.48E+06 - - - -1.397 - 1.497 0.244 - 84.9 1 2 0 -0.0019 10 0 0 0 0.00E+00 8.67E+06 - - - 2.4381 0.9999 221125_WJC_METTL3_EV_vs_WT_F03.21442.21442.2 3.35E-06 13/22 K.SEDFSLPAYMDR.R "sp|P13073|COX41_HUMAN,tr|H3BNI5|H3BNI5_HUMAN,tr|Q86WV2|Q86WV2_HUMAN,tr|H3BN72|H3BN72_HUMAN,tr|H3BNV9|H3BNV9_HUMAN" 5 1429.6184 1.46 36267 21442 2 1429.619112 715.8165 "Cytochrome c oxidase subunit 4 isoform 1, mitochondrial OS=Homo sapiens OX=9606 GN=COX4I1 PE=1 SV=1" 4.03 3452.9 - 1.18E+06 - - - 0.5113 - 2.289 0.556 - 589.1 1 2 0 0.0007 12 0 0 0 4.68E+07 3.21E+07 - - - 5.3263 1 221125_WJC_METTL3_EV_vs_WT_F03.21443.21443.3 8.42E-08 Nov-40 K.R[166.11]EEIMESILFK[136.11].C "sp|Q99700|ATX2_HUMAN,tr|A0A5F9ZHW5|A0A5F9ZHW5_HUMAN,tr|A0A5F9ZHH4|A0A5F9ZHH4_HUMAN,tr|A0A5F9ZI57|A0A5F9ZI57_HUMAN,tr|A0A2R8YDM9|A0A2R8YDM9_HUMAN,tr|F8VQP2|F8VQP2_HUMAN,tr|A0A2R8Y5A6|A0A2R8Y5A6_HUMAN,tr|F8WB06|F8WB06_HUMAN,tr|A0A5F9ZH85|A0A5F9ZH85_HUMAN,tr|V9GY86|V9GY86_HUMAN,tr|A0A2R8Y7E6|A0A2R8Y7E6_HUMAN,tr|A0A5F9ZHX3|A0A5F9ZHX3_HUMAN,tr|H0YH87|H0YH87_HUMAN,tr|A0A2R8Y7P6|A0A2R8Y7P6_HUMAN" 14 1411.75 0.65 36268 21443 3 1411.749376 471.5906 Ataxin-2 OS=Homo sapiens OX=9606 GN=ATXN2 PE=1 SV=2 4.79 3453 - 1.12E+06 - - - -0.447 - 2.376 0.55 - 223.7 1 2 0 -0.0006 11 0 0 0 5.03E+06 7.77E+06 - - - 7.1303 1 221125_WJC_METTL3_EV_vs_WT_F03.21444.21444.3 2.59E-12 21/64 K.LSSLIILMPHHVEPLER[166.11].L "sp|P50454|SERPH_HUMAN,tr|E9PKH2|E9PKH2_HUMAN,tr|E9PPV6|E9PPV6_HUMAN,tr|E9PR70|E9PR70_HUMAN,tr|E9PJH8|E9PJH8_HUMAN" 5 1993.1058 1.24 36269 21444 3 1993.103001 665.3759 Serpin H1 OS=Homo sapiens OX=9606 GN=SERPINH1 PE=1 SV=2 6 3453.1 - 720056 - - - -1.4159 - 3.841 0.513 - 799 1 2 0 -0.0028 17 0 0 0 2.15E+07 1.74E+07 - - - 7.6584 1 221125_WJC_METTL3_EV_vs_WT_F03.21445.21445.2 2.34E-07 15/34 M.ALSENSGMNPIQTMTEVR[166.11].A "sp|P48643|TCPE_HUMAN,tr|E9PCA1|E9PCA1_HUMAN,tr|B7ZAR1|B7ZAR1_HUMAN,tr|E7ENZ3|E7ENZ3_HUMAN" 4 1986.9378 0.18 36270 21445 2 1986.938629 994.4762 T-complex protein 1 subunit epsilon OS=Homo sapiens OX=9606 GN=CCT5 PE=1 SV=1 4.53 3453.3 - 531988 - - - 0.4016 - 3.078 0.637 - 593.4 1 1 0 0.0008 18 0 0 0 3.72E+06 2.05E+07 - - - 6.5097 0.9998 221125_WJC_METTL3_EV_vs_WT_F03.21448.21448.2 1.39E-05 13/24 R.SEAVVEYVFSGSR[166.11].L "sp|Q7KZF4|SND1_HUMAN,tr|H7C597|H7C597_HUMAN" 2 1438.6968 2.43 36271 21448 2 1438.698955 720.3557 Staphylococcal nuclease domain-containing protein 1 OS=Homo sapiens OX=9606 GN=SND1 PE=1 SV=1 4.53 3453.6 - 1.63E+06 - - - 1.5125 - 2.528 0.446 - 365.7 1 2 0 0.0022 13 0 0 0 3.33E+07 1.37E+07 - - - 4.7147 1 221125_WJC_METTL3_EV_vs_WT_F03.21450.21450.3 2.19E-11 26/92 R.FEEVEEEPEVIPGPPSESPGMLTK.L sp|O43395|PRPF3_HUMAN 1 2626.236 2.59 36273 21450 3 2626.234922 876.4193 U4\U6 small nuclear ribonucleoprotein Prp3 OS=Homo sapiens OX=9606 GN=PRPF3 PE=1 SV=2 3.83 3453.9 - 1.70E+06 - - - -0.4166 - 4.192 0.694 - 595.6 1 2 0 -0.0011 24 0 0 0 5.57E+07 2.15E+07 - - - 9.6058 0.9999 221125_WJC_METTL3_EV_vs_WT_F03.21451.21451.2 5.08E-06 13/22 K.SEDFSLPAYMDR[166.11].R "sp|P13073|COX41_HUMAN,tr|H3BNI5|H3BNI5_HUMAN,tr|Q86WV2|Q86WV2_HUMAN,tr|H3BN72|H3BN72_HUMAN,tr|H3BNV9|H3BNV9_HUMAN" 5 1439.6267 1.44 36274 21451 2 1439.624654 720.8206 "Cytochrome c oxidase subunit 4 isoform 1, mitochondrial OS=Homo sapiens OX=9606 GN=COX4I1 PE=1 SV=1" 4.03 3454 - 1.63E+06 - - - -1.3872 - 2.282 0.565 - 595 1 2 0 -0.002 12 0 0 0 4.64E+07 3.21E+07 - - - 5.3843 0.9998 221125_WJC_METTL3_EV_vs_WT_F03.21452.21452.2 1.75E-05 16-Sep K.AAIDWFDGK.E "sp|P35637|FUS_HUMAN,sp|Q92804|RBP56_HUMAN,tr|H3BPE7|H3BPE7_HUMAN,tr|A0A075B7D9|A0A075B7D9_HUMAN" 4 1021.4869 1.01 36275 21452 2 1021.485916 511.7507 RNA-binding protein FUS OS=Homo sapiens OX=9606 GN=FUS PE=1 SV=1 4.21 3454.1 - 1.51E+06 - - - -0.9594 - 1.897 0.446 - 227.3 1 2 0 -0.001 9 0 0 0 1.70E+07 1.68E+07 - - - 4.1872 0.9999 221125_WJC_METTL3_EV_vs_WT_F03.21453.21453.2 7.72E-05 16-Oct K.AAIDWFDGK[136.11].E "sp|P35637|FUS_HUMAN,sp|Q92804|RBP56_HUMAN,tr|H3BPE7|H3BPE7_HUMAN,tr|A0A075B7D9|A0A075B7D9_HUMAN" 4 1029.5011 1.01 36276 21453 2 1029.501596 515.7578 RNA-binding protein FUS OS=Homo sapiens OX=9606 GN=FUS PE=1 SV=1 4.21 3454.2 - 1.40E+06 - - - 0.4857 - 1.896 0.546 - 295.5 1 2 0 0.0005 9 0 0 0 1.70E+07 1.68E+07 - - - 4.9244 0.9999 221125_WJC_METTL3_EV_vs_WT_F03.21455.21455.4 0.0214 23/114 K.IAELLENVTLIHK[136.11]PVSLQPR[166.11].G "sp|Q14694|UBP10_HUMAN,tr|J3KT19|J3KT19_HUMAN" 2 2287.3383 0.75 36278 21455 4 2287.335119 572.8418 Ubiquitin carboxyl-terminal hydrolase 10 OS=Homo sapiens OX=9606 GN=USP10 PE=1 SV=2 6.76 3454.5 - 1.31E+06 - - - -1.3785 - 3.266 0.428 - 417.1 1 2 0 -0.0032 20 0 0 0 3.33E+06 4.44E+06 - - - 3.3461 0.9999 221125_WJC_METTL3_EV_vs_WT_F03.21456.21456.3 1.28E-05 15/48 R.TVHSLAC[160.03]LLTQYR[166.11].V "sp|P27708|PYR1_HUMAN,tr|F8VPD4|F8VPD4_HUMAN,tr|H7C2E4|H7C2E4_HUMAN" 3 1570.8165 0.39 36279 21456 3 1570.812404 524.6128 CAD protein OS=Homo sapiens OX=9606 GN=CAD PE=1 SV=3 7.92 3454.6 - 1.03E+06 - - - -2.6184 - 2.707 0.476 - 327.2 1 2 0 -0.0041 13 0 0 0 3.26E+06 8.37E+06 - - - 6.5458 0.9801 221125_WJC_METTL3_EV_vs_WT_F03.21458.21458.3 1.67E-07 16/48 L.DGIHLLDPDVVAR[166.11].F sp|Q86U44|MTA70_HUMAN 1 1428.76 0.01 36281 21458 3 1428.762114 477.2606 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 4.41 3454.9 - 847763 - - - 1.446 - 2.745 0.324 - 430.7 1 1 0 0.0021 13 0 0 0 1.17E+05 1.04E+07 - - - 4.8895 0.9995 221125_WJC_METTL3_EV_vs_WT_F03.21462.21462.2 0.000734 30-Aug R.GIEGTVPYVTTDYNFK.L sp|Q5SY16|NOL9_HUMAN 1 1802.8727 0.06 36285 21462 2 1802.872503 902.4436 Polynucleotide 5'-hydroxyl-kinase NOL9 OS=Homo sapiens OX=9606 GN=NOL9 PE=1 SV=1 4.37 3455.4 - 492208 - - - -0.0987 - 1.586 0.381 - 140.5 1 2 0 -0.0002 16 0 0 0 5.84E+06 1.02E+08 - - - 2.9889 0.9969 221125_WJC_METTL3_EV_vs_WT_F03.21466.21466.2 0.0384 26-Dec K.ETLTFPPEVPISEK.A sp|Q15208|STK38_HUMAN 1 1585.8239 8.22 36288 21466 2 1585.829813 793.9192 Serine\threonine-protein kinase 38 OS=Homo sapiens OX=9606 GN=STK38 PE=1 SV=1 4.25 3455.9 - 1.62E+06 - - - 3.7034 - 1.943 0.345 - 244.2 1 2 0 0.0059 14 0 0 0 6.92E+07 8.42E+06 - - - 3.2542 1 221125_WJC_METTL3_EV_vs_WT_F03.21470.21470.3 6.15E-10 Dec-44 R.FHDNFGFDDLVR.D sp|O00165|HAX1_HUMAN 1 1480.6735 1.3 36292 21470 3 1480.673387 494.5651 HCLS1-associated protein X-1 OS=Homo sapiens OX=9606 GN=HAX1 PE=1 SV=2 4.41 3456.2 - 1.46E+06 - - - -0.0952 - 2.5 0.665 - 180.5 1 2 0 -0.0001 12 0 0 0 5.05E+07 3.90E+07 - - - 8.4939 0.9931 221125_WJC_METTL3_EV_vs_WT_F03.21471.21471.2 3.93E-06 13/24 A.QISALEEQLQQIR.A "sp|P13645|K1C10_HUMAN,tr|A0A1B0GVI3|A0A1B0GVI3_HUMAN" 2 1554.8366 999 36293 21471 2 1554.835549 778.4256 "Keratin, type I cytoskeletal 10 OS=Homo sapiens OX=9606 GN=KRT10 PE=1 SV=6" 4.53 3456.4 - 1.19E+06 - - - -0.6567 - 2.548 0.488 - 545.3 1 1 0 -0.001 13 0 0 0 8.31E+06 0.00E+00 - - - 5.0455 0.9998 221125_WJC_METTL3_EV_vs_WT_F03.21472.21472.2 0.000538 22-Jul K.NNALNQVVLWDK.L sp|P61009|SPCS3_HUMAN 1 1412.7412 2.08 36294 21472 2 1412.74214 707.3779 Signal peptidase complex subunit 3 OS=Homo sapiens OX=9606 GN=SPCS3 PE=1 SV=1 5.84 3456.4 - 1.13E+06 - - - 0.6562 - 1.981 0.425 - 179.8 1 2 0 0.0009 12 0 0 0 8.64E+06 4.15E+06 - - - 3.9784 1 221125_WJC_METTL3_EV_vs_WT_F03.21473.21473.3 1.44E-08 21/76 K.IGPILDTNALQGEVKPVLQK.L "sp|P30154|2AAB_HUMAN,tr|H0YDG7|H0YDG7_HUMAN" 2 2132.2205 1.02 36295 21473 3 2132.222161 711.7474 Serine\threonine-protein phosphatase 2A 65 kDa regulatory subunit A beta isoform OS=Homo sapiens OX=9606 GN=PPP2R1B PE=1 SV=3 6.07 3456.6 - 1.07E+06 - - - 0.7767 - 3.273 0.537 - 402.1 1 2 0 0.0017 20 0 0 0 4.77E+06 4.68E+06 - - - 7.4031 1 221125_WJC_METTL3_EV_vs_WT_F03.21475.21475.3 2.96E-08 18/52 R.EEGTPLTLYYSHWR[166.11].K sp|Q9Y3T9|NOC2L_HUMAN 1 1760.8398 0.27 36297 21475 3 1760.842938 587.9539 Nucleolar complex protein 2 homolog OS=Homo sapiens OX=9606 GN=NOC2L PE=1 SV=4 5.4 3456.8 - 1.06E+06 - - - 1.8077 - 2.99 0.579 - 339.2 1 2 0 0.0032 14 0 0 0 3.30E+06 1.21E+07 - - - 7.9051 0.9998 221125_WJC_METTL3_EV_vs_WT_F03.21476.21476.3 0.00136 13/60 K.GQYISPFHDIPIYADK[136.11].D "sp|Q15181|IPYR_HUMAN,tr|Q5SQT6|Q5SQT6_HUMAN" 2 1870.9345 1.61 36298 21476 3 1870.930049 624.6521 Inorganic pyrophosphatase OS=Homo sapiens OX=9606 GN=PPA1 PE=1 SV=2 5.21 3456.9 - 736170 - - - -2.379 - 2.89 0.349 - 204.3 1 2 0 -0.0045 16 0 0 0 7.81E+06 4.87E+06 - - - 5.1528 0.9962 221125_WJC_METTL3_EV_vs_WT_F03.21478.21478.3 0.0737 Dec-72 R.ILSAENIPNLPPGGGLAGK[136.11].R "sp|O75688|PPM1B_HUMAN,tr|B8ZZF0|B8ZZF0_HUMAN,tr|A0A3B3IS24|A0A3B3IS24_HUMAN,tr|C9JIR6|C9JIR6_HUMAN" 4 1825.0189 7.17 36300 21478 3 1825.022079 609.3469 Protein phosphatase 1B OS=Homo sapiens OX=9606 GN=PPM1B PE=1 SV=1 6 3457.2 - 588323 - - - 1.7424 - 2.03 0.22 - 162.1 1 2 0 0.0032 19 0 0 0 6.97E+07 9.73E+06 - - - 2.7314 0.9996 221125_WJC_METTL3_EV_vs_WT_F03.21479.21479.2 2.57E-06 26-Dec K.NTSLPPLWSPEAER[166.11].S sp|P49790|NU153_HUMAN 1 1605.8026 1.45 36301 21479 2 1605.798579 803.9086 Nuclear pore complex protein Nup153 OS=Homo sapiens OX=9606 GN=NUP153 PE=1 SV=2 4.53 3457.3 - 517353 - - - -2.5296 - 2.119 0.499 - 359.9 1 2 0 -0.0041 14 0 0 0 6.44E+07 4.42E+07 - - - 4.6098 0.9999 221125_WJC_METTL3_EV_vs_WT_F03.21480.21480.2 8.64E-08 13/42 K.SISISVAGGGGGFGAAGGFGGR.G sp|P35908|K22E_HUMAN 1 1837.9071 21.65 36302 21480 2 1837.907744 919.9608 "Keratin, type II cytoskeletal 2 epidermal OS=Homo sapiens OX=9606 GN=KRT2 PE=1 SV=2" 9.47 3457.4 - 411365 - - - 0.345 - 2.608 0.535 - 295.3 1 2 0 0.0006 22 0 0 0 3.13E+07 1.45E+06 - - - 5.349 0.9999 221125_WJC_METTL3_EV_vs_WT_F03.21481.21481.3 0.000342 Oct-40 K.DIPVVHQLLTR[166.11].Y "sp|P30419|NMT1_HUMAN,tr|A0A7I2V3X4|A0A7I2V3X4_HUMAN,tr|A0A7I2V539|A0A7I2V539_HUMAN" 3 1299.7538 0.09 36303 21481 3 1299.754031 434.2586 Glycylpeptide N-tetradecanoyltransferase 1 OS=Homo sapiens OX=9606 GN=NMT1 PE=1 SV=2 6.74 3457.6 - 359185 - - - 0.1462 - 2.15 0.39 - 110.3 1 2 0 0.0002 11 0 0 0 4.68E+05 5.09E+06 - - - 5.0626 1 221125_WJC_METTL3_EV_vs_WT_F03.21485.21485.3 1.79E-08 19/48 R.KVESLQEEIAFLK.K "sp|P08670|VIME_HUMAN,tr|B0YJC5|B0YJC5_HUMAN,tr|B0YJC4|B0YJC4_HUMAN" 3 1532.845 2.03 36306 21485 3 1532.847235 511.9556 Vimentin OS=Homo sapiens OX=9606 GN=VIM PE=1 SV=4 4.79 3457.9 - 9.64E+06 - - - 1.4515 - 3.497 0.558 - 944.5 1 2 0 0.0022 13 0 0 0 1.26E+09 6.19E+08 - - - 8.1548 1 221125_WJC_METTL3_EV_vs_WT_F03.21489.21489.3 1.35E-06 21/64 K.LSSLIILMPHHVEPLER.L "sp|P50454|SERPH_HUMAN,tr|E9PKH2|E9PKH2_HUMAN,tr|E9PPV6|E9PPV6_HUMAN,tr|E9PR70|E9PR70_HUMAN,tr|E9PJH8|E9PJH8_HUMAN" 5 1983.0976 1.24 36310 21489 3 1983.100394 662.0398 Serpin H1 OS=Homo sapiens OX=9606 GN=SERPINH1 PE=1 SV=2 6 3458.2 - 1.27E+06 - - - 1.4326 - 4.536 0.527 - 847.3 1 2 0 0.0028 17 0 0 0 2.15E+07 1.74E+07 - - - 8.2346 0.9999 221125_WJC_METTL3_EV_vs_WT_F03.21490.21490.3 0.000678 14/68 R.AAIAQALAGEVSVVPPSR[166.11].L sp|Q2TAY7|SMU1_HUMAN 1 1744.9711 0.85 36311 21490 3 1744.974423 582.6643 WD40 repeat-containing protein SMU1 OS=Homo sapiens OX=9606 GN=SMU1 PE=1 SV=2 6.05 3458.3 - 1.11E+06 - - - 1.902 - 3.065 0.367 - 200.9 1 2 0 0.0033 18 0 0 0 4.44E+07 5.25E+07 - - - 5.4198 0.9981 221125_WJC_METTL3_EV_vs_WT_F03.21494.21494.3 9.82E-06 14/64 K.EFPGFLENQK[136.11]DPLAVDK[136.11].L sp|P60903|S10AA_HUMAN 1 1962.0069 -1 36315 21494 3 1962.013891 655.0096 Protein S100-A10 OS=Homo sapiens OX=9606 GN=S100A10 PE=1 SV=2 4.32 3458.8 - 709618 - - - 3.5413 - 2.976 0.378 - 210.5 1 2 1 0.0069 17 0 0 0 0.00E+00 0.00E+00 - - - 5.5075 0.9997 221125_WJC_METTL3_EV_vs_WT_F03.21496.21496.2 2.68E-06 15/36 R.ILSAENIPNLPPGGGLAGK[136.11].R "sp|O75688|PPM1B_HUMAN,tr|B8ZZF0|B8ZZF0_HUMAN,tr|A0A3B3IS24|A0A3B3IS24_HUMAN,tr|C9JIR6|C9JIR6_HUMAN" 4 1825.0189 6.5 36317 21496 2 1825.021823 913.5167 Protein phosphatase 1B OS=Homo sapiens OX=9606 GN=PPM1B PE=1 SV=1 6 3459 - 548046 - - - 1.6022 - 2.666 0.395 - 342.7 1 2 0 0.0029 19 0 0 0 5.97E+07 9.19E+06 - - - 4.3684 0.9876 221125_WJC_METTL3_EV_vs_WT_F03.21499.21499.3 0.307 Oct-72 R.ILSAENIPNLPPGGGLAGK.R "sp|O75688|PPM1B_HUMAN,tr|B8ZZF0|B8ZZF0_HUMAN,tr|A0A3B3IS24|A0A3B3IS24_HUMAN,tr|C9JIR6|C9JIR6_HUMAN" 4 1817.0047 6.2 36319 21499 3 1817.005958 606.6755 Protein phosphatase 1B OS=Homo sapiens OX=9606 GN=PPM1B PE=1 SV=1 6 3459.4 - 3.18E+06 - - - 0.6929 - 1.508 0.191 - 55 1 2 0 0.0013 19 0 0 0 9.12E+07 1.47E+07 - - - 1.6783 1 221125_WJC_METTL3_EV_vs_WT_F03.21501.21501.3 7.34E-07 Dec-44 R.FHDNFGFDDLVR[166.11].D sp|O00165|HAX1_HUMAN 1 1490.6818 1.39 36321 21501 3 1490.682891 497.9012 HCLS1-associated protein X-1 OS=Homo sapiens OX=9606 GN=HAX1 PE=1 SV=2 4.41 3459.6 - 7.36E+06 - - - 0.7332 - 2.415 0.556 - 158.4 1 2 0 0.0011 12 0 0 0 5.05E+07 3.63E+07 - - - 7.1825 1 221125_WJC_METTL3_EV_vs_WT_F03.21502.21502.2 1.69E-09 19/24 R.KVESLQEEIAFLK.K "sp|P08670|VIME_HUMAN,tr|B0YJC5|B0YJC5_HUMAN,tr|B0YJC4|B0YJC4_HUMAN" 3 1532.845 1.99 36322 21502 2 1532.846884 767.4298 Vimentin OS=Homo sapiens OX=9606 GN=VIM PE=1 SV=4 4.79 3459.6 - 5.54E+06 - - - 1.2226 - 4.254 0.618 - 1090.2 1 2 0 0.0019 13 0 0 0 2.53E+08 1.27E+08 - - - 7.3209 1 221125_WJC_METTL3_EV_vs_WT_F03.21503.21503.2 0.00256 16/24 R.K[136.11]VESLQEEIAFLK[136.11].K "sp|P08670|VIME_HUMAN,tr|B0YJC5|B0YJC5_HUMAN,tr|B0YJC4|B0YJC4_HUMAN" 3 1548.8734 1.99 36323 21503 2 1548.873986 775.444 Vimentin OS=Homo sapiens OX=9606 GN=VIM PE=1 SV=4 4.79 3459.7 - 3.51E+06 - - - 0.3719 - 3.854 0.587 - 660.9 1 2 0 0.0006 13 0 0 0 2.53E+08 1.27E+08 - - - 6.8389 0.9999 221125_WJC_METTL3_EV_vs_WT_F03.21504.21504.3 2.60E-05 15/68 K.RPAVPAAVSLLPPADPLR.Q sp|Q9H7S9|ZN703_HUMAN 1 1839.0731 1.98 36324 21504 3 1839.070773 614.0316 Zinc finger protein 703 OS=Homo sapiens OX=9606 GN=ZNF703 PE=1 SV=1 9.6 3459.7 - 3.06E+06 - - - -1.2398 - 2.815 0.433 - 247.9 1 2 0 -0.0023 18 0 0 0 1.28E+07 6.46E+06 - - - 5.9441 1 221125_WJC_METTL3_EV_vs_WT_F03.21505.21505.4 7.00E-11 28/114 K.IALLNVELELK[136.11]AEK[136.11]DNAEIR[166.11].V sp|Q99832|TCPH_HUMAN 1 2306.3056 0.13 36325 21505 4 2306.305998 577.5837 T-complex protein 1 subunit eta OS=Homo sapiens OX=9606 GN=CCT7 PE=1 SV=2 4.59 3459.8 - 2.90E+06 - - - 0.1804 - 4.644 0.616 - 709.3 1 2 2 0.0004 20 0 0 0 1.05E+06 8.21E+06 - - - 5.1009 0.9995 221125_WJC_METTL3_EV_vs_WT_F03.21506.21506.3 7.29E-06 Dec-56 R.LFGHSSTSALSAILR[166.11].S sp|Q7Z6Z7|HUWE1_HUMAN 1 1568.855 0.59 36326 21506 3 1568.856712 523.9589 E3 ubiquitin-protein ligase HUWE1 OS=Homo sapiens OX=9606 GN=HUWE1 PE=1 SV=3 9.76 3459.8 - 1.82E+06 - - - 1.0842 - 2.304 0.292 - 179.2 1 2 0 0.0017 15 0 0 0 3.75E+06 6.35E+06 - - - 3.9729 1 221125_WJC_METTL3_EV_vs_WT_F03.21507.21507.3 4.13E-07 15/60 K.VLAQNSGFDLQETLVK[136.11].L sp|P40227|TCPZ_HUMAN 1 1768.9451 0.34 36327 21507 3 1768.947595 590.6556 T-complex protein 1 subunit zeta OS=Homo sapiens OX=9606 GN=CCT6A PE=1 SV=3 4.37 3459.9 - 1.77E+06 - - - 1.4302 - 2.692 0.531 - 209.5 1 2 0 0.0025 16 0 0 0 1.83E+07 5.36E+07 - - - 7.0004 1 221125_WJC_METTL3_EV_vs_WT_F03.21508.21508.2 2.18E-06 13/24 R.ANDQEPC[160.03]GWWLAK[136.11].V "sp|P51114|FXR1_HUMAN,tr|E9PFF5|E9PFF5_HUMAN,tr|C9JAJ4|C9JAJ4_HUMAN,tr|B4DXZ6|B4DXZ6_HUMAN" 4 1581.7126 260.71 36328 21508 2 1581.712226 791.8636 Fragile X mental retardation syndrome-related protein 1 OS=Homo sapiens OX=9606 GN=FXR1 PE=1 SV=3 4.37 3460 - 1.73E+06 - - - -0.2131 - 2.919 0.578 - 565 1 2 0 -0.0003 13 0 0 0 4.11E+09 1.58E+07 - - - 6.0594 1 221125_WJC_METTL3_EV_vs_WT_F03.21509.21509.3 1.80E-05 19/64 R.LQVTNVLSQPLTQATVK[136.11].L "sp|P04844|RPN2_HUMAN,tr|Q5JYR7|Q5JYR7_HUMAN,tr|Q5JYR4|Q5JYR4_HUMAN" 3 1847.0608 1.08 36329 21509 3 1847.061587 616.6942 Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit 2 OS=Homo sapiens OX=9606 GN=RPN2 PE=1 SV=3 8.75 3460.1 - 1.49E+06 - - - 0.4461 - 2.916 0.46 - 330.8 1 2 0 0.0008 17 0 0 0 3.71E+07 3.44E+07 - - - 6.372 1 221125_WJC_METTL3_EV_vs_WT_F03.21511.21511.3 6.30E-06 17/68 K.R[166.11]PAVPAAVSLLPPADPLR[166.11].Q sp|Q9H7S9|ZN703_HUMAN 1 1859.0896 1.78 36331 21511 3 1859.090392 620.7038 Zinc finger protein 703 OS=Homo sapiens OX=9606 GN=ZNF703 PE=1 SV=1 9.6 3460.3 - 1.34E+06 - - - 0.4298 - 2.756 0.549 - 310 1 2 0 0.0008 18 0 0 0 1.13E+08 6.37E+07 - - - 7.185 0.9995 221125_WJC_METTL3_EV_vs_WT_F03.21512.21512.3 2.02E-05 15/68 R.TVITPDPNLSIDQVGVPR[166.11].S "sp|P24928|RPB1_HUMAN,tr|A0A6Q8PGB0|A0A6Q8PGB0_HUMAN" 2 1930.0399 -1 36332 21512 3 1930.029814 644.3539 DNA-directed RNA polymerase II subunit RPB1 OS=Homo sapiens OX=9606 GN=POLR2A PE=1 SV=2 4.21 3460.3 - 1.33E+06 - - - -5.232 - 2.763 0.499 - 208.2 1 2 0 -0.0101 18 0 0 0 0.00E+00 0.00E+00 - - - 6.6313 0.9998 221125_WJC_METTL3_EV_vs_WT_F03.21513.21513.2 0.000138 15/34 R.TVITPDPNLSIDQVGVPR.S "sp|P24928|RPB1_HUMAN,tr|A0A6Q8PGB0|A0A6Q8PGB0_HUMAN" 2 1920.0316 1.83 36333 21513 2 1920.035131 961.0231 DNA-directed RNA polymerase II subunit RPB1 OS=Homo sapiens OX=9606 GN=POLR2A PE=1 SV=2 4.21 3460.5 - 1.20E+06 - - - 1.8172 - 2.918 0.525 - 657.8 1 2 0 0.0035 18 0 0 0 7.46E+06 4.08E+06 - - - 5.5504 0.9998 221125_WJC_METTL3_EV_vs_WT_F03.21516.21516.2 2.10E-05 14/26 K.AAILPTSIFLTNKK.G "sp|O14744|ANM5_HUMAN,tr|H0YJX6|H0YJX6_HUMAN" 2 1515.9025 5.49 36336 21516 2 1515.904547 758.9585 Protein arginine N-methyltransferase 5 OS=Homo sapiens OX=9606 GN=PRMT5 PE=1 SV=4 10 3460.8 - 1.04E+06 - - - 1.3734 - 2.741 0.498 - 488.3 1 2 0 0.0021 14 0 0 0 1.34E+07 2.44E+06 - - - 5.2489 0.9995 221125_WJC_METTL3_EV_vs_WT_F03.21517.21517.3 0.0151 Nov-40 K.VEVQLPELFHK[136.11].L "sp|Q13303|KCAB2_HUMAN,tr|A0A590UJJ4|A0A590UJJ4_HUMAN,tr|A0A5F9UN28|A0A5F9UN28_HUMAN,tr|A0A590UJB6|A0A590UJB6_HUMAN" 4 1345.7485 1.61 36337 21517 3 1345.747898 449.5901 Voltage-gated potassium channel subunit beta-2 OS=Homo sapiens OX=9606 GN=KCNAB2 PE=1 SV=2 5.4 3461 - 963606 - - - -0.4748 - 2.291 0.262 - 214.5 1 2 0 -0.0006 11 0 0 0 3.62E+07 2.24E+07 - - - 3.8159 1 221125_WJC_METTL3_EV_vs_WT_F03.21518.21518.2 7.46E-11 14/22 R.FHDNFGFDDLVR.D sp|O00165|HAX1_HUMAN 1 1480.6735 2.08 36338 21518 2 1480.673293 741.344 HCLS1-associated protein X-1 OS=Homo sapiens OX=9606 GN=HAX1 PE=1 SV=2 4.41 3461.1 - 953528 - - - -0.1587 - 2.698 0.661 - 731.4 1 2 0 -0.0002 12 0 0 0 7.70E+06 3.69E+06 - - - 6.5345 0.9999 221125_WJC_METTL3_EV_vs_WT_F03.21522.21522.2 3.39E-05 22-Nov K.DAGTIAGLNVLR[166.11].L "sp|P11142|HSP7C_HUMAN,tr|E9PQQ4|E9PQQ4_HUMAN,tr|E9PKE3|E9PKE3_HUMAN,tr|E9PN89|E9PN89_HUMAN,tr|E9PLF4|E9PLF4_HUMAN,tr|E9PI65|E9PI65_HUMAN,tr|E9PK54|E9PK54_HUMAN,tr|E9PQK7|E9PQK7_HUMAN" 8 1208.6753 0.18 36341 21522 2 1208.674229 605.3449 Heat shock cognate 71 kDa protein OS=Homo sapiens OX=9606 GN=HSPA8 PE=1 SV=1 5.84 3461.5 - 1.74E+07 - - - -0.8497 - 2.593 0.561 - 420.1 1 2 0 -0.001 12 0 0 0 8.69E+07 4.91E+08 - - - 5.6912 1 221125_WJC_METTL3_EV_vs_WT_F03.21523.21523.2 3.71E-10 16/30 K.VLAQNSGFDLQETLVK[136.11].L sp|P40227|TCPZ_HUMAN 1 1768.9451 0.41 36342 21523 2 1768.943027 885.4798 T-complex protein 1 subunit zeta OS=Homo sapiens OX=9606 GN=CCT6A PE=1 SV=3 4.37 3461.5 - 1.35E+07 - - - -1.1521 - 3.442 0.625 - 697.6 1 2 0 -0.002 16 0 0 0 6.32E+07 1.55E+08 - - - 6.6955 0.9853 221125_WJC_METTL3_EV_vs_WT_F03.21525.21525.3 0.0115 20/60 W.GNVGFVFTKEDLTEIR.D "sp|Q8NHW5|RLA0L_HUMAN,sp|P05388|RLA0_HUMAN,tr|G3V210|G3V210_HUMAN,tr|F8VU65|F8VU65_HUMAN,tr|F8VWV4|F8VWV4_HUMAN,tr|F8VWS0|F8VWS0_HUMAN,tr|F8VS58|F8VS58_HUMAN,tr|F8VW21|F8VW21_HUMAN,tr|F8VZS0|F8VZS0_HUMAN,tr|F8VRK7|F8VRK7_HUMAN,tr|F8VQY6|F8VQY6_HUMAN,tr|F8VPE8|F8VPE8_HUMAN" 12 1823.9418 0.5 36344 21525 3 1823.936915 608.9879 60S acidic ribosomal protein P0-like OS=Homo sapiens OX=9606 GN=RPLP0P6 PE=5 SV=1 4.68 3461.6 - 4.86E+06 - - - -2.6585 - 3.708 0.562 - 590.6 1 1 1 -0.0048 16 0 0 0 5.12E+07 1.01E+08 - - - 8.1669 0.9999 221125_WJC_METTL3_EV_vs_WT_F03.21526.21526.2 3.96E-05 20-Sep K.EDFDSLLQSAK.K "sp|P08195|4F2_HUMAN,tr|A0A7P0TAN7|A0A7P0TAN7_HUMAN,tr|J3KPF3|J3KPF3_HUMAN,tr|F5H056|F5H056_HUMAN,tr|H0YH36|H0YH36_HUMAN,tr|A0A7P0TAT7|A0A7P0TAT7_HUMAN,tr|F5GZI0|F5GZI0_HUMAN,tr|A0A7P0T8U7|A0A7P0T8U7_HUMAN,tr|A0A7P0T9F7|A0A7P0T9F7_HUMAN,tr|A0A7P0TBF8|A0A7P0TBF8_HUMAN,tr|A0A7P0T8F1|A0A7P0T8F1_HUMAN,tr|A0A7P0Z4A0|A0A7P0Z4A0_HUMAN,tr|F5GZS6|F5GZS6_HUMAN,tr|A0A7P0Z4P5|A0A7P0Z4P5_HUMAN,tr|A0A7P0TAS6|A0A7P0TAS6_HUMAN" 15 1251.5983 1.52 36345 21526 2 1251.597242 626.8064 4F2 cell-surface antigen heavy chain OS=Homo sapiens OX=9606 GN=SLC3A2 PE=1 SV=3 4.03 3461.7 - 3.13E+06 - - - -0.8429 - 1.867 0.537 - 226.9 1 2 0 -0.0011 11 0 0 0 1.32E+07 8.68E+06 - - - 4.6959 1 221125_WJC_METTL3_EV_vs_WT_F03.21527.21527.3 3.58E-06 18/68 R.AAIAQALAGEVSVVPPSR.L sp|Q2TAY7|SMU1_HUMAN 1 1734.9628 0.82 36346 21527 3 1734.960464 579.3282 WD40 repeat-containing protein SMU1 OS=Homo sapiens OX=9606 GN=SMU1 PE=1 SV=2 6.05 3461.7 - 3.05E+06 - - - -1.366 - 3.343 0.527 - 283.4 1 2 0 -0.0024 18 0 0 0 4.04E+07 4.95E+07 - - - 7.4201 0.9999 221125_WJC_METTL3_EV_vs_WT_F03.21528.21528.3 0.000206 Dec-64 K.EFPGFLENQKDPLAVDK.L sp|P60903|S10AA_HUMAN 1 1945.9785 3.86 36347 21528 3 1945.978218 649.6668 Protein S100-A10 OS=Homo sapiens OX=9606 GN=S100A10 PE=1 SV=2 4.32 3461.8 - 2.85E+06 - - - -0.167 - 2.482 0.506 - 141.4 1 2 1 -0.0003 17 0 0 0 1.05E+08 2.73E+07 - - - 6.4779 1 221125_WJC_METTL3_EV_vs_WT_F03.21529.21529.2 6.68E-13 18/28 L.TTDNANILLQIDNAR.L "sp|P13645|K1C10_HUMAN,tr|A0A1B0GVI3|A0A1B0GVI3_HUMAN" 2 1670.8588 999 36348 21529 2 1670.856125 836.4367 "Keratin, type I cytoskeletal 10 OS=Homo sapiens OX=9606 GN=KRT10 PE=1 SV=6" 4.21 3461.9 - 2.24E+06 - - - -1.5788 - 3.711 0.686 - 1081.3 1 1 0 -0.0026 15 0 0 0 3.35E+07 0.00E+00 - - - 7.3309 0.9995 221125_WJC_METTL3_EV_vs_WT_F03.21530.21530.3 0.000768 Oct-60 R.IFGESIMIGVKPC[160.03]IDK.S sp|Q8NFH5|NUP35_HUMAN 1 1805.942 2.26 36349 21530 3 1805.938233 602.9879 Nucleoporin NUP35 OS=Homo sapiens OX=9606 GN=NUP35 PE=1 SV=1 6.06 3461.9 - 2.11E+06 - - - -2.066 - 1.915 0.364 - 99.1 1 2 0 -0.0037 16 0 0 0 1.18E+07 5.21E+06 - - - 4.2643 0.9999 221125_WJC_METTL3_EV_vs_WT_F03.21531.21531.3 7.33E-05 Dec-44 K.SKDWVFLNYTYK.R sp|Q9Y2H1|ST38L_HUMAN 1 1562.7769 2.81 36350 21531 3 1562.776255 521.9329 Serine\threonine-protein kinase 38-like OS=Homo sapiens OX=9606 GN=STK38L PE=1 SV=3 8.15 3462 - 2.11E+06 - - - -0.4319 - 2.391 0.493 - 167 1 2 1 -0.0007 12 0 0 0 3.92E+07 1.39E+07 - - - 6.4525 1 221125_WJC_METTL3_EV_vs_WT_F03.21532.21532.3 1.05E-11 17/60 K.VLAQNSGFDLQETLVK.L sp|P40227|TCPZ_HUMAN 1 1760.9309 0.35 36351 21532 3 1760.926181 587.9842 T-complex protein 1 subunit zeta OS=Homo sapiens OX=9606 GN=CCT6A PE=1 SV=3 4.37 3462 - 2.07E+06 - - - -2.66 - 3.609 0.628 - 480.2 1 2 0 -0.0047 16 0 0 0 1.83E+07 5.31E+07 - - - 8.8334 1 221125_WJC_METTL3_EV_vs_WT_F03.21534.21534.2 2.83E-06 18/32 R.LQVTNVLSQPLTQATVK[136.11].L "sp|P04844|RPN2_HUMAN,tr|Q5JYR7|Q5JYR7_HUMAN,tr|Q5JYR4|Q5JYR4_HUMAN" 3 1847.0608 1.24 36353 21534 2 1847.058938 924.5377 Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit 2 OS=Homo sapiens OX=9606 GN=RPN2 PE=1 SV=3 8.75 3462.2 - 1.53E+06 - - - -0.9881 - 3.408 0.572 - 765.6 1 2 0 -0.0018 17 0 0 0 2.10E+07 1.69E+07 - - - 6.2797 0.9998 221125_WJC_METTL3_EV_vs_WT_F03.21535.21535.2 1.72E-05 24-Oct R.DLTQNTVVSINFK[136.11].D sp|Q9H0D6|XRN2_HUMAN 1 1485.7919 0.57 36354 21535 2 1485.791104 743.9032 5'-3' exoribonuclease 2 OS=Homo sapiens OX=9606 GN=XRN2 PE=1 SV=1 5.84 3462.3 - 1.52E+06 - - - -0.5081 - 2.171 0.426 - 304.5 1 2 0 -0.0008 13 0 0 0 6.01E+06 1.05E+07 - - - 4.1767 1 221125_WJC_METTL3_EV_vs_WT_F03.21537.21537.3 1.71E-05 Nov-44 K.DHIMEIFSTYGK[136.11].L "sp|Q15287|RNPS1_HUMAN,tr|H3BMM9|H3BMM9_HUMAN,tr|H3BV80|H3BV80_HUMAN,tr|H3BMS0|H3BMS0_HUMAN,tr|H3BTC0|H3BTC0_HUMAN" 5 1447.6897 1.34 36356 21537 3 1447.688833 483.5705 RNA-binding protein with serine-rich domain 1 OS=Homo sapiens OX=9606 GN=RNPS1 PE=1 SV=1 5.32 3462.6 - 928760 - - - -0.6003 - 2.181 0.553 - 159 1 2 0 -0.0009 12 0 0 0 3.66E+07 2.72E+07 - - - 6.8666 0.9996 221125_WJC_METTL3_EV_vs_WT_F03.21538.21538.2 1.74E-09 22-Oct K.DTPDEPWAFPAR[166.11].E sp|Q7KZF4|SND1_HUMAN 1 1410.6444 0.47 36357 21538 2 1410.639949 706.3295 Staphylococcal nuclease domain-containing protein 1 OS=Homo sapiens OX=9606 GN=SND1 PE=1 SV=1 4.03 3462.7 - 919342 - - - -3.1199 - 2.167 0.608 - 331.8 1 2 0 -0.0044 12 0 0 0 4.99E+06 1.07E+07 - - - 5.5651 1 221125_WJC_METTL3_EV_vs_WT_F03.21541.21541.3 0.00232 17/52 K.AAILPTSIFLTNKK.G "sp|O14744|ANM5_HUMAN,tr|H0YJX6|H0YJX6_HUMAN" 2 1515.9025 3.22 36359 21541 3 1515.902551 506.3081 Protein arginine N-methyltransferase 5 OS=Homo sapiens OX=9606 GN=PRMT5 PE=1 SV=4 10 3463 - 4.83E+07 - - - 0.0567 - 3.137 0.484 - 626 1 2 0 0.0001 14 0 0 0 2.28E+08 7.09E+07 - - - 6.9744 1 221125_WJC_METTL3_EV_vs_WT_F03.21542.21542.2 0.0121 23/34 R.AAIAQALAGEVSVVPPSR.L sp|Q2TAY7|SMU1_HUMAN 1 1734.9628 1.22 36360 21542 2 1734.95937 868.4887 WD40 repeat-containing protein SMU1 OS=Homo sapiens OX=9606 GN=SMU1 PE=1 SV=2 6.05 3463.2 - 1.02E+06 - - - -1.9966 - 4.032 0.58 - 1302.9 1 2 0 -0.0035 18 0 0 0 6.66E+06 5.46E+06 - - - 6.7517 1 221125_WJC_METTL3_EV_vs_WT_F03.21543.21543.2 1.59E-11 16/30 K.VLAQNSGFDLQETLVK.L sp|P40227|TCPZ_HUMAN 1 1760.9309 0.41 36361 21543 2 1760.929369 881.4727 T-complex protein 1 subunit zeta OS=Homo sapiens OX=9606 GN=CCT6A PE=1 SV=3 4.37 3463.2 - 1.16E+07 - - - -0.8496 - 3.401 0.652 - 643 1 2 0 -0.0015 16 0 0 0 6.32E+07 1.55E+08 - - - 6.8656 0.9998 221125_WJC_METTL3_EV_vs_WT_F03.21544.21544.2 0.00326 22-Nov K.DAGTIAGLNVLR.L "sp|P11142|HSP7C_HUMAN,tr|E9PQQ4|E9PQQ4_HUMAN,tr|E9PKE3|E9PKE3_HUMAN,tr|E9PN89|E9PN89_HUMAN,tr|E9PLF4|E9PLF4_HUMAN,tr|E9PI65|E9PI65_HUMAN,tr|E9PK54|E9PK54_HUMAN,tr|E9PQK7|E9PQK7_HUMAN" 8 1198.667 0.18 36362 21544 2 1198.666147 600.3408 Heat shock cognate 71 kDa protein OS=Homo sapiens OX=9606 GN=HSPA8 PE=1 SV=1 5.84 3463.2 - 6.93E+06 - - - -0.6999 - 2.229 0.437 - 379.9 1 2 0 -0.0008 12 0 0 0 8.69E+07 4.94E+08 - - - 4.3774 0.9995 221125_WJC_METTL3_EV_vs_WT_F03.21545.21545.2 0.000122 26-Oct K.NTSLPPLWSPEAER.S sp|P49790|NU153_HUMAN 1 1595.7944 1.45 36363 21545 2 1595.79058 798.9045 Nuclear pore complex protein Nup153 OS=Homo sapiens OX=9606 GN=NUP153 PE=1 SV=2 4.53 3463.3 - 5.05E+06 - - - -2.3756 - 1.955 0.497 - 206.4 1 2 0 -0.0038 14 0 0 0 6.44E+07 4.42E+07 - - - 4.393 0.9725 221125_WJC_METTL3_EV_vs_WT_F03.21546.21546.3 0.0023 13/56 L.TTDNANILLQIDNAR.L "sp|P13645|K1C10_HUMAN,tr|A0A1B0GVI3|A0A1B0GVI3_HUMAN" 2 1670.8588 999 36364 21546 3 1670.855502 557.9602 "Keratin, type I cytoskeletal 10 OS=Homo sapiens OX=9606 GN=KRT10 PE=1 SV=6" 4.21 3463.3 - 3.25E+06 - - - -1.9517 - 2.006 0.398 - 184.7 1 1 0 -0.0033 15 0 0 0 1.85E+07 0.00E+00 - - - 4.7929 1 221125_WJC_METTL3_EV_vs_WT_F03.21547.21547.3 1.80E-07 Oct-44 K.DHIMEIFSTYGK.L "sp|Q15287|RNPS1_HUMAN,tr|H3BMM9|H3BMM9_HUMAN,tr|H3BV80|H3BV80_HUMAN,tr|H3BMS0|H3BMS0_HUMAN,tr|H3BTC0|H3BTC0_HUMAN" 5 1439.6755 1.34 36365 21547 3 1439.675196 480.8991 RNA-binding protein with serine-rich domain 1 OS=Homo sapiens OX=9606 GN=RNPS1 PE=1 SV=1 5.32 3463.4 - 2.86E+06 - - - -0.2125 - 2.109 0.639 - 150.4 1 2 0 -0.0003 12 0 0 0 3.66E+07 2.72E+07 - - - 7.7325 1 221125_WJC_METTL3_EV_vs_WT_F03.21548.21548.2 4.94E-06 16/22 K.WELLQQVDTSTR.T sp|P04264|K2C1_HUMAN 1 1474.7416 -1 36366 21548 2 1474.740032 738.3781 "Keratin, type II cytoskeletal 1 OS=Homo sapiens OX=9606 GN=KRT1 PE=1 SV=6" 4.37 3463.5 - 2.81E+06 - - - -1.068 - 2.838 0.566 - 935.2 1 2 0 -0.0016 12 0 0 0 0.00E+00 0.00E+00 - - - 5.9656 0.9999 221125_WJC_METTL3_EV_vs_WT_F03.21549.21549.3 0.00016 Dec-48 R.K[136.11]VESLQEEIAFLK.K "sp|P08670|VIME_HUMAN,tr|B0YJC5|B0YJC5_HUMAN,tr|B0YJC4|B0YJC4_HUMAN" 3 1540.8592 - 36367 21549 3 1540.856013 514.627 Vimentin OS=Homo sapiens OX=9606 GN=VIM PE=1 SV=4 4.79 3463.5 - 2.62E+06 - - - -2.0748 - 2.331 0.426 - 198.9 1 2 0 -0.0032 13 0 0 0 - - - - - 5.5832 1 221125_WJC_METTL3_EV_vs_WT_F03.21550.21550.2 2.78E-09 18/32 R.LQVTNVLSQPLTQATVK.L "sp|P04844|RPN2_HUMAN,tr|Q5JYR7|Q5JYR7_HUMAN,tr|Q5JYR4|Q5JYR4_HUMAN" 3 1839.0466 1.24 36368 21550 2 1839.043758 920.5306 Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit 2 OS=Homo sapiens OX=9606 GN=RPN2 PE=1 SV=3 8.75 3463.6 - 2.20E+06 - - - -1.5252 - 3.661 0.637 - 901.7 1 2 0 -0.0028 17 0 0 0 2.10E+07 1.69E+07 - - - 6.9355 0.9986 221125_WJC_METTL3_EV_vs_WT_F03.21551.21551.2 0.000195 22-Oct K.ELWFSDDPNVTK.T "sp|O95831|AIFM1_HUMAN,tr|A0A6Q8PFW2|A0A6Q8PFW2_HUMAN,tr|A0A6Q8PFA7|A0A6Q8PFA7_HUMAN,tr|A0A6Q8PHJ9|A0A6Q8PHJ9_HUMAN,tr|A0A6Q8PFS4|A0A6Q8PFS4_HUMAN,tr|A0A7I2PK44|A0A7I2PK44_HUMAN,tr|A0A6Q8PF87|A0A6Q8PF87_HUMAN,tr|A0A6Q8PG15|A0A6Q8PG15_HUMAN,tr|A0A6Q8PFE1|A0A6Q8PFE1_HUMAN,tr|A0A7I2RLJ8|A0A7I2RLJ8_HUMAN,tr|A0A6Q8PFQ8|A0A6Q8PFQ8_HUMAN,tr|A0A6Q8PHC0|A0A6Q8PHC0_HUMAN,tr|A0A6Q8PFM5|A0A6Q8PFM5_HUMAN" 13 1449.6776 1.09 36369 21551 2 1449.677859 725.8461 "Apoptosis-inducing factor 1, mitochondrial OS=Homo sapiens OX=9606 GN=AIFM1 PE=1 SV=1" 4.03 3463.7 - 1.95E+06 - - - 0.1718 - 1.467 0.278 - 160.6 1 2 0 0.0002 12 0 0 0 1.15E+07 1.06E+07 - - - 2.1025 0.9998 221125_WJC_METTL3_EV_vs_WT_F03.21553.21553.3 3.74E-05 Nov-44 K.SK[136.11]DWVFLNYTYK[136.11].R sp|Q9Y2H1|ST38L_HUMAN 1 1578.8053 2.84 36371 21553 3 1578.80334 527.2757 Serine\threonine-protein kinase 38-like OS=Homo sapiens OX=9606 GN=STK38L PE=1 SV=3 8.15 3463.9 - 1.79E+06 - - - -1.2604 - 2.56 0.459 - 150.7 1 2 1 -0.002 12 0 0 0 3.96E+07 1.39E+07 - - - 6.2624 1 221125_WJC_METTL3_EV_vs_WT_F03.21554.21554.3 5.44E-07 15/64 K.GTVGEPTYDAEFQHFLR.G "sp|Q14204|DYHC1_HUMAN,tr|A0A7P0T8N2|A0A7P0T8N2_HUMAN,tr|A0A7P0T9C4|A0A7P0T9C4_HUMAN,tr|A0A7P0TBJ7|A0A7P0TBJ7_HUMAN,tr|A0A2R8Y706|A0A2R8Y706_HUMAN,tr|A0A7P0T916|A0A7P0T916_HUMAN,tr|A0A7P0TB75|A0A7P0TB75_HUMAN,tr|A0A7P0TAF3|A0A7P0TAF3_HUMAN,tr|A0A7P0TAW9|A0A7P0TAW9_HUMAN,tr|A0A7P0TA13|A0A7P0TA13_HUMAN,tr|A0A7P0T7V5|A0A7P0T7V5_HUMAN,tr|A0A7P0T9R4|A0A7P0T9R4_HUMAN,tr|A0A2R8Y5T0|A0A2R8Y5T0_HUMAN" 13 1965.9221 1.42 36372 21554 3 1965.918616 656.3146 Cytoplasmic dynein 1 heavy chain 1 OS=Homo sapiens OX=9606 GN=DYNC1H1 PE=1 SV=5 4.65 3464 - 1.72E+06 - - - -1.7676 - 3.236 0.557 - 315.1 1 2 0 -0.0035 17 0 0 0 6.14E+06 4.32E+06 - - - 7.7158 0.9999 221125_WJC_METTL3_EV_vs_WT_F03.21555.21555.3 0.0151 14/40 K.SFEMVLDEIRK.A "sp|Q86XN7|PRSR1_HUMAN,tr|Q5JS36|Q5JS36_HUMAN" 2 1365.6962 1.88 36373 21555 3 1365.695 456.2394 Proline and serine-rich protein 1 OS=Homo sapiens OX=9606 GN=PROSER1 PE=1 SV=2 4.68 3464.1 - 1.20E+06 - - - -0.9058 - 2.078 0.405 - 212.1 1 2 0 -0.0012 11 0 0 0 2.84E+07 1.51E+07 - - - 5.1328 0.9999 221125_WJC_METTL3_EV_vs_WT_F03.21558.21558.3 5.19E-05 13/44 K.DAGTIAGLNVLR[166.11].L "sp|P11142|HSP7C_HUMAN,tr|E9PQQ4|E9PQQ4_HUMAN,tr|E9PKE3|E9PKE3_HUMAN,tr|E9PN89|E9PN89_HUMAN,tr|E9PLF4|E9PLF4_HUMAN,tr|E9PI65|E9PI65_HUMAN,tr|E9PK54|E9PK54_HUMAN,tr|E9PQK7|E9PQK7_HUMAN" 8 1208.6753 0.11 36376 21558 3 1208.673611 403.899 Heat shock cognate 71 kDa protein OS=Homo sapiens OX=9606 GN=HSPA8 PE=1 SV=1 5.84 3464.4 - 997570 - - - -1.361 - 2.425 0.42 - 191.2 1 2 0 -0.0016 12 0 0 0 1.11E+06 9.86E+06 - - - 5.6775 1 221125_WJC_METTL3_EV_vs_WT_F03.21562.21562.3 1.62E-08 14/48 R.K[136.11]VESLQEEIAFLK[136.11].K "sp|P08670|VIME_HUMAN,tr|B0YJC5|B0YJC5_HUMAN,tr|B0YJC4|B0YJC4_HUMAN" 3 1548.8734 2.03 36379 21562 3 1548.870945 517.2984 Vimentin OS=Homo sapiens OX=9606 GN=VIM PE=1 SV=4 4.79 3464.9 - 1.06E+08 - - - -1.5915 - 3.154 0.563 - 477.6 1 2 0 -0.0025 13 0 0 0 1.25E+09 6.18E+08 - - - 7.9306 0.9999 221125_WJC_METTL3_EV_vs_WT_F03.21565.21565.3 0.00065 Dec-44 R.SEEELLVIFNK[136.11]K[136.11].L sp|Q9NX58|LYAR_HUMAN 1 1463.8206 0.62 36382 21565 3 1463.820217 488.9475 Cell growth-regulating nucleolar protein OS=Homo sapiens OX=9606 GN=LYAR PE=1 SV=2 4.78 3465.1 - 2.83E+06 - - - -0.2931 - 2.253 0.443 - 230.1 1 2 0 -0.0004 12 0 0 0 1.12E+07 1.82E+07 - - - 5.7304 0.9994 221125_WJC_METTL3_EV_vs_WT_F03.21567.21567.3 7.73E-05 Oct-40 K.SFEMVLDEIR[166.11]K[136.11].A "sp|Q86XN7|PRSR1_HUMAN,tr|Q5JS36|Q5JS36_HUMAN" 2 1383.7187 2.03 36384 21567 3 1383.717835 462.2468 Proline and serine-rich protein 1 OS=Homo sapiens OX=9606 GN=PROSER1 PE=1 SV=2 4.68 3465.2 - 2.19E+06 - - - -0.6302 - 1.984 0.291 - 92.9 1 2 0 -0.0009 11 0 0 0 3.08E+07 1.52E+07 - - - 3.7304 0.9998 221125_WJC_METTL3_EV_vs_WT_F03.21569.21569.3 6.23E-05 Dec-56 R.VR[166.11]DVLDFYNVPIQDR[166.11].S sp|Q8N5N7|RM50_HUMAN 1 1867.9695 1.44 36386 21569 3 1867.968737 623.6638 "39S ribosomal protein L50, mitochondrial OS=Homo sapiens OX=9606 GN=MRPL50 PE=1 SV=2" 4.43 3465.4 - 1.81E+06 - - - -0.4283 - 2.544 0.44 - 168.1 1 2 1 -0.0008 15 0 0 0 6.98E+07 4.86E+07 - - - 5.8818 0.9995 221125_WJC_METTL3_EV_vs_WT_F03.21575.21575.2 2.71E-05 13/26 K.SGGGIVEPIPLNIK[136.11].T "sp|Q8N954|GPT11_HUMAN,tr|A0A6I8PRS5|A0A6I8PRS5_HUMAN" 2 1400.8119 1.65 36392 21575 2 1400.808974 701.4132 G patch domain-containing protein 11 OS=Homo sapiens OX=9606 GN=GPATCH11 PE=1 SV=4 5.72 3466.1 - 597288 - - - -2.0645 - 1.902 0.454 - 480.5 1 2 0 -0.0029 14 0 0 0 9.38E+06 5.67E+06 - - - 4.0067 1 221125_WJC_METTL3_EV_vs_WT_F03.21580.21580.3 3.99E-08 14/44 K.WELLQQVDTSTR.T sp|P04264|K2C1_HUMAN 1 1474.7416 2169.19 36395 21580 3 1474.741049 492.5878 "Keratin, type II cytoskeletal 1 OS=Homo sapiens OX=9606 GN=KRT1 PE=1 SV=6" 4.37 3466.5 - 6.03E+06 - - - -0.3784 - 2.6 0.435 - 355.2 1 2 0 -0.0006 12 0 0 0 1.17E+09 5.41E+05 - - - 6.0382 1 221125_WJC_METTL3_EV_vs_WT_F03.21581.21581.2 1.09E-07 14/26 T.TDNANILLQIDNAR.L "sp|P13645|K1C10_HUMAN,tr|A0A1B0GVI3|A0A1B0GVI3_HUMAN" 2 1569.8111 999 36396 21581 2 1569.809813 785.9128 "Keratin, type I cytoskeletal 10 OS=Homo sapiens OX=9606 GN=KRT10 PE=1 SV=6" 4.21 3466.7 - 2.34E+06 - - - -0.8097 - 3.255 0.581 - 669.8 1 1 0 -0.0013 14 0 0 0 1.87E+07 0.00E+00 - - - 6.2935 1 221125_WJC_METTL3_EV_vs_WT_F03.21585.21585.3 2.89E-08 23/80 K.LLSDTVASDPGVLQEQLATTK.Q "sp|Q9UPN3|MACF1_HUMAN,tr|H3BQK9|H3BQK9_HUMAN,tr|A0A7P0MQR8|A0A7P0MQR8_HUMAN,tr|H0Y390|H0Y390_HUMAN,tr|H3BPE1|H3BPE1_HUMAN,tr|A0A590UJG2|A0A590UJG2_HUMAN" 6 2185.1478 3.02 36400 21585 3 2185.148898 729.3899 "Microtubule-actin cross-linking factor 1, isoforms 1\2\3\5 OS=Homo sapiens OX=9606 GN=MACF1 PE=1 SV=4" 4.03 3467.1 - 1.66E+06 - - - 0.5052 - 3.685 0.554 - 527.7 1 2 0 0.0011 21 0 0 0 9.45E+06 3.13E+06 - - - 7.8432 1 221125_WJC_METTL3_EV_vs_WT_F03.21586.21586.2 0.0271 17/28 R.SQNVMAAASIANIVK[136.11].S "sp|P17987|TCPA_HUMAN,tr|F5GZI8|F5GZI8_HUMAN,tr|E7ERF2|E7ERF2_HUMAN,tr|F5GYL4|F5GYL4_HUMAN" 4 1523.8221 0.36 36401 21586 2 1523.820366 762.9183 T-complex protein 1 subunit alpha OS=Homo sapiens OX=9606 GN=TCP1 PE=1 SV=1 8.47 3467.2 - 1.61E+06 - - - -1.1465 - 3.458 0.58 - 787.3 1 2 0 -0.0017 15 0 0 0 3.79E+08 1.04E+09 - - - 6.3746 1 221125_WJC_METTL3_EV_vs_WT_F03.21587.21587.3 1.77E-05 16/56 R.IPFNQALVFSNLHSR[166.11].A "sp|Q9UHI6|DDX20_HUMAN,tr|A0A7P0T8G7|A0A7P0T8G7_HUMAN,tr|A0A7P0TB94|A0A7P0TB94_HUMAN,tr|A0A7P0T9T8|A0A7P0T9T8_HUMAN" 4 1751.9347 1.73 36402 21587 3 1751.935939 584.9855 Probable ATP-dependent RNA helicase DDX20 OS=Homo sapiens OX=9606 GN=DDX20 PE=1 SV=2 9.76 3467.4 - 1.00E+06 - - - 0.7306 - 3.401 0.461 - 428.7 1 2 0 0.0013 15 0 0 0 9.98E+06 5.76E+06 - - - 6.8734 0.999 221125_WJC_METTL3_EV_vs_WT_F03.21589.21589.3 4.65E-05 Nov-48 R.NGIDVDK[136.11]WDYFAR[166.11].D "sp|Q9Y3Z3|SAMH1_HUMAN,tr|A0A2R8YD90|A0A2R8YD90_HUMAN,tr|A0A2R8YCS7|A0A2R8YCS7_HUMAN" 3 1615.775 0.2 36404 21589 3 1615.772097 539.5989 Deoxynucleoside triphosphate triphosphohydrolase SAMHD1 OS=Homo sapiens OX=9606 GN=SAMHD1 PE=1 SV=2 4.43 3467.6 - 901226 - - - -1.7818 - 2.285 0.369 - 105.6 1 2 1 -0.0029 13 0 0 0 1.73E+06 8.59E+06 - - - 4.8937 1 221125_WJC_METTL3_EV_vs_WT_F03.21595.21595.2 3.48E-06 13/22 K.SKDWVFLNYTYK.R sp|Q9Y2H1|ST38L_HUMAN 1 1562.7769 2.82 36409 21595 2 1562.776514 782.3957 Serine\threonine-protein kinase 38-like OS=Homo sapiens OX=9606 GN=STK38L PE=1 SV=3 8.15 3468.3 - 599858 - - - -0.2662 - 2.762 0.55 - 488.2 1 2 1 -0.0004 12 0 0 0 5.65E+06 2.00E+06 - - - 5.7763 0.9999 221125_WJC_METTL3_EV_vs_WT_F03.21597.21597.3 1.04E-06 17/56 R.VRDVLDFYNVPIQDR.S sp|Q8N5N7|RM50_HUMAN 1 1847.953 1.44 36411 21597 3 1847.951812 616.9916 "39S ribosomal protein L50, mitochondrial OS=Homo sapiens OX=9606 GN=MRPL50 PE=1 SV=2" 4.43 3468.4 - 4.63E+06 - - - -0.6413 - 2.971 0.562 - 352.3 1 2 1 -0.0012 15 0 0 0 6.98E+07 4.86E+07 - - - 7.6468 1 221125_WJC_METTL3_EV_vs_WT_F03.21598.21598.3 0.0217 16/52 R.TLFVSGLPVDIKPR.E sp|Q6ZRY4|RBPS2_HUMAN 1 1540.8977 1.56 36412 21598 3 1540.900112 514.6398 RNA-binding protein with multiple splicing 2 OS=Homo sapiens OX=9606 GN=RBPMS2 PE=1 SV=1 8.41 3468.4 - 2.78E+06 - - - 1.5562 - 2.86 0.512 - 311.6 1 2 0 0.0024 14 0 0 0 5.79E+07 3.72E+07 - - - 7.0402 0.9999 221125_WJC_METTL3_EV_vs_WT_F03.21600.21600.2 0.0014 14/28 R.SQNVMAAASIANIVK.S "sp|P17987|TCPA_HUMAN,tr|F5GZI8|F5GZI8_HUMAN,tr|E7ERF2|E7ERF2_HUMAN,tr|F5GYL4|F5GYL4_HUMAN" 4 1515.8079 0.36 36414 21600 2 1515.805549 758.9112 T-complex protein 1 subunit alpha OS=Homo sapiens OX=9606 GN=TCP1 PE=1 SV=1 8.47 3468.6 - 2.20E+06 - - - -1.5596 - 3.072 0.488 - 567 1 2 0 -0.0024 15 0 0 0 3.79E+08 1.04E+09 - - - 5.4039 0.9999 221125_WJC_METTL3_EV_vs_WT_F03.21601.21601.3 7.75E-07 16/68 K.VLFMSSEENKDFPAVGLK.T sp|Q9NS00|C1GLT_HUMAN 1 2010.0132 1 36415 21601 3 2010.010396 671.0117 Glycoprotein-N-acetylgalactosamine 3-beta-galactosyltransferase 1 OS=Homo sapiens OX=9606 GN=C1GALT1 PE=1 SV=1 4.68 3468.7 - 1.32E+06 - - - -1.402 - 2.964 0.542 - 156.1 1 2 1 -0.0028 18 0 0 0 2.57E+07 2.57E+07 - - - 7.2876 1 221125_WJC_METTL3_EV_vs_WT_F03.21603.21603.2 5.47E-08 17/28 K.ITNLTQQLEQASIVK.K sp|P15924|DESP_HUMAN 1 1684.936 63.6 36417 21603 2 1684.934816 843.4753 Desmoplakin OS=Homo sapiens OX=9606 GN=DSP PE=1 SV=3 6 3468.9 - 1.21E+06 - - - -0.673 - 3.335 0.564 - 1082.6 1 2 0 -0.0011 15 0 0 0 1.71E+08 2.69E+06 - - - 6.1676 0.9963 221125_WJC_METTL3_EV_vs_WT_F03.21604.21604.3 0.000223 Dec-44 K.IAFTEWIEPPK[136.11]R[166.11].E sp|O60264|SMCA5_HUMAN 1 1503.8205 0.86 36418 21604 3 1503.812912 502.2808 SWI\SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A member 5 OS=Homo sapiens OX=9606 GN=SMARCA5 PE=1 SV=1 6.14 3469 - 813987 - - - -5.0259 - 2.101 0.346 - 186.9 1 2 0 -0.0076 12 0 0 0 1.32E+07 1.53E+07 - - - 4.4533 0.9797 221125_WJC_METTL3_EV_vs_WT_F03.21605.21605.2 2.32E-05 14/30 K.AIEEGIPAFTC[160.03]EEYVK[136.11].S "sp|Q9Y2L1|RRP44_HUMAN,tr|F2Z2C0|F2Z2C0_HUMAN,tr|G3V1J5|G3V1J5_HUMAN" 3 1862.8852 1.2 36419 21605 2 1863.88372 932.4499 Exosome complex exonuclease RRP44 OS=Homo sapiens OX=9606 GN=DIS3 PE=1 SV=2 4.09 3469.2 - 649438 - - - 536.025 - 2.425 0.481 - 407 1 2 0 0.9986 16 0 0 0 3.72E+07 3.10E+07 - - - 4.458 0.9765 221125_WJC_METTL3_EV_vs_WT_F03.21606.21606.2 0.0681 Sep-32 K.NSDVLQSPLDSAARDEL.- sp|Q8NBJ5|GT251_HUMAN 1 1828.8803 -1 36420 21606 2 1828.874318 915.4474 Procollagen galactosyltransferase 1 OS=Homo sapiens OX=9606 GN=COLGALT1 PE=1 SV=1 3.84 3469.3 - 408720 - - - -3.2632 - 1.975 0.346 - 189.3 1 2 1 -0.006 17 0 0 0 0.00E+00 0.00E+00 - - - 3.2679 1 221125_WJC_METTL3_EV_vs_WT_F03.21611.21611.3 1.92E-08 16/52 R.TLFVSGLPVDIK[136.11]PR[166.11].E sp|Q6ZRY4|RBPS2_HUMAN 1 1558.9202 1.56 36423 21611 3 1558.919254 520.6473 RNA-binding protein with multiple splicing 2 OS=Homo sapiens OX=9606 GN=RBPMS2 PE=1 SV=1 8.41 3469.8 - 3.55E+06 - - - -0.5966 - 2.582 0.569 - 283.2 1 2 0 -0.0009 14 0 0 0 5.79E+07 3.72E+07 - - - 7.4044 0.9999 221125_WJC_METTL3_EV_vs_WT_F03.21612.21612.3 5.43E-06 15/44 R.ETLAQLQQEFQR.A sp|O15212|PFD6_HUMAN 1 1489.7525 3.98 36424 21612 3 1489.749114 497.5914 Prefoldin subunit 6 OS=Homo sapiens OX=9606 GN=PFDN6 PE=1 SV=1 4.53 3469.9 - 3.53E+06 - - - -2.2769 - 2.672 0.484 - 467.2 1 2 0 -0.0034 12 0 0 0 1.76E+08 4.41E+07 - - - 6.6594 1 221125_WJC_METTL3_EV_vs_WT_F03.21620.21620.2 6.56E-09 14/22 R.ETLAQLQQEFQR.A sp|O15212|PFD6_HUMAN 1 1489.7525 2.66 36430 21620 2 1489.747628 745.8835 Prefoldin subunit 6 OS=Homo sapiens OX=9606 GN=PFDN6 PE=1 SV=1 4.53 3470.8 - 1.02E+07 - - - -3.2744 - 2.718 0.605 - 1059.2 1 2 0 -0.0049 12 0 0 0 2.74E+08 1.03E+08 - - - 6.1389 0.9679 221125_WJC_METTL3_EV_vs_WT_F03.21628.21628.3 0.00038 15/56 R.DVAPQAPVHFLVIPK.K sp|Q9BX68|HINT2_HUMAN 1 1629.9243 1.84 36438 21628 3 1629.917611 544.3154 Adenosine 5'-monophosphoramidase HINT2 OS=Homo sapiens OX=9606 GN=HINT2 PE=1 SV=1 6.74 3471.6 - 1.61E+06 - - - -4.0812 - 2.488 0.131 - 164.3 1 2 0 -0.0067 15 0 0 0 1.99E+07 1.08E+07 - - - 2.3771 1 221125_WJC_METTL3_EV_vs_WT_F03.21640.21640.3 1.23E-11 22/56 K.ITNLTQQLEQASIVK.K sp|P15924|DESP_HUMAN 1 1684.936 17.4 36446 21640 3 1684.935294 562.6526 Desmoplakin OS=Homo sapiens OX=9606 GN=DSP PE=1 SV=3 6 3472.9 - 4.47E+06 - - - -0.3893 - 3.812 0.584 - 866 1 2 0 -0.0007 15 0 0 0 5.99E+07 3.44E+06 - - - 8.5426 1 221125_WJC_METTL3_EV_vs_WT_F03.21642.21642.3 0.000817 22/72 R.LATYGITVAELTGDHQLC[160.03]K.E "sp|O75643|U520_HUMAN,tr|A0A494C1A5|A0A494C1A5_HUMAN" 2 2089.0514 1.92 36448 21642 3 2089.048188 697.3577 U5 small nuclear ribonucleoprotein 200 kDa helicase OS=Homo sapiens OX=9606 GN=SNRNP200 PE=1 SV=2 5.32 3473.1 - 2.84E+06 - - - -1.5332 - 3.95 0.514 - 628.6 1 2 0 -0.0032 19 0 0 0 5.14E+07 2.67E+07 - - - 7.6447 1 221125_WJC_METTL3_EV_vs_WT_F03.21643.21643.3 5.89E-08 19/72 R.LATYGITVAELTGDHQLC[160.03]K[136.11].E "sp|O75643|U520_HUMAN,tr|A0A494C1A5|A0A494C1A5_HUMAN" 2 2097.0656 1.97 36449 21643 3 2097.06262 700.0291 U5 small nuclear ribonucleoprotein 200 kDa helicase OS=Homo sapiens OX=9606 GN=SNRNP200 PE=1 SV=2 5.32 3473.2 - 1.67E+06 - - - -1.4167 - 3.597 0.481 - 450.1 1 2 0 -0.003 19 0 0 0 5.26E+07 2.66E+07 - - - 7.0468 0.9996 221125_WJC_METTL3_EV_vs_WT_F03.21646.21646.3 1.10E-05 16/56 R.SQNVMAAASIANIVK.S "sp|P17987|TCPA_HUMAN,tr|F5GZI8|F5GZI8_HUMAN,tr|E7ERF2|E7ERF2_HUMAN,tr|F5GYL4|F5GYL4_HUMAN" 4 1515.8079 0.41 36450 21646 3 1515.800443 506.2766 T-complex protein 1 subunit alpha OS=Homo sapiens OX=9606 GN=TCP1 PE=1 SV=1 8.47 3473.6 - 3.26E+06 - - - -4.9281 - 2.965 0.473 - 327.1 1 2 0 -0.0075 15 0 0 0 5.36E+07 1.31E+08 - - - 6.6475 0.9999 221125_WJC_METTL3_EV_vs_WT_F03.21647.21647.3 1.16E-09 15/68 K.SVVDYNAYAGVWSQDK[136.11]WK[136.11].G "sp|Q7Z739|YTHD3_HUMAN,tr|A0A087X0Q1|A0A087X0Q1_HUMAN,tr|A0A024R7W5|A0A024R7W5_HUMAN,tr|A0A087WY31|A0A087WY31_HUMAN" 4 2131.0346 0.33 36451 21647 3 2131.033464 711.3521 YTH domain-containing family protein 3 OS=Homo sapiens OX=9606 GN=YTHDF3 PE=1 SV=1 5.68 3473.7 - 2.80E+06 - - - -0.512 - 2.986 0.556 - 153 1 2 1 -0.0011 18 0 0 0 1.53E+07 4.63E+07 - - - 7.4626 0.9996 221125_WJC_METTL3_EV_vs_WT_F03.21649.21649.2 0.00107 16-Oct K.LLQDFFNGK[136.11].E "sp|P54652|HSP72_HUMAN,sp|P11142|HSP7C_HUMAN,sp|P17066|HSP76_HUMAN,tr|E9PNE6|E9PNE6_HUMAN,tr|A8K7Q2|A8K7Q2_HUMAN,tr|E9PKE3|E9PKE3_HUMAN,tr|E9PN89|E9PN89_HUMAN" 7 1088.5746 0.15 36453 21649 2 1088.573712 545.2946 Heat shock-related 70 kDa protein 2 OS=Homo sapiens OX=9606 GN=HSPA2 PE=1 SV=1 5.84 3473.9 - 2.80E+06 - - - -0.8112 - 1.788 0.344 - 243.5 1 2 0 -0.0009 9 0 0 0 2.20E+07 1.50E+08 - - - 3.2627 0.9997 221125_WJC_METTL3_EV_vs_WT_F03.21652.21652.2 0.000272 20-Oct R.DITVLDLGC[160.03]GK[136.11].G "sp|O43148|MCES_HUMAN,tr|K7EP06|K7EP06_HUMAN" 2 1197.6155 1.21 36456 21652 2 1197.612926 599.815 mRNA cap guanine-N7 methyltransferase OS=Homo sapiens OX=9606 GN=RNMT PE=1 SV=1 4.21 3474.2 - 1.46E+06 - - - -2.1276 - 2.189 0.48 - 274.9 1 2 0 -0.0025 11 0 0 0 2.72E+07 2.25E+07 - - - 4.7049 0.9997 221125_WJC_METTL3_EV_vs_WT_F03.21655.21655.3 3.25E-07 16/44 K.QAYVDK[136.11]LEELMK[136.11].L "sp|Q92598|HS105_HUMAN,tr|A0A0A0MSM0|A0A0A0MSM0_HUMAN" 2 1481.7771 0.1 36457 21655 3 1481.772737 494.933 Heat shock protein 105 kDa OS=Homo sapiens OX=9606 GN=HSPH1 PE=1 SV=1 4.68 3474.6 - 4.12E+06 - - - -2.9222 - 2.777 0.521 - 292.8 1 2 1 -0.0043 12 0 0 0 1.90E+07 1.88E+08 - - - 7.1785 1 221125_WJC_METTL3_EV_vs_WT_F03.21656.21656.2 3.66E-08 17/26 K.MEEEILLLEDQNSK[136.11].F sp|P35580|MYH10_HUMAN 1 1697.8273 5.48 36458 21656 2 1697.824415 849.9209 Myosin-10 OS=Homo sapiens OX=9606 GN=MYH10 PE=1 SV=3 3.91 3474.7 - 1.09E+06 - - - -1.7098 - 3.471 0.648 - 1420.2 1 2 0 -0.0029 14 0 0 0 8.29E+07 1.51E+07 - - - 6.9491 1 221125_WJC_METTL3_EV_vs_WT_F03.21659.21659.3 1.11E-07 17/52 K.VSHLLGINVTDFTR[166.11].G sp|P35579|MYH9_HUMAN 1 1580.855 0.88 36461 21659 3 1580.851767 527.9589 Myosin-9 OS=Homo sapiens OX=9606 GN=MYH9 PE=1 SV=4 6.71 3475.1 - 2.37E+06 - - - -2.0521 - 3.054 0.488 - 491.1 1 2 0 -0.0032 14 0 0 0 3.13E+08 3.56E+08 - - - 6.9468 0.9998 221125_WJC_METTL3_EV_vs_WT_F03.21666.21666.2 1.77E-07 16/30 K.AIEEGIPAFTC[160.03]EEYVK.S "sp|Q9Y2L1|RRP44_HUMAN,tr|F2Z2C0|F2Z2C0_HUMAN,tr|G3V1J5|G3V1J5_HUMAN" 3 1854.871 1.25 36466 21666 2 1854.86777 928.4428 Exosome complex exonuclease RRP44 OS=Homo sapiens OX=9606 GN=DIS3 PE=1 SV=2 4.09 3475.9 - 1.66E+06 - - - -1.7236 - 2.863 0.522 - 561.8 1 2 0 -0.0032 16 0 0 0 3.72E+07 2.98E+07 - - - 5.4816 0.9725 221125_WJC_METTL3_EV_vs_WT_F03.21667.21667.2 0.00162 15/26 Q.LDGIHLLDPDVVAR[166.11].F sp|Q86U44|MTA70_HUMAN 1 1541.8441 0.1 36467 21667 2 1541.839182 771.9293 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 4.41 3476 - 1.51E+06 - - - -3.1975 - 2.874 0.508 - 554.2 1 1 0 -0.0049 14 0 0 0 1.71E+07 1.63E+08 - - - 5.4408 0.9997 221125_WJC_METTL3_EV_vs_WT_F03.21672.21672.2 1.68E-06 13/26 R.AGGIETIANEFSDR[166.11].C "sp|Q92598|HS105_HUMAN,tr|R4GN69|R4GN69_HUMAN" 2 1488.7084 0.37 36470 21672 2 1488.704583 745.3615 Heat shock protein 105 kDa OS=Homo sapiens OX=9606 GN=HSPH1 PE=1 SV=1 4.14 3476.6 - 7.76E+06 - - - -2.5687 - 2.679 0.555 - 622.4 1 2 0 -0.0038 14 0 0 0 1.92E+08 5.26E+08 - - - 5.612 1 221125_WJC_METTL3_EV_vs_WT_F03.21673.21673.2 1.32E-09 16/24 K.TVDNFVALATGEK[136.11].G "sp|P23284|PPIB_HUMAN,tr|A0A7P0Z497|A0A7P0Z497_HUMAN,tr|A0A7P0T7U3|A0A7P0T7U3_HUMAN" 3 1371.7125 0.6 36471 21673 2 1371.709795 686.8635 Peptidyl-prolyl cis-trans isomerase B OS=Homo sapiens OX=9606 GN=PPIB PE=1 SV=2 4.37 3476.7 - 3.19E+06 - - - -2.0055 - 3.102 0.61 - 556.2 1 2 0 -0.0028 13 0 0 0 7.36E+07 1.24E+08 - - - 6.451 0.9999 221125_WJC_METTL3_EV_vs_WT_F03.21675.21675.3 6.54E-06 17/68 K.SVVDYNAYAGVWSQDKWK.G "sp|Q7Z739|YTHD3_HUMAN,tr|A0A087X0Q1|A0A087X0Q1_HUMAN,tr|A0A024R7W5|A0A024R7W5_HUMAN,tr|A0A087WY31|A0A087WY31_HUMAN" 4 2115.0062 0.33 36473 21675 3 2115.008747 706.0093 YTH domain-containing family protein 3 OS=Homo sapiens OX=9606 GN=YTHDF3 PE=1 SV=1 5.68 3477 - 1.99E+06 - - - 1.2255 - 3.395 0.519 - 198.4 1 2 1 0.0026 18 0 0 0 1.53E+07 4.58E+07 - - - 7.3693 0.9664 221125_WJC_METTL3_EV_vs_WT_F03.21676.21676.2 0.000267 28-Dec R.LDVGNFSWGSEC[160.03]C[160.03]TR[166.11].K sp|P62241|RS8_HUMAN 1 1796.7486 0.19 36474 21676 2 1797.74563 899.3816 40S ribosomal protein S8 OS=Homo sapiens OX=9606 GN=RPS8 PE=1 SV=2 4.37 3477.1 - 1.69E+06 - - - 554.9224 - 1.917 0.595 - 224.4 1 2 0 0.9971 15 0 0 0 3.09E+06 1.60E+07 - - - 4.7225 0.9997 221125_WJC_METTL3_EV_vs_WT_F03.21678.21678.2 9.11E-05 16-Aug K.LLQDFFNGK.E "sp|P54652|HSP72_HUMAN,sp|P11142|HSP7C_HUMAN,sp|P17066|HSP76_HUMAN,tr|E9PNE6|E9PNE6_HUMAN,tr|A8K7Q2|A8K7Q2_HUMAN,tr|E9PKE3|E9PKE3_HUMAN,tr|E9PN89|E9PN89_HUMAN" 7 1080.5604 0.15 36476 21678 2 1080.558552 541.2875 Heat shock-related 70 kDa protein 2 OS=Homo sapiens OX=9606 GN=HSPA2 PE=1 SV=1 5.84 3477.4 - 1.44E+06 - - - -1.7056 - 1.596 0.512 - 138.5 1 2 0 -0.0018 9 0 0 0 2.20E+07 1.50E+08 - - - 4.1746 0.9611 221125_WJC_METTL3_EV_vs_WT_F03.21680.21680.2 4.60E-08 30-Dec A.YAGYPSQFVPGLDPSK.S sp|Q9H7S9|ZN703_HUMAN 1 1724.841 3.26 36478 21680 2 1724.834645 863.4278 Zinc finger protein 703 OS=Homo sapiens OX=9606 GN=ZNF703 PE=1 SV=1 5.83 3477.6 - 869157 - - - -3.6769 - 2.119 0.614 - 301.2 1 1 0 -0.0063 16 0 0 0 1.87E+07 5.75E+06 - - - 5.4202 1 221125_WJC_METTL3_EV_vs_WT_F03.21685.21685.2 9.97E-08 15/24 K.TVDNFVALATGEK.G "sp|P23284|PPIB_HUMAN,tr|A0A7P0Z497|A0A7P0Z497_HUMAN,tr|A0A7P0T7U3|A0A7P0T7U3_HUMAN" 3 1363.6983 0.63 36481 21685 2 1363.69593 682.8564 Peptidyl-prolyl cis-trans isomerase B OS=Homo sapiens OX=9606 GN=PPIB PE=1 SV=2 4.37 3478.3 - 2.43E+06 - - - -1.7717 - 2.756 0.636 - 549.4 1 2 0 -0.0024 13 0 0 0 7.75E+07 1.24E+08 - - - 6.3396 0.9997 221125_WJC_METTL3_EV_vs_WT_F03.21686.21686.3 1.45E-11 20/72 K.FEPIHGNFLLTGAYDNTAK.L sp|O43172|PRP4_HUMAN 1 2107.0375 3.19 36482 21686 3 2107.024697 703.3531 U4\U6 small nuclear ribonucleoprotein Prp4 OS=Homo sapiens OX=9606 GN=PRPF4 PE=1 SV=2 5.32 3478.3 - 2.21E+06 - - - -6.0549 - 3.493 0.605 - 666.7 1 2 0 -0.0128 19 0 0 0 6.30E+08 1.97E+08 - - - 8.3545 1 221125_WJC_METTL3_EV_vs_WT_F03.21687.21687.3 4.87E-12 21/68 K.VMVELLGSYTEDNASQAR[166.11].V "sp|Q7L2H7|EIF3M_HUMAN,tr|J3KNJ2|J3KNJ2_HUMAN,tr|E9PRY0|E9PRY0_HUMAN,tr|H0YCQ8|H0YCQ8_HUMAN" 4 1991.9498 2.2 36483 21687 3 1991.945739 664.9905 Eukaryotic translation initiation factor 3 subunit M OS=Homo sapiens OX=9606 GN=EIF3M PE=1 SV=1 4.14 3478.5 - 2.06E+06 - - - -2.0267 - 3.367 0.621 - 417 1 2 0 -0.004 18 0 0 0 3.49E+07 1.59E+07 - - - 8.4855 0.9991 221125_WJC_METTL3_EV_vs_WT_F03.21689.21689.2 0.0178 20-Nov R.DITVLDLGC[160.03]GK.G "sp|O43148|MCES_HUMAN,tr|K7EP06|K7EP06_HUMAN" 2 1189.6013 1.21 36485 21689 2 1189.597568 595.8079 mRNA cap guanine-N7 methyltransferase OS=Homo sapiens OX=9606 GN=RNMT PE=1 SV=1 4.21 3478.8 - 1.94E+06 - - - -3.1153 - 2.198 0.416 - 299.8 1 2 0 -0.0037 11 0 0 0 2.72E+07 2.25E+07 - - - 4.2429 1 221125_WJC_METTL3_EV_vs_WT_F03.21690.21690.2 1.08E-09 19/38 K.GNPQGFNQGLDC[160.03]DVIVAEVR[166.11].S sp|Q86U44|MTA70_HUMAN 1 2197.0461 0.03 36486 21690 2 2198.036138 1099.5303 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 4.03 3478.9 - 1.86E+06 - - - 450.6059 - 3.577 0.652 - 874.6 1 2 0 0.99 20 0 0 0 4.38E+08 1.36E+10 - - - 6.6793 1 221125_WJC_METTL3_EV_vs_WT_F03.21692.21692.2 1.59E-09 15/28 K.YSEVFEAINITNNEK.V "sp|P68400|CSK21_HUMAN,sp|Q8NEV1|CSK23_HUMAN,tr|A0A2R8YCK2|A0A2R8YCK2_HUMAN,tr|A0A2R8YFU2|A0A2R8YFU2_HUMAN,tr|V9GYA2|V9GYA2_HUMAN,tr|A0A2R8YEW1|A0A2R8YEW1_HUMAN,tr|A0A2R8Y4D6|A0A2R8Y4D6_HUMAN,tr|A0A2R8YD58|A0A2R8YD58_HUMAN,tr|A0A2R8YF43|A0A2R8YF43_HUMAN,tr|A0A2R8Y5A0|A0A2R8Y5A0_HUMAN,tr|A0A2R8YDY7|A0A2R8YDY7_HUMAN,tr|A0A2R8YF47|A0A2R8YF47_HUMAN,tr|A0A2R8Y4H0|A0A2R8Y4H0_HUMAN,tr|A0A2R8Y7T1|A0A2R8Y7T1_HUMAN,tr|A0A2R8YDP2|A0A2R8YDP2_HUMAN,tr|A0A2R8Y797|A0A2R8Y797_HUMAN,tr|A0A2R8YEL7|A0A2R8YEL7_HUMAN,tr|V9GY80|V9GY80_HUMAN,tr|E7EU96|E7EU96_HUMAN,tr|A0A2R8Y3W6|A0A2R8Y3W6_HUMAN" 20 1769.8472 1.33 36488 21692 2 1769.843625 885.9309 Casein kinase II subunit alpha OS=Homo sapiens OX=9606 GN=CSNK2A1 PE=1 SV=1 4.25 3479.1 - 1.44E+06 - - - -2.0171 - 2.869 0.618 - 923.4 1 2 0 -0.0036 15 0 0 0 1.69E+07 1.27E+07 - - - 6.1956 0.9998 221125_WJC_METTL3_EV_vs_WT_F03.21693.21693.2 3.56E-07 16/28 R.AEEYEFLTPVEEAPK.G "sp|P52565|GDIR1_HUMAN,tr|J3KRE2|J3KRE2_HUMAN,tr|J3QQX2|J3QQX2_HUMAN,tr|J3KTF8|J3KTF8_HUMAN" 4 1750.8301 0.02 36489 21693 2 1750.83285 876.4224 Rho GDP-dissociation inhibitor 1 OS=Homo sapiens OX=9606 GN=ARHGDIA PE=1 SV=3 3.98 3479.3 - 1.35E+06 - - - 1.5433 - 2.653 0.526 - 957.4 1 2 0 0.0027 15 0 0 0 2.61E+07 1.41E+09 - - - 5.324 0.9975 221125_WJC_METTL3_EV_vs_WT_F03.21695.21695.2 4.90E-05 14/26 K.GYAIELPEDIEENR[166.11].A "sp|Q9Y2W6|TDRKH_HUMAN,tr|F6TB26|F6TB26_HUMAN,tr|Q5SZR4|Q5SZR4_HUMAN" 3 1656.7871 1.08 36491 21695 2 1656.778189 829.4008 Tudor and KH domain-containing protein OS=Homo sapiens OX=9606 GN=TDRKH PE=1 SV=2 3.91 3479.5 - 1.29E+06 - - - -5.3489 - 2.743 0.494 - 544.9 1 2 0 -0.0089 14 0 0 0 3.15E+07 2.93E+07 - - - 5.2191 1 221125_WJC_METTL3_EV_vs_WT_F03.21696.21696.2 4.03E-08 15/28 K.YSEVFEAINITNNEK[136.11].V "sp|P68400|CSK21_HUMAN,sp|Q8NEV1|CSK23_HUMAN,tr|A0A2R8YCK2|A0A2R8YCK2_HUMAN,tr|A0A2R8YFU2|A0A2R8YFU2_HUMAN,tr|V9GYA2|V9GYA2_HUMAN,tr|A0A2R8YEW1|A0A2R8YEW1_HUMAN,tr|A0A2R8Y4D6|A0A2R8Y4D6_HUMAN,tr|A0A2R8YD58|A0A2R8YD58_HUMAN,tr|A0A2R8YF43|A0A2R8YF43_HUMAN,tr|A0A2R8Y5A0|A0A2R8Y5A0_HUMAN,tr|A0A2R8YDY7|A0A2R8YDY7_HUMAN,tr|A0A2R8YF47|A0A2R8YF47_HUMAN,tr|A0A2R8Y4H0|A0A2R8Y4H0_HUMAN,tr|A0A2R8Y7T1|A0A2R8Y7T1_HUMAN,tr|A0A2R8YDP2|A0A2R8YDP2_HUMAN,tr|A0A2R8Y797|A0A2R8Y797_HUMAN,tr|A0A2R8YEL7|A0A2R8YEL7_HUMAN,tr|V9GY80|V9GY80_HUMAN,tr|E7EU96|E7EU96_HUMAN,tr|A0A2R8Y3W6|A0A2R8Y3W6_HUMAN" 20 1777.8614 1.33 36492 21696 2 1777.858255 889.938 Casein kinase II subunit alpha OS=Homo sapiens OX=9606 GN=CSNK2A1 PE=1 SV=1 4.25 3479.7 - 1.27E+06 - - - -1.7662 - 2.921 0.591 - 827 1 2 0 -0.0031 15 0 0 0 1.69E+07 1.27E+07 - - - 6.0405 1 221125_WJC_METTL3_EV_vs_WT_F03.21699.21699.2 1.32E-11 17/34 K.VMVELLGSYTEDNASQAR.V "sp|Q7L2H7|EIF3M_HUMAN,tr|J3KNJ2|J3KNJ2_HUMAN,tr|E9PRY0|E9PRY0_HUMAN,tr|H0YCQ8|H0YCQ8_HUMAN" 4 1981.9415 1.46 36495 21699 2 1981.943158 991.978 Eukaryotic translation initiation factor 3 subunit M OS=Homo sapiens OX=9606 GN=EIF3M PE=1 SV=1 4.14 3480.1 - 989169 - - - 0.8335 - 3.326 0.694 - 598.2 1 2 0 0.0017 18 0 0 0 6.90E+06 4.73E+06 - - - 7.121 1 221125_WJC_METTL3_EV_vs_WT_F03.21702.21702.2 9.68E-08 13/28 G.AAGTVFTTVEDLGSK.L "tr|A0A087X215|A0A087X215_HUMAN,tr|A0A7P0TB04|A0A7P0TB04_HUMAN,tr|A0A2R8YDZ0|A0A2R8YDZ0_HUMAN" 3 1494.7566 1.05 36496 21702 2 1494.751854 748.3856 Basigin OS=Homo sapiens OX=9606 GN=BSG PE=1 SV=1 4.37 3480.4 - 1.06E+07 - - - -3.1677 - 3.155 0.647 - 557.5 1 1 0 -0.0047 15 0 0 0 4.38E+08 4.18E+08 - - - 6.6431 0.9931 221125_WJC_METTL3_EV_vs_WT_F03.21704.21704.3 3.74E-07 15/40 K.WNLDELPKFEK.N "sp|P17844|DDX5_HUMAN,tr|J3QR02|J3QR02_HUMAN,tr|X6RLV5|X6RLV5_HUMAN,tr|A0A7I2V507|A0A7I2V507_HUMAN,tr|J3KTA4|J3KTA4_HUMAN,tr|J3KTQ4|J3KTQ4_HUMAN,tr|A0A7I2V2S0|A0A7I2V2S0_HUMAN,tr|J3QRQ7|J3QRQ7_HUMAN" 8 1417.7242 1.55 36498 21704 3 1417.715279 473.582 Probable ATP-dependent RNA helicase DDX5 OS=Homo sapiens OX=9606 GN=DDX5 PE=1 SV=1 4.68 3480.6 - 3.06E+06 - - - -6.2685 - 2.231 0.483 - 322.9 1 2 1 -0.0089 11 0 0 0 1.53E+08 9.89E+07 - - - 6.2021 0.9998 221125_WJC_METTL3_EV_vs_WT_F03.21705.21705.3 1.56E-05 Dec-52 R.AGGIETIANEFSDR[166.11].C "sp|Q92598|HS105_HUMAN,tr|R4GN69|R4GN69_HUMAN" 2 1488.7084 0.06 36499 21705 3 1488.702903 497.2434 Heat shock protein 105 kDa OS=Homo sapiens OX=9606 GN=HSPH1 PE=1 SV=1 4.14 3480.6 - 2.76E+06 - - - -3.6972 - 2.583 0.459 - 240.3 1 2 0 -0.0055 14 0 0 0 1.91E+06 3.06E+07 - - - 6.1777 1 221125_WJC_METTL3_EV_vs_WT_F03.21707.21707.3 1.71E-10 27/88 R.ISGETIFVTAPHEATAGIIGVNR[166.11].K "sp|Q00610|CLH1_HUMAN,tr|A0A087WVQ6|A0A087WVQ6_HUMAN" 2 2362.252 1.09 36501 21707 3 2362.241073 788.4246 Clathrin heavy chain 1 OS=Homo sapiens OX=9606 GN=CLTC PE=1 SV=5 5.4 3480.9 - 1.48E+06 - - - -4.6384 - 4.814 0.639 - 797.3 1 2 0 -0.011 23 0 0 0 7.36E+07 6.78E+07 - - - 9.3479 0.9859 221125_WJC_METTL3_EV_vs_WT_F03.21712.21712.2 0.0701 30-Nov R.MIASQVVDINLAAEPK.V "sp|P0DMR1|HNRC4_HUMAN,sp|O60812|HNRC1_HUMAN,sp|B7ZW38|HNRC3_HUMAN,tr|A0A0G2JPF8|A0A0G2JPF8_HUMAN" 4 1697.9022 1.74 36504 21712 2 1697.89558 849.9584 Heterogeneous nuclear ribonucleoprotein C-like 4 OS=Homo sapiens OX=9606 GN=HNRNPCL4 PE=3 SV=1 4.37 3481.5 - 2.70E+06 - - - -3.9031 - 1.546 0.249 - 187.4 1 2 0 -0.0066 16 0 0 0 2.29E+09 1.32E+09 - - - 1.9492 0.9999 221125_WJC_METTL3_EV_vs_WT_F03.21714.21714.3 0.0026 17/60 R.MIASQVVDINLAAEPK.V "sp|P0DMR1|HNRC4_HUMAN,sp|O60812|HNRC1_HUMAN,sp|B7ZW38|HNRC3_HUMAN,tr|A0A0G2JPF8|A0A0G2JPF8_HUMAN" 4 1697.9022 1.73 36506 21714 3 1697.898626 566.9747 Heterogeneous nuclear ribonucleoprotein C-like 4 OS=Homo sapiens OX=9606 GN=HNRNPCL4 PE=3 SV=1 4.37 3481.8 - 1.86E+06 - - - -2.1091 - 2.845 0.407 - 283.8 1 2 0 -0.0036 16 0 0 0 7.53E+08 4.35E+08 - - - 5.7594 0.998 221125_WJC_METTL3_EV_vs_WT_F03.21718.21718.2 0.138 15/26 K.VSHLLGINVTDFTR[166.11].G sp|P35579|MYH9_HUMAN 1 1580.855 1.03 36508 21718 2 1580.847063 791.4348 Myosin-9 OS=Homo sapiens OX=9606 GN=MYH9 PE=1 SV=4 6.71 3482.3 - 2.70E+06 - - - -5.0277 - 2.674 0.492 - 735.2 1 2 0 -0.0079 14 0 0 0 3.18E+07 3.09E+07 - - - 5.1406 1 221125_WJC_METTL3_EV_vs_WT_F03.21719.21719.2 2.48E-05 17/28 K.GLATSLQNDLQEVPK.L sp|Q8N0X7|SPART_HUMAN 1 1611.8468 1.21 36509 21719 2 1611.83781 806.9307 Spartin OS=Homo sapiens OX=9606 GN=SPART PE=1 SV=1 4.37 3482.4 - 1.67E+06 - - - -5.5781 - 3.043 0.584 - 597.2 1 2 0 -0.009 15 0 0 0 2.73E+08 2.26E+08 - - - 6.0876 0.9847 221125_WJC_METTL3_EV_vs_WT_F03.21720.21720.2 0.118 30-Sep R.MIASQVVDINLAAEPK[136.11].V "sp|P0DMR1|HNRC4_HUMAN,sp|O60812|HNRC1_HUMAN,sp|B7ZW38|HNRC3_HUMAN,tr|A0A0G2JPF8|A0A0G2JPF8_HUMAN" 4 1705.9164 1.74 36510 21720 2 1705.909783 853.9655 Heterogeneous nuclear ribonucleoprotein C-like 4 OS=Homo sapiens OX=9606 GN=HNRNPCL4 PE=3 SV=1 4.37 3482.5 - 4.80E+06 - - - -3.883 - 1.657 0.215 - 120.5 1 2 0 -0.0066 16 0 0 0 2.29E+09 1.32E+09 - - - 1.8685 1 221125_WJC_METTL3_EV_vs_WT_F03.21721.21721.2 8.84E-24 23/38 K.NYGSYSTQASAAAATAELLK.K sp|O14828|SCAM3_HUMAN 1 2015.98 1.59 36511 21721 2 2015.973414 1008.9973 Secretory carrier-associated membrane protein 3 OS=Homo sapiens OX=9606 GN=SCAMP3 PE=1 SV=3 6 3482.7 - 1.67E+06 - - - -3.2669 - 4.625 0.73 - 1817.6 1 2 0 -0.0066 20 0 0 0 4.12E+07 2.59E+07 - - - 8.1959 0.9999 221125_WJC_METTL3_EV_vs_WT_F03.21722.21722.3 2.36E-09 14/76 K.NYGSYSTQASAAAATAELLK.K sp|O14828|SCAM3_HUMAN 1 2015.98 1.69 36512 21722 3 2015.971595 673.0006 Secretory carrier-associated membrane protein 3 OS=Homo sapiens OX=9606 GN=SCAMP3 PE=1 SV=3 6 3482.8 - 1.53E+06 - - - -4.1692 - 2.928 0.577 - 165.8 1 2 0 -0.0084 20 0 0 0 2.81E+07 1.66E+07 - - - 7.577 1 221125_WJC_METTL3_EV_vs_WT_F03.21723.21723.2 4.28E-12 18/38 K.NYGSYSTQASAAAATAELLK[136.11].K sp|O14828|SCAM3_HUMAN 1 2023.9942 1.59 36513 21723 2 2023.987088 1013.0044 Secretory carrier-associated membrane protein 3 OS=Homo sapiens OX=9606 GN=SCAMP3 PE=1 SV=3 6 3482.9 - 1.20E+06 - - - -3.5138 - 3.92 0.713 - 771.8 1 2 0 -0.0071 20 0 0 0 4.12E+07 2.59E+07 - - - 7.6636 0.9967 221125_WJC_METTL3_EV_vs_WT_F03.21726.21726.3 0.000174 13/44 K.QAYVDKLEELMK.L "sp|Q92598|HS105_HUMAN,tr|A0A0A0MSM0|A0A0A0MSM0_HUMAN" 2 1465.7487 0.1 36515 21726 3 1465.743489 489.5902 Heat shock protein 105 kDa OS=Homo sapiens OX=9606 GN=HSPH1 PE=1 SV=1 4.68 3483.3 - 965195 - - - -3.5327 - 2.401 0.356 - 183.4 1 2 1 -0.0052 12 0 0 0 1.90E+07 1.88E+08 - - - 4.9354 0.9994 221125_WJC_METTL3_EV_vs_WT_F03.21730.21730.2 4.45E-08 16/28 K.GLATSLQNDLQEVPK[136.11].L sp|Q8N0X7|SPART_HUMAN 1 1619.861 1.21 36518 21730 2 1619.855526 810.9378 Spartin OS=Homo sapiens OX=9606 GN=SPART PE=1 SV=1 4.37 3483.7 - 2.81E+06 - - - -3.3799 - 2.759 0.501 - 626.2 1 2 0 -0.0055 15 0 0 0 2.73E+08 2.26E+08 - - - 5.2348 1 221125_WJC_METTL3_EV_vs_WT_F03.21731.21731.2 6.08E-11 19/38 K.GNPQGFNQGLDC[160.03]DVIVAEVR.S sp|Q86U44|MTA70_HUMAN 1 2187.0379 0.03 36519 21731 2 2188.033234 1094.5262 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 4.03 3483.8 - 2.76E+06 - - - 455.1215 - 3.363 0.713 - 870.1 1 2 0 0.9954 20 0 0 0 4.37E+08 1.36E+10 - - - 6.9765 1 221125_WJC_METTL3_EV_vs_WT_F03.21732.21732.3 0.00511 18/80 R.TAPTALGITLSSSPTSTPELR.V "sp|O75970|MPDZ_HUMAN,tr|F5H1U9|F5H1U9_HUMAN" 2 2099.111 999 36520 21732 3 2099.111314 700.7109 Multiple PDZ domain protein OS=Homo sapiens OX=9606 GN=MPDZ PE=1 SV=2 5.66 3483.9 - 1.26E+06 - - - 0.1429 - 3.541 0.398 - 280.3 1 2 0 0.0003 21 0 0 0 1.15E+07 0.00E+00 - - - 6.0086 0.9998 221125_WJC_METTL3_EV_vs_WT_F03.21737.21737.3 4.68E-05 13/60 R.MIASQVVDINLAAEPK[136.11].V "sp|P0DMR1|HNRC4_HUMAN,sp|O60812|HNRC1_HUMAN,sp|B7ZW38|HNRC3_HUMAN,tr|A0A0G2JPF8|A0A0G2JPF8_HUMAN" 4 1705.9164 1.72 36523 21737 3 1705.912969 569.6461 Heterogeneous nuclear ribonucleoprotein C-like 4 OS=Homo sapiens OX=9606 GN=HNRNPCL4 PE=3 SV=1 4.37 3484.5 - 6.48E+06 - - - -2.0153 - 2.438 0.403 - 149.6 1 2 0 -0.0034 16 0 0 0 7.51E+08 4.36E+08 - - - 5.3187 1 221125_WJC_METTL3_EV_vs_WT_F03.21738.21738.3 1.97E-11 19/72 K.SVRPNDEVTAVLAVQTELK.E sp|P12273|PIP_HUMAN 1 2068.1164 90.05 36524 21738 3 2068.114447 690.3794 Prolactin-inducible protein OS=Homo sapiens OX=9606 GN=PIP PE=1 SV=1 4.68 3484.5 - 4.49E+06 - - - -0.9608 - 3.85 0.618 - 598.7 1 2 0 -0.002 19 0 0 0 2.32E+08 2.58E+06 - - - 8.7415 0.8253 221125_WJC_METTL3_EV_vs_WT_F03.21740.21740.3 0.00188 Dec-36 R.SIFDHIKLPQ.A "sp|Q9NYF8|BCLF1_HUMAN,tr|E9PKI6|E9PKI6_HUMAN,tr|A0A1W2PQ43|A0A1W2PQ43_HUMAN,tr|E9PK91|E9PK91_HUMAN,tr|E9PJA7|E9PJA7_HUMAN,tr|E9PK09|E9PK09_HUMAN,tr|E9PQN2|E9PQN2_HUMAN" 7 1196.6554 2.34 36526 21740 3 1196.652606 399.8924 Bcl-2-associated transcription factor 1 OS=Homo sapiens OX=9606 GN=BCLAF1 PE=1 SV=2 6.46 3484.7 - 1.47E+06 - - - -2.3006 - 1.823 0.385 - 172.6 1 1 1 -0.0028 10 0 0 0 2.23E+07 9.53E+06 - - - 4.5853 1 221125_WJC_METTL3_EV_vs_WT_F03.21744.21744.3 5.34E-07 18/76 K.FGVVLDEIKPSSAPELQAVR.M "sp|O14579|COPE_HUMAN,tr|M0QXB4|M0QXB4_HUMAN,tr|M0R061|M0R061_HUMAN" 3 2154.1685 1.26 36528 21744 3 2154.16795 719.0634 Coatomer subunit epsilon OS=Homo sapiens OX=9606 GN=COPE PE=1 SV=3 4.68 3485.3 - 4.83E+06 - - - -0.2409 - 3.099 0.562 - 283.5 1 2 0 -0.0005 20 0 0 0 1.11E+08 8.82E+07 - - - 7.5496 1 221125_WJC_METTL3_EV_vs_WT_F03.21746.21746.3 2.30E-09 16/76 K.GNPQGFNQGLDC[160.03]DVIVAEVR.S sp|Q86U44|MTA70_HUMAN 1 2187.0379 0.03 36530 21746 3 2188.032609 730.0199 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 4.03 3485.4 - 2.24E+07 - - - 454.8357 - 2.944 0.683 - 297.3 1 2 0 0.9947 20 0 0 0 1.27E+09 4.05E+10 - - - 8.4988 0.9679 221125_WJC_METTL3_EV_vs_WT_F03.21748.21748.3 0.000146 14/64 L.GNQLDGIHLLDPDVVAR[166.11].F sp|Q86U44|MTA70_HUMAN 1 1840.9671 0.001 36532 21748 3 1840.961321 614.663 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 4.41 3485.5 - 3.38E+06 - - - -3.1288 - 2.381 0.424 - 174.9 1 1 0 -0.0058 17 0 0 0 0.00E+00 1.49E+08 - - - 5.4572 0.9998 221125_WJC_METTL3_EV_vs_WT_F03.21750.21750.3 4.17E-09 20/68 K.QALEEAATADLDITEINK[136.11].L sp|Q53HL2|BOREA_HUMAN 1 1951.983 2.93 36534 21750 3 1951.973939 651.6683 Borealin OS=Homo sapiens OX=9606 GN=CDCA8 PE=1 SV=2 3.83 3485.8 - 1.76E+06 - - - -4.625 - 3.29 0.515 - 630.7 1 2 0 -0.009 18 0 0 0 4.75E+07 1.62E+07 - - - 7.2447 1 221125_WJC_METTL3_EV_vs_WT_F03.21753.21753.3 2.64E-08 27/76 K.FGVVLDEIK[136.11]PSSAPELQAVR[166.11].M "sp|O14579|COPE_HUMAN,tr|M0QXB4|M0QXB4_HUMAN,tr|M0R061|M0R061_HUMAN" 3 2172.1909 1.26 36535 21753 3 2172.188108 725.0709 Coatomer subunit epsilon OS=Homo sapiens OX=9606 GN=COPE PE=1 SV=3 4.68 3486.1 - 7.97E+06 - - - -1.3033 - 4.45 0.642 - 780.6 1 2 0 -0.0028 20 0 0 0 1.11E+08 8.82E+07 - - - 9.3187 1 221125_WJC_METTL3_EV_vs_WT_F03.21757.21757.2 6.44E-14 22/38 K.FTASAGIQVVGDDLTVTNPK.R "sp|P06733|ENOA_HUMAN,tr|A0A2R8Y6G6|A0A2R8Y6G6_HUMAN" 2 2032.0477 2.49 36539 21757 2 2032.041638 1017.0311 Alpha-enolase OS=Homo sapiens OX=9606 GN=ENO1 PE=1 SV=2 4.21 3486.5 - 2.42E+06 - - - -2.9763 - 4.21 0.659 - 1420.3 1 2 0 -0.006 20 0 0 0 1.83E+08 7.32E+07 - - - 7.4405 1 221125_WJC_METTL3_EV_vs_WT_F03.21759.21759.2 3.26E-13 18/38 K.FTASAGIQVVGDDLTVTNPK[136.11].R "sp|P06733|ENOA_HUMAN,tr|A0A2R8Y6G6|A0A2R8Y6G6_HUMAN" 2 2040.0619 2.48 36541 21759 2 2040.048574 1021.0382 Alpha-enolase OS=Homo sapiens OX=9606 GN=ENO1 PE=1 SV=2 4.21 3486.8 - 1.64E+06 - - - -6.5253 - 3.828 0.473 - 976.2 1 2 0 -0.0133 20 0 0 0 1.81E+08 7.32E+07 - - - 5.8306 1 221125_WJC_METTL3_EV_vs_WT_F03.21762.21762.2 1.18E-09 17/28 R.PMNIQLVTSQIDAQR[166.11].R "sp|Q86V81|THOC4_HUMAN,tr|E9PB61|E9PB61_HUMAN" 2 1722.8962 0.68 36542 21762 2 1722.890778 862.4554 THO complex subunit 4 OS=Homo sapiens OX=9606 GN=ALYREF PE=1 SV=3 6.27 3487.1 - 4.70E+06 - - - -3.161 - 3.216 0.65 - 940.2 1 1 0 -0.0054 15 0 0 0 4.62E+08 6.83E+08 - - - 6.7121 0.9979 221125_WJC_METTL3_EV_vs_WT_F03.21763.21763.3 5.61E-07 19/56 R.PMNIQLVTSQIDAQR.R "sp|Q86V81|THOC4_HUMAN,tr|E9PB61|E9PB61_HUMAN" 2 1712.888 0.72 36543 21763 3 1712.885385 571.9699 THO complex subunit 4 OS=Homo sapiens OX=9606 GN=ALYREF PE=1 SV=3 6.27 3487.2 - 6.52E+06 - - - -1.4998 - 3.515 0.506 - 768 1 1 0 -0.0026 15 0 0 0 6.57E+08 9.07E+08 - - - 7.4608 0.9998 221125_WJC_METTL3_EV_vs_WT_F03.21764.21764.2 1.49E-06 14/22 R.TLNNQFASFIDK.V sp|Q8N1N4|K2C78_HUMAN 1 1396.6987 999 36544 21764 2 1396.696362 699.3566 "Keratin, type II cytoskeletal 78 OS=Homo sapiens OX=9606 GN=KRT78 PE=1 SV=2" 5.5 3487.3 - 3.77E+06 - - - -1.6596 - 2.556 0.5 - 512.2 1 2 0 -0.0023 12 0 0 0 2.62E+08 0.00E+00 - - - 5.2025 1 221125_WJC_METTL3_EV_vs_WT_F03.21766.21766.2 8.25E-10 15/30 Q.GFNQGLDC[160.03]DVIVAEVR[166.11].S sp|Q86U44|MTA70_HUMAN 1 1800.8704 0.001 36546 21766 2 1800.855509 901.4425 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 4.03 3487.5 - 3.15E+06 - - - -8.271 - 2.942 0.651 - 811.9 1 1 0 -0.0149 16 0 0 0 0.00E+00 5.51E+07 - - - 6.4976 1 221125_WJC_METTL3_EV_vs_WT_F03.21767.21767.2 4.13E-10 25/36 K.FEPIHGNFLLTGAYDNTAK.L sp|O43172|PRP4_HUMAN 1 2107.0375 16.52 36547 21767 2 2107.025865 1054.526 U4\U6 small nuclear ribonucleoprotein Prp4 OS=Homo sapiens OX=9606 GN=PRPF4 PE=1 SV=2 5.32 3487.7 - 3.03E+06 - - - -5.5006 - 4.999 0.69 - 2412.5 1 2 0 -0.0116 19 0 0 0 3.34E+07 2.02E+06 - - - 8.0901 1 221125_WJC_METTL3_EV_vs_WT_F03.21768.21768.2 8.55E-08 22-Oct K.ENFPNFLSAC[160.03]DK.K "sp|Q86SG5|S1A7A_HUMAN,sp|P31151|S10A7_HUMAN" 2 1440.6344 243.63 36548 21768 2 1440.625685 721.3245 Protein S100-A7A OS=Homo sapiens OX=9606 GN=S100A7A PE=1 SV=3 4.37 3487.8 - 2.96E+06 - - - -6.0251 - 2.482 0.582 - 362.1 1 2 0 -0.0087 12 0 0 0 3.82E+08 1.57E+06 - - - 5.7288 1 221125_WJC_METTL3_EV_vs_WT_F03.21772.21772.2 6.07E-07 17/28 R.PMNIQLVTSQIDAQR.R "sp|Q86V81|THOC4_HUMAN,tr|E9PB61|E9PB61_HUMAN" 2 1712.888 0.68 36550 21772 2 1712.883447 857.4513 THO complex subunit 4 OS=Homo sapiens OX=9606 GN=ALYREF PE=1 SV=3 6.27 3488.2 - 8.98E+06 - - - -2.6312 - 3.626 0.654 - 1012.4 1 1 0 -0.0045 15 0 0 0 4.62E+08 6.83E+08 - - - 7.037 0.9972 221125_WJC_METTL3_EV_vs_WT_F03.21773.21773.4 2.71E-06 13/114 K.GNPQGFNQGLDC[160.03]DVIVAEVR[166.11].S sp|Q86U44|MTA70_HUMAN 1 2197.0461 0.001 36551 21773 4 2198.04292 550.2688 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 4.03 3488.3 - 6.23E+06 - - - 453.6928 - 2.465 0.553 - 105.6 1 2 0 0.9968 20 0 0 0 0.00E+00 1.05E+08 - - - 4.0648 1 221125_WJC_METTL3_EV_vs_WT_F03.21774.21774.2 4.19E-05 17/30 K.IFVGGLSVNTTVEDVK.Q "sp|O43347|MSI1H_HUMAN,tr|H0YHB7|H0YHB7_HUMAN" 2 1676.8985 3.16 36552 21774 2 1676.893902 839.4565 RNA-binding protein Musashi homolog 1 OS=Homo sapiens OX=9606 GN=MSI1 PE=1 SV=1 4.37 3488.4 - 2.44E+06 - - - -2.7432 - 3.071 0.539 - 742.6 1 2 0 -0.0046 16 0 0 0 3.32E+07 1.05E+07 - - - 5.7791 0.9621 221125_WJC_METTL3_EV_vs_WT_F03.21775.21775.2 0.081 20-Oct K.STSESFIQHIV.S "sp|Q9NYF8|BCLF1_HUMAN,tr|E9PKI6|E9PKI6_HUMAN,tr|A0A1W2PQ43|A0A1W2PQ43_HUMAN,tr|E9PK91|E9PK91_HUMAN,tr|E9PJA7|E9PJA7_HUMAN,tr|E9PK09|E9PK09_HUMAN,tr|E9PQN2|E9PQN2_HUMAN" 7 1246.6194 - 36553 21775 2 1246.617909 624.317 Bcl-2-associated transcription factor 1 OS=Homo sapiens OX=9606 GN=BCLAF1 PE=1 SV=2 5.22 3488.5 - 2.11E+06 - - - -1.1696 - 1.964 0.29 - 329.8 1 1 0 -0.0015 11 0 0 0 - - - - - 3.0085 0.9998 221125_WJC_METTL3_EV_vs_WT_F03.21779.21779.2 1.88 15/24 R.SLFSSIGEVESAK.L "sp|Q15717|ELAV1_HUMAN,tr|M0QZR9|M0QZR9_HUMAN" 2 1352.6824 1.14 36555 21779 2 1352.680209 677.3485 ELAV-like protein 1 OS=Homo sapiens OX=9606 GN=ELAVL1 PE=1 SV=2 4.53 3489 - 1.22E+07 - - - -1.5909 - 2.793 0.47 - 648.9 1 2 0 -0.0022 13 0 0 0 4.71E+08 4.13E+08 - - - 5.1479 0.9944 221125_WJC_METTL3_EV_vs_WT_F03.21780.21780.3 7.55E-06 17/56 R.PMNIQLVTSQIDAQR[166.11].R "sp|Q86V81|THOC4_HUMAN,tr|E9PB61|E9PB61_HUMAN" 2 1722.8962 0.72 36556 21780 3 1722.891865 575.306 THO complex subunit 4 OS=Homo sapiens OX=9606 GN=ALYREF PE=1 SV=3 6.27 3489 - 2.44E+07 - - - -2.53 - 3.497 0.469 - 638.3 1 1 0 -0.0044 15 0 0 0 6.57E+08 9.07E+08 - - - 7.0344 1 221125_WJC_METTL3_EV_vs_WT_F03.21782.21782.3 2.16E-07 22/48 K.NILFVITK[136.11]PDVYK[136.11].S "sp|E9PAV3|NACAM_HUMAN,sp|Q9BZK3|NACP4_HUMAN,sp|Q13765|NACA_HUMAN,tr|A0A7I2V473|A0A7I2V473_HUMAN,tr|F8VZJ2|F8VZJ2_HUMAN,tr|F8VNW4|F8VNW4_HUMAN,tr|A0A7I2V2K5|A0A7I2V2K5_HUMAN,tr|F8W0W4|F8W0W4_HUMAN,tr|H0YHX9|H0YHX9_HUMAN,tr|F8VZ58|F8VZ58_HUMAN" 10 1564.92 0.23 36558 21782 3 1564.918604 522.6473 "Nascent polypeptide-associated complex subunit alpha, muscle-specific form OS=Homo sapiens OX=9606 GN=NACA PE=1 SV=1" 8.5 3489.2 - 3.32E+06 - - - -0.8703 - 3.171 0.493 - 608 1 2 0 -0.0014 13 0 0 0 1.84E+07 7.86E+07 - - - 7.165 0.9999 221125_WJC_METTL3_EV_vs_WT_F03.21785.21785.3 6.32E-06 14/48 R.FVDKLFEAVEEGR.S sp|O43395|PRPF3_HUMAN 1 1537.7777 1.88 36559 21785 3 1537.774575 513.5998 U4\U6 small nuclear ribonucleoprotein Prp3 OS=Homo sapiens OX=9606 GN=PRPF3 PE=1 SV=2 4.41 3489.6 - 1.04E+07 - - - -2.0055 - 2.654 0.589 - 195.5 1 2 1 -0.0031 13 0 0 0 2.74E+08 1.46E+08 - - - 7.7523 0.9998 221125_WJC_METTL3_EV_vs_WT_F03.21787.21787.2 4.74E-05 24-Dec R.SLFSSIGEVESAK[136.11].L "sp|Q15717|ELAV1_HUMAN,tr|M0QZR9|M0QZR9_HUMAN" 2 1360.6966 1.14 36561 21787 2 1360.698682 681.3556 ELAV-like protein 1 OS=Homo sapiens OX=9606 GN=ELAVL1 PE=1 SV=2 4.53 3489.7 - 1.35E+07 - - - 1.5588 - 2.462 0.547 - 392 1 2 0 0.0021 13 0 0 0 4.71E+08 4.15E+08 - - - 5.3929 0.9999 221125_WJC_METTL3_EV_vs_WT_F03.21790.21790.3 2.51E-07 16/48 R.FVDK[136.11]LFEAVEEGR[166.11].S sp|O43395|PRPF3_HUMAN 1 1555.8001 1.87 36562 21790 3 1555.797572 519.6073 U4\U6 small nuclear ribonucleoprotein Prp3 OS=Homo sapiens OX=9606 GN=PRPF3 PE=1 SV=2 4.41 3490.1 - 7.38E+06 - - - -1.6435 - 2.686 0.597 - 263.4 1 2 1 -0.0026 13 0 0 0 2.74E+08 1.47E+08 - - - 7.8741 1 221125_WJC_METTL3_EV_vs_WT_F03.21801.21801.2 2.20E-12 14/24 K.QNC[160.03]ELFEQLGEYK.F "sp|P02768|ALBU_HUMAN,tr|A0A087WWT3|A0A087WWT3_HUMAN,tr|B7WNR0|B7WNR0_HUMAN,tr|H0YA55|H0YA55_HUMAN,tr|A0A0C4DGB6|A0A0C4DGB6_HUMAN,tr|D6RHD5|D6RHD5_HUMAN,tr|C9JKR2|C9JKR2_HUMAN" 7 1656.7454 999 36568 21801 2 1656.74275 829.38 Albumin OS=Homo sapiens OX=9606 GN=ALB PE=1 SV=2 4.25 3491.5 - 4.47E+06 - - - -1.5826 - 2.967 0.665 - 822.2 1 2 0 -0.0026 13 0 0 0 1.36E+08 0.00E+00 - - - 6.7431 1 221125_WJC_METTL3_EV_vs_WT_F03.21806.21806.3 1.45E-11 24/80 R.VIISAPSADAPMFVMGVNHEK.Y "sp|P04406|G3P_HUMAN,tr|E7EUT5|E7EUT5_HUMAN" 2 2212.102 1.03 36570 21806 3 2212.097509 738.3746 Glyceraldehyde-3-phosphate dehydrogenase OS=Homo sapiens OX=9606 GN=GAPDH PE=1 SV=3 5.32 3492.1 - 1.16E+08 - - - -2.051 - 3.613 0.665 - 554.3 1 2 0 -0.0045 21 0 0 0 6.03E+09 5.86E+09 - - - 9.0325 0.9796 221125_WJC_METTL3_EV_vs_WT_F03.21811.21811.2 4.31E-11 20/36 K.AIQDGTIVLMGTYDDGATK[136.11].L sp|Q92520|FAM3C_HUMAN 1 1975.9652 2.78 36573 21811 2 1975.952085 988.9899 Protein FAM3C OS=Homo sapiens OX=9606 GN=FAM3C PE=1 SV=1 3.93 3492.7 - 2.97E+06 - - - -6.6413 - 3.549 0.171 - 742.7 1 2 0 -0.0131 19 0 0 0 4.55E+07 1.64E+07 - - - 3.414 1 221125_WJC_METTL3_EV_vs_WT_F03.21815.21815.3 3.14E-10 18/76 K.FTASAGIQVVGDDLTVTNPK.R "sp|P06733|ENOA_HUMAN,tr|A0A2R8Y6G6|A0A2R8Y6G6_HUMAN" 2 2032.0477 2.09 36576 21815 3 2032.046012 678.3565 Alpha-enolase OS=Homo sapiens OX=9606 GN=ENO1 PE=1 SV=2 4.21 3493.1 - 5.30E+06 - - - -0.8238 - 3.434 0.575 - 465 1 2 0 -0.0017 20 0 0 0 2.60E+08 1.24E+08 - - - 7.9433 1 221125_WJC_METTL3_EV_vs_WT_F03.21816.21816.2 6.73E-15 19/40 R.VIISAPSADAPMFVMGVNHEK.Y "sp|P04406|G3P_HUMAN,tr|E7EUT5|E7EUT5_HUMAN" 2 2212.102 2.13 36577 21816 2 2212.101426 1107.0583 Glyceraldehyde-3-phosphate dehydrogenase OS=Homo sapiens OX=9606 GN=GAPDH PE=1 SV=3 5.32 3493.1 - 4.99E+06 - - - -0.2803 - 3.66 0.734 - 889 1 2 0 -0.0006 21 0 0 0 1.53E+08 7.20E+07 - - - 7.652 1 221125_WJC_METTL3_EV_vs_WT_F03.21817.21817.3 1.89E-10 21/68 K.ALVSHNGSLINVGSLLQR.A "sp|Q8N163|CCAR2_HUMAN,tr|H0YB24|H0YB24_HUMAN,tr|G3V119|G3V119_HUMAN" 3 1877.0483 1.23 36578 21817 3 1877.050208 626.69 Cell cycle and apoptosis regulator protein 2 OS=Homo sapiens OX=9606 GN=CCAR2 PE=1 SV=2 9.8 3493.2 - 2.14E+06 - - - 1.0192 - 4.034 0.556 - 519.6 1 2 0 0.0019 18 0 0 0 1.92E+07 1.56E+07 - - - 8.2114 0.998 221125_WJC_METTL3_EV_vs_WT_F03.21818.21818.3 2.06E-08 19/64 T.YSDNQPGVLIQVYEGER[166.11].A "sp|P0DMV8|HS71A_HUMAN,sp|P34931|HS71L_HUMAN,sp|P11142|HSP7C_HUMAN,sp|P0DMV9|HS71B_HUMAN,tr|E9PNE6|E9PNE6_HUMAN,tr|A8K7Q2|A8K7Q2_HUMAN,tr|E9PKE3|E9PKE3_HUMAN,tr|E9PS65|E9PS65_HUMAN,tr|Q53FA3|Q53FA3_HUMAN,tr|V9GZ37|V9GZ37_HUMAN,tr|A0A0G2JIW1|A0A0G2JIW1_HUMAN" 11 1975.9515 0.29 36579 21818 3 1975.9537 659.6578 Heat shock 70 kDa protein 1A OS=Homo sapiens OX=9606 GN=HSPA1A PE=1 SV=1 4.14 3493.3 - 1.86E+06 - - - 1.1184 - 3.167 0.535 - 471.1 1 1 0 0.0022 17 0 0 0 3.01E+07 1.05E+08 - - - 7.4164 0.9914 221125_WJC_METTL3_EV_vs_WT_F03.21825.21825.2 1.02E-05 15/28 N.QLDGIHLLDPDVVAR[166.11].F sp|Q86U44|MTA70_HUMAN 1 1669.9027 0.02 36582 21825 2 1669.900252 835.9586 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 4.41 3494.1 - 7.09E+06 - - - -1.46 - 2.813 0.508 - 418.8 1 1 0 -0.0024 15 0 0 0 5.77E+06 2.38E+08 - - - 5.3351 1 221125_WJC_METTL3_EV_vs_WT_F03.21827.21827.3 8.34E-12 23/76 K.PVTTPEEIAQVATISANGDK[136.11].E "sp|P10809|CH60_HUMAN,tr|A0A7I2V599|A0A7I2V599_HUMAN,tr|E7EXB4|E7EXB4_HUMAN,tr|A0A7I2YQ71|A0A7I2YQ71_HUMAN,tr|E7ESH4|E7ESH4_HUMAN,tr|A0A7I2V5M1|A0A7I2V5M1_HUMAN,tr|A0A7I2V5K3|A0A7I2V5K3_HUMAN,tr|A0A7I2V369|A0A7I2V369_HUMAN" 8 2048.0517 1.53 36584 21827 3 2048.044851 683.6912 "60 kDa heat shock protein, mitochondrial OS=Homo sapiens OX=9606 GN=HSPD1 PE=1 SV=2" 4.14 3494.2 - 5.21E+06 - - - -3.3515 - 4.254 0.633 - 908.9 1 1 0 -0.0069 20 0 0 0 6.01E+08 3.93E+08 - - - 9.108 0.9999 221125_WJC_METTL3_EV_vs_WT_F03.21832.21832.4 1.24E-06 21/120 R.VIISAPSADAPMFVMGVNHEK.Y "sp|P04406|G3P_HUMAN,tr|E7EUT5|E7EUT5_HUMAN" 2 2212.102 1.06 36587 21832 4 2212.096593 554.0328 Glyceraldehyde-3-phosphate dehydrogenase OS=Homo sapiens OX=9606 GN=GAPDH PE=1 SV=3 5.32 3494.9 - 5.29E+06 - - - -2.4651 - 3.362 0.525 - 264.7 1 2 0 -0.0055 21 0 0 0 8.61E+07 8.14E+07 - - - 4.195 1 221125_WJC_METTL3_EV_vs_WT_F03.21839.21839.2 1.02E-11 16/40 R.VIISAPSADAPMFVMGVNHEK[136.11].Y "sp|P04406|G3P_HUMAN,tr|E7EUT5|E7EUT5_HUMAN" 2 2220.1162 2.13 36592 21839 2 2220.121337 1111.0654 Glyceraldehyde-3-phosphate dehydrogenase OS=Homo sapiens OX=9606 GN=GAPDH PE=1 SV=3 5.32 3495.6 - 5.86E+06 - - - 2.2931 - 2.985 0.702 - 418.2 1 2 0 0.0051 21 0 0 0 1.53E+08 7.20E+07 - - - 6.913 0.9841 221125_WJC_METTL3_EV_vs_WT_F03.21840.21840.3 3.65E-06 14/68 G.LYSSSDDVIELTPSNFNR.E sp|Q15084|PDIA6_HUMAN 1 2055.9749 1.69 36593 21840 3 2055.966624 686.3322 Protein disulfide-isomerase A6 OS=Homo sapiens OX=9606 GN=PDIA6 PE=1 SV=1 4.03 3495.6 - 2.51E+06 - - - -4.0326 - 2.667 0.55 - 164.3 1 1 0 -0.0083 18 0 0 0 7.30E+07 4.33E+07 - - - 7.1123 1 221125_WJC_METTL3_EV_vs_WT_F03.21842.21842.3 1.64E-08 23/72 R.LLAEIGAVTLVSAPR[166.11]PDSR[166.11].H "sp|Q9BSV6|SEN34_HUMAN,tr|A0A590UJ73|A0A590UJ73_HUMAN,tr|E7EQB3|E7EQB3_HUMAN,tr|A0A0G2JNK5|A0A0G2JNK5_HUMAN,tr|A0A0G2JNL0|A0A0G2JNL0_HUMAN,tr|A0A590UJW4|A0A590UJW4_HUMAN,tr|B0V3J0|B0V3J0_HUMAN" 7 1984.122 2.76 36595 21842 3 1984.117475 662.3813 tRNA-splicing endonuclease subunit Sen34 OS=Homo sapiens OX=9606 GN=TSEN34 PE=1 SV=1 6.07 3495.9 - 2.64E+06 - - - -2.2882 - 3.845 0.574 - 518.5 1 2 0 -0.0045 19 0 0 0 8.69E+07 3.15E+07 - - - 8.247 0.9994 221125_WJC_METTL3_EV_vs_WT_F03.21843.21843.3 4.49E-08 21/48 K.NLR[166.11]DIDEVSSLLR[166.11].T "sp|P50990|TCPQ_HUMAN,tr|H7C4C8|H7C4C8_HUMAN" 2 1548.8375 0.01 36596 21843 3 1548.830868 517.2864 T-complex protein 1 subunit theta OS=Homo sapiens OX=9606 GN=CCT8 PE=1 SV=4 4.56 3496 - 2.63E+06 - - - -4.2561 - 3.145 0.529 - 622.3 1 2 1 -0.0066 13 0 0 0 4.14E+05 6.09E+07 - - - 7.5426 1 221125_WJC_METTL3_EV_vs_WT_F03.21844.21844.3 1.02E-10 25/76 R.LEGWQGNPPPIYVGSSPTLK.N "sp|Q86SF2|GALT7_HUMAN,tr|H0YAK0|H0YAK0_HUMAN,tr|H0YAH3|H0YAH3_HUMAN" 3 2139.1001 1.27 36597 21844 3 2139.096744 714.0406 N-acetylgalactosaminyltransferase 7 OS=Homo sapiens OX=9606 GN=GALNT7 PE=1 SV=1 6 3496.1 - 2.45E+06 - - - -1.5483 - 4.412 0.576 - 693.2 1 2 0 -0.0033 20 0 0 0 2.46E+07 1.93E+07 - - - 8.5619 1 221125_WJC_METTL3_EV_vs_WT_F03.21845.21845.3 9.30E-07 18/52 K.SPSAQLMEQVAQLK.S "sp|Q14203|DCTN1_HUMAN,tr|A0A804CDA6|A0A804CDA6_HUMAN,tr|E7EX90|E7EX90_HUMAN,tr|A0A7P0Z4C3|A0A7P0Z4C3_HUMAN,tr|E7EWF7|E7EWF7_HUMAN" 5 1528.7919 2.01 36598 21845 3 1528.792913 510.6046 Dynactin subunit 1 OS=Homo sapiens OX=9606 GN=DCTN1 PE=1 SV=3 5.72 3496.3 - 2.39E+06 - - - 0.6443 - 2.763 0.424 - 537.6 1 2 0 0.001 14 0 0 0 9.49E+07 4.71E+07 - - - 5.9678 1 221125_WJC_METTL3_EV_vs_WT_F03.21853.21853.2 4.17E-11 18/26 K.SPSAQLMEQVAQLK[136.11].S "sp|Q14203|DCTN1_HUMAN,tr|A0A804CDA6|A0A804CDA6_HUMAN,tr|E7EX90|E7EX90_HUMAN,tr|A0A7P0Z4C3|A0A7P0Z4C3_HUMAN,tr|E7EWF7|E7EWF7_HUMAN" 5 1536.8061 2.29 36604 21853 2 1536.802331 769.4103 Dynactin subunit 1 OS=Homo sapiens OX=9606 GN=DCTN1 PE=1 SV=3 5.72 3497 - 3.18E+06 - - - -2.4707 - 3.72 0.656 - 1261.4 1 2 0 -0.0038 14 0 0 0 2.24E+08 9.82E+07 - - - 7.1817 0.8946 221125_WJC_METTL3_EV_vs_WT_F03.21854.21854.3 7.79E-05 18/68 G.LYSSSDDVIELTPSNFNR[166.11].E sp|Q15084|PDIA6_HUMAN 1 2065.9832 1.74 36605 21854 3 2065.970347 689.6683 Protein disulfide-isomerase A6 OS=Homo sapiens OX=9606 GN=PDIA6 PE=1 SV=1 4.03 3497.1 - 2.46E+06 - - - -6.214 - 2.916 0.477 - 262.4 1 1 0 -0.0128 18 0 0 0 7.30E+07 4.20E+07 - - - 6.5195 1 221125_WJC_METTL3_EV_vs_WT_F03.21855.21855.2 1.88E-08 15/34 G.LYSSSDDVIELTPSNFNR[166.11].E sp|Q15084|PDIA6_HUMAN 1 2065.9832 1.34 36606 21855 2 2065.975003 1033.9989 Protein disulfide-isomerase A6 OS=Homo sapiens OX=9606 GN=PDIA6 PE=1 SV=1 4.03 3497.3 - 2.09E+06 - - - -3.9603 - 3.333 0.637 - 423.7 1 1 0 -0.0082 18 0 0 0 4.94E+07 3.69E+07 - - - 6.7031 1 221125_WJC_METTL3_EV_vs_WT_F03.21857.21857.2 8.66E-07 15/26 K.DNTTLLTQVQTTMR.E "sp|Q13561|DCTN2_HUMAN,tr|H0YI98|H0YI98_HUMAN,tr|A8K8J9|A8K8J9_HUMAN,tr|A0A7I2V4H4|A0A7I2V4H4_HUMAN,tr|A0A7I2V4Y9|A0A7I2V4Y9_HUMAN" 5 1620.8141 9.48 36608 21857 2 1620.814546 811.4143 Dynactin subunit 2 OS=Homo sapiens OX=9606 GN=DCTN2 PE=1 SV=4 5.84 3497.5 - 1.52E+06 - - - 0.2622 - 2.904 0.662 - 878.7 1 2 0 0.0004 14 0 0 0 3.44E+07 3.63E+06 - - - 6.6057 1 221125_WJC_METTL3_EV_vs_WT_F03.21865.21865.3 1.33E-08 23/88 K.VTSVVFHPSQDLVFSASPDATIR.L sp|Q9UMS4|PRP19_HUMAN 1 2472.2649 1.61 36614 21865 3 2472.265762 825.0956 Pre-mRNA-processing factor 19 OS=Homo sapiens OX=9606 GN=PRPF19 PE=1 SV=1 5.21 3498.3 - 4.01E+06 - - - 0.3531 - 4.069 0.583 - 580.4 1 2 0 0.0009 23 0 0 0 1.39E+08 8.63E+07 - - - 8.3319 0.9999 221125_WJC_METTL3_EV_vs_WT_F03.21866.21866.3 1.49E-06 24/88 K.VTSVVFHPSQDLVFSASPDATIR[166.11].L sp|Q9UMS4|PRP19_HUMAN 1 2482.2732 1.58 36615 21866 3 2482.282421 828.4317 Pre-mRNA-processing factor 19 OS=Homo sapiens OX=9606 GN=PRPF19 PE=1 SV=1 5.21 3498.4 - 3.50E+06 - - - 3.7313 - 4.356 0.559 - 679.7 1 2 0 0.0093 23 0 0 0 1.36E+08 8.63E+07 - - - 8.2219 1 221125_WJC_METTL3_EV_vs_WT_F03.21868.21868.3 1.63E-07 23/52 K.ILESSQTLLSVLKR.E "sp|O43805|SSNA1_HUMAN,tr|A0A087WV26|A0A087WV26_HUMAN" 2 1585.9403 1.94 36617 21868 3 1585.938533 529.654 Sjoegren syndrome nuclear autoantigen 1 OS=Homo sapiens OX=9606 GN=SSNA1 PE=1 SV=2 8.75 3498.7 - 3.05E+06 - - - -1.1186 - 3.747 0.582 - 879.4 1 2 0 -0.0018 14 0 0 0 4.06E+07 2.09E+07 - - - 8.5387 1 221125_WJC_METTL3_EV_vs_WT_F03.21869.21869.2 1.46E-11 20/34 G.LYSSSDDVIELTPSNFNR.E sp|Q15084|PDIA6_HUMAN 1 2055.9749 1.34 36618 21869 2 2055.97266 1028.9947 Protein disulfide-isomerase A6 OS=Homo sapiens OX=9606 GN=PDIA6 PE=1 SV=1 4.03 3498.8 - 2.43E+06 - - - -1.0968 - 3.814 0.588 - 969.6 1 1 0 -0.0023 18 0 0 0 4.94E+07 3.69E+07 - - - 6.6745 1 221125_WJC_METTL3_EV_vs_WT_F03.21871.21871.3 3.76E-05 22/52 K.ILESSQTLLSVLK[136.11]R[166.11].E "sp|O43805|SSNA1_HUMAN,tr|A0A087WV26|A0A087WV26_HUMAN" 2 1603.9628 1.94 36620 21871 3 1603.960085 535.6615 Sjoegren syndrome nuclear autoantigen 1 OS=Homo sapiens OX=9606 GN=SSNA1 PE=1 SV=2 8.75 3499.1 - 1.93E+06 - - - -1.6783 - 2.972 0.583 - 660.1 1 2 0 -0.0027 14 0 0 0 4.06E+07 2.09E+07 - - - 7.9338 1 221125_WJC_METTL3_EV_vs_WT_F03.21873.21873.3 3.45E-05 16/56 K.DLLNHAFFQEETGVR[166.11].V "sp|Q9H4A3|WNK1_HUMAN,tr|F5GWT4|F5GWT4_HUMAN" 2 1784.8721 1.83 36622 21873 3 1784.87064 595.9646 Serine\threonine-protein kinase WNK1 OS=Homo sapiens OX=9606 GN=WNK1 PE=1 SV=2 4.65 3499.3 - 1.09E+06 - - - -0.8281 - 3.099 0.432 - 342.3 1 2 0 -0.0015 15 0 0 0 6.17E+07 3.37E+07 - - - 6.3074 1 221125_WJC_METTL3_EV_vs_WT_F03.21877.21877.2 9.64E-08 14/22 K.QDAFANFANFSK.- sp|Q14677|EPN4_HUMAN 1 1358.6255 1.6 36624 21877 2 1358.623456 680.32 Clathrin interactor 1 OS=Homo sapiens OX=9606 GN=CLINT1 PE=1 SV=1 5.84 3499.9 - 3.27E+07 - - - -1.5155 - 3.017 0.621 - 497.6 1 2 0 -0.0021 12 0 0 0 7.16E+08 4.47E+08 - - - 6.5326 1 221125_WJC_METTL3_EV_vs_WT_F03.21878.21878.2 5.08E-06 14/22 K.QDAFANFANFSK[136.11].- sp|Q14677|EPN4_HUMAN 1 1366.6397 1.6 36625 21878 2 1366.637224 684.3271 Clathrin interactor 1 OS=Homo sapiens OX=9606 GN=CLINT1 PE=1 SV=1 5.84 3499.9 - 2.14E+07 - - - -1.8227 - 3.12 0.613 - 530.7 1 2 0 -0.0025 12 0 0 0 7.16E+08 4.46E+08 - - - 6.5617 1 221125_WJC_METTL3_EV_vs_WT_F03.21879.21879.3 7.03E-11 21/80 R.VIISAPSADAPMFVMGVNHEK[136.11].Y "sp|P04406|G3P_HUMAN,tr|E7EUT5|E7EUT5_HUMAN" 2 2220.1162 1.03 36626 21879 3 2220.113909 741.046 Glyceraldehyde-3-phosphate dehydrogenase OS=Homo sapiens OX=9606 GN=GAPDH PE=1 SV=3 5.32 3499.9 - 7.31E+07 - - - -1.0526 - 3.464 0.652 - 352.9 1 2 0 -0.0023 21 0 0 0 6.04E+09 5.86E+09 - - - 8.7872 0.9996 221125_WJC_METTL3_EV_vs_WT_F03.21881.21881.2 1.22E-07 20-Dec K.SNNVEMDWVLK[136.11].H "sp|P31943|HNRH1_HUMAN,tr|E5RGH4|E5RGH4_HUMAN,tr|E7EQJ0|E7EQJ0_HUMAN,tr|D6RIH9|D6RIH9_HUMAN,tr|D6RJ04|D6RJ04_HUMAN,tr|E5RGV0|E5RGV0_HUMAN,tr|D6RFM3|D6RFM3_HUMAN,tr|E9PCY7|E9PCY7_HUMAN,tr|D6RIT2|D6RIT2_HUMAN,tr|D6R9T0|D6R9T0_HUMAN,tr|D6RIU0|D6RIU0_HUMAN,tr|H0YAQ2|H0YAQ2_HUMAN,tr|D6RAM1|D6RAM1_HUMAN,tr|D6RBM0|D6RBM0_HUMAN,tr|G8JLB6|G8JLB6_HUMAN,tr|D6RDU3|D6RDU3_HUMAN" 16 1341.6478 1.32 36628 21881 2 1341.643498 671.8312 Heterogeneous nuclear ribonucleoprotein H OS=Homo sapiens OX=9606 GN=HNRNPH1 PE=1 SV=4 4.37 3500 - 8.92E+06 - - - -3.2341 - 2.488 0.564 - 596.7 1 2 0 -0.0043 11 0 0 0 1.83E+08 1.39E+08 - - - 5.6711 1 221125_WJC_METTL3_EV_vs_WT_F03.21882.21882.2 5.37E-06 20/26 K.SPSAQLMEQVAQLK.S "sp|Q14203|DCTN1_HUMAN,tr|A0A804CDA6|A0A804CDA6_HUMAN,tr|E7EX90|E7EX90_HUMAN,tr|A0A7P0Z4C3|A0A7P0Z4C3_HUMAN,tr|E7EWF7|E7EWF7_HUMAN" 5 1528.7919 2.21 36629 21882 2 1528.789405 765.4032 Dynactin subunit 1 OS=Homo sapiens OX=9606 GN=DCTN1 PE=1 SV=3 5.72 3500.1 - 7.54E+06 - - - -1.6503 - 3.851 0.605 - 1832.3 1 2 0 -0.0025 14 0 0 0 2.17E+08 9.82E+07 - - - 6.8923 0.9999 221125_WJC_METTL3_EV_vs_WT_F03.21884.21884.3 0.000113 18/52 K.SPSAQLMEQVAQLK[136.11].S "sp|Q14203|DCTN1_HUMAN,tr|A0A804CDA6|A0A804CDA6_HUMAN,tr|E7EX90|E7EX90_HUMAN,tr|A0A7P0Z4C3|A0A7P0Z4C3_HUMAN,tr|E7EWF7|E7EWF7_HUMAN" 5 1536.8061 2.02 36631 21884 3 1536.801918 513.276 Dynactin subunit 1 OS=Homo sapiens OX=9606 GN=DCTN1 PE=1 SV=3 5.72 3500.2 - 2.83E+06 - - - -2.7394 - 3.447 0.495 - 649.9 1 2 0 -0.0042 14 0 0 0 9.52E+07 4.71E+07 - - - 7.3463 1 221125_WJC_METTL3_EV_vs_WT_F03.21886.21886.2 2.99E-11 20/38 K.PVTTPEEIAQVATISANGDK[136.11].E "sp|P10809|CH60_HUMAN,tr|A0A7I2V599|A0A7I2V599_HUMAN,tr|E7EXB4|E7EXB4_HUMAN,tr|A0A7I2YQ71|A0A7I2YQ71_HUMAN,tr|E7ESH4|E7ESH4_HUMAN,tr|A0A7I2V5M1|A0A7I2V5M1_HUMAN,tr|A0A7I2V5K3|A0A7I2V5K3_HUMAN,tr|A0A7I2V369|A0A7I2V369_HUMAN" 8 2048.0517 1.8 36633 21886 2 2048.049665 1025.0331 "60 kDa heat shock protein, mitochondrial OS=Homo sapiens OX=9606 GN=HSPD1 PE=1 SV=2" 4.14 3500.4 - 1.18E+06 - - - -1.001 - 3.843 0.708 - 941.9 1 1 0 -0.0021 20 0 0 0 1.69E+08 9.39E+07 - - - 7.5795 1 221125_WJC_METTL3_EV_vs_WT_F03.21889.21889.2 2.95E-07 14/22 K.SLNNQFASFIDK.V sp|P04264|K2C1_HUMAN 1 1382.683 14056.63 36634 21889 2 1382.68058 692.3488 "Keratin, type II cytoskeletal 1 OS=Homo sapiens OX=9606 GN=KRT1 PE=1 SV=6" 5.55 3500.8 - 6.17E+06 - - - -1.7719 - 2.666 0.592 - 628.8 1 2 0 -0.0024 12 0 0 0 2.77E+10 1.97E+06 - - - 5.9928 1 221125_WJC_METTL3_EV_vs_WT_F03.21891.21891.3 1.06E-09 17/64 K.ELQQELQEYEVVTESEK.R sp|Q96A49|SYAP1_HUMAN 1 2079.9848 0.65 36636 21891 3 2079.987829 694.3355 Synapse-associated protein 1 OS=Homo sapiens OX=9606 GN=SYAP1 PE=1 SV=1 3.9 3500.9 - 3.25E+06 - - - 1.451 - 3.277 0.545 - 478.9 1 2 0 0.003 17 0 0 0 6.80E+07 1.05E+08 - - - 7.6139 0.9956 221125_WJC_METTL3_EV_vs_WT_F03.21892.21892.3 7.32E-06 13/56 N.QLDGIHLLDPDVVAR.F sp|Q86U44|MTA70_HUMAN 1 1659.8944 0.02 36637 21892 3 1659.894229 554.3054 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 4.41 3501 - 2.90E+06 - - - -0.1151 - 2.391 0.474 - 236.8 1 1 0 -0.0002 15 0 0 0 4.69E+07 2.90E+09 - - - 6.0992 1 221125_WJC_METTL3_EV_vs_WT_F03.21893.21893.3 1.58E-08 19/48 K.TVTAMDVVYALK[136.11]R[166.11].Q sp|P62805|H4_HUMAN 1 1483.8188 0.87 36638 21893 3 1483.820402 495.6135 Histone H4 OS=Homo sapiens OX=9606 GN=H4C1 PE=1 SV=2 8.25 3501.1 - 1.79E+06 - - - 1.1093 - 2.928 0.648 - 412.5 1 2 0 0.0016 13 0 0 0 1.43E+08 1.65E+08 - - - 8.6769 1 221125_WJC_METTL3_EV_vs_WT_F03.21894.21894.2 4.13E-06 20/32 K.ELQQELQEYEVVTESEK.R sp|Q96A49|SYAP1_HUMAN 1 2079.9848 1.53 36639 21894 2 2079.983533 1040.9997 Synapse-associated protein 1 OS=Homo sapiens OX=9606 GN=SYAP1 PE=1 SV=1 3.9 3501.2 - 1.75E+06 - - - -0.6144 - 3.804 0.528 - 1333.5 1 2 0 -0.0013 17 0 0 0 1.52E+08 9.99E+07 - - - 6.2252 0.9996 221125_WJC_METTL3_EV_vs_WT_F03.21895.21895.2 0.00401 13/26 K.ETLTFPPEVPISEK.A sp|Q15208|STK38_HUMAN 1 1585.8239 13.48 36640 21895 2 1585.826074 793.9192 Serine\threonine-protein kinase 38 OS=Homo sapiens OX=9606 GN=STK38 PE=1 SV=1 4.25 3501.3 - 1.65E+06 - - - 1.3457 - 2.225 0.351 - 415.5 1 2 0 0.0021 14 0 0 0 1.17E+08 8.72E+06 - - - 3.6398 1 221125_WJC_METTL3_EV_vs_WT_F03.21898.21898.3 1.44E-05 23/56 K.FQNVADLHLYLYSAK.A "sp|P41250|GARS_HUMAN,tr|H7C443|H7C443_HUMAN,tr|A0A6Q8PGI6|A0A6Q8PGI6_HUMAN,tr|A0A6Q8PGA8|A0A6Q8PGA8_HUMAN,tr|A0A6Q8PGW4|A0A6Q8PGW4_HUMAN,tr|A0A6Q8PGZ8|A0A6Q8PGZ8_HUMAN,tr|A0A6Q8PHH9|A0A6Q8PHH9_HUMAN,tr|A0A6Q8PHI7|A0A6Q8PHI7_HUMAN,tr|A0A6Q8PFZ6|A0A6Q8PFZ6_HUMAN" 9 1780.9148 1.28 36643 21898 3 1780.918059 594.6456 Glycine--tRNA ligase OS=Homo sapiens OX=9606 GN=GARS1 PE=1 SV=3 6.74 3501.7 - 1.24E+06 - - - 1.8182 - 4.045 0.536 - 854.5 1 2 0 0.0032 15 0 0 0 2.77E+07 2.16E+07 - - - 8.1615 0.999 221125_WJC_METTL3_EV_vs_WT_F03.21899.21899.2 8.71E-08 14/24 R.ANEQEPC[160.03]GWWLAR[166.11].V "sp|P51116|FXR2_HUMAN,tr|I3L1Z2|I3L1Z2_HUMAN" 2 1625.7284 0.46 36644 21899 2 1625.721276 813.8715 Fragile X mental retardation syndrome-related protein 2 OS=Homo sapiens OX=9606 GN=FXR2 PE=1 SV=2 4.53 3501.8 - 963418 - - - -4.4011 - 2.767 0.549 - 549 1 2 0 -0.0072 13 0 0 0 6.19E+06 1.35E+07 - - - 5.7058 0.9998 221125_WJC_METTL3_EV_vs_WT_F03.21900.21900.3 0.00046 17/72 R.ILSAENIPNLPPGGGLAGK.R "sp|O75688|PPM1B_HUMAN,tr|B8ZZF0|B8ZZF0_HUMAN,tr|A0A3B3IS24|A0A3B3IS24_HUMAN,tr|C9JIR6|C9JIR6_HUMAN" 4 1817.0047 42.93 36645 21900 3 1817.00968 606.6755 Protein phosphatase 1B OS=Homo sapiens OX=9606 GN=PPM1B PE=1 SV=1 6 3501.9 - 803767 - - - 2.7413 - 2.565 0.412 - 284.5 1 2 0 0.005 19 0 0 0 9.72E+06 2.27E+05 - - - 5.4462 0.9992 221125_WJC_METTL3_EV_vs_WT_F03.21901.21901.3 0.00222 13/44 R.TR[166.11]IEGLLAAFPK[136.11].L "sp|P48444|COPD_HUMAN,tr|B0YIW6|B0YIW6_HUMAN,tr|E9PK34|E9PK34_HUMAN,tr|Q6P1Q5|Q6P1Q5_HUMAN" 4 1332.7884 0.5 36646 21901 3 1332.786251 445.2701 Coatomer subunit delta OS=Homo sapiens OX=9606 GN=ARCN1 PE=1 SV=1 8.41 3502.1 - 616349 - - - -1.6439 - 2.033 0.406 - 232.7 1 2 1 -0.0022 12 0 0 0 4.71E+06 9.45E+06 - - - 5.0326 1 221125_WJC_METTL3_EV_vs_WT_F03.21904.21904.3 7.59E-09 23/48 K.TVTAMDVVYALKR.Q sp|P62805|H4_HUMAN 1 1465.7963 0.87 36647 21904 3 1465.793901 489.606 Histone H4 OS=Homo sapiens OX=9606 GN=H4C1 PE=1 SV=2 8.25 3502.4 - 3.12E+06 - - - -1.6271 - 3.265 0.62 - 599.9 1 2 0 -0.0024 13 0 0 0 1.43E+08 1.65E+08 - - - 8.6599 1 221125_WJC_METTL3_EV_vs_WT_F03.21905.21905.3 1.38E-12 21/76 R.VPEEEKDTNVQVLMVLGAGR.G "sp|O14744|ANM5_HUMAN,tr|H0YJ77|H0YJ77_HUMAN,tr|H0YJX6|H0YJX6_HUMAN" 3 2183.1256 5.45 36648 21905 3 2183.125415 728.7158 Protein arginine N-methyltransferase 5 OS=Homo sapiens OX=9606 GN=PRMT5 PE=1 SV=4 4.41 3502.5 - 3.49E+06 - - - -0.093 - 3.974 0.642 - 569.8 1 2 1 -0.0002 20 0 0 0 1.11E+08 2.03E+07 - - - 9.045 1 221125_WJC_METTL3_EV_vs_WT_F03.21908.21908.4 4.07E-09 25/90 R.DYLHLPPEIVPATLR[166.11]R[166.11].S "sp|P46783|RS10_HUMAN,tr|A0A2R8Y6L3|A0A2R8Y6L3_HUMAN,tr|F6U211|F6U211_HUMAN,tr|A0A1W2PQS6|A0A1W2PQS6_HUMAN,tr|A0A2R8YFH6|A0A2R8YFH6_HUMAN,tr|A0A2R8Y7H1|A0A2R8Y7H1_HUMAN,tr|S4R435|S4R435_HUMAN" 7 1909.0689 1.12 36651 21908 4 1909.066215 478.2745 40S ribosomal protein S10 OS=Homo sapiens OX=9606 GN=RPS10 PE=1 SV=1 6.75 3502.8 - 1.49E+06 - - - -1.3839 - 3.71 0.591 - 477.1 1 2 0 -0.0026 16 0 0 0 1.32E+08 1.18E+08 - - - 4.8312 1 221125_WJC_METTL3_EV_vs_WT_F03.21909.21909.3 9.04E-06 13/40 R.DFK[136.11]PGDLIFAK[136.11].M sp|O75475|PSIP1_HUMAN 1 1265.6991 0.8 36652 21909 3 1265.6977 422.907 PC4 and SFRS1-interacting protein OS=Homo sapiens OX=9606 GN=PSIP1 PE=1 SV=1 5.96 3502.9 - 1.07E+06 - - - -1.0856 - 2.443 0.554 - 218.1 1 2 0 -0.0014 11 0 0 0 2.51E+07 3.15E+07 - - - 7.2537 0.9996 221125_WJC_METTL3_EV_vs_WT_F03.21913.21913.3 0.00511 Sep-44 K.QDAFANFANFSK.- sp|Q14677|EPN4_HUMAN 1 1358.6255 1.7 36656 21913 3 1358.622401 453.8824 Clathrin interactor 1 OS=Homo sapiens OX=9606 GN=CLINT1 PE=1 SV=1 5.84 3503.5 - 631055 - - - -2.292 - 1.868 0.398 - 80.4 1 2 0 -0.0031 12 0 0 0 2.97E+06 1.75E+06 - - - 4.7085 0.9981 221125_WJC_METTL3_EV_vs_WT_F03.21914.21914.3 0.0329 Nov-44 R.TRIEGLLAAFPK.L "sp|P48444|COPD_HUMAN,tr|B0YIW6|B0YIW6_HUMAN,tr|E9PK34|E9PK34_HUMAN,tr|Q6P1Q5|Q6P1Q5_HUMAN" 4 1314.766 0.5 36657 21914 3 1314.763576 439.2626 Coatomer subunit delta OS=Homo sapiens OX=9606 GN=ARCN1 PE=1 SV=1 8.41 3503.6 - 399998 - - - -1.8224 - 2.426 0.299 - 208.6 1 2 1 -0.0024 12 0 0 0 4.71E+06 9.45E+06 - - - 4.3294 1 221125_WJC_METTL3_EV_vs_WT_F03.21918.21918.4 6.24E-05 20/90 R.DYLHLPPEIVPATLRR.S "sp|P46783|RS10_HUMAN,tr|A0A2R8Y6L3|A0A2R8Y6L3_HUMAN,tr|F6U211|F6U211_HUMAN,tr|A0A1W2PQS6|A0A1W2PQS6_HUMAN,tr|A0A2R8YFH6|A0A2R8YFH6_HUMAN,tr|A0A2R8Y7H1|A0A2R8Y7H1_HUMAN,tr|S4R435|S4R435_HUMAN" 7 1889.0523 1.12 36659 21918 4 1889.050812 473.2704 40S ribosomal protein S10 OS=Homo sapiens OX=9606 GN=RPS10 PE=1 SV=1 6.75 3504.1 - 1.97E+06 - - - -0.7967 - 3.327 0.55 - 281.9 1 2 0 -0.0015 16 0 0 0 1.32E+08 1.18E+08 - - - 4.4362 1 221125_WJC_METTL3_EV_vs_WT_F03.21920.21920.2 1.44E-06 17/32 K.ELQQELQEYEVVTESEK[136.11].R sp|Q96A49|SYAP1_HUMAN 1 2087.999 1.53 36661 21920 2 2087.997049 1045.0068 Synapse-associated protein 1 OS=Homo sapiens OX=9606 GN=SYAP1 PE=1 SV=1 3.9 3504.2 - 7.29E+06 - - - -0.9397 - 3.516 0.589 - 904.5 1 2 0 -0.002 17 0 0 0 1.52E+08 9.99E+07 - - - 6.4819 0.9998 221125_WJC_METTL3_EV_vs_WT_F03.21922.21922.2 0.00912 13/20 K.LALDVEIATYR.K "sp|P48668|K2C6C_HUMAN,sp|Q01546|K22O_HUMAN,sp|P12035|K2C3_HUMAN,sp|P04259|K2C6B_HUMAN,sp|P13647|K2C5_HUMAN,sp|P35908|K22E_HUMAN,sp|O95678|K2C75_HUMAN,sp|Q5XKE5|K2C79_HUMAN,sp|P02538|K2C6A_HUMAN,tr|H0YI76|H0YI76_HUMAN,tr|H0YID6|H0YID6_HUMAN" 11 1262.6871 15.47 36663 21922 2 1262.687051 632.3508 "Keratin, type II cytoskeletal 6C OS=Homo sapiens OX=9606 GN=KRT6C PE=1 SV=3" 4.37 3504.4 - 1.77E+06 - - - -0.0016 - 2.667 0.295 - 852.2 1 2 0 0 11 0 0 0 1.17E+07 7.54E+05 - - - 3.8736 1 221125_WJC_METTL3_EV_vs_WT_F03.21924.21924.3 3.39E-05 17/40 R.DFKPGDLIFAK.M sp|O75475|PSIP1_HUMAN 1 1249.6707 0.8 36665 21924 3 1249.66923 417.5642 PC4 and SFRS1-interacting protein OS=Homo sapiens OX=9606 GN=PSIP1 PE=1 SV=1 5.96 3504.6 - 1.51E+06 - - - -1.1555 - 2.853 0.505 - 426.9 1 2 0 -0.0014 11 0 0 0 2.51E+07 3.15E+07 - - - 7.1481 0.9619 221125_WJC_METTL3_EV_vs_WT_F03.21925.21925.3 8.08E-05 15/60 K.GQLPDYTSPVVLPYSR[166.11].T "sp|Q9Y295|DRG1_HUMAN,tr|H0YI06|H0YI06_HUMAN" 2 1800.9286 0.38 36666 21925 3 1801.923866 601.3168 Developmentally-regulated GTP-binding protein 1 OS=Homo sapiens OX=9606 GN=DRG1 PE=1 SV=1 5.83 3504.7 - 1.44E+06 - - - 552.6571 - 2.438 0.398 - 167.8 1 2 0 0.9953 16 0 0 0 8.63E+06 2.28E+07 - - - 4.9883 0.9963 221125_WJC_METTL3_EV_vs_WT_F03.21926.21926.2 3.54E-06 24-Dec R.ANEQEPC[160.03]GWWLAR.V "sp|P51116|FXR2_HUMAN,tr|I3L1Z2|I3L1Z2_HUMAN" 2 1615.7202 0.46 36667 21926 2 1615.710748 808.8674 Fragile X mental retardation syndrome-related protein 2 OS=Homo sapiens OX=9606 GN=FXR2 PE=1 SV=2 4.53 3504.9 - 1.29E+06 - - - -5.8259 - 2.462 0.507 - 366.2 1 2 0 -0.0094 13 0 0 0 6.19E+06 1.35E+07 - - - 5.0951 1 221125_WJC_METTL3_EV_vs_WT_F03.21927.21927.2 9.57E-08 14/28 K.LSVFANGVVTSIQDR.Y sp|Q9NP61|ARFG3_HUMAN 1 1604.8522 0.81 36668 21927 2 1604.850633 803.4334 ADP-ribosylation factor GTPase-activating protein 3 OS=Homo sapiens OX=9606 GN=ARFGAP3 PE=1 SV=1 5.84 3505 - 1.14E+06 - - - -0.9895 - 2.945 0.597 - 812.7 1 2 0 -0.0016 15 0 0 0 2.05E+07 2.52E+07 - - - 6.1054 1 221125_WJC_METTL3_EV_vs_WT_F03.21928.21928.2 1.30E-07 14/30 K.DNSNIILLGDSQGDLR[166.11].M "sp|Q9H0P0|5NT3A_HUMAN,tr|X6RM59|X6RM59_HUMAN" 2 1738.8725 -1 36669 21928 2 1738.86924 870.4435 Cytosolic 5'-nucleotidase 3A OS=Homo sapiens OX=9606 GN=NT5C3A PE=1 SV=3 3.93 3505.1 - 1.11E+06 - - - -1.8817 - 2.822 0.623 - 709.2 1 2 0 -0.0033 16 0 0 0 0.00E+00 0.00E+00 - - - 6.1921 1 221125_WJC_METTL3_EV_vs_WT_F03.21929.21929.2 3.30E-13 19/32 R.SVFVGNIPYEATEEQLK.D "sp|P33240|CSTF2_HUMAN,sp|Q9H0L4|CSTFT_HUMAN,tr|E9PID8|E9PID8_HUMAN,tr|E7EWR4|E7EWR4_HUMAN" 4 1922.9626 19.05 36670 21929 2 1922.957433 962.4886 Cleavage stimulation factor subunit 2 OS=Homo sapiens OX=9606 GN=CSTF2 PE=1 SV=1 4.25 3505.3 - 1.01E+06 - - - -2.6657 - 3.547 0.686 - 790 1 2 0 -0.0051 17 0 0 0 6.63E+06 3.48E+05 - - - 7.219 1 221125_WJC_METTL3_EV_vs_WT_F03.21930.21930.3 2.40E-08 14/56 K.STGVFQDEELLFSHK.L "sp|Q641Q2|WAC2A_HUMAN,sp|Q9Y4E1|WAC2C_HUMAN,tr|F8W7U3|F8W7U3_HUMAN,tr|J3KP36|J3KP36_HUMAN,tr|B1AP61|B1AP61_HUMAN,tr|E7ESD2|E7ESD2_HUMAN,tr|A0A0A0MR88|A0A0A0MR88_HUMAN,tr|A0A087WYF6|A0A087WYF6_HUMAN,tr|A0A096LPC5|A0A096LPC5_HUMAN" 9 1735.8417 0.7 36671 21930 3 1735.838687 579.6212 WASH complex subunit 2A OS=Homo sapiens OX=9606 GN=WASHC2A PE=1 SV=3 4.65 3505.4 - 911442 - - - -1.7444 - 2.969 0.539 - 199.7 1 2 0 -0.003 15 0 0 0 4.46E+06 6.35E+06 - - - 7.3881 1 221125_WJC_METTL3_EV_vs_WT_F03.21932.21932.2 8.04E-08 15/34 R.C[160.03]IAVEPGNQWFVTGSADR.T sp|O43660|PLRG1_HUMAN 1 2005.9316 -1 36673 21932 2 2005.948049 1003.9731 Pleiotropic regulator 1 OS=Homo sapiens OX=9606 GN=PLRG1 PE=1 SV=1 4.37 3505.6 - 683430 - - - 8.1952 - 2.782 0.57 - 467.3 1 2 0 0.0164 18 0 0 0 0.00E+00 0.00E+00 - - - 5.7614 1 221125_WJC_METTL3_EV_vs_WT_F03.21933.21933.2 1.27E-09 14/30 K.FEGDFDFESANAQFNR.E "sp|Q9BX40|LS14B_HUMAN,tr|Q5TBP9|Q5TBP9_HUMAN,tr|Q5TBQ0|Q5TBQ0_HUMAN" 3 1892.7966 -1 36674 21933 2 1892.795894 947.4056 Protein LSM14 homolog B OS=Homo sapiens OX=9606 GN=LSM14B PE=1 SV=1 3.92 3505.8 - 542805 - - - -0.3497 - 2.579 0.728 - 466.3 1 2 0 -0.0007 16 0 0 0 0.00E+00 0.00E+00 - - - 6.747 0.9356 221125_WJC_METTL3_EV_vs_WT_F03.21936.21936.3 4.81E-05 Dec-56 N.QLDGIHLLDPDVVAR[166.11].F sp|Q86U44|MTA70_HUMAN 1 1669.9027 0.02 36675 21936 3 1669.897591 557.6415 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 4.41 3506.2 - 6.47E+06 - - - -3.0535 - 2.371 0.352 - 158.6 1 1 0 -0.0051 15 0 0 0 4.53E+07 2.90E+09 - - - 4.7157 1 221125_WJC_METTL3_EV_vs_WT_F03.21939.21939.3 2.03E-09 14/72 R.EMEENFAVEAANYQDTIGR.L "sp|P08670|VIME_HUMAN,tr|B0YJC5|B0YJC5_HUMAN,tr|B0YJC4|B0YJC4_HUMAN" 3 2185.9586 2.79 36678 21939 3 2185.954697 729.6601 Vimentin OS=Homo sapiens OX=9606 GN=VIM PE=1 SV=4 3.91 3506.3 - 7.46E+06 - - - -1.7914 - 3.078 0.65 - 286.5 1 2 0 -0.0039 19 0 0 0 1.41E+09 5.04E+08 - - - 8.5479 1 221125_WJC_METTL3_EV_vs_WT_F03.21940.21940.3 0.000402 15/44 K.SLNNQFASFIDK.V sp|P04264|K2C1_HUMAN 1 1382.683 999 36679 21940 3 1382.681499 461.9016 "Keratin, type II cytoskeletal 1 OS=Homo sapiens OX=9606 GN=KRT1 PE=1 SV=6" 5.55 3506.4 - 5.81E+06 - - - -1.1073 - 2.57 0.52 - 230.9 1 2 0 -0.0015 12 0 0 0 1.11E+08 0.00E+00 - - - 6.9534 0.9999 221125_WJC_METTL3_EV_vs_WT_F03.21941.21941.3 6.71E-07 20/64 K.LATQSNEITIPVTFESR.A "sp|P04792|HSPB1_HUMAN,tr|A0A6Q8PFK8|A0A6Q8PFK8_HUMAN,tr|C9J3N8|C9J3N8_HUMAN,tr|A0A6Q8PGK1|A0A6Q8PGK1_HUMAN" 4 1904.9844 1.69 36680 21941 3 1904.977051 636.0021 Heat shock protein beta-1 OS=Homo sapiens OX=9606 GN=HSPB1 PE=1 SV=2 4.53 3506.5 - 3.51E+06 - - - -3.8352 - 2.954 0.544 - 359.5 1 2 0 -0.0073 17 0 0 0 4.63E+08 2.74E+08 - - - 7.3394 1 221125_WJC_METTL3_EV_vs_WT_F03.21942.21942.4 2.03E-08 23/96 R.WVTYFNKPDIDAWELRK.G "sp|P20674|COX5A_HUMAN,tr|H3BNX8|H3BNX8_HUMAN,tr|H3BRI0|H3BRI0_HUMAN" 3 2180.1055 2.53 36681 21942 4 2180.106934 546.0336 "Cytochrome c oxidase subunit 5A, mitochondrial OS=Homo sapiens OX=9606 GN=COX5A PE=1 SV=2" 6.12 3506.5 - 3.49E+06 - - - 0.6692 - 3.662 0.58 - 399.5 1 2 0 0.0015 17 0 0 0 4.35E+07 1.72E+07 - - - 4.7246 1 221125_WJC_METTL3_EV_vs_WT_F03.21943.21943.2 5.98E-08 20/32 L.GNQLDGIHLLDPDVVAR[166.11].F sp|Q86U44|MTA70_HUMAN 1 1840.9671 0.02 36682 21943 2 1841.966973 921.4908 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 4.41 3506.6 - 3.18E+06 - - - 543.1341 - 3.512 0.612 - 730.7 1 1 0 0.9999 17 0 0 0 5.77E+07 3.60E+09 - - - 6.3357 1 221125_WJC_METTL3_EV_vs_WT_F03.21944.21944.2 4.00E-09 21/32 K.LATQSNEITIPVTFESR.A "sp|P04792|HSPB1_HUMAN,tr|A0A6Q8PFK8|A0A6Q8PFK8_HUMAN,tr|C9J3N8|C9J3N8_HUMAN,tr|A0A6Q8PGK1|A0A6Q8PGK1_HUMAN" 4 1904.9844 1.77 36683 21944 2 1904.983882 953.4995 Heat shock protein beta-1 OS=Homo sapiens OX=9606 GN=HSPB1 PE=1 SV=2 4.53 3506.7 - 2.84E+06 - - - -0.2493 - 3.841 0.493 - 1033.9 1 2 0 -0.0005 17 0 0 0 7.40E+08 4.19E+08 - - - 5.9907 1 221125_WJC_METTL3_EV_vs_WT_F03.21945.21945.3 1.03E-08 16/64 K.LATQSNEITIPVTFESR[166.11].A "sp|P04792|HSPB1_HUMAN,tr|A0A6Q8PFK8|A0A6Q8PFK8_HUMAN,tr|C9J3N8|C9J3N8_HUMAN,tr|A0A6Q8PGK1|A0A6Q8PGK1_HUMAN" 4 1914.9926 1.66 36684 21945 3 1914.991559 639.3382 Heat shock protein beta-1 OS=Homo sapiens OX=9606 GN=HSPB1 PE=1 SV=2 4.53 3506.8 - 2.70E+06 - - - -0.5577 - 3.012 0.54 - 241.7 1 2 0 -0.0011 17 0 0 0 4.64E+08 2.79E+08 - - - 7.3457 1 221125_WJC_METTL3_EV_vs_WT_F03.21946.21946.3 3.68E-07 16/56 K.THVADFAPEVAWVTR[166.11].S sp|P07814|SYEP_HUMAN 1 1707.8608 0.93 36685 21946 3 1707.855808 570.2942 Bifunctional glutamate\proline--tRNA ligase OS=Homo sapiens OX=9606 GN=EPRS1 PE=1 SV=5 5.29 3506.9 - 2.66E+06 - - - -2.9376 - 3.29 0.574 - 485.4 1 2 0 -0.005 15 0 0 0 7.60E+07 8.16E+07 - - - 8.0456 1 221125_WJC_METTL3_EV_vs_WT_F03.21947.21947.3 3.10E-08 17/60 K.IGDEYFTFITDC[160.03]KDPK.A "sp|P49368|TCPG_HUMAN,tr|B4DUR8|B4DUR8_HUMAN" 2 1947.8924 0.29 36686 21947 3 1947.892676 650.3048 T-complex protein 1 subunit gamma OS=Homo sapiens OX=9606 GN=CCT3 PE=1 SV=4 4.23 3507.1 - 2.45E+06 - - - 0.1258 - 2.799 0.627 - 243.9 1 2 1 0.0002 16 0 0 0 7.54E+07 2.59E+08 - - - 8.1713 1 221125_WJC_METTL3_EV_vs_WT_F03.21948.21948.2 1.41E-05 21/32 K.LATQSNEITIPVTFESR[166.11].A "sp|P04792|HSPB1_HUMAN,tr|A0A6Q8PFK8|A0A6Q8PFK8_HUMAN,tr|C9J3N8|C9J3N8_HUMAN,tr|A0A6Q8PGK1|A0A6Q8PGK1_HUMAN" 4 1914.9926 1.77 36687 21948 2 1914.994128 958.5036 Heat shock protein beta-1 OS=Homo sapiens OX=9606 GN=HSPB1 PE=1 SV=2 4.53 3507.2 - 2.35E+06 - - - 0.7838 - 3.701 0.579 - 875.4 1 2 0 0.0015 17 0 0 0 7.40E+08 4.19E+08 - - - 6.5343 0.9957 221125_WJC_METTL3_EV_vs_WT_F03.21949.21949.2 2.48E-05 13/28 K.LSVFANGVVTSIQDR[166.11].Y sp|Q9NP61|ARFG3_HUMAN 1 1614.8605 0.81 36688 21949 2 1614.851928 808.4375 ADP-ribosylation factor GTPase-activating protein 3 OS=Homo sapiens OX=9606 GN=ARFGAP3 PE=1 SV=1 5.84 3507.3 - 2.25E+06 - - - -5.3026 - 2.356 0.418 - 495.1 1 2 0 -0.0086 15 0 0 0 2.05E+07 2.52E+07 - - - 4.2325 1 221125_WJC_METTL3_EV_vs_WT_F03.21950.21950.3 6.77E-08 22/60 R.DYLHLPPEIVPATLRR.S "sp|P46783|RS10_HUMAN,tr|A0A2R8Y6L3|A0A2R8Y6L3_HUMAN,tr|F6U211|F6U211_HUMAN,tr|A0A1W2PQS6|A0A1W2PQS6_HUMAN,tr|A0A2R8YFH6|A0A2R8YFH6_HUMAN,tr|A0A2R8Y7H1|A0A2R8Y7H1_HUMAN,tr|S4R435|S4R435_HUMAN" 7 1889.0523 1.15 36689 21950 3 1889.053345 630.6914 40S ribosomal protein S10 OS=Homo sapiens OX=9606 GN=RPS10 PE=1 SV=1 6.75 3507.5 - 1.88E+06 - - - 0.5442 - 3.515 0.595 - 478.8 1 2 0 0.001 16 0 0 0 5.85E+07 5.11E+07 - - - 8.3988 0.9995 221125_WJC_METTL3_EV_vs_WT_F03.21952.21952.2 0.000316 16-Oct R.DWNTLIVGK.L "sp|O14744|ANM5_HUMAN,tr|C9JSX3|C9JSX3_HUMAN,tr|G3V580|G3V580_HUMAN,tr|G3V2L6|G3V2L6_HUMAN,tr|G3V2X6|G3V2X6_HUMAN,tr|G3V5L5|G3V5L5_HUMAN" 6 1044.5604 3.62 36691 21952 2 1044.562104 523.2875 Protein arginine N-methyltransferase 5 OS=Homo sapiens OX=9606 GN=PRMT5 PE=1 SV=4 5.84 3507.7 - 1.48E+06 - - - 1.6361 - 1.676 0.419 - 290.6 1 2 0 0.0017 9 0 0 0 2.04E+07 5.63E+06 - - - 3.6292 0.9999 221125_WJC_METTL3_EV_vs_WT_F03.21953.21953.3 0.151 18/48 R.DC[160.03]VLLQEDFLAHR.G sp|Q8IYS2|K2013_HUMAN 1 1614.7824 0.78 36692 21953 3 1614.779572 539.2681 Uncharacterized protein KIAA2013 OS=Homo sapiens OX=9606 GN=KIAA2013 PE=1 SV=1 4.54 3507.9 - 1.18E+06 - - - -1.768 - 3.172 0.381 - 350 1 2 0 -0.0029 13 0 0 0 1.25E+07 1.60E+07 - - - 5.9168 0.9999 221125_WJC_METTL3_EV_vs_WT_F03.21954.21954.3 9.79E-06 14/44 K.LSMFVLLPSHSK.D sp|Q96P63|SPB12_HUMAN 1 1357.7428 137.31 36693 21954 3 1357.742695 453.5882 Serpin B12 OS=Homo sapiens OX=9606 GN=SERPINB12 PE=1 SV=1 8.76 3508 - 946342 - - - -0.0722 - 2.466 0.433 - 258.3 1 2 0 -0.0001 12 0 0 0 8.00E+07 5.83E+05 - - - 5.8694 0.9997 221125_WJC_METTL3_EV_vs_WT_F03.21956.21956.2 3.42E-06 14/24 R.LALGSFVEEYNNK[136.11].V "sp|P61962|DCAF7_HUMAN,tr|A0A087WWI6|A0A087WWI6_HUMAN" 2 1490.7497 1.72 36694 21956 2 1490.746129 746.3821 DDB1- and CUL4-associated factor 7 OS=Homo sapiens OX=9606 GN=DCAF7 PE=1 SV=1 4.53 3508.2 - 8.63E+06 - - - -2.3679 - 2.726 0.48 - 612 1 2 0 -0.0035 13 0 0 0 3.08E+08 1.80E+08 - - - 5.159 1 221125_WJC_METTL3_EV_vs_WT_F03.21958.21958.3 5.99E-08 22/72 R.EMEENFAVEAANYQDTIGR[166.11].L "sp|P08670|VIME_HUMAN,tr|B0YJC5|B0YJC5_HUMAN,tr|B0YJC4|B0YJC4_HUMAN" 3 2195.9669 2.79 36695 21958 3 2195.956684 732.9962 Vimentin OS=Homo sapiens OX=9606 GN=VIM PE=1 SV=4 3.91 3508.4 - 1.58E+07 - - - -4.6444 - 3.486 0.654 - 721.4 1 2 0 -0.0102 19 0 0 0 1.41E+09 5.04E+08 - - - 8.8966 1 221125_WJC_METTL3_EV_vs_WT_F03.21959.21959.2 1.18E-12 17/36 R.EMEENFAVEAANYQDTIGR.L "sp|P08670|VIME_HUMAN,tr|B0YJC5|B0YJC5_HUMAN,tr|B0YJC4|B0YJC4_HUMAN" 3 2185.9586 4.28 36696 21959 2 2185.955822 1093.9866 Vimentin OS=Homo sapiens OX=9606 GN=VIM PE=1 SV=4 3.91 3508.5 - 1.14E+07 - - - -1.2768 - 3.783 0.72 - 661.2 1 2 0 -0.0028 19 0 0 0 7.74E+08 1.81E+08 - - - 7.6292 1 221125_WJC_METTL3_EV_vs_WT_F03.21962.21962.2 2.76E-08 17/30 R.ADPSLLGFSVNASSER.L "sp|Q6Y7W6|GGYF2_HUMAN,tr|A0A7I2V3H7|A0A7I2V3H7_HUMAN,tr|I1E4Y6|I1E4Y6_HUMAN,tr|A0A7I2V516|A0A7I2V516_HUMAN,tr|A0A7I2V3H0|A0A7I2V3H0_HUMAN,tr|A0A7I2V361|A0A7I2V361_HUMAN" 6 1648.8057 1.51 36699 21962 2 1648.796199 825.4101 GRB10-interacting GYF protein 2 OS=Homo sapiens OX=9606 GN=GIGYF2 PE=1 SV=1 4.37 3508.6 - 9.21E+06 - - - -5.7405 - 3.167 0.579 - 633.6 1 2 0 -0.0095 16 0 0 0 2.55E+08 1.69E+08 - - - 6.1487 0.9999 221125_WJC_METTL3_EV_vs_WT_F03.21963.21963.3 1.24E-08 18/64 K.ELQQELQEYEVVTESEK[136.11].R sp|Q96A49|SYAP1_HUMAN 1 2087.999 0.67 36700 21963 3 2087.990425 697.0069 Synapse-associated protein 1 OS=Homo sapiens OX=9606 GN=SYAP1 PE=1 SV=1 3.9 3508.6 - 7.66E+06 - - - -4.1121 - 3.435 0.609 - 615.6 1 2 0 -0.0086 17 0 0 0 7.07E+07 1.05E+08 - - - 8.4449 0.9977 221125_WJC_METTL3_EV_vs_WT_F03.21964.21964.2 0.137 22-Aug R.KENGEHDR[166.11]PADK.T "sp|A2RUR9|C144A_HUMAN,tr|A0A087WSY3|A0A087WSY3_HUMAN,tr|A6NG92|A6NG92_HUMAN,tr|C9JT67|C9JT67_HUMAN" 4 1404.6621 - 36701 21964 2 1404.659885 703.3383 Coiled-coil domain-containing protein 144A OS=Homo sapiens OX=9606 GN=CCDC144A PE=2 SV=1 5.48 3508.7 - 7.46E+06 - - - -1.5947 - 1.478 0.272 - 166 1 2 0 -0.0022 12 0 0 0 - - - - - 2.0773 0.9999 221125_WJC_METTL3_EV_vs_WT_F03.21967.21967.4 4.58E-07 25/96 R.WVTYFNK[136.11]PDIDAWELR[166.11]K[136.11].G "sp|P20674|COX5A_HUMAN,tr|H3BNX8|H3BNX8_HUMAN,tr|H3BRI0|H3BRI0_HUMAN" 3 2206.1421 2.53 36704 21967 4 2206.139555 552.5428 "Cytochrome c oxidase subunit 5A, mitochondrial OS=Homo sapiens OX=9606 GN=COX5A PE=1 SV=2" 6.12 3508.9 - 3.56E+06 - - - -1.174 - 3.633 0.453 - 461 1 2 0 -0.0026 17 0 0 0 4.35E+07 1.72E+07 - - - 3.6161 1 221125_WJC_METTL3_EV_vs_WT_F03.21968.21968.2 4.14E-10 17/32 R.TSIDAYDNFDNISLAQR[166.11].L "sp|Q00610|CLH1_HUMAN,tr|K7EJJ5|K7EJJ5_HUMAN,tr|J3KS13|J3KS13_HUMAN,tr|A0A087WVQ6|A0A087WVQ6_HUMAN" 4 1951.9151 0.97 36705 21968 2 1951.908302 976.9648 Clathrin heavy chain 1 OS=Homo sapiens OX=9606 GN=CLTC PE=1 SV=5 3.93 3509 - 2.84E+06 - - - -3.4853 - 3.49 0.667 - 1062.5 1 2 0 -0.0068 17 0 0 0 6.14E+07 6.31E+07 - - - 7.0383 1 221125_WJC_METTL3_EV_vs_WT_F03.21971.21971.3 5.46E-10 19/72 K.LQLVKEEYITSALESTEEK.L "sp|P52732|KIF11_HUMAN,tr|A0A7I2YQY4|A0A7I2YQY4_HUMAN,tr|A0A7I2V3A9|A0A7I2V3A9_HUMAN,tr|A0A7I2V3V3|A0A7I2V3V3_HUMAN" 4 2209.1366 5.15 36706 21971 3 2209.129273 737.3861 Kinesin-like protein KIF11 OS=Homo sapiens OX=9606 GN=KIF11 PE=1 SV=2 4.33 3509.4 - 1.25E+07 - - - -3.2986 - 3.481 0.625 - 469.8 1 2 1 -0.0073 19 0 0 0 1.32E+08 2.57E+07 - - - 8.5705 1 221125_WJC_METTL3_EV_vs_WT_F03.21972.21972.3 7.67E-11 19/56 K.THVADFAPEVAWVTR.S sp|P07814|SYEP_HUMAN 1 1697.8526 0.87 36707 21972 3 1697.850307 566.9581 Bifunctional glutamate\proline--tRNA ligase OS=Homo sapiens OX=9606 GN=EPRS1 PE=1 SV=5 5.29 3509.5 - 4.43E+06 - - - -1.324 - 3.692 0.611 - 726 1 2 0 -0.0022 15 0 0 0 7.80E+07 8.99E+07 - - - 8.7597 1 221125_WJC_METTL3_EV_vs_WT_F03.21973.21973.3 4.76E-09 21/76 K.PVTTPEEIAQVATISANGDK.E "sp|P10809|CH60_HUMAN,tr|A0A7I2V599|A0A7I2V599_HUMAN,tr|E7EXB4|E7EXB4_HUMAN,tr|A0A7I2YQ71|A0A7I2YQ71_HUMAN,tr|E7ESH4|E7ESH4_HUMAN,tr|A0A7I2V5M1|A0A7I2V5M1_HUMAN,tr|A0A7I2V5K3|A0A7I2V5K3_HUMAN,tr|A0A7I2V369|A0A7I2V369_HUMAN" 8 2040.0375 1.46 36708 21973 3 2040.03649 681.0198 "60 kDa heat shock protein, mitochondrial OS=Homo sapiens OX=9606 GN=HSPD1 PE=1 SV=2" 4.14 3509.6 - 1.63E+07 - - - -0.5024 - 4.724 0.607 - 665.5 1 1 0 -0.001 20 0 0 0 3.91E+08 2.68E+08 - - - 9.0739 1 221125_WJC_METTL3_EV_vs_WT_F03.21975.21975.2 8.95E-10 19/30 R.ADPSLLGFSVNASSER[166.11].L "sp|Q6Y7W6|GGYF2_HUMAN,tr|A0A7I2V3H7|A0A7I2V3H7_HUMAN,tr|I1E4Y6|I1E4Y6_HUMAN,tr|A0A7I2V516|A0A7I2V516_HUMAN,tr|A0A7I2V3H0|A0A7I2V3H0_HUMAN,tr|A0A7I2V361|A0A7I2V361_HUMAN" 6 1658.8139 1.5 36710 21975 2 1658.81262 830.4142 GRB10-interacting GYF protein 2 OS=Homo sapiens OX=9606 GN=GIGYF2 PE=1 SV=1 4.37 3509.7 - 5.12E+06 - - - -0.7921 - 3.199 0.588 - 872.1 1 2 0 -0.0013 16 0 0 0 2.55E+08 1.70E+08 - - - 6.2424 0.9974 221125_WJC_METTL3_EV_vs_WT_F03.21976.21976.3 1.14E-08 14/60 G.NQLDGIHLLDPDVVAR[166.11].F sp|Q86U44|MTA70_HUMAN 1 1783.9456 0 36711 21976 3 1783.942419 595.6558 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 4.41 3509.7 - 4.92E+06 - - - -1.7927 - 2.913 0.552 - 169.1 1 1 0 -0.0032 16 0 0 0 9.31E+05 2.63E+08 - - - 7.4367 0.9302 221125_WJC_METTL3_EV_vs_WT_F03.21984.21984.3 1.55E-09 16/64 L.GNQLDGIHLLDPDVVAR.F sp|Q86U44|MTA70_HUMAN 1 1830.9588 0.03 36717 21984 3 1831.957922 611.3269 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 4.41 3510.7 - 1.53E+07 - - - 545.6764 - 3.231 0.618 - 293.3 1 1 0 0.9991 17 0 0 0 7.88E+08 2.96E+10 - - - 8.1162 1 221125_WJC_METTL3_EV_vs_WT_F03.21985.21985.3 2.47E-06 27/72 R.IAVALEIGADLPSNHVIDR.W "sp|O14744|ANM5_HUMAN,tr|G3V580|G3V580_HUMAN,tr|G3V2X6|G3V2X6_HUMAN" 3 2002.0847 3.15 36718 21985 3 2002.079275 668.3689 Protein arginine N-methyltransferase 5 OS=Homo sapiens OX=9606 GN=PRMT5 PE=1 SV=4 4.54 3510.7 - 6.93E+06 - - - -2.7297 - 4.323 0.572 - 891.6 1 2 0 -0.0055 19 0 0 0 4.95E+08 1.57E+08 - - - 8.5124 0.9999 221125_WJC_METTL3_EV_vs_WT_F03.21986.21986.3 1.44E-08 25/72 R.IAVALEIGADLPSNHVIDR[166.11].W "sp|O14744|ANM5_HUMAN,tr|G3V580|G3V580_HUMAN,tr|G3V2X6|G3V2X6_HUMAN" 3 2012.093 3.15 36719 21986 3 2012.086895 671.7049 Protein arginine N-methyltransferase 5 OS=Homo sapiens OX=9606 GN=PRMT5 PE=1 SV=4 4.54 3510.8 - 3.14E+06 - - - -3.0391 - 3.837 0.509 - 709.7 1 2 0 -0.0061 19 0 0 0 4.95E+08 1.57E+08 - - - 7.5168 1 221125_WJC_METTL3_EV_vs_WT_F03.21987.21987.2 4.91E-12 19/32 K.LYIGNLNESVTPADLEK[136.11].V sp|Q9NZI8|IF2B1_HUMAN 1 1882.9768 1.71 36720 21987 2 1882.969213 942.4957 Insulin-like growth factor 2 mRNA-binding protein 1 OS=Homo sapiens OX=9606 GN=IGF2BP1 PE=1 SV=2 4.14 3511 - 1.75E+06 - - - -4.0075 - 3.484 0.691 - 1023.8 1 2 0 -0.0075 17 0 0 0 3.02E+08 1.77E+08 - - - 7.2111 1 221125_WJC_METTL3_EV_vs_WT_F03.21988.21988.3 2.17E-06 19/52 R.TLHLQTGNLLNWGR.L sp|P48507|GSH0_HUMAN 1 1621.8689 1.67 36721 21988 3 1621.867498 541.6302 Glutamate--cysteine ligase regulatory subunit OS=Homo sapiens OX=9606 GN=GCLM PE=1 SV=1 9.44 3511.1 - 1.45E+06 - - - -0.8484 - 3.088 0.424 - 490.8 1 2 0 -0.0014 14 0 0 0 2.72E+07 1.63E+07 - - - 6.2632 1 221125_WJC_METTL3_EV_vs_WT_F03.21991.21991.2 1.28E-10 16/32 K.LYIGNLNESVTPADLEK.V sp|Q9NZI8|IF2B1_HUMAN 1 1874.9626 1.71 36722 21991 2 1874.962329 938.4886 Insulin-like growth factor 2 mRNA-binding protein 1 OS=Homo sapiens OX=9606 GN=IGF2BP1 PE=1 SV=2 4.14 3511.5 - 3.29E+06 - - - -0.1227 - 3.34 0.647 - 631.8 1 2 0 -0.0002 17 0 0 0 3.03E+08 1.77E+08 - - - 6.7846 0.9996 221125_WJC_METTL3_EV_vs_WT_F03.21992.21992.2 0.000156 14-Aug K.DVIEEYFK.C sp|P25398|RS12_HUMAN 1 1041.5019 2.36 36723 21992 2 1041.501659 521.7582 40S ribosomal protein S12 OS=Homo sapiens OX=9606 GN=RPS12 PE=1 SV=3 4.14 3511.6 - 4.73E+06 - - - -0.2103 - 1.775 0.333 - 209.7 1 2 0 -0.0002 8 0 0 0 7.07E+07 2.99E+07 - - - 3.231 1 221125_WJC_METTL3_EV_vs_WT_F03.21995.21995.2 1.58E-09 18/34 N.PQGFNQGLDC[160.03]DVIVAEVR[166.11].S sp|Q86U44|MTA70_HUMAN 1 2025.9817 0.02 36726 21995 2 2026.98263 1013.9981 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 4.03 3511.9 - 2.81E+06 - - - 494.0247 - 3.798 0.613 - 1046.8 1 1 0 1.0009 18 0 0 0 8.18E+05 3.29E+07 - - - 6.5352 1 221125_WJC_METTL3_EV_vs_WT_F03.21996.21996.2 0.000359 19/26 Q.LDGIHLLDPDVVAR[166.11].F sp|Q86U44|MTA70_HUMAN 1 1541.8441 0.001 36727 21996 2 1541.843149 771.9293 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 4.41 3512 - 2.56E+06 - - - -0.6246 - 3.184 0.538 - 1083.2 1 1 0 -0.001 14 0 0 0 0.00E+00 1.32E+08 - - - 5.9207 0.9994 221125_WJC_METTL3_EV_vs_WT_F03.22001.22001.2 0.000158 14-Aug K.DVIEEYFK[136.11].C sp|P25398|RS12_HUMAN 1 1049.5161 2.36 36730 22001 2 1049.514759 525.7653 40S ribosomal protein S12 OS=Homo sapiens OX=9606 GN=RPS12 PE=1 SV=3 4.14 3512.6 - 2.17E+06 - - - -1.2568 - 1.587 0.366 - 207.3 1 2 0 -0.0013 8 0 0 0 7.06E+07 2.99E+07 - - - 3.1368 1 221125_WJC_METTL3_EV_vs_WT_F03.22002.22002.3 2.24E-10 23/64 R.IGGVQQDTILAEGLHFR[166.11].L "sp|Q99623|PHB2_HUMAN,tr|F5H3X6|F5H3X6_HUMAN,tr|A0A7I2V5F0|A0A7I2V5F0_HUMAN,tr|J3KPX7|J3KPX7_HUMAN,tr|F5GY37|F5GY37_HUMAN,tr|A0A3G2KQ93|A0A3G2KQ93_HUMAN,tr|F5H2D2|F5H2D2_HUMAN,tr|F5H0C5|F5H0C5_HUMAN" 8 1862.9878 1.78 36731 22002 3 1862.991047 622.0032 Prohibitin-2 OS=Homo sapiens OX=9606 GN=PHB2 PE=1 SV=2 5.32 3512.7 - 5.66E+06 - - - 1.7343 - 3.738 0.551 - 716.9 1 2 0 0.0032 17 0 0 0 3.76E+08 2.11E+08 - - - 8.0133 0.9998 221125_WJC_METTL3_EV_vs_WT_F03.22009.22009.2 2.90E-07 15/28 R.NEGNIFPNPEATFVK.E sp|Q9Y5B9|SP16H_HUMAN 1 1675.8206 2.65 36736 22009 2 1675.819219 838.9176 FACT complex subunit SPT16 OS=Homo sapiens OX=9606 GN=SUPT16H PE=1 SV=1 4.53 3513.5 - 3.45E+06 - - - -0.8157 - 2.619 0.382 - 748.3 1 2 0 -0.0014 15 0 0 0 2.23E+08 8.41E+07 - - - 4.2291 1 221125_WJC_METTL3_EV_vs_WT_F03.22010.22010.2 6.09E-11 17/28 R.NEGNIFPNPEATFVK[136.11].E sp|Q9Y5B9|SP16H_HUMAN 1 1683.8348 2.65 36737 22010 2 1683.829884 842.9247 FACT complex subunit SPT16 OS=Homo sapiens OX=9606 GN=SUPT16H PE=1 SV=1 4.53 3513.6 - 2.25E+06 - - - -2.9112 - 3.245 0.653 - 943.3 1 2 0 -0.0049 15 0 0 0 2.23E+08 8.41E+07 - - - 6.7565 1 221125_WJC_METTL3_EV_vs_WT_F03.22012.22012.2 4.44E-12 16/30 R.FMQTFVLAPEGSVANK[136.11].F "sp|Q13283|G3BP1_HUMAN,tr|A0A7I2V5M7|A0A7I2V5M7_HUMAN,tr|A0A7P0P2U7|A0A7P0P2U7_HUMAN,tr|A0A7I2YQU8|A0A7I2YQU8_HUMAN,tr|A0A7I2V651|A0A7I2V651_HUMAN,tr|A0A7I2YQN9|A0A7I2YQN9_HUMAN,tr|A0A7I2V2V1|A0A7I2V2V1_HUMAN" 7 1745.8902 1.23 36739 22012 2 1745.887487 873.9524 Ras GTPase-activating protein-binding protein 1 OS=Homo sapiens OX=9606 GN=G3BP1 PE=1 SV=1 6 3513.9 - 1.84E+06 - - - -1.5494 - 3.314 0.602 - 729.3 1 2 0 -0.0027 16 0 0 0 6.85E+07 5.56E+07 - - - 6.4322 1 221125_WJC_METTL3_EV_vs_WT_F03.22017.22017.3 2.43E-07 18/64 K.GTMTTGHNVADLVVILK.L "sp|Q12905|ILF2_HUMAN,tr|B4DY09|B4DY09_HUMAN,tr|X6R6Z1|X6R6Z1_HUMAN,tr|A0A0A0MRL0|A0A0A0MRL0_HUMAN" 4 1767.9553 0.73 36742 22017 3 1767.957906 590.3257 Interleukin enhancer-binding factor 2 OS=Homo sapiens OX=9606 GN=ILF2 PE=1 SV=2 6.74 3514.3 - 4.88E+06 - - - 1.4712 - 2.861 0.487 - 410.7 1 2 0 0.0026 17 0 0 0 1.19E+08 1.63E+08 - - - 6.6244 1 221125_WJC_METTL3_EV_vs_WT_F03.22018.22018.2 1.21E-14 21/36 R.EMEENFAVEAANYQDTIGR[166.11].L "sp|P08670|VIME_HUMAN,tr|B0YJC5|B0YJC5_HUMAN,tr|B0YJC4|B0YJC4_HUMAN" 3 2195.9669 4.28 36743 22018 2 2195.959129 1098.9907 Vimentin OS=Homo sapiens OX=9606 GN=VIM PE=1 SV=4 3.91 3514.4 - 1.49E+07 - - - -3.531 - 4.112 0.789 - 1279.1 1 2 0 -0.0078 19 0 0 0 7.73E+08 1.81E+08 - - - 8.3423 0.9881 221125_WJC_METTL3_EV_vs_WT_F03.22019.22019.2 0.000101 13/26 R.DQPAFTPSGILTPH.A sp|Q9H0D6|XRN2_HUMAN 1 1479.7358 - 36744 22019 2 1479.733298 740.8752 5'-3' exoribonuclease 2 OS=Homo sapiens OX=9606 GN=XRN2 PE=1 SV=1 5.08 3514.4 - 1.18E+07 - - - -1.6868 - 2.684 0.465 - 541.9 1 1 0 -0.0025 14 0 0 0 - - - - - 4.9523 1 221125_WJC_METTL3_EV_vs_WT_F03.22020.22020.3 3.23E-07 19/64 K.LYIGNLNESVTPADLEK.V sp|Q9NZI8|IF2B1_HUMAN 1 1874.9626 1.7 36745 22020 3 1874.959814 625.9948 Insulin-like growth factor 2 mRNA-binding protein 1 OS=Homo sapiens OX=9606 GN=IGF2BP1 PE=1 SV=2 4.14 3514.5 - 3.57E+06 - - - -1.464 - 3.057 0.516 - 246.5 1 2 0 -0.0027 17 0 0 0 9.18E+07 5.39E+07 - - - 7.1151 1 221125_WJC_METTL3_EV_vs_WT_F03.22021.22021.2 2.78E-10 17/32 R.SAELPDAVGPIVQLQEK.L "sp|Q96PU8|QKI_HUMAN,tr|F5H5U6|F5H5U6_HUMAN,tr|F5GYM3|F5GYM3_HUMAN,tr|F5GXS8|F5GXS8_HUMAN,tr|F5GYT7|F5GYT7_HUMAN,tr|F5H8C8|F5H8C8_HUMAN,tr|H0YG47|H0YG47_HUMAN" 7 1792.9571 2.34 36746 22021 2 1792.956428 897.4858 Protein quaking OS=Homo sapiens OX=9606 GN=QKI PE=1 SV=1 4.14 3514.6 - 3.26E+06 - - - -0.3636 - 3.204 0.64 - 722.6 1 2 0 -0.0007 17 0 0 0 1.95E+08 8.34E+07 - - - 6.6306 1 221125_WJC_METTL3_EV_vs_WT_F03.22024.22024.3 4.69E-06 16/64 K.GTMTTGHNVADLVVILK[136.11].L "sp|Q12905|ILF2_HUMAN,tr|B4DY09|B4DY09_HUMAN,tr|X6R6Z1|X6R6Z1_HUMAN,tr|A0A0A0MRL0|A0A0A0MRL0_HUMAN" 4 1775.9695 0.73 36747 22024 3 1775.969596 592.9971 Interleukin enhancer-binding factor 2 OS=Homo sapiens OX=9606 GN=ILF2 PE=1 SV=2 6.74 3515 - 5.65E+06 - - - 0.0512 - 2.734 0.433 - 348.6 1 2 0 0.0001 17 0 0 0 1.19E+08 1.63E+08 - - - 5.9084 1 221125_WJC_METTL3_EV_vs_WT_F03.22028.22028.2 1.77E-11 16/28 R.SVMDATQIAGLNC[160.03]LR[166.11].L "sp|P34932|HSP74_HUMAN,tr|A0A087WTS8|A0A087WTS8_HUMAN,tr|A0A087WYC1|A0A087WYC1_HUMAN" 3 1657.8155 1.08 36751 22028 2 1657.810548 829.915 Heat shock 70 kDa protein 4 OS=Homo sapiens OX=9606 GN=HSPA4 PE=1 SV=4 5.55 3515.4 - 4.78E+06 - - - -3.0058 - 3.436 0.633 - 838.6 1 2 0 -0.005 15 0 0 0 1.44E+08 1.34E+08 - - - 6.7494 0.9999 221125_WJC_METTL3_EV_vs_WT_F03.22029.22029.2 5.45E-08 14/22 R.QNNEYQVLLGIK.T sp|Q9C075|K1C23_HUMAN 1 1417.7565 999 36752 22029 2 1417.755445 709.8855 "Keratin, type I cytoskeletal 23 OS=Homo sapiens OX=9606 GN=KRT23 PE=1 SV=2" 6 3515.5 - 2.65E+06 - - - -0.7646 - 2.236 0.567 - 642.1 1 2 0 -0.0011 12 0 0 0 3.77E+07 0.00E+00 - - - 5.3458 1 221125_WJC_METTL3_EV_vs_WT_F03.22032.22032.2 0.000451 13/22 R.QAVQILDELAEK.L sp|Q99961|SH3G1_HUMAN 1 1355.7296 1.7 36753 22032 2 1355.726764 678.8721 Endophilin-A2 OS=Homo sapiens OX=9606 GN=SH3GL1 PE=1 SV=1 4.14 3515.8 - 9.81E+06 - - - -2.1258 - 2.742 0.548 - 947.9 1 2 0 -0.0029 12 0 0 0 1.71E+08 1.00E+08 - - - 5.7417 0.9998 221125_WJC_METTL3_EV_vs_WT_F03.22033.22033.2 0.00169 16-Sep K.LLQDFFNGR[166.11].D "sp|P0DMV8|HS71A_HUMAN,sp|P0DMV9|HS71B_HUMAN,tr|V9GZ37|V9GZ37_HUMAN,tr|A0A0G2JIW1|A0A0G2JIW1_HUMAN" 4 1118.5748 0.57 36754 22033 2 1118.574252 560.2947 Heat shock 70 kDa protein 1A OS=Homo sapiens OX=9606 GN=HSPA1A PE=1 SV=1 5.84 3515.9 - 5.18E+06 - - - -0.5015 - 2.059 0.375 - 255.8 1 2 0 -0.0006 9 0 0 0 7.65E+07 1.33E+08 - - - 3.9 0.9999 221125_WJC_METTL3_EV_vs_WT_F03.22038.22038.2 5.70E-06 17/28 K.EGAFSNFPISEETIK.L "sp|Q9NR30|DDX21_HUMAN,sp|Q9BQ39|DDX50_HUMAN" 2 1667.8043 0.52 36757 22038 2 1667.802082 834.9094 Nucleolar RNA helicase 2 OS=Homo sapiens OX=9606 GN=DDX21 PE=1 SV=5 4.25 3516.6 - 3.49E+06 - - - -1.3101 - 2.56 0.547 - 792.2 1 2 0 -0.0022 15 0 0 0 1.16E+08 2.21E+08 - - - 5.3915 1 221125_WJC_METTL3_EV_vs_WT_F03.22039.22039.3 1.15E-06 17/64 K.LYIGNLNESVTPADLEK[136.11].V sp|Q9NZI8|IF2B1_HUMAN 1 1882.9768 1.66 36758 22039 3 1882.974286 628.6662 Insulin-like growth factor 2 mRNA-binding protein 1 OS=Homo sapiens OX=9606 GN=IGF2BP1 PE=1 SV=2 4.14 3516.6 - 2.77E+06 - - - -1.3133 - 3.263 0.494 - 320.1 1 2 0 -0.0025 17 0 0 0 9.18E+07 5.54E+07 - - - 7.0347 1 221125_WJC_METTL3_EV_vs_WT_F03.22040.22040.3 1.19E-10 25/76 R.AINVLLEGNPDTHSWEMVGK.K "sp|Q14157|UBP2L_HUMAN,tr|Q5VU78|Q5VU78_HUMAN,tr|F8W726|F8W726_HUMAN,tr|Q5VU81|Q5VU81_HUMAN,tr|Q5VU79|Q5VU79_HUMAN,tr|Q5VU80|Q5VU80_HUMAN,tr|Q5VU77|Q5VU77_HUMAN" 7 2209.0838 2.17 36759 22040 3 2209.082112 737.3685 Ubiquitin-associated protein 2-like OS=Homo sapiens OX=9606 GN=UBAP2L PE=1 SV=2 4.65 3516.7 - 2.28E+07 - - - -0.7433 - 4.598 0.588 - 760.7 1 2 0 -0.0016 20 0 0 0 5.82E+08 2.69E+08 - - - 8.7964 1 221125_WJC_METTL3_EV_vs_WT_F03.22041.22041.2 3.21E-09 16/30 R.FMQTFVLAPEGSVANK.F "sp|Q13283|G3BP1_HUMAN,tr|A0A7I2V5M7|A0A7I2V5M7_HUMAN,tr|A0A7P0P2U7|A0A7P0P2U7_HUMAN,tr|A0A7I2YQU8|A0A7I2YQU8_HUMAN,tr|A0A7I2V651|A0A7I2V651_HUMAN,tr|A0A7I2YQN9|A0A7I2YQN9_HUMAN,tr|A0A7I2V2V1|A0A7I2V2V1_HUMAN" 7 1737.876 1.23 36760 22041 2 1737.87241 869.9453 Ras GTPase-activating protein-binding protein 1 OS=Homo sapiens OX=9606 GN=G3BP1 PE=1 SV=1 6 3516.8 - 4.21E+06 - - - -2.0611 - 3.235 0.66 - 727.5 1 2 0 -0.0036 16 0 0 0 6.85E+07 5.56E+07 - - - 6.801 1 221125_WJC_METTL3_EV_vs_WT_F03.22042.22042.3 2.12E-10 15/64 R.SAELPDAVGPIVQLQEK.L "sp|Q96PU8|QKI_HUMAN,tr|F5H5U6|F5H5U6_HUMAN,tr|F5GYM3|F5GYM3_HUMAN,tr|F5GXS8|F5GXS8_HUMAN,tr|F5GYT7|F5GYT7_HUMAN,tr|F5H8C8|F5H8C8_HUMAN,tr|H0YG47|H0YG47_HUMAN" 7 1792.9571 2.55 36761 22042 3 1792.957063 598.6596 Protein quaking OS=Homo sapiens OX=9606 GN=QKI PE=1 SV=1 4.14 3516.8 - 4.11E+06 - - - -0.0095 - 3.178 0.602 - 356 1 2 0 0 17 0 0 0 1.44E+08 5.64E+07 - - - 8.1727 1 221125_WJC_METTL3_EV_vs_WT_F03.22045.22045.2 6.90E-10 25/38 K.PVTTPEEIAQVATISANGDK.E "sp|P10809|CH60_HUMAN,tr|A0A7I2V599|A0A7I2V599_HUMAN,tr|E7EXB4|E7EXB4_HUMAN,tr|A0A7I2YQ71|A0A7I2YQ71_HUMAN,tr|E7ESH4|E7ESH4_HUMAN,tr|A0A7I2V5M1|A0A7I2V5M1_HUMAN,tr|A0A7I2V5K3|A0A7I2V5K3_HUMAN,tr|A0A7I2V369|A0A7I2V369_HUMAN" 8 2040.0375 1.57 36763 22045 2 2040.036305 1021.026 "60 kDa heat shock protein, mitochondrial OS=Homo sapiens OX=9606 GN=HSPD1 PE=1 SV=2" 4.14 3517.1 - 1.68E+06 - - - -0.5931 - 4.204 0.669 - 2115.7 1 1 0 -0.0012 20 0 0 0 1.32E+08 8.41E+07 - - - 7.5124 1 221125_WJC_METTL3_EV_vs_WT_F03.22048.22048.3 0.000234 18/68 K.ILGSGISSSSVLHGMVFK.K sp|P50990|TCPQ_HUMAN 1 1817.971 0.46 36765 22048 3 1817.97209 606.9976 T-complex protein 1 subunit theta OS=Homo sapiens OX=9606 GN=CCT8 PE=1 SV=4 8.76 3517.4 - 5.68E+06 - - - 0.6238 - 3.173 0.521 - 326 1 2 0 0.0011 18 0 0 0 8.67E+07 1.87E+08 - - - 7.2236 1 221125_WJC_METTL3_EV_vs_WT_F03.22049.22049.3 4.62E-11 21/72 K.LWSLDSDEPVADIEGHTVR.V sp|O43172|PRP4_HUMAN 1 2138.028 4.81 36766 22049 3 2138.025265 713.6833 U4\U6 small nuclear ribonucleoprotein Prp4 OS=Homo sapiens OX=9606 GN=PRPF4 PE=1 SV=2 4.1 3517.5 - 7.33E+06 - - - -1.2853 - 3.815 0.569 - 547.7 1 2 0 -0.0027 19 0 0 0 1.68E+08 3.49E+07 - - - 8.1725 1 221125_WJC_METTL3_EV_vs_WT_F03.22051.22051.2 1.66E-10 17/32 R.SAELPDAVGPIVQLQEK[136.11].L "sp|Q96PU8|QKI_HUMAN,tr|F5H5U6|F5H5U6_HUMAN,tr|F5GYM3|F5GYM3_HUMAN,tr|F5GXS8|F5GXS8_HUMAN,tr|F5GYT7|F5GYT7_HUMAN,tr|F5H8C8|F5H8C8_HUMAN,tr|H0YG47|H0YG47_HUMAN" 7 1800.9713 2.34 36768 22051 2 1800.969001 901.4929 Protein quaking OS=Homo sapiens OX=9606 GN=QKI PE=1 SV=1 4.14 3517.6 - 3.12E+06 - - - -1.2654 - 3.061 0.626 - 724.6 1 2 0 -0.0023 17 0 0 0 1.95E+08 8.34E+07 - - - 6.4144 0.9929 221125_WJC_METTL3_EV_vs_WT_F03.22053.22053.3 0.00289 17/80 R.K[136.11]HAASDVDLEIESLLNQQSTK[136.11].E "sp|Q86U44|MTA70_HUMAN,tr|F5H6D8|F5H6D8_HUMAN,tr|H0YFV6|H0YFV6_HUMAN,tr|B4DTN4|B4DTN4_HUMAN" 4 2341.2096 0.1 36770 22053 3 2341.204782 781.4105 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 4.75 3517.8 - 2.72E+06 - - - -2.066 - 2.103 0.188 - 93.9 1 2 0 -0.0048 21 0 0 0 4.31E+06 4.44E+07 - - - 2.4169 1 221125_WJC_METTL3_EV_vs_WT_F03.22056.22056.3 2.69E-07 21/64 R.SAELPDAVGPIVQLQEK[136.11].L "sp|Q96PU8|QKI_HUMAN,tr|F5H5U6|F5H5U6_HUMAN,tr|F5GYM3|F5GYM3_HUMAN,tr|F5GXS8|F5GXS8_HUMAN,tr|F5GYT7|F5GYT7_HUMAN,tr|F5H8C8|F5H8C8_HUMAN,tr|H0YG47|H0YG47_HUMAN" 7 1800.9713 2.55 36771 22056 3 1800.976302 601.331 Protein quaking OS=Homo sapiens OX=9606 GN=QKI PE=1 SV=1 4.14 3518.2 - 2.96E+06 - - - 2.7885 - 4.037 0.585 - 704 1 2 0 0.005 17 0 0 0 1.44E+08 5.64E+07 - - - 8.5862 0.9997 221125_WJC_METTL3_EV_vs_WT_F03.22058.22058.2 1.39E-06 22-Dec K.DSVVAGFQWATK[136.11].E sp|P13639|EF2_HUMAN 1 1315.6652 0.4 36773 22058 2 1315.667951 658.8399 Elongation factor 2 OS=Homo sapiens OX=9606 GN=EEF2 PE=1 SV=4 5.84 3518.4 - 2.94E+06 - - - 2.0902 - 2.428 0.473 - 535.2 1 2 0 0.0027 12 0 0 0 1.83E+07 4.56E+07 - - - 4.8677 1 221125_WJC_METTL3_EV_vs_WT_F03.22059.22059.2 1.69E-16 22/34 R.TGYESGEYEMLGEGLGVK.E "sp|Q13561|DCTN2_HUMAN,tr|H0YHL1|H0YHL1_HUMAN,tr|F8W1I6|F8W1I6_HUMAN,tr|A0A7I2V4H4|A0A7I2V4H4_HUMAN,tr|A0A7I2V390|A0A7I2V390_HUMAN,tr|A0A7I2V4Y9|A0A7I2V4Y9_HUMAN,tr|F8VRV7|F8VRV7_HUMAN,tr|F8VW18|F8VW18_HUMAN" 8 1917.8666 7.61 36774 22059 2 1917.866719 959.9406 Dynactin subunit 2 OS=Homo sapiens OX=9606 GN=DCTN2 PE=1 SV=4 4.09 3518.6 - 1.99E+06 - - - 0.0568 - 3.771 0.777 - 1101.8 1 2 0 0.0001 18 0 0 0 3.49E+07 4.59E+06 - - - 8.0432 0.9999 221125_WJC_METTL3_EV_vs_WT_F03.22069.22069.2 6.99E-08 14/30 R.TLPGSDWTPNAQFITR[166.11].S sp|P56192|SYMC_HUMAN 1 1812.9034 0.35 36782 22069 2 1812.90223 907.459 "Methionine--tRNA ligase, cytoplasmic OS=Homo sapiens OX=9606 GN=MARS1 PE=1 SV=2" 5.5 3519.8 - 2.22E+06 - - - -0.6553 - 2.505 0.585 - 409.2 1 2 0 -0.0012 16 0 0 0 1.09E+07 3.07E+07 - - - 5.6191 1 221125_WJC_METTL3_EV_vs_WT_F03.22070.22070.2 1.83E-13 25/38 R.AINVLLEGNPDTHSWEMVGK.K "sp|Q14157|UBP2L_HUMAN,tr|Q5VU78|Q5VU78_HUMAN,tr|F8W726|F8W726_HUMAN,tr|Q5VU81|Q5VU81_HUMAN,tr|Q5VU79|Q5VU79_HUMAN,tr|Q5VU80|Q5VU80_HUMAN,tr|Q5VU77|Q5VU77_HUMAN" 7 2209.0838 3.68 36783 22070 2 2209.088562 1105.5492 Ubiquitin-associated protein 2-like OS=Homo sapiens OX=9606 GN=UBAP2L PE=1 SV=2 4.65 3519.9 - 2.09E+06 - - - 2.1765 - 4.597 0.68 - 1702.7 1 2 0 0.0048 20 0 0 0 2.04E+07 5.55E+06 - - - 7.8122 0.9999 221125_WJC_METTL3_EV_vs_WT_F03.22072.22072.2 3.58E-07 13/30 K.FMQTFVLAPEGSVPNK[136.11].F "sp|Q9UN86|G3BP2_HUMAN,tr|A0A7I2V3E2|A0A7I2V3E2_HUMAN,tr|A0A7I2V647|A0A7I2V647_HUMAN,tr|D6RAC7|D6RAC7_HUMAN,tr|D6RB17|D6RB17_HUMAN,tr|A0A7I2YQS2|A0A7I2YQS2_HUMAN,tr|A0A7I2V3P9|A0A7I2V3P9_HUMAN" 7 1771.9058 1.57 36785 22072 2 1771.903792 886.9602 Ras GTPase-activating protein-binding protein 2 OS=Homo sapiens OX=9606 GN=G3BP2 PE=1 SV=2 6 3520.2 - 1.49E+06 - - - -1.1575 - 2.699 0.573 - 341.3 1 2 0 -0.0021 16 0 0 0 4.60E+07 2.92E+07 - - - 5.7136 1 221125_WJC_METTL3_EV_vs_WT_F03.22074.22074.3 6.62E-07 22/64 K.DLVLGPSGVLQGIRPGK.C "sp|Q49A26|GLYR1_HUMAN,tr|K7EMM8|K7EMM8_HUMAN" 2 1704.9887 1.63 36787 22074 3 1704.992172 569.3368 Putative oxidoreductase GLYR1 OS=Homo sapiens OX=9606 GN=GLYR1 PE=1 SV=4 8.75 3520.5 - 1.21E+06 - - - 2.0634 - 3.359 0.562 - 475.2 1 2 0 0.0035 17 0 0 0 1.85E+07 1.13E+07 - - - 7.8657 1 221125_WJC_METTL3_EV_vs_WT_F03.22081.22081.3 4.21E-05 Dec-44 K.LK[136.11]PVHGLIFLFK[136.11].W "sp|Q9Y5K5|UCHL5_HUMAN,tr|Q5LJA9|Q5LJA9_HUMAN,tr|Q5LJB0|Q5LJB0_HUMAN,tr|Q5LJA5|Q5LJA5_HUMAN" 4 1426.9035 1.59 36792 22081 3 1426.903188 476.6418 Ubiquitin carboxyl-terminal hydrolase isozyme L5 OS=Homo sapiens OX=9606 GN=UCHL5 PE=1 SV=3 10 3521.1 - 3.54E+06 - - - -0.2383 - 2.299 0.498 - 103.2 1 2 0 -0.0003 12 0 0 0 1.14E+08 7.16E+07 - - - 6.3996 1 221125_WJC_METTL3_EV_vs_WT_F03.22082.22082.2 2.03E-07 20/30 K.ANLQIDQINTDLNLER.S sp|P35579|MYH9_HUMAN 1 1868.9592 0.89 36793 22082 2 1868.958692 935.4869 Myosin-9 OS=Homo sapiens OX=9606 GN=MYH9 PE=1 SV=4 4.03 3521.3 - 3.11E+06 - - - -0.2745 - 3.666 0.583 - 1491 1 2 0 -0.0005 16 0 0 0 4.92E+07 5.51E+07 - - - 6.5408 1 221125_WJC_METTL3_EV_vs_WT_F03.22083.22083.3 2.63E-11 21/76 K.YAGSALQYEDVSTAVQNLQK[136.11].A "sp|Q9NP79|VTA1_HUMAN,tr|Q5TGM0|Q5TGM0_HUMAN,tr|A0A087WY55|A0A087WY55_HUMAN" 3 2192.0841 1.19 36794 22083 3 2192.087599 731.702 Vacuolar protein sorting-associated protein VTA1 homolog OS=Homo sapiens OX=9606 GN=VTA1 PE=1 SV=1 4.37 3521.4 - 2.58E+06 - - - 1.6062 - 3.878 0.63 - 732 1 2 0 0.0035 20 0 0 0 2.41E+07 2.02E+07 - - - 8.8509 0.9881 221125_WJC_METTL3_EV_vs_WT_F03.22085.22085.2 1.23E-11 20/38 L.GAGFGGGFAGGDGLLVGSEK.V sp|P08779|K1C16_HUMAN 1 1751.8479 999 36796 22085 2 1751.847279 876.9312 "Keratin, type I cytoskeletal 16 OS=Homo sapiens OX=9606 GN=KRT16 PE=1 SV=4" 4.37 3521.6 - 1.80E+06 - - - -0.3334 - 3.509 0.265 - 1086.4 1 1 0 -0.0006 20 0 0 0 2.94E+07 0.00E+00 - - - 4.0844 0.995 221125_WJC_METTL3_EV_vs_WT_F03.22086.22086.3 4.63E-05 16/52 T.VDNANILLQIDNAR.L "sp|Q04695|K1C17_HUMAN,tr|K7EPJ9|K7EPJ9_HUMAN,tr|F5GWP8|F5GWP8_HUMAN" 3 1567.8318 68.22 36797 22086 3 1567.833857 523.6179 "Keratin, type I cytoskeletal 17 OS=Homo sapiens OX=9606 GN=KRT17 PE=1 SV=2" 4.21 3521.7 - 1.29E+06 - - - 1.2999 - 2.748 0.45 - 504.1 1 1 0 0.002 14 0 0 0 1.46E+07 2.14E+05 - - - 6.2429 0.996 221125_WJC_METTL3_EV_vs_WT_F03.22088.22088.3 0.000659 14/44 M.LAVDAVIAELKK.Q "sp|P10809|CH60_HUMAN,tr|A0A7I2V2X6|A0A7I2V2X6_HUMAN,tr|A0A7I2V599|A0A7I2V599_HUMAN,tr|E7EXB4|E7EXB4_HUMAN,tr|A0A7I2YQ71|A0A7I2YQ71_HUMAN,tr|E7ESH4|E7ESH4_HUMAN,tr|A0A7I2V5M1|A0A7I2V5M1_HUMAN,tr|A0A7I2V5K3|A0A7I2V5K3_HUMAN,tr|A0A7I2V369|A0A7I2V369_HUMAN" 9 1268.7704 1.28 36799 22088 3 1268.768796 423.9307 "60 kDa heat shock protein, mitochondrial OS=Homo sapiens OX=9606 GN=HSPD1 PE=1 SV=2" 6.07 3522 - 1.06E+06 - - - -1.2548 - 2.649 0.459 - 369.4 1 1 0 -0.0016 12 0 0 0 7.98E+06 6.22E+06 - - - 6.3572 0.9999 221125_WJC_METTL3_EV_vs_WT_F03.22090.22090.3 0.00741 14/40 K.ELLNFYAWQHR[166.11].E sp|Q9Y3A4|RRP7A_HUMAN 1 1485.7393 0.72 36801 22090 3 1485.739148 496.2537 Ribosomal RNA-processing protein 7 homolog A OS=Homo sapiens OX=9606 GN=RRP7A PE=1 SV=2 6.85 3522.2 - 791899 - - - -0.0707 - 2.476 0.366 - 365.9 1 2 0 -0.0001 11 0 0 0 7.21E+06 9.98E+06 - - - 5.1961 0.9998 221125_WJC_METTL3_EV_vs_WT_F03.22097.22097.3 8.60E-06 Nov-60 K.ANLQIDQINTDLNLER[166.11].S sp|P35579|MYH9_HUMAN 1 1878.9675 0.92 36806 22097 3 1878.968528 627.3298 Myosin-9 OS=Homo sapiens OX=9606 GN=MYH9 PE=1 SV=4 4.03 3523.1 - 5.99E+06 - - - 0.5604 - 2.718 0.31 - 178 1 2 0 0.0011 16 0 0 0 4.48E+07 4.86E+07 - - - 4.5615 1 221125_WJC_METTL3_EV_vs_WT_F03.22099.22099.3 2.28E-07 15/60 K.ANLQIDQINTDLNLER.S sp|P35579|MYH9_HUMAN 1 1868.9592 0.94 36808 22099 3 1868.959662 623.9937 Myosin-9 OS=Homo sapiens OX=9606 GN=MYH9 PE=1 SV=4 4.03 3523.1 - 6.36E+06 - - - 0.2445 - 2.996 0.554 - 376.6 1 2 0 0.0005 16 0 0 0 4.55E+07 4.86E+07 - - - 7.5319 1 221125_WJC_METTL3_EV_vs_WT_F03.22100.22100.2 7.58E-06 17/30 K.ANLQIDQINTDLNLER[166.11].S sp|P35579|MYH9_HUMAN 1 1878.9675 0.89 36809 22100 2 1878.967297 940.491 Myosin-9 OS=Homo sapiens OX=9606 GN=MYH9 PE=1 SV=4 4.03 3523.2 - 5.07E+06 - - - -0.0947 - 3.662 0.593 - 960 1 2 0 -0.0002 16 0 0 0 4.92E+07 5.51E+07 - - - 6.6121 1 221125_WJC_METTL3_EV_vs_WT_F03.22102.22102.3 3.27E-07 15/60 R.IHFPLATYAPVISAEK[136.11].A "sp|Q6PEY2|TBA3E_HUMAN,sp|P0DPH7|TBA3C_HUMAN,sp|Q71U36|TBA1A_HUMAN,sp|P0DPH8|TBA3D_HUMAN,sp|P68366|TBA4A_HUMAN,sp|P68363|TBA1B_HUMAN,sp|Q9BQE3|TBA1C_HUMAN,tr|F8VVB9|F8VVB9_HUMAN,tr|C9JDS9|C9JDS9_HUMAN,tr|A0A1W2PQM2|A0A1W2PQM2_HUMAN,tr|F5H5D3|F5H5D3_HUMAN" 11 1763.9702 0.33 36811 22102 3 1763.97207 588.9973 Tubulin alpha-3E chain OS=Homo sapiens OX=9606 GN=TUBA3E PE=1 SV=2 6.75 3523.3 - 4.07E+06 - - - 1.0845 - 3.133 0.603 - 240 1 2 0 0.0019 16 0 0 0 2.28E+07 6.97E+07 - - - 8.1925 1 221125_WJC_METTL3_EV_vs_WT_F03.22103.22103.3 4.86E-08 16/76 K.YAGSALQYEDVSTAVQNLQK.A "sp|Q9NP79|VTA1_HUMAN,tr|Q5TGM0|Q5TGM0_HUMAN,tr|A0A087WY55|A0A087WY55_HUMAN" 3 2184.0699 1.19 36812 22103 3 2184.074475 729.0306 Vacuolar protein sorting-associated protein VTA1 homolog OS=Homo sapiens OX=9606 GN=VTA1 PE=1 SV=1 4.37 3523.3 - 4.01E+06 - - - 2.1048 - 3.127 0.523 - 402.9 1 2 0 0.0046 20 0 0 0 2.41E+07 2.02E+07 - - - 7.1355 0.9984 221125_WJC_METTL3_EV_vs_WT_F03.22104.22104.3 3.31E-07 15/60 R.LWDLEAQEEILHQEGH.S sp|O43172|PRP4_HUMAN 1 1945.917 - 36813 22104 3 1945.918718 649.6463 U4\U6 small nuclear ribonucleoprotein Prp4 OS=Homo sapiens OX=9606 GN=PRPF4 PE=1 SV=2 4.24 3523.4 - 3.43E+06 - - - 0.8798 - 2.918 0.561 - 254.7 1 1 0 0.0017 16 0 0 0 - - - - - 7.5419 1 221125_WJC_METTL3_EV_vs_WT_F03.22108.22108.2 4.25E-08 17/40 K.TIQNLYDLDEDDDGIASVPTK.Q "tr|Q8WUT1|Q8WUT1_HUMAN,tr|F8WEE2|F8WEE2_HUMAN" 2 2321.0911 1.6 36817 22108 2 2321.093106 1161.5528 POLDIP3 protein OS=Homo sapiens OX=9606 GN=POLDIP3 PE=1 SV=1 3.61 3523.8 - 1.12E+06 - - - 0.8785 - 3.896 0.699 - 479.2 1 2 0 0.002 21 0 0 0 2.41E+07 1.50E+07 - - - 7.5467 0.9999 221125_WJC_METTL3_EV_vs_WT_F03.22109.22109.3 0.000142 20/44 K.IEEIKDFLLTAR.R "sp|P63173|RL38_HUMAN,tr|J3KT73|J3KT73_HUMAN,tr|J3QL01|J3QL01_HUMAN,tr|J3KSP2|J3KSP2_HUMAN" 4 1446.8082 1.13 36818 22109 3 1446.808627 483.2767 60S ribosomal protein L38 OS=Homo sapiens OX=9606 GN=RPL38 PE=1 SV=2 4.68 3523.9 - 1.07E+06 - - - 0.2744 - 3.057 0.459 - 681.9 1 2 1 0.0004 12 0 0 0 5.14E+08 4.56E+08 - - - 6.7546 0.9979 221125_WJC_METTL3_EV_vs_WT_F03.22111.22111.3 2.89E-06 13/44 M.LAVDAVIAELK[136.11]K[136.11].Q "sp|P10809|CH60_HUMAN,tr|A0A7I2V2X6|A0A7I2V2X6_HUMAN,tr|A0A7I2V599|A0A7I2V599_HUMAN,tr|E7EXB4|E7EXB4_HUMAN,tr|A0A7I2YQ71|A0A7I2YQ71_HUMAN,tr|E7ESH4|E7ESH4_HUMAN,tr|A0A7I2V5M1|A0A7I2V5M1_HUMAN,tr|A0A7I2V5K3|A0A7I2V5K3_HUMAN,tr|A0A7I2V369|A0A7I2V369_HUMAN" 9 1284.7988 1.28 36820 22111 3 1284.799959 429.2735 "60 kDa heat shock protein, mitochondrial OS=Homo sapiens OX=9606 GN=HSPD1 PE=1 SV=2" 6.07 3524.2 - 954820 - - - 0.9114 - 2.424 0.554 - 266.7 1 1 0 0.0012 12 0 0 0 7.98E+06 6.22E+06 - - - 7.1705 0.9998 221125_WJC_METTL3_EV_vs_WT_F03.22112.22112.2 3.28E-06 14/28 K.LNPNFLQLSTGSVDK.N sp|O95628|CNOT4_HUMAN 1 1631.8519 2.97 36821 22112 2 1631.855081 816.9332 CCR4-NOT transcription complex subunit 4 OS=Homo sapiens OX=9606 GN=CNOT4 PE=1 SV=3 5.84 3524.3 - 865087 - - - 1.9579 - 2.628 0.537 - 468.2 1 2 0 0.0032 15 0 0 0 1.50E+07 5.05E+06 - - - 5.3818 1 221125_WJC_METTL3_EV_vs_WT_F03.22113.22113.3 1.91E-06 14/56 K.DSSQILSASFDQTIR.L sp|Q2TAY7|SMU1_HUMAN 1 1666.8162 0.56 36822 22113 3 1666.816652 556.6127 WD40 repeat-containing protein SMU1 OS=Homo sapiens OX=9606 GN=SMU1 PE=1 SV=2 4.21 3524.4 - 764051 - - - 0.2538 - 2.554 0.459 - 174.5 1 2 0 0.0004 15 0 0 0 6.09E+06 1.09E+07 - - - 6.104 0.957 221125_WJC_METTL3_EV_vs_WT_F03.22115.22115.2 9.14E-08 17/36 R.SIYDDISSPGLGSTPLTSR[166.11].R "sp|Q8NFH5|NUP35_HUMAN,tr|F8WCF5|F8WCF5_HUMAN,tr|F8WEL4|F8WEL4_HUMAN,tr|C9IYQ7|C9IYQ7_HUMAN" 4 1974.9774 3.2 36824 22115 2 1975.973751 988.496 Nucleoporin NUP35 OS=Homo sapiens OX=9606 GN=NUP35 PE=1 SV=1 4.21 3524.6 - 760967 - - - 504.502 - 2.443 0.464 - 593.2 1 2 0 0.9964 19 0 0 0 4.60E+07 1.44E+07 - - - 4.3513 0.9998 221125_WJC_METTL3_EV_vs_WT_F03.22116.22116.3 0.00195 14/52 R.TSGVLSQPHLPFFR.- sp|O14733|MP2K7_HUMAN 1 1584.8413 2.36 36825 22116 3 1584.844883 529.2877 Dual specificity mitogen-activated protein kinase kinase 7 OS=Homo sapiens OX=9606 GN=MAP2K7 PE=1 SV=2 9.44 3524.8 - 686519 - - - 2.2848 - 2.504 0.407 - 228.5 1 2 0 0.0036 14 0 0 0 1.84E+07 7.83E+06 - - - 5.516 0.9555 221125_WJC_METTL3_EV_vs_WT_F03.22120.22120.3 1.07E-08 14/64 L.GNQLDGIHLLDPDVVAR[166.11].F sp|Q86U44|MTA70_HUMAN 1 1840.9671 0.03 36828 22120 3 1841.968501 614.663 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 4.41 3525.2 - 2.67E+07 - - - 543.9641 - 2.887 0.59 - 200.7 1 1 0 1.0014 17 0 0 0 7.89E+08 2.97E+10 - - - 7.519 0.9999 221125_WJC_METTL3_EV_vs_WT_F03.22121.22121.3 0.000175 15/44 K.IEEIK[136.11]DFLLTAR[166.11].R "sp|P63173|RL38_HUMAN,tr|J3KT73|J3KT73_HUMAN,tr|J3QL01|J3QL01_HUMAN,tr|J3KSP2|J3KSP2_HUMAN" 4 1464.8307 1.13 36829 22121 3 1464.831177 489.2842 60S ribosomal protein L38 OS=Homo sapiens OX=9606 GN=RPL38 PE=1 SV=2 4.68 3525.2 - 1.14E+07 - - - 0.3256 - 2.78 0.475 - 402.2 1 2 1 0.0005 12 0 0 0 5.14E+08 4.56E+08 - - - 6.6697 1 221125_WJC_METTL3_EV_vs_WT_F03.22122.22122.3 1.89E-07 13/80 K.TIQNLYDLDEDDDGIASVPTK.Q "tr|Q8WUT1|Q8WUT1_HUMAN,tr|F8WEE2|F8WEE2_HUMAN" 2 2321.0911 1.65 36830 22122 3 2321.092672 774.7043 POLDIP3 protein OS=Homo sapiens OX=9606 GN=POLDIP3 PE=1 SV=1 3.61 3525.2 - 5.96E+06 - - - 0.6915 - 2.751 0.512 - 107.8 1 2 0 0.0016 21 0 0 0 6.14E+07 3.71E+07 - - - 6.674 1 221125_WJC_METTL3_EV_vs_WT_F03.22123.22123.3 3.55E-08 18/72 R.TYQELLVNQNPIAQPLASR.R "sp|Q9NX24|NHP2_HUMAN,tr|J3QSY4|J3QSY4_HUMAN,tr|D6RCB9|D6RCB9_HUMAN,tr|D6RC52|D6RC52_HUMAN" 4 2154.1433 0.84 36831 22123 3 2154.145432 719.055 H\ACA ribonucleoprotein complex subunit 2 OS=Homo sapiens OX=9606 GN=NHP2 PE=1 SV=1 5.66 3525.3 - 3.99E+06 - - - 0.9818 - 2.737 0.54 - 340.7 1 2 0 0.0021 19 0 0 0 6.13E+07 7.34E+07 - - - 7.0335 1 221125_WJC_METTL3_EV_vs_WT_F03.22124.22124.3 3.70E-08 18/72 R.TYQELLVNQNPIAQPLASR[166.11].R "sp|Q9NX24|NHP2_HUMAN,tr|J3QSY4|J3QSY4_HUMAN,tr|D6RCB9|D6RCB9_HUMAN,tr|D6RC52|D6RC52_HUMAN" 4 2164.1516 0.84 36832 22124 3 2164.15173 722.3911 H\ACA ribonucleoprotein complex subunit 2 OS=Homo sapiens OX=9606 GN=NHP2 PE=1 SV=1 5.66 3525.4 - 3.72E+06 - - - 0.0661 - 2.68 0.573 - 336.4 1 2 0 0.0001 19 0 0 0 6.13E+07 7.34E+07 - - - 7.3503 1 221125_WJC_METTL3_EV_vs_WT_F03.22125.22125.4 5.36E-08 18/126 R.APDELHYTYLDTFGR[166.11]PVIVAYK[136.11].K "sp|P04843|RPN1_HUMAN,tr|B7Z4L4|B7Z4L4_HUMAN" 2 2585.3285 1.42 36833 22125 4 2585.330421 647.3394 Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit 1 OS=Homo sapiens OX=9606 GN=RPN1 PE=1 SV=1 5.38 3525.4 - 3.47E+06 - - - 0.7446 - 3.299 0.562 - 233.2 1 2 0 0.0019 22 0 0 0 1.46E+07 1.02E+07 - - - 4.5077 1 221125_WJC_METTL3_EV_vs_WT_F03.22127.22127.3 1.00E-07 17/68 K.LEEGLVNNK[136.11]YDTALNLLK[136.11].E "sp|Q8NI36|WDR36_HUMAN,tr|A0A0A0MTB8|A0A0A0MTB8_HUMAN" 2 2062.1281 1.14 36835 22127 3 2062.13059 688.3833 WD repeat-containing protein 36 OS=Homo sapiens OX=9606 GN=WDR36 PE=1 SV=1 4.68 3525.5 - 2.23E+06 - - - 1.1973 - 3.783 0.603 - 277.2 1 2 1 0.0025 18 0 0 0 1.43E+07 1.25E+07 - - - 8.5753 1 221125_WJC_METTL3_EV_vs_WT_F03.22128.22128.3 1.03E-08 20/80 R.IAQLEEELEEEQGNTELINDR.L sp|P35579|MYH9_HUMAN 1 2471.1664 1.2 36836 22128 3 2471.166983 824.7294 Myosin-9 OS=Homo sapiens OX=9606 GN=MYH9 PE=1 SV=4 3.72 3525.6 - 2.09E+06 - - - 0.2533 - 3.761 0.583 - 608.2 1 2 0 0.0006 21 0 0 0 7.61E+07 6.36E+07 - - - 8.2156 1 221125_WJC_METTL3_EV_vs_WT_F03.22129.22129.2 2.62E-10 21/36 R.SIYDDISSPGLGSTPLTSR.R "sp|Q8NFH5|NUP35_HUMAN,tr|F8WCF5|F8WCF5_HUMAN,tr|F8WEL4|F8WEL4_HUMAN,tr|C9IYQ7|C9IYQ7_HUMAN" 4 1964.9691 3.03 36837 22129 2 1964.971265 983.4918 Nucleoporin NUP35 OS=Homo sapiens OX=9606 GN=NUP35 PE=1 SV=1 4.21 3525.8 - 2.09E+06 - - - 1.1013 - 3.424 0.699 - 925.2 1 2 0 0.0022 19 0 0 0 4.60E+07 1.51E+07 - - - 7.2291 1 221125_WJC_METTL3_EV_vs_WT_F03.22130.22130.3 5.50E-12 14/52 R.DLISHDEMFSDIYK[136.11].L "sp|P13693|TCTP_HUMAN,tr|Q5W0H4|Q5W0H4_HUMAN,tr|A0A0B4J2C3|A0A0B4J2C3_HUMAN" 3 1719.7905 1.52 36838 22130 3 1719.790155 574.2708 Translationally-controlled tumor protein OS=Homo sapiens OX=9606 GN=TPT1 PE=1 SV=1 4.22 3525.8 - 1.97E+06 - - - -0.2227 - 2.95 0.669 - 160 1 2 0 -0.0004 14 0 0 0 1.56E+07 1.02E+07 - - - 8.8735 1 221125_WJC_METTL3_EV_vs_WT_F03.22131.22131.2 4.96E-12 22/36 K.TEPTEDSGISLEMAAVTVK[136.11].E "sp|P78347|GTF2I_HUMAN,tr|A0A494C1K3|A0A494C1K3_HUMAN" 2 1984.9754 1.8 36839 22131 2 1984.973783 993.495 General transcription factor II-I OS=Homo sapiens OX=9606 GN=GTF2I PE=1 SV=2 4 3526 - 1.63E+06 - - - -0.8338 - 4.058 0.672 - 1523.1 1 2 0 -0.0017 19 0 0 0 7.13E+07 3.96E+07 - - - 7.4475 0.9995 221125_WJC_METTL3_EV_vs_WT_F03.22134.22134.3 0.000217 Nov-60 R.ELDALDANDELTPLGR.L sp|Q08211|DHX9_HUMAN 1 1740.853 -1 36842 22134 3 1740.854371 581.2916 ATP-dependent RNA helicase A OS=Homo sapiens OX=9606 GN=DHX9 PE=1 SV=4 3.77 3526.4 - 473017 - - - 0.7829 - 1.829 0.341 - 90 1 2 0 0.0014 16 0 0 0 0.00E+00 0.00E+00 - - - 3.8906 0.9014 221125_WJC_METTL3_EV_vs_WT_F03.22135.22135.2 2.76 26-Jun K.QLMSSAVQDMNC[160.03]IR[166.11].Q sp|Q96AQ2|TM125_HUMAN 1 1661.7563 0.31 36843 22135 2 1661.756988 831.8854 Transmembrane protein 125 OS=Homo sapiens OX=9606 GN=TMEM125 PE=2 SV=1 5.83 3526.5 - 451369 - - - 0.4128 - 1.009 0.012 - 67.9 1 2 0 0.0007 14 0 0 0 6.30E+06 2.04E+07 - - - -0.8481 0.9959 221125_WJC_METTL3_EV_vs_WT_F03.22139.22139.4 0.0394 13/126 R.APDELHYTYLDTFGRPVIVAYK.K "sp|P04843|RPN1_HUMAN,tr|B7Z4L4|B7Z4L4_HUMAN" 2 2567.306 1.42 36845 22139 4 2567.311569 642.8338 Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit 1 OS=Homo sapiens OX=9606 GN=RPN1 PE=1 SV=1 5.38 3526.9 - 5.32E+06 - - - 2.1591 - 2.053 0.258 - 90.4 1 2 0 0.0055 22 0 0 0 1.46E+07 1.02E+07 - - - 1.7055 1 221125_WJC_METTL3_EV_vs_WT_F03.22141.22141.3 5.75E-09 13/72 K.TEPTEDSGISLEMAAVTVK.E "sp|P78347|GTF2I_HUMAN,tr|A0A494C1K3|A0A494C1K3_HUMAN" 2 1976.9612 1.91 36847 22141 3 1976.960248 659.9944 General transcription factor II-I OS=Homo sapiens OX=9606 GN=GTF2I PE=1 SV=2 4 3527.1 - 3.57E+06 - - - -0.5008 - 2.442 0.612 - 192.2 1 2 0 -0.001 19 0 0 0 4.45E+07 2.34E+07 - - - 7.5564 1 221125_WJC_METTL3_EV_vs_WT_F03.22142.22142.3 2.52E-13 19/68 K.LEEGLVNNKYDTALNLLK.E "sp|Q8NI36|WDR36_HUMAN,tr|A0A0A0MTB8|A0A0A0MTB8_HUMAN" 2 2046.0997 1.14 36848 22142 3 2046.101956 683.0405 WD repeat-containing protein 36 OS=Homo sapiens OX=9606 GN=WDR36 PE=1 SV=1 4.68 3527.1 - 3.46E+06 - - - 1.0923 - 4.166 0.65 - 338.4 1 2 1 0.0022 18 0 0 0 1.43E+07 1.25E+07 - - - 9.3395 0.9999 221125_WJC_METTL3_EV_vs_WT_F03.22143.22143.3 5.33E-07 15/60 R.IHFPLATYAPVISAEK.A "sp|Q6PEY2|TBA3E_HUMAN,sp|P0DPH7|TBA3C_HUMAN,sp|Q71U36|TBA1A_HUMAN,sp|P0DPH8|TBA3D_HUMAN,sp|P68366|TBA4A_HUMAN,sp|P68363|TBA1B_HUMAN,sp|Q9BQE3|TBA1C_HUMAN,tr|F8VVB9|F8VVB9_HUMAN,tr|C9JDS9|C9JDS9_HUMAN,tr|A0A1W2PQM2|A0A1W2PQM2_HUMAN,tr|F5H5D3|F5H5D3_HUMAN" 11 1755.956 0.41 36849 22143 3 1755.958749 586.3259 Tubulin alpha-3E chain OS=Homo sapiens OX=9606 GN=TUBA3E PE=1 SV=2 6.75 3527.2 - 3.46E+06 - - - 1.59 - 2.687 0.463 - 256 1 2 0 0.0028 16 0 0 0 2.87E+07 6.95E+07 - - - 6.2374 1 221125_WJC_METTL3_EV_vs_WT_F03.22145.22145.3 5.50E-11 20/80 K.GAVVGIDLGTTNSC[160.03]VAVMEGK[136.11].Q "sp|P38646|GRP75_HUMAN,tr|H0Y8K0|H0Y8K0_HUMAN,tr|A0A7I2V2S7|A0A7I2V2S7_HUMAN,tr|A0A3B3ITI4|A0A3B3ITI4_HUMAN,tr|A0A7I2V3F7|A0A7I2V3F7_HUMAN,tr|D6RCD7|D6RCD7_HUMAN" 6 2085.0326 0.49 36851 22145 3 2085.03375 696.0181 "Stress-70 protein, mitochondrial OS=Homo sapiens OX=9606 GN=HSPA9 PE=1 SV=2" 4.37 3527.3 - 2.32E+06 - - - 0.5631 - 3.717 0.643 - 454.9 1 2 0 0.0012 21 0 0 0 2.11E+07 4.34E+07 - - - 8.8561 0.9999 221125_WJC_METTL3_EV_vs_WT_F03.22151.22151.3 0.179 16/40 R.FNLMAIVSDRK.M "sp|Q9Y5K5|UCHL5_HUMAN,tr|H0Y4E0|H0Y4E0_HUMAN,tr|Q5LJA9|Q5LJA9_HUMAN,tr|H0Y636|H0Y636_HUMAN,tr|H0Y6Y4|H0Y6Y4_HUMAN,tr|Q5LJB0|Q5LJB0_HUMAN,tr|Q5LJA5|Q5LJA5_HUMAN" 7 1292.6911 1.7 36857 22151 3 1292.692154 431.9043 Ubiquitin carboxyl-terminal hydrolase isozyme L5 OS=Homo sapiens OX=9606 GN=UCHL5 PE=1 SV=3 8.75 3528 - 999890 - - - 0.8215 - 2.634 0.384 - 262.9 1 2 0 0.0011 11 0 0 0 4.95E+07 2.92E+07 - - - 5.5723 0.9997 221125_WJC_METTL3_EV_vs_WT_F03.22152.22152.3 3.65E-07 Nov-44 R.DDTHYLLYIYDK.M sp|Q01780|EXOSX_HUMAN 1 1557.7351 1.1 36858 22152 3 1557.740443 520.2523 Exosome component 10 OS=Homo sapiens OX=9606 GN=EXOSC10 PE=1 SV=2 4.41 3528.1 - 894162 - - - 3.4139 - 2.232 0.452 - 176.9 1 2 0 0.0053 12 0 0 0 7.85E+06 7.13E+06 - - - 5.8034 0.9999 221125_WJC_METTL3_EV_vs_WT_F03.22153.22153.3 9.00E-09 21/68 R.LSGVPEDATK[136.11]EEILNAFR[166.11].T "sp|P78332|RBM6_HUMAN,tr|F8WCA5|F8WCA5_HUMAN,tr|E9PGM9|E9PGM9_HUMAN" 3 2006.0439 1.56 36859 22153 3 2006.041231 669.6886 RNA-binding protein 6 OS=Homo sapiens OX=9606 GN=RBM6 PE=1 SV=5 4.41 3528.2 - 749644 - - - -1.3509 - 3.436 0.452 - 535 1 2 1 -0.0027 18 0 0 0 8.59E+06 5.49E+06 - - - 6.6522 0.9999 221125_WJC_METTL3_EV_vs_WT_F03.22154.22154.3 0.000195 14/84 R.APDELHYTYLDTFGRPVIVAYK.K "sp|P04843|RPN1_HUMAN,tr|B7Z4L4|B7Z4L4_HUMAN" 2 2567.306 -1 36860 22154 3 2567.306225 856.776 Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit 1 OS=Homo sapiens OX=9606 GN=RPN1 PE=1 SV=1 5.38 3528.4 - 672600 - - - 0.0775 - 2.51 0.459 - 110 1 2 0 0.0002 22 0 0 0 0.00E+00 0.00E+00 - - - 5.8392 1 221125_WJC_METTL3_EV_vs_WT_F03.22155.22155.2 4.81E-06 20/40 R.IAQLEEELEEEQGNTELINDR[166.11].L sp|P35579|MYH9_HUMAN 1 2481.1746 1.17 36861 22155 2 2481.178222 1241.5946 Myosin-9 OS=Homo sapiens OX=9606 GN=MYH9 PE=1 SV=4 3.72 3528.5 - 633391 - - - 1.4489 - 4.252 0.592 - 1445 1 2 0 0.0036 21 0 0 0 7.14E+06 6.10E+06 - - - 6.9709 1 221125_WJC_METTL3_EV_vs_WT_F03.22156.22156.2 2.47E-11 20/36 R.TYQELLVNQNPIAQPLASR[166.11].R "sp|Q9NX24|NHP2_HUMAN,tr|J3QSY4|J3QSY4_HUMAN,tr|D6RCB9|D6RCB9_HUMAN,tr|D6RC52|D6RC52_HUMAN" 4 2164.1516 1.36 36862 22156 2 2164.154856 1083.0831 H\ACA ribonucleoprotein complex subunit 2 OS=Homo sapiens OX=9606 GN=NHP2 PE=1 SV=1 5.66 3528.6 - 576913 - - - 1.5105 - 3.988 0.664 - 1211.2 1 2 0 0.0033 19 0 0 0 7.50E+06 5.50E+06 - - - 7.3452 0.9955 221125_WJC_METTL3_EV_vs_WT_F03.22160.22160.2 0.242 13/22 K.IEEIKDFLLTAR.R "sp|P63173|RL38_HUMAN,tr|J3KT73|J3KT73_HUMAN,tr|J3QL01|J3QL01_HUMAN,tr|J3KSP2|J3KSP2_HUMAN" 4 1446.8082 1.65 36864 22160 2 1446.805865 724.4114 60S ribosomal protein L38 OS=Homo sapiens OX=9606 GN=RPL38 PE=1 SV=2 4.68 3529.1 - 1.80E+07 - - - -1.6346 - 2.568 0.315 - 730.5 1 2 1 -0.0024 12 0 0 0 1.28E+08 7.78E+07 - - - 3.8484 1 221125_WJC_METTL3_EV_vs_WT_F03.22161.22161.3 1.83E-05 16/80 R.IAQLEEELEEEQGNTELINDR[166.11].L sp|P35579|MYH9_HUMAN 1 2481.1746 1.2 36865 22161 3 2481.17571 828.0655 Myosin-9 OS=Homo sapiens OX=9606 GN=MYH9 PE=1 SV=4 3.72 3529.2 - 1.32E+07 - - - 0.4365 - 3.304 0.554 - 358.9 1 2 0 0.0011 21 0 0 0 7.61E+07 6.36E+07 - - - 7.5815 0.9978 221125_WJC_METTL3_EV_vs_WT_F03.22162.22162.2 0.00113 13/22 K.IEEIK[136.11]DFLLTAR[166.11].R "sp|P63173|RL38_HUMAN,tr|J3KT73|J3KT73_HUMAN,tr|J3QL01|J3QL01_HUMAN,tr|J3KSP2|J3KSP2_HUMAN" 4 1464.8307 1.65 36866 22162 2 1464.832592 733.4226 60S ribosomal protein L38 OS=Homo sapiens OX=9606 GN=RPL38 PE=1 SV=2 4.68 3529.2 - 1.24E+07 - - - 1.2916 - 2.669 0.424 - 754.7 1 2 1 0.0019 12 0 0 0 1.28E+08 7.78E+07 - - - 4.7551 0.9989 221125_WJC_METTL3_EV_vs_WT_F03.22164.22164.3 1.78E-07 19/56 R.SPSELFAQHIVTIVH.H "sp|Q9Y2W1|TR150_HUMAN,tr|A0A3B3ITZ9|A0A3B3ITZ9_HUMAN" 2 1676.8886 - 36868 22164 3 1676.89026 559.9701 Thyroid hormone receptor-associated protein 3 OS=Homo sapiens OX=9606 GN=THRAP3 PE=1 SV=2 5.93 3529.3 - 1.01E+07 - - - 0.9864 - 3.6 0.585 - 313.9 1 1 0 0.0017 15 0 0 0 - - - - - 8.4041 1 221125_WJC_METTL3_EV_vs_WT_F03.22166.22166.2 8.12E-12 19/40 K.GAVVGIDLGTTNSC[160.03]VAVMEGK[136.11].Q "sp|P38646|GRP75_HUMAN,tr|H0Y8K0|H0Y8K0_HUMAN,tr|A0A7I2V2S7|A0A7I2V2S7_HUMAN,tr|A0A3B3ITI4|A0A3B3ITI4_HUMAN,tr|A0A7I2V3F7|A0A7I2V3F7_HUMAN,tr|D6RCD7|D6RCD7_HUMAN" 6 2085.0326 0.34 36870 22166 2 2085.032816 1043.5236 "Stress-70 protein, mitochondrial OS=Homo sapiens OX=9606 GN=HSPA9 PE=1 SV=2" 4.37 3529.4 - 3.98E+06 - - - 0.1151 - 3.997 0.701 - 945.8 1 2 0 0.0002 21 0 0 0 8.74E+06 2.60E+07 - - - 7.6249 1 221125_WJC_METTL3_EV_vs_WT_F03.22167.22167.3 3.14E-08 14/72 R.SIYDDISSPGLGSTPLTSR.R "sp|Q8NFH5|NUP35_HUMAN,tr|F8WCF5|F8WCF5_HUMAN,tr|F8WEL4|F8WEL4_HUMAN,tr|C9IYQ7|C9IYQ7_HUMAN" 4 1964.9691 2.7 36871 22167 3 1964.972863 655.997 Nucleoporin NUP35 OS=Homo sapiens OX=9606 GN=NUP35 PE=1 SV=1 4.21 3529.5 - 3.86E+06 - - - 1.9145 - 2.434 0.555 - 182.4 1 2 0 0.0038 19 0 0 0 3.06E+07 1.14E+07 - - - 6.9121 1 221125_WJC_METTL3_EV_vs_WT_F03.22168.22168.3 1.86E-11 27/104 K.VAVAIPNR[166.11]PPDAVLTDTTSLNQAALYR[166.11].L "sp|P51659|DHB4_HUMAN,tr|A0A2R8Y7L2|A0A2R8Y7L2_HUMAN,tr|A0A2R8YD50|A0A2R8YD50_HUMAN,tr|A0A804HIR1|A0A804HIR1_HUMAN,tr|E7ET17|E7ET17_HUMAN,tr|E7EPL9|E7EPL9_HUMAN,tr|A0A804HKU2|A0A804HKU2_HUMAN,tr|A0A804HK65|A0A804HK65_HUMAN" 8 2885.5514 0.43 36872 22168 3 2885.553461 962.8577 Peroxisomal multifunctional enzyme type 2 OS=Homo sapiens OX=9606 GN=HSD17B4 PE=1 SV=3 5.93 3529.6 - 3.49E+06 - - - 0.7156 - 4.517 0.633 - 517.7 1 2 0 0.0021 27 0 0 0 1.04E+07 2.42E+07 - - - 9.0658 0.9999 221125_WJC_METTL3_EV_vs_WT_F03.22169.22169.3 0.143 16/40 R.FNLMAIVSDR[166.11]K[136.11].M "sp|Q9Y5K5|UCHL5_HUMAN,tr|H0Y4E0|H0Y4E0_HUMAN,tr|Q5LJA9|Q5LJA9_HUMAN,tr|H0Y636|H0Y636_HUMAN,tr|H0Y6Y4|H0Y6Y4_HUMAN,tr|Q5LJB0|Q5LJB0_HUMAN,tr|Q5LJA5|Q5LJA5_HUMAN" 7 1310.7136 1.7 36873 22169 3 1310.714203 437.9118 Ubiquitin carboxyl-terminal hydrolase isozyme L5 OS=Homo sapiens OX=9606 GN=UCHL5 PE=1 SV=3 8.75 3529.7 - 3.35E+06 - - - 0.489 - 2.571 0.368 - 291.6 1 2 0 0.0006 11 0 0 0 4.95E+07 2.92E+07 - - - 5.3252 1 221125_WJC_METTL3_EV_vs_WT_F03.22170.22170.2 3.41E-10 16/24 R.GDGPIC[160.03]LVLAPTR.E "sp|Q92841|DDX17_HUMAN,sp|P17844|DDX5_HUMAN,tr|A0A7I2V5F5|A0A7I2V5F5_HUMAN,tr|J3KRZ1|J3KRZ1_HUMAN,tr|A0A7I2V507|A0A7I2V507_HUMAN,tr|A0A5H1ZRQ2|A0A5H1ZRQ2_HUMAN,tr|J3KTA4|J3KTA4_HUMAN,tr|A0A0G2JLI4|A0A0G2JLI4_HUMAN,tr|A0A1X7SBZ2|A0A1X7SBZ2_HUMAN,tr|A0A7I2V2S0|A0A7I2V2S0_HUMAN,tr|J3QRQ7|J3QRQ7_HUMAN" 11 1367.7231 1.43 36874 22170 2 1367.724845 684.8688 Probable ATP-dependent RNA helicase DDX17 OS=Homo sapiens OX=9606 GN=DDX17 PE=1 SV=2 5.83 3529.8 - 2.69E+06 - - - 1.2605 - 2.703 0.638 - 873.3 1 2 0 0.0017 13 0 0 0 6.47E+07 4.53E+07 - - - 6.3048 0.8628 221125_WJC_METTL3_EV_vs_WT_F03.22173.22173.3 0.00227 13/56 R.TEIVHVWPGTDGFLK.D "sp|Q9HBF4|ZFYV1_HUMAN,tr|G3V5N8|G3V5N8_HUMAN" 2 1697.8777 1.34 36877 22173 3 1698.891529 566.9665 Zinc finger FYVE domain-containing protein 1 OS=Homo sapiens OX=9606 GN=ZFYVE1 PE=1 SV=1 5.29 3530 - 1.58E+06 - - - 597.1113 - 2.467 0.376 - 206 1 2 0 1.0138 15 0 0 0 1.16E+07 8.67E+06 - - - 4.8075 1 221125_WJC_METTL3_EV_vs_WT_F03.22174.22174.3 1.03E-16 30/104 K.VAVAIPNRPPDAVLTDTTSLNQAALYR.L "sp|P51659|DHB4_HUMAN,tr|A0A2R8Y7L2|A0A2R8Y7L2_HUMAN,tr|A0A2R8YD50|A0A2R8YD50_HUMAN,tr|A0A804HIR1|A0A804HIR1_HUMAN,tr|E7ET17|E7ET17_HUMAN,tr|E7EPL9|E7EPL9_HUMAN,tr|A0A804HKU2|A0A804HKU2_HUMAN,tr|A0A804HK65|A0A804HK65_HUMAN" 8 2865.5349 0.43 36878 22174 3 2865.537081 956.1856 Peroxisomal multifunctional enzyme type 2 OS=Homo sapiens OX=9606 GN=HSD17B4 PE=1 SV=3 5.93 3530.2 - 1.55E+06 - - - 0.7765 - 5.187 0.702 - 742.9 1 2 0 0.0022 27 0 0 0 1.04E+07 2.42E+07 - - - 10.1532 0.9998 221125_WJC_METTL3_EV_vs_WT_F03.22175.22175.3 0.000257 Sep-44 R.DDTHYLLYIYDK[136.11].M sp|Q01780|EXOSX_HUMAN 1 1565.7493 1.1 36879 22175 3 1565.751936 522.9237 Exosome component 10 OS=Homo sapiens OX=9606 GN=EXOSC10 PE=1 SV=2 4.41 3530.3 - 1.35E+06 - - - 1.6676 - 2.035 0.415 - 110.8 1 2 0 0.0026 12 0 0 0 7.85E+06 7.13E+06 - - - 5.1355 1 221125_WJC_METTL3_EV_vs_WT_F03.22176.22176.2 1.04E-08 22/40 K.GAVVGIDLGTTNSC[160.03]VAVMEGK.Q "sp|P38646|GRP75_HUMAN,tr|H0Y8K0|H0Y8K0_HUMAN,tr|A0A7I2V2S7|A0A7I2V2S7_HUMAN,tr|A0A3B3ITI4|A0A3B3ITI4_HUMAN,tr|A0A7I2V3F7|A0A7I2V3F7_HUMAN,tr|D6RCD7|D6RCD7_HUMAN" 6 2077.0184 0.34 36880 22176 2 2077.021652 1039.5165 "Stress-70 protein, mitochondrial OS=Homo sapiens OX=9606 GN=HSPA9 PE=1 SV=2" 4.37 3530.4 - 1.28E+06 - - - 1.5773 - 3.915 0.698 - 1512.4 1 2 0 0.0033 21 0 0 0 8.74E+06 2.60E+07 - - - 7.5509 1 221125_WJC_METTL3_EV_vs_WT_F03.22177.22177.2 1.90E-09 15/34 H.DLFDSGFGGGAGVETGGK[136.11].L "sp|Q86V81|THOC4_HUMAN,tr|E9PB61|E9PB61_HUMAN" 2 1677.7726 1.37 36881 22177 2 1677.763019 839.8936 THO complex subunit 4 OS=Homo sapiens OX=9606 GN=ALYREF PE=1 SV=3 4.03 3530.5 - 1.21E+06 - - - -5.6986 - 2.738 0.622 - 448.3 1 1 0 -0.0096 18 0 0 0 6.43E+06 4.70E+06 - - - 6.1084 0.9999 221125_WJC_METTL3_EV_vs_WT_F03.22181.22181.3 2.73E-08 16/60 R.AMELGR[166.11]EC[160.03]LNLWGYER[166.11].V sp|Q86U44|MTA70_HUMAN 1 2015.946 0.2 36884 22181 3 2015.946979 672.9893 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 4.79 3531 - 5.69E+06 - - - 0.4648 - 3.164 0.586 - 334.5 1 2 1 0.0009 16 0 0 0 7.05E+06 3.58E+07 - - - 8.0285 0.9999 221125_WJC_METTL3_EV_vs_WT_F03.22182.22182.3 1.22E-05 Nov-60 R.MLHFLTAVVGSTC[160.03]DVK[136.11].V "sp|Q8WWM7|ATX2L_HUMAN,tr|H3BSQ5|H3BSQ5_HUMAN,tr|H3BSK9|H3BSK9_HUMAN,tr|H3BUF6|H3BUF6_HUMAN" 4 1784.9045 1.51 36885 22182 3 1784.904518 595.9754 Ataxin-2-like protein OS=Homo sapiens OX=9606 GN=ATXN2L PE=1 SV=2 6.49 3531.1 - 1.40E+06 - - - 0.0308 - 2.116 0.474 - 117.5 1 2 0 0.0001 16 0 0 0 9.86E+06 6.52E+06 - - - 5.7478 0.9999 221125_WJC_METTL3_EV_vs_WT_F03.22183.22183.2 1.01E-05 22-Nov K.GDNITLLQSVSN.- "sp|P62304|RUXE_HUMAN,tr|A6NHK2|A6NHK2_HUMAN" 2 1259.6357 - 36886 22183 2 1259.637249 630.8251 Small nuclear ribonucleoprotein E OS=Homo sapiens OX=9606 GN=SNRPE PE=1 SV=1 3.8 3531.1 - 1.82E+07 - - - 1.194 - 2.221 0.555 - 381.3 1 2 0 0.0015 12 0 0 0 - - - - - 5.2393 1 221125_WJC_METTL3_EV_vs_WT_F03.22184.22184.3 4.71E-08 15/52 R.FHDIISDAEIEIVK.D sp|P13674|P4HA1_HUMAN 1 1627.8457 1.37 36887 22184 3 1627.846594 543.6225 Prolyl 4-hydroxylase subunit alpha-1 OS=Homo sapiens OX=9606 GN=P4HA1 PE=1 SV=2 4.31 3531.2 - 3.48E+06 - - - 0.5258 - 3.291 0.577 - 433.3 1 2 0 0.0009 14 0 0 0 1.51E+08 1.11E+08 - - - 8.1384 0.9999 221125_WJC_METTL3_EV_vs_WT_F03.22185.22185.3 0.0016 17/56 R.EVLEALGEVMVSR[166.11]PR[166.11].E "sp|Q8NE71|ABCF1_HUMAN,tr|A0A0G2JIC2|A0A0G2JIC2_HUMAN,tr|Q5STZ8|Q5STZ8_HUMAN,tr|H0YGW7|H0YGW7_HUMAN" 4 1703.9143 0.99 36888 22185 3 1703.917202 568.9787 ATP-binding cassette sub-family F member 1 OS=Homo sapiens OX=9606 GN=ABCF1 PE=1 SV=2 4.79 3531.2 - 3.06E+06 - - - 1.6849 - 3.089 0.401 - 459 1 2 0 0.0029 15 0 0 0 2.51E+07 2.55E+07 - - - 5.9529 1 221125_WJC_METTL3_EV_vs_WT_F03.22186.22186.3 2.85E-11 17/80 K.GAVVGIDLGTTNSC[160.03]VAVMEGK.Q "sp|P38646|GRP75_HUMAN,tr|H0Y8K0|H0Y8K0_HUMAN,tr|A0A7I2V2S7|A0A7I2V2S7_HUMAN,tr|A0A3B3ITI4|A0A3B3ITI4_HUMAN,tr|A0A7I2V3F7|A0A7I2V3F7_HUMAN,tr|D6RCD7|D6RCD7_HUMAN" 6 2077.0184 0.41 36889 22186 3 2077.02164 693.3467 "Stress-70 protein, mitochondrial OS=Homo sapiens OX=9606 GN=HSPA9 PE=1 SV=2" 4.37 3531.3 - 2.12E+06 - - - 1.5715 - 3.238 0.631 - 353.7 1 2 0 0.0033 21 0 0 0 1.55E+07 3.80E+07 - - - 8.391 1 221125_WJC_METTL3_EV_vs_WT_F03.22187.22187.2 4.24E-09 17/24 R.GDGPIC[160.03]LVLAPTR[166.11].E "sp|Q92841|DDX17_HUMAN,sp|P17844|DDX5_HUMAN,tr|A0A7I2V5F5|A0A7I2V5F5_HUMAN,tr|J3KRZ1|J3KRZ1_HUMAN,tr|A0A7I2V507|A0A7I2V507_HUMAN,tr|A0A5H1ZRQ2|A0A5H1ZRQ2_HUMAN,tr|J3KTA4|J3KTA4_HUMAN,tr|A0A0G2JLI4|A0A0G2JLI4_HUMAN,tr|A0A1X7SBZ2|A0A1X7SBZ2_HUMAN,tr|A0A7I2V2S0|A0A7I2V2S0_HUMAN,tr|J3QRQ7|J3QRQ7_HUMAN" 11 1377.7314 1.43 36890 22187 2 1377.733286 689.873 Probable ATP-dependent RNA helicase DDX17 OS=Homo sapiens OX=9606 GN=DDX17 PE=1 SV=2 5.83 3531.4 - 2.08E+06 - - - 1.3754 - 3.029 0.687 - 1118.8 1 2 0 0.0019 13 0 0 0 6.47E+07 4.53E+07 - - - 6.9589 1 221125_WJC_METTL3_EV_vs_WT_F03.22188.22188.3 5.22E-07 17/56 K.KIEDNNTLVFIVDVK.A "sp|P62750|RL23A_HUMAN,tr|K7EMA7|K7EMA7_HUMAN,tr|H7BY10|H7BY10_HUMAN,tr|K7ERT8|K7ERT8_HUMAN,tr|A8MUS3|A8MUS3_HUMAN,tr|K7EJV9|K7EJV9_HUMAN" 6 1745.9564 0.81 36891 22188 3 1745.959727 582.9927 60S ribosomal protein L23a OS=Homo sapiens OX=9606 GN=RPL23A PE=1 SV=1 4.56 3531.4 - 1.97E+06 - - - 1.9336 - 3.032 0.506 - 316 1 2 0 0.0034 15 0 0 0 4.02E+07 4.97E+07 - - - 7.0748 1 221125_WJC_METTL3_EV_vs_WT_F03.22189.22189.2 1.22E-12 20/32 R.VPGNIVYSSLC[160.03]GLGSEK.G "sp|Q6W2J9|BCOR_HUMAN,tr|H7BZ37|H7BZ37_HUMAN,tr|H7C2V9|H7C2V9_HUMAN,tr|A0A5F9ZGX7|A0A5F9ZGX7_HUMAN,tr|H7BYY2|H7BYY2_HUMAN,tr|H7C231|H7C231_HUMAN" 6 1778.8873 3.19 36892 22189 2 1778.890801 890.4509 BCL-6 corepressor OS=Homo sapiens OX=9606 GN=BCOR PE=1 SV=1 5.96 3531.6 - 1.63E+06 - - - 1.976 - 3.586 0.7 - 1302.8 1 2 0 0.0035 17 0 0 0 3.91E+07 1.23E+07 - - - 7.3498 1 221125_WJC_METTL3_EV_vs_WT_F03.22190.22190.3 1.16E-08 13/60 R.EFPDVLEC[160.03]TVSHAVEK.L sp|P48507|GSH0_HUMAN 1 1858.8771 2.03 36893 22190 3 1858.879601 620.633 Glutamate--cysteine ligase regulatory subunit OS=Homo sapiens OX=9606 GN=GCLM PE=1 SV=1 4.4 3531.6 - 1.03E+06 - - - 1.3374 - 2.835 0.57 - 181.7 1 2 0 0.0025 16 0 0 0 1.28E+07 6.31E+06 - - - 7.568 1 221125_WJC_METTL3_EV_vs_WT_F03.22191.22191.3 2.76E-08 16/52 K.VDLK[136.11]PLLSSLSANK[136.11].E "sp|Q9NRA8|4ET_HUMAN,tr|B1AKL4|B1AKL4_HUMAN,tr|B0QYZ7|B0QYZ7_HUMAN" 3 1499.8894 1.24 36894 22191 3 1499.889089 500.9704 Eukaryotic translation initiation factor 4E transporter OS=Homo sapiens OX=9606 GN=EIF4ENIF1 PE=1 SV=2 8.56 3531.8 - 1.02E+06 - - - -0.2033 - 3.215 0.569 - 278.7 1 2 0 -0.0003 14 0 0 0 6.75E+07 5.43E+07 - - - 7.9872 1 221125_WJC_METTL3_EV_vs_WT_F03.22193.22193.2 2.09E-16 20/40 R.IAQLEEELEEEQGNTELINDR.L sp|P35579|MYH9_HUMAN 1 2471.1664 1.17 36896 22193 2 2471.167257 1236.5905 Myosin-9 OS=Homo sapiens OX=9606 GN=MYH9 PE=1 SV=4 3.72 3532 - 831381 - - - 0.3642 - 4.339 0.734 - 909.4 1 2 0 0.0009 21 0 0 0 7.14E+06 6.10E+06 - - - 8.0703 0.9999 221125_WJC_METTL3_EV_vs_WT_F03.22194.22194.3 1.03E-07 15/52 K.VDLKPLLSSLSANK.E "sp|Q9NRA8|4ET_HUMAN,tr|B1AKL4|B1AKL4_HUMAN,tr|B0QYZ7|B0QYZ7_HUMAN" 3 1483.861 1.24 36897 22194 3 1483.861157 495.6276 Eukaryotic translation initiation factor 4E transporter OS=Homo sapiens OX=9606 GN=EIF4ENIF1 PE=1 SV=2 8.56 3532.1 - 754699 - - - 0.1098 - 2.738 0.419 - 203.3 1 2 0 0.0002 14 0 0 0 6.75E+07 5.43E+07 - - - 5.8881 1 221125_WJC_METTL3_EV_vs_WT_F03.22197.22197.2 2.32E-10 14/40 K.TIQNLYDLDEDDDGIASVPTK[136.11].Q "tr|Q8WUT1|Q8WUT1_HUMAN,tr|F8WEE2|F8WEE2_HUMAN" 2 2329.1053 1.6 36900 22197 2 2329.104648 1165.5599 POLDIP3 protein OS=Homo sapiens OX=9606 GN=POLDIP3 PE=1 SV=1 3.61 3532.5 - 585424 - - - -0.2658 - 3.214 0.674 - 322.9 1 2 0 -0.0006 21 0 0 0 2.41E+07 1.50E+07 - - - 6.8894 1 221125_WJC_METTL3_EV_vs_WT_F03.22198.22198.2 3.74E-07 13/44 R.LVGQGASAVLLDLPNSGGEAQAK[136.11].K "sp|Q99714|HCD2_HUMAN,tr|Q5H928|Q5H928_HUMAN,tr|A0A804HHW5|A0A804HHW5_HUMAN" 3 2202.1736 -1 36901 22198 2 2202.174892 1102.0941 3-hydroxyacyl-CoA dehydrogenase type-2 OS=Homo sapiens OX=9606 GN=HSD17B10 PE=1 SV=3 4.37 3532.6 - 385128 - - - 0.6044 - 3.246 0.622 - 284.3 1 2 0 0.0013 23 0 0 0 0.00E+00 0.00E+00 - - - 6.5294 0.9996 221125_WJC_METTL3_EV_vs_WT_F03.22201.22201.2 0.0456 26-Nov K.ETLTFPPEVPISEK.A sp|Q15208|STK38_HUMAN 1 1585.8239 5.42 36903 22201 2 1585.825314 793.9192 Serine\threonine-protein kinase 38 OS=Homo sapiens OX=9606 GN=STK38 PE=1 SV=1 4.25 3533 - 1.35E+06 - - - 0.8664 - 2.183 0.331 - 223.3 1 2 0 0.0014 14 0 0 0 1.58E+07 2.91E+06 - - - 3.4445 1 221125_WJC_METTL3_EV_vs_WT_F03.22203.22203.3 1.24E-08 21/92 K.IFTASNVSSVPLPAENVTITAGQR.L "sp|Q14157|UBP2L_HUMAN,tr|F8W726|F8W726_HUMAN,tr|Q5VU77|Q5VU77_HUMAN" 3 2471.302 2.4 36904 22203 3 2471.305914 824.7746 Ubiquitin-associated protein 2-like OS=Homo sapiens OX=9606 GN=UBAP2L PE=1 SV=2 6 3533.2 - 9.91E+06 - - - 1.5826 - 3.842 0.569 - 365.2 1 2 0 0.0039 24 0 0 0 6.62E+08 2.76E+08 - - - 8.0089 0.9999 221125_WJC_METTL3_EV_vs_WT_F03.22204.22204.3 4.48E-05 17/64 R.VPGNIVYSSLC[160.03]GLGSEK.G "sp|Q6W2J9|BCOR_HUMAN,tr|H7BZ37|H7BZ37_HUMAN,tr|H7C2V9|H7C2V9_HUMAN,tr|A0A5F9ZGX7|A0A5F9ZGX7_HUMAN,tr|H7BYY2|H7BYY2_HUMAN,tr|H7C231|H7C231_HUMAN" 6 1778.8873 2.46 36905 22204 3 1778.892166 593.9697 BCL-6 corepressor OS=Homo sapiens OX=9606 GN=BCOR PE=1 SV=1 5.96 3533.2 - 2.90E+06 - - - 2.7433 - 2.626 0.523 - 417.1 1 2 0 0.0049 17 0 0 0 3.41E+07 1.39E+07 - - - 6.8086 1 221125_WJC_METTL3_EV_vs_WT_F03.22205.22205.2 2.24E-09 20/34 K.VQGGALEDSQLVAGVAFK[136.11].K sp|Q99832|TCPH_HUMAN 1 1795.956 0.13 36906 22205 2 1795.956709 898.9853 T-complex protein 1 subunit eta OS=Homo sapiens OX=9606 GN=CCT7 PE=1 SV=2 4.37 3533.3 - 1.29E+07 - - - 0.4148 - 3.947 0.621 - 1510.3 1 2 0 0.0007 18 0 0 0 2.70E+07 2.13E+08 - - - 7.0029 1 221125_WJC_METTL3_EV_vs_WT_F03.22206.22206.3 7.17E-09 21/92 K.IFTASNVSSVPLPAENVTITAGQR[166.11].L "sp|Q14157|UBP2L_HUMAN,tr|F8W726|F8W726_HUMAN,tr|Q5VU77|Q5VU77_HUMAN" 3 2481.3103 2.39 36907 22206 3 2481.312724 828.1107 Ubiquitin-associated protein 2-like OS=Homo sapiens OX=9606 GN=UBAP2L PE=1 SV=2 6 3533.3 - 4.39E+06 - - - 0.9878 - 3.832 0.552 - 367.4 1 2 0 0.0025 24 0 0 0 6.62E+08 2.76E+08 - - - 7.8137 1 221125_WJC_METTL3_EV_vs_WT_F03.22207.22207.3 1.18E-11 16/60 R.FGWDC[160.03]HGLPVEYEIDK[136.11].T "sp|P41252|SYIC_HUMAN,tr|A0A804HL54|A0A804HL54_HUMAN,tr|A0A804HKU1|A0A804HKU1_HUMAN,tr|A0A804HK69|A0A804HK69_HUMAN,tr|A0A804HIV9|A0A804HIV9_HUMAN,tr|A0A804HKW6|A0A804HKW6_HUMAN,tr|A0A804HJN6|A0A804HJN6_HUMAN,tr|A0A804HHW9|A0A804HHW9_HUMAN,tr|A0A0A0MSX9|A0A0A0MSX9_HUMAN,tr|J3KR24|J3KR24_HUMAN,tr|A0A804HIG2|A0A804HIG2_HUMAN,tr|A0A804HJ36|A0A804HJ36_HUMAN" 12 1971.8916 0.98 36908 22207 3 1971.893322 658.3045 "Isoleucine--tRNA ligase, cytoplasmic OS=Homo sapiens OX=9606 GN=IARS1 PE=1 SV=2" 4.31 3533.4 - 3.43E+06 - - - 0.8484 - 3.125 0.642 - 374.9 1 2 0 0.0017 16 0 0 0 2.20E+07 2.24E+07 - - - 8.6208 1 221125_WJC_METTL3_EV_vs_WT_F03.22208.22208.3 1.17E-08 16/60 R.FGWDC[160.03]HGLPVEYEIDK.T "sp|P41252|SYIC_HUMAN,tr|A0A804HL54|A0A804HL54_HUMAN,tr|A0A804HKU1|A0A804HKU1_HUMAN,tr|A0A804HK69|A0A804HK69_HUMAN,tr|A0A804HIV9|A0A804HIV9_HUMAN,tr|A0A804HKW6|A0A804HKW6_HUMAN,tr|A0A804HJN6|A0A804HJN6_HUMAN,tr|A0A804HHW9|A0A804HHW9_HUMAN,tr|A0A0A0MSX9|A0A0A0MSX9_HUMAN,tr|J3KR24|J3KR24_HUMAN,tr|A0A804HIG2|A0A804HIG2_HUMAN,tr|A0A804HJ36|A0A804HJ36_HUMAN" 12 1963.8774 0.98 36909 22208 3 1963.878853 655.6331 "Isoleucine--tRNA ligase, cytoplasmic OS=Homo sapiens OX=9606 GN=IARS1 PE=1 SV=2" 4.31 3533.4 - 3.27E+06 - - - 0.7149 - 3.147 0.625 - 377 1 2 0 0.0014 16 0 0 0 2.20E+07 2.24E+07 - - - 8.4494 1 221125_WJC_METTL3_EV_vs_WT_F03.22210.22210.3 3.89E-06 13/72 R.VNIVFNYDMPEDSDTYLHR[166.11].V sp|O00148|DX39A_HUMAN 1 2337.0611 0.49 36911 22210 3 2337.061051 780.0276 ATP-dependent RNA helicase DDX39A OS=Homo sapiens OX=9606 GN=DDX39A PE=1 SV=2 4.22 3533.6 - 1.51E+06 - - - -0.0282 - 2.622 0.567 - 128.4 1 2 0 -0.0001 19 0 0 0 5.91E+06 1.21E+07 - - - 7.2297 1 221125_WJC_METTL3_EV_vs_WT_F03.22212.22212.4 2.25E-06 24/90 R.DYLHLPPEIVPATLR[166.11]R[166.11].S "sp|P46783|RS10_HUMAN,tr|A0A2R8Y6L3|A0A2R8Y6L3_HUMAN,tr|F6U211|F6U211_HUMAN,tr|A0A1W2PQS6|A0A1W2PQS6_HUMAN,tr|A0A2R8YFH6|A0A2R8YFH6_HUMAN,tr|A0A2R8Y7H1|A0A2R8Y7H1_HUMAN,tr|S4R435|S4R435_HUMAN" 7 1909.0689 1.19 36913 22212 4 1909.071078 478.2745 40S ribosomal protein S10 OS=Homo sapiens OX=9606 GN=RPS10 PE=1 SV=1 6.75 3533.8 - 677893 - - - 1.1634 - 2.772 0.498 - 423.5 1 2 0 0.0022 16 0 0 0 1.12E+07 9.42E+06 - - - 3.9191 0.9972 221125_WJC_METTL3_EV_vs_WT_F03.22215.22215.3 0.00743 Aug-36 R.SRGFGFVLFK.E "sp|Q14103|HNRPD_HUMAN,sp|O14979|HNRDL_HUMAN,tr|H0Y8G5|H0Y8G5_HUMAN,tr|A0A087WUK2|A0A087WUK2_HUMAN,tr|D6RF44|D6RF44_HUMAN,tr|D6RBQ9|D6RBQ9_HUMAN,tr|D6RAF8|D6RAF8_HUMAN,tr|H0YA96|H0YA96_HUMAN" 8 1156.6393 0.8 36916 22215 3 1156.639 386.5537 Heterogeneous nuclear ribonucleoprotein D0 OS=Homo sapiens OX=9606 GN=HNRNPD PE=1 SV=1 11 3534.2 - 296871 - - - -0.2715 - 1.449 0.362 - 96.3 1 2 1 -0.0003 10 0 0 0 2.25E+06 2.81E+06 - - - 3.659 1 221125_WJC_METTL3_EV_vs_WT_F03.22218.22218.3 1.42E-06 20/68 R.WFNGQPIHAELSPVTDFR[166.11].E sp|Q01081|U2AF1_HUMAN 1 2123.0464 0.1 36917 22218 3 2123.049471 708.6894 Splicing factor U2AF 35 kDa subunit OS=Homo sapiens OX=9606 GN=U2AF1 PE=1 SV=3 5.32 3534.6 - 9.29E+06 - - - 1.4493 - 2.826 0.529 - 310.6 1 2 0 0.0031 18 0 0 0 5.42E+07 5.58E+08 - - - 7.0238 1 221125_WJC_METTL3_EV_vs_WT_F03.22219.22219.2 2.18E-10 13/22 R.DFQAISDVIGNK.S sp|Q9UKL0|RCOR1_HUMAN 1 1305.6565 2.09 36918 22219 2 1305.658392 653.8355 REST corepressor 1 OS=Homo sapiens OX=9606 GN=RCOR1 PE=1 SV=2 4.21 3534.7 - 3.30E+06 - - - 1.4636 - 2.784 0.645 - 629.9 1 2 0 0.0019 12 0 0 0 3.50E+07 1.68E+07 - - - 6.4984 1 221125_WJC_METTL3_EV_vs_WT_F03.22221.22221.2 1.21E-08 17/34 K.VQGGALEDSQLVAGVAFK.K sp|Q99832|TCPH_HUMAN 1 1787.9418 0.14 36920 22221 2 1787.942156 894.9782 T-complex protein 1 subunit eta OS=Homo sapiens OX=9606 GN=CCT7 PE=1 SV=2 4.37 3534.8 - 2.31E+06 - - - 0.2192 - 3.007 0.578 - 849.1 1 2 0 0.0004 18 0 0 0 2.70E+07 1.94E+08 - - - 6.0167 1 221125_WJC_METTL3_EV_vs_WT_F03.22223.22223.3 1.23E-09 17/80 R.YLEVSEPQDIEC[160.03]C[160.03]GALEYYDK.A "sp|O15371|EIF3D_HUMAN,tr|B0QYA5|B0QYA5_HUMAN" 2 2580.1036 1.2 36922 22223 3 2580.106701 861.0418 Eukaryotic translation initiation factor 3 subunit D OS=Homo sapiens OX=9606 GN=EIF3D PE=1 SV=1 3.77 3534.9 - 2.06E+06 - - - 1.193 - 3.608 0.66 - 376.4 1 2 0 0.0031 21 0 0 0 4.27E+07 3.55E+07 - - - 8.9738 1 221125_WJC_METTL3_EV_vs_WT_F03.22225.22225.2 2.25E-07 16/28 K.GSVDSNWIVGATLEK.K sp|O96008|TOM40_HUMAN 1 1574.794 1.36 36924 22225 2 1574.799218 788.4043 Mitochondrial import receptor subunit TOM40 homolog OS=Homo sapiens OX=9606 GN=TOMM40 PE=1 SV=1 4.37 3535.1 - 1.85E+06 - - - 3.29 - 3.138 0.611 - 973.7 1 2 0 0.0052 15 0 0 0 2.21E+07 1.62E+07 - - - 6.3638 0.9999 221125_WJC_METTL3_EV_vs_WT_F03.22227.22227.3 0.000774 15/48 K.AIIEEYLHLNDMK.E "sp|Q04637|IF4G1_HUMAN,tr|E7EUU4|E7EUU4_HUMAN,tr|E9PGM1|E9PGM1_HUMAN,tr|E7EX73|E7EX73_HUMAN,tr|A0A7I2Y1C3|A0A7I2Y1C3_HUMAN" 5 1587.7967 1.38 36926 22227 3 1587.796641 530.2728 Eukaryotic translation initiation factor 4 gamma 1 OS=Homo sapiens OX=9606 GN=EIF4G1 PE=1 SV=4 4.65 3535.4 - 1.11E+06 - - - -0.0246 - 2.568 0.407 - 234.4 1 2 0 0 13 0 0 0 1.05E+07 7.59E+06 - - - 5.6347 1 221125_WJC_METTL3_EV_vs_WT_F03.22228.22228.2 1.35E-06 19/28 R.SPSELFAQHIVTIVH.H "sp|Q9Y2W1|TR150_HUMAN,tr|A0A3B3ITZ9|A0A3B3ITZ9_HUMAN" 2 1676.8886 - 36927 22228 2 1676.895687 839.4516 Thyroid hormone receptor-associated protein 3 OS=Homo sapiens OX=9606 GN=THRAP3 PE=1 SV=2 5.93 3535.5 - 806687 - - - 4.2227 - 3.708 0.627 - 741.6 1 1 0 0.0071 15 0 0 0 - - - - - 6.8917 0.9668 221125_WJC_METTL3_EV_vs_WT_F03.22231.22231.2 1.63E-07 13/32 R.ELLESNFTLVGDDGTNK[136.11].E sp|Q96A33|CCD47_HUMAN 1 1858.904 1.06 36930 22231 2 1859.912116 930.4593 PAT complex subunit CCDC47 OS=Homo sapiens OX=9606 GN=CCDC47 PE=1 SV=1 3.92 3535.9 - 497315 - - - 542.3239 - 3.091 0.313 - 462.4 1 2 0 1.0081 17 0 0 0 9.18E+06 8.68E+06 - - - 3.8107 0.9998 221125_WJC_METTL3_EV_vs_WT_F03.22237.22237.2 7.97E-06 18-Nov R.GMQDLVEDFK.N sp|P02538|K2C6A_HUMAN 1 1180.5434 193.38 36934 22237 2 1180.545798 591.279 "Keratin, type II cytoskeletal 6A OS=Homo sapiens OX=9606 GN=KRT6A PE=1 SV=3" 4.03 3536.6 - 8.02E+06 - - - 2.0101 - 2.165 0.527 - 453 1 2 0 0.0024 10 0 0 0 1.39E+08 7.20E+05 - - - 5.0887 0.9999 221125_WJC_METTL3_EV_vs_WT_F03.22239.22239.3 4.96E-07 15/48 R.IRVESLLVTAISK.A sp|O43143|DHX15_HUMAN 1 1427.8712 1.04 36936 22239 3 1427.871944 476.9643 Pre-mRNA-splicing factor ATP-dependent RNA helicase DHX15 OS=Homo sapiens OX=9606 GN=DHX15 PE=1 SV=2 8.75 3536.7 - 2.87E+06 - - - 0.5456 - 2.805 0.52 - 439.6 1 2 1 0.0008 13 0 0 0 6.17E+07 5.96E+07 - - - 7.1337 1 221125_WJC_METTL3_EV_vs_WT_F03.22240.22240.2 1.04E-15 25/46 K.IFTASNVSSVPLPAENVTITAGQR.L "sp|Q14157|UBP2L_HUMAN,tr|F8W726|F8W726_HUMAN,tr|Q5VU77|Q5VU77_HUMAN" 3 2471.302 2.4 36937 22240 2 2471.303355 1236.6583 Ubiquitin-associated protein 2-like OS=Homo sapiens OX=9606 GN=UBAP2L PE=1 SV=2 6 3536.8 - 1.77E+06 - - - 0.5471 - 4.522 0.612 - 762 1 2 0 0.0014 24 0 0 0 2.92E+07 1.22E+07 - - - 7.2706 0.9946 221125_WJC_METTL3_EV_vs_WT_F03.22241.22241.3 2.15E-07 14/68 R.IWNLSENSTSGSTQLVLR.H "sp|Q9BZK7|TBL1R_HUMAN,tr|A0A1B0GVH3|A0A1B0GVH3_HUMAN,tr|A0A0D9SF63|A0A0D9SF63_HUMAN" 3 2004.0276 0.47 36938 22241 3 2004.043379 669.0165 F-box-like\WD repeat-containing protein TBL1XR1 OS=Homo sapiens OX=9606 GN=TBL1XR1 PE=1 SV=1 6 3536.9 - 1.73E+06 - - - 7.8642 - 2.4 0.441 - 258.1 1 2 0 0.0158 18 0 0 0 1.37E+07 2.93E+07 - - - 5.6324 0.9999 221125_WJC_METTL3_EV_vs_WT_F03.22242.22242.4 2.51E-05 17/138 K.IFTASNVSSVPLPAENVTITAGQR.L "sp|Q14157|UBP2L_HUMAN,tr|F8W726|F8W726_HUMAN,tr|Q5VU77|Q5VU77_HUMAN" 3 2471.302 1.46 36939 22242 4 2471.306011 618.8328 Ubiquitin-associated protein 2-like OS=Homo sapiens OX=9606 GN=UBAP2L PE=1 SV=2 6 3536.9 - 1.39E+06 - - - 1.6218 - 3.161 0.453 - 196.8 1 2 0 0.004 24 0 0 0 2.03E+07 1.39E+07 - - - 3.5372 1 221125_WJC_METTL3_EV_vs_WT_F03.22243.22243.2 4.76E-10 15/32 R.ELLESNFTLVGDDGTNK.E sp|Q96A33|CCD47_HUMAN 1 1850.8898 1.06 36940 22243 2 1850.887724 926.4522 PAT complex subunit CCDC47 OS=Homo sapiens OX=9606 GN=CCDC47 PE=1 SV=1 3.92 3537.1 - 883087 - - - -1.1151 - 3.29 0.556 - 631.3 1 2 0 -0.0021 17 0 0 0 9.18E+06 8.68E+06 - - - 6.0748 1 221125_WJC_METTL3_EV_vs_WT_F03.22244.22244.2 1.07E-08 15/28 K.LNPNFLQLSTGSVDK[136.11].N sp|O95628|CNOT4_HUMAN 1 1639.8661 4.6 36941 22244 2 1639.881558 820.9403 CCR4-NOT transcription complex subunit 4 OS=Homo sapiens OX=9606 GN=CNOT4 PE=1 SV=3 5.84 3537.2 - 785209 - - - 9.4349 - 2.899 0.555 - 411.2 1 2 0 0.0155 15 0 0 0 1.91E+07 4.15E+06 - - - 5.7522 1 221125_WJC_METTL3_EV_vs_WT_F03.22245.22245.2 8.50E-12 Nov-40 R.YLEVSEPQDIEC[160.03]C[160.03]GALEYYDK[136.11].A "sp|O15371|EIF3D_HUMAN,tr|B0QYA5|B0QYA5_HUMAN" 2 2588.1178 1.2 36942 22245 2 2590.125447 1295.0662 Eukaryotic translation initiation factor 3 subunit D OS=Homo sapiens OX=9606 GN=EIF3D PE=1 SV=1 3.77 3537.4 - 537814 - - - 775.7081 - 3.013 0.693 - 225.5 1 2 0 2.0076 21 0 0 0 7.49E+06 6.23E+06 - - - 6.2407 0.9883 221125_WJC_METTL3_EV_vs_WT_F03.22246.22246.2 0.00983 30-Nov R.IHFPLATYAPVISAEK[136.11].A "sp|Q6PEY2|TBA3E_HUMAN,sp|P0DPH7|TBA3C_HUMAN,sp|Q71U36|TBA1A_HUMAN,sp|P0DPH8|TBA3D_HUMAN,sp|P68366|TBA4A_HUMAN,sp|P68363|TBA1B_HUMAN,sp|Q9BQE3|TBA1C_HUMAN,tr|F8VVB9|F8VVB9_HUMAN,tr|C9JDS9|C9JDS9_HUMAN,tr|A0A1W2PQM2|A0A1W2PQM2_HUMAN,tr|F5H5D3|F5H5D3_HUMAN" 11 1763.9702 0.79 36943 22246 2 1763.982257 882.9924 Tubulin alpha-3E chain OS=Homo sapiens OX=9606 GN=TUBA3E PE=1 SV=2 6.75 3537.5 - 513376 - - - 6.8595 - 2.323 0.42 - 254.1 1 2 0 0.0121 16 0 0 0 4.14E+07 5.25E+07 - - - 4.2115 0.9995 221125_WJC_METTL3_EV_vs_WT_F03.22249.22249.3 0.00538 Nov-48 R.IR[166.11]VESLLVTAISK[136.11].A sp|O43143|DHX15_HUMAN 1 1445.8936 1.04 36944 22249 3 1445.894302 482.9718 Pre-mRNA-splicing factor ATP-dependent RNA helicase DHX15 OS=Homo sapiens OX=9606 GN=DHX15 PE=1 SV=2 8.75 3537.9 - 5.35E+06 - - - 0.4613 - 2.343 0.384 - 236.6 1 2 1 0.0007 13 0 0 0 6.17E+07 5.96E+07 - - - 5.1295 1 221125_WJC_METTL3_EV_vs_WT_F03.22250.22250.3 1.41E-09 20/80 R.YLEVSEPQDIEC[160.03]C[160.03]GALEYYDK[136.11].A "sp|O15371|EIF3D_HUMAN,tr|B0QYA5|B0QYA5_HUMAN" 2 2588.1178 1.2 36945 22250 3 2588.118604 863.7132 Eukaryotic translation initiation factor 3 subunit D OS=Homo sapiens OX=9606 GN=EIF3D PE=1 SV=1 3.77 3537.9 - 3.85E+06 - - - 0.3018 - 3.482 0.712 - 417.8 1 2 0 0.0008 21 0 0 0 4.27E+07 3.55E+07 - - - 9.469 0.9906 221125_WJC_METTL3_EV_vs_WT_F03.22251.22251.2 5.45E-05 14/30 K.LTTPTYGDLNHLVSAT.M "sp|P04350|TBB4A_HUMAN,sp|Q9BVA1|TBB2B_HUMAN,sp|P07437|TBB5_HUMAN,sp|Q13885|TBB2A_HUMAN,sp|P68371|TBB4B_HUMAN,sp|Q9BUF5|TBB6_HUMAN,tr|M0R2D3|M0R2D3_HUMAN,tr|Q5ST81|Q5ST81_HUMAN,tr|Q5JP53|Q5JP53_HUMAN,tr|K7ESM5|K7ESM5_HUMAN" 10 1701.8574 - 36946 22251 2 1701.856773 851.936 Tubulin beta-4A chain OS=Homo sapiens OX=9606 GN=TUBB4A PE=1 SV=2 5.08 3538.1 - 2.23E+06 - - - -0.3484 - 2.165 0.472 - 288.4 1 1 0 -0.0006 16 0 0 0 - - - - - 4.426 1 221125_WJC_METTL3_EV_vs_WT_F03.22252.22252.3 9.50E-06 13/68 R.IWNLSENSTSGSTQLVLR[166.11].H "sp|Q9BZK7|TBL1R_HUMAN,tr|A0A1B0GVH3|A0A1B0GVH3_HUMAN,tr|A0A0D9SF63|A0A0D9SF63_HUMAN" 3 2014.0359 1.35 36947 22252 3 2014.037552 672.3526 F-box-like\WD repeat-containing protein TBL1XR1 OS=Homo sapiens OX=9606 GN=TBL1XR1 PE=1 SV=1 6 3538.1 - 1.82E+06 - - - 0.8257 - 2.831 0.549 - 261.2 1 2 0 0.0017 18 0 0 0 1.54E+07 1.14E+07 - - - 7.2516 0.9997 221125_WJC_METTL3_EV_vs_WT_F03.22253.22253.2 0.00203 20-Nov K.LVFLGLDNAGK.T "sp|Q9NR31|SAR1A_HUMAN,sp|Q9Y6B6|SAR1B_HUMAN,tr|D6RAA2|D6RAA2_HUMAN,tr|D6RD69|D6RD69_HUMAN,tr|X1WI22|X1WI22_HUMAN,tr|Q5SQT8|Q5SQT8_HUMAN,tr|D6RDB2|D6RDB2_HUMAN" 7 1145.6445 1.09 36948 22253 2 1145.646125 573.8295 GTP-binding protein SAR1a OS=Homo sapiens OX=9606 GN=SAR1A PE=1 SV=1 5.84 3538.3 - 1.51E+06 - - - 1.4542 - 2.153 0.438 - 324.9 1 2 0 0.0017 11 0 0 0 1.33E+07 1.23E+07 - - - 4.3501 0.9981 221125_WJC_METTL3_EV_vs_WT_F03.22254.22254.2 0.00115 24-Dec R.IR[166.11]VESLLVTAISK[136.11].A sp|O43143|DHX15_HUMAN 1 1445.8936 1.11 36949 22254 2 1445.894992 723.9541 Pre-mRNA-splicing factor ATP-dependent RNA helicase DHX15 OS=Homo sapiens OX=9606 GN=DHX15 PE=1 SV=2 8.75 3538.4 - 1.45E+06 - - - 0.9385 - 2.545 0.444 - 362.9 1 2 1 0.0014 13 0 0 0 2.22E+07 1.99E+07 - - - 4.7174 0.9989 221125_WJC_METTL3_EV_vs_WT_F03.22257.22257.4 1.14E-05 16/138 K.IFTASNVSSVPLPAENVTITAGQR[166.11].L "sp|Q14157|UBP2L_HUMAN,tr|F8W726|F8W726_HUMAN,tr|Q5VU77|Q5VU77_HUMAN" 3 2481.3103 2 36952 22257 4 2481.316368 621.3348 Ubiquitin-associated protein 2-like OS=Homo sapiens OX=9606 GN=UBAP2L PE=1 SV=2 6 3538.6 - 1.19E+06 - - - 2.4564 - 2.951 0.32 - 154.2 1 2 0 0.0061 24 0 0 0 2.03E+07 1.01E+07 - - - 2.3569 1 221125_WJC_METTL3_EV_vs_WT_F03.22258.22258.2 5.34E-12 23/46 K.IFTASNVSSVPLPAENVTITAGQR[166.11].L "sp|Q14157|UBP2L_HUMAN,tr|F8W726|F8W726_HUMAN,tr|Q5VU77|Q5VU77_HUMAN" 3 2481.3103 2.4 36953 22258 2 2481.316006 1241.6624 Ubiquitin-associated protein 2-like OS=Homo sapiens OX=9606 GN=UBAP2L PE=1 SV=2 6 3538.7 - 1.02E+06 - - - 2.3105 - 4.449 0.713 - 631.5 1 2 0 0.0057 24 0 0 0 2.92E+07 1.22E+07 - - - 7.9752 1 221125_WJC_METTL3_EV_vs_WT_F03.22259.22259.3 1.15E-05 15/68 K.QFVVFEGNHYFYSPYPTK.T sp|P04843|RPN1_HUMAN 1 2222.0473 0.17 36954 22259 3 2222.045896 741.6897 Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit 1 OS=Homo sapiens OX=9606 GN=RPN1 PE=1 SV=1 6.75 3538.8 - 987190 - - - -0.6282 - 2.528 0.492 - 220.9 1 2 0 -0.0014 18 0 0 0 6.36E+07 3.73E+08 - - - 6.3343 1 221125_WJC_METTL3_EV_vs_WT_F03.22261.22261.2 3.81E-07 14/34 R.IWNLSENSTSGSTQLVLR[166.11].H "sp|Q9BZK7|TBL1R_HUMAN,tr|A0A1B0GVH3|A0A1B0GVH3_HUMAN,tr|A0A0D9SF63|A0A0D9SF63_HUMAN" 3 2014.0359 1.64 36956 22261 2 2014.039037 1008.0252 F-box-like\WD repeat-containing protein TBL1XR1 OS=Homo sapiens OX=9606 GN=TBL1XR1 PE=1 SV=1 6 3539.1 - 818559 - - - 1.563 - 3.508 0.609 - 582.9 1 2 0 0.0031 18 0 0 0 1.14E+07 6.94E+06 - - - 6.6237 1 221125_WJC_METTL3_EV_vs_WT_F03.22262.22262.2 6.86E-09 15/40 R.YLEVSEPQDIEC[160.03]C[160.03]GALEYYDK.A "sp|O15371|EIF3D_HUMAN,tr|B0QYA5|B0QYA5_HUMAN" 2 2580.1036 1.2 36957 22262 2 2580.105328 1291.0591 Eukaryotic translation initiation factor 3 subunit D OS=Homo sapiens OX=9606 GN=EIF3D PE=1 SV=1 3.77 3539.2 - 755064 - - - 0.6608 - 3.681 0.719 - 588.9 1 2 0 0.0017 21 0 0 0 7.49E+06 6.23E+06 - - - 7.5549 1 221125_WJC_METTL3_EV_vs_WT_F03.22263.22263.3 3.45E-07 22/60 R.R[166.11]LAIQLGAQALLGAAK[136.11].M "sp|Q96C36|P5CR2_HUMAN,tr|A0A087WZR9|A0A087WZR9_HUMAN,tr|A0A087WTV6|A0A087WTV6_HUMAN,tr|J3KR12|J3KR12_HUMAN" 4 1610.9951 0.78 36958 22263 3 1610.997901 538.0056 Pyrroline-5-carboxylate reductase 2 OS=Homo sapiens OX=9606 GN=PYCR2 PE=1 SV=1 11 3539.4 - 710460 - - - 1.7511 - 3.872 0.619 - 660 1 2 0 0.0028 16 0 0 0 4.73E+06 6.10E+06 - - - 8.9141 0.9791 221125_WJC_METTL3_EV_vs_WT_F03.22265.22265.3 0.00013 Dec-48 K.SFLIWVNEEDHTR[166.11].V "sp|P12532|KCRU_HUMAN,tr|F8WCN3|F8WCN3_HUMAN" 2 1654.7979 1.35 36960 22265 3 1655.793895 552.6066 "Creatine kinase U-type, mitochondrial OS=Homo sapiens OX=9606 GN=CKMT1A PE=1 SV=1" 4.65 3539.6 - 401226 - - - 601.8892 - 2.351 0.447 - 159.9 1 2 0 0.996 13 0 0 0 1.12E+07 8.34E+06 - - - 5.5654 1 221125_WJC_METTL3_EV_vs_WT_F03.22270.22270.2 8.25E-07 20-Dec K.QVEDDIQQLLK[136.11].K "sp|P35998|PRS7_HUMAN,tr|C9JX88|C9JX88_HUMAN,tr|C9JLS9|C9JLS9_HUMAN" 3 1335.7125 0.65 36963 22270 2 1335.713622 668.8635 26S proteasome regulatory subunit 7 OS=Homo sapiens OX=9606 GN=PSMC2 PE=1 SV=3 4.03 3540.2 - 3.71E+06 - - - 0.8056 - 2.637 0.563 - 533.4 1 2 0 0.0011 11 0 0 0 2.66E+07 4.12E+07 - - - 5.8221 1 221125_WJC_METTL3_EV_vs_WT_F03.22271.22271.3 1.89E-08 20/76 R.AFVHWYVGEGMEEGEFSEAR.E "sp|Q9NY65|TBA8_HUMAN,sp|Q6PEY2|TBA3E_HUMAN,sp|P0DPH7|TBA3C_HUMAN,sp|Q71U36|TBA1A_HUMAN,sp|P0DPH8|TBA3D_HUMAN,sp|P68366|TBA4A_HUMAN,sp|P68363|TBA1B_HUMAN,sp|Q9BQE3|TBA1C_HUMAN,tr|F5H5D3|F5H5D3_HUMAN,tr|C9J2C0|C9J2C0_HUMAN" 10 2329.011 0.5 36964 22271 3 2329.013126 777.3443 Tubulin alpha-8 chain OS=Homo sapiens OX=9606 GN=TUBA8 PE=1 SV=1 4.32 3540.2 - 4.53E+06 - - - 0.9201 - 3.989 0.736 - 554 1 2 0 0.0021 20 0 0 0 4.32E+07 8.66E+07 - - - 10.1016 0.9997 221125_WJC_METTL3_EV_vs_WT_F03.22272.22272.3 3.79E-06 14/48 K.HELLQPFNVLYEK[136.11].E sp|Q9UQ80|PA2G4_HUMAN 1 1636.8704 1.07 36965 22272 3 1636.868676 546.6308 Proliferation-associated protein 2G4 OS=Homo sapiens OX=9606 GN=PA2G4 PE=1 SV=3 5.4 3540.3 - 6.11E+06 - - - -1.0795 - 2.721 0.28 - 449.5 1 2 0 -0.0018 13 0 0 0 1.35E+08 1.26E+08 - - - 4.3752 0.9805 221125_WJC_METTL3_EV_vs_WT_F03.22274.22274.3 1.67E-08 14/72 R.IPDHLTSGEGFDSFSSLVK[136.11].S sp|Q5T3J3|LRIF1_HUMAN 1 2043.004 1.54 36967 22274 3 2043.996162 682.0086 Ligand-dependent nuclear receptor-interacting factor 1 OS=Homo sapiens OX=9606 GN=LRIF1 PE=1 SV=1 4.54 3540.4 - 2.39E+06 - - - 485.6212 - 2.605 0.528 - 131.3 1 2 0 0.9921 19 0 0 0 3.09E+07 2.01E+07 - - - 6.5041 1 221125_WJC_METTL3_EV_vs_WT_F03.22282.22282.2 3.22E-06 13/24 K.NVVTTLLNAGGEK.T "sp|Q7Z589|EMSY_HUMAN,tr|E9PMC9|E9PMC9_HUMAN" 2 1314.7143 0.67 36975 22282 2 1314.720787 658.3644 BRCA2-interacting transcriptional repressor EMSY OS=Homo sapiens OX=9606 GN=EMSY PE=1 SV=2 6 3541.2 - 1.15E+06 - - - 4.9113 - 2.588 0.6 - 440.4 1 2 0 0.0065 13 0 0 0 7.97E+06 1.19E+07 - - - 5.911 1 221125_WJC_METTL3_EV_vs_WT_F03.22283.22283.3 1.43E-05 15/48 K.SFLIWVNEEDHTR.V "sp|P12532|KCRU_HUMAN,tr|F8WCN3|F8WCN3_HUMAN" 2 1644.7896 1.38 36976 22283 3 1644.791551 549.2705 "Creatine kinase U-type, mitochondrial OS=Homo sapiens OX=9606 GN=CKMT1A PE=1 SV=1" 4.65 3541.3 - 995365 - - - 1.174 - 3.066 0.593 - 312.5 1 2 0 0.0019 13 0 0 0 1.15E+07 8.34E+06 - - - 8.1885 0.9999 221125_WJC_METTL3_EV_vs_WT_F03.22293.22293.3 3.63E-06 19/76 K.AAYPDLENPPLLVTPSQQAK.F "sp|P54136|SYRC_HUMAN,tr|E5RJM9|E5RJM9_HUMAN" 2 2151.1212 1.37 36984 22293 3 2151.127876 718.0477 "Arginine--tRNA ligase, cytoplasmic OS=Homo sapiens OX=9606 GN=RARS1 PE=1 SV=2" 4.37 3542.5 - 955690 - - - 3.1105 - 3.228 0.443 - 305.5 1 2 0 0.0067 20 0 0 0 6.64E+06 4.85E+06 - - - 6.3201 1 221125_WJC_METTL3_EV_vs_WT_F03.22295.22295.3 7.31E-11 26/100 R.LPTGYYFGASAGTGDLSDNHDIISMK.L "sp|Q12907|LMAN2_HUMAN,tr|D6RBV2|D6RBV2_HUMAN,tr|D6RDX1|D6RDX1_HUMAN" 3 2729.2643 0.92 36986 22295 3 2729.268437 910.762 Vesicular integral-membrane protein VIP36 OS=Homo sapiens OX=9606 GN=LMAN2 PE=1 SV=1 4.41 3542.8 - 918778 - - - 1.5169 - 4.88 0.683 - 527.8 1 2 0 0.0041 26 0 0 0 3.41E+06 3.70E+06 - - - 9.8005 0.9999 221125_WJC_METTL3_EV_vs_WT_F03.22299.22299.2 9.88E-06 20-Nov R.NPEAALSPTFR[166.11].S "sp|Q86U44|MTA70_HUMAN,tr|B4E349|B4E349_HUMAN,tr|F5H6D8|F5H6D8_HUMAN,tr|B4DTN4|B4DTN4_HUMAN" 4 1211.6174 0.001 36990 22299 2 1211.617979 606.816 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 6 3543.3 - 745747 - - - 0.4721 - 2.393 0.446 - 297.9 1 2 0 0.0006 11 0 0 0 0.00E+00 7.86E+06 - - - 4.6954 0.9994 221125_WJC_METTL3_EV_vs_WT_F03.22302.22302.2 8.28E-06 30-Dec R.IHFPLATYAPVISAEK.A "sp|Q6PEY2|TBA3E_HUMAN,sp|P0DPH7|TBA3C_HUMAN,sp|Q71U36|TBA1A_HUMAN,sp|P0DPH8|TBA3D_HUMAN,sp|P68366|TBA4A_HUMAN,sp|P68363|TBA1B_HUMAN,sp|Q9BQE3|TBA1C_HUMAN,tr|F8VVB9|F8VVB9_HUMAN,tr|C9JDS9|C9JDS9_HUMAN,tr|A0A1W2PQM2|A0A1W2PQM2_HUMAN,tr|F5H5D3|F5H5D3_HUMAN" 11 1755.956 0.71 36993 22302 2 1755.961817 878.9853 Tubulin alpha-3E chain OS=Homo sapiens OX=9606 GN=TUBA3E PE=1 SV=2 6.75 3543.7 - 336358 - - - 3.3372 - 2.526 0.544 - 354.3 1 2 0 0.0059 16 0 0 0 1.93E+07 2.71E+07 - - - 5.3353 0.9996 221125_WJC_METTL3_EV_vs_WT_F03.22305.22305.2 1.58E-05 26-Dec K.LQQENLQIFTQLQK[136.11].L "sp|Q8TD19|NEK9_HUMAN,tr|A0A7I2V5R1|A0A7I2V5R1_HUMAN,tr|A0A7I2V454|A0A7I2V454_HUMAN" 3 1737.9505 -1 36996 22305 2 1737.954872 869.9825 Serine\threonine-protein kinase Nek9 OS=Homo sapiens OX=9606 GN=NEK9 PE=1 SV=2 6 3544.1 - 208775 - - - 2.5242 - 2.472 0.456 - 523.4 1 2 0 0.0044 14 0 0 0 0.00E+00 0.00E+00 - - - 4.6788 0.9998 221125_WJC_METTL3_EV_vs_WT_F03.22310.22310.3 2.37E-05 13/52 R.GVDKEPLNLFYIER.D sp|Q14574|DSC3_HUMAN 1 1691.8883 184.35 36999 22310 3 1691.891417 564.97 Desmocollin-3 OS=Homo sapiens OX=9606 GN=DSC3 PE=1 SV=3 4.68 3544.6 - 2.57E+06 - - - 1.8589 - 2.76 0.509 - 267.6 1 2 1 0.0031 14 0 0 0 5.91E+07 3.21E+05 - - - 6.912 0.9998 221125_WJC_METTL3_EV_vs_WT_F03.22311.22311.2 0.000905 18-Nov R.NLDFQDVLDK.L sp|Q9Y3I0|RTCB_HUMAN 1 1205.5928 1.2 37000 22311 2 1205.593418 603.8037 RNA-splicing ligase RtcB homolog OS=Homo sapiens OX=9606 GN=RTCB PE=1 SV=1 3.93 3544.7 - 1.43E+06 - - - 0.4977 - 2.22 0.43 - 366.2 1 2 0 0.0006 10 0 0 0 1.51E+07 1.26E+07 - - - 4.4429 0.9999 221125_WJC_METTL3_EV_vs_WT_F03.22312.22312.3 4.09E-05 14/76 K.GVTIASGGVLPNIHPELLAK[136.11].K "sp|O75367|H2AY_HUMAN,tr|D6RCF2|D6RCF2_HUMAN" 2 1993.1452 1.84 37001 22312 3 1993.1477 665.389 Core histone macro-H2A.1 OS=Homo sapiens OX=9606 GN=MACROH2A1 PE=1 SV=4 6.75 3544.8 - 1.60E+06 - - - 1.2734 - 2.344 0.41 - 215.9 1 2 0 0.0025 20 0 0 0 3.68E+07 2.00E+07 - - - 5.177 1 221125_WJC_METTL3_EV_vs_WT_F03.22313.22313.2 1.17E-09 13/26 R.DVDFEGTDEPIFGK.K "sp|P42285|MTREX_HUMAN,tr|H0Y8U3|H0Y8U3_HUMAN" 2 1567.7042 999 37002 22313 2 1567.708138 784.8594 Exosome RNA helicase MTR4 OS=Homo sapiens OX=9606 GN=MTREX PE=1 SV=3 3.77 3544.9 - 1.24E+06 - - - 2.4998 - 2.854 0.703 - 470.8 1 2 0 0.0039 14 0 0 0 1.96E+07 0.00E+00 - - - 6.8638 1 221125_WJC_METTL3_EV_vs_WT_F03.22315.22315.2 2.21E-11 15/28 R.QNLDYNYYSVPIQIK.D sp|Q08554|DSC1_HUMAN 1 1856.9309 999 37004 22315 2 1856.932284 929.4727 Desmocollin-1 OS=Homo sapiens OX=9606 GN=DSC1 PE=1 SV=2 5.83 3545.1 - 908050 - - - 0.7642 - 2.797 0.647 - 501.6 1 2 0 0.0014 15 0 0 0 6.88E+06 0.00E+00 - - - 6.348 0.9999 221125_WJC_METTL3_EV_vs_WT_F03.22317.22317.3 0.025 14/48 R.KFLETVELQISLK.N sp|P62906|RL10A_HUMAN 1 1546.897 1.17 37006 22317 3 1546.89599 516.6396 60S ribosomal protein L10a OS=Homo sapiens OX=9606 GN=RPL10A PE=1 SV=2 6.14 3545.4 - 735510 - - - -0.6827 - 2.861 0.391 - 450.3 1 2 0 -0.0011 13 0 0 0 6.97E+06 5.96E+06 - - - 5.749 0.9999 221125_WJC_METTL3_EV_vs_WT_F03.22318.22318.3 13.2 14/48 R.K[136.11]FLETVELQISLK[136.11].N sp|P62906|RL10A_HUMAN 1 1562.9254 1.17 37007 22318 3 1562.92722 521.9824 60S ribosomal protein L10a OS=Homo sapiens OX=9606 GN=RPL10A PE=1 SV=2 6.14 3545.5 - 683063 - - - 1.1357 - 2.871 0.333 - 458.3 1 2 0 0.0018 13 0 0 0 6.97E+06 5.96E+06 - - - 5.1116 0.9999 221125_WJC_METTL3_EV_vs_WT_F03.22323.22323.3 0.000361 Dec-52 K.AFDLIVDRPVTLVR.E "sp|O96000|NDUBA_HUMAN,tr|H3BPJ9|H3BPJ9_HUMAN,tr|H3BV16|H3BV16_HUMAN" 3 1612.9301 1.85 37012 22323 3 1612.931318 538.6506 NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 10 OS=Homo sapiens OX=9606 GN=NDUFB10 PE=1 SV=3 6.01 3546.1 - 380545 - - - 0.7694 - 2.297 0.386 - 131.8 1 2 0 0.0012 14 0 0 0 2.92E+06 1.58E+06 - - - 5.0532 1 221125_WJC_METTL3_EV_vs_WT_F03.22327.22327.3 1.30E-06 19/72 K.ETLLNGVGYLHEGLSPMER.R sp|O75643|U520_HUMAN 1 2114.0466 0.12 37014 22327 3 2114.048403 705.6895 U5 small nuclear ribonucleoprotein 200 kDa helicase OS=Homo sapiens OX=9606 GN=SNRNP200 PE=1 SV=2 4.75 3546.6 - 2.97E+06 - - - 0.8339 - 3.29 0.541 - 440 1 2 0 0.0018 19 0 0 0 2.73E+07 2.28E+08 - - - 7.4969 0.9998 221125_WJC_METTL3_EV_vs_WT_F03.22328.22328.2 5.46E-07 13/24 R.DEPTGEVLSLVGK[136.11].L "sp|O75643|U520_HUMAN,tr|A0A494C1A5|A0A494C1A5_HUMAN" 2 1350.7122 2.32 37015 22328 2 1350.714843 676.3634 U5 small nuclear ribonucleoprotein 200 kDa helicase OS=Homo sapiens OX=9606 GN=SNRNP200 PE=1 SV=2 4.14 3546.7 - 1.99E+06 - - - 1.9486 - 2.623 0.567 - 701.4 1 2 0 0.0026 13 0 0 0 1.94E+08 8.36E+07 - - - 5.703 0.9983 221125_WJC_METTL3_EV_vs_WT_F03.22332.22332.3 0.00651 18/60 R.DGLK[136.11]LMLLLEVISGER[166.11].L "sp|O43707|ACTN4_HUMAN,sp|P12814|ACTN1_HUMAN,tr|A0A804HK61|A0A804HK61_HUMAN,tr|A0A804HIN7|A0A804HIN7_HUMAN,tr|G3V5M4|G3V5M4_HUMAN,tr|A0A804HLF4|A0A804HLF4_HUMAN,tr|A0A804HIY0|A0A804HIY0_HUMAN,tr|A0A7I2V4Y4|A0A7I2V4Y4_HUMAN,tr|A0A804HII9|A0A804HII9_HUMAN,tr|A0A804HJQ9|A0A804HJQ9_HUMAN,tr|F5GXS2|F5GXS2_HUMAN,tr|A0A804HKE2|A0A804HKE2_HUMAN,tr|G3V2N5|G3V2N5_HUMAN,tr|A0A804HLD0|A0A804HLD0_HUMAN,tr|H7C144|H7C144_HUMAN" 15 1803.0295 0 37019 22332 3 1803.034794 602.0171 Alpha-actinin-4 OS=Homo sapiens OX=9606 GN=ACTN4 PE=1 SV=2 4.68 3547 - 2.26E+06 - - - 2.9489 - 2.505 0.385 - 388.5 1 2 1 0.0053 16 0 0 0 1.61E+07 3.43E+09 - - - 5.1871 1 221125_WJC_METTL3_EV_vs_WT_F03.22333.22333.2 3.86E-06 14/26 K.NIYVLQELDNPGAK[136.11].R "sp|P12956|XRCC6_HUMAN,tr|B1AHC9|B1AHC9_HUMAN" 2 1580.829 1.19 37020 22333 2 1580.827201 791.4218 X-ray repair cross-complementing protein 6 OS=Homo sapiens OX=9606 GN=XRCC6 PE=1 SV=2 4.37 3547.1 - 1.74E+06 - - - -1.1203 - 2.845 0.571 - 610.9 1 2 0 -0.0018 14 0 0 0 2.78E+07 2.33E+07 - - - 5.8816 1 221125_WJC_METTL3_EV_vs_WT_F03.22334.22334.2 1.04E-09 20/32 R.DQSAVVVQGLPEGVAFK.H "sp|P78347|GTF2I_HUMAN,tr|A0A494C1K3|A0A494C1K3_HUMAN" 2 1742.9203 1.56 37021 22334 2 1742.921014 872.4674 General transcription factor II-I OS=Homo sapiens OX=9606 GN=GTF2I PE=1 SV=2 4.37 3547.2 - 1.28E+06 - - - 0.4097 - 3.684 0.546 - 1303.6 1 2 0 0.0007 17 0 0 0 1.10E+09 7.05E+08 - - - 6.2795 0.9997 221125_WJC_METTL3_EV_vs_WT_F03.22335.22335.2 4.26E-05 17/28 K.ELGSLPLPLSTSEQR.Q "sp|Q86Y82|STX12_HUMAN,tr|B1AJQ6|B1AJQ6_HUMAN" 2 1625.8625 0.77 37022 22335 2 1625.866735 813.9385 Syntaxin-12 OS=Homo sapiens OX=9606 GN=STX12 PE=1 SV=1 4.53 3547.4 - 1.13E+06 - - - 2.6349 - 2.917 0.541 - 605.5 1 2 0 0.0043 15 0 0 0 1.73E+07 2.23E+07 - - - 5.6675 1 221125_WJC_METTL3_EV_vs_WT_F03.22336.22336.4 4.56E-08 20/90 R.DYLHLPPEIVPATLRR.S "sp|P46783|RS10_HUMAN,tr|A0A2R8Y6L3|A0A2R8Y6L3_HUMAN,tr|F6U211|F6U211_HUMAN,tr|A0A1W2PQS6|A0A1W2PQS6_HUMAN,tr|A0A2R8YFH6|A0A2R8YFH6_HUMAN,tr|A0A2R8Y7H1|A0A2R8Y7H1_HUMAN,tr|S4R435|S4R435_HUMAN" 7 1889.0523 1.04 37023 22336 4 1889.054744 473.2704 40S ribosomal protein S10 OS=Homo sapiens OX=9606 GN=RPS10 PE=1 SV=1 6.75 3547.5 - 1.11E+06 - - - 1.2848 - 2.933 0.527 - 315.3 1 2 0 0.0024 16 0 0 0 1.42E+07 1.37E+07 - - - 4.1914 0.9977 221125_WJC_METTL3_EV_vs_WT_F03.22337.22337.3 0.0298 Dec-52 K.NIYVLQELDNPGAK.R "sp|P12956|XRCC6_HUMAN,tr|B1AHC9|B1AHC9_HUMAN" 2 1572.8148 1.75 37024 22337 3 1572.814042 525.2789 X-ray repair cross-complementing protein 6 OS=Homo sapiens OX=9606 GN=XRCC6 PE=1 SV=2 4.37 3547.6 - 976458 - - - -0.4641 - 1.827 0.233 - 168.2 1 2 0 -0.0007 14 0 0 0 9.51E+06 5.44E+06 - - - 2.7391 1 221125_WJC_METTL3_EV_vs_WT_F03.22338.22338.2 4.77E-08 20/32 R.DQSAVVVQGLPEGVAFK[136.11].H "sp|P78347|GTF2I_HUMAN,tr|A0A494C1K3|A0A494C1K3_HUMAN" 2 1750.9345 1.56 37025 22338 2 1750.942547 876.4745 General transcription factor II-I OS=Homo sapiens OX=9606 GN=GTF2I PE=1 SV=2 4.37 3547.7 - 824614 - - - 4.5958 - 3.64 0.584 - 1117.9 1 2 0 0.008 17 0 0 0 1.10E+09 7.05E+08 - - - 6.5283 1 221125_WJC_METTL3_EV_vs_WT_F03.22339.22339.3 6.50E-11 27/76 R.KGLPLGSAVSSPVLFSPVGR.R sp|Q8WUM0|NU133_HUMAN 1 1967.1204 0.67 37026 22339 3 1967.122466 656.7141 Nuclear pore complex protein Nup133 OS=Homo sapiens OX=9606 GN=NUP133 PE=1 SV=2 11 3547.8 - 752144 - - - 1.0518 - 3.822 0.588 - 782.9 1 2 0 0.0021 20 0 0 0 1.67E+07 2.49E+07 - - - 8.3478 0.9996 221125_WJC_METTL3_EV_vs_WT_F03.22340.22340.2 1.13E-05 14/28 K.SLDIQVPNFPADETK.G "sp|P47897|SYQ_HUMAN,tr|B4DDN1|B4DDN1_HUMAN,tr|H7C0R3|H7C0R3_HUMAN,tr|A0A0U1RQX5|A0A0U1RQX5_HUMAN,tr|A0A1B0GVU9|A0A1B0GVU9_HUMAN,tr|A0A0U1RRC8|A0A0U1RRC8_HUMAN" 6 1672.8308 1.94 37027 22340 2 1672.835451 837.4227 Glutamine--tRNA ligase OS=Homo sapiens OX=9606 GN=QARS1 PE=1 SV=1 4.03 3548 - 548364 - - - 2.7708 - 2.573 0.552 - 535.9 1 2 0 0.0046 15 0 0 0 3.86E+07 1.99E+07 - - - 5.4401 0.9999 221125_WJC_METTL3_EV_vs_WT_F03.22341.22341.3 0.0472 15/40 K.SQLDIIIHSLK.K sp|P13010|XRCC5_HUMAN 1 1265.7343 1.01 37028 22341 3 1265.732749 422.9187 X-ray repair cross-complementing protein 5 OS=Homo sapiens OX=9606 GN=XRCC5 PE=1 SV=3 6.46 3548.1 - 351561 - - - -1.2546 - 2.726 0.357 - 389.1 1 2 0 -0.0016 11 0 0 0 1.64E+07 1.62E+07 - - - 5.3686 0.9995 221125_WJC_METTL3_EV_vs_WT_F03.22342.22342.3 1.79E-05 Dec-44 K.VWDLFPEADKVR.T "sp|Q99613|EIF3C_HUMAN,sp|B5ME19|EIFCL_HUMAN" 2 1473.7616 0.6 37029 22342 3 1473.764336 492.2611 Eukaryotic translation initiation factor 3 subunit C OS=Homo sapiens OX=9606 GN=EIF3C PE=1 SV=1 4.56 3548.2 - 307199 - - - 1.8463 - 2.009 0.467 - 152.4 1 2 1 0.0027 12 0 0 0 7.08E+06 1.18E+07 - - - 5.6796 1 221125_WJC_METTL3_EV_vs_WT_F03.22343.22343.2 1.91E-08 14/30 R.LQQTQNQVDEVVDIMR.V sp|Q15836|VAMP3_HUMAN 1 1914.9469 0.97 37030 22343 2 1914.95398 958.4807 Vesicle-associated membrane protein 3 OS=Homo sapiens OX=9606 GN=VAMP3 PE=1 SV=3 4.03 3548.4 - 278924 - - - 3.6837 - 3.144 0.635 - 707.4 1 2 0 0.0071 16 0 0 0 8.31E+06 8.57E+06 - - - 6.5451 1 221125_WJC_METTL3_EV_vs_WT_F03.22349.22349.3 5.25E-08 19/64 R.DQSAVVVQGLPEGVAFK.H "sp|P78347|GTF2I_HUMAN,tr|A0A494C1K3|A0A494C1K3_HUMAN" 2 1742.9203 1.55 37034 22349 3 1742.92172 581.9807 General transcription factor II-I OS=Homo sapiens OX=9606 GN=GTF2I PE=1 SV=2 4.37 3548.9 - 4.07E+06 - - - 0.8147 - 3.499 0.572 - 445.9 1 2 0 0.0014 17 0 0 0 4.13E+08 2.65E+08 - - - 8.081 0.9998 221125_WJC_METTL3_EV_vs_WT_F03.22352.22352.3 0.0102 14/64 R.VNIHGIFSVASASVIEK[136.11].Q "sp|O95757|HS74L_HUMAN,tr|D6RJ96|D6RJ96_HUMAN,tr|E9PDE8|E9PDE8_HUMAN" 3 1777.9818 0.37 37037 22352 3 1777.984926 593.6679 Heat shock 70 kDa protein 4L OS=Homo sapiens OX=9606 GN=HSPA4L PE=1 SV=3 6.72 3549.1 - 1.92E+06 - - - 1.7666 - 2.82 0.347 - 263 1 2 0 0.0031 17 0 0 0 2.42E+07 6.52E+07 - - - 5.0269 1 221125_WJC_METTL3_EV_vs_WT_F03.22354.22354.3 1.06E-06 17/68 K.IEANAGQLYLTGVVVLHK.D sp|O43395|PRPF3_HUMAN 1 1924.0782 2.89 37039 22354 3 1924.079963 642.3667 U4\U6 small nuclear ribonucleoprotein Prp3 OS=Homo sapiens OX=9606 GN=PRPF3 PE=1 SV=2 6.75 3549.3 - 1.52E+06 - - - 0.9173 - 3.101 0.588 - 369.1 1 2 0 0.0018 18 0 0 0 3.03E+07 1.05E+07 - - - 7.9132 1 221125_WJC_METTL3_EV_vs_WT_F03.22355.22355.3 7.66E-06 22/64 R.WQVVDTPGILDHPLEDR.N sp|Q9BZE4|GTPB4_HUMAN 1 1988.9956 1.06 37040 22355 3 1988.995388 664.0058 GTP-binding protein 4 OS=Homo sapiens OX=9606 GN=GTPBP4 PE=1 SV=3 4.22 3549.4 - 1.32E+06 - - - -0.1016 - 3.505 0.496 - 595.5 1 2 0 -0.0002 17 0 0 0 9.46E+06 8.89E+06 - - - 7.2383 0.9974 221125_WJC_METTL3_EV_vs_WT_F03.22356.22356.3 0.0175 Oct-40 R.FKDIFQEIYDK.Q sp|O75874|IDHC_HUMAN 1 1444.7238 1.87 37041 22356 3 1444.725276 482.5819 Isocitrate dehydrogenase [NADP] cytoplasmic OS=Homo sapiens OX=9606 GN=IDH1 PE=1 SV=2 4.56 3549.5 - 1.30E+06 - - - 0.9995 - 1.987 0.297 - 107.7 1 2 1 0.0014 11 0 0 0 1.26E+07 6.77E+06 - - - 3.8014 0.9998 221125_WJC_METTL3_EV_vs_WT_F03.22357.22357.3 0.00143 17/40 K.SQLDIIIHSLK[136.11].K sp|P13010|XRCC5_HUMAN 1 1273.7485 1.01 37042 22357 3 1273.747486 425.5901 X-ray repair cross-complementing protein 5 OS=Homo sapiens OX=9606 GN=XRCC5 PE=1 SV=3 6.46 3549.6 - 1.28E+06 - - - -0.8251 - 2.715 0.305 - 532.4 1 2 0 -0.0011 11 0 0 0 1.64E+07 1.62E+07 - - - 4.7776 0.9993 221125_WJC_METTL3_EV_vs_WT_F03.22358.22358.2 0.000982 Oct-34 R.GIPGLDVEDDEEGGGGAP.- "sp|Q9ULX6|AKP8L_HUMAN,tr|A0A7P0TAE3|A0A7P0TAE3_HUMAN" 2 1682.7271 - 37043 22358 2 1682.726413 842.3708 A-kinase anchor protein 8-like OS=Homo sapiens OX=9606 GN=AKAP8L PE=1 SV=4 3.29 3549.8 - 1.27E+06 - - - -0.4314 - 1.673 0.321 - 121.1 1 2 0 -0.0007 18 0 0 0 - - - - - 2.6769 0.9999 221125_WJC_METTL3_EV_vs_WT_F03.22359.22359.3 5.35E-06 18/64 R.WQVVDTPGILDHPLEDR[166.11].N sp|Q9BZE4|GTPB4_HUMAN 1 1999.0039 1.06 37044 22359 3 1999.007834 667.3419 GTP-binding protein 4 OS=Homo sapiens OX=9606 GN=GTPBP4 PE=1 SV=3 4.22 3549.9 - 1.24E+06 - - - 1.988 - 3.413 0.375 - 347.5 1 2 0 0.004 17 0 0 0 9.46E+06 8.89E+06 - - - 5.821 0.9999 221125_WJC_METTL3_EV_vs_WT_F03.22361.22361.3 4.64E-05 22/64 K.GIEILTDMSR[166.11]PVELSDR[166.11].E sp|P50991|TCPD_HUMAN 1 1949.9995 0.29 37046 22361 3 1950.005703 651.0071 T-complex protein 1 subunit delta OS=Homo sapiens OX=9606 GN=CCT4 PE=1 SV=4 4.32 3550.1 - 904511 - - - 3.1723 - 3.149 0.452 - 764.9 1 2 0 0.0062 17 0 0 0 9.42E+07 3.21E+08 - - - 6.4755 0.9995 221125_WJC_METTL3_EV_vs_WT_F03.22362.22362.3 3.91E-06 16/56 R.IAK[136.11]EEIFGPVQPLFK[136.11].F sp|P30837|AL1B1_HUMAN 1 1730.9942 1.4 37047 22362 3 1730.997676 578.0053 "Aldehyde dehydrogenase X, mitochondrial OS=Homo sapiens OX=9606 GN=ALDH1B1 PE=1 SV=3" 6.14 3550.2 - 832659 - - - 2.0116 - 2.541 0.438 - 204.5 1 2 1 0.0035 15 0 0 0 1.61E+07 1.15E+07 - - - 5.8557 0.9928 221125_WJC_METTL3_EV_vs_WT_F03.22367.22367.2 0.0477 30-Nov R.DGLK[136.11]LMLLLEVISGER[166.11].L "sp|O43707|ACTN4_HUMAN,sp|P12814|ACTN1_HUMAN,tr|A0A804HK61|A0A804HK61_HUMAN,tr|A0A804HIN7|A0A804HIN7_HUMAN,tr|G3V5M4|G3V5M4_HUMAN,tr|A0A804HLF4|A0A804HLF4_HUMAN,tr|A0A804HIY0|A0A804HIY0_HUMAN,tr|A0A7I2V4Y4|A0A7I2V4Y4_HUMAN,tr|A0A804HII9|A0A804HII9_HUMAN,tr|A0A804HJQ9|A0A804HJQ9_HUMAN,tr|F5GXS2|F5GXS2_HUMAN,tr|A0A804HKE2|A0A804HKE2_HUMAN,tr|G3V2N5|G3V2N5_HUMAN,tr|A0A804HLD0|A0A804HLD0_HUMAN,tr|H7C144|H7C144_HUMAN" 15 1803.0295 0.001 37050 22367 2 1803.029417 902.522 Alpha-actinin-4 OS=Homo sapiens OX=9606 GN=ACTN4 PE=1 SV=2 4.68 3550.7 - 5.42E+06 - - - -0.0333 - 1.936 0.285 - 315.6 1 2 1 -0.0001 16 0 0 0 0.00E+00 2.73E+08 - - - 2.7702 0.9895 221125_WJC_METTL3_EV_vs_WT_F03.22371.22371.3 0.00976 Aug-40 R.FK[136.11]DIFQEIYDK[136.11].Q sp|O75874|IDHC_HUMAN 1 1460.7522 1.85 37054 22371 3 1460.75064 487.9247 Isocitrate dehydrogenase [NADP] cytoplasmic OS=Homo sapiens OX=9606 GN=IDH1 PE=1 SV=2 4.56 3551.2 - 660223 - - - -1.0898 - 1.773 0.233 - 69.5 1 2 1 -0.0016 11 0 0 0 1.25E+07 6.77E+06 - - - 2.7641 1 221125_WJC_METTL3_EV_vs_WT_F03.22372.22372.2 9.27E-06 16/30 R.LQQTQNQVDEVVDIMR[166.11].V sp|Q15836|VAMP3_HUMAN 1 1924.9552 1.05 37055 22372 2 1924.95325 963.4849 Vesicle-associated membrane protein 3 OS=Homo sapiens OX=9606 GN=VAMP3 PE=1 SV=3 4.03 3551.4 - 602128 - - - -1.0109 - 3.455 0.578 - 1111.8 1 2 0 -0.0019 16 0 0 0 8.31E+06 7.95E+06 - - - 6.3577 0.9382 221125_WJC_METTL3_EV_vs_WT_F03.22373.22373.3 0.691 Nov-40 R.QFLFR[166.11]PWDVTK[136.11].L sp|P22314|UBA1_HUMAN 1 1453.7837 0.77 37056 22373 3 1453.78341 485.6018 Ubiquitin-like modifier-activating enzyme 1 OS=Homo sapiens OX=9606 GN=UBA1 PE=1 SV=3 8.75 3551.5 - 473318 - - - -0.1933 - 1.663 0.067 - 149.5 1 2 0 -0.0003 11 0 0 0 7.30E+06 9.44E+06 - - - 0.7318 1 221125_WJC_METTL3_EV_vs_WT_F03.22374.22374.2 1.75E-09 14/36 R.VADGGGAGGTFQPYLDTLR[166.11].Q "sp|Q9Y5M8|SRPRB_HUMAN,tr|C9J5Z8|C9J5Z8_HUMAN" 2 1903.9304 1.88 37057 22374 2 1903.929661 952.9725 Signal recognition particle receptor subunit beta OS=Homo sapiens OX=9606 GN=SRPRB PE=1 SV=3 4.21 3551.6 - 429828 - - - -0.3677 - 3.21 0.677 - 348.2 1 2 0 -0.0007 19 0 0 0 8.75E+06 4.65E+06 - - - 6.9084 0.9988 221125_WJC_METTL3_EV_vs_WT_F03.22375.22375.2 0.00025 30-Dec R.LQEELSQAESTIDELK.E "sp|Q14203|DCTN1_HUMAN,tr|A0A804CDA6|A0A804CDA6_HUMAN,tr|E7EX90|E7EX90_HUMAN,tr|A0A7P0Z4C3|A0A7P0Z4C3_HUMAN,tr|Q6AWB1|Q6AWB1_HUMAN" 5 1831.9051 9.4 37058 22375 2 1831.90733 916.9598 Dynactin subunit 1 OS=Homo sapiens OX=9606 GN=DCTN1 PE=1 SV=3 3.91 3551.8 - 377288 - - - 1.2151 - 2.083 0.231 - 178.3 1 2 0 0.0022 16 0 0 0 4.09E+06 4.35E+05 - - - 2.5506 0.999 221125_WJC_METTL3_EV_vs_WT_F03.22377.22377.3 2.81E-09 16/76 K.GNPQGFNQGLDC[160.03]DVIVAEVR[166.11].S sp|Q86U44|MTA70_HUMAN 1 2197.0461 0.01 37059 22377 3 2198.044274 733.356 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 4.03 3552 - 2.15E+06 - - - 454.3091 - 2.917 0.6 - 298 1 2 0 0.9981 20 0 0 0 2.97E+05 2.26E+07 - - - 7.5501 1 221125_WJC_METTL3_EV_vs_WT_F03.22379.22379.3 3.52E-09 17/68 R.INPYMSSPC[160.03]HIEMILTEK.E "sp|P18621|RL17_HUMAN,tr|J3QLC8|J3QLC8_HUMAN,tr|J3QQT2|J3QQT2_HUMAN,tr|A0A0A0MRF8|A0A0A0MRF8_HUMAN,tr|J3KRX5|J3KRX5_HUMAN,tr|A0A087WXM6|A0A087WXM6_HUMAN,tr|A0A0A6YYL6|A0A0A6YYL6_HUMAN" 7 2162.021 0.78 37060 22379 3 2162.021603 721.6809 60S ribosomal protein L17 OS=Homo sapiens OX=9606 GN=RPL17 PE=1 SV=3 5.4 3552.2 - 3.75E+06 - - - 0.2701 - 3.398 0.643 - 346.3 1 2 0 0.0006 18 0 0 0 8.81E+07 1.13E+08 - - - 8.7545 1 221125_WJC_METTL3_EV_vs_WT_F03.22381.22381.3 2.11E-12 26/76 R.SLQTGFAIGVQQLHPTLIQR.T "sp|Q9H0Z9|RBM38_HUMAN,tr|A6NG75|A6NG75_HUMAN,tr|F6VZ39|F6VZ39_HUMAN" 3 2206.2222 3.74 37062 22381 3 2206.223291 736.4147 RNA-binding protein 38 OS=Homo sapiens OX=9606 GN=RBM38 PE=1 SV=2 9.49 3552.3 - 4.17E+06 - - - 0.4782 - 3.993 0.674 - 805.8 1 2 0 0.0011 20 0 0 0 2.02E+07 5.40E+06 - - - 9.4131 0.9999 221125_WJC_METTL3_EV_vs_WT_F03.22382.22382.3 0.503 16/64 K.GIEILTDMSRPVELSDR.E sp|P50991|TCPD_HUMAN 1 1929.983 0.3 37063 22382 3 1929.982469 644.3349 T-complex protein 1 subunit delta OS=Homo sapiens OX=9606 GN=CCT4 PE=1 SV=4 4.32 3552.3 - 3.03E+06 - - - -0.2632 - 2.783 0.359 - 300.1 1 2 0 -0.0005 17 0 0 0 9.78E+07 3.24E+08 - - - 5.1281 0.9999 221125_WJC_METTL3_EV_vs_WT_F03.22385.22385.2 2.94E-05 15/22 K.SLSLGEVLDGDR[166.11].M "sp|O15321|TM9S1_HUMAN,tr|E9PJC4|E9PJC4_HUMAN,tr|E9PSI1|E9PSI1_HUMAN,tr|E9PL78|E9PL78_HUMAN,tr|E9PJM1|E9PJM1_HUMAN,tr|E9PS99|E9PS99_HUMAN,tr|E9PQY7|E9PQY7_HUMAN,tr|E9PMQ9|E9PMQ9_HUMAN" 8 1269.644 1.59 37066 22385 2 1269.644406 635.8293 Transmembrane 9 superfamily member 1 OS=Homo sapiens OX=9606 GN=TM9SF1 PE=2 SV=2 4.03 3552.6 - 2.31E+06 - - - 0.308 - 2.625 0.506 - 681.6 1 2 0 0.0004 12 0 0 0 3.17E+07 2.00E+07 - - - 5.3175 1 221125_WJC_METTL3_EV_vs_WT_F03.22386.22386.2 1.60E-09 17/30 K.SYELPDGQVITIGNER.F "sp|Q6S8J3|POTEE_HUMAN,sp|P63261|ACTG_HUMAN,sp|P68133|ACTS_HUMAN,sp|P62736|ACTA_HUMAN,sp|Q9BYX7|ACTBM_HUMAN,sp|P68032|ACTC_HUMAN,sp|Q562R1|ACTBL_HUMAN,sp|P60709|ACTB_HUMAN,sp|P63267|ACTH_HUMAN,sp|A5A3E0|POTEF_HUMAN,tr|A0A804GS07|A0A804GS07_HUMAN,tr|E7EVS6|E7EVS6_HUMAN,tr|A0A6Q8PFE4|A0A6Q8PFE4_HUMAN,tr|A0A2R8YEA7|A0A2R8YEA7_HUMAN,tr|A0A804HKV3|A0A804HKV3_HUMAN,tr|A0A2R8Y793|A0A2R8Y793_HUMAN,tr|I3L4N8|I3L4N8_HUMAN,tr|A6NL76|A6NL76_HUMAN" 18 1789.8846 1.06 37067 22386 2 1789.881731 895.9496 POTE ankyrin domain family member E OS=Homo sapiens OX=9606 GN=POTEE PE=2 SV=3 4.14 3552.7 - 2.17E+06 - - - -1.6269 - 3.136 0.679 - 862.1 1 2 0 -0.0029 16 0 0 0 2.60E+08 2.44E+08 - - - 6.8652 0.9993 221125_WJC_METTL3_EV_vs_WT_F03.22387.22387.3 0.035 13/40 R.INLWHLEITDR[166.11].S "sp|Q66LE6|2ABD_HUMAN,sp|P63151|2ABA_HUMAN,tr|A0A590UJJ1|A0A590UJJ1_HUMAN,tr|A0A590UJY3|A0A590UJY3_HUMAN" 4 1418.7546 0.51 37068 22387 3 1418.754918 473.9255 Serine\threonine-protein phosphatase 2A 55 kDa regulatory subunit B delta isoform OS=Homo sapiens OX=9606 GN=PPP2R2D PE=1 SV=1 5.32 3552.8 - 2.14E+06 - - - 0.246 - 2.372 0.235 - 345.7 1 2 0 0.0003 11 0 0 0 1.16E+07 2.30E+07 - - - 3.6136 1 221125_WJC_METTL3_EV_vs_WT_F03.22388.22388.2 4.31E-16 24/44 K.AFSAVDTDGNGTINAQELGAALK.A sp|Q9NZT1|CALL5_HUMAN 1 2262.1128 999 37069 22388 2 2262.115614 1132.0637 Calmodulin-like protein 5 OS=Homo sapiens OX=9606 GN=CALML5 PE=1 SV=2 4.03 3553 - 2.14E+06 - - - 1.2418 - 4.307 0.765 - 1482.9 1 2 0 0.0028 23 0 0 0 7.89E+07 0.00E+00 - - - 8.2805 1 221125_WJC_METTL3_EV_vs_WT_F03.22389.22389.3 4.67E-10 24/100 K.LQVEPAVDTSGVQC[160.03]YGPGIEGQGVFR[166.11].E "sp|P21333|FLNA_HUMAN,tr|Q60FE5|Q60FE5_HUMAN" 2 2772.3416 0.85 37070 22389 3 2772.342757 925.1212 Filamin-A OS=Homo sapiens OX=9606 GN=FLNA PE=1 SV=4 4.14 3553.1 - 1.87E+06 - - - 0.3993 - 3.635 0.611 - 359 1 2 0 0.0011 26 0 0 0 1.38E+07 1.63E+07 - - - 8.321 1 221125_WJC_METTL3_EV_vs_WT_F03.22390.22390.2 0.000158 16/28 K.ESEITDEDIDGILER.G sp|O60264|SMCA5_HUMAN 1 1732.8003 2.69 37071 22390 2 1732.799697 867.4074 SWI\SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A member 5 OS=Homo sapiens OX=9606 GN=SMARCA5 PE=1 SV=1 3.66 3553.2 - 1.43E+06 - - - -0.3503 - 3.285 0.569 - 1049.2 1 2 0 -0.0006 15 0 0 0 2.64E+07 9.85E+06 - - - 6.1676 1 221125_WJC_METTL3_EV_vs_WT_F03.22396.22396.3 4.60E-09 16/60 R.IHFPLATYAPVISAEK[136.11].A "sp|Q6PEY2|TBA3E_HUMAN,sp|P0DPH7|TBA3C_HUMAN,sp|Q71U36|TBA1A_HUMAN,sp|P0DPH8|TBA3D_HUMAN,sp|P68366|TBA4A_HUMAN,sp|P68363|TBA1B_HUMAN,sp|Q9BQE3|TBA1C_HUMAN,tr|F8VVB9|F8VVB9_HUMAN,tr|C9JDS9|C9JDS9_HUMAN,tr|A0A1W2PQM2|A0A1W2PQM2_HUMAN,tr|F5H5D3|F5H5D3_HUMAN" 11 1763.9702 0.63 37076 22396 3 1763.969065 588.9973 Tubulin alpha-3E chain OS=Homo sapiens OX=9606 GN=TUBA3E PE=1 SV=2 6.75 3553.9 - 2.33E+07 - - - -0.6191 - 2.707 0.642 - 277.8 1 2 0 -0.0011 16 0 0 0 3.32E+08 5.27E+08 - - - 8.2526 1 221125_WJC_METTL3_EV_vs_WT_F03.22398.22398.3 6.21E-07 16/64 R.DQSAVVVQGLPEGVAFK[136.11].H "sp|P78347|GTF2I_HUMAN,tr|A0A494C1K3|A0A494C1K3_HUMAN" 2 1750.9345 1.55 37077 22398 3 1750.932878 584.6521 General transcription factor II-I OS=Homo sapiens OX=9606 GN=GTF2I PE=1 SV=2 4.37 3554.1 - 2.57E+07 - - - -0.9264 - 3.246 0.527 - 274.6 1 2 0 -0.0016 17 0 0 0 4.13E+08 2.65E+08 - - - 7.3896 0.9999 221125_WJC_METTL3_EV_vs_WT_F03.22402.22402.3 9.62E-05 15/52 K.SLQESR[166.11]PFSVDFFR[166.11].K "sp|Q9NYH9|UTP6_HUMAN,tr|J3KRR8|J3KRR8_HUMAN" 2 1733.864 1.32 37081 22402 3 1733.864084 578.9619 U3 small nucleolar RNA-associated protein 6 homolog OS=Homo sapiens OX=9606 GN=UTP6 PE=1 SV=2 5.79 3554.4 - 1.77E+06 - - - 0.0427 - 2.405 0.427 - 224.9 1 2 0 0.0001 14 0 0 0 9.84E+06 7.46E+06 - - - 5.6327 0.9995 221125_WJC_METTL3_EV_vs_WT_F03.22403.22403.2 0.00162 16/32 K.GIEILTDMSR[166.11]PVELSDR[166.11].E sp|P50991|TCPD_HUMAN 1 1949.9995 0.13 37082 22403 2 1949.994107 976.007 T-complex protein 1 subunit delta OS=Homo sapiens OX=9606 GN=CCT4 PE=1 SV=4 4.32 3554.5 - 1.30E+06 - - - -2.7744 - 2.602 0.437 - 239.9 1 2 0 -0.0054 17 0 0 0 2.12E+06 1.61E+07 - - - 4.618 0.9995 221125_WJC_METTL3_EV_vs_WT_F03.22405.22405.3 0.00854 13/40 R.INLWHLEITDR.S "sp|Q66LE6|2ABD_HUMAN,sp|P63151|2ABA_HUMAN,tr|A0A590UJJ1|A0A590UJJ1_HUMAN,tr|A0A590UJY3|A0A590UJY3_HUMAN" 4 1408.7463 0.51 37084 22405 3 1408.744138 470.5894 Serine\threonine-protein phosphatase 2A 55 kDa regulatory subunit B delta isoform OS=Homo sapiens OX=9606 GN=PPP2R2D PE=1 SV=1 5.32 3554.8 - 1.04E+06 - - - -1.534 - 2.417 0.265 - 396.2 1 2 0 -0.0022 11 0 0 0 1.16E+07 2.30E+07 - - - 4.001 1 221125_WJC_METTL3_EV_vs_WT_F03.22408.22408.3 1.79E-10 20/68 R.INPYMSSPC[160.03]HIEMILTEK[136.11].E "sp|P18621|RL17_HUMAN,tr|J3QLC8|J3QLC8_HUMAN,tr|J3QQT2|J3QQT2_HUMAN,tr|A0A0A0MRF8|A0A0A0MRF8_HUMAN,tr|J3KRX5|J3KRX5_HUMAN,tr|A0A087WXM6|A0A087WXM6_HUMAN,tr|A0A0A6YYL6|A0A0A6YYL6_HUMAN" 7 2170.0352 0.77 37085 22408 3 2170.031965 724.3523 60S ribosomal protein L17 OS=Homo sapiens OX=9606 GN=RPL17 PE=1 SV=3 5.4 3555.1 - 7.08E+06 - - - -1.4995 - 3.627 0.629 - 509.1 1 2 0 -0.0033 18 0 0 0 8.81E+07 1.14E+08 - - - 8.7601 1 221125_WJC_METTL3_EV_vs_WT_F03.22409.22409.3 1.06E-06 13/60 R.IINEPTAAAIAYGLDR[166.11].T "sp|P0DMV8|HS71A_HUMAN,sp|P0DMV9|HS71B_HUMAN,sp|P17066|HSP76_HUMAN,tr|A0A0G2JIW1|A0A0G2JIW1_HUMAN" 4 1696.9024 0.22 37086 22409 3 1696.899334 566.6414 Heat shock 70 kDa protein 1A OS=Homo sapiens OX=9606 GN=HSPA1A PE=1 SV=1 4.37 3555.2 - 3.17E+06 - - - -1.7803 - 3.217 0.506 - 155.8 1 2 0 -0.003 16 0 0 0 1.31E+07 6.06E+07 - - - 7.1786 1 221125_WJC_METTL3_EV_vs_WT_F03.22410.22410.3 1.84E-07 25/80 K.LLAALLEDEGGSGR[166.11]PLLQAAK[136.11].G sp|Q9Y490|TLN1_HUMAN 1 2139.2018 1 37087 22410 3 2139.198716 714.0746 Talin-1 OS=Homo sapiens OX=9606 GN=TLN1 PE=1 SV=3 4.68 3555.3 - 2.80E+06 - - - -1.4599 - 3.98 0.515 - 427.8 1 2 0 -0.0031 21 0 0 0 1.96E+07 1.96E+07 - - - 7.5924 1 221125_WJC_METTL3_EV_vs_WT_F03.22412.22412.3 6.24E-15 24/100 K.LQVEPAVDTSGVQC[160.03]YGPGIEGQGVFR.E "sp|P21333|FLNA_HUMAN,tr|Q60FE5|Q60FE5_HUMAN" 2 2762.3334 0.85 37089 22412 3 2762.330706 921.7851 Filamin-A OS=Homo sapiens OX=9606 GN=FLNA PE=1 SV=4 4.14 3555.4 - 1.68E+06 - - - -0.968 - 3.698 0.691 - 674.5 1 2 0 -0.0027 26 0 0 0 1.38E+07 1.63E+07 - - - 9.252 0.9978 221125_WJC_METTL3_EV_vs_WT_F03.22413.22413.2 0.00543 14/28 R.ELGIC[160.03]PDDAAVIPIK.N sp|P12273|PIP_HUMAN 1 1609.8385 999 37090 22413 2 1609.83313 805.9265 Prolactin-inducible protein OS=Homo sapiens OX=9606 GN=PIP PE=1 SV=1 4.03 3555.6 - 1.46E+06 - - - -3.3637 - 2.202 0.318 - 587 1 2 0 -0.0054 15 0 0 0 1.76E+07 0.00E+00 - - - 3.3287 0.9999 221125_WJC_METTL3_EV_vs_WT_F03.22421.22421.2 2.64E-06 16/30 R.IINEPTAAAIAYGLDR[166.11].T "sp|P0DMV8|HS71A_HUMAN,sp|P0DMV9|HS71B_HUMAN,sp|P17066|HSP76_HUMAN,tr|A0A0G2JIW1|A0A0G2JIW1_HUMAN" 4 1696.9024 0.18 37096 22421 2 1696.90106 849.4585 Heat shock 70 kDa protein 1A OS=Homo sapiens OX=9606 GN=HSPA1A PE=1 SV=1 4.37 3556.6 - 7.67E+06 - - - -0.7632 - 3.081 0.522 - 759.9 1 2 0 -0.0013 16 0 0 0 1.49E+07 8.50E+07 - - - 5.6626 0.9999 221125_WJC_METTL3_EV_vs_WT_F03.22423.22423.2 4.25E-07 22-Dec R.DTQSGSLLFIGR.L "sp|P50454|SERPH_HUMAN,tr|E9PKH2|E9PKH2_HUMAN,tr|H0YEP8|H0YEP8_HUMAN" 3 1292.6725 1.03 37098 22423 2 1292.672187 647.3435 Serpin H1 OS=Homo sapiens OX=9606 GN=SERPINH1 PE=1 SV=2 5.84 3556.7 - 3.51E+06 - - - -0.2151 - 2.55 0.561 - 663.4 1 2 0 -0.0003 12 0 0 0 8.84E+07 8.55E+07 - - - 5.6475 1 221125_WJC_METTL3_EV_vs_WT_F03.22425.22425.3 2.37E-06 14/52 R.EYFSWEGAFQHVGK.A sp|P26641|EF1G_HUMAN 1 1683.7682 0.92 37100 22425 3 1683.766242 562.2633 Elongation factor 1-gamma OS=Homo sapiens OX=9606 GN=EEF1G PE=1 SV=3 5.4 3556.9 - 2.77E+06 - - - -1.1373 - 2.364 0.488 - 137.6 1 2 0 -0.0019 14 0 0 0 7.13E+07 7.79E+07 - - - 6.2666 0.9971 221125_WJC_METTL3_EV_vs_WT_F03.22427.22427.2 0.11 14-Jul R.LTILELER[166.11].E sp|Q569K6|CC157_HUMAN 1 995.5891 0.001 37102 22427 2 995.58781 498.8018 Coiled-coil domain-containing protein 157 OS=Homo sapiens OX=9606 GN=CCDC157 PE=1 SV=3 4.53 3557 - 2.42E+06 - - - -1.2626 - 1.482 0.206 - 103.3 1 2 0 -0.0013 8 0 0 0 0.00E+00 2.42E+07 - - - 1.7486 1 221125_WJC_METTL3_EV_vs_WT_F03.22429.22429.3 5.96E-12 23/68 K.EFLLSLDDSVDETEAVK[136.11]R[166.11].Y "sp|Q9BXP5|SRRT_HUMAN,tr|H7C0U8|H7C0U8_HUMAN,tr|A0A286YEP7|A0A286YEP7_HUMAN" 3 2083.044 1.02 37104 22429 3 2083.047975 695.3553 Serrate RNA effector molecule homolog OS=Homo sapiens OX=9606 GN=SRRT PE=1 SV=1 4.02 3557.2 - 1.81E+06 - - - 1.9083 - 4.563 0.647 - 778.4 1 2 0 0.004 18 0 0 0 2.89E+07 2.83E+07 - - - 9.5322 0.9169 221125_WJC_METTL3_EV_vs_WT_F03.22430.22430.2 0.014 16-Sep K.K[136.11]QDEPIDLF.M sp|P40227|TCPZ_HUMAN 1 1111.5641 0.33 37105 22430 2 1111.56151 556.7893 T-complex protein 1 subunit zeta OS=Homo sapiens OX=9606 GN=CCT6A PE=1 SV=3 4.03 3557.4 - 1.52E+06 - - - -2.3211 - 1.689 0.32 - 169.9 1 1 0 -0.0026 9 0 0 0 4.64E+06 1.40E+07 - - - 2.9201 1 221125_WJC_METTL3_EV_vs_WT_F03.22433.22433.3 6.63E-15 20/88 K.AFSAVDTDGNGTINAQELGAALK.A sp|Q9NZT1|CALL5_HUMAN 1 2262.1128 1121.88 37107 22433 3 2262.111033 755.0449 Calmodulin-like protein 5 OS=Homo sapiens OX=9606 GN=CALML5 PE=1 SV=2 4.03 3557.7 - 1.72E+07 - - - -0.7833 - 3.474 0.7 - 501.4 1 2 0 -0.0018 23 0 0 0 2.59E+08 2.31E+05 - - - 9.2652 1 221125_WJC_METTL3_EV_vs_WT_F03.22435.22435.3 2.38E-06 13/52 R.EYFSWEGAFQHVGK[136.11].A sp|P26641|EF1G_HUMAN 1 1691.7824 0.92 37109 22435 3 1691.782551 564.9347 Elongation factor 1-gamma OS=Homo sapiens OX=9606 GN=EEF1G PE=1 SV=3 5.4 3557.8 - 8.33E+06 - - - 0.1147 - 2.139 0.509 - 121.4 1 2 0 0.0002 14 0 0 0 7.13E+07 7.79E+07 - - - 6.2354 0.9998 221125_WJC_METTL3_EV_vs_WT_F03.22437.22437.3 6.35E-06 Nov-44 R.AK[136.11]FEELNMDLFR[166.11].S "sp|P11021|BIP_HUMAN,tr|A0A7P0TB36|A0A7P0TB36_HUMAN" 2 1529.7667 0.54 37111 22437 3 1529.766208 510.9295 Endoplasmic reticulum chaperone BiP OS=Homo sapiens OX=9606 GN=HSPA5 PE=1 SV=2 4.68 3557.9 - 3.44E+06 - - - -0.3347 - 2.367 0.476 - 243.9 1 2 1 -0.0005 12 0 0 0 7.22E+07 1.33E+08 - - - 6.2351 0.9998 221125_WJC_METTL3_EV_vs_WT_F03.22439.22439.2 5.12E-06 17/30 K.VEGTDVTGIEEVVIPK[136.11].K "sp|Q96EY7|PTCD3_HUMAN,tr|F8WE76|F8WE76_HUMAN,tr|B8ZZQ4|B8ZZQ4_HUMAN" 3 1691.9073 1.31 37113 22439 2 1691.910042 846.9609 "Pentatricopeptide repeat domain-containing protein 3, mitochondrial OS=Homo sapiens OX=9606 GN=PTCD3 PE=1 SV=3" 4 3558.1 - 1.42E+06 - - - 1.6313 - 2.849 0.537 - 650.5 1 2 0 0.0028 16 0 0 0 2.31E+07 1.75E+07 - - - 5.5804 0.9997 221125_WJC_METTL3_EV_vs_WT_F03.22440.22440.3 4.43E-06 15/44 R.AKFEELNMDLFR.S "sp|P11021|BIP_HUMAN,tr|A0A7P0TB36|A0A7P0TB36_HUMAN" 2 1511.7442 0.54 37114 22440 3 1511.741867 504.922 Endoplasmic reticulum chaperone BiP OS=Homo sapiens OX=9606 GN=HSPA5 PE=1 SV=2 4.68 3558.2 - 1.39E+06 - - - -1.5763 - 2.282 0.472 - 435.4 1 2 1 -0.0024 12 0 0 0 7.22E+07 1.33E+08 - - - 6.0886 1 221125_WJC_METTL3_EV_vs_WT_F03.22448.22448.3 2.67E-09 15/60 R.IHFPLATYAPVISAEK.A "sp|Q6PEY2|TBA3E_HUMAN,sp|P0DPH7|TBA3C_HUMAN,sp|Q71U36|TBA1A_HUMAN,sp|P0DPH8|TBA3D_HUMAN,sp|P68366|TBA4A_HUMAN,sp|P68363|TBA1B_HUMAN,sp|Q9BQE3|TBA1C_HUMAN,tr|F8VVB9|F8VVB9_HUMAN,tr|C9JDS9|C9JDS9_HUMAN,tr|A0A1W2PQM2|A0A1W2PQM2_HUMAN,tr|F5H5D3|F5H5D3_HUMAN" 11 1755.956 0.62 37120 22448 3 1755.956056 586.3259 Tubulin alpha-3E chain OS=Homo sapiens OX=9606 GN=TUBA3E PE=1 SV=2 6.75 3559.2 - 1.31E+07 - - - 0.0564 - 3.007 0.646 - 263.4 1 2 0 0.0001 16 0 0 0 3.48E+08 5.58E+08 - - - 8.5671 1 221125_WJC_METTL3_EV_vs_WT_F03.22449.22449.2 3.53E-09 14/30 K.SYELPDGQVITIGNER[166.11].F "sp|Q6S8J3|POTEE_HUMAN,sp|P63261|ACTG_HUMAN,sp|P68133|ACTS_HUMAN,sp|P62736|ACTA_HUMAN,sp|Q9BYX7|ACTBM_HUMAN,sp|P68032|ACTC_HUMAN,sp|Q562R1|ACTBL_HUMAN,sp|P60709|ACTB_HUMAN,sp|P63267|ACTH_HUMAN,sp|A5A3E0|POTEF_HUMAN,tr|A0A804GS07|A0A804GS07_HUMAN,tr|E7EVS6|E7EVS6_HUMAN,tr|A0A6Q8PFE4|A0A6Q8PFE4_HUMAN,tr|A0A2R8YEA7|A0A2R8YEA7_HUMAN,tr|A0A804HKV3|A0A804HKV3_HUMAN,tr|A0A2R8Y793|A0A2R8Y793_HUMAN,tr|I3L4N8|I3L4N8_HUMAN,tr|A6NL76|A6NL76_HUMAN" 18 1799.8929 1.06 37121 22449 2 1799.890923 900.9537 POTE ankyrin domain family member E OS=Homo sapiens OX=9606 GN=POTEE PE=2 SV=3 4.14 3559.3 - 7.42E+06 - - - -1.1056 - 2.823 0.657 - 575.7 1 2 0 -0.002 16 0 0 0 2.60E+08 2.44E+08 - - - 6.4445 0.9999 221125_WJC_METTL3_EV_vs_WT_F03.22451.22451.2 2.34E-06 18-Nov R.NMQDLVEDFK.N "sp|P13647|K2C5_HUMAN,tr|F8W0C6|F8W0C6_HUMAN" 2 1237.5649 999 37123 22451 2 1237.564155 619.7897 "Keratin, type II cytoskeletal 5 OS=Homo sapiens OX=9606 GN=KRT5 PE=1 SV=3" 4.03 3559.3 - 7.81E+06 - - - -0.5931 - 2.253 0.549 - 500.8 1 2 0 -0.0007 10 0 0 0 4.14E+08 0.00E+00 - - - 5.363 1 221125_WJC_METTL3_EV_vs_WT_F03.22455.22455.2 3.44E-07 14/30 R.IINEPTAAAIAYGLDR.T "sp|P0DMV8|HS71A_HUMAN,sp|P0DMV9|HS71B_HUMAN,sp|P17066|HSP76_HUMAN,tr|A0A0G2JIW1|A0A0G2JIW1_HUMAN" 4 1686.8941 0.18 37127 22455 2 1686.893147 844.4543 Heat shock 70 kDa protein 1A OS=Homo sapiens OX=9606 GN=HSPA1A PE=1 SV=1 4.37 3559.7 - 1.59E+06 - - - -0.5561 - 3.196 0.575 - 487 1 2 0 -0.0009 16 0 0 0 1.49E+07 8.50E+07 - - - 6.1442 0.9999 221125_WJC_METTL3_EV_vs_WT_F03.22456.22456.3 3.87E-09 22/56 R.LKLPSIPLVPVSAQK.R sp|Q15785|TOM34_HUMAN 1 1588.9916 1.55 37128 22456 3 1588.994831 530.6711 Mitochondrial import receptor subunit TOM34 OS=Homo sapiens OX=9606 GN=TOMM34 PE=1 SV=2 10 3559.8 - 1.55E+06 - - - 2.0239 - 3.479 0.544 - 620.3 1 2 1 0.0032 15 0 0 0 1.23E+07 7.97E+06 - - - 7.8574 0.9872 221125_WJC_METTL3_EV_vs_WT_F03.22457.22457.2 4.38E-05 26-Dec L.LTPLNLQIDPSIQR.V "sp|P13647|K2C5_HUMAN,tr|F8W0C6|F8W0C6_HUMAN,tr|F8VU69|F8VU69_HUMAN" 3 1606.9043 999 37129 22457 2 1606.903551 804.4594 "Keratin, type II cytoskeletal 5 OS=Homo sapiens OX=9606 GN=KRT5 PE=1 SV=3" 5.84 3559.9 - 1.37E+06 - - - -0.4387 - 2.177 0.408 - 320.3 1 1 0 -0.0007 14 0 0 0 8.41E+06 0.00E+00 - - - 4.0065 0.8126 221125_WJC_METTL3_EV_vs_WT_F03.22458.22458.2 0.000633 24-Nov L.LSSSFDLDYDFQR.D "sp|P07910|HNRPC_HUMAN,tr|G3V575|G3V575_HUMAN,tr|G3V576|G3V576_HUMAN,tr|G3V555|G3V555_HUMAN,tr|G3V2Q1|G3V2Q1_HUMAN" 5 1591.7155 77.45 37130 22458 2 1591.707048 796.865 Heterogeneous nuclear ribonucleoproteins C1\C2 OS=Homo sapiens OX=9606 GN=HNRNPC PE=1 SV=4 3.93 3560.1 - 1.31E+06 - - - -5.2798 - 2.021 0.477 - 260.5 1 1 0 -0.0084 13 0 0 0 1.55E+07 2.00E+05 - - - 4.3673 0.9821 221125_WJC_METTL3_EV_vs_WT_F03.22460.22460.3 0.0339 15/64 L.GNQLDGIHLLDPDVVAR[166.11].F sp|Q86U44|MTA70_HUMAN 1 1840.9671 0.49 37132 22460 3 1840.965611 614.663 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 4.41 3560.2 - 1.08E+06 - - - -0.7985 - 2.475 0.346 - 154.2 1 1 0 -0.0015 17 0 0 0 1.20E+07 2.47E+07 - - - 4.6866 0.9833 221125_WJC_METTL3_EV_vs_WT_F03.22467.22467.3 0.238 Sep-36 K.SAEFLLHMLK.N "sp|P18621|RL17_HUMAN,tr|A0A087WWH0|A0A087WWH0_HUMAN,tr|J3QS96|J3QS96_HUMAN,tr|J3QLC8|J3QLC8_HUMAN,tr|J3QQT2|J3QQT2_HUMAN,tr|A0A087WY81|A0A087WY81_HUMAN,tr|A0A0A0MRF8|A0A0A0MRF8_HUMAN,tr|J3KRB3|J3KRB3_HUMAN,tr|J3KRX5|J3KRX5_HUMAN,tr|A0A087WXM6|A0A087WXM6_HUMAN,tr|A0A0A6YYL6|A0A0A6YYL6_HUMAN" 11 1187.6373 0.91 37139 22467 3 1187.636763 396.8864 60S ribosomal protein L17 OS=Homo sapiens OX=9606 GN=RPL17 PE=1 SV=3 6.47 3561.1 - 450425 - - - -0.4235 - 1.495 0.16 - 83.3 1 2 0 -0.0005 10 0 0 0 1.78E+06 1.94E+06 - - - 1.4981 1 221125_WJC_METTL3_EV_vs_WT_F03.22471.22471.3 8.01E-17 24/84 R.TVYGGGC[160.03]SEMLMAHAVTQLANR[166.11].T "sp|P78371|TCPB_HUMAN,tr|F5GWF6|F5GWF6_HUMAN" 2 2375.106 0.33 37142 22471 3 2375.104282 792.7093 T-complex protein 1 subunit beta OS=Homo sapiens OX=9606 GN=CCT2 PE=1 SV=4 6.41 3561.6 - 9.17E+06 - - - -0.7132 - 4.682 0.757 - 437.5 1 2 0 -0.0017 22 0 0 0 4.60E+07 1.38E+08 - - - 10.6392 1 221125_WJC_METTL3_EV_vs_WT_F03.22472.22472.3 2.92E-07 Dec-60 R.TAFTSQQLLELEHQFK.L "sp|P50219|MNX1_HUMAN,tr|C9K088|C9K088_HUMAN" 2 1918.9789 2.56 37143 22472 3 1918.979368 640.6669 Motor neuron and pancreas homeobox protein 1 OS=Homo sapiens OX=9606 GN=MNX1 PE=1 SV=3 5.37 3561.6 - 5.40E+06 - - - 0.2553 - 2.4 0.485 - 121.8 1 2 0 0.0005 16 0 0 0 5.21E+07 2.04E+07 - - - 6.1935 1 221125_WJC_METTL3_EV_vs_WT_F03.22473.22473.3 1.83E-08 14/60 K.SYELPDGQVITIGNER[166.11].F "sp|Q6S8J3|POTEE_HUMAN,sp|P63261|ACTG_HUMAN,sp|P68133|ACTS_HUMAN,sp|P62736|ACTA_HUMAN,sp|Q9BYX7|ACTBM_HUMAN,sp|P68032|ACTC_HUMAN,sp|Q562R1|ACTBL_HUMAN,sp|P60709|ACTB_HUMAN,sp|P63267|ACTH_HUMAN,sp|A5A3E0|POTEF_HUMAN,tr|A0A804GS07|A0A804GS07_HUMAN,tr|E7EVS6|E7EVS6_HUMAN,tr|A0A6Q8PFE4|A0A6Q8PFE4_HUMAN,tr|A0A2R8YEA7|A0A2R8YEA7_HUMAN,tr|A0A804HKV3|A0A804HKV3_HUMAN,tr|A0A2R8Y793|A0A2R8Y793_HUMAN,tr|I3L4N8|I3L4N8_HUMAN,tr|A6NL76|A6NL76_HUMAN" 18 1799.8929 1.29 37144 22473 3 1799.892212 600.9716 POTE ankyrin domain family member E OS=Homo sapiens OX=9606 GN=POTEE PE=2 SV=3 4.14 3561.6 - 5.33E+06 - - - -0.3895 - 2.613 0.585 - 235.8 1 2 0 -0.0007 16 0 0 0 1.05E+08 8.08E+07 - - - 7.5265 1 221125_WJC_METTL3_EV_vs_WT_F03.22475.22475.3 2.32E-05 13/44 K.VHLVGIDIFTGK[136.11].K "sp|P63241|IF5A1_HUMAN,sp|Q9GZV4|IF5A2_HUMAN,sp|Q6IS14|IF5AL_HUMAN,tr|C9J4W5|C9J4W5_HUMAN,tr|I3L397|I3L397_HUMAN,tr|I3L504|I3L504_HUMAN,tr|C9J7B5|C9J7B5_HUMAN,tr|F8WCJ1|F8WCJ1_HUMAN" 8 1305.7536 0.87 37146 22475 3 1305.752961 436.2585 Eukaryotic translation initiation factor 5A-1 OS=Homo sapiens OX=9606 GN=EIF5A PE=1 SV=2 6.71 3561.8 - 2.18E+06 - - - -0.507 - 2.743 0.472 - 424.4 1 2 0 -0.0007 12 0 0 0 4.74E+07 5.47E+07 - - - 6.5991 1 221125_WJC_METTL3_EV_vs_WT_F03.22478.22478.3 1.60E-08 15/44 K.VHLVGIDIFTGK.K "sp|P63241|IF5A1_HUMAN,sp|Q9GZV4|IF5A2_HUMAN,sp|Q6IS14|IF5AL_HUMAN,tr|C9J4W5|C9J4W5_HUMAN,tr|I3L397|I3L397_HUMAN,tr|I3L504|I3L504_HUMAN,tr|C9J7B5|C9J7B5_HUMAN,tr|F8WCJ1|F8WCJ1_HUMAN" 8 1297.7394 0.87 37149 22478 3 1297.738464 433.5871 Eukaryotic translation initiation factor 5A-1 OS=Homo sapiens OX=9606 GN=EIF5A PE=1 SV=2 6.71 3562 - 1.59E+06 - - - -0.739 - 2.82 0.596 - 563.8 1 2 0 -0.001 12 0 0 0 4.74E+07 5.47E+07 - - - 8.0582 1 221125_WJC_METTL3_EV_vs_WT_F03.22479.22479.2 5.74E-10 17/42 R.TTGIVMDSGDGVTHTVPIYEGY.A "sp|P63261|ACTG_HUMAN,sp|P60709|ACTB_HUMAN,tr|A0A804GS07|A0A804GS07_HUMAN,tr|I3L3I0|I3L3I0_HUMAN,tr|E7EVS6|E7EVS6_HUMAN,tr|A0A6Q8PFE4|A0A6Q8PFE4_HUMAN,tr|I3L1U9|I3L1U9_HUMAN,tr|A0A2R8YEA7|A0A2R8YEA7_HUMAN,tr|A0A2R8Y793|A0A2R8Y793_HUMAN,tr|I3L4N8|I3L4N8_HUMAN" 10 2311.0678 - 37150 22479 2 2311.071141 1156.5412 "Actin, cytoplasmic 2 OS=Homo sapiens OX=9606 GN=ACTG1 PE=1 SV=1" 4.02 3562.1 - 1.24E+06 - - - 1.4331 - 3.386 0.607 - 592.5 1 1 0 0.0033 22 0 0 0 - - - - - 6.5218 0.9999 221125_WJC_METTL3_EV_vs_WT_F03.22480.22480.3 4.26E-09 19/88 R.ITSGPFEPDLYK[136.11]SEMEVQDAELK[136.11].A sp|Q9UQ80|PA2G4_HUMAN 1 2641.2804 0.001 37151 22480 3 2641.278392 881.4341 Proliferation-associated protein 2G4 OS=Homo sapiens OX=9606 GN=PA2G4 PE=1 SV=3 4.08 3562.3 - 1.18E+06 - - - -0.7606 - 3.636 0.552 - 266.6 1 2 1 -0.002 23 0 0 0 0.00E+00 1.65E+07 - - - 7.722 1 221125_WJC_METTL3_EV_vs_WT_F03.22482.22482.3 2.02E-06 18/48 R.IPLLSDLTHQISK[136.11].D "sp|Q13162|PRDX4_HUMAN,tr|A6NJJ0|A6NJJ0_HUMAN,tr|H7C3T4|H7C3T4_HUMAN" 3 1471.849 0.63 37153 22482 3 1471.849492 491.6236 Peroxiredoxin-4 OS=Homo sapiens OX=9606 GN=PRDX4 PE=1 SV=1 6.74 3562.5 - 888364 - - - 0.3479 - 3.07 0.513 - 490.5 1 2 0 0.0005 13 0 0 0 7.13E+07 1.14E+08 - - - 7.3005 1 221125_WJC_METTL3_EV_vs_WT_F03.22483.22483.3 2.58E-08 18/48 R.IPLLSDLTHQISK.D "sp|Q13162|PRDX4_HUMAN,tr|A6NJJ0|A6NJJ0_HUMAN,tr|H7C3T4|H7C3T4_HUMAN" 3 1463.8348 0.63 37154 22483 3 1463.8332 488.9522 Peroxiredoxin-4 OS=Homo sapiens OX=9606 GN=PRDX4 PE=1 SV=1 6.74 3562.7 - 362718 - - - -1.0794 - 3.132 0.534 - 495.3 1 2 0 -0.0016 13 0 0 0 7.12E+07 1.14E+08 - - - 7.5885 0.9999 221125_WJC_METTL3_EV_vs_WT_F03.22486.22486.2 2.53E-05 22-Dec K.DSIVQGFQWGTR.E "sp|Q15029|U5S1_HUMAN,tr|K7EJ74|K7EJ74_HUMAN,tr|K7EP67|K7EP67_HUMAN" 3 1392.6786 2.17 37155 22486 2 1392.678658 697.3466 116 kDa U5 small nuclear ribonucleoprotein component OS=Homo sapiens OX=9606 GN=EFTUD2 PE=1 SV=1 5.84 3563.1 - 8.02E+06 - - - 0.0323 - 2.289 0.545 - 537.7 1 2 0 0 12 0 0 0 6.87E+07 3.16E+07 - - - 5.2453 0.9999 221125_WJC_METTL3_EV_vs_WT_F03.22487.22487.2 2.50E-07 24-Dec K.GSFSEQGINEFLR[166.11].E sp|Q15084|PDIA6_HUMAN 1 1492.7186 1.21 37156 22487 2 1492.718962 747.3666 Protein disulfide-isomerase A6 OS=Homo sapiens OX=9606 GN=PDIA6 PE=1 SV=1 4.53 3563.1 - 5.15E+06 - - - 0.2579 - 2.659 0.525 - 448.1 1 2 0 0.0004 13 0 0 0 5.61E+07 4.65E+07 - - - 5.4285 1 221125_WJC_METTL3_EV_vs_WT_F03.22488.22488.3 2.63E-09 23/68 R.LTEEETVC[160.03]LDLDKVEAYR.C sp|P15924|DESP_HUMAN 1 2182.0464 26.29 37157 22488 3 2182.044412 728.3561 Desmoplakin OS=Homo sapiens OX=9606 GN=DSP PE=1 SV=3 4.08 3563.1 - 5.03E+06 - - - -0.895 - 4.343 0.628 - 862 1 2 1 -0.002 18 0 0 0 7.17E+07 2.73E+06 - - - 9.1979 1 221125_WJC_METTL3_EV_vs_WT_F03.22489.22489.3 5.04E-05 14/60 R.TAFTSQQLLELEHQFK[136.11].L "sp|P50219|MNX1_HUMAN,tr|C9K088|C9K088_HUMAN" 2 1926.9931 2.6 37158 22489 3 1926.990924 643.3383 Motor neuron and pancreas homeobox protein 1 OS=Homo sapiens OX=9606 GN=MNX1 PE=1 SV=3 5.37 3563.2 - 4.83E+06 - - - -1.1178 - 2.827 0.593 - 199.8 1 2 0 -0.0022 16 0 0 0 5.18E+07 2.00E+07 - - - 7.8173 1 221125_WJC_METTL3_EV_vs_WT_F03.22491.22491.3 8.61E-07 18/84 R.VLNGPEGDGVPEAVVTLNNQIK.V "sp|Q15155|NOMO1_HUMAN,sp|Q5JPE7|NOMO2_HUMAN,sp|P69849|NOMO3_HUMAN,tr|A0A7I2V3P4|A0A7I2V3P4_HUMAN,tr|A0A7I2V6B0|A0A7I2V6B0_HUMAN,tr|A0A7I2V4D7|A0A7I2V4D7_HUMAN,tr|A0A7I2V4T6|A0A7I2V4T6_HUMAN,tr|A0A0G2JP90|A0A0G2JP90_HUMAN,tr|A0A087X117|A0A087X117_HUMAN,tr|A0A0G2JN29|A0A0G2JN29_HUMAN,tr|A0A7I2V2Z5|A0A7I2V2Z5_HUMAN,tr|A0A087WW46|A0A087WW46_HUMAN,tr|J3KN36|J3KN36_HUMAN" 13 2262.1856 1.02 37160 22491 3 2262.186296 755.0691 Nodal modulator 1 OS=Homo sapiens OX=9606 GN=NOMO1 PE=1 SV=5 4.14 3563.3 - 2.88E+06 - - - 0.3183 - 3.189 0.623 - 328.7 1 2 0 0.0007 22 0 0 0 1.59E+07 1.56E+07 - - - 8.2351 1 221125_WJC_METTL3_EV_vs_WT_F03.22492.22492.2 1.53E-13 23/36 R.GSYGDLGGPIITTQVTIPK[136.11].D "sp|P61978|HNRPK_HUMAN,tr|S4R359|S4R359_HUMAN,tr|Q5T6W2|Q5T6W2_HUMAN" 3 1924.0397 1.3 37161 22492 2 1924.038061 963.0271 Heterogeneous nuclear ribonucleoprotein K OS=Homo sapiens OX=9606 GN=HNRNPK PE=1 SV=1 5.83 3563.5 - 2.39E+06 - - - -0.8487 - 3.878 0.735 - 1009.4 1 2 0 -0.0016 19 0 0 0 3.26E+08 2.51E+08 - - - 7.8013 1 221125_WJC_METTL3_EV_vs_WT_F03.22493.22493.2 2.17E-15 25/36 R.GSYGDLGGPIITTQVTIPK.D "sp|P61978|HNRPK_HUMAN,tr|S4R359|S4R359_HUMAN,tr|Q5T6W2|Q5T6W2_HUMAN" 3 1916.0255 1.3 37162 22493 2 1916.027132 959.02 Heterogeneous nuclear ribonucleoprotein K OS=Homo sapiens OX=9606 GN=HNRNPK PE=1 SV=1 5.83 3563.6 - 2.10E+06 - - - 0.8549 - 4.224 0.731 - 1313.5 1 2 0 0.0016 19 0 0 0 3.26E+08 2.51E+08 - - - 7.9819 0.9999 221125_WJC_METTL3_EV_vs_WT_F03.22494.22494.2 1.01E-05 16/30 K.VEGTDVTGIEEVVIPK.K "sp|Q96EY7|PTCD3_HUMAN,tr|F8WE76|F8WE76_HUMAN,tr|B8ZZQ4|B8ZZQ4_HUMAN" 3 1683.8931 1.31 37163 22494 2 1683.892841 842.9538 "Pentatricopeptide repeat domain-containing protein 3, mitochondrial OS=Homo sapiens OX=9606 GN=PTCD3 PE=1 SV=3" 4 3563.7 - 1.27E+06 - - - -0.1431 - 2.828 0.554 - 458.9 1 2 0 -0.0002 16 0 0 0 2.31E+07 1.75E+07 - - - 5.6886 1 221125_WJC_METTL3_EV_vs_WT_F03.22495.22495.3 3.09E-05 21/72 R.QFNLTPPIC[160.03]EQAEYHMFQR.E "sp|Q13303|KCAB2_HUMAN,tr|A0A590UJJ4|A0A590UJJ4_HUMAN,tr|A0A5F9UN28|A0A5F9UN28_HUMAN,tr|A0A590UJB6|A0A590UJB6_HUMAN" 4 2408.1042 2.13 37164 22495 3 2408.107627 803.7087 Voltage-gated potassium channel subunit beta-2 OS=Homo sapiens OX=9606 GN=KCNAB2 PE=1 SV=2 5.4 3563.8 - 1.20E+06 - - - 1.4347 - 3.603 0.502 - 338.9 1 2 0 0.0035 19 0 0 0 2.64E+07 1.24E+07 - - - 7.2849 1 221125_WJC_METTL3_EV_vs_WT_F03.22499.22499.2 5.09E-11 15/26 K.TYEAALETIQNMSK.V sp|O00231|PSD11_HUMAN 1 1597.7658 0.75 37168 22499 2 1597.763093 799.8902 26S proteasome non-ATPase regulatory subunit 11 OS=Homo sapiens OX=9606 GN=PSMD11 PE=1 SV=3 4.53 3564.3 - 894058 - - - -1.6773 - 2.99 0.647 - 581.1 1 2 0 -0.0027 14 0 0 0 7.56E+06 1.00E+07 - - - 6.5674 0.9998 221125_WJC_METTL3_EV_vs_WT_F03.22501.22501.3 0.408 15/44 R.K[136.11]VDVEEEFFALR[166.11].K sp|P46013|KI67_HUMAN 1 1498.7787 0.82 37170 22501 3 1498.777723 500.6002 Proliferation marker protein Ki-67 OS=Homo sapiens OX=9606 GN=MKI67 PE=1 SV=2 4.41 3564.6 - 799198 - - - -0.6285 - 2.673 0.311 - 259.5 1 2 0 -0.0009 12 0 0 0 5.10E+06 6.23E+06 - - - 4.7324 0.9999 221125_WJC_METTL3_EV_vs_WT_F03.22502.22502.3 1.66E-07 15/44 R.KVDVEEEFFALR.K sp|P46013|KI67_HUMAN 1 1480.7562 0.8 37171 22502 3 1480.755213 494.5927 Proliferation marker protein Ki-67 OS=Homo sapiens OX=9606 GN=MKI67 PE=1 SV=2 4.41 3564.7 - 742433 - - - -0.6632 - 2.389 0.421 - 220.8 1 2 0 -0.001 12 0 0 0 5.01E+06 6.23E+06 - - - 5.6474 1 221125_WJC_METTL3_EV_vs_WT_F03.22506.22506.3 1.12E-07 14/72 R.GSYGDLGGPIITTQVTIPK[136.11].D "sp|P61978|HNRPK_HUMAN,tr|S4R359|S4R359_HUMAN,tr|Q5T6W2|Q5T6W2_HUMAN" 3 1924.0397 1.28 37173 22506 3 1924.041787 642.3538 Heterogeneous nuclear ribonucleoprotein K OS=Homo sapiens OX=9606 GN=HNRNPK PE=1 SV=1 5.83 3565.1 - 1.16E+07 - - - 1.0878 - 2.87 0.507 - 179.3 1 2 0 0.0021 19 0 0 0 2.22E+08 1.74E+08 - - - 6.7822 1 221125_WJC_METTL3_EV_vs_WT_F03.22507.22507.3 2.94E-19 24/84 R.TVYGGGC[160.03]SEMLMAHAVTQLANR.T "sp|P78371|TCPB_HUMAN,tr|F5GWF6|F5GWF6_HUMAN" 2 2365.0977 0.33 37174 22507 3 2365.097456 789.3732 T-complex protein 1 subunit beta OS=Homo sapiens OX=9606 GN=CCT2 PE=1 SV=4 6.41 3565.2 - 6.10E+06 - - - -0.1057 - 4.734 0.754 - 469.9 1 2 0 -0.0003 22 0 0 0 4.60E+07 1.38E+08 - - - 10.6324 1 221125_WJC_METTL3_EV_vs_WT_F03.22508.22508.3 5.65E-11 19/68 K.SSILLDVK[136.11]PWDDETDMAK[136.11].L sp|P24534|EF1B_HUMAN 1 2078.0213 0.86 37175 22508 3 2078.020747 693.681 Elongation factor 1-beta OS=Homo sapiens OX=9606 GN=EEF1B2 PE=1 SV=3 4.04 3565.3 - 4.08E+06 - - - -0.2531 - 3.184 0.663 - 433 1 2 0 -0.0005 18 0 0 0 2.44E+07 2.82E+07 - - - 8.8155 0.9977 221125_WJC_METTL3_EV_vs_WT_F03.22512.22512.3 7.28E-05 17/52 K.LLHHLSDLALTLPT.D "sp|Q86U44|MTA70_HUMAN,tr|B4E349|B4E349_HUMAN,tr|F5H6D8|F5H6D8_HUMAN,tr|H0YFV6|H0YFV6_HUMAN,tr|B4DTN4|B4DTN4_HUMAN" 5 1542.877 - 37179 22512 3 1542.876897 515.2996 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 5.97 3565.5 - 2.61E+06 - - - -0.0531 - 3.373 0.465 - 295.4 1 1 0 -0.0001 14 0 0 0 - - - - - 6.9553 0.9999 221125_WJC_METTL3_EV_vs_WT_F03.22513.22513.2 0.0319 15/22 K.VHLVGIDIFTGK[136.11].K "sp|P63241|IF5A1_HUMAN,sp|Q9GZV4|IF5A2_HUMAN,sp|Q6IS14|IF5AL_HUMAN,tr|C9J4W5|C9J4W5_HUMAN,tr|I3L397|I3L397_HUMAN,tr|I3L504|I3L504_HUMAN,tr|C9J7B5|C9J7B5_HUMAN,tr|F8WCJ1|F8WCJ1_HUMAN" 8 1305.7536 0.95 37180 22513 2 1305.754545 653.8841 Eukaryotic translation initiation factor 5A-1 OS=Homo sapiens OX=9606 GN=EIF5A PE=1 SV=2 6.71 3565.6 - 2.13E+06 - - - 0.7061 - 2.739 0.492 - 684.3 1 2 0 0.0009 12 0 0 0 1.55E+07 1.63E+07 - - - 5.3258 1 221125_WJC_METTL3_EV_vs_WT_F03.22516.22516.3 7.03E-11 21/92 K.SYGGYEVVGGSSDSYLVPGMTYSK.G "sp|Q15517|CDSN_HUMAN,tr|G8JLG2|G8JLG2_HUMAN,tr|Q2L6G8|Q2L6G8_HUMAN" 3 2502.1261 999 37183 22516 3 2502.127895 835.0493 Corneodesmosin OS=Homo sapiens OX=9606 GN=CDSN PE=1 SV=3 4.37 3565.8 - 1.70E+06 - - - 0.7286 - 3.599 0.646 - 259.1 1 2 0 0.0018 24 0 0 0 1.40E+07 0.00E+00 - - - 8.7162 1 221125_WJC_METTL3_EV_vs_WT_F03.22518.22518.3 2.41E-07 22/72 R.QFNLTPPIC[160.03]EQAEYHMFQR[166.11].E "sp|Q13303|KCAB2_HUMAN,tr|A0A590UJJ4|A0A590UJJ4_HUMAN,tr|A0A5F9UN28|A0A5F9UN28_HUMAN,tr|A0A590UJB6|A0A590UJB6_HUMAN" 4 2418.1124 2.13 37185 22518 3 2418.115963 807.0448 Voltage-gated potassium channel subunit beta-2 OS=Homo sapiens OX=9606 GN=KCNAB2 PE=1 SV=2 5.4 3566.1 - 1.17E+06 - - - 1.4561 - 3.406 0.58 - 500.5 1 2 0 0.0035 19 0 0 0 2.64E+07 1.24E+07 - - - 8.0164 0.8153 221125_WJC_METTL3_EV_vs_WT_F03.22520.22520.3 0.039 14/76 R.EALATLK[136.11]PQAGLIVPQAVPS.S "sp|Q9UMS4|PRP19_HUMAN,tr|F5GY56|F5GY56_HUMAN,tr|F5H2I0|F5H2I0_HUMAN" 3 2010.1605 1.39 37187 22520 3 2010.1553 671.0608 Pre-mRNA-processing factor 19 OS=Homo sapiens OX=9606 GN=PRPF19 PE=1 SV=1 6.1 3566.4 - 790378 - - - -2.5754 - 2.112 0.281 - 108.4 1 1 0 -0.0052 20 0 0 0 7.63E+06 5.49E+06 - - - 3.4852 0.9995 221125_WJC_METTL3_EV_vs_WT_F03.22522.22522.2 0.000334 Oct-32 K.GDLETLQPGDDVEFTIK[136.11].D "sp|O75534|CSDE1_HUMAN,tr|E9PLT0|E9PLT0_HUMAN,tr|E9PNG3|E9PNG3_HUMAN" 3 1883.9244 0.48 37189 22522 2 1883.923993 942.9695 Cold shock domain-containing protein E1 OS=Homo sapiens OX=9606 GN=CSDE1 PE=1 SV=2 3.77 3566.6 - 562305 - - - -0.2102 - 1.648 0.375 - 165.7 1 2 0 -0.0004 17 0 0 0 2.38E+06 4.93E+06 - - - 3.0388 0.9999 221125_WJC_METTL3_EV_vs_WT_F03.22523.22523.3 0.000323 14/52 R.QLPQVLHMSELLNR.G sp|Q15477|SKIV2_HUMAN 1 1676.9032 2.08 37190 22523 3 1676.903728 559.975 Helicase SKI2W OS=Homo sapiens OX=9606 GN=SKIV2L PE=1 SV=3 6.75 3566.8 - 525316 - - - 0.3089 - 2.332 0.362 - 217.7 1 2 0 0.0005 14 0 0 0 1.67E+07 8.05E+06 - - - 4.826 1 221125_WJC_METTL3_EV_vs_WT_F03.22524.22524.2 2.99E-05 15/36 R.TPASINATPANINLADLTR.A sp|Q7KZ85|SPT6H_HUMAN 1 1952.0327 2.91 37191 22524 2 1952.032627 977.0236 Transcription elongation factor SPT6 OS=Homo sapiens OX=9606 GN=SUPT6H PE=1 SV=2 5.5 3566.9 - 402540 - - - -0.0394 - 3.195 0.546 - 460.7 1 2 0 -0.0001 19 0 0 0 3.02E+06 1.04E+06 - - - 5.9295 1 221125_WJC_METTL3_EV_vs_WT_F03.22528.22528.3 2.47E-09 19/68 K.SSILLDVKPWDDETDMAK.L sp|P24534|EF1B_HUMAN 1 2061.9929 0.86 37193 22528 3 2061.989708 688.3382 Elongation factor 1-beta OS=Homo sapiens OX=9606 GN=EEF1B2 PE=1 SV=3 4.04 3567.4 - 2.79E+06 - - - -1.5349 - 3.326 0.619 - 352.7 1 2 0 -0.0032 18 0 0 0 2.44E+07 2.82E+07 - - - 8.4329 0.9999 221125_WJC_METTL3_EV_vs_WT_F03.22530.22530.4 1.01E-08 23/144 K.VVPAYVPTPIHPIFGGATHSAFGLK[136.11].A sp|Q96HA1|P121A_HUMAN 1 2583.4093 1.96 37195 22530 4 2583.409324 646.8596 Nuclear envelope pore membrane protein POM 121 OS=Homo sapiens OX=9606 GN=POM121 PE=1 SV=2 8.58 3567.6 - 3.00E+06 - - - 0.0035 - 3.315 0.406 - 240.2 1 2 0 0 25 0 0 0 3.88E+07 1.98E+07 - - - 3.1411 1 221125_WJC_METTL3_EV_vs_WT_F03.22531.22531.2 1.30E-12 22/42 R.FGQAATMEGIGAIGGTPPAFNR[166.11].A "sp|Q15233|NONO_HUMAN,tr|A0A7I2V535|A0A7I2V535_HUMAN,tr|A0A7I2V4K9|A0A7I2V4K9_HUMAN,tr|A0A7I2V4J2|A0A7I2V4J2_HUMAN,tr|A0A7I2V5Y7|A0A7I2V5Y7_HUMAN" 5 2172.0661 0.38 37196 22531 2 2172.068502 1087.0403 Non-POU domain-containing octamer-binding protein OS=Homo sapiens OX=9606 GN=NONO PE=1 SV=4 6 3567.7 - 1.38E+06 - - - 1.0861 - 4.321 0.691 - 1258.2 1 2 0 0.0024 22 0 0 0 6.90E+06 1.84E+07 - - - 7.742 1 221125_WJC_METTL3_EV_vs_WT_F03.22536.22536.3 0.000614 17/76 K.ALEESESSQLISPPLAQAIR.D sp|P42166|LAP2A_HUMAN 1 2138.1219 0.83 37201 22536 3 2138.121489 713.7146 "Lamina-associated polypeptide 2, isoform alpha OS=Homo sapiens OX=9606 GN=TMPO PE=1 SV=2" 4.25 3568.3 - 1.02E+06 - - - -0.1983 - 2.772 0.457 - 352.6 1 2 0 -0.0004 20 0 0 0 1.26E+07 1.53E+07 - - - 6.1085 0.9971 221125_WJC_METTL3_EV_vs_WT_F03.22540.22540.2 3.66E-05 14/32 K.SPISVPGGSALISNLGK.V "sp|P51610|HCFC1_HUMAN,tr|A6NEM2|A6NEM2_HUMAN" 2 1595.8883 0.43 37205 22540 2 1595.895791 798.9514 Host cell factor 1 OS=Homo sapiens OX=9606 GN=HCFC1 PE=1 SV=2 8.47 3568.8 - 641127 - - - 4.7115 - 2.189 0.443 - 394.4 1 2 0 0.0075 17 0 0 0 5.73E+06 1.32E+07 - - - 4.2368 0.9939 221125_WJC_METTL3_EV_vs_WT_F03.22548.22548.2 3.16E-06 26-Dec K.LLHHLSDLALTLPT.D "sp|Q86U44|MTA70_HUMAN,tr|B4E349|B4E349_HUMAN,tr|F5H6D8|F5H6D8_HUMAN,tr|H0YFV6|H0YFV6_HUMAN,tr|B4DTN4|B4DTN4_HUMAN" 5 1542.877 - 37211 22548 2 1542.876257 772.4458 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 5.97 3569.8 - 2.69E+06 - - - -0.468 - 2.412 0.536 - 245.5 1 1 0 -0.0007 14 0 0 0 - - - - - 5.2091 1 221125_WJC_METTL3_EV_vs_WT_F03.22549.22549.4 2.34E-07 31/144 K.VVPAYVPTPIHPIFGGATHSAFGLK.A sp|Q96HA1|P121A_HUMAN 1 2575.3951 1.84 37212 22549 4 2575.396966 644.8561 Nuclear envelope pore membrane protein POM 121 OS=Homo sapiens OX=9606 GN=POM121 PE=1 SV=2 8.58 3569.8 - 7.20E+06 - - - 0.7187 - 4.184 0.603 - 457.6 1 2 0 0.0019 25 0 0 0 3.52E+07 1.91E+07 - - - 4.9293 1 221125_WJC_METTL3_EV_vs_WT_F03.22550.22550.3 8.47E-09 21/68 R.SLGETQLVLYGDVEELKR.S sp|Q07065|CKAP4_HUMAN 1 2048.079 1.86 37213 22550 3 2048.080292 683.7003 Cytoskeleton-associated protein 4 OS=Homo sapiens OX=9606 GN=CKAP4 PE=1 SV=2 4.41 3569.9 - 2.13E+06 - - - 0.6377 - 3.827 0.594 - 381.3 1 2 0 0.0013 18 0 0 0 3.78E+07 2.03E+07 - - - 8.5041 1 221125_WJC_METTL3_EV_vs_WT_F03.22553.22553.3 1.82E-10 14/52 K.R[166.11]TDDIPVWDQEFLK[136.11].V "sp|P63208|SKP1_HUMAN,tr|E5RGM3|E5RGM3_HUMAN,tr|E5RJR5|E5RJR5_HUMAN,tr|E7ERH2|E7ERH2_HUMAN,tr|F8W8N3|F8W8N3_HUMAN" 5 1778.8958 1.01 37216 22553 3 1778.895723 593.9725 S-phase kinase-associated protein 1 OS=Homo sapiens OX=9606 GN=SKP1 PE=1 SV=2 4.23 3570.2 - 1.50E+06 - - - -0.0545 - 2.8 0.619 - 263.9 1 2 0 -0.0001 14 0 0 0 1.24E+07 1.23E+07 - - - 8.1775 1 221125_WJC_METTL3_EV_vs_WT_F03.22554.22554.2 1.21E-07 30-Dec K.TVSLLDENNVSSYLSK[136.11].N sp|P78527|PRKDC_HUMAN 1 1775.9033 0.23 37217 22554 2 1775.90536 888.9589 DNA-dependent protein kinase catalytic subunit OS=Homo sapiens OX=9606 GN=PRKDC PE=1 SV=3 4.37 3570.3 - 1.37E+06 - - - 1.1825 - 3.012 0.612 - 320.4 1 2 0 0.0021 16 0 0 0 3.85E+06 1.66E+07 - - - 6.2714 1 221125_WJC_METTL3_EV_vs_WT_F03.22555.22555.3 0.0275 28/80 R.LLSRPQDALEGVVLSPSLEAR.V sp|Q9NVI7|ATD3A_HUMAN 1 2249.2379 1.37 37218 22555 3 2249.2407 750.7533 ATPase family AAA domain-containing protein 3A OS=Homo sapiens OX=9606 GN=ATAD3A PE=1 SV=2 4.68 3570.4 - 1.30E+06 - - - 1.2244 - 4.301 0.438 - 859.5 1 2 0 0.0028 21 0 0 0 5.64E+07 4.11E+07 - - - 6.92 1 221125_WJC_METTL3_EV_vs_WT_F03.22556.22556.2 8.94E-06 13/28 L.SFDTNEQSLEQVFSK.Y "sp|Q14011|CIRBP_HUMAN,tr|K7ER40|K7ER40_HUMAN,tr|K7EQL0|K7EQL0_HUMAN,tr|K7ENX8|K7ENX8_HUMAN,tr|K7EJV1|K7EJV1_HUMAN,tr|K7EJV5|K7EJV5_HUMAN,tr|K7ELT6|K7ELT6_HUMAN,tr|K7EIF7|K7EIF7_HUMAN,tr|K7EMY9|K7EMY9_HUMAN,tr|K7EQX4|K7EQX4_HUMAN,tr|K7ELV6|K7ELV6_HUMAN,tr|K7EQR7|K7EQR7_HUMAN,tr|K7EPM4|K7EPM4_HUMAN,tr|K7ENN6|K7ENN6_HUMAN,tr|D6W5Y5|D6W5Y5_HUMAN" 15 1757.8108 2.22 37219 22556 2 1757.81331 879.9127 Cold-inducible RNA-binding protein OS=Homo sapiens OX=9606 GN=CIRBP PE=1 SV=1 4.14 3570.6 - 1.19E+06 - - - 1.4228 - 3.253 0.602 - 452.8 1 1 0 0.0025 15 0 0 0 1.78E+07 8.03E+06 - - - 6.3866 1 221125_WJC_METTL3_EV_vs_WT_F03.22558.22558.3 1.78E-05 21/80 R.LLSR[166.11]PQDALEGVVLSPSLEAR[166.11].V sp|Q9NVI7|ATD3A_HUMAN 1 2269.2545 1.37 37221 22558 3 2269.255648 757.4254 ATPase family AAA domain-containing protein 3A OS=Homo sapiens OX=9606 GN=ATAD3A PE=1 SV=2 4.68 3570.8 - 904057 - - - 0.5121 - 3.962 0.548 - 538.2 1 2 0 0.0012 21 0 0 0 5.64E+07 4.11E+07 - - - 7.95 1 221125_WJC_METTL3_EV_vs_WT_F03.22559.22559.3 0.000957 18/56 K.ASVITQVFHVPLEER.K "sp|Q00341|VIGLN_HUMAN,tr|C9JHZ8|C9JHZ8_HUMAN,tr|C9JZI8|C9JZI8_HUMAN,tr|C9JT62|C9JT62_HUMAN,tr|A0A024R4E5|A0A024R4E5_HUMAN,tr|C9JIZ1|C9JIZ1_HUMAN,tr|C9JES8|C9JES8_HUMAN,tr|C9J5E5|C9J5E5_HUMAN,tr|C9JK79|C9JK79_HUMAN,tr|C9JHS7|C9JHS7_HUMAN" 10 1723.9257 11.34 37222 22559 3 1723.9244 575.6492 Vigilin OS=Homo sapiens OX=9606 GN=HDLBP PE=1 SV=2 5.4 3570.9 - 882881 - - - -0.7657 - 3.11 0.434 - 540.2 1 2 0 -0.0013 15 0 0 0 6.99E+08 6.16E+07 - - - 6.339 1 221125_WJC_METTL3_EV_vs_WT_F03.22560.22560.4 1.44E-06 18/102 K.DYYFDSYAHFGIHEEMLK.D "sp|Q99873|ANM1_HUMAN,sp|Q9NR22|ANM8_HUMAN,tr|E9PQ98|E9PQ98_HUMAN,tr|E9PKG1|E9PKG1_HUMAN,tr|E9PMZ2|E9PMZ2_HUMAN,tr|E9PNR9|E9PNR9_HUMAN,tr|H0YDE4|H0YDE4_HUMAN,tr|E9PMW9|E9PMW9_HUMAN,tr|E9PIX6|E9PIX6_HUMAN" 9 2263.9885 5.44 37223 22560 4 2263.991507 567.0044 Protein arginine N-methyltransferase 1 OS=Homo sapiens OX=9606 GN=PRMT1 PE=1 SV=3 4.72 3571.1 - 858950 - - - 1.3476 - 2.555 0.537 - 116.7 1 2 0 0.0031 18 0 0 0 5.40E+06 9.93E+05 - - - 4.2205 0.8847 221125_WJC_METTL3_EV_vs_WT_F03.22562.22562.3 3.85 Nov-44 K.QPLWNHLLNYYK.E sp|Q92900|RENT1_HUMAN 1 1587.8198 1.39 37225 22562 3 1587.820365 530.2805 Regulator of nonsense transcripts 1 OS=Homo sapiens OX=9606 GN=UPF1 PE=1 SV=2 8.5 3571.3 - 740791 - - - 0.3571 - 1.83 0.013 - 132.8 1 2 0 0.0006 12 0 0 0 1.06E+07 7.63E+06 - - - 0.3599 0.9999 221125_WJC_METTL3_EV_vs_WT_F03.22563.22563.2 7.34E-10 16/34 K.SSGPTSLFAVTVAPPGAR.Q "sp|Q00839|HNRPU_HUMAN,tr|A0A1W2PP35|A0A1W2PP35_HUMAN,tr|A0A1W2PPS1|A0A1W2PPS1_HUMAN,tr|A0A1W2PP22|A0A1W2PP22_HUMAN,tr|A0A1X7SBS1|A0A1X7SBS1_HUMAN" 5 1713.905 1.09 37226 22563 2 1713.905272 857.9598 Heterogeneous nuclear ribonucleoprotein U OS=Homo sapiens OX=9606 GN=HNRNPU PE=1 SV=6 9.47 3571.4 - 684633 - - - 0.168 - 2.994 0.502 - 635.4 1 2 0 0.0003 18 0 0 0 8.72E+09 8.01E+09 - - - 5.4447 0.9999 221125_WJC_METTL3_EV_vs_WT_F03.22564.22564.3 0.000603 18/96 K.VVPAYVPTPIHPIFGGATHSAFGLK.A sp|Q96HA1|P121A_HUMAN 1 2575.3951 2.51 37227 22564 3 2575.397275 859.4723 Nuclear envelope pore membrane protein POM 121 OS=Homo sapiens OX=9606 GN=POM121 PE=1 SV=2 8.58 3571.6 - 669009 - - - 0.8387 - 2.532 0.423 - 172.2 1 2 0 0.0022 25 0 0 0 4.35E+06 1.73E+06 - - - 5.3927 0.9991 221125_WJC_METTL3_EV_vs_WT_F03.22566.22566.2 0.147 16-Jul K.GFGFVSFER.H "sp|Q9H361|PABP3_HUMAN,sp|P11940|PABP1_HUMAN,tr|A0A7I2YQE4|A0A7I2YQE4_HUMAN,tr|A0A7I2V649|A0A7I2V649_HUMAN,tr|H0YAR2|H0YAR2_HUMAN,tr|E7ERJ7|E7ERJ7_HUMAN,tr|A0A7I2YQ88|A0A7I2YQ88_HUMAN,tr|A0A087WTT1|A0A087WTT1_HUMAN,tr|H0YAP2|H0YAP2_HUMAN,tr|A0A7I2YQ90|A0A7I2YQ90_HUMAN,tr|A0A7I2V4N4|A0A7I2V4N4_HUMAN,tr|E7EQV3|E7EQV3_HUMAN" 12 1044.5029 5.48 37229 22566 2 1044.503851 523.2587 Polyadenylate-binding protein 3 OS=Homo sapiens OX=9606 GN=PABPC3 PE=1 SV=2 6 3571.8 - 435430 - - - 0.9287 - 1.628 0.303 - 102 1 2 0 0.001 9 0 0 0 3.79E+06 6.90E+05 - - - 2.6886 0.9999 221125_WJC_METTL3_EV_vs_WT_F03.22570.22570.3 1.39E-06 18/68 R.SLGETQLVLYGDVEELK[136.11]R[166.11].S sp|Q07065|CKAP4_HUMAN 1 2066.1015 1.85 37231 22570 3 2066.108923 689.7078 Cytoskeleton-associated protein 4 OS=Homo sapiens OX=9606 GN=CKAP4 PE=1 SV=2 4.41 3572.3 - 2.01E+06 - - - 3.6141 - 3.254 0.541 - 233.8 1 2 0 0.0075 18 0 0 0 3.74E+07 2.03E+07 - - - 7.5076 0.9998 221125_WJC_METTL3_EV_vs_WT_F03.22571.22571.2 5.65E-06 16/34 K.SSGPTSLFAVTVAPPGAR[166.11].Q "sp|Q00839|HNRPU_HUMAN,tr|A0A1W2PP35|A0A1W2PP35_HUMAN,tr|A0A1W2PPS1|A0A1W2PPS1_HUMAN,tr|A0A1W2PP22|A0A1W2PP22_HUMAN,tr|A0A1X7SBS1|A0A1X7SBS1_HUMAN" 5 1723.9133 1.09 37232 22571 2 1723.915959 862.9639 Heterogeneous nuclear ribonucleoprotein U OS=Homo sapiens OX=9606 GN=HNRNPU PE=1 SV=6 9.47 3572.4 - 1.80E+06 - - - 1.5691 - 3.003 0.489 - 658.8 1 2 0 0.0027 18 0 0 0 8.72E+09 8.01E+09 - - - 5.3554 0.9955 221125_WJC_METTL3_EV_vs_WT_F03.22572.22572.3 0.00405 19/80 C.LAISTPDAPATQDGVESLLQK[136.11].F "sp|Q86U44|MTA70_HUMAN,tr|B4E349|B4E349_HUMAN,tr|F5H6D8|F5H6D8_HUMAN,tr|H0YFV6|H0YFV6_HUMAN,tr|B4DTN4|B4DTN4_HUMAN" 5 2161.1358 0.05 37233 22572 3 2161.135978 721.3859 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 4.03 3572.4 - 6.56E+06 - - - 0.0921 - 3.225 0.425 - 426.9 1 1 0 0.0002 21 0 0 0 2.05E+06 4.34E+07 - - - 6.0855 1 221125_WJC_METTL3_EV_vs_WT_F03.22574.22574.3 9.10E-07 21/84 K.AVLSAEQLR[166.11]DEEVHAGLGELLR[166.11].S "sp|P50454|SERPH_HUMAN,tr|E9PNX1|E9PNX1_HUMAN,tr|E9PIG2|E9PIG2_HUMAN,tr|E9PPV6|E9PPV6_HUMAN,tr|E9PR70|E9PR70_HUMAN,tr|E9PMI5|E9PMI5_HUMAN,tr|E9PRS3|E9PRS3_HUMAN,tr|E9PJH8|E9PJH8_HUMAN,tr|E9PK86|E9PK86_HUMAN,tr|E9PQ34|E9PQ34_HUMAN" 10 2424.2876 1.16 37235 22574 3 2424.289954 809.1031 Serpin H1 OS=Homo sapiens OX=9606 GN=SERPINH1 PE=1 SV=2 4.57 3572.6 - 1.90E+06 - - - 0.9805 - 4.198 0.592 - 421.6 1 2 1 0.0024 22 0 0 0 1.92E+07 1.65E+07 - - - 8.5408 0.9861 221125_WJC_METTL3_EV_vs_WT_F03.22575.22575.3 8.65E-05 15/56 K.ALSAIADLLTNEHER.V "sp|O60716|CTND1_HUMAN,tr|A0A669KB62|A0A669KB62_HUMAN,tr|A0A804HJM1|A0A804HJM1_HUMAN,tr|A0A804HK15|A0A804HK15_HUMAN,tr|A0A669KB05|A0A669KB05_HUMAN,tr|C9JZR2|C9JZR2_HUMAN,tr|H0YC95|H0YC95_HUMAN,tr|A0A804HIL4|A0A804HIL4_HUMAN" 8 1651.8529 1.3 37236 22575 3 1651.850494 551.6249 Catenin delta-1 OS=Homo sapiens OX=9606 GN=CTNND1 PE=1 SV=1 4.65 3572.7 - 1.64E+06 - - - -1.4862 - 2.765 0.063 - 258 2 2 0 -0.0025 15 0 0 0 1.29E+07 9.93E+06 - - - 1.7562 0.9999 221125_WJC_METTL3_EV_vs_WT_F03.22576.22576.3 7.45E-07 Dec-44 R.MKIELFADVVPK.T "sp|O43447|PPIH_HUMAN,tr|A0A7I2V2H6|A0A7I2V2H6_HUMAN,tr|A0A7I2V343|A0A7I2V343_HUMAN,tr|A0A7I2V5V0|A0A7I2V5V0_HUMAN,tr|C9JQD4|C9JQD4_HUMAN" 5 1388.7738 2.83 37237 22576 3 1388.773611 463.9319 Peptidyl-prolyl cis-trans isomerase H OS=Homo sapiens OX=9606 GN=PPIH PE=1 SV=1 5.82 3572.8 - 1.54E+06 - - - -0.1066 - 2.452 0.489 - 181.3 1 2 1 -0.0001 12 0 0 0 3.57E+07 1.26E+07 - - - 6.4779 1 221125_WJC_METTL3_EV_vs_WT_F03.22577.22577.3 5.30E-05 18/56 K.ALSAIADLLTNEHER[166.11].V "sp|O60716|CTND1_HUMAN,tr|A0A669KB62|A0A669KB62_HUMAN,tr|A0A804HJM1|A0A804HJM1_HUMAN,tr|A0A804HK15|A0A804HK15_HUMAN,tr|A0A669KB05|A0A669KB05_HUMAN,tr|C9JZR2|C9JZR2_HUMAN,tr|H0YC95|H0YC95_HUMAN,tr|A0A804HIL4|A0A804HIL4_HUMAN" 8 1661.8612 1.9 37238 22577 3 1661.861095 554.961 Catenin delta-1 OS=Homo sapiens OX=9606 GN=CTNND1 PE=1 SV=1 4.65 3572.9 - 1.34E+06 - - - -0.0746 - 3.287 0.442 - 437.4 1 2 0 -0.0001 15 0 0 0 1.92E+07 1.01E+07 - - - 6.5729 1 221125_WJC_METTL3_EV_vs_WT_F03.22578.22578.2 6.34E-13 21/32 K.DGLNDDDFEPYLSPQAR.P "sp|Q9Y5A9|YTHD2_HUMAN,tr|S4R3J8|S4R3J8_HUMAN" 2 1950.8595 1.72 37239 22578 2 1950.861809 976.4371 YTH domain-containing family protein 2 OS=Homo sapiens OX=9606 GN=YTHDF2 PE=1 SV=2 3.71 3573 - 1.24E+06 - - - 1.158 - 3.56 0.728 - 943.8 1 1 0 0.0023 17 0 0 0 4.79E+08 2.79E+08 - - - 7.5391 0.9974 221125_WJC_METTL3_EV_vs_WT_F03.22581.22581.3 0.00109 17/64 K.DGLNDDDFEPYLSPQAR.P "sp|Q9Y5A9|YTHD2_HUMAN,tr|S4R3J8|S4R3J8_HUMAN" 2 1950.8595 1.77 37242 22581 3 1950.860535 651.2938 YTH domain-containing family protein 2 OS=Homo sapiens OX=9606 GN=YTHDF2 PE=1 SV=2 3.71 3573.3 - 1.05E+06 - - - 0.5049 - 2.382 0.542 - 377.4 1 1 0 0.001 17 0 0 0 2.81E+08 1.59E+08 - - - 6.7752 0.9998 221125_WJC_METTL3_EV_vs_WT_F03.22582.22582.3 5.94E-05 17/44 R.GFK[136.11]DQIYDIFQK[136.11].L "sp|P60842|IF4A1_HUMAN,tr|J3KTB5|J3KTB5_HUMAN,tr|J3KT12|J3KT12_HUMAN,tr|J3QS69|J3QS69_HUMAN,tr|J3QL43|J3QL43_HUMAN,tr|J3KTN0|J3KTN0_HUMAN,tr|J3KSZ0|J3KSZ0_HUMAN,tr|J3QR64|J3QR64_HUMAN" 8 1516.7897 1.11 37243 22582 3 1516.79005 506.6038 Eukaryotic initiation factor 4A-I OS=Homo sapiens OX=9606 GN=EIF4A1 PE=1 SV=1 5.96 3573.4 - 1.02E+06 - - - 0.2439 - 2.419 0.434 - 239.5 1 2 1 0.0004 12 0 0 0 3.66E+07 3.29E+07 - - - 5.8271 1 221125_WJC_METTL3_EV_vs_WT_F03.22583.22583.2 1.84E-11 20/32 K.DGLNDDDFEPYLSPQAR[166.11].P "sp|Q9Y5A9|YTHD2_HUMAN,tr|S4R3J8|S4R3J8_HUMAN" 2 1960.8678 1.72 37244 22583 2 1960.867721 981.4412 YTH domain-containing family protein 2 OS=Homo sapiens OX=9606 GN=YTHDF2 PE=1 SV=2 3.71 3573.5 - 791976 - - - -0.0505 - 3.403 0.723 - 847.2 1 1 0 -0.0001 17 0 0 0 4.79E+08 2.79E+08 - - - 7.3919 0.9995 221125_WJC_METTL3_EV_vs_WT_F03.22584.22584.3 1.63E-05 Oct-44 R.MK[136.11]IELFADVVPK[136.11].T "sp|O43447|PPIH_HUMAN,tr|A0A7I2V2H6|A0A7I2V2H6_HUMAN,tr|A0A7I2V343|A0A7I2V343_HUMAN,tr|A0A7I2V5V0|A0A7I2V5V0_HUMAN,tr|C9JQD4|C9JQD4_HUMAN" 5 1404.8022 2.83 37245 22584 3 1404.801792 469.2747 Peptidyl-prolyl cis-trans isomerase H OS=Homo sapiens OX=9606 GN=PPIH PE=1 SV=1 5.82 3573.6 - 629096 - - - -0.2612 - 2.149 0.396 - 101 1 2 1 -0.0004 12 0 0 0 3.57E+07 1.26E+07 - - - 5.0754 0.9989 221125_WJC_METTL3_EV_vs_WT_F03.22586.22586.3 0.000548 Nov-96 K.YGGPPPDSVYSGVQPGIGTEVFVGK[136.11].L "sp|O43390|HNRPR_HUMAN,tr|A0A6Q8PEX7|A0A6Q8PEX7_HUMAN" 2 2514.2522 1.7 37247 22586 3 2514.254086 839.0913 Heterogeneous nuclear ribonucleoprotein R OS=Homo sapiens OX=9606 GN=HNRNPR PE=1 SV=1 4.37 3573.9 - 530740 - - - 0.7477 - 2.175 0.261 - 84 1 2 0 0.0019 25 0 0 0 1.19E+08 6.97E+07 - - - 3.237 0.9999 221125_WJC_METTL3_EV_vs_WT_F03.22588.22588.4 0.000321 Sep-90 R.DYLHLPPEIVPATLR[166.11]R[166.11].S "sp|P46783|RS10_HUMAN,tr|A0A2R8Y6L3|A0A2R8Y6L3_HUMAN,tr|F6U211|F6U211_HUMAN,tr|A0A1W2PQS6|A0A1W2PQS6_HUMAN,tr|A0A2R8YFH6|A0A2R8YFH6_HUMAN,tr|A0A2R8Y7H1|A0A2R8Y7H1_HUMAN,tr|S4R435|S4R435_HUMAN" 7 1909.0689 0.86 37249 22588 4 1909.067038 478.2745 40S ribosomal protein S10 OS=Homo sapiens OX=9606 GN=RPS10 PE=1 SV=1 6.75 3574.2 - 450210 - - - -0.9528 - 1.921 0.429 - 64.9 1 2 0 -0.0018 16 0 0 0 5.84E+06 6.79E+06 - - - 3.1895 0.931 221125_WJC_METTL3_EV_vs_WT_F03.22590.22590.4 0.0232 11/126 K.AVLSAEQLR[166.11]DEEVHAGLGELLR[166.11].S "sp|P50454|SERPH_HUMAN,tr|E9PNX1|E9PNX1_HUMAN,tr|E9PIG2|E9PIG2_HUMAN,tr|E9PPV6|E9PPV6_HUMAN,tr|E9PR70|E9PR70_HUMAN,tr|E9PMI5|E9PMI5_HUMAN,tr|E9PRS3|E9PRS3_HUMAN,tr|E9PJH8|E9PJH8_HUMAN,tr|E9PK86|E9PK86_HUMAN,tr|E9PQ34|E9PQ34_HUMAN" 10 2424.2876 1.59 37250 22590 4 2424.289526 607.0792 Serpin H1 OS=Homo sapiens OX=9606 GN=SERPINH1 PE=1 SV=2 4.57 3574.4 - 9.12E+06 - - - 0.8039 - 1.801 0.177 - 69.1 1 2 1 0.0019 22 0 0 0 8.17E+07 5.13E+07 - - - 0.9586 1 221125_WJC_METTL3_EV_vs_WT_F03.22592.22592.3 1.75E-08 16/60 R.RFDEILEASDGIMVAR.G "sp|P14618|KPYM_HUMAN,tr|B4DNK4|B4DNK4_HUMAN,tr|A0A804F6T5|A0A804F6T5_HUMAN,tr|H3BTN5|H3BTN5_HUMAN,tr|H3BR70|H3BR70_HUMAN,tr|A0A804F729|A0A804F729_HUMAN" 6 1820.9091 9.05 37251 22592 3 1820.907943 607.977 Pyruvate kinase PKM OS=Homo sapiens OX=9606 GN=PKM PE=1 SV=4 4.32 3574.6 - 1.01E+07 - - - -0.6266 - 3.188 0.553 - 445.1 1 2 0 -0.0011 16 0 0 0 3.82E+08 4.22E+07 - - - 7.6799 1 221125_WJC_METTL3_EV_vs_WT_F03.22593.22593.3 1.92E-07 Dec-72 R.GSYGDLGGPIITTQVTIPK.D "sp|P61978|HNRPK_HUMAN,tr|S4R359|S4R359_HUMAN,tr|Q5T6W2|Q5T6W2_HUMAN" 3 1916.0255 1.27 37252 22593 3 1916.026592 639.6824 Heterogeneous nuclear ribonucleoprotein K OS=Homo sapiens OX=9606 GN=HNRNPK PE=1 SV=1 5.83 3574.6 - 7.00E+06 - - - 0.5731 - 2.351 0.524 - 115 1 2 0 0.0011 19 0 0 0 2.26E+08 1.78E+08 - - - 6.482 1 221125_WJC_METTL3_EV_vs_WT_F03.22595.22595.3 8.50E-09 15/60 R.R[166.11]FDEILEASDGIMVAR[166.11].G "sp|P14618|KPYM_HUMAN,tr|B4DNK4|B4DNK4_HUMAN,tr|A0A804F6T5|A0A804F6T5_HUMAN,tr|H3BTN5|H3BTN5_HUMAN,tr|H3BR70|H3BR70_HUMAN,tr|A0A804F729|A0A804F729_HUMAN" 6 1840.9256 6.98 37254 22595 3 1840.923243 614.6492 Pyruvate kinase PKM OS=Homo sapiens OX=9606 GN=PKM PE=1 SV=4 4.32 3574.7 - 3.65E+06 - - - -1.2934 - 3.425 0.589 - 457.1 1 2 0 -0.0024 16 0 0 0 2.75E+08 3.94E+07 - - - 8.2649 0.9999 221125_WJC_METTL3_EV_vs_WT_F03.22597.22597.3 9.25E-08 19/68 K.LVINGNPITIFQERDPSK.L sp|P04406|G3P_HUMAN 1 2040.1004 1.15 37256 22597 3 2040.105096 681.0407 Glyceraldehyde-3-phosphate dehydrogenase OS=Homo sapiens OX=9606 GN=GAPDH PE=1 SV=3 6.07 3574.9 - 1.34E+06 - - - 2.3067 - 3.538 0.552 - 380.8 1 2 1 0.0047 18 0 0 0 7.92E+08 6.87E+08 - - - 7.8393 1 221125_WJC_METTL3_EV_vs_WT_F03.22599.22599.3 2.15E-06 19/96 K.YGGPPPDSVYSGVQPGIGTEVFVGK.L "sp|O43390|HNRPR_HUMAN,tr|A0A6Q8PEX7|A0A6Q8PEX7_HUMAN" 2 2506.238 1.66 37258 22599 3 2506.238576 836.4199 Heterogeneous nuclear ribonucleoprotein R OS=Homo sapiens OX=9606 GN=HNRNPR PE=1 SV=1 4.37 3575.2 - 1.28E+06 - - - 0.2274 - 2.848 0.499 - 222.8 1 2 0 0.0006 25 0 0 0 1.15E+08 6.95E+07 - - - 6.5111 1 221125_WJC_METTL3_EV_vs_WT_F03.22600.22600.3 1.43E-08 13/60 K.TLSHNLLVSEVYNQLK[136.11].F "sp|Q13620|CUL4B_HUMAN,tr|A0A7P0T8P8|A0A7P0T8P8_HUMAN,tr|A0A669KAX4|A0A669KAX4_HUMAN,tr|K4DI93|K4DI93_HUMAN,tr|A0A7P0T9C8|A0A7P0T9C8_HUMAN,tr|A0A7P0T954|A0A7P0T954_HUMAN,tr|A0A7P0T9L3|A0A7P0T9L3_HUMAN,tr|A0A7P0TAQ3|A0A7P0TAQ3_HUMAN" 8 1865.0138 0.78 37259 22600 3 1865.015553 622.6785 Cullin-4B OS=Homo sapiens OX=9606 GN=CUL4B PE=1 SV=4 6.41 3575.3 - 1.19E+06 - - - 0.933 - 2.895 0.567 - 271.6 1 2 0 0.0017 16 0 0 0 4.93E+06 6.36E+06 - - - 7.5885 0.9947 221125_WJC_METTL3_EV_vs_WT_F03.22601.22601.2 4.74E-06 16/28 L.SFDTNEQSLEQVFSK[136.11].Y "sp|Q14011|CIRBP_HUMAN,tr|K7ER40|K7ER40_HUMAN,tr|K7EQL0|K7EQL0_HUMAN,tr|K7ENX8|K7ENX8_HUMAN,tr|K7EJV1|K7EJV1_HUMAN,tr|K7EJV5|K7EJV5_HUMAN,tr|K7ELT6|K7ELT6_HUMAN,tr|K7EIF7|K7EIF7_HUMAN,tr|K7EMY9|K7EMY9_HUMAN,tr|K7EQX4|K7EQX4_HUMAN,tr|K7ELV6|K7ELV6_HUMAN,tr|K7EQR7|K7EQR7_HUMAN,tr|K7EPM4|K7EPM4_HUMAN,tr|K7ENN6|K7ENN6_HUMAN,tr|D6W5Y5|D6W5Y5_HUMAN" 15 1765.825 2.22 37260 22601 2 1765.825463 883.9198 Cold-inducible RNA-binding protein OS=Homo sapiens OX=9606 GN=CIRBP PE=1 SV=1 4.14 3575.4 - 912622 - - - 0.2571 - 2.861 0.537 - 622.3 1 1 0 0.0005 15 0 0 0 1.78E+07 8.03E+06 - - - 5.5915 0.9997 221125_WJC_METTL3_EV_vs_WT_F03.22602.22602.3 0.000157 14/60 K.TLSHNLLVSEVYNQLK.F "sp|Q13620|CUL4B_HUMAN,tr|A0A7P0T8P8|A0A7P0T8P8_HUMAN,tr|A0A669KAX4|A0A669KAX4_HUMAN,tr|K4DI93|K4DI93_HUMAN,tr|A0A7P0T9C8|A0A7P0T9C8_HUMAN,tr|A0A7P0T954|A0A7P0T954_HUMAN,tr|A0A7P0T9L3|A0A7P0T9L3_HUMAN,tr|A0A7P0TAQ3|A0A7P0TAQ3_HUMAN" 8 1856.9996 0.66 37261 22602 3 1857.002023 620.0071 Cullin-4B OS=Homo sapiens OX=9606 GN=CUL4B PE=1 SV=4 6.41 3575.5 - 765684 - - - 1.2978 - 2.558 0.32 - 216.5 1 2 0 0.0024 16 0 0 0 4.00E+06 6.08E+06 - - - 4.5169 0.9994 221125_WJC_METTL3_EV_vs_WT_F03.22606.22606.2 0.0415 18-Sep R.FEELNADLFR[166.11].G "sp|P54652|HSP72_HUMAN,sp|P11142|HSP7C_HUMAN,tr|E9PNE6|E9PNE6_HUMAN,tr|A8K7Q2|A8K7Q2_HUMAN,tr|E9PKE3|E9PKE3_HUMAN,tr|E9PN89|E9PN89_HUMAN" 6 1262.6171 0.17 37264 22606 2 1262.617973 632.3158 Heat shock-related 70 kDa protein 2 OS=Homo sapiens OX=9606 GN=HSPA2 PE=1 SV=1 4.14 3576.1 - 1.73E+06 - - - 0.7136 - 2.029 0.262 - 278.3 1 2 0 0.0009 10 0 0 0 4.62E+06 2.69E+07 - - - 2.9508 1 221125_WJC_METTL3_EV_vs_WT_F03.22608.22608.2 1.57E-05 13/26 K.GFGFVDFNSEEDAK.A "sp|P19338|NUCL_HUMAN,tr|A0A7I2V699|A0A7I2V699_HUMAN,tr|A0A7I2V3F3|A0A7I2V3F3_HUMAN,tr|A0A7I2V428|A0A7I2V428_HUMAN,tr|H7BY16|H7BY16_HUMAN,tr|A0A7I2V5M5|A0A7I2V5M5_HUMAN,tr|C9JLB1|C9JLB1_HUMAN" 7 1560.6733 1.05 37265 22608 2 1560.673759 781.3439 Nucleolin OS=Homo sapiens OX=9606 GN=NCL PE=1 SV=3 3.92 3576.3 - 5.12E+06 - - - 0.3242 - 2.755 0.587 - 566.2 1 2 0 0.0005 14 0 0 0 4.92E+08 4.70E+08 - - - 5.9195 0.9999 221125_WJC_METTL3_EV_vs_WT_F03.22610.22610.3 9.99E-05 15/68 K.SSGPTSLFAVTVAPPGAR.Q "sp|Q00839|HNRPU_HUMAN,tr|A0A1W2PP35|A0A1W2PP35_HUMAN,tr|A0A1W2PPS1|A0A1W2PPS1_HUMAN,tr|A0A1W2PP22|A0A1W2PP22_HUMAN,tr|A0A1X7SBS1|A0A1X7SBS1_HUMAN" 5 1713.905 0.99 37267 22610 3 1713.905799 572.3089 Heterogeneous nuclear ribonucleoprotein U OS=Homo sapiens OX=9606 GN=HNRNPU PE=1 SV=6 9.47 3576.4 - 4.11E+06 - - - 0.4755 - 2.711 0.433 - 182.8 1 2 0 0.0008 18 0 0 0 2.06E+09 2.07E+09 - - - 5.8507 1 221125_WJC_METTL3_EV_vs_WT_F03.22612.22612.3 1.92E-08 21/68 K.LVINGNPITIFQER[166.11]DPSK[136.11].L sp|P04406|G3P_HUMAN 1 2058.1229 1.15 37269 22612 3 2058.124624 687.0482 Glyceraldehyde-3-phosphate dehydrogenase OS=Homo sapiens OX=9606 GN=GAPDH PE=1 SV=3 6.07 3576.5 - 3.04E+06 - - - 0.8571 - 3.854 0.598 - 471 1 2 1 0.0018 18 0 0 0 7.92E+08 6.87E+08 - - - 8.566 0.9998 221125_WJC_METTL3_EV_vs_WT_F03.22614.22614.2 4.25E-06 13/26 K.ETLTFPPEVPISEK.A sp|Q15208|STK38_HUMAN 1 1585.8239 19.17 37271 22614 2 1585.823221 793.9192 Serine\threonine-protein kinase 38 OS=Homo sapiens OX=9606 GN=STK38 PE=1 SV=1 4.25 3576.7 - 1.87E+06 - - - -0.4534 - 2.108 0.466 - 309.7 1 2 0 -0.0007 14 0 0 0 9.02E+07 4.71E+06 - - - 4.354 1 221125_WJC_METTL3_EV_vs_WT_F03.22615.22615.3 3.55E-15 23/108 R.AAAMLPTVGEGYGYGPESELSQASAATR.N sp|Q9BQ04|RBM4B_HUMAN 1 2783.3072 1.64 37272 22615 3 2783.30969 928.7764 RNA-binding protein 4B OS=Homo sapiens OX=9606 GN=RBM4B PE=1 SV=1 4.25 3576.8 - 1.69E+06 - - - 0.886 - 4.332 0.722 - 453.2 1 2 0 0.0025 28 0 0 0 2.49E+08 1.51E+08 - - - 9.9617 0.9605 221125_WJC_METTL3_EV_vs_WT_F03.22618.22618.3 0.00915 Oct-56 R.IEINFPAEYPFKPPK.L sp|P68036|UB2L3_HUMAN 1 1788.9451 1.77 37275 22618 3 1788.947825 597.3223 Ubiquitin-conjugating enzyme E2 L3 OS=Homo sapiens OX=9606 GN=UBE2L3 PE=1 SV=1 6.14 3577.2 - 611318 - - - 1.5467 - 2.101 0.066 - 110.3 1 2 0 0.0028 15 0 0 0 6.35E+07 3.58E+07 - - - 1.2123 1 221125_WJC_METTL3_EV_vs_WT_F03.22620.22620.2 2.10E-11 18/40 R.AILGSYDSELTPAEYSPQLTR.R "sp|Q9Y6D9|MD1L1_HUMAN,tr|C9JX80|C9JX80_HUMAN,tr|C9J9H5|C9J9H5_HUMAN" 3 2310.138 3.95 37277 22620 2 2310.137277 1156.0763 Mitotic spindle assembly checkpoint protein MAD1 OS=Homo sapiens OX=9606 GN=MAD1L1 PE=1 SV=2 4.14 3577.4 - 532291 - - - -0.2944 - 3.636 0.685 - 438.9 1 2 0 -0.0007 21 0 0 0 4.95E+06 1.25E+06 - - - 7.2739 0.9998 221125_WJC_METTL3_EV_vs_WT_F03.22625.22625.4 0.000536 Dec-90 R.DYLHLPPEIVPATLRR.S "sp|P46783|RS10_HUMAN,tr|A0A2R8Y6L3|A0A2R8Y6L3_HUMAN,tr|F6U211|F6U211_HUMAN,tr|A0A1W2PQS6|A0A1W2PQS6_HUMAN,tr|A0A2R8YFH6|A0A2R8YFH6_HUMAN,tr|A0A2R8Y7H1|A0A2R8Y7H1_HUMAN,tr|S4R435|S4R435_HUMAN" 7 1889.0523 1.49 37281 22625 4 1889.056344 473.2704 40S ribosomal protein S10 OS=Homo sapiens OX=9606 GN=RPS10 PE=1 SV=1 6.75 3578.1 - 448013 - - - 2.1318 - 2.347 0.411 - 99.6 1 2 0 0.004 16 0 0 0 5.92E+06 3.98E+06 - - - 3.1028 1 221125_WJC_METTL3_EV_vs_WT_F03.22628.22628.2 2.81E-07 26-Dec K.GFGFVDFNSEEDAK[136.11].A "sp|P19338|NUCL_HUMAN,tr|A0A7I2V699|A0A7I2V699_HUMAN,tr|A0A7I2V3F3|A0A7I2V3F3_HUMAN,tr|A0A7I2V428|A0A7I2V428_HUMAN,tr|H7BY16|H7BY16_HUMAN,tr|A0A7I2V5M5|A0A7I2V5M5_HUMAN,tr|C9JLB1|C9JLB1_HUMAN" 7 1568.6875 1.05 37283 22628 2 1568.683943 785.351 Nucleolin OS=Homo sapiens OX=9606 GN=NCL PE=1 SV=3 3.92 3578.3 - 1.34E+07 - - - -2.2375 - 2.717 0.577 - 444.5 1 2 0 -0.0035 14 0 0 0 4.92E+08 4.70E+08 - - - 5.8099 1 221125_WJC_METTL3_EV_vs_WT_F03.22629.22629.3 5.57E-11 21/80 R.SYLPYPAPEGIAVSPLSLHGK.G "sp|Q6W2J9|BCOR_HUMAN,tr|H7BZ37|H7BZ37_HUMAN,tr|A1A564|A1A564_HUMAN,tr|H7C2V9|H7C2V9_HUMAN,tr|H7BYY2|H7BYY2_HUMAN,tr|H7C231|H7C231_HUMAN" 6 2195.1627 2.03 37284 22629 3 2195.164056 732.7282 BCL-6 corepressor OS=Homo sapiens OX=9606 GN=BCOR PE=1 SV=1 6.47 3578.4 - 1.03E+07 - - - 0.6378 - 3.527 0.657 - 345.1 1 2 0 0.0014 21 0 0 0 8.94E+07 4.41E+07 - - - 8.8864 0.9999 221125_WJC_METTL3_EV_vs_WT_F03.22630.22630.2 1.98E-11 16/30 K.NAEPLINLDVNNPDFK.A "sp|Q9Y224|RTRAF_HUMAN,tr|G3V4C6|G3V4C6_HUMAN,tr|H0YJB9|H0YJB9_HUMAN" 3 1811.9054 2.82 37285 22630 2 1811.90466 906.96 "RNA transcription, translation and transport factor protein OS=Homo sapiens OX=9606 GN=RTRAF PE=1 SV=1" 4.03 3578.5 - 1.66E+06 - - - -0.3963 - 3.21 0.431 - 815.9 1 2 0 -0.0007 16 0 0 0 1.76E+08 6.25E+07 - - - 5.0915 1 221125_WJC_METTL3_EV_vs_WT_F03.22633.22633.2 2.25E-12 15/30 K.DSDGQVFGALASEPLK[136.11].V "sp|Q8N573|OXR1_HUMAN,tr|E9PLW2|E9PLW2_HUMAN,tr|H0YC07|H0YC07_HUMAN" 3 1640.8137 2.16 37288 22633 2 1640.811778 821.4141 Oxidation resistance protein 1 OS=Homo sapiens OX=9606 GN=OXR1 PE=1 SV=2 4.03 3578.9 - 974624 - - - -1.1811 - 3.154 0.653 - 683.7 1 2 0 -0.0019 16 0 0 0 2.25E+07 1.04E+07 - - - 6.6875 1 221125_WJC_METTL3_EV_vs_WT_F03.22635.22635.2 1.18E-08 16/26 Q.AQISALEEQLQQIR.A "sp|P13645|K1C10_HUMAN,tr|A0A1B0GVI3|A0A1B0GVI3_HUMAN" 2 1625.8737 1278.18 37290 22635 2 1625.872468 813.9441 "Keratin, type I cytoskeletal 10 OS=Homo sapiens OX=9606 GN=KRT10 PE=1 SV=6" 4.53 3579.1 - 700853 - - - -0.7479 - 3.399 0.572 - 820.4 1 1 0 -0.0012 14 0 0 0 4.87E+08 3.81E+05 - - - 6.3357 0.9999 221125_WJC_METTL3_EV_vs_WT_F03.22636.22636.3 0.000747 13/48 R.IDILDSALLRPGR.L sp|P62195|PRS8_HUMAN 1 1437.8304 0.75 37291 22636 3 1437.830219 480.2841 26S proteasome regulatory subunit 8 OS=Homo sapiens OX=9606 GN=PSMC5 PE=1 SV=1 5.96 3579.3 - 686508 - - - -0.1002 - 2.458 0.347 - 242 1 2 0 -0.0001 13 0 0 0 1.03E+07 1.37E+07 - - - 4.8471 0.9996 221125_WJC_METTL3_EV_vs_WT_F03.22638.22638.3 4.82E-07 15/60 R.LQQTQAQVDEVVDIMR.V "sp|P63027|VAMP2_HUMAN,tr|F8WCA0|F8WCA0_HUMAN,tr|L7N2F9|L7N2F9_HUMAN,tr|J3QRU4|J3QRU4_HUMAN" 4 1871.9411 1.48 37293 22638 3 1871.934299 624.9876 Vesicle-associated membrane protein 2 OS=Homo sapiens OX=9606 GN=VAMP2 PE=1 SV=3 4.03 3579.5 - 496719 - - - -3.6395 - 2.63 0.403 - 283.6 1 2 0 -0.0068 16 0 0 0 4.24E+06 2.87E+06 - - - 5.5123 0.9978 221125_WJC_METTL3_EV_vs_WT_F03.22645.22645.3 3.95E-06 14/52 Q.AQISALEEQLQQIR.A "sp|P13645|K1C10_HUMAN,tr|A0A1B0GVI3|A0A1B0GVI3_HUMAN" 2 1625.8737 3406.37 37298 22645 3 1625.87281 542.9652 "Keratin, type I cytoskeletal 10 OS=Homo sapiens OX=9606 GN=KRT10 PE=1 SV=6" 4.53 3580.2 - 4.02E+06 - - - -0.5376 - 2.942 0.502 - 318.5 1 1 0 -0.0009 14 0 0 0 4.45E+08 1.31E+05 - - - 7.0043 1 221125_WJC_METTL3_EV_vs_WT_F03.22646.22646.3 1.09E-10 16/60 K.NAEPLINLDVNNPDFK.A "sp|Q9Y224|RTRAF_HUMAN,tr|G3V4C6|G3V4C6_HUMAN,tr|H0YJB9|H0YJB9_HUMAN" 3 1811.9054 2.1 37299 22646 3 1811.906734 604.9757 "RNA transcription, translation and transport factor protein OS=Homo sapiens OX=9606 GN=RTRAF PE=1 SV=1" 4.03 3580.3 - 2.75E+06 - - - 0.7484 - 3.114 0.504 - 420.2 1 2 0 0.0014 16 0 0 0 7.32E+07 3.49E+07 - - - 7.0733 1 221125_WJC_METTL3_EV_vs_WT_F03.22647.22647.3 3.15E-11 25/76 K.LSEVLQAVTDHDIPQQLVER.L "sp|Q93009|UBP7_HUMAN,tr|A0A669KBL1|A0A669KBL1_HUMAN,tr|H3BND8|H3BND8_HUMAN" 3 2289.1965 12.59 37300 22647 3 2289.196759 764.0728 Ubiquitin carboxyl-terminal hydrolase 7 OS=Homo sapiens OX=9606 GN=USP7 PE=1 SV=2 4.31 3580.4 - 2.44E+06 - - - 0.1241 - 4.345 0.593 - 719.5 1 2 0 0.0003 20 0 0 0 3.96E+07 3.14E+06 - - - 8.7152 1 221125_WJC_METTL3_EV_vs_WT_F03.22650.22650.2 2.09E-09 17/34 K.GIVDQSQQAYQEAFEISK.K "sp|P63104|1433Z_HUMAN,tr|H0YB80|H0YB80_HUMAN,tr|E7EX29|E7EX29_HUMAN,tr|B7Z2E6|B7Z2E6_HUMAN,tr|B0AZS6|B0AZS6_HUMAN" 5 2039.98 1.23 37303 22650 2 2039.97937 1020.9973 14-3-3 protein zeta\delta OS=Homo sapiens OX=9606 GN=YWHAZ PE=1 SV=1 4.14 3580.7 - 1.73E+06 - - - -0.3088 - 3.837 0.578 - 930.6 1 2 0 -0.0006 18 0 0 0 4.49E+07 3.65E+07 - - - 6.6159 1 221125_WJC_METTL3_EV_vs_WT_F03.22651.22651.3 6.03E-07 19/64 R.VYAILTHGIFSGPAISR.L "sp|P60891|PRPS1_HUMAN,sp|P11908|PRPS2_HUMAN,sp|P21108|PRPS3_HUMAN,tr|A0A2R8Y7H4|A0A2R8Y7H4_HUMAN,tr|B1ALA9|B1ALA9_HUMAN,tr|A0A6Q8PGP2|A0A6Q8PGP2_HUMAN,tr|H7C540|H7C540_HUMAN,tr|A0A0A0MRQ9|A0A0A0MRQ9_HUMAN,tr|A0A0B4J207|A0A0B4J207_HUMAN" 9 1800.9887 1.13 37304 22651 3 1800.991454 601.3368 Ribose-phosphate pyrophosphokinase 1 OS=Homo sapiens OX=9606 GN=PRPS1 PE=1 SV=2 8.73 3580.8 - 1.50E+06 - - - 1.5547 - 3.177 0.542 - 319.5 1 2 0 0.0028 17 0 0 0 1.51E+07 1.33E+07 - - - 7.5022 1 221125_WJC_METTL3_EV_vs_WT_F03.22652.22652.2 5.87E-07 20/34 K.GIVDQSQQAYQEAFEISK[136.11].K "sp|P63104|1433Z_HUMAN,tr|H0YB80|H0YB80_HUMAN,tr|E7EX29|E7EX29_HUMAN,tr|B7Z2E6|B7Z2E6_HUMAN,tr|B0AZS6|B0AZS6_HUMAN" 5 2047.9942 1.23 37305 22652 2 2047.992778 1025.0044 14-3-3 protein zeta\delta OS=Homo sapiens OX=9606 GN=YWHAZ PE=1 SV=1 4.14 3580.9 - 1.44E+06 - - - -0.6943 - 4.112 0.68 - 1511.9 1 2 0 -0.0014 18 0 0 0 4.49E+07 3.65E+07 - - - 7.5392 1 221125_WJC_METTL3_EV_vs_WT_F03.22654.22654.2 1.70E-07 14/28 K.LEFDFTEDTGNIEAR.K "sp|O75410|TACC1_HUMAN,tr|E7EVI4|E7EVI4_HUMAN,tr|E5RFM9|E5RFM9_HUMAN,tr|R4GMT7|R4GMT7_HUMAN,tr|H0YAY0|H0YAY0_HUMAN,tr|E7ET87|E7ET87_HUMAN" 6 1755.7952 2.09 37307 22654 2 1755.793116 878.9049 Transforming acidic coiled-coil-containing protein 1 OS=Homo sapiens OX=9606 GN=TACC1 PE=1 SV=2 3.83 3581.2 - 942239 - - - -1.1636 - 2.953 0.548 - 719.8 1 2 0 -0.002 15 0 0 0 1.66E+07 7.95E+06 - - - 5.7501 1 221125_WJC_METTL3_EV_vs_WT_F03.22659.22659.3 2.94E-13 24/108 R.AAAMLPTVGEGYGYGPESELSQASAATR[166.11].N sp|Q9BQ04|RBM4B_HUMAN 1 2793.3155 1.64 37310 22659 3 2793.311852 932.1124 RNA-binding protein 4B OS=Homo sapiens OX=9606 GN=RBM4B PE=1 SV=1 4.25 3581.7 - 4.95E+06 - - - -1.3038 - 4.241 0.698 - 512.5 1 2 0 -0.0036 28 0 0 0 2.49E+08 1.51E+08 - - - 9.645 0.9999 221125_WJC_METTL3_EV_vs_WT_F03.22671.22671.2 4.88E-06 20-Oct K.GTNYLADVFEK.K sp|P31151|S10A7_HUMAN 1 1255.6085 38.11 37320 22671 2 1255.607557 628.8115 Protein S100-A7 OS=Homo sapiens OX=9606 GN=S100A7 PE=1 SV=4 4.37 3582.9 - 8.24E+06 - - - -0.7255 - 2.261 0.487 - 406.2 1 2 0 -0.0009 11 0 0 0 2.12E+08 5.57E+06 - - - 4.8446 0.9998 221125_WJC_METTL3_EV_vs_WT_F03.22672.22672.3 0.00227 14/76 R.NAALNTIVTVYNVHGDQVFK[136.11].L sp|Q14008|CKAP5_HUMAN 1 2210.1575 0.62 37321 22672 3 2210.1561 737.7264 Cytoskeleton-associated protein 5 OS=Homo sapiens OX=9606 GN=CKAP5 PE=1 SV=3 6.74 3582.9 - 2.20E+06 - - - -0.6411 - 2.547 0.331 - 217.9 1 2 0 -0.0014 20 0 0 0 1.05E+07 1.70E+07 - - - 4.4981 0.9997 221125_WJC_METTL3_EV_vs_WT_F03.22680.22680.3 6.40E-09 20/76 R.IKAEYEGDGIPTVFVAVAGR.S "sp|P22234|PUR6_HUMAN,tr|D6RF62|D6RF62_HUMAN,tr|E9PBS1|E9PBS1_HUMAN" 3 2091.1001 1.07 37327 22680 3 2091.105875 698.0406 Multifunctional protein ADE2 OS=Homo sapiens OX=9606 GN=PAICS PE=1 SV=3 4.68 3583.9 - 996964 - - - 2.7827 - 2.933 0.521 - 491.8 1 2 1 0.0058 20 0 0 0 5.61E+07 5.26E+07 - - - 6.9575 1 221125_WJC_METTL3_EV_vs_WT_F03.22681.22681.3 1.72E-09 17/84 R.VVYGGGAAEISC[160.03]ALAVSQEADK.C "sp|P48643|TCPE_HUMAN,tr|E9PCA1|E9PCA1_HUMAN,tr|B7ZAR1|B7ZAR1_HUMAN,tr|E7ENZ3|E7ENZ3_HUMAN" 4 2194.0576 1.01 37328 22681 3 2194.063391 732.3598 T-complex protein 1 subunit epsilon OS=Homo sapiens OX=9606 GN=CCT5 PE=1 SV=1 4.14 3584 - 4.76E+06 - - - 2.6399 - 3.433 0.625 - 337.4 1 2 0 0.0058 22 0 0 0 9.85E+07 9.79E+07 - - - 8.4308 1 221125_WJC_METTL3_EV_vs_WT_F03.22685.22685.2 2.27E-14 18/54 R.AAAMLPTVGEGYGYGPESELSQASAATR.N sp|Q9BQ04|RBM4B_HUMAN 1 2783.3072 5.06 37332 22685 2 2783.309455 1392.6609 RNA-binding protein 4B OS=Homo sapiens OX=9606 GN=RBM4B PE=1 SV=1 4.25 3584.5 - 754680 - - - 0.8016 - 3.74 0.747 - 440.8 1 2 0 0.0022 28 0 0 0 2.34E+07 4.63E+06 - - - 7.8007 0.9798 221125_WJC_METTL3_EV_vs_WT_F03.22691.22691.2 1.67E-07 15/30 K.IAVYSC[160.03]PFDGMITETK[136.11].G sp|P50990|TCPQ_HUMAN 1 1838.8674 0.13 37336 22691 2 1839.864917 920.441 T-complex protein 1 subunit theta OS=Homo sapiens OX=9606 GN=CCT8 PE=1 SV=4 4.37 3585.1 - 1.98E+06 - - - 542.4584 - 2.749 0.548 - 554.9 1 2 0 0.9975 16 0 0 0 6.65E+06 5.16E+07 - - - 5.2615 1 221125_WJC_METTL3_EV_vs_WT_F03.22699.22699.3 9.05E-06 17/76 K.IGPILDNSTLQSEVK[136.11]PILEK[136.11].L "sp|P30153|2AAA_HUMAN,tr|E9PH38|E9PH38_HUMAN,tr|B3KQV6|B3KQV6_HUMAN" 3 2209.2541 0.95 37342 22699 3 2209.251475 737.4253 Serine\threonine-protein phosphatase 2A 65 kDa regulatory subunit A alpha isoform OS=Homo sapiens OX=9606 GN=PPP2R1A PE=1 SV=4 4.68 3586.2 - 8.65E+06 - - - -1.1656 - 2.747 0.543 - 292.8 1 2 0 -0.0026 20 0 0 0 3.50E+08 3.69E+08 - - - 7.0447 1 221125_WJC_METTL3_EV_vs_WT_F03.22700.22700.3 3.68E-06 19/68 K.GIVDQSQQAYQEAFEISK[136.11].K "sp|P63104|1433Z_HUMAN,tr|H0YB80|H0YB80_HUMAN,tr|E7EX29|E7EX29_HUMAN,tr|B7Z2E6|B7Z2E6_HUMAN,tr|B0AZS6|B0AZS6_HUMAN" 5 2047.9942 1.07 37343 22700 3 2047.992209 683.672 14-3-3 protein zeta\delta OS=Homo sapiens OX=9606 GN=YWHAZ PE=1 SV=1 4.14 3586.3 - 1.98E+06 - - - -0.9722 - 3.124 0.516 - 402.8 1 2 0 -0.002 18 0 0 0 4.93E+07 4.62E+07 - - - 7.1288 1 221125_WJC_METTL3_EV_vs_WT_F03.22701.22701.3 1.44E-08 16/76 K.IGPILDNSTLQSEVKPILEK.L "sp|P30153|2AAA_HUMAN,tr|E9PH38|E9PH38_HUMAN,tr|B3KQV6|B3KQV6_HUMAN" 3 2193.2256 0.95 37344 22701 3 2193.222478 732.0825 Serine\threonine-protein phosphatase 2A 65 kDa regulatory subunit A alpha isoform OS=Homo sapiens OX=9606 GN=PPP2R1A PE=1 SV=4 4.68 3586.3 - 6.71E+06 - - - -1.4463 - 3.164 0.612 - 212.4 1 2 0 -0.0032 20 0 0 0 3.50E+08 3.69E+08 - - - 8.1567 1 221125_WJC_METTL3_EV_vs_WT_F03.22705.22705.2 6.52E-06 15/30 R.QVILQVGVINEAQFSK.A sp|Q08554|DSC1_HUMAN 1 1771.9832 999 37348 22705 2 1771.983076 886.9989 Desmocollin-1 OS=Homo sapiens OX=9606 GN=DSC1 PE=1 SV=2 6 3586.8 - 1.57E+06 - - - -0.0897 - 3.341 0.59 - 674.6 1 2 0 -0.0002 16 0 0 0 3.37E+07 0.00E+00 - - - 6.3644 1 221125_WJC_METTL3_EV_vs_WT_F03.22712.22712.2 1.78E-07 15/34 K.VGDAIPAVEVFEGEPGNK[136.11].V sp|P30044|PRDX5_HUMAN 1 1834.9192 3.37 37353 22712 2 1834.922701 918.4669 "Peroxiredoxin-5, mitochondrial OS=Homo sapiens OX=9606 GN=PRDX5 PE=1 SV=4" 4 3587.6 - 1.72E+06 - - - 1.884 - 3.019 0.575 - 580.3 1 2 0 0.0035 18 0 0 0 8.24E+07 2.45E+07 - - - 6.0034 1 221125_WJC_METTL3_EV_vs_WT_F03.22713.22713.2 8.09E-09 14/26 K.SINDNIAIFTEVQK[136.11].R sp|Q07065|CKAP4_HUMAN 1 1598.8395 1.5 37354 22713 2 1598.836978 800.427 Cytoskeleton-associated protein 4 OS=Homo sapiens OX=9606 GN=CKAP4 PE=1 SV=2 4.37 3587.8 - 1.45E+06 - - - -1.6005 - 2.79 0.57 - 559.8 1 2 0 -0.0026 14 0 0 0 3.32E+07 2.22E+07 - - - 5.825 1 221125_WJC_METTL3_EV_vs_WT_F03.22714.22714.2 3.44E-13 22/42 R.VVYGGGAAEISC[160.03]ALAVSQEADK[136.11].C "sp|P48643|TCPE_HUMAN,tr|E9PCA1|E9PCA1_HUMAN,tr|B7ZAR1|B7ZAR1_HUMAN,tr|E7ENZ3|E7ENZ3_HUMAN" 4 2202.0718 2.07 37355 22714 2 2202.07247 1102.0432 T-complex protein 1 subunit epsilon OS=Homo sapiens OX=9606 GN=CCT5 PE=1 SV=1 4.14 3587.9 - 1.36E+06 - - - 0.3047 - 4.119 0.708 - 1177.9 1 2 0 0.0007 22 0 0 0 2.37E+07 1.14E+07 - - - 7.7504 1 221125_WJC_METTL3_EV_vs_WT_F03.22721.22721.3 1.45E-13 21/76 R.GEYNVYSTFQSHEPEFDYLK[136.11].S "sp|Q66LE6|2ABD_HUMAN,sp|P63151|2ABA_HUMAN,sp|Q00005|2ABB_HUMAN,tr|H0YB06|H0YB06_HUMAN,tr|E5RIY1|E5RIY1_HUMAN" 5 2460.1001 0.4 37360 22721 3 2460.097695 821.0407 Serine\threonine-protein phosphatase 2A 55 kDa regulatory subunit B delta isoform OS=Homo sapiens OX=9606 GN=PPP2R2D PE=1 SV=1 4.4 3588.6 - 5.44E+06 - - - -0.9865 - 3.891 0.679 - 563.9 1 2 0 -0.0024 20 0 0 0 2.66E+07 6.70E+07 - - - 9.4057 0.9999 221125_WJC_METTL3_EV_vs_WT_F03.22728.22728.3 3.86E-05 17/84 K.GVLDLSYGPGPSLRPQNVTSWR.E sp|Q5JSZ5|PRC2B_HUMAN 1 2398.2393 1.01 37365 22728 3 2398.233273 800.4204 Protein PRRC2B OS=Homo sapiens OX=9606 GN=PRRC2B PE=1 SV=2 8.75 3589.5 - 3.24E+06 - - - -2.531 - 3.286 0.488 - 284.7 1 2 0 -0.0061 22 0 0 0 1.11E+08 1.10E+08 - - - 6.7995 0.9999 221125_WJC_METTL3_EV_vs_WT_F03.22734.22734.2 3.41E-06 18-Aug R.DSFPNFLAC[160.03]K.Q sp|P17568|NDUB7_HUMAN 1 1197.5488 2.06 37371 22734 2 1197.548647 599.7817 NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 7 OS=Homo sapiens OX=9606 GN=NDUFB7 PE=1 SV=4 5.83 3590.2 - 1.30E+06 - - - -0.1653 - 1.762 0.531 - 129.6 1 2 0 -0.0002 10 0 0 0 1.05E+08 5.08E+07 - - - 4.544 0.9842 221125_WJC_METTL3_EV_vs_WT_F03.22735.22735.2 9.88E-08 17/38 K.SHLSTAGGLAVPSLPTAGPY.Y sp|Q9H7S9|ZN703_HUMAN 1 1894.9789 - 37372 22735 2 1894.974397 948.4967 Zinc finger protein 703 OS=Homo sapiens OX=9606 GN=ZNF703 PE=1 SV=1 6.46 3590.4 - 1.08E+06 - - - -2.3647 - 2.06 0.612 - 144 1 1 0 -0.0045 20 0 0 0 - - - - - 5.3366 1 221125_WJC_METTL3_EV_vs_WT_F03.22738.22738.3 4.62E-05 19/76 R.GEYNVYSTFQSHEPEFDYLK.S "sp|Q66LE6|2ABD_HUMAN,sp|P63151|2ABA_HUMAN,sp|Q00005|2ABB_HUMAN,tr|H0YB06|H0YB06_HUMAN,tr|E5RIY1|E5RIY1_HUMAN" 5 2452.0859 0.4 37373 22738 3 2452.087612 818.3693 Serine\threonine-protein phosphatase 2A 55 kDa regulatory subunit B delta isoform OS=Homo sapiens OX=9606 GN=PPP2R2D PE=1 SV=1 4.4 3590.7 - 3.64E+06 - - - 0.6892 - 3.47 0.534 - 375.3 1 2 0 0.0017 20 0 0 0 2.66E+07 6.70E+07 - - - 7.5115 1 221125_WJC_METTL3_EV_vs_WT_F03.22739.22739.3 1.14E-06 20/60 K.VR[166.11]PAELEQFESTIGFK[136.11].L "sp|O43491|E41L2_HUMAN,tr|A0A2R8Y5B3|A0A2R8Y5B3_HUMAN,tr|E9PII3|E9PII3_HUMAN,tr|E9PHY5|E9PHY5_HUMAN,tr|E9PK52|E9PK52_HUMAN" 5 1867.9799 0.86 37374 22739 3 1867.974677 623.6672 Band 4.1-like protein 2 OS=Homo sapiens OX=9606 GN=EPB41L2 PE=1 SV=1 4.79 3590.9 - 2.56E+06 - - - -2.7875 - 3.806 0.551 - 724.2 1 2 0 -0.0052 16 0 0 0 1.48E+07 1.73E+07 - - - 8.1111 0.9998 221125_WJC_METTL3_EV_vs_WT_F03.22744.22744.3 2.78E-05 17/60 K.SLLSQEK[136.11]EELQMSLLK[136.11].L sp|Q15643|TRIPB_HUMAN 1 1891.0307 0.1 37377 22744 3 1891.029485 631.3508 Thyroid receptor-interacting protein 11 OS=Homo sapiens OX=9606 GN=TRIP11 PE=1 SV=3 4.78 3591.4 - 1.70E+06 - - - -0.6504 - 2.941 0.437 - 238.2 1 2 1 -0.0012 16 0 0 0 3.00E+07 3.03E+08 - - - 6.1797 0.9991 221125_WJC_METTL3_EV_vs_WT_F03.22745.22745.2 6.78E-06 15/22 K.NIEDVIAQGIGK.L "sp|P05387|RLA2_HUMAN,tr|H0YDD8|H0YDD8_HUMAN" 2 1255.6772 1.26 37378 22745 2 1255.672465 628.8459 60S acidic ribosomal protein P2 OS=Homo sapiens OX=9606 GN=RPLP2 PE=1 SV=1 4.37 3591.5 - 2.48E+06 - - - -3.7836 - 2.34 0.489 - 482 1 2 0 -0.0048 12 0 0 0 8.98E+09 7.14E+09 - - - 4.8882 1 221125_WJC_METTL3_EV_vs_WT_F03.22748.22748.2 2.71E-07 19/30 R.QAQIEVVPSASALIIK.A sp|P30050|RL12_HUMAN 1 1665.9665 1.51 37379 22748 2 1665.964469 833.9905 60S ribosomal protein L12 OS=Homo sapiens OX=9606 GN=RPL12 PE=1 SV=1 6 3591.9 - 6.80E+06 - - - -1.2323 - 3.22 0.625 - 952.6 1 2 0 -0.0021 16 0 0 0 1.35E+09 8.93E+08 - - - 6.5316 1 221125_WJC_METTL3_EV_vs_WT_F03.22751.22751.2 3.14E-08 21/30 R.QAQIEVVPSASALIIK[136.11].A sp|P30050|RL12_HUMAN 1 1673.9807 1.51 37381 22751 2 1673.977933 837.9976 60S ribosomal protein L12 OS=Homo sapiens OX=9606 GN=RPL12 PE=1 SV=1 6 3592.2 - 6.78E+06 - - - -1.6661 - 3.177 0.592 - 1399.4 1 2 0 -0.0028 16 0 0 0 1.35E+09 8.93E+08 - - - 6.2546 1 221125_WJC_METTL3_EV_vs_WT_F03.22753.22753.2 6.49E-07 15/22 K.NIEDVIAQGIGK[136.11].L "sp|P05387|RLA2_HUMAN,tr|H0YDD8|H0YDD8_HUMAN" 2 1263.6914 1.26 37383 22753 2 1263.686613 632.853 60S acidic ribosomal protein P2 OS=Homo sapiens OX=9606 GN=RPLP2 PE=1 SV=1 4.37 3592.3 - 5.24E+06 - - - -3.8008 - 2.458 0.599 - 548.2 1 2 0 -0.0048 12 0 0 0 8.98E+09 7.14E+09 - - - 5.83 1 221125_WJC_METTL3_EV_vs_WT_F03.22756.22756.2 7.32E-11 17/34 K.VGDAIPAVEVFEGEPGNK.V sp|P30044|PRDX5_HUMAN 1 1826.905 2.11 37384 22756 2 1826.910146 914.4598 "Peroxiredoxin-5, mitochondrial OS=Homo sapiens OX=9606 GN=PRDX5 PE=1 SV=4" 4 3592.7 - 2.47E+06 - - - 2.7927 - 2.961 0.593 - 798.2 1 2 0 0.0051 18 0 0 0 4.49E+08 2.13E+08 - - - 6.0881 1 221125_WJC_METTL3_EV_vs_WT_F03.22762.22762.3 2.42E-06 18/60 R.QAQIEVVPSASALIIK[136.11].A sp|P30050|RL12_HUMAN 1 1673.9807 1.44 37387 22762 3 1673.977722 559.0009 60S ribosomal protein L12 OS=Homo sapiens OX=9606 GN=RPL12 PE=1 SV=1 6 3593.5 - 4.98E+06 - - - -1.7921 - 3.274 0.47 - 618.8 1 2 0 -0.003 16 0 0 0 3.47E+08 2.42E+08 - - - 6.8224 0.9995 221125_WJC_METTL3_EV_vs_WT_F03.22767.22767.2 2.46E-06 13/26 K.LNLVDLAGSENIGR.S "sp|P52732|KIF11_HUMAN,tr|A0A7I2YQY4|A0A7I2YQY4_HUMAN,tr|A0A7I2V3A9|A0A7I2V3A9_HUMAN,tr|A0A7I2V3V3|A0A7I2V3V3_HUMAN" 4 1469.7838 6.59 37390 22767 2 1469.778951 735.8992 Kinesin-like protein KIF11 OS=Homo sapiens OX=9606 GN=KIF11 PE=1 SV=2 4.37 3594 - 1.83E+07 - - - -3.3039 - 2.784 0.53 - 409.5 1 2 0 -0.0049 14 0 0 0 4.68E+08 7.09E+07 - - - 5.5235 0.9999 221125_WJC_METTL3_EV_vs_WT_F03.22775.22775.3 1.95E-05 16/44 K.NIEDVIAQGIGK.L "sp|P05387|RLA2_HUMAN,tr|H0YDD8|H0YDD8_HUMAN" 2 1255.6772 1.34 37396 22775 3 1255.673948 419.5663 60S acidic ribosomal protein P2 OS=Homo sapiens OX=9606 GN=RPLP2 PE=1 SV=1 4.37 3594.9 - 2.93E+06 - - - -2.6026 - 2.443 0.436 - 470.5 1 2 0 -0.0033 12 0 0 0 3.74E+08 2.80E+08 - - - 5.876 0.9999 221125_WJC_METTL3_EV_vs_WT_F03.22780.22780.3 1.29E-05 18/60 R.QAQIEVVPSASALIIK.A sp|P30050|RL12_HUMAN 1 1665.9665 1.44 37399 22780 3 1665.962635 556.3295 60S ribosomal protein L12 OS=Homo sapiens OX=9606 GN=RPL12 PE=1 SV=1 6 3595.3 - 1.27E+07 - - - -2.3332 - 3.103 0.468 - 583.5 1 2 0 -0.0039 16 0 0 0 3.47E+08 2.42E+08 - - - 6.6622 0.999 221125_WJC_METTL3_EV_vs_WT_F03.22785.22785.3 0.00958 13/44 K.NIEDVIAQGIGK[136.11].L "sp|P05387|RLA2_HUMAN,tr|H0YDD8|H0YDD8_HUMAN" 2 1263.6914 1.34 37402 22785 3 1263.686346 422.2377 60S acidic ribosomal protein P2 OS=Homo sapiens OX=9606 GN=RPLP2 PE=1 SV=1 4.37 3595.8 - 6.35E+06 - - - -4.0121 - 2.216 0.379 - 315.5 1 2 0 -0.0051 12 0 0 0 3.74E+08 2.80E+08 - - - 4.9696 1 221125_WJC_METTL3_EV_vs_WT_F03.22794.22794.3 7.62E-07 20/60 R.SLQSLEASLHAMESTR[166.11].E sp|Q9UQE7|SMC3_HUMAN 1 1768.8653 2.94 37408 22794 3 1768.863205 590.629 Structural maintenance of chromosomes protein 3 OS=Homo sapiens OX=9606 GN=SMC3 PE=1 SV=2 5.38 3596.8 - 3.26E+06 - - - -1.1946 - 3.525 0.529 - 358.6 1 2 0 -0.0021 16 0 0 0 8.65E+07 2.95E+07 - - - 7.6699 1 221125_WJC_METTL3_EV_vs_WT_F03.22799.22799.3 2.12E-05 18/44 K.K[136.11]PGGFDISLFYR[166.11].D "sp|P12956|XRCC6_HUMAN,tr|B1AHC9|B1AHC9_HUMAN" 2 1416.7521 0.89 37411 22799 3 1416.749038 473.258 X-ray repair cross-complementing protein 6 OS=Homo sapiens OX=9606 GN=XRCC6 PE=1 SV=2 8.59 3597.3 - 2.30E+06 - - - -2.1302 - 2.997 0.503 - 562.4 1 2 0 -0.003 12 0 0 0 8.36E+07 9.39E+07 - - - 7.1895 1 221125_WJC_METTL3_EV_vs_WT_F03.22804.22804.2 6.39E-16 21/34 R.DESSPYAAMLAAQDVAQR[166.11].C "sp|P62263|RS14_HUMAN,tr|A0A2R8Y811|A0A2R8Y811_HUMAN,tr|E5RH77|E5RH77_HUMAN" 3 1931.8923 1.61 37414 22804 2 1931.88634 966.9534 40S ribosomal protein S14 OS=Homo sapiens OX=9606 GN=RPS14 PE=1 SV=3 4.03 3597.8 - 3.44E+06 - - - -3.0649 - 3.817 0.735 - 1541.6 1 2 0 -0.0059 18 0 0 0 2.30E+08 1.43E+08 - - - 7.761 1 221125_WJC_METTL3_EV_vs_WT_F03.22809.22809.2 2.11E-09 17/40 C.LAISTPDAPATQDGVESLLQK[136.11].F "sp|Q86U44|MTA70_HUMAN,tr|B4E349|B4E349_HUMAN,tr|F5H6D8|F5H6D8_HUMAN,tr|H0YFV6|H0YFV6_HUMAN,tr|B4DTN4|B4DTN4_HUMAN" 5 2161.1358 0.03 37417 22809 2 2162.129402 1081.5752 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 4.03 3598.4 - 1.19E+07 - - - 459.7689 - 3.378 0.576 - 606 1 1 0 0.9936 21 0 0 0 1.28E+08 4.10E+09 - - - 5.9761 0.9998 221125_WJC_METTL3_EV_vs_WT_F03.22811.22811.3 2.88E-07 16/60 K.TLDSWRDEFLIQASPR.D "sp|P51149|RAB7A_HUMAN,tr|C9J592|C9J592_HUMAN,tr|A0A6Q8PH84|A0A6Q8PH84_HUMAN,tr|C9IZZ0|C9IZZ0_HUMAN,tr|A0A6Q8PGE6|A0A6Q8PGE6_HUMAN,tr|A0A6Q8PG52|A0A6Q8PG52_HUMAN" 6 1932.9694 1.58 37419 22811 3 1932.964747 645.3304 Ras-related protein Rab-7a OS=Homo sapiens OX=9606 GN=RAB7A PE=1 SV=1 4.56 3598.5 - 8.48E+06 - - - -2.3948 - 2.783 0.535 - 347 1 2 1 -0.0046 16 0 0 0 1.67E+08 1.05E+08 - - - 7.1297 1 221125_WJC_METTL3_EV_vs_WT_F03.22818.22818.2 9.81E-10 14/24 K.FNADEFEDMVAEK[136.11].R "sp|P27635|RL10_HUMAN,tr|F8W7C6|F8W7C6_HUMAN,tr|X1WI28|X1WI28_HUMAN" 3 1551.6643 1.53 37424 22818 2 1551.660294 776.8394 60S ribosomal protein L10 OS=Homo sapiens OX=9606 GN=RPL10 PE=1 SV=4 3.83 3599.3 - 3.70E+06 - - - -2.5656 - 2.945 0.645 - 475.5 1 2 0 -0.004 13 0 0 0 1.17E+08 7.64E+07 - - - 6.5759 1 221125_WJC_METTL3_EV_vs_WT_F03.22819.22819.3 8.42E-10 19/68 R.DESSPYAAMLAAQDVAQR[166.11].C "sp|P62263|RS14_HUMAN,tr|A0A2R8Y811|A0A2R8Y811_HUMAN,tr|E5RH77|E5RH77_HUMAN" 3 1931.8923 1.16 37425 22819 3 1931.886979 644.9714 40S ribosomal protein S14 OS=Homo sapiens OX=9606 GN=RPS14 PE=1 SV=3 4.03 3599.3 - 5.80E+06 - - - -2.7341 - 3.334 0.63 - 514.5 1 2 0 -0.0053 18 0 0 0 1.65E+08 1.42E+08 - - - 8.5609 1 221125_WJC_METTL3_EV_vs_WT_F03.22821.22821.3 2.90E-11 15/68 R.DESSPYAAMLAAQDVAQR.C "sp|P62263|RS14_HUMAN,tr|A0A2R8Y811|A0A2R8Y811_HUMAN,tr|E5RH77|E5RH77_HUMAN" 3 1921.884 1.17 37427 22821 3 1921.880115 641.6353 40S ribosomal protein S14 OS=Homo sapiens OX=9606 GN=RPS14 PE=1 SV=3 4.03 3599.4 - 7.60E+06 - - - -2.0168 - 3.064 0.684 - 377.1 1 2 0 -0.0039 18 0 0 0 1.65E+08 1.41E+08 - - - 8.9531 0.9994 221125_WJC_METTL3_EV_vs_WT_F03.22822.22822.3 1.31E-05 22/60 K.TLDSWR[166.11]DEFLIQASPR[166.11].D "sp|P51149|RAB7A_HUMAN,tr|C9J592|C9J592_HUMAN,tr|A0A6Q8PH84|A0A6Q8PH84_HUMAN,tr|C9IZZ0|C9IZZ0_HUMAN,tr|A0A6Q8PGE6|A0A6Q8PGE6_HUMAN,tr|A0A6Q8PG52|A0A6Q8PG52_HUMAN" 6 1952.9859 1.63 37428 22822 3 1952.976865 652.0026 Ras-related protein Rab-7a OS=Homo sapiens OX=9606 GN=RAB7A PE=1 SV=1 4.56 3599.5 - 3.31E+06 - - - -4.6344 - 3.49 0.568 - 438 1 2 1 -0.0091 16 0 0 0 1.62E+08 9.94E+07 - - - 8.0772 0.9999 221125_WJC_METTL3_EV_vs_WT_F03.22828.22828.3 6.46E-05 22/56 R.DALPELLGLEAGSR[166.11]R[166.11].Q "sp|Q9NSI2|SLX9_HUMAN,tr|C9JJU7|C9JJU7_HUMAN" 2 1615.8797 1.73 37432 22828 3 1615.874944 539.6338 Ribosome biogenesis protein SLX9 homolog OS=Homo sapiens OX=9606 GN=SLX9 PE=1 SV=2 4.68 3600.1 - 3.52E+06 - - - -2.9185 - 3.073 0.458 - 527.6 1 2 0 -0.0047 15 0 0 0 1.82E+08 1.05E+08 - - - 6.5744 1 221125_WJC_METTL3_EV_vs_WT_F03.22830.22830.2 3.95E-11 17/34 R.DESSPYAAMLAAQDVAQR.C "sp|P62263|RS14_HUMAN,tr|A0A2R8Y811|A0A2R8Y811_HUMAN,tr|E5RH77|E5RH77_HUMAN" 3 1921.884 1.61 37434 22830 2 1921.877101 961.9493 40S ribosomal protein S14 OS=Homo sapiens OX=9606 GN=RPS14 PE=1 SV=3 4.03 3600.2 - 8.95E+06 - - - -3.585 - 2.668 0.638 - 586.5 1 2 0 -0.0069 18 0 0 0 2.30E+08 1.43E+08 - - - 6.1637 0.9999 221125_WJC_METTL3_EV_vs_WT_F03.22831.22831.3 0.000759 17/56 R.DALPELLGLEAGSRR.Q "sp|Q9NSI2|SLX9_HUMAN,tr|C9JJU7|C9JJU7_HUMAN" 2 1595.8631 1.74 37435 22831 3 1595.859485 532.9616 Ribosome biogenesis protein SLX9 homolog OS=Homo sapiens OX=9606 GN=SLX9 PE=1 SV=2 4.68 3600.3 - 5.17E+06 - - - -2.2778 - 2.773 0.45 - 279.9 1 2 0 -0.0036 15 0 0 0 1.84E+08 1.06E+08 - - - 6.2174 1 221125_WJC_METTL3_EV_vs_WT_F03.22834.22834.2 1.27E-08 18/34 K.GADFLVTEVENGGSLGSK.K "sp|P14618|KPYM_HUMAN,tr|H3BQ34|H3BQ34_HUMAN,tr|B4DNK4|B4DNK4_HUMAN,tr|A0A804F6T5|A0A804F6T5_HUMAN,tr|H3BTN5|H3BTN5_HUMAN,tr|A0A804F729|A0A804F729_HUMAN" 6 1778.8687 1.77 37436 22834 2 1778.864528 890.4416 Pyruvate kinase PKM OS=Homo sapiens OX=9606 GN=PKM PE=1 SV=4 4.14 3600.7 - 4.04E+06 - - - -2.3223 - 3.745 0.53 - 1144.6 1 2 0 -0.0041 18 0 0 0 1.30E+08 7.37E+07 - - - 6.2006 0.9998 221125_WJC_METTL3_EV_vs_WT_F03.22835.22835.3 4.52E-08 20/60 K.GNIIISTPEKWDILSR.R sp|O75643|U520_HUMAN 1 1841.0047 1.35 37437 22835 3 1841.000099 614.6755 U5 small nuclear ribonucleoprotein 200 kDa helicase OS=Homo sapiens OX=9606 GN=SNRNP200 PE=1 SV=2 6.07 3600.8 - 2.03E+06 - - - -2.4986 - 3.155 0.537 - 367.9 1 2 1 -0.0046 16 0 0 0 3.43E+07 2.55E+07 - - - 7.4739 1 221125_WJC_METTL3_EV_vs_WT_F03.22839.22839.3 1.57E-06 20/60 K.GLDVDSLVIEHIQVNK.A "sp|P18621|RL17_HUMAN,tr|A0A087WWH0|A0A087WWH0_HUMAN,tr|J3QS96|J3QS96_HUMAN,tr|J3QLC8|J3QLC8_HUMAN,tr|J3QQT2|J3QQT2_HUMAN,tr|A0A0A0MRF8|A0A0A0MRF8_HUMAN,tr|J3KRB3|J3KRB3_HUMAN,tr|J3KRX5|J3KRX5_HUMAN,tr|A0A087WXM6|A0A087WXM6_HUMAN,tr|A0A0A6YYL6|A0A0A6YYL6_HUMAN" 10 1777.9574 0.96 37439 22839 3 1777.954364 593.6597 60S ribosomal protein L17 OS=Homo sapiens OX=9606 GN=RPL17 PE=1 SV=3 4.54 3601.3 - 1.15E+07 - - - -1.7155 - 3.429 0.547 - 374.7 1 2 0 -0.0031 16 0 0 0 7.74E+08 8.04E+08 - - - 7.7995 0.9999 221125_WJC_METTL3_EV_vs_WT_F03.22841.22841.3 7.48E-06 15/60 K.GLDVDSLVIEHIQVNK[136.11].A "sp|P18621|RL17_HUMAN,tr|A0A087WWH0|A0A087WWH0_HUMAN,tr|J3QS96|J3QS96_HUMAN,tr|J3QLC8|J3QLC8_HUMAN,tr|J3QQT2|J3QQT2_HUMAN,tr|A0A0A0MRF8|A0A0A0MRF8_HUMAN,tr|J3KRB3|J3KRB3_HUMAN,tr|J3KRX5|J3KRX5_HUMAN,tr|A0A087WXM6|A0A087WXM6_HUMAN,tr|A0A0A6YYL6|A0A0A6YYL6_HUMAN" 10 1785.9716 0.96 37441 22841 3 1785.96542 596.3311 60S ribosomal protein L17 OS=Homo sapiens OX=9606 GN=RPL17 PE=1 SV=3 4.54 3601.5 - 9.47E+06 - - - -3.4681 - 2.514 0.518 - 153.8 1 2 0 -0.0062 16 0 0 0 7.70E+08 8.01E+08 - - - 6.6789 0.9999 221125_WJC_METTL3_EV_vs_WT_F03.22842.22842.3 3.25E-07 24/52 K.SLNNQFASFIDKVR.F sp|P04264|K2C1_HUMAN 1 1637.8526 1934.94 37442 22842 3 1637.850483 546.9581 "Keratin, type II cytoskeletal 1 OS=Homo sapiens OX=9606 GN=KRT1 PE=1 SV=6" 8.46 3601.6 - 3.99E+06 - - - -1.2651 - 3.242 0.6 - 602.3 1 2 1 -0.0021 14 0 0 0 8.83E+08 4.56E+05 - - - 8.3546 1 221125_WJC_METTL3_EV_vs_WT_F03.22843.22843.2 1.31E-09 18/30 R.GIAPIWISGENIPQEK.D "sp|Q16342|PDCD2_HUMAN,tr|F5H4V9|F5H4V9_HUMAN" 2 1750.9254 3.78 37443 22843 2 1750.919589 876.47 Programmed cell death protein 2 OS=Homo sapiens OX=9606 GN=PDCD2 PE=1 SV=2 4.53 3601.7 - 1.92E+06 - - - -3.3108 - 3.364 0.605 - 746.5 1 2 0 -0.0058 16 0 0 0 3.53E+07 9.33E+06 - - - 6.4902 1 221125_WJC_METTL3_EV_vs_WT_F03.22844.22844.3 3.97E-08 21/84 R.LPPEPGLSDSYSFDYPSDMGPR[166.11].R "tr|E9PAU2|E9PAU2_HUMAN,tr|A0A087WZ13|A0A087WZ13_HUMAN" 2 2436.0819 0.95 37444 22844 3 2436.075519 813.0346 Ribonucleoprotein PTB-binding 1 OS=Homo sapiens OX=9606 GN=RAVER1 PE=1 SV=1 3.84 3601.8 - 1.81E+06 - - - -2.6243 - 3.718 0.63 - 314.9 1 2 0 -0.0064 22 0 0 0 4.12E+07 4.33E+07 - - - 8.6755 0.9999 221125_WJC_METTL3_EV_vs_WT_F03.22846.22846.2 6.12E-10 18/34 K.SSGPTSLFAVTVAPPGAR.Q "sp|Q00839|HNRPU_HUMAN,tr|A0A1W2PP35|A0A1W2PP35_HUMAN,tr|A0A1W2PPS1|A0A1W2PPS1_HUMAN,tr|A0A1W2PP22|A0A1W2PP22_HUMAN,tr|A0A1X7SBS1|A0A1X7SBS1_HUMAN" 5 1713.905 1.09 37445 22846 2 1713.902317 857.9598 Heterogeneous nuclear ribonucleoprotein U OS=Homo sapiens OX=9606 GN=HNRNPU PE=1 SV=6 9.47 3602.1 - 4.01E+06 - - - -1.5561 - 2.961 0.533 - 772.6 1 2 0 -0.0027 18 0 0 0 8.72E+09 8.01E+09 - - - 5.6457 0.9997 221125_WJC_METTL3_EV_vs_WT_F03.22851.22851.2 2.42E-05 14/34 K.SSGPTSLFAVTVAPPGAR[166.11].Q "sp|Q00839|HNRPU_HUMAN,tr|A0A1W2PP35|A0A1W2PP35_HUMAN,tr|A0A1W2PPS1|A0A1W2PPS1_HUMAN,tr|A0A1W2PP22|A0A1W2PP22_HUMAN,tr|A0A1X7SBS1|A0A1X7SBS1_HUMAN" 5 1723.9133 1.09 37448 22851 2 1723.915845 862.9639 Heterogeneous nuclear ribonucleoprotein U OS=Homo sapiens OX=9606 GN=HNRNPU PE=1 SV=6 9.47 3602.5 - 1.92E+06 - - - 1.503 - 2.351 0.422 - 540.7 1 2 0 0.0026 18 0 0 0 8.72E+09 8.01E+09 - - - 4.2587 1 221125_WJC_METTL3_EV_vs_WT_F03.22853.22853.3 1.13E-11 28/108 R.HLLPNSGAAATSAAMAAAAATTSSYYGR.D sp|Q9BQ04|RBM4B_HUMAN 1 2681.2868 1.83 37449 22853 3 2681.287699 894.7695 RNA-binding protein 4B OS=Homo sapiens OX=9606 GN=RBM4B PE=1 SV=1 8.6 3602.7 - 1.27E+07 - - - 0.3487 - 5.158 0.667 - 952.5 1 2 0 0.0009 28 0 0 0 1.95E+08 1.07E+08 - - - 9.7504 1 221125_WJC_METTL3_EV_vs_WT_F03.22858.22858.4 7.75E-13 32/162 R.HLLPNSGAAATSAAMAAAAATTSSYYGR.D sp|Q9BQ04|RBM4B_HUMAN 1 2681.2868 0.97 37452 22858 4 2681.287398 671.329 RNA-binding protein 4B OS=Homo sapiens OX=9606 GN=RBM4B PE=1 SV=1 8.6 3603.3 - 1.94E+06 - - - 0.2365 - 5.937 0.572 - 992.1 1 2 0 0.0006 28 0 0 0 2.07E+07 2.13E+07 - - - 4.7575 0.9999 221125_WJC_METTL3_EV_vs_WT_F03.22859.22859.3 5.77E-08 17/76 R.LQPALPPEAQSVPELEEVAR.V sp|Q8WUF5|IASPP_HUMAN 1 2172.1426 10.48 37453 22859 3 2172.142604 725.0548 RelA-associated inhibitor OS=Homo sapiens OX=9606 GN=PPP1R13L PE=1 SV=4 4.09 3603.4 - 2.04E+06 - - - -0.0207 - 3.33 0.354 - 238.2 1 2 0 0 20 0 0 0 4.87E+07 4.64E+06 - - - 5.4052 1 221125_WJC_METTL3_EV_vs_WT_F03.22860.22860.3 1.66E-10 21/56 R.GFAFVEFSHLQDATR.W sp|P98175|RBM10_HUMAN 1 1723.8318 2.79 37454 22860 3 1723.83102 575.6179 RNA-binding protein 10 OS=Homo sapiens OX=9606 GN=RBM10 PE=1 SV=3 5.32 3603.4 - 8.05E+06 - - - -0.4635 - 3.76 0.643 - 634.8 1 2 0 -0.0008 15 0 0 0 2.30E+08 8.26E+07 - - - 9.1645 1 221125_WJC_METTL3_EV_vs_WT_F03.22861.22861.3 1.25E-06 17/56 R.GFAFVEFSHLQDATR[166.11].W sp|P98175|RBM10_HUMAN 1 1733.8401 2.79 37455 22861 3 1733.837189 578.954 RNA-binding protein 10 OS=Homo sapiens OX=9606 GN=RBM10 PE=1 SV=3 5.32 3603.5 - 4.52E+06 - - - -1.6726 - 3.409 0.597 - 275.7 1 2 0 -0.0029 15 0 0 0 2.30E+08 8.26E+07 - - - 8.3953 1 221125_WJC_METTL3_EV_vs_WT_F03.22863.22863.3 1.12E-08 20/64 R.AAVEEGIVLGGGC[160.03]ALLR.C "sp|P10809|CH60_HUMAN,tr|A0A7I2V2X6|A0A7I2V2X6_HUMAN,tr|A0A7I2YQK6|A0A7I2YQK6_HUMAN,tr|A0A7I2V599|A0A7I2V599_HUMAN" 4 1683.8978 1.44 37457 22863 3 1683.89788 562.3065 "60 kDa heat shock protein, mitochondrial OS=Homo sapiens OX=9606 GN=HSPD1 PE=1 SV=2" 4.53 3603.8 - 2.00E+06 - - - 0.0529 - 3.755 0.543 - 474 1 2 0 0.0001 17 0 0 0 6.87E+07 4.78E+07 - - - 7.9364 0.9998 221125_WJC_METTL3_EV_vs_WT_F03.22865.22865.2 0.000706 16-Oct R.DAETWFLSK.T "sp|P08779|K1C16_HUMAN,tr|K7ENW6|K7ENW6_HUMAN" 2 1095.5237 999 37459 22865 2 1095.522881 548.7691 "Keratin, type I cytoskeletal 16 OS=Homo sapiens OX=9606 GN=KRT16 PE=1 SV=4" 4.37 3604 - 2.23E+06 - - - -0.7257 - 1.911 0.443 - 383.8 1 2 0 -0.0008 9 0 0 0 5.98E+07 0.00E+00 - - - 4.1864 1 221125_WJC_METTL3_EV_vs_WT_F03.22868.22868.3 1.31E-07 16/48 R.SSNPMMVLQLPER.C "sp|P78406|RAE1L_HUMAN,tr|E9PQ57|E9PQ57_HUMAN,tr|E9PPG9|E9PPG9_HUMAN" 3 1500.7429 1.86 37462 22868 3 1500.741454 501.2549 mRNA export factor OS=Homo sapiens OX=9606 GN=RAE1 PE=1 SV=1 5.72 3604.4 - 910392 - - - -0.9435 - 2.658 0.523 - 470 1 2 0 -0.0014 13 0 0 0 1.51E+07 8.11E+06 - - - 7.021 1 221125_WJC_METTL3_EV_vs_WT_F03.22869.22869.2 7.93E-11 17/36 R.SSPAAFINPPIGTVTPALK.L "sp|Q9BY77|PDIP3_HUMAN,tr|F6VRR5|F6VRR5_HUMAN,tr|F8WCX5|F8WCX5_HUMAN,tr|Q6R954|Q6R954_HUMAN,tr|Q8WUT1|Q8WUT1_HUMAN,tr|F8WEE2|F8WEE2_HUMAN" 6 1880.0407 1.66 37463 22869 2 1880.036845 941.0277 Polymerase delta-interacting protein 3 OS=Homo sapiens OX=9606 GN=POLDIP3 PE=1 SV=2 8.47 3604.5 - 1.27E+06 - - - -2.0771 - 3.078 0.638 - 438.3 1 2 0 -0.0039 19 0 0 0 6.05E+08 3.63E+08 - - - 6.5161 1 221125_WJC_METTL3_EV_vs_WT_F03.22872.22872.3 3.01E-18 30/108 R.HLLPNSGAAATSAAMAAAAATTSSYYGR[166.11].D sp|Q9BQ04|RBM4B_HUMAN 1 2691.295 1.83 37464 22872 3 2691.291393 898.1056 RNA-binding protein 4B OS=Homo sapiens OX=9606 GN=RBM4B PE=1 SV=1 8.6 3604.9 - 8.39E+06 - - - -1.3529 - 5.476 0.668 - 1192.7 1 2 0 -0.0036 28 0 0 0 1.95E+08 1.07E+08 - - - 9.8985 1 221125_WJC_METTL3_EV_vs_WT_F03.22874.22874.2 1.47E-07 15/30 K.QGGLGPMNIPLVSDPK[136.11].R "sp|Q06830|PRDX1_HUMAN,tr|A0A0A0MSI0|A0A0A0MSI0_HUMAN" 2 1629.864 0.79 37466 22874 2 1629.860796 815.9393 Peroxiredoxin-1 OS=Homo sapiens OX=9606 GN=PRDX1 PE=1 SV=1 5.84 3605 - 5.25E+06 - - - -1.9523 - 2.733 0.636 - 574.7 1 2 0 -0.0032 16 0 0 0 1.21E+08 1.54E+08 - - - 6.2093 1 221125_WJC_METTL3_EV_vs_WT_F03.22875.22875.2 3.36E-06 13/24 R.SSNPMMVLQLPER.C "sp|P78406|RAE1L_HUMAN,tr|E9PQ57|E9PQ57_HUMAN,tr|E9PPG9|E9PPG9_HUMAN" 3 1500.7429 0.75 37467 22875 2 1500.740667 751.3787 mRNA export factor OS=Homo sapiens OX=9606 GN=RAE1 PE=1 SV=1 5.72 3605.1 - 5.17E+06 - - - -1.4679 - 2.349 0.613 - 594.6 1 2 0 -0.0022 13 0 0 0 2.27E+08 3.04E+08 - - - 5.7597 1 221125_WJC_METTL3_EV_vs_WT_F03.22876.22876.3 5.76E-08 18/64 K.TVNELQNLTAAEVVVPR.D sp|Q9NZI8|IF2B1_HUMAN 1 1852.0054 1.67 37468 22876 3 1852.003846 618.3424 Insulin-like growth factor 2 mRNA-binding protein 1 OS=Homo sapiens OX=9606 GN=IGF2BP1 PE=1 SV=2 4.53 3605.1 - 3.06E+06 - - - -0.8537 - 3.056 0.612 - 369.8 1 2 0 -0.0016 17 0 0 0 2.34E+08 1.40E+08 - - - 8.1849 1 221125_WJC_METTL3_EV_vs_WT_F03.22877.22877.3 1.26E-06 Dec-44 K.KPGGFDISLFYR.D "sp|P12956|XRCC6_HUMAN,tr|B1AHC9|B1AHC9_HUMAN" 2 1398.7296 0.89 37469 22877 3 1398.726904 467.2505 X-ray repair cross-complementing protein 6 OS=Homo sapiens OX=9606 GN=XRCC6 PE=1 SV=2 8.59 3605.2 - 2.60E+06 - - - -1.9175 - 2.394 0.504 - 296.5 1 2 0 -0.0027 12 0 0 0 8.37E+07 9.39E+07 - - - 6.5781 0.9997 221125_WJC_METTL3_EV_vs_WT_F03.22879.22879.4 0.0164 19/102 K.GIGIENIHYLNDGLWHMK[136.11].T "sp|Q9ULC4|MCTS1_HUMAN,tr|A0A3B3IRV3|A0A3B3IRV3_HUMAN" 2 2117.0608 0.05 37471 22879 4 2117.057531 530.2725 Malignant T-cell-amplified sequence 1 OS=Homo sapiens OX=9606 GN=MCTS1 PE=1 SV=1 5.99 3605.5 - 1.92E+06 - - - -1.5347 - 2.895 0.344 - 274.1 1 2 0 -0.0032 18 0 0 0 6.60E+06 1.21E+08 - - - 2.5834 1 221125_WJC_METTL3_EV_vs_WT_F03.22883.22883.2 2.93E-05 18/32 R.AAVEEGIVLGGGC[160.03]ALLR[166.11].C "sp|P10809|CH60_HUMAN,tr|A0A7I2V2X6|A0A7I2V2X6_HUMAN,tr|A0A7I2YQK6|A0A7I2YQK6_HUMAN,tr|A0A7I2V599|A0A7I2V599_HUMAN" 4 1693.9061 1.29 37473 22883 2 1693.903401 847.9603 "60 kDa heat shock protein, mitochondrial OS=Homo sapiens OX=9606 GN=HSPD1 PE=1 SV=2" 4.53 3605.9 - 7.62E+06 - - - -1.5703 - 3.741 0.509 - 846.9 1 2 0 -0.0027 17 0 0 0 1.73E+08 1.34E+08 - - - 6.0433 1 221125_WJC_METTL3_EV_vs_WT_F03.22884.22884.2 0.000187 21/36 K.IIAATIENAQPILQIDNAR.L sp|P08779|K1C16_HUMAN 1 2063.1375 999 37474 22884 2 2063.139181 1032.576 "Keratin, type I cytoskeletal 16 OS=Homo sapiens OX=9606 GN=KRT16 PE=1 SV=4" 4.37 3606 - 5.17E+06 - - - 0.8128 - 4.237 0.618 - 1096.7 1 2 0 0.0017 19 0 0 0 7.46E+08 0.00E+00 - - - 7.1548 1 221125_WJC_METTL3_EV_vs_WT_F03.22886.22886.3 1.49E-06 19/64 R.AAVEEGIVLGGGC[160.03]ALLR[166.11].C "sp|P10809|CH60_HUMAN,tr|A0A7I2V2X6|A0A7I2V2X6_HUMAN,tr|A0A7I2YQK6|A0A7I2YQK6_HUMAN,tr|A0A7I2V599|A0A7I2V599_HUMAN" 4 1693.9061 1.43 37476 22886 3 1693.90448 565.6426 "60 kDa heat shock protein, mitochondrial OS=Homo sapiens OX=9606 GN=HSPD1 PE=1 SV=2" 4.53 3606.1 - 3.72E+06 - - - -0.9333 - 3.162 0.446 - 409.1 1 2 0 -0.0016 17 0 0 0 6.87E+07 4.80E+07 - - - 6.4203 1 221125_WJC_METTL3_EV_vs_WT_F03.22887.22887.2 1.95E-07 15/26 K.SLNNQFASFIDKVR.F sp|P04264|K2C1_HUMAN 1 1637.8526 999 37477 22887 2 1637.850709 819.9336 "Keratin, type II cytoskeletal 1 OS=Homo sapiens OX=9606 GN=KRT1 PE=1 SV=6" 8.46 3606.2 - 3.34E+06 - - - -1.1271 - 3.201 0.587 - 959.7 1 2 1 -0.0018 14 0 0 0 6.74E+07 0.00E+00 - - - 6.2957 1 221125_WJC_METTL3_EV_vs_WT_F03.22889.22889.2 6.05E-07 19/32 K.TVNELQNLTAAEVVVPR.D sp|Q9NZI8|IF2B1_HUMAN 1 1852.0054 1.69 37479 22889 2 1852.001548 927.01 Insulin-like growth factor 2 mRNA-binding protein 1 OS=Homo sapiens OX=9606 GN=IGF2BP1 PE=1 SV=2 4.53 3606.4 - 2.10E+06 - - - -2.0945 - 3.739 0.613 - 830.3 1 2 0 -0.0039 17 0 0 0 1.35E+08 7.96E+07 - - - 6.8098 1 221125_WJC_METTL3_EV_vs_WT_F03.22891.22891.2 1.16E-10 21/32 K.TVNELQNLTAAEVVVPR[166.11].D sp|Q9NZI8|IF2B1_HUMAN 1 1862.0137 1.69 37481 22891 2 1862.010328 932.0141 Insulin-like growth factor 2 mRNA-binding protein 1 OS=Homo sapiens OX=9606 GN=IGF2BP1 PE=1 SV=2 4.53 3606.7 - 1.37E+06 - - - -1.8093 - 4.025 0.66 - 1812.4 1 2 0 -0.0034 17 0 0 0 1.35E+08 7.96E+07 - - - 7.3383 0.999 221125_WJC_METTL3_EV_vs_WT_F03.22894.22894.3 1.56E-06 15/60 R.THAAYNLLFFASGGGK.F "sp|Q969V3|NCLN_HUMAN,tr|K7EMW4|K7EMW4_HUMAN,tr|K7ENM2|K7ENM2_HUMAN,tr|A0A0C4DGP7|A0A0C4DGP7_HUMAN" 4 1652.8311 2.97 37484 22894 3 1652.828543 551.951 Nicalin OS=Homo sapiens OX=9606 GN=NCLN PE=1 SV=2 8.29 3607.1 - 833862 - - - -1.5416 - 3.092 0.186 - 277.3 1 2 0 -0.0025 16 0 0 0 1.39E+07 4.69E+06 - - - 3.5094 1 221125_WJC_METTL3_EV_vs_WT_F03.22896.22896.3 1.34E-05 23/72 K.IIAATIENAQPILQIDNAR.L sp|P08779|K1C16_HUMAN 1 2063.1375 12948.29 37485 22896 3 2063.137138 688.7198 "Keratin, type I cytoskeletal 16 OS=Homo sapiens OX=9606 GN=KRT16 PE=1 SV=4" 4.37 3607.3 - 1.13E+08 - - - -0.1774 - 3.493 0.581 - 579.4 1 2 0 -0.0004 19 0 0 0 4.52E+09 3.49E+05 - - - 8.0903 0.9983 221125_WJC_METTL3_EV_vs_WT_F03.22897.22897.2 0.000691 26-Dec K.ETLTFPPEVPISEK.A sp|Q15208|STK38_HUMAN 1 1585.8239 4.33 37486 22897 2 1585.818517 793.9192 Serine\threonine-protein kinase 38 OS=Homo sapiens OX=9606 GN=STK38 PE=1 SV=1 4.25 3607.4 - 2.02E+06 - - - -3.4197 - 1.984 0.394 - 270.8 1 2 0 -0.0054 14 0 0 0 2.97E+07 6.86E+06 - - - 3.6686 0.9998 221125_WJC_METTL3_EV_vs_WT_F03.22900.22900.2 2.18E-05 13/30 K.QGGLGPMNIPLVSDPK.R "sp|Q06830|PRDX1_HUMAN,tr|A0A0A0MSI0|A0A0A0MSI0_HUMAN" 2 1621.8498 0.79 37489 22900 2 1621.848172 811.9322 Peroxiredoxin-1 OS=Homo sapiens OX=9606 GN=PRDX1 PE=1 SV=1 5.84 3607.5 - 4.84E+06 - - - -0.9902 - 2.202 0.472 - 381 1 2 0 -0.0016 16 0 0 0 1.21E+08 1.54E+08 - - - 4.4674 0.9953 221125_WJC_METTL3_EV_vs_WT_F03.22902.22902.3 1.23E-05 16/80 C.LAISTPDAPATQDGVESLLQK[136.11].F "sp|Q86U44|MTA70_HUMAN,tr|B4E349|B4E349_HUMAN,tr|F5H6D8|F5H6D8_HUMAN,tr|H0YFV6|H0YFV6_HUMAN,tr|B4DTN4|B4DTN4_HUMAN" 5 2161.1358 0.04 37491 22902 3 2161.137736 721.3859 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 4.03 3607.7 - 1.67E+06 - - - 0.9055 - 3.075 0.435 - 276.8 1 1 0 0.002 21 0 0 0 9.05E+06 2.20E+08 - - - 6.0824 1 221125_WJC_METTL3_EV_vs_WT_F03.22903.22903.4 0.000399 19/108 K.IIAATIENAQPILQIDNAR.L sp|P08779|K1C16_HUMAN 1 2063.1375 1.7 37492 22903 4 2063.136092 516.7917 "Keratin, type I cytoskeletal 16 OS=Homo sapiens OX=9606 GN=KRT16 PE=1 SV=4" 4.37 3607.8 - 1.12E+06 - - - -0.6844 - 3.182 0.533 - 312.2 1 2 0 -0.0014 19 0 0 0 4.04E+07 2.37E+07 - - - 4.2564 1 221125_WJC_METTL3_EV_vs_WT_F03.22907.22907.3 8.84E-07 20/80 R.APLNVTNTAGTSLPSVDLLQK.L sp|Q9NPI6|DCP1A_HUMAN 1 2138.1583 3.07 37494 22907 3 2138.156491 713.7267 mRNA-decapping enzyme 1A OS=Homo sapiens OX=9606 GN=DCP1A PE=1 SV=3 5.88 3608.3 - 3.01E+06 - - - -0.8456 - 3.603 0.459 - 318.9 1 2 0 -0.0018 21 0 0 0 8.91E+07 2.91E+07 - - - 6.7299 1 221125_WJC_METTL3_EV_vs_WT_F03.22908.22908.3 3.30E-09 15/64 K.TVNELQNLTAAEVVVPR[166.11].D sp|Q9NZI8|IF2B1_HUMAN 1 1862.0137 1.67 37495 22908 3 1862.012571 621.6785 Insulin-like growth factor 2 mRNA-binding protein 1 OS=Homo sapiens OX=9606 GN=IGF2BP1 PE=1 SV=2 4.53 3608.3 - 6.76E+06 - - - -0.6047 - 2.822 0.663 - 370.1 1 2 0 -0.0011 17 0 0 0 2.34E+08 1.40E+08 - - - 8.5524 1 221125_WJC_METTL3_EV_vs_WT_F03.22909.22909.2 6.69E-14 22/30 K.GLDVDSLVIEHIQVNK.A "sp|P18621|RL17_HUMAN,tr|A0A087WWH0|A0A087WWH0_HUMAN,tr|J3QS96|J3QS96_HUMAN,tr|J3QLC8|J3QLC8_HUMAN,tr|J3QQT2|J3QQT2_HUMAN,tr|A0A0A0MRF8|A0A0A0MRF8_HUMAN,tr|J3KRB3|J3KRB3_HUMAN,tr|J3KRX5|J3KRX5_HUMAN,tr|A0A087WXM6|A0A087WXM6_HUMAN,tr|A0A0A6YYL6|A0A0A6YYL6_HUMAN" 10 1777.9574 0.96 37496 22909 2 1777.954067 889.986 60S ribosomal protein L17 OS=Homo sapiens OX=9606 GN=RPL17 PE=1 SV=3 4.54 3608.4 - 2.53E+06 - - - -1.8825 - 4.608 0.635 - 1481.2 1 2 0 -0.0033 16 0 0 0 6.07E+07 6.35E+07 - - - 7.4862 0.9997 221125_WJC_METTL3_EV_vs_WT_F03.22911.22911.3 0.000731 17/68 K.VGDAIPAVEVFEGEPGNK[136.11].V sp|P30044|PRDX5_HUMAN 1 1834.9192 1.96 37498 22911 3 1834.917229 612.647 "Peroxiredoxin-5, mitochondrial OS=Homo sapiens OX=9606 GN=PRDX5 PE=1 SV=4" 4 3608.7 - 1.23E+06 - - - -1.0981 - 1.642 0.405 - 79.8 1 2 0 -0.002 18 0 0 0 7.75E+07 3.96E+07 - - - 4.2897 0.9991 221125_WJC_METTL3_EV_vs_WT_F03.22912.22912.3 0.0198 17/80 R.APLNVTNTAGTSLPSVDLLQK[136.11].L sp|Q9NPI6|DCP1A_HUMAN 1 2146.1725 3.07 37499 22912 3 2146.166217 716.3981 mRNA-decapping enzyme 1A OS=Homo sapiens OX=9606 GN=DCP1A PE=1 SV=3 5.88 3608.8 - 1.56E+06 - - - -2.9271 - 2.575 0.316 - 145.8 1 2 0 -0.0063 21 0 0 0 8.91E+07 2.91E+07 - - - 4.329 0.9979 221125_WJC_METTL3_EV_vs_WT_F03.22915.22915.3 4.43E-08 14/72 R.LASLMNLGMSSSLNQQGAH.S "sp|P43243|MATR3_HUMAN,tr|A0A1B0GX04|A0A1B0GX04_HUMAN,tr|D6RBS2|D6RBS2_HUMAN,tr|A8MXP9|A8MXP9_HUMAN,tr|D6R991|D6R991_HUMAN,tr|D6REK4|D6REK4_HUMAN,tr|D6R9F3|D6R9F3_HUMAN,tr|A0A0R4J2E8|A0A0R4J2E8_HUMAN,tr|D6RCM3|D6RCM3_HUMAN,tr|D6R8Z5|D6R8Z5_HUMAN,tr|D6REM6|D6REM6_HUMAN" 11 1957.935 - 37501 22915 3 1957.931154 653.6523 Matrin-3 OS=Homo sapiens OX=9606 GN=MATR3 PE=1 SV=2 6.74 3609.2 - 6.05E+06 - - - -1.9546 - 2.985 0.609 - 272.2 1 1 0 -0.0038 19 0 0 0 - - - - - 8.0154 1 221125_WJC_METTL3_EV_vs_WT_F03.22917.22917.2 1.98E-12 16/34 R.TIGTGLVTNTLAMTEEEK.N sp|P49411|EFTU_HUMAN 1 1906.9558 0.94 37502 22917 2 1906.946094 954.4852 "Elongation factor Tu, mitochondrial OS=Homo sapiens OX=9606 GN=TUFM PE=1 SV=2" 4.25 3609.4 - 3.18E+06 - - - -5.0683 - 3.297 0.516 - 598.9 1 2 0 -0.0097 18 0 0 0 4.53E+07 4.82E+07 - - - 5.7822 1 221125_WJC_METTL3_EV_vs_WT_F03.22918.22918.3 3.08E-09 18/68 K.TVLQIDDNVTSAVEGINR.M sp|Q15785|TOM34_HUMAN 1 1942.996 1.43 37503 22918 3 1942.994955 648.6726 Mitochondrial import receptor subunit TOM34 OS=Homo sapiens OX=9606 GN=TOMM34 PE=1 SV=2 4.03 3609.4 - 2.79E+06 - - - -0.5296 - 3.107 0.574 - 458.7 1 2 0 -0.001 18 0 0 0 3.40E+07 2.37E+07 - - - 7.7622 1 221125_WJC_METTL3_EV_vs_WT_F03.22920.22920.3 0.000119 19/80 K.LVGTPNPSTPLPNTVPQFIAR.E "sp|Q93062|RBPMS_HUMAN,tr|E5RJ31|E5RJ31_HUMAN,tr|H0YC46|H0YC46_HUMAN,tr|E5RFP4|E5RFP4_HUMAN,tr|H0YBU9|H0YBU9_HUMAN,tr|E5RJD7|E5RJD7_HUMAN,tr|B4E3T4|B4E3T4_HUMAN" 7 2218.211 2.48 37505 22920 3 2218.210175 740.4109 RNA-binding protein with multiple splicing OS=Homo sapiens OX=9606 GN=RBPMS PE=1 SV=1 9.75 3609.7 - 2.01E+06 - - - -0.3733 - 3.249 0.462 - 193 1 2 0 -0.0008 21 0 0 0 2.22E+07 8.93E+06 - - - 6.5156 1 221125_WJC_METTL3_EV_vs_WT_F03.22921.22921.2 1.64E-12 20/34 R.TIGTGLVTNTLAMTEEEK[136.11].N sp|P49411|EFTU_HUMAN 1 1914.97 0.94 37506 22921 2 1914.973201 958.4923 "Elongation factor Tu, mitochondrial OS=Homo sapiens OX=9606 GN=TUFM PE=1 SV=2" 4.25 3609.8 - 1.79E+06 - - - 1.693 - 3.599 0.652 - 1056.2 1 2 0 0.0032 18 0 0 0 4.53E+07 4.82E+07 - - - 7.0042 1 221125_WJC_METTL3_EV_vs_WT_F03.22922.22922.2 2.41E-12 17/40 R.APLNVTNTAGTSLPSVDLLQK.L sp|Q9NPI6|DCP1A_HUMAN 1 2138.1583 7.79 37507 22922 2 2138.159402 1070.0864 mRNA-decapping enzyme 1A OS=Homo sapiens OX=9606 GN=DCP1A PE=1 SV=3 5.88 3609.9 - 1.12E+06 - - - 0.5159 - 3.862 0.693 - 501.4 1 2 0 0.0011 21 0 0 0 1.71E+07 2.20E+06 - - - 7.4811 1 221125_WJC_METTL3_EV_vs_WT_F03.22923.22923.2 2.30E-05 20/34 K.TVLQIDDNVTSAVEGINR[166.11].M sp|Q15785|TOM34_HUMAN 1 1953.0043 1.16 37508 22923 2 1953.000486 977.5094 Mitochondrial import receptor subunit TOM34 OS=Homo sapiens OX=9606 GN=TOMM34 PE=1 SV=2 4.03 3610.1 - 996890 - - - -1.9293 - 3.885 0.623 - 1407.1 1 2 0 -0.0038 18 0 0 0 1.12E+07 9.68E+06 - - - 6.9778 1 221125_WJC_METTL3_EV_vs_WT_F03.22925.22925.3 8.23E-11 19/64 K.FRSETITEEELVGLMNK.F sp|P16152|CBR1_HUMAN 1 1994.9983 1.16 37509 22925 3 1995.000588 666.0067 Carbonyl reductase [NADPH] 1 OS=Homo sapiens OX=9606 GN=CBR1 PE=1 SV=3 4.49 3610.3 - 2.13E+06 - - - 1.1504 - 3.741 0.593 - 574.9 1 2 1 0.0023 17 0 0 0 3.98E+07 3.42E+07 - - - 8.4838 1 221125_WJC_METTL3_EV_vs_WT_F03.22927.22927.3 1.60E-09 21/88 K.TVQVPVYSEQEYQLYLHDDAWTK.A "sp|Q9NPF5|DMAP1_HUMAN,tr|Q5TG39|Q5TG39_HUMAN,tr|Q5TG38|Q5TG38_HUMAN,tr|Q5TG40|Q5TG40_HUMAN" 4 2811.3392 1.31 37510 22927 3 2811.338738 938.1203 DNA methyltransferase 1-associated protein 1 OS=Homo sapiens OX=9606 GN=DMAP1 PE=1 SV=1 4.31 3610.5 - 5.35E+06 - - - -0.1558 - 3.963 0.659 - 297.7 1 2 0 -0.0004 23 0 0 0 3.90E+07 2.97E+07 - - - 9.1174 0.9397 221125_WJC_METTL3_EV_vs_WT_F03.22929.22929.3 4.09E-05 15/68 R.YILPDEPAIIVHPNWAAK.S "sp|Q8IX12|CCAR1_HUMAN,tr|H0YFJ7|H0YFJ7_HUMAN,tr|F5H2E6|F5H2E6_HUMAN,tr|F5H1H2|F5H1H2_HUMAN,tr|A0A0C4DGG8|A0A0C4DGG8_HUMAN" 5 2046.0938 98.43 37512 22929 3 2047.10992 683.0386 Cell division cycle and apoptosis regulator protein 1 OS=Homo sapiens OX=9606 GN=CCAR1 PE=1 SV=2 5.32 3610.6 - 2.88E+06 - - - 496.5911 - 2.878 0.433 - 166.3 1 2 0 1.0161 18 0 0 0 1.85E+07 1.88E+05 - - - 5.7183 1 221125_WJC_METTL3_EV_vs_WT_F03.22931.22931.3 1.99E-06 19/64 R.R[166.11]LPGAIDVIGQTITISR[166.11].V "sp|Q6UN15|FIP1_HUMAN,tr|A0A0B4J203|A0A0B4J203_HUMAN" 2 1829.0638 1.36 37514 22931 3 1829.062858 610.6952 Pre-mRNA 3'-end-processing factor FIP1 OS=Homo sapiens OX=9606 GN=FIP1L1 PE=1 SV=1 9.6 3610.8 - 2.15E+06 - - - -0.4997 - 3.558 0.508 - 451.7 1 2 0 -0.0009 17 0 0 0 3.10E+07 2.29E+07 - - - 7.4098 0.9999 221125_WJC_METTL3_EV_vs_WT_F03.22932.22932.3 7.13E-10 19/64 K.FR[166.11]SETITEEELVGLMNK[136.11].F sp|P16152|CBR1_HUMAN 1 2013.0208 1.16 37515 22932 3 2013.017628 672.0142 Carbonyl reductase [NADPH] 1 OS=Homo sapiens OX=9606 GN=CBR1 PE=1 SV=3 4.49 3610.9 - 1.84E+06 - - - -1.5574 - 3.925 0.444 - 517.3 1 2 1 -0.0031 17 0 0 0 3.98E+07 3.42E+07 - - - 6.9437 1 221125_WJC_METTL3_EV_vs_WT_F03.22934.22934.2 2.73E-06 20/34 K.TVLQIDDNVTSAVEGINR.M sp|Q15785|TOM34_HUMAN 1 1942.996 1.16 37517 22934 2 1942.995702 972.5053 Mitochondrial import receptor subunit TOM34 OS=Homo sapiens OX=9606 GN=TOMM34 PE=1 SV=2 4.03 3611.1 - 1.27E+06 - - - -0.1451 - 3.617 0.594 - 1159.6 1 2 0 -0.0003 18 0 0 0 1.12E+07 9.68E+06 - - - 6.589 1 221125_WJC_METTL3_EV_vs_WT_F03.22936.22936.2 8.42E-11 19/36 R.LASLMNLGMSSSLNQQGAH.S "sp|P43243|MATR3_HUMAN,tr|A0A1B0GX04|A0A1B0GX04_HUMAN,tr|D6RBS2|D6RBS2_HUMAN,tr|A8MXP9|A8MXP9_HUMAN,tr|D6R991|D6R991_HUMAN,tr|D6REK4|D6REK4_HUMAN,tr|D6R9F3|D6R9F3_HUMAN,tr|A0A0R4J2E8|A0A0R4J2E8_HUMAN,tr|D6RCM3|D6RCM3_HUMAN,tr|D6R8Z5|D6R8Z5_HUMAN,tr|D6REM6|D6REM6_HUMAN" 11 1957.935 - 37518 22936 2 1957.93354 979.9748 Matrin-3 OS=Homo sapiens OX=9606 GN=MATR3 PE=1 SV=2 6.74 3611.4 - 1.90E+06 - - - -0.736 - 3.972 0.693 - 1134.7 1 1 0 -0.0014 19 0 0 0 - - - - - 7.55 0.8108 221125_WJC_METTL3_EV_vs_WT_F03.22938.22938.3 0.0138 Aug-60 R.TMQELEIELQSQLSMK.A "sp|P19012|K1C15_HUMAN,tr|C9JTG5|C9JTG5_HUMAN,tr|A8MT21|A8MT21_HUMAN" 3 1906.938 12.83 37519 22938 3 1907.933982 636.6533 "Keratin, type I cytoskeletal 15 OS=Homo sapiens OX=9606 GN=KRT15 PE=1 SV=3" 4.25 3611.6 - 1.16E+07 - - - 522.2933 - 1.679 0.325 - 91.3 1 2 0 0.996 16 0 0 0 1.51E+08 1.18E+07 - - - 3.2172 1 221125_WJC_METTL3_EV_vs_WT_F03.22941.22941.3 1.06E-10 20/84 R.LPPEPGLSDSYSFDYPSDMGPR.R "tr|E9PAU2|E9PAU2_HUMAN,tr|A0A087WZ13|A0A087WZ13_HUMAN" 2 2426.0736 1.15 37522 22941 3 2426.070801 809.6985 Ribonucleoprotein PTB-binding 1 OS=Homo sapiens OX=9606 GN=RAVER1 PE=1 SV=1 3.84 3611.7 - 2.50E+06 - - - -1.171 - 3.663 0.65 - 288.3 1 2 0 -0.0028 22 0 0 0 5.48E+07 4.75E+07 - - - 8.8641 1 221125_WJC_METTL3_EV_vs_WT_F03.22942.22942.3 3.75E-09 16/60 R.HQVLFIADEIQTGLAR[166.11].T sp|P04181|OAT_HUMAN 1 1819.982 1.2 37523 22942 3 1819.97915 607.6679 "Ornithine aminotransferase, mitochondrial OS=Homo sapiens OX=9606 GN=OAT PE=1 SV=1" 5.32 3611.8 - 2.17E+06 - - - -1.5676 - 3.36 0.57 - 491.7 1 2 0 -0.0029 16 0 0 0 1.97E+07 1.64E+07 - - - 8.0038 1 221125_WJC_METTL3_EV_vs_WT_F03.22943.22943.3 1.67E-06 17/60 R.HQVLFIADEIQTGLAR.T sp|P04181|OAT_HUMAN 1 1809.9737 1.2 37524 22943 3 1809.972018 604.3319 "Ornithine aminotransferase, mitochondrial OS=Homo sapiens OX=9606 GN=OAT PE=1 SV=1" 5.32 3611.8 - 2.00E+06 - - - -0.9475 - 2.974 0.545 - 329.7 1 2 0 -0.0017 16 0 0 0 1.97E+07 1.64E+07 - - - 7.4123 1 221125_WJC_METTL3_EV_vs_WT_F03.22944.22944.2 1.49E-10 16/32 R.YLVQDTDEFILPTGANK.T "sp|O14925|TIM23_HUMAN,sp|Q5SRD1|TI23B_HUMAN" 2 1922.9626 3.14 37525 22944 2 1922.965344 962.4886 Mitochondrial import inner membrane translocase subunit Tim23 OS=Homo sapiens OX=9606 GN=TIMM23 PE=1 SV=1 4.03 3612 - 888661 - - - 1.4483 - 3.038 0.641 - 492.7 1 2 0 0.0028 17 0 0 0 1.37E+07 4.34E+06 - - - 6.5065 0.9657 221125_WJC_METTL3_EV_vs_WT_F03.22949.22949.2 0.143 26-Jul K.LFHVSEDPSDLNEK.H sp|P35573|GDE_HUMAN 1 1628.7682 999 37528 22949 2 1628.763027 815.3914 Glycogen debranching enzyme OS=Homo sapiens OX=9606 GN=AGL PE=1 SV=3 4.31 3612.6 - 6.00E+06 - - - -3.1858 - 1.326 0.153 - 83.8 1 2 0 -0.0052 14 0 0 0 1.17E+08 0.00E+00 - - - 0.8775 1 221125_WJC_METTL3_EV_vs_WT_F03.22950.22950.3 3.96E-10 20/64 R.LFVGNLPADITEDEFK[136.11]R[166.11].L sp|P23246|SFPQ_HUMAN 1 1981.0276 0.8 37529 22950 3 1981.025458 661.3498 "Splicing factor, proline- and glutamine-rich OS=Homo sapiens OX=9606 GN=SFPQ PE=1 SV=2" 4.32 3612.7 - 7.05E+06 - - - -1.0621 - 3.38 0.636 - 498.9 1 2 0 -0.0021 17 0 0 0 1.83E+08 2.28E+08 - - - 8.7069 1 221125_WJC_METTL3_EV_vs_WT_F03.22951.22951.3 8.52E-05 16/64 R.LFVGNLPADITEDEFKR.L sp|P23246|SFPQ_HUMAN 1 1963.0051 0.8 37530 22951 3 1963.003102 655.3423 "Splicing factor, proline- and glutamine-rich OS=Homo sapiens OX=9606 GN=SFPQ PE=1 SV=2" 4.32 3612.7 - 4.39E+06 - - - -1.0138 - 2.812 0.552 - 231.4 1 2 0 -0.002 17 0 0 0 1.83E+08 2.28E+08 - - - 7.3056 0.9889 221125_WJC_METTL3_EV_vs_WT_F03.22958.22958.3 0.0278 Oct-60 K.GIYQSLEGAVQAGQLK.V "sp|Q15149|PLEC_HUMAN,tr|E9PMV1|E9PMV1_HUMAN,tr|H0YDN1|H0YDN1_HUMAN" 3 1660.8784 2.87 37537 22958 3 1660.871965 554.6334 Plectin OS=Homo sapiens OX=9606 GN=PLEC PE=1 SV=3 6 3613.5 - 877514 - - - -3.8955 - 2.113 0.228 - 90.8 1 2 0 -0.0065 16 0 0 0 8.14E+06 2.83E+06 - - - 2.9997 0.9959 221125_WJC_METTL3_EV_vs_WT_F03.22959.22959.2 5.61E-10 19/38 K.VGEQAQVVIIDMNDPSNPIR.R "sp|Q00610|CLH1_HUMAN,tr|J3KSQ2|J3KSQ2_HUMAN,tr|J3KS13|J3KS13_HUMAN,tr|J3QL20|J3QL20_HUMAN,tr|A0A087WVQ6|A0A087WVQ6_HUMAN" 5 2194.1052 1.9 37538 22959 2 2194.095926 1098.0599 Clathrin heavy chain 1 OS=Homo sapiens OX=9606 GN=CLTC PE=1 SV=5 4.03 3613.6 - 582490 - - - -4.2345 - 3.666 0.15 - 844.1 1 2 0 -0.0093 20 0 0 0 7.51E+06 3.94E+06 - - - 3.3399 0.9998 221125_WJC_METTL3_EV_vs_WT_F03.22960.22960.4 3.63E-07 19/114 K.FKIEANAGQLYLTGVVVLHK.D sp|O43395|PRPF3_HUMAN 1 2199.2416 4.53 37539 22960 4 2199.241762 550.8177 U4\U6 small nuclear ribonucleoprotein Prp3 OS=Homo sapiens OX=9606 GN=PRPF3 PE=1 SV=2 8.51 3613.7 - 563976 - - - 0.085 - 2.574 0.473 - 179.5 1 2 1 0.0002 20 0 0 0 5.25E+06 1.16E+06 - - - 3.659 0.9999 221125_WJC_METTL3_EV_vs_WT_F03.22965.22965.3 0.000845 15/88 R.YINENLIVNTDELGR[166.11]DC[160.03]LINAAK[136.11].T "sp|P17987|TCPA_HUMAN,tr|F5H136|F5H136_HUMAN,tr|F5H7Y1|F5H7Y1_HUMAN,tr|E7ERF2|E7ERF2_HUMAN" 4 2665.35 0.31 37542 22965 3 2665.348798 889.4573 T-complex protein 1 subunit alpha OS=Homo sapiens OX=9606 GN=TCP1 PE=1 SV=1 4.32 3614.2 - 4.83E+06 - - - -0.4645 - 3.313 0.508 - 139 1 2 1 -0.0012 23 0 0 0 1.01E+07 3.24E+07 - - - 7.0135 0.9999 221125_WJC_METTL3_EV_vs_WT_F03.22966.22966.3 1.48E-05 15/56 K.EAAASGLPLMVIIHK[136.11].S sp|O95881|TXD12_HUMAN 1 1556.884 1.33 37543 22966 3 1556.880975 519.9686 Thioredoxin domain-containing protein 12 OS=Homo sapiens OX=9606 GN=TXNDC12 PE=1 SV=1 6.85 3614.3 - 2.31E+06 - - - -1.9333 - 2.128 0.457 - 176.7 1 2 0 -0.003 15 0 0 0 4.59E+08 3.46E+08 - - - 5.6048 1 221125_WJC_METTL3_EV_vs_WT_F03.22967.22967.3 1.25E-08 19/76 K.VGEQAQVVIIDMNDPSNPIR[166.11].R "sp|Q00610|CLH1_HUMAN,tr|J3KSQ2|J3KSQ2_HUMAN,tr|J3KS13|J3KS13_HUMAN,tr|J3QL20|J3QL20_HUMAN,tr|A0A087WVQ6|A0A087WVQ6_HUMAN" 5 2204.1135 2.06 37544 22967 3 2204.115437 735.7118 Clathrin heavy chain 1 OS=Homo sapiens OX=9606 GN=CLTC PE=1 SV=5 4.03 3614.4 - 2.18E+06 - - - 0.8847 - 3.769 0.594 - 289.2 1 2 0 0.0019 20 0 0 0 4.78E+07 2.32E+07 - - - 8.3808 1 221125_WJC_METTL3_EV_vs_WT_F03.22969.22969.2 4.62E-08 17/26 K.EGPAVVGQFIQDVK[136.11].N "sp|Q86VP6|CAND1_HUMAN,tr|A0A0C4DGH5|A0A0C4DGH5_HUMAN" 2 1493.7969 0.64 37546 22969 2 1493.79511 747.9057 Cullin-associated NEDD8-dissociated protein 1 OS=Homo sapiens OX=9606 GN=CAND1 PE=1 SV=2 4.37 3614.6 - 1.86E+06 - - - -1.2277 - 2.905 0.609 - 1196 1 2 0 -0.0018 14 0 0 0 2.21E+07 3.44E+07 - - - 6.2147 1 221125_WJC_METTL3_EV_vs_WT_F03.22970.22970.2 5.47E-11 23/38 R.SDLGPSYGGWQVLDATPQER.S "sp|Q08188|TGM3_HUMAN,tr|A0A494C0J7|A0A494C0J7_HUMAN" 2 2175.0233 29.99 37547 22970 2 2175.034979 1088.5189 Protein-glutamine gamma-glutamyltransferase E OS=Homo sapiens OX=9606 GN=TGM3 PE=1 SV=4 4.03 3614.7 - 1.31E+06 - - - 5.3871 - 3.948 0.451 - 1387.9 1 2 0 0.0117 20 0 0 0 1.29E+07 4.31E+05 - - - 5.7445 1 221125_WJC_METTL3_EV_vs_WT_F03.22971.22971.3 1.13E-09 19/56 R.MATHTLITGLEEYVR[166.11].E "sp|P46379|BAG6_HUMAN,tr|A0A7I2V508|A0A7I2V508_HUMAN,tr|A0A7P0MQS5|A0A7P0MQS5_HUMAN,tr|A0A0G2JL47|A0A0G2JL47_HUMAN,tr|A0A024RCR6|A0A024RCR6_HUMAN,tr|A0A0G2JK23|A0A0G2JK23_HUMAN" 6 1742.8901 1.31 37548 22971 3 1742.889529 581.9706 Large proline-rich protein BAG6 OS=Homo sapiens OX=9606 GN=BAG6 PE=1 SV=2 5.38 3614.8 - 1.20E+06 - - - -0.3138 - 3.013 0.524 - 596.6 1 2 0 -0.0005 15 0 0 0 2.00E+07 1.53E+07 - - - 7.2599 0.9885 221125_WJC_METTL3_EV_vs_WT_F03.22972.22972.3 0.0424 Sep-40 R.QYK[136.11]IPDWFLNR[166.11].Q "sp|P62269|RS18_HUMAN,tr|J3JS69|J3JS69_HUMAN" 2 1496.7895 0.62 37549 22972 3 1496.78809 499.9371 40S ribosomal protein S18 OS=Homo sapiens OX=9606 GN=RPS18 PE=1 SV=3 8.59 3614.9 - 830770 - - - -0.9447 - 1.76 0.227 - 107.2 1 2 1 -0.0014 11 0 0 0 5.34E+06 8.61E+06 - - - 2.6764 0.9999 221125_WJC_METTL3_EV_vs_WT_F03.22974.22974.3 1.43E-07 15/56 R.ALK[136.11]DFVASIDATYAK[136.11].Q "sp|P25205|MCM3_HUMAN,tr|J3KQ69|J3KQ69_HUMAN,tr|A0A499FHX9|A0A499FHX9_HUMAN" 3 1627.8792 0.54 37551 22974 3 1627.877822 543.6337 DNA replication licensing factor MCM3 OS=Homo sapiens OX=9606 GN=MCM3 PE=1 SV=3 6 3615.2 - 643664 - - - -0.8612 - 2.875 0.472 - 297.7 1 2 1 -0.0014 15 0 0 0 9.45E+06 1.75E+07 - - - 6.5576 0.9907 221125_WJC_METTL3_EV_vs_WT_F03.22975.22975.3 0.0133 Aug-40 R.QYKIPDWFLNR.Q "sp|P62269|RS18_HUMAN,tr|J3JS69|J3JS69_HUMAN" 2 1478.767 0.62 37552 22975 3 1478.764854 493.9296 40S ribosomal protein S18 OS=Homo sapiens OX=9606 GN=RPS18 PE=1 SV=3 8.59 3615.3 - 594118 - - - -1.4742 - 1.71 0.262 - 86.8 1 2 1 -0.0022 11 0 0 0 5.34E+06 8.61E+06 - - - 2.9845 0.9982 221125_WJC_METTL3_EV_vs_WT_F03.22976.22976.3 0.01 Sep-40 R.QSIDALK[136.11]DWFR[166.11].D "sp|O60841|IF2P_HUMAN,tr|A0A087WUT6|A0A087WUT6_HUMAN" 2 1395.7266 0.05 37553 22976 3 1395.726055 466.2495 Eukaryotic translation initiation factor 5B OS=Homo sapiens OX=9606 GN=EIF5B PE=1 SV=4 5.96 3615.4 - 445335 - - - -0.369 - 2.014 0.312 - 130.5 1 2 1 -0.0005 11 0 0 0 4.05E+06 8.34E+07 - - - 4.0073 0.981 221125_WJC_METTL3_EV_vs_WT_F03.22978.22978.3 2.76E-06 20/76 K.VGEQAQVVIIDMNDPSNPIR.R "sp|Q00610|CLH1_HUMAN,tr|J3KSQ2|J3KSQ2_HUMAN,tr|J3KS13|J3KS13_HUMAN,tr|J3QL20|J3QL20_HUMAN,tr|A0A087WVQ6|A0A087WVQ6_HUMAN" 5 2194.1052 2.06 37554 22978 3 2194.096644 732.3757 Clathrin heavy chain 1 OS=Homo sapiens OX=9606 GN=CLTC PE=1 SV=5 4.03 3615.7 - 5.16E+06 - - - -3.9073 - 3.115 0.121 - 389.5 1 2 0 -0.0086 20 0 0 0 4.78E+07 2.32E+07 - - - 2.6432 1 221125_WJC_METTL3_EV_vs_WT_F03.22980.22980.3 4.18E-07 17/72 R.SSPAAFINPPIGTVTPALK.L "sp|Q9BY77|PDIP3_HUMAN,tr|F6VRR5|F6VRR5_HUMAN,tr|F8WCX5|F8WCX5_HUMAN,tr|Q6R954|Q6R954_HUMAN,tr|Q8WUT1|Q8WUT1_HUMAN,tr|F8WEE2|F8WEE2_HUMAN" 6 1880.0407 1.7 37555 22980 3 1880.04142 627.6875 Polymerase delta-interacting protein 3 OS=Homo sapiens OX=9606 GN=POLDIP3 PE=1 SV=2 8.47 3615.9 - 1.28E+07 - - - 0.3564 - 2.778 0.548 - 346.6 1 2 0 0.0007 19 0 0 0 3.51E+08 2.07E+08 - - - 7.1597 1 221125_WJC_METTL3_EV_vs_WT_F03.22981.22981.3 1.43E-06 Dec-72 R.SSPAAFINPPIGTVTPALK[136.11].L "sp|Q9BY77|PDIP3_HUMAN,tr|F6VRR5|F6VRR5_HUMAN,tr|F8WCX5|F8WCX5_HUMAN,tr|Q6R954|Q6R954_HUMAN,tr|Q8WUT1|Q8WUT1_HUMAN,tr|F8WEE2|F8WEE2_HUMAN" 6 1888.0549 1.7 37556 22981 3 1888.054053 630.3589 Polymerase delta-interacting protein 3 OS=Homo sapiens OX=9606 GN=POLDIP3 PE=1 SV=2 8.47 3615.9 - 8.25E+06 - - - -0.4751 - 2.266 0.52 - 118.1 1 2 0 -0.0009 19 0 0 0 3.51E+08 2.07E+08 - - - 6.3469 1 221125_WJC_METTL3_EV_vs_WT_F03.22986.22986.3 7.56E-09 17/52 K.NEVDMQVLHLLGPK.L "sp|P47897|SYQ_HUMAN,tr|B4DDN1|B4DDN1_HUMAN,tr|A0A0U1RRJ7|A0A0U1RRJ7_HUMAN,tr|A0A0U1RQL2|A0A0U1RQL2_HUMAN,tr|A0A0U1RRI9|A0A0U1RRI9_HUMAN,tr|C9J165|C9J165_HUMAN,tr|A0A0U1RQT0|A0A0U1RQT0_HUMAN,tr|A0A1B0GVU9|A0A1B0GVU9_HUMAN,tr|A0A0U1RQE9|A0A0U1RQE9_HUMAN,tr|A0A0U1RQJ6|A0A0U1RQJ6_HUMAN,tr|A0A0U1RR66|A0A0U1RR66_HUMAN" 11 1591.8392 1.16 37561 22986 3 1591.839756 531.6203 Glutamine--tRNA ligase OS=Homo sapiens OX=9606 GN=QARS1 PE=1 SV=1 5.32 3616.2 - 2.57E+06 - - - 0.3411 - 3.193 0.596 - 672.1 1 2 0 0.0005 14 0 0 0 1.85E+07 1.59E+07 - - - 8.27 1 221125_WJC_METTL3_EV_vs_WT_F03.22988.22988.3 1.13E-10 17/52 K.NEVDMQVLHLLGPK[136.11].L "sp|P47897|SYQ_HUMAN,tr|B4DDN1|B4DDN1_HUMAN,tr|A0A0U1RRJ7|A0A0U1RRJ7_HUMAN,tr|A0A0U1RQL2|A0A0U1RQL2_HUMAN,tr|A0A0U1RRI9|A0A0U1RRI9_HUMAN,tr|C9J165|C9J165_HUMAN,tr|A0A0U1RQT0|A0A0U1RQT0_HUMAN,tr|A0A1B0GVU9|A0A1B0GVU9_HUMAN,tr|A0A0U1RQE9|A0A0U1RQE9_HUMAN,tr|A0A0U1RQJ6|A0A0U1RQJ6_HUMAN,tr|A0A0U1RR66|A0A0U1RR66_HUMAN" 11 1599.8534 1.16 37563 22988 3 1599.854694 534.2917 Glutamine--tRNA ligase OS=Homo sapiens OX=9606 GN=QARS1 PE=1 SV=1 5.32 3616.4 - 1.58E+06 - - - 0.8007 - 3.197 0.612 - 626.9 1 2 0 0.0013 14 0 0 0 1.85E+07 1.59E+07 - - - 8.4515 0.9999 221125_WJC_METTL3_EV_vs_WT_F03.22991.22991.3 0.000177 Dec-48 R.DLALHFADDISIK.E sp|Q5VT06|CE350_HUMAN 1 1456.7562 1.24 37566 22991 3 1456.757335 486.5927 Centrosome-associated protein 350 OS=Homo sapiens OX=9606 GN=CEP350 PE=1 SV=1 4.41 3616.7 - 1.36E+06 - - - 0.7826 - 2.391 0.409 - 116.2 1 2 0 0.0011 13 0 0 0 5.97E+06 4.80E+06 - - - 5.4631 0.9995 221125_WJC_METTL3_EV_vs_WT_F03.22993.22993.3 1.05E-05 13/56 R.ALKDFVASIDATYAK.Q "sp|P25205|MCM3_HUMAN,tr|J3KQ69|J3KQ69_HUMAN,tr|A0A499FHX9|A0A499FHX9_HUMAN" 3 1611.8508 0.54 37568 22993 3 1611.855924 538.2909 DNA replication licensing factor MCM3 OS=Homo sapiens OX=9606 GN=MCM3 PE=1 SV=3 6 3617 - 676748 - - - 3.1641 - 2.978 0.485 - 228.1 1 2 1 0.0051 15 0 0 0 9.45E+06 1.75E+07 - - - 6.7933 1 221125_WJC_METTL3_EV_vs_WT_F03.22995.22995.2 2.95E-13 17/32 R.TVNLNLWDTAGQEEYDR[166.11].L sp|P84095|RHOG_HUMAN 1 2032.9366 2.68 37570 22995 2 2032.939013 1017.4756 Rho-related GTP-binding protein RhoG OS=Homo sapiens OX=9606 GN=RHOG PE=1 SV=1 3.92 3617.2 - 565012 - - - 1.2022 - 3.824 0.7 - 1068.8 1 2 0 0.0024 17 0 0 0 1.06E+07 3.94E+06 - - - 7.5081 1 221125_WJC_METTL3_EV_vs_WT_F03.22999.22999.2 1.64E-11 20/36 R.SSPAAFINPPIGTVTPALK.L "sp|Q9BY77|PDIP3_HUMAN,tr|F6VRR5|F6VRR5_HUMAN,tr|F8WCX5|F8WCX5_HUMAN,tr|Q6R954|Q6R954_HUMAN,tr|Q8WUT1|Q8WUT1_HUMAN,tr|F8WEE2|F8WEE2_HUMAN" 6 1880.0407 1.66 37572 22999 2 1880.041204 941.0277 Polymerase delta-interacting protein 3 OS=Homo sapiens OX=9606 GN=POLDIP3 PE=1 SV=2 8.47 3617.8 - 2.36E+07 - - - 0.2415 - 3.279 0.659 - 693.6 1 2 0 0.0005 19 0 0 0 6.05E+08 3.63E+08 - - - 6.8278 0.9999 221125_WJC_METTL3_EV_vs_WT_F03.23001.23001.3 9.98E-09 27/76 K.ISDSVLVDIKDTEPLIQTAK.T "sp|P48643|TCPE_HUMAN,tr|E9PCA1|E9PCA1_HUMAN,tr|B7ZAR1|B7ZAR1_HUMAN,tr|E7ENZ3|E7ENZ3_HUMAN" 4 2184.1889 0.67 37574 23001 3 2184.190439 729.0703 T-complex protein 1 subunit epsilon OS=Homo sapiens OX=9606 GN=CCT5 PE=1 SV=1 4.23 3617.9 - 1.53E+07 - - - 0.6909 - 4.385 0.527 - 898 1 2 1 0.0015 20 0 0 0 5.33E+08 8.01E+08 - - - 8.0012 0.9999 221125_WJC_METTL3_EV_vs_WT_F03.23002.23002.3 4.15E-09 18/72 K.WNTDNTLGTEITVEDQLAR.G "sp|P21796|VDAC1_HUMAN,tr|C9JI87|C9JI87_HUMAN" 2 2175.0444 2.21 37575 23002 3 2175.040635 726.0221 Voltage-dependent anion-selective channel protein 1 OS=Homo sapiens OX=9606 GN=VDAC1 PE=1 SV=2 3.92 3617.9 - 1.19E+07 - - - -1.7269 - 3.287 0.343 - 377.3 1 2 0 -0.0038 19 0 0 0 1.06E+08 4.77E+07 - - - 5.2866 1 221125_WJC_METTL3_EV_vs_WT_F03.23003.23003.3 1.60E-06 13/80 K.AVVPGPAEHPLQYNYTFWYSR.R "sp|O60573|IF4E2_HUMAN,tr|B9A044|B9A044_HUMAN,tr|B8ZZ50|B8ZZ50_HUMAN,tr|C9JEL3|C9JEL3_HUMAN" 4 2494.207 1.61 37576 23003 3 2494.206515 832.4096 Eukaryotic translation initiation factor 4E type 2 OS=Homo sapiens OX=9606 GN=EIF4E2 PE=1 SV=1 6.79 3617.9 - 6.10E+06 - - - -0.1864 - 2.766 0.461 - 174.2 1 2 0 -0.0005 21 0 0 0 5.48E+07 3.39E+07 - - - 6.1187 1 221125_WJC_METTL3_EV_vs_WT_F03.23004.23004.2 5.26E-09 18/32 K.APGEQTVPALNLQNAFR.L sp|Q9Y5B9|SP16H_HUMAN 1 1824.9482 0.98 37577 23004 2 1824.948581 913.4814 FACT complex subunit SPT16 OS=Homo sapiens OX=9606 GN=SUPT16H PE=1 SV=1 6.05 3618 - 2.40E+06 - - - 0.1836 - 3.576 0.628 - 507.3 1 2 0 0.0003 17 0 0 0 3.71E+07 3.81E+07 - - - 6.8121 1 221125_WJC_METTL3_EV_vs_WT_F03.23005.23005.2 9.50E-08 18/32 K.APGEQTVPALNLQNAFR[166.11].L sp|Q9Y5B9|SP16H_HUMAN 1 1834.9565 0.98 37578 23005 2 1834.957422 918.4855 FACT complex subunit SPT16 OS=Homo sapiens OX=9606 GN=SUPT16H PE=1 SV=1 6.05 3618.2 - 2.25E+06 - - - 0.4937 - 3.335 0.599 - 488.8 1 2 0 0.0009 17 0 0 0 3.71E+07 3.81E+07 - - - 6.4262 1 221125_WJC_METTL3_EV_vs_WT_F03.23007.23007.3 0.000155 15/44 R.DTFYIFNHVDIK[136.11].L sp|Q99805|TM9S2_HUMAN 1 1518.7598 1.09 37580 23007 3 1518.759342 507.2606 Transmembrane 9 superfamily member 2 OS=Homo sapiens OX=9606 GN=TM9SF2 PE=1 SV=1 5.21 3618.4 - 1.55E+06 - - - -0.3213 - 2.32 0.505 - 194.6 1 2 0 -0.0005 12 0 0 0 2.60E+07 2.38E+07 - - - 6.5028 1 221125_WJC_METTL3_EV_vs_WT_F03.23009.23009.3 4.61E-07 15/44 R.DTFYIFNHVDIK.L sp|Q99805|TM9S2_HUMAN 1 1510.7456 1.09 37582 23009 3 1510.746594 504.5892 Transmembrane 9 superfamily member 2 OS=Homo sapiens OX=9606 GN=TM9SF2 PE=1 SV=1 5.21 3618.6 - 1.25E+06 - - - 0.6381 - 2.426 0.441 - 246.2 1 2 0 0.001 12 0 0 0 2.62E+07 2.39E+07 - - - 5.913 0.9812 221125_WJC_METTL3_EV_vs_WT_F03.23010.23010.3 0.000636 14/72 K.IIEEEER[166.11]VDILINNAGVMR[166.11].C "sp|Q8NBN7|RDH13_HUMAN,tr|G8JLA1|G8JLA1_HUMAN" 2 2232.1687 0.31 37583 23010 3 2233.17472 745.0635 Retinol dehydrogenase 13 OS=Homo sapiens OX=9606 GN=RDH13 PE=1 SV=2 4.25 3618.8 - 982231 - - - 450.6886 - 2.805 0.38 - 189.6 1 2 1 1.006 19 0 0 0 3.53E+06 1.14E+07 - - - 5.0319 1 221125_WJC_METTL3_EV_vs_WT_F03.23012.23012.2 9.43E-05 14/32 R.LFVGNLPADITEDEFKR.L sp|P23246|SFPQ_HUMAN 1 1963.0051 0.43 37585 23012 2 1963.009688 982.5098 "Splicing factor, proline- and glutamine-rich OS=Homo sapiens OX=9606 GN=SFPQ PE=1 SV=2" 4.32 3619 - 716483 - - - 2.3413 - 2.769 0.569 - 311.7 1 2 0 0.0046 17 0 0 0 2.28E+06 5.33E+06 - - - 5.7462 1 221125_WJC_METTL3_EV_vs_WT_F03.23014.23014.2 3.58E-09 17/34 T.LGNQLDGIHLLDPDVVAR[166.11].F sp|Q86U44|MTA70_HUMAN 1 1954.0511 -1 37587 23014 2 1954.04531 978.0328 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 4.41 3619.3 - 351903 - - - -2.9861 - 3.072 0.585 - 500.9 1 1 0 -0.0058 18 0 0 0 0.00E+00 0.00E+00 - - - 6.1193 1 221125_WJC_METTL3_EV_vs_WT_F03.23018.23018.3 7.83E-08 17/52 K.SNSFFEGVDWEHIR.E sp|Q15208|STK38_HUMAN 1 1721.7798 3.44 37589 23018 3 1721.780643 574.9339 Serine\threonine-protein kinase 38 OS=Homo sapiens OX=9606 GN=STK38 PE=1 SV=1 4.65 3619.7 - 3.08E+07 - - - 0.4989 - 3.137 0.682 - 382.5 1 2 0 0.0009 14 0 0 0 3.88E+08 1.13E+08 - - - 9.1817 1 221125_WJC_METTL3_EV_vs_WT_F03.23019.23019.2 1.59E-11 15/36 R.SSPAAFINPPIGTVTPALK[136.11].L "sp|Q9BY77|PDIP3_HUMAN,tr|F6VRR5|F6VRR5_HUMAN,tr|F8WCX5|F8WCX5_HUMAN,tr|Q6R954|Q6R954_HUMAN,tr|Q8WUT1|Q8WUT1_HUMAN,tr|F8WEE2|F8WEE2_HUMAN" 6 1888.0549 1.66 37590 23019 2 1888.054209 945.0348 Polymerase delta-interacting protein 3 OS=Homo sapiens OX=9606 GN=POLDIP3 PE=1 SV=2 8.47 3619.8 - 1.81E+07 - - - -0.3925 - 2.778 0.641 - 343.7 1 2 0 -0.0007 19 0 0 0 6.05E+08 3.63E+08 - - - 6.2872 1 221125_WJC_METTL3_EV_vs_WT_F03.23020.23020.3 2.45E-09 18/52 K.SNSFFEGVDWEHIR[166.11].E sp|Q15208|STK38_HUMAN 1 1731.7881 3.44 37591 23020 3 1731.788015 578.27 Serine\threonine-protein kinase 38 OS=Homo sapiens OX=9606 GN=STK38 PE=1 SV=1 4.65 3619.8 - 1.04E+07 - - - -0.0225 - 3.313 0.656 - 497 1 2 0 0 14 0 0 0 3.88E+08 1.13E+08 - - - 9.0371 0.9999 221125_WJC_METTL3_EV_vs_WT_F03.23023.23023.3 5.44E-06 15/60 R.SDWEVKEEMDFPQLMK.M "sp|O15371|EIF3D_HUMAN,tr|B0QYA5|B0QYA5_HUMAN" 2 2010.9067 1.23 37594 23023 3 2010.904367 671.3095 Eukaryotic translation initiation factor 3 subunit D OS=Homo sapiens OX=9606 GN=EIF3D PE=1 SV=1 4.18 3620 - 3.07E+06 - - - -1.1602 - 2.542 0.56 - 260.9 1 2 1 -0.0023 16 0 0 0 2.89E+07 2.36E+07 - - - 7.1766 1 221125_WJC_METTL3_EV_vs_WT_F03.23024.23024.2 2.88E-11 18/36 K.WNTDNTLGTEITVEDQLAR[166.11].G "sp|P21796|VDAC1_HUMAN,tr|C9JI87|C9JI87_HUMAN" 2 2185.0527 1.33 37595 23024 2 2185.052438 1093.5336 Voltage-dependent anion-selective channel protein 1 OS=Homo sapiens OX=9606 GN=VDAC1 PE=1 SV=2 3.92 3620.1 - 2.82E+06 - - - -0.1021 - 3.737 0.682 - 775.5 1 2 0 -0.0002 19 0 0 0 3.71E+07 2.78E+07 - - - 7.3192 1 221125_WJC_METTL3_EV_vs_WT_F03.23025.23025.2 1.11E-08 14/26 K.SNSFFEGVDWEHIR.E sp|Q15208|STK38_HUMAN 1 1721.7798 3.54 37596 23025 2 1721.780206 861.8972 Serine\threonine-protein kinase 38 OS=Homo sapiens OX=9606 GN=STK38 PE=1 SV=1 4.65 3620.2 - 2.14E+06 - - - 0.2451 - 2.959 0.679 - 799.5 1 2 0 0.0004 14 0 0 0 3.11E+07 8.80E+06 - - - 6.7783 1 221125_WJC_METTL3_EV_vs_WT_F03.23026.23026.2 4.90E-06 20/28 R.SPAISWVNNLEVDSR[166.11].Y sp|Q9NYU2|UGGG1_HUMAN 1 1695.8456 0.04 37597 23026 2 1695.84236 848.9301 UDP-glucose:glycoprotein glucosyltransferase 1 OS=Homo sapiens OX=9606 GN=UGGT1 PE=1 SV=3 4.37 3620.3 - 2.07E+06 - - - -1.8923 - 3.751 0.589 - 1268.9 1 2 0 -0.0032 15 0 0 0 9.86E+05 2.35E+07 - - - 6.6406 0.9998 221125_WJC_METTL3_EV_vs_WT_F03.23028.23028.4 2.39E-07 20/114 K.ISDSVLVDIKDTEPLIQTAK.T "sp|P48643|TCPE_HUMAN,tr|E9PCA1|E9PCA1_HUMAN,tr|B7ZAR1|B7ZAR1_HUMAN,tr|E7ENZ3|E7ENZ3_HUMAN" 4 2184.1889 0.63 37599 23028 4 2184.186742 547.0545 T-complex protein 1 subunit epsilon OS=Homo sapiens OX=9606 GN=CCT5 PE=1 SV=1 4.23 3620.5 - 1.54E+06 - - - -1.0017 - 2.817 0.482 - 207.7 1 2 1 -0.0022 20 0 0 0 1.84E+07 2.94E+07 - - - 3.767 0.9999 221125_WJC_METTL3_EV_vs_WT_F03.23032.23032.2 2.48E-06 26-Sep K.NWPFLEGC[160.03]AC[160.03]TPER.M "sp|O15392|BIRC5_HUMAN,tr|A0A0B4J1S3|A0A0B4J1S3_HUMAN,tr|K7ELG2|K7ELG2_HUMAN,tr|K7EP76|K7EP76_HUMAN,tr|K7EMW2|K7EMW2_HUMAN,tr|H3BLT4|H3BLT4_HUMAN" 6 1735.7447 15.48 37603 23032 2 1735.742969 868.8796 Baculoviral IAP repeat-containing protein 5 OS=Homo sapiens OX=9606 GN=BIRC5 PE=1 SV=3 4.53 3621 - 779410 - - - -0.9748 - 2.001 0.559 - 202.5 1 2 0 -0.0017 14 0 0 0 9.70E+06 6.27E+05 - - - 4.9099 0.9972 221125_WJC_METTL3_EV_vs_WT_F03.23036.23036.3 9.86E-06 15/76 A.FYVPGVAPINFHQNDPVEIK.A "sp|Q92544|TM9S4_HUMAN,tr|F2Z2L1|F2Z2L1_HUMAN,tr|A0A0C4DFM1|A0A0C4DFM1_HUMAN,tr|F8WCN2|F8WCN2_HUMAN" 4 2283.1688 2.03 37605 23036 3 2283.1683 762.0635 Transmembrane 9 superfamily member 4 OS=Homo sapiens OX=9606 GN=TM9SF4 PE=1 SV=2 5.32 3621.5 - 1.56E+07 - - - -0.2207 - 2.632 0.516 - 134.3 1 1 0 -0.0005 20 0 0 0 1.63E+08 8.03E+07 - - - 6.6405 0.9999 221125_WJC_METTL3_EV_vs_WT_F03.23039.23039.2 4.88E-11 20/32 R.KLFIGGLSFETTDESLR.S "sp|Q32P51|RA1L2_HUMAN,sp|P09651|ROA1_HUMAN,tr|F8W646|F8W646_HUMAN,tr|F8VZ49|F8VZ49_HUMAN,tr|A0A7I2V3R8|A0A7I2V3R8_HUMAN,tr|F8VTQ5|F8VTQ5_HUMAN,tr|A0A7I2YQ85|A0A7I2YQ85_HUMAN,tr|F8W6I7|F8W6I7_HUMAN,tr|A0A7I2V2L6|A0A7I2V2L6_HUMAN,tr|A0A7I2V3W0|A0A7I2V3W0_HUMAN" 10 1911.9942 1.96 37608 23039 2 1911.995661 957.0044 Heterogeneous nuclear ribonucleoprotein A1-like 2 OS=Homo sapiens OX=9606 GN=HNRNPA1L2 PE=2 SV=2 4.68 3621.7 - 2.86E+06 - - - 0.7678 - 3.398 0.403 - 1021.8 1 2 0 0.0015 17 0 0 0 2.32E+07 1.19E+07 - - - 5.0244 1 221125_WJC_METTL3_EV_vs_WT_F03.23040.23040.2 8.94E-13 22/38 K.ISDSVLVDIK[136.11]DTEPLIQTAK[136.11].T "sp|P48643|TCPE_HUMAN,tr|E9PCA1|E9PCA1_HUMAN,tr|B7ZAR1|B7ZAR1_HUMAN,tr|E7ENZ3|E7ENZ3_HUMAN" 4 2200.2173 0.75 37609 23040 2 2200.216378 1101.1159 T-complex protein 1 subunit epsilon OS=Homo sapiens OX=9606 GN=CCT5 PE=1 SV=1 4.23 3621.9 - 1.68E+06 - - - -0.4327 - 4.356 0.694 - 1053.4 1 2 1 -0.001 20 0 0 0 9.63E+06 1.28E+07 - - - 7.7845 1 221125_WJC_METTL3_EV_vs_WT_F03.23041.23041.2 1.66E-11 23/32 R.K[136.11]LFIGGLSFETTDESLR[166.11].S "sp|Q32P51|RA1L2_HUMAN,sp|P09651|ROA1_HUMAN,tr|F8W646|F8W646_HUMAN,tr|F8VZ49|F8VZ49_HUMAN,tr|A0A7I2V3R8|A0A7I2V3R8_HUMAN,tr|F8VTQ5|F8VTQ5_HUMAN,tr|A0A7I2YQ85|A0A7I2YQ85_HUMAN,tr|F8W6I7|F8W6I7_HUMAN,tr|A0A7I2V2L6|A0A7I2V2L6_HUMAN,tr|A0A7I2V3W0|A0A7I2V3W0_HUMAN" 10 1930.0167 1.96 37610 23041 2 1930.014472 966.0156 Heterogeneous nuclear ribonucleoprotein A1-like 2 OS=Homo sapiens OX=9606 GN=HNRNPA1L2 PE=2 SV=2 4.68 3622 - 1.67E+06 - - - -1.1352 - 4.381 0.697 - 1754.4 1 2 0 -0.0022 17 0 0 0 2.32E+07 1.19E+07 - - - 7.8203 1 221125_WJC_METTL3_EV_vs_WT_F03.23042.23042.3 2.00E-05 21/52 R.QTFEAAILTQLHPR.S "sp|Q9NPD3|EXOS4_HUMAN,tr|E9PI41|E9PI41_HUMAN" 2 1623.8733 0.93 37611 23042 3 1623.874074 542.2984 Exosome complex component RRP41 OS=Homo sapiens OX=9606 GN=EXOSC4 PE=1 SV=3 6.75 3622.1 - 1.62E+06 - - - 0.4828 - 3.17 0.55 - 592.6 1 2 0 0.0008 14 0 0 0 1.12E+07 1.20E+07 - - - 7.7378 1 221125_WJC_METTL3_EV_vs_WT_F03.23044.23044.2 2.55E-08 13/26 K.SNSFFEGVDWEHIR[166.11].E sp|Q15208|STK38_HUMAN 1 1731.7881 3.54 37613 23044 2 1731.784309 866.9013 Serine\threonine-protein kinase 38 OS=Homo sapiens OX=9606 GN=STK38 PE=1 SV=1 4.65 3622.4 - 1.31E+06 - - - -2.1625 - 2.878 0.64 - 712.7 1 2 0 -0.0037 14 0 0 0 3.11E+07 8.80E+06 - - - 6.4196 1 221125_WJC_METTL3_EV_vs_WT_F03.23045.23045.3 1.16E-10 20/108 R.VLHALQEAAPEVVQPTTVQSSTIPSLLR[166.11].G sp|Q9NUL7|DDX28_HUMAN 1 2993.6425 0.94 37614 23045 3 2993.638349 998.8881 Probable ATP-dependent RNA helicase DDX28 OS=Homo sapiens OX=9606 GN=DDX28 PE=1 SV=2 5.4 3622.5 - 1.04E+06 - - - -1.3886 - 3.972 0.676 - 297.4 1 2 0 -0.0042 28 0 0 0 8.28E+06 8.81E+06 - - - 9.2488 1 221125_WJC_METTL3_EV_vs_WT_F03.23047.23047.2 5.39E-10 14/28 K.DIPNMFMDSAGSVSK.Q "sp|O94905|ERLN2_HUMAN,tr|E5RHW4|E5RHW4_HUMAN" 2 1597.7116 2.37 37616 23047 2 1597.700755 799.8631 Erlin-2 OS=Homo sapiens OX=9606 GN=ERLIN2 PE=1 SV=1 4.21 3622.7 - 977613 - - - -6.806 - 2.632 0.692 - 507.1 1 2 0 -0.0109 15 0 0 0 1.16E+07 4.91E+06 - - - 6.5279 0.9999 221125_WJC_METTL3_EV_vs_WT_F03.23049.23049.2 0.000276 24-Dec R.TDISLDDPNFWQK.W "sp|Q9P2D1|CHD7_HUMAN,sp|Q9HCK8|CHD8_HUMAN,sp|Q3L8U1|CHD9_HUMAN,sp|Q8TD26|CHD6_HUMAN,tr|H3BTW3|H3BTW3_HUMAN,tr|A0A2R8Y840|A0A2R8Y840_HUMAN,tr|H0YJG4|H0YJG4_HUMAN" 7 1577.7362 1.29 37618 23049 2 1577.734828 789.8754 Chromodomain-helicase-DNA-binding protein 7 OS=Homo sapiens OX=9606 GN=CHD7 PE=1 SV=3 3.93 3623 - 897269 - - - -0.862 - 2.551 0.488 - 482.8 1 2 0 -0.0014 13 0 0 0 1.24E+07 9.60E+06 - - - 5.0485 1 221125_WJC_METTL3_EV_vs_WT_F03.23054.23054.2 1.25E-09 15/28 K.GFGFVTFENSADADR.A "sp|O43251|RFOX2_HUMAN,sp|Q9NWB1|RFOX1_HUMAN,tr|A0A6Q8PGE0|A0A6Q8PGE0_HUMAN,tr|A0A6Q8PH77|A0A6Q8PH77_HUMAN,tr|A0A286YEU2|A0A286YEU2_HUMAN,tr|A0A087X2B1|A0A087X2B1_HUMAN,tr|F8VR27|F8VR27_HUMAN,tr|B7Z1U7|B7Z1U7_HUMAN,tr|B0QYV1|B0QYV1_HUMAN,tr|A0A6Q8PHA3|A0A6Q8PHA3_HUMAN,tr|F8VZY7|F8VZY7_HUMAN,tr|B0QYY4|B0QYY4_HUMAN,tr|J3KNW3|J3KNW3_HUMAN,tr|F8VZG9|F8VZG9_HUMAN,tr|F8VRS4|F8VRS4_HUMAN,tr|A0A6Q8PFM4|A0A6Q8PFM4_HUMAN,tr|S4R469|S4R469_HUMAN,tr|A0A804HKG7|A0A804HKG7_HUMAN,tr|A0A0G2JRD1|A0A0G2JRD1_HUMAN,tr|A0A0G2JRA5|A0A0G2JRA5_HUMAN,tr|A0A804HJM2|A0A804HJM2_HUMAN,tr|I3L1D4|I3L1D4_HUMAN,tr|B0QYY7|B0QYY7_HUMAN,tr|A0A0G2JSB3|A0A0G2JSB3_HUMAN,tr|S4R3K7|S4R3K7_HUMAN" 25 1631.7216 1.28 37621 23054 2 1631.720588 816.8681 RNA binding protein fox-1 homolog 2 OS=Homo sapiens OX=9606 GN=RBFOX2 PE=1 SV=3 4.03 3623.7 - 8.96E+06 - - - -0.6202 - 3.168 0.528 - 723.3 1 2 0 -0.001 15 0 0 0 4.87E+08 3.80E+08 - - - 5.7754 1 221125_WJC_METTL3_EV_vs_WT_F03.23055.23055.3 3.22E-17 16/64 R.C[160.03]EMEQQSQEYQILLDVK.T sp|P08779|K1C16_HUMAN 1 2139.9817 627.76 37622 23055 3 2139.981735 714.3345 "Keratin, type I cytoskeletal 16 OS=Homo sapiens OX=9606 GN=KRT16 PE=1 SV=4" 4 3623.7 - 7.16E+06 - - - 0.0364 - 3.687 0.766 - 342.8 1 2 0 0.0001 17 0 0 0 4.34E+08 6.92E+05 - - - 10.3765 1 221125_WJC_METTL3_EV_vs_WT_F03.23056.23056.3 1.93E-07 19/68 R.GFGFITFTNPEHASVAMR[166.11].A sp|P98179|RBM3_HUMAN 1 1990.9599 1.02 37623 23056 3 1990.957461 664.6606 RNA-binding protein 3 OS=Homo sapiens OX=9606 GN=RBM3 PE=1 SV=1 6.75 3623.7 - 1.63E+07 - - - -1.2185 - 3.541 0.567 - 495.1 1 2 0 -0.0024 18 0 0 0 7.46E+07 7.34E+07 - - - 8.0093 1 221125_WJC_METTL3_EV_vs_WT_F03.23057.23057.3 2.68E-11 25/92 R.VETGVLK[136.11]PGMVVTFAPVNVTTEVK[136.11].S "sp|P68104|EF1A1_HUMAN,sp|Q5VTE0|EF1A3_HUMAN,tr|A0A7I2V659|A0A7I2V659_HUMAN,tr|A0A7I2V3H3|A0A7I2V3H3_HUMAN,tr|A0A7I2V5N4|A0A7I2V5N4_HUMAN,tr|A0A087WVQ9|A0A087WVQ9_HUMAN" 6 2530.4051 0.36 37624 23057 3 2530.403023 844.4757 Elongation factor 1-alpha 1 OS=Homo sapiens OX=9606 GN=EEF1A1 PE=1 SV=1 6.11 3623.8 - 6.20E+06 - - - -0.8398 - 4.577 0.634 - 516.4 1 2 0 -0.0021 24 0 0 0 9.08E+08 2.51E+09 - - - 9.1407 1 221125_WJC_METTL3_EV_vs_WT_F03.23058.23058.3 4.40E-12 18/60 R.SDWEVK[136.11]EEMDFPQLMK[136.11].M "sp|O15371|EIF3D_HUMAN,tr|B0QYA5|B0QYA5_HUMAN" 2 2026.9351 1.21 37625 23058 3 2026.936889 676.6523 Eukaryotic translation initiation factor 3 subunit D OS=Homo sapiens OX=9606 GN=EIF3D PE=1 SV=1 4.18 3623.9 - 3.05E+06 - - - 0.8826 - 2.971 0.646 - 339.9 1 2 1 0.0018 16 0 0 0 2.86E+07 2.36E+07 - - - 8.5357 1 221125_WJC_METTL3_EV_vs_WT_F03.23059.23059.2 4.44E-18 18/32 R.C[160.03]EMEQQSQEYQILLDVK.T sp|P08779|K1C16_HUMAN 1 2139.9817 999 37626 23059 2 2139.980955 1070.9981 "Keratin, type I cytoskeletal 16 OS=Homo sapiens OX=9606 GN=KRT16 PE=1 SV=4" 4 3624 - 3.05E+06 - - - -0.328 - 4.116 0.784 - 729.6 1 2 0 -0.0007 17 0 0 0 2.04E+08 0.00E+00 - - - 8.31 1 221125_WJC_METTL3_EV_vs_WT_F03.23065.23065.3 3.11E-07 16/64 K.APGEQTVPALNLQNAFR[166.11].L sp|Q9Y5B9|SP16H_HUMAN 1 1834.9565 1.69 37632 23065 3 1834.955879 612.6594 FACT complex subunit SPT16 OS=Homo sapiens OX=9606 GN=SUPT16H PE=1 SV=1 6.05 3624.6 - 2.08E+06 - - - -0.3471 - 3.243 0.499 - 396.2 1 2 0 -0.0006 17 0 0 0 3.88E+07 2.30E+07 - - - 7.0754 1 221125_WJC_METTL3_EV_vs_WT_F03.23066.23066.3 1.42E-11 23/68 R.DPEDRIPSPLGYAAIPIK.F sp|Q9Y3A4|RRP7A_HUMAN 1 1951.0415 10.47 37633 23066 3 1951.04132 651.3544 Ribosomal RNA-processing protein 7 homolog A OS=Homo sapiens OX=9606 GN=RRP7A PE=1 SV=2 4.56 3624.7 - 1.74E+06 - - - -0.081 - 4.046 0.623 - 522.9 1 2 1 -0.0002 18 0 0 0 1.15E+08 1.10E+07 - - - 8.9663 1 221125_WJC_METTL3_EV_vs_WT_F03.23067.23067.3 6.75E-11 29/92 R.VETGVLKPGMVVTFAPVNVTTEVK.S "sp|P68104|EF1A1_HUMAN,sp|Q5VTE0|EF1A3_HUMAN,tr|A0A7I2V659|A0A7I2V659_HUMAN,tr|A0A7I2V3H3|A0A7I2V3H3_HUMAN,tr|A0A7I2V5N4|A0A7I2V5N4_HUMAN,tr|A0A087WVQ9|A0A087WVQ9_HUMAN" 6 2514.3767 0.36 37634 23067 3 2514.377112 839.1329 Elongation factor 1-alpha 1 OS=Homo sapiens OX=9606 GN=EEF1A1 PE=1 SV=1 6.11 3624.9 - 1.43E+06 - - - 0.1448 - 5.101 0.625 - 810.1 1 2 0 0.0004 24 0 0 0 9.08E+08 2.51E+09 - - - 9.2926 1 221125_WJC_METTL3_EV_vs_WT_F03.23068.23068.2 2.86E-08 17/30 R.SVIEQGGIQTVDQLIK[136.11].E sp|Q8WUM4|PDC6I_HUMAN 1 1734.9607 1.29 37635 23068 2 1734.955162 868.4876 Programmed cell death 6-interacting protein OS=Homo sapiens OX=9606 GN=PDCD6IP PE=1 SV=1 4.37 3625 - 1.39E+06 - - - -3.2006 - 3.112 0.577 - 892.6 1 2 0 -0.0056 16 0 0 0 1.31E+07 1.02E+07 - - - 6.0921 1 221125_WJC_METTL3_EV_vs_WT_F03.23071.23071.3 4.26E-13 22/68 R.DPEDR[166.11]IPSPLGYAAIPIK[136.11].F sp|Q9Y3A4|RRP7A_HUMAN 1 1969.0639 6.26 37638 23071 3 1969.064962 657.3619 Ribosomal RNA-processing protein 7 homolog A OS=Homo sapiens OX=9606 GN=RRP7A PE=1 SV=2 4.56 3625.4 - 1.15E+06 - - - 0.515 - 4.23 0.646 - 444.5 1 2 1 0.001 18 0 0 0 1.27E+08 2.04E+07 - - - 9.3332 1 221125_WJC_METTL3_EV_vs_WT_F03.23075.23075.2 1.65E-13 19/38 K.ISDSVLVDIKDTEPLIQTAK.T "sp|P48643|TCPE_HUMAN,tr|E9PCA1|E9PCA1_HUMAN,tr|B7ZAR1|B7ZAR1_HUMAN,tr|E7ENZ3|E7ENZ3_HUMAN" 4 2184.1889 0.75 37641 23075 2 2184.189079 1093.1017 T-complex protein 1 subunit epsilon OS=Homo sapiens OX=9606 GN=CCT5 PE=1 SV=1 4.23 3625.9 - 562031 - - - 0.0682 - 3.96 0.642 - 699.6 1 2 1 0.0001 20 0 0 0 9.63E+06 1.28E+07 - - - 7.1663 1 221125_WJC_METTL3_EV_vs_WT_F03.23078.23078.2 8.01E-07 14/24 K.QNFIDPLQNLC[160.03]EK.D "sp|Q99961|SH3G1_HUMAN,tr|M0R0I3|M0R0I3_HUMAN,tr|M0QYE0|M0QYE0_HUMAN" 3 1617.7821 1.39 37644 23078 2 1617.780272 809.8983 Endophilin-A2 OS=Homo sapiens OX=9606 GN=SH3GL1 PE=1 SV=1 4.37 3626.1 - 2.98E+06 - - - -1.125 - 2.698 0.579 - 723.8 1 2 0 -0.0018 13 0 0 0 8.91E+07 6.43E+07 - - - 5.8642 1 221125_WJC_METTL3_EV_vs_WT_F03.23084.23084.2 4.36E-14 14/38 R.VNNSTMLGASGDYADFQYLK.Q sp|P28070|PSB4_HUMAN 1 2193.0048 1.46 37650 23084 2 2193.002015 1097.5097 Proteasome subunit beta type-4 OS=Homo sapiens OX=9606 GN=PSMB4 PE=1 SV=4 4.21 3626.8 - 1.34E+06 - - - -1.2859 - 3.356 0.723 - 434.6 1 2 0 -0.0028 20 0 0 0 1.08E+07 7.40E+06 - - - 7.3569 1 221125_WJC_METTL3_EV_vs_WT_F03.23085.23085.3 1.49E-10 19/88 R.ALLIDEVC[160.03]C[160.03]QNDGPHSALYTMMK.D "sp|Q8TB72|PUM2_HUMAN,tr|A0A0C4DG68|A0A0C4DG68_HUMAN" 2 2665.2009 1.67 37651 23085 3 2665.198534 889.4076 Pumilio homolog 2 OS=Homo sapiens OX=9606 GN=PUM2 PE=1 SV=2 4.54 3626.9 - 1.31E+06 - - - -0.8694 - 3.683 0.654 - 298.1 1 2 0 -0.0023 23 0 0 0 5.47E+07 3.27E+07 - - - 8.8893 1 221125_WJC_METTL3_EV_vs_WT_F03.23086.23086.2 1.38E-05 17/32 K.ALESISSDQQVISEMVK[136.11].E sp|Q8TB72|PUM2_HUMAN 1 1870.9437 1.92 37652 23086 2 1870.940331 936.4791 Pumilio homolog 2 OS=Homo sapiens OX=9606 GN=PUM2 PE=1 SV=2 4.14 3627 - 1.04E+06 - - - -1.8242 - 3.358 0.556 - 882.7 1 2 0 -0.0034 17 0 0 0 1.27E+07 6.62E+06 - - - 6.1247 0.9977 221125_WJC_METTL3_EV_vs_WT_F03.23087.23087.3 0.013 Sep-64 K.ALESISSDQQVISEMVK.E sp|Q8TB72|PUM2_HUMAN 1 1862.9295 10.07 37653 23087 3 1862.933394 621.9838 Pumilio homolog 2 OS=Homo sapiens OX=9606 GN=PUM2 PE=1 SV=2 4.14 3627.1 - 1.03E+06 - - - 2.0666 - 1.794 0.287 - 83.3 1 2 0 0.0039 17 0 0 0 4.91E+07 4.87E+06 - - - 3.2152 0.9992 221125_WJC_METTL3_EV_vs_WT_F03.23091.23091.2 0.000322 13/34 K.AFLASPEYVNLPINGNGK.Q "sp|P09211|GSTP1_HUMAN,tr|A8MX94|A8MX94_HUMAN" 2 1902.984 0.54 37657 23091 2 1902.990696 952.4993 Glutathione S-transferase P OS=Homo sapiens OX=9606 GN=GSTP1 PE=1 SV=2 6.05 3627.6 - 953826 - - - 3.5381 - 2.531 0.481 - 354.6 1 2 0 0.0067 18 0 0 0 8.12E+06 1.50E+07 - - - 4.8746 1 221125_WJC_METTL3_EV_vs_WT_F03.23095.23095.2 1.43E-05 13/28 K.GFGFVC[160.03]FSSPEEATK.A "sp|Q13310|PABP4_HUMAN,sp|Q9H361|PABP3_HUMAN,sp|Q4VXU2|PAP1L_HUMAN,sp|P11940|PABP1_HUMAN,tr|A0A7I2V5W9|A0A7I2V5W9_HUMAN,tr|H0YEU6|H0YEU6_HUMAN,tr|A0A7I2YQE4|A0A7I2YQE4_HUMAN,tr|A0A7I2V649|A0A7I2V649_HUMAN,tr|B1ANR0|B1ANR0_HUMAN,tr|A0A6Q8JFT6|A0A6Q8JFT6_HUMAN,tr|A0A7I2V4L7|A0A7I2V4L7_HUMAN,tr|H0YB86|H0YB86_HUMAN,tr|H0YAR2|H0YAR2_HUMAN,tr|E7ERJ7|E7ERJ7_HUMAN,tr|A0A7I2V598|A0A7I2V598_HUMAN,tr|A0A7I2YQ88|A0A7I2YQ88_HUMAN,tr|A0A7I2V4V6|A0A7I2V4V6_HUMAN,tr|H0Y5F5|H0Y5F5_HUMAN,tr|A0A6I8PS38|A0A6I8PS38_HUMAN,tr|A0A6I8PLA1|A0A6I8PLA1_HUMAN,tr|A0A087WTT1|A0A087WTT1_HUMAN,tr|A0A7I2YQ90|A0A7I2YQ90_HUMAN,tr|A0A7I2V4N4|A0A7I2V4N4_HUMAN,tr|E7EQV3|E7EQV3_HUMAN" 24 1661.7396 1.6 37659 23095 2 1661.737239 831.8771 Polyadenylate-binding protein 4 OS=Homo sapiens OX=9606 GN=PABPC4 PE=1 SV=1 4.53 3628.1 - 5.87E+06 - - - -1.3961 - 2.687 0.618 - 646 1 2 0 -0.0023 15 0 0 0 9.27E+07 5.79E+07 - - - 6.0349 0.9999 221125_WJC_METTL3_EV_vs_WT_F03.23096.23096.4 8.67E-06 17/138 R.VETGVLK[136.11]PGMVVTFAPVNVTTEVK[136.11].S "sp|P68104|EF1A1_HUMAN,sp|Q5VTE0|EF1A3_HUMAN,tr|A0A7I2V659|A0A7I2V659_HUMAN,tr|A0A7I2V3H3|A0A7I2V3H3_HUMAN,tr|A0A7I2V5N4|A0A7I2V5N4_HUMAN,tr|A0A087WVQ9|A0A087WVQ9_HUMAN" 6 2530.4051 0.36 37660 23096 4 2530.40282 633.6086 Elongation factor 1-alpha 1 OS=Homo sapiens OX=9606 GN=EEF1A1 PE=1 SV=1 6.11 3628.2 - 4.52E+06 - - - -0.92 - 2.943 0.462 - 184.4 1 2 0 -0.0023 24 0 0 0 3.63E+07 1.02E+08 - - - 3.5931 1 221125_WJC_METTL3_EV_vs_WT_F03.23097.23097.2 2.06E-06 14/28 K.GFGFVC[160.03]FSSPEEATK[136.11].A "sp|Q13310|PABP4_HUMAN,sp|Q9H361|PABP3_HUMAN,sp|Q4VXU2|PAP1L_HUMAN,sp|P11940|PABP1_HUMAN,tr|A0A7I2V5W9|A0A7I2V5W9_HUMAN,tr|H0YEU6|H0YEU6_HUMAN,tr|A0A7I2YQE4|A0A7I2YQE4_HUMAN,tr|A0A7I2V649|A0A7I2V649_HUMAN,tr|B1ANR0|B1ANR0_HUMAN,tr|A0A6Q8JFT6|A0A6Q8JFT6_HUMAN,tr|A0A7I2V4L7|A0A7I2V4L7_HUMAN,tr|H0YB86|H0YB86_HUMAN,tr|H0YAR2|H0YAR2_HUMAN,tr|E7ERJ7|E7ERJ7_HUMAN,tr|A0A7I2V598|A0A7I2V598_HUMAN,tr|A0A7I2YQ88|A0A7I2YQ88_HUMAN,tr|A0A7I2V4V6|A0A7I2V4V6_HUMAN,tr|H0Y5F5|H0Y5F5_HUMAN,tr|A0A6I8PS38|A0A6I8PS38_HUMAN,tr|A0A6I8PLA1|A0A6I8PLA1_HUMAN,tr|A0A087WTT1|A0A087WTT1_HUMAN,tr|A0A7I2YQ90|A0A7I2YQ90_HUMAN,tr|A0A7I2V4N4|A0A7I2V4N4_HUMAN,tr|E7EQV3|E7EQV3_HUMAN" 24 1669.7538 1.6 37661 23097 2 1669.75214 835.8842 Polyadenylate-binding protein 4 OS=Homo sapiens OX=9606 GN=PABPC4 PE=1 SV=1 4.53 3628.3 - 4.34E+06 - - - -0.9696 - 2.884 0.611 - 668.5 1 2 0 -0.0016 15 0 0 0 9.27E+07 5.79E+07 - - - 6.1574 0.9999 221125_WJC_METTL3_EV_vs_WT_F03.23098.23098.2 0.000252 13/24 K.QNFIDPLQNLC[160.03]EK[136.11].D "sp|Q99961|SH3G1_HUMAN,tr|M0R0I3|M0R0I3_HUMAN,tr|M0QYE0|M0QYE0_HUMAN" 3 1625.7963 1.85 37662 23098 2 1625.795431 813.9054 Endophilin-A2 OS=Homo sapiens OX=9606 GN=SH3GL1 PE=1 SV=1 4.37 3628.3 - 3.44E+06 - - - -0.5296 - 2.423 0.488 - 458.8 1 2 0 -0.0009 13 0 0 0 8.46E+07 4.57E+07 - - - 4.9165 1 221125_WJC_METTL3_EV_vs_WT_F03.23099.23099.2 2.44E-08 22-Oct K.DMTSEQLDDILK.Y sp|P05023|AT1A1_HUMAN 1 1406.6599 1.53 37663 23099 2 1406.656687 704.3372 Sodium\potassium-transporting ATPase subunit alpha-1 OS=Homo sapiens OX=9606 GN=ATP1A1 PE=1 SV=1 3.84 3628.4 - 3.35E+06 - - - -2.292 - 2.401 0.678 - 320 1 2 0 -0.0032 12 0 0 0 3.01E+07 1.97E+07 - - - 6.3523 1 221125_WJC_METTL3_EV_vs_WT_F03.23102.23102.3 1.10E-12 30/92 R.SPLLNQPVPELSHASLIANQSPFR.A sp|Q9NPI6|DCP1A_HUMAN 1 2614.3867 3.49 37666 23102 3 2614.382699 872.4695 mRNA-decapping enzyme 1A OS=Homo sapiens OX=9606 GN=DCP1A PE=1 SV=3 6.47 3628.7 - 1.78E+06 - - - -1.5441 - 5.015 0.677 - 1171 1 2 0 -0.004 24 0 0 0 4.01E+07 1.15E+07 - - - 9.8318 0.9997 221125_WJC_METTL3_EV_vs_WT_F03.23104.23104.2 3.23E-10 16/32 K.DGDSVMVLPTIPEEEAK[136.11].K sp|P30041|PRDX6_HUMAN 1 1836.8906 1.17 37668 23104 2 1836.888036 919.4526 Peroxiredoxin-6 OS=Homo sapiens OX=9606 GN=PRDX6 PE=1 SV=3 3.83 3629 - 1.11E+06 - - - -1.4209 - 3.017 0.299 - 582.1 1 2 0 -0.0026 17 0 0 0 3.45E+07 2.94E+07 - - - 3.9635 1 221125_WJC_METTL3_EV_vs_WT_F03.23105.23105.2 1.69E-09 14/30 K.VQSGSESVIQEYVDLR[166.11].T "sp|Q15149|PLEC_HUMAN,tr|H0YDN1|H0YDN1_HUMAN" 2 1817.9035 0.86 37669 23105 2 1817.906245 909.959 Plectin OS=Homo sapiens OX=9606 GN=PLEC PE=1 SV=3 4.14 3629.1 - 1.03E+06 - - - 1.5221 - 3.043 0.616 - 569.2 1 2 0 0.0028 16 0 0 0 7.10E+06 8.28E+06 - - - 6.3259 0.9714 221125_WJC_METTL3_EV_vs_WT_F03.23106.23106.3 0.457 Aug-60 R.MQDTSVSFGYQLDLPK.A "sp|O96008|TOM40_HUMAN,tr|K7EKG4|K7EKG4_HUMAN" 2 1827.8713 -1 37670 23106 3 1827.872026 610.2977 Mitochondrial import receptor subunit TOM40 homolog OS=Homo sapiens OX=9606 GN=TOMM40 PE=1 SV=1 4.21 3629.2 - 433857 - - - 0.3966 - 1.466 0.149 - 55 1 2 0 0.0007 16 0 0 0 0.00E+00 0.00E+00 - - - 1.1825 1 221125_WJC_METTL3_EV_vs_WT_F03.23109.23109.3 3.81E-09 22/68 R.GFGFITFTNPEHASVAMR.A sp|P98179|RBM3_HUMAN 1 1980.9516 1.03 37671 23109 3 1980.950404 661.3245 RNA-binding protein 3 OS=Homo sapiens OX=9606 GN=RBM3 PE=1 SV=1 6.75 3629.6 - 4.29E+06 - - - -0.6123 - 3.793 0.651 - 686.9 1 2 0 -0.0012 18 0 0 0 7.41E+07 7.23E+07 - - - 9.1174 0.9993 221125_WJC_METTL3_EV_vs_WT_F03.23110.23110.3 0.000926 13/60 K.LTTLPSDFC[160.03]GLTHLVK.L sp|Q96AG4|LRC59_HUMAN 1 1800.9444 1.2 37672 23110 3 1800.948158 601.3221 Leucine-rich repeat-containing protein 59 OS=Homo sapiens OX=9606 GN=LRRC59 PE=1 SV=1 6.73 3629.7 - 1.80E+06 - - - 2.0828 - 2.184 0.326 - 185.5 1 2 0 0.0038 16 0 0 0 1.51E+08 1.25E+08 - - - 4.1779 0.998 221125_WJC_METTL3_EV_vs_WT_F03.23116.23116.2 2.90E-10 14/32 K.DGDSVMVLPTIPEEEAK.K sp|P30041|PRDX6_HUMAN 1 1828.8764 1.17 37678 23116 2 1828.869744 915.4455 Peroxiredoxin-6 OS=Homo sapiens OX=9606 GN=PRDX6 PE=1 SV=3 3.83 3630.3 - 1.45E+06 - - - -3.6645 - 2.92 0.273 - 371.2 1 2 0 -0.0067 17 0 0 0 3.45E+07 2.94E+07 - - - 3.6898 0.9999 221125_WJC_METTL3_EV_vs_WT_F03.23117.23117.4 5.78E-06 17/108 K.LDALSNFHFIPKPPVPEIK.V sp|O00566|MPP10_HUMAN 1 2161.1936 2.45 37679 23117 4 2161.189495 541.3057 U3 small nucleolar ribonucleoprotein protein MPP10 OS=Homo sapiens OX=9606 GN=MPHOSPH10 PE=1 SV=2 6.75 3630.4 - 1.43E+06 - - - -1.8818 - 3.137 0.455 - 188.5 1 2 0 -0.0041 19 0 0 0 4.65E+07 1.90E+07 - - - 3.5719 0.8202 221125_WJC_METTL3_EV_vs_WT_F03.23118.23118.3 0.0706 Nov-96 P.PGPPGPTGVPGSPGHIGPPGPTGPK.G "sp|Q96A84|EMID1_HUMAN,tr|B0QYK5|B0QYK5_HUMAN,tr|H0Y6W4|H0Y6W4_HUMAN" 3 2211.1437 40.53 37680 23118 3 2211.147152 738.0552 EMI domain-containing protein 1 OS=Homo sapiens OX=9606 GN=EMID1 PE=2 SV=1 9.18 3630.5 - 1.38E+06 - - - 1.5829 - 1.892 0.276 - 73.3 1 1 0 0.0035 25 0 0 0 2.93E+07 7.22E+05 - - - 3.0831 1 221125_WJC_METTL3_EV_vs_WT_F03.23119.23119.2 1.86E-08 15/30 K.VQSGSESVIQEYVDLR.T "sp|Q15149|PLEC_HUMAN,tr|H0YDN1|H0YDN1_HUMAN" 2 1807.8952 0.86 37681 23119 2 1807.896987 904.9549 Plectin OS=Homo sapiens OX=9606 GN=PLEC PE=1 SV=3 4.14 3630.7 - 1.01E+06 - - - 0.984 - 3.172 0.649 - 573.6 1 2 0 0.0018 16 0 0 0 7.10E+06 8.28E+06 - - - 6.672 1 221125_WJC_METTL3_EV_vs_WT_F03.23121.23121.2 1.04E-08 14/30 K.SGC[160.03]IVNNLAEFTVDPK.D "sp|O75369|FLNB_HUMAN,tr|E7EN95|E7EN95_HUMAN,tr|A0A804HK76|A0A804HK76_HUMAN,tr|A0A804HL72|A0A804HL72_HUMAN" 4 1762.856 1 37683 23121 2 1762.861464 882.4353 Filamin-B OS=Homo sapiens OX=9606 GN=FLNB PE=1 SV=2 4.37 3630.9 - 0 - - - 3.1075 - 2.748 0.663 - 360.1 1 2 0 0.0055 16 0 0 0 5.36E+06 5.35E+06 - - - 6.4215 0.9993 221125_WJC_METTL3_EV_vs_WT_F03.23125.23125.2 0.0364 30-Dec K.AAPQPLNLVSSVTLSK.S "sp|Q9H334|FOXP1_HUMAN,tr|A0A3B3ISQ6|A0A3B3ISQ6_HUMAN,tr|A0A3B3IRW5|A0A3B3IRW5_HUMAN,tr|G5E965|G5E965_HUMAN,tr|A0A3B3IRS5|A0A3B3IRS5_HUMAN,tr|A0A3B3IST0|A0A3B3IST0_HUMAN,tr|A0A3B3IT14|A0A3B3IT14_HUMAN,tr|C9J0F0|C9J0F0_HUMAN,tr|A0A3B3IUB6|A0A3B3IUB6_HUMAN,tr|H0Y882|H0Y882_HUMAN,tr|A0A3B3IT66|A0A3B3IT66_HUMAN,tr|A0A3B3IS87|A0A3B3IS87_HUMAN,tr|A0A0B4J2F3|A0A0B4J2F3_HUMAN,tr|A0A3B3IST6|A0A3B3IST6_HUMAN" 14 1623.9196 3.78 37685 23125 2 1623.918529 812.9671 Forkhead box protein P1 OS=Homo sapiens OX=9606 GN=FOXP1 PE=1 SV=1 8.8 3631.4 - 3.91E+06 - - - -0.6423 - 1.887 0.3 - 184 1 2 0 -0.001 16 0 0 0 8.63E+07 2.28E+07 - - - 2.8176 1 221125_WJC_METTL3_EV_vs_WT_F03.23127.23127.3 2.36E-07 18/80 K.DLLVTGAYEISDQSGGAGGLR.S "sp|P49755|TMEDA_HUMAN,tr|G3V2K7|G3V2K7_HUMAN" 2 2078.028 1.14 37687 23127 3 2078.028642 693.6833 Transmembrane emp24 domain-containing protein 10 OS=Homo sapiens OX=9606 GN=TMED10 PE=1 SV=2 4.03 3631.5 - 2.30E+06 - - - 0.3027 - 3.122 0.578 - 344.7 1 2 0 0.0006 21 0 0 0 6.31E+07 5.55E+07 - - - 7.7134 1 221125_WJC_METTL3_EV_vs_WT_F03.23128.23128.3 1.29E-09 17/60 K.HASPILPITEFSDIPR.R "sp|P42167|LAP2B_HUMAN,tr|G5E972|G5E972_HUMAN,tr|H0YJH7|H0YJH7_HUMAN" 3 1791.9519 0.78 37688 23128 3 1791.950112 598.3246 "Lamina-associated polypeptide 2, isoforms beta\gamma OS=Homo sapiens OX=9606 GN=TMPO PE=1 SV=2" 5.32 3631.6 - 2.18E+06 - - - -1.0173 - 3.694 0.6 - 512.9 1 2 0 -0.0018 16 0 0 0 1.29E+08 1.67E+08 - - - 8.5817 1 221125_WJC_METTL3_EV_vs_WT_F03.23129.23129.3 0.000209 20/80 R.GPGNPVPGPLAPLPDYMSEEK[136.11].L "sp|Q6P2Q9|PRP8_HUMAN,tr|I3L0J9|I3L0J9_HUMAN" 2 2172.0653 0.69 37689 23129 3 2172.063795 725.029 Pre-mRNA-processing-splicing factor 8 OS=Homo sapiens OX=9606 GN=PRPF8 PE=1 SV=2 4.14 3631.7 - 1.45E+06 - - - -0.6726 - 3.139 0.483 - 287.3 1 2 0 -0.0015 21 0 0 0 1.72E+07 2.50E+07 - - - 6.667 0.9999 221125_WJC_METTL3_EV_vs_WT_F03.23133.23133.4 3.52E-05 15/108 K.LDALSNFHFIPK[136.11]PPVPEIK[136.11].V sp|O00566|MPP10_HUMAN 1 2177.222 2.45 37693 23133 4 2177.218611 545.3128 U3 small nucleolar ribonucleoprotein protein MPP10 OS=Homo sapiens OX=9606 GN=MPHOSPH10 PE=1 SV=2 6.75 3632.2 - 1.12E+06 - - - -1.5391 - 2.932 0.461 - 167.4 1 2 0 -0.0034 19 0 0 0 4.67E+07 1.90E+07 - - - 3.6015 1 221125_WJC_METTL3_EV_vs_WT_F03.23136.23136.2 5.56E-14 21/40 K.DLLVTGAYEISDQSGGAGGLR.S "sp|P49755|TMEDA_HUMAN,tr|G3V2K7|G3V2K7_HUMAN" 2 2078.028 2.16 37696 23136 2 2078.026899 1040.0213 Transmembrane emp24 domain-containing protein 10 OS=Homo sapiens OX=9606 GN=TMED10 PE=1 SV=2 4.03 3632.5 - 761487 - - - -0.5361 - 4.375 0.68 - 1191.7 1 2 0 -0.0011 21 0 0 0 1.47E+07 6.80E+06 - - - 7.6917 0.9935 221125_WJC_METTL3_EV_vs_WT_F03.23138.23138.2 0.19 30-Aug R.EC[160.03]SLQVPEDELVSTLK.Q "sp|P11441|UBL4A_HUMAN,tr|Q5HY81|Q5HY81_HUMAN,tr|F8WB70|F8WB70_HUMAN" 3 1845.903 6.45 37698 23138 2 1845.905892 923.9588 Ubiquitin-like protein 4A OS=Homo sapiens OX=9606 GN=UBL4A PE=1 SV=1 4 3632.8 - 599205 - - - 1.5694 - 1.34 0.213 - 94.6 1 2 0 0.0029 16 0 0 0 7.65E+06 1.19E+06 - - - 1.3329 1 221125_WJC_METTL3_EV_vs_WT_F03.23144.23144.3 8.24E-07 18/60 K.LTTLPSDFC[160.03]GLTHLVK[136.11].L sp|Q96AG4|LRC59_HUMAN 1 1808.9586 1.55 37702 23144 3 1808.95914 603.9935 Leucine-rich repeat-containing protein 59 OS=Homo sapiens OX=9606 GN=LRRC59 PE=1 SV=1 6.73 3633.4 - 6.48E+06 - - - 0.2946 - 2.913 0.588 - 429.8 1 2 0 0.0005 16 0 0 0 1.46E+08 9.44E+07 - - - 7.8389 0.9999 221125_WJC_METTL3_EV_vs_WT_F03.23146.23146.3 2.00E-05 14/48 R.AQFEGIVTDLIR[166.11]R[166.11].T "sp|P38646|GRP75_HUMAN,tr|H0Y8K0|H0Y8K0_HUMAN,tr|A0A7I2V2S7|A0A7I2V2S7_HUMAN,tr|A0A7I2V2G2|A0A7I2V2G2_HUMAN,tr|A0A7I2V3F7|A0A7I2V3F7_HUMAN,tr|A0A7I2YQB2|A0A7I2YQB2_HUMAN,tr|D6RCD7|D6RCD7_HUMAN" 7 1536.8527 0.29 37704 23146 3 1536.850774 513.2915 "Stress-70 protein, mitochondrial OS=Homo sapiens OX=9606 GN=HSPA9 PE=1 SV=2" 6.12 3633.6 - 2.36E+06 - - - -1.2643 - 2.281 0.431 - 312 1 2 0 -0.0019 13 0 0 0 9.84E+06 3.35E+07 - - - 5.5805 1 221125_WJC_METTL3_EV_vs_WT_F03.23147.23147.2 3.13E-10 22/46 R.VETGVLK[136.11]PGMVVTFAPVNVTTEVK[136.11].S "sp|P68104|EF1A1_HUMAN,sp|Q5VTE0|EF1A3_HUMAN,tr|A0A7I2V659|A0A7I2V659_HUMAN,tr|A0A7I2V3H3|A0A7I2V3H3_HUMAN,tr|A0A7I2V5N4|A0A7I2V5N4_HUMAN,tr|A0A087WVQ9|A0A087WVQ9_HUMAN" 6 2530.4051 0.37 37705 23147 2 2530.407246 1266.2099 Elongation factor 1-alpha 1 OS=Homo sapiens OX=9606 GN=EEF1A1 PE=1 SV=1 6.11 3633.7 - 1.79E+06 - - - 0.8291 - 4.437 0.694 - 947.5 1 2 0 0.0021 24 0 0 0 6.79E+06 1.82E+07 - - - 7.8294 1 221125_WJC_METTL3_EV_vs_WT_F03.23149.23149.3 3.87E-09 18/92 K.YIAENGTDPINNQPLSEEQLIDIK[136.11].V "sp|Q9UMS4|PRP19_HUMAN,tr|F5GY56|F5GY56_HUMAN" 2 2721.3589 1.48 37707 23149 3 2721.358678 908.1269 Pre-mRNA-processing factor 19 OS=Homo sapiens OX=9606 GN=PRPF19 PE=1 SV=1 3.83 3633.9 - 1.63E+06 - - - -0.0654 - 3.129 0.628 - 266.7 1 2 0 -0.0002 24 0 0 0 1.62E+08 1.09E+08 - - - 8.1909 0.9875 221125_WJC_METTL3_EV_vs_WT_F03.23150.23150.4 6.79E-07 20/114 A.LILHDDEVTVTEDKINALIK.A sp|P05386|RLA1_HUMAN 1 2278.242 2.02 37708 23150 4 2278.243943 570.5678 60S acidic ribosomal protein P1 OS=Homo sapiens OX=9606 GN=RPLP1 PE=1 SV=1 4.43 3634 - 1.08E+06 - - - 0.8406 - 3.439 0.518 - 272.8 1 1 1 0.0019 20 0 0 0 7.33E+06 3.62E+06 - - - 4.1471 1 221125_WJC_METTL3_EV_vs_WT_F03.23151.23151.3 6.66E-05 16/48 R.AQFEGIVTDLIRR.T "sp|P38646|GRP75_HUMAN,tr|H0Y8K0|H0Y8K0_HUMAN,tr|A0A7I2V2S7|A0A7I2V2S7_HUMAN,tr|A0A7I2V2G2|A0A7I2V2G2_HUMAN,tr|A0A7I2V3F7|A0A7I2V3F7_HUMAN,tr|A0A7I2YQB2|A0A7I2YQB2_HUMAN,tr|D6RCD7|D6RCD7_HUMAN" 7 1516.8362 0.3 37709 23151 3 1516.837771 506.6193 "Stress-70 protein, mitochondrial OS=Homo sapiens OX=9606 GN=HSPA9 PE=1 SV=2" 6.12 3634.2 - 961069 - - - 1.0509 - 2.591 0.517 - 421.1 1 2 0 0.0016 13 0 0 0 9.84E+06 3.24E+07 - - - 6.8849 0.9999 221125_WJC_METTL3_EV_vs_WT_F03.23153.23153.3 9.16E-05 14/60 K.STLLGVLTHGELDNGR.G "sp|O00178|GTPB1_HUMAN,tr|F5H716|F5H716_HUMAN" 2 1680.8795 0.83 37711 23153 3 1680.879935 561.3004 GTP-binding protein 1 OS=Homo sapiens OX=9606 GN=GTPBP1 PE=1 SV=3 5.3 3634.4 - 886572 - - - 0.26 - 2.732 0.356 - 239 1 2 0 0.0004 16 0 0 0 6.59E+06 7.90E+06 - - - 5.0877 1 221125_WJC_METTL3_EV_vs_WT_F03.23160.23160.2 5.34E-07 19/32 K.ELTTEIDNNIEQISSYK.S "sp|P13645|K1C10_HUMAN,tr|A0A1B0GVI3|A0A1B0GVI3_HUMAN" 2 1995.9637 4836.12 37716 23160 2 1995.960995 998.9891 "Keratin, type I cytoskeletal 10 OS=Homo sapiens OX=9606 GN=KRT10 PE=1 SV=6" 4 3635.4 - 4.34E+07 - - - -1.3457 - 3.693 0.641 - 1043.1 1 2 0 -0.0027 17 0 0 0 1.15E+09 2.38E+05 - - - 6.9865 0.9999 221125_WJC_METTL3_EV_vs_WT_F03.23163.23163.3 8.48E-09 18/80 R.GPGNPVPGPLAPLPDYMSEEK.L "sp|Q6P2Q9|PRP8_HUMAN,tr|I3L0J9|I3L0J9_HUMAN" 2 2164.0511 0.67 37719 23163 3 2164.041613 722.3576 Pre-mRNA-processing-splicing factor 8 OS=Homo sapiens OX=9606 GN=PRPF8 PE=1 SV=2 4.14 3635.6 - 1.36E+06 - - - -4.3636 - 3.32 0.57 - 253.9 1 2 0 -0.0094 21 0 0 0 1.62E+07 2.40E+07 - - - 7.7692 1 221125_WJC_METTL3_EV_vs_WT_F03.23164.23164.2 2.71E-08 16/32 K.TVNELQNLTSAEVIVPR[166.11].D "sp|Q9Y6M1|IF2B2_HUMAN,tr|F8W930|F8W930_HUMAN" 2 1892.0243 1.16 37720 23164 2 1892.018443 947.0194 Insulin-like growth factor 2 mRNA-binding protein 2 OS=Homo sapiens OX=9606 GN=IGF2BP2 PE=1 SV=2 4.53 3635.7 - 1.19E+06 - - - -3.0755 - 3.46 0.6 - 701.5 1 2 0 -0.0058 17 0 0 0 1.40E+07 1.21E+07 - - - 6.5225 0.9998 221125_WJC_METTL3_EV_vs_WT_F03.23165.23165.2 3.52E-06 28-Dec K.QISNLQQSISDAEQR.G sp|P04264|K2C1_HUMAN 1 1715.8438 999 37721 23165 2 1715.841881 858.9292 "Keratin, type II cytoskeletal 1 OS=Homo sapiens OX=9606 GN=KRT1 PE=1 SV=6" 4.37 3635.8 - 1.15E+06 - - - -1.1423 - 2.083 0.499 - 410.1 1 2 0 -0.002 15 0 0 0 1.95E+07 0.00E+00 - - - 4.5301 1 221125_WJC_METTL3_EV_vs_WT_F03.23166.23166.3 1.13E-09 23/84 R.EALGLGPPAAQLTPPPAPVGLR[166.11].G "sp|Q8IY67|RAVR1_HUMAN,tr|E9PAU2|E9PAU2_HUMAN,tr|A0A087WZ13|A0A087WZ13_HUMAN" 3 2131.2029 1.04 37722 23166 3 2131.200104 711.4082 Ribonucleoprotein PTB-binding 1 OS=Homo sapiens OX=9606 GN=RAVER1 PE=1 SV=1 6.1 3636 - 942260 - - - -1.3096 - 4.108 0.4 - 467.6 1 2 0 -0.0028 22 0 0 0 1.30E+07 1.25E+07 - - - 6.3487 0.9992 221125_WJC_METTL3_EV_vs_WT_F03.23167.23167.2 0.00411 20-Nov R.KVEDLFLTFAK.K "sp|Q13813|SPTN1_HUMAN,tr|A0A0D9SF54|A0A0D9SF54_HUMAN,tr|A0A0D9SGF6|A0A0D9SGF6_HUMAN" 3 1309.7282 1.85 37723 23167 2 1309.724644 655.8714 "Spectrin alpha chain, non-erythrocytic 1 OS=Homo sapiens OX=9606 GN=SPTAN1 PE=1 SV=3" 6.07 3636.1 - 480467 - - - -2.7067 - 2.205 0.364 - 331.3 1 2 0 -0.0035 11 0 0 0 3.88E+06 2.10E+06 - - - 3.8675 0.9998 221125_WJC_METTL3_EV_vs_WT_F03.23168.23168.3 6.29E-08 15/52 K.HLTVEELFGTSLPK.E "sp|Q9NPI6|DCP1A_HUMAN,tr|A0A087WT55|A0A087WT55_HUMAN" 2 1569.8403 2.08 37724 23168 3 1569.834195 524.2874 mRNA-decapping enzyme 1A OS=Homo sapiens OX=9606 GN=DCP1A PE=1 SV=3 5.4 3636.2 - 420363 - - - -3.8628 - 2.846 0.458 - 253.8 1 2 0 -0.0061 14 0 0 0 4.57E+07 2.20E+07 - - - 6.4241 0.9999 221125_WJC_METTL3_EV_vs_WT_F03.23169.23169.3 2.84E-05 14/60 K.STLLGVLTHGELDNGR[166.11].G "sp|O00178|GTPB1_HUMAN,tr|F5H716|F5H716_HUMAN" 2 1690.8878 0.79 37725 23169 3 1690.886876 564.6365 GTP-binding protein 1 OS=Homo sapiens OX=9606 GN=GTPBP1 PE=1 SV=3 5.3 3636.4 - 377778 - - - -0.5275 - 2.562 0.392 - 142.4 1 2 0 -0.0009 16 0 0 0 6.28E+06 7.90E+06 - - - 5.3241 1 221125_WJC_METTL3_EV_vs_WT_F03.23173.23173.3 4.31E-09 20/92 K.YIAENGTDPINNQPLSEEQLIDIK.V "sp|Q9UMS4|PRP19_HUMAN,tr|F5GY56|F5GY56_HUMAN" 2 2713.3447 1.49 37727 23173 3 2713.343917 905.4555 Pre-mRNA-processing factor 19 OS=Homo sapiens OX=9606 GN=PRPF19 PE=1 SV=1 3.83 3636.9 - 7.55E+06 - - - -0.2724 - 2.997 0.593 - 186 1 2 0 -0.0007 24 0 0 0 1.63E+08 1.09E+08 - - - 7.7005 1 221125_WJC_METTL3_EV_vs_WT_F03.23175.23175.3 4.15E-07 27/80 R.TPAVEGLTEAEEEELRAELTK.V "sp|O43399|TPD54_HUMAN,tr|A0A087WZ51|A0A087WZ51_HUMAN,tr|A0A087WYR3|A0A087WYR3_HUMAN" 3 2314.154 2.21 37729 23175 3 2314.152715 772.3919 Tumor protein D54 OS=Homo sapiens OX=9606 GN=TPD52L2 PE=1 SV=2 4.11 3637 - 3.65E+06 - - - -0.5557 - 5.504 0.641 - 795.1 1 2 1 -0.0013 21 0 0 0 5.53E+07 2.51E+07 - - - 9.775 0.9999 221125_WJC_METTL3_EV_vs_WT_F03.23177.23177.3 1.95E-05 14/48 R.DPILFPSFIHSQK.R sp|P04040|CATA_HUMAN 1 1527.8086 20.78 37731 23177 3 1527.806042 510.2768 Catalase OS=Homo sapiens OX=9606 GN=CAT PE=1 SV=3 6.74 3637.3 - 990523 - - - -1.6514 - 2.798 0.438 - 296.7 1 2 0 -0.0025 13 0 0 0 1.29E+07 6.22E+05 - - - 6.2122 0.9998 221125_WJC_METTL3_EV_vs_WT_F03.23180.23180.3 0.000439 Sep-40 R.K[136.11]VEDLFLTFAK[136.11].K "sp|Q13813|SPTN1_HUMAN,tr|A0A0D9SF54|A0A0D9SF54_HUMAN,tr|A0A0D9SGF6|A0A0D9SGF6_HUMAN" 3 1325.7566 1.02 37734 23180 3 1325.755854 442.9261 "Spectrin alpha chain, non-erythrocytic 1 OS=Homo sapiens OX=9606 GN=SPTAN1 PE=1 SV=3" 6.07 3637.6 - 388094 - - - -0.5544 - 1.753 0.396 - 75 1 2 0 -0.0007 11 0 0 0 8.28E+06 8.14E+06 - - - 4.5494 0.9999 221125_WJC_METTL3_EV_vs_WT_F03.23184.23184.3 1.23E-11 18/64 K.AAIDWFDGKEFSGNPIK.V "sp|P35637|FUS_HUMAN,tr|H3BPE7|H3BPE7_HUMAN" 2 1893.9261 1.07 37736 23184 3 1893.925887 632.316 RNA-binding protein FUS OS=Homo sapiens OX=9606 GN=FUS PE=1 SV=1 4.56 3638.1 - 9.42E+06 - - - -0.1199 - 3.642 0.545 - 523.6 1 2 1 -0.0002 17 0 0 0 5.77E+08 5.41E+08 - - - 7.8815 1 221125_WJC_METTL3_EV_vs_WT_F03.23186.23186.3 5.11E-09 17/64 K.ELTTEIDNNIEQISSYK.S "sp|P13645|K1C10_HUMAN,tr|A0A1B0GVI3|A0A1B0GVI3_HUMAN" 2 1995.9637 1565.63 37738 23186 3 1995.962128 666.3285 "Keratin, type I cytoskeletal 10 OS=Homo sapiens OX=9606 GN=KRT10 PE=1 SV=6" 4 3638.1 - 1.08E+08 - - - -0.7781 - 2.823 0.504 - 339.1 1 2 0 -0.0016 17 0 0 0 1.30E+09 8.30E+05 - - - 6.7805 0.9999 221125_WJC_METTL3_EV_vs_WT_F03.23188.23188.3 0.00218 13/56 K.EAAASGLPLMVIIHK.S sp|O95881|TXD12_HUMAN 1 1548.8698 1.31 37740 23188 3 1548.869518 517.2972 Thioredoxin domain-containing protein 12 OS=Homo sapiens OX=9606 GN=TXNDC12 PE=1 SV=1 6.85 3638.2 - 4.09E+06 - - - -0.1724 - 2.414 0.425 - 317.1 1 2 0 -0.0003 15 0 0 0 4.50E+08 3.43E+08 - - - 5.5779 0.9993 221125_WJC_METTL3_EV_vs_WT_F03.23189.23189.3 0.00011 Nov-68 R.FTPGTFTNQIQAAFR[166.11]EPR[166.11].L "sp|P08865|RSSA_HUMAN,tr|C9J9K3|C9J9K3_HUMAN,tr|A0A0C4DG17|A0A0C4DG17_HUMAN" 3 2100.0656 1.17 37741 23189 3 2100.067429 701.0291 40S ribosomal protein SA OS=Homo sapiens OX=9606 GN=RPSA PE=1 SV=4 9.6 3638.4 - 984615 - - - 0.8885 - 2.434 0.371 - 143.8 1 2 1 0.0019 18 0 0 0 2.94E+07 2.52E+07 - - - 4.8908 1 221125_WJC_METTL3_EV_vs_WT_F03.23191.23191.3 3.53E-08 16/64 R.SMDELNHDFQALALEGR[166.11].A "sp|Q14671|PUM1_HUMAN,tr|Q5T1Z8|Q5T1Z8_HUMAN,tr|H0YEH2|H0YEH2_HUMAN,tr|Q5T1Z4|Q5T1Z4_HUMAN,tr|E9PR38|E9PR38_HUMAN" 5 1954.9082 2.48 37743 23191 3 1954.906953 652.6434 Pumilio homolog 1 OS=Homo sapiens OX=9606 GN=PUM1 PE=1 SV=3 4.31 3638.6 - 583295 - - - -0.6609 - 3.196 0.581 - 348.7 1 2 0 -0.0013 17 0 0 0 2.19E+08 8.80E+07 - - - 7.9525 1 221125_WJC_METTL3_EV_vs_WT_F03.23195.23195.3 4.50E-14 17/64 R.SMDELNHDFQALALEGR.A "sp|Q14671|PUM1_HUMAN,tr|Q5T1Z8|Q5T1Z8_HUMAN,tr|H0YEH2|H0YEH2_HUMAN,tr|Q5T1Z4|Q5T1Z4_HUMAN,tr|E9PR38|E9PR38_HUMAN" 5 1944.9 2.48 37745 23195 3 1944.898814 649.3073 Pumilio homolog 1 OS=Homo sapiens OX=9606 GN=PUM1 PE=1 SV=3 4.31 3639.1 - 3.66E+06 - - - -0.5969 - 3.524 0.686 - 336.3 1 2 0 -0.0012 17 0 0 0 2.19E+08 8.80E+07 - - - 9.37 1 221125_WJC_METTL3_EV_vs_WT_F03.23196.23196.3 8.21E-07 16/52 K.HLTVEELFGTSLPK[136.11].E "sp|Q9NPI6|DCP1A_HUMAN,tr|A0A087WT55|A0A087WT55_HUMAN" 2 1577.8545 2.08 37746 23196 3 1577.854521 526.9588 mRNA-decapping enzyme 1A OS=Homo sapiens OX=9606 GN=DCP1A PE=1 SV=3 5.4 3639.2 - 1.99E+06 - - - 0.0393 - 2.918 0.492 - 337.7 1 2 0 0.0001 14 0 0 0 4.57E+07 2.20E+07 - - - 6.8712 1 221125_WJC_METTL3_EV_vs_WT_F03.23199.23199.2 3.28E-07 15/32 K.MSSSDTPLGTVALLQEK.Q sp|O43290|SNUT1_HUMAN 1 1775.8975 2.68 37749 23199 2 1775.898994 888.956 U4\U6.U5 tri-snRNP-associated protein 1 OS=Homo sapiens OX=9606 GN=SART1 PE=1 SV=1 4.37 3639.5 - 1.09E+06 - - - 0.8323 - 3.342 0.606 - 560 1 2 0 0.0015 17 0 0 0 1.87E+07 6.98E+06 - - - 6.4829 1 221125_WJC_METTL3_EV_vs_WT_F03.23200.23200.2 1.12E-11 19/32 K.AAIDWFDGKEFSGNPIK.V "sp|P35637|FUS_HUMAN,tr|H3BPE7|H3BPE7_HUMAN" 2 1893.9261 1.1 37750 23200 2 1893.930028 947.9703 RNA-binding protein FUS OS=Homo sapiens OX=9606 GN=FUS PE=1 SV=1 4.56 3639.6 - 968597 - - - 2.0666 - 4.041 0.648 - 1405.2 1 2 1 0.0039 17 0 0 0 3.64E+07 3.32E+07 - - - 7.2592 0.9992 221125_WJC_METTL3_EV_vs_WT_F03.23201.23201.2 0.00744 30-Dec K.AAPQPLNLVSSVTLSK[136.11].S "sp|Q9H334|FOXP1_HUMAN,tr|A0A3B3ISQ6|A0A3B3ISQ6_HUMAN,tr|A0A3B3IRW5|A0A3B3IRW5_HUMAN,tr|G5E965|G5E965_HUMAN,tr|A0A3B3IRS5|A0A3B3IRS5_HUMAN,tr|A0A3B3IST0|A0A3B3IST0_HUMAN,tr|A0A3B3IT14|A0A3B3IT14_HUMAN,tr|C9J0F0|C9J0F0_HUMAN,tr|A0A3B3IUB6|A0A3B3IUB6_HUMAN,tr|H0Y882|H0Y882_HUMAN,tr|A0A3B3IT66|A0A3B3IT66_HUMAN,tr|A0A3B3IS87|A0A3B3IS87_HUMAN,tr|A0A0B4J2F3|A0A0B4J2F3_HUMAN,tr|A0A3B3IST6|A0A3B3IST6_HUMAN" 14 1631.9338 3.78 37751 23201 2 1631.934183 816.9742 Forkhead box protein P1 OS=Homo sapiens OX=9606 GN=FOXP1 PE=1 SV=1 8.8 3639.7 - 951942 - - - 0.2518 - 1.642 0.312 - 222.9 1 2 0 0.0004 16 0 0 0 8.63E+07 2.28E+07 - - - 2.5645 1 221125_WJC_METTL3_EV_vs_WT_F03.23202.23202.2 8.88E-10 19/46 K.YIAENGTDPINNQPLSEEQLIDIK.V "sp|Q9UMS4|PRP19_HUMAN,tr|F5GY56|F5GY56_HUMAN" 2 2713.3447 1.76 37752 23202 2 2713.346669 1357.6796 Pre-mRNA-processing factor 19 OS=Homo sapiens OX=9606 GN=PRPF19 PE=1 SV=1 3.83 3639.9 - 856600 - - - 0.7419 - 3.726 0.691 - 661.3 1 2 0 0.002 24 0 0 0 8.94E+06 5.07E+06 - - - 7.3779 1 221125_WJC_METTL3_EV_vs_WT_F03.23204.23204.3 1.18E-07 18/56 K.VSNLQYLHSYLTYIK[136.11].L sp|Q9UHB9|SRP68_HUMAN 1 1848.9865 1.2 37754 23204 3 1848.989439 617.3361 Signal recognition particle subunit SRP68 OS=Homo sapiens OX=9606 GN=SRP68 PE=1 SV=2 8.41 3640.1 - 629744 - - - 1.57 - 3.502 0.5 - 401.2 1 2 0 0.0029 15 0 0 0 1.74E+07 1.44E+07 - - - 7.3841 0.9999 221125_WJC_METTL3_EV_vs_WT_F03.23207.23207.3 6.27E-05 16/44 K.ITQDIFQQLLKR.G "sp|P56192|SYMC_HUMAN,tr|H0YHV5|H0YHV5_HUMAN" 2 1501.8617 0.86 37757 23207 3 1501.86231 501.6278 "Methionine--tRNA ligase, cytoplasmic OS=Homo sapiens OX=9606 GN=MARS1 PE=1 SV=2" 8.75 3640.5 - 504687 - - - 0.4308 - 2.667 0.4 - 351.4 1 2 0 0.0006 12 0 0 0 4.46E+06 5.19E+06 - - - 5.7185 1 221125_WJC_METTL3_EV_vs_WT_F03.23209.23209.3 1.78E-06 15/64 R.SPPTPTGLVHLVVVAAK.K sp|Q8IYS2|K2013_HUMAN 1 1684.9876 1.13 37759 23209 3 1684.988561 562.6698 Uncharacterized protein KIAA2013 OS=Homo sapiens OX=9606 GN=KIAA2013 PE=1 SV=1 8.49 3640.8 - 357438 - - - 0.5751 - 2.783 0.53 - 207 1 2 0 0.001 17 0 0 0 2.85E+07 2.53E+07 - - - 7.0345 1 221125_WJC_METTL3_EV_vs_WT_F03.23211.23211.2 3.49E-11 21/32 K.AAIDWFDGK[136.11]EFSGNPIK[136.11].V "sp|P35637|FUS_HUMAN,tr|H3BPE7|H3BPE7_HUMAN" 2 1909.9545 1.1 37760 23211 2 1909.952021 955.9845 RNA-binding protein FUS OS=Homo sapiens OX=9606 GN=FUS PE=1 SV=1 4.56 3641 - 3.08E+06 - - - -1.3053 - 4.347 0.585 - 1880.1 1 2 1 -0.0025 17 0 0 0 3.64E+07 3.32E+07 - - - 6.9738 0.9998 221125_WJC_METTL3_EV_vs_WT_F03.23215.23215.2 0.00194 22-Nov K.TVEDYFC[160.03]FC[160.03]YGK.A "sp|P78347|GTF2I_HUMAN,tr|A0A494C1K3|A0A494C1K3_HUMAN" 2 1587.6374 1.25 37763 23215 2 1587.635626 794.826 General transcription factor II-I OS=Homo sapiens OX=9606 GN=GTF2I PE=1 SV=2 4.37 3641.4 - 2.34E+06 - - - -1.1186 - 1.969 0.543 - 255.3 1 2 0 -0.0018 12 0 0 0 2.54E+07 2.03E+07 - - - 4.8337 1 221125_WJC_METTL3_EV_vs_WT_F03.23216.23216.2 7.40E-07 22-Oct K.TVEDYFC[160.03]FC[160.03]YGK[136.11].A "sp|P78347|GTF2I_HUMAN,tr|A0A494C1K3|A0A494C1K3_HUMAN" 2 1595.6516 1.25 37764 23216 2 1595.653119 798.8331 General transcription factor II-I OS=Homo sapiens OX=9606 GN=GTF2I PE=1 SV=2 4.37 3641.5 - 1.79E+06 - - - 0.9507 - 2.096 0.69 - 198.6 1 2 0 0.0015 12 0 0 0 2.54E+07 2.03E+07 - - - 6.084 0.9999 221125_WJC_METTL3_EV_vs_WT_F03.23220.23220.2 8.95E-06 20/30 K.NEVLMVNIGSLSTGGR[166.11].V "sp|Q2VIR3|IF2GL_HUMAN,sp|P41091|IF2G_HUMAN" 2 1655.854 0.94 37768 23220 2 1655.856097 828.9343 Eukaryotic translation initiation factor 2 subunit 3B OS=Homo sapiens OX=9606 GN=EIF2S3B PE=2 SV=2 6 3641.9 - 941332 - - - 1.2513 - 3.172 0.49 - 1451.6 1 2 0 0.0021 16 0 0 0 2.85E+07 3.03E+07 - - - 5.4975 1 221125_WJC_METTL3_EV_vs_WT_F03.23223.23223.2 2.06E-10 15/26 R.DGPASEAALQLLC[160.03]R.A "sp|Q5TA31|RN187_HUMAN,tr|A0A1X7SBW3|A0A1X7SBW3_HUMAN" 2 1499.7402 999 37771 23223 2 1499.744898 750.8774 E3 ubiquitin-protein ligase RNF187 OS=Homo sapiens OX=9606 GN=RNF187 PE=1 SV=2 4.37 3642.3 - 625963 - - - 3.1139 - 3.189 0.665 - 964.4 1 2 0 0.0047 14 0 0 0 4.35E+06 0.00E+00 - - - 6.8615 0.9995 221125_WJC_METTL3_EV_vs_WT_F03.23224.23224.3 0.00979 Oct-40 K.DLVDYITTHYK.G "sp|O75439|MPPB_HUMAN,tr|F8WAZ6|F8WAZ6_HUMAN,tr|G3V0E4|G3V0E4_HUMAN" 3 1366.6769 1.1 37772 23224 3 1366.676712 456.5662 Mitochondrial-processing peptidase subunit beta OS=Homo sapiens OX=9606 GN=PMPCB PE=1 SV=2 5.21 3642.4 - 446580 - - - -0.1244 - 1.977 0.298 - 111.5 1 2 0 -0.0002 11 0 0 0 5.38E+06 4.88E+06 - - - 3.7986 1 221125_WJC_METTL3_EV_vs_WT_F03.23227.23227.3 7.92E-13 18/64 K.AAIDWFDGK[136.11]EFSGNPIK[136.11].V "sp|P35637|FUS_HUMAN,tr|H3BPE7|H3BPE7_HUMAN" 2 1909.9545 1.07 37774 23227 3 1909.952576 637.6588 RNA-binding protein FUS OS=Homo sapiens OX=9606 GN=FUS PE=1 SV=1 4.56 3642.8 - 7.90E+07 - - - -1.0147 - 3.765 0.6 - 509 1 2 1 -0.0019 17 0 0 0 5.76E+08 5.39E+08 - - - 8.5781 1 221125_WJC_METTL3_EV_vs_WT_F03.23229.23229.3 2.07E-11 19/80 R.LKDIALGMQTEIEEQDDILDR.L "sp|O95721|SNP29_HUMAN,tr|C9JAF7|C9JAF7_HUMAN" 2 2444.2105 1.21 37775 23229 3 2444.206499 815.7441 Synaptosomal-associated protein 29 OS=Homo sapiens OX=9606 GN=SNAP29 PE=1 SV=1 3.9 3643 - 2.76E+06 - - - -1.6247 - 3.698 0.622 - 544.5 1 2 1 -0.004 21 0 0 0 8.74E+06 7.24E+06 - - - 8.609 0.9998 221125_WJC_METTL3_EV_vs_WT_F03.23230.23230.3 2.87E-06 14/56 K.EVGVYEALKDDSWLK.G "sp|P40925|MDHC_HUMAN,tr|A0A5K1VW95|A0A5K1VW95_HUMAN,tr|B8ZZ51|B8ZZ51_HUMAN,tr|B9A041|B9A041_HUMAN" 4 1750.8778 1.23 37776 23230 3 1750.877258 584.6332 "Malate dehydrogenase, cytoplasmic OS=Homo sapiens OX=9606 GN=MDH1 PE=1 SV=4" 4.32 3643.1 - 1.61E+06 - - - -0.2907 - 2.814 0.456 - 208.2 1 2 1 -0.0005 15 0 0 0 1.38E+07 1.12E+07 - - - 6.3235 0.9999 221125_WJC_METTL3_EV_vs_WT_F03.23231.23231.3 0.00018 15/56 K.EVGVYEALK[136.11]DDSWLK[136.11].G "sp|P40925|MDHC_HUMAN,tr|A0A5K1VW95|A0A5K1VW95_HUMAN,tr|B8ZZ51|B8ZZ51_HUMAN,tr|B9A041|B9A041_HUMAN" 4 1766.9062 1.23 37777 23231 3 1766.905516 589.976 "Malate dehydrogenase, cytoplasmic OS=Homo sapiens OX=9606 GN=MDH1 PE=1 SV=4" 4.32 3643.1 - 1.51E+06 - - - -0.3684 - 2.856 0.499 - 267 1 2 1 -0.0007 15 0 0 0 1.38E+07 1.12E+07 - - - 6.8415 1 221125_WJC_METTL3_EV_vs_WT_F03.23232.23232.2 1.68E-10 21/26 K.HLTVEELFGTSLPK.E "sp|Q9NPI6|DCP1A_HUMAN,tr|A0A087WT55|A0A087WT55_HUMAN" 2 1569.8403 3.47 37778 23232 2 1569.843485 785.9274 mRNA-decapping enzyme 1A OS=Homo sapiens OX=9606 GN=DCP1A PE=1 SV=3 5.4 3643.2 - 1.23E+06 - - - 2.055 - 3.635 0.646 - 1280.8 1 2 0 0.0032 14 0 0 0 1.07E+07 3.07E+06 - - - 7.0501 1 221125_WJC_METTL3_EV_vs_WT_F03.23233.23233.2 3.95E-10 18/32 R.SMDELNHDFQALALEGR.A "sp|Q14671|PUM1_HUMAN,tr|Q5T1Z8|Q5T1Z8_HUMAN,tr|H0YEH2|H0YEH2_HUMAN,tr|Q5T1Z4|Q5T1Z4_HUMAN,tr|E9PR38|E9PR38_HUMAN" 5 1944.9 2.45 37779 23233 2 1944.90511 973.4573 Pumilio homolog 1 OS=Homo sapiens OX=9606 GN=PUM1 PE=1 SV=3 4.31 3643.4 - 1.01E+06 - - - 2.6402 - 4.194 0.724 - 841.8 1 2 0 0.0051 17 0 0 0 9.10E+06 3.71E+06 - - - 7.9116 0.9915 221125_WJC_METTL3_EV_vs_WT_F03.23238.23238.2 0.000172 13/20 H.NLQSIFNIGSR.G "sp|P43243|MATR3_HUMAN,tr|A8MXP9|A8MXP9_HUMAN,tr|D6R991|D6R991_HUMAN,tr|D6REK4|D6REK4_HUMAN,tr|A0A0R4J2E8|A0A0R4J2E8_HUMAN,tr|D6RCM3|D6RCM3_HUMAN,tr|D6R8Z5|D6R8Z5_HUMAN,tr|D6REM6|D6REM6_HUMAN" 8 1247.6622 1.23 37784 23238 2 1247.662713 624.8384 Matrin-3 OS=Homo sapiens OX=9606 GN=MATR3 PE=1 SV=2 9.75 3644 - 613599 - - - 0.3831 - 2.221 0.47 - 677.2 1 1 0 0.0005 11 0 0 0 1.87E+07 1.52E+07 - - - 4.6709 0.9999 221125_WJC_METTL3_EV_vs_WT_F03.23239.23239.3 0.00113 Oct-40 K.DLVDYITTHYK[136.11].G "sp|O75439|MPPB_HUMAN,tr|F8WAZ6|F8WAZ6_HUMAN,tr|G3V0E4|G3V0E4_HUMAN" 3 1374.6911 1.07 37785 23239 3 1374.690916 459.2376 Mitochondrial-processing peptidase subunit beta OS=Homo sapiens OX=9606 GN=PMPCB PE=1 SV=2 5.21 3644.1 - 539509 - - - -0.1208 - 1.836 0.44 - 110.3 1 2 0 -0.0002 11 0 0 0 5.38E+06 5.02E+06 - - - 5.1716 0.9999 221125_WJC_METTL3_EV_vs_WT_F03.23241.23241.4 0.000293 20/96 R.SLLEAVSFLHANNIVHR[166.11].D "sp|P15735|PHKG2_HUMAN,tr|J3KNN3|J3KNN3_HUMAN,tr|H3BTW6|H3BTW6_HUMAN,tr|H3BP07|H3BP07_HUMAN,tr|H3BTI9|H3BTI9_HUMAN" 5 1929.046 0.92 37787 23241 4 1929.044267 483.2688 "Phosphorylase b kinase gamma catalytic chain, liver\testis isoform OS=Homo sapiens OX=9606 GN=PHKG2 PE=1 SV=1" 6.66 3644.4 - 505778 - - - -0.8984 - 3.332 0.457 - 220 1 2 0 -0.0017 17 0 0 0 5.17E+06 5.60E+06 - - - 3.6211 1 221125_WJC_METTL3_EV_vs_WT_F03.23242.23242.2 2.09E-12 19/32 R.SMDELNHDFQALALEGR[166.11].A "sp|Q14671|PUM1_HUMAN,tr|Q5T1Z8|Q5T1Z8_HUMAN,tr|H0YEH2|H0YEH2_HUMAN,tr|Q5T1Z4|Q5T1Z4_HUMAN,tr|E9PR38|E9PR38_HUMAN" 5 1954.9082 2.45 37788 23242 2 1954.90976 978.4614 Pumilio homolog 1 OS=Homo sapiens OX=9606 GN=PUM1 PE=1 SV=3 4.31 3644.5 - 449595 - - - 0.775 - 3.792 0.731 - 1037.1 1 2 0 0.0015 17 0 0 0 9.10E+06 3.71E+06 - - - 7.7167 0.9939 221125_WJC_METTL3_EV_vs_WT_F03.23243.23243.4 0.0135 Nov-90 R.FIHNSHDLTYFAYLIK[136.11].A sp|O60343|TBCD4_HUMAN 1 1989.024 0.68 37789 23243 4 1989.02533 498.2633 TBC1 domain family member 4 OS=Homo sapiens OX=9606 GN=TBC1D4 PE=1 SV=2 6.92 3644.6 - 436299 - - - 0.6767 - 1.921 0.217 - 127.6 1 2 0 0.0013 16 0 0 0 2.03E+06 2.98E+06 - - - 1.3444 1 221125_WJC_METTL3_EV_vs_WT_F03.23247.23247.3 3.25E-09 24/80 R.SINDPEHPLTLEELNVVEQVR.V "sp|Q9Y3D0|CIA2B_HUMAN,tr|H3BNV7|H3BNV7_HUMAN,tr|J3KS95|J3KS95_HUMAN" 3 2430.2391 3.27 37791 23247 3 2430.240749 811.087 Cytosolic iron-sulfur assembly component 2B OS=Homo sapiens OX=9606 GN=CIAO2B PE=1 SV=1 4.25 3645.1 - 4.35E+06 - - - 0.6917 - 3.692 0.634 - 666.2 1 2 0 0.0017 21 0 0 0 4.23E+07 1.29E+07 - - - 8.7395 1 221125_WJC_METTL3_EV_vs_WT_F03.23249.23249.3 1.73E-06 Nov-64 R.KLFIGGLSFETTEESLR.N "sp|P22626|ROA2_HUMAN,tr|A0A7I2YQN4|A0A7I2YQN4_HUMAN,tr|A0A7I2V4N0|A0A7I2V4N0_HUMAN,tr|A0A7I2V4N1|A0A7I2V4N1_HUMAN,tr|A0A7I2V4I6|A0A7I2V4I6_HUMAN,tr|A0A087WUI2|A0A087WUI2_HUMAN,tr|A0A7I2V4S4|A0A7I2V4S4_HUMAN,tr|A0A7I2V323|A0A7I2V323_HUMAN,tr|A0A7I2V3P1|A0A7I2V3P1_HUMAN,tr|A0A7I2V3P7|A0A7I2V3P7_HUMAN" 10 1926.0098 1.2 37793 23249 3 1926.009202 643.0106 Heterogeneous nuclear ribonucleoproteins A2\B1 OS=Homo sapiens OX=9606 GN=HNRNPA2B1 PE=1 SV=2 4.79 3645.2 - 3.18E+06 - - - -0.3333 - 2.351 0.489 - 125.5 1 2 0 -0.0006 17 0 0 0 1.02E+08 8.48E+07 - - - 6.1513 1 221125_WJC_METTL3_EV_vs_WT_F03.23250.23250.2 0.0104 18/26 R.GPSADLLEDLSESR.E sp|Q92908|GATA6_HUMAN 1 1487.7104 2.62 37794 23250 2 1487.711329 744.8625 Transcription factor GATA-6 OS=Homo sapiens OX=9606 GN=GATA6 PE=1 SV=2 3.92 3645.3 - 2.28E+06 - - - 0.6466 - 3.646 0.613 - 1636.7 1 2 0 0.001 14 0 0 0 3.72E+07 1.42E+07 - - - 6.8146 0.9881 221125_WJC_METTL3_EV_vs_WT_F03.23253.23253.2 0.416 26-May R.SEAPNWATQDSGFY.- "sp|P60228|EIF3E_HUMAN,tr|H0YBP5|H0YBP5_HUMAN,tr|A0A7I2V5Z6|A0A7I2V5Z6_HUMAN,tr|B3KW56|B3KW56_HUMAN,tr|H0YAW4|H0YAW4_HUMAN,tr|A0A7I2V4B4|A0A7I2V4B4_HUMAN,tr|E5RGA2|E5RGA2_HUMAN,tr|A0A7I2V3I0|A0A7I2V3I0_HUMAN,tr|E5RHS5|E5RHS5_HUMAN,tr|A0A7I2V5P9|A0A7I2V5P9_HUMAN" 10 1571.6529 - 37797 23253 2 1571.653661 786.8337 Eukaryotic translation initiation factor 3 subunit E OS=Homo sapiens OX=9606 GN=EIF3E PE=1 SV=1 3.67 3645.4 - 1.42E+06 - - - 0.5147 - 1.002 0.205 - 51.9 1 2 0 0.0008 14 0 0 0 - - - - - 0.5599 1 221125_WJC_METTL3_EV_vs_WT_F03.23254.23254.3 1.19E-09 19/60 R.GHGAGGASILTFWDAR.L "sp|P0DTE8|AMY1C_HUMAN,sp|P0DTE7|AMY1B_HUMAN,sp|P04746|AMYP_HUMAN,sp|P0DUB6|AMY1A_HUMAN,sp|P19961|AMY2B_HUMAN" 5 1614.7903 2.23 37798 23254 3 1614.788425 539.2707 Alpha-amylase 1C OS=Homo sapiens OX=9606 GN=AMY1C PE=1 SV=1 6.74 3645.6 - 1.08E+06 - - - -1.1543 - 3.011 0.533 - 387.6 1 2 0 -0.0019 16 0 0 0 8.30E+06 3.73E+06 - - - 7.3102 1 221125_WJC_METTL3_EV_vs_WT_F03.23255.23255.3 1.02E-10 21/68 K.LDEIYVAGLVAHSDLDER.A "sp|O60506|HNRPQ_HUMAN,tr|A0A7I2YQV8|A0A7I2YQV8_HUMAN,tr|A0A7I2YQN2|A0A7I2YQN2_HUMAN,tr|A0A7I2V5Q6|A0A7I2V5Q6_HUMAN,tr|A0A7I2V4Z0|A0A7I2V4Z0_HUMAN,tr|A0A7I2V4J0|A0A7I2V4J0_HUMAN,tr|F6UXX1|F6UXX1_HUMAN,tr|A0A7I2V346|A0A7I2V346_HUMAN" 8 2014.0007 1.24 37799 23255 3 2013.994303 672.3409 Heterogeneous nuclear ribonucleoprotein Q OS=Homo sapiens OX=9606 GN=SYNCRIP PE=1 SV=2 4.1 3645.7 - 1.01E+06 - - - -3.1936 - 3.983 0.605 - 588.5 1 2 0 -0.0064 18 0 0 0 1.01E+07 8.14E+06 - - - 8.7248 1 221125_WJC_METTL3_EV_vs_WT_F03.23257.23257.4 3.48E-07 17/96 R.SLLEAVSFLHANNIVHR.D "sp|P15735|PHKG2_HUMAN,tr|J3KNN3|J3KNN3_HUMAN,tr|H3BTW6|H3BTW6_HUMAN,tr|H3BP07|H3BP07_HUMAN,tr|H3BTI9|H3BTI9_HUMAN" 5 1919.0377 0.82 37801 23257 4 1919.035423 480.7667 "Phosphorylase b kinase gamma catalytic chain, liver\testis isoform OS=Homo sapiens OX=9606 GN=PHKG2 PE=1 SV=1" 6.66 3645.9 - 935358 - - - -1.2022 - 3.334 0.583 - 180 1 2 0 -0.0023 17 0 0 0 5.17E+06 6.28E+06 - - - 4.7179 0.9999 221125_WJC_METTL3_EV_vs_WT_F03.23259.23259.3 8.85E-05 14/60 K.NEVLMVNIGSLSTGGR.V "sp|Q2VIR3|IF2GL_HUMAN,sp|P41091|IF2G_HUMAN" 2 1645.8458 6.77 37803 23259 3 1645.843752 549.6225 Eukaryotic translation initiation factor 2 subunit 3B OS=Homo sapiens OX=9606 GN=EIF2S3B PE=2 SV=2 6 3646.2 - 798138 - - - -1.217 - 2.271 0.448 - 210.4 1 2 0 -0.002 16 0 0 0 3.00E+07 4.44E+06 - - - 5.6388 1 221125_WJC_METTL3_EV_vs_WT_F03.23260.23260.3 1.05E-05 15/64 R.SPPTPTGLVHLVVVAAK[136.11].K sp|Q8IYS2|K2013_HUMAN 1 1693.0018 1.13 37804 23260 3 1693.002717 565.3412 Uncharacterized protein KIAA2013 OS=Homo sapiens OX=9606 GN=KIAA2013 PE=1 SV=1 8.49 3646.3 - 723705 - - - 0.5464 - 2.707 0.508 - 192.1 1 2 0 0.0009 17 0 0 0 2.83E+07 2.51E+07 - - - 6.7192 1 221125_WJC_METTL3_EV_vs_WT_F03.23261.23261.2 2.78E-09 30-Dec K.ASGGLPQFGDEYDFYR[166.11].S "sp|Q01780|EXOSX_HUMAN,tr|K7EJ37|K7EJ37_HUMAN" 2 1830.8088 1.26 37805 23261 2 1830.806699 916.4117 Exosome component 10 OS=Homo sapiens OX=9606 GN=EXOSC10 PE=1 SV=2 4.03 3646.4 - 709076 - - - -1.1743 - 2.496 0.678 - 365.8 1 2 0 -0.0022 16 0 0 0 7.51E+06 5.96E+06 - - - 6.2968 1 221125_WJC_METTL3_EV_vs_WT_F03.23263.23263.3 8.82E-10 17/60 K.NEVLMVNIGSLSTGGR[166.11].V "sp|Q2VIR3|IF2GL_HUMAN,sp|P41091|IF2G_HUMAN" 2 1655.854 4.42 37807 23263 3 1655.85388 552.9586 Eukaryotic translation initiation factor 2 subunit 3B OS=Homo sapiens OX=9606 GN=EIF2S3B PE=2 SV=2 6 3646.7 - 503185 - - - -0.0876 - 3.157 0.579 - 399.9 1 2 0 -0.0001 16 0 0 0 1.62E+07 3.66E+06 - - - 7.945 1 221125_WJC_METTL3_EV_vs_WT_F03.23264.23264.3 3.60E-07 13/48 K.KQPALDVLYDVMK.S sp|Q14152|EIF3A_HUMAN 1 1518.8116 0.59 37808 23264 3 1518.808577 507.2778 Eukaryotic translation initiation factor 3 subunit A OS=Homo sapiens OX=9606 GN=EIF3A PE=1 SV=1 5.96 3646.8 - 413275 - - - -1.991 - 2.633 0.506 - 388.8 1 2 0 -0.003 13 0 0 0 2.06E+07 3.48E+07 - - - 6.8054 1 221125_WJC_METTL3_EV_vs_WT_F03.23269.23269.3 3.61E-18 33/100 R.YAQPATATAATAAAAAAAAYSDGYGR.V "sp|O43251|RFOX2_HUMAN,tr|B0QYV1|B0QYV1_HUMAN,tr|A0A0G2JRD1|A0A0G2JRD1_HUMAN,tr|A0A0G2JRA5|A0A0G2JRA5_HUMAN,tr|S4R3K7|S4R3K7_HUMAN" 5 2431.1404 1.33 37811 23269 3 2431.139037 811.3874 RNA binding protein fox-1 homolog 2 OS=Homo sapiens OX=9606 GN=RBFOX2 PE=1 SV=3 5.83 3647.5 - 2.95E+07 - - - -0.5676 - 5.033 0.736 - 1528.4 1 2 0 -0.0014 26 0 0 0 7.16E+08 5.36E+08 - - - 10.4632 1 221125_WJC_METTL3_EV_vs_WT_F03.23271.23271.3 4.26E-05 15/64 K.VTEGLVDVILYHQPDDK.K "sp|O43390|HNRPR_HUMAN,tr|B4DT28|B4DT28_HUMAN,tr|A0A6Q8PHG0|A0A6Q8PHG0_HUMAN,tr|A0A6Q8PH31|A0A6Q8PH31_HUMAN,tr|A0A6Q8PEX7|A0A6Q8PEX7_HUMAN" 5 1939.9891 1.68 37813 23271 3 1939.990666 647.6703 Heterogeneous nuclear ribonucleoprotein R OS=Homo sapiens OX=9606 GN=HNRNPR PE=1 SV=1 4.22 3647.6 - 1.57E+07 - - - 0.8031 - 3.113 0.499 - 268.3 1 2 0 0.0016 17 0 0 0 1.62E+08 9.63E+07 - - - 6.9718 1 221125_WJC_METTL3_EV_vs_WT_F03.23272.23272.2 0.000299 15/22 K.TGELNQLLNAVK[136.11].S "sp|Q15643|TRIPB_HUMAN,tr|H0YJ97|H0YJ97_HUMAN" 2 1306.7336 1.04 37814 23272 2 1306.73332 654.3741 Thyroid receptor-interacting protein 11 OS=Homo sapiens OX=9606 GN=TRIP11 PE=1 SV=3 5.66 3647.6 - 6.06E+06 - - - -0.2258 - 2.819 0.544 - 1048.7 1 2 0 -0.0003 12 0 0 0 1.15E+08 1.11E+08 - - - 5.7858 1 221125_WJC_METTL3_EV_vs_WT_F03.23274.23274.2 4.05E-11 29/50 R.YAQPATATAATAAAAAAAAYSDGYGR.V "sp|O43251|RFOX2_HUMAN,tr|B0QYV1|B0QYV1_HUMAN,tr|A0A0G2JRD1|A0A0G2JRD1_HUMAN,tr|A0A0G2JRA5|A0A0G2JRA5_HUMAN,tr|S4R3K7|S4R3K7_HUMAN" 5 2431.1404 1.43 37816 23274 2 2431.139086 1216.5775 RNA binding protein fox-1 homolog 2 OS=Homo sapiens OX=9606 GN=RBFOX2 PE=1 SV=3 5.83 3647.9 - 1.70E+06 - - - -0.5475 - 5.637 0.727 - 2202.3 1 2 0 -0.0013 26 0 0 0 4.33E+07 3.03E+07 - - - 8.6619 0.9999 221125_WJC_METTL3_EV_vs_WT_F03.23276.23276.3 2.47E-08 15/60 K.SK[136.11]GYAFIEFASFEDAK[136.11].E "sp|P19338|NUCL_HUMAN,tr|A0A7I2V506|A0A7I2V506_HUMAN,tr|A0A7I2V699|A0A7I2V699_HUMAN,tr|A0A7I2V2U7|A0A7I2V2U7_HUMAN,tr|A0A7I2V3F3|A0A7I2V3F3_HUMAN,tr|A0A7I2V428|A0A7I2V428_HUMAN,tr|A0A7I2V349|A0A7I2V349_HUMAN,tr|H7BY16|H7BY16_HUMAN,tr|A0A7I2V5M5|A0A7I2V5M5_HUMAN,tr|C9JLB1|C9JLB1_HUMAN" 10 1824.8905 1.02 37818 23276 3 1824.892302 609.3041 Nucleolin OS=Homo sapiens OX=9606 GN=NCL PE=1 SV=3 4.68 3648 - 1.12E+06 - - - 0.9781 - 3.125 0.549 - 427.6 1 2 1 0.0018 16 0 0 0 2.66E+07 2.60E+07 - - - 7.5839 0.9993 221125_WJC_METTL3_EV_vs_WT_F03.23277.23277.2 0.00149 26-Dec K.ETLTFPPEVPISEK.A sp|Q15208|STK38_HUMAN 1 1585.8239 2.86 37819 23277 2 1585.827815 793.9192 Serine\threonine-protein kinase 38 OS=Homo sapiens OX=9606 GN=STK38 PE=1 SV=1 4.25 3648.1 - 1.11E+06 - - - 2.4435 - 2.206 0.402 - 281.5 1 2 0 0.0039 14 0 0 0 1.89E+07 6.62E+06 - - - 3.9944 1 221125_WJC_METTL3_EV_vs_WT_F03.23279.23279.2 1.67E-08 14/28 R.SNQQLENDLNLMDIK[136.11].L "sp|P46940|IQGA1_HUMAN,tr|H0YLE8|H0YLE8_HUMAN,tr|A0A0J9YXZ5|A0A0J9YXZ5_HUMAN" 3 1781.8709 1.18 37821 23279 2 1781.868261 891.9427 Ras GTPase-activating-like protein IQGAP1 OS=Homo sapiens OX=9606 GN=IQGAP1 PE=1 SV=1 4.03 3648.3 - 692948 - - - -1.4889 - 3.18 0.619 - 741.2 1 2 0 -0.0027 15 0 0 0 5.41E+06 4.60E+06 - - - 6.4563 1 221125_WJC_METTL3_EV_vs_WT_F03.23282.23282.2 5.56E-10 13/32 R.VFIWTC[160.03]DDASSNTWSPK.L "sp|P55735|SEC13_HUMAN,tr|A8MXL6|A8MXL6_HUMAN" 2 2012.8938 0.84 37824 23282 2 2012.893224 1007.4542 Protein SEC13 homolog OS=Homo sapiens OX=9606 GN=SEC13 PE=1 SV=3 4.21 3648.7 - 454363 - - - -0.3001 - 3.197 0.753 - 370.7 1 2 0 -0.0006 17 0 0 0 4.60E+06 5.46E+06 - - - 7.4598 1 221125_WJC_METTL3_EV_vs_WT_F03.23283.23283.2 4.43E-11 18/32 K.VTEGLVDVILYHQPDDK[136.11].K "sp|O43390|HNRPR_HUMAN,tr|B4DT28|B4DT28_HUMAN,tr|A0A6Q8PHG0|A0A6Q8PHG0_HUMAN,tr|A0A6Q8PH31|A0A6Q8PH31_HUMAN,tr|A0A6Q8PEX7|A0A6Q8PEX7_HUMAN" 5 1948.0033 2.19 37825 23283 2 1948.001184 975.0089 Heterogeneous nuclear ribonucleoprotein R OS=Homo sapiens OX=9606 GN=HNRNPR PE=1 SV=1 4.22 3648.9 - 402108 - - - -1.0903 - 3.573 0.668 - 1056.9 1 2 0 -0.0021 17 0 0 0 8.00E+06 3.66E+06 - - - 7.1049 0.9998 221125_WJC_METTL3_EV_vs_WT_F03.23287.23287.3 2.74E-05 13/60 K.SKGYAFIEFASFEDAK.E "sp|P19338|NUCL_HUMAN,tr|A0A7I2V506|A0A7I2V506_HUMAN,tr|A0A7I2V699|A0A7I2V699_HUMAN,tr|A0A7I2V2U7|A0A7I2V2U7_HUMAN,tr|A0A7I2V3F3|A0A7I2V3F3_HUMAN,tr|A0A7I2V428|A0A7I2V428_HUMAN,tr|A0A7I2V349|A0A7I2V349_HUMAN,tr|H7BY16|H7BY16_HUMAN,tr|A0A7I2V5M5|A0A7I2V5M5_HUMAN,tr|C9JLB1|C9JLB1_HUMAN" 10 1808.8621 0.99 37827 23287 3 1808.865361 603.9613 Nucleolin OS=Homo sapiens OX=9606 GN=NCL PE=1 SV=3 4.68 3649.3 - 3.23E+06 - - - 1.7934 - 2.893 0.525 - 314.9 1 2 1 0.0032 16 0 0 0 2.68E+07 2.70E+07 - - - 7.118 0.9922 221125_WJC_METTL3_EV_vs_WT_F03.23288.23288.2 1.06 15/24 S.QEILELLNTTTAK[136.11].E "sp|Q86U44|MTA70_HUMAN,tr|H0YFV6|H0YFV6_HUMAN" 2 1480.8228 0.05 37828 23288 2 1480.824179 741.4187 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 4.53 3649.4 - 2.42E+06 - - - 0.915 - 3.021 0.445 - 1126.8 1 1 0 0.0014 13 0 0 0 9.57E+05 1.99E+07 - - - 5.1649 1 221125_WJC_METTL3_EV_vs_WT_F03.23289.23289.3 1.08E-12 23/56 K.VAC[160.03]ITEQVLTLVNKR.L "sp|P04843|RPN1_HUMAN,tr|B7Z4L4|B7Z4L4_HUMAN" 2 1742.9713 1.21 37829 23289 3 1742.972199 581.9977 Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit 1 OS=Homo sapiens OX=9606 GN=RPN1 PE=1 SV=1 8.19 3649.4 - 2.11E+06 - - - 0.5215 - 3.592 0.644 - 943.3 1 2 0 0.0009 15 0 0 0 5.83E+07 4.80E+07 - - - 9.0563 1 221125_WJC_METTL3_EV_vs_WT_F03.23290.23290.3 9.78E-08 23/56 K.VAC[160.03]ITEQVLTLVNK[136.11]R[166.11].L "sp|P04843|RPN1_HUMAN,tr|B7Z4L4|B7Z4L4_HUMAN" 2 1760.9938 1.21 37830 23290 3 1760.993854 588.0052 Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit 1 OS=Homo sapiens OX=9606 GN=RPN1 PE=1 SV=1 8.19 3649.5 - 1.80E+06 - - - 0.0534 - 3.791 0.635 - 1037.4 1 2 0 0.0001 15 0 0 0 5.83E+07 4.80E+07 - - - 9.0969 1 221125_WJC_METTL3_EV_vs_WT_F03.23292.23292.2 4.74E-09 16/44 R.FSSGGAC[160.03]GLGGGYGGGFSSSSSF.G sp|P08779|K1C16_HUMAN 1 2088.8483 - 37832 23292 2 2088.848972 1045.4314 "Keratin, type I cytoskeletal 16 OS=Homo sapiens OX=9606 GN=KRT16 PE=1 SV=4" 5.52 3649.7 - 1.42E+06 - - - 0.3054 - 3.866 0.633 - 461.2 1 1 0 0.0006 23 0 0 0 - - - - - 7.0406 1 221125_WJC_METTL3_EV_vs_WT_F03.23294.23294.2 6.99E-09 16/32 R.DAEDAMDAMDGAVLDGR.E "sp|Q01130|SRSF2_HUMAN,tr|J3KP15|J3KP15_HUMAN,tr|J3QL05|J3QL05_HUMAN" 3 1750.7138 0.56 37834 23294 2 1750.707815 876.3642 Serine\arginine-rich splicing factor 2 OS=Homo sapiens OX=9606 GN=SRSF2 PE=1 SV=4 3.61 3650 - 1.02E+06 - - - -3.4266 - 3.659 0.738 - 832.2 1 2 0 -0.006 17 0 0 0 4.07E+06 7.21E+06 - - - 7.6792 1 221125_WJC_METTL3_EV_vs_WT_F03.23295.23295.3 1.71E-05 16/48 K.K[136.11]QPALDVLYDVMK[136.11].S sp|Q14152|EIF3A_HUMAN 1 1534.84 1.16 37835 23295 3 1534.841312 512.6206 Eukaryotic translation initiation factor 3 subunit A OS=Homo sapiens OX=9606 GN=EIF3A PE=1 SV=1 5.96 3650.1 - 934349 - - - 0.8542 - 2.792 0.571 - 446.4 1 2 0 0.0013 13 0 0 0 1.77E+07 1.52E+07 - - - 7.6896 1 221125_WJC_METTL3_EV_vs_WT_F03.23296.23296.2 9.18E-07 20/32 R.DAEDAMDAMDGAVLDGR[166.11].E "sp|Q01130|SRSF2_HUMAN,tr|J3KP15|J3KP15_HUMAN,tr|J3QL05|J3QL05_HUMAN" 3 1760.7221 0.56 37836 23296 2 1760.718595 881.3683 Serine\arginine-rich splicing factor 2 OS=Homo sapiens OX=9606 GN=SRSF2 PE=1 SV=4 3.61 3650.2 - 886296 - - - -1.9816 - 3.967 0.714 - 1457.2 1 2 0 -0.0035 17 0 0 0 4.07E+06 7.21E+06 - - - 7.7014 0.9998 221125_WJC_METTL3_EV_vs_WT_F03.23297.23297.3 0.000984 14/48 K.VISDK[136.11]DLELLLDR[166.11].S "sp|Q9NRZ9|HELLS_HUMAN,tr|Q9NW36|Q9NW36_HUMAN,tr|A0A087WSW7|A0A087WSW7_HUMAN,tr|A0A0B4J1V9|A0A0B4J1V9_HUMAN,tr|F6XU50|F6XU50_HUMAN" 5 1545.8733 0.84 37837 23297 3 1545.87332 516.2984 Lymphoid-specific helicase OS=Homo sapiens OX=9606 GN=HELLS PE=1 SV=1 4.23 3650.4 - 875598 - - - 0.0168 - 2.924 0.429 - 333.9 1 2 1 0 13 0 0 0 4.23E+06 5.02E+06 - - - 6.232 0.9893 221125_WJC_METTL3_EV_vs_WT_F03.23299.23299.4 2.48E-05 13/96 R.SPSELFAQHIVTIVHHV.K "sp|Q9Y2W1|TR150_HUMAN,tr|A0A3B3ITZ9|A0A3B3ITZ9_HUMAN" 2 1913.0159 - 37839 23299 4 1913.015799 479.2613 Thyroid hormone receptor-associated protein 3 OS=Homo sapiens OX=9606 GN=THRAP3 PE=1 SV=2 6.2 3650.6 - 574038 - - - -0.0695 - 2.485 0.427 - 127.4 1 1 0 -0.0001 17 0 0 0 - - - - - 3.2586 0.9818 221125_WJC_METTL3_EV_vs_WT_F03.23301.23301.3 0.000872 Dec-48 S.QEILELLNTTTAK[136.11].E "sp|Q86U44|MTA70_HUMAN,tr|H0YFV6|H0YFV6_HUMAN" 2 1480.8228 0.04 37841 23301 3 1480.822388 494.6149 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 4.53 3650.8 - 506228 - - - -0.2944 - 2.442 0.333 - 267.1 1 1 0 -0.0004 13 0 0 0 8.72E+04 2.33E+06 - - - 4.6732 1 221125_WJC_METTL3_EV_vs_WT_F03.23303.23303.2 9.01E-09 16/32 R.KLFIGGLSFETTEESLR.N "sp|P22626|ROA2_HUMAN,tr|A0A7I2YQN4|A0A7I2YQN4_HUMAN,tr|A0A7I2V4N0|A0A7I2V4N0_HUMAN,tr|A0A7I2V4N1|A0A7I2V4N1_HUMAN,tr|A0A7I2V4I6|A0A7I2V4I6_HUMAN,tr|A0A087WUI2|A0A087WUI2_HUMAN,tr|A0A7I2V4S4|A0A7I2V4S4_HUMAN,tr|A0A7I2V323|A0A7I2V323_HUMAN,tr|A0A7I2V3P1|A0A7I2V3P1_HUMAN,tr|A0A7I2V3P7|A0A7I2V3P7_HUMAN" 10 1926.0098 2.75 37843 23303 2 1926.013513 964.0122 Heterogeneous nuclear ribonucleoproteins A2\B1 OS=Homo sapiens OX=9606 GN=HNRNPA2B1 PE=1 SV=2 4.79 3651.1 - 455388 - - - 1.905 - 3.327 0.639 - 471.5 1 2 0 0.0037 17 0 0 0 3.27E+06 1.19E+06 - - - 6.7148 1 221125_WJC_METTL3_EV_vs_WT_F03.23311.23311.3 2.48E-11 26/84 R.R[166.11]GPFELEAFYSDPQGVPYPEAK[136.11].L "sp|Q92598|HS105_HUMAN,tr|A0A0A0MSM0|A0A0A0MSM0_HUMAN" 2 2514.2186 0.13 37849 23311 3 2514.221459 839.0801 Heat shock protein 105 kDa OS=Homo sapiens OX=9606 GN=HSPH1 PE=1 SV=1 4.41 3652.1 - 2.28E+06 - - - 1.1328 - 3.369 0.669 - 741.3 1 2 0 0.0028 22 0 0 0 1.34E+07 1.04E+08 - - - 8.8776 1 221125_WJC_METTL3_EV_vs_WT_F03.23316.23316.4 1.55E-12 23/114 R.K[136.11]VDPMAIVVFHQADIGEYVR[166.11].H sp|Q9Y221|NIP7_HUMAN 1 2304.2055 2.23 37854 23316 4 2304.204141 577.0587 60S ribosome subunit biogenesis protein NIP7 homolog OS=Homo sapiens OX=9606 GN=NIP7 PE=1 SV=1 5.38 3652.4 - 1.37E+06 - - - -0.6089 - 4.157 0.552 - 400.4 1 2 0 -0.0014 20 0 0 0 2.14E+07 9.61E+06 - - - 4.5066 0.9771 221125_WJC_METTL3_EV_vs_WT_F03.23317.23317.3 0.0329 Aug-60 K.VLSLPKPTIILSAYQR.K "sp|Q99567|NUP88_HUMAN,tr|J3KMX1|J3KMX1_HUMAN" 2 1798.0717 1.76 37855 23317 3 1798.069559 600.3645 Nuclear pore complex protein Nup88 OS=Homo sapiens OX=9606 GN=NUP88 PE=1 SV=2 9.99 3652.5 - 2.04E+06 - - - -1.1662 - 1.679 0.146 - 57.1 2 2 0 -0.0021 16 0 0 0 2.56E+07 1.45E+07 - - - 1.3575 1 221125_WJC_METTL3_EV_vs_WT_F03.23320.23320.2 1.09E-12 15/32 R.YTSEDNASFQEIMEVAK.E "sp|Q96DF8|ESS2_HUMAN,tr|F8WEF8|F8WEF8_HUMAN" 2 1960.8724 1.74 37858 23320 2 1960.865355 981.4435 Splicing factor ESS-2 homolog OS=Homo sapiens OX=9606 GN=ESS2 PE=1 SV=1 4 3652.9 - 686339 - - - -3.6045 - 3.363 0.654 - 663.1 1 2 0 -0.0071 17 0 0 0 2.40E+07 1.38E+07 - - - 6.851 0.9998 221125_WJC_METTL3_EV_vs_WT_F03.23321.23321.3 0.0341 15/56 K.KASVVTLPVYLNFTR.A "sp|Q14204|DYHC1_HUMAN,tr|A0A2R8Y706|A0A2R8Y706_HUMAN" 2 1706.9719 0.78 37859 23321 3 1706.9724 569.9979 Cytoplasmic dynein 1 heavy chain 1 OS=Homo sapiens OX=9606 GN=DYNC1H1 PE=1 SV=5 9.99 3653 - 589865 - - - 0.2683 - 2.466 0.332 - 294.8 1 2 0 0.0005 15 0 0 0 3.60E+06 4.64E+06 - - - 4.5966 1 221125_WJC_METTL3_EV_vs_WT_F03.23322.23322.3 0.000135 Dec-44 K.TGELNQLLNAVK.S "sp|Q15643|TRIPB_HUMAN,tr|H0YJ97|H0YJ97_HUMAN" 2 1298.7194 2.49 37860 23322 3 1298.718719 433.9137 Thyroid receptor-interacting protein 11 OS=Homo sapiens OX=9606 GN=TRIP11 PE=1 SV=3 5.66 3653.1 - 588534 - - - -0.5359 - 2.24 0.467 - 251.2 1 2 0 -0.0007 12 0 0 0 2.93E+06 1.18E+06 - - - 5.9818 1 221125_WJC_METTL3_EV_vs_WT_F03.23325.23325.3 2.60E-11 22/96 R.TPVPSTVQANTFEFADAEEDDEVKV.- sp|Q00587|BORG5_HUMAN 1 2737.2607 1.35 37861 23325 3 2737.26039 913.4275 Cdc42 effector protein 1 OS=Homo sapiens OX=9606 GN=CDC42EP1 PE=1 SV=1 3.66 3653.5 - 4.10E+06 - - - -0.0954 - 4.986 0.703 - 569.1 1 2 0 -0.0003 25 0 0 0 4.43E+07 3.28E+07 - - - 10.074 1 221125_WJC_METTL3_EV_vs_WT_F03.23329.23329.3 4.65E-10 15/76 R.VTFALPDDAETEDTGVLNVK.K "sp|O00566|MPP10_HUMAN,tr|U3KQ48|U3KQ48_HUMAN" 2 2133.0477 0.51 37865 23329 3 2133.052337 712.0232 U3 small nucleolar ribonucleoprotein protein MPP10 OS=Homo sapiens OX=9606 GN=MPHOSPH10 PE=1 SV=2 3.77 3653.8 - 2.50E+06 - - - 2.1528 - 3.298 0.6 - 302.6 1 2 0 0.0046 20 0 0 0 2.52E+07 4.95E+07 - - - 8.1231 1 221125_WJC_METTL3_EV_vs_WT_F03.23332.23332.3 0.000894 15/44 R.KGFLSGLLDNVK.Q "sp|O43615|TIM44_HUMAN,tr|M0R301|M0R301_HUMAN,tr|M0R124|M0R124_HUMAN,tr|M0QXU7|M0QXU7_HUMAN" 4 1289.7343 1.08 37868 23332 3 1289.733756 430.9187 Mitochondrial import inner membrane translocase subunit TIM44 OS=Homo sapiens OX=9606 GN=TIMM44 PE=1 SV=2 8.59 3654.1 - 1.47E+06 - - - -0.4505 - 2.925 0.402 - 482.7 1 2 0 -0.0006 12 0 0 0 4.23E+07 3.92E+07 - - - 5.9968 0.9968 221125_WJC_METTL3_EV_vs_WT_F03.23335.23335.2 0.013 26-Jun K.ETLTFPPEVPISEK[136.11].A sp|Q15208|STK38_HUMAN 1 1593.8381 3.74 37871 23335 2 1593.835619 797.9263 Serine\threonine-protein kinase 38 OS=Homo sapiens OX=9606 GN=STK38 PE=1 SV=1 4.25 3654.4 - 476380 - - - -1.5817 - 1.458 0.248 - 89 1 2 0 -0.0025 14 0 0 0 3.77E+07 1.01E+07 - - - 1.8182 0.9949 221125_WJC_METTL3_EV_vs_WT_F03.23336.23336.2 1.10E-05 30-Dec K.VIAALLQTMEDQGNQR[166.11].V "sp|O00410|IPO5_HUMAN,tr|H0Y8C6|H0Y8C6_HUMAN" 2 1795.9126 1.05 37872 23336 2 1795.921875 898.9636 Importin-5 OS=Homo sapiens OX=9606 GN=IPO5 PE=1 SV=4 4.37 3654.6 - 468548 - - - 5.1628 - 1.843 0.453 - 97.9 1 2 0 0.0093 16 0 0 0 4.67E+06 4.45E+06 - - - 3.8871 1 221125_WJC_METTL3_EV_vs_WT_F03.23342.23342.3 1.14E-06 19/68 K.TLLPVPSFEDVSIPEKPK.L sp|Q9NX20|RM16_HUMAN 1 1995.0928 1.1 37876 23342 3 1995.095061 666.0382 "39S ribosomal protein L16, mitochondrial OS=Homo sapiens OX=9606 GN=MRPL16 PE=1 SV=1" 4.68 3655.3 - 6.07E+06 - - - 1.1107 - 3.27 0.574 - 325.1 1 2 0 0.0022 18 0 0 0 2.10E+08 1.90E+08 - - - 7.8892 1 221125_WJC_METTL3_EV_vs_WT_F03.23343.23343.3 1.33E-09 16/68 K.TLLPVPSFEDVSIPEK[136.11]PK[136.11].L sp|Q9NX20|RM16_HUMAN 1 2011.1212 1.1 37877 23343 3 2011.123562 671.381 "39S ribosomal protein L16, mitochondrial OS=Homo sapiens OX=9606 GN=MRPL16 PE=1 SV=1" 4.68 3655.3 - 6.20E+06 - - - 1.1521 - 2.879 0.614 - 209.4 1 2 0 0.0023 18 0 0 0 2.10E+08 1.90E+08 - - - 8.018 1 221125_WJC_METTL3_EV_vs_WT_F03.23344.23344.3 5.54E-07 20/68 K.ISSIQSIVPALEIANAHR.K "sp|P10809|CH60_HUMAN,tr|A0A7I2V2X6|A0A7I2V2X6_HUMAN,tr|A0A7I2YQK6|A0A7I2YQK6_HUMAN,tr|A0A7I2V599|A0A7I2V599_HUMAN,tr|A0A7I2YQ71|A0A7I2YQ71_HUMAN,tr|A0A7I2V5M1|A0A7I2V5M1_HUMAN,tr|A0A7I2V5K3|A0A7I2V5K3_HUMAN,tr|A0A7I2V369|A0A7I2V369_HUMAN" 8 1918.0636 1.33 37878 23344 3 1918.066883 640.3618 "60 kDa heat shock protein, mitochondrial OS=Homo sapiens OX=9606 GN=HSPD1 PE=1 SV=2" 6.75 3655.4 - 4.19E+06 - - - 1.7064 - 3.427 0.533 - 437.5 1 2 0 0.0033 18 0 0 0 2.01E+10 1.51E+10 - - - 7.5485 1 221125_WJC_METTL3_EV_vs_WT_F03.23345.23345.3 3.03E-12 27/80 R.NVVFVDMGHSAYQVSVC[160.03]AFNR[166.11].G "sp|P34932|HSP74_HUMAN,tr|A0A087WTS8|A0A087WTS8_HUMAN,tr|A0A087WYC1|A0A087WYC1_HUMAN" 3 2409.1233 0.11 37879 23345 3 2409.125007 804.0484 Heat shock 70 kDa protein 4 OS=Homo sapiens OX=9606 GN=HSPA4 PE=1 SV=4 6.73 3655.5 - 2.67E+06 - - - 0.6915 - 4.548 0.712 - 656.9 1 2 0 0.0017 21 0 0 0 1.51E+06 1.35E+07 - - - 10.109 0.9997 221125_WJC_METTL3_EV_vs_WT_F03.23347.23347.2 0.000442 13/24 K.GISLNPEQWSQLK.E sp|P53999|TCP4_HUMAN 1 1498.778 0.19 37881 23347 2 1498.78163 750.3963 Activated RNA polymerase II transcriptional coactivator p15 OS=Homo sapiens OX=9606 GN=SUB1 PE=1 SV=3 6 3655.6 - 2.15E+06 - - - 2.4266 - 2.688 0.496 - 473.2 1 2 0 0.0036 13 0 0 0 1.90E+07 1.02E+08 - - - 5.2411 1 221125_WJC_METTL3_EV_vs_WT_F03.23349.23349.2 1.49E-12 18/38 R.VTFALPDDAETEDTGVLNVK.K "sp|O00566|MPP10_HUMAN,tr|U3KQ48|U3KQ48_HUMAN" 2 2133.0477 5.07 37883 23349 2 2133.055211 1067.5311 U3 small nucleolar ribonucleoprotein protein MPP10 OS=Homo sapiens OX=9606 GN=MPHOSPH10 PE=1 SV=2 3.77 3655.8 - 1.69E+06 - - - 3.5002 - 3.568 0.711 - 610.6 1 2 0 0.0075 20 0 0 0 1.45E+07 2.86E+06 - - - 7.4174 1 221125_WJC_METTL3_EV_vs_WT_F03.23350.23350.3 3.35E-22 29/96 R.TPYTMGYGESMYYNDAYGALDYYK[136.11]R[166.11].Y sp|Q9BQ04|RBM4B_HUMAN 1 3009.2956 1.62 37884 23350 3 3009.29042 1004.1058 RNA-binding protein 4B OS=Homo sapiens OX=9606 GN=RBM4B PE=1 SV=1 4.56 3656 - 1.69E+06 - - - -1.727 - 4.682 0.807 - 685.6 1 2 0 -0.0052 25 0 0 0 1.09E+07 6.71E+06 - - - 11.0874 1 221125_WJC_METTL3_EV_vs_WT_F03.23351.23351.3 8.94E-06 13/48 R.R[166.11]LTLEDLEDSWDR[166.11].G "sp|Q6P2Q9|PRP8_HUMAN,tr|I3L3Z8|I3L3Z8_HUMAN" 2 1666.8066 1.49 37885 23351 3 1666.806682 556.6095 Pre-mRNA-processing-splicing factor 8 OS=Homo sapiens OX=9606 GN=PRPF8 PE=1 SV=2 4.11 3656 - 1.40E+06 - - - 0.0768 - 2.796 0.484 - 207 1 2 0 0.0001 13 0 0 0 1.70E+07 1.14E+07 - - - 6.7238 1 221125_WJC_METTL3_EV_vs_WT_F03.23356.23356.3 2.20E-07 20/64 K.LLYDLADQLHAAVGASR[166.11].A "sp|P13804|ETFA_HUMAN,tr|H0YK49|H0YK49_HUMAN,tr|H0YL12|H0YL12_HUMAN,tr|H0YNX6|H0YNX6_HUMAN" 4 1821.9613 1.71 37888 23356 3 1821.961188 608.3277 "Electron transfer flavoprotein subunit alpha, mitochondrial OS=Homo sapiens OX=9606 GN=ETFA PE=1 SV=1" 5.21 3656.6 - 8.75E+06 - - - -0.0434 - 3.51 0.614 - 479.1 1 2 0 -0.0001 17 0 0 0 1.15E+08 6.71E+07 - - - 8.5575 1 221125_WJC_METTL3_EV_vs_WT_F03.23357.23357.3 7.46E-07 23/84 R.RGPFELEAFYSDPQGVPYPEAK.L "sp|Q92598|HS105_HUMAN,tr|A0A0A0MSM0|A0A0A0MSM0_HUMAN" 2 2496.1961 0.13 37889 23357 3 2496.198026 833.0727 Heat shock protein 105 kDa OS=Homo sapiens OX=9606 GN=HSPH1 PE=1 SV=1 4.41 3656.7 - 1.76E+06 - - - 0.7551 - 3.575 0.623 - 466.9 1 2 0 0.0019 22 0 0 0 1.32E+07 1.04E+08 - - - 8.5057 1 221125_WJC_METTL3_EV_vs_WT_F03.23358.23358.2 8.87E-07 26-Dec K.LISWYDNEFGYSNR[166.11].V "sp|P04406|G3P_HUMAN,tr|E7EUT5|E7EUT5_HUMAN" 2 1772.8034 1.14 37890 23358 2 1772.80106 887.409 Glyceraldehyde-3-phosphate dehydrogenase OS=Homo sapiens OX=9606 GN=GAPDH PE=1 SV=3 4.37 3656.9 - 815220 - - - -1.303 - 2.243 0.64 - 373.1 1 2 0 -0.0023 14 0 0 0 2.15E+08 1.89E+08 - - - 5.7945 1 221125_WJC_METTL3_EV_vs_WT_F03.23360.23360.2 5.33E-14 23/32 K.LLYDLADQLHAAVGASR.A "sp|P13804|ETFA_HUMAN,tr|H0YK49|H0YK49_HUMAN,tr|H0YL12|H0YL12_HUMAN,tr|H0YNX6|H0YNX6_HUMAN" 4 1811.953 2.69 37892 23360 2 1811.954527 906.9838 "Electron transfer flavoprotein subunit alpha, mitochondrial OS=Homo sapiens OX=9606 GN=ETFA PE=1 SV=1" 5.21 3657.1 - 754626 - - - 0.8444 - 4.176 0.659 - 2043.8 1 2 0 0.0015 17 0 0 0 4.15E+06 1.54E+06 - - - 7.422 0.9658 221125_WJC_METTL3_EV_vs_WT_F03.23361.23361.2 0.00014 26-Sep R.YIQPWESEFIDSQR.V sp|Q6P2Q9|PRP8_HUMAN 1 1796.837 -1 37893 23361 2 1796.82293 899.4258 Pre-mRNA-processing-splicing factor 8 OS=Homo sapiens OX=9606 GN=PRPF8 PE=1 SV=2 4.14 3657.2 - 447921 - - - -7.8104 - 1.9 0.399 - 163 1 2 0 -0.014 14 0 0 0 0.00E+00 0.00E+00 - - - 3.5943 1 221125_WJC_METTL3_EV_vs_WT_F03.23363.23363.2 5.70E-11 16/38 R.SLSSAINASTGNYLLESVNK.L "sp|P05120|PAI2_HUMAN,tr|E7EPJ9|E7EPJ9_HUMAN,tr|E7ERB5|E7ERB5_HUMAN" 3 2067.0484 -1 37895 23363 2 2067.048822 1034.5315 Plasminogen activator inhibitor 2 OS=Homo sapiens OX=9606 GN=SERPINB2 PE=1 SV=2 5.72 3657.5 - 380294 - - - 0.1974 - 3.434 0.677 - 686.9 1 2 0 0.0004 20 0 0 0 0.00E+00 0.00E+00 - - - 7.0744 1 221125_WJC_METTL3_EV_vs_WT_F03.23364.23364.3 7.12E-09 14/44 R.TC[160.03]LHAILNILEK[136.11].G "sp|Q92621|NU205_HUMAN,tr|U3KQ97|U3KQ97_HUMAN,tr|U3KQ47|U3KQ47_HUMAN" 3 1431.7999 1.34 37896 23364 3 1431.801195 478.2739 Nuclear pore complex protein Nup205 OS=Homo sapiens OX=9606 GN=NUP205 PE=1 SV=3 6.41 3657.6 - 298371 - - - 0.8898 - 2.971 0.538 - 275.5 1 2 0 0.0013 12 0 0 0 2.17E+06 1.62E+06 - - - 7.5561 1 221125_WJC_METTL3_EV_vs_WT_F03.23367.23367.3 8.66E-11 22/68 K.ISSIQSIVPALEIANAHR[166.11].K "sp|P10809|CH60_HUMAN,tr|A0A7I2V2X6|A0A7I2V2X6_HUMAN,tr|A0A7I2YQK6|A0A7I2YQK6_HUMAN,tr|A0A7I2V599|A0A7I2V599_HUMAN,tr|A0A7I2YQ71|A0A7I2YQ71_HUMAN,tr|A0A7I2V5M1|A0A7I2V5M1_HUMAN,tr|A0A7I2V5K3|A0A7I2V5K3_HUMAN,tr|A0A7I2V369|A0A7I2V369_HUMAN" 8 1928.0719 1.33 37897 23367 3 1928.073095 643.6979 "60 kDa heat shock protein, mitochondrial OS=Homo sapiens OX=9606 GN=HSPD1 PE=1 SV=2" 6.75 3658 - 9.74E+06 - - - 0.6302 - 3.542 0.631 - 540.4 1 2 0 0.0012 18 0 0 0 2.01E+10 1.51E+10 - - - 8.7239 0.9999 221125_WJC_METTL3_EV_vs_WT_F03.23368.23368.2 0.0309 14/22 R.GVVQELQQAISK.L "sp|P29692|EF1D_HUMAN,tr|E9PI39|E9PI39_HUMAN,tr|E9PMW7|E9PMW7_HUMAN,tr|E9PQ49|E9PQ49_HUMAN,tr|A0A087X1X7|A0A087X1X7_HUMAN,tr|E9PL12|E9PL12_HUMAN,tr|H0YCK7|H0YCK7_HUMAN,tr|E9PIZ1|E9PIZ1_HUMAN,tr|E9PN91|E9PN91_HUMAN,tr|E9PPR1|E9PPR1_HUMAN,tr|E9PRY8|E9PRY8_HUMAN,tr|E9PK01|E9PK01_HUMAN,tr|E9PL71|E9PL71_HUMAN" 13 1298.7194 1.41 37898 23368 2 1298.72014 650.367 Elongation factor 1-delta OS=Homo sapiens OX=9606 GN=EEF1D PE=1 SV=5 6 3658.1 - 8.21E+06 - - - 0.5582 - 2.727 0.42 - 898.9 1 2 0 0.0007 12 0 0 0 2.49E+08 1.77E+08 - - - 4.7825 0.9998 221125_WJC_METTL3_EV_vs_WT_F03.23371.23371.3 0.306 16/60 R.MIAGQVLDINLAAEPK[136.11].V "sp|P07910|HNRPC_HUMAN,tr|G3V251|G3V251_HUMAN,tr|B4DY08|B4DY08_HUMAN,tr|G3V575|G3V575_HUMAN,tr|B4DSU6|B4DSU6_HUMAN,tr|G3V3K6|G3V3K6_HUMAN,tr|B2R5W2|B2R5W2_HUMAN,tr|G3V4C1|G3V4C1_HUMAN,tr|G3V576|G3V576_HUMAN,tr|G3V5X6|G3V5X6_HUMAN,tr|G3V4W0|G3V4W0_HUMAN,tr|G3V555|G3V555_HUMAN,tr|G3V2Q1|G3V2Q1_HUMAN" 13 1689.9215 1.5 37901 23371 3 1689.926091 564.3144 Heterogeneous nuclear ribonucleoproteins C1\C2 OS=Homo sapiens OX=9606 GN=HNRNPC PE=1 SV=4 4.37 3658.4 - 879756 - - - 2.7208 - 2.932 0.392 - 270.8 1 2 0 0.0046 16 0 0 0 1.55E+07 1.03E+07 - - - 5.6692 1 221125_WJC_METTL3_EV_vs_WT_F03.23380.23380.2 4.58E-09 14/26 K.LISWYDNEFGYSNR.V "sp|P04406|G3P_HUMAN,tr|E7EUT5|E7EUT5_HUMAN" 2 1762.7951 1.14 37908 23380 2 1762.794844 882.4048 Glyceraldehyde-3-phosphate dehydrogenase OS=Homo sapiens OX=9606 GN=GAPDH PE=1 SV=3 4.37 3659.6 - 1.10E+07 - - - -0.1452 - 2.827 0.703 - 786.9 1 2 0 -0.0003 14 0 0 0 2.15E+08 1.89E+08 - - - 6.8411 0.9997 221125_WJC_METTL3_EV_vs_WT_F03.23381.23381.2 6.37E-05 24-Dec K.GISLNPEQWSQLK[136.11].E sp|P53999|TCP4_HUMAN 1 1506.7922 0.19 37909 23381 2 1506.795602 754.4034 Activated RNA polymerase II transcriptional coactivator p15 OS=Homo sapiens OX=9606 GN=SUB1 PE=1 SV=3 6 3659.6 - 3.45E+06 - - - 2.2624 - 2.632 0.482 - 401.4 1 2 0 0.0034 13 0 0 0 1.90E+07 1.02E+08 - - - 5.0837 0.9998 221125_WJC_METTL3_EV_vs_WT_F03.23382.23382.3 0.00201 20/76 R.AGAASLDVIQEVEYVK[136.11]EEAK[136.11].M sp|Q9UJV9|DDX41_HUMAN 1 2164.1234 1.17 37910 23382 3 2164.127406 722.3818 Probable ATP-dependent RNA helicase DDX41 OS=Homo sapiens OX=9606 GN=DDX41 PE=1 SV=2 4.25 3659.7 - 2.55E+06 - - - 1.8372 - 3.796 0.452 - 375.9 1 2 1 0.004 20 0 0 0 7.55E+07 6.44E+07 - - - 6.8144 0.9952 221125_WJC_METTL3_EV_vs_WT_F03.23385.23385.3 5.18E-09 25/92 Y.ADQPIDADVTVIGSGPGGYVAAIK[136.11].A "sp|P09622|DLDH_HUMAN,tr|E9PEX6|E9PEX6_HUMAN,tr|F8WDM5|F8WDM5_HUMAN,tr|F2Z2E3|F2Z2E3_HUMAN,tr|A0A1W2PR83|A0A1W2PR83_HUMAN" 5 2321.1994 3 37913 23385 3 2321.206982 774.7404 "Dihydrolipoyl dehydrogenase, mitochondrial OS=Homo sapiens OX=9606 GN=DLD PE=1 SV=2" 3.93 3660.1 - 1.46E+06 - - - 3.2483 - 4.368 0.568 - 894.3 1 1 0 0.0075 24 0 0 0 3.31E+07 1.10E+07 - - - 8.2948 1 221125_WJC_METTL3_EV_vs_WT_F03.23386.23386.3 3.50E-07 22/52 Y.TSGLETLLNIPIKR.T sp|P15924|DESP_HUMAN 1 1553.9141 999 37914 23386 3 1553.915264 518.9786 Desmoplakin OS=Homo sapiens OX=9606 GN=DSP PE=1 SV=3 8.41 3660.2 - 1.35E+06 - - - 0.7536 - 3.216 0.619 - 727.2 1 1 0 0.0012 14 0 0 0 1.03E+07 0.00E+00 - - - 8.5453 0.9999 221125_WJC_METTL3_EV_vs_WT_F03.23387.23387.3 3.49E-07 14/72 K.TQPYDVYDQVEFDVPVGSR[166.11].G "sp|O75306|NDUS2_HUMAN,tr|A0A7I2V4X8|A0A7I2V4X8_HUMAN,tr|A0A7I2V4G5|A0A7I2V4G5_HUMAN,tr|A0A7I2YQG7|A0A7I2YQG7_HUMAN,tr|A0A7I2V596|A0A7I2V596_HUMAN,tr|A0A7I2V5G4|A0A7I2V5G4_HUMAN,tr|A0A7I2V410|A0A7I2V410_HUMAN,tr|A0A7I2V630|A0A7I2V630_HUMAN,tr|A0A7I2V2B9|A0A7I2V2B9_HUMAN,tr|A0A7I2YQD8|A0A7I2YQD8_HUMAN,tr|A0A7I2V3J6|A0A7I2V3J6_HUMAN,tr|A0A7I2V5E2|A0A7I2V5E2_HUMAN,tr|A0A7I2V4W5|A0A7I2V4W5_HUMAN" 13 2223.0359 1.65 37915 23387 3 2223.042218 742.0193 "NADH dehydrogenase [ubiquinone] iron-sulfur protein 2, mitochondrial OS=Homo sapiens OX=9606 GN=NDUFS2 PE=1 SV=2" 3.84 3660.3 - 1.30E+06 - - - 2.8205 - 2.657 0.482 - 203.7 1 2 0 0.0063 19 0 0 0 1.28E+07 7.75E+06 - - - 6.3129 1 221125_WJC_METTL3_EV_vs_WT_F03.23396.23396.3 1.91E-06 14/68 R.LLTETEDWLYEEGEDQAK[136.11].Q "sp|Q92598|HS105_HUMAN,tr|A0A0A0MSM0|A0A0A0MSM0_HUMAN" 2 2175.9939 0.07 37922 23396 3 2175.997701 726.3386 Heat shock protein 105 kDa OS=Homo sapiens OX=9606 GN=HSPH1 PE=1 SV=1 3.71 3661.4 - 1.58E+07 - - - 1.7353 - 2.605 0.556 - 262 1 2 0 0.0038 18 0 0 0 8.68E+06 1.26E+08 - - - 7.1219 0.9999 221125_WJC_METTL3_EV_vs_WT_F03.23397.23397.3 8.52E-11 20/76 R.AGAASLDVIQEVEYVKEEAK.M sp|Q9UJV9|DDX41_HUMAN 1 2148.095 1.13 37923 23397 3 2148.095867 717.039 Probable ATP-dependent RNA helicase DDX41 OS=Homo sapiens OX=9606 GN=DDX41 PE=1 SV=2 4.25 3661.4 - 7.66E+06 - - - 0.3896 - 4.081 0.476 - 429 1 2 1 0.0008 20 0 0 0 7.82E+07 6.93E+07 - - - 7.2585 0.9999 221125_WJC_METTL3_EV_vs_WT_F03.23398.23398.2 0.00481 14/22 K.DAGVIAGLNVLR[166.11].L "sp|P0DMV8|HS71A_HUMAN,sp|P34931|HS71L_HUMAN,sp|P0DMV9|HS71B_HUMAN,tr|Q53FA3|Q53FA3_HUMAN,tr|A0A0G2JIW1|A0A0G2JIW1_HUMAN" 5 1206.696 0.13 37924 23398 2 1206.696547 604.3553 Heat shock 70 kDa protein 1A OS=Homo sapiens OX=9606 GN=HSPA1A PE=1 SV=1 5.84 3661.5 - 9.67E+06 - - - 0.4608 - 2.803 0.427 - 769.6 1 2 0 0.0006 12 0 0 0 1.39E+07 1.07E+08 - - - 4.9066 0.9999 221125_WJC_METTL3_EV_vs_WT_F03.23399.23399.3 0.0137 Nov-52 K.LISWYDNEFGYSNR[166.11].V "sp|P04406|G3P_HUMAN,tr|E7EUT5|E7EUT5_HUMAN" 2 1772.8034 1.75 37925 23399 3 1772.802388 591.9417 Glyceraldehyde-3-phosphate dehydrogenase OS=Homo sapiens OX=9606 GN=GAPDH PE=1 SV=3 4.37 3661.5 - 8.72E+06 - - - -0.5539 - 1.893 0.45 - 150 1 2 0 -0.001 14 0 0 0 1.54E+08 8.76E+07 - - - 5.2527 1 221125_WJC_METTL3_EV_vs_WT_F03.23400.23400.3 1.86E-05 Oct-52 K.LISWYDNEFGYSNR.V "sp|P04406|G3P_HUMAN,tr|E7EUT5|E7EUT5_HUMAN" 2 1762.7951 1.75 37926 23400 3 1762.795447 588.6056 Glyceraldehyde-3-phosphate dehydrogenase OS=Homo sapiens OX=9606 GN=GAPDH PE=1 SV=3 4.37 3661.5 - 7.28E+06 - - - 0.1968 - 2.278 0.504 - 121.3 1 2 0 0.0003 14 0 0 0 1.54E+08 8.76E+07 - - - 6.3469 0.984 221125_WJC_METTL3_EV_vs_WT_F03.23402.23402.3 0.000164 Dec-76 K.IELFGR[166.11]PHNVQPNWITLGNQ.L sp|Q86U44|MTA70_HUMAN 1 2342.2159 0.02 37928 23402 3 2342.212945 781.7459 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 6.75 3661.6 - 4.27E+06 - - - -1.2697 - 2.629 0.361 - 143.6 1 1 0 -0.003 20 0 0 0 5.49E+06 2.52E+08 - - - 4.909 1 221125_WJC_METTL3_EV_vs_WT_F03.23403.23403.2 3.16E-10 18/28 R.ETNGLLQEELEGLQR.K sp|Q9Y6D9|MD1L1_HUMAN 1 1727.869 1.99 37929 23403 2 1727.869918 864.9418 Mitotic spindle assembly checkpoint protein MAD1 OS=Homo sapiens OX=9606 GN=MAD1L1 PE=1 SV=2 4.09 3661.8 - 2.19E+06 - - - 0.5353 - 3.245 0.653 - 1217.4 1 2 0 0.0009 15 0 0 0 2.86E+07 1.44E+07 - - - 6.7578 1 221125_WJC_METTL3_EV_vs_WT_F03.23404.23404.2 1.52E-12 15/30 K.GNENANGAPAITLLIR[166.11].E sp|Q9Y5B9|SP16H_HUMAN 1 1632.8823 1.07 37930 23404 2 1632.881619 817.4484 FACT complex subunit SPT16 OS=Homo sapiens OX=9606 GN=SUPT16H PE=1 SV=1 6 3661.9 - 2.07E+06 - - - -0.4103 - 3.314 0.612 - 418 1 2 0 -0.0007 16 0 0 0 2.44E+07 2.29E+07 - - - 6.5067 1 221125_WJC_METTL3_EV_vs_WT_F03.23412.23412.3 0.000319 13/48 R.DITLFHAMDTLQR[166.11].N sp|O94776|MTA2_HUMAN 1 1569.7849 1.12 37938 23412 3 1569.784323 524.2689 Metastasis-associated protein MTA2 OS=Homo sapiens OX=9606 GN=MTA2 PE=1 SV=1 5.21 3662.8 - 771815 - - - -0.3567 - 2.441 0.513 - 156.6 1 2 0 -0.0006 13 0 0 0 1.75E+07 1.57E+07 - - - 6.6789 1 221125_WJC_METTL3_EV_vs_WT_F03.23413.23413.2 4.68E-10 19/34 K.ISSIQSIVPALEIANAHR[166.11].K "sp|P10809|CH60_HUMAN,tr|A0A7I2V2X6|A0A7I2V2X6_HUMAN,tr|A0A7I2YQK6|A0A7I2YQK6_HUMAN,tr|A0A7I2V599|A0A7I2V599_HUMAN,tr|A0A7I2YQ71|A0A7I2YQ71_HUMAN,tr|A0A7I2V5M1|A0A7I2V5M1_HUMAN,tr|A0A7I2V5K3|A0A7I2V5K3_HUMAN,tr|A0A7I2V369|A0A7I2V369_HUMAN" 8 1928.0719 1.33 37939 23413 2 1928.072273 965.0432 "60 kDa heat shock protein, mitochondrial OS=Homo sapiens OX=9606 GN=HSPD1 PE=1 SV=2" 6.75 3663 - 450090 - - - 0.2038 - 3.504 0.626 - 698.8 1 2 0 0.0004 18 0 0 0 6.52E+08 4.92E+08 - - - 6.7473 0.9979 221125_WJC_METTL3_EV_vs_WT_F03.23416.23416.3 0.00171 Nov-56 K.QC[160.03]ANLQNAIADAEQR.G "sp|P13647|K2C5_HUMAN,tr|H0YI76|H0YI76_HUMAN" 2 1700.79 7.63 37941 23416 3 1700.793706 567.9373 "Keratin, type II cytoskeletal 5 OS=Homo sapiens OX=9606 GN=KRT5 PE=1 SV=3" 4.37 3663.3 - 883893 - - - 2.1608 - 1.849 0.285 - 103.5 1 2 0 0.0037 15 0 0 0 5.01E+06 6.57E+05 - - - 3.3203 0.9999 221125_WJC_METTL3_EV_vs_WT_F03.23418.23418.3 0.000118 15/56 R.ETNGLLQEELEGLQR.K sp|Q9Y6D9|MD1L1_HUMAN 1 1727.869 2.08 37943 23418 3 1727.869096 576.9636 Mitotic spindle assembly checkpoint protein MAD1 OS=Homo sapiens OX=9606 GN=MAD1L1 PE=1 SV=2 4.09 3663.4 - 3.65E+06 - - - 0.0596 - 2.548 0.402 - 310.7 1 2 0 0.0001 15 0 0 0 2.42E+07 1.16E+07 - - - 5.4624 1 221125_WJC_METTL3_EV_vs_WT_F03.23421.23421.3 4.61E-05 13/48 R.DITLFHAMDTLQR.N sp|O94776|MTA2_HUMAN 1 1559.7766 1.12 37946 23421 3 1559.776171 520.9328 Metastasis-associated protein MTA2 OS=Homo sapiens OX=9606 GN=MTA2 PE=1 SV=1 5.21 3663.6 - 1.82E+06 - - - -0.2834 - 2.545 0.529 - 166.5 1 2 0 -0.0004 13 0 0 0 1.75E+07 1.57E+07 - - - 6.9704 0.9999 221125_WJC_METTL3_EV_vs_WT_F03.23422.23422.3 0.000205 16/44 K.SQLQDTLIHLIK.N sp|Q9NPI6|DCP1A_HUMAN 1 1407.8086 2.3 37947 23422 3 1407.807697 470.2768 mRNA-decapping enzyme 1A OS=Homo sapiens OX=9606 GN=DCP1A PE=1 SV=3 6.46 3663.7 - 1.46E+06 - - - -0.6166 - 2.487 0.414 - 436.9 1 2 0 -0.0009 12 0 0 0 7.26E+07 3.16E+07 - - - 5.6808 0.9998 221125_WJC_METTL3_EV_vs_WT_F03.23423.23423.3 0.000825 16/64 K.ELQELNELFK[136.11]PVVAAQK[136.11].L "sp|Q8WU90|ZC3HF_HUMAN,tr|F8WB26|F8WB26_HUMAN" 2 1971.1012 0.19 37948 23423 3 1971.097809 658.041 Zinc finger CCCH domain-containing protein 15 OS=Homo sapiens OX=9606 GN=ZC3H15 PE=1 SV=1 4.79 3663.8 - 1.40E+06 - - - -1.7092 - 2.41 0.396 - 268.9 1 2 0 -0.0034 17 0 0 0 2.11E+06 1.12E+07 - - - 5.1763 1 221125_WJC_METTL3_EV_vs_WT_F03.23425.23425.2 3.48E-07 13/40 M.VGGGGVGGGLLENANPLIYQR.S "sp|Q9Y3D0|CIA2B_HUMAN,tr|H3BNV7|H3BNV7_HUMAN,tr|J3QLT9|J3QLT9_HUMAN" 3 2040.0752 999 37950 23425 2 2040.080625 1021.0449 Cytosolic iron-sulfur assembly component 2B OS=Homo sapiens OX=9606 GN=CIAO2B PE=1 SV=1 5.97 3664 - 876426 - - - 2.6406 - 2.778 0.571 - 262.6 1 2 0 0.0054 21 0 0 0 6.30E+06 0.00E+00 - - - 5.7687 1 221125_WJC_METTL3_EV_vs_WT_F03.23426.23426.3 3.29E-06 17/44 K.SQLQDTLIHLIK[136.11].N sp|Q9NPI6|DCP1A_HUMAN 1 1415.8228 2.3 37951 23426 3 1415.822693 472.9482 mRNA-decapping enzyme 1A OS=Homo sapiens OX=9606 GN=DCP1A PE=1 SV=3 6.46 3664.1 - 649561 - - - -0.0509 - 2.405 0.474 - 459.3 1 2 0 -0.0001 12 0 0 0 7.26E+07 3.16E+07 - - - 6.257 1 221125_WJC_METTL3_EV_vs_WT_F03.23431.23431.2 7.67E-12 19/32 K.VNVDIINFGEEEVNTEK.L "sp|P55036|PSMD4_HUMAN,sp|A2A3N6|PIPSL_HUMAN,tr|A6PVX3|A6PVX3_HUMAN,tr|Q5VWC4|Q5VWC4_HUMAN" 4 1947.9426 1.45 37954 23431 2 1947.943833 974.9786 26S proteasome non-ATPase regulatory subunit 4 OS=Homo sapiens OX=9606 GN=PSMD4 PE=1 SV=1 3.91 3664.7 - 5.51E+06 - - - 0.6576 - 3.766 0.67 - 933.3 1 2 0 0.0013 17 0 0 0 5.81E+07 4.01E+07 - - - 7.2493 0.9904 221125_WJC_METTL3_EV_vs_WT_F03.23432.23432.2 1.16E-09 Nov-32 K.SQDDEIGDGTTGVVVLA.G "sp|P48643|TCPE_HUMAN,tr|E9PCA1|E9PCA1_HUMAN,tr|B7ZAR1|B7ZAR1_HUMAN" 3 1674.7948 - 37955 23432 2 1674.794142 838.4047 T-complex protein 1 subunit epsilon OS=Homo sapiens OX=9606 GN=CCT5 PE=1 SV=1 3.37 3664.8 - 2.41E+06 - - - -0.4078 - 2.311 0.448 - 259.2 1 1 0 -0.0007 17 0 0 0 - - - - - 4.4092 1 221125_WJC_METTL3_EV_vs_WT_F03.23433.23433.2 5.33E-09 20/32 K.VNVDIINFGEEEVNTEK[136.11].L "sp|P55036|PSMD4_HUMAN,sp|A2A3N6|PIPSL_HUMAN,tr|A6PVX3|A6PVX3_HUMAN,tr|Q5VWC4|Q5VWC4_HUMAN" 4 1955.9568 1.45 37956 23433 2 1955.953846 978.9857 26S proteasome non-ATPase regulatory subunit 4 OS=Homo sapiens OX=9606 GN=PSMD4 PE=1 SV=1 3.91 3664.9 - 3.73E+06 - - - -1.4857 - 3.749 0.66 - 984.6 1 2 0 -0.0029 17 0 0 0 5.81E+07 4.01E+07 - - - 7.1638 1 221125_WJC_METTL3_EV_vs_WT_F03.23434.23434.3 6.71E-13 17/56 R.YLTAEETDK[136.11]IINYLR[166.11].E sp|Q9HCD5|NCOA5_HUMAN 1 1858.9796 1.95 37957 23434 3 1858.980958 620.6671 Nuclear receptor coactivator 5 OS=Homo sapiens OX=9606 GN=NCOA5 PE=1 SV=2 4.68 3664.9 - 3.17E+06 - - - 0.7574 - 3.377 0.637 - 315.1 1 2 1 0.0014 15 0 0 0 1.31E+08 6.70E+07 - - - 8.8171 0.9997 221125_WJC_METTL3_EV_vs_WT_F03.23435.23435.2 7.68E-07 14/22 K.DAGVIAGLNVLR.L "sp|P0DMV8|HS71A_HUMAN,sp|P34931|HS71L_HUMAN,sp|P0DMV9|HS71B_HUMAN,tr|Q53FA3|Q53FA3_HUMAN,tr|A0A0G2JIW1|A0A0G2JIW1_HUMAN" 5 1196.6877 0.13 37958 23435 2 1196.688951 599.3511 Heat shock 70 kDa protein 1A OS=Homo sapiens OX=9606 GN=HSPA1A PE=1 SV=1 5.84 3665 - 1.96E+06 - - - 1.0278 - 2.656 0.347 - 754.5 1 2 0 0.0012 12 0 0 0 1.39E+07 1.07E+08 - - - 4.1737 0.9999 221125_WJC_METTL3_EV_vs_WT_F03.23437.23437.3 6.87E-09 14/60 R.LK[136.11]VPPAINQFTQALDR[166.11].Q "sp|P62424|RL7A_HUMAN,tr|Q5T8U3|Q5T8U3_HUMAN" 2 1828.0326 0.24 37960 23437 3 1828.029794 610.3515 60S ribosomal protein L7a OS=Homo sapiens OX=9606 GN=RPL7A PE=1 SV=2 8.75 3665.2 - 1.67E+06 - - - -1.5284 - 2.946 0.592 - 293.5 1 2 1 -0.0028 16 0 0 0 5.56E+06 2.29E+07 - - - 7.9117 1 221125_WJC_METTL3_EV_vs_WT_F03.23438.23438.3 3.94E-08 16/52 K.K[136.11]GIDYDFPSLILQK[136.11].T "sp|Q9BYG3|MK67I_HUMAN,tr|C9J808|C9J808_HUMAN,tr|C9J6C5|C9J6C5_HUMAN" 3 1651.9156 1.56 37961 23438 3 1651.915082 551.6458 MKI67 FHA domain-interacting nucleolar phosphoprotein OS=Homo sapiens OX=9606 GN=NIFK PE=1 SV=1 5.96 3665.3 - 1.43E+06 - - - -0.319 - 2.802 0.546 - 256.1 1 2 0 -0.0005 14 0 0 0 3.32E+07 2.12E+07 - - - 7.3654 1 221125_WJC_METTL3_EV_vs_WT_F03.23442.23442.2 3.11E-09 15/32 K.LQSSDGEIFEVDVEIAK.Q "sp|P63208|SKP1_HUMAN,tr|E5RI56|E5RI56_HUMAN,tr|E5RGM3|E5RGM3_HUMAN,tr|E5RHM3|E5RHM3_HUMAN,tr|E5RJR5|E5RJR5_HUMAN,tr|E7ERH2|E7ERH2_HUMAN,tr|E5RGM4|E5RGM4_HUMAN,tr|F8W8N3|F8W8N3_HUMAN" 8 1877.9258 999 37965 23442 2 1877.92362 939.9702 S-phase kinase-associated protein 1 OS=Homo sapiens OX=9606 GN=SKP1 PE=1 SV=2 3.83 3665.8 - 697692 - - - -1.1816 - 3.42 0.621 - 569.2 1 2 0 -0.0022 17 0 0 0 8.28E+06 0.00E+00 - - - 6.6501 1 221125_WJC_METTL3_EV_vs_WT_F03.23446.23446.3 9.74E-13 21/96 R.VIKDFMIQGGDFVNGDGTGVASIYR.G "sp|O43447|PPIH_HUMAN,tr|A0A7I2YQS4|A0A7I2YQS4_HUMAN,tr|C9JQD4|C9JQD4_HUMAN" 3 2658.3112 2.94 37967 23446 3 2658.311673 887.111 Peptidyl-prolyl cis-trans isomerase H OS=Homo sapiens OX=9606 GN=PPIH PE=1 SV=1 4.43 3666.3 - 8.42E+06 - - - 0.1828 - 3.312 0.699 - 476 1 2 1 0.0005 25 0 0 0 7.16E+07 2.44E+07 - - - 9.0882 1 221125_WJC_METTL3_EV_vs_WT_F03.23447.23447.4 2.18E-15 22/120 K.FENAFLSHVVSQHQALLGTIR.A sp|P25705|ATPA_HUMAN 1 2366.2495 1.31 37968 23447 4 2366.249958 592.5697 "ATP synthase subunit alpha, mitochondrial OS=Homo sapiens OX=9606 GN=ATP5F1A PE=1 SV=1" 6.92 3666.4 - 8.03E+06 - - - 0.1876 - 3.735 0.683 - 336.2 1 2 0 0.0004 21 0 0 0 1.39E+08 1.06E+08 - - - 5.6064 1 221125_WJC_METTL3_EV_vs_WT_F03.23448.23448.3 2.98E-12 23/76 K.FEAHPNDLYVEGLPENIPFR.S "sp|P78347|GTF2I_HUMAN,tr|A0A494C0Q7|A0A494C0Q7_HUMAN,tr|A0A494C1K3|A0A494C1K3_HUMAN" 3 2356.1488 1.76 37969 23448 3 2356.146358 786.3902 General transcription factor II-I OS=Homo sapiens OX=9606 GN=GTF2I PE=1 SV=2 4.4 3666.4 - 2.98E+06 - - - -1.0352 - 3.982 0.678 - 414.7 1 2 0 -0.0024 20 0 0 0 2.90E+09 1.65E+09 - - - 9.4506 1 221125_WJC_METTL3_EV_vs_WT_F03.23449.23449.3 4.26E-10 16/68 K.ITLPVDFVTADKFDENAK.T sp|P00558|PGK1_HUMAN 1 2022.031 1.18 37970 23449 3 2022.032546 675.0176 Phosphoglycerate kinase 1 OS=Homo sapiens OX=9606 GN=PGK1 PE=1 SV=3 4.23 3666.5 - 2.86E+06 - - - 0.7779 - 3.137 0.615 - 265.2 1 2 1 0.0016 18 0 0 0 3.96E+07 3.35E+07 - - - 8.2431 0.9999 221125_WJC_METTL3_EV_vs_WT_F03.23450.23450.3 1.88E-11 22/88 R.AVLIDEVC[160.03]TMNDGPHSALYTMMK.D "sp|Q14671|PUM1_HUMAN,tr|Q5T1Z8|Q5T1Z8_HUMAN,tr|H0YDK8|H0YDK8_HUMAN,tr|H0YEH2|H0YEH2_HUMAN,tr|Q5T1Z4|Q5T1Z4_HUMAN,tr|E9PR38|E9PR38_HUMAN" 6 2595.1841 2.55 37971 23450 3 2595.183417 866.0687 Pumilio homolog 1 OS=Homo sapiens OX=9606 GN=PUM1 PE=1 SV=3 4.54 3666.6 - 2.84E+06 - - - -0.2778 - 4.177 0.324 - 452.1 1 2 0 -0.0007 23 0 0 0 5.06E+07 1.98E+07 - - - 5.5058 0.9999 221125_WJC_METTL3_EV_vs_WT_F03.23451.23451.3 1.05E-05 15/52 R.SRPPLQDDLLFFEK.A "sp|Q15390|MTFR1_HUMAN,tr|H0YBZ4|H0YBZ4_HUMAN" 2 1703.8883 2.44 37972 23451 3 1703.893231 568.97 Mitochondrial fission regulator 1 OS=Homo sapiens OX=9606 GN=MTFR1 PE=1 SV=2 4.56 3666.7 - 1.89E+06 - - - 2.9104 - 3.241 0.453 - 309.3 1 2 0 0.005 14 0 0 0 3.16E+07 1.29E+07 - - - 6.7141 0.9999 221125_WJC_METTL3_EV_vs_WT_F03.23453.23453.2 0.0121 17/34 K.ISSIQSIVPALEIANAHR.K "sp|P10809|CH60_HUMAN,tr|A0A7I2V2X6|A0A7I2V2X6_HUMAN,tr|A0A7I2YQK6|A0A7I2YQK6_HUMAN,tr|A0A7I2V599|A0A7I2V599_HUMAN,tr|A0A7I2YQ71|A0A7I2YQ71_HUMAN,tr|A0A7I2V5M1|A0A7I2V5M1_HUMAN,tr|A0A7I2V5K3|A0A7I2V5K3_HUMAN,tr|A0A7I2V369|A0A7I2V369_HUMAN" 8 1918.0636 1.33 37974 23453 2 1918.062566 960.0391 "60 kDa heat shock protein, mitochondrial OS=Homo sapiens OX=9606 GN=HSPD1 PE=1 SV=2" 6.75 3667 - 1.53E+06 - - - -0.5443 - 3.309 0.483 - 466.8 1 2 0 -0.001 18 0 0 0 6.52E+08 4.92E+08 - - - 5.5501 0.9993 221125_WJC_METTL3_EV_vs_WT_F03.23455.23455.3 0.0273 Oct-64 K.LLLDMGSDINAQIETNR.N "sp|O75179|ANR17_HUMAN,sp|Q8IWZ3|ANKH1_HUMAN,tr|E9PDP5|E9PDP5_HUMAN,tr|H0YM23|H0YM23_HUMAN,tr|H3BLS9|H3BLS9_HUMAN,tr|H0YLQ3|H0YLQ3_HUMAN,tr|H7C2F5|H7C2F5_HUMAN" 7 1901.9517 0.77 37976 23455 3 1901.95097 634.9912 Ankyrin repeat domain-containing protein 17 OS=Homo sapiens OX=9606 GN=ANKRD17 PE=1 SV=3 4.03 3667.1 - 1.21E+06 - - - -0.3717 - 2.138 0.28 - 129 1 2 0 -0.0007 17 0 0 0 6.20E+06 8.06E+06 - - - 3.5812 1 221125_WJC_METTL3_EV_vs_WT_F03.23456.23456.3 1.33E-08 18/52 R.R[166.11]LDLVHTAALMLDK[136.11].N "sp|O75643|U520_HUMAN,tr|A0A494C1A5|A0A494C1A5_HUMAN" 2 1612.909 2.24 37977 23456 3 1612.909043 538.6436 U5 small nuclear ribonucleoprotein 200 kDa helicase OS=Homo sapiens OX=9606 GN=SNRNP200 PE=1 SV=2 6.75 3667.2 - 1.17E+06 - - - 0.0465 - 3.306 0.527 - 423.9 1 2 0 0.0001 14 0 0 0 2.39E+07 1.07E+07 - - - 7.5932 1 221125_WJC_METTL3_EV_vs_WT_F03.23457.23457.2 4.58E-12 17/30 R.EEEVTGPVIAPLFPQK.R sp|O75643|U520_HUMAN 1 1752.9298 4.98 37978 23457 2 1752.933074 877.4722 U5 small nuclear ribonucleoprotein 200 kDa helicase OS=Homo sapiens OX=9606 GN=SNRNP200 PE=1 SV=2 4.25 3667.3 - 1.05E+06 - - - 1.8666 - 2.858 0.613 - 864.4 1 2 0 0.0033 16 0 0 0 2.39E+07 4.79E+06 - - - 6.1494 1 221125_WJC_METTL3_EV_vs_WT_F03.23458.23458.3 2.86E-05 15/48 R.KAIIIFVPVPQLK.S "sp|P62081|RS7_HUMAN,tr|B5MCP9|B5MCP9_HUMAN" 2 1464.9432 0.77 37979 23458 3 1464.944015 489.3217 40S ribosomal protein S7 OS=Homo sapiens OX=9606 GN=RPS7 PE=1 SV=1 10 3667.4 - 858385 - - - 0.5509 - 2.262 0.598 - 310.6 1 2 0 0.0008 13 0 0 0 2.46E+07 3.20E+07 - - - 7.42 1 221125_WJC_METTL3_EV_vs_WT_F03.23459.23459.2 1.04E-07 14/34 R.MDSLLIAGQINTYC[160.03]QNIK[136.11].E "sp|O15372|EIF3H_HUMAN,tr|B3KS98|B3KS98_HUMAN,tr|A0A087WZK9|A0A087WZK9_HUMAN" 3 2089.0427 -1 37980 23459 2 2089.042403 1045.5286 Eukaryotic translation initiation factor 3 subunit H OS=Homo sapiens OX=9606 GN=EIF3H PE=1 SV=1 5.58 3667.6 - 513398 - - - -0.1647 - 3.436 0.578 - 642.3 1 2 0 -0.0003 18 0 0 0 0.00E+00 0.00E+00 - - - 6.3446 1 221125_WJC_METTL3_EV_vs_WT_F03.23462.23462.4 2.26E-12 22/120 K.FENAFLSHVVSQHQALLGTIR[166.11].A sp|P25705|ATPA_HUMAN 1 2376.2578 1.31 37981 23462 4 2376.257785 595.0717 "ATP synthase subunit alpha, mitochondrial OS=Homo sapiens OX=9606 GN=ATP5F1A PE=1 SV=1" 6.92 3668 - 1.16E+07 - - - 0.0004 - 3.743 0.603 - 299.1 1 2 0 0 21 0 0 0 1.39E+08 1.06E+08 - - - 4.9109 0.9998 221125_WJC_METTL3_EV_vs_WT_F03.23463.23463.2 0.0286 13/22 K.TDTLEDLFPTTK.L sp|P13010|XRCC5_HUMAN 1 1379.682 1.11 37982 23463 2 1379.680134 690.8483 X-ray repair cross-complementing protein 5 OS=Homo sapiens OX=9606 GN=XRCC5 PE=1 SV=3 4.03 3668 - 4.92E+06 - - - -1.3721 - 2.646 0.443 - 495.6 1 2 0 -0.0019 12 0 0 0 2.01E+08 1.81E+08 - - - 4.8727 1 221125_WJC_METTL3_EV_vs_WT_F03.23465.23465.3 6.20E-18 27/80 K.FENAFLSHVVSQHQALLGTIR[166.11].A sp|P25705|ATPA_HUMAN 1 2376.2578 0.88 37984 23465 3 2376.260366 793.0932 "ATP synthase subunit alpha, mitochondrial OS=Homo sapiens OX=9606 GN=ATP5F1A PE=1 SV=1" 6.92 3668.2 - 2.63E+06 - - - 1.0866 - 4.694 0.721 - 875.1 1 2 0 0.0026 21 0 0 0 1.75E+07 1.99E+07 - - - 10.2849 1 221125_WJC_METTL3_EV_vs_WT_F03.23467.23467.2 4.14E-06 18/30 K.TESAVSQMQSVIELGR[166.11].V "sp|P41252|SYIC_HUMAN,tr|A0A804HL54|A0A804HL54_HUMAN,tr|A0A804HIV9|A0A804HIV9_HUMAN,tr|A0A804HJN6|A0A804HJN6_HUMAN,tr|A0A804HHW9|A0A804HHW9_HUMAN,tr|A0A0A0MSX9|A0A0A0MSX9_HUMAN,tr|J3KR24|J3KR24_HUMAN,tr|A0A804HJ36|A0A804HJ36_HUMAN" 8 1743.8701 0.78 37986 23467 2 1743.868128 872.9423 "Isoleucine--tRNA ligase, cytoplasmic OS=Homo sapiens OX=9606 GN=IARS1 PE=1 SV=2" 4.53 3668.4 - 1.88E+06 - - - -1.113 - 3.343 0.561 - 420.5 1 2 0 -0.0019 16 0 0 0 3.37E+07 4.34E+07 - - - 6.1511 0.999 221125_WJC_METTL3_EV_vs_WT_F03.23468.23468.3 1.29E-09 18/56 A.INGIVFLVDC[160.03]ADHSR.L "sp|Q9NR31|SAR1A_HUMAN,tr|Q5SQT8|Q5SQT8_HUMAN" 2 1714.8461 0.74 37987 23468 3 1714.846998 572.6226 GTP-binding protein SAR1a OS=Homo sapiens OX=9606 GN=SAR1A PE=1 SV=1 5.21 3668.5 - 1.72E+06 - - - 0.5295 - 3.418 0.592 - 552.8 1 1 0 0.0009 15 0 0 0 2.40E+07 3.23E+07 - - - 8.347 1 221125_WJC_METTL3_EV_vs_WT_F03.23469.23469.3 2.03E-07 14/52 R.SR[166.11]PPLQDDLLFFEK[136.11].A "sp|Q15390|MTFR1_HUMAN,tr|H0YBZ4|H0YBZ4_HUMAN" 2 1721.9107 2.44 37988 23469 3 1721.908995 574.9775 Mitochondrial fission regulator 1 OS=Homo sapiens OX=9606 GN=MTFR1 PE=1 SV=2 4.56 3668.6 - 1.69E+06 - - - -1.0146 - 2.677 0.488 - 196.8 1 2 0 -0.0017 14 0 0 0 3.16E+07 1.29E+07 - - - 6.5971 1 221125_WJC_METTL3_EV_vs_WT_F03.23472.23472.2 2.29E-07 18/28 R.YLTAEETDKIINYLR.E sp|Q9HCD5|NCOA5_HUMAN 1 1840.9571 4.83 37991 23472 2 1840.959548 921.4858 Nuclear receptor coactivator 5 OS=Homo sapiens OX=9606 GN=NCOA5 PE=1 SV=2 4.68 3668.9 - 767412 - - - 1.3406 - 3.366 0.564 - 1283.8 1 2 1 0.0025 15 0 0 0 6.62E+06 1.37E+06 - - - 6.1899 0.9902 221125_WJC_METTL3_EV_vs_WT_F03.23473.23473.3 3.62E-05 17/44 K.VSILESLDK[136.11]WER[166.11].L "sp|P10644|KAP0_HUMAN,tr|K7EM13|K7EM13_HUMAN,tr|K7EPB2|K7EPB2_HUMAN" 3 1491.8052 0.84 37992 23473 3 1491.79829 498.2757 cAMP-dependent protein kinase type I-alpha regulatory subunit OS=Homo sapiens OX=9606 GN=PRKAR1A PE=1 SV=1 4.68 3669.1 - 757278 - - - -4.6414 - 2.833 0.293 - 527.2 1 2 1 -0.0069 12 0 0 0 1.16E+07 1.38E+07 - - - 4.6912 0.9999 221125_WJC_METTL3_EV_vs_WT_F03.23474.23474.3 2.51E-05 17/60 K.TESAVSQMQSVIELGR[166.11].V "sp|P41252|SYIC_HUMAN,tr|A0A804HL54|A0A804HL54_HUMAN,tr|A0A804HIV9|A0A804HIV9_HUMAN,tr|A0A804HJN6|A0A804HJN6_HUMAN,tr|A0A804HHW9|A0A804HHW9_HUMAN,tr|A0A0A0MSX9|A0A0A0MSX9_HUMAN,tr|J3KR24|J3KR24_HUMAN,tr|A0A804HJ36|A0A804HJ36_HUMAN" 8 1743.8701 0.69 37993 23474 3 1743.876506 582.2973 "Isoleucine--tRNA ligase, cytoplasmic OS=Homo sapiens OX=9606 GN=IARS1 PE=1 SV=2" 4.53 3669.2 - 737253 - - - 3.6912 - 3.358 0.482 - 520.1 1 2 0 0.0064 16 0 0 0 9.56E+06 1.38E+07 - - - 7.0202 0.9999 221125_WJC_METTL3_EV_vs_WT_F03.23477.23477.3 0.000919 17/56 R.YLTAEETDKIINYLR.E sp|Q9HCD5|NCOA5_HUMAN 1 1840.9571 1.82 37995 23477 3 1840.958468 614.6596 Nuclear receptor coactivator 5 OS=Homo sapiens OX=9606 GN=NCOA5 PE=1 SV=2 4.68 3669.6 - 1.14E+07 - - - 0.754 - 3.299 0.562 - 315.4 1 2 1 0.0014 15 0 0 0 1.29E+08 7.10E+07 - - - 7.92 1 221125_WJC_METTL3_EV_vs_WT_F03.23479.23479.2 5.59E-08 18/32 R.IQEIIEQLDVTTSEYEK.E "sp|P10809|CH60_HUMAN,tr|A0A7I2V2X6|A0A7I2V2X6_HUMAN,tr|A0A7I2YQK6|A0A7I2YQK6_HUMAN,tr|A0A7I2V599|A0A7I2V599_HUMAN" 4 2037.0154 1.34 37997 23479 2 2037.014423 1019.515 "60 kDa heat shock protein, mitochondrial OS=Homo sapiens OX=9606 GN=HSPD1 PE=1 SV=2" 3.91 3669.7 - 3.08E+06 - - - -0.4708 - 3.859 0.612 - 810.4 1 2 0 -0.001 17 0 0 0 2.53E+09 1.89E+09 - - - 6.881 1 221125_WJC_METTL3_EV_vs_WT_F03.23480.23480.3 3.58E-10 17/56 A.INGIVFLVDC[160.03]ADHSR[166.11].L "sp|Q9NR31|SAR1A_HUMAN,tr|Q5SQT8|Q5SQT8_HUMAN" 2 1724.8544 1.15 37998 23480 3 1724.850683 575.9587 GTP-binding protein SAR1a OS=Homo sapiens OX=9606 GN=SAR1A PE=1 SV=1 5.21 3669.7 - 2.16E+06 - - - -2.1318 - 3.102 0.629 - 439.7 1 1 0 -0.0037 15 0 0 0 2.28E+07 1.99E+07 - - - 8.5056 1 221125_WJC_METTL3_EV_vs_WT_F03.23481.23481.3 7.42E-07 20/52 R.RLDLVHTAALMLDK.N "sp|O75643|U520_HUMAN,tr|A0A494C1A5|A0A494C1A5_HUMAN" 2 1594.8865 2.24 37999 23481 3 1594.88724 532.6361 U5 small nuclear ribonucleoprotein 200 kDa helicase OS=Homo sapiens OX=9606 GN=SNRNP200 PE=1 SV=2 6.75 3669.8 - 1.61E+06 - - - 0.4652 - 3.897 0.57 - 660.3 1 2 0 0.0007 14 0 0 0 2.39E+07 1.07E+07 - - - 8.5095 1 221125_WJC_METTL3_EV_vs_WT_F03.23485.23485.3 9.28E-08 16/60 K.TESAVSQMQSVIELGR.V "sp|P41252|SYIC_HUMAN,tr|A0A804HL54|A0A804HL54_HUMAN,tr|A0A804HIV9|A0A804HIV9_HUMAN,tr|A0A804HJN6|A0A804HJN6_HUMAN,tr|A0A804HHW9|A0A804HHW9_HUMAN,tr|A0A0A0MSX9|A0A0A0MSX9_HUMAN,tr|J3KR24|J3KR24_HUMAN,tr|A0A804HJ36|A0A804HJ36_HUMAN" 8 1733.8618 0.69 38002 23485 3 1733.86009 578.9612 "Isoleucine--tRNA ligase, cytoplasmic OS=Homo sapiens OX=9606 GN=IARS1 PE=1 SV=2" 4.53 3670.2 - 1.60E+06 - - - -0.9857 - 3.157 0.565 - 366.6 1 2 0 -0.0017 16 0 0 0 9.56E+06 1.38E+07 - - - 7.7885 1 221125_WJC_METTL3_EV_vs_WT_F03.23487.23487.3 1.04E-10 19/64 R.IQEIIEQLDVTTSEYEK.E "sp|P10809|CH60_HUMAN,tr|A0A7I2V2X6|A0A7I2V2X6_HUMAN,tr|A0A7I2YQK6|A0A7I2YQK6_HUMAN,tr|A0A7I2V599|A0A7I2V599_HUMAN" 4 2037.0154 1.34 38003 23487 3 2037.01126 680.0124 "60 kDa heat shock protein, mitochondrial OS=Homo sapiens OX=9606 GN=HSPD1 PE=1 SV=2" 3.91 3670.5 - 1.62E+07 - - - -2.0235 - 3.39 0.645 - 648.7 1 2 0 -0.0041 17 0 0 0 3.74E+09 2.80E+09 - - - 8.8142 1 221125_WJC_METTL3_EV_vs_WT_F03.23488.23488.2 8.48E-12 17/34 K.TSGVPSGFNFTAPPVLGK.H "sp|P35658|NU214_HUMAN,tr|A0A0A0MSW3|A0A0A0MSW3_HUMAN,tr|E9PKD2|E9PKD2_HUMAN,tr|B7ZAV2|B7ZAV2_HUMAN,tr|A0A494C1F2|A0A494C1F2_HUMAN,tr|H0Y837|H0Y837_HUMAN" 6 1774.9254 2.54 38004 23488 2 1774.923439 888.47 Nuclear pore complex protein Nup214 OS=Homo sapiens OX=9606 GN=NUP214 PE=1 SV=2 8.41 3670.5 - 9.89E+06 - - - -1.0969 - 2.991 0.692 - 609.5 1 2 0 -0.0019 18 0 0 0 3.19E+08 1.26E+08 - - - 6.8451 1 221125_WJC_METTL3_EV_vs_WT_F03.23489.23489.3 2.93E-09 22/76 R.LALVTGGEIASTFDHPELVK[136.11].L "sp|P78371|TCPB_HUMAN,tr|F8VQ14|F8VQ14_HUMAN,tr|F5GWF6|F5GWF6_HUMAN" 3 2104.1296 0.72 38005 23489 3 2104.127987 702.3838 T-complex protein 1 subunit beta OS=Homo sapiens OX=9606 GN=CCT2 PE=1 SV=4 4.65 3670.5 - 8.44E+06 - - - -0.7528 - 3.58 0.588 - 456.4 1 2 0 -0.0016 20 0 0 0 1.08E+08 1.51E+08 - - - 8.1892 1 221125_WJC_METTL3_EV_vs_WT_F03.23490.23490.4 3.14E-08 18/114 K.FEAHPNDLYVEGLPENIPFR.S "sp|P78347|GTF2I_HUMAN,tr|A0A494C0Q7|A0A494C0Q7_HUMAN,tr|A0A494C1K3|A0A494C1K3_HUMAN" 3 2356.1488 2.06 38006 23490 4 2356.145034 590.0445 General transcription factor II-I OS=Homo sapiens OX=9606 GN=GTF2I PE=1 SV=2 4.4 3670.6 - 3.29E+06 - - - -1.5971 - 3.153 0.51 - 214.4 1 2 0 -0.0038 20 0 0 0 9.47E+07 4.60E+07 - - - 4.0479 1 221125_WJC_METTL3_EV_vs_WT_F03.23492.23492.3 0.00181 23/80 K.AQLQQVEAALSGNGENEDLLK.L "sp|O75940|SPF30_HUMAN,tr|A0A6Q8PFX6|A0A6Q8PFX6_HUMAN,tr|A0A6Q8PG47|A0A6Q8PG47_HUMAN" 3 2226.1128 1.64 38008 23492 3 2226.118015 743.0449 Survival of motor neuron-related-splicing factor 30 OS=Homo sapiens OX=9606 GN=SMNDC1 PE=1 SV=1 4 3670.7 - 2.02E+06 - - - 2.3404 - 4.767 0.579 - 709.4 1 2 0 0.0052 21 0 0 0 3.82E+07 2.33E+07 - - - 8.738 1 221125_WJC_METTL3_EV_vs_WT_F03.23494.23494.2 6.29E-14 21/38 K.FEAHPNDLYVEGLPENIPFR.S "sp|P78347|GTF2I_HUMAN,tr|A0A494C0Q7|A0A494C0Q7_HUMAN,tr|A0A494C1K3|A0A494C1K3_HUMAN" 3 2356.1488 2.27 38010 23494 2 2356.147044 1179.0817 General transcription factor II-I OS=Homo sapiens OX=9606 GN=GTF2I PE=1 SV=2 4.4 3671 - 1.11E+06 - - - -0.744 - 3.703 0.721 - 809.2 1 2 0 -0.0018 20 0 0 0 7.46E+07 3.29E+07 - - - 7.5843 1 221125_WJC_METTL3_EV_vs_WT_F03.23499.23499.3 6.44E-08 17/64 R.IQEIIEQLDVTTSEYEK[136.11].E "sp|P10809|CH60_HUMAN,tr|A0A7I2V2X6|A0A7I2V2X6_HUMAN,tr|A0A7I2YQK6|A0A7I2YQK6_HUMAN,tr|A0A7I2V599|A0A7I2V599_HUMAN" 4 2045.0296 1.34 38013 23499 3 2045.025735 682.6838 "60 kDa heat shock protein, mitochondrial OS=Homo sapiens OX=9606 GN=HSPD1 PE=1 SV=2" 3.91 3671.7 - 4.08E+07 - - - -1.8811 - 3.123 0.588 - 510.3 1 2 0 -0.0038 17 0 0 0 3.74E+09 2.80E+09 - - - 7.9715 0.9999 221125_WJC_METTL3_EV_vs_WT_F03.23500.23500.2 3.60E-08 13/22 K.TDTLEDLFPTTK[136.11].L sp|P13010|XRCC5_HUMAN 1 1387.6962 1.12 38014 23500 2 1387.695334 694.8554 X-ray repair cross-complementing protein 5 OS=Homo sapiens OX=9606 GN=XRCC5 PE=1 SV=3 4.03 3671.7 - 5.39E+06 - - - -0.6435 - 2.512 0.547 - 583.5 1 2 0 -0.0009 12 0 0 0 2.01E+08 1.80E+08 - - - 5.5044 1 221125_WJC_METTL3_EV_vs_WT_F03.23502.23502.2 5.19E-12 14/34 K.TSGVPSGFNFTAPPVLGK[136.11].H "sp|P35658|NU214_HUMAN,tr|A0A0A0MSW3|A0A0A0MSW3_HUMAN,tr|E9PKD2|E9PKD2_HUMAN,tr|B7ZAV2|B7ZAV2_HUMAN,tr|A0A494C1F2|A0A494C1F2_HUMAN,tr|H0Y837|H0Y837_HUMAN" 6 1782.9396 2.54 38016 23502 2 1782.939312 892.4771 Nuclear pore complex protein Nup214 OS=Homo sapiens OX=9606 GN=NUP214 PE=1 SV=2 8.41 3671.8 - 5.87E+06 - - - -0.1537 - 2.865 0.697 - 394.8 1 2 0 -0.0003 18 0 0 0 3.19E+08 1.26E+08 - - - 6.7767 1 221125_WJC_METTL3_EV_vs_WT_F03.23503.23503.3 9.35E-05 20/76 R.LALVTGGEIASTFDHPELVK.L "sp|P78371|TCPB_HUMAN,tr|F8VQ14|F8VQ14_HUMAN,tr|F5GWF6|F5GWF6_HUMAN" 3 2096.1154 0.72 38017 23503 3 2096.112335 699.7124 T-complex protein 1 subunit beta OS=Homo sapiens OX=9606 GN=CCT2 PE=1 SV=4 4.65 3671.9 - 5.66E+06 - - - -1.4484 - 3.592 0.486 - 327.1 1 2 0 -0.003 20 0 0 0 1.09E+08 1.51E+08 - - - 7.0598 1 221125_WJC_METTL3_EV_vs_WT_F03.23506.23506.2 1.06E-11 16/32 K.NSTAFYNNAEVFEVVER.V "sp|P42694|HELZ_HUMAN,tr|J3QS41|J3QS41_HUMAN" 2 1987.9276 3.3 38020 23506 2 1987.928857 994.9711 Probable helicase with zinc finger domain OS=Homo sapiens OX=9606 GN=HELZ PE=1 SV=2 4.25 3672.3 - 1.68E+06 - - - 0.6474 - 3.466 0.679 - 875.2 1 2 0 0.0013 17 0 0 0 1.98E+07 6.02E+06 - - - 7.1117 1 221125_WJC_METTL3_EV_vs_WT_F03.23512.23512.3 8.80E-11 18/76 K.VEDMAELTC[160.03]LNEASVLHNLK[136.11].D "sp|P35580|MYH10_HUMAN,sp|P35579|MYH9_HUMAN,tr|Q5BKV1|Q5BKV1_HUMAN,tr|E7ERA5|E7ERA5_HUMAN,tr|B1AH99|B1AH99_HUMAN" 5 2293.1174 0.5 38025 23512 3 2293.104735 765.3797 Myosin-10 OS=Homo sapiens OX=9606 GN=MYH10 PE=1 SV=3 4.4 3672.9 - 6.30E+06 - - - -5.5095 - 2.922 0.694 - 316.9 1 2 0 -0.0126 20 0 0 0 6.90E+07 1.37E+08 - - - 8.8753 1 221125_WJC_METTL3_EV_vs_WT_F03.23518.23518.4 6.37E-08 30/102 K.ISSIQSIVPALEIANAHR.K "sp|P10809|CH60_HUMAN,tr|A0A7I2V2X6|A0A7I2V2X6_HUMAN,tr|A0A7I2YQK6|A0A7I2YQK6_HUMAN,tr|A0A7I2V599|A0A7I2V599_HUMAN,tr|A0A7I2YQ71|A0A7I2YQ71_HUMAN,tr|A0A7I2V5M1|A0A7I2V5M1_HUMAN,tr|A0A7I2V5K3|A0A7I2V5K3_HUMAN,tr|A0A7I2V369|A0A7I2V369_HUMAN" 8 1918.0636 1.28 38029 23518 4 1918.059041 480.5232 "60 kDa heat shock protein, mitochondrial OS=Homo sapiens OX=9606 GN=HSPD1 PE=1 SV=2" 6.75 3673.4 - 4.25E+06 - - - -2.3821 - 4.011 0.566 - 887.2 1 2 0 -0.0046 18 0 0 0 8.37E+07 6.55E+07 - - - 4.627 0.9999 221125_WJC_METTL3_EV_vs_WT_F03.23519.23519.3 0.000333 17/84 R.VANVPNTSLLVNIPQPTPASLK.G sp|Q86YP4|P66A_HUMAN 1 2272.2791 2.21 38030 23519 3 2272.275793 758.4336 Transcriptional repressor p66-alpha OS=Homo sapiens OX=9606 GN=GATAD2A PE=1 SV=1 8.72 3673.6 - 3.32E+06 - - - -1.4479 - 2.703 0.432 - 216.4 1 2 0 -0.0033 22 0 0 0 8.39E+07 3.79E+07 - - - 5.7129 1 221125_WJC_METTL3_EV_vs_WT_F03.23523.23523.2 1.96E-09 20/32 R.IQEIIEQLDVTTSEYEK[136.11].E "sp|P10809|CH60_HUMAN,tr|A0A7I2V2X6|A0A7I2V2X6_HUMAN,tr|A0A7I2YQK6|A0A7I2YQK6_HUMAN,tr|A0A7I2V599|A0A7I2V599_HUMAN" 4 2045.0296 1.34 38033 23523 2 2045.024788 1023.5221 "60 kDa heat shock protein, mitochondrial OS=Homo sapiens OX=9606 GN=HSPD1 PE=1 SV=2" 3.91 3674 - 7.34E+07 - - - -2.3442 - 3.897 0.655 - 1111.2 1 2 0 -0.0048 17 0 0 0 2.53E+09 1.89E+09 - - - 7.2215 1 221125_WJC_METTL3_EV_vs_WT_F03.23529.23529.3 4.37E-08 19/72 K.TILSNQTVDIPENVDITLK[136.11].G "sp|P32969|RL9_HUMAN,tr|D6RAN4|D6RAN4_HUMAN" 2 2120.1456 1.02 38038 23529 3 2120.141763 707.7225 60S ribosomal protein L9 OS=Homo sapiens OX=9606 GN=RPL9 PE=1 SV=1 4.03 3674.6 - 2.93E+06 - - - -1.8169 - 3.602 0.573 - 379.1 1 2 0 -0.0039 19 0 0 0 1.83E+08 1.79E+08 - - - 8.0757 0.9998 221125_WJC_METTL3_EV_vs_WT_F03.23530.23530.3 7.01E-08 13/64 K.NSTAFYNNAEVFEVVER.V "sp|P42694|HELZ_HUMAN,tr|J3QS41|J3QS41_HUMAN" 2 1987.9276 1.92 38039 23530 3 1987.918508 663.6498 Probable helicase with zinc finger domain OS=Homo sapiens OX=9606 GN=HELZ PE=1 SV=2 4.25 3674.7 - 2.26E+06 - - - -4.5585 - 3.035 0.513 - 213.3 1 2 0 -0.0091 17 0 0 0 1.97E+07 1.02E+07 - - - 7.0617 1 221125_WJC_METTL3_EV_vs_WT_F03.23531.23531.2 6.66E-09 15/36 K.TILSNQTVDIPENVDITLK[136.11].G "sp|P32969|RL9_HUMAN,tr|D6RAN4|D6RAN4_HUMAN" 2 2120.1456 1.09 38040 23531 2 2120.144225 1061.0801 60S ribosomal protein L9 OS=Homo sapiens OX=9606 GN=RPL9 PE=1 SV=1 4.03 3674.8 - 1.40E+06 - - - -0.6556 - 3.257 0.575 - 412.6 1 2 0 -0.0014 19 0 0 0 6.98E+07 6.40E+07 - - - 6.1906 1 221125_WJC_METTL3_EV_vs_WT_F03.23535.23535.3 2.73E-09 18/72 K.TILSNQTVDIPENVDITLK.G "sp|P32969|RL9_HUMAN,tr|D6RAN4|D6RAN4_HUMAN" 2 2112.1314 1.02 38042 23535 3 2112.130267 705.0511 60S ribosomal protein L9 OS=Homo sapiens OX=9606 GN=RPL9 PE=1 SV=1 4.03 3675.3 - 4.32E+06 - - - -0.5435 - 3.099 0.587 - 340 1 2 0 -0.0011 19 0 0 0 1.83E+08 1.79E+08 - - - 7.863 0.9999 221125_WJC_METTL3_EV_vs_WT_F03.23536.23536.3 3.84E-07 15/64 R.IEEYNHVLIEETDQLWK[136.11].V "sp|Q14241|ELOA1_HUMAN,tr|A0A024RAC6|A0A024RAC6_HUMAN" 2 2166.0725 1.3 38043 23536 3 2166.065955 723.0314 Elongin-A OS=Homo sapiens OX=9606 GN=ELOA PE=1 SV=2 4.25 3675.4 - 2.30E+06 - - - -2.9985 - 3.217 0.505 - 253.7 1 2 0 -0.0065 17 0 0 0 3.73E+07 2.86E+07 - - - 7.1203 0.7941 221125_WJC_METTL3_EV_vs_WT_F03.23537.23537.3 8.06E-06 15/72 L.TLGNQLDGIHLLDPDVVAR[166.11].F sp|Q86U44|MTA70_HUMAN 1 2055.0988 0 38044 23537 3 2056.106055 686.0402 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 4.41 3675.5 - 2.01E+07 - - - 490.1137 - 2.507 0.489 - 124.3 1 1 0 1.0072 19 0 0 0 9.94E+05 4.40E+08 - - - 5.9709 1 221125_WJC_METTL3_EV_vs_WT_F03.23538.23538.3 2.13E-13 23/84 K.FVDGLMIHSGDPVNYYVDTAVR[166.11].H "sp|P23396|RS3_HUMAN,tr|H0YEU2|H0YEU2_HUMAN,tr|E9PSF4|E9PSF4_HUMAN,tr|E9PL09|E9PL09_HUMAN" 4 2477.1925 0.5 38045 23538 3 2477.184509 826.7381 40S ribosomal protein S3 OS=Homo sapiens OX=9606 GN=RPS3 PE=1 SV=2 4.41 3675.5 - 8.32E+06 - - - -3.2121 - 3.74 0.712 - 403.3 1 2 0 -0.008 22 0 0 0 6.61E+07 1.33E+08 - - - 9.6032 1 221125_WJC_METTL3_EV_vs_WT_F03.23540.23540.2 7.52E-12 19/36 K.TILSNQTVDIPENVDITLK.G "sp|P32969|RL9_HUMAN,tr|D6RAN4|D6RAN4_HUMAN" 2 2112.1314 1.09 38047 23540 2 2112.12998 1057.073 60S ribosomal protein L9 OS=Homo sapiens OX=9606 GN=RPL9 PE=1 SV=1 4.03 3675.8 - 1.71E+06 - - - -0.6794 - 3.581 0.558 - 598.6 1 2 0 -0.0014 19 0 0 0 6.98E+07 6.40E+07 - - - 6.2982 0.9999 221125_WJC_METTL3_EV_vs_WT_F03.23543.23543.2 1.37E-05 22-Dec K.TNNFSAFLANVR.K sp|Q9HBM1|SPC25_HUMAN 1 1352.6837 4.25 38049 23543 2 1352.682536 677.3491 Kinetochore protein Spc25 OS=Homo sapiens OX=9606 GN=SPC25 PE=1 SV=1 9.41 3676.1 - 5.13E+06 - - - -0.8598 - 2.616 0.551 - 627.1 1 2 0 -0.0012 12 0 0 0 8.38E+07 1.97E+07 - - - 5.6406 0.9874 221125_WJC_METTL3_EV_vs_WT_F03.23547.23547.4 1.42E-08 25/126 Y.SALILHDDEVTVTEDKINALIK.A sp|P05386|RLA1_HUMAN 1 2436.3112 1.48 38052 23547 4 2436.305471 610.0851 60S acidic ribosomal protein P1 OS=Homo sapiens OX=9606 GN=RPLP1 PE=1 SV=1 4.43 3676.4 - 4.92E+06 - - - -2.3396 - 4.563 0.589 - 617.4 1 1 1 -0.0057 22 0 0 0 9.58E+07 6.46E+07 - - - 4.8478 1 221125_WJC_METTL3_EV_vs_WT_F03.23548.23548.3 3.40E-15 26/84 K.FVDGLMIHSGDPVNYYVDTAVR.H "sp|P23396|RS3_HUMAN,tr|H0YEU2|H0YEU2_HUMAN,tr|E9PSF4|E9PSF4_HUMAN,tr|E9PL09|E9PL09_HUMAN" 4 2467.1842 0.5 38053 23548 3 2467.180644 823.402 40S ribosomal protein S3 OS=Homo sapiens OX=9606 GN=RPS3 PE=1 SV=2 4.41 3676.5 - 4.81E+06 - - - -1.4397 - 3.843 0.723 - 584.5 1 2 0 -0.0036 22 0 0 0 6.61E+07 1.33E+08 - - - 9.7915 0.9984 221125_WJC_METTL3_EV_vs_WT_F03.23553.23553.3 7.34E-09 18/56 K.LIQLMEEIMAEKENK.T "sp|Q92841|DDX17_HUMAN,tr|A0A5H1ZRQ2|A0A5H1ZRQ2_HUMAN,tr|A0A1X7SBZ2|A0A1X7SBZ2_HUMAN" 3 1817.9267 1.33 38056 23553 3 1817.916383 606.9828 Probable ATP-dependent RNA helicase DDX17 OS=Homo sapiens OX=9606 GN=DDX17 PE=1 SV=2 4.49 3677.1 - 3.84E+06 - - - -5.6795 - 3.276 0.547 - 398.5 1 2 1 -0.0103 15 0 0 0 6.12E+07 4.60E+07 - - - 7.732 0.9999 221125_WJC_METTL3_EV_vs_WT_F03.23554.23554.4 2.99E-05 26/102 K.ISSIQSIVPALEIANAHR[166.11].K "sp|P10809|CH60_HUMAN,tr|A0A7I2V2X6|A0A7I2V2X6_HUMAN,tr|A0A7I2YQK6|A0A7I2YQK6_HUMAN,tr|A0A7I2V599|A0A7I2V599_HUMAN,tr|A0A7I2YQ71|A0A7I2YQ71_HUMAN,tr|A0A7I2V5M1|A0A7I2V5M1_HUMAN,tr|A0A7I2V5K3|A0A7I2V5K3_HUMAN,tr|A0A7I2V369|A0A7I2V369_HUMAN" 8 1928.0719 1.28 38057 23554 4 1928.067762 483.0252 "60 kDa heat shock protein, mitochondrial OS=Homo sapiens OX=9606 GN=HSPD1 PE=1 SV=2" 6.75 3677.1 - 1.77E+06 - - - -2.1358 - 3.703 0.47 - 730.9 1 2 0 -0.0041 18 0 0 0 8.37E+07 6.54E+07 - - - 3.7642 1 221125_WJC_METTL3_EV_vs_WT_F03.23555.23555.3 1.97E-08 21/76 K.VEDMAELTC[160.03]LNEASVLHNLK.D "sp|P35580|MYH10_HUMAN,sp|P35579|MYH9_HUMAN,tr|Q5BKV1|Q5BKV1_HUMAN,tr|E7ERA5|E7ERA5_HUMAN,tr|B1AH99|B1AH99_HUMAN" 5 2285.1032 0.52 38058 23555 3 2285.09086 762.7083 Myosin-10 OS=Homo sapiens OX=9606 GN=MYH10 PE=1 SV=3 4.4 3677.2 - 8.28E+06 - - - -5.3866 - 3.865 0.647 - 573.5 1 2 0 -0.0123 20 0 0 0 6.90E+07 1.33E+08 - - - 9.0299 0.9936 221125_WJC_METTL3_EV_vs_WT_F03.23556.23556.4 1.38E-09 28/126 Y.SALILHDDEVTVTEDK[136.11]INALIK[136.11].A sp|P05386|RLA1_HUMAN 1 2452.3396 1.48 38059 23556 4 2452.337971 614.0922 60S acidic ribosomal protein P1 OS=Homo sapiens OX=9606 GN=RPLP1 PE=1 SV=1 4.43 3677.2 - 4.88E+06 - - - -0.6524 - 5.395 0.593 - 641.2 1 1 1 -0.0016 22 0 0 0 9.58E+07 6.46E+07 - - - 4.9385 0.9855 221125_WJC_METTL3_EV_vs_WT_F03.23559.23559.3 0.000294 14/48 K.FNFGEEEFKFPPK.D "sp|Q92499|DDX1_HUMAN,tr|A0A7I2V2M5|A0A7I2V2M5_HUMAN,tr|A0A087X2G1|A0A087X2G1_HUMAN,tr|A0A7I2V430|A0A7I2V430_HUMAN,tr|A0A7I2V421|A0A7I2V421_HUMAN,tr|A0A7I2V4F0|A0A7I2V4F0_HUMAN,tr|A0A7I2V5X8|A0A7I2V5X8_HUMAN,tr|A0A7I2V4J3|A0A7I2V4J3_HUMAN,tr|A0A087WZ71|A0A087WZ71_HUMAN,tr|A0A7I2YQ77|A0A7I2YQ77_HUMAN" 10 1614.7718 2.75 38062 23559 3 1614.762571 539.2646 ATP-dependent RNA helicase DDX1 OS=Homo sapiens OX=9606 GN=DDX1 PE=1 SV=2 4.79 3677.6 - 875916 - - - -5.7432 - 2.185 0.393 - 128.6 1 2 1 -0.0093 13 0 0 0 2.08E+07 7.56E+06 - - - 5.0382 1 221125_WJC_METTL3_EV_vs_WT_F03.23562.23562.3 3.83E-13 22/88 K.AEIRYEGILYTIDTENSTVALAK.V "sp|Q8ND56|LS14A_HUMAN,tr|I3L4Q1|I3L4Q1_HUMAN,tr|A0A140TA76|A0A140TA76_HUMAN,tr|K7EMZ9|K7EMZ9_HUMAN" 4 2569.3275 0.91 38063 23562 3 2569.324669 857.4498 Protein LSM14 homolog A OS=Homo sapiens OX=9606 GN=LSM14A PE=1 SV=3 4.41 3678 - 9.90E+06 - - - -1.1209 - 4.031 0.685 - 413.2 1 2 1 -0.0029 23 0 0 0 3.08E+08 3.37E+08 - - - 9.4466 1 221125_WJC_METTL3_EV_vs_WT_F03.23563.23563.3 1.25E-09 27/84 Y.SALILHDDEVTVTEDK[136.11]INALIK[136.11].A sp|P05386|RLA1_HUMAN 1 2452.3396 3.46 38064 23563 3 2452.334963 818.4538 60S acidic ribosomal protein P1 OS=Homo sapiens OX=9606 GN=RPLP1 PE=1 SV=1 4.43 3678.1 - 3.47E+06 - - - -1.879 - 4.928 0.683 - 595.8 1 1 1 -0.0046 22 0 0 0 1.24E+08 3.58E+07 - - - 9.9348 1 221125_WJC_METTL3_EV_vs_WT_F03.23564.23564.2 2.65E-07 15/30 R.QLGQDLLNSYIENEGK[136.11].M "sp|O95757|HS74L_HUMAN,tr|E9PDE8|E9PDE8_HUMAN" 2 1827.9094 0.07 38065 23564 2 1827.907404 914.962 Heat shock 70 kDa protein 4L OS=Homo sapiens OX=9606 GN=HSPA4L PE=1 SV=3 4.14 3678.2 - 2.17E+06 - - - -1.0963 - 3.074 0.55 - 691.5 1 2 0 -0.002 16 0 0 0 6.30E+06 9.58E+07 - - - 5.8636 1 221125_WJC_METTL3_EV_vs_WT_F03.23568.23568.3 6.62E-12 25/88 K.AEIR[166.11]YEGILYTIDTENSTVALAK[136.11].V "sp|Q8ND56|LS14A_HUMAN,tr|I3L4Q1|I3L4Q1_HUMAN,tr|A0A140TA76|A0A140TA76_HUMAN,tr|K7EMZ9|K7EMZ9_HUMAN" 4 2587.35 0.91 38067 23568 3 2587.342988 863.4573 Protein LSM14 homolog A OS=Homo sapiens OX=9606 GN=LSM14A PE=1 SV=3 4.41 3678.8 - 1.62E+07 - - - -2.7175 - 4.979 0.633 - 760.5 1 2 1 -0.007 23 0 0 0 3.08E+08 3.37E+08 - - - 9.3612 1 221125_WJC_METTL3_EV_vs_WT_F03.23572.23572.2 1.12E-08 18/36 K.LENINGVTDGYLNSLC[160.03]TVR.A sp|P15924|DESP_HUMAN 1 2137.0474 999 38071 23572 2 2137.039414 1069.531 Desmoplakin OS=Homo sapiens OX=9606 GN=DSP PE=1 SV=3 4.37 3679.2 - 2.17E+06 - - - -3.722 - 3.529 0.625 - 835 1 2 0 -0.008 19 0 0 0 3.01E+07 0.00E+00 - - - 6.755 1 221125_WJC_METTL3_EV_vs_WT_F03.23577.23577.3 4.23E-11 16/52 K.EHVEPVFGFPQFVR.F sp|O75792|RNH2A_HUMAN 1 1686.8518 1.83 38074 23577 3 1686.852052 563.2912 Ribonuclease H2 subunit A OS=Homo sapiens OX=9606 GN=RNASEH2A PE=1 SV=2 5.4 3679.9 - 4.95E+06 - - - 0.1334 - 3.217 0.641 - 297.9 1 2 0 0.0002 14 0 0 0 1.40E+08 7.68E+07 - - - 8.7916 1 221125_WJC_METTL3_EV_vs_WT_F03.23578.23578.2 3.29E-10 18/32 R.AEGEWEDQEALDYFSDK.E "sp|Q9NYF8|BCLF1_HUMAN,tr|E9PKI6|E9PKI6_HUMAN,tr|A0A1W2PQ43|A0A1W2PQ43_HUMAN,tr|E9PK91|E9PK91_HUMAN,tr|E9PK09|E9PK09_HUMAN,tr|E9PQN2|E9PQN2_HUMAN" 6 2030.8381 11.62 38075 23578 2 2030.836895 1016.4263 Bcl-2-associated transcription factor 1 OS=Homo sapiens OX=9606 GN=BCLAF1 PE=1 SV=2 3.66 3680 - 3.25E+06 - - - -0.616 - 3.837 0.706 - 1353.1 1 2 0 -0.0013 17 0 0 0 3.85E+07 3.31E+06 - - - 7.5611 1 221125_WJC_METTL3_EV_vs_WT_F03.23579.23579.3 7.53E-14 26/108 R.ILLSQTTGVAIPLHASSLDDVSLASTPK.R sp|P12270|TPR_HUMAN 1 2833.5437 3.75 38076 23579 3 2833.543086 945.5218 Nucleoprotein TPR OS=Homo sapiens OX=9606 GN=TPR PE=1 SV=3 5.21 3680 - 8.56E+06 - - - -0.2132 - 4.933 0.688 - 512.1 1 2 0 -0.0006 28 0 0 0 9.54E+07 2.54E+07 - - - 9.8821 1 221125_WJC_METTL3_EV_vs_WT_F03.23580.23580.3 0.000187 17/68 K.NVDLLSDMVQEHDEPILK.H "sp|P55209|NP1L1_HUMAN,tr|F8VUX1|F8VUX1_HUMAN,tr|F8W543|F8W543_HUMAN,tr|F8W118|F8W118_HUMAN,tr|F8W0J6|F8W0J6_HUMAN,tr|F8VV59|F8VV59_HUMAN,tr|B7Z9C2|B7Z9C2_HUMAN,tr|F8VXI6|F8VXI6_HUMAN,tr|H0YHC3|H0YHC3_HUMAN,tr|H0YIV4|H0YIV4_HUMAN,tr|F5H4R6|F5H4R6_HUMAN,tr|H0YH88|H0YH88_HUMAN,tr|F8W020|F8W020_HUMAN,tr|F8VY35|F8VY35_HUMAN" 14 2094.0303 1.12 38077 23580 3 2094.025736 699.0174 Nucleosome assembly protein 1-like 1 OS=Homo sapiens OX=9606 GN=NAP1L1 PE=1 SV=1 4.1 3680.1 - 5.01E+06 - - - -2.1896 - 3.638 0.546 - 235.4 1 2 0 -0.0046 18 0 0 0 1.40E+08 1.25E+08 - - - 7.8419 1 221125_WJC_METTL3_EV_vs_WT_F03.23581.23581.3 1.21E-09 30/108 R.ILLSQTTGVAIPLHASSLDDVSLASTPK[136.11].R sp|P12270|TPR_HUMAN 1 2841.5579 3.75 38078 23581 3 2841.557249 948.1932 Nucleoprotein TPR OS=Homo sapiens OX=9606 GN=TPR PE=1 SV=3 5.21 3680.2 - 3.35E+06 - - - -0.2256 - 4.859 0.664 - 670.9 1 2 0 -0.0006 28 0 0 0 9.54E+07 2.54E+07 - - - 9.5797 1 221125_WJC_METTL3_EV_vs_WT_F03.23582.23582.3 2.00E-11 18/64 K.QVELALWDTAGQEDYDR.L "sp|P62745|RHOB_HUMAN,sp|P61586|RHOA_HUMAN,sp|P08134|RHOC_HUMAN,tr|U3KQA9|U3KQA9_HUMAN,tr|U3KQV3|U3KQV3_HUMAN,tr|E9PQH6|E9PQH6_HUMAN,tr|Q5JR06|Q5JR06_HUMAN,tr|C9JNR4|C9JNR4_HUMAN,tr|A0A7I2V3G1|A0A7I2V3G1_HUMAN,tr|Q5JR08|Q5JR08_HUMAN,tr|C9JX21|C9JX21_HUMAN,tr|Q5JR05|Q5JR05_HUMAN,tr|E9PN11|E9PN11_HUMAN,tr|Q5JR07|Q5JR07_HUMAN" 14 2007.9174 1.51 38079 23582 3 2007.915861 670.3131 Rho-related GTP-binding protein RhoB OS=Homo sapiens OX=9606 GN=RHOB PE=1 SV=1 3.77 3680.3 - 2.47E+06 - - - -0.7665 - 3.415 0.628 - 504 1 2 0 -0.0015 17 0 0 0 3.65E+07 2.42E+07 - - - 8.6439 0.9997 221125_WJC_METTL3_EV_vs_WT_F03.23583.23583.3 0.000402 20/52 R.TLTELILDAQEHVK.N "sp|P17480|UBF1_HUMAN,tr|E9PKP7|E9PKP7_HUMAN" 2 1608.8723 1.37 38080 23583 3 1608.871985 537.298 Nucleolar transcription factor 1 OS=Homo sapiens OX=9606 GN=UBTF PE=1 SV=1 4.65 3680.4 - 2.12E+06 - - - -0.1877 - 2.431 0.306 - 375.3 1 2 0 -0.0003 14 0 0 0 3.35E+07 2.44E+07 - - - 4.3122 0.9999 221125_WJC_METTL3_EV_vs_WT_F03.23584.23584.3 6.04E-09 18/64 K.QVELALWDTAGQEDYDR[166.11].L "sp|P62745|RHOB_HUMAN,sp|P61586|RHOA_HUMAN,sp|P08134|RHOC_HUMAN,tr|U3KQA9|U3KQA9_HUMAN,tr|U3KQV3|U3KQV3_HUMAN,tr|E9PQH6|E9PQH6_HUMAN,tr|Q5JR06|Q5JR06_HUMAN,tr|C9JNR4|C9JNR4_HUMAN,tr|A0A7I2V3G1|A0A7I2V3G1_HUMAN,tr|Q5JR08|Q5JR08_HUMAN,tr|C9JX21|C9JX21_HUMAN,tr|Q5JR05|Q5JR05_HUMAN,tr|E9PN11|E9PN11_HUMAN,tr|Q5JR07|Q5JR07_HUMAN" 14 2017.9257 1.51 38081 23584 3 2017.916742 673.6492 Rho-related GTP-binding protein RhoB OS=Homo sapiens OX=9606 GN=RHOB PE=1 SV=1 3.77 3680.6 - 1.89E+06 - - - -4.4243 - 3.211 0.595 - 474.4 1 2 0 -0.0089 17 0 0 0 3.65E+07 2.42E+07 - - - 8.1183 1 221125_WJC_METTL3_EV_vs_WT_F03.23585.23585.3 1.63E-08 14/48 K.C[160.03]EFQDAYVLLSEK.K "sp|P10809|CH60_HUMAN,tr|A0A7I2V2X6|A0A7I2V2X6_HUMAN,tr|A0A7I2YQK6|A0A7I2YQK6_HUMAN,tr|A0A7I2V599|A0A7I2V599_HUMAN,tr|A0A7I2YQ71|A0A7I2YQ71_HUMAN,tr|A0A7I2V5M1|A0A7I2V5M1_HUMAN,tr|A0A7I2V5K3|A0A7I2V5K3_HUMAN,tr|A0A7I2V369|A0A7I2V369_HUMAN" 8 1600.7443 1.31 38082 23585 3 1600.740635 534.5887 "60 kDa heat shock protein, mitochondrial OS=Homo sapiens OX=9606 GN=HSPD1 PE=1 SV=2" 4.14 3680.7 - 947029 - - - -2.2958 - 2.729 0.526 - 242.9 1 2 0 -0.0037 13 0 0 0 6.18E+07 4.70E+07 - - - 7.1253 0.9868 221125_WJC_METTL3_EV_vs_WT_F03.23587.23587.2 0.000758 14/18 V.PALEIANAHR[166.11].K "sp|P10809|CH60_HUMAN,tr|A0A7I2V2X6|A0A7I2V2X6_HUMAN,tr|A0A7I2YQK6|A0A7I2YQK6_HUMAN,tr|A0A7I2V599|A0A7I2V599_HUMAN,tr|A0A7I2YQ71|A0A7I2YQ71_HUMAN,tr|A0A7I2V5M1|A0A7I2V5M1_HUMAN,tr|A0A7I2V5K3|A0A7I2V5K3_HUMAN,tr|A0A7I2V369|A0A7I2V369_HUMAN" 8 1100.5966 1.16 38084 23587 2 1100.594888 551.3056 "60 kDa heat shock protein, mitochondrial OS=Homo sapiens OX=9606 GN=HSPD1 PE=1 SV=2" 7.18 3681 - 770957 - - - -1.5664 - 2.802 0.368 - 842.7 1 1 0 -0.0017 10 0 0 0 3.41E+07 2.96E+07 - - - 4.6345 0.9999 221125_WJC_METTL3_EV_vs_WT_F03.23590.23590.3 8.61E-07 18/76 K.K[136.11]LGGTIDDC[160.03]ELVEGLVLTQK[136.11].V sp|P50991|TCPD_HUMAN 1 2203.1741 0.39 38085 23590 3 2203.169358 735.3986 T-complex protein 1 subunit delta OS=Homo sapiens OX=9606 GN=CCT4 PE=1 SV=4 4.32 3681.4 - 1.01E+07 - - - -2.1455 - 2.901 0.477 - 467.5 1 2 0 -0.0047 20 0 0 0 8.46E+07 2.15E+08 - - - 6.4406 0.9998 221125_WJC_METTL3_EV_vs_WT_F03.23591.23591.3 1.51E-05 17/68 K.NVDLLSDMVQEHDEPILK[136.11].H "sp|P55209|NP1L1_HUMAN,tr|F8VUX1|F8VUX1_HUMAN,tr|F8W543|F8W543_HUMAN,tr|F8W118|F8W118_HUMAN,tr|F8W0J6|F8W0J6_HUMAN,tr|F8VV59|F8VV59_HUMAN,tr|B7Z9C2|B7Z9C2_HUMAN,tr|F8VXI6|F8VXI6_HUMAN,tr|H0YHC3|H0YHC3_HUMAN,tr|H0YIV4|H0YIV4_HUMAN,tr|F5H4R6|F5H4R6_HUMAN,tr|H0YH88|H0YH88_HUMAN,tr|F8W020|F8W020_HUMAN,tr|F8VY35|F8VY35_HUMAN" 14 2102.0445 1.2 38086 23591 3 2102.04008 701.6888 Nucleosome assembly protein 1-like 1 OS=Homo sapiens OX=9606 GN=NAP1L1 PE=1 SV=1 4.1 3681.4 - 1.01E+07 - - - -2.1127 - 2.762 0.357 - 239.6 1 2 0 -0.0044 18 0 0 0 1.51E+08 1.26E+08 - - - 5.0488 1 221125_WJC_METTL3_EV_vs_WT_F03.23592.23592.3 4.99E-10 19/60 K.K[136.11]VSQEILELLNTTTAK[136.11].E "sp|Q86U44|MTA70_HUMAN,tr|H0YFV6|H0YFV6_HUMAN" 2 1803.0324 0.01 38087 23592 3 1803.0279 602.0181 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 6.14 3681.4 - 5.51E+06 - - - -2.5124 - 4.005 0.645 - 695.1 1 2 0 -0.0045 16 0 0 0 2.80E+06 4.94E+08 - - - 9.2901 1 221125_WJC_METTL3_EV_vs_WT_F03.23593.23593.3 2.91E-07 16/52 K.EHVEPVFGFPQFVR[166.11].F sp|O75792|RNH2A_HUMAN 1 1696.8601 1.81 38088 23593 3 1696.859099 566.6273 Ribonuclease H2 subunit A OS=Homo sapiens OX=9606 GN=RNASEH2A PE=1 SV=2 5.4 3681.5 - 3.36E+06 - - - -0.5881 - 2.835 0.552 - 273 1 2 0 -0.001 14 0 0 0 1.39E+08 7.68E+07 - - - 7.4632 0.9841 221125_WJC_METTL3_EV_vs_WT_F03.23594.23594.3 0.0258 13/76 K.KLGGTIDDC[160.03]ELVEGLVLTQK.V sp|P50991|TCPD_HUMAN 1 2187.1457 0.39 38089 23594 3 2187.135986 730.0558 T-complex protein 1 subunit delta OS=Homo sapiens OX=9606 GN=CCT4 PE=1 SV=4 4.32 3681.6 - 3.11E+06 - - - -4.4345 - 2.324 0.219 - 180.4 1 2 0 -0.0097 20 0 0 0 8.46E+07 2.15E+08 - - - 3.0248 0.9999 221125_WJC_METTL3_EV_vs_WT_F03.23595.23595.3 0.00171 18/52 R.TLTELILDAQEHVK[136.11].N "sp|P17480|UBF1_HUMAN,tr|E9PKP7|E9PKP7_HUMAN" 2 1616.8865 1.37 38090 23595 3 1616.884163 539.9694 Nucleolar transcription factor 1 OS=Homo sapiens OX=9606 GN=UBTF PE=1 SV=1 4.65 3681.7 - 1.85E+06 - - - -1.4373 - 2.817 0.394 - 315.6 1 2 0 -0.0023 14 0 0 0 3.35E+07 2.44E+07 - - - 5.6844 0.9998 221125_WJC_METTL3_EV_vs_WT_F03.23599.23599.3 3.80E-07 Nov-48 K.C[160.03]EFQDAYVLLSEK[136.11].K "sp|P10809|CH60_HUMAN,tr|A0A7I2V2X6|A0A7I2V2X6_HUMAN,tr|A0A7I2YQK6|A0A7I2YQK6_HUMAN,tr|A0A7I2V599|A0A7I2V599_HUMAN,tr|A0A7I2YQ71|A0A7I2YQ71_HUMAN,tr|A0A7I2V5M1|A0A7I2V5M1_HUMAN,tr|A0A7I2V5K3|A0A7I2V5K3_HUMAN,tr|A0A7I2V369|A0A7I2V369_HUMAN" 8 1608.7585 1.32 38092 23599 3 1608.759712 537.2601 "60 kDa heat shock protein, mitochondrial OS=Homo sapiens OX=9606 GN=HSPD1 PE=1 SV=2" 4.14 3682.1 - 4.24E+06 - - - 0.7472 - 2.046 0.373 - 145.9 1 2 0 0.0012 13 0 0 0 6.16E+07 4.68E+07 - - - 4.6392 1 221125_WJC_METTL3_EV_vs_WT_F03.23602.23602.2 5.36E-10 18/32 K.QVELALWDTAGQEDYDR[166.11].L "sp|P62745|RHOB_HUMAN,sp|P61586|RHOA_HUMAN,sp|P08134|RHOC_HUMAN,tr|U3KQA9|U3KQA9_HUMAN,tr|U3KQV3|U3KQV3_HUMAN,tr|E9PQH6|E9PQH6_HUMAN,tr|Q5JR06|Q5JR06_HUMAN,tr|C9JNR4|C9JNR4_HUMAN,tr|A0A7I2V3G1|A0A7I2V3G1_HUMAN,tr|Q5JR08|Q5JR08_HUMAN,tr|C9JX21|C9JX21_HUMAN,tr|Q5JR05|Q5JR05_HUMAN,tr|E9PN11|E9PN11_HUMAN,tr|Q5JR07|Q5JR07_HUMAN" 14 2017.9257 1.1 38095 23602 2 2017.919328 1009.9701 Rho-related GTP-binding protein RhoB OS=Homo sapiens OX=9606 GN=RHOB PE=1 SV=1 3.77 3682.5 - 2.05E+06 - - - -3.1428 - 3.742 0.698 - 1275.2 1 2 0 -0.0063 17 0 0 0 2.37E+07 2.16E+07 - - - 7.4388 1 221125_WJC_METTL3_EV_vs_WT_F03.23604.23604.4 7.71E-07 18/96 R.LIDLHTNVATAVLEHIK[136.11].A "sp|Q8WVM8|SCFD1_HUMAN,tr|A0A7I2V4U2|A0A7I2V4U2_HUMAN,tr|A0A7I2V4B8|A0A7I2V4B8_HUMAN,tr|H0YIZ7|H0YIZ7_HUMAN,tr|A0A7I2V5Z4|A0A7I2V5Z4_HUMAN,tr|A0A7I2V3C9|A0A7I2V3C9_HUMAN,tr|B7Z5N7|B7Z5N7_HUMAN,tr|A0A7I2V5I2|A0A7I2V5I2_HUMAN,tr|A0A7I2V590|A0A7I2V590_HUMAN,tr|G3V5E2|G3V5E2_HUMAN,tr|A0A7I2V2U5|A0A7I2V2U5_HUMAN,tr|A0A7I2YQR2|A0A7I2YQR2_HUMAN,tr|A0A7I2V362|A0A7I2V362_HUMAN,tr|A0A7I2V448|A0A7I2V448_HUMAN,tr|A0A7I2V320|A0A7I2V320_HUMAN,tr|A0A7I2V3G4|A0A7I2V3G4_HUMAN,tr|A0A7I2V3B4|A0A7I2V3B4_HUMAN,tr|A0A7I2V5H5|A0A7I2V5H5_HUMAN,tr|A0A7I2V4R0|A0A7I2V4R0_HUMAN" 19 1894.0767 1.32 38097 23604 4 1894.074832 474.5265 Sec1 family domain-containing protein 1 OS=Homo sapiens OX=9606 GN=SCFD1 PE=1 SV=4 5.99 3682.8 - 1.74E+06 - - - -1.0116 - 2.85 0.578 - 256.9 1 2 0 -0.0019 17 0 0 0 2.65E+07 2.00E+07 - - - 4.62 1 221125_WJC_METTL3_EV_vs_WT_F03.23606.23606.2 2.29E-11 17/32 K.DSSFIVVNTQSLPVTVK[136.11].S sp|Q5T3J3|LRIF1_HUMAN 1 1841.0026 1.7 38099 23606 2 1840.998045 921.5086 Ligand-dependent nuclear receptor-interacting factor 1 OS=Homo sapiens OX=9606 GN=LRIF1 PE=1 SV=1 5.84 3683.1 - 1.15E+06 - - - -2.4633 - 2.85 0.601 - 742.5 1 2 0 -0.0045 17 0 0 0 1.76E+07 1.03E+07 - - - 6.0534 0.9979 221125_WJC_METTL3_EV_vs_WT_F03.23609.23609.3 7.80E-07 14/64 L.NLTTDNANILLQIDNAR.L "sp|P13645|K1C10_HUMAN,tr|A0A1B0GVI3|A0A1B0GVI3_HUMAN" 2 1897.9858 55.18 38100 23609 3 1897.985541 633.6692 "Keratin, type I cytoskeletal 10 OS=Homo sapiens OX=9606 GN=KRT10 PE=1 SV=6" 4.21 3683.4 - 6.19E+06 - - - -0.1122 - 2.676 0.541 - 279.4 1 1 0 -0.0002 17 0 0 0 1.29E+08 2.35E+06 - - - 7.0583 0.9999 221125_WJC_METTL3_EV_vs_WT_F03.23610.23610.3 7.71E-08 17/60 R.QLGQDLLNSYIENEGK[136.11].M "sp|O95757|HS74L_HUMAN,tr|E9PDE8|E9PDE8_HUMAN" 2 1827.9094 0 38101 23610 3 1827.903742 610.3104 Heat shock 70 kDa protein 4L OS=Homo sapiens OX=9606 GN=HSPA4L PE=1 SV=3 4.14 3683.5 - 4.38E+06 - - - -3.0997 - 3.017 0.575 - 415.4 1 2 0 -0.0057 16 0 0 0 1.98E+05 4.37E+07 - - - 7.7825 1 221125_WJC_METTL3_EV_vs_WT_F03.23611.23611.2 4.23E-08 13/24 K.C[160.03]EFQDAYVLLSEK.K "sp|P10809|CH60_HUMAN,tr|A0A7I2V2X6|A0A7I2V2X6_HUMAN,tr|A0A7I2YQK6|A0A7I2YQK6_HUMAN,tr|A0A7I2V599|A0A7I2V599_HUMAN,tr|A0A7I2YQ71|A0A7I2YQ71_HUMAN,tr|A0A7I2V5M1|A0A7I2V5M1_HUMAN,tr|A0A7I2V5K3|A0A7I2V5K3_HUMAN,tr|A0A7I2V369|A0A7I2V369_HUMAN" 8 1600.7443 1.22 38102 23611 2 1600.742705 801.3794 "60 kDa heat shock protein, mitochondrial OS=Homo sapiens OX=9606 GN=HSPD1 PE=1 SV=2" 4.14 3683.5 - 1.05E+07 - - - -1.0027 - 2.623 0.664 - 479.9 1 2 0 -0.0016 13 0 0 0 1.36E+08 1.11E+08 - - - 6.4198 1 221125_WJC_METTL3_EV_vs_WT_F03.23612.23612.2 1.33E-13 23/32 L.NLTTDNANILLQIDNAR.L "sp|P13645|K1C10_HUMAN,tr|A0A1B0GVI3|A0A1B0GVI3_HUMAN" 2 1897.9858 999 38103 23612 2 1897.984516 950.0002 "Keratin, type I cytoskeletal 10 OS=Homo sapiens OX=9606 GN=KRT10 PE=1 SV=6" 4.21 3683.6 - 3.78E+06 - - - -0.6523 - 4.171 0.684 - 2120 1 1 0 -0.0012 17 0 0 0 6.87E+07 0.00E+00 - - - 7.6038 0.9999 221125_WJC_METTL3_EV_vs_WT_F03.23614.23614.3 3.70E-06 18/60 R.SAQPLPLKIEELALAK.G "sp|Q9UKV3|ACINU_HUMAN,tr|S4R3H4|S4R3H4_HUMAN,tr|E7EQT4|E7EQT4_HUMAN" 3 1720.0135 1.55 38105 23614 3 1720.015917 574.3451 Apoptotic chromatin condensation inducer in the nucleus OS=Homo sapiens OX=9606 GN=ACIN1 PE=1 SV=2 5.86 3683.9 - 1.97E+06 - - - 1.4215 - 3.033 0.529 - 373.1 1 2 1 0.0024 16 0 0 0 3.63E+07 2.34E+07 - - - 7.2841 0.9997 221125_WJC_METTL3_EV_vs_WT_F03.23615.23615.3 8.27E-07 20/56 K.MFEIVFEDPK[136.11]IPGEK[136.11].Q sp|P07814|SYEP_HUMAN 1 1793.9245 0.91 38106 23615 3 1793.925332 598.9821 Bifunctional glutamate\proline--tRNA ligase OS=Homo sapiens OX=9606 GN=EPRS1 PE=1 SV=5 4.41 3684 - 1.44E+06 - - - 0.4866 - 3.02 0.385 - 533.2 1 2 1 0.0009 15 0 0 0 2.73E+07 3.01E+07 - - - 5.7161 1 221125_WJC_METTL3_EV_vs_WT_F03.23616.23616.2 9.29E-09 16/30 R.QLGQDLLNSYIENEGK.M "sp|O95757|HS74L_HUMAN,tr|E9PDE8|E9PDE8_HUMAN" 2 1819.8952 0.07 38107 23616 2 1819.895903 910.9549 Heat shock 70 kDa protein 4L OS=Homo sapiens OX=9606 GN=HSPA4L PE=1 SV=3 4.14 3684.2 - 866268 - - - 0.3819 - 2.901 0.631 - 535.7 1 2 0 0.0007 16 0 0 0 6.30E+06 9.49E+07 - - - 6.3198 0.9999 221125_WJC_METTL3_EV_vs_WT_F03.23617.23617.3 0.0192 16/68 K.MSPDEGQEELEEVQAELK[136.11].K "sp|Q9HC07|TM165_HUMAN,tr|V9GY93|V9GY93_HUMAN" 2 2067.9398 1.07 38108 23617 3 2067.935253 690.3205 Transmembrane protein 165 OS=Homo sapiens OX=9606 GN=TMEM165 PE=1 SV=1 3.77 3684.3 - 1.46E+06 - - - -2.1896 - 2.786 0.411 - 296.2 1 2 0 -0.0045 18 0 0 0 1.07E+07 9.97E+06 - - - 5.6724 0.9999 221125_WJC_METTL3_EV_vs_WT_F03.23620.23620.4 6.55E-06 16/96 R.LIDLHTNVATAVLEHIK.A "sp|Q8WVM8|SCFD1_HUMAN,tr|A0A7I2V4U2|A0A7I2V4U2_HUMAN,tr|A0A7I2V4B8|A0A7I2V4B8_HUMAN,tr|H0YIZ7|H0YIZ7_HUMAN,tr|A0A7I2V5Z4|A0A7I2V5Z4_HUMAN,tr|A0A7I2V3C9|A0A7I2V3C9_HUMAN,tr|B7Z5N7|B7Z5N7_HUMAN,tr|A0A7I2V5I2|A0A7I2V5I2_HUMAN,tr|A0A7I2V590|A0A7I2V590_HUMAN,tr|G3V5E2|G3V5E2_HUMAN,tr|A0A7I2V2U5|A0A7I2V2U5_HUMAN,tr|A0A7I2YQR2|A0A7I2YQR2_HUMAN,tr|A0A7I2V362|A0A7I2V362_HUMAN,tr|A0A7I2V448|A0A7I2V448_HUMAN,tr|A0A7I2V320|A0A7I2V320_HUMAN,tr|A0A7I2V3G4|A0A7I2V3G4_HUMAN,tr|A0A7I2V3B4|A0A7I2V3B4_HUMAN,tr|A0A7I2V5H5|A0A7I2V5H5_HUMAN,tr|A0A7I2V4R0|A0A7I2V4R0_HUMAN" 19 1886.0625 1.32 38109 23620 4 1886.058735 472.5229 Sec1 family domain-containing protein 1 OS=Homo sapiens OX=9606 GN=SCFD1 PE=1 SV=4 5.99 3684.7 - 2.76E+06 - - - -2.0217 - 2.79 0.488 - 214 1 2 0 -0.0038 17 0 0 0 2.65E+07 2.00E+07 - - - 3.8287 1 221125_WJC_METTL3_EV_vs_WT_F03.23622.23622.3 5.35E-09 21/100 K.EGPYDVVVLPGGNLGAQNLSESAAVK.E "sp|Q99497|PARK7_HUMAN,tr|K7EN27|K7EN27_HUMAN" 2 2583.318 2.45 38111 23622 3 2583.316284 862.1133 Parkinson disease protein 7 OS=Homo sapiens OX=9606 GN=PARK7 PE=1 SV=2 4.14 3684.8 - 1.22E+07 - - - -0.6825 - 3.617 0.598 - 477.8 1 2 0 -0.0018 26 0 0 0 4.10E+08 1.67E+08 - - - 8.1644 1 221125_WJC_METTL3_EV_vs_WT_F03.23623.23623.2 6.79E-08 24-Dec K.C[160.03]EFQDAYVLLSEK[136.11].K "sp|P10809|CH60_HUMAN,tr|A0A7I2V2X6|A0A7I2V2X6_HUMAN,tr|A0A7I2YQK6|A0A7I2YQK6_HUMAN,tr|A0A7I2V599|A0A7I2V599_HUMAN,tr|A0A7I2YQ71|A0A7I2YQ71_HUMAN,tr|A0A7I2V5M1|A0A7I2V5M1_HUMAN,tr|A0A7I2V5K3|A0A7I2V5K3_HUMAN,tr|A0A7I2V369|A0A7I2V369_HUMAN" 8 1608.7585 1.23 38112 23623 2 1608.755511 805.3865 "60 kDa heat shock protein, mitochondrial OS=Homo sapiens OX=9606 GN=HSPD1 PE=1 SV=2" 4.14 3684.9 - 7.89E+06 - - - -1.8642 - 2.498 0.598 - 369.4 1 2 0 -0.003 13 0 0 0 1.36E+08 1.11E+08 - - - 5.8065 1 221125_WJC_METTL3_EV_vs_WT_F03.23625.23625.2 9.27E-10 26/30 K.K[136.11]VSQEILELLNTTTAK[136.11].E "sp|Q86U44|MTA70_HUMAN,tr|H0YFV6|H0YFV6_HUMAN" 2 1803.0324 0.001 38114 23625 2 1803.027044 902.5235 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 6.14 3685.1 - 3.43E+06 - - - -2.9872 - 4.262 0.631 - 2191.9 1 2 0 -0.0054 16 0 0 0 0.00E+00 7.08E+07 - - - 7.2641 1 221125_WJC_METTL3_EV_vs_WT_F03.23626.23626.3 1.57E-09 20/76 K.IASWADLVNAHVVPGSGVVK[136.11].G sp|P11172|UMPS_HUMAN 1 2026.1091 1.02 38115 23626 3 2026.107888 676.377 Uridine 5'-monophosphate synthase OS=Homo sapiens OX=9606 GN=UMPS PE=1 SV=1 6.74 3685.2 - 2.20E+06 - - - -0.6036 - 3.82 0.558 - 409.1 1 2 0 -0.0012 20 0 0 0 3.24E+07 3.18E+07 - - - 8.0123 0.9977 221125_WJC_METTL3_EV_vs_WT_F03.23627.23627.3 9.13E-06 13/68 K.VSVPSNLSYGEWLHGFEK[136.11].K "sp|Q86UP2|KTN1_HUMAN,tr|B7Z6P3|B7Z6P3_HUMAN,tr|G3V5P0|G3V5P0_HUMAN,tr|G3V4Y7|G3V4Y7_HUMAN" 4 2056.0145 1.81 38116 23627 3 2056.000163 686.3455 Kinectin OS=Homo sapiens OX=9606 GN=KTN1 PE=1 SV=1 5.4 3685.2 - 1.93E+06 - - - -6.9931 - 2.616 0.48 - 93.9 1 2 0 -0.0144 18 0 0 0 2.27E+07 1.26E+07 - - - 6.2821 1 221125_WJC_METTL3_EV_vs_WT_F03.23629.23629.3 2.91E-08 16/76 K.IASWADLVNAHVVPGSGVVK.G sp|P11172|UMPS_HUMAN 1 2018.0949 1.02 38118 23629 3 2018.091358 673.7056 Uridine 5'-monophosphate synthase OS=Homo sapiens OX=9606 GN=UMPS PE=1 SV=1 6.74 3685.4 - 1.80E+06 - - - -1.7606 - 2.996 0.584 - 223.8 1 2 0 -0.0036 20 0 0 0 3.24E+07 3.18E+07 - - - 7.7121 0.9953 221125_WJC_METTL3_EV_vs_WT_F03.23630.23630.3 1.64E-05 15/52 K.VK[136.11]DTFNGNLPFLFK[136.11].V "sp|P34949|MPI_HUMAN,tr|H3BPB8|H3BPB8_HUMAN,tr|H3BP57|H3BP57_HUMAN,tr|H3BT48|H3BT48_HUMAN,tr|H3BPU7|H3BPU7_HUMAN,tr|H3BQX0|H3BQX0_HUMAN,tr|H3BUZ9|H3BUZ9_HUMAN,tr|H3BT46|H3BT46_HUMAN,tr|H3BPM5|H3BPM5_HUMAN,tr|B4DYB8|B4DYB8_HUMAN,tr|H3BPP3|H3BPP3_HUMAN,tr|H3BN01|H3BN01_HUMAN,tr|F5GX71|F5GX71_HUMAN,tr|H3BMZ9|H3BMZ9_HUMAN,tr|H3BNY8|H3BNY8_HUMAN" 15 1654.9054 1.34 38119 23630 3 1654.905459 552.6424 Mannose-6-phosphate isomerase OS=Homo sapiens OX=9606 GN=MPI PE=1 SV=2 8.56 3685.5 - 1.05E+06 - - - 0.0483 - 2.216 0.237 - 257.7 1 2 1 0.0001 14 0 0 0 3.28E+07 2.44E+07 - - - 3.2969 1 221125_WJC_METTL3_EV_vs_WT_F03.23631.23631.2 9.29E-16 20/36 R.LSQEQVDNFTLDINTAYAR[166.11].L "sp|Q16891|MIC60_HUMAN,tr|B9A067|B9A067_HUMAN,tr|C9J406|C9J406_HUMAN,tr|H7C463|H7C463_HUMAN" 4 2207.0734 1.56 38120 23631 2 2207.064864 1104.544 MICOS complex subunit MIC60 OS=Homo sapiens OX=9606 GN=IMMT PE=1 SV=1 4.03 3685.6 - 943197 - - - -3.8662 - 4.154 0.681 - 1418.7 1 2 0 -0.0085 19 0 0 0 3.01E+07 1.93E+07 - - - 7.5693 1 221125_WJC_METTL3_EV_vs_WT_F03.23632.23632.2 6.75E-06 16/32 K.QVELALWDTAGQEDYDR.L "sp|P62745|RHOB_HUMAN,sp|P61586|RHOA_HUMAN,sp|P08134|RHOC_HUMAN,tr|U3KQA9|U3KQA9_HUMAN,tr|U3KQV3|U3KQV3_HUMAN,tr|E9PQH6|E9PQH6_HUMAN,tr|Q5JR06|Q5JR06_HUMAN,tr|C9JNR4|C9JNR4_HUMAN,tr|A0A7I2V3G1|A0A7I2V3G1_HUMAN,tr|Q5JR08|Q5JR08_HUMAN,tr|C9JX21|C9JX21_HUMAN,tr|Q5JR05|Q5JR05_HUMAN,tr|E9PN11|E9PN11_HUMAN,tr|Q5JR07|Q5JR07_HUMAN" 14 2007.9174 1.1 38121 23632 2 2007.917912 1004.966 Rho-related GTP-binding protein RhoB OS=Homo sapiens OX=9606 GN=RHOB PE=1 SV=1 3.77 3685.8 - 910407 - - - 0.255 - 3.54 0.668 - 817.1 1 2 0 0.0005 17 0 0 0 2.37E+07 2.16E+07 - - - 7.0826 0.9996 221125_WJC_METTL3_EV_vs_WT_F03.23634.23634.3 9.72E-07 13/40 K.GKFDVQWIFVK.D sp|Q9BYJ9|YTHD1_HUMAN 1 1365.7445 1.72 38123 23634 3 1365.740925 456.2554 YTH domain-containing family protein 1 OS=Homo sapiens OX=9606 GN=YTHDF1 PE=1 SV=1 8.59 3686 - 567099 - - - -2.6235 - 2.483 0.485 - 343.3 1 2 1 -0.0036 11 0 0 0 1.29E+07 7.49E+06 - - - 6.5299 1 221125_WJC_METTL3_EV_vs_WT_F03.23637.23637.3 3.77E-08 20/68 K.ISSIQSIVPALEIANAHR.K "sp|P10809|CH60_HUMAN,tr|A0A7I2V2X6|A0A7I2V2X6_HUMAN,tr|A0A7I2YQK6|A0A7I2YQK6_HUMAN,tr|A0A7I2V599|A0A7I2V599_HUMAN,tr|A0A7I2YQ71|A0A7I2YQ71_HUMAN,tr|A0A7I2V5M1|A0A7I2V5M1_HUMAN,tr|A0A7I2V5K3|A0A7I2V5K3_HUMAN,tr|A0A7I2V369|A0A7I2V369_HUMAN" 8 1918.0636 1.33 38125 23637 3 1918.062393 640.3618 "60 kDa heat shock protein, mitochondrial OS=Homo sapiens OX=9606 GN=HSPD1 PE=1 SV=2" 6.75 3686.4 - 1.50E+08 - - - -0.6345 - 3.447 0.572 - 371.3 1 2 0 -0.0012 18 0 0 0 2.01E+10 1.51E+10 - - - 7.9984 1 221125_WJC_METTL3_EV_vs_WT_F03.23639.23639.3 4.64E-15 31/96 R.YNFPNPNPFVEDDMDKNEIASVAYR.Y sp|O15371|EIF3D_HUMAN 1 2944.3338 1.06 38126 23639 3 2944.336346 982.4519 Eukaryotic translation initiation factor 3 subunit D OS=Homo sapiens OX=9606 GN=EIF3D PE=1 SV=1 4.11 3686.6 - 3.60E+06 - - - 0.8739 - 5.054 0.75 - 813.9 1 2 1 0.0026 25 0 0 0 4.18E+07 3.93E+07 - - - 10.6285 0.9791 221125_WJC_METTL3_EV_vs_WT_F03.23640.23640.3 0.164 14/52 K.VKDTFNGNLPFLFK.V "sp|P34949|MPI_HUMAN,tr|H3BPB8|H3BPB8_HUMAN,tr|H3BP57|H3BP57_HUMAN,tr|H3BT48|H3BT48_HUMAN,tr|H3BPU7|H3BPU7_HUMAN,tr|H3BQX0|H3BQX0_HUMAN,tr|H3BUZ9|H3BUZ9_HUMAN,tr|H3BT46|H3BT46_HUMAN,tr|H3BPM5|H3BPM5_HUMAN,tr|B4DYB8|B4DYB8_HUMAN,tr|H3BPP3|H3BPP3_HUMAN,tr|H3BN01|H3BN01_HUMAN,tr|F5GX71|F5GX71_HUMAN,tr|H3BMZ9|H3BMZ9_HUMAN,tr|H3BNY8|H3BNY8_HUMAN" 15 1638.877 1.34 38127 23640 3 1638.876814 547.2996 Mannose-6-phosphate isomerase OS=Homo sapiens OX=9606 GN=MPI PE=1 SV=2 8.56 3686.7 - 2.94E+06 - - - -0.1007 - 1.971 0.174 - 241.4 1 2 1 -0.0002 14 0 0 0 3.28E+07 2.44E+07 - - - 2.2831 1 221125_WJC_METTL3_EV_vs_WT_F03.23642.23642.3 3.07E-11 19/84 R.GEVPC[160.03]TVTSASPLEEATLSELK.T "sp|P48047|ATPO_HUMAN,tr|H7C068|H7C068_HUMAN" 2 2317.1359 1.41 38129 23642 3 2317.136779 773.3859 "ATP synthase subunit O, mitochondrial OS=Homo sapiens OX=9606 GN=ATP5PO PE=1 SV=1" 4.09 3686.8 - 2.59E+06 - - - 0.3755 - 3.74 0.65 - 452.8 1 2 0 0.0009 22 0 0 0 1.06E+08 7.48E+07 - - - 8.9139 0.9998 221125_WJC_METTL3_EV_vs_WT_F03.23643.23643.3 0.00097 16/56 K.MFEIVFEDPKIPGEK.Q sp|P07814|SYEP_HUMAN 1 1777.8961 0.96 38130 23643 3 1777.897881 593.6393 Bifunctional glutamate\proline--tRNA ligase OS=Homo sapiens OX=9606 GN=EPRS1 PE=1 SV=5 4.41 3686.8 - 2.58E+06 - - - 1.0248 - 2.592 0.481 - 286.3 1 2 1 0.0018 15 0 0 0 2.88E+07 3.01E+07 - - - 6.3874 1 221125_WJC_METTL3_EV_vs_WT_F03.23644.23644.2 2.29E-14 20/36 R.LSQEQVDNFTLDINTAYAR.L "sp|Q16891|MIC60_HUMAN,tr|B9A067|B9A067_HUMAN,tr|C9J406|C9J406_HUMAN,tr|H7C463|H7C463_HUMAN" 4 2197.0651 1.56 38131 23644 2 2197.06368 1099.5398 MICOS complex subunit MIC60 OS=Homo sapiens OX=9606 GN=IMMT PE=1 SV=1 4.03 3687 - 2.56E+06 - - - -0.6586 - 4.056 0.635 - 1371.6 1 2 0 -0.0014 19 0 0 0 3.01E+07 1.93E+07 - - - 7.1731 0.9998 221125_WJC_METTL3_EV_vs_WT_F03.23646.23646.3 8.40E-06 13/64 R.QALDK[136.11]LNGFQLENFTLK[136.11].V sp|O00425|IF2B3_HUMAN 1 1994.0808 1.69 38133 23646 3 1994.083488 665.7009 Insulin-like growth factor 2 mRNA-binding protein 3 OS=Homo sapiens OX=9606 GN=IGF2BP3 PE=1 SV=2 6.07 3687.2 - 1.96E+06 - - - 1.3595 - 2.77 0.476 - 255.5 1 2 1 0.0027 17 0 0 0 1.73E+07 1.03E+07 - - - 6.4201 0.9999 221125_WJC_METTL3_EV_vs_WT_F03.23647.23647.2 1.16E-07 13/26 R.GLGWVQFSSEEGLR.N "sp|Q9GZT3|SLIRP_HUMAN,tr|H0YJW7|H0YJW7_HUMAN,tr|A0A087WUN7|A0A087WUN7_HUMAN,tr|G3V2S9|G3V2S9_HUMAN,tr|H0YJ40|H0YJ40_HUMAN,tr|G3V4X6|G3V4X6_HUMAN" 6 1563.7682 1.24 38134 23647 2 1563.766615 782.8914 "SRA stem-loop-interacting RNA-binding protein, mitochondrial OS=Homo sapiens OX=9606 GN=SLIRP PE=1 SV=1" 4.53 3687.3 - 1.26E+06 - - - -0.9861 - 2.702 0.56 - 519.6 1 2 0 -0.0015 14 0 0 0 1.35E+07 1.08E+07 - - - 5.671 0.9997 221125_WJC_METTL3_EV_vs_WT_F03.23649.23649.3 0.000137 Dec-40 K.GK[136.11]FDVQWIFVK[136.11].D sp|Q9BYJ9|YTHD1_HUMAN 1 1381.7729 1.71 38136 23649 3 1381.772132 461.5982 YTH domain-containing family protein 1 OS=Homo sapiens OX=9606 GN=YTHDF1 PE=1 SV=1 8.59 3687.6 - 798653 - - - -0.5616 - 2.315 0.426 - 293.2 1 2 1 -0.0008 11 0 0 0 1.28E+07 7.49E+06 - - - 5.6739 1 221125_WJC_METTL3_EV_vs_WT_F03.23650.23650.4 5.75E-09 21/96 M.PSQMEHAMETMMFTFHK.F sp|P60903|S10AA_HUMAN 1 2081.8831 2.02 38137 23650 4 2081.885567 521.4781 Protein S100-A10 OS=Homo sapiens OX=9606 GN=S100A10 PE=1 SV=2 6.02 3687.7 - 761360 - - - 1.1634 - 3.981 0.629 - 491.1 1 2 0 0.0024 17 0 0 0 6.47E+06 3.20E+06 - - - 5.1798 0.9998 221125_WJC_METTL3_EV_vs_WT_F03.23651.23651.3 0.00152 Dec-60 K.DTIIDVVGAPLTPNSR.K sp|Q9NPF5|DMAP1_HUMAN 1 1666.889 1.17 38138 23651 3 1666.890316 556.6369 DNA methyltransferase 1-associated protein 1 OS=Homo sapiens OX=9606 GN=DMAP1 PE=1 SV=1 4.21 3687.8 - 692523 - - - 0.7895 - 2.303 0.344 - 132.3 1 2 0 0.0013 16 0 0 0 1.14E+07 9.73E+06 - - - 4.5154 0.9999 221125_WJC_METTL3_EV_vs_WT_F03.23652.23652.2 5.09E-08 13/32 K.DSSFIVVNTQSLPVTVK.S sp|Q5T3J3|LRIF1_HUMAN 1 1832.9884 1.7 38139 23652 2 1832.989478 917.5015 Ligand-dependent nuclear receptor-interacting factor 1 OS=Homo sapiens OX=9606 GN=LRIF1 PE=1 SV=1 5.84 3687.9 - 491553 - - - 0.599 - 2.36 0.516 - 252.8 1 2 0 0.0011 17 0 0 0 1.76E+07 1.03E+07 - - - 4.9629 1 221125_WJC_METTL3_EV_vs_WT_F03.23653.23653.2 1.65E-10 15/28 R.GLDEDETNFLDEVSR[166.11].Q "sp|Q9GZU8|PIP30_HUMAN,tr|H3BP64|H3BP64_HUMAN,tr|H3BTP8|H3BTP8_HUMAN,tr|H3BMX9|H3BMX9_HUMAN,tr|H3BQQ6|H3BQQ6_HUMAN,tr|H3BU93|H3BU93_HUMAN,tr|H3BTI2|H3BTI2_HUMAN,tr|H3BUL4|H3BUL4_HUMAN,tr|H3BSY6|H3BSY6_HUMAN" 9 1747.7776 0.001 38140 23653 2 1747.774532 874.8961 PSME3-interacting protein OS=Homo sapiens OX=9606 GN=PSME3IP1 PE=1 SV=1 3.71 3688.1 - 464825 - - - -1.7599 - 3.308 0.611 - 887.2 1 2 0 -0.0031 15 0 0 0 0.00E+00 2.99E+06 - - - 6.4941 1 221125_WJC_METTL3_EV_vs_WT_F03.23655.23655.3 1.31E-08 18/68 K.ISSIQSIVPALEIANAHR[166.11].K "sp|P10809|CH60_HUMAN,tr|A0A7I2V2X6|A0A7I2V2X6_HUMAN,tr|A0A7I2YQK6|A0A7I2YQK6_HUMAN,tr|A0A7I2V599|A0A7I2V599_HUMAN,tr|A0A7I2YQ71|A0A7I2YQ71_HUMAN,tr|A0A7I2V5M1|A0A7I2V5M1_HUMAN,tr|A0A7I2V5K3|A0A7I2V5K3_HUMAN,tr|A0A7I2V369|A0A7I2V369_HUMAN" 8 1928.0719 1.33 38141 23655 3 1928.070073 643.6979 "60 kDa heat shock protein, mitochondrial OS=Homo sapiens OX=9606 GN=HSPD1 PE=1 SV=2" 6.75 3688.3 - 3.54E+07 - - - -0.9372 - 3.111 0.584 - 376.3 1 2 0 -0.0018 18 0 0 0 2.01E+10 1.51E+10 - - - 7.8766 1 221125_WJC_METTL3_EV_vs_WT_F03.23657.23657.3 5.18E-09 20/72 R.LSQEQVDNFTLDINTAYAR.L "sp|Q16891|MIC60_HUMAN,tr|B9A067|B9A067_HUMAN,tr|C9J406|C9J406_HUMAN,tr|H7C463|H7C463_HUMAN" 4 2197.0651 1.47 38142 23657 3 2197.065102 733.3623 MICOS complex subunit MIC60 OS=Homo sapiens OX=9606 GN=IMMT PE=1 SV=1 4.03 3688.5 - 1.33E+07 - - - -0.0114 - 3.651 0.585 - 536.2 1 2 0 0 19 0 0 0 1.01E+08 6.87E+07 - - - 8.2437 0.9999 221125_WJC_METTL3_EV_vs_WT_F03.23658.23658.4 8.31E-06 20/120 K.LFIGGLSFETTDDSLR[166.11]EHFEK[136.11].W "sp|P51991|ROA3_HUMAN,tr|A0A7I2V5D8|A0A7I2V5D8_HUMAN,tr|A0A7I2V2R3|A0A7I2V2R3_HUMAN,tr|A0A7I2V4J6|A0A7I2V4J6_HUMAN,tr|A0A7I2V4G0|A0A7I2V4G0_HUMAN,tr|A0A7I2V402|A0A7I2V402_HUMAN" 6 2458.2135 1.32 38143 23658 4 2458.214004 615.5607 Heterogeneous nuclear ribonucleoprotein A3 OS=Homo sapiens OX=9606 GN=HNRNPA3 PE=1 SV=2 4.5 3688.6 - 3.36E+06 - - - 0.1949 - 3.86 0.493 - 205.2 1 2 1 0.0005 21 0 0 0 6.98E+07 5.28E+07 - - - 3.9635 1 221125_WJC_METTL3_EV_vs_WT_F03.23659.23659.3 2.82E-09 20/72 R.LSQEQVDNFTLDINTAYAR[166.11].L "sp|Q16891|MIC60_HUMAN,tr|B9A067|B9A067_HUMAN,tr|C9J406|C9J406_HUMAN,tr|H7C463|H7C463_HUMAN" 4 2207.0734 1.47 38144 23659 3 2207.072858 736.6984 MICOS complex subunit MIC60 OS=Homo sapiens OX=9606 GN=IMMT PE=1 SV=1 4.03 3688.6 - 9.03E+06 - - - -0.2442 - 3.752 0.603 - 546.4 1 2 0 -0.0005 19 0 0 0 1.01E+08 6.87E+07 - - - 8.5113 1 221125_WJC_METTL3_EV_vs_WT_F03.23660.23660.3 0.000496 14/48 K.KQFEELTLGEFLK.L "sp|O15392|BIRC5_HUMAN,tr|A0A0B4J1S3|A0A0B4J1S3_HUMAN,tr|K7EMW2|K7EMW2_HUMAN,tr|H3BLT4|H3BLT4_HUMAN" 4 1580.845 1.95 38145 23660 3 1580.845261 527.9556 Baculoviral IAP repeat-containing protein 5 OS=Homo sapiens OX=9606 GN=BIRC5 PE=1 SV=3 4.79 3688.7 - 3.43E+06 - - - 0.1588 - 2.957 0.499 - 328 1 2 0 0.0003 13 0 0 0 6.63E+07 3.41E+07 - - - 7.0428 1 221125_WJC_METTL3_EV_vs_WT_F03.23661.23661.3 0.000289 15/48 K.K[136.11]QFEELTLGEFLK[136.11].L "sp|O15392|BIRC5_HUMAN,tr|A0A0B4J1S3|A0A0B4J1S3_HUMAN,tr|K7EMW2|K7EMW2_HUMAN,tr|H3BLT4|H3BLT4_HUMAN" 4 1596.8734 1.96 38146 23661 3 1596.87346 533.2984 Baculoviral IAP repeat-containing protein 5 OS=Homo sapiens OX=9606 GN=BIRC5 PE=1 SV=3 4.79 3688.7 - 2.58E+06 - - - 0.0313 - 2.658 0.488 - 400.4 1 2 0 0.0001 13 0 0 0 6.63E+07 3.39E+07 - - - 6.6312 0.9999 221125_WJC_METTL3_EV_vs_WT_F03.23663.23663.3 1.92E-08 15/64 K.VQYPDYYAIIKEPIDLK.T "sp|Q86U86|PB1_HUMAN,tr|H0Y5B5|H0Y5B5_HUMAN,tr|E7EVG2|E7EVG2_HUMAN" 3 2067.0928 0.52 38148 23663 3 2067.094537 690.0382 Protein polybromo-1 OS=Homo sapiens OX=9606 GN=PBRM1 PE=1 SV=1 4.56 3688.9 - 1.80E+06 - - - 0.8185 - 2.989 0.541 - 224.4 1 2 1 0.0017 17 0 0 0 2.57E+07 4.97E+07 - - - 7.3373 0.9999 221125_WJC_METTL3_EV_vs_WT_F03.23665.23665.2 3.37E-05 18-Dec K.C[160.03]NEIINWLDK[136.11].N "sp|P11142|HSP7C_HUMAN,tr|E9PNE6|E9PNE6_HUMAN,tr|A8K7Q2|A8K7Q2_HUMAN,tr|E9PKE3|E9PKE3_HUMAN,tr|E9PM13|E9PM13_HUMAN,tr|E9PS65|E9PS65_HUMAN" 6 1311.6373 0.1 38150 23665 2 1311.637544 656.8259 Heat shock cognate 71 kDa protein OS=Homo sapiens OX=9606 GN=HSPA8 PE=1 SV=1 4.37 3689 - 1.79E+06 - - - 0.2074 - 2.41 0.53 - 498.7 1 2 0 0.0003 10 0 0 0 1.94E+06 1.87E+07 - - - 5.4108 0.9998 221125_WJC_METTL3_EV_vs_WT_F03.23666.23666.3 0.000229 18/80 R.GLTLAPGLSPARPLFGSDFEK.E sp|Q8IU81|I2BP1_HUMAN 1 2172.1579 1.73 38151 23666 3 2172.160471 725.0599 Interferon regulatory factor 2-binding protein 1 OS=Homo sapiens OX=9606 GN=IRF2BP1 PE=1 SV=1 6.07 3689.1 - 1.55E+06 - - - 1.1813 - 2.917 0.326 - 207.1 1 2 0 0.0026 21 0 0 0 3.29E+07 1.90E+07 - - - 4.7405 1 221125_WJC_METTL3_EV_vs_WT_F03.23667.23667.2 6.21E-14 21/42 R.GEVPC[160.03]TVTSASPLEEATLSELK[136.11].T "sp|P48047|ATPO_HUMAN,tr|H7C068|H7C068_HUMAN" 2 2325.1501 0.9 38152 23667 2 2325.146532 1163.5823 "ATP synthase subunit O, mitochondrial OS=Homo sapiens OX=9606 GN=ATP5PO PE=1 SV=1" 4.09 3689.2 - 1.30E+06 - - - -1.5384 - 3.941 0.733 - 1070.8 1 2 0 -0.0036 22 0 0 0 1.92E+07 2.14E+07 - - - 7.8255 1 221125_WJC_METTL3_EV_vs_WT_F03.23670.23670.2 7.62E-10 15/28 R.SSC[160.03]DLQILDAAIVEK.L "sp|Q8IZH2|XRN1_HUMAN,tr|H7C5E4|H7C5E4_HUMAN" 2 1660.8342 1.41 38155 23670 2 1660.834196 831.4244 5'-3' exoribonuclease 1 OS=Homo sapiens OX=9606 GN=XRN1 PE=1 SV=1 4.03 3689.6 - 652835 - - - 0.0048 - 3.357 0.637 - 981.6 1 2 0 0 15 0 0 0 1.16E+07 8.20E+06 - - - 6.7233 0.9975 221125_WJC_METTL3_EV_vs_WT_F03.23676.23676.3 1.76E-06 14/92 Y.SFGSGGGYGSSFGGVDGLLAGGEK.A "sp|Q04695|K1C17_HUMAN,tr|K7EPJ9|K7EPJ9_HUMAN" 2 2161.9916 1.14 38159 23676 3 2161.992139 721.6712 "Keratin, type I cytoskeletal 17 OS=Homo sapiens OX=9606 GN=KRT17 PE=1 SV=2" 4.37 3690.3 - 3.39E+06 - - - 0.2368 - 2.336 0.565 - 155 1 1 0 0.0005 24 0 0 0 3.30E+07 2.90E+07 - - - 6.8096 1 221125_WJC_METTL3_EV_vs_WT_F03.23679.23679.2 1.58E-17 20/46 Y.SFGSGGGYGSSFGGVDGLLAGGEK.A "sp|Q04695|K1C17_HUMAN,tr|K7EPJ9|K7EPJ9_HUMAN" 2 2161.9916 17.86 38162 23679 2 2161.993018 1082.0031 "Keratin, type I cytoskeletal 17 OS=Homo sapiens OX=9606 GN=KRT17 PE=1 SV=2" 4.37 3690.6 - 2.50E+06 - - - 0.6434 - 3.884 0.768 - 963.8 1 1 0 0.0014 24 0 0 0 2.50E+07 1.40E+06 - - - 8.0489 0.9653 221125_WJC_METTL3_EV_vs_WT_F03.23680.23680.3 0.00166 Dec-56 L.QAQISALEEQLQQIR.A "sp|P13645|K1C10_HUMAN,tr|A0A1B0GVI3|A0A1B0GVI3_HUMAN" 2 1753.9323 44.61 38163 23680 3 1753.933874 585.6514 "Keratin, type I cytoskeletal 10 OS=Homo sapiens OX=9606 GN=KRT10 PE=1 SV=6" 4.53 3690.6 - 2.45E+06 - - - 0.9191 - 2.564 0.285 - 178.4 1 1 0 0.0016 15 0 0 0 2.70E+07 6.06E+05 - - - 4.1739 1 221125_WJC_METTL3_EV_vs_WT_F03.23684.23684.3 1.69E-13 30/104 R.AAASAALELPLGPAPVSVAPQAEAEAR.S sp|P57086|SCND1_HUMAN 1 2556.3548 4.41 38167 23684 3 2556.35594 853.1255 SCAN domain-containing protein 1 OS=Homo sapiens OX=9606 GN=SCAND1 PE=1 SV=1 4.25 3691.1 - 1.06E+06 - - - 0.4589 - 5.629 0.68 - 691.8 1 2 0 0.0012 27 0 0 0 4.31E+07 9.76E+06 - - - 10.0963 0.9999 221125_WJC_METTL3_EV_vs_WT_F03.23685.23685.2 0.000334 26-Dec R.GLGWVQFSSEEGLR[166.11].N "sp|Q9GZT3|SLIRP_HUMAN,tr|H0YJW7|H0YJW7_HUMAN,tr|A0A087WUN7|A0A087WUN7_HUMAN,tr|G3V2S9|G3V2S9_HUMAN,tr|H0YJ40|H0YJ40_HUMAN,tr|G3V4X6|G3V4X6_HUMAN" 6 1573.7764 1.24 38168 23685 2 1573.775878 787.8955 "SRA stem-loop-interacting RNA-binding protein, mitochondrial OS=Homo sapiens OX=9606 GN=SLIRP PE=1 SV=1" 4.53 3691.2 - 1.05E+06 - - - -0.3488 - 2.799 0.48 - 456.1 1 2 0 -0.0005 14 0 0 0 1.35E+07 1.08E+07 - - - 5.169 1 221125_WJC_METTL3_EV_vs_WT_F03.23686.23686.3 3.25E-13 23/100 R.TPYTMSYGDSLYYNNAYGALDAYYK[136.11]R[166.11].C sp|Q9BWF3|RBM4_HUMAN 1 3077.3872 1.41 38169 23686 3 3077.382068 1026.803 RNA-binding protein 4 OS=Homo sapiens OX=9606 GN=RBM4 PE=1 SV=1 5.62 3691.3 - 974046 - - - -1.6706 - 3.953 0.733 - 410.3 1 2 0 -0.0051 26 0 0 0 8.26E+06 5.84E+06 - - - 9.873 1 221125_WJC_METTL3_EV_vs_WT_F03.23687.23687.2 1.25E-11 16/34 R.AAVPSGASTGIYEALELR[166.11].D "sp|P13929|ENOB_HUMAN,sp|P06733|ENOA_HUMAN,sp|P09104|ENOG_HUMAN,tr|E5RI09|E5RI09_HUMAN,tr|F5H0C8|F5H0C8_HUMAN,tr|A0A2R8Y6G6|A0A2R8Y6G6_HUMAN,tr|A0A2R8YEG5|A0A2R8YEG5_HUMAN,tr|K7ERS8|K7ERS8_HUMAN,tr|K7EM90|K7EM90_HUMAN,tr|E5RG95|E5RG95_HUMAN,tr|A0A2R8Y879|A0A2R8Y879_HUMAN,tr|A0A2R8Y798|A0A2R8Y798_HUMAN,tr|F5H1C3|F5H1C3_HUMAN,tr|E5RGZ4|E5RGZ4_HUMAN,tr|A0A2R8YEM5|A0A2R8YEM5_HUMAN,tr|K7EPM1|K7EPM1_HUMAN,tr|K7EKN2|K7EKN2_HUMAN" 17 1813.9449 1.1 38170 23687 2 1813.946472 907.9798 Beta-enolase OS=Homo sapiens OX=9606 GN=ENO3 PE=1 SV=5 4.53 3691.4 - 917387 - - - 0.8396 - 3.351 0.642 - 972.7 1 2 0 0.0015 18 0 0 0 3.41E+07 3.10E+07 - - - 6.7554 1 221125_WJC_METTL3_EV_vs_WT_F03.23688.23688.3 1.90E-07 16/52 K.NNGAGYFLEHLAFK[136.11].G sp|P31930|QCR1_HUMAN 1 1587.7925 1.2 38171 23688 3 1587.792532 530.2715 "Cytochrome b-c1 complex subunit 1, mitochondrial OS=Homo sapiens OX=9606 GN=UQCRC1 PE=1 SV=3" 6.75 3691.5 - 855081 - - - 0.0031 - 3.078 0.561 - 320.4 1 2 0 0 14 0 0 0 3.53E+07 2.94E+07 - - - 7.7824 1 221125_WJC_METTL3_EV_vs_WT_F03.23689.23689.3 2.62E-09 19/96 K.GIPLATGDTSPEPELLPGAPLPPPK[136.11].E "sp|O75821|EIF3G_HUMAN,tr|K7ER90|K7ER90_HUMAN,tr|K7EL20|K7EL20_HUMAN,tr|K7ENA8|K7ENA8_HUMAN,tr|K7EL60|K7EL60_HUMAN" 5 2471.3403 1.84 38172 23689 3 2471.344056 824.7874 Eukaryotic translation initiation factor 3 subunit G OS=Homo sapiens OX=9606 GN=EIF3G PE=1 SV=2 4.14 3691.7 - 827341 - - - 1.5231 - 2.964 0.611 - 229 1 2 0 0.0038 25 0 0 0 3.43E+07 1.86E+07 - - - 7.8507 1 221125_WJC_METTL3_EV_vs_WT_F03.23690.23690.2 1.18E-06 14/28 R.SSC[160.03]DLQILDAAIVEK[136.11].L "sp|Q8IZH2|XRN1_HUMAN,tr|H7C5E4|H7C5E4_HUMAN" 2 1668.8484 1.56 38173 23690 2 1668.845238 835.4315 5'-3' exoribonuclease 1 OS=Homo sapiens OX=9606 GN=XRN1 PE=1 SV=1 4.03 3691.8 - 693182 - - - -1.8875 - 2.937 0.555 - 745.2 1 2 0 -0.0032 15 0 0 0 1.16E+07 7.41E+06 - - - 5.7881 1 221125_WJC_METTL3_EV_vs_WT_F03.23696.23696.3 3.31E-10 28/84 K.QVLGQMVIDEELLGDGHSYSPR.A sp|P28070|PSB4_HUMAN 1 2442.1849 1.72 38177 23696 3 2442.187648 815.0689 Proteasome subunit beta type-4 OS=Homo sapiens OX=9606 GN=PSMB4 PE=1 SV=4 4.31 3692.5 - 6.57E+06 - - - 1.1154 - 4.907 0.657 - 896.8 1 2 0 0.0027 22 0 0 0 7.22E+07 4.19E+07 - - - 9.6353 1 221125_WJC_METTL3_EV_vs_WT_F03.23697.23697.3 3.13E-05 18/60 K.SDALETLGFLNHYQMK[136.11].N "sp|P14866|HNRPL_HUMAN,tr|M0QYT0|M0QYT0_HUMAN,tr|A0A3B3ITJ4|A0A3B3ITJ4_HUMAN,tr|M0QXS5|M0QXS5_HUMAN,tr|M0R076|M0R076_HUMAN" 5 1873.9124 1.23 38178 23697 3 1873.913749 625.6447 Heterogeneous nuclear ribonucleoprotein L OS=Homo sapiens OX=9606 GN=HNRNPL PE=1 SV=2 5.3 3692.5 - 6.69E+06 - - - 0.7279 - 3.543 0.57 - 456.7 1 2 0 0.0014 16 0 0 0 1.74E+08 1.41E+08 - - - 8.1403 1 221125_WJC_METTL3_EV_vs_WT_F03.23698.23698.3 3.10E-07 20/60 K.SDALETLGFLNHYQMK.N "sp|P14866|HNRPL_HUMAN,tr|M0QYT0|M0QYT0_HUMAN,tr|A0A3B3ITJ4|A0A3B3ITJ4_HUMAN,tr|M0QXS5|M0QXS5_HUMAN,tr|M0R076|M0R076_HUMAN" 5 1865.8982 1.19 38179 23698 3 1865.899253 622.9733 Heterogeneous nuclear ribonucleoprotein L OS=Homo sapiens OX=9606 GN=HNRNPL PE=1 SV=2 5.3 3692.6 - 5.96E+06 - - - 0.5724 - 3.781 0.587 - 507.2 1 2 0 0.0011 16 0 0 0 1.74E+08 1.46E+08 - - - 8.4967 1 221125_WJC_METTL3_EV_vs_WT_F03.23699.23699.2 3.52E-14 24/42 R.GEVPC[160.03]TVTSASPLEEATLSELK.T "sp|P48047|ATPO_HUMAN,tr|H7C068|H7C068_HUMAN" 2 2317.1359 0.9 38180 23699 2 2317.139867 1159.5752 "ATP synthase subunit O, mitochondrial OS=Homo sapiens OX=9606 GN=ATP5PO PE=1 SV=1" 4.09 3692.7 - 1.80E+06 - - - 1.7081 - 4.274 0.719 - 1682.8 1 2 0 0.004 22 0 0 0 1.92E+07 2.14E+07 - - - 7.9215 1 221125_WJC_METTL3_EV_vs_WT_F03.23700.23700.2 1.60E-11 22/50 K.EGPYDVVVLPGGNLGAQNLSESAAVK.E "sp|Q99497|PARK7_HUMAN,tr|K7EN27|K7EN27_HUMAN" 2 2583.318 4.15 38181 23700 2 2583.322543 1292.6663 Parkinson disease protein 7 OS=Homo sapiens OX=9606 GN=PARK7 PE=1 SV=2 4.14 3692.9 - 1.31E+06 - - - 1.7404 - 3.464 0.69 - 524.8 1 2 0 0.0045 26 0 0 0 2.25E+07 5.43E+06 - - - 7.1905 1 221125_WJC_METTL3_EV_vs_WT_F03.23702.23702.2 1.23E-11 19/34 R.SSLSSAQADFNQLAELDR.Q "sp|Q13813|SPTN1_HUMAN,tr|A0A0D9SF54|A0A0D9SF54_HUMAN,tr|A0A0D9SGF6|A0A0D9SGF6_HUMAN" 3 1950.9283 2.91 38183 23702 2 1950.932353 976.4714 "Spectrin alpha chain, non-erythrocytic 1 OS=Homo sapiens OX=9606 GN=SPTAN1 PE=1 SV=3" 4.03 3693.1 - 895366 - - - 2.078 - 4.001 0.596 - 1206.7 1 2 0 0.0041 18 0 0 0 8.42E+06 2.89E+06 - - - 6.8507 1 221125_WJC_METTL3_EV_vs_WT_F03.23703.23703.2 3.10E-13 14/32 K.HFIAEYDTSTQDFGEPF.- tr|F8W0Q9|F8W0Q9_HUMAN 1 2002.8585 - 38184 23703 2 2002.850388 1002.4365 Periphilin-1 OS=Homo sapiens OX=9606 GN=PPHLN1 PE=1 SV=1 3.91 3693.2 - 864545 - - - -4.0442 - 3.198 0.728 - 285.1 1 2 0 -0.0081 17 0 0 0 - - - - - 7.2736 1 221125_WJC_METTL3_EV_vs_WT_F03.23711.23711.3 7.56E-07 23/84 R.GEVPC[160.03]TVTSASPLEEATLSELK[136.11].T "sp|P48047|ATPO_HUMAN,tr|H7C068|H7C068_HUMAN" 2 2325.1501 1.28 38190 23711 3 2325.149681 776.0573 "ATP synthase subunit O, mitochondrial OS=Homo sapiens OX=9606 GN=ATP5PO PE=1 SV=1" 4.09 3694.3 - 5.16E+06 - - - -0.1841 - 3.971 0.647 - 703 1 2 0 -0.0004 22 0 0 0 9.41E+07 7.36E+07 - - - 9.0227 1 221125_WJC_METTL3_EV_vs_WT_F03.23712.23712.3 9.93E-09 27/84 K.QVLGQMVIDEELLGDGHSYSPR[166.11].A sp|P28070|PSB4_HUMAN 1 2452.1932 1.72 38191 23712 3 2452.192628 818.405 Proteasome subunit beta type-4 OS=Homo sapiens OX=9606 GN=PSMB4 PE=1 SV=4 4.31 3694.3 - 4.51E+06 - - - -0.2308 - 4.379 0.652 - 765.4 1 2 0 -0.0006 22 0 0 0 7.22E+07 4.19E+07 - - - 9.3103 1 221125_WJC_METTL3_EV_vs_WT_F03.23715.23715.2 1.20E-08 19/34 R.AAVPSGASTGIYEALELR.D "sp|P13929|ENOB_HUMAN,sp|P06733|ENOA_HUMAN,sp|P09104|ENOG_HUMAN,tr|E5RI09|E5RI09_HUMAN,tr|F5H0C8|F5H0C8_HUMAN,tr|A0A2R8Y6G6|A0A2R8Y6G6_HUMAN,tr|A0A2R8YEG5|A0A2R8YEG5_HUMAN,tr|K7ERS8|K7ERS8_HUMAN,tr|K7EM90|K7EM90_HUMAN,tr|E5RG95|E5RG95_HUMAN,tr|A0A2R8Y879|A0A2R8Y879_HUMAN,tr|A0A2R8Y798|A0A2R8Y798_HUMAN,tr|F5H1C3|F5H1C3_HUMAN,tr|E5RGZ4|E5RGZ4_HUMAN,tr|A0A2R8YEM5|A0A2R8YEM5_HUMAN,tr|K7EPM1|K7EPM1_HUMAN,tr|K7EKN2|K7EKN2_HUMAN" 17 1803.9367 1.1 38194 23715 2 1803.937297 902.9756 Beta-enolase OS=Homo sapiens OX=9606 GN=ENO3 PE=1 SV=5 4.53 3694.6 - 2.46E+06 - - - 0.3426 - 3.398 0.55 - 1375 1 2 0 0.0006 18 0 0 0 3.41E+07 3.10E+07 - - - 6.1104 0.9999 221125_WJC_METTL3_EV_vs_WT_F03.23717.23717.3 4.72E-05 14/68 K.VSQFLVDGVC[160.03]TVANC[160.03]VGK[136.11].E sp|Q8N0X7|SPART_HUMAN 1 1959.9638 1.14 38196 23717 3 1959.958164 654.3285 Spartin OS=Homo sapiens OX=9606 GN=SPART PE=1 SV=1 5.79 3694.7 - 2.06E+06 - - - -2.8597 - 2.757 0.454 - 267.5 1 2 0 -0.0056 18 0 0 0 3.34E+07 2.93E+07 - - - 6.1254 1 221125_WJC_METTL3_EV_vs_WT_F03.23720.23720.3 8.52E-08 20/96 K.GIPLATGDTSPEPELLPGAPLPPPK.E "sp|O75821|EIF3G_HUMAN,tr|K7ER90|K7ER90_HUMAN,tr|K7EL20|K7EL20_HUMAN,tr|K7ENA8|K7ENA8_HUMAN,tr|K7EL60|K7EL60_HUMAN" 5 2463.3261 -1 38199 23720 3 2463.327748 822.116 Eukaryotic translation initiation factor 3 subunit G OS=Homo sapiens OX=9606 GN=EIF3G PE=1 SV=2 4.14 3695.1 - 1.05E+06 - - - 0.6723 - 2.747 0.576 - 268.6 1 2 0 0.0017 25 0 0 0 0.00E+00 0.00E+00 - - - 7.2862 1 221125_WJC_METTL3_EV_vs_WT_F03.23722.23722.2 5.43E-12 19/30 K.SDALETLGFLNHYQMK.N "sp|P14866|HNRPL_HUMAN,tr|M0QYT0|M0QYT0_HUMAN,tr|A0A3B3ITJ4|A0A3B3ITJ4_HUMAN,tr|M0QXS5|M0QXS5_HUMAN,tr|M0R076|M0R076_HUMAN" 5 1865.8982 1.54 38201 23722 2 1865.90414 933.9564 Heterogeneous nuclear ribonucleoprotein L OS=Homo sapiens OX=9606 GN=HNRNPL PE=1 SV=2 5.3 3695.3 - 826205 - - - 3.1915 - 3.804 0.695 - 1033.1 1 2 0 0.006 16 0 0 0 1.63E+07 1.06E+07 - - - 7.4571 0.9995 221125_WJC_METTL3_EV_vs_WT_F03.23723.23723.2 0.000429 14/30 R.ALGEPITLFGEGPAER.R sp|O43172|PRP4_HUMAN 1 1655.8519 3.75 38202 23723 2 1655.847183 828.9332 U4\U6 small nuclear ribonucleoprotein Prp4 OS=Homo sapiens OX=9606 GN=PRPF4 PE=1 SV=2 4.25 3695.4 - 610434 - - - -2.8402 - 2.833 0.43 - 619 1 2 0 -0.0047 16 0 0 0 2.04E+07 5.43E+06 - - - 4.7757 1 221125_WJC_METTL3_EV_vs_WT_F03.23727.23727.2 9.57E-11 13/42 K.EEKDPGMGAMGGMGGGMGGGMF.- "sp|P10809|CH60_HUMAN,tr|A0A7I2V2X6|A0A7I2V2X6_HUMAN,tr|A0A7I2YQK6|A0A7I2YQK6_HUMAN" 3 2059.793 1.79 38206 23727 2 2059.797032 1030.9038 "60 kDa heat shock protein, mitochondrial OS=Homo sapiens OX=9606 GN=HSPD1 PE=1 SV=2" 4.14 3696 - 358658 - - - 1.9531 - 2.955 0.646 - 249.1 1 2 1 0.004 22 0 0 0 4.45E+06 2.49E+06 - - - 6.4749 0.9995 221125_WJC_METTL3_EV_vs_WT_F03.23728.23728.3 0.000113 Dec-44 K.NMPLQHLLEQIK.E sp|P15924|DESP_HUMAN 1 1462.7966 25.56 38207 23728 3 1462.79949 488.6061 Desmoplakin OS=Homo sapiens OX=9606 GN=DSP PE=1 SV=3 6.75 3696.1 - 315118 - - - 1.962 - 1.852 0.368 - 185.9 1 2 0 0.0029 12 0 0 0 1.56E+07 6.12E+05 - - - 4.3502 1 221125_WJC_METTL3_EV_vs_WT_F03.23733.23733.2 9.68E-13 22/38 K.TIGGGDDSFNTFFSETGAGK[136.11].H "sp|Q6PEY2|TBA3E_HUMAN,sp|P0DPH7|TBA3C_HUMAN,sp|Q71U36|TBA1A_HUMAN,sp|P0DPH8|TBA3D_HUMAN,sp|P68363|TBA1B_HUMAN,sp|Q9BQE3|TBA1C_HUMAN,tr|F8W0F6|F8W0F6_HUMAN,tr|F8VS66|F8VS66_HUMAN,tr|F8VWV9|F8VWV9_HUMAN,tr|F8VRZ4|F8VRZ4_HUMAN,tr|F8VVB9|F8VVB9_HUMAN,tr|A0A1W2PQM2|A0A1W2PQM2_HUMAN,tr|F5H5D3|F5H5D3_HUMAN,tr|F8VRK0|F8VRK0_HUMAN,tr|F8VQQ4|F8VQQ4_HUMAN,tr|F8VX09|F8VX09_HUMAN,tr|A0A7P0Z4A1|A0A7P0Z4A1_HUMAN" 17 2014.9 0.71 38210 23733 2 2014.898898 1008.4573 Tubulin alpha-3E chain OS=Homo sapiens OX=9606 GN=TUBA3E PE=1 SV=2 4.03 3696.8 - 6.99E+06 - - - -0.5296 - 3.523 0.742 - 936.6 1 2 0 -0.0011 20 0 0 0 2.25E+08 3.15E+08 - - - 7.6172 1 221125_WJC_METTL3_EV_vs_WT_F03.23734.23734.3 8.77E-10 13/76 K.TIGGGDDSFNTFFSETGAGK[136.11].H "sp|Q6PEY2|TBA3E_HUMAN,sp|P0DPH7|TBA3C_HUMAN,sp|Q71U36|TBA1A_HUMAN,sp|P0DPH8|TBA3D_HUMAN,sp|P68363|TBA1B_HUMAN,sp|Q9BQE3|TBA1C_HUMAN,tr|F8W0F6|F8W0F6_HUMAN,tr|F8VS66|F8VS66_HUMAN,tr|F8VWV9|F8VWV9_HUMAN,tr|F8VRZ4|F8VRZ4_HUMAN,tr|F8VVB9|F8VVB9_HUMAN,tr|A0A1W2PQM2|A0A1W2PQM2_HUMAN,tr|F5H5D3|F5H5D3_HUMAN,tr|F8VRK0|F8VRK0_HUMAN,tr|F8VQQ4|F8VQQ4_HUMAN,tr|F8VX09|F8VX09_HUMAN,tr|A0A7P0Z4A1|A0A7P0Z4A1_HUMAN" 17 2014.9 0.79 38211 23734 3 2014.900217 672.6406 Tubulin alpha-3E chain OS=Homo sapiens OX=9606 GN=TUBA3E PE=1 SV=2 4.03 3696.8 - 4.07E+06 - - - 0.1251 - 2.546 0.67 - 127.8 1 2 0 0.0003 20 0 0 0 8.37E+07 1.06E+08 - - - 8.2769 1 221125_WJC_METTL3_EV_vs_WT_F03.23735.23735.2 6.00E-11 18/38 K.TIGGGDDSFNTFFSETGAGK.H "sp|Q6PEY2|TBA3E_HUMAN,sp|P0DPH7|TBA3C_HUMAN,sp|Q71U36|TBA1A_HUMAN,sp|P0DPH8|TBA3D_HUMAN,sp|P68363|TBA1B_HUMAN,sp|Q9BQE3|TBA1C_HUMAN,tr|F8W0F6|F8W0F6_HUMAN,tr|F8VS66|F8VS66_HUMAN,tr|F8VWV9|F8VWV9_HUMAN,tr|F8VRZ4|F8VRZ4_HUMAN,tr|F8VVB9|F8VVB9_HUMAN,tr|A0A1W2PQM2|A0A1W2PQM2_HUMAN,tr|F5H5D3|F5H5D3_HUMAN,tr|F8VRK0|F8VRK0_HUMAN,tr|F8VQQ4|F8VQQ4_HUMAN,tr|F8VX09|F8VX09_HUMAN,tr|A0A7P0Z4A1|A0A7P0Z4A1_HUMAN" 17 2006.8858 0.71 38212 23735 2 2006.884734 1004.4502 Tubulin alpha-3E chain OS=Homo sapiens OX=9606 GN=TUBA3E PE=1 SV=2 4.03 3696.9 - 3.83E+06 - - - -0.5137 - 3.27 0.753 - 495.1 1 2 0 -0.001 20 0 0 0 2.25E+08 3.15E+08 - - - 7.5152 1 221125_WJC_METTL3_EV_vs_WT_F03.23736.23736.3 0.000462 15/52 K.NNGAGYFLEHLAFK.G sp|P31930|QCR1_HUMAN 1 1579.7783 1.2 38213 23736 3 1579.77864 527.6001 "Cytochrome b-c1 complex subunit 1, mitochondrial OS=Homo sapiens OX=9606 GN=UQCRC1 PE=1 SV=3" 6.75 3696.9 - 3.14E+06 - - - 0.1981 - 3.095 0.567 - 293.1 1 2 0 0.0003 14 0 0 0 3.53E+07 2.94E+07 - - - 7.8639 1 221125_WJC_METTL3_EV_vs_WT_F03.23740.23740.2 1.35E-09 17/30 K.SDALETLGFLNHYQMK[136.11].N "sp|P14866|HNRPL_HUMAN,tr|M0QYT0|M0QYT0_HUMAN,tr|A0A3B3ITJ4|A0A3B3ITJ4_HUMAN,tr|M0QXS5|M0QXS5_HUMAN,tr|M0R076|M0R076_HUMAN" 5 1873.9124 1.54 38217 23740 2 1873.914007 937.9635 Heterogeneous nuclear ribonucleoprotein L OS=Homo sapiens OX=9606 GN=HNRNPL PE=1 SV=2 5.3 3697.4 - 1.09E+06 - - - 0.8656 - 3.448 0.606 - 735.8 1 2 0 0.0016 16 0 0 0 1.63E+07 1.06E+07 - - - 6.5596 0.9978 221125_WJC_METTL3_EV_vs_WT_F03.23741.23741.3 0.0477 Sep-44 K.EDLHDMLASLGK[136.11].N "sp|O14950|ML12B_HUMAN,sp|P19105|ML12A_HUMAN,sp|P24844|MYL9_HUMAN,tr|J3KTJ1|J3KTJ1_HUMAN,tr|J3QRS3|J3QRS3_HUMAN" 5 1335.6584 1.22 38218 23741 3 1335.658333 446.2267 Myosin regulatory light chain 12B OS=Homo sapiens OX=9606 GN=MYL12B PE=1 SV=2 4.54 3697.5 - 667525 - - - -0.0517 - 1.402 0.294 - 118.8 1 2 0 -0.0001 12 0 0 0 6.46E+06 5.29E+06 - - - 2.7544 0.9977 221125_WJC_METTL3_EV_vs_WT_F03.23743.23743.3 0.434 Oct-44 K.EDLHDMLASLGK.N "sp|O14950|ML12B_HUMAN,sp|P19105|ML12A_HUMAN,sp|P24844|MYL9_HUMAN,tr|J3KTJ1|J3KTJ1_HUMAN,tr|J3QRS3|J3QRS3_HUMAN" 5 1327.6442 1.22 38220 23743 3 1327.643175 443.5553 Myosin regulatory light chain 12B OS=Homo sapiens OX=9606 GN=MYL12B PE=1 SV=2 4.54 3697.7 - 640797 - - - -0.7736 - 1.588 0.261 - 127.9 1 2 0 -0.001 12 0 0 0 6.46E+06 5.29E+06 - - - 2.7315 1 221125_WJC_METTL3_EV_vs_WT_F03.23747.23747.3 3.08E-07 13/68 R.AAVPSGASTGIYEALELR.D "sp|P13929|ENOB_HUMAN,sp|P06733|ENOA_HUMAN,sp|P09104|ENOG_HUMAN,tr|E5RI09|E5RI09_HUMAN,tr|F5H0C8|F5H0C8_HUMAN,tr|A0A2R8Y6G6|A0A2R8Y6G6_HUMAN,tr|A0A2R8YEG5|A0A2R8YEG5_HUMAN,tr|K7ERS8|K7ERS8_HUMAN,tr|K7EM90|K7EM90_HUMAN,tr|E5RG95|E5RG95_HUMAN,tr|A0A2R8Y879|A0A2R8Y879_HUMAN,tr|A0A2R8Y798|A0A2R8Y798_HUMAN,tr|F5H1C3|F5H1C3_HUMAN,tr|E5RGZ4|E5RGZ4_HUMAN,tr|A0A2R8YEM5|A0A2R8YEM5_HUMAN,tr|K7EPM1|K7EPM1_HUMAN,tr|K7EKN2|K7EKN2_HUMAN" 17 1803.9367 1.44 38222 23747 3 1803.936312 602.3195 Beta-enolase OS=Homo sapiens OX=9606 GN=ENO3 PE=1 SV=5 4.53 3698.2 - 1.62E+06 - - - -0.2034 - 2.692 0.503 - 209 1 2 0 -0.0004 18 0 0 0 3.39E+07 2.35E+07 - - - 6.6138 0.9777 221125_WJC_METTL3_EV_vs_WT_F03.23748.23748.3 0.0013 14/72 K.IELFGR[166.11]PHNVQPNWITLGN.Q sp|Q86U44|MTA70_HUMAN 1 2214.1573 0.05 38223 23748 3 2214.155521 739.0597 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 6.75 3698.2 - 1.05E+07 - - - -0.822 - 2.383 0.343 - 158.9 1 1 0 -0.0018 19 0 0 0 7.46E+06 1.50E+08 - - - 4.497 1 221125_WJC_METTL3_EV_vs_WT_F03.23754.23754.4 5.01E-07 21/102 R.VC[160.03]APEETTFHLLHLSLMR.E "sp|Q8IZH2|XRN1_HUMAN,tr|C9JCZ8|C9JCZ8_HUMAN" 2 2153.0762 1.71 38229 23754 4 2153.078945 539.2763 5'-3' exoribonuclease 1 OS=Homo sapiens OX=9606 GN=XRN1 PE=1 SV=1 6 3698.8 - 728778 - - - 1.2907 - 3.611 0.561 - 419.5 1 2 0 0.0028 18 0 0 0 1.25E+07 7.32E+06 - - - 4.548 0.9937 221125_WJC_METTL3_EV_vs_WT_F03.23757.23757.2 0.183 26-Nov K.ETLTFPPEVPISEK.A sp|Q15208|STK38_HUMAN 1 1585.8239 15.15 38231 23757 2 1585.827715 793.9192 Serine\threonine-protein kinase 38 OS=Homo sapiens OX=9606 GN=STK38 PE=1 SV=1 4.25 3699.2 - 872984 - - - 2.3805 - 1.541 0.22 - 167 1 2 0 0.0038 14 0 0 0 1.25E+07 8.22E+05 - - - 1.7499 1 221125_WJC_METTL3_EV_vs_WT_F03.23759.23759.3 0.00213 Dec-76 K.TIGGGDDSFNTFFSETGAGK.H "sp|Q6PEY2|TBA3E_HUMAN,sp|P0DPH7|TBA3C_HUMAN,sp|Q71U36|TBA1A_HUMAN,sp|P0DPH8|TBA3D_HUMAN,sp|P68363|TBA1B_HUMAN,sp|Q9BQE3|TBA1C_HUMAN,tr|F8W0F6|F8W0F6_HUMAN,tr|F8VS66|F8VS66_HUMAN,tr|F8VWV9|F8VWV9_HUMAN,tr|F8VRZ4|F8VRZ4_HUMAN,tr|F8VVB9|F8VVB9_HUMAN,tr|A0A1W2PQM2|A0A1W2PQM2_HUMAN,tr|F5H5D3|F5H5D3_HUMAN,tr|F8VRK0|F8VRK0_HUMAN,tr|F8VQQ4|F8VQQ4_HUMAN,tr|F8VX09|F8VX09_HUMAN,tr|A0A7P0Z4A1|A0A7P0Z4A1_HUMAN" 17 2006.8858 0.79 38232 23759 3 2006.887304 669.9692 Tubulin alpha-3E chain OS=Homo sapiens OX=9606 GN=TUBA3E PE=1 SV=2 4.03 3699.4 - 6.64E+06 - - - 0.7669 - 2.203 0.523 - 109.2 1 2 0 0.0015 20 0 0 0 8.37E+07 1.06E+08 - - - 6.2866 1 221125_WJC_METTL3_EV_vs_WT_F03.23761.23761.2 0.0146 16/24 R.TTNFAGILSQGLR[166.11].L "sp|P09874|PARP1_HUMAN,tr|A0A7I2V3E1|A0A7I2V3E1_HUMAN" 2 1386.7495 0.94 38234 23761 2 1386.750169 694.382 Poly [ADP-ribose] polymerase 1 OS=Homo sapiens OX=9606 GN=PARP1 PE=1 SV=4 9.41 3699.5 - 5.16E+06 - - - 0.4947 - 3.196 0.556 - 990.2 1 2 0 0.0007 13 0 0 0 7.07E+07 7.52E+07 - - - 6.1295 1 221125_WJC_METTL3_EV_vs_WT_F03.23765.23765.3 1.89E-15 26/84 R.LVQDYGLESEVAQHLAATYGDK.A sp|P43304|GPDM_HUMAN 1 2406.1703 0.69 38238 23765 3 2406.167002 803.064 "Glycerol-3-phosphate dehydrogenase, mitochondrial OS=Homo sapiens OX=9606 GN=GPD2 PE=1 SV=3" 4.31 3699.9 - 1.55E+06 - - - -1.379 - 4.603 0.673 - 766.4 1 2 0 -0.0033 22 0 0 0 1.50E+07 2.17E+07 - - - 9.6619 0.9999 221125_WJC_METTL3_EV_vs_WT_F03.23767.23767.3 9.36E-08 14/68 K.FIIHAPPGEFNEVFNDVR.L "sp|P47755|CAZA2_HUMAN,tr|C9JUG7|C9JUG7_HUMAN,tr|A0A0D9SET8|A0A0D9SET8_HUMAN,tr|F8W9N7|F8W9N7_HUMAN" 4 2100.0429 1 38240 23767 3 2100.036774 701.0216 F-actin-capping protein subunit alpha-2 OS=Homo sapiens OX=9606 GN=CAPZA2 PE=1 SV=3 4.65 3700 - 1.35E+06 - - - -2.9052 - 2.755 0.504 - 168.2 1 2 0 -0.0061 18 0 0 0 1.18E+07 1.19E+07 - - - 6.6809 1 221125_WJC_METTL3_EV_vs_WT_F03.23780.23780.2 3.43E-07 18/30 K.ASSTSPVEISEWLDQK.L "sp|P13804|ETFA_HUMAN,tr|H0YK49|H0YK49_HUMAN,tr|H0YL12|H0YL12_HUMAN,tr|H0YKF0|H0YKF0_HUMAN,tr|H0YLU7|H0YLU7_HUMAN,tr|H0YNX6|H0YNX6_HUMAN" 6 1775.8578 2.47 38251 23780 2 1775.860808 888.9362 "Electron transfer flavoprotein subunit alpha, mitochondrial OS=Homo sapiens OX=9606 GN=ETFA PE=1 SV=1" 4.14 3701.5 - 1.74E+06 - - - 1.7164 - 3.236 0.573 - 1169.8 1 2 0 0.003 16 0 0 0 2.48E+07 1.01E+07 - - - 6.1594 1 221125_WJC_METTL3_EV_vs_WT_F03.23781.23781.3 5.45E-08 20/60 K.QQEVEAITLELEELK[136.11]R[166.11].E sp|O95347|SMC2_HUMAN 1 1945.0487 0.66 38252 23781 3 1945.044757 649.3568 Structural maintenance of chromosomes protein 2 OS=Homo sapiens OX=9606 GN=SMC2 PE=1 SV=2 4.33 3701.6 - 1.71E+06 - - - -2.0231 - 3.599 0.593 - 684.3 1 2 0 -0.0039 16 0 0 0 1.37E+07 2.08E+07 - - - 8.4363 1 221125_WJC_METTL3_EV_vs_WT_F03.23787.23787.3 2.40E-12 20/76 R.ELLTTMGDR[166.11]FTDEEVDELYR[166.11].E "sp|O14950|ML12B_HUMAN,sp|P19105|ML12A_HUMAN,tr|J3QRS3|J3QRS3_HUMAN" 3 2451.1379 1.09 38256 23787 3 2451.130078 818.0532 Myosin regulatory light chain 12B OS=Homo sapiens OX=9606 GN=MYL12B PE=1 SV=2 3.95 3702.3 - 3.01E+06 - - - -3.1753 - 3.912 0.68 - 514.8 1 2 1 -0.0078 20 0 0 0 1.93E+07 1.77E+07 - - - 9.4284 0.9999 221125_WJC_METTL3_EV_vs_WT_F03.23788.23788.3 7.77E-08 17/76 R.ELLTTMGDRFTDEEVDELYR.E "sp|O14950|ML12B_HUMAN,sp|P19105|ML12A_HUMAN,tr|J3QRS3|J3QRS3_HUMAN" 3 2431.1213 1.09 38257 23788 3 2431.117921 811.3811 Myosin regulatory light chain 12B OS=Homo sapiens OX=9606 GN=MYL12B PE=1 SV=2 3.95 3702.3 - 3.85E+06 - - - -1.3985 - 3.293 0.618 - 311.2 1 2 1 -0.0034 20 0 0 0 1.93E+07 1.77E+07 - - - 8.3205 1 221125_WJC_METTL3_EV_vs_WT_F03.23790.23790.3 4.46E-09 25/72 K.DELHIVEAEAMNYEGSPIK.V "sp|P06748|NPM_HUMAN,tr|A0A7I2V4G8|A0A7I2V4G8_HUMAN,tr|A0A7I2YQC0|A0A7I2YQC0_HUMAN,tr|A0A7I2V433|A0A7I2V433_HUMAN,tr|A0A7I2V579|A0A7I2V579_HUMAN,tr|A0A7I2V2X9|A0A7I2V2X9_HUMAN,tr|A0A7I2V3G5|A0A7I2V3G5_HUMAN,tr|A0A7I2V5S2|A0A7I2V5S2_HUMAN,tr|A0A7I2V3U2|A0A7I2V3U2_HUMAN" 9 2144.0096 0.89 38259 23790 3 2144.007359 715.6771 Nucleophosmin OS=Homo sapiens OX=9606 GN=NPM1 PE=1 SV=2 4.25 3702.4 - 3.97E+06 - - - -1.0387 - 3.984 0.633 - 1006.3 1 2 0 -0.0022 19 0 0 0 1.32E+08 1.47E+08 - - - 8.9927 1 221125_WJC_METTL3_EV_vs_WT_F03.23792.23792.2 3.18E-06 15/30 K.ASSTSPVEISEWLDQK[136.11].L "sp|P13804|ETFA_HUMAN,tr|H0YK49|H0YK49_HUMAN,tr|H0YL12|H0YL12_HUMAN,tr|H0YKF0|H0YKF0_HUMAN,tr|H0YLU7|H0YLU7_HUMAN,tr|H0YNX6|H0YNX6_HUMAN" 6 1783.872 2.47 38261 23792 2 1783.867958 892.9433 "Electron transfer flavoprotein subunit alpha, mitochondrial OS=Homo sapiens OX=9606 GN=ETFA PE=1 SV=1" 4.14 3702.6 - 1.52E+06 - - - -2.2434 - 3.123 0.597 - 756.5 1 2 0 -0.004 16 0 0 0 2.48E+07 1.01E+07 - - - 6.249 0.9999 221125_WJC_METTL3_EV_vs_WT_F03.23795.23795.3 7.03E-05 Dec-76 K.FEAHPNDLYVEGLPENIPFR.S "sp|P78347|GTF2I_HUMAN,tr|A0A494C0Q7|A0A494C0Q7_HUMAN,tr|A0A494C1K3|A0A494C1K3_HUMAN" 3 2356.1488 14.84 38264 23795 3 2356.149359 786.3902 General transcription factor II-I OS=Homo sapiens OX=9606 GN=GTF2I PE=1 SV=2 4.4 3703 - 977201 - - - 0.2385 - 2.327 0.394 - 80.1 1 2 0 0.0006 20 0 0 0 1.30E+07 8.74E+05 - - - 4.9815 1 221125_WJC_METTL3_EV_vs_WT_F03.23796.23796.2 1.61E-06 15/32 R.IQEIIEQLDVTTSEYEK.E "sp|P10809|CH60_HUMAN,tr|A0A7I2V2X6|A0A7I2V2X6_HUMAN,tr|A0A7I2YQK6|A0A7I2YQK6_HUMAN,tr|A0A7I2V599|A0A7I2V599_HUMAN" 4 2037.0154 3.46 38265 23796 2 2037.018113 1019.515 "60 kDa heat shock protein, mitochondrial OS=Homo sapiens OX=9606 GN=HSPD1 PE=1 SV=2" 3.91 3703.1 - 961716 - - - 1.3407 - 3.55 0.561 - 519.7 1 2 0 0.0027 17 0 0 0 1.30E+07 3.76E+06 - - - 6.2985 0.9542 221125_WJC_METTL3_EV_vs_WT_F03.23797.23797.4 0.153 Aug-78 R.LYQHAVEYFLHAIK[136.11].Y "sp|Q9UN37|VPS4A_HUMAN,tr|I3L4J1|I3L4J1_HUMAN" 2 1738.9286 0.54 38266 23797 4 1738.924513 435.7394 Vacuolar protein sorting-associated protein 4A OS=Homo sapiens OX=9606 GN=VPS4A PE=1 SV=1 6.92 3703.2 - 720338 - - - -2.3658 - 1.354 0.175 - 37.7 1 2 0 -0.0041 14 0 0 0 2.12E+06 3.93E+06 - - - 0.8584 1 221125_WJC_METTL3_EV_vs_WT_F03.23800.23800.3 1.46E-16 30/92 R.FLEQQNQVLQTKWELLQQVDTSTR.T sp|P04264|K2C1_HUMAN 1 2931.509 999 38267 23800 3 2931.507174 978.177 "Keratin, type II cytoskeletal 1 OS=Homo sapiens OX=9606 GN=KRT1 PE=1 SV=6" 4.68 3703.6 - 6.62E+06 - - - -0.6352 - 4.875 0.715 - 1119.3 1 2 1 -0.0019 24 0 0 0 4.24E+07 0.00E+00 - - - 10.1903 1 221125_WJC_METTL3_EV_vs_WT_F03.23801.23801.3 1.48E-09 28/92 K.QLGDNEAITQEIVGC[160.03]AHLENYALK.M "sp|Q9NP79|VTA1_HUMAN,tr|Q5TGM0|Q5TGM0_HUMAN,tr|A0A087WY55|A0A087WY55_HUMAN" 3 2685.3068 1.84 38268 23801 3 2685.307176 896.1096 Vacuolar protein sorting-associated protein VTA1 homolog OS=Homo sapiens OX=9606 GN=VTA1 PE=1 SV=1 4.4 3703.8 - 2.47E+06 - - - 0.1285 - 4.528 0.592 - 1013.3 1 2 0 0.0003 24 0 0 0 1.45E+07 7.90E+06 - - - 8.6479 0.996 221125_WJC_METTL3_EV_vs_WT_F03.23803.23803.3 5.33E-10 16/84 R.LSFTSVGSITSGYSQSSQVFGR.S sp|P07196|NFL_HUMAN 1 2294.1179 0.66 38270 23803 3 2294.115103 765.7132 Neurofilament light polypeptide OS=Homo sapiens OX=9606 GN=NEFL PE=1 SV=3 8.75 3703.9 - 5.03E+06 - - - -1.2148 - 3.073 0.111 - 211.3 1 2 0 -0.0028 22 0 0 0 5.06E+07 7.63E+07 - - - 2.4384 1 221125_WJC_METTL3_EV_vs_WT_F03.23804.23804.3 1.26E-06 18/88 R.YSVSSPNSLGVVPYLGGEQSYYR.A sp|Q12948|FOXC1_HUMAN 1 2521.2125 2.26 38271 23804 3 2521.212812 841.4114 Forkhead box protein C1 OS=Homo sapiens OX=9606 GN=FOXC1 PE=1 SV=3 6 3703.9 - 2.69E+06 - - - 0.1162 - 3.386 0.563 - 153.5 1 2 0 0.0003 23 0 0 0 5.07E+07 2.24E+07 - - - 7.678 0.9213 221125_WJC_METTL3_EV_vs_WT_F03.23806.23806.3 3.41E-08 15/92 K.YIAENGTDPINNQPLSEEQLIDIK.V "sp|Q9UMS4|PRP19_HUMAN,tr|F5GY56|F5GY56_HUMAN" 2 2713.3447 -1 38273 23806 3 2714.32324 905.4555 Pre-mRNA-processing factor 19 OS=Homo sapiens OX=9606 GN=PRPF19 PE=1 SV=1 3.83 3704.1 - 1.48E+06 - - - 360.656 - 2.799 0.564 - 191.3 1 2 0 0.9786 24 0 0 0 0.00E+00 0.00E+00 - - - 6.9475 1 221125_WJC_METTL3_EV_vs_WT_F03.23807.23807.3 7.92E-09 20/56 R.DLQGLTVEHAIDSFR.E sp|O43290|SNUT1_HUMAN 1 1699.8529 2.53 38274 23807 3 1699.853601 567.6249 U4\U6.U5 tri-snRNP-associated protein 1 OS=Homo sapiens OX=9606 GN=SART1 PE=1 SV=1 4.54 3704.2 - 1.20E+06 - - - 0.3836 - 3.504 0.507 - 463.7 1 2 0 0.0007 15 0 0 0 3.41E+07 1.35E+07 - - - 7.4643 1 221125_WJC_METTL3_EV_vs_WT_F03.23809.23809.4 4.97E-09 22/102 R.VC[160.03]APEETTFHLLHLSLMR[166.11].E "sp|Q8IZH2|XRN1_HUMAN,tr|C9JCZ8|C9JCZ8_HUMAN" 2 2163.0844 1.69 38276 23809 4 2163.084445 541.7784 5'-3' exoribonuclease 1 OS=Homo sapiens OX=9606 GN=XRN1 PE=1 SV=1 6 3704.5 - 851262 - - - 0.0042 - 3.848 0.577 - 556.8 1 2 0 0 18 0 0 0 1.25E+07 7.41E+06 - - - 4.7098 0.9998 221125_WJC_METTL3_EV_vs_WT_F03.23810.23810.3 4.63E-05 13/56 R.DIILGMEISAPSQQR.Q sp|Q6P2Q9|PRP8_HUMAN 1 1656.8505 1.27 38277 23810 3 1656.84641 553.2908 Pre-mRNA-processing-splicing factor 8 OS=Homo sapiens OX=9606 GN=PRPF8 PE=1 SV=2 4.37 3704.6 - 579722 - - - -2.4722 - 2.491 0.418 - 164 1 2 0 -0.0041 15 0 0 0 3.43E+06 2.70E+06 - - - 5.5807 0.9982 221125_WJC_METTL3_EV_vs_WT_F03.23811.23811.3 0.0394 Dec-64 K.DPNEPQKPVSAYALFFR.D "sp|O94900|TOX_HUMAN,sp|O94842|TOX4_HUMAN,sp|Q96NM4|TOX2_HUMAN,sp|O15405|TOX3_HUMAN" 4 1977.9949 -1 38278 23811 3 1977.988092 660.3389 Thymocyte selection-associated high mobility group box protein TOX OS=Homo sapiens OX=9606 GN=TOX PE=1 SV=3 6.07 3704.8 - 500142 - - - -3.4227 - 2.355 0.303 - 143.3 1 2 0 -0.0068 17 0 0 0 0.00E+00 0.00E+00 - - - 4.0802 1 221125_WJC_METTL3_EV_vs_WT_F03.23812.23812.2 9.57E-07 13/32 R.NSGSC[160.03]LGGDEIFLLC[160.03]DK[136.11].V "sp|Q04206|TF65_HUMAN,tr|E9PKV4|E9PKV4_HUMAN,tr|A0A087WVP0|A0A087WVP0_HUMAN,tr|A0A087X0W8|A0A087X0W8_HUMAN,tr|E9PKH5|E9PKH5_HUMAN,tr|Q2TAM5|Q2TAM5_HUMAN" 6 1891.8536 0.001 38279 23812 2 1891.850977 946.9341 Transcription factor p65 OS=Homo sapiens OX=9606 GN=RELA PE=1 SV=2 4.03 3704.9 - 489572 - - - -1.36 - 2.974 0.608 - 499.3 1 2 0 -0.0026 17 0 0 0 0.00E+00 3.55E+06 - - - 6.2105 0.9999 221125_WJC_METTL3_EV_vs_WT_F03.23813.23813.4 0.00119 14/90 K.YVPAIAHLIHSLNPVR.E "sp|Q9H3G5|CPVL_HUMAN,tr|C9JLV0|C9JLV0_HUMAN" 2 1799.0206 1.05 38280 23813 4 1799.020716 450.7624 Probable serine carboxypeptidase CPVL OS=Homo sapiens OX=9606 GN=CPVL PE=1 SV=2 8.76 3705 - 487138 - - - 0.0517 - 2.867 0.429 - 89.3 1 2 0 0.0001 16 0 0 0 3.87E+06 3.67E+06 - - - 3.331 0.9999 221125_WJC_METTL3_EV_vs_WT_F03.23814.23814.3 1.16E-08 15/56 K.NKDDLTPLLLAVSGK.K "sp|Q9UPS8|ANR26_HUMAN,tr|A0A6Q8PHI6|A0A6Q8PHI6_HUMAN,tr|A0A6Q8PF30|A0A6Q8PF30_HUMAN,tr|A0A6Q8PHK2|A0A6Q8PHK2_HUMAN,tr|A0A6Q8PH02|A0A6Q8PH02_HUMAN,tr|A0A6Q8PHK8|A0A6Q8PHK8_HUMAN,tr|E7ESJ3|E7ESJ3_HUMAN" 7 1582.893 3.28 38281 23814 3 1582.892704 528.6383 Ankyrin repeat domain-containing protein 26 OS=Homo sapiens OX=9606 GN=ANKRD26 PE=1 SV=4 5.96 3705.2 - 371652 - - - -0.2015 - 2.704 0.571 - 332.4 1 2 1 -0.0003 15 0 0 0 4.74E+06 1.44E+06 - - - 7.5016 1 221125_WJC_METTL3_EV_vs_WT_F03.23818.23818.3 1.93E-07 17/84 R.AITVFSPDGHLFQVEYAQEAVK[136.11].K "sp|Q8TAA3|PSMA8_HUMAN,sp|O14818|PSA7_HUMAN,tr|F5GY34|F5GY34_HUMAN" 3 2456.2467 0.73 38282 23818 3 2456.249815 819.7562 Proteasome subunit alpha-type 8 OS=Homo sapiens OX=9606 GN=PSMA8 PE=2 SV=3 4.65 3705.7 - 3.04E+06 - - - 1.2576 - 3.911 0.578 - 269.5 1 2 0 0.0031 22 0 0 0 1.32E+07 1.81E+07 - - - 8.2166 0.9999 221125_WJC_METTL3_EV_vs_WT_F03.23820.23820.4 4.63E-06 19/138 R.FLEQQNQVLQTKWELLQQVDTSTR.T sp|P04264|K2C1_HUMAN 1 2931.509 0.12 38284 23820 4 2931.509454 733.8845 "Keratin, type II cytoskeletal 1 OS=Homo sapiens OX=9606 GN=KRT1 PE=1 SV=6" 4.68 3705.8 - 3.46E+06 - - - 0.1426 - 3.116 0.536 - 197 1 2 1 0.0004 24 0 0 0 1.01E+07 8.64E+07 - - - 4.256 1 221125_WJC_METTL3_EV_vs_WT_F03.23822.23822.3 2.11E-09 20/84 R.AITVFSPDGHLFQVEYAQEAVK.K "sp|Q8TAA3|PSMA8_HUMAN,sp|O14818|PSA7_HUMAN,tr|F5GY34|F5GY34_HUMAN" 3 2448.2325 0.73 38286 23822 3 2448.238697 817.0848 Proteasome subunit alpha-type 8 OS=Homo sapiens OX=9606 GN=PSMA8 PE=2 SV=3 4.65 3705.9 - 2.47E+06 - - - 2.5206 - 3.785 0.557 - 420.2 1 2 0 0.0062 22 0 0 0 1.32E+07 1.81E+07 - - - 7.904 1 221125_WJC_METTL3_EV_vs_WT_F03.23823.23823.3 7.53E-12 26/88 R.YSVSSPNSLGVVPYLGGEQSYYR[166.11].A sp|Q12948|FOXC1_HUMAN 1 2531.2208 2.38 38287 23823 3 2531.228061 844.7475 Forkhead box protein C1 OS=Homo sapiens OX=9606 GN=FOXC1 PE=1 SV=3 6 3706 - 2.37E+06 - - - 2.8729 - 4.257 0.658 - 518.6 1 2 0 0.0073 23 0 0 0 5.07E+07 2.12E+07 - - - 9.2723 1 221125_WJC_METTL3_EV_vs_WT_F03.23824.23824.2 1.61E-07 15/26 R.GFAFVTFESPADAK.A "sp|O75526|RMXL2_HUMAN,sp|Q96E39|RMXL1_HUMAN,sp|Q8N7X1|RMXL3_HUMAN,sp|P38159|RBMX_HUMAN,tr|A0A1B0GUK8|A0A1B0GUK8_HUMAN,tr|H3BT71|H3BT71_HUMAN,tr|H0Y6E7|H0Y6E7_HUMAN,tr|H3BR27|H3BR27_HUMAN" 8 1485.714 2.13 38288 23824 2 1485.714381 743.8643 "RNA-binding motif protein, X-linked-like-2 OS=Homo sapiens OX=9606 GN=RBMXL2 PE=1 SV=3" 4.37 3706.1 - 1.79E+06 - - - 0.2591 - 2.836 0.614 - 807.9 1 2 0 0.0004 14 0 0 0 2.19E+07 1.03E+07 - - - 6.1917 0.9998 221125_WJC_METTL3_EV_vs_WT_F03.23826.23826.2 5.76E-06 17/28 R.DDGTGQLLLPLSDAR.K "sp|Q15149|PLEC_HUMAN,tr|H0YDN1|H0YDN1_HUMAN" 2 1569.7999 1.78 38290 23826 2 1569.797576 785.9072 Plectin OS=Homo sapiens OX=9606 GN=PLEC PE=1 SV=3 3.93 3706.4 - 1.16E+06 - - - -1.4492 - 2.463 0.522 - 825.8 1 2 0 -0.0023 15 0 0 0 6.85E+06 3.84E+06 - - - 5.1119 1 221125_WJC_METTL3_EV_vs_WT_F03.23827.23827.3 7.18E-12 24/88 R.TQIAPGSQTVLGIGPGPADLIDK.V "sp|Q9Y3E5|PTH2_HUMAN,tr|J3KQ48|J3KQ48_HUMAN" 2 2247.2111 1.06 38291 23827 3 2247.220786 750.0776 "Peptidyl-tRNA hydrolase 2, mitochondrial OS=Homo sapiens OX=9606 GN=PTRH2 PE=1 SV=1" 4.21 3706.5 - 1.04E+06 - - - 4.3267 - 4.514 0.591 - 611 1 2 0 0.0097 23 0 0 0 1.05E+07 9.90E+06 - - - 8.6621 0.9997 221125_WJC_METTL3_EV_vs_WT_F03.23829.23829.2 6.62E-05 28-Oct K.LDLQQGQNLLQGLSK[136.11].L "sp|Q9HCE1|MOV10_HUMAN,tr|Q5JR04|Q5JR04_HUMAN" 2 1661.9192 0.98 38293 23829 2 1661.921406 831.9669 Helicase MOV-10 OS=Homo sapiens OX=9606 GN=MOV10 PE=1 SV=2 5.84 3706.8 - 832992 - - - 1.337 - 2.205 0.429 - 240.4 1 2 0 0.0022 15 0 0 0 5.17E+06 5.25E+06 - - - 4.1529 1 221125_WJC_METTL3_EV_vs_WT_F03.23830.23830.3 6.06E-17 22/124 R.C[160.03]FGFVTYSNVEEADAAMAASPHAVDGNTVELK.R sp|Q13151|ROA0_HUMAN 1 3399.5388 -1 38294 23830 3 3399.53901 1134.1869 Heterogeneous nuclear ribonucleoprotein A0 OS=Homo sapiens OX=9606 GN=HNRNPA0 PE=1 SV=1 4.17 3706.9 - 820425 - - - 0.0741 - 4.419 0.754 - 320.8 1 2 0 0.0003 32 0 0 0 0.00E+00 0.00E+00 - - - 10.3648 0.9998 221125_WJC_METTL3_EV_vs_WT_F03.23835.23835.3 0.000449 Sep-48 R.NLANTVTEEILEK[136.11].A "sp|O60506|HNRPQ_HUMAN,tr|A0A7I2YQV8|A0A7I2YQV8_HUMAN,tr|A0A7I2YQN2|A0A7I2YQN2_HUMAN,tr|A0A7I2V4Z0|A0A7I2V4Z0_HUMAN,tr|B7Z645|B7Z645_HUMAN,tr|A0A7I2V2F2|A0A7I2V2F2_HUMAN,tr|A0A7I2V346|A0A7I2V346_HUMAN,tr|A0A7I2V309|A0A7I2V309_HUMAN" 8 1480.7864 2.39 38299 23835 3 1480.786618 494.6028 Heterogeneous nuclear ribonucleoprotein Q OS=Homo sapiens OX=9606 GN=SYNCRIP PE=1 SV=2 4.25 3707.6 - 284463 - - - 0.1209 - 2.047 0.355 - 121.2 1 2 0 0.0002 13 0 0 0 4.29E+06 1.79E+06 - - - 4.4402 1 221125_WJC_METTL3_EV_vs_WT_F03.23840.23840.3 0.00309 18/56 R.DLQGLTVEHAIDSFR[166.11].E sp|O43290|SNUT1_HUMAN 1 1709.8612 2.53 38303 23840 3 1709.861418 570.961 U4\U6.U5 tri-snRNP-associated protein 1 OS=Homo sapiens OX=9606 GN=SART1 PE=1 SV=1 4.54 3708 - 2.97E+06 - - - 0.1164 - 3.425 0.452 - 353.7 1 2 0 0.0002 15 0 0 0 3.41E+07 1.35E+07 - - - 6.7917 1 221125_WJC_METTL3_EV_vs_WT_F03.23841.23841.2 0.000172 15/26 V.SQEILELLNTTTAK[136.11].E "sp|Q86U44|MTA70_HUMAN,tr|H0YFV6|H0YFV6_HUMAN" 2 1567.8549 0.01 38304 23841 2 1567.856684 784.9347 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 4.53 3708 - 2.00E+06 - - - 1.1678 - 2.978 0.553 - 773.8 1 1 0 0.0018 14 0 0 0 2.27E+05 3.79E+07 - - - 5.8633 1 221125_WJC_METTL3_EV_vs_WT_F03.23842.23842.3 3.85E-10 21/80 K.VWYEWAVTAPVC[160.03]SAIHNPTGR.S "sp|O14744|ANM5_HUMAN,tr|H7BZ44|H7BZ44_HUMAN" 2 2413.1637 7.09 38305 23842 3 2413.158492 805.3952 Protein arginine N-methyltransferase 5 OS=Homo sapiens OX=9606 GN=PRMT5 PE=1 SV=4 6.71 3708.1 - 1.65E+06 - - - -2.1727 - 4.088 0.649 - 541.6 1 2 0 -0.0052 21 0 0 0 2.35E+07 3.31E+06 - - - 9.15 0.9975 221125_WJC_METTL3_EV_vs_WT_F03.23844.23844.2 0.00257 15/32 K.EFLPEGQDIGAFVAEQK.V "sp|Q04637|IF4G1_HUMAN,tr|H7C0V6|H7C0V6_HUMAN,tr|E7EUU4|E7EUU4_HUMAN,tr|E9PGM1|E9PGM1_HUMAN,tr|E7EX73|E7EX73_HUMAN,tr|A0A7I2Y1C3|A0A7I2Y1C3_HUMAN" 6 1876.9207 3.99 38307 23844 2 1876.921974 939.4676 Eukaryotic translation initiation factor 4 gamma 1 OS=Homo sapiens OX=9606 GN=EIF4G1 PE=1 SV=4 4 3708.3 - 1.21E+06 - - - 0.682 - 2.412 0.07 - 505.6 1 2 0 0.0013 17 0 0 0 1.57E+07 3.92E+06 - - - 1.7223 0.9986 221125_WJC_METTL3_EV_vs_WT_F03.23845.23845.3 1.43E-09 17/52 V.SQEILELLNTTTAK[136.11].E "sp|Q86U44|MTA70_HUMAN,tr|H0YFV6|H0YFV6_HUMAN" 2 1567.8549 4.28 38308 23845 3 1567.855174 523.6256 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 4.53 3708.4 - 1.15E+06 - - - 0.2047 - 3.123 0.555 - 464.8 1 1 0 0.0003 14 0 0 0 7.49E+07 1.75E+07 - - - 7.754 0.9999 221125_WJC_METTL3_EV_vs_WT_F03.23849.23849.3 0.000287 14/72 K.QVSSLSSGVIQEALATNMK.L "sp|Q9UPN3|MACF1_HUMAN,tr|H3BQK9|H3BQK9_HUMAN,tr|A0A7P0MQR8|A0A7P0MQR8_HUMAN,tr|H0Y390|H0Y390_HUMAN,tr|H3BPE1|H3BPE1_HUMAN,tr|A0A590UJG2|A0A590UJG2_HUMAN" 6 1962.0092 0.5 38312 23849 3 1962.00837 655.0103 "Microtubule-actin cross-linking factor 1, isoforms 1\2\3\5 OS=Homo sapiens OX=9606 GN=MACF1 PE=1 SV=4" 6 3708.9 - 328032 - - - -0.419 - 2.803 0.399 - 240.6 1 2 0 -0.0008 19 0 0 0 4.02E+06 8.01E+06 - - - 5.5204 1 221125_WJC_METTL3_EV_vs_WT_F03.23853.23853.3 3.58E-08 16/72 R.YVQLPADEVDTQLLQDAAR.K sp|Q9Y333|LSM2_HUMAN 1 2144.075 5.68 38314 23853 3 2144.078581 715.6989 U6 snRNA-associated Sm-like protein LSm2 OS=Homo sapiens OX=9606 GN=LSM2 PE=1 SV=1 3.84 3709.4 - 4.24E+06 - - - 1.6874 - 3.111 0.572 - 304.2 1 2 0 0.0036 19 0 0 0 2.35E+07 4.14E+06 - - - 7.7046 0.9999 221125_WJC_METTL3_EV_vs_WT_F03.23858.23858.3 1.74E-05 Aug-60 R.THNGESVSYLFSHVPL.- "sp|P60891|PRPS1_HUMAN,sp|P11908|PRPS2_HUMAN,sp|P21108|PRPS3_HUMAN,tr|A0A6Q8PG31|A0A6Q8PG31_HUMAN,tr|B1ALA9|B1ALA9_HUMAN,tr|H7C540|H7C540_HUMAN,tr|A0A0B4J207|A0A0B4J207_HUMAN" 7 1785.8686 - 38319 23858 3 1785.869632 596.2968 Ribose-phosphate pyrophosphokinase 1 OS=Homo sapiens OX=9606 GN=PRPS1 PE=1 SV=2 5.92 3709.7 - 1.80E+06 - - - 0.5784 - 1.735 0.512 - 44.8 1 2 0 0.001 16 0 0 0 - - - - - 5.6618 1 221125_WJC_METTL3_EV_vs_WT_F03.23859.23859.3 8.98E-06 18/52 K.RLDQELDFILSQQK.E "sp|P37198|NUP62_HUMAN,tr|M0QXN5|M0QXN5_HUMAN" 2 1731.9155 2.02 38320 23859 3 1731.918817 578.3125 Nuclear pore glycoprotein p62 OS=Homo sapiens OX=9606 GN=NUP62 PE=1 SV=3 4.56 3709.8 - 1.40E+06 - - - 1.8869 - 3.23 0.564 - 461.1 1 2 0 0.0033 14 0 0 0 1.27E+08 6.29E+07 - - - 7.943 1 221125_WJC_METTL3_EV_vs_WT_F03.23860.23860.2 3.92E-07 17/36 R.YVQLPADEVDTQLLQDAAR.K sp|Q9Y333|LSM2_HUMAN 1 2144.075 6.75 38321 23860 2 2144.081879 1073.0448 U6 snRNA-associated Sm-like protein LSm2 OS=Homo sapiens OX=9606 GN=LSM2 PE=1 SV=1 3.84 3709.9 - 1.33E+06 - - - 3.2256 - 3.41 0.624 - 585.8 1 2 0 0.0069 19 0 0 0 7.43E+06 1.10E+06 - - - 6.6636 0.9996 221125_WJC_METTL3_EV_vs_WT_F03.23861.23861.3 0.00286 16/52 R.DKWLAPDGLIFPDR.A "sp|Q99873|ANM1_HUMAN,tr|E9PQ98|E9PQ98_HUMAN,tr|E9PKG1|E9PKG1_HUMAN,tr|E9PNR9|E9PNR9_HUMAN,tr|H0YDE4|H0YDE4_HUMAN,tr|E9PIX6|E9PIX6_HUMAN" 6 1641.8515 2.15 38322 23861 3 1641.851787 548.2911 Protein arginine N-methyltransferase 1 OS=Homo sapiens OX=9606 GN=PRMT1 PE=1 SV=3 4.43 3710 - 1.11E+06 - - - 0.1797 - 2.432 0.399 - 388.3 1 2 1 0.0003 14 0 0 0 4.51E+08 2.10E+08 - - - 5.3502 0.9943 221125_WJC_METTL3_EV_vs_WT_F03.23863.23863.3 0.00163 Oct-64 K.EFLPEGQDIGAFVAEQK[136.11].V "sp|Q04637|IF4G1_HUMAN,tr|H7C0V6|H7C0V6_HUMAN,tr|E7EUU4|E7EUU4_HUMAN,tr|E9PGM1|E9PGM1_HUMAN,tr|E7EX73|E7EX73_HUMAN,tr|A0A7I2Y1C3|A0A7I2Y1C3_HUMAN" 6 1884.9349 6.9 38324 23863 3 1884.942479 629.3189 Eukaryotic translation initiation factor 4 gamma 1 OS=Homo sapiens OX=9606 GN=EIF4G1 PE=1 SV=4 4 3710.2 - 1.06E+06 - - - 4.024 - 1.913 0.304 - 101.3 1 2 0 0.0076 17 0 0 0 3.95E+07 5.73E+06 - - - 3.5659 0.9862 221125_WJC_METTL3_EV_vs_WT_F03.23864.23864.3 0.00134 Oct-80 K.VVLNMNLTPTQGSYTFDPVTK[136.11].V sp|Q9Y2T2|AP3M1_HUMAN 1 2332.1864 1.81 38325 23864 3 2333.189436 778.4028 AP-3 complex subunit mu-1 OS=Homo sapiens OX=9606 GN=AP3M1 PE=1 SV=1 5.81 3710.3 - 771608 - - - 430.0694 - 2.08 0.331 - 89.5 1 2 0 1.003 21 0 0 0 4.39E+06 2.43E+06 - - - 3.7083 0.9998 221125_WJC_METTL3_EV_vs_WT_F03.23865.23865.3 0.000959 Nov-56 R.FYIAELTC[160.03]AVESVHK.M sp|O95835|LATS1_HUMAN 1 1765.8709 3.2 38326 23865 3 1765.870421 589.6309 Serine\threonine-protein kinase LATS1 OS=Homo sapiens OX=9606 GN=LATS1 PE=1 SV=1 5.4 3710.4 - 658109 - - - -0.2752 - 2.068 0.365 - 80.9 1 2 0 -0.0005 15 0 0 0 4.41E+06 1.38E+06 - - - 4.5052 0.9998 221125_WJC_METTL3_EV_vs_WT_F03.23866.23866.2 0.00338 14/44 R.YSVSSPNSLGVVPYLGGEQSYYR.A sp|Q12948|FOXC1_HUMAN 1 2521.2125 4.05 38327 23866 2 2521.217768 1261.6135 Forkhead box protein C1 OS=Homo sapiens OX=9606 GN=FOXC1 PE=1 SV=3 6 3710.5 - 624318 - - - 2.0819 - 2.679 0.563 - 207.1 1 2 0 0.0052 23 0 0 0 5.44E+06 1.34E+06 - - - 5.6204 1 221125_WJC_METTL3_EV_vs_WT_F03.23869.23869.3 0.000859 16/44 K.GSPIDVLHGLIR.R "tr|A0A669KAV7|A0A669KAV7_HUMAN,tr|M0QXA7|M0QXA7_HUMAN,tr|A0A669KBH9|A0A669KBH9_HUMAN" 3 1275.7299 1.34 38330 23869 3 1275.729873 426.2506 Protein Wiz OS=Homo sapiens OX=9606 GN=WIZ PE=1 SV=1 6.74 3710.9 - 381430 - - - -0.0368 - 2.832 0.44 - 599.9 1 2 0 0 12 0 0 0 1.29E+07 9.65E+06 - - - 6.331 0.9681 221125_WJC_METTL3_EV_vs_WT_F03.23871.23871.3 0.484 13/48 R.MTIGHLIEC[160.03]LQGK.V "sp|P30876|RPB2_HUMAN,tr|C9J4M6|C9J4M6_HUMAN,tr|C9J2Y9|C9J2Y9_HUMAN" 3 1498.7636 -1 38332 23871 3 1498.765248 500.5951 DNA-directed RNA polymerase II subunit RPB2 OS=Homo sapiens OX=9606 GN=POLR2B PE=1 SV=1 6.5 3711.2 - 271199 - - - 1.0962 - 1.447 0.149 - 141.8 1 2 0 0.0016 13 0 0 0 0.00E+00 0.00E+00 - - - 1.2025 1 221125_WJC_METTL3_EV_vs_WT_F03.23876.23876.3 3.78E-05 17/52 K.R[166.11]LDQELDFILSQQK[136.11].E "sp|P37198|NUP62_HUMAN,tr|M0QXN5|M0QXN5_HUMAN" 2 1749.938 2.01 38335 23876 3 1749.937935 584.3199 Nuclear pore glycoprotein p62 OS=Homo sapiens OX=9606 GN=NUP62 PE=1 SV=3 4.56 3711.7 - 3.70E+06 - - - -0.048 - 2.885 0.486 - 451.3 1 2 0 -0.0001 14 0 0 0 1.26E+08 6.29E+07 - - - 6.7741 1 221125_WJC_METTL3_EV_vs_WT_F03.23878.23878.3 2.35E-12 15/96 K.NTELAVFHDETEIQNQTDLLSLSGK[136.11].T "sp|P41252|SYIC_HUMAN,tr|A0A804HL54|A0A804HL54_HUMAN,tr|A0A0A0MSX9|A0A0A0MSX9_HUMAN" 3 2809.3861 1.03 38337 23878 3 2809.385379 937.4693 "Isoleucine--tRNA ligase, cytoplasmic OS=Homo sapiens OX=9606 GN=IARS1 PE=1 SV=2" 4.17 3711.9 - 1.23E+06 - - - -0.2684 - 3.575 0.667 - 202.8 1 2 0 -0.0008 25 0 0 0 2.04E+07 1.98E+07 - - - 8.9071 0.9996 221125_WJC_METTL3_EV_vs_WT_F03.23880.23880.3 4.76E-07 20/80 K.LGQSVTTIPTVGFNVETVTYK[136.11].N sp|P62330|ARF6_HUMAN 1 2261.2035 0.94 38339 23880 3 2261.21526 754.7418 ADP-ribosylation factor 6 OS=Homo sapiens OX=9606 GN=ARF6 PE=1 SV=2 6 3712.1 - 921524 - - - 5.2162 - 3.346 0.491 - 465.8 1 2 0 0.0118 21 0 0 0 2.54E+06 2.70E+06 - - - 6.9065 0.9999 221125_WJC_METTL3_EV_vs_WT_F03.23884.23884.3 5.26E-07 17/84 K.VFVLDEADVMIATQGHQDQSIR[166.11].L "sp|Q9NUU7|DD19A_HUMAN,sp|Q9UMR2|DD19B_HUMAN,tr|F6QDS0|F6QDS0_HUMAN,tr|I3L352|I3L352_HUMAN,tr|H3BN59|H3BN59_HUMAN,tr|H3BQK0|H3BQK0_HUMAN,tr|I3L0H8|I3L0H8_HUMAN" 7 2481.2197 1.06 38343 23884 3 2481.209239 828.0805 ATP-dependent RNA helicase DDX19A OS=Homo sapiens OX=9606 GN=DDX19A PE=1 SV=1 4.22 3712.6 - 632283 - - - -4.2334 - 3.117 0.57 - 243.1 1 2 0 -0.0105 22 0 0 0 5.07E+06 4.80E+06 - - - 7.5874 0.9999 221125_WJC_METTL3_EV_vs_WT_F03.23888.23888.3 3.62E-05 14/44 K.GSPIDVLHGLIR[166.11].R "tr|A0A669KAV7|A0A669KAV7_HUMAN,tr|M0QXA7|M0QXA7_HUMAN,tr|A0A669KBH9|A0A669KBH9_HUMAN" 3 1285.7382 1.34 38347 23888 3 1285.738145 429.5867 Protein Wiz OS=Homo sapiens OX=9606 GN=WIZ PE=1 SV=1 6.74 3713.1 - 430066 - - - -0.035 - 2.323 0.397 - 297.6 1 2 0 0 12 0 0 0 1.29E+07 9.65E+06 - - - 5.3024 1 221125_WJC_METTL3_EV_vs_WT_F03.23895.23895.3 2.16E-05 16/68 K.DNHLLGTFDLTGIPPAPR[166.11].G "sp|P11021|BIP_HUMAN,tr|A0A7P0TAI0|A0A7P0TAI0_HUMAN" 2 1943.014 0.72 38352 23895 3 1943.0156 648.6786 Endoplasmic reticulum chaperone BiP OS=Homo sapiens OX=9606 GN=HSPA5 PE=1 SV=2 5.21 3713.9 - 4.72E+06 - - - 0.8075 - 3.197 0.487 - 221.1 1 2 0 0.0016 18 0 0 0 1.28E+08 1.77E+08 - - - 6.8632 1 221125_WJC_METTL3_EV_vs_WT_F03.23897.23897.2 3.22E-13 20/34 R.SAAEMYGSSFDLDYDFQR.D "tr|G3V251|G3V251_HUMAN,tr|B4DY08|B4DY08_HUMAN,tr|G3V3K6|G3V3K6_HUMAN,tr|B2R5W2|B2R5W2_HUMAN,tr|G3V4C1|G3V4C1_HUMAN,tr|G3V2D6|G3V2D6_HUMAN,tr|G3V5X6|G3V5X6_HUMAN,tr|G3V4W0|G3V4W0_HUMAN" 8 2100.8735 1.48 38354 23897 2 2100.870934 1051.444 Heterogeneous nuclear ribonucleoproteins C1\C2 (Fragment) OS=Homo sapiens OX=9606 GN=HNRNPC PE=1 SV=1 3.84 3714 - 2.09E+06 - - - -1.2147 - 3.914 0.737 - 1584.4 1 2 0 -0.0026 18 0 0 0 1.56E+08 1.05E+08 - - - 7.8385 1 221125_WJC_METTL3_EV_vs_WT_F03.23898.23898.3 3.92E-08 16/52 R.SLHDALC[160.03]VLAQTVK[136.11].D "sp|P78371|TCPB_HUMAN,tr|F8VQ14|F8VQ14_HUMAN,tr|F5GWF6|F5GWF6_HUMAN" 3 1561.8378 0.48 38355 23898 3 1561.83868 521.6199 T-complex protein 1 subunit beta OS=Homo sapiens OX=9606 GN=CCT2 PE=1 SV=4 6.46 3714 - 1.55E+06 - - - 0.5871 - 3.128 0.508 - 482.3 1 2 0 0.0009 14 0 0 0 1.87E+08 3.92E+08 - - - 7.2341 0.9996 221125_WJC_METTL3_EV_vs_WT_F03.23900.23900.3 6.05E-08 17/80 R.NPPGFAFVEFEDPR[166.11]DAEDAVR[166.11].G "sp|Q16629|SRSF7_HUMAN,tr|C9JAB2|C9JAB2_HUMAN,tr|A0A0B4J1Z1|A0A0B4J1Z1_HUMAN" 3 2397.114 2 38357 23900 3 2397.114291 800.0453 Serine\arginine-rich splicing factor 7 OS=Homo sapiens OX=9606 GN=SRSF7 PE=1 SV=1 4.02 3714.3 - 967376 - - - 0.1093 - 2.787 0.393 - 164.5 1 2 1 0.0003 21 0 0 0 3.76E+08 1.87E+08 - - - 5.3788 0.9601 221125_WJC_METTL3_EV_vs_WT_F03.23902.23902.3 0.00945 14/72 K.SSNYVLTDEQSLWIEDTTK[136.11].S "sp|Q96FV9|THOC1_HUMAN,tr|A0A087WWS1|A0A087WWS1_HUMAN,tr|A0A087WY84|A0A087WY84_HUMAN,tr|R4GMN4|R4GMN4_HUMAN" 4 2236.0627 0.23 38359 23902 3 2237.067362 746.3615 THO complex subunit 1 OS=Homo sapiens OX=9606 GN=THOC1 PE=1 SV=1 3.92 3714.5 - 741742 - - - 449.3112 - 2.373 0.236 - 221.1 1 2 0 1.0047 19 0 0 0 3.43E+06 1.49E+07 - - - 3.0159 1 221125_WJC_METTL3_EV_vs_WT_F03.23906.23906.3 2.18E-08 19/52 R.SLHDALC[160.03]VLAQTVK.D "sp|P78371|TCPB_HUMAN,tr|F8VQ14|F8VQ14_HUMAN,tr|F5GWF6|F5GWF6_HUMAN" 3 1553.8236 0.48 38363 23906 3 1553.824618 518.9485 T-complex protein 1 subunit beta OS=Homo sapiens OX=9606 GN=CCT2 PE=1 SV=4 6.46 3715 - 579731 - - - 0.679 - 3.151 0.545 - 675.9 1 2 0 0.0011 14 0 0 0 1.87E+08 3.93E+08 - - - 7.666 1 221125_WJC_METTL3_EV_vs_WT_F03.23913.23913.3 1.53E-05 17/68 K.DNHLLGTFDLTGIPPAPR.G "sp|P11021|BIP_HUMAN,tr|A0A7P0TAI0|A0A7P0TAI0_HUMAN" 2 1933.0058 0.72 38368 23913 3 1933.004133 645.3425 Endoplasmic reticulum chaperone BiP OS=Homo sapiens OX=9606 GN=HSPA5 PE=1 SV=2 5.21 3715.7 - 3.97E+06 - - - -0.8422 - 2.982 0.539 - 246.4 1 2 0 -0.0016 18 0 0 0 1.28E+08 1.76E+08 - - - 7.2695 1 221125_WJC_METTL3_EV_vs_WT_F03.23914.23914.3 5.33E-14 19/72 K.LGGSLADSYLDEGFLLDK[136.11]K[136.11].L "sp|P78371|TCPB_HUMAN,tr|F8VQ14|F8VQ14_HUMAN,tr|F5GWF6|F5GWF6_HUMAN" 3 2056.0699 0.45 38369 23914 3 2056.071233 686.3639 T-complex protein 1 subunit beta OS=Homo sapiens OX=9606 GN=CCT2 PE=1 SV=4 4.23 3715.8 - 3.59E+06 - - - 0.6298 - 4.245 0.665 - 558.1 1 2 0 0.0013 19 0 0 0 1.14E+08 2.55E+08 - - - 9.5056 1 221125_WJC_METTL3_EV_vs_WT_F03.23915.23915.3 1.92E-11 33/108 R.QTASVTLQAIAAQNAAVQAVNAHSNILK.A "sp|Q16891|MIC60_HUMAN,tr|B9A067|B9A067_HUMAN,tr|C9J406|C9J406_HUMAN,tr|H7C463|H7C463_HUMAN" 4 2831.5254 1.39 38370 23915 3 2831.526052 944.8491 MICOS complex subunit MIC60 OS=Homo sapiens OX=9606 GN=IMMT PE=1 SV=1 8.76 3715.9 - 2.98E+06 - - - 0.2465 - 5.971 0.601 - 1048 1 2 0 0.0007 28 0 0 0 7.01E+07 5.06E+07 - - - 9.3514 0.9975 221125_WJC_METTL3_EV_vs_WT_F03.23917.23917.2 0.000184 13/26 R.DKWLAPDGLIFPDR.A "sp|Q99873|ANM1_HUMAN,tr|E9PQ98|E9PQ98_HUMAN,tr|E9PKG1|E9PKG1_HUMAN,tr|E9PNR9|E9PNR9_HUMAN,tr|H0YDE4|H0YDE4_HUMAN,tr|E9PIX6|E9PIX6_HUMAN" 6 1641.8515 2.72 38372 23917 2 1641.853964 821.933 Protein arginine N-methyltransferase 1 OS=Homo sapiens OX=9606 GN=PRMT1 PE=1 SV=3 4.43 3716.1 - 1.71E+06 - - - 1.5056 - 2.676 0.44 - 545.2 1 2 1 0.0025 14 0 0 0 7.12E+07 2.62E+07 - - - 4.7602 1 221125_WJC_METTL3_EV_vs_WT_F03.23920.23920.2 3.64E-08 13/26 R.DK[136.11]WLAPDGLIFPDR[166.11].A "sp|Q99873|ANM1_HUMAN,tr|E9PQ98|E9PQ98_HUMAN,tr|E9PKG1|E9PKG1_HUMAN,tr|E9PNR9|E9PNR9_HUMAN,tr|H0YDE4|H0YDE4_HUMAN,tr|E9PIX6|E9PIX6_HUMAN" 6 1659.874 2.71 38375 23920 2 1659.876318 830.9443 Protein arginine N-methyltransferase 1 OS=Homo sapiens OX=9606 GN=PRMT1 PE=1 SV=3 4.43 3716.5 - 944929 - - - 1.4194 - 3.063 0.543 - 499.2 1 2 1 0.0024 14 0 0 0 7.10E+07 2.62E+07 - - - 5.8599 0.9982 221125_WJC_METTL3_EV_vs_WT_F03.23921.23921.3 0.0623 Oct-48 R.NVDPFHIYFC[160.03]NLK[136.11].L "sp|Q7L0Y3|TM10C_HUMAN,tr|C9JVB6|C9JVB6_HUMAN" 2 1673.8115 0.7 38376 23921 3 1673.810465 558.9445 tRNA methyltransferase 10 homolog C OS=Homo sapiens OX=9606 GN=TRMT10C PE=1 SV=2 6.73 3716.6 - 820235 - - - -0.647 - 1.765 0.254 - 100.9 1 2 0 -0.0011 13 0 0 0 5.59E+06 8.01E+06 - - - 2.912 0.9999 221125_WJC_METTL3_EV_vs_WT_F03.23923.23923.4 0.000113 16/114 K.ISNIVHISNLVR[166.11]PFTLGQLK[136.11].E "sp|Q9UKV3|ACINU_HUMAN,tr|G3V3B0|G3V3B0_HUMAN,tr|S4R3H4|S4R3H4_HUMAN,tr|E7EQT4|E7EQT4_HUMAN" 4 2266.328 1.26 38378 23923 4 2266.327637 567.5893 Apoptotic chromatin condensation inducer in the nucleus OS=Homo sapiens OX=9606 GN=ACIN1 PE=1 SV=2 11 3716.9 - 621802 - - - -0.1787 - 2.777 0.421 - 175.3 1 2 0 -0.0004 20 0 0 0 7.00E+06 5.55E+06 - - - 3.2317 1 221125_WJC_METTL3_EV_vs_WT_F03.23927.23927.2 4.40E-13 18/34 R.SAAEMYGSSFDLDYDFQR[166.11].D "tr|G3V251|G3V251_HUMAN,tr|B4DY08|B4DY08_HUMAN,tr|G3V3K6|G3V3K6_HUMAN,tr|B2R5W2|B2R5W2_HUMAN,tr|G3V4C1|G3V4C1_HUMAN,tr|G3V2D6|G3V2D6_HUMAN,tr|G3V5X6|G3V5X6_HUMAN,tr|G3V4W0|G3V4W0_HUMAN" 8 2110.8818 1.48 38380 23927 2 2110.879182 1056.4482 Heterogeneous nuclear ribonucleoproteins C1\C2 (Fragment) OS=Homo sapiens OX=9606 GN=HNRNPC PE=1 SV=1 3.84 3717.4 - 7.35E+06 - - - -1.2194 - 3.726 0.74 - 1248.9 1 2 0 -0.0026 18 0 0 0 1.56E+08 1.05E+08 - - - 7.7396 1 221125_WJC_METTL3_EV_vs_WT_F03.23928.23928.4 2.06E-05 27/162 R.QTASVTLQAIAAQNAAVQAVNAHSNILK.A "sp|Q16891|MIC60_HUMAN,tr|B9A067|B9A067_HUMAN,tr|C9J406|C9J406_HUMAN,tr|H7C463|H7C463_HUMAN" 4 2831.5254 1.39 38381 23928 4 2831.524843 708.8886 MICOS complex subunit MIC60 OS=Homo sapiens OX=9606 GN=IMMT PE=1 SV=1 8.76 3717.4 - 7.87E+06 - - - -0.1805 - 5.757 0.497 - 578.3 1 2 0 -0.0005 28 0 0 0 4.49E+07 3.24E+07 - - - 4.0952 0.922 221125_WJC_METTL3_EV_vs_WT_F03.23930.23930.3 0.000157 21/68 K.ISSIQSIVPALEIANAHR.K "sp|P10809|CH60_HUMAN,tr|A0A7I2V2X6|A0A7I2V2X6_HUMAN,tr|A0A7I2YQK6|A0A7I2YQK6_HUMAN,tr|A0A7I2V599|A0A7I2V599_HUMAN,tr|A0A7I2YQ71|A0A7I2YQ71_HUMAN,tr|A0A7I2V5M1|A0A7I2V5M1_HUMAN,tr|A0A7I2V5K3|A0A7I2V5K3_HUMAN,tr|A0A7I2V369|A0A7I2V369_HUMAN" 8 1918.0636 1.78 38383 23930 3 1919.054787 640.3618 "60 kDa heat shock protein, mitochondrial OS=Homo sapiens OX=9606 GN=HSPD1 PE=1 SV=2" 6.75 3717.6 - 2.25E+06 - - - 516.7592 - 2.737 0.427 - 383.6 1 2 0 0.9912 18 0 0 0 2.19E+07 1.23E+07 - - - 5.5333 1 221125_WJC_METTL3_EV_vs_WT_F03.23931.23931.3 3.28E-07 22/68 H.IFASFNDTFVHVTDLSGK[136.11].E "sp|P62263|RS14_HUMAN,tr|A0A2R8Y811|A0A2R8Y811_HUMAN,tr|E5RH77|E5RH77_HUMAN" 3 2005.0036 0.77 38384 23931 3 2005.003778 669.3418 40S ribosomal protein S14 OS=Homo sapiens OX=9606 GN=RPS14 PE=1 SV=3 5.21 3717.7 - 1.77E+06 - - - 0.0678 - 3.892 0.594 - 534 1 1 0 0.0001 18 0 0 0 2.29E+07 2.98E+07 - - - 8.5463 0.9987 221125_WJC_METTL3_EV_vs_WT_F03.23932.23932.3 1.66E-11 25/92 T.GGAVFGEEGLTLNLEDVQPHDLGK.V "sp|P10809|CH60_HUMAN,tr|A0A7I2V2X6|A0A7I2V2X6_HUMAN,tr|A0A7I2YQK6|A0A7I2YQK6_HUMAN,tr|A0A7I2V599|A0A7I2V599_HUMAN" 4 2494.234 1.44 38385 23932 3 2494.235442 832.4186 "60 kDa heat shock protein, mitochondrial OS=Homo sapiens OX=9606 GN=HSPD1 PE=1 SV=2" 4.17 3717.8 - 1.69E+06 - - - 0.5849 - 3.545 0.574 - 513.8 1 1 0 0.0015 24 0 0 0 3.32E+07 2.31E+07 - - - 7.8785 0.999 221125_WJC_METTL3_EV_vs_WT_F03.23934.23934.3 5.08E-06 14/40 K.DLVTSLK[136.11]DYIK[136.11].A sp|P13674|P4HA1_HUMAN 1 1309.7464 1.59 38387 23934 3 1309.746093 437.5894 Prolyl 4-hydroxylase subunit alpha-1 OS=Homo sapiens OX=9606 GN=P4HA1 PE=1 SV=2 5.96 3718.1 - 1.26E+06 - - - -0.2481 - 2.522 0.295 - 225 1 2 1 -0.0003 11 0 0 0 4.84E+07 3.04E+07 - - - 4.4568 0.9996 221125_WJC_METTL3_EV_vs_WT_F03.23935.23935.3 8.72E-05 13/40 K.DLVTSLKDYIK.A sp|P13674|P4HA1_HUMAN 1 1293.718 1.59 38388 23935 3 1293.717713 432.2466 Prolyl 4-hydroxylase subunit alpha-1 OS=Homo sapiens OX=9606 GN=P4HA1 PE=1 SV=2 5.96 3718.2 - 1.25E+06 - - - -0.2358 - 2.81 0.357 - 181.7 1 2 1 -0.0003 11 0 0 0 4.84E+07 3.04E+07 - - - 5.4552 0.9999 221125_WJC_METTL3_EV_vs_WT_F03.23937.23937.2 5.38E-06 Nov-32 K.ETQVILLDTPGIISPGK[136.11].Q "sp|O75616|ERAL1_HUMAN,tr|J3QSB2|J3QSB2_HUMAN,tr|J3QRV9|J3QRV9_HUMAN" 3 1788.0124 0.75 38390 23937 2 1788.011482 895.0135 "GTPase Era, mitochondrial OS=Homo sapiens OX=9606 GN=ERAL1 PE=1 SV=2" 4.37 3718.4 - 327567 - - - -0.5224 - 2.47 0.458 - 385.2 1 2 0 -0.0009 17 0 0 0 3.99E+06 5.33E+06 - - - 4.6466 0.9999 221125_WJC_METTL3_EV_vs_WT_F03.23939.23939.2 0.000587 26-Nov K.NISFTVWDVGGQDK.L "sp|P84077|ARF1_HUMAN,sp|P61204|ARF3_HUMAN,tr|F5H423|F5H423_HUMAN,tr|F5H0C7|F5H0C7_HUMAN" 4 1564.7522 1.23 38391 23939 2 1564.752098 783.3834 ADP-ribosylation factor 1 OS=Homo sapiens OX=9606 GN=ARF1 PE=1 SV=2 4.21 3718.6 - 5.47E+06 - - - -0.0473 - 1.931 0.519 - 247.8 1 2 0 -0.0001 14 0 0 0 1.11E+08 8.97E+07 - - - 4.5256 1 221125_WJC_METTL3_EV_vs_WT_F03.23941.23941.3 4.37E-08 16/68 R.SAAEMYGSSFDLDYDFQR.D "tr|G3V251|G3V251_HUMAN,tr|B4DY08|B4DY08_HUMAN,tr|G3V3K6|G3V3K6_HUMAN,tr|B2R5W2|B2R5W2_HUMAN,tr|G3V4C1|G3V4C1_HUMAN,tr|G3V2D6|G3V2D6_HUMAN,tr|G3V5X6|G3V5X6_HUMAN,tr|G3V4W0|G3V4W0_HUMAN" 8 2100.8735 1.74 38392 23941 3 2100.873983 701.2984 Heterogeneous nuclear ribonucleoproteins C1\C2 (Fragment) OS=Homo sapiens OX=9606 GN=HNRNPC PE=1 SV=1 3.84 3718.8 - 1.12E+07 - - - 0.2366 - 3.297 0.619 - 384.1 1 2 0 0.0005 18 0 0 0 1.16E+08 6.67E+07 - - - 8.4118 1 221125_WJC_METTL3_EV_vs_WT_F03.23944.23944.3 7.38E-14 25/108 R.QTASVTLQAIAAQNAAVQAVNAHSNILK[136.11].A "sp|Q16891|MIC60_HUMAN,tr|B9A067|B9A067_HUMAN,tr|C9J406|C9J406_HUMAN,tr|H7C463|H7C463_HUMAN" 4 2839.5396 1.39 38395 23944 3 2839.535569 947.5205 MICOS complex subunit MIC60 OS=Homo sapiens OX=9606 GN=IMMT PE=1 SV=1 8.76 3719 - 7.26E+06 - - - -1.4034 - 4.623 0.667 - 672.9 1 2 0 -0.004 28 0 0 0 7.01E+07 5.06E+07 - - - 9.4977 1 221125_WJC_METTL3_EV_vs_WT_F03.23945.23945.2 1.14E-09 19/26 R.SLHDALC[160.03]VLAQTVK[136.11].D "sp|P78371|TCPB_HUMAN,tr|F8VQ14|F8VQ14_HUMAN,tr|F5GWF6|F5GWF6_HUMAN" 3 1561.8378 0.42 38396 23945 2 1561.834658 781.9262 T-complex protein 1 subunit beta OS=Homo sapiens OX=9606 GN=CCT2 PE=1 SV=4 6.46 3719 - 6.64E+06 - - - -1.988 - 3.787 0.613 - 1266.5 1 2 0 -0.0031 14 0 0 0 5.99E+07 1.42E+08 - - - 6.9092 0.9999 221125_WJC_METTL3_EV_vs_WT_F03.23946.23946.3 9.64E-07 17/52 K.AFVDFLSDEIK[136.11]EER[166.11].K sp|Q07021|C1QBP_HUMAN 1 1714.8533 1.2 38397 23946 3 1714.851696 572.625 "Complement component 1 Q subcomponent-binding protein, mitochondrial OS=Homo sapiens OX=9606 GN=C1QBP PE=1 SV=1" 4.18 3719.1 - 3.27E+06 - - - -0.9272 - 3.73 0.529 - 321.7 1 2 1 -0.0016 14 0 0 0 4.57E+08 3.81E+08 - - - 7.9358 1 221125_WJC_METTL3_EV_vs_WT_F03.23947.23947.2 9.73E-10 21/26 R.SLHDALC[160.03]VLAQTVK.D "sp|P78371|TCPB_HUMAN,tr|F8VQ14|F8VQ14_HUMAN,tr|F5GWF6|F5GWF6_HUMAN" 3 1553.8236 0.42 38398 23947 2 1553.819077 777.9191 T-complex protein 1 subunit beta OS=Homo sapiens OX=9606 GN=CCT2 PE=1 SV=4 6.46 3719.1 - 2.85E+06 - - - -2.8871 - 4.133 0.637 - 1518 1 2 0 -0.0045 14 0 0 0 5.99E+07 1.42E+08 - - - 7.3054 0.9999 221125_WJC_METTL3_EV_vs_WT_F03.23948.23948.3 0.00208 21/52 K.AFVDFLSDEIKEER.K sp|Q07021|C1QBP_HUMAN 1 1696.8308 1.2 38399 23948 3 1696.830909 566.6175 "Complement component 1 Q subcomponent-binding protein, mitochondrial OS=Homo sapiens OX=9606 GN=C1QBP PE=1 SV=1" 4.18 3719.2 - 2.66E+06 - - - 0.0548 - 3.911 0.421 - 514.1 1 2 1 0.0001 14 0 0 0 4.57E+08 3.81E+08 - - - 6.858 1 221125_WJC_METTL3_EV_vs_WT_F03.23950.23950.3 1.63E-10 26/104 K.GLLALGDYMNVQC[160.03]HAC[160.03]IGGTNVGEDIR.K "sp|P38919|IF4A3_HUMAN,tr|I3L3H2|I3L3H2_HUMAN" 2 2932.363 15.41 38401 23950 3 2932.355057 978.4616 Eukaryotic initiation factor 4A-III OS=Homo sapiens OX=9606 GN=EIF4A3 PE=1 SV=4 4.54 3719.4 - 1.40E+06 - - - -2.7026 - 5.013 0.729 - 587 1 2 0 -0.0079 27 0 0 0 1.11E+07 7.18E+05 - - - 10.3741 0.9999 221125_WJC_METTL3_EV_vs_WT_F03.23951.23951.2 4.54E-06 20-Dec R.NPEAALSPTFR[166.11].S "sp|Q86U44|MTA70_HUMAN,tr|B4E349|B4E349_HUMAN,tr|F5H6D8|F5H6D8_HUMAN,tr|B4DTN4|B4DTN4_HUMAN" 4 1211.6174 0.001 38402 23951 2 1211.617764 606.816 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 6 3719.5 - 435193 - - - 0.2946 - 2.623 0.412 - 432.7 1 2 0 0.0004 11 0 0 0 0.00E+00 9.59E+06 - - - 4.6926 0.9663 221125_WJC_METTL3_EV_vs_WT_F03.23958.23958.3 1.17E-08 20/76 K.HAASDVDLEIESLLNQQSTK[136.11].E "sp|Q86U44|MTA70_HUMAN,tr|F5H6D8|F5H6D8_HUMAN,tr|H0YFV6|H0YFV6_HUMAN,tr|B4DTN4|B4DTN4_HUMAN" 4 2205.1005 0.02 38407 23958 3 2206.08542 736.0408 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 4.31 3720.1 - 3.86E+06 - - - 446.6753 - 3.869 0.608 - 465.9 1 2 0 0.985 20 0 0 0 3.12E+06 2.03E+08 - - - 8.3282 0.9999 221125_WJC_METTL3_EV_vs_WT_F03.23959.23959.3 0.000296 22/68 R.VFEVSLADLQNDEVAFRK.F "sp|P61247|RS3A_HUMAN,tr|H0Y8L7|H0Y8L7_HUMAN,tr|D6RI02|D6RI02_HUMAN,tr|D6RED7|D6RED7_HUMAN,tr|D6RGE0|D6RGE0_HUMAN,tr|D6RAS7|D6RAS7_HUMAN,tr|D6RB09|D6RB09_HUMAN,tr|E9PFI5|E9PFI5_HUMAN,tr|D6RAT0|D6RAT0_HUMAN,tr|D6RG13|D6RG13_HUMAN" 10 2079.0637 0.66 38408 23959 3 2079.054797 694.0285 40S ribosomal protein S3a OS=Homo sapiens OX=9606 GN=RPS3A PE=1 SV=2 4.32 3720.2 - 1.84E+06 - - - -4.2678 - 4.188 0.491 - 441.3 1 2 0 -0.0089 18 0 0 0 1.12E+08 1.69E+08 - - - 7.5781 1 221125_WJC_METTL3_EV_vs_WT_F03.23961.23961.2 4.26E-05 17/34 K.EAPETDTSPSLWDVEFAK.Q sp|Q92665|RT31_HUMAN 1 2020.9266 1.87 38410 23961 2 2020.923926 1011.4706 "28S ribosomal protein S31, mitochondrial OS=Homo sapiens OX=9606 GN=MRPS31 PE=1 SV=3" 3.83 3720.5 - 1.36E+06 - - - -1.3068 - 3.107 0.535 - 685.7 1 2 0 -0.0026 18 0 0 0 5.84E+07 3.13E+07 - - - 5.7788 0.9998 221125_WJC_METTL3_EV_vs_WT_F03.23962.23962.2 1.13E-09 14/32 R.FSGLPSNDEPILSFSPK.T sp|O00443|P3C2A_HUMAN 1 1833.9149 2.78 38411 23962 2 1833.911152 917.9647 Phosphatidylinositol 4-phosphate 3-kinase C2 domain-containing subunit alpha OS=Homo sapiens OX=9606 GN=PIK3C2A PE=1 SV=2 4.37 3720.6 - 1.33E+06 - - - -2.0328 - 2.53 0.583 - 456.8 1 2 0 -0.0037 17 0 0 0 2.29E+07 8.25E+06 - - - 5.6279 0.8786 221125_WJC_METTL3_EV_vs_WT_F03.23963.23963.2 0.546 Jun-38 K.LTGMERDLVAIEAKLSDLQK.E "sp|Q01082|SPTB2_HUMAN,tr|A0A087WUZ3|A0A087WUZ3_HUMAN" 2 2229.2039 999 38412 23963 2 2229.200717 1115.6092 "Spectrin beta chain, non-erythrocytic 1 OS=Homo sapiens OX=9606 GN=SPTBN1 PE=1 SV=2" 4.78 3720.8 - 1.29E+06 - - - -1.414 - 1.262 0.172 - 20.1 2 2 2 -0.0032 20 0 0 0 2.13E+07 0.00E+00 - - - 0.748 1 221125_WJC_METTL3_EV_vs_WT_F03.23964.23964.2 4.20E-06 13/30 K.MSADNQLQVIFITNDR.R "sp|Q9Y2L1|RRP44_HUMAN,tr|F2Z2C0|F2Z2C0_HUMAN,tr|G3V1J5|G3V1J5_HUMAN" 3 1863.9149 29.2 38413 23964 2 1863.909164 932.9647 Exosome complex exonuclease RRP44 OS=Homo sapiens OX=9606 GN=DIS3 PE=1 SV=2 4.21 3720.9 - 603649 - - - -3.0758 - 2.678 0.601 - 252.9 1 2 0 -0.0057 16 0 0 0 8.68E+06 2.97E+05 - - - 5.9 1 221125_WJC_METTL3_EV_vs_WT_F03.23967.23967.3 1.74E-07 21/68 R.VFEVSLADLQNDEVAFR[166.11]K[136.11].F "sp|P61247|RS3A_HUMAN,tr|H0Y8L7|H0Y8L7_HUMAN,tr|D6RI02|D6RI02_HUMAN,tr|D6RED7|D6RED7_HUMAN,tr|D6RGE0|D6RGE0_HUMAN,tr|D6RAS7|D6RAS7_HUMAN,tr|D6RB09|D6RB09_HUMAN,tr|E9PFI5|E9PFI5_HUMAN,tr|D6RAT0|D6RAT0_HUMAN,tr|D6RG13|D6RG13_HUMAN" 10 2097.0861 0.66 38414 23967 3 2097.08668 700.036 40S ribosomal protein S3a OS=Homo sapiens OX=9606 GN=RPS3A PE=1 SV=2 4.32 3721.3 - 9.68E+06 - - - 0.2575 - 4.161 0.603 - 468.2 1 2 0 0.0005 18 0 0 0 1.12E+08 1.69E+08 - - - 8.813 0.9932 221125_WJC_METTL3_EV_vs_WT_F03.23968.23968.2 6.39E-09 15/26 K.AFVDFLSDEIK[136.11]EER[166.11].K sp|Q07021|C1QBP_HUMAN 1 1714.8533 1.01 38415 23968 2 1714.857991 858.4339 "Complement component 1 Q subcomponent-binding protein, mitochondrial OS=Homo sapiens OX=9606 GN=C1QBP PE=1 SV=1" 4.18 3721.4 - 4.87E+06 - - - 2.7437 - 3.138 0.339 - 829.3 1 2 1 0.0047 14 0 0 0 6.98E+07 6.93E+07 - - - 4.4131 1 221125_WJC_METTL3_EV_vs_WT_F03.23971.23971.3 3.23E-10 20/68 H.IFASFNDTFVHVTDLSGK.E "sp|P62263|RS14_HUMAN,tr|A0A2R8Y811|A0A2R8Y811_HUMAN,tr|E5RH77|E5RH77_HUMAN" 3 1996.9894 0.78 38418 23971 3 1996.994474 666.6704 40S ribosomal protein S14 OS=Homo sapiens OX=9606 GN=RPS14 PE=1 SV=3 5.21 3721.5 - 3.18E+06 - - - 2.5198 - 3.646 0.669 - 379 1 1 0 0.005 18 0 0 0 2.29E+07 2.91E+07 - - - 9.2186 1 221125_WJC_METTL3_EV_vs_WT_F03.23972.23972.3 1.70E-06 17/76 K.DALNLAQMQEQTLQLEQQSK.L "sp|Q5T2N8|ATD3C_HUMAN,sp|Q9NVI7|ATD3A_HUMAN,tr|J3QSF3|J3QSF3_HUMAN,tr|H0Y2W2|H0Y2W2_HUMAN" 4 2315.1427 2.59 38419 23972 3 2315.137148 772.7215 ATPase family AAA domain-containing protein 3C OS=Homo sapiens OX=9606 GN=ATAD3C PE=2 SV=2 4.14 3721.7 - 2.53E+06 - - - -2.4089 - 3.455 0.492 - 469.6 1 2 0 -0.0056 20 0 0 0 3.93E+07 1.51E+07 - - - 7.0316 1 221125_WJC_METTL3_EV_vs_WT_F03.23977.23977.2 6.54E-10 17/34 R.FDSNC[160.03]ITPGTEFMDNLAK.C sp|Q9H0D6|XRN2_HUMAN 1 2058.9027 1.64 38424 23977 2 2058.896978 1030.4586 5'-3' exoribonuclease 2 OS=Homo sapiens OX=9606 GN=XRN2 PE=1 SV=1 4.03 3722.2 - 934814 - - - -2.7685 - 3.512 0.712 - 652.5 1 2 0 -0.0057 18 0 0 0 3.44E+07 2.10E+07 - - - 7.3864 1 221125_WJC_METTL3_EV_vs_WT_F03.23983.23983.3 1.23E-08 22/72 R.GIDIHGVPYVINVTLPDEK[136.11].Q "sp|Q92499|DDX1_HUMAN,tr|A0A7I2V2M5|A0A7I2V2M5_HUMAN,tr|A0A087X2G1|A0A087X2G1_HUMAN,tr|A0A7I2V430|A0A7I2V430_HUMAN,tr|A0A7I2V4F0|A0A7I2V4F0_HUMAN,tr|A0A087WZ71|A0A087WZ71_HUMAN" 6 2086.119 1.35 38428 23983 3 2086.122808 696.3803 ATP-dependent RNA helicase DDX1 OS=Homo sapiens OX=9606 GN=DDX1 PE=1 SV=2 4.54 3722.8 - 2.93E+06 - - - 1.822 - 3.913 0.578 - 547.6 1 2 0 0.0038 19 0 0 0 1.57E+08 1.16E+08 - - - 8.3349 1 221125_WJC_METTL3_EV_vs_WT_F03.23984.23984.3 3.42E-08 16/52 R.DFNHINVELSLLGK[136.11].K "sp|P32969|RL9_HUMAN,tr|D6RAN4|D6RAN4_HUMAN,tr|A0A2R8Y5Y7|A0A2R8Y5Y7_HUMAN" 3 1605.8606 0.97 38429 23984 3 1605.858924 536.2941 60S ribosomal protein L9 OS=Homo sapiens OX=9606 GN=RPL9 PE=1 SV=1 5.32 3722.9 - 2.56E+06 - - - -1.048 - 3.134 0.459 - 485.5 1 2 0 -0.0017 14 0 0 0 3.34E+07 3.43E+07 - - - 6.6927 1 221125_WJC_METTL3_EV_vs_WT_F03.23987.23987.2 2.72E-10 17/34 R.FDSNC[160.03]ITPGTEFMDNLAK[136.11].C sp|Q9H0D6|XRN2_HUMAN 1 2066.9169 1.64 38432 23987 2 2066.91369 1034.4657 5'-3' exoribonuclease 2 OS=Homo sapiens OX=9606 GN=XRN2 PE=1 SV=1 4.03 3723.2 - 1.87E+06 - - - -1.5424 - 3.653 0.699 - 652.9 1 2 0 -0.0032 18 0 0 0 3.44E+07 2.10E+07 - - - 7.388 1 221125_WJC_METTL3_EV_vs_WT_F03.23988.23988.3 2.66E-06 20/68 R.FDSNC[160.03]ITPGTEFMDNLAK[136.11].C sp|Q9H0D6|XRN2_HUMAN 1 2066.9169 0.82 38433 23988 3 2066.914478 689.9796 5'-3' exoribonuclease 2 OS=Homo sapiens OX=9606 GN=XRN2 PE=1 SV=1 4.03 3723.3 - 1.80E+06 - - - -1.1611 - 3.477 0.48 - 570.6 1 2 0 -0.0024 18 0 0 0 2.61E+07 3.17E+07 - - - 6.994 1 221125_WJC_METTL3_EV_vs_WT_F03.23993.23993.3 5.08E-06 18/88 R.TATESFASDPILYR[166.11]PVAVALDTK[136.11].G "sp|P14618|KPYM_HUMAN,tr|H3BQ34|H3BQ34_HUMAN,tr|H3BTJ2|H3BTJ2_HUMAN,tr|A0A804F6T5|A0A804F6T5_HUMAN,tr|H3BT25|H3BT25_HUMAN,tr|H3BUW1|H3BUW1_HUMAN,tr|H3BTN5|H3BTN5_HUMAN,tr|A0A804F729|A0A804F729_HUMAN" 8 2482.3074 1.51 38436 23993 3 2482.302895 828.4431 Pyruvate kinase PKM OS=Homo sapiens OX=9606 GN=PKM PE=1 SV=4 4.56 3723.8 - 4.51E+06 - - - -1.8253 - 3.586 0.597 - 294.7 1 2 0 -0.0045 23 0 0 0 2.01E+08 1.33E+08 - - - 8.1906 0.9999 221125_WJC_METTL3_EV_vs_WT_F03.23994.23994.3 5.21E-06 Nov-52 R.DFNHINVELSLLGK.K "sp|P32969|RL9_HUMAN,tr|D6RAN4|D6RAN4_HUMAN,tr|A0A2R8Y5Y7|A0A2R8Y5Y7_HUMAN" 3 1597.8464 0.97 38437 23994 3 1597.843099 533.6227 60S ribosomal protein L9 OS=Homo sapiens OX=9606 GN=RPL9 PE=1 SV=1 5.32 3723.9 - 2.90E+06 - - - -2.0703 - 2.277 0.459 - 169.8 1 2 0 -0.0033 14 0 0 0 3.34E+07 3.43E+07 - - - 5.8433 1 221125_WJC_METTL3_EV_vs_WT_F03.23997.23997.2 1.04E-06 17/34 K.EAPETDTSPSLWDVEFAK[136.11].Q sp|Q92665|RT31_HUMAN 1 2028.9408 1.86 38440 23997 2 2028.937484 1015.4777 "28S ribosomal protein S31, mitochondrial OS=Homo sapiens OX=9606 GN=MRPS31 PE=1 SV=3" 3.83 3724.3 - 1.64E+06 - - - -1.6181 - 3.086 0.625 - 774 1 2 0 -0.0033 18 0 0 0 5.80E+07 3.11E+07 - - - 6.4267 1 221125_WJC_METTL3_EV_vs_WT_F03.23998.23998.3 4.57E-08 19/60 R.VVSVLTVVHQDWLNGK.E "sp|P01859|IGHG2_HUMAN,tr|A0A286YEY4|A0A286YEY4_HUMAN" 2 1792.9836 12.16 38441 23998 3 1792.98567 598.6685 Immunoglobulin heavy constant gamma 2 OS=Homo sapiens OX=9606 GN=IGHG2 PE=1 SV=2 6.71 3724.4 - 1.50E+06 - - - 1.1718 - 3.835 0.543 - 341.5 1 2 0 0.0021 16 0 0 0 1.12E+07 9.18E+05 - - - 8.0423 0.9999 221125_WJC_METTL3_EV_vs_WT_F03.23999.23999.3 2.93E-05 18/76 R.LPIPRPGEVLGLVGTNGIGK.S "sp|P61221|ABCE1_HUMAN,tr|H0Y990|H0Y990_HUMAN,tr|D6RGF4|D6RGF4_HUMAN,tr|D6R9I9|D6R9I9_HUMAN" 4 1986.1626 1.01 38442 23999 3 1986.156769 663.0615 ATP-binding cassette sub-family E member 1 OS=Homo sapiens OX=9606 GN=ABCE1 PE=1 SV=1 8.75 3724.5 - 806509 - - - -2.9338 - 3.098 0.481 - 327.5 1 2 0 -0.0058 20 0 0 0 1.09E+07 1.08E+07 - - - 6.6443 0.9992 221125_WJC_METTL3_EV_vs_WT_F03.24000.24000.3 9.81E-08 15/56 K.GEQLFLEPELVIPHR.Q "sp|Q9NXE4|NSMA3_HUMAN,tr|H7C0W5|H7C0W5_HUMAN,tr|H7C2J2|H7C2J2_HUMAN,tr|H7C1Q6|H7C1Q6_HUMAN,tr|H7C235|H7C235_HUMAN,tr|A0A7P0TB44|A0A7P0TB44_HUMAN,tr|A0A7P0T9J6|A0A7P0T9J6_HUMAN,tr|A0A7P0TB24|A0A7P0TB24_HUMAN" 8 1775.957 2.63 38443 24000 3 1776.957804 592.9929 Sphingomyelin phosphodiesterase 4 OS=Homo sapiens OX=9606 GN=SMPD4 PE=1 SV=3 4.75 3724.6 - 730159 - - - 563.5181 - 3.078 0.521 - 322.5 1 2 0 1.0008 15 0 0 0 1.62E+07 6.14E+06 - - - 7.0051 1 221125_WJC_METTL3_EV_vs_WT_F03.24003.24003.3 1.12E-10 22/88 R.TATESFASDPILYRPVAVALDTK.G "sp|P14618|KPYM_HUMAN,tr|H3BQ34|H3BQ34_HUMAN,tr|H3BTJ2|H3BTJ2_HUMAN,tr|A0A804F6T5|A0A804F6T5_HUMAN,tr|H3BT25|H3BT25_HUMAN,tr|H3BUW1|H3BUW1_HUMAN,tr|H3BTN5|H3BTN5_HUMAN,tr|A0A804F729|A0A804F729_HUMAN" 8 2464.285 1.6 38444 24003 3 2464.281172 822.4356 Pyruvate kinase PKM OS=Homo sapiens OX=9606 GN=PKM PE=1 SV=4 4.56 3725 - 9.85E+06 - - - -1.5355 - 3.612 0.658 - 438.3 1 2 0 -0.0038 23 0 0 0 2.14E+08 1.34E+08 - - - 8.8878 0.9994 221125_WJC_METTL3_EV_vs_WT_F03.24007.24007.3 0.000379 14/56 K.GEQLFLEPELVIPHR[166.11].Q "sp|Q9NXE4|NSMA3_HUMAN,tr|H7C0W5|H7C0W5_HUMAN,tr|H7C2J2|H7C2J2_HUMAN,tr|H7C1Q6|H7C1Q6_HUMAN,tr|H7C235|H7C235_HUMAN,tr|A0A7P0TB44|A0A7P0TB44_HUMAN,tr|A0A7P0T9J6|A0A7P0T9J6_HUMAN,tr|A0A7P0TB24|A0A7P0TB24_HUMAN" 8 1785.9653 2.56 38448 24007 3 1785.970725 596.329 Sphingomyelin phosphodiesterase 4 OS=Homo sapiens OX=9606 GN=SMPD4 PE=1 SV=3 4.75 3725.5 - 954356 - - - 3.0432 - 2.573 0.341 - 243.4 1 2 0 0.0054 15 0 0 0 1.57E+07 6.14E+06 - - - 4.8063 0.9939 221125_WJC_METTL3_EV_vs_WT_F03.24009.24009.2 9.54E-08 14/32 R.SVTTVQWENSFVSVYSK[136.11].D sp|Q6P2Q9|PRP8_HUMAN 1 1967.972 2.21 38450 24009 2 1968.972548 984.9933 Pre-mRNA-processing-splicing factor 8 OS=Homo sapiens OX=9606 GN=PRPF8 PE=1 SV=2 5.72 3725.7 - 629805 - - - 508.4117 - 2.58 0.563 - 475.6 1 2 0 1.0005 17 0 0 0 4.86E+06 2.20E+06 - - - 5.2153 0.9997 221125_WJC_METTL3_EV_vs_WT_F03.24014.24014.3 1.11E-06 20/80 R.NPPGFAFVEFEDPR[166.11]DAADAVR[166.11].E "sp|P84103|SRSF3_HUMAN,tr|A0A087X2D0|A0A087X2D0_HUMAN" 2 2339.1085 1.52 38453 24014 3 2339.10456 780.7101 Serine\arginine-rich splicing factor 3 OS=Homo sapiens OX=9606 GN=SRSF3 PE=1 SV=1 4.11 3726.3 - 7.30E+06 - - - -1.7058 - 2.698 0.469 - 233.6 1 2 1 -0.004 21 0 0 0 2.47E+08 1.63E+08 - - - 6.1473 1 221125_WJC_METTL3_EV_vs_WT_F03.24015.24015.3 2.72E-13 22/72 R.GIDIHGVPYVINVTLPDEK.Q "sp|Q92499|DDX1_HUMAN,tr|A0A7I2V2M5|A0A7I2V2M5_HUMAN,tr|A0A087X2G1|A0A087X2G1_HUMAN,tr|A0A7I2V430|A0A7I2V430_HUMAN,tr|A0A7I2V4F0|A0A7I2V4F0_HUMAN,tr|A0A087WZ71|A0A087WZ71_HUMAN" 6 2078.1048 1.35 38454 24015 3 2078.110848 693.7089 ATP-dependent RNA helicase DDX1 OS=Homo sapiens OX=9606 GN=DDX1 PE=1 SV=2 4.54 3726.3 - 1.62E+07 - - - 2.907 - 3.596 0.628 - 521.1 1 2 0 0.006 19 0 0 0 1.57E+08 1.16E+08 - - - 8.6842 1 221125_WJC_METTL3_EV_vs_WT_F03.24019.24019.3 2.52E-11 18/68 P.DHPAVAATLNNLAVLYGK.R "sp|Q9NSK0|KLC4_HUMAN,sp|Q9H0B6|KLC2_HUMAN,sp|Q07866|KLC1_HUMAN,tr|G3V5R9|G3V5R9_HUMAN,tr|G3V3H3|G3V3H3_HUMAN,tr|F8W6L3|F8W6L3_HUMAN,tr|A8MZ87|A8MZ87_HUMAN,tr|E7EVH7|E7EVH7_HUMAN,tr|G3V2E7|G3V2E7_HUMAN,tr|G5E9S8|G5E9S8_HUMAN" 10 1865.9999 2.78 38458 24019 3 1866.000305 623.0073 Kinesin light chain 4 OS=Homo sapiens OX=9606 GN=KLC4 PE=1 SV=3 6.74 3726.7 - 1.38E+06 - - - 0.1919 - 3.421 0.629 - 489.6 1 1 0 0.0004 18 0 0 0 2.26E+07 8.13E+06 - - - 8.6153 0.9685 221125_WJC_METTL3_EV_vs_WT_F03.24020.24020.3 0.00191 14/56 K.NEQAFEEVFQNANFR.S "sp|P27694|RFA1_HUMAN,tr|I3L4R8|I3L4R8_HUMAN" 2 1841.8333 1.53 38459 24020 3 1842.828475 614.9517 Replication protein A 70 kDa DNA-binding subunit OS=Homo sapiens OX=9606 GN=RPA1 PE=1 SV=2 4.25 3726.8 - 953131 - - - 540.3307 - 2.69 0.385 - 269.4 1 2 0 0.9952 15 0 0 0 9.98E+06 6.54E+06 - - - 5.1388 0.9992 221125_WJC_METTL3_EV_vs_WT_F03.24021.24021.3 0.000225 Nov-48 R.LDIISEDISELQK.N sp|Q7Z3B4|NUP54_HUMAN 1 1501.7876 3.12 38460 24021 3 1501.784694 501.6031 Nucleoporin p54 OS=Homo sapiens OX=9606 GN=NUP54 PE=1 SV=2 3.92 3726.9 - 391813 - - - -1.9051 - 2.023 0.306 - 187.1 1 2 0 -0.0029 13 0 0 0 3.50E+06 1.12E+06 - - - 3.8611 1 221125_WJC_METTL3_EV_vs_WT_F03.24026.24026.3 2.78E-10 22/88 K.FLAAGTHLGGTNLDFQMEQYIYK[136.11].R "sp|P08865|RSSA_HUMAN,tr|C9J9K3|C9J9K3_HUMAN,tr|A0A0C4DG17|A0A0C4DG17_HUMAN,tr|F8WD59|F8WD59_HUMAN" 4 2624.2825 0.54 38463 24026 3 2624.28136 875.7681 40S ribosomal protein SA OS=Homo sapiens OX=9606 GN=RPSA PE=1 SV=4 5.32 3727.5 - 2.75E+06 - - - -0.4192 - 4.122 0.622 - 321.4 1 2 0 -0.0011 23 0 0 0 7.12E+06 1.31E+07 - - - 8.797 1 221125_WJC_METTL3_EV_vs_WT_F03.24030.24030.3 1.66E-08 21/64 K.NGGLGHMNIALLSDLTK[136.11].Q sp|P30048|PRDX3_HUMAN 1 1760.9335 1.06 38467 24030 3 1760.933306 587.9851 "Thioredoxin-dependent peroxide reductase, mitochondrial OS=Homo sapiens OX=9606 GN=PRDX3 PE=1 SV=3" 6.74 3727.9 - 1.11E+06 - - - -0.084 - 3.879 0.553 - 676 1 2 0 -0.0001 17 0 0 0 1.23E+07 1.16E+07 - - - 8.13 0.9998 221125_WJC_METTL3_EV_vs_WT_F03.24034.24034.3 7.41E-05 14/60 K.YGIVDYMIEQSGPPSK[136.11].E "sp|P13667|PDIA4_HUMAN,tr|A0A499FI48|A0A499FI48_HUMAN" 2 1790.864 1.28 38471 24034 3 1790.868786 597.962 Protein disulfide-isomerase A4 OS=Homo sapiens OX=9606 GN=PDIA4 PE=1 SV=2 4.37 3728.5 - 761272 - - - 2.6518 - 2.695 0.418 - 193.4 1 2 0 0.0047 16 0 0 0 8.01E+06 6.25E+06 - - - 5.7428 0.9989 221125_WJC_METTL3_EV_vs_WT_F03.24035.24035.3 1.90E-05 15/44 R.FKEANNFLWPFK.L "sp|P18124|RL7_HUMAN,tr|A8MUD9|A8MUD9_HUMAN" 2 1539.7874 0.59 38472 24035 3 1539.791006 514.2698 60S ribosomal protein L7 OS=Homo sapiens OX=9606 GN=RPL7 PE=1 SV=1 8.59 3728.6 - 617285 - - - 2.3192 - 2.109 0.415 - 207 1 2 1 0.0036 12 0 0 0 4.21E+07 7.16E+07 - - - 5.2342 1 221125_WJC_METTL3_EV_vs_WT_F03.24038.24038.3 3.04E-06 13/56 R.NENQLIIFADDTYPR.W sp|Q15393|SF3B3_HUMAN 1 1807.8741 0.31 38475 24038 3 1807.874771 603.632 Splicing factor 3B subunit 3 OS=Homo sapiens OX=9606 GN=SF3B3 PE=1 SV=4 4.03 3729 - 391034 - - - 0.3833 - 2.572 0.493 - 203.6 1 2 0 0.0007 15 0 0 0 4.87E+06 1.55E+07 - - - 6.5013 1 221125_WJC_METTL3_EV_vs_WT_F03.24041.24041.3 6.64E-11 25/96 K.IVSLFAEHNDLQYAAPGGLIGVGTK.L "sp|Q2VIR3|IF2GL_HUMAN,sp|P41091|IF2G_HUMAN" 2 2569.354 0.75 38476 24041 3 2569.353922 857.4586 Eukaryotic translation initiation factor 2 subunit 3B OS=Homo sapiens OX=9606 GN=EIF2S3B PE=2 SV=2 5.32 3729.4 - 7.15E+06 - - - -0.0451 - 4.528 0.633 - 550.5 1 2 0 -0.0001 25 0 0 0 4.57E+07 6.11E+07 - - - 9.0719 1 221125_WJC_METTL3_EV_vs_WT_F03.24042.24042.3 6.97E-11 26/72 R.LSNTQGVVSAFSTMMSVHR.G "sp|P48047|ATPO_HUMAN,tr|H7C0C1|H7C0C1_HUMAN,tr|H7C068|H7C068_HUMAN,tr|A0A494C0K9|A0A494C0K9_HUMAN" 4 2050.9928 0.18 38477 24042 3 2050.992177 684.6716 "ATP synthase subunit O, mitochondrial OS=Homo sapiens OX=9606 GN=ATP5PO PE=1 SV=1" 9.76 3729.4 - 5.78E+06 - - - -0.3184 - 4.259 0.657 - 1173.1 1 2 0 -0.0007 19 0 0 0 5.91E+07 3.21E+08 - - - 9.4247 1 221125_WJC_METTL3_EV_vs_WT_F03.24043.24043.3 3.97E-10 25/96 K.IVSLFAEHNDLQYAAPGGLIGVGTK[136.11].L "sp|Q2VIR3|IF2GL_HUMAN,sp|P41091|IF2G_HUMAN" 2 2577.3682 0.75 38478 24043 3 2577.367921 860.13 Eukaryotic translation initiation factor 2 subunit 3B OS=Homo sapiens OX=9606 GN=EIF2S3B PE=2 SV=2 5.32 3729.5 - 8.16E+06 - - - -0.123 - 4.57 0.707 - 548.5 1 2 0 -0.0003 25 0 0 0 4.57E+07 6.11E+07 - - - 9.9181 1 221125_WJC_METTL3_EV_vs_WT_F03.24044.24044.3 7.67E-05 22/72 R.LSNTQGVVSAFSTMMSVHR[166.11].G "sp|P48047|ATPO_HUMAN,tr|H7C0C1|H7C0C1_HUMAN,tr|H7C068|H7C068_HUMAN,tr|A0A494C0K9|A0A494C0K9_HUMAN" 4 2061.0011 0.88 38479 24044 3 2061.002511 688.0076 "ATP synthase subunit O, mitochondrial OS=Homo sapiens OX=9606 GN=ATP5PO PE=1 SV=1" 9.76 3729.5 - 6.46E+06 - - - 0.6846 - 4.185 0.567 - 838.1 1 2 0 0.0014 19 0 0 0 4.83E+07 5.52E+07 - - - 8.378 1 221125_WJC_METTL3_EV_vs_WT_F03.24045.24045.3 5.07E-17 31/116 K.WLNDAENLSSDSSLSSPSALNSPGIEGLSR.R "sp|P14859|PO2F1_HUMAN,tr|A0A0C4DG88|A0A0C4DG88_HUMAN,tr|A0A0A0MT46|A0A0A0MT46_HUMAN" 3 3102.4742 2.55 38480 24045 3 3102.476055 1035.1653 "POU domain, class 2, transcription factor 1 OS=Homo sapiens OX=9606 GN=POU2F1 PE=1 SV=2" 3.92 3729.6 - 4.37E+06 - - - 0.6089 - 4.808 0.662 - 801.9 1 2 0 0.0019 30 0 0 0 3.65E+07 1.43E+07 - - - 9.5328 0.9999 221125_WJC_METTL3_EV_vs_WT_F03.24046.24046.3 1.66E-07 16/68 K.LQVDYTGLIQSYEQNETK.L "sp|Q15643|TRIPB_HUMAN,tr|H0YJ97|H0YJ97_HUMAN" 2 2128.0324 1.01 38481 24046 3 2128.026418 710.3514 Thyroid receptor-interacting protein 11 OS=Homo sapiens OX=9606 GN=TRIP11 PE=1 SV=3 4.14 3729.7 - 3.37E+06 - - - -2.8247 - 2.995 0.504 - 340 1 2 0 -0.006 18 0 0 0 2.00E+07 1.98E+07 - - - 6.8889 0.9999 221125_WJC_METTL3_EV_vs_WT_F03.24048.24048.3 1.22E-05 15/64 R.EATVKPFAIDIFPVTNK.D "sp|Q8NBJ7|SUMF2_HUMAN,tr|A8MXB9|A8MXB9_HUMAN,tr|F8WEX5|F8WEX5_HUMAN,tr|F8WA42|F8WA42_HUMAN,tr|H7C3B2|H7C3B2_HUMAN,tr|E9PBT8|E9PBT8_HUMAN,tr|J3KQJ1|J3KQJ1_HUMAN,tr|E9PG02|E9PG02_HUMAN,tr|C9JL30|C9JL30_HUMAN,tr|J3QT17|J3QT17_HUMAN,tr|A0A494C1B1|A0A494C1B1_HUMAN,tr|F8WES7|F8WES7_HUMAN,tr|F8WEV7|F8WEV7_HUMAN,tr|C9J660|C9J660_HUMAN" 14 1889.0299 2.26 38483 24048 3 1889.033548 630.6839 Inactive C-alpha-formylglycine-generating enzyme 2 OS=Homo sapiens OX=9606 GN=SUMF2 PE=1 SV=2 6.17 3729.9 - 1.42E+06 - - - 1.9571 - 3.022 0.415 - 143.7 1 2 0 0.0037 17 0 0 0 1.08E+07 4.76E+06 - - - 5.9597 1 221125_WJC_METTL3_EV_vs_WT_F03.24050.24050.3 5.91E-08 17/72 K.FIAHVPVPSQQEIEEALVR.R sp|Q9ULR0|ISY1_HUMAN 1 2161.1532 2.35 38485 24050 3 2161.151723 721.3917 Pre-mRNA-splicing factor ISY1 homolog OS=Homo sapiens OX=9606 GN=ISY1 PE=1 SV=3 4.75 3730.2 - 1.07E+06 - - - -0.6621 - 3.201 0.446 - 358.6 1 2 0 -0.0014 19 0 0 0 2.29E+07 9.72E+06 - - - 6.3705 1 221125_WJC_METTL3_EV_vs_WT_F03.24051.24051.2 3.11E-11 16/32 R.DSEEPFSSVEIQAALSK.M "sp|P25205|MCM3_HUMAN,tr|J3KQ69|J3KQ69_HUMAN,tr|A0A499FHX9|A0A499FHX9_HUMAN" 3 1835.8789 0.06 38486 24051 2 1835.892548 918.9467 DNA replication licensing factor MCM3 OS=Homo sapiens OX=9606 GN=MCM3 PE=1 SV=3 4 3730.3 - 1.03E+06 - - - 7.44 - 3.401 0.636 - 765.5 1 2 0 0.0137 17 0 0 0 9.41E+06 1.50E+08 - - - 6.7436 1 221125_WJC_METTL3_EV_vs_WT_F03.24052.24052.3 3.33E-05 18/56 K.VNPAAALEELEKIEK.A "sp|Q9BVJ6|UT14A_HUMAN,tr|X6RJY0|X6RJY0_HUMAN" 2 1652.8985 1.5 38487 24052 3 1652.898956 551.9734 U3 small nucleolar RNA-associated protein 14 homolog A OS=Homo sapiens OX=9606 GN=UTP14A PE=1 SV=1 4.49 3730.4 - 964002 - - - 0.2747 - 3.974 0.571 - 468.2 1 2 1 0.0005 15 0 0 0 1.37E+07 9.11E+06 - - - 8.5063 0.998 221125_WJC_METTL3_EV_vs_WT_F03.24054.24054.3 2.92E-07 15/68 P.DHPAVAATLNNLAVLYGK[136.11].R "sp|Q9NSK0|KLC4_HUMAN,sp|Q9H0B6|KLC2_HUMAN,sp|Q07866|KLC1_HUMAN,tr|G3V5R9|G3V5R9_HUMAN,tr|G3V3H3|G3V3H3_HUMAN,tr|F8W6L3|F8W6L3_HUMAN,tr|A8MZ87|A8MZ87_HUMAN,tr|E7EVH7|E7EVH7_HUMAN,tr|G3V2E7|G3V2E7_HUMAN,tr|G5E9S8|G5E9S8_HUMAN" 10 1874.0141 2.2 38489 24054 3 1874.01504 625.6787 Kinesin light chain 4 OS=Homo sapiens OX=9606 GN=KLC4 PE=1 SV=3 6.74 3730.7 - 863076 - - - 0.4765 - 2.883 0.534 - 360.5 1 1 0 0.0009 18 0 0 0 1.79E+07 8.13E+06 - - - 7.1299 0.9997 221125_WJC_METTL3_EV_vs_WT_F03.24056.24056.3 5.05E-07 18/60 R.MGAGSSIIENLQSQLK[136.11].L "sp|P82094|TMF1_HUMAN,tr|A0A2R8Y7M0|A0A2R8Y7M0_HUMAN" 2 1682.8753 1.59 38491 24056 3 1682.882805 561.9657 TATA element modulatory factor OS=Homo sapiens OX=9606 GN=TMF1 PE=1 SV=2 5.75 3730.9 - 530368 - - - 4.4769 - 3.138 0.481 - 423 1 2 0 0.0075 16 0 0 0 2.03E+07 1.28E+07 - - - 6.8349 1 221125_WJC_METTL3_EV_vs_WT_F03.24062.24062.3 5.12E-14 21/56 K.ILFIFIDSDHTDNQR[166.11].L "sp|P07237|PDIA1_HUMAN,tr|A0A7P0TA97|A0A7P0TA97_HUMAN,tr|A0A7P0T8C0|A0A7P0T8C0_HUMAN,tr|H7BZ94|H7BZ94_HUMAN,tr|A0A7P0TA71|A0A7P0TA71_HUMAN,tr|I3L4M2|I3L4M2_HUMAN,tr|A0A7P0T9D6|A0A7P0T9D6_HUMAN,tr|A0A7P0T9K9|A0A7P0T9K9_HUMAN,tr|H0Y3Z3|H0Y3Z3_HUMAN,tr|A0A7P0TA35|A0A7P0TA35_HUMAN,tr|I3L514|I3L514_HUMAN,tr|A0A7P0TB26|A0A7P0TB26_HUMAN,tr|A0A7P0T9U6|A0A7P0T9U6_HUMAN,tr|I3L0S0|I3L0S0_HUMAN,tr|I3L3P5|I3L3P5_HUMAN,tr|A0A7P0T8J3|A0A7P0T8J3_HUMAN,tr|A0A7P0T8X1|A0A7P0T8X1_HUMAN" 17 1842.914 2.3 38495 24062 3 1842.913923 615.3119 Protein disulfide-isomerase OS=Homo sapiens OX=9606 GN=P4HB PE=1 SV=3 4.41 3731.6 - 2.26E+06 - - - -0.0326 - 3.68 0.687 - 594.7 1 2 0 -0.0001 15 0 0 0 1.26E+08 5.47E+07 - - - 9.5991 1 221125_WJC_METTL3_EV_vs_WT_F03.24064.24064.3 1.67E-07 16/68 K.LDAENAIVHMGGQWLGGR.Q "sp|Q01085|TIAR_HUMAN,tr|E7ETJ9|E7ETJ9_HUMAN" 2 1922.9421 7.66 38497 24064 3 1922.943232 641.988 Nucleolysin TIAR OS=Homo sapiens OX=9606 GN=TIAL1 PE=1 SV=1 5.32 3731.7 - 2.03E+06 - - - 0.5809 - 3.447 0.564 - 340.2 1 2 0 0.0011 18 0 0 0 3.70E+07 4.83E+06 - - - 7.9092 1 221125_WJC_METTL3_EV_vs_WT_F03.24066.24066.3 3.43E-08 14/60 R.MGAGSSIIENLQSQLK.L "sp|P82094|TMF1_HUMAN,tr|A0A2R8Y7M0|A0A2R8Y7M0_HUMAN" 2 1674.8611 1.64 38499 24066 3 1674.862354 559.2943 TATA element modulatory factor OS=Homo sapiens OX=9606 GN=TMF1 PE=1 SV=2 5.75 3731.9 - 1.77E+06 - - - 0.766 - 2.764 0.551 - 347.4 1 2 0 0.0013 16 0 0 0 2.09E+07 1.28E+07 - - - 7.2914 1 221125_WJC_METTL3_EV_vs_WT_F03.24069.24069.3 3.56E-08 16/56 K.HSQFLGYPITLYLEK[136.11].E "sp|Q58FF8|H90B2_HUMAN,sp|P08238|HS90B_HUMAN,sp|Q58FF7|H90B3_HUMAN" 3 1815.9651 0.82 38502 24069 3 1815.966782 606.329 Putative heat shock protein HSP 90-beta 2 OS=Homo sapiens OX=9606 GN=HSP90AB2P PE=1 SV=2 6.75 3732.1 - 1.06E+06 - - - 0.9416 - 3.032 0.524 - 282.6 1 2 0 0.0017 15 0 0 0 1.11E+08 1.36E+08 - - - 7.276 1 221125_WJC_METTL3_EV_vs_WT_F03.24070.24070.3 3.24E-09 20/72 K.QLLQNPPAGVDPIIWEQAK.V sp|Q7Z3B4|NUP54_HUMAN 1 2116.1317 1.22 38503 24070 3 2116.135934 706.3845 Nucleoporin p54 OS=Homo sapiens OX=9606 GN=NUP54 PE=1 SV=2 4.37 3732.2 - 896962 - - - 2.0055 - 3.469 0.523 - 560.5 1 2 0 0.0042 19 0 0 0 2.90E+07 2.37E+07 - - - 7.4257 1 221125_WJC_METTL3_EV_vs_WT_F03.24071.24071.3 3.84E-08 20/56 K.HSQFLGYPITLYLEK.E "sp|Q58FF8|H90B2_HUMAN,sp|P08238|HS90B_HUMAN,sp|Q58FF7|H90B3_HUMAN" 3 1807.9509 0.82 38504 24071 3 1807.952232 603.6576 Putative heat shock protein HSP 90-beta 2 OS=Homo sapiens OX=9606 GN=HSP90AB2P PE=1 SV=2 6.75 3732.4 - 879411 - - - 0.7522 - 3.188 0.57 - 401.4 1 2 0 0.0014 15 0 0 0 1.11E+08 1.35E+08 - - - 7.9198 0.9999 221125_WJC_METTL3_EV_vs_WT_F03.24072.24072.2 8.13E-06 26-Nov K.SESVPPVTDWAWYK.L "sp|P35613|BASI_HUMAN,tr|A0A7P0T8A7|A0A7P0T8A7_HUMAN,tr|A0A087WUV8|A0A087WUV8_HUMAN,tr|A0A7P0TA85|A0A7P0TA85_HUMAN,tr|A0A7P0TB04|A0A7P0TB04_HUMAN,tr|R4GMX5|R4GMX5_HUMAN,tr|R4GN83|R4GN83_HUMAN,tr|I3L192|I3L192_HUMAN" 8 1663.7882 1.05 38505 24072 2 1663.787606 832.9014 Basigin OS=Homo sapiens OX=9606 GN=BSG PE=1 SV=2 4.37 3732.5 - 874097 - - - -0.3708 - 2.061 0.591 - 254.6 1 2 0 -0.0006 14 0 0 0 1.06E+07 1.00E+07 - - - 5.2207 0.9989 221125_WJC_METTL3_EV_vs_WT_F03.24074.24074.2 4.50E-07 Dec-36 K.DSGPLPTPPGVSLLGEPPK.D "tr|E9PAU2|E9PAU2_HUMAN,tr|A0A087WZ13|A0A087WZ13_HUMAN" 2 1856.9884 0.81 38507 24074 2 1856.995317 929.5015 Ribonucleoprotein PTB-binding 1 OS=Homo sapiens OX=9606 GN=RAVER1 PE=1 SV=1 4.37 3732.8 - 766254 - - - 3.7356 - 2.177 0.489 - 234.8 1 2 0 0.0069 19 0 0 0 1.91E+07 2.35E+07 - - - 4.5632 0.9999 221125_WJC_METTL3_EV_vs_WT_F03.24075.24075.3 0.000128 13/64 K.ALESPERPFLAILGGAK.V sp|P00558|PGK1_HUMAN 1 1767.9883 1.31 38508 24075 3 1767.99168 590.3367 Phosphoglycerate kinase 1 OS=Homo sapiens OX=9606 GN=PGK1 PE=1 SV=3 6.19 3732.9 - 654366 - - - 1.9005 - 2.567 0.453 - 157.9 1 2 0 0.0034 17 0 0 0 1.84E+07 1.41E+07 - - - 5.9712 0.9999 221125_WJC_METTL3_EV_vs_WT_F03.24078.24078.2 1.37E-07 15/36 K.DSGPLPTPPGVSLLGEPPK[136.11].D "tr|E9PAU2|E9PAU2_HUMAN,tr|A0A087WZ13|A0A087WZ13_HUMAN" 2 1865.0026 0.81 38511 24078 2 1865.001326 933.5086 Ribonucleoprotein PTB-binding 1 OS=Homo sapiens OX=9606 GN=RAVER1 PE=1 SV=1 4.37 3733.2 - 591411 - - - -0.6724 - 2.425 0.565 - 418.3 1 2 0 -0.0013 19 0 0 0 1.91E+07 2.35E+07 - - - 5.3916 1 221125_WJC_METTL3_EV_vs_WT_F03.24083.24083.2 1.43E-09 19/32 R.STGEAFVQFASQEIAEK.A "sp|P55795|HNRH2_HUMAN,sp|P31943|HNRH1_HUMAN,tr|E5RGH4|E5RGH4_HUMAN,tr|H0YB39|H0YB39_HUMAN,tr|E5RGV0|E5RGV0_HUMAN,tr|E9PCY7|E9PCY7_HUMAN,tr|D6RIU0|D6RIU0_HUMAN,tr|D6RBM0|D6RBM0_HUMAN,tr|G8JLB6|G8JLB6_HUMAN,tr|E7EN40|E7EN40_HUMAN" 10 1840.8843 1.25 38514 24083 2 1840.883927 921.4494 Heterogeneous nuclear ribonucleoprotein H2 OS=Homo sapiens OX=9606 GN=HNRNPH2 PE=1 SV=1 4.25 3733.9 - 1.04E+07 - - - -0.2075 - 3.632 0.671 - 1462.1 1 2 0 -0.0004 17 0 0 0 1.01E+09 8.11E+08 - - - 7.1679 1 221125_WJC_METTL3_EV_vs_WT_F03.24084.24084.2 4.46E-10 19/32 R.STGEAFVQFASQEIAEK[136.11].A "sp|P55795|HNRH2_HUMAN,sp|P31943|HNRH1_HUMAN,tr|E5RGH4|E5RGH4_HUMAN,tr|H0YB39|H0YB39_HUMAN,tr|E5RGV0|E5RGV0_HUMAN,tr|E9PCY7|E9PCY7_HUMAN,tr|D6RIU0|D6RIU0_HUMAN,tr|D6RBM0|D6RBM0_HUMAN,tr|G8JLB6|G8JLB6_HUMAN,tr|E7EN40|E7EN40_HUMAN" 10 1848.8985 1.24 38515 24084 2 1848.897161 925.4565 Heterogeneous nuclear ribonucleoprotein H2 OS=Homo sapiens OX=9606 GN=HNRNPH2 PE=1 SV=1 4.25 3733.9 - 1.07E+07 - - - -0.7291 - 3.678 0.648 - 1414.2 1 2 0 -0.0013 17 0 0 0 1.00E+09 8.10E+08 - - - 7.0286 1 221125_WJC_METTL3_EV_vs_WT_F03.24086.24086.3 4.77E-07 19/72 K.ILTATVDNANVLLQIDNAR.L sp|P02533|K1C14_HUMAN 1 2053.1168 657.66 38517 24086 3 2053.119423 685.3795 "Keratin, type I cytoskeletal 14 OS=Homo sapiens OX=9606 GN=KRT14 PE=1 SV=4" 4.21 3734.1 - 2.30E+06 - - - 1.2932 - 3.366 0.514 - 446.7 1 2 0 0.0027 19 0 0 0 1.12E+08 1.70E+05 - - - 7.2517 1 221125_WJC_METTL3_EV_vs_WT_F03.24091.24091.3 3.22E-10 21/104 K.ALVLDC[160.03]HYPEDEVGQEDEAESDIFSIR.E "sp|Q07021|C1QBP_HUMAN,tr|I3L3B0|I3L3B0_HUMAN,tr|I3L3Q7|I3L3Q7_HUMAN" 3 3135.3979 1.17 38522 24091 3 3135.398566 1046.1399 "Complement component 1 Q subcomponent-binding protein, mitochondrial OS=Homo sapiens OX=9606 GN=C1QBP PE=1 SV=1" 3.8 3734.6 - 967734 - - - 0.2156 - 4.105 0.751 - 514.3 1 2 0 0.0007 27 0 0 0 2.30E+07 1.97E+07 - - - 10.1617 0.999 221125_WJC_METTL3_EV_vs_WT_F03.24093.24093.3 0.00289 13/88 R.QLTSYVGSVR[166.11]PLVTELDPDAPIR[166.11].Q sp|P57740|NU107_HUMAN 1 2545.3655 2.33 38524 24093 3 2545.366383 849.4624 Nuclear pore complex protein Nup107 OS=Homo sapiens OX=9606 GN=NUP107 PE=1 SV=1 4.56 3734.9 - 1.35E+06 - - - 0.3497 - 1.987 0.286 - 96.7 1 2 0 0.0009 23 0 0 0 1.32E+07 5.68E+06 - - - 3.3392 1 221125_WJC_METTL3_EV_vs_WT_F03.24096.24096.2 1.05E-06 17/32 K.VTLENFYSNLIAQHEER.E sp|Q15208|STK38_HUMAN 1 2062.012 5.51 38527 24096 2 2062.017017 1032.0133 Serine\threonine-protein kinase 38 OS=Homo sapiens OX=9606 GN=STK38 PE=1 SV=1 4.75 3735.3 - 347562 - - - 2.4481 - 3.82 0.627 - 989 1 2 0 0.005 17 0 0 0 1.80E+07 3.27E+06 - - - 6.9655 1 221125_WJC_METTL3_EV_vs_WT_F03.24099.24099.3 5.05E-06 20/76 K.LQQELEFLEVQEEYIK[136.11]DEQK[136.11].N sp|P43686|PRS6B_HUMAN 1 2553.2821 1.02 38528 24099 3 2553.280579 852.1013 26S proteasome regulatory subunit 6B OS=Homo sapiens OX=9606 GN=PSMC4 PE=1 SV=2 4.06 3735.7 - 6.43E+06 - - - -0.6016 - 4.022 0.56 - 478.8 1 2 1 -0.0015 20 0 0 0 4.53E+07 4.46E+07 - - - 8.1595 1 221125_WJC_METTL3_EV_vs_WT_F03.24101.24101.3 2.46E-07 16/64 R.STGEAFVQFASQEIAEK[136.11].A "sp|P55795|HNRH2_HUMAN,sp|P31943|HNRH1_HUMAN,tr|E5RGH4|E5RGH4_HUMAN,tr|H0YB39|H0YB39_HUMAN,tr|E5RGV0|E5RGV0_HUMAN,tr|E9PCY7|E9PCY7_HUMAN,tr|D6RIU0|D6RIU0_HUMAN,tr|D6RBM0|D6RBM0_HUMAN,tr|G8JLB6|G8JLB6_HUMAN,tr|E7EN40|E7EN40_HUMAN" 10 1848.8985 1.25 38530 24101 3 1848.897864 617.3068 Heterogeneous nuclear ribonucleoprotein H2 OS=Homo sapiens OX=9606 GN=HNRNPH2 PE=1 SV=1 4.25 3735.8 - 2.17E+07 - - - -0.3489 - 3.262 0.629 - 430.3 1 2 0 -0.0006 17 0 0 0 4.76E+08 3.80E+08 - - - 8.5395 1 221125_WJC_METTL3_EV_vs_WT_F03.24102.24102.3 3.45E-07 24/64 K.VTLENFYSNLIAQHEER[166.11].E sp|Q15208|STK38_HUMAN 1 2072.0202 3.65 38531 24102 3 2072.018806 691.6807 Serine\threonine-protein kinase 38 OS=Homo sapiens OX=9606 GN=STK38 PE=1 SV=1 4.75 3735.8 - 2.10E+07 - - - -0.6916 - 3.888 0.592 - 885.3 1 2 0 -0.0014 17 0 0 0 9.29E+08 2.55E+08 - - - 8.5703 1 221125_WJC_METTL3_EV_vs_WT_F03.24103.24103.2 4.63E-09 14/26 K.QQSEEDLLLQDFSR.N "sp|Q9UNL2|SSRG_HUMAN,tr|C9JA28|C9JA28_HUMAN" 2 1706.8111 1.33 38532 24103 2 1706.811882 854.4128 Translocon-associated protein subunit gamma OS=Homo sapiens OX=9606 GN=SSR3 PE=1 SV=1 3.92 3735.9 - 3.00E+06 - - - 0.4324 - 3.074 0.634 - 924.4 1 2 0 0.0007 14 0 0 0 3.01E+07 2.27E+07 - - - 6.5416 1 221125_WJC_METTL3_EV_vs_WT_F03.24106.24106.2 1.43E-10 22/36 K.ILTATVDNANVLLQIDNAR.L sp|P02533|K1C14_HUMAN 1 2053.1168 999 38535 24106 2 2053.118629 1027.5657 "Keratin, type I cytoskeletal 14 OS=Homo sapiens OX=9606 GN=KRT14 PE=1 SV=4" 4.21 3736.2 - 1.30E+06 - - - 0.9064 - 4.187 0.657 - 1792.9 1 2 0 0.0019 19 0 0 0 2.60E+07 0.00E+00 - - - 7.4136 1 221125_WJC_METTL3_EV_vs_WT_F03.24107.24107.3 4.94E-08 20/64 K.ALESPER[166.11]PFLAILGGAK[136.11].V sp|P00558|PGK1_HUMAN 1 1786.0108 1.37 38536 24107 3 1786.010952 596.3442 Phosphoglycerate kinase 1 OS=Homo sapiens OX=9606 GN=PGK1 PE=1 SV=3 6.19 3736.3 - 993480 - - - 0.0907 - 3.206 0.529 - 424.1 1 2 0 0.0002 17 0 0 0 1.93E+07 1.41E+07 - - - 7.381 0.9999 221125_WJC_METTL3_EV_vs_WT_F03.24110.24110.3 0.000591 15/72 K.DSGPLPTPPGVSLLGEPPK.D "tr|E9PAU2|E9PAU2_HUMAN,tr|A0A087WZ13|A0A087WZ13_HUMAN" 2 1856.9884 0.46 38539 24110 3 1856.992245 620.0034 Ribonucleoprotein PTB-binding 1 OS=Homo sapiens OX=9606 GN=RAVER1 PE=1 SV=1 4.37 3736.7 - 643666 - - - 2.0813 - 2.983 0.445 - 163.9 1 2 0 0.0039 19 0 0 0 8.27E+06 1.79E+07 - - - 6.1854 0.9527 221125_WJC_METTL3_EV_vs_WT_F03.24112.24112.3 1.34 Sep-52 R.YTLNVLEDLGDGQK[136.11].A "sp|P13797|PLST_HUMAN,tr|A0A0A0MSQ0|A0A0A0MSQ0_HUMAN" 2 1571.7923 0.45 38541 24112 3 1571.792271 524.938 Plastin-3 OS=Homo sapiens OX=9606 GN=PLS3 PE=1 SV=4 4.03 3737 - 298538 - - - 0.0115 - 1.666 0.089 - 40.1 1 2 0 0 14 0 0 0 6.11E+05 1.35E+06 - - - 0.8887 1 221125_WJC_METTL3_EV_vs_WT_F03.24115.24115.3 1.11E-12 24/76 K.LQQELEFLEVQEEYIKDEQK.N sp|P43686|PRS6B_HUMAN 1 2537.2537 1.02 38542 24115 3 2537.252181 846.7585 26S proteasome regulatory subunit 6B OS=Homo sapiens OX=9606 GN=PSMC4 PE=1 SV=2 4.06 3737.4 - 6.85E+06 - - - -0.6046 - 4.53 0.646 - 898.8 1 2 1 -0.0015 20 0 0 0 4.53E+07 4.46E+07 - - - 9.4069 0.9999 221125_WJC_METTL3_EV_vs_WT_F03.24118.24118.3 3.68E-09 16/80 K.TPFLLVGTQIDLR[166.11]DDPSTIEK[136.11].L "sp|P60953|CDC42_HUMAN,tr|A0A590UJK8|A0A590UJK8_HUMAN,tr|Q5JYX0|Q5JYX0_HUMAN" 3 2375.2703 1.01 38545 24118 3 2375.26781 792.764 Cell division control protein 42 homolog OS=Homo sapiens OX=9606 GN=CDC42 PE=1 SV=2 4.23 3737.6 - 3.52E+06 - - - -1.0534 - 3.226 0.569 - 236.7 1 2 1 -0.0025 21 0 0 0 2.68E+07 2.65E+07 - - - 7.6911 0.9998 221125_WJC_METTL3_EV_vs_WT_F03.24119.24119.4 7.13E-06 16/132 K.LADVDKDGLLDDEEFALANHLIK.V "sp|Q9H4M9|EHD1_HUMAN,tr|A0A024R571|A0A024R571_HUMAN" 2 2553.2962 1.01 38546 24119 4 2553.29608 639.3313 EH domain-containing protein 1 OS=Homo sapiens OX=9606 GN=EHD1 PE=1 SV=2 4.09 3737.7 - 3.27E+06 - - - -0.0662 - 3.34 0.45 - 146.3 1 2 1 -0.0002 23 0 0 0 2.78E+07 2.76E+07 - - - 3.5335 0.9942 221125_WJC_METTL3_EV_vs_WT_F03.24123.24123.3 0.000728 14/80 K.EAALTSEEVGADLEQVEVLQK.K "sp|Q13813|SPTN1_HUMAN,tr|A0A0D9SF54|A0A0D9SF54_HUMAN,tr|A0A0D9SGF6|A0A0D9SGF6_HUMAN" 3 2257.1325 1.13 38550 24123 3 2257.145514 753.3848 "Spectrin alpha chain, non-erythrocytic 1 OS=Homo sapiens OX=9606 GN=SPTAN1 PE=1 SV=3" 3.83 3737.9 - 2.20E+06 - - - 5.7489 - 2.485 0.341 - 174.8 1 2 0 0.013 21 0 0 0 1.47E+07 1.30E+07 - - - 4.5206 1 221125_WJC_METTL3_EV_vs_WT_F03.24124.24124.3 3.77E-07 Dec-56 K.VEEEIQTLSQVLAAK.E "sp|P55327|TPD52_HUMAN,tr|H0YC44|H0YC44_HUMAN,tr|E5RFR7|E5RFR7_HUMAN,tr|H0YC42|H0YC42_HUMAN" 4 1656.8934 1.47 38551 24124 3 1656.895945 553.3051 Tumor protein D52 OS=Homo sapiens OX=9606 GN=TPD52 PE=1 SV=2 4.25 3738 - 1.92E+06 - - - 1.5257 - 2.781 0.484 - 193.3 1 2 0 0.0025 15 0 0 0 1.15E+07 7.84E+06 - - - 6.6043 0.9999 221125_WJC_METTL3_EV_vs_WT_F03.24125.24125.3 0.000186 23/64 R.RVLQGLEIELQSQLSMK.A "sp|P08779|K1C16_HUMAN,tr|K7ENW6|K7ENW6_HUMAN" 2 1971.0823 0.9 38552 24125 3 1971.08878 658.0347 "Keratin, type I cytoskeletal 16 OS=Homo sapiens OX=9606 GN=KRT16 PE=1 SV=4" 6.14 3738.1 - 1.86E+06 - - - 3.2891 - 3.91 0.527 - 798.3 1 2 0 0.0065 17 0 0 0 1.17E+07 1.30E+07 - - - 7.8584 0.9999 221125_WJC_METTL3_EV_vs_WT_F03.24129.24129.3 0.00221 12/104 R.VVAPTFVPSVEAFDERPGPIQIASQAR.D "sp|O15417|TNC18_HUMAN,tr|H9KVB4|H9KVB4_HUMAN" 2 2880.5134 4.38 38556 24129 3 2880.516188 961.1784 Trinucleotide repeat-containing gene 18 protein OS=Homo sapiens OX=9606 GN=TNRC18 PE=1 SV=3 4.68 3738.4 - 1.45E+06 - - - 0.9703 - 1.925 0.44 - 60.4 1 2 0 0.0028 27 0 0 0 6.75E+06 1.54E+06 - - - 4.9515 1 221125_WJC_METTL3_EV_vs_WT_F03.24130.24130.3 2.35E-06 13/68 K.SGTWWDEHLSEENVPFIK.Q "sp|P09001|RM03_HUMAN,tr|E7ETU7|E7ETU7_HUMAN,tr|H0Y9G6|H0Y9G6_HUMAN,tr|E9PF06|E9PF06_HUMAN" 4 2173.0116 2.55 38557 24130 3 2173.012428 725.3445 "39S ribosomal protein L3, mitochondrial OS=Homo sapiens OX=9606 GN=MRPL3 PE=1 SV=1" 4.4 3738.5 - 1.43E+06 - - - 0.3654 - 2.317 0.479 - 155.1 1 2 0 0.0008 18 0 0 0 1.78E+07 6.98E+06 - - - 5.9725 0.988 221125_WJC_METTL3_EV_vs_WT_F03.24131.24131.2 3.49E-07 13/34 C.GGSIQTSVNALSADVLGR[166.11].C sp|Q99832|TCPH_HUMAN 1 1753.9198 0.04 38558 24131 2 1753.923407 877.9672 T-complex protein 1 subunit eta OS=Homo sapiens OX=9606 GN=CCT7 PE=1 SV=2 5.84 3738.6 - 1.17E+06 - - - 2.0588 - 3.033 0.525 - 403.6 1 1 0 0.0036 18 0 0 0 3.79E+05 1.02E+07 - - - 5.6454 0.9999 221125_WJC_METTL3_EV_vs_WT_F03.24132.24132.2 3.43E-09 14/28 K.VEEEIQTLSQVLAAK[136.11].E "sp|P55327|TPD52_HUMAN,tr|H0YC44|H0YC44_HUMAN,tr|E5RFR7|E5RFR7_HUMAN,tr|H0YC42|H0YC42_HUMAN" 4 1664.9076 1.96 38559 24132 2 1664.905237 833.4611 Tumor protein D52 OS=Homo sapiens OX=9606 GN=TPD52 PE=1 SV=2 4.25 3738.8 - 1.15E+06 - - - -1.4295 - 2.484 0.57 - 571 1 2 0 -0.0024 15 0 0 0 1.82E+07 9.28E+06 - - - 5.4872 0.9999 221125_WJC_METTL3_EV_vs_WT_F03.24133.24133.4 3.30E-05 16/96 K.VTLENFYSNLIAQHEER.E sp|Q15208|STK38_HUMAN 1 2062.012 7.19 38560 24133 4 2062.015661 516.5103 Serine\threonine-protein kinase 38 OS=Homo sapiens OX=9606 GN=STK38 PE=1 SV=1 4.75 3738.9 - 1.09E+06 - - - 1.7905 - 2.744 0.45 - 165.5 1 2 0 0.0037 17 0 0 0 4.86E+06 6.75E+05 - - - 3.4922 1 221125_WJC_METTL3_EV_vs_WT_F03.24134.24134.4 1.90E-08 19/78 R.LIILDEIHLLHDDR.G "sp|O75643|U520_HUMAN,tr|A0A494C1A5|A0A494C1A5_HUMAN" 2 1713.9414 2.03 38561 24134 4 1713.938392 429.4926 U5 small nuclear ribonucleoprotein 200 kDa helicase OS=Homo sapiens OX=9606 GN=SNRNP200 PE=1 SV=2 4.64 3739 - 613439 - - - -1.7375 - 2.995 0.614 - 318.1 1 2 0 -0.003 14 0 0 0 7.39E+06 3.64E+06 - - - 4.9687 1 221125_WJC_METTL3_EV_vs_WT_F03.24136.24136.4 1.29E-06 14/78 R.LIILDEIHLLHDDR[166.11].G "sp|O75643|U520_HUMAN,tr|A0A494C1A5|A0A494C1A5_HUMAN" 2 1723.9496 2.03 38562 24136 4 1723.950584 431.9947 U5 small nuclear ribonucleoprotein 200 kDa helicase OS=Homo sapiens OX=9606 GN=SNRNP200 PE=1 SV=2 4.64 3739.3 - 738599 - - - 0.5476 - 2.617 0.548 - 146.2 1 2 0 0.0009 14 0 0 0 7.39E+06 3.64E+06 - - - 4.3457 1 221125_WJC_METTL3_EV_vs_WT_F03.24140.24140.3 1.09E-05 17/48 K.SEISQVFEIALKR.N "sp|O95793|STAU1_HUMAN,tr|Q5JW30|Q5JW30_HUMAN,tr|Q5JW28|Q5JW28_HUMAN" 3 1518.8406 1.78 38565 24140 3 1518.839379 507.2875 Double-stranded RNA-binding protein Staufen homolog 1 OS=Homo sapiens OX=9606 GN=STAU1 PE=1 SV=2 5.86 3739.6 - 4.36E+06 - - - -0.7993 - 3.244 0.558 - 437.1 1 2 0 -0.0012 13 0 0 0 4.81E+07 2.71E+07 - - - 7.9515 1 221125_WJC_METTL3_EV_vs_WT_F03.24141.24141.3 8.46E-07 15/48 K.SEISQVFEIALK[136.11]R[166.11].N "sp|O95793|STAU1_HUMAN,tr|Q5JW30|Q5JW30_HUMAN,tr|Q5JW28|Q5JW28_HUMAN" 3 1536.8631 1.79 38566 24141 3 1536.861698 513.295 Double-stranded RNA-binding protein Staufen homolog 1 OS=Homo sapiens OX=9606 GN=STAU1 PE=1 SV=2 5.86 3739.6 - 3.35E+06 - - - -0.8882 - 2.765 0.573 - 346.3 1 2 0 -0.0014 13 0 0 0 4.87E+07 2.72E+07 - - - 7.6855 0.9999 221125_WJC_METTL3_EV_vs_WT_F03.24142.24142.3 1.24E-07 13/68 K.SGTWWDEHLSEENVPFIK[136.11].Q "sp|P09001|RM03_HUMAN,tr|E7ETU7|E7ETU7_HUMAN,tr|H0Y9G6|H0Y9G6_HUMAN,tr|E9PF06|E9PF06_HUMAN" 4 2181.0258 2.5 38567 24142 3 2181.019769 728.0159 "39S ribosomal protein L3, mitochondrial OS=Homo sapiens OX=9606 GN=MRPL3 PE=1 SV=1" 4.4 3739.7 - 2.87E+06 - - - -2.7808 - 2.27 0.555 - 159.4 1 2 0 -0.0061 18 0 0 0 1.74E+07 6.98E+06 - - - 6.7674 0.967 221125_WJC_METTL3_EV_vs_WT_F03.24144.24144.3 1.70E-06 15/80 K.EAALTSEEVGADLEQVEVLQK[136.11].K "sp|Q13813|SPTN1_HUMAN,tr|A0A0D9SF54|A0A0D9SF54_HUMAN,tr|A0A0D9SGF6|A0A0D9SGF6_HUMAN" 3 2265.1467 1.75 38569 24144 3 2266.136165 756.0562 "Spectrin alpha chain, non-erythrocytic 1 OS=Homo sapiens OX=9606 GN=SPTAN1 PE=1 SV=3" 3.83 3739.8 - 1.74E+06 - - - 436.8048 - 2.97 0.495 - 353.4 1 2 0 0.9894 21 0 0 0 2.62E+07 1.50E+07 - - - 6.3945 1 221125_WJC_METTL3_EV_vs_WT_F03.24146.24146.3 1.62E-08 14/56 R.TVESEAASYLDQISR.Y "sp|P61289|PSME3_HUMAN,tr|K7ENH2|K7ENH2_HUMAN,tr|B3KQ25|B3KQ25_HUMAN,tr|K7ESG5|K7ESG5_HUMAN,tr|K9J957|K9J957_HUMAN,tr|A0A087WTV2|A0A087WTV2_HUMAN" 6 1667.8002 1.52 38571 24146 3 1667.802264 556.9407 Proteasome activator complex subunit 3 OS=Homo sapiens OX=9606 GN=PSME3 PE=1 SV=1 4.14 3740 - 1.44E+06 - - - 1.2106 - 2.599 0.615 - 221.3 1 2 0 0.002 15 0 0 0 5.97E+07 3.93E+07 - - - 7.8884 1 221125_WJC_METTL3_EV_vs_WT_F03.24147.24147.3 1.66E-06 14/56 R.TVESEAASYLDQISR[166.11].Y "sp|P61289|PSME3_HUMAN,tr|K7ENH2|K7ENH2_HUMAN,tr|B3KQ25|B3KQ25_HUMAN,tr|K7ESG5|K7ESG5_HUMAN,tr|K9J957|K9J957_HUMAN,tr|A0A087WTV2|A0A087WTV2_HUMAN" 6 1677.8085 1.51 38572 24147 3 1677.806597 560.2768 Proteasome activator complex subunit 3 OS=Homo sapiens OX=9606 GN=PSME3 PE=1 SV=1 4.14 3740.1 - 1.36E+06 - - - -1.1432 - 2.301 0.587 - 170.7 1 2 0 -0.0019 15 0 0 0 5.93E+07 3.93E+07 - - - 7.2584 1 221125_WJC_METTL3_EV_vs_WT_F03.24148.24148.2 4.77E-09 19/28 K.HSQFLGYPITLYLEK.E "sp|Q58FF8|H90B2_HUMAN,sp|P08238|HS90B_HUMAN,sp|Q58FF7|H90B3_HUMAN" 3 1807.9509 3.53 38573 24148 2 1807.950473 904.9827 Putative heat shock protein HSP 90-beta 2 OS=Homo sapiens OX=9606 GN=HSP90AB2P PE=1 SV=2 6.75 3740.2 - 979976 - - - -0.2207 - 4.144 0.663 - 1334.2 1 2 0 -0.0004 15 0 0 0 1.11E+07 3.14E+06 - - - 7.433 0.9996 221125_WJC_METTL3_EV_vs_WT_F03.24151.24151.3 0.00591 Sep-56 R.GGDDLGTEIANTLYR[166.11].L sp|Q15024|EXOS7_HUMAN 1 1603.7717 1.71 38576 24151 3 1603.771256 535.5979 Exosome complex component RRP42 OS=Homo sapiens OX=9606 GN=EXOSC7 PE=1 SV=3 4.03 3740.6 - 509077 - - - -0.2987 - 1.803 0.346 - 69.9 1 2 0 -0.0005 15 0 0 0 3.66E+06 2.13E+06 - - - 3.9355 1 221125_WJC_METTL3_EV_vs_WT_F03.24155.24155.4 6.06E-06 22/114 K.TLAYLLPAIVHINHQPYLER[166.11].G "sp|Q92841|DDX17_HUMAN,tr|A0A5H1ZRQ2|A0A5H1ZRQ2_HUMAN,tr|A0A1X7SBZ2|A0A1X7SBZ2_HUMAN" 3 2370.3088 1.12 38578 24155 4 2370.308808 593.5845 Probable ATP-dependent RNA helicase DDX17 OS=Homo sapiens OX=9606 GN=DDX17 PE=1 SV=2 6.61 3741.1 - 2.39E+06 - - - 0.0215 - 3.387 0.549 - 214.9 1 2 0 0.0001 20 0 0 0 1.29E+08 1.16E+08 - - - 4.4123 0.9993 221125_WJC_METTL3_EV_vs_WT_F03.24156.24156.2 0.414 16-Jun K.DAEEWFFTK.T sp|P02533|K1C14_HUMAN 1 1171.5186 248.62 38579 24156 2 1171.518122 586.7666 "Keratin, type I cytoskeletal 14 OS=Homo sapiens OX=9606 GN=KRT14 PE=1 SV=4" 4.14 3741.1 - 2.34E+06 - - - -0.3995 - 1.666 0.291 - 132.6 1 2 0 -0.0005 9 0 0 0 3.85E+07 1.55E+05 - - - 2.6669 1 221125_WJC_METTL3_EV_vs_WT_F03.24157.24157.2 6.57E-13 21/36 R.YEGILYTIDTENSTVALAK.V "sp|Q8ND56|LS14A_HUMAN,tr|I3L4Q1|I3L4Q1_HUMAN,tr|A0A140TA76|A0A140TA76_HUMAN,tr|K7EMZ9|K7EMZ9_HUMAN" 4 2100.0627 1.07 38580 24157 2 2100.06395 1051.0386 Protein LSM14 homolog A OS=Homo sapiens OX=9606 GN=LSM14A PE=1 SV=3 4.14 3741.3 - 2.11E+06 - - - 0.6109 - 3.933 0.695 - 1266 1 2 0 0.0013 19 0 0 0 7.57E+07 7.05E+07 - - - 7.5406 1 221125_WJC_METTL3_EV_vs_WT_F03.24158.24158.2 4.89E-12 25/38 R.ISLGLPVGAVINC[160.03]ADNTGAK.N "sp|P62829|RL23_HUMAN,tr|J3KT29|J3KT29_HUMAN,tr|B9ZVP7|B9ZVP7_HUMAN,tr|C9JD32|C9JD32_HUMAN" 4 1969.0303 1.14 38581 24158 2 1969.030359 985.5224 60S ribosomal protein L23 OS=Homo sapiens OX=9606 GN=RPL23 PE=1 SV=1 5.83 3741.4 - 2.06E+06 - - - 0.0493 - 3.727 0.688 - 1583.9 1 2 0 0.0001 20 0 0 0 2.00E+09 1.76E+09 - - - 7.357 1 221125_WJC_METTL3_EV_vs_WT_F03.24159.24159.3 1.15E-08 22/80 K.DLYANTVLSGGTTMYPGIADR[166.11].M "sp|P63261|ACTG_HUMAN,sp|P60709|ACTB_HUMAN,tr|A0A804GS07|A0A804GS07_HUMAN,tr|E7EVS6|E7EVS6_HUMAN,tr|A0A6Q8PFE4|A0A6Q8PFE4_HUMAN,tr|A0A2R8Y793|A0A2R8Y793_HUMAN,tr|I3L4N8|I3L4N8_HUMAN" 7 2224.071 4.59 38582 24159 3 2224.066354 742.3643 "Actin, cytoplasmic 2 OS=Homo sapiens OX=9606 GN=ACTG1 PE=1 SV=1" 4.21 3741.4 - 1.91E+06 - - - -2.0683 - 3.981 0.623 - 441.7 1 2 0 -0.0046 21 0 0 0 1.35E+08 2.94E+07 - - - 8.7967 1 221125_WJC_METTL3_EV_vs_WT_F03.24161.24161.3 8.95E-09 20/80 K.DLYANTVLSGGTTMYPGIADR.M "sp|P63261|ACTG_HUMAN,sp|P60709|ACTB_HUMAN,tr|A0A804GS07|A0A804GS07_HUMAN,tr|E7EVS6|E7EVS6_HUMAN,tr|A0A6Q8PFE4|A0A6Q8PFE4_HUMAN,tr|A0A2R8Y793|A0A2R8Y793_HUMAN,tr|I3L4N8|I3L4N8_HUMAN" 7 2214.0627 4.43 38584 24161 3 2214.063973 739.0282 "Actin, cytoplasmic 2 OS=Homo sapiens OX=9606 GN=ACTG1 PE=1 SV=1" 4.21 3741.6 - 1.75E+06 - - - 0.5822 - 3.511 0.602 - 285.3 1 2 0 0.0013 21 0 0 0 1.36E+08 3.07E+07 - - - 8.2623 1 221125_WJC_METTL3_EV_vs_WT_F03.24164.24164.2 1.42E-07 17/28 R.TVESEAASYLDQISR.Y "sp|P61289|PSME3_HUMAN,tr|K7ENH2|K7ENH2_HUMAN,tr|B3KQ25|B3KQ25_HUMAN,tr|K7ESG5|K7ESG5_HUMAN,tr|K9J957|K9J957_HUMAN,tr|A0A087WTV2|A0A087WTV2_HUMAN" 6 1667.8002 1.23 38587 24164 2 1667.794722 834.9074 Proteasome activator complex subunit 3 OS=Homo sapiens OX=9606 GN=PSME3 PE=1 SV=1 4.14 3742 - 1.58E+06 - - - -3.3115 - 3.304 0.642 - 893.4 1 2 0 -0.0055 15 0 0 0 2.51E+07 2.04E+07 - - - 6.7194 1 221125_WJC_METTL3_EV_vs_WT_F03.24166.24166.3 2.91E-08 15/52 K.GTHFNFAIVFTDVK[136.11].R "sp|O00422|SAP18_HUMAN,tr|U3KPY7|U3KPY7_HUMAN,tr|H7BZW6|H7BZW6_HUMAN" 3 1602.8286 1.46 38589 24166 3 1602.829055 535.2835 Histone deacetylase complex subunit SAP18 OS=Homo sapiens OX=9606 GN=SAP18 PE=1 SV=1 6.74 3742.3 - 671981 - - - 0.2976 - 2.725 0.56 - 317.6 1 2 0 0.0005 14 0 0 0 5.33E+07 3.65E+07 - - - 7.4474 1 221125_WJC_METTL3_EV_vs_WT_F03.24171.24171.3 2.65E-12 21/76 R.ISLGLPVGAVINC[160.03]ADNTGAK[136.11].N "sp|P62829|RL23_HUMAN,tr|J3KT29|J3KT29_HUMAN,tr|B9ZVP7|B9ZVP7_HUMAN,tr|C9JD32|C9JD32_HUMAN" 4 1977.0445 1.1 38592 24171 3 1977.043465 660.0221 60S ribosomal protein L23 OS=Homo sapiens OX=9606 GN=RPL23 PE=1 SV=1 5.83 3742.9 - 1.95E+07 - - - -0.5043 - 3.649 0.644 - 524.9 1 2 0 -0.001 20 0 0 0 2.05E+09 1.86E+09 - - - 8.8601 1 221125_WJC_METTL3_EV_vs_WT_F03.24172.24172.3 4.62E-12 22/76 R.ISLGLPVGAVINC[160.03]ADNTGAK.N "sp|P62829|RL23_HUMAN,tr|J3KT29|J3KT29_HUMAN,tr|B9ZVP7|B9ZVP7_HUMAN,tr|C9JD32|C9JD32_HUMAN" 4 1969.0303 1.1 38593 24172 3 1969.031078 657.3507 60S ribosomal protein L23 OS=Homo sapiens OX=9606 GN=RPL23 PE=1 SV=1 5.83 3743 - 1.81E+07 - - - 0.4144 - 3.689 0.688 - 646.9 1 2 0 0.0008 20 0 0 0 2.05E+09 1.86E+09 - - - 9.3771 1 221125_WJC_METTL3_EV_vs_WT_F03.24173.24173.3 1.27E-07 17/64 R.QEIEC[160.03]QNQEYSLLLSIK.M "sp|P35527|K1C9_HUMAN,tr|K7EQQ3|K7EQQ3_HUMAN" 2 2094.0303 1224.56 38594 24173 3 2094.031266 699.0174 "Keratin, type I cytoskeletal 9 OS=Homo sapiens OX=9606 GN=KRT9 PE=1 SV=3" 4.25 3743 - 1.52E+07 - - - 0.4513 - 3.499 0.636 - 500.7 1 2 0 0.0009 17 0 0 0 2.18E+09 1.78E+06 - - - 8.7946 1 221125_WJC_METTL3_EV_vs_WT_F03.24174.24174.2 1.01E-06 18/32 R.QEIEC[160.03]QNQEYSLLLSIK.M "sp|P35527|K1C9_HUMAN,tr|K7EQQ3|K7EQQ3_HUMAN" 2 2094.0303 999 38595 24174 2 2094.031226 1048.0224 "Keratin, type I cytoskeletal 9 OS=Homo sapiens OX=9606 GN=KRT9 PE=1 SV=3" 4.25 3743.1 - 6.47E+06 - - - 0.4322 - 3.96 0.698 - 1195.3 1 2 0 0.0009 17 0 0 0 1.17E+09 0.00E+00 - - - 7.5797 1 221125_WJC_METTL3_EV_vs_WT_F03.24178.24178.3 1.22E-08 17/52 K.GTHFNFAIVFTDVK.R "sp|O00422|SAP18_HUMAN,tr|U3KPY7|U3KPY7_HUMAN,tr|H7BZW6|H7BZW6_HUMAN" 3 1594.8144 1.46 38599 24178 3 1594.81569 532.6121 Histone deacetylase complex subunit SAP18 OS=Homo sapiens OX=9606 GN=SAP18 PE=1 SV=1 6.74 3743.4 - 1.67E+06 - - - 0.8227 - 2.86 0.594 - 429.6 1 2 0 0.0013 14 0 0 0 5.33E+07 3.65E+07 - - - 7.9547 1 221125_WJC_METTL3_EV_vs_WT_F03.24181.24181.3 1.64E-13 17/96 K.MLETC[160.03]GDAENQLALELSQHEVFVEK.E "sp|Q68EM7|RHG17_HUMAN,tr|C9IZD3|C9IZD3_HUMAN,tr|I3L4P6|I3L4P6_HUMAN" 3 2889.3525 2.16 38602 24181 3 2889.342642 964.1248 Rho GTPase-activating protein 17 OS=Homo sapiens OX=9606 GN=ARHGAP17 PE=1 SV=1 4.14 3743.7 - 886528 - - - -3.398 - 3.382 0.683 - 172.2 1 2 0 -0.0098 25 0 0 0 6.08E+06 2.81E+06 - - - 8.9553 1 221125_WJC_METTL3_EV_vs_WT_F03.24182.24182.2 2.99E-09 20/40 K.DLYANTVLSGGTTMYPGIADR.M "sp|P63261|ACTG_HUMAN,sp|P60709|ACTB_HUMAN,tr|A0A804GS07|A0A804GS07_HUMAN,tr|E7EVS6|E7EVS6_HUMAN,tr|A0A6Q8PFE4|A0A6Q8PFE4_HUMAN,tr|A0A2R8Y793|A0A2R8Y793_HUMAN,tr|I3L4N8|I3L4N8_HUMAN" 7 2214.0627 2.1 38603 24182 2 2214.06368 1108.0386 "Actin, cytoplasmic 2 OS=Homo sapiens OX=9606 GN=ACTG1 PE=1 SV=1" 4.21 3743.9 - 768752 - - - 0.4499 - 4.149 0.698 - 963 1 2 0 0.001 21 0 0 0 1.20E+07 5.71E+06 - - - 7.6943 1 221125_WJC_METTL3_EV_vs_WT_F03.24183.24183.2 4.85E-11 18/36 K.VIEDVAFAC[160.03]ALTSSVPTTK[136.11].K "sp|Q14527|HLTF_HUMAN,tr|A0A0C4DGA6|A0A0C4DGA6_HUMAN" 2 2016.0329 -1 38604 24183 2 2016.029255 1009.0237 Helicase-like transcription factor OS=Homo sapiens OX=9606 GN=HLTF PE=1 SV=2 4.37 3744 - 555190 - - - -1.805 - 3.263 0.684 - 680.7 1 2 0 -0.0036 19 0 0 0 0.00E+00 0.00E+00 - - - 6.9995 1 221125_WJC_METTL3_EV_vs_WT_F03.24185.24185.3 2.20E-09 17/72 R.YEGILYTIDTENSTVALAK[136.11].V "sp|Q8ND56|LS14A_HUMAN,tr|I3L4Q1|I3L4Q1_HUMAN,tr|A0A140TA76|A0A140TA76_HUMAN,tr|K7EMZ9|K7EMZ9_HUMAN" 4 2108.0769 0.86 38605 24185 3 2108.076406 703.6996 Protein LSM14 homolog A OS=Homo sapiens OX=9606 GN=LSM14A PE=1 SV=3 4.14 3744.2 - 8.40E+06 - - - -0.2187 - 3.454 0.596 - 515.1 1 2 0 -0.0005 19 0 0 0 7.12E+07 8.32E+07 - - - 8.23 1 221125_WJC_METTL3_EV_vs_WT_F03.24186.24186.3 7.31E-06 17/68 K.DNHLLGTFDLTGIPPAPR[166.11].G "sp|P11021|BIP_HUMAN,tr|A0A7P0TAI0|A0A7P0TAI0_HUMAN" 2 1943.014 0.58 38606 24186 3 1943.014615 648.6786 Endoplasmic reticulum chaperone BiP OS=Homo sapiens OX=9606 GN=HSPA5 PE=1 SV=2 5.21 3744.3 - 2.51E+06 - - - 0.3006 - 3.299 0.501 - 254 1 2 0 0.0006 18 0 0 0 3.42E+07 5.88E+07 - - - 7.0977 1 221125_WJC_METTL3_EV_vs_WT_F03.24187.24187.3 3.53E-08 24/84 K.QAAAAAAAAAATAAWTGTTFTK.K sp|Q96KR1|ZFR_HUMAN 1 2022.0171 1.45 38607 24187 3 2022.022565 675.013 Zinc finger RNA-binding protein OS=Homo sapiens OX=9606 GN=ZFR PE=1 SV=2 8.75 3744.3 - 4.62E+06 - - - 2.7255 - 4.429 0.602 - 888.3 1 2 0 0.0055 22 0 0 0 5.37E+07 3.70E+07 - - - 8.7784 1 221125_WJC_METTL3_EV_vs_WT_F03.24189.24189.2 2.47E-07 15/28 R.TVESEAASYLDQISR[166.11].Y "sp|P61289|PSME3_HUMAN,tr|K7ENH2|K7ENH2_HUMAN,tr|B3KQ25|B3KQ25_HUMAN,tr|K7ESG5|K7ESG5_HUMAN,tr|K9J957|K9J957_HUMAN,tr|A0A087WTV2|A0A087WTV2_HUMAN" 6 1677.8085 1.23 38609 24189 2 1677.802224 839.9115 Proteasome activator complex subunit 3 OS=Homo sapiens OX=9606 GN=PSME3 PE=1 SV=1 4.14 3744.5 - 1.94E+06 - - - -3.7495 - 3.278 0.665 - 781.6 1 2 0 -0.0063 15 0 0 0 2.51E+07 2.04E+07 - - - 6.8696 1 221125_WJC_METTL3_EV_vs_WT_F03.24194.24194.3 7.25E-07 24/76 K.TLAYLLPAIVHINHQPYLER[166.11].G "sp|Q92841|DDX17_HUMAN,tr|A0A5H1ZRQ2|A0A5H1ZRQ2_HUMAN,tr|A0A1X7SBZ2|A0A1X7SBZ2_HUMAN" 3 2370.3088 1.01 38614 24194 3 2370.309742 791.1102 Probable ATP-dependent RNA helicase DDX17 OS=Homo sapiens OX=9606 GN=DDX17 PE=1 SV=2 6.61 3745 - 1.16E+06 - - - 0.4156 - 3.682 0.616 - 589 1 2 0 0.001 20 0 0 0 2.58E+07 2.54E+07 - - - 8.5697 0.9986 221125_WJC_METTL3_EV_vs_WT_F03.24195.24195.3 9.28E-05 14/52 K.EDLTEIRDMLLANK.V "sp|Q8NHW5|RLA0L_HUMAN,sp|P05388|RLA0_HUMAN,tr|G3V210|G3V210_HUMAN,tr|F8VU65|F8VU65_HUMAN,tr|F8VWV4|F8VWV4_HUMAN,tr|F8VWS0|F8VWS0_HUMAN,tr|F8VS58|F8VS58_HUMAN,tr|F8VW21|F8VW21_HUMAN,tr|F8VZS0|F8VZS0_HUMAN,tr|F8VRK7|F8VRK7_HUMAN,tr|F8VQY6|F8VQY6_HUMAN,tr|F8VPE8|F8VPE8_HUMAN" 12 1659.8502 1.21 38615 24195 3 1659.84933 554.2907 60S acidic ribosomal protein P0-like OS=Homo sapiens OX=9606 GN=RPLP0P6 PE=5 SV=1 4.32 3745.1 - 1.01E+06 - - - -0.5073 - 2.294 0.309 - 241.2 1 2 1 -0.0008 14 0 0 0 1.94E+07 1.61E+07 - - - 4.1914 0.9967 221125_WJC_METTL3_EV_vs_WT_F03.24197.24197.3 1.46E-10 17/60 G.KSVISGGLDALEFIGK.K "sp|Q9NRY5|F1142_HUMAN,tr|E7ESJ7|E7ESJ7_HUMAN,tr|E5RGF9|E5RGF9_HUMAN" 3 1632.9087 0.98 38617 24197 3 1632.913076 545.3102 Protein FAM114A2 OS=Homo sapiens OX=9606 GN=FAM114A2 PE=1 SV=4 6.07 3745.3 - 560860 - - - 2.6964 - 3.35 0.595 - 444.3 1 1 0 0.0044 16 0 0 0 5.20E+06 5.29E+06 - - - 8.2745 1 221125_WJC_METTL3_EV_vs_WT_F03.24202.24202.2 6.49E-09 18/38 R.ISLGLPVGAVINC[160.03]ADNTGAK[136.11].N "sp|P62829|RL23_HUMAN,tr|J3KT29|J3KT29_HUMAN,tr|B9ZVP7|B9ZVP7_HUMAN,tr|C9JD32|C9JD32_HUMAN" 4 1977.0445 1.14 38620 24202 2 1977.041837 989.5295 60S ribosomal protein L23 OS=Homo sapiens OX=9606 GN=RPL23 PE=1 SV=1 5.83 3746 - 5.75E+07 - - - -1.3277 - 3.028 0.642 - 782 1 2 0 -0.0026 20 0 0 0 2.00E+09 1.76E+09 - - - 6.5058 1 221125_WJC_METTL3_EV_vs_WT_F03.24204.24204.3 0.000199 Sep-56 R.TVYFSEQWVSSLNER.E "sp|P52732|KIF11_HUMAN,tr|A0A7I2V3A9|A0A7I2V3A9_HUMAN" 2 1843.8741 5.25 38622 24204 3 1843.872551 615.632 Kinesin-like protein KIF11 OS=Homo sapiens OX=9606 GN=KIF11 PE=1 SV=2 4.53 3746.1 - 3.80E+06 - - - -0.8281 - 2.255 0.533 - 91.7 1 2 0 -0.0015 15 0 0 0 6.46E+07 1.23E+07 - - - 6.6038 1 221125_WJC_METTL3_EV_vs_WT_F03.24206.24206.3 3.24E-09 16/88 R.YNEETFGYEVPIKEEGDYVLVLK.F "sp|Q14165|MLEC_HUMAN,tr|F5GX14|F5GX14_HUMAN,tr|F5H1S8|F5H1S8_HUMAN" 3 2733.3425 1.28 38624 24206 3 2733.344958 912.1215 Malectin OS=Homo sapiens OX=9606 GN=MLEC PE=1 SV=1 4.14 3746.3 - 1.07E+06 - - - 0.8883 - 3.437 0.629 - 162.2 1 2 1 0.0024 23 0 0 0 1.84E+07 1.44E+07 - - - 8.4484 0.9999 221125_WJC_METTL3_EV_vs_WT_F03.24207.24207.3 7.10E-05 Dec-48 R.QSLVELLIRPVQR.L sp|Q9H8V3|ECT2_HUMAN 1 1549.9304 0.93 38625 24207 3 1549.931128 517.6507 Protein ECT2 OS=Homo sapiens OX=9606 GN=ECT2 PE=1 SV=4 9.6 3746.4 - 870470 - - - 0.4626 - 2.135 0.456 - 259.2 1 2 0 0.0007 13 0 0 0 7.98E+06 8.54E+06 - - - 5.6802 0.9996 221125_WJC_METTL3_EV_vs_WT_F03.24208.24208.3 0.0018 13/48 R.QSLVELLIR[166.11]PVQR[166.11].L sp|Q9H8V3|ECT2_HUMAN 1 1569.947 0.96 38626 24208 3 1569.946454 524.3229 Protein ECT2 OS=Homo sapiens OX=9606 GN=ECT2 PE=1 SV=4 9.6 3746.6 - 801383 - - - -0.3166 - 2.165 0.298 - 292.9 1 2 0 -0.0005 13 0 0 0 8.22E+06 8.54E+06 - - - 3.9565 0.9943 221125_WJC_METTL3_EV_vs_WT_F03.24210.24210.3 4.20E-09 13/60 G.K[136.11]SVISGGLDALEFIGK[136.11].K "sp|Q9NRY5|F1142_HUMAN,tr|E7ESJ7|E7ESJ7_HUMAN,tr|E5RGF9|E5RGF9_HUMAN" 3 1648.9371 1.05 38628 24210 3 1648.937221 550.653 Protein FAM114A2 OS=Homo sapiens OX=9606 GN=FAM114A2 PE=1 SV=4 6.07 3746.8 - 579240 - - - 0.0898 - 2.45 0.446 - 124.1 1 1 0 0.0001 16 0 0 0 5.53E+06 5.29E+06 - - - 5.8117 1 221125_WJC_METTL3_EV_vs_WT_F03.24212.24212.3 3.13E-06 15/68 K.DNHLLGTFDLTGIPPAPR.G "sp|P11021|BIP_HUMAN,tr|A0A7P0TAI0|A0A7P0TAI0_HUMAN" 2 1933.0058 0.56 38629 24212 3 1933.003623 645.3425 Endoplasmic reticulum chaperone BiP OS=Homo sapiens OX=9606 GN=HSPA5 PE=1 SV=2 5.21 3747 - 1.13E+06 - - - -1.106 - 2.776 0.568 - 164.4 1 2 0 -0.0021 18 0 0 0 2.54E+07 4.54E+07 - - - 7.4145 1 221125_WJC_METTL3_EV_vs_WT_F03.24219.24219.3 1.54E-11 25/76 K.TLAYLLPAIVHINHQPYLER.G "sp|Q92841|DDX17_HUMAN,tr|A0A5H1ZRQ2|A0A5H1ZRQ2_HUMAN,tr|A0A1X7SBZ2|A0A1X7SBZ2_HUMAN" 3 2360.3005 1.01 38634 24219 3 2360.295718 787.7741 Probable ATP-dependent RNA helicase DDX17 OS=Homo sapiens OX=9606 GN=DDX17 PE=1 SV=2 6.61 3747.7 - 2.03E+06 - - - -2.0205 - 3.907 0.575 - 708.1 1 2 0 -0.0048 20 0 0 0 2.58E+07 2.54E+07 - - - 8.2555 1 221125_WJC_METTL3_EV_vs_WT_F03.24220.24220.3 7.06E-09 21/80 K.LAQQYYLVYQEPIPTAQLVQR[166.11].V "sp|P25787|PSA2_HUMAN,tr|A0A024RA52|A0A024RA52_HUMAN,tr|A0A7I2V2H3|A0A7I2V2H3_HUMAN,tr|C9JCK5|C9JCK5_HUMAN,tr|A0A7I2YQP7|A0A7I2YQP7_HUMAN" 5 2530.3459 0.74 38635 24220 3 2530.343251 844.4559 Proteasome subunit alpha type-2 OS=Homo sapiens OX=9606 GN=PSMA2 PE=1 SV=2 6 3747.8 - 1.77E+06 - - - -1.0587 - 3.301 0.542 - 418.6 1 2 0 -0.0027 21 0 0 0 1.49E+07 2.00E+07 - - - 7.4451 1 221125_WJC_METTL3_EV_vs_WT_F03.24221.24221.3 4.04E-09 18/80 K.LAQQYYLVYQEPIPTAQLVQR.V "sp|P25787|PSA2_HUMAN,tr|A0A024RA52|A0A024RA52_HUMAN,tr|A0A7I2V2H3|A0A7I2V2H3_HUMAN,tr|C9JCK5|C9JCK5_HUMAN,tr|A0A7I2YQP7|A0A7I2YQP7_HUMAN" 5 2520.3377 0.74 38636 24221 3 2520.344172 841.1198 Proteasome subunit alpha type-2 OS=Homo sapiens OX=9606 GN=PSMA2 PE=1 SV=2 6 3747.9 - 1.26E+06 - - - 2.5838 - 2.934 0.614 - 293.9 1 2 0 0.0065 21 0 0 0 1.49E+07 2.00E+07 - - - 7.9642 1 221125_WJC_METTL3_EV_vs_WT_F03.24222.24222.2 5.98E-11 19/38 K.VAGPNGYAILLAVPGSSDSR.S "sp|Q96T37|RBM15_HUMAN,tr|A0A494C001|A0A494C001_HUMAN,tr|A0A499FJY3|A0A499FJY3_HUMAN,tr|A0A087WWP4|A0A087WWP4_HUMAN" 4 1943.0112 1.86 38637 24222 2 1943.009209 972.5129 RNA-binding protein 15 OS=Homo sapiens OX=9606 GN=RBM15 PE=1 SV=2 5.81 3748.1 - 683253 - - - -1.0453 - 3.112 0.641 - 728.4 1 2 0 -0.002 20 0 0 0 9.82E+06 5.29E+06 - - - 6.5659 0.9996 221125_WJC_METTL3_EV_vs_WT_F03.24228.24228.2 2.72E-09 13/26 R.EEQIVQLLNSVQAK.N "sp|Q9H2U1|DHX36_HUMAN,tr|E7EWK3|E7EWK3_HUMAN" 2 1597.8675 1.28 38641 24228 2 1597.872463 799.941 ATP-dependent DNA\RNA helicase DHX36 OS=Homo sapiens OX=9606 GN=DHX36 PE=1 SV=2 4.53 3748.9 - 526371 - - - 3.0835 - 2.85 0.509 - 538.2 1 2 0 0.0049 14 0 0 0 2.06E+07 1.60E+07 - - - 5.4271 1 221125_WJC_METTL3_EV_vs_WT_F03.24229.24229.3 2.40E-05 14/48 R.NSILAQVLDQSAR.A "sp|O14737|PDCD5_HUMAN,tr|K7ESJ4|K7ESJ4_HUMAN,tr|K7EQA1|K7EQA1_HUMAN" 3 1413.7576 1.52 38642 24229 3 1413.757967 472.2598 Programmed cell death protein 5 OS=Homo sapiens OX=9606 GN=PDCD5 PE=1 SV=3 5.84 3749 - 501513 - - - 0.2653 - 2.716 0.476 - 384.9 1 2 0 0.0004 13 0 0 0 1.19E+07 7.84E+06 - - - 6.5558 0.9755 221125_WJC_METTL3_EV_vs_WT_F03.24232.24232.2 0.0331 20-Nov K.K[136.11]VSQEILELLN.T "sp|Q86U44|MTA70_HUMAN,tr|H0YFV6|H0YFV6_HUMAN" 2 1292.7431 0.04 38643 24232 2 1292.742436 647.3788 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 4.53 3749.4 - 1.08E+07 - - - -0.5268 - 1.95 0.324 - 429.7 1 1 0 -0.0007 11 0 0 0 1.67E+07 4.62E+08 - - - 3.2405 1 221125_WJC_METTL3_EV_vs_WT_F03.24233.24233.3 1.56E-06 18/52 R.AQLADSFHLQQFFR[166.11].D "sp|Q13813|SPTN1_HUMAN,tr|A0A0D9SF54|A0A0D9SF54_HUMAN,tr|A0A0D9SGF6|A0A0D9SGF6_HUMAN" 3 1716.8612 1.35 38644 24233 3 1716.859485 573.2943 "Spectrin alpha chain, non-erythrocytic 1 OS=Homo sapiens OX=9606 GN=SPTAN1 PE=1 SV=3" 6.79 3749.4 - 2.32E+06 - - - -0.975 - 3.193 0.473 - 491.8 1 2 0 -0.0017 14 0 0 0 5.16E+07 3.83E+07 - - - 6.8983 0.9994 221125_WJC_METTL3_EV_vs_WT_F03.24235.24235.2 1.97E-05 Nov-34 K.SSASAPDVDDPEAFPALA.- sp|Q8NC51|PAIRB_HUMAN 1 1758.7948 - 38646 24235 2 1758.790096 880.4047 Plasminogen activator inhibitor 1 RNA-binding protein OS=Homo sapiens OX=9606 GN=SERBP1 PE=1 SV=2 3.37 3749.7 - 1.30E+06 - - - -2.6888 - 1.753 0.518 - 156.1 1 2 0 -0.0047 18 0 0 0 - - - - - 4.2455 0.9994 221125_WJC_METTL3_EV_vs_WT_F03.24236.24236.3 0.000644 Nov-48 K.EIEELK[136.11]ELLPEIR[166.11].E "sp|P49321|NASP_HUMAN,tr|H0YDS9|H0YDS9_HUMAN,tr|Q5T624|Q5T624_HUMAN,tr|H0YF33|H0YF33_HUMAN,tr|E9PRH9|E9PRH9_HUMAN" 5 1627.9152 0.63 38647 24236 3 1627.913068 543.6457 Nuclear autoantigenic sperm protein OS=Homo sapiens OX=9606 GN=NASP PE=1 SV=2 4.33 3749.8 - 546994 - - - -1.2839 - 2.369 0.383 - 175.7 1 2 1 -0.0021 13 0 0 0 1.25E+07 1.99E+07 - - - 5.1479 0.9999 221125_WJC_METTL3_EV_vs_WT_F03.24240.24240.2 4.98E-05 16/24 R.NSILAQVLDQSAR.A "sp|O14737|PDCD5_HUMAN,tr|K7ESJ4|K7ESJ4_HUMAN,tr|K7EQA1|K7EQA1_HUMAN" 3 1413.7576 1.31 38649 24240 2 1413.755299 707.8861 Programmed cell death protein 5 OS=Homo sapiens OX=9606 GN=PDCD5 PE=1 SV=3 5.84 3750.3 - 3.54E+06 - - - -1.6219 - 2.861 0.51 - 1176.2 1 2 0 -0.0023 13 0 0 0 5.56E+07 4.26E+07 - - - 5.505 1 221125_WJC_METTL3_EV_vs_WT_F03.24241.24241.3 3.17E-07 17/72 K.K[136.11]LGGSLADSYLDEGFLLDK[136.11].K "sp|P78371|TCPB_HUMAN,tr|F8VQ14|F8VQ14_HUMAN,tr|F5GWF6|F5GWF6_HUMAN" 3 2056.0699 0.5 38650 24241 3 2056.070063 686.3639 T-complex protein 1 subunit beta OS=Homo sapiens OX=9606 GN=CCT2 PE=1 SV=4 4.23 3750.4 - 2.39E+06 - - - 0.0608 - 3.431 0.574 - 444.5 1 2 0 0.0001 19 0 0 0 3.13E+07 6.21E+07 - - - 7.9684 1 221125_WJC_METTL3_EV_vs_WT_F03.24248.24248.3 0.000575 15/52 R.AQLADSFHLQQFFR.D "sp|Q13813|SPTN1_HUMAN,tr|A0A0D9SF54|A0A0D9SF54_HUMAN,tr|A0A0D9SGF6|A0A0D9SGF6_HUMAN" 3 1706.8529 1.23 38655 24248 3 1706.851256 569.9582 "Spectrin alpha chain, non-erythrocytic 1 OS=Homo sapiens OX=9606 GN=SPTAN1 PE=1 SV=3" 6.79 3751.1 - 3.56E+06 - - - -0.9567 - 3.356 0.481 - 445.2 1 2 0 -0.0016 14 0 0 0 4.70E+07 3.82E+07 - - - 7.1198 0.9999 221125_WJC_METTL3_EV_vs_WT_F03.24251.24251.3 8.07E-10 16/68 K.SK[136.11]AEC[160.03]EILMMVGLPAAGK[136.11].T "sp|Q9BUJ2|HNRL1_HUMAN,tr|M0QYZ0|M0QYZ0_HUMAN,tr|A0A0A0MRA5|A0A0A0MRA5_HUMAN,tr|M0R3F1|M0R3F1_HUMAN,tr|B7Z4B8|B7Z4B8_HUMAN" 5 1919.9854 1.27 38658 24251 3 1919.986111 641.0024 Heterogeneous nuclear ribonucleoprotein U-like protein 1 OS=Homo sapiens OX=9606 GN=HNRNPUL1 PE=1 SV=2 5.86 3751.5 - 1.04E+06 - - - 0.3901 - 3.115 0.558 - 310.3 1 2 1 0.0007 18 0 0 0 2.17E+07 1.70E+07 - - - 7.5903 0.9999 221125_WJC_METTL3_EV_vs_WT_F03.24252.24252.3 7.16E-08 21/76 R.SILGTLTVEQIYQDRDQFAK.L "sp|Q14254|FLOT2_HUMAN,tr|E7EMK3|E7EMK3_HUMAN,tr|J3QLD9|J3QLD9_HUMAN" 3 2324.2012 4.77 38659 24252 3 2324.201026 775.741 Flotillin-2 OS=Homo sapiens OX=9606 GN=FLOT2 PE=1 SV=2 4.56 3751.6 - 974777 - - - -0.0861 - 3.524 0.558 - 331.8 1 2 1 -0.0002 20 0 0 0 7.52E+06 1.58E+06 - - - 7.8169 1 221125_WJC_METTL3_EV_vs_WT_F03.24254.24254.3 1.50E-05 19/44 K.SLLDILTDPSKR.C "sp|Q96RN5|MED15_HUMAN,tr|G3V1P5|G3V1P5_HUMAN" 2 1356.7613 3.9 38661 24254 3 1356.760291 453.261 Mediator of RNA polymerase II transcription subunit 15 OS=Homo sapiens OX=9606 GN=MED15 PE=1 SV=2 5.68 3751.8 - 787805 - - - -0.7289 - 2.924 0.462 - 460.2 1 2 0 -0.001 12 0 0 0 2.57E+07 6.60E+06 - - - 6.6646 1 221125_WJC_METTL3_EV_vs_WT_F03.24255.24255.3 6.06E-09 20/104 K.WSPTGPGTNNPNANLMLASASFDSTVR.L "sp|Q9BZK7|TBL1R_HUMAN,tr|A0A0D9SF63|A0A0D9SF63_HUMAN" 2 2804.3188 3.34 38662 24255 3 2804.309933 935.7802 F-box-like\WD repeat-containing protein TBL1XR1 OS=Homo sapiens OX=9606 GN=TBL1XR1 PE=1 SV=1 5.84 3751.9 - 754490 - - - -3.1591 - 3.651 0.617 - 208.6 1 2 0 -0.0089 27 0 0 0 6.86E+06 2.05E+06 - - - 8.3958 1 221125_WJC_METTL3_EV_vs_WT_F03.24256.24256.2 1.62E-12 19/36 R.YEGILYTIDTENSTVALAK[136.11].V "sp|Q8ND56|LS14A_HUMAN,tr|I3L4Q1|I3L4Q1_HUMAN,tr|A0A140TA76|A0A140TA76_HUMAN,tr|K7EMZ9|K7EMZ9_HUMAN" 4 2108.0769 1.07 38663 24256 2 2108.073944 1055.0457 Protein LSM14 homolog A OS=Homo sapiens OX=9606 GN=LSM14A PE=1 SV=3 4.14 3752.1 - 645034 - - - -1.3866 - 3.622 0.69 - 1015.5 1 2 0 -0.0029 19 0 0 0 7.57E+07 7.05E+07 - - - 7.3006 1 221125_WJC_METTL3_EV_vs_WT_F03.24260.24260.3 4.41E-07 22/108 K.SGDAAIVDMVPGK[136.11]PMC[160.03]VESFSDYPPLGR[166.11].F "sp|P68104|EF1A1_HUMAN,sp|Q5VTE0|EF1A3_HUMAN,tr|A0A7I2V659|A0A7I2V659_HUMAN,tr|A0A087WVQ9|A0A087WVQ9_HUMAN" 4 3012.415 0.17 38665 24260 3 3012.412057 1005.1456 Elongation factor 1-alpha 1 OS=Homo sapiens OX=9606 GN=EEF1A1 PE=1 SV=1 4.23 3752.6 - 1.25E+06 - - - -0.9839 - 3.994 0.663 - 373.8 1 2 0 -0.003 28 0 0 0 1.52E+07 9.04E+07 - - - 9.1169 1 221125_WJC_METTL3_EV_vs_WT_F03.24261.24261.3 6.20E-15 27/96 R.SFPSYYTSHVQEEQIEVEETIEAAK.A sp|P07196|NFL_HUMAN 1 2913.3556 3.31 38666 24261 3 2913.35788 972.1258 Neurofilament light polypeptide OS=Homo sapiens OX=9606 GN=NEFL PE=1 SV=3 4.2 3752.7 - 3.07E+06 - - - 0.7778 - 4.268 0.664 - 482 1 2 0 0.0023 25 0 0 0 2.37E+07 7.15E+06 - - - 9.2809 1 221125_WJC_METTL3_EV_vs_WT_F03.24262.24262.4 1.26E-11 20/126 R.LLQDHPWLLSQNLVVK[136.11]PDQLIK[136.11].R "sp|P53396|ACLY_HUMAN,tr|K7ESG8|K7ESG8_HUMAN" 2 2612.5025 0.65 38667 24262 4 2612.504021 654.1329 ATP-citrate synthase OS=Homo sapiens OX=9606 GN=ACLY PE=1 SV=3 6.75 3752.8 - 2.50E+06 - - - 0.5845 - 3.434 0.666 - 190.2 1 2 0 0.0015 22 0 0 0 1.73E+07 2.65E+07 - - - 5.4261 0.9805 221125_WJC_METTL3_EV_vs_WT_F03.24267.24267.3 0.271 17/56 R.LQAIEHELHELGLLK.D "sp|Q16769|QPCT_HUMAN,tr|B5MCZ9|B5MCZ9_HUMAN,tr|C9JS14|C9JS14_HUMAN" 3 1741.9727 1.48 38672 24267 3 1741.970859 581.6648 Glutaminyl-peptide cyclotransferase OS=Homo sapiens OX=9606 GN=QPCT PE=1 SV=1 5.33 3753.4 - 746797 - - - -1.0396 - 1.774 0.124 - 191.5 1 2 0 -0.0018 15 0 0 0 7.89E+06 5.31E+06 - - - 1.4178 0.894 221125_WJC_METTL3_EV_vs_WT_F03.24269.24269.3 0.183 Nov-56 R.LQAIEHELHELGLLK[136.11].D "sp|Q16769|QPCT_HUMAN,tr|B5MCZ9|B5MCZ9_HUMAN,tr|C9JS14|C9JS14_HUMAN" 3 1749.9869 1.48 38674 24269 3 1749.98605 584.3362 Glutaminyl-peptide cyclotransferase OS=Homo sapiens OX=9606 GN=QPCT PE=1 SV=1 5.33 3753.6 - 584146 - - - -0.4686 - 1.889 0.019 - 121.3 1 2 0 -0.0008 15 0 0 0 7.89E+06 5.31E+06 - - - 0.4113 0.999 221125_WJC_METTL3_EV_vs_WT_F03.24270.24270.4 0.0217 Aug-84 R.LQAIEHELHELGLLK[136.11].D "sp|Q16769|QPCT_HUMAN,tr|B5MCZ9|B5MCZ9_HUMAN,tr|C9JS14|C9JS14_HUMAN" 3 1749.9869 1.64 38675 24270 4 1749.983566 438.504 Glutaminyl-peptide cyclotransferase OS=Homo sapiens OX=9606 GN=QPCT PE=1 SV=1 5.33 3753.8 - 476966 - - - -1.888 - 1.714 0.32 - 48.2 1 2 0 -0.0033 15 0 0 0 3.86E+06 2.35E+06 - - - 2.2032 0.9864 221125_WJC_METTL3_EV_vs_WT_F03.24274.24274.3 0.405 Sep-64 K.ISAPNEFDVMFKLEVPR.L "sp|Q8N884|CGAS_HUMAN,tr|A0A7P0TBQ3|A0A7P0TBQ3_HUMAN" 2 1991.0186 68.69 38676 24274 3 1991.019311 664.6802 Cyclic GMP-AMP synthase OS=Homo sapiens OX=9606 GN=CGAS PE=1 SV=2 4.68 3754.3 - 2.08E+06 - - - 0.34 - 1.773 0.231 - 51.4 1 2 1 0.0007 17 0 0 0 8.71E+07 1.27E+06 - - - 2.562 0.9995 221125_WJC_METTL3_EV_vs_WT_F03.24278.24278.4 0.000925 17/120 R.QFGFIVLTTSAGIMDHEEAR[166.11]R[166.11].K sp|P62244|RS15A_HUMAN 1 2397.2014 1.04 38680 24278 4 2397.200504 600.3076 40S ribosomal protein S15a OS=Homo sapiens OX=9606 GN=RPS15A PE=1 SV=2 5.45 3754.7 - 1.27E+06 - - - -0.3759 - 2.647 0.319 - 205.9 1 2 0 -0.0009 21 0 0 0 1.34E+07 1.29E+07 - - - 2.3242 1 221125_WJC_METTL3_EV_vs_WT_F03.24281.24281.3 5.20E-06 17/52 R.EEQIVQLLNSVQAK.N "sp|Q9H2U1|DHX36_HUMAN,tr|E7EWK3|E7EWK3_HUMAN" 2 1597.8675 1.12 38683 24281 3 1597.869703 533.6298 ATP-dependent DNA\RNA helicase DHX36 OS=Homo sapiens OX=9606 GN=DHX36 PE=1 SV=2 4.53 3755.1 - 1.02E+06 - - - 1.3562 - 2.574 0.49 - 540.1 1 2 0 0.0022 14 0 0 0 1.01E+07 9.08E+06 - - - 6.515 1 221125_WJC_METTL3_EV_vs_WT_F03.24282.24282.2 4.05E-07 15/30 K.EQNIVFNAETYSNLIK[136.11].L "sp|P42704|LPPRC_HUMAN,tr|A0A804HI14|A0A804HI14_HUMAN,tr|A0A804HL40|A0A804HL40_HUMAN,tr|A0A804HKJ0|A0A804HKJ0_HUMAN,tr|A0A804HKR3|A0A804HKR3_HUMAN,tr|A0A804HIN4|A0A804HIN4_HUMAN,tr|A0A804HLG8|A0A804HLG8_HUMAN,tr|A0A804HJA1|A0A804HJA1_HUMAN,tr|A0A804HHY9|A0A804HHY9_HUMAN,tr|A0A804HI40|A0A804HI40_HUMAN,tr|A0A804HJZ1|A0A804HJZ1_HUMAN,tr|A0A804HIQ7|A0A804HIQ7_HUMAN,tr|A0A804HK30|A0A804HK30_HUMAN,tr|A0A804HKI2|A0A804HKI2_HUMAN,tr|A0A804HJI0|A0A804HJI0_HUMAN,tr|A0A804HKX6|A0A804HKX6_HUMAN,tr|A0A804HKK7|A0A804HKK7_HUMAN,tr|A0A804HIG4|A0A804HIG4_HUMAN" 18 1889.9614 0.77 38684 24282 2 1889.962463 945.988 "Leucine-rich PPR motif-containing protein, mitochondrial OS=Homo sapiens OX=9606 GN=LRPPRC PE=1 SV=3" 4.53 3755.2 - 992261 - - - 0.5397 - 2.999 0.602 - 616.7 1 2 0 0.001 16 0 0 0 1.13E+07 1.47E+07 - - - 6.1872 1 221125_WJC_METTL3_EV_vs_WT_F03.24283.24283.2 3.10E-09 14/30 K.EQNIVFNAETYSNLIK.L "sp|P42704|LPPRC_HUMAN,tr|A0A804HI14|A0A804HI14_HUMAN,tr|A0A804HL40|A0A804HL40_HUMAN,tr|A0A804HKJ0|A0A804HKJ0_HUMAN,tr|A0A804HKR3|A0A804HKR3_HUMAN,tr|A0A804HIN4|A0A804HIN4_HUMAN,tr|A0A804HLG8|A0A804HLG8_HUMAN,tr|A0A804HJA1|A0A804HJA1_HUMAN,tr|A0A804HHY9|A0A804HHY9_HUMAN,tr|A0A804HI40|A0A804HI40_HUMAN,tr|A0A804HJZ1|A0A804HJZ1_HUMAN,tr|A0A804HIQ7|A0A804HIQ7_HUMAN,tr|A0A804HK30|A0A804HK30_HUMAN,tr|A0A804HKI2|A0A804HKI2_HUMAN,tr|A0A804HJI0|A0A804HJI0_HUMAN,tr|A0A804HKX6|A0A804HKX6_HUMAN,tr|A0A804HKK7|A0A804HKK7_HUMAN,tr|A0A804HIG4|A0A804HIG4_HUMAN" 18 1881.9472 0.77 38685 24283 2 1881.945928 941.9809 "Leucine-rich PPR motif-containing protein, mitochondrial OS=Homo sapiens OX=9606 GN=LRPPRC PE=1 SV=3" 4.53 3755.3 - 893071 - - - -0.6987 - 2.972 0.642 - 536.5 1 2 0 -0.0013 16 0 0 0 1.13E+07 1.47E+07 - - - 6.4603 1 221125_WJC_METTL3_EV_vs_WT_F03.24284.24284.3 3.78E-08 18/76 K.VVKPLDYEAMQSLQLSIGVR.N sp|Q02413|DSG1_HUMAN 1 2245.214 999 38686 24284 3 2245.211885 749.412 Desmoglein-1 OS=Homo sapiens OX=9606 GN=DSG1 PE=1 SV=2 6.04 3755.4 - 803251 - - - -0.9594 - 3.169 0.447 - 246.7 1 2 0 -0.0022 20 0 0 0 4.08E+06 0.00E+00 - - - 6.3212 1 221125_WJC_METTL3_EV_vs_WT_F03.24287.24287.3 0.000269 17/44 K.SLLDILTDPSK[136.11]R[166.11].C "sp|Q96RN5|MED15_HUMAN,tr|G3V1P5|G3V1P5_HUMAN" 2 1374.7838 3.9 38689 24287 3 1374.781466 459.2685 Mediator of RNA polymerase II transcription subunit 15 OS=Homo sapiens OX=9606 GN=MED15 PE=1 SV=2 5.68 3755.8 - 663323 - - - -1.6614 - 2.77 0.47 - 339.3 1 2 0 -0.0023 12 0 0 0 2.57E+07 6.60E+06 - - - 6.6035 0.9999 221125_WJC_METTL3_EV_vs_WT_F03.24289.24289.3 0.000447 16/56 R.RQELDAFLAQALSPK.L "sp|Q9NZB2|F120A_HUMAN,tr|A0A0C4DG79|A0A0C4DG79_HUMAN" 2 1685.9101 0.88 38691 24289 3 1685.915006 562.9773 Constitutive coactivator of PPAR-gamma-like protein 1 OS=Homo sapiens OX=9606 GN=FAM120A PE=1 SV=2 6.07 3756.1 - 447788 - - - 2.9278 - 3.011 0.538 - 325.5 1 2 0 0.0049 15 0 0 0 1.08E+07 1.24E+07 - - - 7.413 1 221125_WJC_METTL3_EV_vs_WT_F03.24292.24292.2 2.35E-08 15/26 K.NSSYFVEWIPNNVK.T "sp|P04350|TBB4A_HUMAN,sp|Q9BVA1|TBB2B_HUMAN,sp|P07437|TBB5_HUMAN,sp|Q13509|TBB3_HUMAN,sp|Q13885|TBB2A_HUMAN,sp|P68371|TBB4B_HUMAN,sp|Q9BUF5|TBB6_HUMAN,tr|A0A0B4J269|A0A0B4J269_HUMAN,tr|Q5ST81|Q5ST81_HUMAN,tr|Q5JP53|Q5JP53_HUMAN,tr|K7ESM5|K7ESM5_HUMAN" 11 1695.8257 0.71 38692 24292 2 1695.828735 848.9201 Tubulin beta-4A chain OS=Homo sapiens OX=9606 GN=TUBB4A PE=1 SV=2 6 3756.5 - 4.13E+06 - - - 1.8068 - 2.532 0.632 - 510.6 1 2 0 0.0031 14 0 0 0 3.22E+08 4.53E+08 - - - 6.0393 1 221125_WJC_METTL3_EV_vs_WT_F03.24296.24296.3 1.44E-10 21/80 R.LVSSPC[160.03]C[160.03]IVTSTYGWTANMER.L sp|P08238|HS90B_HUMAN 1 2431.097 0.69 38696 24296 3 2431.091993 811.373 Heat shock protein HSP 90-beta OS=Homo sapiens OX=9606 GN=HSP90AB1 PE=1 SV=4 5.99 3756.8 - 2.36E+06 - - - -2.0752 - 3.536 0.622 - 439.5 1 2 0 -0.005 21 0 0 0 2.55E+07 3.68E+07 - - - 8.5013 0.9998 221125_WJC_METTL3_EV_vs_WT_F03.24297.24297.3 0.00815 13/52 K.NSSYFVEWIPNNVK[136.11].T "sp|P04350|TBB4A_HUMAN,sp|Q9BVA1|TBB2B_HUMAN,sp|P07437|TBB5_HUMAN,sp|Q13509|TBB3_HUMAN,sp|Q13885|TBB2A_HUMAN,sp|P68371|TBB4B_HUMAN,sp|Q9BUF5|TBB6_HUMAN,tr|A0A0B4J269|A0A0B4J269_HUMAN,tr|Q5ST81|Q5ST81_HUMAN,tr|Q5JP53|Q5JP53_HUMAN,tr|K7ESM5|K7ESM5_HUMAN" 11 1703.8399 0.74 38697 24297 3 1703.842346 568.9539 Tubulin beta-4A chain OS=Homo sapiens OX=9606 GN=TUBB4A PE=1 SV=2 6 3756.9 - 2.05E+06 - - - 1.4526 - 2.079 0.387 - 165 1 2 0 0.0025 14 0 0 0 7.51E+07 1.02E+08 - - - 4.799 1 221125_WJC_METTL3_EV_vs_WT_F03.24298.24298.3 3.60E-06 15/60 K.EQNIVFNAETYSNLIK[136.11].L "sp|P42704|LPPRC_HUMAN,tr|A0A804HI14|A0A804HI14_HUMAN,tr|A0A804HL40|A0A804HL40_HUMAN,tr|A0A804HKJ0|A0A804HKJ0_HUMAN,tr|A0A804HKR3|A0A804HKR3_HUMAN,tr|A0A804HIN4|A0A804HIN4_HUMAN,tr|A0A804HLG8|A0A804HLG8_HUMAN,tr|A0A804HJA1|A0A804HJA1_HUMAN,tr|A0A804HHY9|A0A804HHY9_HUMAN,tr|A0A804HI40|A0A804HI40_HUMAN,tr|A0A804HJZ1|A0A804HJZ1_HUMAN,tr|A0A804HIQ7|A0A804HIQ7_HUMAN,tr|A0A804HK30|A0A804HK30_HUMAN,tr|A0A804HKI2|A0A804HKI2_HUMAN,tr|A0A804HJI0|A0A804HJI0_HUMAN,tr|A0A804HKX6|A0A804HKX6_HUMAN,tr|A0A804HKK7|A0A804HKK7_HUMAN,tr|A0A804HIG4|A0A804HIG4_HUMAN" 18 1889.9614 0.83 38698 24298 3 1889.963233 630.9944 "Leucine-rich PPR motif-containing protein, mitochondrial OS=Homo sapiens OX=9606 GN=LRPPRC PE=1 SV=3" 4.53 3756.9 - 1.90E+06 - - - 0.9471 - 2.863 0.519 - 330.3 1 2 0 0.0018 16 0 0 0 1.34E+07 1.61E+07 - - - 7.0248 1 221125_WJC_METTL3_EV_vs_WT_F03.24299.24299.3 7.24E-08 20/60 K.EQNIVFNAETYSNLIK.L "sp|P42704|LPPRC_HUMAN,tr|A0A804HI14|A0A804HI14_HUMAN,tr|A0A804HL40|A0A804HL40_HUMAN,tr|A0A804HKJ0|A0A804HKJ0_HUMAN,tr|A0A804HKR3|A0A804HKR3_HUMAN,tr|A0A804HIN4|A0A804HIN4_HUMAN,tr|A0A804HLG8|A0A804HLG8_HUMAN,tr|A0A804HJA1|A0A804HJA1_HUMAN,tr|A0A804HHY9|A0A804HHY9_HUMAN,tr|A0A804HI40|A0A804HI40_HUMAN,tr|A0A804HJZ1|A0A804HJZ1_HUMAN,tr|A0A804HIQ7|A0A804HIQ7_HUMAN,tr|A0A804HK30|A0A804HK30_HUMAN,tr|A0A804HKI2|A0A804HKI2_HUMAN,tr|A0A804HJI0|A0A804HJI0_HUMAN,tr|A0A804HKX6|A0A804HKX6_HUMAN,tr|A0A804HKK7|A0A804HKK7_HUMAN,tr|A0A804HIG4|A0A804HIG4_HUMAN" 18 1881.9472 0.85 38699 24299 3 1881.944628 628.323 "Leucine-rich PPR motif-containing protein, mitochondrial OS=Homo sapiens OX=9606 GN=LRPPRC PE=1 SV=3" 4.53 3757.1 - 1.54E+06 - - - -1.3895 - 3.318 0.583 - 619.1 1 2 0 -0.0026 16 0 0 0 1.38E+07 1.62E+07 - - - 8.1166 1 221125_WJC_METTL3_EV_vs_WT_F03.24300.24300.3 1.07E-13 26/100 R.LILPVGPAGGNQMLEQYDKLQDGSIK.M "sp|P22061|PIMT_HUMAN,tr|F6S8N6|F6S8N6_HUMAN,tr|A0A3F2YNX8|A0A3F2YNX8_HUMAN,tr|A0A0A0MRJ6|A0A0A0MRJ6_HUMAN" 4 2783.4528 1.3 38700 24300 3 2783.455324 928.8249 Protein-L-isoaspartate(D-aspartate) O-methyltransferase OS=Homo sapiens OX=9606 GN=PCMT1 PE=1 SV=4 4.56 3757.2 - 1.50E+06 - - - 0.919 - 4.623 0.664 - 540.3 1 2 1 0.0026 26 0 0 0 1.99E+07 1.53E+07 - - - 9.4646 1 221125_WJC_METTL3_EV_vs_WT_F03.24301.24301.3 2.12E-09 28/56 R.RLDLFQEHMFEVLER.A "sp|Q86U86|PB1_HUMAN,tr|H0Y5B5|H0Y5B5_HUMAN,tr|E7EVG2|E7EVG2_HUMAN" 3 1960.9829 3.34 38701 24301 3 1960.986824 654.6682 Protein polybromo-1 OS=Homo sapiens OX=9606 GN=PBRM1 PE=1 SV=1 4.83 3757.3 - 1.34E+06 - - - 1.9924 - 4.599 0.617 - 1487 1 2 0 0.0039 15 0 0 0 1.86E+07 5.59E+06 - - - 9.3993 0.9693 221125_WJC_METTL3_EV_vs_WT_F03.24302.24302.3 0.113 Sep-88 R.VTGAALIPPPGGTSLTSLGQAAQ.- sp|Q9BU61|NDUF3_HUMAN 1 2106.1321 - 38702 24302 3 2106.138254 703.0513 NADH dehydrogenase [ubiquinone] 1 alpha subcomplex assembly factor 3 OS=Homo sapiens OX=9606 GN=NDUFAF3 PE=1 SV=1 5.49 3757.4 - 1.29E+06 - - - 2.9295 - 1.895 0.167 - 59.9 1 2 0 0.0062 23 0 0 0 - - - - - 1.8997 1 221125_WJC_METTL3_EV_vs_WT_F03.24303.24303.3 8.34E-06 15/52 K.NSSYFVEWIPNNVK.T "sp|P04350|TBB4A_HUMAN,sp|Q9BVA1|TBB2B_HUMAN,sp|P07437|TBB5_HUMAN,sp|Q13509|TBB3_HUMAN,sp|Q13885|TBB2A_HUMAN,sp|P68371|TBB4B_HUMAN,sp|Q9BUF5|TBB6_HUMAN,tr|A0A0B4J269|A0A0B4J269_HUMAN,tr|Q5ST81|Q5ST81_HUMAN,tr|Q5JP53|Q5JP53_HUMAN,tr|K7ESM5|K7ESM5_HUMAN" 11 1695.8257 0.68 38703 24303 3 1695.82757 566.2825 Tubulin beta-4A chain OS=Homo sapiens OX=9606 GN=TUBB4A PE=1 SV=2 6 3757.5 - 1.24E+06 - - - 1.1198 - 2.25 0.542 - 212 1 2 0 0.0019 14 0 0 0 7.57E+07 1.11E+08 - - - 6.7373 1 221125_WJC_METTL3_EV_vs_WT_F03.24307.24307.4 0.0137 19/84 R.R[166.11]LDLFQEHMFEVLER[166.11].A "sp|Q86U86|PB1_HUMAN,tr|H0Y5B5|H0Y5B5_HUMAN,tr|E7EVG2|E7EVG2_HUMAN" 3 1980.9995 1.22 38707 24307 4 1980.999745 496.2571 Protein polybromo-1 OS=Homo sapiens OX=9606 GN=PBRM1 PE=1 SV=1 4.83 3758 - 444748 - - - 0.1454 - 3.977 0.527 - 372.4 1 2 0 0.0003 15 0 0 0 5.26E+06 4.30E+06 - - - 4.3069 0.9997 221125_WJC_METTL3_EV_vs_WT_F03.24308.24308.2 0.000239 14/44 R.VTGAALIPPPGGTSLTSLGQAAQ.- sp|Q9BU61|NDUF3_HUMAN 1 2106.1321 - 38708 24308 2 2106.134946 1054.0733 NADH dehydrogenase [ubiquinone] 1 alpha subcomplex assembly factor 3 OS=Homo sapiens OX=9606 GN=NDUFAF3 PE=1 SV=1 5.49 3758.1 - 355885 - - - 1.3589 - 2.252 0.425 - 291 1 2 0 0.0029 23 0 0 0 - - - - - 4.175 0.9934 221125_WJC_METTL3_EV_vs_WT_F03.24312.24312.2 3.00E-07 Dec-34 K.QTQIFTTYSDNQPGVLIQ.V "sp|P0DMV8|HS71A_HUMAN,sp|P34931|HS71L_HUMAN,sp|P0DMV9|HS71B_HUMAN,tr|Q53FA3|Q53FA3_HUMAN,tr|V9GZ37|V9GZ37_HUMAN,tr|A0A0G2JIW1|A0A0G2JIW1_HUMAN" 6 2052.0164 - 38710 24312 2 2052.015136 1027.0155 Heat shock 70 kDa protein 1A OS=Homo sapiens OX=9606 GN=HSPA1A PE=1 SV=1 3.8 3758.7 - 7.65E+06 - - - -0.6087 - 2.225 0.556 - 263.4 1 1 0 -0.0012 18 0 0 0 - - - - - 5.1135 1 221125_WJC_METTL3_EV_vs_WT_F03.24313.24313.3 2.45E-13 26/108 F.GLSVPNVHGALAPLAIPSAAAAAAAAGR.L "sp|P26599|PTBP1_HUMAN,tr|A0A0U1RRM4|A0A0U1RRM4_HUMAN,tr|A6NLN1|A6NLN1_HUMAN,tr|A0A087WU68|A0A087WU68_HUMAN,tr|A0A7I2V621|A0A7I2V621_HUMAN,tr|A0A087WTS6|A0A087WTS6_HUMAN,tr|K7EK45|K7EK45_HUMAN" 7 2493.3816 0.84 38711 24313 3 2493.383779 832.1345 Polypyrimidine tract-binding protein 1 OS=Homo sapiens OX=9606 GN=PTBP1 PE=1 SV=1 9.76 3758.7 - 5.02E+06 - - - 0.8775 - 4.682 0.594 - 301.5 1 1 0 0.0022 28 0 0 0 3.74E+07 4.47E+07 - - - 8.7135 1 221125_WJC_METTL3_EV_vs_WT_F03.24314.24314.3 3.29E-07 15/88 R.ELSLAAAQNGFVDSAAAHMGAFK.L sp|O95409|ZIC2_HUMAN 1 2305.1161 2.52 38712 24314 3 2305.11053 769.3793 Zinc finger protein ZIC 2 OS=Homo sapiens OX=9606 GN=ZIC2 PE=1 SV=2 5.32 3758.8 - 1.15E+07 - - - -2.4233 - 3.294 0.566 - 186.1 1 2 0 -0.0056 23 0 0 0 4.81E+07 1.90E+07 - - - 7.6454 1 221125_WJC_METTL3_EV_vs_WT_F03.24317.24317.3 4.88E-09 15/64 R.NNFEGEVTKENLLDFIK.H "sp|P07237|PDIA1_HUMAN,tr|A0A7P0TA97|A0A7P0TA97_HUMAN,tr|A0A7P0T8C0|A0A7P0T8C0_HUMAN,tr|H7BZ94|H7BZ94_HUMAN,tr|A0A7P0TA71|A0A7P0TA71_HUMAN,tr|I3L4M2|I3L4M2_HUMAN,tr|A0A7P0T9D6|A0A7P0T9D6_HUMAN,tr|A0A7P0T9K9|A0A7P0T9K9_HUMAN,tr|H0Y3Z3|H0Y3Z3_HUMAN,tr|A0A7P0Z4S2|A0A7P0Z4S2_HUMAN,tr|A0A7P0TA35|A0A7P0TA35_HUMAN,tr|I3L514|I3L514_HUMAN,tr|A0A7P0TB26|A0A7P0TB26_HUMAN,tr|A0A7P0T9U6|A0A7P0T9U6_HUMAN,tr|I3L0S0|I3L0S0_HUMAN,tr|I3L3P5|I3L3P5_HUMAN,tr|A0A7P0T8J3|A0A7P0T8J3_HUMAN,tr|A0A7P0Z4J0|A0A7P0Z4J0_HUMAN,tr|A0A7P0T8X1|A0A7P0T8X1_HUMAN" 19 2009.0106 1.34 38715 24317 3 2009.003402 670.6775 Protein disulfide-isomerase OS=Homo sapiens OX=9606 GN=P4HB PE=1 SV=3 4.41 3758.9 - 3.45E+06 - - - -3.5689 - 3.559 0.628 - 307.1 1 2 1 -0.0072 17 0 0 0 4.04E+07 3.03E+07 - - - 8.7467 1 221125_WJC_METTL3_EV_vs_WT_F03.24319.24319.3 2.89E-07 15/56 R.DYLHLPPEIVPATLR.R "sp|P46783|RS10_HUMAN,tr|A0A2R8Y6L3|A0A2R8Y6L3_HUMAN,tr|F6U211|F6U211_HUMAN,tr|A0A1W2PQS6|A0A1W2PQS6_HUMAN,tr|A0A2R8YFH6|A0A2R8YFH6_HUMAN,tr|A0A2R8Y7H1|A0A2R8Y7H1_HUMAN,tr|S4R435|S4R435_HUMAN" 7 1732.9512 1.37 38717 24319 3 1732.949326 578.6577 40S ribosomal protein S10 OS=Homo sapiens OX=9606 GN=RPS10 PE=1 SV=1 5.32 3759 - 2.38E+06 - - - -1.0849 - 2.915 0.555 - 179 1 2 0 -0.0019 15 0 0 0 2.52E+08 1.84E+08 - - - 7.5189 1 221125_WJC_METTL3_EV_vs_WT_F03.24320.24320.3 1.27E-06 20/84 K.AETLMTVTDPVHDIAFAPNLGR[166.11].S "sp|Q96EE3|SEH1_HUMAN,tr|K7ELV2|K7ELV2_HUMAN" 2 2377.1976 1.52 38718 24320 3 2377.197784 793.4065 Nucleoporin SEH1 OS=Homo sapiens OX=9606 GN=SEH1L PE=1 SV=3 4.54 3759.2 - 1.54E+06 - - - 0.098 - 4.073 0.565 - 633 1 2 0 0.0002 22 0 0 0 1.46E+07 9.63E+06 - - - 8.1687 1 221125_WJC_METTL3_EV_vs_WT_F03.24323.24323.4 6.16E-09 20/84 R.RLDLFQEHMFEVLER.A "sp|Q86U86|PB1_HUMAN,tr|H0Y5B5|H0Y5B5_HUMAN,tr|E7EVG2|E7EVG2_HUMAN" 3 1960.9829 1.22 38721 24323 4 1960.983793 491.253 Protein polybromo-1 OS=Homo sapiens OX=9606 GN=PBRM1 PE=1 SV=1 4.83 3759.5 - 932835 - - - 0.4467 - 4.305 0.64 - 457.6 1 2 0 0.0009 15 0 0 0 5.26E+06 4.30E+06 - - - 5.3186 0.9999 221125_WJC_METTL3_EV_vs_WT_F03.24324.24324.3 0.000189 14/48 K.VSDILHSIFSSYK.E "sp|O00410|IPO5_HUMAN,tr|H0Y8C6|H0Y8C6_HUMAN" 2 1494.7718 0.81 38722 24324 3 1494.771909 499.2646 Importin-5 OS=Homo sapiens OX=9606 GN=IPO5 PE=1 SV=4 6.71 3759.6 - 922909 - - - 0.0428 - 2.627 0.385 - 310.9 1 2 0 0.0001 13 0 0 0 9.18E+06 1.13E+07 - - - 5.451 1 221125_WJC_METTL3_EV_vs_WT_F03.24326.24326.3 5.54E-07 17/48 K.VSDILHSIFSSYK[136.11].E "sp|O00410|IPO5_HUMAN,tr|H0Y8C6|H0Y8C6_HUMAN" 2 1502.786 0.81 38724 24326 3 1502.786501 501.936 Importin-5 OS=Homo sapiens OX=9606 GN=IPO5 PE=1 SV=4 6.71 3759.8 - 778601 - - - 0.3034 - 3.347 0.377 - 494.4 1 2 0 0.0005 13 0 0 0 9.18E+06 1.13E+07 - - - 6.0185 0.9998 221125_WJC_METTL3_EV_vs_WT_F03.24331.24331.2 0.000126 22-Jul R.LFPPQWIC[160.03]C[160.03]DIR[166.11].Y sp|Q86U44|MTA70_HUMAN 1 1613.7722 0.01 38727 24331 2 1613.771912 807.8934 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 5.82 3760.4 - 5.50E+06 - - - -0.1847 - 1.705 0.509 - 111.9 1 2 0 -0.0003 12 0 0 0 7.11E+05 7.66E+07 - - - 4.2043 0.9999 221125_WJC_METTL3_EV_vs_WT_F03.24336.24336.3 2.22E-09 17/76 K.EAHQLFLEPEVLDPESVELK.W "sp|P39748|FEN1_HUMAN,tr|I3L3E9|I3L3E9_HUMAN" 2 2321.1791 0.67 38732 24336 3 2321.187819 774.7336 Flap endonuclease 1 OS=Homo sapiens OX=9606 GN=FEN1 PE=1 SV=1 4.14 3760.7 - 2.23E+06 - - - 3.7589 - 3.224 0.598 - 288.6 1 2 0 0.0087 20 0 0 0 3.90E+07 5.80E+07 - - - 8.0447 0.9984 221125_WJC_METTL3_EV_vs_WT_F03.24337.24337.3 4.57E-08 19/64 L.QLVEPFGVISNHLILNK.L "sp|P43243|MATR3_HUMAN,tr|D6RE02|D6RE02_HUMAN,tr|B3KM87|B3KM87_HUMAN,tr|A8MXP9|A8MXP9_HUMAN,tr|D6R991|D6R991_HUMAN,tr|D6RBK5|D6RBK5_HUMAN,tr|A0A0R4J2E8|A0A0R4J2E8_HUMAN,tr|D6RIA2|D6RIA2_HUMAN,tr|H0Y8T4|H0Y8T4_HUMAN,tr|D6REM6|D6REM6_HUMAN,tr|D6RBI2|D6RBI2_HUMAN" 11 1920.0833 1.61 38733 24337 3 1920.083666 641.035 Matrin-3 OS=Homo sapiens OX=9606 GN=MATR3 PE=1 SV=2 6.75 3760.8 - 1.90E+06 - - - 0.1995 - 3.481 0.524 - 529.4 1 1 0 0.0004 17 0 0 0 4.06E+07 2.52E+07 - - - 7.5331 0.9803 221125_WJC_METTL3_EV_vs_WT_F03.24338.24338.2 0.0202 14-Oct K.DIGFIKLD.- "sp|P62273|RS29_HUMAN,tr|A0A087WTT6|A0A087WTT6_HUMAN" 2 919.5015 1.11 38734 24338 2 919.500135 460.758 40S ribosomal protein S29 OS=Homo sapiens OX=9606 GN=RPS29 PE=1 SV=2 4.54 3760.9 - 1.79E+06 - - - -1.4671 - 1.421 0.288 - 179.6 1 2 1 -0.0013 8 0 0 0 4.01E+07 3.61E+07 - - - 2.2274 0.9705 221125_WJC_METTL3_EV_vs_WT_F03.24339.24339.2 0.0644 14-Aug K.DIGFIK[136.11]LD.- "sp|P62273|RS29_HUMAN,tr|A0A087WTT6|A0A087WTT6_HUMAN" 2 927.5157 1.11 38735 24339 2 927.514601 464.7651 40S ribosomal protein S29 OS=Homo sapiens OX=9606 GN=RPS29 PE=1 SV=2 4.54 3761 - 1.66E+06 - - - -1.1676 - 1.37 0.239 - 113.5 1 2 1 -0.0011 8 0 0 0 4.00E+07 3.61E+07 - - - 1.7554 0.9999 221125_WJC_METTL3_EV_vs_WT_F03.24346.24346.3 0.00271 16/40 R.EAILEYILHQK[136.11].K "sp|Q9Y314|NOSIP_HUMAN,tr|A0A075B797|A0A075B797_HUMAN,tr|M0QX85|M0QX85_HUMAN,tr|M0R1K2|M0R1K2_HUMAN,tr|M0R3B2|M0R3B2_HUMAN,tr|A0A075B6F9|A0A075B6F9_HUMAN" 6 1363.7591 0.74 38742 24346 3 1363.757123 455.5936 Nitric oxide synthase-interacting protein OS=Homo sapiens OX=9606 GN=NOSIP PE=1 SV=1 5.4 3761.8 - 662537 - - - -1.4511 - 2.452 0.408 - 607 1 2 0 -0.002 11 0 0 0 8.59E+06 1.16E+07 - - - 5.6362 0.8362 221125_WJC_METTL3_EV_vs_WT_F03.24347.24347.3 0.254 Sep-48 K.TADK[136.11]LQEFLQTLR[166.11].E "sp|Q9NVI1|FANCI_HUMAN,tr|F8W7R3|F8W7R3_HUMAN,tr|H3BS60|H3BS60_HUMAN,tr|A0A6Q8PGF4|A0A6Q8PGF4_HUMAN,tr|H3BMG4|H3BMG4_HUMAN,tr|A0A6Q8PH09|A0A6Q8PH09_HUMAN,tr|H3BQE2|H3BQE2_HUMAN,tr|H3BT54|H3BT54_HUMAN" 8 1579.8689 0.3 38743 24347 3 1579.872904 527.6302 Fanconi anemia group I protein OS=Homo sapiens OX=9606 GN=FANCI PE=1 SV=4 5.74 3762 - 405618 - - - 2.5489 - 1.709 0.141 - 76 1 2 1 0.004 13 0 0 0 5.90E+05 1.95E+06 - - - 1.5639 1 221125_WJC_METTL3_EV_vs_WT_F03.24352.24352.3 2.27E-11 20/76 K.EAHQLFLEPEVLDPESVELK[136.11].W "sp|P39748|FEN1_HUMAN,tr|I3L3E9|I3L3E9_HUMAN" 2 2329.1933 0.67 38746 24352 3 2329.193336 777.405 Flap endonuclease 1 OS=Homo sapiens OX=9606 GN=FEN1 PE=1 SV=1 4.14 3762.5 - 1.03E+07 - - - 0.018 - 3.626 0.644 - 422.6 1 2 0 0 20 0 0 0 3.90E+07 5.80E+07 - - - 8.845 1 221125_WJC_METTL3_EV_vs_WT_F03.24355.24355.3 1.41E-10 23/80 K.DHVSLGDYEIHDGMNLELYYQ.- sp|Q9BZL1|UBL5_HUMAN 1 2510.106 - 38749 24355 3 2510.110379 837.7093 Ubiquitin-like protein 5 OS=Homo sapiens OX=9606 GN=UBL5 PE=1 SV=1 4.1 3762.7 - 2.75E+06 - - - 1.7426 - 3.992 0.715 - 520.1 1 2 0 0.0044 21 0 0 0 - - - - - 9.8291 1 221125_WJC_METTL3_EV_vs_WT_F03.24359.24359.2 5.77E-13 18/32 K.SQETEC[160.03]TYFSTPLLLGK.K "sp|P40926|MDHM_HUMAN,tr|G3XAL0|G3XAL0_HUMAN" 2 1972.9452 2.02 38753 24359 2 1972.950765 987.4799 "Malate dehydrogenase, mitochondrial OS=Homo sapiens OX=9606 GN=MDH2 PE=1 SV=3" 4.53 3763.1 - 1.27E+06 - - - 2.8232 - 3.491 0.672 - 1008.3 1 2 0 0.0056 17 0 0 0 1.35E+07 6.66E+06 - - - 7.0763 1 221125_WJC_METTL3_EV_vs_WT_F03.24360.24360.3 2.38E-06 21/64 R.SYTGLAPGYTYQFPEFR.V sp|O43347|MSI1H_HUMAN 1 1995.9367 1.75 38754 24360 3 1995.93663 666.3195 RNA-binding protein Musashi homolog 1 OS=Homo sapiens OX=9606 GN=MSI1 PE=1 SV=1 5.72 3763.2 - 1.02E+06 - - - -0.0245 - 2.772 0.529 - 364.1 1 2 0 0 17 0 0 0 2.53E+07 1.44E+07 - - - 7.0136 1 221125_WJC_METTL3_EV_vs_WT_F03.24361.24361.2 1.91E-13 14/32 K.SQETEC[160.03]TYFSTPLLLGK[136.11].K "sp|P40926|MDHM_HUMAN,tr|G3XAL0|G3XAL0_HUMAN" 2 1980.9594 2.02 38755 24361 2 1980.958611 991.487 "Malate dehydrogenase, mitochondrial OS=Homo sapiens OX=9606 GN=MDH2 PE=1 SV=3" 4.53 3763.4 - 826372 - - - -0.3958 - 3.157 0.666 - 614.8 1 2 0 -0.0008 17 0 0 0 1.35E+07 6.66E+06 - - - 6.7862 0.9999 221125_WJC_METTL3_EV_vs_WT_F03.24365.24365.3 0.00437 18/52 R.GIEKPPFELPDFIK.R "sp|Q13435|SF3B2_HUMAN,tr|E9PPJ0|E9PPJ0_HUMAN" 2 1628.8814 1.31 38758 24365 3 1628.877377 543.9677 Splicing factor 3B subunit 2 OS=Homo sapiens OX=9606 GN=SF3B2 PE=1 SV=2 4.68 3763.9 - 3.10E+06 - - - -2.4667 - 3.066 0.433 - 327 1 2 0 -0.004 14 0 0 0 3.82E+07 2.91E+07 - - - 6.3438 0.9999 221125_WJC_METTL3_EV_vs_WT_F03.24371.24371.3 4.69E-07 19/80 K.APSHVPFLLIGGGTAAFAAAR[166.11].S "sp|O95831|AIFM1_HUMAN,tr|A0A6Q8PFW2|A0A6Q8PFW2_HUMAN,tr|A0A6Q8PFA7|A0A6Q8PFA7_HUMAN,tr|A0A6Q8PHJ9|A0A6Q8PHJ9_HUMAN,tr|A0A6Q8PFS4|A0A6Q8PFS4_HUMAN,tr|A0A7I2PK44|A0A7I2PK44_HUMAN,tr|A0A6Q8PF87|A0A6Q8PF87_HUMAN,tr|A0A6Q8PG15|A0A6Q8PG15_HUMAN,tr|A0A6Q8PFE1|A0A6Q8PFE1_HUMAN,tr|A0A7I2RLJ8|A0A7I2RLJ8_HUMAN,tr|A0A6Q8PFQ8|A0A6Q8PFQ8_HUMAN,tr|A0A6Q8PHC0|A0A6Q8PHC0_HUMAN,tr|A0A6Q8PFM5|A0A6Q8PFM5_HUMAN" 13 2033.1086 0.51 38763 24371 3 2033.115292 678.7101 "Apoptosis-inducing factor 1, mitochondrial OS=Homo sapiens OX=9606 GN=AIFM1 PE=1 SV=1" 9.8 3764.3 - 2.46E+06 - - - 3.2915 - 3.54 0.517 - 374.9 1 2 0 0.0067 21 0 0 0 1.13E+07 2.21E+07 - - - 7.3329 0.9938 221125_WJC_METTL3_EV_vs_WT_F03.24374.24374.3 0.000179 15/64 L.QLVEPFGVISNHLILNK[136.11].L "sp|P43243|MATR3_HUMAN,tr|D6RE02|D6RE02_HUMAN,tr|B3KM87|B3KM87_HUMAN,tr|A8MXP9|A8MXP9_HUMAN,tr|D6R991|D6R991_HUMAN,tr|D6RBK5|D6RBK5_HUMAN,tr|A0A0R4J2E8|A0A0R4J2E8_HUMAN,tr|D6RIA2|D6RIA2_HUMAN,tr|H0Y8T4|H0Y8T4_HUMAN,tr|D6REM6|D6REM6_HUMAN,tr|D6RBI2|D6RBI2_HUMAN" 11 1928.0975 1.62 38766 24374 3 1928.098483 643.7064 Matrin-3 OS=Homo sapiens OX=9606 GN=MATR3 PE=1 SV=2 6.75 3764.5 - 2.12E+06 - - - 0.5186 - 2.97 0.397 - 302.8 1 1 0 0.001 17 0 0 0 3.72E+07 2.30E+07 - - - 5.7159 0.9965 221125_WJC_METTL3_EV_vs_WT_F03.24376.24376.3 5.72E-06 21/92 K.SHLSTAGGLAVPSLPTAGPYYSPY.A sp|Q9H7S9|ZN703_HUMAN 1 2405.1903 - 38768 24376 3 2405.194118 802.7374 Zinc finger protein 703 OS=Homo sapiens OX=9606 GN=ZNF703 PE=1 SV=1 6.46 3764.8 - 1.54E+06 - - - 1.5762 - 3.268 0.505 - 283.4 1 1 0 0.0038 24 0 0 0 - - - - - 6.9196 0.9999 221125_WJC_METTL3_EV_vs_WT_F03.24377.24377.2 3.46E-06 28-Nov R.DYLHLPPEIVPATLR.R "sp|P46783|RS10_HUMAN,tr|A0A2R8Y6L3|A0A2R8Y6L3_HUMAN,tr|F6U211|F6U211_HUMAN,tr|A0A1W2PQS6|A0A1W2PQS6_HUMAN,tr|A0A2R8YFH6|A0A2R8YFH6_HUMAN,tr|A0A2R8Y7H1|A0A2R8Y7H1_HUMAN,tr|S4R435|S4R435_HUMAN" 7 1732.9512 1.78 38769 24377 2 1732.95054 867.4829 40S ribosomal protein S10 OS=Homo sapiens OX=9606 GN=RPS10 PE=1 SV=1 5.32 3764.9 - 1.43E+06 - - - -0.3843 - 2.136 0.51 - 130 1 2 0 -0.0007 15 0 0 0 1.64E+07 9.21E+06 - - - 4.6735 0.9923 221125_WJC_METTL3_EV_vs_WT_F03.24378.24378.2 0.0035 13/26 V.DLEIESLLNQQSTK[136.11].E "sp|Q86U44|MTA70_HUMAN,tr|F5H6D8|F5H6D8_HUMAN,tr|H0YFV6|H0YFV6_HUMAN,tr|B4DTN4|B4DTN4_HUMAN" 4 1624.8399 0.04 38770 24378 2 1624.83908 813.4272 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 4.14 3765 - 1.35E+06 - - - -0.5237 - 2.595 0.454 - 568.2 1 1 0 -0.0009 14 0 0 0 4.30E+05 1.02E+07 - - - 4.787 0.9969 221125_WJC_METTL3_EV_vs_WT_F03.24379.24379.3 4.41E-07 15/64 F.AQFGSDLDAATQQLLSR.G sp|P25705|ATPA_HUMAN 1 1819.9064 1.87 38771 24379 3 1819.908968 607.6428 "ATP synthase subunit alpha, mitochondrial OS=Homo sapiens OX=9606 GN=ATP5F1A PE=1 SV=1" 4.21 3765.1 - 1.33E+06 - - - 1.3885 - 2.851 0.515 - 307.1 1 1 0 0.0025 17 0 0 0 1.50E+07 8.04E+06 - - - 6.9278 0.9999 221125_WJC_METTL3_EV_vs_WT_F03.24380.24380.3 9.00E-05 14/40 R.EAILEYILHQK.K "sp|Q9Y314|NOSIP_HUMAN,tr|A0A075B797|A0A075B797_HUMAN,tr|M0QX85|M0QX85_HUMAN,tr|M0R1K2|M0R1K2_HUMAN,tr|M0R3B2|M0R3B2_HUMAN,tr|A0A075B6F9|A0A075B6F9_HUMAN" 6 1355.7449 0.49 38772 24380 3 1355.743326 452.9222 Nitric oxide synthase-interacting protein OS=Homo sapiens OX=9606 GN=NOSIP PE=1 SV=1 5.4 3765.2 - 986496 - - - -1.1625 - 2.303 0.421 - 377.2 1 2 0 -0.0016 11 0 0 0 5.69E+06 1.16E+07 - - - 5.6032 0.9992 221125_WJC_METTL3_EV_vs_WT_F03.24382.24382.2 1.17E-07 13/28 R.DYLHLPPEIVPATLR[166.11].R "sp|P46783|RS10_HUMAN,tr|A0A2R8Y6L3|A0A2R8Y6L3_HUMAN,tr|F6U211|F6U211_HUMAN,tr|A0A1W2PQS6|A0A1W2PQS6_HUMAN,tr|A0A2R8YFH6|A0A2R8YFH6_HUMAN,tr|A0A2R8Y7H1|A0A2R8Y7H1_HUMAN,tr|S4R435|S4R435_HUMAN" 7 1742.9595 1.75 38774 24382 2 1742.964147 872.487 40S ribosomal protein S10 OS=Homo sapiens OX=9606 GN=RPS10 PE=1 SV=1 5.32 3765.5 - 834474 - - - 2.6799 - 2.241 0.404 - 245.6 1 2 0 0.0047 15 0 0 0 1.61E+07 9.21E+06 - - - 4.0073 0.9998 221125_WJC_METTL3_EV_vs_WT_F03.24390.24390.2 7.37E-07 26-Nov K.NSSYFVEWIPNNVK[136.11].T "sp|P04350|TBB4A_HUMAN,sp|Q9BVA1|TBB2B_HUMAN,sp|P07437|TBB5_HUMAN,sp|Q13509|TBB3_HUMAN,sp|Q13885|TBB2A_HUMAN,sp|P68371|TBB4B_HUMAN,sp|Q9BUF5|TBB6_HUMAN,tr|A0A0B4J269|A0A0B4J269_HUMAN,tr|Q5ST81|Q5ST81_HUMAN,tr|Q5JP53|Q5JP53_HUMAN,tr|K7ESM5|K7ESM5_HUMAN" 11 1703.8399 0.71 38780 24390 2 1703.836678 852.9272 Tubulin beta-4A chain OS=Homo sapiens OX=9606 GN=TUBB4A PE=1 SV=2 6 3766.1 - 4.87E+06 - - - -1.874 - 2.058 0.595 - 237.9 1 2 0 -0.0032 14 0 0 0 3.22E+08 4.53E+08 - - - 5.2458 1 221125_WJC_METTL3_EV_vs_WT_F03.24394.24394.3 1.74E-07 14/44 R.LFPPQWIC[160.03]C[160.03]DIR[166.11].Y sp|Q86U44|MTA70_HUMAN 1 1613.7722 0.001 38784 24394 3 1613.769224 538.9313 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 5.82 3766.4 - 2.05E+06 - - - -1.8503 - 2.423 0.554 - 243.5 1 2 0 -0.003 12 0 0 0 0.00E+00 4.72E+07 - - - 7.1688 0.9996 221125_WJC_METTL3_EV_vs_WT_F03.24397.24397.3 1.14E-07 24/76 K.TLFTNPIFPVGFSTGHNAPR.K sp|Q5T3J3|LRIF1_HUMAN 1 2172.1116 1.4 38787 24397 3 2173.114207 725.0445 Ligand-dependent nuclear receptor-interacting factor 1 OS=Homo sapiens OX=9606 GN=LRIF1 PE=1 SV=1 9.44 3766.7 - 1.21E+06 - - - 461.5711 - 3.902 0.532 - 614.8 1 2 0 1.0026 20 0 0 0 3.19E+07 2.28E+07 - - - 7.4966 0.9947 221125_WJC_METTL3_EV_vs_WT_F03.24398.24398.4 0.0261 17/126 K.EVIELPVKHPELFEALGIAQPK.G "sp|P62195|PRS8_HUMAN,tr|J3QQM1|J3QQM1_HUMAN,tr|J3KRP2|J3KRP2_HUMAN,tr|J3QRR3|J3QRR3_HUMAN,tr|J3QSA9|J3QSA9_HUMAN,tr|J3QLH6|J3QLH6_HUMAN,tr|J3QSE0|J3QSE0_HUMAN,tr|J3QRW1|J3QRW1_HUMAN" 8 2456.3679 1 38788 24398 4 2456.366079 615.0993 26S proteasome regulatory subunit 8 OS=Homo sapiens OX=9606 GN=PSMC5 PE=1 SV=1 4.91 3766.9 - 1.18E+06 - - - -0.7405 - 2.444 0.277 - 132.6 1 2 1 -0.0018 22 0 0 0 9.40E+06 9.43E+06 - - - 1.9289 0.9935 221125_WJC_METTL3_EV_vs_WT_F03.24399.24399.4 0.00141 17/126 K.EVIELPVK[136.11]HPELFEALGIAQPK[136.11].G "sp|P62195|PRS8_HUMAN,tr|J3QQM1|J3QQM1_HUMAN,tr|J3KRP2|J3KRP2_HUMAN,tr|J3QRR3|J3QRR3_HUMAN,tr|J3QSA9|J3QSA9_HUMAN,tr|J3QLH6|J3QLH6_HUMAN,tr|J3QSE0|J3QSE0_HUMAN,tr|J3QRW1|J3QRW1_HUMAN" 8 2472.3963 1 38789 24399 4 2472.392187 619.1064 26S proteasome regulatory subunit 8 OS=Homo sapiens OX=9606 GN=PSMC5 PE=1 SV=1 4.91 3767 - 1.09E+06 - - - -1.6628 - 2.259 0.278 - 125.3 1 2 1 -0.0041 22 0 0 0 9.40E+06 9.43E+06 - - - 1.9112 0.998 221125_WJC_METTL3_EV_vs_WT_F03.24401.24401.2 4.66E-07 30-Nov K.SVISGGLDALEFIGK[136.11]K[136.11].T "sp|Q9NRY5|F1142_HUMAN,tr|E7ESJ7|E7ESJ7_HUMAN,tr|E5RGF9|E5RGF9_HUMAN" 3 1648.9371 0.74 38791 24401 2 1648.928657 825.4758 Protein FAM114A2 OS=Homo sapiens OX=9606 GN=FAM114A2 PE=1 SV=4 5.79 3767.2 - 899385 - - - -5.1039 - 2.651 0.523 - 303.9 1 2 0 -0.0084 16 0 0 0 7.94E+06 1.07E+07 - - - 5.2982 1 221125_WJC_METTL3_EV_vs_WT_F03.24402.24402.2 2.12E-13 Dec-32 F.AQFGSDLDAATQQLLSR.G sp|P25705|ATPA_HUMAN 1 1819.9064 4.37 38792 24402 2 1819.903119 910.9605 "ATP synthase subunit alpha, mitochondrial OS=Homo sapiens OX=9606 GN=ATP5F1A PE=1 SV=1" 4.21 3767.4 - 514985 - - - -1.8254 - 2.92 0.696 - 387 1 1 0 -0.0033 17 0 0 0 4.35E+06 9.95E+05 - - - 6.8152 1 221125_WJC_METTL3_EV_vs_WT_F03.24407.24407.2 3.33E-13 24/42 K.SSVTSAAAVSALAGVQDQLIEK.R "sp|Q9HAF1|EAF6_HUMAN,tr|B1AK63|B1AK63_HUMAN" 2 2144.1325 1.67 38795 24407 2 2144.132667 1073.0735 Chromatin modification-related protein MEAF6 OS=Homo sapiens OX=9606 GN=MEAF6 PE=1 SV=1 4.37 3767.9 - 2.35E+06 - - - 0.0881 - 4.666 0.627 - 1558.7 1 2 0 0.0002 22 0 0 0 2.82E+07 1.69E+07 - - - 7.4589 1 221125_WJC_METTL3_EV_vs_WT_F03.24408.24408.3 3.98E-06 18/84 K.SSVTSAAAVSALAGVQDQLIEK[136.11].R "sp|Q9HAF1|EAF6_HUMAN,tr|B1AK63|B1AK63_HUMAN" 2 2152.1467 1.37 38796 24408 3 2152.148938 718.3895 Chromatin modification-related protein MEAF6 OS=Homo sapiens OX=9606 GN=MEAF6 PE=1 SV=1 4.37 3768 - 8.48E+06 - - - 1.0501 - 3.521 0.488 - 371.1 1 2 0 0.0023 22 0 0 0 9.76E+07 7.13E+07 - - - 6.9644 1 221125_WJC_METTL3_EV_vs_WT_F03.24410.24410.2 1.78E-15 25/46 K.SHLSTAGGLAVPSLPTAGPYYSPY.A sp|Q9H7S9|ZN703_HUMAN 1 2405.1903 - 38798 24410 2 2405.189361 1203.6024 Zinc finger protein 703 OS=Homo sapiens OX=9606 GN=ZNF703 PE=1 SV=1 6.46 3768.1 - 2.32E+06 - - - -0.4016 - 4.372 0.771 - 1063.3 1 1 0 -0.001 24 0 0 0 - - - - - 8.3622 0.9998 221125_WJC_METTL3_EV_vs_WT_F03.24414.24414.3 1.49E-06 18/68 R.IGPYQPNVPVGIDYVIPK.T "sp|P43243|MATR3_HUMAN,tr|B3KM87|B3KM87_HUMAN,tr|A8MXP9|A8MXP9_HUMAN,tr|A0A0R4J2E8|A0A0R4J2E8_HUMAN" 4 1968.072 1.67 38802 24414 3 1968.081493 657.0313 Matrin-3 OS=Homo sapiens OX=9606 GN=MATR3 PE=1 SV=2 5.83 3768.6 - 854305 - - - 4.7981 - 2.936 0.562 - 333.2 1 2 0 0.0094 18 0 0 0 6.12E+07 3.67E+07 - - - 7.4851 1 221125_WJC_METTL3_EV_vs_WT_F03.24415.24415.3 7.47E-12 24/68 K.GHVDILAPTVQELAALEK.E "sp|Q92499|DDX1_HUMAN,tr|A0A7I2V2M5|A0A7I2V2M5_HUMAN,tr|A0A087X2G1|A0A087X2G1_HUMAN,tr|A0A7I2V430|A0A7I2V430_HUMAN,tr|A0A7I2V4F0|A0A7I2V4F0_HUMAN,tr|A0A087WZ71|A0A087WZ71_HUMAN,tr|A0A7I2YQ77|A0A7I2YQ77_HUMAN" 7 1903.0415 1.44 38803 24415 3 1903.044128 635.3544 ATP-dependent RNA helicase DDX1 OS=Homo sapiens OX=9606 GN=DDX1 PE=1 SV=2 4.65 3768.7 - 761706 - - - 1.3925 - 4.237 0.585 - 965.7 1 2 0 0.0027 18 0 0 0 1.90E+08 1.32E+08 - - - 8.6568 1 221125_WJC_METTL3_EV_vs_WT_F03.24422.24422.3 8.39E-06 19/68 K.GHVDILAPTVQELAALEK[136.11].E "sp|Q92499|DDX1_HUMAN,tr|A0A7I2V2M5|A0A7I2V2M5_HUMAN,tr|A0A087X2G1|A0A087X2G1_HUMAN,tr|A0A7I2V430|A0A7I2V430_HUMAN,tr|A0A7I2V4F0|A0A7I2V4F0_HUMAN,tr|A0A087WZ71|A0A087WZ71_HUMAN,tr|A0A7I2YQ77|A0A7I2YQ77_HUMAN" 7 1911.0557 1.44 38808 24422 3 1911.053812 638.0258 ATP-dependent RNA helicase DDX1 OS=Homo sapiens OX=9606 GN=DDX1 PE=1 SV=2 4.65 3769.4 - 1.61E+06 - - - -0.9764 - 3.817 0.499 - 554.8 1 2 0 -0.0019 18 0 0 0 1.90E+08 1.32E+08 - - - 7.4382 1 221125_WJC_METTL3_EV_vs_WT_F03.24423.24423.2 2.57E-09 16/30 R.SDPDLVAQNIDVVLNR[166.11].R "sp|Q9UBU9|NXF1_HUMAN,tr|B4E227|B4E227_HUMAN,tr|E9PIN3|E9PIN3_HUMAN" 3 1776.9245 0.99 38809 24423 2 1776.921512 889.4695 Nuclear RNA export factor 1 OS=Homo sapiens OX=9606 GN=NXF1 PE=1 SV=1 3.93 3769.5 - 1.32E+06 - - - -1.708 - 3.092 0.671 - 699.7 1 2 0 -0.003 16 0 0 0 1.87E+07 1.89E+07 - - - 6.7713 1 221125_WJC_METTL3_EV_vs_WT_F03.24425.24425.3 3.76E-10 Dec-68 R.VTGVTNYVMQYVTVPLRK.C sp|Q8IWC1|MA7D3_HUMAN 1 2067.1187 1.7 38811 24425 3 2067.118237 690.0468 MAP7 domain-containing protein 3 OS=Homo sapiens OX=9606 GN=MAP7D3 PE=1 SV=2 9.7 3769.7 - 938093 - - - -0.2153 - 2.634 0.571 - 174.2 1 2 0 -0.0004 18 0 0 0 1.76E+07 1.04E+07 - - - 7.3176 1 221125_WJC_METTL3_EV_vs_WT_F03.24427.24427.2 1.27E-06 18/34 R.IGPYQPNVPVGIDYVIPK.T "sp|P43243|MATR3_HUMAN,tr|B3KM87|B3KM87_HUMAN,tr|A8MXP9|A8MXP9_HUMAN,tr|A0A0R4J2E8|A0A0R4J2E8_HUMAN" 4 1968.072 1.58 38813 24427 2 1968.072891 985.0433 Matrin-3 OS=Homo sapiens OX=9606 GN=MATR3 PE=1 SV=2 5.83 3770 - 733365 - - - 0.4273 - 2.705 0.594 - 658.2 1 2 0 0.0008 18 0 0 0 5.38E+07 3.41E+07 - - - 5.8745 1 221125_WJC_METTL3_EV_vs_WT_F03.24428.24428.3 7.91E-11 28/104 K.LSDALAVEDDQVAPVPLNVVETSSSVR.E sp|Q86UP2|KTN1_HUMAN 1 2809.4345 1.92 38814 24428 3 2809.436803 937.4855 Kinectin OS=Homo sapiens OX=9606 GN=KTN1 PE=1 SV=1 3.77 3770.1 - 554764 - - - 0.808 - 4.277 0.695 - 683.6 1 2 0 0.0023 27 0 0 0 2.55E+07 1.33E+07 - - - 9.6313 1 221125_WJC_METTL3_EV_vs_WT_F03.24429.24429.3 3.48E-09 16/104 K.LSDALAVEDDQVAPVPLNVVETSSSVR[166.11].E sp|Q86UP2|KTN1_HUMAN 1 2819.4428 1.95 38815 24429 3 2819.438518 940.8215 Kinectin OS=Homo sapiens OX=9606 GN=KTN1 PE=1 SV=1 3.77 3770.3 - 498295 - - - -1.5198 - 3.129 0.518 - 175.4 1 2 0 -0.0043 27 0 0 0 2.55E+07 1.31E+07 - - - 6.9384 1 221125_WJC_METTL3_EV_vs_WT_F03.24432.24432.4 3.08E-13 38/186 R.VVYGGGAAEISC[160.03]ALAVSQEADKC[160.03]PTLEQYAMR.A "sp|P48643|TCPE_HUMAN,tr|E9PCA1|E9PCA1_HUMAN,tr|B7ZAR1|B7ZAR1_HUMAN,tr|E7ENZ3|E7ENZ3_HUMAN" 4 3443.616 0.6 38816 24432 4 3443.616343 861.9113 T-complex protein 1 subunit epsilon OS=Homo sapiens OX=9606 GN=CCT5 PE=1 SV=1 4.41 3770.7 - 2.96E+06 - - - 0.1106 - 6.338 0.706 - 840.7 1 2 1 0.0004 32 0 0 0 5.23E+07 8.76E+07 - - - 5.9285 0.9999 221125_WJC_METTL3_EV_vs_WT_F03.24433.24433.3 1.34E-05 Nov-60 R.SDPDLVAQNIDVVLNR[166.11].R "sp|Q9UBU9|NXF1_HUMAN,tr|B4E227|B4E227_HUMAN,tr|E9PIN3|E9PIN3_HUMAN" 3 1776.9245 0.65 38817 24433 3 1776.922881 593.3155 Nuclear RNA export factor 1 OS=Homo sapiens OX=9606 GN=NXF1 PE=1 SV=1 3.93 3770.7 - 1.60E+06 - - - -0.9376 - 2.259 0.454 - 160.6 1 2 0 -0.0017 16 0 0 0 8.33E+06 1.28E+07 - - - 5.6922 0.9998 221125_WJC_METTL3_EV_vs_WT_F03.24435.24435.2 1.73E-05 15/34 R.IGPYQPNVPVGIDYVIPK[136.11].T "sp|P43243|MATR3_HUMAN,tr|B3KM87|B3KM87_HUMAN,tr|A8MXP9|A8MXP9_HUMAN,tr|A0A0R4J2E8|A0A0R4J2E8_HUMAN" 4 1976.0863 1.58 38819 24435 2 1976.089425 989.0504 Matrin-3 OS=Homo sapiens OX=9606 GN=MATR3 PE=1 SV=2 5.83 3771 - 665478 - - - 1.6067 - 2.411 0.534 - 398 1 2 0 0.0032 18 0 0 0 5.38E+07 3.41E+07 - - - 5.1477 0.9999 221125_WJC_METTL3_EV_vs_WT_F03.24436.24436.3 6.13E-06 Dec-56 R.MQQQLDEYQELLDIK.L "sp|P02545|LMNA_HUMAN,tr|A0A804HL68|A0A804HL68_HUMAN,tr|Q5TCI8|Q5TCI8_HUMAN,tr|A0A6Q8PFJ0|A0A6Q8PFJ0_HUMAN,tr|A0A6Q8PHQ9|A0A6Q8PHQ9_HUMAN,tr|Q3BDU5|Q3BDU5_HUMAN" 6 1892.919 1.23 38820 24436 3 1892.915722 631.9803 Prelamin-A\C OS=Homo sapiens OX=9606 GN=LMNA PE=1 SV=1 3.92 3771.1 - 526114 - - - -1.7212 - 2.413 0.449 - 152.6 1 2 0 -0.0033 15 0 0 0 7.38E+06 6.02E+06 - - - 5.8435 1 221125_WJC_METTL3_EV_vs_WT_F03.24441.24441.3 8.73E-14 26/96 R.LFDHPESPTPNPTEPLFLAQAEVYK[136.11].E "sp|P49327|FAS_HUMAN,tr|A0A0U1RQF0|A0A0U1RQF0_HUMAN" 2 2847.4211 0.81 38823 24441 3 2847.422512 950.1476 Fatty acid synthase OS=Homo sapiens OX=9606 GN=FASN PE=1 SV=3 4.4 3771.8 - 1.68E+06 - - - 0.5092 - 4.415 0.683 - 683.8 1 2 0 0.0014 25 0 0 0 3.27E+07 4.05E+07 - - - 9.5708 0.9982 221125_WJC_METTL3_EV_vs_WT_F03.24442.24442.3 5.17E-08 21/64 N.QSLLQPLNVEIDPEIQK.V sp|P04264|K2C1_HUMAN 1 1963.0626 12.95 38824 24442 3 1963.064485 655.3615 "Keratin, type II cytoskeletal 1 OS=Homo sapiens OX=9606 GN=KRT1 PE=1 SV=6" 4.14 3771.9 - 2.31E+06 - - - 0.9567 - 3.303 0.527 - 519.1 1 1 0 0.0019 17 0 0 0 1.47E+08 1.14E+07 - - - 7.4335 0.9997 221125_WJC_METTL3_EV_vs_WT_F03.24443.24443.3 0.00158 Dec-56 R.VISGVLQLGNIVFKK.E sp|P35579|MYH9_HUMAN 1 1613.9869 0.83 38825 24443 3 1613.987459 539.0029 Myosin-9 OS=Homo sapiens OX=9606 GN=MYH9 PE=1 SV=4 10 3771.9 - 1.73E+06 - - - 0.3687 - 2.059 0.34 - 145.9 1 2 0 0.0006 15 0 0 0 1.81E+07 2.18E+07 - - - 4.215 1 221125_WJC_METTL3_EV_vs_WT_F03.24445.24445.3 1.72E-08 15/104 K.NFQNIFPPSATLHLSNIPPSVSEEDLK[136.11].V "sp|P26599|PTBP1_HUMAN,tr|A0A0U1RRM4|A0A0U1RRM4_HUMAN,tr|A6NLN1|A6NLN1_HUMAN,tr|A0A0D9SF20|A0A0D9SF20_HUMAN,tr|A0A7I2V621|A0A7I2V621_HUMAN" 5 3001.5277 1.17 38827 24445 3 3001.529611 1001.5165 Polypyrimidine tract-binding protein 1 OS=Homo sapiens OX=9606 GN=PTBP1 PE=1 SV=1 4.65 3772.2 - 872276 - - - 0.6527 - 2.785 0.556 - 114 1 2 0 0.002 27 0 0 0 1.82E+07 1.56E+07 - - - 7.0947 0.9999 221125_WJC_METTL3_EV_vs_WT_F03.24446.24446.3 3.23E-08 17/52 K.ESNTVFSFLGLKPR.L sp|Q9UJC5|SH3L2_HUMAN 1 1593.8515 0.7 38828 24446 3 1593.854919 532.2911 SH3 domain-binding glutamic acid-rich-like protein 2 OS=Homo sapiens OX=9606 GN=SH3BGRL2 PE=1 SV=2 8.85 3772.3 - 523989 - - - 2.1501 - 2.938 0.476 - 479 1 2 0 0.0034 14 0 0 0 1.05E+07 1.50E+07 - - - 6.7101 0.9983 221125_WJC_METTL3_EV_vs_WT_F03.24447.24447.3 0.000282 Dec-56 K.LVEEIEQMNNLFQQK.Q sp|Q13625|ASPP2_HUMAN 1 1861.9244 2.67 38829 24447 3 1861.927734 621.6487 Apoptosis-stimulating of p53 protein 2 OS=Homo sapiens OX=9606 GN=TP53BP2 PE=1 SV=2 4.25 3772.5 - 396370 - - - 1.7912 - 2.527 0.21 - 206.6 1 2 0 0.0033 15 0 0 0 5.56E+06 2.08E+06 - - - 3.2993 0.9992 221125_WJC_METTL3_EV_vs_WT_F03.24448.24448.3 0.03 Nov-56 K.VSQEILELLNTTTAK[136.11].E "sp|Q86U44|MTA70_HUMAN,tr|H0YFV6|H0YFV6_HUMAN" 2 1666.9233 0.02 38830 24448 3 1666.924038 556.6484 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 4.53 3772.6 - 310956 - - - 0.4625 - 1.877 0.292 - 48.7 1 2 0 0.0008 15 0 0 0 6.75E+04 3.68E+06 - - - 3.4384 1 221125_WJC_METTL3_EV_vs_WT_F03.24451.24451.2 2.06E-05 15/32 N.QSLLQPLNVEIDPEIQK.V sp|P04264|K2C1_HUMAN 1 1963.0626 19.36 38831 24451 2 1963.062869 982.5386 "Keratin, type II cytoskeletal 1 OS=Homo sapiens OX=9606 GN=KRT1 PE=1 SV=6" 4.14 3773 - 2.78E+06 - - - 0.1335 - 3.274 0.564 - 533.3 1 1 0 0.0003 17 0 0 0 1.20E+08 6.20E+06 - - - 6.1225 1 221125_WJC_METTL3_EV_vs_WT_F03.24452.24452.3 2.21E-06 14/68 R.IGPYQPNVPVGIDYVIPK[136.11].T "sp|P43243|MATR3_HUMAN,tr|B3KM87|B3KM87_HUMAN,tr|A8MXP9|A8MXP9_HUMAN,tr|A0A0R4J2E8|A0A0R4J2E8_HUMAN" 4 1976.0863 1.67 38832 24452 3 1976.088528 659.7027 Matrin-3 OS=Homo sapiens OX=9606 GN=MATR3 PE=1 SV=2 5.83 3773 - 1.89E+06 - - - 1.1528 - 2.751 0.515 - 192.9 1 2 0 0.0023 18 0 0 0 6.12E+07 3.67E+07 - - - 6.801 1 221125_WJC_METTL3_EV_vs_WT_F03.24454.24454.3 1.85E-15 23/104 R.ALYDAELSQMQTHISDTSVVLSMDNNR.N "sp|P48668|K2C6C_HUMAN,sp|P04259|K2C6B_HUMAN,sp|P02538|K2C6A_HUMAN" 3 3037.4121 999 38834 24454 3 3037.416023 1013.478 "Keratin, type II cytoskeletal 6C OS=Homo sapiens OX=9606 GN=KRT6C PE=1 SV=3" 4.22 3773.3 - 822399 - - - 1.2916 - 4.434 0.728 - 585.4 1 2 0 0.0039 27 0 0 0 2.70E+08 0.00E+00 - - - 10.0817 1 221125_WJC_METTL3_EV_vs_WT_F03.24455.24455.3 2.26E-06 21/104 K.LSDALAVEDDQVAPVPLNVVETSSSVR[166.11].E sp|Q86UP2|KTN1_HUMAN 1 2819.4428 1.95 38835 24455 3 2819.446399 940.8215 Kinectin OS=Homo sapiens OX=9606 GN=KTN1 PE=1 SV=1 3.77 3773.4 - 785776 - - - 1.2754 - 3.636 0.505 - 331.5 1 2 0 0.0036 27 0 0 0 2.55E+07 1.31E+07 - - - 7.1391 1 221125_WJC_METTL3_EV_vs_WT_F03.24456.24456.3 6.56E-13 23/116 Q.AAGLSVPNVHGALAPLAIPSAAAAAAAAGR.L "tr|A0A0U1RRM4|A0A0U1RRM4_HUMAN,tr|A6NLN1|A6NLN1_HUMAN,tr|A0A7I2V621|A0A7I2V621_HUMAN,tr|A0A087WTS6|A0A087WTS6_HUMAN,tr|K7EK45|K7EK45_HUMAN" 5 2635.4558 1.25 38836 24456 3 2635.454784 879.4925 Polypyrimidine tract-binding protein 1 OS=Homo sapiens OX=9606 GN=PTBP1 PE=1 SV=1 9.8 3773.6 - 674259 - - - -0.3923 - 4.032 0.627 - 206.7 1 1 0 -0.001 30 0 0 0 1.45E+07 1.16E+07 - - - 8.7378 0.9995 221125_WJC_METTL3_EV_vs_WT_F03.24458.24458.2 0.000122 24-Sep K.ELDQWIEQLNEC[160.03]K[136.11].Q "sp|P67775|PP2AA_HUMAN,tr|E5RI56|E5RI56_HUMAN" 2 1711.7967 0.38 38838 24458 2 1711.793158 856.9056 Serine\threonine-protein phosphatase 2A catalytic subunit alpha isoform OS=Homo sapiens OX=9606 GN=PPP2CA PE=1 SV=1 4 3773.8 - 634889 - - - -2.061 - 2.301 0.381 - 333.2 1 2 0 -0.0035 13 0 0 0 3.04E+06 7.97E+06 - - - 3.9928 0.9999 221125_WJC_METTL3_EV_vs_WT_F03.24462.24462.3 6.32E-05 14/48 K.TVNAVVEFFQSNK[136.11].G sp|Q709C8|VP13C_HUMAN 1 1489.7656 0.61 38842 24462 3 1489.768077 497.5958 Vacuolar protein sorting-associated protein 13C OS=Homo sapiens OX=9606 GN=VPS13C PE=1 SV=1 5.66 3774.4 - 304374 - - - 1.6331 - 2.685 0.441 - 168.5 1 2 0 0.0024 13 0 0 0 1.49E+06 2.45E+06 - - - 6.1339 1 221125_WJC_METTL3_EV_vs_WT_F03.24466.24466.3 5.48E-16 42/124 R.VVYGGGAAEISC[160.03]ALAVSQEADK[136.11]C[160.03]PTLEQYAMR[166.11].A "sp|P48643|TCPE_HUMAN,tr|E9PCA1|E9PCA1_HUMAN,tr|B7ZAR1|B7ZAR1_HUMAN,tr|E7ENZ3|E7ENZ3_HUMAN" 4 3461.6384 0.7 38844 24466 3 3461.63529 1154.8868 T-complex protein 1 subunit epsilon OS=Homo sapiens OX=9606 GN=CCT5 PE=1 SV=1 4.41 3774.9 - 4.72E+06 - - - -0.9077 - 6.617 0.667 - 1788.4 1 2 1 -0.0031 32 0 0 0 3.54E+07 5.04E+07 - - - 10.3229 1 221125_WJC_METTL3_EV_vs_WT_F03.24467.24467.3 6.22E-11 38/124 R.VVYGGGAAEISC[160.03]ALAVSQEADKC[160.03]PTLEQYAMR.A "sp|P48643|TCPE_HUMAN,tr|E9PCA1|E9PCA1_HUMAN,tr|B7ZAR1|B7ZAR1_HUMAN,tr|E7ENZ3|E7ENZ3_HUMAN" 4 3443.616 0.7 38845 24467 3 3443.616247 1148.8793 T-complex protein 1 subunit epsilon OS=Homo sapiens OX=9606 GN=CCT5 PE=1 SV=1 4.41 3775 - 3.36E+06 - - - 0.0828 - 6.406 0.642 - 1264.8 1 2 1 0.0003 32 0 0 0 3.54E+07 5.04E+07 - - - 9.9704 1 221125_WJC_METTL3_EV_vs_WT_F03.24468.24468.4 2.92E-12 35/186 R.VVYGGGAAEISC[160.03]ALAVSQEADK[136.11]C[160.03]PTLEQYAMR[166.11].A "sp|P48643|TCPE_HUMAN,tr|E9PCA1|E9PCA1_HUMAN,tr|B7ZAR1|B7ZAR1_HUMAN,tr|E7ENZ3|E7ENZ3_HUMAN" 4 3461.6384 0.6 38846 24468 4 3461.639035 866.4169 T-complex protein 1 subunit epsilon OS=Homo sapiens OX=9606 GN=CCT5 PE=1 SV=1 4.41 3775.1 - 8.54E+06 - - - 0.1742 - 5.619 0.649 - 647.2 1 2 1 0.0006 32 0 0 0 5.23E+07 8.76E+07 - - - 5.3959 1 221125_WJC_METTL3_EV_vs_WT_F03.24469.24469.3 1.20E-12 20/96 R.LFDHPESPTPNPTEPLFLAQAEVYK.E "sp|P49327|FAS_HUMAN,tr|A0A0U1RQF0|A0A0U1RQF0_HUMAN" 2 2839.4069 0.81 38847 24469 3 2839.408549 947.4762 Fatty acid synthase OS=Homo sapiens OX=9606 GN=FASN PE=1 SV=3 4.4 3775.1 - 2.12E+06 - - - 0.5941 - 3.908 0.694 - 318.9 1 2 0 0.0017 25 0 0 0 3.27E+07 4.05E+07 - - - 9.4128 1 221125_WJC_METTL3_EV_vs_WT_F03.24470.24470.3 4.73E-10 22/84 R.LPIGNTIQPSQAATFMNDAIEK.A sp|O43395|PRPF3_HUMAN 1 2358.1889 2.23 38848 24470 3 2358.193506 787.0703 U4\U6 small nuclear ribonucleoprotein Prp3 OS=Homo sapiens OX=9606 GN=PRPF3 PE=1 SV=2 4.37 3775.3 - 1.19E+06 - - - 1.9333 - 3.53 0.579 - 469 1 2 0 0.0046 22 0 0 0 1.88E+08 8.45E+07 - - - 7.9843 1 221125_WJC_METTL3_EV_vs_WT_F03.24471.24471.3 3.32E-14 23/96 K.IDATQVEVNPFGETPEGQVVC[160.03]FDAK.L "sp|Q96I99|SUCB2_HUMAN,tr|E9PDQ8|E9PDQ8_HUMAN" 2 2749.2905 4.89 38849 24471 3 2749.288384 917.4374 "Succinate--CoA ligase [GDP-forming] subunit beta, mitochondrial OS=Homo sapiens OX=9606 GN=SUCLG2 PE=1 SV=2" 3.83 3775.4 - 1.00E+06 - - - -0.774 - 4.398 0.623 - 631 1 2 0 -0.0021 25 0 0 0 5.37E+06 1.10E+06 - - - 8.8928 0.9983 221125_WJC_METTL3_EV_vs_WT_F03.24472.24472.4 6.88E-12 27/96 S.PSELFAQHIVTIVHHVK.E "sp|Q9Y2W1|TR150_HUMAN,tr|A0A3B3ITZ9|A0A3B3ITZ9_HUMAN" 2 1954.0789 2.43 38850 24472 4 1954.079887 489.527 Thyroid hormone receptor-associated protein 3 OS=Homo sapiens OX=9606 GN=THRAP3 PE=1 SV=2 7.42 3775.6 - 865350 - - - 0.5225 - 4.249 0.593 - 757.7 1 1 0 0.001 17 0 0 0 1.59E+07 6.55E+06 - - - 4.8895 1 221125_WJC_METTL3_EV_vs_WT_F03.24473.24473.3 0.00637 Nov-56 R.VISGVLQLGNIVFK[136.11]K[136.11].E sp|P35579|MYH9_HUMAN 1 1630.0153 0.83 38851 24473 3 1630.014078 544.3457 Myosin-9 OS=Homo sapiens OX=9606 GN=MYH9 PE=1 SV=4 10 3775.7 - 833112 - - - -0.7276 - 2.305 0.471 - 126.7 1 2 0 -0.0012 15 0 0 0 1.81E+07 2.18E+07 - - - 5.9699 1 221125_WJC_METTL3_EV_vs_WT_F03.24474.24474.2 1.77E-12 16/30 R.SDPDLVAQNIDVVLNR.R "sp|Q9UBU9|NXF1_HUMAN,tr|B4E227|B4E227_HUMAN,tr|E9PIN3|E9PIN3_HUMAN" 3 1766.9163 0.99 38852 24474 2 1766.919124 884.4654 Nuclear RNA export factor 1 OS=Homo sapiens OX=9606 GN=NXF1 PE=1 SV=1 3.93 3775.8 - 730998 - - - 1.6113 - 3.106 0.664 - 714.6 1 2 0 0.0028 16 0 0 0 1.87E+07 1.89E+07 - - - 6.7308 0.9996 221125_WJC_METTL3_EV_vs_WT_F03.24475.24475.3 0.00076 Dec-44 K.DK[136.11]LTPWEQFLEK[136.11].K "sp|Q9H501|ESF1_HUMAN,tr|A0A087WX71|A0A087WX71_HUMAN" 2 1548.8159 0.45 38853 24475 3 1548.815251 517.2792 ESF1 homolog OS=Homo sapiens OX=9606 GN=ESF1 PE=1 SV=1 4.68 3775.9 - 708670 - - - -0.4158 - 2.259 0.4 - 174.9 1 2 1 -0.0006 12 0 0 0 7.22E+06 1.62E+07 - - - 5.2583 0.9998 221125_WJC_METTL3_EV_vs_WT_F03.24476.24476.2 6.27E-09 18/34 K.GHVDILAPTVQELAALEK[136.11].E "sp|Q92499|DDX1_HUMAN,tr|A0A7I2V2M5|A0A7I2V2M5_HUMAN,tr|A0A087X2G1|A0A087X2G1_HUMAN,tr|A0A7I2V430|A0A7I2V430_HUMAN,tr|A0A7I2V4F0|A0A7I2V4F0_HUMAN,tr|A0A087WZ71|A0A087WZ71_HUMAN,tr|A0A7I2YQ77|A0A7I2YQ77_HUMAN" 7 1911.0557 1.29 38854 24476 2 1911.05821 956.5351 ATP-dependent RNA helicase DDX1 OS=Homo sapiens OX=9606 GN=DDX1 PE=1 SV=2 4.65 3776.1 - 462811 - - - 1.3249 - 3.17 0.349 - 972.5 1 2 0 0.0025 18 0 0 0 6.23E+06 4.82E+06 - - - 4.4544 1 221125_WJC_METTL3_EV_vs_WT_F03.24477.24477.3 1.05E-06 15/52 R.DTFNHLTTWLEDAR.Q "sp|P61019|RAB2A_HUMAN,tr|H7C125|H7C125_HUMAN,tr|E9PKL7|E9PKL7_HUMAN" 3 1717.806 1.15 38855 24477 3 1717.804126 573.6093 Ras-related protein Rab-2A OS=Homo sapiens OX=9606 GN=RAB2A PE=1 SV=1 4.54 3776.2 - 423747 - - - -1.0903 - 2.625 0.588 - 274.3 1 2 0 -0.0019 14 0 0 0 2.67E+07 2.32E+07 - - - 7.6598 0.9982 221125_WJC_METTL3_EV_vs_WT_F03.24480.24480.3 0.0281 Nov-32 R.DLLQFFK[136.11]PR[166.11].Q "sp|Q93009|UBP7_HUMAN,tr|A0A669KBL1|A0A669KBL1_HUMAN,tr|H3BND8|H3BND8_HUMAN" 3 1180.6723 1.29 38858 24480 3 1180.671759 394.5647 Ubiquitin carboxyl-terminal hydrolase 7 OS=Homo sapiens OX=9606 GN=USP7 PE=1 SV=2 8.75 3776.6 - 227189 - - - -0.4997 - 1.875 0.22 - 186.3 1 2 0 -0.0006 9 0 0 0 1.84E+06 1.43E+06 - - - 2.8871 1 221125_WJC_METTL3_EV_vs_WT_F03.24484.24484.3 5.55E-10 17/72 K.LQQLFNHTMFILEQEEYQR.E "sp|P35580|MYH10_HUMAN,sp|P35749|MYH11_HUMAN,sp|P35579|MYH9_HUMAN,tr|A0A494C024|A0A494C024_HUMAN" 4 2466.2002 0.81 38860 24484 3 2466.198291 823.074 Myosin-10 OS=Homo sapiens OX=9606 GN=MYH10 PE=1 SV=3 4.75 3777.1 - 1.93E+06 - - - -0.766 - 3.629 0.607 - 437.2 1 2 0 -0.0019 19 0 0 0 1.31E+07 1.61E+07 - - - 8.4736 1 221125_WJC_METTL3_EV_vs_WT_F03.24485.24485.3 6.22E-13 23/72 K.LQQLFNHTMFILEQEEYQR[166.11].E "sp|P35580|MYH10_HUMAN,sp|P35749|MYH11_HUMAN,sp|P35579|MYH9_HUMAN,tr|A0A494C024|A0A494C024_HUMAN" 4 2476.2085 0.81 38861 24485 3 2476.207675 826.4101 Myosin-10 OS=Homo sapiens OX=9606 GN=MYH10 PE=1 SV=3 4.75 3777.2 - 1.88E+06 - - - -0.313 - 4.136 0.664 - 908.4 1 2 0 -0.0008 19 0 0 0 1.31E+07 1.61E+07 - - - 9.4307 1 221125_WJC_METTL3_EV_vs_WT_F03.24486.24486.4 7.03E-10 20/102 R.SPSELFAQHIVTIVHHVK.E "sp|Q9Y2W1|TR150_HUMAN,tr|A0A3B3ITZ9|A0A3B3ITZ9_HUMAN" 2 2041.1109 2.76 38862 24486 4 2041.113144 511.285 Thyroid hormone receptor-associated protein 3 OS=Homo sapiens OX=9606 GN=THRAP3 PE=1 SV=2 6.78 3777.3 - 991290 - - - 1.1019 - 3.075 0.514 - 281.1 1 2 0 0.0022 18 0 0 0 1.37E+07 4.99E+06 - - - 4.084 1 221125_WJC_METTL3_EV_vs_WT_F03.24487.24487.3 3.77E-09 21/104 K.NFQNIFPPSATLHLSNIPPSVSEEDLK.V "sp|P26599|PTBP1_HUMAN,tr|A0A0U1RRM4|A0A0U1RRM4_HUMAN,tr|A6NLN1|A6NLN1_HUMAN,tr|A0A0D9SF20|A0A0D9SF20_HUMAN,tr|A0A7I2V621|A0A7I2V621_HUMAN" 5 2993.5135 0.82 38863 24487 3 2993.521627 998.8451 Polypyrimidine tract-binding protein 1 OS=Homo sapiens OX=9606 GN=PTBP1 PE=1 SV=1 4.65 3777.4 - 853338 - - - 2.7309 - 3.391 0.568 - 279.4 1 2 0 0.0082 27 0 0 0 8.53E+06 1.04E+07 - - - 7.6797 0.9999 221125_WJC_METTL3_EV_vs_WT_F03.24489.24489.2 0.000565 20-Nov R.NPEAALSPTFR[166.11].S "sp|Q86U44|MTA70_HUMAN,tr|B4E349|B4E349_HUMAN,tr|F5H6D8|F5H6D8_HUMAN,tr|B4DTN4|B4DTN4_HUMAN" 4 1211.6174 0.001 38865 24489 2 1211.618305 606.816 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 6 3777.7 - 464500 - - - 0.7412 - 2.452 0.479 - 335.4 1 2 0 0.0009 11 0 0 0 0.00E+00 5.06E+06 - - - 5.0049 1 221125_WJC_METTL3_EV_vs_WT_F03.24490.24490.2 2.65E-07 15/34 K.PSTASAVPELATDPELEK[136.11].K "sp|Q86U44|MTA70_HUMAN,tr|B4E349|B4E349_HUMAN,tr|F5H6D8|F5H6D8_HUMAN,tr|H0YFV6|H0YFV6_HUMAN,tr|B4DTN4|B4DTN4_HUMAN" 5 1861.94 0.001 38866 24490 2 1862.938345 931.9773 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 4 3777.8 - 394247 - - - 536.1644 - 3.096 0.604 - 427.6 1 1 0 0.9983 18 0 0 0 0.00E+00 3.14E+07 - - - 5.9671 1 221125_WJC_METTL3_EV_vs_WT_F03.24494.24494.3 1.29E-09 16/68 R.GQC[160.03]DLELINVC[160.03]NENSLFK.S "sp|Q00610|CLH1_HUMAN,tr|A0A087WVQ6|A0A087WVQ6_HUMAN" 2 2151.9929 0.81 38868 24494 3 2151.992511 718.3382 Clathrin heavy chain 1 OS=Homo sapiens OX=9606 GN=CLTC PE=1 SV=5 4.14 3778.3 - 1.52E+06 - - - -0.1761 - 3.035 0.596 - 398.7 1 2 0 -0.0004 18 0 0 0 1.51E+07 1.87E+07 - - - 7.9492 1 221125_WJC_METTL3_EV_vs_WT_F03.24495.24495.3 8.51E-09 19/56 R.NIETIINTFHQYSVK.L sp|P06702|S10A9_HUMAN 1 1805.9312 6459.6 38869 24495 3 1805.933414 602.9843 Protein S100-A9 OS=Homo sapiens OX=9606 GN=S100A9 PE=1 SV=1 6.75 3778.4 - 3.84E+06 - - - 1.2265 - 3.427 0.569 - 335 1 2 0 0.0022 15 0 0 0 1.58E+09 2.45E+05 - - - 8.0971 1 221125_WJC_METTL3_EV_vs_WT_F03.24496.24496.3 5.86E-08 19/68 K.DNHLLGTFDLTGIPPAPR[166.11].G "sp|P11021|BIP_HUMAN,tr|A0A7P0TAI0|A0A7P0TAI0_HUMAN" 2 1943.014 0.69 38870 24496 3 1943.016689 648.6786 Endoplasmic reticulum chaperone BiP OS=Homo sapiens OX=9606 GN=HSPA5 PE=1 SV=2 5.21 3778.5 - 1.31E+06 - - - 1.368 - 3.294 0.598 - 311.6 1 2 0 0.0027 18 0 0 0 1.10E+07 1.59E+07 - - - 8.1748 1 221125_WJC_METTL3_EV_vs_WT_F03.24497.24497.3 4.67E-07 18/68 K.DNHLLGTFDLTGIPPAPR.G "sp|P11021|BIP_HUMAN,tr|A0A7P0TAI0|A0A7P0TAI0_HUMAN" 2 1933.0058 0.7 38871 24497 3 1933.009064 645.3425 Endoplasmic reticulum chaperone BiP OS=Homo sapiens OX=9606 GN=HSPA5 PE=1 SV=2 5.21 3778.6 - 813908 - - - 1.7087 - 3.237 0.494 - 253.3 1 2 0 0.0033 18 0 0 0 1.22E+07 1.76E+07 - - - 6.9717 0.9908 221125_WJC_METTL3_EV_vs_WT_F03.24501.24501.2 0.408 Aug-36 R.DTAEGVSQELISAGLVDGR.D sp|O95747|OXSR1_HUMAN 1 1915.9487 999 38875 24501 2 1915.950704 958.9816 Serine\threonine-protein kinase OSR1 OS=Homo sapiens OX=9606 GN=OXSR1 PE=1 SV=1 3.92 3779.1 - 533641 - - - 1.046 - 1.271 0.17 - 73.5 1 2 0 0.002 19 0 0 0 6.08E+06 0.00E+00 - - - 0.8856 1 221125_WJC_METTL3_EV_vs_WT_F03.24502.24502.2 4.34E-11 14/34 R.GQC[160.03]DLELINVC[160.03]NENSLFK.S "sp|Q00610|CLH1_HUMAN,tr|A0A087WVQ6|A0A087WVQ6_HUMAN" 2 2151.9929 1.38 38876 24502 2 2151.992532 1077.0037 Clathrin heavy chain 1 OS=Homo sapiens OX=9606 GN=CLTC PE=1 SV=5 4.14 3779.2 - 372176 - - - -0.1664 - 3.163 0.702 - 537 1 2 0 -0.0004 18 0 0 0 5.82E+06 4.21E+06 - - - 7.0569 1 221125_WJC_METTL3_EV_vs_WT_F03.24503.24503.4 8.91E-13 25/96 S.PSELFAQHIVTIVHHVK[136.11].E "sp|Q9Y2W1|TR150_HUMAN,tr|A0A3B3ITZ9|A0A3B3ITZ9_HUMAN" 2 1962.0931 2.43 38877 24503 4 1962.096993 491.5305 Thyroid hormone receptor-associated protein 3 OS=Homo sapiens OX=9606 GN=THRAP3 PE=1 SV=2 7.42 3779.4 - 312111 - - - 2.0014 - 4.184 0.647 - 543.2 1 1 0 0.0039 17 0 0 0 1.59E+07 6.55E+06 - - - 5.3533 0.9687 221125_WJC_METTL3_EV_vs_WT_F03.24504.24504.3 0.0605 Aug-32 R.DLLQFFKPR.Q "sp|Q93009|UBP7_HUMAN,tr|A0A669KBL1|A0A669KBL1_HUMAN,tr|H3BND8|H3BND8_HUMAN" 3 1162.6499 1.29 38878 24504 3 1162.65059 388.5572 Ubiquitin carboxyl-terminal hydrolase 7 OS=Homo sapiens OX=9606 GN=USP7 PE=1 SV=2 8.75 3779.5 - 263865 - - - 0.6115 - 1.351 0.151 - 103.8 1 2 0 0.0007 9 0 0 0 1.84E+06 1.43E+06 - - - 1.13 0.998 221125_WJC_METTL3_EV_vs_WT_F03.24505.24505.4 0.00187 Nov-90 K.EAVILPIKFPHLFTGK.R "sp|Q9UN37|VPS4A_HUMAN,sp|O75351|VPS4B_HUMAN,tr|I3L4J1|I3L4J1_HUMAN" 3 1809.0553 0.61 38879 24505 4 1809.057793 453.2711 Vacuolar protein sorting-associated protein 4A OS=Homo sapiens OX=9606 GN=VPS4A PE=1 SV=1 8.69 3779.6 - 181122 - - - 1.3902 - 2.133 0.333 - 98.3 1 2 1 0.0025 16 0 0 0 1.79E+06 2.91E+06 - - - 2.3906 1 221125_WJC_METTL3_EV_vs_WT_F03.24508.24508.4 3.31E-07 20/156 R.ALYDAELSQMQTHISDTSVVLSMDNNR.N "sp|P48668|K2C6C_HUMAN,sp|P04259|K2C6B_HUMAN,sp|P02538|K2C6A_HUMAN" 3 3037.4121 372.73 38880 24508 4 3037.414346 760.3603 "Keratin, type II cytoskeletal 6C OS=Homo sapiens OX=9606 GN=KRT6C PE=1 SV=3" 4.22 3780 - 8.36E+06 - - - 0.7394 - 2.94 0.545 - 169.9 1 2 0 0.0022 27 0 0 0 4.69E+07 1.26E+05 - - - 4.3065 1 221125_WJC_METTL3_EV_vs_WT_F03.24509.24509.2 2.84E-10 19/28 R.NIETIINTFHQYSVK.L sp|P06702|S10A9_HUMAN 1 1805.9312 999 38881 24509 2 1805.931956 903.9729 Protein S100-A9 OS=Homo sapiens OX=9606 GN=S100A9 PE=1 SV=1 6.75 3780.1 - 7.67E+06 - - - 0.4192 - 3.584 0.595 - 923.5 1 2 0 0.0008 15 0 0 0 2.17E+08 0.00E+00 - - - 6.5737 1 221125_WJC_METTL3_EV_vs_WT_F03.24512.24512.3 3.80E-08 14/68 R.EGNDLYHEMIESGVINLK.D "sp|P06576|ATPB_HUMAN,tr|F8W079|F8W079_HUMAN,tr|H0YI37|H0YI37_HUMAN,tr|F8W0P7|F8W0P7_HUMAN,tr|H0YH81|H0YH81_HUMAN" 5 2059.9885 1.66 38884 24512 3 2059.985739 687.6701 "ATP synthase subunit beta, mitochondrial OS=Homo sapiens OX=9606 GN=ATP5F1B PE=1 SV=3" 4.4 3780.3 - 2.61E+06 - - - -1.3189 - 2.645 0.584 - 267.2 1 2 0 -0.0027 18 0 0 0 9.53E+07 5.74E+07 - - - 7.4723 1 221125_WJC_METTL3_EV_vs_WT_F03.24514.24514.2 3.34E-13 18/42 R.LPIGNTIQPSQAATFMNDAIEK.A sp|O43395|PRPF3_HUMAN 1 2358.1889 3.54 38886 24514 2 2358.191041 1180.1017 U4\U6 small nuclear ribonucleoprotein Prp3 OS=Homo sapiens OX=9606 GN=PRPF3 PE=1 SV=2 4.37 3780.5 - 606332 - - - 0.888 - 4.188 0.672 - 551.5 1 2 0 0.0021 22 0 0 0 1.79E+07 5.07E+06 - - - 7.5249 1 221125_WJC_METTL3_EV_vs_WT_F03.24515.24515.2 2.46E-18 26/52 R.ALYDAELSQMQTHISDTSVVLSMDNNR.N "sp|P48668|K2C6C_HUMAN,sp|P04259|K2C6B_HUMAN,sp|P02538|K2C6A_HUMAN" 3 3037.4121 -1 38887 24515 2 3037.411378 1519.7133 "Keratin, type II cytoskeletal 6C OS=Homo sapiens OX=9606 GN=KRT6C PE=1 SV=3" 4.22 3780.7 - 0 - - - -0.2377 - 4.823 0.787 - 1390.3 1 2 0 -0.0007 27 0 0 0 0.00E+00 0.00E+00 - - - 8.7218 0.9999 221125_WJC_METTL3_EV_vs_WT_F03.24516.24516.3 0.000107 14/52 R.TESDDLHTFLLEIK.E "sp|P35658|NU214_HUMAN,tr|A0A0A0MSW3|A0A0A0MSW3_HUMAN,tr|A0A494BZU9|A0A494BZU9_HUMAN,tr|A0A494C1F2|A0A494C1F2_HUMAN" 4 1659.8356 2.09 38888 24516 3 1659.83117 554.2858 Nuclear pore complex protein Nup214 OS=Homo sapiens OX=9606 GN=NUP214 PE=1 SV=2 4.31 3780.8 - 580582 - - - -2.6491 - 2.281 0.465 - 205.8 1 2 0 -0.0044 14 0 0 0 7.91E+07 3.79E+07 - - - 5.9145 0.9998 221125_WJC_METTL3_EV_vs_WT_F03.24517.24517.3 7.31E-05 10/112 K.VSDSISAQYPVVDHEFDAVVVGAGGAGLR.A "sp|P31040|SDHA_HUMAN,tr|A0A087X1I3|A0A087X1I3_HUMAN,tr|D6RFM5|D6RFM5_HUMAN,tr|A0A494C1T6|A0A494C1T6_HUMAN" 4 2914.4461 0.9 38889 24517 3 2914.441092 972.4893 "Succinate dehydrogenase [ubiquinone] flavoprotein subunit, mitochondrial OS=Homo sapiens OX=9606 GN=SDHA PE=1 SV=2" 4.22 3780.9 - 489671 - - - -1.7187 - 2.214 0.401 - 46.5 1 2 0 -0.005 29 0 0 0 3.06E+06 3.39E+06 - - - 4.8379 1 221125_WJC_METTL3_EV_vs_WT_F03.24519.24519.4 2.62E-07 17/84 R.NIETIINTFHQYSVK.L sp|P06702|S10A9_HUMAN 1 1805.9312 999 38891 24519 4 1805.930249 452.4901 Protein S100-A9 OS=Homo sapiens OX=9606 GN=S100A9 PE=1 SV=1 6.75 3781.2 - 278330 - - - -0.526 - 3.119 0.496 - 259.5 1 2 0 -0.0009 15 0 0 0 4.50E+06 0.00E+00 - - - 3.9499 1 221125_WJC_METTL3_EV_vs_WT_F03.24527.24527.3 1.48E-06 16/64 R.TQLPYEYYSLPFC[160.03]QPSK[136.11].L "sp|Q92544|TM9S4_HUMAN,tr|F2Z2L1|F2Z2L1_HUMAN,tr|A0A0C4DFM1|A0A0C4DFM1_HUMAN,tr|F8WCN2|F8WCN2_HUMAN" 4 2128.0067 1.29 38897 24527 3 2128.008292 710.3428 Transmembrane 9 superfamily member 4 OS=Homo sapiens OX=9606 GN=TM9SF4 PE=1 SV=2 5.66 3781.9 - 1.52E+06 - - - 0.758 - 2.829 0.502 - 283.7 1 2 0 0.0016 17 0 0 0 2.24E+07 1.74E+07 - - - 6.7635 0.9999 221125_WJC_METTL3_EV_vs_WT_F03.24528.24528.3 0.000357 14/52 R.TESDDLHTFLLEIK[136.11].E "sp|P35658|NU214_HUMAN,tr|A0A0A0MSW3|A0A0A0MSW3_HUMAN,tr|A0A494BZU9|A0A494BZU9_HUMAN,tr|A0A494C1F2|A0A494C1F2_HUMAN" 4 1667.8498 2.09 38898 24528 3 1667.849225 556.9572 Nuclear pore complex protein Nup214 OS=Homo sapiens OX=9606 GN=NUP214 PE=1 SV=2 4.31 3782 - 1.51E+06 - - - -0.325 - 2.415 0.447 - 215.6 1 2 0 -0.0005 14 0 0 0 7.91E+07 3.79E+07 - - - 5.8666 1 221125_WJC_METTL3_EV_vs_WT_F03.24531.24531.3 6.99E-09 14/76 K.IDQLEGDHQLIQEALIFDNK[136.11].H "sp|P12814|ACTN1_HUMAN,tr|A0A804HK61|A0A804HK61_HUMAN,tr|H7C5W8|H7C5W8_HUMAN,tr|A0A804HJU8|A0A804HJU8_HUMAN,tr|A0A804HIN7|A0A804HIN7_HUMAN,tr|H0YJ11|H0YJ11_HUMAN,tr|H9KV75|H9KV75_HUMAN,tr|A0A804HLF4|A0A804HLF4_HUMAN,tr|H0YJW3|H0YJW3_HUMAN,tr|A0A7I2V4Y4|A0A7I2V4Y4_HUMAN,tr|A0A804HII9|A0A804HII9_HUMAN,tr|A0A804HL31|A0A804HL31_HUMAN,tr|A0A804HKE2|A0A804HKE2_HUMAN,tr|A0A804HLD0|A0A804HLD0_HUMAN" 14 2346.1947 0.97 38901 24531 3 2346.196093 783.0722 Alpha-actinin-1 OS=Homo sapiens OX=9606 GN=ACTN1 PE=1 SV=2 4.1 3782.4 - 1.18E+06 - - - 0.5976 - 3.394 0.548 - 283.4 1 2 0 0.0014 20 0 0 0 6.01E+06 6.19E+06 - - - 7.6139 0.9998 221125_WJC_METTL3_EV_vs_WT_F03.24532.24532.3 0.000116 18/52 K.EAINVEQAFQTIAR.N "sp|P51149|RAB7A_HUMAN,tr|C9J4V0|C9J4V0_HUMAN,tr|A0A6Q8PH84|A0A6Q8PH84_HUMAN,tr|C9J8S3|C9J8S3_HUMAN,tr|C9J4S4|C9J4S4_HUMAN,tr|A0A6Q8PGE6|A0A6Q8PGE6_HUMAN,tr|A0A6Q8PG52|A0A6Q8PG52_HUMAN" 7 1588.8209 1.26 38902 24532 3 1588.827381 530.6142 Ras-related protein Rab-7a OS=Homo sapiens OX=9606 GN=RAB7A PE=1 SV=1 4.53 3782.5 - 648883 - - - 4.0665 - 3.193 0.44 - 380.5 1 2 0 0.0065 14 0 0 0 2.80E+07 2.22E+07 - - - 6.5291 1 221125_WJC_METTL3_EV_vs_WT_F03.24533.24533.3 0.000399 19/52 K.EAINVEQAFQTIAR[166.11].N "sp|P51149|RAB7A_HUMAN,tr|C9J4V0|C9J4V0_HUMAN,tr|A0A6Q8PH84|A0A6Q8PH84_HUMAN,tr|C9J8S3|C9J8S3_HUMAN,tr|C9J4S4|C9J4S4_HUMAN,tr|A0A6Q8PGE6|A0A6Q8PGE6_HUMAN,tr|A0A6Q8PG52|A0A6Q8PG52_HUMAN" 7 1598.8292 1.26 38903 24533 3 1598.826246 533.9503 Ras-related protein Rab-7a OS=Homo sapiens OX=9606 GN=RAB7A PE=1 SV=1 4.53 3782.6 - 536019 - - - -1.8413 - 2.809 0.487 - 456.9 1 2 0 -0.0029 14 0 0 0 2.80E+07 2.21E+07 - - - 6.7135 0.9999 221125_WJC_METTL3_EV_vs_WT_F03.24534.24534.4 1.16E-06 13/102 R.SPSELFAQHIVTIVHHVK[136.11].E "sp|Q9Y2W1|TR150_HUMAN,tr|A0A3B3ITZ9|A0A3B3ITZ9_HUMAN" 2 2049.1251 2.57 38904 24534 4 2049.126659 513.2886 Thyroid hormone receptor-associated protein 3 OS=Homo sapiens OX=9606 GN=THRAP3 PE=1 SV=2 6.78 3782.8 - 500009 - - - 0.7633 - 2.639 0.428 - 126.3 1 2 0 0.0016 18 0 0 0 9.76E+06 3.80E+06 - - - 3.2833 1 221125_WJC_METTL3_EV_vs_WT_F03.24537.24537.3 1.62E-07 15/68 R.EGNDLYHEMIESGVINLK[136.11].D "sp|P06576|ATPB_HUMAN,tr|F8W079|F8W079_HUMAN,tr|H0YI37|H0YI37_HUMAN,tr|F8W0P7|F8W0P7_HUMAN,tr|H0YH81|H0YH81_HUMAN" 5 2068.0027 1.65 38905 24537 3 2067.999351 690.3415 "ATP synthase subunit beta, mitochondrial OS=Homo sapiens OX=9606 GN=ATP5F1B PE=1 SV=3" 4.4 3783.2 - 1.17E+07 - - - -1.5982 - 2.678 0.61 - 282.1 1 2 0 -0.0033 18 0 0 0 9.53E+07 5.77E+07 - - - 7.7929 1 221125_WJC_METTL3_EV_vs_WT_F03.24540.24540.3 5.37E-10 32/104 K.VLYDAEISQIHQSVTDTNVILSMDNSR.N sp|P35908|K22E_HUMAN 1 3047.487 999 38908 24540 3 3047.489567 1016.8363 "Keratin, type II cytoskeletal 2 epidermal OS=Homo sapiens OX=9606 GN=KRT2 PE=1 SV=2" 4.22 3783.4 - 5.86E+06 - - - 0.8489 - 5.19 0.696 - 825.6 1 2 0 0.0026 27 0 0 0 1.76E+08 0.00E+00 - - - 10.0875 1 221125_WJC_METTL3_EV_vs_WT_F03.24541.24541.3 1.54E-07 17/64 R.TQLEELEDELQATEDAK[136.11].L "sp|P35580|MYH10_HUMAN,sp|P35749|MYH11_HUMAN,sp|P35579|MYH9_HUMAN" 3 1968.9255 1.14 38909 24541 3 1968.925607 657.3158 Myosin-10 OS=Homo sapiens OX=9606 GN=MYH10 PE=1 SV=3 3.71 3783.4 - 5.69E+06 - - - 0.0488 - 3.302 0.509 - 389.2 1 2 0 0.0001 17 0 0 0 7.63E+07 6.71E+07 - - - 7.2326 1 221125_WJC_METTL3_EV_vs_WT_F03.24542.24542.3 3.92E-05 17/64 R.TQLEELEDELQATEDAK.L "sp|P35580|MYH10_HUMAN,sp|P35749|MYH11_HUMAN,sp|P35579|MYH9_HUMAN" 3 1960.9113 1.14 38910 24542 3 1960.910525 654.6444 Myosin-10 OS=Homo sapiens OX=9606 GN=MYH10 PE=1 SV=3 3.71 3783.5 - 5.06E+06 - - - -0.4008 - 3.674 0.592 - 365 1 2 0 -0.0008 17 0 0 0 7.63E+07 6.71E+07 - - - 8.4274 0.9999 221125_WJC_METTL3_EV_vs_WT_F03.24543.24543.2 1.54E-06 13/20 R.SVIEDVINDVR.D "sp|P52655|TF2AA_HUMAN,tr|J3KNC0|J3KNC0_HUMAN" 2 1257.6565 2.65 38911 24543 2 1257.655335 629.8355 Transcription initiation factor IIA subunit 1 OS=Homo sapiens OX=9606 GN=GTF2A1 PE=1 SV=1 4.03 3783.6 - 4.68E+06 - - - -0.9112 - 2.491 0.529 - 786.4 1 2 0 -0.0011 11 0 0 0 2.00E+07 7.55E+06 - - - 5.4169 1 221125_WJC_METTL3_EV_vs_WT_F03.24544.24544.4 4.32E-05 17/156 K.VLYDAEISQIHQSVTDTNVILSMDNSR.N sp|P35908|K22E_HUMAN 1 3047.487 97.81 38912 24544 4 3047.488715 762.879 "Keratin, type II cytoskeletal 2 epidermal OS=Homo sapiens OX=9606 GN=KRT2 PE=1 SV=2" 4.22 3783.7 - 4.27E+06 - - - 0.5693 - 2.6 0.486 - 97.6 1 2 0 0.0017 27 0 0 0 8.80E+07 9.00E+05 - - - 3.7546 1 221125_WJC_METTL3_EV_vs_WT_F03.24546.24546.3 6.12E-05 17/64 R.TQLPYEYYSLPFC[160.03]QPSK.L "sp|Q92544|TM9S4_HUMAN,tr|F2Z2L1|F2Z2L1_HUMAN,tr|A0A0C4DFM1|A0A0C4DFM1_HUMAN,tr|F8WCN2|F8WCN2_HUMAN" 4 2119.9925 1.29 38914 24546 3 2119.993479 707.6714 Transmembrane 9 superfamily member 4 OS=Homo sapiens OX=9606 GN=TM9SF4 PE=1 SV=2 5.66 3783.9 - 2.32E+06 - - - 0.4717 - 2.988 0.515 - 350 1 2 0 0.001 17 0 0 0 2.24E+07 1.74E+07 - - - 7.0468 1 221125_WJC_METTL3_EV_vs_WT_F03.24548.24548.3 1.11E-05 18/68 K.LQVELDNVTGLLSQSDSK[136.11].S sp|P35579|MYH9_HUMAN 1 1953.0146 1.02 38916 24548 3 1953.011532 652.0121 Myosin-9 OS=Homo sapiens OX=9606 GN=MYH9 PE=1 SV=4 4.03 3784.2 - 1.80E+06 - - - -1.5714 - 3.369 0.514 - 464.8 1 2 0 -0.0031 18 0 0 0 3.45E+07 3.38E+07 - - - 7.2943 0.9999 221125_WJC_METTL3_EV_vs_WT_F03.24550.24550.3 5.92E-07 13/44 K.ADTLTDEINFLR.A "sp|P48668|K2C6C_HUMAN,sp|P04259|K2C6B_HUMAN,sp|P02538|K2C6A_HUMAN" 3 1406.7042 75.56 38918 24550 3 1406.703391 469.9087 "Keratin, type II cytoskeletal 6C OS=Homo sapiens OX=9606 GN=KRT6C PE=1 SV=3" 4.03 3784.4 - 1.75E+06 - - - -0.546 - 2.549 0.422 - 290.6 1 2 0 -0.0008 12 0 0 0 8.29E+06 1.10E+05 - - - 5.8383 0.9853 221125_WJC_METTL3_EV_vs_WT_F03.24553.24553.2 0.00049 14/28 R.QDQIQQVVNHGLVPF.L "sp|P52292|IMA1_HUMAN,tr|A0A7I2V3Z3|A0A7I2V3Z3_HUMAN,tr|A0A7I2YQE1|A0A7I2YQE1_HUMAN,tr|A0A7I2V487|A0A7I2V487_HUMAN,tr|A0A7I2V351|A0A7I2V351_HUMAN" 5 1720.8897 - 38921 24553 2 1720.891798 861.4521 Importin subunit alpha-1 OS=Homo sapiens OX=9606 GN=KPNA2 PE=1 SV=1 5.08 3784.7 - 1.55E+06 - - - 1.2372 - 2.316 0.438 - 287.2 1 1 0 0.0021 15 0 0 0 - - - - - 4.3402 1 221125_WJC_METTL3_EV_vs_WT_F03.24554.24554.3 1.75E-07 16/84 K.MIINEELMASLDQPTQTVVMHR.T "sp|Q99613|EIF3C_HUMAN,sp|B5ME19|EIFCL_HUMAN" 2 2555.2546 1.34 38922 24554 3 2555.25782 852.7588 Eukaryotic translation initiation factor 3 subunit C OS=Homo sapiens OX=9606 GN=EIF3C PE=1 SV=1 4.65 3784.9 - 1.35E+06 - - - 1.2598 - 3.45 0.541 - 166.4 1 2 0 0.0032 22 0 0 0 5.24E+06 3.90E+06 - - - 7.5067 1 221125_WJC_METTL3_EV_vs_WT_F03.24555.24555.2 1.28E-08 16/32 R.TQLPYEYYSLPFC[160.03]QPSK.L "sp|Q92544|TM9S4_HUMAN,tr|F2Z2L1|F2Z2L1_HUMAN,tr|A0A0C4DFM1|A0A0C4DFM1_HUMAN,tr|F8WCN2|F8WCN2_HUMAN" 4 2119.9925 1.39 38923 24555 2 2119.996608 1061.0035 Transmembrane 9 superfamily member 4 OS=Homo sapiens OX=9606 GN=TM9SF4 PE=1 SV=2 5.66 3785 - 1.12E+06 - - - 1.9476 - 2.95 0.656 - 536.1 1 2 0 0.0041 17 0 0 0 8.13E+06 5.85E+06 - - - 6.5446 0.9999 221125_WJC_METTL3_EV_vs_WT_F03.24556.24556.3 5.35E-06 16/52 R.AALSEMVEYITHNR[166.11].N "sp|Q13362|2A5G_HUMAN,tr|G3V2U3|G3V2U3_HUMAN,tr|Q96B13|Q96B13_HUMAN,tr|H0YJ75|H0YJ75_HUMAN" 4 1642.8013 0.74 38924 24556 3 1642.797069 548.6077 Serine\threonine-protein phosphatase 2A 56 kDa regulatory subunit gamma isoform OS=Homo sapiens OX=9606 GN=PPP2R5C PE=1 SV=3 5.4 3785.1 - 727568 - - - -2.5517 - 2.385 0.513 - 226.2 1 2 0 -0.0042 14 0 0 0 2.63E+06 3.56E+06 - - - 6.5682 1 221125_WJC_METTL3_EV_vs_WT_F03.24558.24558.3 7.07E-05 15/56 R.DYLHLPPEIVPATLR[166.11].R "sp|P46783|RS10_HUMAN,tr|A0A2R8Y6L3|A0A2R8Y6L3_HUMAN,tr|F6U211|F6U211_HUMAN,tr|A0A1W2PQS6|A0A1W2PQS6_HUMAN,tr|A0A2R8YFH6|A0A2R8YFH6_HUMAN,tr|A0A2R8Y7H1|A0A2R8Y7H1_HUMAN,tr|S4R435|S4R435_HUMAN" 7 1742.9595 1.42 38925 24558 3 1742.958421 581.9938 40S ribosomal protein S10 OS=Homo sapiens OX=9606 GN=RPS10 PE=1 SV=1 5.32 3785.4 - 2.19E+06 - - - -0.6053 - 2.562 0.476 - 227.3 1 2 0 -0.0011 15 0 0 0 4.90E+07 3.44E+07 - - - 6.3015 1 221125_WJC_METTL3_EV_vs_WT_F03.24560.24560.2 4.84E-09 18/34 K.LQVELDNVTGLLSQSDSK[136.11].S sp|P35579|MYH9_HUMAN 1 1953.0146 1.19 38927 24560 2 1953.012887 977.5146 Myosin-9 OS=Homo sapiens OX=9606 GN=MYH9 PE=1 SV=4 4.03 3785.6 - 1.11E+07 - - - -0.8776 - 3.516 0.577 - 721 1 2 0 -0.0017 18 0 0 0 3.97E+07 3.35E+07 - - - 6.3934 1 221125_WJC_METTL3_EV_vs_WT_F03.24561.24561.2 3.59E-11 20/34 K.LQVELDNVTGLLSQSDSK.S sp|P35579|MYH9_HUMAN 1 1945.0004 1.19 38928 24561 2 1945.002265 973.5075 Myosin-9 OS=Homo sapiens OX=9606 GN=MYH9 PE=1 SV=4 4.03 3785.6 - 9.28E+06 - - - 0.9584 - 3.949 0.655 - 987.3 1 2 0 0.0019 18 0 0 0 3.97E+07 3.35E+07 - - - 7.255 1 221125_WJC_METTL3_EV_vs_WT_F03.24562.24562.2 4.61E-12 20/32 R.TQLEELEDELQATEDAK.L "sp|P35580|MYH10_HUMAN,sp|P35749|MYH11_HUMAN,sp|P35579|MYH9_HUMAN" 3 1960.9113 1.32 38929 24562 2 1960.910639 981.4629 Myosin-10 OS=Homo sapiens OX=9606 GN=MYH10 PE=1 SV=3 3.71 3785.7 - 8.23E+06 - - - -0.3427 - 4.082 0.721 - 1056.1 1 2 0 -0.0007 17 0 0 0 4.53E+07 3.44E+07 - - - 7.8243 1 221125_WJC_METTL3_EV_vs_WT_F03.24563.24563.2 4.44E-11 18/32 R.TQLEELEDELQATEDAK[136.11].L "sp|P35580|MYH10_HUMAN,sp|P35749|MYH11_HUMAN,sp|P35579|MYH9_HUMAN" 3 1968.9255 1.32 38930 24563 2 1968.923271 985.47 Myosin-10 OS=Homo sapiens OX=9606 GN=MYH10 PE=1 SV=3 3.71 3785.7 - 8.10E+06 - - - -1.1377 - 3.786 0.626 - 620.8 1 2 0 -0.0022 17 0 0 0 4.53E+07 3.44E+07 - - - 6.937 1 221125_WJC_METTL3_EV_vs_WT_F03.24565.24565.2 4.13E-06 18/26 R.TESDDLHTFLLEIK.E "sp|P35658|NU214_HUMAN,tr|A0A0A0MSW3|A0A0A0MSW3_HUMAN,tr|A0A494BZU9|A0A494BZU9_HUMAN,tr|A0A494C1F2|A0A494C1F2_HUMAN" 4 1659.8356 3 38932 24565 2 1659.833992 830.9251 Nuclear pore complex protein Nup214 OS=Homo sapiens OX=9606 GN=NUP214 PE=1 SV=2 4.31 3786 - 3.43E+06 - - - -0.9489 - 3.849 0.539 - 1326.1 1 2 0 -0.0016 14 0 0 0 1.38E+07 4.59E+06 - - - 6.4038 1 221125_WJC_METTL3_EV_vs_WT_F03.24566.24566.3 1.37E-12 20/56 R.EGSEEDLDALEHMFR.Q sp|P31944|CASPE_HUMAN 1 1776.7625 999 38933 24566 3 1776.762148 593.2614 Caspase-14 OS=Homo sapiens OX=9606 GN=CASP14 PE=1 SV=2 4.08 3786 - 3.21E+06 - - - -0.1863 - 3.987 0.692 - 896.8 1 2 0 -0.0003 15 0 0 0 3.72E+07 0.00E+00 - - - 9.8639 1 221125_WJC_METTL3_EV_vs_WT_F03.24568.24568.2 6.63E-05 20/34 K.SEGALELADVSNELPGLK[136.11].W sp|Q08J23|NSUN2_HUMAN 1 1848.956 1.04 38935 24568 2 1848.951745 925.4853 RNA cytosine C(5)-methyltransferase NSUN2 OS=Homo sapiens OX=9606 GN=NSUN2 PE=1 SV=2 4 3786.3 - 1.90E+06 - - - -2.3143 - 3.747 0.609 - 842.6 1 2 0 -0.0043 18 0 0 0 1.66E+07 1.59E+07 - - - 6.7854 1 221125_WJC_METTL3_EV_vs_WT_F03.24569.24569.2 3.02E-07 19/34 K.SEGALELADVSNELPGLK.W sp|Q08J23|NSUN2_HUMAN 1 1840.9418 1.04 38936 24569 2 1840.942552 921.4782 RNA cytosine C(5)-methyltransferase NSUN2 OS=Homo sapiens OX=9606 GN=NSUN2 PE=1 SV=2 4 3786.4 - 1.58E+06 - - - 0.3954 - 3.735 0.602 - 766.7 1 2 0 0.0007 18 0 0 0 1.66E+07 1.59E+07 - - - 6.7269 1 221125_WJC_METTL3_EV_vs_WT_F03.24570.24570.3 4.60E-14 19/84 K.MIINEELMASLDQPTQTVVMHR[166.11].T "sp|Q99613|EIF3C_HUMAN,sp|B5ME19|EIFCL_HUMAN" 2 2565.2629 1.34 38937 24570 3 2565.257956 856.0949 Eukaryotic translation initiation factor 3 subunit C OS=Homo sapiens OX=9606 GN=EIF3C PE=1 SV=1 4.65 3786.5 - 1.31E+06 - - - -1.916 - 3.521 0.652 - 330.6 1 2 0 -0.0049 22 0 0 0 5.24E+06 3.90E+06 - - - 8.7921 1 221125_WJC_METTL3_EV_vs_WT_F03.24574.24574.2 1.70E-08 18/34 R.TNLIVNYLPQNMTQDELR[166.11].S "sp|Q15717|ELAV1_HUMAN,tr|M0QZR9|M0QZR9_HUMAN" 2 2171.092 1.31 38941 24574 2 2171.092286 1086.5533 ELAV-like protein 1 OS=Homo sapiens OX=9606 GN=ELAVL1 PE=1 SV=2 4.37 3787.1 - 643360 - - - 0.1207 - 3.559 0.535 - 558.8 1 2 0 0.0003 18 0 0 0 2.30E+07 1.76E+07 - - - 6.1135 1 221125_WJC_METTL3_EV_vs_WT_F03.24580.24580.2 8.34E-18 25/52 K.VLYDAEISQIHQSVTDTNVILSMDNSR.N sp|P35908|K22E_HUMAN 1 3047.487 999 38945 24580 2 3047.487186 1524.7508 "Keratin, type II cytoskeletal 2 epidermal OS=Homo sapiens OX=9606 GN=KRT2 PE=1 SV=2" 4.22 3787.8 - 2.36E+06 - - - 0.0676 - 4.817 0.761 - 1002.5 1 2 0 0.0002 27 0 0 0 8.89E+06 0.00E+00 - - - 8.5269 1 221125_WJC_METTL3_EV_vs_WT_F03.24581.24581.2 1.68E-10 18/34 R.TNLIVNYLPQNMTQDELR.S "sp|Q15717|ELAV1_HUMAN,tr|M0QZR9|M0QZR9_HUMAN" 2 2161.0838 1.31 38946 24581 2 2161.083768 1081.5492 ELAV-like protein 1 OS=Homo sapiens OX=9606 GN=ELAVL1 PE=1 SV=2 4.37 3787.9 - 2.21E+06 - - - 0.0065 - 3.921 0.653 - 715 1 2 0 0 18 0 0 0 2.30E+07 1.76E+07 - - - 7.2233 0.9995 221125_WJC_METTL3_EV_vs_WT_F03.24582.24582.2 5.57E-06 26-Dec K.DATNVAAAFEEAVR[166.11].R sp|P51151|RAB9A_HUMAN 1 1472.7135 0.51 38947 24582 2 1472.717384 737.364 Ras-related protein Rab-9A OS=Homo sapiens OX=9606 GN=RAB9A PE=1 SV=1 4.14 3788 - 1.62E+06 - - - 2.6427 - 2.386 0.448 - 425.2 1 2 0 0.0039 14 0 0 0 6.13E+06 1.20E+07 - - - 4.531 1 221125_WJC_METTL3_EV_vs_WT_F03.24584.24584.3 3.19E-10 28/108 K.SLGPAAPIIDSPYGDPIDPEDAPESITR.A sp|Q9H0L4|CSTFT_HUMAN 1 2892.4029 8.12 38949 24584 3 2892.409227 965.1416 Cleavage stimulation factor subunit 2 tau variant OS=Homo sapiens OX=9606 GN=CSTF2T PE=1 SV=1 3.66 3788.3 - 1.13E+06 - - - 2.1878 - 4.016 0.615 - 521.5 1 2 0 0.0063 28 0 0 0 1.42E+07 1.75E+06 - - - 8.5934 1 221125_WJC_METTL3_EV_vs_WT_F03.24585.24585.3 7.38E-10 17/68 K.SEGALELADVSNELPGLK[136.11].W sp|Q08J23|NSUN2_HUMAN 1 1848.956 1.3 38950 24585 3 1848.953651 617.326 RNA cytosine C(5)-methyltransferase NSUN2 OS=Homo sapiens OX=9606 GN=NSUN2 PE=1 SV=2 4 3788.4 - 834330 - - - -1.2834 - 2.569 0.574 - 237.7 1 2 0 -0.0024 18 0 0 0 8.97E+06 6.88E+06 - - - 7.2883 1 221125_WJC_METTL3_EV_vs_WT_F03.24586.24586.3 1.05E-06 18/52 K.QMEQISQFLQAAER[166.11].Y "sp|P37802|TAGL2_HUMAN,tr|X6RJP6|X6RJP6_HUMAN" 2 1687.8227 1.52 38951 24586 3 1687.823593 563.6149 Transgelin-2 OS=Homo sapiens OX=9606 GN=TAGLN2 PE=1 SV=3 4.53 3788.5 - 583010 - - - 0.5143 - 3.149 0.534 - 382.7 1 2 0 0.0009 14 0 0 0 5.40E+06 3.56E+06 - - - 7.5417 0.9994 221125_WJC_METTL3_EV_vs_WT_F03.24588.24588.2 1.96E-09 13/28 R.EGSEEDLDALEHMFR.Q sp|P31944|CASPE_HUMAN 1 1776.7625 -1 38953 24588 2 1776.756866 889.3885 Caspase-14 OS=Homo sapiens OX=9606 GN=CASP14 PE=1 SV=2 4.08 3788.8 - 447269 - - - -3.1591 - 2.825 0.457 - 726.5 1 2 0 -0.0056 15 0 0 0 0.00E+00 0.00E+00 - - - 4.9679 1 221125_WJC_METTL3_EV_vs_WT_F03.24596.24596.3 1.17E-09 16/56 R.DYLHLPPEIVPATLR.R "sp|P46783|RS10_HUMAN,tr|A0A2R8Y6L3|A0A2R8Y6L3_HUMAN,tr|F6U211|F6U211_HUMAN,tr|A0A1W2PQS6|A0A1W2PQS6_HUMAN,tr|A0A2R8YFH6|A0A2R8YFH6_HUMAN,tr|A0A2R8Y7H1|A0A2R8Y7H1_HUMAN,tr|S4R435|S4R435_HUMAN" 7 1732.9512 1.48 38959 24596 3 1732.951793 578.6577 40S ribosomal protein S10 OS=Homo sapiens OX=9606 GN=RPS10 PE=1 SV=1 5.32 3789.6 - 2.66E+06 - - - 0.3387 - 3.21 0.615 - 238.2 1 2 0 0.0006 15 0 0 0 1.94E+07 1.32E+07 - - - 8.4397 1 221125_WJC_METTL3_EV_vs_WT_F03.24598.24598.3 2.81E-06 13/44 K.GHILELLTEVTR.R sp|P31944|CASPE_HUMAN 1 1379.7773 32.58 38961 24598 3 1379.776288 460.933 Caspase-14 OS=Homo sapiens OX=9606 GN=CASP14 PE=1 SV=2 5.4 3789.7 - 1.97E+06 - - - -0.7081 - 2.555 0.489 - 395 1 2 0 -0.001 12 0 0 0 4.17E+06 1.28E+05 - - - 6.5917 0.9988 221125_WJC_METTL3_EV_vs_WT_F03.24599.24599.3 1.65E-06 21/60 A.SLNLEETLSTLEYAHR.A "sp|P52732|KIF11_HUMAN,tr|A0A7I2YQY4|A0A7I2YQY4_HUMAN,tr|A0A7I2V3A9|A0A7I2V3A9_HUMAN,tr|A0A7I2V3V3|A0A7I2V3V3_HUMAN" 4 1874.9374 4.92 38962 24599 3 1874.93706 625.9864 Kinesin-like protein KIF11 OS=Homo sapiens OX=9606 GN=KIF11 PE=1 SV=2 4.75 3789.9 - 1.82E+06 - - - -0.1851 - 3.446 0.558 - 451.2 1 1 0 -0.0003 16 0 0 0 6.99E+07 1.42E+07 - - - 7.9356 1 221125_WJC_METTL3_EV_vs_WT_F03.24601.24601.3 2.49E-10 23/112 R.IMLTTPQQIQLNPLQPVPVVKPAVLPGTK.A "sp|O00268|TAF4_HUMAN,tr|V9GY14|V9GY14_HUMAN,tr|A0A0G2JRY5|A0A0G2JRY5_HUMAN" 3 3119.8144 2.51 38964 24601 3 3119.81015 1040.9454 Transcription initiation factor TFIID subunit 4 OS=Homo sapiens OX=9606 GN=TAF4 PE=1 SV=2 10 3790.1 - 1.68E+06 - - - -1.378 - 3.669 0.761 - 379.1 1 2 0 -0.0043 29 0 0 0 6.67E+06 2.66E+06 - - - 10.0138 0.9997 221125_WJC_METTL3_EV_vs_WT_F03.24604.24604.3 7.35E-05 17/44 K.DFINFISDKEWK.S sp|Q9H3N1|TMX1_HUMAN 1 1540.7562 0.98 38967 24604 3 1540.756174 514.5927 Thioredoxin-related transmembrane protein 1 OS=Homo sapiens OX=9606 GN=TMX1 PE=1 SV=1 4.56 3790.5 - 1.30E+06 - - - -0.0136 - 2.943 0.369 - 279.3 1 2 1 0 12 0 0 0 1.16E+07 1.18E+07 - - - 5.646 0.9999 221125_WJC_METTL3_EV_vs_WT_F03.24610.24610.3 0.000306 Dec-48 R.LQLLSNLFHGMDK[136.11].N "sp|Q7L2H7|EIF3M_HUMAN,tr|E9PN86|E9PN86_HUMAN,tr|J3KNJ2|J3KNJ2_HUMAN" 3 1522.8057 0.96 38973 24610 3 1522.808193 508.6092 Eukaryotic translation initiation factor 3 subunit M OS=Homo sapiens OX=9606 GN=EIF3M PE=1 SV=1 6.74 3791.3 - 385069 - - - 1.6141 - 2.487 0.415 - 240.4 1 2 0 0.0025 13 0 0 0 2.33E+06 2.43E+06 - - - 5.6364 0.9998 221125_WJC_METTL3_EV_vs_WT_F03.24612.24612.2 1.71E-05 22-Sep R.LFPPQWIC[160.03]C[160.03]DIR[166.11].Y sp|Q86U44|MTA70_HUMAN 1 1613.7722 0.001 38974 24612 2 1613.771489 807.8934 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 5.82 3791.5 - 3.64E+06 - - - -0.4468 - 1.778 0.465 - 239.7 1 2 0 -0.0007 12 0 0 0 0.00E+00 2.54E+07 - - - 3.9895 1 221125_WJC_METTL3_EV_vs_WT_F03.24614.24614.4 5.44E-11 27/114 K.TLSYLLPAIVHINHQPFLER.G "sp|P17844|DDX5_HUMAN,tr|A0A7I2V5F5|A0A7I2V5F5_HUMAN,tr|J3QRN5|J3QRN5_HUMAN,tr|A0A7I2V507|A0A7I2V507_HUMAN,tr|J3KTA4|J3KTA4_HUMAN,tr|A0A0G2JLI4|A0A0G2JLI4_HUMAN,tr|A0A7I2V2S0|A0A7I2V2S0_HUMAN,tr|J3QRQ7|J3QRQ7_HUMAN" 8 2360.3005 1.81 38976 24614 4 2360.303818 591.0824 Probable ATP-dependent RNA helicase DDX5 OS=Homo sapiens OX=9606 GN=DDX5 PE=1 SV=1 6.61 3791.7 - 7.41E+06 - - - 1.4113 - 3.451 0.627 - 388.7 1 2 0 0.0033 20 0 0 0 1.04E+08 5.73E+07 - - - 5.0966 1 221125_WJC_METTL3_EV_vs_WT_F03.24615.24615.4 2.53E-06 24/114 K.TLSYLLPAIVHINHQPFLER[166.11].G "sp|P17844|DDX5_HUMAN,tr|A0A7I2V5F5|A0A7I2V5F5_HUMAN,tr|J3QRN5|J3QRN5_HUMAN,tr|A0A7I2V507|A0A7I2V507_HUMAN,tr|J3KTA4|J3KTA4_HUMAN,tr|A0A0G2JLI4|A0A0G2JLI4_HUMAN,tr|A0A7I2V2S0|A0A7I2V2S0_HUMAN,tr|J3QRQ7|J3QRQ7_HUMAN" 8 2370.3088 1.8 38977 24615 4 2370.312005 593.5845 Probable ATP-dependent RNA helicase DDX5 OS=Homo sapiens OX=9606 GN=DDX5 PE=1 SV=1 6.61 3791.7 - 4.08E+06 - - - 1.3703 - 3.513 0.639 - 312.3 1 2 0 0.0032 20 0 0 0 9.45E+07 5.26E+07 - - - 5.207 1 221125_WJC_METTL3_EV_vs_WT_F03.24616.24616.3 1.92E-09 19/64 R.ELESQISELQEDLESER.A sp|P35579|MYH9_HUMAN 1 2032.9437 1.33 38978 24616 3 2032.946745 678.6552 Myosin-9 OS=Homo sapiens OX=9606 GN=MYH9 PE=1 SV=4 3.77 3791.8 - 2.46E+06 - - - 1.5106 - 3.457 0.593 - 594.2 1 2 0 0.0031 17 0 0 0 3.15E+07 2.38E+07 - - - 8.2841 0.9998 221125_WJC_METTL3_EV_vs_WT_F03.24617.24617.3 0.00332 15/44 K.DFINFISDK[136.11]EWK[136.11].S sp|Q9H3N1|TMX1_HUMAN 1 1556.7846 0.9 38979 24617 3 1556.786317 519.9355 Thioredoxin-related transmembrane protein 1 OS=Homo sapiens OX=9606 GN=TMX1 PE=1 SV=1 4.56 3791.9 - 2.37E+06 - - - 1.1061 - 2.849 0.421 - 224.8 1 2 1 0.0017 12 0 0 0 1.16E+07 1.29E+07 - - - 6.1353 1 221125_WJC_METTL3_EV_vs_WT_F03.24618.24618.3 2.30E-10 24/80 K.IREYFGGFGEVESIELPMDNK.T "sp|Q14103|HNRPD_HUMAN,tr|H0Y8G5|H0Y8G5_HUMAN,tr|D6RAF8|D6RAF8_HUMAN,tr|H0YA96|H0YA96_HUMAN" 4 2429.1573 0.61 38980 24618 3 2429.160363 810.7264 Heterogeneous nuclear ribonucleoprotein D0 OS=Homo sapiens OX=9606 GN=HNRNPD PE=1 SV=1 4.25 3791.9 - 2.09E+06 - - - 1.256 - 4.32 0.624 - 496.8 1 2 1 0.0031 21 0 0 0 2.44E+07 3.99E+07 - - - 9.0042 0.9999 221125_WJC_METTL3_EV_vs_WT_F03.24619.24619.3 5.82E-08 22/68 R.GGPNIITLADIVK[136.11]DPVSR[166.11].T "sp|P68400|CSK21_HUMAN,sp|Q8NEV1|CSK23_HUMAN,tr|V9GYA2|V9GYA2_HUMAN,tr|A0A2R8YEW1|A0A2R8YEW1_HUMAN,tr|A0A2R8Y4D6|A0A2R8Y4D6_HUMAN,tr|A0A2R8YD58|A0A2R8YD58_HUMAN,tr|A0A2R8YF43|A0A2R8YF43_HUMAN,tr|A0A2R8Y5A0|A0A2R8Y5A0_HUMAN,tr|A0A2R8Y4H0|A0A2R8Y4H0_HUMAN,tr|E7EU96|E7EU96_HUMAN" 10 1882.0643 1.16 38981 24619 3 1882.067124 628.362 Casein kinase II subunit alpha OS=Homo sapiens OX=9606 GN=CSNK2A1 PE=1 SV=1 5.96 3792 - 1.96E+06 - - - 1.51 - 3.393 0.598 - 563 1 2 1 0.0028 18 0 0 0 2.08E+07 1.80E+07 - - - 8.2485 0.9999 221125_WJC_METTL3_EV_vs_WT_F03.24621.24621.3 1.05E-06 20/68 R.GGPNIITLADIVKDPVSR.T "sp|P68400|CSK21_HUMAN,sp|Q8NEV1|CSK23_HUMAN,tr|V9GYA2|V9GYA2_HUMAN,tr|A0A2R8YEW1|A0A2R8YEW1_HUMAN,tr|A0A2R8Y4D6|A0A2R8Y4D6_HUMAN,tr|A0A2R8YD58|A0A2R8YD58_HUMAN,tr|A0A2R8YF43|A0A2R8YF43_HUMAN,tr|A0A2R8Y5A0|A0A2R8Y5A0_HUMAN,tr|A0A2R8Y4H0|A0A2R8Y4H0_HUMAN,tr|E7EU96|E7EU96_HUMAN" 10 1864.0418 1.16 38983 24621 3 1864.045126 622.3545 Casein kinase II subunit alpha OS=Homo sapiens OX=9606 GN=CSNK2A1 PE=1 SV=1 5.96 3792.2 - 1.60E+06 - - - 1.7779 - 3.276 0.556 - 371.1 1 2 1 0.0033 18 0 0 0 2.08E+07 1.80E+07 - - - 7.6927 1 221125_WJC_METTL3_EV_vs_WT_F03.24622.24622.3 5.35E-08 19/56 K.GSIFVVFDSIESAKK.F "sp|P05455|LA_HUMAN,tr|E9PGX9|E9PGX9_HUMAN,tr|E7ERC4|E7ERC4_HUMAN" 3 1625.8665 0.88 38984 24622 3 1625.869199 542.9628 Lupus La protein OS=Homo sapiens OX=9606 GN=SSB PE=1 SV=2 6.07 3792.3 - 1.41E+06 - - - 1.676 - 2.96 0.557 - 455.8 1 2 0 0.0027 15 0 0 0 7.96E+06 9.00E+06 - - - 7.5809 1 221125_WJC_METTL3_EV_vs_WT_F03.24623.24623.2 1.99E-10 28-Dec R.FTPGTFTNQIQAAFR[166.11].E "sp|P08865|RSSA_HUMAN,tr|C9J9K3|C9J9K3_HUMAN,tr|A0A0C4DG17|A0A0C4DG17_HUMAN" 3 1707.8608 0.56 38985 24623 2 1707.859943 854.9377 40S ribosomal protein SA OS=Homo sapiens OX=9606 GN=RPSA PE=1 SV=4 9.75 3792.4 - 1.08E+06 - - - -0.5164 - 2.913 0.597 - 513.4 1 2 0 -0.0009 15 0 0 0 3.65E+06 6.57E+06 - - - 6.0788 0.9966 221125_WJC_METTL3_EV_vs_WT_F03.24624.24624.3 0.0619 14/48 R.KFVFFNIPQIQYK.N "sp|P82663|RT25_HUMAN,tr|E7EPW2|E7EPW2_HUMAN" 2 1670.9184 1.81 38986 24624 3 1670.92216 557.9801 "28S ribosomal protein S25, mitochondrial OS=Homo sapiens OX=9606 GN=MRPS25 PE=1 SV=1" 9.7 3792.5 - 1.06E+06 - - - 2.2203 - 1.989 0.234 - 260.3 1 2 0 0.0037 13 0 0 0 6.46E+06 3.56E+06 - - - 3.0122 1 221125_WJC_METTL3_EV_vs_WT_F03.24625.24625.3 3.14E-15 28/116 K.YTLPPGVDPTQVSSSLSPEGTLTVEAPMPK.L "sp|P04792|HSPB1_HUMAN,tr|A0A6Q8PGK1|A0A6Q8PGK1_HUMAN" 2 3097.5529 6.68 38987 24625 3 3097.555934 1033.5249 Heat shock protein beta-1 OS=Homo sapiens OX=9606 GN=HSPB1 PE=1 SV=2 4.14 3792.6 - 1.02E+06 - - - 0.9685 - 4.678 0.653 - 675.4 1 2 0 0.003 30 0 0 0 1.13E+07 1.70E+06 - - - 9.3691 0.9999 221125_WJC_METTL3_EV_vs_WT_F03.24628.24628.3 7.66E-05 14/48 R.K[136.11]FVFFNIPQIQYK[136.11].N "sp|P82663|RT25_HUMAN,tr|E7EPW2|E7EPW2_HUMAN" 2 1686.9469 18.43 38990 24628 3 1686.949751 563.3229 "28S ribosomal protein S25, mitochondrial OS=Homo sapiens OX=9606 GN=MRPS25 PE=1 SV=1" 9.7 3793 - 886248 - - - 1.7197 - 2.458 0.45 - 250.6 1 2 0 0.0029 13 0 0 0 6.56E+07 3.56E+06 - - - 5.9946 1 221125_WJC_METTL3_EV_vs_WT_F03.24629.24629.2 9.31E-08 28-Dec K.FDVQFPENNWINPDK[136.11].L sp|O60884|DNJA2_HUMAN 1 1869.8777 0.42 38991 24629 2 1869.878321 935.9461 DnaJ homolog subfamily A member 2 OS=Homo sapiens OX=9606 GN=DNAJA2 PE=1 SV=1 4.03 3793.1 - 745079 - - - 0.3246 - 2.465 0.608 - 462.9 1 2 0 0.0006 15 0 0 0 2.61E+06 6.24E+06 - - - 5.7496 1 221125_WJC_METTL3_EV_vs_WT_F03.24631.24631.2 2.13E-08 14/22 K.GHILELLTEVTR.R sp|P31944|CASPE_HUMAN 1 1379.7773 999 38993 24631 2 1379.781975 690.8959 Caspase-14 OS=Homo sapiens OX=9606 GN=CASP14 PE=1 SV=2 5.4 3793.4 - 661980 - - - 3.4136 - 2.754 0.595 - 565.7 1 2 0 0.0047 12 0 0 0 8.90E+06 0.00E+00 - - - 6.0997 1 221125_WJC_METTL3_EV_vs_WT_F03.24636.24636.3 1.96E-07 25/76 K.TLSYLLPAIVHINHQPFLER.G "sp|P17844|DDX5_HUMAN,tr|A0A7I2V5F5|A0A7I2V5F5_HUMAN,tr|J3QRN5|J3QRN5_HUMAN,tr|A0A7I2V507|A0A7I2V507_HUMAN,tr|J3KTA4|J3KTA4_HUMAN,tr|A0A0G2JLI4|A0A0G2JLI4_HUMAN,tr|A0A7I2V2S0|A0A7I2V2S0_HUMAN,tr|J3QRQ7|J3QRQ7_HUMAN" 8 2360.3005 1.54 38997 24636 3 2360.299955 787.7741 Probable ATP-dependent RNA helicase DDX5 OS=Homo sapiens OX=9606 GN=DDX5 PE=1 SV=1 6.61 3793.8 - 1.58E+06 - - - -0.2254 - 3.744 0.671 - 678.6 1 2 0 -0.0005 20 0 0 0 2.43E+07 1.58E+07 - - - 9.2236 1 221125_WJC_METTL3_EV_vs_WT_F03.24637.24637.3 1.65E-08 17/56 K.GSIFVVFDSIESAK[136.11]K[136.11].F "sp|P05455|LA_HUMAN,tr|E9PGX9|E9PGX9_HUMAN,tr|E7ERC4|E7ERC4_HUMAN" 3 1641.8949 0.88 38998 24637 3 1641.895759 548.3056 Lupus La protein OS=Homo sapiens OX=9606 GN=SSB PE=1 SV=2 6.07 3793.9 - 1.52E+06 - - - 0.539 - 3.089 0.653 - 332.7 1 2 0 0.0009 15 0 0 0 7.96E+06 9.00E+06 - - - 8.763 1 221125_WJC_METTL3_EV_vs_WT_F03.24639.24639.3 1.74E-15 22/96 R.LLEDGEDFNLGDALDSSNSMQTIQK.T sp|P05783|K1C18_HUMAN 1 2739.2545 24.61 39000 24639 3 2739.256546 914.0921 "Keratin, type I cytoskeletal 18 OS=Homo sapiens OX=9606 GN=KRT18 PE=1 SV=2" 3.66 3794.1 - 1.06E+06 - - - 0.7396 - 4.284 0.723 - 610.5 1 2 0 0.002 25 0 0 0 5.00E+06 2.03E+05 - - - 9.9473 1 221125_WJC_METTL3_EV_vs_WT_F03.24640.24640.3 1.05E-11 20/80 M.PGGLLLGDVAPNFEANTTVGR[166.11].L sp|P30041|PRDX6_HUMAN 1 2107.0937 -1 39001 24640 3 2107.096048 703.3719 Peroxiredoxin-6 OS=Homo sapiens OX=9606 GN=PRDX6 PE=1 SV=3 4.37 3794.2 - 935339 - - - 1.0963 - 4.216 0.62 - 660.4 1 2 0 0.0023 21 0 0 0 0.00E+00 0.00E+00 - - - 8.9014 0.9861 221125_WJC_METTL3_EV_vs_WT_F03.24641.24641.3 0.00122 13/56 R.SEQLEELFSQVGPVK[136.11].Q "sp|Q9NW13|RBM28_HUMAN,tr|C9JAA9|C9JAA9_HUMAN,tr|C9JE21|C9JE21_HUMAN" 3 1696.8763 0.65 39002 24641 3 1696.861793 566.6327 RNA-binding protein 28 OS=Homo sapiens OX=9606 GN=RBM28 PE=1 SV=3 4.25 3794.3 - 880168 - - - -8.5593 - 2.074 0.419 - 156.1 1 2 0 -0.0145 15 0 0 0 3.79E+06 5.84E+06 - - - 5.1109 1 221125_WJC_METTL3_EV_vs_WT_F03.24642.24642.3 1.28E-06 24/76 K.TLSYLLPAIVHINHQPFLER[166.11].G "sp|P17844|DDX5_HUMAN,tr|A0A7I2V5F5|A0A7I2V5F5_HUMAN,tr|J3QRN5|J3QRN5_HUMAN,tr|A0A7I2V507|A0A7I2V507_HUMAN,tr|J3KTA4|J3KTA4_HUMAN,tr|A0A0G2JLI4|A0A0G2JLI4_HUMAN,tr|A0A7I2V2S0|A0A7I2V2S0_HUMAN,tr|J3QRQ7|J3QRQ7_HUMAN" 8 2370.3088 1.54 39003 24642 3 2370.311409 791.1102 Probable ATP-dependent RNA helicase DDX5 OS=Homo sapiens OX=9606 GN=DDX5 PE=1 SV=1 6.61 3794.4 - 868234 - - - 1.1188 - 3.547 0.636 - 546.9 1 2 0 0.0027 20 0 0 0 2.43E+07 1.58E+07 - - - 8.7016 0.9999 221125_WJC_METTL3_EV_vs_WT_F03.24643.24643.3 7.30E-05 19/84 K.TLVQNNC[160.03]LTRPNIYLIPDIDLK.L sp|Q92922|SMRC1_HUMAN 1 2612.3996 2.71 39004 24643 3 2612.402171 871.8071 SWI\SNF complex subunit SMARCC1 OS=Homo sapiens OX=9606 GN=SMARCC1 PE=1 SV=3 5.62 3794.5 - 748813 - - - 0.9807 - 2.656 0.379 - 264 1 2 0 0.0026 22 0 0 0 1.64E+07 6.07E+06 - - - 5.0806 0.9997 221125_WJC_METTL3_EV_vs_WT_F03.24644.24644.3 0.000103 Oct-56 R.FTPGTFTNQIQAAFR[166.11].E "sp|P08865|RSSA_HUMAN,tr|C9J9K3|C9J9K3_HUMAN,tr|A0A0C4DG17|A0A0C4DG17_HUMAN" 3 1707.8608 0.53 39005 24644 3 1707.862647 570.2942 40S ribosomal protein SA OS=Homo sapiens OX=9606 GN=RPSA PE=1 SV=4 9.75 3794.6 - 631130 - - - 1.0668 - 2.325 0.314 - 113.7 1 2 0 0.0018 15 0 0 0 2.14E+06 4.02E+06 - - - 4.2419 0.9999 221125_WJC_METTL3_EV_vs_WT_F03.24649.24649.3 0.00197 Nov-64 R.SIFYVPDMKPSMFDVSR.E "sp|Q12931|TRAP1_HUMAN,tr|I3L0K7|I3L0K7_HUMAN,tr|I3L239|I3L239_HUMAN" 3 2017.9642 2.45 39009 24649 3 2017.964488 673.662 "Heat shock protein 75 kDa, mitochondrial OS=Homo sapiens OX=9606 GN=TRAP1 PE=1 SV=3" 5.68 3795.2 - 1.51E+06 - - - 0.1645 - 2.015 0.423 - 81.9 1 2 0 0.0003 17 0 0 0 6.18E+06 2.52E+06 - - - 5.0259 1 221125_WJC_METTL3_EV_vs_WT_F03.24653.24653.3 3.07E-05 16/64 R.ELESQISELQEDLESER[166.11].A sp|P35579|MYH9_HUMAN 1 2042.9519 1.33 39012 24653 3 2042.953761 681.9913 Myosin-9 OS=Homo sapiens OX=9606 GN=MYH9 PE=1 SV=4 3.77 3795.6 - 7.85E+06 - - - 0.8894 - 3.09 0.547 - 399.5 1 2 0 0.0018 17 0 0 0 3.15E+07 2.38E+07 - - - 7.4881 0.9989 221125_WJC_METTL3_EV_vs_WT_F03.24654.24654.3 2.26E-06 15/60 A.SLNLEETLSTLEYAHR[166.11].A "sp|P52732|KIF11_HUMAN,tr|A0A7I2YQY4|A0A7I2YQY4_HUMAN,tr|A0A7I2V3A9|A0A7I2V3A9_HUMAN,tr|A0A7I2V3V3|A0A7I2V3V3_HUMAN" 4 1884.9457 4.92 39013 24654 3 1884.945649 629.3225 Kinesin-like protein KIF11 OS=Homo sapiens OX=9606 GN=KIF11 PE=1 SV=2 4.75 3795.7 - 4.96E+06 - - - -0.0149 - 3.244 0.602 - 223.5 1 1 0 0 16 0 0 0 6.99E+07 1.42E+07 - - - 8.2712 0.9999 221125_WJC_METTL3_EV_vs_WT_F03.24655.24655.3 3.12E-08 15/64 K.VC[160.03]LQTFESTQALLEHLK.A sp|Q9UPG8|PLAL2_HUMAN 1 2016.035 0.86 39014 24655 3 2016.03949 673.0189 Zinc finger protein PLAGL2 OS=Homo sapiens OX=9606 GN=PLAGL2 PE=1 SV=1 5.4 3795.8 - 1.66E+06 - - - 2.2207 - 2.892 0.509 - 182.1 1 2 0 0.0045 17 0 0 0 4.98E+06 5.76E+06 - - - 6.8964 1 221125_WJC_METTL3_EV_vs_WT_F03.24657.24657.3 7.17E-07 Oct-64 K.VC[160.03]LQTFESTQALLEHLK[136.11].A sp|Q9UPG8|PLAL2_HUMAN 1 2024.0492 1.18 39016 24657 3 2024.052876 675.6903 Zinc finger protein PLAGL2 OS=Homo sapiens OX=9606 GN=PLAGL2 PE=1 SV=1 5.4 3796.1 - 1.35E+06 - - - 1.8097 - 2.586 0.503 - 118.1 1 2 0 0.0037 17 0 0 0 4.68E+06 3.98E+06 - - - 6.5472 1 221125_WJC_METTL3_EV_vs_WT_F03.24658.24658.3 1.29E-05 16/64 K.RIDMVPELLSSNLC[160.03]SLK.C "sp|Q9Y2L1|RRP44_HUMAN,tr|F2Z2C0|F2Z2C0_HUMAN,tr|G3V1J5|G3V1J5_HUMAN" 3 1974.0278 1.73 39017 24658 3 1974.028779 659.0165 Exosome complex exonuclease RRP44 OS=Homo sapiens OX=9606 GN=DIS3 PE=1 SV=2 6.06 3796.2 - 1.35E+06 - - - 0.4863 - 3.087 0.525 - 341.5 1 2 0 0.001 17 0 0 0 1.19E+07 6.89E+06 - - - 7.2406 0.9999 221125_WJC_METTL3_EV_vs_WT_F03.24659.24659.3 1.47E-06 Nov-56 R.SEQLEELFSQVGPVK.Q "sp|Q9NW13|RBM28_HUMAN,tr|C9JAA9|C9JAA9_HUMAN,tr|C9JE21|C9JE21_HUMAN" 3 1688.8621 0.67 39018 24659 3 1688.86539 563.9613 RNA-binding protein 28 OS=Homo sapiens OX=9606 GN=RBM28 PE=1 SV=3 4.25 3796.3 - 1.30E+06 - - - 1.938 - 2.281 0.462 - 108.3 1 2 0 0.0033 15 0 0 0 3.79E+06 5.67E+06 - - - 5.8417 0.9993 221125_WJC_METTL3_EV_vs_WT_F03.24661.24661.2 0.00276 16-Sep K.DAEDWFFSK.T "sp|Q04695|K1C17_HUMAN,tr|K7ESE1|K7ESE1_HUMAN,tr|F5GWP8|F5GWP8_HUMAN" 3 1143.4873 65.48 39020 24661 2 1143.488524 572.7509 "Keratin, type I cytoskeletal 17 OS=Homo sapiens OX=9606 GN=KRT17 PE=1 SV=2" 4.03 3796.6 - 1.16E+06 - - - 1.0792 - 1.957 0.281 - 288.8 1 2 0 0.0012 9 0 0 0 1.76E+07 2.68E+05 - - - 3.0585 0.9999 221125_WJC_METTL3_EV_vs_WT_F03.24665.24665.3 0.00155 14/48 K.VAIFTLINEINK[136.11]K[136.11].G "sp|Q9UPN9|TRI33_HUMAN,tr|H0Y612|H0Y612_HUMAN" 2 1517.9152 0.27 39024 24665 3 1517.913872 506.979 E3 ubiquitin-protein ligase TRIM33 OS=Homo sapiens OX=9606 GN=TRIM33 PE=1 SV=3 8.56 3797.1 - 655667 - - - -0.8848 - 2.655 0.366 - 220.2 1 2 0 -0.0013 13 0 0 0 6.07E+05 2.22E+06 - - - 5.2676 0.9873 221125_WJC_METTL3_EV_vs_WT_F03.24666.24666.3 0.000402 Oct-52 K.TSQLLETLNQLSTH.T "sp|Q14203|DCTN1_HUMAN,tr|A0A804CDA6|A0A804CDA6_HUMAN,tr|E7EX90|E7EX90_HUMAN,tr|A0A7P0Z4C3|A0A7P0Z4C3_HUMAN,tr|E7EWF7|E7EWF7_HUMAN" 5 1583.8155 - 39025 24666 3 1583.815212 528.9458 Dynactin subunit 1 OS=Homo sapiens OX=9606 GN=DCTN1 PE=1 SV=3 5.21 3797.2 - 644465 - - - -0.1825 - 2.105 0.402 - 107.8 1 1 0 -0.0003 14 0 0 0 - - - - - 4.9999 0.9995 221125_WJC_METTL3_EV_vs_WT_F03.24669.24669.2 4.38E-06 13/24 R.SIQFVDWC[160.03]PTGFK[136.11].V "sp|P68366|TBA4A_HUMAN,sp|P68363|TBA1B_HUMAN" 2 1591.7585 0.49 39028 24669 2 1591.763515 796.8865 Tubulin alpha-4A chain OS=Homo sapiens OX=9606 GN=TUBA4A PE=1 SV=1 5.55 3797.6 - 352183 - - - 3.182 - 2.409 0.572 - 637.9 1 2 0 0.0051 13 0 0 0 4.08E+06 8.40E+06 - - - 5.5207 0.9999 221125_WJC_METTL3_EV_vs_WT_F03.24677.24677.2 9.41E-05 22-Nov R.EGDVLTLLESER[166.11].E sp|P62857|RS28_HUMAN 1 1369.6964 0.96 39035 24677 2 1369.697283 685.8555 40S ribosomal protein S28 OS=Homo sapiens OX=9606 GN=RPS28 PE=1 SV=1 4 3798.3 - 1.35E+06 - - - 0.6118 - 2.456 0.507 - 497.1 1 2 0 0.0008 12 0 0 0 8.31E+06 8.70E+06 - - - 5.1496 1 221125_WJC_METTL3_EV_vs_WT_F03.24679.24679.3 5.75E-17 34/112 K.SPLPTPGAPVPVPAATGPYYSPYALYGQR.L sp|Q96F45|ZN503_HUMAN 1 2986.5229 2.4 39037 24679 3 2986.526651 996.5149 Zinc finger protein 503 OS=Homo sapiens OX=9606 GN=ZNF503 PE=1 SV=1 8.15 3798.5 - 1.22E+06 - - - 1.2576 - 5.519 0.765 - 1000.2 1 2 0 0.0038 29 0 0 0 8.98E+07 3.74E+07 - - - 10.9979 1 221125_WJC_METTL3_EV_vs_WT_F03.24681.24681.3 1.26E-12 18/92 K.C[160.03]EEGEDEEEAMVVAVIPRPEPMLR.V sp|Q9BUA3|SPNDC_HUMAN 1 2784.2769 4.87 39039 24681 3 2784.278868 929.0996 Spindlin interactor and repressor of chromatin-binding protein OS=Homo sapiens OX=9606 GN=SPINDOC PE=1 SV=3 3.99 3798.7 - 812786 - - - 0.7241 - 3.558 0.724 - 327.5 1 2 0 0.002 24 0 0 0 8.46E+06 1.74E+06 - - - 9.5592 1 221125_WJC_METTL3_EV_vs_WT_F03.24682.24682.3 5.59E-06 13/44 R.LFPPQWIC[160.03]C[160.03]DIR[166.11].Y sp|Q86U44|MTA70_HUMAN 1 1613.7722 -1 39040 24682 3 1613.770761 538.9313 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 5.82 3798.8 - 753442 - - - -0.8979 - 2.146 0.536 - 222 1 2 0 -0.0014 12 0 0 0 0.00E+00 0.00E+00 - - - 6.6321 0.9992 221125_WJC_METTL3_EV_vs_WT_F03.24684.24684.3 0.00896 Nov-40 R.LLASTLVHSVK.K "sp|Q9NYF8|BCLF1_HUMAN,tr|E9PKI6|E9PKI6_HUMAN,tr|A0A1W2PQ43|A0A1W2PQ43_HUMAN,tr|E9PK91|E9PK91_HUMAN,tr|E9PJA7|E9PJA7_HUMAN,tr|E9PK09|E9PK09_HUMAN,tr|E9PQN2|E9PQN2_HUMAN" 7 1166.7023 2.2 39042 24684 3 1166.702102 389.908 Bcl-2-associated transcription factor 1 OS=Homo sapiens OX=9606 GN=BCLAF1 PE=1 SV=2 8.76 3799 - 557537 - - - -0.1774 - 2.075 0.253 - 97.6 1 2 0 -0.0002 11 0 0 0 2.14E+07 9.69E+06 - - - 3.4343 0.9977 221125_WJC_METTL3_EV_vs_WT_F03.24685.24685.3 0.208 Nov-64 R.DYGVQLVEEGADTFTAK.V "sp|Q9P015|RM15_HUMAN,tr|E5RHF4|E5RHF4_HUMAN,tr|E5RIZ4|E5RIZ4_HUMAN" 3 1841.8683 0.04 39043 24685 3 1841.870485 614.9634 "39S ribosomal protein L15, mitochondrial OS=Homo sapiens OX=9606 GN=MRPL15 PE=1 SV=1" 3.92 3799.1 - 449018 - - - 1.1733 - 1.858 0.247 - 124.8 1 2 0 0.0022 17 0 0 0 2.34E+06 5.94E+07 - - - 2.8583 0.9999 221125_WJC_METTL3_EV_vs_WT_F03.24688.24688.3 0.0122 13/40 R.LLASTLVHSVK[136.11].K "sp|Q9NYF8|BCLF1_HUMAN,tr|E9PKI6|E9PKI6_HUMAN,tr|A0A1W2PQ43|A0A1W2PQ43_HUMAN,tr|E9PK91|E9PK91_HUMAN,tr|E9PJA7|E9PJA7_HUMAN,tr|E9PK09|E9PK09_HUMAN,tr|E9PQN2|E9PQN2_HUMAN" 7 1174.7165 2.2 39046 24688 3 1174.714436 392.5794 Bcl-2-associated transcription factor 1 OS=Homo sapiens OX=9606 GN=BCLAF1 PE=1 SV=2 8.76 3799.5 - 321388 - - - -1.7647 - 2.636 0.402 - 165.5 1 2 0 -0.0021 11 0 0 0 1.89E+07 8.58E+06 - - - 5.7748 1 221125_WJC_METTL3_EV_vs_WT_F03.24694.24694.3 6.22E-12 15/56 R.HFYWYLTNEGIQYLR.D "sp|P46783|RS10_HUMAN,tr|A0A2R8Y6L3|A0A2R8Y6L3_HUMAN,tr|F6U211|F6U211_HUMAN,tr|A0A1W2PQS6|A0A1W2PQS6_HUMAN,tr|A0A2R8YFH6|A0A2R8YFH6_HUMAN,tr|A0A2R8Y7H1|A0A2R8Y7H1_HUMAN,tr|S4R435|S4R435_HUMAN" 7 2001.9737 1.05 39050 24694 3 2001.975047 668.3319 40S ribosomal protein S10 OS=Homo sapiens OX=9606 GN=RPS10 PE=1 SV=1 6.75 3800.2 - 5.75E+06 - - - 0.6564 - 3.214 0.681 - 428.6 1 2 0 0.0013 15 0 0 0 1.35E+08 1.28E+08 - - - 9.1786 1 221125_WJC_METTL3_EV_vs_WT_F03.24698.24698.3 1.24E-08 19/76 K.EVFGSSLPSNWQDISLEDSR.L sp|Q8N5N7|RM50_HUMAN 1 2265.055 1.48 39054 24698 3 2265.052582 756.0256 "39S ribosomal protein L50, mitochondrial OS=Homo sapiens OX=9606 GN=MRPL50 PE=1 SV=2" 3.92 3800.5 - 1.67E+06 - - - -1.0481 - 3.313 0.604 - 359.5 1 2 0 -0.0024 20 0 0 0 1.27E+07 8.60E+06 - - - 8.1794 0.9993 221125_WJC_METTL3_EV_vs_WT_F03.24699.24699.2 0.056 20-Sep R.LLASTLVHSVK.K "sp|Q9NYF8|BCLF1_HUMAN,tr|E9PKI6|E9PKI6_HUMAN,tr|A0A1W2PQ43|A0A1W2PQ43_HUMAN,tr|E9PK91|E9PK91_HUMAN,tr|E9PJA7|E9PJA7_HUMAN,tr|E9PK09|E9PK09_HUMAN,tr|E9PQN2|E9PQN2_HUMAN" 7 1166.7023 2.3 39055 24699 2 1166.702628 584.3584 Bcl-2-associated transcription factor 1 OS=Homo sapiens OX=9606 GN=BCLAF1 PE=1 SV=2 8.76 3800.6 - 1.55E+06 - - - 0.2734 - 2.004 0.241 - 160.9 1 2 0 0.0003 11 0 0 0 4.54E+06 1.98E+06 - - - 2.7015 0.9994 221125_WJC_METTL3_EV_vs_WT_F03.24702.24702.3 0.000593 Nov-56 R.DYKVDQEIINIMQDR.L "sp|O96000|NDUBA_HUMAN,tr|H3BV16|H3BV16_HUMAN" 2 1878.9146 1.57 39058 24702 3 1878.915779 627.3121 NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 10 OS=Homo sapiens OX=9606 GN=NDUFB10 PE=1 SV=3 4.23 3801 - 717872 - - - 0.6472 - 2.02 0.415 - 179.6 1 2 1 0.0012 15 0 0 0 4.68E+06 2.98E+06 - - - 5.0011 0.7876 221125_WJC_METTL3_EV_vs_WT_F03.24704.24704.2 0.263 16-Apr L.ASTLVHSVK.K "sp|Q9NYF8|BCLF1_HUMAN,tr|E9PKI6|E9PKI6_HUMAN,tr|A0A1W2PQ43|A0A1W2PQ43_HUMAN,tr|E9PK91|E9PK91_HUMAN,tr|E9PJA7|E9PJA7_HUMAN,tr|E9PK09|E9PK09_HUMAN,tr|E9PQN2|E9PQN2_HUMAN" 7 940.5342 -1 39060 24704 2 940.533931 471.2744 Bcl-2-associated transcription factor 1 OS=Homo sapiens OX=9606 GN=BCLAF1 PE=1 SV=2 8.8 3801.3 - 458415 - - - -0.2658 - 1.29 0.253 - 29.1 11 1 0 -0.0002 9 0 0 0 0.00E+00 0.00E+00 - - - 1.1811 0.9999 221125_WJC_METTL3_EV_vs_WT_F03.24707.24707.3 0.000281 Dec-84 K.ASIPATSAVQNVLINPSLIGSK.N sp|Q16594|TAF9_HUMAN 1 2179.2212 2.56 39063 24707 3 2179.224875 727.4144 Transcription initiation factor TFIID subunit 9 OS=Homo sapiens OX=9606 GN=TAF9 PE=1 SV=1 8.8 3801.7 - 344385 - - - 1.6712 - 2.509 0.465 - 105.9 1 2 0 0.0036 22 0 0 0 8.42E+06 3.29E+06 - - - 5.9042 1 221125_WJC_METTL3_EV_vs_WT_F03.24710.24710.2 4.20E-09 13/32 K.VQAQLNTEQLLDDVVAK.R "sp|Q96QD9|UIF_HUMAN,tr|H9KVC6|H9KVC6_HUMAN" 2 1883 -1 39066 24710 2 1882.999041 942.5073 UAP56-interacting factor OS=Homo sapiens OX=9606 GN=FYTTD1 PE=1 SV=3 4.03 3802.1 - 154266 - - - -0.513 - 3.123 0.607 - 412.6 1 2 0 -0.001 17 0 0 0 0.00E+00 0.00E+00 - - - 6.3238 1 221125_WJC_METTL3_EV_vs_WT_F03.24717.24717.3 3.55E-07 17/72 R.KLELDILPLQEANAELSEK.S sp|P12270|TPR_HUMAN 1 2152.1627 -1 39071 24717 3 2152.166213 718.3948 Nucleoprotein TPR OS=Homo sapiens OX=9606 GN=TPR PE=1 SV=3 4.25 3802.9 - 477213 - - - 1.6253 - 2.971 0.597 - 354 1 2 0 0.0035 19 0 0 0 0.00E+00 0.00E+00 - - - 7.8702 1 221125_WJC_METTL3_EV_vs_WT_F03.24721.24721.2 6.45E-11 16/28 R.HFYWYLTNEGIQYLR[166.11].D "sp|P46783|RS10_HUMAN,tr|A0A2R8Y6L3|A0A2R8Y6L3_HUMAN,tr|F6U211|F6U211_HUMAN,tr|A0A1W2PQS6|A0A1W2PQS6_HUMAN,tr|A0A2R8YFH6|A0A2R8YFH6_HUMAN,tr|A0A2R8Y7H1|A0A2R8Y7H1_HUMAN,tr|S4R435|S4R435_HUMAN" 7 2011.982 1.08 39075 24721 2 2011.979325 1006.9983 40S ribosomal protein S10 OS=Homo sapiens OX=9606 GN=RPS10 PE=1 SV=1 6.75 3803.3 - 1.18E+06 - - - -1.331 - 3.203 0.688 - 736.5 1 2 0 -0.0027 15 0 0 0 1.63E+07 1.51E+07 - - - 6.9837 1 221125_WJC_METTL3_EV_vs_WT_F03.24722.24722.3 0.000258 18/76 K.ANENGLPPSSIFLSPNEAFR.S "sp|Q6W2J9|BCOR_HUMAN,tr|H7BZ37|H7BZ37_HUMAN,tr|A1A564|A1A564_HUMAN,tr|H7C2V9|H7C2V9_HUMAN,tr|H7BYY2|H7BYY2_HUMAN,tr|H7C231|H7C231_HUMAN" 6 2159.0647 3.02 39076 24722 3 2159.066312 720.6955 BCL-6 corepressor OS=Homo sapiens OX=9606 GN=BCOR PE=1 SV=1 4.53 3803.4 - 927042 - - - 0.7313 - 2.832 0.447 - 353.3 1 2 0 0.0016 20 0 0 0 1.22E+07 4.04E+06 - - - 6.0486 0.9999 221125_WJC_METTL3_EV_vs_WT_F03.24723.24723.3 3.62E-07 20/56 K.LQDREWLTELFQQSK.V "sp|P78344|IF4G2_HUMAN,tr|E9PKF8|E9PKF8_HUMAN,tr|H0Y3P2|H0Y3P2_HUMAN,tr|H0YE22|H0YE22_HUMAN,tr|D3DQV9|D3DQV9_HUMAN" 5 1919.9741 1.44 39077 24723 3 1919.974273 640.9987 Eukaryotic translation initiation factor 4 gamma 2 OS=Homo sapiens OX=9606 GN=EIF4G2 PE=1 SV=1 4.68 3803.6 - 846385 - - - 0.076 - 3.782 0.536 - 704.8 1 2 1 0.0001 15 0 0 0 7.37E+06 5.13E+06 - - - 7.9869 1 221125_WJC_METTL3_EV_vs_WT_F03.24724.24724.2 1.23E-08 15/38 K.EVFGSSLPSNWQDISLEDSR.L sp|Q8N5N7|RM50_HUMAN 1 2265.055 2.34 39078 24724 2 2265.054516 1133.5348 "39S ribosomal protein L50, mitochondrial OS=Homo sapiens OX=9606 GN=MRPL50 PE=1 SV=2" 3.92 3803.7 - 825162 - - - -0.1943 - 3.199 0.619 - 341.4 1 2 0 -0.0004 20 0 0 0 4.76E+06 2.03E+06 - - - 6.4717 1 221125_WJC_METTL3_EV_vs_WT_F03.24725.24725.2 3.95E-15 19/34 K.AQDEAFALQDVPLSSVVR.S "sp|Q9Y3B7|RM11_HUMAN,tr|H0YCD5|H0YCD5_HUMAN" 2 1943.9953 1.66 39079 24725 2 1943.99451 973.0049 "39S ribosomal protein L11, mitochondrial OS=Homo sapiens OX=9606 GN=MRPL11 PE=1 SV=1" 4.03 3803.8 - 693858 - - - -0.3837 - 3.725 0.72 - 1099.4 1 2 0 -0.0007 18 0 0 0 8.31E+06 5.01E+06 - - - 7.5918 1 221125_WJC_METTL3_EV_vs_WT_F03.24726.24726.3 5.95E-08 27/68 K.AIEPPPLDAVIEAEHTLR.E sp|Q08211|DHX9_HUMAN 1 1970.0473 0.63 39080 24726 3 1970.048323 657.6897 ATP-dependent RNA helicase A OS=Homo sapiens OX=9606 GN=DHX9 PE=1 SV=4 4.4 3804 - 588948 - - - 0.5233 - 3.75 0.601 - 960.4 1 2 0 0.001 18 0 0 0 6.65E+06 1.05E+07 - - - 8.5316 0.9981 221125_WJC_METTL3_EV_vs_WT_F03.24727.24727.3 0.113 Nov-72 R.SLASVSYAAVDFFRPSAQR.L sp|Q9BQ39|DDX50_HUMAN 1 2071.0487 0.31 39081 24727 3 2071.04855 691.3568 ATP-dependent RNA helicase DDX50 OS=Homo sapiens OX=9606 GN=DDX50 PE=1 SV=1 8.46 3804.1 - 461091 - - - -0.0671 - 1.982 0.238 - 132.2 1 2 0 -0.0001 19 0 0 0 9.61E+06 3.06E+07 - - - 2.8741 1 221125_WJC_METTL3_EV_vs_WT_F03.24728.24728.3 0.00567 Dec-40 K.VNDFLAEIFK[136.11]K[136.11].L "sp|Q14008|CKAP5_HUMAN,tr|H0YDX5|H0YDX5_HUMAN" 2 1338.7518 1.05 39082 24728 3 1338.751181 447.2579 Cytoskeleton-associated protein 5 OS=Homo sapiens OX=9606 GN=CKAP5 PE=1 SV=3 6.04 3804.2 - 460932 - - - -0.4908 - 2.196 0.468 - 242.3 1 2 0 -0.0007 11 0 0 0 4.25E+06 4.05E+06 - - - 5.9923 0.9994 221125_WJC_METTL3_EV_vs_WT_F03.24729.24729.3 5.92E-05 Dec-40 K.VNDFLAEIFKK.L "sp|Q14008|CKAP5_HUMAN,tr|H0YDX5|H0YDX5_HUMAN" 2 1322.7234 1.05 39083 24729 3 1322.718253 441.9151 Cytoskeleton-associated protein 5 OS=Homo sapiens OX=9606 GN=CKAP5 PE=1 SV=3 6.04 3804.3 - 459994 - - - -3.9199 - 2.391 0.391 - 257.2 1 2 0 -0.0052 11 0 0 0 4.25E+06 4.05E+06 - - - 5.3742 0.9998 221125_WJC_METTL3_EV_vs_WT_F03.24733.24733.2 5.06E-06 Oct-36 R.K[136.11]LELDILPLQEANAELSEK[136.11].S sp|P12270|TPR_HUMAN 1 2168.1911 -1 39087 24733 2 2168.187655 1085.1028 Nucleoprotein TPR OS=Homo sapiens OX=9606 GN=TPR PE=1 SV=3 4.25 3804.9 - 182632 - - - -1.5958 - 1.975 0.527 - 170.1 1 2 0 -0.0035 19 0 0 0 0.00E+00 0.00E+00 - - - 4.6055 0.9998 221125_WJC_METTL3_EV_vs_WT_F03.24735.24735.3 0.000875 Oct-44 R.EGFLDTLVVLHR[166.11].A "sp|P42771|CDN2A_HUMAN,sp|P42772|CDN2B_HUMAN,tr|K7ENC6|K7ENC6_HUMAN,tr|J3QRG6|J3QRG6_HUMAN,tr|K7ES20|K7ES20_HUMAN" 5 1407.775 2.5 39089 24735 3 1407.772354 470.2656 Cyclin-dependent kinase inhibitor 2A OS=Homo sapiens OX=9606 GN=CDKN2A PE=1 SV=2 5.32 3805.1 - 94411.6 - - - -1.8583 - 2.021 0.387 - 136.8 1 2 0 -0.0026 12 0 0 0 2.81E+06 1.12E+06 - - - 4.8042 1 221125_WJC_METTL3_EV_vs_WT_F03.24747.24747.2 9.60E-07 18/28 K.VSQEILELLNTTTAK.E "sp|Q86U44|MTA70_HUMAN,tr|H0YFV6|H0YFV6_HUMAN" 2 1658.9091 0.02 39097 24747 2 1659.907621 830.4618 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 4.53 3806.5 - 1.71E+06 - - - 601.9341 - 3.566 0.55 - 1450.5 1 2 0 0.9986 15 0 0 0 4.43E+08 1.82E+10 - - - 5.9157 1 221125_WJC_METTL3_EV_vs_WT_F03.24749.24749.3 3.00E-05 16/80 R.GVNWAAFHPTMPLIVSGADDR[166.11].Q "sp|P53621|COPA_HUMAN,tr|A0A3B3ISC6|A0A3B3ISC6_HUMAN,tr|A0A3B3ITV3|A0A3B3ITV3_HUMAN,tr|A0A3B3IU78|A0A3B3IU78_HUMAN,tr|A0A3B3IS84|A0A3B3IS84_HUMAN,tr|A0A3B3IU89|A0A3B3IU89_HUMAN,tr|A0A3B3ISK1|A0A3B3ISK1_HUMAN,tr|A0A3B3IT15|A0A3B3IT15_HUMAN" 8 2263.1083 0.25 39099 24749 3 2263.10983 755.3767 Coatomer subunit alpha OS=Homo sapiens OX=9606 GN=COPA PE=1 SV=2 5.21 3806.6 - 1.74E+06 - - - 0.6575 - 2.835 0.49 - 56.8 1 2 0 0.0015 21 0 0 0 5.61E+06 2.26E+07 - - - 6.5009 0.8673 221125_WJC_METTL3_EV_vs_WT_F03.24762.24762.2 0.028 14-Sep E.LLNTTTAK[136.11].E "sp|Q86U44|MTA70_HUMAN,tr|H0YFV6|H0YFV6_HUMAN" 2 868.5109 0.01 39108 24762 2 868.509084 435.2627 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 8.75 3808.1 - 648366 - - - -2.1289 - 1.609 0.248 - 190 1 1 0 -0.0018 8 0 0 0 1.06E+05 2.02E+07 - - - 2.3066 1 221125_WJC_METTL3_EV_vs_WT_F03.24767.24767.4 6.07E-08 28/132 K.VFNTTPDDLDLHVIYDVSHNIAK.V sp|Q9Y3I0|RTCB_HUMAN 1 2625.3075 1.37 39110 24767 4 2625.30171 657.3341 RNA-splicing ligase RtcB homolog OS=Homo sapiens OX=9606 GN=RTCB PE=1 SV=1 4.54 3808.8 - 1.44E+06 - - - -2.1986 - 4.238 0.565 - 436.8 1 2 0 -0.0058 23 0 0 0 9.62E+07 7.00E+07 - - - 4.61 1 221125_WJC_METTL3_EV_vs_WT_F03.24768.24768.3 1.71E-12 23/88 K.VFNTTPDDLDLHVIYDVSHNIAK.V sp|Q9Y3I0|RTCB_HUMAN 1 2625.3075 3.01 39111 24768 3 2625.300646 876.1098 RNA-splicing ligase RtcB homolog OS=Homo sapiens OX=9606 GN=RTCB PE=1 SV=1 4.54 3808.9 - 0 - - - -2.6039 - 3.673 0.606 - 529 1 2 0 -0.0068 23 0 0 0 7.17E+07 2.38E+07 - - - 8.3465 0.9999 221125_WJC_METTL3_EV_vs_WT_F03.24774.24774.4 1.03E-07 17/132 K.VFNTTPDDLDLHVIYDVSHNIAK[136.11].V sp|Q9Y3I0|RTCB_HUMAN 1 2633.3217 1.38 39115 24774 4 2633.31153 659.3377 RNA-splicing ligase RtcB homolog OS=Homo sapiens OX=9606 GN=RTCB PE=1 SV=1 4.54 3809.6 - 1.24E+06 - - - -3.8552 - 3.143 0.579 - 127.9 1 2 0 -0.0102 23 0 0 0 9.65E+07 7.00E+07 - - - 4.6338 1 221125_WJC_METTL3_EV_vs_WT_F03.24775.24775.2 4.43E-10 21/36 K.ESDLPSAILQTSGVSEFTK[136.11].K sp|Q99459|CDC5L_HUMAN 1 2016.0143 2.58 39116 24775 2 2016.005355 1009.0144 Cell division cycle 5-like protein OS=Homo sapiens OX=9606 GN=CDC5L PE=1 SV=2 4.14 3809.7 - 954358 - - - -4.4206 - 3.88 0.652 - 1578.4 1 2 0 -0.0089 19 0 0 0 5.25E+07 2.04E+07 - - - 7.1873 0.9516 221125_WJC_METTL3_EV_vs_WT_F03.24782.24782.2 0.000856 Oct-32 K.IELFGR[166.11]PHNVQPNWITL.G sp|Q86U44|MTA70_HUMAN 1 2043.0929 0.001 39120 24782 2 2043.086591 1022.5538 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 6.75 3810.5 - 2.87E+06 - - - -3.1124 - 2.027 0.474 - 158.6 1 1 0 -0.0064 17 0 0 0 0.00E+00 2.92E+07 - - - 4.2771 0.9878 221125_WJC_METTL3_EV_vs_WT_F03.24784.24784.3 0.000436 14/64 K.IELFGR[166.11]PHNVQPNWITL.G sp|Q86U44|MTA70_HUMAN 1 2043.0929 0 39121 24784 3 2043.088336 682.0383 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 6.75 3810.7 - 4.47E+06 - - - -2.2583 - 2.823 0.418 - 199.3 1 1 0 -0.0046 17 0 0 0 4.76E+05 2.38E+08 - - - 5.8208 1 221125_WJC_METTL3_EV_vs_WT_F03.24788.24788.2 2.32E-08 13/32 R.GAQVEEIWSLEPENFEK.L "sp|Q9Y5K5|UCHL5_HUMAN,tr|Q5LJA9|Q5LJA9_HUMAN,tr|Q5LJB0|Q5LJB0_HUMAN,tr|Q5LJA5|Q5LJA5_HUMAN" 4 2003.9476 2.19 39124 24788 2 2003.942896 1002.9811 Ubiquitin carboxyl-terminal hydrolase isozyme L5 OS=Homo sapiens OX=9606 GN=UCHL5 PE=1 SV=3 3.98 3811.2 - 3.04E+06 - - - -2.3658 - 2.781 0.57 - 316.8 1 2 0 -0.0047 17 0 0 0 8.41E+07 3.84E+07 - - - 5.7642 0.9957 221125_WJC_METTL3_EV_vs_WT_F03.24809.24809.2 2.54 16-Aug K.LLEVLSGER[166.11].L "sp|Q01082|SPTB2_HUMAN,sp|O43707|ACTN4_HUMAN,sp|Q08043|ACTN3_HUMAN,sp|P35609|ACTN2_HUMAN,sp|P12814|ACTN1_HUMAN,tr|A0A804HJN7|A0A804HJN7_HUMAN,tr|A0A804HK61|A0A804HK61_HUMAN,tr|G3V2E8|G3V2E8_HUMAN,tr|G3V2W4|G3V2W4_HUMAN,tr|A0A494C033|A0A494C033_HUMAN,tr|A0A804HIN7|A0A804HIN7_HUMAN,tr|G3V5M4|G3V5M4_HUMAN,tr|H9KV75|H9KV75_HUMAN,tr|A0A087WSZ2|A0A087WSZ2_HUMAN,tr|A0A804HLF4|A0A804HLF4_HUMAN,tr|A0A804HKG0|A0A804HKG0_HUMAN,tr|A0A804HIY0|A0A804HIY0_HUMAN,tr|A0A087WUZ3|A0A087WUZ3_HUMAN,tr|A0A7I2V4Y4|A0A7I2V4Y4_HUMAN,tr|A0A804HII9|A0A804HII9_HUMAN,tr|A0A804HL31|A0A804HL31_HUMAN,tr|F8W6C1|F8W6C1_HUMAN,tr|A0A494C1A0|A0A494C1A0_HUMAN,tr|A0A804HJQ9|A0A804HJQ9_HUMAN,tr|F5GXS2|F5GXS2_HUMAN,tr|A0A494C166|A0A494C166_HUMAN,tr|A0A804HI95|A0A804HI95_HUMAN,tr|A0A494C0Q3|A0A494C0Q3_HUMAN,tr|G3V2X9|G3V2X9_HUMAN,tr|A0A804HKE2|A0A804HKE2_HUMAN,tr|G3V2N5|G3V2N5_HUMAN,tr|A0A494C031|A0A494C031_HUMAN,tr|A0A804HLD0|A0A804HLD0_HUMAN,tr|H7C144|H7C144_HUMAN" 34 1024.5792 0.001 39141 24809 2 1024.578598 513.2969 "Spectrin beta chain, non-erythrocytic 1 OS=Homo sapiens OX=9606 GN=SPTBN1 PE=1 SV=2" 4.53 3813.6 - 1.42E+06 - - - -0.6168 - 1.451 0.171 - 72.7 2 2 0 -0.0006 9 0 0 0 0.00E+00 9.06E+07 - - - 1.2463 1 221125_WJC_METTL3_EV_vs_WT_F03.24810.24810.3 1.00E-10 18/52 K.SNYNFEK[136.11]PFLWLAR[166.11].K "sp|P62826|RAN_HUMAN,tr|B5MDF5|B5MDF5_HUMAN,tr|J3KQE5|J3KQE5_HUMAN,tr|B4DV51|B4DV51_HUMAN,tr|F5H018|F5H018_HUMAN" 5 1801.9271 0.82 39142 24810 3 1801.921341 601.6496 GTP-binding nuclear protein Ran OS=Homo sapiens OX=9606 GN=RAN PE=1 SV=3 8.31 3813.7 - 650788 - - - -3.1738 - 3.119 0.61 - 441.7 1 2 0 -0.0057 14 0 0 0 5.01E+07 6.09E+07 - - - 8.3623 1 221125_WJC_METTL3_EV_vs_WT_F03.24812.24812.2 5.91E-15 27/42 K.SKAEVAC[160.03]IAVYETDVFVVGTER.G "sp|P78347|GTF2I_HUMAN,sp|Q86UP8|GTD2A_HUMAN,sp|Q6EKJ0|GTD2B_HUMAN,tr|A0A494C1N8|A0A494C1N8_HUMAN,tr|A0A087WW90|A0A087WW90_HUMAN,tr|C9J6M0|C9J6M0_HUMAN,tr|A0A0D9SF80|A0A0D9SF80_HUMAN,tr|A0A494C0I1|A0A494C0I1_HUMAN,tr|A0A494C1K3|A0A494C1K3_HUMAN" 9 2442.2101 -1 39144 24812 2 2442.202698 1222.1123 General transcription factor II-I OS=Homo sapiens OX=9606 GN=GTF2I PE=1 SV=2 4.41 3814 - 0 - - - -3.0214 - 5.574 0.721 - 2191.9 1 2 1 -0.0074 22 0 0 0 0.00E+00 0.00E+00 - - - 8.588 1 221125_WJC_METTL3_EV_vs_WT_F03.24815.24815.2 6.58E-07 15/28 K.VSQEILELLNTTTAK[136.11].E "sp|Q86U44|MTA70_HUMAN,tr|H0YFV6|H0YFV6_HUMAN" 2 1666.9233 0.02 39145 24815 2 1666.918195 834.4689 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 4.53 3814.4 - 6.44E+07 - - - -3.0427 - 2.967 0.601 - 957.5 1 2 0 -0.0051 15 0 0 0 4.43E+08 1.82E+10 - - - 6.1522 0.9999 221125_WJC_METTL3_EV_vs_WT_F03.24823.24823.3 2.60E-10 21/52 K.SNYNFEKPFLWLAR.K "sp|P62826|RAN_HUMAN,tr|B5MDF5|B5MDF5_HUMAN,tr|J3KQE5|J3KQE5_HUMAN,tr|B4DV51|B4DV51_HUMAN,tr|F5H018|F5H018_HUMAN" 5 1783.9046 0.82 39151 24823 3 1783.900544 595.6421 GTP-binding nuclear protein Ran OS=Homo sapiens OX=9606 GN=RAN PE=1 SV=3 8.31 3815.3 - 2.88E+06 - - - -2.2681 - 3.31 0.421 - 558.3 1 2 0 -0.004 14 0 0 0 5.01E+07 6.10E+07 - - - 6.4135 1 221125_WJC_METTL3_EV_vs_WT_F03.24824.24824.2 3.42E-15 20/38 R.NQDLAPNSAEQASILSLVTK.L "sp|Q12905|ILF2_HUMAN,tr|B4DY09|B4DY09_HUMAN,tr|X6R6Z1|X6R6Z1_HUMAN,tr|A0A0A0MRL0|A0A0A0MRL0_HUMAN" 4 2098.0906 3.19 39152 24824 2 2098.08643 1050.0526 Interleukin enhancer-binding factor 2 OS=Homo sapiens OX=9606 GN=ILF2 PE=1 SV=2 4.37 3815.4 - 2.57E+06 - - - -1.9937 - 4.095 0.722 - 858 1 2 0 -0.0042 20 0 0 0 5.39E+07 1.69E+07 - - - 7.8384 1 221125_WJC_METTL3_EV_vs_WT_F03.24832.24832.3 1.84E-11 19/72 K.VNFPENGFLSPDK[136.11]LSLLEK[136.11].L sp|P31689|DNJA1_HUMAN 1 2162.1594 0.55 39158 24832 3 2162.147445 721.7271 DnaJ homolog subfamily A member 1 OS=Homo sapiens OX=9606 GN=DNAJA1 PE=1 SV=2 4.68 3816.4 - 4.02E+06 - - - -5.5389 - 3.722 0.637 - 326.9 1 2 1 -0.012 19 0 0 0 2.84E+07 5.17E+07 - - - 8.8675 0.9999 221125_WJC_METTL3_EV_vs_WT_F03.24834.24834.3 3.17 20/64 K.LNDLEDALQQAKEDLAR.L sp|P04264|K2C1_HUMAN 1 1940.9803 36.04 39160 24834 3 1940.9785 648.0007 "Keratin, type II cytoskeletal 1 OS=Homo sapiens OX=9606 GN=KRT1 PE=1 SV=6" 4.11 3816.6 - 6.64E+06 - - - -0.9449 - 3.925 0.486 - 669.5 1 2 1 -0.0018 17 0 0 0 9.63E+07 2.67E+06 - - - 7.4123 1 221125_WJC_METTL3_EV_vs_WT_F03.24835.24835.3 2.34E-10 19/72 K.VNFPENGFLSPDKLSLLEK.L sp|P31689|DNJA1_HUMAN 1 2146.131 0.55 39161 24835 3 2146.126978 716.3843 DnaJ homolog subfamily A member 1 OS=Homo sapiens OX=9606 GN=DNAJA1 PE=1 SV=2 4.68 3816.7 - 2.12E+06 - - - -1.8839 - 3.959 0.6 - 322.5 1 2 1 -0.004 19 0 0 0 2.84E+07 5.17E+07 - - - 8.6088 1 221125_WJC_METTL3_EV_vs_WT_F03.24837.24837.3 3.08E-09 17/60 K.C[160.03]TAPQYVDFVMSSVQK.L "sp|Q70IA6|MOB2_HUMAN,tr|A0A087WVS8|A0A087WVS8_HUMAN" 2 1858.8594 5.51 39163 24837 3 1858.858825 620.6271 MOB kinase activator 2 OS=Homo sapiens OX=9606 GN=MOB2 PE=1 SV=1 5.83 3816.9 - 1.25E+06 - - - -0.2857 - 3.117 0.611 - 393.1 1 2 0 -0.0005 16 0 0 0 2.26E+07 4.11E+06 - - - 8.269 0.9997 221125_WJC_METTL3_EV_vs_WT_F03.24839.24839.3 0.000277 15/92 K.ASGPGLNTTGVPASLPVEFTIDAK.D "sp|P21333|FLNA_HUMAN,tr|Q60FE5|Q60FE5_HUMAN" 2 2341.2165 3.35 39165 24839 3 2341.213875 781.4128 Filamin-A OS=Homo sapiens OX=9606 GN=FLNA PE=1 SV=4 4.37 3817.2 - 374308 - - - -1.1392 - 2.192 0.351 - 110.6 1 2 0 -0.0027 24 0 0 0 1.21E+07 3.62E+06 - - - 4.2754 1 221125_WJC_METTL3_EV_vs_WT_F03.24843.24843.3 1.45E-08 20/80 K.STMDNPTTTQYASLMHSFILK.A "sp|Q9NP97|DLRB1_HUMAN,tr|B1AKR6|B1AKR6_HUMAN" 2 2385.1345 1.86 39167 24843 3 2385.13337 796.0521 Dynein light chain roadblock-type 1 OS=Homo sapiens OX=9606 GN=DYNLRB1 PE=1 SV=3 6.46 3817.7 - 1.66E+06 - - - -0.4608 - 3.486 0.593 - 330.2 1 2 0 -0.0011 21 0 0 0 1.91E+07 1.02E+07 - - - 8.1449 1 221125_WJC_METTL3_EV_vs_WT_F03.24847.24847.3 2.75E-06 16/96 R.LASLFGLDQAAAGHGNEFFQYTAPK.Q sp|Q5T1M5|FKB15_HUMAN 1 2652.2973 2.12 39171 24847 3 2652.295731 885.1064 FK506-binding protein 15 OS=Homo sapiens OX=9606 GN=FKBP15 PE=1 SV=2 5.32 3818.1 - 1.14E+06 - - - -0.5735 - 3.728 0.556 - 158.6 1 2 0 -0.0015 25 0 0 0 5.88E+06 2.77E+06 - - - 7.7658 1 221125_WJC_METTL3_EV_vs_WT_F03.24848.24848.3 2.02E-10 19/100 R.NVLLDPQLVPGGGASEMAVAHALTEK[136.11].S "sp|P49368|TCPG_HUMAN,tr|B4DUR8|B4DUR8_HUMAN" 2 2624.3723 0.21 39172 24848 3 2624.365203 875.7981 T-complex protein 1 subunit gamma OS=Homo sapiens OX=9606 GN=CCT3 PE=1 SV=4 4.65 3818.3 - 1.13E+06 - - - -2.7187 - 3.835 0.599 - 254.5 1 2 0 -0.0071 26 0 0 0 4.55E+07 2.18E+08 - - - 8.3087 0.9997 221125_WJC_METTL3_EV_vs_WT_F03.24851.24851.3 0.000248 16/52 R.GDLTPLDSLIDFKR.F "sp|Q96QA5|GSDMA_HUMAN,tr|J3KRG2|J3KRG2_HUMAN" 2 1588.8461 9.94 39175 24851 3 1588.843546 530.6226 Gasdermin-A OS=Homo sapiens OX=9606 GN=GSDMA PE=1 SV=4 4.43 3818.6 - 726053 - - - -1.5905 - 2.715 0.286 - 472.6 1 2 0 -0.0025 14 0 0 0 7.26E+06 7.30E+05 - - - 4.3822 0.9999 221125_WJC_METTL3_EV_vs_WT_F03.24852.24852.3 5.36E-07 13/60 R.GVNAIVYMIDAADREK.L sp|Q9NVJ2|ARL8B_HUMAN 1 1763.8876 0.22 39176 24852 3 1763.888203 588.9698 ADP-ribosylation factor-like protein 8B OS=Homo sapiens OX=9606 GN=ARL8B PE=1 SV=1 4.56 3818.8 - 709406 - - - 0.3305 - 2.952 0.517 - 154.6 1 2 1 0.0006 16 0 0 0 4.64E+06 2.07E+07 - - - 7.0814 0.9999 221125_WJC_METTL3_EV_vs_WT_F03.24853.24853.3 3.70E-05 14/56 R.DYLHLPPEIVPATLR[166.11].R "sp|P46783|RS10_HUMAN,tr|A0A2R8Y6L3|A0A2R8Y6L3_HUMAN,tr|F6U211|F6U211_HUMAN,tr|A0A1W2PQS6|A0A1W2PQS6_HUMAN,tr|A0A2R8YFH6|A0A2R8YFH6_HUMAN,tr|A0A2R8Y7H1|A0A2R8Y7H1_HUMAN,tr|S4R435|S4R435_HUMAN" 7 1742.9595 1.16 39177 24853 3 1742.957453 581.9938 40S ribosomal protein S10 OS=Homo sapiens OX=9606 GN=RPS10 PE=1 SV=1 5.32 3818.9 - 644610 - - - -1.1607 - 2.5 0.355 - 204.4 1 2 0 -0.002 15 0 0 0 1.29E+07 1.10E+07 - - - 4.8883 1 221125_WJC_METTL3_EV_vs_WT_F03.24854.24854.3 6.57E-11 21/60 -.MR[166.11]DPVSSQYSSFLFWR[166.11].M sp|Q13015|AF1Q_HUMAN 1 2024.9682 3.55 39178 24854 3 2024.969247 675.9967 Protein AF1q OS=Homo sapiens OX=9606 GN=MLLT11 PE=1 SV=1 8.5 3819 - 603491 - - - 0.5383 - 3.846 0.595 - 859.6 1 2 1 0.0011 16 0 0 0 6.74E+07 1.90E+07 - - - 8.6297 0.9999 221125_WJC_METTL3_EV_vs_WT_F03.24855.24855.3 7.64E-05 13/56 K.LMC[160.03]PQEIVDYIADK[136.11]K[136.11].D "sp|O14561|ACPM_HUMAN,tr|H3BNK3|H3BNK3_HUMAN" 2 1837.9289 0.99 39179 24855 3 1837.924291 613.6502 "Acyl carrier protein, mitochondrial OS=Homo sapiens OX=9606 GN=NDUFAB1 PE=1 SV=3" 4.56 3819.2 - 441381 - - - -2.5039 - 2.234 0.504 - 46.8 1 2 0 -0.0046 15 0 0 0 9.27E+06 9.40E+06 - - - 6.2552 1 221125_WJC_METTL3_EV_vs_WT_F03.24859.24859.3 1.16E-14 18/76 R.NQDLAPNSAEQASILSLVTK.L "sp|Q12905|ILF2_HUMAN,tr|B4DY09|B4DY09_HUMAN,tr|X6R6Z1|X6R6Z1_HUMAN,tr|A0A0A0MRL0|A0A0A0MRL0_HUMAN" 4 2098.0906 2.37 39181 24859 3 2098.08999 700.3708 Interleukin enhancer-binding factor 2 OS=Homo sapiens OX=9606 GN=ILF2 PE=1 SV=2 4.37 3819.7 - 1.08E+07 - - - -0.2969 - 3.717 0.705 - 474.5 1 2 0 -0.0006 20 0 0 0 1.83E+08 7.75E+07 - - - 9.585 0.9999 221125_WJC_METTL3_EV_vs_WT_F03.24862.24862.3 4.24E-08 20/80 K.STMDNPTTTQYASLMHSFILK[136.11].A "sp|Q9NP97|DLRB1_HUMAN,tr|B1AKR6|B1AKR6_HUMAN" 2 2393.1487 1.88 39184 24862 3 2393.14189 798.7235 Dynein light chain roadblock-type 1 OS=Homo sapiens OX=9606 GN=DYNLRB1 PE=1 SV=3 6.46 3819.9 - 1.73E+06 - - - -2.8327 - 2.831 0.564 - 389.2 1 2 0 -0.0068 21 0 0 0 1.90E+07 1.01E+07 - - - 7.321 1 221125_WJC_METTL3_EV_vs_WT_F03.24863.24863.3 8.33E-09 17/100 R.NVLLDPQLVPGGGASEMAVAHALTEK.S "sp|P49368|TCPG_HUMAN,tr|B4DUR8|B4DUR8_HUMAN" 2 2616.3581 0.21 39185 24863 3 2616.355872 873.1267 T-complex protein 1 subunit gamma OS=Homo sapiens OX=9606 GN=CCT3 PE=1 SV=4 4.65 3820 - 1.13E+06 - - - -0.8661 - 3.351 0.622 - 191.5 1 2 0 -0.0023 26 0 0 0 4.55E+07 2.18E+08 - - - 8.2561 0.9999 221125_WJC_METTL3_EV_vs_WT_F03.24864.24864.3 1.04E-09 17/68 R.SIPVNEK[136.11]DTLTYFIYSVK[136.11].N sp|O75446|SAP30_HUMAN 1 2132.1376 0.48 39186 24864 3 2132.132075 711.7198 Histone deacetylase complex subunit SAP30 OS=Homo sapiens OX=9606 GN=SAP30 PE=1 SV=1 5.79 3820.1 - 1.10E+06 - - - -2.6021 - 3.451 0.599 - 226 1 2 1 -0.0055 18 0 0 0 7.39E+06 1.55E+07 - - - 8.3011 1 221125_WJC_METTL3_EV_vs_WT_F03.24865.24865.3 9.97E-09 14/56 R.KFDLNSPWEAFPVYR.Q sp|O75489|NDUS3_HUMAN 1 1867.9257 1.87 39187 24865 3 1867.931932 623.6492 "NADH dehydrogenase [ubiquinone] iron-sulfur protein 3, mitochondrial OS=Homo sapiens OX=9606 GN=NDUFS3 PE=1 SV=1" 6.07 3820.2 - 988227 - - - 3.3256 - 3.249 0.594 - 240 1 2 0 0.0062 15 0 0 0 2.16E+07 1.15E+07 - - - 8.2355 1 221125_WJC_METTL3_EV_vs_WT_F03.24866.24866.3 9.71E-10 16/92 K.QLIIEDPYYGNDSDFETVYQQC[160.03]VR.C sp|P24666|PPAC_HUMAN 1 2951.3284 0.49 39188 24866 3 2951.32896 984.7834 Low molecular weight phosphotyrosine protein phosphatase OS=Homo sapiens OX=9606 GN=ACP1 PE=1 SV=3 3.77 3820.4 - 764180 - - - 0.2053 - 3.548 0.691 - 184.3 1 2 0 0.0006 24 0 0 0 2.60E+06 5.34E+06 - - - 9.1851 1 221125_WJC_METTL3_EV_vs_WT_F03.24867.24867.2 4.53E-09 20/34 K.GPTEQLVSPEPEVYEILR.A "sp|O75688|PPM1B_HUMAN,tr|A0A3B3IS24|A0A3B3IS24_HUMAN,tr|C9JIR6|C9JIR6_HUMAN" 3 2055.0524 6.91 39189 24867 2 2055.04888 1028.5335 Protein phosphatase 1B OS=Homo sapiens OX=9606 GN=PPM1B PE=1 SV=1 4.09 3820.5 - 745908 - - - -1.7309 - 4.078 0.605 - 1007.6 1 2 0 -0.0036 18 0 0 0 4.93E+07 7.13E+06 - - - 6.9642 1 221125_WJC_METTL3_EV_vs_WT_F03.24869.24869.2 1.30E-08 13/28 R.AAQAPSSFQLLYDLK.L "sp|P11586|C1TC_HUMAN,tr|F5H2F4|F5H2F4_HUMAN,tr|V9GZ78|V9GZ78_HUMAN,tr|V9GYY3|V9GYY3_HUMAN,tr|A0A494C1T2|A0A494C1T2_HUMAN" 5 1650.8617 1.59 39191 24869 2 1650.859069 826.4381 "C-1-tetrahydrofolate synthase, cytoplasmic OS=Homo sapiens OX=9606 GN=MTHFD1 PE=1 SV=4" 5.88 3820.7 - 558995 - - - -1.6076 - 2.712 0.598 - 392.4 1 2 0 -0.0027 15 0 0 0 1.85E+07 1.16E+07 - - - 5.9099 1 221125_WJC_METTL3_EV_vs_WT_F03.24873.24873.3 9.60E-07 Dec-56 R.DYLHLPPEIVPATLR.R "sp|P46783|RS10_HUMAN,tr|A0A2R8Y6L3|A0A2R8Y6L3_HUMAN,tr|F6U211|F6U211_HUMAN,tr|A0A1W2PQS6|A0A1W2PQS6_HUMAN,tr|A0A2R8YFH6|A0A2R8YFH6_HUMAN,tr|A0A2R8Y7H1|A0A2R8Y7H1_HUMAN,tr|S4R435|S4R435_HUMAN" 7 1732.9512 1.16 39194 24873 3 1732.948593 578.6577 40S ribosomal protein S10 OS=Homo sapiens OX=9606 GN=RPS10 PE=1 SV=1 5.32 3821.4 - 501481 - - - -1.5078 - 2.612 0.563 - 112.1 1 2 0 -0.0026 15 0 0 0 1.29E+07 1.10E+07 - - - 7.3215 0.9931 221125_WJC_METTL3_EV_vs_WT_F03.24876.24876.2 2.99E-07 13/32 R.R[166.11]AEQDSTTVAAFASSLV.S "sp|Q86U44|MTA70_HUMAN,tr|F5H6D8|F5H6D8_HUMAN,tr|H0YFV6|H0YFV6_HUMAN,tr|B4DTN4|B4DTN4_HUMAN" 4 1761.8773 0.03 39196 24876 2 1761.87546 881.9459 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 4.37 3821.7 - 1.22E+06 - - - -1.0233 - 2.221 0.586 - 271.2 1 1 0 -0.0018 17 0 0 0 2.61E+06 1.04E+08 - - - 5.3304 0.9997 221125_WJC_METTL3_EV_vs_WT_F03.24877.24877.3 0.00018 Dec-56 K.VSQEILELLNTTTAK[136.11].E "sp|Q86U44|MTA70_HUMAN,tr|H0YFV6|H0YFV6_HUMAN" 2 1666.9233 0.01 39197 24877 3 1666.91869 556.6484 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 4.53 3821.8 - 2.24E+06 - - - -2.7458 - 2.457 0.383 - 208.8 1 2 0 -0.0046 15 0 0 0 3.47E+05 3.75E+07 - - - 5.1545 0.9997 221125_WJC_METTL3_EV_vs_WT_F03.24878.24878.3 6.61E-09 19/68 K.GPTEQLVSPEPEVYEILR[166.11].A "sp|O75688|PPM1B_HUMAN,tr|A0A3B3IS24|A0A3B3IS24_HUMAN,tr|C9JIR6|C9JIR6_HUMAN" 3 2065.0607 4.2 39198 24878 3 2065.071022 689.3608 Protein phosphatase 1B OS=Homo sapiens OX=9606 GN=PPM1B PE=1 SV=1 4.09 3821.9 - 1.50E+06 - - - 4.995 - 3.057 0.523 - 482.4 1 2 0 0.0103 18 0 0 0 1.00E+08 2.39E+07 - - - 7.1506 1 221125_WJC_METTL3_EV_vs_WT_F03.24879.24879.3 1.03E-09 18/92 K.QTQIFTTYSDNQPGVLIQVYEGER[166.11].A "sp|P0DMV8|HS71A_HUMAN,sp|P34931|HS71L_HUMAN,sp|P0DMV9|HS71B_HUMAN,tr|Q53FA3|Q53FA3_HUMAN,tr|V9GZ37|V9GZ37_HUMAN,tr|A0A0G2JIW1|A0A0G2JIW1_HUMAN" 6 2795.3642 0.14 39199 24879 3 2795.356147 932.7953 Heat shock 70 kDa protein 1A OS=Homo sapiens OX=9606 GN=HSPA1A PE=1 SV=1 4.14 3822 - 1.34E+06 - - - -2.8662 - 3.23 0.591 - 308.5 1 2 0 -0.008 24 0 0 0 1.39E+07 1.02E+08 - - - 7.8501 0.9999 221125_WJC_METTL3_EV_vs_WT_F03.24883.24883.3 0.00105 Oct-56 R.AAQAPSSFQLLYDLK.L "sp|P11586|C1TC_HUMAN,tr|F5H2F4|F5H2F4_HUMAN,tr|V9GZ78|V9GZ78_HUMAN,tr|V9GYY3|V9GYY3_HUMAN,tr|A0A494C1T2|A0A494C1T2_HUMAN" 5 1650.8617 0.99 39203 24883 3 1650.859433 551.2945 "C-1-tetrahydrofolate synthase, cytoplasmic OS=Homo sapiens OX=9606 GN=MTHFD1 PE=1 SV=4" 5.88 3822.5 - 479786 - - - -1.3872 - 2.231 0.42 - 99 1 2 0 -0.0023 15 0 0 0 3.94E+06 3.97E+06 - - - 5.3158 1 221125_WJC_METTL3_EV_vs_WT_F03.24895.24895.3 3.55E-09 16/56 K.HSQFIGYPITLFVEK[136.11].K "sp|Q58FG0|HS905_HUMAN,sp|P07900|HS90A_HUMAN,tr|G3V2J8|G3V2J8_HUMAN" 3 1785.9545 0.61 39211 24895 3 1785.953102 596.3254 Putative heat shock protein HSP 90-alpha A5 OS=Homo sapiens OX=9606 GN=HSP90AA5P PE=2 SV=1 6.75 3824 - 1.65E+06 - - - -0.7867 - 3.02 0.602 - 291.2 1 2 0 -0.0014 15 0 0 0 3.06E+07 5.01E+07 - - - 8.1353 0.9996 221125_WJC_METTL3_EV_vs_WT_F03.24896.24896.3 0.000602 16/56 K.HSQFIGYPITLFVEK.K "sp|Q58FG0|HS905_HUMAN,sp|P07900|HS90A_HUMAN,tr|G3V2J8|G3V2J8_HUMAN" 3 1777.9403 0.62 39212 24896 3 1777.936276 593.654 Putative heat shock protein HSP 90-alpha A5 OS=Homo sapiens OX=9606 GN=HSP90AA5P PE=2 SV=1 6.75 3824.1 - 1.25E+06 - - - -2.2672 - 1.904 0.391 - 250.8 1 2 0 -0.004 15 0 0 0 3.14E+07 5.05E+07 - - - 4.5785 1 221125_WJC_METTL3_EV_vs_WT_F03.24897.24897.4 9.08E-09 20/150 R.NVLLDPQLVPGGGASEMAVAHALTEK[136.11].S "sp|P49368|TCPG_HUMAN,tr|B4DUR8|B4DUR8_HUMAN" 2 2624.3723 0.19 39213 24897 4 2624.369608 657.1004 T-complex protein 1 subunit gamma OS=Homo sapiens OX=9606 GN=CCT3 PE=1 SV=4 4.65 3824.2 - 1.07E+06 - - - -1.0402 - 3.852 0.608 - 235.1 1 2 0 -0.0027 26 0 0 0 1.02E+06 5.26E+06 - - - 4.9427 1 221125_WJC_METTL3_EV_vs_WT_F03.24900.24900.3 3.83E-10 20/68 K.GPTEQLVSPEPEVYEILR.A "sp|O75688|PPM1B_HUMAN,tr|A0A3B3IS24|A0A3B3IS24_HUMAN,tr|C9JIR6|C9JIR6_HUMAN" 3 2055.0524 3.7 39214 24900 3 2055.051247 686.0248 Protein phosphatase 1B OS=Homo sapiens OX=9606 GN=PPM1B PE=1 SV=1 4.09 3824.6 - 7.82E+06 - - - -0.5791 - 3.406 0.638 - 491.7 1 2 0 -0.0012 18 0 0 0 1.01E+08 2.73E+07 - - - 8.7045 1 221125_WJC_METTL3_EV_vs_WT_F03.24901.24901.3 7.08E-05 26/88 K.KPAFNLSAFGTLSPSLGNSSILK.T sp|P49790|NU153_HUMAN 1 2348.274 1.77 39215 24901 3 2348.272459 783.7653 Nuclear pore complex protein Nup153 OS=Homo sapiens OX=9606 GN=NUP153 PE=1 SV=2 10 3824.7 - 1.13E+06 - - - -0.6549 - 4.462 0.53 - 686.7 1 2 0 -0.0015 23 0 0 0 2.35E+07 1.32E+07 - - - 7.9571 0.9996 221125_WJC_METTL3_EV_vs_WT_F03.24902.24902.2 2.09E-07 13/24 K.WNTDSVEEFLSEK[136.11].L "sp|O60613|SEP15_HUMAN,tr|A0A087X1G7|A0A087X1G7_HUMAN" 2 1590.7293 0.07 39216 24902 2 1590.724206 796.3719 Selenoprotein F OS=Homo sapiens OX=9606 GN=SELENOF PE=1 SV=4 4 3824.9 - 1.03E+06 - - - -3.2136 - 2.403 0.588 - 248.6 1 2 0 -0.0051 13 0 0 0 9.43E+05 1.41E+07 - - - 5.6325 0.9536 221125_WJC_METTL3_EV_vs_WT_F03.24903.24903.3 0.00392 Dec-64 R.R[166.11]AEQDSTTVAAFASSLV.S "sp|Q86U44|MTA70_HUMAN,tr|F5H6D8|F5H6D8_HUMAN,tr|H0YFV6|H0YFV6_HUMAN,tr|B4DTN4|B4DTN4_HUMAN" 4 1761.8773 0.02 39217 24903 3 1761.875405 588.2997 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 4.37 3825 - 770716 - - - -1.0546 - 2.082 0.315 - 147.5 1 1 0 -0.0019 17 0 0 0 3.42E+05 1.55E+07 - - - 3.904 1 221125_WJC_METTL3_EV_vs_WT_F03.24907.24907.3 9.09E-12 25/88 K.K[136.11]PAFNLSAFGTLSPSLGNSSILK[136.11].T sp|P49790|NU153_HUMAN 1 2364.3024 1.77 39219 24907 3 2364.296025 789.1081 Nuclear pore complex protein Nup153 OS=Homo sapiens OX=9606 GN=NUP153 PE=1 SV=2 10 3825.6 - 2.72E+06 - - - -2.6951 - 4.301 0.629 - 615.2 1 2 0 -0.0064 23 0 0 0 2.35E+07 1.32E+07 - - - 8.9733 0.9998 221125_WJC_METTL3_EV_vs_WT_F03.24908.24908.3 8.88E-05 18/52 K.GAVHDVKDVLDSVL.- sp|P81605|DCD_HUMAN 1 1465.7777 80.92 39220 24908 3 1465.776936 489.5998 Dermcidin OS=Homo sapiens OX=9606 GN=DCD PE=1 SV=2 4.41 3825.7 - 4.06E+06 - - - -0.4933 - 3.338 0.393 - 312.7 1 2 1 -0.0007 14 0 0 0 4.34E+07 5.36E+05 - - - 6.1247 0.9982 221125_WJC_METTL3_EV_vs_WT_F03.24909.24909.2 6.73E-06 26-Oct K.GAVHDVKDVLDSVL.- sp|P81605|DCD_HUMAN 1 1465.7777 999 39221 24909 2 1465.778364 733.8961 Dermcidin OS=Homo sapiens OX=9606 GN=DCD PE=1 SV=2 4.41 3825.7 - 1.09E+07 - - - 0.481 - 2.184 0.478 - 315.1 1 2 1 0.0007 14 0 0 0 7.92E+07 0.00E+00 - - - 4.5316 1 221125_WJC_METTL3_EV_vs_WT_F03.24911.24911.2 2.73E-14 22/46 K.QTQIFTTYSDNQPGVLIQVYEGER[166.11].A "sp|P0DMV8|HS71A_HUMAN,sp|P34931|HS71L_HUMAN,sp|P0DMV9|HS71B_HUMAN,tr|Q53FA3|Q53FA3_HUMAN,tr|V9GZ37|V9GZ37_HUMAN,tr|A0A0G2JIW1|A0A0G2JIW1_HUMAN" 6 2795.3642 0.02 39223 24911 2 2795.363078 1398.6894 Heat shock 70 kDa protein 1A OS=Homo sapiens OX=9606 GN=HSPA1A PE=1 SV=1 4.14 3825.9 - 1.46E+06 - - - -0.3867 - 4.27 0.729 - 960.1 1 2 0 -0.0011 24 0 0 0 1.72E+05 9.02E+06 - - - 7.9939 1 221125_WJC_METTL3_EV_vs_WT_F03.24915.24915.2 1.05E-08 Dec-34 K.GPTEQLVSPEPEVYEILR[166.11].A "sp|O75688|PPM1B_HUMAN,tr|A0A3B3IS24|A0A3B3IS24_HUMAN,tr|C9JIR6|C9JIR6_HUMAN" 3 2065.0607 6.91 39227 24915 2 2065.063638 1033.5376 Protein phosphatase 1B OS=Homo sapiens OX=9606 GN=PPM1B PE=1 SV=1 4.09 3826.4 - 762045 - - - 1.4193 - 2.905 0.581 - 217.4 1 2 0 0.0029 18 0 0 0 4.93E+07 7.13E+06 - - - 5.9532 1 221125_WJC_METTL3_EV_vs_WT_F03.24916.24916.3 5.05E-09 13/56 K.LMC[160.03]PQEIVDYIADKK.D "sp|O14561|ACPM_HUMAN,tr|H3BNK3|H3BNK3_HUMAN" 2 1821.9005 0.99 39228 24916 3 1821.898502 608.3074 "Acyl carrier protein, mitochondrial OS=Homo sapiens OX=9606 GN=NDUFAB1 PE=1 SV=3" 4.56 3826.6 - 689479 - - - -1.0928 - 2.635 0.47 - 212.4 1 2 0 -0.002 15 0 0 0 9.27E+06 9.40E+06 - - - 6.3077 0.9997 221125_WJC_METTL3_EV_vs_WT_F03.24917.24917.3 2.03E-05 Sep-68 K.DLLGYLNGEASTSASIDR[166.11].S "sp|Q6P1J9|CDC73_HUMAN,tr|A0A2R8Y640|A0A2R8Y640_HUMAN,tr|A0A2R8YHB3|A0A2R8YHB3_HUMAN,tr|A0A1B0GUB2|A0A1B0GUB2_HUMAN,tr|A0A3B3IRP5|A0A3B3IRP5_HUMAN" 5 1890.9199 0.98 39229 24917 3 1890.91251 631.3139 Parafibromin OS=Homo sapiens OX=9606 GN=CDC73 PE=1 SV=1 4.03 3826.7 - 461952 - - - -3.8849 - 2.364 0.472 - 74.1 1 2 0 -0.0073 18 0 0 0 4.14E+06 4.23E+06 - - - 5.9427 0.9984 221125_WJC_METTL3_EV_vs_WT_F03.24918.24918.2 0.0124 26-Dec R.ELEELKEIEADLER.Q "sp|Q8NBT2|SPC24_HUMAN,tr|K7EJH0|K7EJH0_HUMAN,tr|K7EMX1|K7EMX1_HUMAN,tr|K7EJV2|K7EJV2_HUMAN,tr|K7ESQ2|K7ESQ2_HUMAN" 5 1714.8625 0.55 39230 24918 2 1714.861753 858.4385 Kinetochore protein Spc24 OS=Homo sapiens OX=9606 GN=SPC24 PE=1 SV=2 4.06 3826.8 - 339179 - - - -0.442 - 2.556 0.438 - 485.4 1 2 1 -0.0008 14 0 0 0 2.42E+06 4.40E+06 - - - 4.6308 0.9999 221125_WJC_METTL3_EV_vs_WT_F03.24919.24919.2 2.76E-08 28-Oct K.HSQFIGYPITLFVEK.K "sp|Q58FG0|HS905_HUMAN,sp|P07900|HS90A_HUMAN,tr|G3V2J8|G3V2J8_HUMAN" 3 1777.9403 -1 39231 24919 2 1777.940828 889.9774 Putative heat shock protein HSP 90-alpha A5 OS=Homo sapiens OX=9606 GN=HSP90AA5P PE=2 SV=1 6.75 3827 - 303515 - - - 0.293 - 2.261 0.577 - 217.1 1 2 0 0.0005 15 0 0 0 0.00E+00 0.00E+00 - - - 5.3083 1 221125_WJC_METTL3_EV_vs_WT_F03.24922.24922.3 2.15E-09 24/68 R.DYFEEYGKIDTIEIITDR.Q "sp|P22626|ROA2_HUMAN,tr|A0A7I2YQN4|A0A7I2YQN4_HUMAN,tr|A0A7I2V4N0|A0A7I2V4N0_HUMAN,tr|A0A024RA28|A0A024RA28_HUMAN,tr|A0A7I2V4N1|A0A7I2V4N1_HUMAN,tr|A0A7I2V4I6|A0A7I2V4I6_HUMAN,tr|A0A087WUI2|A0A087WUI2_HUMAN,tr|A0A7I2V4S4|A0A7I2V4S4_HUMAN,tr|A0A7I2V323|A0A7I2V323_HUMAN,tr|A0A7I2V3P1|A0A7I2V3P1_HUMAN,tr|A0A7I2V3P7|A0A7I2V3P7_HUMAN" 11 2219.0634 1.82 39232 24922 3 2219.06826 740.6951 Heterogeneous nuclear ribonucleoproteins A2\B1 OS=Homo sapiens OX=9606 GN=HNRNPA2B1 PE=1 SV=2 4.02 3827.4 - 6.89E+06 - - - 2.1924 - 4.026 0.685 - 706.7 1 2 1 0.0049 18 0 0 0 5.75E+07 3.15E+07 - - - 9.6439 1 221125_WJC_METTL3_EV_vs_WT_F03.24923.24923.2 6.69E-08 14/26 K.LVINGNPITIFQER.D sp|P04406|G3P_HUMAN 1 1612.8937 1.18 39233 24923 2 1612.893943 807.4541 Glyceraldehyde-3-phosphate dehydrogenase OS=Homo sapiens OX=9606 GN=GAPDH PE=1 SV=3 6 3827.4 - 2.74E+06 - - - 0.1562 - 2.543 0.606 - 577.4 1 2 0 0.0003 14 0 0 0 3.48E+07 2.95E+07 - - - 5.859 0.9999 221125_WJC_METTL3_EV_vs_WT_F03.24924.24924.3 1.34E-08 14/64 K.SELKDFFQSYGNVVELR.L "sp|Q13283|G3BP1_HUMAN,tr|A0A7I2V5M7|A0A7I2V5M7_HUMAN,tr|A0A7I2YQN9|A0A7I2YQN9_HUMAN,tr|A0A7I2YQH0|A0A7I2YQH0_HUMAN" 4 2030.0109 0.83 39234 24924 3 2030.013749 677.6776 Ras GTPase-activating protein-binding protein 1 OS=Homo sapiens OX=9606 GN=G3BP1 PE=1 SV=1 4.68 3827.5 - 2.74E+06 - - - 1.4005 - 2.726 0.603 - 283 1 2 1 0.0028 17 0 0 0 1.53E+07 1.84E+07 - - - 7.7955 0.9999 221125_WJC_METTL3_EV_vs_WT_F03.24925.24925.3 8.93E-09 18/72 K.VR[166.11]TDITYPAGFMDVISIDK[136.11].T sp|P62701|RS4X_HUMAN 1 2158.1099 1.04 39235 24925 3 2158.113052 720.3772 "40S ribosomal protein S4, X isoform OS=Homo sapiens OX=9606 GN=RPS4X PE=1 SV=2" 4.43 3827.6 - 1.76E+06 - - - 1.455 - 3.455 0.561 - 405.9 1 2 1 0.0031 19 0 0 0 1.87E+07 1.79E+07 - - - 7.8397 1 221125_WJC_METTL3_EV_vs_WT_F03.24926.24926.3 1.93E-11 18/92 K.QTQIFTTYSDNQPGVLIQVYEGER.A "sp|P0DMV8|HS71A_HUMAN,sp|P34931|HS71L_HUMAN,sp|P0DMV9|HS71B_HUMAN,tr|Q53FA3|Q53FA3_HUMAN,tr|V9GZ37|V9GZ37_HUMAN,tr|A0A0G2JIW1|A0A0G2JIW1_HUMAN" 6 2785.3559 0.14 39236 24926 3 2785.359141 929.4592 Heat shock 70 kDa protein 1A OS=Homo sapiens OX=9606 GN=HSPA1A PE=1 SV=1 4.14 3827.7 - 1.30E+06 - - - 1.1675 - 3.235 0.661 - 298.9 1 2 0 0.0033 24 0 0 0 1.42E+07 1.02E+08 - - - 8.6354 0.9998 221125_WJC_METTL3_EV_vs_WT_F03.24928.24928.3 6.54E-07 17/52 R.ELEELKEIEADLER.Q "sp|Q8NBT2|SPC24_HUMAN,tr|K7EJH0|K7EJH0_HUMAN,tr|K7EMX1|K7EMX1_HUMAN,tr|K7EJV2|K7EJV2_HUMAN,tr|K7ESQ2|K7ESQ2_HUMAN" 5 1714.8625 2.37 39238 24928 3 1714.863214 572.6281 Kinetochore protein Spc24 OS=Homo sapiens OX=9606 GN=SPC24 PE=1 SV=2 4.06 3828 - 1.06E+06 - - - 0.4099 - 2.81 0.432 - 524.9 1 2 1 0.0007 14 0 0 0 1.10E+07 4.64E+06 - - - 6.1019 0.995 221125_WJC_METTL3_EV_vs_WT_F03.24930.24930.3 0.00112 Dec-60 K.VSQEILELLNTTTAK[136.11]E.Q "sp|Q86U44|MTA70_HUMAN,tr|H0YFV6|H0YFV6_HUMAN" 2 1795.9659 6.65 39240 24930 3 1795.96504 599.6626 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 4.52 3828.2 - 644596 - - - -0.4566 - 2.716 0.435 - 200.6 1 1 0 -0.0008 16 0 0 0 2.40E+07 3.61E+06 - - - 5.9533 0.9999 221125_WJC_METTL3_EV_vs_WT_F03.24939.24939.3 1.19E-05 16/64 K.SELK[136.11]DFFQSYGNVVELR[166.11].L "sp|Q13283|G3BP1_HUMAN,tr|A0A7I2V5M7|A0A7I2V5M7_HUMAN,tr|A0A7I2YQN9|A0A7I2YQN9_HUMAN,tr|A0A7I2YQH0|A0A7I2YQH0_HUMAN" 4 2048.0334 0.83 39247 24939 3 2048.035124 683.6851 Ras GTPase-activating protein-binding protein 1 OS=Homo sapiens OX=9606 GN=G3BP1 PE=1 SV=1 4.68 3829.3 - 1.44E+06 - - - 0.8535 - 2.938 0.556 - 383.2 1 2 1 0.0017 17 0 0 0 1.53E+07 1.84E+07 - - - 7.461 0.9999 221125_WJC_METTL3_EV_vs_WT_F03.24940.24940.3 1.14E-05 18/68 K.EK[136.11]VGEVTYVELLMDAEGK[136.11].S "sp|P52272|HNRPM_HUMAN,tr|M0R019|M0R019_HUMAN,tr|M0R0N3|M0R0N3_HUMAN,tr|A0A087X0X3|A0A087X0X3_HUMAN,tr|M0R2T0|M0R2T0_HUMAN" 5 2025.0311 1.79 39248 24940 3 2025.034867 676.0176 Heterogeneous nuclear ribonucleoprotein M OS=Homo sapiens OX=9606 GN=HNRNPM PE=1 SV=3 4.25 3829.3 - 1.78E+06 - - - 1.8558 - 3.321 0.562 - 442.6 1 2 1 0.0038 18 0 0 0 4.84E+07 2.70E+07 - - - 7.7935 1 221125_WJC_METTL3_EV_vs_WT_F03.24941.24941.2 2.57E-08 16/26 K.LVINGNPITIFQER[166.11].D sp|P04406|G3P_HUMAN 1 1622.902 1.18 39249 24941 2 1622.902095 812.4583 Glyceraldehyde-3-phosphate dehydrogenase OS=Homo sapiens OX=9606 GN=GAPDH PE=1 SV=3 6 3829.4 - 1.50E+06 - - - 0.0826 - 3.154 0.609 - 751.5 1 2 0 0.0001 14 0 0 0 3.48E+07 2.95E+07 - - - 6.4216 1 221125_WJC_METTL3_EV_vs_WT_F03.24943.24943.3 2.84E-06 17/100 K.GAMVASFSPAAGQLATPESFIEPPSK.T sp|Q9NPI6|DCP1A_HUMAN 1 2589.2785 7.13 39251 24943 3 2589.281764 864.1001 mRNA-decapping enzyme 1A OS=Homo sapiens OX=9606 GN=DCP1A PE=1 SV=3 4.53 3829.7 - 802843 - - - 1.2644 - 2.985 0.524 - 139.3 1 2 0 0.0033 26 0 0 0 1.14E+07 1.60E+06 - - - 6.8972 1 221125_WJC_METTL3_EV_vs_WT_F03.24945.24945.3 2.00E-08 19/84 K.LAQTAVTNNTAAATVLNQVLSK.V sp|Q5T481|RBM20_HUMAN 1 2227.2172 1.69 39253 24945 3 2227.221386 743.413 RNA-binding protein 20 OS=Homo sapiens OX=9606 GN=RBM20 PE=1 SV=3 8.75 3829.9 - 626361 - - - 1.8745 - 4.349 0.592 - 458.5 1 2 0 0.0042 22 0 0 0 8.44E+06 5.00E+06 - - - 8.6241 0.9898 221125_WJC_METTL3_EV_vs_WT_F03.24947.24947.3 1.08E-06 18/112 R.VVYGGGAAEISC[160.03]ALAVSQEADKC[160.03]PTLEQY.A "sp|P48643|TCPE_HUMAN,tr|E9PCA1|E9PCA1_HUMAN,tr|B7ZAR1|B7ZAR1_HUMAN,tr|E7ENZ3|E7ENZ3_HUMAN" 4 3085.4373 4.82 39255 24947 3 3085.440421 1029.4864 T-complex protein 1 subunit epsilon OS=Homo sapiens OX=9606 GN=CCT5 PE=1 SV=1 4 3830.2 - 526855 - - - 1.0268 - 3.41 0.518 - 180.2 1 1 1 0.0032 29 0 0 0 1.98E+07 4.11E+06 - - - 7.1365 0.9995 221125_WJC_METTL3_EV_vs_WT_F03.24950.24950.2 7.06E-05 20-Sep R.NPEAALSPTFR[166.11].S "sp|Q86U44|MTA70_HUMAN,tr|B4E349|B4E349_HUMAN,tr|F5H6D8|F5H6D8_HUMAN,tr|B4DTN4|B4DTN4_HUMAN" 4 1211.6174 0.02 39258 24950 2 1211.620552 606.816 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 6 3830.6 - 231247 - - - 2.5957 - 2.143 0.489 - 269.2 1 2 0 0.0031 11 0 0 0 1.59E+05 1.03E+07 - - - 4.7137 0.8313 221125_WJC_METTL3_EV_vs_WT_F03.24952.24952.2 0.000202 30-Sep K.KISSIQSIVPALEIAN.A "sp|P10809|CH60_HUMAN,tr|A0A7I2V2X6|A0A7I2V2X6_HUMAN,tr|A0A7I2YQK6|A0A7I2YQK6_HUMAN,tr|A0A7I2V599|A0A7I2V599_HUMAN,tr|A0A7I2YQ71|A0A7I2YQ71_HUMAN,tr|A0A7I2V5M1|A0A7I2V5M1_HUMAN,tr|A0A7I2V5K3|A0A7I2V5K3_HUMAN,tr|A0A7I2V369|A0A7I2V369_HUMAN" 8 1681.9614 1.63 39260 24952 2 1681.967425 841.988 "60 kDa heat shock protein, mitochondrial OS=Homo sapiens OX=9606 GN=HSPD1 PE=1 SV=2" 6 3830.8 - 158892 - - - 3.5601 - 1.71 0.364 - 143.6 1 1 0 0.006 16 0 0 0 2.88E+06 1.76E+06 - - - 3.0466 0.9999 221125_WJC_METTL3_EV_vs_WT_F03.24954.24954.3 1.45E-07 19/68 K.EKVGEVTYVELLMDAEGK.S "sp|P52272|HNRPM_HUMAN,tr|M0R019|M0R019_HUMAN,tr|M0R0N3|M0R0N3_HUMAN,tr|A0A087X0X3|A0A087X0X3_HUMAN,tr|M0R2T0|M0R2T0_HUMAN" 5 2009.0027 1.79 39261 24954 3 2009.005966 670.6748 Heterogeneous nuclear ribonucleoprotein M OS=Homo sapiens OX=9606 GN=HNRNPM PE=1 SV=3 4.25 3831.1 - 1.00E+07 - - - 1.6212 - 3.431 0.51 - 464 1 2 1 0.0033 18 0 0 0 4.84E+07 2.70E+07 - - - 7.295 0.997 221125_WJC_METTL3_EV_vs_WT_F03.24956.24956.3 2.84E-08 16/64 K.VIHDNFGIVEGLMTTVH.A "sp|P04406|G3P_HUMAN,tr|E7EUT5|E7EUT5_HUMAN" 2 1880.9455 - 39262 24956 3 1880.950025 627.9891 Glyceraldehyde-3-phosphate dehydrogenase OS=Homo sapiens OX=9606 GN=GAPDH PE=1 SV=3 5.15 3831.3 - 1.80E+06 - - - 2.4222 - 3.363 0.58 - 327.7 1 1 0 0.0046 17 0 0 0 - - - - - 8.0691 1 221125_WJC_METTL3_EV_vs_WT_F03.24958.24958.3 7.01E-11 18/72 K.STNGDTFLGGEDFDQALLR[166.11].H "sp|P38646|GRP75_HUMAN,tr|H0Y8K0|H0Y8K0_HUMAN,tr|A0A7I2V2S7|A0A7I2V2S7_HUMAN,tr|A0A7I2V2G2|A0A7I2V2G2_HUMAN,tr|A0A7I2V3F7|A0A7I2V3F7_HUMAN,tr|A0A7I2YQB2|A0A7I2YQB2_HUMAN,tr|D6RCD7|D6RCD7_HUMAN" 7 2064.9628 0.44 39264 24958 3 2064.970801 689.3282 "Stress-70 protein, mitochondrial OS=Homo sapiens OX=9606 GN=HSPA9 PE=1 SV=2" 3.84 3831.5 - 1.38E+06 - - - 3.8829 - 3.297 0.684 - 547.8 1 2 0 0.008 19 0 0 0 3.44E+07 7.89E+07 - - - 9.0947 1 221125_WJC_METTL3_EV_vs_WT_F03.24961.24961.3 1.34E-14 20/96 R.TQLWASEPGTPPLPTSLPSQNPILK.N "sp|Q9BXP5|SRRT_HUMAN,tr|H7C3A1|H7C3A1_HUMAN" 2 2671.4221 1.75 39267 24961 3 2671.43078 891.4813 Serrate RNA effector molecule homolog OS=Homo sapiens OX=9606 GN=SRRT PE=1 SV=1 5.66 3831.9 - 994651 - - - 3.2425 - 3.958 0.682 - 274.1 1 2 0 0.0087 25 0 0 0 7.49E+06 4.28E+06 - - - 9.3063 1 221125_WJC_METTL3_EV_vs_WT_F03.24963.24963.3 3.01E-07 18/96 R.TQLWASEPGTPPLPTSLPSQNPILK[136.11].N "sp|Q9BXP5|SRRT_HUMAN,tr|H7C3A1|H7C3A1_HUMAN" 2 2679.4363 1.75 39269 24963 3 2679.439728 894.1527 Serrate RNA effector molecule homolog OS=Homo sapiens OX=9606 GN=SRRT PE=1 SV=1 5.66 3832.1 - 803300 - - - 1.2727 - 3.209 0.521 - 204.1 1 2 0 0.0034 25 0 0 0 7.49E+06 4.28E+06 - - - 7.0301 0.9981 221125_WJC_METTL3_EV_vs_WT_F03.24964.24964.3 1.67E-06 18/72 K.VRTDITYPAGFMDVISIDK.T sp|P62701|RS4X_HUMAN 1 2140.0874 1.04 39270 24964 3 2140.099005 714.3698 "40S ribosomal protein S4, X isoform OS=Homo sapiens OX=9606 GN=RPS4X PE=1 SV=2" 4.43 3832.3 - 786204 - - - 5.4031 - 3.373 0.505 - 427.8 1 2 1 0.0116 19 0 0 0 1.87E+07 1.79E+07 - - - 7.154 1 221125_WJC_METTL3_EV_vs_WT_F03.24965.24965.3 3.41E-11 18/92 R.VTGQHQGYGFVEFLSEEDADYAIK[136.11].L "sp|Q15427|SF3B4_HUMAN,tr|Q5SZ64|Q5SZ64_HUMAN" 2 2710.2642 0.64 39271 24965 3 2710.272839 904.4287 Splicing factor 3B subunit 4 OS=Homo sapiens OX=9606 GN=SF3B4 PE=1 SV=1 4.17 3832.4 - 686312 - - - 3.1775 - 4.233 0.652 - 354.3 1 2 0 0.0086 24 0 0 0 2.35E+06 3.67E+06 - - - 9.1581 1 221125_WJC_METTL3_EV_vs_WT_F03.24966.24966.3 1.06E-11 20/72 K.STNGDTFLGGEDFDQALLR.H "sp|P38646|GRP75_HUMAN,tr|H0Y8K0|H0Y8K0_HUMAN,tr|A0A7I2V2S7|A0A7I2V2S7_HUMAN,tr|A0A7I2V2G2|A0A7I2V2G2_HUMAN,tr|A0A7I2V3F7|A0A7I2V3F7_HUMAN,tr|A0A7I2YQB2|A0A7I2YQB2_HUMAN,tr|D6RCD7|D6RCD7_HUMAN" 7 2054.9545 0.44 39272 24966 3 2054.960549 685.9921 "Stress-70 protein, mitochondrial OS=Homo sapiens OX=9606 GN=HSPA9 PE=1 SV=2" 3.84 3832.5 - 672886 - - - 2.9373 - 3.413 0.675 - 615.1 1 2 0 0.006 19 0 0 0 3.45E+07 7.91E+07 - - - 9.0799 1 221125_WJC_METTL3_EV_vs_WT_F03.24967.24967.3 3.78E-07 22/68 K.TLVSTVGSMVFNEGEAQR.L "sp|Q9P2E9|RRBP1_HUMAN,tr|A0A087WVV2|A0A087WVV2_HUMAN" 2 1923.936 1.41 39273 24967 3 1923.94615 642.3193 Ribosome-binding protein 1 OS=Homo sapiens OX=9606 GN=RRBP1 PE=1 SV=5 4.53 3832.6 - 580316 - - - 5.2616 - 3.364 0.654 - 458.7 1 2 0 0.0101 18 0 0 0 7.64E+06 5.43E+06 - - - 8.8495 0.9998 221125_WJC_METTL3_EV_vs_WT_F03.24968.24968.3 5.47E-09 16/80 R.AAEVWMDEYKNFYYAAVPSAR.N sp|Q10471|GALT2_HUMAN 1 2480.1471 1.26 39274 24968 3 2480.153033 827.723 Polypeptide N-acetylgalactosaminyltransferase 2 OS=Homo sapiens OX=9606 GN=GALNT2 PE=1 SV=1 4.68 3832.8 - 419921 - - - 2.3995 - 3.003 0.578 - 278.8 1 2 1 0.006 21 0 0 0 3.22E+06 2.55E+06 - - - 7.6187 1 221125_WJC_METTL3_EV_vs_WT_F03.24969.24969.3 1.11E-09 27/132 R.FGGFGGPGGVGGLGGPGGFGPGGYPGGIHEVSVN.Q sp|P35908|K22E_HUMAN 1 2970.4049 - 39275 24969 3 2970.410811 991.1422 "Keratin, type II cytoskeletal 2 epidermal OS=Homo sapiens OX=9606 GN=KRT2 PE=1 SV=2" 5.24 3832.9 - 387339 - - - 1.9883 - 4.21 0.629 - 383.7 1 1 0 0.0059 34 0 0 0 - - - - - 8.8582 0.9999 221125_WJC_METTL3_EV_vs_WT_F03.24970.24970.3 7.63E-08 10/124 R.IGPEPTTDSFIAVMHGPTEGVVPGNALVVDPR.R "sp|Q9H4M9|EHD1_HUMAN,tr|C9JC03|C9JC03_HUMAN,tr|C9JIJ3|C9JIJ3_HUMAN,tr|C9IZH1|C9IZH1_HUMAN,tr|A0A024R571|A0A024R571_HUMAN" 5 3271.6547 1.14 39276 24970 3 3271.66267 1091.5588 EH domain-containing protein 1 OS=Homo sapiens OX=9606 GN=EHD1 PE=1 SV=2 4.31 3833 - 333439 - - - 2.4318 - 2.032 0.58 - 29.1 1 2 0 0.008 32 0 0 0 2.22E+06 1.94E+06 - - - 6.6354 0.9941 221125_WJC_METTL3_EV_vs_WT_F03.24972.24972.2 6.15E-06 28-Nov R.ETDDTLVLSFVGQTR[166.11].V "sp|Q16531|DDB1_HUMAN,tr|A0A7P0TAK7|A0A7P0TAK7_HUMAN,tr|A0A7P0T870|A0A7P0T870_HUMAN,tr|A0A7P0TB30|A0A7P0TB30_HUMAN,tr|A0A7P0Z3Z5|A0A7P0Z3Z5_HUMAN,tr|F5GY55|F5GY55_HUMAN,tr|A0A7P0Z4B9|A0A7P0Z4B9_HUMAN,tr|A0A7P0T965|A0A7P0T965_HUMAN" 8 1689.8449 0.36 39278 24972 2 1689.855493 845.9297 DNA damage-binding protein 1 OS=Homo sapiens OX=9606 GN=DDB1 PE=1 SV=1 4.03 3833.3 - 284605 - - - 6.2686 - 2.216 0.509 - 321.5 1 2 0 0.0106 15 0 0 0 4.93E+05 1.36E+06 - - - 4.7534 1 221125_WJC_METTL3_EV_vs_WT_F03.24979.24979.2 1.23E-13 21/36 K.STNGDTFLGGEDFDQALLR[166.11].H "sp|P38646|GRP75_HUMAN,tr|H0Y8K0|H0Y8K0_HUMAN,tr|A0A7I2V2S7|A0A7I2V2S7_HUMAN,tr|A0A7I2V2G2|A0A7I2V2G2_HUMAN,tr|A0A7I2V3F7|A0A7I2V3F7_HUMAN,tr|A0A7I2YQB2|A0A7I2YQB2_HUMAN,tr|D6RCD7|D6RCD7_HUMAN" 7 2064.9628 0.45 39283 24979 2 2064.963571 1033.4887 "Stress-70 protein, mitochondrial OS=Homo sapiens OX=9606 GN=HSPA9 PE=1 SV=2" 3.84 3834.1 - 9.34E+06 - - - 0.3816 - 4.086 0.715 - 1053.2 1 2 0 0.0008 19 0 0 0 3.78E+07 8.37E+07 - - - 7.7823 1 221125_WJC_METTL3_EV_vs_WT_F03.24980.24980.2 1.12E-11 22/36 K.STNGDTFLGGEDFDQALLR.H "sp|P38646|GRP75_HUMAN,tr|H0Y8K0|H0Y8K0_HUMAN,tr|A0A7I2V2S7|A0A7I2V2S7_HUMAN,tr|A0A7I2V2G2|A0A7I2V2G2_HUMAN,tr|A0A7I2V3F7|A0A7I2V3F7_HUMAN,tr|A0A7I2YQB2|A0A7I2YQB2_HUMAN,tr|D6RCD7|D6RCD7_HUMAN" 7 2054.9545 0.45 39284 24980 2 2054.957075 1028.4845 "Stress-70 protein, mitochondrial OS=Homo sapiens OX=9606 GN=HSPA9 PE=1 SV=2" 3.84 3834.2 - 4.16E+06 - - - 1.2467 - 4.245 0.692 - 1131.5 1 2 0 0.0026 19 0 0 0 3.78E+07 8.37E+07 - - - 7.7057 0.9909 221125_WJC_METTL3_EV_vs_WT_F03.24981.24981.2 3.03E-06 24-Sep R.THNLEPYFESFIN.N sp|P04264|K2C1_HUMAN 1 1609.7413 - 39285 24981 2 1609.743172 805.8779 "Keratin, type II cytoskeletal 1 OS=Homo sapiens OX=9606 GN=KRT1 PE=1 SV=6" 4.5 3834.3 - 2.12E+06 - - - 1.1797 - 2.215 0.546 - 208.4 1 1 0 0.0019 13 0 0 0 - - - - - 5.1142 1 221125_WJC_METTL3_EV_vs_WT_F03.24986.24986.3 1.01E-09 20/92 K.DSGPLSDPITGKPYVPLLEAEEVR.L "sp|Q7L2E3|DHX30_HUMAN,tr|H7BXY3|H7BXY3_HUMAN" 2 2581.3275 1.67 39290 24986 3 2581.332178 861.4498 ATP-dependent RNA helicase DHX30 OS=Homo sapiens OX=9606 GN=DHX30 PE=1 SV=1 4.18 3834.9 - 856148 - - - 1.7933 - 3.691 0.628 - 293.2 1 2 0 0.0046 24 0 0 0 5.72E+06 3.42E+06 - - - 8.5734 0.9998 221125_WJC_METTL3_EV_vs_WT_F03.24988.24988.2 1.16E-10 16/28 K.DC[160.03]EVVMMIGLPGAGK[136.11].T "sp|Q00839|HNRPU_HUMAN,tr|A0A1W2PQL0|A0A1W2PQL0_HUMAN,tr|A0A1W2PPL4|A0A1W2PPL4_HUMAN,tr|A0A1W2PQ74|A0A1W2PQ74_HUMAN,tr|Q5RI18|Q5RI18_HUMAN,tr|A0A1W2PP35|A0A1W2PP35_HUMAN,tr|A0A1W2PPS1|A0A1W2PPS1_HUMAN,tr|A0A1W2PRZ7|A0A1W2PRZ7_HUMAN,tr|A0A1W2PPH7|A0A1W2PPH7_HUMAN,tr|A0A1W2PQD4|A0A1W2PQD4_HUMAN,tr|A0A1W2PP34|A0A1W2PP34_HUMAN,tr|A0A1X7SBS1|A0A1X7SBS1_HUMAN" 12 1583.7601 0.43 39292 24988 2 1583.76288 792.8873 Heterogeneous nuclear ribonucleoprotein U OS=Homo sapiens OX=9606 GN=HNRNPU PE=1 SV=6 4.37 3835.2 - 458012 - - - 1.7509 - 2.747 0.51 - 708.3 1 2 0 0.0028 15 0 0 0 1.52E+06 3.50E+06 - - - 5.2914 0.9999 221125_WJC_METTL3_EV_vs_WT_F03.24992.24992.3 8.18E-05 Nov-44 R.LFPPQWIC[160.03]C[160.03]DIR[166.11].Y sp|Q86U44|MTA70_HUMAN 1 1613.7722 0.001 39296 24992 3 1613.775149 538.9313 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 5.82 3835.7 - 304594 - - - 1.8212 - 1.999 0.499 - 141.5 1 2 0 0.0029 12 0 0 0 0.00E+00 1.35E+07 - - - 6.0225 0.9847 221125_WJC_METTL3_EV_vs_WT_F03.24995.24995.3 2.67E-05 Nov-60 Q.IQAQISALEEQLQQIR.A "sp|P13645|K1C10_HUMAN,tr|A0A1B0GVI3|A0A1B0GVI3_HUMAN" 2 1867.0163 999 39299 24995 3 1867.02139 623.3461 "Keratin, type I cytoskeletal 10 OS=Homo sapiens OX=9606 GN=KRT10 PE=1 SV=6" 4.53 3836.1 - 179916 - - - 2.7123 - 2.456 0.46 - 179.3 1 1 0 0.0051 16 0 0 0 7.50E+05 0.00E+00 - - - 5.9727 1 221125_WJC_METTL3_EV_vs_WT_F03.24999.24999.3 4.79E-08 19/76 K.AGGSASAMLQPLLDNQVGFK.N sp|P20618|PSB1_HUMAN 1 2003.0146 0.6 39302 24999 3 2003.015057 668.6788 Proteasome subunit beta type-1 OS=Homo sapiens OX=9606 GN=PSMB1 PE=1 SV=2 5.88 3836.6 - 1.26E+06 - - - 0.2227 - 3.61 0.654 - 479.4 1 2 0 0.0004 20 0 0 0 9.16E+06 1.52E+07 - - - 8.9456 1 221125_WJC_METTL3_EV_vs_WT_F03.25001.25001.3 9.10E-11 20/76 R.K[136.11]IWC[160.03]FGPDGTGPNILTDITK[136.11].G sp|P13639|EF2_HUMAN 1 2248.1533 0.64 39304 25001 3 2248.152681 750.3917 Elongation factor 2 OS=Homo sapiens OX=9606 GN=EEF2 PE=1 SV=4 5.95 3836.9 - 809630 - - - -0.2709 - 3.984 0.61 - 525.8 1 2 0 -0.0006 20 0 0 0 2.75E+06 4.34E+06 - - - 8.6942 1 221125_WJC_METTL3_EV_vs_WT_F03.25002.25002.2 1.96E-08 15/32 K.SLLDIISDPDAGTPEDK[136.11].M "sp|Q8WVM8|SCFD1_HUMAN,tr|A0A7I2V4U2|A0A7I2V4U2_HUMAN,tr|A0A7I2V4B8|A0A7I2V4B8_HUMAN,tr|H0YIZ7|H0YIZ7_HUMAN,tr|B7Z5N7|B7Z5N7_HUMAN,tr|A0A7I2V5I2|A0A7I2V5I2_HUMAN,tr|A0A7I2V590|A0A7I2V590_HUMAN,tr|G3V5E2|G3V5E2_HUMAN,tr|A0A7I2V2U5|A0A7I2V2U5_HUMAN,tr|A0A7I2V362|A0A7I2V362_HUMAN,tr|A0A7I2V448|A0A7I2V448_HUMAN,tr|A0A7I2V320|A0A7I2V320_HUMAN,tr|A0A7I2V3G4|A0A7I2V3G4_HUMAN,tr|A0A7I2V3B4|A0A7I2V3B4_HUMAN,tr|G3V2M8|G3V2M8_HUMAN,tr|A0A7I2V5H5|A0A7I2V5H5_HUMAN,tr|A0A7I2YQQ1|A0A7I2YQQ1_HUMAN" 17 1792.8822 0.92 39305 25002 2 1792.880176 897.4484 Sec1 family domain-containing protein 1 OS=Homo sapiens OX=9606 GN=SCFD1 PE=1 SV=4 3.71 3837 - 645970 - - - -1.1233 - 2.989 0.674 - 767.6 1 2 0 -0.002 17 0 0 0 3.92E+06 4.24E+06 - - - 6.7105 0.9975 221125_WJC_METTL3_EV_vs_WT_F03.25006.25006.3 0.00188 Jul-40 K.DK[136.11]QNIFEFFER[166.11].Q "sp|Q03701|CEBPZ_HUMAN,tr|C9J9W7|C9J9W7_HUMAN" 2 1489.732 0.73 39309 25006 3 1489.730351 497.5846 CCAAT\enhancer-binding protein zeta OS=Homo sapiens OX=9606 GN=CEBPZ PE=1 SV=3 4.68 3837.6 - 182806 - - - -1.1398 - 1.593 0.354 - 60.7 1 2 1 -0.0017 11 0 0 0 1.00E+06 1.38E+06 - - - 3.809 1 221125_WJC_METTL3_EV_vs_WT_F03.25012.25012.3 1.41E-11 18/76 R.NAFAC[160.03]FDEEATGTIQEDYLR.E "sp|O14950|ML12B_HUMAN,sp|P19105|ML12A_HUMAN,tr|J3QRS3|J3QRS3_HUMAN" 3 2349.0219 0.95 39314 25012 3 2349.020306 784.0146 Myosin regulatory light chain 12B OS=Homo sapiens OX=9606 GN=MYL12B PE=1 SV=2 3.83 3838.3 - 654975 - - - -0.696 - 3.188 0.695 - 435.8 1 2 0 -0.0016 20 0 0 0 1.51E+06 1.59E+06 - - - 9.1008 1 221125_WJC_METTL3_EV_vs_WT_F03.25014.25014.3 2.77E-12 14/76 R.NAFAC[160.03]FDEEATGTIQEDYLR[166.11].E "sp|O14950|ML12B_HUMAN,sp|P19105|ML12A_HUMAN,tr|J3QRS3|J3QRS3_HUMAN" 3 2359.0302 0.95 39316 25014 3 2359.033586 787.3507 Myosin regulatory light chain 12B OS=Homo sapiens OX=9606 GN=MYL12B PE=1 SV=2 3.83 3838.6 - 608122 - - - 1.4307 - 2.884 0.666 - 274.6 1 2 0 0.0034 20 0 0 0 1.51E+06 1.59E+06 - - - 8.5339 1 221125_WJC_METTL3_EV_vs_WT_F03.25017.25017.3 1.72E-13 20/132 K.LGLGIDEDEVAAEEPNAAVPDEIPPLEGDEDASR.M sp|P08238|HS90B_HUMAN 1 3531.6377 1.79 39319 25017 3 3531.64007 1178.2198 Heat shock protein HSP 90-beta OS=Homo sapiens OX=9606 GN=HSP90AB1 PE=1 SV=4 3.43 3839 - 434547 - - - 0.6816 - 3.581 0.714 - 173.5 1 2 0 0.0024 34 0 0 0 2.87E+06 1.61E+06 - - - 9.4345 1 221125_WJC_METTL3_EV_vs_WT_F03.25018.25018.2 8.17E-10 15/38 K.AGGSASAMLQPLLDNQVGFK.N sp|P20618|PSB1_HUMAN 1 2003.0146 1.16 39320 25018 2 2003.015331 1002.5146 Proteasome subunit beta type-1 OS=Homo sapiens OX=9606 GN=PSMB1 PE=1 SV=2 5.88 3839.1 - 416972 - - - 0.3595 - 3.407 0.669 - 330.1 1 2 0 0.0007 20 0 0 0 3.09E+06 2.66E+06 - - - 6.9958 1 221125_WJC_METTL3_EV_vs_WT_F03.25019.25019.2 1.76E-08 16/38 K.AGGSASAMLQPLLDNQVGFK[136.11].N sp|P20618|PSB1_HUMAN 1 2011.0288 0.9 39321 25019 2 2011.032289 1006.5217 Proteasome subunit beta type-1 OS=Homo sapiens OX=9606 GN=PSMB1 PE=1 SV=2 5.88 3839.2 - 367302 - - - 1.7295 - 2.803 0.627 - 434.4 1 2 0 0.0035 20 0 0 0 2.39E+06 2.66E+06 - - - 6.2049 1 221125_WJC_METTL3_EV_vs_WT_F03.25021.25021.3 3.40E-10 17/52 K.TYQFLQEYLDAIKK.F "sp|P48594|SPB4_HUMAN,tr|H0Y5H9|H0Y5H9_HUMAN" 2 1758.9192 0.31 39323 25021 3 1758.922851 587.3137 Serpin B4 OS=Homo sapiens OX=9606 GN=SERPINB4 PE=1 SV=2 5.73 3839.5 - 360222 - - - 2.0541 - 2.975 0.612 - 283.6 1 2 0 0.0036 14 0 0 0 1.77E+06 5.68E+06 - - - 8.2596 1 221125_WJC_METTL3_EV_vs_WT_F03.25023.25023.3 2.18E-07 15/52 R.LHFFMPGFAPLTSR[166.11].G "sp|P04350|TBB4A_HUMAN,sp|Q9BVA1|TBB2B_HUMAN,sp|A6NNZ2|TBB8B_HUMAN,sp|P07437|TBB5_HUMAN,sp|Q13885|TBB2A_HUMAN,sp|P68371|TBB4B_HUMAN,sp|Q9BUF5|TBB6_HUMAN,sp|Q3ZCM7|TBB8_HUMAN,tr|Q5ST81|Q5ST81_HUMAN,tr|Q5JP53|Q5JP53_HUMAN,tr|K7ESM5|K7ESM5_HUMAN,tr|A0A075B736|A0A075B736_HUMAN,tr|Q5SQY0|Q5SQY0_HUMAN" 13 1629.8365 0.58 39325 25023 3 1629.839566 544.2861 Tubulin beta-4A chain OS=Homo sapiens OX=9606 GN=TUBB4A PE=1 SV=2 9.76 3839.8 - 331567 - - - 1.8664 - 3.136 0.577 - 335.3 1 2 0 0.003 14 0 0 0 1.97E+06 3.38E+06 - - - 8.0096 0.9999 221125_WJC_METTL3_EV_vs_WT_F03.25024.25024.4 3.49E-09 29/126 R.TIEDAIAVLSVAEEAADR[166.11]HPER[166.11].R sp|Q96CT7|CC124_HUMAN 1 2411.2196 0.96 39326 25024 4 2411.224752 603.8122 Coiled-coil domain-containing protein 124 OS=Homo sapiens OX=9606 GN=CCDC124 PE=1 SV=1 4.35 3839.9 - 315094 - - - 2.1545 - 4.12 0.589 - 546.2 1 2 1 0.0052 22 0 0 0 1.30E+07 1.36E+07 - - - 4.8145 1 221125_WJC_METTL3_EV_vs_WT_F03.25029.25029.4 4.90E-12 30/126 R.TIEDAIAVLSVAEEAADRHPER.R sp|Q96CT7|CC124_HUMAN 1 2391.203 0.96 39330 25029 4 2391.208831 598.808 Coiled-coil domain-containing protein 124 OS=Homo sapiens OX=9606 GN=CCDC124 PE=1 SV=1 4.35 3840.6 - 1.41E+06 - - - 2.4314 - 4.327 0.644 - 583.5 1 2 1 0.0058 22 0 0 0 1.30E+07 1.36E+07 - - - 5.3091 1 221125_WJC_METTL3_EV_vs_WT_F03.25033.25033.2 1.19E-13 21/38 K.ELGGESNFGDALLDAGESMK.R "sp|Q99961|SH3G1_HUMAN,tr|M0R0I3|M0R0I3_HUMAN,tr|M0QYE0|M0QYE0_HUMAN" 3 2038.9154 1.04 39334 25033 2 2038.919337 1020.465 Endophilin-A2 OS=Homo sapiens OX=9606 GN=SH3GL1 PE=1 SV=1 3.83 3841.1 - 980202 - - - 1.955 - 3.893 0.737 - 1208.2 1 2 0 0.004 20 0 0 0 3.71E+06 3.56E+06 - - - 7.8248 0.9999 221125_WJC_METTL3_EV_vs_WT_F03.25035.25035.3 5.62E-11 18/52 K.EAFAGDDVIRDFLK.E "sp|Q5TAP6|UT14C_HUMAN,sp|Q9BVJ6|UT14A_HUMAN" 2 1594.7991 2.23 39336 25035 3 1594.801763 532.607 U3 small nucleolar RNA-associated protein 14 homolog C OS=Homo sapiens OX=9606 GN=UTP14C PE=1 SV=1 4.23 3841.3 - 903019 - - - 1.656 - 3.578 0.53 - 239.6 1 2 1 0.0026 14 0 0 0 6.42E+06 2.88E+06 - - - 7.8361 1 221125_WJC_METTL3_EV_vs_WT_F03.25036.25036.3 3.34E-08 22/76 K.NELMYQLEQDHDLQAILQER.E sp|Q08211|DHX9_HUMAN 1 2485.1907 -1 39337 25036 3 2485.196966 829.4042 ATP-dependent RNA helicase A OS=Homo sapiens OX=9606 GN=DHX9 PE=1 SV=4 4.17 3841.4 - 644568 - - - 2.506 - 4.328 0.601 - 605.9 1 2 0 0.0062 20 0 0 0 0.00E+00 0.00E+00 - - - 8.7932 1 221125_WJC_METTL3_EV_vs_WT_F03.25038.25038.3 1.07E-13 26/100 R.VYTADPYHALAPAASYGVGAVASLYR.G "sp|O43251|RFOX2_HUMAN,tr|B0QYV1|B0QYV1_HUMAN,tr|A0A0G2JRD1|A0A0G2JRD1_HUMAN,tr|A0A0G2JRA5|A0A0G2JRA5_HUMAN,tr|S4R3K7|S4R3K7_HUMAN" 5 2682.3442 1.02 39339 25038 3 2682.349877 895.122 RNA binding protein fox-1 homolog 2 OS=Homo sapiens OX=9606 GN=RBFOX2 PE=1 SV=3 6.71 3841.7 - 556923 - - - 2.1157 - 4.305 0.636 - 498.7 1 2 0 0.0057 26 0 0 0 1.23E+07 1.21E+07 - - - 8.9876 0.9998 221125_WJC_METTL3_EV_vs_WT_F03.25041.25041.2 0.000351 30-Oct R.DPYSGSTISLFQAMQK.G "sp|Q15149|PLEC_HUMAN,tr|H0YDN1|H0YDN1_HUMAN" 2 1771.8451 -1 39342 25041 2 1771.847685 886.9298 Plectin OS=Homo sapiens OX=9606 GN=PLEC PE=1 SV=3 5.83 3842.1 - 253272 - - - 1.4668 - 1.859 0.535 - 218.3 1 2 0 0.0026 16 0 0 0 0.00E+00 0.00E+00 - - - 4.5161 0.9999 221125_WJC_METTL3_EV_vs_WT_F03.25044.25044.3 7.80E-07 16/64 K.GLEHVTVDDLVAEITPK[136.11].G "sp|Q9NPA8|ENY2_HUMAN,tr|E5RHX8|E5RHX8_HUMAN" 2 1842.9818 1.64 39345 25044 3 1842.981593 615.3346 Transcription and mRNA export factor ENY2 OS=Homo sapiens OX=9606 GN=ENY2 PE=1 SV=1 4.31 3842.4 - 158517 - - - -0.1362 - 3.218 0.371 - 392.2 1 2 0 -0.0003 17 0 0 0 5.16E+07 3.15E+07 - - - 5.6289 1 221125_WJC_METTL3_EV_vs_WT_F03.25048.25048.3 1.23E-06 17/64 K.IIHDFPQFYPLGIVQHD.- "sp|P35244|RFA3_HUMAN,tr|B5MC59|B5MC59_HUMAN" 2 2038.0312 - 39348 25048 3 2038.033336 680.351 Replication protein A 14 kDa subunit OS=Homo sapiens OX=9606 GN=RPA3 PE=1 SV=1 5.22 3842.8 - 1.01E+07 - - - 1.0245 - 3.288 0.586 - 464.2 1 2 0 0.0021 17 0 0 0 - - - - - 8.0797 1 221125_WJC_METTL3_EV_vs_WT_F03.25049.25049.3 4.92E-11 17/64 K.GLEHVTVDDLVAEITPK.G "sp|Q9NPA8|ENY2_HUMAN,tr|E5RHX8|E5RHX8_HUMAN" 2 1834.9676 1.64 39349 25049 3 1834.969022 612.6632 Transcription and mRNA export factor ENY2 OS=Homo sapiens OX=9606 GN=ENY2 PE=1 SV=1 4.31 3842.9 - 5.42E+06 - - - 0.751 - 3.176 0.663 - 466 1 2 0 0.0014 17 0 0 0 5.16E+07 3.15E+07 - - - 8.8509 1 221125_WJC_METTL3_EV_vs_WT_F03.25050.25050.3 4.04E-06 15/80 R.LDLSNNDISSLPYSLGNLHLK.F sp|Q9H9A6|LRC40_HUMAN 1 2312.2012 2.19 39350 25050 3 2312.202621 771.741 Leucine-rich repeat-containing protein 40 OS=Homo sapiens OX=9606 GN=LRRC40 PE=1 SV=1 5.21 3843 - 2.68E+06 - - - 0.6033 - 2.965 0.49 - 172.8 1 2 0 0.0014 21 0 0 0 9.06E+06 4.14E+06 - - - 6.6084 1 221125_WJC_METTL3_EV_vs_WT_F03.25051.25051.3 2.25E-08 20/64 K.FSQLAEAYEVLSDEVKR.K sp|Q96EY1|DNJA3_HUMAN 1 1982.9949 0.75 39351 25051 3 1983.00023 662.0056 "DnaJ homolog subfamily A member 3, mitochondrial OS=Homo sapiens OX=9606 GN=DNAJA3 PE=1 SV=2" 4.41 3843.1 - 2.39E+06 - - - 2.6768 - 3.59 0.57 - 594 1 2 0 0.0053 17 0 0 0 5.90E+06 7.84E+06 - - - 8.1225 1 221125_WJC_METTL3_EV_vs_WT_F03.25053.25053.3 1.25E-11 22/60 R.IPDEIIDMVKEEVVAK.G "sp|Q9Y4Z0|LSM4_HUMAN,tr|U3KQK1|U3KQK1_HUMAN,tr|V9GZ56|V9GZ56_HUMAN" 3 1826.97 0.9 39353 25053 3 1826.971457 609.9973 U6 snRNA-associated Sm-like protein LSm4 OS=Homo sapiens OX=9606 GN=LSM4 PE=1 SV=1 4.18 3843.3 - 1.98E+06 - - - 0.8232 - 3.948 0.608 - 862.4 1 2 1 0.0015 16 0 0 0 2.25E+07 2.49E+07 - - - 8.8417 1 221125_WJC_METTL3_EV_vs_WT_F03.25054.25054.3 3.20E-11 24/80 R.TPSLPAVDTSYINTSLIQDYR.H "sp|O75925|PIAS1_HUMAN,tr|H3BS65|H3BS65_HUMAN" 2 2353.1802 1.79 39354 25054 3 2353.186037 785.4007 E3 SUMO-protein ligase PIAS1 OS=Homo sapiens OX=9606 GN=PIAS1 PE=1 SV=2 4.21 3843.4 - 1.96E+06 - - - 2.4992 - 3.461 0.649 - 631.3 1 2 0 0.0059 21 0 0 0 6.59E+06 3.69E+06 - - - 8.7507 0.9999 221125_WJC_METTL3_EV_vs_WT_F03.25056.25056.3 3.50E-08 13/52 K.EAFAGDDVIR[166.11]DFLK[136.11].E "sp|Q5TAP6|UT14C_HUMAN,sp|Q9BVJ6|UT14A_HUMAN" 2 1612.8216 2.23 39356 25056 3 1612.82259 538.6145 U3 small nucleolar RNA-associated protein 14 homolog C OS=Homo sapiens OX=9606 GN=UTP14C PE=1 SV=1 4.23 3843.6 - 1.52E+06 - - - 0.6188 - 2.789 0.526 - 115.1 1 2 1 0.001 14 0 0 0 6.42E+06 2.88E+06 - - - 7.1299 1 221125_WJC_METTL3_EV_vs_WT_F03.25057.25057.3 1.06E-13 20/80 R.LDLSNNDISSLPYSLGNLHLK[136.11].F sp|Q9H9A6|LRC40_HUMAN 1 2320.2154 -1 39357 25057 3 2320.218103 774.4124 Leucine-rich repeat-containing protein 40 OS=Homo sapiens OX=9606 GN=LRRC40 PE=1 SV=1 5.21 3843.8 - 1.47E+06 - - - 1.1538 - 3.691 0.642 - 434.1 1 2 0 0.0027 21 0 0 0 0.00E+00 0.00E+00 - - - 8.8278 0.9999 221125_WJC_METTL3_EV_vs_WT_F03.25058.25058.3 1.45E-05 15/60 R.SIDQFANLVLHQTVER[166.11].L sp|O15116|LSM1_HUMAN 1 1878.9827 0.94 39358 25058 3 1878.977913 627.3349 U6 snRNA-associated Sm-like protein LSm1 OS=Homo sapiens OX=9606 GN=LSM1 PE=1 SV=1 5.3 3843.8 - 1.19E+06 - - - -2.5642 - 2.852 0.461 - 181.5 1 2 0 -0.0048 16 0 0 0 5.42E+06 5.75E+06 - - - 6.3674 1 221125_WJC_METTL3_EV_vs_WT_F03.25062.25062.3 7.74E-08 18/100 R.IGWSLDSC[160.03]STQLGEEPFSYGYGGTGK.K "sp|Q9BUJ2|HNRL1_HUMAN,tr|M0QYZ0|M0QYZ0_HUMAN,tr|A0A0A0MRA5|A0A0A0MRA5_HUMAN,tr|M0R3F1|M0R3F1_HUMAN,tr|B7Z4B8|B7Z4B8_HUMAN,tr|M0QYI8|M0QYI8_HUMAN" 6 2795.2385 -1 39362 25062 3 2795.239784 932.7534 Heterogeneous nuclear ribonucleoprotein U-like protein 1 OS=Homo sapiens OX=9606 GN=HNRNPUL1 PE=1 SV=2 4.14 3844.3 - 1.07E+06 - - - 0.4679 - 2.908 0.579 - 214.2 1 2 0 0.0013 26 0 0 0 0.00E+00 0.00E+00 - - - 7.4508 0.9744 221125_WJC_METTL3_EV_vs_WT_F03.25063.25063.3 0.000631 Nov-44 K.K[136.11]VSQEILELLNT.T "sp|Q86U44|MTA70_HUMAN,tr|H0YFV6|H0YFV6_HUMAN" 2 1393.7908 0.04 39363 25063 3 1393.790366 465.6042 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 4.53 3844.4 - 1.05E+06 - - - -0.3085 - 1.931 0.36 - 172.9 1 1 0 -0.0004 12 0 0 0 2.39E+05 5.85E+06 - - - 4.3775 1 221125_WJC_METTL3_EV_vs_WT_F03.25064.25064.3 2.38E-11 21/60 R.SIDQFANLVLHQTVER.L sp|O15116|LSM1_HUMAN 1 1868.9745 0.82 39364 25064 3 1868.972541 623.9988 U6 snRNA-associated Sm-like protein LSm1 OS=Homo sapiens OX=9606 GN=LSM1 PE=1 SV=1 5.3 3844.6 - 1.00E+06 - - - -1.0273 - 4.125 0.608 - 470.4 1 2 0 -0.0019 16 0 0 0 4.44E+06 5.41E+06 - - - 8.9541 0.9999 221125_WJC_METTL3_EV_vs_WT_F03.25065.25065.3 2.39E-06 12/108 K.LVQNGTEPSSLPFLDPNAR[166.11]PLVPEVSIK[136.11].T "sp|P27708|PYR1_HUMAN,tr|F8VPD4|F8VPD4_HUMAN" 2 3034.6458 -1 39365 25065 3 3034.640141 1012.5559 CAD protein OS=Homo sapiens OX=9606 GN=CAD PE=1 SV=3 4.68 3844.7 - 750742 - - - -1.8671 - 2.289 0.502 - 96.2 1 2 0 -0.0057 28 0 0 0 0.00E+00 0.00E+00 - - - 6.0404 1 221125_WJC_METTL3_EV_vs_WT_F03.25072.25072.3 1.97E-13 22/76 K.VEEQEPELTSTPNFVVEVIK.N "sp|Q07021|C1QBP_HUMAN,tr|I3L3B0|I3L3B0_HUMAN,tr|I3L3Q7|I3L3Q7_HUMAN" 3 2286.1631 1.64 39371 25072 3 2286.167188 763.0616 "Complement component 1 Q subcomponent-binding protein, mitochondrial OS=Homo sapiens OX=9606 GN=C1QBP PE=1 SV=1" 3.98 3845.3 - 3.32E+06 - - - 1.7842 - 3.575 0.624 - 662.7 1 2 0 0.0041 20 0 0 0 3.52E+07 2.14E+07 - - - 8.5865 1 221125_WJC_METTL3_EV_vs_WT_F03.25073.25073.2 1.13E-08 19/32 Q.MIQEQISNLEAQITDVR.Q "sp|P35527|K1C9_HUMAN,tr|K7EQQ3|K7EQQ3_HUMAN" 2 1987.0044 -1 39372 25073 2 1987.001087 994.5095 "Keratin, type I cytoskeletal 9 OS=Homo sapiens OX=9606 GN=KRT9 PE=1 SV=3" 4.14 3845.5 - 2.52E+06 - - - -1.688 - 3.796 0.652 - 1064 1 1 0 -0.0034 17 0 0 0 0.00E+00 0.00E+00 - - - 7.1352 1 221125_WJC_METTL3_EV_vs_WT_F03.25075.25075.2 6.14E-12 20/38 K.VEEQEPELTSTPNFVVEVIK.N "sp|Q07021|C1QBP_HUMAN,tr|I3L3B0|I3L3B0_HUMAN,tr|I3L3Q7|I3L3Q7_HUMAN" 3 2286.1631 2.09 39374 25075 2 2286.160848 1144.0888 "Complement component 1 Q subcomponent-binding protein, mitochondrial OS=Homo sapiens OX=9606 GN=C1QBP PE=1 SV=1" 3.98 3845.7 - 1.67E+06 - - - -0.989 - 3.354 0.697 - 1007.1 1 2 0 -0.0023 20 0 0 0 1.28E+07 6.13E+06 - - - 7.1636 1 221125_WJC_METTL3_EV_vs_WT_F03.25076.25076.3 8.04E-07 19/60 K.R[166.11]QVLLSAAEAAEVILR[166.11].V sp|P78371|TCPB_HUMAN 1 1758.0267 0.66 39375 25076 3 1758.027832 587.0162 T-complex protein 1 subunit beta OS=Homo sapiens OX=9606 GN=CCT2 PE=1 SV=4 6.14 3845.8 - 1.37E+06 - - - 0.6678 - 4.081 0.535 - 844.2 1 2 0 0.0012 16 0 0 0 3.94E+06 5.93E+06 - - - 8.1129 1 221125_WJC_METTL3_EV_vs_WT_F03.25078.25078.2 1.02E-09 19/30 K.TLNDELEIIEGMKFDR.G "sp|P10809|CH60_HUMAN,tr|A0A7I2V2X6|A0A7I2V2X6_HUMAN,tr|A0A7I2V599|A0A7I2V599_HUMAN,tr|E7EXB4|E7EXB4_HUMAN,tr|A0A7I2YQ71|A0A7I2YQ71_HUMAN,tr|E7ESH4|E7ESH4_HUMAN,tr|A0A7I2V5M1|A0A7I2V5M1_HUMAN,tr|A0A7I2V5K3|A0A7I2V5K3_HUMAN,tr|A0A7I2V369|A0A7I2V369_HUMAN" 9 1921.9455 -1 39377 25078 2 1921.940002 961.98 "60 kDa heat shock protein, mitochondrial OS=Homo sapiens OX=9606 GN=HSPD1 PE=1 SV=2" 4.18 3846.1 - 1.09E+06 - - - -2.8757 - 3.913 0.549 - 1477.9 1 2 1 -0.0055 16 0 0 0 0.00E+00 0.00E+00 - - - 6.4484 1 221125_WJC_METTL3_EV_vs_WT_F03.25079.25079.2 4.36E-16 21/30 R.IPDEIIDMVKEEVVAK.G "sp|Q9Y4Z0|LSM4_HUMAN,tr|U3KQK1|U3KQK1_HUMAN,tr|V9GZ56|V9GZ56_HUMAN" 3 1826.97 -1 39378 25079 2 1826.972215 914.4923 U6 snRNA-associated Sm-like protein LSm4 OS=Homo sapiens OX=9606 GN=LSM4 PE=1 SV=1 4.18 3846.2 - 1.05E+06 - - - 1.2381 - 4.17 0.641 - 1367.5 1 2 1 0.0023 16 0 0 0 0.00E+00 0.00E+00 - - - 7.2853 1 221125_WJC_METTL3_EV_vs_WT_F03.25080.25080.2 8.30E-08 14/30 R.TMQNLEIELQSQLSMK.A sp|P02533|K1C14_HUMAN 1 1891.9383 -1 39379 25080 2 1891.926457 946.9764 "Keratin, type I cytoskeletal 14 OS=Homo sapiens OX=9606 GN=KRT14 PE=1 SV=4" 4.53 3846.4 - 964142 - - - -6.2782 - 3.152 0.617 - 762 1 2 0 -0.0119 16 0 0 0 0.00E+00 0.00E+00 - - - 6.4169 0.9999 221125_WJC_METTL3_EV_vs_WT_F03.25082.25082.3 3.43E-08 15/84 R.SVYAHFPINVVIQENGSLVEIR.N "sp|P32969|RL9_HUMAN,tr|D6RAN4|D6RAN4_HUMAN,tr|H0Y9V9|H0Y9V9_HUMAN,tr|A0A2R8Y5Y7|A0A2R8Y5Y7_HUMAN" 4 2483.3173 -1 39381 25082 3 2483.308924 828.7797 60S ribosomal protein L9 OS=Homo sapiens OX=9606 GN=RPL9 PE=1 SV=1 5.38 3846.6 - 754260 - - - -3.3564 - 3.583 0.483 - 258.1 1 2 0 -0.0083 22 0 0 0 0.00E+00 0.00E+00 - - - 6.9483 0.9999 221125_WJC_METTL3_EV_vs_WT_F03.25088.25088.3 2.02E-07 16/60 K.TLNDELEIIEGMK[136.11]FDR[166.11].G "sp|P10809|CH60_HUMAN,tr|A0A7I2V2X6|A0A7I2V2X6_HUMAN,tr|A0A7I2V599|A0A7I2V599_HUMAN,tr|E7EXB4|E7EXB4_HUMAN,tr|A0A7I2YQ71|A0A7I2YQ71_HUMAN,tr|E7ESH4|E7ESH4_HUMAN,tr|A0A7I2V5M1|A0A7I2V5M1_HUMAN,tr|A0A7I2V5K3|A0A7I2V5K3_HUMAN,tr|A0A7I2V369|A0A7I2V369_HUMAN" 9 1939.968 1.19 39386 25088 3 1939.966476 647.6633 "60 kDa heat shock protein, mitochondrial OS=Homo sapiens OX=9606 GN=HSPD1 PE=1 SV=2" 4.18 3847.4 - 481518 - - - -0.7851 - 3.042 0.469 - 217.2 1 2 1 -0.0015 16 0 0 0 3.04E+07 2.56E+07 - - - 6.623 1 221125_WJC_METTL3_EV_vs_WT_F03.25090.25090.2 4.29E-10 15/38 K.VEEQEPELTSTPNFVVEVIK[136.11].N "sp|Q07021|C1QBP_HUMAN,tr|I3L3B0|I3L3B0_HUMAN,tr|I3L3Q7|I3L3Q7_HUMAN" 3 2294.1773 2.09 39388 25090 2 2294.177609 1148.0959 "Complement component 1 Q subcomponent-binding protein, mitochondrial OS=Homo sapiens OX=9606 GN=C1QBP PE=1 SV=1" 3.98 3847.6 - 1.33E+06 - - - 0.1308 - 2.896 0.673 - 469.9 1 2 0 0.0003 20 0 0 0 1.28E+07 6.13E+06 - - - 6.6259 0.9999 221125_WJC_METTL3_EV_vs_WT_F03.25091.25091.2 5.06E-10 26-Dec K.AFYPEEISSMVLTK[136.11].M "sp|P0DMV8|HS71A_HUMAN,sp|P34931|HS71L_HUMAN,sp|P0DMV9|HS71B_HUMAN,tr|Q53FA3|Q53FA3_HUMAN,tr|A0A0G2JIW1|A0A0G2JIW1_HUMAN" 5 1621.8153 0.001 39389 25091 2 1621.814984 811.9149 Heat shock 70 kDa protein 1A OS=Homo sapiens OX=9606 GN=HSPA1A PE=1 SV=1 4.53 3847.8 - 839709 - - - -0.1924 - 2.278 0.546 - 320.2 1 2 0 -0.0003 14 0 0 0 0.00E+00 1.18E+07 - - - 5.1397 1 221125_WJC_METTL3_EV_vs_WT_F03.25095.25095.3 0.00057 21/60 K.GFDQTINLILDESHER.V "sp|O95777|LSM8_HUMAN,tr|C9JNV3|C9JNV3_HUMAN,tr|C9JIZ0|C9JIZ0_HUMAN,tr|F2Z2Y6|F2Z2Y6_HUMAN" 4 1885.917 3.17 39393 25095 3 1885.920898 629.6463 U6 snRNA-associated Sm-like protein LSm8 OS=Homo sapiens OX=9606 GN=LSM8 PE=1 SV=3 4.31 3848.3 - 510974 - - - 2.0637 - 3.404 0.523 - 489.5 1 2 0 0.0039 16 0 0 0 4.30E+07 1.36E+07 - - - 7.5129 1 221125_WJC_METTL3_EV_vs_WT_F03.25096.25096.3 4.62E-13 21/88 K.IKWGDAGAEYVVESTGVFTTMEK.A "sp|P04406|G3P_HUMAN,tr|E7EUT5|E7EUT5_HUMAN" 2 2517.2097 0.94 39394 25096 3 2517.220504 840.0772 Glyceraldehyde-3-phosphate dehydrogenase OS=Homo sapiens OX=9606 GN=GAPDH PE=1 SV=3 4.41 3848.4 - 388389 - - - 4.2754 - 3.955 0.614 - 628.2 1 2 1 0.0108 23 0 0 0 4.07E+07 4.30E+07 - - - 8.6081 0.9037 221125_WJC_METTL3_EV_vs_WT_F03.25097.25097.2 0.174 22-Sep T.DQDFYSLLGVSK.T "sp|Q8IXB1|DJC10_HUMAN,tr|A0A7P0TB22|A0A7P0TB22_HUMAN,tr|A0A7P0Z4F2|A0A7P0Z4F2_HUMAN,tr|A0A7P0Z431|A0A7P0Z431_HUMAN,tr|A0A7P0TB97|A0A7P0TB97_HUMAN,tr|A0A7P0T8Y3|A0A7P0T8Y3_HUMAN,tr|A0A7P0TAQ9|A0A7P0TAQ9_HUMAN,tr|E7EP04|E7EP04_HUMAN,tr|A0A7P0T9B7|A0A7P0T9B7_HUMAN,tr|A0A494C1G5|A0A494C1G5_HUMAN,tr|A0A7P0TB83|A0A7P0TB83_HUMAN" 11 1370.6718 -1 39395 25097 2 1370.676674 686.3432 DnaJ homolog subfamily C member 10 OS=Homo sapiens OX=9606 GN=DNAJC10 PE=1 SV=2 4.21 3848.5 - 378002 - - - 3.5581 - 2.064 0.381 - 183.8 1 1 0 0.0049 12 0 0 0 0.00E+00 0.00E+00 - - - 3.7602 1 221125_WJC_METTL3_EV_vs_WT_F03.25098.25098.3 1.35E-10 18/76 R.IVELPAPADFLSLSSETK[136.11]PK[136.11].L sp|Q6P2E9|EDC4_HUMAN 1 2157.1904 0.85 39396 25098 3 2157.191812 720.0707 Enhancer of mRNA-decapping protein 4 OS=Homo sapiens OX=9606 GN=EDC4 PE=1 SV=1 4.68 3848.7 - 376254 - - - 0.6606 - 3.283 0.597 - 359.8 1 2 0 0.0014 20 0 0 0 4.96E+06 5.83E+06 - - - 8.0795 1 221125_WJC_METTL3_EV_vs_WT_F03.25100.25100.3 1.85E-07 13/76 K.VAYTEADYYHTELWMEQALR.Q sp|P13674|P4HA1_HUMAN 1 2488.1369 3.31 39398 25100 3 2488.137498 830.3862 Prolyl 4-hydroxylase subunit alpha-1 OS=Homo sapiens OX=9606 GN=P4HA1 PE=1 SV=2 4.4 3848.9 - 298179 - - - 0.2359 - 2.896 0.571 - 177.8 1 2 0 0.0006 20 0 0 0 1.99E+06 6.01E+05 - - - 7.4856 0.9996 221125_WJC_METTL3_EV_vs_WT_F03.25101.25101.4 0.000164 10/150 R.VYTADPYHALAPAASYGVGAVASLYR.G "sp|O43251|RFOX2_HUMAN,tr|B0QYV1|B0QYV1_HUMAN,tr|A0A0G2JRD1|A0A0G2JRD1_HUMAN,tr|A0A0G2JRA5|A0A0G2JRA5_HUMAN,tr|S4R3K7|S4R3K7_HUMAN" 5 2682.3442 2.21 39399 25101 4 2682.351544 671.5933 RNA binding protein fox-1 homolog 2 OS=Homo sapiens OX=9606 GN=RBFOX2 PE=1 SV=3 6.71 3849.1 - 200180 - - - 2.7372 - 1.992 0.403 - 46.9 1 2 0 0.0073 26 0 0 0 1.85E+06 8.34E+05 - - - 2.9491 1 221125_WJC_METTL3_EV_vs_WT_F03.25105.25105.3 1.71E-08 16/60 K.GFDQTINLILDESHER[166.11].V "sp|O95777|LSM8_HUMAN,tr|C9JNV3|C9JNV3_HUMAN,tr|C9JIZ0|C9JIZ0_HUMAN,tr|F2Z2Y6|F2Z2Y6_HUMAN" 4 1895.9253 3.15 39401 25105 3 1895.926413 632.9824 U6 snRNA-associated Sm-like protein LSm8 OS=Homo sapiens OX=9606 GN=LSM8 PE=1 SV=3 4.31 3849.6 - 715230 - - - 0.5997 - 2.78 0.571 - 219.5 1 2 0 0.0011 16 0 0 0 4.30E+07 1.37E+07 - - - 7.5292 1 221125_WJC_METTL3_EV_vs_WT_F03.25106.25106.2 2.94E-08 18/32 K.GLEHVTVDDLVAEITPK.G "sp|Q9NPA8|ENY2_HUMAN,tr|E5RHX8|E5RHX8_HUMAN" 2 1834.9676 2.16 39402 25106 2 1834.969274 918.4911 Transcription and mRNA export factor ENY2 OS=Homo sapiens OX=9606 GN=ENY2 PE=1 SV=1 4.31 3849.7 - 1.26E+06 - - - 0.8883 - 2.688 0.671 - 519.3 1 2 0 0.0016 17 0 0 0 9.05E+06 4.19E+06 - - - 6.4275 0.9999 221125_WJC_METTL3_EV_vs_WT_F03.25107.25107.3 8.54E-08 24/88 K.IK[136.11]WGDAGAEYVVESTGVFTTMEK[136.11].A "sp|P04406|G3P_HUMAN,tr|E7EUT5|E7EUT5_HUMAN" 2 2533.2381 0.94 39403 25107 3 2533.24146 845.42 Glyceraldehyde-3-phosphate dehydrogenase OS=Homo sapiens OX=9606 GN=GAPDH PE=1 SV=3 4.41 3849.8 - 1.83E+06 - - - 1.3098 - 4.192 0.586 - 843.5 1 2 1 0.0033 23 0 0 0 4.07E+07 4.30E+07 - - - 8.4346 1 221125_WJC_METTL3_EV_vs_WT_F03.25111.25111.3 2.56E-08 14/76 R.IVELPAPADFLSLSSETKPK.L sp|Q6P2E9|EDC4_HUMAN 1 2141.162 1.2 39407 25111 3 2141.168067 714.7279 Enhancer of mRNA-decapping protein 4 OS=Homo sapiens OX=9606 GN=EDC4 PE=1 SV=1 4.68 3850.2 - 314513 - - - 2.8396 - 3.053 0.585 - 196.8 1 2 0 0.0061 20 0 0 0 2.31E+06 1.92E+06 - - - 7.7682 1 221125_WJC_METTL3_EV_vs_WT_F03.25112.25112.3 7.87E-08 26/60 K.RQVLLSAAEAAEVILR.V sp|P78371|TCPB_HUMAN 1 1738.0101 0.66 39408 25112 3 1738.013379 580.344 T-complex protein 1 subunit beta OS=Homo sapiens OX=9606 GN=CCT2 PE=1 SV=4 6.14 3850.4 - 288431 - - - 1.8763 - 4.671 0.596 - 1507.7 1 2 0 0.0033 16 0 0 0 4.14E+06 6.32E+06 - - - 9.1389 0.9997 221125_WJC_METTL3_EV_vs_WT_F03.25113.25113.3 1.99E-06 13/88 R.QSHTLPFPPPPALPFYPASAYPR.H "sp|Q9NZB2|F120A_HUMAN,tr|A0A0C4DG79|A0A0C4DG79_HUMAN,tr|A0A494C0Y9|A0A494C0Y9_HUMAN" 3 2550.306 0.81 39409 25113 3 2550.31795 851.1093 Constitutive coactivator of PPAR-gamma-like protein 1 OS=Homo sapiens OX=9606 GN=FAM120A PE=1 SV=2 8.6 3850.5 - 285242 - - - 4.699 - 2.912 0.547 - 101.5 1 2 0 0.012 23 0 0 0 2.82E+06 3.50E+06 - - - 7.1426 0.8891 221125_WJC_METTL3_EV_vs_WT_F03.25116.25116.2 0.0255 22-Aug K.KVSQEILELLNT.T "sp|Q86U44|MTA70_HUMAN,tr|H0YFV6|H0YFV6_HUMAN" 2 1385.7766 0.03 39412 25116 2 1385.779169 693.8956 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 4.53 3850.9 - 202409 - - - 1.8567 - 1.79 0.246 - 212.4 1 1 0 0.0026 12 0 0 0 1.65E+07 5.46E+08 - - - 2.3891 0.9878 221125_WJC_METTL3_EV_vs_WT_F03.25119.25119.2 0.0766 30-May K.R[166.11]QVLLSAAEAAEVILR[166.11].V sp|P78371|TCPB_HUMAN 1 1758.0267 -1 39415 25119 2 1758.026742 880.0206 T-complex protein 1 subunit beta OS=Homo sapiens OX=9606 GN=CCT2 PE=1 SV=4 6.14 3851.3 - 131464 - - - 0.0478 - 1.408 0.129 - 14.9 6 2 0 0.0001 16 0 0 0 0.00E+00 0.00E+00 - - - 0.4874 0.9782 221125_WJC_METTL3_EV_vs_WT_F03.25124.25124.2 0.000573 22-Dec K.K[136.11]VSQEILELLNT.T "sp|Q86U44|MTA70_HUMAN,tr|H0YFV6|H0YFV6_HUMAN" 2 1393.7908 0.03 39418 25124 2 1393.792916 697.9027 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 4.53 3852 - 4.74E+06 - - - 1.521 - 2.153 0.398 - 492.3 1 1 0 0.0021 12 0 0 0 1.65E+07 5.46E+08 - - - 3.9977 0.9999 221125_WJC_METTL3_EV_vs_WT_F03.25125.25125.3 4.38E-11 19/64 R.TPQEAITDGLEIVVSPR.S "sp|Q99496|RING2_HUMAN,tr|X6RFN3|X6RFN3_HUMAN" 2 1823.9629 1.23 39419 25125 3 1823.969363 608.9949 E3 ubiquitin-protein ligase RING2 OS=Homo sapiens OX=9606 GN=RNF2 PE=1 SV=1 4.14 3852.1 - 1.45E+06 - - - 3.5472 - 3.16 0.585 - 465.9 1 2 0 0.0065 17 0 0 0 3.50E+07 2.86E+07 - - - 7.9671 0.9989 221125_WJC_METTL3_EV_vs_WT_F03.25129.25129.3 0.0075 Sep-60 K.EVGSHFDDFVTNLIEK[136.11].S "sp|P35610|SOAT1_HUMAN,tr|B1APM4|B1APM4_HUMAN" 2 1856.9036 1.44 39423 25129 3 1856.907095 619.9751 Sterol O-acyltransferase 1 OS=Homo sapiens OX=9606 GN=SOAT1 PE=1 SV=3 4.31 3852.6 - 403166 - - - 1.8854 - 1.654 0.343 - 95.6 1 2 0 0.0035 16 0 0 0 2.84E+06 1.97E+06 - - - 3.6543 0.9892 221125_WJC_METTL3_EV_vs_WT_F03.25132.25132.2 5.27E-05 16/32 K.TVQLTSSELESTLETLK[136.11].A "sp|P42704|LPPRC_HUMAN,tr|A0A804HI14|A0A804HI14_HUMAN,tr|A0A804HL40|A0A804HL40_HUMAN,tr|A0A804HKJ0|A0A804HKJ0_HUMAN,tr|A0A804HKR3|A0A804HKR3_HUMAN,tr|A0A804HIN4|A0A804HIN4_HUMAN,tr|A0A804HLG8|A0A804HLG8_HUMAN,tr|A0A804HIV5|A0A804HIV5_HUMAN,tr|A0A804HHY9|A0A804HHY9_HUMAN,tr|A0A804HJH8|A0A804HJH8_HUMAN,tr|B8ZZ38|B8ZZ38_HUMAN,tr|A0A804HI40|A0A804HI40_HUMAN,tr|A0A804HJZ1|A0A804HJZ1_HUMAN,tr|C9JCA9|C9JCA9_HUMAN,tr|A0A804HIQ7|A0A804HIQ7_HUMAN,tr|A0A804HK30|A0A804HK30_HUMAN,tr|A0A804HKI2|A0A804HKI2_HUMAN,tr|A0A804HJI0|A0A804HJI0_HUMAN,tr|A0A804HIG4|A0A804HIG4_HUMAN,tr|A0A804HK02|A0A804HK02_HUMAN" 20 1885.9976 -1 39426 25132 2 1886.01295 944.0061 "Leucine-rich PPR motif-containing protein, mitochondrial OS=Homo sapiens OX=9606 GN=LRPPRC PE=1 SV=3" 4.25 3853 - 296439 - - - 8.1633 - 2.92 0.489 - 619.6 1 2 0 0.0154 17 0 0 0 0.00E+00 0.00E+00 - - - 5.2825 0.9999 221125_WJC_METTL3_EV_vs_WT_F03.25133.25133.4 1.26E-07 19/120 R.SLLHGDFHAFSAGPGLFSYIR.H "sp|P08195|4F2_HUMAN,tr|A0A7P0TAN7|A0A7P0TAN7_HUMAN,tr|J3KPF3|J3KPF3_HUMAN,tr|F5H056|F5H056_HUMAN,tr|F5GZI0|F5GZI0_HUMAN,tr|A0A7P0T9F7|A0A7P0T9F7_HUMAN,tr|A0A7P0TBF8|A0A7P0TBF8_HUMAN,tr|A0A7P0Z4A0|A0A7P0Z4A0_HUMAN,tr|F5GZS6|F5GZS6_HUMAN,tr|A0A7P0Z4P5|A0A7P0Z4P5_HUMAN" 10 2291.1487 0.33 39427 25133 4 2291.156352 573.7945 4F2 cell-surface antigen heavy chain OS=Homo sapiens OX=9606 GN=SLC3A2 PE=1 SV=3 6.66 3853.1 - 289287 - - - 3.3237 - 3.33 0.557 - 236 1 2 0 0.0076 21 0 0 0 9.08E+05 2.78E+06 - - - 4.4698 0.9789 221125_WJC_METTL3_EV_vs_WT_F03.25134.25134.3 0.00506 Sep-76 R.QISQEHTPVALEAYFVPLVK.R sp|P30154|2AAB_HUMAN 1 2268.2154 1.82 39428 25134 3 2268.227953 757.0791 Serine\threonine-protein phosphatase 2A 65 kDa regulatory subunit A beta isoform OS=Homo sapiens OX=9606 GN=PPP2R1B PE=1 SV=3 5.4 3853.3 - 240326 - - - 5.5255 - 1.956 0.289 - 58 1 2 0 0.0125 20 0 0 0 9.12E+05 5.00E+05 - - - 3.3862 0.9996 221125_WJC_METTL3_EV_vs_WT_F03.25135.25135.3 1.28E-05 Dec-64 R.DPPDPYVSLLLLPDKNR.G sp|Q9BSJ8|ESYT1_HUMAN 1 1951.0415 2.22 39429 25135 3 1951.046308 651.3544 Extended synaptotagmin-1 OS=Homo sapiens OX=9606 GN=ESYT1 PE=1 SV=1 4.43 3853.4 - 239872 - - - 2.4756 - 2.463 0.49 - 128.7 1 2 1 0.0048 17 0 0 0 9.99E+05 4.49E+05 - - - 6.2788 0.765 221125_WJC_METTL3_EV_vs_WT_F03.25136.25136.3 0.00617 Sep-72 K.KGPEPVPLEFIPAQGLLGR.P sp|Q9BVI4|NOC4L_HUMAN 1 2017.136 1.53 39430 25136 3 2017.142019 673.386 Nucleolar complex protein 4 homolog OS=Homo sapiens OX=9606 GN=NOC4L PE=1 SV=1 6.14 3853.5 - 229952 - - - 2.9606 - 2.165 0.274 - 67.1 1 1 0 0.006 19 0 0 0 1.32E+06 8.64E+05 - - - 3.4909 0.9983 221125_WJC_METTL3_EV_vs_WT_F03.25139.25139.3 9.68E-05 Sep-56 R.DNMSIVLVC[160.03]FSNAPK.V "sp|O75688|PPM1B_HUMAN,tr|A0A3B3IS24|A0A3B3IS24_HUMAN,tr|C9JIR6|C9JIR6_HUMAN" 3 1693.8168 2.61 39433 25139 3 1693.824685 565.6129 Protein phosphatase 1B OS=Homo sapiens OX=9606 GN=PPM1B PE=1 SV=1 5.83 3853.9 - 92692.2 - - - 4.677 - 1.591 0.464 - 105.2 1 2 0 0.0079 15 0 0 0 8.69E+05 3.33E+05 - - - 4.9226 0.9901 221125_WJC_METTL3_EV_vs_WT_F03.25144.25144.3 0.0125 Sep-56 K.VSQEILELLNTTTAK[136.11].E "sp|Q86U44|MTA70_HUMAN,tr|H0YFV6|H0YFV6_HUMAN" 2 1666.9233 0.05 39437 25144 3 1666.929269 556.6484 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 4.53 3854.5 - 127550 - - - 3.6006 - 1.669 0.276 - 67.8 1 2 0 0.006 15 0 0 0 1.08E+05 2.37E+06 - - - 2.952 1 221125_WJC_METTL3_EV_vs_WT_F03.25145.25145.3 3.24E-08 16/76 K.GYFNNNIPPVEFTQENPFC[160.03]R.F sp|Q7Z3B4|NUP54_HUMAN 1 2442.1063 2.53 39438 25145 3 2442.104699 815.0427 Nucleoporin p54 OS=Homo sapiens OX=9606 GN=NUP54 PE=1 SV=2 4.53 3854.6 - 1.08E+06 - - - -0.6474 - 3.424 0.555 - 285.3 1 2 0 -0.0016 20 0 0 0 1.01E+07 4.01E+06 - - - 7.7132 1 221125_WJC_METTL3_EV_vs_WT_F03.25146.25146.3 4.43E-12 22/88 K.LPSTGEGTQFYLFENVDNAQQFK.Q "sp|P30519|HMOX2_HUMAN,tr|I3L159|I3L159_HUMAN,tr|A0A087WT44|A0A087WT44_HUMAN,tr|I3L1F5|I3L1F5_HUMAN" 4 2632.2445 1.24 39439 25146 3 2632.245133 878.4221 Heme oxygenase 2 OS=Homo sapiens OX=9606 GN=HMOX2 PE=1 SV=2 4.14 3854.8 - 774841 - - - 0.2222 - 4.099 0.634 - 580.5 1 2 0 0.0006 23 0 0 0 6.17E+06 4.96E+06 - - - 8.9178 1 221125_WJC_METTL3_EV_vs_WT_F03.25149.25149.2 2.22E-09 14/34 G.FTPSLDSDFTFTLPAGQK[136.11].E "sp|Q9Y3A6|TMED5_HUMAN,tr|B1AKT3|B1AKT3_HUMAN,tr|M0R072|M0R072_HUMAN" 3 1978.9768 1.33 39442 25149 2 1978.973458 990.4957 Transmembrane emp24 domain-containing protein 5 OS=Homo sapiens OX=9606 GN=TMED5 PE=1 SV=1 4.21 3855.1 - 184162 - - - -1.668 - 2.858 0.68 - 323.4 1 1 0 -0.0033 18 0 0 0 3.80E+06 2.85E+06 - - - 6.6442 1 221125_WJC_METTL3_EV_vs_WT_F03.25150.25150.3 1.32E-07 13/84 K.DFMIQGGDFVNGDGTGVASIYR.G "sp|O43447|PPIH_HUMAN,tr|A0A7I2YQS4|A0A7I2YQS4_HUMAN,tr|C9JQD4|C9JQD4_HUMAN" 3 2318.0637 48.51 39443 25150 3 2318.066355 773.6952 Peptidyl-prolyl cis-trans isomerase H OS=Homo sapiens OX=9606 GN=PPIH PE=1 SV=1 3.93 3855.2 - 169663 - - - 1.1255 - 2.463 0.591 - 170 1 2 0 0.0026 22 0 0 0 3.34E+06 6.88E+04 - - - 7.2654 1 221125_WJC_METTL3_EV_vs_WT_F03.25154.25154.4 3.84E-05 30/132 R.GFGFVTYATVEEVDAAMNARPHK.V "sp|P09651|ROA1_HUMAN,tr|A0A7I2YQX9|A0A7I2YQX9_HUMAN,tr|A0A7I2V3W4|A0A7I2V3W4_HUMAN,tr|F8W646|F8W646_HUMAN,tr|F8VZ49|F8VZ49_HUMAN,tr|A0A7I2V3R8|A0A7I2V3R8_HUMAN,tr|F8W6I7|F8W6I7_HUMAN,tr|F8VYN5|F8VYN5_HUMAN,tr|A0A7I2V2L6|A0A7I2V2L6_HUMAN,tr|A0A7I2V3C7|A0A7I2V3C7_HUMAN,tr|A0A7I2V3W0|A0A7I2V3W0_HUMAN,tr|A0A7I2YQV3|A0A7I2YQV3_HUMAN,tr|A0A2R8Y4L2|A0A2R8Y4L2_HUMAN,tr|A0A7I2V2Z4|A0A7I2V2Z4_HUMAN,tr|A0A7I2V4M0|A0A7I2V4M0_HUMAN" 15 2509.206 1.27 39445 25154 4 2509.204395 628.3088 Heterogeneous nuclear ribonucleoprotein A1 OS=Homo sapiens OX=9606 GN=HNRNPA1 PE=1 SV=5 5.45 3855.8 - 9.74E+06 - - - -0.6373 - 5.086 0.558 - 614.5 1 2 0 -0.0016 23 0 0 0 1.22E+08 9.58E+07 - - - 4.6094 1 221125_WJC_METTL3_EV_vs_WT_F03.25155.25155.4 3.06E-12 27/132 R.GFGFVTYATVEEVDAAMNAR[166.11]PHK[136.11].V "sp|P09651|ROA1_HUMAN,tr|A0A7I2YQX9|A0A7I2YQX9_HUMAN,tr|A0A7I2V3W4|A0A7I2V3W4_HUMAN,tr|F8W646|F8W646_HUMAN,tr|F8VZ49|F8VZ49_HUMAN,tr|A0A7I2V3R8|A0A7I2V3R8_HUMAN,tr|F8W6I7|F8W6I7_HUMAN,tr|F8VYN5|F8VYN5_HUMAN,tr|A0A7I2V2L6|A0A7I2V2L6_HUMAN,tr|A0A7I2V3C7|A0A7I2V3C7_HUMAN,tr|A0A7I2V3W0|A0A7I2V3W0_HUMAN,tr|A0A7I2YQV3|A0A7I2YQV3_HUMAN,tr|A0A2R8Y4L2|A0A2R8Y4L2_HUMAN,tr|A0A7I2V2Z4|A0A7I2V2Z4_HUMAN,tr|A0A7I2V4M0|A0A7I2V4M0_HUMAN" 15 2527.2285 1.27 39446 25155 4 2527.22446 632.8144 Heterogeneous nuclear ribonucleoprotein A1 OS=Homo sapiens OX=9606 GN=HNRNPA1 PE=1 SV=5 5.45 3855.8 - 8.36E+06 - - - -1.5843 - 4.999 0.548 - 446.3 1 2 0 -0.004 23 0 0 0 1.22E+08 9.58E+07 - - - 4.5161 1 221125_WJC_METTL3_EV_vs_WT_F03.25156.25156.3 1.42E-09 19/88 K.LPSTGEGTQFYLFENVDNAQQFK[136.11].Q "sp|P30519|HMOX2_HUMAN,tr|I3L159|I3L159_HUMAN,tr|A0A087WT44|A0A087WT44_HUMAN,tr|I3L1F5|I3L1F5_HUMAN" 4 2640.2587 1.24 39447 25156 3 2640.259632 881.0935 Heme oxygenase 2 OS=Homo sapiens OX=9606 GN=HMOX2 PE=1 SV=2 4.14 3856 - 753526 - - - 0.3348 - 3.805 0.617 - 349.2 1 2 0 0.0009 23 0 0 0 6.17E+06 4.96E+06 - - - 8.5536 0.9999 221125_WJC_METTL3_EV_vs_WT_F03.25157.25157.3 3.51E-10 16/84 K.DGVFLYFEDNAGVIVNNK[136.11]GEMK[136.11].G "sp|P62829|RL23_HUMAN,tr|J3KT29|J3KT29_HUMAN,tr|J3KTJ3|J3KTJ3_HUMAN" 3 2474.2123 1.41 39448 25157 3 2474.218009 825.7447 60S ribosomal protein L23 OS=Homo sapiens OX=9606 GN=RPL23 PE=1 SV=1 4.32 3856.1 - 613528 - - - 2.3228 - 3.51 0.614 - 267.7 1 2 1 0.0057 22 0 0 0 5.53E+06 3.91E+06 - - - 8.3608 1 221125_WJC_METTL3_EV_vs_WT_F03.25162.25162.2 3.28E-11 14/30 K.GFDQTINLILDESHER.V "sp|O95777|LSM8_HUMAN,tr|C9JNV3|C9JNV3_HUMAN,tr|C9JIZ0|C9JIZ0_HUMAN,tr|F2Z2Y6|F2Z2Y6_HUMAN" 4 1885.917 -1 39453 25162 2 1885.916313 943.9658 U6 snRNA-associated Sm-like protein LSm8 OS=Homo sapiens OX=9606 GN=LSM8 PE=1 SV=3 4.31 3856.8 - 437811 - - - -0.3675 - 3.234 0.683 - 689.1 1 2 0 -0.0007 16 0 0 0 0.00E+00 0.00E+00 - - - 6.9711 1 221125_WJC_METTL3_EV_vs_WT_F03.25165.25165.3 2.67E-08 19/84 R.ELFEFVTDPSITHENMDAYLSK.A sp|Q9BRS2|RIOK1_HUMAN 1 2585.1996 2.69 39456 25165 3 2585.200864 862.7405 Serine\threonine-protein kinase RIO1 OS=Homo sapiens OX=9606 GN=RIOK1 PE=1 SV=2 4.17 3857.1 - 310257 - - - 0.5002 - 3.567 0.625 - 362.1 1 2 0 0.0013 22 0 0 0 1.68E+06 6.25E+05 - - - 8.5228 0.9944 221125_WJC_METTL3_EV_vs_WT_F03.25166.25166.3 4.37E-07 Dec-56 N.AQDIINFFAPLKPVR.L "sp|Q12849|GRSF1_HUMAN,tr|H0YAK1|H0YAK1_HUMAN,tr|H0Y8R1|H0Y8R1_HUMAN,tr|F5H5I6|F5H5I6_HUMAN" 4 1727.9723 1.21 39457 25166 3 1727.976336 576.998 G-rich sequence factor 1 OS=Homo sapiens OX=9606 GN=GRSF1 PE=1 SV=3 8.79 3857.3 - 269096 - - - 2.3496 - 2.285 0.559 - 134.6 1 1 0 0.0041 15 0 0 0 1.67E+06 1.37E+06 - - - 6.9275 1 221125_WJC_METTL3_EV_vs_WT_F03.25177.25177.3 4.28E-07 23/88 R.GFGFVTYATVEEVDAAMNARPHK.V "sp|P09651|ROA1_HUMAN,tr|A0A7I2YQX9|A0A7I2YQX9_HUMAN,tr|A0A7I2V3W4|A0A7I2V3W4_HUMAN,tr|F8W646|F8W646_HUMAN,tr|F8VZ49|F8VZ49_HUMAN,tr|A0A7I2V3R8|A0A7I2V3R8_HUMAN,tr|F8W6I7|F8W6I7_HUMAN,tr|F8VYN5|F8VYN5_HUMAN,tr|A0A7I2V2L6|A0A7I2V2L6_HUMAN,tr|A0A7I2V3C7|A0A7I2V3C7_HUMAN,tr|A0A7I2V3W0|A0A7I2V3W0_HUMAN,tr|A0A7I2YQV3|A0A7I2YQV3_HUMAN,tr|A0A2R8Y4L2|A0A2R8Y4L2_HUMAN,tr|A0A7I2V2Z4|A0A7I2V2Z4_HUMAN,tr|A0A7I2V4M0|A0A7I2V4M0_HUMAN" 15 2509.206 1.15 39466 25177 3 2509.206905 837.4093 Heterogeneous nuclear ribonucleoprotein A1 OS=Homo sapiens OX=9606 GN=HNRNPA1 PE=1 SV=5 5.45 3858.6 - 1.85E+06 - - - 0.3631 - 4.318 0.606 - 540.5 1 2 0 0.0009 23 0 0 0 1.85E+07 1.61E+07 - - - 8.7277 1 221125_WJC_METTL3_EV_vs_WT_F03.25178.25178.3 2.85E-08 20/88 R.QSLLGPPPVGVPMNPSQFNLSGR.N "sp|Q9ULV3|CIZ1_HUMAN,tr|Q5SYW2|Q5SYW2_HUMAN,tr|F5H2X7|F5H2X7_HUMAN,tr|H0Y5D5|H0Y5D5_HUMAN,tr|A0A494C0L7|A0A494C0L7_HUMAN,tr|Q9BTG3|Q9BTG3_HUMAN,tr|F6VD24|F6VD24_HUMAN" 7 2391.2369 2.17 39467 25178 3 2391.239069 798.0862 Cip1-interacting zinc finger protein OS=Homo sapiens OX=9606 GN=CIZ1 PE=1 SV=2 9.75 3858.7 - 822652 - - - 0.9071 - 3.7 0.616 - 346.7 1 2 0 0.0022 23 0 0 0 6.77E+06 3.11E+06 - - - 8.4765 1 221125_WJC_METTL3_EV_vs_WT_F03.25185.25185.2 1.35E-07 16/24 K.TLNDELEIIEGMK.F "sp|P10809|CH60_HUMAN,tr|A0A7I2V2X6|A0A7I2V2X6_HUMAN,tr|A0A7I2V599|A0A7I2V599_HUMAN,tr|E7EXB4|E7EXB4_HUMAN,tr|A0A7I2YQ71|A0A7I2YQ71_HUMAN,tr|E7ESH4|E7ESH4_HUMAN,tr|A0A7I2V5M1|A0A7I2V5M1_HUMAN,tr|A0A7I2V5K3|A0A7I2V5K3_HUMAN,tr|A0A7I2V369|A0A7I2V369_HUMAN" 9 1503.7491 1.24 39472 25185 2 1503.750419 752.8818 "60 kDa heat shock protein, mitochondrial OS=Homo sapiens OX=9606 GN=HSPD1 PE=1 SV=2" 4 3859.6 - 1.66E+06 - - - 0.9031 - 2.756 0.581 - 553.4 1 2 0 0.0014 13 0 0 0 4.91E+07 3.97E+07 - - - 5.9337 0.9998 221125_WJC_METTL3_EV_vs_WT_F03.25186.25186.2 1.78E-05 13/24 K.TLNDELEIIEGMK[136.11].F "sp|P10809|CH60_HUMAN,tr|A0A7I2V2X6|A0A7I2V2X6_HUMAN,tr|A0A7I2V599|A0A7I2V599_HUMAN,tr|E7EXB4|E7EXB4_HUMAN,tr|A0A7I2YQ71|A0A7I2YQ71_HUMAN,tr|E7ESH4|E7ESH4_HUMAN,tr|A0A7I2V5M1|A0A7I2V5M1_HUMAN,tr|A0A7I2V5K3|A0A7I2V5K3_HUMAN,tr|A0A7I2V369|A0A7I2V369_HUMAN" 9 1511.7633 1.24 39473 25186 2 1511.765568 756.8889 "60 kDa heat shock protein, mitochondrial OS=Homo sapiens OX=9606 GN=HSPD1 PE=1 SV=2" 4 3859.7 - 1.22E+06 - - - 1.526 - 2.453 0.51 - 347.5 1 2 0 0.0023 13 0 0 0 4.91E+07 3.97E+07 - - - 5.1101 1 221125_WJC_METTL3_EV_vs_WT_F03.25187.25187.3 6.57E-13 31/88 R.GFGFVTYATVEEVDAAMNAR[166.11]PHK[136.11].V "sp|P09651|ROA1_HUMAN,tr|A0A7I2YQX9|A0A7I2YQX9_HUMAN,tr|A0A7I2V3W4|A0A7I2V3W4_HUMAN,tr|F8W646|F8W646_HUMAN,tr|F8VZ49|F8VZ49_HUMAN,tr|A0A7I2V3R8|A0A7I2V3R8_HUMAN,tr|F8W6I7|F8W6I7_HUMAN,tr|F8VYN5|F8VYN5_HUMAN,tr|A0A7I2V2L6|A0A7I2V2L6_HUMAN,tr|A0A7I2V3C7|A0A7I2V3C7_HUMAN,tr|A0A7I2V3W0|A0A7I2V3W0_HUMAN,tr|A0A7I2YQV3|A0A7I2YQV3_HUMAN,tr|A0A2R8Y4L2|A0A2R8Y4L2_HUMAN,tr|A0A7I2V2Z4|A0A7I2V2Z4_HUMAN,tr|A0A7I2V4M0|A0A7I2V4M0_HUMAN" 15 2527.2285 1.13 39474 25187 3 2527.224595 843.4168 Heterogeneous nuclear ribonucleoprotein A1 OS=Homo sapiens OX=9606 GN=HNRNPA1 PE=1 SV=5 5.45 3859.8 - 1.12E+06 - - - -1.5309 - 5.653 0.691 - 1287.9 1 2 0 -0.0039 23 0 0 0 1.85E+07 1.64E+07 - - - 10.3065 1 221125_WJC_METTL3_EV_vs_WT_F03.25188.25188.3 0.000563 Dec-48 K.TLNDELEIIEGMK.F "sp|P10809|CH60_HUMAN,tr|A0A7I2V2X6|A0A7I2V2X6_HUMAN,tr|A0A7I2V599|A0A7I2V599_HUMAN,tr|E7EXB4|E7EXB4_HUMAN,tr|A0A7I2YQ71|A0A7I2YQ71_HUMAN,tr|E7ESH4|E7ESH4_HUMAN,tr|A0A7I2V5M1|A0A7I2V5M1_HUMAN,tr|A0A7I2V5K3|A0A7I2V5K3_HUMAN,tr|A0A7I2V369|A0A7I2V369_HUMAN" 9 1503.7491 1.29 39475 25188 3 1503.748659 502.257 "60 kDa heat shock protein, mitochondrial OS=Homo sapiens OX=9606 GN=HSPD1 PE=1 SV=2" 4 3859.9 - 513033 - - - -0.2673 - 2.156 0.489 - 274.6 1 2 0 -0.0004 13 0 0 0 6.00E+06 4.63E+06 - - - 6.0747 0.9999 221125_WJC_METTL3_EV_vs_WT_F03.25191.25191.3 0.000278 Nov-48 K.TLNDELEIIEGMK[136.11].F "sp|P10809|CH60_HUMAN,tr|A0A7I2V2X6|A0A7I2V2X6_HUMAN,tr|A0A7I2V599|A0A7I2V599_HUMAN,tr|E7EXB4|E7EXB4_HUMAN,tr|A0A7I2YQ71|A0A7I2YQ71_HUMAN,tr|E7ESH4|E7ESH4_HUMAN,tr|A0A7I2V5M1|A0A7I2V5M1_HUMAN,tr|A0A7I2V5K3|A0A7I2V5K3_HUMAN,tr|A0A7I2V369|A0A7I2V369_HUMAN" 9 1511.7633 1.29 39478 25191 3 1511.76355 504.9284 "60 kDa heat shock protein, mitochondrial OS=Homo sapiens OX=9606 GN=HSPD1 PE=1 SV=2" 4 3860.3 - 343126 - - - 0.1912 - 1.95 0.427 - 256.5 1 2 0 0.0003 13 0 0 0 6.00E+06 4.63E+06 - - - 5.1112 0.9998 221125_WJC_METTL3_EV_vs_WT_F03.25193.25193.3 2.33E-05 Oct-92 R.ALPWQLNDPNYFSIDAPPSFKPAK.K "sp|Q6PI98|IN80C_HUMAN,tr|M0R3E2|M0R3E2_HUMAN,tr|K7EIY8|K7EIY8_HUMAN" 3 2715.3697 1.12 39480 25193 3 2715.37262 906.1305 INO80 complex subunit C OS=Homo sapiens OX=9606 GN=INO80C PE=1 SV=1 6 3860.5 - 186737 - - - 1.0794 - 1.831 0.438 - 59.2 1 2 0 0.0029 24 0 0 0 2.35E+06 2.11E+06 - - - 4.8273 1 221125_WJC_METTL3_EV_vs_WT_F03.25194.25194.3 3.53E-09 24/60 R.LQQELDDLLVDLDHQR.Q sp|P35579|MYH9_HUMAN 1 1948.9854 0.97 39481 25194 3 1948.988914 650.6691 Myosin-9 OS=Homo sapiens OX=9606 GN=MYH9 PE=1 SV=4 4.03 3860.7 - 158759 - - - 1.7927 - 3.646 0.596 - 1027 1 2 0 0.0035 16 0 0 0 3.64E+07 3.75E+07 - - - 8.5031 1 221125_WJC_METTL3_EV_vs_WT_F03.25198.25198.3 0.000576 30/60 R.LQQELDDLLVDLDHQR[166.11].Q sp|P35579|MYH9_HUMAN 1 1958.9937 0.98 39483 25198 3 1958.992025 654.0052 Myosin-9 OS=Homo sapiens OX=9606 GN=MYH9 PE=1 SV=4 4.03 3861.2 - 3.58E+06 - - - -0.8499 - 4.249 0.58 - 1797.6 1 2 0 -0.0017 16 0 0 0 3.62E+07 3.69E+07 - - - 8.718 1 221125_WJC_METTL3_EV_vs_WT_F03.25203.25203.3 3.47E-11 21/84 R.TSSVPEYVYNLHLVENDFVGGR.S sp|Q99959|PKP2_HUMAN 1 2494.2129 1.7 39488 25203 3 2494.216527 832.4116 Plakophilin-2 OS=Homo sapiens OX=9606 GN=PKP2 PE=1 SV=2 4.65 3861.9 - 986850 - - - 1.4726 - 3.777 0.653 - 380.8 1 2 0 0.0037 22 0 0 0 4.12E+06 2.42E+06 - - - 8.97 0.9999 221125_WJC_METTL3_EV_vs_WT_F03.25205.25205.3 1.27E-09 16/76 K.NAISLPQLNQAAYDSLVVGK.L sp|Q00587|BORG5_HUMAN 1 2100.1215 3.59 39490 25205 3 2100.130023 701.0478 Cdc42 effector protein 1 OS=Homo sapiens OX=9606 GN=CDC42EP1 PE=1 SV=1 5.83 3862.1 - 659114 - - - 4.0493 - 3.415 0.585 - 353.6 1 2 0 0.0085 20 0 0 0 7.00E+06 1.95E+06 - - - 8.0394 0.9998 221125_WJC_METTL3_EV_vs_WT_F03.25206.25206.3 2.09E-05 Oct-88 R.LTLAPVYTSPQLDMSC[160.03]PLLQQNK.Q sp|Q8TEM1|PO210_HUMAN 1 2616.3291 1.23 39491 25206 3 2616.334608 873.117 Nuclear pore membrane glycoprotein 210 OS=Homo sapiens OX=9606 GN=NUP210 PE=1 SV=3 5.83 3862.3 - 637508 - - - 2.0877 - 2.254 0.447 - 73.2 1 2 0 0.0055 23 0 0 0 5.10E+06 4.13E+06 - - - 5.4287 0.9993 221125_WJC_METTL3_EV_vs_WT_F03.25208.25208.3 3.44E-09 14/64 R.QHFPATPLLDYALEVEK[136.11].L sp|P53396|ACLY_HUMAN 1 1978.0291 0.99 39493 25208 3 1978.041638 660.3503 ATP-citrate synthase OS=Homo sapiens OX=9606 GN=ACLY PE=1 SV=3 4.65 3862.5 - 460856 - - - 6.324 - 2.996 0.529 - 288.8 1 2 0 0.0125 17 0 0 0 4.94E+06 4.99E+06 - - - 7.2064 0.9999 221125_WJC_METTL3_EV_vs_WT_F03.25210.25210.3 4.00E-08 14/68 K.VAHNILSGASWVSWGLVK.G sp|Q8N0X7|SPART_HUMAN 1 1923.0367 0.56 39495 25210 3 1923.04331 642.0195 Spartin OS=Homo sapiens OX=9606 GN=SPART PE=1 SV=1 8.73 3862.8 - 390413 - - - 3.4544 - 2.777 0.518 - 197.1 1 2 0 0.0066 18 0 0 0 1.12E+06 2.00E+06 - - - 6.8567 0.9969 221125_WJC_METTL3_EV_vs_WT_F03.25211.25211.3 6.16E-05 Oct-56 R.LKDLDLDAFAEELER.Q sp|Q7KZ85|SPT6H_HUMAN 1 1775.8941 0.85 39496 25211 3 1775.899645 592.972 Transcription elongation factor SPT6 OS=Homo sapiens OX=9606 GN=SUPT6H PE=1 SV=2 4.02 3862.9 - 380344 - - - 3.097 - 2.065 0.386 - 148 1 2 1 0.0055 15 0 0 0 1.36E+06 1.60E+06 - - - 4.7341 1 221125_WJC_METTL3_EV_vs_WT_F03.25213.25213.2 1.30E-07 30-Dec K.ITISSLQDLTLYNPER[166.11].T sp|Q9NZI8|IF2B1_HUMAN 1 1871.9868 -1 39498 25213 2 1871.989516 937.0007 Insulin-like growth factor 2 mRNA-binding protein 1 OS=Homo sapiens OX=9606 GN=IGF2BP1 PE=1 SV=2 4.37 3863.2 - 302958 - - - 1.4439 - 2.842 0.639 - 625.5 1 2 0 0.0027 16 0 0 0 0.00E+00 0.00E+00 - - - 6.3278 1 221125_WJC_METTL3_EV_vs_WT_F03.25214.25214.2 0.00101 20/30 R.LQQELDDLLVDLDHQR[166.11].Q sp|P35579|MYH9_HUMAN 1 1958.9937 1.08 39499 25214 2 1958.994943 980.5041 Myosin-9 OS=Homo sapiens OX=9606 GN=MYH9 PE=1 SV=4 4.03 3863.3 - 293593 - - - 0.6396 - 3.703 0.58 - 1571.7 1 2 0 0.0013 16 0 0 0 4.32E+06 4.00E+06 - - - 6.5431 1 221125_WJC_METTL3_EV_vs_WT_F03.25216.25216.2 1.11E-10 21/30 R.LQQELDDLLVDLDHQR.Q sp|P35579|MYH9_HUMAN 1 1948.9854 1.08 39501 25216 2 1948.993679 975.5 Myosin-9 OS=Homo sapiens OX=9606 GN=MYH9 PE=1 SV=4 4.03 3863.6 - 207274 - - - 4.2376 - 3.755 0.598 - 1868.5 1 2 0 0.0083 16 0 0 0 4.32E+06 4.00E+06 - - - 6.7081 1 221125_WJC_METTL3_EV_vs_WT_F03.25218.25218.3 3.95E-13 16/100 K.NAFPLGAPTLVTSQATTLSTFQPANK.L "sp|Q8IWZ3|ANKH1_HUMAN,tr|A0A0A0MQZ8|A0A0A0MQZ8_HUMAN,tr|H0Y472|H0Y472_HUMAN,tr|H0Y7Y3|H0Y7Y3_HUMAN,tr|H0Y4P6|H0Y4P6_HUMAN,tr|H0Y785|H0Y785_HUMAN" 6 2674.3966 2.03 39502 25218 3 2674.398755 892.4728 Ankyrin repeat and KH domain-containing protein 1 OS=Homo sapiens OX=9606 GN=ANKHD1 PE=1 SV=1 8.75 3863.8 - 1.02E+06 - - - 0.7938 - 3.481 0.658 - 164.6 1 2 0 0.0021 26 0 0 0 2.08E+07 1.02E+07 - - - 8.7451 1 221125_WJC_METTL3_EV_vs_WT_F03.25221.25221.3 1.80E-10 20/60 R.KLTFLYLANDVIQNSK.R "sp|Q96P16|RPR1A_HUMAN,sp|Q9NQG5|RPR1B_HUMAN,tr|E9PIQ9|E9PIQ9_HUMAN,tr|A0A0C4DGQ6|A0A0C4DGQ6_HUMAN" 4 1866.0251 2.91 39505 25221 3 1866.027473 623.0156 Regulation of nuclear pre-mRNA domain-containing protein 1A OS=Homo sapiens OX=9606 GN=RPRD1A PE=1 SV=1 8.5 3864 - 4.35E+06 - - - 1.2717 - 3.48 0.544 - 710.8 1 2 0 0.0024 16 0 0 0 1.88E+07 6.46E+06 - - - 7.8041 1 221125_WJC_METTL3_EV_vs_WT_F03.25224.25224.3 1.78E-11 25/92 Q.QVFDNGSIYNPEVLDITEETLHSR.F "sp|P05388|RLA0_HUMAN,tr|F8VU65|F8VU65_HUMAN,tr|F8VW21|F8VW21_HUMAN,tr|F8VZS0|F8VZS0_HUMAN" 4 2775.3352 1.09 39508 25224 3 2775.331796 926.119 60S acidic ribosomal protein P0 OS=Homo sapiens OX=9606 GN=RPLP0 PE=1 SV=1 4.17 3864.4 - 1.62E+06 - - - -1.2099 - 4.633 0.667 - 761.9 1 1 0 -0.0034 24 0 0 0 4.23E+06 3.90E+06 - - - 9.5365 1 221125_WJC_METTL3_EV_vs_WT_F03.25225.25225.3 2.30E-08 29/88 R.LHLSGIDANPNALFPPVEFPAPR.G "sp|P49327|FAS_HUMAN,tr|A0A0U1RQF0|A0A0U1RQF0_HUMAN" 2 2471.2961 0.75 39509 25225 3 2471.29722 824.7727 Fatty acid synthase OS=Homo sapiens OX=9606 GN=FASN PE=1 SV=3 5.32 3864.6 - 1.45E+06 - - - 0.4411 - 4.712 0.661 - 806.5 1 2 0 0.0011 23 0 0 0 6.95E+06 9.26E+06 - - - 9.5457 1 221125_WJC_METTL3_EV_vs_WT_F03.25227.25227.2 1.68E-05 22-Nov R.AQFEGIVTDLIR[166.11].R "sp|P38646|GRP75_HUMAN,tr|H0Y8K0|H0Y8K0_HUMAN,tr|A0A7I2V2S7|A0A7I2V2S7_HUMAN,tr|A0A7I2V2G2|A0A7I2V2G2_HUMAN,tr|A0A7I2V3F7|A0A7I2V3F7_HUMAN,tr|A0A7I2YQB2|A0A7I2YQB2_HUMAN,tr|D6RCD7|D6RCD7_HUMAN" 7 1370.7433 0.73 39511 25227 2 1370.745485 686.3789 "Stress-70 protein, mitochondrial OS=Homo sapiens OX=9606 GN=HSPA9 PE=1 SV=2" 4.37 3864.8 - 896275 - - - 1.5685 - 2.53 0.595 - 476 1 2 0 0.0022 12 0 0 0 3.27E+06 4.47E+06 - - - 5.8773 0.9999 221125_WJC_METTL3_EV_vs_WT_F03.25229.25229.2 6.36E-08 30-Oct K.ITISSLQDLTLYNPER.T sp|Q9NZI8|IF2B1_HUMAN 1 1861.9785 1.6 39513 25229 2 1861.977373 931.9965 Insulin-like growth factor 2 mRNA-binding protein 1 OS=Homo sapiens OX=9606 GN=IGF2BP1 PE=1 SV=2 4.37 3865.1 - 561134 - - - -0.6284 - 2.618 0.546 - 296.3 1 2 0 -0.0012 16 0 0 0 3.11E+06 1.94E+06 - - - 5.4395 1 221125_WJC_METTL3_EV_vs_WT_F03.25231.25231.2 1.22E-09 Nov-32 R.MQLSAELQSDTEEILSK.A sp|O75643|U520_HUMAN 1 1920.935 -1 39515 25231 2 1920.936181 961.4748 U5 small nuclear ribonucleoprotein 200 kDa helicase OS=Homo sapiens OX=9606 GN=SNRNP200 PE=1 SV=2 4 3865.4 - 452073 - - - 0.6023 - 2.659 0.64 - 237.3 1 2 0 0.0012 17 0 0 0 0.00E+00 0.00E+00 - - - 6.172 0.9998 221125_WJC_METTL3_EV_vs_WT_F03.25240.25240.2 4.68E-05 22-Jul R.LFPPQWIC[160.03]C[160.03]DIR[166.11].Y sp|Q86U44|MTA70_HUMAN 1 1613.7722 0.001 39522 25240 2 1613.772388 807.8934 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 5.82 3866.5 - 373584 - - - 0.1103 - 1.77 0.493 - 129.5 1 2 0 0.0002 12 0 0 0 0.00E+00 5.33E+06 - - - 4.1846 1 221125_WJC_METTL3_EV_vs_WT_F03.25241.25241.3 1.25E-05 15/64 R.ELQAQIAELQEDFESEK.A sp|P35580|MYH10_HUMAN 1 2005.948 1.25 39523 25241 3 2005.950337 669.6566 Myosin-10 OS=Homo sapiens OX=9606 GN=MYH10 PE=1 SV=3 3.83 3866.6 - 329094 - - - 1.1496 - 2.94 0.462 - 315.1 1 2 0 0.0023 17 0 0 0 1.25E+07 1.00E+07 - - - 6.4146 1 221125_WJC_METTL3_EV_vs_WT_F03.25247.25247.3 1.39E-10 22/80 R.VAEEHAPSIVFIDEIDAIGTK.R sp|P62191|PRS4_HUMAN 1 2253.1529 0.84 39527 25247 3 2253.156929 752.0582 26S proteasome regulatory subunit 4 OS=Homo sapiens OX=9606 GN=PSMC1 PE=1 SV=1 4.17 3867.4 - 921401 - - - 1.7975 - 4.132 0.577 - 783.5 1 2 0 0.004 21 0 0 0 1.10E+07 1.30E+07 - - - 8.3733 1 221125_WJC_METTL3_EV_vs_WT_F03.25248.25248.3 6.83E-10 20/80 R.VAEEHAPSIVFIDEIDAIGTK[136.11].R sp|P62191|PRS4_HUMAN 1 2261.1671 0.78 39528 25248 3 2261.171497 754.7296 26S proteasome regulatory subunit 4 OS=Homo sapiens OX=9606 GN=PSMC1 PE=1 SV=1 4.17 3867.5 - 1.28E+06 - - - 1.9539 - 3.873 0.59 - 579.6 1 2 0 0.0044 21 0 0 0 9.91E+06 1.27E+07 - - - 8.3629 0.9999 221125_WJC_METTL3_EV_vs_WT_F03.25250.25250.3 3.21E-08 17/64 R.ELQAQIAELQEDFESEK[136.11].A sp|P35580|MYH10_HUMAN 1 2013.9622 1.24 39530 25250 3 2013.956146 672.328 Myosin-10 OS=Homo sapiens OX=9606 GN=MYH10 PE=1 SV=3 3.83 3867.8 - 535266 - - - -3.0214 - 3.209 0.547 - 432 1 2 0 -0.0061 17 0 0 0 1.24E+07 1.00E+07 - - - 7.5824 0.9999 221125_WJC_METTL3_EV_vs_WT_F03.25252.25252.3 7.26E-08 16/88 R.GGPPFAFVEFEDPR[166.11]DAEDAVYGR[166.11].D "sp|Q07955|SRSF1_HUMAN,tr|J3KTL2|J3KTL2_HUMAN" 2 2560.1774 1.05 39532 25252 3 2560.180906 854.3997 Serine\arginine-rich splicing factor 1 OS=Homo sapiens OX=9606 GN=SRSF1 PE=1 SV=2 4.02 3868 - 403312 - - - 1.3858 - 2.924 0.54 - 116.1 1 2 1 0.0035 23 0 0 0 1.05E+07 1.00E+07 - - - 7.0766 1 221125_WJC_METTL3_EV_vs_WT_F03.25253.25253.2 4.86E-09 28-Dec K.QPEDDLGFDPFDVTR[166.11].K sp|O95628|CNOT4_HUMAN 1 1759.7929 2.42 39533 25253 2 1759.780393 880.9037 CCR4-NOT transcription complex subunit 4 OS=Homo sapiens OX=9606 GN=CNOT4 PE=1 SV=3 3.71 3868.2 - 377687 - - - -7.0872 - 2.355 0.637 - 297 1 2 0 -0.0125 15 0 0 0 1.09E+07 4.50E+06 - - - 5.8478 1 221125_WJC_METTL3_EV_vs_WT_F03.25258.25258.3 2.75E-09 16/80 R.GLPGDVTNQEVHDLLSDYELK[136.11].Y "sp|Q8IY67|RAVR1_HUMAN,tr|K7EKR9|K7EKR9_HUMAN,tr|E9PAU2|E9PAU2_HUMAN,tr|A0A087WZ13|A0A087WZ13_HUMAN" 4 2349.158 1.09 39536 25258 3 2349.157562 784.0599 Ribonucleoprotein PTB-binding 1 OS=Homo sapiens OX=9606 GN=RAVER1 PE=1 SV=1 4.1 3868.9 - 1.77E+06 - - - -0.1741 - 3.497 0.61 - 242.4 1 2 0 -0.0004 21 0 0 0 1.30E+08 1.19E+08 - - - 8.3422 1 221125_WJC_METTL3_EV_vs_WT_F03.25260.25260.3 1.92E-07 23/80 R.GLPGDVTNQEVHDLLSDYELK.Y "sp|Q8IY67|RAVR1_HUMAN,tr|K7EKR9|K7EKR9_HUMAN,tr|E9PAU2|E9PAU2_HUMAN,tr|A0A087WZ13|A0A087WZ13_HUMAN" 4 2341.1438 1.08 39538 25260 3 2341.14458 781.3885 Ribonucleoprotein PTB-binding 1 OS=Homo sapiens OX=9606 GN=RAVER1 PE=1 SV=1 4.1 3869.1 - 1.59E+06 - - - 0.3456 - 3.94 0.599 - 521.2 1 2 0 0.0008 21 0 0 0 1.29E+08 1.19E+08 - - - 8.5054 1 221125_WJC_METTL3_EV_vs_WT_F03.25262.25262.3 1.55E-15 23/120 K.AFLADPSAFVAAAPVAAATTAAPAAAAAPAK.V "sp|P05388|RLA0_HUMAN,tr|F8VWS0|F8VWS0_HUMAN,tr|F8W1K8|F8W1K8_HUMAN" 3 2751.4596 1.38 39540 25262 3 2751.462356 918.1605 60S acidic ribosomal protein P0 OS=Homo sapiens OX=9606 GN=RPLP0 PE=1 SV=1 5.88 3869.3 - 464527 - - - 1.014 - 4.857 0.656 - 448.8 1 2 0 0.0028 31 0 0 0 1.47E+08 1.07E+08 - - - 9.489 1 221125_WJC_METTL3_EV_vs_WT_F03.25266.25266.2 4.62E-12 17/34 K.ELYELWEEYETQSSAEAK.F sp|Q7Z4H3|HDDC2_HUMAN 1 2203.9797 7.52 39544 25266 2 2203.983799 1102.9971 5'-deoxynucleotidase HDDC2 OS=Homo sapiens OX=9606 GN=HDDC2 PE=1 SV=1 3.9 3869.8 - 186994 - - - 1.8485 - 3.445 0.742 - 969.1 1 2 0 0.0041 18 0 0 0 3.73E+06 4.96E+05 - - - 7.5612 1 221125_WJC_METTL3_EV_vs_WT_F03.25273.25273.2 5.63E-08 15/26 L.GENVTIESVADYFK[136.11].Q "sp|P35637|FUS_HUMAN,tr|H3BPE7|H3BPE7_HUMAN" 2 1578.7657 1.26 39549 25273 2 1578.767017 790.3901 RNA-binding protein FUS OS=Homo sapiens OX=9606 GN=FUS PE=1 SV=1 4.14 3870.8 - 686471 - - - 0.8323 - 2.943 0.618 - 906.9 1 1 0 0.0013 14 0 0 0 8.21E+06 6.52E+06 - - - 6.3139 1 221125_WJC_METTL3_EV_vs_WT_F03.25274.25274.3 1.44E-08 15/96 R.GVIINTASVAAFEGQVGQAAYSASK[136.11].G "sp|Q99714|HCD2_HUMAN,tr|A0A804HHW5|A0A804HHW5_HUMAN" 2 2446.2584 0.66 39550 25274 3 2446.262242 816.4267 3-hydroxyacyl-CoA dehydrogenase type-2 OS=Homo sapiens OX=9606 GN=HSD17B10 PE=1 SV=3 6 3870.9 - 552877 - - - 1.5894 - 2.978 0.569 - 197.1 1 2 0 0.0039 25 0 0 0 5.74E+06 8.69E+06 - - - 7.3933 1 221125_WJC_METTL3_EV_vs_WT_F03.25275.25275.3 5.13E-07 22/64 K.LNDLEEALQQAKEDLAR.L sp|P35908|K22E_HUMAN 1 1954.996 3.18 39551 25275 3 1954.985843 652.6726 "Keratin, type II cytoskeletal 2 epidermal OS=Homo sapiens OX=9606 GN=KRT2 PE=1 SV=2" 4.18 3871.1 - 498190 - - - -5.1872 - 4.679 0.568 - 834.7 1 2 1 -0.0101 17 0 0 0 2.47E+07 7.76E+06 - - - 8.7681 1 221125_WJC_METTL3_EV_vs_WT_F03.25276.25276.3 3.58E-06 17/60 K.QQPPAVQFVPPLPEWK.T "sp|O60341|KDM1A_HUMAN,tr|R4GMQ1|R4GMQ1_HUMAN,tr|R4GMP9|R4GMP9_HUMAN" 3 1859.9934 2.17 39552 25276 3 1859.994265 621.0051 Lysine-specific histone demethylase 1A OS=Homo sapiens OX=9606 GN=KDM1A PE=1 SV=2 6 3871.2 - 455518 - - - 0.4618 - 2.837 0.445 - 324.3 1 2 0 0.0009 16 0 0 0 9.43E+06 4.34E+06 - - - 6.1766 0.9999 221125_WJC_METTL3_EV_vs_WT_F03.25277.25277.4 2.97E-08 23/108 R.ADLEMQIENLKEELAYLKK.N "sp|Q04695|K1C17_HUMAN,tr|K7EPJ9|K7EPJ9_HUMAN,tr|F5GWP8|F5GWP8_HUMAN" 3 2277.1926 999 39553 25277 4 2277.193544 570.3054 "Keratin, type I cytoskeletal 17 OS=Homo sapiens OX=9606 GN=KRT17 PE=1 SV=2" 4.59 3871.3 - 396546 - - - 0.3992 - 4.52 0.549 - 523.4 1 2 1 0.0009 19 0 0 0 6.79E+07 0.00E+00 - - - 4.5145 0.9999 221125_WJC_METTL3_EV_vs_WT_F03.25281.25281.2 5.95E-07 13/36 R.GEELGGGQDPVQLLSGFPR.R "sp|Q04323|UBXN1_HUMAN,tr|A0A087WTZ5|A0A087WTZ5_HUMAN,tr|E9PJ81|E9PJ81_HUMAN,tr|E9PRQ7|E9PRQ7_HUMAN" 4 1954.9749 0.91 39557 25281 2 1954.97621 978.4947 UBX domain-containing protein 1 OS=Homo sapiens OX=9606 GN=UBXN1 PE=1 SV=2 4.14 3871.8 - 170034 - - - 0.6931 - 2.266 0.534 - 328.7 1 2 0 0.0014 19 0 0 0 4.62E+06 5.09E+06 - - - 4.9958 0.9999 221125_WJC_METTL3_EV_vs_WT_F03.25282.25282.3 6.10E-06 Aug-56 R.DNSVFHVSNLEFPFR.K sp|O60942|MCE1_HUMAN 1 1806.8689 1.11 39558 25282 3 1806.866873 603.2969 mRNA-capping enzyme OS=Homo sapiens OX=9606 GN=RNGTT PE=1 SV=1 5.32 3872 - 152455 - - - -1.1401 - 2.043 0.439 - 88.7 1 2 0 -0.0021 15 0 0 0 1.30E+06 1.17E+06 - - - 5.298 0.917 221125_WJC_METTL3_EV_vs_WT_F03.25283.25283.3 0.00171 Jul-52 L.GENVTIESVADYFK.Q "sp|P35637|FUS_HUMAN,tr|H3BPE7|H3BPE7_HUMAN" 2 1570.7515 0.39 39559 25283 3 1570.753961 524.5911 RNA-binding protein FUS OS=Homo sapiens OX=9606 GN=FUS PE=1 SV=1 4.14 3872.1 - 73386.1 - - - 1.5649 - 1.429 0.379 - 53.8 1 1 0 0.0025 14 0 0 0 4.50E+05 1.17E+06 - - - 3.7135 1 221125_WJC_METTL3_EV_vs_WT_F03.25286.25286.4 1.09E-13 28/180 K.AFLADPSAFVAAAPVAAATTAAPAAAAAPAK.V "sp|P05388|RLA0_HUMAN,tr|F8VWS0|F8VWS0_HUMAN,tr|F8W1K8|F8W1K8_HUMAN" 3 2751.4596 1.43 39560 25286 4 2751.467047 688.8722 60S acidic ribosomal protein P0 OS=Homo sapiens OX=9606 GN=RPLP0 PE=1 SV=1 5.88 3872.5 - 924088 - - - 2.7189 - 5.597 0.66 - 376.4 1 2 0 0.0075 31 0 0 0 2.61E+07 1.83E+07 - - - 5.492 0.9996 221125_WJC_METTL3_EV_vs_WT_F03.25288.25288.2 3.65E-07 Aug-40 R.GLPGDVTNQEVHDLLSDYELK[136.11].Y "sp|Q8IY67|RAVR1_HUMAN,tr|K7EKR9|K7EKR9_HUMAN,tr|E9PAU2|E9PAU2_HUMAN,tr|A0A087WZ13|A0A087WZ13_HUMAN" 4 2349.158 1.34 39562 25288 2 2349.151306 1175.5863 Ribonucleoprotein PTB-binding 1 OS=Homo sapiens OX=9606 GN=RAVER1 PE=1 SV=1 4.1 3872.6 - 3.22E+06 - - - -2.8372 - 2.11 0.603 - 103.4 1 2 0 -0.0067 21 0 0 0 1.67E+07 1.24E+07 - - - 5.3284 1 221125_WJC_METTL3_EV_vs_WT_F03.25289.25289.2 3.25E-07 Nov-40 R.GLPGDVTNQEVHDLLSDYELK.Y "sp|Q8IY67|RAVR1_HUMAN,tr|K7EKR9|K7EKR9_HUMAN,tr|E9PAU2|E9PAU2_HUMAN,tr|A0A087WZ13|A0A087WZ13_HUMAN" 4 2341.1438 1.34 39563 25289 2 2341.139275 1171.5792 Ribonucleoprotein PTB-binding 1 OS=Homo sapiens OX=9606 GN=RAVER1 PE=1 SV=1 4.1 3872.7 - 2.93E+06 - - - -1.9204 - 2.325 0.626 - 238.1 1 2 0 -0.0045 21 0 0 0 1.67E+07 1.24E+07 - - - 5.7375 1 221125_WJC_METTL3_EV_vs_WT_F03.25290.25290.3 7.96E-16 30/96 K.AGIEAGNINITSGEVFEIEEHISER.Q sp|O43172|PRP4_HUMAN 1 2713.3195 3.46 39564 25290 3 2713.314598 905.4471 U4\U6 small nuclear ribonucleoprotein Prp4 OS=Homo sapiens OX=9606 GN=PRPF4 PE=1 SV=2 4.2 3872.8 - 1.71E+06 - - - -1.8081 - 5.656 0.685 - 1273.1 1 2 0 -0.0049 25 0 0 0 3.38E+07 9.77E+06 - - - 10.1621 1 221125_WJC_METTL3_EV_vs_WT_F03.25291.25291.2 4.26E-06 16/32 R.ELQAQIAELQEDFESEK.A sp|P35580|MYH10_HUMAN 1 2005.948 1.36 39565 25291 2 2005.94794 1003.9813 Myosin-10 OS=Homo sapiens OX=9606 GN=MYH10 PE=1 SV=3 3.83 3872.9 - 1.49E+06 - - - -0.0454 - 3.318 0.614 - 748.9 1 2 0 -0.0001 17 0 0 0 4.04E+06 2.97E+06 - - - 6.5247 0.9998 221125_WJC_METTL3_EV_vs_WT_F03.25293.25293.3 0.0825 Aug-56 K.ITPENLPQILLQLKR.R "sp|P43243|MATR3_HUMAN,tr|A8MXP9|A8MXP9_HUMAN,tr|D6R991|D6R991_HUMAN,tr|A0A0R4J2E8|A0A0R4J2E8_HUMAN,tr|D6REM6|D6REM6_HUMAN" 5 1775.0669 1.25 39567 25293 3 1775.064035 592.6962 Matrin-3 OS=Homo sapiens OX=9606 GN=MATR3 PE=1 SV=2 8.75 3873.1 - 1.26E+06 - - - -1.6168 - 1.771 0.42 - 73 1 2 0 -0.0029 15 0 0 0 1.71E+07 1.36E+07 - - - 4.7132 0.9998 221125_WJC_METTL3_EV_vs_WT_F03.25294.25294.2 2.71E-07 28-Dec K.VSQEILELLNTTTAK[136.11].E "sp|Q86U44|MTA70_HUMAN,tr|H0YFV6|H0YFV6_HUMAN" 2 1666.9233 0.001 39568 25294 2 1666.919933 834.4689 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 4.53 3873.2 - 1.22E+06 - - - -2.0001 - 2.631 0.567 - 587.3 1 2 0 -0.0033 15 0 0 0 0.00E+00 4.75E+06 - - - 5.6061 1 221125_WJC_METTL3_EV_vs_WT_F03.25296.25296.3 3.57E-08 Dec-56 K.ITPENLPQILLQLK[136.11]R[166.11].R "sp|P43243|MATR3_HUMAN,tr|A8MXP9|A8MXP9_HUMAN,tr|D6R991|D6R991_HUMAN,tr|A0A0R4J2E8|A0A0R4J2E8_HUMAN,tr|D6REM6|D6REM6_HUMAN" 5 1793.0894 1.26 39570 25296 3 1793.087323 598.7037 Matrin-3 OS=Homo sapiens OX=9606 GN=MATR3 PE=1 SV=2 8.75 3873.3 - 1.08E+06 - - - -1.1444 - 2.464 0.579 - 200.4 1 2 0 -0.0021 15 0 0 0 1.70E+07 1.35E+07 - - - 7.3478 1 221125_WJC_METTL3_EV_vs_WT_F03.25297.25297.2 8.45E-13 15/36 R.GEELGGGQDPVQLLSGFPR[166.11].R "sp|Q04323|UBXN1_HUMAN,tr|A0A087WTZ5|A0A087WTZ5_HUMAN,tr|E9PJ81|E9PJ81_HUMAN,tr|E9PRQ7|E9PRQ7_HUMAN" 4 1964.9831 0.91 39571 25297 2 1964.976364 983.4988 UBX domain-containing protein 1 OS=Homo sapiens OX=9606 GN=UBXN1 PE=1 SV=2 4.14 3873.5 - 497754 - - - -3.4407 - 3.378 0.717 - 562.9 1 2 0 -0.0068 19 0 0 0 4.62E+06 5.09E+06 - - - 7.3274 0.9991 221125_WJC_METTL3_EV_vs_WT_F03.25298.25298.2 0.0179 30-Jul K.QQPPAVQFVPPLPEWK[136.11].T "sp|O60341|KDM1A_HUMAN,tr|R4GMQ1|R4GMQ1_HUMAN,tr|R4GMP9|R4GMP9_HUMAN" 3 1868.0076 1.82 39572 25298 2 1868.009426 935.0111 Lysine-specific histone demethylase 1A OS=Homo sapiens OX=9606 GN=KDM1A PE=1 SV=2 6 3873.6 - 273830 - - - 0.9743 - 1.523 0.363 - 105.4 1 2 0 0.0018 16 0 0 0 3.48E+06 1.91E+06 - - - 2.7558 0.9981 221125_WJC_METTL3_EV_vs_WT_F03.25302.25302.3 7.61E-08 22/60 V.RQNLEPLFEQYINNLR.R "sp|P48668|K2C6C_HUMAN,sp|P04259|K2C6B_HUMAN,sp|P13647|K2C5_HUMAN,sp|P02538|K2C6A_HUMAN,tr|F8W0C6|F8W0C6_HUMAN" 5 2046.0647 999 39574 25302 3 2046.068805 683.0288 "Keratin, type II cytoskeletal 6C OS=Homo sapiens OX=9606 GN=KRT6C PE=1 SV=3" 6.14 3874.2 - 580873 - - - 2.0195 - 4.567 0.538 - 791 1 1 0 0.0041 16 0 0 0 1.68E+07 0.00E+00 - - - 8.4342 1 221125_WJC_METTL3_EV_vs_WT_F03.25304.25304.3 3.83E-11 16/72 R.GEELGGGQDPVQLLSGFPR[166.11].R "sp|Q04323|UBXN1_HUMAN,tr|A0A087WTZ5|A0A087WTZ5_HUMAN,tr|E9PJ81|E9PJ81_HUMAN,tr|E9PRQ7|E9PRQ7_HUMAN" 4 1964.9831 0.79 39576 25304 3 1964.988015 656.0017 UBX domain-containing protein 1 OS=Homo sapiens OX=9606 GN=UBXN1 PE=1 SV=2 4.14 3874.4 - 434035 - - - 2.4886 - 3.255 0.617 - 316.4 1 2 0 0.0049 19 0 0 0 7.09E+06 8.96E+06 - - - 8.3171 1 221125_WJC_METTL3_EV_vs_WT_F03.25307.25307.2 6.21E-12 18/36 K.SEIIPMFSNLASDEQDSVR[166.11].L "sp|P30153|2AAA_HUMAN,tr|C9J9C1|C9J9C1_HUMAN,tr|B3KQV6|B3KQV6_HUMAN" 3 2147.008 0.11 39579 25307 2 2147.009001 1074.5113 Serine\threonine-protein phosphatase 2A 65 kDa regulatory subunit A alpha isoform OS=Homo sapiens OX=9606 GN=PPP2R1A PE=1 SV=4 3.92 3874.8 - 325107 - - - 0.4574 - 3.197 0.715 - 852.8 1 2 0 0.001 19 0 0 0 6.90E+05 6.49E+06 - - - 7.179 1 221125_WJC_METTL3_EV_vs_WT_F03.25309.25309.3 2.62E-11 22/68 K.K[136.11]IEDLGAAMEEALILDNK[136.11].Y "sp|Q13813|SPTN1_HUMAN,tr|A0A0D9SF54|A0A0D9SF54_HUMAN,tr|A0A0D9SGF6|A0A0D9SGF6_HUMAN" 3 1988.0471 2.67 39581 25309 3 1988.048931 663.6896 "Spectrin alpha chain, non-erythrocytic 1 OS=Homo sapiens OX=9606 GN=SPTAN1 PE=1 SV=3" 4.18 3875.1 - 160950 - - - 0.924 - 3.799 0.666 - 830.2 1 2 0 0.0018 18 0 0 0 1.00E+07 3.76E+06 - - - 9.2884 0.9934 221125_WJC_METTL3_EV_vs_WT_F03.25310.25310.2 0.0177 30-Jul K.QQPPAVQFVPPLPEWK[136.11].T "sp|O60341|KDM1A_HUMAN,tr|R4GMQ1|R4GMQ1_HUMAN,tr|R4GMP9|R4GMP9_HUMAN" 3 1868.0076 1.82 39582 25310 2 1868.01233 935.0111 Lysine-specific histone demethylase 1A OS=Homo sapiens OX=9606 GN=KDM1A PE=1 SV=2 6 3875.2 - 158779 - - - 2.5289 - 1.376 0.266 - 106.8 1 2 0 0.0047 16 0 0 0 3.48E+06 1.91E+06 - - - 1.7889 0.9999 221125_WJC_METTL3_EV_vs_WT_F03.25312.25312.3 5.30E-07 19/56 R.RHPYFYAPELLFFAK.R "sp|P02768|ALBU_HUMAN,tr|B7WNR0|B7WNR0_HUMAN,tr|H7C013|H7C013_HUMAN,tr|H0YA55|H0YA55_HUMAN,tr|A0A0C4DGB6|A0A0C4DGB6_HUMAN,tr|D6RHD5|D6RHD5_HUMAN" 6 1897.9879 999 39584 25312 3 1897.994695 633.6699 Albumin OS=Homo sapiens OX=9606 GN=ALB PE=1 SV=2 8.5 3875.5 - 142215 - - - 3.5664 - 3.704 0.561 - 520.7 1 2 0 0.0068 15 0 0 0 7.31E+06 0.00E+00 - - - 8.2095 0.9993 221125_WJC_METTL3_EV_vs_WT_F03.25313.25313.3 0.0045 Aug-48 K.EFTNHWWNELFNK.T "sp|Q5T3I0|GPTC4_HUMAN,tr|E9PPY4|E9PPY4_HUMAN,tr|F2Z3C6|F2Z3C6_HUMAN,tr|F8W895|F8W895_HUMAN,tr|A0A0A0MRK1|A0A0A0MRK1_HUMAN,tr|E9PAV9|E9PAV9_HUMAN" 6 1763.8056 1.62 39585 25313 3 1763.808888 588.9425 G patch domain-containing protein 4 OS=Homo sapiens OX=9606 GN=GPATCH4 PE=1 SV=2 5.4 3875.6 - 134696 - - - 1.8613 - 1.543 0.383 - 101.7 1 2 0 0.0033 13 0 0 0 1.43E+06 8.81E+05 - - - 3.9851 1 221125_WJC_METTL3_EV_vs_WT_F03.25314.25314.3 7.44E-08 25/96 K.AGIEAGNINITSGEVFEIEEHISER[166.11].Q sp|O43172|PRP4_HUMAN 1 2723.3278 3.34 39586 25314 3 2723.348247 908.7832 U4\U6 small nuclear ribonucleoprotein Prp4 OS=Homo sapiens OX=9606 GN=PRPF4 PE=1 SV=2 4.2 3875.7 - 124909 - - - 7.5176 - 4.795 0.592 - 777 1 2 0 0.0205 25 0 0 0 3.27E+07 9.77E+06 - - - 8.741 1 221125_WJC_METTL3_EV_vs_WT_F03.25320.25320.3 2.61E-10 23/68 K.KIEDLGAAMEEALILDNK.Y "sp|Q13813|SPTN1_HUMAN,tr|A0A0D9SF54|A0A0D9SF54_HUMAN,tr|A0A0D9SGF6|A0A0D9SGF6_HUMAN" 3 1972.0187 2.86 39590 25320 3 1972.022282 658.3468 "Spectrin alpha chain, non-erythrocytic 1 OS=Homo sapiens OX=9606 GN=SPTAN1 PE=1 SV=3" 4.18 3876.5 - 1.40E+06 - - - 1.8195 - 4.083 0.629 - 893.5 1 2 0 0.0036 18 0 0 0 1.08E+07 3.76E+06 - - - 9.0549 0.9999 221125_WJC_METTL3_EV_vs_WT_F03.25323.25323.3 2.10E-07 18/68 K.QAAPPIELDAVWEDIR[166.11]ER[166.11].F "sp|O75400|PR40A_HUMAN,tr|A0A7N4I394|A0A7N4I394_HUMAN" 2 2127.0864 1.37 39593 25323 3 2127.086795 710.0361 Pre-mRNA-processing factor 40 homolog A OS=Homo sapiens OX=9606 GN=PRPF40A PE=1 SV=2 4.18 3876.9 - 842805 - - - 0.2054 - 3.29 0.496 - 442.8 1 2 1 0.0004 18 0 0 0 4.02E+06 2.93E+06 - - - 7.0352 0.9951 221125_WJC_METTL3_EV_vs_WT_F03.25324.25324.3 0.000292 13/72 R.VISEFVIPSVYWVEDQNK[136.11]K[136.11].N "sp|Q9H000|MKRN2_HUMAN,tr|A0A7I2V5D2|A0A7I2V5D2_HUMAN,tr|A0A7I2YQI0|A0A7I2YQI0_HUMAN,tr|C9J494|C9J494_HUMAN" 4 2295.2122 1.05 39594 25324 3 2295.224317 766.078 Probable E3 ubiquitin-protein ligase makorin-2 OS=Homo sapiens OX=9606 GN=MKRN2 PE=1 SV=2 4.68 3877 - 740400 - - - 5.2858 - 1.911 0.383 - 104 1 2 0 0.0121 19 0 0 0 1.02E+07 9.64E+06 - - - 4.3978 1 221125_WJC_METTL3_EV_vs_WT_F03.25326.25326.3 1.07E-20 32/124 R.MR[166.11]PGAYSTGYGGYEEYSGLSDGYGFTTDLFGR[166.11].D sp|P52597|HNRPF_HUMAN 1 3493.5312 -1 39596 25326 3 3493.523723 1165.5177 Heterogeneous nuclear ribonucleoprotein F OS=Homo sapiens OX=9606 GN=HNRNPF PE=1 SV=3 4.32 3877.3 - 634397 - - - -2.1377 - 5.42 0.826 - 978.5 1 2 0 -0.0075 32 0 0 0 0.00E+00 0.00E+00 - - - 11.6353 0.9976 221125_WJC_METTL3_EV_vs_WT_F03.25327.25327.4 0.00844 9/114 K.FLEVIKPFC[160.03]VILPEIQKPER.K "sp|P61619|S61A1_HUMAN,tr|B4DR61|B4DR61_HUMAN" 2 2454.3709 -1 39597 25327 4 2454.375493 614.6 Protein transport protein Sec61 subunit alpha isoform 1 OS=Homo sapiens OX=9606 GN=SEC61A1 PE=1 SV=2 6.22 3877.4 - 470161 - - - 1.8815 - 1.977 0.276 - 23.8 1 2 0 0.0046 20 0 0 0 0.00E+00 0.00E+00 - - - 1.8549 0.9998 221125_WJC_METTL3_EV_vs_WT_F03.25328.25328.3 1.13E-07 Dec-80 K.QNLHTWNSSLLDLETLSLQSR.A "sp|Q2NL68|PRSR3_HUMAN,tr|C9JFW7|C9JFW7_HUMAN" 2 2454.2503 -1 39598 25328 3 2454.259681 819.0907 Proline and serine-rich protein 3 OS=Homo sapiens OX=9606 GN=PROSER3 PE=1 SV=1 5.32 3877.6 - 464175 - - - 3.8215 - 2.521 0.51 - 89.8 1 2 0 0.0094 21 0 0 0 0.00E+00 0.00E+00 - - - 6.4402 0.9999 221125_WJC_METTL3_EV_vs_WT_F03.25331.25331.3 1.29E-05 Oct-72 R.AAALPAKPPNLDAALALLR.K sp|Q96GI7|FA89A_HUMAN 1 1885.1149 2.5 39601 25331 3 1885.116879 629.3789 Protein FAM89A OS=Homo sapiens OX=9606 GN=FAM89A PE=1 SV=1 8.79 3878 - 445612 - - - 1.0403 - 2.097 0.476 - 75.6 1 2 0 0.002 19 0 0 0 2.14E+06 8.56E+05 - - - 5.6657 1 221125_WJC_METTL3_EV_vs_WT_F03.25332.25332.2 8.92E-11 14/48 K.AGIEAGNINITSGEVFEIEEHISER.Q sp|O43172|PRP4_HUMAN 1 2713.3195 -1 39602 25332 2 2713.319086 1357.667 U4\U6 small nuclear ribonucleoprotein Prp4 OS=Homo sapiens OX=9606 GN=PRPF4 PE=1 SV=2 4.2 3878.1 - 444705 - - - -0.1541 - 3.518 0.724 - 337.5 1 2 0 -0.0004 25 0 0 0 0.00E+00 0.00E+00 - - - 7.4809 0.987 221125_WJC_METTL3_EV_vs_WT_F03.25333.25333.3 2.65E-05 18/64 N.QSLLTPLNLQIDPSIQR.V "sp|P13647|K2C5_HUMAN,tr|F8W0C6|F8W0C6_HUMAN,tr|F8VU69|F8VU69_HUMAN" 3 1935.0789 999 39603 25333 3 1935.08341 646.0336 "Keratin, type II cytoskeletal 5 OS=Homo sapiens OX=9606 GN=KRT5 PE=1 SV=3" 5.84 3878.2 - 416104 - - - 2.3172 - 3.182 0.394 - 284.3 1 1 0 0.0045 17 0 0 0 3.54E+06 0.00E+00 - - - 5.8557 0.9999 221125_WJC_METTL3_EV_vs_WT_F03.25334.25334.3 0.00109 12/120 R.TDPVPEEGEDVAATISATETLSEEEQEELRR.E "sp|P55327|TPD52_HUMAN,tr|H0YC44|H0YC44_HUMAN,tr|E5RFR7|E5RFR7_HUMAN,tr|H0YC42|H0YC42_HUMAN" 4 3429.5907 -1 39604 25334 3 3429.587293 1144.2042 Tumor protein D52 OS=Homo sapiens OX=9606 GN=TPD52 PE=1 SV=2 3.8 3878.4 - 403257 - - - -0.9969 - 1.956 0.448 - 61.7 1 2 0 -0.0034 31 0 0 0 0.00E+00 0.00E+00 - - - 5.0773 1 221125_WJC_METTL3_EV_vs_WT_F03.25339.25339.4 1.72E-10 17/84 R.RHPYFYAPELLFFAK.R "sp|P02768|ALBU_HUMAN,tr|B7WNR0|B7WNR0_HUMAN,tr|H7C013|H7C013_HUMAN,tr|H0YA55|H0YA55_HUMAN,tr|A0A0C4DGB6|A0A0C4DGB6_HUMAN,tr|D6RHD5|D6RHD5_HUMAN" 6 1897.9879 999 39608 25339 4 1897.987986 475.5043 Albumin OS=Homo sapiens OX=9606 GN=ALB PE=1 SV=2 8.5 3879 - 493965 - - - 0.0316 - 3.168 0.618 - 347.6 1 2 0 0.0001 15 0 0 0 2.05E+06 0.00E+00 - - - 5.0176 1 221125_WJC_METTL3_EV_vs_WT_F03.25349.25349.2 1.80E-13 21/44 R.GPGLGSTQGQTIALPAQGLIEFR[166.11].D sp|Q00577|PURA_HUMAN 1 2320.2415 1.79 39618 25349 2 2320.240256 1161.128 Transcriptional activator protein Pur-alpha OS=Homo sapiens OX=9606 GN=PURA PE=1 SV=2 6 3879.6 - 1.80E+06 - - - -0.5211 - 4.239 0.723 - 644.1 1 2 0 -0.0012 23 0 0 0 5.71E+06 3.18E+06 - - - 7.9316 0.9922 221125_WJC_METTL3_EV_vs_WT_F03.25351.25351.2 4.78E-05 14/32 N.QSLLTPLNLQIDPSIQR.V "sp|P13647|K2C5_HUMAN,tr|F8W0C6|F8W0C6_HUMAN,tr|F8VU69|F8VU69_HUMAN" 3 1935.0789 999 39620 25351 2 1935.076793 968.5467 "Keratin, type II cytoskeletal 5 OS=Homo sapiens OX=9606 GN=KRT5 PE=1 SV=3" 5.84 3879.9 - 1.60E+06 - - - -1.1023 - 2.748 0.488 - 392.4 1 1 0 -0.0021 17 0 0 0 5.19E+06 0.00E+00 - - - 5.13 1 221125_WJC_METTL3_EV_vs_WT_F03.25352.25352.2 3.32E-08 15/46 K.EETVLATVQALQTASHLSQQADLR[166.11].S sp|P04844|RPN2_HUMAN 1 2618.3539 -1 39621 25352 2 2618.35464 1310.1842 Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit 2 OS=Homo sapiens OX=9606 GN=RPN2 PE=1 SV=3 4.65 3880 - 1.34E+06 - - - 0.2715 - 2.82 0.567 - 376.9 1 2 0 0.0007 24 0 0 0 0.00E+00 0.00E+00 - - - 5.7775 1 221125_WJC_METTL3_EV_vs_WT_F03.25361.25361.3 6.77E-13 27/100 K.SMEFAPSEGAGTQDAAKPLEVLLLEK.N "sp|Q13948|CASP_HUMAN,sp|P39880|CUX1_HUMAN,tr|A0A2R8Y852|A0A2R8Y852_HUMAN,tr|A0A2R8YDI1|A0A2R8YDI1_HUMAN" 4 2730.3786 1.6 39628 25361 3 2730.37943 911.1335 Protein CASP OS=Homo sapiens OX=9606 GN=CUX1 PE=1 SV=2 4.25 3881.1 - 5.23E+06 - - - 0.3047 - 4.719 0.72 - 554.1 1 2 0 0.0008 26 0 0 0 1.09E+07 6.84E+06 - - - 10.1367 0.9999 221125_WJC_METTL3_EV_vs_WT_F03.25362.25362.3 9.97E-08 18/80 K.LSAVLEDTENWLYEDGEDQPK[136.11].Q "sp|O95757|HS74L_HUMAN,tr|E9PDE8|E9PDE8_HUMAN" 2 2458.1267 0.21 39629 25362 3 2458.11821 820.3829 Heat shock 70 kDa protein 4L OS=Homo sapiens OX=9606 GN=HSPA4L PE=1 SV=3 3.66 3881.2 - 3.53E+06 - - - -3.4661 - 3.376 0.62 - 385.3 1 2 0 -0.0085 21 0 0 0 1.50E+06 7.12E+06 - - - 8.367 1 221125_WJC_METTL3_EV_vs_WT_F03.25363.25363.3 5.49E-09 27/88 R.GPGLGSTQGQTIALPAQGLIEFR.D sp|Q00577|PURA_HUMAN 1 2310.2332 3.31 39630 25363 3 2310.23686 771.085 Transcriptional activator protein Pur-alpha OS=Homo sapiens OX=9606 GN=PURA PE=1 SV=2 6 3881.3 - 3.41E+06 - - - 1.5864 - 4.704 0.58 - 571.2 1 2 0 0.0037 23 0 0 0 1.10E+07 3.32E+06 - - - 8.6379 1 221125_WJC_METTL3_EV_vs_WT_F03.25365.25365.3 4.34E-11 27/92 K.GTAFVTLLNGEQAEAAINAFHQSR.L "sp|Q8IY67|RAVR1_HUMAN,tr|E9PAU2|E9PAU2_HUMAN,tr|A0A087WZ13|A0A087WZ13_HUMAN" 3 2544.2721 0.87 39632 25365 3 2544.270903 849.098 Ribonucleoprotein PTB-binding 1 OS=Homo sapiens OX=9606 GN=RAVER1 PE=1 SV=1 5.4 3881.6 - 1.31E+06 - - - -0.4705 - 4.783 0.632 - 896.2 1 2 0 -0.0012 24 0 0 0 4.15E+07 4.75E+07 - - - 9.2209 0.873 221125_WJC_METTL3_EV_vs_WT_F03.25366.25366.3 0.484 Oct-80 R.EVSQVDTIC[160.03]EC[160.03]LLEHEEQVLR[166.11].D sp|Q8WUM0|NU133_HUMAN 1 2595.2184 -1 39633 25366 3 2595.216913 866.0801 Nuclear pore complex protein Nup133 OS=Homo sapiens OX=9606 GN=NUP133 PE=1 SV=2 4.14 3881.7 - 1.14E+06 - - - -0.5818 - 1.278 0.125 - 44.2 3 2 0 -0.0015 21 0 0 0 0.00E+00 0.00E+00 - - - 0.3005 1 221125_WJC_METTL3_EV_vs_WT_F03.25368.25368.2 1.63E-08 17/40 K.LSAVLEDTENWLYEDGEDQPK[136.11].Q "sp|O95757|HS74L_HUMAN,tr|E9PDE8|E9PDE8_HUMAN" 2 2458.1267 -1 39635 25368 2 2458.122368 1230.0706 Heat shock 70 kDa protein 4L OS=Homo sapiens OX=9606 GN=HSPA4L PE=1 SV=3 3.66 3882 - 1.09E+06 - - - -1.7745 - 3.52 0.638 - 673.3 1 2 0 -0.0044 21 0 0 0 0.00E+00 0.00E+00 - - - 6.8459 1 221125_WJC_METTL3_EV_vs_WT_F03.25369.25369.3 2.90E-10 22/108 R.GHAVPPTLVPLMNGSATPLPTALGLGGR.A sp|Q7Z5L9|I2BP2_HUMAN 1 2693.4687 -1 39636 25369 3 2693.482033 898.8302 Interferon regulatory factor 2-binding protein 2 OS=Homo sapiens OX=9606 GN=IRF2BP2 PE=1 SV=2 9.76 3882.1 - 1.05E+06 - - - 4.9535 - 3.936 0.681 - 334.1 1 2 0 0.0133 28 0 0 0 0.00E+00 0.00E+00 - - - 9.281 0.9999 221125_WJC_METTL3_EV_vs_WT_F03.25375.25375.2 0.0004 Oct-34 K.EQMIDLQNLLTTQSPSVK.S sp|Q9BVJ6|UT14A_HUMAN 1 2044.0511 -1 39642 25375 2 2044.050353 1023.0328 U3 small nucleolar RNA-associated protein 14 homolog A OS=Homo sapiens OX=9606 GN=UTP14A PE=1 SV=1 4.37 3882.9 - 709500 - - - -0.3439 - 2.562 0.531 - 209.5 1 2 0 -0.0007 18 0 0 0 0.00E+00 0.00E+00 - - - 5.2757 0.997 221125_WJC_METTL3_EV_vs_WT_F03.25380.25380.3 0.045 Aug-60 K.ALFEEVPELLTEAEKK.E "sp|P31939|PUR9_HUMAN,tr|H7C1S2|H7C1S2_HUMAN" 2 1844.9771 0.2 39646 25380 3 1844.978258 615.9997 Bifunctional purine biosynthesis protein ATIC OS=Homo sapiens OX=9606 GN=ATIC PE=1 SV=3 4.33 3883.5 - 200577 - - - 0.6027 - 1.593 0.253 - 57.3 1 2 0 0.0011 16 0 0 0 1.14E+06 5.64E+06 - - - 2.5551 1 221125_WJC_METTL3_EV_vs_WT_F03.25381.25381.3 1.08E-11 23/88 R.IITITGTQDQIQNAQYLLQNSVK.Q sp|P61978|HNRPK_HUMAN 1 2588.381 1.84 39647 25381 3 2588.383986 863.8009 Heterogeneous nuclear ribonucleoprotein K OS=Homo sapiens OX=9606 GN=HNRNPK PE=1 SV=1 5.83 3883.6 - 4.61E+06 - - - 1.1606 - 3.785 0.62 - 594.6 1 2 0 0.003 23 0 0 0 1.71E+08 9.30E+07 - - - 8.5741 1 221125_WJC_METTL3_EV_vs_WT_F03.25382.25382.2 5.50E-12 16/24 R.SQDDAMVDYFFQR.Q "sp|Q14671|PUM1_HUMAN,tr|Q5T1Z8|Q5T1Z8_HUMAN,tr|E9PM68|E9PM68_HUMAN,tr|E9PMX1|E9PMX1_HUMAN,tr|H0YEH2|H0YEH2_HUMAN,tr|Q5T1Z4|Q5T1Z4_HUMAN,tr|E9PL65|E9PL65_HUMAN,tr|E9PR38|E9PR38_HUMAN" 8 1620.6879 2.28 39648 25382 2 1620.688045 811.3512 Pumilio homolog 1 OS=Homo sapiens OX=9606 GN=PUM1 PE=1 SV=3 3.93 3883.7 - 4.11E+06 - - - 0.116 - 3.423 0.742 - 1336.7 1 2 0 0.0002 13 0 0 0 6.62E+07 2.91E+07 - - - 7.6795 1 221125_WJC_METTL3_EV_vs_WT_F03.25383.25383.3 4.80E-10 19/88 R.IITITGTQDQIQNAQYLLQNSVK[136.11].Q sp|P61978|HNRPK_HUMAN 1 2596.3952 1.85 39649 25383 3 2596.39666 866.4723 Heterogeneous nuclear ribonucleoprotein K OS=Homo sapiens OX=9606 GN=HNRNPK PE=1 SV=1 5.83 3883.7 - 4.05E+06 - - - 0.5693 - 3.299 0.614 - 364.3 1 2 0 0.0015 23 0 0 0 1.72E+08 9.30E+07 - - - 8.1852 1 221125_WJC_METTL3_EV_vs_WT_F03.25386.25386.3 1.37E-08 14/48 R.SQDDAMVDYFFQR.Q "sp|Q14671|PUM1_HUMAN,tr|Q5T1Z8|Q5T1Z8_HUMAN,tr|E9PM68|E9PM68_HUMAN,tr|E9PMX1|E9PMX1_HUMAN,tr|H0YEH2|H0YEH2_HUMAN,tr|Q5T1Z4|Q5T1Z4_HUMAN,tr|E9PL65|E9PL65_HUMAN,tr|E9PR38|E9PR38_HUMAN" 8 1620.6879 2.46 39652 25386 3 1620.689199 541.2366 Pumilio homolog 1 OS=Homo sapiens OX=9606 GN=PUM1 PE=1 SV=3 3.93 3884 - 1.31E+06 - - - 0.828 - 2.54 0.646 - 332.9 1 2 0 0.0013 13 0 0 0 1.46E+07 5.94E+06 - - - 8.2693 1 221125_WJC_METTL3_EV_vs_WT_F03.25387.25387.2 2.03E-06 14/34 K.NKDGVLVDEFGLPQIPAS.- sp|Q9NZZ3|CHMP5_HUMAN 1 1897.9785 1.72 39653 25387 2 1897.979933 949.9965 Charged multivesicular body protein 5 OS=Homo sapiens OX=9606 GN=CHMP5 PE=1 SV=1 4.03 3884.1 - 1.17E+06 - - - 0.7324 - 2.712 0.589 - 309.5 1 2 1 0.0014 18 0 0 0 1.06E+07 6.17E+06 - - - 5.8438 1 221125_WJC_METTL3_EV_vs_WT_F03.25391.25391.3 1.25E-09 16/48 R.SQDDAMVDYFFQR[166.11].Q "sp|Q14671|PUM1_HUMAN,tr|Q5T1Z8|Q5T1Z8_HUMAN,tr|E9PM68|E9PM68_HUMAN,tr|E9PMX1|E9PMX1_HUMAN,tr|H0YEH2|H0YEH2_HUMAN,tr|Q5T1Z4|Q5T1Z4_HUMAN,tr|E9PL65|E9PL65_HUMAN,tr|E9PR38|E9PR38_HUMAN" 8 1630.6961 2.44 39657 25391 3 1630.698174 544.5727 Pumilio homolog 1 OS=Homo sapiens OX=9606 GN=PUM1 PE=1 SV=3 3.93 3884.6 - 623580 - - - 1.2553 - 2.687 0.636 - 419.5 1 2 0 0.002 13 0 0 0 1.45E+07 5.94E+06 - - - 8.3101 0.9999 221125_WJC_METTL3_EV_vs_WT_F03.25392.25392.3 6.95E-11 20/52 K.FC[160.03]FDLFQEIGKDDR.H sp|Q96P63|SPB12_HUMAN 1 1788.8141 9.92 39658 25392 3 1788.816462 597.2787 Serpin B12 OS=Homo sapiens OX=9606 GN=SERPINB12 PE=1 SV=1 4.23 3884.8 - 599808 - - - 1.3087 - 3.471 0.462 - 648.2 1 2 1 0.0023 14 0 0 0 3.80E+06 3.82E+05 - - - 6.9973 1 221125_WJC_METTL3_EV_vs_WT_F03.25395.25395.2 2.86E-16 25/44 R.IITITGTQDQIQNAQYLLQNSVK.Q sp|P61978|HNRPK_HUMAN 1 2588.381 1.28 39661 25395 2 2588.382743 1295.1978 Heterogeneous nuclear ribonucleoprotein K OS=Homo sapiens OX=9606 GN=HNRNPK PE=1 SV=1 5.83 3885.2 - 401027 - - - 0.6803 - 4.378 0.738 - 1883.5 1 2 0 0.0018 23 0 0 0 1.99E+07 1.56E+07 - - - 8.1216 1 221125_WJC_METTL3_EV_vs_WT_F03.25398.25398.2 6.53E-09 14/36 K.STNGDTFLGGEDFDQALLR[166.11].H "sp|P38646|GRP75_HUMAN,tr|H0Y8K0|H0Y8K0_HUMAN,tr|A0A7I2V2S7|A0A7I2V2S7_HUMAN,tr|A0A7I2V2G2|A0A7I2V2G2_HUMAN,tr|A0A7I2V3F7|A0A7I2V3F7_HUMAN,tr|A0A7I2YQB2|A0A7I2YQB2_HUMAN,tr|D6RCD7|D6RCD7_HUMAN" 7 2064.9628 -1 39664 25398 2 2065.947186 1033.4887 "Stress-70 protein, mitochondrial OS=Homo sapiens OX=9606 GN=HSPA9 PE=1 SV=2" 3.84 3885.6 - 353136 - - - 476.7171 - 3.133 0.604 - 420.2 1 2 0 0.9844 19 0 0 0 0.00E+00 0.00E+00 - - - 6.0007 1 221125_WJC_METTL3_EV_vs_WT_F03.25402.25402.2 8.99E-09 13/24 R.SQDDAMVDYFFQR[166.11].Q "sp|Q14671|PUM1_HUMAN,tr|Q5T1Z8|Q5T1Z8_HUMAN,tr|E9PM68|E9PM68_HUMAN,tr|E9PMX1|E9PMX1_HUMAN,tr|H0YEH2|H0YEH2_HUMAN,tr|Q5T1Z4|Q5T1Z4_HUMAN,tr|E9PL65|E9PL65_HUMAN,tr|E9PR38|E9PR38_HUMAN" 8 1630.6961 2.28 39667 25402 2 1630.694457 816.3553 Pumilio homolog 1 OS=Homo sapiens OX=9606 GN=PUM1 PE=1 SV=3 3.93 3886.1 - 5.31E+06 - - - -1.0241 - 3.169 0.692 - 683.3 1 2 0 -0.0017 13 0 0 0 6.62E+07 2.91E+07 - - - 7.1119 1 221125_WJC_METTL3_EV_vs_WT_F03.25403.25403.4 7.83E-09 21/156 R.GFGFVTFSSMAEVDAAMAARPHSIDGR.V "sp|P22626|ROA2_HUMAN,tr|A0A7I2YQN4|A0A7I2YQN4_HUMAN,tr|A0A7I2V4N0|A0A7I2V4N0_HUMAN,tr|A0A024RA28|A0A024RA28_HUMAN,tr|A0A7I2V4N1|A0A7I2V4N1_HUMAN,tr|A0A7I2V4I6|A0A7I2V4I6_HUMAN,tr|A0A087WUI2|A0A087WUI2_HUMAN,tr|A0A7I2V4S4|A0A7I2V4S4_HUMAN,tr|A0A7I2V323|A0A7I2V323_HUMAN,tr|A0A7I2V3P1|A0A7I2V3P1_HUMAN,tr|A0A7I2V3P7|A0A7I2V3P7_HUMAN" 11 2826.3218 0.63 39668 25403 4 2826.322046 707.5877 Heterogeneous nuclear ribonucleoproteins A2\B1 OS=Homo sapiens OX=9606 GN=HNRNPA2B1 PE=1 SV=2 5.38 3886.1 - 2.14E+06 - - - 0.098 - 3.629 0.569 - 301.7 1 2 0 0.0003 27 0 0 0 1.11E+07 1.76E+07 - - - 4.5818 0.9999 221125_WJC_METTL3_EV_vs_WT_F03.25404.25404.4 0.000176 23/156 R.GFGFVTFSSMAEVDAAMAAR[166.11]PHSIDGR[166.11].V "sp|P22626|ROA2_HUMAN,tr|A0A7I2YQN4|A0A7I2YQN4_HUMAN,tr|A0A7I2V4N0|A0A7I2V4N0_HUMAN,tr|A0A024RA28|A0A024RA28_HUMAN,tr|A0A7I2V4N1|A0A7I2V4N1_HUMAN,tr|A0A7I2V4I6|A0A7I2V4I6_HUMAN,tr|A0A087WUI2|A0A087WUI2_HUMAN,tr|A0A7I2V4S4|A0A7I2V4S4_HUMAN,tr|A0A7I2V323|A0A7I2V323_HUMAN,tr|A0A7I2V3P1|A0A7I2V3P1_HUMAN,tr|A0A7I2V3P7|A0A7I2V3P7_HUMAN" 11 2846.3383 0.7 39669 25404 4 2846.333511 712.5919 Heterogeneous nuclear ribonucleoproteins A2\B1 OS=Homo sapiens OX=9606 GN=HNRNPA2B1 PE=1 SV=2 5.38 3886.2 - 2.11E+06 - - - -1.6857 - 3.136 0.455 - 236.9 1 2 0 -0.0048 27 0 0 0 1.09E+07 1.57E+07 - - - 3.5426 1 221125_WJC_METTL3_EV_vs_WT_F03.25405.25405.3 2.46E-09 16/56 R.KIPNPDFFEDLEPFR.M "sp|P27824|CALX_HUMAN,tr|A0A7P0T937|A0A7P0T937_HUMAN,tr|A0A7P0T840|A0A7P0T840_HUMAN,tr|A0A7P0TB65|A0A7P0TB65_HUMAN,tr|A0A7P0TAE9|A0A7P0TAE9_HUMAN,tr|D6RGY2|D6RGY2_HUMAN,tr|A0A7P0T8G1|A0A7P0T8G1_HUMAN,tr|A0A7P0Z4D6|A0A7P0Z4D6_HUMAN,tr|A0A7P0T9L0|A0A7P0T9L0_HUMAN" 9 1862.9203 1.74 39670 25405 3 1862.918178 621.9807 Calnexin OS=Homo sapiens OX=9606 GN=CANX PE=1 SV=2 4.32 3886.3 - 850181 - - - -1.1391 - 3.052 0.578 - 306.7 1 2 0 -0.0021 15 0 0 0 7.99E+07 4.59E+07 - - - 7.8951 1 221125_WJC_METTL3_EV_vs_WT_F03.25406.25406.3 0.00118 17/120 K.AFLADPSAFVAAAPVAAATTAAPAAAAAPAK[136.11].V "sp|P05388|RLA0_HUMAN,tr|F8VWS0|F8VWS0_HUMAN,tr|F8W1K8|F8W1K8_HUMAN" 3 2759.4738 1.38 39671 25406 3 2759.474924 920.8319 60S acidic ribosomal protein P0 OS=Homo sapiens OX=9606 GN=RPLP0 PE=1 SV=1 5.88 3886.5 - 794509 - - - 0.4196 - 3.343 0.504 - 225.4 1 2 0 0.0012 31 0 0 0 1.47E+08 1.07E+08 - - - 6.9353 0.9935 221125_WJC_METTL3_EV_vs_WT_F03.25407.25407.2 5.30E-08 14/32 R.DSEYIFSAEFITADSSK[136.11].E "sp|O43148|MCES_HUMAN,tr|K7EP06|K7EP06_HUMAN" 2 1916.8771 1.14 39672 25407 2 1917.882369 959.4458 mRNA cap guanine-N7 methyltransferase OS=Homo sapiens OX=9606 GN=RNMT PE=1 SV=1 3.92 3886.6 - 392295 - - - 524.428 - 2.166 0.575 - 570.1 1 2 0 1.0053 17 0 0 0 2.96E+06 2.59E+06 - - - 4.8725 0.9967 221125_WJC_METTL3_EV_vs_WT_F03.25408.25408.3 0.00376 Nov-68 K.NK[136.11]DGVLVDEFGLPQIPAS.- sp|Q9NZZ3|CHMP5_HUMAN 1 1905.9927 5.32 39673 25408 3 1905.991777 636.3382 Charged multivesicular body protein 5 OS=Homo sapiens OX=9606 GN=CHMP5 PE=1 SV=1 4.03 3886.7 - 270194 - - - -0.5068 - 1.898 0.306 - 71.2 1 2 1 -0.001 18 0 0 0 9.13E+06 1.71E+06 - - - 3.547 1 221125_WJC_METTL3_EV_vs_WT_F03.25414.25414.2 1.70E-14 26/44 R.IITITGTQDQIQNAQYLLQNSVK[136.11].Q sp|P61978|HNRPK_HUMAN 1 2596.3952 1.28 39677 25414 2 2596.389712 1299.2049 Heterogeneous nuclear ribonucleoprotein K OS=Homo sapiens OX=9606 GN=HNRNPK PE=1 SV=1 5.83 3887.4 - 9.37E+06 - - - -2.1068 - 4.603 0.721 - 1975.2 1 2 0 -0.0055 23 0 0 0 1.99E+07 1.56E+07 - - - 8.1181 0.9879 221125_WJC_METTL3_EV_vs_WT_F03.25415.25415.3 0.000146 14/48 K.K[136.11]VSQEILELLNTT.T "sp|Q86U44|MTA70_HUMAN,tr|H0YFV6|H0YFV6_HUMAN" 2 1494.8385 0.01 39678 25415 3 1494.836099 499.2868 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 4.53 3887.6 - 1.93E+06 - - - -1.5888 - 2.401 0.398 - 372.9 1 1 0 -0.0024 13 0 0 0 3.44E+04 4.35E+06 - - - 5.3514 0.9999 221125_WJC_METTL3_EV_vs_WT_F03.25419.25419.4 1.74E-05 11/132 R.IITITGTQDQIQNAQYLLQNSVK.Q sp|P61978|HNRPK_HUMAN 1 2588.381 1.54 39682 25419 4 2588.382167 648.1025 Heterogeneous nuclear ribonucleoprotein K OS=Homo sapiens OX=9606 GN=HNRNPK PE=1 SV=1 5.83 3888.1 - 1.98E+06 - - - 0.4578 - 2.399 0.411 - 83.2 1 2 0 0.0012 23 0 0 0 2.57E+06 1.67E+06 - - - 3.0865 1 221125_WJC_METTL3_EV_vs_WT_F03.25420.25420.4 4.77E-07 11/132 R.IITITGTQDQIQNAQYLLQNSVK[136.11].Q sp|P61978|HNRPK_HUMAN 1 2596.3952 -1 39683 25420 4 2596.397112 650.1061 Heterogeneous nuclear ribonucleoprotein K OS=Homo sapiens OX=9606 GN=HNRNPK PE=1 SV=1 5.83 3888.2 - 1.68E+06 - - - 0.7433 - 2.525 0.523 - 63.6 1 2 0 0.0019 23 0 0 0 0.00E+00 0.00E+00 - - - 4.0777 1 221125_WJC_METTL3_EV_vs_WT_F03.25423.25423.4 6.75E-13 19/108 R.ADLEMQIESLKEELAYLKK.N sp|P02533|K1C14_HUMAN 1 2250.1817 999 39686 25423 4 2250.177164 563.5527 "Keratin, type I cytoskeletal 14 OS=Homo sapiens OX=9606 GN=KRT14 PE=1 SV=4" 4.59 3888.6 - 1.27E+06 - - - -2.0318 - 4.21 0.622 - 364.3 1 2 1 -0.0046 19 0 0 0 9.72E+07 0.00E+00 - - - 5.1249 1 221125_WJC_METTL3_EV_vs_WT_F03.25426.25426.2 1.83E-08 17/36 R.GIDVQQVSLVINYDLPTNR.E "sp|Q14240|IF4A2_HUMAN,sp|P60842|IF4A1_HUMAN,tr|E7EQG2|E7EQG2_HUMAN" 3 2143.1273 -1 39689 25426 2 2143.121381 1072.5709 Eukaryotic initiation factor 4A-II OS=Homo sapiens OX=9606 GN=EIF4A2 PE=1 SV=2 4.21 3889 - 1.00E+06 - - - -2.7772 - 3.367 0.584 - 831.7 1 2 0 -0.006 19 0 0 0 0.00E+00 0.00E+00 - - - 6.3373 0.9945 221125_WJC_METTL3_EV_vs_WT_F03.25427.25427.2 9.65E-07 14/34 K.NK[136.11]DGVLVDEFGLPQIPAS.- sp|Q9NZZ3|CHMP5_HUMAN 1 1905.9927 1.9 39690 25427 2 1905.986678 954.0036 Charged multivesicular body protein 5 OS=Homo sapiens OX=9606 GN=CHMP5 PE=1 SV=1 4.03 3889.1 - 887677 - - - -3.1821 - 2.439 0.55 - 267.3 1 2 1 -0.0061 18 0 0 0 1.17E+07 6.17E+06 - - - 5.2934 1 221125_WJC_METTL3_EV_vs_WT_F03.25432.25432.2 8.84E-15 17/46 K.GTAFVTLLNGEQAEAAINAFHQSR[166.11].L "sp|Q8IY67|RAVR1_HUMAN,tr|E9PAU2|E9PAU2_HUMAN,tr|A0A087WZ13|A0A087WZ13_HUMAN" 3 2554.2804 -1 39695 25432 2 2554.269255 1278.1475 Ribonucleoprotein PTB-binding 1 OS=Homo sapiens OX=9606 GN=RAVER1 PE=1 SV=1 5.4 3889.8 - 455764 - - - -4.3515 - 4.024 0.662 - 684.9 1 2 0 -0.0111 24 0 0 0 0.00E+00 0.00E+00 - - - 7.35 0.9999 221125_WJC_METTL3_EV_vs_WT_F03.25435.25435.3 0.000109 Oct-56 K.VSQEILELLNTTTAK[136.11].E "sp|Q86U44|MTA70_HUMAN,tr|H0YFV6|H0YFV6_HUMAN" 2 1666.9233 0.001 39697 25435 3 1666.920637 556.6484 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 4.53 3890.1 - 25455.4 - - - -1.5778 - 2.287 0.455 - 170.7 1 2 0 -0.0026 15 0 0 0 0.00E+00 6.30E+05 - - - 5.7706 1 221125_WJC_METTL3_EV_vs_WT_F03.25439.25439.3 1.08E-08 18/56 R.K[136.11]IPNPDFFEDLEPFR[166.11].M "sp|P27824|CALX_HUMAN,tr|A0A7P0T937|A0A7P0T937_HUMAN,tr|A0A7P0T840|A0A7P0T840_HUMAN,tr|A0A7P0TB65|A0A7P0TB65_HUMAN,tr|A0A7P0TAE9|A0A7P0TAE9_HUMAN,tr|D6RGY2|D6RGY2_HUMAN,tr|A0A7P0T8G1|A0A7P0T8G1_HUMAN,tr|A0A7P0Z4D6|A0A7P0Z4D6_HUMAN,tr|A0A7P0T9L0|A0A7P0T9L0_HUMAN" 9 1880.9428 1.68 39700 25439 3 1880.945002 627.9882 Calnexin OS=Homo sapiens OX=9606 GN=CANX PE=1 SV=2 4.32 3890.7 - 421491 - - - 1.1866 - 3.293 0.593 - 433.2 1 2 0 0.0022 15 0 0 0 6.30E+07 3.74E+07 - - - 8.2606 0.9999 221125_WJC_METTL3_EV_vs_WT_F03.25442.25442.3 6.41E-05 13/80 R.VPAPVTMDSFFFGC[160.03]ELSGHTR.S sp|O75607|NPM3_HUMAN 1 2354.0824 0.62 39703 25442 3 2354.085787 785.7014 Nucleoplasmin-3 OS=Homo sapiens OX=9606 GN=NPM3 PE=1 SV=3 5.32 3891.1 - 224987 - - - 1.4498 - 1.977 0.49 - 130.4 1 2 0 0.0034 21 0 0 0 1.02E+06 1.63E+06 - - - 5.6361 0.9998 221125_WJC_METTL3_EV_vs_WT_F03.25443.25443.2 0.000167 20-Sep R.NPEAALSPTFR[166.11].S "sp|Q86U44|MTA70_HUMAN,tr|B4E349|B4E349_HUMAN,tr|F5H6D8|F5H6D8_HUMAN,tr|B4DTN4|B4DTN4_HUMAN" 4 1211.6174 0.001 39704 25443 2 1211.618095 606.816 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 6 3891.2 - 214399 - - - 0.5678 - 2.042 0.469 - 278 1 2 0 0.0007 11 0 0 0 0.00E+00 1.34E+06 - - - 4.4362 0.9971 221125_WJC_METTL3_EV_vs_WT_F03.25446.25446.2 0.0336 30-Apr K.GGDINFVFTGFSVNGK.V "sp|Q15155|NOMO1_HUMAN,sp|Q5JPE7|NOMO2_HUMAN,sp|P69849|NOMO3_HUMAN,tr|I3L0Q6|I3L0Q6_HUMAN,tr|A0A7I2V686|A0A7I2V686_HUMAN,tr|H3BTW1|H3BTW1_HUMAN,tr|A0A7I2V3P4|A0A7I2V3P4_HUMAN,tr|A0A7I2V6B0|A0A7I2V6B0_HUMAN,tr|A0A7I2V4D7|A0A7I2V4D7_HUMAN,tr|A0A7I2V4T6|A0A7I2V4T6_HUMAN,tr|A0A087X117|A0A087X117_HUMAN,tr|A0A7I2V2V8|A0A7I2V2V8_HUMAN,tr|A0A0G2JN29|A0A0G2JN29_HUMAN,tr|A0A7I2V2Z5|A0A7I2V2Z5_HUMAN,tr|J3KN36|J3KN36_HUMAN" 15 1657.81 0.83 39707 25446 2 1657.808589 829.9123 Nodal modulator 1 OS=Homo sapiens OX=9606 GN=NOMO1 PE=1 SV=5 5.84 3891.6 - 107408 - - - -0.8638 - 1.23 0.315 - 26.3 4 2 0 -0.0014 16 0 0 0 6.84E+05 8.28E+05 - - - 1.6072 1 221125_WJC_METTL3_EV_vs_WT_F03.25450.25450.3 9.15E-11 27/92 K.GTAFVTLLNGEQAEAAINAFHQSR[166.11].L "sp|Q8IY67|RAVR1_HUMAN,tr|E9PAU2|E9PAU2_HUMAN,tr|A0A087WZ13|A0A087WZ13_HUMAN" 3 2554.2804 0.87 39709 25450 3 2554.279416 852.4341 Ribonucleoprotein PTB-binding 1 OS=Homo sapiens OX=9606 GN=RAVER1 PE=1 SV=1 5.4 3892.1 - 1.25E+07 - - - -0.3735 - 4.851 0.652 - 939 1 2 0 -0.001 24 0 0 0 4.15E+07 4.75E+07 - - - 9.4767 1 221125_WJC_METTL3_EV_vs_WT_F03.25452.25452.3 2.30E-10 22/72 R.ADLEMQIESLKEELAYLKK.N sp|P02533|K1C14_HUMAN 1 2250.1817 999 39711 25452 3 2250.172098 751.0679 "Keratin, type I cytoskeletal 14 OS=Homo sapiens OX=9606 GN=KRT14 PE=1 SV=4" 4.59 3892.3 - 3.67E+07 - - - -4.2832 - 4.556 0.606 - 840.4 1 2 1 -0.0096 19 0 0 0 3.86E+07 0.00E+00 - - - 9.0192 1 221125_WJC_METTL3_EV_vs_WT_F03.25455.25455.4 1.09E-10 22/138 K.HAAWYPSEILDPHVVLLTSDNVIR.L "sp|Q99567|NUP88_HUMAN,tr|J3KMX1|J3KMX1_HUMAN,tr|I3L245|I3L245_HUMAN" 3 2744.4286 1.89 39714 25455 4 2744.430761 687.1144 Nuclear pore complex protein Nup88 OS=Homo sapiens OX=9606 GN=NUP88 PE=1 SV=2 5.21 3892.7 - 1.91E+06 - - - 0.7874 - 3.745 0.605 - 239.4 1 2 0 0.0022 24 0 0 0 2.65E+06 1.40E+06 - - - 4.9151 1 221125_WJC_METTL3_EV_vs_WT_F03.25457.25457.2 1.85E-15 21/36 R.ADLEMQIESLKEELAYLKK.N sp|P02533|K1C14_HUMAN 1 2250.1817 -1 39716 25457 2 2250.173328 1126.0981 "Keratin, type I cytoskeletal 14 OS=Homo sapiens OX=9606 GN=KRT14 PE=1 SV=4" 4.59 3893 - 1.74E+06 - - - -3.7366 - 4.462 0.728 - 1284 1 2 1 -0.0084 19 0 0 0 0.00E+00 0.00E+00 - - - 8.0924 1 221125_WJC_METTL3_EV_vs_WT_F03.25458.25458.2 9.26E-11 17/38 K.GMSLNLEPDNVGVVVFGNDK.L "sp|P25705|ATPA_HUMAN,tr|K7EQH4|K7EQH4_HUMAN,tr|K7ERX7|K7ERX7_HUMAN,tr|K7EK77|K7EK77_HUMAN,tr|K7EJP1|K7EJP1_HUMAN" 5 2103.0307 6.47 39717 25458 2 2103.025087 1052.5226 "ATP synthase subunit alpha, mitochondrial OS=Homo sapiens OX=9606 GN=ATP5F1A PE=1 SV=1" 4.03 3893.1 - 1.28E+06 - - - -2.6476 - 3.036 0.673 - 653.5 1 2 0 -0.0056 20 0 0 0 2.72E+06 4.20E+05 - - - 6.7403 0.9999 221125_WJC_METTL3_EV_vs_WT_F03.25459.25459.3 0.000132 17/76 K.GMSLNLEPDNVGVVVFGNDK.L "sp|P25705|ATPA_HUMAN,tr|K7EQH4|K7EQH4_HUMAN,tr|K7ERX7|K7ERX7_HUMAN,tr|K7EK77|K7EK77_HUMAN,tr|K7EJP1|K7EJP1_HUMAN" 5 2103.0307 1.71 39718 25459 3 2103.026361 702.0175 "ATP synthase subunit alpha, mitochondrial OS=Homo sapiens OX=9606 GN=ATP5F1A PE=1 SV=1" 4.03 3893.2 - 719764 - - - -2.0418 - 2.9 0.46 - 361.5 1 2 0 -0.0043 20 0 0 0 2.93E+06 1.71E+06 - - - 6.2504 1 221125_WJC_METTL3_EV_vs_WT_F03.25460.25460.4 9.29E-07 25/138 K.GTAFVTLLNGEQAEAAINAFHQSR.L "sp|Q8IY67|RAVR1_HUMAN,tr|E9PAU2|E9PAU2_HUMAN,tr|A0A087WZ13|A0A087WZ13_HUMAN" 3 2544.2721 0.66 39719 25460 4 2544.273331 637.0753 Ribonucleoprotein PTB-binding 1 OS=Homo sapiens OX=9606 GN=RAVER1 PE=1 SV=1 5.4 3893.4 - 674145 - - - 0.4838 - 4.318 0.513 - 532.5 1 2 0 0.0012 24 0 0 0 1.08E+06 1.65E+06 - - - 4.1603 0.9991 221125_WJC_METTL3_EV_vs_WT_F03.25461.25461.2 2.74E-06 14/32 R.DLNC[160.03]VPEIADTLGAVAK.Q "sp|O14744|ANM5_HUMAN,tr|C9JSX3|C9JSX3_HUMAN,tr|G3V580|G3V580_HUMAN,tr|G3V2L6|G3V2L6_HUMAN,tr|G3V2F5|G3V2F5_HUMAN,tr|G3V2X6|G3V2X6_HUMAN,tr|G3V507|G3V507_HUMAN" 7 1784.8979 3.18 39720 25461 2 1784.89065 893.4562 Protein arginine N-methyltransferase 5 OS=Homo sapiens OX=9606 GN=PRMT5 PE=1 SV=4 4.03 3893.5 - 633836 - - - -4.0338 - 2.604 0.548 - 419 1 2 0 -0.0072 17 0 0 0 8.99E+07 2.82E+07 - - - 5.4392 1 221125_WJC_METTL3_EV_vs_WT_F03.25462.25462.4 8.04E-07 24/138 K.GTAFVTLLNGEQAEAAINAFHQSR[166.11].L "sp|Q8IY67|RAVR1_HUMAN,tr|E9PAU2|E9PAU2_HUMAN,tr|A0A087WZ13|A0A087WZ13_HUMAN" 3 2554.2804 0.66 39721 25462 4 2554.280087 639.5774 Ribonucleoprotein PTB-binding 1 OS=Homo sapiens OX=9606 GN=RAVER1 PE=1 SV=1 5.4 3893.6 - 614343 - - - -0.1108 - 4.27 0.502 - 448.4 1 2 0 -0.0003 24 0 0 0 1.08E+06 1.65E+06 - - - 4.0612 0.9984 221125_WJC_METTL3_EV_vs_WT_F03.25464.25464.3 1.54E-09 20/112 K.MK[136.11]ETAENYLGHTAK[136.11]NAVITVPAYFNDSQR[166.11].Q "sp|P38646|GRP75_HUMAN,tr|H0Y8K0|H0Y8K0_HUMAN,tr|A0A7I2V2S7|A0A7I2V2S7_HUMAN,tr|A0A7I2V2G2|A0A7I2V2G2_HUMAN,tr|A0A7I2V3F7|A0A7I2V3F7_HUMAN,tr|A0A7I2YQB2|A0A7I2YQB2_HUMAN,tr|D6RCD7|D6RCD7_HUMAN" 7 3293.6349 0.001 39723 25464 3 3293.621629 1098.8856 "Stress-70 protein, mitochondrial OS=Homo sapiens OX=9606 GN=HSPA9 PE=1 SV=2" 6.51 3893.9 - 528129 - - - -4.0387 - 3.284 0.432 - 165 1 2 2 -0.0133 29 0 0 0 0.00E+00 2.62E+06 - - - 6.0883 1 221125_WJC_METTL3_EV_vs_WT_F03.25465.25465.2 4.80E-08 16/46 K.GTAFVTLLNGEQAEAAINAFHQSR.L "sp|Q8IY67|RAVR1_HUMAN,tr|E9PAU2|E9PAU2_HUMAN,tr|A0A087WZ13|A0A087WZ13_HUMAN" 3 2544.2721 -1 39724 25465 2 2544.263525 1273.1433 Ribonucleoprotein PTB-binding 1 OS=Homo sapiens OX=9606 GN=RAVER1 PE=1 SV=1 5.4 3894 - 525059 - - - -3.3703 - 4.112 0.669 - 485.1 1 2 0 -0.0086 24 0 0 0 0.00E+00 0.00E+00 - - - 7.4557 1 221125_WJC_METTL3_EV_vs_WT_F03.25473.25473.3 7.23E-13 25/84 K.EK[136.11]PYFPIPEEYTFIQNVPLEDR[166.11].V "sp|Q00839|HNRPU_HUMAN,tr|A0A1W2PQL0|A0A1W2PQL0_HUMAN,tr|A0A1W2PPL4|A0A1W2PPL4_HUMAN,tr|A0A1W2PQ74|A0A1W2PQ74_HUMAN,tr|Q5RI18|Q5RI18_HUMAN,tr|A0A1W2PP35|A0A1W2PP35_HUMAN,tr|A0A1W2PPS1|A0A1W2PPS1_HUMAN,tr|A0A1W2PRZ7|A0A1W2PRZ7_HUMAN,tr|A0A1W2PPH7|A0A1W2PPH7_HUMAN,tr|A0A1W2PP34|A0A1W2PP34_HUMAN,tr|A0A1X7SBS1|A0A1X7SBS1_HUMAN" 11 2741.3708 1.25 39731 25473 3 2741.364822 914.7975 Heterogeneous nuclear ribonucleoprotein U OS=Homo sapiens OX=9606 GN=HNRNPU PE=1 SV=6 4.25 3894.9 - 5.23E+07 - - - -2.1639 - 4.392 0.664 - 482.9 1 2 0 -0.0059 22 0 0 0 1.35E+09 1.08E+09 - - - 9.4496 1 221125_WJC_METTL3_EV_vs_WT_F03.25474.25474.3 1.87E-09 22/76 R.QFGFIVLTTSAGIMDHEEAR.R sp|P62244|RS15A_HUMAN 1 2221.0838 0.92 39732 25474 3 2221.084776 741.3685 40S ribosomal protein S15a OS=Homo sapiens OX=9606 GN=RPS15A PE=1 SV=2 4.65 3895 - 1.23E+06 - - - 0.4601 - 4.053 0.674 - 699.7 1 2 0 0.001 20 0 0 0 7.09E+06 7.72E+06 - - - 9.4493 0.9998 221125_WJC_METTL3_EV_vs_WT_F03.25475.25475.3 3.16E-06 14/76 R.QFGFIVLTTSAGIMDHEEAR[166.11].R sp|P62244|RS15A_HUMAN 1 2231.092 0.93 39733 25475 3 2231.085238 744.7046 40S ribosomal protein S15a OS=Homo sapiens OX=9606 GN=RPS15A PE=1 SV=2 4.65 3895.1 - 1.11E+06 - - - -3.0416 - 2.804 0.431 - 231.7 1 2 0 -0.0068 20 0 0 0 7.09E+06 7.65E+06 - - - 5.8447 0.9999 221125_WJC_METTL3_EV_vs_WT_F03.25478.25478.3 1.44E-06 Nov-60 K.K[136.11]VSQEILELLNTTTAK[136.11].E "sp|Q86U44|MTA70_HUMAN,tr|H0YFV6|H0YFV6_HUMAN" 2 1803.0324 -1 39736 25478 3 1803.026983 602.0181 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 6.14 3895.4 - 0 - - - -3.021 - 2.342 0.532 - 135.5 1 2 0 -0.0054 16 0 0 0 0.00E+00 0.00E+00 - - - 6.6533 1 221125_WJC_METTL3_EV_vs_WT_F03.25482.25482.4 2.95E-10 20/126 K.EKPYFPIPEEYTFIQNVPLEDR.V "sp|Q00839|HNRPU_HUMAN,tr|A0A1W2PQL0|A0A1W2PQL0_HUMAN,tr|A0A1W2PPL4|A0A1W2PPL4_HUMAN,tr|A0A1W2PQ74|A0A1W2PQ74_HUMAN,tr|Q5RI18|Q5RI18_HUMAN,tr|A0A1W2PP35|A0A1W2PP35_HUMAN,tr|A0A1W2PPS1|A0A1W2PPS1_HUMAN,tr|A0A1W2PRZ7|A0A1W2PRZ7_HUMAN,tr|A0A1W2PPH7|A0A1W2PPH7_HUMAN,tr|A0A1W2PP34|A0A1W2PP34_HUMAN,tr|A0A1X7SBS1|A0A1X7SBS1_HUMAN" 11 2723.3483 1.11 39738 25482 4 2723.345731 681.8443 Heterogeneous nuclear ribonucleoprotein U OS=Homo sapiens OX=9606 GN=HNRNPU PE=1 SV=6 4.25 3895.8 - 3.42E+06 - - - -0.9374 - 4.279 0.669 - 157.7 1 2 0 -0.0026 22 0 0 0 3.11E+07 2.81E+07 - - - 5.5239 0.9854 221125_WJC_METTL3_EV_vs_WT_F03.25486.25486.2 1.38E-08 14/26 K.K[136.11]VSQEILELLNTTT.A "sp|Q86U44|MTA70_HUMAN,tr|H0YFV6|H0YFV6_HUMAN" 2 1595.8862 0 39742 25486 2 1595.882386 798.9504 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 4.53 3896.2 - 1.55E+06 - - - -2.3604 - 2.71 0.538 - 785 1 1 0 -0.0038 14 0 0 0 1.65E+06 4.43E+08 - - - 5.5153 0.9999 221125_WJC_METTL3_EV_vs_WT_F03.25487.25487.3 4.71E-11 24/68 R.FLSQPFQVAEVFTGHMGK.L sp|P06576|ATPB_HUMAN 1 2022.0033 1.81 39743 25487 3 2021.994836 675.0084 "ATP synthase subunit beta, mitochondrial OS=Homo sapiens OX=9606 GN=ATP5F1B PE=1 SV=3" 6.75 3896.3 - 1.15E+06 - - - -4.1948 - 3.833 0.532 - 552.9 1 2 0 -0.0085 18 0 0 0 2.96E+07 1.64E+07 - - - 7.8147 0.8626 221125_WJC_METTL3_EV_vs_WT_F03.25490.25490.3 0.191 Sep-68 R.QTLSTPGTIILGTIPVPK.G "sp|Q9BSD7|NTPCR_HUMAN,tr|Q5TDF0|Q5TDF0_HUMAN" 2 1835.0768 1.29 39746 25490 3 1835.069698 612.6995 Cancer-related nucleoside-triphosphatase OS=Homo sapiens OX=9606 GN=NTPCR PE=1 SV=1 8.75 3896.7 - 494877 - - - -3.8707 - 1.409 0.187 - 36 2 2 0 -0.0071 18 0 0 0 4.25E+07 3.30E+07 - - - 1.3374 0.9999 221125_WJC_METTL3_EV_vs_WT_F03.25491.25491.3 1.15E-06 14/64 R.DLNC[160.03]VPEIADTLGAVAK.Q "sp|O14744|ANM5_HUMAN,tr|C9JSX3|C9JSX3_HUMAN,tr|G3V580|G3V580_HUMAN,tr|G3V2L6|G3V2L6_HUMAN,tr|G3V2F5|G3V2F5_HUMAN,tr|G3V2X6|G3V2X6_HUMAN,tr|G3V507|G3V507_HUMAN" 7 1784.8979 3.52 39747 25491 3 1784.891454 595.9732 Protein arginine N-methyltransferase 5 OS=Homo sapiens OX=9606 GN=PRMT5 PE=1 SV=4 4.03 3896.8 - 443072 - - - -3.5834 - 2.612 0.543 - 234.7 1 2 0 -0.0064 17 0 0 0 3.73E+07 1.06E+07 - - - 7.0177 1 221125_WJC_METTL3_EV_vs_WT_F03.25494.25494.4 2.34E-07 21/96 R.TFHIFYQLLSGAGEHLK[136.11].S sp|P35580|MYH10_HUMAN 1 1968.0349 1.65 39750 25494 4 1968.034144 493.016 Myosin-10 OS=Homo sapiens OX=9606 GN=MYH10 PE=1 SV=3 6.61 3897.2 - 0 - - - -0.3755 - 3.221 0.556 - 366.3 1 2 0 -0.0007 17 0 0 0 4.28E+06 2.60E+06 - - - 4.4713 1 221125_WJC_METTL3_EV_vs_WT_F03.25497.25497.2 5.90E-12 21/42 K.EKPYFPIPEEYTFIQNVPLEDR.V "sp|Q00839|HNRPU_HUMAN,tr|A0A1W2PQL0|A0A1W2PQL0_HUMAN,tr|A0A1W2PPL4|A0A1W2PPL4_HUMAN,tr|A0A1W2PQ74|A0A1W2PQ74_HUMAN,tr|Q5RI18|Q5RI18_HUMAN,tr|A0A1W2PP35|A0A1W2PP35_HUMAN,tr|A0A1W2PPS1|A0A1W2PPS1_HUMAN,tr|A0A1W2PRZ7|A0A1W2PRZ7_HUMAN,tr|A0A1W2PPH7|A0A1W2PPH7_HUMAN,tr|A0A1W2PP34|A0A1W2PP34_HUMAN,tr|A0A1X7SBS1|A0A1X7SBS1_HUMAN" 11 2723.3483 4.09 39751 25497 2 2723.341327 1362.6814 Heterogeneous nuclear ribonucleoprotein U OS=Homo sapiens OX=9606 GN=HNRNPU PE=1 SV=6 4.25 3897.6 - 1.01E+07 - - - -2.5546 - 3.605 0.709 - 589.5 1 2 0 -0.007 22 0 0 0 3.70E+07 9.03E+06 - - - 7.4281 1 221125_WJC_METTL3_EV_vs_WT_F03.25498.25498.2 1.32E-15 20/42 K.EK[136.11]PYFPIPEEYTFIQNVPLEDR[166.11].V "sp|Q00839|HNRPU_HUMAN,tr|A0A1W2PQL0|A0A1W2PQL0_HUMAN,tr|A0A1W2PPL4|A0A1W2PPL4_HUMAN,tr|A0A1W2PQ74|A0A1W2PQ74_HUMAN,tr|Q5RI18|Q5RI18_HUMAN,tr|A0A1W2PP35|A0A1W2PP35_HUMAN,tr|A0A1W2PPS1|A0A1W2PPS1_HUMAN,tr|A0A1W2PRZ7|A0A1W2PRZ7_HUMAN,tr|A0A1W2PPH7|A0A1W2PPH7_HUMAN,tr|A0A1W2PP34|A0A1W2PP34_HUMAN,tr|A0A1X7SBS1|A0A1X7SBS1_HUMAN" 11 2741.3708 4.09 39752 25498 2 2741.363081 1371.6927 Heterogeneous nuclear ribonucleoprotein U OS=Homo sapiens OX=9606 GN=HNRNPU PE=1 SV=6 4.25 3897.7 - 8.76E+06 - - - -2.799 - 3.866 0.75 - 657.1 1 2 0 -0.0077 22 0 0 0 3.70E+07 9.03E+06 - - - 7.9026 1 221125_WJC_METTL3_EV_vs_WT_F03.25499.25499.3 1.14E-08 21/68 K.EAQTSFLHLGYLPNQLFR.T "sp|Q92499|DDX1_HUMAN,tr|A0A7I2V2M5|A0A7I2V2M5_HUMAN,tr|A0A087X2G1|A0A087X2G1_HUMAN,tr|A0A7I2V430|A0A7I2V430_HUMAN,tr|A0A7I2V4F0|A0A7I2V4F0_HUMAN,tr|A0A087WZ71|A0A087WZ71_HUMAN,tr|A0A7I2YQ77|A0A7I2YQ77_HUMAN" 7 2133.1007 1.25 39753 25499 3 2133.098584 712.0409 ATP-dependent RNA helicase DDX1 OS=Homo sapiens OX=9606 GN=DDX1 PE=1 SV=2 6.85 3897.7 - 2.83E+07 - - - -1.0032 - 3.741 0.561 - 448.1 1 2 0 -0.0021 18 0 0 0 6.77E+07 5.40E+07 - - - 8.0793 1 221125_WJC_METTL3_EV_vs_WT_F03.25500.25500.3 4.77E-08 15/68 K.EAQTSFLHLGYLPNQLFR[166.11].T "sp|Q92499|DDX1_HUMAN,tr|A0A7I2V2M5|A0A7I2V2M5_HUMAN,tr|A0A087X2G1|A0A087X2G1_HUMAN,tr|A0A7I2V430|A0A7I2V430_HUMAN,tr|A0A7I2V4F0|A0A7I2V4F0_HUMAN,tr|A0A087WZ71|A0A087WZ71_HUMAN,tr|A0A7I2YQ77|A0A7I2YQ77_HUMAN" 7 2143.109 1.25 39754 25500 3 2143.103839 715.3769 ATP-dependent RNA helicase DDX1 OS=Homo sapiens OX=9606 GN=DDX1 PE=1 SV=2 6.85 3897.8 - 2.40E+07 - - - -2.4054 - 3.068 0.535 - 201.5 1 2 0 -0.0052 18 0 0 0 6.77E+07 5.40E+07 - - - 7.2948 0.9817 221125_WJC_METTL3_EV_vs_WT_F03.25501.25501.3 1.57E-05 Nov-52 K.K[136.11]VSQEILELLNTTT.A "sp|Q86U44|MTA70_HUMAN,tr|H0YFV6|H0YFV6_HUMAN" 2 1595.8862 0.01 39755 25501 3 1595.88036 532.9693 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 4.53 3897.8 - 1.69E+07 - - - -3.63 - 2.38 0.509 - 199.5 1 1 0 -0.0058 14 0 0 0 1.52E+05 2.56E+07 - - - 6.5176 1 221125_WJC_METTL3_EV_vs_WT_F03.25502.25502.3 9.15E-11 20/80 R.IPLNPYLNLHSLLPASNLAGK[136.11].E "tr|E9PAU2|E9PAU2_HUMAN,tr|A0A087WZ13|A0A087WZ13_HUMAN" 2 2252.2772 1.04 39756 25502 3 2252.272759 751.7664 Ribonucleoprotein PTB-binding 1 OS=Homo sapiens OX=9606 GN=RAVER1 PE=1 SV=1 8.6 3897.9 - 1.26E+07 - - - -1.9891 - 3.959 0.654 - 411.8 1 2 0 -0.0045 21 0 0 0 1.94E+07 1.86E+07 - - - 9.1291 1 221125_WJC_METTL3_EV_vs_WT_F03.25503.25503.4 3.03E-08 17/126 K.EK[136.11]PYFPIPEEYTFIQNVPLEDR[166.11].V "sp|Q00839|HNRPU_HUMAN,tr|A0A1W2PQL0|A0A1W2PQL0_HUMAN,tr|A0A1W2PPL4|A0A1W2PPL4_HUMAN,tr|A0A1W2PQ74|A0A1W2PQ74_HUMAN,tr|Q5RI18|Q5RI18_HUMAN,tr|A0A1W2PP35|A0A1W2PP35_HUMAN,tr|A0A1W2PPS1|A0A1W2PPS1_HUMAN,tr|A0A1W2PRZ7|A0A1W2PRZ7_HUMAN,tr|A0A1W2PPH7|A0A1W2PPH7_HUMAN,tr|A0A1W2PP34|A0A1W2PP34_HUMAN,tr|A0A1X7SBS1|A0A1X7SBS1_HUMAN" 11 2741.3708 1.1 39757 25503 4 2741.364647 686.35 Heterogeneous nuclear ribonucleoprotein U OS=Homo sapiens OX=9606 GN=HNRNPU PE=1 SV=6 4.25 3897.9 - 8.72E+06 - - - -2.2277 - 3.492 0.549 - 120.6 1 2 0 -0.0061 22 0 0 0 3.10E+07 2.81E+07 - - - 4.412 1 221125_WJC_METTL3_EV_vs_WT_F03.25504.25504.2 2.97E-08 21/34 K.EAQTSFLHLGYLPNQLFR.T "sp|Q92499|DDX1_HUMAN,tr|A0A7I2V2M5|A0A7I2V2M5_HUMAN,tr|A0A087X2G1|A0A087X2G1_HUMAN,tr|A0A7I2V430|A0A7I2V430_HUMAN,tr|A0A7I2V4F0|A0A7I2V4F0_HUMAN,tr|A0A087WZ71|A0A087WZ71_HUMAN,tr|A0A7I2YQ77|A0A7I2YQ77_HUMAN" 7 2133.1007 -1 39758 25504 2 2133.096679 1067.5576 ATP-dependent RNA helicase DDX1 OS=Homo sapiens OX=9606 GN=DDX1 PE=1 SV=2 6.85 3898 - 8.56E+06 - - - -1.8963 - 3.878 0.662 - 1160.7 1 2 0 -0.004 18 0 0 0 0.00E+00 0.00E+00 - - - 7.2614 1 221125_WJC_METTL3_EV_vs_WT_F03.25505.25505.3 1.57E-14 28/100 R.LESLSAATTFEPLEPVKDTDIQGFLK.N "sp|Q8N1F7|NUP93_HUMAN,tr|H3BM93|H3BM93_HUMAN,tr|H3BV11|H3BV11_HUMAN,tr|H3BRI8|H3BRI8_HUMAN,tr|H3BNN5|H3BNN5_HUMAN,tr|H3BVG0|H3BVG0_HUMAN" 6 2848.4746 2.33 39759 25505 3 2848.467228 950.4988 Nuclear pore complex protein Nup93 OS=Homo sapiens OX=9606 GN=NUP93 PE=1 SV=2 4.18 3898.1 - 7.14E+06 - - - -2.5905 - 5.027 0.674 - 782.1 1 2 1 -0.0074 26 0 0 0 1.21E+07 5.19E+06 - - - 9.7675 1 221125_WJC_METTL3_EV_vs_WT_F03.25507.25507.3 7.32E-11 23/116 K.GAVDDDVAEADIISTVEFNHSGELLATGDK.G "sp|P63151|2ABA_HUMAN,tr|E5RIY1|E5RIY1_HUMAN" 2 3087.452 -1 39761 25507 3 3087.442972 1030.158 Serine\threonine-protein phosphatase 2A 55 kDa regulatory subunit B alpha isoform OS=Homo sapiens OX=9606 GN=PPP2R2A PE=1 SV=1 3.8 3898.3 - 3.79E+06 - - - -2.9351 - 5.357 0.662 - 611.3 1 2 0 -0.0091 30 0 0 0 0.00E+00 0.00E+00 - - - 9.7795 1 221125_WJC_METTL3_EV_vs_WT_F03.25508.25508.3 0.000102 16/56 K.EISLWFKPEELVDYK.S "sp|P22392|NDKB_HUMAN,tr|Q32Q12|Q32Q12_HUMAN" 2 1894.9717 2.11 39762 25508 3 1894.968259 632.6645 Nucleoside diphosphate kinase B OS=Homo sapiens OX=9606 GN=NME2 PE=1 SV=1 4.41 3898.4 - 3.65E+06 - - - -1.7984 - 2.875 0.469 - 267.7 1 2 0 -0.0034 15 0 0 0 6.19E+06 2.93E+06 - - - 6.5236 0.9874 221125_WJC_METTL3_EV_vs_WT_F03.25510.25510.3 4.17E-05 18/68 A.SLLTTAEVVVTEIPKEEK.D "sp|P10809|CH60_HUMAN,tr|A0A7I2V2X6|A0A7I2V2X6_HUMAN,tr|A0A7I2YQK6|A0A7I2YQK6_HUMAN" 3 1985.0932 1.28 39764 25510 3 1985.090627 662.705 "60 kDa heat shock protein, mitochondrial OS=Homo sapiens OX=9606 GN=HSPD1 PE=1 SV=2" 4.49 3898.7 - 2.92E+06 - - - -1.3158 - 2.753 0.522 - 237.4 1 1 1 -0.0026 18 0 0 0 1.93E+07 1.51E+07 - - - 6.8808 0.9732 221125_WJC_METTL3_EV_vs_WT_F03.25511.25511.3 0.000347 13/68 A.SLLTTAEVVVTEIPK[136.11]EEK[136.11].D "sp|P10809|CH60_HUMAN,tr|A0A7I2V2X6|A0A7I2V2X6_HUMAN,tr|A0A7I2YQK6|A0A7I2YQK6_HUMAN" 3 2001.1216 0.95 39765 25511 3 2001.119498 668.0478 "60 kDa heat shock protein, mitochondrial OS=Homo sapiens OX=9606 GN=HSPD1 PE=1 SV=2" 4.49 3898.8 - 2.81E+06 - - - -1.0699 - 2.774 0.423 - 132.6 1 1 1 -0.0021 18 0 0 0 4.86E+06 5.09E+06 - - - 5.7961 0.9999 221125_WJC_METTL3_EV_vs_WT_F03.25516.25516.3 0.00372 Oct-44 R.KGIVLLEELLPK.G sp|Q9Y3D6|FIS1_HUMAN 1 1350.8486 1.31 39770 25516 3 1350.845825 451.2902 Mitochondrial fission 1 protein OS=Homo sapiens OX=9606 GN=FIS1 PE=1 SV=2 6.14 3899.5 - 517495 - - - -2.0831 - 1.859 0.514 - 166.6 1 2 0 -0.0028 12 0 0 0 8.92E+05 6.81E+05 - - - 5.9885 1 221125_WJC_METTL3_EV_vs_WT_F03.25520.25520.3 7.51E-07 17/68 R.FLSQPFQVAEVFTGHMGK[136.11].L sp|P06576|ATPB_HUMAN 1 2030.0175 1.8 39772 25520 3 2030.018158 677.6798 "ATP synthase subunit beta, mitochondrial OS=Homo sapiens OX=9606 GN=ATP5F1B PE=1 SV=3" 6.75 3899.9 - 2.05E+06 - - - 0.3153 - 2.7 0.473 - 273.6 1 2 0 0.0006 18 0 0 0 2.98E+07 1.65E+07 - - - 6.2866 1 221125_WJC_METTL3_EV_vs_WT_F03.25523.25523.3 2.21E-12 20/80 K.ASYGVEDPEYAVTQLAQTTMR.S "sp|Q9UJZ1|STML2_HUMAN,tr|A0A087WYB4|A0A087WYB4_HUMAN" 2 2329.0896 2.49 39775 25523 3 2329.089313 777.3705 "Stomatin-like protein 2, mitochondrial OS=Homo sapiens OX=9606 GN=STOML2 PE=1 SV=1" 4.14 3900.3 - 1.45E+06 - - - -0.1348 - 3.699 0.609 - 335.8 1 2 0 -0.0003 21 0 0 0 2.13E+07 8.58E+06 - - - 8.4657 1 221125_WJC_METTL3_EV_vs_WT_F03.25524.25524.2 6.86E-10 21/34 R.QTLSTPGTIILGTIPVPK[136.11].G "sp|Q9BSD7|NTPCR_HUMAN,tr|Q5TDF0|Q5TDF0_HUMAN" 2 1843.091 1.19 39776 25524 2 1843.087841 922.5528 Cancer-related nucleoside-triphosphatase OS=Homo sapiens OX=9606 GN=NTPCR PE=1 SV=1 8.75 3900.4 - 1.25E+06 - - - -1.7145 - 3.57 0.684 - 1189.2 1 2 0 -0.0032 18 0 0 0 4.53E+07 3.81E+07 - - - 7.2207 1 221125_WJC_METTL3_EV_vs_WT_F03.25525.25525.3 5.03E-08 16/68 R.QTLSTPGTIILGTIPVPK[136.11].G "sp|Q9BSD7|NTPCR_HUMAN,tr|Q5TDF0|Q5TDF0_HUMAN" 2 1843.091 1.29 39777 25525 3 1843.089967 615.3709 Cancer-related nucleoside-triphosphatase OS=Homo sapiens OX=9606 GN=NTPCR PE=1 SV=1 8.75 3900.5 - 1.21E+06 - - - -0.561 - 2.535 0.602 - 257.1 1 2 0 -0.001 18 0 0 0 4.25E+07 3.30E+07 - - - 7.5677 1 221125_WJC_METTL3_EV_vs_WT_F03.25529.25529.3 3.69E-14 17/96 R.MAEAGFIHC[160.03]PTENEPDLAQC[160.03]FFC[160.03]FK.E "sp|O15392|BIRC5_HUMAN,tr|A0A0B4J1S3|A0A0B4J1S3_HUMAN,tr|K7ELG2|K7ELG2_HUMAN,tr|K7EP76|K7EP76_HUMAN,tr|K7EMW2|K7EMW2_HUMAN,tr|H3BLT4|H3BLT4_HUMAN" 6 3018.2809 3.52 39781 25529 3 3018.274864 1007.1009 Baculoviral IAP repeat-containing protein 5 OS=Homo sapiens OX=9606 GN=BIRC5 PE=1 SV=3 4.4 3901.1 - 551067 - - - -1.9972 - 3.577 0.76 - 230.3 1 2 0 -0.006 25 0 0 0 4.18E+06 1.19E+06 - - - 9.9438 1 221125_WJC_METTL3_EV_vs_WT_F03.25530.25530.2 2.17E-10 16/32 R.DLNC[160.03]VPEIADTLGAVAK[136.11].Q "sp|O14744|ANM5_HUMAN,tr|C9JSX3|C9JSX3_HUMAN,tr|G3V580|G3V580_HUMAN,tr|G3V2L6|G3V2L6_HUMAN,tr|G3V2F5|G3V2F5_HUMAN,tr|G3V2X6|G3V2X6_HUMAN,tr|G3V507|G3V507_HUMAN" 7 1792.912 3.25 39782 25530 2 1792.913429 897.4633 Protein arginine N-methyltransferase 5 OS=Homo sapiens OX=9606 GN=PRMT5 PE=1 SV=4 4.03 3901.2 - 463417 - - - 0.7691 - 2.701 0.622 - 590.9 1 2 0 0.0014 17 0 0 0 9.18E+07 2.82E+07 - - - 6.0775 1 221125_WJC_METTL3_EV_vs_WT_F03.25536.25536.3 1.17E-13 24/72 R.ITEDYYVHLIADNLPVATR.L "sp|Q92544|TM9S4_HUMAN,tr|A0A0C4DFM1|A0A0C4DFM1_HUMAN" 2 2202.1321 1.01 39786 25536 3 2202.134597 735.0513 Transmembrane 9 superfamily member 4 OS=Homo sapiens OX=9606 GN=TM9SF4 PE=1 SV=2 4.54 3902 - 449119 - - - 1.1412 - 4.02 0.713 - 613.4 1 2 0 0.0025 19 0 0 0 5.05E+07 4.98E+07 - - - 9.9067 0.9999 221125_WJC_METTL3_EV_vs_WT_F03.25539.25539.3 4.49E-08 Nov-64 R.DLNC[160.03]VPEIADTLGAVAK[136.11].Q "sp|O14744|ANM5_HUMAN,tr|C9JSX3|C9JSX3_HUMAN,tr|G3V580|G3V580_HUMAN,tr|G3V2L6|G3V2L6_HUMAN,tr|G3V2F5|G3V2F5_HUMAN,tr|G3V2X6|G3V2X6_HUMAN,tr|G3V507|G3V507_HUMAN" 7 1792.912 3.51 39789 25539 3 1792.907071 598.6446 Protein arginine N-methyltransferase 5 OS=Homo sapiens OX=9606 GN=PRMT5 PE=1 SV=4 4.03 3902.3 - 306629 - - - -2.777 - 2.517 0.544 - 195.2 1 2 0 -0.005 17 0 0 0 3.70E+07 1.05E+07 - - - 6.9356 1 221125_WJC_METTL3_EV_vs_WT_F03.25540.25540.3 9.21E-06 Nov-48 K.SYHLSELVQQILK[136.11].T "sp|P09884|DPOLA_HUMAN,tr|A6NMQ1|A6NMQ1_HUMAN" 2 1564.8704 0.59 39790 25540 3 1564.87187 522.6308 DNA polymerase alpha catalytic subunit OS=Homo sapiens OX=9606 GN=POLA1 PE=1 SV=2 6.47 3902.4 - 360204 - - - 0.9119 - 2.115 0.603 - 89.2 1 2 0 0.0014 13 0 0 0 1.26E+06 2.15E+06 - - - 7.2934 1 221125_WJC_METTL3_EV_vs_WT_F03.25542.25542.2 1.68E-09 16/36 R.ITEDYYVHLIADNLPVATR.L "sp|Q92544|TM9S4_HUMAN,tr|A0A0C4DFM1|A0A0C4DFM1_HUMAN" 2 2202.1321 1.04 39792 25542 2 2202.134873 1102.0733 Transmembrane 9 superfamily member 4 OS=Homo sapiens OX=9606 GN=TM9SF4 PE=1 SV=2 4.54 3902.7 - 0 - - - 1.2665 - 3.245 0.676 - 667.3 1 2 0 0.0028 19 0 0 0 8.16E+06 7.88E+06 - - - 6.9271 0.9384 221125_WJC_METTL3_EV_vs_WT_F03.25543.25543.2 4.82 Jul-36 R.DTLVQGLNEAGDDLEAVAK.F "sp|Q9Y6E2|BZW2_HUMAN,tr|F8WDX8|F8WDX8_HUMAN,tr|E7EMS9|E7EMS9_HUMAN,tr|E9PFE3|E9PFE3_HUMAN,tr|E7ETZ4|E7ETZ4_HUMAN,tr|C9JF98|C9JF98_HUMAN,tr|Q75MG1|Q75MG1_HUMAN" 7 1956.964 1.73 39793 25543 2 1956.963421 979.4893 Basic leucine zipper and W2 domain-containing protein 2 OS=Homo sapiens OX=9606 GN=BZW2 PE=1 SV=1 3.77 3902.8 - 131566 - - - -0.304 - 0.979 0.088 - 17.4 3 2 0 -0.0006 19 0 0 0 5.58E+06 3.23E+06 - - - -0.5745 1 221125_WJC_METTL3_EV_vs_WT_F03.25549.25549.2 2.62E-09 20/34 R.QTLSTPGTIILGTIPVPK.G "sp|Q9BSD7|NTPCR_HUMAN,tr|Q5TDF0|Q5TDF0_HUMAN" 2 1835.0768 1.19 39797 25549 2 1835.07702 918.5457 Cancer-related nucleoside-triphosphatase OS=Homo sapiens OX=9606 GN=NTPCR PE=1 SV=1 8.75 3903.5 - 2.02E+06 - - - 0.1193 - 3.64 0.705 - 1048.5 1 2 0 0.0002 18 0 0 0 4.53E+07 3.81E+07 - - - 7.4245 1 221125_WJC_METTL3_EV_vs_WT_F03.25550.25550.3 1.28E-14 27/92 K.ETVYC[160.03]LNDDDETEVLKEDIIQGFR.Y sp|P13010|XRCC5_HUMAN 1 2900.3386 1.23 39798 25550 3 2900.341791 967.7868 X-ray repair cross-complementing protein 5 OS=Homo sapiens OX=9606 GN=XRCC5 PE=1 SV=3 3.85 3903.6 - 390214 - - - 1.1057 - 5.062 0.77 - 918.4 1 2 1 0.0032 24 0 0 0 1.44E+07 1.17E+07 - - - 10.8906 1 221125_WJC_METTL3_EV_vs_WT_F03.25551.25551.3 8.01E-13 27/76 R.TPLTQDPASITDNLLQLPAR.R sp|Q96DF8|ESS2_HUMAN 1 2163.1535 1.86 39799 25551 3 2163.157256 722.0585 Splicing factor ESS-2 homolog OS=Homo sapiens OX=9606 GN=ESS2 PE=1 SV=1 4.21 3903.8 - 591407 - - - 1.7142 - 4.375 0.664 - 941.4 1 2 0 0.0037 20 0 0 0 3.71E+07 1.99E+07 - - - 9.5225 1 221125_WJC_METTL3_EV_vs_WT_F03.25554.25554.3 4.57E-18 30/92 K.ETVYC[160.03]LNDDDETEVLK[136.11]EDIIQGFR[166.11].Y sp|P13010|XRCC5_HUMAN 1 2918.3611 1.23 39802 25554 3 2918.358395 973.7943 X-ray repair cross-complementing protein 5 OS=Homo sapiens OX=9606 GN=XRCC5 PE=1 SV=3 3.85 3904.2 - 398630 - - - -0.9111 - 5.463 0.774 - 1337.1 1 2 1 -0.0027 24 0 0 0 1.44E+07 1.17E+07 - - - 11.1124 1 221125_WJC_METTL3_EV_vs_WT_F03.25559.25559.3 8.22E-06 Sep-96 R.MAEAGFIHC[160.03]PTENEPDLAQC[160.03]FFC[160.03]FK[136.11].E "sp|O15392|BIRC5_HUMAN,tr|A0A0B4J1S3|A0A0B4J1S3_HUMAN,tr|K7ELG2|K7ELG2_HUMAN,tr|K7EP76|K7EP76_HUMAN,tr|K7EMW2|K7EMW2_HUMAN,tr|H3BLT4|H3BLT4_HUMAN" 6 3026.2951 3.52 39807 25559 3 3026.294681 1009.7723 Baculoviral IAP repeat-containing protein 5 OS=Homo sapiens OX=9606 GN=BIRC5 PE=1 SV=3 4.4 3904.8 - 153806 - - - -0.1358 - 2.122 0.653 - 54.4 1 2 0 -0.0004 25 0 0 0 4.18E+06 1.19E+06 - - - 7.5511 0.819 221125_WJC_METTL3_EV_vs_WT_F03.25562.25562.2 0.00796 Oct-36 K.LLHHLSDLALTLPTDAVSI.C "sp|Q86U44|MTA70_HUMAN,tr|B4E349|B4E349_HUMAN,tr|F5H6D8|F5H6D8_HUMAN,tr|H0YFV6|H0YFV6_HUMAN,tr|B4DTN4|B4DTN4_HUMAN" 5 2028.1255 - 39810 25562 2 2028.124992 1015.07 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 5.05 3905.2 - 139837 - - - -0.2712 - 1.694 0.134 - 173.6 1 1 0 -0.0006 19 0 0 0 - - - - - 1.3264 1 221125_WJC_METTL3_EV_vs_WT_F03.25566.25566.3 5.45E-11 23/76 R.TPLTQDPASITDNLLQLPAR[166.11].R sp|Q96DF8|ESS2_HUMAN 1 2173.1618 1.83 39812 25566 3 2173.164275 725.3945 Splicing factor ESS-2 homolog OS=Homo sapiens OX=9606 GN=ESS2 PE=1 SV=1 4.21 3905.8 - 1.80E+06 - - - 1.1306 - 3.608 0.626 - 652.1 1 2 0 0.0025 20 0 0 0 3.71E+07 2.02E+07 - - - 8.6316 0.9999 221125_WJC_METTL3_EV_vs_WT_F03.25567.25567.3 2.54E-06 13/68 R.EEEEFNTGPLSVLTQSVK.N "sp|P62316|SMD2_HUMAN,tr|K7ERG4|K7ERG4_HUMAN" 2 2005.9844 1.72 39813 25567 3 2005.988711 669.6687 Small nuclear ribonucleoprotein Sm D2 OS=Homo sapiens OX=9606 GN=SNRPD2 PE=1 SV=1 4.09 3905.9 - 1.09E+06 - - - 2.1406 - 2.529 0.479 - 203.2 1 2 0 0.0043 18 0 0 0 2.77E+07 1.61E+07 - - - 6.1896 0.9799 221125_WJC_METTL3_EV_vs_WT_F03.25568.25568.3 5.49E-05 15/88 R.NAGGEEAALALAEGLHC[160.03]GSALFR.H sp|Q9BU89|DOHH_HUMAN 1 2313.1172 2.61 39814 25568 3 2314.110622 772.0463 Deoxyhypusine hydroxylase OS=Homo sapiens OX=9606 GN=DOHH PE=1 SV=1 4.75 3906.1 - 3.50E+06 - - - 429.4823 - 2.468 0.458 - 162.4 1 2 0 0.9934 23 0 0 0 9.15E+06 3.50E+06 - - - 5.4904 1 221125_WJC_METTL3_EV_vs_WT_F03.25569.25569.2 0.000111 22/36 R.YVASYLLAALGGNSSPSAK.D sp|P05387|RLA2_HUMAN 1 1867.968 1.52 39815 25569 2 1867.967602 934.9913 60S acidic ribosomal protein P2 OS=Homo sapiens OX=9606 GN=RPLP2 PE=1 SV=1 8.5 3906.2 - 1.20E+06 - - - -0.2018 - 3.704 0.633 - 1493.1 1 2 0 -0.0004 19 0 0 0 5.14E+08 3.38E+08 - - - 6.9355 1 221125_WJC_METTL3_EV_vs_WT_F03.25570.25570.4 5.74E-08 28/252 K.LLAAYPGASGLGSAAAAAAAAASC[160.03]HLHLPPPAAPGSPGSLSLR.N sp|Q9H7S9|ZN703_HUMAN 1 3947.0476 1.63 39816 25570 4 3947.045333 987.7692 Zinc finger protein 703 OS=Homo sapiens OX=9606 GN=ZNF703 PE=1 SV=1 8.24 3906.3 - 1.05E+06 - - - -0.5718 - 3.934 0.561 - 227.2 1 2 0 -0.0023 43 0 0 0 9.57E+06 5.89E+06 - - - 4.4981 1 221125_WJC_METTL3_EV_vs_WT_F03.25571.25571.4 2.01E-10 21/120 N.VGTRPINLEPIFQGYIDSLKR.Y sp|P35908|K22E_HUMAN 1 2415.3274 999 39817 25571 4 2415.331865 604.8391 "Keratin, type II cytoskeletal 2 epidermal OS=Homo sapiens OX=9606 GN=KRT2 PE=1 SV=2" 8.56 3906.4 - 975446 - - - 1.8362 - 4.06 0.621 - 329.7 1 1 0 0.0044 21 0 0 0 6.09E+06 0.00E+00 - - - 5.0932 1 221125_WJC_METTL3_EV_vs_WT_F03.25572.25572.2 5.45E-14 24/38 R.TPLTQDPASITDNLLQLPAR.R sp|Q96DF8|ESS2_HUMAN 1 2163.1535 2.36 39818 25572 2 2163.1525 1082.5841 Splicing factor ESS-2 homolog OS=Homo sapiens OX=9606 GN=ESS2 PE=1 SV=1 4.21 3906.6 - 963193 - - - -0.4845 - 4.381 0.734 - 1509.2 1 2 0 -0.001 20 0 0 0 2.22E+07 9.39E+06 - - - 8.0939 0.9999 221125_WJC_METTL3_EV_vs_WT_F03.25573.25573.3 9.65E-09 Dec-88 R.TDITYPAGFMDVISIDKTGENFR.L sp|P62701|RS4X_HUMAN 1 2589.2421 1.08 39819 25573 3 2589.243263 864.088 "40S ribosomal protein S4, X isoform OS=Homo sapiens OX=9606 GN=RPS4X PE=1 SV=2" 4.23 3906.7 - 546440 - - - 0.4472 - 2.873 0.614 - 111.9 1 2 1 0.0012 23 0 0 0 4.57E+06 4.23E+06 - - - 7.861 1 221125_WJC_METTL3_EV_vs_WT_F03.25574.25574.2 6.05E-08 13/34 R.EEEEFNTGPLSVLTQSVK.N "sp|P62316|SMD2_HUMAN,tr|K7ERG4|K7ERG4_HUMAN" 2 2005.9844 1.8 39820 25574 2 2005.981837 1003.9995 Small nuclear ribonucleoprotein Sm D2 OS=Homo sapiens OX=9606 GN=SNRPD2 PE=1 SV=1 4.09 3906.8 - 530025 - - - -1.2862 - 3.042 0.635 - 480.4 1 2 0 -0.0026 18 0 0 0 9.69E+06 5.40E+06 - - - 6.4655 0.9998 221125_WJC_METTL3_EV_vs_WT_F03.25575.25575.3 0.00184 Nov-60 R.QNLEPLFEQYINNLRR.Q "sp|P48668|K2C6C_HUMAN,sp|P04259|K2C6B_HUMAN,sp|P13647|K2C5_HUMAN,sp|P02538|K2C6A_HUMAN,tr|F8W0C6|F8W0C6_HUMAN" 5 2046.0647 999 39821 25575 3 2046.065643 683.0288 "Keratin, type II cytoskeletal 6C OS=Homo sapiens OX=9606 GN=KRT6C PE=1 SV=3" 6.14 3907 - 485311 - - - 0.4741 - 2.138 0.383 - 125.2 1 2 0 0.001 16 0 0 0 3.63E+06 0.00E+00 - - - 4.7595 0.9618 221125_WJC_METTL3_EV_vs_WT_F03.25578.25578.4 0.807 10/102 K.EEGFPIR[166.11]PHYFWPLLVGR[166.11].R "sp|P42704|LPPRC_HUMAN,tr|A0A804HI14|A0A804HI14_HUMAN,tr|A0A804HL40|A0A804HL40_HUMAN,tr|A0A804HKJ0|A0A804HKJ0_HUMAN,tr|A0A804HKR3|A0A804HKR3_HUMAN,tr|A0A0C4DG06|A0A0C4DG06_HUMAN,tr|A0A804HIN4|A0A804HIN4_HUMAN,tr|A0A804HLG8|A0A804HLG8_HUMAN,tr|A0A804HIV5|A0A804HIV5_HUMAN,tr|A0A804HHY9|A0A804HHY9_HUMAN,tr|A0A804HJH8|A0A804HJH8_HUMAN,tr|B8ZZ38|B8ZZ38_HUMAN,tr|A0A804HI40|A0A804HI40_HUMAN,tr|A0A804HJZ1|A0A804HJZ1_HUMAN,tr|C9JCA9|C9JCA9_HUMAN,tr|A0A804HIQ7|A0A804HIQ7_HUMAN,tr|A0A804HK30|A0A804HK30_HUMAN,tr|A0A804HKI2|A0A804HKI2_HUMAN,tr|A0A804HKR5|A0A804HKR5_HUMAN,tr|A0A804HKX0|A0A804HKX0_HUMAN,tr|A0A804HIG4|A0A804HIG4_HUMAN,tr|A0A804HK02|A0A804HK02_HUMAN" 22 2232.1747 1.43 39824 25578 4 2232.173149 559.051 "Leucine-rich PPR motif-containing protein, mitochondrial OS=Homo sapiens OX=9606 GN=LRPPRC PE=1 SV=3" 6.86 3907.4 - 409083 - - - -0.7033 - 1.816 0.147 - 84.3 1 2 0 -0.0016 18 0 0 0 2.77E+06 1.94E+06 - - - 0.7094 0.9999 221125_WJC_METTL3_EV_vs_WT_F03.25580.25580.3 9.16E-06 Oct-56 K.GVETIANDVVSLATK.A "sp|P10515|ODP2_HUMAN,tr|A0A7P0TBE2|A0A7P0TBE2_HUMAN,tr|A0A7P0Z4G4|A0A7P0Z4G4_HUMAN,tr|A0A7P0TAX2|A0A7P0TAX2_HUMAN,tr|A0A7P0TBK2|A0A7P0TBK2_HUMAN,tr|E9PEJ4|E9PEJ4_HUMAN,tr|A0A7P0TAG1|A0A7P0TAG1_HUMAN,tr|A0A7P0TA47|A0A7P0TA47_HUMAN,tr|A0A7P0T997|A0A7P0T997_HUMAN,tr|H0YDD4|H0YDD4_HUMAN" 10 1515.8144 0.99 39826 25580 3 1515.817546 506.2788 "Dihydrolipoyllysine-residue acetyltransferase component of pyruvate dehydrogenase complex, mitochondrial OS=Homo sapiens OX=9606 GN=DLAT PE=1 SV=3" 4.37 3907.6 - 367417 - - - 2.0504 - 1.987 0.482 - 100.6 1 2 0 0.0031 15 0 0 0 2.31E+06 2.34E+06 - - - 5.7046 0.9999 221125_WJC_METTL3_EV_vs_WT_F03.25581.25581.3 3.81E-05 Oct-56 K.GVETIANDVVSLATK[136.11].A "sp|P10515|ODP2_HUMAN,tr|A0A7P0TBE2|A0A7P0TBE2_HUMAN,tr|A0A7P0Z4G4|A0A7P0Z4G4_HUMAN,tr|A0A7P0TAX2|A0A7P0TAX2_HUMAN,tr|A0A7P0TBK2|A0A7P0TBK2_HUMAN,tr|E9PEJ4|E9PEJ4_HUMAN,tr|A0A7P0TAG1|A0A7P0TAG1_HUMAN,tr|A0A7P0TA47|A0A7P0TA47_HUMAN,tr|A0A7P0T997|A0A7P0T997_HUMAN,tr|H0YDD4|H0YDD4_HUMAN" 10 1523.8286 0.99 39827 25581 3 1523.828787 508.9502 "Dihydrolipoyllysine-residue acetyltransferase component of pyruvate dehydrogenase complex, mitochondrial OS=Homo sapiens OX=9606 GN=DLAT PE=1 SV=3" 4.37 3907.7 - 348249 - - - 0.0978 - 1.924 0.449 - 128.2 1 2 0 0.0001 15 0 0 0 2.31E+06 2.34E+06 - - - 5.2534 0.9961 221125_WJC_METTL3_EV_vs_WT_F03.25583.25583.3 0.0357 5/108 R.IFDANTKPNLNLQVLSNPEFLAEGTAIK.D sp|O60701|UGDH_HUMAN 1 3056.6183 3.04 39829 25583 3 3056.624575 1019.88 UDP-glucose 6-dehydrogenase OS=Homo sapiens OX=9606 GN=UGDH PE=1 SV=1 4.68 3908 - 313639 - - - 2.0686 - 1.348 0.326 - 17.7 1 2 0 0.0063 28 0 0 0 6.07E+06 1.99E+06 - - - 2.8598 1 221125_WJC_METTL3_EV_vs_WT_F03.25587.25587.3 3.74E-11 18/84 K.EKPYFPIPEEYTFIQNVPLEDR.V "sp|Q00839|HNRPU_HUMAN,tr|A0A1W2PQL0|A0A1W2PQL0_HUMAN,tr|A0A1W2PPL4|A0A1W2PPL4_HUMAN,tr|A0A1W2PQ74|A0A1W2PQ74_HUMAN,tr|Q5RI18|Q5RI18_HUMAN,tr|A0A1W2PP35|A0A1W2PP35_HUMAN,tr|A0A1W2PPS1|A0A1W2PPS1_HUMAN,tr|A0A1W2PRZ7|A0A1W2PRZ7_HUMAN,tr|A0A1W2PPH7|A0A1W2PPH7_HUMAN,tr|A0A1W2PP34|A0A1W2PP34_HUMAN,tr|A0A1X7SBS1|A0A1X7SBS1_HUMAN" 11 2723.3483 1.32 39832 25587 3 2723.350927 908.79 Heterogeneous nuclear ribonucleoprotein U OS=Homo sapiens OX=9606 GN=HNRNPU PE=1 SV=6 4.25 3908.5 - 3.02E+06 - - - 0.9705 - 3.389 0.642 - 221.2 1 2 0 0.0026 22 0 0 0 1.55E+07 1.17E+07 - - - 8.5906 1 221125_WJC_METTL3_EV_vs_WT_F03.25589.25589.2 2.94E-09 15/36 R.YVASYLLAALGGNSSPSAK[136.11].D sp|P05387|RLA2_HUMAN 1 1875.9822 1.52 39833 25589 2 1875.979568 938.9984 60S acidic ribosomal protein P2 OS=Homo sapiens OX=9606 GN=RPLP2 PE=1 SV=1 8.5 3908.7 - 1.00E+07 - - - -1.3918 - 3.024 0.667 - 555.2 1 2 0 -0.0026 19 0 0 0 5.14E+08 3.38E+08 - - - 6.6872 1 221125_WJC_METTL3_EV_vs_WT_F03.25590.25590.3 0.0153 25/72 R.YVASYLLAALGGNSSPSAK.D sp|P05387|RLA2_HUMAN 1 1867.968 1.42 39834 25590 3 1867.969489 623.6633 60S acidic ribosomal protein P2 OS=Homo sapiens OX=9606 GN=RPLP2 PE=1 SV=1 8.5 3908.8 - 1.79E+07 - - - 0.8084 - 3.796 0.59 - 795.2 1 2 0 0.0015 19 0 0 0 4.73E+08 3.32E+08 - - - 8.3947 0.9999 221125_WJC_METTL3_EV_vs_WT_F03.25592.25592.3 0.000263 15/68 R.EEEEFNTGPLSVLTQSVK[136.11].N "sp|P62316|SMD2_HUMAN,tr|K7ERG4|K7ERG4_HUMAN" 2 2013.9986 1.79 39836 25592 3 2013.999643 672.3401 Small nuclear ribonucleoprotein Sm D2 OS=Homo sapiens OX=9606 GN=SNRPD2 PE=1 SV=1 4.09 3909 - 759884 - - - 0.5094 - 2.491 0.448 - 257.3 1 2 0 0.001 18 0 0 0 2.75E+07 1.54E+07 - - - 5.8071 1 221125_WJC_METTL3_EV_vs_WT_F03.25593.25593.3 6.88E-10 17/68 K.DKPVYDELFYTLSPINGK.L sp|Q9H223|EHD4_HUMAN 1 2098.0623 1.26 39837 25593 3 2098.066591 700.3614 EH domain-containing protein 4 OS=Homo sapiens OX=9606 GN=EHD4 PE=1 SV=1 4.56 3909.1 - 712328 - - - 2.0581 - 3.364 0.58 - 377.9 1 2 0 0.0043 18 0 0 0 1.37E+07 1.08E+07 - - - 8.0261 0.9932 221125_WJC_METTL3_EV_vs_WT_F03.25594.25594.3 3.06E-06 15/76 V.TVNQSLLTPLNLQIDPAIQR.V "sp|P48668|K2C6C_HUMAN,sp|P04259|K2C6B_HUMAN" 2 2233.243 14.79 39838 25594 3 2233.247016 745.4216 "Keratin, type II cytoskeletal 6C OS=Homo sapiens OX=9606 GN=KRT6C PE=1 SV=3" 5.5 3909.2 - 693626 - - - 1.7844 - 2.984 0.449 - 149.8 1 1 0 0.004 20 0 0 0 9.47E+06 6.40E+05 - - - 6.1971 1 221125_WJC_METTL3_EV_vs_WT_F03.25596.25596.3 4.54E-06 17/60 R.ETDLQELFR[166.11]PFGSISR[166.11].L "sp|O75821|EIF3G_HUMAN,tr|K7EP16|K7EP16_HUMAN,tr|K7ENA8|K7ENA8_HUMAN" 3 1913.975 0.76 39840 25596 3 1913.974541 638.9989 Eukaryotic translation initiation factor 3 subunit G OS=Homo sapiens OX=9606 GN=EIF3G PE=1 SV=2 4.68 3909.5 - 667231 - - - -0.2487 - 2.733 0.438 - 405.9 1 2 0 -0.0005 16 0 0 0 2.02E+07 2.66E+07 - - - 6.0029 1 221125_WJC_METTL3_EV_vs_WT_F03.25597.25597.3 1.09E-13 20/112 R.SLEPLPSSGPDFGGLGEEAEFVEVEPEAK.Q sp|Q9Y512|SAM50_HUMAN 1 3015.4237 3.95 39841 25597 3 3015.426661 1006.1485 Sorting and assembly machinery component 50 homolog OS=Homo sapiens OX=9606 GN=SAMM50 PE=1 SV=3 3.72 3909.6 - 636508 - - - 0.9839 - 3.828 0.693 - 265 1 2 0 0.003 29 0 0 0 2.42E+06 6.12E+05 - - - 9.3537 0.9999 221125_WJC_METTL3_EV_vs_WT_F03.25599.25599.3 2.29E-08 17/68 K.DK[136.11]PVYDELFYTLSPINGK[136.11].L sp|Q9H223|EHD4_HUMAN 1 2114.0907 1.26 39843 25599 3 2114.097676 705.7042 EH domain-containing protein 4 OS=Homo sapiens OX=9606 GN=EHD4 PE=1 SV=1 4.56 3909.9 - 465289 - - - 3.3125 - 3.195 0.57 - 296.5 1 2 0 0.007 18 0 0 0 1.37E+07 1.08E+07 - - - 7.7855 1 221125_WJC_METTL3_EV_vs_WT_F03.25603.25603.2 1.08E-12 Dec-36 R.ITEDYYVHLIADNLPVATR[166.11].L "sp|Q92544|TM9S4_HUMAN,tr|A0A0C4DFM1|A0A0C4DFM1_HUMAN" 2 2212.1404 1.04 39847 25603 2 2212.139019 1107.0775 Transmembrane 9 superfamily member 4 OS=Homo sapiens OX=9606 GN=TM9SF4 PE=1 SV=2 4.54 3910.4 - 0 - - - -0.6035 - 2.881 0.746 - 386.8 1 2 0 -0.0013 19 0 0 0 8.16E+06 7.88E+06 - - - 7.152 1 221125_WJC_METTL3_EV_vs_WT_F03.25609.25609.3 7.71E-08 15/72 R.YVASYLLAALGGNSSPSAK[136.11].D sp|P05387|RLA2_HUMAN 1 1875.9822 1.42 39852 25609 3 1875.982355 626.3347 60S acidic ribosomal protein P2 OS=Homo sapiens OX=9606 GN=RPLP2 PE=1 SV=1 8.5 3911.1 - 4.83E+07 - - - 0.0938 - 2.766 0.602 - 225.6 1 2 0 0.0002 19 0 0 0 4.73E+08 3.32E+08 - - - 7.7512 1 221125_WJC_METTL3_EV_vs_WT_F03.25612.25612.2 1.85E-11 16/28 K.DASDDLDDLNFFNQK.K sp|P20042|IF2B_HUMAN 1 1755.7588 0.92 39854 25612 2 1755.758698 878.8867 Eukaryotic translation initiation factor 2 subunit 2 OS=Homo sapiens OX=9606 GN=EIF2S2 PE=1 SV=2 3.66 3911.5 - 979992 - - - -0.0433 - 3.28 0.677 - 992.2 1 2 0 -0.0001 15 0 0 0 6.39E+06 6.98E+06 - - - 6.9617 0.9999 221125_WJC_METTL3_EV_vs_WT_F03.25613.25613.3 0.0415 Dec-76 K.SEVLSESSELLQQELEELRK.S "sp|Q15643|TRIPB_HUMAN,tr|H0YJ97|H0YJ97_HUMAN" 2 2345.1962 1.14 39855 25613 3 2345.192309 782.7393 Thyroid receptor-interacting protein 11 OS=Homo sapiens OX=9606 GN=TRIP11 PE=1 SV=3 4.21 3911.5 - 3.03E+07 - - - -1.6591 - 2.876 0.461 - 117.1 1 2 0 -0.0039 20 0 0 0 3.84E+07 3.37E+07 - - - 6.2415 1 221125_WJC_METTL3_EV_vs_WT_F03.25614.25614.3 1.49E-06 Oct-80 K.FAVQDVNDVLDLEWDQHLEQK.K "sp|P35658|NU214_HUMAN,tr|A0A0A0MSW3|A0A0A0MSW3_HUMAN,tr|A0A494C1F2|A0A494C1F2_HUMAN" 3 2540.2183 0.67 39856 25614 3 2540.214959 847.7467 Nuclear pore complex protein Nup214 OS=Homo sapiens OX=9606 GN=NUP214 PE=1 SV=2 3.96 3911.6 - 1.48E+07 - - - -1.3282 - 2.263 0.54 - 68.2 1 2 0 -0.0034 21 0 0 0 2.64E+07 3.92E+07 - - - 6.5175 1 221125_WJC_METTL3_EV_vs_WT_F03.25616.25616.4 1.76E-05 20/114 K.SEVLSESSELLQQELEELRK.S "sp|Q15643|TRIPB_HUMAN,tr|H0YJ97|H0YJ97_HUMAN" 2 2345.1962 1.06 39858 25616 4 2345.195334 587.3063 Thyroid receptor-interacting protein 11 OS=Homo sapiens OX=9606 GN=TRIP11 PE=1 SV=3 4.21 3911.8 - 7.93E+06 - - - -0.3693 - 3.824 0.557 - 255 1 2 0 -0.0009 20 0 0 0 7.58E+06 7.17E+06 - - - 4.5223 1 221125_WJC_METTL3_EV_vs_WT_F03.25617.25617.4 3.05E-11 26/108 R.TDLEMQIEGLKEELAYLRK.N sp|P08779|K1C16_HUMAN 1 2278.1879 999 39859 25617 4 2278.185434 570.5542 "Keratin, type I cytoskeletal 16 OS=Homo sapiens OX=9606 GN=KRT16 PE=1 SV=4" 4.58 3911.9 - 6.76E+06 - - - -1.0754 - 4.617 0.647 - 747.1 1 2 1 -0.0025 19 0 0 0 2.35E+07 0.00E+00 - - - 5.3743 1 221125_WJC_METTL3_EV_vs_WT_F03.25618.25618.4 3.21E-05 22/114 K.SEVLSESSELLQQELEELR[166.11]K[136.11].S "sp|Q15643|TRIPB_HUMAN,tr|H0YJ97|H0YJ97_HUMAN" 2 2363.2187 -1 39860 25618 4 2363.215395 591.8119 Thyroid receptor-interacting protein 11 OS=Homo sapiens OX=9606 GN=TRIP11 PE=1 SV=3 4.21 3911.9 - 6.71E+06 - - - -1.3858 - 4.032 0.585 - 336.6 1 2 0 -0.0033 20 0 0 0 0.00E+00 0.00E+00 - - - 4.7831 0.9851 221125_WJC_METTL3_EV_vs_WT_F03.25620.25620.3 0.578 17/52 R.NLSTVMDEIHTVLK.K sp|Q8IX12|CCAR1_HUMAN 1 1598.8338 4.73 39862 25620 3 1598.831948 533.9519 Cell division cycle and apoptosis regulator protein 1 OS=Homo sapiens OX=9606 GN=CCAR1 PE=1 SV=2 5.32 3912.1 - 3.76E+06 - - - -1.154 - 1.816 0.133 - 177.2 1 2 0 -0.0018 14 0 0 0 6.53E+06 1.38E+06 - - - 1.6079 1 221125_WJC_METTL3_EV_vs_WT_F03.25623.25623.4 1.11E-06 17/192 K.VLYLGAASGTTVSHVSDIVGPDGLVYAVEFSHR.S "sp|P22087|FBRL_HUMAN,tr|M0R299|M0R299_HUMAN,tr|M0R0P1|M0R0P1_HUMAN,tr|M0QXL5|M0QXL5_HUMAN,tr|M0R2Q4|M0R2Q4_HUMAN" 5 3415.7412 -1 39865 25623 4 3415.738448 854.9426 rRNA 2'-O-methyltransferase fibrillarin OS=Homo sapiens OX=9606 GN=FBL PE=1 SV=2 5.21 3912.4 - 2.95E+06 - - - -0.8118 - 3.136 0.504 - 111.8 1 2 0 -0.0028 33 0 0 0 0.00E+00 0.00E+00 - - - 3.955 1 221125_WJC_METTL3_EV_vs_WT_F03.25628.25628.2 1.88E-13 16/36 K.LGGTIDDC[160.03]ELVEGLVLTQK[136.11].V sp|P50991|TCPD_HUMAN 1 2067.0649 -1 39870 25628 2 2067.058449 1034.5397 T-complex protein 1 subunit delta OS=Homo sapiens OX=9606 GN=CCT4 PE=1 SV=4 3.92 3913.1 - 1.15E+06 - - - -3.1315 - 3.81 0.71 - 875.3 1 2 0 -0.0065 19 0 0 0 0.00E+00 0.00E+00 - - - 7.5717 0.9617 221125_WJC_METTL3_EV_vs_WT_F03.25629.25629.4 0.0147 10/102 K.ASIKDVLDSEGYLLFYHK.Q "sp|A6NNY8|UBP27_HUMAN,sp|Q9UPT9|UBP22_HUMAN" 2 2097.0783 -1 39871 25629 4 2097.075706 525.2768 Ubiquitin carboxyl-terminal hydrolase 27 OS=Homo sapiens OX=9606 GN=USP27X PE=1 SV=3 5.38 3913.2 - 1.08E+06 - - - -1.2165 - 2.014 0.196 - 56.2 1 2 1 -0.0026 18 0 0 0 0.00E+00 0.00E+00 - - - 1.1711 1 221125_WJC_METTL3_EV_vs_WT_F03.25630.25630.3 1.48E-05 14/52 R.NLSTVMDEIHTVLK[136.11].K sp|Q8IX12|CCAR1_HUMAN 1 1606.848 -1 39872 25630 3 1606.847563 536.6233 Cell division cycle and apoptosis regulator protein 1 OS=Homo sapiens OX=9606 GN=CCAR1 PE=1 SV=2 5.32 3913.4 - 1.04E+06 - - - -0.2676 - 2.329 0.492 - 180 1 2 0 -0.0004 14 0 0 0 0.00E+00 0.00E+00 - - - 6.272 1 221125_WJC_METTL3_EV_vs_WT_F03.25633.25633.2 4.05E-08 Sep-42 R.K[136.11]PLVIIAEDVDGEALSTLVLNR[166.11].L "sp|P10809|CH60_HUMAN,tr|A0A7I2V2X6|A0A7I2V2X6_HUMAN,tr|A0A7I2YQK6|A0A7I2YQK6_HUMAN,tr|A0A7I2V599|A0A7I2V599_HUMAN,tr|A0A7I2YQ71|A0A7I2YQ71_HUMAN,tr|A0A7I2V5M1|A0A7I2V5M1_HUMAN,tr|A0A7I2V5K3|A0A7I2V5K3_HUMAN" 7 2382.3489 -1 39874 25633 2 2382.346623 1192.1817 "60 kDa heat shock protein, mitochondrial OS=Homo sapiens OX=9606 GN=HSPD1 PE=1 SV=2" 4.32 3913.7 - 0 - - - -0.9545 - 2.427 0.633 - 155.3 1 2 0 -0.0023 22 0 0 0 0.00E+00 0.00E+00 - - - 5.8955 0.974 221125_WJC_METTL3_EV_vs_WT_F03.25634.25634.2 0.0323 14/28 K.K[136.11]VSQEILELLNTTTA.K "sp|Q86U44|MTA70_HUMAN,tr|H0YFV6|H0YFV6_HUMAN" 2 1666.9233 0.02 39875 25634 2 1666.918291 834.4689 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 4.53 3913.7 - 2.62E+06 - - - -2.9851 - 2.979 0.473 - 802.6 1 1 0 -0.005 15 0 0 0 2.13E+06 1.10E+08 - - - 5.2167 1 221125_WJC_METTL3_EV_vs_WT_F03.25635.25635.2 1.06E-10 16/38 K.NTAPLTLC[160.03]PLNIGSQGSTDY.- sp|P19474|RO52_HUMAN 1 2121.0048 - 39876 25635 2 2120.998009 1061.5097 E3 ubiquitin-protein ligase TRIM21 OS=Homo sapiens OX=9606 GN=TRIM21 PE=1 SV=1 3.8 3913.9 - 913727 - - - -3.2183 - 3.17 0.688 - 536.4 1 2 0 -0.0068 20 0 0 0 - - - - - 6.9569 1 221125_WJC_METTL3_EV_vs_WT_F03.25637.25637.4 1.56E-07 16/96 K.VVVHPLVLLSVVDHFNR[166.11].L "sp|P51665|PSMD7_HUMAN,tr|H3BNT7|H3BNT7_HUMAN,tr|H3BQV2|H3BQV2_HUMAN,tr|H3BTM8|H3BTM8_HUMAN" 4 1952.1235 0.34 39878 25637 4 1952.121857 489.0382 26S proteasome non-ATPase regulatory subunit 7 OS=Homo sapiens OX=9606 GN=PSMD7 PE=1 SV=2 6.89 3914.1 - 0 - - - -0.8529 - 2.536 0.557 - 87.4 1 2 0 -0.0017 17 0 0 0 4.92E+05 1.43E+06 - - - 4.3968 1 221125_WJC_METTL3_EV_vs_WT_F03.25643.25643.3 1.49E-10 31/72 R.TDLEMQIEGLKEELAYLRK.N sp|P08779|K1C16_HUMAN 1 2278.1879 51.74 39882 25643 3 2278.189423 760.4032 "Keratin, type I cytoskeletal 16 OS=Homo sapiens OX=9606 GN=KRT16 PE=1 SV=4" 4.58 3914.9 - 492334 - - - 0.6755 - 5.024 0.599 - 1491.6 1 2 1 0.0015 19 0 0 0 1.18E+07 2.28E+05 - - - 9.1837 1 221125_WJC_METTL3_EV_vs_WT_F03.25644.25644.3 4.44E-14 24/72 K.SDLEMQYETLQEELMALKK.N "sp|P35527|K1C9_HUMAN,tr|K7EQQ3|K7EQQ3_HUMAN" 2 2298.1123 999 39883 25644 3 2298.112309 767.0447 "Keratin, type I cytoskeletal 9 OS=Homo sapiens OX=9606 GN=KRT9 PE=1 SV=3" 4.25 3915 - 1.89E+06 - - - -0.0117 - 4.452 0.675 - 1009.6 1 2 0 0 19 0 0 0 6.21E+07 0.00E+00 - - - 9.7344 1 221125_WJC_METTL3_EV_vs_WT_F03.25647.25647.3 6.03E-07 20/80 K.TVLGTPEVLLGALPGAGGTQR[166.11].L "sp|P40939|ECHA_HUMAN,tr|A0A2R8YG21|A0A2R8YG21_HUMAN,tr|A0A2R8Y688|A0A2R8Y688_HUMAN,tr|H0YFD6|H0YFD6_HUMAN" 4 2016.1243 1.1 39886 25647 3 2016.123224 673.0487 "Trifunctional enzyme subunit alpha, mitochondrial OS=Homo sapiens OX=9606 GN=HADHA PE=1 SV=2" 5.66 3915.2 - 858045 - - - -0.5387 - 3.24 0.548 - 292.1 1 2 0 -0.0011 21 0 0 0 6.21E+06 5.63E+06 - - - 7.4677 1 221125_WJC_METTL3_EV_vs_WT_F03.25648.25648.3 5.06E-07 26/96 R.SINTEVVAC[160.03]SVDSQFTHLAWINTPR.R "sp|Q13162|PRDX4_HUMAN,tr|A6NJJ0|A6NJJ0_HUMAN,tr|H7C3T4|H7C3T4_HUMAN" 3 2844.3865 -1 39887 25648 3 2844.383083 949.1361 Peroxiredoxin-4 OS=Homo sapiens OX=9606 GN=PRDX4 PE=1 SV=1 5.3 3915.4 - 765338 - - - -1.1936 - 4.635 0.694 - 690.3 1 2 0 -0.0034 25 0 0 0 0.00E+00 0.00E+00 - - - 9.8048 0.9999 221125_WJC_METTL3_EV_vs_WT_F03.25652.25652.3 3.36E-08 18/56 R.TKDDIIIC[160.03]EIGDVFK.A sp|Q9Y512|SAM50_HUMAN 1 1764.8968 1.91 39891 25652 3 1764.895307 589.3062 Sorting and assembly machinery component 50 homolog OS=Homo sapiens OX=9606 GN=SAMM50 PE=1 SV=3 4.23 3915.9 - 659369 - - - -0.8391 - 3.415 0.566 - 605.2 1 2 1 -0.0015 15 0 0 0 5.12E+06 2.68E+06 - - - 8.0547 1 221125_WJC_METTL3_EV_vs_WT_F03.25654.25654.2 3.45E-12 16/34 R.EEEEFNTGPLSVLTQSVK[136.11].N "sp|P62316|SMD2_HUMAN,tr|K7ERG4|K7ERG4_HUMAN" 2 2013.9986 2.57 39893 25654 2 2013.998846 1008.0066 Small nuclear ribonucleoprotein Sm D2 OS=Homo sapiens OX=9606 GN=SNRPD2 PE=1 SV=1 4.09 3916.2 - 504092 - - - 0.1137 - 3.296 0.669 - 844.1 1 2 0 0.0002 18 0 0 0 1.41E+07 5.49E+06 - - - 6.9145 0.9999 221125_WJC_METTL3_EV_vs_WT_F03.25655.25655.3 2.66E-09 16/56 R.TK[136.11]DDIIIC[160.03]EIGDVFK[136.11].A sp|Q9Y512|SAM50_HUMAN 1 1780.9252 1.86 39894 25655 3 1780.922435 594.649 Sorting and assembly machinery component 50 homolog OS=Homo sapiens OX=9606 GN=SAMM50 PE=1 SV=3 4.23 3916.3 - 384182 - - - -1.5458 - 3.372 0.596 - 598.4 1 2 1 -0.0028 15 0 0 0 5.00E+06 2.68E+06 - - - 8.3557 1 221125_WJC_METTL3_EV_vs_WT_F03.25663.25663.3 5.80E-07 19/72 R.ATAFNEQVDKFFPLIEVNK.V sp|P27694|RFA1_HUMAN 1 2209.1419 1.01 39900 25663 3 2209.139204 737.3879 Replication protein A 70 kDa DNA-binding subunit OS=Homo sapiens OX=9606 GN=RPA1 PE=1 SV=2 4.68 3917.2 - 2.93E+06 - - - -1.2294 - 3.677 0.613 - 389.5 1 2 1 -0.0027 19 0 0 0 3.13E+07 3.11E+07 - - - 8.5726 1 221125_WJC_METTL3_EV_vs_WT_F03.25664.25664.3 6.01E-12 18/72 K.HDELADSLPC[160.03]AEGEFIFLR.L sp|Q9H0D6|XRN2_HUMAN 1 2218.0365 1.16 39901 25664 3 2218.032069 740.3528 5'-3' exoribonuclease 2 OS=Homo sapiens OX=9606 GN=XRN2 PE=1 SV=1 4.17 3917.3 - 2.88E+06 - - - -1.9837 - 3.694 0.653 - 591.8 1 2 0 -0.0044 19 0 0 0 1.17E+07 1.01E+07 - - - 9.0294 1 221125_WJC_METTL3_EV_vs_WT_F03.25665.25665.4 1.29E-13 29/186 K.PAPGTLGTGLGAGFGTALGAGQASLFGNNQPK.L "sp|P52948|NUP98_HUMAN,tr|A0A3B3ITD8|A0A3B3ITD8_HUMAN,tr|H0YEN4|H0YEN4_HUMAN" 3 2926.4937 1.79 39902 25665 4 2926.490209 732.6307 Nuclear pore complex protein Nup98-Nup96 OS=Homo sapiens OX=9606 GN=NUP98 PE=1 SV=4 9.18 3917.4 - 2.32E+06 - - - -1.1997 - 4.965 0.633 - 455.3 1 1 0 -0.0035 32 0 0 0 9.14E+06 5.10E+06 - - - 5.2185 1 221125_WJC_METTL3_EV_vs_WT_F03.25668.25668.3 6.44E-07 20/100 K.AATTEPTEVEEVVPALEPTETLLSEK.E "sp|Q9BXK5|B2L13_HUMAN,tr|A0A087WX97|A0A087WX97_HUMAN,tr|A0A087WTL4|A0A087WTL4_HUMAN" 3 2782.4012 2.23 39905 25668 3 2782.398342 928.4743 Bcl-2-like protein 13 OS=Homo sapiens OX=9606 GN=BCL2L13 PE=1 SV=1 3.83 3917.7 - 542518 - - - -1.0157 - 3.512 0.58 - 251.6 1 2 0 -0.0028 26 0 0 0 1.29E+07 5.80E+06 - - - 7.8957 1 221125_WJC_METTL3_EV_vs_WT_F03.25670.25670.3 7.07E-07 14/56 K.GLAPDLPEDLYHLIK[136.11].K "sp|P62277|RS13_HUMAN,tr|J3KMX5|J3KMX5_HUMAN" 2 1700.9229 1.45 39907 25670 3 1700.921331 567.9816 40S ribosomal protein S13 OS=Homo sapiens OX=9606 GN=RPS13 PE=1 SV=2 4.54 3918 - 455692 - - - -0.9066 - 2.478 0.512 - 201.9 1 2 0 -0.0015 15 0 0 0 6.48E+06 4.46E+06 - - - 6.6157 0.9997 221125_WJC_METTL3_EV_vs_WT_F03.25671.25671.2 0.000109 30-Nov R.QNLEPLFEQYINNLRR.Q "sp|P48668|K2C6C_HUMAN,sp|P04259|K2C6B_HUMAN,sp|P13647|K2C5_HUMAN,sp|P02538|K2C6A_HUMAN,tr|F8W0C6|F8W0C6_HUMAN" 5 2046.0647 999 39908 25671 2 2046.062646 1024.0396 "Keratin, type II cytoskeletal 6C OS=Homo sapiens OX=9606 GN=KRT6C PE=1 SV=3" 6.14 3918.1 - 420738 - - - -0.9907 - 1.956 0.399 - 108.8 1 2 0 -0.002 16 0 0 0 1.66E+07 0.00E+00 - - - 3.6368 1 221125_WJC_METTL3_EV_vs_WT_F03.25672.25672.3 6.40E-08 20/60 K.KVIEASDVVLEVLDAR.D sp|Q9BVP2|GNL3_HUMAN 1 1754.9778 0.69 39909 25672 3 1754.977046 585.9999 Guanine nucleotide-binding protein-like 3 OS=Homo sapiens OX=9606 GN=GNL3 PE=1 SV=2 4.32 3918.2 - 410831 - - - -0.4382 - 3.702 0.577 - 563.6 1 2 0 -0.0008 16 0 0 0 2.78E+06 4.04E+06 - - - 8.3312 0.9998 221125_WJC_METTL3_EV_vs_WT_F03.25685.25685.3 0.000118 Jul-68 K.INISQVIAVVGQQNVEGK[136.11].R "sp|P24928|RPB1_HUMAN,tr|A0A6Q8PGB0|A0A6Q8PGB0_HUMAN" 2 1903.0618 1.5 39920 25685 3 1903.057444 635.3612 DNA-directed RNA polymerase II subunit RPB1 OS=Homo sapiens OX=9606 GN=POLR2A PE=1 SV=2 6 3919.5 - 1.19E+06 - - - -2.3026 - 1.561 0.496 - 54.6 1 2 0 -0.0044 18 0 0 0 1.31E+07 8.73E+06 - - - 5.1776 1 221125_WJC_METTL3_EV_vs_WT_F03.25686.25686.4 5.05E-06 14/90 R.QNLEPLFEQYINNLRR.Q "sp|P48668|K2C6C_HUMAN,sp|P04259|K2C6B_HUMAN,sp|P13647|K2C5_HUMAN,sp|P02538|K2C6A_HUMAN,tr|F8W0C6|F8W0C6_HUMAN" 5 2046.0647 999 39921 25686 4 2046.061052 512.5234 "Keratin, type II cytoskeletal 6C OS=Homo sapiens OX=9606 GN=KRT6C PE=1 SV=3" 6.14 3919.6 - 1.01E+06 - - - -1.7697 - 2.749 0.531 - 194.5 1 2 0 -0.0036 16 0 0 0 6.34E+06 0.00E+00 - - - 4.203 1 221125_WJC_METTL3_EV_vs_WT_F03.25696.25696.3 1.85E-06 20/64 K.LMSSLPNFC[160.03]GIFNHLER.L "sp|Q96PU8|QKI_HUMAN,tr|H0YFB7|H0YFB7_HUMAN" 2 2033.9815 3.03 39929 25696 3 2033.982168 679.0011 Protein quaking OS=Homo sapiens OX=9606 GN=QKI PE=1 SV=1 6.74 3920.6 - 1.87E+06 - - - 0.3102 - 3.262 0.619 - 392.6 1 2 0 0.0006 17 0 0 0 1.77E+07 5.84E+06 - - - 8.428 1 221125_WJC_METTL3_EV_vs_WT_F03.25698.25698.3 6.23E-09 21/80 K.RPLEATFDLGIPQAVLPPLPK.R "sp|Q9NR56|MBNL1_HUMAN,tr|Q86VM6|Q86VM6_HUMAN,tr|A0A0A0MQX8|A0A0A0MQX8_HUMAN,tr|C9JP00|C9JP00_HUMAN" 4 2271.2991 1.9 39931 25698 3 2271.296399 758.107 Muscleblind-like protein 1 OS=Homo sapiens OX=9606 GN=MBNL1 PE=1 SV=2 6.07 3920.9 - 1.62E+06 - - - -1.1848 - 3.138 0.62 - 502.2 1 2 0 -0.0027 21 0 0 0 6.59E+07 3.47E+07 - - - 8.1933 1 221125_WJC_METTL3_EV_vs_WT_F03.25699.25699.3 4.34E-10 28/112 K.MK[136.11]EIAEAYLGYPVTNAVITVPAYFNDSQR[166.11].Q "sp|P0DMV8|HS71A_HUMAN,sp|P0DMV9|HS71B_HUMAN,tr|A0A0G2JIW1|A0A0G2JIW1_HUMAN" 3 3277.6448 0.11 39932 25699 3 3277.637959 1093.5556 Heat shock 70 kDa protein 1A OS=Homo sapiens OX=9606 GN=HSPA1A PE=1 SV=1 4.68 3921 - 1.46E+06 - - - -2.0936 - 4.248 0.625 - 444.1 1 2 1 -0.0069 29 0 0 0 1.11E+07 1.00E+08 - - - 8.834 1 221125_WJC_METTL3_EV_vs_WT_F03.25712.25712.3 4.32E-14 22/88 R.TMMAC[160.03]GGSIQTSVNALSADVLGR[166.11].C sp|Q99832|TCPH_HUMAN 1 2348.1162 0.31 39943 25712 3 2348.112025 783.7127 T-complex protein 1 subunit eta OS=Homo sapiens OX=9606 GN=CCT7 PE=1 SV=2 5.5 3922.2 - 3.39E+06 - - - -1.7806 - 3.727 0.723 - 498.2 1 2 0 -0.0042 23 0 0 0 1.30E+07 4.12E+07 - - - 9.6859 1 221125_WJC_METTL3_EV_vs_WT_F03.25714.25714.2 1.38E-10 20/34 R.SQLDLFDDVGTFASGPPK.Y "sp|Q8N6H7|ARFG2_HUMAN,tr|E9PQP3|E9PQP3_HUMAN,tr|H0YDN9|H0YDN9_HUMAN,tr|G5E9L0|G5E9L0_HUMAN,tr|A0A0D9SF70|A0A0D9SF70_HUMAN" 5 1892.9156 1.23 39945 25714 2 1892.906967 947.4651 ADP-ribosylation factor GTPase-activating protein 2 OS=Homo sapiens OX=9606 GN=ARFGAP2 PE=1 SV=1 3.93 3922.4 - 2.55E+06 - - - -4.5654 - 4.379 0.642 - 1098.3 1 2 0 -0.0086 18 0 0 0 3.77E+07 3.08E+07 - - - 7.4109 1 221125_WJC_METTL3_EV_vs_WT_F03.25715.25715.3 1.89E-12 19/68 R.SQLDLFDDVGTFASGPPK[136.11].Y "sp|Q8N6H7|ARFG2_HUMAN,tr|E9PQP3|E9PQP3_HUMAN,tr|H0YDN9|H0YDN9_HUMAN,tr|G5E9L0|G5E9L0_HUMAN,tr|A0A0D9SF70|A0A0D9SF70_HUMAN" 5 1900.9298 1.31 39946 25715 3 1900.922654 634.6505 ADP-ribosylation factor GTPase-activating protein 2 OS=Homo sapiens OX=9606 GN=ARFGAP2 PE=1 SV=1 3.93 3922.4 - 2.54E+06 - - - -3.7639 - 3.397 0.656 - 480.9 1 2 0 -0.0072 18 0 0 0 3.32E+07 2.54E+07 - - - 8.8969 1 221125_WJC_METTL3_EV_vs_WT_F03.25717.25717.3 7.52E-09 28/60 R.RGVMLAVDAVIAELKK.Q "sp|P10809|CH60_HUMAN,tr|A0A7I2V2X6|A0A7I2V2X6_HUMAN,tr|A0A7I2V599|A0A7I2V599_HUMAN,tr|E7EXB4|E7EXB4_HUMAN,tr|A0A7I2YQ71|A0A7I2YQ71_HUMAN,tr|E7ESH4|E7ESH4_HUMAN,tr|A0A7I2V5M1|A0A7I2V5M1_HUMAN,tr|A0A7I2V5K3|A0A7I2V5K3_HUMAN,tr|A0A7I2V369|A0A7I2V369_HUMAN" 9 1712.0019 1.21 39948 25717 3 1711.999007 571.6746 "60 kDa heat shock protein, mitochondrial OS=Homo sapiens OX=9606 GN=HSPD1 PE=1 SV=2" 8.59 3922.7 - 1.42E+06 - - - -1.6676 - 4.655 0.568 - 1284.5 1 2 0 -0.0029 16 0 0 0 1.21E+08 1.01E+08 - - - 8.818 1 221125_WJC_METTL3_EV_vs_WT_F03.25727.25727.3 7.76E-09 15/80 K.R[166.11]PLEATFDLGIPQAVLPPLPK[136.11].R "sp|Q9NR56|MBNL1_HUMAN,tr|Q86VM6|Q86VM6_HUMAN,tr|A0A0A0MQX8|A0A0A0MQX8_HUMAN,tr|C9JP00|C9JP00_HUMAN" 4 2289.3216 1.9 39956 25727 3 2289.317008 764.1145 Muscleblind-like protein 1 OS=Homo sapiens OX=9606 GN=MBNL1 PE=1 SV=2 6.07 3923.7 - 4.72E+06 - - - -1.9884 - 2.675 0.665 - 169.9 1 2 0 -0.0046 21 0 0 0 6.59E+07 3.47E+07 - - - 8.3118 1 221125_WJC_METTL3_EV_vs_WT_F03.25728.25728.2 4.73E-09 20/34 R.SQLDLFDDVGTFASGPPK[136.11].Y "sp|Q8N6H7|ARFG2_HUMAN,tr|E9PQP3|E9PQP3_HUMAN,tr|H0YDN9|H0YDN9_HUMAN,tr|G5E9L0|G5E9L0_HUMAN,tr|A0A0D9SF70|A0A0D9SF70_HUMAN" 5 1900.9298 1.23 39957 25728 2 1900.92311 951.4722 ADP-ribosylation factor GTPase-activating protein 2 OS=Homo sapiens OX=9606 GN=ARFGAP2 PE=1 SV=1 3.93 3923.8 - 3.83E+06 - - - -3.5241 - 3.95 0.684 - 1005 1 2 0 -0.0067 18 0 0 0 3.77E+07 3.08E+07 - - - 7.4683 1 221125_WJC_METTL3_EV_vs_WT_F03.25729.25729.4 7.49E-10 24/90 R.RGVMLAVDAVIAELKK.Q "sp|P10809|CH60_HUMAN,tr|A0A7I2V2X6|A0A7I2V2X6_HUMAN,tr|A0A7I2V599|A0A7I2V599_HUMAN,tr|E7EXB4|E7EXB4_HUMAN,tr|A0A7I2YQ71|A0A7I2YQ71_HUMAN,tr|E7ESH4|E7ESH4_HUMAN,tr|A0A7I2V5M1|A0A7I2V5M1_HUMAN,tr|A0A7I2V5K3|A0A7I2V5K3_HUMAN,tr|A0A7I2V369|A0A7I2V369_HUMAN" 9 1712.0019 1.23 39958 25729 4 1711.996427 429.0077 "60 kDa heat shock protein, mitochondrial OS=Homo sapiens OX=9606 GN=HSPD1 PE=1 SV=2" 8.59 3923.8 - 3.66E+06 - - - -3.1746 - 3.415 0.607 - 538 1 2 0 -0.0054 16 0 0 0 5.98E+07 4.88E+07 - - - 4.9405 0.9994 221125_WJC_METTL3_EV_vs_WT_F03.25730.25730.4 2.95E-06 19/90 R.R[166.11]GVMLAVDAVIAELK[136.11]K[136.11].Q "sp|P10809|CH60_HUMAN,tr|A0A7I2V2X6|A0A7I2V2X6_HUMAN,tr|A0A7I2V599|A0A7I2V599_HUMAN,tr|E7EXB4|E7EXB4_HUMAN,tr|A0A7I2YQ71|A0A7I2YQ71_HUMAN,tr|E7ESH4|E7ESH4_HUMAN,tr|A0A7I2V5M1|A0A7I2V5M1_HUMAN,tr|A0A7I2V5K3|A0A7I2V5K3_HUMAN,tr|A0A7I2V369|A0A7I2V369_HUMAN" 9 1738.0385 1.23 39959 25730 4 1738.032313 435.5169 "60 kDa heat shock protein, mitochondrial OS=Homo sapiens OX=9606 GN=HSPD1 PE=1 SV=2" 8.59 3923.9 - 3.14E+06 - - - -3.5782 - 3.027 0.391 - 351.1 1 2 0 -0.0062 16 0 0 0 5.98E+07 4.88E+07 - - - 3.0177 0.9975 221125_WJC_METTL3_EV_vs_WT_F03.25732.25732.2 0.0398 May-40 K.R[166.11]PLEATFDLGIPQAVLPPLPK[136.11].R "sp|Q9NR56|MBNL1_HUMAN,tr|Q86VM6|Q86VM6_HUMAN,tr|A0A0A0MQX8|A0A0A0MQX8_HUMAN,tr|C9JP00|C9JP00_HUMAN" 4 2289.3216 -1 39961 25732 2 2289.31671 1145.6681 Muscleblind-like protein 1 OS=Homo sapiens OX=9606 GN=MBNL1 PE=1 SV=2 6.07 3924.1 - 1.29E+06 - - - -2.1185 - 1.223 0.377 - 37.4 1 2 0 -0.0049 21 0 0 0 0.00E+00 0.00E+00 - - - 2.3189 0.9984 221125_WJC_METTL3_EV_vs_WT_F03.25733.25733.2 0.00613 30-Aug R.RGVMLAVDAVIAELKK.Q "sp|P10809|CH60_HUMAN,tr|A0A7I2V2X6|A0A7I2V2X6_HUMAN,tr|A0A7I2V599|A0A7I2V599_HUMAN,tr|E7EXB4|E7EXB4_HUMAN,tr|A0A7I2YQ71|A0A7I2YQ71_HUMAN,tr|E7ESH4|E7ESH4_HUMAN,tr|A0A7I2V5M1|A0A7I2V5M1_HUMAN,tr|A0A7I2V5K3|A0A7I2V5K3_HUMAN,tr|A0A7I2V369|A0A7I2V369_HUMAN" 9 1712.0019 4.12 39962 25733 2 1711.998433 857.0082 "60 kDa heat shock protein, mitochondrial OS=Homo sapiens OX=9606 GN=HSPD1 PE=1 SV=2" 8.59 3924.3 - 1.14E+06 - - - -2.0029 - 1.567 0.339 - 117.2 1 2 0 -0.0034 16 0 0 0 5.48E+06 1.33E+06 - - - 2.6481 1 221125_WJC_METTL3_EV_vs_WT_F03.25734.25734.3 5.72E-07 Dec-72 R.SLEGGNFIAGVLIQGTQER.M "sp|P58107|EPIPL_HUMAN,tr|A0A075B730|A0A075B730_HUMAN" 2 1988.0327 0.3 39963 25734 3 1988.029015 663.6848 Epiplakin OS=Homo sapiens OX=9606 GN=EPPK1 PE=1 SV=3 4.53 3924.4 - 429955 - - - -1.8556 - 2.999 0.507 - 149 1 2 0 -0.0037 19 0 0 0 4.99E+06 1.65E+07 - - - 6.8898 1 221125_WJC_METTL3_EV_vs_WT_F03.25737.25737.3 3.52E-06 26/60 R.R[166.11]GVMLAVDAVIAELK[136.11]K[136.11].Q "sp|P10809|CH60_HUMAN,tr|A0A7I2V2X6|A0A7I2V2X6_HUMAN,tr|A0A7I2V599|A0A7I2V599_HUMAN,tr|E7EXB4|E7EXB4_HUMAN,tr|A0A7I2YQ71|A0A7I2YQ71_HUMAN,tr|E7ESH4|E7ESH4_HUMAN,tr|A0A7I2V5M1|A0A7I2V5M1_HUMAN,tr|A0A7I2V5K3|A0A7I2V5K3_HUMAN,tr|A0A7I2V369|A0A7I2V369_HUMAN" 9 1738.0385 1.21 39964 25737 3 1738.033957 580.3535 "60 kDa heat shock protein, mitochondrial OS=Homo sapiens OX=9606 GN=HSPD1 PE=1 SV=2" 8.59 3924.8 - 5.70E+06 - - - -2.6323 - 4.346 0.672 - 1052.9 1 2 0 -0.0046 16 0 0 0 1.21E+08 1.01E+08 - - - 9.8008 0.9993 221125_WJC_METTL3_EV_vs_WT_F03.25739.25739.4 1.09E-10 30/168 K.MK[136.11]EIAEAYLGYPVTNAVITVPAYFNDSQR[166.11].Q "sp|P0DMV8|HS71A_HUMAN,sp|P0DMV9|HS71B_HUMAN,tr|A0A0G2JIW1|A0A0G2JIW1_HUMAN" 3 3277.6448 0.08 39966 25739 4 3277.629319 820.4185 Heat shock 70 kDa protein 1A OS=Homo sapiens OX=9606 GN=HSPA1A PE=1 SV=1 4.68 3925 - 2.65E+06 - - - -4.7296 - 3.994 0.578 - 341.4 1 2 1 -0.0155 29 0 0 0 3.27E+06 4.32E+07 - - - 4.6794 0.9994 221125_WJC_METTL3_EV_vs_WT_F03.25743.25743.3 5.89E-09 18/92 R.LEQQVPVNQVFGQDEMIDVIGVTK[136.11].G "sp|P39023|RL3_HUMAN,tr|G5E9G0|G5E9G0_HUMAN,tr|H7C3M2|H7C3M2_HUMAN,tr|B5MCW2|B5MCW2_HUMAN,tr|H7C422|H7C422_HUMAN" 5 2693.3826 0.99 39968 25743 3 2694.381172 898.8015 60S ribosomal protein L3 OS=Homo sapiens OX=9606 GN=RPL3 PE=1 SV=2 3.92 3925.7 - 998475 - - - 370.762 - 3.794 0.56 - 396.9 1 2 0 0.9986 24 0 0 0 2.26E+07 2.28E+07 - - - 7.6038 1 221125_WJC_METTL3_EV_vs_WT_F03.25744.25744.3 6.49E-06 18/64 K.QLNDLWDQIEQAHLELR.T sp|Q99459|CDC5L_HUMAN 1 2120.0651 1.67 39969 25744 3 2120.068078 707.6956 Cell division cycle 5-like protein OS=Homo sapiens OX=9606 GN=CDC5L PE=1 SV=2 4.31 3925.8 - 1.79E+06 - - - 1.4202 - 3.007 0.514 - 570.3 1 2 0 0.003 17 0 0 0 6.29E+06 3.78E+06 - - - 7.0511 0.9999 221125_WJC_METTL3_EV_vs_WT_F03.25746.25746.3 7.19E-09 21/96 K.SGFEPASLKEEVGEEAIVELVENGK.K "sp|P35579|MYH9_HUMAN,tr|Q5BKV1|Q5BKV1_HUMAN,tr|B1AH99|B1AH99_HUMAN" 3 2659.3229 1.74 39971 25746 3 2659.318834 887.4482 Myosin-9 OS=Homo sapiens OX=9606 GN=MYH9 PE=1 SV=4 4.11 3926 - 1.10E+06 - - - -1.5132 - 4.154 0.551 - 349.6 1 2 1 -0.004 25 0 0 0 8.89E+06 5.11E+06 - - - 7.9583 1 221125_WJC_METTL3_EV_vs_WT_F03.25750.25750.4 4.47E-14 43/258 R.FGGFGGPGGVGGLGGPGGFGPGGYPGGIHEVSVNQSLLQPLNVK.V sp|P35908|K22E_HUMAN 1 4091.0653 26.75 39973 25750 4 4091.057641 1023.7736 "Keratin, type II cytoskeletal 2 epidermal OS=Homo sapiens OX=9606 GN=KRT2 PE=1 SV=2" 6.75 3926.5 - 8.76E+06 - - - -1.8841 - 5.757 0.668 - 454.3 1 2 0 -0.0077 44 0 0 0 1.93E+08 7.22E+06 - - - 5.5341 1 221125_WJC_METTL3_EV_vs_WT_F03.25751.25751.3 2.60E-19 30/104 K.VDEFPLC[160.03]GHMVSDEYEQLSSEALEAAR.L "sp|P27635|RL10_HUMAN,tr|A6QRI9|A6QRI9_HUMAN,tr|B8A6G2|B8A6G2_HUMAN,tr|X1WI28|X1WI28_HUMAN" 4 3081.3696 1.24 39974 25751 3 3081.371351 1028.1305 60S ribosomal protein L10 OS=Homo sapiens OX=9606 GN=RPL10 PE=1 SV=4 4 3926.7 - 3.84E+06 - - - 0.579 - 5.322 0.77 - 664.7 1 2 0 0.0018 27 0 0 0 2.51E+07 2.02E+07 - - - 10.9706 1 221125_WJC_METTL3_EV_vs_WT_F03.25752.25752.3 2.78E-14 29/172 R.FGGFGGPGGVGGLGGPGGFGPGGYPGGIHEVSVNQSLLQPLNVK.V sp|P35908|K22E_HUMAN 1 4091.0653 64.65 39975 25752 3 4091.058805 1364.6957 "Keratin, type II cytoskeletal 2 epidermal OS=Homo sapiens OX=9606 GN=KRT2 PE=1 SV=2" 6.75 3926.8 - 2.21E+06 - - - -1.5996 - 4.752 0.706 - 264.1 1 2 0 -0.0065 44 0 0 0 4.33E+07 6.70E+05 - - - 9.9951 1 221125_WJC_METTL3_EV_vs_WT_F03.25753.25753.3 2.76E-09 17/92 R.LEQQVPVNQVFGQDEMIDVIGVTK.G "sp|P39023|RL3_HUMAN,tr|G5E9G0|G5E9G0_HUMAN,tr|H7C3M2|H7C3M2_HUMAN,tr|B5MCW2|B5MCW2_HUMAN,tr|H7C422|H7C422_HUMAN" 5 2685.3684 0.99 39976 25753 3 2685.361164 896.1301 60S ribosomal protein L3 OS=Homo sapiens OX=9606 GN=RPL3 PE=1 SV=2 3.92 3926.9 - 2.05E+06 - - - -2.6827 - 3.902 0.604 - 332.8 1 2 0 -0.0072 24 0 0 0 2.26E+07 2.28E+07 - - - 8.4342 1 221125_WJC_METTL3_EV_vs_WT_F03.25754.25754.3 3.13E-15 29/112 K.MKEIAEAYLGYPVTNAVITVPAYFNDSQR.Q "sp|P0DMV8|HS71A_HUMAN,sp|P0DMV9|HS71B_HUMAN,tr|A0A0G2JIW1|A0A0G2JIW1_HUMAN" 3 3259.6224 0.11 39977 25754 3 3259.612898 1087.5481 Heat shock 70 kDa protein 1A OS=Homo sapiens OX=9606 GN=HSPA1A PE=1 SV=1 4.68 3927 - 1.25E+06 - - - -2.9 - 4.982 0.721 - 351.8 1 2 1 -0.0095 29 0 0 0 1.11E+07 1.01E+08 - - - 10.2703 0.9999 221125_WJC_METTL3_EV_vs_WT_F03.25755.25755.3 4.15E-09 17/68 K.IISSDRDLLAVVFYGTEK.D "sp|P12956|XRCC6_HUMAN,tr|B1AHC9|B1AHC9_HUMAN" 2 2025.0783 2.78 39978 25755 3 2025.07565 676.0334 X-ray repair cross-complementing protein 6 OS=Homo sapiens OX=9606 GN=XRCC6 PE=1 SV=2 4.56 3927.1 - 1.08E+06 - - - -1.2874 - 2.985 0.588 - 384.2 1 2 1 -0.0026 18 0 0 0 8.56E+06 3.08E+06 - - - 7.8181 0.9053 221125_WJC_METTL3_EV_vs_WT_F03.25759.25759.2 0.000204 16-Sep V.DAVIAELKK.Q "sp|P10809|CH60_HUMAN,tr|A0A7I2V2X6|A0A7I2V2X6_HUMAN,tr|A0A7I2V599|A0A7I2V599_HUMAN,tr|E7EXB4|E7EXB4_HUMAN,tr|A0A7I2YQ71|A0A7I2YQ71_HUMAN,tr|E7ESH4|E7ESH4_HUMAN,tr|A0A7I2V5M1|A0A7I2V5M1_HUMAN,tr|A0A7I2V5K3|A0A7I2V5K3_HUMAN,tr|A0A7I2V369|A0A7I2V369_HUMAN" 9 985.5808 1.18 39982 25759 2 985.577689 493.7977 "60 kDa heat shock protein, mitochondrial OS=Homo sapiens OX=9606 GN=HSPD1 PE=1 SV=2" 6.07 3927.7 - 306327 - - - -3.1535 - 2.016 0.317 - 386.3 1 1 0 -0.0031 9 0 0 0 1.65E+06 1.41E+06 - - - 3.4098 1 221125_WJC_METTL3_EV_vs_WT_F03.25763.25763.3 4.10E-13 25/100 R.MSLVEPQIPGISIPTDTSNMDLNGPK.K "sp|Q9Y2L1|RRP44_HUMAN,tr|G3V1J5|G3V1J5_HUMAN" 2 2753.3616 2.31 39984 25763 3 2753.357655 918.7945 Exosome complex exonuclease RRP44 OS=Homo sapiens OX=9606 GN=DIS3 PE=1 SV=2 4.03 3928.1 - 1.72E+06 - - - -1.4212 - 4.473 0.702 - 515.2 1 2 0 -0.0039 26 0 0 0 2.43E+07 1.05E+07 - - - 9.812 1 221125_WJC_METTL3_EV_vs_WT_F03.25764.25764.3 1.01E-08 19/68 R.K[136.11]EGGLGPLNIPLLADVTR[166.11].R "sp|P32119|PRDX2_HUMAN,tr|A6NIW5|A6NIW5_HUMAN" 2 1880.085 0.98 39985 25764 3 1880.085755 627.7023 Peroxiredoxin-2 OS=Homo sapiens OX=9606 GN=PRDX2 PE=1 SV=5 6.07 3928.3 - 796293 - - - 0.392 - 3.447 0.593 - 378 1 2 0 0.0007 18 0 0 0 4.05E+07 4.12E+07 - - - 8.2327 0.9999 221125_WJC_METTL3_EV_vs_WT_F03.25766.25766.2 5.87E-06 13/22 K.VDLLNQEIEFLK.V sp|P35908|K22E_HUMAN 1 1459.7922 999 39987 25766 2 1459.791207 730.9034 "Keratin, type II cytoskeletal 2 epidermal OS=Homo sapiens OX=9606 GN=KRT2 PE=1 SV=2" 4.14 3928.5 - 716842 - - - -0.7117 - 2.829 0.494 - 778.9 1 2 0 -0.001 12 0 0 0 1.00E+07 0.00E+00 - - - 5.4256 1 221125_WJC_METTL3_EV_vs_WT_F03.25772.25772.3 9.64E-14 22/104 K.VDEFPLC[160.03]GHMVSDEYEQLSSEALEAAR[166.11].L "sp|P27635|RL10_HUMAN,tr|A6QRI9|A6QRI9_HUMAN,tr|B8A6G2|B8A6G2_HUMAN,tr|X1WI28|X1WI28_HUMAN" 4 3091.3778 1.24 39991 25772 3 3091.373737 1031.4666 60S ribosomal protein L10 OS=Homo sapiens OX=9606 GN=RPL10 PE=1 SV=4 4 3929.3 - 1.37E+06 - - - -1.3263 - 4.31 0.741 - 370.1 1 2 0 -0.0041 27 0 0 0 2.51E+07 2.02E+07 - - - 10.1614 1 221125_WJC_METTL3_EV_vs_WT_F03.25773.25773.3 1.62E-09 18/68 R.KEGGLGPLNIPLLADVTR.R "sp|P32119|PRDX2_HUMAN,tr|A6NIW5|A6NIW5_HUMAN" 2 1862.0625 0.98 39992 25773 3 1862.068662 621.6948 Peroxiredoxin-2 OS=Homo sapiens OX=9606 GN=PRDX2 PE=1 SV=5 6.07 3929.4 - 1.42E+06 - - - 3.2835 - 3.334 0.611 - 354.4 1 2 0 0.0061 18 0 0 0 4.05E+07 4.12E+07 - - - 8.3489 1 221125_WJC_METTL3_EV_vs_WT_F03.25775.25775.3 1.03E-10 16/68 K.MEEDGSTVLGLLESSAEK.A "sp|O75410|TACC1_HUMAN,tr|E7EVI4|E7EVI4_HUMAN,tr|B4E3H6|B4E3H6_HUMAN,tr|E5RFM9|E5RFM9_HUMAN,tr|R4GMT7|R4GMT7_HUMAN,tr|H0YAY0|H0YAY0_HUMAN,tr|H0YBT8|H0YBT8_HUMAN,tr|E7ET87|E7ET87_HUMAN" 8 1893.8877 0.92 39994 25775 3 1893.888258 632.3032 Transforming acidic coiled-coil-containing protein 1 OS=Homo sapiens OX=9606 GN=TACC1 PE=1 SV=2 3.91 3929.7 - 747312 - - - 0.274 - 3.087 0.602 - 377.9 1 2 0 0.0005 18 0 0 0 3.20E+06 3.46E+06 - - - 8.0584 1 221125_WJC_METTL3_EV_vs_WT_F03.25776.25776.4 3.93E-08 19/126 K.GDNVYEFHLEFLDLVKPEPVYK.L "sp|Q9P035|HACD3_HUMAN,tr|H3BPZ1|H3BPZ1_HUMAN,tr|H3BS72|H3BS72_HUMAN" 3 2650.3319 1.03 39995 25776 4 2650.336147 663.5903 Very-long-chain (3R)-3-hydroxyacyl-CoA dehydratase 3 OS=Homo sapiens OX=9606 GN=HACD3 PE=1 SV=2 4.5 3929.8 - 626676 - - - 1.6002 - 2.932 0.558 - 193.6 1 2 0 0.0042 22 0 0 0 2.69E+06 2.61E+06 - - - 4.4336 0.995 221125_WJC_METTL3_EV_vs_WT_F03.25781.25781.3 0.00519 Aug-52 K.SK[136.11]INVNEIFYDLVR[166.11].Q "sp|A6NIZ1|RP1BL_HUMAN,sp|P62834|RAP1A_HUMAN,sp|P61224|RAP1B_HUMAN,tr|B7ZB78|B7ZB78_HUMAN,tr|F5GZG1|F5GZG1_HUMAN,tr|F5H823|F5H823_HUMAN" 6 1726.9373 0.96 40000 25781 3 1726.938359 576.653 Ras-related protein Rap-1b-like protein OS=Homo sapiens OX=9606 PE=2 SV=1 5.79 3930.5 - 271276 - - - 0.6184 - 1.552 0.317 - 73.2 1 2 1 0.0011 14 0 0 0 3.09E+06 3.23E+06 - - - 3.242 1 221125_WJC_METTL3_EV_vs_WT_F03.25786.25786.3 1.66E-11 23/84 R.IEELENLLQQGGSGVIETDLSK.L "sp|Q15643|TRIPB_HUMAN,tr|H0YJ97|H0YJ97_HUMAN" 2 2371.2119 1.39 40002 25786 3 2371.215053 791.4112 Thyroid receptor-interacting protein 11 OS=Homo sapiens OX=9606 GN=TRIP11 PE=1 SV=3 3.91 3931.2 - 3.30E+06 - - - 1.3504 - 3.971 0.636 - 712.2 1 2 0 0.0032 22 0 0 0 2.43E+07 1.75E+07 - - - 8.8993 1 221125_WJC_METTL3_EV_vs_WT_F03.25788.25788.3 2.06E-08 24/84 R.IEELENLLQQGGSGVIETDLSK[136.11].L "sp|Q15643|TRIPB_HUMAN,tr|H0YJ97|H0YJ97_HUMAN" 2 2379.2261 1.39 40004 25788 3 2379.225701 794.0826 Thyroid receptor-interacting protein 11 OS=Homo sapiens OX=9606 GN=TRIP11 PE=1 SV=3 3.91 3931.4 - 3.24E+06 - - - -0.1471 - 3.907 0.528 - 769.1 1 2 0 -0.0003 22 0 0 0 2.43E+07 1.75E+07 - - - 7.6575 1 221125_WJC_METTL3_EV_vs_WT_F03.25789.25789.3 6.38E-14 18/92 R.SQMESMLISGYALNC[160.03]VVGSQGMPK[136.11].R "sp|P17987|TCPA_HUMAN,tr|E7EQR6|E7EQR6_HUMAN,tr|E7ERF2|E7ERF2_HUMAN" 3 2594.2092 0.31 40005 25789 3 2594.20938 865.7437 T-complex protein 1 subunit alpha OS=Homo sapiens OX=9606 GN=TCP1 PE=1 SV=1 5.72 3931.5 - 2.05E+06 - - - 0.0551 - 3.849 0.654 - 223.3 1 2 0 0.0001 24 0 0 0 3.02E+06 9.62E+06 - - - 8.9618 1 221125_WJC_METTL3_EV_vs_WT_F03.25791.25791.3 1.96E-08 15/60 R.NVQALEIELQSQLALK.Q "sp|P13645|K1C10_HUMAN,tr|A0A1B0GVI3|A0A1B0GVI3_HUMAN" 2 1796.0044 5.92 40007 25791 3 1796.005548 599.6754 "Keratin, type I cytoskeletal 10 OS=Homo sapiens OX=9606 GN=KRT10 PE=1 SV=6" 4.53 3931.7 - 1.24E+06 - - - 0.6592 - 3.224 0.565 - 378 1 2 0 0.0012 16 0 0 0 7.18E+06 1.21E+06 - - - 7.8425 1 221125_WJC_METTL3_EV_vs_WT_F03.25792.25792.3 9.32E-10 17/68 K.EKAPSIIFIDELDAIGTK.R "sp|P17980|PRS6A_HUMAN,tr|R4GNH3|R4GNH3_HUMAN,tr|E9PMD8|E9PMD8_HUMAN,tr|E9PKD5|E9PKD5_HUMAN,tr|E9PM69|E9PM69_HUMAN,tr|E9PN50|E9PN50_HUMAN" 6 1959.0565 0.73 40008 25792 3 1959.056986 654.0261 26S proteasome regulatory subunit 6A OS=Homo sapiens OX=9606 GN=PSMC3 PE=1 SV=3 4.32 3931.8 - 1.10E+06 - - - 0.269 - 3.333 0.59 - 456.2 1 2 1 0.0005 18 0 0 0 8.80E+06 1.20E+07 - - - 8.1155 1 221125_WJC_METTL3_EV_vs_WT_F03.25793.25793.3 3.53E-10 27/72 R.INAGMLAQFIDKPVC[160.03]FVGR.L sp|P35244|RFA3_HUMAN 1 2135.102 2.07 40009 25793 3 2135.104714 712.7079 Replication protein A 14 kDa subunit OS=Homo sapiens OX=9606 GN=RPA3 PE=1 SV=1 8.22 3932 - 845294 - - - 1.2772 - 4.243 0.604 - 1017.3 1 2 0 0.0027 19 0 0 0 5.58E+06 2.70E+06 - - - 8.824 1 221125_WJC_METTL3_EV_vs_WT_F03.25795.25795.2 1.71E-12 17/32 K.MSSTFIGNSTAIQELFK.R "sp|Q13509|TBB3_HUMAN,tr|A0A0B4J269|A0A0B4J269_HUMAN" 2 1872.9291 1.07 40011 25795 2 1872.945511 937.4719 Tubulin beta-3 chain OS=Homo sapiens OX=9606 GN=TUBB3 PE=1 SV=2 5.75 3932.2 - 612571 - - - 8.7355 - 3.578 0.697 - 870.2 1 2 0 0.0164 17 0 0 0 1.28E+07 1.19E+07 - - - 7.3181 1 221125_WJC_METTL3_EV_vs_WT_F03.25796.25796.2 2.08E-13 15/32 K.MSSTFIGNSTAIQELFK[136.11].R "sp|Q13509|TBB3_HUMAN,tr|A0A0B4J269|A0A0B4J269_HUMAN" 2 1880.9434 1.1 40012 25796 2 1880.943077 941.479 Tubulin beta-3 chain OS=Homo sapiens OX=9606 GN=TUBB3 PE=1 SV=2 5.75 3932.4 - 524926 - - - -0.1451 - 2.929 0.673 - 632.3 1 2 0 -0.0003 17 0 0 0 1.31E+07 1.19E+07 - - - 6.6538 1 221125_WJC_METTL3_EV_vs_WT_F03.25807.25807.3 2.78E-06 18/56 R.EFESVLVDAFSHVAR.E sp|Q9NQG5|RPR1B_HUMAN 1 1704.8471 2.19 40021 25807 3 1704.848465 569.2897 Regulation of nuclear pre-mRNA domain-containing protein 1B OS=Homo sapiens OX=9606 GN=RPRD1B PE=1 SV=1 4.65 3933.8 - 2.02E+06 - - - 0.7801 - 3.225 0.569 - 597.4 1 2 0 0.0013 15 0 0 0 9.59E+06 4.37E+06 - - - 7.9388 0.9999 221125_WJC_METTL3_EV_vs_WT_F03.25808.25808.3 4.90E-10 17/68 K.EK[136.11]APSIIFIDELDAIGTK[136.11].R "sp|P17980|PRS6A_HUMAN,tr|R4GNH3|R4GNH3_HUMAN,tr|E9PMD8|E9PMD8_HUMAN,tr|E9PKD5|E9PKD5_HUMAN,tr|E9PM69|E9PM69_HUMAN,tr|E9PN50|E9PN50_HUMAN" 6 1975.0849 0.73 40022 25808 3 1975.08717 659.3689 26S proteasome regulatory subunit 6A OS=Homo sapiens OX=9606 GN=PSMC3 PE=1 SV=3 4.32 3933.8 - 2.35E+06 - - - 1.1701 - 3.38 0.618 - 414.6 1 2 1 0.0023 18 0 0 0 8.80E+06 1.20E+07 - - - 8.4621 1 221125_WJC_METTL3_EV_vs_WT_F03.25810.25810.3 8.81E-13 17/76 K.WSTDDVQINDISLQDYIAVK[136.11].E "sp|P46782|RS5_HUMAN,tr|M0R0F0|M0R0F0_HUMAN" 2 2330.1522 1.02 40024 25810 3 2330.157044 777.7247 40S ribosomal protein S5 OS=Homo sapiens OX=9606 GN=RPS5 PE=1 SV=4 3.77 3934 - 1.59E+06 - - - 2.0973 - 3.592 0.603 - 313 1 2 0 0.0049 20 0 0 0 2.74E+07 2.67E+07 - - - 8.3637 1 221125_WJC_METTL3_EV_vs_WT_F03.25811.25811.3 1.95E-14 25/80 K.WGDAGAEYVVESTGVFTTMEK.A "sp|P04406|G3P_HUMAN,tr|E7EUT5|E7EUT5_HUMAN" 2 2276.0307 0.91 40025 25811 3 2276.034292 759.6842 Glyceraldehyde-3-phosphate dehydrogenase OS=Homo sapiens OX=9606 GN=GAPDH PE=1 SV=3 4 3934.2 - 1.37E+06 - - - 1.5716 - 4.124 0.697 - 959.4 1 2 0 0.0036 21 0 0 0 1.74E+07 1.92E+07 - - - 9.7066 1 221125_WJC_METTL3_EV_vs_WT_F03.25813.25813.3 7.31E-08 20/56 R.EFESVLVDAFSHVAR[166.11].E sp|Q9NQG5|RPR1B_HUMAN 1 1714.8554 2.39 40027 25813 3 1714.856886 572.6257 Regulation of nuclear pre-mRNA domain-containing protein 1B OS=Homo sapiens OX=9606 GN=RPRD1B PE=1 SV=1 4.65 3934.4 - 822352 - - - 0.8636 - 3.182 0.502 - 702 1 2 0 0.0015 15 0 0 0 9.59E+06 4.02E+06 - - - 7.1568 1 221125_WJC_METTL3_EV_vs_WT_F03.25815.25815.3 7.05E-08 16/64 K.HQTLVLTLPTVAFLEDK.L "sp|Q9BYD3|RM04_HUMAN,tr|K7ES61|K7ES61_HUMAN" 2 1924.067 1.11 40029 25815 3 1924.069413 642.3629 "39S ribosomal protein L4, mitochondrial OS=Homo sapiens OX=9606 GN=MRPL4 PE=1 SV=1" 5.32 3934.7 - 519070 - - - 1.2728 - 3.375 0.526 - 410.7 1 2 0 0.0024 17 0 0 0 2.22E+06 2.00E+06 - - - 7.4767 0.9999 221125_WJC_METTL3_EV_vs_WT_F03.25816.25816.3 8.09E-05 13/64 K.ELQNTVSQLLESEGWNR[166.11].R "sp|Q7L0Y3|TM10C_HUMAN,tr|C9JVB6|C9JVB6_HUMAN" 2 2011.9839 0.87 40030 25816 3 2011.984587 671.6686 tRNA methyltransferase 10 homolog C OS=Homo sapiens OX=9606 GN=TRMT10C PE=1 SV=2 4.25 3934.8 - 460032 - - - 0.3648 - 2.411 0.385 - 235.9 1 2 0 0.0007 17 0 0 0 1.07E+06 1.24E+06 - - - 5.0554 0.9998 221125_WJC_METTL3_EV_vs_WT_F03.25817.25817.2 8.68E-06 30-Dec R.NVQALEIELQSQLALK.Q "sp|P13645|K1C10_HUMAN,tr|A0A1B0GVI3|A0A1B0GVI3_HUMAN" 2 1796.0044 999 40031 25817 2 1796.007096 899.0095 "Keratin, type I cytoskeletal 10 OS=Homo sapiens OX=9606 GN=KRT10 PE=1 SV=6" 4.53 3934.9 - 436493 - - - 1.5212 - 2.799 0.491 - 489.1 1 2 0 0.0027 16 0 0 0 1.53E+06 0.00E+00 - - - 5.1972 1 221125_WJC_METTL3_EV_vs_WT_F03.25818.25818.2 2.62E-14 24/38 K.WSTDDVQINDISLQDYIAVK[136.11].E "sp|P46782|RS5_HUMAN,tr|M0R0F0|M0R0F0_HUMAN" 2 2330.1522 1.07 40032 25818 2 2330.155165 1166.0834 40S ribosomal protein S5 OS=Homo sapiens OX=9606 GN=RPS5 PE=1 SV=4 3.77 3935.1 - 424082 - - - 1.2909 - 4.7 0.713 - 2101.2 1 2 0 0.003 20 0 0 0 1.15E+07 1.07E+07 - - - 8.111 1 221125_WJC_METTL3_EV_vs_WT_F03.25819.25819.2 1.71E-14 19/38 K.WSTDDVQINDISLQDYIAVK.E "sp|P46782|RS5_HUMAN,tr|M0R0F0|M0R0F0_HUMAN" 2 2322.138 1.07 40033 25819 2 2322.143946 1162.0763 40S ribosomal protein S5 OS=Homo sapiens OX=9606 GN=RPS5 PE=1 SV=4 3.77 3935.2 - 377556 - - - 2.5791 - 4.408 0.716 - 1044.8 1 2 0 0.006 20 0 0 0 1.15E+07 1.07E+07 - - - 7.9746 0.9992 221125_WJC_METTL3_EV_vs_WT_F03.25822.25822.3 0.0013 7/140 K.GSITSVQAIYVPADDLTDPAPATTFAHLDATTVLSR[166.11].A "sp|P06576|ATPB_HUMAN,tr|H0YI37|H0YI37_HUMAN,tr|H0YH81|H0YH81_HUMAN" 3 3723.8871 -1 40036 25822 3 3723.89451 1242.303 "ATP synthase subunit beta, mitochondrial OS=Homo sapiens OX=9606 GN=ATP5F1B PE=1 SV=3" 4.13 3935.6 - 213134 - - - 1.9882 - 1.79 0.364 - 18 1 2 0 0.0074 36 0 0 0 0.00E+00 0.00E+00 - - - 3.9357 0.9996 221125_WJC_METTL3_EV_vs_WT_F03.25823.25823.4 0.0445 7/102 R.VR[166.11]IPAEVLILNSIVLPHK[136.11].E "sp|Q96IJ6|GMPPA_HUMAN,tr|A0A804HIS0|A0A804HIS0_HUMAN" 2 2028.2578 0.87 40037 25823 4 2028.25985 508.0717 Mannose-1-phosphate guanyltransferase alpha OS=Homo sapiens OX=9606 GN=GMPPA PE=1 SV=1 8.73 3935.7 - 123437 - - - 0.9925 - 1.514 0.433 - 30.5 1 2 1 0.002 18 0 0 0 9.01E+05 1.04E+06 - - - 3.1364 1 221125_WJC_METTL3_EV_vs_WT_F03.25825.25825.3 6.52E-12 18/76 K.WSTDDVQINDISLQDYIAVK.E "sp|P46782|RS5_HUMAN,tr|M0R0F0|M0R0F0_HUMAN" 2 2322.138 1.02 40038 25825 3 2322.140015 775.0533 40S ribosomal protein S5 OS=Homo sapiens OX=9606 GN=RPS5 PE=1 SV=4 3.77 3936 - 7.99E+06 - - - 0.8863 - 3.557 0.665 - 417.9 1 2 0 0.0021 20 0 0 0 2.74E+07 2.67E+07 - - - 9.0319 1 221125_WJC_METTL3_EV_vs_WT_F03.25827.25827.3 1.09E-16 36/108 R.C[160.03]PEALFQPSFLGMESC[160.03]GIHETTFNSIMK.C "sp|P63261|ACTG_HUMAN,sp|P60709|ACTB_HUMAN,tr|A0A804GS07|A0A804GS07_HUMAN,tr|E7EVS6|E7EVS6_HUMAN,tr|A0A6Q8PFE4|A0A6Q8PFE4_HUMAN,tr|A0A2R8Y793|A0A2R8Y793_HUMAN,tr|I3L4N8|I3L4N8_HUMAN" 7 3230.4545 2.53 40039 25827 3 3230.451097 1077.8254 "Actin, cytoplasmic 2 OS=Homo sapiens OX=9606 GN=ACTG1 PE=1 SV=1" 4.75 3936.2 - 2.34E+06 - - - -1.0534 - 5.361 0.743 - 1259.4 1 2 0 -0.0034 28 0 0 0 1.05E+07 4.16E+06 - - - 10.6859 1 221125_WJC_METTL3_EV_vs_WT_F03.25828.25828.3 2.52E-09 17/64 R.RLEDLSESIVNDFAYMK.K sp|P49755|TMEDA_HUMAN 1 2028.9826 1.51 40040 25828 3 2028.983766 677.3348 Transmembrane emp24 domain-containing protein 10 OS=Homo sapiens OX=9606 GN=TMED10 PE=1 SV=2 4.32 3936.2 - 1.85E+06 - - - 0.554 - 3.565 0.637 - 449.4 1 2 0 0.0011 17 0 0 0 9.23E+06 6.11E+06 - - - 8.853 1 221125_WJC_METTL3_EV_vs_WT_F03.25829.25829.4 9.20E-13 35/210 K.IIPTLEEGLQLPSPTATSQLPLESDAVEC[160.03]LNYQHYK.G sp|P61978|HNRPK_HUMAN 1 4054.0245 1.23 40041 25829 4 4054.023033 1014.5134 Heterogeneous nuclear ribonucleoprotein K OS=Homo sapiens OX=9606 GN=HNRNPK PE=1 SV=1 4.25 3936.4 - 3.18E+06 - - - -0.3656 - 5.264 0.64 - 573.2 1 2 0 -0.0015 36 0 0 0 2.75E+07 2.24E+07 - - - 5.2857 1 221125_WJC_METTL3_EV_vs_WT_F03.25831.25831.3 1.57E-12 19/64 R.R[166.11]LEDLSESIVNDFAYMK[136.11].K sp|P49755|TMEDA_HUMAN 1 2047.0051 1.51 40043 25831 3 2046.998862 683.3423 Transmembrane emp24 domain-containing protein 10 OS=Homo sapiens OX=9606 GN=TMED10 PE=1 SV=2 4.32 3936.5 - 1.52E+06 - - - -3.0537 - 3.952 0.608 - 648.2 1 2 0 -0.0063 17 0 0 0 9.23E+06 6.11E+06 - - - 8.7886 0.9999 221125_WJC_METTL3_EV_vs_WT_F03.25835.25835.3 1.17E-07 13/52 K.VK[136.11]EEIIEAFVQELR[166.11].K sp|P50552|VASP_HUMAN 1 1719.9526 1.93 40047 25835 3 1719.951017 574.3248 Vasodilator-stimulated phosphoprotein OS=Homo sapiens OX=9606 GN=VASP PE=1 SV=3 4.49 3937 - 1.08E+06 - - - -0.9244 - 2.594 0.487 - 246.7 1 2 1 -0.0016 14 0 0 0 7.14E+06 3.71E+06 - - - 6.5023 1 221125_WJC_METTL3_EV_vs_WT_F03.25836.25836.2 1.74E-16 23/40 K.WGDAGAEYVVESTGVFTTMEK.A "sp|P04406|G3P_HUMAN,tr|E7EUT5|E7EUT5_HUMAN" 2 2276.0307 1.14 40048 25836 2 2276.033333 1139.0226 Glyceraldehyde-3-phosphate dehydrogenase OS=Homo sapiens OX=9606 GN=GAPDH PE=1 SV=3 4 3937.1 - 1.05E+06 - - - 1.1502 - 4.383 0.792 - 1753.6 1 2 0 0.0026 21 0 0 0 4.76E+06 4.19E+06 - - - 8.523 1 221125_WJC_METTL3_EV_vs_WT_F03.25837.25837.2 1.01E-12 18/36 K.QTQTPDLLPEALEAQVLPR.F "sp|Q9ULV3|CIZ1_HUMAN,tr|Q5SYW2|Q5SYW2_HUMAN,tr|F5H2X7|F5H2X7_HUMAN,tr|H0Y5D5|H0Y5D5_HUMAN,tr|A0A494C0L7|A0A494C0L7_HUMAN,tr|Q9BTG3|Q9BTG3_HUMAN" 6 2118.1321 3.62 40049 25837 2 2118.128098 1060.0733 Cip1-interacting zinc finger protein OS=Homo sapiens OX=9606 GN=CIZ1 PE=1 SV=2 4.14 3937.3 - 945463 - - - -1.8818 - 3.479 0.689 - 484.9 1 2 0 -0.004 19 0 0 0 1.17E+07 3.24E+06 - - - 7.1939 0.9999 221125_WJC_METTL3_EV_vs_WT_F03.25838.25838.3 5.06E-06 18/80 K.IREYFGEFGEIEAIELPMDPK.L "sp|Q99729|ROAA_HUMAN,tr|D6R9P3|D6R9P3_HUMAN,tr|D6RD18|D6RD18_HUMAN,tr|D6RBZ0|D6RBZ0_HUMAN" 4 2482.209 2.46 40050 25838 3 2482.209751 828.4103 Heterogeneous nuclear ribonucleoprotein A\B OS=Homo sapiens OX=9606 GN=HNRNPAB PE=1 SV=2 4.14 3937.4 - 934565 - - - 0.2969 - 3.363 0.523 - 329.7 1 2 1 0.0007 21 0 0 0 5.14E+06 2.09E+06 - - - 7.2784 0.9997 221125_WJC_METTL3_EV_vs_WT_F03.25839.25839.3 1.08E-08 15/80 K.IR[166.11]EYFGEFGEIEAIELPMDPK[136.11].L "sp|Q99729|ROAA_HUMAN,tr|D6R9P3|D6R9P3_HUMAN,tr|D6RD18|D6RD18_HUMAN,tr|D6RBZ0|D6RBZ0_HUMAN" 4 2500.2315 2.16 40051 25839 3 2500.224186 834.4178 Heterogeneous nuclear ribonucleoprotein A\B OS=Homo sapiens OX=9606 GN=HNRNPAB PE=1 SV=2 4.14 3937.5 - 910729 - - - -2.9189 - 3.153 0.545 - 204.9 1 2 1 -0.0073 21 0 0 0 4.51E+06 2.09E+06 - - - 7.3673 1 221125_WJC_METTL3_EV_vs_WT_F03.25841.25841.3 9.14E-10 24/68 P.R[166.11]VTEEDIVELFC[160.03]VC[160.03]GALK[136.11].R "sp|Q9BY77|PDIP3_HUMAN,tr|F6VRR5|F6VRR5_HUMAN" 2 2155.0772 0.96 40053 25841 3 2155.078192 719.3664 Polymerase delta-interacting protein 3 OS=Homo sapiens OX=9606 GN=POLDIP3 PE=1 SV=2 4.41 3937.8 - 392334 - - - 0.4455 - 4.247 0.623 - 814.2 1 1 0 0.001 18 0 0 0 4.44E+06 4.61E+06 - - - 9.0868 1 221125_WJC_METTL3_EV_vs_WT_F03.25845.25845.3 2.29E-12 19/76 R.IDTPSLEEPSDLEELEQFAK.T "sp|P14859|PO2F1_HUMAN,tr|A0A0C4DG88|A0A0C4DG88_HUMAN" 2 2289.09 2.16 40055 25845 3 2289.086491 764.0373 "POU domain, class 2, transcription factor 1 OS=Homo sapiens OX=9606 GN=POU2F1 PE=1 SV=2" 3.71 3938.3 - 3.56E+06 - - - -1.5347 - 3.607 0.645 - 552.2 1 2 0 -0.0035 20 0 0 0 9.38E+06 4.34E+06 - - - 8.8424 1 221125_WJC_METTL3_EV_vs_WT_F03.25847.25847.3 9.50E-09 23/72 K.QTQTPDLLPEALEAQVLPR[166.11].F "sp|Q9ULV3|CIZ1_HUMAN,tr|Q5SYW2|Q5SYW2_HUMAN,tr|F5H2X7|F5H2X7_HUMAN,tr|H0Y5D5|H0Y5D5_HUMAN,tr|A0A494C0L7|A0A494C0L7_HUMAN,tr|Q9BTG3|Q9BTG3_HUMAN" 6 2128.1404 1.89 40057 25847 3 2128.143322 710.3874 Cip1-interacting zinc finger protein OS=Homo sapiens OX=9606 GN=CIZ1 PE=1 SV=2 4.14 3938.5 - 3.68E+06 - - - 1.3946 - 3.635 0.582 - 784.4 1 2 0 0.003 19 0 0 0 5.47E+07 2.89E+07 - - - 8.1987 1 221125_WJC_METTL3_EV_vs_WT_F03.25850.25850.3 7.25E-07 23/68 P.RVTEEDIVELFC[160.03]VC[160.03]GALK.R "sp|Q9BY77|PDIP3_HUMAN,tr|F6VRR5|F6VRR5_HUMAN" 2 2137.0548 -1 40060 25850 3 2137.058285 713.3589 Polymerase delta-interacting protein 3 OS=Homo sapiens OX=9606 GN=POLDIP3 PE=1 SV=2 4.41 3938.9 - 1.48E+06 - - - 1.6485 - 4.337 0.599 - 777.5 1 1 0 0.0035 18 0 0 0 0.00E+00 0.00E+00 - - - 8.8707 0.9999 221125_WJC_METTL3_EV_vs_WT_F03.25853.25853.4 4.63E-14 30/162 K.LISPESTVMLLEAQAATGGIIDPHRNEK.L sp|P15924|DESP_HUMAN 1 2989.5543 20.47 40063 25853 4 2989.555761 748.3958 Desmoplakin OS=Homo sapiens OX=9606 GN=DSP PE=1 SV=3 4.83 3939.2 - 998207 - - - 0.4984 - 5.598 0.555 - 472.5 1 2 1 0.0015 28 0 0 0 4.07E+06 1.99E+05 - - - 4.5911 0.9999 221125_WJC_METTL3_EV_vs_WT_F03.25854.25854.3 4.31E-05 Dec-56 K.IEVPLYSLLEQTHLK[136.11].V "sp|Q92598|HS105_HUMAN,tr|A0A0A0MSM0|A0A0A0MSM0_HUMAN" 2 1790.0069 0.001 40064 25854 3 1790.005482 597.6763 Heat shock protein 105 kDa OS=Homo sapiens OX=9606 GN=HSPH1 PE=1 SV=1 5.4 3939.4 - 970464 - - - -0.8128 - 2.303 0.452 - 136.7 1 2 0 -0.0015 15 0 0 0 0.00E+00 4.57E+06 - - - 5.7557 1 221125_WJC_METTL3_EV_vs_WT_F03.25855.25855.2 3.64E-12 21/38 R.IDTPSLEEPSDLEELEQFAK.T "sp|P14859|PO2F1_HUMAN,tr|A0A0C4DG88|A0A0C4DG88_HUMAN" 2 2289.09 0.55 40065 25855 2 2289.092033 1145.5523 "POU domain, class 2, transcription factor 1 OS=Homo sapiens OX=9606 GN=POU2F1 PE=1 SV=2" 3.71 3939.5 - 922839 - - - 0.8864 - 4.311 0.722 - 1000.6 1 2 0 0.002 20 0 0 0 3.83E+06 6.95E+06 - - - 7.9654 1 221125_WJC_METTL3_EV_vs_WT_F03.25856.25856.3 6.88E-14 20/96 K.THYIVGYNLPSYEYLYNLGDQYALK[136.11].M "sp|P04843|RPN1_HUMAN,tr|B7Z4L4|B7Z4L4_HUMAN" 2 3004.4738 3.46 40066 25856 3 3004.469724 1002.4986 Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit 1 OS=Homo sapiens OX=9606 GN=RPN1 PE=1 SV=1 5.29 3939.6 - 850562 - - - -1.3653 - 4.016 0.591 - 426.1 1 2 0 -0.0041 25 0 0 0 1.66E+07 4.81E+06 - - - 8.3265 1 221125_WJC_METTL3_EV_vs_WT_F03.25857.25857.3 3.00E-08 21/64 K.FNHPEIVQLVSELEAER.S sp|Q7Z4H3|HDDC2_HUMAN 1 2009.0218 1.29 40067 25857 3 2009.024735 670.6812 5'-deoxynucleotidase HDDC2 OS=Homo sapiens OX=9606 GN=HDDC2 PE=1 SV=1 4.48 3939.8 - 646522 - - - 1.4584 - 3.844 0.602 - 598 1 2 0 0.0029 17 0 0 0 1.42E+07 1.10E+07 - - - 8.6526 0.9997 221125_WJC_METTL3_EV_vs_WT_F03.25860.25860.3 0.000326 Sep-68 R.SGAAQGLAEVMAGLGVEK.L sp|Q92616|GCN1_HUMAN 1 1686.8611 0.96 40070 25860 3 1686.861274 563.2943 eIF-2-alpha kinase activator GCN1 OS=Homo sapiens OX=9606 GN=GCN1 PE=1 SV=6 4.53 3940.2 - 475367 - - - 0.1203 - 1.6 0.406 - 89.3 1 2 0 0.0002 18 0 0 0 1.15E+06 1.20E+06 - - - 4.2368 0.9999 221125_WJC_METTL3_EV_vs_WT_F03.25861.25861.3 0.000613 Oct-68 R.SGAAQGLAEVMAGLGVEK[136.11].L sp|Q92616|GCN1_HUMAN 1 1694.8753 -1 40071 25861 3 1694.876501 565.9657 eIF-2-alpha kinase activator GCN1 OS=Homo sapiens OX=9606 GN=GCN1 PE=1 SV=6 4.53 3940.3 - 419169 - - - 0.7257 - 1.919 0.449 - 88.1 1 2 0 0.0012 18 0 0 0 0.00E+00 0.00E+00 - - - 5.1686 0.9967 221125_WJC_METTL3_EV_vs_WT_F03.25863.25863.4 0.000175 Sep-96 K.ELNAR[166.11]PLEVFMC[160.03]SVLK[136.11]R[166.11].Q "sp|Q9Y6B6|SAR1B_HUMAN,tr|D6R9R5|D6R9R5_HUMAN,tr|Q9H029|Q9H029_HUMAN" 3 2089.1171 0.65 40073 25863 4 2089.119855 523.2865 GTP-binding protein SAR1b OS=Homo sapiens OX=9606 GN=SAR1B PE=1 SV=1 8.32 3940.6 - 286453 - - - 1.3297 - 1.951 0.246 - 29.4 1 2 0 0.0028 17 0 0 0 9.63E+05 1.49E+06 - - - 1.5985 1 221125_WJC_METTL3_EV_vs_WT_F03.25866.25866.3 2.28E-12 25/72 K.QTQTPDLLPEALEAQVLPR.F "sp|Q9ULV3|CIZ1_HUMAN,tr|Q5SYW2|Q5SYW2_HUMAN,tr|F5H2X7|F5H2X7_HUMAN,tr|H0Y5D5|H0Y5D5_HUMAN,tr|A0A494C0L7|A0A494C0L7_HUMAN,tr|Q9BTG3|Q9BTG3_HUMAN" 6 2118.1321 1.9 40075 25866 3 2118.133906 707.0513 Cip1-interacting zinc finger protein OS=Homo sapiens OX=9606 GN=CIZ1 PE=1 SV=2 4.14 3941 - 9.59E+06 - - - 0.8602 - 3.763 0.638 - 992.2 1 2 0 0.0018 19 0 0 0 5.46E+07 2.87E+07 - - - 8.9084 1 221125_WJC_METTL3_EV_vs_WT_F03.25867.25867.3 8.22E-14 23/68 K.GHYTEGAELVDSVLDVVR[166.11].K "sp|Q9BVA1|TBB2B_HUMAN,sp|P07437|TBB5_HUMAN,sp|Q13509|TBB3_HUMAN,sp|Q13885|TBB2A_HUMAN,sp|P68371|TBB4B_HUMAN,tr|A0A0B4J269|A0A0B4J269_HUMAN,tr|Q5ST81|Q5ST81_HUMAN,tr|Q5JP53|Q5JP53_HUMAN,tr|G3V2A3|G3V2A3_HUMAN" 9 1967.9828 0.76 40076 25867 3 1967.980349 657.0015 Tubulin beta-2B chain OS=Homo sapiens OX=9606 GN=TUBB2B PE=1 SV=1 4.31 3941 - 1.46E+07 - - - -1.2409 - 4.172 0.719 - 836 1 2 0 -0.0024 18 0 0 0 8.43E+07 1.10E+08 - - - 10.1123 1 221125_WJC_METTL3_EV_vs_WT_F03.25868.25868.3 4.45E-12 22/68 K.GHYTEGAELVDSVLDVVR.K "sp|Q9BVA1|TBB2B_HUMAN,sp|P07437|TBB5_HUMAN,sp|Q13509|TBB3_HUMAN,sp|Q13885|TBB2A_HUMAN,sp|P68371|TBB4B_HUMAN,tr|A0A0B4J269|A0A0B4J269_HUMAN,tr|Q5ST81|Q5ST81_HUMAN,tr|Q5JP53|Q5JP53_HUMAN,tr|G3V2A3|G3V2A3_HUMAN" 9 1957.9745 0.76 40077 25868 3 1957.975364 653.6655 Tubulin beta-2B chain OS=Homo sapiens OX=9606 GN=TUBB2B PE=1 SV=1 4.31 3941 - 1.02E+07 - - - 0.4305 - 4.136 0.736 - 772.3 1 2 0 0.0008 18 0 0 0 8.43E+07 1.10E+08 - - - 10.2807 1 221125_WJC_METTL3_EV_vs_WT_F03.25870.25870.3 3.15E-15 34/116 K.ETGANLAIC[160.03]QWGFDDEANHLLLQNNLPAVR.W "sp|P48643|TCPE_HUMAN,tr|E9PCA1|E9PCA1_HUMAN,tr|B7ZAR1|B7ZAR1_HUMAN,tr|E7ENZ3|E7ENZ3_HUMAN" 4 3378.6415 0.76 40079 25870 3 3378.640356 1127.2211 T-complex protein 1 subunit epsilon OS=Homo sapiens OX=9606 GN=CCT5 PE=1 SV=1 4.31 3941.2 - 3.77E+06 - - - -0.3457 - 5.085 0.636 - 1210 1 2 0 -0.0012 30 0 0 0 1.03E+07 1.35E+07 - - - 9.372 1 221125_WJC_METTL3_EV_vs_WT_F03.25871.25871.3 1.12E-09 18/88 R.SLLVIPNTLAVNAAQDSTDLVAK[136.11].L "sp|P17987|TCPA_HUMAN,tr|F5H282|F5H282_HUMAN,tr|E7EQR6|E7EQR6_HUMAN" 3 2360.3042 0.48 40080 25871 3 2360.303291 787.7754 T-complex protein 1 subunit alpha OS=Homo sapiens OX=9606 GN=TCP1 PE=1 SV=1 4.21 3941.3 - 3.53E+06 - - - -0.4025 - 3.19 0.605 - 289.3 1 2 0 -0.001 23 0 0 0 3.33E+06 6.91E+06 - - - 8.0062 1 221125_WJC_METTL3_EV_vs_WT_F03.25874.25874.4 6.03E-08 25/174 K.ETGANLAIC[160.03]QWGFDDEANHLLLQNNLPAVR.W "sp|P48643|TCPE_HUMAN,tr|E9PCA1|E9PCA1_HUMAN,tr|B7ZAR1|B7ZAR1_HUMAN,tr|E7ENZ3|E7ENZ3_HUMAN" 4 3378.6415 -1 40083 25874 4 3378.642237 845.6677 T-complex protein 1 subunit epsilon OS=Homo sapiens OX=9606 GN=CCT5 PE=1 SV=1 4.31 3941.6 - 2.65E+06 - - - 0.211 - 3.785 0.594 - 238.2 1 2 0 0.0007 30 0 0 0 0.00E+00 0.00E+00 - - - 4.8033 1 221125_WJC_METTL3_EV_vs_WT_F03.25875.25875.3 6.11E-07 16/76 K.VISLQEC[160.03]LDEANAALDSASR[166.11].L "sp|Q15643|TRIPB_HUMAN,tr|H0YJI2|H0YJI2_HUMAN,tr|H0YJ97|H0YJ97_HUMAN" 3 2171.0404 0.51 40084 25875 3 2171.039753 724.6874 Thyroid receptor-interacting protein 11 OS=Homo sapiens OX=9606 GN=TRIP11 PE=1 SV=3 3.92 3941.7 - 2.55E+06 - - - -0.2897 - 3.242 0.455 - 361.9 1 2 0 -0.0006 20 0 0 0 4.44E+06 8.65E+06 - - - 6.4661 1 221125_WJC_METTL3_EV_vs_WT_F03.25876.25876.3 2.24E-13 21/76 K.VISLQEC[160.03]LDEANAALDSASR.L "sp|Q15643|TRIPB_HUMAN,tr|H0YJI2|H0YJI2_HUMAN,tr|H0YJ97|H0YJ97_HUMAN" 3 2161.0321 0.51 40085 25876 3 2161.032106 721.3513 Thyroid receptor-interacting protein 11 OS=Homo sapiens OX=9606 GN=TRIP11 PE=1 SV=3 3.92 3941.8 - 2.40E+06 - - - -0.0028 - 3.608 0.68 - 565.5 1 2 0 0 20 0 0 0 4.44E+06 8.65E+06 - - - 9.2343 1 221125_WJC_METTL3_EV_vs_WT_F03.25877.25877.3 1.79E-09 19/72 R.DLEK[136.11]PFLLPVEAVYSVPGR[166.11].G sp|P49411|EFTU_HUMAN 1 2146.1793 2.82 40086 25877 3 2146.179055 716.4004 "Elongation factor Tu, mitochondrial OS=Homo sapiens OX=9606 GN=TUFM PE=1 SV=2" 4.68 3941.9 - 1.82E+06 - - - -0.1197 - 3.634 0.612 - 391.7 1 2 0 -0.0003 19 0 0 0 2.27E+07 8.05E+06 - - - 8.5332 1 221125_WJC_METTL3_EV_vs_WT_F03.25878.25878.3 3.66E-14 23/92 K.TQAEIEQEMATLQYTNPQLLEQLK.L sp|Q9C0J8|WDR33_HUMAN 1 2818.4059 5.98 40087 25878 3 2818.406164 940.4759 pre-mRNA 3' end processing protein WDR33 OS=Homo sapiens OX=9606 GN=WDR33 PE=1 SV=2 4.09 3942 - 1.26E+06 - - - 0.1022 - 4.143 0.692 - 534.5 1 2 0 0.0003 24 0 0 0 8.74E+06 1.46E+06 - - - 9.5564 1 221125_WJC_METTL3_EV_vs_WT_F03.25879.25879.3 3.04E-08 19/140 K.IIPTLEEGLQLPSPTATSQLPLESDAVEC[160.03]LNYQHYK.G sp|P61978|HNRPK_HUMAN 1 4054.0245 -1 40088 25879 3 4054.026401 1352.3488 Heterogeneous nuclear ribonucleoprotein K OS=Homo sapiens OX=9606 GN=HNRNPK PE=1 SV=1 4.25 3942.2 - 946812 - - - 0.4652 - 3.393 0.628 - 184.1 1 2 0 0.0019 36 0 0 0 0.00E+00 0.00E+00 - - - 8.3518 1 221125_WJC_METTL3_EV_vs_WT_F03.25880.25880.3 5.75E-05 19/52 K.QGFDFLC[160.03]MPVFHPR.F "sp|O14744|ANM5_HUMAN,tr|C9JSX3|C9JSX3_HUMAN,tr|G3V580|G3V580_HUMAN,tr|G3V2L6|G3V2L6_HUMAN" 4 1749.812 3.2 40089 25880 3 1749.809545 584.2779 Protein arginine N-methyltransferase 5 OS=Homo sapiens OX=9606 GN=PRMT5 PE=1 SV=4 6.74 3942.3 - 895511 - - - -1.3761 - 2.676 0.56 - 368 1 2 0 -0.0024 14 0 0 0 1.11E+07 3.47E+06 - - - 7.3986 1 221125_WJC_METTL3_EV_vs_WT_F03.25882.25882.3 1.06E-07 13/140 K.IIPTLEEGLQLPSPTATSQLPLESDAVEC[160.03]LNYQHYK[136.11].G sp|P61978|HNRPK_HUMAN 1 4062.0387 1.69 40091 25882 3 4062.033824 1355.0202 Heterogeneous nuclear ribonucleoprotein K OS=Homo sapiens OX=9606 GN=HNRNPK PE=1 SV=1 4.25 3942.6 - 620884 - - - -1.2041 - 2.639 0.626 - 89.2 1 2 0 -0.0049 36 0 0 0 3.80E+06 2.25E+06 - - - 7.7505 1 221125_WJC_METTL3_EV_vs_WT_F03.25883.25883.3 4.07E-08 21/100 Y.YTGVPGLPSTFQYGPAVFPVAPTSSK[136.11].Q "sp|Q14157|UBP2L_HUMAN,tr|F8W726|F8W726_HUMAN,tr|H7C2T8|H7C2T8_HUMAN,tr|H0Y5H6|H0Y5H6_HUMAN" 4 2675.3727 2.7 40092 25883 3 2675.374599 892.7982 Ubiquitin-associated protein 2-like OS=Homo sapiens OX=9606 GN=UBAP2L PE=1 SV=2 8.5 3942.7 - 537811 - - - 0.7266 - 3.995 0.647 - 342.6 1 1 0 0.0019 26 0 0 0 1.64E+07 6.10E+06 - - - 8.9394 0.9995 221125_WJC_METTL3_EV_vs_WT_F03.25884.25884.2 0.0144 May-44 R.SLLVIPNTLAVNAAQDSTDLVAK[136.11].L "sp|P17987|TCPA_HUMAN,tr|F5H282|F5H282_HUMAN,tr|E7EQR6|E7EQR6_HUMAN" 3 2360.3042 -1 40093 25884 2 2360.30114 1181.1594 T-complex protein 1 subunit alpha OS=Homo sapiens OX=9606 GN=TCP1 PE=1 SV=1 4.21 3942.8 - 486378 - - - -1.3138 - 1.439 0.486 - 37.1 2 2 0 -0.0031 23 0 0 0 0.00E+00 0.00E+00 - - - 3.3899 0.9999 221125_WJC_METTL3_EV_vs_WT_F03.25885.25885.3 0.00846 16/40 R.LLASTLVHSVK[136.11].K "sp|Q9NYF8|BCLF1_HUMAN,tr|E9PKI6|E9PKI6_HUMAN,tr|A0A1W2PQ43|A0A1W2PQ43_HUMAN,tr|E9PK91|E9PK91_HUMAN,tr|E9PJA7|E9PJA7_HUMAN,tr|E9PK09|E9PK09_HUMAN,tr|E9PQN2|E9PQN2_HUMAN" 7 1174.7165 -1 40094 25885 3 1174.714644 392.5794 Bcl-2-associated transcription factor 1 OS=Homo sapiens OX=9606 GN=BCLAF1 PE=1 SV=2 8.76 3943 - 233187 - - - -1.5876 - 2.877 0.375 - 263.8 1 2 0 -0.0019 11 0 0 0 0.00E+00 0.00E+00 - - - 5.7224 1 221125_WJC_METTL3_EV_vs_WT_F03.25889.25889.3 4.24E-10 25/88 K.IMQSSSEVGYDAMAGDFVNMVEK.G "sp|P10809|CH60_HUMAN,tr|A0A7I2V2X6|A0A7I2V2X6_HUMAN,tr|A0A7I2YQK6|A0A7I2YQK6_HUMAN,tr|A0A7I2V599|A0A7I2V599_HUMAN" 4 2507.1018 1.27 40096 25889 3 2507.099831 836.7079 "60 kDa heat shock protein, mitochondrial OS=Homo sapiens OX=9606 GN=HSPD1 PE=1 SV=2" 3.92 3943.4 - 3.24E+07 - - - -0.8045 - 4.616 0.629 - 640.7 1 2 0 -0.002 23 0 0 0 1.81E+08 1.42E+08 - - - 9.1404 1 221125_WJC_METTL3_EV_vs_WT_F03.25890.25890.3 3.04E-14 23/100 Y.YTGVPGLPSTFQYGPAVFPVAPTSSK.Q "sp|Q14157|UBP2L_HUMAN,tr|F8W726|F8W726_HUMAN,tr|H7C2T8|H7C2T8_HUMAN,tr|H0Y5H6|H0Y5H6_HUMAN" 4 2667.3585 2.65 40097 25890 3 2667.359003 890.1268 Ubiquitin-associated protein 2-like OS=Homo sapiens OX=9606 GN=UBAP2L PE=1 SV=2 8.5 3943.5 - 4.14E+06 - - - 0.2054 - 4.012 0.682 - 412.7 1 1 0 0.0005 26 0 0 0 1.62E+07 6.10E+06 - - - 9.3397 1 221125_WJC_METTL3_EV_vs_WT_F03.25891.25891.2 4.13E-16 24/44 K.IMQSSSEVGYDAMAGDFVNMVEK.G "sp|P10809|CH60_HUMAN,tr|A0A7I2V2X6|A0A7I2V2X6_HUMAN,tr|A0A7I2YQK6|A0A7I2YQK6_HUMAN,tr|A0A7I2V599|A0A7I2V599_HUMAN" 4 2507.1018 1.14 40098 25891 2 2507.098379 1254.5582 "60 kDa heat shock protein, mitochondrial OS=Homo sapiens OX=9606 GN=HSPD1 PE=1 SV=2" 3.92 3943.5 - 3.53E+06 - - - -1.3837 - 4.732 0.755 - 1722.9 1 2 0 -0.0035 23 0 0 0 1.88E+07 1.64E+07 - - - 8.4378 0.9993 221125_WJC_METTL3_EV_vs_WT_F03.25893.25893.3 0.0098 Dec-40 R.LLASTLVHSVK.K "sp|Q9NYF8|BCLF1_HUMAN,tr|E9PKI6|E9PKI6_HUMAN,tr|A0A1W2PQ43|A0A1W2PQ43_HUMAN,tr|E9PK91|E9PK91_HUMAN,tr|E9PJA7|E9PJA7_HUMAN,tr|E9PK09|E9PK09_HUMAN,tr|E9PQN2|E9PQN2_HUMAN" 7 1166.7023 2.51 40100 25893 3 1166.699619 389.908 Bcl-2-associated transcription factor 1 OS=Homo sapiens OX=9606 GN=BCLAF1 PE=1 SV=2 8.76 3943.7 - 2.67E+06 - - - -2.3056 - 2.346 0.295 - 117.7 1 2 0 -0.0027 11 0 0 0 6.62E+06 2.63E+06 - - - 4.2506 1 221125_WJC_METTL3_EV_vs_WT_F03.25894.25894.3 6.71E-13 18/64 R.DQMQQQLNDYEQLLDVK.L "sp|P20700|LMNB1_HUMAN,tr|E9PBF6|E9PBF6_HUMAN" 2 2106.9892 1.12 40101 25894 3 2106.985321 703.337 Lamin-B1 OS=Homo sapiens OX=9606 GN=LMNB1 PE=1 SV=2 3.84 3943.7 - 2.38E+06 - - - -1.8334 - 3.734 0.729 - 462.3 1 2 0 -0.0039 17 0 0 0 7.68E+06 6.84E+06 - - - 9.9949 1 221125_WJC_METTL3_EV_vs_WT_F03.25896.25896.3 3.33E-05 20/64 K.FNHPEIVQLVSELEAER[166.11].S sp|Q7Z4H3|HDDC2_HUMAN 1 2019.0301 1.29 40103 25896 3 2019.027358 674.0173 5'-deoxynucleotidase HDDC2 OS=Homo sapiens OX=9606 GN=HDDC2 PE=1 SV=1 4.48 3944 - 1.21E+06 - - - -1.3457 - 3.426 0.474 - 527.9 1 2 0 -0.0027 17 0 0 0 1.42E+07 1.10E+07 - - - 6.9348 0.9999 221125_WJC_METTL3_EV_vs_WT_F03.25897.25897.3 5.55E-06 20/52 K.QGFDFLC[160.03]MPVFHPR[166.11].F "sp|O14744|ANM5_HUMAN,tr|C9JSX3|C9JSX3_HUMAN,tr|G3V580|G3V580_HUMAN,tr|G3V2L6|G3V2L6_HUMAN" 4 1759.8202 3.08 40104 25897 3 1759.816807 587.614 Protein arginine N-methyltransferase 5 OS=Homo sapiens OX=9606 GN=PRMT5 PE=1 SV=4 6.74 3944.1 - 1.19E+06 - - - -1.9411 - 2.903 0.438 - 542.2 1 2 0 -0.0034 14 0 0 0 1.07E+07 3.47E+06 - - - 6.2546 1 221125_WJC_METTL3_EV_vs_WT_F03.25898.25898.3 4.20E-14 21/104 K.HEEEAFTAFTPAPEDSLASVPYPPLLR.A "sp|P82930|RT34_HUMAN,tr|C9JJ19|C9JJ19_HUMAN" 2 2983.4604 2.63 40105 25898 3 2983.456876 995.4941 "28S ribosomal protein S34, mitochondrial OS=Homo sapiens OX=9606 GN=MRPS34 PE=1 SV=2" 4.25 3944.3 - 931853 - - - -1.1658 - 3.244 0.668 - 203.3 1 2 0 -0.0035 27 0 0 0 2.32E+07 8.81E+06 - - - 8.694 1 221125_WJC_METTL3_EV_vs_WT_F03.25900.25900.2 2.72E-15 16/32 R.DQMQQQLNDYEQLLDVK.L "sp|P20700|LMNB1_HUMAN,tr|E9PBF6|E9PBF6_HUMAN" 2 2106.9892 -1 40107 25900 2 2106.988195 1054.5019 Lamin-B1 OS=Homo sapiens OX=9606 GN=LMNB1 PE=1 SV=2 3.84 3944.5 - 697822 - - - -0.4694 - 3.937 0.734 - 696.4 1 2 0 -0.001 17 0 0 0 0.00E+00 0.00E+00 - - - 7.8313 0.9997 221125_WJC_METTL3_EV_vs_WT_F03.25901.25901.4 1.94E-06 20/156 R.LMNETTAVALAYGIYK[136.11]QDLPALEEK[136.11]PR[166.11].N "sp|P34932|HSP74_HUMAN,tr|A0A087WTS8|A0A087WTS8_HUMAN,tr|A0A087WYC1|A0A087WYC1_HUMAN" 3 3059.6212 0.7 40108 25901 4 3059.613364 765.9126 Heat shock 70 kDa protein 4 OS=Homo sapiens OX=9606 GN=HSPA4 PE=1 SV=4 4.87 3944.6 - 671585 - - - -2.5542 - 2.994 0.496 - 140 1 2 1 -0.0078 27 0 0 0 1.28E+06 1.84E+06 - - - 3.8841 1 221125_WJC_METTL3_EV_vs_WT_F03.25909.25909.3 3.86E-09 17/60 K.DFGNYLFNFASAATK[136.11]K[136.11].L sp|Q96A49|SYAP1_HUMAN 1 1808.9068 1.16 40114 25909 3 1808.902595 603.9762 Synapse-associated protein 1 OS=Homo sapiens OX=9606 GN=SYAP1 PE=1 SV=1 8.5 3945.6 - 7.32E+06 - - - -2.344 - 2.856 0.651 - 227.7 1 2 0 -0.0042 16 0 0 0 7.09E+07 6.14E+07 - - - 8.4895 1 221125_WJC_METTL3_EV_vs_WT_F03.25910.25910.3 2.03E-11 19/60 K.DFGNYLFNFASAATKK.L sp|Q96A49|SYAP1_HUMAN 1 1792.8784 1.16 40115 25910 3 1792.876357 598.6334 Synapse-associated protein 1 OS=Homo sapiens OX=9606 GN=SYAP1 PE=1 SV=1 8.5 3945.7 - 6.31E+06 - - - -1.159 - 3.492 0.679 - 304.5 1 2 0 -0.0021 16 0 0 0 7.09E+07 6.14E+07 - - - 9.3182 1 221125_WJC_METTL3_EV_vs_WT_F03.25911.25911.3 3.11E-10 23/112 K.MIGQATAADQEKNPEGDGLLEYSTFNFWR.A sp|Q13015|AF1Q_HUMAN 1 3287.5193 1.71 40116 25911 3 3287.515733 1096.8471 Protein AF1q OS=Homo sapiens OX=9606 GN=MLLT11 PE=1 SV=1 4.18 3945.8 - 2.77E+06 - - - -1.0978 - 4.442 0.647 - 420.7 1 2 1 -0.0036 29 0 0 0 9.53E+06 5.56E+06 - - - 9.1829 1 221125_WJC_METTL3_EV_vs_WT_F03.25912.25912.4 3.42E-06 18/132 R.TLTAVHDAILEDLVFPSEIVGKR.L "sp|P62081|RS7_HUMAN,tr|B5MCP9|B5MCP9_HUMAN,tr|A0A2R8Y623|A0A2R8Y623_HUMAN" 3 2522.3744 0.79 40117 25912 4 2522.371502 631.6009 40S ribosomal protein S7 OS=Homo sapiens OX=9606 GN=RPS7 PE=1 SV=1 4.75 3945.9 - 2.57E+06 - - - -1.1648 - 2.962 0.521 - 154.3 1 2 0 -0.0029 23 0 0 0 8.90E+06 1.13E+07 - - - 4.1118 1 221125_WJC_METTL3_EV_vs_WT_F03.25913.25913.2 6.66E-16 18/44 K.IMQSSSEVGYDAMAGDFVNMVEK[136.11].G "sp|P10809|CH60_HUMAN,tr|A0A7I2V2X6|A0A7I2V2X6_HUMAN,tr|A0A7I2YQK6|A0A7I2YQK6_HUMAN,tr|A0A7I2V599|A0A7I2V599_HUMAN" 4 2515.116 1.14 40118 25913 2 2515.110956 1258.5653 "60 kDa heat shock protein, mitochondrial OS=Homo sapiens OX=9606 GN=HSPD1 PE=1 SV=2" 3.92 3946 - 2.53E+06 - - - -2.0246 - 3.997 0.771 - 681.4 1 2 0 -0.0051 23 0 0 0 1.88E+07 1.64E+07 - - - 8.1404 1 221125_WJC_METTL3_EV_vs_WT_F03.25914.25914.3 1.37E-15 24/80 R.ANPDPNC[160.03]C[160.03]LGVFGLSLYTTER.D sp|P62995|TRA2B_HUMAN 1 2383.0937 2.25 40119 25914 3 2383.092584 795.3718 Transformer-2 protein homolog beta OS=Homo sapiens OX=9606 GN=TRA2B PE=1 SV=1 4.37 3946.1 - 2.46E+06 - - - -0.4545 - 3.913 0.71 - 565.2 1 2 0 -0.0011 21 0 0 0 1.54E+07 6.84E+06 - - - 9.7264 1 221125_WJC_METTL3_EV_vs_WT_F03.25916.25916.3 1.17E-08 17/80 R.ANPDPNC[160.03]C[160.03]LGVFGLSLYTTER[166.11].D sp|P62995|TRA2B_HUMAN 1 2393.1019 2.25 40121 25916 3 2393.101643 798.7079 Transformer-2 protein homolog beta OS=Homo sapiens OX=9606 GN=TRA2B PE=1 SV=1 4.37 3946.2 - 1.66E+06 - - - -0.1229 - 3.055 0.621 - 315.8 1 2 0 -0.0003 21 0 0 0 1.54E+07 6.84E+06 - - - 8.1409 1 221125_WJC_METTL3_EV_vs_WT_F03.25918.25918.3 6.93E-11 18/88 R.TLTAVHDAILEDLVFPSEIVGK[136.11]R[166.11].L "sp|P62081|RS7_HUMAN,tr|B5MCP9|B5MCP9_HUMAN,tr|A0A2R8Y623|A0A2R8Y623_HUMAN" 3 2540.3969 0.67 40123 25918 3 2540.393332 847.8062 40S ribosomal protein S7 OS=Homo sapiens OX=9606 GN=RPS7 PE=1 SV=1 4.75 3946.4 - 1.09E+06 - - - -1.4084 - 3.739 0.654 - 267.7 1 2 0 -0.0036 23 0 0 0 2.04E+06 3.05E+06 - - - 8.9243 1 221125_WJC_METTL3_EV_vs_WT_F03.25919.25919.3 1.12E-07 19/104 K.HEEEAFTAFTPAPEDSLASVPYPPLLR[166.11].A "sp|P82930|RT34_HUMAN,tr|C9JJ19|C9JJ19_HUMAN" 2 2993.4686 2.61 40124 25919 3 2993.470787 998.8302 "28S ribosomal protein S34, mitochondrial OS=Homo sapiens OX=9606 GN=MRPS34 PE=1 SV=2" 4.25 3946.6 - 514556 - - - 0.7226 - 2.244 0.547 - 97.9 1 2 0 0.0022 27 0 0 0 2.26E+07 8.66E+06 - - - 6.4974 1 221125_WJC_METTL3_EV_vs_WT_F03.25920.25920.3 2.43E-05 14/52 K.NSHLINVLMWELEK.K "sp|O15372|EIF3H_HUMAN,tr|B3KS98|B3KS98_HUMAN,tr|A0A087WZK9|A0A087WZK9_HUMAN,tr|E5RJT0|E5RJT0_HUMAN" 4 1724.892 -1 40125 25920 3 1724.88988 575.9713 Eukaryotic translation initiation factor 3 subunit H OS=Homo sapiens OX=9606 GN=EIF3H PE=1 SV=1 5.4 3946.7 - 476572 - - - -1.2157 - 2.971 0.494 - 377.5 1 2 0 -0.0021 14 0 0 0 0.00E+00 0.00E+00 - - - 6.9408 1 221125_WJC_METTL3_EV_vs_WT_F03.25921.25921.3 7.31E-06 Dec-52 K.NSHLINVLMWELEK[136.11].K "sp|O15372|EIF3H_HUMAN,tr|B3KS98|B3KS98_HUMAN,tr|A0A087WZK9|A0A087WZK9_HUMAN,tr|E5RJT0|E5RJT0_HUMAN" 4 1732.9062 -1 40126 25921 3 1732.90489 578.6427 Eukaryotic translation initiation factor 3 subunit H OS=Homo sapiens OX=9606 GN=EIF3H PE=1 SV=1 5.4 3946.8 - 340565 - - - -0.7427 - 2.617 0.505 - 222.4 1 2 0 -0.0013 14 0 0 0 0.00E+00 0.00E+00 - - - 6.7265 1 221125_WJC_METTL3_EV_vs_WT_F03.25929.25929.2 3.42E-18 17/30 K.DFGNYLFNFASAATKK.L sp|Q96A49|SYAP1_HUMAN 1 1792.8784 1.7 40132 25929 2 1792.875683 897.4465 Synapse-associated protein 1 OS=Homo sapiens OX=9606 GN=SYAP1 PE=1 SV=1 8.5 3947.6 - 3.01E+06 - - - -1.535 - 3.728 0.622 - 1034.2 1 2 0 -0.0028 16 0 0 0 1.12E+07 6.59E+06 - - - 6.8694 1 221125_WJC_METTL3_EV_vs_WT_F03.25932.25932.2 5.42E-18 16/30 K.DFGNYLFNFASAATK[136.11]K[136.11].L sp|Q96A49|SYAP1_HUMAN 1 1808.9068 1.7 40135 25932 2 1808.903225 905.4607 Synapse-associated protein 1 OS=Homo sapiens OX=9606 GN=SYAP1 PE=1 SV=1 8.5 3947.9 - 2.27E+06 - - - -1.9957 - 3.385 0.764 - 809.9 1 2 0 -0.0036 16 0 0 0 1.12E+07 6.59E+06 - - - 7.6806 1 221125_WJC_METTL3_EV_vs_WT_F03.25933.25933.3 5.56E-12 21/60 R.THNLEPYFESFINNLR.R sp|P04264|K2C1_HUMAN 1 1992.9694 3031.66 40136 25933 3 1992.965229 665.3304 "Keratin, type II cytoskeletal 1 OS=Homo sapiens OX=9606 GN=KRT1 PE=1 SV=6" 5.37 3948 - 2.05E+06 - - - -2.0808 - 4.04 0.614 - 813.7 1 2 0 -0.0041 16 0 0 0 4.37E+09 1.44E+06 - - - 8.9669 0.9995 221125_WJC_METTL3_EV_vs_WT_F03.25935.25935.3 3.76E-05 14/68 R.QATTIIADNIIFLSDQTK[136.11].E sp|Q04837|SSBP_HUMAN 1 1999.0717 0.98 40138 25935 3 1999.06469 667.3645 "Single-stranded DNA-binding protein, mitochondrial OS=Homo sapiens OX=9606 GN=SSBP1 PE=1 SV=1" 4.21 3948.2 - 1.38E+06 - - - -3.5176 - 2.821 0.367 - 251.7 1 2 0 -0.007 18 0 0 0 5.79E+06 5.93E+06 - - - 5.2122 1 221125_WJC_METTL3_EV_vs_WT_F03.25936.25936.3 6.93E-07 22/60 K.KLSGLNAFDIAEELVK.T "sp|O95983|MBD3_HUMAN,tr|A0A087X1H1|A0A087X1H1_HUMAN,tr|K7EIE8|K7EIE8_HUMAN,tr|A0A087WT34|A0A087WT34_HUMAN,tr|A0A0A0MTS6|A0A0A0MTS6_HUMAN" 5 1745.9564 1.33 40139 25936 3 1745.954627 582.9927 Methyl-CpG-binding domain protein 3 OS=Homo sapiens OX=9606 GN=MBD3 PE=1 SV=1 4.68 3948.3 - 1.23E+06 - - - -0.9874 - 3.633 0.507 - 971.6 1 2 0 -0.0017 16 0 0 0 1.91E+07 1.44E+07 - - - 7.5022 1 221125_WJC_METTL3_EV_vs_WT_F03.25937.25937.3 2.18E-10 21/60 K.K[136.11]LSGLNAFDIAEELVK[136.11].T "sp|O95983|MBD3_HUMAN,tr|A0A087X1H1|A0A087X1H1_HUMAN,tr|K7EIE8|K7EIE8_HUMAN,tr|A0A087WT34|A0A087WT34_HUMAN,tr|A0A0A0MTS6|A0A0A0MTS6_HUMAN" 5 1761.9848 1.35 40140 25937 3 1761.981585 588.3355 Methyl-CpG-binding domain protein 3 OS=Homo sapiens OX=9606 GN=MBD3 PE=1 SV=1 4.68 3948.5 - 962911 - - - -1.7968 - 3.572 0.569 - 893.7 1 2 0 -0.0032 16 0 0 0 1.91E+07 1.41E+07 - - - 8.1496 1 221125_WJC_METTL3_EV_vs_WT_F03.25946.25946.3 4.47E-07 18/68 R.ATSNVFAMFDQSQIQEFK[136.11].E "sp|O14950|ML12B_HUMAN,sp|P19105|ML12A_HUMAN,sp|P24844|MYL9_HUMAN,tr|J3KTJ1|J3KTJ1_HUMAN,tr|J3QRS3|J3QRS3_HUMAN" 5 2097.9921 -1 40147 25946 3 2097.987435 700.338 Myosin regulatory light chain 12B OS=Homo sapiens OX=9606 GN=MYL12B PE=1 SV=2 4.37 3949.6 - 6.63E+06 - - - -2.2193 - 3.427 0.581 - 489.1 1 2 0 -0.0047 18 0 0 0 0.00E+00 0.00E+00 - - - 8.0833 1 221125_WJC_METTL3_EV_vs_WT_F03.25947.25947.2 9.75E-13 17/34 R.ATSNVFAMFDQSQIQEFK[136.11].E "sp|O14950|ML12B_HUMAN,sp|P19105|ML12A_HUMAN,sp|P24844|MYL9_HUMAN,tr|J3KTJ1|J3KTJ1_HUMAN,tr|J3QRS3|J3QRS3_HUMAN" 5 2097.9921 -1 40148 25947 2 2097.984697 1050.0033 Myosin regulatory light chain 12B OS=Homo sapiens OX=9606 GN=MYL12B PE=1 SV=2 4.37 3949.7 - 3.07E+06 - - - -3.5243 - 4.011 0.689 - 1157.4 1 2 0 -0.0074 18 0 0 0 0.00E+00 0.00E+00 - - - 7.5427 1 221125_WJC_METTL3_EV_vs_WT_F03.25948.25948.3 2.94E-12 22/68 K.QDIVLTTYNILTHDYGTK[136.11].G "sp|Q14527|HLTF_HUMAN,tr|A0A0C4DGA6|A0A0C4DGA6_HUMAN" 2 2102.0775 1.15 40149 25948 3 2102.07605 701.6998 Helicase-like transcription factor OS=Homo sapiens OX=9606 GN=HLTF PE=1 SV=2 5.21 3949.8 - 5.60E+06 - - - -0.7069 - 4.029 0.513 - 798.2 1 2 0 -0.0015 18 0 0 0 1.56E+07 1.36E+07 - - - 7.729 1 221125_WJC_METTL3_EV_vs_WT_F03.25950.25950.3 8.75E-11 26/88 R.TVLGQQILGQLDSSSLALPSEAK.L sp|Q99959|PKP2_HUMAN 1 2354.2693 -1 40151 25950 3 2354.26913 785.7637 Plakophilin-2 OS=Homo sapiens OX=9606 GN=PKP2 PE=1 SV=2 4.37 3950 - 3.60E+06 - - - -0.0748 - 4.451 0.646 - 594.4 1 2 0 -0.0002 23 0 0 0 0.00E+00 0.00E+00 - - - 9.245 1 221125_WJC_METTL3_EV_vs_WT_F03.25953.25953.2 8.70E-16 16/34 R.ATSNVFAMFDQSQIQEFK.E "sp|O14950|ML12B_HUMAN,sp|P19105|ML12A_HUMAN,sp|P24844|MYL9_HUMAN,tr|J3KTJ1|J3KTJ1_HUMAN,tr|J3QRS3|J3QRS3_HUMAN" 5 2089.9779 -1 40154 25953 2 2089.973373 1045.9962 Myosin regulatory light chain 12B OS=Homo sapiens OX=9606 GN=MYL12B PE=1 SV=2 4.37 3950.3 - 2.77E+06 - - - -2.1617 - 3.835 0.688 - 1068.3 1 2 0 -0.0045 18 0 0 0 0.00E+00 0.00E+00 - - - 7.4259 1 221125_WJC_METTL3_EV_vs_WT_F03.25954.25954.2 6.68E-12 19/40 K.DDGVSIPGEYTSFLAPISSSK.L "sp|O14744|ANM5_HUMAN,tr|H0YJD3|H0YJD3_HUMAN,tr|H7BZ44|H7BZ44_HUMAN" 3 2169.0477 3.83 40155 25954 2 2169.041902 1085.5311 Protein arginine N-methyltransferase 5 OS=Homo sapiens OX=9606 GN=PRMT5 PE=1 SV=4 4.03 3950.4 - 2.68E+06 - - - -2.6938 - 3.269 0.695 - 779.4 1 2 0 -0.0058 21 0 0 0 3.78E+07 9.87E+06 - - - 7.0845 0.9999 221125_WJC_METTL3_EV_vs_WT_F03.25956.25956.3 0.026 13/52 K.KLSTDVDLIVEVLR.S sp|Q92615|LAR4B_HUMAN 1 1598.9243 -1 40157 25956 3 1598.921739 533.9821 La-related protein 4B OS=Homo sapiens OX=9606 GN=LARP4B PE=1 SV=3 4.56 3950.6 - 1.76E+06 - - - -1.6161 - 2.533 0.395 - 265.6 1 2 0 -0.0026 14 0 0 0 0.00E+00 0.00E+00 - - - 5.4131 0.9987 221125_WJC_METTL3_EV_vs_WT_F03.25957.25957.3 0.0161 13/52 K.K[136.11]LSTDVDLIVEVLR[166.11].S sp|Q92615|LAR4B_HUMAN 1 1616.9468 1.06 40158 25957 3 1616.943981 539.9895 La-related protein 4B OS=Homo sapiens OX=9606 GN=LARP4B PE=1 SV=3 4.56 3950.7 - 1.57E+06 - - - -1.7391 - 2.544 0.216 - 265.8 1 2 0 -0.0028 14 0 0 0 3.60E+06 3.38E+06 - - - 3.4288 1 221125_WJC_METTL3_EV_vs_WT_F03.25964.25964.3 3.43E-10 22/108 K.NIILEEGKEILVGDVGQTVDDPYATFVK.M "sp|P23528|COF1_HUMAN,tr|E9PP50|E9PP50_HUMAN,tr|G3V1A4|G3V1A4_HUMAN,tr|E9PQB7|E9PQB7_HUMAN,tr|E9PK25|E9PK25_HUMAN,tr|E9PLJ3|E9PLJ3_HUMAN,tr|E9PS23|E9PS23_HUMAN" 7 3061.5859 1.39 40163 25964 3 3061.584028 1021.5359 Cofilin-1 OS=Homo sapiens OX=9606 GN=CFL1 PE=1 SV=3 4.02 3951.7 - 1.16E+07 - - - -0.6275 - 4.746 0.658 - 437.8 1 2 1 -0.0019 28 0 0 0 6.99E+07 5.03E+07 - - - 9.4583 1 221125_WJC_METTL3_EV_vs_WT_F03.25965.25965.3 1.89E-06 25/104 R.GGGSVVIVSSIAAFSPSPGFSPYNVSK.T "sp|Q6PKH6|DR4L2_HUMAN,sp|Q9BTZ2|DHRS4_HUMAN,tr|A0A087WSZ6|A0A087WSZ6_HUMAN,tr|A0A087WXI8|A0A087WXI8_HUMAN,tr|H0YKN3|H0YKN3_HUMAN" 5 2610.333 1.81 40164 25965 3 2610.333365 871.1183 Dehydrogenase\reductase SDR family member 4-like 2 OS=Homo sapiens OX=9606 GN=DHRS4L2 PE=2 SV=2 8.59 3951.7 - 8.05E+06 - - - 0.1517 - 4.165 0.621 - 646.6 1 2 0 0.0004 27 0 0 0 3.52E+07 1.94E+07 - - - 8.7458 1 221125_WJC_METTL3_EV_vs_WT_F03.25967.25967.3 0.000217 16/76 K.LSDLQTQLSHEIQSDVLTIN.- sp|P19387|RPB3_HUMAN 1 2253.1489 - 40166 25967 3 2253.149825 752.0569 DNA-directed RNA polymerase II subunit RPB3 OS=Homo sapiens OX=9606 GN=POLR2C PE=1 SV=2 4.02 3951.8 - 3.15E+06 - - - 0.4301 - 3.91 0.443 - 302.6 1 2 0 0.001 20 0 0 0 - - - - - 6.7867 1 221125_WJC_METTL3_EV_vs_WT_F03.25968.25968.3 1.15E-10 25/92 R.ENISNAQALLEYHLSYLQEVEQLR[166.11].L sp|P51116|FXR2_HUMAN 1 2869.4486 -1 40167 25968 3 2869.448191 957.4901 Fragile X mental retardation syndrome-related protein 2 OS=Homo sapiens OX=9606 GN=FXR2 PE=1 SV=2 4.48 3952 - 1.74E+06 - - - -0.1276 - 5.018 0.617 - 627.6 1 2 0 -0.0004 24 0 0 0 0.00E+00 0.00E+00 - - - 9.1653 1 221125_WJC_METTL3_EV_vs_WT_F03.25969.25969.2 2.12E-11 18/40 K.DDGVSIPGEYTSFLAPISSSK[136.11].L "sp|O14744|ANM5_HUMAN,tr|H0YJD3|H0YJD3_HUMAN,tr|H7BZ44|H7BZ44_HUMAN" 3 2177.0619 3.83 40168 25969 2 2177.059565 1089.5382 Protein arginine N-methyltransferase 5 OS=Homo sapiens OX=9606 GN=PRMT5 PE=1 SV=4 4.03 3952.1 - 1.64E+06 - - - -1.0932 - 3.286 0.743 - 784.5 1 2 0 -0.0024 21 0 0 0 3.78E+07 9.87E+06 - - - 7.4529 1 221125_WJC_METTL3_EV_vs_WT_F03.25972.25972.3 4.79E-15 22/104 R.QQLVELVAEQADLEQTFNPSDPDC[160.03]VDR.L "sp|Q9BZZ5|API5_HUMAN,tr|H0YER7|H0YER7_HUMAN,tr|G3V1C3|G3V1C3_HUMAN" 3 3115.4404 -1 40171 25972 3 3115.435664 1039.4874 Apoptosis inhibitor 5 OS=Homo sapiens OX=9606 GN=API5 PE=1 SV=3 3.62 3952.5 - 1.25E+06 - - - -1.5279 - 4.036 0.681 - 330 1 2 0 -0.0048 27 0 0 0 0.00E+00 0.00E+00 - - - 9.3411 0.9951 221125_WJC_METTL3_EV_vs_WT_F03.25973.25973.3 1.22E-06 16/76 S.LTPPQLATPNLQQFFPQATR.Q "sp|Q9ULV3|CIZ1_HUMAN,tr|Q5SYW2|Q5SYW2_HUMAN,tr|F5H2X7|F5H2X7_HUMAN,tr|H0Y5D5|H0Y5D5_HUMAN,tr|F6WSM2|F6WSM2_HUMAN,tr|A0A494C0L7|A0A494C0L7_HUMAN,tr|Q9BTG3|Q9BTG3_HUMAN,tr|F6VD24|F6VD24_HUMAN" 8 2267.2063 6.51 40172 25973 3 2267.205831 756.7427 Cip1-interacting zinc finger protein OS=Homo sapiens OX=9606 GN=CIZ1 PE=1 SV=2 9.75 3952.6 - 928729 - - - -0.1857 - 2.73 0.448 - 244.3 1 1 0 -0.0004 20 0 0 0 3.99E+06 6.12E+05 - - - 5.9711 0.9999 221125_WJC_METTL3_EV_vs_WT_F03.25976.25976.3 2.26E-09 16/124 K.VVSNLPAITMEEVAPVSVSDAALLAPEEIKEK.N sp|O00566|MPP10_HUMAN 1 3348.7738 -1 40175 25976 3 3348.780327 1117.2652 U3 small nucleolar ribonucleoprotein protein MPP10 OS=Homo sapiens OX=9606 GN=MPHOSPH10 PE=1 SV=2 4.14 3953 - 729821 - - - 1.9413 - 3.024 0.612 - 166.2 1 2 1 0.0065 32 0 0 0 0.00E+00 0.00E+00 - - - 7.9072 1 221125_WJC_METTL3_EV_vs_WT_F03.25985.25985.2 4.84E-08 17/30 R.THNLEPYFESFINNLR.R sp|P04264|K2C1_HUMAN 1 1992.9694 564.75 40182 25985 2 1992.967048 997.492 "Keratin, type II cytoskeletal 1 OS=Homo sapiens OX=9606 GN=KRT1 PE=1 SV=6" 5.37 3954.1 - 9.83E+06 - - - -1.1681 - 3.184 0.692 - 595.1 1 2 0 -0.0023 16 0 0 0 4.02E+08 7.13E+05 - - - 6.9987 1 221125_WJC_METTL3_EV_vs_WT_F03.25986.25986.3 3.41E-19 29/108 K.NIILEEGK[136.11]EILVGDVGQTVDDPYATFVK[136.11].M "sp|P23528|COF1_HUMAN,tr|E9PP50|E9PP50_HUMAN,tr|G3V1A4|G3V1A4_HUMAN,tr|E9PQB7|E9PQB7_HUMAN,tr|E9PK25|E9PK25_HUMAN,tr|E9PLJ3|E9PLJ3_HUMAN,tr|E9PS23|E9PS23_HUMAN" 7 3077.6143 1.39 40183 25986 3 3077.609414 1026.8787 Cofilin-1 OS=Homo sapiens OX=9606 GN=CFL1 PE=1 SV=3 4.02 3954.1 - 6.19E+06 - - - -1.6035 - 5.263 0.757 - 893.4 1 2 1 -0.0049 28 0 0 0 6.99E+07 5.03E+07 - - - 10.7991 1 221125_WJC_METTL3_EV_vs_WT_F03.25987.25987.3 8.67E-09 15/84 R.DSAAAVVVYDITNVNSFQQTTK.W "sp|Q9H0N0|RAB6C_HUMAN,sp|Q53S08|RAB6D_HUMAN" 2 2370.1703 1.09 40184 25987 3 2370.163298 791.064 Ras-related protein Rab-6C OS=Homo sapiens OX=9606 GN=RAB6C PE=1 SV=2 4.21 3954.2 - 5.58E+06 - - - -2.9627 - 3.49 0.631 - 230.7 1 2 0 -0.007 22 0 0 0 1.58E+07 1.46E+07 - - - 8.5364 1 221125_WJC_METTL3_EV_vs_WT_F03.25988.25988.4 1.22E-11 18/90 R.THNLEPYFESFINNLR.R sp|P04264|K2C1_HUMAN 1 1992.9694 999 40185 25988 4 1992.967097 499.2496 "Keratin, type II cytoskeletal 1 OS=Homo sapiens OX=9606 GN=KRT1 PE=1 SV=6" 5.37 3954.3 - 4.29E+06 - - - -1.1435 - 3.49 0.629 - 263.4 1 2 0 -0.0023 16 0 0 0 1.14E+08 0.00E+00 - - - 5.1405 1 221125_WJC_METTL3_EV_vs_WT_F03.25992.25992.2 4.34E-07 17/32 R.TTYQIENFAQAFGSQFK.S sp|Q9Y2X9|ZN281_HUMAN 1 1978.9425 -1 40189 25992 2 1978.939668 990.4785 Zinc finger protein 281 OS=Homo sapiens OX=9606 GN=ZNF281 PE=1 SV=1 5.66 3954.7 - 1.02E+06 - - - -1.427 - 3.075 0.681 - 896.3 1 2 0 -0.0028 17 0 0 0 0.00E+00 0.00E+00 - - - 6.8317 1 221125_WJC_METTL3_EV_vs_WT_F03.25994.25994.2 1.17E-10 15/32 R.TTYQIENFAQAFGSQFK[136.11].S sp|Q9Y2X9|ZN281_HUMAN 1 1986.9567 0.21 40191 25994 2 1986.95535 994.4856 Zinc finger protein 281 OS=Homo sapiens OX=9606 GN=ZNF281 PE=1 SV=1 5.66 3954.9 - 879362 - - - -0.6754 - 2.667 0.636 - 284.1 1 2 0 -0.0013 17 0 0 0 3.62E+06 1.70E+07 - - - 6.1498 0.9265 221125_WJC_METTL3_EV_vs_WT_F03.25998.25998.2 0.0776 14-Aug M.FEYPEYQR.- tr|F8WD75|F8WD75_HUMAN 1 1130.5033 9.61 40195 25998 2 1130.503673 566.2589 GPI inositol-deacylase OS=Homo sapiens OX=9606 GN=PGAP1 PE=4 SV=1 4.53 3955.5 - 306987 - - - 0.3521 - 1.184 0.355 - 111.6 1 1 0 0.0004 8 0 0 0 9.77E+06 1.02E+06 - - - 2.1723 0.8062 221125_WJC_METTL3_EV_vs_WT_F03.25999.25999.2 0.0122 16-Oct Y.FESFINNLR.R sp|P04264|K2C1_HUMAN 1 1138.5771 1.13 40196 25999 2 1138.571207 570.2958 "Keratin, type II cytoskeletal 1 OS=Homo sapiens OX=9606 GN=KRT1 PE=1 SV=6" 6 3955.6 - 295394 - - - -5.1828 - 1.978 0.433 - 312.4 1 1 0 -0.0059 9 0 0 0 4.19E+06 3.72E+06 - - - 4.2106 1 221125_WJC_METTL3_EV_vs_WT_F03.26005.26005.4 3.03E-11 49/252 K.LLAAYPGASGLGSAAAAAAAAASC[160.03]HLHLPPPAAPGSPGSLSLR.N sp|Q9H7S9|ZN703_HUMAN 1 3947.0476 2.26 40200 26005 4 3947.038805 987.7692 Zinc finger protein 703 OS=Homo sapiens OX=9606 GN=ZNF703 PE=1 SV=1 8.24 3956.3 - 3.34E+06 - - - -2.2257 - 5.459 0.644 - 874.8 1 2 0 -0.0088 43 0 0 0 2.37E+07 1.05E+07 - - - 5.312 1 221125_WJC_METTL3_EV_vs_WT_F03.26006.26006.4 1.21E-14 34/162 K.QHNIFLDQMTIDEDKLIAQNLELNETIK.L "sp|P52732|KIF11_HUMAN,tr|A0A7I2V3A9|A0A7I2V3A9_HUMAN" 2 3325.6864 6.92 40201 26006 4 3325.678416 832.4289 Kinesin-like protein KIF11 OS=Homo sapiens OX=9606 GN=KIF11 PE=1 SV=2 4.29 3956.4 - 1.66E+06 - - - -2.4031 - 4.89 0.627 - 774.2 1 2 1 -0.008 28 0 0 0 5.15E+07 7.44E+06 - - - 5.174 0.9997 221125_WJC_METTL3_EV_vs_WT_F03.26009.26009.3 3.56E-09 18/80 K.DDGVSIPGEYTSFLAPISSSK.L "sp|O14744|ANM5_HUMAN,tr|H0YJD3|H0YJD3_HUMAN,tr|H7BZ44|H7BZ44_HUMAN" 3 2169.0477 4.78 40204 26009 3 2169.036574 724.0232 Protein arginine N-methyltransferase 5 OS=Homo sapiens OX=9606 GN=PRMT5 PE=1 SV=4 4.03 3956.8 - 1.08E+06 - - - -5.1502 - 3.001 0.572 - 412 1 2 0 -0.0112 21 0 0 0 2.33E+07 4.86E+06 - - - 7.5488 0.9999 221125_WJC_METTL3_EV_vs_WT_F03.26010.26010.3 0.000197 Nov-68 K.VEPAVSSVVNSIQVLTSK.A "sp|Q9P2E9|RRBP1_HUMAN,tr|A2A2S5|A2A2S5_HUMAN" 2 1856.0255 1.13 40205 26010 3 1856.025719 619.6824 Ribosome-binding protein 1 OS=Homo sapiens OX=9606 GN=RRBP1 PE=1 SV=5 5.97 3956.9 - 743427 - - - 0.1212 - 2.642 0.384 - 147.7 1 2 0 0.0002 18 0 0 0 5.67E+06 5.03E+06 - - - 5.2404 0.9998 221125_WJC_METTL3_EV_vs_WT_F03.26018.26018.2 5.02E-06 20-Nov R.NPEAALSPTFR[166.11].S "sp|Q86U44|MTA70_HUMAN,tr|B4E349|B4E349_HUMAN,tr|F5H6D8|F5H6D8_HUMAN,tr|B4DTN4|B4DTN4_HUMAN" 4 1211.6174 0.001 40211 26018 2 1211.615873 606.816 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 6 3957.9 - 535524 - - - -1.2661 - 2.13 0.488 - 270.4 1 2 0 -0.0015 11 0 0 0 0.00E+00 4.86E+06 - - - 4.6904 1 221125_WJC_METTL3_EV_vs_WT_F03.26022.26022.3 2.40E-11 20/80 K.NQILNLTTDNANILLQIDNAR.L "sp|P13645|K1C10_HUMAN,tr|A0A1B0GVI3|A0A1B0GVI3_HUMAN" 2 2366.2554 809.59 40213 26022 3 2366.249757 789.7591 "Keratin, type I cytoskeletal 10 OS=Homo sapiens OX=9606 GN=KRT10 PE=1 SV=6" 4.21 3958.5 - 5.86E+06 - - - -2.3793 - 3.59 0.628 - 461.9 1 2 0 -0.0056 21 0 0 0 1.18E+09 1.46E+06 - - - 8.6043 1 221125_WJC_METTL3_EV_vs_WT_F03.26023.26023.2 2.07E-09 15/32 K.NATNVEQSFMTMAAEIK.K "sp|P62820|RAB1A_HUMAN,tr|E7END7|E7END7_HUMAN" 2 1883.8757 1.62 40214 26023 2 1883.874639 942.9451 Ras-related protein Rab-1A OS=Homo sapiens OX=9606 GN=RAB1A PE=1 SV=3 4.53 3958.6 - 1.99E+06 - - - -0.5818 - 3.287 0.601 - 749.1 1 2 0 -0.0011 17 0 0 0 1.79E+07 1.11E+07 - - - 6.4053 0.9999 221125_WJC_METTL3_EV_vs_WT_F03.26025.26025.3 4.23E-06 19/64 K.NATNVEQSFMTMAAEIK[136.11].K "sp|P62820|RAB1A_HUMAN,tr|E7END7|E7END7_HUMAN" 2 1891.8899 1.27 40216 26025 3 1891.884286 631.6373 Ras-related protein Rab-1A OS=Homo sapiens OX=9606 GN=RAB1A PE=1 SV=3 4.53 3958.7 - 2.96E+06 - - - -2.9859 - 3.124 0.551 - 343.4 1 2 0 -0.0056 17 0 0 0 2.28E+07 1.80E+07 - - - 7.5593 1 221125_WJC_METTL3_EV_vs_WT_F03.26027.26027.3 2.97E-08 19/76 R.K[136.11]LPIDVTEGEVISLGLPFGK[136.11].V "sp|P26599|PTBP1_HUMAN,tr|A0A6Q8PEX4|A0A6Q8PEX4_HUMAN,tr|A0A0U1RRM4|A0A0U1RRM4_HUMAN,tr|A6NLN1|A6NLN1_HUMAN,tr|K7EKJ7|K7EKJ7_HUMAN,tr|K7ELW5|K7ELW5_HUMAN,tr|K7ES59|K7ES59_HUMAN,tr|A0A7I2V4H6|A0A7I2V4H6_HUMAN,tr|A0A7I2V621|A0A7I2V621_HUMAN" 9 2127.2162 0.98 40218 26027 3 2127.211455 710.0793 Polypyrimidine tract-binding protein 1 OS=Homo sapiens OX=9606 GN=PTBP1 PE=1 SV=1 4.68 3958.9 - 848014 - - - -2.2344 - 2.857 0.594 - 317.6 1 2 0 -0.0048 20 0 0 0 4.18E+07 4.25E+07 - - - 7.708 1 221125_WJC_METTL3_EV_vs_WT_F03.26032.26032.2 6.45E-13 26/40 K.NQILNLTTDNANILLQIDNAR.L "sp|P13645|K1C10_HUMAN,tr|A0A1B0GVI3|A0A1B0GVI3_HUMAN" 2 2366.2554 999 40221 26032 2 2366.252301 1184.135 "Keratin, type I cytoskeletal 10 OS=Homo sapiens OX=9606 GN=KRT10 PE=1 SV=6" 4.21 3959.6 - 1.81E+06 - - - -1.3042 - 4.963 0.624 - 1854.4 1 2 0 -0.0031 21 0 0 0 1.44E+08 0.00E+00 - - - 7.5875 0.9999 221125_WJC_METTL3_EV_vs_WT_F03.26033.26033.3 0.0024 18/64 K.SVQNDSQAIAEVLNQLK.D sp|P15924|DESP_HUMAN 1 1855.964 40.24 40222 26033 3 1855.957386 619.6619 Desmoplakin OS=Homo sapiens OX=9606 GN=DSP PE=1 SV=3 4.37 3959.6 - 2.95E+06 - - - -3.5399 - 2.819 0.521 - 486.6 1 2 0 -0.0066 17 0 0 0 4.11E+07 1.02E+06 - - - 6.965 1 221125_WJC_METTL3_EV_vs_WT_F03.26034.26034.2 2.74E-12 17/42 R.DNYVPEVSALDQEIIEVDPDTK.E "sp|P08708|RS17_HUMAN,tr|H3BNC9|H3BNC9_HUMAN,tr|H0YN88|H0YN88_HUMAN,tr|A0A075B716|A0A075B716_HUMAN" 4 2488.1857 1.99 40223 26034 2 2488.180254 1245.1001 40S ribosomal protein S17 OS=Homo sapiens OX=9606 GN=RPS17 PE=1 SV=2 3.62 3959.8 - 1.66E+06 - - - -2.1867 - 3.353 0.718 - 354.3 1 2 0 -0.0054 22 0 0 0 1.12E+08 5.63E+07 - - - 7.3169 1 221125_WJC_METTL3_EV_vs_WT_F03.26035.26035.2 2.48E-07 16/32 K.NATNVEQSFMTMAAEIK[136.11].K "sp|P62820|RAB1A_HUMAN,tr|E7END7|E7END7_HUMAN" 2 1891.8899 1.62 40224 26035 2 1891.885328 946.9522 Ras-related protein Rab-1A OS=Homo sapiens OX=9606 GN=RAB1A PE=1 SV=3 4.53 3959.9 - 1.64E+06 - - - -2.4351 - 3.432 0.63 - 968.3 1 2 0 -0.0046 17 0 0 0 1.79E+07 1.11E+07 - - - 6.7245 1 221125_WJC_METTL3_EV_vs_WT_F03.26038.26038.2 8.92E-13 21/32 K.SVQNDSQAIAEVLNQLK.D sp|P15924|DESP_HUMAN 1 1855.964 19.88 40227 26038 2 1855.955845 928.9893 Desmoplakin OS=Homo sapiens OX=9606 GN=DSP PE=1 SV=3 4.37 3960.3 - 1.22E+06 - - - -4.3702 - 3.942 0.688 - 1604.1 1 2 0 -0.0081 17 0 0 0 2.00E+07 1.00E+06 - - - 7.4924 1 221125_WJC_METTL3_EV_vs_WT_F03.26039.26039.2 2.33E-09 15/42 R.DNYVPEVSALDQEIIEVDPDTK[136.11].E "sp|P08708|RS17_HUMAN,tr|H3BNC9|H3BNC9_HUMAN,tr|H0YN88|H0YN88_HUMAN,tr|A0A075B716|A0A075B716_HUMAN" 4 2496.1999 1.99 40228 26039 2 2498.205447 1249.1072 40S ribosomal protein S17 OS=Homo sapiens OX=9606 GN=RPS17 PE=1 SV=2 3.62 3960.4 - 1.10E+06 - - - 803.4421 - 3.066 0.683 - 293.1 1 2 0 2.0056 22 0 0 0 1.12E+08 5.63E+07 - - - 6.2104 0.9659 221125_WJC_METTL3_EV_vs_WT_F03.26040.26040.2 0.149 Jun-34 K.SNLAYDIVQLPTGLTGIK[136.11].V "sp|P34932|HSP74_HUMAN,tr|A0A087WTS8|A0A087WTS8_HUMAN,tr|A0A087WYC1|A0A087WYC1_HUMAN" 3 1910.0604 0.001 40229 26040 2 1910.054643 956.0375 Heat shock 70 kDa protein 4 OS=Homo sapiens OX=9606 GN=HSPA4 PE=1 SV=4 5.55 3960.6 - 0 - - - -3.0292 - 1.374 0.151 - 64.7 2 2 0 -0.0058 18 0 0 0 0.00E+00 3.45E+06 - - - 0.8011 1 221125_WJC_METTL3_EV_vs_WT_F03.26043.26043.3 1.84E-12 16/84 R.DNYVPEVSALDQEIIEVDPDTK.E "sp|P08708|RS17_HUMAN,tr|H3BNC9|H3BNC9_HUMAN,tr|H0YN88|H0YN88_HUMAN,tr|A0A075B716|A0A075B716_HUMAN" 4 2488.1857 1.49 40230 26043 3 2488.180722 830.4025 40S ribosomal protein S17 OS=Homo sapiens OX=9606 GN=RPS17 PE=1 SV=2 3.62 3961 - 1.93E+07 - - - -1.9986 - 3.138 0.663 - 157.1 1 2 0 -0.005 22 0 0 0 4.99E+08 3.36E+08 - - - 8.6417 1 221125_WJC_METTL3_EV_vs_WT_F03.26046.26046.3 6.64E-09 25/76 R.KLPIDVTEGEVISLGLPFGK.V "sp|P26599|PTBP1_HUMAN,tr|A0A6Q8PEX4|A0A6Q8PEX4_HUMAN,tr|A0A0U1RRM4|A0A0U1RRM4_HUMAN,tr|A6NLN1|A6NLN1_HUMAN,tr|K7EKJ7|K7EKJ7_HUMAN,tr|K7ELW5|K7ELW5_HUMAN,tr|K7ES59|K7ES59_HUMAN,tr|A0A7I2V4H6|A0A7I2V4H6_HUMAN,tr|A0A7I2V621|A0A7I2V621_HUMAN" 9 2111.1878 0.98 40233 26046 3 2111.186085 704.7365 Polypyrimidine tract-binding protein 1 OS=Homo sapiens OX=9606 GN=PTBP1 PE=1 SV=1 4.68 3961.1 - 5.05E+06 - - - -0.8161 - 3.38 0.617 - 555.1 1 2 0 -0.0017 20 0 0 0 4.18E+07 4.25E+07 - - - 8.3731 0.9003 221125_WJC_METTL3_EV_vs_WT_F03.26051.26051.3 1.03 Dec-68 R.ELESLLSQRIYC[160.03]PDSRGR[166.11].W "sp|Q9Y2M0|FAN1_HUMAN,tr|A0A590UKC0|A0A590UKC0_HUMAN,tr|A0A590UK78|A0A590UK78_HUMAN" 3 2188.0934 - 40236 26051 3 2188.08435 730.3718 Fanconi-associated nuclease 1 OS=Homo sapiens OX=9606 GN=FAN1 PE=1 SV=4 6.27 3961.7 - 4.69E+06 - - - -4.1456 - 2.355 0.187 - 123.5 2 2 2 -0.0091 18 0 0 0 - - - - - 2.6159 0.9999 221125_WJC_METTL3_EV_vs_WT_F03.26052.26052.3 5.12E-12 22/72 K.KFESEILEAISQNSVVIIR.G sp|Q08211|DHX9_HUMAN 1 2174.1947 0.7 40237 26052 3 2174.184176 725.7388 ATP-dependent RNA helicase A OS=Homo sapiens OX=9606 GN=DHX9 PE=1 SV=4 4.79 3961.8 - 2.10E+06 - - - -4.8331 - 3.975 0.58 - 780.3 1 2 0 -0.0105 19 0 0 0 1.20E+07 1.70E+07 - - - 8.394 1 221125_WJC_METTL3_EV_vs_WT_F03.26059.26059.4 1.45E-05 20/96 R.TFHIFYYLLSGAGEHLK[136.11].T sp|P35579|MYH9_HUMAN 1 2003.0396 0.67 40242 26059 4 2003.036352 501.7672 Myosin-9 OS=Homo sapiens OX=9606 GN=MYH9 PE=1 SV=4 6.61 3962.6 - 2.96E+06 - - - -1.6385 - 3.407 0.497 - 467.6 1 2 0 -0.0033 17 0 0 0 1.01E+07 1.52E+07 - - - 3.9766 1 221125_WJC_METTL3_EV_vs_WT_F03.26060.26060.4 6.25E-10 33/192 K.VLYLGAASGTTVSHVSDIVGPDGLVYAVEFSHR[166.11].S "sp|P22087|FBRL_HUMAN,tr|M0R299|M0R299_HUMAN,tr|M0R0P1|M0R0P1_HUMAN,tr|M0QXL5|M0QXL5_HUMAN,tr|M0R2Q4|M0R2Q4_HUMAN" 5 3425.7495 0.79 40243 26060 4 3425.745534 857.4446 rRNA 2'-O-methyltransferase fibrillarin OS=Homo sapiens OX=9606 GN=FBL PE=1 SV=2 5.21 3962.7 - 3.84E+06 - - - -1.1551 - 4.807 0.556 - 450.7 1 2 0 -0.004 33 0 0 0 1.80E+07 2.29E+07 - - - 4.5354 0.9999 221125_WJC_METTL3_EV_vs_WT_F03.26062.26062.4 0.0016 21/108 R.ADLEMQIESLKEELAYLKK.N sp|P02533|K1C14_HUMAN 1 2250.1817 13.52 40245 26062 4 2250.180882 563.5527 "Keratin, type I cytoskeletal 14 OS=Homo sapiens OX=9606 GN=KRT14 PE=1 SV=4" 4.59 3962.9 - 3.27E+06 - - - -0.3795 - 3.72 0.506 - 329.2 1 2 1 -0.0009 19 0 0 0 9.25E+06 6.84E+05 - - - 4.0744 0.9999 221125_WJC_METTL3_EV_vs_WT_F03.26063.26063.4 2.47E-09 14/120 K.NQILNLTTDNANILLQIDNAR.L "sp|P13645|K1C10_HUMAN,tr|A0A1B0GVI3|A0A1B0GVI3_HUMAN" 2 2366.2554 76.67 40246 26063 4 2366.24788 592.5711 "Keratin, type I cytoskeletal 10 OS=Homo sapiens OX=9606 GN=KRT10 PE=1 SV=6" 4.21 3962.9 - 3.15E+06 - - - -3.1725 - 2.996 0.568 - 200.2 1 2 0 -0.0075 21 0 0 0 1.03E+07 1.34E+05 - - - 4.5306 1 221125_WJC_METTL3_EV_vs_WT_F03.26065.26065.3 1.05E-06 24/60 R.RGVMLAVDAVIAELKK.Q "sp|P10809|CH60_HUMAN,tr|A0A7I2V2X6|A0A7I2V2X6_HUMAN,tr|A0A7I2V599|A0A7I2V599_HUMAN,tr|E7EXB4|E7EXB4_HUMAN,tr|A0A7I2YQ71|A0A7I2YQ71_HUMAN,tr|E7ESH4|E7ESH4_HUMAN,tr|A0A7I2V5M1|A0A7I2V5M1_HUMAN,tr|A0A7I2V5K3|A0A7I2V5K3_HUMAN,tr|A0A7I2V369|A0A7I2V369_HUMAN" 9 1712.0019 1.34 40248 26065 3 1712.001494 571.6746 "60 kDa heat shock protein, mitochondrial OS=Homo sapiens OX=9606 GN=HSPD1 PE=1 SV=2" 8.59 3963.2 - 2.11E+06 - - - -0.215 - 4.286 0.587 - 1035.4 1 2 0 -0.0004 16 0 0 0 7.57E+06 5.65E+06 - - - 8.8186 1 221125_WJC_METTL3_EV_vs_WT_F03.26066.26066.4 9.38E-11 27/138 K.TC[160.03]ESDTLEALLLTASER[166.11]PK[136.11]PLLFK[136.11].G sp|Q9NYU2|UGGG1_HUMAN 1 2757.4833 0.04 40249 26066 4 2757.482385 690.3781 UDP-glucose:glycoprotein glucosyltransferase 1 OS=Homo sapiens OX=9606 GN=UGGT1 PE=1 SV=3 4.87 3963.3 - 1.92E+06 - - - -0.3278 - 4.986 0.715 - 496.6 1 2 0 -0.0009 24 0 0 0 3.98E+05 9.83E+06 - - - 5.9648 1 221125_WJC_METTL3_EV_vs_WT_F03.26071.26071.3 4.36E-10 24/84 R.K[136.11]PLVIIAEDVDGEALSTLVLNR[166.11].L "sp|P10809|CH60_HUMAN,tr|A0A7I2V2X6|A0A7I2V2X6_HUMAN,tr|A0A7I2YQK6|A0A7I2YQK6_HUMAN,tr|A0A7I2V599|A0A7I2V599_HUMAN,tr|A0A7I2YQ71|A0A7I2YQ71_HUMAN,tr|A0A7I2V5M1|A0A7I2V5M1_HUMAN,tr|A0A7I2V5K3|A0A7I2V5K3_HUMAN" 7 2382.3489 1.03 40252 26071 3 2382.345953 795.1236 "60 kDa heat shock protein, mitochondrial OS=Homo sapiens OX=9606 GN=HSPD1 PE=1 SV=2" 4.32 3964 - 6.50E+06 - - - -1.2358 - 4.829 0.65 - 706.5 1 2 0 -0.0029 22 0 0 0 1.37E+08 1.33E+08 - - - 9.5193 1 221125_WJC_METTL3_EV_vs_WT_F03.26072.26072.4 2.33E-08 30/192 K.VLYLGAASGTTVSHVSDIVGPDGLVYAVEFSHR.S "sp|P22087|FBRL_HUMAN,tr|M0R299|M0R299_HUMAN,tr|M0R0P1|M0R0P1_HUMAN,tr|M0QXL5|M0QXL5_HUMAN,tr|M0R2Q4|M0R2Q4_HUMAN" 5 3415.7412 0.79 40253 26072 4 3415.735374 854.9426 rRNA 2'-O-methyltransferase fibrillarin OS=Homo sapiens OX=9606 GN=FBL PE=1 SV=2 5.21 3964.1 - 4.46E+06 - - - -1.7118 - 4.678 0.577 - 390.2 1 2 0 -0.0058 33 0 0 0 1.80E+07 2.29E+07 - - - 4.7095 1 221125_WJC_METTL3_EV_vs_WT_F03.26076.26076.3 3.17E-06 17/72 R.GYFNEELSEILSDPSDDTK.G sp|P15924|DESP_HUMAN 1 2157.959 15.83 40257 26076 3 2157.95885 720.3269 Desmoplakin OS=Homo sapiens OX=9606 GN=DSP PE=1 SV=3 3.71 3964.3 - 5.80E+06 - - - -0.0649 - 3.182 0.602 - 215 1 2 0 -0.0001 19 0 0 0 2.96E+07 1.87E+06 - - - 8.0954 1 221125_WJC_METTL3_EV_vs_WT_F03.26077.26077.4 4.14E-12 23/156 R.GFGFVTFSSMAEVDAAMAARPHSIDGR.V "sp|P22626|ROA2_HUMAN,tr|A0A7I2YQN4|A0A7I2YQN4_HUMAN,tr|A0A7I2V4N0|A0A7I2V4N0_HUMAN,tr|A0A024RA28|A0A024RA28_HUMAN,tr|A0A7I2V4N1|A0A7I2V4N1_HUMAN,tr|A0A7I2V4I6|A0A7I2V4I6_HUMAN,tr|A0A087WUI2|A0A087WUI2_HUMAN,tr|A0A7I2V4S4|A0A7I2V4S4_HUMAN,tr|A0A7I2V323|A0A7I2V323_HUMAN,tr|A0A7I2V3P1|A0A7I2V3P1_HUMAN,tr|A0A7I2V3P7|A0A7I2V3P7_HUMAN" 11 2826.3218 0.74 40258 26077 4 2826.323091 707.5877 Heterogeneous nuclear ribonucleoproteins A2\B1 OS=Homo sapiens OX=9606 GN=HNRNPA2B1 PE=1 SV=2 5.38 3964.4 - 3.46E+06 - - - 0.4677 - 3.709 0.656 - 350.8 1 2 0 0.0013 27 0 0 0 9.73E+06 1.32E+07 - - - 5.3456 1 221125_WJC_METTL3_EV_vs_WT_F03.26078.26078.3 3.43E-06 28/84 K.ASAISVTVLNVIEGPVFRPGSK.T sp|Q02413|DSG1_HUMAN 1 2240.2529 999 40259 26078 3 2240.251305 747.7582 Desmoglein-1 OS=Homo sapiens OX=9606 GN=DSG1 PE=1 SV=2 8.79 3964.4 - 3.25E+06 - - - -0.6977 - 4.832 0.584 - 915.7 1 2 0 -0.0016 22 0 0 0 5.70E+07 0.00E+00 - - - 8.7853 1 221125_WJC_METTL3_EV_vs_WT_F03.26079.26079.4 3.06E-07 17/156 R.GFGFVTFSSMAEVDAAMAAR[166.11]PHSIDGR[166.11].V "sp|P22626|ROA2_HUMAN,tr|A0A7I2YQN4|A0A7I2YQN4_HUMAN,tr|A0A7I2V4N0|A0A7I2V4N0_HUMAN,tr|A0A024RA28|A0A024RA28_HUMAN,tr|A0A7I2V4N1|A0A7I2V4N1_HUMAN,tr|A0A7I2V4I6|A0A7I2V4I6_HUMAN,tr|A0A087WUI2|A0A087WUI2_HUMAN,tr|A0A7I2V4S4|A0A7I2V4S4_HUMAN,tr|A0A7I2V323|A0A7I2V323_HUMAN,tr|A0A7I2V3P1|A0A7I2V3P1_HUMAN,tr|A0A7I2V3P7|A0A7I2V3P7_HUMAN" 11 2846.3383 0.75 40260 26079 4 2846.336104 712.5919 Heterogeneous nuclear ribonucleoproteins A2\B1 OS=Homo sapiens OX=9606 GN=HNRNPA2B1 PE=1 SV=2 5.38 3964.5 - 2.88E+06 - - - -0.7747 - 2.943 0.538 - 169.9 1 2 0 -0.0022 27 0 0 0 9.73E+06 1.30E+07 - - - 4.2459 1 221125_WJC_METTL3_EV_vs_WT_F03.26080.26080.4 8.52E-07 19/96 R.TFHIFYYLLSGAGEHLK.T sp|P35579|MYH9_HUMAN 1 1995.0254 0.67 40261 26080 4 1995.025734 499.7636 Myosin-9 OS=Homo sapiens OX=9606 GN=MYH9 PE=1 SV=4 6.61 3964.6 - 2.82E+06 - - - 0.1504 - 3.162 0.498 - 425.2 1 2 0 0.0003 17 0 0 0 1.01E+07 1.52E+07 - - - 3.9602 1 221125_WJC_METTL3_EV_vs_WT_F03.26082.26082.3 5.32E-10 16/64 R.TFHIFYYLLSGAGEHLK[136.11].T sp|P35579|MYH9_HUMAN 1 2003.0396 0.03 40263 26082 3 2003.041265 668.6872 Myosin-9 OS=Homo sapiens OX=9606 GN=MYH9 PE=1 SV=4 6.61 3964.8 - 2.48E+06 - - - 0.8143 - 3.149 0.593 - 397.2 1 2 0 0.0016 17 0 0 0 4.31E+05 1.52E+07 - - - 8.0488 1 221125_WJC_METTL3_EV_vs_WT_F03.26084.26084.3 1.85E-08 18/76 R.ATTLSNAVSSLASTGLSLTK.V "sp|Q13492|PICAL_HUMAN,tr|H0YEF7|H0YEF7_HUMAN,tr|H0YEH1|H0YEH1_HUMAN" 3 1921.0368 1.34 40265 26084 3 1921.037278 641.3529 Phosphatidylinositol-binding clathrin assembly protein OS=Homo sapiens OX=9606 GN=PICALM PE=1 SV=2 8.8 3965 - 1.53E+06 - - - 0.2556 - 3.406 0.542 - 437.4 1 2 0 0.0005 20 0 0 0 1.36E+07 1.02E+07 - - - 7.5558 1 221125_WJC_METTL3_EV_vs_WT_F03.26086.26086.3 0.000138 13/44 R.NLDLDSIIAEVK.A "sp|P48668|K2C6C_HUMAN,sp|P04259|K2C6B_HUMAN,sp|P13647|K2C5_HUMAN,sp|P35908|K22E_HUMAN,sp|O95678|K2C75_HUMAN,sp|Q5XKE5|K2C79_HUMAN,sp|P02538|K2C6A_HUMAN,tr|H0YI76|H0YI76_HUMAN,tr|H0YIN9|H0YIN9_HUMAN" 9 1328.7187 999 40267 26086 3 1328.716249 443.9135 "Keratin, type II cytoskeletal 6C OS=Homo sapiens OX=9606 GN=KRT6C PE=1 SV=3" 4.03 3965.2 - 1.17E+06 - - - -1.88 - 2.62 0.478 - 355.3 1 2 0 -0.0025 12 0 0 0 8.83E+06 0.00E+00 - - - 6.5383 0.9999 221125_WJC_METTL3_EV_vs_WT_F03.26090.26090.2 0.000397 22-Dec R.SLDLDSIIAEVK.A sp|P04264|K2C1_HUMAN 1 1301.7078 598.62 40269 26090 2 1301.707908 651.8612 "Keratin, type II cytoskeletal 1 OS=Homo sapiens OX=9606 GN=KRT1 PE=1 SV=6" 4.03 3965.8 - 1.09E+07 - - - 0.0461 - 2.547 0.471 - 303.3 1 2 0 0.0001 12 0 0 0 1.58E+08 2.64E+05 - - - 4.9797 1 221125_WJC_METTL3_EV_vs_WT_F03.26091.26091.3 1.35E-11 21/80 K.DAASLESQLQDTQELLQEETR[166.11].Q sp|P35580|MYH10_HUMAN 1 2413.1484 1.02 40270 26091 3 2413.144141 805.3901 Myosin-10 OS=Homo sapiens OX=9606 GN=MYH10 PE=1 SV=3 3.77 3965.9 - 3.80E+06 - - - -1.7699 - 4.061 0.658 - 519.5 1 2 0 -0.0043 21 0 0 0 2.09E+07 2.05E+07 - - - 9.2347 1 221125_WJC_METTL3_EV_vs_WT_F03.26092.26092.3 4.25E-11 16/80 K.DAASLESQLQDTQELLQEETR.Q sp|P35580|MYH10_HUMAN 1 2403.1401 1.02 40271 26092 3 2403.135461 802.054 Myosin-10 OS=Homo sapiens OX=9606 GN=MYH10 PE=1 SV=3 3.77 3965.9 - 3.95E+06 - - - -1.9479 - 3.499 0.67 - 303.7 1 2 0 -0.0047 21 0 0 0 2.09E+07 2.05E+07 - - - 9.0113 1 221125_WJC_METTL3_EV_vs_WT_F03.26093.26093.4 1.58E-10 29/126 R.KPLVIIAEDVDGEALSTLVLNR.L "sp|P10809|CH60_HUMAN,tr|A0A7I2V2X6|A0A7I2V2X6_HUMAN,tr|A0A7I2YQK6|A0A7I2YQK6_HUMAN,tr|A0A7I2V599|A0A7I2V599_HUMAN,tr|A0A7I2YQ71|A0A7I2YQ71_HUMAN,tr|A0A7I2V5M1|A0A7I2V5M1_HUMAN,tr|A0A7I2V5K3|A0A7I2V5K3_HUMAN" 7 2364.3264 1.47 40272 26093 4 2364.326844 592.0889 "60 kDa heat shock protein, mitochondrial OS=Homo sapiens OX=9606 GN=HSPD1 PE=1 SV=2" 4.32 3966 - 3.29E+06 - - - 0.1764 - 4.797 0.651 - 681 1 2 0 0.0004 22 0 0 0 2.40E+07 1.63E+07 - - - 5.4052 1 221125_WJC_METTL3_EV_vs_WT_F03.26094.26094.4 1.79E-14 30/126 R.K[136.11]PLVIIAEDVDGEALSTLVLNR[166.11].L "sp|P10809|CH60_HUMAN,tr|A0A7I2V2X6|A0A7I2V2X6_HUMAN,tr|A0A7I2YQK6|A0A7I2YQK6_HUMAN,tr|A0A7I2V599|A0A7I2V599_HUMAN,tr|A0A7I2YQ71|A0A7I2YQ71_HUMAN,tr|A0A7I2V5M1|A0A7I2V5M1_HUMAN,tr|A0A7I2V5K3|A0A7I2V5K3_HUMAN" 7 2382.3489 1.44 40273 26094 4 2382.348294 596.5945 "60 kDa heat shock protein, mitochondrial OS=Homo sapiens OX=9606 GN=HSPD1 PE=1 SV=2" 4.32 3966.1 - 3.12E+06 - - - -0.2531 - 4.915 0.736 - 766.6 1 2 0 -0.0006 22 0 0 0 2.36E+07 1.63E+07 - - - 6.153 1 221125_WJC_METTL3_EV_vs_WT_F03.26096.26096.2 8.13E-12 19/36 R.GYFNEELSEILSDPSDDTK.G sp|P15924|DESP_HUMAN 1 2157.959 999 40275 26096 2 2157.957817 1079.9868 Desmoplakin OS=Homo sapiens OX=9606 GN=DSP PE=1 SV=3 3.71 3966.3 - 1.35E+06 - - - -0.5436 - 3.378 0.714 - 596.2 1 2 0 -0.0012 19 0 0 0 1.38E+07 0.00E+00 - - - 7.307 1 221125_WJC_METTL3_EV_vs_WT_F03.26098.26098.4 5.68E-12 26/108 R.TDLEMQIEGLKEELAYLRK.N sp|P08779|K1C16_HUMAN 1 2278.1879 999 40277 26098 4 2278.185729 570.5542 "Keratin, type I cytoskeletal 16 OS=Homo sapiens OX=9606 GN=KRT16 PE=1 SV=4" 4.58 3966.5 - 1.18E+06 - - - -0.9459 - 4.63 0.643 - 742.6 1 2 1 -0.0022 19 0 0 0 6.23E+06 0.00E+00 - - - 5.3405 0.9999 221125_WJC_METTL3_EV_vs_WT_F03.26099.26099.3 6.72E-05 17/44 R.SLDLDSIIAEVK.A sp|P04264|K2C1_HUMAN 1 1301.7078 999 40278 26099 3 1301.707269 434.9099 "Keratin, type II cytoskeletal 1 OS=Homo sapiens OX=9606 GN=KRT1 PE=1 SV=6" 4.03 3966.6 - 1.12E+06 - - - -0.4448 - 2.813 0.394 - 561.4 1 2 0 -0.0006 12 0 0 0 1.22E+07 0.00E+00 - - - 5.7993 1 221125_WJC_METTL3_EV_vs_WT_F03.26112.26112.3 6.60E-09 21/56 R.HDADGQATLLNLLLR.N sp|O43242|PSMD3_HUMAN 1 1648.8897 0.39 40289 26112 3 1648.887703 550.6372 26S proteasome non-ATPase regulatory subunit 3 OS=Homo sapiens OX=9606 GN=PSMD3 PE=1 SV=2 5.21 3968.1 - 1.09E+06 - - - -1.1923 - 3.847 0.652 - 925.1 1 2 0 -0.002 15 0 0 0 8.77E+06 2.22E+07 - - - 9.3242 1 221125_WJC_METTL3_EV_vs_WT_F03.26113.26113.3 2.24E-08 20/92 R.MSFGEIEEDAYQEDLGFSLGHLGK.S "sp|Q8WWY3|PRP31_HUMAN,tr|E7EVX8|E7EVX8_HUMAN" 2 2671.2112 -1 40290 26113 3 2671.202583 891.411 U4\U6 small nuclear ribonucleoprotein Prp31 OS=Homo sapiens OX=9606 GN=PRPF31 PE=1 SV=2 4.08 3968.2 - 1.07E+06 - - - -3.2255 - 3.77 0.633 - 352.6 1 2 0 -0.0086 24 0 0 0 0.00E+00 0.00E+00 - - - 8.6772 0.9999 221125_WJC_METTL3_EV_vs_WT_F03.26117.26117.4 2.77E-07 21/180 K.AKGPVTIPYPLFQSHVEDLYVEGLPEGIPFR.R "sp|P78347|GTF2I_HUMAN,tr|A0A494C1K3|A0A494C1K3_HUMAN" 2 3467.8129 3.06 40292 26117 4 3467.816151 867.9605 General transcription factor II-I OS=Homo sapiens OX=9606 GN=GTF2I PE=1 SV=2 4.83 3968.7 - 2.14E+06 - - - 0.9291 - 3.106 0.499 - 110.5 1 2 1 0.0032 31 0 0 0 1.24E+07 4.06E+06 - - - 3.9129 1 221125_WJC_METTL3_EV_vs_WT_F03.26118.26118.3 3.70E-17 27/116 K.DMAIATGGAVFGEEGLTLNLEDVQPHDLGK.V "sp|P10809|CH60_HUMAN,tr|A0A7I2V2X6|A0A7I2V2X6_HUMAN,tr|A0A7I2YQK6|A0A7I2YQK6_HUMAN,tr|A0A7I2V599|A0A7I2V599_HUMAN" 4 3096.5074 1.67 40293 26118 3 3096.499857 1033.1764 "60 kDa heat shock protein, mitochondrial OS=Homo sapiens OX=9606 GN=HSPD1 PE=1 SV=2" 4.01 3968.9 - 1.77E+06 - - - -2.4298 - 4.677 0.705 - 457.8 1 2 0 -0.0075 30 0 0 0 2.65E+07 1.59E+07 - - - 9.9471 1 221125_WJC_METTL3_EV_vs_WT_F03.26119.26119.3 1.64E-10 24/112 R.GVFPEGEGDGSLPEDHFSELPQVDTILFK.D "sp|Q8IWZ3|ANKH1_HUMAN,tr|E9PDP5|E9PDP5_HUMAN" 2 3158.5084 3.97 40294 26119 3 3158.503245 1053.8434 Ankyrin repeat and KH domain-containing protein 1 OS=Homo sapiens OX=9606 GN=ANKHD1 PE=1 SV=1 3.95 3969 - 1.82E+06 - - - -1.6406 - 3.717 0.677 - 390.7 1 2 0 -0.0052 29 0 0 0 1.01E+07 2.54E+06 - - - 9.107 1 221125_WJC_METTL3_EV_vs_WT_F03.26124.26124.3 7.93E-12 19/100 R.DNYVPEVSALDQEIIEVDPDTKEMLK.L "sp|P08708|RS17_HUMAN,tr|H3BNC9|H3BNC9_HUMAN,tr|H0YN88|H0YN88_HUMAN,tr|A0A075B716|A0A075B716_HUMAN" 4 2989.4478 1.55 40297 26124 3 2989.448263 997.4899 40S ribosomal protein S17 OS=Homo sapiens OX=9606 GN=RPS17 PE=1 SV=2 3.85 3969.7 - 7.38E+06 - - - 0.1549 - 3.571 0.598 - 148.6 1 2 1 0.0005 26 0 0 0 7.33E+07 4.73E+07 - - - 8.1353 0.9999 221125_WJC_METTL3_EV_vs_WT_F03.26127.26127.3 1.98E-07 17/64 R.EK[136.11]DGDLYILAQNFFYEK[136.11].L sp|Q7LGA3|HS2ST_HUMAN 1 2108.0437 1.04 40300 26127 3 2108.044724 703.6885 Heparan sulfate 2-O-sulfotransferase 1 OS=Homo sapiens OX=9606 GN=HS2ST1 PE=1 SV=1 4.32 3969.9 - 2.32E+06 - - - 0.4748 - 3.432 0.528 - 461.4 1 2 1 0.001 17 0 0 0 3.22E+07 3.10E+07 - - - 7.5417 0.9999 221125_WJC_METTL3_EV_vs_WT_F03.26128.26128.3 0.000119 21/72 K.ERFSPLTTNLINLLAENGR.L "sp|P48047|ATPO_HUMAN,tr|H7C0C1|H7C0C1_HUMAN,tr|A0A494C0K9|A0A494C0K9_HUMAN" 3 2157.1542 0.58 40301 26128 3 2157.157976 720.0587 "ATP synthase subunit O, mitochondrial OS=Homo sapiens OX=9606 GN=ATP5PO PE=1 SV=1" 6.24 3970 - 702777 - - - 1.743 - 4.03 0.557 - 594.5 1 2 1 0.0038 19 0 0 0 7.40E+06 1.28E+07 - - - 8.1732 0.9998 221125_WJC_METTL3_EV_vs_WT_F03.26129.26129.3 6.64E-05 15/64 R.ELAILLGMLDPAEK[136.11]DEK[136.11].G sp|P30041|PRDX6_HUMAN 1 1900.0198 2.36 40302 26129 3 1900.017656 634.3472 Peroxiredoxin-6 OS=Homo sapiens OX=9606 GN=PRDX6 PE=1 SV=3 4.18 3970.2 - 701261 - - - -1.1368 - 2.766 0.432 - 232 1 2 1 -0.0022 17 0 0 0 1.58E+07 6.73E+06 - - - 5.926 1 221125_WJC_METTL3_EV_vs_WT_F03.26134.26134.3 4.19E-12 25/100 R.DNYVPEVSALDQEIIEVDPDTK[136.11]EMLK[136.11].L "sp|P08708|RS17_HUMAN,tr|H3BNC9|H3BNC9_HUMAN,tr|H0YN88|H0YN88_HUMAN,tr|A0A075B716|A0A075B716_HUMAN" 4 3005.4762 1.7 40305 26134 3 3005.470887 1002.8327 40S ribosomal protein S17 OS=Homo sapiens OX=9606 GN=RPS17 PE=1 SV=2 3.85 3970.8 - 6.03E+06 - - - -1.7678 - 4.242 0.707 - 348.1 1 2 1 -0.0053 26 0 0 0 8.06E+07 4.73E+07 - - - 9.7454 0.9804 221125_WJC_METTL3_EV_vs_WT_F03.26135.26135.4 1.33E-07 22/162 K.FAVVMADPPWDIHMELPYGTLTDDEMR[166.11]R[166.11].L sp|Q86U44|MTA70_HUMAN 1 3324.5521 0.001 40306 26135 4 3325.539058 832.1453 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 4.23 3970.8 - 3.31E+06 - - - 296.8794 - 3.588 0.493 - 157.6 1 2 0 0.987 28 0 0 0 0.00E+00 1.11E+08 - - - 3.6403 1 221125_WJC_METTL3_EV_vs_WT_F03.26136.26136.3 3.49E-09 18/80 R.VHTVEDYQAIVDAEWNILYDK[136.11].L sp|Q99832|TCPH_HUMAN 1 2528.2315 0.55 40307 26136 3 2528.221925 843.7511 T-complex protein 1 subunit eta OS=Homo sapiens OX=9606 GN=CCT7 PE=1 SV=2 4.1 3970.9 - 2.59E+06 - - - -3.7754 - 4.074 0.649 - 455.7 1 2 0 -0.0095 21 0 0 0 1.15E+07 2.10E+07 - - - 9.1406 1 221125_WJC_METTL3_EV_vs_WT_F03.26137.26137.4 8.81E-07 18/132 R.TVPAHVETVVLFFPDVWHC[160.03]LPTR.S "sp|Q8IX12|CCAR1_HUMAN,tr|F5H2E6|F5H2E6_HUMAN,tr|F5H1H2|F5H1H2_HUMAN,tr|A0A0C4DGG8|A0A0C4DGG8_HUMAN" 4 2719.3945 1.04 40308 26137 4 2719.401642 680.8559 Cell division cycle and apoptosis regulator protein 1 OS=Homo sapiens OX=9606 GN=CCAR1 PE=1 SV=2 5.92 3971 - 790171 - - - 2.6396 - 3.485 0.549 - 191.1 1 2 0 0.0072 23 0 0 0 5.81E+06 5.60E+06 - - - 4.407 0.9989 221125_WJC_METTL3_EV_vs_WT_F03.26138.26138.3 0.00749 Oct-56 R.HDADGQATLLNLLLR[166.11].N sp|O43242|PSMD3_HUMAN 1 1658.8979 0.39 40309 26138 3 1658.895769 553.9733 26S proteasome non-ATPase regulatory subunit 3 OS=Homo sapiens OX=9606 GN=PSMD3 PE=1 SV=2 5.21 3971.2 - 347215 - - - -1.3081 - 1.801 0.291 - 108.1 1 2 0 -0.0022 15 0 0 0 8.77E+06 2.22E+07 - - - 3.319 0.9987 221125_WJC_METTL3_EV_vs_WT_F03.26141.26141.3 2.13E-09 17/56 K.STSESFIQHIVSLVH.H "sp|Q9NYF8|BCLF1_HUMAN,tr|E9PKI6|E9PKI6_HUMAN,tr|A0A1W2PQ43|A0A1W2PQ43_HUMAN,tr|E9PK91|E9PK91_HUMAN,tr|E9PJA7|E9PJA7_HUMAN,tr|E9PK09|E9PK09_HUMAN,tr|E9PQN2|E9PQN2_HUMAN" 7 1682.8628 - 40310 26141 3 1682.862126 561.9615 Bcl-2-associated transcription factor 1 OS=Homo sapiens OX=9606 GN=BCLAF1 PE=1 SV=2 5.93 3971.6 - 5.48E+06 - - - -0.3916 - 2.925 0.59 - 285.6 1 1 0 -0.0007 15 0 0 0 - - - - - 7.9184 1 221125_WJC_METTL3_EV_vs_WT_F03.26142.26142.3 8.51E-10 21/116 K.DMAIATGGAVFGEEGLTLNLEDVQPHDLGK[136.11].V "sp|P10809|CH60_HUMAN,tr|A0A7I2V2X6|A0A7I2V2X6_HUMAN,tr|A0A7I2YQK6|A0A7I2YQK6_HUMAN,tr|A0A7I2V599|A0A7I2V599_HUMAN" 4 3104.5216 1.67 40311 26142 3 3105.524228 1035.8478 "60 kDa heat shock protein, mitochondrial OS=Homo sapiens OX=9606 GN=HSPD1 PE=1 SV=2" 4.01 3971.7 - 1.09E+06 - - - 322.9634 - 4.159 0.657 - 249.3 1 2 0 1.0026 30 0 0 0 2.65E+07 1.59E+07 - - - 8.8662 1 221125_WJC_METTL3_EV_vs_WT_F03.26143.26143.3 3.50E-10 28/112 R.ILAAALTQHNGDAAASLTVAEQYVSAFSK.L "sp|Q9UJZ1|STML2_HUMAN,tr|A0A087WYB4|A0A087WYB4_HUMAN" 2 2946.5087 0.71 40312 26143 3 2946.508388 983.1768 "Stomatin-like protein 2, mitochondrial OS=Homo sapiens OX=9606 GN=STOML2 PE=1 SV=1" 5.32 3971.8 - 1.56E+06 - - - -0.1062 - 5.204 0.647 - 944.2 1 2 0 -0.0003 29 0 0 0 1.08E+07 1.53E+07 - - - 9.5481 1 221125_WJC_METTL3_EV_vs_WT_F03.26146.26146.3 2.03E-08 13/84 K.GNLAPQGSVPSAVSSLTDDLLK.Y sp|Q9Y6J9|TAF6L_HUMAN 1 2168.1325 0.42 40314 26146 3 2168.134131 723.7181 TAF6-like RNA polymerase II p300\CBP-associated factor-associated factor 65 kDa subunit 6L OS=Homo sapiens OX=9606 GN=TAF6L PE=1 SV=1 4.21 3972.2 - 723489 - - - 0.7624 - 3.26 0.507 - 164.8 1 2 0 0.0017 22 0 0 0 1.06E+07 2.55E+07 - - - 6.9938 1 221125_WJC_METTL3_EV_vs_WT_F03.26150.26150.3 2.45E-14 20/68 R.GDADQASNILASFGLSAR.D "sp|P43243|MATR3_HUMAN,tr|A8MXP9|A8MXP9_HUMAN,tr|D6R991|D6R991_HUMAN,tr|A0A0R4J2E8|A0A0R4J2E8_HUMAN,tr|D6REM6|D6REM6_HUMAN" 5 1791.8751 1.48 40317 26150 3 1791.875832 598.299 Matrin-3 OS=Homo sapiens OX=9606 GN=MATR3 PE=1 SV=2 4.21 3972.6 - 2.85E+06 - - - 0.3856 - 3.731 0.677 - 557.8 1 2 0 0.0007 18 0 0 0 8.79E+08 5.95E+08 - - - 9.3663 1 221125_WJC_METTL3_EV_vs_WT_F03.26151.26151.2 5.00E-13 24/34 R.GDADQASNILASFGLSAR.D "sp|P43243|MATR3_HUMAN,tr|A8MXP9|A8MXP9_HUMAN,tr|D6R991|D6R991_HUMAN,tr|A0A0R4J2E8|A0A0R4J2E8_HUMAN,tr|D6REM6|D6REM6_HUMAN" 5 1791.8751 1.41 40318 26151 2 1791.874985 896.9448 Matrin-3 OS=Homo sapiens OX=9606 GN=MATR3 PE=1 SV=2 4.21 3972.7 - 2.70E+06 - - - -0.0871 - 4.108 0.681 - 1794 1 2 0 -0.0002 18 0 0 0 1.43E+09 1.01E+09 - - - 7.5446 0.9999 221125_WJC_METTL3_EV_vs_WT_F03.26152.26152.3 1.17E-07 20/72 K.INDRFEFPEQLPLDEFLQK.T "sp|Q93009|UBP7_HUMAN,tr|A0A669KBL1|A0A669KBL1_HUMAN,tr|F5H2X1|F5H2X1_HUMAN,tr|H3BND8|H3BND8_HUMAN" 4 2377.1954 0.31 40319 26152 3 2377.196114 793.4057 Ubiquitin carboxyl-terminal hydrolase 7 OS=Homo sapiens OX=9606 GN=USP7 PE=1 SV=2 4.18 3972.8 - 2.18E+06 - - - 0.2949 - 3.212 0.481 - 428.5 1 2 1 0.0007 19 0 0 0 7.76E+06 2.48E+07 - - - 6.7693 0.9998 221125_WJC_METTL3_EV_vs_WT_F03.26154.26154.3 7.96E-08 15/88 R.IAIPGLAGAGNSVLLVSNLNPER.V "sp|P26599|PTBP1_HUMAN,tr|A0A0U1RRM4|A0A0U1RRM4_HUMAN,tr|A6NLN1|A6NLN1_HUMAN,tr|A0A7I2V621|A0A7I2V621_HUMAN,tr|K7EK45|K7EK45_HUMAN" 5 2274.2696 1.25 40321 26154 3 2274.279508 759.0971 Polypyrimidine tract-binding protein 1 OS=Homo sapiens OX=9606 GN=PTBP1 PE=1 SV=1 6 3973 - 979433 - - - 4.3649 - 3.402 0.552 - 242.9 1 2 0 0.0099 23 0 0 0 9.67E+06 7.72E+06 - - - 7.5638 0.9998 221125_WJC_METTL3_EV_vs_WT_F03.26158.26158.4 2.01E-06 25/138 R.LIILDEIHLLHDDRGPVLEALVAR.A "sp|O75643|U520_HUMAN,tr|A0A494C1A5|A0A494C1A5_HUMAN" 2 2719.5385 3.56 40325 26158 4 2719.533846 680.8919 U5 small nuclear ribonucleoprotein 200 kDa helicase OS=Homo sapiens OX=9606 GN=SNRNP200 PE=1 SV=2 4.8 3973.5 - 496159 - - - -1.7058 - 3.622 0.48 - 352.1 1 2 1 -0.0046 24 0 0 0 2.78E+06 7.82E+05 - - - 3.8157 0.9964 221125_WJC_METTL3_EV_vs_WT_F03.26159.26159.3 0.00123 Oct-84 R.QITK[136.11]EDFATFDYILC[160.03]MDESNLR[166.11].D sp|P24666|PPAC_HUMAN 1 2726.2687 -1 40326 26159 3 2726.26172 909.7635 Low molecular weight phosphotyrosine protein phosphatase OS=Homo sapiens OX=9606 GN=ACP1 PE=1 SV=3 4.11 3973.6 - 448725 - - - -2.5507 - 1.816 0.385 - 43.5 1 2 1 -0.007 22 0 0 0 0.00E+00 0.00E+00 - - - 4.245 0.9999 221125_WJC_METTL3_EV_vs_WT_F03.26162.26162.3 0.000869 Dec-68 R.GGHPPAIQSLINLLADNR.Y sp|Q9HCD5|NCOA5_HUMAN 1 1885.017 2.89 40328 26162 3 1885.020187 629.3463 Nuclear receptor coactivator 5 OS=Homo sapiens OX=9606 GN=NCOA5 PE=1 SV=2 6.74 3973.9 - 874277 - - - 1.6934 - 2.643 0.41 - 148 1 2 0 0.0032 18 0 0 0 2.07E+07 7.15E+06 - - - 5.5304 1 221125_WJC_METTL3_EV_vs_WT_F03.26163.26163.2 6.30E-11 22/34 R.GDADQASNILASFGLSAR[166.11].D "sp|P43243|MATR3_HUMAN,tr|A8MXP9|A8MXP9_HUMAN,tr|D6R991|D6R991_HUMAN,tr|A0A0R4J2E8|A0A0R4J2E8_HUMAN,tr|D6REM6|D6REM6_HUMAN" 5 1801.8834 1.41 40329 26163 2 1801.879203 901.949 Matrin-3 OS=Homo sapiens OX=9606 GN=MATR3 PE=1 SV=2 4.21 3974 - 6.72E+07 - - - -2.3353 - 4.106 0.73 - 1531.4 1 2 0 -0.0042 18 0 0 0 1.43E+09 1.01E+09 - - - 7.904 1 221125_WJC_METTL3_EV_vs_WT_F03.26164.26164.3 6.07E-10 17/68 R.GDADQASNILASFGLSAR[166.11].D "sp|P43243|MATR3_HUMAN,tr|A8MXP9|A8MXP9_HUMAN,tr|D6R991|D6R991_HUMAN,tr|A0A0R4J2E8|A0A0R4J2E8_HUMAN,tr|D6REM6|D6REM6_HUMAN" 5 1801.8834 1.48 40330 26164 3 1801.879129 601.6351 Matrin-3 OS=Homo sapiens OX=9606 GN=MATR3 PE=1 SV=2 4.21 3974 - 6.06E+07 - - - -2.3764 - 3.242 0.65 - 410.5 1 2 0 -0.0043 18 0 0 0 8.79E+08 5.95E+08 - - - 8.7145 1 221125_WJC_METTL3_EV_vs_WT_F03.26170.26170.3 1.93E-13 21/52 K.RNAAENMLEILGFK.V "sp|O95793|STAU1_HUMAN,tr|Q5JW30|Q5JW30_HUMAN" 2 1604.8345 2.98 40336 26170 3 1604.83224 535.9521 Double-stranded RNA-binding protein Staufen homolog 1 OS=Homo sapiens OX=9606 GN=STAU1 PE=1 SV=2 6.14 3974.4 - 1.41E+06 - - - -1.3846 - 3.753 0.702 - 780.7 1 2 0 -0.0022 14 0 0 0 6.60E+06 2.21E+06 - - - 9.8807 1 221125_WJC_METTL3_EV_vs_WT_F03.26171.26171.3 1.05E-17 25/96 K.LMSDPDSSIIDFYPEDFAIDLNGK[136.11]K[136.11].Y sp|Q9H0D6|XRN2_HUMAN 1 2845.3703 0.86 40337 26171 3 2845.359085 949.464 5'-3' exoribonuclease 2 OS=Homo sapiens OX=9606 GN=XRN2 PE=1 SV=1 3.9 3974.5 - 1.30E+06 - - - -3.9341 - 4.686 0.762 - 572 1 2 0 -0.0112 25 0 0 0 6.41E+06 7.45E+06 - - - 10.586 0.9943 221125_WJC_METTL3_EV_vs_WT_F03.26174.26174.3 0.0218 Nov-60 R.K[136.11]VVEYSDVILEVLDAR[166.11].D "sp|Q9NVN8|GNL3L_HUMAN,tr|A0A6I8PL80|A0A6I8PL80_HUMAN,tr|A0A6I8PS19|A0A6I8PS19_HUMAN" 3 1865.0265 -1 40340 26174 3 1865.021051 622.6828 Guanine nucleotide-binding protein-like 3-like protein OS=Homo sapiens OX=9606 GN=GNL3L PE=1 SV=1 4.32 3974.8 - 492866 - - - -2.9217 - 1.863 0.255 - 124.9 1 2 0 -0.0054 16 0 0 0 0.00E+00 0.00E+00 - - - 2.9779 0.9999 221125_WJC_METTL3_EV_vs_WT_F03.26177.26177.4 8.60E-08 20/162 K.NIILEEGKEILVGDVGQTVDDPYATFVK.M "sp|P23528|COF1_HUMAN,tr|E9PP50|E9PP50_HUMAN,tr|G3V1A4|G3V1A4_HUMAN,tr|E9PQB7|E9PQB7_HUMAN,tr|E9PK25|E9PK25_HUMAN,tr|E9PLJ3|E9PLJ3_HUMAN,tr|E9PS23|E9PS23_HUMAN" 7 3061.5859 0.69 40342 26177 4 3061.58462 766.4038 Cofilin-1 OS=Homo sapiens OX=9606 GN=CFL1 PE=1 SV=3 4.02 3975.1 - 1.62E+06 - - - -0.4341 - 4.137 0.587 - 212.5 1 2 1 -0.0013 28 0 0 0 2.81E+07 4.05E+07 - - - 4.7758 1 221125_WJC_METTL3_EV_vs_WT_F03.26179.26179.3 2.40E-11 19/80 R.AIEALKEFNEDGALAVLQQFK.D "sp|O60506|HNRPQ_HUMAN,tr|A0A7I2YQV8|A0A7I2YQV8_HUMAN,tr|A0A7I2YQN2|A0A7I2YQN2_HUMAN,tr|A0A7I2V5Q6|A0A7I2V5Q6_HUMAN,tr|A0A7I2V4Z0|A0A7I2V4Z0_HUMAN,tr|A0A7I2V4J0|A0A7I2V4J0_HUMAN,tr|F6UXX1|F6UXX1_HUMAN,tr|A0A7I2V346|A0A7I2V346_HUMAN" 8 2333.2267 0.71 40343 26179 3 2333.225255 778.7495 Heterogeneous nuclear ribonucleoprotein Q OS=Homo sapiens OX=9606 GN=SYNCRIP PE=1 SV=2 4.41 3975.4 - 3.20E+06 - - - -0.6249 - 3.849 0.6 - 465.2 1 2 1 -0.0015 21 0 0 0 1.41E+07 2.01E+07 - - - 8.4603 1 221125_WJC_METTL3_EV_vs_WT_F03.26182.26182.3 6.70E-10 20/64 K.K[136.11]EDLVFIFWAPESAPLK[136.11].S "sp|P23528|COF1_HUMAN,sp|Q9Y281|COF2_HUMAN,tr|E9PP50|E9PP50_HUMAN,tr|G3V1A4|G3V1A4_HUMAN,tr|E9PQB7|E9PQB7_HUMAN,tr|E9PK25|E9PK25_HUMAN" 6 2005.0896 1.52 40346 26182 3 2005.085704 669.3705 Cofilin-1 OS=Homo sapiens OX=9606 GN=CFL1 PE=1 SV=3 4.68 3975.8 - 2.12E+06 - - - -1.9186 - 3.303 0.601 - 488.7 1 2 0 -0.0038 17 0 0 0 2.03E+07 1.33E+07 - - - 8.258 0.9997 221125_WJC_METTL3_EV_vs_WT_F03.26183.26183.3 0.00579 14/68 R.DSIFSNLTGQLDYQGFEK[136.11].A "sp|P40939|ECHA_HUMAN,tr|A0A2R8YG21|A0A2R8YG21_HUMAN,tr|H0YFD6|H0YFD6_HUMAN,tr|A0A2R8Y4F5|A0A2R8Y4F5_HUMAN" 4 2068.9833 0.89 40347 26183 3 2068.97577 690.6684 "Trifunctional enzyme subunit alpha, mitochondrial OS=Homo sapiens OX=9606 GN=HADHA PE=1 SV=2" 4.03 3975.9 - 1.84E+06 - - - -3.64 - 2.744 0.429 - 280.5 1 2 0 -0.0075 18 0 0 0 5.44E+06 6.08E+06 - - - 5.8344 1 221125_WJC_METTL3_EV_vs_WT_F03.26187.26187.3 2.75E-07 23/64 K.KEDLVFIFWAPESAPLK.S "sp|P23528|COF1_HUMAN,sp|Q9Y281|COF2_HUMAN,tr|E9PP50|E9PP50_HUMAN,tr|G3V1A4|G3V1A4_HUMAN,tr|E9PQB7|E9PQB7_HUMAN,tr|E9PK25|E9PK25_HUMAN" 6 1989.0612 1.52 40349 26187 3 1989.058819 664.0277 Cofilin-1 OS=Homo sapiens OX=9606 GN=CFL1 PE=1 SV=3 4.68 3976.3 - 4.07E+06 - - - -1.1724 - 4.049 0.601 - 697.9 1 2 0 -0.0023 17 0 0 0 2.03E+07 1.33E+07 - - - 8.7729 1 221125_WJC_METTL3_EV_vs_WT_F03.26190.26190.2 7.22E-08 15/26 K.GQSEDPGSLLSLFR[166.11].R "sp|P08195|4F2_HUMAN,tr|A0A7P0TAN7|A0A7P0TAN7_HUMAN,tr|J3KPF3|J3KPF3_HUMAN,tr|F5H056|F5H056_HUMAN,tr|F5GZI0|F5GZI0_HUMAN,tr|A0A7P0T9F7|A0A7P0T9F7_HUMAN,tr|A0A7P0TBF8|A0A7P0TBF8_HUMAN,tr|A0A7P0Z4A0|A0A7P0Z4A0_HUMAN,tr|F5GZS6|F5GZS6_HUMAN,tr|A0A7P0Z4P5|A0A7P0Z4P5_HUMAN" 10 1514.7604 1.4 40352 26190 2 1514.75859 758.3875 4F2 cell-surface antigen heavy chain OS=Homo sapiens OX=9606 GN=SLC3A2 PE=1 SV=3 4.37 3976.6 - 2.06E+06 - - - -1.2226 - 3.094 0.629 - 590.3 1 2 0 -0.0019 14 0 0 0 1.57E+07 1.12E+07 - - - 6.5205 1 221125_WJC_METTL3_EV_vs_WT_F03.26197.26197.3 6.50E-11 22/72 R.YPEDKITPENLPQILLQLK.R "sp|P43243|MATR3_HUMAN,tr|A8MXP9|A8MXP9_HUMAN,tr|D6R991|D6R991_HUMAN,tr|A0A0R4J2E8|A0A0R4J2E8_HUMAN,tr|D6REM6|D6REM6_HUMAN" 5 2251.2464 1.53 40357 26197 3 2251.246766 751.4227 Matrin-3 OS=Homo sapiens OX=9606 GN=MATR3 PE=1 SV=2 4.68 3977.6 - 4.35E+06 - - - 0.1692 - 3.514 0.697 - 555.7 1 2 1 0.0004 19 0 0 0 8.96E+07 5.86E+07 - - - 9.3984 1 221125_WJC_METTL3_EV_vs_WT_F03.26199.26199.3 9.32E-05 21/72 R.YPEDK[136.11]ITPENLPQILLQLK[136.11].R "sp|P43243|MATR3_HUMAN,tr|A8MXP9|A8MXP9_HUMAN,tr|D6R991|D6R991_HUMAN,tr|A0A0R4J2E8|A0A0R4J2E8_HUMAN,tr|D6REM6|D6REM6_HUMAN" 5 2267.2748 1.53 40359 26199 3 2267.273293 756.7655 Matrin-3 OS=Homo sapiens OX=9606 GN=MATR3 PE=1 SV=2 4.68 3977.7 - 3.48E+06 - - - -0.6581 - 3.457 0.59 - 384.1 1 2 1 -0.0015 19 0 0 0 8.96E+07 5.86E+07 - - - 8.1649 0.9952 221125_WJC_METTL3_EV_vs_WT_F03.26200.26200.3 5.13E-10 23/80 M.NVGTRPINLEPIFQGYIDSLK.R sp|P35908|K22E_HUMAN 1 2373.2692 2.56 40360 26200 3 2373.264519 792.097 "Keratin, type II cytoskeletal 2 epidermal OS=Homo sapiens OX=9606 GN=KRT2 PE=1 SV=2" 6.07 3977.8 - 1.92E+06 - - - -1.9918 - 3.903 0.44 - 517.7 1 1 0 -0.0047 21 0 0 0 1.52E+07 5.93E+06 - - - 6.709 1 221125_WJC_METTL3_EV_vs_WT_F03.26201.26201.3 1.57E-10 19/96 R.QIPVLQTNNGPSLTGLTTIAAHLVK.Q "sp|O43324|MCA3_HUMAN,tr|C9J1V9|C9J1V9_HUMAN,tr|H0YAL7|H0YAL7_HUMAN,tr|D6RBD7|D6RBD7_HUMAN" 4 2585.4541 2.11 40361 26201 3 2585.454106 862.8253 Eukaryotic translation elongation factor 1 epsilon-1 OS=Homo sapiens OX=9606 GN=EEF1E1 PE=1 SV=1 8.76 3977.9 - 1.40E+06 - - - 0.0073 - 3.483 0.649 - 242.4 1 2 0 0 25 0 0 0 1.26E+07 6.00E+06 - - - 8.6467 0.9979 221125_WJC_METTL3_EV_vs_WT_F03.26202.26202.3 1.04E-07 18/76 N.VGTRPINLEPIFQGYIDSLK.R sp|P35908|K22E_HUMAN 1 2259.2263 30.73 40362 26202 3 2259.22938 754.0827 "Keratin, type II cytoskeletal 2 epidermal OS=Homo sapiens OX=9606 GN=KRT2 PE=1 SV=2" 6.04 3978 - 1.53E+06 - - - 1.3549 - 3.782 0.512 - 286.1 1 1 0 0.0031 20 0 0 0 1.28E+07 4.15E+05 - - - 7.4747 0.9988 221125_WJC_METTL3_EV_vs_WT_F03.26203.26203.3 1.36E-06 20/72 G.VTIAQGGVLPNIQAVLLPK[136.11].K "sp|P16104|H2AX_HUMAN,sp|Q9BTM1|H2AJ_HUMAN,sp|Q93077|H2A1C_HUMAN,sp|Q99878|H2A1J_HUMAN,sp|Q16777|H2A2C_HUMAN,sp|Q8IUE6|H2A2B_HUMAN,sp|Q96QV6|H2A1A_HUMAN,sp|P04908|H2A1B_HUMAN,sp|P20671|H2A1D_HUMAN,sp|P0C0S8|H2A1_HUMAN,sp|Q6FI13|H2A2A_HUMAN,sp|Q96KK5|H2A1H_HUMAN,sp|Q7L7L0|H2A3_HUMAN,tr|A0A0U1RR32|A0A0U1RR32_HUMAN,tr|A0A0U1RRH7|A0A0U1RRH7_HUMAN,tr|H0YFX9|H0YFX9_HUMAN" 16 1938.1757 1.93 40363 26203 3 1938.17489 647.0659 Histone H2AX OS=Homo sapiens OX=9606 GN=H2AX PE=1 SV=2 8.72 3978.1 - 1.04E+06 - - - -0.4355 - 3.568 0.564 - 403 1 1 0 -0.0008 19 0 0 0 2.20E+07 1.14E+07 - - - 7.9529 0.9896 221125_WJC_METTL3_EV_vs_WT_F03.26204.26204.3 0.0512 Dec-76 R.TSETGIVDQVMVTLNQEGYK[136.11].F "sp|P30876|RPB2_HUMAN,tr|C9J4M6|C9J4M6_HUMAN,tr|C9J2Y9|C9J2Y9_HUMAN" 3 2219.0871 0.38 40364 26204 3 2219.084185 740.703 DNA-directed RNA polymerase II subunit RPB2 OS=Homo sapiens OX=9606 GN=POLR2B PE=1 SV=1 4.14 3978.2 - 993676 - - - -1.3199 - 2.015 0.147 - 116.3 1 2 0 -0.0029 20 0 0 0 1.97E+06 5.17E+06 - - - 1.8778 1 221125_WJC_METTL3_EV_vs_WT_F03.26205.26205.3 1.62E-08 19/68 R.GGHPPAIQSLINLLADNR[166.11].Y sp|Q9HCD5|NCOA5_HUMAN 1 1895.0253 2.9 40365 26205 3 1895.021152 632.6824 Nuclear receptor coactivator 5 OS=Homo sapiens OX=9606 GN=NCOA5 PE=1 SV=2 6.74 3978.3 - 746143 - - - -2.1704 - 3.771 0.532 - 482.6 1 2 0 -0.0041 18 0 0 0 2.07E+07 7.15E+06 - - - 7.7753 0.9997 221125_WJC_METTL3_EV_vs_WT_F03.26212.26212.4 3.57E-06 18/180 K.AK[136.11]GPVTIPYPLFQSHVEDLYVEGLPEGIPFR[166.11].R "sp|P78347|GTF2I_HUMAN,tr|A0A494C1K3|A0A494C1K3_HUMAN" 2 3485.8354 1.78 40370 26212 4 3485.837617 872.4661 General transcription factor II-I OS=Homo sapiens OX=9606 GN=GTF2I PE=1 SV=2 4.83 3979.2 - 4.64E+06 - - - 0.6363 - 2.58 0.436 - 91.2 1 2 1 0.0022 31 0 0 0 3.95E+07 2.21E+07 - - - 3.3084 1 221125_WJC_METTL3_EV_vs_WT_F03.26213.26213.3 2.12E-09 18/84 K.LLDFGSLSNLQVTQPTVGMNFK.T "sp|P08708|RS17_HUMAN,tr|H3BNC9|H3BNC9_HUMAN" 2 2408.241 0.85 40371 26213 3 2408.242009 803.7543 40S ribosomal protein S17 OS=Homo sapiens OX=9606 GN=RPS17 PE=1 SV=2 5.84 3979.3 - 2.30E+06 - - - 0.426 - 3.765 0.595 - 248.9 1 2 0 0.001 22 0 0 0 1.03E+07 1.22E+07 - - - 8.3165 0.998 221125_WJC_METTL3_EV_vs_WT_F03.26214.26214.3 0.00241 19/72 G.VTIAQGGVLPNIQAVLLPK.K "sp|P16104|H2AX_HUMAN,sp|Q9BTM1|H2AJ_HUMAN,sp|Q93077|H2A1C_HUMAN,sp|Q99878|H2A1J_HUMAN,sp|Q16777|H2A2C_HUMAN,sp|Q8IUE6|H2A2B_HUMAN,sp|Q96QV6|H2A1A_HUMAN,sp|P04908|H2A1B_HUMAN,sp|P20671|H2A1D_HUMAN,sp|P0C0S8|H2A1_HUMAN,sp|Q6FI13|H2A2A_HUMAN,sp|Q96KK5|H2A1H_HUMAN,sp|Q7L7L0|H2A3_HUMAN,tr|A0A0U1RR32|A0A0U1RR32_HUMAN,tr|A0A0U1RRH7|A0A0U1RRH7_HUMAN,tr|H0YFX9|H0YFX9_HUMAN" 16 1930.1615 1.93 40372 26214 3 1930.161283 644.3945 Histone H2AX OS=Homo sapiens OX=9606 GN=H2AX PE=1 SV=2 8.72 3979.4 - 2.26E+06 - - - -0.13 - 3.301 0.507 - 337.1 1 1 0 -0.0003 19 0 0 0 2.20E+07 1.14E+07 - - - 7.1265 1 221125_WJC_METTL3_EV_vs_WT_F03.26215.26215.3 5.69E-10 19/84 K.AQSSQDAVSSMNLFDLGGQYLR[166.11].V "sp|Q9UHX1|PUF60_HUMAN,tr|A0A0J9YYL3|A0A0J9YYL3_HUMAN,tr|A0A0J9YWM1|A0A0J9YWM1_HUMAN,tr|H0YEM1|H0YEM1_HUMAN,tr|A0A0J9YVR6|A0A0J9YVR6_HUMAN,tr|A0A0J9YXX5|A0A0J9YXX5_HUMAN,tr|A0A0J9YXJ8|A0A0J9YXJ8_HUMAN,tr|E9PQ56|E9PQ56_HUMAN,tr|H0YCP8|H0YCP8_HUMAN,tr|A0A0J9YVP6|A0A0J9YVP6_HUMAN" 10 2396.1306 0.75 40373 26215 3 2396.129031 799.7175 Poly(U)-binding-splicing factor PUF60 OS=Homo sapiens OX=9606 GN=PUF60 PE=1 SV=1 4.21 3979.5 - 1.57E+06 - - - -0.6523 - 3.516 0.62 - 364.4 1 2 0 -0.0016 22 0 0 0 5.02E+06 6.69E+06 - - - 8.4329 1 221125_WJC_METTL3_EV_vs_WT_F03.26226.26226.3 4.41E-07 17/96 K.LTTPTYGDLNHLVSATMSGVTTC[160.03]LR[166.11].F "sp|P04350|TBB4A_HUMAN,sp|Q9BVA1|TBB2B_HUMAN,sp|P07437|TBB5_HUMAN,sp|Q13885|TBB2A_HUMAN,sp|P68371|TBB4B_HUMAN,tr|M0R2D3|M0R2D3_HUMAN,tr|Q5ST81|Q5ST81_HUMAN,tr|Q5JP53|Q5JP53_HUMAN" 8 2717.3392 5.6 40382 26226 3 2717.33914 906.787 Tubulin beta-4A chain OS=Homo sapiens OX=9606 GN=TUBB4A PE=1 SV=2 6.73 3980.8 - 1.05E+07 - - - -0.0247 - 3.366 0.559 - 273.8 1 2 0 -0.0001 25 0 0 0 2.65E+08 4.73E+07 - - - 7.5646 1 221125_WJC_METTL3_EV_vs_WT_F03.26227.26227.3 1.86E-12 23/60 R.THNLEPYFESFINNLR.R sp|P04264|K2C1_HUMAN 1 1992.9694 206.2 40383 26227 3 1992.970056 665.3304 "Keratin, type II cytoskeletal 1 OS=Homo sapiens OX=9606 GN=KRT1 PE=1 SV=6" 5.37 3980.8 - 8.34E+06 - - - 0.3412 - 4.106 0.707 - 1086.6 1 2 0 0.0007 16 0 0 0 3.24E+08 1.57E+06 - - - 10.0463 1 221125_WJC_METTL3_EV_vs_WT_F03.26228.26228.3 8.08E-10 18/96 K.LTTPTYGDLNHLVSATMSGVTTC[160.03]LR.F "sp|P04350|TBB4A_HUMAN,sp|Q9BVA1|TBB2B_HUMAN,sp|P07437|TBB5_HUMAN,sp|Q13885|TBB2A_HUMAN,sp|P68371|TBB4B_HUMAN,tr|M0R2D3|M0R2D3_HUMAN,tr|Q5ST81|Q5ST81_HUMAN,tr|Q5JP53|Q5JP53_HUMAN" 8 2707.3309 6.19 40384 26228 3 2707.330737 903.4509 Tubulin beta-4A chain OS=Homo sapiens OX=9606 GN=TUBB4A PE=1 SV=2 6.73 3980.9 - 5.69E+06 - - - -0.0739 - 3.415 0.529 - 279.4 1 2 0 -0.0002 25 0 0 0 2.93E+08 4.73E+07 - - - 7.2634 1 221125_WJC_METTL3_EV_vs_WT_F03.26229.26229.4 2.14E-09 25/174 K.DMAIATGGAVFGEEGLTLNLEDVQPHDLGK.V "sp|P10809|CH60_HUMAN,tr|A0A7I2V2X6|A0A7I2V2X6_HUMAN,tr|A0A7I2YQK6|A0A7I2YQK6_HUMAN,tr|A0A7I2V599|A0A7I2V599_HUMAN" 4 3096.5074 1.03 40385 26229 4 3096.506328 775.1341 "60 kDa heat shock protein, mitochondrial OS=Homo sapiens OX=9606 GN=HSPD1 PE=1 SV=2" 4.01 3981 - 3.64E+06 - - - -0.3401 - 3.488 0.607 - 224 1 2 0 -0.0011 30 0 0 0 5.31E+07 5.15E+07 - - - 4.8913 1 221125_WJC_METTL3_EV_vs_WT_F03.26232.26232.3 1.02E-06 Nov-96 R.QIPVLQTNNGPSLTGLTTIAAHLVK[136.11].Q "sp|O43324|MCA3_HUMAN,tr|C9J1V9|C9J1V9_HUMAN,tr|H0YAL7|H0YAL7_HUMAN,tr|D6RBD7|D6RBD7_HUMAN" 4 2593.4683 2.11 40388 26232 3 2593.466023 865.4967 Eukaryotic translation elongation factor 1 epsilon-1 OS=Homo sapiens OX=9606 GN=EEF1E1 PE=1 SV=1 8.76 3981.3 - 1.91E+06 - - - -0.873 - 2.585 0.497 - 66.3 1 2 0 -0.0023 25 0 0 0 1.26E+07 6.00E+06 - - - 6.2654 1 221125_WJC_METTL3_EV_vs_WT_F03.26234.26234.3 0.158 16/72 K.QTPDFHTVIGDTVTGLLER.C "sp|Q9H8H0|NOL11_HUMAN,tr|J3QR28|J3QR28_HUMAN" 2 2098.0695 -1 40390 26234 3 2098.072893 700.3638 Nucleolar protein 11 OS=Homo sapiens OX=9606 GN=NOL11 PE=1 SV=1 4.54 3981.5 - 899548 - - - 1.6248 - 3.055 0.471 - 316.2 1 2 0 0.0034 19 0 0 0 0.00E+00 0.00E+00 - - - 6.5339 0.999 221125_WJC_METTL3_EV_vs_WT_F03.26236.26236.4 0.0119 15/144 K.LTTPTYGDLNHLVSATMSGVTTC[160.03]LR.F "sp|P04350|TBB4A_HUMAN,sp|Q9BVA1|TBB2B_HUMAN,sp|P07437|TBB5_HUMAN,sp|Q13885|TBB2A_HUMAN,sp|P68371|TBB4B_HUMAN,tr|M0R2D3|M0R2D3_HUMAN,tr|Q5ST81|Q5ST81_HUMAN,tr|Q5JP53|Q5JP53_HUMAN" 8 2707.3309 1.37 40392 26236 4 2707.327488 677.84 Tubulin beta-4A chain OS=Homo sapiens OX=9606 GN=TUBB4A PE=1 SV=2 6.73 3981.8 - 832543 - - - -1.2739 - 2.634 0.292 - 91.9 1 2 0 -0.0034 25 0 0 0 2.75E+06 2.00E+06 - - - 2.0747 0.9976 221125_WJC_METTL3_EV_vs_WT_F03.26237.26237.4 0.00505 10/108 R.YPEDKITPENLPQILLQLK.R "sp|P43243|MATR3_HUMAN,tr|A8MXP9|A8MXP9_HUMAN,tr|D6R991|D6R991_HUMAN,tr|A0A0R4J2E8|A0A0R4J2E8_HUMAN,tr|D6REM6|D6REM6_HUMAN" 5 2251.2464 1.32 40393 26237 4 2251.24115 563.8189 Matrin-3 OS=Homo sapiens OX=9606 GN=MATR3 PE=1 SV=2 4.68 3981.9 - 340926 - - - -2.3254 - 2.317 0.351 - 71.6 1 2 1 -0.0052 19 0 0 0 1.18E+06 8.92E+05 - - - 2.5639 0.9879 221125_WJC_METTL3_EV_vs_WT_F03.26238.26238.4 0.0144 10/108 R.YPEDK[136.11]ITPENLPQILLQLK[136.11].R "sp|P43243|MATR3_HUMAN,tr|A8MXP9|A8MXP9_HUMAN,tr|D6R991|D6R991_HUMAN,tr|A0A0R4J2E8|A0A0R4J2E8_HUMAN,tr|D6REM6|D6REM6_HUMAN" 5 2267.2748 1.32 40394 26238 4 2267.276104 567.826 Matrin-3 OS=Homo sapiens OX=9606 GN=MATR3 PE=1 SV=2 4.68 3982 - 271506 - - - 0.5818 - 1.632 0.254 - 39.6 1 2 1 0.0013 19 0 0 0 1.18E+06 8.92E+05 - - - 1.6021 1 221125_WJC_METTL3_EV_vs_WT_F03.26243.26243.3 2.74E-17 27/84 R.KPLVIIAEDVDGEALSTLVLNR.L "sp|P10809|CH60_HUMAN,tr|A0A7I2V2X6|A0A7I2V2X6_HUMAN,tr|A0A7I2YQK6|A0A7I2YQK6_HUMAN,tr|A0A7I2V599|A0A7I2V599_HUMAN,tr|A0A7I2YQ71|A0A7I2YQ71_HUMAN,tr|A0A7I2V5M1|A0A7I2V5M1_HUMAN,tr|A0A7I2V5K3|A0A7I2V5K3_HUMAN" 7 2364.3264 1.67 40397 26243 3 2364.320487 789.1161 "60 kDa heat shock protein, mitochondrial OS=Homo sapiens OX=9606 GN=HSPD1 PE=1 SV=2" 4.32 3982.5 - 3.08E+07 - - - -2.5123 - 5.003 0.643 - 910.3 1 2 0 -0.0059 22 0 0 0 3.66E+08 2.19E+08 - - - 9.5243 1 221125_WJC_METTL3_EV_vs_WT_F03.26244.26244.3 3.91E-13 19/76 K.NFGEEVDDESLKELFSQFGK.T "sp|Q13310|PABP4_HUMAN,tr|A0A7I2V5W9|A0A7I2V5W9_HUMAN,tr|B1ANR0|B1ANR0_HUMAN,tr|A0A7I2V4L7|A0A7I2V4L7_HUMAN,tr|H0YCC8|H0YCC8_HUMAN,tr|A0A7I2V598|A0A7I2V598_HUMAN,tr|H0Y5F5|H0Y5F5_HUMAN" 7 2317.075 1.09 40398 26244 3 2317.071252 773.3656 Polyadenylate-binding protein 4 OS=Homo sapiens OX=9606 GN=PABPC4 PE=1 SV=1 4.08 3982.5 - 1.99E+07 - - - -1.6275 - 3.716 0.697 - 265.1 1 2 1 -0.0038 20 0 0 0 5.06E+07 4.65E+07 - - - 9.4943 0.9512 221125_WJC_METTL3_EV_vs_WT_F03.26249.26249.3 0.000293 10/108 K.ALANVNIGSLIC[160.03]NVGAGGPAPAAGAAPA.G sp|P05386|RLA1_HUMAN 1 2473.2747 - 40403 26249 3 2473.270438 825.4322 60S acidic ribosomal protein P1 OS=Homo sapiens OX=9606 GN=RPLP1 PE=1 SV=1 5.56 3982.9 - 2.70E+06 - - - -1.7406 - 2.498 0.316 - 42.2 1 1 0 -0.0043 28 0 0 0 - - - - - 4.1681 1 221125_WJC_METTL3_EV_vs_WT_F03.26256.26256.3 5.64E-19 26/112 K.ENGTVTAANASTLNDGAAALVLMTADAAK.R "sp|P24752|THIL_HUMAN,tr|A0A5F9ZHJ7|A0A5F9ZHJ7_HUMAN,tr|A0A5F9ZHD4|A0A5F9ZHD4_HUMAN,tr|A0A5F9ZHJ0|A0A5F9ZHJ0_HUMAN,tr|A0A5F9ZHL1|A0A5F9ZHL1_HUMAN,tr|A0A5F9ZI66|A0A5F9ZI66_HUMAN" 6 2760.36 12.87 40405 26256 3 2760.361349 921.1273 "Acetyl-CoA acetyltransferase, mitochondrial OS=Homo sapiens OX=9606 GN=ACAT1 PE=1 SV=1" 4.03 3983.6 - 7.90E+06 - - - 0.4931 - 4.889 0.739 - 754.7 1 2 0 0.0014 29 0 0 0 8.11E+07 6.30E+06 - - - 10.4298 1 221125_WJC_METTL3_EV_vs_WT_F03.26274.26274.3 1.23E-11 27/80 R.VELSDVQNPAISITENVLHFK.A sp|Q9P035|HACD3_HUMAN 1 2352.2325 0.95 40412 26274 3 2352.227962 785.0848 Very-long-chain (3R)-3-hydroxyacyl-CoA dehydratase 3 OS=Homo sapiens OX=9606 GN=HACD3 PE=1 SV=2 4.65 3985.9 - 4.14E+06 - - - -1.9403 - 4.037 0.6 - 688.1 1 2 0 -0.0046 21 0 0 0 4.00E+07 4.22E+07 - - - 8.5738 1 221125_WJC_METTL3_EV_vs_WT_F03.26278.26278.3 2.72E-12 29/100 K.VGDAIPAVEVFEGEPGNKVNLAELFK.G sp|P30044|PRDX5_HUMAN 1 2741.4276 3.02 40414 26278 3 2741.427368 914.8165 "Peroxiredoxin-5, mitochondrial OS=Homo sapiens OX=9606 GN=PRDX5 PE=1 SV=4" 4.25 3986.5 - 3.03E+06 - - - -0.0835 - 4.49 0.66 - 727.4 1 2 1 -0.0002 26 0 0 0 2.67E+07 8.84E+06 - - - 9.3535 0.999 221125_WJC_METTL3_EV_vs_WT_F03.26279.26279.3 9.71E-08 17/100 K.VGDAIPAVEVFEGEPGNK[136.11]VNLAELFK[136.11].G sp|P30044|PRDX5_HUMAN 1 2757.456 3.02 40415 26279 3 2757.442394 920.1593 "Peroxiredoxin-5, mitochondrial OS=Homo sapiens OX=9606 GN=PRDX5 PE=1 SV=4" 4.25 3986.6 - 1.55E+06 - - - -4.9332 - 3.367 0.566 - 173.5 1 2 1 -0.0136 26 0 0 0 2.67E+07 8.84E+06 - - - 7.6396 0.9999 221125_WJC_METTL3_EV_vs_WT_F03.26283.26283.3 2.20E-05 16/84 R.LGSLVDEFKELVYPPDYNPEGK.V "sp|P12956|XRCC6_HUMAN,tr|B1AHC9|B1AHC9_HUMAN" 2 2508.2424 2.79 40419 26283 3 2508.238129 837.0881 X-ray repair cross-complementing protein 6 OS=Homo sapiens OX=9606 GN=XRCC6 PE=1 SV=2 4.18 3987.1 - 1.29E+06 - - - -1.7116 - 3.091 0.52 - 223.8 1 2 1 -0.0043 22 0 0 0 8.32E+06 2.99E+06 - - - 7.0118 0.9991 221125_WJC_METTL3_EV_vs_WT_F03.26287.26287.3 5.75E-09 14/76 R.SGGTEGLLAEKLEALITQTR.A sp|Q9UHB9|SRP68_HUMAN 1 2086.127 0.46 40423 26287 3 2086.117704 696.3829 Signal recognition particle subunit SRP68 OS=Homo sapiens OX=9606 GN=SRP68 PE=1 SV=2 4.78 3987.6 - 565129 - - - -4.4556 - 2.646 0.559 - 208.1 1 2 1 -0.0093 20 0 0 0 2.53E+06 5.53E+06 - - - 7.1304 1 221125_WJC_METTL3_EV_vs_WT_F03.26292.26292.3 2.89E-08 24/72 K.VQHQDALQISDVVMASLLR.M "sp|Q14974|IMB1_HUMAN,tr|J3KTM9|J3KTM9_HUMAN" 2 2122.1205 1.27 40426 26292 3 2122.118989 708.3808 Importin subunit beta-1 OS=Homo sapiens OX=9606 GN=KPNB1 PE=1 SV=2 5.21 3988.2 - 1.51E+06 - - - -0.6993 - 4.849 0.647 - 887.7 1 2 0 -0.0015 19 0 0 0 9.42E+06 7.40E+06 - - - 9.6317 0.9999 221125_WJC_METTL3_EV_vs_WT_F03.26293.26293.4 4.68E-10 26/234 R.LAGLEQAILSPGQNSGNYFAPIPLEDHAENKVDILEMLQK.A "sp|Q9NRA8|4ET_HUMAN,tr|B1AKL4|B1AKL4_HUMAN" 2 4362.2206 -1 40427 26293 4 4362.222293 1091.5624 Eukaryotic translation initiation factor 4E transporter OS=Homo sapiens OX=9606 GN=EIF4ENIF1 PE=1 SV=2 4.35 3988.3 - 1.94E+06 - - - 0.3906 - 4.316 0.561 - 264.9 1 2 1 0.0017 40 0 0 0 0.00E+00 0.00E+00 - - - 4.5306 1 221125_WJC_METTL3_EV_vs_WT_F03.26295.26295.3 3.60E-10 23/72 K.VQHQDALQISDVVMASLLR[166.11].M "sp|Q14974|IMB1_HUMAN,tr|J3KTM9|J3KTM9_HUMAN" 2 2132.1287 1.27 40429 26295 3 2132.129251 711.7169 Importin subunit beta-1 OS=Homo sapiens OX=9606 GN=KPNB1 PE=1 SV=2 5.21 3988.6 - 1.26E+06 - - - 0.2383 - 4.598 0.623 - 776.7 1 2 0 0.0005 19 0 0 0 9.42E+06 7.40E+06 - - - 9.2338 1 221125_WJC_METTL3_EV_vs_WT_F03.26296.26296.3 1.11E-06 14/76 R.TYIVEETVGQYLSNINLQGK[136.11].A sp|Q5SWX8|ODR4_HUMAN 1 2276.178 2.08 40430 26296 3 2276.176159 759.7333 Protein odr-4 homolog OS=Homo sapiens OX=9606 GN=ODR4 PE=1 SV=1 4.53 3988.7 - 1.08E+06 - - - -0.7991 - 2.636 0.549 - 191.7 1 2 0 -0.0018 20 0 0 0 7.35E+06 3.54E+06 - - - 7.0118 1 221125_WJC_METTL3_EV_vs_WT_F03.26297.26297.3 3.11E-09 18/84 R.AEPYC[160.03]SVLPGFTFIQHLPLSER.L "sp|Q9BUJ2|HNRL1_HUMAN,tr|M0QYZ0|M0QYZ0_HUMAN,tr|A0A0A0MRA5|A0A0A0MRA5_HUMAN,tr|M0R3F1|M0R3F1_HUMAN,tr|B7Z4B8|B7Z4B8_HUMAN" 5 2560.2784 0.42 40431 26297 3 2560.281098 854.4334 Heterogeneous nuclear ribonucleoprotein U-like protein 1 OS=Homo sapiens OX=9606 GN=HNRNPUL1 PE=1 SV=2 5.4 3988.9 - 1.02E+06 - - - 1.0417 - 2.919 0.625 - 282.1 1 2 0 0.0027 22 0 0 0 1.35E+07 3.23E+07 - - - 8.0471 1 221125_WJC_METTL3_EV_vs_WT_F03.26298.26298.3 5.89E-14 20/84 R.EADIDGDGQVNYEEFVQMMTAK[136.11].- "sp|P0DP25|CALM3_HUMAN,sp|P0DP23|CALM1_HUMAN,sp|P0DP24|CALM2_HUMAN,tr|Q96HY3|Q96HY3_HUMAN,tr|M0QZ52|M0QZ52_HUMAN,tr|E7EMB3|E7EMB3_HUMAN" 6 2497.0869 1.63 40432 26298 3 2497.080094 833.3696 Calmodulin-3 OS=Homo sapiens OX=9606 GN=CALM3 PE=1 SV=1 3.71 3989 - 992623 - - - -2.708 - 3.738 0.676 - 550.1 1 2 0 -0.0068 22 0 0 0 5.73E+06 3.51E+06 - - - 9.2009 1 221125_WJC_METTL3_EV_vs_WT_F03.26299.26299.3 3.98E-15 19/72 R.SPNEEYTWEEDPLAGIIPR.T "sp|P52732|KIF11_HUMAN,tr|A0A7I2YQY4|A0A7I2YQY4_HUMAN,tr|A0A7I2V3A9|A0A7I2V3A9_HUMAN,tr|A0A7I2V3V3|A0A7I2V3V3_HUMAN" 4 2215.0433 7.24 40433 26299 3 2215.037479 739.3551 Kinesin-like protein KIF11 OS=Homo sapiens OX=9606 GN=KIF11 PE=1 SV=2 3.91 3989.1 - 949496 - - - -2.641 - 3.818 0.629 - 429.3 1 2 0 -0.0058 19 0 0 0 3.72E+07 5.14E+06 - - - 8.8426 0.9999 221125_WJC_METTL3_EV_vs_WT_F03.26300.26300.4 3.22E-12 32/204 R.VAAGVLC[160.03]ELAQDKEAADAIDAEGASAPLMELLHSR.N sp|P14923|PLAK_HUMAN 1 3620.7814 999 40434 26300 4 3620.775319 906.2026 Junction plakoglobin OS=Homo sapiens OX=9606 GN=JUP PE=1 SV=3 4.19 3989.3 - 921052 - - - -1.6927 - 5.418 0.505 - 338.6 1 2 1 -0.0061 35 0 0 0 8.56E+06 0.00E+00 - - - 4.1208 0.9995 221125_WJC_METTL3_EV_vs_WT_F03.26301.26301.2 1.31E-06 20-Nov R.NPEAALSPTFR[166.11].S "sp|Q86U44|MTA70_HUMAN,tr|B4E349|B4E349_HUMAN,tr|F5H6D8|F5H6D8_HUMAN,tr|B4DTN4|B4DTN4_HUMAN" 4 1211.6174 0.02 40435 26301 2 1211.621357 606.816 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 6 3989.4 - 483820 - - - 3.2601 - 2.533 0.527 - 540 1 2 0 0.004 11 0 0 0 3.62E+05 1.88E+07 - - - 5.4464 1 221125_WJC_METTL3_EV_vs_WT_F03.26302.26302.3 3.40E-07 14/88 K.IMQSSSEVGYDAMAGDFVNMVEK.G "sp|P10809|CH60_HUMAN,tr|A0A7I2V2X6|A0A7I2V2X6_HUMAN,tr|A0A7I2YQK6|A0A7I2YQK6_HUMAN,tr|A0A7I2V599|A0A7I2V599_HUMAN" 4 2507.1018 0.73 40436 26302 3 2507.099215 836.7079 "60 kDa heat shock protein, mitochondrial OS=Homo sapiens OX=9606 GN=HSPD1 PE=1 SV=2" 3.92 3989.5 - 452194 - - - -1.0502 - 2.768 0.54 - 85.9 1 2 0 -0.0026 23 0 0 0 2.62E+06 3.61E+06 - - - 6.9482 1 221125_WJC_METTL3_EV_vs_WT_F03.26303.26303.3 7.18E-09 19/56 R.R[166.11]GVMLAVDAVIAELK[136.11].K "sp|P10809|CH60_HUMAN,tr|A0A7I2V2X6|A0A7I2V2X6_HUMAN,tr|A0A7I2V599|A0A7I2V599_HUMAN,tr|E7EXB4|E7EXB4_HUMAN,tr|A0A7I2YQ71|A0A7I2YQ71_HUMAN,tr|E7ESH4|E7ESH4_HUMAN,tr|A0A7I2V5M1|A0A7I2V5M1_HUMAN,tr|A0A7I2V5K3|A0A7I2V5K3_HUMAN,tr|A0A7I2V369|A0A7I2V369_HUMAN" 9 1601.9294 1.45 40437 26303 3 1601.928269 534.9837 "60 kDa heat shock protein, mitochondrial OS=Homo sapiens OX=9606 GN=HSPD1 PE=1 SV=2" 6.07 3989.6 - 412552 - - - -0.6867 - 3.568 0.611 - 569.7 1 2 0 -0.0011 15 0 0 0 2.11E+06 1.45E+06 - - - 8.6709 0.9995 221125_WJC_METTL3_EV_vs_WT_F03.26307.26307.3 0.00033 Nov-76 R.TYIVEETVGQYLSNINLQGK.A sp|Q5SWX8|ODR4_HUMAN 1 2268.1638 2.13 40440 26307 3 2268.170445 757.0619 Protein odr-4 homolog OS=Homo sapiens OX=9606 GN=ODR4 PE=1 SV=1 4.53 3990.1 - 362334 - - - 2.9394 - 2.182 0.394 - 125 1 2 0 0.0067 20 0 0 0 7.35E+06 3.45E+06 - - - 4.8237 1 221125_WJC_METTL3_EV_vs_WT_F03.26309.26309.3 2.05E-11 20/84 R.EADIDGDGQVNYEEFVQMMTAK.- "sp|P0DP25|CALM3_HUMAN,sp|P0DP23|CALM1_HUMAN,sp|P0DP24|CALM2_HUMAN,tr|Q96HY3|Q96HY3_HUMAN,tr|M0QZ52|M0QZ52_HUMAN,tr|E7EMB3|E7EMB3_HUMAN" 6 2489.0727 1.63 40441 26309 3 2489.077566 830.6982 Calmodulin-3 OS=Homo sapiens OX=9606 GN=CALM3 PE=1 SV=1 3.71 3990.5 - 1.23E+06 - - - 1.9726 - 3.865 0.712 - 615.1 1 2 0 0.0049 22 0 0 0 5.73E+06 3.51E+06 - - - 9.682 1 221125_WJC_METTL3_EV_vs_WT_F03.26311.26311.2 2.14E-12 21/36 R.SPNEEYTWEEDPLAGIIPR.T "sp|P52732|KIF11_HUMAN,tr|A0A7I2YQY4|A0A7I2YQY4_HUMAN,tr|A0A7I2V3A9|A0A7I2V3A9_HUMAN,tr|A0A7I2V3V3|A0A7I2V3V3_HUMAN" 4 2215.0433 8.67 40443 26311 2 2215.04429 1108.5289 Kinesin-like protein KIF11 OS=Homo sapiens OX=9606 GN=KIF11 PE=1 SV=2 3.91 3990.7 - 1.46E+06 - - - 0.4339 - 4.025 0.715 - 975.5 1 2 0 0.001 19 0 0 0 1.47E+07 1.69E+06 - - - 7.7453 0.9996 221125_WJC_METTL3_EV_vs_WT_F03.26315.26315.4 0.0245 14/162 K.ETETEVLLLEHDVPHQPFSQAVLSFLPK.M "sp|Q9Y2L1|RRP44_HUMAN,tr|F2Z2C0|F2Z2C0_HUMAN,tr|G3V1J5|G3V1J5_HUMAN" 3 3202.655 2.31 40447 26315 4 3202.661506 801.671 Exosome complex exonuclease RRP44 OS=Homo sapiens OX=9606 GN=DIS3 PE=1 SV=2 4.56 3991.2 - 613782 - - - 2.0218 - 2.603 0.365 - 64.8 1 2 0 0.0065 28 0 0 0 4.27E+06 1.85E+06 - - - 2.6982 0.9999 221125_WJC_METTL3_EV_vs_WT_F03.26318.26318.3 8.39E-05 Dec-56 R.RGVMLAVDAVIAELK.K "sp|P10809|CH60_HUMAN,tr|A0A7I2V2X6|A0A7I2V2X6_HUMAN,tr|A0A7I2V599|A0A7I2V599_HUMAN,tr|E7EXB4|E7EXB4_HUMAN,tr|A0A7I2YQ71|A0A7I2YQ71_HUMAN,tr|E7ESH4|E7ESH4_HUMAN,tr|A0A7I2V5M1|A0A7I2V5M1_HUMAN,tr|A0A7I2V5K3|A0A7I2V5K3_HUMAN,tr|A0A7I2V369|A0A7I2V369_HUMAN" 9 1583.9069 1.45 40450 26318 3 1583.90907 528.9762 "60 kDa heat shock protein, mitochondrial OS=Homo sapiens OX=9606 GN=HSPD1 PE=1 SV=2" 6.07 3991.6 - 408268 - - - 1.3707 - 2.615 0.465 - 216.9 1 2 0 0.0022 15 0 0 0 2.11E+06 1.45E+06 - - - 6.232 0.9959 221125_WJC_METTL3_EV_vs_WT_F03.26319.26319.2 2.04 12-May R.FSGVPDR.F "sp|A0A075B6R9|KVD24_HUMAN,sp|A0A0C4DH68|KV224_HUMAN,sp|A2NJV5|KV229_HUMAN,sp|A0A075B6S2|KVD29_HUMAN,sp|A0A0A0MRZ7|KVD26_HUMAN" 5 776.3817 28.29 40451 26319 2 776.381673 389.1981 Probable non-functional immunoglobulin kappa variable 2D-24 OS=Homo sapiens OX=9606 GN=IGKV2D-24 PE=1 SV=1 5.84 3991.7 - 242349 - - - -0.0386 - 1.218 0.214 - 76.3 1 2 0 0 7 0 0 0 3.72E+06 1.31E+05 - - - 1.2465 0.9987 221125_WJC_METTL3_EV_vs_WT_F03.26320.26320.2 0.0324 18-Sep K.FAAQELIEVK[136.11].R "sp|Q86U44|MTA70_HUMAN,tr|F5H6D8|F5H6D8_HUMAN,tr|H0YFV6|H0YFV6_HUMAN,tr|B4DTN4|B4DTN4_HUMAN" 4 1154.6427 0.001 40452 26320 2 1154.645117 578.3286 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 4.53 3991.9 - 237799 - - - 2.1149 - 1.87 0.299 - 189.2 1 2 0 0.0024 10 0 0 0 0.00E+00 3.13E+06 - - - 2.9958 0.9926 221125_WJC_METTL3_EV_vs_WT_F03.26322.26322.2 0.0551 Feb-42 R.EADIDGDGQVNYEEFVQMMTAK.- "sp|P0DP25|CALM3_HUMAN,sp|P0DP23|CALM1_HUMAN,sp|P0DP24|CALM2_HUMAN,tr|Q96HY3|Q96HY3_HUMAN,tr|M0QZ52|M0QZ52_HUMAN,tr|E7EMB3|E7EMB3_HUMAN" 6 2489.0727 -1 40454 26322 2 2489.070806 1245.5436 Calmodulin-3 OS=Homo sapiens OX=9606 GN=CALM3 PE=1 SV=1 3.71 3992.1 - 189845 - - - -0.7432 - 0.787 0.372 - 5.3 5 2 0 -0.0019 22 0 0 0 0.00E+00 0.00E+00 - - - 0.8869 0.9997 221125_WJC_METTL3_EV_vs_WT_F03.26326.26326.3 3.14E-05 17/68 K.ETDLLLDDSLVSIFGNRR.L sp|P30044|PRDX5_HUMAN 1 2062.0695 0.99 40456 26326 3 2062.07582 688.3638 "Peroxiredoxin-5, mitochondrial OS=Homo sapiens OX=9606 GN=PRDX5 PE=1 SV=4" 4.23 3992.6 - 1.32E+06 - - - 3.0726 - 2.344 0.446 - 273.6 1 2 0 0.0063 18 0 0 0 3.91E+06 3.95E+06 - - - 5.6319 1 221125_WJC_METTL3_EV_vs_WT_F03.26328.26328.3 1.25E-10 18/72 K.DQQEAALVDMVNDGVEDLR.C "sp|P09211|GSTP1_HUMAN,tr|A8MX94|A8MX94_HUMAN" 2 2115.9743 1.44 40458 26328 3 2115.980697 706.332 Glutathione S-transferase P OS=Homo sapiens OX=9606 GN=GSTP1 PE=1 SV=2 3.66 3992.9 - 1.27E+06 - - - 3.0407 - 3.624 0.651 - 458.7 1 2 0 0.0064 19 0 0 0 4.56E+06 3.16E+06 - - - 8.9595 1 221125_WJC_METTL3_EV_vs_WT_F03.26330.26330.3 7.72E-09 21/72 K.NVVHQLSVTLEDLYNGATR[166.11].K sp|P31689|DNJA1_HUMAN 1 2138.0996 0.58 40460 26330 3 2138.104966 713.7071 DnaJ homolog subfamily A member 1 OS=Homo sapiens OX=9606 GN=DNAJA1 PE=1 SV=2 5.32 3993.1 - 1.03E+06 - - - 2.5322 - 3.454 0.539 - 566.3 1 2 0 0.0054 19 0 0 0 3.17E+06 5.48E+06 - - - 7.5931 1 221125_WJC_METTL3_EV_vs_WT_F03.26331.26331.2 2.74E-08 17/30 K.AAGVNVEPFWPGLFAK.A sp|P05386|RLA1_HUMAN 1 1701.8879 1.46 40461 26331 2 1701.895247 851.9512 60S acidic ribosomal protein P1 OS=Homo sapiens OX=9606 GN=RPLP1 PE=1 SV=1 6.05 3993.3 - 813932 - - - 4.3299 - 3.258 0.566 - 729.6 1 2 0 0.0074 16 0 0 0 7.71E+06 5.27E+06 - - - 6.123 0.9995 221125_WJC_METTL3_EV_vs_WT_F03.26333.26333.4 0.00656 13/126 K.TLTAIAVILTNFHDGRPLPIER.V "sp|Q14527|HLTF_HUMAN,tr|A0A0C4DGA6|A0A0C4DGA6_HUMAN" 2 2446.3696 1.16 40463 26333 4 2446.37652 612.5997 Helicase-like transcription factor OS=Homo sapiens OX=9606 GN=HLTF PE=1 SV=2 6.42 3993.5 - 407240 - - - 2.8168 - 2.173 0.383 - 69.9 1 2 0 0.0069 22 0 0 0 1.30E+07 1.12E+07 - - - 2.8117 0.9976 221125_WJC_METTL3_EV_vs_WT_F03.26335.26335.3 0.0131 Jul-56 K.DQPPNSVEGLLNALR[166.11].Y sp|Q9NUQ9|CYRIB_HUMAN 1 1631.8507 0.89 40465 26335 3 1631.851699 544.9575 CYFIP-related Rac1 interactor B OS=Homo sapiens OX=9606 GN=CYRIB PE=1 SV=1 4.37 3993.8 - 139089 - - - 0.6404 - 1.454 0.287 - 62 1 2 0 0.001 15 0 0 0 4.91E+05 5.54E+05 - - - 2.7162 0.9923 221125_WJC_METTL3_EV_vs_WT_F03.26336.26336.2 0.00119 16-Jun R.YLDVSILGK[136.11].F sp|Q86U44|MTA70_HUMAN 1 1014.5841 0.57 40466 26336 2 1014.583796 508.2993 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 5.83 3993.9 - 84008.1 - - - -0.2977 - 1.196 0.168 - 79.8 1 2 0 -0.0003 9 0 0 0 4.85E+05 8.46E+05 - - - 0.7996 1 221125_WJC_METTL3_EV_vs_WT_F03.26339.26339.3 6.89E-13 21/64 K.TTQVPQFILDDFIQNDR.A sp|Q08211|DHX9_HUMAN 1 2049.0167 1 40467 26339 3 2049.02057 684.0128 ATP-dependent RNA helicase A OS=Homo sapiens OX=9606 GN=DHX9 PE=1 SV=4 3.93 3994.3 - 3.35E+06 - - - 1.879 - 3.495 0.632 - 820.5 1 2 0 0.0039 17 0 0 0 3.90E+07 3.89E+07 - - - 8.7464 1 221125_WJC_METTL3_EV_vs_WT_F03.26340.26340.3 4.43E-12 23/84 R.K[136.11]PLVIIAEDVDGEALSTLVLNR[166.11].L "sp|P10809|CH60_HUMAN,tr|A0A7I2V2X6|A0A7I2V2X6_HUMAN,tr|A0A7I2YQK6|A0A7I2YQK6_HUMAN,tr|A0A7I2V599|A0A7I2V599_HUMAN,tr|A0A7I2YQ71|A0A7I2YQ71_HUMAN,tr|A0A7I2V5M1|A0A7I2V5M1_HUMAN,tr|A0A7I2V5K3|A0A7I2V5K3_HUMAN" 7 2382.3489 1.06 40468 26340 3 2382.350863 795.1236 "60 kDa heat shock protein, mitochondrial OS=Homo sapiens OX=9606 GN=HSPD1 PE=1 SV=2" 4.32 3994.4 - 2.11E+06 - - - 0.8252 - 4.72 0.712 - 656.3 1 2 0 0.002 22 0 0 0 3.04E+07 2.88E+07 - - - 10.1566 1 221125_WJC_METTL3_EV_vs_WT_F03.26341.26341.2 5.56E-08 16/32 K.TTQVPQFILDDFIQNDR.A sp|Q08211|DHX9_HUMAN 1 2049.0167 0.78 40469 26341 2 2049.01996 1025.5156 ATP-dependent RNA helicase A OS=Homo sapiens OX=9606 GN=DHX9 PE=1 SV=4 3.93 3994.5 - 994471 - - - 1.5812 - 2.924 0.57 - 499.5 1 2 0 0.0032 17 0 0 0 1.51E+07 1.93E+07 - - - 5.8879 1 221125_WJC_METTL3_EV_vs_WT_F03.26350.26350.3 9.61E-08 17/64 K.ATENDIYNFFSPLNPVR.V "sp|P52597|HNRPF_HUMAN,sp|P31943|HNRH1_HUMAN,tr|H0YBD7|H0YBD7_HUMAN,tr|H0YB39|H0YB39_HUMAN,tr|H0YBG7|H0YBG7_HUMAN,tr|E9PCY7|E9PCY7_HUMAN,tr|G8JLB6|G8JLB6_HUMAN" 7 1995.969 1.68 40476 26350 3 1995.97302 666.3303 Heterogeneous nuclear ribonucleoprotein F OS=Homo sapiens OX=9606 GN=HNRNPF PE=1 SV=3 4.37 3995.7 - 1.15E+06 - - - 1.9935 - 3.064 0.562 - 284.5 1 2 0 0.004 17 0 0 0 1.50E+07 8.93E+06 - - - 7.6334 1 221125_WJC_METTL3_EV_vs_WT_F03.26351.26351.2 1.81E-08 20/32 K.TTQVPQFILDDFIQNDR[166.11].A sp|Q08211|DHX9_HUMAN 1 2059.025 0.78 40477 26351 2 2059.027566 1030.5198 ATP-dependent RNA helicase A OS=Homo sapiens OX=9606 GN=DHX9 PE=1 SV=4 3.93 3995.8 - 2.23E+06 - - - 1.2511 - 3.16 0.56 - 1109 1 2 0 0.0026 17 0 0 0 1.51E+07 1.93E+07 - - - 6.0051 1 221125_WJC_METTL3_EV_vs_WT_F03.26352.26352.3 2.19E-10 23/76 K.ELHSEFSEVMNEIWASDQIR[166.11].S "sp|P40939|ECHA_HUMAN,tr|A0A2R8YG21|A0A2R8YG21_HUMAN,tr|A0A2R8Y688|A0A2R8Y688_HUMAN,tr|H0YFD6|H0YFD6_HUMAN,tr|A0A2R8Y4F5|A0A2R8Y4F5_HUMAN" 5 2429.1197 0.83 40478 26352 3 2429.119493 810.7138 "Trifunctional enzyme subunit alpha, mitochondrial OS=Homo sapiens OX=9606 GN=HADHA PE=1 SV=2" 4.25 3995.9 - 1.34E+06 - - - -0.0832 - 4.516 0.621 - 530 1 2 0 -0.0002 20 0 0 0 4.02E+06 4.83E+06 - - - 9.121 1 221125_WJC_METTL3_EV_vs_WT_F03.26353.26353.3 0.000279 16/64 K.ATENDIYNFFSPLNPVR[166.11].V "sp|P52597|HNRPF_HUMAN,sp|P31943|HNRH1_HUMAN,tr|H0YBD7|H0YBD7_HUMAN,tr|H0YB39|H0YB39_HUMAN,tr|H0YBG7|H0YBG7_HUMAN,tr|E9PCY7|E9PCY7_HUMAN,tr|G8JLB6|G8JLB6_HUMAN" 7 2005.9773 1.65 40479 26353 3 2005.979193 669.6664 Heterogeneous nuclear ribonucleoprotein F OS=Homo sapiens OX=9606 GN=HNRNPF PE=1 SV=3 4.37 3996 - 1.18E+06 - - - 0.9382 - 2.912 0.533 - 273.4 1 2 0 0.0019 17 0 0 0 1.47E+07 8.93E+06 - - - 7.1821 0.9707 221125_WJC_METTL3_EV_vs_WT_F03.26355.26355.3 1.03E-05 17/80 R.TLDNLTIVTTDLEQEVEGMRK.E "sp|Q9C075|K1C23_HUMAN,tr|J3QR55|J3QR55_HUMAN" 2 2404.2156 -1 40481 26355 3 2405.204749 802.4125 "Keratin, type I cytoskeletal 23 OS=Homo sapiens OX=9606 GN=KRT23 PE=1 SV=2" 4.18 3996.2 - 699938 - - - 411.4411 - 3.185 0.474 - 215.1 1 2 0 0.9892 21 0 0 0 0.00E+00 0.00E+00 - - - 6.328 0.9997 221125_WJC_METTL3_EV_vs_WT_F03.26361.26361.3 0.00283 Nov-56 K.VSQEILELLNTTTAK[136.11].E "sp|Q86U44|MTA70_HUMAN,tr|H0YFV6|H0YFV6_HUMAN" 2 1666.9233 0.04 40487 26361 3 1666.925537 556.6484 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 4.53 3997 - 255673 - - - 1.3618 - 2.031 0.374 - 186.7 1 2 0 0.0023 15 0 0 0 9.57E+04 2.49E+06 - - - 4.5579 1 221125_WJC_METTL3_EV_vs_WT_F03.26364.26364.3 1.83E-06 Oct-76 K.ELHSEFSEVMNEIWASDQIR.S "sp|P40939|ECHA_HUMAN,tr|A0A2R8YG21|A0A2R8YG21_HUMAN,tr|A0A2R8Y688|A0A2R8Y688_HUMAN,tr|H0YFD6|H0YFD6_HUMAN,tr|A0A2R8Y4F5|A0A2R8Y4F5_HUMAN" 5 2419.1114 0.83 40489 26364 3 2419.11402 807.3778 "Trifunctional enzyme subunit alpha, mitochondrial OS=Homo sapiens OX=9606 GN=HADHA PE=1 SV=2" 4.25 3997.4 - 258894 - - - 1.0727 - 2.738 0.579 - 83.3 1 2 0 0.0026 20 0 0 0 4.02E+06 4.83E+06 - - - 7.4381 1 221125_WJC_METTL3_EV_vs_WT_F03.26365.26365.4 2.37E-07 16/126 R.KPLVIIAEDVDGEALSTLVLNR.L "sp|P10809|CH60_HUMAN,tr|A0A7I2V2X6|A0A7I2V2X6_HUMAN,tr|A0A7I2YQK6|A0A7I2YQK6_HUMAN,tr|A0A7I2V599|A0A7I2V599_HUMAN,tr|A0A7I2YQ71|A0A7I2YQ71_HUMAN,tr|A0A7I2V5M1|A0A7I2V5M1_HUMAN,tr|A0A7I2V5K3|A0A7I2V5K3_HUMAN" 7 2364.3264 1.38 40490 26365 4 2364.326363 592.0889 "60 kDa heat shock protein, mitochondrial OS=Homo sapiens OX=9606 GN=HSPD1 PE=1 SV=2" 4.32 3997.5 - 463061 - - - -0.0271 - 3.28 0.53 - 196.8 1 2 0 -0.0001 22 0 0 0 2.56E+06 1.85E+06 - - - 4.2278 1 221125_WJC_METTL3_EV_vs_WT_F03.26366.26366.3 6.74E-11 23/100 R.EIQLWFQSSELVSWADGGQHSSIHPA.- "sp|O00746|NDKM_HUMAN,tr|Q4TT34|Q4TT34_HUMAN,tr|A0A087WVT9|A0A087WVT9_HUMAN" 3 2908.378 - 40491 26366 3 2908.374928 970.4666 "Nucleoside diphosphate kinase, mitochondrial OS=Homo sapiens OX=9606 GN=NME4 PE=1 SV=1" 4.63 3997.5 - 5.56E+06 - - - -1.0635 - 3.869 0.564 - 430.7 1 2 0 -0.0031 26 0 0 0 - - - - - 7.9399 1 221125_WJC_METTL3_EV_vs_WT_F03.26368.26368.4 7.95E-07 32/198 R.GPPPSGIATLVSGIAGGAIPGQAPGSVPGPGLVK.D "tr|A0A804CDA6|A0A804CDA6_HUMAN,tr|E7EX90|E7EX90_HUMAN" 2 2975.6444 2.82 40493 26368 4 2975.648874 744.9184 Dynactin subunit 1 OS=Homo sapiens OX=9606 GN=DCTN1 PE=4 SV=1 8.75 3997.8 - 1.27E+06 - - - 1.5012 - 4.455 0.563 - 361.1 1 2 0 0.0045 34 0 0 0 3.95E+07 1.40E+07 - - - 4.5706 1 221125_WJC_METTL3_EV_vs_WT_F03.26369.26369.3 8.66E-12 27/132 R.GPPPSGIATLVSGIAGGAIPGQAPGSVPGPGLVK.D "tr|A0A804CDA6|A0A804CDA6_HUMAN,tr|E7EX90|E7EX90_HUMAN" 2 2975.6444 2.75 40494 26369 3 2975.643428 992.8887 Dynactin subunit 1 OS=Homo sapiens OX=9606 GN=DCTN1 PE=4 SV=1 8.75 3997.9 - 1.09E+06 - - - -0.329 - 3.888 0.651 - 369.9 1 2 0 -0.001 34 0 0 0 4.05E+07 1.47E+07 - - - 8.9218 0.9998 221125_WJC_METTL3_EV_vs_WT_F03.26370.26370.3 5.52E-09 20/84 R.EISESTPVEEVEALFKGDNLPK.F sp|Q92615|LAR4B_HUMAN 1 2430.2166 0.84 40495 26370 3 2430.223841 811.0795 La-related protein 4B OS=Homo sapiens OX=9606 GN=LARP4B PE=1 SV=3 4.14 3998 - 898254 - - - 2.9787 - 3.532 0.581 - 333.7 1 2 1 0.0072 22 0 0 0 2.32E+07 2.76E+07 - - - 8.0072 0.9999 221125_WJC_METTL3_EV_vs_WT_F03.26373.26373.3 1.09E-05 11/124 R.IGPEPTTDSFIAVMYGETEGSTPGNALVVDPK[136.11].K sp|Q9H223|EHD4_HUMAN 1 3299.5999 -1 40498 26373 3 3299.59931 1100.8739 EH domain-containing protein 4 OS=Homo sapiens OX=9606 GN=EHD4 PE=1 SV=1 3.83 3998.4 - 374300 - - - -0.1761 - 2.445 0.474 - 70.2 1 2 0 -0.0006 32 0 0 0 0.00E+00 0.00E+00 - - - 5.8813 0.9998 221125_WJC_METTL3_EV_vs_WT_F03.26374.26374.4 1.26E-06 16/126 R.K[136.11]PLVIIAEDVDGEALSTLVLNR[166.11].L "sp|P10809|CH60_HUMAN,tr|A0A7I2V2X6|A0A7I2V2X6_HUMAN,tr|A0A7I2YQK6|A0A7I2YQK6_HUMAN,tr|A0A7I2V599|A0A7I2V599_HUMAN,tr|A0A7I2YQ71|A0A7I2YQ71_HUMAN,tr|A0A7I2V5M1|A0A7I2V5M1_HUMAN,tr|A0A7I2V5K3|A0A7I2V5K3_HUMAN" 7 2382.3489 9.94 40499 26374 4 2382.357676 596.5945 "60 kDa heat shock protein, mitochondrial OS=Homo sapiens OX=9606 GN=HSPD1 PE=1 SV=2" 4.32 3998.6 - 285957 - - - 3.685 - 3.019 0.504 - 228.6 1 2 0 0.0088 22 0 0 0 2.42E+07 2.43E+06 - - - 3.9719 1 221125_WJC_METTL3_EV_vs_WT_F03.26379.26379.3 1.63E-15 25/116 K.DMAIATGGAVFGEEGLTLNLEDVQPHDLGK.V "sp|P10809|CH60_HUMAN,tr|A0A7I2V2X6|A0A7I2V2X6_HUMAN,tr|A0A7I2YQK6|A0A7I2YQK6_HUMAN,tr|A0A7I2V599|A0A7I2V599_HUMAN" 4 3096.5074 1.39 40503 26379 3 3096.509846 1033.1764 "60 kDa heat shock protein, mitochondrial OS=Homo sapiens OX=9606 GN=HSPD1 PE=1 SV=2" 4.01 3999.2 - 3.52E+06 - - - 0.7961 - 4.808 0.717 - 427.2 1 2 0 0.0025 30 0 0 0 3.22E+07 2.32E+07 - - - 10.1458 1 221125_WJC_METTL3_EV_vs_WT_F03.26381.26381.3 6.58E-13 22/104 K.EIAEAYLGYPVTNAVITVPAYFNDSQR.Q "sp|P0DMV8|HS71A_HUMAN,sp|P0DMV9|HS71B_HUMAN,tr|A0A0G2JIW1|A0A0G2JIW1_HUMAN" 3 3000.4869 0.14 40504 26381 3 3000.490598 1001.1696 Heat shock 70 kDa protein 1A OS=Homo sapiens OX=9606 GN=HSPA1A PE=1 SV=1 4.14 3999.4 - 2.39E+06 - - - 1.2315 - 4.434 0.697 - 183.9 1 2 0 0.0037 27 0 0 0 2.35E+07 1.64E+08 - - - 9.7362 1 221125_WJC_METTL3_EV_vs_WT_F03.26382.26382.4 4.19E-08 26/198 R.GPPPSGIATLVSGIAGGAIPGQAPGSVPGPGLVK[136.11].D "tr|A0A804CDA6|A0A804CDA6_HUMAN,tr|E7EX90|E7EX90_HUMAN" 2 2983.6586 2.82 40505 26382 4 2983.662958 746.9219 Dynactin subunit 1 OS=Homo sapiens OX=9606 GN=DCTN1 PE=4 SV=1 8.75 3999.5 - 1.53E+06 - - - 1.4583 - 3.87 0.609 - 193.4 1 2 0 0.0044 34 0 0 0 3.95E+07 1.40E+07 - - - 4.9291 1 221125_WJC_METTL3_EV_vs_WT_F03.26384.26384.3 1.26E-13 29/84 R.EISESTPVEEVEALFK[136.11]GDNLPK[136.11].F sp|Q92615|LAR4B_HUMAN 1 2446.245 0.84 40507 26384 3 2446.248973 816.4223 La-related protein 4B OS=Homo sapiens OX=9606 GN=LARP4B PE=1 SV=3 4.14 3999.7 - 1.92E+06 - - - 1.6233 - 3.987 0.66 - 744.5 1 2 1 0.004 22 0 0 0 2.33E+07 2.76E+07 - - - 9.1762 1 221125_WJC_METTL3_EV_vs_WT_F03.26386.26386.3 1.29E-10 32/132 R.GPPPSGIATLVSGIAGGAIPGQAPGSVPGPGLVK[136.11].D "tr|A0A804CDA6|A0A804CDA6_HUMAN,tr|E7EX90|E7EX90_HUMAN" 2 2983.6586 2.75 40509 26386 3 2983.662997 995.5601 Dynactin subunit 1 OS=Homo sapiens OX=9606 GN=DCTN1 PE=4 SV=1 8.75 3999.9 - 920841 - - - 1.4713 - 4.151 0.69 - 543.9 1 2 0 0.0044 34 0 0 0 4.05E+07 1.47E+07 - - - 9.5062 1 221125_WJC_METTL3_EV_vs_WT_F03.26388.26388.4 5.28E-14 22/144 K.VEESGEHVILGTGELYLDC[160.03]VMHDLR.K sp|Q15029|U5S1_HUMAN 1 2870.3579 -1 40511 26388 4 2870.3609 718.5967 116 kDa U5 small nuclear ribonucleoprotein component OS=Homo sapiens OX=9606 GN=EFTUD2 PE=1 SV=1 4.35 4000.2 - 732497 - - - 1.0521 - 4.422 0.663 - 318.4 1 2 0 0.003 25 0 0 0 0.00E+00 0.00E+00 - - - 5.4688 0.9999 221125_WJC_METTL3_EV_vs_WT_F03.26389.26389.3 2.33E-06 13/64 R.ATENDIANFFSPLNPIR.V sp|P31942|HNRH3_HUMAN 1 1917.9585 3.25 40512 26389 3 1917.963273 640.3268 Heterogeneous nuclear ribonucleoprotein H3 OS=Homo sapiens OX=9606 GN=HNRNPH3 PE=1 SV=2 4.37 4000.3 - 687282 - - - 2.5006 - 2.484 0.469 - 182.9 1 2 0 0.0048 17 0 0 0 2.30E+06 7.08E+05 - - - 6.0662 0.9991 221125_WJC_METTL3_EV_vs_WT_F03.26390.26390.4 0.00294 11/108 K.FATLAELVQYYMEHHGQLK[136.11].E "sp|Q06124|PTN11_HUMAN,tr|A0A1W2PPU4|A0A1W2PPU4_HUMAN" 2 2285.1394 0.62 40513 26390 4 2285.143171 572.2921 Tyrosine-protein phosphatase non-receptor type 11 OS=Homo sapiens OX=9606 GN=PTPN11 PE=1 SV=3 6 4000.5 - 463664 - - - 1.6397 - 2.08 0.316 - 60.2 1 2 0 0.0037 19 0 0 0 6.11E+05 9.78E+05 - - - 2.2232 0.9998 221125_WJC_METTL3_EV_vs_WT_F03.26391.26391.2 1.87E-06 Oct-32 R.ATENDIANFFSPLNPIR.V sp|P31942|HNRH3_HUMAN 1 1917.9585 -1 40514 26391 2 1917.96146 959.9865 Heterogeneous nuclear ribonucleoprotein H3 OS=Homo sapiens OX=9606 GN=HNRNPH3 PE=1 SV=2 4.37 4000.6 - 393802 - - - 1.5553 - 2.532 0.553 - 255.2 1 2 0 0.003 17 0 0 0 0.00E+00 0.00E+00 - - - 5.4085 1 221125_WJC_METTL3_EV_vs_WT_F03.26393.26393.2 4.15E-21 23/52 K.EIAEAYLGYPVTNAVITVPAYFNDSQR[166.11].Q "sp|P0DMV8|HS71A_HUMAN,sp|P0DMV9|HS71B_HUMAN,tr|A0A0G2JIW1|A0A0G2JIW1_HUMAN" 3 3010.4952 0.06 40516 26393 2 3012.505447 1506.2549 Heat shock 70 kDa protein 1A OS=Homo sapiens OX=9606 GN=HSPA1A PE=1 SV=1 4.14 4000.9 - 346404 - - - 667.7553 - 4.937 0.78 - 600.5 1 2 0 2.0103 27 0 0 0 3.56E+05 6.09E+06 - - - 8.0966 0.9999 221125_WJC_METTL3_EV_vs_WT_F03.26395.26395.4 0.0497 15/138 R.ILGGVISAISEAAAQYNPEPPPPR.T "sp|P04632|CPNS1_HUMAN,tr|A0A075B7C0|A0A075B7C0_HUMAN,tr|A0A0C4DGQ5|A0A0C4DGQ5_HUMAN,tr|K7ELJ7|K7ELJ7_HUMAN,tr|S4R3F9|S4R3F9_HUMAN,tr|K7EIV0|K7EIV0_HUMAN,tr|K7EM73|K7EM73_HUMAN" 7 2446.2856 1.16 40518 26395 4 2446.282324 612.5787 Calpain small subunit 1 OS=Homo sapiens OX=9606 GN=CAPNS1 PE=1 SV=1 4.53 4001.1 - 244478 - - - -1.3494 - 2.794 0.409 - 97 1 2 0 -0.0033 24 0 0 0 2.33E+06 2.01E+06 - - - 3.1148 1 221125_WJC_METTL3_EV_vs_WT_F03.26399.26399.3 9.99E-11 24/104 K.EIAEAYLGYPVTNAVITVPAYFNDSQR[166.11].Q "sp|P0DMV8|HS71A_HUMAN,sp|P0DMV9|HS71B_HUMAN,tr|A0A0G2JIW1|A0A0G2JIW1_HUMAN" 3 3010.4952 0.14 40521 26399 3 3010.496573 1004.5057 Heat shock 70 kDa protein 1A OS=Homo sapiens OX=9606 GN=HSPA1A PE=1 SV=1 4.14 4001.7 - 2.32E+07 - - - 0.465 - 4.76 0.638 - 289.9 1 2 0 0.0014 27 0 0 0 2.35E+07 1.64E+08 - - - 9.2422 1 221125_WJC_METTL3_EV_vs_WT_F03.26402.26402.4 9.46E-14 20/150 R.DLDELSRYPEDKITPENLPQILLQLK.R "sp|P43243|MATR3_HUMAN,tr|A8MXP9|A8MXP9_HUMAN,tr|D6R991|D6R991_HUMAN,tr|A0A0R4J2E8|A0A0R4J2E8_HUMAN,tr|D6REM6|D6REM6_HUMAN" 5 3079.6441 1.44 40523 26402 4 3079.647519 770.9183 Matrin-3 OS=Homo sapiens OX=9606 GN=MATR3 PE=1 SV=2 4.3 4001.9 - 3.47E+06 - - - 1.0998 - 3.547 0.709 - 211 1 2 2 0.0034 26 0 0 0 5.99E+07 4.16E+07 - - - 5.7956 1 221125_WJC_METTL3_EV_vs_WT_F03.26403.26403.4 3.01E-11 30/222 R.LPEEWSQWLGGSSWPGYVRPLPPAAIESPAVAAPAYSR.A "sp|P04792|HSPB1_HUMAN,tr|A0A6Q8PGY2|A0A6Q8PGY2_HUMAN,tr|A0A6Q8PHJ6|A0A6Q8PHJ6_HUMAN,tr|A0A6Q8PHA6|A0A6Q8PHA6_HUMAN,tr|A0A6Q8PF43|A0A6Q8PF43_HUMAN,tr|A0A6Q8PFK8|A0A6Q8PFK8_HUMAN,tr|A0A6Q8PGK1|A0A6Q8PGK1_HUMAN,tr|A0A6Q8PH65|A0A6Q8PH65_HUMAN,tr|A0A6Q8PFE7|A0A6Q8PFE7_HUMAN" 9 4092.0534 2.1 40524 26403 4 4092.057754 1024.0206 Heat shock protein beta-1 OS=Homo sapiens OX=9606 GN=HSPB1 PE=1 SV=2 4.79 4002.1 - 2.04E+06 - - - 1.0672 - 4.33 0.617 - 353.5 1 2 0 0.0044 38 0 0 0 9.00E+06 4.29E+06 - - - 5.0225 1 221125_WJC_METTL3_EV_vs_WT_F03.26404.26404.3 4.03E-09 30/100 R.SESGGLGVSMVEYVLSSSPADK[136.11]LDSR[166.11].F "sp|Q8TB72|PUM2_HUMAN,tr|C9JW01|C9JW01_HUMAN" 2 2687.3079 1.05 40525 26404 3 2687.309492 896.7766 Pumilio homolog 2 OS=Homo sapiens OX=9606 GN=PUM2 PE=1 SV=2 4.32 4002.2 - 1.78E+06 - - - 0.5939 - 4.953 0.648 - 831.2 1 2 1 0.0016 26 0 0 0 8.53E+06 8.13E+06 - - - 9.4451 0.9957 221125_WJC_METTL3_EV_vs_WT_F03.26406.26406.3 3.00E-06 Oct-68 K.LSSSIIHEIDSILGNKPY.S "sp|Q13303|KCAB2_HUMAN,tr|A0A5F9UN28|A0A5F9UN28_HUMAN,tr|A0A590UJB6|A0A590UJB6_HUMAN" 3 1985.047 1 40527 26406 3 1985.047848 662.6896 Voltage-gated potassium channel subunit beta-2 OS=Homo sapiens OX=9606 GN=KCNAB2 PE=1 SV=2 5.32 4002.4 - 1.19E+06 - - - 0.4489 - 2.46 0.48 - 104.2 1 1 0 0.0009 18 0 0 0 4.55E+06 4.53E+06 - - - 6.1328 1 221125_WJC_METTL3_EV_vs_WT_F03.26410.26410.3 1.81E-06 14/60 K.ELNAR[166.11]PLEVFMC[160.03]SVLK[136.11].R "sp|Q9Y6B6|SAR1B_HUMAN,tr|D6R9R5|D6R9R5_HUMAN,tr|Q9H029|Q9H029_HUMAN" 3 1923.0077 2.44 40531 26410 3 1923.006288 642.0098 GTP-binding protein SAR1b OS=Homo sapiens OX=9606 GN=SAR1B PE=1 SV=1 6.23 4002.9 - 198255 - - - -0.7322 - 2.485 0.553 - 301.9 1 2 0 -0.0014 16 0 0 0 3.51E+06 1.44E+06 - - - 7.0406 1 221125_WJC_METTL3_EV_vs_WT_F03.26413.26413.4 3.46E-09 16/150 R.DLDELSR[166.11]YPEDK[136.11]ITPENLPQILLQLK[136.11].R "sp|P43243|MATR3_HUMAN,tr|A8MXP9|A8MXP9_HUMAN,tr|D6R991|D6R991_HUMAN,tr|A0A0R4J2E8|A0A0R4J2E8_HUMAN,tr|D6REM6|D6REM6_HUMAN" 5 3105.6808 1.44 40532 26413 4 3105.675516 777.4275 Matrin-3 OS=Homo sapiens OX=9606 GN=MATR3 PE=1 SV=2 4.3 4003.3 - 3.95E+06 - - - -1.702 - 2.859 0.666 - 115.1 1 2 2 -0.0053 26 0 0 0 5.99E+07 4.16E+07 - - - 5.3528 1 221125_WJC_METTL3_EV_vs_WT_F03.26414.26414.4 7.17E-16 40/186 K.PVTTPEEIAQVATISANGDKEIGNIISDAMKK.V "sp|P10809|CH60_HUMAN,tr|A0A7I2V599|A0A7I2V599_HUMAN,tr|E7EXB4|E7EXB4_HUMAN,tr|A0A7I2YQ71|A0A7I2YQ71_HUMAN,tr|E7ESH4|E7ESH4_HUMAN,tr|A0A7I2V5M1|A0A7I2V5M1_HUMAN,tr|A0A7I2V5K3|A0A7I2V5K3_HUMAN,tr|A0A7I2V369|A0A7I2V369_HUMAN" 8 3339.7232 1.75 40533 26414 4 3339.717778 835.9381 "60 kDa heat shock protein, mitochondrial OS=Homo sapiens OX=9606 GN=HSPD1 PE=1 SV=2" 4.51 4003.4 - 3.66E+06 - - - -1.6196 - 6.869 0.627 - 1418.2 1 1 1 -0.0054 32 0 0 0 1.77E+07 1.01E+07 - - - 5.2637 1 221125_WJC_METTL3_EV_vs_WT_F03.26415.26415.4 1.28E-10 37/186 K.PVTTPEEIAQVATISANGDK[136.11]EIGNIISDAMK[136.11]K[136.11].V "sp|P10809|CH60_HUMAN,tr|A0A7I2V599|A0A7I2V599_HUMAN,tr|E7EXB4|E7EXB4_HUMAN,tr|A0A7I2YQ71|A0A7I2YQ71_HUMAN,tr|E7ESH4|E7ESH4_HUMAN,tr|A0A7I2V5M1|A0A7I2V5M1_HUMAN,tr|A0A7I2V5K3|A0A7I2V5K3_HUMAN,tr|A0A7I2V369|A0A7I2V369_HUMAN" 8 3363.7658 1.75 40534 26415 4 3363.759655 841.9487 "60 kDa heat shock protein, mitochondrial OS=Homo sapiens OX=9606 GN=HSPD1 PE=1 SV=2" 4.51 4003.5 - 2.30E+06 - - - -1.823 - 6.499 0.649 - 1011.2 1 1 1 -0.0061 32 0 0 0 1.77E+07 1.01E+07 - - - 5.4383 1 221125_WJC_METTL3_EV_vs_WT_F03.26418.26418.3 1.73E-07 21/108 K.GAAVESIPVFGALC[160.03]SSSSLHQTLEALAR.D sp|Q9BUK6|MSTO1_HUMAN 1 2870.4596 1.34 40537 26418 3 2870.455572 957.8272 Protein misato homolog 1 OS=Homo sapiens OX=9606 GN=MSTO1 PE=1 SV=1 5.4 4003.9 - 829423 - - - -1.4182 - 4.362 0.608 - 293.2 1 2 0 -0.0041 28 0 0 0 7.36E+06 5.49E+06 - - - 8.7062 1 221125_WJC_METTL3_EV_vs_WT_F03.26419.26419.2 4.30E-11 14/44 K.SINPDEAVAYGAAVQAAILSGDK[136.11].S "sp|P11142|HSP7C_HUMAN,tr|E9PNE6|E9PNE6_HUMAN,tr|A8K7Q2|A8K7Q2_HUMAN,tr|E9PKE3|E9PKE3_HUMAN" 4 2267.1525 0.33 40538 26419 2 2267.145559 1134.5835 Heat shock cognate 71 kDa protein OS=Homo sapiens OX=9606 GN=HSPA8 PE=1 SV=1 4.03 4004 - 642754 - - - -3.058 - 3.005 0.575 - 456.8 1 2 0 -0.0069 23 0 0 0 9.13E+05 2.73E+06 - - - 5.9909 1 221125_WJC_METTL3_EV_vs_WT_F03.26425.26425.3 3.86E-11 26/84 R.TLTAVHDAILEDLVFPSEIVGK.R "sp|P62081|RS7_HUMAN,tr|B5MCP9|B5MCP9_HUMAN,tr|A0A2R8Y623|A0A2R8Y623_HUMAN" 3 2366.2733 0.85 40542 26425 3 2366.264828 789.7651 40S ribosomal protein S7 OS=Homo sapiens OX=9606 GN=RPS7 PE=1 SV=1 4.31 4004.8 - 2.43E+06 - - - -3.5926 - 3.751 0.631 - 891.9 1 2 0 -0.0085 22 0 0 0 1.80E+07 2.11E+07 - - - 8.707 1 221125_WJC_METTL3_EV_vs_WT_F03.26426.26426.4 2.91E-13 27/138 R.RDELLAQHAAGALGLPDLVAVLTR.V "sp|P58107|EPIPL_HUMAN,sp|P58107|EPIPL_HUMAN,sp|P58107|EPIPL_HUMAN,sp|P58107|EPIPL_HUMAN,sp|P58107|EPIPL_HUMAN,tr|A0A075B730|A0A075B730_HUMAN,tr|A0A075B730|A0A075B730_HUMAN,tr|A0A075B730|A0A075B730_HUMAN,tr|A0A075B730|A0A075B730_HUMAN,tr|A0A075B730|A0A075B730_HUMAN" 10 2498.3969 1.47 40543 26426 4 2498.394096 625.6065 Epiplakin OS=Homo sapiens OX=9606 GN=EPPK1 PE=1 SV=3 5.38 4004.9 - 1.80E+06 - - - -1.1247 - 4.586 0.699 - 570.1 1 2 0 -0.0028 24 0 0 0 1.72E+07 1.17E+07 - - - 5.7982 1 221125_WJC_METTL3_EV_vs_WT_F03.26427.26427.4 9.16E-16 23/138 R.R[166.11]DELLAQHAAGALGLPDLVAVLTR[166.11].V "sp|P58107|EPIPL_HUMAN,sp|P58107|EPIPL_HUMAN,sp|P58107|EPIPL_HUMAN,sp|P58107|EPIPL_HUMAN,sp|P58107|EPIPL_HUMAN,tr|A0A075B730|A0A075B730_HUMAN,tr|A0A075B730|A0A075B730_HUMAN,tr|A0A075B730|A0A075B730_HUMAN,tr|A0A075B730|A0A075B730_HUMAN,tr|A0A075B730|A0A075B730_HUMAN" 10 2518.4134 1.47 40544 26427 4 2518.405113 630.6106 Epiplakin OS=Homo sapiens OX=9606 GN=EPPK1 PE=1 SV=3 5.38 4005 - 1.50E+06 - - - -3.3088 - 4.456 0.687 - 394 1 2 0 -0.0083 24 0 0 0 1.72E+07 1.17E+07 - - - 5.6829 0.9999 221125_WJC_METTL3_EV_vs_WT_F03.26433.26433.4 1.81E-07 17/108 K.YGIIC[160.03]MEDLIHEIYTVGK[136.11]R[166.11].F "sp|P18124|RL7_HUMAN,tr|A8MUD9|A8MUD9_HUMAN" 2 2327.1773 0.87 40548 26433 4 2327.170916 582.8016 60S ribosomal protein L7 OS=Homo sapiens OX=9606 GN=RPL7 PE=1 SV=1 5.45 4005.8 - 2.43E+06 - - - -2.7346 - 2.991 0.535 - 197.9 1 2 0 -0.0064 19 0 0 0 1.03E+07 1.18E+07 - - - 4.2515 1 221125_WJC_METTL3_EV_vs_WT_F03.26434.26434.3 1.10E-12 25/84 K.TDQVIQSLIALVNDPQPEHPLR.A "sp|A0A1B0GUS4|UB2L5_HUMAN,sp|P68036|UB2L3_HUMAN" 2 2482.318 1.87 40549 26434 3 2482.310813 828.4466 Ubiquitin-conjugating enzyme E2 L5 OS=Homo sapiens OX=9606 GN=UBE2L5 PE=2 SV=1 4.53 4005.9 - 2.88E+06 - - - -2.89 - 4.165 0.631 - 421.9 1 2 0 -0.0072 22 0 0 0 8.73E+06 4.66E+06 - - - 8.9555 0.9998 221125_WJC_METTL3_EV_vs_WT_F03.26436.26436.3 1.67E-09 23/104 K.GNFTLPEVAEC[160.03]FDEITYVELQK[136.11]EEAQK[136.11].L "sp|Q00839|HNRPU_HUMAN,tr|A0A1W2PQL0|A0A1W2PQL0_HUMAN,tr|A0A1W2PPL4|A0A1W2PPL4_HUMAN,tr|Q5RI18|Q5RI18_HUMAN,tr|A0A1W2PP35|A0A1W2PP35_HUMAN,tr|A0A1W2PPS1|A0A1W2PPS1_HUMAN,tr|A0A1W2PPH7|A0A1W2PPH7_HUMAN,tr|A0A1W2PQD4|A0A1W2PQD4_HUMAN,tr|A0A1W2PP34|A0A1W2PP34_HUMAN,tr|A0A1X7SBS1|A0A1X7SBS1_HUMAN" 10 3202.5351 -1 40551 26436 3 3202.524401 1068.519 Heterogeneous nuclear ribonucleoprotein U OS=Homo sapiens OX=9606 GN=HNRNPU PE=1 SV=6 4.06 4006.1 - 2.30E+06 - - - -3.3445 - 3.735 0.594 - 271.3 1 2 1 -0.0107 27 0 0 0 0.00E+00 0.00E+00 - - - 8.1912 1 221125_WJC_METTL3_EV_vs_WT_F03.26437.26437.3 3.90E-08 16/64 K.QPNSGIENFLASLNISK.E "sp|Q8IZH2|XRN1_HUMAN,tr|H7C5E4|H7C5E4_HUMAN,tr|H7C583|H7C583_HUMAN" 3 1830.9476 1.23 40552 26437 3 1830.943392 611.3231 5'-3' exoribonuclease 1 OS=Homo sapiens OX=9606 GN=XRN1 PE=1 SV=1 6 4006.2 - 1.92E+06 - - - -2.2862 - 3.08 0.528 - 328.7 1 2 0 -0.0042 17 0 0 0 8.02E+06 6.53E+06 - - - 7.2674 1 221125_WJC_METTL3_EV_vs_WT_F03.26438.26438.2 1.77E-10 16/32 K.QPNSGIENFLASLNISK.E "sp|Q8IZH2|XRN1_HUMAN,tr|H7C5E4|H7C5E4_HUMAN,tr|H7C583|H7C583_HUMAN" 3 1830.9476 -1 40553 26438 2 1830.945478 916.4811 5'-3' exoribonuclease 1 OS=Homo sapiens OX=9606 GN=XRN1 PE=1 SV=1 6 4006.3 - 1.92E+06 - - - -1.1469 - 3.316 0.628 - 791.3 1 2 0 -0.0021 17 0 0 0 0.00E+00 0.00E+00 - - - 6.626 0.9999 221125_WJC_METTL3_EV_vs_WT_F03.26439.26439.3 0.211 17/48 R.DALSDLALHFLNK[136.11].M sp|P50991|TCPD_HUMAN 1 1463.7864 0.61 40554 26439 3 1463.784153 488.9361 T-complex protein 1 subunit delta OS=Homo sapiens OX=9606 GN=CCT4 PE=1 SV=4 5.21 4006.5 - 1.67E+06 - - - -1.5207 - 3.27 0.396 - 360.6 1 2 0 -0.0022 13 0 0 0 4.77E+06 7.82E+06 - - - 6.1667 0.9994 221125_WJC_METTL3_EV_vs_WT_F03.26440.26440.3 0.000582 14/72 R.ELAKVEEEIQTLSQVLAAK.E "sp|P55327|TPD52_HUMAN,tr|H0YC44|H0YC44_HUMAN,tr|E5RFR7|E5RFR7_HUMAN,tr|H0YC42|H0YC42_HUMAN" 4 2098.1522 -1 40555 26440 3 2098.14622 700.3913 Tumor protein D52 OS=Homo sapiens OX=9606 GN=TPD52 PE=1 SV=2 4.49 4006.6 - 1.01E+06 - - - -2.8268 - 2.991 0.44 - 265.4 1 2 1 -0.0059 19 0 0 0 0.00E+00 0.00E+00 - - - 6.1356 1 221125_WJC_METTL3_EV_vs_WT_F03.26443.26443.4 2.93E-12 34/138 K.VIHDNFGIVEGLMTTVHAITATQK[136.11].T "sp|P04406|G3P_HUMAN,tr|E7EUT5|E7EUT5_HUMAN" 2 2602.3669 -1 40556 26443 4 2602.361748 651.599 Glyceraldehyde-3-phosphate dehydrogenase OS=Homo sapiens OX=9606 GN=GAPDH PE=1 SV=3 5.99 4007 - 2.12E+08 - - - -1.9636 - 5.321 0.577 - 821.1 1 2 0 -0.0051 24 0 0 0 0.00E+00 0.00E+00 - - - 4.7833 1 221125_WJC_METTL3_EV_vs_WT_F03.26445.26445.3 1.23E-08 30/92 K.VIHDNFGIVEGLMTTVHAITATQK[136.11].T "sp|P04406|G3P_HUMAN,tr|E7EUT5|E7EUT5_HUMAN" 2 2602.3669 0.86 40558 26445 3 2602.360754 868.4629 Glyceraldehyde-3-phosphate dehydrogenase OS=Homo sapiens OX=9606 GN=GAPDH PE=1 SV=3 5.99 4007.1 - 9.00E+07 - - - -2.3456 - 3.534 0.513 - 754.4 1 2 0 -0.0061 24 0 0 0 1.25E+08 1.46E+08 - - - 7.1899 1 221125_WJC_METTL3_EV_vs_WT_F03.26446.26446.3 7.38E-13 36/92 K.VIHDNFGIVEGLMTTVHAITATQK.T "sp|P04406|G3P_HUMAN,tr|E7EUT5|E7EUT5_HUMAN" 2 2594.3527 -1 40559 26446 3 2594.34878 865.7915 Glyceraldehyde-3-phosphate dehydrogenase OS=Homo sapiens OX=9606 GN=GAPDH PE=1 SV=3 5.99 4007.1 - 8.58E+07 - - - -1.4948 - 6.342 0.729 - 2019.5 1 2 0 -0.0039 24 0 0 0 0.00E+00 0.00E+00 - - - 10.9568 0.9997 221125_WJC_METTL3_EV_vs_WT_F03.26471.26471.3 0.000634 20/44 K.LALDVEIATYRK.L "sp|P48668|K2C6C_HUMAN,sp|Q01546|K22O_HUMAN,sp|P12035|K2C3_HUMAN,sp|P04259|K2C6B_HUMAN,sp|P13647|K2C5_HUMAN,sp|P35908|K22E_HUMAN,sp|O95678|K2C75_HUMAN,sp|Q5XKE5|K2C79_HUMAN,sp|P02538|K2C6A_HUMAN,tr|H0YI76|H0YI76_HUMAN,tr|H0YID6|H0YID6_HUMAN" 11 1390.782 -1 40580 26471 3 1390.785672 464.6013 "Keratin, type II cytoskeletal 6C OS=Homo sapiens OX=9606 GN=KRT6C PE=1 SV=3" 6.07 4009.8 - 2.92E+06 - - - 2.6287 - 2.578 0.347 - 619.7 1 2 0 0.0037 12 0 0 0 0.00E+00 0.00E+00 - - - 5.0327 0.9971 221125_WJC_METTL3_EV_vs_WT_F03.26478.26478.2 0.0528 22-Oct K.LALDVEIATYRK.L "sp|P48668|K2C6C_HUMAN,sp|Q01546|K22O_HUMAN,sp|P12035|K2C3_HUMAN,sp|P04259|K2C6B_HUMAN,sp|P13647|K2C5_HUMAN,sp|P35908|K22E_HUMAN,sp|O95678|K2C75_HUMAN,sp|Q5XKE5|K2C79_HUMAN,sp|P02538|K2C6A_HUMAN,tr|H0YI76|H0YI76_HUMAN,tr|H0YID6|H0YID6_HUMAN" 11 1390.782 -1 40587 26478 2 1390.786673 696.3983 "Keratin, type II cytoskeletal 6C OS=Homo sapiens OX=9606 GN=KRT6C PE=1 SV=3" 6.07 4010.5 - 952088 - - - 3.3485 - 2.15 0.271 - 346.5 1 2 0 0.0047 12 0 0 0 0.00E+00 0.00E+00 - - - 3.0552 1 221125_WJC_METTL3_EV_vs_WT_F03.26479.26479.2 4.28E-07 15/24 K.VNDTIQIDLETGK[136.11].L sp|P62701|RS4X_HUMAN 1 1452.7551 0.02 40588 26479 2 1452.7586 727.3848 "40S ribosomal protein S4, X isoform OS=Homo sapiens OX=9606 GN=RPS4X PE=1 SV=2" 4.03 4010.6 - 911084 - - - 2.3824 - 3.326 0.625 - 683.8 1 2 0 0.0035 13 0 0 0 1.02E+07 4.44E+08 - - - 6.7405 0.9999 221125_WJC_METTL3_EV_vs_WT_F03.27151.27151.3 3.18E-09 13/84 R.KPLVIIAEDVDGEALSTLVLNR.L "sp|P10809|CH60_HUMAN,tr|A0A7I2V2X6|A0A7I2V2X6_HUMAN,tr|A0A7I2YQK6|A0A7I2YQK6_HUMAN,tr|A0A7I2V599|A0A7I2V599_HUMAN,tr|A0A7I2YQ71|A0A7I2YQ71_HUMAN,tr|A0A7I2V5M1|A0A7I2V5M1_HUMAN,tr|A0A7I2V5K3|A0A7I2V5K3_HUMAN" 7 2364.3264 -1 40650 27151 3 2364.337329 789.1161 "60 kDa heat shock protein, mitochondrial OS=Homo sapiens OX=9606 GN=HSPD1 PE=1 SV=2" 4.32 4137 - 1.52E+06 - - - 4.611 - 3.016 0.63 - 171.5 1 2 0 0.0109 22 0 0 0 0.00E+00 0.00E+00 - - - 8.1781 1 221125_WJC_METTL3_EV_vs_WT_F03.27152.27152.3 2.27E-08 14/116 K.DMAIATGGAVFGEEGLTLNLEDVQPHDLGK.V "sp|P10809|CH60_HUMAN,tr|A0A7I2V2X6|A0A7I2V2X6_HUMAN,tr|A0A7I2YQK6|A0A7I2YQK6_HUMAN,tr|A0A7I2V599|A0A7I2V599_HUMAN" 4 3096.5074 -1 40651 27152 3 3096.518192 1033.1764 "60 kDa heat shock protein, mitochondrial OS=Homo sapiens OX=9606 GN=HSPD1 PE=1 SV=2" 4.01 4137 - 1.64E+06 - - - 3.4914 - 3.239 0.654 - 107 1 2 0 0.0108 30 0 0 0 0.00E+00 0.00E+00 - - - 8.5323 1 221125_WJC_METTL3_EV_vs_WT_F03.27153.27153.3 1.95E-10 27/84 R.K[136.11]PLVIIAEDVDGEALSTLVLNR[166.11].L "sp|P10809|CH60_HUMAN,tr|A0A7I2V2X6|A0A7I2V2X6_HUMAN,tr|A0A7I2YQK6|A0A7I2YQK6_HUMAN,tr|A0A7I2V599|A0A7I2V599_HUMAN,tr|A0A7I2YQ71|A0A7I2YQ71_HUMAN,tr|A0A7I2V5M1|A0A7I2V5M1_HUMAN,tr|A0A7I2V5K3|A0A7I2V5K3_HUMAN" 7 2382.3489 -1 40652 27153 3 2382.347134 795.1236 "60 kDa heat shock protein, mitochondrial OS=Homo sapiens OX=9606 GN=HSPD1 PE=1 SV=2" 4.32 4137.1 - 1.05E+06 - - - -0.74 - 4.799 0.62 - 954.7 1 2 0 -0.0018 22 0 0 0 0.00E+00 0.00E+00 - - - 9.1703 0.9475 221125_WJC_METTL3_EV_vs_WT_F04.02505.02505.2 0.834 12-Jul K.LVNNGEK.L sp|Q15393|SF3B3_HUMAN 1 772.4079 1.34 40708 2505 2 772.404943 387.2112 Splicing factor 3B subunit 3 OS=Homo sapiens OX=9606 GN=SF3B3 PE=1 SV=4 6 1213.2 - 379344 - - - -3.8516 - 1.334 0.129 - 151.3 1 2 0 -0.003 7 0 0 0 7.97E+07 5.92E+07 - - - 0.906 0.9898 221125_WJC_METTL3_EV_vs_WT_F04.02581.02581.2 0.0381 14-Aug R.VAAAETAK.H "sp|P46939|UTRN_HUMAN,sp|P11532|DMD_HUMAN,tr|A0A804HJY0|A0A804HJY0_HUMAN,tr|A0A075B6G3|A0A075B6G3_HUMAN,tr|H0Y3E8|H0Y3E8_HUMAN,tr|H0Y304|H0Y304_HUMAN,tr|A0A087WTU7|A0A087WTU7_HUMAN,tr|Q5JT45|Q5JT45_HUMAN,tr|A0A5H1ZRR9|A0A5H1ZRR9_HUMAN,tr|A0A804HKR4|A0A804HKR4_HUMAN,tr|A0A7P0T8I2|A0A7P0T8I2_HUMAN,tr|Q5JT44|Q5JT44_HUMAN,tr|A0A5H1ZRP9|A0A5H1ZRP9_HUMAN,tr|A0A5H1ZRP7|A0A5H1ZRP7_HUMAN,tr|A0A5H1ZRQ8|A0A5H1ZRQ8_HUMAN,tr|A0A5H1ZRQ1|A0A5H1ZRQ1_HUMAN,tr|Q5T097|Q5T097_HUMAN,tr|A0A7P0TAM6|A0A7P0TAM6_HUMAN,tr|A0A087WV90|A0A087WV90_HUMAN,tr|A0A804HKY9|A0A804HKY9_HUMAN,tr|H0Y337|H0Y337_HUMAN,tr|A0A7P0Z4P7|A0A7P0Z4P7_HUMAN,tr|A0A5H1ZRP8|A0A5H1ZRP8_HUMAN,tr|A0A7P0TAW7|A0A7P0TAW7_HUMAN" 24 759.4127 0.96 40717 2581 2 759.409494 380.7136 Utrophin OS=Homo sapiens OX=9606 GN=UTRN PE=1 SV=2 5.97 1226 - 264889 - - - -4.1809 - 1.622 0.257 - 173.7 1 2 0 -0.0032 8 0 0 0 8.09E+06 8.42E+06 - - - 2.3969 0.9852 221125_WJC_METTL3_EV_vs_WT_F04.02668.02668.2 0.087 14-Jul K.TVDGPSGK.L "sp|P04406|G3P_HUMAN,tr|E7EUT5|E7EUT5_HUMAN" 2 759.3763 0.95 40729 2668 2 759.374293 380.6954 Glyceraldehyde-3-phosphate dehydrogenase OS=Homo sapiens OX=9606 GN=GAPDH PE=1 SV=3 5.5 1240.3 - 191584 - - - -2.6206 - 1.226 0.208 - 147.6 1 2 0 -0.002 8 0 0 0 9.22E+06 9.72E+06 - - - 1.1912 0.9916 221125_WJC_METTL3_EV_vs_WT_F04.02681.02681.2 0.118 14-May R.DQINSDHR.T sp|Q12874|SF3A3_HUMAN 1 983.4421 999 40730 2681 2 983.438873 492.7283 Splicing factor 3A subunit 3 OS=Homo sapiens OX=9606 GN=SF3A3 PE=1 SV=1 5.21 1242.5 - 65313.5 - - - -3.2518 - 1.188 0.329 - 90.6 1 2 0 -0.0032 8 0 0 0 2.26E+06 0.00E+00 - - - 1.9896 0.8917 221125_WJC_METTL3_EV_vs_WT_F04.02685.02685.2 0.609 14-May K.MANEAAAK[136.11].N sp|Q96DF8|ESS2_HUMAN 1 812.3942 1.42 40731 2685 2 812.390752 407.2044 Splicing factor ESS-2 homolog OS=Homo sapiens OX=9606 GN=ESS2 PE=1 SV=1 5.75 1243 - 276400 - - - -4.2295 - 1.242 0.154 - 37.1 4 2 0 -0.0034 8 0 0 0 1.34E+07 9.49E+06 - - - 0.5621 0.9965 221125_WJC_METTL3_EV_vs_WT_F04.02887.02887.2 0.0784 12-Jul R.LETAESK[136.11].E sp|Q9UQ35|SRRM2_HUMAN 1 784.4058 0.69 40746 2887 2 784.403838 393.2102 Serine\arginine repetitive matrix protein 2 OS=Homo sapiens OX=9606 GN=SRRM2 PE=1 SV=2 4.53 1276.8 - 762636 - - - -2.5 - 1.571 0.242 - 163.6 1 2 0 -0.002 7 0 0 0 2.71E+07 3.93E+07 - - - 2.2591 0.9782 221125_WJC_METTL3_EV_vs_WT_F04.02930.02930.2 0.0578 12-Aug R.EASNSER[166.11].T tr|A0A7I2YQM0|A0A7I2YQM0_HUMAN 1 801.3492 1.17 40753 2930 2 801.347113 401.6819 Golgi-specific brefeldin A-resistance guanine nucleotide exchange factor 1 (Fragment) OS=Homo sapiens OX=9606 GN=GBF1 PE=1 SV=1 4.53 1283.5 - 531588 - - - -2.6418 - 1.448 0.096 - 277.3 1 2 0 -0.0021 7 0 0 0 3.19E+07 2.71E+07 - - - 0.9223 0.9577 221125_WJC_METTL3_EV_vs_WT_F04.02985.02985.2 2.69 12-Jul R.LAESQAR.L sp|Q6QNY0|BL1S3_HUMAN 1 773.4032 1.43 40761 2985 2 773.401659 387.7089 Biogenesis of lysosome-related organelles complex 1 subunit 3 OS=Homo sapiens OX=9606 GN=BLOC1S3 PE=1 SV=1 6 1292.3 - 2.41E+06 - - - -1.9485 - 1.32 0.029 - 207.2 1 2 0 -0.0015 7 0 0 0 1.02E+08 7.14E+07 - - - 0.1344 0.9119 221125_WJC_METTL3_EV_vs_WT_F04.02990.02990.2 1.79E-06 18-Nov S.AAAAAAAAGR[166.11].L "sp|P26599|PTBP1_HUMAN,sp|Q9UKA9|PTBP2_HUMAN,tr|B4DI28|B4DI28_HUMAN,tr|A0A0U1RRM4|A0A0U1RRM4_HUMAN,tr|A0A6Q8PEZ3|A0A6Q8PEZ3_HUMAN,tr|A6NLN1|A6NLN1_HUMAN,tr|A0A087WU68|A0A087WU68_HUMAN,tr|A0A6Q8PH43|A0A6Q8PH43_HUMAN,tr|A0A7I2RVZ4|A0A7I2RVZ4_HUMAN,tr|A0A6Q8PFE6|A0A6Q8PFE6_HUMAN,tr|A0A6Q8PFC0|A0A6Q8PFC0_HUMAN,tr|A0A7I2V621|A0A7I2V621_HUMAN,tr|A0A087WTS6|A0A087WTS6_HUMAN,tr|K7EK45|K7EK45_HUMAN,tr|A0A6Q8PH82|A0A6Q8PH82_HUMAN" 15 809.4383 1.29 40762 2990 2 809.436868 405.7264 Polypyrimidine tract-binding protein 1 OS=Homo sapiens OX=9606 GN=PTBP1 PE=1 SV=1 9.79 1293 - 587904 - - - -1.7938 - 2.273 0.159 - 541.7 1 1 0 -0.0015 10 0 0 0 4.70E+07 3.64E+07 - - - 2.5069 0.8404 221125_WJC_METTL3_EV_vs_WT_F04.03033.03033.2 0.0141 12-Jul R.MVNDAEK[136.11].F "sp|P11021|BIP_HUMAN,tr|A0A7P0TB36|A0A7P0TB36_HUMAN,tr|A0A7P0TAI0|A0A7P0TAI0_HUMAN" 3 813.3782 0.56 40768 3033 2 813.371178 407.6964 Endoplasmic reticulum chaperone BiP OS=Homo sapiens OX=9606 GN=HSPA5 PE=1 SV=2 4.37 1299.8 - 2.29E+06 - - - -8.638 - 1.247 0.334 - 120.7 1 2 0 -0.007 7 0 0 0 1.24E+08 2.20E+08 - - - 2.2051 0.7959 221125_WJC_METTL3_EV_vs_WT_F04.03036.03036.2 1.17 12-Jul R.LGASQER.H "sp|Q14241|ELOA1_HUMAN,tr|A0A024RAC6|A0A024RAC6_HUMAN" 2 759.3875 1.06 40769 3036 2 759.384083 380.701 Elongin-A OS=Homo sapiens OX=9606 GN=ELOA PE=1 SV=2 6 1300.1 - 3.43E+06 - - - -4.5207 - 1.303 0.045 - 138.3 1 2 0 -0.0034 7 0 0 0 7.20E+07 6.82E+07 - - - 0.2109 0.9903 221125_WJC_METTL3_EV_vs_WT_F04.03047.03047.2 0.0097 12-Jun R.MVNDAEK.F "sp|P11021|BIP_HUMAN,tr|A0A7P0TB36|A0A7P0TB36_HUMAN,tr|A0A7P0TAI0|A0A7P0TAI0_HUMAN" 3 805.364 0.56 40772 3047 2 805.360172 403.6893 Endoplasmic reticulum chaperone BiP OS=Homo sapiens OX=9606 GN=HSPA5 PE=1 SV=2 4.37 1301.7 - 3.02E+06 - - - -4.7581 - 1.381 0.375 - 126 1 2 0 -0.0038 7 0 0 0 1.24E+08 2.20E+08 - - - 2.8324 0.9794 221125_WJC_METTL3_EV_vs_WT_F04.03141.03141.2 2.25 12-Aug K.SAVEAER[166.11].L "sp|P04843|RPN1_HUMAN,tr|B7Z4L4|B7Z4L4_HUMAN" 2 770.3798 1.01 40785 3141 2 770.377103 386.1972 Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit 1 OS=Homo sapiens OX=9606 GN=RPN1 PE=1 SV=1 4.53 1317.1 - 1.57E+06 - - - -3.5035 - 1.533 0.139 - 387.4 1 2 0 -0.0027 7 0 0 0 1.06E+08 1.05E+08 - - - 1.4205 0.9873 221125_WJC_METTL3_EV_vs_WT_F04.03183.03183.2 0.766 12-Jul K.IAEEEAK.A "sp|Q9Y3A4|RRP7A_HUMAN,sp|Q9NSQ0|RRP7B_HUMAN" 2 788.3916 0.68 40791 3183 2 788.389366 395.2031 Ribosomal RNA-processing protein 7 homolog A OS=Homo sapiens OX=9606 GN=RRP7A PE=1 SV=2 4.25 1323.9 - 5.85E+06 - - - -2.8323 - 1.408 0.175 - 152.1 1 2 0 -0.0022 7 0 0 0 3.04E+08 4.46E+08 - - - 1.417 0.959 221125_WJC_METTL3_EV_vs_WT_F04.03194.03194.2 0.409 12-Jul K.SPVEEAK[136.11].S "sp|P07197|NFM_HUMAN,tr|E7ESP9|E7ESP9_HUMAN" 2 766.3952 1.12 40795 3194 2 766.392371 384.2049 Neurofilament medium polypeptide OS=Homo sapiens OX=9606 GN=NEFM PE=1 SV=3 4.53 1325.3 - 1.52E+06 - - - -3.7357 - 1.381 0.131 - 260.5 1 2 0 -0.0029 7 0 0 0 4.17E+07 3.71E+07 - - - 1.0305 0.9794 221125_WJC_METTL3_EV_vs_WT_F04.03230.03230.2 0.0261 12-Aug R.MVQEAEK.Y "sp|P0DMV8|HS71A_HUMAN,sp|P11142|HSP7C_HUMAN,sp|P0DMV9|HS71B_HUMAN,tr|E9PNE6|E9PNE6_HUMAN,tr|A8K7Q2|A8K7Q2_HUMAN,tr|E9PKE3|E9PKE3_HUMAN,tr|E9PM13|E9PM13_HUMAN,tr|E9PS65|E9PS65_HUMAN,tr|V9GZ37|V9GZ37_HUMAN,tr|A0A0G2JIW1|A0A0G2JIW1_HUMAN" 10 833.3953 0.16 40803 3230 2 833.391475 417.7049 Heat shock 70 kDa protein 1A OS=Homo sapiens OX=9606 GN=HSPA1A PE=1 SV=1 4.53 1330.5 - 3.41E+06 - - - -4.5945 - 1.339 0.282 - 241.1 1 2 0 -0.0038 7 0 0 0 3.20E+09 1.97E+10 - - - 2.0476 0.9996 221125_WJC_METTL3_EV_vs_WT_F04.03234.03234.2 4.41E-06 26-Dec R.GSGGGSSGGSIGGR.G sp|P04264|K2C1_HUMAN 1 1091.4956 999 40805 3234 2 1091.492237 546.7551 "Keratin, type II cytoskeletal 1 OS=Homo sapiens OX=9606 GN=KRT1 PE=1 SV=6" 9.75 1331 - 547461 - - - -3.0472 - 2.398 0.567 - 202.2 1 2 0 -0.0033 14 0 0 0 1.01E+07 0.00E+00 - - - 5.4227 0.98 221125_WJC_METTL3_EV_vs_WT_F04.03247.03247.2 0.104 14-Aug K.LENSAAPK.K "sp|Q13435|SF3B2_HUMAN,tr|E9PPJ0|E9PPJ0_HUMAN" 2 828.4341 2.81 40807 3247 2 828.430863 415.2243 Splicing factor 3B subunit 2 OS=Homo sapiens OX=9606 GN=SF3B2 PE=1 SV=2 6 1333 - 1.62E+06 - - - -3.946 - 1.379 0.228 - 190 1 2 0 -0.0033 8 0 0 0 2.92E+08 1.04E+08 - - - 1.6932 0.9504 221125_WJC_METTL3_EV_vs_WT_F04.03248.03248.2 0.0099 14-May K.VMTDESGK[136.11].S "sp|Q9H361|PABP3_HUMAN,sp|P11940|PABP1_HUMAN,tr|A0A7I2YQE4|A0A7I2YQE4_HUMAN,tr|A0A7I2V649|A0A7I2V649_HUMAN,tr|H0YAR2|H0YAR2_HUMAN,tr|E7ERJ7|E7ERJ7_HUMAN,tr|A0A7I2YQ88|A0A7I2YQ88_HUMAN,tr|A0A087WTT1|A0A087WTT1_HUMAN,tr|H0YAP2|H0YAP2_HUMAN,tr|A0A7I2YQ90|A0A7I2YQ90_HUMAN,tr|A0A7I2V4N4|A0A7I2V4N4_HUMAN,tr|E7EQV3|E7EQV3_HUMAN" 12 873.3993 1.36 40808 3248 2 873.394102 437.7069 Polyadenylate-binding protein 3 OS=Homo sapiens OX=9606 GN=PABPC3 PE=1 SV=2 4.37 1333.1 - 1.06E+06 - - - -5.9892 - 1.179 0.367 - 73.2 2 2 0 -0.0052 8 0 0 0 5.25E+07 3.87E+07 - - - 2.1122 0.9759 221125_WJC_METTL3_EV_vs_WT_F04.03256.03256.2 0.47 12-Jun R.IVEEANK[136.11].A "sp|P30519|HMOX2_HUMAN,tr|I3L159|I3L159_HUMAN,tr|A0A087WT44|A0A087WT44_HUMAN,tr|I3L1Y2|I3L1Y2_HUMAN,tr|I3L1F5|I3L1F5_HUMAN" 5 809.4374 1.14 40811 3256 2 809.434381 405.726 Heme oxygenase 2 OS=Homo sapiens OX=9606 GN=HMOX2 PE=1 SV=2 4.53 1334.1 - 3.64E+06 - - - -3.7705 - 1.435 0.171 - 98.7 1 2 0 -0.0031 7 0 0 0 1.44E+08 1.26E+08 - - - 1.4474 0.9829 221125_WJC_METTL3_EV_vs_WT_F04.03261.03261.2 0.0236 14-Jul K.VMTDESGK.S "sp|Q9H361|PABP3_HUMAN,sp|P11940|PABP1_HUMAN,tr|A0A7I2YQE4|A0A7I2YQE4_HUMAN,tr|A0A7I2V649|A0A7I2V649_HUMAN,tr|H0YAR2|H0YAR2_HUMAN,tr|E7ERJ7|E7ERJ7_HUMAN,tr|A0A7I2YQ88|A0A7I2YQ88_HUMAN,tr|A0A087WTT1|A0A087WTT1_HUMAN,tr|H0YAP2|H0YAP2_HUMAN,tr|A0A7I2YQ90|A0A7I2YQ90_HUMAN,tr|A0A7I2V4N4|A0A7I2V4N4_HUMAN,tr|E7EQV3|E7EQV3_HUMAN" 12 865.3851 1.36 40814 3261 2 865.381498 433.6998 Polyadenylate-binding protein 3 OS=Homo sapiens OX=9606 GN=PABPC3 PE=1 SV=2 4.37 1334.6 - 2.23E+06 - - - -4.2004 - 1.202 0.321 - 193.6 1 2 0 -0.0036 8 0 0 0 5.25E+07 3.86E+07 - - - 1.9657 0.9896 221125_WJC_METTL3_EV_vs_WT_F04.03300.03300.2 0.0105 12-Jul R.MVQEAEK[136.11].Y "sp|P0DMV8|HS71A_HUMAN,sp|P11142|HSP7C_HUMAN,sp|P0DMV9|HS71B_HUMAN,tr|E9PNE6|E9PNE6_HUMAN,tr|A8K7Q2|A8K7Q2_HUMAN,tr|E9PKE3|E9PKE3_HUMAN,tr|E9PM13|E9PM13_HUMAN,tr|E9PS65|E9PS65_HUMAN,tr|V9GZ37|V9GZ37_HUMAN,tr|A0A0G2JIW1|A0A0G2JIW1_HUMAN" 10 841.4095 0.16 40815 3300 2 841.405914 421.712 Heat shock 70 kDa protein 1A OS=Homo sapiens OX=9606 GN=HSPA1A PE=1 SV=1 4.53 1341.3 - 2.86E+06 - - - -4.2667 - 1.436 0.305 - 173.1 1 2 0 -0.0036 7 0 0 0 3.20E+09 1.97E+10 - - - 2.4392 0.9786 221125_WJC_METTL3_EV_vs_WT_F04.03304.03304.2 3.67 12-Jul R.YVETQAK.E "sp|Q9UBQ5|EIF3K_HUMAN,tr|K7ERF1|K7ERF1_HUMAN,tr|K7ES31|K7ES31_HUMAN" 3 837.4232 1.04 40817 3304 2 837.419808 419.7189 Eukaryotic translation initiation factor 3 subunit K OS=Homo sapiens OX=9606 GN=EIF3K PE=1 SV=1 6 1341.8 - 2.96E+06 - - - -4.0899 - 1.326 0.242 - 137.1 1 2 0 -0.0034 7 0 0 0 7.96E+07 7.68E+07 - - - 1.7214 0.998 221125_WJC_METTL3_EV_vs_WT_F04.03319.03319.2 0.0879 12-Jul R.MVGC[160.03]TGK[136.11].V "sp|P22061|PIMT_HUMAN,tr|F6S8N6|F6S8N6_HUMAN,tr|A0A3F2YNX8|A0A3F2YNX8_HUMAN,tr|C9J0F2|C9J0F2_HUMAN,tr|A0A0A0MRJ6|A0A0A0MRJ6_HUMAN" 5 759.3499 0.001 40822 3319 2 759.347499 380.6822 Protein-L-isoaspartate(D-aspartate) O-methyltransferase OS=Homo sapiens OX=9606 GN=PCMT1 PE=1 SV=4 7.98 1343.8 - 508198 - - - -3.1369 - 1.437 0.411 - 178.3 1 2 0 -0.0024 7 0 0 0 0.00E+00 3.22E+07 - - - 3.2247 0.9911 221125_WJC_METTL3_EV_vs_WT_F04.03325.03325.2 0.461 12-Jul R.MEEEAAR.L "sp|Q6Y7W6|GGYF2_HUMAN,tr|A0A7I2V3H7|A0A7I2V3H7_HUMAN,tr|I1E4Y6|I1E4Y6_HUMAN,tr|A0A7I2V516|A0A7I2V516_HUMAN,tr|A0A7I2V3H0|A0A7I2V3H0_HUMAN,tr|A0A7I2V361|A0A7I2V361_HUMAN" 6 834.3542 0.7 40824 3325 2 834.351349 418.1844 GRB10-interacting GYF protein 2 OS=Homo sapiens OX=9606 GN=GIGYF2 PE=1 SV=1 4.25 1344.6 - 5.59E+06 - - - -3.3775 - 1.484 0.234 - 253.3 1 2 0 -0.0028 7 0 0 0 1.30E+08 1.87E+08 - - - 2.0192 0.9753 221125_WJC_METTL3_EV_vs_WT_F04.03366.03366.2 0.226 12-Jun R.ETAQALK[136.11].T "sp|Q9Y4G6|TLN2_HUMAN,sp|P18621|RL17_HUMAN,tr|A0A087WWH0|A0A087WWH0_HUMAN,tr|A0A1B0GVU7|A0A1B0GVU7_HUMAN,tr|J3QS96|J3QS96_HUMAN,tr|J3QLC8|J3QLC8_HUMAN,tr|J3QQT2|J3QQT2_HUMAN,tr|J3KSJ0|J3KSJ0_HUMAN,tr|A0A087WY81|A0A087WY81_HUMAN,tr|J3KRB3|J3KRB3_HUMAN,tr|J3KRX5|J3KRX5_HUMAN,tr|A0A087WXM6|A0A087WXM6_HUMAN,tr|H0YMT1|H0YMT1_HUMAN,tr|A0A0A6YYL6|A0A0A6YYL6_HUMAN" 14 767.4269 0.9 40831 3366 2 767.424088 384.7207 Talin-2 OS=Homo sapiens OX=9606 GN=TLN2 PE=1 SV=4 6.1 1350.8 - 1.08E+07 - - - -3.6238 - 1.349 0.184 - 198.9 1 2 0 -0.0028 7 0 0 0 5.73E+08 6.36E+08 - - - 1.3477 0.8953 221125_WJC_METTL3_EV_vs_WT_F04.03378.03378.2 7.27 12-May R.ETAQALK.T "sp|Q9Y4G6|TLN2_HUMAN,sp|P18621|RL17_HUMAN,tr|A0A087WWH0|A0A087WWH0_HUMAN,tr|A0A1B0GVU7|A0A1B0GVU7_HUMAN,tr|J3QS96|J3QS96_HUMAN,tr|J3QLC8|J3QLC8_HUMAN,tr|J3QQT2|J3QQT2_HUMAN,tr|J3KSJ0|J3KSJ0_HUMAN,tr|A0A087WY81|A0A087WY81_HUMAN,tr|J3KRB3|J3KRB3_HUMAN,tr|J3KRX5|J3KRX5_HUMAN,tr|A0A087WXM6|A0A087WXM6_HUMAN,tr|H0YMT1|H0YMT1_HUMAN,tr|A0A0A6YYL6|A0A0A6YYL6_HUMAN" 14 759.4127 0.9 40833 3378 2 759.410123 380.7136 Talin-2 OS=Homo sapiens OX=9606 GN=TLN2 PE=1 SV=4 6.1 1352.6 - 1.66E+07 - - - -3.3526 - 1.149 0.093 - 165.1 1 2 0 -0.0025 7 0 0 0 5.72E+08 6.36E+08 - - - 0.1672 0.9616 221125_WJC_METTL3_EV_vs_WT_F04.03392.03392.2 0.0674 12-Jul K.YVDEASK.K "sp|P62249|RS16_HUMAN,tr|M0R210|M0R210_HUMAN" 2 810.3759 0.92 40835 3392 2 810.371288 406.1953 40S ribosomal protein S16 OS=Homo sapiens OX=9606 GN=RPS16 PE=1 SV=2 4.37 1354.8 - 3.86E+06 - - - -5.7517 - 1.28 0.322 - 165 1 2 0 -0.0047 7 0 0 0 1.46E+08 1.58E+08 - - - 2.2 0.9896 221125_WJC_METTL3_EV_vs_WT_F04.03413.03413.2 0.0879 12-Jul K.YVDEASK[136.11].K "sp|P62249|RS16_HUMAN,tr|M0R210|M0R210_HUMAN" 2 818.3901 0.94 40840 3413 2 818.387439 410.2024 40S ribosomal protein S16 OS=Homo sapiens OX=9606 GN=RPS16 PE=1 SV=2 4.37 1357.8 - 3.62E+06 - - - -3.3114 - 1.216 0.296 - 155.3 1 2 0 -0.0027 7 0 0 0 1.48E+08 1.58E+08 - - - 1.8461 0.9744 221125_WJC_METTL3_EV_vs_WT_F04.03441.03441.2 1.38 12-Jul K.LAEQAER.Y "sp|P31946|1433B_HUMAN,sp|P62258|1433E_HUMAN,sp|P27348|1433T_HUMAN,sp|P63104|1433Z_HUMAN,sp|Q04917|1433F_HUMAN,sp|P31947|1433S_HUMAN,sp|P61981|1433G_HUMAN,tr|E7EX29|E7EX29_HUMAN,tr|Q4VY19|Q4VY19_HUMAN,tr|B4DJF2|B4DJF2_HUMAN,tr|I3L0W5|I3L0W5_HUMAN,tr|Q4VY20|Q4VY20_HUMAN,tr|A2IDB1|A2IDB1_HUMAN,tr|E5RIR4|E5RIR4_HUMAN,tr|E9PG15|E9PG15_HUMAN,tr|I3L3T1|I3L3T1_HUMAN,tr|E7EVZ2|E7EVZ2_HUMAN,tr|F8WEB6|F8WEB6_HUMAN,tr|E5RGE1|E5RGE1_HUMAN,tr|E9PD24|E9PD24_HUMAN,tr|A0A0J9YWE8|A0A0J9YWE8_HUMAN,tr|E7ESK7|E7ESK7_HUMAN" 22 815.4137 1.23 40845 3441 2 815.411232 408.7141 14-3-3 protein beta\alpha OS=Homo sapiens OX=9606 GN=YWHAB PE=1 SV=3 4.53 1362 - 2.63E+06 - - - -3.0647 - 1.524 0.088 - 184.4 1 2 0 -0.0025 7 0 0 0 2.75E+09 2.23E+09 - - - 1.0252 0.8459 221125_WJC_METTL3_EV_vs_WT_F04.03501.03501.2 5.85 16-May R.TAHMGPGPR[166.11].L tr|J3QLM1|J3QLM1_HUMAN 1 932.4526 0.71 40853 3501 2 932.454884 467.2336 StAR-related lipid transfer protein 3 OS=Homo sapiens OX=9606 GN=STARD3 PE=1 SV=1 9.44 1371.6 - 430560 - - - 2.4602 - 1.202 0.033 - 97 5 2 0 0.0023 9 0 0 0 3.72E+07 5.24E+07 - - - -0.4959 0.9865 221125_WJC_METTL3_EV_vs_WT_F04.03503.03503.2 2.12 12-Jun K.AEGSEIR[166.11].L "sp|P07237|PDIA1_HUMAN,tr|A0A7P0TA97|A0A7P0TA97_HUMAN,tr|A0A7P0T8C0|A0A7P0T8C0_HUMAN,tr|H7BZ94|H7BZ94_HUMAN,tr|A0A7P0TA71|A0A7P0TA71_HUMAN,tr|I3L4M2|I3L4M2_HUMAN,tr|A0A7P0T9D6|A0A7P0T9D6_HUMAN,tr|H0Y3Z3|H0Y3Z3_HUMAN,tr|A0A7P0Z4S2|A0A7P0Z4S2_HUMAN,tr|I3NI03|I3NI03_HUMAN,tr|A0A7P0TA35|A0A7P0TA35_HUMAN,tr|A0A7P0TAX9|A0A7P0TAX9_HUMAN,tr|I3L514|I3L514_HUMAN,tr|A0A7P0Z476|A0A7P0Z476_HUMAN,tr|A0A7P0TBP8|A0A7P0TBP8_HUMAN,tr|A0A7P0TB26|A0A7P0TB26_HUMAN,tr|A0A7P0T9U6|A0A7P0T9U6_HUMAN,tr|I3L0S0|I3L0S0_HUMAN,tr|A0A7P0T8J3|A0A7P0T8J3_HUMAN,tr|A0A7P0Z4J0|A0A7P0Z4J0_HUMAN,tr|A0A7P0T9S9|A0A7P0T9S9_HUMAN,tr|A0A7P0T8X1|A0A7P0T8X1_HUMAN,tr|I3L3U6|I3L3U6_HUMAN" 23 770.3798 1.61 40854 3503 2 770.377688 386.1972 Protein disulfide-isomerase OS=Homo sapiens OX=9606 GN=P4HB PE=1 SV=3 4.53 1371.8 - 4.21E+06 - - - -2.7441 - 1.303 0.196 - 200.4 1 2 0 -0.0021 7 0 0 0 2.53E+08 1.57E+08 - - - 1.3266 0.9601 221125_WJC_METTL3_EV_vs_WT_F04.03504.03504.2 0.94 12-Jun K.QLAAENR[166.11].L sp|P35579|MYH9_HUMAN 1 810.4223 1.32 40855 3504 2 810.420216 406.2184 Myosin-9 OS=Homo sapiens OX=9606 GN=MYH9 PE=1 SV=4 6 1371.8 - 2.47E+06 - - - -2.6159 - 1.136 0.141 - 244.1 1 2 0 -0.0021 7 0 0 0 4.36E+08 3.31E+08 - - - 0.4858 0.9856 221125_WJC_METTL3_EV_vs_WT_F04.03510.03510.2 0.0441 12-Jun R.NDEELNK.L "sp|P16104|H2AX_HUMAN,sp|Q9BTM1|H2AJ_HUMAN,sp|Q93077|H2A1C_HUMAN,sp|Q99878|H2A1J_HUMAN,sp|Q16777|H2A2C_HUMAN,sp|Q8IUE6|H2A2B_HUMAN,sp|Q96QV6|H2A1A_HUMAN,sp|P04908|H2A1B_HUMAN,sp|P20671|H2A1D_HUMAN,sp|P0C0S8|H2A1_HUMAN,sp|Q6FI13|H2A2A_HUMAN,sp|Q96KK5|H2A1H_HUMAN,sp|Q7L7L0|H2A3_HUMAN,tr|A0A0U1RR32|A0A0U1RR32_HUMAN,tr|A0A0U1RRH7|A0A0U1RRH7_HUMAN,tr|A0A3B3IS11|A0A3B3IS11_HUMAN,tr|H0YFX9|H0YFX9_HUMAN" 17 860.3876 1.02 40858 3510 2 860.384516 431.2011 Histone H2AX OS=Homo sapiens OX=9606 GN=H2AX PE=1 SV=2 4.14 1372.6 - 514877 - - - -3.5565 - 1.354 0.234 - 160.3 1 2 0 -0.0031 7 0 0 0 3.47E+07 3.41E+07 - - - 1.7286 0.975 221125_WJC_METTL3_EV_vs_WT_F04.03524.03524.2 0.444 12-Jul K.VTQQGLK[136.11].M "sp|P49327|FAS_HUMAN,tr|A0A0U1RQF0|A0A0U1RQF0_HUMAN" 2 780.4585 0.54 40864 3524 2 780.456211 391.2365 Fatty acid synthase OS=Homo sapiens OX=9606 GN=FASN PE=1 SV=3 8.72 1374.4 - 2.36E+06 - - - -2.9367 - 1.197 0.185 - 129.4 1 2 0 -0.0023 7 0 0 0 8.63E+07 1.60E+08 - - - 0.9765 0.9814 221125_WJC_METTL3_EV_vs_WT_F04.03528.03528.2 0.0552 12-Jun R.LEPSTC[160.03]K[136.11].T "sp|Q9Y4W2|LAS1L_HUMAN,tr|A0A7I2V4E5|A0A7I2V4E5_HUMAN" 2 841.4095 2.29 40865 3528 2 841.406108 421.712 Ribosomal biogenesis protein LAS1L OS=Homo sapiens OX=9606 GN=LAS1L PE=1 SV=2 5.99 1374.9 - 310925 - - - -4.0361 - 1.042 0.356 - 154 1 2 0 -0.0034 7 0 0 0 9.74E+07 4.25E+07 - - - 1.7997 0.9942 221125_WJC_METTL3_EV_vs_WT_F04.03536.03536.2 0.427 14-Jun R.LSPATENK.L "sp|Q8N1F7|NUP93_HUMAN,tr|H3BPA9|H3BPA9_HUMAN,tr|H3BVG0|H3BVG0_HUMAN" 3 858.4447 1.07 40867 3536 2 858.443498 430.2296 Nuclear pore complex protein Nup93 OS=Homo sapiens OX=9606 GN=NUP93 PE=1 SV=2 6 1376.1 - 659713 - - - -1.3967 - 1.404 0.163 - 142.8 1 2 0 -0.0012 8 0 0 0 4.14E+07 3.85E+07 - - - 1.2679 0.9927 221125_WJC_METTL3_EV_vs_WT_F04.03550.03550.2 0.129 12-Jul R.STGETIR.S "sp|P17987|TCPA_HUMAN,tr|F5GZ03|F5GZ03_HUMAN,tr|F5GZI8|F5GZI8_HUMAN,tr|E7ERF2|E7ERF2_HUMAN,tr|F5GYL4|F5GYL4_HUMAN" 5 762.3872 0.42 40871 3550 2 762.387684 382.2009 T-complex protein 1 subunit alpha OS=Homo sapiens OX=9606 GN=TCP1 PE=1 SV=1 5.72 1378.1 - 1.04E+06 - - - 0.6585 - 1.41 0.108 - 264.4 1 2 0 0.0005 7 0 0 0 4.02E+07 9.48E+07 - - - 0.9272 0.9985 221125_WJC_METTL3_EV_vs_WT_F04.03552.03552.2 0.00786 16-Jul K.VVTAAAQAK[136.11].Q "sp|Q13428|TCOF_HUMAN,tr|E7ETY2|E7ETY2_HUMAN,tr|H0Y8Y7|H0Y8Y7_HUMAN,tr|A0A3B3IS06|A0A3B3IS06_HUMAN,tr|A0A6I8PRA0|A0A6I8PRA0_HUMAN" 5 865.5113 0.98 40872 3552 2 865.509796 433.7629 Treacle protein OS=Homo sapiens OX=9606 GN=TCOF1 PE=1 SV=3 8.72 1378.3 - 568440 - - - -1.6996 - 1.271 0.376 - 125.1 1 2 0 -0.0015 9 0 0 0 1.03E+08 1.05E+08 - - - 2.5114 0.9993 221125_WJC_METTL3_EV_vs_WT_F04.03559.03559.2 0.0108 16-Sep K.VVTAAAQAK.Q "sp|Q13428|TCOF_HUMAN,tr|E7ETY2|E7ETY2_HUMAN,tr|H0Y8Y7|H0Y8Y7_HUMAN,tr|A0A3B3IS06|A0A3B3IS06_HUMAN,tr|A0A6I8PRA0|A0A6I8PRA0_HUMAN" 5 857.4971 0.98 40874 3559 2 857.495859 429.7558 Treacle protein OS=Homo sapiens OX=9606 GN=TCOF1 PE=1 SV=3 8.72 1379.3 - 1.18E+06 - - - -1.4088 - 1.488 0.396 - 256.1 1 2 0 -0.0012 9 0 0 0 1.03E+08 1.05E+08 - - - 3.1153 0.9959 221125_WJC_METTL3_EV_vs_WT_F04.03562.03562.2 0.308 14-May R.LTDTEAEK.S sp|Q9BV73|CP250_HUMAN 1 905.4342 0.4 40876 3562 2 905.433844 453.7244 Centrosome-associated protein CEP250 OS=Homo sapiens OX=9606 GN=CEP250 PE=1 SV=2 4.14 1379.7 - 143353 - - - -0.3843 - 1.16 0.258 - 54.3 2 2 0 -0.0003 8 0 0 0 1.56E+07 3.86E+07 - - - 1.2596 0.9984 221125_WJC_METTL3_EV_vs_WT_F04.03577.03577.2 0.0275 14-Jul R.LQPGDTAK.A sp|O94906|PRP6_HUMAN 1 828.4341 1.94 40881 3577 2 828.433922 415.2243 Pre-mRNA-processing factor 6 OS=Homo sapiens OX=9606 GN=PRPF6 PE=1 SV=1 5.84 1381.8 - 2.77E+06 - - - -0.2535 - 1.315 0.285 - 144 1 2 0 -0.0002 8 0 0 0 2.23E+08 1.15E+08 - - - 1.9718 0.9252 221125_WJC_METTL3_EV_vs_WT_F04.03617.03617.2 0.00298 12-Aug R.LLEEHAK[136.11].L "sp|P51572|BAP31_HUMAN,tr|A0A2R8Y5M6|A0A2R8Y5M6_HUMAN" 2 846.4691 1.09 40894 3617 2 846.461518 424.2418 B-cell receptor-associated protein 31 OS=Homo sapiens OX=9606 GN=BCAP31 PE=1 SV=3 5.4 1387 - 3.23E+06 - - - -8.9194 - 1.55 0.352 - 168.4 1 2 0 -0.0076 7 0 0 0 1.28E+08 1.18E+08 - - - 3.0271 0.9975 221125_WJC_METTL3_EV_vs_WT_F04.03634.03634.2 0.0208 14-Sep K.VGAVDADK[136.11].H sp|Q15084|PDIA6_HUMAN 1 781.4061 0.06 40896 3634 2 781.402871 391.7103 Protein disulfide-isomerase A6 OS=Homo sapiens OX=9606 GN=PDIA6 PE=1 SV=1 4.21 1389.7 - 1.78E+06 - - - -4.1745 - 2.134 0.347 - 222 1 2 0 -0.0033 8 0 0 0 1.07E+08 1.67E+09 - - - 3.889 0.964 221125_WJC_METTL3_EV_vs_WT_F04.03650.03650.2 0.347 16-Jul R.SAVPPGADK[136.11].K "sp|P46783|RS10_HUMAN,tr|F6U211|F6U211_HUMAN,tr|A0A1W2PQS6|A0A1W2PQS6_HUMAN,tr|A0A2R8YFH6|A0A2R8YFH6_HUMAN,tr|A0A2R8Y7H1|A0A2R8Y7H1_HUMAN,tr|S4R435|S4R435_HUMAN" 6 848.4483 0.96 40901 3650 2 848.444562 425.2314 40S ribosomal protein S10 OS=Homo sapiens OX=9606 GN=RPS10 PE=1 SV=1 5.55 1391.9 - 1.45E+06 - - - -4.4434 - 1.327 0.223 - 154.7 1 2 0 -0.0038 9 0 0 0 3.11E+08 3.23E+08 - - - 1.5054 0.9934 221125_WJC_METTL3_EV_vs_WT_F04.03652.03652.2 0.764 12-Jun K.ELAQTTR[166.11].T "sp|P50990|TCPQ_HUMAN,tr|H7C4C8|H7C4C8_HUMAN" 2 827.4377 0.34 40902 3652 2 827.436019 414.7261 T-complex protein 1 subunit theta OS=Homo sapiens OX=9606 GN=CCT8 PE=1 SV=4 6.1 1392.2 - 1.72E+07 - - - -1.9724 - 1.422 0.174 - 199.8 1 2 0 -0.0016 7 0 0 0 1.05E+09 3.06E+09 - - - 1.4412 0.9942 221125_WJC_METTL3_EV_vs_WT_F04.03653.03653.2 1.32 12-Jun K.ELAQTTR.T "sp|P50990|TCPQ_HUMAN,tr|H7C4C8|H7C4C8_HUMAN" 2 817.4294 0.34 40903 3653 2 817.428237 409.722 T-complex protein 1 subunit theta OS=Homo sapiens OX=9606 GN=CCT8 PE=1 SV=4 6.1 1392.2 - 3.80E+06 - - - -1.3995 - 1.311 0.185 - 242.3 1 2 0 -0.0011 7 0 0 0 1.05E+09 3.06E+09 - - - 1.2651 0.9933 221125_WJC_METTL3_EV_vs_WT_F04.03664.03664.2 0.0414 14-Jun K.EGVEEAAK[136.11].T "sp|O43615|TIM44_HUMAN,tr|M0QXU7|M0QXU7_HUMAN" 2 839.4116 1.41 40906 3664 2 839.409355 420.7131 Mitochondrial import inner membrane translocase subunit TIM44 OS=Homo sapiens OX=9606 GN=TIMM44 PE=1 SV=2 4.25 1393.7 - 4.07E+06 - - - -2.6888 - 1.328 0.262 - 119.3 1 2 0 -0.0023 8 0 0 0 1.80E+08 1.28E+08 - - - 1.831 0.9987 221125_WJC_METTL3_EV_vs_WT_F04.03665.03665.2 0.0518 12-Sep M.PENVAPR[166.11].S sp|P50991|TCPD_HUMAN 1 791.4165 0.36 40907 3665 2 791.414758 396.7155 T-complex protein 1 subunit delta OS=Homo sapiens OX=9606 GN=CCT4 PE=1 SV=4 6.43 1393.8 - 5.05E+06 - - - -2.2289 - 1.883 0.262 - 270 1 2 0 -0.0018 7 0 0 0 1.66E+09 4.59E+09 - - - 2.9809 0.9778 221125_WJC_METTL3_EV_vs_WT_F04.03680.03680.2 0.697 12-Aug R.QLAQEER[166.11].K "sp|Q6ZQQ6|WDR87_HUMAN,tr|E7ESW6|E7ESW6_HUMAN" 2 882.4435 3.87 40909 3680 2 882.441145 442.229 WD repeat-containing protein 87 OS=Homo sapiens OX=9606 GN=WDR87 PE=1 SV=3 4.53 1396.2 - 1.05E+06 - - - -2.6291 - 1.754 0.058 - 375.1 6 2 0 -0.0023 7 0 0 0 1.28E+08 3.30E+07 - - - 0.9015 0.9381 221125_WJC_METTL3_EV_vs_WT_F04.03717.03717.2 0.264 14-Jun R.VYGTTGTK.V "sp|Q6UN15|FIP1_HUMAN,tr|A0A0B4J203|A0A0B4J203_HUMAN" 2 825.4232 29.74 40917 3717 2 825.419933 413.7189 Pre-mRNA 3'-end-processing factor FIP1 OS=Homo sapiens OX=9606 GN=FIP1L1 PE=1 SV=1 8.56 1401.7 - 2.88E+06 - - - -3.9979 - 1.192 0.193 - 104.3 2 2 0 -0.0033 8 0 0 0 2.78E+09 9.36E+07 - - - 0.8607 0.9456 221125_WJC_METTL3_EV_vs_WT_F04.03731.03731.2 0.223 12-Aug K.LEDAEAR.E sp|L0R8F8|MIDUO_HUMAN 1 802.3821 0.96 40922 3731 2 802.379817 402.1983 MIEF1 upstream open reading frame protein OS=Homo sapiens OX=9606 GN=MIEF1 PE=1 SV=1 4.14 1403.7 - 6.61E+06 - - - -2.8415 - 1.401 0.037 - 274.9 1 2 0 -0.0023 7 0 0 0 1.62E+08 1.69E+08 - - - 0.382 0.9898 221125_WJC_METTL3_EV_vs_WT_F04.03753.03753.2 0.0788 14-Jul K.VAC[160.03]ETVAK[136.11].T sp|P31153|METK2_HUMAN 1 884.4517 1.28 40930 3753 2 884.449084 443.2331 S-adenosylmethionine synthase isoform type-2 OS=Homo sapiens OX=9606 GN=MAT2A PE=1 SV=1 5.97 1406.6 - 602483 - - - -2.9612 - 1.26 0.26 - 147.2 1 2 0 -0.0026 8 0 0 0 1.27E+08 9.97E+07 - - - 1.6576 0.9607 221125_WJC_METTL3_EV_vs_WT_F04.03757.03757.2 0.0919 14-Jul E.ATAEGALK.A "sp|Q9Y618|NCOR2_HUMAN,tr|C9JQE8|C9JQE8_HUMAN,tr|C9J7T7|C9J7T7_HUMAN,tr|C9JE98|C9JE98_HUMAN,tr|C9J0Q5|C9J0Q5_HUMAN,tr|A0A384DVL6|A0A384DVL6_HUMAN" 6 759.4127 1.57 40932 3757 2 759.412279 380.7136 Nuclear receptor corepressor 2 OS=Homo sapiens OX=9606 GN=NCOR2 PE=1 SV=3 6.05 1407.1 - 1.98E+07 - - - -0.5136 - 1.542 0.325 - 203.7 1 1 0 -0.0004 8 0 0 0 1.61E+09 1.02E+09 - - - 2.7475 0.8661 221125_WJC_METTL3_EV_vs_WT_F04.03758.03758.2 0.488 12-Jun L.LEGEEC[160.03]R.M "sp|Q86Y46|K2C73_HUMAN,sp|Q7RTS7|K2C74_HUMAN,sp|P48668|K2C6C_HUMAN,sp|Q01546|K22O_HUMAN,sp|P12036|NFH_HUMAN,sp|Q8N1N4|K2C78_HUMAN,sp|P04259|K2C6B_HUMAN,sp|P13647|K2C5_HUMAN,sp|P35908|K22E_HUMAN,sp|O95678|K2C75_HUMAN,sp|P02538|K2C6A_HUMAN,tr|H0YI76|H0YI76_HUMAN,tr|H0YIC5|H0YIC5_HUMAN,tr|F8W1S1|F8W1S1_HUMAN" 14 891.3756 9.62 40933 3758 2 891.374924 446.6951 "Keratin, type II cytoskeletal 73 OS=Homo sapiens OX=9606 GN=KRT73 PE=1 SV=1" 4.25 1407.2 - 672254 - - - -0.7932 - 1.185 0.284 - 127.9 1 1 0 -0.0007 7 0 0 0 1.89E+07 1.97E+06 - - - 1.6762 0.9776 221125_WJC_METTL3_EV_vs_WT_F04.03767.03767.2 1.2 12-Jul R.IITQGEK.A "sp|P13861|KAP2_HUMAN,tr|H7C4A9|H7C4A9_HUMAN" 2 787.444 1.93 40937 3767 2 787.442575 394.7293 cAMP-dependent protein kinase type II-alpha regulatory subunit OS=Homo sapiens OX=9606 GN=PRKAR2A PE=1 SV=2 6 1408.4 - 769190 - - - -1.7703 - 1.335 0.071 - 116.3 1 2 0 -0.0014 7 0 0 0 4.04E+08 2.10E+08 - - - 0.4805 0.995 221125_WJC_METTL3_EV_vs_WT_F04.03771.03771.2 0.0475 14-Aug R.LVAAEQQK[136.11].A "sp|Q9Y5J9|TIM8B_HUMAN,tr|G3XAN8|G3XAN8_HUMAN,tr|E9PIR3|E9PIR3_HUMAN" 3 893.5062 1.51 40939 3771 2 893.504438 447.7604 Mitochondrial import inner membrane translocase subunit Tim8 B OS=Homo sapiens OX=9606 GN=TIMM8B PE=1 SV=1 6 1408.9 - 738562 - - - -1.9519 - 1.509 0.185 - 173.3 1 2 0 -0.0017 8 0 0 0 1.50E+08 9.98E+07 - - - 1.6478 0.9975 221125_WJC_METTL3_EV_vs_WT_F04.03772.03772.2 0.00928 14-Aug K.LGETDEEK[136.11].L "sp|Q9Y3D9|RT23_HUMAN,tr|J3QLR8|J3QLR8_HUMAN" 2 927.4277 1.34 40940 3772 2 927.424912 464.7211 "28S ribosomal protein S23, mitochondrial OS=Homo sapiens OX=9606 GN=MRPS23 PE=1 SV=2" 4 1409 - 489696 - - - -2.9587 - 1.447 0.371 - 163.5 1 2 0 -0.0027 8 0 0 0 1.14E+08 8.53E+07 - - - 2.8947 0.9966 221125_WJC_METTL3_EV_vs_WT_F04.03773.03773.2 0.181 14-Aug K.LGETDEEK.L "sp|Q9Y3D9|RT23_HUMAN,tr|J3QLR8|J3QLR8_HUMAN" 2 919.4135 1.34 40941 3773 2 919.411295 460.714 "28S ribosomal protein S23, mitochondrial OS=Homo sapiens OX=9606 GN=MRPS23 PE=1 SV=2" 4 1409.2 - 685154 - - - -2.3504 - 1.395 0.29 - 125.3 1 2 0 -0.0022 8 0 0 0 1.14E+08 8.53E+07 - - - 2.1863 0.9662 221125_WJC_METTL3_EV_vs_WT_F04.03785.03785.2 0.227 14-Jun R.LVAAEQQK.A "sp|Q9Y5J9|TIM8B_HUMAN,tr|G3XAN8|G3XAN8_HUMAN,tr|E9PIR3|E9PIR3_HUMAN" 3 885.492 1.51 40944 3785 2 885.489258 443.7533 Mitochondrial import inner membrane translocase subunit Tim8 B OS=Homo sapiens OX=9606 GN=TIMM8B PE=1 SV=1 6 1411 - 4.47E+06 - - - -3.0763 - 1.154 0.184 - 96.6 1 2 0 -0.0027 8 0 0 0 1.50E+08 9.98E+07 - - - 0.8312 0.9986 221125_WJC_METTL3_EV_vs_WT_F04.03792.03792.2 0.0553 14-Aug K.VAC[160.03]ETVAK.T sp|P31153|METK2_HUMAN 1 876.4375 1.15 40946 3792 2 876.436625 439.226 S-adenosylmethionine synthase isoform type-2 OS=Homo sapiens OX=9606 GN=MAT2A PE=1 SV=1 5.97 1411.9 - 5.32E+06 - - - -1.0018 - 1.491 0.268 - 188.4 1 2 0 -0.0009 8 0 0 0 1.28E+08 1.11E+08 - - - 2.2249 0.994 221125_WJC_METTL3_EV_vs_WT_F04.03802.03802.2 0.0102 14-Jul K.LVSATTGK.V "sp|Q13685|AAMP_HUMAN,tr|H7C0R2|H7C0R2_HUMAN,tr|C9JG97|C9JG97_HUMAN,tr|C9JEH3|C9JEH3_HUMAN" 4 775.444 0.87 40948 3802 2 775.441672 388.7293 Angio-associated migratory cell protein OS=Homo sapiens OX=9606 GN=AAMP PE=1 SV=2 8.75 1413.4 - 1.91E+06 - - - -2.9622 - 1.327 0.298 - 168.2 1 2 0 -0.0023 8 0 0 0 1.03E+08 1.18E+08 - - - 2.0946 0.9745 221125_WJC_METTL3_EV_vs_WT_F04.03811.03811.2 2.58 12-Jul K.AVANTMR.T "sp|P48643|TCPE_HUMAN,tr|E9PCA1|E9PCA1_HUMAN,tr|B7ZAR1|B7ZAR1_HUMAN,tr|E7ENZ3|E7ENZ3_HUMAN,tr|H0Y914|H0Y914_HUMAN" 5 761.3854 0.86 40950 3811 2 761.383919 381.7 T-complex protein 1 subunit epsilon OS=Homo sapiens OX=9606 GN=CCT5 PE=1 SV=1 9.79 1414.7 - 7.16E+06 - - - -1.9556 - 1.149 0.135 - 209.3 1 2 0 -0.0015 7 0 0 0 2.27E+08 2.64E+08 - - - 0.4777 0.9079 221125_WJC_METTL3_EV_vs_WT_F04.03824.03824.2 0.691 14-Jun K.LVSATTGK[136.11].V "sp|Q13685|AAMP_HUMAN,tr|H7C0R2|H7C0R2_HUMAN,tr|C9JG97|C9JG97_HUMAN,tr|C9JEH3|C9JEH3_HUMAN" 4 783.4582 0.87 40953 3824 2 783.455369 392.7364 Angio-associated migratory cell protein OS=Homo sapiens OX=9606 GN=AAMP PE=1 SV=2 8.75 1416.7 - 3.16E+06 - - - -3.5739 - 1.336 0.061 - 118.9 1 2 0 -0.0028 8 0 0 0 1.03E+08 1.18E+08 - - - 0.3643 0.9885 221125_WJC_METTL3_EV_vs_WT_F04.03835.03835.2 0.0566 14-Jul R.GGPEEGVR[166.11].G sp|Q9HCD5|NCOA5_HUMAN 1 809.3907 1.94 40954 3835 2 809.388589 405.7026 Nuclear receptor coactivator 5 OS=Homo sapiens OX=9606 GN=NCOA5 PE=1 SV=2 4.53 1418.5 - 2.50E+06 - - - -2.6094 - 1.102 0.276 - 159.3 1 2 0 -0.0021 8 0 0 0 5.40E+08 2.78E+08 - - - 1.3718 0.9744 221125_WJC_METTL3_EV_vs_WT_F04.03839.03839.2 0.297 14-Aug R.TAPVADPK[136.11].T "sp|Q15643|TRIPB_HUMAN,tr|H0YJ97|H0YJ97_HUMAN" 2 805.4425 1 40955 3839 2 805.439466 403.7285 Thyroid receptor-interacting protein 11 OS=Homo sapiens OX=9606 GN=TRIP11 PE=1 SV=3 5.5 1419 - 7.11E+06 - - - -3.7905 - 1.139 0.268 - 199.1 1 2 0 -0.0031 8 0 0 0 4.22E+08 4.20E+08 - - - 1.412 0.9883 221125_WJC_METTL3_EV_vs_WT_F04.03847.03847.2 0.0738 12-Jun K.MVPTSDK[136.11].G sp|P13639|EF2_HUMAN 1 784.388 2.14 40957 3847 2 784.385732 393.2013 Elongation factor 2 OS=Homo sapiens OX=9606 GN=EEF2 PE=1 SV=4 5.59 1420.2 - 1.14E+06 - - - -2.9424 - 1.09 0.302 - 145.2 1 2 0 -0.0023 7 0 0 0 3.52E+08 1.65E+08 - - - 1.5439 0.9896 221125_WJC_METTL3_EV_vs_WT_F04.03851.03851.2 0.208 14-Jul R.GGPEEGVR.G sp|Q9HCD5|NCOA5_HUMAN 1 799.3824 1.94 40958 3851 2 799.380402 400.6985 Nuclear receptor coactivator 5 OS=Homo sapiens OX=9606 GN=NCOA5 PE=1 SV=2 4.53 1420.8 - 8.50E+06 - - - -2.5382 - 1.125 0.273 - 176.2 1 2 0 -0.002 8 0 0 0 5.41E+08 2.78E+08 - - - 1.412 0.9409 221125_WJC_METTL3_EV_vs_WT_F04.03871.03871.2 9.41 12-Jun R.APQC[160.03]LGK[136.11].F "sp|Q00839|HNRPU_HUMAN,tr|A0A1W2PQL0|A0A1W2PQL0_HUMAN,tr|A0A1W2PPE9|A0A1W2PPE9_HUMAN,tr|A0A1W2PPL4|A0A1W2PPL4_HUMAN,tr|A0A1W2PQ74|A0A1W2PQ74_HUMAN,tr|Q5RI18|Q5RI18_HUMAN,tr|A0A1W2PP35|A0A1W2PP35_HUMAN,tr|A0A1W2PPS1|A0A1W2PPS1_HUMAN,tr|A0A1W2PRZ7|A0A1W2PRZ7_HUMAN,tr|A0A1W2PPH7|A0A1W2PPH7_HUMAN,tr|A0A1W2PQD4|A0A1W2PQD4_HUMAN,tr|A0A1W2PP34|A0A1W2PP34_HUMAN,tr|A0A1X7SBS1|A0A1X7SBS1_HUMAN" 13 780.4044 0.91 40962 3871 2 780.402631 391.2095 Heterogeneous nuclear ribonucleoprotein U OS=Homo sapiens OX=9606 GN=HNRNPU PE=1 SV=6 8.27 1423.8 - 3.57E+06 - - - -2.2142 - 1.067 0.106 - 132.6 1 2 0 -0.0017 7 0 0 0 3.65E+09 3.99E+09 - - - 0.0289 0.9927 221125_WJC_METTL3_EV_vs_WT_F04.03888.03888.2 1.27 14-Jul K.ATAEEMTK.Y "sp|Q92769|HDAC2_HUMAN,tr|E5RHE7|E5RHE7_HUMAN,tr|E5RGV4|E5RGV4_HUMAN,tr|H3BM24|H3BM24_HUMAN,tr|E5RJ04|E5RJ04_HUMAN,tr|E5RG37|E5RG37_HUMAN,tr|E5RH52|E5RH52_HUMAN,tr|E5RK19|E5RK19_HUMAN,tr|E5RFP9|E5RFP9_HUMAN,tr|E5RFI6|E5RFI6_HUMAN" 10 879.4008 1.59 40967 3888 2 879.397633 440.7077 Histone deacetylase 2 OS=Homo sapiens OX=9606 GN=HDAC2 PE=1 SV=2 4.53 1426.1 - 2.15E+06 - - - -3.582 - 1.614 0.248 - 119.1 1 2 0 -0.0032 8 0 0 0 1.08E+08 6.78E+07 - - - 2.3155 0.9937 221125_WJC_METTL3_EV_vs_WT_F04.03890.03890.2 0.201 14-Jul K.VTDTASMK.Y sp|Q6P4A8|PLBL1_HUMAN 1 851.4059 1.88 40968 3890 2 851.404369 426.7102 Phospholipase B-like 1 OS=Homo sapiens OX=9606 GN=PLBD1 PE=1 SV=2 5.81 1426.3 - 426074 - - - -1.7618 - 1.407 0.177 - 117.3 1 2 0 -0.0015 8 0 0 0 1.32E+07 7.01E+06 - - - 1.3777 0.9337 221125_WJC_METTL3_EV_vs_WT_F04.03906.03906.2 0.536 14-Jun K.ELAEAASK.W "sp|Q8NEY8|PPHLN_HUMAN,tr|B7Z8L1|B7Z8L1_HUMAN,tr|F8W6A0|F8W6A0_HUMAN,tr|F8W0Q9|F8W0Q9_HUMAN,tr|F8WF16|F8WF16_HUMAN" 5 817.4181 1.14 40971 3906 2 817.4156 409.7164 Periphilin-1 OS=Homo sapiens OX=9606 GN=PPHLN1 PE=1 SV=2 4.53 1428.7 - 2.67E+06 - - - -3.1171 - 1.168 0.136 - 112.8 2 2 0 -0.0025 8 0 0 0 3.17E+08 2.77E+08 - - - 0.3786 0.9816 221125_WJC_METTL3_EV_vs_WT_F04.03912.03912.2 3.85 12-Jun R.APQC[160.03]LGK.F "sp|Q00839|HNRPU_HUMAN,tr|A0A1W2PQL0|A0A1W2PQL0_HUMAN,tr|A0A1W2PPE9|A0A1W2PPE9_HUMAN,tr|A0A1W2PPL4|A0A1W2PPL4_HUMAN,tr|A0A1W2PQ74|A0A1W2PQ74_HUMAN,tr|Q5RI18|Q5RI18_HUMAN,tr|A0A1W2PP35|A0A1W2PP35_HUMAN,tr|A0A1W2PPS1|A0A1W2PPS1_HUMAN,tr|A0A1W2PRZ7|A0A1W2PRZ7_HUMAN,tr|A0A1W2PPH7|A0A1W2PPH7_HUMAN,tr|A0A1W2PQD4|A0A1W2PQD4_HUMAN,tr|A0A1W2PP34|A0A1W2PP34_HUMAN,tr|A0A1X7SBS1|A0A1X7SBS1_HUMAN" 13 772.3902 0.89 40972 3912 2 772.387957 387.2024 Heterogeneous nuclear ribonucleoprotein U OS=Homo sapiens OX=9606 GN=HNRNPU PE=1 SV=6 8.27 1429.6 - 5.24E+07 - - - -2.8509 - 1.108 0.242 - 144.6 1 2 0 -0.0022 7 0 0 0 3.72E+09 4.17E+09 - - - 1.1527 0.9968 221125_WJC_METTL3_EV_vs_WT_F04.03915.03915.2 0.155 14-Aug K.IQNDAGVR.L "sp|Q96I24|FUBP3_HUMAN,sp|Q92945|FUBP2_HUMAN,sp|Q96AE4|FUBP1_HUMAN,tr|M0R0I5|M0R0I5_HUMAN,tr|E9PEB5|E9PEB5_HUMAN,tr|M0R0C6|M0R0C6_HUMAN,tr|A0A087WTP3|A0A087WTP3_HUMAN" 7 871.4512 1.75 40973 3915 2 871.448548 436.7329 Far upstream element-binding protein 3 OS=Homo sapiens OX=9606 GN=FUBP3 PE=1 SV=2 5.84 1430 - 1.79E+06 - - - -3.0191 - 1.738 0.268 - 221.6 1 2 0 -0.0026 8 0 0 0 4.17E+09 2.39E+09 - - - 2.6866 0.9593 221125_WJC_METTL3_EV_vs_WT_F04.03930.03930.2 4.52 12-Jun R.LMQDDNR.G "sp|Q16706|MA2A1_HUMAN,sp|P49641|MA2A2_HUMAN,tr|H0YLU3|H0YLU3_HUMAN,tr|H0YLL4|H0YLL4_HUMAN,tr|H0YKH9|H0YKH9_HUMAN,tr|H0YLB9|H0YLB9_HUMAN" 6 890.3916 1.19 40977 3930 2 890.389885 446.2031 Alpha-mannosidase 2 OS=Homo sapiens OX=9606 GN=MAN2A1 PE=1 SV=2 4.21 1432.2 - 362937 - - - -1.9441 - 1.088 0.115 - 158.1 1 2 0 -0.0017 7 0 0 0 2.20E+07 1.84E+07 - - - 0.1571 0.9783 221125_WJC_METTL3_EV_vs_WT_F04.03936.03936.2 0.128 12-Aug K.HVVAVVK[136.11].- "sp|Q9NV06|DCA13_HUMAN,tr|A0A087WT20|A0A087WT20_HUMAN" 2 758.4894 0.001 40981 3936 2 758.486098 380.252 DDB1- and CUL4-associated factor 13 OS=Homo sapiens OX=9606 GN=DCAF13 PE=1 SV=2 8.76 1432.8 - 930736 - - - -4.3653 - 1.486 0.213 - 244.2 1 2 0 -0.0033 7 0 0 0 0.00E+00 3.92E+07 - - - 1.8682 0.9855 221125_WJC_METTL3_EV_vs_WT_F04.03937.03937.2 0.0685 12-Jun R.LMQDDNR[166.11].G "sp|Q16706|MA2A1_HUMAN,sp|P49641|MA2A2_HUMAN,tr|H0YLU3|H0YLU3_HUMAN,tr|H0YLL4|H0YLL4_HUMAN,tr|H0YKH9|H0YKH9_HUMAN,tr|H0YLB9|H0YLB9_HUMAN" 6 900.3999 1.26 40982 3937 2 900.401999 451.2072 Alpha-mannosidase 2 OS=Homo sapiens OX=9606 GN=MAN2A1 PE=1 SV=2 4.21 1432.9 - 470857 - - - 2.3467 - 1.182 0.207 - 157.4 1 2 0 0.0021 7 0 0 0 2.16E+07 1.71E+07 - - - 1.099 0.9783 221125_WJC_METTL3_EV_vs_WT_F04.03953.03953.2 1.17 12-Jul R.LSNEVSR.L "sp|Q15643|TRIPB_HUMAN,tr|G3V4R7|G3V4R7_HUMAN" 2 803.4137 0.9 40990 3953 2 803.411226 402.7141 Thyroid receptor-interacting protein 11 OS=Homo sapiens OX=9606 GN=TRIP11 PE=1 SV=3 6 1434.9 - 9.40E+06 - - - -3.1179 - 1.416 0.14 - 163.9 1 2 0 -0.0025 7 0 0 0 3.88E+08 4.33E+08 - - - 1.1764 0.9197 221125_WJC_METTL3_EV_vs_WT_F04.03957.03957.2 0.929 12-Jun R.ITPEEAK[136.11].Y sp|P62701|RS4X_HUMAN 1 794.4265 1.12 40992 3957 2 794.423533 398.2205 "40S ribosomal protein S4, X isoform OS=Homo sapiens OX=9606 GN=RPS4X PE=1 SV=2" 4.53 1435.4 - 1.33E+07 - - - -3.7776 - 1.208 0.125 - 137.6 1 2 0 -0.003 7 0 0 0 1.47E+09 1.32E+09 - - - 0.5621 0.9947 221125_WJC_METTL3_EV_vs_WT_F04.03978.03978.2 0.0381 12-Jul K.TPEEVTR.T "sp|P05089|ARGI1_HUMAN,tr|A0A5F9ZGN6|A0A5F9ZGN6_HUMAN,tr|A0A5F9ZH78|A0A5F9ZH78_HUMAN" 3 830.4134 5.99 41000 3978 2 830.411056 416.214 Arginase-1 OS=Homo sapiens OX=9606 GN=ARG1 PE=1 SV=2 4.53 1438.2 - 3.81E+06 - - - -2.8191 - 1.387 0.274 - 180.9 1 2 0 -0.0023 7 0 0 0 3.69E+08 6.16E+07 - - - 2.1006 0.8474 221125_WJC_METTL3_EV_vs_WT_F04.03983.03983.2 1.15 12-Jul R.QALEQAR.K sp|Q9BYN8|RT26_HUMAN 1 814.4297 1.8 41001 3983 2 814.426064 408.2221 "28S ribosomal protein S26, mitochondrial OS=Homo sapiens OX=9606 GN=MRPS26 PE=1 SV=1" 6 1439 - 1.14E+07 - - - -4.4841 - 1.237 0.096 - 151.2 1 2 0 -0.0037 7 0 0 0 4.41E+08 2.45E+08 - - - 0.4228 0.9637 221125_WJC_METTL3_EV_vs_WT_F04.03991.03991.2 0.498 12-Jul R.ELGETQR[166.11].R "sp|Q7L2E3|DHX30_HUMAN,tr|H7BXY3|H7BXY3_HUMAN" 2 841.4169 2.82 41006 3991 2 841.415234 421.7157 ATP-dependent RNA helicase DHX30 OS=Homo sapiens OX=9606 GN=DHX30 PE=1 SV=1 4.53 1439.9 - 1.31E+06 - - - -1.999 - 1.253 0.068 - 242 1 2 0 -0.0017 7 0 0 0 1.98E+08 7.02E+07 - - - 0.2574 0.9984 221125_WJC_METTL3_EV_vs_WT_F04.03995.03995.2 0.0839 16-Sep R.EEAVAEGAR[166.11].R sp|Q8IU81|I2BP1_HUMAN 1 940.4489 0.83 41008 3995 2 940.447706 471.2317 Interferon regulatory factor 2-binding protein 1 OS=Homo sapiens OX=9606 GN=IRF2BP1 PE=1 SV=1 4.25 1440.5 - 538215 - - - -1.3164 - 1.744 0.217 - 368.5 1 2 0 -0.0012 9 0 0 0 3.29E+07 3.98E+07 - - - 2.2524 0.9755 221125_WJC_METTL3_EV_vs_WT_F04.03996.03996.2 0.0402 14-Jun R.VTGDDSMR[166.11].M "sp|P21333|FLNA_HUMAN,tr|H7C2E7|H7C2E7_HUMAN,tr|Q60FE5|Q60FE5_HUMAN" 3 889.3839 0.46 41009 3996 2 889.381722 445.6992 Filamin-A OS=Homo sapiens OX=9606 GN=FLNA PE=1 SV=4 4.21 1440.6 - 595818 - - - -2.45 - 1.228 0.165 - 100.8 2 2 0 -0.0022 8 0 0 0 1.26E+07 2.74E+07 - - - 0.744 0.9987 221125_WJC_METTL3_EV_vs_WT_F04.04000.04000.2 0.00752 14-Jul K.AVEEMNGK[136.11].E "sp|Q13310|PABP4_HUMAN,tr|A0A7I2V5W9|A0A7I2V5W9_HUMAN,tr|B1ANR0|B1ANR0_HUMAN,tr|A0A7I2V4L7|A0A7I2V4L7_HUMAN,tr|H0YCC8|H0YCC8_HUMAN,tr|A0A7I2V598|A0A7I2V598_HUMAN,tr|H0Y5F5|H0Y5F5_HUMAN" 7 884.4153 1.38 41011 4000 2 884.413703 443.2149 Polyadenylate-binding protein 4 OS=Homo sapiens OX=9606 GN=PABPC4 PE=1 SV=1 4.53 1441.1 - 1.37E+06 - - - -1.8261 - 1.293 0.395 - 155.6 1 2 0 -0.0016 8 0 0 0 6.07E+07 4.41E+07 - - - 2.733 0.8525 221125_WJC_METTL3_EV_vs_WT_F04.04019.04019.2 0.489 14-Jun R.VTGDDSMR[166.11].M "sp|P21333|FLNA_HUMAN,tr|H7C2E7|H7C2E7_HUMAN,tr|Q60FE5|Q60FE5_HUMAN" 3 889.3839 0.46 41018 4019 2 889.387292 445.6992 Filamin-A OS=Homo sapiens OX=9606 GN=FLNA PE=1 SV=4 4.21 1443.6 - 460474 - - - 3.8128 - 0.904 0.191 - 79.7 1 2 0 0.0034 8 0 0 0 1.26E+07 2.74E+07 - - - 0.1463 0.9151 221125_WJC_METTL3_EV_vs_WT_F04.04021.04021.2 4.68 14-May K.ELAQEQAR[166.11].R sp|Q15149|PLEC_HUMAN 1 953.4806 1.19 41020 4021 2 953.480098 477.7476 Plectin OS=Homo sapiens OX=9606 GN=PLEC PE=1 SV=3 4.53 1443.9 - 584411 - - - -0.5045 - 1.052 0.056 - 55.2 7 2 0 -0.0005 8 0 0 0 7.11E+06 5.98E+06 - - - -0.7702 0.8995 221125_WJC_METTL3_EV_vs_WT_F04.04039.04039.2 0.336 12-Jul L.VLTEEEK[136.11].R "sp|Q70SY1|CR3L2_HUMAN,sp|P26373|RL13_HUMAN,tr|H3BUK8|H3BUK8_HUMAN,tr|J3KS98|J3KS98_HUMAN" 4 854.4477 1.09 41027 4039 2 854.447054 428.2311 Cyclic AMP-responsive element-binding protein 3-like protein 2 OS=Homo sapiens OX=9606 GN=CREB3L2 PE=1 SV=3 4.25 1446.2 - 1.38E+07 - - - -0.7139 - 1.385 0.249 - 184.2 1 1 0 -0.0006 7 0 0 0 5.05E+08 4.65E+08 - - - 1.9119 0.9972 221125_WJC_METTL3_EV_vs_WT_F04.04045.04045.2 0.386 12-Jul K.ANEVISK[136.11].L "sp|P50990|TCPQ_HUMAN,tr|H7C2U0|H7C2U0_HUMAN" 2 767.4269 0.39 41028 4045 2 767.425803 384.7207 T-complex protein 1 subunit theta OS=Homo sapiens OX=9606 GN=CCT8 PE=1 SV=4 6.05 1447.2 - 2.59E+06 - - - -1.3891 - 1.615 0.169 - 339.7 1 2 0 -0.0011 7 0 0 0 5.02E+08 1.29E+09 - - - 1.8077 0.9741 221125_WJC_METTL3_EV_vs_WT_F04.04050.04050.2 0.162 14-Aug K.SEVAAGVK.K sp|Q01780|EXOSX_HUMAN 1 759.4127 0.38 41030 4050 2 759.410494 380.7136 Exosome component 10 OS=Homo sapiens OX=9606 GN=EXOSC10 PE=1 SV=2 5.72 1447.8 - 1.83E+06 - - - -2.8641 - 1.519 0.101 - 140.3 2 2 0 -0.0022 8 0 0 0 4.89E+08 1.27E+09 - - - 0.9127 0.9904 221125_WJC_METTL3_EV_vs_WT_F04.04056.04056.2 0.0566 12-May K.LTSDDVK[136.11].E "sp|P62277|RS13_HUMAN,sp|Q15751|HERC1_HUMAN,tr|J3KMX5|J3KMX5_HUMAN,tr|H0YK45|H0YK45_HUMAN,tr|E9PS50|E9PS50_HUMAN" 5 784.4058 0.91 41034 4056 2 784.403898 393.2102 40S ribosomal protein S13 OS=Homo sapiens OX=9606 GN=RPS13 PE=1 SV=2 4.21 1448.5 - 4.79E+06 - - - -2.4235 - 1.385 0.18 - 66.5 1 2 0 -0.0019 7 0 0 0 1.36E+09 1.49E+09 - - - 1.4019 0.9949 221125_WJC_METTL3_EV_vs_WT_F04.04059.04059.2 0.00993 12-Jul K.LTSDDVK.E "sp|P62277|RS13_HUMAN,sp|Q15751|HERC1_HUMAN,tr|J3KMX5|J3KMX5_HUMAN,tr|H0YK45|H0YK45_HUMAN,tr|E9PS50|E9PS50_HUMAN" 5 776.3916 0.88 41035 4059 2 776.390272 389.2031 40S ribosomal protein S13 OS=Homo sapiens OX=9606 GN=RPS13 PE=1 SV=2 4.21 1448.9 - 6.32E+06 - - - -1.7092 - 1.608 0.13 - 168.8 1 2 0 -0.0013 7 0 0 0 1.36E+09 1.53E+09 - - - 1.5058 0.7705 221125_WJC_METTL3_EV_vs_WT_F04.04063.04063.2 1.09 12-Jul R.VLEEEQK[136.11].L "sp|O75208|COQ9_HUMAN,tr|H3BPY0|H3BPY0_HUMAN,tr|H3BPC6|H3BPC6_HUMAN,tr|H3BSJ5|H3BSJ5_HUMAN,tr|H3BNT2|H3BNT2_HUMAN" 5 881.4586 1.2 41037 4063 2 882.461128 441.7366 "Ubiquinone biosynthesis protein COQ9, mitochondrial OS=Homo sapiens OX=9606 GN=COQ9 PE=1 SV=1" 4.25 1449.4 - 1.35E+06 - - - 1137.3932 - 1.292 0.19 - 171.4 1 2 0 1.0026 7 0 0 0 6.12E+07 5.09E+07 - - - 0.9413 0.9884 221125_WJC_METTL3_EV_vs_WT_F04.04065.04065.2 0.182 12-Jul R.EVQTAVR.L "sp|Q8N257|H2B3B_HUMAN,sp|A0A2R8Y619|H2BE1_HUMAN" 2 801.4345 0.97 41038 4065 2 801.43405 401.7245 Histone H2B type 3-B OS=Homo sapiens OX=9606 GN=H2BU1 PE=1 SV=3 6.1 1449.6 - 3.02E+06 - - - -0.5203 - 1.288 0.094 - 284.4 1 2 0 -0.0004 7 0 0 0 3.28E+08 3.37E+08 - - - 0.5371 0.9937 221125_WJC_METTL3_EV_vs_WT_F04.04066.04066.2 1.22 12-Jul R.VLEEEQK[136.11].L "sp|O75208|COQ9_HUMAN,tr|H3BPY0|H3BPY0_HUMAN,tr|H3BPC6|H3BPC6_HUMAN,tr|H3BSJ5|H3BSJ5_HUMAN,tr|H3BNT2|H3BNT2_HUMAN" 5 881.4586 1.2 41039 4066 2 881.457526 441.7366 "Ubiquinone biosynthesis protein COQ9, mitochondrial OS=Homo sapiens OX=9606 GN=COQ9 PE=1 SV=1" 4.25 1449.7 - 1.33E+06 - - - -1.1765 - 1.258 0.184 - 159 1 2 0 -0.001 7 0 0 0 6.12E+07 5.09E+07 - - - 1.127 0.9963 221125_WJC_METTL3_EV_vs_WT_F04.04077.04077.2 0.129 12-Jul K.IISEC[160.03]SK.E sp|O94826|TOM70_HUMAN 1 835.411 1.59 41043 4077 2 835.40951 418.7128 Mitochondrial import receptor subunit TOM70 OS=Homo sapiens OX=9606 GN=TOMM70 PE=1 SV=1 5.99 1451.3 - 802282 - - - -1.7285 - 1.385 0.228 - 147.6 1 2 0 -0.0014 7 0 0 0 3.05E+07 1.92E+07 - - - 1.7566 0.999 221125_WJC_METTL3_EV_vs_WT_F04.04081.04081.2 0.000986 14-Jul K.AVDEMNGK.E "sp|Q9H361|PABP3_HUMAN,sp|P11940|PABP1_HUMAN,tr|A0A7I2YQE4|A0A7I2YQE4_HUMAN,tr|H0YAR2|H0YAR2_HUMAN,tr|E7ERJ7|E7ERJ7_HUMAN,tr|A0A7I2YQ88|A0A7I2YQ88_HUMAN,tr|A0A087WTT1|A0A087WTT1_HUMAN,tr|H0YAP2|H0YAP2_HUMAN,tr|A0A7I2YQ90|A0A7I2YQ90_HUMAN,tr|A0A7I2V4N4|A0A7I2V4N4_HUMAN,tr|E7EQV3|E7EQV3_HUMAN" 11 862.3855 1.15 41045 4081 2 862.384028 432.2 Polyadenylate-binding protein 3 OS=Homo sapiens OX=9606 GN=PABPC3 PE=1 SV=2 4.37 1451.7 - 5.03E+06 - - - -1.6698 - 1.429 0.38 - 146.3 1 2 0 -0.0014 8 0 0 0 4.13E+08 3.60E+08 - - - 2.9238 0.999 221125_WJC_METTL3_EV_vs_WT_F04.04085.04085.2 0.00475 14-Jul K.AVDEMNGK[136.11].E "sp|Q9H361|PABP3_HUMAN,sp|P11940|PABP1_HUMAN,tr|A0A7I2YQE4|A0A7I2YQE4_HUMAN,tr|H0YAR2|H0YAR2_HUMAN,tr|E7ERJ7|E7ERJ7_HUMAN,tr|A0A7I2YQ88|A0A7I2YQ88_HUMAN,tr|A0A087WTT1|A0A087WTT1_HUMAN,tr|H0YAP2|H0YAP2_HUMAN,tr|A0A7I2YQ90|A0A7I2YQ90_HUMAN,tr|A0A7I2V4N4|A0A7I2V4N4_HUMAN,tr|E7EQV3|E7EQV3_HUMAN" 11 870.3997 1.18 41046 4085 2 870.39785 436.2071 Polyadenylate-binding protein 3 OS=Homo sapiens OX=9606 GN=PABPC3 PE=1 SV=2 4.37 1452.3 - 5.54E+06 - - - -2.0887 - 1.239 0.477 - 135.6 1 2 0 -0.0018 8 0 0 0 4.13E+08 3.49E+08 - - - 3.2099 0.9916 221125_WJC_METTL3_EV_vs_WT_F04.04089.04089.2 0.886 14-Jul K.ALSEAQAR.F "sp|Q16513|PKN2_HUMAN,tr|H0Y5V5|H0Y5V5_HUMAN,tr|B1AL79|B1AL79_HUMAN" 3 844.4403 0.14 41047 4089 2 844.438215 423.2274 Serine\threonine-protein kinase N2 OS=Homo sapiens OX=9606 GN=PKN2 PE=1 SV=1 6.05 1452.9 - 1.47E+06 - - - -2.4454 - 1.287 0.233 - 141 1 2 0 -0.0021 8 0 0 0 6.25E+07 4.62E+08 - - - 1.5223 0.997 221125_WJC_METTL3_EV_vs_WT_F04.04095.04095.2 0.0322 16-Aug R.AGPGVGEAR[166.11].L sp|Q9H0W5|CCDC8_HUMAN 1 822.4223 1.47 41048 4095 2 822.424064 412.2184 Coiled-coil domain-containing protein 8 OS=Homo sapiens OX=9606 GN=CCDC8 PE=1 SV=2 6.05 1453.8 - 1.87E+06 - - - 2.1011 - 1.502 0.27 - 223.5 1 2 0 0.0017 9 0 0 0 1.02E+08 6.96E+07 - - - 2.2116 0.9985 221125_WJC_METTL3_EV_vs_WT_F04.04122.04122.2 0.00129 14-Jul K.IISTTASK.T sp|O95292|VAPB_HUMAN 1 819.4702 1.15 41059 4122 2 819.469565 410.7424 Vesicle-associated membrane protein-associated protein B\C OS=Homo sapiens OX=9606 GN=VAPB PE=1 SV=3 8.75 1457.3 - 2.48E+06 - - - -0.7541 - 1.505 0.245 - 115.9 1 2 0 -0.0006 8 0 0 0 1.77E+08 1.54E+08 - - - 2.0833 0.9992 221125_WJC_METTL3_EV_vs_WT_F04.04151.04151.2 0.0157 14-Aug R.STASALTK[136.11].L sp|Q7Z6Z7|HUWE1_HUMAN 1 785.4374 0.41 41072 4151 2 785.436594 393.726 E3 ubiquitin-protein ligase HUWE1 OS=Homo sapiens OX=9606 GN=HUWE1 PE=1 SV=3 8.47 1461.1 - 991941 - - - -1.0682 - 1.64 0.301 - 227.3 1 2 0 -0.0008 8 0 0 0 1.49E+07 3.62E+07 - - - 2.7559 0.996 221125_WJC_METTL3_EV_vs_WT_F04.04159.04159.2 0.278 12-Jul K.MEVASEK[136.11].K sp|Q9UKX7|NUP50_HUMAN 1 800.383 1.24 41076 4159 2 800.382701 401.1988 Nuclear pore complex protein Nup50 OS=Homo sapiens OX=9606 GN=NUP50 PE=1 SV=2 4.53 1462.2 - 1.36E+06 - - - -0.3173 - 1.55 0.113 - 230.3 1 2 0 -0.0003 7 0 0 0 5.98E+07 4.83E+07 - - - 1.2642 0.998 221125_WJC_METTL3_EV_vs_WT_F04.04161.04161.2 0.264 12-Aug K.IQSTPVK[136.11].Q "sp|P62820|RAB1A_HUMAN,tr|E7END7|E7END7_HUMAN" 2 779.4633 1.08 41077 4161 2 779.461686 390.7389 Ras-related protein Rab-1A OS=Homo sapiens OX=9606 GN=RAB1A PE=1 SV=3 8.75 1462.4 - 9.43E+06 - - - -2.0116 - 1.666 0.239 - 176.1 1 2 0 -0.0016 7 0 0 0 3.58E+08 3.30E+08 - - - 2.4231 0.9984 221125_WJC_METTL3_EV_vs_WT_F04.04166.04166.2 0.409 12-Jun K.IQSTPVK.Q "sp|P62820|RAB1A_HUMAN,tr|E7END7|E7END7_HUMAN" 2 771.4491 1.08 41078 4166 2 771.448332 386.7318 Ras-related protein Rab-1A OS=Homo sapiens OX=9606 GN=RAB1A PE=1 SV=3 8.75 1463.2 - 1.04E+07 - - - -0.9359 - 1.451 0.254 - 102.5 1 2 0 -0.0007 7 0 0 0 3.58E+08 3.30E+08 - - - 2.0963 0.98 221125_WJC_METTL3_EV_vs_WT_F04.04170.04170.2 1.01 16-Jun R.K[136.11]ASGEVADK[136.11].L "sp|Q9BWF2|TRAIP_HUMAN,tr|E7EN91|E7EN91_HUMAN" 2 919.4946 0.39 41080 4170 2 919.494617 460.7546 E3 ubiquitin-protein ligase TRAIP OS=Homo sapiens OX=9606 GN=TRAIP PE=1 SV=1 6.07 1463.7 - 371907 - - - 0.0609 - 1.354 0.069 - 153.7 4 2 0 0.0001 9 0 0 0 3.71E+06 9.40E+06 - - - 0.1585 0.999 221125_WJC_METTL3_EV_vs_WT_F04.04175.04175.2 1.58 14-Jul R.LSAEAAEK.L "sp|P33992|MCM5_HUMAN,tr|B1AHB1|B1AHB1_HUMAN" 2 817.4181 0.56 41081 4175 2 817.41802 409.7164 DNA replication licensing factor MCM5 OS=Homo sapiens OX=9606 GN=MCM5 PE=1 SV=5 4.53 1464.5 - 2.19E+06 - - - -0.1566 - 1.676 0.234 - 122 1 2 0 -0.0001 8 0 0 0 6.60E+07 1.17E+08 - - - 2.3268 0.9992 221125_WJC_METTL3_EV_vs_WT_F04.04178.04178.2 0.00247 14-Sep K.FASEAEDK[136.11].L "sp|Q9P2J5|SYLC_HUMAN,tr|A0A6I8PIV1|A0A6I8PIV1_HUMAN,tr|A0A6I8PRS0|A0A6I8PRS0_HUMAN,tr|A0A6I8PLB8|A0A6I8PLB8_HUMAN,tr|A0A6I8PIT3|A0A6I8PIT3_HUMAN,tr|A0A6I8PLB3|A0A6I8PLB3_HUMAN,tr|A0A6I8PS05|A0A6I8PS05_HUMAN,tr|B4DER1|B4DER1_HUMAN,tr|A0A6I8PL42|A0A6I8PL42_HUMAN" 9 903.4065 1.18 41082 4178 2 903.406048 452.7105 "Leucine--tRNA ligase, cytoplasmic OS=Homo sapiens OX=9606 GN=LARS1 PE=1 SV=2" 4.14 1464.9 - 590405 - - - -0.5302 - 1.476 0.33 - 198.1 1 2 0 -0.0005 8 0 0 0 2.42E+07 2.06E+07 - - - 2.6524 0.9707 221125_WJC_METTL3_EV_vs_WT_F04.04181.04181.2 2.12 12-Jun K.QVSNIGR[166.11].K sp|Q9UJV9|DDX41_HUMAN 1 782.4274 0.9 41083 4181 2 782.425964 392.221 Probable ATP-dependent RNA helicase DDX41 OS=Homo sapiens OX=9606 GN=DDX41 PE=1 SV=2 9.75 1465.4 - 2.13E+06 - - - -1.8622 - 1.116 0.129 - 167.5 1 2 0 -0.0015 7 0 0 0 7.19E+07 7.98E+07 - - - 0.3411 0.9994 221125_WJC_METTL3_EV_vs_WT_F04.04183.04183.2 0.0171 14-Aug K.FASEAEDK.L "sp|Q9P2J5|SYLC_HUMAN,tr|A0A6I8PIV1|A0A6I8PIV1_HUMAN,tr|A0A6I8PRS0|A0A6I8PRS0_HUMAN,tr|A0A6I8PLB8|A0A6I8PLB8_HUMAN,tr|A0A6I8PIT3|A0A6I8PIT3_HUMAN,tr|A0A6I8PLB3|A0A6I8PLB3_HUMAN,tr|A0A6I8PS05|A0A6I8PS05_HUMAN,tr|B4DER1|B4DER1_HUMAN,tr|A0A6I8PL42|A0A6I8PL42_HUMAN" 9 895.3923 1.13 41084 4183 2 895.391834 448.7034 "Leucine--tRNA ligase, cytoplasmic OS=Homo sapiens OX=9606 GN=LARS1 PE=1 SV=2" 4.14 1465.6 - 1.16E+06 - - - -0.5506 - 1.501 0.359 - 159.4 1 2 0 -0.0005 8 0 0 0 2.44E+07 2.15E+07 - - - 2.9173 0.9944 221125_WJC_METTL3_EV_vs_WT_F04.04188.04188.2 0.274 16-Sep K.VTGSLSSAK[136.11].R sp|P39748|FEN1_HUMAN 1 856.4745 0.44 41087 4188 2 856.473701 429.2445 Flap endonuclease 1 OS=Homo sapiens OX=9606 GN=FEN1 PE=1 SV=1 8.72 1466.3 - 2.51E+06 - - - -0.9878 - 1.176 0.221 - 169.8 1 2 0 -0.0008 9 0 0 0 2.72E+07 6.23E+07 - - - 1.1421 0.9991 221125_WJC_METTL3_EV_vs_WT_F04.04190.04190.2 0.0827 14-Jul R.AVPTDEAR.A "sp|Q15907|RB11B_HUMAN,sp|P62491|RB11A_HUMAN,tr|B4DQU5|B4DQU5_HUMAN,tr|H3BMH2|H3BMH2_HUMAN,tr|H3BSC1|H3BSC1_HUMAN,tr|M0R2D0|M0R2D0_HUMAN,tr|H3BN38|H3BN38_HUMAN,tr|M0R377|M0R377_HUMAN" 8 857.4243 0.98 41089 4190 2 857.423901 429.7194 Ras-related protein Rab-11B OS=Homo sapiens OX=9606 GN=RAB11B PE=1 SV=4 4.37 1466.4 - 2.51E+06 - - - -0.4607 - 1.429 0.314 - 174.1 1 2 0 -0.0004 8 0 0 0 5.07E+08 5.19E+08 - - - 2.4367 0.9955 221125_WJC_METTL3_EV_vs_WT_F04.04195.04195.2 0.179 12-Jun R.FVQSC[160.03]AR[166.11].A sp|P36551|HEM6_HUMAN 1 876.4151 0.47 41092 4195 2 876.413597 439.2148 "Oxygen-dependent coproporphyrinogen-III oxidase, mitochondrial OS=Homo sapiens OX=9606 GN=CPOX PE=1 SV=3" 8.25 1467 - 906777 - - - -1.7629 - 1.089 0.313 - 143.6 1 2 0 -0.0015 7 0 0 0 1.15E+07 2.43E+07 - - - 1.6225 0.9989 221125_WJC_METTL3_EV_vs_WT_F04.04202.04202.2 0.917 14-Jul R.AVPTDEAR[166.11].A "sp|Q15907|RB11B_HUMAN,sp|P62491|RB11A_HUMAN,tr|B4DQU5|B4DQU5_HUMAN,tr|H3BMH2|H3BMH2_HUMAN,tr|H3BSC1|H3BSC1_HUMAN,tr|M0R2D0|M0R2D0_HUMAN,tr|H3BN38|H3BN38_HUMAN,tr|M0R377|M0R377_HUMAN" 8 867.4326 1.16 41094 4202 2 867.433123 434.7236 Ras-related protein Rab-11B OS=Homo sapiens OX=9606 GN=RAB11B PE=1 SV=4 4.37 1468 - 3.15E+06 - - - 0.6421 - 1.462 0.295 - 209.7 1 2 0 0.0006 8 0 0 0 4.74E+08 4.10E+08 - - - 2.3652 0.999 221125_WJC_METTL3_EV_vs_WT_F04.04204.04204.2 0.0842 14-Oct R.TGQAVAVR.A sp|P56545|CTBP2_HUMAN 1 800.4505 0.7 41095 4204 2 800.450457 401.2325 C-terminal-binding protein 2 OS=Homo sapiens OX=9606 GN=CTBP2 PE=1 SV=1 9.41 1468.2 - 719124 - - - 0.0075 - 1.976 0.176 - 511.8 1 2 0 0 8 0 0 0 2.78E+07 3.99E+07 - - - 2.395 0.9932 221125_WJC_METTL3_EV_vs_WT_F04.04214.04214.2 2.14E-05 22-Dec R.PATAAAAAAGSR[166.11].E "sp|Q7Z478|DHX29_HUMAN,tr|A0A087WYN9|A0A087WYN9_HUMAN" 2 1023.5337 0.5 41101 4214 2 1023.534176 512.7741 ATP-dependent RNA helicase DHX29 OS=Homo sapiens OX=9606 GN=DHX29 PE=1 SV=2 10.18 1469.6 - 162780 - - - 0.4875 - 2.285 0.529 - 244.9 1 1 0 0.0005 12 0 0 0 2.25E+06 4.47E+06 - - - 5.1223 0.9993 221125_WJC_METTL3_EV_vs_WT_F04.04240.04240.2 0.00414 18-Nov R.IAGQVAAANK.K "sp|P39019|RS19_HUMAN,tr|A0A075B6E2|A0A075B6E2_HUMAN" 2 941.5294 1.18 41106 4240 2 941.529226 471.772 40S ribosomal protein S19 OS=Homo sapiens OX=9606 GN=RPS19 PE=1 SV=2 8.75 1473.6 - 2.64E+06 - - - -0.2167 - 1.746 0.288 - 287.3 1 2 0 -0.0002 10 0 0 0 5.38E+09 4.54E+09 - - - 2.7238 0.9978 221125_WJC_METTL3_EV_vs_WT_F04.04241.04241.2 0.472 12-Sep K.EQAAQLR.N "sp|P40938|RFC3_HUMAN,sp|Q86UW7|CAPS2_HUMAN,sp|Q9ULU8|CAPS1_HUMAN,tr|F8W8P5|F8W8P5_HUMAN,tr|A0A087X1P3|A0A087X1P3_HUMAN,tr|C9IYE1|C9IYE1_HUMAN,tr|F1T0E5|F1T0E5_HUMAN" 7 814.4297 1.03 41107 4241 2 814.42968 408.2221 Replication factor C subunit 3 OS=Homo sapiens OX=9606 GN=RFC3 PE=1 SV=2 6.1 1473.7 - 1.31E+06 - - - -0.0442 - 1.636 0.149 - 448.3 1 2 0 0 7 0 0 0 5.50E+07 5.36E+07 - - - 1.7012 0.9995 221125_WJC_METTL3_EV_vs_WT_F04.04242.04242.2 0.00443 12-Jul K.VDEEQMK.Y sp|P13010|XRCC5_HUMAN 1 877.3851 1.2 41108 4242 2 877.384167 439.6998 X-ray repair cross-complementing protein 5 OS=Homo sapiens OX=9606 GN=XRCC5 PE=1 SV=3 4.14 1473.8 - 776004 - - - -1.101 - 1.57 0.389 - 132.3 1 2 0 -0.001 7 0 0 0 9.96E+07 8.31E+07 - - - 3.3431 0.9959 221125_WJC_METTL3_EV_vs_WT_F04.04255.04255.2 0.0586 12-Jul K.VDEEQMK[136.11].Y sp|P13010|XRCC5_HUMAN 1 885.3993 1.22 41115 4255 2 885.398263 443.7069 X-ray repair cross-complementing protein 5 OS=Homo sapiens OX=9606 GN=XRCC5 PE=1 SV=3 4.14 1475.4 - 2.49E+06 - - - -1.2085 - 1.174 0.258 - 125.8 1 2 0 -0.0011 7 0 0 0 9.41E+07 7.71E+07 - - - 1.4545 0.9951 221125_WJC_METTL3_EV_vs_WT_F04.04262.04262.2 2.08 12-Jul R.FTDEESR.V "sp|Q9NYF8|BCLF1_HUMAN,tr|H0YF00|H0YF00_HUMAN,tr|E9PKI6|E9PKI6_HUMAN,tr|A0A1W2PQ43|A0A1W2PQ43_HUMAN,tr|E9PK91|E9PK91_HUMAN,tr|E9PK09|E9PK09_HUMAN,tr|E9PQN2|E9PQN2_HUMAN" 7 882.3719 2.18 41117 4262 2 882.369991 442.1932 Bcl-2-associated transcription factor 1 OS=Homo sapiens OX=9606 GN=BCLAF1 PE=1 SV=2 4.14 1476.4 - 4.06E+06 - - - -2.193 - 1.333 0.249 - 173.3 1 2 0 -0.0019 7 0 0 0 6.32E+08 2.89E+08 - - - 1.7903 0.9892 221125_WJC_METTL3_EV_vs_WT_F04.04271.04271.2 0.524 12-Aug R.AAAEQLR[166.11].Q "sp|O94766|B3GA3_HUMAN,tr|G3V150|G3V150_HUMAN,tr|E9PNA1|E9PNA1_HUMAN" 3 767.4165 0.55 41120 4271 2 767.414522 384.7155 Galactosylgalactosylxylosylprotein 3-beta-glucuronosyltransferase 3 OS=Homo sapiens OX=9606 GN=B3GAT3 PE=1 SV=2 6.05 1477.6 - 2.20E+06 - - - -2.6061 - 1.635 0.111 - 324.7 1 2 0 -0.002 7 0 0 0 1.75E+08 3.16E+08 - - - 1.418 0.9951 221125_WJC_METTL3_EV_vs_WT_F04.04279.04279.2 3.21 12-Jul R.FTDEESR[166.11].V "sp|Q9NYF8|BCLF1_HUMAN,tr|H0YF00|H0YF00_HUMAN,tr|E9PKI6|E9PKI6_HUMAN,tr|A0A1W2PQ43|A0A1W2PQ43_HUMAN,tr|E9PK91|E9PK91_HUMAN,tr|E9PK09|E9PK09_HUMAN,tr|E9PQN2|E9PQN2_HUMAN" 7 892.3802 2.18 41124 4279 2 892.377844 447.1974 Bcl-2-associated transcription factor 1 OS=Homo sapiens OX=9606 GN=BCLAF1 PE=1 SV=2 4.14 1478.4 - 9.36E+06 - - - -2.6356 - 1.462 0.246 - 162.8 1 2 0 -0.0024 7 0 0 0 6.32E+08 2.90E+08 - - - 2.0607 0.962 221125_WJC_METTL3_EV_vs_WT_F04.04280.04280.2 0.317 12-Jun R.FTEAGER[166.11].V "sp|Q96A35|RM24_HUMAN,tr|X6RJ73|X6RJ73_HUMAN" 2 818.3798 1.92 41125 4280 2 818.376456 410.1972 "39S ribosomal protein L24, mitochondrial OS=Homo sapiens OX=9606 GN=MRPL24 PE=1 SV=1" 4.53 1478.5 - 1.20E+06 - - - -4.0886 - 1.293 0.192 - 130.5 1 2 0 -0.0033 7 0 0 0 1.01E+08 5.24E+07 - - - 1.2723 0.9159 221125_WJC_METTL3_EV_vs_WT_F04.04285.04285.2 0.366 12-May R.FTEAGER.V "sp|Q96A35|RM24_HUMAN,tr|X6RJ73|X6RJ73_HUMAN" 2 808.3715 1.55 41127 4285 2 808.368348 405.193 "39S ribosomal protein L24, mitochondrial OS=Homo sapiens OX=9606 GN=MRPL24 PE=1 SV=1" 4.53 1479.1 - 2.19E+06 - - - -3.9388 - 1.076 0.199 - 71.1 2 2 0 -0.0032 7 0 0 0 7.59E+07 4.90E+07 - - - 0.6074 0.9991 221125_WJC_METTL3_EV_vs_WT_F04.04291.04291.2 0.0186 14-Oct K.C[160.03]LSAAEEK.Y "tr|A0A2R2Y2Q3|A0A2R2Y2Q3_HUMAN,tr|A0A087WWU8|A0A087WWU8_HUMAN,tr|J3KN67|J3KN67_HUMAN,tr|A0A494C0P6|A0A494C0P6_HUMAN" 4 906.4117 1.14 41130 4291 2 906.410989 454.2131 Tropomyosin 3 nu OS=Homo sapiens OX=9606 GN=TPM3 PE=1 SV=1 4.53 1479.8 - 644053 - - - -0.7657 - 1.371 0.347 - 323.4 1 2 0 -0.0007 8 0 0 0 6.89E+07 6.06E+07 - - - 2.5554 0.8956 221125_WJC_METTL3_EV_vs_WT_F04.04294.04294.2 4.81 12-May R.GMPQEER.L "sp|Q13838|DX39B_HUMAN,tr|H0Y400|H0Y400_HUMAN,tr|Q5STU3|Q5STU3_HUMAN,tr|A0A0G2JJZ9|A0A0G2JJZ9_HUMAN,tr|A0A140T9X3|A0A140T9X3_HUMAN" 5 845.3702 1.29 41131 4294 2 845.367449 423.6924 Spliceosome RNA helicase DDX39B OS=Homo sapiens OX=9606 GN=DDX39B PE=1 SV=1 4.53 1480.2 - 2.41E+06 - - - -3.1974 - 0.917 0.18 - 75.8 1 2 0 -0.0027 7 0 0 0 7.54E+07 5.86E+07 - - - 0.0951 0.9991 221125_WJC_METTL3_EV_vs_WT_F04.04295.04295.2 0.00463 14-Oct K.C[160.03]LSAAEEK[136.11].Y "tr|A0A2R2Y2Q3|A0A2R2Y2Q3_HUMAN,tr|A0A087WWU8|A0A087WWU8_HUMAN,tr|J3KN67|J3KN67_HUMAN,tr|A0A494C0P6|A0A494C0P6_HUMAN" 4 914.4259 1.14 41132 4295 2 914.423267 458.2202 Tropomyosin 3 nu OS=Homo sapiens OX=9606 GN=TPM3 PE=1 SV=1 4.53 1480.3 - 901850 - - - -2.8608 - 2.048 0.373 - 327.7 1 2 0 -0.0026 8 0 0 0 6.89E+07 6.06E+07 - - - 3.9572 0.9899 221125_WJC_METTL3_EV_vs_WT_F04.04303.04303.2 0.00739 12-Jul R.MGQTMER[166.11].L "sp|P52272|HNRPM_HUMAN,tr|A0A087X0X3|A0A087X0X3_HUMAN,tr|M0QZM1|M0QZM1_HUMAN" 3 861.3712 1.53 41136 4303 2 861.366651 431.6929 Heterogeneous nuclear ribonucleoprotein M OS=Homo sapiens OX=9606 GN=HNRNPM PE=1 SV=3 5.75 1481.3 - 2.66E+06 - - - -5.3136 - 1.519 0.383 - 180.2 1 2 0 -0.0046 7 0 0 0 5.35E+08 3.51E+08 - - - 3.193 0.9939 221125_WJC_METTL3_EV_vs_WT_F04.04305.04305.2 0.0454 12-Jul K.TLSEETR.Q "sp|Q5T9A4|ATD3B_HUMAN,sp|Q9NVI7|ATD3A_HUMAN,tr|H0Y2W2|H0Y2W2_HUMAN" 3 834.4083 1.81 41137 4305 2 834.406134 418.2114 ATPase family AAA domain-containing protein 3B OS=Homo sapiens OX=9606 GN=ATAD3B PE=1 SV=1 4.53 1481.5 - 4.52E+06 - - - -2.609 - 1.258 0.284 - 215.1 1 2 0 -0.0022 7 0 0 0 2.10E+08 1.16E+08 - - - 1.8652 0.9966 221125_WJC_METTL3_EV_vs_WT_F04.04309.04309.2 0.0451 14-Jul R.ADAENAMR.Y "sp|P52298|NCBP2_HUMAN,sp|A6PVI3|NCB2L_HUMAN,tr|C9JQX9|C9JQX9_HUMAN,tr|B3KSB0|B3KSB0_HUMAN" 4 876.376 3.08 41140 4309 2 876.375781 439.1953 Nuclear cap-binding protein subunit 2 OS=Homo sapiens OX=9606 GN=NCBP2 PE=1 SV=1 4.37 1481.9 - 1.13E+06 - - - -0.21 - 1.304 0.208 - 183.9 1 2 0 -0.0002 8 0 0 0 7.15E+07 2.32E+07 - - - 1.3778 0.9991 221125_WJC_METTL3_EV_vs_WT_F04.04321.04321.2 0.0838 12-Aug R.MGQTMER.L "sp|P52272|HNRPM_HUMAN,tr|A0A087X0X3|A0A087X0X3_HUMAN,tr|M0QZM1|M0QZM1_HUMAN" 3 851.363 1.53 41143 4321 2 851.361288 426.6888 Heterogeneous nuclear ribonucleoprotein M OS=Homo sapiens OX=9606 GN=HNRNPM PE=1 SV=3 5.75 1483.7 - 2.09E+07 - - - -1.9616 - 1.62 0.354 - 243.5 1 2 0 -0.0017 7 0 0 0 5.36E+08 3.51E+08 - - - 3.1837 0.9749 221125_WJC_METTL3_EV_vs_WT_F04.04323.04323.2 0.782 14-Jul R.EGNAVAVR[166.11].L "sp|Q13418|ILK_HUMAN,tr|A0A087WWY6|A0A087WWY6_HUMAN,tr|A0A0A0MTH3|A0A0A0MTH3_HUMAN,tr|A0A087WW45|A0A087WW45_HUMAN,tr|E9PQ52|E9PQ52_HUMAN" 5 824.438 0.32 41144 4323 2 824.437495 413.2263 Integrin-linked protein kinase OS=Homo sapiens OX=9606 GN=ILK PE=1 SV=2 6.1 1483.9 - 3.28E+06 - - - -0.5956 - 1.393 0.018 - 169.4 2 2 0 -0.0005 8 0 0 0 3.40E+07 1.05E+08 - - - 0.039 0.9586 221125_WJC_METTL3_EV_vs_WT_F04.04326.04326.2 1.29 12-Jun R.VIQQSVR[166.11].T "sp|Q92974|ARHG2_HUMAN,tr|A0A5F9ZI21|A0A5F9ZI21_HUMAN,tr|V9GYM8|V9GYM8_HUMAN" 3 838.49 0.45 41147 4326 2 838.490486 420.2523 Rho guanine nucleotide exchange factor 2 OS=Homo sapiens OX=9606 GN=ARHGEF2 PE=1 SV=4 9.72 1484.1 - 872191 - - - 0.5546 - 1.29 0.005 - 129.1 2 2 0 0.0005 7 0 0 0 1.97E+07 4.40E+07 - - - -0.2498 0.9496 221125_WJC_METTL3_EV_vs_WT_F04.04330.04330.2 2.45 12-Jul K.SVIENAK.K "sp|Q16891|MIC60_HUMAN,sp|O00463|TRAF5_HUMAN,tr|B9A067|B9A067_HUMAN,tr|C9J406|C9J406_HUMAN,tr|H7C463|H7C463_HUMAN" 5 759.4127 1.03 41148 4330 2 759.411599 380.7136 MICOS complex subunit MIC60 OS=Homo sapiens OX=9606 GN=IMMT PE=1 SV=1 5.72 1484.7 - 2.44E+06 - - - -1.409 - 1.112 0.057 - 174.1 1 2 0 -0.0011 7 0 0 0 9.72E+08 9.40E+08 - - - -0.202 0.9666 221125_WJC_METTL3_EV_vs_WT_F04.04332.04332.2 1.83 12-Jul K.TLEEEAK.T sp|P35579|MYH9_HUMAN 1 818.4022 1.07 41150 4332 2 818.399986 410.2084 Myosin-9 OS=Homo sapiens OX=9606 GN=MYH9 PE=1 SV=4 4.25 1484.9 - 1.58E+06 - - - -2.6601 - 1.249 0.12 - 203.2 1 2 0 -0.0022 7 0 0 0 3.43E+08 3.22E+08 - - - 0.6311 0.9609 221125_WJC_METTL3_EV_vs_WT_F04.04345.04345.2 7.54 12-Jun K.LQTVAEK.E "sp|Q16531|DDB1_HUMAN,tr|A0A7P0TAK7|A0A7P0TAK7_HUMAN,tr|A0A7P0T870|A0A7P0T870_HUMAN,tr|A0A7P0TB30|A0A7P0TB30_HUMAN,tr|A0A7P0Z3Z5|A0A7P0Z3Z5_HUMAN,tr|F5GY55|F5GY55_HUMAN,tr|A0A7P0Z4B9|A0A7P0Z4B9_HUMAN,tr|A0A7P0T965|A0A7P0T965_HUMAN" 8 787.444 0.73 41156 4345 2 787.442326 394.7293 DNA damage-binding protein 1 OS=Homo sapiens OX=9606 GN=DDB1 PE=1 SV=1 6 1486.5 - 3.66E+06 - - - -2.0865 - 1.201 0.085 - 112.3 1 2 0 -0.0016 7 0 0 0 7.25E+07 9.94E+07 - - - 0.2486 0.9989 221125_WJC_METTL3_EV_vs_WT_F04.04347.04347.2 0.00629 14-Aug K.AVEC[160.03]PPPR.T sp|Q15046|SYK_HUMAN 1 924.4487 0.89 41158 4347 2 924.447048 463.2316 Lysine--tRNA ligase OS=Homo sapiens OX=9606 GN=KARS1 PE=1 SV=3 6.04 1486.8 - 584015 - - - -1.827 - 1.538 0.339 - 323.2 1 2 0 -0.0017 8 0 0 0 3.81E+07 4.26E+07 - - - 2.8426 0.9626 221125_WJC_METTL3_EV_vs_WT_F04.04350.04350.2 0.0704 14-Jun R.LAANPDPK[136.11].K "sp|Q14241|ELOA1_HUMAN,tr|A0A024RAC6|A0A024RAC6_HUMAN" 2 832.4534 2.09 41159 4350 2 832.450171 417.234 Elongin-A OS=Homo sapiens OX=9606 GN=ELOA PE=1 SV=2 5.84 1487.2 - 3.05E+06 - - - -3.9005 - 1.165 0.228 - 108.1 1 2 0 -0.0032 8 0 0 0 1.72E+08 8.23E+07 - - - 1.1846 0.999 221125_WJC_METTL3_EV_vs_WT_F04.04352.04352.2 0.045 14-Jul R.LVTEC[160.03]EQK[136.11].K sp|Q06546|GABPA_HUMAN 1 1013.4943 0.86 41161 4352 2 1013.493091 507.7544 GA-binding protein alpha chain OS=Homo sapiens OX=9606 GN=GABPA PE=1 SV=1 4.53 1487.3 - 345290 - - - -1.1899 - 1.306 0.377 - 150.9 1 2 0 -0.0012 8 0 0 0 4.97E+06 5.77E+06 - - - 2.6303 0.9791 221125_WJC_METTL3_EV_vs_WT_F04.04355.04355.2 0.967 12-Jul K.GLSEDTR[166.11].S "sp|Q8IWS0|PHF6_HUMAN,tr|Q5JRC6|Q5JRC6_HUMAN,tr|A0A0D9SGE8|A0A0D9SGE8_HUMAN" 3 786.3747 0.76 41162 4355 2 786.372882 394.1946 PHD finger protein 6 OS=Homo sapiens OX=9606 GN=PHF6 PE=1 SV=1 4.37 1487.7 - 6.72E+06 - - - -2.3335 - 1.166 0.172 - 197.9 1 2 0 -0.0018 7 0 0 0 2.84E+09 3.74E+09 - - - 0.7974 0.9826 221125_WJC_METTL3_EV_vs_WT_F04.04357.04357.2 0.304 16-Aug R.ALAENSGVK[136.11].A "sp|P50990|TCPQ_HUMAN,tr|H7C2U0|H7C2U0_HUMAN" 2 895.4854 0.41 41163 4357 2 895.484217 448.75 T-complex protein 1 subunit theta OS=Homo sapiens OX=9606 GN=CCT8 PE=1 SV=4 6.05 1487.9 - 814108 - - - -1.3724 - 1.675 0.012 - 199.2 2 2 0 -0.0012 9 0 0 0 1.73E+09 4.25E+09 - - - 0.4871 0.8403 221125_WJC_METTL3_EV_vs_WT_F04.04358.04358.2 0.418 16-Oct R.LQAAGNAVK[136.11].R "sp|Q9Y4G6|TLN2_HUMAN,sp|Q9Y490|TLN1_HUMAN,tr|A0A1B0GVU7|A0A1B0GVU7_HUMAN" 3 878.5065 2.13 41164 4358 2 878.501164 440.2605 Talin-2 OS=Homo sapiens OX=9606 GN=TLN2 PE=1 SV=4 8.75 1488 - 982445 - - - -6.0922 - 1.588 0.107 - 254.6 1 2 0 -0.0054 9 0 0 0 7.34E+07 3.45E+07 - - - 1.1676 0.9841 221125_WJC_METTL3_EV_vs_WT_F04.04361.04361.2 0.616 12-Jun K.GLSEDTR.S "sp|Q8IWS0|PHF6_HUMAN,tr|Q5JRC6|Q5JRC6_HUMAN,tr|A0A0D9SGE8|A0A0D9SGE8_HUMAN" 3 776.3664 0.54 41165 4361 2 776.364564 389.1905 PHD finger protein 6 OS=Homo sapiens OX=9606 GN=PHF6 PE=1 SV=1 4.37 1488.4 - 7.37E+06 - - - -2.4254 - 1.29 0.161 - 153.1 1 2 0 -0.0019 7 0 0 0 1.74E+08 3.23E+08 - - - 1.0364 0.9971 221125_WJC_METTL3_EV_vs_WT_F04.04362.04362.2 0.042 14-Aug R.IISANGC[160.03]K.V sp|P05023|AT1A1_HUMAN 1 861.4378 1.67 41166 4362 2 861.435823 431.7262 Sodium\potassium-transporting ATPase subunit alpha-1 OS=Homo sapiens OX=9606 GN=ATP1A1 PE=1 SV=1 8.22 1488.5 - 2.39E+06 - - - -2.3391 - 1.307 0.337 - 153.7 1 2 0 -0.002 8 0 0 0 1.66E+08 9.93E+07 - - - 2.3369 0.9885 221125_WJC_METTL3_EV_vs_WT_F04.04366.04366.2 0.17 12-Jul K.LGNPTDR[166.11].N "sp|O95292|VAPB_HUMAN,tr|E5RK64|E5RK64_HUMAN" 2 781.3958 2.11 41168 4366 2 781.39385 391.7052 Vesicle-associated membrane protein-associated protein B\C OS=Homo sapiens OX=9606 GN=VAPB PE=1 SV=3 5.84 1488.9 - 2.09E+06 - - - -2.4776 - 1.47 0.141 - 142.5 1 2 0 -0.0019 7 0 0 0 2.87E+08 1.36E+08 - - - 1.3025 0.9962 221125_WJC_METTL3_EV_vs_WT_F04.04374.04374.2 0.0958 12-Jun R.VGQTIER[166.11].M "sp|P52272|HNRPM_HUMAN,tr|M0R2I7|M0R2I7_HUMAN,tr|A0A087X0X3|A0A087X0X3_HUMAN,tr|M0QZM1|M0QZM1_HUMAN" 4 811.4427 1.57 41172 4374 2 811.440878 406.7286 Heterogeneous nuclear ribonucleoprotein M OS=Homo sapiens OX=9606 GN=HNRNPM PE=1 SV=3 5.97 1489.9 - 4.89E+06 - - - -2.291 - 1.466 0.245 - 123 1 2 0 -0.0019 7 0 0 0 6.56E+09 4.17E+09 - - - 2.0621 0.9959 221125_WJC_METTL3_EV_vs_WT_F04.04382.04382.2 0.00365 18-Oct R.AVGPTAEADK.S "sp|Q13123|RED_HUMAN,tr|D6REL4|D6REL4_HUMAN,tr|E7EQZ7|E7EQZ7_HUMAN" 3 957.4767 1.42 41174 4382 2 957.474584 479.7456 Protein Red OS=Homo sapiens OX=9606 GN=IK PE=1 SV=3 4.37 1491.1 - 582860 - - - -2.2361 - 1.699 0.197 - 307.1 1 2 0 -0.0021 10 0 0 0 9.95E+07 6.99E+07 - - - 1.9749 0.9985 221125_WJC_METTL3_EV_vs_WT_F04.04388.04388.2 0.00672 16-Aug R.ALAENSGVK.A "sp|P50990|TCPQ_HUMAN,tr|H7C2U0|H7C2U0_HUMAN" 2 887.4712 0.41 41176 4388 2 887.469079 444.7429 T-complex protein 1 subunit theta OS=Homo sapiens OX=9606 GN=CCT8 PE=1 SV=4 6.05 1491.8 - 6.00E+07 - - - -2.4418 - 1.601 0.349 - 165 1 2 0 -0.0022 9 0 0 0 1.73E+09 4.25E+09 - - - 2.9796 0.9495 221125_WJC_METTL3_EV_vs_WT_F04.04391.04391.2 0.949 12-Jun K.LETPPSK[136.11].L "sp|P35658|NU214_HUMAN,tr|A0A0A0MSW3|A0A0A0MSW3_HUMAN,tr|E9PKD2|E9PKD2_HUMAN,tr|B7ZAV2|B7ZAV2_HUMAN,tr|A0A494C1F2|A0A494C1F2_HUMAN,tr|H0Y837|H0Y837_HUMAN" 6 778.4316 2.32 41177 4391 2 778.429164 390.2231 Nuclear pore complex protein Nup214 OS=Homo sapiens OX=9606 GN=NUP214 PE=1 SV=2 6 1492.2 - 2.73E+06 - - - -3.1551 - 1.117 0.162 - 112.5 1 2 0 -0.0025 7 0 0 0 5.06E+08 2.18E+08 - - - 0.5874 0.9939 221125_WJC_METTL3_EV_vs_WT_F04.04393.04393.2 0.286 18-Sep R.AVGPTAEADK[136.11].S "sp|Q13123|RED_HUMAN,tr|D6REL4|D6REL4_HUMAN,tr|E7EQZ7|E7EQZ7_HUMAN" 3 965.4909 1.42 41179 4393 2 965.487917 483.7527 Protein Red OS=Homo sapiens OX=9606 GN=IK PE=1 SV=3 4.37 1492.4 - 1.45E+06 - - - -3.1155 - 1.675 0.229 - 168.1 1 2 0 -0.003 10 0 0 0 9.95E+07 6.99E+07 - - - 2.1712 0.997 221125_WJC_METTL3_EV_vs_WT_F04.04397.04397.2 0.0764 12-Jun K.VAQDLC[160.03]K[136.11].V "sp|P13804|ETFA_HUMAN,tr|H0YKF0|H0YKF0_HUMAN,tr|H0YLU7|H0YLU7_HUMAN" 3 840.4255 3.19 41181 4397 2 840.424336 421.22 "Electron transfer flavoprotein subunit alpha, mitochondrial OS=Homo sapiens OX=9606 GN=ETFA PE=1 SV=1" 5.8 1492.8 - 3.17E+06 - - - -1.3719 - 1.199 0.291 - 93.6 1 2 0 -0.0012 7 0 0 0 3.08E+08 9.65E+07 - - - 1.765 0.9985 221125_WJC_METTL3_EV_vs_WT_F04.04398.04398.2 0.0169 14-Aug K.AVEC[160.03]PPPR[166.11].T sp|Q15046|SYK_HUMAN 1 934.457 0.94 41182 4398 2 934.455019 468.2358 Lysine--tRNA ligase OS=Homo sapiens OX=9606 GN=KARS1 PE=1 SV=3 6.04 1493 - 733484 - - - -2.1274 - 1.821 0.266 - 337.8 1 2 0 -0.002 8 0 0 0 3.39E+07 3.60E+07 - - - 2.8128 0.9779 221125_WJC_METTL3_EV_vs_WT_F04.04403.04403.2 0.276 12-Aug R.LMVESHR.S "sp|P51570|GALK1_HUMAN,tr|K7EII7|K7EII7_HUMAN" 2 870.4382 1.36 41184 4403 2 870.441349 436.2264 Galactokinase OS=Homo sapiens OX=9606 GN=GALK1 PE=1 SV=1 6.75 1493.6 - 1.85E+06 - - - 3.6499 - 1.439 0.172 - 248.5 1 2 0 0.0032 7 0 0 0 3.81E+07 2.80E+07 - - - 1.4636 0.9936 221125_WJC_METTL3_EV_vs_WT_F04.04418.04418.2 0.00249 16-Aug K.AAFGGSGGR.G sp|P35908|K22E_HUMAN 1 778.3722 0.75 41188 4418 2 778.368219 390.1934 "Keratin, type II cytoskeletal 2 epidermal OS=Homo sapiens OX=9606 GN=KRT2 PE=1 SV=2" 9.79 1495.8 - 4.91E+06 - - - -5.1158 - 1.695 0.403 - 145.1 1 2 0 -0.004 9 0 0 0 2.87E+09 3.81E+09 - - - 3.5429 0.9895 221125_WJC_METTL3_EV_vs_WT_F04.04426.04426.2 0.00747 18-Oct K.IAEVGAGGNK[136.11].S "sp|Q00577|PURA_HUMAN,tr|A0A494C0H6|A0A494C0H6_HUMAN" 2 922.4963 0.76 41191 4426 2 922.491955 462.2554 Transcriptional activator protein Pur-alpha OS=Homo sapiens OX=9606 GN=PURA PE=1 SV=2 6 1496.8 - 457781 - - - -4.7588 - 1.699 0.303 - 261.2 1 2 0 -0.0044 10 0 0 0 1.31E+07 1.73E+07 - - - 2.7571 0.9966 221125_WJC_METTL3_EV_vs_WT_F04.04428.04428.2 0.000522 12-Aug R.C[160.03]DSADLR.H "sp|Q9NYF8|BCLF1_HUMAN,tr|E9PKI6|E9PKI6_HUMAN,tr|E9PK91|E9PK91_HUMAN,tr|E9PK09|E9PK09_HUMAN,tr|E9PQN2|E9PQN2_HUMAN" 5 835.3494 2.07 41192 4428 2 835.346899 418.682 Bcl-2-associated transcription factor 1 OS=Homo sapiens OX=9606 GN=BCLAF1 PE=1 SV=2 4.21 1497 - 1.32E+08 - - - -3.0143 - 1.628 0.275 - 302.1 1 2 0 -0.0025 7 0 0 0 6.36E+09 3.08E+09 - - - 2.6156 0.9975 221125_WJC_METTL3_EV_vs_WT_F04.04430.04430.2 0.177 14-Jul K.AVTEMNGR[166.11].L "sp|Q13310|PABP4_HUMAN,sp|Q9H361|PABP3_HUMAN,sp|Q4VXU2|PAP1L_HUMAN,sp|P11940|PABP1_HUMAN,tr|A0A7I2V5W9|A0A7I2V5W9_HUMAN,tr|H0YEU6|H0YEU6_HUMAN,tr|A0A7I2YQE4|A0A7I2YQE4_HUMAN,tr|A0A7I2V649|A0A7I2V649_HUMAN,tr|B1ANR0|B1ANR0_HUMAN,tr|A0A6Q8JFT6|A0A6Q8JFT6_HUMAN,tr|A0A7I2V4L7|A0A7I2V4L7_HUMAN,tr|H0YB86|H0YB86_HUMAN,tr|H0YAR2|H0YAR2_HUMAN,tr|E7ERJ7|E7ERJ7_HUMAN,tr|A0A7I2V598|A0A7I2V598_HUMAN,tr|A0A7I2YQ88|A0A7I2YQ88_HUMAN,tr|A0A7I2V4V6|A0A7I2V4V6_HUMAN,tr|H0Y5F5|H0Y5F5_HUMAN,tr|A0A6I8PS38|A0A6I8PS38_HUMAN,tr|A0A6I8PLA1|A0A6I8PLA1_HUMAN,tr|A0A087WTT1|A0A087WTT1_HUMAN,tr|A0A7I2YQ90|A0A7I2YQ90_HUMAN,tr|A0A7I2V4N4|A0A7I2V4N4_HUMAN,tr|E7EQV3|E7EQV3_HUMAN" 24 886.4206 1.32 41194 4430 2 886.418239 444.2176 Polyadenylate-binding protein 4 OS=Homo sapiens OX=9606 GN=PABPC4 PE=1 SV=1 6.05 1497.1 - 3.44E+06 - - - -2.6872 - 1.779 0.259 - 208.2 1 2 0 -0.0024 8 0 0 0 8.45E+08 6.39E+08 - - - 2.6906 0.9983 221125_WJC_METTL3_EV_vs_WT_F04.04439.04439.2 0.00153 14-Oct K.C[160.03]GGTLEER.A sp|Q12874|SF3A3_HUMAN 1 920.4022 3.9 41197 4439 2 920.399119 461.2084 Splicing factor 3A subunit 3 OS=Homo sapiens OX=9606 GN=SF3A3 PE=1 SV=1 4.53 1498.2 - 1.41E+06 - - - -3.3268 - 2.165 0.295 - 593.5 1 2 0 -0.0031 8 0 0 0 1.52E+08 3.90E+07 - - - 3.5485 0.9892 221125_WJC_METTL3_EV_vs_WT_F04.04446.04446.2 0.00372 14-Aug K.LSTAC[160.03]PGR[166.11].V sp|P55060|XPO2_HUMAN 1 870.4257 0.92 41199 4446 2 870.420471 436.2201 Exportin-2 OS=Homo sapiens OX=9606 GN=CSE1L PE=1 SV=3 8.25 1499.2 - 2.38E+06 - - - -6.0154 - 1.645 0.423 - 202.2 1 2 0 -0.0052 8 0 0 0 1.00E+08 1.09E+08 - - - 3.6648 0.9757 221125_WJC_METTL3_EV_vs_WT_F04.04448.04448.2 0.921 12-Jul R.VTQEEIK[136.11].K "sp|O00422|SAP18_HUMAN,tr|U3KQ12|U3KQ12_HUMAN" 2 853.4636 1.31 41200 4448 2 853.460341 427.7391 Histone deacetylase complex subunit SAP18 OS=Homo sapiens OX=9606 GN=SAP18 PE=1 SV=1 4.53 1499.4 - 1.01E+07 - - - -3.8748 - 1.475 0.166 - 155.4 1 2 0 -0.0033 7 0 0 0 1.02E+09 7.83E+08 - - - 1.4975 0.9974 221125_WJC_METTL3_EV_vs_WT_F04.04452.04452.2 0.000162 14-Jul K.AVTEMNGR.L "sp|Q13310|PABP4_HUMAN,sp|Q9H361|PABP3_HUMAN,sp|Q4VXU2|PAP1L_HUMAN,sp|P11940|PABP1_HUMAN,tr|A0A7I2V5W9|A0A7I2V5W9_HUMAN,tr|H0YEU6|H0YEU6_HUMAN,tr|A0A7I2YQE4|A0A7I2YQE4_HUMAN,tr|A0A7I2V649|A0A7I2V649_HUMAN,tr|B1ANR0|B1ANR0_HUMAN,tr|A0A6Q8JFT6|A0A6Q8JFT6_HUMAN,tr|A0A7I2V4L7|A0A7I2V4L7_HUMAN,tr|H0YB86|H0YB86_HUMAN,tr|H0YAR2|H0YAR2_HUMAN,tr|E7ERJ7|E7ERJ7_HUMAN,tr|A0A7I2V598|A0A7I2V598_HUMAN,tr|A0A7I2YQ88|A0A7I2YQ88_HUMAN,tr|A0A7I2V4V6|A0A7I2V4V6_HUMAN,tr|H0Y5F5|H0Y5F5_HUMAN,tr|A0A6I8PS38|A0A6I8PS38_HUMAN,tr|A0A6I8PLA1|A0A6I8PLA1_HUMAN,tr|A0A087WTT1|A0A087WTT1_HUMAN,tr|A0A7I2YQ90|A0A7I2YQ90_HUMAN,tr|A0A7I2V4N4|A0A7I2V4N4_HUMAN,tr|E7EQV3|E7EQV3_HUMAN" 24 876.4124 1.33 41202 4452 2 876.409526 439.2135 Polyadenylate-binding protein 4 OS=Homo sapiens OX=9606 GN=PABPC4 PE=1 SV=1 6.05 1499.8 - 4.18E+07 - - - -3.2234 - 1.526 0.367 - 166.2 1 2 0 -0.0028 8 0 0 0 8.48E+08 6.39E+08 - - - 3.0255 0.999 221125_WJC_METTL3_EV_vs_WT_F04.04453.04453.2 1.05E-05 14-Oct K.C[160.03]GGTLEER[166.11].A sp|Q12874|SF3A3_HUMAN 1 930.4105 4.02 41203 4453 2 930.407276 466.2125 Splicing factor 3A subunit 3 OS=Homo sapiens OX=9606 GN=SF3A3 PE=1 SV=1 4.53 1499.9 - 2.03E+06 - - - -3.4125 - 2.201 0.406 - 666.7 1 2 0 -0.0032 8 0 0 0 1.57E+08 3.90E+07 - - - 4.418 0.9936 221125_WJC_METTL3_EV_vs_WT_F04.04466.04466.2 0.398 12-Jun K.QVTEEVR.K sp|P12270|TPR_HUMAN 1 859.4399 1.51 41207 4466 2 859.438407 430.7272 Nucleoprotein TPR OS=Homo sapiens OX=9606 GN=TPR PE=1 SV=3 4.53 1501.7 - 2.16E+06 - - - -1.7907 - 1.494 0.144 - 173.4 1 2 0 -0.0015 7 0 0 0 5.30E+07 3.50E+07 - - - 1.3761 0.9901 221125_WJC_METTL3_EV_vs_WT_F04.04471.04471.2 0.119 12-Aug K.ADLEAQR.D "sp|P61106|RAB14_HUMAN,tr|X6RFL8|X6RFL8_HUMAN" 2 801.3981 0.54 41210 4471 2 801.395483 401.7063 Ras-related protein Rab-14 OS=Homo sapiens OX=9606 GN=RAB14 PE=1 SV=4 4.37 1502.3 - 5.64E+06 - - - -3.2418 - 1.771 0.135 - 242.2 1 2 0 -0.0026 7 0 0 0 1.90E+08 3.50E+08 - - - 1.8483 0.993 221125_WJC_METTL3_EV_vs_WT_F04.04473.04473.2 0.545 12-Jul R.HVVGEIR.R "sp|P51570|GALK1_HUMAN,tr|K7EII7|K7EII7_HUMAN" 2 808.4555 1.64 41211 4473 2 808.453613 405.235 Galactokinase OS=Homo sapiens OX=9606 GN=GALK1 PE=1 SV=1 6.75 1502.5 - 5.00E+06 - - - -2.3786 - 1.547 0.162 - 211.9 1 2 0 -0.0019 7 0 0 0 1.76E+08 1.07E+08 - - - 1.6194 0.9891 221125_WJC_METTL3_EV_vs_WT_F04.04477.04477.2 0.683 12-Jul R.VQEQELK[136.11].S "sp|Q16891|MIC60_HUMAN,tr|B9A067|B9A067_HUMAN,tr|C9J406|C9J406_HUMAN,tr|H7C463|H7C463_HUMAN" 4 880.4745 1.34 41213 4477 2 880.471229 441.2445 MICOS complex subunit MIC60 OS=Homo sapiens OX=9606 GN=IMMT PE=1 SV=1 4.53 1503 - 5.08E+06 - - - -3.7684 - 1.495 0.24 - 142.8 1 2 0 -0.0033 7 0 0 0 1.10E+09 8.17E+08 - - - 2.0868 0.936 221125_WJC_METTL3_EV_vs_WT_F04.04479.04479.2 1.35 16-Jun K.LVGGTTPGK[136.11].G "sp|P53597|SUCA_HUMAN,tr|A0A494C0D1|A0A494C0D1_HUMAN" 2 836.4847 1.62 41215 4479 2 836.482736 419.2496 "Succinate--CoA ligase [ADP\GDP-forming] subunit alpha, mitochondrial OS=Homo sapiens OX=9606 GN=SUCLG1 PE=1 SV=4" 8.75 1503.1 - 1.32E+07 - - - -2.3694 - 0.92 0.169 - 108.6 1 2 0 -0.002 9 0 0 0 3.79E+08 2.34E+08 - - - 0.0474 0.9591 221125_WJC_METTL3_EV_vs_WT_F04.04485.04485.2 0.0159 12-Jul K.LAESVEK[136.11].A sp|Q9Y5B9|SP16H_HUMAN 1 782.4265 0.67 41218 4485 2 782.424188 392.2205 FACT complex subunit SPT16 OS=Homo sapiens OX=9606 GN=SUPT16H PE=1 SV=1 4.53 1503.9 - 5.95E+06 - - - -2.9984 - 1.606 0.034 - 156.6 2 2 0 -0.0023 7 0 0 0 1.52E+08 2.27E+08 - - - 0.658 0.9911 221125_WJC_METTL3_EV_vs_WT_F04.04494.04494.2 0.0669 12-Jun K.FAETQPK[136.11].K sp|P26641|EF1G_HUMAN 1 827.4269 1.08 41225 4494 2 827.425037 414.7207 Elongation factor 1-gamma OS=Homo sapiens OX=9606 GN=EEF1G PE=1 SV=3 6 1504.7 - 1.37E+07 - - - -2.2141 - 1.123 0.263 - 98.1 1 2 0 -0.0018 7 0 0 0 2.51E+08 2.32E+08 - - - 1.3505 0.9637 221125_WJC_METTL3_EV_vs_WT_F04.04499.04499.2 0.586 12-May R.ILPK[136.11]PTR[166.11].K "sp|P62081|RS7_HUMAN,tr|B5MCP9|B5MCP9_HUMAN,tr|A0A2R8Y623|A0A2R8Y623_HUMAN" 3 841.5504 0.82 41228 4499 2 841.547908 421.7825 40S ribosomal protein S7 OS=Homo sapiens OX=9606 GN=RPS7 PE=1 SV=1 11 1505.2 - 9.57E+06 - - - -3.0123 - 0.973 0.243 - 118.9 1 2 0 -0.0025 7 0 0 0 2.96E+08 3.62E+08 - - - 0.7483 0.792 221125_WJC_METTL3_EV_vs_WT_F04.04506.04506.2 2.73 12-May R.ILPKPTR.K "sp|P62081|RS7_HUMAN,tr|B5MCP9|B5MCP9_HUMAN,tr|A0A2R8Y623|A0A2R8Y623_HUMAN" 3 823.528 0.82 41232 4506 2 823.525672 412.7713 40S ribosomal protein S7 OS=Homo sapiens OX=9606 GN=RPS7 PE=1 SV=1 11 1505.9 - 9.34E+06 - - - -2.7941 - 1 0.049 - 107.3 1 2 0 -0.0023 7 0 0 0 2.96E+08 3.62E+08 - - - -0.5978 0.9751 221125_WJC_METTL3_EV_vs_WT_F04.04508.04508.2 0.159 12-Apr R.LYQEC[160.03]EK[136.11].L "sp|Q92598|HS105_HUMAN,sp|O95757|HS74L_HUMAN,tr|D6RJ96|D6RJ96_HUMAN,tr|E9PDE8|E9PDE8_HUMAN,tr|A0A0A0MSM0|A0A0A0MSM0_HUMAN" 5 976.4415 0.12 41233 4508 2 976.439484 489.228 Heat shock protein 105 kDa OS=Homo sapiens OX=9606 GN=HSPH1 PE=1 SV=1 4.53 1506.2 - 3.83E+06 - - - -2.0984 - 1.065 0.23 - 36.9 7 2 0 -0.002 7 0 0 0 9.90E+06 8.54E+07 - - - 0.5612 0.9617 221125_WJC_METTL3_EV_vs_WT_F04.04519.04519.2 1.86 12-Jun K.EVATDVR[166.11].L "sp|O75534|CSDE1_HUMAN,tr|E9PLT0|E9PLT0_HUMAN,tr|E9PNG3|E9PNG3_HUMAN" 3 798.4111 1.89 41239 4519 2 798.408679 400.2128 Cold shock domain-containing protein E1 OS=Homo sapiens OX=9606 GN=CSDE1 PE=1 SV=2 4.37 1507.4 - 4.51E+06 - - - -3.0348 - 1.224 0.141 - 207.4 1 2 0 -0.0024 7 0 0 0 5.02E+09 2.66E+09 - - - 0.7221 0.8024 221125_WJC_METTL3_EV_vs_WT_F04.04523.04523.2 3.1 14-Jul K.ILADQQDK.Y "sp|Q9Y265|RUVB1_HUMAN,tr|H7C4G5|H7C4G5_HUMAN" 2 929.4818 0.77 41240 4523 2 929.478781 465.7482 RuvB-like 1 OS=Homo sapiens OX=9606 GN=RUVBL1 PE=1 SV=1 4.21 1507.9 - 4.53E+06 - - - -3.2599 - 1.162 0.04 - 83 2 2 0 -0.003 8 0 0 0 1.14E+08 1.48E+08 - - - -0.3462 0.9654 221125_WJC_METTL3_EV_vs_WT_F04.04532.04532.2 2.65 12-Aug K.YLREEVK.T "sp|Q92615|LAR4B_HUMAN,sp|Q71RC2|LARP4_HUMAN,tr|Q96J85|Q96J85_HUMAN,tr|X6RLN4|X6RLN4_HUMAN" 4 935.5076 1.3 41245 4532 2 935.505368 468.7611 La-related protein 4B OS=Homo sapiens OX=9606 GN=LARP4B PE=1 SV=3 6.14 1508.9 - 9.13E+06 - - - -2.4201 - 1.666 0.221 - 235.2 1 2 1 -0.0023 7 0 0 0 1.82E+08 1.40E+08 - - - 2.2899 0.8472 221125_WJC_METTL3_EV_vs_WT_F04.04534.04534.2 1.12 14-Jun R.FTQSGTMK[136.11].L "sp|Q8NI51|CTCFL_HUMAN,sp|P49711|CTCF_HUMAN,tr|V9GY73|V9GY73_HUMAN,tr|A0A2R8YFL0|A0A2R8YFL0_HUMAN,tr|F5H2V8|F5H2V8_HUMAN,tr|A0A2R8Y595|A0A2R8Y595_HUMAN" 6 906.4361 0.92 41246 4534 2 906.430693 454.2253 Transcriptional repressor CTCFL OS=Homo sapiens OX=9606 GN=CTCFL PE=1 SV=2 8.75 1509.1 - 2.93E+06 - - - -5.9133 - 1.067 0.273 - 64 2 2 0 -0.0054 8 0 0 0 1.23E+07 1.34E+07 - - - 1.1168 0.9446 221125_WJC_METTL3_EV_vs_WT_F04.04538.04538.2 2.55 12-May R.VGSEIER.M "sp|P52272|HNRPM_HUMAN,tr|A0A087X0X3|A0A087X0X3_HUMAN,tr|M0QZM1|M0QZM1_HUMAN" 3 788.4028 1.89 41248 4538 2 788.401226 395.2087 Heterogeneous nuclear ribonucleoprotein M OS=Homo sapiens OX=9606 GN=HNRNPM PE=1 SV=3 4.53 1509.6 - 1.17E+07 - - - -2.037 - 1.105 0.115 - 73.8 3 2 0 -0.0016 7 0 0 0 5.03E+09 2.66E+09 - - - -0.0069 0.9789 221125_WJC_METTL3_EV_vs_WT_F04.04539.04539.2 0.48 12-Jun R.LLAQQQR.A "sp|Q8NDV7|TNR6A_HUMAN,tr|H3BTQ1|H3BTQ1_HUMAN,tr|H7C269|H7C269_HUMAN" 3 855.4927 1.92 41249 4539 2 855.490255 428.7536 Trinucleotide repeat-containing gene 6A protein OS=Homo sapiens OX=9606 GN=TNRC6A PE=1 SV=2 9.75 1509.6 - 3.19E+06 - - - -2.7996 - 1.217 0.185 - 112.6 1 2 0 -0.0024 7 0 0 0 5.35E+07 2.79E+07 - - - 1.0289 0.9988 221125_WJC_METTL3_EV_vs_WT_F04.04540.04540.2 0.0138 16-Sep K.VASQGEVVR.K "sp|P07814|SYEP_HUMAN,tr|V9GYZ6|V9GYZ6_HUMAN" 2 943.5087 0.94 41250 4540 2 943.507068 472.7616 Bifunctional glutamate\proline--tRNA ligase OS=Homo sapiens OX=9606 GN=EPRS1 PE=1 SV=5 5.97 1509.7 - 2.22E+06 - - - -1.7234 - 1.76 0.276 - 325 1 2 0 -0.0016 9 0 0 0 2.75E+08 2.94E+08 - - - 2.7145 0.9929 221125_WJC_METTL3_EV_vs_WT_F04.04549.04549.2 0.345 16-Jun R.IVSQPQPAR.R "sp|Q8IX12|CCAR1_HUMAN,tr|F5H2E6|F5H2E6_HUMAN,tr|F5H1H2|F5H1H2_HUMAN,tr|A0A0C4DGG8|A0A0C4DGG8_HUMAN,tr|F5H3E1|F5H3E1_HUMAN" 5 994.556 5.54 41254 4549 2 994.554404 498.2853 Cell division cycle and apoptosis regulator protein 1 OS=Homo sapiens OX=9606 GN=CCAR1 PE=1 SV=2 9.75 1510.8 - 2.59E+06 - - - -1.5836 - 1.26 0.22 - 92.1 2 2 0 -0.0016 9 0 0 0 7.16E+07 1.29E+07 - - - 1.1996 0.8204 221125_WJC_METTL3_EV_vs_WT_F04.04550.04550.2 4.4 16-Jul K.ALSGSSGYK[136.11].F "sp|P29084|T2EB_HUMAN,tr|E5RIW4|E5RIW4_HUMAN,tr|E5RH41|E5RH41_HUMAN" 3 876.4432 10.44 41255 4550 2 876.440483 439.2289 Transcription initiation factor IIE subunit beta OS=Homo sapiens OX=9606 GN=GTF2E2 PE=1 SV=1 8.63 1510.9 - 1.44E+06 - - - -3.1537 - 1.106 0.047 - 96.9 1 2 0 -0.0028 9 0 0 0 3.42E+08 3.28E+07 - - - -0.3213 0.961 221125_WJC_METTL3_EV_vs_WT_F04.04554.04554.2 0.31 12-Jul K.EFSSEAR.V "sp|Q12931|TRAP1_HUMAN,tr|I3L0K7|I3L0K7_HUMAN,tr|I3L239|I3L239_HUMAN,tr|I3L2D5|I3L2D5_HUMAN" 4 824.3664 2.08 41257 4554 2 824.362956 413.1905 "Heat shock protein 75 kDa, mitochondrial OS=Homo sapiens OX=9606 GN=TRAP1 PE=1 SV=3" 4.53 1511.3 - 3.61E+06 - - - -4.2348 - 1.245 0.216 - 287.2 1 2 0 -0.0035 7 0 0 0 1.48E+08 7.12E+07 - - - 1.3296 0.9954 221125_WJC_METTL3_EV_vs_WT_F04.04561.04561.2 0.0272 12-Jun R.VSMEEQR.Q "sp|P55036|PSMD4_HUMAN,tr|H0Y3Y9|H0Y3Y9_HUMAN,tr|Q5VWC4|Q5VWC4_HUMAN" 3 877.3964 1.02 41261 4561 2 877.393193 439.7055 26S proteasome non-ATPase regulatory subunit 4 OS=Homo sapiens OX=9606 GN=PSMD4 PE=1 SV=1 4.53 1512.1 - 3.60E+06 - - - -3.6175 - 1.443 0.346 - 136.4 1 2 0 -0.0032 7 0 0 0 1.90E+08 1.86E+08 - - - 2.7575 0.9532 221125_WJC_METTL3_EV_vs_WT_F04.04563.04563.2 8.51 14-Jun K.EIGGDVQK.H "sp|Q01518|CAP1_HUMAN,tr|Q5T0R6|Q5T0R6_HUMAN,tr|Q5T0R3|Q5T0R3_HUMAN,tr|Q5T0R4|Q5T0R4_HUMAN,tr|Q5T0R2|Q5T0R2_HUMAN,tr|Q5T0R1|Q5T0R1_HUMAN,tr|Q5T0R7|Q5T0R7_HUMAN,tr|Q5T0R5|Q5T0R5_HUMAN,tr|Q5T0R9|Q5T0R9_HUMAN" 9 844.429 4.02 41263 4563 2 844.428276 423.2218 Adenylyl cyclase-associated protein 1 OS=Homo sapiens OX=9606 GN=CAP1 PE=1 SV=5 4.37 1512.2 - 2.07E+06 - - - -0.913 - 1.244 0.06 - 97.9 10 2 0 -0.0008 8 0 0 0 1.55E+08 3.87E+07 - - - -0.3043 0.9435 221125_WJC_METTL3_EV_vs_WT_F04.04570.04570.2 0.453 14-Jun K.ETADAITK[136.11].E "sp|Q00765|REEP5_HUMAN,tr|E2QRG8|E2QRG8_HUMAN" 2 855.4429 1.04 41266 4570 2 855.439819 428.7287 Receptor expression-enhancing protein 5 OS=Homo sapiens OX=9606 GN=REEP5 PE=1 SV=3 4.37 1513 - 3.81E+06 - - - -3.6168 - 1.317 0.117 - 184.8 1 2 0 -0.0031 8 0 0 0 8.39E+07 8.04E+07 - - - 0.7347 0.9971 221125_WJC_METTL3_EV_vs_WT_F04.04580.04580.2 0.0514 16-Sep R.LAEAEETAR.T "sp|Q8N163|CCAR2_HUMAN,tr|H0YB24|H0YB24_HUMAN,tr|G3V119|G3V119_HUMAN" 3 988.4825 1.53 41271 4580 2 988.47899 495.2485 Cell cycle and apoptosis regulator protein 2 OS=Homo sapiens OX=9606 GN=CCAR2 PE=1 SV=2 4.25 1514.1 - 5.35E+06 - - - -3.5904 - 1.92 0.31 - 273 1 2 0 -0.0035 9 0 0 0 9.99E+07 6.52E+07 - - - 3.2168 0.9972 221125_WJC_METTL3_EV_vs_WT_F04.04587.04587.2 0.019 14-Jul R.VSTEVDAR.L "sp|P37837|TALDO_HUMAN,tr|F2Z393|F2Z393_HUMAN" 2 875.4349 3.51 41274 4587 2 875.431263 438.7247 Transaldolase OS=Homo sapiens OX=9606 GN=TALDO1 PE=1 SV=2 4.37 1514.9 - 3.75E+06 - - - -4.11 - 1.729 0.402 - 175.2 1 2 0 -0.0036 8 0 0 0 6.09E+07 1.74E+07 - - - 3.6604 0.9988 221125_WJC_METTL3_EV_vs_WT_F04.04621.04621.2 0.00731 16-Sep K.LQANGPVAK[136.11].K "sp|Q14978|NOLC1_HUMAN,tr|S4R3C2|S4R3C2_HUMAN,tr|A0A0A0MRM9|A0A0A0MRM9_HUMAN" 3 904.5222 1.79 41286 4621 2 904.5197 453.2684 Nucleolar and coiled-body phosphoprotein 1 OS=Homo sapiens OX=9606 GN=NOLC1 PE=1 SV=2 8.75 1519.3 - 3.50E+06 - - - -2.7263 - 1.936 0.346 - 210.2 1 2 0 -0.0025 9 0 0 0 5.82E+08 3.25E+08 - - - 3.507 0.9157 221125_WJC_METTL3_EV_vs_WT_F04.04629.04629.2 0.153 16-Aug K.LQANGPVAK.K "sp|Q14978|NOLC1_HUMAN,tr|S4R3C2|S4R3C2_HUMAN,tr|A0A0A0MRM9|A0A0A0MRM9_HUMAN" 3 896.508 1.8 41289 4629 2 896.502269 449.2613 Nucleolar and coiled-body phosphoprotein 1 OS=Homo sapiens OX=9606 GN=NOLC1 PE=1 SV=2 8.75 1520.3 - 1.31E+07 - - - -6.3547 - 1.575 0.203 - 158.1 1 2 0 -0.0057 9 0 0 0 5.82E+08 3.23E+08 - - - 1.8528 0.9291 221125_WJC_METTL3_EV_vs_WT_F04.04649.04649.2 0.621 12-Aug R.ELEAEER[166.11].E sp|Q8TAE8|G45IP_HUMAN 1 884.4115 1.96 41298 4649 2 884.40865 443.213 Growth arrest and DNA damage-inducible proteins-interacting protein 1 OS=Homo sapiens OX=9606 GN=GADD45GIP1 PE=1 SV=1 4.09 1522.7 - 4.95E+06 - - - -3.218 - 1.429 0.028 - 356.1 1 2 0 -0.0028 7 0 0 0 1.51E+08 7.72E+07 - - - 0.378 0.9981 221125_WJC_METTL3_EV_vs_WT_F04.04656.04656.2 0.000393 16-Nov R.TPVMNSEAK.V sp|Q15061|WDR43_HUMAN 1 975.4695 1.85 41303 4656 2 975.465318 488.742 WD repeat-containing protein 43 OS=Homo sapiens OX=9606 GN=WDR43 PE=1 SV=3 5.66 1523.6 - 1.97E+06 - - - -4.32 - 2.147 0.427 - 564.8 1 2 0 -0.0042 9 0 0 0 5.40E+07 2.93E+07 - - - 4.404 0.9276 221125_WJC_METTL3_EV_vs_WT_F04.04659.04659.2 0.625 12-Jul R.ELEAEER.E sp|Q8TAE8|G45IP_HUMAN 1 874.4032 1.9 41305 4659 2 874.400772 438.2089 Growth arrest and DNA damage-inducible proteins-interacting protein 1 OS=Homo sapiens OX=9606 GN=GADD45GIP1 PE=1 SV=1 4.09 1523.9 - 9.24E+06 - - - -2.8065 - 1.285 0.045 - 295.6 1 2 0 -0.0025 7 0 0 0 1.54E+08 8.07E+07 - - - 0.1671 0.9759 221125_WJC_METTL3_EV_vs_WT_F04.04661.04661.2 2.69 12-Jul R.SGEPLDR.A "sp|Q969Y2|GTPB3_HUMAN,tr|M0R0S9|M0R0S9_HUMAN,tr|M0R1X0|M0R1X0_HUMAN" 3 772.3715 242.88 41306 4661 2 772.369964 387.193 "tRNA modification GTPase GTPBP3, mitochondrial OS=Homo sapiens OX=9606 GN=GTPBP3 PE=1 SV=2" 4.37 1524.1 - 4.04E+06 - - - -2.0301 - 1.261 0.105 - 160.4 1 2 0 -0.0016 7 0 0 0 1.31E+10 5.41E+07 - - - 0.5508 0.9953 221125_WJC_METTL3_EV_vs_WT_F04.04662.04662.2 0.375 12-Jun K.FGNPGER[166.11].L "sp|Q92841|DDX17_HUMAN,tr|A0A5H1ZRQ2|A0A5H1ZRQ2_HUMAN,tr|A0A1X7SBZ2|A0A1X7SBZ2_HUMAN" 3 785.3696 0.46 41307 4662 2 785.36898 393.6921 Probable ATP-dependent RNA helicase DDX17 OS=Homo sapiens OX=9606 GN=DDX17 PE=1 SV=2 6 1524.2 - 1.33E+06 - - - -0.7538 - 1.366 0.178 - 113.3 2 2 0 -0.0006 7 0 0 0 1.86E+08 4.02E+08 - - - 1.2093 1 221125_WJC_METTL3_EV_vs_WT_F04.04667.04667.2 0.000113 16-Nov R.TPVMNSEAK[136.11].V sp|Q15061|WDR43_HUMAN 1 983.4837 1.7 41309 4667 2 983.480914 492.7491 WD repeat-containing protein 43 OS=Homo sapiens OX=9606 GN=WDR43 PE=1 SV=3 5.66 1524.8 - 1.88E+06 - - - -2.8653 - 2.531 0.559 - 579.5 1 2 0 -0.0028 9 0 0 0 4.64E+07 2.73E+07 - - - 5.8554 0.9966 221125_WJC_METTL3_EV_vs_WT_F04.04669.04669.2 0.142 12-Jul K.NVPTNVR.S "sp|Q8IWZ3|ANKH1_HUMAN,tr|A0A0A0MQZ8|A0A0A0MQZ8_HUMAN,tr|H0Y472|H0Y472_HUMAN,tr|H0Y7Y3|H0Y7Y3_HUMAN,tr|H0Y4P6|H0Y4P6_HUMAN,tr|H0Y785|H0Y785_HUMAN" 6 798.4348 1.42 41311 4669 2 798.43369 400.2247 Ankyrin repeat and KH domain-containing protein 1 OS=Homo sapiens OX=9606 GN=ANKHD1 PE=1 SV=1 9.75 1525 - 3.37E+06 - - - -1.3915 - 1.223 0.269 - 181.8 1 2 0 -0.0011 7 0 0 0 3.79E+08 2.67E+08 - - - 1.6653 0.9916 221125_WJC_METTL3_EV_vs_WT_F04.04674.04674.2 0.454 14-Jul K.AHLGTALK[136.11].A "sp|P62266|RS23_HUMAN,tr|D6RDJ2|D6RDJ2_HUMAN,tr|D6R9I7|D6R9I7_HUMAN,tr|D6RD47|D6RD47_HUMAN,tr|D6RIX0|D6RIX0_HUMAN" 5 817.4901 0.88 41314 4674 2 817.488695 409.7523 40S ribosomal protein S23 OS=Homo sapiens OX=9606 GN=RPS23 PE=1 SV=3 8.8 1525.6 - 5.05E+06 - - - -1.7652 - 1.664 0.08 - 194.8 1 2 0 -0.0014 8 0 0 0 1.38E+08 1.57E+08 - - - 1.1672 0.9937 221125_WJC_METTL3_EV_vs_WT_F04.04680.04680.2 0.326 14-Jul R.QMSGAQIK[136.11].L "sp|P57721|PCBP3_HUMAN,sp|Q15366|PCBP2_HUMAN,sp|Q15365|PCBP1_HUMAN,tr|E9PFP8|E9PFP8_HUMAN,tr|F8VRH0|F8VRH0_HUMAN,tr|J3QT27|J3QT27_HUMAN,tr|F8VZX2|F8VZX2_HUMAN,tr|H3BRU6|H3BRU6_HUMAN,tr|H3BSS4|H3BSS4_HUMAN" 9 869.452 0.9 41317 4680 2 869.450487 435.7333 Poly(rC)-binding protein 3 OS=Homo sapiens OX=9606 GN=PCBP3 PE=1 SV=2 8.75 1526.4 - 1.07E+07 - - - -1.7827 - 1.136 0.265 - 156.4 1 2 0 -0.0015 8 0 0 0 2.93E+08 3.24E+08 - - - 1.3824 0.9642 221125_WJC_METTL3_EV_vs_WT_F04.04682.04682.2 5.43 12-Jun K.LIEESQR.K sp|Q9H307|PININ_HUMAN 1 873.4556 2.84 41319 4682 2 873.454534 437.7351 Pinin OS=Homo sapiens OX=9606 GN=PNN PE=1 SV=5 4.53 1526.5 - 1.07E+07 - - - -1.2159 - 1.142 0.067 - 121.7 1 2 0 -0.0011 7 0 0 0 4.20E+08 1.48E+08 - - - -0.0437 0.9986 221125_WJC_METTL3_EV_vs_WT_F04.04683.04683.2 0.392 16-Oct K.IQNGAQGIR[166.11].F "sp|P31943|HNRH1_HUMAN,tr|E7EQJ0|E7EQJ0_HUMAN,tr|D6RIH9|D6RIH9_HUMAN,tr|D6RJ04|D6RJ04_HUMAN,tr|D6RFM3|D6RFM3_HUMAN,tr|E9PCY7|E9PCY7_HUMAN,tr|D6RIT2|D6RIT2_HUMAN,tr|D6R9T0|D6R9T0_HUMAN,tr|D6RIU0|D6RIU0_HUMAN,tr|D6RAM1|D6RAM1_HUMAN,tr|D6RBM0|D6RBM0_HUMAN,tr|G8JLB6|G8JLB6_HUMAN,tr|D6RF17|D6RF17_HUMAN,tr|D6RDL0|D6RDL0_HUMAN,tr|D6RDU3|D6RDU3_HUMAN,tr|E7EN40|E7EN40_HUMAN" 16 965.5282 1.14 41320 4683 2 965.526007 483.7714 Heterogeneous nuclear ribonucleoprotein H OS=Homo sapiens OX=9606 GN=HNRNPH1 PE=1 SV=4 9.75 1526.7 - 1.27E+06 - - - -2.2692 - 2.086 0.238 - 277.4 1 2 0 -0.0022 9 0 0 0 5.65E+08 4.97E+08 - - - 2.9253 0.9995 221125_WJC_METTL3_EV_vs_WT_F04.04684.04684.2 0.000132 16-Sep K.IQNGAQGIR.F "sp|P31943|HNRH1_HUMAN,tr|E7EQJ0|E7EQJ0_HUMAN,tr|D6RIH9|D6RIH9_HUMAN,tr|D6RJ04|D6RJ04_HUMAN,tr|D6RFM3|D6RFM3_HUMAN,tr|E9PCY7|E9PCY7_HUMAN,tr|D6RIT2|D6RIT2_HUMAN,tr|D6R9T0|D6R9T0_HUMAN,tr|D6RIU0|D6RIU0_HUMAN,tr|D6RAM1|D6RAM1_HUMAN,tr|D6RBM0|D6RBM0_HUMAN,tr|G8JLB6|G8JLB6_HUMAN,tr|D6RF17|D6RF17_HUMAN,tr|D6RDL0|D6RDL0_HUMAN,tr|D6RDU3|D6RDU3_HUMAN,tr|E7EN40|E7EN40_HUMAN" 16 955.5199 1.14 41321 4684 2 955.518834 478.7672 Heterogeneous nuclear ribonucleoprotein H OS=Homo sapiens OX=9606 GN=HNRNPH1 PE=1 SV=4 9.75 1526.8 - 852637 - - - -1.1449 - 1.902 0.31 - 212 1 2 0 -0.0011 9 0 0 0 5.65E+08 4.97E+08 - - - 3.1903 0.9975 221125_WJC_METTL3_EV_vs_WT_F04.04687.04687.2 0.0549 16-Jul R.LGQEATVGK[136.11].A "sp|P53396|ACLY_HUMAN,tr|K7ESG8|K7ESG8_HUMAN" 2 909.5011 0.68 41322 4687 2 909.498431 455.7578 ATP-citrate synthase OS=Homo sapiens OX=9606 GN=ACLY PE=1 SV=3 6 1527.2 - 5.73E+06 - - - -2.9302 - 1.418 0.379 - 130.6 1 2 0 -0.0027 9 0 0 0 6.39E+07 9.39E+07 - - - 2.8498 0.997 221125_WJC_METTL3_EV_vs_WT_F04.04692.04692.2 0.0298 14-Jul R.GFSANSAR.L "sp|P48668|K2C6C_HUMAN,sp|P04259|K2C6B_HUMAN,sp|P02538|K2C6A_HUMAN" 3 808.3828 20.13 41324 4692 2 808.380308 405.1987 "Keratin, type II cytoskeletal 6C OS=Homo sapiens OX=9606 GN=KRT6C PE=1 SV=3" 9.75 1527.8 - 2.63E+07 - - - -3.0394 - 1.41 0.362 - 158.2 1 2 0 -0.0025 8 0 0 0 4.62E+08 2.30E+07 - - - 2.7502 0.9933 221125_WJC_METTL3_EV_vs_WT_F04.04694.04694.2 0.0559 14-Aug R.QLAAEEER.R sp|Q15149|PLEC_HUMAN 1 944.4563 1.64 41326 4694 2 944.454463 473.2354 Plectin OS=Homo sapiens OX=9606 GN=PLEC PE=1 SV=3 4.25 1527.9 - 905904 - - - -1.9704 - 1.617 0.128 - 304.2 1 2 0 -0.0019 8 0 0 0 4.15E+07 2.53E+07 - - - 1.4352 0.9992 221125_WJC_METTL3_EV_vs_WT_F04.04695.04695.2 0.0936 14-Sep R.EATEQEIR.S "sp|Q9BWF3|RBM4_HUMAN,sp|Q9BQ04|RBM4B_HUMAN,tr|E9PM61|E9PM61_HUMAN,tr|D6R9K7|D6R9K7_HUMAN,tr|J3QRR5|J3QRR5_HUMAN,tr|E9PB51|E9PB51_HUMAN,tr|U3KQD5|U3KQD5_HUMAN,tr|E9PLB0|E9PLB0_HUMAN" 8 974.4669 1.53 41327 4695 2 974.467317 488.2407 RNA-binding protein 4 OS=Homo sapiens OX=9606 GN=RBM4 PE=1 SV=1 4.25 1528.1 - 877041 - - - 0.4392 - 1.66 0.274 - 482.6 1 2 0 0.0004 8 0 0 0 6.16E+07 4.03E+07 - - - 2.5932 0.9165 221125_WJC_METTL3_EV_vs_WT_F04.04699.04699.2 0.522 12-May R.LSQQLDK.V sp|P13984|T2FB_HUMAN 1 830.4498 1.66 41329 4699 2 830.447382 416.2322 General transcription factor IIF subunit 2 OS=Homo sapiens OX=9606 GN=GTF2F2 PE=1 SV=2 5.84 1528.5 - 6.29E+06 - - - -2.89 - 1.423 0.051 - 63.5 9 2 0 -0.0024 7 0 0 0 2.27E+08 1.37E+08 - - - 0.1084 0.9939 221125_WJC_METTL3_EV_vs_WT_F04.04700.04700.2 0.00527 14-Aug R.VFTTNNGR[166.11].H "sp|O00422|SAP18_HUMAN,tr|U3KQ12|U3KQ12_HUMAN,tr|U3KPY7|U3KPY7_HUMAN,tr|H7BZW6|H7BZW6_HUMAN" 4 917.4594 1.38 41330 4700 2 917.45724 459.737 Histone deacetylase complex subunit SAP18 OS=Homo sapiens OX=9606 GN=SAP18 PE=1 SV=1 9.72 1528.5 - 4.27E+06 - - - -2.4077 - 1.554 0.187 - 254.4 1 2 0 -0.0022 8 0 0 0 6.33E+08 4.61E+08 - - - 1.751 0.9847 221125_WJC_METTL3_EV_vs_WT_F04.04703.04703.2 3.73E-06 16-Oct R.PSQVVAETR[166.11].K sp|P13639|EF2_HUMAN 1 995.5275 0.54 41333 4703 2 995.52563 498.771 Elongation factor 2 OS=Homo sapiens OX=9606 GN=EEF2 PE=1 SV=4 6.43 1528.8 - 1.42E+06 - - - -1.9075 - 2.272 0.453 - 430.5 1 1 0 -0.0019 9 0 0 0 2.52E+07 4.63E+07 - - - 4.7605 0.7857 221125_WJC_METTL3_EV_vs_WT_F04.04706.04706.2 5.37 12-Jun K.QEGVEVR.V "sp|Q8NBZ7|UXS1_HUMAN,tr|C9JCB7|C9JCB7_HUMAN,tr|C9JFU6|C9JFU6_HUMAN,tr|C9JE50|C9JE50_HUMAN" 4 815.4137 1.28 41334 4706 2 815.409966 408.7141 UDP-glucuronic acid decarboxylase 1 OS=Homo sapiens OX=9606 GN=UXS1 PE=1 SV=1 4.53 1529.1 - 3.18E+06 - - - -4.6173 - 1.167 0.093 - 157.8 1 2 0 -0.0038 7 0 0 0 6.86E+07 5.38E+07 - - - 0.2161 0.908 221125_WJC_METTL3_EV_vs_WT_F04.04707.04707.2 0.458 12-Jun R.LDPNVQK[136.11].W "sp|Q6P1J9|CDC73_HUMAN,tr|A0A1B0GUB2|A0A1B0GUB2_HUMAN" 2 820.4534 1.53 41335 4707 2 820.450733 411.234 Parafibromin OS=Homo sapiens OX=9606 GN=CDC73 PE=1 SV=1 5.84 1529.2 - 2.04E+06 - - - -3.2726 - 1.322 0.04 - 132.2 1 2 0 -0.0027 7 0 0 0 8.17E+07 5.34E+07 - - - 0.2201 0.9541 221125_WJC_METTL3_EV_vs_WT_F04.04712.04712.2 5.22E-05 16-Nov R.PSQVVAETR.K sp|P13639|EF2_HUMAN 1 985.5193 0.54 41338 4712 2 985.516202 493.7669 Elongation factor 2 OS=Homo sapiens OX=9606 GN=EEF2 PE=1 SV=4 6.43 1529.8 - 1.93E+06 - - - -3.1019 - 2.214 0.407 - 487.8 1 1 0 -0.0031 9 0 0 0 2.52E+07 4.63E+07 - - - 4.3455 0.9993 221125_WJC_METTL3_EV_vs_WT_F04.04720.04720.2 0.00188 18-Oct R.GGAGVGSMTK[136.11].L sp|P39019|RS19_HUMAN 1 871.4313 1.15 41342 4720 2 871.428549 436.7229 40S ribosomal protein S19 OS=Homo sapiens OX=9606 GN=RPS19 PE=1 SV=2 8.75 1530.9 - 3.32E+07 - - - -3.1592 - 2.11 0.484 - 525.1 1 2 0 -0.0028 10 0 0 0 6.71E+08 5.83E+08 - - - 4.6992 0.9854 221125_WJC_METTL3_EV_vs_WT_F04.04721.04721.2 0.254 14-Aug K.SVLADQGK.S "sp|Q9NYF8|BCLF1_HUMAN,tr|E9PKI6|E9PKI6_HUMAN,tr|A0A1W2PQ43|A0A1W2PQ43_HUMAN,tr|E9PK91|E9PK91_HUMAN,tr|E9PK09|E9PK09_HUMAN,tr|E9PQN2|E9PQN2_HUMAN" 6 816.4341 2.05 41343 4721 2 816.435188 409.2243 Bcl-2-associated transcription factor 1 OS=Homo sapiens OX=9606 GN=BCLAF1 PE=1 SV=2 5.55 1530.9 - 5.89E+06 - - - 1.2934 - 1.315 0.106 - 197.7 1 2 0 0.0011 8 0 0 0 1.65E+10 8.04E+09 - - - 0.6495 0.9856 221125_WJC_METTL3_EV_vs_WT_F04.04722.04722.2 0.327 14-Sep K.SVLADQGK[136.11].S "sp|Q9NYF8|BCLF1_HUMAN,tr|E9PKI6|E9PKI6_HUMAN,tr|A0A1W2PQ43|A0A1W2PQ43_HUMAN,tr|E9PK91|E9PK91_HUMAN,tr|E9PK09|E9PK09_HUMAN,tr|E9PQN2|E9PQN2_HUMAN" 6 824.4483 2.05 41344 4722 2 824.444777 413.2314 Bcl-2-associated transcription factor 1 OS=Homo sapiens OX=9606 GN=BCLAF1 PE=1 SV=2 5.55 1531 - 4.92E+06 - - - -4.312 - 1.417 0.283 - 241.5 1 2 0 -0.0036 8 0 0 0 1.65E+10 8.04E+09 - - - 2.1813 0.9997 221125_WJC_METTL3_EV_vs_WT_F04.04729.04729.2 0.000401 20-Oct K.LVTAAGDQTAK[136.11].F "sp|Q9NZJ0|DTL_HUMAN,tr|F5GZ90|F5GZ90_HUMAN" 2 1081.5859 0.97 41349 4729 2 1081.583805 541.8002 Denticleless protein homolog OS=Homo sapiens OX=9606 GN=DTL PE=1 SV=3 5.84 1531.8 - 994721 - - - -1.9259 - 2.134 0.462 - 279 1 2 0 -0.0021 11 0 0 0 2.26E+07 2.32E+07 - - - 4.5032 0.9997 221125_WJC_METTL3_EV_vs_WT_F04.04732.04732.2 0.000302 18-Oct R.GGAGVGSMTK.L sp|P39019|RS19_HUMAN 1 863.4171 1.15 41351 4732 2 863.415182 432.7158 40S ribosomal protein S19 OS=Homo sapiens OX=9606 GN=RPS19 PE=1 SV=2 8.75 1532.2 - 4.31E+07 - - - -2.2237 - 2.038 0.49 - 527.2 1 2 0 -0.0019 10 0 0 0 6.71E+08 5.83E+08 - - - 4.6469 0.959 221125_WJC_METTL3_EV_vs_WT_F04.04735.04735.2 6.98 14-Aug R.AGGPGLER[166.11].G "sp|O75369|FLNB_HUMAN,sp|P21333|FLNA_HUMAN,tr|A0A7P0NMY4|A0A7P0NMY4_HUMAN,tr|Q60FE5|Q60FE5_HUMAN,tr|H0Y5C6|H0Y5C6_HUMAN,tr|E7EN95|E7EN95_HUMAN,tr|A0A804HK76|A0A804HK76_HUMAN,tr|H7C5L4|H7C5L4_HUMAN,tr|A0A804HL72|A0A804HL72_HUMAN" 9 765.4009 0.001 41353 4735 2 765.400373 383.7077 Filamin-B OS=Homo sapiens OX=9606 GN=FLNB PE=1 SV=2 6.05 1532.4 - 6.81E+06 - - - -0.6519 - 1.162 0.032 - 167.7 1 2 0 -0.0005 8 0 0 0 0.00E+00 5.09E+08 - - - -0.27 0.9996 221125_WJC_METTL3_EV_vs_WT_F04.04741.04741.2 0.00591 20-Dec K.LVTAAGDQTAK.F "sp|Q9NZJ0|DTL_HUMAN,tr|F5GZ90|F5GZ90_HUMAN" 2 1073.5717 0.97 41357 4741 2 1073.569569 537.7931 Denticleless protein homolog OS=Homo sapiens OX=9606 GN=DTL PE=1 SV=3 5.84 1533 - 1.54E+06 - - - -1.9738 - 2.221 0.403 - 440.9 1 2 0 -0.0021 11 0 0 0 2.26E+07 2.32E+07 - - - 4.1756 0.9602 221125_WJC_METTL3_EV_vs_WT_F04.04744.04744.2 39.3 16-Jun K.EGIPPDQQR.L "sp|P62979|RS27A_HUMAN,sp|P0CG48|UBC_HUMAN,sp|P0CG48|UBC_HUMAN,sp|P0CG48|UBC_HUMAN,sp|P0CG48|UBC_HUMAN,sp|P0CG48|UBC_HUMAN,sp|P0CG48|UBC_HUMAN,sp|P0CG48|UBC_HUMAN,sp|P0CG48|UBC_HUMAN,sp|P0CG48|UBC_HUMAN,sp|P0CG47|UBB_HUMAN,sp|P0CG47|UBB_HUMAN,sp|P0CG47|UBB_HUMAN,sp|P62987|RL40_HUMAN,tr|F5H388|F5H388_HUMAN,tr|F5H388|F5H388_HUMAN,tr|F5GYU3|F5GYU3_HUMAN,tr|F5GYU3|F5GYU3_HUMAN,tr|B4DV12|B4DV12_HUMAN,tr|B4DV12|B4DV12_HUMAN,tr|J3QSA3|J3QSA3_HUMAN,tr|Q5PY61|Q5PY61_HUMAN,tr|Q5PY61|Q5PY61_HUMAN,tr|Q5PY61|Q5PY61_HUMAN,tr|F5H2Z3|F5H2Z3_HUMAN,tr|F5H2Z3|F5H2Z3_HUMAN,tr|M0R2S1|M0R2S1_HUMAN,tr|J3QS39|J3QS39_HUMAN,tr|J3QTR3|J3QTR3_HUMAN,tr|Q96C32|Q96C32_HUMAN,tr|Q96C32|Q96C32_HUMAN,tr|Q96C32|Q96C32_HUMAN,tr|Q96C32|Q96C32_HUMAN,tr|M0R1V7|M0R1V7_HUMAN,tr|F5H747|F5H747_HUMAN,tr|F5H747|F5H747_HUMAN,tr|F5GXK7|F5GXK7_HUMAN,tr|F5GXK7|F5GXK7_HUMAN,tr|M0R1M6|M0R1M6_HUMAN,tr|F5H6Q2|F5H6Q2_HUMAN,tr|F5H6Q2|F5H6Q2_HUMAN,tr|F5GZ39|F5GZ39_HUMAN,tr|J3QKN0|J3QKN0_HUMAN,tr|J3QKN0|J3QKN0_HUMAN,tr|J3QKN0|J3QKN0_HUMAN,tr|F5H265|F5H265_HUMAN,tr|F5H265|F5H265_HUMAN,tr|A0A2R8Y422|A0A2R8Y422_HUMAN" 48 1038.5094 0.06 41359 4744 2 1038.509921 520.262 Ubiquitin-40S ribosomal protein S27a OS=Homo sapiens OX=9606 GN=RPS27A PE=1 SV=2 4.37 1533.3 - 465818 - - - 0.4795 - 1.079 0.086 - 83.6 2 2 0 0.0005 9 0 0 0 3.74E+07 6.01E+08 - - - -0.2385 0.9905 221125_WJC_METTL3_EV_vs_WT_F04.04759.04759.2 0.138 12-Jul R.APQALER.Y sp|Q7Z5L9|I2BP2_HUMAN 1 783.4239 1.56 41365 4759 2 783.421383 392.7192 Interferon regulatory factor 2-binding protein 2 OS=Homo sapiens OX=9606 GN=IRF2BP2 PE=1 SV=2 6.05 1535.4 - 1.38E+07 - - - -3.2154 - 1.502 0.208 - 219.4 1 2 0 -0.0025 7 0 0 0 3.98E+08 2.55E+08 - - - 1.8655 0.7734 221125_WJC_METTL3_EV_vs_WT_F04.04786.04786.2 1.6 12-Jul R.QAVTNLK.E "sp|Q15643|TRIPB_HUMAN,tr|H0YJ97|H0YJ97_HUMAN" 2 772.4443 0.95 41377 4786 2 772.441747 387.2294 Thyroid receptor-interacting protein 11 OS=Homo sapiens OX=9606 GN=TRIP11 PE=1 SV=3 8.75 1538.5 - 6.54E+06 - - - -3.309 - 1.12 0.023 - 203.9 1 2 0 -0.0026 7 0 0 0 4.13E+08 4.36E+08 - - - -0.4308 0.9852 221125_WJC_METTL3_EV_vs_WT_F04.04789.04789.2 0.0536 12-Jun K.VETEYAR.F "sp|P28347|TEAD1_HUMAN,sp|Q15561|TEAD4_HUMAN,sp|Q99594|TEAD3_HUMAN,tr|A0A1X7SBS4|A0A1X7SBS4_HUMAN,tr|E9PKB7|E9PKB7_HUMAN,tr|Q53GI4|Q53GI4_HUMAN,tr|H0YE88|H0YE88_HUMAN,tr|H0YEJ9|H0YEJ9_HUMAN,tr|A0A0A0MRF3|A0A0A0MRF3_HUMAN,tr|A0A7P0SNI2|A0A7P0SNI2_HUMAN" 10 866.4134 0.56 41378 4789 2 866.410936 434.214 Transcriptional enhancer factor TEF-1 OS=Homo sapiens OX=9606 GN=TEAD1 PE=1 SV=2 4.53 1538.9 - 3.35E+06 - - - -2.8404 - 1.305 0.193 - 125.7 1 2 0 -0.0025 7 0 0 0 1.52E+08 2.74E+08 - - - 1.3092 0.9866 221125_WJC_METTL3_EV_vs_WT_F04.04790.04790.2 0.0461 16-Aug K.LQSSEAEVR[166.11].S "sp|Q9P2E9|RRBP1_HUMAN,tr|A0A087WVV2|A0A087WVV2_HUMAN,tr|F8W7S5|F8W7S5_HUMAN" 3 1027.5174 0.83 41379 4790 2 1027.51354 514.766 Ribosome-binding protein 1 OS=Homo sapiens OX=9606 GN=RRBP1 PE=1 SV=5 4.53 1539.1 - 1.49E+06 - - - -3.7158 - 1.682 0.181 - 197.4 1 2 0 -0.0038 9 0 0 0 1.19E+08 1.45E+08 - - - 1.881 0.8727 221125_WJC_METTL3_EV_vs_WT_F04.04796.04796.2 0.0262 14-Aug Q.AASSYGVR.A sp|Q96PK6|RBM14_HUMAN 1 809.4032 1.65 41381 4796 2 809.400156 405.7089 RNA-binding protein 14 OS=Homo sapiens OX=9606 GN=RBM14 PE=1 SV=2 8.79 1539.8 - 2.30E+06 - - - -3.7188 - 1.719 0.383 - 297.4 1 1 0 -0.003 8 0 0 0 7.42E+07 4.49E+07 - - - 3.5028 0.9868 221125_WJC_METTL3_EV_vs_WT_F04.04798.04798.2 0.608 14-Jul K.AMDEMNGK[136.11].E "sp|O43390|HNRPR_HUMAN,tr|B4DT28|B4DT28_HUMAN,tr|A0A6Q8PH35|A0A6Q8PH35_HUMAN,tr|A0A286YEZ8|A0A286YEZ8_HUMAN" 4 902.3717 1.64 41383 4798 2 902.37072 452.1931 Heterogeneous nuclear ribonucleoprotein R OS=Homo sapiens OX=9606 GN=HNRNPR PE=1 SV=1 4.37 1540 - 1.24E+06 - - - -1.1281 - 0.927 0.241 - 135.2 1 2 0 -0.001 8 0 0 0 3.15E+07 1.92E+07 - - - 0.5921 0.9967 221125_WJC_METTL3_EV_vs_WT_F04.04801.04801.2 1.36 16-Sep K.VLENAEGAR[166.11].T "sp|P38646|GRP75_HUMAN,tr|H0Y8K0|H0Y8K0_HUMAN,tr|A0A7I2V2S7|A0A7I2V2S7_HUMAN,tr|A0A7I2V2G2|A0A7I2V2G2_HUMAN,tr|A0A3B3ITI4|A0A3B3ITI4_HUMAN,tr|A0A7I2V3F7|A0A7I2V3F7_HUMAN,tr|D6RCD7|D6RCD7_HUMAN" 7 967.4962 0.45 41384 4801 2 967.494957 484.7554 "Stress-70 protein, mitochondrial OS=Homo sapiens OX=9606 GN=HSPA9 PE=1 SV=2" 4.53 1540.4 - 2.44E+07 - - - -1.3147 - 1.463 0.205 - 321.6 1 2 0 -0.0013 9 0 0 0 1.37E+09 3.04E+09 - - - 1.6555 0.9896 221125_WJC_METTL3_EV_vs_WT_F04.04802.04802.2 0.00923 16-Jul K.VLENAEGAR.T "sp|P38646|GRP75_HUMAN,tr|H0Y8K0|H0Y8K0_HUMAN,tr|A0A7I2V2S7|A0A7I2V2S7_HUMAN,tr|A0A7I2V2G2|A0A7I2V2G2_HUMAN,tr|A0A3B3ITI4|A0A3B3ITI4_HUMAN,tr|A0A7I2V3F7|A0A7I2V3F7_HUMAN,tr|D6RCD7|D6RCD7_HUMAN" 7 957.488 0.45 41385 4802 2 957.484633 479.7513 "Stress-70 protein, mitochondrial OS=Homo sapiens OX=9606 GN=HSPA9 PE=1 SV=2" 4.53 1540.4 - 9.72E+06 - - - -3.4737 - 1.537 0.225 - 171.2 1 2 0 -0.0033 9 0 0 0 1.37E+09 3.04E+09 - - - 1.9453 0.9994 221125_WJC_METTL3_EV_vs_WT_F04.04807.04807.2 0.0109 16-Oct K.LQSSEAEVR.S "sp|Q9P2E9|RRBP1_HUMAN,tr|A0A087WVV2|A0A087WVV2_HUMAN,tr|F8W7S5|F8W7S5_HUMAN" 3 1017.5091 0.83 41386 4807 2 1017.507885 509.7618 Ribosome-binding protein 1 OS=Homo sapiens OX=9606 GN=RRBP1 PE=1 SV=5 4.53 1541.2 - 5.22E+06 - - - -1.1823 - 1.893 0.293 - 347.9 1 2 0 -0.0012 9 0 0 0 1.19E+08 1.43E+08 - - - 3.051 0.9988 221125_WJC_METTL3_EV_vs_WT_F04.04814.04814.2 0.254 16-Aug K.YIASQADDR.S sp|P54198|HIRA_HUMAN 1 1037.4778 1.09 41389 4814 2 1037.476829 519.7462 Protein HIRA OS=Homo sapiens OX=9606 GN=HIRA PE=1 SV=2 4.21 1542.2 - 889522 - - - -0.9244 - 1.417 0.311 - 216.5 1 2 0 -0.001 9 0 0 0 1.96E+07 1.79E+07 - - - 2.3461 0.9944 221125_WJC_METTL3_EV_vs_WT_F04.04819.04819.2 0.00242 12-Jun R.YSQIC[160.03]AK.V "sp|Q5VTU8|AT5EL_HUMAN,sp|P56381|ATP5E_HUMAN" 2 868.4113 1.04 41392 4819 2 868.407446 435.2129 "ATP synthase subunit epsilon-like protein, mitochondrial OS=Homo sapiens OX=9606 GN=ATP5F1EP2 PE=1 SV=1" 8.2 1542.7 - 3.06E+06 - - - -4.4253 - 1.479 0.389 - 85.2 1 2 0 -0.0038 7 0 0 0 2.71E+08 2.61E+08 - - - 3.153 0.9735 221125_WJC_METTL3_EV_vs_WT_F04.04820.04820.2 0.496 16-Jun R.AITEASPAH.- "sp|Q9H7Z7|PGES2_HUMAN,tr|A0A7I2V5T7|A0A7I2V5T7_HUMAN,tr|A6NHH0|A6NHH0_HUMAN" 3 895.4399 - 41393 4820 2 895.437209 448.7272 Prostaglandin E synthase 2 OS=Homo sapiens OX=9606 GN=PTGES2 PE=1 SV=1 5.24 1542.7 - 2.24E+06 - - - -3.0566 - 1.195 0.195 - 80.9 1 2 0 -0.0027 9 0 0 0 - - - - - 0.9958 0.9998 221125_WJC_METTL3_EV_vs_WT_F04.04825.04825.2 0.000298 16-Aug K.LETADAPAR[166.11].L "sp|O14654|IRS4_HUMAN,tr|A0A804CF45|A0A804CF45_HUMAN" 2 952.4853 0.84 41396 4825 2 952.485283 477.2499 Insulin receptor substrate 4 OS=Homo sapiens OX=9606 GN=IRS4 PE=1 SV=1 4.37 1543.2 - 6.42E+06 - - - -0.0493 - 1.808 0.472 - 228.7 1 2 0 0 9 0 0 0 2.46E+08 2.94E+08 - - - 4.2405 0.9861 221125_WJC_METTL3_EV_vs_WT_F04.04828.04828.2 2.97 12-Jun K.VTQDELK[136.11].E "sp|P19338|NUCL_HUMAN,tr|A0A7I2V506|A0A7I2V506_HUMAN,tr|A0A7I2V2U7|A0A7I2V2U7_HUMAN,tr|A0A7I2V3F3|A0A7I2V3F3_HUMAN,tr|A0A7I2V428|A0A7I2V428_HUMAN,tr|A0A7I2V349|A0A7I2V349_HUMAN,tr|H7BY16|H7BY16_HUMAN,tr|A0A7I2V5M5|A0A7I2V5M5_HUMAN,tr|C9JLB1|C9JLB1_HUMAN" 9 839.448 0.86 41398 4828 2 839.445826 420.7313 Nucleolin OS=Homo sapiens OX=9606 GN=NCL PE=1 SV=3 4.37 1543.5 - 5.02E+07 - - - -2.5874 - 1.357 0.182 - 96.3 2 2 0 -0.0022 7 0 0 0 1.58E+09 1.85E+09 - - - 1.2174 0.9351 221125_WJC_METTL3_EV_vs_WT_F04.04834.04834.2 0.0385 14-Jul K.SEPVVSTR[166.11].K "sp|Q9NRY5|F1142_HUMAN,tr|E5RHI8|E5RHI8_HUMAN,tr|E5RHP2|E5RHP2_HUMAN,tr|E5RGF9|E5RGF9_HUMAN,tr|E5RFK2|E5RFK2_HUMAN,tr|E5RK42|E5RK42_HUMAN,tr|E5RH43|E5RH43_HUMAN" 7 883.4639 1.47 41399 4834 2 883.458969 442.7392 Protein FAM114A2 OS=Homo sapiens OX=9606 GN=FAM114A2 PE=1 SV=4 5.72 1544.4 - 3.22E+06 - - - -5.543 - 1.232 0.266 - 205.9 1 2 0 -0.0049 8 0 0 0 1.88E+08 1.28E+08 - - - 1.6334 0.9994 221125_WJC_METTL3_EV_vs_WT_F04.04836.04836.2 0.0106 16-Oct K.LETADAPAR.L "sp|O14654|IRS4_HUMAN,tr|A0A804CF45|A0A804CF45_HUMAN" 2 942.4771 0.84 41400 4836 2 942.47488 472.2458 Insulin receptor substrate 4 OS=Homo sapiens OX=9606 GN=IRS4 PE=1 SV=1 4.37 1544.6 - 1.14E+07 - - - -2.3131 - 1.805 0.426 - 373.6 1 2 0 -0.0022 9 0 0 0 2.46E+08 2.94E+08 - - - 3.8953 0.9959 221125_WJC_METTL3_EV_vs_WT_F04.04837.04837.2 0.0131 16-Jul R.ALEEEQEAR.E "sp|Q7Z406|MYH14_HUMAN,tr|A1L2Z2|A1L2Z2_HUMAN" 2 1073.4989 2.52 41401 4837 2 1073.497236 537.7567 Myosin-14 OS=Homo sapiens OX=9606 GN=MYH14 PE=1 SV=2 4.09 1544.7 - 469978 - - - -1.5659 - 1.263 0.256 - 115.6 1 2 0 -0.0017 9 0 0 0 8.92E+06 3.54E+06 - - - 1.6068 0.9874 221125_WJC_METTL3_EV_vs_WT_F04.04849.04849.2 0.72 14-Jun R.LEQDSSLK[136.11].S sp|Q8N0V3|RBFA_HUMAN 1 926.48 3.47 41408 4849 2 926.47925 464.2473 "Putative ribosome-binding factor A, mitochondrial OS=Homo sapiens OX=9606 GN=RBFA PE=1 SV=3" 4.37 1546 - 1.89E+06 - - - -0.8376 - 1.281 0.102 - 84.8 1 2 0 -0.0008 8 0 0 0 1.18E+08 3.40E+07 - - - 0.541 0.8933 221125_WJC_METTL3_EV_vs_WT_F04.04850.04850.2 2.76 20-May R.VEGSGDPEEGK.M "sp|P29597|TYK2_HUMAN,tr|E9PM19|E9PM19_HUMAN,tr|H0YCT7|H0YCT7_HUMAN,tr|E9PPF2|E9PPF2_HUMAN" 4 1102.4778 999 41409 4850 2 1102.47456 552.2462 Non-receptor tyrosine-protein kinase TYK2 OS=Homo sapiens OX=9606 GN=TYK2 PE=1 SV=3 4 1546.1 - 1.11E+06 - - - -2.9824 - 1.145 0.114 - 97.2 4 2 0 -0.0033 11 0 0 0 4.11E+07 0.00E+00 - - - -0.0207 0.9926 221125_WJC_METTL3_EV_vs_WT_F04.04863.04863.2 0.104 12-May R.QQGDLVR.K "sp|P41250|GARS_HUMAN,tr|H7C443|H7C443_HUMAN,tr|A0A6Q8PGA8|A0A6Q8PGA8_HUMAN,tr|A0A6Q8PGZ8|A0A6Q8PGZ8_HUMAN,tr|A0A6Q8PFU7|A0A6Q8PFU7_HUMAN,tr|A0A6Q8PH49|A0A6Q8PH49_HUMAN,tr|A0A6Q8PGT3|A0A6Q8PGT3_HUMAN,tr|A0A6Q8PF45|A0A6Q8PF45_HUMAN,tr|A0A6Q8PFV5|A0A6Q8PFV5_HUMAN,tr|A0A6Q8PGN7|A0A6Q8PGN7_HUMAN,tr|A0A6Q8PGZ9|A0A6Q8PGZ9_HUMAN,tr|A0A6Q8PHI7|A0A6Q8PHI7_HUMAN,tr|A0A6Q8PFZ6|A0A6Q8PFZ6_HUMAN,tr|F8WCK4|F8WCK4_HUMAN" 14 814.4297 1.22 41414 4863 2 814.427998 408.2221 Glycine--tRNA ligase OS=Homo sapiens OX=9606 GN=GARS1 PE=1 SV=3 5.84 1547.7 - 5.19E+06 - - - -2.1095 - 1.21 0.242 - 163.4 1 2 0 -0.0017 7 0 0 0 1.17E+08 9.63E+07 - - - 1.4319 0.9914 221125_WJC_METTL3_EV_vs_WT_F04.04864.04864.2 1.65 12-Jul K.YLC[160.03]DEQK[136.11].E "sp|Q04637|IF4G1_HUMAN,tr|E7EUU4|E7EUU4_HUMAN,tr|E9PGM1|E9PGM1_HUMAN,tr|E7EX73|E7EX73_HUMAN,tr|A0A7I2Y1C3|A0A7I2Y1C3_HUMAN" 5 962.4259 0.46 41415 4864 2 962.424789 482.2202 Eukaryotic translation initiation factor 4 gamma 1 OS=Homo sapiens OX=9606 GN=EIF4G1 PE=1 SV=4 4.37 1547.9 - 405806 - - - -1.1367 - 0.862 0.314 - 133.1 1 2 0 -0.0011 7 0 0 0 5.71E+06 1.25E+07 - - - 0.8893 0.9994 221125_WJC_METTL3_EV_vs_WT_F04.04868.04868.2 0.0129 14-Jul R.EALAAEDR.E "sp|Q15643|TRIPB_HUMAN,tr|H0YJI2|H0YJI2_HUMAN,tr|H0YJ97|H0YJ97_HUMAN" 3 873.4192 1.21 41417 4868 2 873.418186 437.7169 Thyroid receptor-interacting protein 11 OS=Homo sapiens OX=9606 GN=TRIP11 PE=1 SV=3 4.14 1548.4 - 7.78E+06 - - - -1.1735 - 1.567 0.368 - 211.5 1 2 0 -0.001 8 0 0 0 1.92E+08 1.59E+08 - - - 3.1134 0.9956 221125_WJC_METTL3_EV_vs_WT_F04.04869.04869.2 0.518 14-Sep R.EALAAEDR[166.11].E "sp|Q15643|TRIPB_HUMAN,tr|H0YJI2|H0YJI2_HUMAN,tr|H0YJ97|H0YJ97_HUMAN" 3 883.4275 1.36 41418 4869 2 883.425887 442.721 Thyroid receptor-interacting protein 11 OS=Homo sapiens OX=9606 GN=TRIP11 PE=1 SV=3 4.14 1548.4 - 6.12E+06 - - - -1.8043 - 1.827 0.129 - 361.4 2 2 0 -0.0016 8 0 0 0 2.19E+08 1.61E+08 - - - 1.6765 0.9408 221125_WJC_METTL3_EV_vs_WT_F04.04877.04877.2 0.0644 18-Oct R.PITTGNSPPR.Y "sp|P27694|RFA1_HUMAN,tr|I3L2M5|I3L2M5_HUMAN,tr|I3L524|I3L524_HUMAN" 3 1038.5458 1.53 41424 4877 2 1038.545398 520.2802 Replication protein A 70 kDa DNA-binding subunit OS=Homo sapiens OX=9606 GN=RPA1 PE=1 SV=2 10.18 1549.2 - 376938 - - - -0.3948 - 1.604 0.268 - 305 1 1 0 -0.0004 10 0 0 0 2.72E+07 1.78E+07 - - - 2.3392 0.9852 221125_WJC_METTL3_EV_vs_WT_F04.04883.04883.2 0.0296 14-Sep K.VPEPC[160.03]QPK.V "sp|P35321|SPR1A_HUMAN,sp|P22528|SPR1B_HUMAN" 2 953.4641 116.68 41428 4883 2 953.459269 477.7393 Cornifin-A OS=Homo sapiens OX=9606 GN=SPRR1A PE=1 SV=2 5.97 1549.8 - 3.43E+06 - - - -5.0164 - 1.411 0.342 - 306.4 1 2 0 -0.0048 8 0 0 0 1.49E+08 1.28E+06 - - - 2.6039 0.9991 221125_WJC_METTL3_EV_vs_WT_F04.04886.04886.2 0.0817 14-Sep K.LENEVEQR[166.11].H sp|P12270|TPR_HUMAN 1 1025.5017 1.3 41431 4886 2 1025.500829 513.7581 Nucleoprotein TPR OS=Homo sapiens OX=9606 GN=TPR PE=1 SV=3 4.25 1550 - 473893 - - - -0.8571 - 1.616 0.277 - 334 1 2 0 -0.0009 8 0 0 0 1.35E+08 1.04E+08 - - - 2.5342 0.9903 221125_WJC_METTL3_EV_vs_WT_F04.04901.04901.2 1.08 14-Jul R.GINGVSPK[136.11].V "sp|P18124|RL7_HUMAN,tr|C9JIJ5|C9JIJ5_HUMAN,tr|C9JZ88|C9JZ88_HUMAN,tr|A8MUD9|A8MUD9_HUMAN" 4 778.4429 1.53 41442 4901 2 778.442056 390.2287 60S ribosomal protein L7 OS=Homo sapiens OX=9606 GN=RPL7 PE=1 SV=1 8.75 1551.6 - 4.64E+06 - - - -1.0238 - 1.167 0.171 - 144.8 1 2 0 -0.0008 8 0 0 0 2.11E+08 1.38E+08 - - - 0.7695 0.9716 221125_WJC_METTL3_EV_vs_WT_F04.04902.04902.2 0.739 12-Jul R.QIIGQAK[136.11].K sp|O00483|NDUA4_HUMAN 1 764.4636 0.03 41443 4902 2 764.463302 383.2391 Cytochrome c oxidase subunit NDUFA4 OS=Homo sapiens OX=9606 GN=NDUFA4 PE=1 SV=1 8.75 1551.7 - 1.41E+06 - - - -0.3741 - 1.289 0.012 - 132.6 1 2 0 -0.0003 7 0 0 0 1.02E+06 3.70E+07 - - - -0.0661 0.9684 221125_WJC_METTL3_EV_vs_WT_F04.04903.04903.2 0.00807 18-Oct R.PITTGNSPPR[166.11].Y "sp|P27694|RFA1_HUMAN,tr|I3L2M5|I3L2M5_HUMAN,tr|I3L524|I3L524_HUMAN" 3 1048.5541 1.53 41444 4903 2 1048.553712 525.2843 Replication protein A 70 kDa DNA-binding subunit OS=Homo sapiens OX=9606 GN=RPA1 PE=1 SV=2 10.18 1551.8 - 543531 - - - -0.3491 - 1.802 0.306 - 319.5 1 1 0 -0.0004 10 0 0 0 2.73E+07 1.78E+07 - - - 2.9448 0.9992 221125_WJC_METTL3_EV_vs_WT_F04.04907.04907.2 0.0266 18-Sep R.AQLGGPEAAK.S "sp|P04792|HSPB1_HUMAN,tr|A0A6Q8PFK8|A0A6Q8PFK8_HUMAN,tr|C9J3N8|C9J3N8_HUMAN,tr|A0A6Q8PGK1|A0A6Q8PGK1_HUMAN" 4 940.4978 1.96 41446 4907 2 940.497429 471.2562 Heat shock protein beta-1 OS=Homo sapiens OX=9606 GN=HSPB1 PE=1 SV=2 6.05 1552.3 - 1.70E+07 - - - -0.3892 - 1.713 0.276 - 263.3 1 2 0 -0.0004 10 0 0 0 1.49E+09 7.59E+08 - - - 2.5818 0.9889 221125_WJC_METTL3_EV_vs_WT_F04.04908.04908.2 0.848 12-Aug K.QVEQLEK[136.11].E sp|Q14152|EIF3A_HUMAN 1 880.4745 1.45 41447 4908 2 880.474018 441.2445 Eukaryotic translation initiation factor 3 subunit A OS=Homo sapiens OX=9606 GN=EIF3A PE=1 SV=1 4.53 1552.3 - 5.86E+06 - - - -0.6008 - 1.418 0.059 - 267.1 1 2 0 -0.0005 7 0 0 0 2.09E+08 1.44E+08 - - - 0.5832 0.9723 221125_WJC_METTL3_EV_vs_WT_F04.04910.04910.2 0.0167 18-Oct S.LAATAQAAPR.L "sp|Q96PU8|QKI_HUMAN,tr|H0YG47|H0YG47_HUMAN,tr|H0YGD6|H0YGD6_HUMAN" 3 968.5403 1.51 41449 4910 2 968.539444 485.2774 Protein quaking OS=Homo sapiens OX=9606 GN=QKI PE=1 SV=1 9.75 1552.6 - 491617 - - - -0.9137 - 2.192 0.27 - 344.4 1 1 0 -0.0009 10 0 0 0 3.15E+07 2.08E+07 - - - 3.2256 0.9969 221125_WJC_METTL3_EV_vs_WT_F04.04913.04913.2 0.124 18-Aug R.AQLGGPEAAK[136.11].S "sp|P04792|HSPB1_HUMAN,tr|A0A6Q8PFK8|A0A6Q8PFK8_HUMAN,tr|C9J3N8|C9J3N8_HUMAN,tr|A0A6Q8PGK1|A0A6Q8PGK1_HUMAN" 4 948.512 2.01 41450 4913 2 948.510178 475.2633 Heat shock protein beta-1 OS=Homo sapiens OX=9606 GN=HSPB1 PE=1 SV=2 6.05 1553 - 1.21E+07 - - - -1.9156 - 1.513 0.247 - 211.1 1 2 0 -0.0018 10 0 0 0 1.54E+09 7.65E+08 - - - 2.0206 0.9666 221125_WJC_METTL3_EV_vs_WT_F04.04914.04914.2 0.403 12-Jun K.VQALEQR.N sp|Q6KB66|K2C80_HUMAN 1 842.461 0.92 41451 4914 2 842.460661 422.2378 "Keratin, type II cytoskeletal 80 OS=Homo sapiens OX=9606 GN=KRT80 PE=1 SV=2" 5.97 1553 - 7.30E+06 - - - -0.4214 - 1.284 0 - 128.1 1 2 0 -0.0004 7 0 0 0 1.33E+08 1.45E+08 - - - -0.167 0.9949 221125_WJC_METTL3_EV_vs_WT_F04.04919.04919.2 0.0797 12-Jul R.NQTQVLR[166.11].Q sp|Q96CS3|FAF2_HUMAN 1 867.4802 1.26 41454 4919 2 867.479686 434.7474 FAS-associated factor 2 OS=Homo sapiens OX=9606 GN=FAF2 PE=1 SV=2 9.75 1553.5 - 2.50E+06 - - - -0.5752 - 1.318 0.162 - 226.1 1 2 0 -0.0005 7 0 0 0 7.75E+07 6.14E+07 - - - 1.1123 0.9835 221125_WJC_METTL3_EV_vs_WT_F04.04920.04920.2 1.73 14-Jun K.AGMTHIVR[166.11].E "sp|P39023|RL3_HUMAN,tr|H7C3M2|H7C3M2_HUMAN,tr|F8WCR1|F8WCR1_HUMAN,tr|H7C422|H7C422_HUMAN" 4 893.4781 5.09 41455 4920 2 893.477673 447.7463 60S ribosomal protein L3 OS=Homo sapiens OX=9606 GN=RPL3 PE=1 SV=2 9.8 1553.6 - 1.61E+06 - - - -0.451 - 1.13 0.12 - 155.5 1 2 0 -0.0004 8 0 0 0 9.72E+07 1.91E+07 - - - 0.2958 0.9962 221125_WJC_METTL3_EV_vs_WT_F04.04921.04921.2 0.204 16-Nov R.QLAEEDAAR[166.11].Q sp|Q15149|PLEC_HUMAN 1 1011.4861 1.66 41456 4921 2 1011.482777 506.7503 Plectin OS=Homo sapiens OX=9606 GN=PLEC PE=1 SV=3 4.14 1553.7 - 263118 - - - -3.2437 - 1.918 0.236 - 269.2 1 2 0 -0.0033 9 0 0 0 3.47E+07 2.08E+07 - - - 2.6673 0.9916 221125_WJC_METTL3_EV_vs_WT_F04.04925.04925.2 0.688 12-Jun R.EEEELAR.R "sp|Q6Y7W6|GGYF2_HUMAN,tr|A0A7I2V3H7|A0A7I2V3H7_HUMAN,tr|I1E4Y6|I1E4Y6_HUMAN,tr|A0A7I2V516|A0A7I2V516_HUMAN,tr|A0A7I2V3H0|A0A7I2V3H0_HUMAN,tr|A0A7I2V361|A0A7I2V361_HUMAN,tr|E7ESB6|E7ESB6_HUMAN" 7 874.4032 1.44 41459 4925 2 874.402345 438.2089 GRB10-interacting GYF protein 2 OS=Homo sapiens OX=9606 GN=GIGYF2 PE=1 SV=1 4.09 1554.2 - 2.27E+07 - - - -1.0075 - 1.464 0.083 - 248.4 1 2 0 -0.0009 7 0 0 0 2.81E+08 1.94E+08 - - - 0.8615 0.9994 221125_WJC_METTL3_EV_vs_WT_F04.04930.04930.2 0.0185 14-Jul R.IYDETQGR.Q "sp|A6NHR9|SMHD1_HUMAN,tr|A0A2R8YCU7|A0A2R8YCU7_HUMAN,tr|J3KTL8|J3KTL8_HUMAN" 3 980.4563 0.56 41463 4930 2 980.455246 491.2354 Structural maintenance of chromosomes flexible hinge domain-containing protein 1 OS=Homo sapiens OX=9606 GN=SMCHD1 PE=1 SV=2 4.37 1554.6 - 1.54E+06 - - - -1.0995 - 1.653 0.348 - 154.4 1 2 0 -0.0011 8 0 0 0 2.11E+07 3.79E+07 - - - 3.1268 0.9981 221125_WJC_METTL3_EV_vs_WT_F04.04931.04931.2 0.0364 16-Aug R.QLAEEDAAR.Q sp|Q15149|PLEC_HUMAN 1 1001.4778 1.66 41464 4931 2 1001.475875 501.7462 Plectin OS=Homo sapiens OX=9606 GN=PLEC PE=1 SV=3 4.14 1554.7 - 896371 - - - -1.9102 - 1.704 0.25 - 256.6 1 2 0 -0.0019 9 0 0 0 3.47E+07 2.08E+07 - - - 2.4288 0.9137 221125_WJC_METTL3_EV_vs_WT_F04.04934.04934.2 0.00185 20-Sep Y.LATAADDSSVK.L sp|Q9UMS4|PRP19_HUMAN 1 1076.535 1.17 41467 4934 2 1076.530677 539.2748 Pre-mRNA-processing factor 19 OS=Homo sapiens OX=9606 GN=PRPF19 PE=1 SV=1 4.21 1555.1 - 203495 - - - -3.9869 - 1.986 0.462 - 241.7 1 1 0 -0.0043 11 0 0 0 1.18E+07 1.01E+07 - - - 4.3081 0.9991 221125_WJC_METTL3_EV_vs_WT_F04.04938.04938.2 0.0302 14-Jul R.VLVNDAQK[136.11].V sp|Q13263|TIF1B_HUMAN 1 893.5062 0.8 41468 4938 2 893.505581 447.7604 Transcription intermediary factor 1-beta OS=Homo sapiens OX=9606 GN=TRIM28 PE=1 SV=5 5.81 1555.6 - 5.60E+06 - - - -0.6726 - 1.379 0.338 - 151 1 2 0 -0.0006 8 0 0 0 2.71E+08 3.41E+08 - - - 2.5065 0.9977 221125_WJC_METTL3_EV_vs_WT_F04.04940.04940.2 0.143 16-May R.VISTTDAER.Q "sp|O95394|AGM1_HUMAN,tr|A0A494C1E2|A0A494C1E2_HUMAN,tr|J3KN95|J3KN95_HUMAN,tr|A0A494C0G1|A0A494C0G1_HUMAN,tr|A0A494C1Q4|A0A494C1Q4_HUMAN,tr|H0Y8I3|H0Y8I3_HUMAN,tr|H0Y987|H0Y987_HUMAN,tr|A0A087WT27|A0A087WT27_HUMAN" 8 990.4982 0.81 41469 4940 2 990.498108 496.2564 Phosphoacetylglucosamine mutase OS=Homo sapiens OX=9606 GN=PGM3 PE=1 SV=1 4.37 1555.8 - 953235 - - - -0.0818 - 1.164 0.299 - 53.8 1 2 0 -0.0001 9 0 0 0 2.97E+07 3.65E+07 - - - 1.6887 0.9183 221125_WJC_METTL3_EV_vs_WT_F04.04951.04951.2 4.66 16-Apr R.VISTTDAER[166.11].Q "sp|O95394|AGM1_HUMAN,tr|A0A494C1E2|A0A494C1E2_HUMAN,tr|J3KN95|J3KN95_HUMAN,tr|A0A494C0G1|A0A494C0G1_HUMAN,tr|A0A494C1Q4|A0A494C1Q4_HUMAN,tr|H0Y8I3|H0Y8I3_HUMAN,tr|H0Y987|H0Y987_HUMAN,tr|A0A087WT27|A0A087WT27_HUMAN" 8 1000.5065 0.81 41474 4951 2 1000.505095 501.2605 Phosphoacetylglucosamine mutase OS=Homo sapiens OX=9606 GN=PGM3 PE=1 SV=1 4.37 1557.1 - 2.60E+06 - - - -1.3633 - 0.995 0.11 - 39.1 7 2 0 -0.0014 9 0 0 0 2.97E+07 3.65E+07 - - - -0.539 0.8283 221125_WJC_METTL3_EV_vs_WT_F04.04953.04953.2 0.000484 20-Dec A.AAAAAATPAVR[166.11].T "sp|Q9H361|PABP3_HUMAN,sp|P11940|PABP1_HUMAN,tr|H0YAS6|H0YAS6_HUMAN,tr|H0YB75|H0YB75_HUMAN,tr|H0YAS7|H0YAS7_HUMAN,tr|A0A7I2YQE4|A0A7I2YQE4_HUMAN,tr|H0YAW6|H0YAW6_HUMAN,tr|A0A7I2V649|A0A7I2V649_HUMAN,tr|H0YAR2|H0YAR2_HUMAN,tr|E7ERJ7|E7ERJ7_HUMAN,tr|A0A7I2YQ88|A0A7I2YQ88_HUMAN,tr|A0A087WTT1|A0A087WTT1_HUMAN,tr|A0A7I2YQ90|A0A7I2YQ90_HUMAN,tr|A0A7I2V4N4|A0A7I2V4N4_HUMAN,tr|E7EQV3|E7EQV3_HUMAN" 15 978.5486 1.51 41476 4953 2 978.545326 490.2816 Polyadenylate-binding protein 3 OS=Homo sapiens OX=9606 GN=PABPC3 PE=1 SV=2 9.79 1557.3 - 657654 - - - -3.3447 - 2.764 0.143 - 649.4 1 1 0 -0.0033 11 0 0 0 3.15E+07 2.08E+07 - - - 2.8465 0.9804 221125_WJC_METTL3_EV_vs_WT_F04.04957.04957.2 0.00782 14-Sep R.VTDYAEEK[136.11].E "sp|Q9NX55|HYPK_HUMAN,tr|J3QT56|J3QT56_HUMAN" 2 961.4484 0.71 41478 4957 2 961.44246 481.7315 Huntingtin-interacting protein K OS=Homo sapiens OX=9606 GN=HYPK PE=1 SV=2 4.14 1557.8 - 1.16E+06 - - - -6.1699 - 1.714 0.332 - 250.9 1 2 0 -0.0059 8 0 0 0 1.48E+07 2.09E+07 - - - 3.1164 0.9998 221125_WJC_METTL3_EV_vs_WT_F04.04962.04962.2 0.0033 18-Oct R.VVAVSDGETK[136.11].F "sp|Q8IZH2|XRN1_HUMAN,tr|H7C5E4|H7C5E4_HUMAN" 2 1011.5328 1.4 41481 4962 2 1011.532123 506.7737 5'-3' exoribonuclease 1 OS=Homo sapiens OX=9606 GN=XRN1 PE=1 SV=1 4.37 1558.3 - 1.17E+06 - - - -0.6594 - 1.987 0.398 - 333.4 1 2 0 -0.0007 10 0 0 0 1.40E+08 9.99E+07 - - - 3.897 0.9933 221125_WJC_METTL3_EV_vs_WT_F04.04968.04968.2 0.074 14-Jul R.VTDYAEEK.E "sp|Q9NX55|HYPK_HUMAN,tr|J3QT56|J3QT56_HUMAN" 2 953.4342 0.71 41485 4968 2 953.430802 477.7244 Huntingtin-interacting protein K OS=Homo sapiens OX=9606 GN=HYPK PE=1 SV=2 4.14 1559 - 1.37E+06 - - - -3.5556 - 1.387 0.318 - 132.6 1 2 0 -0.0034 8 0 0 0 1.48E+07 2.09E+07 - - - 2.3753 0.9995 221125_WJC_METTL3_EV_vs_WT_F04.04972.04972.2 0.00227 18-Jul R.VLVNSASAQK.R "sp|O75122|CLAP2_HUMAN,tr|E7ERI8|E7ERI8_HUMAN,tr|A0A804HJG7|A0A804HJG7_HUMAN,tr|J3KR49|J3KR49_HUMAN,tr|E7EW49|E7EW49_HUMAN,tr|E3W994|E3W994_HUMAN,tr|A0A0U1RQI6|A0A0U1RQI6_HUMAN" 7 1015.5662 0.71 41489 4972 2 1015.565785 508.7904 CLIP-associating protein 2 OS=Homo sapiens OX=9606 GN=CLASP2 PE=1 SV=3 8.72 1559.3 - 705414 - - - -0.4175 - 1.547 0.37 - 109.4 1 2 0 -0.0004 10 0 0 0 4.85E+06 6.82E+06 - - - 2.9916 0.9805 221125_WJC_METTL3_EV_vs_WT_F04.04976.04976.2 0.0545 16-Sep R.ALDC[160.03]SSSVR.Q "sp|Q9BTC8|MTA3_HUMAN,sp|Q13330|MTA1_HUMAN,tr|E9PCS8|E9PCS8_HUMAN,tr|H0Y4T7|H0Y4T7_HUMAN,tr|E7EQY4|E7EQY4_HUMAN,tr|E7EV10|E7EV10_HUMAN,tr|F6RRE2|F6RRE2_HUMAN,tr|E7ESY4|E7ESY4_HUMAN" 8 993.4549 2.65 41491 4976 2 993.450106 497.7347 Metastasis-associated protein MTA3 OS=Homo sapiens OX=9606 GN=MTA3 PE=1 SV=2 5.87 1559.8 - 1.96E+06 - - - -4.8699 - 1.297 0.334 - 269.3 1 2 0 -0.0048 9 0 0 0 1.65E+07 6.23E+06 - - - 2.2588 0.9819 221125_WJC_METTL3_EV_vs_WT_F04.04979.04979.2 0.776 12-Jul K.VEYDGER.K sp|P53350|PLK1_HUMAN 1 866.377 0.22 41494 4979 2 866.372833 434.1958 Serine\threonine-protein kinase PLK1 OS=Homo sapiens OX=9606 GN=PLK1 PE=1 SV=1 4.14 1560.1 - 953158 - - - -4.8224 - 1.345 0.314 - 179.8 1 2 0 -0.0042 7 0 0 0 5.77E+06 2.57E+07 - - - 2.298 0.9996 221125_WJC_METTL3_EV_vs_WT_F04.04983.04983.2 0.0736 14-Aug K.TGASVLNK.W "sp|Q92499|DDX1_HUMAN,tr|A0A7I2V2M5|A0A7I2V2M5_HUMAN,tr|A0A7I2V430|A0A7I2V430_HUMAN,tr|A0A7I2V421|A0A7I2V421_HUMAN,tr|A0A7I2V4F0|A0A7I2V4F0_HUMAN,tr|A0A7I2V4Q0|A0A7I2V4Q0_HUMAN,tr|A0A7I2YQD0|A0A7I2YQD0_HUMAN,tr|A0A7I2V5X8|A0A7I2V5X8_HUMAN,tr|A0A7I2V4J3|A0A7I2V4J3_HUMAN,tr|A0A7I2YQ77|A0A7I2YQ77_HUMAN" 10 788.4392 0.09 41496 4983 2 788.438804 395.2269 ATP-dependent RNA helicase DDX1 OS=Homo sapiens OX=9606 GN=DDX1 PE=1 SV=2 8.41 1560.5 - 7.58E+06 - - - -0.5251 - 1.643 0.384 - 252.6 1 2 0 -0.0004 8 0 0 0 3.08E+08 3.42E+09 - - - 3.3746 0.9418 221125_WJC_METTL3_EV_vs_WT_F04.04987.04987.2 0.0708 14-Aug K.AGDAPLVK.V "sp|Q9HC56|PCDH9_HUMAN,tr|Q5VT82|Q5VT82_HUMAN,tr|B7ZM79|B7ZM79_HUMAN" 3 769.4334 22.26 41497 4987 2 769.43036 385.724 Protocadherin-9 OS=Homo sapiens OX=9606 GN=PCDH9 PE=1 SV=2 5.88 1561.1 - 1.15E+07 - - - -3.9562 - 1.636 0.049 - 278.5 1 2 0 -0.003 8 0 0 0 7.09E+08 3.19E+07 - - - 0.8866 0.9983 221125_WJC_METTL3_EV_vs_WT_F04.04990.04990.2 0.00107 16-Sep K.VGQASEIAR[166.11].Q sp|Q99459|CDC5L_HUMAN 1 939.5013 0.29 41498 4990 2 939.497839 470.7579 Cell division cycle 5-like protein OS=Homo sapiens OX=9606 GN=CDC5L PE=1 SV=2 5.97 1561.5 - 7.51E+06 - - - -3.6988 - 1.861 0.415 - 237 1 2 0 -0.0035 9 0 0 0 2.14E+08 7.40E+08 - - - 3.902 0.999 221125_WJC_METTL3_EV_vs_WT_F04.05023.05023.2 0.00735 16-Aug K.FEETTADGR.K "sp|Q01469|FABP5_HUMAN,tr|I6L8B7|I6L8B7_HUMAN" 2 1024.4462 859.51 41504 5023 2 1024.442997 513.2304 Fatty acid-binding protein 5 OS=Homo sapiens OX=9606 GN=FABP5 PE=1 SV=3 4.14 1566.4 - 4.45E+06 - - - -3.0817 - 1.806 0.441 - 188.8 1 2 0 -0.0032 9 0 0 0 1.63E+08 1.89E+05 - - - 4.0074 0.9986 221125_WJC_METTL3_EV_vs_WT_F04.05028.05028.2 2.70E-06 20-Dec K.GGDAPAAGEDA.- sp|P62851|RS25_HUMAN 1 929.3727 - 41506 5028 2 929.368252 465.6936 40S ribosomal protein S25 OS=Homo sapiens OX=9606 GN=RPS25 PE=1 SV=1 3.49 1567 - 8.52E+06 - - - -4.7365 - 2.143 0.592 - 526.8 1 2 0 -0.0044 11 0 0 0 - - - - - 5.4741 0.9996 221125_WJC_METTL3_EV_vs_WT_F04.05036.05036.2 0.00208 14-Oct R.MLQADPNK.V sp|Q9Y3I0|RTCB_HUMAN 1 915.4484 0.74 41508 5036 2 915.447987 458.7315 RNA-splicing ligase RtcB homolog OS=Homo sapiens OX=9606 GN=RTCB PE=1 SV=1 5.59 1568.1 - 8.21E+06 - - - -0.4533 - 1.553 0.4 - 267.2 1 2 0 -0.0004 8 0 0 0 1.84E+08 2.50E+08 - - - 3.3229 0.7821 221125_WJC_METTL3_EV_vs_WT_F04.05037.05037.2 2.50E-05 16-Oct S.SVLAGGSC[160.03]R.A "sp|P02533|K1C14_HUMAN,sp|P08779|K1C16_HUMAN,tr|K7ENV3|K7ENV3_HUMAN" 3 905.4389 9.39 41509 5037 2 905.433717 453.7267 "Keratin, type I cytoskeletal 14 OS=Homo sapiens OX=9606 GN=KRT14 PE=1 SV=4" 7.96 1568.2 - 6.73E+06 - - - -5.7243 - 1.958 0.484 - 382.5 1 1 0 -0.0052 9 0 0 0 1.76E+09 1.88E+08 - - - 4.5581 0.9901 221125_WJC_METTL3_EV_vs_WT_F04.05040.05040.2 0.0279 12-Jun R.EVIC[160.03]TSR.D "sp|Q9Y4Z0|LSM4_HUMAN,tr|U3KQK1|U3KQK1_HUMAN,tr|M0QXB0|M0QXB0_HUMAN,tr|V9GZ56|V9GZ56_HUMAN" 4 863.4171 0.79 41510 5040 2 863.41963 432.7158 U6 snRNA-associated Sm-like protein LSm4 OS=Homo sapiens OX=9606 GN=LSM4 PE=1 SV=1 6.09 1568.6 - 5.11E+06 - - - 2.9279 - 1.296 0.247 - 176 1 2 0 0.0025 7 0 0 0 2.23E+08 2.81E+08 - - - 1.6861 0.9984 221125_WJC_METTL3_EV_vs_WT_F04.05046.05046.2 0.0018 16-Sep K.TIAPQNAPR.D "sp|Q9NYF8|BCLF1_HUMAN,tr|H0YF00|H0YF00_HUMAN,tr|E9PKI6|E9PKI6_HUMAN,tr|A0A1W2PQ43|A0A1W2PQ43_HUMAN,tr|E9PK91|E9PK91_HUMAN,tr|E9PJA7|E9PJA7_HUMAN,tr|E9PK09|E9PK09_HUMAN,tr|E9PQN2|E9PQN2_HUMAN" 8 966.5247 2.29 41512 5046 2 966.521763 484.2696 Bcl-2-associated transcription factor 1 OS=Homo sapiens OX=9606 GN=BCLAF1 PE=1 SV=2 9.41 1569.4 - 2.66E+06 - - - -3.017 - 1.676 0.386 - 244.8 1 2 0 -0.0029 9 0 0 0 7.93E+08 3.46E+08 - - - 3.3851 0.9773 221125_WJC_METTL3_EV_vs_WT_F04.05051.05051.2 2.07 14-Aug R.LAQIQQAK.K "sp|Q9NUL3|STAU2_HUMAN,sp|O95793|STAU1_HUMAN,tr|E5RJN7|E5RJN7_HUMAN,tr|Q5JW30|Q5JW30_HUMAN,tr|E7EVJ4|E7EVJ4_HUMAN,tr|E7EVI1|E7EVI1_HUMAN,tr|E7EPX0|E7EPX0_HUMAN" 7 898.5236 1.91 41513 5051 2 898.519329 450.2691 Double-stranded RNA-binding protein Staufen homolog 2 OS=Homo sapiens OX=9606 GN=STAU2 PE=1 SV=2 8.75 1570.1 - 6.59E+06 - - - -4.7712 - 1.708 0.192 - 187.6 1 2 0 -0.0043 8 0 0 0 9.90E+08 5.19E+08 - - - 2.0723 0.9941 221125_WJC_METTL3_EV_vs_WT_F04.05055.05055.2 0.081 14-Oct K.MGGDIANR[166.11].V "sp|Q9UQ80|PA2G4_HUMAN,tr|F8VR77|F8VR77_HUMAN" 2 842.3944 0.45 41515 5055 2 842.390353 422.2045 Proliferation-associated protein 2G4 OS=Homo sapiens OX=9606 GN=PA2G4 PE=1 SV=3 5.59 1570.7 - 4.82E+06 - - - -4.8113 - 1.81 0.348 - 331.3 1 2 0 -0.0041 8 0 0 0 7.52E+07 1.68E+08 - - - 3.3995 0.9873 221125_WJC_METTL3_EV_vs_WT_F04.05056.05056.2 0.0381 14-Jul K.QQLVTTAK.R "sp|P42694|HELZ_HUMAN,tr|J3QRR8|J3QRR8_HUMAN,tr|J3QS41|J3QS41_HUMAN,tr|A0A075B6R3|A0A075B6R3_HUMAN" 4 887.5076 2.29 41516 5056 2 887.503771 444.7611 Probable helicase with zinc finger domain OS=Homo sapiens OX=9606 GN=HELZ PE=1 SV=2 8.75 1570.7 - 5.25E+06 - - - -4.3504 - 1.475 0.285 - 243.7 1 2 0 -0.0039 8 0 0 0 1.14E+08 4.96E+07 - - - 2.317 0.9983 221125_WJC_METTL3_EV_vs_WT_F04.05057.05057.2 0.181 12-Aug R.K[136.11]IFVGTK[136.11].G sp|P62701|RS4X_HUMAN 1 807.5189 0.93 41517 5057 2 807.518761 404.7667 "40S ribosomal protein S4, X isoform OS=Homo sapiens OX=9606 GN=RPS4X PE=1 SV=2" 10 1570.8 - 4.24E+06 - - - -0.2031 - 1.523 0.209 - 277.7 1 2 0 -0.0002 7 0 0 0 2.80E+08 3.00E+08 - - - 1.9176 0.9905 221125_WJC_METTL3_EV_vs_WT_F04.05058.05058.2 0.27 16-Sep K.YEAAGEAVK.T sp|O15226|NKRF_HUMAN 1 936.4553 0.68 41518 5058 2 936.452026 469.2349 NF-kappa-B-repressing factor OS=Homo sapiens OX=9606 GN=NKRF PE=1 SV=2 4.53 1570.9 - 1.55E+06 - - - -3.4556 - 1.446 0.257 - 205.9 1 2 0 -0.0032 9 0 0 0 6.32E+07 9.31E+07 - - - 2.0051 0.9972 221125_WJC_METTL3_EV_vs_WT_F04.05070.05070.2 0.0814 12-Jun R.ENPVYEK.K "sp|P46777|RL5_HUMAN,tr|A0A2R8Y6J3|A0A2R8Y6J3_HUMAN,tr|A0A2R8Y4A2|A0A2R8Y4A2_HUMAN" 3 877.4181 0.66 41523 5070 2 877.418233 439.7164 60S ribosomal protein L5 OS=Homo sapiens OX=9606 GN=RPL5 PE=1 SV=3 4.53 1572.4 - 3.64E+06 - - - 0.0969 - 1.285 0.228 - 227.5 1 2 0 0.0001 7 0 0 0 3.08E+08 4.68E+08 - - - 1.5195 0.9951 221125_WJC_METTL3_EV_vs_WT_F04.05072.05072.2 0.325 12-Jun R.LQATEVR[166.11].L sp|Q9UI30|TR112_HUMAN 1 825.4584 0.22 41525 5072 2 825.457201 413.7365 Multifunctional methyltransferase subunit TRM112-like protein OS=Homo sapiens OX=9606 GN=TRMT112 PE=1 SV=1 6 1572.5 - 3.58E+06 - - - -1.4368 - 1.419 0.17 - 74.7 1 2 0 -0.0012 7 0 0 0 4.14E+07 1.85E+08 - - - 1.4051 0.9884 221125_WJC_METTL3_EV_vs_WT_F04.05073.05073.2 1.11E-05 16-Dec K.PADAVYGQK.E "sp|Q13283|G3BP1_HUMAN,tr|A0A7I2V5M7|A0A7I2V5M7_HUMAN,tr|E5RH42|E5RH42_HUMAN,tr|A0A7P0P2U7|A0A7P0P2U7_HUMAN,tr|A0A7I2V2S5|A0A7I2V2S5_HUMAN,tr|A0A7I2YQU8|A0A7I2YQU8_HUMAN,tr|E5RJU8|E5RJU8_HUMAN,tr|A0A7I2V651|A0A7I2V651_HUMAN,tr|E5RIF8|E5RIF8_HUMAN,tr|A0A7I2YQN9|A0A7I2YQN9_HUMAN" 10 947.4712 1.28 41526 5073 2 947.469243 474.7429 Ras GTPase-activating protein-binding protein 1 OS=Homo sapiens OX=9606 GN=G3BP1 PE=1 SV=1 6.26 1572.6 - 3.19E+06 - - - -2.114 - 2.287 0.572 - 452.4 1 1 0 -0.002 9 0 0 0 8.05E+07 6.30E+07 - - - 5.6584 0.9898 221125_WJC_METTL3_EV_vs_WT_F04.05074.05074.2 0.0647 16-Nov K.PADAVYGQK[136.11].E "sp|Q13283|G3BP1_HUMAN,tr|A0A7I2V5M7|A0A7I2V5M7_HUMAN,tr|E5RH42|E5RH42_HUMAN,tr|A0A7P0P2U7|A0A7P0P2U7_HUMAN,tr|A0A7I2V2S5|A0A7I2V2S5_HUMAN,tr|A0A7I2YQU8|A0A7I2YQU8_HUMAN,tr|E5RJU8|E5RJU8_HUMAN,tr|A0A7I2V651|A0A7I2V651_HUMAN,tr|E5RIF8|E5RIF8_HUMAN,tr|A0A7I2YQN9|A0A7I2YQN9_HUMAN" 10 955.4854 1.28 41527 5074 2 955.485028 478.75 Ras GTPase-activating protein-binding protein 1 OS=Homo sapiens OX=9606 GN=G3BP1 PE=1 SV=1 6.26 1572.7 - 1.67E+06 - - - -0.4375 - 2.29 0.39 - 354.1 1 1 0 -0.0004 9 0 0 0 8.05E+07 6.30E+07 - - - 4.3185 0.9996 221125_WJC_METTL3_EV_vs_WT_F04.05076.05076.2 0.00144 16-Sep K.EGVVAAAEK.T "sp|Q16143|SYUB_HUMAN,sp|P37840|SYUA_HUMAN,tr|A0A669KB41|A0A669KB41_HUMAN,tr|G4Y816|G4Y816_HUMAN,tr|D6RA31|D6RA31_HUMAN,tr|A0A669KBH5|A0A669KBH5_HUMAN,tr|H6UYS7|H6UYS7_HUMAN,tr|E7EPV7|E7EPV7_HUMAN" 8 872.4603 1.63 41528 5076 2 872.458328 437.2374 Beta-synuclein OS=Homo sapiens OX=9606 GN=SNCB PE=1 SV=1 4.53 1572.9 - 4.26E+07 - - - -2.3141 - 2.043 0.452 - 281.3 1 2 0 -0.002 9 0 0 0 3.58E+09 2.20E+09 - - - 4.4457 0.98 221125_WJC_METTL3_EV_vs_WT_F04.05080.05080.2 2.34 12-Jun K.VSSFEEK.M "sp|P40926|MDHM_HUMAN,tr|G3XAL0|G3XAL0_HUMAN" 2 824.3916 107.33 41531 5080 2 824.390736 413.2031 "Malate dehydrogenase, mitochondrial OS=Homo sapiens OX=9606 GN=MDH2 PE=1 SV=3" 4.53 1573.3 - 3.76E+06 - - - -1.0468 - 1.182 0.097 - 82.4 1 2 0 -0.0009 7 0 0 0 1.00E+08 9.36E+05 - - - 0.287 0.9944 221125_WJC_METTL3_EV_vs_WT_F04.05088.05088.2 0.697 12-Jul R.KIFVGTK.G sp|P62701|RS4X_HUMAN 1 791.4905 0.93 41536 5088 2 791.489805 396.7525 "40S ribosomal protein S4, X isoform OS=Homo sapiens OX=9606 GN=RPS4X PE=1 SV=2" 10 1574.1 - 5.44E+06 - - - -0.9097 - 1.584 0.085 - 209.3 1 2 0 -0.0007 7 0 0 0 2.80E+08 3.00E+08 - - - 1.126 0.9967 221125_WJC_METTL3_EV_vs_WT_F04.05098.05098.2 0.0157 16-Sep K.TIAPQNAPR[166.11].D "sp|Q9NYF8|BCLF1_HUMAN,tr|H0YF00|H0YF00_HUMAN,tr|E9PKI6|E9PKI6_HUMAN,tr|A0A1W2PQ43|A0A1W2PQ43_HUMAN,tr|E9PK91|E9PK91_HUMAN,tr|E9PJA7|E9PJA7_HUMAN,tr|E9PK09|E9PK09_HUMAN,tr|E9PQN2|E9PQN2_HUMAN" 8 976.5329 2.29 41541 5098 2 976.531575 489.2738 Bcl-2-associated transcription factor 1 OS=Homo sapiens OX=9606 GN=BCLAF1 PE=1 SV=2 9.41 1575.2 - 6.30E+06 - - - -1.407 - 1.55 0.188 - 217.3 1 2 0 -0.0014 9 0 0 0 7.93E+08 3.46E+08 - - - 1.697 0.897 221125_WJC_METTL3_EV_vs_WT_F04.05114.05114.2 4.66 14-Jun K.LTVENSPK.Q "sp|O43583|DENR_HUMAN,tr|F8VVL1|F8VVL1_HUMAN" 2 886.476 0.36 41547 5114 2 886.475837 444.2453 Density-regulated protein OS=Homo sapiens OX=9606 GN=DENR PE=1 SV=2 6 1577.3 - 6.25E+06 - - - -0.1805 - 1.075 0.018 - 113.8 5 2 0 -0.0002 8 0 0 0 7.08E+07 1.96E+08 - - - -0.9202 0.9983 221125_WJC_METTL3_EV_vs_WT_F04.05124.05124.2 0.0449 12-Jun R.ENPVYEK[136.11].K "sp|P46777|RL5_HUMAN,tr|A0A2R8Y6J3|A0A2R8Y6J3_HUMAN,tr|A0A2R8Y4A2|A0A2R8Y4A2_HUMAN" 3 885.4323 0.66 41549 5124 2 885.431787 443.7235 60S ribosomal protein L5 OS=Homo sapiens OX=9606 GN=RPL5 PE=1 SV=3 4.53 1578.8 - 5.42E+06 - - - -0.6336 - 1.309 0.279 - 244.1 1 2 0 -0.0006 7 0 0 0 3.08E+08 4.68E+08 - - - 1.9547 0.9868 221125_WJC_METTL3_EV_vs_WT_F04.05130.05130.2 5.38 14-Sep R.LAQIQQAK[136.11].K "sp|Q9NUL3|STAU2_HUMAN,sp|O95793|STAU1_HUMAN,tr|E5RJN7|E5RJN7_HUMAN,tr|Q5JW30|Q5JW30_HUMAN,tr|E7EVJ4|E7EVJ4_HUMAN,tr|E7EVI1|E7EVI1_HUMAN,tr|E7EPX0|E7EPX0_HUMAN" 7 906.5378 1.91 41552 5130 2 906.537078 454.2762 Double-stranded RNA-binding protein Staufen homolog 2 OS=Homo sapiens OX=9606 GN=STAU2 PE=1 SV=2 8.75 1579.6 - 3.56E+06 - - - -0.8141 - 1.221 0.117 - 212.7 1 2 0 -0.0007 8 0 0 0 9.90E+08 5.19E+08 - - - 0.5071 0.9971 221125_WJC_METTL3_EV_vs_WT_F04.05131.05131.2 0.278 14-Jul R.TQEEIVAK[136.11].V "sp|P13667|PDIA4_HUMAN,tr|A0A499FI48|A0A499FI48_HUMAN" 2 924.5008 0.66 41553 5131 2 924.501002 463.2577 Protein disulfide-isomerase A4 OS=Homo sapiens OX=9606 GN=PDIA4 PE=1 SV=2 4.53 1579.7 - 1.05E+06 - - - 0.2596 - 1.577 0.15 - 219.9 1 2 0 0.0002 8 0 0 0 2.76E+07 4.20E+07 - - - 1.5227 0.9928 221125_WJC_METTL3_EV_vs_WT_F04.05135.05135.2 0.00349 14-Sep K.QSVVYGGK.S "sp|Q8WWY3|PRP31_HUMAN,tr|E7EVX8|E7EVX8_HUMAN" 2 836.4392 2.68 41555 5135 2 836.438054 419.2269 U4\U6 small nuclear ribonucleoprotein Prp31 OS=Homo sapiens OX=9606 GN=PRPF31 PE=1 SV=2 8.59 1580.2 - 1.26E+06 - - - -1.3916 - 1.732 0.055 - 372.7 1 2 0 -0.0012 8 0 0 0 4.83E+08 1.80E+08 - - - 1.1035 0.9995 221125_WJC_METTL3_EV_vs_WT_F04.05152.05152.2 0.00103 16-Aug K.EGVVAAAEK[136.11].T "sp|Q16143|SYUB_HUMAN,sp|P37840|SYUA_HUMAN,tr|A0A669KB41|A0A669KB41_HUMAN,tr|G4Y816|G4Y816_HUMAN,tr|D6RA31|D6RA31_HUMAN,tr|A0A669KBH5|A0A669KBH5_HUMAN,tr|H6UYS7|H6UYS7_HUMAN,tr|E7EPV7|E7EPV7_HUMAN" 8 880.4745 1.63 41561 5152 2 880.474574 441.2445 Beta-synuclein OS=Homo sapiens OX=9606 GN=SNCB PE=1 SV=1 4.53 1582.6 - 8.22E+06 - - - 0.0307 - 1.808 0.318 - 214 1 2 0 0 9 0 0 0 3.58E+09 2.20E+09 - - - 3.1031 0.9988 221125_WJC_METTL3_EV_vs_WT_F04.05154.05154.2 0.027 12-Jun R.QQEEMMR[166.11].R "sp|Q15233|NONO_HUMAN,tr|A0A7I2V535|A0A7I2V535_HUMAN,tr|A0A7I2V4K9|A0A7I2V4K9_HUMAN,tr|A0A7P0MRW0|A0A7P0MRW0_HUMAN,tr|H7C367|H7C367_HUMAN,tr|A0A7I2V4J2|A0A7I2V4J2_HUMAN,tr|A0A7I2V5Y7|A0A7I2V5Y7_HUMAN" 7 960.4033 0.75 41563 5154 2 960.40424 481.2089 Non-POU domain-containing octamer-binding protein OS=Homo sapiens OX=9606 GN=NONO PE=1 SV=4 4.53 1582.8 - 504878 - - - 1.0246 - 1.313 0.346 - 217.1 1 2 0 0.001 7 0 0 0 3.86E+07 5.15E+07 - - - 2.4591 0.9996 221125_WJC_METTL3_EV_vs_WT_F04.05166.05166.2 0.000466 18-Jul K.EPAAAPDSVR.K sp|Q9Y6J9|TAF6L_HUMAN 1 1011.4985 1.15 41569 5166 2 1011.498584 506.7565 TAF6-like RNA polymerase II p300\CBP-associated factor-associated factor 65 kDa subunit 6L OS=Homo sapiens OX=9606 GN=TAF6L PE=1 SV=1 4.37 1584.3 - 337424 - - - 0.0603 - 1.517 0.423 - 207 1 2 0 0.0001 10 0 0 0 3.38E+07 2.93E+07 - - - 3.3285 0.9747 221125_WJC_METTL3_EV_vs_WT_F04.05172.05172.2 0.0244 14-Aug K.QSVVYGGK[136.11].S "sp|Q8WWY3|PRP31_HUMAN,tr|E7EVX8|E7EVX8_HUMAN" 2 844.4534 2.7 41572 5172 2 844.454827 423.234 U4\U6 small nuclear ribonucleoprotein Prp31 OS=Homo sapiens OX=9606 GN=PRPF31 PE=1 SV=2 8.59 1585 - 3.95E+06 - - - 1.6685 - 1.379 0.055 - 323.5 1 2 0 0.0014 8 0 0 0 4.81E+08 1.78E+08 - - - 0.416 0.9947 221125_WJC_METTL3_EV_vs_WT_F04.05173.05173.2 0.237 14-Sep K.LTVENSPK[136.11].Q "sp|O43583|DENR_HUMAN,tr|F8VVL1|F8VVL1_HUMAN" 2 894.4902 0.36 41573 5173 2 894.48835 448.2524 Density-regulated protein OS=Homo sapiens OX=9606 GN=DENR PE=1 SV=2 6 1585.1 - 374520 - - - -2.0649 - 1.378 0.224 - 167.1 1 2 0 -0.0018 8 0 0 0 7.08E+07 1.96E+08 - - - 1.6619 0.9994 221125_WJC_METTL3_EV_vs_WT_F04.05176.05176.2 0.000645 14-Aug R.LLTGDC[160.03]QK[136.11].N "sp|Q9BQ67|GRWD1_HUMAN,tr|M0QX71|M0QX71_HUMAN" 2 941.4732 0.47 41576 5176 2 941.472948 471.7439 Glutamate-rich WD repeat-containing protein 1 OS=Homo sapiens OX=9606 GN=GRWD1 PE=1 SV=1 5.83 1585.4 - 349317 - - - -0.2326 - 1.277 0.408 - 150 1 2 0 -0.0002 8 0 0 0 5.30E+07 1.12E+08 - - - 2.7919 0.8443 221125_WJC_METTL3_EV_vs_WT_F04.05178.05178.2 6.24 18-Apr K.IESGEMGLNK.V "sp|O75071|EFC14_HUMAN,tr|A0A6I8PU78|A0A6I8PU78_HUMAN,tr|A0A6I8PIP2|A0A6I8PIP2_HUMAN,tr|A0A804H3B5|A0A804H3B5_HUMAN,tr|A0A6I8PIF8|A0A6I8PIF8_HUMAN" 5 1076.5172 3.53 41577 5178 2 1076.517423 539.2659 EF-hand calcium-binding domain-containing protein 14 OS=Homo sapiens OX=9606 GN=EFCAB14 PE=1 SV=1 4.53 1585.7 - 1.08E+06 - - - 0.1979 - 1.019 0.038 - 35.1 19 2 0 0.0002 10 0 0 0 1.14E+08 3.23E+07 - - - -1.1971 0.9917 221125_WJC_METTL3_EV_vs_WT_F04.05182.05182.2 0.0289 18-Jul K.EPAAAPDSVR[166.11].K sp|Q9Y6J9|TAF6L_HUMAN 1 1021.5068 1.26 41580 5182 2 1021.511042 511.7607 TAF6-like RNA polymerase II p300\CBP-associated factor-associated factor 65 kDa subunit 6L OS=Homo sapiens OX=9606 GN=TAF6L PE=1 SV=1 4.37 1586.2 - 259026 - - - 4.1595 - 1.609 0.302 - 216.1 1 2 0 0.0042 10 0 0 0 1.10E+07 8.70E+06 - - - 2.5978 0.8064 221125_WJC_METTL3_EV_vs_WT_F04.05196.05196.2 2.06 12-Sep S.K[136.11]IDEVLK[136.11].Y sp|Q8WWZ8|OIT3_HUMAN 1 859.535 1.68 41587 5196 2 859.535338 430.7748 Oncoprotein-induced transcript 3 protein OS=Homo sapiens OX=9606 GN=OIT3 PE=1 SV=2 6.07 1588 - 1.79E+06 - - - 0.4293 - 2.051 0 - 351.4 1 1 0 0.0004 7 0 0 0 1.63E+08 9.73E+07 - - - 1.3169 0.9998 221125_WJC_METTL3_EV_vs_WT_F04.05202.05202.2 0.006 18-Nov K.LAESGSSLGK[136.11].K "sp|Q8NFF5|FAD1_HUMAN,tr|Q5T196|Q5T196_HUMAN" 2 955.5066 0.67 41591 5202 2 955.506473 478.7606 FAD synthase OS=Homo sapiens OX=9606 GN=FLAD1 PE=1 SV=1 6 1588.8 - 505757 - - - -0.1067 - 2.341 0.393 - 273.4 1 2 0 -0.0001 10 0 0 0 1.69E+07 2.52E+07 - - - 4.3179 0.999 221125_WJC_METTL3_EV_vs_WT_F04.05214.05214.2 0.114 14-Jul R.LSDSPSMK[136.11].K "sp|Q9BY77|PDIP3_HUMAN,tr|F6VRR5|F6VRR5_HUMAN" 2 871.4201 1.54 41597 5214 2 871.421489 436.7173 Polymerase delta-interacting protein 3 OS=Homo sapiens OX=9606 GN=POLDIP3 PE=1 SV=2 5.84 1590.4 - 1.48E+06 - - - 1.6295 - 1.524 0.357 - 124 1 2 0 0.0014 8 0 0 0 8.84E+08 5.75E+08 - - - 2.9481 0.9979 221125_WJC_METTL3_EV_vs_WT_F04.05215.05215.2 0.426 14-Jul K.VVLTQANK[136.11].L "sp|O94979|SC31A_HUMAN,tr|H0YAF5|H0YAF5_HUMAN,tr|H0Y8W8|H0Y8W8_HUMAN,tr|H7BXG7|H7BXG7_HUMAN,tr|D6REX3|D6REX3_HUMAN" 5 879.5269 1.11 41598 5215 2 879.52743 440.7707 Protein transport protein Sec31A OS=Homo sapiens OX=9606 GN=SEC31A PE=1 SV=3 8.72 1590.5 - 988449 - - - 0.5833 - 1.166 0.317 - 121.3 1 2 0 0.0005 8 0 0 0 4.67E+07 4.21E+07 - - - 1.8454 0.9998 221125_WJC_METTL3_EV_vs_WT_F04.05216.05216.2 4.32E-05 14-Aug K.VFTASC[160.03]DK.T "sp|P78406|RAE1L_HUMAN,tr|B0QZ36|B0QZ36_HUMAN,tr|E9PQ57|E9PQ57_HUMAN,tr|E9PPG9|E9PPG9_HUMAN" 4 926.4168 1.71 41599 5216 2 926.417952 464.2157 mRNA export factor OS=Homo sapiens OX=9606 GN=RAE1 PE=1 SV=1 5.8 1590.5 - 9.01E+06 - - - 1.278 - 1.653 0.554 - 221.6 1 2 0 0.0012 8 0 0 0 5.92E+08 3.47E+08 - - - 4.6483 0.9999 221125_WJC_METTL3_EV_vs_WT_F04.05217.05217.2 2.32E-05 14-Sep K.VFTASC[160.03]DK[136.11].T "sp|P78406|RAE1L_HUMAN,tr|B0QZ36|B0QZ36_HUMAN,tr|E9PQ57|E9PQ57_HUMAN,tr|E9PPG9|E9PPG9_HUMAN" 4 934.431 1.71 41600 5217 2 934.431131 468.2228 mRNA export factor OS=Homo sapiens OX=9606 GN=RAE1 PE=1 SV=1 5.8 1590.6 - 6.11E+06 - - - 0.1744 - 1.762 0.529 - 280.4 1 2 0 0.0002 8 0 0 0 5.92E+08 3.47E+08 - - - 4.6565 0.9913 221125_WJC_METTL3_EV_vs_WT_F04.05225.05225.2 0.463 16-Jul K.IIEGGAAQK.D "sp|Q92796|DLG3_HUMAN,tr|Q5JUW8|Q5JUW8_HUMAN" 2 885.492 437.07 41603 5225 2 885.492843 443.7533 Disks large homolog 3 OS=Homo sapiens OX=9606 GN=DLG3 PE=1 SV=2 6 1591.7 - 941515 - - - 0.9723 - 1.225 0.172 - 100.6 1 2 0 0.0009 9 0 0 0 7.36E+07 1.68E+05 - - - 0.8982 0.9998 221125_WJC_METTL3_EV_vs_WT_F04.05227.05227.2 0.0543 18-Oct R.APGAGLGQDR[166.11].Q "sp|P50402|EMD_HUMAN,tr|Q5HY57|Q5HY57_HUMAN" 2 950.4809 1.89 41605 5227 2 950.481633 476.2477 Emerin OS=Homo sapiens OX=9606 GN=EMD PE=1 SV=1 5.88 1591.9 - 919365 - - - 0.7575 - 1.996 0.415 - 359.4 1 2 0 0.0007 10 0 0 0 1.21E+08 6.40E+07 - - - 4.0352 0.9995 221125_WJC_METTL3_EV_vs_WT_F04.05233.05233.2 0.000216 18-Sep K.IAPAEAPDAK.V sp|O00425|IF2B3_HUMAN 1 981.5131 1.74 41609 5233 2 981.514473 491.7638 Insulin-like growth factor 2 mRNA-binding protein 3 OS=Homo sapiens OX=9606 GN=IGF2BP3 PE=1 SV=2 4.37 1592.6 - 1.81E+06 - - - 1.3877 - 1.707 0.406 - 329.1 1 2 0 0.0014 10 0 0 0 3.91E+08 2.25E+08 - - - 3.5319 0.9995 221125_WJC_METTL3_EV_vs_WT_F04.05234.05234.2 0.00338 18-Sep K.IAPAEAPDAK[136.11].V sp|O00425|IF2B3_HUMAN 1 989.5273 1.77 41610 5234 2 989.528685 495.7709 Insulin-like growth factor 2 mRNA-binding protein 3 OS=Homo sapiens OX=9606 GN=IGF2BP3 PE=1 SV=2 4.37 1592.8 - 1.17E+06 - - - 1.3885 - 1.69 0.425 - 336.7 1 2 0 0.0014 10 0 0 0 3.91E+08 2.21E+08 - - - 3.6443 0.9824 221125_WJC_METTL3_EV_vs_WT_F04.05255.05255.2 0.204 12-Jul K.NVDENIR.K "sp|Q9H307|PININ_HUMAN,tr|G3V5F0|G3V5F0_HUMAN,tr|G3V579|G3V579_HUMAN" 3 858.4195 1.85 41616 5255 2 858.42194 430.217 Pinin OS=Homo sapiens OX=9606 GN=PNN PE=1 SV=5 4.37 1595.9 - 1.12E+06 - - - 2.79 - 1.141 0.233 - 210.3 1 2 0 0.0024 7 0 0 0 5.34E+08 2.89E+08 - - - 1.1791 0.9946 221125_WJC_METTL3_EV_vs_WT_F04.05266.05266.2 0.129 12-Jun K.NAEEFTK.K "sp|A0A1B0GUS4|UB2L5_HUMAN,sp|P68036|UB2L3_HUMAN" 2 837.3868 0.75 41620 5266 2 837.387698 419.7007 Ubiquitin-conjugating enzyme E2 L5 OS=Homo sapiens OX=9606 GN=UBE2L5 PE=2 SV=1 4.53 1597.4 - 1.15E+06 - - - 1.0151 - 1.158 0.237 - 176.1 1 2 0 0.0009 7 0 0 0 4.76E+07 6.33E+07 - - - 1.256 0.9912 221125_WJC_METTL3_EV_vs_WT_F04.05268.05268.2 1.7 12-Aug R.LQQQELR.E "sp|O00139|KIF2A_HUMAN,tr|D6R9M0|D6R9M0_HUMAN,tr|A0A6Q8PFA6|A0A6Q8PFA6_HUMAN,tr|A0A6Q8PGG1|A0A6Q8PGG1_HUMAN,tr|A0A6Q8PGH7|A0A6Q8PGH7_HUMAN,tr|A0A669KBE9|A0A669KBE9_HUMAN,tr|A0A6Q8PG37|A0A6Q8PG37_HUMAN,tr|A0A6Q8PH57|A0A6Q8PH57_HUMAN" 8 913.4981 0.66 41621 5268 2 913.499263 457.7563 Kinesin-like protein KIF2A OS=Homo sapiens OX=9606 GN=KIF2A PE=1 SV=3 6 1597.6 - 905580 - - - 1.2403 - 1.544 0.076 - 318.5 1 2 0 0.0011 7 0 0 0 5.47E+07 8.34E+07 - - - 0.9783 0.9997 221125_WJC_METTL3_EV_vs_WT_F04.05277.05277.2 0.0645 14-Aug R.LSDSPSMK.K "sp|Q9BY77|PDIP3_HUMAN,tr|F6VRR5|F6VRR5_HUMAN" 2 863.4059 1.41 41625 5277 2 863.406518 432.7102 Polymerase delta-interacting protein 3 OS=Homo sapiens OX=9606 GN=POLDIP3 PE=1 SV=2 5.84 1598.7 - 8.03E+06 - - - 0.7517 - 1.766 0.42 - 159.2 1 2 0 0.0006 8 0 0 0 7.89E+08 5.61E+08 - - - 3.8581 0.9978 221125_WJC_METTL3_EV_vs_WT_F04.05279.05279.2 0.046 16-Aug K.IEVNNATAR[166.11].V "sp|O43251|RFOX2_HUMAN,sp|Q9NWB1|RFOX1_HUMAN,sp|A6NFN3|RFOX3_HUMAN,tr|A0A6Q8PGE0|A0A6Q8PGE0_HUMAN,tr|A0A6Q8PH77|A0A6Q8PH77_HUMAN,tr|A0A286YEU2|A0A286YEU2_HUMAN,tr|A0A087X2B1|A0A087X2B1_HUMAN,tr|F8VR27|F8VR27_HUMAN,tr|B7Z1U7|B7Z1U7_HUMAN,tr|B0QYV1|B0QYV1_HUMAN,tr|A0A6Q8PHA3|A0A6Q8PHA3_HUMAN,tr|A0A3B3ITL7|A0A3B3ITL7_HUMAN,tr|F8VZY7|F8VZY7_HUMAN,tr|B0QYY4|B0QYY4_HUMAN,tr|J3KNW3|J3KNW3_HUMAN,tr|F8VZG9|F8VZG9_HUMAN,tr|J3QRF4|J3QRF4_HUMAN,tr|F8VRS4|F8VRS4_HUMAN,tr|A0A6Q8PFM4|A0A6Q8PFM4_HUMAN,tr|S4R469|S4R469_HUMAN,tr|A0A804HKG7|A0A804HKG7_HUMAN,tr|A0A0G2JRD1|A0A0G2JRD1_HUMAN,tr|A0A0G2JRA5|A0A0G2JRA5_HUMAN,tr|A0A804HJM2|A0A804HJM2_HUMAN,tr|I3L1D4|I3L1D4_HUMAN,tr|S4R3K7|S4R3K7_HUMAN" 26 996.5228 1.3 41626 5279 2 996.519594 499.2687 RNA binding protein fox-1 homolog 2 OS=Homo sapiens OX=9606 GN=RBFOX2 PE=1 SV=3 6 1599 - 571198 - - - -3.1951 - 1.707 0.353 - 215.7 1 2 0 -0.0032 9 0 0 0 6.38E+08 4.91E+08 - - - 3.1943 0.9888 221125_WJC_METTL3_EV_vs_WT_F04.05288.05288.2 0.222 14-Aug R.QLQQGLAK.C "sp|Q9Y4A5|TRRAP_HUMAN,tr|A0A2R8YFJ4|A0A2R8YFJ4_HUMAN,tr|H0Y4W2|H0Y4W2_HUMAN,tr|F2Z2U4|F2Z2U4_HUMAN" 4 884.508 0.95 41627 5288 2 884.510151 443.2613 Transformation\transcription domain-associated protein OS=Homo sapiens OX=9606 GN=TRRAP PE=1 SV=3 8.75 1600.5 - 297209 - - - 2.4703 - 1.335 0.195 - 186.4 1 2 0 0.0022 8 0 0 0 2.07E+07 2.17E+07 - - - 1.352 0.9816 221125_WJC_METTL3_EV_vs_WT_F04.05299.05299.2 0.339 12-Jun K.EIPETTR.T sp|O43172|PRP4_HUMAN 1 844.429 3.14 41633 5299 2 844.42779 423.2218 U4\U6 small nuclear ribonucleoprotein Prp4 OS=Homo sapiens OX=9606 GN=PRPF4 PE=1 SV=2 4.53 1601.8 - 1.65E+06 - - - -1.4886 - 1.007 0.194 - 174.2 1 2 0 -0.0013 7 0 0 0 1.03E+08 3.27E+07 - - - 0.4956 0.9997 221125_WJC_METTL3_EV_vs_WT_F04.05301.05301.2 9.40E-05 16-Aug R.TPSNLAAAR.L "sp|Q86U86|PB1_HUMAN,tr|H0Y5B5|H0Y5B5_HUMAN,tr|E7EVG2|E7EVG2_HUMAN" 3 899.4825 1.29 41634 5301 2 899.482617 450.7485 Protein polybromo-1 OS=Homo sapiens OX=9606 GN=PBRM1 PE=1 SV=1 9.41 1602 - 2.18E+06 - - - 0.1534 - 1.735 0.415 - 267.8 1 2 0 0.0001 9 0 0 0 2.13E+08 1.65E+08 - - - 3.7002 0.9867 221125_WJC_METTL3_EV_vs_WT_F04.05303.05303.2 2.6 12-Jun R.EMEEQMR[166.11].R "sp|P23246|SFPQ_HUMAN,tr|H0Y9K7|H0Y9K7_HUMAN,tr|H0Y9U2|H0Y9U2_HUMAN" 3 961.3873 0.81 41636 5303 2 961.386574 481.7009 "Splicing factor, proline- and glutamine-rich OS=Homo sapiens OX=9606 GN=SFPQ PE=1 SV=2" 4.25 1602.2 - 348989 - - - -0.726 - 1.199 0.117 - 152.2 1 2 0 -0.0007 7 0 0 0 4.49E+07 5.52E+07 - - - 0.48 0.9998 221125_WJC_METTL3_EV_vs_WT_F04.05306.05306.2 0.00208 16-Sep K.IEVNNATAR.V "sp|O43251|RFOX2_HUMAN,sp|Q9NWB1|RFOX1_HUMAN,sp|A6NFN3|RFOX3_HUMAN,tr|A0A6Q8PGE0|A0A6Q8PGE0_HUMAN,tr|A0A6Q8PH77|A0A6Q8PH77_HUMAN,tr|A0A286YEU2|A0A286YEU2_HUMAN,tr|A0A087X2B1|A0A087X2B1_HUMAN,tr|F8VR27|F8VR27_HUMAN,tr|B7Z1U7|B7Z1U7_HUMAN,tr|B0QYV1|B0QYV1_HUMAN,tr|A0A6Q8PHA3|A0A6Q8PHA3_HUMAN,tr|A0A3B3ITL7|A0A3B3ITL7_HUMAN,tr|F8VZY7|F8VZY7_HUMAN,tr|B0QYY4|B0QYY4_HUMAN,tr|J3KNW3|J3KNW3_HUMAN,tr|F8VZG9|F8VZG9_HUMAN,tr|J3QRF4|J3QRF4_HUMAN,tr|F8VRS4|F8VRS4_HUMAN,tr|A0A6Q8PFM4|A0A6Q8PFM4_HUMAN,tr|S4R469|S4R469_HUMAN,tr|A0A804HKG7|A0A804HKG7_HUMAN,tr|A0A0G2JRD1|A0A0G2JRD1_HUMAN,tr|A0A0G2JRA5|A0A0G2JRA5_HUMAN,tr|A0A804HJM2|A0A804HJM2_HUMAN,tr|I3L1D4|I3L1D4_HUMAN,tr|S4R3K7|S4R3K7_HUMAN" 26 986.5145 1.29 41637 5306 2 986.514566 494.2645 RNA binding protein fox-1 homolog 2 OS=Homo sapiens OX=9606 GN=RBFOX2 PE=1 SV=3 6 1602.6 - 4.04E+06 - - - 0.0588 - 1.923 0.419 - 278.5 1 2 0 0.0001 9 0 0 0 6.32E+08 4.90E+08 - - - 4.0274 0.998 221125_WJC_METTL3_EV_vs_WT_F04.05309.05309.2 0.108 14-Aug K.AINVQEEK.L "sp|Q13813|SPTN1_HUMAN,tr|A0A0D9SF54|A0A0D9SF54_HUMAN,tr|A0A0D9SGF6|A0A0D9SGF6_HUMAN" 3 929.4818 1.47 41639 5309 2 929.481064 465.7482 "Spectrin alpha chain, non-erythrocytic 1 OS=Homo sapiens OX=9606 GN=SPTAN1 PE=1 SV=3" 4.53 1602.9 - 574790 - - - -0.8037 - 1.61 0.191 - 215.2 1 2 0 -0.0007 8 0 0 0 7.21E+07 4.92E+07 - - - 1.8878 0.8478 221125_WJC_METTL3_EV_vs_WT_F04.05317.05317.2 4.69 12-May K.SSTLEVK[136.11].D "sp|Q16514|TAF12_HUMAN,tr|A0A804HLG9|A0A804HLG9_HUMAN" 2 770.4265 1.27 41643 5317 2 770.426867 386.2205 Transcription initiation factor TFIID subunit 12 OS=Homo sapiens OX=9606 GN=TAF12 PE=1 SV=1 5.72 1603.8 - 3.28E+06 - - - 0.4322 - 0.892 0.052 - 91 3 2 0 0.0003 7 0 0 0 2.57E+08 2.02E+08 - - - -1.1503 0.9805 221125_WJC_METTL3_EV_vs_WT_F04.05319.05319.2 4.13 14-Jul K.AINVQEEK[136.11].L "sp|Q13813|SPTN1_HUMAN,tr|A0A0D9SF54|A0A0D9SF54_HUMAN,tr|A0A0D9SGF6|A0A0D9SGF6_HUMAN" 3 937.496 1.59 41644 5319 2 937.494929 469.7553 "Spectrin alpha chain, non-erythrocytic 1 OS=Homo sapiens OX=9606 GN=SPTAN1 PE=1 SV=3" 4.53 1604.1 - 709911 - - - -1.1541 - 1.212 0.097 - 145.4 1 2 0 -0.0011 8 0 0 0 7.89E+07 4.97E+07 - - - 0.337 0.9973 221125_WJC_METTL3_EV_vs_WT_F04.05326.05326.2 0.00238 14-Aug K.ISTVVSSK.E "sp|P37108|SRP14_HUMAN,tr|H0YLA2|H0YLA2_HUMAN" 2 819.4702 1.06 41647 5326 2 819.47142 410.7424 Signal recognition particle 14 kDa protein OS=Homo sapiens OX=9606 GN=SRP14 PE=1 SV=2 8.75 1605 - 8.38E+06 - - - 1.5095 - 1.739 0.173 - 179.4 1 2 0 0.0012 8 0 0 0 7.77E+08 7.35E+08 - - - 1.9871 0.9368 221125_WJC_METTL3_EV_vs_WT_F04.05327.05327.2 0.321 16-Jun R.FDSDAASPR[166.11].E "sp|P01889|HLAB_HUMAN,sp|P10321|HLAC_HUMAN,tr|A0A140TA02|A0A140TA02_HUMAN,tr|A0A140T953|A0A140T953_HUMAN,tr|A0A140T921|A0A140T921_HUMAN,tr|A0A140T942|A0A140T942_HUMAN,tr|F8W9Z8|F8W9Z8_HUMAN,tr|A0A140TA05|A0A140TA05_HUMAN,tr|O19617|O19617_HUMAN,tr|Q53YP1|Q53YP1_HUMAN,tr|Q5RIP0|Q5RIP0_HUMAN,tr|A0A1W2PRZ0|A0A1W2PRZ0_HUMAN,tr|A0A0G2JH50|A0A0G2JH50_HUMAN,tr|A0A140T9E1|A0A140T9E1_HUMAN,tr|A0A140T9U0|A0A140T9U0_HUMAN,tr|F6U0H7|F6U0H7_HUMAN,tr|A0A1W2PNR7|A0A1W2PNR7_HUMAN,tr|A0A140T9Z7|A0A140T9Z7_HUMAN,tr|A0A140T9W2|A0A140T9W2_HUMAN,tr|A0A0G2JKJ1|A0A0G2JKJ1_HUMAN,tr|O78179|O78179_HUMAN,tr|S6AU73|S6AU73_HUMAN,tr|A2AEA2|A2AEA2_HUMAN,tr|A0A140T9T1|A0A140T9T1_HUMAN,tr|A0A140TA03|A0A140TA03_HUMAN,tr|A0A140TA13|A0A140TA13_HUMAN,tr|A2BF26|A2BF26_HUMAN,tr|A0A140T9H5|A0A140T9H5_HUMAN,tr|A0A0G2JIF0|A0A0G2JIF0_HUMAN,tr|Q5QT33|Q5QT33_HUMAN,tr|A0A140T9J9|A0A140T9J9_HUMAN,tr|A0A140T9Q4|A0A140T9Q4_HUMAN,tr|A0A140T9L3|A0A140T9L3_HUMAN,tr|A0A140T9B3|A0A140T9B3_HUMAN,tr|A0A140T9S7|A0A140T9S7_HUMAN,tr|Q5SS57|Q5SS57_HUMAN,tr|D9J307|D9J307_HUMAN,tr|A0A140TA21|A0A140TA21_HUMAN,tr|A0A140T9D4|A0A140T9D4_HUMAN,tr|A0A140T937|A0A140T937_HUMAN,tr|A0A140TA19|A0A140TA19_HUMAN,tr|A0A140T912|A0A140T912_HUMAN,tr|A0A140T962|A0A140T962_HUMAN,tr|A0A140T9M0|A0A140T9M0_HUMAN,tr|A0A140T9U8|A0A140T9U8_HUMAN,tr|A0A140TA12|A0A140TA12_HUMAN,tr|A0A1W2PR11|A0A1W2PR11_HUMAN,tr|A0A140T9M5|A0A140T9M5_HUMAN,tr|A0A140T930|A0A140T930_HUMAN,tr|A0A140T9Z4|A0A140T9Z4_HUMAN" 50 974.4333 2.02 41648 5327 2 974.436733 488.2239 "HLA class I histocompatibility antigen, B alpha chain OS=Homo sapiens OX=9606 GN=HLA-B PE=1 SV=3" 4.21 1605.1 - 151564 - - - 3.5292 - 1.096 0.179 - 98.6 1 2 0 0.0034 9 0 0 0 4.47E+07 2.21E+07 - - - 0.6272 0.8354 221125_WJC_METTL3_EV_vs_WT_F04.05332.05332.2 5.46 12-May R.EVESLEK.N "sp|Q8IX12|CCAR1_HUMAN,tr|F5H2E6|F5H2E6_HUMAN,tr|F5H1H2|F5H1H2_HUMAN,tr|A0A0C4DGG8|A0A0C4DGG8_HUMAN,tr|F5H3E1|F5H3E1_HUMAN" 5 832.4178 4.29 41649 5332 2 832.417279 417.2162 Cell division cycle and apoptosis regulator protein 1 OS=Homo sapiens OX=9606 GN=CCAR1 PE=1 SV=2 4.25 1605.9 - 1.17E+07 - - - -0.6427 - 0.895 0.042 - 97.5 3 2 0 -0.0005 7 0 0 0 2.54E+08 5.93E+07 - - - -1.2136 0.9977 221125_WJC_METTL3_EV_vs_WT_F04.05336.05336.2 0.416 14-Aug R.GGASIYGK[136.11].Q sp|Q9Y3C6|PPIL1_HUMAN 1 759.4007 0.001 41651 5336 2 759.400403 380.7076 Peptidyl-prolyl cis-trans isomerase-like 1 OS=Homo sapiens OX=9606 GN=PPIL1 PE=1 SV=1 8.59 1606.4 - 1.99E+06 - - - -0.3305 - 1.309 0.248 - 252.9 1 2 0 -0.0003 8 0 0 0 0.00E+00 1.31E+08 - - - 1.6847 0.9868 221125_WJC_METTL3_EV_vs_WT_F04.05337.05337.2 0.158 12-Aug R.AEQEIMK.K sp|Q9NZI8|IF2B1_HUMAN 1 847.411 0.89 41652 5337 2 847.408867 424.7128 Insulin-like growth factor 2 mRNA-binding protein 1 OS=Homo sapiens OX=9606 GN=IGF2BP1 PE=1 SV=2 4.53 1606.4 - 1.79E+06 - - - -2.4628 - 1.597 0.09 - 314.7 1 2 0 -0.0021 7 0 0 0 1.32E+08 1.48E+08 - - - 1.1884 0.8871 221125_WJC_METTL3_EV_vs_WT_F04.05340.05340.2 0.0184 20-Jun R.PAPAVGEAEDK.E sp|P16989|YBOX3_HUMAN 1 1082.5244 1.03 41653 5340 2 1082.526368 542.2695 Y-box-binding protein 3 OS=Homo sapiens OX=9606 GN=YBX3 PE=1 SV=4 4.14 1606.8 - 87934.1 - - - 1.8143 - 1.335 0.342 - 80.8 1 1 0 0.002 11 0 0 0 4.69E+06 4.54E+06 - - - 2.348 0.9459 221125_WJC_METTL3_EV_vs_WT_F04.05348.05348.2 0.0077 18-Oct K.PSPEPAAVSR.G sp|Q9H7S9|ZN703_HUMAN 1 1009.5193 1.72 41658 5348 2 1009.519195 505.7669 Zinc finger protein 703 OS=Homo sapiens OX=9606 GN=ZNF703 PE=1 SV=1 6.43 1607.7 - 675684 - - - -0.0634 - 1.61 0.276 - 295.5 1 1 0 -0.0001 10 0 0 0 1.04E+08 6.05E+07 - - - 2.4088 0.9998 221125_WJC_METTL3_EV_vs_WT_F04.05352.05352.2 0.000438 16-Aug R.TAQAAAALR.R "sp|P51570|GALK1_HUMAN,tr|K7EII7|K7EII7_HUMAN" 2 871.4876 1.6 41660 5352 2 871.48719 436.7511 Galactokinase OS=Homo sapiens OX=9606 GN=GALK1 PE=1 SV=1 9.41 1608.2 - 5.17E+06 - - - -0.4303 - 1.934 0.474 - 166.4 1 2 0 -0.0004 9 0 0 0 2.83E+08 1.77E+08 - - - 4.4501 0.9996 221125_WJC_METTL3_EV_vs_WT_F04.05353.05353.2 0.00346 16-Sep K.TSSSLATVK.K "sp|Q5TAP6|UT14C_HUMAN,sp|Q9BVJ6|UT14A_HUMAN" 2 892.4866 2.26 41661 5353 2 892.485813 447.2506 U3 small nucleolar RNA-associated protein 14 homolog C OS=Homo sapiens OX=9606 GN=UTP14C PE=1 SV=1 8.41 1608.3 - 573834 - - - -0.8392 - 1.664 0.377 - 300.9 1 2 0 -0.0007 9 0 0 0 1.15E+08 5.09E+07 - - - 3.2985 0.9693 221125_WJC_METTL3_EV_vs_WT_F04.05358.05358.2 4.39 12-Jun K.NSSVIVR[166.11].R "sp|Q7Z6E9|RBBP6_HUMAN,sp|Q8NI29|FBX27_HUMAN,tr|A0A2R8Y880|A0A2R8Y880_HUMAN,tr|I3L3Y2|I3L3Y2_HUMAN,tr|M0QYQ6|M0QYQ6_HUMAN,tr|H3BUN0|H3BUN0_HUMAN" 6 783.4478 0.78 41662 5358 2 783.447724 392.7312 E3 ubiquitin-protein ligase RBBP6 OS=Homo sapiens OX=9606 GN=RBBP6 PE=1 SV=1 9.75 1609 - 702900 - - - -0.1251 - 1.171 0.045 - 146.1 1 2 0 -0.0001 7 0 0 0 1.82E+07 2.34E+07 - - - -0.1265 0.9532 221125_WJC_METTL3_EV_vs_WT_F04.05360.05360.2 4.1 12-Jul K.NSSVIVR.R "sp|Q7Z6E9|RBBP6_HUMAN,sp|Q8NI29|FBX27_HUMAN,tr|A0A2R8Y880|A0A2R8Y880_HUMAN,tr|I3L3Y2|I3L3Y2_HUMAN,tr|M0QYQ6|M0QYQ6_HUMAN,tr|H3BUN0|H3BUN0_HUMAN" 6 773.4396 0.62 41663 5360 2 773.439783 387.7271 E3 ubiquitin-protein ligase RBBP6 OS=Homo sapiens OX=9606 GN=RBBP6 PE=1 SV=1 9.75 1609.3 - 527819 - - - 0.2987 - 0.994 0.111 - 144 3 2 0 0.0002 7 0 0 0 1.54E+07 2.48E+07 - - - -0.3714 0.9961 221125_WJC_METTL3_EV_vs_WT_F04.05362.05362.2 0.557 14-Jun R.LSVAGNC[160.03]R[166.11].M "sp|P28331|NDUS1_HUMAN,tr|F8WDL5|F8WDL5_HUMAN,tr|C9JPQ5|C9JPQ5_HUMAN" 3 885.4366 0.45 41664 5362 2 885.435814 443.7256 "NADH-ubiquinone oxidoreductase 75 kDa subunit, mitochondrial OS=Homo sapiens OX=9606 GN=NDUFS1 PE=1 SV=3" 8.25 1609.5 - 728652 - - - -0.8945 - 1.464 0.162 - 123.6 1 2 0 -0.0008 8 0 0 0 5.04E+07 1.12E+08 - - - 1.3869 0.8815 221125_WJC_METTL3_EV_vs_WT_F04.05368.05368.2 0.0698 12-Jun K.PSFESGR.R "sp|P38159|RBMX_HUMAN,tr|H3BT71|H3BT71_HUMAN,tr|H0Y6E7|H0Y6E7_HUMAN" 3 778.361 2.56 41668 5368 2 778.360311 390.1878 "RNA-binding motif protein, X chromosome OS=Homo sapiens OX=9606 GN=RBMX PE=1 SV=3" 6.43 1610.2 - 1.03E+06 - - - -0.8428 - 1.318 0.255 - 102.6 1 1 0 -0.0007 7 0 0 0 1.33E+08 5.19E+07 - - - 1.7991 0.9974 221125_WJC_METTL3_EV_vs_WT_F04.05369.05369.2 0.0802 14-Jul R.SMNSALGK[136.11].S "sp|Q13155|AIMP2_HUMAN,tr|A8MU58|A8MU58_HUMAN" 2 814.4098 1.71 41669 5369 2 814.40949 408.2122 Aminoacyl tRNA synthase complex-interacting multifunctional protein 2 OS=Homo sapiens OX=9606 GN=AIMP2 PE=1 SV=2 8.47 1610.3 - 992915 - - - -0.4273 - 1.189 0.275 - 148.9 1 2 0 -0.0003 8 0 0 0 8.66E+07 5.06E+07 - - - 1.5941 0.9912 221125_WJC_METTL3_EV_vs_WT_F04.05370.05370.2 0.116 16-Jul K.LIAAQTGTR[166.11].W sp|Q9BZL1|UBL5_HUMAN 1 939.5377 1.57 41670 5370 2 939.536549 470.7761 Ubiquitin-like protein 5 OS=Homo sapiens OX=9606 GN=UBL5 PE=1 SV=1 9.75 1610.4 - 956092 - - - -1.2251 - 1.502 0.111 - 111.6 2 2 0 -0.0012 9 0 0 0 1.59E+08 1.01E+08 - - - 0.9029 0.9997 221125_WJC_METTL3_EV_vs_WT_F04.05374.05374.2 0.0422 16-Aug K.LIAAQTGTR.W sp|Q9BZL1|UBL5_HUMAN 1 929.5294 1.57 41672 5374 2 929.528778 465.772 Ubiquitin-like protein 5 OS=Homo sapiens OX=9606 GN=UBL5 PE=1 SV=1 9.75 1611 - 1.56E+06 - - - -0.7014 - 1.714 0.426 - 152.8 1 2 0 -0.0007 9 0 0 0 1.59E+08 1.01E+08 - - - 3.7461 0.9942 221125_WJC_METTL3_EV_vs_WT_F04.05376.05376.2 0.224 12-Jul K.NQEVTIK[136.11].A "sp|Q13948|CASP_HUMAN,sp|P39880|CUX1_HUMAN,tr|A0A2R8Y8D0|A0A2R8Y8D0_HUMAN,tr|A0A2R8Y852|A0A2R8Y852_HUMAN,tr|A0A2R8YDI1|A0A2R8YDI1_HUMAN" 5 838.464 1.46 41674 5376 2 838.463538 420.2393 Protein CASP OS=Homo sapiens OX=9606 GN=CUX1 PE=1 SV=2 6 1611.1 - 2.48E+06 - - - -0.5295 - 1.464 0.105 - 305.7 1 2 0 -0.0004 7 0 0 0 1.61E+08 1.11E+08 - - - 1.0242 0.9995 221125_WJC_METTL3_EV_vs_WT_F04.05394.05394.2 0.00193 16-Oct K.LLATGSQDR[166.11].T "sp|Q12788|TBL3_HUMAN,tr|J3KNP2|J3KNP2_HUMAN,tr|A0A087WYP7|A0A087WYP7_HUMAN" 3 969.5119 1.2 41679 5394 2 969.511343 485.7632 Transducin beta-like protein 3 OS=Homo sapiens OX=9606 GN=TBL3 PE=1 SV=2 5.84 1613.7 - 1.26E+06 - - - -0.5529 - 2.025 0.281 - 304.3 1 2 0 -0.0005 9 0 0 0 7.77E+07 6.47E+07 - - - 3.1575 0.9993 221125_WJC_METTL3_EV_vs_WT_F04.05398.05398.2 0.0197 16-Aug K.LLATGSQDR.T "sp|Q12788|TBL3_HUMAN,tr|J3KNP2|J3KNP2_HUMAN,tr|A0A087WYP7|A0A087WYP7_HUMAN" 3 959.5036 1.2 41681 5398 2 959.503465 480.7591 Transducin beta-like protein 3 OS=Homo sapiens OX=9606 GN=TBL3 PE=1 SV=2 5.84 1614.2 - 1.56E+06 - - - -0.1501 - 1.662 0.286 - 171.6 1 2 0 -0.0001 9 0 0 0 7.77E+07 6.49E+07 - - - 2.6231 0.9925 221125_WJC_METTL3_EV_vs_WT_F04.05399.05399.2 0.139 20-Jun K.LSPSGTGPTPR[166.11].S "sp|Q8TBB5|KLDC4_HUMAN,tr|H3BQH3|H3BQH3_HUMAN,tr|Q9UF94|Q9UF94_HUMAN" 3 1078.5646 0.99 41682 5399 2 1078.565973 540.2896 Kelch domain-containing protein 4 OS=Homo sapiens OX=9606 GN=KLHDC4 PE=1 SV=1 9.75 1614.3 - 125087 - - - 1.2331 - 1.246 0.197 - 131.2 1 2 0 0.0013 11 0 0 0 2.22E+07 2.24E+07 - - - 1.0906 0.9999 221125_WJC_METTL3_EV_vs_WT_F04.05405.05405.2 4.80E-05 16-Sep R.FDSDAASPR.E "sp|P01889|HLAB_HUMAN,sp|P10321|HLAC_HUMAN,tr|A0A140TA02|A0A140TA02_HUMAN,tr|A0A140T953|A0A140T953_HUMAN,tr|A0A140T921|A0A140T921_HUMAN,tr|A0A140T942|A0A140T942_HUMAN,tr|F8W9Z8|F8W9Z8_HUMAN,tr|A0A140TA05|A0A140TA05_HUMAN,tr|O19617|O19617_HUMAN,tr|Q53YP1|Q53YP1_HUMAN,tr|Q5RIP0|Q5RIP0_HUMAN,tr|A0A1W2PRZ0|A0A1W2PRZ0_HUMAN,tr|A0A0G2JH50|A0A0G2JH50_HUMAN,tr|A0A140T9E1|A0A140T9E1_HUMAN,tr|A0A140T9U0|A0A140T9U0_HUMAN,tr|F6U0H7|F6U0H7_HUMAN,tr|A0A1W2PNR7|A0A1W2PNR7_HUMAN,tr|A0A140T9Z7|A0A140T9Z7_HUMAN,tr|A0A140T9W2|A0A140T9W2_HUMAN,tr|A0A0G2JKJ1|A0A0G2JKJ1_HUMAN,tr|O78179|O78179_HUMAN,tr|S6AU73|S6AU73_HUMAN,tr|A2AEA2|A2AEA2_HUMAN,tr|A0A140T9T1|A0A140T9T1_HUMAN,tr|A0A140TA03|A0A140TA03_HUMAN,tr|A0A140TA13|A0A140TA13_HUMAN,tr|A2BF26|A2BF26_HUMAN,tr|A0A140T9H5|A0A140T9H5_HUMAN,tr|A0A0G2JIF0|A0A0G2JIF0_HUMAN,tr|Q5QT33|Q5QT33_HUMAN,tr|A0A140T9J9|A0A140T9J9_HUMAN,tr|A0A140T9Q4|A0A140T9Q4_HUMAN,tr|A0A140T9L3|A0A140T9L3_HUMAN,tr|A0A140T9B3|A0A140T9B3_HUMAN,tr|A0A140T9S7|A0A140T9S7_HUMAN,tr|Q5SS57|Q5SS57_HUMAN,tr|D9J307|D9J307_HUMAN,tr|A0A140TA21|A0A140TA21_HUMAN,tr|A0A140T9D4|A0A140T9D4_HUMAN,tr|A0A140T937|A0A140T937_HUMAN,tr|A0A140TA19|A0A140TA19_HUMAN,tr|A0A140T912|A0A140T912_HUMAN,tr|A0A140T962|A0A140T962_HUMAN,tr|A0A140T9M0|A0A140T9M0_HUMAN,tr|A0A140T9U8|A0A140T9U8_HUMAN,tr|A0A140TA12|A0A140TA12_HUMAN,tr|A0A1W2PR11|A0A1W2PR11_HUMAN,tr|A0A140T9M5|A0A140T9M5_HUMAN,tr|A0A140T930|A0A140T930_HUMAN,tr|A0A140T9Z4|A0A140T9Z4_HUMAN" 50 964.425 1.99 41684 5405 2 964.424142 483.2198 "HLA class I histocompatibility antigen, B alpha chain OS=Homo sapiens OX=9606 GN=HLA-B PE=1 SV=3" 4.21 1615.1 - 753021 - - - -0.9145 - 1.957 0.54 - 263.2 1 2 0 -0.0009 9 0 0 0 4.40E+07 2.21E+07 - - - 4.9716 0.9963 221125_WJC_METTL3_EV_vs_WT_F04.05406.05406.2 0.00629 14-Jul R.QEEEMMAK[136.11].E sp|P35579|MYH9_HUMAN 1 1002.4242 0.74 41685 5406 2 1002.420864 502.2194 Myosin-9 OS=Homo sapiens OX=9606 GN=MYH9 PE=1 SV=4 4.25 1615.3 - 155850 - - - -3.296 - 1.177 0.433 - 157.3 1 2 0 -0.0033 8 0 0 0 3.31E+07 4.46E+07 - - - 2.7296 0.9996 221125_WJC_METTL3_EV_vs_WT_F04.05410.05410.2 1.34 12-Jul K.LDDYQER.M "sp|Q14444|CAPR1_HUMAN,tr|E9PLA9|E9PLA9_HUMAN" 2 937.4141 1 41687 5410 2 937.413918 469.7143 Caprin-1 OS=Homo sapiens OX=9606 GN=CAPRIN1 PE=1 SV=2 4.03 1615.8 - 3.24E+06 - - - -0.2208 - 1.73 0.346 - 147.5 1 2 0 -0.0002 7 0 0 0 7.34E+08 7.35E+08 - - - 3.3332 0.9994 221125_WJC_METTL3_EV_vs_WT_F04.05415.05415.2 0.00527 16-Aug R.TTTESEVMK.Y "sp|P11586|C1TC_HUMAN,tr|F5H2F4|F5H2F4_HUMAN,tr|V9GYY3|V9GYY3_HUMAN" 3 1024.4747 0.97 41690 5415 2 1024.47531 513.2446 "C-1-tetrahydrofolate synthase, cytoplasmic OS=Homo sapiens OX=9606 GN=MTHFD1 PE=1 SV=4" 4.53 1616.3 - 318847 - - - 0.6179 - 1.41 0.392 - 224.4 1 2 0 0.0006 9 0 0 0 1.44E+07 1.49E+07 - - - 2.9301 0.9808 221125_WJC_METTL3_EV_vs_WT_F04.05426.05426.2 0.729 14-Jun R.TSIEVGVK.G sp|Q03052|PO3F1_HUMAN 1 831.4702 911.04 41694 5426 2 831.469873 416.7424 "POU domain, class 3, transcription factor 1 OS=Homo sapiens OX=9606 GN=POU3F1 PE=2 SV=3" 5.66 1617.8 - 8.92E+06 - - - -0.3728 - 1.218 0.075 - 130.2 1 2 0 -0.0003 8 0 0 0 3.88E+08 4.26E+05 - - - 0.1896 0.999 221125_WJC_METTL3_EV_vs_WT_F04.05432.05432.2 0.297 14-Aug K.MEEETEVR[166.11].E sp|Q9H307|PININ_HUMAN 1 1031.4469 1.86 41698 5432 2 1031.445193 516.7307 Pinin OS=Homo sapiens OX=9606 GN=PNN PE=1 SV=5 4.09 1618.6 - 243838 - - - -1.6501 - 1.617 0.327 - 325.9 1 2 0 -0.0017 8 0 0 0 1.69E+08 9.11E+07 - - - 2.9051 0.9982 221125_WJC_METTL3_EV_vs_WT_F04.05433.05433.2 0.183 14-Jul R.QEEEMMAK.E sp|P35579|MYH9_HUMAN 1 994.41 0.74 41699 5433 2 994.40998 498.2123 Myosin-9 OS=Homo sapiens OX=9606 GN=MYH9 PE=1 SV=4 4.25 1618.7 - 594952 - - - 0.0121 - 1.239 0.299 - 219.6 1 2 0 0 8 0 0 0 3.31E+07 4.45E+07 - - - 1.8957 0.9997 221125_WJC_METTL3_EV_vs_WT_F04.05440.05440.2 0.0344 14-Aug K.MEEETEVR.E sp|Q9H307|PININ_HUMAN 1 1021.4386 1.86 41703 5440 2 1021.438733 511.7266 Pinin OS=Homo sapiens OX=9606 GN=PNN PE=1 SV=5 4.09 1619.7 - 721710 - - - 0.1057 - 1.72 0.379 - 314 1 2 0 0.0001 8 0 0 0 1.69E+08 9.11E+07 - - - 3.4759 0.9218 221125_WJC_METTL3_EV_vs_WT_F04.05444.05444.2 0.0581 12-Jul K.YEDEINK.R "sp|P48668|K2C6C_HUMAN,sp|P05787|K2C8_HUMAN,sp|Q01546|K22O_HUMAN,sp|Q7Z794|K2C1B_HUMAN,sp|P12035|K2C3_HUMAN,sp|P04264|K2C1_HUMAN,sp|P04259|K2C6B_HUMAN,sp|P13647|K2C5_HUMAN,sp|P35908|K22E_HUMAN,sp|O95678|K2C75_HUMAN,sp|Q5XKE5|K2C79_HUMAN,sp|P02538|K2C6A_HUMAN,tr|F8VUG2|F8VUG2_HUMAN,tr|F8W0C6|F8W0C6_HUMAN,tr|F8VP67|F8VP67_HUMAN,tr|F8W1U3|F8W1U3_HUMAN,tr|H0YIN9|H0YIN9_HUMAN" 17 909.408 999 41705 5444 2 909.400793 455.7113 "Keratin, type II cytoskeletal 6C OS=Homo sapiens OX=9606 GN=KRT6C PE=1 SV=3" 4.14 1620.1 - 1.04E+06 - - - -7.8996 - 1.267 0.397 - 146.2 1 2 0 -0.0072 7 0 0 0 1.79E+09 0.00E+00 - - - 2.7208 0.9767 221125_WJC_METTL3_EV_vs_WT_F04.05448.05448.2 1.56 12-Aug K.MYEEHLK[136.11].R "sp|P84090|ERH_HUMAN,tr|G3V279|G3V279_HUMAN" 2 956.4517 2.22 41707 5448 2 956.450133 479.2331 Enhancer of rudimentary homolog OS=Homo sapiens OX=9606 GN=ERH PE=1 SV=1 5.38 1620.6 - 1.21E+06 - - - -1.6415 - 1.228 0.096 - 221.1 1 2 0 -0.0016 7 0 0 0 2.50E+09 1.13E+09 - - - 0.4003 0.9993 221125_WJC_METTL3_EV_vs_WT_F04.05452.05452.2 0.112 16-Oct R.VGTVIGSNK[136.11].L "sp|P09874|PARP1_HUMAN,tr|A0A7I2V3E1|A0A7I2V3E1_HUMAN" 2 881.5062 0.83 41710 5452 2 881.504358 441.7604 Poly [ADP-ribose] polymerase 1 OS=Homo sapiens OX=9606 GN=PARP1 PE=1 SV=4 8.72 1621.1 - 1.05E+07 - - - -2.0692 - 2.175 0.297 - 321.5 1 2 0 -0.0018 9 0 0 0 4.33E+08 5.22E+08 - - - 3.4821 0.9996 221125_WJC_METTL3_EV_vs_WT_F04.05456.05456.2 0.00444 14-Aug K.TSSAFVGK[136.11].T "sp|Q99460|PSMD1_HUMAN,tr|A0A7I2V4X0|A0A7I2V4X0_HUMAN,tr|A0A7I2V2K8|A0A7I2V2K8_HUMAN,tr|A0A7I2YQY1|A0A7I2YQY1_HUMAN,tr|A0A7I2V523|A0A7I2V523_HUMAN,tr|A0A7I2V641|A0A7I2V641_HUMAN,tr|H7BZR6|H7BZR6_HUMAN,tr|A0A7I2V491|A0A7I2V491_HUMAN,tr|A0A7I2YQI9|A0A7I2YQI9_HUMAN,tr|A0A7I2V262|A0A7I2V262_HUMAN,tr|A0A087WW66|A0A087WW66_HUMAN,tr|A0A7P0MW50|A0A7P0MW50_HUMAN,tr|A0A7I2V4A5|A0A7I2V4A5_HUMAN,tr|A0A7I2V5C8|A0A7I2V5C8_HUMAN,tr|A0A7I2V479|A0A7I2V479_HUMAN" 15 803.4269 0.48 41713 5456 2 803.426809 402.7207 26S proteasome non-ATPase regulatory subunit 1 OS=Homo sapiens OX=9606 GN=PSMD1 PE=1 SV=2 8.41 1621.5 - 2.53E+06 - - - -0.0747 - 1.537 0.401 - 291.1 1 2 0 -0.0001 8 0 0 0 8.66E+07 1.79E+08 - - - 3.2991 0.9963 221125_WJC_METTL3_EV_vs_WT_F04.05466.05466.2 0.0261 14-Aug K.VLALSQHK[136.11].F "sp|Q8TB72|PUM2_HUMAN,tr|A0A0C4DG68|A0A0C4DG68_HUMAN" 2 902.5429 1.46 41717 5466 2 902.54092 452.2787 Pumilio homolog 2 OS=Homo sapiens OX=9606 GN=PUM2 PE=1 SV=2 8.73 1622.8 - 780121 - - - -2.1949 - 1.419 0.26 - 212.7 1 2 0 -0.002 8 0 0 0 1.04E+08 7.13E+07 - - - 2.0162 0.9984 221125_WJC_METTL3_EV_vs_WT_F04.05471.05471.2 0.153 14-Jul K.VLALSQHK.F "sp|Q8TB72|PUM2_HUMAN,tr|A0A0C4DG68|A0A0C4DG68_HUMAN" 2 894.5287 1.48 41719 5471 2 894.52742 448.2716 Pumilio homolog 2 OS=Homo sapiens OX=9606 GN=PUM2 PE=1 SV=2 8.73 1623.4 - 991494 - - - -1.432 - 1.803 0.204 - 149.3 1 2 0 -0.0013 8 0 0 0 1.06E+08 7.14E+07 - - - 2.3251 0.9084 221125_WJC_METTL3_EV_vs_WT_F04.05474.05474.2 1.53 16-May K.LENAGGDLK[136.11].D sp|P49915|GUAA_HUMAN 1 923.4804 1.52 41721 5474 2 923.479175 462.7475 GMP synthase [glutamine-hydrolyzing] OS=Homo sapiens OX=9606 GN=GMPS PE=1 SV=1 4.37 1623.7 - 246467 - - - -1.2843 - 1 0.09 - 51.6 6 2 0 -0.0012 9 0 0 0 3.66E+07 2.40E+07 - - - -0.6422 0.9983 221125_WJC_METTL3_EV_vs_WT_F04.05489.05489.2 0.00313 18-Sep K.IPGTPGAGGR.L "sp|Q16514|TAF12_HUMAN,tr|A0A804HLG9|A0A804HLG9_HUMAN" 2 881.4719 1.75 41725 5489 2 881.469811 441.7432 Transcription initiation factor TFIID subunit 12 OS=Homo sapiens OX=9606 GN=TAF12 PE=1 SV=1 9.75 1625.8 - 3.36E+06 - - - -2.3869 - 1.536 0.355 - 209.4 1 2 0 -0.0021 10 0 0 0 4.17E+08 2.38E+08 - - - 2.8603 0.9982 221125_WJC_METTL3_EV_vs_WT_F04.05504.05504.2 0.0405 12-Jul R.NPDNYVR[166.11].E "sp|Q9NV06|DCA13_HUMAN,tr|E5RHM4|E5RHM4_HUMAN,tr|A0A087WT20|A0A087WT20_HUMAN,tr|B3KME9|B3KME9_HUMAN" 4 886.4172 1.35 41731 5504 2 886.415268 444.2159 DDB1- and CUL4-associated factor 13 OS=Homo sapiens OX=9606 GN=DCAF13 PE=1 SV=2 5.84 1627.8 - 1.11E+06 - - - -2.236 - 1.19 0.416 - 128.2 1 2 0 -0.002 7 0 0 0 8.50E+07 6.28E+07 - - - 2.6641 0.9978 221125_WJC_METTL3_EV_vs_WT_F04.05507.05507.2 0.000874 12-Aug K.SDSFAPK[136.11].T "sp|Q9Y2W1|TR150_HUMAN,tr|A0A3B3ITZ9|A0A3B3ITZ9_HUMAN" 2 758.369 0.001 41732 5507 2 758.368119 380.1918 Thyroid hormone receptor-associated protein 3 OS=Homo sapiens OX=9606 GN=THRAP3 PE=1 SV=2 5.55 1628.2 - 5.21E+06 - - - -1.1868 - 1.534 0.205 - 336.5 1 2 0 -0.0009 7 0 0 0 0.00E+00 5.57E+09 - - - 1.9106 0.9966 221125_WJC_METTL3_EV_vs_WT_F04.05508.05508.2 0.0314 12-Aug R.C[160.03]SVASIK.T sp|P20042|IF2B_HUMAN 1 763.3898 0.83 41733 5508 2 763.388582 382.7022 Eukaryotic translation initiation factor 2 subunit 2 OS=Homo sapiens OX=9606 GN=EIF2S2 PE=1 SV=2 8.22 1628.3 - 1.70E+06 - - - -1.6283 - 1.463 0.209 - 323.3 1 2 0 -0.0012 7 0 0 0 5.85E+07 7.06E+07 - - - 1.7899 0.9991 221125_WJC_METTL3_EV_vs_WT_F04.05515.05515.2 0.000725 12-Jul K.VFNDTC[160.03]R[166.11].S "sp|P42704|LPPRC_HUMAN,tr|A0A804HI14|A0A804HI14_HUMAN,tr|A0A804HL40|A0A804HL40_HUMAN,tr|A0A804HKJ0|A0A804HKJ0_HUMAN,tr|A0A804HKR3|A0A804HKR3_HUMAN,tr|A0A0C4DG06|A0A0C4DG06_HUMAN,tr|A0A804HIN4|A0A804HIN4_HUMAN,tr|A0A804HLG8|A0A804HLG8_HUMAN,tr|A0A804HIV5|A0A804HIV5_HUMAN,tr|A0A804HHY9|A0A804HHY9_HUMAN,tr|A0A804HJH8|A0A804HJH8_HUMAN,tr|B8ZZ38|B8ZZ38_HUMAN,tr|A0A804HI40|A0A804HI40_HUMAN,tr|A0A804HJZ1|A0A804HJZ1_HUMAN,tr|C9JCA9|C9JCA9_HUMAN,tr|A0A804HIQ7|A0A804HIQ7_HUMAN,tr|A0A804HK30|A0A804HK30_HUMAN,tr|A0A804HKI2|A0A804HKI2_HUMAN,tr|A0A804HIG4|A0A804HIG4_HUMAN,tr|A0A804HK02|A0A804HK02_HUMAN" 20 920.405 0.4 41736 5515 2 920.403656 461.2098 "Leucine-rich PPR motif-containing protein, mitochondrial OS=Homo sapiens OX=9606 GN=LRPPRC PE=1 SV=3" 5.8 1629.2 - 1.48E+06 - - - -1.4287 - 1.361 0.386 - 189.4 1 2 0 -0.0013 7 0 0 0 3.73E+07 9.33E+07 - - - 2.8682 0.9994 221125_WJC_METTL3_EV_vs_WT_F04.05518.05518.2 0.0256 16-Sep K.QGSATVGLK[136.11].S "sp|P25786|PSA1_HUMAN,tr|F5GX11|F5GX11_HUMAN,tr|F5H112|F5H112_HUMAN,tr|B4DEV8|B4DEV8_HUMAN" 4 867.4905 0.68 41737 5518 2 867.489078 434.7525 Proteasome subunit alpha type-1 OS=Homo sapiens OX=9606 GN=PSMA1 PE=1 SV=1 8.75 1629.6 - 4.84E+06 - - - -1.6749 - 1.765 0.37 - 398.1 1 2 0 -0.0015 9 0 0 0 1.85E+08 2.70E+08 - - - 3.4171 0.9993 221125_WJC_METTL3_EV_vs_WT_F04.05530.05530.2 0.0295 14-Oct K.TAAEDAIR[166.11].N "sp|Q9BWF3|RBM4_HUMAN,sp|Q9BQ04|RBM4B_HUMAN,tr|E9PM61|E9PM61_HUMAN,tr|D6R9K7|D6R9K7_HUMAN,tr|J3QRR5|J3QRR5_HUMAN,tr|E9PB51|E9PB51_HUMAN,tr|U3KQD5|U3KQD5_HUMAN,tr|E9PLB0|E9PLB0_HUMAN" 8 855.4326 1.47 41743 5530 2 855.431355 428.7236 RNA-binding protein 4 OS=Homo sapiens OX=9606 GN=RBM4 PE=1 SV=1 4.37 1631.1 - 2.41E+07 - - - -1.4157 - 1.766 0.306 - 207.4 1 2 0 -0.0012 8 0 0 0 5.52E+09 3.76E+09 - - - 3.016 0.9975 221125_WJC_METTL3_EV_vs_WT_F04.05531.05531.2 0.00559 16-Aug R.AISSSAISK.A "sp|Q8N684|CPSF7_HUMAN,tr|F5H669|F5H669_HUMAN" 2 862.476 1.23 41744 5531 2 862.474253 432.2453 Cleavage and polyadenylation specificity factor subunit 7 OS=Homo sapiens OX=9606 GN=CPSF7 PE=1 SV=1 8.8 1631.1 - 1.58E+06 - - - -2.0221 - 1.422 0.295 - 157.6 1 2 0 -0.0017 9 0 0 0 1.84E+08 1.49E+08 - - - 2.2379 0.9758 221125_WJC_METTL3_EV_vs_WT_F04.05534.05534.2 0.558 12-Jun K.NSPLVSR[166.11].L sp|P40926|MDHM_HUMAN 1 781.4322 1.18 41745 5534 2 781.431436 391.7234 "Malate dehydrogenase, mitochondrial OS=Homo sapiens OX=9606 GN=MDH2 PE=1 SV=3" 9.75 1631.5 - 265043 - - - -0.9419 - 1.212 0.102 - 111.5 4 2 0 -0.0007 7 0 0 0 1.05E+08 8.89E+07 - - - 0.1344 0.9995 221125_WJC_METTL3_EV_vs_WT_F04.05538.05538.2 0.0318 14-Aug K.TAAEDAIR.N "sp|Q9BWF3|RBM4_HUMAN,sp|Q9BQ04|RBM4B_HUMAN,tr|E9PM61|E9PM61_HUMAN,tr|D6R9K7|D6R9K7_HUMAN,tr|J3QRR5|J3QRR5_HUMAN,tr|E9PB51|E9PB51_HUMAN,tr|U3KQD5|U3KQD5_HUMAN,tr|E9PLB0|E9PLB0_HUMAN" 8 845.4243 1.45 41747 5538 2 845.423611 423.7194 RNA-binding protein 4 OS=Homo sapiens OX=9606 GN=RBM4 PE=1 SV=1 4.37 1632 - 2.72E+07 - - - -0.8102 - 1.653 0.339 - 241.9 1 2 0 -0.0007 8 0 0 0 5.58E+09 3.85E+09 - - - 3.0604 1 221125_WJC_METTL3_EV_vs_WT_F04.05539.05539.3 1.14E-06 14/52 K.K[136.11]GPGEVAGTVTGQK[136.11].R "sp|Q86U44|MTA70_HUMAN,tr|F5H6D8|F5H6D8_HUMAN,tr|H0YFV6|H0YFV6_HUMAN,tr|B4DTN4|B4DTN4_HUMAN" 4 1343.738 0 41748 5539 3 1343.736612 448.9199 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 8.59 1632 - 1.83E+06 - - - -1.0173 - 2.488 0.501 - 310.3 1 2 0 -0.0014 14 0 0 0 1.37E+06 5.28E+08 - - - 6.5476 0.9989 221125_WJC_METTL3_EV_vs_WT_F04.05543.05543.2 0.0148 14-Jun R.EC[160.03]LAETER.N "sp|O75956|CDKA2_HUMAN,sp|O14519|CDKA1_HUMAN" 2 1006.439 0.32 41750 5543 2 1006.43713 504.2268 Cyclin-dependent kinase 2-associated protein 2 OS=Homo sapiens OX=9606 GN=CDK2AP2 PE=1 SV=1 4.25 1632.5 - 413062 - - - -1.8183 - 1.426 0.375 - 198.7 1 2 0 -0.0018 8 0 0 0 2.80E+07 8.79E+07 - - - 2.8805 0.9894 221125_WJC_METTL3_EV_vs_WT_F04.05551.05551.2 1.38 14-Jun R.GLPTTTQR.V "tr|A0A7I2V4L7|A0A7I2V4L7_HUMAN,tr|A0A7I2V598|A0A7I2V598_HUMAN,tr|H0Y5F5|H0Y5F5_HUMAN,tr|H0Y6X6|H0Y6X6_HUMAN" 4 872.4716 1.06 41752 5551 2 872.471703 437.2431 Polyadenylate-binding protein OS=Homo sapiens OX=9606 GN=PABPC4 PE=1 SV=1 9.75 1633.7 - 3.64E+06 - - - 0.141 - 1.131 0.159 - 115.1 1 2 0 0.0001 8 0 0 0 3.66E+08 3.45E+08 - - - 0.5866 0.9983 221125_WJC_METTL3_EV_vs_WT_F04.05555.05555.2 0.025 12-Jul R.EAEEVYR[166.11].N "sp|Q9Y383|LC7L2_HUMAN,tr|A0A0A6YYJ8|A0A0A6YYJ8_HUMAN" 2 904.4166 0.89 41753 5555 2 904.415488 453.2156 Putative RNA-binding protein Luc7-like 2 OS=Homo sapiens OX=9606 GN=LUC7L2 PE=1 SV=2 4.25 1634.3 - 1.29E+06 - - - -1.2085 - 1.487 0.253 - 299.6 1 2 0 -0.0011 7 0 0 0 9.27E+07 1.05E+08 - - - 2.1665 0.9037 221125_WJC_METTL3_EV_vs_WT_F04.05557.05557.2 5.36 12-May R.IAQQLER.E "sp|Q96FZ7|CHMP6_HUMAN,sp|Q66GS9|CP135_HUMAN,tr|I3L4A1|I3L4A1_HUMAN" 3 856.4767 1.48 41754 5557 2 856.475713 429.2456 Charged multivesicular body protein 6 OS=Homo sapiens OX=9606 GN=CHMP6 PE=1 SV=3 6 1634.5 - 7.60E+06 - - - -1.1127 - 1.151 0.013 - 76.4 5 2 0 -0.001 7 0 0 0 3.73E+08 2.51E+08 - - - -0.7299 0.9998 221125_WJC_METTL3_EV_vs_WT_F04.05559.05559.2 0.000821 14-Aug R.DGEAPLDK.A "sp|O95983|MBD3_HUMAN,tr|K7EIE8|K7EIE8_HUMAN" 2 843.3974 0.57 41755 5559 2 843.397395 422.706 Methyl-CpG-binding domain protein 3 OS=Homo sapiens OX=9606 GN=MBD3 PE=1 SV=1 4.03 1634.7 - 6.45E+06 - - - -0.0202 - 1.746 0.426 - 408.7 1 2 0 0 8 0 0 0 9.65E+08 1.70E+09 - - - 3.8683 0.9975 221125_WJC_METTL3_EV_vs_WT_F04.05561.05561.2 0.135 14-Jul R.DGEAPLDK[136.11].A "sp|O95983|MBD3_HUMAN,tr|K7EIE8|K7EIE8_HUMAN" 2 851.4116 1.08 41757 5561 2 851.411689 426.7131 Methyl-CpG-binding domain protein 3 OS=Homo sapiens OX=9606 GN=MBD3 PE=1 SV=1 4.03 1634.9 - 4.82E+06 - - - 0.0904 - 1.568 0.164 - 279.2 1 2 0 0.0001 8 0 0 0 2.92E+08 2.69E+08 - - - 1.6089 0.9962 221125_WJC_METTL3_EV_vs_WT_F04.05564.05564.2 0.0543 14-Jul R.ELGC[160.03]SSVR[166.11].A "sp|Q9HA64|KT3K_HUMAN,tr|I3L3W5|I3L3W5_HUMAN,tr|I3L407|I3L407_HUMAN,tr|I3L139|I3L139_HUMAN" 4 916.4312 0.72 41758 5564 2 916.429491 459.2229 Ketosamine-3-kinase OS=Homo sapiens OX=9606 GN=FN3KRP PE=1 SV=2 6.09 1635.3 - 1.89E+06 - - - -1.8496 - 1.217 0.295 - 260.5 1 2 0 -0.0017 8 0 0 0 9.95E+07 1.39E+08 - - - 1.8116 0.9999 221125_WJC_METTL3_EV_vs_WT_F04.05566.05566.2 1.34E-06 16-Oct K.GC[160.03]EVVVSGK[136.11].L "sp|P23396|RS3_HUMAN,tr|H0YEU2|H0YEU2_HUMAN,tr|E9PSF4|E9PSF4_HUMAN,tr|E9PL09|E9PL09_HUMAN,tr|E9PJN9|E9PJN9_HUMAN" 5 941.4732 0.61 41760 5566 2 941.473137 471.7439 40S ribosomal protein S3 OS=Homo sapiens OX=9606 GN=RPS3 PE=1 SV=2 5.99 1635.4 - 1.95E+06 - - - -0.0319 - 1.987 0.59 - 560.1 1 2 0 0 9 0 0 0 1.62E+08 2.64E+08 - - - 5.3852 0.9994 221125_WJC_METTL3_EV_vs_WT_F04.05569.05569.2 0.00978 14-Aug K.EVEEDEYK.A "sp|P14625|ENPL_HUMAN,tr|A0A7P0T917|A0A7P0T917_HUMAN,tr|A0A7P0T823|A0A7P0T823_HUMAN,tr|A0A7P0TAE1|A0A7P0TAE1_HUMAN,tr|H0YIV0|H0YIV0_HUMAN,tr|A0A7P0TAY2|A0A7P0TAY2_HUMAN,tr|A0A087WT78|A0A087WT78_HUMAN,tr|A0A7P0TBC2|A0A7P0TBC2_HUMAN,tr|A0A7P0TAT8|A0A7P0TAT8_HUMAN" 9 1039.4346 0.99 41761 5569 2 1039.434885 520.7246 Endoplasmin OS=Homo sapiens OX=9606 GN=HSP90B1 PE=1 SV=1 3.91 1635.8 - 561392 - - - 0.2877 - 1.435 0.375 - 244.7 1 2 0 0.0003 8 0 0 0 2.88E+07 2.91E+07 - - - 2.8999 0.9966 221125_WJC_METTL3_EV_vs_WT_F04.05575.05575.2 0.0255 18-Aug R.VLATQPGPGR[166.11].G "sp|Q5JTH9|RRP12_HUMAN,tr|A0A087X0G0|A0A087X0G0_HUMAN" 2 1004.5642 1.15 41764 5575 2 1004.564134 503.2894 RRP12-like protein OS=Homo sapiens OX=9606 GN=RRP12 PE=1 SV=2 9.72 1636.5 - 649642 - - - -0.1145 - 1.283 0.221 - 243.9 1 2 0 -0.0001 10 0 0 0 3.16E+07 2.76E+07 - - - 1.3689 0.9844 221125_WJC_METTL3_EV_vs_WT_F04.05577.05577.2 1.12 14-Jul R.TTIAQQVK.G "sp|P46459|NSF_HUMAN,tr|K7EQD6|K7EQD6_HUMAN,tr|I3L0N3|I3L0N3_HUMAN,tr|I3L2G1|I3L2G1_HUMAN" 4 887.5076 0.87 41765 5577 2 887.50694 444.7611 Vesicle-fusing ATPase OS=Homo sapiens OX=9606 GN=NSF PE=1 SV=3 8.41 1636.7 - 1.18E+06 - - - -0.7797 - 1.29 0.078 - 164 1 2 0 -0.0007 8 0 0 0 7.40E+07 8.47E+07 - - - 0.3849 0.9992 221125_WJC_METTL3_EV_vs_WT_F04.05578.05578.2 0.113 14-Aug K.EVEEDEYK[136.11].A "sp|P14625|ENPL_HUMAN,tr|A0A7P0T917|A0A7P0T917_HUMAN,tr|A0A7P0T823|A0A7P0T823_HUMAN,tr|A0A7P0TAE1|A0A7P0TAE1_HUMAN,tr|H0YIV0|H0YIV0_HUMAN,tr|A0A7P0TAY2|A0A7P0TAY2_HUMAN,tr|A0A087WT78|A0A087WT78_HUMAN,tr|A0A7P0TBC2|A0A7P0TBC2_HUMAN,tr|A0A7P0TAT8|A0A7P0TAT8_HUMAN" 9 1047.4488 0.99 41766 5578 2 1047.447869 524.7317 Endoplasmin OS=Homo sapiens OX=9606 GN=HSP90B1 PE=1 SV=1 3.91 1636.8 - 698456 - - - -0.8755 - 1.383 0.369 - 243 1 2 0 -0.0009 8 0 0 0 2.88E+07 2.91E+07 - - - 2.7441 0.9923 221125_WJC_METTL3_EV_vs_WT_F04.05579.05579.2 0.263 14-Jul K.ELQNEVEK.Q "sp|Q86U42|PABP2_HUMAN,tr|B4DEH8|B4DEH8_HUMAN,tr|G3V4T2|G3V4T2_HUMAN,tr|A0A7I2V383|A0A7I2V383_HUMAN" 4 987.4873 1.2 41767 5579 2 987.4871 494.7509 Polyadenylate-binding protein 2 OS=Homo sapiens OX=9606 GN=PABPN1 PE=1 SV=3 4.25 1637 - 424904 - - - -0.1924 - 1.306 0.129 - 169.3 1 2 0 -0.0002 8 0 0 0 1.56E+08 1.30E+08 - - - 0.7989 0.9876 221125_WJC_METTL3_EV_vs_WT_F04.05595.05595.2 3.12 14-Jun K.EHC[160.03]LVGVK[136.11].G sp|Q86U44|MTA70_HUMAN 1 948.4942 0.17 41773 5595 2 948.493339 475.2544 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 6.83 1639 - 1.95E+06 - - - -0.9468 - 1.218 0.128 - 170.3 1 2 0 -0.0009 8 0 0 0 1.07E+07 6.34E+07 - - - 0.5809 0.9971 221125_WJC_METTL3_EV_vs_WT_F04.05596.05596.2 0.217 16-Jun R.TISSATVAR[166.11].M "sp|Q9UJA3|MCM8_HUMAN,tr|A0A494C100|A0A494C100_HUMAN" 2 914.5061 0.64 41774 5596 2 914.506347 458.2603 DNA helicase MCM8 OS=Homo sapiens OX=9606 GN=MCM8 PE=1 SV=2 9.41 1639.1 - 646470 - - - 0.3084 - 1.264 0.247 - 93.1 1 2 0 0.0003 9 0 0 0 2.12E+07 3.33E+07 - - - 1.543 0.9995 221125_WJC_METTL3_EV_vs_WT_F04.05608.05608.2 0.0248 16-Jun R.QVDQLTNDK.A "sp|P08670|VIME_HUMAN,tr|B0YJC4|B0YJC4_HUMAN" 2 1059.5197 3.17 41779 5608 2 1059.520073 530.7671 Vimentin OS=Homo sapiens OX=9606 GN=VIM PE=1 SV=4 4.21 1640.7 - 231960 - - - 0.3964 - 1.529 0.383 - 89.5 1 2 0 0.0004 9 0 0 0 5.62E+06 1.77E+06 - - - 3.0981 0.8919 221125_WJC_METTL3_EV_vs_WT_F04.05612.05612.2 0.377 12-Jun L.QGFSVDK.G "sp|Q6ZT12|UBR3_HUMAN,tr|H0Y3K2|H0Y3K2_HUMAN,tr|H7BZD8|H7BZD8_HUMAN" 3 779.3814 13.73 41781 5612 2 779.381729 390.698 E3 ubiquitin-protein ligase UBR3 OS=Homo sapiens OX=9606 GN=UBR3 PE=2 SV=2 5.84 1641.2 - 3.31E+06 - - - 0.4632 - 1.313 0.263 - 138.8 1 1 0 0.0004 7 0 0 0 1.41E+08 1.03E+07 - - - 1.8462 0.9915 221125_WJC_METTL3_EV_vs_WT_F04.05615.05615.2 0.627 12-Jun K.NLEQYNK[136.11].L sp|Q9UQE7|SMC3_HUMAN 1 915.4541 0.65 41782 5615 2 915.453957 458.7343 Structural maintenance of chromosomes protein 3 OS=Homo sapiens OX=9606 GN=SMC3 PE=1 SV=2 6 1641.6 - 880656 - - - -0.2065 - 1.108 0.184 - 89.3 1 2 0 -0.0002 7 0 0 0 1.16E+07 1.79E+07 - - - 0.7249 0.9974 221125_WJC_METTL3_EV_vs_WT_F04.05619.05619.2 1.18 16-Sep R.IQQIAEGEK[136.11].V "sp|Q14254|FLOT2_HUMAN,tr|E7EMK3|E7EMK3_HUMAN,tr|K7EKW9|K7EKW9_HUMAN,tr|J3QLD9|J3QLD9_HUMAN" 4 1022.5488 0.79 41783 5619 2 1022.548447 512.2817 Flotillin-2 OS=Homo sapiens OX=9606 GN=FLOT2 PE=1 SV=2 4.53 1642.2 - 317600 - - - -0.3208 - 1.691 0.14 - 193.1 1 2 0 -0.0003 9 0 0 0 2.02E+07 2.54E+07 - - - 1.5947 0.998 221125_WJC_METTL3_EV_vs_WT_F04.05630.05630.2 0.231 14-Jul R.VSADEDLK.L "sp|Q9UNH7|SNX6_HUMAN,tr|A0A0A0MRI2|A0A0A0MRI2_HUMAN" 2 875.4236 1.04 41790 5630 2 875.424323 438.7191 Sorting nexin-6 OS=Homo sapiens OX=9606 GN=SNX6 PE=1 SV=1 4.03 1643.4 - 2.41E+06 - - - 0.795 - 1.714 0.175 - 133.9 1 2 0 0.0007 8 0 0 0 7.42E+07 7.14E+07 - - - 1.9584 0.9878 221125_WJC_METTL3_EV_vs_WT_F04.05631.05631.2 0.372 14-Jun R.VSADEDLK[136.11].L "sp|Q9UNH7|SNX6_HUMAN,tr|A0A0A0MRI2|A0A0A0MRI2_HUMAN" 2 883.4378 1.04 41791 5631 2 883.436548 442.7262 Sorting nexin-6 OS=Homo sapiens OX=9606 GN=SNX6 PE=1 SV=1 4.03 1643.4 - 1.60E+06 - - - -1.4478 - 1.114 0.189 - 78.3 1 2 0 -0.0013 8 0 0 0 7.74E+07 7.41E+07 - - - 0.7621 0.9874 221125_WJC_METTL3_EV_vs_WT_F04.05634.05634.2 0.318 12-Jul K.IVQLKPR.N "sp|P15924|DESP_HUMAN,sp|Q9UPN3|MACF1_HUMAN,tr|H3BQK9|H3BQK9_HUMAN,tr|A0A7P0MQR8|A0A7P0MQR8_HUMAN,tr|E9PNZ4|E9PNZ4_HUMAN,tr|E9PLY5|E9PLY5_HUMAN,tr|H3BPE1|H3BPE1_HUMAN,tr|E9PLY0|E9PLY0_HUMAN,tr|A0A669KBB0|A0A669KBB0_HUMAN,tr|A0A590UJG2|A0A590UJG2_HUMAN,tr|A0A5F9ZGX0|A0A5F9ZGX0_HUMAN" 11 852.5545 25.79 41792 5634 2 852.554887 427.2845 Desmoplakin OS=Homo sapiens OX=9606 GN=DSP PE=1 SV=3 11 1643.8 - 1.43E+06 - - - 0.4281 - 1.338 0.074 - 219.8 1 2 0 0.0004 7 0 0 0 5.47E+07 2.12E+06 - - - 0.5101 0.9991 221125_WJC_METTL3_EV_vs_WT_F04.05635.05635.2 0.0423 12-Jul K.QALYGDK[136.11].K "sp|Q96P16|RPR1A_HUMAN,tr|A0A0C4DGQ6|A0A0C4DGQ6_HUMAN" 2 801.4112 1.03 41793 5635 2 801.41008 401.7129 Regulation of nuclear pre-mRNA domain-containing protein 1A OS=Homo sapiens OX=9606 GN=RPRD1A PE=1 SV=1 5.83 1643.9 - 981723 - - - -1.42 - 1.356 0.378 - 221.7 1 2 0 -0.0011 7 0 0 0 3.29E+07 3.20E+07 - - - 2.7975 0.9803 221125_WJC_METTL3_EV_vs_WT_F04.05640.05640.2 3.96 12-Jun R.FLEQQNK[136.11].L "sp|P08670|VIME_HUMAN,sp|Q9NSB2|KRT84_HUMAN,sp|P14136|GFAP_HUMAN,sp|Q14533|KRT81_HUMAN,sp|P48668|K2C6C_HUMAN,sp|P05787|K2C8_HUMAN,sp|Q01546|K22O_HUMAN,sp|P19013|K2C4_HUMAN,sp|Q8N1N4|K2C78_HUMAN,sp|P12035|K2C3_HUMAN,sp|P78386|KRT85_HUMAN,sp|P04259|K2C6B_HUMAN,sp|P13647|K2C5_HUMAN,sp|O43790|KRT86_HUMAN,sp|P78385|KRT83_HUMAN,sp|P08729|K2C7_HUMAN,sp|O95678|K2C75_HUMAN,sp|Q5XKE5|K2C79_HUMAN,sp|P02538|K2C6A_HUMAN,tr|A0A1W2PR46|A0A1W2PR46_HUMAN,tr|F8VUG2|F8VUG2_HUMAN,tr|A0A087X106|A0A087X106_HUMAN,tr|A0A1X7SBR3|A0A1X7SBR3_HUMAN,tr|B4DIR1|B4DIR1_HUMAN,tr|K7EJU1|K7EJU1_HUMAN,tr|F8W0C6|F8W0C6_HUMAN,tr|A0A1X7SCE1|A0A1X7SCE1_HUMAN,tr|Q8IWY7|Q8IWY7_HUMAN,tr|U3KPR1|U3KPR1_HUMAN,tr|F8W1U3|F8W1U3_HUMAN,tr|K7EKH9|K7EKH9_HUMAN,tr|B0YJC4|B0YJC4_HUMAN,tr|K7ELP4|K7ELP4_HUMAN,tr|A0A1B0GTT5|A0A1B0GTT5_HUMAN" 34 913.4749 5.86 41796 5640 2 913.474008 457.7447 Vimentin OS=Homo sapiens OX=9606 GN=VIM PE=1 SV=4 6 1644.5 - 1.52E+06 - - - -0.9557 - 1.075 0.154 - 90.9 2 2 0 -0.0009 7 0 0 0 3.12E+10 5.33E+09 - - - 0.2729 0.9999 221125_WJC_METTL3_EV_vs_WT_F04.05641.05641.2 4.75E-06 17/26 K.K[136.11]GPGEVAGTVTGQK[136.11].R "sp|Q86U44|MTA70_HUMAN,tr|F5H6D8|F5H6D8_HUMAN,tr|H0YFV6|H0YFV6_HUMAN,tr|B4DTN4|B4DTN4_HUMAN" 4 1343.738 0.001 41797 5641 2 1343.737958 672.8763 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 8.59 1644.6 - 1.00E+06 - - - -0.0156 - 2.922 0.518 - 347.3 1 2 0 0 14 0 0 0 0.00E+00 9.69E+07 - - - 5.5577 0.9997 221125_WJC_METTL3_EV_vs_WT_F04.05647.05647.2 0.00189 18-Aug K.EVMSPTGSAR[166.11].G "sp|O43347|MSI1H_HUMAN,tr|H0YHB7|H0YHB7_HUMAN" 2 1043.4945 1.42 41800 5647 2 1043.495767 522.7545 RNA-binding protein Musashi homolog 1 OS=Homo sapiens OX=9606 GN=MSI1 PE=1 SV=1 6.1 1645.5 - 249066 - - - 1.2008 - 1.457 0.534 - 262.2 1 2 0 0.0013 10 0 0 0 3.13E+08 2.21E+08 - - - 4.0353 0.9991 221125_WJC_METTL3_EV_vs_WT_F04.05650.05650.2 0.000292 16-Sep K.AAPAEIDQR.- "sp|Q9UPW6|SATB2_HUMAN,tr|C9JR56|C9JR56_HUMAN" 2 969.488 2.56 41801 5650 2 969.488691 485.7513 DNA-binding protein SATB2 OS=Homo sapiens OX=9606 GN=SATB2 PE=1 SV=2 4.37 1645.9 - 1.38E+06 - - - 0.755 - 1.599 0.308 - 296.1 1 2 0 0.0007 9 0 0 0 8.09E+07 3.16E+07 - - - 2.6736 0.9914 221125_WJC_METTL3_EV_vs_WT_F04.05652.05652.2 0.0745 18-Aug R.AAAMANNLQK[136.11].G "sp|Q14498|RBM39_HUMAN,tr|H0Y4X3|H0Y4X3_HUMAN,tr|A0A0U1RQH7|A0A0U1RQH7_HUMAN,tr|G3XAC6|G3XAC6_HUMAN" 4 1038.5372 6.62 41803 5652 2 1038.5413 520.2759 RNA-binding protein 39 OS=Homo sapiens OX=9606 GN=RBM39 PE=1 SV=2 8.8 1646.1 - 270181 - - - 3.9825 - 1.681 0.265 - 246.6 1 2 0 0.0041 10 0 0 0 1.00E+08 1.51E+07 - - - 2.4468 0.9988 221125_WJC_METTL3_EV_vs_WT_F04.05657.05657.2 0.36 16-Sep K.TGPTVTQVK.A "sp|Q13428|TCOF_HUMAN,tr|E7ETY2|E7ETY2_HUMAN,tr|H0Y8Y7|H0Y8Y7_HUMAN,tr|A0A3B3IS06|A0A3B3IS06_HUMAN,tr|A0A6I8PRA0|A0A6I8PRA0_HUMAN" 5 929.5182 1.04 41806 5657 2 929.517944 465.7664 Treacle protein OS=Homo sapiens OX=9606 GN=TCOF1 PE=1 SV=3 8.41 1646.7 - 928884 - - - -0.2711 - 1.648 0.233 - 261.9 1 2 0 -0.0003 9 0 0 0 4.84E+07 4.66E+07 - - - 2.2071 0.978 221125_WJC_METTL3_EV_vs_WT_F04.05658.05658.2 0.934 18-Jun K.EVMSPTGSAR.G "sp|O43347|MSI1H_HUMAN,tr|H0YHB7|H0YHB7_HUMAN" 2 1033.4862 1.42 41807 5658 2 1033.486784 517.7504 RNA-binding protein Musashi homolog 1 OS=Homo sapiens OX=9606 GN=MSI1 PE=1 SV=1 6.1 1646.9 - 698664 - - - 0.5225 - 1.049 0.151 - 102.5 2 2 0 0.0005 10 0 0 0 3.13E+08 2.20E+08 - - - 0.1552 0.9991 221125_WJC_METTL3_EV_vs_WT_F04.05662.05662.2 0.0658 14-Jul K.SGEINPVK.V "sp|Q9H7N4|SFR19_HUMAN,sp|Q9P1Y6|PHRF1_HUMAN,tr|B7ZM65|B7ZM65_HUMAN,tr|A0A0J9YYB5|A0A0J9YYB5_HUMAN,tr|A0A0J9YWD5|A0A0J9YWD5_HUMAN,tr|F8WEF5|F8WEF5_HUMAN,tr|E9PJ24|E9PJ24_HUMAN" 7 842.4498 1.4 41809 5662 2 842.449609 422.2322 "Splicing factor, arginine\serine-rich 19 OS=Homo sapiens OX=9606 GN=SCAF1 PE=1 SV=3" 5.72 1647.4 - 1.92E+06 - - - -0.2054 - 1.533 0.285 - 296 1 2 0 -0.0002 8 0 0 0 1.31E+08 9.40E+07 - - - 2.4345 0.9811 221125_WJC_METTL3_EV_vs_WT_F04.05664.05664.2 0.272 12-May K.MEQLEDK.L "sp|Q15643|TRIPB_HUMAN,tr|H0YJ97|H0YJ97_HUMAN" 2 891.4008 0.92 41811 5664 2 891.401267 446.7077 Thyroid receptor-interacting protein 11 OS=Homo sapiens OX=9606 GN=TRIP11 PE=1 SV=3 4.14 1647.5 - 1.27E+06 - - - 0.543 - 1.098 0.143 - 93.1 2 2 0 0.0005 7 0 0 0 3.22E+07 3.51E+07 - - - 0.2588 0.9993 221125_WJC_METTL3_EV_vs_WT_F04.05667.05667.2 0.0329 16-Aug R.AAVLGENGR.V "sp|Q9UKM9|RALY_HUMAN,tr|Q5QPM2|Q5QPM2_HUMAN,tr|Q5QPM1|Q5QPM1_HUMAN,tr|Q5QPL9|Q5QPL9_HUMAN" 4 885.4668 1.3 41812 5667 2 885.467109 443.7407 RNA-binding protein Raly OS=Homo sapiens OX=9606 GN=RALY PE=1 SV=1 6.05 1647.9 - 1.38E+06 - - - 0.3162 - 1.718 0.281 - 207.3 1 2 0 0.0003 9 0 0 0 2.44E+08 1.87E+08 - - - 2.682 0.9995 221125_WJC_METTL3_EV_vs_WT_F04.05673.05673.2 1.06 14-Aug R.LEDYQANR.K "sp|P52948|NUP98_HUMAN,tr|A0A3B3ITD8|A0A3B3ITD8_HUMAN" 2 1007.4672 2.01 41817 5673 2 1007.466575 504.7409 Nuclear pore complex protein Nup98-Nup96 OS=Homo sapiens OX=9606 GN=NUP98 PE=1 SV=4 4.37 1648.5 - 1.80E+07 - - - -0.6432 - 1.92 0.291 - 237.2 1 2 0 -0.0006 8 0 0 0 3.77E+08 1.88E+08 - - - 3.1575 0.9995 221125_WJC_METTL3_EV_vs_WT_F04.05675.05675.2 0.0147 14-Jul K.LTVNPGTK[136.11].S sp|P09874|PARP1_HUMAN 1 836.4847 0.98 41819 5675 2 836.484558 419.2496 Poly [ADP-ribose] polymerase 1 OS=Homo sapiens OX=9606 GN=PARP1 PE=1 SV=4 8.75 1648.7 - 1.17E+06 - - - -0.1913 - 1.661 0.34 - 138.3 1 2 0 -0.0002 8 0 0 0 4.88E+08 4.99E+08 - - - 3.0825 0.9992 221125_WJC_METTL3_EV_vs_WT_F04.05681.05681.2 0.0105 14-Aug K.SGEINPVK[136.11].V "sp|Q9H7N4|SFR19_HUMAN,sp|Q9P1Y6|PHRF1_HUMAN,tr|B7ZM65|B7ZM65_HUMAN,tr|A0A0J9YYB5|A0A0J9YYB5_HUMAN,tr|A0A0J9YWD5|A0A0J9YWD5_HUMAN,tr|F8WEF5|F8WEF5_HUMAN,tr|E9PJ24|E9PJ24_HUMAN" 7 850.464 1.41 41823 5681 2 850.463873 426.2393 "Splicing factor, arginine\serine-rich 19 OS=Homo sapiens OX=9606 GN=SCAF1 PE=1 SV=3" 5.72 1649.3 - 1.71E+06 - - - -0.1282 - 1.594 0.288 - 316.3 1 2 0 -0.0001 8 0 0 0 1.33E+08 9.43E+07 - - - 2.5743 0.9355 221125_WJC_METTL3_EV_vs_WT_F04.05682.05682.2 0.00199 14-Jun L.GTNTIMDK.M "sp|Q00839|HNRPU_HUMAN,tr|A0A1W2PQL0|A0A1W2PQL0_HUMAN,tr|A0A1W2PPL4|A0A1W2PPL4_HUMAN,tr|A0A1W2PQ74|A0A1W2PQ74_HUMAN,tr|Q5RI18|Q5RI18_HUMAN,tr|A0A1W2PP35|A0A1W2PP35_HUMAN,tr|A0A1W2PPS1|A0A1W2PPS1_HUMAN,tr|A0A1W2PRZ7|A0A1W2PRZ7_HUMAN,tr|A0A1W2PPH7|A0A1W2PPH7_HUMAN,tr|A0A1W2PQD4|A0A1W2PQD4_HUMAN,tr|A0A1W2PP34|A0A1W2PP34_HUMAN,tr|A0A1X7SBS1|A0A1X7SBS1_HUMAN" 12 878.4168 0.63 41824 5682 2 878.414487 440.2157 Heterogeneous nuclear ribonucleoprotein U OS=Homo sapiens OX=9606 GN=HNRNPU PE=1 SV=6 5.84 1649.4 - 1.53E+06 - - - -2.5967 - 1.518 0.422 - 134 1 1 0 -0.0023 8 0 0 0 1.22E+08 1.94E+08 - - - 3.416 0.9963 221125_WJC_METTL3_EV_vs_WT_F04.05683.05683.2 0.632 12-Jun R.DYAPPPR.D "sp|Q96E39|RMXL1_HUMAN,sp|P38159|RBMX_HUMAN,tr|H3BUY5|H3BUY5_HUMAN,tr|H3BT71|H3BT71_HUMAN,tr|H0Y6E7|H0Y6E7_HUMAN" 5 814.3974 1.63 41825 5683 2 814.397054 408.206 "RNA binding motif protein, X-linked-like-1 OS=Homo sapiens OX=9606 GN=RBMXL1 PE=1 SV=1" 5.84 1649.4 - 1.97E+06 - - - -0.3671 - 1.184 0.236 - 182.8 1 2 0 -0.0003 7 0 0 0 1.58E+09 9.69E+08 - - - 1.3192 0.9988 221125_WJC_METTL3_EV_vs_WT_F04.05684.05684.2 0.043 16-Jun K.ILEGTETTK.Y "sp|P82650|RT22_HUMAN,tr|G5E9W7|G5E9W7_HUMAN,tr|A0A7P0MKV3|A0A7P0MKV3_HUMAN,tr|H7C5F2|H7C5F2_HUMAN,tr|H7C5H3|H7C5H3_HUMAN" 5 990.5233 1.29 41826 5684 2 990.522188 496.2689 "28S ribosomal protein S22, mitochondrial OS=Homo sapiens OX=9606 GN=MRPS22 PE=1 SV=1" 4.53 1649.5 - 763630 - - - -1.164 - 1.388 0.329 - 85.6 1 2 0 -0.0012 9 0 0 0 3.50E+07 2.72E+07 - - - 2.4192 0.9827 221125_WJC_METTL3_EV_vs_WT_F04.05686.05686.2 28.1 12-Aug R.FLEQQNK.L "sp|P08670|VIME_HUMAN,sp|Q9NSB2|KRT84_HUMAN,sp|P14136|GFAP_HUMAN,sp|Q14533|KRT81_HUMAN,sp|P48668|K2C6C_HUMAN,sp|P05787|K2C8_HUMAN,sp|Q01546|K22O_HUMAN,sp|P19013|K2C4_HUMAN,sp|Q8N1N4|K2C78_HUMAN,sp|P12035|K2C3_HUMAN,sp|P78386|KRT85_HUMAN,sp|P04259|K2C6B_HUMAN,sp|P13647|K2C5_HUMAN,sp|O43790|KRT86_HUMAN,sp|P78385|KRT83_HUMAN,sp|P08729|K2C7_HUMAN,sp|O95678|K2C75_HUMAN,sp|Q5XKE5|K2C79_HUMAN,sp|P02538|K2C6A_HUMAN,tr|A0A1W2PR46|A0A1W2PR46_HUMAN,tr|F8VUG2|F8VUG2_HUMAN,tr|A0A087X106|A0A087X106_HUMAN,tr|A0A1X7SBR3|A0A1X7SBR3_HUMAN,tr|B4DIR1|B4DIR1_HUMAN,tr|K7EJU1|K7EJU1_HUMAN,tr|F8W0C6|F8W0C6_HUMAN,tr|A0A1X7SCE1|A0A1X7SCE1_HUMAN,tr|Q8IWY7|Q8IWY7_HUMAN,tr|U3KPR1|U3KPR1_HUMAN,tr|F8W1U3|F8W1U3_HUMAN,tr|K7EKH9|K7EKH9_HUMAN,tr|B0YJC4|B0YJC4_HUMAN,tr|K7ELP4|K7ELP4_HUMAN,tr|A0A1B0GTT5|A0A1B0GTT5_HUMAN" 34 905.4607 5.85 41827 5686 2 905.461445 453.7376 Vimentin OS=Homo sapiens OX=9606 GN=VIM PE=1 SV=4 6 1649.7 - 4.07E+08 - - - 0.8438 - 1.19 0.108 - 195.4 1 2 0 0.0008 7 0 0 0 3.12E+10 5.33E+09 - - - 0.3896 0.7697 221125_WJC_METTL3_EV_vs_WT_F04.05689.05689.2 2.26 12-May K.EGSYIQR[166.11].M sp|O60763|USO1_HUMAN 1 861.422 2.22 41830 5689 2 861.423584 431.7183 General vesicular transport factor p115 OS=Homo sapiens OX=9606 GN=USO1 PE=1 SV=2 6.1 1649.9 - 729458 - - - 1.8377 - 0.954 0.026 - 113 2 2 0 0.0016 7 0 0 0 3.52E+07 1.59E+07 - - - -1.0511 0.996 221125_WJC_METTL3_EV_vs_WT_F04.05695.05695.2 0.13 16-Jun R.VAEVAPEER.E sp|Q6IQ49|SDE2_HUMAN 1 998.5033 1.28 41834 5695 2 998.501372 500.2589 Replication stress response regulator SDE2 OS=Homo sapiens OX=9606 GN=SDE2 PE=1 SV=1 4.25 1650.6 - 1.51E+06 - - - -1.9059 - 1.67 0.172 - 128.9 1 2 0 -0.0019 9 0 0 0 4.07E+07 3.18E+07 - - - 1.7944 0.9995 221125_WJC_METTL3_EV_vs_WT_F04.05708.05708.2 0.000105 16-Oct R.GAMTSSMER[166.11].D "sp|Q9P2K5|MYEF2_HUMAN,tr|A0A0A0MR39|A0A0A0MR39_HUMAN,tr|A0A0C4DGV1|A0A0C4DGV1_HUMAN,tr|A0A087WUT0|A0A087WUT0_HUMAN,tr|H0YN19|H0YN19_HUMAN,tr|A0A0A0MQW0|A0A0A0MQW0_HUMAN" 6 978.4138 1.05 41843 5708 2 978.416366 490.2142 Myelin expression factor 2 OS=Homo sapiens OX=9606 GN=MYEF2 PE=1 SV=3 6 1652 - 1.12E+06 - - - 2.6011 - 1.775 0.507 - 330.2 1 2 0 0.0025 9 0 0 0 9.14E+07 8.68E+07 - - - 4.4449 0.9982 221125_WJC_METTL3_EV_vs_WT_F04.05714.05714.2 0.000545 20-Dec K.TVGVEPAADGK[136.11].G "sp|P46779|RL28_HUMAN,tr|H0YMF4|H0YMF4_HUMAN,tr|H0YLP6|H0YLP6_HUMAN,tr|H0YKD8|H0YKD8_HUMAN" 4 1050.5437 0.93 41847 5714 2 1050.539459 526.2791 60S ribosomal protein L28 OS=Homo sapiens OX=9606 GN=RPL28 PE=1 SV=3 4.37 1652.8 - 1.65E+06 - - - -4.0265 - 1.904 0.459 - 333.5 1 2 0 -0.0042 11 0 0 0 2.58E+08 2.79E+08 - - - 4.1719 0.8731 221125_WJC_METTL3_EV_vs_WT_F04.05715.05715.2 1.69 14-Jun K.ETIMNQEK.L "sp|P20290|BTF3_HUMAN,tr|A0A7I2V3T6|A0A7I2V3T6_HUMAN,tr|D6RDG3|D6RDG3_HUMAN,tr|A0A7I2YQL2|A0A7I2YQL2_HUMAN" 4 991.4644 0.27 41848 5715 2 991.462119 496.7395 Transcription factor BTF3 OS=Homo sapiens OX=9606 GN=BTF3 PE=1 SV=1 4.53 1652.9 - 1.51E+06 - - - -2.347 - 1.17 0.007 - 75.8 1 2 0 -0.0023 8 0 0 0 3.45E+07 1.29E+08 - - - -0.4345 0.9965 221125_WJC_METTL3_EV_vs_WT_F04.05718.05718.2 0.0616 16-Jun R.GAMTSSMER.D "sp|Q9P2K5|MYEF2_HUMAN,tr|A0A0A0MR39|A0A0A0MR39_HUMAN,tr|A0A0C4DGV1|A0A0C4DGV1_HUMAN,tr|A0A087WUT0|A0A087WUT0_HUMAN,tr|H0YN19|H0YN19_HUMAN,tr|A0A0A0MQW0|A0A0A0MQW0_HUMAN" 6 968.4056 0.78 41849 5718 2 968.402117 485.2101 Myelin expression factor 2 OS=Homo sapiens OX=9606 GN=MYEF2 PE=1 SV=3 6 1653.3 - 1.88E+06 - - - -3.546 - 1.251 0.445 - 87.3 1 2 0 -0.0034 9 0 0 0 6.64E+07 8.48E+07 - - - 2.9746 0.9994 221125_WJC_METTL3_EV_vs_WT_F04.05719.05719.2 0.00286 16-Oct R.LQAAYAGDK.A "sp|Q01082|SPTB2_HUMAN,tr|A0A087WUZ3|A0A087WUZ3_HUMAN" 2 935.4712 1.44 41850 5719 2 935.473054 468.7429 "Spectrin beta chain, non-erythrocytic 1 OS=Homo sapiens OX=9606 GN=SPTBN1 PE=1 SV=2" 5.83 1653.4 - 1.67E+06 - - - 1.9327 - 1.963 0.368 - 237.8 1 2 0 0.0018 9 0 0 0 5.34E+07 3.71E+07 - - - 3.7098 0.9995 221125_WJC_METTL3_EV_vs_WT_F04.05720.05720.2 0.0802 16-Sep R.AAVLGENGR[166.11].V "sp|Q9UKM9|RALY_HUMAN,tr|Q5QPM2|Q5QPM2_HUMAN,tr|Q5QPM1|Q5QPM1_HUMAN,tr|Q5QPL9|Q5QPL9_HUMAN" 4 895.4751 1.3 41851 5720 2 895.474679 448.7448 RNA-binding protein Raly OS=Homo sapiens OX=9606 GN=RALY PE=1 SV=1 6.05 1653.4 - 6.08E+06 - - - -0.469 - 2.008 0.27 - 330.7 1 2 0 -0.0004 9 0 0 0 2.44E+08 1.87E+08 - - - 3.0519 0.9983 221125_WJC_METTL3_EV_vs_WT_F04.05723.05723.2 2.04 14-Sep R.IEDEEC[160.03]VR[166.11].L "sp|Q6P1J9|CDC73_HUMAN,tr|A0A2R8Y640|A0A2R8Y640_HUMAN,tr|A0A2R8YHB3|A0A2R8YHB3_HUMAN,tr|A0A1B0GUB2|A0A1B0GUB2_HUMAN,tr|A0A3B3IRP5|A0A3B3IRP5_HUMAN" 5 1058.4578 1.22 41852 5723 2 1058.460252 530.2362 Parafibromin OS=Homo sapiens OX=9606 GN=CDC73 PE=1 SV=1 4 1653.8 - 1.23E+06 - - - 2.3213 - 1.788 0.28 - 274.4 1 2 0 0.0025 8 0 0 0 7.27E+07 5.97E+07 - - - 2.8609 0.9963 221125_WJC_METTL3_EV_vs_WT_F04.05727.05727.2 0.0727 14-Aug R.LEMEQAQK[136.11].A "sp|Q5UCC4|EMC10_HUMAN,tr|M0R2A0|M0R2A0_HUMAN" 2 983.4837 1.87 41854 5727 2 983.481433 492.7491 ER membrane protein complex subunit 10 OS=Homo sapiens OX=9606 GN=EMC10 PE=1 SV=1 4.53 1654.2 - 457632 - - - -2.3376 - 1.51 0.249 - 191.3 1 2 0 -0.0023 8 0 0 0 3.49E+07 1.86E+07 - - - 2.1223 0.9992 221125_WJC_METTL3_EV_vs_WT_F04.05731.05731.2 0.00174 14-Jul K.LTVNPGTK.S sp|P09874|PARP1_HUMAN 1 828.4705 0.98 41856 5731 2 828.469056 415.2425 Poly [ADP-ribose] polymerase 1 OS=Homo sapiens OX=9606 GN=PARP1 PE=1 SV=4 8.75 1654.7 - 9.34E+06 - - - -1.7647 - 1.607 0.371 - 149.9 1 2 0 -0.0015 8 0 0 0 4.88E+08 4.99E+08 - - - 3.2114 0.9933 221125_WJC_METTL3_EV_vs_WT_F04.05732.05732.2 3.29E-05 16-Sep R.VLVEQQQDR[166.11].A "sp|Q5TDH0|DDI2_HUMAN,tr|H0YI90|H0YI90_HUMAN,tr|H0YII4|H0YII4_HUMAN" 3 1123.5861 1.04 41857 5732 2 1123.580693 562.8003 Protein DDI1 homolog 2 OS=Homo sapiens OX=9606 GN=DDI2 PE=1 SV=1 4.37 1654.8 - 554789 - - - -4.8176 - 2.002 0.299 - 309.3 1 2 0 -0.0054 9 0 0 0 8.94E+06 8.57E+06 - - - 3.2559 0.9993 221125_WJC_METTL3_EV_vs_WT_F04.05735.05735.2 0.00493 20-Oct K.TVGVEPAADGK.G "sp|P46779|RL28_HUMAN,tr|H0YMF4|H0YMF4_HUMAN,tr|H0YLP6|H0YLP6_HUMAN,tr|H0YKD8|H0YKD8_HUMAN" 4 1042.5295 0.93 41858 5735 2 1042.528344 522.272 60S ribosomal protein L28 OS=Homo sapiens OX=9606 GN=RPL28 PE=1 SV=3 4.37 1655.2 - 5.32E+06 - - - -1.0983 - 1.724 0.327 - 186 1 2 0 -0.0011 11 0 0 0 2.58E+08 2.78E+08 - - - 2.9293 0.9999 221125_WJC_METTL3_EV_vs_WT_F04.05737.05737.2 1.39E-05 22-Oct K.IITGGAAAQDGR[166.11].L "sp|Q12959|DLG1_HUMAN,tr|A0A590UJZ4|A0A590UJZ4_HUMAN,tr|A0A590UJ18|A0A590UJ18_HUMAN,tr|A0A590UKA8|A0A590UKA8_HUMAN,tr|B4E2H8|B4E2H8_HUMAN,tr|A0A590UK48|A0A590UK48_HUMAN,tr|A0A590UK70|A0A590UK70_HUMAN,tr|A0A0C4DFT3|A0A0C4DFT3_HUMAN,tr|A0A590UJD9|A0A590UJD9_HUMAN,tr|A0A590UJ95|A0A590UJ95_HUMAN,tr|A0A590UJL2|A0A590UJL2_HUMAN,tr|A0A590UJ25|A0A590UJ25_HUMAN,tr|A0A590UJX2|A0A590UJX2_HUMAN,tr|A0A590UJ08|A0A590UJ08_HUMAN,tr|C9JN61|C9JN61_HUMAN,tr|A0A590UJ68|A0A590UJ68_HUMAN,tr|A0A590UK81|A0A590UK81_HUMAN,tr|E7EQD7|E7EQD7_HUMAN,tr|A0A590UK52|A0A590UK52_HUMAN,tr|A0A590UJ81|A0A590UJ81_HUMAN,tr|A0A590UJ86|A0A590UJ86_HUMAN,tr|A0A590UJR4|A0A590UJR4_HUMAN,tr|A0A590UJC5|A0A590UJC5_HUMAN,tr|A0A590UK02|A0A590UK02_HUMAN,tr|A0A590UJ64|A0A590UJ64_HUMAN,tr|A0A590UJ29|A0A590UJ29_HUMAN,tr|A0A590UJS9|A0A590UJS9_HUMAN,tr|H7C166|H7C166_HUMAN,tr|A0A590UJR5|A0A590UJR5_HUMAN,tr|C9IYP1|C9IYP1_HUMAN" 30 1138.597 1.23 41860 5737 2 1138.597193 570.3058 Disks large homolog 1 OS=Homo sapiens OX=9606 GN=DLG1 PE=1 SV=2 5.84 1655.3 - 423572 - - - 0.1642 - 1.904 0.553 - 274.4 1 2 0 0.0002 12 0 0 0 1.73E+07 1.40E+07 - - - 4.8198 0.9852 221125_WJC_METTL3_EV_vs_WT_F04.05740.05740.2 0.728 12-Jun K.AVVVC[160.03]PK[136.11].D "sp|Q00839|HNRPU_HUMAN,tr|A0A1W2PQL0|A0A1W2PQL0_HUMAN,tr|A0A1W2PPL4|A0A1W2PPL4_HUMAN,tr|A0A1W2PQ74|A0A1W2PQ74_HUMAN,tr|Q5RI18|Q5RI18_HUMAN,tr|A0A1W2PP35|A0A1W2PP35_HUMAN,tr|A0A1W2PPS1|A0A1W2PPS1_HUMAN,tr|A0A1W2PRZ7|A0A1W2PRZ7_HUMAN,tr|A0A1W2PPH7|A0A1W2PPH7_HUMAN,tr|A0A1W2PQD4|A0A1W2PQD4_HUMAN,tr|A0A1W2PP34|A0A1W2PP34_HUMAN,tr|A0A1X7SBS1|A0A1X7SBS1_HUMAN" 12 779.4455 0.96 41861 5740 2 779.444266 390.73 Heterogeneous nuclear ribonucleoprotein U OS=Homo sapiens OX=9606 GN=HNRNPU PE=1 SV=6 8.27 1655.7 - 1.19E+06 - - - -1.578 - 1.273 0.137 - 164.7 2 2 0 -0.0012 7 0 0 0 7.92E+07 8.27E+07 - - - 0.6828 0.9991 221125_WJC_METTL3_EV_vs_WT_F04.05741.05741.2 0.000208 22-Nov K.IITGGAAAQDGR.L "sp|Q12959|DLG1_HUMAN,tr|A0A590UJZ4|A0A590UJZ4_HUMAN,tr|A0A590UJ18|A0A590UJ18_HUMAN,tr|A0A590UKA8|A0A590UKA8_HUMAN,tr|B4E2H8|B4E2H8_HUMAN,tr|A0A590UK48|A0A590UK48_HUMAN,tr|A0A590UK70|A0A590UK70_HUMAN,tr|A0A0C4DFT3|A0A0C4DFT3_HUMAN,tr|A0A590UJD9|A0A590UJD9_HUMAN,tr|A0A590UJ95|A0A590UJ95_HUMAN,tr|A0A590UJL2|A0A590UJL2_HUMAN,tr|A0A590UJ25|A0A590UJ25_HUMAN,tr|A0A590UJX2|A0A590UJX2_HUMAN,tr|A0A590UJ08|A0A590UJ08_HUMAN,tr|C9JN61|C9JN61_HUMAN,tr|A0A590UJ68|A0A590UJ68_HUMAN,tr|A0A590UK81|A0A590UK81_HUMAN,tr|E7EQD7|E7EQD7_HUMAN,tr|A0A590UK52|A0A590UK52_HUMAN,tr|A0A590UJ81|A0A590UJ81_HUMAN,tr|A0A590UJ86|A0A590UJ86_HUMAN,tr|A0A590UJR4|A0A590UJR4_HUMAN,tr|A0A590UJC5|A0A590UJC5_HUMAN,tr|A0A590UK02|A0A590UK02_HUMAN,tr|A0A590UJ64|A0A590UJ64_HUMAN,tr|A0A590UJ29|A0A590UJ29_HUMAN,tr|A0A590UJS9|A0A590UJS9_HUMAN,tr|H7C166|H7C166_HUMAN,tr|A0A590UJR5|A0A590UJR5_HUMAN,tr|C9IYP1|C9IYP1_HUMAN" 30 1128.5887 1.23 41862 5741 2 1128.584205 565.3016 Disks large homolog 1 OS=Homo sapiens OX=9606 GN=DLG1 PE=1 SV=2 5.84 1655.9 - 551092 - - - -4.0147 - 2.308 0.537 - 306.5 1 2 0 -0.0045 12 0 0 0 1.73E+07 1.40E+07 - - - 5.2065 0.9996 221125_WJC_METTL3_EV_vs_WT_F04.05747.05747.2 0.0318 16-Sep R.VAEVAPEER[166.11].E sp|Q6IQ49|SDE2_HUMAN 1 1008.5115 1.32 41865 5747 2 1008.510259 505.263 Replication stress response regulator SDE2 OS=Homo sapiens OX=9606 GN=SDE2 PE=1 SV=1 4.25 1656.6 - 366552 - - - -1.2751 - 2.046 0.333 - 372.4 1 2 0 -0.0013 9 0 0 0 4.21E+07 3.19E+07 - - - 3.5712 0.9987 221125_WJC_METTL3_EV_vs_WT_F04.05752.05752.2 0.00114 14-Aug K.QMMEAATR.Q sp|O43395|PRPF3_HUMAN 1 936.4157 2.67 41868 5752 2 936.413836 469.2151 U4\U6 small nuclear ribonucleoprotein Prp3 OS=Homo sapiens OX=9606 GN=PRPF3 PE=1 SV=2 6 1657.1 - 836452 - - - -2.0141 - 1.367 0.388 - 166.8 1 2 0 -0.0019 8 0 0 0 3.44E+07 1.29E+07 - - - 2.849 0.9953 221125_WJC_METTL3_EV_vs_WT_F04.05753.05753.2 0.0579 12-Jun R.SPEDLER[166.11].G "sp|Q8N196|SIX5_HUMAN,sp|P06744|G6PI_HUMAN,tr|A0A2U3TZU2|A0A2U3TZU2_HUMAN" 3 854.4009 2.49 41869 5753 2 854.40261 428.2077 Homeobox protein SIX5 OS=Homo sapiens OX=9606 GN=SIX5 PE=1 SV=3 4.14 1657.2 - 1.39E+06 - - - 1.9651 - 1.339 0.243 - 150.1 1 2 0 0.0017 7 0 0 0 1.10E+08 4.43E+07 - - - 1.7602 0.9998 221125_WJC_METTL3_EV_vs_WT_F04.05754.05754.2 0.000108 18-Oct K.YLASAGEDQR[166.11].L sp|O75529|TAF5L_HUMAN 1 1118.5232 1.02 41870 5754 2 1118.52139 560.2689 TAF5-like RNA polymerase II p300\CBP-associated factor-associated factor 65 kDa subunit 5L OS=Homo sapiens OX=9606 GN=TAF5L PE=1 SV=1 4.37 1657.3 - 322300 - - - -1.5932 - 1.963 0.556 - 343.1 1 2 0 -0.0018 10 0 0 0 3.25E+07 3.18E+07 - - - 5.0297 0.9999 221125_WJC_METTL3_EV_vs_WT_F04.05758.05758.2 1.94E-05 18-Oct K.YLASAGEDQR.L sp|O75529|TAF5L_HUMAN 1 1108.5149 1.02 41871 5758 2 1108.51562 555.2647 TAF5-like RNA polymerase II p300\CBP-associated factor-associated factor 65 kDa subunit 5L OS=Homo sapiens OX=9606 GN=TAF5L PE=1 SV=1 4.37 1657.9 - 472260 - - - 0.6477 - 2.063 0.562 - 364.2 1 2 0 0.0007 10 0 0 0 3.25E+07 3.18E+07 - - - 5.2131 0.9832 221125_WJC_METTL3_EV_vs_WT_F04.05761.05761.2 0.0039 16-Aug V.AAEVYGTER.Q "sp|P02788|TRFL_HUMAN,tr|C9JCF5|C9JCF5_HUMAN,tr|E7EQB2|E7EQB2_HUMAN,tr|E7ER44|E7ER44_HUMAN" 4 994.472 3.08 41873 5761 2 994.471351 498.2433 Lactotransferrin OS=Homo sapiens OX=9606 GN=LTF PE=1 SV=6 4.53 1658.3 - 609694 - - - -0.6265 - 1.633 0.439 - 181.4 1 1 0 -0.0006 9 0 0 0 1.16E+07 3.76E+06 - - - 3.7021 0.8293 221125_WJC_METTL3_EV_vs_WT_F04.05765.05765.2 2.35 12-Jun K.SDSFAPK[136.11].T "sp|Q9Y2W1|TR150_HUMAN,tr|A0A3B3ITZ9|A0A3B3ITZ9_HUMAN" 2 758.369 0.001 41875 5765 2 758.366855 380.1918 Thyroid hormone receptor-associated protein 3 OS=Homo sapiens OX=9606 GN=THRAP3 PE=1 SV=2 5.55 1658.8 - 300339 - - - -2.8535 - 0.95 0.095 - 92.9 1 2 0 -0.0022 7 0 0 0 0.00E+00 1.68E+07 - - - -0.4205 0.9971 221125_WJC_METTL3_EV_vs_WT_F04.05766.05766.2 0.125 14-Jul R.NPAELAEK[136.11].S sp|P0C7T5|ATX1L_HUMAN 1 878.4589 2.13 41876 5766 2 878.457685 440.2367 Ataxin-1-like OS=Homo sapiens OX=9606 GN=ATXN1L PE=1 SV=1 4.53 1658.8 - 1.20E+06 - - - -1.3797 - 1.343 0.251 - 198.9 1 2 0 -0.0012 8 0 0 0 8.33E+07 3.91E+07 - - - 1.7839 0.9948 221125_WJC_METTL3_EV_vs_WT_F04.05770.05770.2 0.04 16-Aug R.ISQATAQIK[136.11].N "sp|Q86Y82|STX12_HUMAN,tr|B1AJQ6|B1AJQ6_HUMAN" 2 966.5589 1.17 41878 5770 2 966.557839 484.2867 Syntaxin-12 OS=Homo sapiens OX=9606 GN=STX12 PE=1 SV=1 8.75 1659.3 - 839833 - - - -1.1443 - 1.407 0.165 - 134.8 1 2 0 -0.0011 9 0 0 0 4.37E+07 3.75E+07 - - - 1.2472 0.9774 221125_WJC_METTL3_EV_vs_WT_F04.05771.05771.2 0.518 14-Jul R.LVDQNLNK.L sp|O60264|SMCA5_HUMAN 1 942.5134 0.94 41879 5771 2 942.511789 472.264 SWI\SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A member 5 OS=Homo sapiens OX=9606 GN=SMARCA5 PE=1 SV=1 5.84 1659.4 - 825385 - - - -1.757 - 1.126 0.145 - 124 1 2 0 -0.0017 8 0 0 0 8.08E+07 8.62E+07 - - - 0.4694 0.998 221125_WJC_METTL3_EV_vs_WT_F04.05774.05774.2 0.00598 16-Jun R.ATTLESNVK.K "sp|Q5VT06|CE350_HUMAN,tr|A2A4F6|A2A4F6_HUMAN,tr|E9PIK0|E9PIK0_HUMAN" 3 961.508 1.34 41880 5774 2 961.507305 481.7613 Centrosome-associated protein 350 OS=Homo sapiens OX=9606 GN=CEP350 PE=1 SV=1 6.05 1659.8 - 1.15E+06 - - - -0.7499 - 1.468 0.232 - 134.7 1 2 0 -0.0007 9 0 0 0 3.44E+07 2.57E+07 - - - 1.865 0.9968 221125_WJC_METTL3_EV_vs_WT_F04.05776.05776.2 0.000141 14-Sep R.YDDPEVQK[136.11].D "sp|P38646|GRP75_HUMAN,tr|H0Y8K0|H0Y8K0_HUMAN,tr|A0A7I2V2S7|A0A7I2V2S7_HUMAN,tr|A0A7I2V2G2|A0A7I2V2G2_HUMAN,tr|A0A3B3ITI4|A0A3B3ITI4_HUMAN,tr|A0A7I2V3F7|A0A7I2V3F7_HUMAN,tr|A0A7I2YQB2|A0A7I2YQB2_HUMAN,tr|D6RCD7|D6RCD7_HUMAN" 8 1000.4593 0.56 41882 5776 2 1000.454405 501.2369 "Stress-70 protein, mitochondrial OS=Homo sapiens OX=9606 GN=HSPA9 PE=1 SV=2" 4.03 1660 - 1.70E+06 - - - -4.8838 - 1.707 0.484 - 214.6 1 2 0 -0.0049 8 0 0 0 1.24E+08 2.21E+08 - - - 4.227 0.9982 221125_WJC_METTL3_EV_vs_WT_F04.05782.05782.2 0.0396 12-Aug R.GVQQLTR.L "sp|Q6P3W7|SCYL2_HUMAN,tr|F8VSC5|F8VSC5_HUMAN,tr|A0A0U1RQQ9|A0A0U1RQQ9_HUMAN" 3 800.4505 0.18 41886 5782 2 800.450485 401.2325 SCY1-like protein 2 OS=Homo sapiens OX=9606 GN=SCYL2 PE=1 SV=1 9.75 1660.8 - 1.04E+07 - - - 0.0425 - 1.544 0.2 - 261 1 2 0 0 7 0 0 0 3.32E+08 1.87E+09 - - - 1.8945 0.9717 221125_WJC_METTL3_EV_vs_WT_F04.05785.05785.2 0.303 14-Jun K.TEEVSNLK.T "sp|Q6PKG0|LARP1_HUMAN,tr|A0A0B4J210|A0A0B4J210_HUMAN,tr|H0YBW1|H0YBW1_HUMAN,tr|H0YC73|H0YC73_HUMAN,tr|E5RH50|E5RH50_HUMAN" 5 918.4658 1.03 41889 5785 2 918.463746 460.2402 La-related protein 1 OS=Homo sapiens OX=9606 GN=LARP1 PE=1 SV=2 4.53 1660.9 - 1.55E+06 - - - -2.2646 - 1.344 0.084 - 160.4 1 2 0 -0.0021 8 0 0 0 5.85E+07 5.70E+07 - - - 0.5524 0.843 221125_WJC_METTL3_EV_vs_WT_F04.05786.05786.2 1.35 18-Jun R.VLLGETGK[136.11]EK[136.11].L "sp|P62280|RS11_HUMAN,tr|M0QZC5|M0QZC5_HUMAN,tr|M0R1H6|M0R1H6_HUMAN" 3 1088.6412 2.74 41890 5786 2 1088.640774 545.3279 40S ribosomal protein S11 OS=Homo sapiens OX=9606 GN=RPS11 PE=1 SV=3 6.11 1661.1 - 427185 - - - -0.4143 - 1.322 0.065 - 88.3 1 2 1 -0.0005 10 0 0 0 1.08E+08 3.94E+07 - - - 0.3001 0.9993 221125_WJC_METTL3_EV_vs_WT_F04.05792.05792.2 0.046 12-Jun R.DYAPPPR[166.11].D "sp|Q96E39|RMXL1_HUMAN,sp|P38159|RBMX_HUMAN,tr|H3BUY5|H3BUY5_HUMAN,tr|H3BT71|H3BT71_HUMAN,tr|H0Y6E7|H0Y6E7_HUMAN" 5 824.4056 1.63 41892 5792 2 824.405462 413.2101 "RNA binding motif protein, X-linked-like-1 OS=Homo sapiens OX=9606 GN=RBMXL1 PE=1 SV=1" 5.84 1661.9 - 8.46E+06 - - - -0.1953 - 1.361 0.365 - 176.3 1 2 0 -0.0002 7 0 0 0 1.57E+09 9.65E+08 - - - 2.7135 0.9994 221125_WJC_METTL3_EV_vs_WT_F04.05793.05793.2 0.0525 16-Aug R.VLQTEQAVK[136.11].E "sp|Q9H7C9|AAMDC_HUMAN,tr|E9PNP3|E9PNP3_HUMAN,tr|E9PR47|E9PR47_HUMAN,tr|E9PIQ4|E9PIQ4_HUMAN" 4 1022.5852 1.64 41893 5793 2 1022.584751 512.2999 Mth938 domain-containing protein OS=Homo sapiens OX=9606 GN=AAMDC PE=1 SV=1 5.97 1662 - 704760 - - - -0.4 - 1.656 0.316 - 166.7 1 2 0 -0.0004 9 0 0 0 7.28E+08 4.43E+08 - - - 2.8341 0.9981 221125_WJC_METTL3_EV_vs_WT_F04.05794.05794.2 0.115 14-Jul K.AAVDGLSK.M sp|Q13155|AIMP2_HUMAN 1 759.4127 0.81 41894 5794 2 759.41287 380.7136 Aminoacyl tRNA synthase complex-interacting multifunctional protein 2 OS=Homo sapiens OX=9606 GN=AIMP2 PE=1 SV=2 5.88 1662.1 - 442564 - - - 0.2647 - 1.567 0.195 - 166.4 1 2 0 0.0002 8 0 0 0 4.75E+07 5.87E+07 - - - 1.8359 0.9572 221125_WJC_METTL3_EV_vs_WT_F04.05801.05801.2 2.48 16-May K.VETQTEELK[136.11].Q "sp|Q6KC79|NIPBL_HUMAN,tr|A0A590UJS4|A0A590UJS4_HUMAN" 2 1083.5539 1.35 41898 5801 2 1083.553892 542.7842 Nipped-B-like protein OS=Homo sapiens OX=9606 GN=NIPBL PE=1 SV=2 4.25 1663.1 - 136858 - - - -0.0258 - 1.232 0.06 - 52.5 9 2 0 0 9 0 0 0 1.64E+07 1.21E+07 - - - -0.3385 0.9318 221125_WJC_METTL3_EV_vs_WT_F04.05808.05808.2 0.359 18-Sep R.VLLGETGKEK.L "sp|P62280|RS11_HUMAN,tr|M0QZC5|M0QZC5_HUMAN,tr|M0R1H6|M0R1H6_HUMAN" 3 1072.6128 3.24 41902 5808 2 1072.613523 537.3137 40S ribosomal protein S11 OS=Homo sapiens OX=9606 GN=RPS11 PE=1 SV=3 6.11 1663.9 - 1.51E+06 - - - 0.6507 - 1.437 0.13 - 109.9 1 2 1 0.0007 10 0 0 0 1.28E+08 3.95E+07 - - - 1.013 0.9998 221125_WJC_METTL3_EV_vs_WT_F04.05811.05811.2 0.000141 22-Nov K.IVQAEGEAEAAK[136.11].M "sp|Q99623|PHB2_HUMAN,tr|F5H3X6|F5H3X6_HUMAN,tr|F5GY37|F5GY37_HUMAN" 3 1222.6285 1.31 41905 5811 2 1222.629221 612.3215 Prohibitin-2 OS=Homo sapiens OX=9606 GN=PHB2 PE=1 SV=2 4.25 1664.2 - 226892 - - - 0.6044 - 2.073 0.485 - 383.4 1 2 0 0.0007 12 0 0 0 6.01E+08 4.60E+08 - - - 4.5411 0.9207 221125_WJC_METTL3_EV_vs_WT_F04.05816.05816.2 4.43 14-Jun K.LQQELGGR.L "sp|Q96T51|RUFY1_HUMAN,tr|H0YA47|H0YA47_HUMAN" 2 899.4825 0.64 41908 5816 2 899.48299 450.7485 RUN and FYVE domain-containing protein 1 OS=Homo sapiens OX=9606 GN=RUFY1 PE=1 SV=2 6 1664.8 - 839549 - - - 0.5681 - 1.149 0 - 114.5 2 2 0 0.0005 8 0 0 0 9.61E+07 1.49E+08 - - - -0.6747 0.9991 221125_WJC_METTL3_EV_vs_WT_F04.05820.05820.2 1.37 12-Jul K.ITITNDK[136.11].G "sp|P54652|HSP72_HUMAN,sp|P0DMV8|HS71A_HUMAN,sp|P34931|HS71L_HUMAN,sp|P11142|HSP7C_HUMAN,sp|P0DMV9|HS71B_HUMAN,sp|P17066|HSP76_HUMAN,tr|E9PNE6|E9PNE6_HUMAN,tr|A8K7Q2|A8K7Q2_HUMAN,tr|E9PKE3|E9PKE3_HUMAN,tr|E9PM13|E9PM13_HUMAN,tr|E9PS65|E9PS65_HUMAN,tr|Q53FA3|Q53FA3_HUMAN,tr|V9GZ37|V9GZ37_HUMAN,tr|A0A0G2JIW1|A0A0G2JIW1_HUMAN" 14 811.4531 0.15 41910 5820 2 811.453416 406.7338 Heat shock-related 70 kDa protein 2 OS=Homo sapiens OX=9606 GN=HSPA2 PE=1 SV=1 5.84 1665.2 - 2.46E+07 - - - 0.4104 - 1.563 0.28 - 163.2 1 2 0 0.0003 7 0 0 0 7.83E+09 5.09E+10 - - - 2.5241 0.9999 221125_WJC_METTL3_EV_vs_WT_F04.05821.05821.2 3.50E-06 22-Dec K.IVQAEGEAEAAK.M "sp|Q99623|PHB2_HUMAN,tr|F5H3X6|F5H3X6_HUMAN,tr|F5GY37|F5GY37_HUMAN" 3 1214.6143 1.31 41911 5821 2 1214.613556 608.3144 Prohibitin-2 OS=Homo sapiens OX=9606 GN=PHB2 PE=1 SV=2 4.25 1665.3 - 1.36E+06 - - - -0.5977 - 2.146 0.491 - 437.5 1 2 0 -0.0007 12 0 0 0 6.01E+08 4.60E+08 - - - 4.6765 0.9993 221125_WJC_METTL3_EV_vs_WT_F04.05822.05822.2 0.032 14-Aug R.TVTEIDEK.E "sp|P61289|PSME3_HUMAN,tr|B3KQ25|B3KQ25_HUMAN,tr|K7ESG5|K7ESG5_HUMAN,tr|K9J957|K9J957_HUMAN,tr|A0A087WTV2|A0A087WTV2_HUMAN" 5 933.4655 1.24 41912 5822 2 933.465745 467.74 Proteasome activator complex subunit 3 OS=Homo sapiens OX=9606 GN=PSME3 PE=1 SV=1 4.14 1665.4 - 1.80E+06 - - - 0.271 - 1.657 0.299 - 192.8 1 2 0 0.0003 8 0 0 0 5.89E+07 4.75E+07 - - - 2.7724 0.9831 221125_WJC_METTL3_EV_vs_WT_F04.05832.05832.2 0.0264 14-Jul K.AFAETHIK[136.11].G "sp|P42704|LPPRC_HUMAN,tr|A0A804HI14|A0A804HI14_HUMAN,tr|A0A804HL40|A0A804HL40_HUMAN,tr|A0A804HKJ0|A0A804HKJ0_HUMAN,tr|A0A804HKR3|A0A804HKR3_HUMAN,tr|A0A804HIN4|A0A804HIN4_HUMAN,tr|A0A804HLG8|A0A804HLG8_HUMAN,tr|A0A804HJA1|A0A804HJA1_HUMAN,tr|A0A804HHY9|A0A804HHY9_HUMAN,tr|A0A804HI40|A0A804HI40_HUMAN,tr|A0A804HJZ1|A0A804HJZ1_HUMAN,tr|A0A804HIQ7|A0A804HIQ7_HUMAN,tr|A0A804HK30|A0A804HK30_HUMAN,tr|A0A804HKI2|A0A804HKI2_HUMAN,tr|A0A804HJI0|A0A804HJI0_HUMAN,tr|A0A804HKX6|A0A804HKX6_HUMAN,tr|A0A804HKK7|A0A804HKK7_HUMAN,tr|A0A804HIG4|A0A804HIG4_HUMAN" 18 923.4956 2.19 41918 5832 2 923.491577 462.7551 "Leucine-rich PPR motif-containing protein, mitochondrial OS=Homo sapiens OX=9606 GN=LRPPRC PE=1 SV=3" 6.79 1666.5 - 679640 - - - -4.3747 - 1.332 0.295 - 137.5 1 2 0 -0.004 8 0 0 0 5.27E+07 2.41E+07 - - - 2.0832 0.9995 221125_WJC_METTL3_EV_vs_WT_F04.05842.05842.2 0.000369 16-Sep R.VLQTEQAVK.E "sp|Q9H7C9|AAMDC_HUMAN,tr|E9PNP3|E9PNP3_HUMAN,tr|E9PR47|E9PR47_HUMAN,tr|E9PIQ4|E9PIQ4_HUMAN" 4 1014.571 1.64 41924 5842 2 1014.569806 508.2928 Mth938 domain-containing protein OS=Homo sapiens OX=9606 GN=AAMDC PE=1 SV=1 5.97 1667.8 - 2.35E+07 - - - -1.1374 - 1.599 0.396 - 232.6 1 2 0 -0.0012 9 0 0 0 7.28E+08 4.43E+08 - - - 3.3234 0.9983 221125_WJC_METTL3_EV_vs_WT_F04.05843.05843.2 0.116 12-May K.LC[160.03]QPYGK.L "sp|Q15434|RBMS2_HUMAN,sp|Q6XE24|RBMS3_HUMAN,sp|P29558|RBMS1_HUMAN,tr|C9JIJ9|C9JIJ9_HUMAN,tr|C9J9B2|C9J9B2_HUMAN,tr|E7ETU5|E7ETU5_HUMAN,tr|F6Y5H0|F6Y5H0_HUMAN,tr|E7EPF2|E7EPF2_HUMAN,tr|A0A1B0GUW5|A0A1B0GUW5_HUMAN,tr|F8W1T6|F8W1T6_HUMAN" 10 864.4164 1.66 41925 5843 2 864.415146 433.2155 "RNA-binding motif, single-stranded-interacting protein 2 OS=Homo sapiens OX=9606 GN=RBMS2 PE=1 SV=1" 8.2 1667.9 - 2.76E+06 - - - -1.4206 - 1.144 0.377 - 79.5 1 2 0 -0.0012 7 0 0 0 2.29E+08 1.38E+08 - - - 2.2514 0.9974 221125_WJC_METTL3_EV_vs_WT_F04.05845.05845.2 0.0244 14-Jul R.TVTEIDEK[136.11].E "sp|P61289|PSME3_HUMAN,tr|B3KQ25|B3KQ25_HUMAN,tr|K7ESG5|K7ESG5_HUMAN,tr|K9J957|K9J957_HUMAN,tr|A0A087WTV2|A0A087WTV2_HUMAN" 5 941.4797 1.24 41927 5845 2 941.478737 471.7471 Proteasome activator complex subunit 3 OS=Homo sapiens OX=9606 GN=PSME3 PE=1 SV=1 4.14 1668 - 1.52E+06 - - - -1.0144 - 1.495 0.201 - 148 1 2 0 -0.001 8 0 0 0 5.89E+07 4.75E+07 - - - 1.7381 0.9975 221125_WJC_METTL3_EV_vs_WT_F04.05848.05848.2 0.34 12-Jun K.ITITNDK.G "sp|P54652|HSP72_HUMAN,sp|P0DMV8|HS71A_HUMAN,sp|P34931|HS71L_HUMAN,sp|P11142|HSP7C_HUMAN,sp|P0DMV9|HS71B_HUMAN,sp|P17066|HSP76_HUMAN,tr|E9PNE6|E9PNE6_HUMAN,tr|A8K7Q2|A8K7Q2_HUMAN,tr|E9PKE3|E9PKE3_HUMAN,tr|E9PM13|E9PM13_HUMAN,tr|E9PS65|E9PS65_HUMAN,tr|Q53FA3|Q53FA3_HUMAN,tr|V9GZ37|V9GZ37_HUMAN,tr|A0A0G2JIW1|A0A0G2JIW1_HUMAN" 14 803.4389 0.15 41928 5848 2 803.438976 402.7267 Heat shock-related 70 kDa protein 2 OS=Homo sapiens OX=9606 GN=HSPA2 PE=1 SV=1 5.84 1668.4 - 4.33E+07 - - - 0.1158 - 1.393 0.208 - 117 1 2 0 0.0001 7 0 0 0 7.83E+09 5.09E+10 - - - 1.6275 0.9997 221125_WJC_METTL3_EV_vs_WT_F04.05851.05851.2 0.00038 16-Aug K.VAGDC[160.03]LDEK.Q sp|Q96AG4|LRC59_HUMAN 1 1005.4437 1.47 41929 5851 2 1005.44232 503.7291 Leucine-rich repeat-containing protein 59 OS=Homo sapiens OX=9606 GN=LRRC59 PE=1 SV=1 4.03 1668.8 - 8.70E+06 - - - -1.3835 - 1.528 0.506 - 170.5 1 2 0 -0.0014 9 0 0 0 2.29E+08 1.56E+08 - - - 4.0044 0.9985 221125_WJC_METTL3_EV_vs_WT_F04.05852.05852.2 0.00571 14-Jul K.IVEMSTSK[136.11].T "sp|P63241|IF5A1_HUMAN,sp|Q9GZV4|IF5A2_HUMAN,tr|C9J4W5|C9J4W5_HUMAN,tr|I3L397|I3L397_HUMAN,tr|I3L504|I3L504_HUMAN,tr|C9J7B5|C9J7B5_HUMAN,tr|F8WCJ1|F8WCJ1_HUMAN" 7 901.467 0.96 41930 5852 2 901.464726 451.7408 Eukaryotic translation initiation factor 5A-1 OS=Homo sapiens OX=9606 GN=EIF5A PE=1 SV=2 6 1668.9 - 2.75E+06 - - - -2.5436 - 1.513 0.379 - 127.1 1 2 0 -0.0023 8 0 0 0 3.40E+08 3.53E+08 - - - 3.0885 0.9993 221125_WJC_METTL3_EV_vs_WT_F04.05856.05856.2 2.63E-05 16-Sep R.TATQLAVNK[136.11].L "sp|Q99832|TCPH_HUMAN,tr|F8WAM2|F8WAM2_HUMAN" 2 952.5433 0.2 41932 5856 2 952.541171 477.2789 T-complex protein 1 subunit eta OS=Homo sapiens OX=9606 GN=CCT7 PE=1 SV=2 8.41 1669.4 - 4.19E+06 - - - -2.2298 - 1.718 0.412 - 319.1 1 2 0 -0.0021 9 0 0 0 1.15E+08 5.88E+08 - - - 3.649 0.842 221125_WJC_METTL3_EV_vs_WT_F04.05860.05860.2 0.0866 20-Aug G.EAAGGPAQESR[166.11].Q sp|Q5M8T2|S35D3_HUMAN 1 1081.5028 1.35 41934 5860 2 1081.500775 541.7587 Solute carrier family 35 member D3 OS=Homo sapiens OX=9606 GN=SLC35D3 PE=2 SV=1 4.53 1669.9 - 234301 - - - -1.8456 - 1.439 0.263 - 205.5 1 1 0 -0.002 11 0 0 0 1.47E+07 1.09E+07 - - - 1.9675 0.9879 221125_WJC_METTL3_EV_vs_WT_F04.05865.05865.2 3.18 12-Jun R.TVDIEGK.K "sp|P51153|RAB13_HUMAN,sp|A1KZ92|PXDNL_HUMAN,tr|D6RB54|D6RB54_HUMAN" 3 760.3967 0.74 41936 5865 2 760.395695 381.2056 Ras-related protein Rab-13 OS=Homo sapiens OX=9606 GN=RAB13 PE=1 SV=1 4.37 1670.5 - 887728 - - - -1.3006 - 1.254 0.147 - 149.4 2 2 0 -0.001 7 0 0 0 3.42E+07 4.63E+07 - - - 0.7091 0.9986 221125_WJC_METTL3_EV_vs_WT_F04.05871.05871.2 0.00723 14-Aug R.ISEDVEER[166.11].L sp|P55081|MFAP1_HUMAN 1 985.4592 1.18 41938 5871 2 985.456481 493.7369 Microfibrillar-associated protein 1 OS=Homo sapiens OX=9606 GN=MFAP1 PE=1 SV=2 4 1671.4 - 721706 - - - -2.7338 - 1.874 0.324 - 195 1 2 0 -0.0027 8 0 0 0 1.19E+08 1.01E+08 - - - 3.3275 0.9614 221125_WJC_METTL3_EV_vs_WT_F04.05873.05873.2 0.39 14-Jun K.ASSLSTYK.L sp|Q9NRL2|BAZ1A_HUMAN 1 855.4338 1.23 41940 5873 2 855.432657 428.7242 Bromodomain adjacent to zinc finger domain protein 1A OS=Homo sapiens OX=9606 GN=BAZ1A PE=1 SV=2 8.63 1671.6 - 1.02E+06 - - - -1.3338 - 1.102 0.083 - 84.9 1 2 0 -0.0011 8 0 0 0 6.51E+07 5.29E+07 - - - -0.0534 0.9968 221125_WJC_METTL3_EV_vs_WT_F04.05875.05875.2 0.0407 16-Sep M.PYANQPTVR[166.11].L "sp|P19387|RPB3_HUMAN,tr|H3BRR2|H3BRR2_HUMAN" 2 1054.5435 0.93 41942 5875 2 1054.540827 528.279 DNA-directed RNA polymerase II subunit RPB3 OS=Homo sapiens OX=9606 GN=POLR2C PE=1 SV=2 9.18 1671.9 - 591053 - - - -2.5471 - 1.645 0.256 - 335.4 1 2 0 -0.0027 9 0 0 0 6.18E+07 6.67E+07 - - - 2.371 0.9989 221125_WJC_METTL3_EV_vs_WT_F04.05886.05886.2 0.0689 14-Sep R.VNAELQAR[166.11].S "sp|O95831|AIFM1_HUMAN,tr|A0A6Q8PFA7|A0A6Q8PFA7_HUMAN,tr|A0A6Q8PHJ9|A0A6Q8PHJ9_HUMAN,tr|A0A6Q8PFS4|A0A6Q8PFS4_HUMAN,tr|E9PMA0|E9PMA0_HUMAN,tr|A0A7I2PK44|A0A7I2PK44_HUMAN,tr|A0A6Q8PG15|A0A6Q8PG15_HUMAN,tr|A0A6Q8PFE1|A0A6Q8PFE1_HUMAN,tr|A0A7I2RLJ8|A0A7I2RLJ8_HUMAN,tr|A0A6Q8PFQ8|A0A6Q8PFQ8_HUMAN,tr|A0A6Q8PHC0|A0A6Q8PHC0_HUMAN,tr|A0A6Q8PFM5|A0A6Q8PFM5_HUMAN" 12 909.4907 0.75 41947 5886 2 909.489166 455.7527 "Apoptosis-inducing factor 1, mitochondrial OS=Homo sapiens OX=9606 GN=AIFM1 PE=1 SV=1" 5.97 1673.3 - 4.22E+06 - - - -1.7405 - 1.764 0.283 - 233.9 1 2 0 -0.0016 8 0 0 0 1.15E+08 1.54E+08 - - - 2.8425 0.9995 221125_WJC_METTL3_EV_vs_WT_F04.05887.05887.2 0.000329 18-Oct K.GEGQLGPAER[166.11].A sp|P13639|EF2_HUMAN 1 1022.502 0.55 41948 5887 2 1022.499628 512.2583 Elongation factor 2 OS=Homo sapiens OX=9606 GN=EEF2 PE=1 SV=4 4.53 1673.4 - 3.41E+06 - - - -2.3609 - 1.834 0.486 - 405.7 1 2 0 -0.0024 10 0 0 0 2.53E+08 4.56E+08 - - - 4.3228 0.9984 221125_WJC_METTL3_EV_vs_WT_F04.05901.05901.2 0.0165 14-Jul R.ISEDVEER.L sp|P55081|MFAP1_HUMAN 1 975.4509 1.18 41953 5901 2 975.448714 488.7327 Microfibrillar-associated protein 1 OS=Homo sapiens OX=9606 GN=MFAP1 PE=1 SV=2 4 1675.3 - 3.91E+06 - - - -2.2461 - 1.649 0.306 - 150.3 1 2 0 -0.0022 8 0 0 0 1.19E+08 1.01E+08 - - - 2.8089 0.999 221125_WJC_METTL3_EV_vs_WT_F04.05903.05903.2 0.0164 14-Oct K.TGEVLDTK.Y "sp|Q92520|FAM3C_HUMAN,tr|C9JMN4|C9JMN4_HUMAN,tr|C9JP35|C9JP35_HUMAN" 3 861.4444 1.17 41955 5903 2 861.441796 431.7295 Protein FAM3C OS=Homo sapiens OX=9606 GN=FAM3C PE=1 SV=1 4.37 1675.3 - 7.39E+06 - - - -2.9799 - 2.222 0.334 - 614.2 1 2 0 -0.0026 8 0 0 0 3.06E+08 2.62E+08 - - - 3.9151 0.9994 221125_WJC_METTL3_EV_vs_WT_F04.05904.05904.2 0.00178 18-Aug K.GEGQLGPAER.A sp|P13639|EF2_HUMAN 1 1012.4938 0.56 41956 5904 2 1012.491995 507.2542 Elongation factor 2 OS=Homo sapiens OX=9606 GN=EEF2 PE=1 SV=4 4.53 1675.4 - 3.50E+06 - - - -1.7551 - 1.692 0.392 - 250.9 1 2 0 -0.0018 10 0 0 0 2.53E+08 4.55E+08 - - - 3.4037 0.9993 221125_WJC_METTL3_EV_vs_WT_F04.05909.05909.2 0.000383 14-Aug R.QQIYAAEK[136.11].A sp|P15924|DESP_HUMAN 1 957.5011 8.41 41959 5909 2 957.501826 479.7578 Desmoplakin OS=Homo sapiens OX=9606 GN=DSP PE=1 SV=3 6 1676 - 778804 - - - 0.7624 - 1.58 0.338 - 271 1 2 0 0.0007 8 0 0 0 1.71E+08 2.03E+07 - - - 2.9168 0.9985 221125_WJC_METTL3_EV_vs_WT_F04.05911.05911.2 0.0338 16-Aug K.ELTDEEAER.L "sp|Q9Y266|NUDC_HUMAN,tr|A0A0A0MSS4|A0A0A0MSS4_HUMAN,tr|A0A0A0MSU9|A0A0A0MSU9_HUMAN" 3 1090.4778 1.87 41961 5911 2 1090.474865 546.2462 Nuclear migration protein nudC OS=Homo sapiens OX=9606 GN=NUDC PE=1 SV=1 3.91 1676.2 - 657943 - - - -2.7355 - 1.694 0.358 - 259.1 1 2 0 -0.003 9 0 0 0 6.02E+08 3.22E+08 - - - 3.2092 0.9982 221125_WJC_METTL3_EV_vs_WT_F04.05915.05915.2 0.0121 16-Sep K.ELTDEEAER[166.11].L "sp|Q9Y266|NUDC_HUMAN,tr|A0A0A0MSS4|A0A0A0MSS4_HUMAN,tr|A0A0A0MSU9|A0A0A0MSU9_HUMAN" 3 1100.4861 1.87 41963 5915 2 1100.482765 551.2503 Nuclear migration protein nudC OS=Homo sapiens OX=9606 GN=NUDC PE=1 SV=1 3.91 1676.7 - 739775 - - - -3.0468 - 1.723 0.363 - 380.2 1 2 0 -0.0034 9 0 0 0 6.02E+08 3.22E+08 - - - 3.2951 0.994 221125_WJC_METTL3_EV_vs_WT_F04.05917.05917.2 0.41 12-Jul R.LTESINR[166.11].D "sp|P25205|MCM3_HUMAN,tr|J3KQ69|J3KQ69_HUMAN,tr|A0A499FHX9|A0A499FHX9_HUMAN" 3 841.4533 0.19 41964 5917 2 841.450809 421.7339 DNA replication licensing factor MCM3 OS=Homo sapiens OX=9606 GN=MCM3 PE=1 SV=3 6 1677 - 4.95E+06 - - - -2.9615 - 1.436 0.258 - 170.5 1 2 0 -0.0025 7 0 0 0 5.63E+07 2.90E+08 - - - 2.0924 0.9689 221125_WJC_METTL3_EV_vs_WT_F04.05920.05920.2 0.0723 18-Oct K.AEEDAALQAK[136.11].K "sp|Q13428|TCOF_HUMAN,tr|E7ETY2|E7ETY2_HUMAN,tr|H0YA99|H0YA99_HUMAN,tr|H0Y8Y7|H0Y8Y7_HUMAN,tr|A0A3B3IS06|A0A3B3IS06_HUMAN,tr|A0A2R8Y857|A0A2R8Y857_HUMAN,tr|A0A2R8Y4M7|A0A2R8Y4M7_HUMAN" 7 1052.523 1.75 41965 5920 2 1052.515715 527.2688 Treacle protein OS=Homo sapiens OX=9606 GN=TCOF1 PE=1 SV=3 4.14 1677.4 - 1.78E+06 - - - -6.8778 - 1.626 0.368 - 323.4 1 2 0 -0.0072 10 0 0 0 6.26E+07 3.57E+07 - - - 3.1137 0.9879 221125_WJC_METTL3_EV_vs_WT_F04.05924.05924.2 0.0271 14-Aug K.IVEMSTSK.T "sp|P63241|IF5A1_HUMAN,sp|Q9GZV4|IF5A2_HUMAN,tr|C9J4W5|C9J4W5_HUMAN,tr|I3L397|I3L397_HUMAN,tr|I3L504|I3L504_HUMAN,tr|C9J7B5|C9J7B5_HUMAN,tr|F8WCJ1|F8WCJ1_HUMAN" 7 893.4528 0.95 41967 5924 2 893.450129 447.7337 Eukaryotic translation initiation factor 5A-1 OS=Homo sapiens OX=9606 GN=EIF5A PE=1 SV=2 6 1677.9 - 4.29E+06 - - - -3.0108 - 1.537 0.165 - 175.7 1 2 0 -0.0027 8 0 0 0 3.41E+08 3.59E+08 - - - 1.5552 0.9944 221125_WJC_METTL3_EV_vs_WT_F04.05927.05927.2 2.71 12-Jun K.NTVQGFK.R "sp|P34932|HSP74_HUMAN,tr|A0A087WTS8|A0A087WTS8_HUMAN,tr|A0A087WYC1|A0A087WYC1_HUMAN" 3 792.413 0.11 41968 5927 2 792.412389 397.2138 Heat shock 70 kDa protein 4 OS=Homo sapiens OX=9606 GN=HSPA4 PE=1 SV=4 8.75 1678.3 - 1.67E+06 - - - -0.7748 - 1.215 0.193 - 91.5 1 2 0 -0.0006 7 0 0 0 7.35E+07 6.44E+08 - - - 1.0834 0.9785 221125_WJC_METTL3_EV_vs_WT_F04.05929.05929.2 0.000796 12-Aug L.VGMPAK[136.11]R[166.11].Q "sp|P38646|GRP75_HUMAN,tr|H0Y8K0|H0Y8K0_HUMAN,tr|A0A7I2V2S7|A0A7I2V2S7_HUMAN,tr|A0A7I2V2G2|A0A7I2V2G2_HUMAN,tr|A0A3B3ITI4|A0A3B3ITI4_HUMAN,tr|A0A7I2V3F7|A0A7I2V3F7_HUMAN,tr|D6RCD7|D6RCD7_HUMAN" 7 775.4493 0.06 41969 5929 2 775.44797 388.732 "Stress-70 protein, mitochondrial OS=Homo sapiens OX=9606 GN=HSPA9 PE=1 SV=2" 11 1678.5 - 2.61E+06 - - - -1.7783 - 1.635 0.474 - 238.8 1 1 0 -0.0014 7 0 0 0 7.22E+06 1.13E+08 - - - 4.0993 0.9988 221125_WJC_METTL3_EV_vs_WT_F04.05931.05931.2 0.00437 16-Jul K.EIGSTMSGR[166.11].K "sp|O00422|SAP18_HUMAN,tr|H7BZW6|H7BZW6_HUMAN" 2 946.4417 1.16 41971 5931 2 946.440168 474.2282 Histone deacetylase complex subunit SAP18 OS=Homo sapiens OX=9606 GN=SAP18 PE=1 SV=1 6.1 1678.7 - 5.66E+06 - - - -1.6715 - 1.409 0.358 - 199.9 1 2 0 -0.0016 9 0 0 0 2.16E+08 1.86E+08 - - - 2.6767 0.9619 221125_WJC_METTL3_EV_vs_WT_F04.05932.05932.2 0.0263 12-May R.FENYGDK[136.11].F "sp|Q9BUJ2|HNRL1_HUMAN,tr|M0QYZ0|M0QYZ0_HUMAN,tr|A0A0A0MRA5|A0A0A0MRA5_HUMAN,tr|M0R3F1|M0R3F1_HUMAN,tr|B7Z4B8|B7Z4B8_HUMAN" 5 879.3854 1.55 41972 5932 2 879.382121 440.7 Heterogeneous nuclear ribonucleoprotein U-like protein 1 OS=Homo sapiens OX=9606 GN=HNRNPUL1 PE=1 SV=2 4.37 1678.7 - 906258 - - - -3.7265 - 1.186 0.203 - 59.8 1 2 0 -0.0033 7 0 0 0 1.60E+08 1.04E+08 - - - 1.0798 0.9979 221125_WJC_METTL3_EV_vs_WT_F04.05935.05935.2 0.0337 14-Sep K.TATITEPR.G sp|Q15029|U5S1_HUMAN 1 887.4712 1.47 41974 5935 2 887.468997 444.7429 116 kDa U5 small nuclear ribonucleoprotein component OS=Homo sapiens OX=9606 GN=EFTUD2 PE=1 SV=1 5.66 1679 - 4.20E+06 - - - -2.5342 - 1.473 0.341 - 438.1 1 2 0 -0.0022 8 0 0 0 4.19E+08 2.85E+08 - - - 2.727 0.9267 221125_WJC_METTL3_EV_vs_WT_F04.05943.05943.2 0.933 14-Jul K.SGYLAGDK[136.11].L sp|P26038|MOES_HUMAN 1 817.4061 0.82 41978 5943 2 817.403852 409.7103 Moesin OS=Homo sapiens OX=9606 GN=MSN PE=1 SV=3 5.55 1680 - 2.43E+06 - - - -2.7905 - 1.137 0.098 - 127.5 1 2 0 -0.0023 8 0 0 0 5.94E+07 7.26E+07 - - - 0.1513 0.9993 221125_WJC_METTL3_EV_vs_WT_F04.05945.05945.2 0.000784 16-Jul K.EIGSTMSGR.K "sp|O00422|SAP18_HUMAN,tr|H7BZW6|H7BZW6_HUMAN" 2 936.4335 1.17 41979 5945 2 936.432824 469.224 Histone deacetylase complex subunit SAP18 OS=Homo sapiens OX=9606 GN=SAP18 PE=1 SV=1 6.1 1680.2 - 9.01E+06 - - - -0.7005 - 1.304 0.405 - 169.4 1 2 0 -0.0007 9 0 0 0 2.15E+08 1.84E+08 - - - 2.8 0.9951 221125_WJC_METTL3_EV_vs_WT_F04.05952.05952.2 0.00334 12-Jul R.FENYGDK.F "sp|Q9BUJ2|HNRL1_HUMAN,tr|M0QYZ0|M0QYZ0_HUMAN,tr|A0A0A0MRA5|A0A0A0MRA5_HUMAN,tr|M0R3F1|M0R3F1_HUMAN,tr|B7Z4B8|B7Z4B8_HUMAN" 5 871.3712 1.55 41984 5952 2 871.370853 436.6929 Heterogeneous nuclear ribonucleoprotein U-like protein 1 OS=Homo sapiens OX=9606 GN=HNRNPUL1 PE=1 SV=2 4.37 1681 - 3.64E+06 - - - -0.3959 - 1.404 0.137 - 143.7 1 2 0 -0.0003 7 0 0 0 1.60E+08 1.04E+08 - - - 1.1279 0.9989 221125_WJC_METTL3_EV_vs_WT_F04.05959.05959.2 0.213 14-Jul R.EAYNQGLK.K sp|O94906|PRP6_HUMAN 1 921.4556 1.65 41989 5959 2 921.455436 461.7351 Pre-mRNA-processing factor 6 OS=Homo sapiens OX=9606 GN=PRPF6 PE=1 SV=1 6.1 1681.9 - 3.04E+06 - - - -0.1736 - 1.332 0.323 - 143.8 1 2 0 -0.0002 8 0 0 0 8.34E+07 5.04E+07 - - - 2.2912 0.9886 221125_WJC_METTL3_EV_vs_WT_F04.05962.05962.2 0.0781 14-May K.WVGC[160.03]QGSR[166.11].S "sp|Q6ZRP7|QSOX2_HUMAN,tr|H0Y430|H0Y430_HUMAN" 2 958.4319 1.56 41992 5962 2 958.432639 480.2232 Sulfhydryl oxidase 2 OS=Homo sapiens OX=9606 GN=QSOX2 PE=1 SV=3 8.25 1682.2 - 356831 - - - 0.818 - 1.15 0.181 - 97 2 2 0 0.0008 8 0 0 0 2.07E+07 1.33E+07 - - - 0.6647 0.9986 221125_WJC_METTL3_EV_vs_WT_F04.05968.05968.2 0.029 14-Jul K.FVETPGQK[136.11].Y "sp|P05455|LA_HUMAN,tr|E7ERC4|E7ERC4_HUMAN" 2 912.4796 0.92 41996 5968 2 912.478946 457.2471 Lupus La protein OS=Homo sapiens OX=9606 GN=SSB PE=1 SV=2 6 1683 - 741068 - - - -0.7518 - 1.431 0.278 - 136.5 1 2 0 -0.0007 8 0 0 0 8.60E+07 9.34E+07 - - - 2.1749 0.994 221125_WJC_METTL3_EV_vs_WT_F04.05975.05975.2 0.304 14-Jun K.EIEVGGGR.K "sp|P62081|RS7_HUMAN,tr|B5MCP9|B5MCP9_HUMAN" 2 815.4137 0.87 41999 5975 2 815.414312 408.7141 40S ribosomal protein S7 OS=Homo sapiens OX=9606 GN=RPS7 PE=1 SV=1 4.53 1683.8 - 6.52E+06 - - - 0.7125 - 1.147 0.221 - 96.2 1 2 0 0.0006 8 0 0 0 5.59E+08 6.42E+08 - - - 1.0868 0.9905 221125_WJC_METTL3_EV_vs_WT_F04.05980.05980.2 0.129 14-Jul R.SLEPGTPR[166.11].W "sp|P51570|GALK1_HUMAN,tr|K7ERJ9|K7ERJ9_HUMAN,tr|K7ERN9|K7ERN9_HUMAN,tr|K7EII7|K7EII7_HUMAN" 4 865.4533 1.59 42001 5980 2 865.449771 433.7339 Galactokinase OS=Homo sapiens OX=9606 GN=GALK1 PE=1 SV=1 5.72 1684.5 - 618989 - - - -4.0788 - 1.476 0.296 - 190.8 1 2 0 -0.0035 8 0 0 0 1.79E+08 1.12E+08 - - - 2.4004 0.9675 221125_WJC_METTL3_EV_vs_WT_F04.05984.05984.2 3.07 12-May K.QILSNPK[136.11].F "sp|Q9BXJ9|NAA15_HUMAN,tr|A0A0B4J1W3|A0A0B4J1W3_HUMAN" 2 806.4742 0.26 42003 5984 2 806.474594 404.2444 "N-alpha-acetyltransferase 15, NatA auxiliary subunit OS=Homo sapiens OX=9606 GN=NAA15 PE=1 SV=1" 8.75 1685 - 1.35E+06 - - - 0.5468 - 1.088 0.081 - 110.2 1 2 0 0.0004 7 0 0 0 1.10E+07 4.25E+07 - - - -0.0936 0.9993 221125_WJC_METTL3_EV_vs_WT_F04.05986.05986.2 0.0148 14-Sep R.LTSSLTTK[136.11].G "sp|P22695|QCR2_HUMAN,tr|H3BP04|H3BP04_HUMAN,tr|H3BUE4|H3BUE4_HUMAN,tr|H3BUI9|H3BUI9_HUMAN,tr|H3BRG4|H3BRG4_HUMAN,tr|H3BSJ9|H3BSJ9_HUMAN,tr|A0A087WVZ4|A0A087WVZ4_HUMAN" 7 857.4949 1.46 42005 5986 2 857.495835 429.7548 "Cytochrome b-c1 complex subunit 2, mitochondrial OS=Homo sapiens OX=9606 GN=UQCRC2 PE=1 SV=3" 8.75 1685.2 - 1.93E+06 - - - 1.0344 - 1.62 0.344 - 210.6 1 2 0 0.0009 8 0 0 0 8.72E+07 5.99E+07 - - - 3.0365 0.996 221125_WJC_METTL3_EV_vs_WT_F04.05988.05988.2 0.0369 16-Aug M.PYANQPTVR.L "sp|P19387|RPB3_HUMAN,tr|H3BRR2|H3BRR2_HUMAN" 2 1044.5352 0.92 42006 5988 2 1044.539557 523.2749 DNA-directed RNA polymerase II subunit RPB3 OS=Homo sapiens OX=9606 GN=POLR2C PE=1 SV=2 9.18 1685.4 - 661662 - - - 4.1301 - 1.877 0.331 - 300.1 1 2 0 0.0043 9 0 0 0 6.17E+07 6.67E+07 - - - 3.3061 0.9986 221125_WJC_METTL3_EV_vs_WT_F04.05990.05990.2 0.0388 14-Aug R.LTSSLTTK.G "sp|P22695|QCR2_HUMAN,tr|H3BP04|H3BP04_HUMAN,tr|H3BUE4|H3BUE4_HUMAN,tr|H3BUI9|H3BUI9_HUMAN,tr|H3BRG4|H3BRG4_HUMAN,tr|H3BSJ9|H3BSJ9_HUMAN,tr|A0A087WVZ4|A0A087WVZ4_HUMAN" 7 849.4807 1.46 42007 5990 2 849.480603 425.7477 "Cytochrome b-c1 complex subunit 2, mitochondrial OS=Homo sapiens OX=9606 GN=UQCRC2 PE=1 SV=3" 8.75 1685.6 - 2.57E+06 - - - -0.1707 - 1.581 0.227 - 175.2 1 2 0 -0.0001 8 0 0 0 8.74E+07 5.99E+07 - - - 2.0991 0.9995 221125_WJC_METTL3_EV_vs_WT_F04.05991.05991.2 0.000135 18-Oct R.TPATAPVPAR[166.11].A "sp|P18887|XRCC1_HUMAN,tr|F5H8D7|F5H8D7_HUMAN" 2 989.5534 1.12 42008 5991 2 989.553777 495.784 DNA repair protein XRCC1 OS=Homo sapiens OX=9606 GN=XRCC1 PE=1 SV=2 9.41 1685.7 - 928942 - - - 0.4315 - 2.205 0.24 - 448.7 1 2 0 0.0004 10 0 0 0 3.80E+07 3.40E+07 - - - 3.0207 0.9997 221125_WJC_METTL3_EV_vs_WT_F04.05996.05996.2 0.000366 18-Sep K.IINADSEDPK[136.11].Y "sp|P35998|PRS7_HUMAN,tr|C9JX88|C9JX88_HUMAN,tr|C9JLS9|C9JLS9_HUMAN" 3 1108.5492 2.03 42011 5996 2 1108.550887 555.2819 26S proteasome regulatory subunit 7 OS=Homo sapiens OX=9606 GN=PSMC2 PE=1 SV=3 4.03 1686.4 - 277673 - - - 1.5498 - 1.826 0.487 - 192.7 1 2 0 0.0017 10 0 0 0 5.63E+08 2.77E+08 - - - 4.3182 0.9997 221125_WJC_METTL3_EV_vs_WT_F04.05997.05997.2 0.00217 20-Aug R.LEQNGSPMGAR.G "sp|Q9UPW6|SATB2_HUMAN,tr|F8WCV6|F8WCV6_HUMAN,tr|C9JR56|C9JR56_HUMAN" 3 1158.5452 5.8 42012 5997 2 1158.543721 580.2799 DNA-binding protein SATB2 OS=Homo sapiens OX=9606 GN=SATB2 PE=1 SV=2 6 1686.5 - 186169 - - - -1.2386 - 1.749 0.471 - 198.5 1 2 0 -0.0014 11 0 0 0 9.66E+06 1.66E+06 - - - 4.0317 0.9998 221125_WJC_METTL3_EV_vs_WT_F04.05998.05998.2 0.000111 12-Aug K.C[160.03]GVISPR.F "sp|P62244|RS15A_HUMAN,tr|I3L3P7|I3L3P7_HUMAN,tr|H3BVC7|H3BVC7_HUMAN" 3 787.4011 0.41 42013 5998 2 787.401019 394.7078 40S ribosomal protein S15a OS=Homo sapiens OX=9606 GN=RPS15A PE=1 SV=2 8.25 1686.6 - 407947 - - - -0.0495 - 1.839 0.449 - 308.9 1 2 0 0 7 0 0 0 1.62E+07 3.94E+07 - - - 4.2877 0.9995 221125_WJC_METTL3_EV_vs_WT_F04.06002.06002.2 0.263 16-Oct R.TGVVTDGVK.H "sp|P38117|ETFB_HUMAN,tr|M0QY67|M0QY67_HUMAN" 2 874.476 1.39 42015 6002 2 874.477263 438.2453 Electron transfer flavoprotein subunit beta OS=Homo sapiens OX=9606 GN=ETFB PE=1 SV=3 5.5 1687.2 - 5.20E+06 - - - 1.4477 - 2.198 0.293 - 374.1 1 2 0 0.0013 9 0 0 0 2.37E+08 1.71E+08 - - - 3.4831 0.9968 221125_WJC_METTL3_EV_vs_WT_F04.06003.06003.2 0.707 14-Jun K.ALETVQER.K "sp|Q96QA5|GSDMA_HUMAN,tr|J3KRG2|J3KRG2_HUMAN" 2 944.4927 13.1 42016 6003 2 944.492438 473.2536 Gasdermin-A OS=Homo sapiens OX=9606 GN=GSDMA PE=1 SV=4 4.53 1687.2 - 1.19E+06 - - - -0.288 - 1.505 0.155 - 152.7 1 2 0 -0.0003 8 0 0 0 5.81E+07 4.44E+06 - - - 1.4186 0.996 221125_WJC_METTL3_EV_vs_WT_F04.06006.06006.2 0.12 16-Oct R.TVSLGAGAK.D "sp|P06748|NPM_HUMAN,tr|A0A7I2V4G8|A0A7I2V4G8_HUMAN,tr|A0A7I2YQC0|A0A7I2YQC0_HUMAN,tr|A0A7I2V433|A0A7I2V433_HUMAN,tr|A0A7I2V579|A0A7I2V579_HUMAN,tr|A0A7I2V2X9|A0A7I2V2X9_HUMAN,tr|A0A7I2V3G5|A0A7I2V3G5_HUMAN,tr|A0A7I2V5S2|A0A7I2V5S2_HUMAN,tr|A0A7I2V3U2|A0A7I2V3U2_HUMAN,tr|E5RGW4|E5RGW4_HUMAN" 10 802.4549 0.84 42017 6006 2 802.45697 402.2347 Nucleophosmin OS=Homo sapiens OX=9606 GN=NPM1 PE=1 SV=2 8.41 1687.6 - 2.11E+06 - - - 2.6195 - 1.748 0.217 - 250.5 1 2 0 0.0021 9 0 0 0 8.73E+08 1.04E+09 - - - 2.2588 0.9894 221125_WJC_METTL3_EV_vs_WT_F04.06007.06007.2 0.00473 12-Jul K.C[160.03]GVISPR[166.11].F "sp|P62244|RS15A_HUMAN,tr|I3L3P7|I3L3P7_HUMAN,tr|H3BVC7|H3BVC7_HUMAN" 3 797.4093 1.35 42018 6007 2 797.405462 399.7119 40S ribosomal protein S15a OS=Homo sapiens OX=9606 GN=RPS15A PE=1 SV=2 8.25 1687.7 - 1.24E+06 - - - -4.8482 - 1.421 0.36 - 230.2 1 2 0 -0.0039 7 0 0 0 5.39E+07 4.00E+07 - - - 2.8121 0.992 221125_WJC_METTL3_EV_vs_WT_F04.06013.06013.2 0.727 16-May R.VESLESQTR[166.11].Q "sp|O60271|JIP4_HUMAN,tr|A0A087X2D8|A0A087X2D8_HUMAN" 2 1057.5279 1 42022 6013 2 1057.527925 529.7712 C-Jun-amino-terminal kinase-interacting protein 4 OS=Homo sapiens OX=9606 GN=SPAG9 PE=1 SV=4 4.53 1688.4 - 161590 - - - 0.0019 - 1.177 0.189 - 53.4 2 2 0 0 9 0 0 0 7.79E+06 7.81E+06 - - - 0.774 0.966 221125_WJC_METTL3_EV_vs_WT_F04.06020.06020.2 0.862 12-Aug K.SIAIENK[136.11].E sp|Q9Y2X9|ZN281_HUMAN 1 781.4425 5.55 42025 6020 2 781.44188 391.7285 Zinc finger protein 281 OS=Homo sapiens OX=9606 GN=ZNF281 PE=1 SV=1 5.72 1689.3 - 1.63E+06 - - - -0.8177 - 1.177 0.044 - 208.8 1 2 0 -0.0006 7 0 0 0 6.09E+08 1.10E+08 - - - -0.1178 0.967 221125_WJC_METTL3_EV_vs_WT_F04.06025.06025.2 0.294 16-Aug R.SLVASAQQR.Q sp|Q96A37|RN166_HUMAN 1 958.5196 1.45 42027 6025 2 958.52268 480.2671 E3 ubiquitin-protein ligase RNF166 OS=Homo sapiens OX=9606 GN=RNF166 PE=1 SV=1 9.47 1690 - 197011 - - - 3.2206 - 1.463 0.108 - 185.8 1 2 0 0.0031 9 0 0 0 7.51E+06 5.17E+06 - - - 0.9385 0.9994 221125_WJC_METTL3_EV_vs_WT_F04.06026.06026.2 0.0085 18-Sep K.IINADSEDPK.Y "sp|P35998|PRS7_HUMAN,tr|C9JX88|C9JX88_HUMAN,tr|C9JLS9|C9JLS9_HUMAN" 3 1100.535 2.03 42028 6026 2 1100.535807 551.2748 26S proteasome regulatory subunit 7 OS=Homo sapiens OX=9606 GN=PSMC2 PE=1 SV=3 4.03 1690.1 - 815702 - - - 0.7614 - 1.732 0.322 - 196.8 1 2 0 0.0008 10 0 0 0 5.63E+08 2.77E+08 - - - 2.9522 0.9762 221125_WJC_METTL3_EV_vs_WT_F04.06033.06033.2 1.73E-05 18-Aug A.AAGFDSASAR[166.11].W "sp|O14654|IRS4_HUMAN,tr|A0A804CF45|A0A804CF45_HUMAN" 2 961.4493 0.63 42030 6033 2 961.449735 481.7319 Insulin receptor substrate 4 OS=Homo sapiens OX=9606 GN=IRS4 PE=1 SV=1 5.88 1691.1 - 116281 - - - 0.4743 - 1.59 0.405 - 182.4 1 1 0 0.0005 10 0 0 0 1.08E+07 1.70E+07 - - - 3.3266 0.9994 221125_WJC_METTL3_EV_vs_WT_F04.06034.06034.2 0.00478 16-Jul R.LEYGDNAEK[136.11].Y "sp|Q9Y224|RTRAF_HUMAN,tr|G3V4C6|G3V4C6_HUMAN,tr|H0YJB9|H0YJB9_HUMAN" 3 1045.4808 1.31 42031 6034 2 1045.481118 523.7477 "RNA transcription, translation and transport factor protein OS=Homo sapiens OX=9606 GN=RTRAF PE=1 SV=1" 4.14 1691.2 - 288243 - - - 0.3472 - 1.276 0.42 - 136.7 1 2 0 0.0004 9 0 0 0 1.98E+08 1.51E+08 - - - 2.8481 0.9996 221125_WJC_METTL3_EV_vs_WT_F04.06039.06039.2 0.00159 12-Jul K.TGIYEEK[136.11].H "sp|P27824|CALX_HUMAN,tr|A0A7P0T937|A0A7P0T937_HUMAN,tr|A0A7P0T840|A0A7P0T840_HUMAN,tr|D6RFL1|D6RFL1_HUMAN,tr|A0A7P0Z4H2|A0A7P0Z4H2_HUMAN,tr|A0A7P0TB65|A0A7P0TB65_HUMAN,tr|A0A7P0TAE9|A0A7P0TAE9_HUMAN,tr|D6RGY2|D6RGY2_HUMAN,tr|A0A7P0T8G1|A0A7P0T8G1_HUMAN,tr|A0A7P0Z4D6|A0A7P0Z4D6_HUMAN,tr|A0A7P0Z484|A0A7P0Z484_HUMAN,tr|A0A7P0TAR9|A0A7P0TAR9_HUMAN,tr|A0A7P0T9L0|A0A7P0T9L0_HUMAN" 13 846.4214 1.21 42034 6039 2 846.420906 424.218 Calnexin OS=Homo sapiens OX=9606 GN=CANX PE=1 SV=2 4.53 1691.8 - 1.78E+06 - - - -0.6415 - 1.56 0.388 - 190.8 1 2 0 -0.0005 7 0 0 0 1.32E+08 1.09E+08 - - - 3.3156 0.9993 221125_WJC_METTL3_EV_vs_WT_F04.06040.06040.2 0.0594 16-Sep R.LEYGDNAEK.Y "sp|Q9Y224|RTRAF_HUMAN,tr|G3V4C6|G3V4C6_HUMAN,tr|H0YJB9|H0YJB9_HUMAN" 3 1037.4666 1.31 42035 6040 2 1037.466638 519.7406 "RNA transcription, translation and transport factor protein OS=Homo sapiens OX=9606 GN=RTRAF PE=1 SV=1" 4.14 1692 - 533289 - - - 0.08 - 1.495 0.335 - 250.5 1 2 0 0.0001 9 0 0 0 1.98E+08 1.51E+08 - - - 2.6787 0.9961 221125_WJC_METTL3_EV_vs_WT_F04.06042.06042.2 0.458 14-Jul K.EIEVGGGR[166.11].K "sp|P62081|RS7_HUMAN,tr|B5MCP9|B5MCP9_HUMAN" 2 825.422 0.87 42036 6042 2 825.422044 413.7183 40S ribosomal protein S7 OS=Homo sapiens OX=9606 GN=RPS7 PE=1 SV=1 4.53 1692.2 - 1.29E+07 - - - 0.0521 - 1.218 0.224 - 184.8 1 2 0 0 8 0 0 0 5.59E+08 6.42E+08 - - - 1.2902 0.9991 221125_WJC_METTL3_EV_vs_WT_F04.06044.06044.2 0.0329 12-Aug K.C[160.03]DLEDER[166.11].V "sp|A6NIZ1|RP1BL_HUMAN,sp|P62834|RAP1A_HUMAN,sp|P61224|RAP1B_HUMAN,sp|O95716|RAB3D_HUMAN,tr|F5H7Y6|F5H7Y6_HUMAN,tr|E7ESV4|E7ESV4_HUMAN,tr|F5GX62|F5GX62_HUMAN,tr|A0A075B6Q0|A0A075B6Q0_HUMAN,tr|F5H004|F5H004_HUMAN,tr|B7ZB78|B7ZB78_HUMAN,tr|F5GZG1|F5GZG1_HUMAN,tr|F5H823|F5H823_HUMAN" 12 945.3737 1.09 42037 6044 2 945.375259 473.6941 Ras-related protein Rap-1b-like protein OS=Homo sapiens OX=9606 PE=2 SV=1 3.92 1692.4 - 1.84E+06 - - - 1.6163 - 1.631 0.334 - 312.3 1 2 0 0.0015 7 0 0 0 3.99E+07 3.65E+07 - - - 3.0575 0.9996 221125_WJC_METTL3_EV_vs_WT_F04.06046.06046.2 0.0107 12-Aug K.TGIYEEK.H "sp|P27824|CALX_HUMAN,tr|A0A7P0T937|A0A7P0T937_HUMAN,tr|A0A7P0T840|A0A7P0T840_HUMAN,tr|D6RFL1|D6RFL1_HUMAN,tr|A0A7P0Z4H2|A0A7P0Z4H2_HUMAN,tr|A0A7P0TB65|A0A7P0TB65_HUMAN,tr|A0A7P0TAE9|A0A7P0TAE9_HUMAN,tr|D6RGY2|D6RGY2_HUMAN,tr|A0A7P0T8G1|A0A7P0T8G1_HUMAN,tr|A0A7P0Z4D6|A0A7P0Z4D6_HUMAN,tr|A0A7P0Z484|A0A7P0Z484_HUMAN,tr|A0A7P0TAR9|A0A7P0TAR9_HUMAN,tr|A0A7P0T9L0|A0A7P0T9L0_HUMAN" 13 838.4072 1.2 42039 6046 2 838.407167 420.2109 Calnexin OS=Homo sapiens OX=9606 GN=CANX PE=1 SV=2 4.53 1692.6 - 2.60E+06 - - - -0.0978 - 1.585 0.369 - 246.5 1 2 0 -0.0001 7 0 0 0 1.33E+08 1.10E+08 - - - 3.2258 0.9958 221125_WJC_METTL3_EV_vs_WT_F04.06050.06050.2 0.173 14-Jul R.TANEIYEK.V sp|Q5W0B1|OBI1_HUMAN 1 966.4658 1.08 42041 6050 2 966.467619 484.2402 ORC ubiquitin ligase 1 OS=Homo sapiens OX=9606 GN=OBI1 PE=1 SV=1 4.53 1693.1 - 486718 - - - 1.8552 - 1.275 0.273 - 157.3 1 2 0 0.0018 8 0 0 0 3.61E+07 3.34E+07 - - - 1.7895 0.9979 221125_WJC_METTL3_EV_vs_WT_F04.06055.06055.2 0.00837 18-Jul R.VLADPSDDTK.G "sp|P58107|EPIPL_HUMAN,sp|P58107|EPIPL_HUMAN,sp|Q15149|PLEC_HUMAN,tr|A0A075B730|A0A075B730_HUMAN,tr|A0A075B730|A0A075B730_HUMAN,tr|H0YDN1|H0YDN1_HUMAN" 6 1059.5084 1.88 42044 6055 2 1059.509097 530.7615 Epiplakin OS=Homo sapiens OX=9606 GN=EPPK1 PE=1 SV=3 3.93 1693.8 - 257369 - - - 0.639 - 1.193 0.314 - 143.5 1 2 0 0.0007 10 0 0 0 6.51E+08 3.47E+08 - - - 1.8526 0.998 221125_WJC_METTL3_EV_vs_WT_F04.06056.06056.2 0.00725 14-Sep R.TANEIYEK[136.11].V sp|Q5W0B1|OBI1_HUMAN 1 974.48 1.4 42045 6056 2 974.481636 488.2473 ORC ubiquitin ligase 1 OS=Homo sapiens OX=9606 GN=OBI1 PE=1 SV=1 4.53 1693.9 - 582745 - - - 1.6522 - 1.544 0.263 - 274.3 1 2 0 0.0016 8 0 0 0 4.77E+07 3.41E+07 - - - 2.2931 0.9791 221125_WJC_METTL3_EV_vs_WT_F04.06062.06062.2 0.527 12-Jul K.NADELVK[136.11].Q "sp|P17987|TCPA_HUMAN,tr|F5H726|F5H726_HUMAN,tr|F5H136|F5H136_HUMAN,tr|E7ERF2|E7ERF2_HUMAN,tr|F5H676|F5H676_HUMAN" 5 795.4218 0.55 42049 6062 2 795.422639 398.7182 T-complex protein 1 subunit alpha OS=Homo sapiens OX=9606 GN=TCP1 PE=1 SV=1 4.37 1694.6 - 670080 - - - 1.0762 - 1.32 0.056 - 196 1 2 0 0.0009 7 0 0 0 1.17E+08 2.12E+08 - - - 0.334 0.9998 221125_WJC_METTL3_EV_vs_WT_F04.06063.06063.2 0.00088 18-Oct K.VNSLGETAER[166.11].L "sp|Q13813|SPTN1_HUMAN,tr|A0A0D9SF54|A0A0D9SF54_HUMAN,tr|A0A0D9SGF6|A0A0D9SGF6_HUMAN" 3 1084.5388 1.6 42050 6063 2 1084.538879 543.2767 "Spectrin alpha chain, non-erythrocytic 1 OS=Homo sapiens OX=9606 GN=SPTAN1 PE=1 SV=3" 4.53 1694.7 - 330273 - - - 0.0526 - 2.15 0.394 - 392.3 1 2 0 0.0001 10 0 0 0 7.13E+07 4.45E+07 - - - 4.0877 0.9972 221125_WJC_METTL3_EV_vs_WT_F04.06067.06067.2 0.0557 14-Aug R.VSIAPSQR.Q sp|O43395|PRPF3_HUMAN 1 856.4767 1.99 42052 6067 2 856.47512 429.2456 U4\U6 small nuclear ribonucleoprotein Prp3 OS=Homo sapiens OX=9606 GN=PRPF3 PE=1 SV=2 9.72 1695.3 - 4.02E+06 - - - -1.8051 - 1.411 0.265 - 220.9 1 2 0 -0.0015 8 0 0 0 9.54E+08 4.79E+08 - - - 2.0362 0.9727 221125_WJC_METTL3_EV_vs_WT_F04.06068.06068.2 0.338 14-Aug R.VSIAPSQR[166.11].Q sp|O43395|PRPF3_HUMAN 1 866.4849 2.14 42053 6068 2 866.486109 434.2497 U4\U6 small nuclear ribonucleoprotein Prp3 OS=Homo sapiens OX=9606 GN=PRPF3 PE=1 SV=2 9.72 1695.3 - 2.85E+06 - - - 1.3537 - 1.408 0.024 - 204.2 1 2 0 0.0012 8 0 0 0 9.45E+08 4.42E+08 - - - 0.2499 0.9968 221125_WJC_METTL3_EV_vs_WT_F04.06069.06069.2 0.0591 14-May R.SMMSSYER.S "sp|P18583|SON_HUMAN,tr|H7C1M2|H7C1M2_HUMAN" 2 989.3947 1.35 42054 6069 2 989.394304 495.7046 Protein SON OS=Homo sapiens OX=9606 GN=SON PE=1 SV=4 5.72 1695.4 - 1.47E+06 - - - -0.3517 - 0.916 0.359 - 71 1 2 0 -0.0003 8 0 0 0 6.56E+07 4.86E+07 - - - 1.4278 0.9998 221125_WJC_METTL3_EV_vs_WT_F04.06070.06070.2 0.000628 18-Oct K.VNSLGETAER.L "sp|Q13813|SPTN1_HUMAN,tr|A0A0D9SF54|A0A0D9SF54_HUMAN,tr|A0A0D9SGF6|A0A0D9SGF6_HUMAN" 3 1074.5306 1.34 42055 6070 2 1074.531099 538.2726 "Spectrin alpha chain, non-erythrocytic 1 OS=Homo sapiens OX=9606 GN=SPTAN1 PE=1 SV=3" 4.53 1695.5 - 621557 - - - 0.5091 - 2.176 0.431 - 339.7 1 2 0 0.0005 10 0 0 0 7.13E+07 5.31E+07 - - - 4.3944 0.9983 221125_WJC_METTL3_EV_vs_WT_F04.06073.06073.2 0.00262 16-Jul R.YDDMASAMK.A "sp|Q04917|1433F_HUMAN,tr|A2IDB1|A2IDB1_HUMAN,tr|F8WEB6|F8WEB6_HUMAN" 3 1030.41 1.15 42056 6073 2 1030.410558 516.2123 14-3-3 protein eta OS=Homo sapiens OX=9606 GN=YWHAH PE=1 SV=4 4.21 1696 - 947269 - - - 0.5726 - 1.265 0.308 - 98 1 2 0 0.0006 9 0 0 0 7.52E+07 6.52E+07 - - - 1.9958 0.9953 221125_WJC_METTL3_EV_vs_WT_F04.06074.06074.2 0.103 18-May R.VLADPSDDTK[136.11].G "sp|P58107|EPIPL_HUMAN,sp|P58107|EPIPL_HUMAN,sp|Q15149|PLEC_HUMAN,tr|A0A075B730|A0A075B730_HUMAN,tr|A0A075B730|A0A075B730_HUMAN,tr|H0YDN1|H0YDN1_HUMAN" 6 1067.5226 1.88 42057 6074 2 1067.52233 534.7686 Epiplakin OS=Homo sapiens OX=9606 GN=EPPK1 PE=1 SV=3 3.93 1696.1 - 263180 - - - -0.2717 - 1.03 0.291 - 70 2 2 0 -0.0003 10 0 0 0 6.53E+08 3.47E+08 - - - 1.1383 0.9982 221125_WJC_METTL3_EV_vs_WT_F04.06075.06075.2 0.076 12-May R.NGPEFEK.M "sp|Q8IWX8|CHERP_HUMAN,tr|J3QK89|J3QK89_HUMAN" 2 819.3763 1.35 42058 6075 2 819.376029 410.6954 Calcium homeostasis endoplasmic reticulum protein OS=Homo sapiens OX=9606 GN=CHERP PE=1 SV=3 4.53 1696.2 - 2.14E+06 - - - -0.31 - 1.126 0.332 - 106 1 2 0 -0.0003 7 0 0 0 7.05E+07 5.22E+07 - - - 1.8691 0.999 221125_WJC_METTL3_EV_vs_WT_F04.06077.06077.2 0.000585 14-Aug R.SDLYSSGR[166.11].D "sp|P38159|RBMX_HUMAN,tr|H3BUY5|H3BUY5_HUMAN" 2 893.4118 1.43 42059 6077 2 893.411353 447.7132 "RNA-binding motif protein, X chromosome OS=Homo sapiens OX=9606 GN=RBMX PE=1 SV=3" 5.55 1696.4 - 3.56E+07 - - - -0.5339 - 1.739 0.228 - 274.1 1 2 0 -0.0005 8 0 0 0 1.59E+09 1.11E+09 - - - 2.3936 0.9996 221125_WJC_METTL3_EV_vs_WT_F04.06079.06079.2 0.0534 12-Jul K.C[160.03]DLEDER.V "sp|A6NIZ1|RP1BL_HUMAN,sp|P62834|RAP1A_HUMAN,sp|P61224|RAP1B_HUMAN,sp|O95716|RAB3D_HUMAN,tr|F5H7Y6|F5H7Y6_HUMAN,tr|E7ESV4|E7ESV4_HUMAN,tr|F5GX62|F5GX62_HUMAN,tr|A0A075B6Q0|A0A075B6Q0_HUMAN,tr|F5H004|F5H004_HUMAN,tr|B7ZB78|B7ZB78_HUMAN,tr|F5GZG1|F5GZG1_HUMAN,tr|F5H823|F5H823_HUMAN" 12 935.3655 1.09 42060 6079 2 935.365152 468.69 Ras-related protein Rap-1b-like protein OS=Homo sapiens OX=9606 PE=2 SV=1 3.92 1696.6 - 1.14E+06 - - - -0.3304 - 1.578 0.391 - 323.8 1 2 0 -0.0003 7 0 0 0 3.99E+07 3.65E+07 - - - 3.3742 0.9991 221125_WJC_METTL3_EV_vs_WT_F04.06086.06086.2 0.0011 18-Sep K.ENGAAALDGR[166.11].L "sp|P57105|SYJ2B_HUMAN,tr|A0A087X1F5|A0A087X1F5_HUMAN,tr|A0A087WYV9|A0A087WYV9_HUMAN" 3 982.4707 1.1 42063 6086 2 982.473716 492.2426 Synaptojanin-2-binding protein OS=Homo sapiens OX=9606 GN=SYNJ2BP PE=1 SV=2 4.37 1697.5 - 227610 - - - 3.0271 - 1.984 0.431 - 388.2 1 2 0 0.003 10 0 0 0 2.20E+07 1.99E+07 - - - 4.1358 0.9976 221125_WJC_METTL3_EV_vs_WT_F04.06090.06090.2 0.00475 22-May K.VGGTSDVEVNEK.K "sp|P10809|CH60_HUMAN,tr|A0A7I2V2X6|A0A7I2V2X6_HUMAN,tr|A0A7I2YQK6|A0A7I2YQK6_HUMAN,tr|A0A7I2V599|A0A7I2V599_HUMAN" 4 1232.5885 1.19 42064 6090 2 1232.588419 617.3015 "60 kDa heat shock protein, mitochondrial OS=Homo sapiens OX=9606 GN=HSPD1 PE=1 SV=2" 4.14 1698.1 - 136138 - - - -0.0341 - 1.427 0.262 - 31.2 4 2 0 0 12 0 0 0 1.80E+07 1.51E+07 - - - 1.6428 0.9996 221125_WJC_METTL3_EV_vs_WT_F04.06092.06092.2 0.00142 16-Dec K.QEAADAALR.V "sp|P55265|DSRAD_HUMAN,tr|A0A3B3IRQ9|A0A3B3IRQ9_HUMAN,tr|A0A3B3ISU1|A0A3B3ISU1_HUMAN,tr|A0A7P0Z4K3|A0A7P0Z4K3_HUMAN,tr|A0A7P0Z4F9|A0A7P0Z4F9_HUMAN" 5 943.4723 0.77 42065 6092 2 943.470245 472.7434 Double-stranded RNA-specific adenosine deaminase OS=Homo sapiens OX=9606 GN=ADAR PE=1 SV=4 4.37 1698.3 - 3.92E+06 - - - -2.1877 - 2.419 0.387 - 868.4 1 2 0 -0.0021 9 0 0 0 1.35E+08 1.74E+08 - - - 4.4543 0.9999 221125_WJC_METTL3_EV_vs_WT_F04.06094.06094.2 7.80E-07 22-Sep K.VGGTSDVEVNEK[136.11].K "sp|P10809|CH60_HUMAN,tr|A0A7I2V2X6|A0A7I2V2X6_HUMAN,tr|A0A7I2YQK6|A0A7I2YQK6_HUMAN,tr|A0A7I2V599|A0A7I2V599_HUMAN" 4 1240.6027 1.19 42067 6094 2 1240.602041 621.3086 "60 kDa heat shock protein, mitochondrial OS=Homo sapiens OX=9606 GN=HSPD1 PE=1 SV=2" 4.14 1698.6 - 165711 - - - -0.4998 - 2.181 0.568 - 327.3 1 2 0 -0.0006 12 0 0 0 1.80E+07 1.51E+07 - - - 5.2878 0.9965 221125_WJC_METTL3_EV_vs_WT_F04.06099.06099.2 0.0948 14-Jul R.TLIENGEK.L "sp|P37198|NUP62_HUMAN,tr|M0QXN5|M0QXN5_HUMAN" 2 902.4709 1.93 42069 6099 2 902.470757 452.2427 Nuclear pore glycoprotein p62 OS=Homo sapiens OX=9606 GN=NUP62 PE=1 SV=3 4.53 1699.2 - 1.73E+07 - - - -0.1718 - 1.395 0.177 - 154 1 2 0 -0.0002 8 0 0 0 5.40E+08 2.80E+08 - - - 1.3523 0.9986 221125_WJC_METTL3_EV_vs_WT_F04.06101.06101.2 0.564 14-Aug R.LLEEEDSK[136.11].L "sp|Q96CT7|CC124_HUMAN,tr|M0R2F5|M0R2F5_HUMAN" 2 969.4746 0.92 42070 6101 2 969.474594 485.7446 Coiled-coil domain-containing protein 124 OS=Homo sapiens OX=9606 GN=CCDC124 PE=1 SV=1 4 1699.4 - 1.00E+06 - - - -0.0134 - 1.381 0.277 - 178.7 1 2 0 0 8 0 0 0 1.10E+08 1.19E+08 - - - 2.0605 0.9998 221125_WJC_METTL3_EV_vs_WT_F04.06103.06103.2 0.00178 14-Sep R.MGANNLER.M "sp|P52272|HNRPM_HUMAN,tr|M0R2I7|M0R2I7_HUMAN,tr|A0A087X0X3|A0A087X0X3_HUMAN,tr|M0QZM1|M0QZM1_HUMAN" 4 903.4233 1.68 42071 6103 2 903.423423 452.7189 Heterogeneous nuclear ribonucleoprotein M OS=Homo sapiens OX=9606 GN=HNRNPM PE=1 SV=3 5.75 1699.6 - 1.75E+07 - - - 0.1915 - 1.656 0.457 - 249.2 1 2 0 0.0002 8 0 0 0 6.93E+08 4.13E+08 - - - 3.9376 0.9918 221125_WJC_METTL3_EV_vs_WT_F04.06111.06111.2 0.0821 12-Jun R.DYAPPPR.D "sp|Q96E39|RMXL1_HUMAN,sp|P38159|RBMX_HUMAN,tr|H3BUY5|H3BUY5_HUMAN,tr|H3BT71|H3BT71_HUMAN,tr|H0Y6E7|H0Y6E7_HUMAN" 5 814.3974 0.7 42075 6111 2 814.3949 408.206 "RNA binding motif protein, X-linked-like-1 OS=Homo sapiens OX=9606 GN=RBMXL1 PE=1 SV=1" 5.84 1700.6 - 2.79E+06 - - - -3.012 - 1.391 0.241 - 172.8 1 2 0 -0.0025 7 0 0 0 2.14E+08 3.04E+08 - - - 1.866 0.9993 221125_WJC_METTL3_EV_vs_WT_F04.06112.06112.2 0.0183 14-Aug K.APGFGDNR[166.11].K "sp|P10809|CH60_HUMAN,tr|A0A7I2V2X6|A0A7I2V2X6_HUMAN,tr|A0A7I2YQK6|A0A7I2YQK6_HUMAN,tr|A0A7I2V599|A0A7I2V599_HUMAN,tr|A0A7I2V5M1|A0A7I2V5M1_HUMAN" 5 842.391 1.32 42076 6112 2 842.390508 422.2028 "60 kDa heat shock protein, mitochondrial OS=Homo sapiens OX=9606 GN=HSPD1 PE=1 SV=2" 5.88 1700.6 - 1.20E+06 - - - -0.6256 - 1.496 0.338 - 230 1 2 0 -0.0005 8 0 0 0 1.12E+10 8.46E+09 - - - 2.7521 0.9994 221125_WJC_METTL3_EV_vs_WT_F04.06116.06116.2 0.0387 14-Jul K.ELQEQMSR.G "sp|Q7L1Q6|BZW1_HUMAN,tr|C9IZ80|C9IZ80_HUMAN,tr|H0Y503|H0Y503_HUMAN" 3 1019.4706 1.03 42078 6116 2 1019.470708 510.7426 Basic leucine zipper and W2 domain-containing protein 1 OS=Homo sapiens OX=9606 GN=BZW1 PE=1 SV=1 4.53 1701.2 - 290614 - - - 0.1118 - 1.429 0.378 - 156.3 1 2 0 0.0001 8 0 0 0 1.74E+07 1.69E+07 - - - 2.9095 0.9977 221125_WJC_METTL3_EV_vs_WT_F04.06121.06121.2 0.00906 16-Jun K.DVDSAYMNK.V sp|P12035|K2C3_HUMAN 1 1041.4437 1250.09 42081 6121 2 1041.443769 521.7291 "Keratin, type II cytoskeletal 3 OS=Homo sapiens OX=9606 GN=KRT3 PE=1 SV=3" 4.21 1701.7 - 3.67E+06 - - - 0.0557 - 1.18 0.292 - 76.7 1 2 0 0.0001 9 0 0 0 1.24E+08 9.90E+04 - - - 1.6765 0.9978 221125_WJC_METTL3_EV_vs_WT_F04.06131.06131.2 0.0133 14-Jul K.APGFGDNR.K "sp|P10809|CH60_HUMAN,tr|A0A7I2V2X6|A0A7I2V2X6_HUMAN,tr|A0A7I2YQK6|A0A7I2YQK6_HUMAN,tr|A0A7I2V599|A0A7I2V599_HUMAN,tr|A0A7I2V5M1|A0A7I2V5M1_HUMAN" 5 832.3828 1.32 42086 6131 2 832.382703 417.1987 "60 kDa heat shock protein, mitochondrial OS=Homo sapiens OX=9606 GN=HSPD1 PE=1 SV=2" 5.88 1702.8 - 7.13E+06 - - - -0.0745 - 1.281 0.258 - 169.6 1 2 0 -0.0001 8 0 0 0 1.12E+10 8.46E+09 - - - 1.6934 0.9932 221125_WJC_METTL3_EV_vs_WT_F04.06132.06132.2 0.271 14-Aug R.GGADVNIR.H sp|P08621|RU17_HUMAN 1 800.4141 1.58 42087 6132 2 800.414067 401.2143 U1 small nuclear ribonucleoprotein 70 kDa OS=Homo sapiens OX=9606 GN=SNRNP70 PE=1 SV=2 5.84 1702.8 - 2.74E+06 - - - 0.0012 - 1.29 0.146 - 214.4 1 2 0 0 8 0 0 0 8.94E+07 5.66E+07 - - - 0.8873 0.9994 221125_WJC_METTL3_EV_vs_WT_F04.06133.06133.2 0.00836 18-Sep R.ANTVTPAVGR.L sp|Q53HL2|BOREA_HUMAN 1 984.5352 1.86 42088 6133 2 984.535627 493.2749 Borealin OS=Homo sapiens OX=9606 GN=CDCA8 PE=1 SV=2 9.79 1703 - 485655 - - - 0.39 - 1.912 0.27 - 375.6 1 2 0 0.0004 10 0 0 0 1.51E+08 8.13E+07 - - - 2.8443 0.9988 221125_WJC_METTL3_EV_vs_WT_F04.06136.06136.2 0.552 12-Aug R.SNVVITR.M sp|Q86UP2|KTN1_HUMAN 1 787.4552 1.49 42089 6136 2 787.454172 394.7349 Kinectin OS=Homo sapiens OX=9606 GN=KTN1 PE=1 SV=1 9.47 1703.4 - 2.30E+06 - - - -1.308 - 1.794 0.22 - 438.8 1 2 0 -0.001 7 0 0 0 7.56E+07 5.06E+07 - - - 2.5175 0.9951 221125_WJC_METTL3_EV_vs_WT_F04.06137.06137.2 0.223 14-Aug K.SAVLQEAR.V "sp|Q9Y678|COPG1_HUMAN,sp|Q9UBF2|COPG2_HUMAN" 2 872.4716 0.48 42090 6137 2 872.470906 437.2431 Coatomer subunit gamma-1 OS=Homo sapiens OX=9606 GN=COPG1 PE=1 SV=1 5.72 1703.4 - 447932 - - - -0.7725 - 1.538 0.115 - 188.8 1 2 0 -0.0007 8 0 0 0 3.37E+07 7.07E+07 - - - 1.1885 0.9881 221125_WJC_METTL3_EV_vs_WT_F04.06142.06142.2 0.344 24-Jul R.LVGATATSSPPPK.A "sp|Q96QD9|UIF_HUMAN,tr|H9KVD1|H9KVD1_HUMAN" 2 1224.6714 1.15 42092 6142 2 1224.673419 613.343 UAP56-interacting factor OS=Homo sapiens OX=9606 GN=FYTTD1 PE=1 SV=3 8.75 1704.2 - 73903.1 - - - 1.6462 - 1.236 0.182 - 136.2 1 2 0 0.002 13 0 0 0 4.01E+06 3.48E+06 - - - 0.9284 0.9997 221125_WJC_METTL3_EV_vs_WT_F04.06146.06146.2 0.0105 14-Oct R.TQNVLGEK[136.11].G "sp|P23396|RS3_HUMAN,tr|E9PL09|E9PL09_HUMAN,tr|E9PK82|E9PK82_HUMAN,tr|F2Z2S8|F2Z2S8_HUMAN,tr|H0YCJ7|H0YCJ7_HUMAN,tr|E9PQ96|E9PQ96_HUMAN,tr|E9PJH4|E9PJH4_HUMAN,tr|E9PPU1|E9PPU1_HUMAN,tr|H0YF32|H0YF32_HUMAN" 9 895.4854 0.81 42093 6146 2 895.485033 448.75 40S ribosomal protein S3 OS=Homo sapiens OX=9606 GN=RPS3 PE=1 SV=2 5.66 1704.7 - 9.82E+06 - - - -0.4612 - 1.814 0.369 - 473 1 2 0 -0.0004 8 0 0 0 2.06E+09 2.54E+09 - - - 3.5624 0.9999 221125_WJC_METTL3_EV_vs_WT_F04.06152.06152.2 5.71E-06 14-Sep R.MGANNLER[166.11].M "sp|P52272|HNRPM_HUMAN,tr|M0R2I7|M0R2I7_HUMAN,tr|A0A087X0X3|A0A087X0X3_HUMAN,tr|M0QZM1|M0QZM1_HUMAN" 4 913.4315 1.68 42097 6152 2 913.430342 457.723 Heterogeneous nuclear ribonucleoprotein M OS=Homo sapiens OX=9606 GN=HNRNPM PE=1 SV=3 5.75 1705.4 - 3.82E+06 - - - -1.2896 - 1.983 0.55 - 329.6 1 2 0 -0.0012 8 0 0 0 6.93E+08 4.13E+08 - - - 5.1677 0.9975 221125_WJC_METTL3_EV_vs_WT_F04.06153.06153.2 0.155 12-May R.YSTSLEK.H "sp|Q15020|SART3_HUMAN,tr|H0YHU8|H0YHU8_HUMAN,tr|A0A499FI31|A0A499FI31_HUMAN" 3 826.4072 6.26 42098 6153 2 826.406535 414.2109 Squamous cell carcinoma antigen recognized by T-cells 3 OS=Homo sapiens OX=9606 GN=SART3 PE=1 SV=1 6 1705.4 - 4.50E+06 - - - -0.864 - 1.353 0.231 - 65.9 1 2 0 -0.0007 7 0 0 0 3.29E+08 5.25E+07 - - - 1.7049 0.9993 221125_WJC_METTL3_EV_vs_WT_F04.06154.06154.2 0.0983 14-Aug K.SAVLQEAR[166.11].V "sp|Q9Y678|COPG1_HUMAN,sp|Q9UBF2|COPG2_HUMAN" 2 882.4799 0.58 42099 6154 2 882.479339 442.2472 Coatomer subunit gamma-1 OS=Homo sapiens OX=9606 GN=COPG1 PE=1 SV=1 5.72 1705.5 - 1.80E+06 - - - -0.5791 - 1.791 0.264 - 325 1 2 0 -0.0005 8 0 0 0 4.16E+07 7.19E+07 - - - 2.7484 0.7846 221125_WJC_METTL3_EV_vs_WT_F04.06155.06155.2 1.88 14-Aug R.VR[166.11]EEILAK[136.11].G sp|Q9H0D6|XRN2_HUMAN 1 974.588 1 42100 6155 2 974.587416 488.3013 5'-3' exoribonuclease 2 OS=Homo sapiens OX=9606 GN=XRN2 PE=1 SV=1 6.11 1705.6 - 842896 - - - -0.5489 - 1.357 0.014 - 225.7 1 2 1 -0.0005 8 0 0 0 1.16E+08 1.16E+08 - - - 0.0649 0.9792 221125_WJC_METTL3_EV_vs_WT_F04.06159.06159.2 0.000277 12-Jun A.PGFGDNR.K "sp|P10809|CH60_HUMAN,tr|A0A7I2V2X6|A0A7I2V2X6_HUMAN,tr|A0A7I2YQK6|A0A7I2YQK6_HUMAN,tr|A0A7I2V599|A0A7I2V599_HUMAN,tr|A0A7I2V5M1|A0A7I2V5M1_HUMAN" 5 761.3457 1.39 42102 6159 2 761.345136 381.6801 "60 kDa heat shock protein, mitochondrial OS=Homo sapiens OX=9606 GN=HSPD1 PE=1 SV=2" 6.27 1706.1 - 1.88E+06 - - - -0.6777 - 1.332 0.476 - 94.6 1 1 0 -0.0005 7 0 0 0 3.94E+08 2.84E+08 - - - 3.4649 0.9161 221125_WJC_METTL3_EV_vs_WT_F04.06160.06160.2 0.0292 18-Jun K.IISNASC[160.03]TTN.C "sp|P04406|G3P_HUMAN,tr|E7EUT5|E7EUT5_HUMAN" 2 1079.4917 - 42103 6160 2 1079.491132 540.7531 Glyceraldehyde-3-phosphate dehydrogenase OS=Homo sapiens OX=9606 GN=GAPDH PE=1 SV=3 5.52 1706.2 - 627819 - - - -0.5484 - 1.17 0.347 - 99.2 1 1 0 -0.0006 10 0 0 0 - - - - - 2.042 0.9945 221125_WJC_METTL3_EV_vs_WT_F04.06168.06168.2 0.401 12-Aug K.QSVELC[160.03]K[136.11].K "sp|Q00610|CLH1_HUMAN,sp|P53675|CLH2_HUMAN,tr|K7EJJ5|K7EJJ5_HUMAN,tr|J3KS13|J3KS13_HUMAN,tr|H0YGJ9|H0YGJ9_HUMAN,tr|A0A087WXH4|A0A087WXH4_HUMAN,tr|A0A087WVQ6|A0A087WVQ6_HUMAN,tr|J3KRF5|J3KRF5_HUMAN" 8 870.4361 0.2 42108 6168 2 870.436198 436.2253 Clathrin heavy chain 1 OS=Homo sapiens OX=9606 GN=CLTC PE=1 SV=5 5.99 1707 - 2.09E+06 - - - 0.1666 - 1.583 0.075 - 261.5 1 2 0 0.0001 7 0 0 0 1.69E+07 8.53E+07 - - - 1.0503 0.9993 221125_WJC_METTL3_EV_vs_WT_F04.06177.06177.2 5.13E-05 16-Oct R.VADNSFDAK.R "sp|Q14978|NOLC1_HUMAN,tr|A0A0A0MRM9|A0A0A0MRM9_HUMAN" 2 965.4454 1.97 42111 6177 2 965.44215 483.73 Nucleolar and coiled-body phosphoprotein 1 OS=Homo sapiens OX=9606 GN=NOLC1 PE=1 SV=2 4.21 1708.2 - 2.59E+06 - - - -3.3922 - 1.987 0.529 - 283.3 1 2 0 -0.0033 9 0 0 0 6.44E+08 3.27E+08 - - - 4.9336 0.9971 221125_WJC_METTL3_EV_vs_WT_F04.06179.06179.2 0.000313 16-Sep R.FDSPESAEK[136.11].A "sp|Q9P2K5|MYEF2_HUMAN,tr|A0A0A0MR39|A0A0A0MR39_HUMAN,tr|A0A0C4DGV1|A0A0C4DGV1_HUMAN,tr|A0A087WUT0|A0A087WUT0_HUMAN,tr|H0YKS1|H0YKS1_HUMAN,tr|A0A0A0MQW0|A0A0A0MQW0_HUMAN" 6 1016.4542 1.39 42112 6179 2 1016.452313 509.2344 Myelin expression factor 2 OS=Homo sapiens OX=9606 GN=MYEF2 PE=1 SV=3 4.14 1708.4 - 444272 - - - -1.8624 - 1.681 0.203 - 216.8 1 2 0 -0.0019 9 0 0 0 1.68E+08 1.21E+08 - - - 2.0424 0.9991 221125_WJC_METTL3_EV_vs_WT_F04.06187.06187.2 0.0194 14-Jul R.TQNVLGEK.G "sp|P23396|RS3_HUMAN,tr|E9PL09|E9PL09_HUMAN,tr|E9PK82|E9PK82_HUMAN,tr|F2Z2S8|F2Z2S8_HUMAN,tr|H0YCJ7|H0YCJ7_HUMAN,tr|E9PQ96|E9PQ96_HUMAN,tr|E9PJH4|E9PJH4_HUMAN,tr|E9PPU1|E9PPU1_HUMAN,tr|H0YF32|H0YF32_HUMAN" 9 887.4712 0.81 42115 6187 2 887.469626 444.7429 40S ribosomal protein S3 OS=Homo sapiens OX=9606 GN=RPS3 PE=1 SV=2 5.66 1709.4 - 5.39E+07 - - - -1.8254 - 1.553 0.375 - 226.8 1 2 0 -0.0016 8 0 0 0 2.06E+09 2.55E+09 - - - 3.1378 0.999 221125_WJC_METTL3_EV_vs_WT_F04.06199.06199.2 0.165 18-Jul K.MEGGTENDLR.L sp|Q9BXP5|SRRT_HUMAN 1 1120.4819 1.01 42122 6199 2 1120.48048 561.2482 Serrate RNA effector molecule homolog OS=Homo sapiens OX=9606 GN=SRRT PE=1 SV=1 4.14 1710.8 - 264290 - - - -1.2557 - 1.434 0.353 - 205.6 1 2 0 -0.0014 10 0 0 0 3.12E+07 3.08E+07 - - - 2.654 0.895 221125_WJC_METTL3_EV_vs_WT_F04.06214.06214.2 0.0183 12-Jun K.QNKPTGF.A "sp|P78406|RAE1L_HUMAN,tr|E9PQ57|E9PQ57_HUMAN" 2 790.3974 0.61 42131 6214 2 790.39758 396.206 mRNA export factor OS=Homo sapiens OX=9606 GN=RAE1 PE=1 SV=1 8.75 1712.7 - 1.21E+06 - - - 0.2872 - 1.213 0.296 - 135.2 1 1 0 0.0002 7 0 0 0 6.60E+07 1.08E+08 - - - 1.839 0.9998 221125_WJC_METTL3_EV_vs_WT_F04.06218.06218.2 0.0197 18-Nov K.MEGGTENDLR[166.11].L sp|Q9BXP5|SRRT_HUMAN 1 1130.4902 1.01 42132 6218 2 1130.488693 566.2524 Serrate RNA effector molecule homolog OS=Homo sapiens OX=9606 GN=SRRT PE=1 SV=1 4.14 1713.3 - 1.44E+06 - - - -1.295 - 2.041 0.47 - 521.3 1 2 0 -0.0015 10 0 0 0 3.12E+07 3.08E+07 - - - 4.5034 0.9967 221125_WJC_METTL3_EV_vs_WT_F04.06228.06228.2 0.00268 20-Oct K.GIGSTVQPAAK[136.11].L "sp|Q7Z589|EMSY_HUMAN,tr|H0YCS3|H0YCS3_HUMAN,tr|E9PMC9|E9PMC9_HUMAN" 3 1035.5804 0.78 42138 6228 2 1035.57634 518.7975 BRCA2-interacting transcriptional repressor EMSY OS=Homo sapiens OX=9606 GN=EMSY PE=1 SV=2 8.75 1714.4 - 532192 - - - -3.9292 - 1.683 0.388 - 229.8 1 2 0 -0.0041 11 0 0 0 1.42E+07 1.81E+07 - - - 3.3138 0.9983 221125_WJC_METTL3_EV_vs_WT_F04.06232.06232.2 0.0154 14-Aug K.SLSDTVEK.L "sp|Q14203|DCTN1_HUMAN,tr|A0A804CDA6|A0A804CDA6_HUMAN,tr|E7EX90|E7EX90_HUMAN,tr|A0A7P0Z4C3|A0A7P0Z4C3_HUMAN,tr|E7EWF7|E7EWF7_HUMAN" 5 877.4393 0.51 42140 6232 2 877.437396 439.7269 Dynactin subunit 1 OS=Homo sapiens OX=9606 GN=DCTN1 PE=1 SV=3 4.37 1714.9 - 3.77E+06 - - - -2.1437 - 1.503 0.323 - 158.8 1 2 0 -0.0019 8 0 0 0 6.68E+08 1.30E+09 - - - 2.655 0.9595 221125_WJC_METTL3_EV_vs_WT_F04.06233.06233.2 0.000236 14-Aug Y.FENVDDAK.E "sp|P62995|TRA2B_HUMAN,tr|H7BXF3|H7BXF3_HUMAN" 2 936.4189 1.84 42141 6233 2 936.416469 469.2167 Transformer-2 protein homolog beta OS=Homo sapiens OX=9606 GN=TRA2B PE=1 SV=1 4.03 1715 - 2.49E+06 - - - -2.5704 - 1.69 0.455 - 179.3 1 1 0 -0.0024 8 0 0 0 1.10E+08 5.99E+07 - - - 3.9834 0.9967 221125_WJC_METTL3_EV_vs_WT_F04.06235.06235.2 0.00436 14-Aug R.C[160.03]LDGQPMK.C "sp|Q9BY77|PDIP3_HUMAN,tr|F6VRR5|F6VRR5_HUMAN" 2 947.4205 1.43 42143 6235 2 947.417113 474.7175 Polymerase delta-interacting protein 3 OS=Homo sapiens OX=9606 GN=POLDIP3 PE=1 SV=2 5.83 1715.1 - 1.58E+06 - - - -3.5465 - 1.645 0.337 - 257.5 1 2 0 -0.0034 8 0 0 0 1.79E+08 1.26E+08 - - - 3.0302 0.9974 221125_WJC_METTL3_EV_vs_WT_F04.06241.06241.2 0.0312 14-Jul R.EIEDPEDR[166.11].K "sp|P27824|CALX_HUMAN,tr|A0A7P0T937|A0A7P0T937_HUMAN,tr|A0A7P0T840|A0A7P0T840_HUMAN,tr|A0A7P0TB65|A0A7P0TB65_HUMAN,tr|A0A7P0TAE9|A0A7P0TAE9_HUMAN,tr|D6RGY2|D6RGY2_HUMAN,tr|A0A7P0T8G1|A0A7P0T8G1_HUMAN,tr|A0A7P0Z4D6|A0A7P0Z4D6_HUMAN,tr|A0A7P0Z484|A0A7P0Z484_HUMAN,tr|A0A7P0TAR9|A0A7P0TAR9_HUMAN,tr|A0A7P0T9L0|A0A7P0T9L0_HUMAN" 11 1011.4384 1.45 42146 6241 2 1011.435002 506.7265 Calnexin OS=Homo sapiens OX=9606 GN=CANX PE=1 SV=2 3.83 1715.9 - 745615 - - - -3.3981 - 1.406 0.42 - 215.8 1 2 0 -0.0034 8 0 0 0 2.69E+08 1.85E+08 - - - 3.1697 0.9986 221125_WJC_METTL3_EV_vs_WT_F04.06243.06243.2 0.101 14-Jul K.LLEGEESR.L "sp|P08670|VIME_HUMAN,sp|Q9NSB2|KRT84_HUMAN,sp|P17661|DESM_HUMAN,sp|P05787|K2C8_HUMAN,sp|P41219|PERI_HUMAN,sp|Q7Z794|K2C1B_HUMAN,sp|P04264|K2C1_HUMAN,sp|P08729|K2C7_HUMAN,tr|H7C5W5|H7C5W5_HUMAN,tr|B0YJC5|B0YJC5_HUMAN,tr|B0YJC4|B0YJC4_HUMAN" 11 931.4611 1.02 42148 6243 2 931.459535 466.7378 Vimentin OS=Homo sapiens OX=9606 GN=VIM PE=1 SV=4 4.25 1716.1 - 3.10E+06 - - - -1.6533 - 1.403 0.335 - 149.1 1 2 0 -0.0015 8 0 0 0 5.11E+08 5.03E+08 - - - 2.5361 0.9901 221125_WJC_METTL3_EV_vs_WT_F04.06244.06244.2 0.28 14-Jul K.FAQSTNLK.S "sp|P25490|TYY1_HUMAN,sp|O15391|TYY2_HUMAN,tr|H0YJV7|H0YJV7_HUMAN" 3 907.4763 1.13 42149 6244 2 907.474715 454.7454 Transcriptional repressor protein YY1 OS=Homo sapiens OX=9606 GN=YY1 PE=1 SV=2 8.75 1716.1 - 3.01E+06 - - - -1.7808 - 1.247 0.182 - 101.6 1 2 0 -0.0016 8 0 0 0 1.00E+08 8.91E+07 - - - 1.0505 0.9826 221125_WJC_METTL3_EV_vs_WT_F04.06245.06245.2 0.000364 14-Sep Y.FENVDDAK[136.11].E "sp|P62995|TRA2B_HUMAN,tr|H7BXF3|H7BXF3_HUMAN" 2 944.4331 1.83 42150 6245 2 944.431309 473.2238 Transformer-2 protein homolog beta OS=Homo sapiens OX=9606 GN=TRA2B PE=1 SV=1 4.03 1716.2 - 1.96E+06 - - - -1.871 - 1.724 0.517 - 221.7 1 1 0 -0.0018 8 0 0 0 1.10E+08 5.99E+07 - - - 4.5016 0.9975 221125_WJC_METTL3_EV_vs_WT_F04.06250.06250.2 0.00488 22-Nov R.LLQQGTAPAQAK[136.11].A sp|Q86YP4|P66A_HUMAN 1 1232.6968 1.55 42153 6250 2 1232.692966 617.3557 Transcriptional repressor p66-alpha OS=Homo sapiens OX=9606 GN=GATAD2A PE=1 SV=1 8.75 1716.8 - 633489 - - - -3.1395 - 1.589 0.375 - 227.6 1 2 0 -0.0039 12 0 0 0 4.51E+07 2.90E+07 - - - 3.028 0.9927 221125_WJC_METTL3_EV_vs_WT_F04.06254.06254.2 0.658 14-Aug K.LAQVQVQK[136.11].D sp|Q01780|EXOSX_HUMAN 1 920.5535 1.26 42155 6254 2 920.555708 461.284 Exosome component 10 OS=Homo sapiens OX=9606 GN=EXOSC10 PE=1 SV=2 8.75 1717.2 - 1.69E+06 - - - 2.4355 - 1.515 0.184 - 195.3 1 2 0 0.0022 8 0 0 0 8.07E+07 6.42E+07 - - - 1.6522 0.9425 221125_WJC_METTL3_EV_vs_WT_F04.06255.06255.2 1.42 16-Mar R.IMNEEDPEK[136.11].Q "sp|Q96A33|CCD47_HUMAN,tr|J3QR89|J3QR89_HUMAN,tr|A0A087WYW6|A0A087WYW6_HUMAN" 3 1111.4947 1.93 42156 6255 2 1111.494115 556.7546 PAT complex subunit CCDC47 OS=Homo sapiens OX=9606 GN=CCDC47 PE=1 SV=1 4 1717.4 - 0 - - - -0.5173 - 0.641 0.235 - 30 1 2 0 -0.0006 9 0 0 0 1.56E+07 8.11E+06 - - - -0.5101 0.9778 221125_WJC_METTL3_EV_vs_WT_F04.06258.06258.2 0.523 14-May K.STEEPIVK.V sp|Q13618|CUL3_HUMAN 1 901.4757 1.5 42157 6258 2 901.473421 451.7451 Cullin-3 OS=Homo sapiens OX=9606 GN=CUL3 PE=1 SV=2 4.53 1717.8 - 2.06E+06 - - - -2.487 - 1.195 0.188 - 94.5 2 2 0 -0.0022 8 0 0 0 4.91E+07 3.26E+07 - - - 0.8317 0.9973 221125_WJC_METTL3_EV_vs_WT_F04.06262.06262.2 0.168 14-Aug K.LAQVQVQK.D sp|Q01780|EXOSX_HUMAN 1 912.5393 1.26 42159 6262 2 912.537418 457.2769 Exosome component 10 OS=Homo sapiens OX=9606 GN=EXOSC10 PE=1 SV=2 8.75 1718.2 - 2.97E+06 - - - -2.0251 - 1.851 0.173 - 147.1 1 2 0 -0.0018 8 0 0 0 8.08E+07 6.42E+07 - - - 2.1752 0.9973 221125_WJC_METTL3_EV_vs_WT_F04.06265.06265.2 0.000323 16-Oct R.FDSPESAEK.A "sp|Q9P2K5|MYEF2_HUMAN,tr|A0A0A0MR39|A0A0A0MR39_HUMAN,tr|A0A0C4DGV1|A0A0C4DGV1_HUMAN,tr|A0A087WUT0|A0A087WUT0_HUMAN,tr|H0YKS1|H0YKS1_HUMAN,tr|A0A0A0MQW0|A0A0A0MQW0_HUMAN" 6 1008.44 1.39 42161 6265 2 1008.437666 505.2273 Myelin expression factor 2 OS=Homo sapiens OX=9606 GN=MYEF2 PE=1 SV=3 4.14 1718.5 - 2.40E+06 - - - -2.3204 - 1.868 0.208 - 286.6 1 2 0 -0.0023 9 0 0 0 1.69E+08 1.21E+08 - - - 2.3843 0.9997 221125_WJC_METTL3_EV_vs_WT_F04.06270.06270.2 0.000953 14-Aug R.EIEDPEDR.K "sp|P27824|CALX_HUMAN,tr|A0A7P0T937|A0A7P0T937_HUMAN,tr|A0A7P0T840|A0A7P0T840_HUMAN,tr|A0A7P0TB65|A0A7P0TB65_HUMAN,tr|A0A7P0TAE9|A0A7P0TAE9_HUMAN,tr|D6RGY2|D6RGY2_HUMAN,tr|A0A7P0T8G1|A0A7P0T8G1_HUMAN,tr|A0A7P0Z4D6|A0A7P0Z4D6_HUMAN,tr|A0A7P0Z484|A0A7P0Z484_HUMAN,tr|A0A7P0TAR9|A0A7P0TAR9_HUMAN,tr|A0A7P0T9L0|A0A7P0T9L0_HUMAN" 11 1001.4302 1.45 42164 6270 2 1001.43037 501.7224 Calnexin OS=Homo sapiens OX=9606 GN=CANX PE=1 SV=2 3.83 1719.1 - 2.47E+06 - - - 0.2007 - 1.451 0.443 - 273.1 1 2 0 0.0002 8 0 0 0 2.69E+08 1.86E+08 - - - 3.4356 0.979 221125_WJC_METTL3_EV_vs_WT_F04.06273.06273.2 1.26 16-May R.HQC[160.03]FHIGEK[136.11].C sp|A6NK53|ZN233_HUMAN 1 1162.5433 0.01 42167 6273 2 1162.542018 582.2789 Zinc finger protein 233 OS=Homo sapiens OX=9606 GN=ZNF233 PE=2 SV=3 6.91 1719.3 - 1.06E+06 - - - -1.1131 - 1.193 0.098 - 61.8 1 2 0 -0.0013 9 0 0 0 1.06E+06 7.65E+07 - - - 0.275 0.9998 221125_WJC_METTL3_EV_vs_WT_F04.06284.06284.2 2.70E-05 20-Oct K.VAAGTLDASTK[136.11].L "sp|Q15003|CND2_HUMAN,tr|C9J470|C9J470_HUMAN,tr|E9PHA2|E9PHA2_HUMAN" 3 1040.5593 0.89 42173 6284 2 1040.558339 521.2869 Condensin complex subunit 2 OS=Homo sapiens OX=9606 GN=NCAPH PE=1 SV=3 5.81 1720.9 - 453636 - - - -0.961 - 2.107 0.442 - 306.9 1 2 0 -0.001 11 0 0 0 6.23E+07 7.02E+07 - - - 4.3214 0.9079 221125_WJC_METTL3_EV_vs_WT_F04.06287.06287.2 0.159 12-Jun A.PGFGDNR[166.11].K "sp|P10809|CH60_HUMAN,tr|A0A7I2V2X6|A0A7I2V2X6_HUMAN,tr|A0A7I2YQK6|A0A7I2YQK6_HUMAN,tr|A0A7I2V599|A0A7I2V599_HUMAN,tr|A0A7I2V5M1|A0A7I2V5M1_HUMAN" 5 771.3539 1.39 42174 6287 2 771.354169 386.6842 "60 kDa heat shock protein, mitochondrial OS=Homo sapiens OX=9606 GN=HSPD1 PE=1 SV=2" 6.27 1721.3 - 1.53E+06 - - - 0.3202 - 1.315 0.278 - 114.4 1 1 0 0.0002 7 0 0 0 3.94E+08 2.84E+08 - - - 1.9619 0.9989 221125_WJC_METTL3_EV_vs_WT_F04.06288.06288.2 0.0269 14-Jul K.DVPNNQLR[166.11].H "sp|Q9BYJ9|YTHD1_HUMAN,sp|Q7Z739|YTHD3_HUMAN,tr|A0A087X0Q1|A0A087X0Q1_HUMAN,tr|A0A024R7W5|A0A024R7W5_HUMAN,tr|A0A087WY31|A0A087WY31_HUMAN" 5 964.4966 1.86 42175 6288 2 964.496116 483.2556 YTH domain-containing family protein 1 OS=Homo sapiens OX=9606 GN=YTHDF1 PE=1 SV=1 5.84 1721.4 - 1.42E+06 - - - -0.4635 - 1.331 0.33 - 201.2 1 2 0 -0.0004 8 0 0 0 2.22E+08 1.19E+08 - - - 2.3406 0.9955 221125_WJC_METTL3_EV_vs_WT_F04.06290.06290.2 0.753 14-Sep K.LSPEEVQK[136.11].N "sp|Q9Y3D7|TIM16_HUMAN,tr|I3L3T0|I3L3T0_HUMAN,tr|A0A0A6YYL4|A0A0A6YYL4_HUMAN,tr|I3L1U7|I3L1U7_HUMAN,tr|I3L0X9|I3L0X9_HUMAN" 5 936.5008 1.43 42177 6290 2 936.500487 469.2577 Mitochondrial import inner membrane translocase subunit TIM16 OS=Homo sapiens OX=9606 GN=PAM16 PE=1 SV=2 4.53 1721.5 - 2.26E+06 - - - -0.2936 - 1.453 0.137 - 229.3 1 2 0 -0.0003 8 0 0 0 2.51E+08 1.75E+08 - - - 1.1796 0.9968 221125_WJC_METTL3_EV_vs_WT_F04.06294.06294.2 2.65E-05 20-Nov K.VAAGTLDASTK.L "sp|Q15003|CND2_HUMAN,tr|C9J470|C9J470_HUMAN,tr|E9PHA2|E9PHA2_HUMAN" 3 1032.5451 0.89 42179 6294 2 1032.551083 517.2798 Condensin complex subunit 2 OS=Homo sapiens OX=9606 GN=NCAPH PE=1 SV=3 5.81 1722 - 991865 - - - 5.7566 - 2.383 0.534 - 315 1 2 0 0.0059 11 0 0 0 6.23E+07 7.00E+07 - - - 5.3324 0.9948 221125_WJC_METTL3_EV_vs_WT_F04.06296.06296.2 0.463 14-Aug K.LQQVMQAK.K "sp|Q86U86|PB1_HUMAN,tr|H0Y5B5|H0Y5B5_HUMAN,tr|E7EVG2|E7EVG2_HUMAN" 3 944.5113 2.86 42181 6296 2 944.51192 473.2629 Protein polybromo-1 OS=Homo sapiens OX=9606 GN=PBRM1 PE=1 SV=1 8.75 1722.2 - 2.61E+06 - - - 0.6173 - 1.416 0.145 - 179.2 1 2 0 0.0006 8 0 0 0 9.98E+07 3.49E+07 - - - 1.1608 0.9976 221125_WJC_METTL3_EV_vs_WT_F04.06297.06297.2 0.0381 16-Jun R.AAASTDYYK.R sp|P08559|ODPA_HUMAN 1 988.4502 1.19 42182 6297 2 988.451436 495.2324 "Pyruvate dehydrogenase E1 component subunit alpha, somatic form, mitochondrial OS=Homo sapiens OX=9606 GN=PDHA1 PE=1 SV=3" 5.88 1722.3 - 677130 - - - 1.2747 - 1.282 0.302 - 108.7 1 2 0 0.0013 9 0 0 0 2.91E+07 2.45E+07 - - - 1.9899 0.9996 221125_WJC_METTL3_EV_vs_WT_F04.06303.06303.2 0.00131 14-Jul R.DVTYEEAK[136.11].Q "sp|P61106|RAB14_HUMAN,tr|X6RFL8|X6RFL8_HUMAN" 2 961.4484 2.05 42186 6303 2 961.448393 481.7315 Ras-related protein Rab-14 OS=Homo sapiens OX=9606 GN=RAB14 PE=1 SV=4 4.14 1723 - 1.92E+06 - - - 0.001 - 1.392 0.445 - 130 1 2 0 0 8 0 0 0 1.75E+08 8.52E+07 - - - 3.3253 0.9925 221125_WJC_METTL3_EV_vs_WT_F04.06304.06304.2 0.0567 14-Aug K.LSPEEVQK.N "sp|Q9Y3D7|TIM16_HUMAN,tr|I3L3T0|I3L3T0_HUMAN,tr|A0A0A6YYL4|A0A0A6YYL4_HUMAN,tr|I3L1U7|I3L1U7_HUMAN,tr|I3L0X9|I3L0X9_HUMAN" 5 928.4866 1.43 42187 6304 2 928.486158 465.2506 Mitochondrial import inner membrane translocase subunit TIM16 OS=Homo sapiens OX=9606 GN=PAM16 PE=1 SV=2 4.53 1723.1 - 4.40E+06 - - - -0.4351 - 1.482 0.081 - 233.2 1 2 0 -0.0004 8 0 0 0 2.49E+08 1.74E+08 - - - 0.8256 0.9979 221125_WJC_METTL3_EV_vs_WT_F04.06308.06308.2 0.504 12-Jul K.ITITNDK[136.11].G "sp|P54652|HSP72_HUMAN,sp|P0DMV8|HS71A_HUMAN,sp|P34931|HS71L_HUMAN,sp|P11142|HSP7C_HUMAN,sp|P0DMV9|HS71B_HUMAN,sp|P17066|HSP76_HUMAN,tr|E9PNE6|E9PNE6_HUMAN,tr|A8K7Q2|A8K7Q2_HUMAN,tr|E9PKE3|E9PKE3_HUMAN,tr|E9PM13|E9PM13_HUMAN,tr|E9PS65|E9PS65_HUMAN,tr|Q53FA3|Q53FA3_HUMAN,tr|V9GZ37|V9GZ37_HUMAN,tr|A0A0G2JIW1|A0A0G2JIW1_HUMAN" 14 811.4531 0.34 42189 6308 2 811.453153 406.7338 Heat shock-related 70 kDa protein 2 OS=Homo sapiens OX=9606 GN=HSPA2 PE=1 SV=1 5.84 1723.6 - 643874 - - - 0.0863 - 1.551 0.178 - 131.7 1 2 0 0.0001 7 0 0 0 1.70E+07 5.03E+07 - - - 1.7464 0.9997 221125_WJC_METTL3_EV_vs_WT_F04.06318.06318.2 0.0599 14-Nov R.R[166.11]LEEAALR[166.11].R "sp|Q96A33|CCD47_HUMAN,tr|A0A087WYW6|A0A087WYW6_HUMAN" 2 976.5569 1.19 42193 6318 2 976.556871 489.2857 PAT complex subunit CCDC47 OS=Homo sapiens OX=9606 GN=CCDC47 PE=1 SV=1 6.14 1724.8 - 1.23E+06 - - - 0.002 - 2.108 0.315 - 287 1 2 0 0 8 0 0 0 6.64E+07 5.58E+07 - - - 3.6167 0.9986 221125_WJC_METTL3_EV_vs_WT_F04.06321.06321.2 0.267 18-Oct M.GPAPAGEQLR.G "sp|Q9H6R4|NOL6_HUMAN,tr|A0A0A0MRW6|A0A0A0MRW6_HUMAN" 2 994.5196 0.64 42195 6321 2 994.518182 498.2671 Nucleolar protein 6 OS=Homo sapiens OX=9606 GN=NOL6 PE=1 SV=2 6 1725.2 - 577519 - - - -1.4188 - 2.031 0.186 - 415.2 1 2 0 -0.0014 10 0 0 0 3.34E+07 5.22E+07 - - - 2.3921 0.9996 221125_WJC_METTL3_EV_vs_WT_F04.06323.06323.2 0.000824 14-Jul R.FGGSYGGR.F sp|Q5BKZ1|ZN326_HUMAN 1 799.3613 1.09 42197 6323 2 799.360172 400.6879 DBIRD complex subunit ZNF326 OS=Homo sapiens OX=9606 GN=ZNF326 PE=1 SV=2 8.75 1725.3 - 1.25E+06 - - - -1.4136 - 1.67 0.431 - 102.9 1 2 0 -0.0011 8 0 0 0 4.36E+07 4.02E+07 - - - 3.7707 0.9999 221125_WJC_METTL3_EV_vs_WT_F04.06329.06329.2 9.65E-05 14-Sep K.C[160.03]EAAFATK.D "sp|P56270|MAZ_HUMAN,tr|H3BQI4|H3BQI4_HUMAN,tr|H3BQS2|H3BQS2_HUMAN,tr|I3L2Z5|I3L2Z5_HUMAN,tr|A0A087WWR2|A0A087WWR2_HUMAN" 5 896.4062 1.02 42200 6329 2 896.406077 449.2104 Myc-associated zinc finger protein OS=Homo sapiens OX=9606 GN=MAZ PE=1 SV=1 5.99 1726 - 837599 - - - -0.1406 - 2.016 0.573 - 410.7 1 2 0 -0.0001 8 0 0 0 1.90E+08 1.86E+08 - - - 5.3877 0.7736 221125_WJC_METTL3_EV_vs_WT_F04.06332.06332.2 6.23 14-Aug R.QIDGSLNR[166.11].T sp|Q93100|KPBB_HUMAN 1 911.47 1.55 42201 6332 2 911.47675 456.7423 Phosphorylase b kinase regulatory subunit beta OS=Homo sapiens OX=9606 GN=PHKB PE=1 SV=3 5.84 1726.5 - 1.13E+06 - - - 7.3903 - 1.535 0.141 - 260.5 1 2 0 0.0067 8 0 0 0 7.29E+07 4.70E+07 - - - 1.3727 0.9995 221125_WJC_METTL3_EV_vs_WT_F04.06343.06343.2 0.0333 16-Aug K.VQAELDETK.L "sp|O15498|YKT6_HUMAN,tr|A0A7I2V4L6|A0A7I2V4L6_HUMAN,tr|A0A7I2V3V7|A0A7I2V3V7_HUMAN,tr|H7C3K7|H7C3K7_HUMAN,tr|A0A7I2V3A1|A0A7I2V3A1_HUMAN" 5 1031.5135 3.82 42208 6343 2 1031.514739 516.764 Synaptobrevin homolog YKT6 OS=Homo sapiens OX=9606 GN=YKT6 PE=1 SV=1 4.14 1727.6 - 4.43E+06 - - - 1.1963 - 1.831 0.348 - 185.3 1 2 0 0.0012 9 0 0 0 1.11E+08 2.90E+07 - - - 3.3608 0.999 221125_WJC_METTL3_EV_vs_WT_F04.06345.06345.2 0.0123 14-Aug R.GVTQFGNK[136.11].Y sp|O43809|CPSF5_HUMAN 1 857.4487 0.7 42210 6345 2 857.44889 429.7316 Cleavage and polyadenylation specificity factor subunit 5 OS=Homo sapiens OX=9606 GN=NUDT21 PE=1 SV=1 8.75 1727.7 - 2.27E+06 - - - 0.2601 - 1.583 0.271 - 191.9 1 2 0 0.0002 8 0 0 0 5.26E+07 7.54E+07 - - - 2.4278 0.9997 221125_WJC_METTL3_EV_vs_WT_F04.06348.06348.2 0.0338 14-Dec R.RLEEAALR.R "sp|Q96A33|CCD47_HUMAN,tr|A0A087WYW6|A0A087WYW6_HUMAN" 2 956.5403 1.19 42211 6348 2 956.540013 479.2774 PAT complex subunit CCDC47 OS=Homo sapiens OX=9606 GN=CCDC47 PE=1 SV=1 6.14 1728.1 - 2.59E+06 - - - -0.3304 - 1.835 0.353 - 338.5 1 2 0 -0.0003 8 0 0 0 6.64E+07 5.57E+07 - - - 3.479 0.954 221125_WJC_METTL3_EV_vs_WT_F04.06349.06349.2 7.93 14-Jun K.QLSQLGQK[136.11].- "sp|Q8WVM8|SCFD1_HUMAN,tr|A0A7I2V4U2|A0A7I2V4U2_HUMAN,tr|A0A7I2V4B8|A0A7I2V4B8_HUMAN,tr|A0A7I2V5Z4|A0A7I2V5Z4_HUMAN,tr|B7Z5N7|B7Z5N7_HUMAN,tr|A0A7I2V5I2|A0A7I2V5I2_HUMAN,tr|A0A7I2V2U5|A0A7I2V2U5_HUMAN,tr|A0A7I2V448|A0A7I2V448_HUMAN,tr|A0A7I2V320|A0A7I2V320_HUMAN,tr|A0A7I2V3G4|A0A7I2V3G4_HUMAN,tr|A0A7I2V3B4|A0A7I2V3B4_HUMAN,tr|G3V2M8|G3V2M8_HUMAN,tr|A0A7I2V4R0|A0A7I2V4R0_HUMAN" 13 908.5171 0.94 42212 6349 2 908.515521 455.2658 Sec1 family domain-containing protein 1 OS=Homo sapiens OX=9606 GN=SCFD1 PE=1 SV=4 8.75 1728.2 - 872070 - - - -1.7171 - 1.139 0.092 - 138.1 2 2 0 -0.0016 8 0 0 0 2.88E+07 3.05E+07 - - - -0.0219 0.9996 221125_WJC_METTL3_EV_vs_WT_F04.06350.06350.2 0.00222 16-Sep R.LQDDNQELR[166.11].E sp|A6NKD9|CC85C_HUMAN 1 1139.5446 2.24 42213 6350 2 1139.545685 570.7796 Coiled-coil domain-containing protein 85C OS=Homo sapiens OX=9606 GN=CCDC85C PE=1 SV=1 4.03 1728.3 - 305683 - - - 0.9205 - 1.69 0.419 - 355.1 1 2 0 0.001 9 0 0 0 2.80E+07 1.25E+07 - - - 3.6535 0.9984 221125_WJC_METTL3_EV_vs_WT_F04.06351.06351.2 0.0233 16-Jul K.EQAELEAAR[166.11].Q sp|Q15149|PLEC_HUMAN 1 1025.5017 1.22 42214 6351 2 1025.501678 513.7581 Plectin OS=Homo sapiens OX=9606 GN=PLEC PE=1 SV=3 4.25 1728.4 - 225444 - - - -0.0293 - 1.425 0.257 - 144.9 1 2 0 0 9 0 0 0 9.50E+06 7.81E+06 - - - 1.9638 0.9978 221125_WJC_METTL3_EV_vs_WT_F04.06355.06355.2 0.0151 16-Sep K.VQAELDETK[136.11].L "sp|O15498|YKT6_HUMAN,tr|A0A7I2V4L6|A0A7I2V4L6_HUMAN,tr|A0A7I2V3V7|A0A7I2V3V7_HUMAN,tr|H7C3K7|H7C3K7_HUMAN,tr|A0A7I2V3A1|A0A7I2V3A1_HUMAN" 5 1039.5277 3.85 42216 6355 2 1039.527364 520.7711 Synaptobrevin homolog YKT6 OS=Homo sapiens OX=9606 GN=YKT6 PE=1 SV=1 4.14 1729 - 1.20E+06 - - - -0.328 - 1.724 0.147 - 253.2 1 2 0 -0.0003 9 0 0 0 1.12E+08 2.90E+07 - - - 1.7023 0.9896 221125_WJC_METTL3_EV_vs_WT_F04.06356.06356.2 0.292 12-Jul K.ITVVSEK.Q "sp|Q6P5R6|RL22L_HUMAN,tr|H0Y8C2|H0Y8C2_HUMAN,tr|C9JYQ9|C9JYQ9_HUMAN" 3 774.4487 2.24 42217 6356 2 774.447537 388.2316 60S ribosomal protein L22-like 1 OS=Homo sapiens OX=9606 GN=RPL22L1 PE=1 SV=2 6 1729.1 - 532705 - - - -1.5275 - 1.405 0.125 - 151.1 2 2 0 -0.0012 7 0 0 0 2.91E+07 1.30E+07 - - - 0.9068 0.9985 221125_WJC_METTL3_EV_vs_WT_F04.06357.06357.2 0.00222 14-Oct R.QVQNLVNK.S sp|P15924|DESP_HUMAN 1 941.5294 25.15 42218 6357 2 941.529995 471.772 Desmoplakin OS=Homo sapiens OX=9606 GN=DSP PE=1 SV=3 8.75 1729.1 - 1.12E+06 - - - 0.6001 - 1.587 0.227 - 337.7 1 2 0 0.0006 8 0 0 0 5.52E+07 2.19E+06 - - - 2.1103 0.9914 221125_WJC_METTL3_EV_vs_WT_F04.06358.06358.2 0.57 16-Jul K.R[166.11]VLLGETGK[136.11].E "sp|P62280|RS11_HUMAN,tr|M0QZC5|M0QZC5_HUMAN,tr|M0R1H6|M0R1H6_HUMAN" 3 989.5988 0.85 42219 6358 2 989.599694 495.8067 40S ribosomal protein S11 OS=Homo sapiens OX=9606 GN=RPS11 PE=1 SV=3 8.75 1729.2 - 393056 - - - 0.8529 - 1.295 0.146 - 176.5 1 2 0 0.0008 9 0 0 0 6.90E+06 8.11E+06 - - - 0.867 0.9958 221125_WJC_METTL3_EV_vs_WT_F04.06361.06361.2 0.141 14-Aug R.GELANEVK[136.11].V sp|P35579|MYH9_HUMAN 1 866.4589 1.63 42220 6361 2 866.46013 434.2367 Myosin-9 OS=Homo sapiens OX=9606 GN=MYH9 PE=1 SV=4 4.53 1729.7 - 1.50E+06 - - - 1.423 - 1.547 0.169 - 212.6 1 2 0 0.0012 8 0 0 0 7.47E+07 4.59E+07 - - - 1.6048 0.9999 221125_WJC_METTL3_EV_vs_WT_F04.06365.06365.2 9.23E-05 14-Sep K.C[160.03]EAAFATK[136.11].D "sp|P56270|MAZ_HUMAN,tr|H3BQI4|H3BQI4_HUMAN,tr|H3BQS2|H3BQS2_HUMAN,tr|I3L2Z5|I3L2Z5_HUMAN,tr|A0A087WWR2|A0A087WWR2_HUMAN" 5 904.4204 1.55 42223 6365 2 904.420891 453.2175 Myc-associated zinc finger protein OS=Homo sapiens OX=9606 GN=MAZ PE=1 SV=1 5.99 1730.1 - 6.93E+06 - - - 0.5396 - 2.043 0.513 - 508.8 1 2 0 0.0005 8 0 0 0 3.02E+08 1.95E+08 - - - 4.9845 0.9982 221125_WJC_METTL3_EV_vs_WT_F04.06367.06367.2 7.39E-05 18-Sep K.VSGTLDTPEK[136.11].T "sp|Q9BYG3|MK67I_HUMAN,tr|C9J808|C9J808_HUMAN,tr|H7BZL0|H7BZL0_HUMAN" 3 1053.5434 1.22 42224 6367 2 1053.545404 527.779 MKI67 FHA domain-interacting nucleolar phosphoprotein OS=Homo sapiens OX=9606 GN=NIFK PE=1 SV=1 4.37 1730.5 - 392473 - - - 1.9449 - 2.037 0.207 - 346.1 1 2 0 0.002 10 0 0 0 6.85E+07 5.61E+07 - - - 2.5552 0.9992 221125_WJC_METTL3_EV_vs_WT_F04.06373.06373.2 0.167 16-Aug K.AVELAANTK[136.11].G "sp|P29401|TKT_HUMAN,tr|A0A0B4J1R6|A0A0B4J1R6_HUMAN" 2 923.5167 1.82 42228 6373 2 923.516821 462.7656 Transketolase OS=Homo sapiens OX=9606 GN=TKT PE=1 SV=3 6.05 1731.2 - 1.19E+06 - - - 0.0812 - 1.826 0.244 - 207 1 2 0 0.0001 9 0 0 0 5.50E+07 3.03E+07 - - - 2.5851 0.9998 221125_WJC_METTL3_EV_vs_WT_F04.06374.06374.2 2.18E-05 18-Nov K.VSGTLDTPEK.T "sp|Q9BYG3|MK67I_HUMAN,tr|C9J808|C9J808_HUMAN,tr|H7BZL0|H7BZL0_HUMAN" 3 1045.5292 1.23 42229 6374 2 1045.530565 523.7719 MKI67 FHA domain-interacting nucleolar phosphoprotein OS=Homo sapiens OX=9606 GN=NIFK PE=1 SV=1 4.37 1731.4 - 634471 - - - 1.3486 - 2.004 0.496 - 604.3 1 2 0 0.0014 10 0 0 0 6.93E+07 5.61E+07 - - - 4.6444 0.9961 221125_WJC_METTL3_EV_vs_WT_F04.06380.06380.2 0.497 12-Jul K.RVTIMPK.D "sp|Q5TEC6|H3PS2_HUMAN,sp|Q16695|H31T_HUMAN,sp|P84243|H33_HUMAN,sp|Q6NXT2|H3C_HUMAN,sp|Q71DI3|H32_HUMAN,sp|P68431|H31_HUMAN,tr|K7EK07|K7EK07_HUMAN,tr|A0A590UJL8|A0A590UJL8_HUMAN" 8 843.5 0.85 42233 6380 2 843.500341 422.7573 Histone HIST2H3PS2 OS=Homo sapiens OX=9606 GN=H3-2 PE=1 SV=1 11 1732.2 - 9.69E+06 - - - 0.3521 - 1.385 0.168 - 268.9 1 2 0 0.0003 7 0 0 0 8.41E+08 9.93E+08 - - - 1.3138 0.9959 221125_WJC_METTL3_EV_vs_WT_F04.06381.06381.2 0.206 16-Jun K.LTETQGELK.D "sp|Q9Y448|SKAP_HUMAN,tr|H0YM11|H0YM11_HUMAN,tr|V9GY01|V9GY01_HUMAN" 3 1017.5342 3.05 42234 6381 2 1017.535104 509.7744 Small kinetochore-associated protein OS=Homo sapiens OX=9606 GN=KNSTRN PE=1 SV=2 4.53 1732.2 - 737958 - - - 0.8491 - 1.464 0.171 - 108.3 1 2 0 0.0009 9 0 0 0 1.44E+07 4.73E+06 - - - 1.4065 0.98 221125_WJC_METTL3_EV_vs_WT_F04.06389.06389.2 2.97 12-Aug R.IDKPILK.A "sp|P62917|RL8_HUMAN,sp|P01909|DQA1_HUMAN,tr|E9PKZ0|E9PKZ0_HUMAN,tr|E9PP36|E9PP36_HUMAN,tr|E9PKU4|E9PKU4_HUMAN,tr|Q5Y7D2|Q5Y7D2_HUMAN" 6 825.5324 0.83 42240 6389 2 825.535599 413.7735 60S ribosomal protein L8 OS=Homo sapiens OX=9606 GN=RPL8 PE=1 SV=2 8.59 1733.2 - 2.01E+06 - - - 3.8872 - 1.604 0.154 - 160.9 1 2 0 0.0032 7 0 0 0 4.30E+07 5.19E+07 - - - 1.6746 0.9989 221125_WJC_METTL3_EV_vs_WT_F04.06390.06390.2 0.0658 14-Aug K.YC[160.03]VEEEEK.A "sp|P78347|GTF2I_HUMAN,tr|C9J6M0|C9J6M0_HUMAN,tr|A0A494C1K3|A0A494C1K3_HUMAN" 3 1084.4383 1.45 42241 6390 2 1084.439109 543.2264 General transcription factor II-I OS=Homo sapiens OX=9606 GN=GTF2I PE=1 SV=2 4.09 1733.4 - 348725 - - - 0.7543 - 1.463 0.306 - 182.2 1 2 0 0.0008 8 0 0 0 6.91E+07 4.75E+07 - - - 2.4484 0.9366 221125_WJC_METTL3_EV_vs_WT_F04.06391.06391.2 0.227 16-Jun K.LTETQGELK[136.11].D "sp|Q9Y448|SKAP_HUMAN,tr|H0YM11|H0YM11_HUMAN,tr|V9GY01|V9GY01_HUMAN" 3 1025.5484 3.2 42242 6391 2 1025.551769 513.7815 Small kinetochore-associated protein OS=Homo sapiens OX=9606 GN=KNSTRN PE=1 SV=2 4.53 1733.5 - 320194 - - - 3.2461 - 1.485 0.059 - 82.1 2 2 0 0.0033 9 0 0 0 1.43E+07 4.48E+06 - - - 0.4852 0.9953 221125_WJC_METTL3_EV_vs_WT_F04.06393.06393.2 0.361 16-Jun R.AELSEGQVR.Q "tr|F5H7S3|F5H7S3_HUMAN,tr|H0YKX5|H0YKX5_HUMAN,tr|H0YL42|H0YL42_HUMAN,tr|B7Z596|B7Z596_HUMAN,tr|H7BYY1|H7BYY1_HUMAN" 5 987.4985 13.22 42243 6393 2 987.498811 494.7565 Tropomyosin alpha-1 chain OS=Homo sapiens OX=9606 GN=TPM1 PE=1 SV=2 4.53 1733.7 - 3.24E+06 - - - 0.2916 - 1.354 0.17 - 176.5 1 2 0 0.0003 9 0 0 0 6.28E+08 4.75E+07 - - - 1.1733 0.9996 221125_WJC_METTL3_EV_vs_WT_F04.06395.06395.2 0.0194 12-Jul R.MSSSFDR[166.11].M "sp|Q9P2K5|MYEF2_HUMAN,tr|A0A0A0MR39|A0A0A0MR39_HUMAN,tr|A0A0C4DGV1|A0A0C4DGV1_HUMAN,tr|A0A087WUT0|A0A087WUT0_HUMAN,tr|H0YKS1|H0YKS1_HUMAN,tr|H0YN19|H0YN19_HUMAN,tr|A0A0A0MQW0|A0A0A0MQW0_HUMAN" 7 838.3519 1.1 42244 6395 2 838.35256 420.1832 Myelin expression factor 2 OS=Homo sapiens OX=9606 GN=MYEF2 PE=1 SV=3 5.59 1733.9 - 2.37E+06 - - - 0.8195 - 1.657 0.379 - 186.6 1 2 0 0.0007 7 0 0 0 1.34E+08 1.21E+08 - - - 3.4402 0.9989 221125_WJC_METTL3_EV_vs_WT_F04.06396.06396.2 0.0553 14-Aug R.AELDEVNK.S sp|Q03252|LMNB2_HUMAN 1 916.4502 0.9 42245 6396 2 916.450707 459.2324 Lamin-B2 OS=Homo sapiens OX=9606 GN=LMNB2 PE=1 SV=4 4.14 1734 - 2.19E+06 - - - 0.5794 - 1.5 0.291 - 282.5 1 2 0 0.0005 8 0 0 0 6.09E+07 6.75E+07 - - - 2.413 0.9764 221125_WJC_METTL3_EV_vs_WT_F04.06397.06397.2 1.3 12-Jun R.QAVELQR[166.11].D "sp|Q9H7D7|WDR26_HUMAN,tr|A0A7P0SXD0|A0A7P0SXD0_HUMAN,tr|A0A7I2YQL3|A0A7I2YQL3_HUMAN,tr|A0A7I2YQQ9|A0A7I2YQQ9_HUMAN,tr|A0A499FIZ0|A0A499FIZ0_HUMAN" 5 852.4693 2.22 42246 6397 2 852.469745 427.2419 WD repeat-containing protein 26 OS=Homo sapiens OX=9606 GN=WDR26 PE=1 SV=3 6 1734 - 880576 - - - 0.5384 - 1.321 0.062 - 191.4 4 2 0 0.0005 7 0 0 0 5.72E+07 2.58E+07 - - - 0.1119 0.9928 221125_WJC_METTL3_EV_vs_WT_F04.06403.06403.2 0.0436 20-Jul R.YLAAGSSNAVK.L sp|Q5HYI8|RABL3_HUMAN 1 1079.5611 1.82 42250 6403 2 1079.562674 540.7878 Rab-like protein 3 OS=Homo sapiens OX=9606 GN=RABL3 PE=1 SV=1 8.59 1734.8 - 231091 - - - 1.4358 - 1.162 0.238 - 106.8 1 2 0 0.0015 11 0 0 0 4.53E+07 2.49E+07 - - - 1.2046 0.9993 221125_WJC_METTL3_EV_vs_WT_F04.06407.06407.2 0.00555 14-Aug R.AELDEVNK[136.11].S sp|Q03252|LMNB2_HUMAN 1 924.4644 1.48 42252 6407 2 924.46419 463.2395 Lamin-B2 OS=Homo sapiens OX=9606 GN=LMNB2 PE=1 SV=4 4.14 1735.3 - 1.66E+06 - - - -0.2012 - 1.645 0.3 - 287.3 1 2 0 -0.0002 8 0 0 0 5.77E+07 3.90E+07 - - - 2.7579 0.9982 221125_WJC_METTL3_EV_vs_WT_F04.06408.06408.2 0.0471 18-Sep R.VAASTQPLGR[166.11].L sp|Q8ND24|RN214_HUMAN 1 1008.5592 2.03 42253 6408 2 1008.559763 505.2869 RING finger protein 214 OS=Homo sapiens OX=9606 GN=RNF214 PE=1 SV=2 9.72 1735.4 - 998633 - - - 0.5949 - 1.793 0.173 - 305.6 1 2 0 0.0006 10 0 0 0 1.19E+08 5.87E+07 - - - 1.9484 0.9925 221125_WJC_METTL3_EV_vs_WT_F04.06409.06409.2 0.034 14-Jul K.DSLYAQGK.R "sp|P83881|RL36A_HUMAN,tr|H0Y3V9|H0Y3V9_HUMAN,tr|H7BY91|H7BY91_HUMAN,tr|H0Y5B4|H0Y5B4_HUMAN,tr|J3KQN4|J3KQN4_HUMAN,tr|H7BZ11|H7BZ11_HUMAN" 6 880.429 0.85 42254 6409 2 880.425968 441.2218 60S ribosomal protein L36a OS=Homo sapiens OX=9606 GN=RPL36A PE=1 SV=2 5.83 1735.5 - 594954 - - - -3.4972 - 1.437 0.285 - 171.2 1 2 0 -0.0031 8 0 0 0 1.19E+08 1.40E+08 - - - 2.2385 0.9987 221125_WJC_METTL3_EV_vs_WT_F04.06410.06410.2 0.0166 16-Jun R.FVDPNTQEK.V "sp|P58107|EPIPL_HUMAN,tr|A0A075B730|A0A075B730_HUMAN" 2 1076.5138 1.83 42255 6410 2 1076.514753 539.2642 Epiplakin OS=Homo sapiens OX=9606 GN=EPPK1 PE=1 SV=3 4.37 1735.6 - 346696 - - - 0.849 - 1.051 0.422 - 73.1 1 2 0 0.0009 9 0 0 0 2.11E+07 1.15E+07 - - - 2.3015 0.7938 221125_WJC_METTL3_EV_vs_WT_F04.06411.06411.2 0.337 12-Jul V.SETLSVR.T sp|Q9UNS1|TIM_HUMAN 1 790.4185 1.87 42256 6411 2 790.418764 396.2165 Protein timeless homolog OS=Homo sapiens OX=9606 GN=TIMELESS PE=1 SV=2 5.72 1735.8 - 267576 - - - 0.3568 - 1.282 0.192 - 213.7 1 1 0 0.0003 7 0 0 0 7.11E+06 3.81E+06 - - - 1.2462 0.8089 221125_WJC_METTL3_EV_vs_WT_F04.06414.06414.2 0.376 14-Jun T.FESPADAK[136.11].A "sp|O75526|RMXL2_HUMAN,sp|Q96E39|RMXL1_HUMAN,sp|Q8N7X1|RMXL3_HUMAN,sp|P38159|RBMX_HUMAN,tr|A0A1B0GUK8|A0A1B0GUK8_HUMAN,tr|H3BT71|H3BT71_HUMAN,tr|H0Y6E7|H0Y6E7_HUMAN,tr|H3BR27|H3BR27_HUMAN" 8 871.4167 1.89 42257 6414 2 871.415369 436.7156 "RNA-binding motif protein, X-linked-like-2 OS=Homo sapiens OX=9606 GN=RBMXL2 PE=1 SV=3" 4.37 1736.2 - 1.04E+06 - - - -1.5251 - 1.346 0.228 - 99.8 1 1 0 -0.0013 8 0 0 0 2.23E+08 1.18E+08 - - - 1.6207 0.9996 221125_WJC_METTL3_EV_vs_WT_F04.06415.06415.2 5.25E-06 18-Oct R.AEAALEEESR.Q "sp|Q969G3|SMCE1_HUMAN,tr|A0A2R8Y855|A0A2R8Y855_HUMAN,tr|A0A2R8YES3|A0A2R8YES3_HUMAN,tr|A0A2U3TZQ7|A0A2U3TZQ7_HUMAN,tr|A0A2R8Y7U4|A0A2R8Y7U4_HUMAN,tr|B4DGM3|B4DGM3_HUMAN,tr|A0A2R8YD78|A0A2R8YD78_HUMAN,tr|J3QKS7|J3QKS7_HUMAN,tr|A0A2R8Y4T4|A0A2R8Y4T4_HUMAN,tr|A0A2R8Y7I9|A0A2R8Y7I9_HUMAN,tr|J3QR61|J3QR61_HUMAN,tr|A0A2R8Y765|A0A2R8Y765_HUMAN,tr|J3KT85|J3KT85_HUMAN" 13 1103.5095 2.79 42258 6415 2 1103.507685 552.762 SWI\SNF-related matrix-associated actin-dependent regulator of chromatin subfamily E member 1 OS=Homo sapiens OX=9606 GN=SMARCE1 PE=1 SV=2 4.09 1736.4 - 729581 - - - -1.6284 - 2.202 0.363 - 495.8 1 2 0 -0.0018 10 0 0 0 6.94E+07 2.48E+07 - - - 3.9249 0.9984 221125_WJC_METTL3_EV_vs_WT_F04.06422.06422.2 0.00956 16-Jul R.EYTAAVEAK.Q "sp|Q99623|PHB2_HUMAN,tr|F5H3X6|F5H3X6_HUMAN,tr|A0A7I2V5F0|A0A7I2V5F0_HUMAN,tr|U3KPZ5|U3KPZ5_HUMAN,tr|F5GWA7|F5GWA7_HUMAN,tr|J3KPX7|J3KPX7_HUMAN,tr|F5GY37|F5GY37_HUMAN" 7 980.4815 0.78 42262 6422 2 980.478834 491.248 Prohibitin-2 OS=Homo sapiens OX=9606 GN=PHB2 PE=1 SV=2 4.53 1737.2 - 543369 - - - -2.6946 - 1.687 0.346 - 236 1 2 0 -0.0026 9 0 0 0 3.90E+08 5.02E+08 - - - 3.1087 0.9998 221125_WJC_METTL3_EV_vs_WT_F04.06426.06426.2 0.00864 18-Nov R.GAEQLAEGGR[166.11].M sp|Q08J23|NSUN2_HUMAN 1 996.4864 0.89 42264 6426 2 996.485778 499.2505 RNA cytosine C(5)-methyltransferase NSUN2 OS=Homo sapiens OX=9606 GN=NSUN2 PE=1 SV=2 4.53 1737.7 - 3.52E+06 - - - -0.6162 - 2.162 0.409 - 681.2 1 2 0 -0.0006 10 0 0 0 8.99E+07 1.01E+08 - - - 4.2139 0.9838 221125_WJC_METTL3_EV_vs_WT_F04.06433.06433.2 2.19 14-Jun R.GPGPLQER.S "sp|P43243|MATR3_HUMAN,tr|A8MXP9|A8MXP9_HUMAN,tr|D6R991|D6R991_HUMAN,tr|A0A0R4J2E8|A0A0R4J2E8_HUMAN,tr|H0Y8T4|H0Y8T4_HUMAN,tr|D6REM6|D6REM6_HUMAN" 6 852.4454 1.3 42269 6433 2 852.44488 427.23 Matrin-3 OS=Homo sapiens OX=9606 GN=MATR3 PE=1 SV=2 6 1738.6 - 1.09E+06 - - - -0.5701 - 1.262 0.097 - 130 2 2 0 -0.0005 8 0 0 0 3.73E+09 2.88E+09 - - - 0.3246 0.9983 221125_WJC_METTL3_EV_vs_WT_F04.06438.06438.2 0.0302 16-Aug K.TLNAGAYSK.V "sp|P50897|PPT1_HUMAN,tr|Q5T0S4|Q5T0S4_HUMAN,tr|A0A286YFL6|A0A286YFL6_HUMAN,tr|A0A2C9F2P4|A0A2C9F2P4_HUMAN,tr|A0A286YFL8|A0A286YFL8_HUMAN,tr|A0A286YFF7|A0A286YFF7_HUMAN,tr|A0A286YFE3|A0A286YFE3_HUMAN" 7 923.4712 1.8 42272 6438 2 923.472443 462.7429 Palmitoyl-protein thioesterase 1 OS=Homo sapiens OX=9606 GN=PPT1 PE=1 SV=1 8.26 1739.2 - 890779 - - - 1.2962 - 1.399 0.306 - 188.4 1 2 0 0.0012 9 0 0 0 7.48E+07 4.15E+07 - - - 2.2721 0.9989 221125_WJC_METTL3_EV_vs_WT_F04.06441.06441.2 0.00304 16-Sep R.VAVLENQNK[136.11].T "sp|P16220|CREB1_HUMAN,sp|P18846|ATF1_HUMAN,tr|G5E998|G5E998_HUMAN,tr|E9PAR2|E9PAR2_HUMAN" 4 1021.5648 0.73 42275 6441 2 1021.564749 511.7897 Cyclic AMP-responsive element-binding protein 1 OS=Homo sapiens OX=9606 GN=CREB1 PE=1 SV=3 5.97 1739.6 - 498457 - - - -0.0098 - 1.962 0.18 - 307.9 1 2 0 0 9 0 0 0 5.44E+07 7.45E+07 - - - 2.3203 0.8064 221125_WJC_METTL3_EV_vs_WT_F04.06444.06444.2 0.0235 16-Jul A.PGSPPLSPR[166.11].G sp|Q86UU0|BCL9L_HUMAN 1 916.5006 0.13 42276 6444 2 916.498755 459.2576 B-cell CLL\lymphoma 9-like protein OS=Homo sapiens OX=9606 GN=BCL9L PE=1 SV=1 10.18 1739.9 - 1.86E+06 - - - -1.9978 - 1.334 0.268 - 91 1 1 0 -0.0018 9 0 0 0 7.72E+06 5.76E+07 - - - 1.8536 0.9977 221125_WJC_METTL3_EV_vs_WT_F04.06445.06445.2 0.208 12-Jun K.LAEPYGK[136.11].L "sp|P43243|MATR3_HUMAN,tr|B3KM87|B3KM87_HUMAN,tr|A8MXP9|A8MXP9_HUMAN,tr|D6RBK5|D6RBK5_HUMAN,tr|A0A0R4J2E8|A0A0R4J2E8_HUMAN,tr|H0Y8T4|H0Y8T4_HUMAN,tr|D6REM6|D6REM6_HUMAN" 7 784.4211 1.27 42277 6445 2 784.421311 393.2178 Matrin-3 OS=Homo sapiens OX=9606 GN=MATR3 PE=1 SV=2 6 1740 - 924302 - - - 0.3264 - 1.278 0.257 - 141.7 1 2 0 0.0003 7 0 0 0 2.19E+08 1.72E+08 - - - 1.7164 0.9993 221125_WJC_METTL3_EV_vs_WT_F04.06446.06446.2 0.403 12-Oct R.VAHLALK[136.11].H "sp|P55036|PSMD4_HUMAN,sp|A2A3N6|PIPSL_HUMAN,tr|A6PVX3|A6PVX3_HUMAN,tr|Q5VWC4|Q5VWC4_HUMAN" 4 758.4894 0.001 42278 6446 2 758.489607 380.252 26S proteasome non-ATPase regulatory subunit 4 OS=Homo sapiens OX=9606 GN=PSMD4 PE=1 SV=1 8.73 1740.2 - 448828 - - - 0.261 - 1.837 0.246 - 411.8 1 2 0 0.0002 7 0 0 0 0.00E+00 9.96E+06 - - - 2.7848 0.9972 221125_WJC_METTL3_EV_vs_WT_F04.06447.06447.2 0.0565 16-Oct R.VAVLENQNK.T "sp|P16220|CREB1_HUMAN,sp|P18846|ATF1_HUMAN,tr|G5E998|G5E998_HUMAN,tr|E9PAR2|E9PAR2_HUMAN" 4 1013.5506 0.7 42279 6447 2 1013.55263 507.7826 Cyclic AMP-responsive element-binding protein 1 OS=Homo sapiens OX=9606 GN=CREB1 PE=1 SV=3 5.97 1740.3 - 426526 - - - 2.0433 - 1.816 0.196 - 362.6 1 2 0 0.0021 9 0 0 0 5.18E+07 7.44E+07 - - - 2.2141 0.9954 221125_WJC_METTL3_EV_vs_WT_F04.06450.06450.2 0.0802 18-Aug R.VAASTQPLGR.L sp|Q8ND24|RN214_HUMAN 1 998.5509 1.97 42280 6450 2 998.548999 500.2827 RING finger protein 214 OS=Homo sapiens OX=9606 GN=RNF214 PE=1 SV=2 9.72 1740.7 - 2.86E+06 - - - -1.8967 - 1.717 0.154 - 251.9 1 2 0 -0.0019 10 0 0 0 1.20E+08 6.10E+07 - - - 1.6868 0.9972 221125_WJC_METTL3_EV_vs_WT_F04.06451.06451.2 1.76 12-Jul K.LAEPYGK.L "sp|P43243|MATR3_HUMAN,tr|B3KM87|B3KM87_HUMAN,tr|A8MXP9|A8MXP9_HUMAN,tr|D6RBK5|D6RBK5_HUMAN,tr|A0A0R4J2E8|A0A0R4J2E8_HUMAN,tr|H0Y8T4|H0Y8T4_HUMAN,tr|D6REM6|D6REM6_HUMAN" 7 776.4069 1.27 42281 6451 2 776.406519 389.2107 Matrin-3 OS=Homo sapiens OX=9606 GN=MATR3 PE=1 SV=2 6 1740.8 - 1.30E+06 - - - -0.4328 - 1.219 0.255 - 181.2 1 2 0 -0.0003 7 0 0 0 2.19E+08 1.72E+08 - - - 1.5518 0.9636 221125_WJC_METTL3_EV_vs_WT_F04.06457.06457.2 7.11 14-Jun R.ELAQQIQK[136.11].V "sp|Q14240|IF4A2_HUMAN,sp|P60842|IF4A1_HUMAN,tr|J3KTB5|J3KTB5_HUMAN,tr|J3KT12|J3KT12_HUMAN,tr|J3QKZ9|J3QKZ9_HUMAN,tr|J3QL43|J3QL43_HUMAN,tr|E7EQG2|E7EQG2_HUMAN,tr|J3KS25|J3KS25_HUMAN,tr|J3QLN6|J3QLN6_HUMAN,tr|J3QR64|J3QR64_HUMAN,tr|J3KSN7|J3KSN7_HUMAN" 11 964.5433 1.54 42283 6457 2 964.542885 483.2789 Eukaryotic initiation factor 4A-II OS=Homo sapiens OX=9606 GN=EIF4A2 PE=1 SV=2 6.1 1741.6 - 926507 - - - -0.4251 - 1.108 0.058 - 85.1 1 2 0 -0.0004 8 0 0 0 1.33E+08 8.69E+07 - - - -0.2214 0.9992 221125_WJC_METTL3_EV_vs_WT_F04.06461.06461.2 0.00508 18-Oct K.IGDVSSSAVK.T sp|Q9BYJ9|YTHD1_HUMAN 1 961.508 1.95 42284 6461 2 961.506293 481.7613 YTH domain-containing family protein 1 OS=Homo sapiens OX=9606 GN=YTHDF1 PE=1 SV=1 5.84 1742.2 - 1.41E+06 - - - -1.8024 - 1.983 0.307 - 193 1 2 0 -0.0017 10 0 0 0 4.51E+08 2.31E+08 - - - 3.2189 0.9974 221125_WJC_METTL3_EV_vs_WT_F04.06466.06466.2 0.252 16-Aug R.AISSSAISR.A "sp|Q16630|CPSF6_HUMAN,tr|F8WJN3|F8WJN3_HUMAN" 2 890.4821 0.12 42285 6466 2 890.482033 446.2483 Cleavage and polyadenylation specificity factor subunit 6 OS=Homo sapiens OX=9606 GN=CPSF6 PE=1 SV=2 9.79 1742.9 - 1.52E+06 - - - -0.1258 - 1.302 0.241 - 125.5 1 2 0 -0.0001 9 0 0 0 3.77E+07 3.20E+08 - - - 1.5845 0.9996 221125_WJC_METTL3_EV_vs_WT_F04.06468.06468.2 0.00246 14-Aug R.LETYENAR.K sp|O94906|PRP6_HUMAN 1 994.472 3.04 42287 6468 2 994.470704 498.2433 Pre-mRNA-processing factor 6 OS=Homo sapiens OX=9606 GN=PRPF6 PE=1 SV=1 4.53 1743.1 - 2.13E+06 - - - -1.2771 - 1.66 0.424 - 252 1 2 0 -0.0013 8 0 0 0 2.26E+08 7.43E+07 - - - 3.7008 0.967 221125_WJC_METTL3_EV_vs_WT_F04.06472.06472.2 0.349 12-Jul R.SVDETLR[166.11].L "sp|Q06830|PRDX1_HUMAN,sp|Q13162|PRDX4_HUMAN,tr|A0A0A0MRQ5|A0A0A0MRQ5_HUMAN,tr|H7C3T4|H7C3T4_HUMAN,tr|A0A0A0MSI0|A0A0A0MSI0_HUMAN" 5 828.4217 0.67 42289 6472 2 828.419679 415.2181 Peroxiredoxin-1 OS=Homo sapiens OX=9606 GN=PRDX1 PE=1 SV=1 4.37 1743.5 - 6.79E+06 - - - -2.3997 - 1.352 0.07 - 144.2 1 2 0 -0.002 7 0 0 0 1.57E+08 2.35E+08 - - - 0.513 0.9993 221125_WJC_METTL3_EV_vs_WT_F04.06473.06473.2 0.108 14-Aug R.FSNISAAK.A "sp|P50991|TCPD_HUMAN,sp|P05543|THBG_HUMAN" 2 836.4392 0.32 42290 6473 2 836.438343 419.2269 T-complex protein 1 subunit delta OS=Homo sapiens OX=9606 GN=CCT4 PE=1 SV=4 8.75 1743.6 - 2.31E+06 - - - -1.0461 - 1.653 0.311 - 136.3 1 2 0 -0.0009 8 0 0 0 8.34E+08 2.63E+09 - - - 2.8536 0.9968 221125_WJC_METTL3_EV_vs_WT_F04.06474.06474.2 0.0717 14-Jun R.LETYENAR[166.11].K sp|O94906|PRP6_HUMAN 1 1004.4802 2.93 42291 6474 2 1004.480578 503.2474 Pre-mRNA-processing factor 6 OS=Homo sapiens OX=9606 GN=PRPF6 PE=1 SV=1 4.53 1743.7 - 1.16E+06 - - - 0.3325 - 1.359 0.204 - 120.1 1 2 0 0.0003 8 0 0 0 2.02E+08 6.90E+07 - - - 1.4728 0.997 221125_WJC_METTL3_EV_vs_WT_F04.06478.06478.2 0.147 14-Jul R.AQVVSNLK[136.11].G sp|Q9Y490|TLN1_HUMAN 1 865.5113 0.33 42293 6478 2 865.510365 433.7629 Talin-1 OS=Homo sapiens OX=9606 GN=TLN1 PE=1 SV=3 8.8 1744.2 - 1.25E+06 - - - -1.0422 - 1.473 0.193 - 140.3 1 2 0 -0.0009 8 0 0 0 9.69E+06 2.93E+07 - - - 1.6343 0.9889 221125_WJC_METTL3_EV_vs_WT_F04.06480.06480.2 0.286 16-Jul R.VESAEIEER[166.11].E "sp|Q06547|GABP1_HUMAN,tr|F5H7I4|F5H7I4_HUMAN" 2 1070.5119 2.75 42295 6480 2 1070.509063 536.2632 GA-binding protein subunit beta-1 OS=Homo sapiens OX=9606 GN=GABPB1 PE=1 SV=2 4.09 1744.5 - 252683 - - - -2.6856 - 1.438 0.183 - 141.9 1 2 0 -0.0029 9 0 0 0 3.79E+07 1.38E+07 - - - 1.4426 0.9979 221125_WJC_METTL3_EV_vs_WT_F04.06485.06485.2 0.242 14-Aug R.GPGPLQER[166.11].S "sp|P43243|MATR3_HUMAN,tr|A8MXP9|A8MXP9_HUMAN,tr|D6R991|D6R991_HUMAN,tr|A0A0R4J2E8|A0A0R4J2E8_HUMAN,tr|H0Y8T4|H0Y8T4_HUMAN,tr|D6REM6|D6REM6_HUMAN" 6 862.4536 1.3 42298 6485 2 862.453259 432.2341 Matrin-3 OS=Homo sapiens OX=9606 GN=MATR3 PE=1 SV=2 6 1745 - 5.73E+06 - - - -0.4371 - 1.424 0.224 - 263.2 1 2 0 -0.0004 8 0 0 0 3.88E+09 2.99E+09 - - - 1.7614 0.9732 221125_WJC_METTL3_EV_vs_WT_F04.06502.06502.2 5.18 18-Jul R.YLADQNNQVR[166.11].K "sp|Q8TF05|PP4R1_HUMAN,tr|J3QQV0|J3QQV0_HUMAN,tr|J3KSB0|J3KSB0_HUMAN,tr|J3QL26|J3QL26_HUMAN,tr|J3QLA6|J3QLA6_HUMAN" 5 1229.6028 0.39 42304 6502 2 1229.602844 615.8087 Serine\threonine-protein phosphatase 4 regulatory subunit 1 OS=Homo sapiens OX=9606 GN=PPP4R1 PE=1 SV=1 5.84 1747.4 - 143892 - - - 0.0203 - 1.173 0.065 - 145.4 1 2 0 0 10 0 0 0 1.01E+06 2.59E+06 - - - -0.0335 0.9982 221125_WJC_METTL3_EV_vs_WT_F04.06506.06506.2 0.393 14-Aug K.VSEDEELR.K "sp|Q9Y2W6|TDRKH_HUMAN,tr|F6TB26|F6TB26_HUMAN,tr|Q5SZR4|Q5SZR4_HUMAN" 3 975.4509 1.41 42306 6506 2 975.450117 488.7327 Tudor and KH domain-containing protein OS=Homo sapiens OX=9606 GN=TDRKH PE=1 SV=2 4 1747.8 - 565911 - - - -0.8078 - 1.64 0.193 - 219.3 1 2 0 -0.0008 8 0 0 0 5.97E+07 4.23E+07 - - - 1.9582 0.9974 221125_WJC_METTL3_EV_vs_WT_F04.06508.06508.2 3.24 14-Aug R.IEEELGSK.A "sp|P06733|ENOA_HUMAN,tr|A0A2R8Y6G6|A0A2R8Y6G6_HUMAN" 2 903.4549 1.48 42307 6508 2 903.454937 452.7347 Alpha-enolase OS=Homo sapiens OX=9606 GN=ENO1 PE=1 SV=2 4.25 1748.1 - 1.69E+07 - - - 0.0111 - 1.292 0.241 - 139 1 2 0 0 8 0 0 0 1.42E+09 9.58E+08 - - - 1.5937 0.9908 221125_WJC_METTL3_EV_vs_WT_F04.06513.06513.2 0.513 14-Jun R.VISSIEQK.T "sp|P31946|1433B_HUMAN,sp|P27348|1433T_HUMAN,sp|Q04917|1433F_HUMAN,sp|P31947|1433S_HUMAN,sp|P61981|1433G_HUMAN,tr|Q4VY19|Q4VY19_HUMAN,tr|A0A0J9YWZ2|A0A0J9YWZ2_HUMAN,tr|Q4VY20|Q4VY20_HUMAN,tr|A2IDB2|A2IDB2_HUMAN,tr|E9PG15|E9PG15_HUMAN,tr|A0A0J9YWE8|A0A0J9YWE8_HUMAN" 11 902.5073 0.99 42310 6513 2 902.506669 452.2609 14-3-3 protein beta\alpha OS=Homo sapiens OX=9606 GN=YWHAB PE=1 SV=3 5.97 1748.6 - 1.46E+07 - - - -0.6958 - 1.126 0.198 - 72.2 2 2 0 -0.0006 8 0 0 0 4.49E+08 4.55E+08 - - - 0.7267 0.9998 221125_WJC_METTL3_EV_vs_WT_F04.06514.06514.2 0.00497 20-Jul K.EMDEAATAEER.G "sp|Q04637|IF4G1_HUMAN,tr|E7EUU4|E7EUU4_HUMAN,tr|E9PGM1|E9PGM1_HUMAN,tr|C9J6B6|C9J6B6_HUMAN,tr|E7EX73|E7EX73_HUMAN,tr|A0A7I2Y1C3|A0A7I2Y1C3_HUMAN,tr|C9JF13|C9JF13_HUMAN" 7 1250.5085 0.8 42311 6514 2 1250.508049 626.2615 Eukaryotic translation initiation factor 4 gamma 1 OS=Homo sapiens OX=9606 GN=EIF4G1 PE=1 SV=4 3.91 1748.8 - 240539 - - - -0.3575 - 1.606 0.493 - 226.6 1 2 0 -0.0004 11 0 0 0 4.01E+06 4.98E+06 - - - 3.9638 0.9995 221125_WJC_METTL3_EV_vs_WT_F04.06515.06515.2 0.0264 20-Oct R.LSGGLGAGSC[160.03]R.L "sp|Q04695|K1C17_HUMAN,tr|K7EPJ9|K7EPJ9_HUMAN" 2 1033.4975 3045.14 42312 6515 2 1033.495212 517.756 "Keratin, type I cytoskeletal 17 OS=Homo sapiens OX=9606 GN=KRT17 PE=1 SV=2" 8.25 1748.8 - 1.68E+06 - - - -2.1926 - 2.126 0.401 - 293.1 1 2 0 -0.0023 11 0 0 0 6.22E+09 2.04E+06 - - - 4.0425 0.9996 221125_WJC_METTL3_EV_vs_WT_F04.06518.06518.2 0.0032 16-Aug K.QVDPAYTGR[166.11].V "sp|Q9UBC2|EP15R_HUMAN,tr|M0QX30|M0QX30_HUMAN,tr|K7EJR2|K7EJR2_HUMAN,tr|M0R1V5|M0R1V5_HUMAN,tr|M0R330|M0R330_HUMAN,tr|M0R165|M0R165_HUMAN" 6 1015.4962 1.75 42313 6518 2 1015.496151 508.7554 Epidermal growth factor receptor substrate 15-like 1 OS=Homo sapiens OX=9606 GN=EPS15L1 PE=1 SV=1 5.84 1749.2 - 500973 - - - -0.0768 - 1.708 0.347 - 258.8 1 2 0 -0.0001 9 0 0 0 5.38E+07 3.07E+07 - - - 3.1526 0.9979 221125_WJC_METTL3_EV_vs_WT_F04.06519.06519.2 4.16E-05 20-Sep K.EMDEAATAEER[166.11].G "sp|Q04637|IF4G1_HUMAN,tr|E7EUU4|E7EUU4_HUMAN,tr|E9PGM1|E9PGM1_HUMAN,tr|C9J6B6|C9J6B6_HUMAN,tr|E7EX73|E7EX73_HUMAN,tr|A0A7I2Y1C3|A0A7I2Y1C3_HUMAN,tr|C9JF13|C9JF13_HUMAN" 7 1260.5168 0.8 42314 6519 2 1260.51035 631.2657 Eukaryotic translation initiation factor 4 gamma 1 OS=Homo sapiens OX=9606 GN=EIF4G1 PE=1 SV=4 3.91 1749.4 - 234885 - - - -5.09 - 1.994 0.572 - 240.7 1 2 0 -0.0064 11 0 0 0 4.01E+06 4.98E+06 - - - 5.1308 0.9901 221125_WJC_METTL3_EV_vs_WT_F04.06526.06526.2 1.13 12-Jul K.YGTDLSR.G "sp|P05023|AT1A1_HUMAN,tr|Q5TC01|Q5TC01_HUMAN,tr|Q5TC02|Q5TC02_HUMAN" 3 810.3872 1.17 42318 6526 2 810.38736 406.2009 Sodium\potassium-transporting ATPase subunit alpha-1 OS=Homo sapiens OX=9606 GN=ATP1A1 PE=1 SV=1 5.84 1750.2 - 545675 - - - 0.2196 - 1.354 0.087 - 146.4 1 2 0 0.0002 7 0 0 0 1.57E+07 1.35E+07 - - - 0.6438 0.9979 221125_WJC_METTL3_EV_vs_WT_F04.06530.06530.2 1.72 16-Sep K.SAVEDEGLK[136.11].G "sp|P0DMV8|HS71A_HUMAN,sp|P0DMV9|HS71B_HUMAN,tr|V9GZ37|V9GZ37_HUMAN,tr|A0A0G2JIW1|A0A0G2JIW1_HUMAN" 4 954.4749 0.15 42320 6530 2 954.475814 478.2447 Heat shock 70 kDa protein 1A OS=Homo sapiens OX=9606 GN=HSPA1A PE=1 SV=1 4.14 1750.8 - 5.25E+06 - - - 0.9146 - 1.825 0.156 - 300.1 1 2 0 0.0009 9 0 0 0 4.18E+09 2.73E+10 - - - 1.9333 0.9997 221125_WJC_METTL3_EV_vs_WT_F04.06533.06533.2 0.0171 16-Oct K.VYQETSEMR[166.11].S "sp|Q15773|MLF2_HUMAN,tr|F5H0Y3|F5H0Y3_HUMAN" 2 1151.5156 3.34 42322 6533 2 1151.515502 576.7651 Myeloid leukemia factor 2 OS=Homo sapiens OX=9606 GN=MLF2 PE=1 SV=1 4.53 1751.1 - 738256 - - - -0.1233 - 1.548 0.434 - 154.6 1 2 0 -0.0001 9 0 0 0 9.29E+07 2.78E+07 - - - 3.5106 0.9998 221125_WJC_METTL3_EV_vs_WT_F04.06534.06534.2 0.0003 18-Nov K.GSAITGPVAK[136.11].E "sp|P62829|RL23_HUMAN,tr|J3KTJ3|J3KTJ3_HUMAN" 2 907.5218 1.04 42323 6534 2 907.521098 454.7682 60S ribosomal protein L23 OS=Homo sapiens OX=9606 GN=RPL23 PE=1 SV=1 8.75 1751.1 - 8.87E+06 - - - -0.8088 - 1.828 0.456 - 475 1 2 0 -0.0007 10 0 0 0 9.06E+09 8.72E+09 - - - 4.0926 0.9995 221125_WJC_METTL3_EV_vs_WT_F04.06539.06539.2 0.00154 18-Sep K.GSAITGPVAK.E "sp|P62829|RL23_HUMAN,tr|J3KTJ3|J3KTJ3_HUMAN" 2 899.5076 1.04 42326 6539 2 899.507183 450.7611 60S ribosomal protein L23 OS=Homo sapiens OX=9606 GN=RPL23 PE=1 SV=1 8.75 1751.7 - 1.20E+07 - - - -0.4992 - 1.604 0.368 - 245.8 1 2 0 -0.0004 10 0 0 0 9.06E+09 8.72E+09 - - - 3.0778 0.9996 221125_WJC_METTL3_EV_vs_WT_F04.06542.06542.2 0.338 20-Aug R.DPAATSVAAAR.K "sp|O00762|UBE2C_HUMAN,tr|K4DI81|K4DI81_HUMAN,tr|A0A087WVK1|A0A087WVK1_HUMAN,tr|A0A0A0MSE8|A0A0A0MSE8_HUMAN" 4 1028.5251 0.56 42329 6542 2 1028.525235 515.2698 Ubiquitin-conjugating enzyme E2 C OS=Homo sapiens OX=9606 GN=UBE2C PE=1 SV=1 5.84 1752 - 383419 - - - 0.1575 - 2.003 0.316 - 208.7 1 2 0 0.0002 11 0 0 0 1.06E+07 1.89E+07 - - - 3.2541 0.9994 221125_WJC_METTL3_EV_vs_WT_F04.06547.06547.2 0.000911 14-Sep K.SPGFASPK[136.11].L sp|P49790|NU153_HUMAN 1 797.4163 1.47 42332 6547 2 797.415317 399.7154 Nuclear pore complex protein Nup153 OS=Homo sapiens OX=9606 GN=NUP153 PE=1 SV=2 8.47 1752.6 - 1.16E+06 - - - -1.2377 - 1.57 0.38 - 227.5 1 2 0 -0.001 8 0 0 0 2.47E+08 1.68E+08 - - - 3.2078 0.9681 221125_WJC_METTL3_EV_vs_WT_F04.06551.06551.2 4.08 16-Jun R.AAVPDAVGK.C "sp|P05023|AT1A1_HUMAN,sp|P13637|AT1A3_HUMAN,sp|P50993|AT1A2_HUMAN,tr|A0A0A0MT26|A0A0A0MT26_HUMAN,tr|H0Y7C1|H0Y7C1_HUMAN,tr|A0A2R8YEY8|A0A2R8YEY8_HUMAN,tr|B1AKY9|B1AKY9_HUMAN,tr|M0R116|M0R116_HUMAN" 8 826.4549 1.01 42334 6551 2 826.455663 414.2347 Sodium\potassium-transporting ATPase subunit alpha-1 OS=Homo sapiens OX=9606 GN=ATP1A1 PE=1 SV=1 5.88 1753.1 - 1.91E+06 - - - 0.9619 - 1.106 0.122 - 82.6 3 2 0 0.0008 9 0 0 0 8.69E+07 8.62E+07 - - - 0.0202 0.9827 221125_WJC_METTL3_EV_vs_WT_F04.06553.06553.2 0.947 12-Jul K.ISIEGNK.M sp|Q96ST2|IWS1_HUMAN 1 759.4127 0.87 42335 6553 2 759.412009 380.7136 Protein IWS1 homolog OS=Homo sapiens OX=9606 GN=IWS1 PE=1 SV=2 6 1753.3 - 422680 - - - -0.8691 - 1.453 0.015 - 128.5 1 2 0 -0.0007 7 0 0 0 2.07E+07 2.37E+07 - - - 0.3355 0.9983 221125_WJC_METTL3_EV_vs_WT_F04.06554.06554.2 0.027 18-Jul K.LTQDQDVDVK[136.11].Y "sp|P30153|2AAA_HUMAN,tr|E9PH38|E9PH38_HUMAN,tr|B3KQV6|B3KQV6_HUMAN" 3 1167.5863 1.4 42336 6554 2 1167.585978 584.8004 Serine\threonine-protein phosphatase 2A 65 kDa regulatory subunit A alpha isoform OS=Homo sapiens OX=9606 GN=PPP2R1A PE=1 SV=4 3.93 1753.5 - 188109 - - - -0.2604 - 1.28 0.297 - 101.7 1 2 0 -0.0003 10 0 0 0 7.64E+06 5.46E+06 - - - 1.9236 0.9793 221125_WJC_METTL3_EV_vs_WT_F04.06555.06555.2 0.133 18-Jun R.DPAGEAVDPR.K sp|Q9NUD5|ZCHC3_HUMAN 1 1025.4778 1.37 42337 6555 2 1025.479992 513.7462 Zinc finger CCHC domain-containing protein 3 OS=Homo sapiens OX=9606 GN=ZCCHC3 PE=1 SV=2 4.03 1753.6 - 585932 - - - 2.1492 - 1.216 0.158 - 109.1 1 2 0 0.0022 10 0 0 0 6.71E+07 4.91E+07 - - - 0.7532 0.9914 221125_WJC_METTL3_EV_vs_WT_F04.06560.06560.2 0.0355 12-Aug K.VREYELR.K "sp|P62913|RL11_HUMAN,tr|Q5VVC8|Q5VVC8_HUMAN" 2 963.5138 1.82 42340 6560 2 963.511683 482.7642 60S ribosomal protein L11 OS=Homo sapiens OX=9606 GN=RPL11 PE=1 SV=2 6.11 1754.2 - 2.91E+06 - - - -2.1764 - 1.901 0.33 - 236 1 2 1 -0.0021 7 0 0 0 1.31E+08 7.22E+07 - - - 3.5131 0.9939 221125_WJC_METTL3_EV_vs_WT_F04.06561.06561.2 0.796 12-Sep R.R[166.11]FVEVGR[166.11].V "sp|P50914|RL14_HUMAN,tr|E7EPB3|E7EPB3_HUMAN" 2 881.4986 0.07 42341 6561 2 881.496918 441.7566 60S ribosomal protein L14 OS=Homo sapiens OX=9606 GN=RPL14 PE=1 SV=4 9.6 1754.3 - 971046 - - - -1.9376 - 1.466 0.167 - 194.3 1 2 0 -0.0017 7 0 0 0 6.83E+06 9.84E+07 - - - 1.486 0.9988 221125_WJC_METTL3_EV_vs_WT_F04.06563.06563.2 0.101 18-Aug K.LAGESESNLR.K "sp|P55072|TERA_HUMAN,tr|A0A7P0Z4C6|A0A7P0Z4C6_HUMAN,tr|A0A7I2V2Y2|A0A7I2V2Y2_HUMAN,tr|A0A7P0T8Q5|A0A7P0T8Q5_HUMAN,tr|C9JUP7|C9JUP7_HUMAN,tr|A0A7P0TAW3|A0A7P0TAW3_HUMAN,tr|A0A7I2V540|A0A7I2V540_HUMAN,tr|A0A7P0T8A3|A0A7P0T8A3_HUMAN,tr|A0A7P0TAQ1|A0A7P0TAQ1_HUMAN,tr|A0A7I2V5G8|A0A7I2V5G8_HUMAN,tr|A0A7P0TAY0|A0A7P0TAY0_HUMAN" 11 1074.5306 1.29 42343 6563 2 1074.531083 538.2726 Transitional endoplasmic reticulum ATPase OS=Homo sapiens OX=9606 GN=VCP PE=1 SV=4 4.53 1754.6 - 398648 - - - 0.4942 - 1.783 0.225 - 192.9 1 2 0 0.0005 10 0 0 0 1.36E+08 1.05E+08 - - - 2.3169 0.9971 221125_WJC_METTL3_EV_vs_WT_F04.06567.06567.2 0.147 12-Jun R.QLEYNAR.N sp|Q13835|PKP1_HUMAN 1 892.4403 0.26 42345 6567 2 892.439766 447.2274 Plakophilin-1 OS=Homo sapiens OX=9606 GN=PKP1 PE=1 SV=2 6 1755 - 2.50E+06 - - - -0.5759 - 1.176 0.269 - 238.2 1 2 0 -0.0005 7 0 0 0 1.51E+08 5.91E+08 - - - 1.5414 0.9876 221125_WJC_METTL3_EV_vs_WT_F04.06573.06573.2 0.659 16-Apr R.YSMQGEEAR.A sp|P0C7T5|ATX1L_HUMAN 1 1069.4499 2.23 42348 6573 2 1069.449026 535.7322 Ataxin-1-like OS=Homo sapiens OX=9606 GN=ATXN1L PE=1 SV=1 4.53 1755.7 - 340654 - - - -0.7789 - 0.966 0.277 - 41.1 10 2 0 -0.0008 9 0 0 0 3.93E+06 1.77E+06 - - - 0.5399 0.9486 221125_WJC_METTL3_EV_vs_WT_F04.06579.06579.2 0.706 12-May R.FQTMEEK[136.11].K "sp|P39023|RL3_HUMAN,tr|G5E9G0|G5E9G0_HUMAN" 2 919.4201 0.84 42350 6579 2 919.418078 460.7173 60S ribosomal protein L3 OS=Homo sapiens OX=9606 GN=RPL3 PE=1 SV=2 4.53 1756.5 - 891628 - - - -2.1655 - 1.155 0.1 - 66.1 2 2 0 -0.002 7 0 0 0 5.55E+07 6.61E+07 - - - 0.1011 0.9999 221125_WJC_METTL3_EV_vs_WT_F04.06582.06582.2 0.000124 12-Jul R.MDYEDDR.L "sp|P43243|MATR3_HUMAN,tr|A8MXP9|A8MXP9_HUMAN,tr|D6R991|D6R991_HUMAN,tr|A0A0R4J2E8|A0A0R4J2E8_HUMAN,tr|D6REM6|D6REM6_HUMAN" 5 942.3389 1.67 42351 6582 2 942.338017 472.1767 Matrin-3 OS=Homo sapiens OX=9606 GN=MATR3 PE=1 SV=2 3.84 1756.9 - 1.19E+07 - - - -0.9487 - 1.631 0.629 - 285.7 1 2 0 -0.0009 7 0 0 0 3.46E+08 2.07E+08 - - - 5.2365 0.8487 221125_WJC_METTL3_EV_vs_WT_F04.06584.06584.2 0.28 14-Jun R.FSNISAAK[136.11].A "sp|P50991|TCPD_HUMAN,sp|P05543|THBG_HUMAN" 2 844.4534 0.31 42353 6584 2 844.448017 423.234 T-complex protein 1 subunit delta OS=Homo sapiens OX=9606 GN=CCT4 PE=1 SV=4 8.75 1757 - 3.63E+06 - - - -6.3959 - 1.335 0.226 - 68.8 3 2 0 -0.0054 8 0 0 0 8.45E+08 2.69E+09 - - - 1.3668 0.9926 221125_WJC_METTL3_EV_vs_WT_F04.06589.06589.2 0.0648 14-May K.YAYTGEC[160.03]R.S "sp|P30876|RPB2_HUMAN,tr|C9J4M6|C9J4M6_HUMAN,tr|C9J2Y9|C9J2Y9_HUMAN" 3 1018.4178 0.26 42355 6589 2 1018.414839 510.2162 DNA-directed RNA polymerase II subunit RPB2 OS=Homo sapiens OX=9606 GN=POLR2B PE=1 SV=1 5.99 1757.6 - 381564 - - - -2.9379 - 1.104 0.347 - 66.9 1 2 0 -0.003 8 0 0 0 1.51E+07 5.76E+07 - - - 1.9014 0.9714 221125_WJC_METTL3_EV_vs_WT_F04.06594.06594.2 0.00208 20-Dec R.LAGENMTGAAK[136.11].P "sp|O95831|AIFM1_HUMAN,tr|A0A6Q8PHJ9|A0A6Q8PHJ9_HUMAN,tr|A0A6Q8PFS4|A0A6Q8PFS4_HUMAN,tr|E9PMA0|E9PMA0_HUMAN,tr|A0A7I2PK44|A0A7I2PK44_HUMAN,tr|A0A6Q8PG15|A0A6Q8PG15_HUMAN,tr|A0A6Q8PFE1|A0A6Q8PFE1_HUMAN,tr|A0A6Q8PHJ4|A0A6Q8PHJ4_HUMAN,tr|A0A6Q8PFQ8|A0A6Q8PFQ8_HUMAN,tr|A0A6Q8PHC0|A0A6Q8PHC0_HUMAN,tr|A0A6Q8PFM5|A0A6Q8PFM5_HUMAN" 11 1069.5317 0.49 42357 6594 2 1069.530135 535.7731 "Apoptosis-inducing factor 1, mitochondrial OS=Homo sapiens OX=9606 GN=AIFM1 PE=1 SV=1" 6 1758.3 - 346836 - - - -1.5044 - 2.088 0.337 - 345.6 1 1 0 -0.0016 11 0 0 0 1.05E+07 2.14E+07 - - - 3.5212 0.9996 221125_WJC_METTL3_EV_vs_WT_F04.06599.06599.2 1.22E-06 18-Dec R.VGEAIETTQR.F "sp|Q6VN20|RBP10_HUMAN,tr|A0A0D9SEU5|A0A0D9SEU5_HUMAN,tr|R4GMX8|R4GMX8_HUMAN" 3 1102.5619 0.96 42358 6599 2 1102.559001 552.2882 Ran-binding protein 10 OS=Homo sapiens OX=9606 GN=RANBP10 PE=1 SV=1 4.53 1759.1 - 655466 - - - -2.5858 - 2.34 0.444 - 757 1 2 0 -0.0029 10 0 0 0 2.25E+07 2.33E+07 - - - 4.6925 0.993 221125_WJC_METTL3_EV_vs_WT_F04.06601.06601.2 0.347 16-Jul K.SLQPAVAEK.Q "sp|P35658|NU214_HUMAN,tr|A0A0A0MSW3|A0A0A0MSW3_HUMAN,tr|A0A494BZU9|A0A494BZU9_HUMAN,tr|A0A494C1F2|A0A494C1F2_HUMAN" 4 941.5182 2.12 42359 6601 2 941.516907 471.7664 Nuclear pore complex protein Nup214 OS=Homo sapiens OX=9606 GN=NUP214 PE=1 SV=2 5.72 1759.3 - 1.09E+07 - - - -1.3691 - 1.164 0.222 - 144.2 1 2 0 -0.0013 9 0 0 0 5.79E+08 2.73E+08 - - - 1.1196 0.7703 221125_WJC_METTL3_EV_vs_WT_F04.06603.06603.2 2.08 12-Jul A.VEDEGLK[136.11].G "sp|P0DMV8|HS71A_HUMAN,sp|P0DMV9|HS71B_HUMAN,tr|V9GZ37|V9GZ37_HUMAN,tr|A0A0G2JIW1|A0A0G2JIW1_HUMAN" 4 796.4058 0.48 42361 6603 2 796.403616 399.2102 Heat shock 70 kDa protein 1A OS=Homo sapiens OX=9606 GN=HSPA1A PE=1 SV=1 4.14 1759.4 - 4.70E+06 - - - -2.7411 - 1.507 0.241 - 145.4 1 1 0 -0.0022 7 0 0 0 8.54E+07 1.77E+08 - - - 2.1198 0.993 221125_WJC_METTL3_EV_vs_WT_F04.06604.06604.2 0.149 16-Jul R.IQAGDPVAR[166.11].Y "sp|P19388|RPAB1_HUMAN,tr|A0A0A0MQR7|A0A0A0MQR7_HUMAN,tr|A0A087WVZ9|A0A087WVZ9_HUMAN,tr|A0A087WWX0|A0A087WWX0_HUMAN" 4 935.5064 1.42 42362 6604 2 935.507753 468.7605 "DNA-directed RNA polymerases I, II, and III subunit RPABC1 OS=Homo sapiens OX=9606 GN=POLR2E PE=1 SV=4" 5.84 1759.5 - 1.39E+06 - - - 1.4463 - 1.561 0.122 - 116.2 1 2 0 0.0014 9 0 0 0 1.39E+08 9.76E+07 - - - 1.23 0.9944 221125_WJC_METTL3_EV_vs_WT_F04.06606.06606.2 0.738 16-Aug K.EVTEQLQAK.N sp|Q8TAV0|FA76A_HUMAN 1 1044.5451 0.69 42364 6606 2 1044.542416 523.2798 Protein FAM76A OS=Homo sapiens OX=9606 GN=FAM76A PE=2 SV=1 4.53 1759.8 - 467445 - - - -2.6069 - 1.552 0.237 - 142.8 2 2 0 -0.0027 9 0 0 0 6.01E+06 8.67E+06 - - - 1.9278 0.9977 221125_WJC_METTL3_EV_vs_WT_F04.06612.06612.2 0.0359 12-Jul R.SPFEDSR.G "sp|O14654|IRS4_HUMAN,tr|A0A804CF45|A0A804CF45_HUMAN" 2 836.3664 0.92 42366 6612 2 836.364647 419.1905 Insulin receptor substrate 4 OS=Homo sapiens OX=9606 GN=IRS4 PE=1 SV=1 4.37 1760.6 - 1.95E+06 - - - -2.1522 - 1.376 0.317 - 230.7 1 2 0 -0.0018 7 0 0 0 2.85E+08 3.09E+08 - - - 2.3931 0.9986 221125_WJC_METTL3_EV_vs_WT_F04.06615.06615.2 0.143 12-Jun R.SPFEDSR[166.11].G "sp|O14654|IRS4_HUMAN,tr|A0A804CF45|A0A804CF45_HUMAN" 2 846.3747 0.92 42367 6615 2 846.373183 424.1946 Insulin receptor substrate 4 OS=Homo sapiens OX=9606 GN=IRS4 PE=1 SV=1 4.37 1760.9 - 2.92E+06 - - - -1.8124 - 1.445 0.327 - 169.3 1 2 0 -0.0015 7 0 0 0 2.85E+08 3.09E+08 - - - 2.6221 0.978 221125_WJC_METTL3_EV_vs_WT_F04.06620.06620.2 0.975 16-Jul R.IQAGDPVAR.Y "sp|P19388|RPAB1_HUMAN,tr|A0A0A0MQR7|A0A0A0MQR7_HUMAN,tr|A0A087WVZ9|A0A087WVZ9_HUMAN,tr|A0A087WWX0|A0A087WWX0_HUMAN" 4 925.4981 0.92 42369 6620 2 925.49656 463.7563 "DNA-directed RNA polymerases I, II, and III subunit RPABC1 OS=Homo sapiens OX=9606 GN=POLR2E PE=1 SV=4" 5.84 1761.6 - 4.07E+06 - - - -1.6964 - 1.276 0.115 - 148.5 2 2 0 -0.0016 9 0 0 0 1.46E+08 1.58E+08 - - - 0.4606 0.9958 221125_WJC_METTL3_EV_vs_WT_F04.06621.06621.2 0.018 16-Aug R.FSTPEQAAK[136.11].N "sp|P14866|HNRPL_HUMAN,tr|M0QYT0|M0QYT0_HUMAN,tr|A0A3B3ITJ4|A0A3B3ITJ4_HUMAN,tr|M0QXS5|M0QXS5_HUMAN" 4 985.496 0.42 42370 6621 2 985.493284 493.7553 Heterogeneous nuclear ribonucleoprotein L OS=Homo sapiens OX=9606 GN=HNRNPL PE=1 SV=2 6 1761.7 - 2.16E+06 - - - -2.7671 - 1.409 0.303 - 148.1 1 2 0 -0.0027 9 0 0 0 7.32E+07 1.74E+08 - - - 2.2701 0.9844 221125_WJC_METTL3_EV_vs_WT_F04.06625.06625.2 4.18E-05 20-Nov R.LAGENMTGAAK.P "sp|O95831|AIFM1_HUMAN,tr|A0A6Q8PHJ9|A0A6Q8PHJ9_HUMAN,tr|A0A6Q8PFS4|A0A6Q8PFS4_HUMAN,tr|E9PMA0|E9PMA0_HUMAN,tr|A0A7I2PK44|A0A7I2PK44_HUMAN,tr|A0A6Q8PG15|A0A6Q8PG15_HUMAN,tr|A0A6Q8PFE1|A0A6Q8PFE1_HUMAN,tr|A0A6Q8PHJ4|A0A6Q8PHJ4_HUMAN,tr|A0A6Q8PFQ8|A0A6Q8PFQ8_HUMAN,tr|A0A6Q8PHC0|A0A6Q8PHC0_HUMAN,tr|A0A6Q8PFM5|A0A6Q8PFM5_HUMAN" 11 1061.5175 0.49 42372 6625 2 1061.515363 531.766 "Apoptosis-inducing factor 1, mitochondrial OS=Homo sapiens OX=9606 GN=AIFM1 PE=1 SV=1" 6 1762.1 - 336926 - - - -2.0546 - 2.276 0.493 - 275.7 1 1 0 -0.0022 11 0 0 0 1.04E+07 2.13E+07 - - - 4.9065 0.9993 221125_WJC_METTL3_EV_vs_WT_F04.06627.06627.2 0.0211 14-Aug R.MGANSLER[166.11].M "sp|P52272|HNRPM_HUMAN,sp|P52272|HNRPM_HUMAN,tr|M0R2I7|M0R2I7_HUMAN,tr|M0QY96|M0QY96_HUMAN,tr|A0A087X0X3|A0A087X0X3_HUMAN,tr|M0QZM1|M0QZM1_HUMAN,tr|M0QZM1|M0QZM1_HUMAN" 7 886.4206 1.57 42373 6627 2 886.418403 444.2176 Heterogeneous nuclear ribonucleoprotein M OS=Homo sapiens OX=9606 GN=HNRNPM PE=1 SV=3 5.75 1762.4 - 1.24E+06 - - - -2.5022 - 1.768 0.419 - 251.6 1 2 0 -0.0022 8 0 0 0 1.15E+08 7.35E+07 - - - 3.8537 0.9937 221125_WJC_METTL3_EV_vs_WT_F04.06629.06629.2 0.103 12-Aug R.IHGVGFK[136.11].K "sp|P62899|RL31_HUMAN,tr|B7Z4C8|B7Z4C8_HUMAN,tr|B7Z4E3|B7Z4E3_HUMAN,tr|B8ZZK4|B8ZZK4_HUMAN,tr|H7C2W9|H7C2W9_HUMAN,tr|C9JU56|C9JU56_HUMAN" 6 764.4425 0.08 42374 6629 2 764.440828 383.2285 60S ribosomal protein L31 OS=Homo sapiens OX=9606 GN=RPL31 PE=1 SV=1 8.76 1762.6 - 900808 - - - -2.1336 - 1.247 0.247 - 210 1 2 0 -0.0016 7 0 0 0 6.25E+06 7.58E+07 - - - 1.5643 0.9994 221125_WJC_METTL3_EV_vs_WT_F04.06635.06635.2 0.000237 22-Nov K.MIGQATAADQEK.N sp|Q13015|AF1Q_HUMAN 1 1261.5973 1.7 42375 6635 2 1261.593467 631.8059 Protein AF1q OS=Homo sapiens OX=9606 GN=MLLT11 PE=1 SV=1 4.37 1763.5 - 216805 - - - -2.9994 - 1.869 0.56 - 237.2 1 2 0 -0.0038 12 0 0 0 3.87E+07 2.27E+07 - - - 4.8215 0.9995 221125_WJC_METTL3_EV_vs_WT_F04.06637.06637.2 0.000886 14-Aug R.MGANSLER.M "sp|P52272|HNRPM_HUMAN,sp|P52272|HNRPM_HUMAN,tr|M0R2I7|M0R2I7_HUMAN,tr|M0QY96|M0QY96_HUMAN,tr|A0A087X0X3|A0A087X0X3_HUMAN,tr|M0QZM1|M0QZM1_HUMAN,tr|M0QZM1|M0QZM1_HUMAN" 7 876.4124 1.42 42376 6637 2 876.410816 439.2135 Heterogeneous nuclear ribonucleoprotein M OS=Homo sapiens OX=9606 GN=HNRNPM PE=1 SV=3 5.75 1763.7 - 3.02E+06 - - - -1.7515 - 1.867 0.389 - 240.2 1 2 0 -0.0015 8 0 0 0 1.17E+08 8.21E+07 - - - 3.7966 0.9996 221125_WJC_METTL3_EV_vs_WT_F04.06642.06642.2 0.00017 22-Oct K.MIGQATAADQEK[136.11].N sp|Q13015|AF1Q_HUMAN 1 1269.6115 1.7 42380 6642 2 1269.609765 635.813 Protein AF1q OS=Homo sapiens OX=9606 GN=MLLT11 PE=1 SV=1 4.37 1764.2 - 253592 - - - -1.328 - 1.792 0.436 - 198.6 1 2 0 -0.0017 12 0 0 0 3.87E+07 2.27E+07 - - - 3.7956 0.9993 221125_WJC_METTL3_EV_vs_WT_F04.06645.06645.2 0.0033 16-Aug R.TAQEVETYR.R "sp|P17844|DDX5_HUMAN,tr|J3QR02|J3QR02_HUMAN,tr|A0A7I2V507|A0A7I2V507_HUMAN,tr|J3KTA4|J3KTA4_HUMAN,tr|J3KTQ4|J3KTQ4_HUMAN,tr|A0A7I2V2S0|A0A7I2V2S0_HUMAN,tr|J3QRQ7|J3QRQ7_HUMAN" 7 1095.5197 1.71 42381 6645 2 1095.517644 548.7671 Probable ATP-dependent RNA helicase DDX5 OS=Homo sapiens OX=9606 GN=DDX5 PE=1 SV=1 4.53 1764.6 - 4.00E+06 - - - -1.8338 - 1.459 0.435 - 174.2 1 2 0 -0.002 9 0 0 0 1.38E+08 8.02E+07 - - - 3.3461 0.9994 221125_WJC_METTL3_EV_vs_WT_F04.06651.06651.2 0.00277 16-Aug R.VNGSLAVSR[166.11].A "sp|O75688|PPM1B_HUMAN,sp|P35813|PPM1A_HUMAN,tr|B8ZZF0|B8ZZF0_HUMAN,tr|A0A3B3IS24|A0A3B3IS24_HUMAN,tr|C9JIR6|C9JIR6_HUMAN" 5 911.5064 3.19 42384 6651 2 911.504186 456.7605 Protein phosphatase 1B OS=Homo sapiens OX=9606 GN=PPM1B PE=1 SV=1 9.72 1765.4 - 2.14E+07 - - - -2.4289 - 2.086 0.382 - 211.4 1 2 0 -0.0022 9 0 0 0 3.58E+09 1.12E+09 - - - 3.9889 0.9117 221125_WJC_METTL3_EV_vs_WT_F04.06656.06656.2 1.29 14-May R.LPSGNHMK[136.11].E sp|P43121|MUC18_HUMAN 1 890.4524 4.39 42387 6656 2 890.450876 446.2335 Cell surface glycoprotein MUC18 OS=Homo sapiens OX=9606 GN=MCAM PE=1 SV=2 8.76 1766.1 - 895334 - - - -1.68 - 1.15 0.056 - 67.1 6 2 0 -0.0015 8 0 0 0 2.92E+08 6.67E+07 - - - -0.4719 0.9999 221125_WJC_METTL3_EV_vs_WT_F04.06660.06660.2 1.74E-06 16-Dec R.TAQEVETYR[166.11].R "sp|P17844|DDX5_HUMAN,tr|J3QR02|J3QR02_HUMAN,tr|A0A7I2V507|A0A7I2V507_HUMAN,tr|J3KTA4|J3KTA4_HUMAN,tr|J3KTQ4|J3KTQ4_HUMAN,tr|A0A7I2V2S0|A0A7I2V2S0_HUMAN,tr|J3QRQ7|J3QRQ7_HUMAN" 7 1105.5279 3.84 42389 6660 2 1105.526409 553.7712 Probable ATP-dependent RNA helicase DDX5 OS=Homo sapiens OX=9606 GN=DDX5 PE=1 SV=1 4.53 1766.6 - 3.04E+06 - - - -1.3695 - 2.199 0.552 - 774.2 1 2 0 -0.0015 9 0 0 0 3.43E+08 8.94E+07 - - - 5.3973 0.9965 221125_WJC_METTL3_EV_vs_WT_F04.06662.06662.2 2.31 16-Aug R.NAVLNTEAR[166.11].T sp|Q969V3|NCLN_HUMAN 1 996.5228 2.91 42391 6662 2 996.522577 499.2687 Nicalin OS=Homo sapiens OX=9606 GN=NCLN PE=1 SV=2 6 1766.7 - 848630 - - - -0.2017 - 1.421 0.176 - 189.8 1 2 0 -0.0002 9 0 0 0 1.30E+08 4.46E+07 - - - 1.3574 0.9992 221125_WJC_METTL3_EV_vs_WT_F04.06668.06668.2 0.009 14-Aug K.AQC[160.03]PIVER[166.11].L "sp|P46782|RS5_HUMAN,tr|M0R0F0|M0R0F0_HUMAN,tr|M0R0R2|M0R0R2_HUMAN" 3 981.4941 0.97 42395 6668 2 981.496827 491.7543 40S ribosomal protein S5 OS=Homo sapiens OX=9606 GN=RPS5 PE=1 SV=4 6.04 1767.4 - 7.58E+06 - - - 2.757 - 1.771 0.445 - 398.6 1 2 0 0.0027 8 0 0 0 2.77E+09 2.86E+09 - - - 4.0507 0.9958 221125_WJC_METTL3_EV_vs_WT_F04.06672.06672.2 0.00125 18-Jul R.IYVSANSGAR[166.11].L "sp|Q13085|ACACA_HUMAN,tr|Q59FY4|Q59FY4_HUMAN" 2 1046.5384 0 42399 6672 2 1046.539577 524.2765 Acetyl-CoA carboxylase 1 OS=Homo sapiens OX=9606 GN=ACACA PE=1 SV=2 8.75 1767.8 - 326423 - - - 1.0979 - 1.396 0.203 - 158.4 1 2 0 0.0011 10 0 0 0 4.00E+06 1.12E+09 - - - 1.4712 0.9987 221125_WJC_METTL3_EV_vs_WT_F04.06680.06680.2 0.19 14-Jul R.GPGPLQER.S "sp|P43243|MATR3_HUMAN,tr|A8MXP9|A8MXP9_HUMAN,tr|D6R991|D6R991_HUMAN,tr|A0A0R4J2E8|A0A0R4J2E8_HUMAN,tr|H0Y8T4|H0Y8T4_HUMAN,tr|D6REM6|D6REM6_HUMAN" 6 852.4454 1.33 42403 6680 2 852.444619 427.23 Matrin-3 OS=Homo sapiens OX=9606 GN=MATR3 PE=1 SV=2 6 1768.8 - 6.53E+07 - - - -0.8763 - 1.53 0.26 - 207.8 1 2 0 -0.0007 8 0 0 0 4.95E+09 3.73E+09 - - - 2.2437 0.9997 221125_WJC_METTL3_EV_vs_WT_F04.06681.06681.2 0.0812 18-Oct R.VAEQAANDLR.A "sp|Q7Z406|MYH14_HUMAN,tr|A1L2Z2|A1L2Z2_HUMAN" 2 1085.5465 0.56 42404 6681 2 1085.545633 543.7805 Myosin-14 OS=Homo sapiens OX=9606 GN=MYH14 PE=1 SV=2 4.37 1768.9 - 1.43E+06 - - - -0.8318 - 1.949 0.384 - 505 1 2 0 -0.0009 10 0 0 0 2.96E+07 5.32E+07 - - - 3.7396 0.9997 221125_WJC_METTL3_EV_vs_WT_F04.06686.06686.2 0.0016 12-Aug R.YNGLIHR[166.11].K "sp|P46779|RL28_HUMAN,tr|H0YMF4|H0YMF4_HUMAN,tr|H0YLP6|H0YLP6_HUMAN,tr|H0YKD8|H0YKD8_HUMAN" 4 881.4747 1.38 42406 6686 2 881.474741 441.7446 60S ribosomal protein L28 OS=Homo sapiens OX=9606 GN=RPL28 PE=1 SV=3 8.75 1769.5 - 1.96E+06 - - - 0.0408 - 1.56 0.448 - 254.8 1 2 0 0 7 0 0 0 1.13E+08 8.13E+07 - - - 3.7589 0.965 221125_WJC_METTL3_EV_vs_WT_F04.06692.06692.2 0.00192 20-Aug K.K[136.11]GPGEVAGTVT.G "sp|Q86U44|MTA70_HUMAN,tr|F5H6D8|F5H6D8_HUMAN,tr|H0YFV6|H0YFV6_HUMAN,tr|B4DTN4|B4DTN4_HUMAN" 4 1022.5488 0.04 42410 6692 2 1022.54671 512.2817 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 6 1770.4 - 2.39E+06 - - - -2.0195 - 1.835 0.405 - 141.8 1 1 0 -0.0021 11 0 0 0 8.17E+06 1.83E+08 - - - 3.6739 0.798 221125_WJC_METTL3_EV_vs_WT_F04.06693.06693.2 0.32 12-Aug S.TLEPVEK[136.11].A "sp|P48741|HSP77_HUMAN,sp|P54652|HSP72_HUMAN,sp|P0DMV8|HS71A_HUMAN,sp|P34931|HS71L_HUMAN,sp|P0DMV9|HS71B_HUMAN,sp|P17066|HSP76_HUMAN,tr|Q53FA3|Q53FA3_HUMAN,tr|V9GZ37|V9GZ37_HUMAN,tr|A0A0G2JIW1|A0A0G2JIW1_HUMAN" 9 822.4578 0.06 42411 6693 2 822.45776 412.2362 Putative heat shock 70 kDa protein 7 OS=Homo sapiens OX=9606 GN=HSPA7 PE=5 SV=2 4.53 1770.5 - 1.44E+06 - - - -0.09 - 1.365 0.162 - 235.1 1 1 0 -0.0001 7 0 0 0 8.15E+06 1.30E+08 - - - 1.2234 0.9998 221125_WJC_METTL3_EV_vs_WT_F04.06705.06705.2 0.00208 14-Aug K.AQC[160.03]PIVER.L "sp|P46782|RS5_HUMAN,tr|M0R0F0|M0R0F0_HUMAN,tr|M0R0R2|M0R0R2_HUMAN" 3 971.4859 0.91 42417 6705 2 971.484531 486.7502 40S ribosomal protein S5 OS=Homo sapiens OX=9606 GN=RPS5 PE=1 SV=4 6.04 1771.9 - 2.60E+07 - - - -1.3587 - 1.819 0.544 - 380.6 1 2 0 -0.0013 8 0 0 0 2.77E+09 3.03E+09 - - - 4.863 0.9959 221125_WJC_METTL3_EV_vs_WT_F04.06706.06706.2 0.0592 12-Jun R.NEDVQLR[166.11].L "sp|P30153|2AAA_HUMAN,sp|P30154|2AAB_HUMAN,tr|E9PHZ6|E9PHZ6_HUMAN,tr|E9PPI5|E9PPI5_HUMAN" 4 882.4435 0.94 42418 6706 2 882.442264 442.229 Serine\threonine-protein phosphatase 2A 65 kDa regulatory subunit A alpha isoform OS=Homo sapiens OX=9606 GN=PPP2R1A PE=1 SV=4 4.37 1771.9 - 2.42E+06 - - - -1.361 - 1.54 0.149 - 198.4 1 2 0 -0.0012 7 0 0 0 2.72E+08 2.88E+08 - - - 1.5093 0.9976 221125_WJC_METTL3_EV_vs_WT_F04.06707.06707.2 0.0107 16-Sep R.VNGSLAVSR.A "sp|O75688|PPM1B_HUMAN,sp|P35813|PPM1A_HUMAN,tr|B8ZZF0|B8ZZF0_HUMAN,tr|A0A3B3IS24|A0A3B3IS24_HUMAN,tr|C9JIR6|C9JIR6_HUMAN" 5 901.4981 3.19 42419 6707 2 901.493953 451.7563 Protein phosphatase 1B OS=Homo sapiens OX=9606 GN=PPM1B PE=1 SV=1 9.72 1772 - 8.16E+07 - - - -4.6334 - 2.044 0.444 - 294.6 1 2 0 -0.0042 9 0 0 0 3.58E+09 1.12E+09 - - - 4.3873 0.9976 221125_WJC_METTL3_EV_vs_WT_F04.06708.06708.2 0.0278 14-Jun R.QQQLTAMK.V "sp|P35749|MYH11_HUMAN,sp|P35579|MYH9_HUMAN" 2 946.4906 1.23 42420 6708 2 946.488686 474.2526 Myosin-11 OS=Homo sapiens OX=9606 GN=MYH11 PE=1 SV=3 8.75 1772 - 2.16E+06 - - - -2.0233 - 1.401 0.302 - 186.1 1 2 0 -0.0019 8 0 0 0 8.43E+07 6.84E+07 - - - 2.2879 0.9988 221125_WJC_METTL3_EV_vs_WT_F04.06711.06711.2 0.00313 14-Aug K.FQQAIDSR.E sp|P31944|CASPE_HUMAN 1 963.4774 1.56 42421 6711 2 963.474973 482.746 Caspase-14 OS=Homo sapiens OX=9606 GN=CASP14 PE=1 SV=2 5.84 1772.4 - 8.52E+06 - - - -2.5128 - 1.625 0.375 - 243.9 1 2 0 -0.0024 8 0 0 0 6.06E+08 3.88E+08 - - - 3.2743 0.9752 221125_WJC_METTL3_EV_vs_WT_F04.06712.06712.2 0.678 12-Jul K.VFEHIGK.K sp|P04040|CATA_HUMAN 1 828.4494 11.55 42422 6712 2 828.447351 415.232 Catalase OS=Homo sapiens OX=9606 GN=CAT PE=1 SV=3 6.72 1772.5 - 2.42E+06 - - - -2.4588 - 1.161 0.166 - 142.8 1 2 0 -0.002 7 0 0 0 8.53E+07 7.38E+06 - - - 0.7394 0.9992 221125_WJC_METTL3_EV_vs_WT_F04.06716.06716.2 0.000214 20-Oct R.VVVVGDQSAGK[136.11].T "sp|O60313|OPA1_HUMAN,tr|A0A2R8YD53|A0A2R8YD53_HUMAN,tr|C9JMB8|C9JMB8_HUMAN,tr|A0A2R8YE54|A0A2R8YE54_HUMAN,tr|A0A2R8YDM2|A0A2R8YDM2_HUMAN,tr|E5KLJ9|E5KLJ9_HUMAN,tr|A0A2R8Y4Q3|A0A2R8Y4Q3_HUMAN,tr|A0A2R8Y3X5|A0A2R8Y3X5_HUMAN,tr|A0A2R8YGE5|A0A2R8YGE5_HUMAN,tr|A0A2R8Y4G4|A0A2R8Y4G4_HUMAN,tr|A0A2R8YE78|A0A2R8YE78_HUMAN" 11 1065.591 1.43 42423 6716 2 1065.588673 533.8028 "Dynamin-like 120 kDa protein, mitochondrial OS=Homo sapiens OX=9606 GN=OPA1 PE=1 SV=3" 5.81 1773 - 618611 - - - -2.1594 - 1.826 0.388 - 310.7 1 2 0 -0.0023 11 0 0 0 4.19E+07 2.93E+07 - - - 3.5349 0.9946 221125_WJC_METTL3_EV_vs_WT_F04.06719.06719.2 0.155 14-Aug R.K[136.11]VGLIAAR[166.11].R "sp|P62917|RL8_HUMAN,tr|E9PP36|E9PP36_HUMAN,tr|E9PKU4|E9PKU4_HUMAN" 3 844.5613 0.94 42425 6719 2 844.558522 423.2879 60S ribosomal protein L8 OS=Homo sapiens OX=9606 GN=RPL8 PE=1 SV=2 11 1773.4 - 2.09E+06 - - - -3.339 - 1.745 0.23 - 257 1 2 0 -0.0028 8 0 0 0 8.91E+07 9.51E+07 - - - 2.418 0.9966 221125_WJC_METTL3_EV_vs_WT_F04.06720.06720.2 0.126 18-Sep K.APQVVAEAAK[136.11].T sp|O60832|DKC1_HUMAN 1 990.5589 0.61 42426 6720 2 990.55539 496.2867 H\ACA ribonucleoprotein complex subunit DKC1 OS=Homo sapiens OX=9606 GN=DKC1 PE=1 SV=3 6.05 1773.4 - 2.70E+06 - - - -3.5889 - 1.814 0.316 - 272.1 1 2 0 -0.0036 10 0 0 0 7.71E+07 1.27E+08 - - - 3.0362 0.9998 221125_WJC_METTL3_EV_vs_WT_F04.06722.06722.2 1.94E-05 20-Oct R.VVVVGDQSAGK.T "sp|O60313|OPA1_HUMAN,tr|A0A2R8YD53|A0A2R8YD53_HUMAN,tr|C9JMB8|C9JMB8_HUMAN,tr|A0A2R8YE54|A0A2R8YE54_HUMAN,tr|A0A2R8YDM2|A0A2R8YDM2_HUMAN,tr|E5KLJ9|E5KLJ9_HUMAN,tr|A0A2R8Y4Q3|A0A2R8Y4Q3_HUMAN,tr|A0A2R8Y3X5|A0A2R8Y3X5_HUMAN,tr|A0A2R8YGE5|A0A2R8YGE5_HUMAN,tr|A0A2R8Y4G4|A0A2R8Y4G4_HUMAN,tr|A0A2R8YE78|A0A2R8YE78_HUMAN" 11 1057.5768 1.4 42428 6722 2 1057.576142 529.7957 "Dynamin-like 120 kDa protein, mitochondrial OS=Homo sapiens OX=9606 GN=OPA1 PE=1 SV=3" 5.81 1773.6 - 594361 - - - -0.5976 - 1.95 0.494 - 316.2 1 2 0 -0.0006 11 0 0 0 4.20E+07 3.01E+07 - - - 4.4961 0.9993 221125_WJC_METTL3_EV_vs_WT_F04.06727.06727.2 0.0125 16-Oct R.YLTAEETDK[136.11].L sp|Q9HCD5|NCOA5_HUMAN 1 1076.5117 2.09 42431 6727 2 1076.509061 539.2631 Nuclear receptor coactivator 5 OS=Homo sapiens OX=9606 GN=NCOA5 PE=1 SV=2 4.14 1774.2 - 959918 - - - -2.47 - 1.95 0.398 - 252.8 1 2 0 -0.0027 9 0 0 0 1.00E+08 4.80E+07 - - - 3.9119 0.9845 221125_WJC_METTL3_EV_vs_WT_F04.06728.06728.2 0.111 14-Jul R.STLEPVEK.A "sp|P48741|HSP77_HUMAN,sp|P0DMV8|HS71A_HUMAN,sp|P0DMV9|HS71B_HUMAN,sp|P17066|HSP76_HUMAN,tr|V9GZ37|V9GZ37_HUMAN,tr|A0A0G2JIW1|A0A0G2JIW1_HUMAN" 6 901.4757 0.1 42432 6728 2 901.472177 451.7451 Putative heat shock 70 kDa protein 7 OS=Homo sapiens OX=9606 GN=HSPA7 PE=5 SV=2 4.53 1774.2 - 8.10E+07 - - - -3.867 - 1.493 0.217 - 248.7 1 2 0 -0.0035 8 0 0 0 2.68E+09 2.63E+10 - - - 1.8514 0.9963 221125_WJC_METTL3_EV_vs_WT_F04.06736.06736.2 0.24 14-Aug R.GPGPLQER[166.11].S "sp|P43243|MATR3_HUMAN,tr|A8MXP9|A8MXP9_HUMAN,tr|D6R991|D6R991_HUMAN,tr|A0A0R4J2E8|A0A0R4J2E8_HUMAN,tr|H0Y8T4|H0Y8T4_HUMAN,tr|D6REM6|D6REM6_HUMAN" 6 862.4536 1.33 42435 6736 2 862.451854 432.2341 Matrin-3 OS=Homo sapiens OX=9606 GN=MATR3 PE=1 SV=2 6 1775.2 - 4.71E+07 - - - -2.0662 - 1.568 0.209 - 298.8 1 2 0 -0.0018 8 0 0 0 5.11E+09 3.84E+09 - - - 1.9407 0.9696 221125_WJC_METTL3_EV_vs_WT_F04.06741.06741.2 0.0642 14-Aug R.NMGYVQQR[166.11].R "sp|O43684|BUB3_HUMAN,tr|J3QT28|J3QT28_HUMAN" 2 1004.4737 0.14 42438 6741 2 1004.469197 503.2441 Mitotic checkpoint protein BUB3 OS=Homo sapiens OX=9606 GN=BUB3 PE=1 SV=1 8.75 1775.8 - 983769 - - - -4.5019 - 1.327 0.241 - 362.3 1 2 0 -0.0045 8 0 0 0 1.82E+07 1.33E+08 - - - 1.6729 0.9997 221125_WJC_METTL3_EV_vs_WT_F04.06751.06751.2 0.000393 13/20 K.GPGLAVQSGDK[136.11].T sp|Q96PK6|RBM14_HUMAN 1 1035.544 6.06 42443 6751 2 1035.541574 518.7793 RNA-binding protein 14 OS=Homo sapiens OX=9606 GN=RBM14 PE=1 SV=2 5.84 1776.9 - 2.48E+06 - - - -2.3659 - 2.36 0.495 - 799.4 1 2 0 -0.0024 11 0 0 0 9.04E+08 1.49E+08 - - - 5.0192 0.9994 221125_WJC_METTL3_EV_vs_WT_F04.06753.06753.2 0.00639 16-Aug R.YLTAEETDK.L sp|Q9HCD5|NCOA5_HUMAN 1 1068.4975 2.09 42444 6753 2 1068.49581 535.256 Nuclear receptor coactivator 5 OS=Homo sapiens OX=9606 GN=NCOA5 PE=1 SV=2 4.14 1777.2 - 2.96E+06 - - - -1.6004 - 1.745 0.371 - 176.7 1 2 0 -0.0017 9 0 0 0 1.00E+08 4.80E+07 - - - 3.3914 0.9914 221125_WJC_METTL3_EV_vs_WT_F04.06763.06763.2 0.0956 22-Jul K.LSPATPTSEGPK[136.11].V "sp|Q8N1G0|ZN687_HUMAN,tr|F8WCX2|F8WCX2_HUMAN" 2 1191.6227 0.78 42449 6763 2 1191.618966 596.8186 Zinc finger protein 687 OS=Homo sapiens OX=9606 GN=ZNF687 PE=1 SV=1 6 1778.4 - 310399 - - - -3.1067 - 1.429 0.258 - 135.8 1 2 0 -0.0037 12 0 0 0 8.40E+06 1.08E+07 - - - 1.8847 0.9956 221125_WJC_METTL3_EV_vs_WT_F04.06765.06765.2 0.245 12-Jun R.NEDVQLR.L "sp|P30153|2AAA_HUMAN,sp|P30154|2AAB_HUMAN,tr|E9PHZ6|E9PHZ6_HUMAN,tr|E9PPI5|E9PPI5_HUMAN" 4 872.4352 0.7 42450 6765 2 872.433835 437.2249 Serine\threonine-protein phosphatase 2A 65 kDa regulatory subunit A alpha isoform OS=Homo sapiens OX=9606 GN=PPP2R1A PE=1 SV=4 4.37 1778.6 - 6.76E+06 - - - -1.5589 - 1.488 0.168 - 323.2 1 2 0 -0.0014 7 0 0 0 3.03E+08 4.35E+08 - - - 1.5407 0.9994 221125_WJC_METTL3_EV_vs_WT_F04.06766.06766.2 0.00475 14-Jun R.GSNGAFYK.G "sp|P51114|FXR1_HUMAN,sp|P51116|FXR2_HUMAN,sp|Q06787|FMR1_HUMAN,tr|A0A087WWU4|A0A087WWU4_HUMAN,tr|E9PFF5|E9PFF5_HUMAN,tr|A0A087WY29|A0A087WY29_HUMAN,tr|R9WNI0|R9WNI0_HUMAN,tr|A8MQB8|A8MQB8_HUMAN,tr|C9JYQ6|C9JYQ6_HUMAN,tr|A0A087WXI3|A0A087WXI3_HUMAN,tr|A0A087X1M7|A0A087X1M7_HUMAN,tr|Q8IXW7|Q8IXW7_HUMAN,tr|G3V0J0|G3V0J0_HUMAN" 13 842.3923 1.75 42451 6766 2 842.391361 422.2034 Fragile X mental retardation syndrome-related protein 1 OS=Homo sapiens OX=9606 GN=FXR1 PE=1 SV=3 8.59 1778.7 - 2.94E+06 - - - -1.0755 - 1.384 0.417 - 210.3 1 2 0 -0.0009 8 0 0 0 5.02E+08 2.87E+08 - - - 3.1008 0.8372 221125_WJC_METTL3_EV_vs_WT_F04.06771.06771.2 0.948 16-May K.TYASFYEYK.C sp|Q9ULI1|NWD2_HUMAN 1 1170.5233 1487.96 42454 6771 2 1170.520207 586.2689 NACHT and WD repeat domain-containing protein 2 OS=Homo sapiens OX=9606 GN=NWD2 PE=2 SV=3 5.66 1779.3 - 542340 - - - -2.6774 - 0.809 0.15 - 82.9 1 2 0 -0.0031 9 0 0 0 1.18E+08 7.92E+04 - - - -0.4653 0.9988 221125_WJC_METTL3_EV_vs_WT_F04.06774.06774.2 0.0164 12-May R.YWC[160.03]NDGK.T "sp|P61626|LYSC_HUMAN,tr|A0A0B4J259|A0A0B4J259_HUMAN,tr|F8VV32|F8VV32_HUMAN" 3 941.3702 493.74 42455 6774 2 941.36822 471.6924 Lysozyme C OS=Homo sapiens OX=9606 GN=LYZ PE=1 SV=1 5.83 1779.7 - 1.22E+06 - - - -2.0523 - 1.05 0.505 - 86.8 1 2 0 -0.0019 7 0 0 0 2.30E+08 4.67E+05 - - - 2.9249 0.9976 221125_WJC_METTL3_EV_vs_WT_F04.06775.06775.2 0.131 16-Aug K.VGDVTPQVK[136.11].G "sp|Q13428|TCOF_HUMAN,tr|E7ETY2|E7ETY2_HUMAN,tr|H0Y8Y7|H0Y8Y7_HUMAN,tr|A0A6I8PRA0|A0A6I8PRA0_HUMAN" 4 949.5324 0.94 42456 6775 2 949.531451 475.7735 Treacle protein OS=Homo sapiens OX=9606 GN=TCOF1 PE=1 SV=3 5.81 1779.8 - 739448 - - - -0.9952 - 1.362 0.253 - 138.5 1 2 0 -0.0009 9 0 0 0 1.07E+08 1.14E+08 - - - 1.8032 0.9983 221125_WJC_METTL3_EV_vs_WT_F04.06783.06783.2 0.464 14-Jul K.QPSPEEIR.E "sp|Q9Y520|PRC2C_HUMAN,tr|A0A0A0MS30|A0A0A0MS30_HUMAN,tr|E7EPN9|E7EPN9_HUMAN" 3 954.4771 1.11 42460 6783 2 954.47503 478.2458 Protein PRRC2C OS=Homo sapiens OX=9606 GN=PRRC2C PE=1 SV=4 4.53 1781 - 2.21E+06 - - - -2.1268 - 1.581 0.304 - 148.8 1 2 0 -0.002 8 0 0 0 1.96E+08 1.77E+08 - - - 2.6672 0.9988 221125_WJC_METTL3_EV_vs_WT_F04.06787.06787.2 0.315 14-Jul R.STLEPVEK[136.11].A "sp|P48741|HSP77_HUMAN,sp|P0DMV8|HS71A_HUMAN,sp|P0DMV9|HS71B_HUMAN,sp|P17066|HSP76_HUMAN,tr|V9GZ37|V9GZ37_HUMAN,tr|A0A0G2JIW1|A0A0G2JIW1_HUMAN" 6 909.4899 0.1 42462 6787 2 909.488803 455.7522 Putative heat shock 70 kDa protein 7 OS=Homo sapiens OX=9606 GN=HSPA7 PE=5 SV=2 4.53 1781.4 - 6.09E+07 - - - -1.1655 - 1.584 0.272 - 249.5 1 2 0 -0.0011 8 0 0 0 2.69E+09 2.67E+10 - - - 2.4369 0.9975 221125_WJC_METTL3_EV_vs_WT_F04.06788.06788.2 0.00617 16-Aug R.VSGSELVQK.F "sp|P62195|PRS8_HUMAN,tr|J3QQM1|J3QQM1_HUMAN,tr|J3KRP2|J3KRP2_HUMAN,tr|J3QRR3|J3QRR3_HUMAN,tr|J3QSA9|J3QSA9_HUMAN,tr|J3QLH6|J3QLH6_HUMAN" 6 945.5131 1.8 42463 6788 2 945.511211 473.7638 26S proteasome regulatory subunit 8 OS=Homo sapiens OX=9606 GN=PSMC5 PE=1 SV=1 5.97 1781.5 - 956476 - - - -2.0095 - 1.877 0.189 - 139.6 1 2 0 -0.0019 9 0 0 0 1.66E+08 9.19E+07 - - - 2.258 0.9966 221125_WJC_METTL3_EV_vs_WT_F04.06801.06801.2 0.147 16-Jul R.VSGSELVQK[136.11].F "sp|P62195|PRS8_HUMAN,tr|J3QQM1|J3QQM1_HUMAN,tr|J3KRP2|J3KRP2_HUMAN,tr|J3QRR3|J3QRR3_HUMAN,tr|J3QSA9|J3QSA9_HUMAN,tr|J3QLH6|J3QLH6_HUMAN" 6 953.5273 1.78 42472 6801 2 953.525878 477.7709 26S proteasome regulatory subunit 8 OS=Homo sapiens OX=9606 GN=PSMC5 PE=1 SV=1 5.97 1783.1 - 2.56E+06 - - - -1.5028 - 1.415 0.245 - 102.9 2 2 0 -0.0014 9 0 0 0 1.62E+08 9.09E+07 - - - 1.7199 0.9998 221125_WJC_METTL3_EV_vs_WT_F04.06802.06802.2 0.000263 16-Sep R.VTDALNATR.A "sp|P10809|CH60_HUMAN,tr|A0A7I2V2X6|A0A7I2V2X6_HUMAN,tr|A0A7I2YQK6|A0A7I2YQK6_HUMAN,tr|A0A7I2V599|A0A7I2V599_HUMAN" 4 959.5036 1.28 42473 6802 2 959.503977 480.7591 "60 kDa heat shock protein, mitochondrial OS=Homo sapiens OX=9606 GN=HSPD1 PE=1 SV=2" 5.81 1783.1 - 1.53E+06 - - - 0.3835 - 2.043 0.435 - 321.7 1 2 0 0.0004 9 0 0 0 2.62E+07 2.04E+07 - - - 4.3206 0.9996 221125_WJC_METTL3_EV_vs_WT_F04.06816.06816.2 8.51E-05 18-Dec K.TPTQLEGATR.G sp|O94776|MTA2_HUMAN 1 1072.5513 0.11 42481 6816 2 1072.548465 537.2829 Metastasis-associated protein MTA2 OS=Homo sapiens OX=9606 GN=MTA2 PE=1 SV=1 5.66 1784.8 - 1.24E+06 - - - -2.6311 - 2.142 0.481 - 853.6 1 2 0 -0.0028 10 0 0 0 4.23E+07 3.73E+08 - - - 4.719 0.9987 221125_WJC_METTL3_EV_vs_WT_F04.06821.06821.2 0.044 22-Aug R.VLANPGNSQVAR[166.11].V "sp|Q14974|IMB1_HUMAN,tr|J3QR48|J3QR48_HUMAN" 2 1234.6658 1.32 42485 6821 2 1234.664978 618.3402 Importin subunit beta-1 OS=Homo sapiens OX=9606 GN=KPNB1 PE=1 SV=2 9.72 1785.4 - 188992 - - - -0.6285 - 1.39 0.305 - 72.7 1 2 0 -0.0008 12 0 0 0 4.53E+08 3.43E+08 - - - 2.1599 0.9956 221125_WJC_METTL3_EV_vs_WT_F04.06826.06826.2 0.407 14-Aug R.TGLEDPER.Y "sp|P35580|MYH10_HUMAN,tr|E7ERA5|E7ERA5_HUMAN" 2 915.4298 1.21 42488 6826 2 915.430343 458.7222 Myosin-10 OS=Homo sapiens OX=9606 GN=MYH10 PE=1 SV=3 4.14 1785.9 - 3.18E+06 - - - 0.6205 - 1.095 0.266 - 230.9 1 2 0 0.0006 8 0 0 0 2.67E+08 2.21E+08 - - - 1.2792 0.9997 221125_WJC_METTL3_EV_vs_WT_F04.06827.06827.2 0.00131 16-Oct K.NVATETQLK.G sp|Q5T3J3|LRIF1_HUMAN 1 1002.5346 1.78 42489 6827 2 1002.534701 502.2746 Ligand-dependent nuclear receptor-interacting factor 1 OS=Homo sapiens OX=9606 GN=LRIF1 PE=1 SV=1 6 1785.9 - 2.50E+06 - - - 0.1257 - 1.848 0.395 - 278 1 2 0 0.0001 9 0 0 0 7.24E+07 4.06E+07 - - - 3.7351 0.9986 221125_WJC_METTL3_EV_vs_WT_F04.06830.06830.2 0.144 14-Jun R.VAIEHLDK[136.11].L "sp|P48643|TCPE_HUMAN,tr|E9PCA1|E9PCA1_HUMAN,tr|B7ZAR1|B7ZAR1_HUMAN,tr|E7ENZ3|E7ENZ3_HUMAN" 4 931.5218 0.78 42491 6830 2 931.521273 466.7682 T-complex protein 1 subunit epsilon OS=Homo sapiens OX=9606 GN=CCT5 PE=1 SV=1 5.32 1786.3 - 1.59E+07 - - - -0.6001 - 1.425 0.272 - 102.5 1 2 0 -0.0006 8 0 0 0 3.44E+08 4.41E+08 - - - 2.118 0.9206 221125_WJC_METTL3_EV_vs_WT_F04.06834.06834.2 4.72 14-Apr K.VHPAVVIR[166.11].Q "sp|P62829|RL23_HUMAN,tr|J3QQT9|J3QQT9_HUMAN,tr|J3KT29|J3KT29_HUMAN,tr|J3KTJ3|J3KTJ3_HUMAN,tr|C9JD32|C9JD32_HUMAN" 5 899.558 1 42493 6834 2 899.557571 450.7863 60S ribosomal protein L23 OS=Homo sapiens OX=9606 GN=RPL23 PE=1 SV=1 9.73 1786.7 - 1.70E+06 - - - -0.5225 - 0.817 0.151 - 62.6 4 2 0 -0.0005 8 0 0 0 4.33E+08 4.35E+08 - - - -0.7224 0.8377 221125_WJC_METTL3_EV_vs_WT_F04.06835.06835.2 4.43 14-Apr K.VHPAVVIR.Q "sp|P62829|RL23_HUMAN,tr|J3QQT9|J3QQT9_HUMAN,tr|J3KT29|J3KT29_HUMAN,tr|J3KTJ3|J3KTJ3_HUMAN,tr|C9JD32|C9JD32_HUMAN" 5 889.5498 1 42494 6835 2 889.549097 445.7822 60S ribosomal protein L23 OS=Homo sapiens OX=9606 GN=RPL23 PE=1 SV=1 9.73 1786.8 - 1.69E+06 - - - -0.7577 - 0.902 0.03 - 76.6 2 2 0 -0.0007 8 0 0 0 4.33E+08 4.34E+08 - - - -1.1832 0.9963 221125_WJC_METTL3_EV_vs_WT_F04.06836.06836.2 0.321 12-Jun K.TYC[160.03]C[160.03]DLK.M sp|Q9Y6C9|MTCH2_HUMAN 1 958.3888 0.83 42495 6836 2 958.389475 480.2017 Mitochondrial carrier homolog 2 OS=Homo sapiens OX=9606 GN=MTCH2 PE=1 SV=1 5.5 1786.8 - 813319 - - - 0.6636 - 0.935 0.352 - 138.5 1 2 0 0.0006 7 0 0 0 1.83E+07 2.21E+07 - - - 1.4277 0.9995 221125_WJC_METTL3_EV_vs_WT_F04.06837.06837.2 0.00164 18-Oct K.IAEVDC[160.03]TAER.N sp|Q8NBS9|TXND5_HUMAN 1 1162.5288 0.42 42496 6837 2 1162.525982 582.2717 Thioredoxin domain-containing protein 5 OS=Homo sapiens OX=9606 GN=TXNDC5 PE=1 SV=2 4.14 1787 - 488819 - - - -2.4567 - 2.2 0.419 - 389.5 1 2 0 -0.0029 10 0 0 0 2.64E+07 6.25E+07 - - - 4.3357 0.9992 221125_WJC_METTL3_EV_vs_WT_F04.06840.06840.2 0.0372 16-Aug R.FSTPEQAAK.N "sp|P14866|HNRPL_HUMAN,tr|M0QYT0|M0QYT0_HUMAN,tr|A0A3B3ITJ4|A0A3B3ITJ4_HUMAN,tr|M0QXS5|M0QXS5_HUMAN" 4 977.4818 0.98 42497 6840 2 977.481202 489.7482 Heterogeneous nuclear ribonucleoprotein L OS=Homo sapiens OX=9606 GN=HNRNPL PE=1 SV=2 6 1787.4 - 3.58E+06 - - - -0.623 - 1.591 0.307 - 188.7 1 2 0 -0.0006 9 0 0 0 9.31E+08 9.46E+08 - - - 2.6517 0.9981 221125_WJC_METTL3_EV_vs_WT_F04.06841.06841.2 0.00334 22-Oct R.VLANPGNSQVAR.V "sp|Q14974|IMB1_HUMAN,tr|J3QR48|J3QR48_HUMAN" 2 1224.6575 1.32 42498 6841 2 1224.661953 613.336 Importin subunit beta-1 OS=Homo sapiens OX=9606 GN=KPNB1 PE=1 SV=2 9.72 1787.5 - 438206 - - - 3.6492 - 1.94 0.401 - 284.4 1 2 0 0.0045 12 0 0 0 4.53E+08 3.42E+08 - - - 3.745 0.9995 221125_WJC_METTL3_EV_vs_WT_F04.06842.06842.2 0.0479 14-Sep R.VAIEHLDK.L "sp|P48643|TCPE_HUMAN,tr|E9PCA1|E9PCA1_HUMAN,tr|B7ZAR1|B7ZAR1_HUMAN,tr|E7ENZ3|E7ENZ3_HUMAN" 4 923.5076 0.78 42499 6842 2 923.507253 462.7611 T-complex protein 1 subunit epsilon OS=Homo sapiens OX=9606 GN=CCT5 PE=1 SV=1 5.32 1787.5 - 1.03E+07 - - - -0.4104 - 1.819 0.289 - 275.9 1 2 0 -0.0004 8 0 0 0 3.42E+08 4.41E+08 - - - 2.9798 0.9996 221125_WJC_METTL3_EV_vs_WT_F04.06843.06843.2 0.0278 18-Dec K.IAEVDC[160.03]TAER[166.11].N sp|Q8NBS9|TXND5_HUMAN 1 1172.5371 0.45 42500 6843 2 1172.53571 587.2758 Thioredoxin domain-containing protein 5 OS=Homo sapiens OX=9606 GN=TXNDC5 PE=1 SV=2 4.14 1787.6 - 1.58E+06 - - - -1.1923 - 1.981 0.359 - 717.2 1 2 0 -0.0014 10 0 0 0 2.84E+07 6.37E+07 - - - 3.6003 0.9998 221125_WJC_METTL3_EV_vs_WT_F04.06844.06844.2 0.000651 20-Aug R.LEQGGTADGLR.E sp|O43290|SNUT1_HUMAN 1 1115.5571 2.29 42501 6844 2 1115.556945 558.7858 U4\U6.U5 tri-snRNP-associated protein 1 OS=Homo sapiens OX=9606 GN=SART1 PE=1 SV=1 4.37 1787.8 - 329687 - - - -0.1398 - 1.92 0.433 - 208.2 1 2 0 -0.0002 11 0 0 0 1.32E+08 5.76E+07 - - - 4.0038 0.9842 221125_WJC_METTL3_EV_vs_WT_F04.06847.06847.2 0.163 14-Sep R.GRLDSELR.N "sp|P48668|K2C6C_HUMAN,sp|P04259|K2C6B_HUMAN,sp|P13647|K2C5_HUMAN,sp|Q5XKE5|K2C79_HUMAN,sp|P02538|K2C6A_HUMAN,tr|F8W0C6|F8W0C6_HUMAN" 6 944.5039 53.72 42502 6847 2 944.502436 473.2592 "Keratin, type II cytoskeletal 6C OS=Homo sapiens OX=9606 GN=KRT6C PE=1 SV=3" 6.07 1788.1 - 4.65E+06 - - - -1.5955 - 2.008 0.183 - 278.4 1 2 1 -0.0015 8 0 0 0 2.19E+08 4.08E+06 - - - 2.4947 0.8709 221125_WJC_METTL3_EV_vs_WT_F04.06849.06849.2 0.524 20-Aug R.AAVTGQDEAIR[166.11].F sp|Q6P6B7|ANR16_HUMAN 1 1139.581 2.07 42503 6849 2 1139.574175 570.7978 Ankyrin repeat domain-containing protein 16 OS=Homo sapiens OX=9606 GN=ANKRD16 PE=1 SV=1 4.37 1788.4 - 141140 - - - -6.0075 - 1.321 0.205 - 76.9 1 2 0 -0.0068 11 0 0 0 3.23E+06 1.56E+06 - - - 1.3061 0.7999 221125_WJC_METTL3_EV_vs_WT_F04.06851.06851.2 0.926 14-Jul K.MIIEEAK[136.11]R[166.11].S "sp|P48643|TCPE_HUMAN,sp|P07942|LAMB1_HUMAN,tr|E9PCA1|E9PCA1_HUMAN,tr|A0A7I2V4J9|A0A7I2V4J9_HUMAN,tr|B7ZAR1|B7ZAR1_HUMAN,tr|G3XAI2|G3XAI2_HUMAN,tr|E7ENZ3|E7ENZ3_HUMAN,tr|A0A7I2V5X5|A0A7I2V5X5_HUMAN" 8 1006.56 0.52 42504 6851 2 1006.566121 504.2873 T-complex protein 1 subunit epsilon OS=Homo sapiens OX=9606 GN=CCT5 PE=1 SV=1 5.9 1788.6 - 3.65E+06 - - - 6.0593 - 1.252 0.168 - 172.8 1 2 0 0.0061 8 0 0 0 1.57E+08 3.01E+08 - - - 0.9577 0.9996 221125_WJC_METTL3_EV_vs_WT_F04.06852.06852.2 0.0684 14-Aug R.MEESFSSK[136.11].Y "sp|P42167|LAP2B_HUMAN,tr|G5E972|G5E972_HUMAN,tr|H0YJH7|H0YJH7_HUMAN" 3 951.4099 0.99 42505 6852 2 951.409405 476.7122 "Lamina-associated polypeptide 2, isoforms beta\gamma OS=Homo sapiens OX=9606 GN=TMPO PE=1 SV=2" 4.53 1788.6 - 2.19E+06 - - - -0.5182 - 1.702 0.35 - 185.8 1 2 0 -0.0005 8 0 0 0 8.77E+07 8.83E+07 - - - 3.2298 0.9993 221125_WJC_METTL3_EV_vs_WT_F04.06862.06862.2 0.0136 14-Jul K.DVPNSQLR[166.11].H sp|Q9Y5A9|YTHD2_HUMAN 1 937.4857 1.41 42510 6862 2 937.485321 469.7501 YTH domain-containing family protein 2 OS=Homo sapiens OX=9606 GN=YTHDF2 PE=1 SV=2 5.84 1789.8 - 7.65E+06 - - - -0.3659 - 1.209 0.415 - 202.1 1 2 0 -0.0003 8 0 0 0 1.29E+09 9.13E+08 - - - 2.6785 0.9996 221125_WJC_METTL3_EV_vs_WT_F04.06867.06867.2 0.00061 14-Jul K.DGTGWASK.Q "sp|P48634|PRC2A_HUMAN,sp|Q9Y520|PRC2C_HUMAN,tr|E7EPN9|E7EPN9_HUMAN" 3 820.3715 1.1 42513 6867 2 820.37138 411.193 Protein PRRC2A OS=Homo sapiens OX=9606 GN=PRRC2A PE=1 SV=3 5.84 1790.3 - 3.02E+06 - - - -0.1853 - 1.665 0.37 - 360.2 1 2 0 -0.0002 8 0 0 0 1.06E+08 9.62E+07 - - - 3.3114 0.9788 221125_WJC_METTL3_EV_vs_WT_F04.06868.06868.2 1.68 14-Jul R.SLDIDTAK[136.11].S "sp|Q9BTE7|DCNL5_HUMAN,tr|H0YCN4|H0YCN4_HUMAN,tr|E9PM04|E9PM04_HUMAN" 3 869.4586 4.73 42514 6868 2 869.459305 435.7366 DCN1-like protein 5 OS=Homo sapiens OX=9606 GN=DCUN1D5 PE=1 SV=1 4.21 1790.3 - 2.99E+06 - - - 0.8534 - 1.352 0.06 - 178.6 2 2 0 0.0007 8 0 0 0 1.21E+09 2.55E+08 - - - 0.259 0.9993 221125_WJC_METTL3_EV_vs_WT_F04.06869.06869.2 0.0127 20-Sep R.YISAAPGAEAK[136.11].Y "sp|Q8TB72|PUM2_HUMAN,sp|Q14671|PUM1_HUMAN,tr|Q5T1Z8|Q5T1Z8_HUMAN,tr|H0YDK8|H0YDK8_HUMAN,tr|A0A0C4DG68|A0A0C4DG68_HUMAN,tr|H0YEH2|H0YEH2_HUMAN,tr|Q5T1Z4|Q5T1Z4_HUMAN,tr|E9PR38|E9PR38_HUMAN" 8 1084.5644 1.93 42515 6869 2 1084.563709 543.2895 Pumilio homolog 2 OS=Homo sapiens OX=9606 GN=PUM2 PE=1 SV=2 6 1790.4 - 1.46E+06 - - - -0.6602 - 1.624 0.325 - 173.4 1 2 0 -0.0007 11 0 0 0 1.56E+09 8.10E+08 - - - 2.753 0.9736 221125_WJC_METTL3_EV_vs_WT_F04.06871.06871.2 0.0566 16-Jul R.VYDPASPQR.R "sp|Q6RFH5|WDR74_HUMAN,tr|E9PS41|E9PS41_HUMAN" 2 1031.5036 1.49 42517 6871 2 1031.499269 516.7591 WD repeat-containing protein 74 OS=Homo sapiens OX=9606 GN=WDR74 PE=1 SV=1 5.81 1790.6 - 414604 - - - -4.2075 - 1.291 0.249 - 149.9 1 2 0 -0.0043 9 0 0 0 2.44E+07 1.64E+07 - - - 1.6177 0.9996 221125_WJC_METTL3_EV_vs_WT_F04.06874.06874.2 0.0301 16-Sep R.SSSPVGLAK.W "sp|Q9NRA8|4ET_HUMAN,tr|B1AKL4|B1AKL4_HUMAN" 2 844.4654 0.98 42518 6874 2 844.464451 423.24 Eukaryotic translation initiation factor 4E transporter OS=Homo sapiens OX=9606 GN=EIF4ENIF1 PE=1 SV=2 8.47 1791 - 2.99E+06 - - - -1.1617 - 1.847 0.354 - 288.1 1 2 0 -0.001 9 0 0 0 8.30E+07 8.47E+07 - - - 3.4304 0.9972 221125_WJC_METTL3_EV_vs_WT_F04.06875.06875.2 0.0176 14-May K.ILQNYDNK[136.11].Q "sp|P0DJD0|RGPD1_HUMAN,sp|Q7Z3J3|RGPD4_HUMAN,sp|O14715|RGPD8_HUMAN,sp|P49792|RBP2_HUMAN,sp|P0DJD1|RGPD2_HUMAN,sp|A6NKT7|RGPD3_HUMAN,sp|Q99666|RGPD5_HUMAN,tr|A0A286YES2|A0A286YES2_HUMAN,tr|F8VYC4|F8VYC4_HUMAN,tr|J3KNE0|J3KNE0_HUMAN,tr|A0A1W2PNU4|A0A1W2PNU4_HUMAN,tr|J3KQ37|J3KQ37_HUMAN" 12 1014.5226 0.7 42519 6875 2 1014.522368 508.2686 RANBP2-like and GRIP domain-containing protein 1 OS=Homo sapiens OX=9606 GN=RGPD1 PE=2 SV=1 5.83 1791.1 - 900778 - - - -0.1893 - 1.231 0.269 - 51.9 2 2 0 -0.0002 8 0 0 0 3.89E+07 5.56E+07 - - - 1.5201 0.9985 221125_WJC_METTL3_EV_vs_WT_F04.06876.06876.2 0.585 16-Jul K.LEAQETLNK[136.11].G "sp|O00461|GOLI4_HUMAN,tr|F8W785|F8W785_HUMAN" 2 1052.5593 0.03 42520 6876 2 1052.558328 527.2869 Golgi integral membrane protein 4 OS=Homo sapiens OX=9606 GN=GOLIM4 PE=1 SV=1 4.53 1791.2 - 2.07E+06 - - - -0.9605 - 1.738 0.207 - 129.9 1 2 0 -0.001 9 0 0 0 1.90E+08 5.79E+09 - - - 2.1687 0.999 221125_WJC_METTL3_EV_vs_WT_F04.06881.06881.2 0.65 14-Jul K.DVPNSQLR.H sp|Q9Y5A9|YTHD2_HUMAN 1 927.4774 1.54 42524 6881 2 927.477216 464.746 YTH domain-containing family protein 2 OS=Homo sapiens OX=9606 GN=YTHDF2 PE=1 SV=2 5.84 1791.8 - 9.98E+06 - - - -0.1919 - 1.403 0.315 - 201.8 1 2 0 -0.0002 8 0 0 0 6.12E+08 3.98E+08 - - - 2.3888 0.9991 221125_WJC_METTL3_EV_vs_WT_F04.06883.06883.2 0.0986 16-Oct K.LEAQETLNK.G "sp|O00461|GOLI4_HUMAN,tr|F8W785|F8W785_HUMAN" 2 1044.5451 0.04 42525 6883 2 1044.545508 523.2798 Golgi integral membrane protein 4 OS=Homo sapiens OX=9606 GN=GOLIM4 PE=1 SV=1 4.53 1792 - 3.72E+06 - - - 0.3533 - 1.937 0.215 - 331.3 1 2 0 0.0004 9 0 0 0 1.91E+08 4.70E+09 - - - 2.5416 0.9999 221125_WJC_METTL3_EV_vs_WT_F04.06884.06884.2 0.00118 20-Dec K.AAAAAAALQAK[136.11].S "sp|P36578|RL4_HUMAN,tr|H3BM89|H3BM89_HUMAN,tr|H3BU31|H3BU31_HUMAN" 3 963.5593 1 42526 6884 2 963.559393 482.7869 60S ribosomal protein L4 OS=Homo sapiens OX=9606 GN=RPL4 PE=1 SV=5 8.8 1792 - 2.48E+06 - - - 0.1173 - 2.639 0.489 - 550.3 1 2 0 0.0001 11 0 0 0 1.27E+08 1.26E+08 - - - 5.2779 0.9999 221125_WJC_METTL3_EV_vs_WT_F04.06887.06887.2 0.000513 20-Dec K.AAAAAAALQAK.S "sp|P36578|RL4_HUMAN,tr|H3BM89|H3BM89_HUMAN,tr|H3BU31|H3BU31_HUMAN" 3 955.5451 1 42527 6887 2 955.54493 478.7798 60S ribosomal protein L4 OS=Homo sapiens OX=9606 GN=RPL4 PE=1 SV=5 8.8 1792.4 - 3.25E+06 - - - -0.157 - 2.586 0.482 - 570.3 1 2 0 -0.0001 11 0 0 0 1.27E+08 1.26E+08 - - - 5.1713 0.9906 221125_WJC_METTL3_EV_vs_WT_F04.06894.06894.2 1.5 14-Jun K.DVGSLDEK[136.11].M sp|Q99584|S10AD_HUMAN 1 869.4222 1.72 42532 6894 2 869.422177 435.7184 Protein S100-A13 OS=Homo sapiens OX=9606 GN=S100A13 PE=1 SV=1 4.03 1793.1 - 3.66E+06 - - - 0 - 1.208 0.16 - 90.1 2 2 0 0 8 0 0 0 4.04E+08 2.35E+08 - - - 0.6582 0.8417 221125_WJC_METTL3_EV_vs_WT_F04.06900.06900.2 12.4 12-May R.K[136.11]IGELVR[166.11].Y "sp|P55265|DSRAD_HUMAN,tr|A0A3B3IRQ9|A0A3B3IRQ9_HUMAN,tr|A0A3B3ISU1|A0A3B3ISU1_HUMAN,tr|A0A7P0Z4K3|A0A7P0Z4K3_HUMAN,tr|A0A3B3ISX1|A0A3B3ISX1_HUMAN,tr|A0A7P0Z4F9|A0A7P0Z4F9_HUMAN" 6 831.5297 0.77 42536 6900 2 831.529045 416.7721 Double-stranded RNA-specific adenosine deaminase OS=Homo sapiens OX=9606 GN=ADAR PE=1 SV=4 8.75 1793.8 - 4.93E+06 - - - -0.7973 - 1.018 0.002 - 99.3 4 2 0 -0.0007 7 0 0 0 9.99E+07 1.29E+08 - - - -1.1569 0.9936 221125_WJC_METTL3_EV_vs_WT_F04.06902.06902.2 2.84 12-Jun K.ANINIEK.A sp|P61026|RAB10_HUMAN 1 800.4392 2.27 42538 6902 2 800.438785 401.2269 Ras-related protein Rab-10 OS=Homo sapiens OX=9606 GN=RAB10 PE=1 SV=1 6.05 1793.9 - 3.23E+06 - - - -0.541 - 1.239 0.166 - 116 1 2 0 -0.0004 7 0 0 0 1.71E+08 7.54E+07 - - - 0.946 0.9998 221125_WJC_METTL3_EV_vs_WT_F04.06905.06905.2 0.0137 16-Oct R.VTDALNATR[166.11].A "sp|P10809|CH60_HUMAN,tr|A0A7I2V2X6|A0A7I2V2X6_HUMAN,tr|A0A7I2YQK6|A0A7I2YQK6_HUMAN,tr|A0A7I2V599|A0A7I2V599_HUMAN" 4 969.5119 1.28 42539 6905 2 969.511232 485.7632 "60 kDa heat shock protein, mitochondrial OS=Homo sapiens OX=9606 GN=HSPD1 PE=1 SV=2" 5.81 1794.3 - 1.34E+06 - - - -0.6673 - 2.133 0.396 - 334.9 1 2 0 -0.0006 9 0 0 0 3.40E+10 2.65E+10 - - - 4.1572 0.9752 221125_WJC_METTL3_EV_vs_WT_F04.06911.06911.2 0.807 14-Jul K.SIQSGPLK[136.11].L "sp|Q16891|MIC60_HUMAN,tr|B9A067|B9A067_HUMAN,tr|A0A087WYS0|A0A087WYS0_HUMAN,tr|D6RAW4|D6RAW4_HUMAN,tr|C9J406|C9J406_HUMAN" 5 836.4847 1.13 42541 6911 2 836.483481 419.2496 MICOS complex subunit MIC60 OS=Homo sapiens OX=9606 GN=IMMT PE=1 SV=1 8.47 1795.1 - 2.32E+06 - - - -1.4788 - 1.257 0.076 - 119.1 1 2 0 -0.0012 8 0 0 0 3.75E+08 3.33E+08 - - - 0.2918 0.9988 221125_WJC_METTL3_EV_vs_WT_F04.06913.06913.2 0.202 14-Jul R.MEESFSSK.Y "sp|P42167|LAP2B_HUMAN,tr|G5E972|G5E972_HUMAN,tr|H0YJH7|H0YJH7_HUMAN" 3 943.3957 0.98 42542 6913 2 943.395867 472.7051 "Lamina-associated polypeptide 2, isoforms beta\gamma OS=Homo sapiens OX=9606 GN=TMPO PE=1 SV=2" 4.53 1795.4 - 1.32E+06 - - - 0.1791 - 1.255 0.334 - 156.1 1 2 0 0.0002 8 0 0 0 8.80E+07 9.01E+07 - - - 2.1929 0.9962 221125_WJC_METTL3_EV_vs_WT_F04.06921.06921.2 0.228 14-Jun K.SIQSGPLK.L "sp|Q16891|MIC60_HUMAN,tr|B9A067|B9A067_HUMAN,tr|A0A087WYS0|A0A087WYS0_HUMAN,tr|D6RAW4|D6RAW4_HUMAN,tr|C9J406|C9J406_HUMAN" 5 828.4705 1.14 42545 6921 2 828.469888 415.2425 MICOS complex subunit MIC60 OS=Homo sapiens OX=9606 GN=IMMT PE=1 SV=1 8.47 1796.4 - 4.41E+06 - - - -0.7604 - 1.282 0.214 - 91.9 1 2 0 -0.0006 8 0 0 0 3.73E+08 3.28E+08 - - - 1.3706 0.9705 221125_WJC_METTL3_EV_vs_WT_F04.06925.06925.2 2.39 14-Jun K.DVGSLDEK.M sp|Q99584|S10AD_HUMAN 1 861.408 1.72 42546 6925 2 861.40712 431.7113 Protein S100-A13 OS=Homo sapiens OX=9606 GN=S100A13 PE=1 SV=1 4.03 1797 - 1.48E+07 - - - -0.9949 - 1.016 0.144 - 88.8 2 2 0 -0.0009 8 0 0 0 4.05E+08 2.35E+08 - - - 0.0177 0.9998 221125_WJC_METTL3_EV_vs_WT_F04.06926.06926.2 0.000791 20-Sep R.MGAGLGHGMDR[166.11].V "sp|P52272|HNRPM_HUMAN,tr|A0A087X0X3|A0A087X0X3_HUMAN,tr|M0QZM1|M0QZM1_HUMAN,tr|M0R2T0|M0R2T0_HUMAN" 4 1110.4938 1.5 42547 6926 2 1110.494761 556.2542 Heterogeneous nuclear ribonucleoprotein M OS=Homo sapiens OX=9606 GN=HNRNPM PE=1 SV=3 6.5 1797.1 - 409438 - - - 0.8627 - 2.151 0.499 - 327.8 1 2 0 0.001 11 0 0 0 5.83E+07 3.89E+07 - - - 4.7983 0.9997 221125_WJC_METTL3_EV_vs_WT_F04.06927.06927.2 0.103 20-Nov R.MGAGLGHGMDR.V "sp|P52272|HNRPM_HUMAN,tr|A0A087X0X3|A0A087X0X3_HUMAN,tr|M0QZM1|M0QZM1_HUMAN,tr|M0R2T0|M0R2T0_HUMAN" 4 1100.4855 1.53 42548 6927 2 1100.484022 551.25 Heterogeneous nuclear ribonucleoprotein M OS=Homo sapiens OX=9606 GN=HNRNPM PE=1 SV=3 6.5 1797.2 - 469976 - - - -1.373 - 2.181 0.39 - 485.6 1 2 0 -0.0015 11 0 0 0 5.93E+07 3.89E+07 - - - 4.0306 0.9985 221125_WJC_METTL3_EV_vs_WT_F04.06930.06930.2 0.00879 18-Sep R.AVLGANDPEK.N "sp|Q15738|NSDHL_HUMAN,tr|C9JDR0|C9JDR0_HUMAN" 2 1012.5189 2.06 42549 6930 2 1012.516136 507.2667 "Sterol-4-alpha-carboxylate 3-dehydrogenase, decarboxylating OS=Homo sapiens OX=9606 GN=NSDHL PE=1 SV=2" 4.37 1797.6 - 1.41E+06 - - - -2.7545 - 1.564 0.404 - 254.3 1 2 0 -0.0028 10 0 0 0 8.77E+07 4.27E+07 - - - 3.2725 0.9719 221125_WJC_METTL3_EV_vs_WT_F04.06932.06932.2 0.183 16-Sep K.AADIDQEVK.E sp|Q86VP6|CAND1_HUMAN 1 987.4873 0.74 42551 6932 2 987.480505 494.7509 Cullin-associated NEDD8-dissociated protein 1 OS=Homo sapiens OX=9606 GN=CAND1 PE=1 SV=2 4.03 1797.8 - 1.08E+06 - - - -6.871 - 1.898 0.315 - 329.9 1 2 0 -0.0068 9 0 0 0 3.86E+07 5.21E+07 - - - 3.2193 0.9994 221125_WJC_METTL3_EV_vs_WT_F04.06937.06937.2 0.146 18-Oct R.AEEIVAAQEK[136.11].S "sp|Q9Y4A5|TRRAP_HUMAN,tr|H0Y4W2|H0Y4W2_HUMAN,tr|F2Z2U4|F2Z2U4_HUMAN" 3 1094.5699 14.1 42554 6937 2 1094.568349 548.2922 Transformation\transcription domain-associated protein OS=Homo sapiens OX=9606 GN=TRRAP PE=1 SV=3 4.25 1798.4 - 721004 - - - -1.4206 - 2.134 0.276 - 403.2 1 2 0 -0.0016 10 0 0 0 2.05E+08 1.46E+07 - - - 3.1949 0.9995 221125_WJC_METTL3_EV_vs_WT_F04.06939.06939.2 0.00467 16-Oct K.AADIDQEVK[136.11].E sp|Q86VP6|CAND1_HUMAN 1 995.5015 0.71 42556 6939 2 995.499755 498.758 Cullin-associated NEDD8-dissociated protein 1 OS=Homo sapiens OX=9606 GN=CAND1 PE=1 SV=2 4.03 1798.6 - 1.82E+06 - - - -1.7428 - 1.825 0.393 - 437.9 1 2 0 -0.0017 9 0 0 0 3.91E+07 5.50E+07 - - - 3.6836 0.9443 221125_WJC_METTL3_EV_vs_WT_F04.06940.06940.2 0.000351 18-Sep M.GAGLGHGMDR[166.11].V "sp|P52272|HNRPM_HUMAN,tr|A0A087X0X3|A0A087X0X3_HUMAN,tr|M0QZM1|M0QZM1_HUMAN,tr|M0R2T0|M0R2T0_HUMAN" 4 979.4533 0.04 42557 6940 2 979.452179 490.7339 Heterogeneous nuclear ribonucleoprotein M OS=Homo sapiens OX=9606 GN=HNRNPM PE=1 SV=3 6.74 1798.7 - 1.08E+06 - - - -1.1629 - 1.632 0.299 - 203.3 1 1 0 -0.0011 10 0 0 0 1.47E+06 3.48E+07 - - - 2.6163 0.998 221125_WJC_METTL3_EV_vs_WT_F04.06944.06944.2 0.316 14-Jul R.GPGPLQER.S "sp|P43243|MATR3_HUMAN,tr|A8MXP9|A8MXP9_HUMAN,tr|D6R991|D6R991_HUMAN,tr|A0A0R4J2E8|A0A0R4J2E8_HUMAN,tr|H0Y8T4|H0Y8T4_HUMAN,tr|D6REM6|D6REM6_HUMAN" 6 852.4454 1.56 42560 6944 2 852.444444 427.23 Matrin-3 OS=Homo sapiens OX=9606 GN=MATR3 PE=1 SV=2 6 1799.1 - 2.44E+07 - - - -1.0816 - 1.393 0.26 - 194 1 2 0 -0.0009 8 0 0 0 1.41E+09 9.00E+08 - - - 1.9607 0.9013 221125_WJC_METTL3_EV_vs_WT_F04.06946.06946.2 0.0803 16-Aug E.SAALHAGLR[166.11].K "sp|O75410|TACC1_HUMAN,tr|E7EVI4|E7EVI4_HUMAN,tr|B4E3H6|B4E3H6_HUMAN,tr|H0YAY0|H0YAY0_HUMAN,tr|H0YBT8|H0YBT8_HUMAN,tr|E7ET87|E7ET87_HUMAN" 6 904.5118 3.17 42561 6946 2 904.512131 453.2632 Transforming acidic coiled-coil-containing protein 1 OS=Homo sapiens OX=9606 GN=TACC1 PE=1 SV=2 9.49 1799.3 - 492254 - - - 0.3449 - 1.389 0.259 - 217 1 1 0 0.0003 9 0 0 0 4.10E+07 1.29E+07 - - - 1.9045 0.9979 221125_WJC_METTL3_EV_vs_WT_F04.06947.06947.2 0.0892 14-Jun K.NYYQDTPK.Q sp|Q9Y3C1|NOP16_HUMAN 1 1027.4611 3.8 42562 6947 2 1027.460141 514.7378 Nucleolar protein 16 OS=Homo sapiens OX=9606 GN=NOP16 PE=1 SV=2 5.83 1799.5 - 301572 - - - -0.909 - 1.183 0.316 - 85.2 1 2 0 -0.0009 8 0 0 0 3.47E+07 9.13E+06 - - - 1.8815 0.9867 221125_WJC_METTL3_EV_vs_WT_F04.06949.06949.2 0.528 18-Jul R.LGSDLTSAQK[136.11].E sp|Q08378|GOGA3_HUMAN 1 1026.5437 10.54 42564 6949 2 1026.543879 514.2791 Golgin subfamily A member 3 OS=Homo sapiens OX=9606 GN=GOLGA3 PE=1 SV=2 5.84 1799.7 - 301572 - - - 0.1851 - 1.33 0.1 - 83.1 2 2 0 0.0002 10 0 0 0 4.02E+07 3.82E+06 - - - 0.4411 0.9986 221125_WJC_METTL3_EV_vs_WT_F04.06954.06954.2 1.74E-05 20-Dec K.AESAALHAGLR[166.11].K "sp|O75410|TACC1_HUMAN,tr|E7EVI4|E7EVI4_HUMAN,tr|B4E3H6|B4E3H6_HUMAN,tr|H0YAY0|H0YAY0_HUMAN,tr|H0YBT8|H0YBT8_HUMAN,tr|E7ET87|E7ET87_HUMAN" 6 1104.5915 1.4 42566 6954 2 1104.587448 553.303 Transforming acidic coiled-coil-containing protein 1 OS=Homo sapiens OX=9606 GN=TACC1 PE=1 SV=2 6.79 1800.4 - 275212 - - - -3.6919 - 2.168 0.417 - 639.8 1 2 0 -0.0041 11 0 0 0 8.28E+06 5.91E+06 - - - 4.213 0.9995 221125_WJC_METTL3_EV_vs_WT_F04.06959.06959.2 0.0525 14-Aug K.QILSADDK.T sp|Q9Y3F4|STRAP_HUMAN 1 888.4553 1.38 42569 6959 2 888.454702 445.2349 Serine-threonine kinase receptor-associated protein OS=Homo sapiens OX=9606 GN=STRAP PE=1 SV=1 4.21 1801.1 - 3.69E+06 - - - -0.6303 - 1.421 0.408 - 299.2 1 2 0 -0.0006 8 0 0 0 2.73E+08 1.98E+08 - - - 3.114 0.9657 221125_WJC_METTL3_EV_vs_WT_F04.06962.06962.2 0.322 16-Aug R.ALDC[160.03]SSSIR.Q sp|O94776|MTA2_HUMAN 1 1007.4706 1.17 42572 6962 2 1007.466573 504.7426 Metastasis-associated protein MTA2 OS=Homo sapiens OX=9606 GN=MTA2 PE=1 SV=1 5.87 1801.3 - 907321 - - - -3.9912 - 1.379 0.18 - 203.9 1 2 0 -0.004 9 0 0 0 5.28E+07 4.51E+07 - - - 1.2989 0.9998 221125_WJC_METTL3_EV_vs_WT_F04.06971.06971.2 0.0266 16-Oct R.LLQEEEQER[166.11].R "sp|O14654|IRS4_HUMAN,tr|A0A804CF45|A0A804CF45_HUMAN" 2 1182.5756 1.12 42577 6971 2 1182.573696 592.2951 Insulin receptor substrate 4 OS=Homo sapiens OX=9606 GN=IRS4 PE=1 SV=1 4.09 1802.4 - 1.04E+06 - - - -1.6109 - 2.14 0.445 - 403.4 1 2 0 -0.0019 9 0 0 0 4.18E+08 3.74E+08 - - - 4.5282 0.9974 221125_WJC_METTL3_EV_vs_WT_F04.06976.06976.2 0.0089 18-Oct R.IQEAGTEVVK[136.11].A "sp|P40926|MDHM_HUMAN,tr|G3XAL0|G3XAL0_HUMAN" 2 1080.5906 1.66 42580 6976 2 1080.587006 541.3026 "Malate dehydrogenase, mitochondrial OS=Homo sapiens OX=9606 GN=MDH2 PE=1 SV=3" 4.53 1803 - 3.55E+06 - - - -3.363 - 2.079 0.28 - 231.8 1 2 0 -0.0036 10 0 0 0 1.49E+08 9.03E+07 - - - 3.1509 0.9172 221125_WJC_METTL3_EV_vs_WT_F04.06977.06977.2 0.647 14-Sep V.TDALNATR[166.11].A "sp|P10809|CH60_HUMAN,tr|A0A7I2V2X6|A0A7I2V2X6_HUMAN,tr|A0A7I2YQK6|A0A7I2YQK6_HUMAN,tr|A0A7I2V599|A0A7I2V599_HUMAN" 4 870.4435 2.81 42581 6977 2 870.442254 436.229 "60 kDa heat shock protein, mitochondrial OS=Homo sapiens OX=9606 GN=HSPD1 PE=1 SV=2" 5.5 1803 - 2.91E+06 - - - -1.3912 - 1.957 0.173 - 510.1 1 1 0 -0.0012 8 0 0 0 2.37E+08 8.43E+07 - - - 2.3433 0.9998 221125_WJC_METTL3_EV_vs_WT_F04.06978.06978.2 0.000593 16-Sep R.LLQEEEQER.R "sp|O14654|IRS4_HUMAN,tr|A0A804CF45|A0A804CF45_HUMAN" 2 1172.5673 1.12 42582 6978 2 1172.566822 587.2909 Insulin receptor substrate 4 OS=Homo sapiens OX=9606 GN=IRS4 PE=1 SV=1 4.09 1803.2 - 2.05E+06 - - - -0.4341 - 1.8 0.424 - 298.4 1 2 0 -0.0005 9 0 0 0 4.18E+08 3.74E+08 - - - 3.873 0.7663 221125_WJC_METTL3_EV_vs_WT_F04.06982.06982.2 3.15 12-Jul K.LKVSELK.E "sp|Q00839|HNRPU_HUMAN,sp|Q9ULH7|MRTFB_HUMAN,tr|A0A1W2PPS1|A0A1W2PPS1_HUMAN,tr|A0A1X7SBS1|A0A1X7SBS1_HUMAN" 4 815.5117 0.84 42583 6982 2 815.510335 408.7631 Heterogeneous nuclear ribonucleoprotein U OS=Homo sapiens OX=9606 GN=HNRNPU PE=1 SV=6 8.59 1803.7 - 530159 - - - -1.6174 - 1.212 0.125 - 133.7 4 2 1 -0.0013 7 0 0 0 7.06E+07 8.38E+07 - - - 0.3041 0.9798 221125_WJC_METTL3_EV_vs_WT_F04.06985.06985.2 0.435 16-Oct R.SALGPNVTK[136.11].L sp|Q8WU90|ZC3HF_HUMAN 1 893.5062 0.22 42585 6985 2 893.503386 447.7604 Zinc finger CCCH domain-containing protein 15 OS=Homo sapiens OX=9606 GN=ZC3H15 PE=1 SV=1 8.47 1804.1 - 1.31E+06 - - - -3.1292 - 1.444 0.153 - 228.8 1 2 0 -0.0028 9 0 0 0 1.79E+07 8.20E+07 - - - 1.2331 0.9869 221125_WJC_METTL3_EV_vs_WT_F04.06986.06986.2 0.0367 16-Aug K.LSEGLEGTK.Y "sp|Q5JPH6|SYEM_HUMAN,tr|H3BTB7|H3BTB7_HUMAN" 2 932.4815 0.13 42586 6986 2 932.480087 467.248 "Probable glutamate--tRNA ligase, mitochondrial OS=Homo sapiens OX=9606 GN=EARS2 PE=1 SV=2" 4.53 1804.2 - 871841 - - - -1.4896 - 1.668 0.046 - 138.9 2 2 0 -0.0014 9 0 0 0 2.45E+07 1.94E+08 - - - 0.726 0.9995 221125_WJC_METTL3_EV_vs_WT_F04.06993.06993.2 0.00236 14-Sep R.SVQTFADK.S tr|B1AK88|B1AK88_HUMAN 1 894.4447 0.84 42589 6993 2 894.44388 448.2296 F-actin-capping protein subunit beta OS=Homo sapiens OX=9606 GN=CAPZB PE=1 SV=1 5.55 1805 - 2.15E+06 - - - -0.9134 - 1.496 0.386 - 225.8 1 2 0 -0.0008 8 0 0 0 1.68E+08 1.99E+08 - - - 3.1066 0.9855 221125_WJC_METTL3_EV_vs_WT_F04.06994.06994.2 0.927 14-Sep K.SQIVTNVR.N "sp|O95757|HS74L_HUMAN,tr|D6RJ96|D6RJ96_HUMAN,tr|E9PDE8|E9PDE8_HUMAN" 3 915.5138 0.11 42590 6994 2 915.512387 458.7642 Heat shock 70 kDa protein 4L OS=Homo sapiens OX=9606 GN=HSPA4L PE=1 SV=3 9.47 1805.1 - 2.12E+06 - - - -1.5216 - 1.385 0.088 - 278.5 1 2 0 -0.0014 8 0 0 0 2.93E+07 2.76E+08 - - - 0.6728 0.9777 221125_WJC_METTL3_EV_vs_WT_F04.06995.06995.2 0.00306 18-Aug K.VENGQEPVIK[136.11].L "sp|P55265|DSRAD_HUMAN,tr|A0A3B3ITG9|A0A3B3ITG9_HUMAN,tr|A0A3B3IRQ9|A0A3B3IRQ9_HUMAN,tr|A0A3B3ISU1|A0A3B3ISU1_HUMAN,tr|A0A7P0Z4K3|A0A7P0Z4K3_HUMAN,tr|A0A7P0TA14|A0A7P0TA14_HUMAN,tr|A0A3B3ISX1|A0A3B3ISX1_HUMAN,tr|A0A7P0Z4F9|A0A7P0Z4F9_HUMAN" 8 1119.6015 0.96 42591 6995 2 1119.594674 560.808 Double-stranded RNA-specific adenosine deaminase OS=Homo sapiens OX=9606 GN=ADAR PE=1 SV=4 4.53 1805.2 - 1.17E+06 - - - -6.1316 - 1.676 0.335 - 250.5 1 2 0 -0.0069 10 0 0 0 7.46E+07 7.78E+07 - - - 2.9546 0.9978 221125_WJC_METTL3_EV_vs_WT_F04.06998.06998.2 0.27 14-Sep R.GPGPLQER[166.11].S "sp|P43243|MATR3_HUMAN,tr|A8MXP9|A8MXP9_HUMAN,tr|D6R991|D6R991_HUMAN,tr|A0A0R4J2E8|A0A0R4J2E8_HUMAN,tr|H0Y8T4|H0Y8T4_HUMAN,tr|D6REM6|D6REM6_HUMAN" 6 862.4536 1.59 42593 6998 2 862.452235 432.2341 Matrin-3 OS=Homo sapiens OX=9606 GN=MATR3 PE=1 SV=2 6 1805.6 - 7.63E+06 - - - -1.6244 - 1.619 0.221 - 342.8 1 2 0 -0.0014 8 0 0 0 1.24E+09 7.84E+08 - - - 2.126 0.9994 221125_WJC_METTL3_EV_vs_WT_F04.07002.07002.2 0.00296 12-Jul K.DNMALQR[166.11].V "sp|P38646|GRP75_HUMAN,tr|H0Y8K0|H0Y8K0_HUMAN,tr|A0A7I2V2G2|A0A7I2V2G2_HUMAN,tr|A0A7I2V3F7|A0A7I2V3F7_HUMAN,tr|A0A7I2YQB2|A0A7I2YQB2_HUMAN,tr|D6RCD7|D6RCD7_HUMAN" 6 856.4101 0.37 42594 7002 2 856.408167 429.2123 "Stress-70 protein, mitochondrial OS=Homo sapiens OX=9606 GN=HSPA9 PE=1 SV=2" 5.84 1806 - 1.18E+07 - - - -2.2057 - 1.668 0.439 - 414.3 1 2 0 -0.0019 7 0 0 0 2.23E+08 5.96E+08 - - - 3.904 0.9987 221125_WJC_METTL3_EV_vs_WT_F04.07003.07003.2 0.0109 16-Sep R.AVELDSESR.Y "sp|Q8WV92|MITD1_HUMAN,tr|F8WED5|F8WED5_HUMAN,tr|B8ZZL5|B8ZZL5_HUMAN,tr|A0A1W2PP14|A0A1W2PP14_HUMAN,tr|H7C3Q6|H7C3Q6_HUMAN" 5 1004.4775 1.17 42595 7003 2 1004.474649 503.246 MIT domain-containing protein 1 OS=Homo sapiens OX=9606 GN=MITD1 PE=1 SV=1 4.14 1806.1 - 4.13E+06 - - - -2.7925 - 1.961 0.327 - 314.6 1 2 0 -0.0028 9 0 0 0 1.05E+08 8.93E+07 - - - 3.4037 0.9223 221125_WJC_METTL3_EV_vs_WT_F04.07004.07004.2 7.19 14-Jun K.VTHLSETR[166.11].S "sp|Q9Y2H2|SAC2_HUMAN,tr|A0A3B3IRJ9|A0A3B3IRJ9_HUMAN,tr|A0A3B3ITL0|A0A3B3ITL0_HUMAN" 3 951.5013 1.38 42596 7004 2 951.500704 476.7579 Phosphatidylinositide phosphatase SAC2 OS=Homo sapiens OX=9606 GN=INPP5F PE=1 SV=3 6.72 1806.2 - 1.89E+06 - - - -0.6411 - 1.161 0.03 - 67.1 8 2 0 -0.0006 8 0 0 0 1.04E+08 7.55E+07 - - - -0.6908 0.9936 221125_WJC_METTL3_EV_vs_WT_F04.07009.07009.2 0.00256 12-Jul K.FAANINK[136.11].E "sp|P14868|SYDC_HUMAN,tr|C9JQM9|C9JQM9_HUMAN,tr|C9J7S3|C9J7S3_HUMAN,tr|H7C278|H7C278_HUMAN,tr|C9JLC1|C9JLC1_HUMAN" 5 784.4323 0.36 42599 7009 2 784.429639 393.2234 "Aspartate--tRNA ligase, cytoplasmic OS=Homo sapiens OX=9606 GN=DARS1 PE=1 SV=2" 8.75 1806.7 - 1.49E+06 - - - -3.377 - 1.469 0.275 - 121.9 1 2 0 -0.0026 7 0 0 0 3.24E+08 9.02E+08 - - - 2.2899 0.9958 221125_WJC_METTL3_EV_vs_WT_F04.07017.07017.2 0.000463 16-Aug K.TEYDAVAEK[136.11].A "sp|Q9NTJ3|SMC4_HUMAN,tr|E9PD53|E9PD53_HUMAN" 2 1032.4855 0.74 42601 7017 2 1032.480732 517.25 Structural maintenance of chromosomes protein 4 OS=Homo sapiens OX=9606 GN=SMC4 PE=1 SV=2 4.14 1807.9 - 1.41E+06 - - - -4.6238 - 1.748 0.404 - 237 1 2 0 -0.0048 9 0 0 0 2.68E+07 3.64E+07 - - - 3.6391 0.998 221125_WJC_METTL3_EV_vs_WT_F04.07019.07019.2 0.000114 18-Nov K.VGAAEEELQK[136.11].S "sp|Q9P2E9|RRBP1_HUMAN,tr|A0A087WU26|A0A087WU26_HUMAN,tr|A0A087WVV2|A0A087WVV2_HUMAN,tr|F8W7S5|F8W7S5_HUMAN" 4 1080.5543 1.19 42602 7019 2 1080.549501 541.2844 Ribosome-binding protein 1 OS=Homo sapiens OX=9606 GN=RRBP1 PE=1 SV=5 4.25 1808.1 - 1.05E+06 - - - -4.3987 - 1.974 0.466 - 402.1 1 2 0 -0.0048 10 0 0 0 8.79E+07 7.36E+07 - - - 4.3796 0.9991 221125_WJC_METTL3_EV_vs_WT_F04.07020.07020.2 0.00234 20-Sep K.SVQVNGAATVR.T "tr|H0Y641|H0Y641_HUMAN,tr|H0Y4V9|H0Y4V9_HUMAN" 2 1100.5938 0.95 42603 7020 2 1100.590838 551.3042 La-related protein 4B (Fragment) OS=Homo sapiens OX=9606 GN=LARP4B PE=1 SV=2 9.47 1808.2 - 461839 - - - -2.7104 - 1.799 0.438 - 181.4 1 2 0 -0.003 11 0 0 0 8.99E+06 9.45E+06 - - - 3.8637 0.9946 221125_WJC_METTL3_EV_vs_WT_F04.07022.07022.2 0.629 16-Aug K.ALLQSSASR.K sp|Q9UQ80|PA2G4_HUMAN 1 931.5087 0.28 42605 7022 2 931.507557 466.7616 Proliferation-associated protein 2G4 OS=Homo sapiens OX=9606 GN=PA2G4 PE=1 SV=3 9.79 1808.4 - 781063 - - - -1.2206 - 1.458 0.152 - 126.6 1 2 0 -0.0011 9 0 0 0 9.81E+07 3.47E+08 - - - 1.2542 0.9984 221125_WJC_METTL3_EV_vs_WT_F04.07025.07025.2 0.00106 16-Sep R.EVDAEYEAR[166.11].S "sp|Q8N6H7|ARFG2_HUMAN,tr|E9PMU9|E9PMU9_HUMAN,tr|H0YDN9|H0YDN9_HUMAN,tr|G5E9L0|G5E9L0_HUMAN,tr|A0A0D9SF70|A0A0D9SF70_HUMAN" 5 1090.4806 1.22 42606 7025 2 1090.47626 546.2476 ADP-ribosylation factor GTPase-activating protein 2 OS=Homo sapiens OX=9606 GN=ARFGAP2 PE=1 SV=1 4 1808.8 - 1.26E+06 - - - -4.0147 - 1.652 0.52 - 403.5 1 2 0 -0.0044 9 0 0 0 2.06E+08 1.69E+08 - - - 4.3326 0.9997 221125_WJC_METTL3_EV_vs_WT_F04.07028.07028.2 0.00267 16-Sep K.TEYDAVAEK.A "sp|Q9NTJ3|SMC4_HUMAN,tr|E9PD53|E9PD53_HUMAN" 2 1024.4713 0.74 42608 7028 2 1024.469596 513.2429 Structural maintenance of chromosomes protein 4 OS=Homo sapiens OX=9606 GN=SMC4 PE=1 SV=2 4.14 1809.1 - 1.12E+06 - - - -1.6692 - 2.049 0.434 - 349 1 2 0 -0.0017 9 0 0 0 2.68E+07 3.62E+07 - - - 4.3213 0.9993 221125_WJC_METTL3_EV_vs_WT_F04.07029.07029.2 8.58E-07 20-Nov K.FATC[160.03]SDDGTVR.L "sp|Q9C0J8|WDR33_HUMAN,tr|C9J8B4|C9J8B4_HUMAN" 2 1227.519 1.61 42609 7029 2 1227.514894 614.7668 pre-mRNA 3' end processing protein WDR33 OS=Homo sapiens OX=9606 GN=WDR33 PE=1 SV=2 4.21 1809.3 - 947481 - - - -3.3458 - 1.966 0.54 - 429.2 1 2 0 -0.0041 11 0 0 0 2.49E+07 1.54E+07 - - - 4.8569 0.9997 221125_WJC_METTL3_EV_vs_WT_F04.07033.07033.2 0.00103 16-Aug R.EVDAEYEAR.S "sp|Q8N6H7|ARFG2_HUMAN,tr|E9PMU9|E9PMU9_HUMAN,tr|H0YDN9|H0YDN9_HUMAN,tr|G5E9L0|G5E9L0_HUMAN,tr|A0A0D9SF70|A0A0D9SF70_HUMAN" 5 1080.4724 1.22 42611 7033 2 1080.47091 541.2435 ADP-ribosylation factor GTPase-activating protein 2 OS=Homo sapiens OX=9606 GN=ARFGAP2 PE=1 SV=1 4 1809.8 - 2.79E+06 - - - -1.3494 - 1.592 0.466 - 317.1 1 2 0 -0.0015 9 0 0 0 2.06E+08 1.69E+08 - - - 3.8277 0.9994 221125_WJC_METTL3_EV_vs_WT_F04.07034.07034.2 2.12E-06 20-Oct K.FATC[160.03]SDDGTVR[166.11].L "sp|Q9C0J8|WDR33_HUMAN,tr|C9J8B4|C9J8B4_HUMAN" 2 1237.5273 1.61 42612 7034 2 1237.522794 619.7709 pre-mRNA 3' end processing protein WDR33 OS=Homo sapiens OX=9606 GN=WDR33 PE=1 SV=2 4.21 1809.9 - 830673 - - - -3.6177 - 1.886 0.664 - 385.5 1 2 0 -0.0045 11 0 0 0 2.49E+07 1.54E+07 - - - 5.6603 0.9943 221125_WJC_METTL3_EV_vs_WT_F04.07036.07036.2 0.0035 16-Oct K.VSNLQVSPK[136.11].S "sp|O00443|P3C2A_HUMAN,tr|A0A0C4DGF9|A0A0C4DGF9_HUMAN" 2 978.5589 1.14 42614 7036 2 978.554539 490.2867 Phosphatidylinositol 4-phosphate 3-kinase C2 domain-containing subunit alpha OS=Homo sapiens OX=9606 GN=PIK3C2A PE=1 SV=2 8.72 1810.1 - 800136 - - - -4.5025 - 1.882 0.314 - 257.8 1 2 0 -0.0044 9 0 0 0 1.03E+08 9.04E+07 - - - 3.1882 0.9981 221125_WJC_METTL3_EV_vs_WT_F04.07042.07042.2 0.0701 16-Nov K.SLDGVTNDR[166.11].T "sp|Q9UBM7|DHCR7_HUMAN,tr|E9PIP9|E9PIP9_HUMAN,tr|E9PJ54|E9PJ54_HUMAN,tr|E9PRL8|E9PRL8_HUMAN,tr|E9PM00|E9PM00_HUMAN,tr|A0A804HI25|A0A804HI25_HUMAN,tr|A0A804HJQ7|A0A804HJQ7_HUMAN,tr|A0A804HJI8|A0A804HJI8_HUMAN,tr|A0A804HL56|A0A804HL56_HUMAN,tr|E9PQ71|E9PQ71_HUMAN" 10 985.4704 1.17 42618 7042 2 985.466617 493.7425 7-dehydrocholesterol reductase OS=Homo sapiens OX=9606 GN=DHCR7 PE=1 SV=1 4.21 1810.9 - 1.30E+06 - - - -3.8469 - 2.201 0.35 - 323.3 1 2 0 -0.0038 9 0 0 0 5.73E+07 4.91E+07 - - - 3.9073 0.9993 221125_WJC_METTL3_EV_vs_WT_F04.07043.07043.2 0.00698 12-Jul K.DNMALQR.V "sp|P38646|GRP75_HUMAN,tr|H0Y8K0|H0Y8K0_HUMAN,tr|A0A7I2V2G2|A0A7I2V2G2_HUMAN,tr|A0A7I2V3F7|A0A7I2V3F7_HUMAN,tr|A0A7I2YQB2|A0A7I2YQB2_HUMAN,tr|D6RCD7|D6RCD7_HUMAN" 6 846.4018 0.39 42619 7043 2 846.399679 424.2082 "Stress-70 protein, mitochondrial OS=Homo sapiens OX=9606 GN=HSPA9 PE=1 SV=2" 5.84 1810.9 - 8.31E+06 - - - -2.4894 - 1.633 0.454 - 379.9 1 2 0 -0.0021 7 0 0 0 2.30E+08 5.97E+08 - - - 3.9475 0.9996 221125_WJC_METTL3_EV_vs_WT_F04.07044.07044.2 0.00265 14-Jul R.GNDTFGPR[166.11].A "sp|Q9ULX6|AKP8L_HUMAN,tr|A0A7P0T9N5|A0A7P0T9N5_HUMAN,tr|A0A7P0TAD3|A0A7P0TAD3_HUMAN,tr|V9GZ50|V9GZ50_HUMAN,tr|A0A7P0TBP0|A0A7P0TBP0_HUMAN,tr|A0A7P0TAJ5|A0A7P0TAJ5_HUMAN,tr|A0A7P0TAE3|A0A7P0TAE3_HUMAN,tr|A0A7P0T847|A0A7P0T847_HUMAN" 8 872.4016 0.88 42620 7044 2 872.400795 437.2081 A-kinase anchor protein 8-like OS=Homo sapiens OX=9606 GN=AKAP8L PE=1 SV=4 5.84 1811 - 1.12E+06 - - - -0.9227 - 1.482 0.426 - 251.5 1 2 0 -0.0008 8 0 0 0 6.48E+07 7.36E+07 - - - 3.3736 0.8835 221125_WJC_METTL3_EV_vs_WT_F04.07050.07050.2 0.467 12-Sep S.KLQELVR.Y "sp|Q9NY15|STAB1_HUMAN,sp|Q8ND83|SLAI1_HUMAN,tr|A0A0A0MSS3|A0A0A0MSS3_HUMAN" 3 884.5444 1.14 42624 7050 2 884.543357 443.2795 Stabilin-1 OS=Homo sapiens OX=9606 GN=STAB1 PE=1 SV=3 8.75 1811.7 - 1.01E+06 - - - -1.1237 - 1.722 0.155 - 386.1 1 1 0 -0.001 7 0 0 0 3.62E+07 3.19E+07 - - - 1.9076 0.9443 221125_WJC_METTL3_EV_vs_WT_F04.07057.07057.2 0.0537 16-Jul Q.GLVLDHGAR.H "sp|Q92526|TCPW_HUMAN,sp|P40227|TCPZ_HUMAN,tr|J3KRI6|J3KRI6_HUMAN" 3 936.5141 0.31 42629 7057 2 936.515055 469.2643 T-complex protein 1 subunit zeta-2 OS=Homo sapiens OX=9606 GN=CCT6B PE=1 SV=5 6.74 1812.5 - 5.34E+06 - - - 1.0048 - 1.678 0.285 - 180.9 1 1 0 0.0009 9 0 0 0 3.00E+08 9.69E+08 - - - 2.6432 0.9997 221125_WJC_METTL3_EV_vs_WT_F04.07058.07058.2 0.00113 14-Aug K.MSNADFAK.L "sp|Q15020|SART3_HUMAN,tr|A0A499FI31|A0A499FI31_HUMAN" 2 882.3906 1.92 42630 7058 2 882.389977 442.2026 Squamous cell carcinoma antigen recognized by T-cells 3 OS=Homo sapiens OX=9606 GN=SART3 PE=1 SV=1 5.59 1812.6 - 1.28E+06 - - - -0.6528 - 1.474 0.45 - 199.7 1 2 0 -0.0006 8 0 0 0 4.07E+07 2.12E+07 - - - 3.5346 0.9998 221125_WJC_METTL3_EV_vs_WT_F04.07067.07067.2 3.72E-05 16-Nov R.VTDALNATR.A "sp|P10809|CH60_HUMAN,tr|A0A7I2V2X6|A0A7I2V2X6_HUMAN,tr|A0A7I2YQK6|A0A7I2YQK6_HUMAN,tr|A0A7I2V599|A0A7I2V599_HUMAN" 4 959.5036 1.28 42636 7067 2 959.502158 480.7591 "60 kDa heat shock protein, mitochondrial OS=Homo sapiens OX=9606 GN=HSPD1 PE=1 SV=2" 5.81 1813.7 - 2.23E+07 - - - -1.5122 - 2.32 0.459 - 503.4 1 2 0 -0.0015 9 0 0 0 3.40E+10 2.66E+10 - - - 4.8654 0.9986 221125_WJC_METTL3_EV_vs_WT_F04.07068.07068.2 0.000113 18-Sep K.VENGQEPVIK.L "sp|P55265|DSRAD_HUMAN,tr|A0A3B3ITG9|A0A3B3ITG9_HUMAN,tr|A0A3B3IRQ9|A0A3B3IRQ9_HUMAN,tr|A0A3B3ISU1|A0A3B3ISU1_HUMAN,tr|A0A7P0Z4K3|A0A7P0Z4K3_HUMAN,tr|A0A7P0TA14|A0A7P0TA14_HUMAN,tr|A0A3B3ISX1|A0A3B3ISX1_HUMAN,tr|A0A7P0Z4F9|A0A7P0Z4F9_HUMAN" 8 1111.5873 0.96 42637 7068 2 1111.58495 556.8009 Double-stranded RNA-specific adenosine deaminase OS=Homo sapiens OX=9606 GN=ADAR PE=1 SV=4 4.53 1813.8 - 952372 - - - -2.1492 - 1.956 0.262 - 292.9 1 2 0 -0.0024 10 0 0 0 7.46E+07 7.78E+07 - - - 2.8481 0.9999 221125_WJC_METTL3_EV_vs_WT_F04.07069.07069.2 6.01E-05 22-Dec R.LLQAETASNSAR.A "sp|Q14980|NUMA1_HUMAN,tr|H0YFY6|H0YFY6_HUMAN" 2 1259.647 1.08 42638 7069 2 1259.646092 630.8308 Nuclear mitotic apparatus protein 1 OS=Homo sapiens OX=9606 GN=NUMA1 PE=1 SV=2 6 1814 - 352080 - - - -0.7042 - 2.276 0.486 - 556.2 1 2 0 -0.0009 12 0 0 0 1.58E+07 1.46E+07 - - - 4.7942 0.9999 221125_WJC_METTL3_EV_vs_WT_F04.07070.07070.2 0.00036 20-Oct R.FEEAAGAAPC[160.03]R.L "sp|Q9Y4P3|TBL2_HUMAN,tr|E9PF19|E9PF19_HUMAN,tr|Q96E41|Q96E41_HUMAN" 3 1177.5186 1.2 42639 7070 2 1177.517509 589.7666 Transducin beta-like protein 2 OS=Homo sapiens OX=9606 GN=TBL2 PE=1 SV=1 4.53 1814.1 - 333100 - - - -0.9325 - 2.118 0.52 - 345.3 1 2 0 -0.0011 11 0 0 0 1.51E+07 1.26E+07 - - - 4.9116 0.9998 221125_WJC_METTL3_EV_vs_WT_F04.07071.07071.2 0.000215 20-Aug R.FEEAAGAAPC[160.03]R[166.11].L "sp|Q9Y4P3|TBL2_HUMAN,tr|E9PF19|E9PF19_HUMAN,tr|Q96E41|Q96E41_HUMAN" 3 1187.5269 1.2 42640 7071 2 1187.525595 594.7707 Transducin beta-like protein 2 OS=Homo sapiens OX=9606 GN=TBL2 PE=1 SV=1 4.53 1814.2 - 342244 - - - -1.0796 - 1.886 0.493 - 237.1 1 2 0 -0.0013 11 0 0 0 1.51E+07 1.26E+07 - - - 4.3983 0.9996 221125_WJC_METTL3_EV_vs_WT_F04.07074.07074.2 0.000312 16-Sep K.C[160.03]DTVLGSSR.S "sp|Q86UP3|ZFHX4_HUMAN,sp|Q15911|ZFHX3_HUMAN,tr|E5RI93|E5RI93_HUMAN,tr|E7EVZ1|E7EVZ1_HUMAN" 4 993.4549 0.06 42641 7074 2 993.453372 497.7347 Zinc finger homeobox protein 4 OS=Homo sapiens OX=9606 GN=ZFHX4 PE=1 SV=1 5.83 1814.6 - 313850 - - - -1.5824 - 1.807 0.433 - 196.9 1 2 0 -0.0016 9 0 0 0 1.09E+07 1.73E+08 - - - 3.9504 0.7653 221125_WJC_METTL3_EV_vs_WT_F04.07076.07076.2 0.202 14-Jun G.LVLDHGAR[166.11].H "sp|Q92526|TCPW_HUMAN,sp|P40227|TCPZ_HUMAN,tr|J3KRI6|J3KRI6_HUMAN" 3 889.5009 0.6 42642 7076 2 889.500229 445.7577 T-complex protein 1 subunit zeta-2 OS=Homo sapiens OX=9606 GN=CCT6B PE=1 SV=5 6.74 1814.8 - 738486 - - - -0.7768 - 1.164 0.225 - 123 1 1 0 -0.0007 8 0 0 0 1.16E+07 1.92E+07 - - - 1.1606 0.9998 221125_WJC_METTL3_EV_vs_WT_F04.07080.07080.2 6.47E-06 20-Sep K.TPGPGAQSALR[166.11].A "sp|P62263|RS14_HUMAN,tr|A0A2R8Y811|A0A2R8Y811_HUMAN,tr|E5RH77|E5RH77_HUMAN" 3 1063.565 1.41 42644 7080 2 1063.563791 532.7898 40S ribosomal protein S14 OS=Homo sapiens OX=9606 GN=RPS14 PE=1 SV=3 9.41 1815.4 - 6.21E+07 - - - -1.1151 - 1.825 0.516 - 283.9 1 2 0 -0.0012 11 0 0 0 1.22E+10 8.67E+09 - - - 4.4792 0.9997 221125_WJC_METTL3_EV_vs_WT_F04.07083.07083.2 5.49E-05 16-Oct K.VSNLQVSPK.S "sp|O00443|P3C2A_HUMAN,tr|A0A0C4DGF9|A0A0C4DGF9_HUMAN" 2 970.5447 1.16 42645 7083 2 970.543739 486.2796 Phosphatidylinositol 4-phosphate 3-kinase C2 domain-containing subunit alpha OS=Homo sapiens OX=9606 GN=PIK3C2A PE=1 SV=2 8.72 1815.8 - 3.71E+06 - - - -1.0365 - 1.997 0.375 - 241 1 2 0 -0.001 9 0 0 0 1.03E+08 8.89E+07 - - - 3.8114 0.9991 221125_WJC_METTL3_EV_vs_WT_F04.07085.07085.2 0.015 16-Aug K.EVQDGIAPR[166.11].M sp|P45974|UBP5_HUMAN 1 993.5119 1.08 42646 7085 2 993.510963 497.7632 Ubiquitin carboxyl-terminal hydrolase 5 OS=Homo sapiens OX=9606 GN=USP5 PE=1 SV=2 4.37 1816 - 793128 - - - -0.922 - 1.561 0.306 - 277.5 1 2 0 -0.0009 9 0 0 0 2.30E+07 2.13E+07 - - - 2.5892 0.9979 221125_WJC_METTL3_EV_vs_WT_F04.07094.07094.2 0.124 16-Jun K.AQLAETVSR[166.11].H sp|Q9HAJ7|SP30L_HUMAN 1 983.5275 2.19 42649 7094 2 983.527199 492.771 Histone deacetylase complex subunit SAP30L OS=Homo sapiens OX=9606 GN=SAP30L PE=1 SV=1 6.05 1817.3 - 1.01E+06 - - - -0.3355 - 1.476 0.244 - 149.4 3 2 0 -0.0003 9 0 0 0 7.31E+07 3.35E+07 - - - 1.7563 0.9999 221125_WJC_METTL3_EV_vs_WT_F04.07097.07097.2 0.000788 22-Nov R.LLQAETASNSAR[166.11].A "sp|Q14980|NUMA1_HUMAN,tr|H0YFY6|H0YFY6_HUMAN" 2 1269.6552 1.13 42651 7097 2 1269.654299 635.8349 Nuclear mitotic apparatus protein 1 OS=Homo sapiens OX=9606 GN=NUMA1 PE=1 SV=2 6 1817.6 - 332187 - - - -0.7482 - 2.246 0.488 - 528.4 1 2 0 -0.0009 12 0 0 0 1.58E+07 1.40E+07 - - - 4.7741 0.9875 221125_WJC_METTL3_EV_vs_WT_F04.07098.07098.2 0.0715 18-Sep R.LLEAAAQSTK[136.11].G "sp|Q15149|PLEC_HUMAN,tr|H0YDN1|H0YDN1_HUMAN" 2 1038.5801 2.85 42652 7098 2 1038.575695 520.2973 Plectin OS=Homo sapiens OX=9606 GN=PLEC PE=1 SV=3 6 1817.8 - 198713 - - - -4.2173 - 1.734 0.226 - 208 1 2 0 -0.0044 10 0 0 0 1.15E+07 4.04E+06 - - - 2.2453 0.9991 221125_WJC_METTL3_EV_vs_WT_F04.07101.07101.2 0.0945 14-Aug R.K[136.11]LPEEVVK[136.11].K "sp|O75643|U520_HUMAN,tr|A0A494C1A5|A0A494C1A5_HUMAN" 2 956.5877 1.8 42653 7101 2 956.58679 479.3011 U5 small nuclear ribonucleoprotein 200 kDa helicase OS=Homo sapiens OX=9606 GN=SNRNP200 PE=1 SV=2 6.14 1818.1 - 1.50E+06 - - - -0.9858 - 1.5 0.322 - 187.3 1 2 0 -0.0009 8 0 0 0 1.61E+08 8.97E+07 - - - 2.6419 0.987 221125_WJC_METTL3_EV_vs_WT_F04.07102.07102.2 0.647 16-Jul K.SALGAVSQR.L "sp|Q9BSJ6|PIMRE_HUMAN,tr|I3L419|I3L419_HUMAN" 2 887.4825 1.22 42654 7102 2 887.480483 444.7485 Protein PIMREG OS=Homo sapiens OX=9606 GN=PIMREG PE=1 SV=1 9.47 1818.2 - 1.15E+06 - - - -2.2491 - 1.651 0.081 - 136 1 2 0 -0.002 9 0 0 0 5.10E+07 4.18E+07 - - - 1.0892 0.9738 221125_WJC_METTL3_EV_vs_WT_F04.07104.07104.2 0.106 16-Sep Q.GLVLDHGAR[166.11].H "sp|Q92526|TCPW_HUMAN,sp|P40227|TCPZ_HUMAN,tr|J3KRI6|J3KRI6_HUMAN" 3 946.5224 0.31 42655 7104 2 946.521841 474.2685 T-complex protein 1 subunit zeta-2 OS=Homo sapiens OX=9606 GN=CCT6B PE=1 SV=5 6.74 1818.4 - 2.38E+07 - - - -0.5737 - 1.91 0.307 - 405.2 1 1 0 -0.0005 9 0 0 0 3.00E+08 9.71E+08 - - - 3.1804 0.9994 221125_WJC_METTL3_EV_vs_WT_F04.07106.07106.2 0.0223 14-Aug K.IVNLGSSK.T sp|Q7RTV0|PHF5A_HUMAN 1 816.4705 1.03 42656 7106 2 816.470273 409.2425 PHD finger-like domain-containing protein 5A OS=Homo sapiens OX=9606 GN=PHF5A PE=1 SV=1 8.75 1818.7 - 2.83E+06 - - - -0.3001 - 1.887 0.261 - 168.4 1 2 0 -0.0002 8 0 0 0 6.98E+07 6.80E+07 - - - 2.8838 0.885 221125_WJC_METTL3_EV_vs_WT_F04.07107.07107.2 4.37 14-May K.IVNLGSSK[136.11].T sp|Q7RTV0|PHF5A_HUMAN 1 824.4847 1.03 42657 7107 2 824.484827 413.2496 PHD finger-like domain-containing protein 5A OS=Homo sapiens OX=9606 GN=PHF5A PE=1 SV=1 8.75 1818.7 - 2.61E+06 - - - 0.1322 - 1.108 0.012 - 68.8 9 2 0 0.0001 8 0 0 0 6.98E+07 6.80E+07 - - - -0.9874 0.9993 221125_WJC_METTL3_EV_vs_WT_F04.07112.07112.2 0.0104 12-Aug R.QSSVSFR.S "sp|P13647|K2C5_HUMAN,tr|F8W0C6|F8W0C6_HUMAN,tr|F8VV57|F8VV57_HUMAN,tr|F8VU69|F8VU69_HUMAN" 4 809.4032 185.03 42660 7112 2 809.402648 405.7089 "Keratin, type II cytoskeletal 5 OS=Homo sapiens OX=9606 GN=KRT5 PE=1 SV=3" 9.75 1819.3 - 2.18E+06 - - - -0.64 - 1.553 0.306 - 236 1 2 0 -0.0005 7 0 0 0 8.92E+08 4.82E+06 - - - 2.6957 0.9997 221125_WJC_METTL3_EV_vs_WT_F04.07113.07113.2 0.000996 14-Jul K.ISDSEGFK.A sp|P23246|SFPQ_HUMAN 1 881.4131 0.81 42661 7113 2 881.413478 441.7138 "Splicing factor, proline- and glutamine-rich OS=Homo sapiens OX=9606 GN=SFPQ PE=1 SV=2" 4.37 1819.4 - 925224 - - - 0.4708 - 1.593 0.428 - 107.4 1 2 0 0.0004 8 0 0 0 2.15E+08 2.65E+08 - - - 3.6064 0.9768 221125_WJC_METTL3_EV_vs_WT_F04.07116.07116.2 1.77 14-Jul R.KLPEEVVK.K "sp|O75643|U520_HUMAN,tr|A0A494C1A5|A0A494C1A5_HUMAN" 2 940.5593 1.8 42662 7116 2 940.560298 471.2869 U5 small nuclear ribonucleoprotein 200 kDa helicase OS=Homo sapiens OX=9606 GN=SNRNP200 PE=1 SV=2 6.14 1819.8 - 3.01E+06 - - - 1.026 - 1.215 0.084 - 160.4 1 2 0 0.001 8 0 0 0 1.62E+08 8.98E+07 - - - 0.2485 0.9993 221125_WJC_METTL3_EV_vs_WT_F04.07117.07117.2 0.0161 14-Jul K.ISDSEGFK[136.11].A sp|P23246|SFPQ_HUMAN 1 889.4273 0.81 42663 7117 2 889.427512 445.7209 "Splicing factor, proline- and glutamine-rich OS=Homo sapiens OX=9606 GN=SFPQ PE=1 SV=2" 4.37 1819.8 - 2.35E+06 - - - 0.28 - 1.382 0.368 - 95.6 1 2 0 0.0003 8 0 0 0 2.15E+08 2.64E+08 - - - 2.7347 0.9998 221125_WJC_METTL3_EV_vs_WT_F04.07118.07118.2 0.000562 18-Nov R.AEQLAAEAER.D sp|Q9HCS7|SYF1_HUMAN 1 1086.5306 0.74 42664 7118 2 1086.531099 544.2726 Pre-mRNA-splicing factor SYF1 OS=Homo sapiens OX=9606 GN=XAB2 PE=1 SV=2 4.25 1820 - 703550 - - - 0.5034 - 2.347 0.41 - 663.3 1 2 0 0.0005 10 0 0 0 2.25E+07 3.04E+07 - - - 4.4505 0.9387 221125_WJC_METTL3_EV_vs_WT_F04.07119.07119.2 1.89 12-Apr R.VPSPEPR[166.11].L sp|Q9P2P6|STAR9_HUMAN 1 790.4213 0.03 42665 7119 2 790.421329 396.2179 StAR-related lipid transfer protein 9 OS=Homo sapiens OX=9606 GN=STARD9 PE=1 SV=3 5.97 1820.1 - 486718 - - - 0.0708 - 1.009 0.129 - 45.6 21 2 0 0.0001 7 0 0 0 4.00E+05 1.48E+07 - - - -0.5685 0.9983 221125_WJC_METTL3_EV_vs_WT_F04.07122.07122.2 0.00634 12-Aug K.TDFVNSR.T sp|Q99959|PKP2_HUMAN 1 837.3981 0.5 42666 7122 2 837.398344 419.7063 Plakophilin-2 OS=Homo sapiens OX=9606 GN=PKP2 PE=1 SV=2 5.5 1820.5 - 717892 - - - 0.3141 - 1.542 0.206 - 386.6 1 2 0 0.0003 7 0 0 0 2.33E+07 4.69E+07 - - - 1.9347 0.9994 221125_WJC_METTL3_EV_vs_WT_F04.07123.07123.2 8.05E-05 12-Aug K.TYYYNNR.T "sp|O14776|TCRG1_HUMAN,tr|A0A7P0T8N8|A0A7P0T8N8_HUMAN,tr|G3V220|G3V220_HUMAN" 3 992.4352 0.04 42667 7123 2 992.436928 497.2249 Transcription elongation regulator 1 OS=Homo sapiens OX=9606 GN=TCERG1 PE=1 SV=2 8.16 1820.6 - 705885 - - - 1.7462 - 1.371 0.481 - 247.7 1 2 0 0.0017 7 0 0 0 1.31E+07 3.34E+08 - - - 3.5929 0.9978 221125_WJC_METTL3_EV_vs_WT_F04.07124.07124.2 0.0805 16-Aug K.SALGAVSQR[166.11].L "sp|Q9BSJ6|PIMRE_HUMAN,tr|I3L419|I3L419_HUMAN" 2 897.4907 1.23 42668 7124 2 897.491895 449.7527 Protein PIMREG OS=Homo sapiens OX=9606 GN=PIMREG PE=1 SV=1 9.47 1820.7 - 1.84E+06 - - - 1.2769 - 1.513 0.265 - 178.8 2 2 0 0.0011 9 0 0 0 5.05E+07 4.12E+07 - - - 2.0615 0.9998 221125_WJC_METTL3_EV_vs_WT_F04.07125.07125.2 0.0451 18-Nov R.AEQLAAEAER[166.11].D sp|Q9HCS7|SYF1_HUMAN 1 1096.5388 1.34 42669 7125 2 1096.538285 549.2767 Pre-mRNA-splicing factor SYF1 OS=Homo sapiens OX=9606 GN=XAB2 PE=1 SV=2 4.25 1820.8 - 645507 - - - -0.4897 - 2.268 0.391 - 700.1 1 2 0 -0.0005 10 0 0 0 2.08E+07 1.55E+07 - - - 4.2146 0.9992 221125_WJC_METTL3_EV_vs_WT_F04.07126.07126.2 0.000681 16-Oct K.TEDEVLTSK.G sp|Q9BQ61|TRIR_HUMAN 1 1020.4975 0.52 42670 7126 2 1020.498311 511.256 Telomerase RNA component interacting RNase OS=Homo sapiens OX=9606 GN=TRIR PE=1 SV=1 4.14 1820.9 - 398059 - - - 0.7751 - 1.636 0.315 - 361.6 1 2 0 0.0008 9 0 0 0 3.59E+07 6.92E+07 - - - 2.7915 0.9913 221125_WJC_METTL3_EV_vs_WT_F04.07131.07131.2 0.51 14-Jun R.R[166.11]LAEALPK[136.11].Q "sp|P20290|BTF3_HUMAN,tr|A0A7I2V3T6|A0A7I2V3T6_HUMAN,tr|D6RDG3|D6RDG3_HUMAN,tr|A0A7I2V5Y3|A0A7I2V5Y3_HUMAN,tr|H0Y9Y1|H0Y9Y1_HUMAN,tr|A0A7I2YQL2|A0A7I2YQL2_HUMAN" 6 914.5668 0.98 42673 7131 2 914.567027 458.2907 Transcription factor BTF3 OS=Homo sapiens OX=9606 GN=BTF3 PE=1 SV=1 8.75 1821.4 - 5.26E+06 - - - 0.2252 - 1.201 0.154 - 172.7 1 2 0 0.0002 8 0 0 0 9.11E+07 9.29E+07 - - - 0.7308 0.9936 221125_WJC_METTL3_EV_vs_WT_F04.07132.07132.2 1.03 14-Jun K.ESGLISTK[136.11].K sp|Q9NWT1|PK1IP_HUMAN 1 841.4636 0.12 42674 7132 2 841.464685 421.7391 p21-activated protein kinase-interacting protein 1 OS=Homo sapiens OX=9606 GN=PAK1IP1 PE=1 SV=2 6.1 1821.5 - 847482 - - - 1.2324 - 1.265 0.198 - 119.7 1 2 0 0.001 8 0 0 0 4.31E+06 3.54E+07 - - - 1.2121 0.9983 221125_WJC_METTL3_EV_vs_WT_F04.07134.07134.2 0.1 14-Jul R.C[160.03]PYGVTC[160.03]R.F sp|Q96G46|DUS3L_HUMAN 1 1011.4266 0.99 42676 7134 2 1011.424328 506.7206 tRNA-dihydrouridine(47) synthase [NAD(P)(+)]-like OS=Homo sapiens OX=9606 GN=DUS3L PE=1 SV=2 8.06 1821.8 - 150641 - - - -2.2671 - 1.143 0.447 - 112 1 2 0 -0.0023 8 0 0 0 5.50E+06 5.54E+06 - - - 2.7449 0.9998 221125_WJC_METTL3_EV_vs_WT_F04.07137.07137.2 0.0219 20-Oct K.TPGPGAQSALR.A "sp|P62263|RS14_HUMAN,tr|A0A2R8Y811|A0A2R8Y811_HUMAN,tr|E5RH77|E5RH77_HUMAN" 3 1053.5567 1.41 42678 7137 2 1053.557798 527.7856 40S ribosomal protein S14 OS=Homo sapiens OX=9606 GN=RPS14 PE=1 SV=3 9.41 1822.1 - 3.38E+06 - - - 1.0355 - 2.034 0.468 - 360.4 1 2 0 0.0011 11 0 0 0 1.22E+10 8.67E+09 - - - 4.418 0.9987 221125_WJC_METTL3_EV_vs_WT_F04.07140.07140.2 0.0076 12-Aug K.TYYYNNR[166.11].T "sp|O14776|TCRG1_HUMAN,tr|A0A7P0T8N8|A0A7P0T8N8_HUMAN,tr|G3V220|G3V220_HUMAN" 3 1002.4435 0.05 42680 7140 2 1002.4442 502.229 Transcription elongation regulator 1 OS=Homo sapiens OX=9606 GN=TCERG1 PE=1 SV=2 8.16 1822.4 - 977578 - - - 0.7332 - 1.294 0.326 - 244.1 1 2 0 0.0007 7 0 0 0 1.79E+07 3.58E+08 - - - 2.2653 0.9375 221125_WJC_METTL3_EV_vs_WT_F04.07143.07143.2 1.82 14-May K.ESGLISTK.K sp|Q9NWT1|PK1IP_HUMAN 1 833.4494 0.44 42683 7143 2 833.448678 417.732 p21-activated protein kinase-interacting protein 1 OS=Homo sapiens OX=9606 GN=PAK1IP1 PE=1 SV=2 6.1 1822.7 - 1.64E+06 - - - -0.9239 - 1.173 0.027 - 103.3 3 2 0 -0.0008 8 0 0 0 1.99E+07 4.47E+07 - - - -0.4917 0.9604 221125_WJC_METTL3_EV_vs_WT_F04.07150.07150.2 0.277 12-Jun K.NYEEIAK[136.11].V sp|P49755|TMEDA_HUMAN 1 873.4323 1.51 42688 7150 2 873.433457 437.7235 Transmembrane emp24 domain-containing protein 10 OS=Homo sapiens OX=9606 GN=TMED10 PE=1 SV=2 4.53 1823.4 - 841507 - - - 1.2697 - 1.327 0.005 - 203.1 1 2 0 0.0011 7 0 0 0 1.74E+08 1.15E+08 - - - -0.026 0.9982 221125_WJC_METTL3_EV_vs_WT_F04.07151.07151.2 0.112 14-Sep R.LEQEQLER.E "sp|Q8N8S7|ENAH_HUMAN,tr|A0A0U1RQP7|A0A0U1RQP7_HUMAN,tr|A0A075B6E5|A0A075B6E5_HUMAN,tr|A0A0U1RRM6|A0A0U1RRM6_HUMAN" 4 1043.5247 0.48 42689 7151 2 1043.525123 522.7696 Protein enabled homolog OS=Homo sapiens OX=9606 GN=ENAH PE=1 SV=2 4.25 1823.5 - 582988 - - - 0.3689 - 1.96 0.113 - 343 1 2 0 0.0004 8 0 0 0 3.58E+07 7.46E+07 - - - 1.9051 0.8185 221125_WJC_METTL3_EV_vs_WT_F04.07155.07155.2 5.79 12-Apr K.NYEEIAK.V sp|P49755|TMEDA_HUMAN 1 865.4181 1.51 42691 7155 2 865.418451 433.7164 Transmembrane emp24 domain-containing protein 10 OS=Homo sapiens OX=9606 GN=TMED10 PE=1 SV=2 4.53 1824 - 1.77E+06 - - - 0.3501 - 0.99 0.006 - 99.1 6 2 0 0.0003 7 0 0 0 1.74E+08 1.15E+08 - - - -1.2942 0.9856 221125_WJC_METTL3_EV_vs_WT_F04.07156.07156.2 0.116 16-Jul R.HSVAVMTVR[166.11].E sp|Q9BRS2|RIOK1_HUMAN 1 1008.5414 0.88 42692 7156 2 1008.537395 505.278 Serine\threonine-protein kinase RIO1 OS=Homo sapiens OX=9606 GN=RIOK1 PE=1 SV=2 9.76 1824.1 - 382910 - - - -3.976 - 1.466 0.248 - 127.7 1 2 0 -0.004 9 0 0 0 8.23E+06 9.37E+06 - - - 1.9782 0.9996 221125_WJC_METTL3_EV_vs_WT_F04.07157.07157.2 0.0136 16-Sep R.QVQPEGPYR[166.11].V "sp|P49327|FAS_HUMAN,tr|A0A0U1RQF0|A0A0U1RQF0_HUMAN" 2 1082.5384 7.47 42693 7157 2 1082.538158 542.2765 Fatty acid synthase OS=Homo sapiens OX=9606 GN=FASN PE=1 SV=3 6 1824.2 - 1.41E+06 - - - -0.2494 - 1.563 0.397 - 285.8 1 2 0 -0.0003 9 0 0 0 3.13E+08 4.20E+07 - - - 3.2652 0.9983 221125_WJC_METTL3_EV_vs_WT_F04.07158.07158.2 0.25 14-Oct R.KGTLTVLK.K "sp|Q9UHB6|LIMA1_HUMAN,tr|F8VVQ7|F8VVQ7_HUMAN,tr|F8VRN8|F8VRN8_HUMAN,tr|F8VTU2|F8VTU2_HUMAN" 4 858.5539 1.13 42694 7158 2 858.553867 430.2842 LIM domain and actin-binding protein 1 OS=Homo sapiens OX=9606 GN=LIMA1 PE=1 SV=1 10 1824.3 - 961280 - - - 0.0151 - 1.849 0.142 - 333.4 1 2 0 0 8 0 0 0 2.26E+07 2.01E+07 - - - 1.9435 0.9991 221125_WJC_METTL3_EV_vs_WT_F04.07159.07159.2 0.164 20-Sep R.VAGALVQNTEK[136.11].G sp|Q9UPN7|PP6R1_HUMAN 1 1136.6281 0.3 42695 7159 2 1136.627403 569.3213 Serine\threonine-protein phosphatase 6 regulatory subunit 1 OS=Homo sapiens OX=9606 GN=PPP6R1 PE=1 SV=5 5.97 1824.4 - 332858 - - - -0.6027 - 1.711 0.275 - 158 1 2 0 -0.0007 11 0 0 0 4.84E+06 1.59E+07 - - - 2.5249 0.9993 221125_WJC_METTL3_EV_vs_WT_F04.07164.07164.2 0.268 16-Aug K.LDGTEINGR.N "sp|Q13247|SRSF6_HUMAN,tr|A0A590UK80|A0A590UK80_HUMAN,tr|A0A590UJK4|A0A590UJK4_HUMAN,tr|A0A590UJP7|A0A590UJP7_HUMAN,tr|A0A590UK01|A0A590UK01_HUMAN" 5 973.4829 1.73 42699 7164 2 973.483175 487.7487 Serine\arginine-rich splicing factor 6 OS=Homo sapiens OX=9606 GN=SRSF6 PE=1 SV=2 4.37 1825 - 689502 - - - 0.3102 - 1.811 0.276 - 146.8 1 2 0 0.0003 9 0 0 0 5.68E+07 3.28E+07 - - - 2.7976 0.9958 221125_WJC_METTL3_EV_vs_WT_F04.07166.07166.2 0.118 14-Sep R.LEQEQLER[166.11].E "sp|Q8N8S7|ENAH_HUMAN,tr|A0A0U1RQP7|A0A0U1RQP7_HUMAN,tr|A0A075B6E5|A0A075B6E5_HUMAN,tr|A0A0U1RRM6|A0A0U1RRM6_HUMAN" 4 1053.533 1.27 42701 7166 2 1053.532747 527.7738 Protein enabled homolog OS=Homo sapiens OX=9606 GN=ENAH PE=1 SV=2 4.25 1825.1 - 919326 - - - -0.2477 - 1.696 0.079 - 356.3 1 2 0 -0.0003 8 0 0 0 2.91E+07 2.30E+07 - - - 1.2177 0.9998 221125_WJC_METTL3_EV_vs_WT_F04.07167.07167.2 0.00195 16-Nov R.VTDALNATR[166.11].A "sp|P10809|CH60_HUMAN,tr|A0A7I2V2X6|A0A7I2V2X6_HUMAN,tr|A0A7I2YQK6|A0A7I2YQK6_HUMAN,tr|A0A7I2V599|A0A7I2V599_HUMAN" 4 969.5119 1.31 42702 7167 2 969.511272 485.7632 "60 kDa heat shock protein, mitochondrial OS=Homo sapiens OX=9606 GN=HSPD1 PE=1 SV=2" 5.81 1825.2 - 903667 - - - -0.6261 - 2.142 0.42 - 432.1 1 2 0 -0.0006 9 0 0 0 6.63E+07 5.07E+07 - - - 4.3467 0.9999 221125_WJC_METTL3_EV_vs_WT_F04.07168.07168.2 5.33E-07 18-Nov R.IADGYEQAAR.V "sp|P48643|TCPE_HUMAN,tr|E9PCA1|E9PCA1_HUMAN,tr|B7ZAR1|B7ZAR1_HUMAN,tr|E7ENZ3|E7ENZ3_HUMAN" 4 1092.52 0.68 42703 7168 2 1092.520351 547.2673 T-complex protein 1 subunit epsilon OS=Homo sapiens OX=9606 GN=CCT5 PE=1 SV=1 4.37 1825.4 - 611192 - - - 0.3332 - 2.322 0.491 - 359.2 1 2 0 0.0004 10 0 0 0 2.02E+09 2.97E+09 - - - 5.0189 0.9997 221125_WJC_METTL3_EV_vs_WT_F04.07173.07173.2 0.00578 18-Oct R.IADGYEQAAR[166.11].V "sp|P48643|TCPE_HUMAN,tr|E9PCA1|E9PCA1_HUMAN,tr|B7ZAR1|B7ZAR1_HUMAN,tr|E7ENZ3|E7ENZ3_HUMAN" 4 1102.5283 0.68 42706 7173 2 1102.527974 552.2714 T-complex protein 1 subunit epsilon OS=Homo sapiens OX=9606 GN=CCT5 PE=1 SV=1 4.37 1826.1 - 3.40E+06 - - - -0.2567 - 1.929 0.359 - 308.7 1 2 0 -0.0003 10 0 0 0 2.02E+09 2.97E+09 - - - 3.5264 0.9996 221125_WJC_METTL3_EV_vs_WT_F04.07174.07174.2 0.000572 16-Aug R.SVLGEADQK.G "sp|P49588|SYAC_HUMAN,tr|A0A6Q8PGR9|A0A6Q8PGR9_HUMAN,tr|A0A6Q8PFY2|A0A6Q8PFY2_HUMAN,tr|A0A6Q8PFK3|A0A6Q8PFK3_HUMAN,tr|H3BPK7|H3BPK7_HUMAN,tr|A0A6Q8PHJ2|A0A6Q8PHJ2_HUMAN,tr|A0A6Q8PGB5|A0A6Q8PGB5_HUMAN,tr|A0A6Q8PGE8|A0A6Q8PGE8_HUMAN,tr|A0A6Q8PF33|A0A6Q8PF33_HUMAN,tr|A0A6Q8PGN5|A0A6Q8PGN5_HUMAN,tr|A0A6Q8PH44|A0A6Q8PH44_HUMAN" 11 945.4767 1.36 42707 7174 2 945.476465 473.7456 "Alanine--tRNA ligase, cytoplasmic OS=Homo sapiens OX=9606 GN=AARS1 PE=1 SV=2" 4.37 1826.1 - 991981 - - - -0.275 - 1.58 0.403 - 189.8 1 2 0 -0.0003 9 0 0 0 2.57E+07 1.89E+07 - - - 3.3408 0.9997 221125_WJC_METTL3_EV_vs_WT_F04.07176.07176.2 3.12E-05 18-Oct K.ILVNDGDASK[136.11].A "sp|Q6W2J9|BCOR_HUMAN,tr|H7BZ37|H7BZ37_HUMAN,tr|H7C2V9|H7C2V9_HUMAN,tr|A0A5F9ZGX7|A0A5F9ZGX7_HUMAN,tr|H7BYY2|H7BYY2_HUMAN,tr|H7C231|H7C231_HUMAN" 6 1038.5437 1.77 42709 7176 2 1038.542927 520.2791 BCL-6 corepressor OS=Homo sapiens OX=9606 GN=BCOR PE=1 SV=1 4.21 1826.4 - 603995 - - - -0.7337 - 2.163 0.351 - 272.4 1 2 0 -0.0008 10 0 0 0 2.19E+08 1.24E+08 - - - 3.7867 0.9976 221125_WJC_METTL3_EV_vs_WT_F04.07177.07177.2 0.000451 20-Aug K.LTVAENEAETK[136.11].L sp|P07814|SYEP_HUMAN 1 1211.6125 0.99 42710 7177 2 1211.616966 606.8135 Bifunctional glutamate\proline--tRNA ligase OS=Homo sapiens OX=9606 GN=EPRS1 PE=1 SV=5 4.25 1826.5 - 206478 - - - 3.6885 - 1.693 0.41 - 189.3 1 2 0 0.0045 11 0 0 0 1.53E+08 1.55E+08 - - - 3.4922 0.9999 221125_WJC_METTL3_EV_vs_WT_F04.07181.07181.2 3.77E-06 20-Nov R.IANSAGYVGDR.F "sp|Q6W2J9|BCOR_HUMAN,tr|H7BZ37|H7BZ37_HUMAN,tr|A1A564|A1A564_HUMAN,tr|H7C2V9|H7C2V9_HUMAN,tr|H7BYY2|H7BYY2_HUMAN,tr|H7C231|H7C231_HUMAN" 6 1121.5465 1.69 42712 7181 2 1121.545719 561.7805 BCL-6 corepressor OS=Homo sapiens OX=9606 GN=BCOR PE=1 SV=1 5.84 1827 - 421004 - - - -0.7285 - 2.331 0.458 - 386.7 1 2 0 -0.0008 11 0 0 0 1.03E+08 6.13E+07 - - - 4.713 0.9991 221125_WJC_METTL3_EV_vs_WT_F04.07182.07182.2 0.0075 18-Aug K.LEQSEAQLGR.G sp|Q92905|CSN5_HUMAN 1 1129.5728 1.17 42713 7182 2 1129.570514 565.7937 COP9 signalosome complex subunit 5 OS=Homo sapiens OX=9606 GN=COPS5 PE=1 SV=4 4.53 1827.1 - 590675 - - - -1.9804 - 1.949 0.318 - 196.9 1 2 0 -0.0022 10 0 0 0 1.40E+07 1.20E+07 - - - 3.2517 0.9999 221125_WJC_METTL3_EV_vs_WT_F04.07183.07183.2 6.78E-06 20-Oct K.LTVAENEAETK.L sp|P07814|SYEP_HUMAN 1 1203.5983 0.99 42714 7183 2 1203.596902 602.8064 Bifunctional glutamate\proline--tRNA ligase OS=Homo sapiens OX=9606 GN=EPRS1 PE=1 SV=5 4.25 1827.3 - 417629 - - - -1.159 - 2.056 0.537 - 315 1 2 0 -0.0014 11 0 0 0 1.53E+08 1.55E+08 - - - 4.9567 0.998 221125_WJC_METTL3_EV_vs_WT_F04.07184.07184.2 0.136 14-Jul K.TEISEMNR[166.11].N sp|P05787|K2C8_HUMAN 1 988.4523 1.89 42715 7184 2 988.451524 495.2334 "Keratin, type II cytoskeletal 8 OS=Homo sapiens OX=9606 GN=KRT8 PE=1 SV=7" 4.53 1827.4 - 371229 - - - -0.8002 - 1.26 0.291 - 206.4 1 2 0 -0.0008 8 0 0 0 1.97E+07 1.04E+07 - - - 1.8871 0.9994 221125_WJC_METTL3_EV_vs_WT_F04.07188.07188.2 0.0395 18-Aug K.ILVNDGDASK.A "sp|Q6W2J9|BCOR_HUMAN,tr|H7BZ37|H7BZ37_HUMAN,tr|H7C2V9|H7C2V9_HUMAN,tr|A0A5F9ZGX7|A0A5F9ZGX7_HUMAN,tr|H7BYY2|H7BYY2_HUMAN,tr|H7C231|H7C231_HUMAN" 6 1030.5295 1.77 42717 7188 2 1030.53104 516.272 BCL-6 corepressor OS=Homo sapiens OX=9606 GN=BCOR PE=1 SV=1 4.21 1827.8 - 2.94E+06 - - - 1.5051 - 1.744 0.372 - 149.1 1 2 0 0.0016 10 0 0 0 2.19E+08 1.24E+08 - - - 3.3406 0.9996 221125_WJC_METTL3_EV_vs_WT_F04.07192.07192.2 0.00492 20-Aug R.ADTQTYQPYNK.D sp|P84090|ERH_HUMAN 1 1327.6044 3.29 42721 7192 2 1327.60297 664.8095 Enhancer of rudimentary homolog OS=Homo sapiens OX=9606 GN=ERH PE=1 SV=1 5.88 1828.3 - 233022 - - - -1.111 - 1.845 0.393 - 170.5 1 2 0 -0.0015 11 0 0 0 7.70E+06 2.34E+06 - - - 3.6001 0.991 221125_WJC_METTL3_EV_vs_WT_F04.07196.07196.2 0.379 12-Jun R.DSEGTWR.K sp|Q14152|EIF3A_HUMAN 1 849.3617 1.22 42723 7196 2 849.360533 425.6881 Eukaryotic translation initiation factor 3 subunit A OS=Homo sapiens OX=9606 GN=EIF3A PE=1 SV=1 4.37 1828.7 - 1.33E+06 - - - -1.3693 - 1.327 0.136 - 240.1 1 2 0 -0.0012 7 0 0 0 3.63E+07 2.97E+07 - - - 0.9416 0.9985 221125_WJC_METTL3_EV_vs_WT_F04.07199.07199.2 0.202 18-Oct R.LIQC[160.03]ENEVGK.L "sp|Q92540|SMG7_HUMAN,tr|E9PD50|E9PD50_HUMAN,tr|B1ALB4|B1ALB4_HUMAN" 3 1188.5809 7.81 42726 7199 2 1188.57806 595.2977 Protein SMG7 OS=Homo sapiens OX=9606 GN=SMG7 PE=1 SV=2 4.53 1829.1 - 523175 - - - -2.3667 - 1.714 0.327 - 150.6 1 2 0 -0.0028 10 0 0 0 2.60E+07 3.32E+06 - - - 2.9594 0.9985 221125_WJC_METTL3_EV_vs_WT_F04.07201.07201.2 0.141 16-Jun R.C[160.03]NLAC[160.03]TPPR.H "sp|P46379|BAG6_HUMAN,tr|A0A7I2V508|A0A7I2V508_HUMAN,tr|A0A0G2JJM1|A0A0G2JJM1_HUMAN,tr|X6REW1|X6REW1_HUMAN,tr|A0A7P0MQS5|A0A7P0MQS5_HUMAN,tr|F6S6P2|F6S6P2_HUMAN,tr|A0A0G2JL47|A0A0G2JL47_HUMAN,tr|A0A024RCR6|A0A024RCR6_HUMAN,tr|A0A0G2JK23|A0A0G2JK23_HUMAN" 9 1087.4903 0.48 42728 7201 2 1087.490852 544.7524 Large proline-rich protein BAG6 OS=Homo sapiens OX=9606 GN=BAG6 PE=1 SV=2 8.07 1829.3 - 189617 - - - 0.5223 - 1.393 0.283 - 77.8 1 2 0 0.0006 9 0 0 0 6.93E+06 1.43E+07 - - - 2.09 0.9986 221125_WJC_METTL3_EV_vs_WT_F04.07205.07205.2 0.122 14-Jul K.FASNVVEK.C "sp|Q8TB72|PUM2_HUMAN,sp|Q14671|PUM1_HUMAN,tr|Q5T1Z8|Q5T1Z8_HUMAN,tr|H0YDK8|H0YDK8_HUMAN,tr|H0YC97|H0YC97_HUMAN,tr|A0A0C4DG68|A0A0C4DG68_HUMAN,tr|H0YEH2|H0YEH2_HUMAN,tr|Q5T1Z4|Q5T1Z4_HUMAN,tr|H0YDC5|H0YDC5_HUMAN,tr|E9PR38|E9PR38_HUMAN" 10 892.4654 1.66 42730 7205 2 892.464362 447.24 Pumilio homolog 2 OS=Homo sapiens OX=9606 GN=PUM2 PE=1 SV=2 6 1829.8 - 5.21E+06 - - - -1.1989 - 1.326 0.33 - 103.3 1 2 0 -0.0011 8 0 0 0 1.17E+08 7.04E+07 - - - 2.329 0.9996 221125_WJC_METTL3_EV_vs_WT_F04.07206.07206.2 0.035 14-Jun K.LNSGVDYR.G sp|P62312|LSM6_HUMAN 1 922.4508 2.38 42731 7206 2 922.451015 462.2327 U6 snRNA-associated Sm-like protein LSm6 OS=Homo sapiens OX=9606 GN=LSM6 PE=1 SV=1 5.84 1829.9 - 1.43E+06 - - - 0.1843 - 1.458 0.419 - 115.1 1 2 0 0.0002 8 0 0 0 3.05E+07 1.28E+07 - - - 3.2729 0.9998 221125_WJC_METTL3_EV_vs_WT_F04.07212.07212.2 0.00176 14-Sep K.TEISEMNR.N sp|P05787|K2C8_HUMAN 1 978.444 1.07 42735 7212 2 978.443204 490.2293 "Keratin, type II cytoskeletal 8 OS=Homo sapiens OX=9606 GN=KRT8 PE=1 SV=7" 4.53 1830.7 - 730220 - - - -0.8595 - 2.029 0.413 - 347.8 1 2 0 -0.0008 8 0 0 0 1.96E+07 1.84E+07 - - - 4.2251 0.9993 221125_WJC_METTL3_EV_vs_WT_F04.07215.07215.2 0.00275 14-Sep K.C[160.03]NESLYGR[166.11].K sp|Q13643|FHL3_HUMAN 1 1007.437 0.86 42738 7215 2 1007.435101 504.7258 Four and a half LIM domains protein 3 OS=Homo sapiens OX=9606 GN=FHL3 PE=1 SV=4 5.99 1831.1 - 533972 - - - -1.885 - 1.813 0.353 - 383.9 1 2 0 -0.0019 8 0 0 0 1.77E+07 2.06E+07 - - - 3.4421 0.9996 221125_WJC_METTL3_EV_vs_WT_F04.07218.07218.2 0.0102 14-Aug R.TSMTEEYR[166.11].V "sp|Q92945|FUBP2_HUMAN,tr|M0R0I5|M0R0I5_HUMAN,tr|M0R0C6|M0R0C6_HUMAN,tr|A0A087WTP3|A0A087WTP3_HUMAN" 4 1025.4363 0.81 42739 7218 2 1025.437338 513.7254 Far upstream element-binding protein 2 OS=Homo sapiens OX=9606 GN=KHSRP PE=1 SV=4 4.53 1831.5 - 1.55E+06 - - - 0.982 - 1.544 0.427 - 310.2 1 2 0 0.001 8 0 0 0 2.68E+07 3.33E+07 - - - 3.5046 0.999 221125_WJC_METTL3_EV_vs_WT_F04.07228.07228.2 3.20E-06 16-Sep K.EGETVEPYK.V sp|Q08211|DHX9_HUMAN 1 1050.487 0.85 42747 7228 2 1050.483055 526.2508 ATP-dependent RNA helicase A OS=Homo sapiens OX=9606 GN=DHX9 PE=1 SV=4 4.25 1832.6 - 607429 - - - -3.7135 - 1.927 0.502 - 415.3 1 2 0 -0.0039 9 0 0 0 8.26E+07 9.71E+07 - - - 4.6453 0.9996 221125_WJC_METTL3_EV_vs_WT_F04.07232.07232.2 0.0147 12-Jun K.DDEDSFR.R sp|Q9H0D6|XRN2_HUMAN 1 882.3355 1.11 42748 7232 2 882.334483 442.175 5'-3' exoribonuclease 2 OS=Homo sapiens OX=9606 GN=XRN2 PE=1 SV=1 3.84 1833.2 - 789064 - - - -1.198 - 1.295 0.491 - 152.9 1 2 0 -0.0011 7 0 0 0 2.72E+07 2.45E+07 - - - 3.4863 0.9996 221125_WJC_METTL3_EV_vs_WT_F04.07233.07233.2 0.0127 16-Aug R.LEC[160.03]VEPNC[160.03]R.S "sp|P83881|RL36A_HUMAN,sp|Q969Q0|RL36L_HUMAN,tr|H0Y5B4|H0Y5B4_HUMAN,tr|J3KQN4|J3KQN4_HUMAN,tr|H7BZ11|H7BZ11_HUMAN" 5 1175.5063 0.91 42749 7233 2 1175.503891 588.7604 60S ribosomal protein L36a OS=Homo sapiens OX=9606 GN=RPL36A PE=1 SV=2 4.53 1833.3 - 535103 - - - -2.0731 - 1.853 0.454 - 304.4 1 2 0 -0.0024 9 0 0 0 7.67E+07 8.47E+07 - - - 4.1779 0.9129 221125_WJC_METTL3_EV_vs_WT_F04.07234.07234.2 0.0322 16-Sep A.SAITPSVSR.T "sp|P13647|K2C5_HUMAN,tr|F8VV57|F8VV57_HUMAN,tr|F8VU69|F8VU69_HUMAN" 3 916.4978 4.69 42750 7234 2 916.498697 459.2562 "Keratin, type II cytoskeletal 5 OS=Homo sapiens OX=9606 GN=KRT5 PE=1 SV=3" 9.47 1833.3 - 1.72E+06 - - - 0.9842 - 1.872 0.183 - 215.3 1 1 0 0.0009 9 0 0 0 5.40E+07 1.15E+07 - - - 2.2063 0.9978 221125_WJC_METTL3_EV_vs_WT_F04.07235.07235.2 1.99E-05 14-Jul K.C[160.03]NESLYGR.K sp|Q13643|FHL3_HUMAN 1 997.4287 0.82 42751 7235 2 997.426008 499.7216 Four and a half LIM domains protein 3 OS=Homo sapiens OX=9606 GN=FHL3 PE=1 SV=4 5.99 1833.5 - 617747 - - - -2.729 - 1.634 0.313 - 241.9 1 2 0 -0.0027 8 0 0 0 1.67E+07 2.04E+07 - - - 2.8329 0.9877 221125_WJC_METTL3_EV_vs_WT_F04.07240.07240.2 0.73 14-Jun K.QAIQASIK[136.11].E "sp|Q86SF2|GALT7_HUMAN,tr|E9PBY3|E9PBY3_HUMAN" 2 865.5113 1.7 42754 7240 2 865.509796 433.7629 N-acetylgalactosaminyltransferase 7 OS=Homo sapiens OX=9606 GN=GALNT7 PE=1 SV=1 8.75 1834.1 - 2.81E+06 - - - -1.6996 - 1.354 0.159 - 107.1 4 2 0 -0.0015 8 0 0 0 1.37E+08 8.02E+07 - - - 0.86 0.9971 221125_WJC_METTL3_EV_vs_WT_F04.07242.07242.2 0.222 14-Jul R.TVVSVLKK.S sp|Q10471|GALT2_HUMAN 1 872.5695 1.75 42756 7242 2 872.568175 437.292 Polypeptide N-acetylgalactosaminyltransferase 2 OS=Homo sapiens OX=9606 GN=GALNT2 PE=1 SV=1 10 1834.2 - 1.36E+06 - - - -1.5231 - 1.353 0.258 - 131.5 1 2 0 -0.0013 8 0 0 0 5.27E+07 3.02E+07 - - - 1.858 0.9996 221125_WJC_METTL3_EV_vs_WT_F04.07245.07245.2 1.13 16-Sep R.LEC[160.03]VEPNC[160.03]R[166.11].S "sp|P83881|RL36A_HUMAN,sp|Q969Q0|RL36L_HUMAN,tr|H0Y5B4|H0Y5B4_HUMAN,tr|J3KQN4|J3KQN4_HUMAN,tr|H7BZ11|H7BZ11_HUMAN" 5 1185.5146 0.91 42757 7245 2 1185.513209 593.7646 60S ribosomal protein L36a OS=Homo sapiens OX=9606 GN=RPL36A PE=1 SV=2 4.53 1834.6 - 1.08E+06 - - - -1.1716 - 1.953 0.36 - 392.3 1 2 0 -0.0014 9 0 0 0 7.67E+07 8.47E+07 - - - 3.636 0.9591 221125_WJC_METTL3_EV_vs_WT_F04.07250.07250.2 1.25 12-May R.NGYDLAK.A sp|O94776|MTA2_HUMAN 1 779.3814 1.19 42762 7250 2 779.381451 390.698 Metastasis-associated protein MTA2 OS=Homo sapiens OX=9606 GN=MTA2 PE=1 SV=1 5.83 1835.2 - 506375 - - - 0.1065 - 0.965 0.133 - 87 3 2 0 0.0001 7 0 0 0 1.23E+07 1.03E+07 - - - -0.3027 0.9995 221125_WJC_METTL3_EV_vs_WT_F04.07253.07253.2 0.0137 16-Aug K.STMQELNSR.L sp|P35527|K1C9_HUMAN 1 1064.4921 185.73 42763 7253 2 1064.491347 533.2533 "Keratin, type I cytoskeletal 9 OS=Homo sapiens OX=9606 GN=KRT9 PE=1 SV=3" 5.72 1835.6 - 7.05E+06 - - - -0.6679 - 1.698 0.336 - 249 1 2 0 -0.0007 9 0 0 0 7.07E+08 3.81E+06 - - - 3.0542 0.8761 221125_WJC_METTL3_EV_vs_WT_F04.07256.07256.2 1.76 12-May R.NGYDLAK[136.11].A sp|O94776|MTA2_HUMAN 1 787.3956 1.19 42766 7256 2 787.394126 394.7051 Metastasis-associated protein MTA2 OS=Homo sapiens OX=9606 GN=MTA2 PE=1 SV=1 5.83 1835.8 - 543694 - - - -1.8314 - 0.968 0.075 - 85.3 2 2 0 -0.0014 7 0 0 0 1.23E+07 1.03E+07 - - - -0.643 0.9997 221125_WJC_METTL3_EV_vs_WT_F04.07259.07259.2 0.117 12-Jun K.DDEDSFR[166.11].R sp|Q9H0D6|XRN2_HUMAN 1 892.3438 1.11 42767 7259 2 892.343764 447.1792 5'-3' exoribonuclease 2 OS=Homo sapiens OX=9606 GN=XRN2 PE=1 SV=1 3.84 1836.2 - 1.01E+06 - - - -0.0515 - 1.384 0.469 - 165.5 1 2 0 0 7 0 0 0 2.72E+07 2.45E+07 - - - 3.5347 0.9985 221125_WJC_METTL3_EV_vs_WT_F04.07262.07262.2 0.00217 16-Oct R.GGPGGELPR[166.11].G "sp|Q04637|IF4G1_HUMAN,tr|C9J2Z7|C9J2Z7_HUMAN,tr|E7EUU4|E7EUU4_HUMAN,tr|E9PGM1|E9PGM1_HUMAN,tr|C9J6B6|C9J6B6_HUMAN,tr|E7EX73|E7EX73_HUMAN,tr|C9K073|C9K073_HUMAN,tr|A0A7I2Y1C3|A0A7I2Y1C3_HUMAN,tr|C9JF13|C9JF13_HUMAN" 9 848.438 1.11 42770 7262 2 848.438031 425.2263 Eukaryotic translation initiation factor 4 gamma 1 OS=Homo sapiens OX=9606 GN=EIF4G1 PE=1 SV=4 6 1836.5 - 877741 - - - 0.053 - 1.836 0.164 - 283.4 1 2 0 0 9 0 0 0 1.05E+08 9.42E+07 - - - 2.0101 0.7883 221125_WJC_METTL3_EV_vs_WT_F04.07266.07266.2 0.0871 14-Jul E.ELQVTAGR.H "sp|P48668|K2C6C_HUMAN,sp|O95678|K2C75_HUMAN,sp|P02538|K2C6A_HUMAN" 3 872.4716 21.72 42772 7266 2 872.472211 437.2431 "Keratin, type II cytoskeletal 6C OS=Homo sapiens OX=9606 GN=KRT6C PE=1 SV=3" 6.1 1837 - 612378 - - - 0.7232 - 1.32 0.193 - 206.2 1 1 0 0.0006 8 0 0 0 1.71E+07 7.86E+05 - - - 1.3036 0.9962 221125_WJC_METTL3_EV_vs_WT_F04.07268.07268.2 0.0239 14-Jul K.AAFQSQYK[136.11].S "sp|Q86XP3|DDX42_HUMAN,tr|A0A0A0MSJ0|A0A0A0MSJ0_HUMAN" 2 949.4749 1.32 42773 7268 2 949.472976 475.7447 ATP-dependent RNA helicase DDX42 OS=Homo sapiens OX=9606 GN=DDX42 PE=1 SV=1 8.63 1837.2 - 1.49E+06 - - - -2.0064 - 1.335 0.268 - 163.3 1 2 0 -0.0019 8 0 0 0 5.22E+07 3.95E+07 - - - 1.8913 0.9993 221125_WJC_METTL3_EV_vs_WT_F04.07276.07276.2 0.00693 14-Jul K.DSLYAQGR[166.11].R sp|Q969Q0|RL36L_HUMAN 1 918.4435 1.26 42778 7276 2 918.444266 460.229 60S ribosomal protein L36a-like OS=Homo sapiens OX=9606 GN=RPL36AL PE=1 SV=3 5.84 1838.2 - 900153 - - - 0.8721 - 1.534 0.351 - 179.2 1 2 0 0.0008 8 0 0 0 2.62E+07 2.08E+07 - - - 2.9237 0.9994 221125_WJC_METTL3_EV_vs_WT_F04.07277.07277.2 0.00727 18-Aug R.VQPNEAVYTK[136.11].M sp|P11413|G6PD_HUMAN 1 1155.6015 0.33 42779 7277 2 1155.601695 578.808 Glucose-6-phosphate 1-dehydrogenase OS=Homo sapiens OX=9606 GN=G6PD PE=1 SV=4 5.97 1838.3 - 375094 - - - 0.135 - 1.599 0.343 - 256.1 1 2 0 0.0002 10 0 0 0 7.23E+06 2.19E+07 - - - 2.8845 1 221125_WJC_METTL3_EV_vs_WT_F04.07278.07278.3 4.90E-06 14/40 R.LVSGLEAK[136.11]PDR[166.11].S sp|O15119|TBX3_HUMAN 1 1201.6786 0.93 42780 7278 3 1201.678631 401.5668 T-box transcription factor TBX3 OS=Homo sapiens OX=9606 GN=TBX3 PE=1 SV=4 6.07 1838.4 - 680783 - - - 0.0616 - 2.376 0.452 - 202.6 1 2 0 0.0001 11 0 0 0 3.38E+07 3.64E+07 - - - 6.0378 0.8142 221125_WJC_METTL3_EV_vs_WT_F04.07279.07279.2 0.00296 20-Jun A.AAAAYSDGYGR[166.11].V "sp|O43251|RFOX2_HUMAN,tr|B0QYV1|B0QYV1_HUMAN,tr|A0A0G2JRD1|A0A0G2JRD1_HUMAN,tr|A0A0G2JRA5|A0A0G2JRA5_HUMAN,tr|S4R3K7|S4R3K7_HUMAN" 5 1110.497 1.17 42781 7279 2 1110.493923 556.2558 RNA binding protein fox-1 homolog 2 OS=Homo sapiens OX=9606 GN=RBFOX2 PE=1 SV=3 5.88 1838.5 - 135425 - - - -2.7321 - 1.435 0.315 - 71.5 1 1 0 -0.003 11 0 0 0 2.38E+07 2.03E+07 - - - 2.3437 0.9962 221125_WJC_METTL3_EV_vs_WT_F04.07282.07282.2 0.092 16-Jul R.TQAPAVATT.- "sp|P15880|RS2_HUMAN,tr|E9PQD7|E9PQD7_HUMAN,tr|H0YEN5|H0YEN5_HUMAN" 3 858.4447 - 42782 7282 2 858.445063 430.2296 40S ribosomal protein S2 OS=Homo sapiens OX=9606 GN=RPS2 PE=1 SV=2 5.19 1838.9 - 5.57E+06 - - - 0.4264 - 1.268 0.221 - 173.4 1 2 0 0.0004 9 0 0 0 - - - - - 1.3601 0.9998 221125_WJC_METTL3_EV_vs_WT_F04.07283.07283.2 0.00903 18-Oct K.IFAQDGEGQR.L "sp|O75369|FLNB_HUMAN,tr|E7EN95|E7EN95_HUMAN,tr|A0A804HK76|A0A804HK76_HUMAN,tr|A0A804HL72|A0A804HL72_HUMAN" 4 1119.5309 1.8 42783 7283 2 1119.530077 560.7727 Filamin-B OS=Homo sapiens OX=9606 GN=FLNB PE=1 SV=2 4.37 1839.1 - 576435 - - - -0.7226 - 1.993 0.41 - 379.9 1 2 0 -0.0008 10 0 0 0 8.96E+07 4.98E+07 - - - 3.994 0.9996 221125_WJC_METTL3_EV_vs_WT_F04.07284.07284.2 0.000262 18-Sep K.IFAQDGEGQR[166.11].L "sp|O75369|FLNB_HUMAN,tr|E7EN95|E7EN95_HUMAN,tr|A0A804HK76|A0A804HK76_HUMAN,tr|A0A804HL72|A0A804HL72_HUMAN" 4 1129.5392 0.85 42784 7284 2 1129.536458 565.7769 Filamin-B OS=Homo sapiens OX=9606 GN=FLNB PE=1 SV=2 4.37 1839.2 - 525110 - - - -2.3886 - 1.901 0.507 - 303.6 1 2 0 -0.0027 10 0 0 0 2.42E+07 2.84E+07 - - - 4.5779 0.9995 221125_WJC_METTL3_EV_vs_WT_F04.07289.07289.2 0.00638 16-Sep K.GPSSVEDIK.A "sp|P06748|NPM_HUMAN,tr|E5RI98|E5RI98_HUMAN,tr|A0A7I2YQC0|A0A7I2YQC0_HUMAN,tr|A0A7I2V5J8|A0A7I2V5J8_HUMAN,tr|A0A7I2V5S2|A0A7I2V5S2_HUMAN" 5 930.4658 0.87 42787 7289 2 930.465744 466.2402 Nucleophosmin OS=Homo sapiens OX=9606 GN=NPM1 PE=1 SV=2 4.37 1839.7 - 1.42E+07 - - - -0.0881 - 1.566 0.369 - 208.4 1 2 0 -0.0001 9 0 0 0 3.15E+09 3.62E+09 - - - 3.064 0.9582 221125_WJC_METTL3_EV_vs_WT_F04.07292.07292.2 0.0119 16-Aug S.R[166.11]SHEDGSER.D sp|Q86W56|PARG_HUMAN 1 1081.4776 - 42789 7292 2 1081.47895 541.7461 Poly(ADP-ribose) glycohydrolase OS=Homo sapiens OX=9606 GN=PARG PE=1 SV=1 5.45 1840.1 - 2.27E+06 - - - 1.2307 - 1.667 0.342 - 194.4 1 1 0 0.0013 9 0 0 0 - - - - - 3.045 0.9999 221125_WJC_METTL3_EV_vs_WT_F04.07294.07294.3 0.000897 13/40 R.LVSGLEAKPDR.S sp|O15119|TBX3_HUMAN 1 1183.6561 0.93 42790 7294 3 1183.656658 395.5593 T-box transcription factor TBX3 OS=Homo sapiens OX=9606 GN=TBX3 PE=1 SV=4 6.07 1840.3 - 922282 - - - 0.4824 - 2.452 0.429 - 212.5 1 2 0 0.0006 11 0 0 0 3.38E+07 3.64E+07 - - - 5.8707 0.9998 221125_WJC_METTL3_EV_vs_WT_F04.07295.07295.2 0.000118 16-Oct K.TAETGYIQR.R "sp|P24928|RPB1_HUMAN,tr|A0A6Q8PGB0|A0A6Q8PGB0_HUMAN" 2 1037.5142 1.09 42791 7295 2 1037.515577 519.7644 DNA-directed RNA polymerase II subunit RPB1 OS=Homo sapiens OX=9606 GN=POLR2A PE=1 SV=2 5.66 1840.4 - 485371 - - - 1.3523 - 1.945 0.477 - 421.4 1 2 0 0.0014 9 0 0 0 3.27E+07 2.99E+07 - - - 4.4883 0.9998 221125_WJC_METTL3_EV_vs_WT_F04.07308.07308.2 0.00214 18-Oct R.LSVAAQEAAR[166.11].L sp|Q15149|PLEC_HUMAN 1 1024.5541 1.44 42798 7308 2 1024.552994 513.2843 Plectin OS=Homo sapiens OX=9606 GN=PLEC PE=1 SV=3 6 1842 - 351518 - - - -1.058 - 2.107 0.426 - 352.5 1 2 0 -0.0011 10 0 0 0 1.83E+07 1.27E+07 - - - 4.2674 0.9872 221125_WJC_METTL3_EV_vs_WT_F04.07309.07309.2 0.0295 18-Aug R.VQPNEAVYTK.M sp|P11413|G6PD_HUMAN 1 1147.5873 0.33 42799 7309 2 1147.592289 574.8009 Glucose-6-phosphate 1-dehydrogenase OS=Homo sapiens OX=9606 GN=G6PD PE=1 SV=4 5.97 1842.1 - 290407 - - - 4.3134 - 1.594 0.266 - 247 1 2 0 0.005 10 0 0 0 7.23E+06 2.19E+07 - - - 2.3056 0.9983 221125_WJC_METTL3_EV_vs_WT_F04.07312.07312.2 0.111 14-Jul K.SLESINSR[166.11].L "sp|P62888|RL30_HUMAN,tr|E5RJH3|E5RJH3_HUMAN,tr|E5RI99|E5RI99_HUMAN,tr|A0A0C4DH44|A0A0C4DH44_HUMAN" 4 914.4697 1.1 42800 7312 2 914.469499 458.2421 60S ribosomal protein L30 OS=Homo sapiens OX=9606 GN=RPL30 PE=1 SV=2 5.72 1842.5 - 1.71E+07 - - - -0.1979 - 1.414 0.25 - 162.6 1 2 0 -0.0002 8 0 0 0 8.15E+08 7.40E+08 - - - 1.9322 0.9988 221125_WJC_METTL3_EV_vs_WT_F04.07315.07315.2 0.00011 18-Nov K.QPVLSQTEAR[166.11].D sp|P28070|PSB4_HUMAN 1 1137.6018 1.6 42803 7315 2 1137.597395 569.8082 Proteasome subunit beta type-4 OS=Homo sapiens OX=9606 GN=PSMB4 PE=1 SV=4 6 1842.8 - 529153 - - - -3.8344 - 1.954 0.495 - 524.6 1 2 0 -0.0044 10 0 0 0 2.51E+08 1.57E+08 - - - 4.5655 0.997 221125_WJC_METTL3_EV_vs_WT_F04.07317.07317.2 0.0418 12-Jul R.C[160.03]LISC[160.03]SK.K "sp|Q969X6|UTP4_HUMAN,tr|H3BSH7|H3BSH7_HUMAN,tr|A0A0J9YWK2|A0A0J9YWK2_HUMAN,tr|A0A0J9YXV4|A0A0J9YXV4_HUMAN,tr|A0A0J9YWM9|A0A0J9YWM9_HUMAN" 5 866.399 0.82 42805 7317 2 866.398242 434.2068 U3 small nucleolar RNA-associated protein 4 homolog OS=Homo sapiens OX=9606 GN=UTP4 PE=1 SV=1 8.06 1843.1 - 311852 - - - -0.8864 - 1.329 0.222 - 206.3 1 2 0 -0.0008 7 0 0 0 1.34E+07 1.62E+07 - - - 1.5817 0.9919 221125_WJC_METTL3_EV_vs_WT_F04.07319.07319.2 0.0167 16-Jul K.GPSSVEDIK[136.11].A "sp|P06748|NPM_HUMAN,tr|E5RI98|E5RI98_HUMAN,tr|A0A7I2YQC0|A0A7I2YQC0_HUMAN,tr|A0A7I2V5J8|A0A7I2V5J8_HUMAN,tr|A0A7I2V5S2|A0A7I2V5S2_HUMAN" 5 938.48 0.87 42806 7319 2 938.475516 470.2473 Nucleophosmin OS=Homo sapiens OX=9606 GN=NPM1 PE=1 SV=2 4.37 1843.3 - 1.12E+08 - - - -4.8056 - 1.585 0.363 - 146.1 1 2 0 -0.0045 9 0 0 0 3.15E+09 3.62E+09 - - - 3.0532 0.9988 221125_WJC_METTL3_EV_vs_WT_F04.07321.07321.2 0.245 14-Aug K.SLESINSR.L "sp|P62888|RL30_HUMAN,tr|E5RJH3|E5RJH3_HUMAN,tr|E5RI99|E5RI99_HUMAN,tr|A0A0C4DH44|A0A0C4DH44_HUMAN" 4 904.4614 1.1 42807 7321 2 904.460679 453.238 60S ribosomal protein L30 OS=Homo sapiens OX=9606 GN=RPL30 PE=1 SV=2 5.72 1843.5 - 2.28E+07 - - - -0.8082 - 1.445 0.29 - 208.5 1 2 0 -0.0007 8 0 0 0 8.15E+08 7.40E+08 - - - 2.2929 0.9891 221125_WJC_METTL3_EV_vs_WT_F04.07325.07325.2 0.98 16-Sep R.EYEAALNSK[136.11].D "sp|P20700|LMNB1_HUMAN,tr|A0A0D9SFY5|A0A0D9SFY5_HUMAN,tr|E9PBF6|E9PBF6_HUMAN,tr|A0A0D9SFE5|A0A0D9SFE5_HUMAN" 4 1031.5015 1.16 42811 7325 2 1031.499466 516.758 Lamin-B1 OS=Homo sapiens OX=9606 GN=LMNB1 PE=1 SV=2 4.53 1843.9 - 506306 - - - -1.9622 - 1.128 0.228 - 210.5 1 2 0 -0.002 9 0 0 0 9.08E+07 7.82E+07 - - - 1.0728 0.9996 221125_WJC_METTL3_EV_vs_WT_F04.07330.07330.2 0.002 16-Oct K.TAALVLHGR[166.11].K "sp|Q9NRY5|F1142_HUMAN,tr|E7ESJ7|E7ESJ7_HUMAN" 2 946.5588 1.31 42814 7330 2 946.557488 474.2867 Protein FAM114A2 OS=Homo sapiens OX=9606 GN=FAM114A2 PE=1 SV=4 9.44 1844.4 - 4.00E+06 - - - -1.3533 - 1.831 0.384 - 280.1 1 2 0 -0.0013 9 0 0 0 4.11E+07 3.13E+07 - - - 3.6267 0.9977 221125_WJC_METTL3_EV_vs_WT_F04.07331.07331.2 0.0302 16-Sep R.QVSIEEGER[166.11].K "sp|P20340|RAB6A_HUMAN,sp|Q53S08|RAB6D_HUMAN" 2 1055.5123 1.01 42815 7331 2 1055.508885 528.7634 Ras-related protein Rab-6A OS=Homo sapiens OX=9606 GN=RAB6A PE=1 SV=3 4.25 1844.4 - 5.45E+06 - - - -3.2098 - 1.748 0.34 - 374.4 1 2 0 -0.0034 9 0 0 0 1.36E+08 1.35E+08 - - - 3.1669 0.9445 221125_WJC_METTL3_EV_vs_WT_F04.07333.07333.2 0.0664 14-Jun R.EGSPANWK.R sp|O96019|ACL6A_HUMAN 1 887.4137 1.2 42817 7333 2 887.41051 444.7141 Actin-like protein 6A OS=Homo sapiens OX=9606 GN=ACTL6A PE=1 SV=1 6.1 1844.6 - 942527 - - - -3.6296 - 1.074 0.203 - 115.4 1 2 0 -0.0032 8 0 0 0 2.38E+07 1.99E+07 - - - 0.7547 0.9009 221125_WJC_METTL3_EV_vs_WT_F04.07334.07334.2 6.56 14-Jun K.NIIYHAVK[136.11].D "sp|Q7LBC6|KDM3B_HUMAN,sp|Q15652|JHD2C_HUMAN,tr|A0A1W2PNZ9|A0A1W2PNZ9_HUMAN" 3 964.5586 2.57 42818 7334 2 964.556384 483.2866 Lysine-specific demethylase 3B OS=Homo sapiens OX=9606 GN=KDM3B PE=1 SV=2 8.6 1844.7 - 459216 - - - -2.2466 - 1.162 0.027 - 109.2 1 2 0 -0.0022 8 0 0 0 2.61E+07 1.02E+07 - - - -0.3074 0.9997 221125_WJC_METTL3_EV_vs_WT_F04.07337.07337.2 2.28E-05 16-Sep R.QVSIEEGER.K "sp|P20340|RAB6A_HUMAN,sp|Q53S08|RAB6D_HUMAN" 2 1045.504 1.01 42819 7337 2 1045.502243 523.7593 Ras-related protein Rab-6A OS=Homo sapiens OX=9606 GN=RAB6A PE=1 SV=3 4.25 1845.1 - 6.43E+06 - - - -1.6834 - 1.769 0.478 - 388.8 1 2 0 -0.0018 9 0 0 0 1.36E+08 1.35E+08 - - - 4.2212 0.9995 221125_WJC_METTL3_EV_vs_WT_F04.07339.07339.2 0.00721 16-Oct K.LLENEQVQK[136.11].L "sp|Q8IWJ2|GCC2_HUMAN,tr|B8ZZW2|B8ZZW2_HUMAN" 2 1107.6015 3.49 42821 7339 2 1107.599049 554.808 GRIP and coiled-coil domain-containing protein 2 OS=Homo sapiens OX=9606 GN=GCC2 PE=1 SV=4 4.53 1845.3 - 761498 - - - -2.2481 - 2.032 0.399 - 285.1 1 2 0 -0.0025 9 0 0 0 4.57E+07 1.31E+07 - - - 4.0385 0.9984 221125_WJC_METTL3_EV_vs_WT_F04.07344.07344.2 0.186 14-Aug R.ISSSSFSR.V "sp|P05787|K2C8_HUMAN,tr|F8VUG2|F8VUG2_HUMAN,tr|Q8IWY7|Q8IWY7_HUMAN,tr|F8W1U3|F8W1U3_HUMAN,tr|F8VQY3|F8VQY3_HUMAN" 5 869.4243 1.82 42824 7344 2 869.423143 435.7194 "Keratin, type II cytoskeletal 8 OS=Homo sapiens OX=9606 GN=KRT8 PE=1 SV=7" 9.75 1845.9 - 2.39E+06 - - - -1.3262 - 1.564 0.252 - 157.8 1 2 0 -0.0012 8 0 0 0 1.41E+08 7.75E+07 - - - 2.2508 0.9999 221125_WJC_METTL3_EV_vs_WT_F04.07345.07345.2 0.000124 13/18 R.ITGNPVVTNR[166.11].L "sp|Q9HCE1|MOV10_HUMAN,tr|Q5JR04|Q5JR04_HUMAN" 2 1079.5963 1.01 42825 7345 2 1079.596995 540.8054 Helicase MOV-10 OS=Homo sapiens OX=9606 GN=MOV10 PE=1 SV=2 9.75 1846 - 859072 - - - 0.6651 - 2.445 0.437 - 630.4 1 2 0 0.0007 10 0 0 0 4.40E+07 4.37E+07 - - - 4.764 0.9885 221125_WJC_METTL3_EV_vs_WT_F04.07346.07346.2 0.0047 22-Jul K.YLASGSGDTTVR[166.11].F sp|Q9NVX2|NLE1_HUMAN 1 1235.6022 0.6 42826 7346 2 1235.595689 618.8084 Notchless protein homolog 1 OS=Homo sapiens OX=9606 GN=NLE1 PE=1 SV=4 5.84 1846.2 - 293590 - - - -5.2298 - 1.365 0.425 - 115.9 1 2 0 -0.0065 12 0 0 0 5.65E+06 9.49E+06 - - - 2.9967 0.998 221125_WJC_METTL3_EV_vs_WT_F04.07347.07347.2 0.848 18-Jun R.IVEQDTMPPK[136.11].G "sp|O00571|DDX3X_HUMAN,sp|O15523|DDX3Y_HUMAN,tr|A0A2R8YFR4|A0A2R8YFR4_HUMAN,tr|A0A2R8YCW1|A0A2R8YCW1_HUMAN,tr|A0A2R8YDH3|A0A2R8YDH3_HUMAN,tr|A0A2R8YDT5|A0A2R8YDT5_HUMAN,tr|A0A2R8Y645|A0A2R8Y645_HUMAN,tr|A0A2R8YF78|A0A2R8YF78_HUMAN,tr|A0A0D9SFB3|A0A0D9SFB3_HUMAN,tr|A0A2R8YFS5|A0A2R8YFS5_HUMAN,tr|A0A0D9SF53|A0A0D9SF53_HUMAN,tr|A0A2R8Y5G6|A0A2R8Y5G6_HUMAN,tr|A0A2R8Y7T2|A0A2R8Y7T2_HUMAN,tr|A0A0D9SG12|A0A0D9SG12_HUMAN,tr|F6S8Q4|F6S8Q4_HUMAN,tr|A0A2U3TZJ9|A0A2U3TZJ9_HUMAN,tr|A0A2R8Y4A4|A0A2R8Y4A4_HUMAN" 17 1164.594 0.8 42827 7347 2 1164.592411 583.3043 ATP-dependent RNA helicase DDX3X OS=Homo sapiens OX=9606 GN=DDX3X PE=1 SV=3 4.37 1846.3 - 287052 - - - -1.373 - 1.312 0.309 - 112.2 1 2 0 -0.0016 10 0 0 0 8.54E+06 1.07E+07 - - - 2.0808 0.9284 221125_WJC_METTL3_EV_vs_WT_F04.07348.07348.2 0.527 20-Jun K.VLTQPSQSAVR[166.11].G sp|Q9UP83|COG5_HUMAN 1 1194.6596 1.64 42828 7348 2 1194.654754 598.3371 Conserved oligomeric Golgi complex subunit 5 OS=Homo sapiens OX=9606 GN=COG5 PE=1 SV=3 9.72 1846.4 - 219583 - - - -4.0614 - 1.163 0.181 - 125 1 2 0 -0.0049 11 0 0 0 9.62E+06 5.88E+06 - - - 0.7848 0.9974 221125_WJC_METTL3_EV_vs_WT_F04.07351.07351.2 0.187 14-Jul K.EIQDLQSR.Q "sp|Q9H4A3|WNK1_HUMAN,tr|F5GWT4|F5GWT4_HUMAN,tr|B7Z613|B7Z613_HUMAN,tr|A0A6Q8PFM0|A0A6Q8PFM0_HUMAN" 4 987.4985 2.03 42829 7351 2 987.497147 494.7565 Serine\threonine-protein kinase WNK1 OS=Homo sapiens OX=9606 GN=WNK1 PE=1 SV=2 4.37 1846.8 - 2.37E+06 - - - -1.3934 - 1.384 0.253 - 208.4 1 2 0 -0.0014 8 0 0 0 2.04E+08 1.01E+08 - - - 1.8893 0.9873 221125_WJC_METTL3_EV_vs_WT_F04.07357.07357.2 0.063 16-Sep R.QGNPVAPIK.T sp|Q10471|GALT2_HUMAN 1 922.5236 1.67 42833 7357 2 922.523878 462.2691 Polypeptide N-acetylgalactosaminyltransferase 2 OS=Homo sapiens OX=9606 GN=GALNT2 PE=1 SV=1 8.75 1847.6 - 4.06E+06 - - - 0.284 - 1.485 0.04 - 419.6 1 2 0 0.0003 9 0 0 0 4.18E+08 2.50E+08 - - - 0.4803 0.9945 221125_WJC_METTL3_EV_vs_WT_F04.07359.07359.2 0.42 14-Jun R.FNTGPVGK[136.11].G "sp|Q6P2Q9|PRP8_HUMAN,tr|I3L0J9|I3L0J9_HUMAN" 2 826.4429 0.27 42835 7359 2 826.442022 414.2287 Pre-mRNA-processing-splicing factor 8 OS=Homo sapiens OX=9606 GN=PRPF8 PE=1 SV=2 8.75 1847.7 - 1.23E+06 - - - -1.0055 - 1.39 0.182 - 90.2 3 2 0 -0.0008 8 0 0 0 2.75E+07 1.02E+08 - - - 1.165 0.999 221125_WJC_METTL3_EV_vs_WT_F04.07360.07360.2 0.00805 14-Jul R.FNTGPVGK.G "sp|Q6P2Q9|PRP8_HUMAN,tr|I3L0J9|I3L0J9_HUMAN" 2 818.4287 0.28 42836 7360 2 818.428806 410.2216 Pre-mRNA-processing-splicing factor 8 OS=Homo sapiens OX=9606 GN=PRPF8 PE=1 SV=2 8.75 1847.8 - 1.04E+06 - - - 0.1869 - 1.49 0.296 - 123.7 1 2 0 0.0002 8 0 0 0 2.70E+07 9.60E+07 - - - 2.4299 0.9923 221125_WJC_METTL3_EV_vs_WT_F04.07361.07361.2 0.041 12-Jul R.NVYQNYR[166.11].Q sp|Q8IYI6|EXOC8_HUMAN 1 965.4594 1.49 42837 7361 2 965.455519 483.737 Exocyst complex component 8 OS=Homo sapiens OX=9606 GN=EXOC8 PE=1 SV=2 8.59 1847.9 - 917029 - - - -4.0706 - 1.283 0.372 - 221 1 2 0 -0.0039 7 0 0 0 9.85E+07 6.63E+07 - - - 2.577 0.9962 221125_WJC_METTL3_EV_vs_WT_F04.07362.07362.2 0.298 12-Jul K.SLNISTK.V "sp|O15504|NUP42_HUMAN,sp|P51843|NR0B1_HUMAN,tr|A6NNU8|A6NNU8_HUMAN,tr|C9JYA1|C9JYA1_HUMAN" 4 761.4283 2.34 42838 7362 2 761.427972 381.7214 Nucleoporin NUP42 OS=Homo sapiens OX=9606 GN=NUP42 PE=1 SV=1 8.47 1848 - 892467 - - - -0.4557 - 1.453 0.148 - 156.2 1 2 0 -0.0003 7 0 0 0 4.91E+07 2.10E+07 - - - 1.3179 0.9994 221125_WJC_METTL3_EV_vs_WT_F04.07363.07363.2 0.000513 20-Oct K.ELEAASAPEER[166.11].T "sp|O43432|IF4G3_HUMAN,tr|A0A804HJV5|A0A804HJV5_HUMAN,tr|A0A0U1RQK7|A0A0U1RQK7_HUMAN,tr|A0A0A0MSA7|A0A0A0MSA7_HUMAN" 4 1210.5705 0.13 42839 7363 2 1210.57264 606.2925 Eukaryotic translation initiation factor 4 gamma 3 OS=Homo sapiens OX=9606 GN=EIF4G3 PE=1 SV=2 4.09 1848.1 - 425508 - - - 1.7545 - 1.632 0.43 - 195.9 1 2 0 0.0021 11 0 0 0 2.78E+06 2.17E+07 - - - 3.5414 0.999 221125_WJC_METTL3_EV_vs_WT_F04.07369.07369.2 0.0114 20-Jul K.VLTQPSQSAVR.G sp|Q9UP83|COG5_HUMAN 1 1184.6513 1.64 42843 7369 2 1184.651124 593.3329 Conserved oligomeric Golgi complex subunit 5 OS=Homo sapiens OX=9606 GN=COG5 PE=1 SV=3 9.72 1848.9 - 259708 - - - -0.179 - 1.437 0.317 - 78.9 1 2 0 -0.0002 11 0 0 0 9.62E+06 5.88E+06 - - - 2.3631 0.9902 221125_WJC_METTL3_EV_vs_WT_F04.07370.07370.2 0.113 14-Jul K.EIQDLQSR[166.11].Q "sp|Q9H4A3|WNK1_HUMAN,tr|F5GWT4|F5GWT4_HUMAN,tr|B7Z613|B7Z613_HUMAN,tr|A0A6Q8PFM0|A0A6Q8PFM0_HUMAN" 4 997.5068 2.02 42844 7370 2 997.507343 499.7607 Serine\threonine-protein kinase WNK1 OS=Homo sapiens OX=9606 GN=WNK1 PE=1 SV=2 4.37 1849 - 3.24E+06 - - - 0.5514 - 1.327 0.109 - 260.7 1 2 0 0.0006 8 0 0 0 2.04E+08 1.01E+08 - - - 0.6992 0.9997 221125_WJC_METTL3_EV_vs_WT_F04.07372.07372.2 0.00178 20-Jun K.ELEAASAPEER.T "sp|O43432|IF4G3_HUMAN,tr|A0A804HJV5|A0A804HJV5_HUMAN,tr|A0A0U1RQK7|A0A0U1RQK7_HUMAN,tr|A0A0A0MSA7|A0A0A0MSA7_HUMAN" 4 1200.5622 0.12 42846 7372 2 1200.562488 601.2884 Eukaryotic translation initiation factor 4 gamma 3 OS=Homo sapiens OX=9606 GN=EIF4G3 PE=1 SV=2 4.09 1849.2 - 184780 - - - 0.2016 - 1.614 0.456 - 101.8 1 2 0 0.0002 11 0 0 0 1.35E+06 1.16E+07 - - - 3.704 0.9662 221125_WJC_METTL3_EV_vs_WT_F04.07374.07374.2 1.22 14-Jul R.QALASISK[136.11].S "sp|Q96PV6|LENG8_HUMAN,tr|A0A0G2JPW6|A0A0G2JPW6_HUMAN,tr|E7EWC7|E7EWC7_HUMAN,tr|C9JMY0|C9JMY0_HUMAN,tr|C9J1N5|C9J1N5_HUMAN,tr|A0A0G2JN70|A0A0G2JN70_HUMAN,tr|A0A087WUE4|A0A087WUE4_HUMAN,tr|B0VJY8|B0VJY8_HUMAN" 8 824.4847 0.8 42847 7374 2 824.48428 413.2496 Leukocyte receptor cluster member 8 OS=Homo sapiens OX=9606 GN=LENG8 PE=1 SV=3 8.75 1849.4 - 781043 - - - -0.5312 - 1.264 0.012 - 104.6 1 2 0 -0.0004 8 0 0 0 5.05E+07 6.34E+07 - - - -0.1639 0.9997 221125_WJC_METTL3_EV_vs_WT_F04.07380.07380.2 0.000117 18-Aug R.AMNGESLDGR.Q sp|P98179|RBM3_HUMAN 1 1048.4608 1.04 42850 7380 2 1048.45983 525.2377 RNA-binding protein 3 OS=Homo sapiens OX=9606 GN=RBM3 PE=1 SV=1 4.37 1850.2 - 1.34E+06 - - - -0.8851 - 1.923 0.405 - 216.1 1 2 0 -0.0009 10 0 0 0 2.54E+08 2.43E+08 - - - 3.8572 0.9579 221125_WJC_METTL3_EV_vs_WT_F04.07383.07383.2 3.56 14-Jun K.HVSPLIGR[166.11].F "sp|Q9H9B4|SFXN1_HUMAN,tr|D6RFI0|D6RFI0_HUMAN" 2 887.5217 0.84 42853 7383 2 887.52106 444.7681 Sideroflexin-1 OS=Homo sapiens OX=9606 GN=SFXN1 PE=1 SV=4 9.76 1850.5 - 645967 - - - -0.6715 - 1.152 0.07 - 103.6 4 2 0 -0.0006 8 0 0 0 5.11E+07 6.10E+07 - - - -0.2844 0.9787 221125_WJC_METTL3_EV_vs_WT_F04.07386.07386.2 0.0169 18-Jul R.ATVLESEGTR.E "sp|Q9UJZ1|STML2_HUMAN,tr|A0A087WYB4|A0A087WYB4_HUMAN,tr|F2Z2I8|F2Z2I8_HUMAN" 3 1061.5353 1.34 42854 7386 2 1061.540592 531.7749 "Stomatin-like protein 2, mitochondrial OS=Homo sapiens OX=9606 GN=STOML2 PE=1 SV=1" 4.53 1850.9 - 3.75E+06 - - - 4.9824 - 1.79 0.237 - 204.6 2 2 0 0.0053 10 0 0 0 2.43E+08 1.80E+08 - - - 2.2805 0.9656 221125_WJC_METTL3_EV_vs_WT_F04.07387.07387.2 0.38 12-Jun R.ELLPVK[136.11]K[136.11].F sp|Q08211|DHX9_HUMAN 1 841.5608 0.79 42855 7387 2 841.560342 421.7877 ATP-dependent RNA helicase A OS=Homo sapiens OX=9606 GN=DHX9 PE=1 SV=4 8.69 1851.1 - 878663 - - - -0.5323 - 0.935 0.135 - 92.6 1 2 0 -0.0004 7 0 0 0 2.32E+07 2.95E+07 - - - -0.175 0.9998 221125_WJC_METTL3_EV_vs_WT_F04.07395.07395.2 2.06E-05 18-Sep R.AMNGESLDGR[166.11].Q sp|P98179|RBM3_HUMAN 1 1058.469 1.04 42859 7395 2 1058.46854 530.2418 RNA-binding protein 3 OS=Homo sapiens OX=9606 GN=RBM3 PE=1 SV=1 4.37 1851.9 - 3.96E+06 - - - -0.461 - 1.835 0.444 - 292.4 1 2 0 -0.0005 10 0 0 0 2.54E+08 2.43E+08 - - - 4.0147 0.9986 221125_WJC_METTL3_EV_vs_WT_F04.07396.07396.2 0.0176 14-Sep K.AIQALNGR.W "sp|Q9UHX1|PUF60_HUMAN,tr|A0A0J9YYL3|A0A0J9YYL3_HUMAN,tr|A0A0J9YXX5|A0A0J9YXX5_HUMAN,tr|A0A0J9YXJ8|A0A0J9YXJ8_HUMAN,tr|A0A0J9YVP6|A0A0J9YVP6_HUMAN" 5 841.477 1.34 42860 7396 2 841.477086 421.7458 Poly(U)-binding-splicing factor PUF60 OS=Homo sapiens OX=9606 GN=PUF60 PE=1 SV=1 9.79 1852 - 844874 - - - 0.1022 - 1.514 0.239 - 238.7 1 2 0 0.0001 8 0 0 0 3.10E+07 2.31E+07 - - - 2.0571 0.9994 221125_WJC_METTL3_EV_vs_WT_F04.07397.07397.2 0.0414 18-Nov R.ITGNPVVTNR.L "sp|Q9HCE1|MOV10_HUMAN,tr|Q5JR04|Q5JR04_HUMAN" 2 1069.588 1.01 42861 7397 2 1069.590037 535.8013 Helicase MOV-10 OS=Homo sapiens OX=9606 GN=MOV10 PE=1 SV=2 9.75 1852.1 - 1.54E+06 - - - 1.8979 - 2.184 0.321 - 421.4 1 2 0 0.002 10 0 0 0 4.40E+07 4.37E+07 - - - 3.5917 0.992 221125_WJC_METTL3_EV_vs_WT_F04.07401.07401.2 0.422 16-Aug R.QGNPVAPIK[136.11].T sp|Q10471|GALT2_HUMAN 1 930.5378 1.69 42863 7401 2 930.538605 466.2762 Polypeptide N-acetylgalactosaminyltransferase 2 OS=Homo sapiens OX=9606 GN=GALNT2 PE=1 SV=1 8.75 1852.6 - 1.45E+07 - - - 0.8479 - 1.178 0.19 - 158.8 1 2 0 0.0008 9 0 0 0 4.10E+08 2.42E+08 - - - 0.918 0.9981 221125_WJC_METTL3_EV_vs_WT_F04.07402.07402.2 0.184 14-Jun R.ETGVDLTK[136.11].D "sp|P38646|GRP75_HUMAN,tr|H0Y8K0|H0Y8K0_HUMAN,tr|A0A7I2V2G2|A0A7I2V2G2_HUMAN,tr|A0A7I2V3F7|A0A7I2V3F7_HUMAN,tr|A0A7I2YQB2|A0A7I2YQB2_HUMAN,tr|D6RCD7|D6RCD7_HUMAN" 6 869.4586 0.43 42864 7402 2 869.459277 435.7366 "Stress-70 protein, mitochondrial OS=Homo sapiens OX=9606 GN=HSPA9 PE=1 SV=2" 4.37 1852.7 - 5.71E+06 - - - 0.8212 - 1.562 0.216 - 143.1 1 2 0 0.0007 8 0 0 0 8.47E+08 1.98E+09 - - - 1.9812 0.9966 221125_WJC_METTL3_EV_vs_WT_F04.07403.07403.2 0.0391 14-Jul R.ETGVDLTK.D "sp|P38646|GRP75_HUMAN,tr|H0Y8K0|H0Y8K0_HUMAN,tr|A0A7I2V2G2|A0A7I2V2G2_HUMAN,tr|A0A7I2V3F7|A0A7I2V3F7_HUMAN,tr|A0A7I2YQB2|A0A7I2YQB2_HUMAN,tr|D6RCD7|D6RCD7_HUMAN" 6 861.4444 0.43 42865 7403 2 861.444426 431.7295 "Stress-70 protein, mitochondrial OS=Homo sapiens OX=9606 GN=HSPA9 PE=1 SV=2" 4.37 1852.7 - 1.89E+06 - - - 0.0731 - 1.279 0.216 - 185 1 2 0 0.0001 8 0 0 0 8.47E+08 1.98E+09 - - - 1.3785 0.9305 221125_WJC_METTL3_EV_vs_WT_F04.07405.07405.2 0.15 12-Jun A.GEVFIHK[136.11].D "sp|Q15233|NONO_HUMAN,tr|A0A7I2V535|A0A7I2V535_HUMAN,tr|A0A7I2V4N2|A0A7I2V4N2_HUMAN,tr|A0A7I2V4K9|A0A7I2V4K9_HUMAN,tr|A0A7I2V464|A0A7I2V464_HUMAN,tr|A0A7P0MRW0|A0A7P0MRW0_HUMAN,tr|H7C367|H7C367_HUMAN,tr|C9IZL7|C9IZL7_HUMAN,tr|A0A7I2YQK8|A0A7I2YQK8_HUMAN,tr|A0A7I2V4J2|A0A7I2V4J2_HUMAN,tr|A0A7I2V5Y7|A0A7I2V5Y7_HUMAN,tr|C9JYS8|C9JYS8_HUMAN" 12 836.4636 0.78 42866 7405 2 836.463799 419.2391 Non-POU domain-containing octamer-binding protein OS=Homo sapiens OX=9606 GN=NONO PE=1 SV=4 6.75 1852.9 - 3.49E+06 - - - 0.2523 - 1.288 0.32 - 208.3 1 1 0 0.0002 7 0 0 0 9.71E+07 1.24E+08 - - - 2.2064 0.9992 221125_WJC_METTL3_EV_vs_WT_F04.07415.07415.2 0.00142 16-Jun R.EPYMC[160.03]AQC[160.03]K.T sp|Q86YP4|P66A_HUMAN 1 1185.4617 1.39 42873 7415 2 1185.461549 593.7381 Transcriptional repressor p66-alpha OS=Homo sapiens OX=9606 GN=GATAD2A PE=1 SV=1 6.08 1854 - 146288 - - - -0.1156 - 1.066 0.452 - 61.9 1 2 0 -0.0001 9 0 0 0 1.27E+07 9.12E+06 - - - 2.5643 0.9969 221125_WJC_METTL3_EV_vs_WT_F04.07426.07426.2 0.00612 16-Oct R.IQNPSAYAK[136.11].R "sp|Q92615|LAR4B_HUMAN,tr|H0Y4V9|H0Y4V9_HUMAN" 2 998.5276 1.33 42878 7426 2 998.530875 500.2711 La-related protein 4B OS=Homo sapiens OX=9606 GN=LARP4B PE=1 SV=3 8.59 1855.5 - 1.81E+06 - - - 3.2348 - 1.865 0.279 - 228.5 1 2 0 0.0032 9 0 0 0 6.03E+08 4.52E+08 - - - 2.9038 0.9822 221125_WJC_METTL3_EV_vs_WT_F04.07435.07435.2 0.0395 14-Jul R.EVVEDINK.L sp|Q9UL15|BAG5_HUMAN 1 944.4815 1.34 42883 7435 2 944.480746 473.248 BAG family molecular chaperone regulator 5 OS=Homo sapiens OX=9606 GN=BAG5 PE=1 SV=1 4.14 1856.5 - 1.29E+06 - - - -0.7729 - 1.466 0.014 - 210.1 1 2 0 -0.0007 8 0 0 0 3.05E+07 2.27E+07 - - - 0.2979 0.933 221125_WJC_METTL3_EV_vs_WT_F04.07438.07438.2 0.0216 12-May R.AQHIVPC[160.03].T "sp|P15927|RFA2_HUMAN,tr|Q5TEJ7|Q5TEJ7_HUMAN" 2 823.4011 - 42886 7438 2 823.400594 412.7078 Replication protein A 32 kDa subunit OS=Homo sapiens OX=9606 GN=RPA2 PE=1 SV=1 6.78 1856.8 - 803517 - - - -0.5635 - 1.264 0.334 - 175.3 1 1 0 -0.0005 7 0 0 0 - - - - - 2.2501 0.9998 221125_WJC_METTL3_EV_vs_WT_F04.07439.07439.2 4.55E-05 20-Oct R.IVAVTGAEAQK.A "sp|P49588|SYAC_HUMAN,tr|A0A6Q8PGR9|A0A6Q8PGR9_HUMAN,tr|A0A6Q8PFY2|A0A6Q8PFY2_HUMAN,tr|A0A6Q8PFK3|A0A6Q8PFK3_HUMAN,tr|H3BPK7|H3BPK7_HUMAN,tr|A0A6Q8PGB5|A0A6Q8PGB5_HUMAN,tr|A0A6Q8PGE8|A0A6Q8PGE8_HUMAN,tr|A0A6Q8PF33|A0A6Q8PF33_HUMAN,tr|A0A6Q8PGN5|A0A6Q8PGN5_HUMAN" 9 1085.6081 1.53 42887 7439 2 1085.607712 543.8113 "Alanine--tRNA ligase, cytoplasmic OS=Homo sapiens OX=9606 GN=AARS1 PE=1 SV=2" 6 1857 - 655307 - - - -0.3335 - 1.856 0.428 - 291.4 1 2 0 -0.0004 11 0 0 0 1.95E+07 1.27E+07 - - - 3.8751 0.9926 221125_WJC_METTL3_EV_vs_WT_F04.07441.07441.2 0.131 16-Jul K.IIPSPDDSK[136.11].F "sp|Q9Y2H2|SAC2_HUMAN,tr|A0A3B3ISI3|A0A3B3ISI3_HUMAN,tr|A0A3B3ITL0|A0A3B3ITL0_HUMAN,tr|A0A3B3ITR9|A0A3B3ITR9_HUMAN,tr|A0A3B3ISJ5|A0A3B3ISJ5_HUMAN" 5 978.5113 3.05 42889 7441 2 978.513453 490.2629 Phosphatidylinositide phosphatase SAC2 OS=Homo sapiens OX=9606 GN=INPP5F PE=1 SV=3 4.21 1857.2 - 165075 - - - 2.1727 - 1.333 0.222 - 92.7 1 2 0 0.0021 9 0 0 0 3.18E+07 1.04E+07 - - - 1.5116 0.9997 221125_WJC_METTL3_EV_vs_WT_F04.07443.07443.2 0.00246 18-Oct K.QPVLSQTEAR.D sp|P28070|PSB4_HUMAN 1 1127.5935 1.6 42890 7443 2 1127.594151 564.804 Proteasome subunit beta type-4 OS=Homo sapiens OX=9606 GN=PSMB4 PE=1 SV=4 6 1857.4 - 1.19E+06 - - - 0.5889 - 1.535 0.454 - 381 1 2 0 0.0007 10 0 0 0 2.51E+08 1.57E+08 - - - 3.5902 0.996 221125_WJC_METTL3_EV_vs_WT_F04.07453.07453.2 0.171 18-Aug K.ATIISEQQAK[136.11].S "sp|P51692|STA5B_HUMAN,sp|P42229|STA5A_HUMAN,tr|A0A7I2YQY3|A0A7I2YQY3_HUMAN,tr|K7EIF9|K7EIF9_HUMAN,tr|K7EK35|K7EK35_HUMAN,tr|A0A7I2V380|A0A7I2V380_HUMAN,tr|A0A7I2YQF1|A0A7I2YQF1_HUMAN" 7 1095.6015 0.01 42896 7453 2 1095.600828 548.808 Signal transducer and activator of transcription 5B OS=Homo sapiens OX=9606 GN=STAT5B PE=1 SV=2 6.05 1858.6 - 761892 - - - -0.649 - 1.695 0.108 - 142.2 1 2 0 -0.0007 10 0 0 0 2.94E+05 2.47E+07 - - - 1.3114 0.9829 221125_WJC_METTL3_EV_vs_WT_F04.07455.07455.2 0.151 12-May R.EYTTIC[160.03]R[166.11].L "sp|O75569|PRKRA_HUMAN,tr|B4DJC7|B4DJC7_HUMAN,tr|A0A7I2V3J2|A0A7I2V3J2_HUMAN,tr|A0A7I2V2I8|A0A7I2V2I8_HUMAN,tr|A0A7I2V5H3|A0A7I2V5H3_HUMAN,tr|A0A7I2YQ87|A0A7I2YQ87_HUMAN" 6 951.4359 1.2 42897 7455 2 951.433821 476.7252 Interferon-inducible double-stranded RNA-dependent protein kinase activator A OS=Homo sapiens OX=9606 GN=PRKRA PE=1 SV=1 6.09 1858.9 - 930158 - - - -2.224 - 1.143 0.192 - 129.8 1 2 0 -0.0021 7 0 0 0 2.65E+07 2.21E+07 - - - 0.8819 0.9994 221125_WJC_METTL3_EV_vs_WT_F04.07457.07457.2 0.00973 18-Aug R.EMQDLGGGER.M sp|Q02413|DSG1_HUMAN 1 1090.4713 5.44 42898 7457 2 1090.471 546.2429 Desmoglein-1 OS=Homo sapiens OX=9606 GN=DSG1 PE=1 SV=2 4.14 1859.1 - 1.40E+06 - - - -0.2953 - 1.419 0.385 - 237.6 1 2 0 -0.0003 10 0 0 0 6.32E+07 1.16E+07 - - - 2.8613 0.9995 221125_WJC_METTL3_EV_vs_WT_F04.07458.07458.2 0.02 16-Sep K.LTELSGNPR.K "sp|Q13888|TF2H2_HUMAN,sp|Q6P1K8|T2H2L_HUMAN,tr|D6RJD3|D6RJD3_HUMAN,tr|D6RID8|D6RID8_HUMAN,tr|R4GMS9|R4GMS9_HUMAN" 5 985.5193 0.57 42899 7458 2 985.519146 493.7669 General transcription factor IIH subunit 2 OS=Homo sapiens OX=9606 GN=GTF2H2 PE=1 SV=1 6 1859.2 - 317430 - - - -0.1147 - 1.874 0.298 - 220.6 1 2 0 -0.0001 9 0 0 0 1.68E+07 2.94E+07 - - - 3.059 0.9996 221125_WJC_METTL3_EV_vs_WT_F04.07460.07460.2 0.00519 12-Jul K.FDSEYER.M "sp|P43243|MATR3_HUMAN,tr|A8MXP9|A8MXP9_HUMAN,tr|D6R991|D6R991_HUMAN,tr|A0A0R4J2E8|A0A0R4J2E8_HUMAN,tr|H0Y8T4|H0Y8T4_HUMAN,tr|D6REM6|D6REM6_HUMAN" 6 944.3876 1.33 42901 7460 2 944.388334 473.2011 Matrin-3 OS=Homo sapiens OX=9606 GN=MATR3 PE=1 SV=2 4.14 1859.3 - 1.19E+06 - - - 0.8026 - 1.524 0.415 - 157.3 1 2 0 0.0008 7 0 0 0 2.32E+09 1.74E+09 - - - 3.441 0.9997 221125_WJC_METTL3_EV_vs_WT_F04.07461.07461.2 0.000182 16-Aug R.EPYMC[160.03]AQC[160.03]K[136.11].T sp|Q86YP4|P66A_HUMAN 1 1193.4759 1.39 42902 7461 2 1193.476549 597.7452 Transcriptional repressor p66-alpha OS=Homo sapiens OX=9606 GN=GATAD2A PE=1 SV=1 6.08 1859.4 - 347357 - - - 0.5555 - 1.368 0.511 - 190 1 2 0 0.0007 9 0 0 0 1.27E+07 9.12E+06 - - - 3.7216 0.9991 221125_WJC_METTL3_EV_vs_WT_F04.07467.07467.2 0.185 12-Oct K.R[166.11]LDSAFR[166.11].C sp|Q9BYJ9|YTHD1_HUMAN 1 883.4779 3.28 42905 7467 2 883.47722 442.7462 YTH domain-containing family protein 1 OS=Homo sapiens OX=9606 GN=YTHDF1 PE=1 SV=1 9.6 1860.2 - 1.49E+06 - - - -0.7584 - 1.802 0.222 - 368.5 1 2 0 -0.0007 7 0 0 0 1.10E+08 3.36E+07 - - - 2.5464 0.9929 221125_WJC_METTL3_EV_vs_WT_F04.07472.07472.2 2.15 12-Jun R.EALEYQR.Q "sp|Q8TAQ2|SMRC2_HUMAN,tr|F8VXC8|F8VXC8_HUMAN" 2 907.4399 4.07 42907 7472 2 907.439558 454.7272 SWI\SNF complex subunit SMARCC2 OS=Homo sapiens OX=9606 GN=SMARCC2 PE=1 SV=1 4.53 1860.9 - 1.25E+06 - - - -0.4276 - 1.346 0.12 - 164.3 1 2 0 -0.0004 7 0 0 0 9.53E+07 2.34E+07 - - - 0.8687 1 221125_WJC_METTL3_EV_vs_WT_F04.07473.07473.3 9.39E-05 Nov-36 R.LTNSMMMHGR.N "sp|P46782|RS5_HUMAN,tr|M0R0F0|M0R0F0_HUMAN,tr|M0R0R2|M0R0R2_HUMAN" 3 1176.5202 0.93 42908 7473 3 1176.519931 393.1807 40S ribosomal protein S5 OS=Homo sapiens OX=9606 GN=RPS5 PE=1 SV=4 9.76 1861 - 1.40E+06 - - - -0.232 - 2.167 0.504 - 157.9 1 2 0 -0.0003 10 0 0 0 5.01E+08 5.40E+08 - - - 6.4175 0.9974 221125_WJC_METTL3_EV_vs_WT_F04.07474.07474.2 0.208 14-Aug R.R[166.11]AC[160.03]YGVLR[166.11].F "sp|P23396|RS3_HUMAN,tr|H0YEU2|H0YEU2_HUMAN,tr|E9PL09|E9PL09_HUMAN" 3 1013.5344 3.58 42909 7474 2 1013.53558 507.7745 40S ribosomal protein S3 OS=Homo sapiens OX=9606 GN=RPS3 PE=1 SV=2 9.5 1861.1 - 469255 - - - 1.2047 - 1.509 0.219 - 144.9 1 2 0 0.0012 8 0 0 0 5.03E+07 1.40E+07 - - - 1.8991 0.9998 221125_WJC_METTL3_EV_vs_WT_F04.07478.07478.2 3.05E-06 20-Oct K.TTYGGAAAAVR[166.11].Q sp|P49790|NU153_HUMAN 1 1046.5384 1.75 42910 7478 2 1046.539494 524.2765 Nuclear pore complex protein Nup153 OS=Homo sapiens OX=9606 GN=NUP153 PE=1 SV=2 8.41 1861.7 - 4.00E+06 - - - 1.0186 - 2.017 0.502 - 329.1 1 2 0 0.0011 11 0 0 0 3.35E+08 1.92E+08 - - - 4.6465 0.9949 221125_WJC_METTL3_EV_vs_WT_F04.07480.07480.2 3.53 12-Jun R.EALEYQR[166.11].Q "sp|Q8TAQ2|SMRC2_HUMAN,tr|F8VXC8|F8VXC8_HUMAN" 2 917.4482 3.92 42911 7480 2 917.44837 459.7314 SWI\SNF complex subunit SMARCC2 OS=Homo sapiens OX=9606 GN=SMARCC2 PE=1 SV=1 4.53 1861.9 - 876851 - - - 0.1679 - 1.392 0.136 - 162.2 1 2 0 0.0002 7 0 0 0 9.11E+07 2.32E+07 - - - 1.0934 0.9999 221125_WJC_METTL3_EV_vs_WT_F04.07482.07482.3 0.00149 Oct-36 R.LTNSMMMHGR[166.11].N "sp|P46782|RS5_HUMAN,tr|M0R0F0|M0R0F0_HUMAN,tr|M0R0R2|M0R0R2_HUMAN" 3 1186.5285 0.93 42912 7482 3 1186.528567 396.5168 40S ribosomal protein S5 OS=Homo sapiens OX=9606 GN=RPS5 PE=1 SV=4 9.76 1862.1 - 5.22E+06 - - - 0.0784 - 1.911 0.481 - 129.9 1 2 0 0.0001 10 0 0 0 5.02E+08 5.40E+08 - - - 5.794 0.9207 221125_WJC_METTL3_EV_vs_WT_F04.07484.07484.2 0.222 12-Aug K.DALVLHK.V "sp|Q86U86|PB1_HUMAN,tr|H0Y5B5|H0Y5B5_HUMAN,tr|E7EVG2|E7EVG2_HUMAN" 3 794.465 1.3 42914 7484 2 794.467437 398.2398 Protein polybromo-1 OS=Homo sapiens OX=9606 GN=PBRM1 PE=1 SV=1 6.74 1862.2 - 3.38E+06 - - - 3.0196 - 1.442 0.003 - 316.2 1 2 0 0.0024 7 0 0 0 8.39E+07 6.46E+07 - - - 0.2222 0.9999 221125_WJC_METTL3_EV_vs_WT_F04.07489.07489.2 7.97E-07 20-Oct K.TTYGGAAAAVR.Q sp|P49790|NU153_HUMAN 1 1036.5302 1.63 42917 7489 2 1036.531023 519.2724 Nuclear pore complex protein Nup153 OS=Homo sapiens OX=9606 GN=NUP153 PE=1 SV=2 8.41 1862.9 - 7.46E+06 - - - 0.8345 - 2.239 0.536 - 364.1 1 2 0 0.0009 11 0 0 0 3.13E+08 1.92E+08 - - - 5.1801 0.9999 221125_WJC_METTL3_EV_vs_WT_F04.07495.07495.2 6.37E-07 18-Aug R.LTNSMMMHGR.N "sp|P46782|RS5_HUMAN,tr|M0R0F0|M0R0F0_HUMAN,tr|M0R0R2|M0R0R2_HUMAN" 3 1176.5202 1 42921 7495 2 1176.520297 589.2674 40S ribosomal protein S5 OS=Homo sapiens OX=9606 GN=RPS5 PE=1 SV=4 9.76 1863.7 - 705966 - - - 0.079 - 2.112 0.601 - 271.7 1 2 0 0.0001 10 0 0 0 5.09E+07 5.08E+07 - - - 5.5668 0.9992 221125_WJC_METTL3_EV_vs_WT_F04.07499.07499.2 0.0375 18-Sep K.LLEVEHPAAK[136.11].V "sp|P17987|TCPA_HUMAN,tr|F5H726|F5H726_HUMAN,tr|F5H136|F5H136_HUMAN,tr|F5GZI8|F5GZI8_HUMAN,tr|E7ERF2|E7ERF2_HUMAN,tr|F5H676|F5H676_HUMAN" 6 1113.6274 0.49 42923 7499 2 1113.628274 557.821 T-complex protein 1 subunit alpha OS=Homo sapiens OX=9606 GN=TCP1 PE=1 SV=1 5.4 1864.1 - 200288 - - - 0.8216 - 1.82 0.277 - 186.6 1 2 0 0.0009 10 0 0 0 1.69E+08 3.45E+08 - - - 2.7582 0.9991 221125_WJC_METTL3_EV_vs_WT_F04.07502.07502.2 0.0267 14-Jul K.LIHTLDDR.T "sp|Q9BXP5|SRRT_HUMAN,tr|H7C3A1|H7C3A1_HUMAN" 2 981.5243 3.08 42925 7502 2 981.524077 491.7694 Serrate RNA effector molecule homolog OS=Homo sapiens OX=9606 GN=SRRT PE=1 SV=1 5.21 1864.4 - 646144 - - - -0.272 - 1.535 0.284 - 173.6 1 2 0 -0.0003 8 0 0 0 2.38E+07 7.72E+06 - - - 2.431 0.9955 221125_WJC_METTL3_EV_vs_WT_F04.07503.07503.2 0.129 16-Sep R.EVAAPDVGR[166.11].M "sp|Q14254|FLOT2_HUMAN,tr|E7EMK3|E7EMK3_HUMAN,tr|K7EKW9|K7EKW9_HUMAN,tr|J3QLD9|J3QLD9_HUMAN" 4 922.4748 1.62 42926 7503 2 922.476664 462.2447 Flotillin-2 OS=Homo sapiens OX=9606 GN=FLOT2 PE=1 SV=2 4.37 1864.5 - 1.20E+06 - - - 2.0586 - 1.533 0.213 - 421.7 1 2 0 0.0019 9 0 0 0 9.09E+07 5.60E+07 - - - 1.8496 1 221125_WJC_METTL3_EV_vs_WT_F04.07507.07507.2 9.63E-07 18-Nov R.LTNSMMMHGR[166.11].N "sp|P46782|RS5_HUMAN,tr|M0R0F0|M0R0F0_HUMAN,tr|M0R0R2|M0R0R2_HUMAN" 3 1186.5285 1 42929 7507 2 1186.526385 594.2715 40S ribosomal protein S5 OS=Homo sapiens OX=9606 GN=RPS5 PE=1 SV=4 9.76 1864.9 - 1.67E+06 - - - -1.7606 - 2.277 0.629 - 577.3 1 2 0 -0.0021 10 0 0 0 5.08E+07 5.08E+07 - - - 5.983 0.9995 221125_WJC_METTL3_EV_vs_WT_F04.07509.07509.2 0.0108 16-Aug R.EVAAPDVGR.M "sp|Q14254|FLOT2_HUMAN,tr|E7EMK3|E7EMK3_HUMAN,tr|K7EKW9|K7EKW9_HUMAN,tr|J3QLD9|J3QLD9_HUMAN" 4 912.4665 1.6 42930 7509 2 912.465441 457.2405 Flotillin-2 OS=Homo sapiens OX=9606 GN=FLOT2 PE=1 SV=2 4.37 1865.1 - 1.82E+06 - - - -1.1551 - 1.554 0.398 - 304.1 1 2 0 -0.0011 9 0 0 0 9.53E+07 5.96E+07 - - - 3.2556 0.9885 221125_WJC_METTL3_EV_vs_WT_F04.07511.07511.2 1.52 14-Jul K.QQEIVVSR[166.11].G "sp|Q15393|SF3B3_HUMAN,tr|I3L4G7|I3L4G7_HUMAN" 2 967.5326 1.12 42932 7511 2 967.532278 484.7736 Splicing factor 3B subunit 3 OS=Homo sapiens OX=9606 GN=SF3B3 PE=1 SV=4 6 1865.3 - 750898 - - - -0.3473 - 1.437 0.053 - 268.7 1 2 0 -0.0003 8 0 0 0 2.74E+08 2.45E+08 - - - 0.5258 0.9959 221125_WJC_METTL3_EV_vs_WT_F04.07512.07512.2 0.0152 12-Jun K.DC[160.03]EGLPR.E sp|Q9H0D6|XRN2_HUMAN 1 845.3702 1.15 42933 7512 2 845.370819 423.6924 5'-3' exoribonuclease 2 OS=Homo sapiens OX=9606 GN=XRN2 PE=1 SV=1 4.37 1865.3 - 958319 - - - 0.789 - 1.422 0.167 - 199.5 1 2 0 0.0007 7 0 0 0 2.03E+08 1.76E+08 - - - 1.3898 1 221125_WJC_METTL3_EV_vs_WT_F04.07514.07514.2 2.71E-07 24-Dec K.VAEDEAEAAAAAK.F "sp|P08195|4F2_HUMAN,tr|F5H867|F5H867_HUMAN,tr|A0A7P0TAN7|A0A7P0TAN7_HUMAN,tr|J3KPF3|J3KPF3_HUMAN,tr|F5H0E2|F5H0E2_HUMAN,tr|H0YH36|H0YH36_HUMAN,tr|A0A7P0TAT7|A0A7P0TAT7_HUMAN,tr|H0YFS2|H0YFS2_HUMAN,tr|A0A7P0T8U7|A0A7P0T8U7_HUMAN,tr|A0A7P0T9F7|A0A7P0T9F7_HUMAN,tr|A0A7P0TBF8|A0A7P0TBF8_HUMAN,tr|A0A7P0T8F1|A0A7P0T8F1_HUMAN,tr|A0A7P0Z4A0|A0A7P0Z4A0_HUMAN,tr|F5GZS6|F5GZS6_HUMAN,tr|A0A7P0Z4P5|A0A7P0Z4P5_HUMAN,tr|A0A7P0T853|A0A7P0T853_HUMAN,tr|A0A7P0TAS6|A0A7P0TAS6_HUMAN" 17 1244.5885 1.44 42935 7514 2 1244.591194 623.3015 4F2 cell-surface antigen heavy chain OS=Homo sapiens OX=9606 GN=SLC3A2 PE=1 SV=3 4 1865.6 - 207345 - - - 2.1959 - 2.421 0.6 - 459.4 1 2 0 0.0027 13 0 0 0 8.27E+07 5.76E+07 - - - 5.741 0.9882 221125_WJC_METTL3_EV_vs_WT_F04.07519.07519.2 0.283 14-Jul K.EVINGNIK.T "sp|O75821|EIF3G_HUMAN,tr|K7ER90|K7ER90_HUMAN,tr|K7EL20|K7EL20_HUMAN,tr|K7ENA8|K7ENA8_HUMAN,tr|K7EL60|K7EL60_HUMAN" 5 885.492 0.47 42938 7519 2 885.49127 443.7533 Eukaryotic translation initiation factor 3 subunit G OS=Homo sapiens OX=9606 GN=EIF3G PE=1 SV=2 6.1 1866.2 - 1.76E+06 - - - -0.8041 - 1.2 0.134 - 119.8 1 2 0 -0.0007 8 0 0 0 9.20E+07 1.94E+08 - - - 0.5804 0.9834 221125_WJC_METTL3_EV_vs_WT_F04.07520.07520.2 0.597 12-Jul K.SQDFYEK[136.11].E sp|Q8N183|NDUF2_HUMAN 1 923.4116 3.41 42939 7520 2 923.412027 462.7131 NADH dehydrogenase [ubiquinone] 1 alpha subcomplex assembly factor 2 OS=Homo sapiens OX=9606 GN=NDUFAF2 PE=1 SV=1 4.37 1866.3 - 1.79E+06 - - - 0.4494 - 1.151 0.114 - 238.8 1 2 0 0.0004 7 0 0 0 2.85E+08 8.36E+07 - - - 0.3285 0.9999 221125_WJC_METTL3_EV_vs_WT_F04.07521.07521.2 4.33E-07 22-Dec K.MASGAANVVGPK.L "sp|Q92520|FAM3C_HUMAN,tr|C9JMN4|C9JMN4_HUMAN,tr|C9JP35|C9JP35_HUMAN" 3 1100.5648 1.15 42940 7521 2 1100.56454 551.2897 Protein FAM3C OS=Homo sapiens OX=9606 GN=FAM3C PE=1 SV=1 8.5 1866.3 - 1.53E+06 - - - -0.2626 - 2.473 0.575 - 488.8 1 2 0 -0.0003 12 0 0 0 1.20E+08 1.05E+08 - - - 5.6702 0.9878 221125_WJC_METTL3_EV_vs_WT_F04.07522.07522.2 0.0227 16-Sep L.TNSMMMHGR[166.11].N "sp|P46782|RS5_HUMAN,tr|M0R0F0|M0R0F0_HUMAN,tr|M0R0R2|M0R0R2_HUMAN" 3 1073.4444 1.15 42941 7522 2 1073.443108 537.7295 40S ribosomal protein S5 OS=Homo sapiens OX=9606 GN=RPS5 PE=1 SV=4 9.44 1866.5 - 1.36E+06 - - - -1.2129 - 1.929 0.474 - 486.2 1 1 0 -0.0013 9 0 0 0 3.63E+07 3.17E+07 - - - 4.4423 0.9989 221125_WJC_METTL3_EV_vs_WT_F04.07523.07523.2 0.0162 14-Jun R.ETLEEYNK.E "sp|Q13948|CASP_HUMAN,sp|P39880|CUX1_HUMAN,tr|A0A2R8Y852|A0A2R8Y852_HUMAN,tr|A0A2R8YDI1|A0A2R8YDI1_HUMAN" 4 1024.4713 0.28 42942 7523 2 1024.472385 513.2429 Protein CASP OS=Homo sapiens OX=9606 GN=CUX1 PE=1 SV=2 4.25 1866.6 - 719511 - - - 1.0532 - 1.336 0.363 - 116 1 2 0 0.0011 8 0 0 0 3.18E+07 1.15E+08 - - - 2.5954 0.9785 221125_WJC_METTL3_EV_vs_WT_F04.07524.07524.2 0.0903 14-Aug R.QVC[160.03]PLDNR[166.11].E sp|P62877|RBX1_HUMAN 1 1010.4843 1.34 42943 7524 2 1010.488664 506.2494 E3 ubiquitin-protein ligase RBX1 OS=Homo sapiens OX=9606 GN=RBX1 PE=1 SV=1 5.83 1866.7 - 530195 - - - 4.3346 - 1.442 0.235 - 342.2 1 2 0 0.0044 8 0 0 0 2.05E+07 1.53E+07 - - - 1.8793 1 221125_WJC_METTL3_EV_vs_WT_F04.07525.07525.2 6.08E-05 14/24 K.VAEDEAEAAAAAK[136.11].F "sp|P08195|4F2_HUMAN,tr|F5H867|F5H867_HUMAN,tr|A0A7P0TAN7|A0A7P0TAN7_HUMAN,tr|J3KPF3|J3KPF3_HUMAN,tr|F5H0E2|F5H0E2_HUMAN,tr|H0YH36|H0YH36_HUMAN,tr|A0A7P0TAT7|A0A7P0TAT7_HUMAN,tr|H0YFS2|H0YFS2_HUMAN,tr|A0A7P0T8U7|A0A7P0T8U7_HUMAN,tr|A0A7P0T9F7|A0A7P0T9F7_HUMAN,tr|A0A7P0TBF8|A0A7P0TBF8_HUMAN,tr|A0A7P0T8F1|A0A7P0T8F1_HUMAN,tr|A0A7P0Z4A0|A0A7P0Z4A0_HUMAN,tr|F5GZS6|F5GZS6_HUMAN,tr|A0A7P0Z4P5|A0A7P0Z4P5_HUMAN,tr|A0A7P0T853|A0A7P0T853_HUMAN,tr|A0A7P0TAS6|A0A7P0TAS6_HUMAN" 17 1252.6027 1.44 42944 7525 2 1252.600331 627.3086 4F2 cell-surface antigen heavy chain OS=Homo sapiens OX=9606 GN=SLC3A2 PE=1 SV=3 4 1866.8 - 519246 - - - -1.8601 - 2.833 0.544 - 714.5 1 2 0 -0.0023 13 0 0 0 8.27E+07 5.76E+07 - - - 5.7309 0.9955 221125_WJC_METTL3_EV_vs_WT_F04.07528.07528.2 0.378 14-Jun K.VISELNGK.N "sp|P05387|RLA2_HUMAN,tr|H0YDD8|H0YDD8_HUMAN" 2 858.4811 1.17 42945 7528 2 858.48065 430.2478 60S acidic ribosomal protein P2 OS=Homo sapiens OX=9606 GN=RPLP2 PE=1 SV=1 5.97 1867.2 - 2.30E+06 - - - -0.5044 - 1.092 0.255 - 106.6 1 2 0 -0.0004 8 0 0 0 1.77E+08 1.51E+08 - - - 1.1897 0.9316 221125_WJC_METTL3_EV_vs_WT_F04.07529.07529.2 0.905 12-Aug R.FR[166.11]DPDLR[166.11].Q "sp|O43251|RFOX2_HUMAN,sp|Q9NWB1|RFOX1_HUMAN,sp|A6NFN3|RFOX3_HUMAN,tr|A0A6Q8PGE0|A0A6Q8PGE0_HUMAN,tr|A0A6Q8PH77|A0A6Q8PH77_HUMAN,tr|A0A286YEU2|A0A286YEU2_HUMAN,tr|A0A087X2B1|A0A087X2B1_HUMAN,tr|F8VR27|F8VR27_HUMAN,tr|B7Z1U7|B7Z1U7_HUMAN,tr|B0QYY6|B0QYY6_HUMAN,tr|B0QYV1|B0QYV1_HUMAN,tr|A0A6Q8PHA3|A0A6Q8PHA3_HUMAN,tr|A0A3B3ITL7|A0A3B3ITL7_HUMAN,tr|F8VZY7|F8VZY7_HUMAN,tr|B0QYY4|B0QYY4_HUMAN,tr|J3KNW3|J3KNW3_HUMAN,tr|F8VZG9|F8VZG9_HUMAN,tr|J3QRF4|J3QRF4_HUMAN,tr|F8VRS4|F8VRS4_HUMAN,tr|A0A6Q8PFM4|A0A6Q8PFM4_HUMAN,tr|S4R469|S4R469_HUMAN,tr|A0A804HKG7|A0A804HKG7_HUMAN,tr|A0A0G2JRA5|A0A0G2JRA5_HUMAN,tr|A0A804HJM2|A0A804HJM2_HUMAN,tr|J3QQZ2|J3QQZ2_HUMAN,tr|I3L1D4|I3L1D4_HUMAN,tr|B0QYY7|B0QYY7_HUMAN,tr|A0A0G2JSB3|A0A0G2JSB3_HUMAN" 28 937.4885 1.2 42946 7529 2 937.488433 469.7515 RNA binding protein fox-1 homolog 2 OS=Homo sapiens OX=9606 GN=RBFOX2 PE=1 SV=3 5.96 1867.3 - 1.96E+06 - - - -0.0235 - 1.384 0.114 - 315.8 1 2 1 0 7 0 0 0 8.43E+08 7.05E+08 - - - 0.9127 0.9982 221125_WJC_METTL3_EV_vs_WT_F04.07531.07531.2 0.0408 14-Aug R.SVSQETFR[166.11].L "sp|Q75N03|HAKAI_HUMAN,tr|C9J2P9|C9J2P9_HUMAN" 2 962.4697 0.75 42948 7531 2 962.468384 482.2421 E3 ubiquitin-protein ligase Hakai OS=Homo sapiens OX=9606 GN=CBLL1 PE=1 SV=1 5.72 1867.4 - 1.74E+06 - - - -1.3465 - 1.324 0.307 - 196.1 1 2 0 -0.0013 8 0 0 0 3.09E+07 4.11E+07 - - - 2.1545 0.9977 221125_WJC_METTL3_EV_vs_WT_F04.07538.07538.2 0.0735 14-Aug K.VISELNGK[136.11].N "sp|P05387|RLA2_HUMAN,tr|H0YDD8|H0YDD8_HUMAN" 2 866.4953 1.18 42953 7538 2 866.494761 434.2549 60S acidic ribosomal protein P2 OS=Homo sapiens OX=9606 GN=RPLP2 PE=1 SV=1 5.97 1868.1 - 3.24E+06 - - - -0.6024 - 1.352 0.238 - 184.4 1 2 0 -0.0005 8 0 0 0 1.78E+08 1.51E+08 - - - 1.7083 0.9996 221125_WJC_METTL3_EV_vs_WT_F04.07539.07539.2 7.65E-05 20-Sep K.VMATTGGTNLR.D sp|P26196|DDX6_HUMAN 1 1119.5706 1.04 42954 7539 2 1119.57263 560.7926 Probable ATP-dependent RNA helicase DDX6 OS=Homo sapiens OX=9606 GN=DDX6 PE=1 SV=2 9.72 1868.3 - 316549 - - - 1.7748 - 1.973 0.433 - 337.6 1 2 0 0.002 11 0 0 0 3.46E+07 3.32E+07 - - - 4.0769 0.9866 221125_WJC_METTL3_EV_vs_WT_F04.07543.07543.2 0.359 16-Sep K.QLNAIESTK[136.11].L "sp|Q92576|PHF3_HUMAN,tr|E9PE34|E9PE34_HUMAN,tr|E7EVH3|E7EVH3_HUMAN,tr|D6R9X2|D6R9X2_HUMAN,tr|A0A1B0GX99|A0A1B0GX99_HUMAN" 5 1010.5488 3.32 42956 7543 2 1010.546772 506.2817 PHD finger protein 3 OS=Homo sapiens OX=9606 GN=PHF3 PE=1 SV=3 6 1868.8 - 432203 - - - -1.9821 - 1.391 0.127 - 337.7 1 2 0 -0.002 9 0 0 0 4.66E+07 1.41E+07 - - - 0.9332 0.9865 221125_WJC_METTL3_EV_vs_WT_F04.07553.07553.2 0.000995 22-Oct N.LGAGNGNLQGPR[166.11].H "sp|P43243|MATR3_HUMAN,tr|D6RE02|D6RE02_HUMAN,tr|B3KM87|B3KM87_HUMAN,tr|A8MXP9|A8MXP9_HUMAN,tr|D6RAY2|D6RAY2_HUMAN,tr|D6R991|D6R991_HUMAN,tr|A0A0R4J2E8|A0A0R4J2E8_HUMAN,tr|D6RAM9|D6RAM9_HUMAN,tr|D6RIA2|D6RIA2_HUMAN,tr|H0Y8T4|H0Y8T4_HUMAN,tr|D6REM6|D6REM6_HUMAN,tr|D6RBI2|D6RBI2_HUMAN" 12 1162.6082 1.97 42960 7553 2 1162.607706 582.3114 Matrin-3 OS=Homo sapiens OX=9606 GN=MATR3 PE=1 SV=2 9.75 1870.1 - 165536 - - - -0.4585 - 2.133 0.393 - 277.3 1 1 0 -0.0005 12 0 0 0 4.85E+06 2.47E+06 - - - 3.9367 0.9993 221125_WJC_METTL3_EV_vs_WT_F04.07555.07555.2 0.0049 16-Sep R.C[160.03]VIMC[160.03]QGSK.K sp|O75643|U520_HUMAN 1 1081.4719 1.99 42961 7555 2 1081.472797 541.7432 U5 small nuclear ribonucleoprotein 200 kDa helicase OS=Homo sapiens OX=9606 GN=SNRNP200 PE=1 SV=2 8.06 1870.3 - 1.23E+06 - - - 0.8692 - 1.403 0.382 - 198.3 1 2 0 0.0009 9 0 0 0 3.37E+07 1.70E+07 - - - 2.8418 0.9996 221125_WJC_METTL3_EV_vs_WT_F04.07557.07557.2 6.58E-05 18-Sep R.AAQVMGPPDR.C sp|Q96I24|FUBP3_HUMAN 1 1040.5073 1.73 42962 7557 2 1040.507105 521.2609 Far upstream element-binding protein 3 OS=Homo sapiens OX=9606 GN=FUBP3 PE=1 SV=2 5.88 1870.5 - 1.22E+07 - - - -0.2009 - 1.962 0.322 - 355 1 2 0 -0.0002 10 0 0 0 4.19E+08 2.42E+08 - - - 3.3005 0.9057 221125_WJC_METTL3_EV_vs_WT_F04.07558.07558.2 0.118 14-Jul L.EAQITDVR.Q "sp|P35527|K1C9_HUMAN,tr|K7EQQ3|K7EQQ3_HUMAN" 2 930.4771 16.32 42963 7558 2 930.476727 466.2458 "Keratin, type I cytoskeletal 9 OS=Homo sapiens OX=9606 GN=KRT9 PE=1 SV=3" 4.37 1870.6 - 1.78E+06 - - - -0.3579 - 1.538 0.213 - 222.2 1 1 0 -0.0003 8 0 0 0 1.88E+08 1.15E+07 - - - 1.9124 0.9467 221125_WJC_METTL3_EV_vs_WT_F04.07560.07560.2 0.0294 20-Sep F.VLAPEGSVANK.F "sp|Q13283|G3BP1_HUMAN,tr|A0A7I2V5M7|A0A7I2V5M7_HUMAN,tr|A0A7P0P2U7|A0A7P0P2U7_HUMAN,tr|A0A7I2YQU8|A0A7I2YQU8_HUMAN,tr|A0A7I2V651|A0A7I2V651_HUMAN,tr|A0A7I2YQN9|A0A7I2YQN9_HUMAN,tr|A0A7I2V2V1|A0A7I2V2V1_HUMAN" 7 1083.5924 1.23 42965 7560 2 1083.591976 542.8035 Ras GTPase-activating protein-binding protein 1 OS=Homo sapiens OX=9606 GN=G3BP1 PE=1 SV=1 5.97 1870.7 - 1.31E+06 - - - -0.4134 - 1.562 0.297 - 272.2 1 1 0 -0.0004 11 0 0 0 1.93E+08 1.57E+08 - - - 2.4409 0.9991 221125_WJC_METTL3_EV_vs_WT_F04.07563.07563.2 0.0602 18-Aug R.GPASVPSVGK[136.11].A "sp|Q13428|TCOF_HUMAN,tr|H0YAB7|H0YAB7_HUMAN,tr|E7ETY2|E7ETY2_HUMAN,tr|H0Y8Y7|H0Y8Y7_HUMAN,tr|A0A3B3IS06|A0A3B3IS06_HUMAN,tr|A0A6I8PRA0|A0A6I8PRA0_HUMAN" 6 905.5062 1.01 42966 7563 2 905.505756 453.7604 Treacle protein OS=Homo sapiens OX=9606 GN=TCOF1 PE=1 SV=3 8.75 1871.1 - 952012 - - - -0.4705 - 1.402 0.338 - 149.6 1 2 0 -0.0004 10 0 0 0 5.23E+07 5.19E+07 - - - 2.4805 0.9791 221125_WJC_METTL3_EV_vs_WT_F04.07566.07566.2 0.00124 20-Sep F.VLAPEGSVANK[136.11].F "sp|Q13283|G3BP1_HUMAN,tr|A0A7I2V5M7|A0A7I2V5M7_HUMAN,tr|A0A7P0P2U7|A0A7P0P2U7_HUMAN,tr|A0A7I2YQU8|A0A7I2YQU8_HUMAN,tr|A0A7I2V651|A0A7I2V651_HUMAN,tr|A0A7I2YQN9|A0A7I2YQN9_HUMAN,tr|A0A7I2V2V1|A0A7I2V2V1_HUMAN" 7 1091.6066 1.23 42968 7566 2 1091.607372 546.8106 Ras GTPase-activating protein-binding protein 1 OS=Homo sapiens OX=9606 GN=G3BP1 PE=1 SV=1 5.97 1871.4 - 2.18E+06 - - - 0.6852 - 1.86 0.383 - 252.2 1 1 0 0.0007 11 0 0 0 1.93E+08 1.57E+08 - - - 3.5484 0.9998 221125_WJC_METTL3_EV_vs_WT_F04.07567.07567.2 0.000423 18-Jul R.AAQVMGPPDR[166.11].C sp|Q96I24|FUBP3_HUMAN 1 1050.5156 1.84 42969 7567 2 1050.515557 526.2651 Far upstream element-binding protein 3 OS=Homo sapiens OX=9606 GN=FUBP3 PE=1 SV=2 5.88 1871.4 - 7.10E+06 - - - -0.0257 - 1.8 0.449 - 199.8 1 2 0 0 10 0 0 0 6.70E+08 3.64E+08 - - - 3.998 0.9991 221125_WJC_METTL3_EV_vs_WT_F04.07570.07570.2 0.00487 14-Aug K.QQEIVVSR.G "sp|Q15393|SF3B3_HUMAN,tr|I3L4G7|I3L4G7_HUMAN" 2 957.5243 1.12 42970 7570 2 957.524046 479.7694 Splicing factor 3B subunit 3 OS=Homo sapiens OX=9606 GN=SF3B3 PE=1 SV=4 6 1871.8 - 1.16E+07 - - - -0.3112 - 1.784 0.227 - 304.1 1 2 0 -0.0003 8 0 0 0 2.74E+08 2.45E+08 - - - 2.4633 0.998 221125_WJC_METTL3_EV_vs_WT_F04.07571.07571.2 0.309 12-Aug R.SQSLNIR.T "sp|O00443|P3C2A_HUMAN,tr|A0A0C4DGF9|A0A0C4DGF9_HUMAN" 2 816.4454 1.04 42971 7571 2 816.445748 409.23 Phosphatidylinositol 4-phosphate 3-kinase C2 domain-containing subunit alpha OS=Homo sapiens OX=9606 GN=PIK3C2A PE=1 SV=2 9.47 1871.9 - 1.74E+06 - - - 0.4679 - 1.506 0.207 - 333.9 1 2 0 0.0004 7 0 0 0 5.80E+07 5.58E+07 - - - 1.8672 0.9508 221125_WJC_METTL3_EV_vs_WT_F04.07579.07579.2 0.12 12-Jun R.FRDPDLR.Q "sp|O43251|RFOX2_HUMAN,sp|Q9NWB1|RFOX1_HUMAN,sp|A6NFN3|RFOX3_HUMAN,tr|A0A6Q8PGE0|A0A6Q8PGE0_HUMAN,tr|A0A6Q8PH77|A0A6Q8PH77_HUMAN,tr|A0A286YEU2|A0A286YEU2_HUMAN,tr|A0A087X2B1|A0A087X2B1_HUMAN,tr|F8VR27|F8VR27_HUMAN,tr|B7Z1U7|B7Z1U7_HUMAN,tr|B0QYY6|B0QYY6_HUMAN,tr|B0QYV1|B0QYV1_HUMAN,tr|A0A6Q8PHA3|A0A6Q8PHA3_HUMAN,tr|A0A3B3ITL7|A0A3B3ITL7_HUMAN,tr|F8VZY7|F8VZY7_HUMAN,tr|B0QYY4|B0QYY4_HUMAN,tr|J3KNW3|J3KNW3_HUMAN,tr|F8VZG9|F8VZG9_HUMAN,tr|J3QRF4|J3QRF4_HUMAN,tr|F8VRS4|F8VRS4_HUMAN,tr|A0A6Q8PFM4|A0A6Q8PFM4_HUMAN,tr|S4R469|S4R469_HUMAN,tr|A0A804HKG7|A0A804HKG7_HUMAN,tr|A0A0G2JRA5|A0A0G2JRA5_HUMAN,tr|A0A804HJM2|A0A804HJM2_HUMAN,tr|J3QQZ2|J3QQZ2_HUMAN,tr|I3L1D4|I3L1D4_HUMAN,tr|B0QYY7|B0QYY7_HUMAN,tr|A0A0G2JSB3|A0A0G2JSB3_HUMAN" 28 917.4719 1.2 42977 7579 2 917.471129 459.7432 RNA binding protein fox-1 homolog 2 OS=Homo sapiens OX=9606 GN=RBFOX2 PE=1 SV=3 5.96 1872.8 - 2.11E+07 - - - -0.8567 - 1.276 0.195 - 175.8 1 2 1 -0.0008 7 0 0 0 8.43E+08 7.05E+08 - - - 1.2533 0.9997 221125_WJC_METTL3_EV_vs_WT_F04.07580.07580.2 0.0026 18-Oct K.LLEVEHPAAK.V "sp|P17987|TCPA_HUMAN,tr|F5H726|F5H726_HUMAN,tr|F5H136|F5H136_HUMAN,tr|F5GZI8|F5GZI8_HUMAN,tr|E7ERF2|E7ERF2_HUMAN,tr|F5H676|F5H676_HUMAN" 6 1105.6132 0.47 42978 7580 2 1105.612678 553.8139 T-complex protein 1 subunit alpha OS=Homo sapiens OX=9606 GN=TCP1 PE=1 SV=1 5.4 1872.8 - 3.08E+06 - - - -0.4351 - 1.912 0.398 - 308 1 2 0 -0.0005 10 0 0 0 1.69E+08 3.57E+08 - - - 3.7897 0.9935 221125_WJC_METTL3_EV_vs_WT_F04.07581.07581.2 0.255 14-Apr K.DYAESVGR.K sp|Q9HCD5|NCOA5_HUMAN 1 895.4036 1.5 42979 7581 2 895.403491 448.7091 Nuclear receptor coactivator 5 OS=Homo sapiens OX=9606 GN=NCOA5 PE=1 SV=2 4.37 1872.9 - 1.81E+06 - - - -0.0771 - 1.012 0.299 - 40.9 7 2 0 -0.0001 8 0 0 0 2.63E+08 1.76E+08 - - - 0.9079 0.9982 221125_WJC_METTL3_EV_vs_WT_F04.07589.07589.2 0.0993 16-Sep R.FLNAENAQK.F "sp|P43487|RANG_HUMAN,tr|C9JXG8|C9JXG8_HUMAN,tr|F6WQW2|F6WQW2_HUMAN,tr|C9JGV6|C9JGV6_HUMAN" 4 1033.5193 0.99 42985 7589 2 1033.519947 517.7669 Ran-specific GTPase-activating protein OS=Homo sapiens OX=9606 GN=RANBP1 PE=1 SV=1 6 1873.7 - 2.44E+06 - - - 0.6657 - 1.568 0.224 - 190.4 1 2 0 0.0007 9 0 0 0 1.51E+08 1.52E+08 - - - 1.9965 0.9994 221125_WJC_METTL3_EV_vs_WT_F04.07592.07592.2 0.00406 20-Nov R.GPDELEGPDSK.L sp|P48634|PRC2A_HUMAN 1 1142.5091 1.59 42988 7592 2 1142.505294 572.2619 Protein PRRC2A OS=Homo sapiens OX=9606 GN=PRRC2A PE=1 SV=3 3.92 1874.1 - 285796 - - - -3.3733 - 2.293 0.513 - 387.6 1 2 0 -0.0039 11 0 0 0 1.19E+07 7.48E+06 - - - 5.0738 0.9926 221125_WJC_METTL3_EV_vs_WT_F04.07598.07598.2 0.808 14-Aug K.LLSISGKR.S "sp|P06748|NPM_HUMAN,tr|E5RI98|E5RI98_HUMAN,tr|A0A7I2YQC0|A0A7I2YQC0_HUMAN,tr|A0A7I2V433|A0A7I2V433_HUMAN,tr|A0A7I2V2X9|A0A7I2V2X9_HUMAN,tr|A0A7I2V5J8|A0A7I2V5J8_HUMAN,tr|A0A7I2V5S2|A0A7I2V5S2_HUMAN,tr|A0A7I2V3U2|A0A7I2V3U2_HUMAN" 8 872.5444 0.64 42992 7598 2 872.542967 437.2795 Nucleophosmin OS=Homo sapiens OX=9606 GN=NPM1 PE=1 SV=2 11 1874.8 - 653781 - - - -1.5862 - 1.477 0.129 - 153.3 1 2 0 -0.0014 8 0 0 0 1.19E+07 1.86E+07 - - - 1.1696 0.9522 221125_WJC_METTL3_EV_vs_WT_F04.07599.07599.2 6.07 14-Jun R.LAHEVGWK[136.11].Y "sp|P40429|RL13A_HUMAN,tr|M0QYS1|M0QYS1_HUMAN,tr|Q8J015|Q8J015_HUMAN,tr|A0A7I2V2L9|A0A7I2V2L9_HUMAN,tr|A0A7I2V5L3|A0A7I2V5L3_HUMAN" 5 946.5116 8.37 42993 7599 2 946.511358 474.2631 60S ribosomal protein L13a OS=Homo sapiens OX=9606 GN=RPL13A PE=1 SV=2 6.75 1874.8 - 2.54E+06 - - - -0.2567 - 1.132 0.042 - 86 2 2 0 -0.0002 8 0 0 0 3.29E+08 3.93E+07 - - - -0.4094 0.9997 221125_WJC_METTL3_EV_vs_WT_F04.07600.07600.2 0.0928 12-May R.DDFTEER.L sp|P21912|SDHB_HUMAN 1 910.3668 0.62 42994 7600 2 910.367086 456.1907 "Succinate dehydrogenase [ubiquinone] iron-sulfur subunit, mitochondrial OS=Homo sapiens OX=9606 GN=SDHB PE=1 SV=3" 3.92 1874.9 - 772127 - - - 0.2691 - 1.386 0.466 - 109.2 1 2 0 0.0002 7 0 0 0 5.73E+07 9.23E+07 - - - 3.5171 0.9956 221125_WJC_METTL3_EV_vs_WT_F04.07608.07608.2 0.338 14-Jul R.TIEELQNK.L "sp|Q04695|K1C17_HUMAN,tr|K7EPJ9|K7EPJ9_HUMAN,tr|F5GWP8|F5GWP8_HUMAN" 3 973.508 606.18 42998 7608 2 973.507776 487.7613 "Keratin, type I cytoskeletal 17 OS=Homo sapiens OX=9606 GN=KRT17 PE=1 SV=2" 4.53 1875.9 - 9.34E+06 - - - -0.2568 - 1.357 0.167 - 116.3 1 2 0 -0.0003 8 0 0 0 5.10E+09 8.41E+06 - - - 1.1951 0.9998 221125_WJC_METTL3_EV_vs_WT_F04.07609.07609.2 0.000121 18-Jul R.EMDDPSVGPK.L "sp|Q13435|SF3B2_HUMAN,tr|E9PPJ0|E9PPJ0_HUMAN,tr|H0YCG1|H0YCG1_HUMAN,tr|E9PJ04|E9PJ04_HUMAN,tr|E9PJT3|E9PJT3_HUMAN" 5 1073.4699 0.03 42999 7609 2 1073.468648 537.7422 Splicing factor 3B subunit 2 OS=Homo sapiens OX=9606 GN=SF3B2 PE=1 SV=2 4.03 1876 - 887724 - - - -1.1905 - 1.572 0.529 - 167.3 1 2 0 -0.0013 10 0 0 0 2.86E+07 9.80E+08 - - - 4.2104 0.9934 221125_WJC_METTL3_EV_vs_WT_F04.07610.07610.2 0.12 12-Jun R.DFTSEPR[166.11].L "sp|Q2VIR3|IF2GL_HUMAN,sp|P41091|IF2G_HUMAN" 2 860.3904 0.7 43000 7610 2 860.391517 431.2025 Eukaryotic translation initiation factor 2 subunit 3B OS=Homo sapiens OX=9606 GN=EIF2S3B PE=2 SV=2 4.37 1876.1 - 2.06E+06 - - - 1.3366 - 1.024 0.286 - 151.6 1 2 0 0.0012 7 0 0 0 8.30E+07 1.19E+08 - - - 1.2282 0.9997 221125_WJC_METTL3_EV_vs_WT_F04.07615.07615.2 0.0033 16-Oct K.LSDLDSETR.S sp|Q9Y266|NUDC_HUMAN 1 1034.488 1.65 43003 7615 2 1034.487271 518.2513 Nuclear migration protein nudC OS=Homo sapiens OX=9606 GN=NUDC PE=1 SV=1 4.03 1876.7 - 8.74E+06 - - - -0.7221 - 2.027 0.373 - 344.4 1 2 0 -0.0007 9 0 0 0 1.04E+09 6.33E+08 - - - 3.8398 1 221125_WJC_METTL3_EV_vs_WT_F04.07618.07618.2 7.99E-10 14/24 K.APAPEAEDEEVAR[166.11].R sp|Q8NBN7|RDH13_HUMAN 1 1392.6397 0.93 43005 7618 2 1392.636402 697.3271 Retinol dehydrogenase 13 OS=Homo sapiens OX=9606 GN=RDH13 PE=1 SV=2 3.91 1877 - 177254 - - - -2.338 - 2.549 0.716 - 713.9 1 2 0 -0.0033 13 0 0 0 6.33E+06 6.83E+06 - - - 6.7299 0.9997 221125_WJC_METTL3_EV_vs_WT_F04.07620.07620.2 0.0218 16-Sep R.IQNPSAYAK.R "sp|Q92615|LAR4B_HUMAN,tr|H0Y4V9|H0Y4V9_HUMAN" 2 990.5134 0.63 43006 7620 2 990.513113 496.264 La-related protein 4B OS=Homo sapiens OX=9606 GN=LARP4B PE=1 SV=3 8.59 1877.2 - 1.68E+07 - - - -0.3352 - 1.912 0.378 - 210.1 1 2 0 -0.0003 9 0 0 0 6.73E+08 1.07E+09 - - - 3.7079 0.9989 221125_WJC_METTL3_EV_vs_WT_F04.07622.07622.2 0.00506 18-Sep R.ALSQGVESVK.K "sp|O43615|TIM44_HUMAN,tr|M0QXU7|M0QXU7_HUMAN" 2 1016.5502 1.29 43007 7622 2 1016.551215 509.2824 Mitochondrial import inner membrane translocase subunit TIM44 OS=Homo sapiens OX=9606 GN=TIMM44 PE=1 SV=2 6.05 1877.4 - 3.23E+06 - - - 0.9739 - 1.49 0.319 - 237.1 1 2 0 0.001 10 0 0 0 1.85E+08 1.43E+08 - - - 2.5099 0.9985 221125_WJC_METTL3_EV_vs_WT_F04.07624.07624.2 0.0938 12-Jul R.DFTSEPR.L "sp|Q2VIR3|IF2GL_HUMAN,sp|P41091|IF2G_HUMAN" 2 850.3821 0.59 43009 7624 2 850.381652 426.1983 Eukaryotic translation initiation factor 2 subunit 3B OS=Homo sapiens OX=9606 GN=EIF2S3B PE=2 SV=2 4.37 1877.6 - 1.41E+06 - - - -0.5233 - 1.408 0.257 - 248 1 2 0 -0.0004 7 0 0 0 9.02E+07 1.53E+08 - - - 2.0232 0.9696 221125_WJC_METTL3_EV_vs_WT_F04.07627.07627.2 0.000964 14-Aug K.ETGYVVER.P "sp|Q9NYF8|BCLF1_HUMAN,tr|E9PKI6|E9PKI6_HUMAN,tr|A0A1W2PQ43|A0A1W2PQ43_HUMAN,tr|E9PK91|E9PK91_HUMAN,tr|E9PK09|E9PK09_HUMAN,tr|E9PQN2|E9PQN2_HUMAN" 6 951.4662 0.9 43010 7627 2 951.465755 476.7404 Bcl-2-associated transcription factor 1 OS=Homo sapiens OX=9606 GN=BCLAF1 PE=1 SV=2 4.53 1878 - 2.58E+06 - - - -0.4267 - 1.654 0.33 - 283.2 1 1 0 -0.0004 8 0 0 0 1.46E+08 1.62E+08 - - - 2.9959 0.9972 221125_WJC_METTL3_EV_vs_WT_F04.07628.07628.2 0.0442 20-Jul K.IVNSAQTGSFK[136.11].Q "sp|O75964|ATP5L_HUMAN,tr|A0A3B3ITX4|A0A3B3ITX4_HUMAN,tr|E9PN17|E9PN17_HUMAN" 3 1158.6124 1.38 43011 7628 2 1158.611112 580.3135 "ATP synthase subunit g, mitochondrial OS=Homo sapiens OX=9606 GN=ATP5MG PE=1 SV=3" 8.75 1878.1 - 411500 - - - -1.1445 - 1.422 0.234 - 60.2 1 2 0 -0.0013 11 0 0 0 1.57E+07 1.13E+07 - - - 1.7213 0.9999 221125_WJC_METTL3_EV_vs_WT_F04.07631.07631.2 9.08E-06 20-Oct K.IVNSAQTGSFK.Q "sp|O75964|ATP5L_HUMAN,tr|A0A3B3ITX4|A0A3B3ITX4_HUMAN,tr|E9PN17|E9PN17_HUMAN" 3 1150.5982 1.17 43012 7631 2 1150.598045 576.3064 "ATP synthase subunit g, mitochondrial OS=Homo sapiens OX=9606 GN=ATP5MG PE=1 SV=3" 8.75 1878.5 - 308702 - - - -0.1677 - 1.975 0.499 - 259.7 1 2 0 -0.0002 11 0 0 0 1.26E+07 1.08E+07 - - - 4.5677 0.9831 221125_WJC_METTL3_EV_vs_WT_F04.07633.07633.2 0.521 20-Oct R.ILAQSNNQQLR[166.11].D "sp|Q14686|NCOA6_HUMAN,tr|F6M2K2|F6M2K2_HUMAN,tr|F6M2K4|F6M2K4_HUMAN" 3 1293.7029 1.9 43013 7633 2 1293.703218 647.8587 Nuclear receptor coactivator 6 OS=Homo sapiens OX=9606 GN=NCOA6 PE=1 SV=3 9.75 1878.8 - 172213 - - - 0.2705 - 1.251 0.087 - 428.7 1 2 0 0.0003 11 0 0 0 6.46E+06 3.40E+06 - - - 0.2893 0.9936 221125_WJC_METTL3_EV_vs_WT_F04.07638.07638.2 0.000273 14-Sep K.C[160.03]GNVNFAR[166.11].R sp|O95218|ZRAB2_HUMAN 1 946.4319 1.23 43015 7638 2 946.427387 474.2232 Zinc finger Ran-binding domain-containing protein 2 OS=Homo sapiens OX=9606 GN=ZRANB2 PE=1 SV=2 8.25 1879.4 - 772982 - - - -4.7209 - 2.023 0.281 - 395.4 1 2 0 -0.0045 8 0 0 0 3.56E+07 2.90E+07 - - - 3.24 0.9995 221125_WJC_METTL3_EV_vs_WT_F04.07640.07640.2 0.0302 18-Oct R.ALSQGVESVK[136.11].K "sp|O43615|TIM44_HUMAN,tr|M0QXU7|M0QXU7_HUMAN" 2 1024.5644 1.29 43016 7640 2 1024.564215 513.2895 Mitochondrial import inner membrane translocase subunit TIM44 OS=Homo sapiens OX=9606 GN=TIMM44 PE=1 SV=2 6.05 1879.6 - 5.64E+06 - - - -0.205 - 1.832 0.309 - 316.2 1 2 0 -0.0002 10 0 0 0 1.85E+08 1.43E+08 - - - 3.0131 0.9996 221125_WJC_METTL3_EV_vs_WT_F04.07641.07641.2 0.00418 18-Sep R.IAELSEDDQK[136.11].L sp|Q9BZE4|GTPB4_HUMAN 1 1154.5546 1.87 43017 7641 2 1154.555215 578.2846 GTP-binding protein 4 OS=Homo sapiens OX=9606 GN=GTPBP4 PE=1 SV=3 3.92 1879.7 - 287233 - - - 0.4911 - 2.101 0.305 - 201.2 1 2 0 0.0006 10 0 0 0 2.69E+07 1.44E+07 - - - 3.3659 0.9995 221125_WJC_METTL3_EV_vs_WT_F04.07642.07642.2 0.000426 16-Oct K.LEVQAEEER.K sp|Q9H307|PININ_HUMAN 1 1101.5302 1.82 43018 7642 2 1101.529839 551.7724 Pinin OS=Homo sapiens OX=9606 GN=PNN PE=1 SV=5 4.09 1879.8 - 3.30E+06 - - - -0.3441 - 2.137 0.255 - 533 1 2 0 -0.0004 9 0 0 0 4.45E+08 2.45E+08 - - - 3.1213 0.9986 221125_WJC_METTL3_EV_vs_WT_F04.07644.07644.2 0.0369 14-Jul R.SDIMPSGR[166.11].S "sp|Q8TB72|PUM2_HUMAN,tr|A0A0C4DG68|A0A0C4DG68_HUMAN" 2 871.4097 1.63 43020 7644 2 871.409701 436.7121 Pumilio homolog 2 OS=Homo sapiens OX=9606 GN=PUM2 PE=1 SV=2 5.55 1880 - 932891 - - - -0.0241 - 1.323 0.301 - 143 1 2 0 0 8 0 0 0 1.61E+08 9.85E+07 - - - 2.1084 0.7998 221125_WJC_METTL3_EV_vs_WT_F04.07645.07645.2 0.476 16-Jul R.LFEGSASR[166.11]W.- tr|A8MXK4|A8MXK4_HUMAN 1 1061.517 22.41 43021 7645 2 1061.523139 531.7658 40S ribosomal protein S9 OS=Homo sapiens OX=9606 GN=RPS9 PE=1 SV=1 6 1880.1 - 399558 - - - 5.8171 - 1.314 0.138 - 90.4 1 2 0 0.0062 9 0 0 0 1.44E+08 6.42E+06 - - - 0.8484 0.9984 221125_WJC_METTL3_EV_vs_WT_F04.07650.07650.2 0.0147 20-Sep R.ILAQSNNQQLR.D "sp|Q14686|NCOA6_HUMAN,tr|F6M2K2|F6M2K2_HUMAN,tr|F6M2K4|F6M2K4_HUMAN" 3 1283.6946 1.9 43024 7650 2 1283.69278 642.8546 Nuclear receptor coactivator 6 OS=Homo sapiens OX=9606 GN=NCOA6 PE=1 SV=3 9.75 1880.7 - 268188 - - - -1.4162 - 1.627 0.263 - 173.8 1 2 0 -0.0018 11 0 0 0 6.46E+06 3.40E+06 - - - 2.2997 0.9993 221125_WJC_METTL3_EV_vs_WT_F04.07653.07653.2 0.0791 16-Aug K.LEVQAEEER[166.11].K sp|Q9H307|PININ_HUMAN 1 1111.5385 1.82 43025 7653 2 1111.536683 556.7765 Pinin OS=Homo sapiens OX=9606 GN=PNN PE=1 SV=5 4.09 1881.1 - 4.72E+06 - - - -1.6239 - 1.892 0.315 - 262.2 1 2 0 -0.0018 9 0 0 0 4.45E+08 2.45E+08 - - - 3.2117 0.9973 221125_WJC_METTL3_EV_vs_WT_F04.07655.07655.2 0.0242 12-Jul K.DC[160.03]EGLPR[166.11].E sp|Q9H0D6|XRN2_HUMAN 1 855.3784 1.16 43027 7655 2 855.377718 428.6965 5'-3' exoribonuclease 2 OS=Homo sapiens OX=9606 GN=XRN2 PE=1 SV=1 4.37 1881.2 - 2.24E+06 - - - -0.823 - 1.29 0.242 - 295.1 1 2 0 -0.0007 7 0 0 0 2.04E+08 1.76E+08 - - - 1.635 0.9946 221125_WJC_METTL3_EV_vs_WT_F04.07656.07656.2 0.0421 12-Jun R.GSFQVTR.A "sp|P51659|DHB4_HUMAN,tr|A0A2R8YD50|A0A2R8YD50_HUMAN,tr|E7ER27|E7ER27_HUMAN,tr|A0A2R8YF45|A0A2R8YF45_HUMAN,tr|E7EPL9|E7EPL9_HUMAN,tr|A0A804HKU2|A0A804HKU2_HUMAN,tr|A0A2R8YDT8|A0A2R8YDT8_HUMAN,tr|A0A804HK65|A0A804HK65_HUMAN" 8 793.4083 0.59 43028 7656 2 793.40733 397.7114 Peroxisomal multifunctional enzyme type 2 OS=Homo sapiens OX=9606 GN=HSD17B4 PE=1 SV=3 9.75 1881.3 - 1.52E+06 - - - -1.1621 - 1.279 0.191 - 156.3 1 2 0 -0.0009 7 0 0 0 4.52E+07 7.67E+07 - - - 1.2311 0.9808 221125_WJC_METTL3_EV_vs_WT_F04.07658.07658.2 0.138 12-Jul K.SQIPLSK[136.11].L sp|P13010|XRCC5_HUMAN 1 779.4633 0.99 43030 7658 2 779.462356 390.7389 X-ray repair cross-complementing protein 5 OS=Homo sapiens OX=9606 GN=XRCC5 PE=1 SV=3 8.47 1881.6 - 1.12E+06 - - - -1.1521 - 1.462 0.014 - 291.1 1 2 0 -0.0009 7 0 0 0 3.25E+08 3.27E+08 - - - 0.3476 0.9856 221125_WJC_METTL3_EV_vs_WT_F04.07663.07663.2 0.0923 16-Jun R.AYSSFGGGR[166.11].G "sp|Q15056|IF4H_HUMAN,tr|A0A7I2V4V9|A0A7I2V4V9_HUMAN,tr|A0A7I2V385|A0A7I2V385_HUMAN" 3 910.4172 0.88 43033 7663 2 910.415988 456.2159 Eukaryotic translation initiation factor 4H OS=Homo sapiens OX=9606 GN=EIF4H PE=1 SV=5 8.79 1882.2 - 1.21E+06 - - - -1.3862 - 1.172 0.152 - 101.8 1 2 0 -0.0013 9 0 0 0 3.15E+07 3.57E+07 - - - 0.6224 0.8613 221125_WJC_METTL3_EV_vs_WT_F04.07664.07664.2 0.0525 16-Jun N.LTFMNESER[166.11].N "sp|Q8IZP7|H6ST3_HUMAN,tr|A0A087X0G1|A0A087X0G1_HUMAN" 2 1135.5207 0 43034 7664 2 1135.519705 568.7676 Heparan-sulfate 6-O-sulfotransferase 3 OS=Homo sapiens OX=9606 GN=HS6ST3 PE=2 SV=3 4.53 1882.3 - 476044 - - - -0.9018 - 1.231 0.275 - 106.6 1 1 0 -0.001 9 0 0 0 1.04E+05 6.51E+07 - - - 1.6731 0.9988 221125_WJC_METTL3_EV_vs_WT_F04.07666.07666.2 0.00287 18-Nov K.QFIAAQGSSR[166.11].S "sp|P07814|SYEP_HUMAN,tr|V9GYZ6|V9GYZ6_HUMAN" 2 1073.5493 1.21 43035 7666 2 1073.551718 537.7819 Bifunctional glutamate\proline--tRNA ligase OS=Homo sapiens OX=9606 GN=EPRS1 PE=1 SV=5 9.75 1882.5 - 532535 - - - 2.2272 - 1.72 0.35 - 333.1 1 2 0 0.0024 10 0 0 0 1.41E+07 1.17E+07 - - - 3.1391 0.9998 221125_WJC_METTL3_EV_vs_WT_F04.07676.07676.2 0.000769 18-Dec K.YEELQQTAGR.H "sp|P13647|K2C5_HUMAN,tr|H0YI76|H0YI76_HUMAN,tr|H0YIN9|H0YIN9_HUMAN" 3 1193.5677 68.65 43040 7676 2 1193.565742 597.7911 "Keratin, type II cytoskeletal 5 OS=Homo sapiens OX=9606 GN=KRT5 PE=1 SV=3" 4.53 1883.7 - 5.35E+06 - - - -1.612 - 2.257 0.527 - 603.5 1 2 0 -0.0019 10 0 0 0 1.25E+08 1.82E+06 - - - 5.205 0.9996 221125_WJC_METTL3_EV_vs_WT_F04.07681.07681.2 0.00141 18-Sep R.VLQENNEGLR.A sp|Q96Q89|KI20B_HUMAN 1 1170.5993 1.59 43042 7681 2 1170.59826 586.3069 Kinesin-like protein KIF20B OS=Homo sapiens OX=9606 GN=KIF20B PE=1 SV=3 4.53 1884.3 - 250116 - - - -0.8884 - 1.739 0.382 - 314.9 1 2 0 -0.001 10 0 0 0 1.82E+07 1.15E+07 - - - 3.4066 0.9743 221125_WJC_METTL3_EV_vs_WT_F04.07683.07683.2 1.29 12-May K.EWTPAGK.A sp|O00203|AP3B1_HUMAN 1 787.3865 0.53 43044 7683 2 787.383447 394.7005 AP-3 complex subunit beta-1 OS=Homo sapiens OX=9606 GN=AP3B1 PE=1 SV=3 6.1 1884.6 - 378030 - - - -3.819 - 1.21 0.241 - 113.4 1 2 0 -0.003 7 0 0 0 1.45E+07 2.72E+07 - - - 1.4241 0.9859 221125_WJC_METTL3_EV_vs_WT_F04.07685.07685.2 0.0923 12-Jun R.GSFQVTR[166.11].A "sp|P51659|DHB4_HUMAN,tr|A0A2R8YD50|A0A2R8YD50_HUMAN,tr|E7ER27|E7ER27_HUMAN,tr|A0A2R8YF45|A0A2R8YF45_HUMAN,tr|E7EPL9|E7EPL9_HUMAN,tr|A0A804HKU2|A0A804HKU2_HUMAN,tr|A0A2R8YDT8|A0A2R8YDT8_HUMAN,tr|A0A804HK65|A0A804HK65_HUMAN" 8 803.4165 0.6 43045 7685 2 803.414816 402.7155 Peroxisomal multifunctional enzyme type 2 OS=Homo sapiens OX=9606 GN=HSD17B4 PE=1 SV=3 9.75 1884.8 - 2.10E+06 - - - -2.1234 - 1.346 0.134 - 153.2 1 2 0 -0.0017 7 0 0 0 4.50E+07 7.53E+07 - - - 0.9717 0.9997 221125_WJC_METTL3_EV_vs_WT_F04.07687.07687.2 0.000345 16-Sep K.SFQQSSLSR.D "sp|P43243|MATR3_HUMAN,tr|A0A1B0GX04|A0A1B0GX04_HUMAN,tr|D6RBS2|D6RBS2_HUMAN,tr|A8MXP9|A8MXP9_HUMAN,tr|D6R991|D6R991_HUMAN,tr|D6REK4|D6REK4_HUMAN,tr|D6R9F3|D6R9F3_HUMAN,tr|A0A0R4J2E8|A0A0R4J2E8_HUMAN,tr|D6RB45|D6RB45_HUMAN,tr|D6RCM3|D6RCM3_HUMAN,tr|D6R8Z5|D6R8Z5_HUMAN,tr|D6REM6|D6REM6_HUMAN" 12 1038.5094 1.25 43047 7687 2 1038.50841 520.262 Matrin-3 OS=Homo sapiens OX=9606 GN=MATR3 PE=1 SV=2 9.47 1885 - 3.03E+07 - - - -0.9754 - 1.62 0.475 - 299.4 1 2 0 -0.001 9 0 0 0 1.71E+09 1.36E+09 - - - 3.9447 0.9997 221125_WJC_METTL3_EV_vs_WT_F04.07688.07688.2 0.000744 14-Oct K.YQEELEDR.L "sp|Q9BUK6|MSTO1_HUMAN,tr|A0A3B3IUD2|A0A3B3IUD2_HUMAN" 2 1080.4724 14.22 43048 7688 2 1080.470861 541.2435 Protein misato homolog 1 OS=Homo sapiens OX=9606 GN=MSTO1 PE=1 SV=1 4 1885 - 3.31E+06 - - - -1.3948 - 1.718 0.45 - 299.3 1 2 0 -0.0015 8 0 0 0 4.96E+08 3.49E+07 - - - 3.9963 0.9949 221125_WJC_METTL3_EV_vs_WT_F04.07691.07691.2 0.0518 14-Aug K.EVEISHLK.A sp|Q15643|TRIPB_HUMAN 1 953.5182 1.21 43049 7691 2 953.518329 477.7664 Thyroid receptor-interacting protein 11 OS=Homo sapiens OX=9606 GN=TRIP11 PE=1 SV=3 5.4 1885.4 - 2.07E+06 - - - 0.1395 - 1.366 0.151 - 250.6 1 2 0 0.0001 8 0 0 0 4.27E+07 3.55E+07 - - - 1.0969 0.9971 221125_WJC_METTL3_EV_vs_WT_F04.07692.07692.2 0.125 12-Jun R.VEEIMEK.S "sp|O75688|PPM1B_HUMAN,tr|B8ZZF0|B8ZZF0_HUMAN,tr|A0A3B3IS24|A0A3B3IS24_HUMAN,tr|C9JIR6|C9JIR6_HUMAN" 4 876.4263 0.87 43050 7692 2 876.425673 439.2204 Protein phosphatase 1B OS=Homo sapiens OX=9606 GN=PPM1B PE=1 SV=1 4.25 1885.5 - 869858 - - - -0.6812 - 1.271 0.238 - 135.5 1 2 0 -0.0006 7 0 0 0 4.77E+07 5.48E+07 - - - 1.5585 0.9953 221125_WJC_METTL3_EV_vs_WT_F04.07698.07698.2 0.298 14-May R.EYENELAK.V sp|P15924|DESP_HUMAN 1 994.4607 36.41 43054 7698 2 994.459642 498.2376 Desmoplakin OS=Homo sapiens OX=9606 GN=DSP PE=1 SV=3 4.25 1886.2 - 6.84E+06 - - - -1.1051 - 1.288 0.205 - 105.8 1 2 0 -0.0011 8 0 0 0 2.35E+08 6.45E+06 - - - 1.3181 0.9652 221125_WJC_METTL3_EV_vs_WT_F04.07699.07699.2 1.02 14-Jul R.ELSEQIQR[166.11].A "sp|P15311|EZRI_HUMAN,tr|E7EQR4|E7EQR4_HUMAN" 2 1011.5224 0.88 43055 7699 2 1011.518585 506.7685 Ezrin OS=Homo sapiens OX=9606 GN=EZR PE=1 SV=4 4.53 1886.3 - 1.01E+06 - - - -3.815 - 1.552 0.112 - 277.5 1 2 0 -0.0039 8 0 0 0 2.66E+07 3.01E+07 - - - 1.1927 0.9982 221125_WJC_METTL3_EV_vs_WT_F04.07700.07700.2 0.808 14-Jun R.NTNPNFVR[166.11].C "sp|P35580|MYH10_HUMAN,sp|P35579|MYH9_HUMAN" 2 970.486 0.92 43056 7700 2 970.485925 486.2503 Myosin-10 OS=Homo sapiens OX=9606 GN=MYH10 PE=1 SV=3 9.75 1886.4 - 3.45E+06 - - - -0.0752 - 1.455 0.228 - 184.9 1 2 0 -0.0001 8 0 0 0 2.46E+08 2.67E+08 - - - 1.856 0.9628 221125_WJC_METTL3_EV_vs_WT_F04.07702.07702.2 0.791 14-Aug R.ANITLSGK[136.11].K "sp|E9PRG8|CK098_HUMAN,tr|E9PLD3|E9PLD3_HUMAN,tr|A0A494BXY3|A0A494BXY3_HUMAN" 3 810.4691 0.55 43058 7702 2 810.465906 406.2418 Uncharacterized protein C11orf98 OS=Homo sapiens OX=9606 GN=C11orf98 PE=4 SV=2 8.8 1886.6 - 471811 - - - -3.9014 - 1.447 0.14 - 233.4 1 2 0 -0.0032 8 0 0 0 3.08E+07 5.58E+07 - - - 1.1884 0.9489 221125_WJC_METTL3_EV_vs_WT_F04.07707.07707.2 3.76 14-Jun R.TSIEVGVK.G sp|Q03052|PO3F1_HUMAN 1 831.4702 1403.86 43061 7707 2 831.468328 416.7424 "POU domain, class 3, transcription factor 1 OS=Homo sapiens OX=9606 GN=POU3F1 PE=2 SV=3" 5.66 1887.1 - 1.27E+06 - - - -2.231 - 1.114 0.104 - 138.6 1 2 0 -0.0019 8 0 0 0 6.55E+07 4.67E+04 - - - 0.1342 0.9969 221125_WJC_METTL3_EV_vs_WT_F04.07710.07710.2 0.11 16-Aug K.EILTNEESR.A "sp|Q9UKB3|DJC12_HUMAN,tr|S4R3E2|S4R3E2_HUMAN" 2 1089.5302 3.69 43064 7710 2 1089.530422 545.7724 DnaJ homolog subfamily C member 12 OS=Homo sapiens OX=9606 GN=DNAJC12 PE=1 SV=1 4.25 1887.3 - 1.07E+06 - - - 0.1872 - 1.548 0.157 - 236.2 1 2 0 0.0002 9 0 0 0 2.17E+07 5.87E+06 - - - 1.4647 0.9533 221125_WJC_METTL3_EV_vs_WT_F04.07711.07711.2 5.69 12-Jun R.TNLGILR.A "sp|Q5H9S7|DCA17_HUMAN,tr|F5H7W1|F5H7W1_HUMAN,tr|H7C1H3|H7C1H3_HUMAN" 3 785.4759 999 43065 7711 2 785.476357 393.7452 DDB1- and CUL4-associated factor 17 OS=Homo sapiens OX=9606 GN=DCAF17 PE=1 SV=1 9.41 1887.4 - 558958 - - - 0.5334 - 1.163 0.02 - 185.9 1 2 0 0.0004 7 0 0 0 1.21E+07 0.00E+00 - - - -0.333 0.9992 221125_WJC_METTL3_EV_vs_WT_F04.07714.07714.2 0.00934 22-Jun -.MYPESTTGSPAR.L "sp|Q13303|KCAB2_HUMAN,tr|K7EKU4|K7EKU4_HUMAN,tr|A0A590UJV4|A0A590UJV4_HUMAN,tr|A0A590UJJ4|A0A590UJJ4_HUMAN,tr|A0A590UJ15|A0A590UJ15_HUMAN,tr|Q5TG78|Q5TG78_HUMAN,tr|A0A590UJY1|A0A590UJY1_HUMAN,tr|A0A590UJ72|A0A590UJ72_HUMAN,tr|K7EIR5|K7EIR5_HUMAN,tr|A0A590UJK5|A0A590UJK5_HUMAN,tr|Q5TG84|Q5TG84_HUMAN,tr|A0A590UK89|A0A590UK89_HUMAN,tr|A0A5F9UN28|A0A5F9UN28_HUMAN,tr|A0A590UJU1|A0A590UJU1_HUMAN,tr|A0A590UJU4|A0A590UJU4_HUMAN,tr|A0A590UJI8|A0A590UJI8_HUMAN,tr|A0A590UJX9|A0A590UJX9_HUMAN" 17 1295.5816 1.65 43068 7714 2 1295.582771 648.7981 Voltage-gated potassium channel subunit beta-2 OS=Homo sapiens OX=9606 GN=KCNAB2 PE=1 SV=2 5.75 1887.8 - 164138 - - - 0.9031 - 1.157 0.451 - 126.9 1 2 0 0.0012 12 0 0 0 3.74E+06 2.26E+06 - - - 2.7554 0.9601 221125_WJC_METTL3_EV_vs_WT_F04.07718.07718.2 0.00242 14-Jun S.DNIQGITK[136.11].C "sp|Q99525|H4G_HUMAN,sp|P62805|H4_HUMAN" 2 895.4854 1.11 43070 7718 2 895.48487 448.75 Histone H4-like protein type G OS=Homo sapiens OX=9606 GN=H4C7 PE=1 SV=1 5.84 1888.3 - 933170 - - - -0.6432 - 1.49 0.341 - 186.4 1 1 0 -0.0006 8 0 0 0 5.28E+07 4.75E+07 - - - 2.7621 0.9959 221125_WJC_METTL3_EV_vs_WT_F04.07720.07720.2 0.0816 14-Jul R.ANITLSGK.K "sp|E9PRG8|CK098_HUMAN,tr|E9PLD3|E9PLD3_HUMAN,tr|A0A494BXY3|A0A494BXY3_HUMAN" 3 802.4549 0.55 43072 7720 2 802.453689 402.2347 Uncharacterized protein C11orf98 OS=Homo sapiens OX=9606 GN=C11orf98 PE=4 SV=2 8.8 1888.5 - 614592 - - - -1.4692 - 1.4 0.221 - 124.3 2 2 0 -0.0012 8 0 0 0 3.09E+07 5.56E+07 - - - 1.5533 0.9932 221125_WJC_METTL3_EV_vs_WT_F04.07725.07725.2 0.0144 18-Oct R.ILADPSDDTK.G "sp|P58107|EPIPL_HUMAN,tr|A0A075B730|A0A075B730_HUMAN" 2 1073.5241 999 43075 7725 2 1073.518856 537.7693 Epiplakin OS=Homo sapiens OX=9606 GN=EPPK1 PE=1 SV=3 3.93 1889.1 - 764874 - - - -4.8569 - 1.665 0.38 - 192.6 1 2 0 -0.0052 10 0 0 0 2.17E+07 0.00E+00 - - - 3.2691 0.9655 221125_WJC_METTL3_EV_vs_WT_F04.07730.07730.2 0.031 18-Sep L.IAAQATALNR.G "sp|Q8IY67|RAVR1_HUMAN,tr|E9PAU2|E9PAU2_HUMAN,tr|A0A087WZ13|A0A087WZ13_HUMAN" 3 1027.5774 0.78 43077 7730 2 1027.578677 514.796 Ribonucleoprotein PTB-binding 1 OS=Homo sapiens OX=9606 GN=RAVER1 PE=1 SV=1 9.75 1889.7 - 478030 - - - 1.2009 - 1.805 0.345 - 237.2 1 1 0 0.0012 10 0 0 0 2.50E+07 3.21E+07 - - - 3.2372 0.9998 221125_WJC_METTL3_EV_vs_WT_F04.07739.07739.2 0.000604 20-Aug K.MEESAEYEAAR.H sp|Q86TJ2|TAD2B_HUMAN 1 1284.5292 1.38 43080 7739 2 1284.529168 643.2719 Transcriptional adapter 2-beta OS=Homo sapiens OX=9606 GN=TADA2B PE=1 SV=2 4.09 1890.9 - 92731.5 - - - -0.049 - 1.838 0.505 - 161.7 1 2 0 -0.0001 11 0 0 0 8.08E+06 5.86E+06 - - - 4.4175 0.9969 221125_WJC_METTL3_EV_vs_WT_F04.07743.07743.2 0.0291 22-Apr -.MYPESTTGSPAR[166.11].L "sp|Q13303|KCAB2_HUMAN,tr|K7EKU4|K7EKU4_HUMAN,tr|A0A590UJV4|A0A590UJV4_HUMAN,tr|A0A590UJJ4|A0A590UJJ4_HUMAN,tr|A0A590UJ15|A0A590UJ15_HUMAN,tr|Q5TG78|Q5TG78_HUMAN,tr|A0A590UJY1|A0A590UJY1_HUMAN,tr|A0A590UJ72|A0A590UJ72_HUMAN,tr|K7EIR5|K7EIR5_HUMAN,tr|A0A590UJK5|A0A590UJK5_HUMAN,tr|Q5TG84|Q5TG84_HUMAN,tr|A0A590UK89|A0A590UK89_HUMAN,tr|A0A5F9UN28|A0A5F9UN28_HUMAN,tr|A0A590UJU1|A0A590UJU1_HUMAN,tr|A0A590UJU4|A0A590UJU4_HUMAN,tr|A0A590UJI8|A0A590UJI8_HUMAN,tr|A0A590UJX9|A0A590UJX9_HUMAN" 17 1305.5899 1.85 43082 7743 2 1305.590248 653.8022 Voltage-gated potassium channel subunit beta-2 OS=Homo sapiens OX=9606 GN=KCNAB2 PE=1 SV=2 5.75 1891.4 - 61678.6 - - - 0.2888 - 0.938 0.352 - 35.3 1 2 0 0.0004 12 0 0 0 7.61E+06 4.10E+06 - - - 1.4723 0.9977 221125_WJC_METTL3_EV_vs_WT_F04.07746.07746.2 0.056 16-Aug R.VISVSTSER[166.11].T sp|Q6P2E9|EDC4_HUMAN 1 986.5272 1.75 43083 7746 2 986.527699 494.2709 Enhancer of mRNA-decapping protein 4 OS=Homo sapiens OX=9606 GN=EDC4 PE=1 SV=1 5.97 1891.8 - 1.66E+06 - - - 0.5109 - 1.342 0.252 - 169 1 2 0 0.0005 9 0 0 0 7.54E+07 4.31E+07 - - - 1.7531 0.9982 221125_WJC_METTL3_EV_vs_WT_F04.07747.07747.2 0.0919 14-Jul K.VVTVHLEK[136.11].L sp|Q9Y266|NUDC_HUMAN 1 931.5582 1.57 43084 7747 2 931.558397 466.7864 Nuclear migration protein nudC OS=Homo sapiens OX=9606 GN=NUDC PE=1 SV=1 6.72 1891.8 - 1.92E+06 - - - 0.1932 - 1.379 0.256 - 135.9 1 2 0 0.0002 8 0 0 0 9.95E+07 6.32E+07 - - - 1.901 0.9984 221125_WJC_METTL3_EV_vs_WT_F04.07748.07748.2 0.0382 12-Jun K.YEITEQR[166.11].K sp|Q02878|RL6_HUMAN 1 947.4588 0.98 43085 7748 2 947.459422 474.7367 60S ribosomal protein L6 OS=Homo sapiens OX=9606 GN=RPL6 PE=1 SV=3 4.53 1891.9 - 1.96E+06 - - - 0.6765 - 1.359 0.284 - 122.1 1 2 0 0.0006 7 0 0 0 6.09E+07 6.24E+07 - - - 2.1104 0.998 221125_WJC_METTL3_EV_vs_WT_F04.07749.07749.2 0.106 12-Jun K.YEITEQR.K sp|Q02878|RL6_HUMAN 1 937.4505 0.97 43086 7749 2 937.451511 469.7325 60S ribosomal protein L6 OS=Homo sapiens OX=9606 GN=RPL6 PE=1 SV=3 4.53 1891.9 - 1.85E+06 - - - 1.0667 - 1.445 0.25 - 147.8 1 2 0 0.001 7 0 0 0 6.06E+07 6.24E+07 - - - 2.0536 0.9997 221125_WJC_METTL3_EV_vs_WT_F04.07751.07751.2 0.00804 20-Aug K.MEESAEYEAAR[166.11].H sp|Q86TJ2|TAD2B_HUMAN 1 1294.5375 1.38 43088 7751 2 1294.535821 648.276 Transcriptional adapter 2-beta OS=Homo sapiens OX=9606 GN=TADA2B PE=1 SV=2 4.09 1892.2 - 124494 - - - -1.2978 - 1.624 0.501 - 205.5 1 2 0 -0.0017 11 0 0 0 8.08E+06 5.86E+06 - - - 4.0526 0.9999 221125_WJC_METTL3_EV_vs_WT_F04.07754.07754.2 0.000605 18-Nov R.ITESEEVVSR.E "sp|P02545|LMNA_HUMAN,tr|A0A6Q8PF80|A0A6Q8PF80_HUMAN,tr|A0A804HL68|A0A804HL68_HUMAN,tr|A0A6Q8PFM1|A0A6Q8PFM1_HUMAN,tr|A0A6Q8PF59|A0A6Q8PF59_HUMAN,tr|A0A6Q8PFJ0|A0A6Q8PFJ0_HUMAN,tr|A0A6Q8PHQ9|A0A6Q8PHQ9_HUMAN,tr|A0A6Q8PGH0|A0A6Q8PGH0_HUMAN,tr|Q3BDU5|Q3BDU5_HUMAN" 9 1147.5721 1.62 43089 7754 2 1147.572488 574.7933 Prelamin-A\C OS=Homo sapiens OX=9606 GN=LMNA PE=1 SV=1 4.25 1892.6 - 4.16E+06 - - - 0.3538 - 2.405 0.514 - 475.8 1 2 0 0.0004 10 0 0 0 1.06E+08 6.56E+07 - - - 5.2868 0.9747 221125_WJC_METTL3_EV_vs_WT_F04.07755.07755.2 1.57 14-Jun R.ELALGSNK[136.11].L "sp|P13489|RINI_HUMAN,tr|H0YCR7|H0YCR7_HUMAN" 2 838.464 1.19 43090 7755 2 838.463689 420.2393 Ribonuclease inhibitor OS=Homo sapiens OX=9606 GN=RNH1 PE=1 SV=2 6.1 1892.7 - 490219 - - - -0.3494 - 1.28 0.059 - 110.4 3 2 0 -0.0003 8 0 0 0 1.63E+07 1.37E+07 - - - 0.0081 0.9998 221125_WJC_METTL3_EV_vs_WT_F04.07756.07756.2 0.00866 16-Oct K.NLTQDEMQR.M sp|Q14152|EIF3A_HUMAN 1 1133.5135 2.86 43091 7756 2 1133.514619 567.764 Eukaryotic translation initiation factor 3 subunit A OS=Homo sapiens OX=9606 GN=EIF3A PE=1 SV=1 4.37 1892.8 - 805942 - - - 0.9678 - 2.022 0.459 - 420.5 1 2 0 0.0011 9 0 0 0 8.00E+07 2.80E+07 - - - 4.4678 0.9983 221125_WJC_METTL3_EV_vs_WT_F04.07757.07757.2 0.267 12-Oct K.HIIEGLK[136.11].A "sp|Q13303|KCAB2_HUMAN,sp|Q14722|KCAB1_HUMAN,tr|A0A590UJJ4|A0A590UJJ4_HUMAN,tr|A0A590UJY1|A0A590UJY1_HUMAN,tr|C9JQ60|C9JQ60_HUMAN,tr|Q5TG84|Q5TG84_HUMAN,tr|Q5TG81|Q5TG81_HUMAN,tr|A0A5F9UN28|A0A5F9UN28_HUMAN,tr|A0A590UJB6|A0A590UJB6_HUMAN" 9 816.4949 1.91 43092 7757 2 816.494916 409.2547 Voltage-gated potassium channel subunit beta-2 OS=Homo sapiens OX=9606 GN=KCNAB2 PE=1 SV=2 6.75 1893 - 266524 - - - 0.0331 - 1.652 0.174 - 372.6 1 2 0 0 7 0 0 0 1.20E+08 6.26E+07 - - - 1.9167 0.9947 221125_WJC_METTL3_EV_vs_WT_F04.07759.07759.2 0.0589 22-Jul K.LQEAPSAASQMK.R "sp|Q5JSZ5|PRC2B_HUMAN,tr|A0A804HJR4|A0A804HJR4_HUMAN" 2 1259.618 4.59 43094 7759 2 1259.62126 630.8163 Protein PRRC2B OS=Homo sapiens OX=9606 GN=PRRC2B PE=1 SV=2 6 1893.2 - 160920 - - - 2.5984 - 1.614 0.23 - 144.7 1 2 0 0.0033 12 0 0 0 4.57E+06 9.96E+05 - - - 1.9983 0.9996 221125_WJC_METTL3_EV_vs_WT_F04.07763.07763.2 0.000949 14-Oct K.MVINHLEK[136.11].L "sp|P50990|TCPQ_HUMAN,tr|H7C4C8|H7C4C8_HUMAN" 2 990.5412 0.32 43096 7763 2 990.542897 496.2779 T-complex protein 1 subunit theta OS=Homo sapiens OX=9606 GN=CCT8 PE=1 SV=4 6.5 1893.7 - 2.98E+06 - - - 1.7263 - 1.802 0.431 - 308.8 1 2 0 0.0017 8 0 0 0 1.22E+08 3.83E+08 - - - 3.9999 0.982 221125_WJC_METTL3_EV_vs_WT_F04.07764.07764.2 0.000405 16-Jul R.FQEDQEMAR[166.11].D "sp|Q9BQ70|TCF25_HUMAN,tr|H3BTU3|H3BTU3_HUMAN,tr|Q9H384|Q9H384_HUMAN,tr|H3BSS3|H3BSS3_HUMAN,tr|H3BQ53|H3BQ53_HUMAN" 5 1162.4952 0.89 43097 7764 2 1162.502951 582.2549 Transcription factor 25 OS=Homo sapiens OX=9606 GN=TCF25 PE=1 SV=1 4.14 1893.8 - 155899 - - - 6.6306 - 1.459 0.456 - 133.1 1 2 0 0.0077 9 0 0 0 3.79E+06 4.28E+06 - - - 3.4994 0.9998 221125_WJC_METTL3_EV_vs_WT_F04.07769.07769.2 0.00126 20-Aug R.VDQGAATALSR[166.11].K sp|Q8TBA6|GOGA5_HUMAN 1 1097.5705 1.33 43100 7769 2 1097.571435 549.7925 Golgin subfamily A member 5 OS=Homo sapiens OX=9606 GN=GOLGA5 PE=1 SV=3 5.81 1894.4 - 810820 - - - 0.892 - 2.114 0.463 - 285.5 1 2 0 0.001 11 0 0 0 6.52E+07 4.92E+07 - - - 4.4855 0.999 221125_WJC_METTL3_EV_vs_WT_F04.07772.07772.2 0.0758 22-Jul R.GLVSDGTSPGER.W sp|Q9NRF2|SH2B1_HUMAN 1 1173.5626 0.61 43103 7772 2 1173.565487 587.7886 SH2B adapter protein 1 OS=Homo sapiens OX=9606 GN=SH2B1 PE=1 SV=3 4.37 1894.7 - 325864 - - - 2.4771 - 1.866 0.388 - 143.2 1 2 0 0.0029 12 0 0 0 1.17E+07 1.91E+07 - - - 3.5472 0.9759 221125_WJC_METTL3_EV_vs_WT_F04.07778.07778.2 0.647 14-Aug K.MVINHLEK.L "sp|P50990|TCPQ_HUMAN,tr|H7C4C8|H7C4C8_HUMAN" 2 982.527 0.32 43107 7778 2 982.529049 492.2708 T-complex protein 1 subunit theta OS=Homo sapiens OX=9606 GN=CCT8 PE=1 SV=4 6.5 1895.3 - 1.45E+06 - - - 2.0987 - 1.192 0.143 - 179.8 1 2 0 0.0021 8 0 0 0 1.22E+08 3.82E+08 - - - 0.6262 0.999 221125_WJC_METTL3_EV_vs_WT_F04.07779.07779.2 0.0294 14-Aug K.STVSLDPK.D sp|O43172|PRP4_HUMAN 1 845.4494 2.9 43108 7779 2 845.450382 423.732 U4\U6 small nuclear ribonucleoprotein Prp4 OS=Homo sapiens OX=9606 GN=PRPF4 PE=1 SV=2 5.55 1895.4 - 1.37E+06 - - - 1.1047 - 1.606 0.3 - 233.7 1 2 0 0.0009 8 0 0 0 9.10E+08 3.14E+08 - - - 2.6853 0.9993 221125_WJC_METTL3_EV_vs_WT_F04.07780.07780.2 0.192 12-Sep K.HIIEGLK.A "sp|Q13303|KCAB2_HUMAN,sp|Q14722|KCAB1_HUMAN,tr|A0A590UJJ4|A0A590UJJ4_HUMAN,tr|A0A590UJY1|A0A590UJY1_HUMAN,tr|C9JQ60|C9JQ60_HUMAN,tr|Q5TG84|Q5TG84_HUMAN,tr|Q5TG81|Q5TG81_HUMAN,tr|A0A5F9UN28|A0A5F9UN28_HUMAN,tr|A0A590UJB6|A0A590UJB6_HUMAN" 9 808.4807 1.85 43109 7780 2 808.480864 405.2476 Voltage-gated potassium channel subunit beta-2 OS=Homo sapiens OX=9606 GN=KCNAB2 PE=1 SV=2 6.75 1895.5 - 1.34E+06 - - - 0.2165 - 1.884 0.226 - 304.1 1 2 0 0.0002 7 0 0 0 1.21E+08 6.52E+07 - - - 2.7171 0.9994 221125_WJC_METTL3_EV_vs_WT_F04.07784.07784.2 0.0113 14-Jul R.NGPEFEAR.L sp|Q15459|SF3A1_HUMAN 1 918.4195 1.07 43112 7784 2 918.419975 460.217 Splicing factor 3A subunit 1 OS=Homo sapiens OX=9606 GN=SF3A1 PE=1 SV=1 4.53 1895.9 - 2.59E+06 - - - 0.4682 - 1.458 0.366 - 254.9 1 2 0 0.0004 8 0 0 0 8.66E+07 8.10E+07 - - - 2.8814 0.9997 221125_WJC_METTL3_EV_vs_WT_F04.07786.07786.2 0.000545 14-Aug R.NGPEFEAR[166.11].L sp|Q15459|SF3A1_HUMAN 1 928.4278 1.15 43113 7786 2 928.428476 465.2212 Splicing factor 3A subunit 1 OS=Homo sapiens OX=9606 GN=SF3A1 PE=1 SV=1 4.53 1896.2 - 2.86E+06 - - - 0.712 - 1.621 0.458 - 315.3 1 2 0 0.0007 8 0 0 0 9.37E+07 8.14E+07 - - - 3.8804 0.9999 221125_WJC_METTL3_EV_vs_WT_F04.07789.07789.2 0.000801 20-Oct R.VELAEEDDGEK.L "sp|Q9H4A3|WNK1_HUMAN,tr|F5GWT4|F5GWT4_HUMAN" 2 1232.5408 2.13 43114 7789 2 1232.541052 617.2777 Serine\threonine-protein kinase WNK1 OS=Homo sapiens OX=9606 GN=WNK1 PE=1 SV=2 3.77 1896.6 - 154823 - - - 0.1704 - 1.904 0.533 - 275.4 1 2 0 0.0002 11 0 0 0 1.23E+07 5.77E+06 - - - 4.7197 0.9987 221125_WJC_METTL3_EV_vs_WT_F04.07790.07790.2 6.11E-05 20-Sep R.VELAEEDDGEK[136.11].L "sp|Q9H4A3|WNK1_HUMAN,tr|F5GWT4|F5GWT4_HUMAN" 2 1240.555 2.13 43115 7790 2 1240.549692 621.2848 Serine\threonine-protein kinase WNK1 OS=Homo sapiens OX=9606 GN=WNK1 PE=1 SV=2 3.77 1896.7 - 114583 - - - -4.3126 - 1.927 0.572 - 297.5 1 2 0 -0.0053 11 0 0 0 1.23E+07 5.77E+06 - - - 5.0387 0.9922 221125_WJC_METTL3_EV_vs_WT_F04.07795.07795.2 0.331 12-Aug R.RPLQVLR.A sp|P01036|CYTS_HUMAN 1 880.5607 1.96 43117 7795 2 880.560313 441.2876 Cystatin-S OS=Homo sapiens OX=9606 GN=CST4 PE=1 SV=3 12 1897.4 - 567658 - - - -0.4054 - 1.629 0.029 - 184 1 2 0 -0.0004 7 0 0 0 2.24E+07 1.15E+07 - - - 0.8012 0.9506 221125_WJC_METTL3_EV_vs_WT_F04.07797.07797.2 8.6 12-May R.LEDELNR.A "sp|P15924|DESP_HUMAN,sp|Q9UHC9|NPCL1_HUMAN,sp|O15118|NPC1_HUMAN,tr|A0A0C4DFX6|A0A0C4DFX6_HUMAN,tr|A0A0C4DGG6|A0A0C4DGG6_HUMAN,tr|K7EQ23|K7EQ23_HUMAN" 6 887.4349 19.29 43119 7797 2 887.435578 444.7247 Desmoplakin OS=Homo sapiens OX=9606 GN=DSP PE=1 SV=3 4.14 1897.6 - 757339 - - - 0.8079 - 1.228 0 - 72.2 1 2 0 0.0007 7 0 0 0 1.47E+07 7.63E+05 - - - -0.3084 0.9997 221125_WJC_METTL3_EV_vs_WT_F04.07798.07798.2 0.000246 22-Jul R.LC[160.03]TSATESEVAR.G sp|P31930|QCR1_HUMAN 1 1322.6136 1.39 43120 7798 2 1322.614333 662.3141 "Cytochrome b-c1 complex subunit 1, mitochondrial OS=Homo sapiens OX=9606 GN=UQCRC1 PE=1 SV=3" 4.53 1897.7 - 96909.6 - - - 0.5315 - 1.673 0.468 - 117.7 1 2 0 0.0007 12 0 0 0 1.44E+07 1.04E+07 - - - 3.8515 0.9845 221125_WJC_METTL3_EV_vs_WT_F04.07801.07801.2 0.0456 14-Jul R.EIAENITK.H sp|P54136|SYRC_HUMAN 1 916.4866 1.18 43121 7801 2 916.487695 459.2506 "Arginine--tRNA ligase, cytoplasmic OS=Homo sapiens OX=9606 GN=RARS1 PE=1 SV=2" 4.53 1898.1 - 3.75E+06 - - - 1.2362 - 1.301 0.102 - 205.2 1 2 0 0.0011 8 0 0 0 1.57E+08 1.33E+08 - - - 0.5876 0.9985 221125_WJC_METTL3_EV_vs_WT_F04.07802.07802.2 0.299 12-Aug R.QLDQLSR[166.11].L "sp|Q6P3W7|SCYL2_HUMAN,tr|F8VSC5|F8VSC5_HUMAN,tr|A0A0U1RQQ9|A0A0U1RQQ9_HUMAN" 3 868.4642 1.7 43122 7802 2 868.464227 435.2394 SCY1-like protein 2 OS=Homo sapiens OX=9606 GN=SCYL2 PE=1 SV=1 5.84 1898.2 - 1.28E+06 - - - 0.0311 - 1.58 0.209 - 406.8 1 2 0 0 7 0 0 0 7.19E+07 4.23E+07 - - - 2.034 0.9947 221125_WJC_METTL3_EV_vs_WT_F04.07803.07803.2 0.254 14-Jun R.EIAENITK[136.11].H sp|P54136|SYRC_HUMAN 1 924.5008 1.19 43123 7803 2 924.501337 463.2577 "Arginine--tRNA ligase, cytoplasmic OS=Homo sapiens OX=9606 GN=RARS1 PE=1 SV=2" 4.53 1898.3 - 3.72E+06 - - - 0.622 - 1.298 0.179 - 139.8 1 2 0 0.0006 8 0 0 0 1.54E+08 1.29E+08 - - - 1.1495 0.9998 221125_WJC_METTL3_EV_vs_WT_F04.07805.07805.2 0.000395 18-Nov K.VVQSLEQTAR[166.11].E "sp|Q15631|TSN_HUMAN,tr|A0A0J9YVW2|A0A0J9YVW2_HUMAN,tr|E9PGT1|E9PGT1_HUMAN,tr|H7C1D4|H7C1D4_HUMAN" 4 1139.6174 0.68 43125 7805 2 1139.618752 570.816 Translin OS=Homo sapiens OX=9606 GN=TSN PE=1 SV=1 5.97 1898.5 - 234951 - - - 1.1802 - 2.197 0.421 - 492 1 2 0 0.0013 10 0 0 0 6.38E+06 9.44E+06 - - - 4.3471 0.9999 221125_WJC_METTL3_EV_vs_WT_F04.07808.07808.2 1.12E-05 20-Nov K.AAIISAEGDSK[136.11].A "sp|P35232|PHB_HUMAN,tr|C9JZ20|C9JZ20_HUMAN,tr|C9JW96|C9JW96_HUMAN" 3 1068.5543 1.45 43127 7808 2 1068.554595 535.2844 Prohibitin OS=Homo sapiens OX=9606 GN=PHB PE=1 SV=1 4.37 1898.9 - 1.17E+07 - - - 0.3191 - 2.552 0.491 - 320.1 1 2 0 0.0003 11 0 0 0 4.33E+08 2.99E+08 - - - 5.2019 0.8059 221125_WJC_METTL3_EV_vs_WT_F04.07810.07810.2 1.54 12-Jul H.AEEILEK.H "sp|P54852|EMP3_HUMAN,sp|P62913|RL11_HUMAN,tr|Q5VVC8|Q5VVC8_HUMAN,tr|M0QXS0|M0QXS0_HUMAN" 4 830.4385 1.41 43129 7810 2 830.438002 416.2266 Epithelial membrane protein 3 OS=Homo sapiens OX=9606 GN=EMP3 PE=1 SV=1 4.25 1899.1 - 1.37E+06 - - - -0.6587 - 1.484 0.138 - 266 1 1 0 -0.0005 7 0 0 0 5.79E+07 4.09E+07 - - - 1.3109 0.997 221125_WJC_METTL3_EV_vs_WT_F04.07811.07811.2 1.62 12-Jul R.TTWAEER[166.11].K sp|Q9BX40|LS14B_HUMAN 1 901.4169 0.77 43130 7811 2 901.41718 451.7157 Protein LSM14 homolog B OS=Homo sapiens OX=9606 GN=LSM14B PE=1 SV=1 4.53 1899.2 - 842610 - - - 0.2929 - 1.421 0.182 - 315.7 1 2 0 0.0003 7 0 0 0 3.81E+07 4.93E+07 - - - 1.4985 0.9807 221125_WJC_METTL3_EV_vs_WT_F04.07812.07812.2 2.68 16-Jun R.KAFDMISQR[166.11].S "sp|O14908|GIPC1_HUMAN,tr|K7ESN1|K7ESN1_HUMAN" 2 1104.5625 - 43131 7812 2 1104.561983 553.2885 PDZ domain-containing protein GIPC1 OS=Homo sapiens OX=9606 GN=GIPC1 PE=1 SV=2 8.75 1899.3 - 366685 - - - -0.4988 - 1.393 0.074 - 104.5 6 2 0 -0.0006 9 0 0 0 - - - - - 0.1987 0.9997 221125_WJC_METTL3_EV_vs_WT_F04.07813.07813.2 5.06E-06 22-Sep R.LC[160.03]TSATESEVAR[166.11].G sp|P31930|QCR1_HUMAN 1 1332.6219 1.39 43132 7813 2 1332.619724 667.3182 "Cytochrome b-c1 complex subunit 1, mitochondrial OS=Homo sapiens OX=9606 GN=UQCRC1 PE=1 SV=3" 4.53 1899.4 - 223032 - - - -1.6329 - 1.627 0.531 - 239.1 1 2 0 -0.0022 12 0 0 0 1.44E+07 1.04E+07 - - - 4.243 0.9973 221125_WJC_METTL3_EV_vs_WT_F04.07825.07825.2 0.0737 16-Jul R.YR[166.11]PGTVALR[166.11].E "sp|Q5TEC6|H3PS2_HUMAN,sp|Q16695|H31T_HUMAN,sp|P84243|H33_HUMAN,sp|Q6NXT2|H3C_HUMAN,sp|Q71DI3|H32_HUMAN,sp|P68431|H31_HUMAN,tr|B4DEB1|B4DEB1_HUMAN,tr|K7EK07|K7EK07_HUMAN,tr|K7ES00|K7ES00_HUMAN,tr|K7EP01|K7EP01_HUMAN,tr|K7EMV3|K7EMV3_HUMAN,tr|A0A590UJJ6|A0A590UJJ6_HUMAN" 12 1051.6042 0.96 43140 7825 2 1051.604042 526.8094 Histone HIST2H3PS2 OS=Homo sapiens OX=9606 GN=H3-2 PE=1 SV=1 10.84 1900.9 - 3.02E+06 - - - -0.1056 - 1.336 0.226 - 105.3 1 2 0 -0.0001 9 0 0 0 1.04E+09 1.09E+09 - - - 1.5483 0.9996 221125_WJC_METTL3_EV_vs_WT_F04.07826.07826.2 0.0146 16-Sep K.IGDTSVSYK.Y sp|P20700|LMNB1_HUMAN 1 968.4815 1.16 43141 7826 2 968.481929 485.248 Lamin-B1 OS=Homo sapiens OX=9606 GN=LMNB1 PE=1 SV=2 5.83 1901 - 1.91E+06 - - - 0.4677 - 1.677 0.396 - 165.1 1 2 0 0.0005 9 0 0 0 1.99E+08 1.72E+08 - - - 3.4614 0.9999 221125_WJC_METTL3_EV_vs_WT_F04.07829.07829.2 8.10E-05 20-Nov R.VDQGAATALSR.K sp|Q8TBA6|GOGA5_HUMAN 1 1087.5622 1.27 43142 7829 2 1087.562115 544.7884 Golgin subfamily A member 5 OS=Homo sapiens OX=9606 GN=GOLGA5 PE=1 SV=3 5.81 1901.4 - 1.77E+06 - - - -0.0653 - 2.393 0.534 - 563.4 1 2 0 -0.0001 11 0 0 0 6.51E+07 5.12E+07 - - - 5.3455 0.9986 221125_WJC_METTL3_EV_vs_WT_F04.07833.07833.2 0.0015 16-Jul R.AEPLNSVAH.- "sp|O95777|LSM8_HUMAN,tr|C9JIZ0|C9JIZ0_HUMAN" 2 936.4665 - 43144 7833 2 936.464163 469.2405 U6 snRNA-associated Sm-like protein LSm8 OS=Homo sapiens OX=9606 GN=LSM8 PE=1 SV=3 5.24 1901.8 - 847789 - - - -2.4902 - 1.491 0.4 - 101.9 1 2 0 -0.0023 9 0 0 0 - - - - - 3.1503 0.9951 221125_WJC_METTL3_EV_vs_WT_F04.07843.07843.2 0.000403 20-May R.MVTGDNINTAR.A "sp|Q01814|AT2B2_HUMAN,sp|P20020|AT2B1_HUMAN,sp|Q16720|AT2B3_HUMAN,sp|P23634|AT2B4_HUMAN,tr|A0A804HKZ0|A0A804HKZ0_HUMAN,tr|E7ERY9|E7ERY9_HUMAN,tr|A0A2R8Y4R4|A0A2R8Y4R4_HUMAN,tr|A0A2U3TZI3|A0A2U3TZI3_HUMAN,tr|A0A2U3U055|A0A2U3U055_HUMAN" 9 1190.5714 0.86 43152 7843 2 1190.566835 596.293 Plasma membrane calcium-transporting ATPase 2 OS=Homo sapiens OX=9606 GN=ATP2B2 PE=1 SV=2 5.59 1903 - 256058 - - - -3.8099 - 1.365 0.399 - 59.6 1 2 0 -0.0045 11 0 0 0 9.00E+06 1.05E+07 - - - 2.8283 0.9994 221125_WJC_METTL3_EV_vs_WT_F04.07847.07847.2 0.00311 14-Jun K.ESFDGSVR.A "sp|P19338|NUCL_HUMAN,tr|A0A7I2V699|A0A7I2V699_HUMAN,tr|A0A7I2V2U7|A0A7I2V2U7_HUMAN,tr|A0A7I2V3F3|A0A7I2V3F3_HUMAN,tr|A0A7I2V428|A0A7I2V428_HUMAN,tr|H7BY16|H7BY16_HUMAN,tr|A0A7I2V5M5|A0A7I2V5M5_HUMAN,tr|C9JLB1|C9JLB1_HUMAN" 8 895.4036 0.97 43155 7847 2 895.404017 448.7091 Nucleolin OS=Homo sapiens OX=9606 GN=NCL PE=1 SV=3 4.37 1903.4 - 4.12E+06 - - - 0.5104 - 1.317 0.41 - 93.7 1 2 0 0.0005 8 0 0 0 2.46E+08 2.54E+08 - - - 2.8996 0.9692 221125_WJC_METTL3_EV_vs_WT_F04.07849.07849.2 0.0437 16-Sep A.LEC[160.03]YSC[160.03]VQK.A sp|O95274|LYPD3_HUMAN 1 1185.5158 158.99 43156 7849 2 1185.51669 593.7652 Ly6\PLAUR domain-containing protein 3 OS=Homo sapiens OX=9606 GN=LYPD3 PE=1 SV=2 5.99 1903.6 - 487467 - - - 0.7254 - 1.6 0.37 - 196.6 1 1 0 0.0009 9 0 0 0 1.43E+07 9.00E+04 - - - 3.1333 0.9971 221125_WJC_METTL3_EV_vs_WT_F04.07851.07851.3 0.171 Oct-40 K.LVDNRPPALAK.F sp|Q92545|TM131_HUMAN 1 1192.6928 1.61 43157 7851 3 1192.692354 398.5715 Transmembrane protein 131 OS=Homo sapiens OX=9606 GN=TMEM131 PE=1 SV=3 8.75 1903.9 - 868510 - - - -0.3798 - 1.92 0.196 - 94.8 1 2 0 -0.0005 11 0 0 0 4.03E+07 2.51E+07 - - - 2.5782 0.9993 221125_WJC_METTL3_EV_vs_WT_F04.07858.07858.2 0.00257 18-Aug K.QFQSAPATVR.M "sp|Q9Y520|PRC2C_HUMAN,tr|E7EPN9|E7EPN9_HUMAN,tr|A0A2R8Y424|A0A2R8Y424_HUMAN,tr|H7C5N8|H7C5N8_HUMAN,tr|A0A2R8Y7F4|A0A2R8Y7F4_HUMAN,tr|A0A2R8YET2|A0A2R8YET2_HUMAN" 6 1103.5724 2.05 43161 7858 2 1103.571518 552.7935 Protein PRRC2C OS=Homo sapiens OX=9606 GN=PRRC2C PE=1 SV=4 9.75 1904.7 - 568484 - - - -0.7603 - 1.685 0.314 - 258.3 1 2 0 -0.0008 10 0 0 0 1.46E+07 7.14E+06 - - - 2.8163 0.9995 221125_WJC_METTL3_EV_vs_WT_F04.07862.07862.2 0.0761 18-Sep K.GSGTAEVELK.K "sp|P14618|KPYM_HUMAN,tr|H3BQ34|H3BQ34_HUMAN,tr|H3BTJ2|H3BTJ2_HUMAN,tr|A0A804F6T5|A0A804F6T5_HUMAN,tr|H3BT25|H3BT25_HUMAN,tr|H3BUW1|H3BUW1_HUMAN,tr|H3BTN5|H3BTN5_HUMAN,tr|A0A804F729|A0A804F729_HUMAN" 8 989.5029 0.07 43163 7862 2 989.50411 495.7587 Pyruvate kinase PKM OS=Homo sapiens OX=9606 GN=PKM PE=1 SV=4 4.53 1905.2 - 3.52E+06 - - - 1.1824 - 1.879 0.363 - 308.8 1 2 0 0.0012 10 0 0 0 9.68E+07 1.46E+09 - - - 3.4823 0.9965 221125_WJC_METTL3_EV_vs_WT_F04.07867.07867.2 0.271 16-Aug R.LQELDAASK[136.11].V sp|P09497|CLCB_HUMAN 1 981.5222 3.39 43166 7867 2 981.521181 491.7684 Clathrin light chain B OS=Homo sapiens OX=9606 GN=CLTB PE=1 SV=1 4.37 1905.7 - 1.15E+06 - - - -1.0647 - 1.726 0.123 - 153 1 2 0 -0.001 9 0 0 0 3.00E+08 8.86E+07 - - - 1.5282 0.9999 221125_WJC_METTL3_EV_vs_WT_F04.07868.07868.2 0.000108 24-Oct K.GPGEVAGTVTGQK[136.11].R "sp|Q86U44|MTA70_HUMAN,tr|F5H6D8|F5H6D8_HUMAN,tr|H0YFV6|H0YFV6_HUMAN,tr|B4DTN4|B4DTN4_HUMAN" 4 1207.6288 0 43167 7868 2 1207.630117 604.8217 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 6 1905.9 - 122654 - - - 1.0773 - 2.308 0.565 - 240.5 1 2 0 0.0013 13 0 0 0 5.58E+04 1.80E+07 - - - 5.3603 0.9986 221125_WJC_METTL3_EV_vs_WT_F04.07877.07877.2 0.0152 14-Aug R.GEAPFAQR.L "sp|Q9Y2R0|COA3_HUMAN,tr|K7EPV0|K7EPV0_HUMAN" 2 874.4297 0.04 43169 7877 2 874.428857 438.2221 "Cytochrome c oxidase assembly factor 3 homolog, mitochondrial OS=Homo sapiens OX=9606 GN=COA3 PE=1 SV=1" 6 1907.2 - 1.09E+06 - - - -0.9824 - 1.584 0.243 - 287.8 1 2 0 -0.0009 8 0 0 0 3.72E+07 9.79E+08 - - - 2.2227 0.999 221125_WJC_METTL3_EV_vs_WT_F04.07879.07879.2 0.149 20-Oct K.NTVVATGGYGR.T "sp|P31040|SDHA_HUMAN,tr|D6RFM5|D6RFM5_HUMAN,tr|A0A494C1T6|A0A494C1T6_HUMAN" 3 1093.5516 0.62 43171 7879 2 1093.550634 547.7831 "Succinate dehydrogenase [ubiquinone] flavoprotein subunit, mitochondrial OS=Homo sapiens OX=9606 GN=SDHA PE=1 SV=2" 8.75 1907.4 - 674384 - - - -0.9035 - 1.746 0.265 - 224.9 1 2 0 -0.001 11 0 0 0 5.60E+07 9.08E+07 - - - 2.5057 0.9931 221125_WJC_METTL3_EV_vs_WT_F04.07880.07880.2 0.115 14-Jul K.VSQQILEK[136.11].R "sp|Q9H845|ACAD9_HUMAN,tr|Q9H9W4|Q9H9W4_HUMAN,tr|H0Y8Z9|H0Y8Z9_HUMAN" 3 951.548 0.98 43172 7880 2 951.547372 476.7813 "Complex I assembly factor ACAD9, mitochondrial OS=Homo sapiens OX=9606 GN=ACAD9 PE=1 SV=1" 5.97 1907.6 - 500603 - - - -0.7083 - 1.085 0.24 - 127.9 2 2 0 -0.0007 8 0 0 0 3.81E+07 3.90E+07 - - - 0.925 0.999 221125_WJC_METTL3_EV_vs_WT_F04.07881.07881.2 0.00229 20-Apr R.MVTGDNINTAR[166.11].A "sp|Q01814|AT2B2_HUMAN,sp|P20020|AT2B1_HUMAN,sp|Q16720|AT2B3_HUMAN,sp|P23634|AT2B4_HUMAN,tr|A0A804HKZ0|A0A804HKZ0_HUMAN,tr|E7ERY9|E7ERY9_HUMAN,tr|A0A2R8Y4R4|A0A2R8Y4R4_HUMAN,tr|A0A2U3TZI3|A0A2U3TZI3_HUMAN,tr|A0A2U3U055|A0A2U3U055_HUMAN" 9 1200.5796 0.93 43173 7881 2 1200.579774 601.2971 Plasma membrane calcium-transporting ATPase 2 OS=Homo sapiens OX=9606 GN=ATP2B2 PE=1 SV=2 5.59 1907.7 - 206030 - - - 0.1108 - 1.226 0.418 - 38.7 5 2 0 0.0001 11 0 0 0 9.67E+06 1.05E+07 - - - 2.3673 0.9999 221125_WJC_METTL3_EV_vs_WT_F04.07884.07884.3 0.000533 Dec-36 K.VLVAQHDVYK.G "sp|P13804|ETFA_HUMAN,tr|H0YL12|H0YL12_HUMAN,tr|H0YKF0|H0YKF0_HUMAN,tr|H0YLU7|H0YLU7_HUMAN" 4 1170.6397 1.54 43174 7884 3 1170.640255 391.2205 "Electron transfer flavoprotein subunit alpha, mitochondrial OS=Homo sapiens OX=9606 GN=ETFA PE=1 SV=1" 6.71 1908.1 - 2.12E+06 - - - 0.4673 - 2.333 0.348 - 225.6 1 2 0 0.0005 10 0 0 0 1.35E+08 8.79E+07 - - - 4.8938 0.9997 221125_WJC_METTL3_EV_vs_WT_F04.07886.07886.3 0.00022 Nov-36 K.VLVAQHDVYK[136.11].G "sp|P13804|ETFA_HUMAN,tr|H0YL12|H0YL12_HUMAN,tr|H0YKF0|H0YKF0_HUMAN,tr|H0YLU7|H0YLU7_HUMAN" 4 1178.6539 1.54 43176 7886 3 1178.653456 393.8919 "Electron transfer flavoprotein subunit alpha, mitochondrial OS=Homo sapiens OX=9606 GN=ETFA PE=1 SV=1" 6.71 1908.3 - 1.56E+06 - - - -0.3835 - 1.891 0.35 - 180.8 1 2 0 -0.0005 10 0 0 0 1.35E+08 8.79E+07 - - - 4.3027 0.9527 221125_WJC_METTL3_EV_vs_WT_F04.07891.07891.2 4.81 12-Jul K.R[166.11]PFLEPK[136.11].K "sp|P78347|GTF2I_HUMAN,tr|A0A494C1K3|A0A494C1K3_HUMAN" 2 903.5297 2.61 43178 7891 2 903.528904 452.7721 General transcription factor II-I OS=Homo sapiens OX=9606 GN=GTF2I PE=1 SV=2 8.75 1908.9 - 6.17E+06 - - - -0.8898 - 1.169 0.02 - 299.3 1 2 0 -0.0008 7 0 0 0 1.49E+09 5.70E+08 - - - -0.3168 0.9998 221125_WJC_METTL3_EV_vs_WT_F04.07896.07896.2 3.90E-05 16-Aug R.AQYESLAAK.N "sp|Q16352|AINX_HUMAN,sp|P41219|PERI_HUMAN,tr|F8W835|F8W835_HUMAN" 3 979.4975 1.53 43181 7896 2 979.497509 490.756 Alpha-internexin OS=Homo sapiens OX=9606 GN=INA PE=1 SV=2 6.05 1909.6 - 2.33E+06 - - - 0.049 - 1.846 0.459 - 284 1 2 0 0 9 0 0 0 1.02E+08 6.70E+07 - - - 4.2047 0.9764 221125_WJC_METTL3_EV_vs_WT_F04.07897.07897.2 2.19 14-Jul K.VSQQILEK.R "sp|Q9H845|ACAD9_HUMAN,tr|Q9H9W4|Q9H9W4_HUMAN,tr|H0Y8Z9|H0Y8Z9_HUMAN" 3 943.5338 0.98 43182 7897 2 943.534708 472.7742 "Complex I assembly factor ACAD9, mitochondrial OS=Homo sapiens OX=9606 GN=ACAD9 PE=1 SV=1" 5.97 1909.6 - 954869 - - - 0.9136 - 1.26 0.063 - 136.2 1 2 0 0.0009 8 0 0 0 3.81E+07 3.90E+07 - - - 0.2031 0.9829 221125_WJC_METTL3_EV_vs_WT_F04.07903.07903.2 0.00113 13/24 L.LAALGGNSSPSAK[136.11].D sp|P05387|RLA2_HUMAN 1 1179.6339 2.18 43184 7903 2 1179.632151 590.8242 60S acidic ribosomal protein P2 OS=Homo sapiens OX=9606 GN=RPLP2 PE=1 SV=1 8.75 1910.4 - 506352 - - - -1.4835 - 2.243 0.413 - 537.6 1 1 0 -0.0018 13 0 0 0 2.84E+07 1.30E+07 - - - 4.1641 0.9472 221125_WJC_METTL3_EV_vs_WT_F04.07909.07909.2 0.028 14-Sep R.PRPLNTWK.L "sp|Q96PK6|RBM14_HUMAN,tr|B8ZZ74|B8ZZ74_HUMAN,tr|F8WDX3|F8WDX3_HUMAN,tr|A0A0A0MSL8|A0A0A0MSL8_HUMAN,tr|A0A0A6YYI9|A0A0A6YYI9_HUMAN" 5 1010.5661 1.76 43187 7909 2 1010.567339 506.2904 RNA-binding protein 14 OS=Homo sapiens OX=9606 GN=RBM14 PE=1 SV=2 11.01 1911.2 - 1.51E+06 - - - 1.1766 - 1.898 0.244 - 353.2 1 1 0 0.0012 8 0 0 0 5.49E+07 3.11E+07 - - - 2.7754 0.9997 221125_WJC_METTL3_EV_vs_WT_F04.07912.07912.2 0.00082 18-Aug K.NIGVDNPAAK[136.11].V "sp|P78371|TCPB_HUMAN,tr|F8VQ14|F8VQ14_HUMAN,tr|F5GWF6|F5GWF6_HUMAN" 3 1005.5335 0.61 43189 7912 2 1005.533512 503.774 T-complex protein 1 subunit beta OS=Homo sapiens OX=9606 GN=CCT2 PE=1 SV=4 5.84 1911.5 - 5.14E+06 - - - 0.0527 - 1.5 0.468 - 154.1 1 2 0 0.0001 10 0 0 0 1.73E+09 2.82E+09 - - - 3.6294 0.9979 221125_WJC_METTL3_EV_vs_WT_F04.07914.07914.2 0.0689 16-Jul R.SGVNSELVK.R "sp|P35659|DEK_HUMAN,tr|H0Y8X0|H0Y8X0_HUMAN,tr|H0Y993|H0Y993_HUMAN,tr|A0A494C028|A0A494C028_HUMAN,tr|D6RDA2|D6RDA2_HUMAN,tr|B4DFG0|B4DFG0_HUMAN" 6 931.4975 0.85 43190 7914 2 931.498284 466.756 Protein DEK OS=Homo sapiens OX=9606 GN=DEK PE=1 SV=1 5.72 1911.7 - 1.56E+06 - - - 0.8835 - 1.648 0.198 - 124.1 1 2 0 0.0008 9 0 0 0 5.27E+07 6.17E+07 - - - 1.9484 0.9991 221125_WJC_METTL3_EV_vs_WT_F04.07915.07915.2 0.0216 16-Aug R.EYEAEGIAK[136.11].D "sp|Q9HCC0|MCCB_HUMAN,tr|A0A804HJC1|A0A804HJC1_HUMAN,tr|A0A804HK37|A0A804HK37_HUMAN,tr|A0A804HJ24|A0A804HJ24_HUMAN,tr|A0A804HL02|A0A804HL02_HUMAN,tr|A0A804HKE8|A0A804HKE8_HUMAN,tr|A0A804HJ84|A0A804HJ84_HUMAN,tr|A0A804HLJ9|A0A804HLJ9_HUMAN,tr|A0A804HJL2|A0A804HJL2_HUMAN,tr|A0A804HKH3|A0A804HKH3_HUMAN,tr|A0A804HJ31|A0A804HJ31_HUMAN" 11 1016.4906 3.98 43191 7915 2 1016.490038 509.2526 "Methylcrotonoyl-CoA carboxylase beta chain, mitochondrial OS=Homo sapiens OX=9606 GN=MCCC2 PE=1 SV=1" 4.25 1911.7 - 922198 - - - -0.544 - 1.31 0.368 - 154.3 1 2 0 -0.0006 9 0 0 0 5.78E+07 1.45E+07 - - - 2.5401 0.9879 221125_WJC_METTL3_EV_vs_WT_F04.07916.07916.2 0.307 14-Jun K.GESGILGK[136.11].D sp|O43172|PRP4_HUMAN 1 767.4269 2.79 43192 7916 2 767.426108 384.7207 U4\U6 small nuclear ribonucleoprotein Prp4 OS=Homo sapiens OX=9606 GN=PRPF4 PE=1 SV=2 6 1911.9 - 425712 - - - -0.9916 - 1.238 0.125 - 139 1 2 0 -0.0008 8 0 0 0 2.95E+07 1.06E+07 - - - 0.6079 0.998 221125_WJC_METTL3_EV_vs_WT_F04.07921.07921.2 0.246 14-Sep K.VAAPNLSR[166.11].M sp|P78310|CXAR_HUMAN 1 836.4744 1.6 43195 7921 2 836.475516 419.2445 Coxsackievirus and adenovirus receptor OS=Homo sapiens OX=9606 GN=CXADR PE=1 SV=1 9.72 1912.5 - 372564 - - - 1.3688 - 1.796 0.187 - 345.4 1 2 0 0.0011 8 0 0 0 1.67E+07 1.05E+07 - - - 2.1879 0.9995 221125_WJC_METTL3_EV_vs_WT_F04.07922.07922.2 0.00262 16-Sep K.LTQEETNFK[136.11].S "sp|Q9NTJ3|SMC4_HUMAN,tr|E9PD53|E9PD53_HUMAN" 2 1116.5543 0.36 43196 7922 2 1116.553871 559.2844 Structural maintenance of chromosomes protein 4 OS=Homo sapiens OX=9606 GN=SMC4 PE=1 SV=2 4.53 1912.6 - 758562 - - - -0.343 - 1.6 0.355 - 177.1 1 2 0 -0.0004 9 0 0 0 1.10E+07 3.07E+07 - - - 3.0227 0.9883 221125_WJC_METTL3_EV_vs_WT_F04.07923.07923.2 0.0117 18-Jun K.TLEEPVSTEK.N "sp|Q99590|SCAFB_HUMAN,tr|F8VXG7|F8VXG7_HUMAN" 2 1131.5659 0.97 43197 7923 2 1131.567974 566.7902 Protein SCAF11 OS=Homo sapiens OX=9606 GN=SCAF11 PE=1 SV=2 4.25 1912.8 - 481432 - - - 1.8028 - 1.184 0.202 - 71.7 1 2 0 0.002 10 0 0 0 3.20E+07 3.29E+07 - - - 1.0038 0.9993 221125_WJC_METTL3_EV_vs_WT_F04.07926.07926.2 0.000244 18-Sep K.IINDNATYC[160.03]R[166.11].L "sp|O00567|NOP56_HUMAN,tr|A0A494C128|A0A494C128_HUMAN,tr|Q5JXT2|Q5JXT2_HUMAN" 3 1248.5796 0.89 43200 7926 2 1248.583606 625.2971 Nucleolar protein 56 OS=Homo sapiens OX=9606 GN=NOP56 PE=1 SV=4 5.83 1913.2 - 157617 - - - 3.1756 - 1.641 0.581 - 314.7 1 2 0 0.004 10 0 0 0 1.99E+07 2.23E+07 - - - 4.7136 0.9977 221125_WJC_METTL3_EV_vs_WT_F04.07930.07930.2 0.033 16-Aug K.LQEYNVGGK.V "sp|P46379|BAG6_HUMAN,tr|F6UR09|F6UR09_HUMAN,tr|A0A7I2V508|A0A7I2V508_HUMAN,tr|F6U1F2|F6U1F2_HUMAN,tr|F6U341|F6U341_HUMAN,tr|F6WML8|F6WML8_HUMAN,tr|A0A0G2JJM1|A0A0G2JJM1_HUMAN,tr|X6REW1|X6REW1_HUMAN,tr|A0A7I2V3H1|A0A7I2V3H1_HUMAN,tr|A0A7P0MQS5|A0A7P0MQS5_HUMAN,tr|F6XTU0|F6XTU0_HUMAN,tr|F6X9W3|F6X9W3_HUMAN,tr|F6VEM6|F6VEM6_HUMAN,tr|A0A0G2JJR8|A0A0G2JJR8_HUMAN,tr|F6S6P2|F6S6P2_HUMAN,tr|F6TC96|F6TC96_HUMAN,tr|A0A0G2JL47|A0A0G2JL47_HUMAN,tr|A0A024RCR6|A0A024RCR6_HUMAN,tr|A0A0G2JK23|A0A0G2JK23_HUMAN,tr|A0A1B0GX79|A0A1B0GX79_HUMAN" 20 1006.5084 1.46 43202 7930 2 1006.504677 504.2615 Large proline-rich protein BAG6 OS=Homo sapiens OX=9606 GN=BAG6 PE=1 SV=2 6 1913.7 - 3.87E+06 - - - -3.6592 - 1.598 0.419 - 197.6 1 2 0 -0.0037 9 0 0 0 1.08E+08 7.40E+07 - - - 3.4907 0.9996 221125_WJC_METTL3_EV_vs_WT_F04.07931.07931.2 0.0054 16-Sep K.ESEFDDEPK.F "sp|Q9Y2W1|TR150_HUMAN,tr|A0A3B3ITZ9|A0A3B3ITZ9_HUMAN" 2 1094.4404 3 43203 7931 2 1094.440724 548.2275 Thyroid hormone receptor-associated protein 3 OS=Homo sapiens OX=9606 GN=THRAP3 PE=1 SV=2 3.83 1913.7 - 3.05E+06 - - - 0.296 - 1.392 0.436 - 284.9 1 2 0 0.0003 9 0 0 0 1.29E+09 4.29E+08 - - - 3.218 0.9999 221125_WJC_METTL3_EV_vs_WT_F04.07934.07934.2 0.000252 18-Oct K.TLEEPVSTEK[136.11].N "sp|Q99590|SCAFB_HUMAN,tr|F8VXG7|F8VXG7_HUMAN" 2 1139.5801 0.97 43206 7934 2 1139.579435 570.7973 Protein SCAF11 OS=Homo sapiens OX=9606 GN=SCAF11 PE=1 SV=2 4.25 1914 - 649876 - - - -0.6134 - 2.351 0.474 - 239.4 1 2 0 -0.0007 10 0 0 0 3.20E+07 3.29E+07 - - - 4.9279 0.9997 221125_WJC_METTL3_EV_vs_WT_F04.07938.07938.2 0.0002 20-Aug K.LVMAGETTNSR[166.11].G "sp|P26358|DNMT1_HUMAN,tr|A0A7I2V5D0|A0A7I2V5D0_HUMAN,tr|A0A7I2V5F1|A0A7I2V5F1_HUMAN,tr|A0A7I2YQA8|A0A7I2YQA8_HUMAN,tr|A0A7I2YQQ0|A0A7I2YQQ0_HUMAN,tr|A0A7I2V311|A0A7I2V311_HUMAN,tr|A0A7I2V490|A0A7I2V490_HUMAN" 7 1187.5844 0.47 43208 7938 2 1187.583514 594.7995 DNA (cytosine-5)-methyltransferase 1 OS=Homo sapiens OX=9606 GN=DNMT1 PE=1 SV=2 6 1914.5 - 379877 - - - -0.7393 - 1.611 0.435 - 223.1 1 2 0 -0.0009 11 0 0 0 5.79E+06 1.24E+07 - - - 3.5436 0.9999 221125_WJC_METTL3_EV_vs_WT_F04.07941.07941.2 4.49E-07 18-Oct K.IINDNATYC[160.03]R.L "sp|O00567|NOP56_HUMAN,tr|A0A494C128|A0A494C128_HUMAN,tr|Q5JXT2|Q5JXT2_HUMAN" 3 1238.5714 0.89 43210 7941 2 1238.572161 620.293 Nucleolar protein 56 OS=Homo sapiens OX=9606 GN=NOP56 PE=1 SV=4 5.83 1914.9 - 545733 - - - 0.6378 - 1.996 0.558 - 263 1 2 0 0.0008 10 0 0 0 1.99E+07 2.23E+07 - - - 5.0913 0.999 221125_WJC_METTL3_EV_vs_WT_F04.07942.07942.2 1.34 12-Aug R.HLLVPER.E "sp|P35658|NU214_HUMAN,tr|A0A0A0MSW3|A0A0A0MSW3_HUMAN,tr|A0A494C1F2|A0A494C1F2_HUMAN" 3 862.5025 1.13 43211 7942 2 862.502782 432.2585 Nuclear pore complex protein Nup214 OS=Homo sapiens OX=9606 GN=NUP214 PE=1 SV=2 6.75 1914.9 - 1.63E+06 - - - 0.342 - 1.649 0.238 - 284.8 1 2 0 0.0003 7 0 0 0 7.65E+07 6.78E+07 - - - 2.3836 0.9998 221125_WJC_METTL3_EV_vs_WT_F04.07943.07943.2 5.10E-05 16-Aug K.ESEFDDEPK[136.11].F "sp|Q9Y2W1|TR150_HUMAN,tr|A0A3B3ITZ9|A0A3B3ITZ9_HUMAN" 2 1102.4546 3 43212 7943 2 1102.455486 552.2346 Thyroid hormone receptor-associated protein 3 OS=Homo sapiens OX=9606 GN=THRAP3 PE=1 SV=2 3.83 1915 - 1.57E+06 - - - 0.8037 - 1.535 0.554 - 240.8 1 2 0 0.0009 9 0 0 0 1.29E+09 4.29E+08 - - - 4.3723 0.9956 221125_WJC_METTL3_EV_vs_WT_F04.07944.07944.2 4.25E-05 18-Sep R.IYGETPEAC[160.03]R.Q sp|P51116|FXR2_HUMAN 1 1194.5339 1.69 43213 7944 2 1194.539298 598.2742 Fragile X mental retardation syndrome-related protein 2 OS=Homo sapiens OX=9606 GN=FXR2 PE=1 SV=2 4.53 1915.1 - 189485 - - - 4.4997 - 1.91 0.359 - 246.2 1 2 0 0.0054 10 0 0 0 3.98E+07 2.36E+07 - - - 3.4971 0.9783 221125_WJC_METTL3_EV_vs_WT_F04.07945.07945.2 0.216 24-May K.LPPGATAATATER.C sp|Q7L3S4|ZN771_HUMAN 1 1254.6568 1.11 43214 7945 2 1254.654716 628.3357 Zinc finger protein 771 OS=Homo sapiens OX=9606 GN=ZNF771 PE=1 SV=1 6 1915.3 - 150104 - - - -1.673 - 1.063 0.171 - 50 1 2 0 -0.0021 13 0 0 0 1.01E+07 9.11E+06 - - - 0.4601 0.9993 221125_WJC_METTL3_EV_vs_WT_F04.07948.07948.2 0.00491 16-Sep R.GIPAPEEER.T "sp|O95433|AHSA1_HUMAN,tr|H0YJU2|H0YJU2_HUMAN,tr|G3V438|G3V438_HUMAN" 3 996.4876 1.46 43215 7948 2 996.486724 499.2511 Activator of 90 kDa heat shock protein ATPase homolog 1 OS=Homo sapiens OX=9606 GN=AHSA1 PE=1 SV=1 4.25 1915.7 - 736592 - - - -0.9032 - 1.553 0.348 - 308.3 1 2 0 -0.0009 9 0 0 0 1.54E+08 1.05E+08 - - - 2.8845 0.998 221125_WJC_METTL3_EV_vs_WT_F04.07949.07949.2 0.0621 20-May R.EGVLTGSPEQK[136.11].E sp|Q92616|GCN1_HUMAN 1 1151.5914 1.41 43216 7949 2 1151.591456 576.803 eIF-2-alpha kinase activator GCN1 OS=Homo sapiens OX=9606 GN=GCN1 PE=1 SV=6 4.53 1915.8 - 96657.1 - - - 0.0764 - 1.328 0.267 - 55.4 1 2 0 0.0001 11 0 0 0 1.44E+07 1.02E+07 - - - 1.7804 0.9987 221125_WJC_METTL3_EV_vs_WT_F04.07950.07950.2 0.0771 18-Sep K.SVVAPPGAPK[136.11].K "sp|P15170|ERF3A_HUMAN,tr|H3BR35|H3BR35_HUMAN,tr|H3BSV8|H3BSV8_HUMAN" 3 929.5426 1.07 43217 7950 2 929.542762 465.7786 Eukaryotic peptide chain release factor GTP-binding subunit ERF3A OS=Homo sapiens OX=9606 GN=GSPT1 PE=1 SV=1 8.47 1915.9 - 868613 - - - 0.2098 - 1.593 0.244 - 271.7 1 2 0 0.0002 10 0 0 0 4.99E+07 4.68E+07 - - - 2.1428 0.9996 221125_WJC_METTL3_EV_vs_WT_F04.07956.07956.2 0.000502 16-Jul K.LQEYNVGGK[136.11].V "sp|P46379|BAG6_HUMAN,tr|F6UR09|F6UR09_HUMAN,tr|A0A7I2V508|A0A7I2V508_HUMAN,tr|F6U1F2|F6U1F2_HUMAN,tr|F6U341|F6U341_HUMAN,tr|F6WML8|F6WML8_HUMAN,tr|A0A0G2JJM1|A0A0G2JJM1_HUMAN,tr|X6REW1|X6REW1_HUMAN,tr|A0A7I2V3H1|A0A7I2V3H1_HUMAN,tr|A0A7P0MQS5|A0A7P0MQS5_HUMAN,tr|F6XTU0|F6XTU0_HUMAN,tr|F6X9W3|F6X9W3_HUMAN,tr|F6VEM6|F6VEM6_HUMAN,tr|A0A0G2JJR8|A0A0G2JJR8_HUMAN,tr|F6S6P2|F6S6P2_HUMAN,tr|F6TC96|F6TC96_HUMAN,tr|A0A0G2JL47|A0A0G2JL47_HUMAN,tr|A0A024RCR6|A0A024RCR6_HUMAN,tr|A0A0G2JK23|A0A0G2JK23_HUMAN,tr|A0A1B0GX79|A0A1B0GX79_HUMAN" 20 1014.5226 1.47 43222 7956 2 1014.521539 508.2686 Large proline-rich protein BAG6 OS=Homo sapiens OX=9606 GN=BAG6 PE=1 SV=2 6 1916.6 - 4.39E+06 - - - -1.0064 - 1.636 0.392 - 137.4 1 2 0 -0.001 9 0 0 0 1.10E+08 7.54E+07 - - - 3.3601 0.9999 221125_WJC_METTL3_EV_vs_WT_F04.07960.07960.2 1.82E-05 20-Nov R.YLSEVASGDNK.Q sp|P31946|1433B_HUMAN 1 1181.5564 1.17 43225 7960 2 1181.555736 591.7855 14-3-3 protein beta\alpha OS=Homo sapiens OX=9606 GN=YWHAB PE=1 SV=3 4.37 1917 - 1.21E+06 - - - -0.5891 - 2.095 0.58 - 341.7 1 2 0 -0.0007 11 0 0 0 7.04E+07 6.00E+07 - - - 5.3253 0.9997 221125_WJC_METTL3_EV_vs_WT_F04.07961.07961.2 0.00122 18-Oct R.IYGETPEAC[160.03]R[166.11].Q sp|P51116|FXR2_HUMAN 1 1204.5422 1.69 43226 7961 2 1204.541804 603.2784 Fragile X mental retardation syndrome-related protein 2 OS=Homo sapiens OX=9606 GN=FXR2 PE=1 SV=2 4.53 1917.2 - 409077 - - - -0.3229 - 1.578 0.429 - 281.4 1 2 0 -0.0004 10 0 0 0 3.98E+07 2.36E+07 - - - 3.4827 0.9999 221125_WJC_METTL3_EV_vs_WT_F04.07962.07962.2 4.81E-06 20-Dec K.IIEDQQESLNK[136.11].W sp|P05455|LA_HUMAN 1 1323.6762 1.06 43227 7962 2 1323.676606 662.8454 Lupus La protein OS=Homo sapiens OX=9606 GN=SSB PE=1 SV=2 4.14 1917.3 - 323493 - - - 0.3369 - 2.238 0.549 - 405.8 1 2 0 0.0004 11 0 0 0 1.16E+08 1.10E+08 - - - 5.2751 0.9993 221125_WJC_METTL3_EV_vs_WT_F04.07963.07963.2 0.0128 20-Sep K.IIEDQQESLNK.W sp|P05455|LA_HUMAN 1 1315.662 1.06 43228 7963 2 1315.663116 658.8383 Lupus La protein OS=Homo sapiens OX=9606 GN=SSB PE=1 SV=2 4.14 1917.4 - 309247 - - - 0.8786 - 1.531 0.366 - 198.4 1 2 0 0.0012 11 0 0 0 1.16E+08 1.10E+08 - - - 2.8961 0.9999 221125_WJC_METTL3_EV_vs_WT_F04.07970.07970.3 0.00107 Nov-36 K.TFQGKPIMAR.L "sp|Q71RC2|LARP4_HUMAN,tr|Q96J85|Q96J85_HUMAN,tr|X6RLN4|X6RLN4_HUMAN" 3 1147.6172 1.21 43234 7970 3 1147.617107 383.5463 La-related protein 4 OS=Homo sapiens OX=9606 GN=LARP4 PE=1 SV=3 11 1918.1 - 1.02E+06 - - - -0.0802 - 1.906 0.415 - 204.4 1 2 0 -0.0001 10 0 0 0 4.81E+07 3.97E+07 - - - 5.0505 0.9999 221125_WJC_METTL3_EV_vs_WT_F04.07972.07972.3 0.000755 Oct-36 K.TFQGK[136.11]PIMAR[166.11].L "sp|Q71RC2|LARP4_HUMAN,tr|Q96J85|Q96J85_HUMAN,tr|X6RLN4|X6RLN4_HUMAN" 3 1165.6397 1.21 43236 7972 3 1165.638855 389.5538 La-related protein 4 OS=Homo sapiens OX=9606 GN=LARP4 PE=1 SV=3 11 1918.3 - 801936 - - - -0.6983 - 2.067 0.395 - 144 1 2 0 -0.0008 10 0 0 0 4.79E+07 3.97E+07 - - - 5.0642 0.9994 221125_WJC_METTL3_EV_vs_WT_F04.07978.07978.2 0.109 14-Sep K.IDDVVNTR[166.11].- sp|P50991|TCPD_HUMAN 1 940.4853 0.34 43240 7978 2 940.48457 471.2499 T-complex protein 1 subunit delta OS=Homo sapiens OX=9606 GN=CCT4 PE=1 SV=4 4.21 1919.1 - 5.46E+06 - - - -0.8081 - 2.107 0.223 - 259 1 2 0 -0.0008 8 0 0 0 2.09E+08 6.22E+08 - - - 2.9355 0.9979 221125_WJC_METTL3_EV_vs_WT_F04.07980.07980.2 0.607 14-Jul R.QQIAEIEK[136.11].Q sp|Q6P2Q9|PRP8_HUMAN 1 965.5273 1.04 43242 7980 2 965.527446 483.7709 Pre-mRNA-processing-splicing factor 8 OS=Homo sapiens OX=9606 GN=PRPF8 PE=1 SV=2 4.53 1919.2 - 3.71E+06 - - - 0.1398 - 1.439 0.222 - 191.8 1 2 0 0.0001 8 0 0 0 1.09E+08 1.05E+08 - - - 1.7783 0.9996 221125_WJC_METTL3_EV_vs_WT_F04.07981.07981.2 0.179 16-Sep R.GEEVGELSR[166.11].G sp|P09543|CN37_HUMAN 1 984.4752 0.99 43243 7981 2 984.475571 493.2449 "2',3'-cyclic-nucleotide 3'-phosphodiesterase OS=Homo sapiens OX=9606 GN=CNP PE=1 SV=2" 4.25 1919.2 - 2.44E+06 - - - 0.4185 - 1.867 0.34 - 420.5 1 2 0 0.0004 9 0 0 0 1.03E+08 1.04E+08 - - - 3.3583 0.9989 221125_WJC_METTL3_EV_vs_WT_F04.07983.07983.2 0.00382 14-Oct K.IDDVVNTR.- sp|P50991|TCPD_HUMAN 1 930.4771 0.34 43245 7983 2 930.476577 466.2458 T-complex protein 1 subunit delta OS=Homo sapiens OX=9606 GN=CCT4 PE=1 SV=4 4.21 1919.4 - 1.37E+06 - - - -0.5191 - 1.781 0.212 - 335.6 1 2 0 -0.0005 8 0 0 0 2.09E+08 6.22E+08 - - - 2.3474 0.9993 221125_WJC_METTL3_EV_vs_WT_F04.07985.07985.2 0.0124 14-Sep K.TDEGIAYR.G sp|P32119|PRDX2_HUMAN 1 923.4349 0.96 43247 7985 2 923.433095 462.7247 Peroxiredoxin-2 OS=Homo sapiens OX=9606 GN=PRDX2 PE=1 SV=5 4.37 1919.6 - 781756 - - - -1.9124 - 1.9 0.324 - 418.5 1 2 0 -0.0018 8 0 0 0 2.27E+08 2.37E+08 - - - 3.3693 0.9997 221125_WJC_METTL3_EV_vs_WT_F04.07992.07992.2 4.71E-05 22-Dec R.LLDESESAASSR.A sp|Q8N108|MIER1_HUMAN 1 1263.5943 1.68 43252 7992 2 1263.592906 632.8044 Mesoderm induction early response protein 1 OS=Homo sapiens OX=9606 GN=MIER1 PE=1 SV=2 4.14 1920.4 - 390952 - - - -1.0826 - 1.859 0.408 - 352.3 1 2 0 -0.0014 12 0 0 0 5.93E+06 3.53E+06 - - - 3.6855 0.9963 221125_WJC_METTL3_EV_vs_WT_F04.07997.07997.2 0.267 12-Jul R.LNVC[160.03]VSK[136.11].Q "sp|Q8WVV9|HNRLL_HUMAN,sp|P14866|HNRPL_HUMAN,tr|M0QYT0|M0QYT0_HUMAN,tr|V9GYK2|V9GYK2_HUMAN,tr|C9IYN3|C9IYN3_HUMAN,tr|B7WPG3|B7WPG3_HUMAN,tr|A0A3B3ITJ4|A0A3B3ITJ4_HUMAN,tr|M0QXS5|M0QXS5_HUMAN,tr|H7C464|H7C464_HUMAN" 9 826.4462 1.22 43255 7997 2 826.44707 414.2304 Heterogeneous nuclear ribonucleoprotein L-like OS=Homo sapiens OX=9606 GN=HNRNPLL PE=1 SV=1 8.22 1921.1 - 2.72E+06 - - - 1.0237 - 1.629 0.129 - 157.2 1 2 0 0.0008 7 0 0 0 2.79E+08 2.30E+08 - - - 1.5397 0.936 221125_WJC_METTL3_EV_vs_WT_F04.07998.07998.2 8.57 12-Jun R.RYIGIVK.Q sp|P52597|HNRPF_HUMAN 1 847.528 0.76 43256 7998 2 847.527481 424.7713 Heterogeneous nuclear ribonucleoprotein F OS=Homo sapiens OX=9606 GN=HNRNPF PE=1 SV=3 9.99 1921.2 - 1.07E+06 - - - -0.5805 - 1.099 0.012 - 148 1 2 0 -0.0005 7 0 0 0 1.41E+08 1.85E+08 - - - -0.5714 0.9997 221125_WJC_METTL3_EV_vs_WT_F04.07999.07999.2 0.000228 14-Sep K.WESGYNTR.A "sp|P61626|LYSC_HUMAN,tr|A0A0B4J259|A0A0B4J259_HUMAN,tr|F8VV32|F8VV32_HUMAN" 3 1011.441 771.13 43257 7999 2 1011.441747 506.7278 Lysozyme C OS=Homo sapiens OX=9606 GN=LYZ PE=1 SV=1 6 1921.3 - 4.07E+06 - - - 0.7297 - 1.699 0.455 - 264.8 1 2 0 0.0007 8 0 0 0 3.19E+08 4.13E+05 - - - 4 0.9963 221125_WJC_METTL3_EV_vs_WT_F04.08001.08001.3 0.00765 13/36 R.TIQAHEGFVR.G "sp|Q9NV06|DCA13_HUMAN,tr|A0A087WT20|A0A087WT20_HUMAN,tr|B3KME9|B3KME9_HUMAN" 3 1156.5989 1.19 43259 8001 3 1156.598729 386.5402 DDB1- and CUL4-associated factor 13 OS=Homo sapiens OX=9606 GN=DCAF13 PE=1 SV=2 6.41 1921.5 - 470525 - - - -0.153 - 1.953 0.173 - 255.8 1 2 0 -0.0002 10 0 0 0 1.54E+07 1.29E+07 - - - 2.4236 0.9992 221125_WJC_METTL3_EV_vs_WT_F04.08006.08006.2 0.00281 14-Jul K.LQNDFAEK.E "sp|Q13948|CASP_HUMAN,sp|P39880|CUX1_HUMAN,tr|A0A2R8Y8D0|A0A2R8Y8D0_HUMAN,tr|A0A2R8Y852|A0A2R8Y852_HUMAN,tr|A0A2R8YDI1|A0A2R8YDI1_HUMAN" 5 963.4662 2.49 43262 8006 2 963.466005 482.7404 Protein CASP OS=Homo sapiens OX=9606 GN=CUX1 PE=1 SV=2 4.37 1922.2 - 4.90E+06 - - - -0.1619 - 1.628 0.277 - 119.2 1 2 0 -0.0002 8 0 0 0 1.98E+08 7.95E+07 - - - 2.5567 0.9994 221125_WJC_METTL3_EV_vs_WT_F04.08007.08007.2 0.0145 12-Aug R.LNVC[160.03]VSK.Q "sp|Q8WVV9|HNRLL_HUMAN,sp|P14866|HNRPL_HUMAN,tr|M0QYT0|M0QYT0_HUMAN,tr|V9GYK2|V9GYK2_HUMAN,tr|C9IYN3|C9IYN3_HUMAN,tr|B7WPG3|B7WPG3_HUMAN,tr|A0A3B3ITJ4|A0A3B3ITJ4_HUMAN,tr|M0QXS5|M0QXS5_HUMAN,tr|H7C464|H7C464_HUMAN" 9 818.432 1.21 43263 8007 2 818.431321 410.2233 Heterogeneous nuclear ribonucleoprotein L-like OS=Homo sapiens OX=9606 GN=HNRNPLL PE=1 SV=1 8.22 1922.2 - 4.06E+06 - - - -0.859 - 1.648 0.325 - 217.1 1 2 0 -0.0007 7 0 0 0 2.78E+08 2.29E+08 - - - 3.0241 0.994 221125_WJC_METTL3_EV_vs_WT_F04.08009.08009.2 0.0321 16-Aug R.TTILQSTGK.N "sp|Q6P1J9|CDC73_HUMAN,tr|A0A2R8YHB3|A0A2R8YHB3_HUMAN,tr|A0A1B0GUB2|A0A1B0GUB2_HUMAN,tr|A0A3B3IRP5|A0A3B3IRP5_HUMAN" 4 947.5288 1.17 43265 8009 2 947.525447 474.7717 Parafibromin OS=Homo sapiens OX=9606 GN=CDC73 PE=1 SV=1 8.41 1922.3 - 714275 - - - -3.4975 - 1.478 0.305 - 195.3 1 2 0 -0.0033 9 0 0 0 1.35E+08 1.16E+08 - - - 2.423 0.9375 221125_WJC_METTL3_EV_vs_WT_F04.08015.08015.2 0.0131 24-Aug G.GSYGSGGGGGGGR.G sp|P04264|K2C1_HUMAN 1 1024.4322 11.78 43269 8015 2 1024.432613 513.2234 "Keratin, type II cytoskeletal 1 OS=Homo sapiens OX=9606 GN=KRT1 PE=1 SV=6" 8.75 1923.1 - 1.64E+06 - - - 0.369 - 1.269 0.362 - 139.8 1 1 0 0.0004 13 0 0 0 8.89E+07 7.55E+06 - - - 2.326 0.9981 221125_WJC_METTL3_EV_vs_WT_F04.08021.08021.2 0.229 18-Aug K.AQAEVEGLGK.G "sp|Q15149|PLEC_HUMAN,tr|H0YDN1|H0YDN1_HUMAN" 2 1000.5189 2.63 43272 8021 2 1000.520636 501.2667 Plectin OS=Homo sapiens OX=9606 GN=PLEC PE=1 SV=3 4.53 1923.8 - 1.38E+06 - - - 1.7101 - 1.669 0.262 - 210.4 1 2 0 0.0017 10 0 0 0 3.26E+07 1.24E+07 - - - 2.4054 1 221125_WJC_METTL3_EV_vs_WT_F04.08026.08026.3 2.06E-05 13/36 R.VDAVHADVYR[166.11].V "sp|Q15003|CND2_HUMAN,tr|C9J470|C9J470_HUMAN,tr|E9PHA2|E9PHA2_HUMAN" 3 1153.5755 0.94 43275 8026 3 1153.574393 385.5325 Condensin complex subunit 2 OS=Homo sapiens OX=9606 GN=NCAPH PE=1 SV=3 5.21 1924.4 - 825151 - - - -0.996 - 2.26 0.496 - 315.5 1 2 0 -0.0011 10 0 0 0 5.31E+07 5.66E+07 - - - 6.4508 0.9995 221125_WJC_METTL3_EV_vs_WT_F04.08032.08032.2 0.00584 16-Oct R.TTILQSTGK[136.11].N "sp|Q6P1J9|CDC73_HUMAN,tr|A0A2R8YHB3|A0A2R8YHB3_HUMAN,tr|A0A1B0GUB2|A0A1B0GUB2_HUMAN,tr|A0A3B3IRP5|A0A3B3IRP5_HUMAN" 4 955.543 1.17 43278 8032 2 955.542392 478.7788 Parafibromin OS=Homo sapiens OX=9606 GN=CDC73 PE=1 SV=1 8.41 1925.2 - 2.55E+06 - - - -0.5955 - 1.679 0.351 - 339 1 2 0 -0.0006 9 0 0 0 1.36E+08 1.16E+08 - - - 3.1325 1 221125_WJC_METTL3_EV_vs_WT_F04.08033.08033.3 8.97E-06 Nov-36 R.VDAVHADVYR.V "sp|Q15003|CND2_HUMAN,tr|C9J470|C9J470_HUMAN,tr|E9PHA2|E9PHA2_HUMAN" 3 1143.5673 0.9 43279 8033 3 1143.566826 382.1964 Condensin complex subunit 2 OS=Homo sapiens OX=9606 GN=NCAPH PE=1 SV=3 5.21 1925.3 - 1.37E+06 - - - -0.39 - 2.307 0.491 - 240.3 1 2 0 -0.0004 10 0 0 0 5.10E+07 5.65E+07 - - - 6.4554 0.9999 221125_WJC_METTL3_EV_vs_WT_F04.08037.08037.2 1.42E-05 20-Dec R.QLEEAEEEATR.A sp|P35580|MYH10_HUMAN 1 1303.5892 1.08 43281 8037 2 1303.588647 652.8019 Myosin-10 OS=Homo sapiens OX=9606 GN=MYH10 PE=1 SV=3 3.98 1925.8 - 226914 - - - -0.4158 - 2.357 0.579 - 805.8 1 2 0 -0.0005 11 0 0 0 1.25E+07 1.16E+07 - - - 5.6368 0.9998 221125_WJC_METTL3_EV_vs_WT_F04.08039.08039.2 9.59E-05 20-Nov R.LSSGEDTTELR.K "sp|Q9P2N5|RBM27_HUMAN,tr|U3KPZ7|U3KPZ7_HUMAN" 2 1206.5728 1.26 43283 8039 2 1206.572664 604.2937 RNA-binding protein 27 OS=Homo sapiens OX=9606 GN=RBM27 PE=1 SV=2 4.14 1926 - 1.03E+06 - - - -0.1218 - 2.094 0.423 - 377.5 1 2 0 -0.0001 11 0 0 0 2.81E+07 2.22E+07 - - - 4.1646 0.9992 221125_WJC_METTL3_EV_vs_WT_F04.08040.08040.2 0.00139 18-Jul R.VDAVHADVYR[166.11].V "sp|Q15003|CND2_HUMAN,tr|C9J470|C9J470_HUMAN,tr|E9PHA2|E9PHA2_HUMAN" 3 1153.5755 5.46 43284 8040 2 1153.576432 577.795 Condensin complex subunit 2 OS=Homo sapiens OX=9606 GN=NCAPH PE=1 SV=3 5.21 1926.2 - 145976 - - - 0.7715 - 1.455 0.366 - 152 1 2 0 0.0009 10 0 0 0 2.58E+07 4.72E+06 - - - 2.7908 0.9747 221125_WJC_METTL3_EV_vs_WT_F04.08043.08043.2 8.16 12-Jun K.IIAPPER.K "sp|P63261|ACTG_HUMAN,sp|P68133|ACTS_HUMAN,sp|P62736|ACTA_HUMAN,sp|P68032|ACTC_HUMAN,sp|Q562R1|ACTBL_HUMAN,sp|P60709|ACTB_HUMAN,sp|P63267|ACTH_HUMAN,tr|A0A2R8YFE2|A0A2R8YFE2_HUMAN,tr|A0A804GS07|A0A804GS07_HUMAN,tr|A0A6Q8PFE4|A0A6Q8PFE4_HUMAN,tr|A0A804HKV3|A0A804HKV3_HUMAN,tr|I3L4N8|I3L4N8_HUMAN" 12 794.465 0.75 43285 8043 2 794.464973 398.2398 "Actin, cytoplasmic 2 OS=Homo sapiens OX=9606 GN=ACTG1 PE=1 SV=1" 6 1926.6 - 523103 - - - -0.0818 - 1.205 0.05 - 135.7 1 2 0 -0.0001 7 0 0 0 1.34E+07 1.79E+07 - - - 0.0012 0.9985 221125_WJC_METTL3_EV_vs_WT_F04.08057.08057.2 0.00244 16-Jul R.SLPVEEQPK[136.11].Q sp|Q6P2Q9|PRP8_HUMAN 1 1033.5535 1.39 43292 8057 2 1033.554956 517.784 Pre-mRNA-processing-splicing factor 8 OS=Homo sapiens OX=9606 GN=PRPF8 PE=1 SV=2 4.53 1928.4 - 793554 - - - 1.3836 - 1.374 0.338 - 190.9 1 2 0 0.0014 9 0 0 0 1.34E+08 9.58E+07 - - - 2.4562 0.9969 221125_WJC_METTL3_EV_vs_WT_F04.08064.08064.2 0.308 13/20 R.LASAGVDTNVR[166.11].L sp|Q13112|CAF1B_HUMAN 1 1111.5861 1.46 43296 8064 2 1111.587156 556.8003 Chromatin assembly factor 1 subunit B OS=Homo sapiens OX=9606 GN=CHAF1B PE=1 SV=1 5.84 1929.2 - 471358 - - - 0.9446 - 1.904 0.118 - 677.1 1 2 0 0.001 11 0 0 0 7.76E+07 5.32E+07 - - - 1.6543 0.9695 221125_WJC_METTL3_EV_vs_WT_F04.08066.08066.2 0.625 18-Jun K.IAVAAQNC[160.03]YK[136.11].V sp|P60174|TPIS_HUMAN 1 1144.579 1.62 43298 8066 2 1144.582259 573.2968 Triosephosphate isomerase OS=Homo sapiens OX=9606 GN=TPI1 PE=1 SV=4 8.2 1929.5 - 444649 - - - 2.822 - 1.503 0.102 - 95.8 2 2 0 0.0032 10 0 0 0 3.61E+07 2.23E+07 - - - 0.7962 0.999 221125_WJC_METTL3_EV_vs_WT_F04.08069.08069.2 0.00967 16-Jul K.AAIAQLNGK.E sp|Q96PK6|RBM14_HUMAN 1 884.508 1.91 43299 8069 2 884.508974 443.2613 RNA-binding protein 14 OS=Homo sapiens OX=9606 GN=RBM14 PE=1 SV=2 8.8 1929.9 - 3.52E+06 - - - 1.1396 - 1.565 0.319 - 120.2 1 2 0 0.001 9 0 0 0 4.67E+09 2.45E+09 - - - 2.6926 0.9993 221125_WJC_METTL3_EV_vs_WT_F04.08070.08070.2 0.00315 16-Aug R.SLPVEEQPK.Q sp|Q6P2Q9|PRP8_HUMAN 1 1025.5393 1.39 43300 8070 2 1025.540632 513.7769 Pre-mRNA-processing-splicing factor 8 OS=Homo sapiens OX=9606 GN=PRPF8 PE=1 SV=2 4.53 1929.9 - 2.13E+06 - - - 1.2735 - 1.425 0.413 - 249.6 1 2 0 0.0013 9 0 0 0 1.34E+08 9.58E+07 - - - 3.1156 0.9999 221125_WJC_METTL3_EV_vs_WT_F04.08072.08072.2 0.000158 13/20 R.QLEEAEEEATR[166.11].A sp|P35580|MYH10_HUMAN 1 1313.5975 1.08 43302 8072 2 1313.59892 657.806 Myosin-10 OS=Homo sapiens OX=9606 GN=MYH10 PE=1 SV=3 3.98 1930.2 - 349123 - - - 1.1122 - 2.422 0.501 - 897.8 1 2 0 0.0015 11 0 0 0 1.25E+07 1.16E+07 - - - 5.134 0.9982 221125_WJC_METTL3_EV_vs_WT_F04.08077.08077.2 0.172 14-Aug K.VTQNLPMK.E "sp|Q1KMD3|HNRL2_HUMAN,tr|H3BQZ7|H3BQZ7_HUMAN" 2 929.5004 2.56 43305 8077 2 929.501784 465.7575 Heterogeneous nuclear ribonucleoprotein U-like protein 2 OS=Homo sapiens OX=9606 GN=HNRNPUL2 PE=1 SV=1 8.72 1930.9 - 2.20E+06 - - - 1.4481 - 1.52 0.271 - 250 1 2 0 0.0013 8 0 0 0 5.26E+07 2.05E+07 - - - 2.305 0.9996 221125_WJC_METTL3_EV_vs_WT_F04.08079.08079.2 0.00844 16-Sep K.AAIAQLNGK[136.11].E sp|Q96PK6|RBM14_HUMAN 1 892.5222 1.91 43307 8079 2 892.523421 447.2684 RNA-binding protein 14 OS=Homo sapiens OX=9606 GN=RBM14 PE=1 SV=2 8.8 1931 - 5.89E+06 - - - 1.4061 - 1.978 0.377 - 224.6 1 2 0 0.0013 9 0 0 0 4.67E+09 2.45E+09 - - - 3.7984 0.9998 221125_WJC_METTL3_EV_vs_WT_F04.08080.08080.3 0.00887 Oct-44 R.LGSAHPEAPALR.A "sp|Q9Y5J3|HEY1_HUMAN,tr|A0A6I8PRS3|A0A6I8PRS3_HUMAN,tr|A0A6I8PRC2|A0A6I8PRC2_HUMAN,tr|B4DEI9|B4DEI9_HUMAN" 4 1217.6517 0.37 43308 8080 3 1217.652559 406.8912 Hairy\enhancer-of-split related with YRPW motif protein 1 OS=Homo sapiens OX=9606 GN=HEY1 PE=1 SV=1 6.75 1931.2 - 601421 - - - 0.7301 - 2.123 0.34 - 92.5 1 2 0 0.0009 12 0 0 0 1.10E+08 2.98E+08 - - - 4.4172 0.9972 221125_WJC_METTL3_EV_vs_WT_F04.08084.08084.2 9.68E-05 18-Sep R.AALESGISTK.Q "sp|Q14168|MPP2_HUMAN,tr|B4DZ84|B4DZ84_HUMAN,tr|D3DX49|D3DX49_HUMAN,tr|A0A0A0MRU0|A0A0A0MRU0_HUMAN,tr|A0A0C4DH75|A0A0C4DH75_HUMAN,tr|A0A0D9SFF8|A0A0D9SFF8_HUMAN,tr|D3DX48|D3DX48_HUMAN" 7 975.5237 1.15 43311 8084 2 975.527847 488.7691 MAGUK p55 subfamily member 2 OS=Homo sapiens OX=9606 GN=MPP2 PE=1 SV=3 6.05 1931.7 - 773077 - - - 4.2757 - 1.786 0.433 - 181.2 1 2 0 0.0042 10 0 0 0 1.47E+07 1.28E+07 - - - 3.8567 0.9886 221125_WJC_METTL3_EV_vs_WT_F04.08086.08086.2 0.0529 14-Aug R.QVNITVQK[136.11].K "sp|Q9P035|HACD3_HUMAN,tr|H3BPZ1|H3BPZ1_HUMAN,tr|H3BS72|H3BS72_HUMAN" 3 936.5484 1.09 43312 8086 2 936.548726 469.2815 Very-long-chain (3R)-3-hydroxyacyl-CoA dehydratase 3 OS=Homo sapiens OX=9606 GN=HACD3 PE=1 SV=2 8.75 1931.9 - 1.83E+06 - - - 0.3684 - 1.404 0.068 - 277.3 1 2 0 0.0003 8 0 0 0 8.45E+07 7.76E+07 - - - 0.5665 0.9918 221125_WJC_METTL3_EV_vs_WT_F04.08087.08087.2 0.0192 14-Jun R.DGPGNPLR.H "sp|Q93009|UBP7_HUMAN,tr|A0A669KBL1|A0A669KBL1_HUMAN,tr|H3BND8|H3BND8_HUMAN" 3 824.4141 1.4 43313 8087 2 824.415207 413.2143 Ubiquitin carboxyl-terminal hydrolase 7 OS=Homo sapiens OX=9606 GN=USP7 PE=1 SV=2 5.84 1931.9 - 1.50E+06 - - - 1.384 - 1.317 0.164 - 101 1 2 0 0.0011 8 0 0 0 8.44E+07 6.02E+07 - - - 1.0824 0.9986 221125_WJC_METTL3_EV_vs_WT_F04.08092.08092.2 0.239 12-Jul R.FSGVPDR.F "sp|A0A075B6R9|KVD24_HUMAN,sp|A0A0C4DH68|KV224_HUMAN,sp|A2NJV5|KV229_HUMAN,sp|A0A075B6S2|KVD29_HUMAN,sp|A0A0A0MRZ7|KVD26_HUMAN" 5 776.3817 10.47 43316 8092 2 776.382245 389.1981 Probable non-functional immunoglobulin kappa variable 2D-24 OS=Homo sapiens OX=9606 GN=IGKV2D-24 PE=1 SV=1 5.84 1932.6 - 1.10E+06 - - - 0.6981 - 1.53 0.25 - 155.9 1 2 0 0.0005 7 0 0 0 9.35E+06 8.93E+05 - - - 2.2348 0.9892 221125_WJC_METTL3_EV_vs_WT_F04.08095.08095.2 0.123 12-Jul R.KLPDLEK.T sp|Q9NX62|IMPA3_HUMAN 1 841.4909 0.68 43319 8095 2 841.490694 421.7527 "Golgi-resident adenosine 3',5'-bisphosphate 3'-phosphatase OS=Homo sapiens OX=9606 GN=BPNT2 PE=1 SV=1" 6.07 1932.9 - 577545 - - - -0.2674 - 1.309 0.091 - 229.5 1 2 0 -0.0002 7 0 0 0 2.88E+07 4.23E+07 - - - 0.5662 0.9976 221125_WJC_METTL3_EV_vs_WT_F04.08100.08100.2 0.0584 14-Sep R.QVNITVQK.K "sp|Q9P035|HACD3_HUMAN,tr|H3BPZ1|H3BPZ1_HUMAN,tr|H3BS72|H3BS72_HUMAN" 3 928.5342 0.99 43322 8100 2 928.534466 465.2744 Very-long-chain (3R)-3-hydroxyacyl-CoA dehydratase 3 OS=Homo sapiens OX=9606 GN=HACD3 PE=1 SV=2 8.75 1933.5 - 2.46E+06 - - - 0.3069 - 1.586 0.169 - 383.8 1 2 0 0.0003 8 0 0 0 7.64E+07 7.71E+07 - - - 1.6801 0.9995 221125_WJC_METTL3_EV_vs_WT_F04.08102.08102.2 0.0679 18-Jul K.DAEIPEGAAR[166.11].G "sp|O14654|IRS4_HUMAN,tr|A0A804CF45|A0A804CF45_HUMAN" 2 1037.5017 0.84 43324 8102 2 1037.501434 519.7581 Insulin receptor substrate 4 OS=Homo sapiens OX=9606 GN=IRS4 PE=1 SV=1 4.14 1933.7 - 1.50E+06 - - - -0.2641 - 1.729 0.332 - 180 1 2 0 -0.0003 10 0 0 0 2.20E+08 2.62E+08 - - - 3.0214 0.9999 221125_WJC_METTL3_EV_vs_WT_F04.08107.08107.2 0.000879 16-Oct R.QVSDDLTER[166.11].A "sp|P35232|PHB_HUMAN,tr|C9JZ20|C9JZ20_HUMAN,tr|E7ESE2|E7ESE2_HUMAN,tr|E9PCW0|E9PCW0_HUMAN,tr|C9JW96|C9JW96_HUMAN" 5 1071.5072 1.54 43327 8107 2 1071.507246 536.7609 Prohibitin OS=Homo sapiens OX=9606 GN=PHB PE=1 SV=1 4.03 1934.3 - 5.96E+06 - - - 0.0551 - 1.993 0.473 - 431.4 1 2 0 0.0001 9 0 0 0 2.13E+08 1.38E+08 - - - 4.5297 0.7826 221125_WJC_METTL3_EV_vs_WT_F04.08108.08108.2 6.98 14-Jun R.QPSVTIGR[166.11].N sp|P85037|FOXK1_HUMAN 1 866.4849 1.38 43328 8108 2 866.487548 434.2497 Forkhead box protein K1 OS=Homo sapiens OX=9606 GN=FOXK1 PE=1 SV=1 9.75 1934.4 - 456711 - - - 3.0145 - 1.114 0.016 - 97.9 1 2 0 0.0026 8 0 0 0 4.87E+07 3.53E+07 - - - -0.5161 0.9994 221125_WJC_METTL3_EV_vs_WT_F04.08109.08109.2 0.0416 18-Aug K.LTVSSVNNPR.K sp|Q86TB9|PATL1_HUMAN 1 1085.5829 1.28 43329 8109 2 1085.584551 543.7987 Protein PAT1 homolog 1 OS=Homo sapiens OX=9606 GN=PATL1 PE=1 SV=2 9.75 1934.5 - 882247 - - - 1.5006 - 1.724 0.374 - 182.1 1 2 0 0.0016 10 0 0 0 3.87E+07 3.02E+07 - - - 3.3231 0.9994 221125_WJC_METTL3_EV_vs_WT_F04.08110.08110.2 0.00083 18-Sep K.SAVTTVVNPK.Y "sp|P05556|ITB1_HUMAN,tr|A0A7I2V2F9|A0A7I2V2F9_HUMAN,tr|H7C4K3|H7C4K3_HUMAN,tr|E7EUI6|E7EUI6_HUMAN" 4 1014.571 1.81 43330 8110 2 1014.569323 508.2928 Integrin beta-1 OS=Homo sapiens OX=9606 GN=ITGB1 PE=1 SV=2 8.47 1934.6 - 670487 - - - -1.6135 - 1.778 0.381 - 223.2 1 2 0 -0.0016 10 0 0 0 5.41E+07 3.00E+07 - - - 3.4609 0.9995 221125_WJC_METTL3_EV_vs_WT_F04.08112.08112.2 2.46E-06 20-Jul R.VVTTC[160.03]ADC[160.03]NLR.L "sp|Q9H967|WDR76_HUMAN,tr|A0A0C4DFX7|A0A0C4DFX7_HUMAN" 2 1307.5962 0.49 43332 8112 2 1307.599443 654.8054 WD repeat-containing protein 76 OS=Homo sapiens OX=9606 GN=WDR76 PE=1 SV=2 5.79 1934.9 - 165049 - - - 2.4755 - 1.441 0.611 - 174.9 1 2 0 0.0032 11 0 0 0 3.16E+06 6.49E+06 - - - 4.5412 0.9999 221125_WJC_METTL3_EV_vs_WT_F04.08116.08116.2 1.96E-05 16-Sep R.QVSDDLTER.A "sp|P35232|PHB_HUMAN,tr|C9JZ20|C9JZ20_HUMAN,tr|E7ESE2|E7ESE2_HUMAN,tr|E9PCW0|E9PCW0_HUMAN,tr|C9JW96|C9JW96_HUMAN" 5 1061.4989 1.68 43335 8116 2 1061.499251 531.7567 Prohibitin OS=Homo sapiens OX=9606 GN=PHB PE=1 SV=1 4.03 1935.4 - 8.80E+06 - - - 0.3146 - 1.871 0.506 - 366.3 1 2 0 0.0003 9 0 0 0 2.28E+08 1.36E+08 - - - 4.5906 0.9996 221125_WJC_METTL3_EV_vs_WT_F04.08118.08118.2 0.00378 14-Jul K.YTC[160.03]SFC[160.03]GK[136.11].T "sp|P61513|RL37A_HUMAN,sp|A6NKH3|RL37L_HUMAN,tr|E9PEL3|E9PEL3_HUMAN,tr|G5E9R3|G5E9R3_HUMAN,tr|C9J4Z3|C9J4Z3_HUMAN,tr|M0R2L6|M0R2L6_HUMAN,tr|M0R0A1|M0R0A1_HUMAN,tr|Q6P4E4|Q6P4E4_HUMAN" 8 1029.4139 0.91 43336 8118 2 1029.413549 515.7142 60S ribosomal protein L37a OS=Homo sapiens OX=9606 GN=RPL37A PE=1 SV=2 8.05 1935.6 - 8.31E+06 - - - -0.3779 - 1.462 0.427 - 144.2 1 2 0 -0.0004 8 0 0 0 2.13E+08 2.33E+08 - - - 3.3402 0.9999 221125_WJC_METTL3_EV_vs_WT_F04.08120.08120.2 0.0473 14-Jul K.YTC[160.03]SFC[160.03]GK.T "sp|P61513|RL37A_HUMAN,sp|A6NKH3|RL37L_HUMAN,tr|E9PEL3|E9PEL3_HUMAN,tr|G5E9R3|G5E9R3_HUMAN,tr|C9J4Z3|C9J4Z3_HUMAN,tr|M0R2L6|M0R2L6_HUMAN,tr|M0R0A1|M0R0A1_HUMAN,tr|Q6P4E4|Q6P4E4_HUMAN" 8 1021.3997 0.91 43338 8120 2 1021.399624 511.7071 60S ribosomal protein L37a OS=Homo sapiens OX=9606 GN=RPL37A PE=1 SV=2 8.05 1935.7 - 6.49E+06 - - - -0.1116 - 1.498 0.713 - 166.1 1 2 0 -0.0001 8 0 0 0 2.12E+08 2.33E+08 - - - 5.526 0.8503 221125_WJC_METTL3_EV_vs_WT_F04.08122.08122.2 3.26 12-Jun R.NQELLTR.L "sp|Q9Y6D9|MD1L1_HUMAN,tr|C9JJ38|C9JJ38_HUMAN,tr|C9JIR0|C9JIR0_HUMAN" 3 872.4716 1.95 43340 8122 2 872.470025 437.2431 Mitotic spindle assembly checkpoint protein MAD1 OS=Homo sapiens OX=9606 GN=MAD1L1 PE=1 SV=2 6 1935.9 - 426212 - - - -1.7823 - 1.115 0.004 - 123.8 3 2 0 -0.0016 7 0 0 0 2.62E+07 1.34E+07 - - - -0.7982 0.9995 221125_WJC_METTL3_EV_vs_WT_F04.08125.08125.2 0.0126 14-Jul R.QVVELQNR.L sp|Q86VS8|HOOK3_HUMAN 1 984.5352 1.79 43342 8125 2 984.534718 493.2749 Protein Hook homolog 3 OS=Homo sapiens OX=9606 GN=HOOK3 PE=1 SV=2 6 1936.2 - 1.50E+06 - - - -0.5332 - 1.406 0.404 - 243.4 1 2 0 -0.0005 8 0 0 0 4.74E+07 2.65E+07 - - - 3.0525 0.9998 221125_WJC_METTL3_EV_vs_WT_F04.08126.08126.2 8.12E-06 13/24 K.GPGEVAGTVTGQK[136.11].R "sp|Q86U44|MTA70_HUMAN,tr|F5H6D8|F5H6D8_HUMAN,tr|H0YFV6|H0YFV6_HUMAN,tr|B4DTN4|B4DTN4_HUMAN" 4 1207.6288 0.01 43343 8126 2 1207.626512 604.8217 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 6 1936.4 - 386512 - - - -1.9079 - 2.457 0.558 - 674.2 1 2 0 -0.0023 13 0 0 0 3.08E+05 5.72E+07 - - - 5.4688 0.9998 221125_WJC_METTL3_EV_vs_WT_F04.08129.08129.2 0.00152 16-Oct K.SAAMTLNER.F "sp|Q9NYF8|BCLF1_HUMAN,tr|E9PKI6|E9PKI6_HUMAN,tr|A0A1W2PQ43|A0A1W2PQ43_HUMAN,tr|E9PK91|E9PK91_HUMAN,tr|E9PK09|E9PK09_HUMAN,tr|E9PQN2|E9PQN2_HUMAN" 6 991.4757 1.81 43344 8129 2 991.474076 496.7451 Bcl-2-associated transcription factor 1 OS=Homo sapiens OX=9606 GN=BCLAF1 PE=1 SV=2 5.72 1936.8 - 926294 - - - -1.6178 - 2.087 0.466 - 534 1 2 0 -0.0016 9 0 0 0 1.06E+10 5.86E+09 - - - 4.6109 0.998 221125_WJC_METTL3_EV_vs_WT_F04.08133.08133.2 0.00181 22-Aug R.AGGEELDEGVAK.D sp|Q32MZ4|LRRF1_HUMAN 1 1173.5513 0.6 43347 8133 2 1173.547443 587.7829 Leucine-rich repeat flightless-interacting protein 1 OS=Homo sapiens OX=9606 GN=LRRFIP1 PE=1 SV=2 4 1937.2 - 460219 - - - -3.3267 - 1.578 0.424 - 189.2 1 2 0 -0.0039 12 0 0 0 1.05E+07 1.75E+07 - - - 3.3717 0.9922 221125_WJC_METTL3_EV_vs_WT_F04.08138.08138.3 0.0425 Oct-44 R.LGSAHPEAPALR[166.11].A "sp|Q9Y5J3|HEY1_HUMAN,tr|A0A6I8PRS3|A0A6I8PRS3_HUMAN,tr|A0A6I8PRC2|A0A6I8PRC2_HUMAN,tr|B4DEI9|B4DEI9_HUMAN" 4 1227.6599 1.99 43350 8138 3 1227.6559 410.2273 Hairy\enhancer-of-split related with YRPW motif protein 1 OS=Homo sapiens OX=9606 GN=HEY1 PE=1 SV=1 6.75 1937.8 - 1.53E+06 - - - -3.2908 - 1.717 0.261 - 97 1 2 0 -0.004 12 0 0 0 9.49E+07 4.76E+07 - - - 2.9472 0.9996 221125_WJC_METTL3_EV_vs_WT_F04.08140.08140.2 0.261 16-Aug R.GAAGDWGER.A "sp|Q14978|NOLC1_HUMAN,tr|A0A0A0MRM9|A0A0A0MRM9_HUMAN" 2 917.3991 2.11 43351 8140 2 917.397819 459.7068 Nucleolar and coiled-body phosphoprotein 1 OS=Homo sapiens OX=9606 GN=NOLC1 PE=1 SV=2 4.37 1938 - 1.91E+06 - - - -1.4443 - 1.867 0.382 - 316.1 1 2 0 -0.0013 9 0 0 0 2.71E+08 1.28E+08 - - - 3.6683 0.9931 221125_WJC_METTL3_EV_vs_WT_F04.08141.08141.2 0.024 14-Jun R.GEGMPQYR[166.11].N sp|O60884|DNJA2_HUMAN 1 946.4206 0.82 43352 8141 2 946.417435 474.2176 DnaJ homolog subfamily A member 2 OS=Homo sapiens OX=9606 GN=DNAJA2 PE=1 SV=1 6 1938.1 - 1.02E+06 - - - -3.3664 - 1.239 0.344 - 51.8 1 2 0 -0.0032 8 0 0 0 8.59E+07 1.04E+08 - - - 2.2271 0.8039 221125_WJC_METTL3_EV_vs_WT_F04.08142.08142.2 2.61 14-Jun R.QPSVTIGR.N sp|P85037|FOXK1_HUMAN 1 856.4767 1.23 43353 8142 2 856.475372 429.2456 Forkhead box protein K1 OS=Homo sapiens OX=9606 GN=FOXK1 PE=1 SV=1 9.75 1938.2 - 945086 - - - -1.5108 - 1.002 0.034 - 108.7 8 2 0 -0.0013 8 0 0 0 4.29E+07 3.48E+07 - - - -1.1057 0.9951 221125_WJC_METTL3_EV_vs_WT_F04.08148.08148.2 0.00123 16-Aug K.NMMAAC[160.03]DPR.H "sp|P04350|TBB4A_HUMAN,sp|Q9BVA1|TBB2B_HUMAN,sp|A6NNZ2|TBB8B_HUMAN,sp|P07437|TBB5_HUMAN,sp|Q13509|TBB3_HUMAN,sp|Q13885|TBB2A_HUMAN,sp|P68371|TBB4B_HUMAN,sp|Q9BUF5|TBB6_HUMAN,sp|Q3ZCM7|TBB8_HUMAN,tr|A0A0B4J269|A0A0B4J269_HUMAN,tr|Q5ST81|Q5ST81_HUMAN,tr|Q5JP53|Q5JP53_HUMAN,tr|K7ESM5|K7ESM5_HUMAN,tr|A0A075B736|A0A075B736_HUMAN,tr|Q5SQY0|Q5SQY0_HUMAN" 15 1064.4202 0.5 43355 8148 2 1064.413927 533.2174 Tubulin beta-4A chain OS=Homo sapiens OX=9606 GN=TUBB4A PE=1 SV=2 5.83 1939 - 2.48E+06 - - - -5.852 - 1.535 0.585 - 216.2 1 2 0 -0.0062 9 0 0 0 1.02E+08 2.06E+08 - - - 4.5996 0.9997 221125_WJC_METTL3_EV_vs_WT_F04.08150.08150.2 0.029 16-Sep R.GAAGDWGER[166.11].A "sp|Q14978|NOLC1_HUMAN,tr|A0A0A0MRM9|A0A0A0MRM9_HUMAN" 2 927.4074 2.11 43357 8150 2 927.406037 464.711 Nucleolar and coiled-body phosphoprotein 1 OS=Homo sapiens OX=9606 GN=NOLC1 PE=1 SV=2 4.37 1939.2 - 1.90E+06 - - - -1.4848 - 1.853 0.449 - 384.7 1 2 0 -0.0014 9 0 0 0 2.71E+08 1.28E+08 - - - 4.1413 0.9992 221125_WJC_METTL3_EV_vs_WT_F04.08156.08156.2 0.000199 18-Aug K.STC[160.03]IYGGAPK[136.11].G "sp|Q92841|DDX17_HUMAN,sp|P17844|DDX5_HUMAN,tr|A0A7I2V5F5|A0A7I2V5F5_HUMAN,tr|J3KRZ1|J3KRZ1_HUMAN,tr|A0A7I2V507|A0A7I2V507_HUMAN,tr|A0A5H1ZRQ2|A0A5H1ZRQ2_HUMAN,tr|J3KTA4|J3KTA4_HUMAN,tr|A0A0G2JLI4|A0A0G2JLI4_HUMAN,tr|A0A1X7SBZ2|A0A1X7SBZ2_HUMAN,tr|A0A7I2V2S0|A0A7I2V2S0_HUMAN,tr|J3QRQ7|J3QRQ7_HUMAN" 11 1060.5103 1.57 43358 8156 2 1060.50712 531.2624 Probable ATP-dependent RNA helicase DDX17 OS=Homo sapiens OX=9606 GN=DDX17 PE=1 SV=2 7.92 1940.1 - 3.61E+06 - - - -2.9806 - 1.541 0.532 - 240.6 1 2 0 -0.0032 10 0 0 0 7.10E+08 4.51E+08 - - - 4.1764 0.9994 221125_WJC_METTL3_EV_vs_WT_F04.08157.08157.2 0.0119 14-Jul K.VC[160.03]FDC[160.03]GAK[136.11].N "sp|Q9NP61|ARFG3_HUMAN,tr|B0QYV9|B0QYV9_HUMAN,tr|B0QYV8|B0QYV8_HUMAN" 3 963.4034 1.17 43359 8157 2 963.401513 482.709 ADP-ribosylation factor GTPase-activating protein 3 OS=Homo sapiens OX=9606 GN=ARFGAP3 PE=1 SV=1 5.79 1940.1 - 1.78E+06 - - - -1.9307 - 1.398 0.481 - 128.6 1 2 0 -0.0019 8 0 0 0 8.68E+07 7.43E+07 - - - 3.6036 0.962 221125_WJC_METTL3_EV_vs_WT_F04.08159.08159.2 1.52 14-May R.GEGMPQYR.N sp|O60884|DNJA2_HUMAN 1 936.4124 0.82 43361 8159 2 936.41461 469.2135 DnaJ homolog subfamily A member 2 OS=Homo sapiens OX=9606 GN=DNAJA2 PE=1 SV=1 6 1940.2 - 1.03E+06 - - - 2.4124 - 1.09 0.185 - 94 3 2 0 0.0023 8 0 0 0 5.12E+07 6.28E+07 - - - 0.4535 0.9971 221125_WJC_METTL3_EV_vs_WT_F04.08164.08164.2 0.235 14-Sep K.R[166.11]VIDYAVK[136.11].L "sp|P38117|ETFB_HUMAN,tr|M0QY67|M0QY67_HUMAN" 2 980.5774 1.5 43364 8164 2 980.575714 491.296 Electron transfer flavoprotein subunit beta OS=Homo sapiens OX=9606 GN=ETFB PE=1 SV=3 8.59 1940.9 - 671455 - - - -1.7051 - 1.486 0.233 - 290.1 1 2 0 -0.0017 8 0 0 0 2.19E+07 1.46E+07 - - - 1.956 0.9298 221125_WJC_METTL3_EV_vs_WT_F04.08166.08166.2 2.46 18-Jul R.GSGLSMSAAR.S "sp|Q9Y618|NCOR2_HUMAN,tr|C9JQE8|C9JQE8_HUMAN,tr|C9JE98|C9JE98_HUMAN,tr|C9J330|C9J330_HUMAN,tr|C9J0Q5|C9J0Q5_HUMAN" 5 935.4495 8.89 43365 8166 2 935.446628 468.732 Nuclear receptor corepressor 2 OS=Homo sapiens OX=9606 GN=NCOR2 PE=1 SV=3 9.75 1941.1 - 834891 - - - -3.0328 - 1.092 0.155 - 124.8 2 2 0 -0.0028 10 0 0 0 2.67E+07 3.00E+06 - - - 0.2961 0.9998 221125_WJC_METTL3_EV_vs_WT_F04.08170.08170.2 0.019 14-Aug K.VC[160.03]FDC[160.03]GAK.N "sp|Q9NP61|ARFG3_HUMAN,tr|B0QYV9|B0QYV9_HUMAN,tr|B0QYV8|B0QYV8_HUMAN" 3 955.3892 1.17 43367 8170 2 955.388072 478.7019 ADP-ribosylation factor GTPase-activating protein 3 OS=Homo sapiens OX=9606 GN=ARFGAP3 PE=1 SV=1 5.79 1941.6 - 2.77E+06 - - - -1.1524 - 1.727 0.539 - 219.9 1 2 0 -0.0011 8 0 0 0 8.68E+07 7.44E+07 - - - 4.6696 0.9996 221125_WJC_METTL3_EV_vs_WT_F04.08171.08171.2 0.00102 14-Sep R.LTEGC[160.03]SFR[166.11].R "sp|Q71UM5|RS27L_HUMAN,sp|P42677|RS27_HUMAN,tr|H0YMV8|H0YMV8_HUMAN,tr|C9J1C5|C9J1C5_HUMAN" 4 978.4468 0.41 43368 8171 2 978.445876 490.2307 40S ribosomal protein S27-like OS=Homo sapiens OX=9606 GN=RPS27L PE=1 SV=3 5.99 1941.7 - 1.06E+06 - - - -0.9811 - 1.607 0.417 - 279.6 1 2 0 -0.001 8 0 0 0 3.88E+07 9.57E+07 - - - 3.5513 0.9913 221125_WJC_METTL3_EV_vs_WT_F04.08178.08178.2 2.97 12-Jun R.KNQIEIK.L "sp|Q9NYJ8|TAB2_HUMAN,tr|A0A1B0GV57|A0A1B0GV57_HUMAN" 2 871.5127 26.77 43373 8178 2 871.51126 436.7636 TGF-beta-activated kinase 1 and MAP3K7-binding protein 2 OS=Homo sapiens OX=9606 GN=TAB2 PE=1 SV=1 8.59 1942.6 - 952119 - - - -1.6718 - 1.673 0.076 - 200.5 2 2 0 -0.0015 7 0 0 0 2.02E+07 7.55E+05 - - - 1.098 0.9569 221125_WJC_METTL3_EV_vs_WT_F04.08182.08182.2 0.317 12-Jun K.INGDWQR[166.11].A "sp|P42704|LPPRC_HUMAN,tr|A0A804HI14|A0A804HI14_HUMAN,tr|A0A804HL40|A0A804HL40_HUMAN,tr|A0A804HKJ0|A0A804HKJ0_HUMAN,tr|A0A804HKR3|A0A804HKR3_HUMAN,tr|A0A804HIN4|A0A804HIN4_HUMAN,tr|A0A804HJG8|A0A804HJG8_HUMAN,tr|A0A804HLG8|A0A804HLG8_HUMAN,tr|A0A804HI40|A0A804HI40_HUMAN,tr|A0A804HJZ1|A0A804HJZ1_HUMAN,tr|A0A804HIQ7|A0A804HIQ7_HUMAN,tr|A0A804HK30|A0A804HK30_HUMAN,tr|A0A804HKI2|A0A804HKI2_HUMAN,tr|A0A804HJI0|A0A804HJI0_HUMAN,tr|A0A804HIG4|A0A804HIG4_HUMAN" 15 897.4332 0.9 43375 8182 2 897.429373 449.7239 "Leucine-rich PPR motif-containing protein, mitochondrial OS=Homo sapiens OX=9606 GN=LRPPRC PE=1 SV=3" 5.84 1943.1 - 1.79E+06 - - - -4.3034 - 1.325 0.184 - 96 1 2 0 -0.0039 7 0 0 0 5.50E+07 6.11E+07 - - - 1.2905 0.9998 221125_WJC_METTL3_EV_vs_WT_F04.08183.08183.2 6.55E-05 20-Oct R.LC[160.03]PNSTGAEIR[166.11].S "sp|P35998|PRS7_HUMAN,tr|C9JX88|C9JX88_HUMAN" 2 1226.5953 0.42 43376 8183 2 1226.5933 614.3049 26S proteasome regulatory subunit 7 OS=Homo sapiens OX=9606 GN=PSMC2 PE=1 SV=3 5.99 1943.2 - 1.06E+06 - - - -1.6232 - 1.924 0.512 - 355.8 1 2 0 -0.002 11 0 0 0 1.34E+07 3.20E+07 - - - 4.5923 0.9997 221125_WJC_METTL3_EV_vs_WT_F04.08189.08189.2 4.03E-05 16-Oct K.ESEFDDEPK.F "sp|Q9Y2W1|TR150_HUMAN,tr|A0A3B3ITZ9|A0A3B3ITZ9_HUMAN" 2 1094.4404 3.43 43378 8189 2 1094.43763 548.2275 Thyroid hormone receptor-associated protein 3 OS=Homo sapiens OX=9606 GN=THRAP3 PE=1 SV=2 3.83 1944.1 - 1.07E+07 - - - -2.531 - 1.759 0.59 - 426.3 1 2 0 -0.0028 9 0 0 0 7.83E+08 2.28E+08 - - - 5.0317 0.9448 221125_WJC_METTL3_EV_vs_WT_F04.08190.08190.2 0.309 18-Sep K.DAEIPEGAAR.G "sp|O14654|IRS4_HUMAN,tr|A0A804CF45|A0A804CF45_HUMAN" 2 1027.4934 0.83 43379 8190 2 1027.486201 514.754 Insulin receptor substrate 4 OS=Homo sapiens OX=9606 GN=IRS4 PE=1 SV=1 4.14 1944.1 - 4.18E+06 - - - -7.0434 - 1.682 0.29 - 310.7 1 2 0 -0.0072 10 0 0 0 2.19E+08 2.63E+08 - - - 2.6321 0.9914 221125_WJC_METTL3_EV_vs_WT_F04.08195.08195.2 0.00763 16-Jul K.NYEDEDSLK[136.11].T sp|P11388|TOP2A_HUMAN 1 1119.4811 0.96 43381 8195 2 1119.476305 560.7479 DNA topoisomerase 2-alpha OS=Homo sapiens OX=9606 GN=TOP2A PE=1 SV=3 3.92 1944.8 - 1.22E+06 - - - -4.327 - 1.257 0.399 - 130.4 1 2 0 -0.0048 9 0 0 0 1.84E+07 1.92E+07 - - - 2.6482 0.9435 221125_WJC_METTL3_EV_vs_WT_F04.08196.08196.2 5.19 14-Jul K.TADEVPLK[136.11].L sp|Q9NZI8|IF2B1_HUMAN 1 879.4793 2.02 43382 8196 2 879.475865 440.7469 Insulin-like growth factor 2 mRNA-binding protein 1 OS=Homo sapiens OX=9606 GN=IGF2BP1 PE=1 SV=2 4.37 1944.9 - 767372 - - - -3.9034 - 1.156 0.19 - 176.3 1 2 0 -0.0034 8 0 0 0 1.00E+08 4.96E+07 - - - 0.8805 0.9997 221125_WJC_METTL3_EV_vs_WT_F04.08199.08199.2 0.000571 16-Oct K.ESEFDDEPK[136.11].F "sp|Q9Y2W1|TR150_HUMAN,tr|A0A3B3ITZ9|A0A3B3ITZ9_HUMAN" 2 1102.4546 3.43 43383 8199 2 1102.453413 552.2346 Thyroid hormone receptor-associated protein 3 OS=Homo sapiens OX=9606 GN=THRAP3 PE=1 SV=2 3.83 1945.4 - 2.45E+06 - - - -1.0767 - 1.661 0.434 - 399.5 1 2 0 -0.0012 9 0 0 0 7.81E+08 2.28E+08 - - - 3.7141 0.849 221125_WJC_METTL3_EV_vs_WT_F04.08200.08200.2 0.00261 16-Oct K.QANPSVLER.D "sp|Q8NDD1|CA131_HUMAN,tr|Q5TBH9|Q5TBH9_HUMAN" 2 1012.5302 8.4 43384 8200 2 1012.522171 507.2724 Uncharacterized protein C1orf131 OS=Homo sapiens OX=9606 GN=C1orf131 PE=1 SV=4 6 1945.5 - 988059 - - - -7.8882 - 1.819 0.175 - 303.7 1 2 0 -0.008 9 0 0 0 2.18E+07 2.60E+06 - - - 2.0619 0.7803 221125_WJC_METTL3_EV_vs_WT_F04.08203.08203.2 0.0324 14-Aug L.QIDPSIQR.V "sp|P13647|K2C5_HUMAN,tr|F8W0C6|F8W0C6_HUMAN,tr|F8VU69|F8VU69_HUMAN" 3 955.5087 4 43385 8203 2 955.506119 478.7616 "Keratin, type II cytoskeletal 5 OS=Homo sapiens OX=9606 GN=KRT5 PE=1 SV=3" 5.84 1945.9 - 2.49E+06 - - - -2.6949 - 1.39 0.285 - 254 1 1 0 -0.0026 8 0 0 0 5.29E+07 1.32E+07 - - - 2.1384 0.9996 221125_WJC_METTL3_EV_vs_WT_F04.08205.08205.2 0.00184 18-Oct R.QIPQATASMK.D "sp|O43175|SERA_HUMAN,tr|A0A286YF78|A0A286YF78_HUMAN,tr|A0A2C9F2M7|A0A2C9F2M7_HUMAN,tr|A0A286YF22|A0A286YF22_HUMAN,tr|A0A286YFL2|A0A286YFL2_HUMAN,tr|A0A286YFA2|A0A286YFA2_HUMAN,tr|A0A286YFM8|A0A286YFM8_HUMAN,tr|A0A286YFE1|A0A286YFE1_HUMAN" 8 1073.5539 0.95 43387 8205 2 1073.552295 537.7842 D-3-phosphoglycerate dehydrogenase OS=Homo sapiens OX=9606 GN=PHGDH PE=1 SV=4 8.75 1946.1 - 3.13E+06 - - - -1.523 - 1.745 0.412 - 261.5 1 2 0 -0.0016 10 0 0 0 1.25E+08 1.32E+08 - - - 3.6376 0.9995 221125_WJC_METTL3_EV_vs_WT_F04.08206.08206.2 0.00223 18-Sep R.ISATTNLSER[166.11].Q "sp|P31271|HXA13_HUMAN,sp|P31276|HXC13_HUMAN" 2 1100.5701 1.59 43388 8206 2 1100.568394 551.2923 Homeobox protein Hox-A13 OS=Homo sapiens OX=9606 GN=HOXA13 PE=1 SV=3 6 1946.2 - 2.27E+06 - - - -1.5701 - 1.917 0.375 - 235.3 1 2 0 -0.0017 10 0 0 0 8.44E+07 5.31E+07 - - - 3.6267 0.9517 221125_WJC_METTL3_EV_vs_WT_F04.08207.08207.2 0.522 12-Jun R.INIPPQR.G "sp|Q13283|G3BP1_HUMAN,tr|A0A7I2V5M7|A0A7I2V5M7_HUMAN,tr|A0A7P0P2U7|A0A7P0P2U7_HUMAN,tr|A0A7I2YQU8|A0A7I2YQU8_HUMAN,tr|A0A7I2V548|A0A7I2V548_HUMAN,tr|A0A7I2V565|A0A7I2V565_HUMAN,tr|A0A7I2YQN9|A0A7I2YQN9_HUMAN" 7 836.4868 1.16 43389 8207 2 836.484126 419.2507 Ras GTPase-activating protein-binding protein 1 OS=Homo sapiens OX=9606 GN=G3BP1 PE=1 SV=1 9.75 1946.3 - 1.26E+06 - - - -3.2409 - 1.349 0.091 - 206.8 1 2 0 -0.0027 7 0 0 0 4.08E+07 3.52E+07 - - - 0.6608 0.999 221125_WJC_METTL3_EV_vs_WT_F04.08208.08208.2 0.0113 16-Aug K.NYEDEDSLK.T sp|P11388|TOP2A_HUMAN 1 1111.4669 1.11 43390 8208 2 1111.466088 556.7408 DNA topoisomerase 2-alpha OS=Homo sapiens OX=9606 GN=TOP2A PE=1 SV=3 3.92 1946.4 - 765508 - - - -0.7747 - 1.228 0.377 - 219.7 1 2 0 -0.0009 9 0 0 0 1.82E+07 1.64E+07 - - - 2.4194 0.9966 221125_WJC_METTL3_EV_vs_WT_F04.08212.08212.2 0.0703 12-Jul K.INGDWQR.A "sp|P42704|LPPRC_HUMAN,tr|A0A804HI14|A0A804HI14_HUMAN,tr|A0A804HL40|A0A804HL40_HUMAN,tr|A0A804HKJ0|A0A804HKJ0_HUMAN,tr|A0A804HKR3|A0A804HKR3_HUMAN,tr|A0A804HIN4|A0A804HIN4_HUMAN,tr|A0A804HJG8|A0A804HJG8_HUMAN,tr|A0A804HLG8|A0A804HLG8_HUMAN,tr|A0A804HI40|A0A804HI40_HUMAN,tr|A0A804HJZ1|A0A804HJZ1_HUMAN,tr|A0A804HIQ7|A0A804HIQ7_HUMAN,tr|A0A804HK30|A0A804HK30_HUMAN,tr|A0A804HKI2|A0A804HKI2_HUMAN,tr|A0A804HJI0|A0A804HJI0_HUMAN,tr|A0A804HIG4|A0A804HIG4_HUMAN" 15 887.425 0.91 43392 8212 2 887.422692 444.7198 "Leucine-rich PPR motif-containing protein, mitochondrial OS=Homo sapiens OX=9606 GN=LRPPRC PE=1 SV=3" 5.84 1946.9 - 1.91E+06 - - - -2.5613 - 1.415 0.295 - 136.6 1 2 0 -0.0023 7 0 0 0 5.57E+07 6.11E+07 - - - 2.3191 0.9992 221125_WJC_METTL3_EV_vs_WT_F04.08213.08213.2 0.000658 14-Aug R.LTEGC[160.03]SFR.R "sp|Q71UM5|RS27L_HUMAN,sp|P42677|RS27_HUMAN,tr|H0YMV8|H0YMV8_HUMAN,tr|C9J1C5|C9J1C5_HUMAN" 4 968.4386 0.41 43393 8213 2 968.436409 485.2266 40S ribosomal protein S27-like OS=Homo sapiens OX=9606 GN=RPS27L PE=1 SV=3 5.99 1947 - 2.17E+06 - - - -2.2273 - 1.691 0.39 - 200.9 1 2 0 -0.0022 8 0 0 0 3.88E+07 9.57E+07 - - - 3.5052 0.9309 221125_WJC_METTL3_EV_vs_WT_F04.08218.08218.2 0.212 14-Oct K.HAVNGFLK[136.11].E "sp|O75319|DUS11_HUMAN,tr|H7C0E6|H7C0E6_HUMAN" 2 892.501 2.47 43396 8218 2 892.49466 447.2578 RNA\RNP complex-1-interacting phosphatase OS=Homo sapiens OX=9606 GN=DUSP11 PE=1 SV=2 8.76 1947.6 - 1.80E+06 - - - -7.1451 - 1.913 0.2 - 305.8 1 2 0 -0.0064 8 0 0 0 5.95E+07 2.41E+07 - - - 2.4726 0.9426 221125_WJC_METTL3_EV_vs_WT_F04.08220.08220.2 6.88 12-Jun R.QQEEILR[166.11].R "sp|Q6Y7W6|GGYF2_HUMAN,sp|Q96DZ1|ERLEC_HUMAN,tr|A0A7I2V3H7|A0A7I2V3H7_HUMAN,tr|I1E4Y6|I1E4Y6_HUMAN,tr|A0A7I2V516|A0A7I2V516_HUMAN,tr|A0A7I2V3H0|A0A7I2V3H0_HUMAN,tr|C9JHW1|C9JHW1_HUMAN,tr|A0A7I2V361|A0A7I2V361_HUMAN,tr|E7ESB6|E7ESB6_HUMAN" 9 924.4904 1.69 43398 8220 2 924.48839 463.2525 GRB10-interacting GYF protein 2 OS=Homo sapiens OX=9606 GN=GIGYF2 PE=1 SV=1 4.53 1947.8 - 2.51E+06 - - - -2.1904 - 1.161 0.071 - 208.5 1 2 0 -0.002 7 0 0 0 1.22E+08 7.23E+07 - - - 0.0378 0.781 221125_WJC_METTL3_EV_vs_WT_F04.08221.08221.2 0.912 12-Jun R.EMFESQR[166.11].L sp|Q12948|FOXC1_HUMAN 1 935.4046 2.57 43399 8221 2 935.401193 468.7096 Forkhead box protein C1 OS=Homo sapiens OX=9606 GN=FOXC1 PE=1 SV=3 4.53 1947.8 - 1.66E+06 - - - -3.6818 - 1.058 0.074 - 154.2 1 2 0 -0.0034 7 0 0 0 1.53E+08 5.96E+07 - - - -0.2349 0.9999 221125_WJC_METTL3_EV_vs_WT_F04.08222.08222.2 7.04E-06 20-Dec R.VGSVLQEGC[160.03]GK[136.11].L "sp|P31040|SDHA_HUMAN,tr|A0A087X1I3|A0A087X1I3_HUMAN" 2 1140.5689 1.45 43400 8222 2 1140.568346 571.2917 "Succinate dehydrogenase [ubiquinone] flavoprotein subunit, mitochondrial OS=Homo sapiens OX=9606 GN=SDHA PE=1 SV=2" 5.97 1948 - 1.42E+06 - - - -0.4489 - 2.554 0.527 - 701.3 1 2 0 -0.0005 11 0 0 0 6.82E+07 4.70E+07 - - - 5.4699 1 221125_WJC_METTL3_EV_vs_WT_F04.08223.08223.2 2.51E-07 20-Dec R.VGSVLQEGC[160.03]GK.L "sp|P31040|SDHA_HUMAN,tr|A0A087X1I3|A0A087X1I3_HUMAN" 2 1132.5547 0.55 43401 8223 2 1132.557074 567.2846 "Succinate dehydrogenase [ubiquinone] flavoprotein subunit, mitochondrial OS=Homo sapiens OX=9606 GN=SDHA PE=1 SV=2" 5.97 1948.1 - 950492 - - - 2.1332 - 2.699 0.556 - 793.1 1 2 0 0.0024 11 0 0 0 2.09E+07 3.83E+07 - - - 5.8328 0.8149 221125_WJC_METTL3_EV_vs_WT_F04.08228.08228.2 0.793 12-May R.EMFESQR.L sp|Q12948|FOXC1_HUMAN 1 925.3964 3.14 43404 8228 2 925.394009 463.7055 Forkhead box protein C1 OS=Homo sapiens OX=9606 GN=FOXC1 PE=1 SV=3 4.53 1948.7 - 3.33E+06 - - - -2.5481 - 0.996 0.066 - 109.9 2 2 0 -0.0024 7 0 0 0 1.27E+08 4.05E+07 - - - -0.6194 0.8718 221125_WJC_METTL3_EV_vs_WT_F04.08230.08230.2 3.18 12-Aug K.AKDLILR.F "sp|Q9Y2H1|ST38L_HUMAN,sp|Q15208|STK38_HUMAN" 2 827.5229 3.29 43406 8230 2 827.520725 414.7687 Serine\threonine-protein kinase 38-like OS=Homo sapiens OX=9606 GN=STK38L PE=1 SV=3 8.79 1948.8 - 2.63E+06 - - - -2.6138 - 1.557 0.114 - 212.8 1 2 1 -0.0022 7 0 0 0 8.21E+07 2.49E+07 - - - 1.2852 0.9976 221125_WJC_METTL3_EV_vs_WT_F04.08237.08237.2 0.0933 14-Sep K.SLNDITAK.E "sp|P48047|ATPO_HUMAN,tr|H7C0C1|H7C0C1_HUMAN,tr|A0A494C0K9|A0A494C0K9_HUMAN" 3 860.4603 0.51 43411 8237 2 860.460228 431.2374 "ATP synthase subunit O, mitochondrial OS=Homo sapiens OX=9606 GN=ATP5PO PE=1 SV=1" 5.55 1949.7 - 1.78E+06 - - - -0.1383 - 1.449 0.199 - 225.5 1 2 0 -0.0001 8 0 0 0 8.95E+07 1.75E+08 - - - 1.6293 0.9991 221125_WJC_METTL3_EV_vs_WT_F04.08240.08240.2 9.58E-05 18-Sep R.FDDVTSEDTR[166.11].L "sp|Q9H6R0|DHX33_HUMAN,tr|I3L1L6|I3L1L6_HUMAN" 2 1193.5076 1.14 43414 8240 2 1193.502811 597.7611 ATP-dependent RNA helicase DHX33 OS=Homo sapiens OX=9606 GN=DHX33 PE=1 SV=2 3.84 1950.1 - 425813 - - - -3.9966 - 1.887 0.596 - 284.8 1 2 0 -0.0048 10 0 0 0 4.63E+06 4.04E+06 - - - 5.214 0.9991 221125_WJC_METTL3_EV_vs_WT_F04.08245.08245.2 1.46E-05 16-Oct R.MNEAFGDTK[136.11].F "sp|Q13263|TIF1B_HUMAN,tr|M0R0K9|M0R0K9_HUMAN" 2 1019.4473 1.25 43417 8245 2 1019.443318 510.7309 Transcription intermediary factor 1-beta OS=Homo sapiens OX=9606 GN=TRIM28 PE=1 SV=5 4.37 1950.8 - 3.41E+06 - - - -3.9512 - 2.007 0.553 - 404.3 1 2 0 -0.004 9 0 0 0 8.67E+07 6.95E+07 - - - 5.1396 0.9922 221125_WJC_METTL3_EV_vs_WT_F04.08247.08247.2 0.331 14-Sep K.HAVNGFLK.E "sp|O75319|DUS11_HUMAN,tr|H7C0E6|H7C0E6_HUMAN" 2 884.4868 2.51 43419 8247 2 884.483185 443.2507 RNA\RNP complex-1-interacting phosphatase OS=Homo sapiens OX=9606 GN=DUSP11 PE=1 SV=2 8.76 1950.9 - 1.85E+06 - - - -4.1289 - 1.753 0.254 - 242.5 1 2 0 -0.0037 8 0 0 0 6.12E+07 2.43E+07 - - - 2.6088 0.9998 221125_WJC_METTL3_EV_vs_WT_F04.08249.08249.2 0.000141 22-Nov R.ILQEDPTNTAAR[166.11].K "sp|Q15006|EMC2_HUMAN,tr|H0YAS9|H0YAS9_HUMAN" 2 1337.6815 2.54 43421 8249 2 1337.679652 669.848 ER membrane protein complex subunit 2 OS=Homo sapiens OX=9606 GN=EMC2 PE=1 SV=1 4.37 1951.2 - 553317 - - - -1.3538 - 2.28 0.451 - 366.1 1 2 0 -0.0018 12 0 0 0 6.79E+07 2.67E+07 - - - 4.5401 0.9996 221125_WJC_METTL3_EV_vs_WT_F04.08252.08252.2 0.000596 16-Sep R.MNEAFGDTK.F "sp|Q13263|TIF1B_HUMAN,tr|M0R0K9|M0R0K9_HUMAN" 2 1011.4331 0.86 43422 8252 2 1011.430953 506.7238 Transcription intermediary factor 1-beta OS=Homo sapiens OX=9606 GN=TRIM28 PE=1 SV=5 4.37 1951.6 - 3.29E+06 - - - -2.1682 - 1.798 0.473 - 245.3 1 2 0 -0.0022 9 0 0 0 5.84E+07 6.82E+07 - - - 4.2312 0.9995 221125_WJC_METTL3_EV_vs_WT_F04.08257.08257.2 7.42E-05 20-Oct K.FGTGGAAVPEK.L "sp|Q14241|ELOA1_HUMAN,tr|A0A024RAC6|A0A024RAC6_HUMAN" 2 1032.524 1.02 43425 8257 2 1032.526788 517.2693 Elongin-A OS=Homo sapiens OX=9606 GN=ELOA PE=1 SV=2 6 1952.2 - 1.27E+06 - - - 2.6905 - 2.252 0.45 - 276.5 1 2 0 0.0028 11 0 0 0 8.85E+07 8.70E+07 - - - 4.56 0.9993 221125_WJC_METTL3_EV_vs_WT_F04.08258.08258.2 0.0477 14-Oct K.TLLVNNNR[166.11].L "sp|P09661|RU2A_HUMAN,tr|H0YKK0|H0YKK0_HUMAN" 2 952.5329 1.2 43426 8258 2 952.534553 477.2738 U2 small nuclear ribonucleoprotein A' OS=Homo sapiens OX=9606 GN=SNRPA1 PE=1 SV=2 9.41 1952.3 - 669427 - - - 1.6839 - 1.632 0.376 - 356.6 1 2 0 0.0016 8 0 0 0 1.61E+07 1.34E+07 - - - 3.2949 0.9974 221125_WJC_METTL3_EV_vs_WT_F04.08259.08259.2 0.308 14-Jul R.AC[160.03]YEESLK[136.11].S "sp|Q9Y618|NCOR2_HUMAN,tr|C9J7T7|C9J7T7_HUMAN,tr|C9JE98|C9JE98_HUMAN,tr|C9J0Q5|C9J0Q5_HUMAN,tr|A0A384DVL6|A0A384DVL6_HUMAN" 5 1006.4521 3.23 43427 8259 2 1006.452108 504.2333 Nuclear receptor corepressor 2 OS=Homo sapiens OX=9606 GN=NCOR2 PE=1 SV=3 4.53 1952.3 - 2.84E+06 - - - 0.0109 - 1.373 0.215 - 208.9 1 2 0 0 8 0 0 0 4.17E+07 1.29E+07 - - - 1.585 0.9992 221125_WJC_METTL3_EV_vs_WT_F04.08260.08260.2 0.00107 24-Dec R.EVATNSELVQSGK.S "sp|Q04695|K1C17_HUMAN,sp|P02533|K1C14_HUMAN,tr|K7ESE1|K7ESE1_HUMAN,tr|F5GWP8|F5GWP8_HUMAN" 4 1360.6834 999 43428 8260 2 1360.679252 681.349 "Keratin, type I cytoskeletal 17 OS=Homo sapiens OX=9606 GN=KRT17 PE=1 SV=2" 4.53 1952.5 - 402977 - - - -3.0661 - 1.898 0.496 - 216.1 1 2 0 -0.0042 13 0 0 0 6.15E+06 0.00E+00 - - - 4.3478 0.9998 221125_WJC_METTL3_EV_vs_WT_F04.08261.08261.2 7.27E-05 22-Sep K.IAPAEGPDVSER.M "sp|Q9Y6M1|IF2B2_HUMAN,tr|F8W930|F8W930_HUMAN" 2 1239.6095 2.4 43429 8261 2 1239.609017 620.812 Insulin-like growth factor 2 mRNA-binding protein 2 OS=Homo sapiens OX=9606 GN=IGF2BP2 PE=1 SV=2 4.14 1952.6 - 265340 - - - -0.4146 - 1.775 0.533 - 263.9 1 2 0 -0.0005 12 0 0 0 1.56E+08 6.48E+07 - - - 4.4873 0.9987 221125_WJC_METTL3_EV_vs_WT_F04.08265.08265.2 0.054 14-Jul K.GANPVEIR.R "sp|P10809|CH60_HUMAN,tr|A0A7I2V2X6|A0A7I2V2X6_HUMAN,tr|A0A7I2YQK6|A0A7I2YQK6_HUMAN,tr|A0A7I2V599|A0A7I2V599_HUMAN,tr|E7EXB4|E7EXB4_HUMAN,tr|A0A7I2YQ71|A0A7I2YQ71_HUMAN,tr|E7ESH4|E7ESH4_HUMAN,tr|A0A7I2V5M1|A0A7I2V5M1_HUMAN,tr|A0A7I2V5K3|A0A7I2V5K3_HUMAN,tr|A0A7I2V369|A0A7I2V369_HUMAN" 10 854.461 1.28 43431 8265 2 854.460059 428.2378 "60 kDa heat shock protein, mitochondrial OS=Homo sapiens OX=9606 GN=HSPD1 PE=1 SV=2" 6 1953.1 - 1.82E+06 - - - -1.12 - 1.44 0.297 - 270.5 1 2 0 -0.001 8 0 0 0 2.50E+09 1.96E+09 - - - 2.3341 0.9985 221125_WJC_METTL3_EV_vs_WT_F04.08267.08267.2 0.188 14-Aug K.AEFAEVSK.L "sp|P02768|ALBU_HUMAN,tr|B7WNR0|B7WNR0_HUMAN,tr|H0YA55|H0YA55_HUMAN,tr|A0A0C4DGB6|A0A0C4DGB6_HUMAN,tr|D6RHD5|D6RHD5_HUMAN,tr|C9JKR2|C9JKR2_HUMAN" 6 879.4338 7.46 43433 8267 2 879.434325 440.7242 Albumin OS=Homo sapiens OX=9606 GN=ALB PE=1 SV=2 4.53 1953.2 - 1.82E+06 - - - 0.5992 - 1.469 0.262 - 267.7 1 2 0 0.0005 8 0 0 0 4.77E+07 6.39E+06 - - - 2.1358 0.9995 221125_WJC_METTL3_EV_vs_WT_F04.08269.08269.2 0.000613 14-Jul R.ASYDDPYK[136.11].K sp|Q96PK6|RBM14_HUMAN 1 965.4222 2.07 43435 8269 2 965.421341 483.7184 RNA-binding protein 14 OS=Homo sapiens OX=9606 GN=RBM14 PE=1 SV=2 4.21 1953.4 - 910667 - - - -0.8659 - 1.504 0.402 - 186.4 1 2 0 -0.0008 8 0 0 0 2.88E+08 1.39E+08 - - - 3.2408 0.9775 221125_WJC_METTL3_EV_vs_WT_F04.08274.08274.2 3.93 12-Jun K.SFENISK[136.11].W sp|P61026|RAB10_HUMAN 1 831.4218 1.14 43438 8274 2 831.420973 416.7182 Ras-related protein Rab-10 OS=Homo sapiens OX=9606 GN=RAB10 PE=1 SV=1 5.72 1954.1 - 2.80E+06 - - - -0.9742 - 1.107 0.112 - 122.5 1 2 0 -0.0008 7 0 0 0 9.13E+07 8.03E+07 - - - 0.1901 0.9938 221125_WJC_METTL3_EV_vs_WT_F04.08275.08275.2 6.05 12-Jun K.SFENISK.W sp|P61026|RAB10_HUMAN 1 823.4076 1.15 43439 8275 2 823.406526 412.7111 Ras-related protein Rab-10 OS=Homo sapiens OX=9606 GN=RAB10 PE=1 SV=1 5.72 1954.2 - 2.72E+06 - - - -1.2837 - 1.256 0.191 - 123.4 1 2 0 -0.0011 7 0 0 0 8.93E+07 7.74E+07 - - - 1.1736 0.9177 221125_WJC_METTL3_EV_vs_WT_F04.08276.08276.2 0.00266 20-Oct K.IANPVEGSTDR.Q "sp|Q15366|PCBP2_HUMAN,tr|F8VRH0|F8VRH0_HUMAN,tr|F8VZX2|F8VZX2_HUMAN,tr|H3BRU6|H3BRU6_HUMAN,tr|H3BSS4|H3BSS4_HUMAN" 5 1157.5677 1.84 43440 8276 2 1158.567232 579.7911 Poly(rC)-binding protein 2 OS=Homo sapiens OX=9606 GN=PCBP2 PE=1 SV=1 4.37 1954.3 - 2.05E+06 - - - 863.5055 - 1.947 0.369 - 208.8 1 2 0 0.9996 11 0 0 0 9.47E+07 5.14E+07 - - - 3.255 0.9997 221125_WJC_METTL3_EV_vs_WT_F04.08279.08279.2 0.00502 20-Dec K.IANPVEGSTDR[166.11].Q "sp|Q15366|PCBP2_HUMAN,tr|F8VRH0|F8VRH0_HUMAN,tr|F8VZX2|F8VZX2_HUMAN,tr|H3BRU6|H3BRU6_HUMAN,tr|H3BSS4|H3BSS4_HUMAN" 5 1167.5759 1.85 43443 8279 2 1167.576078 584.7952 Poly(rC)-binding protein 2 OS=Homo sapiens OX=9606 GN=PCBP2 PE=1 SV=1 4.37 1954.5 - 550010 - - - 0.1216 - 2.134 0.343 - 525 1 2 0 0.0001 11 0 0 0 9.49E+07 5.14E+07 - - - 3.6249 0.9991 221125_WJC_METTL3_EV_vs_WT_F04.08280.08280.2 0.00233 22-Sep K.YVGETQPTGQIK.L "sp|Q9Y3Z3|SAMH1_HUMAN,tr|A0A2R8YCS7|A0A2R8YCS7_HUMAN" 2 1319.6721 0.7 43444 8280 2 1319.669134 660.8433 Deoxynucleoside triphosphate triphosphohydrolase SAMHD1 OS=Homo sapiens OX=9606 GN=SAMHD1 PE=1 SV=2 6 1954.6 - 506639 - - - -2.271 - 1.554 0.44 - 182.9 1 2 0 -0.003 12 0 0 0 1.34E+07 1.93E+07 - - - 3.4498 0.999 221125_WJC_METTL3_EV_vs_WT_F04.08285.08285.2 0.193 16-Jul K.TAQGSLSLK.A "sp|O15372|EIF3H_HUMAN,tr|B3KS98|B3KS98_HUMAN,tr|A0A087WZK9|A0A087WZK9_HUMAN,tr|E5RGU4|E5RGU4_HUMAN,tr|E5RJT0|E5RJT0_HUMAN" 5 903.5025 1.79 43447 8285 2 903.501826 452.7585 Eukaryotic translation initiation factor 3 subunit H OS=Homo sapiens OX=9606 GN=EIF3H PE=1 SV=1 8.41 1955.3 - 9.45E+06 - - - -0.7969 - 1.424 0.329 - 168 1 2 0 -0.0007 9 0 0 0 9.41E+08 5.26E+08 - - - 2.4934 0.9983 221125_WJC_METTL3_EV_vs_WT_F04.08286.08286.2 0.00548 16-Aug K.TAQGSLSLK[136.11].A "sp|O15372|EIF3H_HUMAN,tr|B3KS98|B3KS98_HUMAN,tr|A0A087WZK9|A0A087WZK9_HUMAN,tr|E5RGU4|E5RGU4_HUMAN,tr|E5RJT0|E5RJT0_HUMAN" 5 911.5167 1.79 43448 8286 2 911.515994 456.7656 Eukaryotic translation initiation factor 3 subunit H OS=Homo sapiens OX=9606 GN=EIF3H PE=1 SV=1 8.41 1955.4 - 6.92E+06 - - - -0.825 - 1.561 0.23 - 203.1 1 2 0 -0.0008 9 0 0 0 9.41E+08 5.26E+08 - - - 2.0279 0.9996 221125_WJC_METTL3_EV_vs_WT_F04.08287.08287.2 0.000796 14-Jul K.GANPVEIR[166.11].R "sp|P10809|CH60_HUMAN,tr|A0A7I2V2X6|A0A7I2V2X6_HUMAN,tr|A0A7I2YQK6|A0A7I2YQK6_HUMAN,tr|A0A7I2V599|A0A7I2V599_HUMAN,tr|E7EXB4|E7EXB4_HUMAN,tr|A0A7I2YQ71|A0A7I2YQ71_HUMAN,tr|E7ESH4|E7ESH4_HUMAN,tr|A0A7I2V5M1|A0A7I2V5M1_HUMAN,tr|A0A7I2V5K3|A0A7I2V5K3_HUMAN,tr|A0A7I2V369|A0A7I2V369_HUMAN" 10 864.4693 1.28 43449 8287 2 864.468821 433.2419 "60 kDa heat shock protein, mitochondrial OS=Homo sapiens OX=9606 GN=HSPD1 PE=1 SV=2" 6 1955.4 - 6.66E+06 - - - -0.5379 - 1.746 0.358 - 268.6 1 2 0 -0.0005 8 0 0 0 2.50E+09 1.96E+09 - - - 3.3659 0.9746 221125_WJC_METTL3_EV_vs_WT_F04.08289.08289.2 0.828 12-May K.QQEEVFR.N sp|Q7L4I2|RSRC2_HUMAN 1 934.4508 1.02 43451 8289 2 934.449323 468.2327 Arginine\serine-rich coiled-coil protein 2 OS=Homo sapiens OX=9606 GN=RSRC2 PE=1 SV=1 4.53 1955.6 - 1.41E+06 - - - -1.6288 - 1.154 0.114 - 144.8 1 2 0 -0.0015 7 0 0 0 5.32E+07 5.21E+07 - - - 0.3364 0.9998 221125_WJC_METTL3_EV_vs_WT_F04.08290.08290.2 0.002 18-Oct R.EGELTVAQGR[166.11].V sp|Q03252|LMNB2_HUMAN 1 1068.5439 1.26 43452 8290 2 1068.54432 535.2792 Lamin-B2 OS=Homo sapiens OX=9606 GN=LMNB2 PE=1 SV=4 4.53 1955.7 - 1.04E+06 - - - 0.3865 - 2.191 0.387 - 562.6 1 2 0 0.0004 10 0 0 0 9.68E+07 7.71E+07 - - - 4.0886 0.9977 221125_WJC_METTL3_EV_vs_WT_F04.08291.08291.2 0.0426 12-Aug R.HPSLAFK[136.11].A "sp|O94952|FBX21_HUMAN,tr|Q4G104|Q4G104_HUMAN,tr|H0YIE9|H0YIE9_HUMAN" 3 806.453 0.31 43453 8291 2 806.451957 404.2338 F-box only protein 21 OS=Homo sapiens OX=9606 GN=FBXO21 PE=2 SV=2 8.76 1955.8 - 619208 - - - -1.3231 - 1.327 0.273 - 175.1 1 2 0 -0.0011 7 0 0 0 4.01E+06 1.29E+07 - - - 1.9535 0.9877 221125_WJC_METTL3_EV_vs_WT_F04.08295.08295.2 2.38 12-May K.HGSFLVR.E "sp|Q06124|PTN11_HUMAN,tr|A0A1W2PPU4|A0A1W2PPU4_HUMAN" 2 814.445 0.51 43455 8295 2 814.444357 408.2298 Tyrosine-protein phosphatase non-receptor type 11 OS=Homo sapiens OX=9606 GN=PTPN11 PE=1 SV=3 9.76 1956.3 - 350692 - - - -0.7551 - 1.06 0.178 - 66.3 1 2 0 -0.0006 7 0 0 0 6.45E+06 1.25E+07 - - - 0.5401 0.9986 221125_WJC_METTL3_EV_vs_WT_F04.08298.08298.2 0.0445 16-Aug K.ETGVPIAGR.H "sp|P11586|C1TC_HUMAN,tr|F5H2F4|F5H2F4_HUMAN,tr|V9GZ78|V9GZ78_HUMAN,tr|V9GYY3|V9GYY3_HUMAN" 4 898.4872 1.8 43458 8298 2 898.485968 450.2509 "C-1-tetrahydrofolate synthase, cytoplasmic OS=Homo sapiens OX=9606 GN=MTHFD1 PE=1 SV=4" 6.1 1956.6 - 1.26E+06 - - - -1.4046 - 1.606 0.27 - 214.7 1 2 0 -0.0013 9 0 0 0 5.65E+07 3.13E+07 - - - 2.4054 0.9571 221125_WJC_METTL3_EV_vs_WT_F04.08299.08299.2 0.00752 16-Jul V.VLIGGK[136.11]PDR[166.11].V "sp|P61978|HNRPK_HUMAN,tr|Q5T6W2|Q5T6W2_HUMAN" 2 971.5883 1.19 43459 8299 2 971.588468 486.8014 Heterogeneous nuclear ribonucleoprotein K OS=Homo sapiens OX=9606 GN=HNRNPK PE=1 SV=1 8.72 1956.6 - 488246 - - - 0.1884 - 1.369 0.366 - 178.2 1 1 0 0.0002 9 0 0 0 4.10E+07 3.46E+07 - - - 2.6529 0.9997 221125_WJC_METTL3_EV_vs_WT_F04.08303.08303.2 1.75E-05 18-Sep R.EGELTVAQGR.V sp|Q03252|LMNB2_HUMAN 1 1058.5356 1.24 43461 8303 2 1058.535469 530.2751 Lamin-B2 OS=Homo sapiens OX=9606 GN=LMNB2 PE=1 SV=4 4.53 1957.2 - 2.58E+06 - - - -0.1587 - 2.238 0.332 - 428.2 1 2 0 -0.0002 10 0 0 0 9.56E+07 7.69E+07 - - - 3.7417 0.9954 221125_WJC_METTL3_EV_vs_WT_F04.08309.08309.2 0.0381 12-Jun R.INIPPQR[166.11].G "sp|Q13283|G3BP1_HUMAN,tr|A0A7I2V5M7|A0A7I2V5M7_HUMAN,tr|A0A7P0P2U7|A0A7P0P2U7_HUMAN,tr|A0A7I2YQU8|A0A7I2YQU8_HUMAN,tr|A0A7I2V548|A0A7I2V548_HUMAN,tr|A0A7I2V565|A0A7I2V565_HUMAN,tr|A0A7I2YQN9|A0A7I2YQN9_HUMAN" 7 846.4951 1.37 43465 8309 2 846.495726 424.2548 Ras GTPase-activating protein-binding protein 1 OS=Homo sapiens OX=9606 GN=G3BP1 PE=1 SV=1 9.75 1957.9 - 1.19E+06 - - - 0.7313 - 1.443 0.146 - 161.7 1 2 0 0.0006 7 0 0 0 5.61E+07 4.09E+07 - - - 1.2811 0.9997 221125_WJC_METTL3_EV_vs_WT_F04.08311.08311.2 0.0121 18-Aug R.SLQSENAALR[166.11].L "sp|Q13948|CASP_HUMAN,sp|P39880|CUX1_HUMAN,tr|A0A2R8Y852|A0A2R8Y852_HUMAN,tr|A0A2R8YDI1|A0A2R8YDI1_HUMAN" 4 1097.5705 1.57 43467 8311 2 1097.570208 549.7925 Protein CASP OS=Homo sapiens OX=9606 GN=CUX1 PE=1 SV=2 5.72 1958.1 - 2.20E+06 - - - -0.226 - 1.918 0.372 - 196.5 1 2 0 -0.0002 10 0 0 0 2.38E+08 1.51E+08 - - - 3.6064 0.9996 221125_WJC_METTL3_EV_vs_WT_F04.08312.08312.2 5.66E-06 16-Nov K.C[160.03]AMTALSSK[136.11].L sp|Q99832|TCPH_HUMAN 1 975.4609 0.29 43468 8312 2 975.458873 488.7377 T-complex protein 1 subunit eta OS=Homo sapiens OX=9606 GN=CCT7 PE=1 SV=2 8.22 1958.2 - 1.86E+06 - - - -2.0657 - 1.693 0.502 - 317.4 1 2 0 -0.002 9 0 0 0 7.83E+07 2.67E+08 - - - 4.2713 0.997 221125_WJC_METTL3_EV_vs_WT_F04.08318.08318.2 0.00324 18-Aug R.VVLIGGKPDR.V "sp|P61978|HNRPK_HUMAN,tr|Q5T6W2|Q5T6W2_HUMAN" 2 1052.6342 1.26 43471 8318 2 1052.633577 527.3244 Heterogeneous nuclear ribonucleoprotein K OS=Homo sapiens OX=9606 GN=HNRNPK PE=1 SV=1 8.72 1958.9 - 1.86E+06 - - - -0.6194 - 1.753 0.124 - 288.8 1 2 0 -0.0007 10 0 0 0 7.67E+07 6.10E+07 - - - 1.5235 0.8808 221125_WJC_METTL3_EV_vs_WT_F04.08320.08320.2 3.48 12-Jun K.TELNLSK[136.11].G sp|Q5W0B1|OBI1_HUMAN 1 811.4531 0.7 43473 8320 2 811.450772 406.7338 ORC ubiquitin ligase 1 OS=Homo sapiens OX=9606 GN=OBI1 PE=1 SV=1 5.66 1959.1 - 301535 - - - -2.848 - 1.156 0.064 - 126.3 2 2 0 -0.0023 7 0 0 0 1.62E+07 2.30E+07 - - - -0.1622 0.9997 221125_WJC_METTL3_EV_vs_WT_F04.08326.08326.2 0.266 18-Oct K.AAAEQAISVR.Q sp|Q01780|EXOSX_HUMAN 1 1014.5458 1.28 43477 8326 2 1014.545496 508.2802 Exosome component 10 OS=Homo sapiens OX=9606 GN=EXOSC10 PE=1 SV=2 6.05 1959.8 - 884710 - - - -0.3075 - 2.233 0.301 - 471.9 1 2 0 -0.0003 10 0 0 0 9.19E+07 7.16E+07 - - - 3.5065 0.9997 221125_WJC_METTL3_EV_vs_WT_F04.08327.08327.2 0.0106 18-Nov K.AAAEQAISVR[166.11].Q sp|Q01780|EXOSX_HUMAN 1 1024.5541 1.31 43478 8327 2 1024.553022 513.2843 Exosome component 10 OS=Homo sapiens OX=9606 GN=EXOSC10 PE=1 SV=2 6.05 1959.9 - 706749 - - - -1.0307 - 2.16 0.365 - 293.2 1 2 0 -0.0011 10 0 0 0 9.18E+07 7.00E+07 - - - 3.8862 0.8337 221125_WJC_METTL3_EV_vs_WT_F04.08328.08328.2 0.611 12-Jul K.TELNLSK.G sp|Q5W0B1|OBI1_HUMAN 1 803.4389 0.65 43479 8328 2 803.435424 402.7267 ORC ubiquitin ligase 1 OS=Homo sapiens OX=9606 GN=OBI1 PE=1 SV=1 5.66 1960.1 - 339093 - - - -4.3052 - 1.341 0.041 - 231.5 1 2 0 -0.0035 7 0 0 0 1.55E+07 2.39E+07 - - - 0.2724 0.9487 221125_WJC_METTL3_EV_vs_WT_F04.08339.08339.2 0.517 12-Jul R.TQNLEIR[166.11].E "sp|Q7Z353|HDX_HUMAN,tr|E2QRN0|E2QRN0_HUMAN" 2 882.4799 2.6 43486 8339 2 882.477455 442.2472 Highly divergent homeobox OS=Homo sapiens OX=9606 GN=HDX PE=1 SV=1 5.66 1961.5 - 592118 - - - -2.7139 - 1.298 0.067 - 185.9 1 2 0 -0.0024 7 0 0 0 4.66E+07 1.80E+07 - - - 0.3615 0.9998 221125_WJC_METTL3_EV_vs_WT_F04.08343.08343.2 0.00188 18-Sep R.ATAFNEQVDK[136.11].F sp|P27694|RFA1_HUMAN 1 1129.5495 1.34 43488 8343 2 1129.548729 565.782 Replication protein A 70 kDa DNA-binding subunit OS=Homo sapiens OX=9606 GN=RPA1 PE=1 SV=2 4.37 1961.9 - 2.15E+06 - - - -0.6852 - 1.928 0.467 - 363.7 1 2 0 -0.0008 10 0 0 0 1.02E+08 7.58E+07 - - - 4.3225 0.9981 221125_WJC_METTL3_EV_vs_WT_F04.08353.08353.2 0.265 12-Jul R.FSGVPDR.F "sp|A0A075B6R9|KVD24_HUMAN,sp|A0A0C4DH68|KV224_HUMAN,sp|A2NJV5|KV229_HUMAN,sp|A0A075B6S2|KVD29_HUMAN,sp|A0A0A0MRZ7|KVD26_HUMAN" 5 776.3817 314.52 43495 8353 2 776.380319 389.1981 Probable non-functional immunoglobulin kappa variable 2D-24 OS=Homo sapiens OX=9606 GN=IGKV2D-24 PE=1 SV=1 5.84 1963 - 2.33E+06 - - - -1.7826 - 1.501 0.276 - 160.2 1 2 0 -0.0014 7 0 0 0 7.56E+07 2.40E+05 - - - 2.366 0.9998 221125_WJC_METTL3_EV_vs_WT_F04.08355.08355.2 0.00021 18-Aug R.ATAFNEQVDK.F sp|P27694|RFA1_HUMAN 1 1121.5353 1.31 43496 8355 2 1121.534064 561.7749 Replication protein A 70 kDa DNA-binding subunit OS=Homo sapiens OX=9606 GN=RPA1 PE=1 SV=2 4.37 1963.2 - 2.79E+06 - - - -1.1047 - 1.963 0.48 - 258.4 1 2 0 -0.0012 10 0 0 0 1.02E+08 7.75E+07 - - - 4.4686 0.9986 221125_WJC_METTL3_EV_vs_WT_F04.08360.08360.2 0.203 18-Aug R.VVLIGGK[136.11]PDR[166.11].V "sp|P61978|HNRPK_HUMAN,tr|Q5T6W2|Q5T6W2_HUMAN" 2 1070.6567 1.26 43499 8360 2 1070.656335 536.3356 Heterogeneous nuclear ribonucleoprotein K OS=Homo sapiens OX=9606 GN=HNRNPK PE=1 SV=1 8.72 1963.7 - 1.37E+06 - - - -0.34 - 1.711 0.21 - 284 1 2 0 -0.0004 10 0 0 0 7.67E+07 6.10E+07 - - - 2.0911 0.9963 221125_WJC_METTL3_EV_vs_WT_F04.08362.08362.2 0.577 16-Oct K.ELEEIQSEK.E "sp|Q8IWJ2|GCC2_HUMAN,tr|U3KPU4|U3KPU4_HUMAN,tr|U3KQE0|U3KQE0_HUMAN,tr|B8ZZW2|B8ZZW2_HUMAN" 4 1103.5346 0.97 43501 8362 2 1103.536943 552.7746 GRIP and coiled-coil domain-containing protein 2 OS=Homo sapiens OX=9606 GN=GCC2 PE=1 SV=4 4.09 1963.9 - 434930 - - - 2.0924 - 1.718 0.193 - 401.5 1 2 0 0.0023 9 0 0 0 9.30E+06 9.60E+06 - - - 2.0314 0.9998 221125_WJC_METTL3_EV_vs_WT_F04.08365.08365.2 1.03E-05 20-Oct R.VAVEEVDEEGK[136.11].F "sp|P02545|LMNA_HUMAN,tr|A0A804HL68|A0A804HL68_HUMAN,tr|Q5TCI8|Q5TCI8_HUMAN,tr|A0A6Q8PFJ0|A0A6Q8PFJ0_HUMAN,tr|A0A6Q8PHQ9|A0A6Q8PHQ9_HUMAN" 5 1210.5809 1.65 43502 8365 2 1210.579374 606.2977 Prelamin-A\C OS=Homo sapiens OX=9606 GN=LMNA PE=1 SV=1 3.91 1964.3 - 201368 - - - -1.23 - 1.815 0.558 - 319.6 1 2 0 -0.0015 11 0 0 0 2.27E+07 1.37E+07 - - - 4.7745 0.9982 221125_WJC_METTL3_EV_vs_WT_F04.08369.08369.2 0.0492 14-Jul K.DSSLGLSK[136.11].E sp|O00443|P3C2A_HUMAN 1 813.4323 1.17 43505 8369 2 813.431599 407.7235 Phosphatidylinositol 4-phosphate 3-kinase C2 domain-containing subunit alpha OS=Homo sapiens OX=9606 GN=PIK3C2A PE=1 SV=2 5.84 1964.8 - 703976 - - - -0.9208 - 1.548 0.22 - 226.8 1 2 0 -0.0007 8 0 0 0 2.89E+07 2.47E+07 - - - 1.9835 0.9994 221125_WJC_METTL3_EV_vs_WT_F04.08371.08371.2 0.0584 18-Aug R.SLQSENAALR.L "sp|Q13948|CASP_HUMAN,sp|P39880|CUX1_HUMAN,tr|A0A2R8Y852|A0A2R8Y852_HUMAN,tr|A0A2R8YDI1|A0A2R8YDI1_HUMAN" 4 1087.5622 1.57 43506 8371 2 1087.561336 544.7884 Protein CASP OS=Homo sapiens OX=9606 GN=CUX1 PE=1 SV=2 5.72 1965 - 6.54E+06 - - - -0.7816 - 1.795 0.309 - 182.4 1 2 0 -0.0008 10 0 0 0 2.38E+08 1.51E+08 - - - 2.9559 0.9964 221125_WJC_METTL3_EV_vs_WT_F04.08373.08373.2 0.0533 14-Jun R.ELTAVVQK[136.11].R "sp|P23396|RS3_HUMAN,tr|E9PL09|E9PL09_HUMAN,tr|E9PK82|E9PK82_HUMAN,tr|F2Z2S8|F2Z2S8_HUMAN,tr|H0YCJ7|H0YCJ7_HUMAN,tr|E9PQ96|E9PQ96_HUMAN,tr|E9PJH4|E9PJH4_HUMAN,tr|E9PPU1|E9PPU1_HUMAN,tr|H0YF32|H0YF32_HUMAN" 9 894.5266 0.76 43507 8373 2 894.525132 448.2706 40S ribosomal protein S3 OS=Homo sapiens OX=9606 GN=RPS3 PE=1 SV=2 6.1 1965.2 - 1.48E+06 - - - -1.6221 - 1.424 0.219 - 183.8 1 2 0 -0.0014 8 0 0 0 4.38E+07 5.76E+07 - - - 1.7241 0.9981 221125_WJC_METTL3_EV_vs_WT_F04.08374.08374.2 0.0405 14-Jul K.DSSLGLSK.E sp|O00443|P3C2A_HUMAN 1 805.4181 1.14 43508 8374 2 805.417856 403.7164 Phosphatidylinositol 4-phosphate 3-kinase C2 domain-containing subunit alpha OS=Homo sapiens OX=9606 GN=PIK3C2A PE=1 SV=2 5.84 1965.4 - 675754 - - - -0.3625 - 1.556 0.197 - 285.7 1 2 0 -0.0003 8 0 0 0 2.70E+07 2.37E+07 - - - 1.8294 0.7882 221125_WJC_METTL3_EV_vs_WT_F04.08375.08375.2 1.27 14-May K.YHPGYFGK.V "sp|P46776|RL27A_HUMAN,tr|E9PLL6|E9PLL6_HUMAN" 2 967.4552 0.39 43509 8375 2 967.452911 484.7349 60S ribosomal protein L27a OS=Homo sapiens OX=9606 GN=RPL27A PE=1 SV=2 8.5 1965.4 - 3.16E+06 - - - -2.3681 - 0.991 0.043 - 91.3 2 2 0 -0.0023 8 0 0 0 8.90E+07 2.31E+08 - - - -0.8039 0.9996 221125_WJC_METTL3_EV_vs_WT_F04.08376.08376.2 0.00439 20-Oct R.VAVEEVDEEGK.F "sp|P02545|LMNA_HUMAN,tr|A0A804HL68|A0A804HL68_HUMAN,tr|Q5TCI8|Q5TCI8_HUMAN,tr|A0A6Q8PFJ0|A0A6Q8PFJ0_HUMAN,tr|A0A6Q8PHQ9|A0A6Q8PHQ9_HUMAN" 5 1202.5667 1.65 43510 8376 2 1202.565006 602.2906 Prelamin-A\C OS=Homo sapiens OX=9606 GN=LMNA PE=1 SV=1 3.91 1965.5 - 409469 - - - -1.3779 - 1.784 0.412 - 305.3 1 2 0 -0.0017 11 0 0 0 2.27E+07 1.37E+07 - - - 3.6495 0.9998 221125_WJC_METTL3_EV_vs_WT_F04.08381.08381.2 0.000166 20-Nov R.LGGPQASLSTK[136.11].V "sp|Q9NUI1|DECR2_HUMAN,tr|Q4VXZ8|Q4VXZ8_HUMAN" 2 1065.591 0.98 43513 8381 2 1065.590051 533.8028 "Peroxisomal 2,4-dienoyl-CoA reductase [(3E)-enoyl-CoA-producing] OS=Homo sapiens OX=9606 GN=DECR2 PE=1 SV=1" 8.75 1966.2 - 534343 - - - -0.8662 - 1.976 0.447 - 347.3 1 2 0 -0.0009 11 0 0 0 1.88E+07 1.91E+07 - - - 4.1847 0.9916 221125_WJC_METTL3_EV_vs_WT_F04.08382.08382.3 0.0151 Sep-36 R.FRELAEEAAR.L sp|Q15149|PLEC_HUMAN 1 1190.6044 1.4 43514 8382 3 1190.604381 397.8754 Plectin OS=Homo sapiens OX=9606 GN=PLEC PE=1 SV=3 4.79 1966.4 - 221390 - - - -0.0042 - 1.682 0.254 - 148.3 1 2 1 0 10 0 0 0 3.10E+06 2.22E+06 - - - 2.8904 0.9995 221125_WJC_METTL3_EV_vs_WT_F04.08385.08385.2 0.0189 16-Jul R.ANGMELDGR.R "sp|P62995|TRA2B_HUMAN,sp|Q13595|TRA2A_HUMAN,tr|H7BXF3|H7BXF3_HUMAN" 3 961.4287 2.28 43515 8385 2 961.428013 481.7216 Transformer-2 protein homolog beta OS=Homo sapiens OX=9606 GN=TRA2B PE=1 SV=1 4.37 1966.8 - 5.86E+06 - - - -0.7447 - 1.578 0.37 - 206.3 1 2 0 -0.0007 9 0 0 0 2.00E+08 8.76E+07 - - - 3.0933 0.9995 221125_WJC_METTL3_EV_vs_WT_F04.08386.08386.2 0.0112 16-Oct R.TEDQTLITK[136.11].R "sp|Q12996|CSTF3_HUMAN,tr|E9PLP8|E9PLP8_HUMAN" 2 1055.559 1.05 43516 8386 2 1055.557594 528.7868 Cleavage stimulation factor subunit 3 OS=Homo sapiens OX=9606 GN=CSTF3 PE=1 SV=1 4.37 1966.8 - 1.61E+06 - - - -1.3367 - 1.955 0.323 - 430.2 1 2 0 -0.0014 9 0 0 0 4.60E+07 4.37E+07 - - - 3.3657 0.9997 221125_WJC_METTL3_EV_vs_WT_F04.08388.08388.2 0.000818 18-Sep R.QQVVLENAAK[136.11].K sp|Q01780|EXOSX_HUMAN 1 1106.6175 1.29 43518 8388 2 1106.616563 554.316 Exosome component 10 OS=Homo sapiens OX=9606 GN=EXOSC10 PE=1 SV=2 6 1967.1 - 480937 - - - -0.8675 - 1.877 0.385 - 344.8 1 2 0 -0.001 10 0 0 0 5.21E+07 4.04E+07 - - - 3.6419 0.9998 221125_WJC_METTL3_EV_vs_WT_F04.08389.08389.2 0.00081 22-Oct R.GLANPEPAPEPK.V "sp|O15027|SC16A_HUMAN,tr|Q8N9G1|Q8N9G1_HUMAN,tr|A0A3F2YNX0|A0A3F2YNX0_HUMAN,tr|A0A3F2YNZ0|A0A3F2YNZ0_HUMAN,tr|X6RGP5|X6RGP5_HUMAN,tr|F1T0I1|F1T0I1_HUMAN,tr|A0A0C4DH09|A0A0C4DH09_HUMAN" 7 1218.6245 0.84 43519 8389 2 1218.624194 610.3195 Protein transport protein Sec16A OS=Homo sapiens OX=9606 GN=SEC16A PE=1 SV=4 4.53 1967.2 - 316139 - - - -0.2117 - 1.951 0.491 - 311.1 1 2 0 -0.0003 12 0 0 0 9.91E+06 1.18E+07 - - - 4.426 0.9383 221125_WJC_METTL3_EV_vs_WT_F04.08391.08391.2 0.0508 26-May R.GNLGAGNGNLQGPR.H "sp|P43243|MATR3_HUMAN,tr|D6RE02|D6RE02_HUMAN,tr|B3KM87|B3KM87_HUMAN,tr|A8MXP9|A8MXP9_HUMAN,tr|D6RAY2|D6RAY2_HUMAN,tr|D6R991|D6R991_HUMAN,tr|A0A0R4J2E8|A0A0R4J2E8_HUMAN,tr|D6RAM9|D6RAM9_HUMAN,tr|D6RIA2|D6RIA2_HUMAN,tr|H0Y8T4|H0Y8T4_HUMAN,tr|D6REM6|D6REM6_HUMAN,tr|D6RBI2|D6RBI2_HUMAN" 12 1323.6644 999 43521 8391 2 1323.667563 662.8395 Matrin-3 OS=Homo sapiens OX=9606 GN=MATR3 PE=1 SV=2 9.75 1967.4 - 156713 - - - 2.4198 - 1.255 0.088 - 48.9 2 2 0 0.0032 14 0 0 0 2.95E+06 0.00E+00 - - - 0.1255 0.9966 221125_WJC_METTL3_EV_vs_WT_F04.08398.08398.2 0.00012 16-Sep K.TAVC[160.03]DIPPR[166.11].G "sp|P04350|TBB4A_HUMAN,sp|Q9BVA1|TBB2B_HUMAN,sp|A6NNZ2|TBB8B_HUMAN,sp|P07437|TBB5_HUMAN,sp|Q13885|TBB2A_HUMAN,sp|P68371|TBB4B_HUMAN,sp|Q3ZCM7|TBB8_HUMAN,tr|Q5ST81|Q5ST81_HUMAN,tr|Q5JP53|Q5JP53_HUMAN,tr|A0A075B736|A0A075B736_HUMAN,tr|Q5SQY0|Q5SQY0_HUMAN" 11 1037.5203 1.07 43526 8398 2 1037.525156 519.7674 Tubulin beta-4A chain OS=Homo sapiens OX=9606 GN=TUBB4A PE=1 SV=2 5.5 1968.1 - 959005 - - - 4.6467 - 1.774 0.44 - 363.1 1 2 0 0.0048 9 0 0 0 2.60E+07 2.42E+07 - - - 3.9477 0.9959 221125_WJC_METTL3_EV_vs_WT_F04.08402.08402.2 0.414 16-Sep K.EQLAQAVAR[166.11].L "sp|Q00341|VIGLN_HUMAN,tr|A0A024R4E5|A0A024R4E5_HUMAN,tr|H7C0A4|H7C0A4_HUMAN,tr|H0Y394|H0Y394_HUMAN" 4 994.5435 1.22 43528 8402 2 994.543561 498.279 Vigilin OS=Homo sapiens OX=9606 GN=HDLBP PE=1 SV=2 6.1 1968.6 - 1.47E+06 - - - 0.0483 - 1.927 0.06 - 378.9 2 2 0 0 9 0 0 0 6.03E+07 4.94E+07 - - - 1.2474 0.9952 221125_WJC_METTL3_EV_vs_WT_F04.08404.08404.2 1.32 16-Aug K.EQLAQAVAR.L "sp|Q00341|VIGLN_HUMAN,tr|A0A024R4E5|A0A024R4E5_HUMAN,tr|H7C0A4|H7C0A4_HUMAN,tr|H0Y394|H0Y394_HUMAN" 4 984.5352 1.22 43530 8404 2 984.536027 493.2749 Vigilin OS=Homo sapiens OX=9606 GN=HDLBP PE=1 SV=2 6.1 1968.8 - 1.63E+06 - - - 0.7963 - 1.704 0.093 - 277.3 1 2 0 0.0008 9 0 0 0 6.03E+07 4.94E+07 - - - 1.2696 0.974 221125_WJC_METTL3_EV_vs_WT_F04.08405.08405.2 6.39 14-Jun K.MSAEDIEK[136.11].V "sp|Q9ULC4|MCTS1_HUMAN,tr|A0A3B3IRV3|A0A3B3IRV3_HUMAN" 2 929.4255 0.38 43531 8405 2 929.426092 465.7201 Malignant T-cell-amplified sequence 1 OS=Homo sapiens OX=9606 GN=MCTS1 PE=1 SV=1 4.14 1968.9 - 1.20E+06 - - - 0.5853 - 1.25 0.089 - 101 5 2 0 0.0005 8 0 0 0 1.33E+07 3.51E+07 - - - 0.0589 0.9991 221125_WJC_METTL3_EV_vs_WT_F04.08407.08407.2 0.00164 16-Aug K.YMEENDQLK[136.11].K "sp|P51572|BAP31_HUMAN,tr|A0A2R8Y5M6|A0A2R8Y5M6_HUMAN,tr|C9J0M4|C9J0M4_HUMAN,tr|C9JQ75|C9JQ75_HUMAN,tr|C9JSP1|C9JSP1_HUMAN,tr|C9JMD7|C9JMD7_HUMAN" 6 1176.5212 0.64 43533 8407 2 1176.519224 589.2679 B-cell receptor-associated protein 31 OS=Homo sapiens OX=9606 GN=BCAP31 PE=1 SV=3 4.14 1969.1 - 372130 - - - -1.7127 - 1.222 0.457 - 149 1 2 0 -0.002 9 0 0 0 1.10E+07 1.72E+07 - - - 2.9958 0.9963 221125_WJC_METTL3_EV_vs_WT_F04.08411.08411.2 2.16 12-Aug R.HLQLAVR[166.11].N sp|Q8IUE6|H2A2B_HUMAN 1 845.5111 1.05 43535 8411 2 845.511645 423.7628 Histone H2A type 2-B OS=Homo sapiens OX=9606 GN=H2AC21 PE=1 SV=3 9.76 1969.6 - 3.06E+06 - - - 0.6552 - 1.569 0.129 - 266.7 1 2 0 0.0006 7 0 0 0 1.07E+08 1.02E+08 - - - 1.4209 0.9997 221125_WJC_METTL3_EV_vs_WT_F04.08412.08412.2 0.000947 20-Oct K.TLESQAVETEK.V "sp|Q9NVX2|NLE1_HUMAN,tr|A0A0A0MRH0|A0A0A0MRH0_HUMAN,tr|K7ERN7|K7ERN7_HUMAN" 3 1233.6089 0.37 43536 8412 2 1233.611084 617.8117 Notchless protein homolog 1 OS=Homo sapiens OX=9606 GN=NLE1 PE=1 SV=4 4.25 1969.7 - 542514 - - - 1.8012 - 1.781 0.504 - 183.5 1 2 0 0.0022 11 0 0 0 1.03E+07 2.79E+07 - - - 4.3242 0.998 221125_WJC_METTL3_EV_vs_WT_F04.08413.08413.2 7.39 12-Sep R.HLQLAVR.N sp|Q8IUE6|H2A2B_HUMAN 1 835.5028 1.04 43537 8413 2 835.502817 418.7587 Histone H2A type 2-B OS=Homo sapiens OX=9606 GN=H2AC21 PE=1 SV=3 9.76 1969.8 - 2.95E+06 - - - -0.0048 - 1.527 0.192 - 324.7 1 2 0 0 7 0 0 0 1.04E+08 9.99E+07 - - - 1.8004 0.997 221125_WJC_METTL3_EV_vs_WT_F04.08414.08414.2 2.8 16-Jul R.QLETLGQEK[136.11].L "sp|P05787|K2C8_HUMAN,tr|F8VUG2|F8VUG2_HUMAN,tr|F8VP67|F8VP67_HUMAN,tr|Q8IWY7|Q8IWY7_HUMAN,tr|F8W1U3|F8W1U3_HUMAN" 5 1052.5593 16.9 43538 8414 2 1052.558727 527.2869 "Keratin, type II cytoskeletal 8 OS=Homo sapiens OX=9606 GN=KRT8 PE=1 SV=7" 4.53 1969.9 - 1.54E+06 - - - -0.5814 - 1.43 0.196 - 168.8 1 2 0 -0.0006 9 0 0 0 1.13E+09 6.66E+07 - - - 1.5232 0.9995 221125_WJC_METTL3_EV_vs_WT_F04.08419.08419.2 3.86E-05 20-Nov R.VATSSLDQTVK.L "sp|Q9BV38|WDR18_HUMAN,tr|U3KQC1|U3KQC1_HUMAN,tr|A0A0A0MQU0|A0A0A0MQU0_HUMAN,tr|K7EML4|K7EML4_HUMAN,tr|K7EIR0|K7EIR0_HUMAN" 5 1147.6085 1.1 43541 8419 2 1147.605173 574.8115 WD repeat-containing protein 18 OS=Homo sapiens OX=9606 GN=WDR18 PE=1 SV=2 5.81 1970.5 - 1.05E+06 - - - -2.8712 - 2.329 0.46 - 439.7 1 2 0 -0.0033 11 0 0 0 1.77E+08 1.62E+08 - - - 4.7246 0.9964 221125_WJC_METTL3_EV_vs_WT_F04.08420.08420.2 0.188 12-Jun R.SQTGWPR[166.11].G sp|O43809|CPSF5_HUMAN 1 840.4118 1.93 43542 8420 2 840.41098 421.2132 Cleavage and polyadenylation specificity factor subunit 5 OS=Homo sapiens OX=9606 GN=NUDT21 PE=1 SV=1 9.47 1970.6 - 884982 - - - -0.9412 - 1.276 0.222 - 165 1 2 0 -0.0008 7 0 0 0 6.03E+07 3.12E+07 - - - 1.4527 0.9964 221125_WJC_METTL3_EV_vs_WT_F04.08421.08421.2 0.196 16-Jul K.YMEENDQLK.K "sp|P51572|BAP31_HUMAN,tr|A0A2R8Y5M6|A0A2R8Y5M6_HUMAN,tr|C9J0M4|C9J0M4_HUMAN,tr|C9JQ75|C9JQ75_HUMAN,tr|C9JSP1|C9JSP1_HUMAN,tr|C9JMD7|C9JMD7_HUMAN" 6 1168.507 0.64 43543 8421 2 1168.506756 585.2608 B-cell receptor-associated protein 31 OS=Homo sapiens OX=9606 GN=BCAP31 PE=1 SV=3 4.14 1970.7 - 425503 - - - -0.2422 - 1.146 0.258 - 118 1 2 0 -0.0003 9 0 0 0 1.09E+07 1.69E+07 - - - 1.3408 0.9999 221125_WJC_METTL3_EV_vs_WT_F04.08424.08424.2 0.000207 16-Sep K.AQYEEIANR.S "sp|P13647|K2C5_HUMAN,tr|H0YI76|H0YI76_HUMAN,tr|H0YIN9|H0YIN9_HUMAN" 3 1092.52 17.07 43544 8424 2 1092.520309 547.2673 "Keratin, type II cytoskeletal 5 OS=Homo sapiens OX=9606 GN=KRT5 PE=1 SV=3" 4.53 1971.2 - 4.55E+06 - - - 0.2947 - 1.906 0.527 - 467.3 1 2 0 0.0003 9 0 0 0 6.19E+08 3.63E+07 - - - 4.7994 0.9993 221125_WJC_METTL3_EV_vs_WT_F04.08425.08425.2 0.00123 16-Sep K.AEFEEQNVR.K "sp|Q9UFW8|CGBP1_HUMAN,tr|C9JUJ0|C9JUJ0_HUMAN" 2 1120.5149 0.75 43545 8425 2 1120.516995 561.2647 CGG triplet repeat-binding protein 1 OS=Homo sapiens OX=9606 GN=CGGBP1 PE=1 SV=2 4.25 1971.3 - 413935 - - - 1.8679 - 1.814 0.375 - 417.9 1 2 0 0.0021 9 0 0 0 1.36E+07 1.81E+07 - - - 3.533 0.9509 221125_WJC_METTL3_EV_vs_WT_F04.08426.08426.2 0.0161 14-Aug R.R[166.11]EGAEIRN.K "sp|Q9UI32|GLSL_HUMAN,tr|A0A087X004|A0A087X004_HUMAN" 2 953.4918 - 43546 8426 2 953.492602 477.7532 "Glutaminase liver isoform, mitochondrial OS=Homo sapiens OX=9606 GN=GLS2 PE=1 SV=2" 6.14 1971.3 - 3.77E+06 - - - 0.8285 - 1.526 0.322 - 260.9 1 1 0 0.0008 8 0 0 0 - - - - - 2.6937 0.9996 221125_WJC_METTL3_EV_vs_WT_F04.08432.08432.2 0.00288 18-Nov R.QQVVLENAAK.K sp|Q01780|EXOSX_HUMAN 1 1098.6033 1.18 43549 8432 2 1098.603158 550.3089 Exosome component 10 OS=Homo sapiens OX=9606 GN=EXOSC10 PE=1 SV=2 6 1972.1 - 2.56E+06 - - - -0.1502 - 1.896 0.332 - 579.9 1 2 0 -0.0002 10 0 0 0 4.74E+07 4.03E+07 - - - 3.2788 1 221125_WJC_METTL3_EV_vs_WT_F04.08435.08435.3 0.000302 14/40 R.TAATLATHELR[166.11].A sp|Q8N1G4|LRC47_HUMAN 1 1192.644 1 43551 8435 3 1192.643385 398.5553 Leucine-rich repeat-containing protein 47 OS=Homo sapiens OX=9606 GN=LRRC47 PE=1 SV=1 6.41 1972.4 - 245646 - - - -0.4788 - 2.629 0.451 - 282.8 1 2 0 -0.0006 11 0 0 0 5.68E+07 5.71E+07 - - - 6.314 0.994 221125_WJC_METTL3_EV_vs_WT_F04.08439.08439.2 0.00704 16-Aug K.SAAMTLNER[166.11].F "sp|Q9NYF8|BCLF1_HUMAN,tr|E9PKI6|E9PKI6_HUMAN,tr|A0A1W2PQ43|A0A1W2PQ43_HUMAN,tr|E9PK91|E9PK91_HUMAN,tr|E9PK09|E9PK09_HUMAN,tr|E9PQN2|E9PQN2_HUMAN" 6 1001.484 0.42 43553 8439 2 1001.47915 501.7493 Bcl-2-associated transcription factor 1 OS=Homo sapiens OX=9606 GN=BCLAF1 PE=1 SV=2 5.72 1972.9 - 219245 - - - -4.7929 - 1.692 0.379 - 172.4 1 2 0 -0.0048 9 0 0 0 2.84E+07 6.70E+07 - - - 3.3603 0.8862 221125_WJC_METTL3_EV_vs_WT_F04.08441.08441.2 1.27 18-Jun R.SSPLLGGNGK.A sp|Q9C075|K1C23_HUMAN 1 928.4978 26.89 43555 8441 2 928.495374 465.2562 "Keratin, type I cytoskeletal 23 OS=Homo sapiens OX=9606 GN=KRT23 PE=1 SV=2" 8.47 1973 - 1.36E+06 - - - -2.6074 - 1.055 0.135 - 68.3 9 2 0 -0.0024 10 0 0 0 4.36E+07 1.62E+06 - - - -0.2395 0.9997 221125_WJC_METTL3_EV_vs_WT_F04.08443.08443.2 0.363 16-Aug K.ADIDVSGPK.V "sp|Q09666|AHNK_HUMAN,sp|Q09666|AHNK_HUMAN,sp|Q09666|AHNK_HUMAN,sp|Q09666|AHNK_HUMAN" 4 900.4553 2.24 43557 8443 2 900.45434 451.2349 Neuroblast differentiation-associated protein AHNAK OS=Homo sapiens OX=9606 GN=AHNAK PE=1 SV=2 4.21 1973.3 - 343902 - - - -1.0239 - 1.889 0.391 - 173.1 1 2 0 -0.0009 9 0 0 0 7.94E+06 3.54E+06 - - - 3.7688 0.9982 221125_WJC_METTL3_EV_vs_WT_F04.08446.08446.2 0.000321 16-Sep R.YESLTDPSK.L "sp|Q58FF8|H90B2_HUMAN,sp|P08238|HS90B_HUMAN,sp|Q58FF6|H90B4_HUMAN,sp|Q58FF7|H90B3_HUMAN,sp|P07900|HS90A_HUMAN,sp|Q14568|HS902_HUMAN,tr|G3V2J8|G3V2J8_HUMAN" 7 1038.487 0.99 43558 8446 2 1038.4836 520.2508 Putative heat shock protein HSP 90-beta 2 OS=Homo sapiens OX=9606 GN=HSP90AB2P PE=1 SV=2 4.37 1973.6 - 884338 - - - -3.2316 - 1.59 0.416 - 239.7 1 2 0 -0.0034 9 0 0 0 4.59E+08 4.61E+08 - - - 3.4541 0.9996 221125_WJC_METTL3_EV_vs_WT_F04.08448.08448.2 0.00327 18-Oct K.GEELSEANVR.L "sp|Q14203|DCTN1_HUMAN,tr|A0A804CDA6|A0A804CDA6_HUMAN,tr|E7EX90|E7EX90_HUMAN,tr|A0A7P0Z4C3|A0A7P0Z4C3_HUMAN" 4 1102.5255 2.09 43560 8448 2 1102.523269 552.27 Dynactin subunit 1 OS=Homo sapiens OX=9606 GN=DCTN1 PE=1 SV=3 4.25 1973.8 - 2.43E+06 - - - -1.9936 - 2.043 0.424 - 494.3 1 2 0 -0.0022 10 0 0 0 4.07E+07 1.94E+07 - - - 4.1661 0.9998 221125_WJC_METTL3_EV_vs_WT_F04.08449.08449.3 0.235 15/40 R.TAATLATHELR.A sp|Q8N1G4|LRC47_HUMAN 1 1182.6357 0.83 43561 8449 3 1182.63386 395.2192 Leucine-rich repeat-containing protein 47 OS=Homo sapiens OX=9606 GN=LRRC47 PE=1 SV=1 6.41 1974 - 476259 - - - -1.544 - 3.029 0.265 - 388.1 1 2 0 -0.0018 11 0 0 0 4.70E+07 5.67E+07 - - - 4.6423 0.9988 221125_WJC_METTL3_EV_vs_WT_F04.08454.08454.2 0.00182 20-Oct R.TAATLATHELR[166.11].A sp|Q8N1G4|LRC47_HUMAN 1 1192.644 0.67 43564 8454 2 1192.639304 597.3293 Leucine-rich repeat-containing protein 47 OS=Homo sapiens OX=9606 GN=LRRC47 PE=1 SV=1 6.41 1974.6 - 430725 - - - -3.9006 - 2.351 0.448 - 356.8 1 2 0 -0.0047 11 0 0 0 1.17E+07 1.76E+07 - - - 4.661 0.9939 221125_WJC_METTL3_EV_vs_WT_F04.08459.08459.2 0.468 14-May K.RPLESYVK.K "sp|Q10472|GALT1_HUMAN,tr|K7EJV8|K7EJV8_HUMAN" 2 990.5498 1.59 43566 8459 2 990.548723 496.2822 Polypeptide N-acetylgalactosaminyltransferase 1 OS=Homo sapiens OX=9606 GN=GALNT1 PE=1 SV=1 8.59 1975.2 - 802957 - - - -1.1186 - 1.32 0.198 - 115.1 3 2 0 -0.0011 8 0 0 0 2.67E+07 1.68E+07 - - - 1.1273 0.8521 221125_WJC_METTL3_EV_vs_WT_F04.08460.08460.2 0.351 14-Jun R.YTDPSSLR[166.11].K "sp|P08151|GLI1_HUMAN,sp|Q8NEA6|GLIS3_HUMAN,sp|P10071|GLI3_HUMAN,sp|Q8NBF1|GLIS1_HUMAN,sp|P10070|GLI2_HUMAN,sp|Q9BZE0|GLIS2_HUMAN,tr|A0A0D9SEX9|A0A0D9SEX9_HUMAN,tr|A0A2R8YGX0|A0A2R8YGX0_HUMAN,tr|A0A7I2V4X9|A0A7I2V4X9_HUMAN,tr|A0A7I2PJA1|A0A7I2PJA1_HUMAN" 10 947.4588 21.63 43567 8460 2 947.462576 474.7367 Zinc finger protein GLI1 OS=Homo sapiens OX=9606 GN=GLI1 PE=1 SV=1 5.84 1975.4 - 496573 - - - 4.0055 - 0.927 0.193 - 93.9 1 2 0 0.0038 8 0 0 0 2.05E+08 9.48E+06 - - - 0.2367 0.9937 221125_WJC_METTL3_EV_vs_WT_F04.08461.08461.2 0.36 12-Jun K.EDPQLPR.K "sp|Q8WU79|SMAP2_HUMAN,tr|A0A087WV97|A0A087WV97_HUMAN,tr|X6RCC3|X6RCC3_HUMAN" 3 853.4294 1.88 43568 8461 2 853.427547 427.722 Stromal membrane-associated protein 2 OS=Homo sapiens OX=9606 GN=SMAP2 PE=1 SV=1 4.37 1975.4 - 3.84E+06 - - - -2.149 - 1.311 0.227 - 143.4 1 2 0 -0.0018 7 0 0 0 1.25E+08 6.64E+07 - - - 1.5751 0.9947 221125_WJC_METTL3_EV_vs_WT_F04.08462.08462.2 0.079 12-Jun K.EDPQLPR[166.11].K "sp|Q8WU79|SMAP2_HUMAN,tr|A0A087WV97|A0A087WV97_HUMAN,tr|X6RCC3|X6RCC3_HUMAN" 3 863.4377 1.88 43569 8462 2 863.435951 432.7261 Stromal membrane-associated protein 2 OS=Homo sapiens OX=9606 GN=SMAP2 PE=1 SV=1 4.37 1975.5 - 2.09E+06 - - - -1.9689 - 1.246 0.253 - 212.7 1 2 0 -0.0017 7 0 0 0 1.25E+08 6.64E+07 - - - 1.606 0.9946 221125_WJC_METTL3_EV_vs_WT_F04.08463.08463.2 0.00727 14-Aug R.EAESLIAK[136.11].K "sp|P78371|TCPB_HUMAN,tr|F8VQ14|F8VQ14_HUMAN,tr|F5GWF6|F5GWF6_HUMAN" 3 867.4793 0.51 43570 8463 2 867.475704 434.7469 T-complex protein 1 subunit beta OS=Homo sapiens OX=9606 GN=CCT2 PE=1 SV=4 4.53 1975.5 - 1.99E+06 - - - -4.143 - 1.613 0.339 - 357.6 1 2 0 -0.0036 8 0 0 0 2.18E+07 4.29E+07 - - - 2.9856 0.9996 221125_WJC_METTL3_EV_vs_WT_F04.08467.08467.2 0.00896 14-Oct K.VGEVIVTK[136.11].D "sp|P10809|CH60_HUMAN,tr|A0A7I2V2X6|A0A7I2V2X6_HUMAN,tr|A0A7I2YQK6|A0A7I2YQK6_HUMAN,tr|A0A7I2V599|A0A7I2V599_HUMAN" 4 851.5208 2.24 43572 8467 2 851.519728 426.7677 "60 kDa heat shock protein, mitochondrial OS=Homo sapiens OX=9606 GN=HSPD1 PE=1 SV=2" 5.97 1976 - 4.70E+06 - - - -1.2225 - 2.152 0.297 - 272.5 1 2 0 -0.001 8 0 0 0 1.87E+08 8.33E+07 - - - 3.5457 0.9918 221125_WJC_METTL3_EV_vs_WT_F04.08470.08470.2 1.79E-05 13/20 R.TAATLATHELR.A sp|Q8N1G4|LRC47_HUMAN 1 1182.6357 0.65 43575 8470 2 1182.627819 592.3251 Leucine-rich repeat-containing protein 47 OS=Homo sapiens OX=9606 GN=LRRC47 PE=1 SV=1 6.41 1976.4 - 375877 - - - -6.6521 - 2.584 0.413 - 813.5 1 2 0 -0.0079 11 0 0 0 1.14E+07 1.76E+07 - - - 4.6571 0.9988 221125_WJC_METTL3_EV_vs_WT_F04.08473.08473.2 0.0489 14-Aug R.ETIQNLSR.L "sp|Q15643|TRIPB_HUMAN,tr|H0YJ97|H0YJ97_HUMAN" 2 959.5036 1.46 43577 8473 2 959.502746 480.7591 Thyroid receptor-interacting protein 11 OS=Homo sapiens OX=9606 GN=TRIP11 PE=1 SV=3 6.1 1976.7 - 1.40E+07 - - - -0.8994 - 1.63 0.247 - 249.6 1 2 0 -0.0009 8 0 0 0 2.82E+08 1.93E+08 - - - 2.3386 0.9993 221125_WJC_METTL3_EV_vs_WT_F04.08476.08476.2 0.142 14-Sep K.VGEVIVTK.D "sp|P10809|CH60_HUMAN,tr|A0A7I2V2X6|A0A7I2V2X6_HUMAN,tr|A0A7I2YQK6|A0A7I2YQK6_HUMAN,tr|A0A7I2V599|A0A7I2V599_HUMAN" 4 843.5066 2.24 43579 8476 2 843.505007 422.7606 "60 kDa heat shock protein, mitochondrial OS=Homo sapiens OX=9606 GN=HSPD1 PE=1 SV=2" 5.97 1976.9 - 5.77E+06 - - - -1.8518 - 2.042 0.299 - 264.2 1 2 0 -0.0016 8 0 0 0 1.88E+08 8.39E+07 - - - 3.4021 0.9998 221125_WJC_METTL3_EV_vs_WT_F04.08477.08477.2 0.0109 18-Nov K.LQAEISQAAR.K sp|O43395|PRPF3_HUMAN 1 1085.5829 2.24 43580 8477 2 1085.581793 543.7987 U4\U6 small nuclear ribonucleoprotein Prp3 OS=Homo sapiens OX=9606 GN=PRPF3 PE=1 SV=2 6 1977 - 3.93E+06 - - - -1.04 - 2.15 0.398 - 415.7 1 2 0 -0.0011 10 0 0 0 5.46E+08 2.44E+08 - - - 4.1169 0.9868 221125_WJC_METTL3_EV_vs_WT_F04.08478.08478.2 0.545 14-Aug R.DIQSLPQK[136.11].A sp|Q9H223|EHD4_HUMAN 1 935.5167 1.44 43581 8478 2 935.515694 468.7656 EH domain-containing protein 4 OS=Homo sapiens OX=9606 GN=EHD4 PE=1 SV=1 5.84 1977.1 - 667322 - - - -1.1245 - 1.157 0.15 - 209 1 2 0 -0.0011 8 0 0 0 1.02E+08 7.08E+07 - - - 0.5884 0.8893 221125_WJC_METTL3_EV_vs_WT_F04.08481.08481.2 2.73 12-Jul K.EGININR[166.11].G "sp|O95239|KIF4A_HUMAN,sp|Q2VIQ3|KIF4B_HUMAN" 2 824.438 1.97 43584 8481 2 824.43503 413.2263 Chromosome-associated kinesin KIF4A OS=Homo sapiens OX=9606 GN=KIF4A PE=1 SV=3 6.1 1977.5 - 366117 - - - -3.5855 - 1.292 0.052 - 148 1 2 0 -0.003 7 0 0 0 1.13E+07 5.73E+06 - - - 0.2359 0.9148 221125_WJC_METTL3_EV_vs_WT_F04.08485.08485.2 0.471 12-Jun R.ANITAIR[166.11].R "sp|P49368|TCPG_HUMAN,sp|Q9NR96|TLR9_HUMAN,tr|H0Y858|H0Y858_HUMAN,tr|B4DUR8|B4DUR8_HUMAN" 4 767.4529 0.02 43586 8485 2 767.451093 384.7337 T-complex protein 1 subunit gamma OS=Homo sapiens OX=9606 GN=CCT3 PE=1 SV=4 9.79 1978 - 686797 - - - -2.3637 - 1.288 0.001 - 189.3 1 2 0 -0.0018 7 0 0 0 2.60E+05 1.28E+07 - - - -0.1503 0.9986 221125_WJC_METTL3_EV_vs_WT_F04.08487.08487.2 0.632 14-Aug R.ITQSEFDR.Q "sp|Q9Y371|SHLB1_HUMAN,tr|A0A087WW40|A0A087WW40_HUMAN" 2 994.472 1.2 43588 8487 2 994.469804 498.2433 Endophilin-B1 OS=Homo sapiens OX=9606 GN=SH3GLB1 PE=1 SV=1 4.37 1978.2 - 1.58E+06 - - - -2.1821 - 1.905 0.258 - 259.3 1 2 0 -0.0022 8 0 0 0 6.69E+07 5.60E+07 - - - 2.8896 0.9136 221125_WJC_METTL3_EV_vs_WT_F04.08490.08490.2 1.95 16-Apr K.GDEC[160.03]LGSGK.L sp|O75648|MTU1_HUMAN 1 921.3862 1.77 43591 8490 2 921.387399 461.7004 Mitochondrial tRNA-specific 2-thiouridylase 1 OS=Homo sapiens OX=9606 GN=TRMU PE=1 SV=2 4.37 1978.5 - 627951 - - - 1.3056 - 0.759 0.166 - 63.7 1 2 0 0.0012 9 0 0 0 5.36E+06 3.03E+06 - - - -0.5311 0.8158 221125_WJC_METTL3_EV_vs_WT_F04.08498.08498.2 0.000122 20-Nov N.IAMTSGTVQPK.Q sp|Q14677|EPN4_HUMAN 1 1131.5958 1.67 43597 8498 2 1131.590638 566.8052 Clathrin interactor 1 OS=Homo sapiens OX=9606 GN=CLINT1 PE=1 SV=1 8.75 1979.5 - 1.07E+06 - - - -4.5573 - 2.301 0.327 - 354.8 1 1 0 -0.0052 11 0 0 0 2.58E+07 1.55E+07 - - - 3.709 0.9993 221125_WJC_METTL3_EV_vs_WT_F04.08502.08502.3 0.00988 Sep-40 K.ILTHVAEMQGK.S sp|Q9UH99|SUN2_HUMAN 1 1225.6489 0.81 43601 8502 3 1225.648401 409.5569 SUN domain-containing protein 2 OS=Homo sapiens OX=9606 GN=SUN2 PE=1 SV=3 6.75 1980 - 491044 - - - -0.4014 - 1.694 0.318 - 72.8 1 2 0 -0.0005 11 0 0 0 7.79E+06 9.56E+06 - - - 3.5826 0.9939 221125_WJC_METTL3_EV_vs_WT_F04.08503.08503.2 0.259 12-Jun R.ADAVWNK[136.11].L "sp|P42704|LPPRC_HUMAN,tr|A0A804HI14|A0A804HI14_HUMAN,tr|A0A804HL40|A0A804HL40_HUMAN,tr|A0A804HKJ0|A0A804HKJ0_HUMAN,tr|A0A804HKR3|A0A804HKR3_HUMAN,tr|A0A804HIN4|A0A804HIN4_HUMAN,tr|A0A804HJG8|A0A804HJG8_HUMAN,tr|A0A804HLG8|A0A804HLG8_HUMAN,tr|A0A804HI40|A0A804HI40_HUMAN,tr|A0A804HJZ1|A0A804HJZ1_HUMAN,tr|A0A804HIQ7|A0A804HIQ7_HUMAN,tr|A0A804HK30|A0A804HK30_HUMAN,tr|A0A804HKI2|A0A804HKI2_HUMAN,tr|A0A804HJI0|A0A804HJI0_HUMAN,tr|A0A804HIG4|A0A804HIG4_HUMAN" 15 810.4116 1.01 43602 8503 2 810.409409 406.2131 "Leucine-rich PPR motif-containing protein, mitochondrial OS=Homo sapiens OX=9606 GN=LRPPRC PE=1 SV=3" 5.88 1980.1 - 270074 - - - -2.6456 - 1.204 0.305 - 133.8 1 2 0 -0.0021 7 0 0 0 8.32E+06 8.23E+06 - - - 1.8813 0.9953 221125_WJC_METTL3_EV_vs_WT_F04.08506.08506.2 0.102 18-Sep K.LQAEISQAAR[166.11].K sp|O43395|PRPF3_HUMAN 1 1095.5912 2.24 43603 8506 2 1095.587111 548.8029 U4\U6 small nuclear ribonucleoprotein Prp3 OS=Homo sapiens OX=9606 GN=PRPF3 PE=1 SV=2 6 1980.5 - 1.28E+07 - - - -3.7249 - 1.972 0.254 - 275.6 1 2 0 -0.0041 10 0 0 0 5.46E+08 2.44E+08 - - - 2.8112 0.8924 221125_WJC_METTL3_EV_vs_WT_F04.08527.08527.2 0.813 14-Aug R.R[166.11]AVLETIR[166.11].T sp|Q5JTH9|RRP12_HUMAN 1 976.5933 0.84 43621 8527 2 976.589332 489.3039 RRP12-like protein OS=Homo sapiens OX=9606 GN=RRP12 PE=1 SV=2 9.6 1982.7 - 541026 - - - -4.016 - 1.213 0.132 - 85.3 2 2 0 -0.0039 8 0 0 0 3.49E+06 4.16E+06 - - - 0.4626 0.9687 221125_WJC_METTL3_EV_vs_WT_F04.08530.08530.2 0.223 18-Jul K.AVPVESPVQK[136.11].V sp|Q8TB61|S35B2_HUMAN 1 1060.6008 0.77 43622 8530 2 1060.597236 531.3077 Adenosine 3'-phospho 5'-phosphosulfate transporter 1 OS=Homo sapiens OX=9606 GN=SLC35B2 PE=1 SV=1 6.05 1983.1 - 793957 - - - -3.3698 - 1.291 0.174 - 118.5 1 2 0 -0.0036 10 0 0 0 1.87E+07 2.43E+07 - - - 1.038 0.9954 221125_WJC_METTL3_EV_vs_WT_F04.08541.08541.2 0.00439 18-Sep R.LVTANTIDQK[136.11].L "sp|Q9NRZ9|HELLS_HUMAN,tr|Q9NW36|Q9NW36_HUMAN,tr|A0A087WSW7|A0A087WSW7_HUMAN,tr|A0A0B4J1V9|A0A0B4J1V9_HUMAN,tr|F6XU50|F6XU50_HUMAN" 5 1109.6172 0.74 43631 8541 2 1109.612495 555.8159 Lymphoid-specific helicase OS=Homo sapiens OX=9606 GN=HELLS PE=1 SV=1 5.84 1984.3 - 925184 - - - -4.2303 - 1.871 0.327 - 206.5 1 2 0 -0.0047 10 0 0 0 3.50E+07 4.71E+07 - - - 3.2034 0.9989 221125_WJC_METTL3_EV_vs_WT_F04.08545.08545.2 0.000745 18-Sep R.LVTANTIDQK.L "sp|Q9NRZ9|HELLS_HUMAN,tr|Q9NW36|Q9NW36_HUMAN,tr|A0A087WSW7|A0A087WSW7_HUMAN,tr|A0A0B4J1V9|A0A0B4J1V9_HUMAN,tr|F6XU50|F6XU50_HUMAN" 5 1101.603 0.74 43635 8545 2 1101.59992 551.8088 Lymphoid-specific helicase OS=Homo sapiens OX=9606 GN=HELLS PE=1 SV=1 5.84 1984.8 - 524259 - - - -2.7859 - 1.785 0.402 - 201.8 1 2 0 -0.0031 10 0 0 0 3.50E+07 4.71E+07 - - - 3.6265 0.9997 221125_WJC_METTL3_EV_vs_WT_F04.08559.08559.2 4.65E-05 16-Oct R.QGANINEIR[166.11].Q sp|Q15365|PCBP1_HUMAN 1 1023.5337 0.97 43643 8559 2 1023.534019 512.7741 Poly(rC)-binding protein 1 OS=Homo sapiens OX=9606 GN=PCBP1 PE=1 SV=2 6 1986.5 - 4.46E+06 - - - 0.3341 - 2.188 0.308 - 608.5 1 2 0 0.0003 9 0 0 0 5.80E+08 5.99E+08 - - - 3.581 0.9989 221125_WJC_METTL3_EV_vs_WT_F04.08563.08563.2 0.00125 14-Aug K.QPTPVNIR.A "sp|Q9Y3Y2|CHTOP_HUMAN,tr|A0A087X1B7|A0A087X1B7_HUMAN,tr|X6R700|X6R700_HUMAN" 3 923.5189 3.06 43645 8563 2 923.517641 462.7667 Chromatin target of PRMT1 protein OS=Homo sapiens OX=9606 GN=CHTOP PE=1 SV=2 9.75 1987 - 2.10E+06 - - - -1.3254 - 1.305 0.377 - 321.2 1 2 0 -0.0012 8 0 0 0 1.29E+08 4.22E+07 - - - 2.628 0.9992 221125_WJC_METTL3_EV_vs_WT_F04.08565.08565.2 0.021 16-Sep K.NNLGTPLQK.L sp|Q9UKJ3|GPTC8_HUMAN 1 983.54 0.85 43646 8565 2 983.538184 492.7773 G patch domain-containing protein 8 OS=Homo sapiens OX=9606 GN=GPATCH8 PE=1 SV=2 8.75 1987.2 - 891500 - - - -1.8403 - 1.889 0.315 - 365.5 1 2 0 -0.0018 9 0 0 0 4.68E+07 5.51E+07 - - - 3.2071 0.9995 221125_WJC_METTL3_EV_vs_WT_F04.08569.08569.2 0.00541 16-Aug R.TYYYNTETK[136.11].Q "sp|O75400|PR40A_HUMAN,tr|F5H578|F5H578_HUMAN,tr|H0YG38|H0YG38_HUMAN,tr|A0A7N4I394|A0A7N4I394_HUMAN" 4 1189.5383 0.75 43648 8569 2 1189.5398 595.7764 Pre-mRNA-processing factor 40 homolog A OS=Homo sapiens OX=9606 GN=PRPF40A PE=1 SV=2 5.66 1987.7 - 468082 - - - 1.2862 - 1.376 0.483 - 152.8 1 2 0 0.0015 9 0 0 0 2.45E+07 3.29E+07 - - - 3.5314 0.9998 221125_WJC_METTL3_EV_vs_WT_F04.08571.08571.2 6.46E-06 20-Dec R.LVSSDPEINTK[136.11].K sp|Q9Y266|NUDC_HUMAN 1 1209.6332 1.81 43649 8571 2 1209.63116 605.8239 Nuclear migration protein nudC OS=Homo sapiens OX=9606 GN=NUDC PE=1 SV=1 4.37 1987.9 - 1.07E+06 - - - -1.7137 - 2.094 0.573 - 359 1 2 0 -0.0021 11 0 0 0 1.87E+09 1.04E+09 - - - 5.2719 0.9998 221125_WJC_METTL3_EV_vs_WT_F04.08573.08573.2 1.41E-05 20-Nov R.LVSSDPEINTK.K sp|Q9Y266|NUDC_HUMAN 1 1201.619 1.81 43650 8573 2 1201.61937 601.8168 Nuclear migration protein nudC OS=Homo sapiens OX=9606 GN=NUDC PE=1 SV=1 4.37 1988.1 - 2.40E+06 - - - 0.2805 - 2.047 0.479 - 304.3 1 2 0 0.0003 11 0 0 0 1.87E+09 1.04E+09 - - - 4.5168 0.9988 221125_WJC_METTL3_EV_vs_WT_F04.08575.08575.2 0.00108 22-Nov R.ITEAVATATEQR[166.11].E sp|Q13948|CASP_HUMAN 1 1298.6706 1.57 43651 8575 2 1298.665828 650.3426 Protein CASP OS=Homo sapiens OX=9606 GN=CUX1 PE=1 SV=2 4.53 1988.4 - 384063 - - - -3.6468 - 2.626 0.376 - 435.8 1 2 0 -0.0047 12 0 0 0 2.51E+07 1.60E+07 - - - 4.3569 0.9969 221125_WJC_METTL3_EV_vs_WT_F04.08583.08583.2 0.00833 16-Jul R.NVLLNNSEK[136.11].M sp|Q08J23|NSUN2_HUMAN 1 1037.5597 1.27 43655 8583 2 1037.561296 519.7871 RNA cytosine C(5)-methyltransferase NSUN2 OS=Homo sapiens OX=9606 GN=NSUN2 PE=1 SV=2 6 1989.2 - 7.27E+06 - - - 1.5633 - 1.188 0.319 - 113.3 1 2 0 0.0016 9 0 0 0 1.88E+08 1.48E+08 - - - 1.895 0.9996 221125_WJC_METTL3_EV_vs_WT_F04.08584.08584.2 0.000708 16-Aug R.FSATEVTNK.T "sp|Q8N163|CCAR2_HUMAN,tr|H0YB24|H0YB24_HUMAN,tr|G3V119|G3V119_HUMAN" 3 995.4924 0.66 43656 8584 2 995.494262 498.7535 Cell cycle and apoptosis regulator protein 2 OS=Homo sapiens OX=9606 GN=CCAR2 PE=1 SV=2 6 1989.3 - 2.61E+06 - - - 1.8955 - 1.783 0.462 - 145.2 1 2 0 0.0019 9 0 0 0 5.65E+07 8.54E+07 - - - 4.1258 0.9998 221125_WJC_METTL3_EV_vs_WT_F04.08589.08589.2 0.00545 14/22 R.ITEAVATATEQR.E sp|Q13948|CASP_HUMAN 1 1288.6623 1.57 43659 8589 2 1288.659944 645.3384 Protein CASP OS=Homo sapiens OX=9606 GN=CUX1 PE=1 SV=2 4.53 1989.9 - 1.02E+06 - - - -1.8236 - 2.767 0.464 - 694 1 2 0 -0.0024 12 0 0 0 2.51E+07 1.60E+07 - - - 5.1453 0.996 221125_WJC_METTL3_EV_vs_WT_F04.08593.08593.3 0.0035 Nov-36 R.LLEEEDSK[136.11]LK[136.11].G "sp|Q96CT7|CC124_HUMAN,tr|M0R2F5|M0R2F5_HUMAN" 2 1218.6678 0.7 43661 8593 3 1218.666703 407.2299 Coiled-coil domain-containing protein 124 OS=Homo sapiens OX=9606 GN=CCDC124 PE=1 SV=1 4.41 1990.5 - 1.48E+06 - - - -0.9281 - 2.034 0.25 - 111.1 1 2 1 -0.0011 10 0 0 0 3.56E+07 5.07E+07 - - - 3.4005 0.991 221125_WJC_METTL3_EV_vs_WT_F04.08596.08596.3 0.0179 Dec-36 R.LLEEEDSKLK.G "sp|Q96CT7|CC124_HUMAN,tr|M0R2F5|M0R2F5_HUMAN" 2 1202.6394 0.7 43663 8596 3 1202.632698 401.8871 Coiled-coil domain-containing protein 124 OS=Homo sapiens OX=9606 GN=CCDC124 PE=1 SV=1 4.41 1990.8 - 874182 - - - -5.601 - 2.216 0.408 - 141.6 1 2 1 -0.0067 10 0 0 0 3.56E+07 5.05E+07 - - - 5.4107 0.9353 221125_WJC_METTL3_EV_vs_WT_F04.08601.08601.2 0.181 14-Sep R.TSIETNIR[166.11].V "sp|P14859|PO2F1_HUMAN,sp|Q9UKI9|PO2F3_HUMAN,tr|H0YLC5|H0YLC5_HUMAN,tr|A0A0C4DG88|A0A0C4DG88_HUMAN,tr|A0A0A0MT46|A0A0A0MT46_HUMAN" 5 942.501 1.8 43666 8601 2 942.494232 472.2578 "POU domain, class 2, transcription factor 1 OS=Homo sapiens OX=9606 GN=POU2F1 PE=1 SV=2" 5.66 1991.4 - 1.97E+06 - - - -7.1597 - 1.829 0.228 - 298.2 1 2 0 -0.0067 8 0 0 0 8.99E+08 5.00E+08 - - - 2.5438 0.9498 221125_WJC_METTL3_EV_vs_WT_F04.08603.08603.2 0.0172 14-Sep L.QIDPTIQR.V "sp|O95678|K2C75_HUMAN,sp|P02538|K2C6A_HUMAN" 2 969.5243 999 43667 8603 2 969.526014 485.7694 "Keratin, type II cytoskeletal 75 OS=Homo sapiens OX=9606 GN=KRT75 PE=1 SV=2" 5.84 1991.7 - 1.05E+06 - - - 1.7225 - 1.738 0.328 - 424.8 1 1 0 0.0017 8 0 0 0 6.96E+07 0.00E+00 - - - 3.1301 0.9769 221125_WJC_METTL3_EV_vs_WT_F04.08612.08612.2 0.307 16-Jun R.SSPATADKR.Q "sp|Q8TF72|SHRM3_HUMAN,tr|A0A2R8Y5P9|A0A2R8Y5P9_HUMAN" 2 931.4723 11.78 43669 8612 2 931.468586 466.7434 Protein Shroom3 OS=Homo sapiens OX=9606 GN=SHROOM3 PE=1 SV=2 8.46 1992.9 - 3.13E+06 - - - -3.9969 - 1.25 0.26 - 135.9 1 2 0 -0.0037 9 0 0 0 2.19E+08 1.86E+07 - - - 1.6058 0.9991 221125_WJC_METTL3_EV_vs_WT_F04.08621.08621.2 0.00359 16-Aug K.GGYTSGTFR[166.11].T "sp|P25205|MCM3_HUMAN,tr|J3KQ69|J3KQ69_HUMAN,tr|A0A499FHX9|A0A499FHX9_HUMAN" 3 954.4435 0.29 43673 8621 2 954.441209 478.229 DNA replication licensing factor MCM3 OS=Homo sapiens OX=9606 GN=MCM3 PE=1 SV=3 8.75 1994 - 1.44E+06 - - - -2.3637 - 1.606 0.418 - 151.1 1 2 0 -0.0023 9 0 0 0 1.70E+07 5.79E+07 - - - 3.4982 0.9993 221125_WJC_METTL3_EV_vs_WT_F04.08623.08623.2 0.00461 16-Aug K.AQYEEIAQR.S "sp|P48668|K2C6C_HUMAN,sp|Q01546|K22O_HUMAN,sp|P19013|K2C4_HUMAN,sp|P04259|K2C6B_HUMAN,sp|P35908|K22E_HUMAN,sp|P02538|K2C6A_HUMAN" 6 1106.5356 5078.64 43674 8623 2 1106.532746 554.2751 "Keratin, type II cytoskeletal 6C OS=Homo sapiens OX=9606 GN=KRT6C PE=1 SV=3" 4.53 1994.2 - 1.95E+08 - - - -2.6127 - 1.815 0.434 - 337.2 1 2 0 -0.0029 9 0 0 0 1.73E+10 3.41E+06 - - - 3.9701 0.9934 221125_WJC_METTL3_EV_vs_WT_F04.08634.08634.2 1.87E-05 16-Oct K.DVDAAYVSK.V sp|Q7Z794|K2C1B_HUMAN 1 966.4658 335.37 43678 8634 2 966.459723 484.2402 "Keratin, type II cytoskeletal 1b OS=Homo sapiens OX=9606 GN=KRT77 PE=1 SV=3" 4.21 1995.6 - 1.70E+06 - - - -6.3148 - 1.933 0.499 - 243.3 1 2 0 -0.0061 9 0 0 0 2.89E+08 8.63E+05 - - - 4.6314 0.9993 221125_WJC_METTL3_EV_vs_WT_F04.08648.08648.3 0.00117 14/40 R.VLIAAHGNSLR.G "sp|P15259|PGAM2_HUMAN,sp|P18669|PGAM1_HUMAN" 2 1149.6618 0.94 43682 8648 3 1149.65668 384.2279 Phosphoglycerate mutase 2 OS=Homo sapiens OX=9606 GN=PGAM2 PE=1 SV=3 9.73 1997.6 - 1.64E+06 - - - -4.4891 - 2.484 0.409 - 268.4 1 2 0 -0.0052 11 0 0 0 5.98E+07 6.35E+07 - - - 5.6833 0.9997 221125_WJC_METTL3_EV_vs_WT_F04.08664.08664.2 1.80E-06 14-Sep K.DDEVQVVR.G "sp|Q9UNX3|RL26L_HUMAN,sp|P61254|RL26_HUMAN,tr|J3QQQ9|J3QQQ9_HUMAN,tr|E5RIT6|E5RIT6_HUMAN,tr|J3QQV1|J3QQV1_HUMAN,tr|J3QRC4|J3QRC4_HUMAN,tr|J3QRI7|J3QRI7_HUMAN" 7 958.472 0.92 43689 8664 2 958.469629 480.2433 60S ribosomal protein L26-like 1 OS=Homo sapiens OX=9606 GN=RPL26L1 PE=1 SV=1 4.03 1999.6 - 1.65E+06 - - - -2.4466 - 2.148 0.546 - 598.6 1 2 0 -0.0023 8 0 0 0 1.95E+08 2.13E+08 - - - 5.3788 0.9987 221125_WJC_METTL3_EV_vs_WT_F04.08671.08671.2 1.24E-05 14-Sep K.DDEVQVVR[166.11].G "sp|Q9UNX3|RL26L_HUMAN,sp|P61254|RL26_HUMAN,tr|J3QQQ9|J3QQQ9_HUMAN,tr|E5RIT6|E5RIT6_HUMAN,tr|J3QQV1|J3QQV1_HUMAN,tr|J3QRC4|J3QRC4_HUMAN,tr|J3QRI7|J3QRI7_HUMAN" 7 968.4802 0.91 43694 8671 2 968.476808 485.2474 60S ribosomal protein L26-like 1 OS=Homo sapiens OX=9606 GN=RPL26L1 PE=1 SV=1 4.03 2000.4 - 4.35E+06 - - - -3.5478 - 1.859 0.438 - 466.3 1 2 0 -0.0034 8 0 0 0 1.94E+08 2.13E+08 - - - 4.145 0.8153 221125_WJC_METTL3_EV_vs_WT_F04.08672.08672.3 0.0191 Dec-40 R.PASGPIR[166.11]PIVR[166.11].C "sp|P26373|RL13_HUMAN,tr|J3QSB4|J3QSB4_HUMAN" 2 1181.7148 1.12 43695 8672 3 1181.713238 394.9122 60S ribosomal protein L13 OS=Homo sapiens OX=9606 GN=RPL13 PE=1 SV=4 12 2000.5 - 2.28E+06 - - - -1.293 - 1.761 0.245 - 205 1 1 0 -0.0015 11 0 0 0 3.62E+08 3.23E+08 - - - 2.8787 0.9997 221125_WJC_METTL3_EV_vs_WT_F04.08675.08675.2 1.26E-05 20-Dec R.VEGSETPYVDR.T sp|Q96DF8|ESS2_HUMAN 1 1250.5779 2.04 43696 8675 2 1250.575035 626.2962 Splicing factor ESS-2 homolog OS=Homo sapiens OX=9606 GN=ESS2 PE=1 SV=1 4.14 2000.9 - 1.57E+06 - - - -2.2877 - 2.409 0.517 - 526.9 1 2 0 -0.0029 11 0 0 0 1.00E+08 4.92E+07 - - - 5.2371 0.9233 221125_WJC_METTL3_EV_vs_WT_F04.08677.08677.2 0.222 12-Aug K.WQQLQAK[136.11].R "sp|Q6P2Q9|PRP8_HUMAN,tr|I3L0J9|I3L0J9_HUMAN" 2 908.496 1.14 43698 8677 2 908.49216 455.2553 Pre-mRNA-processing-splicing factor 8 OS=Homo sapiens OX=9606 GN=PRPF8 PE=1 SV=2 8.75 2001.2 - 2.12E+06 - - - -4.1728 - 1.093 0.199 - 215.3 1 2 0 -0.0038 7 0 0 0 1.13E+08 9.93E+07 - - - 0.7914 0.997 221125_WJC_METTL3_EV_vs_WT_F04.08678.08678.2 0.583 12-Jun R.INIPPQR.G "sp|Q13283|G3BP1_HUMAN,tr|A0A7I2V5M7|A0A7I2V5M7_HUMAN,tr|A0A7P0P2U7|A0A7P0P2U7_HUMAN,tr|A0A7I2YQU8|A0A7I2YQU8_HUMAN,tr|A0A7I2V548|A0A7I2V548_HUMAN,tr|A0A7I2V565|A0A7I2V565_HUMAN,tr|A0A7I2YQN9|A0A7I2YQN9_HUMAN" 7 836.4868 -1 43699 8678 2 836.486427 419.2507 Ras GTPase-activating protein-binding protein 1 OS=Homo sapiens OX=9606 GN=G3BP1 PE=1 SV=1 9.75 2001.3 - 938335 - - - -0.4901 - 1.521 0.152 - 142.2 1 2 0 -0.0004 7 0 0 0 0.00E+00 0.00E+00 - - - 1.4923 0.9992 221125_WJC_METTL3_EV_vs_WT_F04.08681.08681.2 0.0346 14-Aug K.SSELQAIK[136.11].T "sp|Q9UKM9|RALY_HUMAN,tr|Q5QPM0|Q5QPM0_HUMAN,tr|Q5QPL9|Q5QPL9_HUMAN" 3 882.4902 1.3 43700 8681 2 882.489631 442.2524 RNA-binding protein Raly OS=Homo sapiens OX=9606 GN=RALY PE=1 SV=1 5.72 2001.7 - 951564 - - - -0.6414 - 1.731 0.267 - 230.6 1 2 0 -0.0006 8 0 0 0 1.69E+08 1.30E+08 - - - 2.6677 1 221125_WJC_METTL3_EV_vs_WT_F04.08685.08685.2 8.29E-09 13/24 A.AAAAAAYSDGYGR.V "sp|O43251|RFOX2_HUMAN,tr|B0QYV1|B0QYV1_HUMAN,tr|A0A0G2JRD1|A0A0G2JRD1_HUMAN,tr|A0A0G2JRA5|A0A0G2JRA5_HUMAN,tr|S4R3K7|S4R3K7_HUMAN" 5 1242.5629 1.34 43703 8685 2 1242.561177 622.2887 RNA binding protein fox-1 homolog 2 OS=Homo sapiens OX=9606 GN=RBFOX2 PE=1 SV=3 5.88 2002.1 - 1.20E+06 - - - -1.3987 - 2.852 0.636 - 675.6 1 1 0 -0.0017 13 0 0 0 3.96E+07 2.95E+07 - - - 6.4277 0.9995 221125_WJC_METTL3_EV_vs_WT_F04.08695.08695.2 0.00406 14-Sep K.SSELQAIK.T "sp|Q9UKM9|RALY_HUMAN,tr|Q5QPM0|Q5QPM0_HUMAN,tr|Q5QPL9|Q5QPL9_HUMAN" 3 874.476 1.27 43709 8695 2 874.477508 438.2453 RNA-binding protein Raly OS=Homo sapiens OX=9606 GN=RALY PE=1 SV=1 5.72 2003.4 - 1.99E+06 - - - 1.7279 - 1.971 0.38 - 414 1 2 0 0.0015 8 0 0 0 1.70E+08 1.34E+08 - - - 3.8937 0.9996 221125_WJC_METTL3_EV_vs_WT_F04.08696.08696.2 0.000418 13/22 R.LEGNTVGVEAAR[166.11].V "sp|P46060|RAGP1_HUMAN,tr|B0QYT4|B0QYT4_HUMAN,tr|B0QYT5|B0QYT5_HUMAN" 3 1224.6338 1.39 43710 8696 2 1224.630545 613.3242 Ran GTPase-activating protein 1 OS=Homo sapiens OX=9606 GN=RANGAP1 PE=1 SV=1 4.53 2003.5 - 940645 - - - -2.6457 - 2.558 0.493 - 684.1 1 2 0 -0.0032 12 0 0 0 4.58E+07 3.28E+07 - - - 5.1525 0.9673 221125_WJC_METTL3_EV_vs_WT_F04.08697.08697.2 0.00399 20-Dec R.ALANSLAC[160.03]QGK[136.11].Y "sp|P04075|ALDOA_HUMAN,tr|H3BR68|H3BR68_HUMAN,tr|J3KPS3|J3KPS3_HUMAN" 3 1139.5848 1.64 43711 8697 2 1139.575542 570.7997 Fructose-bisphosphate aldolase A OS=Homo sapiens OX=9606 GN=ALDOA PE=1 SV=2 8.27 2003.6 - 764862 - - - -8.1617 - 2.589 0.299 - 476.2 1 2 0 -0.0093 11 0 0 0 1.07E+08 6.57E+07 - - - 3.8199 0.9989 221125_WJC_METTL3_EV_vs_WT_F04.08699.08699.2 0.0247 14-Aug K.TQLEINGR.N "sp|Q9NR56|MBNL1_HUMAN,sp|Q5VZF2|MBNL2_HUMAN,sp|Q9NUK0|MBNL3_HUMAN,tr|H7C4T5|H7C4T5_HUMAN,tr|Q86VM6|Q86VM6_HUMAN,tr|C9J4T8|C9J4T8_HUMAN,tr|A0A0A0MQX8|A0A0A0MQX8_HUMAN,tr|A0A7P0T9I3|A0A7P0T9I3_HUMAN,tr|B1AKI6|B1AKI6_HUMAN,tr|C9JP00|C9JP00_HUMAN,tr|O95205|O95205_HUMAN" 11 929.493 1.48 43712 8699 2 929.491577 465.7538 Muscleblind-like protein 1 OS=Homo sapiens OX=9606 GN=MBNL1 PE=1 SV=2 5.66 2003.8 - 2.65E+07 - - - -1.5783 - 1.519 0.33 - 326.3 1 2 0 -0.0015 8 0 0 0 1.39E+09 9.36E+08 - - - 2.7387 0.998 221125_WJC_METTL3_EV_vs_WT_F04.08714.08714.2 0.117 12-Aug K.QIQQYMK[136.11].L sp|P34932|HSP74_HUMAN 1 945.4833 0.01 43720 8714 2 945.480969 473.7489 Heat shock 70 kDa protein 4 OS=Homo sapiens OX=9606 GN=HSPA4 PE=1 SV=4 8.59 2005.6 - 4.80E+06 - - - -2.5056 - 1.609 0.303 - 338.5 1 2 0 -0.0024 7 0 0 0 1.20E+06 1.05E+08 - - - 2.7852 0.9998 221125_WJC_METTL3_EV_vs_WT_F04.08717.08717.2 6.93E-08 20-Nov K.QVVQATAEQMR[166.11].L "sp|Q5T6F2|UBAP2_HUMAN,tr|A0A804HLJ4|A0A804HLJ4_HUMAN,tr|A0A804HIK1|A0A804HIK1_HUMAN,tr|A2A305|A2A305_HUMAN,tr|A0A804HLD2|A0A804HLD2_HUMAN" 5 1269.6375 1.08 43723 8717 2 1269.635835 635.826 Ubiquitin-associated protein 2 OS=Homo sapiens OX=9606 GN=UBAP2 PE=1 SV=1 6 2006 - 593389 - - - -1.3035 - 2.372 0.427 - 600.9 1 2 0 -0.0017 11 0 0 0 9.19E+06 8.53E+06 - - - 4.5309 0.9989 221125_WJC_METTL3_EV_vs_WT_F04.08720.08720.2 0.0797 14-Aug K.STDAYELK.L "sp|P48594|SPB4_HUMAN,sp|P29508|SPB3_HUMAN,tr|H0Y5H9|H0Y5H9_HUMAN" 3 925.4393 82.74 43724 8720 2 925.437818 463.7269 Serpin B4 OS=Homo sapiens OX=9606 GN=SERPINB4 PE=1 SV=2 4.37 2006.4 - 9.23E+06 - - - -1.5765 - 1.66 0.297 - 300 1 2 0 -0.0015 8 0 0 0 2.46E+08 2.98E+06 - - - 2.7627 0.9937 221125_WJC_METTL3_EV_vs_WT_F04.08722.08722.2 0.0139 22-Sep K.ALETDSVSGVSK[136.11].Q "sp|Q15022|SUZ12_HUMAN,tr|J3QQW9|J3QQW9_HUMAN" 2 1199.6125 0.45 43726 8722 2 1199.60788 600.8135 Polycomb protein SUZ12 OS=Homo sapiens OX=9606 GN=SUZ12 PE=1 SV=3 4.37 2006.6 - 364746 - - - -3.8487 - 1.857 0.265 - 182.6 1 2 0 -0.0046 12 0 0 0 4.63E+06 1.03E+07 - - - 2.6254 0.9546 221125_WJC_METTL3_EV_vs_WT_F04.08725.08725.2 1.75 14-Aug K.EGIVALR[166.11]R[166.11].A sp|P40227|TCPZ_HUMAN 1 932.567 0.36 43727 8725 2 932.566073 467.2908 T-complex protein 1 subunit zeta OS=Homo sapiens OX=9606 GN=CCT6A PE=1 SV=3 9.7 2007 - 3.34E+06 - - - -1.0359 - 1.158 0.054 - 192.1 2 2 0 -0.001 8 0 0 0 2.91E+07 8.07E+07 - - - -0.2525 0.9987 221125_WJC_METTL3_EV_vs_WT_F04.08728.08728.2 5.71E-05 18-Nov K.VVGNPC[160.03]PIC[160.03]R.D sp|Q9Y676|RT18B_HUMAN 1 1170.5638 0.79 43730 8728 2 1170.568198 586.2892 "28S ribosomal protein S18b, mitochondrial OS=Homo sapiens OX=9606 GN=MRPS18B PE=1 SV=1" 8.04 2007.4 - 1.00E+06 - - - 3.7708 - 1.77 0.505 - 499.5 1 2 0 0.0044 10 0 0 0 2.52E+07 3.21E+07 - - - 4.3633 0.9966 221125_WJC_METTL3_EV_vs_WT_F04.08729.08729.2 8.01E-06 20-Dec K.LASAAYPDPSK[136.11].Q "sp|P54577|SYYC_HUMAN,tr|A0A6Q8PFX2|A0A6Q8PFX2_HUMAN" 2 1126.575 0.63 43731 8729 2 1126.568972 564.2948 "Tyrosine--tRNA ligase, cytoplasmic OS=Homo sapiens OX=9606 GN=YARS1 PE=1 SV=4" 5.83 2007.5 - 860488 - - - -5.341 - 2.462 0.425 - 528.1 1 2 0 -0.006 11 0 0 0 2.88E+07 4.58E+07 - - - 4.6155 0.9995 221125_WJC_METTL3_EV_vs_WT_F04.08733.08733.2 6.76E-05 20-Nov R.ALANSLAC[160.03]QGK.Y "sp|P04075|ALDOA_HUMAN,tr|H3BR68|H3BR68_HUMAN,tr|J3KPS3|J3KPS3_HUMAN" 3 1131.5706 1.64 43733 8733 2 1131.568249 566.7926 Fructose-bisphosphate aldolase A OS=Homo sapiens OX=9606 GN=ALDOA PE=1 SV=2 8.27 2008 - 4.50E+06 - - - -2.1156 - 2.125 0.412 - 357.2 1 2 0 -0.0024 11 0 0 0 1.08E+08 6.57E+07 - - - 4.1224 0.9996 221125_WJC_METTL3_EV_vs_WT_F04.08734.08734.2 0.032 12-Aug K.YDEEFQR[166.11].Y sp|P55060|XPO2_HUMAN 1 995.4224 0.94 43734 8734 2 995.421815 498.7185 Exportin-2 OS=Homo sapiens OX=9606 GN=CSE1L PE=1 SV=3 4.14 2008.2 - 967454 - - - -0.5827 - 1.623 0.353 - 220.2 1 2 0 -0.0006 7 0 0 0 1.61E+07 1.70E+07 - - - 3.1825 1 221125_WJC_METTL3_EV_vs_WT_F04.08741.08741.2 1.05E-05 18-Nov K.EGALC[160.03]EENMR[166.11].G sp|P13639|EF2_HUMAN 1 1217.5044 0.46 43739 8741 2 1217.501266 609.7595 Elongation factor 2 OS=Homo sapiens OX=9606 GN=EEF2 PE=1 SV=4 4.25 2008.9 - 1.14E+06 - - - -2.5963 - 2.397 0.64 - 512.3 1 2 0 -0.0032 10 0 0 0 3.91E+07 8.42E+07 - - - 6.2073 0.9347 221125_WJC_METTL3_EV_vs_WT_F04.08743.08743.2 1.3 20-Aug R.TSGQEATESAK[136.11].Q sp|Q9ULL8|SHRM4_HUMAN 1 1115.5186 0.001 43741 8743 2 1115.514199 558.7666 Protein Shroom4 OS=Homo sapiens OX=9606 GN=SHROOM4 PE=1 SV=3 4.53 2009.2 - 1.52E+06 - - - -3.9426 - 1.236 0.16 - 172 1 2 0 -0.0044 11 0 0 0 0.00E+00 4.32E+07 - - - 0.7946 0.9995 221125_WJC_METTL3_EV_vs_WT_F04.08750.08750.2 0.0171 12-Jul K.YDEEFQR.Y sp|P55060|XPO2_HUMAN 1 985.4141 0.97 43746 8750 2 985.413297 493.7143 Exportin-2 OS=Homo sapiens OX=9606 GN=CSE1L PE=1 SV=3 4.14 2010 - 927146 - - - -0.8403 - 1.631 0.335 - 186.5 1 2 0 -0.0008 7 0 0 0 1.61E+07 1.66E+07 - - - 3.0651 0.9976 221125_WJC_METTL3_EV_vs_WT_F04.08751.08751.2 0.411 16-Aug K.AQLNETLTK.L "sp|Q86UP2|KTN1_HUMAN,tr|B7Z6P3|B7Z6P3_HUMAN,tr|H0YJP2|H0YJP2_HUMAN,tr|G3V4Y7|G3V4Y7_HUMAN" 4 1016.5502 2.04 43747 8751 2 1016.548514 509.2824 Kinectin OS=Homo sapiens OX=9606 GN=KTN1 PE=1 SV=1 6.05 2010.2 - 309461 - - - -1.6831 - 1.642 0.218 - 190.2 1 2 0 -0.0017 9 0 0 0 4.27E+07 2.09E+07 - - - 2.0853 0.9999 221125_WJC_METTL3_EV_vs_WT_F04.08753.08753.2 0.0082 20-Dec R.VEGSETPYVDR[166.11].T sp|Q96DF8|ESS2_HUMAN 1 1260.5862 2.04 43748 8753 2 1260.584756 631.3004 Splicing factor ESS-2 homolog OS=Homo sapiens OX=9606 GN=ESS2 PE=1 SV=1 4.14 2010.5 - 770215 - - - -1.1185 - 2.721 0.471 - 579.5 1 2 0 -0.0014 11 0 0 0 1.00E+08 4.92E+07 - - - 5.2273 0.9788 221125_WJC_METTL3_EV_vs_WT_F04.08755.08755.2 0.0217 14-Jul Q.EFC[160.03]DYGTK[136.11].E "sp|Q86U44|MTA70_HUMAN,tr|H0YFV6|H0YFV6_HUMAN" 2 1026.4208 0.02 43749 8755 2 1026.420089 514.2177 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 4.37 2010.7 - 2.29E+06 - - - -0.6898 - 1.171 0.532 - 255 1 1 0 -0.0007 8 0 0 0 3.40E+06 1.88E+08 - - - 3.4462 1 221125_WJC_METTL3_EV_vs_WT_F04.08756.08756.2 0.000114 18-Dec K.EGALC[160.03]EENMR.G sp|P13639|EF2_HUMAN 1 1207.4962 0.47 43750 8756 2 1207.494851 604.7554 Elongation factor 2 OS=Homo sapiens OX=9606 GN=EEF2 PE=1 SV=4 4.25 2010.9 - 1.27E+06 - - - -1.0816 - 2.591 0.603 - 622.1 1 2 0 -0.0013 10 0 0 0 3.91E+07 8.41E+07 - - - 6.1518 0.9996 221125_WJC_METTL3_EV_vs_WT_F04.08759.08759.2 0.000249 14-Sep R.SSYLESPR.G "sp|P49750|YLPM1_HUMAN,tr|H0YIQ2|H0YIQ2_HUMAN,tr|F8VU51|F8VU51_HUMAN" 3 937.4505 1.32 43752 8759 2 937.448529 469.7325 YLP motif-containing protein 1 OS=Homo sapiens OX=9606 GN=YLPM1 PE=1 SV=4 5.72 2011.2 - 1.40E+06 - - - -2.1142 - 1.821 0.446 - 277.4 1 2 0 -0.002 8 0 0 0 3.33E+07 2.53E+07 - - - 4.1423 0.9989 221125_WJC_METTL3_EV_vs_WT_F04.08761.08761.2 0.0453 14-Oct R.R[166.11]LNVAITR[166.11].A "sp|P51530|DNA2_HUMAN,sp|Q92900|RENT1_HUMAN,tr|F8VR31|F8VR31_HUMAN,tr|H0Y455|H0Y455_HUMAN" 4 961.5936 1 43753 8761 2 961.593387 481.8041 DNA replication ATP-dependent helicase\nuclease DNA2 OS=Homo sapiens OX=9606 GN=DNA2 PE=1 SV=3 12 2011.4 - 638580 - - - -0.2101 - 1.489 0.281 - 203.9 1 2 0 -0.0002 8 0 0 0 1.06E+07 1.06E+07 - - - 2.3171 0.9996 221125_WJC_METTL3_EV_vs_WT_F04.08762.08762.2 0.000686 18-Sep R.TESTPITAVK[136.11].Q sp|Q9Y678|COPG1_HUMAN 1 1053.5797 73.81 43754 8762 2 1053.580387 527.7971 Coatomer subunit gamma-1 OS=Homo sapiens OX=9606 GN=COPG1 PE=1 SV=1 5.66 2011.5 - 556236 - - - 0.6141 - 1.712 0.401 - 247.9 1 2 0 0.0006 10 0 0 0 1.37E+09 1.85E+07 - - - 3.5034 0.9998 221125_WJC_METTL3_EV_vs_WT_F04.08764.08764.2 7.94E-05 18-Oct R.SDGTSLYATR[166.11].D sp|Q5T160|SYRM_HUMAN 1 1079.5123 0.67 43756 8764 2 1079.513452 540.7634 "Probable arginine--tRNA ligase, mitochondrial OS=Homo sapiens OX=9606 GN=RARS2 PE=1 SV=1" 5.55 2011.8 - 487349 - - - 1.0922 - 2.093 0.484 - 547 1 2 0 0.0012 10 0 0 0 4.89E+06 7.31E+06 - - - 4.6771 0.986 221125_WJC_METTL3_EV_vs_WT_F04.08765.08765.2 0.247 16-Jun R.IQPDYPAER.S "sp|Q9H0E3|SP130_HUMAN,tr|A0A2R8YDB8|A0A2R8YDB8_HUMAN,tr|H7BXF5|H7BXF5_HUMAN" 3 1087.5298 2.69 43757 8765 2 1087.52828 544.7722 Histone deacetylase complex subunit SAP130 OS=Homo sapiens OX=9606 GN=SAP130 PE=1 SV=1 4.37 2011.9 - 351986 - - - -1.4197 - 1.392 0.089 - 107.1 1 2 0 -0.0015 9 0 0 0 5.79E+06 2.15E+06 - - - 0.6547 0.9951 221125_WJC_METTL3_EV_vs_WT_F04.08766.08766.2 0.053 12-Jun K.K[136.11]SLVAFK[136.11].L "sp|P15927|RFA2_HUMAN,tr|Q5TEJ7|Q5TEJ7_HUMAN" 2 807.5189 1.01 43758 8766 2 807.520673 404.7667 Replication protein A 32 kDa subunit OS=Homo sapiens OX=9606 GN=RPA2 PE=1 SV=1 10 2012.1 - 347964 - - - 2.1647 - 1.392 0.236 - 135.3 1 2 0 0.0017 7 0 0 0 6.43E+06 6.36E+06 - - - 1.8315 0.9995 221125_WJC_METTL3_EV_vs_WT_F04.08770.08770.2 0.0438 16-Oct R.LEALDANSR[166.11].K "sp|P09496|CLCA_HUMAN,tr|F8WF69|F8WF69_HUMAN" 2 997.5068 0.58 43760 8770 2 997.506962 499.7607 Clathrin light chain A OS=Homo sapiens OX=9606 GN=CLTA PE=1 SV=1 4.37 2012.5 - 2.17E+06 - - - 0.1694 - 2.168 0.236 - 389 1 2 0 0.0002 9 0 0 0 2.47E+07 4.25E+07 - - - 3.0227 0.9996 221125_WJC_METTL3_EV_vs_WT_F04.08771.08771.2 0.212 16-Sep R.DAEDAVYGR[166.11].D "sp|Q07955|SRSF1_HUMAN,tr|J3KTL2|J3KTL2_HUMAN" 2 1004.4439 1.23 43761 8771 2 1004.443197 503.2292 Serine\arginine-rich splicing factor 1 OS=Homo sapiens OX=9606 GN=SRSF1 PE=1 SV=2 4.03 2012.6 - 1.50E+06 - - - -0.6591 - 2.004 0.317 - 343.2 1 2 0 -0.0007 9 0 0 0 2.90E+07 2.35E+07 - - - 3.3932 0.9998 221125_WJC_METTL3_EV_vs_WT_F04.08772.08772.2 0.001 13/24 R.GAGSAMSTDAYPK.N "sp|O95721|SNP29_HUMAN,tr|C9JAF7|C9JAF7_HUMAN" 2 1254.5551 1.51 43762 8772 2 1254.557034 628.2848 Synaptosomal-associated protein 29 OS=Homo sapiens OX=9606 GN=SNAP29 PE=1 SV=1 5.83 2012.7 - 407327 - - - 1.5798 - 2.434 0.544 - 415.6 1 2 0 0.002 13 0 0 0 8.44E+06 5.61E+06 - - - 5.3414 0.9998 221125_WJC_METTL3_EV_vs_WT_F04.08773.08773.2 0.00402 18-Oct K.TTSPLEEEER[166.11].E "sp|Q9UKV3|ACINU_HUMAN,tr|S4R3H4|S4R3H4_HUMAN,tr|E7EQT4|E7EQT4_HUMAN" 3 1199.5545 1.35 43763 8773 2 1199.554674 600.7845 Apoptotic chromatin condensation inducer in the nucleus OS=Homo sapiens OX=9606 GN=ACIN1 PE=1 SV=2 4.09 2012.8 - 271310 - - - 0.1184 - 1.965 0.398 - 465.5 1 2 0 0.0001 10 0 0 0 1.04E+07 7.66E+06 - - - 3.8661 0.9998 221125_WJC_METTL3_EV_vs_WT_F04.08776.08776.2 1.01E-06 20-Dec K.AATAAADFTAK.V sp|Q9Y3F4|STRAP_HUMAN 1 1036.5189 7.35 43764 8776 2 1036.520422 519.2667 Serine-threonine kinase receptor-associated protein OS=Homo sapiens OX=9606 GN=STRAP PE=1 SV=1 5.88 2013.2 - 1.67E+06 - - - 1.4443 - 2.239 0.532 - 735 1 2 0 0.0015 11 0 0 0 9.67E+07 1.32E+07 - - - 5.1504 0.9996 221125_WJC_METTL3_EV_vs_WT_F04.08777.08777.3 0.00227 Oct-36 R.VLSGHLMQTR[166.11].D "sp|Q6PJT7|ZC3HE_HUMAN,tr|G3V4R5|G3V4R5_HUMAN,tr|H0YJA2|H0YJA2_HUMAN,tr|G3V411|G3V411_HUMAN" 4 1150.6156 1.86 43765 8777 3 1150.614374 384.5458 Zinc finger CCCH domain-containing protein 14 OS=Homo sapiens OX=9606 GN=ZC3H14 PE=1 SV=1 9.73 2013.4 - 297742 - - - -1.0933 - 1.824 0.343 - 131.9 1 2 0 -0.0013 10 0 0 0 1.86E+07 1.00E+07 - - - 4.119 0.9991 221125_WJC_METTL3_EV_vs_WT_F04.08778.08778.3 0.271 Jul-32 R.IIC[160.03]HSYLER.L sp|Q9NQS7|INCE_HUMAN 1 1189.5914 1.04 43766 8778 3 1189.592672 397.5377 Inner centromere protein OS=Homo sapiens OX=9606 GN=INCENP PE=1 SV=3 6.74 2013.5 - 286023 - - - 1.0878 - 1.702 0.303 - 47.6 1 2 0 0.0013 9 0 0 0 1.37E+07 1.31E+07 - - - 3.5205 0.9956 221125_WJC_METTL3_EV_vs_WT_F04.08783.08783.2 2.74 14-Jul R.DLEGAVSR[166.11].L "sp|Q9H307|PININ_HUMAN,tr|G3V5F0|G3V5F0_HUMAN,tr|G3V579|G3V579_HUMAN" 3 855.4326 1.12 43769 8783 2 855.433122 428.7236 Pinin OS=Homo sapiens OX=9606 GN=PNN PE=1 SV=5 4.37 2014.2 - 1.28E+06 - - - 0.65 - 1.339 0.186 - 171 1 2 0 0.0006 8 0 0 0 2.82E+07 2.52E+07 - - - 1.295 0.9995 221125_WJC_METTL3_EV_vs_WT_F04.08784.08784.3 0.0316 Dec-32 R.IIC[160.03]HSYLER[166.11].L sp|Q9NQS7|INCE_HUMAN 1 1199.5996 2.36 43770 8784 3 1199.600283 400.8738 Inner centromere protein OS=Homo sapiens OX=9606 GN=INCENP PE=1 SV=3 6.74 2014.3 - 479751 - - - 0.5293 - 1.87 0.308 - 161.3 1 2 0 0.0006 9 0 0 0 3.35E+07 1.42E+07 - - - 3.8602 0.9233 221125_WJC_METTL3_EV_vs_WT_F04.08785.08785.2 4.7 12-Jun K.DISC[160.03]LNR[166.11].D "sp|Q3ZCQ8|TIM50_HUMAN,tr|M0R1Y4|M0R1Y4_HUMAN,tr|M0R2F8|M0R2F8_HUMAN,tr|M0R003|M0R003_HUMAN,tr|M0R2Q2|M0R2Q2_HUMAN" 5 886.4206 1.2 43771 8785 2 886.422108 444.2176 Mitochondrial import inner membrane translocase subunit TIM50 OS=Homo sapiens OX=9606 GN=TIMM50 PE=1 SV=2 5.83 2014.4 - 536415 - - - 1.6775 - 0.971 0.099 - 131.2 1 2 0 0.0015 7 0 0 0 1.34E+07 1.12E+07 - - - -0.3215 0.9979 221125_WJC_METTL3_EV_vs_WT_F04.08791.08791.2 0.0109 16-Aug R.EGSLVINSK.N sp|Q9Y5B9|SP16H_HUMAN 1 945.5131 0.93 43775 8791 2 945.514633 473.7638 FACT complex subunit SPT16 OS=Homo sapiens OX=9606 GN=SUPT16H PE=1 SV=1 6.1 2015.1 - 1.10E+06 - - - 1.6097 - 1.531 0.27 - 217.3 1 2 0 0.0015 9 0 0 0 3.83E+07 4.10E+07 - - - 2.267 0.9935 221125_WJC_METTL3_EV_vs_WT_F04.08792.08792.2 0.35 12-Jun K.DISC[160.03]LNR.D "sp|Q3ZCQ8|TIM50_HUMAN,tr|M0R1Y4|M0R1Y4_HUMAN,tr|M0R2F8|M0R2F8_HUMAN,tr|M0R003|M0R003_HUMAN,tr|M0R2Q2|M0R2Q2_HUMAN" 5 876.4124 1 43776 8792 2 876.413193 439.2135 Mitochondrial import inner membrane translocase subunit TIM50 OS=Homo sapiens OX=9606 GN=TIMM50 PE=1 SV=2 5.83 2015.2 - 656788 - - - 0.9607 - 1.315 0.162 - 134.7 1 2 0 0.0008 7 0 0 0 1.34E+07 1.34E+07 - - - 1.1049 0.9989 221125_WJC_METTL3_EV_vs_WT_F04.08793.08793.2 0.0076 16-Aug R.EGSLVINSK[136.11].N sp|Q9Y5B9|SP16H_HUMAN 1 953.5273 0.93 43777 8793 2 953.528523 477.7709 FACT complex subunit SPT16 OS=Homo sapiens OX=9606 GN=SUPT16H PE=1 SV=1 6.1 2015.3 - 1.24E+06 - - - 1.2711 - 1.686 0.285 - 235.3 1 2 0 0.0012 9 0 0 0 3.82E+07 4.10E+07 - - - 2.6568 0.9992 221125_WJC_METTL3_EV_vs_WT_F04.08795.08795.2 4.51E-05 20-Sep R.YPGSPGSYAAR[166.11].Q "sp|Q16769|QPCT_HUMAN,tr|A0A3B3IUD5|A0A3B3IUD5_HUMAN" 2 1134.5333 3.35 43779 8795 2 1134.536177 568.2739 Glutaminyl-peptide cyclotransferase OS=Homo sapiens OX=9606 GN=QPCT PE=1 SV=1 8.59 2015.5 - 444570 - - - 2.4979 - 1.634 0.463 - 214.5 1 2 0 0.0028 11 0 0 0 4.38E+07 1.31E+07 - - - 3.7882 0.9888 221125_WJC_METTL3_EV_vs_WT_F04.08799.08799.2 0.602 12-Aug K.HVAYIIR.S "sp|P31025|LCN1_HUMAN,sp|Q5VSP4|LC1L1_HUMAN" 2 870.5076 13.78 43781 8799 2 870.508369 436.2611 Lipocalin-1 OS=Homo sapiens OX=9606 GN=LCN1 PE=1 SV=1 8.75 2016.1 - 422537 - - - 0.9156 - 1.338 0.1 - 232.5 1 2 0 0.0008 7 0 0 0 1.69E+07 1.23E+06 - - - 0.702 0.9989 221125_WJC_METTL3_EV_vs_WT_F04.08800.08800.2 0.0546 14-Sep R.C[160.03]NVENLPR[166.11].S "sp|Q92896|GSLG1_HUMAN,tr|H3BM42|H3BM42_HUMAN" 2 1010.4843 1.83 43782 8800 2 1010.486788 506.2494 Golgi apparatus protein 1 OS=Homo sapiens OX=9606 GN=GLG1 PE=1 SV=2 5.99 2016.2 - 531590 - - - 2.478 - 1.868 0.337 - 391.8 1 2 0 0.0025 8 0 0 0 1.43E+07 7.82E+06 - - - 3.4139 0.9937 221125_WJC_METTL3_EV_vs_WT_F04.08801.08801.2 0.144 14-Jul K.APTNIVYK.L "sp|P15927|RFA2_HUMAN,tr|Q5TEJ7|Q5TEJ7_HUMAN" 2 904.5018 1.24 43783 8801 2 904.502986 453.2582 Replication protein A 32 kDa subunit OS=Homo sapiens OX=9606 GN=RPA2 PE=1 SV=1 8.63 2016.3 - 409724 - - - 1.2913 - 1.457 0.145 - 170.4 1 2 0 0.0012 8 0 0 0 6.61E+06 5.32E+06 - - - 1.2467 0.9978 221125_WJC_METTL3_EV_vs_WT_F04.08807.08807.2 0.00158 16-Sep K.EQLQGLNDR.F "sp|Q16352|AINX_HUMAN,sp|P07197|NFM_HUMAN,tr|E7ESP9|E7ESP9_HUMAN,tr|E7EMV2|E7EMV2_HUMAN" 4 1071.5309 1.27 43788 8807 2 1071.532625 536.7727 Alpha-internexin OS=Homo sapiens OX=9606 GN=INA PE=1 SV=2 4.37 2017.1 - 1.46E+06 - - - 1.6229 - 1.838 0.192 - 428 1 2 0 0.0017 9 0 0 0 2.16E+07 1.70E+07 - - - 2.2195 0.978 221125_WJC_METTL3_EV_vs_WT_F04.08809.08809.2 1.46 14-Jun R.DLEGAVSR.L "sp|Q9H307|PININ_HUMAN,tr|G3V5F0|G3V5F0_HUMAN,tr|G3V579|G3V579_HUMAN" 3 845.4243 1.14 43789 8809 2 845.425271 423.7194 Pinin OS=Homo sapiens OX=9606 GN=PNN PE=1 SV=5 4.37 2017.3 - 1.37E+06 - - - 1.1533 - 1.275 0.093 - 117.5 2 2 0 0.001 8 0 0 0 2.82E+07 2.48E+07 - - - 0.3258 0.999 221125_WJC_METTL3_EV_vs_WT_F04.08810.08810.2 0.00346 14-Jul K.AIETFSGK.V sp|Q9NZI8|IF2B1_HUMAN 1 851.4389 0.54 43790 8810 2 851.440284 426.7267 Insulin-like growth factor 2 mRNA-binding protein 1 OS=Homo sapiens OX=9606 GN=IGF2BP1 PE=1 SV=2 6.05 2017.4 - 1.09E+06 - - - 1.6454 - 1.418 0.393 - 170.2 1 2 0 0.0014 8 0 0 0 1.92E+07 3.54E+07 - - - 2.9966 0.9741 221125_WJC_METTL3_EV_vs_WT_F04.08811.08811.2 1.11 12-Jul R.TIELDGK.R "sp|P61006|RAB8A_HUMAN,sp|Q9H0U4|RAB1B_HUMAN,sp|P62820|RAB1A_HUMAN,sp|Q92930|RAB8B_HUMAN,sp|Q92928|RAB1C_HUMAN,tr|H0YMN7|H0YMN7_HUMAN,tr|H0YNE9|H0YNE9_HUMAN,tr|E9PLD0|E9PLD0_HUMAN" 8 774.4123 1.97 43791 8811 2 774.413728 388.2134 Ras-related protein Rab-8A OS=Homo sapiens OX=9606 GN=RAB8A PE=1 SV=1 4.37 2017.5 - 664970 - - - 1.8001 - 1.281 0.085 - 197.5 1 2 0 0.0014 7 0 0 0 9.72E+06 4.92E+06 - - - 0.453 0.991 221125_WJC_METTL3_EV_vs_WT_F04.08814.08814.2 0.163 16-Aug K.DAHLLVESK.N "sp|P42704|LPPRC_HUMAN,tr|A0A804HI14|A0A804HI14_HUMAN,tr|A0A804HL40|A0A804HL40_HUMAN,tr|A0A804HKJ0|A0A804HKJ0_HUMAN,tr|A0A804HIN4|A0A804HIN4_HUMAN,tr|A0A804HLG8|A0A804HLG8_HUMAN,tr|A0A804HIV5|A0A804HIV5_HUMAN,tr|A0A804HHY9|A0A804HHY9_HUMAN,tr|A0A804HJH8|A0A804HJH8_HUMAN,tr|B8ZZ38|B8ZZ38_HUMAN,tr|A0A804HI40|A0A804HI40_HUMAN,tr|A0A804HJZ1|A0A804HJZ1_HUMAN,tr|C9JCA9|C9JCA9_HUMAN,tr|A0A804HIQ7|A0A804HIQ7_HUMAN,tr|A0A804HK30|A0A804HK30_HUMAN,tr|A0A804HKI2|A0A804HKI2_HUMAN,tr|A0A804HJI0|A0A804HJI0_HUMAN,tr|A0A804HIG4|A0A804HIG4_HUMAN,tr|A0A804HK02|A0A804HK02_HUMAN" 19 1010.5397 0.19 43794 8814 2 1010.540842 506.2771 "Leucine-rich PPR motif-containing protein, mitochondrial OS=Homo sapiens OX=9606 GN=LRPPRC PE=1 SV=3" 5.32 2017.8 - 479352 - - - 1.1697 - 1.392 0.128 - 204.5 1 2 0 0.0012 9 0 0 0 2.83E+07 1.49E+08 - - - 0.9429 0.9793 221125_WJC_METTL3_EV_vs_WT_F04.08816.08816.2 0.000242 20-Jul F.VTFENSADADR.A "sp|O43251|RFOX2_HUMAN,sp|Q9NWB1|RFOX1_HUMAN,tr|A0A6Q8PGE0|A0A6Q8PGE0_HUMAN,tr|A0A6Q8PH77|A0A6Q8PH77_HUMAN,tr|A0A286YEU2|A0A286YEU2_HUMAN,tr|A0A087X2B1|A0A087X2B1_HUMAN,tr|F8VR27|F8VR27_HUMAN,tr|B7Z1U7|B7Z1U7_HUMAN,tr|B0QYV1|B0QYV1_HUMAN,tr|A0A6Q8PHA3|A0A6Q8PHA3_HUMAN,tr|F8VZY7|F8VZY7_HUMAN,tr|B0QYY4|B0QYY4_HUMAN,tr|J3KNW3|J3KNW3_HUMAN,tr|F8VZG9|F8VZG9_HUMAN,tr|F8VRS4|F8VRS4_HUMAN,tr|A0A6Q8PFM4|A0A6Q8PFM4_HUMAN,tr|S4R469|S4R469_HUMAN,tr|A0A804HKG7|A0A804HKG7_HUMAN,tr|A0A0G2JRD1|A0A0G2JRD1_HUMAN,tr|A0A0G2JRA5|A0A0G2JRA5_HUMAN,tr|A0A804HJM2|A0A804HJM2_HUMAN,tr|I3L1D4|I3L1D4_HUMAN,tr|B0QYY7|B0QYY7_HUMAN,tr|A0A0G2JSB3|A0A0G2JSB3_HUMAN,tr|S4R3K7|S4R3K7_HUMAN" 25 1223.5418 1.55 43796 8816 2 1223.54138 612.7782 RNA binding protein fox-1 homolog 2 OS=Homo sapiens OX=9606 GN=RBFOX2 PE=1 SV=3 4.03 2018.1 - 145456 - - - -0.38 - 1.501 0.442 - 147.4 1 1 0 -0.0005 11 0 0 0 2.87E+06 1.86E+06 - - - 3.4041 0.9953 221125_WJC_METTL3_EV_vs_WT_F04.08820.08820.2 0.373 14-Aug R.NIAPNISR[166.11].A "sp|Q9BXP5|SRRT_HUMAN,tr|H7C1K0|H7C1K0_HUMAN,tr|H7C3A1|H7C3A1_HUMAN" 3 893.4958 1.72 43798 8820 2 893.497438 447.7552 Serrate RNA effector molecule homolog OS=Homo sapiens OX=9606 GN=SRRT PE=1 SV=1 9.75 2018.6 - 2.27E+06 - - - 1.7941 - 1.541 0.18 - 243.7 1 2 0 0.0016 8 0 0 0 8.16E+07 4.75E+07 - - - 1.6742 0.9998 221125_WJC_METTL3_EV_vs_WT_F04.08821.08821.2 1.98E-05 18-Aug K.GEGLTPYQGK.K sp|Q8N2G6|ZCH24_HUMAN 1 1048.5189 0.78 43799 8821 2 1048.519098 525.2667 Zinc finger CCHC domain-containing protein 24 OS=Homo sapiens OX=9606 GN=ZCCHC24 PE=1 SV=1 6 2018.7 - 1.86E+06 - - - 0.165 - 1.804 0.496 - 339.6 1 2 0 0.0002 10 0 0 0 4.43E+07 5.67E+07 - - - 4.3513 0.999 221125_WJC_METTL3_EV_vs_WT_F04.08822.08822.2 0.0217 12-Aug K.HAIPIIK[136.11].E "sp|O00571|DDX3X_HUMAN,sp|O15523|DDX3Y_HUMAN,tr|A0A2R8YFR4|A0A2R8YFR4_HUMAN,tr|A0A2R8YCW1|A0A2R8YCW1_HUMAN,tr|A0A2R8YDH3|A0A2R8YDH3_HUMAN,tr|A0A2R8YDT5|A0A2R8YDT5_HUMAN,tr|A0A2R8Y645|A0A2R8Y645_HUMAN,tr|A0A2R8YF78|A0A2R8YF78_HUMAN,tr|C9J8G5|C9J8G5_HUMAN,tr|A0A2R8Y4D2|A0A2R8Y4D2_HUMAN,tr|A0A0D9SFB3|A0A0D9SFB3_HUMAN,tr|A0A2R8YFS5|A0A2R8YFS5_HUMAN,tr|A0A0D9SF53|A0A0D9SF53_HUMAN,tr|C9J081|C9J081_HUMAN,tr|A0A2R8Y5G6|A0A2R8Y5G6_HUMAN,tr|A0A2R8Y7T2|A0A2R8Y7T2_HUMAN,tr|A0A0D9SG12|A0A0D9SG12_HUMAN,tr|F6S8Q4|F6S8Q4_HUMAN,tr|A0A2U3TZJ9|A0A2U3TZJ9_HUMAN,tr|A0A2R8Y4A4|A0A2R8Y4A4_HUMAN" 20 798.5207 1.13 43800 8822 2 798.521653 400.2676 ATP-dependent RNA helicase DDX3X OS=Homo sapiens OX=9606 GN=DDX3X PE=1 SV=3 8.76 2018.7 - 2.04E+06 - - - 1.1822 - 1.723 0.26 - 300.5 1 2 0 0.0009 7 0 0 0 1.89E+08 1.67E+08 - - - 2.685 0.9425 221125_WJC_METTL3_EV_vs_WT_F04.08824.08824.2 11.4 12-Jun K.TKPIWTR.N "sp|Q58FF8|H90B2_HUMAN,sp|Q58FG0|HS905_HUMAN,sp|P08238|HS90B_HUMAN,sp|Q58FF6|H90B4_HUMAN,sp|P07900|HS90A_HUMAN,sp|Q14568|HS902_HUMAN" 6 900.5181 0.89 43802 8824 2 900.51778 451.2663 Putative heat shock protein HSP 90-beta 2 OS=Homo sapiens OX=9606 GN=HSP90AB2P PE=1 SV=2 11 2018.9 - 1.01E+06 - - - -0.3964 - 1.145 0.03 - 105.8 3 2 0 -0.0004 7 0 0 0 6.08E+07 6.81E+07 - - - -0.5216 0.9984 221125_WJC_METTL3_EV_vs_WT_F04.08830.08830.2 0.000769 16-Jul K.VDPEIQNVK.A sp|P35908|K22E_HUMAN 1 1040.5502 2930.85 43806 8830 2 1040.551986 521.2824 "Keratin, type II cytoskeletal 2 epidermal OS=Homo sapiens OX=9606 GN=KRT2 PE=1 SV=2" 4.37 2019.7 - 3.98E+07 - - - 1.6924 - 1.459 0.327 - 192.2 1 2 0 0.0018 9 0 0 0 5.74E+09 1.96E+06 - - - 2.5485 0.9444 221125_WJC_METTL3_EV_vs_WT_F04.08831.08831.2 0.135 12-Oct D.PEIQNVK.A sp|P35908|K22E_HUMAN 1 826.4549 432.23 43807 8831 2 826.456417 414.2347 "Keratin, type II cytoskeletal 2 epidermal OS=Homo sapiens OX=9606 GN=KRT2 PE=1 SV=2" 6.43 2019.8 - 1.30E+06 - - - 1.8743 - 2.053 0.243 - 327.2 1 1 0 0.0015 7 0 0 0 1.78E+08 4.12E+05 - - - 3.1145 0.9975 221125_WJC_METTL3_EV_vs_WT_F04.08833.08833.2 0.313 12-Sep R.HLILPEK[136.11].Y "sp|O75643|U520_HUMAN,tr|A0A494C1A5|A0A494C1A5_HUMAN" 2 856.5262 2.36 43809 8833 2 856.527261 429.2704 U5 small nuclear ribonucleoprotein 200 kDa helicase OS=Homo sapiens OX=9606 GN=SNRNP200 PE=1 SV=2 6.75 2020 - 658845 - - - 1.2516 - 1.625 0.186 - 416.5 1 2 0 0.0011 7 0 0 0 5.23E+07 2.22E+07 - - - 1.9528 0.9804 221125_WJC_METTL3_EV_vs_WT_F04.08836.08836.2 0.625 14-Jun K.NSSNFIER[166.11].R "sp|Q9UBW7|ZMYM2_HUMAN,tr|A0A087X151|A0A087X151_HUMAN" 2 975.4649 0.27 43812 8836 2 975.465751 488.7397 Zinc finger MYM-type protein 2 OS=Homo sapiens OX=9606 GN=ZMYM2 PE=1 SV=1 6 2020.4 - 578103 - - - 0.8427 - 1.051 0.151 - 94.6 1 2 0 0.0008 8 0 0 0 7.91E+06 2.92E+07 - - - 0.306 0.9995 221125_WJC_METTL3_EV_vs_WT_F04.08837.08837.2 0.00122 20-Sep R.LDTGPQSLSGK.S "sp|P35269|T2FA_HUMAN,tr|M0QXD6|M0QXD6_HUMAN" 2 1101.5666 0.75 43813 8837 2 1101.567415 551.7906 General transcription factor IIF subunit 1 OS=Homo sapiens OX=9606 GN=GTF2F1 PE=1 SV=2 5.84 2020.5 - 443610 - - - 0.7371 - 1.818 0.331 - 191.1 1 2 0 0.0008 11 0 0 0 1.72E+07 2.29E+07 - - - 3.1025 0.9932 221125_WJC_METTL3_EV_vs_WT_F04.08838.08838.2 0.0399 18-Jul R.SSILAGGQPR[166.11].W "sp|Q9BYB4|GNB1L_HUMAN,tr|C9JPQ6|C9JPQ6_HUMAN" 2 994.5435 0.54 43814 8838 2 994.546243 498.279 Guanine nucleotide-binding protein subunit beta-like protein 1 OS=Homo sapiens OX=9606 GN=GNB1L PE=1 SV=2 9.47 2020.6 - 411154 - - - 2.745 - 1.384 0.263 - 104.6 1 2 0 0.0027 10 0 0 0 1.78E+07 3.30E+07 - - - 1.8898 0.9993 221125_WJC_METTL3_EV_vs_WT_F04.08843.08843.2 0.0427 12-Aug K.HAIPIIK.E "sp|O00571|DDX3X_HUMAN,sp|O15523|DDX3Y_HUMAN,tr|A0A2R8YFR4|A0A2R8YFR4_HUMAN,tr|A0A2R8YCW1|A0A2R8YCW1_HUMAN,tr|A0A2R8YDH3|A0A2R8YDH3_HUMAN,tr|A0A2R8YDT5|A0A2R8YDT5_HUMAN,tr|A0A2R8Y645|A0A2R8Y645_HUMAN,tr|A0A2R8YF78|A0A2R8YF78_HUMAN,tr|C9J8G5|C9J8G5_HUMAN,tr|A0A2R8Y4D2|A0A2R8Y4D2_HUMAN,tr|A0A0D9SFB3|A0A0D9SFB3_HUMAN,tr|A0A2R8YFS5|A0A2R8YFS5_HUMAN,tr|A0A0D9SF53|A0A0D9SF53_HUMAN,tr|C9J081|C9J081_HUMAN,tr|A0A2R8Y5G6|A0A2R8Y5G6_HUMAN,tr|A0A2R8Y7T2|A0A2R8Y7T2_HUMAN,tr|A0A0D9SG12|A0A0D9SG12_HUMAN,tr|F6S8Q4|F6S8Q4_HUMAN,tr|A0A2U3TZJ9|A0A2U3TZJ9_HUMAN,tr|A0A2R8Y4A4|A0A2R8Y4A4_HUMAN" 20 790.5065 1.13 43817 8843 2 790.506509 396.2605 ATP-dependent RNA helicase DDX3X OS=Homo sapiens OX=9606 GN=DDX3X PE=1 SV=3 8.76 2021.3 - 3.66E+06 - - - 0 - 1.764 0.256 - 317.7 1 2 0 0 7 0 0 0 1.89E+08 1.67E+08 - - - 2.7302 0.9996 221125_WJC_METTL3_EV_vs_WT_F04.08844.08844.2 0.195 14-Oct K.LTQIIQQK[136.11].D "sp|Q15643|TRIPB_HUMAN,tr|H0YJ97|H0YJ97_HUMAN" 2 978.5953 1.07 43818 8844 2 978.595623 490.3049 Thyroid receptor-interacting protein 11 OS=Homo sapiens OX=9606 GN=TRIP11 PE=1 SV=3 8.75 2021.4 - 1.33E+06 - - - 0.2984 - 2.086 0.271 - 376.3 1 2 0 0.0003 8 0 0 0 3.64E+08 3.41E+08 - - - 3.26 0.9989 221125_WJC_METTL3_EV_vs_WT_F04.08845.08845.2 0.00809 14-Jun R.FDGVQDPR.L sp|O00264|PGRC1_HUMAN 1 932.4352 1.27 43819 8845 2 932.43554 467.2249 Membrane-associated progesterone receptor component 1 OS=Homo sapiens OX=9606 GN=PGRMC1 PE=1 SV=3 4.21 2021.5 - 1.64E+06 - - - 0.37 - 1.44 0.294 - 130.3 1 2 0 0.0003 8 0 0 0 1.28E+08 1.01E+08 - - - 2.3121 0.9999 221125_WJC_METTL3_EV_vs_WT_F04.08847.08847.2 4.21E-06 20-Nov R.LDTGPQSLSGK[136.11].S "sp|P35269|T2FA_HUMAN,tr|M0QXD6|M0QXD6_HUMAN" 2 1109.5808 0.78 43821 8847 2 1109.5804 555.7977 General transcription factor IIF subunit 1 OS=Homo sapiens OX=9606 GN=GTF2F1 PE=1 SV=2 5.84 2021.7 - 739756 - - - -0.3632 - 2.273 0.526 - 381.2 1 2 0 -0.0004 11 0 0 0 2.04E+07 2.61E+07 - - - 5.1472 0.9867 221125_WJC_METTL3_EV_vs_WT_F04.08850.08850.2 0.102 20-Sep R.GLLVDR[166.11]PSETK[136.11].T "sp|Q9UKV3|ACINU_HUMAN,tr|G3V3B0|G3V3B0_HUMAN,tr|S4R3H4|S4R3H4_HUMAN,tr|E7EQT4|E7EQT4_HUMAN" 4 1231.6891 1.31 43824 8850 2 1231.694512 616.8518 Apoptotic chromatin condensation inducer in the nucleus OS=Homo sapiens OX=9606 GN=ACIN1 PE=1 SV=2 6.07 2022.1 - 151805 - - - 4.3761 - 1.889 0.21 - 151.5 1 2 0 0.0054 11 0 0 0 6.80E+06 5.20E+06 - - - 2.311 0.9995 221125_WJC_METTL3_EV_vs_WT_F04.08854.08854.2 0.00254 14-Jun R.FDGVQDPR[166.11].L sp|O00264|PGRC1_HUMAN 1 942.4435 1.27 43826 8854 2 942.443685 472.229 Membrane-associated progesterone receptor component 1 OS=Homo sapiens OX=9606 GN=PGRMC1 PE=1 SV=3 4.21 2022.5 - 1.82E+06 - - - 0.2334 - 1.462 0.387 - 129.8 1 2 0 0.0002 8 0 0 0 1.28E+08 1.01E+08 - - - 3.0448 0.9978 221125_WJC_METTL3_EV_vs_WT_F04.08855.08855.3 0.685 Nov-40 R.GLLVDR[166.11]PSETK[136.11].T "sp|Q9UKV3|ACINU_HUMAN,tr|G3V3B0|G3V3B0_HUMAN,tr|S4R3H4|S4R3H4_HUMAN,tr|E7EQT4|E7EQT4_HUMAN" 4 1231.6891 1.44 43827 8855 3 1231.688897 411.5703 Apoptotic chromatin condensation inducer in the nucleus OS=Homo sapiens OX=9606 GN=ACIN1 PE=1 SV=2 6.07 2022.6 - 955824 - - - -0.1827 - 2.124 0.188 - 125.7 1 2 0 -0.0002 11 0 0 0 6.03E+07 4.20E+07 - - - 2.776 0.9919 221125_WJC_METTL3_EV_vs_WT_F04.08859.08859.2 0.0558 20-Aug R.TVEVAEGEAVR[166.11].T "sp|Q86UE4|LYRIC_HUMAN,tr|H0YB56|H0YB56_HUMAN,tr|E5RJU9|E5RJU9_HUMAN" 3 1168.5963 0.36 43831 8859 2 1168.592598 585.3054 Protein LYRIC OS=Homo sapiens OX=9606 GN=MTDH PE=1 SV=2 4.25 2023.1 - 146347 - - - -3.1996 - 1.606 0.225 - 173.2 1 2 0 -0.0037 11 0 0 0 5.09E+07 1.40E+08 - - - 1.9833 0.9995 221125_WJC_METTL3_EV_vs_WT_F04.08862.08862.2 0.0286 14-Sep K.LTQIIQQK.D "sp|Q15643|TRIPB_HUMAN,tr|H0YJ97|H0YJ97_HUMAN" 2 970.5811 1.07 43832 8862 2 970.580847 486.2978 Thyroid receptor-interacting protein 11 OS=Homo sapiens OX=9606 GN=TRIP11 PE=1 SV=3 8.75 2023.5 - 5.50E+06 - - - -0.2926 - 1.965 0.275 - 273.1 1 2 0 -0.0003 8 0 0 0 3.64E+08 3.41E+08 - - - 3.1093 0.9998 221125_WJC_METTL3_EV_vs_WT_F04.08863.08863.3 0.00903 Dec-40 R.GLLVDRPSETK.T "sp|Q9UKV3|ACINU_HUMAN,tr|G3V3B0|G3V3B0_HUMAN,tr|S4R3H4|S4R3H4_HUMAN,tr|E7EQT4|E7EQT4_HUMAN" 4 1213.6667 1.44 43833 8863 3 1213.665609 405.5628 Apoptotic chromatin condensation inducer in the nucleus OS=Homo sapiens OX=9606 GN=ACIN1 PE=1 SV=2 6.07 2023.6 - 2.10E+06 - - - -0.8594 - 2.213 0.358 - 173.6 1 2 0 -0.001 11 0 0 0 6.02E+07 4.19E+07 - - - 4.7877 0.9999 221125_WJC_METTL3_EV_vs_WT_F04.08864.08864.2 1.87E-06 20-Oct K.EVANSTANLVK.T "sp|Q9Y4G6|TLN2_HUMAN,sp|Q9Y490|TLN1_HUMAN,tr|A0A1B0GVU7|A0A1B0GVU7_HUMAN,tr|H0YMT1|H0YMT1_HUMAN" 4 1144.6088 1.42 43834 8864 2 1144.608198 573.3117 Talin-2 OS=Homo sapiens OX=9606 GN=TLN2 PE=1 SV=4 6.1 2023.7 - 1.23E+06 - - - -0.5277 - 2.006 0.532 - 288.7 1 2 0 -0.0006 11 0 0 0 2.48E+07 1.75E+07 - - - 4.8534 0.992 221125_WJC_METTL3_EV_vs_WT_F04.08865.08865.2 0.203 14-Aug R.NLAENISR[166.11].V "sp|P06737|PYGL_HUMAN,sp|P11217|PYGM_HUMAN,sp|P11216|PYGB_HUMAN,tr|E9PK47|E9PK47_HUMAN" 4 925.4857 0.87 43835 8865 2 925.486415 463.7501 "Glycogen phosphorylase, liver form OS=Homo sapiens OX=9606 GN=PYGL PE=1 SV=4" 6 2023.8 - 481337 - - - 0.8115 - 1.347 0.131 - 232.1 1 2 0 0.0008 8 0 0 0 9.37E+06 1.08E+07 - - - 0.9067 0.9399 221125_WJC_METTL3_EV_vs_WT_F04.08866.08866.2 0.00153 12-Jul T.PTHYLTK[136.11].H "sp|P04844|RPN2_HUMAN,tr|Q5JYR7|Q5JYR7_HUMAN" 2 866.4742 1.16 43836 8866 2 866.474714 434.2444 Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit 2 OS=Homo sapiens OX=9606 GN=RPN2 PE=1 SV=3 9.01 2023.9 - 392734 - - - 0.6475 - 1.555 0.27 - 149.4 1 1 0 0.0006 7 0 0 0 2.00E+07 1.73E+07 - - - 2.4339 0.9969 221125_WJC_METTL3_EV_vs_WT_F04.08869.08869.2 0.0196 16-Oct K.QAYTQFGGK[136.11].R "sp|P25789|PSA4_HUMAN,tr|H0YKS0|H0YKS0_HUMAN,tr|H0YKT8|H0YKT8_HUMAN,tr|H0YMI6|H0YMI6_HUMAN,tr|H0YMV3|H0YMV3_HUMAN,tr|H0YMA1|H0YMA1_HUMAN,tr|H0YLC2|H0YLC2_HUMAN,tr|H0YL69|H0YL69_HUMAN,tr|H0YN18|H0YN18_HUMAN,tr|H0YMZ1|H0YMZ1_HUMAN" 10 1006.4963 1.62 43837 8869 2 1006.493197 504.2554 Proteasome subunit alpha type-4 OS=Homo sapiens OX=9606 GN=PSMA4 PE=1 SV=1 8.59 2024.3 - 1.32E+06 - - - -3.1277 - 1.479 0.353 - 229.7 1 2 0 -0.0031 9 0 0 0 4.48E+07 2.76E+07 - - - 2.7795 0.998 221125_WJC_METTL3_EV_vs_WT_F04.08872.08872.2 0.00216 14-Aug R.STFSTNYR[166.11].S "sp|P05783|K1C18_HUMAN,tr|F8VZY9|F8VZY9_HUMAN" 2 984.454 1.93 43840 8872 2 984.452822 493.2343 "Keratin, type I cytoskeletal 18 OS=Homo sapiens OX=9606 GN=KRT18 PE=1 SV=2" 8.46 2024.6 - 628838 - - - -1.2271 - 1.664 0.198 - 234.1 1 2 0 -0.0012 8 0 0 0 1.49E+08 7.73E+07 - - - 2.0388 0.9992 221125_WJC_METTL3_EV_vs_WT_F04.08877.08877.2 0.00923 18-Sep R.GTQGAEEVLR.A "sp|Q15149|PLEC_HUMAN,tr|H0YDN1|H0YDN1_HUMAN" 2 1058.5356 2.21 43843 8877 2 1058.533115 530.2751 Plectin OS=Homo sapiens OX=9606 GN=PLEC PE=1 SV=3 4.53 2025.2 - 1.55E+06 - - - -2.3825 - 1.778 0.402 - 317.1 1 2 0 -0.0025 10 0 0 0 3.36E+07 1.52E+07 - - - 3.6157 0.9996 221125_WJC_METTL3_EV_vs_WT_F04.08882.08882.2 0.00621 16-Oct K.TAVC[160.03]DIPPR.G "sp|P04350|TBB4A_HUMAN,sp|Q9BVA1|TBB2B_HUMAN,sp|A6NNZ2|TBB8B_HUMAN,sp|P07437|TBB5_HUMAN,sp|Q13885|TBB2A_HUMAN,sp|P68371|TBB4B_HUMAN,sp|Q3ZCM7|TBB8_HUMAN,tr|Q5ST81|Q5ST81_HUMAN,tr|Q5JP53|Q5JP53_HUMAN,tr|A0A075B736|A0A075B736_HUMAN,tr|Q5SQY0|Q5SQY0_HUMAN" 11 1027.5121 0.38 43846 8882 2 1027.513393 514.7633 Tubulin beta-4A chain OS=Homo sapiens OX=9606 GN=TUBB4A PE=1 SV=2 5.5 2025.9 - 483047 - - - 1.2924 - 2.113 0.325 - 501.2 1 2 0 0.0013 9 0 0 0 1.70E+07 4.43E+07 - - - 3.6054 0.9893 221125_WJC_METTL3_EV_vs_WT_F04.08884.08884.2 0.215 14-May K.K[136.11]LLGLGQK[136.11].H "sp|P49321|NASP_HUMAN,tr|E9PI86|E9PI86_HUMAN,tr|Q5T624|Q5T624_HUMAN,tr|E9PPQ8|E9PPQ8_HUMAN" 4 871.5826 0.65 43848 8884 2 871.581027 436.7986 Nuclear autoantigenic sperm protein OS=Homo sapiens OX=9606 GN=NASP PE=1 SV=2 10 2026.1 - 383174 - - - -1.791 - 1.258 0.172 - 83 1 2 0 -0.0016 8 0 0 0 6.76E+06 1.03E+07 - - - 1.0031 0.9916 221125_WJC_METTL3_EV_vs_WT_F04.08888.08888.2 0.219 18-Aug R.AQAQPGVPLR.E "sp|Q9HC84|MUC5B_HUMAN,sp|Q9HC84|MUC5B_HUMAN,sp|Q9HC84|MUC5B_HUMAN" 3 1035.5825 205.81 43850 8888 2 1035.585694 518.7985 Mucin-5B OS=Homo sapiens OX=9606 GN=MUC5B PE=1 SV=3 9.79 2026.7 - 746816 - - - 3.0572 - 1.591 0.21 - 231.1 1 2 0 0.0032 10 0 0 0 4.77E+07 2.32E+05 - - - 1.8872 0.948 221125_WJC_METTL3_EV_vs_WT_F04.08889.08889.2 0.0808 14-Jul L.AHLGVQVK.G "sp|P04843|RPN1_HUMAN,tr|F8WF32|F8WF32_HUMAN" 2 850.5025 1.09 43851 8889 2 850.502772 426.2585 Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit 1 OS=Homo sapiens OX=9606 GN=RPN1 PE=1 SV=1 8.8 2026.7 - 1.60E+06 - - - 0.3351 - 1.427 0.322 - 155.4 1 1 0 0.0003 8 0 0 0 3.27E+07 3.00E+07 - - - 2.4916 0.9977 221125_WJC_METTL3_EV_vs_WT_F04.08895.08895.2 0.0263 18-Oct R.FEEPDSASVK.T "sp|Q8N9T8|KRI1_HUMAN,tr|A0A494C108|A0A494C108_HUMAN" 2 1107.5084 1.07 43855 8895 2 1107.505017 554.7615 Protein KRI1 homolog OS=Homo sapiens OX=9606 GN=KRI1 PE=1 SV=3 4.14 2027.4 - 798273 - - - -3.0727 - 1.674 0.35 - 288.2 1 2 0 -0.0034 10 0 0 0 2.15E+07 2.01E+07 - - - 3.0632 0.9965 221125_WJC_METTL3_EV_vs_WT_F04.08896.08896.2 0.0184 18-Oct R.TVAVITSDGR[166.11].M "sp|O95777|LSM8_HUMAN,tr|C9JNV3|C9JNV3_HUMAN,tr|F2Z2Y6|F2Z2Y6_HUMAN" 3 1027.5537 2.92 43856 8896 2 1027.557134 514.7841 U6 snRNA-associated Sm-like protein LSm8 OS=Homo sapiens OX=9606 GN=LSM8 PE=1 SV=3 5.5 2027.5 - 839559 - - - 3.2991 - 1.867 0.276 - 343.8 1 2 0 0.0034 10 0 0 0 2.65E+08 9.06E+07 - - - 2.8212 0.9544 221125_WJC_METTL3_EV_vs_WT_F04.08897.08897.2 4.07 14-Aug R.RILQSLEK.M sp|P49790|NU153_HUMAN 1 985.592 1.23 43857 8897 2 985.591372 493.8033 Nuclear pore complex protein Nup153 OS=Homo sapiens OX=9606 GN=NUP153 PE=1 SV=2 8.75 2027.6 - 3.04E+06 - - - -0.6676 - 1.064 0.059 - 150.3 1 2 0 -0.0007 8 0 0 0 4.64E+07 3.76E+07 - - - -0.3363 0.9312 221125_WJC_METTL3_EV_vs_WT_F04.08898.08898.2 1.27E-05 28-Oct R.SDSPVPTAPTSGGPK[136.11].P "sp|Q86U44|MTA70_HUMAN,tr|B4E349|B4E349_HUMAN,tr|F5H6D8|F5H6D8_HUMAN,tr|B4DTN4|B4DTN4_HUMAN" 4 1404.6976 0.01 43858 8898 2 1404.691439 703.3561 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 5.55 2027.7 - 234773 - - - -4.4031 - 2.025 0.608 - 220 1 1 0 -0.0062 15 0 0 0 1.20E+05 1.14E+07 - - - 5.2644 0.9989 221125_WJC_METTL3_EV_vs_WT_F04.08902.08902.2 0.00138 14-Jun R.DYEEMASR[166.11].L "sp|P29590|PML_HUMAN,tr|H3BUJ5|H3BUJ5_HUMAN,tr|H3BT29|H3BT29_HUMAN,tr|H3BT57|H3BT57_HUMAN" 4 1009.405 0.87 43860 8902 2 1009.402604 505.7098 Protein PML OS=Homo sapiens OX=9606 GN=PML PE=1 SV=3 4.14 2028.2 - 473817 - - - -2.4044 - 1.218 0.491 - 102.5 1 2 0 -0.0024 8 0 0 0 1.19E+07 1.36E+07 - - - 3.2615 0.9981 221125_WJC_METTL3_EV_vs_WT_F04.08917.08917.2 0.0397 20-Sep R.NTTGVTEEALK.E "sp|Q13813|SPTN1_HUMAN,tr|A0A0D9SF54|A0A0D9SF54_HUMAN,tr|A0A0D9SGF6|A0A0D9SGF6_HUMAN" 3 1161.5877 0.54 43868 8917 2 1161.585434 581.8011 "Spectrin alpha chain, non-erythrocytic 1 OS=Homo sapiens OX=9606 GN=SPTAN1 PE=1 SV=3" 4.53 2030.1 - 1.70E+06 - - - -1.9792 - 1.716 0.265 - 305.2 1 2 0 -0.0023 11 0 0 0 4.64E+07 8.61E+07 - - - 2.4584 0.9908 221125_WJC_METTL3_EV_vs_WT_F04.08918.08918.3 0.0295 Dec-40 R.LTSAIKPEIAK.M "sp|O15063|GRRE1_HUMAN,tr|A0A0G2JQ84|A0A0G2JQ84_HUMAN,tr|U3KPV0|U3KPV0_HUMAN,tr|A0A0G2JQ76|A0A0G2JQ76_HUMAN" 4 1169.702 8.15 43869 8918 3 1169.704818 390.9079 Granule associated Rac and RHOG effector protein 1 OS=Homo sapiens OX=9606 GN=GARRE1 PE=1 SV=2 8.59 2030.2 - 350047 - - - 2.4314 - 2.021 0.171 - 122.5 1 2 0 0.0028 11 0 0 0 7.37E+06 9.04E+05 - - - 2.4445 0.7725 221125_WJC_METTL3_EV_vs_WT_F04.08919.08919.2 0.982 16-Jun R.AYDLAGSC[160.03]R.G "sp|Q02880|TOP2B_HUMAN,tr|E9PCY5|E9PCY5_HUMAN" 2 1011.4444 1.38 43870 8919 2 1011.449064 506.7295 DNA topoisomerase 2-beta OS=Homo sapiens OX=9606 GN=TOP2B PE=1 SV=3 5.87 2030.3 - 622718 - - - 4.631 - 1.134 0.125 - 70.6 2 2 0 0.0047 9 0 0 0 1.38E+07 1.00E+07 - - - 0.1921 0.9946 221125_WJC_METTL3_EV_vs_WT_F04.08920.08920.3 0.0555 28-Jul K.LWC[160.03]TYHEK[136.11].G "sp|P15121|ALDR_HUMAN,tr|E9PCX2|E9PCX2_HUMAN" 2 1143.5263 0.02 43871 8920 3 1143.525849 382.1827 Aldo-keto reductase family 1 member B1 OS=Homo sapiens OX=9606 GN=AKR1B1 PE=1 SV=3 6.74 2030.4 - 478980 - - - -0.3638 - 1.334 0.246 - 52.4 1 2 0 -0.0004 8 0 0 0 1.54E+05 8.14E+06 - - - 2.1833 0.9998 221125_WJC_METTL3_EV_vs_WT_F04.08921.08921.2 2.34E-05 22-Nov R.VIGSGC[160.03]NLDSAR[166.11].F "sp|Q6ZMR3|LDH6A_HUMAN,sp|P00338|LDHA_HUMAN,sp|P07195|LDHB_HUMAN,sp|P07864|LDHC_HUMAN,tr|A0A087WUM2|A0A087WUM2_HUMAN,tr|A8MW50|A8MW50_HUMAN,tr|G3XAP5|G3XAP5_HUMAN,tr|F5H155|F5H155_HUMAN,tr|F5H245|F5H245_HUMAN,tr|F5H5G7|F5H5G7_HUMAN,tr|A0A3B3IS95|A0A3B3IS95_HUMAN,tr|A0A5F9ZHM4|A0A5F9ZHM4_HUMAN" 12 1257.6011 1.06 43872 8921 2 1257.602314 629.8078 L-lactate dehydrogenase A-like 6A OS=Homo sapiens OX=9606 GN=LDHAL6A PE=2 SV=1 5.8 2030.6 - 260846 - - - 0.9614 - 2.076 0.532 - 178.4 1 2 0 0.0012 12 0 0 0 1.12E+08 1.06E+08 - - - 4.8919 0.9999 221125_WJC_METTL3_EV_vs_WT_F04.08930.08930.2 3.02E-07 13/22 R.VIGSGC[160.03]NLDSAR.F "sp|Q6ZMR3|LDH6A_HUMAN,sp|P00338|LDHA_HUMAN,sp|P07195|LDHB_HUMAN,sp|P07864|LDHC_HUMAN,tr|A0A087WUM2|A0A087WUM2_HUMAN,tr|A8MW50|A8MW50_HUMAN,tr|G3XAP5|G3XAP5_HUMAN,tr|F5H155|F5H155_HUMAN,tr|F5H245|F5H245_HUMAN,tr|F5H5G7|F5H5G7_HUMAN,tr|A0A3B3IS95|A0A3B3IS95_HUMAN,tr|A0A5F9ZHM4|A0A5F9ZHM4_HUMAN" 12 1247.5928 1.04 43879 8930 2 1247.592858 624.8037 L-lactate dehydrogenase A-like 6A OS=Homo sapiens OX=9606 GN=LDHAL6A PE=2 SV=1 5.8 2031.5 - 453415 - - - 0.0184 - 2.19 0.592 - 508 1 2 0 0 12 0 0 0 1.13E+08 1.08E+08 - - - 5.4761 0.996 221125_WJC_METTL3_EV_vs_WT_F04.08933.08933.2 0.693 12-Jun R.INIPPQR.G "sp|Q13283|G3BP1_HUMAN,tr|A0A7I2V5M7|A0A7I2V5M7_HUMAN,tr|A0A7P0P2U7|A0A7P0P2U7_HUMAN,tr|A0A7I2YQU8|A0A7I2YQU8_HUMAN,tr|A0A7I2V548|A0A7I2V548_HUMAN,tr|A0A7I2V565|A0A7I2V565_HUMAN,tr|A0A7I2YQN9|A0A7I2YQN9_HUMAN" 7 836.4868 0.57 43881 8933 2 836.487537 419.2507 Ras GTPase-activating protein-binding protein 1 OS=Homo sapiens OX=9606 GN=G3BP1 PE=1 SV=1 9.75 2031.8 - 746802 - - - 0.8368 - 1.405 0.177 - 172 1 2 0 0.0007 7 0 0 0 3.57E+07 6.25E+07 - - - 1.4255 0.9992 221125_WJC_METTL3_EV_vs_WT_F04.08935.08935.2 0.00528 14-Aug K.SDPVVSYR[166.11].E sp|P13639|EF2_HUMAN 1 931.4639 0.72 43882 8935 2 931.464778 466.7392 Elongation factor 2 OS=Homo sapiens OX=9606 GN=EEF2 PE=1 SV=4 5.55 2032.1 - 3.70E+06 - - - 0.9791 - 1.379 0.376 - 305.4 1 2 0 0.0009 8 0 0 0 1.08E+08 1.50E+08 - - - 2.7871 0.9264 221125_WJC_METTL3_EV_vs_WT_F04.08937.08937.2 5.8 12-May K.EVSTYIK[136.11].K "sp|P68104|EF1A1_HUMAN,sp|Q5VTE0|EF1A3_HUMAN,tr|A0A7I2V659|A0A7I2V659_HUMAN,tr|A0A7I2V3H3|A0A7I2V3H3_HUMAN,tr|A0A7I2V5N4|A0A7I2V5N4_HUMAN,tr|A0A087WVQ9|A0A087WVQ9_HUMAN,tr|A0A087WV01|A0A087WV01_HUMAN" 7 846.4578 0.45 43884 8937 2 846.458342 424.2362 Elongation factor 1-alpha 1 OS=Homo sapiens OX=9606 GN=EEF1A1 PE=1 SV=1 6.1 2032.2 - 1.78E+06 - - - 0.6001 - 1.085 0.04 - 121.4 3 2 0 0.0005 7 0 0 0 2.22E+07 4.87E+07 - - - -0.6184 0.999 221125_WJC_METTL3_EV_vs_WT_F04.08938.08938.3 0.00921 14/36 R.AMLDAHPEVR[166.11].C "sp|O60704|TPST2_HUMAN,tr|B1AHJ7|B1AHJ7_HUMAN,tr|B1AHJ6|B1AHJ6_HUMAN" 3 1147.5683 1.21 43885 8938 3 1147.568961 383.5301 Protein-tyrosine sulfotransferase 2 OS=Homo sapiens OX=9606 GN=TPST2 PE=1 SV=1 5.32 2032.3 - 383196 - - - 0.5342 - 1.722 0.285 - 262.6 1 2 0 0.0006 10 0 0 0 7.50E+06 6.18E+06 - - - 3.3045 0.9999 221125_WJC_METTL3_EV_vs_WT_F04.08939.08939.3 0.000156 13/36 R.AMLDAHPEVR.C "sp|O60704|TPST2_HUMAN,tr|B1AHJ7|B1AHJ7_HUMAN,tr|B1AHJ6|B1AHJ6_HUMAN" 3 1137.5601 1.02 43886 8939 3 1137.560893 380.194 Protein-tyrosine sulfotransferase 2 OS=Homo sapiens OX=9606 GN=TPST2 PE=1 SV=1 5.32 2032.5 - 308003 - - - 0.7164 - 2.659 0.387 - 258.2 1 2 0 0.0008 10 0 0 0 6.18E+06 6.06E+06 - - - 5.7105 0.9998 221125_WJC_METTL3_EV_vs_WT_F04.08941.08941.2 0.0296 18-Nov R.TGYGGGFNER.E sp|O95218|ZRAB2_HUMAN 1 1056.4625 0.02 43887 8941 2 1056.463957 529.2385 Zinc finger Ran-binding domain-containing protein 2 OS=Homo sapiens OX=9606 GN=ZRANB2 PE=1 SV=2 5.66 2032.7 - 1.19E+06 - - - 1.4056 - 1.878 0.558 - 277.4 1 2 0 0.0015 10 0 0 0 2.03E+07 8.59E+08 - - - 4.921 0.999 221125_WJC_METTL3_EV_vs_WT_F04.08943.08943.2 0.0695 14-Aug K.EANEILQR[166.11].S "sp|P12268|IMDH2_HUMAN,sp|P20839|IMDH1_HUMAN,tr|A0A7I2YQK5|A0A7I2YQK5_HUMAN,tr|C9J381|C9J381_HUMAN,tr|H0Y4R1|H0Y4R1_HUMAN,tr|C9K0R9|C9K0R9_HUMAN,tr|A0A7I2V2T3|A0A7I2V2T3_HUMAN,tr|E7ETK5|E7ETK5_HUMAN,tr|A0A3B3IRL5|A0A3B3IRL5_HUMAN" 9 981.5119 0.98 43888 8943 2 981.512995 491.7632 Inosine-5'-monophosphate dehydrogenase 2 OS=Homo sapiens OX=9606 GN=IMPDH2 PE=1 SV=2 4.53 2032.9 - 3.84E+06 - - - 1.137 - 1.614 0.292 - 352.1 1 2 0 0.0011 8 0 0 0 1.52E+08 1.55E+08 - - - 2.6411 0.9987 221125_WJC_METTL3_EV_vs_WT_F04.08944.08944.3 0.413 Oct-36 K.IFEEHGDLTK.L sp|Q8IW75|SPA12_HUMAN 1 1187.5823 88.54 43889 8944 3 1187.582721 396.868 Serpin A12 OS=Homo sapiens OX=9606 GN=SERPINA12 PE=1 SV=1 4.65 2033 - 1.64E+06 - - - 0.3941 - 1.745 0.267 - 73.3 1 2 0 0.0005 10 0 0 0 3.17E+07 3.58E+05 - - - 3.1426 0.9998 221125_WJC_METTL3_EV_vs_WT_F04.08945.08945.2 5.43E-06 20-Aug R.LATNTSAPDLK[136.11].N "sp|P27816|MAP4_HUMAN,tr|H0Y2V1|H0Y2V1_HUMAN,tr|E7EVA0|E7EVA0_HUMAN,tr|F8W9U4|F8W9U4_HUMAN,tr|H7C4C5|H7C4C5_HUMAN,tr|A0A804HKE7|A0A804HKE7_HUMAN,tr|B5MEG9|B5MEG9_HUMAN" 7 1137.6121 0.42 43890 8945 2 1137.612681 569.8133 Microtubule-associated protein 4 OS=Homo sapiens OX=9606 GN=MAP4 PE=1 SV=3 5.84 2033 - 2.12E+06 - - - 0.5081 - 2.066 0.464 - 220.3 1 2 0 0.0006 11 0 0 0 2.07E+07 4.94E+07 - - - 4.4309 0.9809 221125_WJC_METTL3_EV_vs_WT_F04.08950.08950.2 0.638 14-Jul R.VLLGETGK[136.11].E "sp|P62280|RS11_HUMAN,tr|M0QZC5|M0QZC5_HUMAN,tr|M0R1H6|M0R1H6_HUMAN" 3 823.4895 0.99 43893 8950 2 823.492131 412.752 40S ribosomal protein S11 OS=Homo sapiens OX=9606 GN=RPS11 PE=1 SV=3 5.97 2033.7 - 316161 - - - 3.2326 - 1.349 0.19 - 142.3 1 2 0 0.0027 8 0 0 0 5.91E+06 5.99E+06 - - - 1.3464 0.965 221125_WJC_METTL3_EV_vs_WT_F04.08953.08953.2 8.73E-06 26-Oct S.LVSGLNSSASEPAK[136.11].E "sp|Q86U44|MTA70_HUMAN,tr|F5H6D8|F5H6D8_HUMAN,tr|H0YFV6|H0YFV6_HUMAN,tr|B4DTN4|B4DTN4_HUMAN" 4 1366.7184 0.13 43896 8953 2 1366.721973 684.3665 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 6 2034 - 269289 - - - 2.6443 - 1.914 0.494 - 222.2 1 1 0 0.0036 14 0 0 0 1.12E+06 8.91E+06 - - - 4.3177 0.9997 221125_WJC_METTL3_EV_vs_WT_F04.08957.08957.2 0.000844 18-Oct K.ITSEIPQTER[166.11].M "sp|P82979|SARNP_HUMAN,tr|F8VZQ9|F8VZQ9_HUMAN,tr|H0YHG0|H0YHG0_HUMAN" 3 1182.612 0.85 43898 8957 2 1182.612709 592.3133 SAP domain-containing ribonucleoprotein OS=Homo sapiens OX=9606 GN=SARNP PE=1 SV=3 4.53 2034.5 - 1.97E+06 - - - 0.6105 - 2.018 0.382 - 332.6 1 2 0 0.0007 10 0 0 0 8.55E+07 1.01E+08 - - - 3.822 0.9991 221125_WJC_METTL3_EV_vs_WT_F04.08959.08959.2 0.00201 14-Jul K.SDPVVSYR.E sp|P13639|EF2_HUMAN 1 921.4556 0.72 43899 8959 2 921.455815 461.7351 Elongation factor 2 OS=Homo sapiens OX=9606 GN=EEF2 PE=1 SV=4 5.55 2034.7 - 3.09E+06 - - - 0.2377 - 1.287 0.362 - 237.4 1 2 0 0.0002 8 0 0 0 1.08E+08 1.50E+08 - - - 2.4756 0.9999 221125_WJC_METTL3_EV_vs_WT_F04.08960.08960.3 1.56E-05 14/44 R.TLVAVKPDGVQR.R "sp|O00746|NDKM_HUMAN,tr|Q4TT34|Q4TT34_HUMAN,tr|A0A087WVT9|A0A087WVT9_HUMAN,tr|H0Y6J0|H0Y6J0_HUMAN,tr|F2Z2X0|F2Z2X0_HUMAN" 5 1281.7405 1.5 43900 8960 3 1281.742067 428.2541 "Nucleoside diphosphate kinase, mitochondrial OS=Homo sapiens OX=9606 GN=NME4 PE=1 SV=1" 8.41 2034.8 - 1.48E+06 - - - 1.2343 - 2.247 0.411 - 211.5 1 2 0 0.0016 12 0 0 0 7.03E+07 4.70E+07 - - - 5.3659 0.9991 221125_WJC_METTL3_EV_vs_WT_F04.08966.08966.2 0.000281 22-Oct R.TLVAVKPDGVQR.R "sp|O00746|NDKM_HUMAN,tr|Q4TT34|Q4TT34_HUMAN,tr|A0A087WVT9|A0A087WVT9_HUMAN,tr|H0Y6J0|H0Y6J0_HUMAN,tr|F2Z2X0|F2Z2X0_HUMAN" 5 1281.7405 3.34 43906 8966 2 1281.744051 641.8775 "Nucleoside diphosphate kinase, mitochondrial OS=Homo sapiens OX=9606 GN=NME4 PE=1 SV=1" 8.41 2035.4 - 109979 - - - 2.7822 - 2.194 0.378 - 318.6 1 2 0 0.0036 12 0 0 0 5.53E+06 1.66E+06 - - - 3.8992 0.9998 221125_WJC_METTL3_EV_vs_WT_F04.08970.08970.3 0.00398 14/44 R.TLVAVK[136.11]PDGVQR[166.11].R "sp|O00746|NDKM_HUMAN,tr|Q4TT34|Q4TT34_HUMAN,tr|A0A087WVT9|A0A087WVT9_HUMAN,tr|H0Y6J0|H0Y6J0_HUMAN,tr|F2Z2X0|F2Z2X0_HUMAN" 5 1299.763 1.49 43908 8970 3 1299.763087 434.2616 "Nucleoside diphosphate kinase, mitochondrial OS=Homo sapiens OX=9606 GN=NME4 PE=1 SV=1" 8.41 2035.9 - 1.48E+06 - - - 0.1016 - 2.04 0.369 - 224.6 1 2 0 0.0001 12 0 0 0 7.07E+07 4.73E+07 - - - 4.6301 0.9936 221125_WJC_METTL3_EV_vs_WT_F04.08972.08972.2 0.375 18-May R.VPITPENPC[160.03]K.E sp|Q5W0B1|OBI1_HUMAN 1 1153.5801 0.31 43910 8972 2 1153.581481 577.7973 ORC ubiquitin ligase 1 OS=Homo sapiens OX=9606 GN=OBI1 PE=1 SV=1 5.97 2036.1 - 166578 - - - 1.1581 - 1.118 0.247 - 51.3 1 2 0 0.0013 10 0 0 0 1.18E+07 3.83E+07 - - - 1.1763 0.9996 221125_WJC_METTL3_EV_vs_WT_F04.08977.08977.2 0.00896 18-Oct K.VAIESAVQQK[136.11].Q "sp|Q68CP9|ARID2_HUMAN,tr|F8VWP4|F8VWP4_HUMAN,tr|F8W108|F8W108_HUMAN,tr|F8WCU9|F8WCU9_HUMAN" 4 1079.6066 0.97 43913 8977 2 1079.606288 540.8106 AT-rich interactive domain-containing protein 2 OS=Homo sapiens OX=9606 GN=ARID2 PE=1 SV=2 5.97 2036.8 - 597011 - - - -0.3112 - 2.218 0.286 - 304.2 1 2 0 -0.0003 10 0 0 0 5.46E+07 5.63E+07 - - - 3.3769 0.9997 221125_WJC_METTL3_EV_vs_WT_F04.08982.08982.2 3.10E-05 22-Nov R.QPLGATSGASLK.T sp|Q9HCD5|NCOA5_HUMAN 1 1128.6139 1.73 43916 8982 2 1128.613973 565.3142 Nuclear receptor coactivator 5 OS=Homo sapiens OX=9606 GN=NCOA5 PE=1 SV=2 8.75 2037.3 - 6.74E+06 - - - 0.0753 - 1.919 0.411 - 385.2 1 2 0 0.0001 12 0 0 0 2.82E+08 1.63E+08 - - - 3.7916 0.9998 221125_WJC_METTL3_EV_vs_WT_F04.08985.08985.2 2.84E-06 18-Oct R.AFEEDQVAGR.L sp|O43818|U3IP2_HUMAN 1 1120.5149 9.66 43919 8985 2 1120.513004 561.2647 U3 small nucleolar RNA-interacting protein 2 OS=Homo sapiens OX=9606 GN=RRP9 PE=1 SV=1 4.14 2037.5 - 2.21E+06 - - - -1.6939 - 1.9 0.526 - 412 1 2 0 -0.0019 10 0 0 0 6.04E+07 6.26E+06 - - - 4.717 0.9999 221125_WJC_METTL3_EV_vs_WT_F04.08986.08986.3 0.0154 15/36 K.ILAHNNFVGR[166.11].L "sp|Q9NZI8|IF2B1_HUMAN,sp|O00425|IF2B3_HUMAN" 2 1149.6282 1.35 43920 8986 3 1149.627768 384.2167 Insulin-like growth factor 2 mRNA-binding protein 1 OS=Homo sapiens OX=9606 GN=IGF2BP1 PE=1 SV=2 9.76 2037.6 - 1.95E+06 - - - -0.4158 - 2.381 0.365 - 269.7 1 2 0 -0.0005 10 0 0 0 7.99E+08 5.91E+08 - - - 5.1428 0.9991 221125_WJC_METTL3_EV_vs_WT_F04.08987.08987.2 0.0289 16-Jul K.AWENSPNVR.E "sp|Q9Y520|PRC2C_HUMAN,tr|E7EPN9|E7EPN9_HUMAN,tr|H7C5N8|H7C5N8_HUMAN,tr|A0A2R8Y7F4|A0A2R8Y7F4_HUMAN,tr|A0A2R8YET2|A0A2R8YET2_HUMAN" 5 1071.5098 4.2 43921 8987 2 1071.510565 536.7622 Protein PRRC2C OS=Homo sapiens OX=9606 GN=PRRC2C PE=1 SV=4 6.05 2037.7 - 1.07E+06 - - - 0.7541 - 1.623 0.296 - 208 1 2 0 0.0008 9 0 0 0 4.29E+07 1.02E+07 - - - 2.628 0.9591 221125_WJC_METTL3_EV_vs_WT_F04.08988.08988.2 0.0923 16-Aug R.INQLYEQAK[136.11].W "sp|Q96AC1|FERM2_HUMAN,tr|H0YJ34|H0YJ34_HUMAN,tr|A0A0U1RRM8|A0A0U1RRM8_HUMAN" 3 1113.591 0.61 43922 8988 2 1113.58511 557.8028 Fermitin family homolog 2 OS=Homo sapiens OX=9606 GN=FERMT2 PE=1 SV=1 6 2037.8 - 748978 - - - -5.2658 - 1.479 0.229 - 191 1 2 0 -0.0059 9 0 0 0 4.73E+06 7.73E+06 - - - 1.8628 0.9981 221125_WJC_METTL3_EV_vs_WT_F04.08989.08989.2 0.0817 16-Jul K.AWENSPNVR[166.11].E "sp|Q9Y520|PRC2C_HUMAN,tr|E7EPN9|E7EPN9_HUMAN,tr|H7C5N8|H7C5N8_HUMAN,tr|A0A2R8Y7F4|A0A2R8Y7F4_HUMAN,tr|A0A2R8YET2|A0A2R8YET2_HUMAN" 5 1081.518 4.23 43923 8989 2 1081.519658 541.7663 Protein PRRC2C OS=Homo sapiens OX=9606 GN=PRRC2C PE=1 SV=4 6.05 2037.8 - 522565 - - - 1.5081 - 1.45 0.291 - 198.3 1 2 0 0.0016 9 0 0 0 4.29E+07 1.01E+07 - - - 2.2648 0.9997 221125_WJC_METTL3_EV_vs_WT_F04.08991.08991.2 0.000114 18-Sep R.LDGSMSYSER[166.11].E "sp|Q9NRZ9|HELLS_HUMAN,tr|Q9NW36|Q9NW36_HUMAN,tr|A0A087WSW7|A0A087WSW7_HUMAN,tr|A0A0B4J1V9|A0A0B4J1V9_HUMAN,tr|F6XU50|F6XU50_HUMAN" 5 1153.4949 0.4 43925 8991 2 1153.496567 577.7547 Lymphoid-specific helicase OS=Homo sapiens OX=9606 GN=HELLS PE=1 SV=1 4.37 2038.1 - 218411 - - - 1.4382 - 1.802 0.497 - 208.1 1 2 0 0.0017 10 0 0 0 2.54E+06 6.33E+06 - - - 4.3551 0.9993 221125_WJC_METTL3_EV_vs_WT_F04.08994.08994.2 0.0663 18-Oct K.ITSEIPQTER.M "sp|P82979|SARNP_HUMAN,tr|F8VZQ9|F8VZQ9_HUMAN,tr|H0YHG0|H0YHG0_HUMAN" 3 1172.6037 0.83 43926 8994 2 1172.602299 587.3091 SAP domain-containing ribonucleoprotein OS=Homo sapiens OX=9606 GN=SARNP PE=1 SV=3 4.53 2038.5 - 3.44E+06 - - - -1.2093 - 1.842 0.308 - 233.9 1 2 0 -0.0014 10 0 0 0 8.38E+07 1.01E+08 - - - 3.0205 0.9586 221125_WJC_METTL3_EV_vs_WT_F04.08995.08995.2 0.00647 12-Aug T.MQNLNDR.L "sp|Q04695|K1C17_HUMAN,sp|Q99456|K1C12_HUMAN,sp|P13645|K1C10_HUMAN,sp|Q2M2I5|K1C24_HUMAN,sp|Q7Z3Z0|K1C25_HUMAN,sp|Q7Z3Y9|K1C26_HUMAN,sp|P02533|K1C14_HUMAN,sp|Q7Z3Y8|K1C27_HUMAN,sp|P08727|K1C19_HUMAN,sp|P35900|K1C20_HUMAN,sp|Q9C075|K1C23_HUMAN,sp|P08779|K1C16_HUMAN,sp|Q7Z3Y7|K1C28_HUMAN,sp|P19012|K1C15_HUMAN,sp|P13646|K1C13_HUMAN,tr|J3QR55|J3QR55_HUMAN,tr|K7EPJ9|K7EPJ9_HUMAN,tr|C9JM50|C9JM50_HUMAN,tr|A0A1B0GVI3|A0A1B0GVI3_HUMAN,tr|K7EMD9|K7EMD9_HUMAN,tr|K7ERE3|K7ERE3_HUMAN,tr|A0A3B3ITG2|A0A3B3ITG2_HUMAN,tr|K7EQH6|K7EQH6_HUMAN" 23 889.4076 102.28 43927 8995 2 889.405938 445.7111 "Keratin, type I cytoskeletal 17 OS=Homo sapiens OX=9606 GN=KRT17 PE=1 SV=2" 5.59 2038.6 - 917323 - - - -1.8687 - 1.533 0.401 - 261.2 1 1 0 -0.0017 7 0 0 0 4.40E+07 4.30E+05 - - - 3.356 0.9998 221125_WJC_METTL3_EV_vs_WT_F04.08996.08996.3 0.00222 Aug-36 K.ILAHNNFVGR.L "sp|Q9NZI8|IF2B1_HUMAN,sp|O00425|IF2B3_HUMAN" 2 1139.62 1.34 43928 8996 3 1139.618615 380.8806 Insulin-like growth factor 2 mRNA-binding protein 1 OS=Homo sapiens OX=9606 GN=IGF2BP1 PE=1 SV=2 9.76 2038.6 - 4.77E+06 - - - -1.1943 - 1.91 0.399 - 69.8 1 2 0 -0.0014 10 0 0 0 8.06E+08 6.02E+08 - - - 4.8779 1 221125_WJC_METTL3_EV_vs_WT_F04.08997.08997.2 5.66E-08 15/22 R.SDAGLESDTAMK[136.11].K sp|Q9NR30|DDX21_HUMAN 1 1231.5482 1.46 43929 8997 2 1231.546831 616.7814 Nucleolar RNA helicase 2 OS=Homo sapiens OX=9606 GN=DDX21 PE=1 SV=5 4.03 2038.8 - 1.25E+06 - - - -1.097 - 3.15 0.694 - 975.5 1 2 0 -0.0014 12 0 0 0 3.32E+07 2.26E+07 - - - 7.1855 0.8702 221125_WJC_METTL3_EV_vs_WT_F04.08999.08999.2 0.159 14-Jun L.YGLGGSKR.L "sp|P48668|K2C6C_HUMAN,sp|P04259|K2C6B_HUMAN,sp|P02538|K2C6A_HUMAN" 3 836.4505 999 43931 8999 2 836.449471 419.2325 "Keratin, type II cytoskeletal 6C OS=Homo sapiens OX=9606 GN=KRT6C PE=1 SV=3" 9.99 2038.9 - 671752 - - - -1.1716 - 1.269 0.28 - 121.2 1 1 0 -0.001 8 0 0 0 1.30E+07 0.00E+00 - - - 1.8273 0.9814 221125_WJC_METTL3_EV_vs_WT_F04.09004.09004.2 0.426 16-Sep K.IK[136.11]EIAVTVK[136.11].K sp|Q99832|TCPH_HUMAN 1 1015.6612 0.14 43934 9004 2 1015.660238 508.8379 T-complex protein 1 subunit eta OS=Homo sapiens OX=9606 GN=CCT7 PE=1 SV=2 8.59 2039.5 - 2.16E+06 - - - -0.9787 - 1.803 0.179 - 194.3 1 2 1 -0.001 9 0 0 0 1.59E+07 1.10E+08 - - - 2.0681 0.9654 221125_WJC_METTL3_EV_vs_WT_F04.09005.09005.2 0.00323 16-Jul R.SSDIVSSVR[166.11].R "sp|Q14C86|GAPD1_HUMAN,tr|F8W9S7|F8W9S7_HUMAN,tr|C9IZ08|C9IZ08_HUMAN,tr|H0Y7I9|H0Y7I9_HUMAN,tr|H0Y4E7|H0Y4E7_HUMAN" 5 958.4959 0.28 43935 9005 2 958.499365 480.2552 GTPase-activating protein and VPS9 domain-containing protein 1 OS=Homo sapiens OX=9606 GN=GAPVD1 PE=1 SV=2 5.55 2039.7 - 474754 - - - 3.6213 - 1.665 0.099 - 142.9 2 2 0 0.0035 9 0 0 0 2.64E+06 9.29E+06 - - - 1.1116 0.9994 221125_WJC_METTL3_EV_vs_WT_F04.09010.09010.2 0.0054 14-Aug K.EANEILQR.S "sp|P12268|IMDH2_HUMAN,sp|P20839|IMDH1_HUMAN,tr|A0A7I2YQK5|A0A7I2YQK5_HUMAN,tr|C9J381|C9J381_HUMAN,tr|H0Y4R1|H0Y4R1_HUMAN,tr|C9K0R9|C9K0R9_HUMAN,tr|A0A7I2V2T3|A0A7I2V2T3_HUMAN,tr|E7ETK5|E7ETK5_HUMAN,tr|A0A3B3IRL5|A0A3B3IRL5_HUMAN" 9 971.5036 0.99 43939 9010 2 971.503058 486.7591 Inosine-5'-monophosphate dehydrogenase 2 OS=Homo sapiens OX=9606 GN=IMPDH2 PE=1 SV=2 4.53 2040.3 - 3.59E+06 - - - -0.5672 - 1.767 0.279 - 376.6 1 2 0 -0.0006 8 0 0 0 1.54E+08 1.55E+08 - - - 2.8185 0.9938 221125_WJC_METTL3_EV_vs_WT_F04.09012.09012.3 0.126 Nov-36 K.ILQQIPDHPK.H sp|Q08554|DSC1_HUMAN 1 1187.6663 312.39 43940 9012 3 1187.665605 396.896 Desmocollin-1 OS=Homo sapiens OX=9606 GN=DSC1 PE=1 SV=2 6.74 2040.5 - 505913 - - - -0.5498 - 1.629 0.191 - 117.4 1 2 0 -0.0007 10 0 0 0 3.87E+07 1.24E+05 - - - 2.0944 0.9992 221125_WJC_METTL3_EV_vs_WT_F04.09014.09014.2 0.118 16-Jul R.EQLDMAGAR[166.11].V "sp|Q14203|DCTN1_HUMAN,tr|A0A804CDA6|A0A804CDA6_HUMAN,tr|E7EX90|E7EX90_HUMAN,tr|A0A7P0Z4C3|A0A7P0Z4C3_HUMAN,tr|Q6AWB1|Q6AWB1_HUMAN" 5 999.4683 6.97 43941 9014 2 999.468683 500.7414 Dynactin subunit 1 OS=Homo sapiens OX=9606 GN=DCTN1 PE=1 SV=3 4.37 2040.8 - 1.35E+06 - - - 0.3842 - 1.442 0.348 - 217.3 1 2 0 0.0004 9 0 0 0 1.49E+08 2.14E+07 - - - 2.6702 0.7903 221125_WJC_METTL3_EV_vs_WT_F04.09015.09015.2 0.2 18-Sep R.TVAVITSDGR.M "sp|O95777|LSM8_HUMAN,tr|C9JNV3|C9JNV3_HUMAN,tr|F2Z2Y6|F2Z2Y6_HUMAN" 3 1017.5455 2.94 43942 9015 2 1018.549282 509.78 U6 snRNA-associated Sm-like protein LSm8 OS=Homo sapiens OX=9606 GN=LSM8 PE=1 SV=3 5.5 2040.8 - 2.03E+06 - - - 986.4994 - 1.526 0.145 - 210 1 2 0 1.0038 10 0 0 0 2.66E+08 9.06E+07 - - - 0.9765 0.9994 221125_WJC_METTL3_EV_vs_WT_F04.09016.09016.2 0.00254 22-Sep R.AGGPATPLSPTR.L sp|Q03252|LMNB2_HUMAN 1 1123.5986 1.29 43943 9016 2 1123.598135 562.8066 Lamin-B2 OS=Homo sapiens OX=9606 GN=LMNB2 PE=1 SV=4 9.79 2040.9 - 1.58E+06 - - - -0.3889 - 1.592 0.347 - 181 1 2 0 -0.0004 12 0 0 0 6.45E+07 4.99E+07 - - - 2.8273 0.9683 221125_WJC_METTL3_EV_vs_WT_F04.09018.09018.2 0.000868 13/24 F.AINEAVESGDVGK[136.11].T "sp|P46940|IQGA1_HUMAN,tr|H0YLE8|H0YLE8_HUMAN,tr|A0A0J9YXZ5|A0A0J9YXZ5_HUMAN" 3 1295.6449 1.27 43945 9018 2 1295.640805 648.8297 Ras GTPase-activating-like protein IQGAP1 OS=Homo sapiens OX=9606 GN=IQGAP1 PE=1 SV=1 4.14 2041.1 - 319261 - - - -3.1297 - 2.645 0.472 - 607.4 1 1 0 -0.0041 13 0 0 0 5.84E+06 4.58E+06 - - - 5.0223 0.9998 221125_WJC_METTL3_EV_vs_WT_F04.09021.09021.2 0.00803 18-Nov K.ILAHNNFVGR[166.11].L "sp|Q9NZI8|IF2B1_HUMAN,sp|O00425|IF2B3_HUMAN" 2 1149.6282 2.92 43946 9021 2 1149.629137 575.8214 Insulin-like growth factor 2 mRNA-binding protein 1 OS=Homo sapiens OX=9606 GN=IGF2BP1 PE=1 SV=2 9.76 2041.5 - 3.25E+06 - - - 0.775 - 2.064 0.416 - 489.3 1 2 0 0.0009 10 0 0 0 3.39E+08 1.16E+08 - - - 4.136 0.9162 221125_WJC_METTL3_EV_vs_WT_F04.09023.09023.2 1.33E-05 14-Aug L.AHNNFVGR.L "sp|Q9NZI8|IF2B1_HUMAN,sp|O00425|IF2B3_HUMAN" 2 913.4518 0.96 43948 9023 2 913.448664 457.7332 Insulin-like growth factor 2 mRNA-binding protein 1 OS=Homo sapiens OX=9606 GN=IGF2BP1 PE=1 SV=2 9.8 2041.8 - 882174 - - - -3.4857 - 1.632 0.452 - 288.3 1 1 0 -0.0032 8 0 0 0 4.01E+07 4.18E+07 - - - 3.8557 0.9995 221125_WJC_METTL3_EV_vs_WT_F04.09026.09026.2 5.47E-05 16-Sep K.FFQEENTEK.L sp|O00232|PSD12_HUMAN 1 1170.5193 0.8 43949 9026 2 1170.518784 586.2669 26S proteasome non-ATPase regulatory subunit 12 OS=Homo sapiens OX=9606 GN=PSMD12 PE=1 SV=3 4.25 2042.1 - 1.91E+06 - - - -0.4571 - 1.579 0.365 - 157.6 1 2 0 -0.0005 9 0 0 0 4.70E+07 5.91E+07 - - - 3.0582 0.9605 221125_WJC_METTL3_EV_vs_WT_F04.09027.09027.2 0.0822 16-Dec L.LAHNNFVGR[166.11].L "sp|Q9NZI8|IF2B1_HUMAN,sp|O00425|IF2B3_HUMAN" 2 1036.5442 1.75 43950 9027 2 1036.542903 519.2794 Insulin-like growth factor 2 mRNA-binding protein 1 OS=Homo sapiens OX=9606 GN=IGF2BP1 PE=1 SV=2 9.76 2042.2 - 1.63E+06 - - - -1.2339 - 1.812 0.303 - 467.2 1 1 0 -0.0013 9 0 0 0 7.91E+07 4.53E+07 - - - 2.9983 0.9911 221125_WJC_METTL3_EV_vs_WT_F04.09028.09028.2 0.223 12-Jun K.DNNLLGK[136.11].F "sp|P54652|HSP72_HUMAN,sp|P11142|HSP7C_HUMAN,tr|E9PNE6|E9PNE6_HUMAN,tr|A8K7Q2|A8K7Q2_HUMAN,tr|E9PKE3|E9PKE3_HUMAN,tr|E9PM13|E9PM13_HUMAN,tr|E9PS65|E9PS65_HUMAN" 7 780.4221 0.18 43951 9028 2 780.420954 391.2183 Heat shock-related 70 kDa protein 2 OS=Homo sapiens OX=9606 GN=HSPA2 PE=1 SV=1 5.84 2042.3 - 971533 - - - -1.4915 - 1.236 0.174 - 158.9 1 2 0 -0.0012 7 0 0 0 9.01E+08 5.13E+09 - - - 0.9972 0.9996 221125_WJC_METTL3_EV_vs_WT_F04.09029.09029.2 0.00197 18-Sep K.VVLDQTGVSK[136.11].G sp|Q9NX07|TSAP1_HUMAN 1 1052.5957 0.03 43952 9029 2 1052.594285 527.3051 tRNA selenocysteine 1-associated protein 1 OS=Homo sapiens OX=9606 GN=TRNAU1AP PE=1 SV=1 5.81 2042.5 - 531069 - - - -1.368 - 1.781 0.412 - 259.9 1 2 0 -0.0014 10 0 0 0 3.17E+05 9.35E+06 - - - 3.6947 0.9998 221125_WJC_METTL3_EV_vs_WT_F04.09030.09030.2 1.33E-05 22-Aug R.ITAMDTEDQGVK[136.11].V "sp|Q9H6Z4|RANB3_HUMAN,tr|B7Z7F3|B7Z7F3_HUMAN,tr|K7EIJ4|K7EIJ4_HUMAN" 3 1314.6217 0.28 43953 9030 2 1314.620672 658.3181 Ran-binding protein 3 OS=Homo sapiens OX=9606 GN=RANBP3 PE=1 SV=1 4.03 2042.6 - 429673 - - - -0.7683 - 1.729 0.477 - 126 1 2 0 -0.001 12 0 0 0 1.45E+06 5.22E+06 - - - 4.0045 0.9999 221125_WJC_METTL3_EV_vs_WT_F04.09033.09033.2 0.000223 16-Aug K.VTMQNLNDR.L "sp|P13645|K1C10_HUMAN,sp|Q7Z3Z0|K1C25_HUMAN,sp|Q7Z3Y9|K1C26_HUMAN,sp|P02533|K1C14_HUMAN,sp|Q7Z3Y8|K1C27_HUMAN,sp|P08779|K1C16_HUMAN,sp|Q7Z3Y7|K1C28_HUMAN,tr|A0A1B0GVI3|A0A1B0GVI3_HUMAN" 8 1089.5237 1735.09 43954 9033 2 1089.523739 545.7691 "Keratin, type I cytoskeletal 10 OS=Homo sapiens OX=9606 GN=KRT10 PE=1 SV=6" 5.81 2043 - 1.07E+09 - - - 0.0431 - 1.926 0.567 - 383.9 1 2 0 0 9 0 0 0 2.22E+10 1.28E+07 - - - 5.1251 0.9998 221125_WJC_METTL3_EV_vs_WT_F04.09035.09035.2 0.00232 13/22 K.VIAAEGEMNASR.A sp|P27105|STOM_HUMAN 1 1246.5976 1.13 43956 9035 2 1246.595634 624.3061 Stomatin OS=Homo sapiens OX=9606 GN=STOM PE=1 SV=3 4.53 2043.2 - 524475 - - - -1.5659 - 2.385 0.488 - 525 1 2 0 -0.002 12 0 0 0 4.96E+07 4.40E+07 - - - 4.9318 0.9999 221125_WJC_METTL3_EV_vs_WT_F04.09038.09038.2 0.0016 16-Sep K.DVDGAYMTK.V sp|P04264|K2C1_HUMAN 1 998.4379 41.02 43957 9038 2 998.438042 500.2262 "Keratin, type II cytoskeletal 1 OS=Homo sapiens OX=9606 GN=KRT1 PE=1 SV=6" 4.21 2043.5 - 867947 - - - 0.1452 - 1.664 0.55 - 179.7 1 2 0 0.0001 9 0 0 0 2.50E+07 6.10E+05 - - - 4.5765 0.9966 221125_WJC_METTL3_EV_vs_WT_F04.09039.09039.2 0.000427 14-Aug R.VGLFHSDR.S "sp|Q8IXK0|PHC2_HUMAN,tr|A0A0A0MSI2|A0A0A0MSI2_HUMAN,tr|B3KPJ4|B3KPJ4_HUMAN" 3 929.4719 1.66 43958 9039 2 929.468292 465.7432 Polyhomeotic-like protein 2 OS=Homo sapiens OX=9606 GN=PHC2 PE=1 SV=1 6.71 2043.7 - 735054 - - - -3.8979 - 1.529 0.401 - 195.3 1 2 0 -0.0036 8 0 0 0 1.99E+07 1.20E+07 - - - 3.2823 0.991 221125_WJC_METTL3_EV_vs_WT_F04.09040.09040.2 0.0555 18-Sep K.TLTQGGVTYR[166.11].D sp|Q13643|FHL3_HUMAN 1 1104.5803 0.57 43959 9040 2 1104.57641 553.2974 Four and a half LIM domains protein 3 OS=Homo sapiens OX=9606 GN=FHL3 PE=1 SV=4 8.41 2043.8 - 1.31E+06 - - - -3.5154 - 1.713 0.21 - 242.2 1 2 0 -0.0039 10 0 0 0 1.00E+07 1.75E+07 - - - 2.0932 0.9984 221125_WJC_METTL3_EV_vs_WT_F04.09047.09047.2 0.000503 16-Sep K.GFGDVGEAK.G "sp|Q14157|UBP2L_HUMAN,tr|F8W726|F8W726_HUMAN" 2 878.4134 1.82 43964 9047 2 878.410732 440.214 Ubiquitin-associated protein 2-like OS=Homo sapiens OX=9606 GN=UBAP2L PE=1 SV=2 4.37 2044.7 - 1.23E+06 - - - -3.0339 - 1.515 0.431 - 237.9 1 2 0 -0.0027 9 0 0 0 5.31E+07 2.91E+07 - - - 3.4253 0.997 221125_WJC_METTL3_EV_vs_WT_F04.09051.09051.2 0.0675 14-Jun R.ESVFTNER.F sp|O43709|BUD23_HUMAN 1 980.4563 0.64 43967 9051 2 980.454073 491.2354 Probable 18S rRNA (guanine-N(7))-methyltransferase OS=Homo sapiens OX=9606 GN=BUD23 PE=1 SV=2 4.53 2045.2 - 2.16E+06 - - - -2.2959 - 1.435 0.291 - 150 1 2 0 -0.0023 8 0 0 0 1.03E+08 1.60E+08 - - - 2.2789 0.9965 221125_WJC_METTL3_EV_vs_WT_F04.09054.09054.2 0.329 14-Jul R.SLQAQLQR.L "sp|Q9NTJ5|SAC1_HUMAN,tr|E9PGZ4|E9PGZ4_HUMAN,tr|A0A5F9ZHN7|A0A5F9ZHN7_HUMAN,tr|C9JV50|C9JV50_HUMAN" 4 942.5247 0.91 43969 9054 2 942.525769 472.2696 Phosphatidylinositol-3-phosphatase SAC1 OS=Homo sapiens OX=9606 GN=SACM1L PE=1 SV=2 9.47 2045.6 - 978745 - - - 1.1565 - 1.422 0.206 - 180.5 1 2 0 0.0011 8 0 0 0 1.71E+07 1.87E+07 - - - 1.624 0.9939 221125_WJC_METTL3_EV_vs_WT_F04.09055.09055.2 0.00573 16-Jul R.NVPVITGSK[136.11].D "sp|P35232|PHB_HUMAN,tr|E7ESE2|E7ESE2_HUMAN,tr|E9PCW0|E9PCW0_HUMAN,tr|C9JW96|C9JW96_HUMAN" 4 921.5375 1.3 43970 9055 2 921.535113 461.776 Prohibitin OS=Homo sapiens OX=9606 GN=PHB PE=1 SV=1 8.75 2045.7 - 1.75E+06 - - - -2.5707 - 1.401 0.248 - 140.3 1 2 0 -0.0024 9 0 0 0 2.34E+08 1.80E+08 - - - 1.8475 0.9994 221125_WJC_METTL3_EV_vs_WT_F04.09061.09061.2 0.00372 14-Aug K.STSIQSFK[136.11].D "sp|P13797|PLST_HUMAN,tr|A0A0A0MSQ0|A0A0A0MSQ0_HUMAN" 2 904.4745 0.46 43974 9061 2 904.472943 453.2445 Plastin-3 OS=Homo sapiens OX=9606 GN=PLS3 PE=1 SV=4 8.47 2046.4 - 1.84E+06 - - - -1.7734 - 1.911 0.35 - 333.6 1 2 0 -0.0016 8 0 0 0 2.16E+07 4.68E+07 - - - 3.5788 0.9992 221125_WJC_METTL3_EV_vs_WT_F04.09062.09062.2 0.000651 18-Sep K.ASPQPALTVK.A "sp|Q8N9M1|CS047_HUMAN,tr|J3QS80|J3QS80_HUMAN,tr|A0A2R8Y6U9|A0A2R8Y6U9_HUMAN,tr|A0A804HLH2|A0A804HLH2_HUMAN" 4 1010.576 1.21 43975 9062 2 1010.577007 506.2953 Uncharacterized protein C19orf47 OS=Homo sapiens OX=9606 GN=C19orf47 PE=1 SV=1 8.8 2046.5 - 1.57E+06 - - - 0.9509 - 1.486 0.369 - 245.9 1 2 0 0.001 10 0 0 0 2.27E+07 1.87E+07 - - - 2.8717 0.9992 221125_WJC_METTL3_EV_vs_WT_F04.09063.09063.2 0.127 14-Aug R.SLQAQLQR[166.11].L "sp|Q9NTJ5|SAC1_HUMAN,tr|E9PGZ4|E9PGZ4_HUMAN,tr|A0A5F9ZHN7|A0A5F9ZHN7_HUMAN,tr|C9JV50|C9JV50_HUMAN" 4 952.5329 0.94 43976 9063 2 952.531685 477.2738 Phosphatidylinositol-3-phosphatase SAC1 OS=Homo sapiens OX=9606 GN=SACM1L PE=1 SV=2 9.47 2046.6 - 1.17E+06 - - - -1.327 - 1.496 0.352 - 266.6 1 2 0 -0.0013 8 0 0 0 1.71E+07 1.81E+07 - - - 2.8553 0.9995 221125_WJC_METTL3_EV_vs_WT_F04.09065.09065.2 0.023 16-Sep K.ASGFEESMK.W "sp|Q6P2Q9|PRP8_HUMAN,tr|I3L3Z8|I3L3Z8_HUMAN" 2 984.4222 2.04 43978 9065 2 984.42113 493.2184 Pre-mRNA-processing-splicing factor 8 OS=Homo sapiens OX=9606 GN=PRPF8 PE=1 SV=2 4.53 2046.9 - 1.06E+06 - - - -1.1347 - 1.869 0.336 - 338 1 2 0 -0.0011 9 0 0 0 2.66E+07 1.30E+07 - - - 3.3317 0.9991 221125_WJC_METTL3_EV_vs_WT_F04.09066.09066.2 0.0192 14-Jul R.DAMNLSGR[166.11].R "sp|Q9H4A3|WNK1_HUMAN,tr|F5GWT4|F5GWT4_HUMAN,tr|A0A6Q8PFM0|A0A6Q8PFM0_HUMAN" 3 872.405 0.45 43979 9066 2 872.404816 437.2098 Serine\threonine-protein kinase WNK1 OS=Homo sapiens OX=9606 GN=WNK1 PE=1 SV=2 5.84 2047 - 901988 - - - -0.1777 - 1.47 0.302 - 172.2 1 2 0 -0.0002 8 0 0 0 2.35E+07 5.24E+07 - - - 2.4335 0.9998 221125_WJC_METTL3_EV_vs_WT_F04.09067.09067.2 8.90E-05 22-Nov K.VIQIATSSSTAK.N "sp|Q7L2E3|DHX30_HUMAN,tr|H7BXY3|H7BXY3_HUMAN" 2 1204.6663 1.57 43980 9067 2 1204.666658 603.3404 ATP-dependent RNA helicase DHX30 OS=Homo sapiens OX=9606 GN=DHX30 PE=1 SV=1 8.72 2047.1 - 755907 - - - 0.2831 - 2.092 0.45 - 379.6 1 2 0 0.0003 12 0 0 0 1.91E+07 1.22E+07 - - - 4.3067 0.9998 221125_WJC_METTL3_EV_vs_WT_F04.09068.09068.2 0.00563 20-Jul K.LNDGSQITYEK[136.11].C "sp|O95831|AIFM1_HUMAN,tr|A0A6Q8PFW2|A0A6Q8PFW2_HUMAN,tr|A0A6Q8PFA7|A0A6Q8PFA7_HUMAN,tr|A0A6Q8PHJ9|A0A6Q8PHJ9_HUMAN,tr|A0A6Q8PFS4|A0A6Q8PFS4_HUMAN,tr|A0A7I2PK44|A0A7I2PK44_HUMAN,tr|A0A6Q8PG15|A0A6Q8PG15_HUMAN,tr|A0A6Q8PFE1|A0A6Q8PFE1_HUMAN,tr|A0A7I2RLJ8|A0A7I2RLJ8_HUMAN,tr|A0A6Q8PFQ8|A0A6Q8PFQ8_HUMAN,tr|A0A6Q8PHC0|A0A6Q8PHC0_HUMAN,tr|A0A6Q8PFM5|A0A6Q8PFM5_HUMAN" 12 1274.6234 0.79 43981 9068 2 1274.624468 638.319 "Apoptosis-inducing factor 1, mitochondrial OS=Homo sapiens OX=9606 GN=AIFM1 PE=1 SV=1" 4.37 2047.3 - 562963 - - - 0.841 - 2.013 0.427 - 231.8 1 2 0 0.0011 11 0 0 0 5.40E+06 6.85E+06 - - - 4.0871 0.999 221125_WJC_METTL3_EV_vs_WT_F04.09073.09073.2 0.00403 12-Jun K.DNNLLGK.F "sp|P54652|HSP72_HUMAN,sp|P11142|HSP7C_HUMAN,tr|E9PNE6|E9PNE6_HUMAN,tr|A8K7Q2|A8K7Q2_HUMAN,tr|E9PKE3|E9PKE3_HUMAN,tr|E9PM13|E9PM13_HUMAN,tr|E9PS65|E9PS65_HUMAN" 7 772.4079 0.18 43984 9073 2 772.40706 387.2112 Heat shock-related 70 kDa protein 2 OS=Homo sapiens OX=9606 GN=HSPA2 PE=1 SV=1 5.84 2047.9 - 1.19E+07 - - - -1.1108 - 1.418 0.33 - 208.1 1 2 0 -0.0009 7 0 0 0 9.01E+08 5.13E+09 - - - 2.5847 0.9987 221125_WJC_METTL3_EV_vs_WT_F04.09074.09074.2 0.00076 16-Aug R.NVPVITGSK.D "sp|P35232|PHB_HUMAN,tr|E7ESE2|E7ESE2_HUMAN,tr|E9PCW0|E9PCW0_HUMAN,tr|C9JW96|C9JW96_HUMAN" 4 913.5233 1.3 43985 9074 2 913.522058 457.7689 Prohibitin OS=Homo sapiens OX=9606 GN=PHB PE=1 SV=1 8.75 2048 - 4.46E+06 - - - -1.3399 - 1.39 0.333 - 185.4 1 2 0 -0.0012 9 0 0 0 2.34E+08 1.80E+08 - - - 2.4528 0.9985 221125_WJC_METTL3_EV_vs_WT_F04.09076.09076.2 0.00403 16-Sep K.ASGFEESMK[136.11].W "sp|Q6P2Q9|PRP8_HUMAN,tr|I3L3Z8|I3L3Z8_HUMAN" 2 992.4364 2.05 43987 9076 2 992.434472 497.2255 Pre-mRNA-processing-splicing factor 8 OS=Homo sapiens OX=9606 GN=PRPF8 PE=1 SV=2 4.53 2048.1 - 1.02E+06 - - - -1.9901 - 1.783 0.266 - 333.6 1 2 0 -0.002 9 0 0 0 2.66E+07 1.30E+07 - - - 2.6781 0.9998 221125_WJC_METTL3_EV_vs_WT_F04.09077.09077.2 0.000117 22-Oct R.TQPMTAQAASYR.A sp|Q96PK6|RBM14_HUMAN 1 1323.6241 2.01 43988 9077 2 1323.623421 662.8193 RNA-binding protein 14 OS=Homo sapiens OX=9606 GN=RBM14 PE=1 SV=2 8.41 2048.2 - 593640 - - - -0.5394 - 1.808 0.534 - 360.4 1 2 0 -0.0007 12 0 0 0 8.79E+06 4.37E+06 - - - 4.5431 0.9996 221125_WJC_METTL3_EV_vs_WT_F04.09078.09078.2 0.00982 20-Sep K.YEEIDNAPEER.A sp|P49411|EFTU_HUMAN 1 1363.5892 2.04 43989 9078 2 1363.590053 682.8019 "Elongation factor Tu, mitochondrial OS=Homo sapiens OX=9606 GN=TUFM PE=1 SV=2" 3.91 2048.4 - 532500 - - - 0.6336 - 1.507 0.438 - 197.4 1 2 0 0.0009 11 0 0 0 3.75E+07 1.84E+07 - - - 3.3853 0.999 221125_WJC_METTL3_EV_vs_WT_F04.09081.09081.2 0.0442 22-Jun R.TQPMTAQAASYR[166.11].A sp|Q96PK6|RBM14_HUMAN 1 1333.6324 2 43992 9081 2 1333.633515 667.8235 RNA-binding protein 14 OS=Homo sapiens OX=9606 GN=RBM14 PE=1 SV=2 8.41 2048.8 - 376371 - - - 0.8323 - 1.353 0.37 - 91 1 2 0 0.0011 12 0 0 0 8.71E+06 4.37E+06 - - - 2.5689 0.9564 221125_WJC_METTL3_EV_vs_WT_F04.09082.09082.2 11 20-May K.LNDGSQITYEK.C "sp|O95831|AIFM1_HUMAN,tr|A0A6Q8PFW2|A0A6Q8PFW2_HUMAN,tr|A0A6Q8PFA7|A0A6Q8PFA7_HUMAN,tr|A0A6Q8PHJ9|A0A6Q8PHJ9_HUMAN,tr|A0A6Q8PFS4|A0A6Q8PFS4_HUMAN,tr|A0A7I2PK44|A0A7I2PK44_HUMAN,tr|A0A6Q8PG15|A0A6Q8PG15_HUMAN,tr|A0A6Q8PFE1|A0A6Q8PFE1_HUMAN,tr|A0A7I2RLJ8|A0A7I2RLJ8_HUMAN,tr|A0A6Q8PFQ8|A0A6Q8PFQ8_HUMAN,tr|A0A6Q8PHC0|A0A6Q8PHC0_HUMAN,tr|A0A6Q8PFM5|A0A6Q8PFM5_HUMAN" 12 1266.6092 0.79 43993 9082 2 1266.609095 634.3119 "Apoptosis-inducing factor 1, mitochondrial OS=Homo sapiens OX=9606 GN=AIFM1 PE=1 SV=1" 4.37 2048.9 - 250740 - - - -0.0797 - 1.074 0.107 - 51 7 2 0 -0.0001 11 0 0 0 5.40E+06 6.85E+06 - - - -0.3531 0.9998 221125_WJC_METTL3_EV_vs_WT_F04.09083.09083.2 0.00154 20-Oct R.SGMVQTEAQYR[166.11].F "sp|Q06124|PTN11_HUMAN,tr|A0A0U1RRI0|A0A0U1RRI0_HUMAN" 2 1278.5902 0.09 43994 9083 2 1278.589523 640.3024 Tyrosine-protein phosphatase non-receptor type 11 OS=Homo sapiens OX=9606 GN=PTPN11 PE=1 SV=3 5.72 2049 - 227486 - - - -0.5342 - 1.76 0.477 - 351.9 1 2 0 -0.0007 11 0 0 0 2.08E+05 2.26E+06 - - - 4.0932 0.9981 221125_WJC_METTL3_EV_vs_WT_F04.09086.09086.2 0.0137 12-Jul R.TGYNFQR[166.11].V sp|O43660|PLRG1_HUMAN 1 894.4223 1.54 43995 9086 2 894.421222 448.2184 Pleiotropic regulator 1 OS=Homo sapiens OX=9606 GN=PLRG1 PE=1 SV=1 8.41 2049.4 - 2.01E+06 - - - -1.2455 - 1.491 0.242 - 208.4 1 2 0 -0.0011 7 0 0 0 6.97E+07 4.53E+07 - - - 2.0937 0.9991 221125_WJC_METTL3_EV_vs_WT_F04.09087.09087.2 0.000136 16-Nov R.SQAASILTK[136.11].F sp|O95347|SMC2_HUMAN 1 925.5324 0.68 43996 9087 2 925.533956 463.7735 Structural maintenance of chromosomes protein 2 OS=Homo sapiens OX=9606 GN=SMC2 PE=1 SV=2 8.47 2049.5 - 1.65E+06 - - - 1.6855 - 2.198 0.241 - 496.7 1 2 0 0.0016 9 0 0 0 1.55E+07 2.27E+07 - - - 3.099 0.9738 221125_WJC_METTL3_EV_vs_WT_F04.09089.09089.2 2.58 12-May K.TTSLTEK[136.11].K sp|Q5T7N2|LITD1_HUMAN 1 786.4214 57.28 43998 9089 2 786.420574 394.218 LINE-1 type transposase domain-containing protein 1 OS=Homo sapiens OX=9606 GN=L1TD1 PE=1 SV=1 5.66 2049.6 - 3.29E+06 - - - -1.1126 - 1.109 0.103 - 105.5 1 2 0 -0.0009 7 0 0 0 1.85E+09 3.23E+07 - - - 0.1293 0.9934 221125_WJC_METTL3_EV_vs_WT_F04.09090.09090.2 0.229 16-Aug R.LQAEISNVK.K sp|Q7Z794|K2C1B_HUMAN 1 1000.5553 0.62 43999 9090 2 1000.557961 501.2849 "Keratin, type II cytoskeletal 1b OS=Homo sapiens OX=9606 GN=KRT77 PE=1 SV=3" 6 2049.7 - 1.24E+06 - - - 2.6495 - 1.673 0.179 - 155.6 1 2 0 0.0027 9 0 0 0 1.34E+07 2.16E+07 - - - 1.8511 0.9998 221125_WJC_METTL3_EV_vs_WT_F04.09091.09091.2 0.0564 13/20 K.QAQILASEAEK[136.11].A "sp|Q9UJZ1|STML2_HUMAN,tr|A0A087WYB4|A0A087WYB4_HUMAN,tr|F2Z2I8|F2Z2I8_HUMAN" 3 1194.6336 2.05 44000 9091 2 1194.631903 598.3241 "Stomatin-like protein 2, mitochondrial OS=Homo sapiens OX=9606 GN=STOML2 PE=1 SV=1" 4.53 2049.8 - 1.07E+06 - - - -1.3929 - 2.863 0.399 - 735.1 1 2 0 -0.0017 11 0 0 0 1.23E+08 6.01E+07 - - - 4.833 0.9993 221125_WJC_METTL3_EV_vs_WT_F04.09093.09093.2 0.00354 14-Jul R.NQLQSVYK.M sp|Q9BSM1|PCGF1_HUMAN 1 978.5134 1.14 44002 9093 2 978.5129 490.264 Polycomb group RING finger protein 1 OS=Homo sapiens OX=9606 GN=PCGF1 PE=1 SV=2 8.59 2050 - 984052 - - - -0.557 - 1.706 0.288 - 285.9 1 2 0 -0.0005 8 0 0 0 2.22E+07 1.95E+07 - - - 2.779 0.9996 221125_WJC_METTL3_EV_vs_WT_F04.09094.09094.2 0.00199 14-Sep R.NQLQSVYK[136.11].M sp|Q9BSM1|PCGF1_HUMAN 1 986.5276 1.14 44003 9094 2 986.526377 494.2711 Polycomb group RING finger protein 1 OS=Homo sapiens OX=9606 GN=PCGF1 PE=1 SV=2 8.59 2050.2 - 945046 - - - -1.2853 - 1.79 0.382 - 471.6 1 2 0 -0.0013 8 0 0 0 2.22E+07 1.95E+07 - - - 3.618 0.9985 221125_WJC_METTL3_EV_vs_WT_F04.09098.09098.2 0.0211 14-Sep R.NASVPNLR.G "sp|Q9H019|MFR1L_HUMAN,tr|E9PLD2|E9PLD2_HUMAN,tr|E9PPQ0|E9PPQ0_HUMAN,tr|E9PRK5|E9PRK5_HUMAN,tr|E9PNJ0|E9PNJ0_HUMAN,tr|E9PPF9|E9PPF9_HUMAN,tr|E9PSD6|E9PSD6_HUMAN,tr|E9PRW1|E9PRW1_HUMAN,tr|C9JF50|C9JF50_HUMAN,tr|E9PLU1|E9PLU1_HUMAN" 10 869.4719 2.15 44006 9098 2 869.470577 435.7432 Mitochondrial fission regulator 1-like OS=Homo sapiens OX=9606 GN=MTFR1L PE=1 SV=2 9.75 2050.6 - 3.41E+06 - - - -1.5389 - 1.494 0.291 - 397.9 1 2 0 -0.0013 8 0 0 0 5.29E+07 2.46E+07 - - - 2.4007 0.9999 221125_WJC_METTL3_EV_vs_WT_F04.09099.09099.2 0.000173 20-Dec K.QAQILASEAEK.A "sp|Q9UJZ1|STML2_HUMAN,tr|A0A087WYB4|A0A087WYB4_HUMAN,tr|F2Z2I8|F2Z2I8_HUMAN" 3 1186.6194 1.97 44007 9099 2 1186.619002 594.317 "Stomatin-like protein 2, mitochondrial OS=Homo sapiens OX=9606 GN=STOML2 PE=1 SV=1" 4.53 2050.7 - 2.35E+06 - - - -0.3076 - 2.334 0.486 - 619.9 1 2 0 -0.0004 11 0 0 0 1.35E+08 6.87E+07 - - - 4.9234 0.9996 221125_WJC_METTL3_EV_vs_WT_F04.09100.09100.2 0.0418 20-Aug R.VEIIANDQGNR[166.11].L "sp|P11021|BIP_HUMAN,sp|P48741|HSP77_HUMAN,sp|P54652|HSP72_HUMAN,sp|P0DMV8|HS71A_HUMAN,sp|P34931|HS71L_HUMAN,sp|P11142|HSP7C_HUMAN,sp|P0DMV9|HS71B_HUMAN,sp|P17066|HSP76_HUMAN,tr|E9PQQ4|E9PQQ4_HUMAN,tr|E9PNE6|E9PNE6_HUMAN,tr|E9PKE3|E9PKE3_HUMAN,tr|A0A7P0TB36|A0A7P0TB36_HUMAN,tr|E9PLF4|E9PLF4_HUMAN,tr|A0A7P0TAI0|A0A7P0TAI0_HUMAN,tr|Q53FA3|Q53FA3_HUMAN,tr|E9PI65|E9PI65_HUMAN,tr|E9PK54|E9PK54_HUMAN,tr|E9PN25|E9PN25_HUMAN,tr|E9PPY6|E9PPY6_HUMAN,tr|E9PQK7|E9PQK7_HUMAN,tr|A0A0G2JIW1|A0A0G2JIW1_HUMAN" 21 1237.629 0.17 44008 9100 2 1237.62791 619.8218 Endoplasmic reticulum chaperone BiP OS=Homo sapiens OX=9606 GN=HSPA5 PE=1 SV=2 4.37 2050.8 - 882548 - - - -0.9082 - 1.971 0.336 - 216.8 1 2 0 -0.0011 11 0 0 0 3.60E+07 2.09E+08 - - - 3.358 0.9999 221125_WJC_METTL3_EV_vs_WT_F04.09101.09101.2 0.00498 16-Aug R.LSSYTEC[160.03]YK[136.11].W "sp|Q8IWC1|MA7D3_HUMAN,tr|A0A0A0MRP0|A0A0A0MRP0_HUMAN" 2 1157.5154 1.29 44009 9101 2 1157.51506 579.765 MAP7 domain-containing protein 3 OS=Homo sapiens OX=9606 GN=MAP7D3 PE=1 SV=2 5.99 2050.9 - 862952 - - - -0.3162 - 1.939 0.555 - 195 1 2 0 -0.0004 9 0 0 0 1.36E+07 1.06E+07 - - - 5.0558 0.9995 221125_WJC_METTL3_EV_vs_WT_F04.09102.09102.2 0.000949 16-Jul R.LSSYTEC[160.03]YK.W "sp|Q8IWC1|MA7D3_HUMAN,tr|A0A0A0MRP0|A0A0A0MRP0_HUMAN" 2 1149.5012 1.29 44010 9102 2 1149.50157 575.7579 MAP7 domain-containing protein 3 OS=Homo sapiens OX=9606 GN=MAP7D3 PE=1 SV=2 5.99 2051 - 848109 - - - 0.2993 - 1.446 0.411 - 117.3 1 2 0 0.0003 9 0 0 0 1.36E+07 1.06E+07 - - - 3.1435 0.9998 221125_WJC_METTL3_EV_vs_WT_F04.09103.09103.2 0.0227 16-Dec K.EGLQNMEAR[166.11].L "sp|P31948|STIP1_HUMAN,tr|F5GXD8|F5GXD8_HUMAN,tr|F5H783|F5H783_HUMAN" 3 1056.4898 1.31 44011 9103 2 1056.489358 529.2522 Stress-induced-phosphoprotein 1 OS=Homo sapiens OX=9606 GN=STIP1 PE=1 SV=1 4.53 2051.2 - 826278 - - - -0.3833 - 2.274 0.355 - 459.1 1 2 0 -0.0004 9 0 0 0 1.94E+07 1.48E+07 - - - 4.0397 0.9811 221125_WJC_METTL3_EV_vs_WT_F04.09104.09104.2 0.23 12-Jun R.INIPPQR[166.11].G "sp|Q13283|G3BP1_HUMAN,tr|A0A7I2V5M7|A0A7I2V5M7_HUMAN,tr|A0A7P0P2U7|A0A7P0P2U7_HUMAN,tr|A0A7I2YQU8|A0A7I2YQU8_HUMAN,tr|A0A7I2V548|A0A7I2V548_HUMAN,tr|A0A7I2V565|A0A7I2V565_HUMAN,tr|A0A7I2YQN9|A0A7I2YQN9_HUMAN" 7 846.4951 1.48 44012 9104 2 846.491942 424.2548 Ras GTPase-activating protein-binding protein 1 OS=Homo sapiens OX=9606 GN=G3BP1 PE=1 SV=1 9.75 2051.3 - 631889 - - - -3.7389 - 1.55 0.161 - 142.7 1 2 0 -0.0032 7 0 0 0 1.63E+07 1.11E+07 - - - 1.6178 0.9799 221125_WJC_METTL3_EV_vs_WT_F04.09105.09105.2 0.0227 12-Jun K.DPSDYVR.A "sp|Q9BTD8|RBM42_HUMAN,tr|K7EQ03|K7EQ03_HUMAN,tr|K7EML2|K7EML2_HUMAN,tr|K7EP90|K7EP90_HUMAN" 4 850.3821 0.33 44013 9105 2 850.384838 426.1983 RNA-binding protein 42 OS=Homo sapiens OX=9606 GN=RBM42 PE=1 SV=1 4.21 2051.4 - 511417 - - - 3.2233 - 1.328 0.185 - 177.9 1 2 0 0.0027 7 0 0 0 1.60E+07 4.87E+07 - - - 1.3054 1 221125_WJC_METTL3_EV_vs_WT_F04.09106.09106.2 2.35E-07 20-Nov K.YEEIDNAPEER[166.11].A sp|P49411|EFTU_HUMAN 1 1373.5975 2.04 44014 9106 2 1373.598728 687.806 "Elongation factor Tu, mitochondrial OS=Homo sapiens OX=9606 GN=TUFM PE=1 SV=2" 3.91 2051.6 - 410358 - - - 0.9239 - 2.33 0.689 - 523.8 1 2 0 0.0013 11 0 0 0 3.75E+07 1.84E+07 - - - 6.4178 0.9994 221125_WJC_METTL3_EV_vs_WT_F04.09110.09110.2 0.0102 12-Aug K.QQAWIQK[136.11].L sp|Q9NX58|LYAR_HUMAN 1 908.496 0.48 44016 9110 2 908.495551 455.2553 Cell growth-regulating nucleolar protein OS=Homo sapiens OX=9606 GN=LYAR PE=1 SV=2 8.75 2052 - 2.80E+06 - - - -0.4403 - 1.459 0.349 - 308.4 1 2 0 -0.0004 7 0 0 0 1.55E+07 3.23E+07 - - - 2.8155 0.9996 221125_WJC_METTL3_EV_vs_WT_F04.09112.09112.2 0.0786 16-Sep R.FQAQLESEK.N "sp|P82094|TMF1_HUMAN,tr|A0A2R8Y7M0|A0A2R8Y7M0_HUMAN" 2 1078.5295 1.44 44018 9112 2 1078.528904 540.272 TATA element modulatory factor OS=Homo sapiens OX=9606 GN=TMF1 PE=1 SV=2 4.53 2052.2 - 1.46E+06 - - - -0.5424 - 1.933 0.302 - 184 1 2 0 -0.0006 9 0 0 0 1.52E+08 1.06E+08 - - - 3.1781 0.9194 221125_WJC_METTL3_EV_vs_WT_F04.09120.09120.2 0.0005 16-Dec K.YLKDVTLQK.Q "sp|P18621|RL17_HUMAN,tr|A0A087WWH0|A0A087WWH0_HUMAN,tr|J3QS96|J3QS96_HUMAN,tr|J3QLC8|J3QLC8_HUMAN,tr|J3QQT2|J3QQT2_HUMAN,tr|J3KSJ0|J3KSJ0_HUMAN,tr|A0A087WY81|A0A087WY81_HUMAN,tr|A0A0A0MRF8|A0A0A0MRF8_HUMAN,tr|J3KRB3|J3KRB3_HUMAN,tr|J3KRX5|J3KRX5_HUMAN,tr|A0A087WXM6|A0A087WXM6_HUMAN,tr|A0A0A6YYL6|A0A0A6YYL6_HUMAN" 12 1106.6336 0.9 44024 9120 2 1106.636334 554.3241 60S ribosomal protein L17 OS=Homo sapiens OX=9606 GN=RPL17 PE=1 SV=3 8.5 2053.1 - 1.25E+06 - - - 2.5067 - 1.629 0.162 - 388.8 1 2 1 0.0028 9 0 0 0 1.13E+07 1.24E+07 - - - 1.6484 0.9996 221125_WJC_METTL3_EV_vs_WT_F04.09121.09121.2 0.00117 14-Sep K.MMVAGFK[136.11]K[136.11].Q "sp|Q00839|HNRPU_HUMAN,tr|A0A1W2PQL0|A0A1W2PQL0_HUMAN,tr|A0A1W2PPL4|A0A1W2PPL4_HUMAN,tr|A0A1W2PQ74|A0A1W2PQ74_HUMAN,tr|Q5RI18|Q5RI18_HUMAN,tr|A0A1W2PP35|A0A1W2PP35_HUMAN,tr|A0A1W2PPS1|A0A1W2PPS1_HUMAN,tr|A0A1W2PRZ7|A0A1W2PRZ7_HUMAN,tr|A0A1W2PPH7|A0A1W2PPH7_HUMAN,tr|A0A1W2PQD4|A0A1W2PQD4_HUMAN,tr|A0A1W2PP34|A0A1W2PP34_HUMAN,tr|A0A1X7SBS1|A0A1X7SBS1_HUMAN" 12 926.5053 0.72 44025 9121 2 926.504184 464.2599 Heterogeneous nuclear ribonucleoprotein U OS=Homo sapiens OX=9606 GN=HNRNPU PE=1 SV=6 10 2053.2 - 1.51E+06 - - - -1.1678 - 1.822 0.354 - 338.9 1 2 0 -0.0011 8 0 0 0 1.63E+07 2.27E+07 - - - 3.4647 0.9999 221125_WJC_METTL3_EV_vs_WT_F04.09123.09123.2 2.25E-05 18-Nov K.LTDQVMQNPR[166.11].V "sp|Q99733|NP1L4_HUMAN,tr|E9PP22|E9PP22_HUMAN,tr|E9PKI2|E9PKI2_HUMAN,tr|C9J1B1|C9J1B1_HUMAN,tr|C9J6D1|C9J6D1_HUMAN,tr|E9PJJ2|E9PJJ2_HUMAN,tr|E9PNW0|E9PNW0_HUMAN,tr|E9PKT8|E9PKT8_HUMAN,tr|E9PS34|E9PS34_HUMAN,tr|C9JZI7|C9JZI7_HUMAN,tr|E9PNJ7|E9PNJ7_HUMAN" 11 1210.6004 0.76 44027 9123 2 1210.598961 606.3075 Nucleosome assembly protein 1-like 4 OS=Homo sapiens OX=9606 GN=NAP1L4 PE=1 SV=1 5.84 2053.4 - 375663 - - - -1.1688 - 2.358 0.536 - 589.7 1 2 0 -0.0014 10 0 0 0 8.22E+06 1.09E+07 - - - 5.3939 0.9997 221125_WJC_METTL3_EV_vs_WT_F04.09128.09128.2 0.00075 16-Sep R.TTDGSLQIR.V sp|Q06787|FMR1_HUMAN 1 989.5142 0.74 44030 9128 2 989.514911 495.7644 Synaptic functional regulator FMR1 OS=Homo sapiens OX=9606 GN=FMR1 PE=1 SV=1 5.5 2054.1 - 1.23E+06 - - - 0.7448 - 2.188 0.348 - 429 1 2 0 0.0007 9 0 0 0 1.57E+08 2.12E+08 - - - 3.8763 0.9199 221125_WJC_METTL3_EV_vs_WT_F04.09129.09129.2 0.000422 14-Aug Y.GFVHIEDK.T "sp|Q9BWF3|RBM4_HUMAN,sp|Q9BQ04|RBM4B_HUMAN,tr|E9PM61|E9PM61_HUMAN,tr|D6R9K7|D6R9K7_HUMAN,tr|J3QRR5|J3QRR5_HUMAN,tr|E9PB51|E9PB51_HUMAN,tr|U3KQD5|U3KQD5_HUMAN,tr|E9PLB0|E9PLB0_HUMAN" 8 943.4763 3.21 44031 9129 2 943.473804 472.7454 RNA-binding protein 4 OS=Homo sapiens OX=9606 GN=RBM4 PE=1 SV=1 5.32 2054.2 - 1.26E+06 - - - -2.6784 - 1.735 0.342 - 258.8 1 1 0 -0.0025 8 0 0 0 2.22E+07 6.89E+06 - - - 3.228 0.9992 221125_WJC_METTL3_EV_vs_WT_F04.09130.09130.2 0.00105 18-Sep K.GGEIQPVSVK.V "sp|P61604|CH10_HUMAN,tr|B8ZZ54|B8ZZ54_HUMAN,tr|B8ZZL8|B8ZZL8_HUMAN" 3 1012.5553 1.15 44032 9130 2 1012.553522 507.2849 "10 kDa heat shock protein, mitochondrial OS=Homo sapiens OX=9606 GN=HSPE1 PE=1 SV=2" 6 2054.2 - 1.88E+06 - - - -1.7658 - 1.712 0.349 - 286.6 1 2 0 -0.0018 10 0 0 0 7.54E+07 6.56E+07 - - - 3.1189 0.9992 221125_WJC_METTL3_EV_vs_WT_F04.09131.09131.2 0.000337 22-Dec R.AGGPTTPLSPTR.L "sp|P20700|LMNB1_HUMAN,tr|A0A0D9SFY5|A0A0D9SFY5_HUMAN,tr|E9PBF6|E9PBF6_HUMAN,tr|A0A0D9SFE5|A0A0D9SFE5_HUMAN" 4 1153.6091 1.05 44033 9131 2 1153.612598 577.8118 Lamin-B1 OS=Homo sapiens OX=9606 GN=LMNB1 PE=1 SV=2 9.79 2054.3 - 968544 - - - 3.0001 - 2.092 0.439 - 334.2 1 2 0 0.0035 12 0 0 0 1.94E+08 1.85E+08 - - - 4.2245 0.9997 221125_WJC_METTL3_EV_vs_WT_F04.09135.09135.2 0.00354 18-Oct K.LTDQVMQNPR.V "sp|Q99733|NP1L4_HUMAN,tr|E9PP22|E9PP22_HUMAN,tr|E9PKI2|E9PKI2_HUMAN,tr|C9J1B1|C9J1B1_HUMAN,tr|C9J6D1|C9J6D1_HUMAN,tr|E9PJJ2|E9PJJ2_HUMAN,tr|E9PNW0|E9PNW0_HUMAN,tr|E9PKT8|E9PKT8_HUMAN,tr|E9PS34|E9PS34_HUMAN,tr|C9JZI7|C9JZI7_HUMAN,tr|E9PNJ7|E9PNJ7_HUMAN" 11 1200.5921 0.76 44035 9135 2 1200.590873 601.3033 Nucleosome assembly protein 1-like 4 OS=Homo sapiens OX=9606 GN=NAP1L4 PE=1 SV=1 5.84 2054.9 - 854839 - - - -1.027 - 2.017 0.382 - 265.8 1 2 0 -0.0012 10 0 0 0 8.22E+06 1.09E+07 - - - 3.8205 0.9994 221125_WJC_METTL3_EV_vs_WT_F04.09137.09137.2 0.04 16-Oct R.FQAQLESEK[136.11].N "sp|P82094|TMF1_HUMAN,tr|A0A2R8Y7M0|A0A2R8Y7M0_HUMAN" 2 1086.5437 1.51 44036 9137 2 1086.542869 544.2791 TATA element modulatory factor OS=Homo sapiens OX=9606 GN=TMF1 PE=1 SV=2 4.53 2055.1 - 3.62E+06 - - - -0.7547 - 1.783 0.301 - 266.7 1 2 0 -0.0008 9 0 0 0 1.51E+08 9.98E+07 - - - 2.937 0.9968 221125_WJC_METTL3_EV_vs_WT_F04.09138.09138.2 0.0926 22-Sep R.AGGPTTPLSPTR[166.11].L "sp|P20700|LMNB1_HUMAN,tr|A0A0D9SFY5|A0A0D9SFY5_HUMAN,tr|E9PBF6|E9PBF6_HUMAN,tr|A0A0D9SFE5|A0A0D9SFE5_HUMAN" 4 1163.6174 1.22 44037 9138 2 1163.621163 582.816 Lamin-B1 OS=Homo sapiens OX=9606 GN=LMNB1 PE=1 SV=2 9.79 2055.2 - 1.36E+06 - - - 3.2279 - 1.85 0.298 - 179.7 1 2 0 0.0038 12 0 0 0 2.27E+08 1.87E+08 - - - 2.8595 0.9989 221125_WJC_METTL3_EV_vs_WT_F04.09139.09139.2 0.00908 14-Sep R.NQLQSVYK.M sp|Q9BSM1|PCGF1_HUMAN 1 978.5134 1.14 44038 9139 2 978.512585 490.264 Polycomb group RING finger protein 1 OS=Homo sapiens OX=9606 GN=PCGF1 PE=1 SV=2 8.59 2055.3 - 975482 - - - -0.8789 - 1.278 0.35 - 270.2 1 2 0 -0.0009 8 0 0 0 2.22E+07 1.95E+07 - - - 2.3656 0.9984 221125_WJC_METTL3_EV_vs_WT_F04.09140.09140.2 0.0014 24-Sep R.VPTEPPATSVAAR[166.11].S sp|Q92610|ZN592_HUMAN 1 1304.6964 0.51 44039 9140 2 1304.692847 653.3555 Zinc finger protein 592 OS=Homo sapiens OX=9606 GN=ZNF592 PE=1 SV=2 5.97 2055.4 - 189310 - - - -2.7117 - 1.612 0.394 - 189.2 1 2 0 -0.0035 13 0 0 0 2.42E+06 4.71E+06 - - - 3.1754 0.9998 221125_WJC_METTL3_EV_vs_WT_F04.09143.09143.2 5.03E-06 14-Nov K.HVVFIAQR[166.11].R "sp|P62081|RS7_HUMAN,tr|B5MCP9|B5MCP9_HUMAN,tr|A0A2R8Y623|A0A2R8Y623_HUMAN" 3 978.5639 0.72 44040 9143 2 978.56278 490.2892 40S ribosomal protein S7 OS=Homo sapiens OX=9606 GN=RPS7 PE=1 SV=1 9.76 2055.8 - 1.32E+06 - - - -1.0985 - 1.759 0.515 - 497.2 1 2 0 -0.0011 8 0 0 0 5.97E+08 8.25E+08 - - - 4.5477 0.9382 221125_WJC_METTL3_EV_vs_WT_F04.09144.09144.2 0.00231 14-Jul R.LNTSDFQK.L sp|Q96B36|AKTS1_HUMAN 1 951.4662 1.09 44041 9144 2 951.458751 476.7404 Proline-rich AKT1 substrate 1 OS=Homo sapiens OX=9606 GN=AKT1S1 PE=1 SV=1 5.84 2055.9 - 1.50E+06 - - - -7.788 - 1.376 0.395 - 113.8 1 2 0 -0.0074 8 0 0 0 3.91E+07 3.59E+07 - - - 2.9188 0.9998 221125_WJC_METTL3_EV_vs_WT_F04.09145.09145.2 0.000781 16-Oct K.TGFQAVTGK.R sp|P20042|IF2B_HUMAN 1 907.4763 0.82 44042 9145 2 907.475462 454.7454 Eukaryotic translation initiation factor 2 subunit 2 OS=Homo sapiens OX=9606 GN=EIF2S2 PE=1 SV=2 8.41 2055.9 - 3.66E+06 - - - -0.9576 - 1.82 0.467 - 320 1 2 0 -0.0009 9 0 0 0 8.34E+07 1.02E+08 - - - 4.2225 0.9919 221125_WJC_METTL3_EV_vs_WT_F04.09147.09147.2 0.189 14-May K.ASLC[160.03]ISTK[136.11].K "sp|P09874|PARP1_HUMAN,tr|A0A7I2V3E1|A0A7I2V3E1_HUMAN" 2 886.4674 0.91 44044 9147 2 886.465373 444.241 Poly [ADP-ribose] polymerase 1 OS=Homo sapiens OX=9606 GN=PARP1 PE=1 SV=4 8.27 2056 - 2.01E+06 - - - -2.2336 - 1.358 0.198 - 96.7 1 2 0 -0.002 8 0 0 0 8.46E+07 9.27E+07 - - - 1.4257 0.9987 221125_WJC_METTL3_EV_vs_WT_F04.09148.09148.2 0.000797 14-Jul R.LNTSDFQK[136.11].L sp|Q96B36|AKTS1_HUMAN 1 959.4804 1.1 44045 9148 2 959.477953 480.7475 Proline-rich AKT1 substrate 1 OS=Homo sapiens OX=9606 GN=AKT1S1 PE=1 SV=1 5.84 2056.1 - 1.41E+06 - - - -2.5097 - 1.568 0.378 - 110.4 1 2 0 -0.0024 8 0 0 0 3.94E+07 3.59E+07 - - - 3.1887 0.9998 221125_WJC_METTL3_EV_vs_WT_F04.09150.09150.2 0.0124 16-Aug R.SLQSVAEER[166.11].A "sp|P61313|RL15_HUMAN,tr|A0A2R8YEM3|A0A2R8YEM3_HUMAN,tr|A0A2R8Y738|A0A2R8Y738_HUMAN,tr|E7EQV9|E7EQV9_HUMAN,tr|E7EX53|E7EX53_HUMAN" 5 1027.5174 0.57 44046 9150 2 1027.516926 514.766 60S ribosomal protein L15 OS=Homo sapiens OX=9606 GN=RPL15 PE=1 SV=2 4.53 2056.3 - 4.50E+06 - - - -0.4204 - 1.736 0.461 - 258.9 1 2 0 -0.0004 9 0 0 0 1.51E+08 2.65E+08 - - - 4.0416 0.9997 221125_WJC_METTL3_EV_vs_WT_F04.09153.09153.2 0.00061 18-Oct K.TIEESEETLK.N sp|O95347|SMC2_HUMAN 1 1177.5714 0.84 44048 9153 2 1177.572956 589.793 Structural maintenance of chromosomes protein 2 OS=Homo sapiens OX=9606 GN=SMC2 PE=1 SV=2 4.09 2056.7 - 405812 - - - 1.3095 - 1.873 0.466 - 236.2 1 2 0 0.0015 10 0 0 0 1.80E+07 2.15E+07 - - - 4.2341 0.9997 221125_WJC_METTL3_EV_vs_WT_F04.09158.09158.2 0.000516 18-Oct R.VEVEEDGQLK.S "sp|Q8NHS0|DNJB8_HUMAN,sp|O75190|DNJB6_HUMAN,sp|P25686|DNJB2_HUMAN,tr|C9JXB9|C9JXB9_HUMAN,tr|A0A0J9YX62|A0A0J9YX62_HUMAN,tr|C9J2C4|C9J2C4_HUMAN,tr|C9JRD2|C9JRD2_HUMAN" 7 1144.5612 1.84 44051 9158 2 1144.560044 573.2879 DnaJ homolog subfamily B member 8 OS=Homo sapiens OX=9606 GN=DNAJB8 PE=1 SV=1 4 2057.2 - 2.91E+06 - - - -0.9951 - 1.801 0.442 - 313.8 1 2 0 -0.0011 10 0 0 0 2.48E+08 1.35E+08 - - - 3.9475 0.9992 221125_WJC_METTL3_EV_vs_WT_F04.09159.09159.2 0.00034 14-Oct K.HVVFIAQR.R "sp|P62081|RS7_HUMAN,tr|B5MCP9|B5MCP9_HUMAN,tr|A0A2R8Y623|A0A2R8Y623_HUMAN" 3 968.5556 0.73 44052 9159 2 968.555232 485.2851 40S ribosomal protein S7 OS=Homo sapiens OX=9606 GN=RPS7 PE=1 SV=1 9.76 2057.3 - 2.02E+06 - - - -0.3645 - 1.63 0.278 - 399.9 1 2 0 -0.0004 8 0 0 0 5.97E+08 8.19E+08 - - - 2.5677 0.9998 221125_WJC_METTL3_EV_vs_WT_F04.09160.09160.2 0.000469 18-Oct R.VEVEEDGQLK[136.11].S "sp|Q8NHS0|DNJB8_HUMAN,sp|O75190|DNJB6_HUMAN,sp|P25686|DNJB2_HUMAN,tr|C9JXB9|C9JXB9_HUMAN,tr|A0A0J9YX62|A0A0J9YX62_HUMAN,tr|C9J2C4|C9J2C4_HUMAN,tr|C9JRD2|C9JRD2_HUMAN" 7 1152.5754 1.84 44053 9160 2 1152.574142 577.295 DnaJ homolog subfamily B member 8 OS=Homo sapiens OX=9606 GN=DNAJB8 PE=1 SV=1 4 2057.4 - 2.34E+06 - - - -1.0767 - 2.008 0.5 - 334.1 1 2 0 -0.0012 10 0 0 0 2.48E+08 1.35E+08 - - - 4.6795 0.9992 221125_WJC_METTL3_EV_vs_WT_F04.09162.09162.2 0.102 16-Jul R.LHDSLAIER[166.11].K "sp|Q15005|SPCS2_HUMAN,tr|E9PI68|E9PI68_HUMAN,tr|A0A087WUC6|A0A087WUC6_HUMAN,tr|E9PRB9|E9PRB9_HUMAN,tr|E9PL01|E9PL01_HUMAN" 5 1062.5697 2.93 44055 9162 2 1062.569932 532.2921 Signal peptidase complex subunit 2 OS=Homo sapiens OX=9606 GN=SPCS2 PE=1 SV=3 5.32 2057.6 - 558967 - - - 0.192 - 1.521 0.311 - 253.7 1 2 0 0.0002 9 0 0 0 3.35E+07 1.14E+07 - - - 2.5512 0.9994 221125_WJC_METTL3_EV_vs_WT_F04.09168.09168.2 0.00137 16-Jul K.TGFQAVTGK[136.11].R sp|P20042|IF2B_HUMAN 1 915.4905 0.82 44059 9168 2 915.490865 458.7525 Eukaryotic translation initiation factor 2 subunit 2 OS=Homo sapiens OX=9606 GN=EIF2S2 PE=1 SV=2 8.41 2058.3 - 5.68E+06 - - - 0.3648 - 1.345 0.404 - 152.8 1 2 0 0.0003 9 0 0 0 8.34E+07 1.02E+08 - - - 2.8823 0.9998 221125_WJC_METTL3_EV_vs_WT_F04.09169.09169.2 0.000805 18-Sep R.ITMEYSSSGK[136.11].A "sp|Q12849|GRSF1_HUMAN,tr|H0YAK1|H0YAK1_HUMAN,tr|H0Y8R1|H0Y8R1_HUMAN,tr|F5H5I6|F5H5I6_HUMAN" 4 1109.5154 0.81 44060 9169 2 1109.516482 555.765 G-rich sequence factor 1 OS=Homo sapiens OX=9606 GN=GRSF1 PE=1 SV=3 6 2058.4 - 635056 - - - 0.9518 - 2.082 0.518 - 240.4 1 2 0 0.0011 10 0 0 0 2.52E+07 3.11E+07 - - - 4.9136 0.9934 221125_WJC_METTL3_EV_vs_WT_F04.09172.09172.2 0.078 24-Jul R.VPTEPPATSVAAR.S sp|Q92610|ZN592_HUMAN 1 1294.6881 0.51 44063 9172 2 1294.685827 648.3513 Zinc finger protein 592 OS=Homo sapiens OX=9606 GN=ZNF592 PE=1 SV=2 5.97 2058.8 - 159747 - - - -1.7672 - 1.303 0.219 - 117.7 1 2 0 -0.0023 13 0 0 0 2.42E+06 4.71E+06 - - - 1.3371 0.9813 221125_WJC_METTL3_EV_vs_WT_F04.09173.09173.2 0.00453 24-Sep N.IATVQTSQGLADK[136.11].V "sp|P27708|PYR1_HUMAN,tr|F8VPD4|F8VPD4_HUMAN" 2 1338.7234 0.69 44064 9173 2 1338.721529 670.369 CAD protein OS=Homo sapiens OX=9606 GN=CAD PE=1 SV=3 5.84 2058.9 - 134001 - - - -1.4312 - 2.118 0.411 - 85.2 1 1 0 -0.0019 13 0 0 0 2.35E+06 3.42E+06 - - - 4.0022 0.9998 221125_WJC_METTL3_EV_vs_WT_F04.09176.09176.2 0.000838 18-Oct K.TIEESEETLK[136.11].N sp|O95347|SMC2_HUMAN 1 1185.5856 0.84 44065 9176 2 1185.58638 593.8001 Structural maintenance of chromosomes protein 2 OS=Homo sapiens OX=9606 GN=SMC2 PE=1 SV=2 4.09 2059.3 - 1.21E+06 - - - 0.6461 - 1.706 0.484 - 187.6 1 2 0 0.0008 10 0 0 0 1.83E+07 2.17E+07 - - - 4.1066 0.9995 221125_WJC_METTL3_EV_vs_WT_F04.09178.09178.2 0.00957 16-Sep K.NLSVEDAAR.L sp|P04040|CATA_HUMAN 1 973.4829 75.71 44067 9178 2 973.482578 487.7487 Catalase OS=Homo sapiens OX=9606 GN=CAT PE=1 SV=3 4.37 2059.5 - 1.06E+06 - - - -0.303 - 1.666 0.327 - 296.4 1 2 0 -0.0003 9 0 0 0 2.21E+08 2.91E+06 - - - 2.9328 0.9544 221125_WJC_METTL3_EV_vs_WT_F04.09182.09182.2 3.85 12-May R.TNVPDIR[166.11].V "sp|Q01433|AMPD2_HUMAN,tr|A0A5F9UK94|A0A5F9UK94_HUMAN,tr|A0A804H2H4|A0A804H2H4_HUMAN,tr|H0Y360|H0Y360_HUMAN,tr|H0YF16|H0YF16_HUMAN,tr|A0A804CCZ3|A0A804CCZ3_HUMAN" 6 823.4427 6.63 44071 9182 2 823.441772 412.7286 AMP deaminase 2 OS=Homo sapiens OX=9606 GN=AMPD2 PE=1 SV=2 5.5 2060.1 - 310570 - - - -1.1719 - 1.115 0.054 - 133.4 1 2 0 -0.001 7 0 0 0 2.24E+08 3.38E+07 - - - -0.2155 0.9985 221125_WJC_METTL3_EV_vs_WT_F04.09184.09184.2 0.00128 22-Oct K.VVETELQEGATK[136.11].Q sp|Q8NFC6|BD1L1_HUMAN 1 1310.6809 0.52 44073 9184 2 1310.675853 656.3477 Biorientation of chromosomes in cell division protein 1-like 1 OS=Homo sapiens OX=9606 GN=BOD1L1 PE=1 SV=2 4.25 2060.3 - 206435 - - - -3.8591 - 2.169 0.433 - 248.8 1 2 0 -0.0051 12 0 0 0 1.88E+06 3.65E+06 - - - 4.2748 0.9973 221125_WJC_METTL3_EV_vs_WT_F04.09187.09187.2 0.0947 14-Jun K.ILEVHVDK[136.11].G sp|O60884|DNJA2_HUMAN 1 959.5531 0.36 44074 9187 2 959.552655 480.7838 DnaJ homolog subfamily A member 2 OS=Homo sapiens OX=9606 GN=DNAJA2 PE=1 SV=1 5.32 2060.8 - 2.15E+06 - - - -0.4971 - 1.311 0.232 - 65.2 1 2 0 -0.0005 8 0 0 0 2.03E+07 5.71E+07 - - - 1.5711 0.9999 221125_WJC_METTL3_EV_vs_WT_F04.09188.09188.2 1.26E-05 18-Oct R.ITMEYSSSGK.A "sp|Q12849|GRSF1_HUMAN,tr|H0YAK1|H0YAK1_HUMAN,tr|H0Y8R1|H0Y8R1_HUMAN,tr|F5H5I6|F5H5I6_HUMAN" 4 1101.5012 0.81 44075 9188 2 1101.500881 551.7579 G-rich sequence factor 1 OS=Homo sapiens OX=9606 GN=GRSF1 PE=1 SV=3 6 2060.9 - 1.11E+06 - - - -0.3132 - 2.044 0.538 - 338.8 1 2 0 -0.0003 10 0 0 0 2.52E+07 3.11E+07 - - - 5.0101 0.9885 221125_WJC_METTL3_EV_vs_WT_F04.09191.09191.2 1.05 12-Jul K.DQGINIR.Q sp|Q14677|EPN4_HUMAN 1 814.4297 1.61 44078 9191 2 814.429686 408.2221 Clathrin interactor 1 OS=Homo sapiens OX=9606 GN=CLINT1 PE=1 SV=1 5.84 2061.2 - 563971 - - - -0.0368 - 1.591 0.001 - 301.4 1 2 0 0 7 0 0 0 6.21E+08 3.86E+08 - - - 0.5197 0.9998 221125_WJC_METTL3_EV_vs_WT_F04.09192.09192.2 0.000364 20-Nov K.TLNMTTSPEEK[136.11].R sp|P49915|GUAA_HUMAN 1 1257.6002 0.56 44079 9192 2 1257.600721 629.8074 GMP synthase [glutamine-hydrolyzing] OS=Homo sapiens OX=9606 GN=GMPS PE=1 SV=1 4.53 2061.3 - 510324 - - - 0.4 - 2.097 0.435 - 332.1 1 2 0 0.0005 11 0 0 0 1.02E+07 1.83E+07 - - - 4.257 0.9979 221125_WJC_METTL3_EV_vs_WT_F04.09197.09197.3 0.0863 Dec-36 R.LSSEVEALRR.Q sp|P15924|DESP_HUMAN 1 1158.6357 18.36 44082 9197 3 1158.634178 387.2192 Desmoplakin OS=Homo sapiens OX=9606 GN=DSP PE=1 SV=3 6.14 2062 - 3.86E+06 - - - -1.3015 - 1.951 0.216 - 204.8 1 2 0 -0.0015 10 0 0 0 4.26E+07 2.32E+06 - - - 2.8996 0.9997 221125_WJC_METTL3_EV_vs_WT_F04.09198.09198.2 0.000128 14-Jul R.YFDPANGK[136.11].F sp|P13639|EF2_HUMAN 1 918.4327 0.43 44083 9198 2 918.432566 460.2236 Elongation factor 2 OS=Homo sapiens OX=9606 GN=EEF2 PE=1 SV=4 5.83 2062.1 - 1.87E+06 - - - -0.1263 - 1.478 0.43 - 136.3 1 2 0 -0.0001 8 0 0 0 2.47E+07 5.76E+07 - - - 3.3952 0.9998 221125_WJC_METTL3_EV_vs_WT_F04.09201.09201.2 4.38E-05 18-Oct R.GEALSNSVYK.G sp|Q8N2G6|ZCH24_HUMAN 1 1066.5295 1.33 44086 9201 2 1066.530081 534.272 Zinc finger CCHC domain-containing protein 24 OS=Homo sapiens OX=9606 GN=ZCCHC24 PE=1 SV=1 6 2062.3 - 598007 - - - 0.5551 - 1.986 0.484 - 393 1 2 0 0.0006 10 0 0 0 4.91E+07 3.70E+07 - - - 4.5308 1 221125_WJC_METTL3_EV_vs_WT_F04.09202.09202.2 8.06E-08 16/26 R.AEEEAAVVAASSSK.K "sp|O15417|TNC18_HUMAN,tr|H9KVB4|H9KVB4_HUMAN" 2 1347.6518 2.24 44087 9202 2 1347.650057 674.8332 Trinucleotide repeat-containing gene 18 protein OS=Homo sapiens OX=9606 GN=TNRC18 PE=1 SV=3 4.25 2062.5 - 276877 - - - -1.2852 - 3.064 0.601 - 866.1 1 2 0 -0.0017 14 0 0 0 5.73E+06 2.56E+06 - - - 6.2893 0.9997 221125_WJC_METTL3_EV_vs_WT_F04.09203.09203.2 4.65E-05 26-Oct R.AEEEAAVVAASSSK[136.11].K "sp|O15417|TNC18_HUMAN,tr|H9KVB4|H9KVB4_HUMAN" 2 1355.666 2.24 44088 9203 2 1355.663394 678.8403 Trinucleotide repeat-containing gene 18 protein OS=Homo sapiens OX=9606 GN=TNRC18 PE=1 SV=3 4.25 2062.6 - 168578 - - - -1.9142 - 2.222 0.487 - 316.8 1 2 0 -0.0026 14 0 0 0 5.73E+06 2.56E+06 - - - 4.6407 0.9427 221125_WJC_METTL3_EV_vs_WT_F04.09205.09205.2 0.0576 12-Jul L.LEVHVDK[136.11].G sp|O60884|DNJA2_HUMAN 1 846.4691 0.46 44089 9205 2 846.46846 424.2418 DnaJ homolog subfamily A member 2 OS=Homo sapiens OX=9606 GN=DNAJA2 PE=1 SV=1 5.32 2062.8 - 6.61E+06 - - - -0.7183 - 1.428 0.306 - 157.2 1 1 0 -0.0006 7 0 0 0 4.53E+07 9.75E+07 - - - 2.4298 0.9979 221125_WJC_METTL3_EV_vs_WT_F04.09209.09209.2 0.547 16-Aug K.QLLPSGNGR.S "sp|Q9H2P0|ADNP_HUMAN,tr|A0A2R8Y6X0|A0A2R8Y6X0_HUMAN,tr|A0A669KBJ7|A0A669KBJ7_HUMAN" 3 940.509 0.82 44092 9209 2 940.509038 471.2618 Activity-dependent neuroprotector homeobox protein OS=Homo sapiens OX=9606 GN=ADNP PE=1 SV=1 9.75 2063.3 - 698734 - - - 0.0096 - 1.67 0.184 - 218.6 2 2 0 0 9 0 0 0 1.70E+07 2.08E+07 - - - 1.7492 0.9995 221125_WJC_METTL3_EV_vs_WT_F04.09212.09212.2 5.37E-05 20-Sep K.SSPVVNDGVVR[166.11].L "sp|Q12849|GRSF1_HUMAN,tr|H0YAK1|H0YAK1_HUMAN,tr|H0Y8R1|H0Y8R1_HUMAN,tr|F5H5I6|F5H5I6_HUMAN,tr|H0YAM1|H0YAM1_HUMAN" 5 1137.6018 0.75 44094 9212 2 1137.604713 569.8082 G-rich sequence factor 1 OS=Homo sapiens OX=9606 GN=GRSF1 PE=1 SV=3 5.55 2063.6 - 1.08E+06 - - - 2.5984 - 1.843 0.513 - 272.9 1 2 0 0.003 11 0 0 0 4.20E+08 5.61E+08 - - - 4.4831 0.9982 221125_WJC_METTL3_EV_vs_WT_F04.09216.09216.2 0.0976 14-Aug K.GDDLQAIK[136.11].Q "sp|P0DMR1|HNRC4_HUMAN,sp|P07910|HNRPC_HUMAN,sp|O60812|HNRC1_HUMAN,sp|B2RXH8|HNRC2_HUMAN,sp|B7ZW38|HNRC3_HUMAN,tr|B4DY08|B4DY08_HUMAN,tr|G3V5V7|G3V5V7_HUMAN,tr|B2R5W2|B2R5W2_HUMAN,tr|G3V4C1|G3V4C1_HUMAN,tr|A0A0G2JPF8|A0A0G2JPF8_HUMAN,tr|A0A0G2JNQ3|A0A0G2JNQ3_HUMAN,tr|G3V576|G3V576_HUMAN,tr|G3V2D6|G3V2D6_HUMAN,tr|G3V4W0|G3V4W0_HUMAN,tr|G3V2Q1|G3V2Q1_HUMAN" 15 866.4589 4.48 44097 9216 2 866.459325 434.2367 Heterogeneous nuclear ribonucleoprotein C-like 4 OS=Homo sapiens OX=9606 GN=HNRNPCL4 PE=3 SV=1 4.21 2064 - 773998 - - - 0.494 - 1.513 0.226 - 229.1 1 2 0 0.0004 8 0 0 0 8.56E+07 1.91E+07 - - - 1.959 0.9998 221125_WJC_METTL3_EV_vs_WT_F04.09222.09222.2 4.48E-05 20-Sep R.LSPENNQVLTK.K "sp|Q16514|TAF12_HUMAN,tr|A0A804HLG9|A0A804HLG9_HUMAN" 2 1241.6616 1.7 44101 9222 2 1241.662079 621.8381 Transcription initiation factor TFIID subunit 12 OS=Homo sapiens OX=9606 GN=TAF12 PE=1 SV=1 6 2064.8 - 810103 - - - 0.4132 - 1.752 0.498 - 278 1 2 0 0.0005 11 0 0 0 1.30E+08 7.67E+07 - - - 4.2361 0.9993 221125_WJC_METTL3_EV_vs_WT_F04.09223.09223.2 0.0974 14-Sep K.EQTEQILR[166.11].D "sp|P22102|PUR2_HUMAN,tr|A0A140TA71|A0A140TA71_HUMAN" 2 1025.5381 0.85 44102 9223 2 1025.538035 513.7763 Trifunctional purine biosynthetic protein adenosine-3 OS=Homo sapiens OX=9606 GN=GART PE=1 SV=1 4.53 2064.9 - 803390 - - - -0.0575 - 1.768 0.258 - 554.5 1 2 0 -0.0001 8 0 0 0 3.43E+07 4.03E+07 - - - 2.6652 0.9986 221125_WJC_METTL3_EV_vs_WT_F04.09226.09226.2 0.209 14-Jun K.ASLC[160.03]ISTK.K "sp|P09874|PARP1_HUMAN,tr|A0A7I2V3E1|A0A7I2V3E1_HUMAN" 2 878.4532 0.91 44104 9226 2 878.452907 440.2339 Poly [ADP-ribose] polymerase 1 OS=Homo sapiens OX=9606 GN=PARP1 PE=1 SV=4 8.27 2065.3 - 1.85E+06 - - - -0.28 - 1.515 0.243 - 123 1 2 0 -0.0002 8 0 0 0 8.47E+07 9.27E+07 - - - 2.0886 0.9994 221125_WJC_METTL3_EV_vs_WT_F04.09227.09227.2 0.0824 14-Aug R.FSELTAEK.L "sp|P48643|TCPE_HUMAN,tr|E9PCA1|E9PCA1_HUMAN,tr|B7ZAR1|B7ZAR1_HUMAN,tr|E7ENZ3|E7ENZ3_HUMAN" 4 923.46 0.62 44105 9227 2 923.460221 462.7373 T-complex protein 1 subunit epsilon OS=Homo sapiens OX=9606 GN=CCT5 PE=1 SV=1 4.53 2065.3 - 1.51E+06 - - - 0.2252 - 1.832 0.278 - 161.9 1 2 0 0.0002 8 0 0 0 2.51E+07 4.04E+07 - - - 2.9201 0.9973 221125_WJC_METTL3_EV_vs_WT_F04.09228.09228.2 0.244 14-Aug K.EELAYLKK.N "sp|Q04695|K1C17_HUMAN,sp|P13645|K1C10_HUMAN,sp|P02533|K1C14_HUMAN,sp|Q7Z3Y8|K1C27_HUMAN,sp|P08727|K1C19_HUMAN,sp|P19012|K1C15_HUMAN,tr|K7EPJ9|K7EPJ9_HUMAN,tr|K7ESE1|K7ESE1_HUMAN,tr|C9JM50|C9JM50_HUMAN,tr|A0A1B0GVI3|A0A1B0GVI3_HUMAN,tr|C9JTG5|C9JTG5_HUMAN,tr|F5GWP8|F5GWP8_HUMAN,tr|K7EMS3|K7EMS3_HUMAN,tr|A8MT21|A8MT21_HUMAN" 14 992.5542 22.99 44106 9228 2 992.554939 497.2844 "Keratin, type I cytoskeletal 17 OS=Homo sapiens OX=9606 GN=KRT17 PE=1 SV=2" 6.24 2065.4 - 1.86E+06 - - - 0.6972 - 1.372 0.228 - 245.7 1 2 0 0.0007 8 0 0 0 7.54E+07 3.28E+06 - - - 1.6786 0.9918 221125_WJC_METTL3_EV_vs_WT_F04.09232.09232.2 0.00512 14-Aug K.EQTEQILR.D "sp|P22102|PUR2_HUMAN,tr|A0A140TA71|A0A140TA71_HUMAN" 2 1015.5298 0.8 44109 9232 2 1015.524796 508.7722 Trifunctional purine biosynthetic protein adenosine-3 OS=Homo sapiens OX=9606 GN=GART PE=1 SV=1 4.53 2065.9 - 1.36E+06 - - - -4.9511 - 1.762 0.324 - 285.4 1 2 0 -0.005 8 0 0 0 3.58E+07 4.50E+07 - - - 3.1409 1 221125_WJC_METTL3_EV_vs_WT_F04.09235.09235.2 5.09E-06 20-Oct K.AFDTAGNGYC[160.03]R.S "sp|P49327|FAS_HUMAN,tr|A0A0U1RQF0|A0A0U1RQF0_HUMAN" 2 1230.5088 0.75 44112 9235 2 1230.50833 616.2617 Fatty acid synthase OS=Homo sapiens OX=9606 GN=FASN PE=1 SV=3 5.87 2066.2 - 443547 - - - -0.3584 - 2.264 0.619 - 321.4 1 2 0 -0.0004 11 0 0 0 2.09E+07 2.81E+07 - - - 5.8233 0.9994 221125_WJC_METTL3_EV_vs_WT_F04.09236.09236.2 0.196 16-Aug K.IDVGEAEPR.T "sp|P54577|SYYC_HUMAN,tr|A0A6Q8PFX2|A0A6Q8PFX2_HUMAN" 2 984.4876 0.82 44113 9236 2 984.488068 493.2511 "Tyrosine--tRNA ligase, cytoplasmic OS=Homo sapiens OX=9606 GN=YARS1 PE=1 SV=4" 4.14 2066.4 - 370683 - - - 0.451 - 1.862 0.279 - 198.7 1 2 0 0.0004 9 0 0 0 8.23E+06 1.00E+07 - - - 2.9 0.9993 221125_WJC_METTL3_EV_vs_WT_F04.09239.09239.2 0.00147 14-Aug R.DYDDMSPR[166.11].R "sp|P61978|HNRPK_HUMAN,tr|Q5T6W2|Q5T6W2_HUMAN" 2 1007.3894 1.27 44114 9239 2 1007.389657 504.702 Heterogeneous nuclear ribonucleoprotein K OS=Homo sapiens OX=9606 GN=HNRNPK PE=1 SV=1 3.93 2066.8 - 4.17E+06 - - - 0.275 - 1.482 0.333 - 221.4 1 2 0 0.0003 8 0 0 0 2.07E+08 1.63E+08 - - - 2.6869 0.9949 221125_WJC_METTL3_EV_vs_WT_F04.09240.09240.2 4.69 12-Jul K.KLQDLVR.E "sp|Q16514|TAF12_HUMAN,sp|O94759|TRPM2_HUMAN,tr|E9PGK7|E9PGK7_HUMAN,tr|A0A804HLG9|A0A804HLG9_HUMAN" 4 870.5287 19.65 44115 9240 2 870.52819 436.2716 Transcription initiation factor TFIID subunit 12 OS=Homo sapiens OX=9606 GN=TAF12 PE=1 SV=1 8.75 2066.9 - 520750 - - - -0.587 - 1.51 0.104 - 243 1 2 0 -0.0005 7 0 0 0 3.17E+08 1.61E+07 - - - 1.1148 0.9994 221125_WJC_METTL3_EV_vs_WT_F04.09241.09241.2 3.42E-05 14-Aug R.DYDDMSPR.R "sp|P61978|HNRPK_HUMAN,tr|Q5T6W2|Q5T6W2_HUMAN" 2 997.3811 1.27 44116 9241 2 997.381329 499.6978 Heterogeneous nuclear ribonucleoprotein K OS=Homo sapiens OX=9606 GN=HNRNPK PE=1 SV=1 3.93 2066.9 - 5.95E+06 - - - 0.2196 - 1.702 0.29 - 232.4 1 2 0 0.0002 8 0 0 0 2.07E+08 1.63E+08 - - - 2.7868 0.9971 221125_WJC_METTL3_EV_vs_WT_F04.09243.09243.2 0.612 12-Jun K.K[136.11]LQDLVR[166.11].E "sp|Q16514|TAF12_HUMAN,sp|O94759|TRPM2_HUMAN,tr|E9PGK7|E9PGK7_HUMAN,tr|A0A804HLG9|A0A804HLG9_HUMAN" 4 888.5512 18.59 44118 9243 2 888.550592 445.2829 Transcription initiation factor TFIID subunit 12 OS=Homo sapiens OX=9606 GN=TAF12 PE=1 SV=1 8.75 2067.2 - 548889 - - - -0.6516 - 1.501 0.165 - 150.7 1 2 0 -0.0006 7 0 0 0 3.00E+08 1.61E+07 - - - 1.5464 0.9258 221125_WJC_METTL3_EV_vs_WT_F04.09247.09247.2 1.24 24-Jul R.GGAAGGGGGWTSR[166.11].A sp|P29376|LTK_HUMAN 1 1099.5034 0.001 44120 9247 2 1099.504945 550.759 Leukocyte tyrosine kinase receptor OS=Homo sapiens OX=9606 GN=LTK PE=1 SV=3 9.75 2067.7 - 685273 - - - 1.3697 - 1.218 0.035 - 107.6 3 2 0 0.0015 13 0 0 0 0.00E+00 3.85E+07 - - - -0.4079 0.9951 221125_WJC_METTL3_EV_vs_WT_F04.09249.09249.2 0.213 16-Aug R.DTQEVPLEK.A "sp|Q9Y5A9|YTHD2_HUMAN,sp|Q9BYJ9|YTHD1_HUMAN,sp|Q7Z739|YTHD3_HUMAN,tr|A0A087X0Q1|A0A087X0Q1_HUMAN,tr|A0A024R7W5|A0A024R7W5_HUMAN,tr|A0A087WY31|A0A087WY31_HUMAN" 6 1057.5292 1.54 44122 9249 2 1057.532093 529.7719 YTH domain-containing family protein 2 OS=Homo sapiens OX=9606 GN=YTHDF2 PE=1 SV=2 4.14 2067.9 - 2.41E+06 - - - 2.7782 - 1.647 0.23 - 258.1 1 2 0 0.0029 9 0 0 0 2.83E+09 1.84E+09 - - - 2.1824 0.9759 221125_WJC_METTL3_EV_vs_WT_F04.09250.09250.2 0.575 12-Jun R.INIPPQR.G "sp|Q13283|G3BP1_HUMAN,tr|A0A7I2V5M7|A0A7I2V5M7_HUMAN,tr|A0A7P0P2U7|A0A7P0P2U7_HUMAN,tr|A0A7I2YQU8|A0A7I2YQU8_HUMAN,tr|A0A7I2V548|A0A7I2V548_HUMAN,tr|A0A7I2V565|A0A7I2V565_HUMAN,tr|A0A7I2YQN9|A0A7I2YQN9_HUMAN" 7 836.4868 1.72 44123 9250 2 836.486722 419.2507 Ras GTPase-activating protein-binding protein 1 OS=Homo sapiens OX=9606 GN=G3BP1 PE=1 SV=1 9.75 2068 - 1.02E+06 - - - -0.1375 - 1.367 0 - 148.8 1 2 0 -0.0001 7 0 0 0 2.83E+07 1.65E+07 - - - 0.0315 0.9735 221125_WJC_METTL3_EV_vs_WT_F04.09252.09252.2 0.0105 12-Aug L.PR[166.11]PPGEK[136.11].G sp|Q9NY12|GAR1_HUMAN 1 797.4515 3.51 44124 9252 2 797.451021 399.733 H\ACA ribonucleoprotein complex subunit 1 OS=Homo sapiens OX=9606 GN=GAR1 PE=1 SV=1 9.18 2068.2 - 2.10E+06 - - - -0.5467 - 1.732 0.322 - 330 1 1 0 -0.0004 7 0 0 0 3.26E+08 9.29E+07 - - - 3.1596 0.9998 221125_WJC_METTL3_EV_vs_WT_F04.09254.09254.2 0.00593 18-Dec K.LGSLVENNER[166.11].V "sp|Q99613|EIF3C_HUMAN,sp|B5ME19|EIFCL_HUMAN" 2 1139.581 0.84 44125 9254 2 1139.581322 570.7978 Eukaryotic translation initiation factor 3 subunit C OS=Homo sapiens OX=9606 GN=EIF3C PE=1 SV=1 4.53 2068.4 - 1.44E+06 - - - 0.2641 - 2.452 0.342 - 658.1 1 2 0 0.0003 10 0 0 0 2.85E+07 3.41E+07 - - - 4.0704 0.9685 221125_WJC_METTL3_EV_vs_WT_F04.09255.09255.2 1.05 12-Jun R.SWQPVSR[166.11].L sp|Q8WUF5|IASPP_HUMAN 1 868.4431 4.05 44126 9255 2 868.441431 435.2288 RelA-associated inhibitor OS=Homo sapiens OX=9606 GN=PPP1R13L PE=1 SV=4 9.47 2068.5 - 756232 - - - -1.8884 - 1.068 0.143 - 141.3 1 2 0 -0.0016 7 0 0 0 8.14E+07 2.01E+07 - - - 0.3051 0.9976 221125_WJC_METTL3_EV_vs_WT_F04.09256.09256.2 1.97 18-Aug K.LNEQQSVLQR.L "sp|Q14683|SMC1A_HUMAN,tr|G8JLG1|G8JLG1_HUMAN,tr|A0A6Q8PHC3|A0A6Q8PHC3_HUMAN,tr|V9GY57|V9GY57_HUMAN" 4 1213.6415 0.99 44127 9256 2 1213.640892 607.828 Structural maintenance of chromosomes protein 1A OS=Homo sapiens OX=9606 GN=SMC1A PE=1 SV=2 6 2068.7 - 348273 - - - -0.5001 - 1.879 0.117 - 164.4 1 2 0 -0.0006 10 0 0 0 1.06E+08 1.07E+08 - - - 1.6656 0.9999 221125_WJC_METTL3_EV_vs_WT_F04.09261.09261.2 0.00676 14/18 R.YPDGIISK[136.11]PK[136.11].N sp|Q86U44|MTA70_HUMAN 1 1132.6463 0 44130 9261 2 1132.645824 567.3304 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 8.5 2069.3 - 7.55E+06 - - - -0.4291 - 2.49 0.525 - 749.5 1 2 0 -0.0005 10 0 0 0 1.37E+07 1.56E+10 - - - 5.465 0.9997 221125_WJC_METTL3_EV_vs_WT_F04.09263.09263.2 0.000166 20-Oct R.AAPGAEFAPNK.R "sp|Q15233|NONO_HUMAN,tr|A0A7I2V535|A0A7I2V535_HUMAN,tr|A0A7I2V4K9|A0A7I2V4K9_HUMAN,tr|A0A7I2V4J2|A0A7I2V4J2_HUMAN,tr|A0A7I2V5Y7|A0A7I2V5Y7_HUMAN" 5 1071.5349 0.62 44132 9263 2 1071.532503 536.7747 Non-POU domain-containing octamer-binding protein OS=Homo sapiens OX=9606 GN=NONO PE=1 SV=4 6.05 2069.4 - 2.67E+06 - - - -2.2454 - 2.064 0.506 - 408.3 1 2 0 -0.0024 11 0 0 0 6.98E+07 1.13E+08 - - - 4.7379 0.9965 221125_WJC_METTL3_EV_vs_WT_F04.09264.09264.3 0.0639 Nov-36 R.IGAEVYHNLK[136.11].N "sp|P06733|ENOA_HUMAN,tr|A0A2R8Y6G6|A0A2R8Y6G6_HUMAN,tr|K7EM90|K7EM90_HUMAN" 3 1150.6226 1.49 44133 9264 3 1150.622163 384.5481 Alpha-enolase OS=Homo sapiens OX=9606 GN=ENO1 PE=1 SV=2 6.75 2069.5 - 1.68E+06 - - - -0.3867 - 1.612 0.227 - 97 1 2 0 -0.0004 10 0 0 0 9.59E+08 6.44E+08 - - - 2.4651 0.9995 221125_WJC_METTL3_EV_vs_WT_F04.09268.09268.2 0.00746 16-Aug R.DTQEVPLEK[136.11].A "sp|Q9Y5A9|YTHD2_HUMAN,sp|Q9BYJ9|YTHD1_HUMAN,sp|Q7Z739|YTHD3_HUMAN,tr|A0A087X0Q1|A0A087X0Q1_HUMAN,tr|A0A024R7W5|A0A024R7W5_HUMAN,tr|A0A087WY31|A0A087WY31_HUMAN" 6 1065.5434 1.54 44135 9268 2 1065.543137 533.779 YTH domain-containing family protein 2 OS=Homo sapiens OX=9606 GN=YTHDF2 PE=1 SV=2 4.14 2070 - 5.80E+06 - - - -0.2046 - 1.57 0.35 - 256.4 1 2 0 -0.0002 9 0 0 0 2.83E+09 1.84E+09 - - - 2.931 0.9999 221125_WJC_METTL3_EV_vs_WT_F04.09269.09269.2 0.0105 18-Dec K.LNEQQSVLQR[166.11].L "sp|Q14683|SMC1A_HUMAN,tr|G8JLG1|G8JLG1_HUMAN,tr|A0A6Q8PHC3|A0A6Q8PHC3_HUMAN,tr|V9GY57|V9GY57_HUMAN" 4 1223.6498 0.99 44136 9269 2 1223.649305 612.8322 Structural maintenance of chromosomes protein 1A OS=Homo sapiens OX=9606 GN=SMC1A PE=1 SV=2 6 2070.2 - 765684 - - - -0.3792 - 2.583 0.417 - 713.2 1 2 0 -0.0005 10 0 0 0 1.06E+08 1.07E+08 - - - 4.7696 0.9867 221125_WJC_METTL3_EV_vs_WT_F04.09270.09270.2 0.0225 12-Jul R.EIAQDFK.T "sp|Q16695|H31T_HUMAN,sp|P84243|H33_HUMAN,sp|Q71DI3|H32_HUMAN,sp|P68431|H31_HUMAN,tr|B4DEB1|B4DEB1_HUMAN,tr|K7EK07|K7EK07_HUMAN,tr|K7ES00|K7ES00_HUMAN,tr|K7EMV3|K7EMV3_HUMAN,tr|A0A590UJJ6|A0A590UJJ6_HUMAN" 9 849.4232 0.78 44137 9270 2 849.422731 425.7189 Histone H3.1t OS=Homo sapiens OX=9606 GN=H3-4 PE=1 SV=3 4.37 2070.3 - 793027 - - - -0.591 - 1.257 0.094 - 205.5 1 2 0 -0.0005 7 0 0 0 7.73E+07 9.94E+07 - - - 0.4599 0.9996 221125_WJC_METTL3_EV_vs_WT_F04.09272.09272.2 0.00775 14-Sep R.SPDTILQK.D sp|P20042|IF2B_HUMAN 1 900.4916 0.91 44139 9272 2 900.491346 451.2531 Eukaryotic translation initiation factor 2 subunit 2 OS=Homo sapiens OX=9606 GN=EIF2S2 PE=1 SV=2 5.55 2070.6 - 377699 - - - -0.3343 - 1.663 0.378 - 304 1 2 0 -0.0003 8 0 0 0 2.84E+07 3.11E+07 - - - 3.3668 0.9999 221125_WJC_METTL3_EV_vs_WT_F04.09277.09277.2 6.96E-08 22-Nov K.LVNANGEAVYC[160.03]K.F sp|P04040|CATA_HUMAN 1 1336.6445 999 44141 9277 2 1336.643919 669.3295 Catalase OS=Homo sapiens OX=9606 GN=CAT PE=1 SV=3 5.99 2071.3 - 182374 - - - -0.4616 - 2.003 0.577 - 247.9 1 2 0 -0.0006 12 0 0 0 1.46E+08 0.00E+00 - - - 5.1303 0.9917 221125_WJC_METTL3_EV_vs_WT_F04.09278.09278.2 0.199 20-Jul R.ALLDSSENC[160.03]DR[166.11].L sp|Q5VT52|RPRD2_HUMAN 1 1288.5593 2.08 44142 9278 2 1288.558763 645.2869 Regulation of nuclear pre-mRNA domain-containing protein 2 OS=Homo sapiens OX=9606 GN=RPRD2 PE=1 SV=1 4.03 2071.4 - 88833.5 - - - -0.4167 - 1.127 0.188 - 168.7 1 2 0 -0.0005 11 0 0 0 6.98E+06 3.36E+06 - - - 0.7528 0.9959 221125_WJC_METTL3_EV_vs_WT_F04.09279.09279.2 0.0485 16-Aug K.YGINTDPPK[136.11].- sp|Q9Y3B4|SF3B6_HUMAN 1 1011.5117 1.53 44143 9279 2 1011.510232 506.7631 Splicing factor 3B subunit 6 OS=Homo sapiens OX=9606 GN=SF3B6 PE=1 SV=1 5.83 2071.5 - 1.63E+06 - - - -1.4127 - 1.379 0.211 - 207.4 1 2 0 -0.0014 9 0 0 0 1.84E+08 1.21E+08 - - - 1.5287 0.9969 221125_WJC_METTL3_EV_vs_WT_F04.09282.09282.2 0.179 20-Jul R.ALLDSSENC[160.03]DR.L sp|Q5VT52|RPRD2_HUMAN 1 1278.551 2.08 44144 9282 2 1278.553999 640.2828 Regulation of nuclear pre-mRNA domain-containing protein 2 OS=Homo sapiens OX=9606 GN=RPRD2 PE=1 SV=1 4.03 2071.9 - 254698 - - - 2.3222 - 1.424 0.312 - 167.2 1 2 0 0.003 11 0 0 0 6.98E+06 3.36E+06 - - - 2.3007 0.9966 221125_WJC_METTL3_EV_vs_WT_F04.09285.09285.3 4.71E-06 13/40 Y.LLSSAYVDSHK[136.11].W "sp|Q92552|RT27_HUMAN,tr|E5RJ73|E5RJ73_HUMAN" 2 1226.6387 8.1 44146 9285 3 1226.63745 409.8868 "28S ribosomal protein S27, mitochondrial OS=Homo sapiens OX=9606 GN=MRPS27 PE=1 SV=3" 6.74 2072.2 - 2.97E+06 - - - -0.9799 - 2.32 0.491 - 188.2 1 1 0 -0.0012 11 0 0 0 6.16E+08 7.61E+07 - - - 6.4046 0.9999 221125_WJC_METTL3_EV_vs_WT_F04.09287.09287.2 0.0214 13/18 R.YPDGIISK[136.11]PK.N sp|Q86U44|MTA70_HUMAN 1 1124.6321 - 44148 9287 2 1124.632537 563.3233 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 8.5 2072.4 - 874446 - - - 0.3797 - 2.226 0.519 - 587.3 1 2 0 0.0004 10 0 0 0 - - - - - 5.1078 0.8434 221125_WJC_METTL3_EV_vs_WT_F04.09289.09289.2 1.05 12-Aug L.PRPPGEK.G sp|Q9NY12|GAR1_HUMAN 1 779.429 1.63 44149 9289 2 779.428513 390.7218 H\ACA ribonucleoprotein complex subunit 1 OS=Homo sapiens OX=9606 GN=GAR1 PE=1 SV=1 9.18 2072.6 - 1.51E+06 - - - -0.6081 - 1.555 0.143 - 318.2 1 1 0 -0.0005 7 0 0 0 8.62E+07 5.30E+07 - - - 1.4959 0.9744 221125_WJC_METTL3_EV_vs_WT_F04.09291.09291.2 0.00014 16-Dec L.GAEVYHNLK[136.11].N "sp|P06733|ENOA_HUMAN,tr|A0A2R8Y6G6|A0A2R8Y6G6_HUMAN,tr|K7EM90|K7EM90_HUMAN" 3 1037.5385 1.82 44150 9291 2 1037.540692 519.7765 Alpha-enolase OS=Homo sapiens OX=9606 GN=ENO1 PE=1 SV=2 6.75 2072.8 - 1.17E+06 - - - 2.0703 - 2.186 0.396 - 759 1 1 0 0.0021 9 0 0 0 1.10E+08 6.05E+07 - - - 4.2278 0.8612 221125_WJC_METTL3_EV_vs_WT_F04.09292.09292.2 0.0377 18-Sep R.SLPSQQMVNR.L "sp|Q9H2P0|ADNP_HUMAN,tr|A0A2R8Y6X0|A0A2R8Y6X0_HUMAN,tr|A0A669KBJ7|A0A669KBJ7_HUMAN" 3 1158.5815 1 44151 9292 2 1158.572566 580.298 Activity-dependent neuroprotector homeobox protein OS=Homo sapiens OX=9606 GN=ADNP PE=1 SV=1 9.47 2072.9 - 561876 - - - -7.7474 - 1.569 0.243 - 336.5 1 2 0 -0.009 10 0 0 0 1.84E+07 1.84E+07 - - - 2.0903 0.9996 221125_WJC_METTL3_EV_vs_WT_F04.09293.09293.2 0.000391 18-Oct R.IGAEVYHNLK.N "sp|P06733|ENOA_HUMAN,tr|A0A2R8Y6G6|A0A2R8Y6G6_HUMAN,tr|K7EM90|K7EM90_HUMAN" 3 1142.6084 1.6 44152 9293 2 1142.610062 572.3115 Alpha-enolase OS=Homo sapiens OX=9606 GN=ENO1 PE=1 SV=2 6.75 2073 - 2.64E+06 - - - 1.4476 - 2.385 0.309 - 259.7 1 2 0 0.0017 10 0 0 0 1.97E+08 1.23E+08 - - - 3.749 0.9999 221125_WJC_METTL3_EV_vs_WT_F04.09294.09294.2 0.00387 13/18 R.IGAEVYHNLK[136.11].N "sp|P06733|ENOA_HUMAN,tr|A0A2R8Y6G6|A0A2R8Y6G6_HUMAN,tr|K7EM90|K7EM90_HUMAN" 3 1150.6226 1.6 44153 9294 2 1150.623387 576.3186 Alpha-enolase OS=Homo sapiens OX=9606 GN=ENO1 PE=1 SV=2 6.75 2073 - 2.21E+06 - - - 0.677 - 2.564 0.421 - 579.6 1 2 0 0.0008 10 0 0 0 1.97E+08 1.23E+08 - - - 4.7785 0.9987 221125_WJC_METTL3_EV_vs_WT_F04.09298.09298.2 0.00389 16-Aug K.EQAVQVPVK.G "sp|Q5JSZ5|PRC2B_HUMAN,tr|A0A804HKC3|A0A804HKC3_HUMAN,tr|A0A804HJR4|A0A804HJR4_HUMAN" 3 996.5604 1.59 44155 9298 2 996.561335 499.2875 Protein PRRC2B OS=Homo sapiens OX=9606 GN=PRRC2B PE=1 SV=2 6.1 2073.5 - 2.77E+06 - - - 0.9432 - 1.502 0.292 - 244.4 1 2 0 0.0009 9 0 0 0 1.43E+08 9.02E+07 - - - 2.3743 0.9904 221125_WJC_METTL3_EV_vs_WT_F04.09302.09302.2 0.000118 20-Nov Y.LLSSAYVDSHK.W "sp|Q92552|RT27_HUMAN,tr|E5RJ73|E5RJ73_HUMAN" 2 1218.6245 0.73 44159 9302 2 1218.625071 610.3195 "28S ribosomal protein S27, mitochondrial OS=Homo sapiens OX=9606 GN=MRPS27 PE=1 SV=3" 6.74 2074 - 495142 - - - 0.5079 - 1.797 0.527 - 294 1 1 0 0.0006 11 0 0 0 9.75E+06 1.33E+07 - - - 4.5188 0.9831 221125_WJC_METTL3_EV_vs_WT_F04.09306.09306.2 0.00121 20-Sep S.SLGGGFGGGSR.G sp|P35527|K1C9_HUMAN 1 950.457 115.82 44161 9306 2 950.456492 476.2358 "Keratin, type I cytoskeletal 9 OS=Homo sapiens OX=9606 GN=KRT9 PE=1 SV=3" 9.47 2074.5 - 9.65E+06 - - - -0.5271 - 1.516 0.474 - 159.8 1 1 0 -0.0005 11 0 0 0 1.67E+09 1.44E+07 - - - 3.6674 0.9994 221125_WJC_METTL3_EV_vs_WT_F04.09311.09311.2 0.00038 20-Jul K.TPQSMQSTLDR[166.11].F "sp|Q9UJA3|MCM8_HUMAN,tr|A0A494C100|A0A494C100_HUMAN" 2 1272.6008 5.27 44166 9311 2 1272.599936 637.3077 DNA helicase MCM8 OS=Homo sapiens OX=9606 GN=MCM8 PE=1 SV=2 5.5 2075.1 - 162988 - - - -0.6554 - 1.397 0.395 - 146.4 1 2 0 -0.0008 11 0 0 0 2.80E+07 5.31E+06 - - - 2.8626 0.9999 221125_WJC_METTL3_EV_vs_WT_F04.09314.09314.2 1.16E-05 20-Sep R.AASAYAVGDVK.C "sp|P13861|KAP2_HUMAN,tr|H7C330|H7C330_HUMAN" 2 1050.5346 42.22 44167 9314 2 1050.535495 526.2746 cAMP-dependent protein kinase type II-alpha regulatory subunit OS=Homo sapiens OX=9606 GN=PRKAR2A PE=1 SV=2 5.88 2075.6 - 2.72E+06 - - - 0.8757 - 2.175 0.511 - 376.1 1 2 0 0.0009 11 0 0 0 9.13E+07 2.16E+06 - - - 4.917 0.9986 221125_WJC_METTL3_EV_vs_WT_F04.09315.09315.2 0.0607 18-Sep R.NVVAC[160.03]ESIGR[166.11].V sp|Q9H0U6|RM18_HUMAN 1 1113.5476 1.37 44168 9315 2 1113.550038 557.7811 "39S ribosomal protein L18, mitochondrial OS=Homo sapiens OX=9606 GN=MRPL18 PE=1 SV=1" 5.99 2075.7 - 571167 - - - 2.1777 - 1.699 0.326 - 276.2 1 2 0 0.0024 10 0 0 0 2.02E+07 1.48E+07 - - - 2.9276 0.9992 221125_WJC_METTL3_EV_vs_WT_F04.09316.09316.2 0.0496 16-Jul K.EQAVQVPVK[136.11].G "sp|Q5JSZ5|PRC2B_HUMAN,tr|A0A804HKC3|A0A804HKC3_HUMAN,tr|A0A804HJR4|A0A804HJR4_HUMAN" 3 1004.5746 1.59 44169 9316 2 1004.573736 503.2946 Protein PRRC2B OS=Homo sapiens OX=9606 GN=PRRC2B PE=1 SV=2 6.1 2075.7 - 3.06E+06 - - - -0.8551 - 1.395 0.361 - 162.6 1 2 0 -0.0009 9 0 0 0 1.43E+08 9.02E+07 - - - 2.6702 0.9978 221125_WJC_METTL3_EV_vs_WT_F04.09321.09321.2 0.0264 16-Jun K.DVDGAYMTK.V sp|P04264|K2C1_HUMAN 1 998.4379 241.3 44172 9321 2 998.436731 500.2262 "Keratin, type II cytoskeletal 1 OS=Homo sapiens OX=9606 GN=KRT1 PE=1 SV=6" 4.21 2076.4 - 5.48E+06 - - - -1.1678 - 1.323 0.281 - 69.6 1 2 0 -0.0012 9 0 0 0 4.44E+08 1.84E+06 - - - 1.9259 0.9979 221125_WJC_METTL3_EV_vs_WT_F04.09322.09322.3 8.19E-07 15/40 Y.LLSSAYVDSHK.W "sp|Q92552|RT27_HUMAN,tr|E5RJ73|E5RJ73_HUMAN" 2 1218.6245 8.29 44173 9322 3 1218.623062 407.2154 "28S ribosomal protein S27, mitochondrial OS=Homo sapiens OX=9606 GN=MRPS27 PE=1 SV=3" 6.74 2076.4 - 3.05E+06 - - - -1.1406 - 2.499 0.539 - 227 1 1 0 -0.0014 11 0 0 0 6.27E+08 7.57E+07 - - - 7.1508 0.9289 221125_WJC_METTL3_EV_vs_WT_F04.09327.09327.2 0.0253 20-Sep R.AAPGAEFAPNK[136.11].R "sp|Q15233|NONO_HUMAN,tr|A0A7I2V535|A0A7I2V535_HUMAN,tr|A0A7I2V4K9|A0A7I2V4K9_HUMAN,tr|A0A7I2V4J2|A0A7I2V4J2_HUMAN,tr|A0A7I2V5Y7|A0A7I2V5Y7_HUMAN" 5 1079.5491 0.63 44174 9327 2 1080.552915 540.7818 Non-POU domain-containing octamer-binding protein OS=Homo sapiens OX=9606 GN=NONO PE=1 SV=4 6.05 2077.2 - 1.63E+06 - - - 929.8382 - 1.727 0.23 - 234.2 1 2 0 1.0038 11 0 0 0 7.46E+07 1.19E+08 - - - 1.9027 0.9995 221125_WJC_METTL3_EV_vs_WT_F04.09328.09328.2 0.000393 20-Sep R.LSPENNQVLTK[136.11].K "sp|Q16514|TAF12_HUMAN,tr|A0A804HLG9|A0A804HLG9_HUMAN" 2 1249.6758 1.7 44175 9328 2 1249.672609 625.8452 Transcription initiation factor TFIID subunit 12 OS=Homo sapiens OX=9606 GN=TAF12 PE=1 SV=1 6 2077.3 - 539485 - - - -2.5263 - 1.982 0.491 - 290.8 1 2 0 -0.0032 11 0 0 0 1.30E+08 7.64E+07 - - - 4.5172 0.9949 221125_WJC_METTL3_EV_vs_WT_F04.09332.09332.2 0.02 16-Sep K.LSDIGVEDK[136.11].S sp|Q96F45|ZN503_HUMAN 1 982.5062 4.81 44177 9332 2 982.502098 492.2604 Zinc finger protein 503 OS=Homo sapiens OX=9606 GN=ZNF503 PE=1 SV=1 4.03 2077.8 - 840121 - - - -4.2168 - 1.97 0.282 - 183.3 1 2 0 -0.0041 9 0 0 0 1.19E+08 2.47E+07 - - - 3.0841 0.9921 221125_WJC_METTL3_EV_vs_WT_F04.09334.09334.2 0.0481 18-Jul R.NVVAC[160.03]ESIGR.V sp|Q9H0U6|RM18_HUMAN 1 1103.5393 1.35 44179 9334 2 1103.536414 552.7769 "39S ribosomal protein L18, mitochondrial OS=Homo sapiens OX=9606 GN=MRPL18 PE=1 SV=1" 5.99 2078.1 - 1.08E+06 - - - -2.6542 - 1.128 0.312 - 147.5 1 2 0 -0.0029 10 0 0 0 2.02E+07 1.50E+07 - - - 1.6807 0.9995 221125_WJC_METTL3_EV_vs_WT_F04.09335.09335.2 0.0295 20-Oct R.AGELTEDEVER[166.11].V sp|P62269|RS18_HUMAN 1 1256.576 1.06 44180 9335 2 1256.572497 629.2953 40S ribosomal protein S18 OS=Homo sapiens OX=9606 GN=RPS18 PE=1 SV=3 3.91 2078.2 - 527982 - - - -2.7838 - 2.401 0.46 - 505.9 1 2 0 -0.0035 11 0 0 0 1.60E+09 1.51E+09 - - - 4.8069 0.9997 221125_WJC_METTL3_EV_vs_WT_F04.09336.09336.2 2.49E-05 20-Nov R.AGELTEDEVER.V sp|P62269|RS18_HUMAN 1 1246.5677 1.06 44181 9336 2 1246.564421 624.2911 40S ribosomal protein S18 OS=Homo sapiens OX=9606 GN=RPS18 PE=1 SV=3 3.91 2078.3 - 410468 - - - -2.6505 - 2.464 0.526 - 607.5 1 2 0 -0.0033 11 0 0 0 1.60E+09 1.51E+09 - - - 5.3645 0.9956 221125_WJC_METTL3_EV_vs_WT_F04.09341.09341.2 0.192 12-Jul R.QQEYDFK.M sp|Q03252|LMNB2_HUMAN 1 956.424 2.6 44184 9341 2 956.42349 479.2193 Lamin-B2 OS=Homo sapiens OX=9606 GN=LMNB2 PE=1 SV=4 4.37 2078.9 - 1.82E+06 - - - -0.4935 - 1.259 0.195 - 243 1 2 0 -0.0005 7 0 0 0 5.88E+07 2.26E+07 - - - 1.2109 0.9998 221125_WJC_METTL3_EV_vs_WT_F04.09342.09342.2 0.00745 20-Oct R.ELEQANDDLER.A "sp|Q9GZM8|NDEL1_HUMAN,sp|Q9NXR1|NDE1_HUMAN,tr|I3L522|I3L522_HUMAN,tr|I3L2S8|I3L2S8_HUMAN,tr|A0A6Q8PEY3|A0A6Q8PEY3_HUMAN,tr|I3L3G9|I3L3G9_HUMAN,tr|A0A6Q8PHH1|A0A6Q8PHH1_HUMAN,tr|A0A6Q8PGV6|A0A6Q8PGV6_HUMAN,tr|J3QL85|J3QL85_HUMAN,tr|A0A0J9YYF5|A0A0J9YYF5_HUMAN,tr|J3KRK9|J3KRK9_HUMAN,tr|A6NIZ0|A6NIZ0_HUMAN,tr|A0A6Q8PG46|A0A6Q8PG46_HUMAN" 13 1330.6001 5.33 44185 9342 2 1330.598747 666.3073 Nuclear distribution protein nudE-like 1 OS=Homo sapiens OX=9606 GN=NDEL1 PE=1 SV=1 3.83 2079.1 - 353012 - - - -1.0078 - 2.224 0.456 - 478.6 1 2 0 -0.0013 11 0 0 0 8.66E+06 1.62E+06 - - - 4.5709 0.9988 221125_WJC_METTL3_EV_vs_WT_F04.09351.09351.2 0.014 18-Sep R.ESAINVAEGK.K "sp|Q9UJZ1|STML2_HUMAN,tr|A0A087WYB4|A0A087WYB4_HUMAN,tr|F2Z2I8|F2Z2I8_HUMAN" 3 1016.5138 1.3 44189 9351 2 1016.511172 509.2642 "Stomatin-like protein 2, mitochondrial OS=Homo sapiens OX=9606 GN=STOML2 PE=1 SV=1" 4.53 2080.1 - 4.64E+06 - - - -2.6237 - 1.824 0.361 - 263.8 1 2 0 -0.0027 10 0 0 0 1.35E+08 1.04E+08 - - - 3.3842 0.9979 221125_WJC_METTL3_EV_vs_WT_F04.09352.09352.2 0.183 16-Aug K.YIDQEELNK.T "sp|Q58FF8|H90B2_HUMAN,sp|P08238|HS90B_HUMAN,sp|P07900|HS90A_HUMAN,sp|Q14568|HS902_HUMAN" 4 1150.5506 0.74 44190 9352 2 1150.54791 576.2826 Putative heat shock protein HSP 90-beta 2 OS=Homo sapiens OX=9606 GN=HSP90AB2P PE=1 SV=2 4.14 2080.1 - 4.30E+06 - - - -2.3545 - 1.331 0.374 - 139.3 1 2 0 -0.0027 9 0 0 0 4.95E+08 6.73E+08 - - - 2.6297 0.9991 221125_WJC_METTL3_EV_vs_WT_F04.09358.09358.3 0.00546 Dec-40 K.FAEHGETLAMK[136.11].G "sp|Q9BXJ9|NAA15_HUMAN,sp|Q6N069|NAA16_HUMAN,tr|A0A0B4J1W3|A0A0B4J1W3_HUMAN" 3 1240.6002 0.17 44194 9358 3 1240.597503 414.5407 "N-alpha-acetyltransferase 15, NatA auxiliary subunit OS=Homo sapiens OX=9606 GN=NAA15 PE=1 SV=1" 5.4 2080.9 - 598307 - - - -2.1401 - 1.634 0.359 - 102.4 1 2 0 -0.0027 11 0 0 0 4.05E+06 2.36E+07 - - - 3.9367 0.9999 221125_WJC_METTL3_EV_vs_WT_F04.09359.09359.3 3.44E-05 13/36 K.LTPEQLHSMR.Q "sp|Q9Y2R0|COA3_HUMAN,tr|K7EPV0|K7EPV0_HUMAN" 2 1210.6128 1.09 44195 9359 3 1210.610554 404.5449 "Cytochrome c oxidase assembly factor 3 homolog, mitochondrial OS=Homo sapiens OX=9606 GN=COA3 PE=1 SV=1" 6.75 2081.1 - 547232 - - - -1.89 - 2.238 0.424 - 271.3 1 2 0 -0.0023 10 0 0 0 1.86E+08 1.71E+08 - - - 5.6192 0.9968 221125_WJC_METTL3_EV_vs_WT_F04.09365.09365.2 0.0106 16-Sep K.ALYEHLTAK[136.11].N "sp|P42704|LPPRC_HUMAN,tr|A0A804HI14|A0A804HI14_HUMAN,tr|A0A804HL40|A0A804HL40_HUMAN,tr|A0A804HKJ0|A0A804HKJ0_HUMAN,tr|A0A804HKR3|A0A804HKR3_HUMAN,tr|A0A804HIN4|A0A804HIN4_HUMAN,tr|A0A804HLG8|A0A804HLG8_HUMAN,tr|A0A804HHY9|A0A804HHY9_HUMAN,tr|A0A804HJZ1|A0A804HJZ1_HUMAN,tr|A0A804HK30|A0A804HK30_HUMAN,tr|A0A804HKI2|A0A804HKI2_HUMAN,tr|A0A804HIG4|A0A804HIG4_HUMAN" 12 1052.5746 2.43 44199 9365 2 1052.57725 527.2946 "Leucine-rich PPR motif-containing protein, mitochondrial OS=Homo sapiens OX=9606 GN=LRPPRC PE=1 SV=3" 6.79 2081.8 - 1.57E+06 - - - 2.5224 - 1.795 0.223 - 262.5 1 2 0 0.0027 9 0 0 0 9.77E+07 4.02E+07 - - - 2.3797 0.9995 221125_WJC_METTL3_EV_vs_WT_F04.09366.09366.3 0.000265 13/48 R.LHPELSGPGVAAK[136.11].V sp|Q6DD87|ZN787_HUMAN 1 1282.7125 0.91 44200 9366 3 1282.707633 428.5781 Zinc finger protein 787 OS=Homo sapiens OX=9606 GN=ZNF787 PE=1 SV=4 6.75 2081.9 - 777664 - - - -3.7834 - 2.558 0.403 - 281.1 1 2 0 -0.0049 13 0 0 0 1.30E+07 1.42E+07 - - - 5.5782 0.9989 221125_WJC_METTL3_EV_vs_WT_F04.09370.09370.2 0.0767 14-Dec K.KGDLLLNR.V sp|Q15008|PSMD6_HUMAN 1 927.5502 0.56 44202 9370 2 927.548326 464.7824 26S proteasome non-ATPase regulatory subunit 6 OS=Homo sapiens OX=9606 GN=PSMD6 PE=1 SV=1 8.75 2082.5 - 842174 - - - -1.9826 - 1.698 0.322 - 520.3 1 2 0 -0.0018 8 0 0 0 2.33E+07 4.17E+07 - - - 3.0155 0.9999 221125_WJC_METTL3_EV_vs_WT_F04.09372.09372.3 1.57E-05 16/48 R.LHPELSGPGVAAK.V sp|Q6DD87|ZN787_HUMAN 1 1274.6983 0.91 44204 9372 3 1274.697686 425.9067 Zinc finger protein 787 OS=Homo sapiens OX=9606 GN=ZNF787 PE=1 SV=4 6.75 2082.7 - 657689 - - - -0.4707 - 2.551 0.427 - 338 1 2 0 -0.0006 13 0 0 0 1.30E+07 1.44E+07 - - - 5.8395 0.9784 221125_WJC_METTL3_EV_vs_WT_F04.09373.09373.2 0.0834 18-Aug R.STTPTSSPFR.A "sp|Q9Y520|PRC2C_HUMAN,tr|E7EPN9|E7EPN9_HUMAN,tr|A0A2R8Y424|A0A2R8Y424_HUMAN,tr|H7C5N8|H7C5N8_HUMAN,tr|A0A2R8Y7F4|A0A2R8Y7F4_HUMAN,tr|A0A2R8YET2|A0A2R8YET2_HUMAN" 6 1079.5247 4.13 44205 9373 2 1079.518722 540.7696 Protein PRRC2C OS=Homo sapiens OX=9606 GN=PRRC2C PE=1 SV=4 9.47 2082.8 - 543967 - - - -5.5728 - 1.776 0.267 - 190.4 1 2 0 -0.006 10 0 0 0 3.27E+07 7.91E+06 - - - 2.6144 0.9994 221125_WJC_METTL3_EV_vs_WT_F04.09374.09374.2 0.0013 18-Aug K.YLEQQEGQLK.H sp|P07476|INVO_HUMAN 1 1234.6194 999 44206 9374 2 1234.620818 618.317 Involucrin OS=Homo sapiens OX=9606 GN=IVL PE=1 SV=2 4.53 2083 - 335453 - - - 1.1753 - 1.444 0.423 - 156.4 1 2 0 0.0015 10 0 0 0 5.36E+06 0.00E+00 - - - 3.1904 0.9974 221125_WJC_METTL3_EV_vs_WT_F04.09377.09377.2 0.0159 14-Jul K.SVMEELK[136.11]R[166.11].L "sp|Q96A72|MGN2_HUMAN,sp|P61326|MGN_HUMAN,tr|F5H6N1|F5H6N1_HUMAN,tr|F5H3U9|F5H3U9_HUMAN,tr|F5H6P7|F5H6P7_HUMAN" 5 1008.5393 1.43 44207 9377 2 1008.537008 505.2769 Protein mago nashi homolog 2 OS=Homo sapiens OX=9606 GN=MAGOHB PE=1 SV=1 5.86 2083.3 - 1.43E+06 - - - -2.2587 - 1.427 0.305 - 161.1 1 2 0 -0.0023 8 0 0 0 6.64E+07 4.66E+07 - - - 2.3654 0.9967 221125_WJC_METTL3_EV_vs_WT_F04.09378.09378.3 0.0023 Aug-32 R.MDYEDDR[166.11]LR[166.11].D "sp|P43243|MATR3_HUMAN,tr|A8MXP9|A8MXP9_HUMAN,tr|D6R991|D6R991_HUMAN,tr|A0A0R4J2E8|A0A0R4J2E8_HUMAN,tr|D6REM6|D6REM6_HUMAN" 5 1231.5406 1.25 44208 9378 3 1231.536449 411.5208 Matrin-3 OS=Homo sapiens OX=9606 GN=MATR3 PE=1 SV=2 4.23 2083.4 - 2.65E+06 - - - -3.3917 - 1.4 0.475 - 132.9 1 2 1 -0.0042 9 0 0 0 1.25E+09 9.98E+08 - - - 4.8487 0.9957 221125_WJC_METTL3_EV_vs_WT_F04.09379.09379.2 0.0872 14-Jul K.TVVFQQER.D "sp|Q15643|TRIPB_HUMAN,tr|H0YJ97|H0YJ97_HUMAN" 2 1005.5243 1.14 44209 9379 2 1005.522783 503.7694 Thyroid receptor-interacting protein 11 OS=Homo sapiens OX=9606 GN=TRIP11 PE=1 SV=3 5.66 2083.5 - 2.78E+06 - - - -1.5524 - 1.336 0.222 - 185.3 1 2 0 -0.0016 8 0 0 0 9.01E+07 7.91E+07 - - - 1.5539 0.9957 221125_WJC_METTL3_EV_vs_WT_F04.09383.09383.3 0.000778 Oct-32 R.MDYEDDRLR.D "sp|P43243|MATR3_HUMAN,tr|A8MXP9|A8MXP9_HUMAN,tr|D6R991|D6R991_HUMAN,tr|A0A0R4J2E8|A0A0R4J2E8_HUMAN,tr|D6REM6|D6REM6_HUMAN" 5 1211.5241 1.25 44211 9383 3 1211.520692 404.8486 Matrin-3 OS=Homo sapiens OX=9606 GN=MATR3 PE=1 SV=2 4.23 2084 - 2.68E+06 - - - -2.8014 - 1.727 0.364 - 256.7 1 2 1 -0.0034 9 0 0 0 1.25E+09 9.99E+08 - - - 4.244 0.9997 221125_WJC_METTL3_EV_vs_WT_F04.09386.09386.2 0.00016 18-Sep K.MAPTVLVHSR.A "sp|Q6W2J9|BCOR_HUMAN,tr|H7BZ37|H7BZ37_HUMAN,tr|H7C2V9|H7C2V9_HUMAN,tr|H7BYY2|H7BYY2_HUMAN,tr|H7C231|H7C231_HUMAN" 5 1109.6015 1.4 44214 9386 2 1109.600467 555.8081 BCL-6 corepressor OS=Homo sapiens OX=9606 GN=BCOR PE=1 SV=1 9.52 2084.4 - 446987 - - - -0.9751 - 1.925 0.4 - 396.5 1 2 0 -0.0011 10 0 0 0 7.24E+06 5.17E+06 - - - 3.8232 0.9983 221125_WJC_METTL3_EV_vs_WT_F04.09389.09389.2 0.0172 14-Jul K.SVMEELKR.L "sp|Q96A72|MGN2_HUMAN,sp|P61326|MGN_HUMAN,tr|F5H6N1|F5H6N1_HUMAN,tr|F5H3U9|F5H3U9_HUMAN,tr|F5H6P7|F5H6P7_HUMAN" 5 990.5168 1.42 44216 9389 2 990.515314 496.2657 Protein mago nashi homolog 2 OS=Homo sapiens OX=9606 GN=MAGOHB PE=1 SV=1 5.86 2084.7 - 2.09E+06 - - - -1.5164 - 1.378 0.309 - 165.3 1 2 0 -0.0015 8 0 0 0 6.74E+07 4.76E+07 - - - 2.2898 0.9995 221125_WJC_METTL3_EV_vs_WT_F04.09391.09391.2 0.00107 18-Aug R.GNVLVLSQHK[136.11].F "sp|Q14671|PUM1_HUMAN,tr|Q5T1Z8|Q5T1Z8_HUMAN,tr|H0YDK8|H0YDK8_HUMAN,tr|H0YC97|H0YC97_HUMAN,tr|H0YEH2|H0YEH2_HUMAN,tr|Q5T1Z4|Q5T1Z4_HUMAN,tr|H0YDC5|H0YDC5_HUMAN,tr|E9PR38|E9PR38_HUMAN" 8 1101.6386 2.1 44217 9391 2 1101.63741 551.8266 Pumilio homolog 1 OS=Homo sapiens OX=9606 GN=PUM1 PE=1 SV=3 8.76 2084.9 - 871681 - - - -1.0739 - 1.497 0.418 - 259.5 1 2 0 -0.0012 10 0 0 0 3.59E+07 1.71E+07 - - - 3.2542 0.9996 221125_WJC_METTL3_EV_vs_WT_F04.09393.09393.2 0.000415 24-Nov K.GASQAGMLAPGTR[166.11].R "sp|Q15417|CNN3_HUMAN,tr|E9PDU6|E9PDU6_HUMAN" 2 1225.6113 0.22 44219 9393 2 1225.611493 613.8129 Calponin-3 OS=Homo sapiens OX=9606 GN=CNN3 PE=1 SV=1 9.75 2085.2 - 846929 - - - 0.1779 - 1.915 0.333 - 435.7 1 2 0 0.0002 13 0 0 0 4.41E+06 1.98E+07 - - - 3.168 0.9991 221125_WJC_METTL3_EV_vs_WT_F04.09398.09398.2 0.0831 14-Sep R.QQLLEEER.T sp|Q9NSI2|SLX9_HUMAN 1 1043.5247 1.68 44222 9398 2 1043.523358 522.7696 Ribosome biogenesis protein SLX9 homolog OS=Homo sapiens OX=9606 GN=SLX9 PE=1 SV=2 4.25 2085.8 - 5.78E+06 - - - -1.3224 - 1.711 0.282 - 394.5 1 2 0 -0.0014 8 0 0 0 6.38E+08 3.80E+08 - - - 2.7432 0.9964 221125_WJC_METTL3_EV_vs_WT_F04.09399.09399.2 0.00773 12-Jul K.WDVSTTK[136.11].A "sp|P07814|SYEP_HUMAN,tr|V9GZ76|V9GZ76_HUMAN,tr|V9GYZ6|V9GYZ6_HUMAN" 3 843.4218 2.22 44223 9399 2 843.419525 422.7182 Bifunctional glutamate\proline--tRNA ligase OS=Homo sapiens OX=9606 GN=EPRS1 PE=1 SV=5 5.84 2085.8 - 2.46E+06 - - - -2.6772 - 1.406 0.301 - 200.7 1 2 0 -0.0023 7 0 0 0 1.10E+08 4.94E+07 - - - 2.3432 0.9992 221125_WJC_METTL3_EV_vs_WT_F04.09400.09400.2 0.00247 14-Sep K.INEEISVK.H "sp|Q9BUJ2|HNRL1_HUMAN,tr|M0QYZ0|M0QYZ0_HUMAN,tr|A0A0A0MRA5|A0A0A0MRA5_HUMAN,tr|M0R3F1|M0R3F1_HUMAN,tr|B7Z4B8|B7Z4B8_HUMAN,tr|M0QYI8|M0QYI8_HUMAN,tr|M0QYM5|M0QYM5_HUMAN" 7 930.5022 1.64 44224 9400 2 930.50107 466.2584 Heterogeneous nuclear ribonucleoprotein U-like protein 1 OS=Homo sapiens OX=9606 GN=HNRNPUL1 PE=1 SV=2 4.53 2085.9 - 1.35E+06 - - - -1.2273 - 1.444 0.358 - 189.1 1 2 0 -0.0011 8 0 0 0 3.24E+07 1.98E+07 - - - 2.7929 0.9991 221125_WJC_METTL3_EV_vs_WT_F04.09408.09408.2 0.0123 16-Jun K.EFTEAVEAK.Q "sp|P35232|PHB_HUMAN,tr|C9JZ20|C9JZ20_HUMAN,tr|E7ESE2|E7ESE2_HUMAN,tr|E9PCW0|E9PCW0_HUMAN,tr|C9JW96|C9JW96_HUMAN" 5 1022.492 0.02 44230 9408 2 1022.491865 512.2533 Prohibitin OS=Homo sapiens OX=9606 GN=PHB PE=1 SV=1 4.25 2086.8 - 461462 - - - -0.1721 - 1.448 0.318 - 124.6 1 2 0 -0.0002 9 0 0 0 2.58E+07 1.50E+09 - - - 2.4607 0.9918 221125_WJC_METTL3_EV_vs_WT_F04.09409.09409.2 0.328 18-Aug R.YPDGIISKPK.N sp|Q86U44|MTA70_HUMAN 1 1116.6179 0 44231 9409 2 1116.61832 559.3162 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 8.5 2086.9 - 420665 - - - 0.3672 - 1.19 0.171 - 149.8 1 2 0 0.0004 10 0 0 0 1.36E+07 1.56E+10 - - - 0.7894 0.9978 221125_WJC_METTL3_EV_vs_WT_F04.09414.09414.2 6.09 14-Aug K.INEEISVK[136.11].H "sp|Q9BUJ2|HNRL1_HUMAN,tr|M0QYZ0|M0QYZ0_HUMAN,tr|A0A0A0MRA5|A0A0A0MRA5_HUMAN,tr|M0R3F1|M0R3F1_HUMAN,tr|B7Z4B8|B7Z4B8_HUMAN,tr|M0QYI8|M0QYI8_HUMAN,tr|M0QYM5|M0QYM5_HUMAN" 7 938.5164 1.68 44234 9414 2 938.514995 470.2655 Heterogeneous nuclear ribonucleoprotein U-like protein 1 OS=Homo sapiens OX=9606 GN=HNRNPUL1 PE=1 SV=2 4.53 2087.5 - 1.30E+06 - - - -1.5098 - 1.776 0.178 - 158 1 2 0 -0.0014 8 0 0 0 3.18E+07 1.89E+07 - - - 2.0875 0.9978 221125_WJC_METTL3_EV_vs_WT_F04.09417.09417.2 0.027 16-Nov R.SGAVEETFR[166.11].L sp|Q6YN16|HSDL2_HUMAN 1 1004.4802 0.55 44235 9417 2 1004.476187 503.2474 Hydroxysteroid dehydrogenase-like protein 2 OS=Homo sapiens OX=9606 GN=HSDL2 PE=1 SV=1 4.53 2087.9 - 3.04E+06 - - - -4.0389 - 2.151 0.356 - 549.2 1 2 0 -0.0041 9 0 0 0 5.26E+07 9.53E+07 - - - 3.885 0.9236 221125_WJC_METTL3_EV_vs_WT_F04.09422.09422.2 1.92 12-May K.NPSVNWK[136.11].H sp|P55060|XPO2_HUMAN 1 851.4381 1.84 44238 9422 2 851.437931 426.7263 Exportin-2 OS=Homo sapiens OX=9606 GN=CSE1L PE=1 SV=3 8.75 2088.4 - 741869 - - - -0.2008 - 1.072 0.045 - 82.1 5 2 0 -0.0002 7 0 0 0 4.53E+07 2.47E+07 - - - -0.7186 1 221125_WJC_METTL3_EV_vs_WT_F04.09423.09423.2 1.11E-12 14/26 A.AAAAAAAYSDGYGR[166.11].V "sp|O43251|RFOX2_HUMAN,tr|B0QYV1|B0QYV1_HUMAN,tr|A0A0G2JRD1|A0A0G2JRD1_HUMAN,tr|A0A0G2JRA5|A0A0G2JRA5_HUMAN,tr|S4R3K7|S4R3K7_HUMAN" 5 1323.6083 1.38 44239 9423 2 1323.603927 662.8114 RNA binding protein fox-1 homolog 2 OS=Homo sapiens OX=9606 GN=RBFOX2 PE=1 SV=3 5.88 2088.5 - 189196 - - - -3.3031 - 2.856 0.642 - 762.6 1 1 0 -0.0044 14 0 0 0 1.53E+07 1.11E+07 - - - 6.4149 0.9536 221125_WJC_METTL3_EV_vs_WT_F04.09424.09424.2 0.0142 14-Aug T.PEQLHSMR.Q "sp|Q9Y2R0|COA3_HUMAN,tr|K7EPV0|K7EPV0_HUMAN" 2 996.4811 0.59 44240 9424 2 996.479209 499.2478 "Cytochrome c oxidase assembly factor 3 homolog, mitochondrial OS=Homo sapiens OX=9606 GN=COA3 PE=1 SV=1" 7.18 2088.6 - 1.00E+06 - - - -1.8967 - 1.894 0.309 - 283.7 1 1 0 -0.0019 8 0 0 0 3.19E+07 5.44E+07 - - - 3.2489 1 221125_WJC_METTL3_EV_vs_WT_F04.09426.09426.2 4.10E-06 13/18 R.TYQASSAAFR[166.11].Y sp|Q92567|F168A_HUMAN 1 1110.5333 1.26 44241 9426 2 1110.532389 556.2739 Protein FAM168A OS=Homo sapiens OX=9606 GN=FAM168A PE=1 SV=2 8.41 2088.8 - 1.82E+06 - - - -0.859 - 2.398 0.582 - 538 1 2 0 -0.001 10 0 0 0 6.64E+07 5.25E+07 - - - 5.7807 0.9998 221125_WJC_METTL3_EV_vs_WT_F04.09429.09429.2 1.86E-07 18-Dec R.DGSNVIVTER.V sp|Q02413|DSG1_HUMAN 1 1088.5462 156.05 44243 9429 2 1088.544511 545.2804 Desmoglein-1 OS=Homo sapiens OX=9606 GN=DSG1 PE=1 SV=2 4.37 2089.1 - 5.50E+06 - - - -1.5534 - 2.218 0.556 - 635.3 1 2 0 -0.0017 10 0 0 0 1.22E+08 7.82E+05 - - - 5.3707 0.9981 221125_WJC_METTL3_EV_vs_WT_F04.09430.09430.2 0.0201 18-Aug R.GNVLVLSQHK.F "sp|Q14671|PUM1_HUMAN,tr|Q5T1Z8|Q5T1Z8_HUMAN,tr|H0YDK8|H0YDK8_HUMAN,tr|H0YC97|H0YC97_HUMAN,tr|H0YEH2|H0YEH2_HUMAN,tr|Q5T1Z4|Q5T1Z4_HUMAN,tr|H0YDC5|H0YDC5_HUMAN,tr|E9PR38|E9PR38_HUMAN" 8 1093.6244 2.1 44244 9430 2 1093.623283 547.8195 Pumilio homolog 1 OS=Homo sapiens OX=9606 GN=PUM1 PE=1 SV=3 8.76 2089.2 - 1.53E+06 - - - -1.015 - 1.321 0.292 - 180.7 1 2 0 -0.0011 10 0 0 0 3.59E+07 1.71E+07 - - - 1.9744 0.9998 221125_WJC_METTL3_EV_vs_WT_F04.09437.09437.2 9.21E-07 22-Nov K.MDSTANEVEAVK.V "sp|P07237|PDIA1_HUMAN,tr|A0A7P0TA97|A0A7P0TA97_HUMAN,tr|A0A7P0T8C0|A0A7P0T8C0_HUMAN,tr|H7BZ94|H7BZ94_HUMAN,tr|B3KTQ9|B3KTQ9_HUMAN,tr|A0A7P0TA71|A0A7P0TA71_HUMAN,tr|I3L4M2|I3L4M2_HUMAN,tr|A0A7P0T9K9|A0A7P0T9K9_HUMAN,tr|H0Y3Z3|H0Y3Z3_HUMAN,tr|A0A7P0TA35|A0A7P0TA35_HUMAN,tr|A0A7P0TB26|A0A7P0TB26_HUMAN,tr|I3L0S0|I3L0S0_HUMAN,tr|I3L3P5|I3L3P5_HUMAN,tr|A0A7P0T8J3|A0A7P0T8J3_HUMAN,tr|A0A7P0T8X1|A0A7P0T8X1_HUMAN" 15 1292.5918 1.44 44249 9437 2 1292.588861 647.3032 Protein disulfide-isomerase OS=Homo sapiens OX=9606 GN=P4HB PE=1 SV=3 4.14 2090.1 - 628204 - - - -2.2985 - 2.367 0.588 - 461.9 1 2 0 -0.003 12 0 0 0 7.31E+07 5.09E+07 - - - 5.6501 1 221125_WJC_METTL3_EV_vs_WT_F04.09438.09438.2 3.90E-09 22-Dec K.MDSTANEVEAVK[136.11].V "sp|P07237|PDIA1_HUMAN,tr|A0A7P0TA97|A0A7P0TA97_HUMAN,tr|A0A7P0T8C0|A0A7P0T8C0_HUMAN,tr|H7BZ94|H7BZ94_HUMAN,tr|B3KTQ9|B3KTQ9_HUMAN,tr|A0A7P0TA71|A0A7P0TA71_HUMAN,tr|I3L4M2|I3L4M2_HUMAN,tr|A0A7P0T9K9|A0A7P0T9K9_HUMAN,tr|H0Y3Z3|H0Y3Z3_HUMAN,tr|A0A7P0TA35|A0A7P0TA35_HUMAN,tr|A0A7P0TB26|A0A7P0TB26_HUMAN,tr|I3L0S0|I3L0S0_HUMAN,tr|I3L3P5|I3L3P5_HUMAN,tr|A0A7P0T8J3|A0A7P0T8J3_HUMAN,tr|A0A7P0T8X1|A0A7P0T8X1_HUMAN" 15 1300.606 1.44 44250 9438 2 1300.60655 651.3103 Protein disulfide-isomerase OS=Homo sapiens OX=9606 GN=P4HB PE=1 SV=3 4.14 2090.2 - 613977 - - - 0.3983 - 2.611 0.587 - 553.5 1 2 0 0.0005 12 0 0 0 7.31E+07 5.09E+07 - - - 5.9016 0.9989 221125_WJC_METTL3_EV_vs_WT_F04.09440.09440.2 0.00195 20-Aug R.C[160.03]GQGASLTVVK.Q "sp|Q96C92|ENTR1_HUMAN,tr|H7C331|H7C331_HUMAN" 2 1118.5754 1.74 44252 9440 2 1118.573426 560.295 Endosome-associated-trafficking regulator 1 OS=Homo sapiens OX=9606 GN=ENTR1 PE=1 SV=3 8.22 2090.5 - 375123 - - - -1.7594 - 1.607 0.337 - 195.3 1 2 0 -0.002 11 0 0 0 6.05E+06 3.48E+06 - - - 2.8127 0.9998 221125_WJC_METTL3_EV_vs_WT_F04.09447.09447.2 5.32E-05 20-Oct R.EIGQSVDEVEK[136.11].L "sp|Q01082|SPTB2_HUMAN,tr|A0A087WUZ3|A0A087WUZ3_HUMAN" 2 1239.6074 1.24 44257 9447 2 1239.606034 620.811 "Spectrin beta chain, non-erythrocytic 1 OS=Homo sapiens OX=9606 GN=SPTBN1 PE=1 SV=2" 4 2091.2 - 846598 - - - -1.1116 - 1.903 0.45 - 278.6 1 2 0 -0.0014 11 0 0 0 3.74E+07 3.02E+07 - - - 4.1049 0.9999 221125_WJC_METTL3_EV_vs_WT_F04.09448.09448.2 0.00129 14-Dec K.HVEDLLTK.L sp|P12270|TPR_HUMAN 1 953.5182 3.33 44258 9448 2 953.517842 477.7664 Nucleoprotein TPR OS=Homo sapiens OX=9606 GN=TPR PE=1 SV=3 5.32 2091.3 - 831506 - - - -0.3713 - 2.183 0.483 - 623.7 1 2 0 -0.0004 8 0 0 0 1.22E+08 3.65E+07 - - - 4.9629 0.8643 221125_WJC_METTL3_EV_vs_WT_F04.09459.09459.2 0.384 22-Jun R.YFEEESK[136.11]DLAGR[166.11].L "sp|A8MQT2|GOG8B_HUMAN,sp|A7E2F4|GOG8A_HUMAN,tr|C9J1B5|C9J1B5_HUMAN" 3 1460.6902 0.001 44266 9459 2 1460.692666 731.3524 Golgin subfamily A member 8B OS=Homo sapiens OX=9606 GN=GOLGA8B PE=2 SV=2 4.41 2092.7 - 275493 - - - 1.6581 - 1.163 0.188 - 108.7 1 2 1 0.0024 12 0 0 0 0.00E+00 4.71E+06 - - - 0.8261 0.9995 221125_WJC_METTL3_EV_vs_WT_F04.09460.09460.2 0.0051 18-Sep K.LAQAYYESTR.K sp|P20930|FILA_HUMAN 1 1200.5775 150.29 44267 9460 2 1200.574922 601.296 Filaggrin OS=Homo sapiens OX=9606 GN=FLG PE=1 SV=3 6 2092.9 - 187892 - - - -2.149 - 2.106 0.388 - 327.4 1 2 0 -0.0026 10 0 0 0 1.18E+07 7.83E+04 - - - 3.9849 0.9998 221125_WJC_METTL3_EV_vs_WT_F04.09465.09465.2 0.000815 14-Nov K.HVEDLLTK[136.11].L sp|P12270|TPR_HUMAN 1 961.5324 3.36 44270 9465 2 961.532511 481.7735 Nucleoprotein TPR OS=Homo sapiens OX=9606 GN=TPR PE=1 SV=3 5.32 2093.4 - 1.51E+06 - - - 0.1196 - 2.2 0.391 - 529.2 1 2 0 0.0001 8 0 0 0 1.23E+08 3.65E+07 - - - 4.3068 0.9998 221125_WJC_METTL3_EV_vs_WT_F04.09468.09468.2 0.00171 16-Sep R.TLLEGEESR.M sp|P04264|K2C1_HUMAN 1 1032.5088 7.39 44272 9468 2 1032.508389 517.2617 "Keratin, type II cytoskeletal 1 OS=Homo sapiens OX=9606 GN=KRT1 PE=1 SV=6" 4.25 2093.8 - 5.70E+07 - - - -0.3535 - 1.747 0.503 - 244.2 1 2 0 -0.0004 9 0 0 0 1.96E+09 2.65E+08 - - - 4.3701 0.9998 221125_WJC_METTL3_EV_vs_WT_F04.09470.09470.2 0.00029 18-Nov K.QADVNLVNAK.L "sp|O43175|SERA_HUMAN,tr|A0A2C9F2M7|A0A2C9F2M7_HUMAN,tr|A0A286YF22|A0A286YF22_HUMAN" 3 1070.572 1.23 44273 9470 2 1070.573084 536.2933 D-3-phosphoglycerate dehydrogenase OS=Homo sapiens OX=9606 GN=PHGDH PE=1 SV=4 5.84 2094 - 5.52E+06 - - - 0.9911 - 2.193 0.417 - 611.1 1 2 0 0.0011 10 0 0 0 2.42E+08 1.97E+08 - - - 4.3126 0.9998 221125_WJC_METTL3_EV_vs_WT_F04.09471.09471.2 3.67E-06 18-Nov K.QADVNLVNAK[136.11].L "sp|O43175|SERA_HUMAN,tr|A0A2C9F2M7|A0A2C9F2M7_HUMAN,tr|A0A286YF22|A0A286YF22_HUMAN" 3 1078.5862 1.23 44274 9471 2 1078.585322 540.3004 D-3-phosphoglycerate dehydrogenase OS=Homo sapiens OX=9606 GN=PHGDH PE=1 SV=4 5.84 2094 - 5.14E+06 - - - -0.8354 - 2.014 0.483 - 572.9 1 2 0 -0.0009 10 0 0 0 2.42E+08 1.97E+08 - - - 4.5624 0.9994 221125_WJC_METTL3_EV_vs_WT_F04.09472.09472.2 0.00751 20-Aug R.EIGQSVDEVEK.L "sp|Q01082|SPTB2_HUMAN,tr|A0A087WUZ3|A0A087WUZ3_HUMAN" 2 1231.5932 1.25 44275 9472 2 1231.592712 616.8039 "Spectrin beta chain, non-erythrocytic 1 OS=Homo sapiens OX=9606 GN=SPTBN1 PE=1 SV=2" 4 2094.1 - 2.48E+06 - - - -0.406 - 1.456 0.39 - 188.5 1 2 0 -0.0005 11 0 0 0 3.74E+07 3.00E+07 - - - 2.9377 0.9998 221125_WJC_METTL3_EV_vs_WT_F04.09474.09474.2 1.46E-05 22-Sep R.EGVGPVEQEGVR[166.11].R sp|Q969Y2|GTPB3_HUMAN 1 1264.6287 1.56 44277 9474 2 1264.628892 633.3216 "tRNA modification GTPase GTPBP3, mitochondrial OS=Homo sapiens OX=9606 GN=GTPBP3 PE=1 SV=2" 4.25 2094.3 - 427438 - - - 0.1518 - 1.984 0.496 - 293.5 1 2 0 0.0002 12 0 0 0 1.69E+07 1.08E+07 - - - 4.507 0.9998 221125_WJC_METTL3_EV_vs_WT_F04.09475.09475.3 0.00256 Nov-36 R.VRPAYSLEPR.V "sp|Q96T37|RBM15_HUMAN,tr|A0A494C001|A0A494C001_HUMAN,tr|A0A499FJY3|A0A499FJY3_HUMAN,tr|A0A087WWP4|A0A087WWP4_HUMAN" 4 1186.6459 0.75 44278 9475 3 1186.644925 396.5559 RNA-binding protein 15 OS=Homo sapiens OX=9606 GN=RBM15 PE=1 SV=2 8.72 2094.4 - 392103 - - - -0.7846 - 2.072 0.342 - 155 1 2 0 -0.0009 10 0 0 0 2.43E+07 3.24E+07 - - - 4.4803 0.9996 221125_WJC_METTL3_EV_vs_WT_F04.09476.09476.2 0.000488 16-Aug M.APAEILNGK.E "sp|P11586|C1TC_HUMAN,tr|F5H2F4|F5H2F4_HUMAN,tr|V9GYY3|V9GYY3_HUMAN" 3 911.5076 0.13 44279 9476 2 911.505992 456.7611 "C-1-tetrahydrofolate synthase, cytoplasmic OS=Homo sapiens OX=9606 GN=MTHFD1 PE=1 SV=4" 6.05 2094.6 - 377279 - - - -1.7992 - 1.702 0.444 - 208.2 1 2 0 -0.0016 9 0 0 0 6.36E+06 4.98E+07 - - - 3.8584 0.9997 221125_WJC_METTL3_EV_vs_WT_F04.09483.09483.2 0.00282 16-Oct K.NSVEVALNK.L "sp|P54577|SYYC_HUMAN,tr|A0A6Q8PFX2|A0A6Q8PFX2_HUMAN" 2 972.524 0.62 44285 9483 2 972.524782 487.2693 "Tyrosine--tRNA ligase, cytoplasmic OS=Homo sapiens OX=9606 GN=YARS1 PE=1 SV=4" 6 2095.4 - 2.98E+06 - - - 0.7938 - 2.187 0.341 - 505.4 1 2 0 0.0008 9 0 0 0 4.64E+07 7.43E+07 - - - 3.8233 0.9999 221125_WJC_METTL3_EV_vs_WT_F04.09485.09485.2 0.000119 18-Nov K.TIQGDEEDLR.- "sp|P54920|SNAA_HUMAN,tr|M0R213|M0R213_HUMAN,tr|M0R0Y2|M0R0Y2_HUMAN" 3 1174.5466 1.18 44287 9485 2 1174.546442 588.2806 Alpha-soluble NSF attachment protein OS=Homo sapiens OX=9606 GN=NAPA PE=1 SV=3 3.92 2095.6 - 1.26E+06 - - - -0.1311 - 2.043 0.589 - 379.2 1 2 0 -0.0002 10 0 0 0 3.03E+07 2.57E+07 - - - 5.3855 0.9684 221125_WJC_METTL3_EV_vs_WT_F04.09489.09489.2 0.587 12-Jul K.IKEWYEK.H "sp|P13645|K1C10_HUMAN,tr|A0A1B0GVI3|A0A1B0GVI3_HUMAN" 2 994.5124 116.98 44290 9489 2 994.511785 498.2635 "Keratin, type I cytoskeletal 10 OS=Homo sapiens OX=9606 GN=KRT10 PE=1 SV=6" 6.14 2096 - 3.13E+07 - - - -0.6013 - 1.508 0.162 - 145.4 1 2 1 -0.0006 7 0 0 0 5.94E+08 5.08E+06 - - - 1.5389 0.9992 221125_WJC_METTL3_EV_vs_WT_F04.09493.09493.2 0.287 12-Sep K.HLLELNK.L "sp|Q9H3R5|CENPH_HUMAN,tr|B3KVZ3|B3KVZ3_HUMAN,tr|H0Y9E6|H0Y9E6_HUMAN" 3 865.5022 2.94 44293 9493 2 865.501538 433.7584 Centromere protein H OS=Homo sapiens OX=9606 GN=CENPH PE=1 SV=1 6.75 2096.4 - 1.21E+06 - - - -0.7094 - 1.652 0.275 - 227.6 1 2 0 -0.0006 7 0 0 0 5.43E+07 1.85E+07 - - - 2.6625 0.9998 221125_WJC_METTL3_EV_vs_WT_F04.09494.09494.2 0.000995 16-Nov R.RLEAVLASR.S sp|Q9BVI4|NOC4L_HUMAN 1 1013.5982 1.08 44294 9494 2 1013.597937 507.8064 Nucleolar complex protein 4 homolog OS=Homo sapiens OX=9606 GN=NOC4L PE=1 SV=1 9.6 2096.5 - 1.20E+06 - - - -0.2378 - 2.217 0.386 - 199.1 1 2 0 -0.0002 9 0 0 0 3.03E+07 2.81E+07 - - - 4.1952 0.9913 221125_WJC_METTL3_EV_vs_WT_F04.09495.09495.2 9.10E-06 22-Oct R.EGVGPVEQEGVR.R sp|Q969Y2|GTPB3_HUMAN 1 1254.6204 1.56 44295 9495 2 1254.629241 628.3175 "tRNA modification GTPase GTPBP3, mitochondrial OS=Homo sapiens OX=9606 GN=GTPBP3 PE=1 SV=2" 4.25 2096.6 - 980047 - - - 7.0228 - 2.126 0.512 - 432.8 1 2 0 0.0088 12 0 0 0 1.69E+07 1.08E+07 - - - 4.8044 1 221125_WJC_METTL3_EV_vs_WT_F04.09497.09497.2 4.07E-08 20-Sep K.GIMEEDEAC[160.03]GR.Q "sp|P14923|PLAK_HUMAN,tr|K7ERP3|K7ERP3_HUMAN,tr|C9JKY1|C9JKY1_HUMAN,tr|C9JK18|C9JK18_HUMAN,tr|C9JTX4|C9JTX4_HUMAN,tr|C9JPI2|C9JPI2_HUMAN,tr|C9J826|C9J826_HUMAN" 7 1265.5016 48.77 44297 9497 2 1265.50072 633.7581 Junction plakoglobin OS=Homo sapiens OX=9606 GN=JUP PE=1 SV=3 4 2096.8 - 807098 - - - -0.7246 - 1.962 0.686 - 306.7 1 2 0 -0.0009 11 0 0 0 3.68E+07 7.54E+05 - - - 5.9307 0.9396 221125_WJC_METTL3_EV_vs_WT_F04.09498.09498.3 0.0255 Nov-32 H.INHQPFLER[166.11].G "sp|P17844|DDX5_HUMAN,tr|A0A7I2V5F5|A0A7I2V5F5_HUMAN,tr|J3QRN5|J3QRN5_HUMAN,tr|A0A7I2V507|A0A7I2V507_HUMAN,tr|J3KTA4|J3KTA4_HUMAN,tr|A0A0G2JLI4|A0A0G2JLI4_HUMAN,tr|A0A7I2V2S0|A0A7I2V2S0_HUMAN,tr|J3QRQ7|J3QRQ7_HUMAN" 8 1162.6123 66.48 44298 9498 3 1162.611228 388.5447 Probable ATP-dependent RNA helicase DDX5 OS=Homo sapiens OX=9606 GN=DDX5 PE=1 SV=1 6.75 2096.9 - 565792 - - - -0.8894 - 1.891 0.288 - 154.6 1 1 0 -0.001 9 0 0 0 7.67E+08 1.15E+07 - - - 3.6707 0.9984 221125_WJC_METTL3_EV_vs_WT_F04.09500.09500.2 0.163 14-Jul R.TLQEQLEK.A "sp|Q9H307|PININ_HUMAN,tr|G3V5F0|G3V5F0_HUMAN,tr|G3V579|G3V579_HUMAN" 3 987.5237 2.72 44299 9500 2 987.523542 494.7691 Pinin OS=Homo sapiens OX=9606 GN=PNN PE=1 SV=5 4.53 2097.2 - 1.76E+06 - - - -0.1357 - 1.561 0.213 - 97.9 1 2 0 -0.0001 8 0 0 0 2.44E+08 8.98E+07 - - - 1.9573 0.9998 221125_WJC_METTL3_EV_vs_WT_F04.09502.09502.2 0.00297 14-Aug K.LQDEFENR.T "sp|P78344|IF4G2_HUMAN,tr|H0YEC5|H0YEC5_HUMAN,tr|H0Y3P2|H0Y3P2_HUMAN,tr|H0YCH5|H0YCH5_HUMAN,tr|H0YD77|H0YD77_HUMAN,tr|D3DQV9|D3DQV9_HUMAN" 6 1049.4778 2.23 44300 9502 2 1049.477765 525.7462 Eukaryotic translation initiation factor 4 gamma 2 OS=Homo sapiens OX=9606 GN=EIF4G2 PE=1 SV=1 4.14 2097.4 - 5.65E+06 - - - -0.0219 - 1.745 0.416 - 245.1 1 2 0 0 8 0 0 0 4.49E+08 2.02E+08 - - - 3.7927 0.9984 221125_WJC_METTL3_EV_vs_WT_F04.09503.09503.2 0.0212 14-Jun K.EFSGNPIK.V "sp|P35637|FUS_HUMAN,tr|H3BPE7|H3BPE7_HUMAN" 2 890.4498 0.96 44301 9503 2 890.450407 446.2322 RNA-binding protein FUS OS=Homo sapiens OX=9606 GN=FUS PE=1 SV=1 6.1 2097.4 - 2.70E+06 - - - 0.7019 - 1.183 0.344 - 189.9 1 2 0 0.0006 8 0 0 0 3.71E+08 3.85E+08 - - - 2.0884 0.9992 221125_WJC_METTL3_EV_vs_WT_F04.09504.09504.2 0.325 18-Sep K.SVFGETEEQK.C sp|P17509|HXB6_HUMAN 1 1152.5299 2 44302 9504 2 1152.530273 577.2722 Homeobox protein Hox-B6 OS=Homo sapiens OX=9606 GN=HOXB6 PE=1 SV=4 4.25 2097.5 - 1.65E+06 - - - 0.3384 - 1.647 0.288 - 195 1 2 0 0.0004 10 0 0 0 4.26E+07 2.13E+07 - - - 2.5608 0.9999 221125_WJC_METTL3_EV_vs_WT_F04.09506.09506.2 2.88E-07 18-Nov R.C[160.03]FGQQTNLDR.H "sp|Q03112|MECOM_HUMAN,sp|Q9HAZ2|PRD16_HUMAN,tr|E7EUL6|E7EUL6_HUMAN,tr|A0A0C3SFZ7|A0A0C3SFZ7_HUMAN,tr|D6RDW0|D6RDW0_HUMAN,tr|D6RFY3|D6RFY3_HUMAN,tr|H0YA13|H0YA13_HUMAN" 7 1237.551 0.01 44304 9506 2 1237.550715 619.7828 Histone-lysine N-methyltransferase MECOM OS=Homo sapiens OX=9606 GN=MECOM PE=1 SV=3 5.83 2097.7 - 675402 - - - -0.2061 - 2.12 0.588 - 394 1 2 0 -0.0003 10 0 0 0 1.25E+07 8.66E+08 - - - 5.4813 0.9985 221125_WJC_METTL3_EV_vs_WT_F04.09508.09508.2 0.0506 16-Sep K.KIIETPGIR.A "sp|P42704|LPPRC_HUMAN,tr|A0A804HI14|A0A804HI14_HUMAN,tr|A0A804HL40|A0A804HL40_HUMAN,tr|A0A804HKJ0|A0A804HKJ0_HUMAN,tr|A0A804HKR3|A0A804HKR3_HUMAN,tr|A0A804HIN4|A0A804HIN4_HUMAN,tr|A0A804HLG8|A0A804HLG8_HUMAN,tr|A0A804HHY9|A0A804HHY9_HUMAN,tr|A0A804HI40|A0A804HI40_HUMAN,tr|A0A804HJZ1|A0A804HJZ1_HUMAN,tr|A0A804HIQ7|A0A804HIQ7_HUMAN,tr|A0A804HK30|A0A804HK30_HUMAN,tr|A0A804HKI2|A0A804HKI2_HUMAN,tr|A0A804HJI0|A0A804HJI0_HUMAN,tr|A0A804HIG4|A0A804HIG4_HUMAN" 15 1025.6233 0.85 44306 9508 2 1025.624404 513.8189 "Leucine-rich PPR motif-containing protein, mitochondrial OS=Homo sapiens OX=9606 GN=LRPPRC PE=1 SV=3" 8.75 2098 - 391288 - - - 1.0472 - 1.788 0.209 - 319.2 1 2 0 0.0011 9 0 0 0 1.47E+07 1.73E+07 - - - 2.2655 0.9965 221125_WJC_METTL3_EV_vs_WT_F04.09509.09509.2 0.0439 16-Jul R.EYAIEPATK.W "sp|P31270|HXA11_HUMAN,tr|H0YIA6|H0YIA6_HUMAN" 2 1020.5128 1.68 44307 9509 2 1020.515412 511.2637 Homeobox protein Hox-A11 OS=Homo sapiens OX=9606 GN=HOXA11 PE=2 SV=2 4.53 2098.1 - 323104 - - - 2.582 - 1.396 0.318 - 160.1 1 2 0 0.0026 9 0 0 0 8.88E+06 5.30E+06 - - - 2.3541 0.8622 221125_WJC_METTL3_EV_vs_WT_F04.09510.09510.2 6.11 16-May K.LDVGNAEVK.L "sp|P51572|BAP31_HUMAN,tr|C9J0M4|C9J0M4_HUMAN,tr|C9JQ75|C9JQ75_HUMAN,tr|C9JSP1|C9JSP1_HUMAN,tr|C9JMD7|C9JMD7_HUMAN" 5 943.4975 0.07 44308 9510 2 943.498793 472.756 B-cell receptor-associated protein 31 OS=Homo sapiens OX=9606 GN=BCAP31 PE=1 SV=3 4.37 2098.2 - 282192 - - - 1.4118 - 1.022 0.047 - 58.3 4 2 0 0.0013 9 0 0 0 7.31E+06 9.80E+07 - - - -0.8183 0.9973 221125_WJC_METTL3_EV_vs_WT_F04.09512.09512.2 0.0145 18-Sep R.GEEILSGAQR.L "sp|P14868|SYDC_HUMAN,tr|H7BZ35|H7BZ35_HUMAN" 2 1058.5356 4.55 44309 9512 2 1058.535593 530.2751 "Aspartate--tRNA ligase, cytoplasmic OS=Homo sapiens OX=9606 GN=DARS1 PE=1 SV=2" 4.53 2098.5 - 4.62E+06 - - - -0.0416 - 1.607 0.162 - 198.5 1 2 0 0 10 0 0 0 1.61E+09 3.54E+08 - - - 1.5616 0.9721 221125_WJC_METTL3_EV_vs_WT_F04.09513.09513.2 0.4 12-Jun R.INIPPQR.G "sp|Q13283|G3BP1_HUMAN,tr|A0A7I2V5M7|A0A7I2V5M7_HUMAN,tr|A0A7P0P2U7|A0A7P0P2U7_HUMAN,tr|A0A7I2YQU8|A0A7I2YQU8_HUMAN,tr|A0A7I2V548|A0A7I2V548_HUMAN,tr|A0A7I2V565|A0A7I2V565_HUMAN,tr|A0A7I2YQN9|A0A7I2YQN9_HUMAN" 7 836.4868 1.42 44310 9513 2 836.486711 419.2507 Ras GTPase-activating protein-binding protein 1 OS=Homo sapiens OX=9606 GN=G3BP1 PE=1 SV=1 9.75 2098.6 - 512218 - - - -0.1506 - 1.327 0 - 158.3 1 2 0 -0.0001 7 0 0 0 3.97E+07 2.79E+07 - - - -0.0626 0.9989 221125_WJC_METTL3_EV_vs_WT_F04.09514.09514.2 0.0672 14-Jul K.LQDEFENR[166.11].T "sp|P78344|IF4G2_HUMAN,tr|H0YEC5|H0YEC5_HUMAN,tr|H0Y3P2|H0Y3P2_HUMAN,tr|H0YCH5|H0YCH5_HUMAN,tr|H0YD77|H0YD77_HUMAN,tr|D3DQV9|D3DQV9_HUMAN" 6 1059.4861 2.28 44311 9514 2 1059.486039 530.7503 Eukaryotic translation initiation factor 4 gamma 2 OS=Homo sapiens OX=9606 GN=EIF4G2 PE=1 SV=1 4.14 2098.6 - 4.62E+06 - - - -0.0179 - 1.622 0.242 - 161.8 1 2 0 0 8 0 0 0 4.41E+08 1.93E+08 - - - 2.2871 0.9999 221125_WJC_METTL3_EV_vs_WT_F04.09519.09519.2 0.0145 14/26 K.ALSAVSAQAAAAQK.N "sp|O00268|TAF4_HUMAN,tr|V9GY14|V9GY14_HUMAN,tr|A0A0G2JRY5|A0A0G2JRY5_HUMAN" 3 1285.699 1.73 44314 9519 2 1285.698726 643.8568 Transcription initiation factor TFIID subunit 4 OS=Homo sapiens OX=9606 GN=TAF4 PE=1 SV=2 8.8 2099.3 - 267501 - - - -0.224 - 3.079 0.375 - 793 1 2 0 -0.0003 14 0 0 0 5.46E+07 3.15E+07 - - - 4.6328 0.999 221125_WJC_METTL3_EV_vs_WT_F04.09521.09521.2 0.0576 14-Jul K.DYIEC[160.03]AEK.L "sp|O75635|SPB7_HUMAN,tr|C9JM00|C9JM00_HUMAN,tr|A0A1B0GX82|A0A1B0GX82_HUMAN,tr|C9JA68|C9JA68_HUMAN" 4 1026.4328 169.1 44316 9521 2 1026.433556 514.2237 Serpin B7 OS=Homo sapiens OX=9606 GN=SERPINB7 PE=1 SV=1 4.14 2099.5 - 557441 - - - 0.7248 - 1.279 0.368 - 177.3 1 2 0 0.0007 8 0 0 0 9.66E+06 5.71E+04 - - - 2.501 0.9997 221125_WJC_METTL3_EV_vs_WT_F04.09522.09522.2 9.53E-07 22-Sep K.LGSTEVASNVPK[136.11].V "sp|Q9Y5A9|YTHD2_HUMAN,tr|S4R3V3|S4R3V3_HUMAN" 2 1208.6492 1.46 44317 9522 2 1208.651515 605.3319 YTH domain-containing family protein 2 OS=Homo sapiens OX=9606 GN=YTHDF2 PE=1 SV=2 6 2099.7 - 401061 - - - 1.9013 - 2.249 0.492 - 227.8 1 2 0 0.0023 12 0 0 0 2.69E+09 1.84E+09 - - - 4.8067 0.9986 221125_WJC_METTL3_EV_vs_WT_F04.09524.09524.2 0.000483 13/18 R.YPDGIISK[136.11]PK[136.11].N sp|Q86U44|MTA70_HUMAN 1 1132.6463 0 44318 9524 2 1132.648556 567.3304 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 8.5 2099.9 - 1.17E+06 - - - 1.983 - 2.009 0.251 - 582.9 1 2 0 0.0022 10 0 0 0 7.80E+04 3.35E+07 - - - 2.8415 0.9998 221125_WJC_METTL3_EV_vs_WT_F04.09526.09526.3 0.0328 Oct-36 R.VR[166.11]PAYSLEPR[166.11].V "sp|Q96T37|RBM15_HUMAN,tr|A0A494C001|A0A494C001_HUMAN,tr|A0A499FJY3|A0A499FJY3_HUMAN,tr|A0A087WWP4|A0A087WWP4_HUMAN" 4 1206.6624 0.76 44319 9526 3 1206.661774 403.2281 RNA-binding protein 15 OS=Homo sapiens OX=9606 GN=RBM15 PE=1 SV=2 8.72 2100.1 - 1.27E+06 - - - -0.5155 - 2.097 0.368 - 188 1 2 0 -0.0006 10 0 0 0 2.82E+07 3.70E+07 - - - 4.8053 0.9999 221125_WJC_METTL3_EV_vs_WT_F04.09528.09528.2 5.71E-05 22-Nov K.LGSTEVASNVPK.V "sp|Q9Y5A9|YTHD2_HUMAN,tr|S4R3V3|S4R3V3_HUMAN" 2 1200.635 1.46 44321 9528 2 1200.635047 601.3248 YTH domain-containing family protein 2 OS=Homo sapiens OX=9606 GN=YTHDF2 PE=1 SV=2 6 2100.3 - 1.11E+06 - - - 0.025 - 2.249 0.517 - 350.5 1 2 0 0 12 0 0 0 2.69E+09 1.84E+09 - - - 4.9921 0.9998 221125_WJC_METTL3_EV_vs_WT_F04.09529.09529.2 0.0851 20-Nov K.EVELAPGASDR.V "sp|P22735|TGM1_HUMAN,tr|H0YMQ8|H0YMQ8_HUMAN" 2 1142.5568 43.7 44322 9529 2 1142.557105 572.2857 Protein-glutamine gamma-glutamyltransferase K OS=Homo sapiens OX=9606 GN=TGM1 PE=1 SV=4 4.14 2100.4 - 808060 - - - 0.2958 - 2.116 0.384 - 376.6 1 2 0 0.0003 11 0 0 0 1.62E+07 3.71E+05 - - - 3.9048 0.999 221125_WJC_METTL3_EV_vs_WT_F04.09532.09532.2 0.000137 22-Sep R.LEVSPEAQPTAR[166.11].L sp|Q6WKZ4|RFIP1_HUMAN 1 1306.6756 2.79 44325 9532 2 1306.679245 654.3451 Rab11 family-interacting protein 1 OS=Homo sapiens OX=9606 GN=RAB11FIP1 PE=1 SV=3 4.53 2100.8 - 150775 - - - 2.7513 - 1.928 0.408 - 269 1 2 0 0.0036 12 0 0 0 8.03E+06 2.88E+06 - - - 3.7807 0.9854 221125_WJC_METTL3_EV_vs_WT_F04.09535.09535.3 3.18 15/32 R.LAELSDYR[166.11]R[166.11].L sp|Q96PK6|RBM14_HUMAN 1 1141.5995 0.001 44326 9535 3 1141.599179 381.5404 RNA-binding protein 14 OS=Homo sapiens OX=9606 GN=RBM14 PE=1 SV=2 6.07 2101.2 - 1.17E+06 - - - -0.2479 - 2.07 0.076 - 304.8 1 2 0 -0.0003 9 0 0 0 0.00E+00 8.67E+08 - - - 1.5799 0.9998 221125_WJC_METTL3_EV_vs_WT_F04.09536.09536.2 0.00256 22-Nov K.AVEIVTSTSAAK[136.11].T sp|Q14966|ZN638_HUMAN 1 1183.654 0.9 44327 9536 2 1183.65395 592.8343 Zinc finger protein 638 OS=Homo sapiens OX=9606 GN=ZNF638 PE=1 SV=2 6.05 2101.3 - 967180 - - - -0.0152 - 2.179 0.379 - 347.7 1 2 0 0 12 0 0 0 1.84E+07 2.03E+07 - - - 3.8896 0.9996 221125_WJC_METTL3_EV_vs_WT_F04.09537.09537.2 0.0107 16-Sep K.ALDLDSSC[160.03]K[136.11].E "sp|P31948|STIP1_HUMAN,tr|H0YGI8|H0YGI8_HUMAN" 2 1015.4736 1.33 44328 9537 2 1015.473696 508.7441 Stress-induced-phosphoprotein 1 OS=Homo sapiens OX=9606 GN=STIP1 PE=1 SV=1 4.21 2101.4 - 1.53E+06 - - - 0.1329 - 1.881 0.329 - 289 1 2 0 0.0001 9 0 0 0 6.91E+07 5.19E+07 - - - 3.2988 0.9584 221125_WJC_METTL3_EV_vs_WT_F04.09538.09538.3 0.0257 Nov-32 F.LFC[160.03]SEYR[166.11]PK[136.11].L "sp|P09429|HMGB1_HUMAN,sp|P23497|SP100_HUMAN,tr|Q5T7C4|Q5T7C4_HUMAN" 3 1216.6029 0.14 44329 9538 3 1216.603353 406.5416 High mobility group protein B1 OS=Homo sapiens OX=9606 GN=HMGB1 PE=1 SV=3 8.2 2101.5 - 494780 - - - 0.3321 - 2.144 0.281 - 171 1 1 0 0.0004 9 0 0 0 1.68E+06 1.21E+07 - - - 3.9713 0.9991 221125_WJC_METTL3_EV_vs_WT_F04.09539.09539.2 0.00685 16-Sep R.DGAASLSYR.V sp|Q8TEM1|PO210_HUMAN 1 938.4458 0.4 44330 9539 2 938.44494 470.2302 Nuclear pore membrane glycoprotein 210 OS=Homo sapiens OX=9606 GN=NUP210 PE=1 SV=3 5.84 2101.6 - 441015 - - - -0.8738 - 2.028 0.197 - 408.7 1 2 0 -0.0008 9 0 0 0 2.88E+07 7.19E+07 - - - 2.5413 0.9926 221125_WJC_METTL3_EV_vs_WT_F04.09544.09544.2 0.57 16-Jul R.R[166.11]LEAVLASR[166.11].S sp|Q9BVI4|NOC4L_HUMAN 1 1033.6147 1.08 44333 9544 2 1033.614951 517.8146 Nucleolar complex protein 4 homolog OS=Homo sapiens OX=9606 GN=NOC4L PE=1 SV=1 9.6 2102.2 - 985786 - - - 0.2254 - 1.064 0.22 - 77.7 1 2 0 0.0002 9 0 0 0 3.03E+07 2.81E+07 - - - 0.8453 0.9998 221125_WJC_METTL3_EV_vs_WT_F04.09545.09545.2 0.0348 16-Sep K.ALDLDSSC[160.03]K.E "sp|P31948|STIP1_HUMAN,tr|H0YGI8|H0YGI8_HUMAN" 2 1007.4594 1.25 44334 9545 2 1007.459044 504.737 Stress-induced-phosphoprotein 1 OS=Homo sapiens OX=9606 GN=STIP1 PE=1 SV=1 4.21 2102.3 - 2.15E+06 - - - -0.3147 - 1.982 0.397 - 235.2 1 2 0 -0.0003 9 0 0 0 7.14E+07 5.71E+07 - - - 3.9523 1 221125_WJC_METTL3_EV_vs_WT_F04.09546.09546.2 3.87E-08 16/26 K.ALSAVSAQAAAAQK[136.11].N "sp|O00268|TAF4_HUMAN,tr|V9GY14|V9GY14_HUMAN,tr|A0A0G2JRY5|A0A0G2JRY5_HUMAN" 3 1293.7132 1.73 44335 9546 2 1293.713906 647.8639 Transcription initiation factor TFIID subunit 4 OS=Homo sapiens OX=9606 GN=TAF4 PE=1 SV=2 8.8 2102.4 - 1.03E+06 - - - 0.5349 - 3.219 0.527 - 1044.7 1 2 0 0.0007 14 0 0 0 5.46E+07 3.15E+07 - - - 5.8669 0.9999 221125_WJC_METTL3_EV_vs_WT_F04.09547.09547.3 0.0445 19/40 R.FATHAAALSVR[166.11].N sp|P23246|SFPQ_HUMAN 1 1152.6279 0.4 44336 9547 3 1152.630926 385.2166 "Splicing factor, proline- and glutamine-rich OS=Homo sapiens OX=9606 GN=SFPQ PE=1 SV=2" 9.76 2102.5 - 718284 - - - 2.6149 - 2.885 0.495 - 386.6 1 2 0 0.003 11 0 0 0 1.51E+08 3.77E+08 - - - 7.0679 0.9371 221125_WJC_METTL3_EV_vs_WT_F04.09551.09551.2 0.0294 16-Aug K.TAVC[160.03]DIPPR.G "sp|P04350|TBB4A_HUMAN,sp|Q9BVA1|TBB2B_HUMAN,sp|A6NNZ2|TBB8B_HUMAN,sp|P07437|TBB5_HUMAN,sp|Q13885|TBB2A_HUMAN,sp|P68371|TBB4B_HUMAN,sp|Q3ZCM7|TBB8_HUMAN,tr|Q5ST81|Q5ST81_HUMAN,tr|Q5JP53|Q5JP53_HUMAN,tr|A0A075B736|A0A075B736_HUMAN,tr|Q5SQY0|Q5SQY0_HUMAN" 11 1027.5121 4.87 44338 9551 2 1028.516071 514.7633 Tubulin beta-4A chain OS=Homo sapiens OX=9606 GN=TUBB4A PE=1 SV=2 5.5 2103 - 988279 - - - 977.1233 - 1.496 0.294 - 227.4 1 2 0 1.004 9 0 0 0 9.81E+07 2.01E+07 - - - 2.0625 0.9994 221125_WJC_METTL3_EV_vs_WT_F04.09552.09552.2 0.000776 16-Oct R.DGAASLSYR[166.11].V sp|Q8TEM1|PO210_HUMAN 1 948.454 2.12 44339 9552 2 948.454118 475.2343 Nuclear pore membrane glycoprotein 210 OS=Homo sapiens OX=9606 GN=NUP210 PE=1 SV=3 5.84 2103.1 - 599487 - - - 0.0928 - 1.92 0.269 - 512.1 1 2 0 0.0001 9 0 0 0 6.07E+07 2.87E+07 - - - 2.915 0.9998 221125_WJC_METTL3_EV_vs_WT_F04.09554.09554.2 0.00242 20-Aug K.IYIDSNNNPER.F "sp|Q00610|CLH1_HUMAN,tr|A0A087WVQ6|A0A087WVQ6_HUMAN" 2 1333.6262 0.4 44341 9554 2 1333.625508 667.8204 Clathrin heavy chain 1 OS=Homo sapiens OX=9606 GN=CLTC PE=1 SV=5 4.37 2103.4 - 447260 - - - -0.5511 - 1.773 0.49 - 171.9 1 2 0 -0.0007 11 0 0 0 2.85E+07 7.05E+07 - - - 4.2091 0.9892 221125_WJC_METTL3_EV_vs_WT_F04.09560.09560.2 0.292 14-Aug R.TLQEQLEK[136.11].A "sp|Q9H307|PININ_HUMAN,tr|G3V5F0|G3V5F0_HUMAN,tr|G3V579|G3V579_HUMAN" 3 995.5379 2.68 44345 9560 2 995.540937 498.7762 Pinin OS=Homo sapiens OX=9606 GN=PNN PE=1 SV=5 4.53 2104.1 - 6.16E+06 - - - 3.0747 - 1.306 0.251 - 166.6 1 2 0 0.0031 8 0 0 0 2.39E+08 8.90E+07 - - - 1.6991 0.9526 221125_WJC_METTL3_EV_vs_WT_F04.09561.09561.2 0.0856 22-Jun K.QPGNETADTVLK[136.11].K sp|P61758|PFD3_HUMAN 1 1279.6499 0.56 44346 9561 2 1279.64341 640.8322 Prefoldin subunit 3 OS=Homo sapiens OX=9606 GN=VBP1 PE=1 SV=4 4.37 2104.2 - 181168 - - - -5.1069 - 1.183 0.294 - 94.9 1 2 0 -0.0065 12 0 0 0 2.14E+07 3.82E+07 - - - 1.6526 0.9977 221125_WJC_METTL3_EV_vs_WT_F04.09564.09564.2 0.135 12-Jul K.WQQFNNR[166.11].A sp|O75940|SPF30_HUMAN 1 1001.4707 1.09 44347 9564 2 1001.470219 501.7426 Survival of motor neuron-related-splicing factor 30 OS=Homo sapiens OX=9606 GN=SMNDC1 PE=1 SV=1 9.75 2104.6 - 2.22E+06 - - - -0.4633 - 1.146 0.303 - 177 1 2 0 -0.0005 7 0 0 0 4.49E+07 4.11E+07 - - - 1.7106 0.9761 221125_WJC_METTL3_EV_vs_WT_F04.09566.09566.2 1.49 12-Jul K.SEISELR.R "sp|Q04695|K1C17_HUMAN,sp|P02533|K1C14_HUMAN,tr|F5GWP8|F5GWP8_HUMAN" 3 832.429 2.24 44349 9566 2 832.428626 417.2218 "Keratin, type I cytoskeletal 17 OS=Homo sapiens OX=9606 GN=KRT17 PE=1 SV=2" 4.53 2104.8 - 958393 - - - -0.5057 - 1.376 0.001 - 294 1 2 0 -0.0004 7 0 0 0 4.74E+07 2.12E+07 - - - 0.0596 0.9997 221125_WJC_METTL3_EV_vs_WT_F04.09567.09567.2 0.000819 13/20 R.FATHAAALSVR[166.11].N sp|P23246|SFPQ_HUMAN 1 1152.6279 0.12 44350 9567 2 1152.625596 577.3212 "Splicing factor, proline- and glutamine-rich OS=Homo sapiens OX=9606 GN=SFPQ PE=1 SV=2" 9.76 2105 - 585933 - - - -2.0093 - 2.11 0.482 - 647.5 1 2 0 -0.0023 11 0 0 0 6.70E+06 5.78E+07 - - - 4.6203 0.9998 221125_WJC_METTL3_EV_vs_WT_F04.09568.09568.2 2.97E-05 20-Oct R.IGGGWGNSDAR[166.11].Y "sp|Q8NDV7|TNR6A_HUMAN,tr|H7C269|H7C269_HUMAN,tr|H3BRT3|H3BRT3_HUMAN" 3 1098.5082 18.32 44351 9568 2 1098.508207 550.2614 Trinucleotide repeat-containing gene 6A protein OS=Homo sapiens OX=9606 GN=TNRC6A PE=1 SV=2 5.84 2105.1 - 395213 - - - 0.0155 - 1.821 0.48 - 250.8 1 2 0 0 11 0 0 0 1.42E+08 7.73E+06 - - - 4.2078 0.9998 221125_WJC_METTL3_EV_vs_WT_F04.09569.09569.2 7.65E-06 22-Nov K.IVGPSGAAVPC[160.03]K[136.11].V "sp|P21333|FLNA_HUMAN,tr|A0A7P0NMY4|A0A7P0NMY4_HUMAN,tr|Q60FE5|Q60FE5_HUMAN" 3 1162.626 6.98 44352 9569 2 1162.624131 582.3203 Filamin-A OS=Homo sapiens OX=9606 GN=FLNA PE=1 SV=4 8.22 2105.2 - 279261 - - - -1.5895 - 2.112 0.479 - 248.6 1 2 0 -0.0018 12 0 0 0 2.17E+08 3.11E+07 - - - 4.5455 0.999 221125_WJC_METTL3_EV_vs_WT_F04.09571.09571.2 0.000133 18-Jul R.TFYSC[160.03]TTEGR.Q sp|P02751|FINC_HUMAN 1 1220.5132 5.26 44353 9571 2 1220.517205 611.2639 Fibronectin OS=Homo sapiens OX=9606 GN=FN1 PE=1 SV=5 5.66 2105.6 - 143213 - - - 3.2912 - 1.529 0.54 - 132.9 1 2 0 0.004 10 0 0 0 2.83E+06 5.38E+05 - - - 4.2134 0.9566 221125_WJC_METTL3_EV_vs_WT_F04.09573.09573.2 1.29 16-May R.LAELSDYRR.L sp|Q96PK6|RBM14_HUMAN 1 1121.5829 1.31 44354 9573 2 1121.586717 561.7987 RNA-binding protein 14 OS=Homo sapiens OX=9606 GN=RBM14 PE=1 SV=2 6.07 2105.8 - 5.09E+06 - - - 3.3836 - 1.229 0.179 - 65.5 2 2 0 0.0038 9 0 0 0 2.54E+08 1.94E+08 - - - 0.824 0.9985 221125_WJC_METTL3_EV_vs_WT_F04.09574.09574.2 0.0157 16-Sep K.AVQEIMQEK.A "sp|P22102|PUR2_HUMAN,tr|F8WD69|F8WD69_HUMAN,tr|H7C366|H7C366_HUMAN,tr|C9JTV6|C9JTV6_HUMAN,tr|C9JBJ1|C9JBJ1_HUMAN" 5 1074.5379 0.84 44355 9574 2 1074.536755 538.2762 Trifunctional purine biosynthetic protein adenosine-3 OS=Homo sapiens OX=9606 GN=GART PE=1 SV=1 4.53 2105.9 - 1.54E+06 - - - -1.1084 - 1.772 0.208 - 266.6 1 2 0 -0.0012 9 0 0 0 4.09E+07 4.86E+07 - - - 2.2321 0.9998 221125_WJC_METTL3_EV_vs_WT_F04.09580.09580.2 0.00045 22-Aug K.QPGNETADTVLK.K sp|P61758|PFD3_HUMAN 1 1271.6357 0.56 44361 9580 2 1271.634076 636.8251 Prefoldin subunit 3 OS=Homo sapiens OX=9606 GN=VBP1 PE=1 SV=4 4.37 2106.5 - 139023 - - - -1.3125 - 1.861 0.551 - 119.7 1 2 0 -0.0017 12 0 0 0 2.14E+07 3.82E+07 - - - 4.7444 0.9999 221125_WJC_METTL3_EV_vs_WT_F04.09586.09586.3 0.0146 Dec-36 R.GGDLMAYDR[166.11]R[166.11].G "sp|P61978|HNRPK_HUMAN,tr|Q5T6W2|Q5T6W2_HUMAN" 2 1172.5511 1.18 44365 9586 3 1172.548153 391.8577 Heterogeneous nuclear ribonucleoprotein K OS=Homo sapiens OX=9606 GN=HNRNPK PE=1 SV=1 5.96 2107.1 - 1.28E+06 - - - -2.5398 - 2.178 0.453 - 294.4 1 2 0 -0.003 10 0 0 0 1.44E+08 1.22E+08 - - - 5.863 0.9942 221125_WJC_METTL3_EV_vs_WT_F04.09589.09589.2 0.131 14-Jun R.DVSEELSR[166.11].Q sp|P40222|TXLNA_HUMAN 1 943.4486 1.25 44368 9589 2 943.446489 472.7316 Alpha-taxilin OS=Homo sapiens OX=9606 GN=TXLNA PE=1 SV=3 4.14 2107.4 - 537134 - - - -2.2481 - 1.247 0.27 - 98.9 1 2 0 -0.0021 8 0 0 0 6.90E+07 5.50E+07 - - - 1.7003 0.9949 221125_WJC_METTL3_EV_vs_WT_F04.09591.09591.2 0.00825 16-Jul R.SGDLPYDGR.L "sp|Q86X29|LSR_HUMAN,tr|S4R3V8|S4R3V8_HUMAN" 2 978.4407 1.71 44370 9591 2 978.437191 490.2276 Lipolysis-stimulated lipoprotein receptor OS=Homo sapiens OX=9606 GN=LSR PE=1 SV=4 4.21 2107.7 - 306059 - - - -3.5597 - 1.396 0.354 - 228.7 1 2 0 -0.0035 9 0 0 0 7.64E+06 4.46E+06 - - - 2.6197 0.9994 221125_WJC_METTL3_EV_vs_WT_F04.09593.09593.2 0.00229 16-Oct K.AVQEIMQEK[136.11].A "sp|P22102|PUR2_HUMAN,tr|F8WD69|F8WD69_HUMAN,tr|H7C366|H7C366_HUMAN,tr|C9JTV6|C9JTV6_HUMAN,tr|C9JBJ1|C9JBJ1_HUMAN" 5 1082.5521 0.85 44371 9593 2 1082.552919 542.2833 Trifunctional purine biosynthetic protein adenosine-3 OS=Homo sapiens OX=9606 GN=GART PE=1 SV=1 4.53 2107.9 - 1.05E+06 - - - 0.7141 - 1.733 0.323 - 308.3 1 2 0 0.0008 9 0 0 0 4.13E+07 4.86E+07 - - - 3.0172 0.9999 221125_WJC_METTL3_EV_vs_WT_F04.09595.09595.2 0.000188 20-Nov R.ISSVLAGGSC[160.03]R.A "sp|P02533|K1C14_HUMAN,sp|P08779|K1C16_HUMAN,tr|K7ENV3|K7ENV3_HUMAN" 3 1105.555 6488.92 44372 9595 2 1105.553826 553.7848 "Keratin, type I cytoskeletal 14 OS=Homo sapiens OX=9606 GN=KRT14 PE=1 SV=4" 8.25 2108.1 - 3.26E+08 - - - -1.0556 - 2.232 0.515 - 485.9 1 2 0 -0.0012 11 0 0 0 9.16E+09 1.41E+06 - - - 5.0165 0.9979 221125_WJC_METTL3_EV_vs_WT_F04.09596.09596.2 0.0724 14-Aug K.VVDPFSKK.D "sp|P61247|RS3A_HUMAN,tr|H0Y8L7|H0Y8L7_HUMAN,tr|D6RI02|D6RI02_HUMAN,tr|H0Y9Y4|H0Y9Y4_HUMAN,tr|E9PFI5|E9PFI5_HUMAN" 5 918.5175 1.51 44373 9596 2 918.516147 460.266 40S ribosomal protein S3a OS=Homo sapiens OX=9606 GN=RPS3A PE=1 SV=2 8.56 2108.2 - 1.64E+06 - - - -1.4382 - 1.2 0.339 - 171.4 1 2 0 -0.0013 8 0 0 0 7.66E+07 5.08E+07 - - - 2.0943 0.9222 221125_WJC_METTL3_EV_vs_WT_F04.09597.09597.2 0.247 16-Oct K.TVISQSLSK[136.11].Y sp|P38606|VATA_HUMAN 1 969.5586 1.85 44374 9597 2 969.552507 485.7866 V-type proton ATPase catalytic subunit A OS=Homo sapiens OX=9606 GN=ATP6V1A PE=1 SV=2 8.41 2108.3 - 742222 - - - -6.2956 - 1.688 0.181 - 266.1 1 2 0 -0.0061 9 0 0 0 2.41E+07 1.30E+07 - - - 1.8906 0.9999 221125_WJC_METTL3_EV_vs_WT_F04.09602.09602.2 0.0179 22-Dec R.TSLSAEDAEVTK.A sp|Q9P2D1|CHD7_HUMAN 1 1249.6038 1.62 44377 9602 2 1249.60338 625.8092 Chromodomain-helicase-DNA-binding protein 7 OS=Homo sapiens OX=9606 GN=CHD7 PE=1 SV=3 4.14 2109 - 557590 - - - -0.3177 - 2.537 0.529 - 336.1 1 2 0 -0.0004 12 0 0 0 7.98E+06 4.94E+06 - - - 5.3976 0.9923 221125_WJC_METTL3_EV_vs_WT_F04.09603.09603.2 0.208 16-Sep R.EQILGDEAR[166.11].A "sp|Q13724|MOGS_HUMAN,tr|A0A3B3IS52|A0A3B3IS52_HUMAN,tr|A0A3B3IRK6|A0A3B3IRK6_HUMAN,tr|A0A3B3IRW2|A0A3B3IRW2_HUMAN" 4 1039.5174 1.82 44378 9603 2 1039.513357 520.766 Mannosyl-oligosaccharide glucosidase OS=Homo sapiens OX=9606 GN=MOGS PE=1 SV=5 4.14 2109 - 2.08E+06 - - - -3.8489 - 1.714 0.248 - 374.3 1 2 0 -0.004 9 0 0 0 7.20E+07 3.95E+07 - - - 2.4303 0.9974 221125_WJC_METTL3_EV_vs_WT_F04.09604.09604.2 0.0646 14-Jun R.AQYDELAR.K "sp|P05783|K1C18_HUMAN,tr|F8VZY9|F8VZY9_HUMAN" 2 964.4614 2.39 44379 9604 2 964.462217 483.238 "Keratin, type I cytoskeletal 18 OS=Homo sapiens OX=9606 GN=KRT18 PE=1 SV=2" 4.37 2109.2 - 597232 - - - 0.8367 - 1.238 0.278 - 159.3 1 2 0 0.0008 8 0 0 0 1.44E+07 6.00E+06 - - - 1.738 0.9965 221125_WJC_METTL3_EV_vs_WT_F04.09605.09605.2 0.00394 16-Jul K.DYSSGFGGK[136.11].Y sp|Q14247|SRC8_HUMAN 1 924.4069 0.63 44380 9605 2 924.407916 463.2107 Src substrate cortactin OS=Homo sapiens OX=9606 GN=CTTN PE=1 SV=2 5.83 2109.3 - 411887 - - - 1.1413 - 1.158 0.292 - 141 1 2 0 0.0011 9 0 0 0 8.27E+06 1.31E+07 - - - 1.6218 0.9807 221125_WJC_METTL3_EV_vs_WT_F04.09610.09610.2 1.22 12-Jul K.WQQFNNR.A sp|O75940|SPF30_HUMAN 1 991.4624 1.08 44383 9610 2 991.459693 496.7385 Survival of motor neuron-related-splicing factor 30 OS=Homo sapiens OX=9606 GN=SMNDC1 PE=1 SV=1 9.75 2109.9 - 1.78E+06 - - - -2.7434 - 1.496 0.101 - 210.3 1 2 0 -0.0027 7 0 0 0 4.49E+07 4.15E+07 - - - 1.0624 0.9997 221125_WJC_METTL3_EV_vs_WT_F04.09612.09612.2 2.00E-07 20-Nov R.QPPSQGLGYPK[136.11].Y sp|P48634|PRC2A_HUMAN 1 1178.6175 1.07 44385 9612 2 1178.618682 590.316 Protein PRRC2A OS=Homo sapiens OX=9606 GN=PRRC2A PE=1 SV=3 8.59 2110.2 - 885518 - - - 0.9834 - 1.916 0.426 - 367.8 1 2 0 0.0012 11 0 0 0 6.49E+07 6.07E+07 - - - 3.9461 0.9972 221125_WJC_METTL3_EV_vs_WT_F04.09615.09615.3 0.0239 Aug-44 R.YPLAAAAERPPR.L sp|Q7Z5L9|I2BP2_HUMAN 1 1310.7095 1.57 44388 9615 3 1310.708494 437.9104 Interferon regulatory factor 2-binding protein 2 OS=Homo sapiens OX=9606 GN=IRF2BP2 PE=1 SV=2 8.75 2110.6 - 433387 - - - -0.782 - 1.549 0.256 - 86 1 2 0 -0.001 12 0 0 0 8.19E+07 5.23E+07 - - - 2.6069 0.9964 221125_WJC_METTL3_EV_vs_WT_F04.09620.09620.2 0.372 18-Sep R.GGDLMAYDR[166.11]R[166.11].G "sp|P61978|HNRPK_HUMAN,tr|Q5T6W2|Q5T6W2_HUMAN" 2 1172.5511 1.48 44391 9620 2 1172.548736 587.2828 Heterogeneous nuclear ribonucleoprotein K OS=Homo sapiens OX=9606 GN=HNRNPK PE=1 SV=1 5.96 2111.2 - 1.23E+06 - - - -2.0426 - 1.318 0.292 - 221 1 2 0 -0.0024 10 0 0 0 2.34E+07 1.58E+07 - - - 1.9677 0.9992 221125_WJC_METTL3_EV_vs_WT_F04.09621.09621.2 0.0259 16-Aug K.LEEQDEFEK.L "sp|Q9NTJ5|SAC1_HUMAN,tr|E9PGZ4|E9PGZ4_HUMAN,tr|A0A5F9ZHN7|A0A5F9ZHN7_HUMAN,tr|C9JV50|C9JV50_HUMAN" 4 1165.5139 1.64 44392 9621 2 1165.511537 583.7642 Phosphatidylinositol-3-phosphatase SAC1 OS=Homo sapiens OX=9606 GN=SACM1L PE=1 SV=2 3.91 2111.4 - 870698 - - - -2.0266 - 1.779 0.364 - 197.3 1 2 0 -0.0024 9 0 0 0 2.65E+07 1.62E+07 - - - 3.3953 0.9995 221125_WJC_METTL3_EV_vs_WT_F04.09630.09630.2 0.00587 18-Sep R.GDTVATLSER[166.11].V sp|P22102|PUR2_HUMAN 1 1057.5279 0.36 44397 9630 2 1057.526933 529.7712 Trifunctional purine biosynthetic protein adenosine-3 OS=Homo sapiens OX=9606 GN=GART PE=1 SV=1 4.37 2112.5 - 1.21E+06 - - - -0.9361 - 1.818 0.326 - 352.6 1 2 0 -0.001 10 0 0 0 8.69E+06 2.38E+07 - - - 3.117 0.9997 221125_WJC_METTL3_EV_vs_WT_F04.09631.09631.2 8.07E-05 18-Aug R.VNEVNQFAAK[136.11].L "sp|Q13813|SPTN1_HUMAN,tr|A0A0D9SF54|A0A0D9SF54_HUMAN,tr|A0A0D9SGF6|A0A0D9SGF6_HUMAN" 3 1126.5862 1.64 44398 9631 2 1126.584068 564.3004 "Spectrin alpha chain, non-erythrocytic 1 OS=Homo sapiens OX=9606 GN=SPTAN1 PE=1 SV=3" 5.97 2112.6 - 1.33E+06 - - - -1.9129 - 1.977 0.487 - 124.3 1 2 0 -0.0022 10 0 0 0 5.65E+07 3.45E+07 - - - 4.5398 1 221125_WJC_METTL3_EV_vs_WT_F04.09633.09633.2 1.34E-07 15/26 K.TPTSSPASSPLVAK[136.11].K sp|Q14684|RRP1B_HUMAN 1 1349.7282 0.85 44400 9633 2 1349.7273 675.8714 Ribosomal RNA processing protein 1 homolog B OS=Homo sapiens OX=9606 GN=RRP1B PE=1 SV=3 8.41 2112.8 - 507696 - - - -0.6638 - 3.068 0.591 - 727.1 1 2 0 -0.0009 14 0 0 0 1.44E+07 1.69E+07 - - - 6.219 0.9998 221125_WJC_METTL3_EV_vs_WT_F04.09636.09636.2 4.68E-07 16-Sep K.DVDAAYMNK.V "sp|P48668|K2C6C_HUMAN,sp|P04259|K2C6B_HUMAN,sp|P13647|K2C5_HUMAN,sp|Q14CN4|K2C72_HUMAN,sp|O95678|K2C75_HUMAN,sp|P02538|K2C6A_HUMAN,tr|F8W0C6|F8W0C6_HUMAN,tr|H0YIN9|H0YIN9_HUMAN" 8 1025.4488 1449.88 44401 9636 2 1025.447894 513.7317 "Keratin, type II cytoskeletal 6C OS=Homo sapiens OX=9606 GN=KRT6C PE=1 SV=3" 4.21 2113.2 - 5.39E+06 - - - -0.8796 - 1.933 0.449 - 193 1 2 0 -0.0009 9 0 0 0 6.47E+08 4.46E+05 - - - 4.2638 0.9994 221125_WJC_METTL3_EV_vs_WT_F04.09637.09637.2 0.00416 14-Jul K.QAPTWPSK.- sp|P23490|LORI_HUMAN 1 913.4658 98.1 44402 9637 2 913.464562 457.7402 Loricrin OS=Homo sapiens OX=9606 GN=LORICRIN PE=1 SV=2 8.75 2113.3 - 692200 - - - -1.3192 - 1.552 0.372 - 212.6 1 2 0 -0.0012 8 0 0 0 6.74E+07 6.87E+05 - - - 3.1139 0.9936 221125_WJC_METTL3_EV_vs_WT_F04.09639.09639.2 0.0573 16-Oct K.LEEQDEFEK[136.11].L "sp|Q9NTJ5|SAC1_HUMAN,tr|E9PGZ4|E9PGZ4_HUMAN,tr|A0A5F9ZHN7|A0A5F9ZHN7_HUMAN,tr|C9JV50|C9JV50_HUMAN" 4 1173.5281 1.64 44404 9639 2 1173.522361 587.7713 Phosphatidylinositol-3-phosphatase SAC1 OS=Homo sapiens OX=9606 GN=SACM1L PE=1 SV=2 3.91 2113.5 - 1.02E+06 - - - -4.8895 - 1.735 0.37 - 281.1 1 2 0 -0.0057 9 0 0 0 2.65E+07 1.62E+07 - - - 3.3661 0.9997 221125_WJC_METTL3_EV_vs_WT_F04.09642.09642.2 4.82E-05 18-Nov K.GLNTDELGQK.E sp|Q8N0X7|SPART_HUMAN 1 1073.5353 0.98 44405 9642 2 1073.535176 537.7749 Spartin OS=Homo sapiens OX=9606 GN=SPART PE=1 SV=1 4.37 2113.9 - 1.94E+06 - - - -0.1183 - 2.017 0.335 - 343.8 1 2 0 -0.0001 10 0 0 0 3.98E+07 4.06E+07 - - - 3.4737 0.9999 221125_WJC_METTL3_EV_vs_WT_F04.09644.09644.2 1.33E-05 14/26 K.TPTSSPASSPLVAK.K sp|Q14684|RRP1B_HUMAN 1 1341.714 0.85 44407 9644 2 1341.713616 671.8643 Ribosomal RNA processing protein 1 homolog B OS=Homo sapiens OX=9606 GN=RRP1B PE=1 SV=3 8.41 2114.1 - 426635 - - - -0.2832 - 2.867 0.499 - 704.7 1 2 0 -0.0004 14 0 0 0 1.44E+07 1.69E+07 - - - 5.3696 0.9999 221125_WJC_METTL3_EV_vs_WT_F04.09651.09651.3 0.00102 Nov-36 R.GGDLMAYDRR.G "sp|P61978|HNRPK_HUMAN,tr|Q5T6W2|Q5T6W2_HUMAN" 2 1152.5346 1.18 44412 9651 3 1152.53376 385.1855 Heterogeneous nuclear ribonucleoprotein K OS=Homo sapiens OX=9606 GN=HNRNPK PE=1 SV=1 5.96 2115.1 - 6.05E+06 - - - -0.721 - 2.085 0.389 - 195.5 1 2 0 -0.0008 10 0 0 0 1.44E+08 1.22E+08 - - - 5.0226 0.9999 221125_WJC_METTL3_EV_vs_WT_F04.09655.09655.3 0.00523 Dec-36 K.LVVDSHVQYR.L "sp|Q6P2Q9|PRP8_HUMAN,tr|I3L0J9|I3L0J9_HUMAN" 2 1214.6408 0.92 44416 9655 3 1214.63991 405.8875 Pre-mRNA-processing-splicing factor 8 OS=Homo sapiens OX=9606 GN=PRPF8 PE=1 SV=2 6.74 2115.4 - 478989 - - - -0.7089 - 2.461 0.354 - 202.7 1 2 0 -0.0009 10 0 0 0 1.76E+07 1.91E+07 - - - 5.1166 0.9869 221125_WJC_METTL3_EV_vs_WT_F04.09660.09660.2 0.23 14-May K.DGFTVNTK.V sp|Q8NBP0|TTC13_HUMAN 1 880.429 0.1 44421 9660 2 880.427769 441.2218 Tetratricopeptide repeat protein 13 OS=Homo sapiens OX=9606 GN=TTC13 PE=2 SV=3 5.84 2116.1 - 200851 - - - -1.4516 - 1.083 0.212 - 71.8 2 2 0 -0.0013 8 0 0 0 5.21E+06 5.24E+07 - - - 0.7124 0.9999 221125_WJC_METTL3_EV_vs_WT_F04.09664.09664.3 0.00516 13/36 K.LVVDSHVQYR[166.11].L "sp|Q6P2Q9|PRP8_HUMAN,tr|I3L0J9|I3L0J9_HUMAN" 2 1224.649 0.91 44423 9664 3 1224.648144 409.2236 Pre-mRNA-processing-splicing factor 8 OS=Homo sapiens OX=9606 GN=PRPF8 PE=1 SV=2 6.74 2116.7 - 1.19E+06 - - - -0.7325 - 2.484 0.397 - 310.1 1 2 0 -0.0009 10 0 0 0 1.77E+07 1.95E+07 - - - 5.6231 0.9981 221125_WJC_METTL3_EV_vs_WT_F04.09671.09671.2 0.00562 16-Aug K.DVDEAYMNK.V "sp|P05787|K2C8_HUMAN,tr|F8VUG2|F8VUG2_HUMAN,tr|F8VP67|F8VP67_HUMAN,tr|F8W1U3|F8W1U3_HUMAN" 4 1083.4543 0.52 44428 9671 2 1083.457038 542.7344 "Keratin, type II cytoskeletal 8 OS=Homo sapiens OX=9606 GN=KRT8 PE=1 SV=7" 4.03 2117.6 - 1.01E+06 - - - 2.5502 - 1.438 0.379 - 158.6 1 2 0 0.0028 9 0 0 0 1.26E+07 2.43E+07 - - - 2.8903 0.9996 221125_WJC_METTL3_EV_vs_WT_F04.09672.09672.3 0.0018 Nov-44 R.YPLAAAAER[166.11]PPR[166.11].L sp|Q7Z5L9|I2BP2_HUMAN 1 1330.7261 1.56 44429 9672 3 1330.725312 444.5826 Interferon regulatory factor 2-binding protein 2 OS=Homo sapiens OX=9606 GN=IRF2BP2 PE=1 SV=2 8.75 2117.7 - 610579 - - - -0.5613 - 1.934 0.324 - 148.2 1 2 0 -0.0007 12 0 0 0 7.85E+07 5.03E+07 - - - 3.9804 0.9998 221125_WJC_METTL3_EV_vs_WT_F04.09675.09675.2 1.40E-07 24-Oct R.YIASVQGSTPSPR[166.11].Q "sp|P49792|RBP2_HUMAN,tr|F8WBP7|F8WBP7_HUMAN" 2 1371.7022 0.66 44432 9675 2 1371.700367 686.8584 E3 SUMO-protein ligase RanBP2 OS=Homo sapiens OX=9606 GN=RANBP2 PE=1 SV=2 8.75 2118.1 - 280912 - - - -1.3356 - 2.364 0.418 - 251.2 1 2 0 -0.0018 13 0 0 0 5.18E+06 7.88E+06 - - - 4.3359 0.9995 221125_WJC_METTL3_EV_vs_WT_F04.09678.09678.2 0.000384 16-Jul R.TVIDYNGER.T "sp|P07237|PDIA1_HUMAN,tr|A0A7P0T8C0|A0A7P0T8C0_HUMAN,tr|H7BZ94|H7BZ94_HUMAN,tr|B3KTQ9|B3KTQ9_HUMAN,tr|A0A7P0TA71|A0A7P0TA71_HUMAN,tr|A0A7P0T9K9|A0A7P0T9K9_HUMAN,tr|H0Y3Z3|H0Y3Z3_HUMAN,tr|A0A7P0TA35|A0A7P0TA35_HUMAN,tr|A0A7P0TB26|A0A7P0TB26_HUMAN,tr|I3L0S0|I3L0S0_HUMAN,tr|I3L3P5|I3L3P5_HUMAN,tr|A0A7P0T8J3|A0A7P0T8J3_HUMAN" 12 1065.5091 1.38 44433 9678 2 1065.509027 533.7618 Protein disulfide-isomerase OS=Homo sapiens OX=9606 GN=P4HB PE=1 SV=3 4.37 2118.4 - 1.16E+06 - - - -0.0572 - 1.475 0.38 - 131.3 1 2 0 -0.0001 9 0 0 0 2.94E+08 2.13E+08 - - - 2.9721 0.9776 221125_WJC_METTL3_EV_vs_WT_F04.09679.09679.2 0.343 16-Jun K.AESQLLEC[160.03]K[136.11].A sp|P12270|TPR_HUMAN 1 1084.5314 3.77 44434 9679 2 1084.529787 543.273 Nucleoprotein TPR OS=Homo sapiens OX=9606 GN=TPR PE=1 SV=3 4.53 2118.5 - 860664 - - - -1.4965 - 1.28 0.083 - 78.4 1 2 0 -0.0016 9 0 0 0 5.93E+07 1.57E+07 - - - 0.3677 0.9997 221125_WJC_METTL3_EV_vs_WT_F04.09681.09681.2 5.15E-06 24-Oct R.YIASVQGSTPSPR.Q "sp|P49792|RBP2_HUMAN,tr|F8WBP7|F8WBP7_HUMAN" 2 1361.6939 0.66 44436 9681 2 1361.697154 681.8542 E3 SUMO-protein ligase RanBP2 OS=Homo sapiens OX=9606 GN=RANBP2 PE=1 SV=2 8.75 2118.8 - 239793 - - - 2.3684 - 2.18 0.529 - 275.5 1 2 0 0.0032 13 0 0 0 5.18E+06 7.88E+06 - - - 4.9473 0.9896 221125_WJC_METTL3_EV_vs_WT_F04.09684.09684.2 6.63E-06 18-Oct R.TSSSLTPIGH.S "sp|Q14671|PUM1_HUMAN,tr|Q5T1Z8|Q5T1Z8_HUMAN,tr|H0YDK8|H0YDK8_HUMAN,tr|H0YCK1|H0YCK1_HUMAN,tr|Q5T1Z4|Q5T1Z4_HUMAN,tr|E9PR38|E9PR38_HUMAN" 6 998.5033 - 44438 9684 2 998.503903 500.2589 Pumilio homolog 1 OS=Homo sapiens OX=9606 GN=PUM1 PE=1 SV=3 6.4 2119.1 - 6.17E+06 - - - 0.6289 - 2.171 0.44 - 481.5 1 1 0 0.0006 10 0 0 0 - - - - - 4.4544 0.9993 221125_WJC_METTL3_EV_vs_WT_F04.09686.09686.2 0.0617 16-Jul K.DDLSGADIK.A sp|P62191|PRS4_HUMAN 1 932.4451 0.6 44439 9686 2 932.445157 467.2298 26S proteasome regulatory subunit 4 OS=Homo sapiens OX=9606 GN=PSMC1 PE=1 SV=1 3.93 2119.4 - 1.80E+06 - - - 0.0708 - 1.498 0.335 - 137.2 1 2 0 0.0001 9 0 0 0 4.09E+07 6.77E+07 - - - 2.6845 0.9993 221125_WJC_METTL3_EV_vs_WT_F04.09692.09692.2 2.77E-05 16-Sep R.TESPGIPVR[166.11].L sp|Q5T0B9|ZN362_HUMAN 1 964.5217 1.76 44445 9692 2 964.519902 483.2681 Zinc finger protein 362 OS=Homo sapiens OX=9606 GN=ZNF362 PE=1 SV=1 5.66 2120 - 241211 - - - -1.8797 - 1.808 0.358 - 423.6 1 2 0 -0.0018 9 0 0 0 5.40E+06 3.07E+06 - - - 3.3979 0.9999 221125_WJC_METTL3_EV_vs_WT_F04.09697.09697.3 5.32E-06 Nov-32 R.C[160.03]YLLVHQAK[136.11].R sp|Q08J23|NSUN2_HUMAN 1 1138.6048 0.001 44448 9697 3 1138.603502 380.5422 RNA cytosine C(5)-methyltransferase NSUN2 OS=Homo sapiens OX=9606 GN=NSUN2 PE=1 SV=2 8.21 2120.6 - 527862 - - - -1.1839 - 2.005 0.455 - 123 1 2 0 -0.0013 9 0 0 0 0.00E+00 2.89E+07 - - - 5.709 0.9946 221125_WJC_METTL3_EV_vs_WT_F04.09698.09698.2 0.179 16-Sep R.RLVGDVIQR.F "sp|O00746|NDKM_HUMAN,tr|Q4TT34|Q4TT34_HUMAN,tr|A0A087WVT9|A0A087WVT9_HUMAN,tr|H0Y6J0|H0Y6J0_HUMAN,tr|F2Z2X0|F2Z2X0_HUMAN" 5 1054.6247 1.85 44449 9698 2 1054.625994 528.3196 "Nucleoside diphosphate kinase, mitochondrial OS=Homo sapiens OX=9606 GN=NME4 PE=1 SV=1" 9.6 2120.7 - 1.02E+06 - - - 1.2014 - 1.667 0.109 - 156.5 1 2 0 0.0013 9 0 0 0 8.48E+08 4.57E+08 - - - 1.3241 0.9997 221125_WJC_METTL3_EV_vs_WT_F04.09702.09702.3 4.74E-05 14/48 K.LLIGADGHNSGVR[166.11].Q "sp|Q9Y2Z9|COQ6_HUMAN,tr|G3V3A1|G3V3A1_HUMAN,tr|A0A0D9SFJ1|A0A0D9SFJ1_HUMAN" 3 1317.7029 13.89 44453 9702 3 1317.697641 440.2416 "Ubiquinone biosynthesis monooxygenase COQ6, mitochondrial OS=Homo sapiens OX=9606 GN=COQ6 PE=1 SV=2" 6.74 2121.3 - 342249 - - - -3.9668 - 2.574 0.473 - 240.1 1 2 0 -0.0052 13 0 0 0 7.72E+07 5.56E+06 - - - 6.3755 0.9994 221125_WJC_METTL3_EV_vs_WT_F04.09703.09703.2 0.527 16-Sep K.NSALSAQLR[166.11].E "sp|P47897|SYQ_HUMAN,tr|F2Z2V6|F2Z2V6_HUMAN,tr|A0A0U1RQC3|A0A0U1RQC3_HUMAN,tr|C9J165|C9J165_HUMAN,tr|A0A0U1RQT0|A0A0U1RQT0_HUMAN,tr|A0A0U1RQE9|A0A0U1RQE9_HUMAN,tr|A0A0U1RQM8|A0A0U1RQM8_HUMAN,tr|A0A0U1RQU2|A0A0U1RQU2_HUMAN" 8 968.5279 0.85 44454 9703 2 968.527174 485.2712 Glutamine--tRNA ligase OS=Homo sapiens OX=9606 GN=QARS1 PE=1 SV=1 9.75 2121.4 - 333095 - - - -0.7114 - 1.935 0.256 - 405.4 1 2 0 -0.0007 9 0 0 0 7.14E+07 8.37E+07 - - - 2.8413 0.9988 221125_WJC_METTL3_EV_vs_WT_F04.09704.09704.2 0.000364 18-Sep K.AAVAWANQNR.A sp|Q96F86|EDC3_HUMAN 1 1099.5523 0.23 44455 9704 2 1099.549755 550.7834 Enhancer of mRNA-decapping protein 3 OS=Homo sapiens OX=9606 GN=EDC3 PE=1 SV=1 9.79 2121.5 - 340452 - - - -2.3055 - 2.087 0.272 - 303.1 1 2 0 -0.0025 10 0 0 0 2.97E+07 1.31E+08 - - - 3.1028 0.9991 221125_WJC_METTL3_EV_vs_WT_F04.09709.09709.2 0.13 16-Sep R.TVIDYNGER[166.11].T "sp|P07237|PDIA1_HUMAN,tr|A0A7P0T8C0|A0A7P0T8C0_HUMAN,tr|H7BZ94|H7BZ94_HUMAN,tr|B3KTQ9|B3KTQ9_HUMAN,tr|A0A7P0TA71|A0A7P0TA71_HUMAN,tr|A0A7P0T9K9|A0A7P0T9K9_HUMAN,tr|H0Y3Z3|H0Y3Z3_HUMAN,tr|A0A7P0TA35|A0A7P0TA35_HUMAN,tr|A0A7P0TB26|A0A7P0TB26_HUMAN,tr|I3L0S0|I3L0S0_HUMAN,tr|I3L3P5|I3L3P5_HUMAN,tr|A0A7P0T8J3|A0A7P0T8J3_HUMAN" 12 1075.5174 1.37 44459 9709 2 1075.516001 538.766 Protein disulfide-isomerase OS=Homo sapiens OX=9606 GN=P4HB PE=1 SV=3 4.37 2121.9 - 7.26E+06 - - - -1.2617 - 1.669 0.303 - 240.7 1 2 0 -0.0014 9 0 0 0 2.94E+08 2.15E+08 - - - 2.7604 0.9977 221125_WJC_METTL3_EV_vs_WT_F04.09711.09711.3 0.000395 13/36 R.IR[166.11]ELTAVVQK[136.11].R "sp|P23396|RS3_HUMAN,tr|E9PL09|E9PL09_HUMAN,tr|E9PK82|E9PK82_HUMAN,tr|F2Z2S8|F2Z2S8_HUMAN,tr|H0YCJ7|H0YCJ7_HUMAN,tr|E9PQ96|E9PQ96_HUMAN,tr|E9PJH4|E9PJH4_HUMAN,tr|E9PPU1|E9PPU1_HUMAN,tr|H0YF32|H0YF32_HUMAN" 9 1173.72 0.66 44461 9711 3 1173.717461 392.2473 40S ribosomal protein S3 OS=Homo sapiens OX=9606 GN=RPS3 PE=1 SV=2 8.75 2122.1 - 1.19E+06 - - - -2.1871 - 2.435 0.291 - 284.7 1 2 1 -0.0026 10 0 0 0 7.05E+07 1.06E+08 - - - 4.3827 0.9996 221125_WJC_METTL3_EV_vs_WT_F04.09714.09714.2 5.97E-05 18-Nov K.YLESEEYQER[166.11].Y "sp|Q9Y676|RT18B_HUMAN,tr|A0A0G2JIC6|A0A0G2JIC6_HUMAN" 2 1354.5916 1.08 44464 9714 2 1354.588363 678.3031 "28S ribosomal protein S18b, mitochondrial OS=Homo sapiens OX=9606 GN=MRPS18B PE=1 SV=1" 4.09 2122.5 - 719663 - - - -2.4229 - 2.246 0.431 - 440.5 1 2 0 -0.0033 10 0 0 0 3.49E+07 3.25E+07 - - - 4.4819 0.9985 221125_WJC_METTL3_EV_vs_WT_F04.09719.09719.2 0.000165 18-Oct K.YLESEEYQER.Y "sp|Q9Y676|RT18B_HUMAN,tr|A0A0G2JIC6|A0A0G2JIC6_HUMAN" 2 1344.5834 1.08 44467 9719 2 1344.580827 673.299 "28S ribosomal protein S18b, mitochondrial OS=Homo sapiens OX=9606 GN=MRPS18B PE=1 SV=1" 4.09 2123 - 1.23E+06 - - - -1.895 - 1.562 0.321 - 317.4 1 2 0 -0.0025 10 0 0 0 3.49E+07 3.24E+07 - - - 2.6559 0.9991 221125_WJC_METTL3_EV_vs_WT_F04.09720.09720.2 0.00305 20-Aug R.QDVYGPQPQVR[166.11].V "sp|O60716|CTND1_HUMAN,tr|A0A669KB62|A0A669KB62_HUMAN,tr|A0A669KB05|A0A669KB05_HUMAN,tr|C9JZR2|C9JZR2_HUMAN,tr|H0YC95|H0YC95_HUMAN" 5 1295.6498 1.19 44468 9720 2 1295.652205 648.8322 Catenin delta-1 OS=Homo sapiens OX=9606 GN=CTNND1 PE=1 SV=1 5.84 2123.2 - 331873 - - - 1.8801 - 1.786 0.35 - 167.4 1 2 0 0.0024 11 0 0 0 2.03E+07 1.70E+07 - - - 3.1943 0.9993 221125_WJC_METTL3_EV_vs_WT_F04.09721.09721.2 0.256 16-Oct K.NSALSAQLR.E "sp|P47897|SYQ_HUMAN,tr|F2Z2V6|F2Z2V6_HUMAN,tr|A0A0U1RQC3|A0A0U1RQC3_HUMAN,tr|C9J165|C9J165_HUMAN,tr|A0A0U1RQT0|A0A0U1RQT0_HUMAN,tr|A0A0U1RQE9|A0A0U1RQE9_HUMAN,tr|A0A0U1RQM8|A0A0U1RQM8_HUMAN,tr|A0A0U1RQU2|A0A0U1RQU2_HUMAN" 8 958.5196 0.82 44469 9721 2 958.51846 480.2671 Glutamine--tRNA ligase OS=Homo sapiens OX=9606 GN=QARS1 PE=1 SV=1 9.75 2123.3 - 1.31E+06 - - - -1.182 - 2.055 0.257 - 585 1 2 0 -0.0011 9 0 0 0 6.81E+07 8.28E+07 - - - 3.0226 0.9405 221125_WJC_METTL3_EV_vs_WT_F04.09723.09723.2 0.997 12-Jun R.INIPPQR[166.11].G "sp|Q13283|G3BP1_HUMAN,tr|A0A7I2V5M7|A0A7I2V5M7_HUMAN,tr|A0A7P0P2U7|A0A7P0P2U7_HUMAN,tr|A0A7I2YQU8|A0A7I2YQU8_HUMAN,tr|A0A7I2V548|A0A7I2V548_HUMAN,tr|A0A7I2V565|A0A7I2V565_HUMAN,tr|A0A7I2YQN9|A0A7I2YQN9_HUMAN" 7 846.4951 1.17 44471 9723 2 846.492906 424.2548 Ras GTPase-activating protein-binding protein 1 OS=Homo sapiens OX=9606 GN=G3BP1 PE=1 SV=1 9.75 2123.6 - 589836 - - - -2.6001 - 1.444 0 - 145.1 1 2 0 -0.0022 7 0 0 0 1.53E+07 1.30E+07 - - - 0.2045 0.9998 221125_WJC_METTL3_EV_vs_WT_F04.09728.09728.2 0.000575 20-Oct K.FVTSNTQELGK.D "sp|Q9BXP5|SRRT_HUMAN,tr|H7C3A1|H7C3A1_HUMAN" 2 1222.6194 1.27 44474 9728 2 1222.620031 612.317 Serrate RNA effector molecule homolog OS=Homo sapiens OX=9606 GN=SRRT PE=1 SV=1 6 2124.2 - 4.70E+06 - - - 0.5431 - 2.001 0.483 - 249.4 1 2 0 0.0007 11 0 0 0 8.28E+07 6.50E+07 - - - 4.4847 0.9964 221125_WJC_METTL3_EV_vs_WT_F04.09729.09729.2 0.00877 14-Jul K.YQAEIPDR[166.11].L sp|O94776|MTA2_HUMAN 1 1000.4853 2.25 44475 9729 2 1000.4819 501.2499 Metastasis-associated protein MTA2 OS=Homo sapiens OX=9606 GN=MTA2 PE=1 SV=1 4.37 2124.3 - 1.56E+06 - - - -3.4283 - 1.594 0.325 - 165.5 1 2 0 -0.0034 8 0 0 0 1.95E+08 8.69E+07 - - - 2.8466 0.998 221125_WJC_METTL3_EV_vs_WT_F04.09730.09730.3 0.0334 16/36 R.IRELTAVVQK.R "sp|P23396|RS3_HUMAN,tr|E9PL09|E9PL09_HUMAN,tr|E9PK82|E9PK82_HUMAN,tr|F2Z2S8|F2Z2S8_HUMAN,tr|H0YCJ7|H0YCJ7_HUMAN,tr|E9PQ96|E9PQ96_HUMAN,tr|E9PJH4|E9PJH4_HUMAN,tr|E9PPU1|E9PPU1_HUMAN,tr|H0YF32|H0YF32_HUMAN" 9 1155.6976 0.66 44476 9730 3 1155.695418 386.2398 40S ribosomal protein S3 OS=Homo sapiens OX=9606 GN=RPS3 PE=1 SV=2 8.75 2124.4 - 1.68E+06 - - - -1.8517 - 2.649 0.265 - 278.7 1 2 1 -0.0021 10 0 0 0 7.05E+07 1.06E+08 - - - 4.3389 0.9998 221125_WJC_METTL3_EV_vs_WT_F04.09731.09731.2 0.00434 16-Nov R.AEDAVEAIR[166.11].G "sp|Q9BWF3|RBM4_HUMAN,sp|Q9BQ04|RBM4B_HUMAN,tr|E9PM61|E9PM61_HUMAN,tr|D6R9K7|D6R9K7_HUMAN,tr|J3QRR5|J3QRR5_HUMAN,tr|E9PB51|E9PB51_HUMAN,tr|U3KQD5|U3KQD5_HUMAN,tr|E9PLB0|E9PLB0_HUMAN" 8 982.4959 1.5 44477 9731 2 982.495382 492.2552 RNA-binding protein 4 OS=Homo sapiens OX=9606 GN=RBM4 PE=1 SV=1 4.14 2124.5 - 1.15E+06 - - - -0.5211 - 2.219 0.382 - 637.7 1 2 0 -0.0005 9 0 0 0 8.53E+07 5.70E+07 - - - 4.1682 0.9945 221125_WJC_METTL3_EV_vs_WT_F04.09734.09734.2 0.000152 20-Dec M.LGQAEEVVQER[166.11].L "sp|P17987|TCPA_HUMAN,tr|F5GZ03|F5GZ03_HUMAN,tr|F5H282|F5H282_HUMAN,tr|E7EQR6|E7EQR6_HUMAN,tr|E7ERF2|E7ERF2_HUMAN" 5 1266.6444 0.31 44478 9734 2 1266.644686 634.3295 T-complex protein 1 subunit alpha OS=Homo sapiens OX=9606 GN=TCP1 PE=1 SV=1 4.25 2124.9 - 427659 - - - 0.2653 - 2.726 0.506 - 800.4 1 1 0 0.0003 11 0 0 0 4.74E+06 1.55E+07 - - - 5.4911 0.9925 221125_WJC_METTL3_EV_vs_WT_F04.09736.09736.2 0.384 16-Oct R.R[166.11]LVGDVIQR[166.11].F "sp|O00746|NDKM_HUMAN,tr|Q4TT34|Q4TT34_HUMAN,tr|A0A087WVT9|A0A087WVT9_HUMAN,tr|H0Y6J0|H0Y6J0_HUMAN,tr|F2Z2X0|F2Z2X0_HUMAN" 5 1074.6413 1.85 44479 9736 2 1074.640336 538.3279 "Nucleoside diphosphate kinase, mitochondrial OS=Homo sapiens OX=9606 GN=NME4 PE=1 SV=1" 9.6 2125.1 - 1.06E+07 - - - -0.8663 - 1.242 0.167 - 208.8 1 2 0 -0.0009 9 0 0 0 8.48E+08 4.57E+08 - - - 0.9012 0.9849 221125_WJC_METTL3_EV_vs_WT_F04.09737.09737.2 0.111 18-Dec R.IR[166.11]ELTAVVQK[136.11].R "sp|P23396|RS3_HUMAN,tr|E9PL09|E9PL09_HUMAN,tr|E9PK82|E9PK82_HUMAN,tr|F2Z2S8|F2Z2S8_HUMAN,tr|H0YCJ7|H0YCJ7_HUMAN,tr|E9PQ96|E9PQ96_HUMAN,tr|E9PJH4|E9PJH4_HUMAN,tr|E9PPU1|E9PPU1_HUMAN,tr|H0YF32|H0YF32_HUMAN" 9 1173.72 0.65 44480 9737 2 1173.718537 587.8673 40S ribosomal protein S3 OS=Homo sapiens OX=9606 GN=RPS3 PE=1 SV=2 8.75 2125.2 - 1.36E+06 - - - -1.2703 - 2.024 0.184 - 619 1 2 1 -0.0015 10 0 0 0 2.42E+07 3.70E+07 - - - 2.3676 0.9992 221125_WJC_METTL3_EV_vs_WT_F04.09738.09738.2 0.00325 18-Aug K.QAGPASVPLR[166.11].T sp|P30101|PDIA3_HUMAN 1 1004.5642 2.34 44481 9738 2 1004.564575 503.2894 Protein disulfide-isomerase A3 OS=Homo sapiens OX=9606 GN=PDIA3 PE=1 SV=4 9.75 2125.4 - 393903 - - - 0.3245 - 1.765 0.274 - 243.9 1 2 0 0.0003 10 0 0 0 1.35E+07 5.78E+06 - - - 2.6505 0.9998 221125_WJC_METTL3_EV_vs_WT_F04.09741.09741.2 0.054 18-Dec K.AAVAWANQNR[166.11].A sp|Q96F86|EDC3_HUMAN 1 1109.5606 1.67 44482 9741 2 1109.559549 555.7876 Enhancer of mRNA-decapping protein 3 OS=Homo sapiens OX=9606 GN=EDC3 PE=1 SV=1 9.79 2125.7 - 1.01E+06 - - - -0.9112 - 2.654 0.341 - 863.8 1 2 0 -0.001 10 0 0 0 3.40E+07 2.04E+07 - - - 4.2838 0.9991 221125_WJC_METTL3_EV_vs_WT_F04.09747.09747.2 0.0316 14-Sep R.HLEAILTK[136.11].L "sp|Q9H583|HEAT1_HUMAN,tr|Q5T3Q7|Q5T3Q7_HUMAN" 2 931.5582 0.97 44486 9747 2 931.557367 466.7864 HEAT repeat-containing protein 1 OS=Homo sapiens OX=9606 GN=HEATR1 PE=1 SV=3 6.75 2126.5 - 467122 - - - -0.9124 - 1.522 0.312 - 189.8 1 2 0 -0.0008 8 0 0 0 1.20E+07 1.24E+07 - - - 2.6119 0.9875 221125_WJC_METTL3_EV_vs_WT_F04.09751.09751.3 0.0155 14/36 K.TPLRPLDPTR.L "sp|Q04637|IF4G1_HUMAN,tr|C9J2Z7|C9J2Z7_HUMAN,tr|E7EUU4|E7EUU4_HUMAN,tr|E9PGM1|E9PGM1_HUMAN,tr|C9J6B6|C9J6B6_HUMAN,tr|E7EX73|E7EX73_HUMAN,tr|C9K073|C9K073_HUMAN,tr|A0A7I2Y1C3|A0A7I2Y1C3_HUMAN,tr|C9JF13|C9JF13_HUMAN,tr|A0A6Q8PFB2|A0A6Q8PFB2_HUMAN" 10 1164.6615 0.87 44488 9751 3 1164.658602 389.2278 Eukaryotic translation initiation factor 4 gamma 1 OS=Homo sapiens OX=9606 GN=EIF4G1 PE=1 SV=4 9.26 2127 - 2.55E+06 - - - -2.4943 - 1.912 0.163 - 310.2 1 2 0 -0.0029 10 0 0 0 6.37E+07 7.36E+07 - - - 2.2494 0.9673 221125_WJC_METTL3_EV_vs_WT_F04.09752.09752.2 0.00488 12-Oct N.HFVEEFK[136.11].R "sp|P0DMV8|HS71A_HUMAN,sp|P34931|HS71L_HUMAN,sp|P0DMV9|HS71B_HUMAN,tr|Q53FA3|Q53FA3_HUMAN,tr|V9GZ37|V9GZ37_HUMAN,tr|A0A0G2JIW1|A0A0G2JIW1_HUMAN" 6 942.4691 0.27 44489 9752 2 942.466727 472.2418 Heat shock 70 kDa protein 1A OS=Homo sapiens OX=9606 GN=HSPA1A PE=1 SV=1 5.4 2127.2 - 1.12E+06 - - - -2.4839 - 1.98 0.405 - 390.9 1 1 0 -0.0023 7 0 0 0 1.01E+07 3.77E+07 - - - 4.196 0.9998 221125_WJC_METTL3_EV_vs_WT_F04.09755.09755.2 1.82E-05 20-Dec R.QDVYGPQPQVR.V "sp|O60716|CTND1_HUMAN,tr|A0A669KB62|A0A669KB62_HUMAN,tr|A0A669KB05|A0A669KB05_HUMAN,tr|C9JZR2|C9JZR2_HUMAN,tr|H0YC95|H0YC95_HUMAN" 5 1285.6415 1.19 44490 9755 2 1285.639653 643.828 Catenin delta-1 OS=Homo sapiens OX=9606 GN=CTNND1 PE=1 SV=1 5.84 2127.6 - 1.03E+06 - - - -1.4359 - 2.053 0.469 - 472.3 1 2 0 -0.0018 11 0 0 0 2.03E+07 1.70E+07 - - - 4.4503 0.9998 221125_WJC_METTL3_EV_vs_WT_F04.09757.09757.2 0.00036 24-Oct R.SLDGAAAVDSADR.S "sp|P11171|EPB41_HUMAN,tr|A0A2R8YFR9|A0A2R8YFR9_HUMAN,tr|A0A2R8Y420|A0A2R8Y420_HUMAN,tr|A0A2R8YCW8|A0A2R8YCW8_HUMAN,tr|A0A2R8Y7N0|A0A2R8Y7N0_HUMAN,tr|A0A3B3ITP0|A0A3B3ITP0_HUMAN,tr|A0A3B3IU06|A0A3B3IU06_HUMAN,tr|A0A2R8Y5G2|A0A2R8Y5G2_HUMAN,tr|A0A2U3TZH6|A0A2U3TZH6_HUMAN,tr|A0A3B3IUD6|A0A3B3IUD6_HUMAN,tr|A0A2R8Y7Y3|A0A2R8Y7Y3_HUMAN,tr|A0A2R8Y570|A0A2R8Y570_HUMAN,tr|A0A2R8Y6G5|A0A2R8Y6G5_HUMAN,tr|A0A2R8Y5Z6|A0A2R8Y5Z6_HUMAN,tr|A0A2R8YD30|A0A2R8YD30_HUMAN,tr|A0A2R8Y4N6|A0A2R8Y4N6_HUMAN" 16 1246.579 0.59 44492 9757 2 1246.577377 624.2968 Protein 4.1 OS=Homo sapiens OX=9606 GN=EPB41 PE=1 SV=4 3.93 2127.8 - 1.01E+06 - - - -1.2691 - 2.27 0.46 - 256.4 1 2 0 -0.0016 13 0 0 0 1.95E+07 3.32E+07 - - - 4.5421 0.9998 221125_WJC_METTL3_EV_vs_WT_F04.09758.09758.2 6.30E-05 26-Oct R.LDAEPRPPPTQEAA.- "sp|Q9Y285|SYFA_HUMAN,tr|K7ER00|K7ER00_HUMAN" 2 1490.7365 2.01 44493 9758 2 1490.733607 746.3755 Phenylalanine--tRNA ligase alpha subunit OS=Homo sapiens OX=9606 GN=FARSA PE=1 SV=3 4.14 2127.9 - 348617 - - - -1.9554 - 2.369 0.572 - 312.7 1 2 0 -0.0029 14 0 0 0 4.97E+07 2.48E+07 - - - 5.4292 0.9998 221125_WJC_METTL3_EV_vs_WT_F04.09762.09762.2 4.36E-05 18-Sep K.TAGNSEFLGK.T "sp|P78344|IF4G2_HUMAN,tr|H0YD99|H0YD99_HUMAN,tr|H0YCF8|H0YCF8_HUMAN,tr|H0YEC5|H0YEC5_HUMAN,tr|H0YDC0|H0YDC0_HUMAN,tr|H0YEN8|H0YEN8_HUMAN,tr|H0Y3P2|H0Y3P2_HUMAN,tr|H0YCH5|H0YCH5_HUMAN,tr|H0YD77|H0YD77_HUMAN,tr|D3DQV9|D3DQV9_HUMAN" 10 1022.5033 1.37 44496 9762 2 1022.502661 512.2589 Eukaryotic translation initiation factor 4 gamma 2 OS=Homo sapiens OX=9606 GN=EIF4G2 PE=1 SV=1 5.66 2128.4 - 2.65E+06 - - - -0.6005 - 1.832 0.452 - 207.2 1 2 0 -0.0006 10 0 0 0 4.13E+08 3.02E+08 - - - 4.0692 0.8529 221125_WJC_METTL3_EV_vs_WT_F04.09765.09765.2 0.291 18-Jul R.AEAEQQQQER.A sp|Q13515|BFSP2_HUMAN 1 1215.548 55.7 44498 9765 2 1215.541716 608.7813 Phakinin OS=Homo sapiens OX=9606 GN=BFSP2 PE=1 SV=1 4.25 2128.7 - 756877 - - - -5.1639 - 1.359 0.12 - 158.4 1 2 0 -0.0063 10 0 0 0 7.21E+07 1.29E+06 - - - 0.7816 0.9966 221125_WJC_METTL3_EV_vs_WT_F04.09770.09770.2 0.633 12-Jun R.INIPPQR.G "sp|Q13283|G3BP1_HUMAN,tr|A0A7I2V5M7|A0A7I2V5M7_HUMAN,tr|A0A7P0P2U7|A0A7P0P2U7_HUMAN,tr|A0A7I2YQU8|A0A7I2YQU8_HUMAN,tr|A0A7I2V548|A0A7I2V548_HUMAN,tr|A0A7I2V565|A0A7I2V565_HUMAN,tr|A0A7I2YQN9|A0A7I2YQN9_HUMAN" 7 836.4868 1.16 44502 9770 2 836.486087 419.2507 Ras GTPase-activating protein-binding protein 1 OS=Homo sapiens OX=9606 GN=G3BP1 PE=1 SV=1 9.75 2129.2 - 488552 - - - -0.8966 - 1.449 0.171 - 157.9 1 2 0 -0.0008 7 0 0 0 1.58E+07 1.37E+07 - - - 1.4789 0.9964 221125_WJC_METTL3_EV_vs_WT_F04.09772.09772.2 0.051 14-Aug R.ELNITAAK.E "sp|P62081|RS7_HUMAN,tr|B5MCP9|B5MCP9_HUMAN,tr|A0A2R8Y623|A0A2R8Y623_HUMAN" 3 858.4811 0.9 44503 9772 2 858.481031 430.2478 40S ribosomal protein S7 OS=Homo sapiens OX=9606 GN=RPS7 PE=1 SV=1 6.1 2129.5 - 1.15E+06 - - - -0.0606 - 1.385 0.177 - 295.1 1 2 0 -0.0001 8 0 0 0 2.47E+07 2.76E+07 - - - 1.3306 0.994 221125_WJC_METTL3_EV_vs_WT_F04.09773.09773.3 0.0141 Oct-32 R.FK[136.11]EEAEMLK[136.11].G "sp|Q9BYP7|WNK3_HUMAN,sp|Q9H4A3|WNK1_HUMAN,sp|Q9Y3S1|WNK2_HUMAN,tr|F5GWT4|F5GWT4_HUMAN,tr|A0A087WYK2|A0A087WYK2_HUMAN,tr|A6PVV2|A6PVV2_HUMAN,tr|F8W9F9|F8W9F9_HUMAN,tr|H0Y7T5|H0Y7T5_HUMAN,tr|F6UYG0|F6UYG0_HUMAN" 9 1139.5867 0.001 44504 9773 3 1139.582179 380.8695 Serine\threonine-protein kinase WNK3 OS=Homo sapiens OX=9606 GN=WNK3 PE=1 SV=3 4.79 2129.6 - 855562 - - - -4.0085 - 1.849 0.388 - 125.5 1 2 1 -0.0046 9 0 0 0 0.00E+00 1.58E+07 - - - 4.717 0.9999 221125_WJC_METTL3_EV_vs_WT_F04.09776.09776.2 0.000154 20-Nov K.SEVATLTAAGK.E sp|P36542|ATPG_HUMAN 1 1046.5608 0.9 44505 9776 2 1046.561317 524.2877 "ATP synthase subunit gamma, mitochondrial OS=Homo sapiens OX=9606 GN=ATP5F1C PE=1 SV=1" 5.72 2129.9 - 9.00E+06 - - - 0.5045 - 2.208 0.482 - 434.2 1 2 0 0.0005 11 0 0 0 2.76E+08 3.07E+08 - - - 4.7437 0.9997 221125_WJC_METTL3_EV_vs_WT_F04.09778.09778.2 0.000359 18-Aug K.GTAVVNGEFK.D sp|P30048|PRDX3_HUMAN 1 1020.524 0.65 44507 9778 2 1020.52498 511.2693 "Thioredoxin-dependent peroxide reductase, mitochondrial OS=Homo sapiens OX=9606 GN=PRDX3 PE=1 SV=3" 6 2130.1 - 1.10E+06 - - - 0.9505 - 1.801 0.427 - 265.6 1 2 0 0.001 10 0 0 0 2.19E+07 3.35E+07 - - - 3.8368 0.9996 221125_WJC_METTL3_EV_vs_WT_F04.09781.09781.2 0.000215 26-Jun R.LDAEPR[166.11]PPPTQEAA.- "sp|Q9Y285|SYFA_HUMAN,tr|K7ER00|K7ER00_HUMAN" 2 1500.7448 1.99 44510 9781 2 1500.742129 751.3797 Phenylalanine--tRNA ligase alpha subunit OS=Homo sapiens OX=9606 GN=FARSA PE=1 SV=3 4.14 2130.4 - 277253 - - - -1.7745 - 1.63 0.492 - 110.7 1 2 0 -0.0027 14 0 0 0 4.91E+07 2.47E+07 - - - 3.9001 0.9997 221125_WJC_METTL3_EV_vs_WT_F04.09786.09786.2 0.0235 18-Aug K.TALIHDGLAR.G sp|P25398|RS12_HUMAN 1 1065.5931 1.88 44513 9786 2 1065.593442 533.8038 40S ribosomal protein S12 OS=Homo sapiens OX=9606 GN=RPS12 PE=1 SV=3 6.41 2131.1 - 5.12E+06 - - - 0.3275 - 1.855 0.405 - 268.3 1 2 0 0.0003 10 0 0 0 1.23E+09 6.54E+08 - - - 3.7569 0.9299 221125_WJC_METTL3_EV_vs_WT_F04.09787.09787.2 0.393 16-Aug T.ALIHDGLAR.G sp|P25398|RS12_HUMAN 1 964.5454 1.85 44514 9787 2 964.545571 483.28 40S ribosomal protein S12 OS=Homo sapiens OX=9606 GN=RPS12 PE=1 SV=3 6.79 2131.2 - 1.78E+06 - - - 0.1628 - 1.52 0.262 - 243.3 1 1 0 0.0002 9 0 0 0 4.53E+08 2.44E+08 - - - 2.1874 0.97 221125_WJC_METTL3_EV_vs_WT_F04.09788.09788.2 0.012 18-Sep H.SGYSDSAVLK.L "sp|P43243|MATR3_HUMAN,tr|B3KM87|B3KM87_HUMAN,tr|A8MXP9|A8MXP9_HUMAN,tr|D6RBK5|D6RBK5_HUMAN,tr|A0A0R4J2E8|A0A0R4J2E8_HUMAN,tr|H0Y8T4|H0Y8T4_HUMAN,tr|D6REM6|D6REM6_HUMAN" 7 1025.5029 0.25 44515 9788 2 1025.504536 513.7587 Matrin-3 OS=Homo sapiens OX=9606 GN=MATR3 PE=1 SV=2 5.55 2131.3 - 1.92E+06 - - - 1.5563 - 1.658 0.428 - 161.9 1 1 0 0.0016 10 0 0 0 3.90E+08 1.57E+09 - - - 3.613 0.9999 221125_WJC_METTL3_EV_vs_WT_F04.09790.09790.2 2.11E-06 18-Oct R.GC[160.03]VNFEGADR.L sp|Q8IU81|I2BP1_HUMAN 1 1123.4717 1.66 44517 9790 2 1123.47182 562.7431 Interferon regulatory factor 2-binding protein 1 OS=Homo sapiens OX=9606 GN=IRF2BP1 PE=1 SV=1 4.37 2131.4 - 1.21E+06 - - - 0.1451 - 2.039 0.563 - 473 1 2 0 0.0002 10 0 0 0 4.57E+07 2.74E+07 - - - 5.188 0.9958 221125_WJC_METTL3_EV_vs_WT_F04.09791.09791.2 0.000208 18-Nov R.C[160.03]YLVTGEGQK.A "sp|Q12769|NU160_HUMAN,tr|E9PR16|E9PR16_HUMAN,tr|G3V198|G3V198_HUMAN" 3 1153.5438 1.23 44518 9791 2 1153.545775 577.7792 Nuclear pore complex protein Nup160 OS=Homo sapiens OX=9606 GN=NUP160 PE=1 SV=3 5.99 2131.5 - 839173 - - - 1.7477 - 1.828 0.139 - 392.7 1 2 0 0.002 10 0 0 0 2.61E+07 2.12E+07 - - - 1.7508 0.9981 221125_WJC_METTL3_EV_vs_WT_F04.09792.09792.2 0.000198 26-Nov R.LGGGLGVAGGNSTR[166.11].E sp|Q9NPJ6|MED4_HUMAN 1 1224.645 1.59 44519 9792 2 1224.650269 613.3298 Mediator of RNA polymerase II transcription subunit 4 OS=Homo sapiens OX=9606 GN=MED4 PE=1 SV=1 9.75 2131.7 - 442783 - - - 4.2878 - 2.305 0.439 - 389.9 1 2 0 0.0053 14 0 0 0 1.19E+07 7.50E+06 - - - 4.3774 0.9959 221125_WJC_METTL3_EV_vs_WT_F04.09797.09797.2 0.00745 18-Aug R.TSLGPNGLDK[136.11].M "sp|P48643|TCPE_HUMAN,tr|E9PCA1|E9PCA1_HUMAN,tr|B7ZAR1|B7ZAR1_HUMAN" 3 1008.5331 0.67 44522 9797 2 1008.534321 505.2738 T-complex protein 1 subunit epsilon OS=Homo sapiens OX=9606 GN=CCT5 PE=1 SV=1 5.5 2132.2 - 1.83E+06 - - - 1.1859 - 1.481 0.187 - 151.5 1 2 0 0.0012 10 0 0 0 1.62E+09 2.40E+09 - - - 1.518 0.9052 221125_WJC_METTL3_EV_vs_WT_F04.09798.09798.2 0.06 16-Oct R.PSGLLAQER[166.11].K "sp|Q9Y2W1|TR150_HUMAN,tr|A0A3B3ITZ9|A0A3B3ITZ9_HUMAN" 2 979.5326 3.67 44523 9798 2 979.531825 490.7736 Thyroid hormone receptor-associated protein 3 OS=Homo sapiens OX=9606 GN=THRAP3 PE=1 SV=2 6.43 2132.3 - 983817 - - - -0.8055 - 2.067 0.115 - 336.2 1 1 0 -0.0008 9 0 0 0 1.03E+08 2.81E+07 - - - 1.9908 0.9977 221125_WJC_METTL3_EV_vs_WT_F04.09799.09799.2 0.00431 12-Aug R.SNWQNYR[166.11].Q "sp|Q9Y2W1|TR150_HUMAN,tr|A0A3B3ITZ9|A0A3B3ITZ9_HUMAN" 2 976.439 2.46 44524 9799 2 976.439485 489.2268 Thyroid hormone receptor-associated protein 3 OS=Homo sapiens OX=9606 GN=THRAP3 PE=1 SV=2 8.46 2132.3 - 3.06E+06 - - - 0.4475 - 1.296 0.252 - 357.2 1 2 0 0.0004 7 0 0 0 1.36E+09 5.54E+08 - - - 1.7237 0.9998 221125_WJC_METTL3_EV_vs_WT_F04.09806.09806.2 2.76E-05 16-Sep R.YEAAVPDPR.E sp|O43505|B4GA1_HUMAN 1 1016.4927 0.36 44529 9806 2 1016.493905 509.2536 "Beta-1,4-glucuronyltransferase 1 OS=Homo sapiens OX=9606 GN=B4GAT1 PE=1 SV=1" 4.37 2133.2 - 1.44E+06 - - - 1.1756 - 2.169 0.467 - 229.8 1 2 0 0.0012 9 0 0 0 7.84E+07 2.17E+08 - - - 4.7299 0.9993 221125_WJC_METTL3_EV_vs_WT_F04.09807.09807.2 0.00273 18-Nov R.QLESGGFEAR.L sp|Q8IYI6|EXOC8_HUMAN 1 1092.52 2.62 44530 9807 2 1092.516523 547.2673 Exocyst complex component 8 OS=Homo sapiens OX=9606 GN=EXOC8 PE=1 SV=2 4.53 2133.3 - 711680 - - - -3.1707 - 2.033 0.474 - 449 1 2 0 -0.0035 10 0 0 0 3.88E+07 1.48E+07 - - - 4.5213 0.9992 221125_WJC_METTL3_EV_vs_WT_F04.09810.09810.2 0.0066 22-Aug R.YPLAAAAERPPR.L sp|Q7Z5L9|I2BP2_HUMAN 1 1310.7095 2.47 44533 9810 2 1310.710773 656.362 Interferon regulatory factor 2-binding protein 2 OS=Homo sapiens OX=9606 GN=IRF2BP2 PE=1 SV=2 8.75 2133.7 - 170085 - - - 0.9567 - 1.472 0.369 - 88.9 1 2 0 0.0013 12 0 0 0 7.48E+06 3.02E+06 - - - 2.7833 0.9995 221125_WJC_METTL3_EV_vs_WT_F04.09812.09812.2 0.0237 14-Aug K.VC[160.03]NPIITK[136.11].L "sp|P11142|HSP7C_HUMAN,tr|E9PNE6|E9PNE6_HUMAN,tr|A8K7Q2|A8K7Q2_HUMAN,tr|E9PKE3|E9PKE3_HUMAN,tr|E9PS65|E9PS65_HUMAN" 5 951.5303 0.08 44534 9812 2 951.530482 476.7724 Heat shock cognate 71 kDa protein OS=Homo sapiens OX=9606 GN=HSPA8 PE=1 SV=1 8.19 2133.9 - 5.28E+06 - - - 0.2039 - 1.692 0.325 - 216.1 1 2 0 0.0002 8 0 0 0 1.98E+07 2.36E+08 - - - 3.0275 0.9998 221125_WJC_METTL3_EV_vs_WT_F04.09814.09814.2 0.000555 18-Sep K.TALIHDGLAR[166.11].G sp|P25398|RS12_HUMAN 1 1075.6014 1.89 44535 9814 2 1075.601208 538.808 40S ribosomal protein S12 OS=Homo sapiens OX=9606 GN=RPS12 PE=1 SV=3 6.41 2134.1 - 1.78E+07 - - - -0.1441 - 1.895 0.43 - 364.4 1 2 0 -0.0002 10 0 0 0 1.24E+09 6.54E+08 - - - 4.0012 0.9976 221125_WJC_METTL3_EV_vs_WT_F04.09815.09815.2 0.0657 18-Jul R.GC[160.03]VNFEGADR[166.11].L sp|Q8IU81|I2BP1_HUMAN 1 1133.4799 1.63 44536 9815 2 1133.477931 567.7472 Interferon regulatory factor 2-binding protein 1 OS=Homo sapiens OX=9606 GN=IRF2BP1 PE=1 SV=1 4.37 2134.1 - 1.06E+07 - - - -1.7609 - 1.18 0.356 - 103.4 1 2 0 -0.002 10 0 0 0 4.43E+07 2.72E+07 - - - 2.1318 0.9992 221125_WJC_METTL3_EV_vs_WT_F04.09816.09816.2 0.00386 16-Sep R.VNGGLNLSR[166.11].A sp|O15355|PPM1G_HUMAN 1 938.5173 0.53 44537 9816 2 938.515207 470.2659 Protein phosphatase 1G OS=Homo sapiens OX=9606 GN=PPM1G PE=1 SV=1 9.72 2134.2 - 1.44E+06 - - - -2.229 - 1.843 0.372 - 239.1 1 2 0 -0.0021 9 0 0 0 2.06E+07 3.86E+07 - - - 3.5567 0.9974 221125_WJC_METTL3_EV_vs_WT_F04.09817.09817.2 0.139 16-Jun R.VPPPPPIAR.A "sp|P07910|HNRPC_HUMAN,tr|B4DY08|B4DY08_HUMAN,tr|G3V575|G3V575_HUMAN,tr|G3V5V7|G3V5V7_HUMAN,tr|B2R5W2|B2R5W2_HUMAN,tr|G3V4C1|G3V4C1_HUMAN,tr|G3V576|G3V576_HUMAN,tr|G3V2D6|G3V2D6_HUMAN,tr|G3V4W0|G3V4W0_HUMAN,tr|G3V555|G3V555_HUMAN,tr|G3V2Q1|G3V2Q1_HUMAN" 11 942.5651 1.33 44538 9817 2 942.566342 472.2898 Heterogeneous nuclear ribonucleoproteins C1\C2 OS=Homo sapiens OX=9606 GN=HNRNPC PE=1 SV=4 9.72 2134.3 - 943140 - - - 1.3315 - 1.276 0.296 - 128.7 1 2 0 0.0013 9 0 0 0 4.14E+07 3.12E+07 - - - 1.932 0.9985 221125_WJC_METTL3_EV_vs_WT_F04.09818.09818.3 0.363 Aug-36 K.ITHC[160.03]PTLLTR[166.11].D "sp|A6NHR9|SMHD1_HUMAN,tr|A0A2R8YCU7|A0A2R8YCU7_HUMAN,tr|J3KTL8|J3KTL8_HUMAN" 3 1220.6575 1.27 44539 9818 3 1220.658222 407.8931 Structural maintenance of chromosomes flexible hinge domain-containing protein 1 OS=Homo sapiens OX=9606 GN=SMCHD1 PE=1 SV=2 8.26 2134.4 - 533999 - - - 0.5931 - 1.713 0.263 - 80.2 1 2 0 0.0007 10 0 0 0 1.69E+07 1.33E+07 - - - 3.0439 0.9986 221125_WJC_METTL3_EV_vs_WT_F04.09820.09820.2 2.48E-05 22-Nov K.ADAPEGLAPEDR.D sp|Q96T58|MINT_HUMAN 1 1239.5731 0.92 44541 9820 2 1239.568131 620.7938 Msx2-interacting protein OS=Homo sapiens OX=9606 GN=SPEN PE=1 SV=1 3.92 2134.7 - 269466 - - - -4.0449 - 2.026 0.494 - 501.4 1 2 0 -0.005 12 0 0 0 1.39E+07 1.50E+07 - - - 4.5459 0.9998 221125_WJC_METTL3_EV_vs_WT_F04.09824.09824.2 0.000584 22-Nov K.SGVISGGASDLK.A "sp|Q14683|SMC1A_HUMAN,tr|G8JLG1|G8JLG1_HUMAN,tr|A0A6Q8PHC3|A0A6Q8PHC3_HUMAN" 3 1089.5666 1.06 44543 9824 2 1089.565299 545.7906 Structural maintenance of chromosomes protein 1A OS=Homo sapiens OX=9606 GN=SMC1A PE=1 SV=2 5.55 2135.2 - 1.89E+06 - - - -1.1968 - 2.065 0.436 - 371.4 1 2 0 -0.0013 12 0 0 0 1.38E+08 1.30E+08 - - - 4.1688 0.9997 221125_WJC_METTL3_EV_vs_WT_F04.09825.09825.2 0.0221 14-Jul K.SVTYDLSK.L "sp|Q6NZY4|ZCHC8_HUMAN,tr|F5GX80|F5GX80_HUMAN,tr|F5H6J5|F5H6J5_HUMAN" 3 911.46 3 44544 9825 2 911.459493 456.7373 Zinc finger CCHC domain-containing protein 8 OS=Homo sapiens OX=9606 GN=ZCCHC8 PE=1 SV=2 5.55 2135.3 - 1.05E+06 - - - -0.5705 - 1.5 0.436 - 144.4 1 2 0 -0.0005 8 0 0 0 2.01E+07 6.69E+06 - - - 3.484 0.999 221125_WJC_METTL3_EV_vs_WT_F04.09826.09826.2 0.0963 12-Jun R.LASYLDK.V "sp|Q04695|K1C17_HUMAN,sp|Q99456|K1C12_HUMAN,sp|P13645|K1C10_HUMAN,sp|P02533|K1C14_HUMAN,sp|P08727|K1C19_HUMAN,sp|P35527|K1C9_HUMAN,sp|P08779|K1C16_HUMAN,sp|P19012|K1C15_HUMAN,tr|K7EPJ9|K7EPJ9_HUMAN,tr|C9JM50|C9JM50_HUMAN,tr|A0A1B0GVI3|A0A1B0GVI3_HUMAN,tr|A0A3B3ITG2|A0A3B3ITG2_HUMAN" 12 808.4331 64.06 44545 9826 2 808.432425 405.2238 "Keratin, type I cytoskeletal 17 OS=Homo sapiens OX=9606 GN=KRT17 PE=1 SV=2" 5.83 2135.4 - 6.28E+06 - - - -0.7978 - 1.438 0.303 - 113.1 1 2 0 -0.0006 7 0 0 0 1.64E+08 2.56E+06 - - - 2.4297 0.9923 221125_WJC_METTL3_EV_vs_WT_F04.09828.09828.2 0.153 18-Aug K.IESGELDPER.M "sp|P20338|RAB4A_HUMAN,tr|A0A087WYT5|A0A087WYT5_HUMAN" 2 1143.5408 10.8 44547 9828 2 1143.545234 572.7777 Ras-related protein Rab-4A OS=Homo sapiens OX=9606 GN=RAB4A PE=1 SV=3 4 2135.6 - 875585 - - - 3.8932 - 1.632 0.281 - 84.4 1 2 0 0.0045 10 0 0 0 2.15E+08 1.99E+07 - - - 2.4823 0.9999 221125_WJC_METTL3_EV_vs_WT_F04.09829.09829.3 2.67E-07 18/48 K.VPLKEPVTPVAAK.L sp|Q63HK5|TSH3_HUMAN 1 1347.8126 2.63 44548 9829 3 1347.811629 450.2781 Teashirt homolog 3 OS=Homo sapiens OX=9606 GN=TSHZ3 PE=1 SV=2 8.56 2135.7 - 732000 - - - -0.7115 - 2.786 0.523 - 494.8 1 2 1 -0.001 13 0 0 0 1.79E+07 6.80E+06 - - - 7.1487 0.9999 221125_WJC_METTL3_EV_vs_WT_F04.09836.09836.2 5.75E-05 22-Dec K.SGVISGGASDLK[136.11].A "sp|Q14683|SMC1A_HUMAN,tr|G8JLG1|G8JLG1_HUMAN,tr|A0A6Q8PHC3|A0A6Q8PHC3_HUMAN" 3 1097.5808 1.06 44553 9836 2 1097.579604 549.7977 Structural maintenance of chromosomes protein 1A OS=Homo sapiens OX=9606 GN=SMC1A PE=1 SV=2 5.55 2136.7 - 3.99E+06 - - - -1.0924 - 2.569 0.489 - 569.4 1 2 0 -0.0012 12 0 0 0 1.38E+08 1.30E+08 - - - 5.1349 0.9998 221125_WJC_METTL3_EV_vs_WT_F04.09837.09837.2 0.00312 18-Nov R.QLLQEQESVK.Q sp|P15924|DESP_HUMAN 1 1200.635 27.41 44554 9837 2 1200.633626 601.3248 Desmoplakin OS=Homo sapiens OX=9606 GN=DSP PE=1 SV=3 4.53 2136.8 - 1.04E+06 - - - -1.1586 - 2.34 0.396 - 481.1 1 2 0 -0.0014 10 0 0 0 1.90E+08 6.94E+06 - - - 4.3384 0.9997 221125_WJC_METTL3_EV_vs_WT_F04.09838.09838.2 0.00263 16-Oct R.LESEVGHWR[166.11].H "sp|Q15643|TRIPB_HUMAN,tr|G3V4R7|G3V4R7_HUMAN" 2 1121.5493 0.98 44555 9838 2 1121.548779 561.7819 Thyroid receptor-interacting protein 11 OS=Homo sapiens OX=9606 GN=TRIP11 PE=1 SV=3 5.4 2136.9 - 1.03E+06 - - - -0.4886 - 2.121 0.336 - 412.4 1 2 0 -0.0005 9 0 0 0 4.60E+07 4.70E+07 - - - 3.6978 0.9997 221125_WJC_METTL3_EV_vs_WT_F04.09839.09839.2 0.00131 12-Nov K.HILANFK.N "sp|P13693|TCTP_HUMAN,sp|Q56UQ5|TPT1L_HUMAN,tr|H0YCX0|H0YCX0_HUMAN,tr|Q5W0H4|Q5W0H4_HUMAN,tr|A0A0B4J2C3|A0A0B4J2C3_HUMAN,tr|J3KPG2|J3KPG2_HUMAN,tr|E9PJF7|E9PJF7_HUMAN" 7 841.481 1.2 44556 9839 2 841.48011 421.7478 Translationally-controlled tumor protein OS=Homo sapiens OX=9606 GN=TPT1 PE=1 SV=1 8.76 2137 - 1.01E+06 - - - -1.085 - 2.432 0.259 - 512.4 1 2 0 -0.0009 7 0 0 0 4.52E+07 3.77E+07 - - - 3.7696 0.9924 221125_WJC_METTL3_EV_vs_WT_F04.09840.09840.2 0.000523 13/22 H.ALEEANADLEQK.L "sp|Q7Z3Z0|K1C25_HUMAN,sp|Q7Z3Y9|K1C26_HUMAN,sp|Q7Z3Y8|K1C27_HUMAN" 3 1329.6412 999 44557 9840 2 1329.640072 665.8279 "Keratin, type I cytoskeletal 25 OS=Homo sapiens OX=9606 GN=KRT25 PE=1 SV=1" 4 2137.1 - 841766 - - - -0.8672 - 2.705 0.45 - 547.9 1 1 0 -0.0012 12 0 0 0 2.88E+07 0.00E+00 - - - 4.9826 1 221125_WJC_METTL3_EV_vs_WT_F04.09844.09844.3 2.40E-05 Dec-36 K.MNGMLLNDRK.V "sp|Q13310|PABP4_HUMAN,sp|Q4VXU2|PAP1L_HUMAN,sp|P11940|PABP1_HUMAN,tr|A0A7I2V5W9|A0A7I2V5W9_HUMAN,tr|A0A7I2YQE4|A0A7I2YQE4_HUMAN,tr|A0A7I2V649|A0A7I2V649_HUMAN,tr|B1ANR0|B1ANR0_HUMAN,tr|A0A6Q8JFT6|A0A6Q8JFT6_HUMAN,tr|A0A7I2V4L7|A0A7I2V4L7_HUMAN,tr|H0YCC8|H0YCC8_HUMAN,tr|H0YAR2|H0YAR2_HUMAN,tr|E7ERJ7|E7ERJ7_HUMAN,tr|A0A7I2V598|A0A7I2V598_HUMAN,tr|A0A7I2YQ88|A0A7I2YQ88_HUMAN,tr|H0YEQ8|H0YEQ8_HUMAN,tr|H0Y5F5|H0Y5F5_HUMAN,tr|H0YBN4|H0YBN4_HUMAN,tr|A0A087WTT1|A0A087WTT1_HUMAN,tr|A0A7I2YQ90|A0A7I2YQ90_HUMAN,tr|A0A7I2V4N4|A0A7I2V4N4_HUMAN,tr|E7EQV3|E7EQV3_HUMAN" 21 1190.59 1.26 44559 9844 3 1190.589258 397.8706 Polyadenylate-binding protein 4 OS=Homo sapiens OX=9606 GN=PABPC4 PE=1 SV=1 8.5 2137.7 - 2.48E+06 - - - -0.6215 - 2.269 0.474 - 184.9 1 2 0 -0.0007 10 0 0 0 9.79E+07 7.76E+07 - - - 6.2173 0.9995 221125_WJC_METTL3_EV_vs_WT_F04.09845.09845.2 0.0021 18-Oct R.QLESGGFEAR[166.11].L sp|Q8IYI6|EXOC8_HUMAN 1 1102.5283 2.65 44560 9845 2 1102.527091 552.2714 Exocyst complex component 8 OS=Homo sapiens OX=9606 GN=EXOC8 PE=1 SV=2 4.53 2137.7 - 1.43E+06 - - - -1.0576 - 1.529 0.405 - 270.3 1 2 0 -0.0012 10 0 0 0 3.85E+07 1.46E+07 - - - 3.2172 0.8347 221125_WJC_METTL3_EV_vs_WT_F04.09846.09846.2 1.91 14-Jun R.NYFQPSTK.K "sp|O60934|NBN_HUMAN,tr|A0A0C4DG07|A0A0C4DG07_HUMAN" 2 983.4712 0.08 44561 9846 2 983.469206 492.7429 Nibrin OS=Homo sapiens OX=9606 GN=NBN PE=1 SV=1 8.59 2137.9 - 440324 - - - -2.0743 - 1.03 0.035 - 81.3 2 2 0 -0.002 8 0 0 0 7.33E+06 9.22E+07 - - - -0.7465 0.9986 221125_WJC_METTL3_EV_vs_WT_F04.09848.09848.2 0.0872 16-Oct K.LAQFEPSQR[166.11].Q sp|Q08211|DHX9_HUMAN 1 1084.5541 0.97 44562 9848 2 1084.552384 543.2843 ATP-dependent RNA helicase A OS=Homo sapiens OX=9606 GN=DHX9 PE=1 SV=4 6 2138.1 - 1.43E+07 - - - -1.5619 - 1.725 0.25 - 501.2 1 2 0 -0.0017 9 0 0 0 4.58E+08 4.73E+08 - - - 2.4643 0.9837 221125_WJC_METTL3_EV_vs_WT_F04.09850.09850.2 0.00338 16-Sep R.QQAADLISR[166.11].T sp|O75533|SF3B1_HUMAN 1 1010.5384 1.62 44563 9850 2 1010.541638 506.2765 Splicing factor 3B subunit 1 OS=Homo sapiens OX=9606 GN=SF3B1 PE=1 SV=3 5.84 2138.3 - 1.02E+07 - - - 3.1765 - 1.519 0.161 - 237.9 1 2 0 0.0032 9 0 0 0 3.51E+08 2.17E+08 - - - 1.4386 0.8177 221125_WJC_METTL3_EV_vs_WT_F04.09851.09851.2 0.111 14-Aug T.EELAYLRK.N "sp|Q2M2I5|K1C24_HUMAN,sp|P08779|K1C16_HUMAN,tr|K7ENW6|K7ENW6_HUMAN" 3 1020.5604 43.21 44564 9851 2 1020.559802 511.2875 "Keratin, type I cytoskeletal 24 OS=Homo sapiens OX=9606 GN=KRT24 PE=1 SV=1" 6.24 2138.4 - 1.24E+06 - - - -0.5811 - 1.459 0.159 - 237.7 1 1 0 -0.0006 8 0 0 0 2.41E+07 5.58E+05 - - - 1.3545 0.9873 221125_WJC_METTL3_EV_vs_WT_F04.09852.09852.2 0.0619 18-Aug R.TSLGPNGLDK.M "sp|P48643|TCPE_HUMAN,tr|E9PCA1|E9PCA1_HUMAN,tr|B7ZAR1|B7ZAR1_HUMAN" 3 1000.5189 0.67 44565 9852 2 1000.523584 501.2667 T-complex protein 1 subunit epsilon OS=Homo sapiens OX=9606 GN=CCT5 PE=1 SV=1 5.5 2138.4 - 1.32E+07 - - - 4.6566 - 1.709 0.271 - 177.8 1 2 0 0.0047 10 0 0 0 1.62E+09 2.40E+09 - - - 2.537 0.9996 221125_WJC_METTL3_EV_vs_WT_F04.09855.09855.2 0.0277 22-Sep K.VVVHQETEIADE.- "sp|P11171|EPB41_HUMAN,tr|A0A3B3ITP0|A0A3B3ITP0_HUMAN,tr|A0A2U3TZH6|A0A2U3TZH6_HUMAN,tr|A0A2R8Y7Y3|A0A2R8Y7Y3_HUMAN,tr|A0A2R8YD30|A0A2R8YD30_HUMAN" 5 1367.6569 - 44566 9855 2 1367.654049 684.8357 Protein 4.1 OS=Homo sapiens OX=9606 GN=EPB41 PE=1 SV=4 4.24 2138.8 - 324370 - - - -2.0663 - 2.086 0.443 - 272.1 1 2 0 -0.0028 12 0 0 0 - - - - - 4.2467 0.9997 221125_WJC_METTL3_EV_vs_WT_F04.09862.09862.2 0.00745 20-Aug R.GLPNGMDADC[160.03]K[136.11].D "sp|Q8TB72|PUM2_HUMAN,tr|A0A0C4DG68|A0A0C4DG68_HUMAN,tr|C9JW01|C9JW01_HUMAN" 3 1184.5045 1.15 44568 9862 2 1184.50289 593.2595 Pumilio homolog 2 OS=Homo sapiens OX=9606 GN=PUM2 PE=1 SV=2 4.21 2139.8 - 275948 - - - -1.3964 - 1.664 0.486 - 112.8 1 2 0 -0.0017 11 0 0 0 7.30E+06 6.34E+06 - - - 4.0076 0.9997 221125_WJC_METTL3_EV_vs_WT_F04.09864.09864.2 0.00167 18-Aug K.LLNTVEETTK.D "sp|P52732|KIF11_HUMAN,tr|A0A7I2YQY4|A0A7I2YQY4_HUMAN,tr|A0A7I2V3A9|A0A7I2V3A9_HUMAN" 3 1146.6132 4.13 44569 9864 2 1146.612252 574.3139 Kinesin-like protein KIF11 OS=Homo sapiens OX=9606 GN=KIF11 PE=1 SV=2 4.53 2140 - 1.50E+06 - - - -0.8434 - 1.659 0.464 - 150.1 1 2 0 -0.001 10 0 0 0 4.05E+07 9.83E+06 - - - 3.8808 0.9978 221125_WJC_METTL3_EV_vs_WT_F04.09867.09867.2 0.0026 14-Aug R.NYDYYASR.V sp|O95861|BPNT1_HUMAN 1 1050.4407 0.73 44570 9867 2 1050.436433 526.2276 "3'(2'),5'-bisphosphate nucleotidase 1 OS=Homo sapiens OX=9606 GN=BPNT1 PE=1 SV=1" 5.83 2140.4 - 674608 - - - -4.0374 - 1.455 0.506 - 295.3 1 2 0 -0.0042 8 0 0 0 1.40E+07 1.92E+07 - - - 3.908 0.906 221125_WJC_METTL3_EV_vs_WT_F04.09868.09868.2 0.156 12-Jul E.SEVGHWR[166.11].H "sp|Q15643|TRIPB_HUMAN,tr|G3V4R7|G3V4R7_HUMAN" 2 879.4227 0.64 44571 9868 2 879.422215 440.7186 Thyroid receptor-interacting protein 11 OS=Homo sapiens OX=9606 GN=TRIP11 PE=1 SV=3 6.47 2140.5 - 648984 - - - -0.5174 - 1.424 0.24 - 376.9 1 1 0 -0.0005 7 0 0 0 7.75E+06 1.21E+07 - - - 1.9335 0.9445 221125_WJC_METTL3_EV_vs_WT_F04.09871.09871.2 1.67 20-Apr K.IFPYEEYASWK.T sp|P37173|TGFR2_HUMAN 1 1431.6711 999 44574 9871 2 1431.668378 716.8428 TGF-beta receptor type-2 OS=Homo sapiens OX=9606 GN=TGFBR2 PE=1 SV=2 4.53 2140.9 - 199571 - - - -1.8789 - 1.087 0.107 - 47.4 2 2 0 -0.0027 11 0 0 0 3.14E+06 0.00E+00 - - - -0.0783 1 221125_WJC_METTL3_EV_vs_WT_F04.09873.09873.3 0.000497 14/44 R.YPLAAAAERPPR.L sp|Q7Z5L9|I2BP2_HUMAN 1 1310.7095 1.58 44575 9873 3 1310.708727 437.9104 Interferon regulatory factor 2-binding protein 2 OS=Homo sapiens OX=9606 GN=IRF2BP2 PE=1 SV=2 8.75 2141.1 - 4.22E+06 - - - -0.6043 - 2.529 0.483 - 271.7 1 2 0 -0.0008 12 0 0 0 1.19E+08 7.52E+07 - - - 6.4965 0.9999 221125_WJC_METTL3_EV_vs_WT_F04.09875.09875.3 2.68E-05 13/36 K.MNGMLLNDR[166.11]K[136.11].V "sp|Q13310|PABP4_HUMAN,sp|Q4VXU2|PAP1L_HUMAN,sp|P11940|PABP1_HUMAN,tr|A0A7I2V5W9|A0A7I2V5W9_HUMAN,tr|A0A7I2YQE4|A0A7I2YQE4_HUMAN,tr|A0A7I2V649|A0A7I2V649_HUMAN,tr|B1ANR0|B1ANR0_HUMAN,tr|A0A6Q8JFT6|A0A6Q8JFT6_HUMAN,tr|A0A7I2V4L7|A0A7I2V4L7_HUMAN,tr|H0YCC8|H0YCC8_HUMAN,tr|H0YAR2|H0YAR2_HUMAN,tr|E7ERJ7|E7ERJ7_HUMAN,tr|A0A7I2V598|A0A7I2V598_HUMAN,tr|A0A7I2YQ88|A0A7I2YQ88_HUMAN,tr|H0YEQ8|H0YEQ8_HUMAN,tr|H0Y5F5|H0Y5F5_HUMAN,tr|H0YBN4|H0YBN4_HUMAN,tr|A0A087WTT1|A0A087WTT1_HUMAN,tr|A0A7I2YQ90|A0A7I2YQ90_HUMAN,tr|A0A7I2V4N4|A0A7I2V4N4_HUMAN,tr|E7EQV3|E7EQV3_HUMAN" 21 1208.6125 1.26 44577 9875 3 1208.611626 403.8781 Polyadenylate-binding protein 4 OS=Homo sapiens OX=9606 GN=PABPC4 PE=1 SV=1 8.5 2141.3 - 3.97E+06 - - - -0.6967 - 2.049 0.458 - 222 1 2 0 -0.0008 10 0 0 0 9.79E+07 7.76E+07 - - - 5.741 0.9989 221125_WJC_METTL3_EV_vs_WT_F04.09877.09877.2 0.0155 12-Sep K.HILANFK[136.11].N "sp|P13693|TCTP_HUMAN,sp|Q56UQ5|TPT1L_HUMAN,tr|H0YCX0|H0YCX0_HUMAN,tr|Q5W0H4|Q5W0H4_HUMAN,tr|A0A0B4J2C3|A0A0B4J2C3_HUMAN,tr|J3KPG2|J3KPG2_HUMAN,tr|E9PJF7|E9PJF7_HUMAN" 7 849.4952 1.21 44579 9877 2 849.494347 425.7549 Translationally-controlled tumor protein OS=Homo sapiens OX=9606 GN=TPT1 PE=1 SV=1 8.76 2141.5 - 1.41E+06 - - - -1.0312 - 1.414 0.311 - 214.8 1 2 0 -0.0009 7 0 0 0 4.51E+07 3.72E+07 - - - 2.4354 0.9995 221125_WJC_METTL3_EV_vs_WT_F04.09879.09879.2 0.0026 16-Sep R.VPPPPPIAR[166.11].A "sp|P07910|HNRPC_HUMAN,tr|B4DY08|B4DY08_HUMAN,tr|G3V575|G3V575_HUMAN,tr|G3V5V7|G3V5V7_HUMAN,tr|B2R5W2|B2R5W2_HUMAN,tr|G3V4C1|G3V4C1_HUMAN,tr|G3V576|G3V576_HUMAN,tr|G3V2D6|G3V2D6_HUMAN,tr|G3V4W0|G3V4W0_HUMAN,tr|G3V555|G3V555_HUMAN,tr|G3V2Q1|G3V2Q1_HUMAN" 11 952.5734 1.53 44581 9879 2 952.573709 477.294 Heterogeneous nuclear ribonucleoproteins C1\C2 OS=Homo sapiens OX=9606 GN=HNRNPC PE=1 SV=4 9.72 2141.7 - 731668 - - - 0.3695 - 1.591 0.373 - 294 1 2 0 0.0004 9 0 0 0 4.02E+07 2.62E+07 - - - 3.1393 0.9147 221125_WJC_METTL3_EV_vs_WT_F04.09880.09880.2 0.0273 18-Aug N.GAGGALFVHR[166.11].D "sp|P19404|NDUV2_HUMAN,tr|E7EPT4|E7EPT4_HUMAN" 2 993.5384 0.8 44582 9880 2 993.53991 497.7765 "NADH dehydrogenase [ubiquinone] flavoprotein 2, mitochondrial OS=Homo sapiens OX=9606 GN=NDUFV2 PE=1 SV=2" 9.76 2141.8 - 572777 - - - 1.552 - 1.66 0.275 - 150.9 1 1 0 0.0015 10 0 0 0 9.10E+06 1.13E+07 - - - 2.4863 0.9981 221125_WJC_METTL3_EV_vs_WT_F04.09881.09881.2 7.24E-07 22-Sep R.C[160.03]AADAGRPPGEL.- "sp|Q8NBJ7|SUMF2_HUMAN,tr|A8MXB9|A8MXB9_HUMAN,tr|E9PBT8|E9PBT8_HUMAN,tr|J3KQJ1|J3KQJ1_HUMAN,tr|J3QT17|J3QT17_HUMAN,tr|A0A494C1B1|A0A494C1B1_HUMAN" 6 1212.5557 1.69 44583 9881 2 1212.549698 607.2851 Inactive C-alpha-formylglycine-generating enzyme 2 OS=Homo sapiens OX=9606 GN=SUMF2 PE=1 SV=2 4.37 2141.9 - 401369 - - - -4.9672 - 1.994 0.586 - 189.5 1 2 0 -0.006 12 0 0 0 1.33E+07 7.88E+06 - - - 5.1832 0.9992 221125_WJC_METTL3_EV_vs_WT_F04.09882.09882.2 0.205 18-Aug R.IQETQAELPR.G sp|Q14566|MCM6_HUMAN 1 1183.6197 0.92 44584 9882 2 1183.619711 592.8171 DNA replication licensing factor MCM6 OS=Homo sapiens OX=9606 GN=MCM6 PE=1 SV=1 4.53 2142.1 - 257717 - - - 0.0084 - 1.709 0.276 - 167.6 1 2 0 0 10 0 0 0 1.60E+07 1.74E+07 - - - 2.5754 0.9998 221125_WJC_METTL3_EV_vs_WT_F04.09886.09886.2 0.00454 18-Oct R.IQETQAELPR[166.11].G sp|Q14566|MCM6_HUMAN 1 1193.628 0.93 44586 9886 2 1193.627789 597.8213 DNA replication licensing factor MCM6 OS=Homo sapiens OX=9606 GN=MCM6 PE=1 SV=1 4.53 2142.6 - 607403 - - - -0.1525 - 2.008 0.392 - 337.5 1 2 0 -0.0002 10 0 0 0 1.61E+07 1.74E+07 - - - 3.8822 0.9966 221125_WJC_METTL3_EV_vs_WT_F04.09895.09895.2 0.00127 12-Sep K.IRDWYQR.Q "sp|Q04695|K1C17_HUMAN,sp|P02533|K1C14_HUMAN,sp|P08779|K1C16_HUMAN,tr|K7EPJ9|K7EPJ9_HUMAN,tr|F5GWP8|F5GWP8_HUMAN" 5 1035.525 448.02 44594 9895 2 1035.524672 518.7698 "Keratin, type I cytoskeletal 17 OS=Homo sapiens OX=9606 GN=KRT17 PE=1 SV=2" 8.75 2143.7 - 2.11E+07 - - - -0.3293 - 1.87 0.345 - 239.6 1 2 1 -0.0003 7 0 0 0 1.39E+09 3.11E+06 - - - 3.5724 0.9991 221125_WJC_METTL3_EV_vs_WT_F04.09896.09896.2 0.00513 12-Aug R.SNWQNYR.Q "sp|Q9Y2W1|TR150_HUMAN,tr|A0A3B3ITZ9|A0A3B3ITZ9_HUMAN" 2 966.4308 2.46 44595 9896 2 966.430543 484.2227 Thyroid hormone receptor-associated protein 3 OS=Homo sapiens OX=9606 GN=THRAP3 PE=1 SV=2 8.46 2143.7 - 7.93E+06 - - - -0.2432 - 1.311 0.35 - 400.2 1 2 0 -0.0002 7 0 0 0 1.36E+09 5.54E+08 - - - 2.484 0.9997 221125_WJC_METTL3_EV_vs_WT_F04.09898.09898.2 0.011 18-Sep R.VTVVDVNESR.L "sp|O60701|UGDH_HUMAN,tr|E9PBD2|E9PBD2_HUMAN,tr|D6RHF4|D6RHF4_HUMAN,tr|E7EV97|E7EV97_HUMAN,tr|E7ER83|E7ER83_HUMAN,tr|E7ER95|E7ER95_HUMAN,tr|E7ETF4|E7ETF4_HUMAN" 7 1116.5775 7.82 44597 9898 2 1116.578295 559.296 UDP-glucose 6-dehydrogenase OS=Homo sapiens OX=9606 GN=UGDH PE=1 SV=1 4.37 2143.9 - 1.17E+06 - - - 0.7102 - 1.958 0.408 - 376.5 1 2 0 0.0008 10 0 0 0 4.73E+07 6.05E+06 - - - 3.9298 0.9998 221125_WJC_METTL3_EV_vs_WT_F04.09902.09902.2 0.0295 16-Oct K.LAQFEPSQR.Q sp|Q08211|DHX9_HUMAN 1 1074.5458 0.96 44600 9902 2 1074.545808 538.2802 ATP-dependent RNA helicase A OS=Homo sapiens OX=9606 GN=DHX9 PE=1 SV=4 6 2144.4 - 1.00E+07 - - - 0 - 1.967 0.388 - 480.5 1 2 0 0 9 0 0 0 4.54E+08 4.72E+08 - - - 3.8639 0.9966 221125_WJC_METTL3_EV_vs_WT_F04.09904.09904.2 0.126 14-Jun K.SYPSLTTK.V sp|Q15029|U5S1_HUMAN 1 895.4651 2.19 44602 9904 2 895.464883 448.7398 116 kDa U5 small nuclear ribonucleoprotein component OS=Homo sapiens OX=9606 GN=EFTUD2 PE=1 SV=1 8.31 2144.6 - 1.96E+06 - - - -0.2401 - 0.923 0.35 - 92.7 1 2 0 -0.0002 8 0 0 0 5.13E+07 2.35E+07 - - - 1.3844 0.9859 221125_WJC_METTL3_EV_vs_WT_F04.09905.09905.2 0.463 14-Jul K.SYPSLTTK[136.11].V sp|Q15029|U5S1_HUMAN 1 903.4793 2.19 44603 9905 2 903.478466 452.7469 116 kDa U5 small nuclear ribonucleoprotein component OS=Homo sapiens OX=9606 GN=EFTUD2 PE=1 SV=1 8.31 2144.6 - 849190 - - - -0.9209 - 1.044 0.178 - 128.4 1 2 0 -0.0008 8 0 0 0 5.13E+07 2.35E+07 - - - 0.4853 0.9998 221125_WJC_METTL3_EV_vs_WT_F04.09906.09906.2 0.00147 20-Dec K.NADLNAQTVVK[136.11].V "sp|Q9Y520|PRC2C_HUMAN,tr|E7EPN9|E7EPN9_HUMAN,tr|H7C5N8|H7C5N8_HUMAN" 3 1179.6339 0.73 44604 9906 2 1179.632732 590.8242 Protein PRRC2C OS=Homo sapiens OX=9606 GN=PRRC2C PE=1 SV=4 5.84 2144.8 - 638899 - - - -0.991 - 2.578 0.421 - 574.9 1 2 0 -0.0012 11 0 0 0 4.25E+07 5.81E+07 - - - 4.712 0.9995 221125_WJC_METTL3_EV_vs_WT_F04.09912.09912.2 0.000297 18-Sep R.ASAVSELSPR[166.11].E "sp|Q9Y2W1|TR150_HUMAN,tr|A0A3B3ITZ9|A0A3B3ITZ9_HUMAN" 2 1025.5381 2.61 44608 9912 2 1025.5372 513.7763 Thyroid hormone receptor-associated protein 3 OS=Homo sapiens OX=9606 GN=THRAP3 PE=1 SV=2 6.05 2145.6 - 502179 - - - -0.8717 - 1.864 0.325 - 297.5 1 2 0 -0.0009 10 0 0 0 6.61E+09 2.53E+09 - - - 3.1794 0.9993 221125_WJC_METTL3_EV_vs_WT_F04.09917.09917.2 0.00783 14-Jun R.EFIQEPAK[136.11].N "sp|O14744|ANM5_HUMAN,tr|C9JSX3|C9JSX3_HUMAN,tr|G3V580|G3V580_HUMAN,tr|G3V2L6|G3V2L6_HUMAN,tr|G3V5L5|G3V5L5_HUMAN" 5 968.5058 3.02 44611 9917 2 968.505789 485.2602 Protein arginine N-methyltransferase 5 OS=Homo sapiens OX=9606 GN=PRMT5 PE=1 SV=4 4.53 2146.2 - 3.14E+06 - - - -0.0599 - 1.312 0.386 - 126.5 1 2 0 -0.0001 8 0 0 0 1.69E+08 5.61E+07 - - - 2.711 0.9995 221125_WJC_METTL3_EV_vs_WT_F04.09918.09918.2 0.0264 16-Nov K.QEELVQQVR[166.11].K "sp|O95983|MBD3_HUMAN,tr|K7EIE8|K7EIE8_HUMAN" 2 1137.6018 0.61 44612 9918 2 1137.604319 569.8082 Methyl-CpG-binding domain protein 3 OS=Homo sapiens OX=9606 GN=MBD3 PE=1 SV=1 4.53 2146.3 - 1.43E+06 - - - 2.2521 - 2.169 0.386 - 679.5 1 2 0 0.0026 9 0 0 0 1.98E+07 3.23E+07 - - - 4.1312 0.9998 221125_WJC_METTL3_EV_vs_WT_F04.09921.09921.2 5.74E-10 20-Dec R.FEDVVNQSSPK[136.11].N sp|Q01085|TIAR_HUMAN 1 1256.6128 1.56 44615 9921 2 1256.610859 629.3137 Nucleolysin TIAR OS=Homo sapiens OX=9606 GN=TIAL1 PE=1 SV=1 4.37 2146.7 - 421821 - - - -1.5701 - 2.377 0.538 - 425 1 2 0 -0.002 11 0 0 0 5.66E+07 3.62E+07 - - - 5.3563 0.9844 221125_WJC_METTL3_EV_vs_WT_F04.09926.09926.2 2.88 16-Jul K.R[166.11]LNVTPLAR[166.11].L "sp|P24752|THIL_HUMAN,tr|A0A5F9ZHJ7|A0A5F9ZHJ7_HUMAN,tr|A0A5F9ZHD4|A0A5F9ZHD4_HUMAN,tr|A0A5F9ZHJ0|A0A5F9ZHJ0_HUMAN,tr|A0A5F9ZHL1|A0A5F9ZHL1_HUMAN,tr|A0A5F9ZI66|A0A5F9ZI66_HUMAN" 6 1058.6464 1.28 44618 9926 2 1058.646145 530.3305 "Acetyl-CoA acetyltransferase, mitochondrial OS=Homo sapiens OX=9606 GN=ACAT1 PE=1 SV=1" 12 2147.3 - 1.53E+06 - - - -0.1955 - 1.147 0.119 - 72.3 1 2 0 -0.0002 9 0 0 0 9.07E+07 7.11E+07 - - - 0.3167 0.9997 221125_WJC_METTL3_EV_vs_WT_F04.09930.09930.2 0.0279 16-Nov K.RLNVTPLAR.L "sp|P24752|THIL_HUMAN,tr|A0A5F9ZHJ7|A0A5F9ZHJ7_HUMAN,tr|A0A5F9ZHD4|A0A5F9ZHD4_HUMAN,tr|A0A5F9ZHJ0|A0A5F9ZHJ0_HUMAN,tr|A0A5F9ZHL1|A0A5F9ZHL1_HUMAN,tr|A0A5F9ZI66|A0A5F9ZI66_HUMAN" 6 1038.6298 1.28 44620 9930 2 1038.628982 520.3222 "Acetyl-CoA acetyltransferase, mitochondrial OS=Homo sapiens OX=9606 GN=ACAT1 PE=1 SV=1" 12 2147.8 - 2.22E+06 - - - -0.7991 - 2.041 0.33 - 215.2 1 2 0 -0.0008 9 0 0 0 9.07E+07 7.11E+07 - - - 3.5421 0.9989 221125_WJC_METTL3_EV_vs_WT_F04.09932.09932.3 0.00495 13/36 K.LFKPPQPPAR.M "sp|O15372|EIF3H_HUMAN,tr|B3KS98|B3KS98_HUMAN,tr|A0A087WZK9|A0A087WZK9_HUMAN" 3 1149.6659 1.44 44622 9932 3 1149.66302 384.2292 Eukaryotic translation initiation factor 3 subunit H OS=Homo sapiens OX=9606 GN=EIF3H PE=1 SV=1 11 2148 - 580282 - - - -2.4738 - 1.978 0.308 - 230.4 1 2 0 -0.0028 10 0 0 0 7.88E+06 5.48E+06 - - - 3.9651 1 221125_WJC_METTL3_EV_vs_WT_F04.09935.09935.3 1.32E-05 Dec-44 R.YPLAAAAER[166.11]PPR[166.11].L sp|Q7Z5L9|I2BP2_HUMAN 1 1330.7261 1.62 44624 9935 3 1330.725912 444.5826 Interferon regulatory factor 2-binding protein 2 OS=Homo sapiens OX=9606 GN=IRF2BP2 PE=1 SV=2 8.75 2148.3 - 2.86E+06 - - - -0.1105 - 2.039 0.504 - 198.4 1 2 0 -0.0001 12 0 0 0 1.71E+08 1.06E+08 - - - 6.1339 0.9987 221125_WJC_METTL3_EV_vs_WT_F04.09942.09942.2 0.000982 18-Nov R.ASAVSELSPR.E "sp|Q9Y2W1|TR150_HUMAN,tr|A0A3B3ITZ9|A0A3B3ITZ9_HUMAN" 2 1015.5298 2.61 44629 9942 2 1015.527426 508.7722 Thyroid hormone receptor-associated protein 3 OS=Homo sapiens OX=9606 GN=THRAP3 PE=1 SV=2 6.05 2149.1 - 3.82E+06 - - - -2.3613 - 2.34 0.224 - 566.3 1 2 0 -0.0024 10 0 0 0 6.60E+09 2.53E+09 - - - 3.0677 0.9995 221125_WJC_METTL3_EV_vs_WT_F04.09943.09943.2 0.00544 16-Sep R.AGVSQVLNR.L "sp|P30876|RPB2_HUMAN,tr|C9J4M6|C9J4M6_HUMAN,tr|C9J2Y9|C9J2Y9_HUMAN" 3 942.5247 0.92 44630 9943 2 942.524545 472.2696 DNA-directed RNA polymerase II subunit RPB2 OS=Homo sapiens OX=9606 GN=POLR2B PE=1 SV=1 9.79 2149.2 - 2.23E+06 - - - -0.1422 - 1.739 0.333 - 318 1 2 0 -0.0001 9 0 0 0 3.53E+07 3.83E+07 - - - 3.1013 0.9873 221125_WJC_METTL3_EV_vs_WT_F04.09944.09944.2 0.0655 18-Aug K.AAPPQIPDTR.R sp|Q9HAF1|EAF6_HUMAN 1 1064.5615 2.61 44631 9944 2 1064.564569 533.288 Chromatin modification-related protein MEAF6 OS=Homo sapiens OX=9606 GN=MEAF6 PE=1 SV=1 5.88 2149.3 - 1.43E+06 - - - 2.9223 - 1.428 0.197 - 171.5 1 2 0 0.0031 10 0 0 0 3.60E+07 1.38E+07 - - - 1.4895 0.9963 221125_WJC_METTL3_EV_vs_WT_F04.09946.09946.2 0.0191 14-Sep K.TDNTVPFK.T sp|Q9Y5B6|PAXB1_HUMAN 1 920.4603 0.12 44633 9946 2 920.4632 461.2374 PAX3- and PAX7-binding protein 1 OS=Homo sapiens OX=9606 GN=PAXBP1 PE=1 SV=2 5.5 2149.5 - 504185 - - - 3.0995 - 1.65 0.282 - 362.3 1 2 0 0.0029 8 0 0 0 9.06E+06 7.64E+07 - - - 2.6333 0.9984 221125_WJC_METTL3_EV_vs_WT_F04.09947.09947.2 0.0206 18-Aug R.GLDNTEFQGK.R "sp|Q9BWF3|RBM4_HUMAN,sp|Q9BQ04|RBM4B_HUMAN,tr|E9PB51|E9PB51_HUMAN" 3 1107.5197 1.01 44634 9947 2 1107.517815 554.7671 RNA-binding protein 4 OS=Homo sapiens OX=9606 GN=RBM4 PE=1 SV=1 4.37 2149.6 - 358109 - - - -1.6596 - 1.347 0.345 - 164.4 1 2 0 -0.0018 10 0 0 0 2.31E+06 2.29E+06 - - - 2.4201 0.9981 221125_WJC_METTL3_EV_vs_WT_F04.09948.09948.2 0.328 20-Jul K.DIQEDSGMEPR[166.11].N sp|O75844|FACE1_HUMAN 1 1285.5484 1.19 44635 9948 2 1285.547024 643.7815 CAAX prenyl protease 1 homolog OS=Homo sapiens OX=9606 GN=ZMPSTE24 PE=1 SV=2 3.92 2149.7 - 276419 - - - -1.0704 - 1.21 0.332 - 49.7 1 2 0 -0.0014 11 0 0 0 6.28E+06 5.28E+06 - - - 2.0084 0.9997 221125_WJC_METTL3_EV_vs_WT_F04.09951.09951.2 0.00326 18-Aug R.TSLGPNGLDK.M "sp|P48643|TCPE_HUMAN,tr|E9PCA1|E9PCA1_HUMAN,tr|B7ZAR1|B7ZAR1_HUMAN" 3 1000.5189 0.67 44637 9951 2 1000.519437 501.2667 T-complex protein 1 subunit epsilon OS=Homo sapiens OX=9606 GN=CCT5 PE=1 SV=1 5.5 2150.1 - 4.51E+07 - - - 0.5117 - 1.708 0.452 - 193.6 1 2 0 0.0005 10 0 0 0 1.62E+09 2.40E+09 - - - 3.8736 0.9997 221125_WJC_METTL3_EV_vs_WT_F04.09952.09952.2 0.0894 18-Sep R.AGEVQEPELR.G sp|P25311|ZA2G_HUMAN 1 1126.5619 34.76 44638 9952 2 1126.561609 564.2882 Zinc-alpha-2-glycoprotein OS=Homo sapiens OX=9606 GN=AZGP1 PE=1 SV=2 4.25 2150.1 - 1.67E+07 - - - -0.2157 - 2.082 0.353 - 419.7 1 2 0 -0.0002 10 0 0 0 4.82E+08 1.39E+07 - - - 3.6951 0.9998 221125_WJC_METTL3_EV_vs_WT_F04.09956.09956.2 0.000954 20-Nov K.QLIVANAGDSR[166.11].C sp|O15355|PPM1G_HUMAN 1 1152.6127 0.74 44642 9956 2 1152.612214 577.3136 Protein phosphatase 1G OS=Homo sapiens OX=9606 GN=PPM1G PE=1 SV=1 5.84 2150.5 - 706368 - - - -0.3835 - 2.319 0.371 - 514 1 2 0 -0.0004 11 0 0 0 2.98E+07 4.02E+07 - - - 4.0565 0.9998 221125_WJC_METTL3_EV_vs_WT_F04.09959.09959.2 2.61E-06 22-Dec R.VAEELALEQAK[136.11]K[136.11].E "sp|Q9NX63|MIC19_HUMAN,tr|A0A286YEX5|A0A286YEX5_HUMAN,tr|F8WAR4|F8WAR4_HUMAN,tr|C9JRZ6|C9JRZ6_HUMAN" 4 1343.7631 1.95 44645 9959 2 1343.76077 672.8888 MICOS complex subunit MIC19 OS=Homo sapiens OX=9606 GN=CHCHD3 PE=1 SV=1 4.79 2150.9 - 183471 - - - -1.757 - 2.583 0.428 - 474.4 1 2 0 -0.0024 12 0 0 0 5.96E+06 3.05E+06 - - - 4.6983 0.9508 221125_WJC_METTL3_EV_vs_WT_F04.09962.09962.2 0.628 18-Jul R.DLHTLDSHVR[166.11].G "sp|Q5T4S7|UBR4_HUMAN,tr|A0A0A0MSW0|A0A0A0MSW0_HUMAN,tr|X6RE05|X6RE05_HUMAN" 3 1201.6079 0 44646 9962 2 1201.610444 601.8112 E3 ubiquitin-protein ligase UBR4 OS=Homo sapiens OX=9606 GN=UBR4 PE=1 SV=1 5.98 2151.3 - 2.07E+06 - - - 2.113 - 1.341 0.068 - 186.7 3 2 0 0.0025 10 0 0 0 3.69E+05 1.04E+08 - - - 0.1483 0.9999 221125_WJC_METTL3_EV_vs_WT_F04.09963.09963.3 0.00036 13/44 R.VAEELALEQAK[136.11]K[136.11].E "sp|Q9NX63|MIC19_HUMAN,tr|A0A286YEX5|A0A286YEX5_HUMAN,tr|F8WAR4|F8WAR4_HUMAN,tr|C9JRZ6|C9JRZ6_HUMAN" 4 1343.7631 1.8 44647 9963 3 1343.762586 448.9283 MICOS complex subunit MIC19 OS=Homo sapiens OX=9606 GN=CHCHD3 PE=1 SV=1 4.79 2151.3 - 1.98E+06 - - - -0.4056 - 2.213 0.37 - 187.4 1 2 0 -0.0005 12 0 0 0 4.91E+07 2.72E+07 - - - 4.8668 0.9202 221125_WJC_METTL3_EV_vs_WT_F04.09964.09964.3 3.45 Aug-36 R.DLHTLDSHVR[166.11].G "sp|Q5T4S7|UBR4_HUMAN,tr|A0A0A0MSW0|A0A0A0MSW0_HUMAN,tr|X6RE05|X6RE05_HUMAN" 3 1201.6079 0.02 44648 9964 3 1201.609284 401.5432 E3 ubiquitin-protein ligase UBR4 OS=Homo sapiens OX=9606 GN=UBR4 PE=1 SV=1 5.98 2151.4 - 1.48E+07 - - - 1.1476 - 1.35 0.113 - 68.8 1 2 0 0.0014 10 0 0 0 1.03E+07 5.96E+08 - - - 0.6759 0.9998 221125_WJC_METTL3_EV_vs_WT_F04.09965.09965.2 0.00205 20-Nov K.QLIVANAGDSR.C sp|O15355|PPM1G_HUMAN 1 1142.6044 0.73 44649 9965 2 1142.604208 572.3095 Protein phosphatase 1G OS=Homo sapiens OX=9606 GN=PPM1G PE=1 SV=1 5.84 2151.5 - 707810 - - - -0.1558 - 2.244 0.349 - 531.7 1 2 0 -0.0002 11 0 0 0 2.98E+07 4.10E+07 - - - 3.8052 0.9991 221125_WJC_METTL3_EV_vs_WT_F04.09967.09967.2 0.00671 22-Oct K.GAGEMLEDGSER[166.11].F sp|Q96DE5|APC16_HUMAN 1 1259.5328 3.38 44651 9967 2 1259.530302 630.7737 Anaphase-promoting complex subunit 16 OS=Homo sapiens OX=9606 GN=ANAPC16 PE=1 SV=1 4 2151.7 - 1.64E+06 - - - -1.9436 - 1.615 0.392 - 220.1 1 2 0 -0.0024 12 0 0 0 2.31E+07 6.82E+06 - - - 3.1968 0.9999 221125_WJC_METTL3_EV_vs_WT_F04.09968.09968.2 5.27E-06 22-Dec R.VAEELALEQAKK.E "sp|Q9NX63|MIC19_HUMAN,tr|A0A286YEX5|A0A286YEX5_HUMAN,tr|F8WAR4|F8WAR4_HUMAN,tr|C9JRZ6|C9JRZ6_HUMAN" 4 1327.7347 1.95 44652 9968 2 1327.73552 664.8746 MICOS complex subunit MIC19 OS=Homo sapiens OX=9606 GN=CHCHD3 PE=1 SV=1 4.79 2151.9 - 321688 - - - 0.5942 - 2.818 0.519 - 674.3 1 2 0 0.0008 12 0 0 0 5.96E+06 3.05E+06 - - - 5.6001 1 221125_WJC_METTL3_EV_vs_WT_F04.09971.09971.3 6.85E-07 19/40 K.TPVEPEVAIHR[166.11].L "sp|P60866|RS20_HUMAN,tr|E5RJX2|E5RJX2_HUMAN,tr|E5RIP1|E5RIP1_HUMAN,tr|A0A7P0S5H5|A0A7P0S5H5_HUMAN" 4 1256.6753 1.36 44653 9971 3 1256.674315 419.899 40S ribosomal protein S20 OS=Homo sapiens OX=9606 GN=RPS20 PE=1 SV=1 5.37 2152.3 - 662150 - - - -0.7488 - 3.013 0.462 - 771.6 1 2 0 -0.0009 11 0 0 0 2.06E+09 1.52E+09 - - - 6.8238 0.9977 221125_WJC_METTL3_EV_vs_WT_F04.09973.09973.2 0.0596 12-Jul K.TSWTPPR.Y "sp|Q9UJV9|DDX41_HUMAN,tr|A0A499FJW5|A0A499FJW5_HUMAN,tr|H0YA06|H0YA06_HUMAN,tr|D6RGI7|D6RGI7_HUMAN" 4 843.4239 0.8 44655 9973 2 843.423201 422.7192 Probable ATP-dependent RNA helicase DDX41 OS=Homo sapiens OX=9606 GN=DDX41 PE=1 SV=2 9.41 2152.5 - 902712 - - - -0.8311 - 1.267 0.27 - 292.2 1 2 0 -0.0007 7 0 0 0 5.84E+07 7.32E+07 - - - 1.7848 0.9992 221125_WJC_METTL3_EV_vs_WT_F04.09974.09974.2 0.0145 14-Jul R.EAILAIHK[136.11].E "sp|O43707|ACTN4_HUMAN,tr|F5GXS2|F5GXS2_HUMAN,tr|H7C144|H7C144_HUMAN" 3 901.5477 1.97 44656 9974 2 901.547208 451.7811 Alpha-actinin-4 OS=Homo sapiens OX=9606 GN=ACTN4 PE=1 SV=2 6.85 2152.6 - 744468 - - - -0.4925 - 1.545 0.298 - 143.6 1 2 0 -0.0004 8 0 0 0 2.09E+07 1.07E+07 - - - 2.5539 1 221125_WJC_METTL3_EV_vs_WT_F04.09975.09975.2 9.22E-07 13/24 A.FGNSTGGFDGQAR.Q sp|Q96PK6|RBM14_HUMAN 1 1312.5796 2.49 44657 9975 2 1312.57933 657.2971 RNA-binding protein 14 OS=Homo sapiens OX=9606 GN=RBM14 PE=1 SV=2 5.84 2152.7 - 487760 - - - -0.2263 - 2.524 0.635 - 496 1 1 0 -0.0003 13 0 0 0 8.84E+06 3.55E+06 - - - 6.1072 0.9832 221125_WJC_METTL3_EV_vs_WT_F04.09976.09976.2 0.00409 24-Jul A.FGNSTGGFDGQAR[166.11].Q sp|Q96PK6|RBM14_HUMAN 1 1322.5879 2.49 44658 9976 2 1322.587631 662.3012 RNA-binding protein 14 OS=Homo sapiens OX=9606 GN=RBM14 PE=1 SV=2 5.84 2152.8 - 267359 - - - -0.2011 - 1.679 0.442 - 108.2 1 1 0 -0.0003 13 0 0 0 8.84E+06 3.55E+06 - - - 3.6355 0.9999 221125_WJC_METTL3_EV_vs_WT_F04.09981.09981.2 0.00064 14/16 R.HVLVTLGEK.M "sp|P60660|MYL6_HUMAN,tr|F8W1R7|F8W1R7_HUMAN,tr|G3V1V0|G3V1V0_HUMAN,tr|B7Z6Z4|B7Z6Z4_HUMAN,tr|F8VZU9|F8VZU9_HUMAN,tr|G8JLA2|G8JLA2_HUMAN,tr|H0YI43|H0YI43_HUMAN,tr|F8W180|F8W180_HUMAN,tr|F8VXL3|F8VXL3_HUMAN,tr|G3V1Y7|G3V1Y7_HUMAN,tr|J3KND3|J3KND3_HUMAN,tr|F8VPF3|F8VPF3_HUMAN" 12 994.5811 1.24 44661 9981 2 994.580777 498.2978 Myosin light polypeptide 6 OS=Homo sapiens OX=9606 GN=MYL6 PE=1 SV=2 6.75 2153.4 - 1.32E+07 - - - -0.3559 - 2.478 0.484 - 705.9 1 2 0 -0.0004 9 0 0 0 6.30E+08 5.06E+08 - - - 5.241 0.9984 221125_WJC_METTL3_EV_vs_WT_F04.09982.09982.2 0.00531 14-Jul R.EFIQEPAK.N "sp|O14744|ANM5_HUMAN,tr|C9JSX3|C9JSX3_HUMAN,tr|G3V580|G3V580_HUMAN,tr|G3V2L6|G3V2L6_HUMAN,tr|G3V5L5|G3V5L5_HUMAN" 5 960.4916 3.01 44662 9982 2 960.48996 481.2531 Protein arginine N-methyltransferase 5 OS=Homo sapiens OX=9606 GN=PRMT5 PE=1 SV=4 4.53 2153.5 - 1.43E+06 - - - -1.7564 - 1.286 0.361 - 172.7 1 2 0 -0.0017 8 0 0 0 1.69E+08 5.61E+07 - - - 2.4654 1 221125_WJC_METTL3_EV_vs_WT_F04.09983.09983.3 2.33E-07 17/40 K.TPVEPEVAIHR.L "sp|P60866|RS20_HUMAN,tr|E5RJX2|E5RJX2_HUMAN,tr|E5RIP1|E5RIP1_HUMAN,tr|A0A7P0S5H5|A0A7P0S5H5_HUMAN" 4 1246.667 1.35 44663 9983 3 1246.66593 416.5629 40S ribosomal protein S20 OS=Homo sapiens OX=9606 GN=RPS20 PE=1 SV=1 5.37 2153.6 - 1.81E+06 - - - -0.8471 - 3.518 0.435 - 787.3 1 2 0 -0.0011 11 0 0 0 2.05E+09 1.51E+09 - - - 6.963 0.9957 221125_WJC_METTL3_EV_vs_WT_F04.09988.09988.3 0.0274 Sep-44 R.LDPHGGGLLSSK.A "sp|Q6KC79|NIPBL_HUMAN,tr|A0A590UJS4|A0A590UJS4_HUMAN" 2 1179.6248 1.15 44666 9988 3 1179.624055 394.2155 Nipped-B-like protein OS=Homo sapiens OX=9606 GN=NIPBL PE=1 SV=2 6.74 2154.2 - 420030 - - - -0.6205 - 1.791 0.195 - 71.9 1 2 0 -0.0007 12 0 0 0 1.40E+07 1.22E+07 - - - 2.3292 0.9596 221125_WJC_METTL3_EV_vs_WT_F04.09989.09989.2 0.00389 18-Jul R.SPPEALVQGR.Y "sp|Q9UHB6|LIMA1_HUMAN,tr|F8VRN8|F8VRN8_HUMAN" 2 1052.5615 1.28 44667 9989 2 1052.55664 527.288 LIM domain and actin-binding protein 1 OS=Homo sapiens OX=9606 GN=LIMA1 PE=1 SV=1 5.72 2154.4 - 411784 - - - -4.5774 - 1.522 0.173 - 184 1 2 0 -0.0048 10 0 0 0 1.04E+07 8.14E+06 - - - 1.4897 0.9998 221125_WJC_METTL3_EV_vs_WT_F04.09993.09993.2 9.76E-05 28-Oct R.FSTVAGESGSADTVR.D sp|P04040|CATA_HUMAN 1 1482.6951 999 44671 9993 2 1482.69614 742.3548 Catalase OS=Homo sapiens OX=9606 GN=CAT PE=1 SV=3 4.37 2154.8 - 163552 - - - 0.7345 - 1.882 0.504 - 270.6 1 2 0 0.0011 15 0 0 0 3.11E+07 0.00E+00 - - - 4.3178 0.9989 221125_WJC_METTL3_EV_vs_WT_F04.09995.09995.3 0.00467 Oct-36 R.TLK[136.11]PEGNILR[166.11].D "sp|Q9NZM5|NOP53_HUMAN,tr|M0QZ34|M0QZ34_HUMAN,tr|M0QYZ9|M0QYZ9_HUMAN,tr|M0QZU5|M0QZU5_HUMAN" 4 1157.6887 2.1 44672 9995 3 1157.687913 386.9035 Ribosome biogenesis protein NOP53 OS=Homo sapiens OX=9606 GN=NOP53 PE=1 SV=2 8.41 2155 - 831002 - - - -0.704 - 1.988 0.239 - 154 1 2 0 -0.0008 10 0 0 0 2.80E+07 1.33E+07 - - - 3.2111 0.9991 221125_WJC_METTL3_EV_vs_WT_F04.09997.09997.2 0.0745 18-Oct K.AGITTTLNSR.C "sp|P33992|MCM5_HUMAN,tr|B1AHB1|B1AHB1_HUMAN" 2 1032.5564 0.75 44673 9997 2 1032.555255 517.2855 DNA replication licensing factor MCM5 OS=Homo sapiens OX=9606 GN=MCM5 PE=1 SV=5 9.79 2155.2 - 1.78E+06 - - - -1.0827 - 1.972 0.238 - 256 1 2 0 -0.0011 10 0 0 0 4.81E+07 6.44E+07 - - - 2.6939 0.9996 221125_WJC_METTL3_EV_vs_WT_F04.09998.09998.2 0.000203 26-Dec K.GPGAGEGPGGAFAR[166.11].V "sp|Q9NQA3|WASH6_HUMAN,sp|C4AMC7|WASH3_HUMAN,sp|Q6VEQ5|WASH2_HUMAN,tr|A0A7I2YQU6|A0A7I2YQU6_HUMAN" 4 1209.5766 2.26 44674 9998 2 1209.577551 605.7956 WAS protein family homolog 6 OS=Homo sapiens OX=9606 GN=WASH6P PE=1 SV=3 6 2155.3 - 1.05E+06 - - - 0.7829 - 2.368 0.323 - 539.3 1 2 0 0.0009 14 0 0 0 1.12E+08 4.95E+07 - - - 3.5896 0.9987 221125_WJC_METTL3_EV_vs_WT_F04.10000.10000.2 0.0501 14-Aug R.DC[160.03]LINAAK.T "sp|P17987|TCPA_HUMAN,tr|F5H136|F5H136_HUMAN,tr|F5H7Y1|F5H7Y1_HUMAN,tr|E7ERF2|E7ERF2_HUMAN" 4 903.4484 0.51 44676 10000 2 903.447029 452.7315 T-complex protein 1 subunit alpha OS=Homo sapiens OX=9606 GN=TCP1 PE=1 SV=1 5.83 2155.5 - 1.07E+06 - - - -1.5197 - 1.504 0.307 - 220.3 1 2 0 -0.0014 8 0 0 0 1.08E+08 2.12E+08 - - - 2.539 0.9999 221125_WJC_METTL3_EV_vs_WT_F04.10001.10001.2 0.00101 24-Dec K.AVLEQEETAAASR[166.11].E "sp|Q9Y2J2|E41L3_HUMAN,tr|A0A0A0MRA8|A0A0A0MRA8_HUMAN,tr|A8K968|A8K968_HUMAN,tr|A0A0J9YY18|A0A0J9YY18_HUMAN,tr|A0A0A0MSA4|A0A0A0MSA4_HUMAN" 5 1383.6869 0.18 44677 10001 2 1383.686541 692.8507 Band 4.1-like protein 3 OS=Homo sapiens OX=9606 GN=EPB41L3 PE=1 SV=2 4.25 2155.6 - 639537 - - - -0.2905 - 2.728 0.548 - 538.4 1 2 0 -0.0004 13 0 0 0 1.15E+06 6.58E+06 - - - 5.6641 1 221125_WJC_METTL3_EV_vs_WT_F04.10004.10004.2 6.89E-08 24-Dec H.IVTC[160.03]ETNTGEVYR[166.11].G "sp|P62318|SMD3_HUMAN,tr|H3BT13|H3BT13_HUMAN" 2 1550.7274 1.53 44680 10004 2 1550.72509 776.371 Small nuclear ribonucleoprotein Sm D3 OS=Homo sapiens OX=9606 GN=SNRPD3 PE=1 SV=1 4.53 2156 - 191221 - - - -1.5077 - 2.626 0.632 - 570 1 1 0 -0.0023 13 0 0 0 1.19E+07 7.75E+06 - - - 6.1861 0.9998 221125_WJC_METTL3_EV_vs_WT_F04.10006.10006.2 0.00281 18-Sep R.GLDNTEFQGK[136.11].R "sp|Q9BWF3|RBM4_HUMAN,sp|Q9BQ04|RBM4B_HUMAN,tr|E9PB51|E9PB51_HUMAN" 3 1115.5339 1.51 44681 10006 2 1115.533777 558.7742 RNA-binding protein 4 OS=Homo sapiens OX=9606 GN=RBM4 PE=1 SV=1 4.37 2156.2 - 3.70E+07 - - - -0.0681 - 1.887 0.444 - 194.9 1 2 0 -0.0001 10 0 0 0 2.35E+09 1.56E+09 - - - 4.0928 0.9987 221125_WJC_METTL3_EV_vs_WT_F04.10007.10007.2 0.0105 16-Aug R.IQLNNPTER[166.11].V sp|Q8IYS2|K2013_HUMAN 1 1093.5755 2.92 44682 10007 2 1093.572996 547.795 Uncharacterized protein KIAA2013 OS=Homo sapiens OX=9606 GN=KIAA2013 PE=1 SV=1 6 2156.3 - 1.44E+06 - - - -2.3281 - 1.806 0.312 - 173 1 2 0 -0.0025 9 0 0 0 1.11E+08 3.81E+07 - - - 3.0548 0.9999 221125_WJC_METTL3_EV_vs_WT_F04.10008.10008.2 0.548 14/16 R.HVLVTLGEK[136.11].M "sp|P60660|MYL6_HUMAN,tr|F8W1R7|F8W1R7_HUMAN,tr|G3V1V0|G3V1V0_HUMAN,tr|B7Z6Z4|B7Z6Z4_HUMAN,tr|F8VZU9|F8VZU9_HUMAN,tr|G8JLA2|G8JLA2_HUMAN,tr|H0YI43|H0YI43_HUMAN,tr|F8W180|F8W180_HUMAN,tr|F8VXL3|F8VXL3_HUMAN,tr|G3V1Y7|G3V1Y7_HUMAN,tr|J3KND3|J3KND3_HUMAN,tr|F8VPF3|F8VPF3_HUMAN" 12 1002.5953 1.25 44683 10008 2 1002.594862 502.3049 Myosin light polypeptide 6 OS=Homo sapiens OX=9606 GN=MYL6 PE=1 SV=2 6.75 2156.3 - 2.41E+07 - - - -0.4678 - 2.563 0.499 - 730.6 1 2 0 -0.0005 9 0 0 0 6.29E+08 5.04E+08 - - - 5.4493 0.9998 221125_WJC_METTL3_EV_vs_WT_F04.10011.10011.2 6.42E-05 20-Nov K.TPVEPEVAIHR[166.11].L "sp|P60866|RS20_HUMAN,tr|E5RJX2|E5RJX2_HUMAN,tr|E5RIP1|E5RIP1_HUMAN,tr|A0A7P0S5H5|A0A7P0S5H5_HUMAN" 4 1256.6753 1.39 44686 10011 2 1256.67449 629.3449 40S ribosomal protein S20 OS=Homo sapiens OX=9606 GN=RPS20 PE=1 SV=1 5.37 2156.7 - 501277 - - - -0.6095 - 2.492 0.404 - 431.6 1 2 0 -0.0008 11 0 0 0 1.62E+08 1.16E+08 - - - 4.4948 0.9997 221125_WJC_METTL3_EV_vs_WT_F04.10015.10015.2 8.24E-05 18-Aug R.NVPYGNIQSR[166.11].L sp|Q10471|GALT2_HUMAN 1 1156.5864 1.46 44688 10015 2 1156.586127 579.3005 Polypeptide N-acetylgalactosaminyltransferase 2 OS=Homo sapiens OX=9606 GN=GALNT2 PE=1 SV=1 8.75 2157.2 - 3.37E+06 - - - -0.2715 - 1.49 0.457 - 208.8 1 2 0 -0.0003 10 0 0 0 2.72E+08 1.86E+08 - - - 3.5294 0.9998 221125_WJC_METTL3_EV_vs_WT_F04.10016.10016.2 9.21E-05 24-Dec R.SAPGAASAAAALK.Q sp|Q9H7S9|ZN703_HUMAN 1 1084.5877 1.57 44689 10016 2 1084.58742 543.3011 Zinc finger protein 703 OS=Homo sapiens OX=9606 GN=ZNF703 PE=1 SV=1 8.47 2157.2 - 2.99E+06 - - - -0.2333 - 2.011 0.43 - 341 1 2 0 -0.0003 13 0 0 0 1.95E+09 1.24E+09 - - - 4.01 0.9995 221125_WJC_METTL3_EV_vs_WT_F04.10017.10017.2 0.00546 18-Aug K.AAPPQIPDTR[166.11].R sp|Q9HAF1|EAF6_HUMAN 1 1074.5697 0.33 44690 10017 2 1074.570607 538.2921 Chromatin modification-related protein MEAF6 OS=Homo sapiens OX=9606 GN=MEAF6 PE=1 SV=1 5.88 2157.3 - 1.06E+06 - - - 0.818 - 1.559 0.393 - 201.5 1 2 0 0.0009 10 0 0 0 6.56E+07 2.00E+08 - - - 3.1829 1 221125_WJC_METTL3_EV_vs_WT_F04.10019.10019.2 1.56E-09 24-Dec H.IVTC[160.03]ETNTGEVYR.G "sp|P62318|SMD3_HUMAN,tr|H3BT13|H3BT13_HUMAN" 2 1540.7192 1.53 44692 10019 2 1540.718549 771.3669 Small nuclear ribonucleoprotein Sm D3 OS=Homo sapiens OX=9606 GN=SNRPD3 PE=1 SV=1 4.53 2157.6 - 478706 - - - -0.3953 - 2.436 0.667 - 539.8 1 1 0 -0.0006 13 0 0 0 1.19E+07 7.75E+06 - - - 6.2524 0.9955 221125_WJC_METTL3_EV_vs_WT_F04.10021.10021.2 0.11 18-Aug K.VIDQQNGLYR[166.11].C sp|P27694|RFA1_HUMAN 1 1214.6283 1.37 44694 10021 2 1214.625941 608.3214 Replication protein A 70 kDa DNA-binding subunit OS=Homo sapiens OX=9606 GN=RPA1 PE=1 SV=2 5.81 2157.8 - 176259 - - - -1.9471 - 1.234 0.284 - 159.3 1 2 0 -0.0024 10 0 0 0 1.49E+07 1.08E+07 - - - 1.7248 0.9995 221125_WJC_METTL3_EV_vs_WT_F04.10023.10023.2 0.00106 22-Dec R.LLQAVENGDAEK.V "sp|Q9P0K7|RAI14_HUMAN,tr|D6RB25|D6RB25_HUMAN,tr|D6RF74|D6RF74_HUMAN,tr|D6R9G6|D6R9G6_HUMAN,tr|D6RBY4|D6RBY4_HUMAN,tr|D6R9G4|D6R9G4_HUMAN,tr|D6RBW6|D6RBW6_HUMAN,tr|D6REL2|D6REL2_HUMAN,tr|D6RB27|D6RB27_HUMAN,tr|D6RE17|D6RE17_HUMAN" 10 1285.6514 1.92 44695 10023 2 1285.648294 643.833 Ankycorbin OS=Homo sapiens OX=9606 GN=RAI14 PE=1 SV=2 4.14 2158.1 - 460356 - - - -2.412 - 2.463 0.387 - 520.3 1 2 0 -0.0031 12 0 0 0 6.70E+06 3.49E+06 - - - 4.2701 0.9929 221125_WJC_METTL3_EV_vs_WT_F04.10025.10025.2 0.000612 16-Aug R.AQSLLSTDR.E "sp|O00231|PSD11_HUMAN,tr|J3QRY4|J3QRY4_HUMAN" 2 989.5142 0.13 44696 10025 2 989.517961 495.7644 26S proteasome non-ATPase regulatory subunit 11 OS=Homo sapiens OX=9606 GN=PSMD11 PE=1 SV=3 5.88 2158.3 - 2.18E+06 - - - 3.8271 - 1.696 0.264 - 259.6 1 2 0 0.0038 9 0 0 0 4.06E+07 3.16E+08 - - - 2.518 0.9999 221125_WJC_METTL3_EV_vs_WT_F04.10026.10026.2 9.49E-05 13/20 K.TPVEPEVAIHR.L "sp|P60866|RS20_HUMAN,tr|E5RJX2|E5RJX2_HUMAN,tr|E5RIP1|E5RIP1_HUMAN,tr|A0A7P0S5H5|A0A7P0S5H5_HUMAN" 4 1246.667 1.39 44697 10026 2 1246.667286 624.3408 40S ribosomal protein S20 OS=Homo sapiens OX=9606 GN=RPS20 PE=1 SV=1 5.37 2158.3 - 2.57E+06 - - - 0.2406 - 2.609 0.503 - 624.4 1 2 0 0.0003 11 0 0 0 1.62E+08 1.16E+08 - - - 5.3503 0.9933 221125_WJC_METTL3_EV_vs_WT_F04.10028.10028.2 1.87E-05 16/24 R.LQAALDDEEAGGR[166.11].P "sp|Q00839|HNRPU_HUMAN,tr|A0A1W2PPS1|A0A1W2PPS1_HUMAN,tr|A0A1X7SBS1|A0A1X7SBS1_HUMAN" 3 1353.64 1.14 44699 10028 2 1353.640681 677.8273 Heterogeneous nuclear ribonucleoprotein U OS=Homo sapiens OX=9606 GN=HNRNPU PE=1 SV=6 3.92 2158.5 - 672862 - - - 0.5083 - 2.8 0.472 - 1172.7 1 1 0 0.0007 13 0 0 0 4.26E+07 3.74E+07 - - - 5.1695 0.9982 221125_WJC_METTL3_EV_vs_WT_F04.10031.10031.2 0.00053 16-Aug K.SETDTSLIR[166.11].G sp|P40227|TCPZ_HUMAN 1 1030.517 0.5 44700 10031 2 1030.515481 516.2658 T-complex protein 1 subunit zeta OS=Homo sapiens OX=9606 GN=CCT6A PE=1 SV=3 4.37 2158.9 - 3.53E+06 - - - -1.4973 - 1.728 0.222 - 277.8 1 2 0 -0.0015 9 0 0 0 3.23E+08 6.46E+08 - - - 2.2626 0.9977 221125_WJC_METTL3_EV_vs_WT_F04.10033.10033.2 0.0364 22-Dec R.IQNAGGSVMIQR[166.11].V "sp|O75688|PPM1B_HUMAN,sp|P35813|PPM1A_HUMAN,tr|B8ZZF0|B8ZZF0_HUMAN,tr|A0A3B3IS24|A0A3B3IS24_HUMAN,tr|C9JIR6|C9JIR6_HUMAN,tr|E9PKB5|E9PKB5_HUMAN" 6 1282.6691 2.97 44702 10033 2 1282.673585 642.3418 Protein phosphatase 1B OS=Homo sapiens OX=9606 GN=PPM1B PE=1 SV=1 9.75 2159.1 - 611582 - - - 3.4771 - 2.402 0.276 - 645.1 1 2 0 0.0045 12 0 0 0 1.94E+09 6.53E+08 - - - 3.3838 0.9997 221125_WJC_METTL3_EV_vs_WT_F04.10036.10036.2 0.000374 18-Sep R.DLEGSDIDTR[166.11].R sp|P55060|XPO2_HUMAN 1 1129.5127 1.05 44703 10036 2 1129.511708 565.7636 Exportin-2 OS=Homo sapiens OX=9606 GN=CSE1L PE=1 SV=3 3.84 2159.5 - 2.68E+06 - - - -0.849 - 1.741 0.452 - 253.7 1 2 0 -0.001 10 0 0 0 1.13E+08 1.07E+08 - - - 3.9268 0.9996 221125_WJC_METTL3_EV_vs_WT_F04.10037.10037.2 2.95E-05 22-Nov R.IQNAGGSVMIQR.V "sp|O75688|PPM1B_HUMAN,sp|P35813|PPM1A_HUMAN,tr|B8ZZF0|B8ZZF0_HUMAN,tr|A0A3B3IS24|A0A3B3IS24_HUMAN,tr|C9JIR6|C9JIR6_HUMAN,tr|E9PKB5|E9PKB5_HUMAN" 6 1272.6609 2.97 44704 10037 2 1272.660307 637.3377 Protein phosphatase 1B OS=Homo sapiens OX=9606 GN=PPM1B PE=1 SV=1 9.75 2159.7 - 1.36E+06 - - - -0.4306 - 2.376 0.255 - 437.9 1 2 0 -0.0005 12 0 0 0 1.94E+09 6.52E+08 - - - 3.2013 0.9948 221125_WJC_METTL3_EV_vs_WT_F04.10039.10039.2 0.0893 14-Jul K.NWNSSVPR.S sp|O75319|DUS11_HUMAN 1 958.4621 1.3 44706 10039 2 958.462422 480.2383 RNA\RNP complex-1-interacting phosphatase OS=Homo sapiens OX=9606 GN=DUSP11 PE=1 SV=2 9.75 2159.9 - 913186 - - - 0.3589 - 1.148 0.223 - 204.4 1 2 0 0.0003 8 0 0 0 4.75E+07 3.66E+07 - - - 1.1042 1 221125_WJC_METTL3_EV_vs_WT_F04.10040.10040.2 0.000307 18/20 A.PGAASAAAALK.Q sp|Q9H7S9|ZN703_HUMAN 1 926.5185 1.71 44707 10040 2 926.519336 464.2665 Zinc finger protein 703 OS=Homo sapiens OX=9606 GN=ZNF703 PE=1 SV=1 9.18 2160 - 872832 - - - 0.8688 - 3.854 0.486 - 947.2 1 1 0 0.0008 11 0 0 0 8.90E+07 5.19E+07 - - - 6.28 0.9875 221125_WJC_METTL3_EV_vs_WT_F04.10041.10041.2 3.62 14-Jul K.GVLEGFK[136.11]K[136.11].N "sp|O75410|TACC1_HUMAN,tr|E7EVI4|E7EVI4_HUMAN,tr|B4E3H6|B4E3H6_HUMAN,tr|H0YAY0|H0YAY0_HUMAN,tr|H0YBT8|H0YBT8_HUMAN,tr|E7ET87|E7ET87_HUMAN" 6 892.5353 1.17 44708 10041 2 892.534675 447.2749 Transforming acidic coiled-coil-containing protein 1 OS=Homo sapiens OX=9606 GN=TACC1 PE=1 SV=2 8.59 2160.2 - 675808 - - - -0.7036 - 1.216 0.12 - 101.7 1 2 0 -0.0006 8 0 0 0 2.61E+07 2.23E+07 - - - 0.5169 0.9979 221125_WJC_METTL3_EV_vs_WT_F04.10042.10042.2 0.158 24-Aug R.VYIASSSGSTAIK[136.11].K sp|O75368|SH3L1_HUMAN 1 1290.6911 22.96 44709 10042 2 1290.689347 646.3528 SH3 domain-binding glutamic acid-rich-like protein OS=Homo sapiens OX=9606 GN=SH3BGRL PE=1 SV=1 8.56 2160.3 - 306629 - - - -1.3442 - 1.563 0.25 - 148.1 1 2 0 -0.0017 13 0 0 0 6.51E+07 2.84E+06 - - - 2.0332 0.9572 221125_WJC_METTL3_EV_vs_WT_F04.10045.10045.2 7.90E-05 16-Aug K.SETDTSLIR.G sp|P40227|TCPZ_HUMAN 1 1020.5088 0.48 44710 10045 2 1020.504013 511.2617 T-complex protein 1 subunit zeta OS=Homo sapiens OX=9606 GN=CCT6A PE=1 SV=3 4.37 2160.7 - 3.82E+06 - - - -4.6457 - 1.681 0.127 - 303.7 1 2 0 -0.0047 9 0 0 0 3.12E+08 6.45E+08 - - - 1.4802 0.9997 221125_WJC_METTL3_EV_vs_WT_F04.10046.10046.2 0.000155 26-Dec K.GPGAGEGPGGAFAR.V "sp|Q9NQA3|WASH6_HUMAN,sp|C4AMC7|WASH3_HUMAN,sp|Q6VEQ5|WASH2_HUMAN,tr|A0A7I2YQU6|A0A7I2YQU6_HUMAN" 4 1199.5683 2.68 44711 10046 2 1199.565971 600.7914 WAS protein family homolog 6 OS=Homo sapiens OX=9606 GN=WASH6P PE=1 SV=3 6 2160.8 - 2.14E+06 - - - -1.9699 - 2.306 0.441 - 239 1 2 0 -0.0024 14 0 0 0 1.33E+08 4.95E+07 - - - 4.3942 0.9788 221125_WJC_METTL3_EV_vs_WT_F04.10047.10047.2 0.0786 14-Jul R.VMTVSFHK[136.11].Y "sp|O15379|HDAC3_HUMAN,sp|Q92769|HDAC2_HUMAN,sp|Q13547|HDAC1_HUMAN,tr|E7ESJ6|E7ESJ6_HUMAN,tr|Q5TEE2|Q5TEE2_HUMAN" 5 955.5041 2.13 44712 10047 2 955.500034 478.7593 Histone deacetylase 3 OS=Homo sapiens OX=9606 GN=HDAC3 PE=1 SV=2 8.73 2160.9 - 1.23E+06 - - - -4.2271 - 1.188 0.304 - 123.9 1 2 0 -0.004 8 0 0 0 5.41E+07 2.55E+07 - - - 1.8046 0.9991 221125_WJC_METTL3_EV_vs_WT_F04.10048.10048.2 2.13E-05 18-Sep K.SEMTPEELQK.R "sp|P62316|SMD2_HUMAN,tr|K7ERG4|K7ERG4_HUMAN" 2 1190.5489 1.44 44713 10048 2 1190.545154 596.2817 Small nuclear ribonucleoprotein Sm D2 OS=Homo sapiens OX=9606 GN=SNRPD2 PE=1 SV=1 4.25 2161 - 1.01E+06 - - - -3.1498 - 1.77 0.486 - 278.6 1 2 0 -0.0037 10 0 0 0 2.08E+08 1.44E+08 - - - 4.2232 0.9993 221125_WJC_METTL3_EV_vs_WT_F04.10052.10052.2 0.13 18-Sep R.GGGQIIPTAR.R "sp|Q15029|U5S1_HUMAN,sp|P13639|EF2_HUMAN,tr|K7EJ74|K7EJ74_HUMAN,tr|K7EP67|K7EP67_HUMAN" 4 968.5403 0.79 44715 10052 2 968.539196 485.2774 116 kDa U5 small nuclear ribonucleoprotein component OS=Homo sapiens OX=9606 GN=EFTUD2 PE=1 SV=1 9.75 2161.5 - 1.33E+07 - - - -1.1698 - 1.781 0.316 - 270.2 1 2 0 -0.0011 10 0 0 0 4.46E+08 5.66E+08 - - - 2.9857 1 221125_WJC_METTL3_EV_vs_WT_F04.10053.10053.2 2.23E-05 13/24 R.LQAALDDEEAGGR.P "sp|Q00839|HNRPU_HUMAN,tr|A0A1W2PPS1|A0A1W2PPS1_HUMAN,tr|A0A1X7SBS1|A0A1X7SBS1_HUMAN" 3 1343.6317 1.14 44716 10053 2 1343.630408 672.8231 Heterogeneous nuclear ribonucleoprotein U OS=Homo sapiens OX=9606 GN=HNRNPU PE=1 SV=6 3.92 2161.6 - 2.27E+06 - - - -0.9787 - 2.783 0.627 - 716.8 1 1 0 -0.0013 13 0 0 0 4.26E+07 3.74E+07 - - - 6.2985 0.9985 221125_WJC_METTL3_EV_vs_WT_F04.10055.10055.2 0.00693 14-Sep R.VMTVSFHK.Y "sp|O15379|HDAC3_HUMAN,sp|Q92769|HDAC2_HUMAN,sp|Q13547|HDAC1_HUMAN,tr|E7ESJ6|E7ESJ6_HUMAN,tr|Q5TEE2|Q5TEE2_HUMAN" 5 947.4899 2.5 44718 10055 2 947.488838 474.7522 Histone deacetylase 3 OS=Homo sapiens OX=9606 GN=HDAC3 PE=1 SV=2 8.73 2161.7 - 1.84E+06 - - - -1.0924 - 1.634 0.23 - 307.5 1 2 0 -0.001 8 0 0 0 6.69E+07 2.67E+07 - - - 2.2204 0.9995 221125_WJC_METTL3_EV_vs_WT_F04.10056.10056.2 0.00173 18-Aug K.ATISDEEIER.Q "sp|Q9UQN3|CHM2B_HUMAN,tr|C9J0A7|C9J0A7_HUMAN,tr|A0A087WW88|A0A087WW88_HUMAN" 3 1161.5513 1.25 44719 10056 2 1161.55005 581.7829 Charged multivesicular body protein 2b OS=Homo sapiens OX=9606 GN=CHMP2B PE=1 SV=1 4 2161.8 - 1.74E+06 - - - -1.1166 - 1.739 0.359 - 188 1 2 0 -0.0013 10 0 0 0 1.70E+07 1.36E+07 - - - 3.2366 0.8017 221125_WJC_METTL3_EV_vs_WT_F04.10058.10058.2 0.429 14-Sep L.LQVQHASK[136.11].Q "sp|P12235|ADT1_HUMAN,sp|P05141|ADT2_HUMAN,sp|P12236|ADT3_HUMAN,tr|V9GYG0|V9GYG0_HUMAN" 4 917.5174 0.67 44721 10058 2 917.517274 459.766 ADP\ATP translocase 1 OS=Homo sapiens OX=9606 GN=SLC25A4 PE=1 SV=4 8.76 2162 - 840751 - - - -0.1537 - 1.49 0.135 - 252.4 1 1 0 -0.0001 8 0 0 0 2.79E+07 4.17E+07 - - - 1.2408 0.9997 221125_WJC_METTL3_EV_vs_WT_F04.10059.10059.2 5.56E-05 22-Oct R.VVIQSNDDIASR.A sp|Q93008|USP9X_HUMAN 1 1315.6732 0.59 44722 10059 2 1315.674096 658.8439 Probable ubiquitin carboxyl-terminal hydrolase FAF-X OS=Homo sapiens OX=9606 GN=USP9X PE=1 SV=4 4.21 2162.2 - 397834 - - - 0.6863 - 1.906 0.409 - 355 1 2 0 0.0009 12 0 0 0 9.85E+06 1.67E+07 - - - 3.7587 0.9983 221125_WJC_METTL3_EV_vs_WT_F04.10062.10062.2 0.0201 18-Sep R.AQLGGPELQR.L sp|Q9HBH1|DEFM_HUMAN 1 1067.5724 0.45 44723 10062 2 1067.570966 534.7935 "Peptide deformylase, mitochondrial OS=Homo sapiens OX=9606 GN=PDF PE=1 SV=1" 6.05 2162.5 - 2.20E+06 - - - -1.303 - 1.826 0.197 - 329.4 1 2 0 -0.0014 10 0 0 0 1.31E+08 2.89E+08 - - - 2.1763 0.9994 221125_WJC_METTL3_EV_vs_WT_F04.10063.10063.2 40.3 18-Oct K.LLLQVQHASK.Q "sp|P12235|ADT1_HUMAN,sp|P05141|ADT2_HUMAN,sp|P12236|ADT3_HUMAN,tr|V9GYG0|V9GYG0_HUMAN" 4 1135.6713 0.82 44724 10063 2 1135.670092 568.8429 ADP\ATP translocase 1 OS=Homo sapiens OX=9606 GN=SLC25A4 PE=1 SV=4 8.76 2162.6 - 2.33E+06 - - - -1.1016 - 1.993 0.287 - 267.3 1 2 0 -0.0013 10 0 0 0 6.54E+07 7.95E+07 - - - 3.0854 0.9954 221125_WJC_METTL3_EV_vs_WT_F04.10064.10064.3 4.02E-05 17/36 T.PVEPEVAIHR[166.11].L "sp|P60866|RS20_HUMAN,tr|E5RJX2|E5RJX2_HUMAN,tr|E5RIP1|E5RIP1_HUMAN,tr|A0A7P0S5H5|A0A7P0S5H5_HUMAN" 4 1155.6276 1.24 44725 10064 3 1155.625467 386.2165 40S ribosomal protein S20 OS=Homo sapiens OX=9606 GN=RPS20 PE=1 SV=1 5.41 2162.7 - 1.09E+06 - - - -1.8258 - 2.845 0.45 - 659.2 1 1 0 -0.0021 10 0 0 0 2.94E+07 2.37E+07 - - - 6.61 0.9107 221125_WJC_METTL3_EV_vs_WT_F04.10065.10065.2 0.00352 18-Jul R.DNIQGITKPA.L sp|P62805|H4_HUMAN 1 1055.5611 1.5 44726 10065 2 1055.560346 528.7878 Histone H4 OS=Homo sapiens OX=9606 GN=H4C1 PE=1 SV=2 5.84 2162.8 - 929096 - - - -0.737 - 1.585 0.23 - 170.2 1 1 0 -0.0008 10 0 0 0 3.96E+07 2.64E+07 - - - 2.0252 0.9814 221125_WJC_METTL3_EV_vs_WT_F04.10068.10068.3 0.0368 Sep-44 R.IQNAGGSVMIQR.V "sp|O75688|PPM1B_HUMAN,sp|P35813|PPM1A_HUMAN,tr|B8ZZF0|B8ZZF0_HUMAN,tr|A0A3B3IS24|A0A3B3IS24_HUMAN,tr|C9JIR6|C9JIR6_HUMAN,tr|E9PKB5|E9PKB5_HUMAN" 6 1272.6609 2.93 44727 10068 3 1272.659416 425.2276 Protein phosphatase 1B OS=Homo sapiens OX=9606 GN=PPM1B PE=1 SV=1 9.75 2163.2 - 1.99E+06 - - - -1.1307 - 1.489 0.164 - 143.9 1 2 0 -0.0014 12 0 0 0 1.50E+08 5.13E+07 - - - 1.4715 0.9991 221125_WJC_METTL3_EV_vs_WT_F04.10070.10070.2 0.0474 18-Oct R.GGGQIIPTAR[166.11].R "sp|Q15029|U5S1_HUMAN,sp|P13639|EF2_HUMAN,tr|K7EJ74|K7EJ74_HUMAN,tr|K7EP67|K7EP67_HUMAN" 4 978.5486 0.8 44728 10070 2 978.547199 490.2816 116 kDa U5 small nuclear ribonucleoprotein component OS=Homo sapiens OX=9606 GN=EFTUD2 PE=1 SV=1 9.75 2163.4 - 1.91E+07 - - - -1.4307 - 1.82 0.289 - 397.6 1 2 0 -0.0014 10 0 0 0 4.44E+08 5.55E+08 - - - 2.8466 1 221125_WJC_METTL3_EV_vs_WT_F04.10071.10071.2 8.30E-07 17/20 A.PGAASAAAALK[136.11].Q sp|Q9H7S9|ZN703_HUMAN 1 934.5327 1.72 44729 10071 2 934.532224 468.2736 Zinc finger protein 703 OS=Homo sapiens OX=9606 GN=ZNF703 PE=1 SV=1 9.18 2163.5 - 2.26E+06 - - - -0.5425 - 3.628 0.477 - 672.5 1 1 0 -0.0005 11 0 0 0 8.88E+07 5.16E+07 - - - 6.0502 0.9998 221125_WJC_METTL3_EV_vs_WT_F04.10072.10072.2 0.00179 20-Dec K.LQQTYAALNSK.A "sp|P46940|IQGA1_HUMAN,tr|H0YLE8|H0YLE8_HUMAN" 2 1235.651 0.92 44730 10072 2 1235.649224 618.8328 Ras GTPase-activating-like protein IQGAP1 OS=Homo sapiens OX=9606 GN=IQGAP1 PE=1 SV=1 8.59 2163.6 - 1.66E+06 - - - -1.4381 - 2.365 0.427 - 511.3 1 2 0 -0.0018 11 0 0 0 4.23E+07 4.62E+07 - - - 4.5229 0.9561 221125_WJC_METTL3_EV_vs_WT_F04.10073.10073.2 0.0221 12-Aug L.PEHAVLK.M "sp|Q00839|HNRPU_HUMAN,tr|A0A1W2PQL0|A0A1W2PQL0_HUMAN,tr|A0A1W2PPL4|A0A1W2PPL4_HUMAN,tr|A0A1W2PQ74|A0A1W2PQ74_HUMAN,tr|Q5RI18|Q5RI18_HUMAN,tr|A0A1W2PP35|A0A1W2PP35_HUMAN,tr|A0A1W2PPS1|A0A1W2PPS1_HUMAN,tr|A0A1W2PRZ7|A0A1W2PRZ7_HUMAN,tr|A0A1W2PPH7|A0A1W2PPH7_HUMAN,tr|A0A1W2PQD4|A0A1W2PQD4_HUMAN,tr|A0A1W2PP34|A0A1W2PP34_HUMAN,tr|A0A1X7SBS1|A0A1X7SBS1_HUMAN" 12 792.4494 1.05 44731 10073 2 792.447537 397.232 Heterogeneous nuclear ribonucleoprotein U OS=Homo sapiens OX=9606 GN=HNRNPU PE=1 SV=6 7.17 2163.7 - 1.65E+06 - - - -2.3358 - 2.033 0.322 - 237 1 1 0 -0.0019 7 0 0 0 2.88E+09 2.74E+09 - - - 3.6668 0.9992 221125_WJC_METTL3_EV_vs_WT_F04.10074.10074.2 0.0126 14-Aug K.NQELEVVR.Q "sp|Q14203|DCTN1_HUMAN,tr|A0A804CDA6|A0A804CDA6_HUMAN,tr|E7EX90|E7EX90_HUMAN,tr|A0A7P0Z4C3|A0A7P0Z4C3_HUMAN,tr|Q6AWB1|Q6AWB1_HUMAN" 5 985.5193 2.45 44732 10074 2 985.518046 493.7669 Dynactin subunit 1 OS=Homo sapiens OX=9606 GN=DCTN1 PE=1 SV=3 4.53 2163.8 - 1.25E+06 - - - -1.2308 - 1.84 0.265 - 376.9 1 2 0 -0.0012 8 0 0 0 6.53E+07 2.66E+07 - - - 2.8369 0.9701 221125_WJC_METTL3_EV_vs_WT_F04.10075.10075.2 0.00188 14-Aug K.KDDAITAY.K "sp|Q9BY77|PDIP3_HUMAN,tr|F6VRR5|F6VRR5_HUMAN" 2 895.4287 0.22 44733 10075 2 895.428584 448.7216 Polymerase delta-interacting protein 3 OS=Homo sapiens OX=9606 GN=POLDIP3 PE=1 SV=2 4.21 2164 - 865016 - - - -0.1441 - 1.439 0.386 - 265.8 1 1 0 -0.0001 8 0 0 0 2.40E+07 1.10E+08 - - - 2.9896 0.9985 221125_WJC_METTL3_EV_vs_WT_F04.10076.10076.2 0.337 14-Aug K.KIFVGGIK.E "sp|Q32P51|RA1L2_HUMAN,sp|P51991|ROA3_HUMAN,sp|Q13151|ROA0_HUMAN,sp|P09651|ROA1_HUMAN,sp|P22626|ROA2_HUMAN,tr|A0A7I2YQN4|A0A7I2YQN4_HUMAN,tr|A0A7I2YQX9|A0A7I2YQX9_HUMAN,tr|A0A7I2V4N0|A0A7I2V4N0_HUMAN,tr|A0A024RA28|A0A024RA28_HUMAN,tr|A0A7I2V4N1|A0A7I2V4N1_HUMAN,tr|A0A7I2V5D8|A0A7I2V5D8_HUMAN,tr|A0A7I2V2R3|A0A7I2V2R3_HUMAN,tr|A0A7I2V4I6|A0A7I2V4I6_HUMAN,tr|F8VZ49|F8VZ49_HUMAN,tr|A0A7I2V3R8|A0A7I2V3R8_HUMAN,tr|A0A087WUI2|A0A087WUI2_HUMAN,tr|A0A7I2V4S4|A0A7I2V4S4_HUMAN,tr|F8VTQ5|F8VTQ5_HUMAN,tr|F8W6I7|F8W6I7_HUMAN,tr|A0A7I2V2L6|A0A7I2V2L6_HUMAN,tr|A0A7I2V4J6|A0A7I2V4J6_HUMAN,tr|A0A7I2V323|A0A7I2V323_HUMAN,tr|A0A7I2V3W0|A0A7I2V3W0_HUMAN,tr|A0A7I2V4G0|A0A7I2V4G0_HUMAN,tr|A0A7I2V5U9|A0A7I2V5U9_HUMAN,tr|A0A2R8Y4L2|A0A2R8Y4L2_HUMAN,tr|A0A7I2V402|A0A7I2V402_HUMAN,tr|A0A7I2V3P1|A0A7I2V3P1_HUMAN,tr|A0A7I2V3P7|A0A7I2V3P7_HUMAN" 29 860.5484 1.14 44734 10076 2 860.547342 431.2815 Heterogeneous nuclear ribonucleoprotein A1-like 2 OS=Homo sapiens OX=9606 GN=HNRNPA1L2 PE=2 SV=2 10 2164.1 - 745106 - - - -1.1992 - 1.846 0.188 - 272.2 1 2 0 -0.001 8 0 0 0 2.43E+07 2.12E+07 - - - 2.2781 0.9999 221125_WJC_METTL3_EV_vs_WT_F04.10078.10078.2 0.0191 14/26 R.GEGPGEAGGPLTPR.R sp|P50548|ERF_HUMAN 1 1293.6313 2.23 44736 10078 2 1293.631826 647.8229 ETS domain-containing transcription factor ERF OS=Homo sapiens OX=9606 GN=ERF PE=1 SV=2 4.53 2164.3 - 376042 - - - 0.3842 - 2.821 0.418 - 572.6 1 2 0 0.0005 14 0 0 0 2.39E+07 1.07E+07 - - - 4.7307 0.9998 221125_WJC_METTL3_EV_vs_WT_F04.10081.10081.3 0.000164 Oct-36 K.LLLQVQHASK[136.11].Q "sp|P12235|ADT1_HUMAN,sp|P05141|ADT2_HUMAN,sp|P12236|ADT3_HUMAN,tr|V9GYG0|V9GYG0_HUMAN" 4 1143.6855 0.03 44737 10081 3 1143.683264 382.2358 ADP\ATP translocase 1 OS=Homo sapiens OX=9606 GN=SLC25A4 PE=1 SV=4 8.76 2164.7 - 2.65E+07 - - - -1.9927 - 1.771 0.445 - 93.2 1 2 0 -0.0023 10 0 0 0 1.63E+07 4.87E+08 - - - 5.1698 0.9817 221125_WJC_METTL3_EV_vs_WT_F04.10083.10083.2 0.00331 12-Oct L.PEHAVLK[136.11].M "sp|Q00839|HNRPU_HUMAN,tr|A0A1W2PQL0|A0A1W2PQL0_HUMAN,tr|A0A1W2PPL4|A0A1W2PPL4_HUMAN,tr|A0A1W2PQ74|A0A1W2PQ74_HUMAN,tr|Q5RI18|Q5RI18_HUMAN,tr|A0A1W2PP35|A0A1W2PP35_HUMAN,tr|A0A1W2PPS1|A0A1W2PPS1_HUMAN,tr|A0A1W2PRZ7|A0A1W2PRZ7_HUMAN,tr|A0A1W2PPH7|A0A1W2PPH7_HUMAN,tr|A0A1W2PQD4|A0A1W2PQD4_HUMAN,tr|A0A1W2PP34|A0A1W2PP34_HUMAN,tr|A0A1X7SBS1|A0A1X7SBS1_HUMAN" 12 800.4636 1.05 44739 10083 2 800.462263 401.2391 Heterogeneous nuclear ribonucleoprotein U OS=Homo sapiens OX=9606 GN=HNRNPU PE=1 SV=6 7.17 2164.8 - 6.32E+06 - - - -1.6553 - 2.159 0.371 - 474.2 1 1 0 -0.0013 7 0 0 0 2.88E+09 2.74E+09 - - - 4.2195 0.9992 221125_WJC_METTL3_EV_vs_WT_F04.10085.10085.2 0.00335 14-Aug K.K[136.11]IFVGGIK[136.11].E "sp|Q32P51|RA1L2_HUMAN,sp|P51991|ROA3_HUMAN,sp|Q13151|ROA0_HUMAN,sp|P09651|ROA1_HUMAN,sp|P22626|ROA2_HUMAN,tr|A0A7I2YQN4|A0A7I2YQN4_HUMAN,tr|A0A7I2YQX9|A0A7I2YQX9_HUMAN,tr|A0A7I2V4N0|A0A7I2V4N0_HUMAN,tr|A0A024RA28|A0A024RA28_HUMAN,tr|A0A7I2V4N1|A0A7I2V4N1_HUMAN,tr|A0A7I2V5D8|A0A7I2V5D8_HUMAN,tr|A0A7I2V2R3|A0A7I2V2R3_HUMAN,tr|A0A7I2V4I6|A0A7I2V4I6_HUMAN,tr|F8VZ49|F8VZ49_HUMAN,tr|A0A7I2V3R8|A0A7I2V3R8_HUMAN,tr|A0A087WUI2|A0A087WUI2_HUMAN,tr|A0A7I2V4S4|A0A7I2V4S4_HUMAN,tr|F8VTQ5|F8VTQ5_HUMAN,tr|F8W6I7|F8W6I7_HUMAN,tr|A0A7I2V2L6|A0A7I2V2L6_HUMAN,tr|A0A7I2V4J6|A0A7I2V4J6_HUMAN,tr|A0A7I2V323|A0A7I2V323_HUMAN,tr|A0A7I2V3W0|A0A7I2V3W0_HUMAN,tr|A0A7I2V4G0|A0A7I2V4G0_HUMAN,tr|A0A7I2V5U9|A0A7I2V5U9_HUMAN,tr|A0A2R8Y4L2|A0A2R8Y4L2_HUMAN,tr|A0A7I2V402|A0A7I2V402_HUMAN,tr|A0A7I2V3P1|A0A7I2V3P1_HUMAN,tr|A0A7I2V3P7|A0A7I2V3P7_HUMAN" 29 876.5768 1.14 44741 10085 2 876.574669 439.2957 Heterogeneous nuclear ribonucleoprotein A1-like 2 OS=Homo sapiens OX=9606 GN=HNRNPA1L2 PE=2 SV=2 10 2165.1 - 1.19E+06 - - - -2.4014 - 1.962 0.346 - 279.3 1 2 0 -0.0021 8 0 0 0 2.43E+07 2.12E+07 - - - 3.6285 0.9997 221125_WJC_METTL3_EV_vs_WT_F04.10089.10089.2 7.94E-06 24-Dec R.SAPGAASAAAALK[136.11].Q sp|Q9H7S9|ZN703_HUMAN 1 1092.6019 1.57 44744 10089 2 1092.599818 547.3082 Zinc finger protein 703 OS=Homo sapiens OX=9606 GN=ZNF703 PE=1 SV=1 8.47 2165.5 - 4.70E+07 - - - -1.8808 - 1.946 0.488 - 425.9 1 2 0 -0.0021 13 0 0 0 1.94E+09 1.24E+09 - - - 4.3535 0.9991 221125_WJC_METTL3_EV_vs_WT_F04.10093.10093.3 0.0083 Dec-44 R.IQNAGGSVMIQR[166.11].V "sp|O75688|PPM1B_HUMAN,sp|P35813|PPM1A_HUMAN,tr|B8ZZF0|B8ZZF0_HUMAN,tr|A0A3B3IS24|A0A3B3IS24_HUMAN,tr|C9JIR6|C9JIR6_HUMAN,tr|E9PKB5|E9PKB5_HUMAN" 6 1282.6691 2.82 44747 10093 3 1282.667008 428.5637 Protein phosphatase 1B OS=Homo sapiens OX=9606 GN=PPM1B PE=1 SV=1 9.75 2165.9 - 2.75E+06 - - - -1.6505 - 1.932 0.291 - 210.1 1 2 0 -0.0021 12 0 0 0 1.44E+08 5.09E+07 - - - 3.6092 0.9174 221125_WJC_METTL3_EV_vs_WT_F04.10094.10094.2 1.18 18-Aug R.TSLGPNGLDK[136.11].M "sp|P48643|TCPE_HUMAN,tr|E9PCA1|E9PCA1_HUMAN,tr|B7ZAR1|B7ZAR1_HUMAN" 3 1008.5331 0.67 44748 10094 2 1008.529729 505.2738 T-complex protein 1 subunit epsilon OS=Homo sapiens OX=9606 GN=CCT5 PE=1 SV=1 5.5 2166.1 - 379281 - - - -3.3673 - 1.247 0.093 - 117.2 1 2 0 -0.0034 10 0 0 0 1.62E+09 2.40E+09 - - - 0.343 0.9998 221125_WJC_METTL3_EV_vs_WT_F04.10099.10099.2 0.00679 18-Nov R.ITELTDENVK[136.11].F "sp|P19387|RPB3_HUMAN,tr|H3BRR2|H3BRR2_HUMAN" 2 1168.6067 2.56 44751 10099 2 1168.604805 585.3106 DNA-directed RNA polymerase II subunit RPB3 OS=Homo sapiens OX=9606 GN=POLR2C PE=1 SV=2 4.14 2166.6 - 1.40E+06 - - - -1.6079 - 2.273 0.448 - 395.1 1 2 0 -0.0019 10 0 0 0 6.23E+07 2.44E+07 - - - 4.6413 0.9996 221125_WJC_METTL3_EV_vs_WT_F04.10104.10104.2 0.00634 20-Sep K.VATPMSVTSQR.F sp|Q9HBM6|TAF9B_HUMAN 1 1175.5969 0.94 44754 10104 2 1175.595561 588.8057 Transcription initiation factor TFIID subunit 9B OS=Homo sapiens OX=9606 GN=TAF9B PE=1 SV=1 9.72 2167.3 - 785360 - - - -1.1024 - 1.693 0.406 - 238 1 2 0 -0.0013 11 0 0 0 3.78E+07 4.02E+07 - - - 3.4636 0.9999 221125_WJC_METTL3_EV_vs_WT_F04.10105.10105.2 0.00097 16-Oct R.QQDLDGELR.S sp|Q99459|CDC5L_HUMAN 1 1072.5149 1.87 44755 10105 2 1072.514006 537.2647 Cell division cycle 5-like protein OS=Homo sapiens OX=9606 GN=CDC5L PE=1 SV=2 4.03 2167.3 - 7.48E+06 - - - -0.8354 - 2.259 0.483 - 620.3 1 2 0 -0.0009 9 0 0 0 1.60E+08 8.55E+07 - - - 4.9658 0.9995 221125_WJC_METTL3_EV_vs_WT_F04.10106.10106.2 0.0242 18-Oct K.LLLQVQHASK[136.11].Q "sp|P12235|ADT1_HUMAN,sp|P05141|ADT2_HUMAN,sp|P12236|ADT3_HUMAN,tr|V9GYG0|V9GYG0_HUMAN" 4 1143.6855 0.82 44756 10106 2 1143.683921 572.85 ADP\ATP translocase 1 OS=Homo sapiens OX=9606 GN=SLC25A4 PE=1 SV=4 8.76 2167.4 - 3.52E+06 - - - -1.4182 - 2.237 0.279 - 360.5 1 2 0 -0.0016 10 0 0 0 6.54E+07 7.95E+07 - - - 3.3486 0.9992 221125_WJC_METTL3_EV_vs_WT_F04.10108.10108.2 0.0055 20-Sep R.GTPDTDLEVQR.V sp|P0C7T5|ATX1L_HUMAN 1 1229.5888 7.34 44758 10108 2 1229.590967 615.8017 Ataxin-1-like OS=Homo sapiens OX=9606 GN=ATXN1L PE=1 SV=1 4.03 2167.6 - 537987 - - - 1.7664 - 1.733 0.361 - 261.7 1 2 0 0.0022 11 0 0 0 5.66E+07 7.72E+06 - - - 3.1941 0.9994 221125_WJC_METTL3_EV_vs_WT_F04.10116.10116.2 0.00698 20-Oct K.LQQTYAALNSK[136.11].A "sp|P46940|IQGA1_HUMAN,tr|H0YLE8|H0YLE8_HUMAN" 2 1243.6652 0.92 44763 10116 2 1243.663709 622.8399 Ras GTPase-activating-like protein IQGAP1 OS=Homo sapiens OX=9606 GN=IQGAP1 PE=1 SV=1 8.59 2168.5 - 1.10E+06 - - - -1.1997 - 1.924 0.315 - 300.7 1 2 0 -0.0015 11 0 0 0 4.23E+07 4.60E+07 - - - 3.1374 0.987 221125_WJC_METTL3_EV_vs_WT_F04.10118.10118.2 0.492 16-Aug K.DLPEHAVLK.M "sp|Q00839|HNRPU_HUMAN,tr|A0A1W2PQL0|A0A1W2PQL0_HUMAN,tr|A0A1W2PPL4|A0A1W2PPL4_HUMAN,tr|A0A1W2PQ74|A0A1W2PQ74_HUMAN,tr|Q5RI18|Q5RI18_HUMAN,tr|A0A1W2PP35|A0A1W2PP35_HUMAN,tr|A0A1W2PPS1|A0A1W2PPS1_HUMAN,tr|A0A1W2PRZ7|A0A1W2PRZ7_HUMAN,tr|A0A1W2PPH7|A0A1W2PPH7_HUMAN,tr|A0A1W2PQD4|A0A1W2PQD4_HUMAN,tr|A0A1W2PP34|A0A1W2PP34_HUMAN,tr|A0A1X7SBS1|A0A1X7SBS1_HUMAN" 12 1020.5604 1.11 44764 10118 2 1020.558395 511.2875 Heterogeneous nuclear ribonucleoprotein U OS=Homo sapiens OX=9606 GN=HNRNPU PE=1 SV=6 5.32 2168.7 - 5.67E+07 - - - -1.9597 - 1.394 0.128 - 145.8 1 2 0 -0.002 9 0 0 0 2.61E+09 2.35E+09 - - - 0.9468 1 221125_WJC_METTL3_EV_vs_WT_F04.10119.10119.3 0.00127 15/40 K.VADMALHYANK[136.11].Y "sp|P50990|TCPQ_HUMAN,tr|H7C4C8|H7C4C8_HUMAN" 2 1239.6161 0.34 44765 10119 3 1239.614711 414.2127 T-complex protein 1 subunit theta OS=Homo sapiens OX=9606 GN=CCT8 PE=1 SV=4 6.71 2168.8 - 1.96E+06 - - - -1.1552 - 2.865 0.468 - 453.1 1 2 0 -0.0014 11 0 0 0 2.15E+08 6.25E+08 - - - 6.7475 0.9994 221125_WJC_METTL3_EV_vs_WT_F04.10120.10120.2 0.00381 16-Aug K.FNEENYGVK[136.11].T "sp|Q8WWM7|ATX2L_HUMAN,tr|H3BSK9|H3BSK9_HUMAN,tr|H3BUF6|H3BUF6_HUMAN" 3 1106.5124 0.17 44766 10120 2 1106.509558 554.2635 Ataxin-2-like protein OS=Homo sapiens OX=9606 GN=ATXN2L PE=1 SV=2 4.53 2168.8 - 4.10E+06 - - - -2.5585 - 1.875 0.443 - 138.5 1 2 0 -0.0028 9 0 0 0 2.14E+08 1.24E+09 - - - 4.1307 0.7755 221125_WJC_METTL3_EV_vs_WT_F04.10121.10121.2 0.0436 14-Oct D.LPEHAVLK[136.11].M "sp|Q00839|HNRPU_HUMAN,tr|A0A1W2PQL0|A0A1W2PQL0_HUMAN,tr|A0A1W2PPL4|A0A1W2PPL4_HUMAN,tr|A0A1W2PQ74|A0A1W2PQ74_HUMAN,tr|Q5RI18|Q5RI18_HUMAN,tr|A0A1W2PP35|A0A1W2PP35_HUMAN,tr|A0A1W2PPS1|A0A1W2PPS1_HUMAN,tr|A0A1W2PRZ7|A0A1W2PRZ7_HUMAN,tr|A0A1W2PPH7|A0A1W2PPH7_HUMAN,tr|A0A1W2PQD4|A0A1W2PQD4_HUMAN,tr|A0A1W2PP34|A0A1W2PP34_HUMAN,tr|A0A1X7SBS1|A0A1X7SBS1_HUMAN" 12 913.5477 1.03 44767 10121 2 913.545758 457.7811 Heterogeneous nuclear ribonucleoprotein U OS=Homo sapiens OX=9606 GN=HNRNPU PE=1 SV=6 6.75 2168.9 - 1.30E+06 - - - -2.0732 - 1.708 0.148 - 333.8 1 1 0 -0.0019 8 0 0 0 4.10E+07 3.99E+07 - - - 1.748 0.9987 221125_WJC_METTL3_EV_vs_WT_F04.10122.10122.3 0.0256 Nov-40 K.VLEHQLLQTTK.L "sp|O14530|TXND9_HUMAN,tr|G3XAJ4|G3XAJ4_HUMAN,tr|F8WBV5|F8WBV5_HUMAN,tr|F8WCJ3|F8WCJ3_HUMAN,tr|B8ZZX4|B8ZZX4_HUMAN" 5 1308.7402 2.45 44768 10122 3 1308.739633 437.254 Thioredoxin domain-containing protein 9 OS=Homo sapiens OX=9606 GN=TXNDC9 PE=1 SV=2 6.72 2169 - 1.22E+06 - - - -0.3958 - 2.017 0.233 - 121.1 1 2 0 -0.0005 11 0 0 0 2.71E+07 1.10E+07 - - - 3.1307 0.998 221125_WJC_METTL3_EV_vs_WT_F04.10127.10127.3 0.000199 13/36 K.VVWVEESDK[136.11]R[166.11].S "sp|O00571|DDX3X_HUMAN,tr|A0A2R8YFR4|A0A2R8YFR4_HUMAN,tr|A0A2R8YCW1|A0A2R8YCW1_HUMAN,tr|A0A2R8YDH3|A0A2R8YDH3_HUMAN,tr|A0A2R8YDT5|A0A2R8YDT5_HUMAN,tr|A0A2R8Y645|A0A2R8Y645_HUMAN,tr|A0A2R8YF78|A0A2R8YF78_HUMAN,tr|A0A0D9SFB3|A0A0D9SFB3_HUMAN,tr|A0A2R8YFS5|A0A2R8YFS5_HUMAN,tr|A0A0D9SF53|A0A0D9SF53_HUMAN,tr|A0A0J9YVQ7|A0A0J9YVQ7_HUMAN,tr|A0A2R8Y5G6|A0A2R8Y5G6_HUMAN,tr|A0A2R8Y7T2|A0A2R8Y7T2_HUMAN,tr|A0A0D9SG12|A0A0D9SG12_HUMAN,tr|F6S8Q4|F6S8Q4_HUMAN,tr|A0A2U3TZJ9|A0A2U3TZJ9_HUMAN,tr|A0A2R8Y4A4|A0A2R8Y4A4_HUMAN" 17 1263.6578 0.92 44771 10127 3 1263.652103 422.2266 ATP-dependent RNA helicase DDX3X OS=Homo sapiens OX=9606 GN=DDX3X PE=1 SV=3 4.68 2169.6 - 1.63E+06 - - - -4.525 - 1.946 0.377 - 269.5 1 2 0 -0.0057 10 0 0 0 2.65E+08 2.88E+08 - - - 4.6859 0.9995 221125_WJC_METTL3_EV_vs_WT_F04.10128.10128.2 6.02E-05 18-Dec K.VTILQSSDSR[166.11].A "sp|Q9ULV3|CIZ1_HUMAN,tr|Q5SYW2|Q5SYW2_HUMAN,tr|F5H2X7|F5H2X7_HUMAN,tr|H0Y5D5|H0Y5D5_HUMAN,tr|A0A494C0L7|A0A494C0L7_HUMAN,tr|Q9BTG3|Q9BTG3_HUMAN" 6 1114.5858 2.32 44772 10128 2 1114.583486 558.3002 Cip1-interacting zinc finger protein OS=Homo sapiens OX=9606 GN=CIZ1 PE=1 SV=2 5.81 2169.8 - 1.37E+06 - - - -2.051 - 2.622 0.284 - 555 1 2 0 -0.0023 10 0 0 0 3.67E+08 1.58E+08 - - - 3.8285 0.9954 221125_WJC_METTL3_EV_vs_WT_F04.10130.10130.2 0.174 14-Sep R.TSWSTVTR.D "sp|O94923|GLCE_HUMAN,tr|H0YNP1|H0YNP1_HUMAN" 2 936.4665 0.49 44774 10130 2 936.463855 469.2405 D-glucuronyl C5-epimerase OS=Homo sapiens OX=9606 GN=GLCE PE=1 SV=3 9.41 2170 - 1.02E+06 - - - -2.8191 - 1.496 0.268 - 203.9 1 2 0 -0.0026 8 0 0 0 1.21E+07 2.50E+07 - - - 2.2344 0.9976 221125_WJC_METTL3_EV_vs_WT_F04.10131.10131.2 0.441 16-Aug K.VK[136.11]PLLQVSR[166.11].Q sp|P35579|MYH9_HUMAN 1 1056.6774 0.93 44775 10131 2 1056.675787 529.346 Myosin-9 OS=Homo sapiens OX=9606 GN=MYH9 PE=1 SV=4 11 2170.1 - 978466 - - - -1.5596 - 1.533 0.236 - 167.3 1 2 0 -0.0016 9 0 0 0 1.99E+07 2.14E+07 - - - 2.0196 0.999 221125_WJC_METTL3_EV_vs_WT_F04.10134.10134.2 0.00863 16-Oct K.DLPEHAVLK[136.11].M "sp|Q00839|HNRPU_HUMAN,tr|A0A1W2PQL0|A0A1W2PQL0_HUMAN,tr|A0A1W2PPL4|A0A1W2PPL4_HUMAN,tr|A0A1W2PQ74|A0A1W2PQ74_HUMAN,tr|Q5RI18|Q5RI18_HUMAN,tr|A0A1W2PP35|A0A1W2PP35_HUMAN,tr|A0A1W2PPS1|A0A1W2PPS1_HUMAN,tr|A0A1W2PRZ7|A0A1W2PRZ7_HUMAN,tr|A0A1W2PPH7|A0A1W2PPH7_HUMAN,tr|A0A1W2PQD4|A0A1W2PQD4_HUMAN,tr|A0A1W2PP34|A0A1W2PP34_HUMAN,tr|A0A1X7SBS1|A0A1X7SBS1_HUMAN" 12 1028.5746 1.11 44776 10134 2 1028.57246 515.2946 Heterogeneous nuclear ribonucleoprotein U OS=Homo sapiens OX=9606 GN=HNRNPU PE=1 SV=6 5.32 2170.5 - 1.08E+08 - - - -2.0757 - 1.703 0.343 - 278 1 2 0 -0.0021 9 0 0 0 2.61E+09 2.35E+09 - - - 3.114 0.9996 221125_WJC_METTL3_EV_vs_WT_F04.10135.10135.2 0.000213 18-Nov K.VTILQSSDSR.A "sp|Q9ULV3|CIZ1_HUMAN,tr|Q5SYW2|Q5SYW2_HUMAN,tr|F5H2X7|F5H2X7_HUMAN,tr|H0Y5D5|H0Y5D5_HUMAN,tr|A0A494C0L7|A0A494C0L7_HUMAN,tr|Q9BTG3|Q9BTG3_HUMAN" 6 1104.5775 2.29 44777 10135 2 1104.575917 553.296 Cip1-interacting zinc finger protein OS=Homo sapiens OX=9606 GN=CIZ1 PE=1 SV=2 5.81 2170.6 - 4.58E+06 - - - -1.4349 - 2.467 0.295 - 446.7 1 2 0 -0.0016 10 0 0 0 3.56E+08 1.56E+08 - - - 3.7399 0.9907 221125_WJC_METTL3_EV_vs_WT_F04.10139.10139.2 0.000887 13/18 V.ADMALHYANK[136.11].Y "sp|P50990|TCPQ_HUMAN,tr|H7C4C8|H7C4C8_HUMAN" 2 1140.5477 0.35 44781 10139 2 1140.545909 571.2811 T-complex protein 1 subunit theta OS=Homo sapiens OX=9606 GN=CCT8 PE=1 SV=4 6.79 2171 - 784718 - - - -1.5957 - 2.439 0.517 - 502.1 1 1 0 -0.0018 10 0 0 0 1.51E+07 4.32E+07 - - - 5.3477 0.9997 221125_WJC_METTL3_EV_vs_WT_F04.10140.10140.3 0.0403 Oct-36 R.VAMHLVC[160.03]PSR.Y sp|O43505|B4GA1_HUMAN 1 1168.5845 1.29 44782 10140 3 1168.582786 390.5354 "Beta-1,4-glucuronyltransferase 1 OS=Homo sapiens OX=9606 GN=B4GAT1 PE=1 SV=1" 8.23 2171.1 - 717491 - - - -1.483 - 1.824 0.374 - 97.8 1 2 0 -0.0017 10 0 0 0 3.70E+07 2.86E+07 - - - 4.4645 0.999 221125_WJC_METTL3_EV_vs_WT_F04.10142.10142.2 0.000114 14-Sep K.C[160.03]SAC[160.03]NVWR.V "sp|O75534|CSDE1_HUMAN,tr|E9PLT0|E9PLT0_HUMAN" 2 1051.4328 0.37 44783 10142 2 1051.429256 526.7237 Cold shock domain-containing protein E1 OS=Homo sapiens OX=9606 GN=CSDE1 PE=1 SV=2 8.07 2171.3 - 875189 - - - -3.3412 - 1.743 0.484 - 356.9 1 2 0 -0.0035 8 0 0 0 1.30E+07 3.47E+07 - - - 4.2904 0.9996 221125_WJC_METTL3_EV_vs_WT_F04.10144.10144.3 0.00298 Sep-40 K.VADMALHYANK.Y "sp|P50990|TCPQ_HUMAN,tr|H7C4C8|H7C4C8_HUMAN" 2 1231.6019 0.35 44784 10144 3 1231.599573 411.5413 T-complex protein 1 subunit theta OS=Homo sapiens OX=9606 GN=CCT8 PE=1 SV=4 6.71 2171.6 - 3.58E+06 - - - -1.9243 - 2.103 0.338 - 152.2 1 2 0 -0.0024 11 0 0 0 2.15E+08 6.23E+08 - - - 4.4195 0.9992 221125_WJC_METTL3_EV_vs_WT_F04.10145.10145.2 0.000302 18-Aug R.AEEGFTQVTR[166.11].K "sp|Q9NRX1|PNO1_HUMAN,tr|F8WBJ6|F8WBJ6_HUMAN" 2 1146.5545 0.73 44785 10145 2 1146.551447 574.2845 RNA-binding protein PNO1 OS=Homo sapiens OX=9606 GN=PNO1 PE=1 SV=1 4.53 2171.6 - 2.46E+06 - - - -2.6383 - 1.597 0.475 - 241.4 1 2 0 -0.003 10 0 0 0 4.19E+07 5.72E+07 - - - 3.8551 0.9994 221125_WJC_METTL3_EV_vs_WT_F04.10146.10146.2 0.000243 13/20 K.VADMALHYANK[136.11].Y "sp|P50990|TCPQ_HUMAN,tr|H7C4C8|H7C4C8_HUMAN" 2 1239.6161 0.36 44786 10146 2 1239.612756 620.8153 T-complex protein 1 subunit theta OS=Homo sapiens OX=9606 GN=CCT8 PE=1 SV=4 6.71 2171.7 - 3.09E+06 - - - -2.7323 - 2.354 0.415 - 621.3 1 2 0 -0.0034 11 0 0 0 5.73E+07 1.58E+08 - - - 4.4211 0.9994 221125_WJC_METTL3_EV_vs_WT_F04.10147.10147.2 0.0181 20-Nov R.IQEQVQQTLAR.K "sp|Q99959|PKP2_HUMAN,tr|A0A087WXY2|A0A087WXY2_HUMAN" 2 1312.7099 1.6 44787 10147 2 1312.706444 657.3622 Plakophilin-2 OS=Homo sapiens OX=9606 GN=PKP2 PE=1 SV=2 6 2171.8 - 1.50E+06 - - - -2.6426 - 2.479 0.388 - 550.3 1 2 0 -0.0035 11 0 0 0 2.99E+07 1.87E+07 - - - 4.3616 0.9999 221125_WJC_METTL3_EV_vs_WT_F04.10148.10148.2 1.92E-07 13/22 R.AYGPYTPQPQPK.D sp|Q12948|FOXC1_HUMAN 1 1345.6667 1.78 44788 10148 2 1345.665181 673.8406 Forkhead box protein C1 OS=Homo sapiens OX=9606 GN=FOXC1 PE=1 SV=3 8.54 2171.9 - 1.38E+06 - - - -1.0931 - 2.326 0.58 - 632.6 1 2 0 -0.0015 12 0 0 0 1.92E+08 1.08E+08 - - - 5.5455 1 221125_WJC_METTL3_EV_vs_WT_F04.10150.10150.2 4.34E-08 13/20 K.TPAQYDASELK.A "sp|P07355|ANXA2_HUMAN,sp|A6NMY6|AXA2L_HUMAN,tr|H0YMU9|H0YMU9_HUMAN,tr|H0YKX9|H0YKX9_HUMAN,tr|H0YMM1|H0YMM1_HUMAN,tr|H0YLV6|H0YLV6_HUMAN,tr|H0YM50|H0YM50_HUMAN,tr|H0YMD0|H0YMD0_HUMAN,tr|H0YMW4|H0YMW4_HUMAN,tr|H0YN42|H0YN42_HUMAN,tr|A0A7I2V4P4|A0A7I2V4P4_HUMAN,tr|H0YNP5|H0YNP5_HUMAN,tr|H0YMT9|H0YMT9_HUMAN,tr|H0YKZ7|H0YKZ7_HUMAN,tr|H0YNB8|H0YNB8_HUMAN,tr|H0YKS4|H0YKS4_HUMAN" 16 1221.5877 2.75 44790 10150 2 1221.588687 611.8011 Annexin A2 OS=Homo sapiens OX=9606 GN=ANXA2 PE=1 SV=2 4.37 2172.2 - 680119 - - - 0.781 - 2.454 0.578 - 358.5 1 2 0 0.001 11 0 0 0 2.39E+08 8.70E+07 - - - 5.7384 0.9993 221125_WJC_METTL3_EV_vs_WT_F04.10151.10151.2 7.54E-05 18-Jul R.DLETSC[160.03]SDIR[166.11].Q "sp|Q14203|DCTN1_HUMAN,tr|A0A804CDA6|A0A804CDA6_HUMAN,tr|E7EX90|E7EX90_HUMAN,tr|A0A7P0Z4C3|A0A7P0Z4C3_HUMAN,tr|Q6AWB1|Q6AWB1_HUMAN" 5 1204.5269 1.87 44791 10151 2 1204.524449 603.2707 Dynactin subunit 1 OS=Homo sapiens OX=9606 GN=DCTN1 PE=1 SV=3 4.03 2172.3 - 579641 - - - -2.0655 - 1.79 0.397 - 121 1 2 0 -0.0025 10 0 0 0 1.17E+08 6.24E+07 - - - 3.5976 0.9563 221125_WJC_METTL3_EV_vs_WT_F04.10152.10152.3 0.646 Dec-40 R.ILSHLQQDSLK[136.11].L "sp|Q9NY93|DDX56_HUMAN,tr|F8WDT8|F8WDT8_HUMAN,tr|G3V0G3|G3V0G3_HUMAN,tr|H7C3E9|H7C3E9_HUMAN" 4 1288.7231 1.02 44792 10152 3 1288.721495 430.5816 Probable ATP-dependent RNA helicase DDX56 OS=Homo sapiens OX=9606 GN=DDX56 PE=1 SV=1 6.74 2172.5 - 843503 - - - -1.2074 - 1.32 0.149 - 89.7 1 2 0 -0.0016 11 0 0 0 1.38E+07 1.36E+07 - - - 0.9895 0.999 221125_WJC_METTL3_EV_vs_WT_F04.10153.10153.2 0.00954 18-Jul K.VVWVEESDK[136.11]R[166.11].S "sp|O00571|DDX3X_HUMAN,tr|A0A2R8YFR4|A0A2R8YFR4_HUMAN,tr|A0A2R8YCW1|A0A2R8YCW1_HUMAN,tr|A0A2R8YDH3|A0A2R8YDH3_HUMAN,tr|A0A2R8YDT5|A0A2R8YDT5_HUMAN,tr|A0A2R8Y645|A0A2R8Y645_HUMAN,tr|A0A2R8YF78|A0A2R8YF78_HUMAN,tr|A0A0D9SFB3|A0A0D9SFB3_HUMAN,tr|A0A2R8YFS5|A0A2R8YFS5_HUMAN,tr|A0A0D9SF53|A0A0D9SF53_HUMAN,tr|A0A0J9YVQ7|A0A0J9YVQ7_HUMAN,tr|A0A2R8Y5G6|A0A2R8Y5G6_HUMAN,tr|A0A2R8Y7T2|A0A2R8Y7T2_HUMAN,tr|A0A0D9SG12|A0A0D9SG12_HUMAN,tr|F6S8Q4|F6S8Q4_HUMAN,tr|A0A2U3TZJ9|A0A2U3TZJ9_HUMAN,tr|A0A2R8Y4A4|A0A2R8Y4A4_HUMAN" 17 1263.6578 1.53 44793 10153 2 1263.654547 632.8362 ATP-dependent RNA helicase DDX3X OS=Homo sapiens OX=9606 GN=DDX3X PE=1 SV=3 4.68 2172.6 - 396536 - - - -2.5909 - 1.538 0.453 - 179.2 1 2 0 -0.0033 10 0 0 0 3.71E+07 2.43E+07 - - - 3.5874 0.9999 221125_WJC_METTL3_EV_vs_WT_F04.10157.10157.2 2.31E-05 14-Oct K.C[160.03]SAC[160.03]NVWR[166.11].V "sp|O75534|CSDE1_HUMAN,tr|E9PLT0|E9PLT0_HUMAN" 2 1061.441 0.37 44795 10157 2 1061.439726 531.7278 Cold shock domain-containing protein E1 OS=Homo sapiens OX=9606 GN=CSDE1 PE=1 SV=2 8.07 2173.1 - 1.78E+06 - - - -1.237 - 2.012 0.553 - 705 1 2 0 -0.0013 8 0 0 0 1.30E+07 3.47E+07 - - - 5.2336 0.9755 221125_WJC_METTL3_EV_vs_WT_F04.10158.10158.2 2.99E-06 18-Oct S.AMMGAVAEK[136.11]K[136.11].G "sp|Q86U44|MTA70_HUMAN,tr|F5H6D8|F5H6D8_HUMAN,tr|H0YFV6|H0YFV6_HUMAN,tr|B4DTN4|B4DTN4_HUMAN" 4 1050.5537 0.19 44796 10158 2 1050.550681 526.2841 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 8.64 2173.2 - 1.52E+06 - - - -2.8471 - 2.161 0.533 - 329.1 1 1 0 -0.003 10 0 0 0 2.24E+07 1.19E+08 - - - 5.1277 0.8738 221125_WJC_METTL3_EV_vs_WT_F04.10160.10160.2 0.0195 14-Aug R.EEAIQNFK[136.11].A "sp|O14776|TCRG1_HUMAN,tr|A0A7P0T8N8|A0A7P0T8N8_HUMAN,tr|G3V220|G3V220_HUMAN" 3 985.496 0.85 44798 10160 2 985.489185 493.7553 Transcription elongation regulator 1 OS=Homo sapiens OX=9606 GN=TCERG1 PE=1 SV=2 4.53 2173.4 - 917963 - - - -6.9265 - 1.366 0.246 - 209.8 1 2 0 -0.0068 8 0 0 0 3.36E+07 3.95E+07 - - - 1.7964 0.9939 221125_WJC_METTL3_EV_vs_WT_F04.10161.10161.3 1.25 13/40 R.ILSHLQQDSLK.L "sp|Q9NY93|DDX56_HUMAN,tr|F8WDT8|F8WDT8_HUMAN,tr|G3V0G3|G3V0G3_HUMAN,tr|H7C3E9|H7C3E9_HUMAN" 4 1280.7089 1.02 44799 10161 3 1280.70627 427.9102 Probable ATP-dependent RNA helicase DDX56 OS=Homo sapiens OX=9606 GN=DDX56 PE=1 SV=1 6.74 2173.5 - 669722 - - - -2.0153 - 2.127 0.162 - 228.8 1 2 0 -0.0026 11 0 0 0 1.38E+07 1.36E+07 - - - 2.4894 0.999 221125_WJC_METTL3_EV_vs_WT_F04.10166.10166.2 0.00736 14-Aug R.EEAIQNFK.A "sp|O14776|TCRG1_HUMAN,tr|A0A7P0T8N8|A0A7P0T8N8_HUMAN,tr|G3V220|G3V220_HUMAN" 3 977.4818 0.85 44802 10166 2 977.481021 489.7482 Transcription elongation regulator 1 OS=Homo sapiens OX=9606 GN=TCERG1 PE=1 SV=2 4.53 2174.2 - 1.78E+06 - - - -0.8082 - 1.321 0.345 - 247 1 2 0 -0.0008 8 0 0 0 3.36E+07 3.95E+07 - - - 2.4285 0.9982 221125_WJC_METTL3_EV_vs_WT_F04.10167.10167.2 0.00052 18-Oct K.SEFEQNLSEK.L "sp|Q16891|MIC60_HUMAN,tr|B9A067|B9A067_HUMAN,tr|C9J406|C9J406_HUMAN,tr|H7C463|H7C463_HUMAN" 4 1209.5513 1.58 44803 10167 2 1209.546547 605.7829 MICOS complex subunit MIC60 OS=Homo sapiens OX=9606 GN=IMMT PE=1 SV=1 4.25 2174.3 - 1.67E+06 - - - -3.9684 - 2.033 0.42 - 412.9 1 2 0 -0.0048 10 0 0 0 5.27E+07 3.32E+07 - - - 4.1221 0.9998 221125_WJC_METTL3_EV_vs_WT_F04.10168.10168.2 2.08E-07 22-Dec K.VVTDTDETELAR[166.11].Q sp|P05198|IF2A_HUMAN 1 1357.6601 1.09 44804 10168 2 1357.657221 679.8373 Eukaryotic translation initiation factor 2 subunit 1 OS=Homo sapiens OX=9606 GN=EIF2S1 PE=1 SV=3 3.92 2174.4 - 1.44E+06 - - - -2.0904 - 2.375 0.577 - 393.8 1 2 0 -0.0028 12 0 0 0 1.89E+08 1.73E+08 - - - 5.5778 0.9999 221125_WJC_METTL3_EV_vs_WT_F04.10175.10175.2 0.000516 18-Sep R.DLETSC[160.03]SDIR.Q "sp|Q14203|DCTN1_HUMAN,tr|A0A804CDA6|A0A804CDA6_HUMAN,tr|E7EX90|E7EX90_HUMAN,tr|A0A7P0Z4C3|A0A7P0Z4C3_HUMAN,tr|Q6AWB1|Q6AWB1_HUMAN" 5 1194.5187 1.87 44809 10175 2 1194.517419 598.2666 Dynactin subunit 1 OS=Homo sapiens OX=9606 GN=DCTN1 PE=1 SV=3 4.03 2175.2 - 4.39E+06 - - - -1.0448 - 2.045 0.516 - 231.1 1 2 0 -0.0012 10 0 0 0 1.17E+08 6.24E+07 - - - 4.8487 0.8062 221125_WJC_METTL3_EV_vs_WT_F04.10176.10176.2 0.438 14-Oct D.LPEHAVLK.M "sp|Q00839|HNRPU_HUMAN,tr|A0A1W2PQL0|A0A1W2PQL0_HUMAN,tr|A0A1W2PPL4|A0A1W2PPL4_HUMAN,tr|A0A1W2PQ74|A0A1W2PQ74_HUMAN,tr|Q5RI18|Q5RI18_HUMAN,tr|A0A1W2PP35|A0A1W2PP35_HUMAN,tr|A0A1W2PPS1|A0A1W2PPS1_HUMAN,tr|A0A1W2PRZ7|A0A1W2PRZ7_HUMAN,tr|A0A1W2PPH7|A0A1W2PPH7_HUMAN,tr|A0A1W2PQD4|A0A1W2PQD4_HUMAN,tr|A0A1W2PP34|A0A1W2PP34_HUMAN,tr|A0A1X7SBS1|A0A1X7SBS1_HUMAN" 12 905.5335 1.03 44810 10176 2 905.53212 453.774 Heterogeneous nuclear ribonucleoprotein U OS=Homo sapiens OX=9606 GN=HNRNPU PE=1 SV=6 6.75 2175.3 - 1.69E+06 - - - -1.471 - 1.723 0.122 - 282 1 1 0 -0.0013 8 0 0 0 4.10E+07 3.99E+07 - - - 1.5826 0.8027 221125_WJC_METTL3_EV_vs_WT_F04.10180.10180.2 0.365 18-Aug S.LSSTLSNTSK[136.11].E "sp|Q86TI0|TBCD1_HUMAN,tr|H7C380|H7C380_HUMAN,tr|H7C0Z7|H7C0Z7_HUMAN,tr|H0Y8P0|H0Y8P0_HUMAN,tr|C9JIE2|C9JIE2_HUMAN" 5 1044.5543 0.07 44812 10180 2 1044.556134 523.2844 TBC1 domain family member 1 OS=Homo sapiens OX=9606 GN=TBC1D1 PE=1 SV=2 8.75 2175.8 - 849889 - - - 1.7998 - 1.518 0.215 - 151.4 1 1 0 0.0019 10 0 0 0 1.83E+06 2.71E+07 - - - 1.7935 0.9992 221125_WJC_METTL3_EV_vs_WT_F04.10182.10182.2 0.000626 18-Nov R.ASAVSELSPR[166.11].E "sp|Q9Y2W1|TR150_HUMAN,tr|A0A3B3ITZ9|A0A3B3ITZ9_HUMAN" 2 1025.5381 2.98 44814 10182 2 1025.536425 513.7763 Thyroid hormone receptor-associated protein 3 OS=Homo sapiens OX=9606 GN=THRAP3 PE=1 SV=2 6.05 2176 - 5.67E+07 - - - -1.6274 - 2.153 0.249 - 508.9 1 2 0 -0.0017 10 0 0 0 3.46E+09 1.16E+09 - - - 3.0201 0.9969 221125_WJC_METTL3_EV_vs_WT_F04.10183.10183.2 0.0116 18-Jul K.EETQPPVALK[136.11].K sp|Q8NC51|PAIRB_HUMAN 1 1118.6063 0.88 44815 10183 2 1118.6048 560.3104 Plasminogen activator inhibitor 1 RNA-binding protein OS=Homo sapiens OX=9606 GN=SERBP1 PE=1 SV=2 4.53 2176 - 3.83E+06 - - - -1.332 - 1.335 0.252 - 138.5 1 2 0 -0.0015 10 0 0 0 1.90E+08 2.17E+08 - - - 1.7083 0.99 221125_WJC_METTL3_EV_vs_WT_F04.10184.10184.2 0.109 16-May R.FPGYDSESK[136.11].E "sp|P46777|RL5_HUMAN,tr|A0A2R8Y6J3|A0A2R8Y6J3_HUMAN" 2 1036.4593 0.15 44816 10184 2 1036.460693 519.2369 60S ribosomal protein L5 OS=Homo sapiens OX=9606 GN=RPL5 PE=1 SV=3 4.37 2176.1 - 2.10E+06 - - - 1.3527 - 0.941 0.28 - 51.3 1 2 0 0.0014 9 0 0 0 8.47E+06 5.70E+07 - - - 0.9327 0.9646 221125_WJC_METTL3_EV_vs_WT_F04.10185.10185.2 4.68 14-Jul R.K[136.11]NGFVVLK[136.11].G "sp|P63241|IF5A1_HUMAN,sp|Q9GZV4|IF5A2_HUMAN,sp|Q6IS14|IF5AL_HUMAN,tr|C9J4W5|C9J4W5_HUMAN,tr|I3L397|I3L397_HUMAN,tr|I3L504|I3L504_HUMAN,tr|C9J7B5|C9J7B5_HUMAN,tr|F8WCJ1|F8WCJ1_HUMAN" 8 919.5826 0.82 44817 10185 2 919.580868 460.7986 Eukaryotic translation initiation factor 5A-1 OS=Homo sapiens OX=9606 GN=EIF5A PE=1 SV=2 10 2176.2 - 742141 - - - -1.8704 - 1.209 0.082 - 138.5 1 2 0 -0.0017 8 0 0 0 2.56E+07 3.11E+07 - - - 0.2185 0.9938 221125_WJC_METTL3_EV_vs_WT_F04.10188.10188.2 0.000324 20-Oct L.SAMMGAVAEK[136.11]K[136.11].G "sp|Q86U44|MTA70_HUMAN,tr|F5H6D8|F5H6D8_HUMAN,tr|H0YFV6|H0YFV6_HUMAN,tr|B4DTN4|B4DTN4_HUMAN" 4 1137.5857 0.03 44818 10188 2 1137.58444 569.8001 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 8.31 2176.6 - 8.15E+06 - - - -1.1085 - 2.203 0.607 - 319.7 1 1 0 -0.0013 11 0 0 0 8.95E+06 2.63E+08 - - - 5.6606 0.9824 221125_WJC_METTL3_EV_vs_WT_F04.10194.10194.3 0.266 Oct-44 R.AYGPYTPQPQPK.D sp|Q12948|FOXC1_HUMAN 1 1345.6667 1.04 44821 10194 3 1345.665949 449.5628 Forkhead box protein C1 OS=Homo sapiens OX=9606 GN=FOXC1 PE=1 SV=3 8.54 2177.2 - 701926 - - - -0.5224 - 1.585 0.148 - 101.2 1 2 0 -0.0007 12 0 0 0 2.89E+07 2.79E+07 - - - 1.4665 0.9992 221125_WJC_METTL3_EV_vs_WT_F04.10196.10196.2 0.0704 18-Nov R.RAPLAAGTWR.S sp|Q9Y5V3|MAGD1_HUMAN 1 1097.6094 3.07 44823 10196 2 1097.608905 549.812 Melanoma-associated antigen D1 OS=Homo sapiens OX=9606 GN=MAGED1 PE=1 SV=3 12 2177.5 - 975827 - - - -0.461 - 1.563 0.304 - 186.3 1 2 0 -0.0005 10 0 0 0 1.77E+07 5.77E+06 - - - 2.5328 0.9999 221125_WJC_METTL3_EV_vs_WT_F04.10199.10199.2 9.35E-06 26-Nov K.AAVEDSGTTVETIK[136.11].L "sp|Q5VTR2|BRE1A_HUMAN,tr|C9JWJ4|C9JWJ4_HUMAN,tr|C9JXC9|C9JXC9_HUMAN,tr|C9J0A5|C9J0A5_HUMAN" 4 1427.7235 0.89 44824 10199 2 1427.722874 714.869 E3 ubiquitin-protein ligase BRE1A OS=Homo sapiens OX=9606 GN=RNF20 PE=1 SV=2 4.14 2177.9 - 363516 - - - -0.4413 - 2.584 0.541 - 511 1 2 0 -0.0006 14 0 0 0 5.86E+06 6.58E+06 - - - 5.4189 0.9997 221125_WJC_METTL3_EV_vs_WT_F04.10201.10201.3 8.90E-05 13/36 K.LFKPPQPPAR.M "sp|O15372|EIF3H_HUMAN,tr|B3KS98|B3KS98_HUMAN,tr|A0A087WZK9|A0A087WZK9_HUMAN" 3 1149.6659 1.95 44825 10201 3 1149.663158 384.2292 Eukaryotic translation initiation factor 3 subunit H OS=Homo sapiens OX=9606 GN=EIF3H PE=1 SV=1 11 2178.1 - 2.03E+06 - - - -2.3537 - 1.953 0.388 - 240.8 1 2 0 -0.0027 10 0 0 0 5.90E+07 3.02E+07 - - - 4.8199 0.9999 221125_WJC_METTL3_EV_vs_WT_F04.10203.10203.2 8.36E-05 13/20 R.VVDSMEDEVQR[166.11].R "sp|Q9Y285|SYFA_HUMAN,tr|K7ER16|K7ER16_HUMAN,tr|K7ER00|K7ER00_HUMAN" 3 1315.5954 2.39 44827 10203 2 1315.594655 658.805 Phenylalanine--tRNA ligase alpha subunit OS=Homo sapiens OX=9606 GN=FARSA PE=1 SV=3 3.92 2178.4 - 634364 - - - -0.529 - 2.513 0.535 - 536.5 1 2 0 -0.0007 11 0 0 0 5.50E+07 2.30E+07 - - - 5.4851 0.9987 221125_WJC_METTL3_EV_vs_WT_F04.10207.10207.2 0.136 18-Oct K.YLQSNSNNWR[166.11].W sp|Q7Z6Z7|HUWE1_HUMAN 1 1290.5981 0.12 44829 10207 2 1290.596197 646.3063 E3 ubiquitin-protein ligase HUWE1 OS=Homo sapiens OX=9606 GN=HUWE1 PE=1 SV=3 8.75 2178.9 - 603123 - - - -1.4497 - 1.699 0.27 - 353.8 1 2 0 -0.0019 10 0 0 0 1.82E+06 1.49E+07 - - - 2.5141 0.9803 221125_WJC_METTL3_EV_vs_WT_F04.10209.10209.3 0.256 Jul-32 R.LHEEGIIYR[166.11].S "sp|P26640|SYVC_HUMAN,tr|A0A140T936|A0A140T936_HUMAN" 2 1138.601 0.001 44831 10209 3 1138.598605 380.541 Valine--tRNA ligase OS=Homo sapiens OX=9606 GN=VARS1 PE=1 SV=4 5.4 2179.1 - 614395 - - - -2.1281 - 1.555 0.186 - 73.7 2 2 0 -0.0024 9 0 0 0 0.00E+00 1.28E+07 - - - 1.8042 0.9994 221125_WJC_METTL3_EV_vs_WT_F04.10211.10211.2 9.98E-05 18-Dec R.ASAVSELSPR.E "sp|Q9Y2W1|TR150_HUMAN,tr|A0A3B3ITZ9|A0A3B3ITZ9_HUMAN" 2 1015.5298 2.99 44832 10211 2 1015.528658 508.7722 Thyroid hormone receptor-associated protein 3 OS=Homo sapiens OX=9606 GN=THRAP3 PE=1 SV=2 6.05 2179.4 - 8.06E+07 - - - -1.1482 - 2.292 0.241 - 564.8 1 2 0 -0.0012 10 0 0 0 3.45E+09 1.16E+09 - - - 3.1358 0.9987 221125_WJC_METTL3_EV_vs_WT_F04.10216.10216.2 0.0113 12-Jul R.EHIYDLR[166.11].S sp|Q14677|EPN4_HUMAN 1 954.4799 1.53 44836 10216 2 954.479497 478.2472 Clathrin interactor 1 OS=Homo sapiens OX=9606 GN=CLINT1 PE=1 SV=1 5.32 2179.9 - 1.09E+06 - - - -0.3698 - 1.537 0.237 - 275.9 1 2 0 -0.0004 7 0 0 0 2.11E+08 1.38E+08 - - - 2.1533 0.98 221125_WJC_METTL3_EV_vs_WT_F04.10217.10217.2 1.37 18-Jul K.YQESPGIQMK.T "sp|Q9UHI6|DDX20_HUMAN,tr|A0A7P0T9T8|A0A7P0T9T8_HUMAN" 2 1179.5594 0.47 44837 10217 2 1179.557078 590.787 Probable ATP-dependent RNA helicase DDX20 OS=Homo sapiens OX=9606 GN=DDX20 PE=1 SV=2 6 2180 - 682497 - - - -1.9762 - 1.244 0.136 - 80.9 1 2 0 -0.0023 10 0 0 0 1.12E+07 2.37E+07 - - - 0.6542 1 221125_WJC_METTL3_EV_vs_WT_F04.10221.10221.3 2.36E-05 13/44 K.LSAMMGAVAEKK[136.11].G "sp|Q86U44|MTA70_HUMAN,tr|F5H6D8|F5H6D8_HUMAN,tr|H0YFV6|H0YFV6_HUMAN,tr|B4DTN4|B4DTN4_HUMAN" 4 1242.6556 - 44839 10221 3 1242.657037 415.2258 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 8.59 2180.6 - 5.43E+06 - - - 1.1846 - 2.535 0.511 - 208.1 1 2 0 0.0015 12 0 0 0 - - - - - 6.8151 0.9866 221125_WJC_METTL3_EV_vs_WT_F04.10222.10222.2 7.35E-05 20-Nov N.LQNAIADAEQR.G "sp|P13647|K2C5_HUMAN,tr|H0YI76|H0YI76_HUMAN" 2 1227.6208 124.43 44840 10222 2 1227.619116 614.8177 "Keratin, type II cytoskeletal 5 OS=Homo sapiens OX=9606 GN=KRT5 PE=1 SV=3" 4.37 2180.6 - 1.80E+06 - - - -1.3424 - 2.42 0.403 - 503.7 1 1 0 -0.0016 11 0 0 0 3.94E+07 3.17E+05 - - - 4.4078 0.9982 221125_WJC_METTL3_EV_vs_WT_F04.10226.10226.2 0.0368 18-Jul K.YQESPGIQMK[136.11].T "sp|Q9UHI6|DDX20_HUMAN,tr|A0A7P0T9T8|A0A7P0T9T8_HUMAN" 2 1187.5736 0.88 44844 10226 2 1187.574363 594.7941 Probable ATP-dependent RNA helicase DDX20 OS=Homo sapiens OX=9606 GN=DDX20 PE=1 SV=2 6 2181.1 - 400530 - - - 0.6349 - 1.305 0.295 - 98.4 1 2 0 0.0008 10 0 0 0 1.08E+07 1.23E+07 - - - 1.9627 0.9985 221125_WJC_METTL3_EV_vs_WT_F04.10230.10230.2 0.0427 12-Jul R.EHIYDLR.S sp|Q14677|EPN4_HUMAN 1 944.4716 1.53 44846 10230 2 944.47018 473.2431 Clathrin interactor 1 OS=Homo sapiens OX=9606 GN=CLINT1 PE=1 SV=1 5.32 2181.6 - 2.51E+06 - - - -1.4823 - 1.55 0.265 - 274.2 1 2 0 -0.0014 7 0 0 0 2.10E+08 1.38E+08 - - - 2.3865 0.9991 221125_WJC_METTL3_EV_vs_WT_F04.10231.10231.2 0.00025 20-Dec R.LWSAQQGNSVR.L sp|O75529|TAF5L_HUMAN 1 1244.6262 1.38 44847 10231 2 1244.621862 623.3204 TAF5-like RNA polymerase II p300\CBP-associated factor-associated factor 65 kDa subunit 5L OS=Homo sapiens OX=9606 GN=TAF5L PE=1 SV=1 9.75 2181.7 - 844024 - - - -3.4725 - 2.094 0.487 - 394.8 1 2 0 -0.0043 11 0 0 0 2.68E+07 1.94E+07 - - - 4.636 0.8939 221125_WJC_METTL3_EV_vs_WT_F04.10232.10232.2 2.18 20-Jul R.GSPTGGAQLLK[136.11].R sp|Q14684|RRP1B_HUMAN 1 1035.5804 1.1 44848 10232 2 1035.581992 518.7975 Ribosomal RNA processing protein 1 homolog B OS=Homo sapiens OX=9606 GN=RRP1B PE=1 SV=3 8.75 2181.8 - 730905 - - - 1.5286 - 1.15 0.027 - 127.8 3 2 0 0.0016 11 0 0 0 3.03E+07 2.76E+07 - - - -0.5951 0.9765 221125_WJC_METTL3_EV_vs_WT_F04.10237.10237.2 0.215 12-May K.DNNLLGR[166.11].F "sp|P0DMV8|HS71A_HUMAN,sp|P34931|HS71L_HUMAN,sp|P0DMV9|HS71B_HUMAN,sp|P17066|HSP76_HUMAN,tr|Q53FA3|Q53FA3_HUMAN,tr|V9GZ37|V9GZ37_HUMAN,tr|A0A0G2JIW1|A0A0G2JIW1_HUMAN" 7 810.4223 0.14 44851 10237 2 810.419651 406.2184 Heat shock 70 kDa protein 1A OS=Homo sapiens OX=9606 GN=HSPA1A PE=1 SV=1 5.84 2182.4 - 583145 - - - -3.3131 - 1.237 0.222 - 150.9 2 2 0 -0.0027 7 0 0 0 2.10E+08 1.45E+09 - - - 1.2193 0.9985 221125_WJC_METTL3_EV_vs_WT_F04.10238.10238.2 0.631 14-Jul R.NTEDEILK[136.11].A sp|Q99459|CDC5L_HUMAN 1 968.4906 1.83 44852 10238 2 968.490626 485.2526 Cell division cycle 5-like protein OS=Homo sapiens OX=9606 GN=CDC5L PE=1 SV=2 4.14 2182.5 - 590092 - - - 0.0361 - 1.431 0.261 - 239.4 1 2 0 0 8 0 0 0 1.06E+08 5.78E+07 - - - 2.0496 0.9981 221125_WJC_METTL3_EV_vs_WT_F04.10239.10239.3 0.164 Nov-40 R.LNQLK[136.11]PGLQYK[136.11].L sp|Q12906|ILF3_HUMAN 1 1316.7787 1.09 44853 10239 3 1316.778577 439.9335 Interleukin enhancer-binding factor 3 OS=Homo sapiens OX=9606 GN=ILF3 PE=1 SV=3 9.7 2182.6 - 468079 - - - -0.1101 - 1.912 0.222 - 113.3 1 2 0 -0.0001 11 0 0 0 1.66E+08 1.52E+08 - - - 2.8563 0.9995 221125_WJC_METTL3_EV_vs_WT_F04.10242.10242.2 0.00288 14-Nov R.KNGFVVLK.G "sp|P63241|IF5A1_HUMAN,sp|Q9GZV4|IF5A2_HUMAN,sp|Q6IS14|IF5AL_HUMAN,tr|C9J4W5|C9J4W5_HUMAN,tr|I3L397|I3L397_HUMAN,tr|I3L504|I3L504_HUMAN,tr|C9J7B5|C9J7B5_HUMAN,tr|F8WCJ1|F8WCJ1_HUMAN" 8 903.5542 0.82 44855 10242 2 903.554353 452.7844 Eukaryotic translation initiation factor 5A-1 OS=Homo sapiens OX=9606 GN=EIF5A PE=1 SV=2 10 2183 - 980148 - - - 0.1826 - 2.057 0.237 - 406.2 1 2 0 0.0002 8 0 0 0 2.56E+07 3.11E+07 - - - 2.9667 0.9998 221125_WJC_METTL3_EV_vs_WT_F04.10244.10244.3 0.01 Sep-40 R.LNQLKPGLQYK.L sp|Q12906|ILF3_HUMAN 1 1300.7503 1.09 44856 10244 3 1300.750693 434.5907 Interleukin enhancer-binding factor 3 OS=Homo sapiens OX=9606 GN=ILF3 PE=1 SV=3 9.7 2183.2 - 600108 - - - 0.2852 - 2.077 0.345 - 108.2 1 2 0 0.0004 11 0 0 0 1.66E+08 1.52E+08 - - - 4.4627 0.9997 221125_WJC_METTL3_EV_vs_WT_F04.10246.10246.2 0.000179 18-Nov R.LILC[160.03]C[160.03]NSTSK.V sp|P40938|RFC3_HUMAN 1 1194.5737 1.33 44857 10246 2 1194.574706 598.2941 Replication factor C subunit 3 OS=Homo sapiens OX=9606 GN=RFC3 PE=1 SV=2 8.06 2183.4 - 477981 - - - 0.8589 - 1.8 0.442 - 323.8 1 2 0 0.001 10 0 0 0 1.21E+07 9.09E+06 - - - 3.946 0.9989 221125_WJC_METTL3_EV_vs_WT_F04.10247.10247.2 0.0962 26-May K.AAVEDSGTTVETIK.L "sp|Q5VTR2|BRE1A_HUMAN,tr|C9JWJ4|C9JWJ4_HUMAN,tr|C9JXC9|C9JXC9_HUMAN,tr|C9J0A5|C9J0A5_HUMAN" 4 1419.7093 0.89 44858 10247 2 1419.708122 710.8619 E3 ubiquitin-protein ligase BRE1A OS=Homo sapiens OX=9606 GN=RNF20 PE=1 SV=2 4.14 2183.6 - 141130 - - - -0.8326 - 1.412 0.338 - 57.8 1 2 0 -0.0012 14 0 0 0 5.86E+06 6.58E+06 - - - 2.4029 0.9996 221125_WJC_METTL3_EV_vs_WT_F04.10250.10250.2 0.000155 24-Sep K.GPLLVSTESHPVK.S sp|Q9Y3A4|RRP7A_HUMAN 1 1362.7507 0.96 44861 10250 2 1362.751682 682.3826 Ribosomal RNA-processing protein 7 homolog A OS=Homo sapiens OX=9606 GN=RRP7A PE=1 SV=2 6.75 2183.9 - 255573 - - - 0.7089 - 2.233 0.3 - 272.9 1 2 0 0.001 13 0 0 0 7.08E+06 7.39E+06 - - - 3.3183 1 221125_WJC_METTL3_EV_vs_WT_F04.10253.10253.3 9.58E-06 13/44 K.LSAMMGAVAEK[136.11]K[136.11].G "sp|Q86U44|MTA70_HUMAN,tr|F5H6D8|F5H6D8_HUMAN,tr|H0YFV6|H0YFV6_HUMAN,tr|B4DTN4|B4DTN4_HUMAN" 4 1250.6698 0 44863 10253 3 1250.670792 417.8972 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 8.59 2184.3 - 2.47E+07 - - - 0.8212 - 2.76 0.517 - 227.4 1 2 0 0.001 12 0 0 0 1.61E+07 4.73E+09 - - - 7.1178 0.992 221125_WJC_METTL3_EV_vs_WT_F04.10254.10254.2 0.0543 14-Jul R.NTEDEILK.A sp|Q99459|CDC5L_HUMAN 1 960.4764 1.83 44864 10254 2 960.472147 481.2455 Cell division cycle 5-like protein OS=Homo sapiens OX=9606 GN=CDC5L PE=1 SV=2 4.14 2184.4 - 1.91E+06 - - - -4.4186 - 1.532 0.332 - 293.1 1 2 0 -0.0042 8 0 0 0 1.06E+08 5.81E+07 - - - 2.7783 0.9987 221125_WJC_METTL3_EV_vs_WT_F04.10256.10256.2 0.0444 14-Aug K.DIDIHEVR[166.11].L "sp|Q00839|HNRPU_HUMAN,tr|A0A1W2PQL0|A0A1W2PQL0_HUMAN,tr|A0A1W2PPL4|A0A1W2PPL4_HUMAN,tr|A0A1W2PQ74|A0A1W2PQ74_HUMAN,tr|Q5RI18|Q5RI18_HUMAN,tr|A0A1W2PP35|A0A1W2PP35_HUMAN,tr|A0A1W2PPS1|A0A1W2PPS1_HUMAN,tr|A0A1W2PRZ7|A0A1W2PRZ7_HUMAN,tr|A0A1W2PPH7|A0A1W2PPH7_HUMAN,tr|A0A1W2PP34|A0A1W2PP34_HUMAN,tr|A0A1X7SBS1|A0A1X7SBS1_HUMAN" 11 1005.5119 1.04 44866 10256 2 1005.513396 503.7632 Heterogeneous nuclear ribonucleoprotein U OS=Homo sapiens OX=9606 GN=HNRNPU PE=1 SV=6 4.54 2184.4 - 5.01E+06 - - - 1.5087 - 1.588 0.301 - 238.9 1 2 0 0.0015 8 0 0 0 8.07E+08 7.77E+08 - - - 2.6585 0.9998 221125_WJC_METTL3_EV_vs_WT_F04.10258.10258.2 0.518 18-Nov R.TALTTTISSR.D sp|Q9BV20|MTNA_HUMAN 1 1049.5717 1.64 44868 10258 2 1049.573163 525.7931 Methylthioribose-1-phosphate isomerase OS=Homo sapiens OX=9606 GN=MRI1 PE=1 SV=1 9.41 2184.6 - 1.72E+06 - - - 1.4053 - 2.051 0.492 - 364.5 1 2 0 0.0015 10 0 0 0 3.27E+07 1.99E+07 - - - 4.6795 0.9998 221125_WJC_METTL3_EV_vs_WT_F04.10259.10259.2 0.000145 18-Aug K.DFVEDDTTHG.- sp|Q9UQE7|SMC3_HUMAN 1 1134.4465 - 44869 10259 2 1134.448113 568.2306 Structural maintenance of chromosomes protein 3 OS=Homo sapiens OX=9606 GN=SMC3 PE=1 SV=2 3.84 2184.6 - 1.60E+06 - - - 1.3795 - 1.805 0.615 - 172.2 1 2 0 0.0016 10 0 0 0 - - - - - 5.2313 0.9999 221125_WJC_METTL3_EV_vs_WT_F04.10261.10261.2 0.000214 20-Nov K.FVQC[160.03]PDGELQK.R "sp|Q9Y230|RUVB2_HUMAN,tr|M0R0Y3|M0R0Y3_HUMAN" 2 1319.618 0.96 44871 10261 2 1319.619073 660.8163 RuvB-like 2 OS=Homo sapiens OX=9606 GN=RUVBL2 PE=1 SV=3 4.37 2184.9 - 785700 - - - 0.823 - 2.084 0.518 - 386 1 2 0 0.0011 11 0 0 0 4.12E+07 4.31E+07 - - - 4.853 0.9998 221125_WJC_METTL3_EV_vs_WT_F04.10262.10262.2 4.73E-06 20-Sep K.EYDELAETQGK.L "sp|O60341|KDM1A_HUMAN,tr|R4GMQ1|R4GMQ1_HUMAN" 2 1281.5725 1.16 44872 10262 2 1281.57435 641.7935 Lysine-specific histone demethylase 1A OS=Homo sapiens OX=9606 GN=KDM1A PE=1 SV=2 4 2185 - 697111 - - - 1.4623 - 1.921 0.507 - 233.9 1 2 0 0.0019 11 0 0 0 1.41E+07 1.22E+07 - - - 4.5512 0.9999 221125_WJC_METTL3_EV_vs_WT_F04.10265.10265.2 3.74E-05 24-Oct K.GPLLVSTESHPVK[136.11].S sp|Q9Y3A4|RRP7A_HUMAN 1 1370.7649 0.96 44875 10265 2 1370.764761 686.3897 Ribosomal RNA-processing protein 7 homolog A OS=Homo sapiens OX=9606 GN=RRP7A PE=1 SV=2 6.75 2185.4 - 224122 - - - -0.1131 - 2.337 0.511 - 309.4 1 2 0 -0.0002 13 0 0 0 7.08E+06 7.39E+06 - - - 4.9938 0.9999 221125_WJC_METTL3_EV_vs_WT_F04.10269.10269.2 7.45E-06 20-Dec K.FAEALGSTEAK.A "sp|P78347|GTF2I_HUMAN,tr|A0A494C0Q7|A0A494C0Q7_HUMAN,tr|A0A494C1K3|A0A494C1K3_HUMAN" 3 1122.5557 1.42 44877 10269 2 1122.557029 562.2851 General transcription factor II-I OS=Homo sapiens OX=9606 GN=GTF2I PE=1 SV=2 4.53 2185.9 - 2.46E+06 - - - 1.1803 - 2.547 0.542 - 408.8 1 2 0 0.0013 11 0 0 0 9.29E+07 6.56E+07 - - - 5.573 0.9998 221125_WJC_METTL3_EV_vs_WT_F04.10270.10270.2 0.000136 20-Sep K.FVQC[160.03]PDGELQK[136.11].R "sp|Q9Y230|RUVB2_HUMAN,tr|M0R0Y3|M0R0Y3_HUMAN" 2 1327.6322 0.96 44878 10270 2 1327.633459 664.8234 RuvB-like 2 OS=Homo sapiens OX=9606 GN=RUVBL2 PE=1 SV=3 4.37 2186 - 1.68E+06 - - - 0.9581 - 1.701 0.579 - 267.1 1 2 0 0.0013 11 0 0 0 4.12E+07 4.31E+07 - - - 4.7542 0.9997 221125_WJC_METTL3_EV_vs_WT_F04.10272.10272.2 1.62E-06 20-Dec R.NLAANDLSPSR[166.11].L sp|Q96CB9|NSUN4_HUMAN 1 1166.5919 0.07 44880 10272 2 1166.593746 584.3032 5-methylcytosine rRNA methyltransferase NSUN4 OS=Homo sapiens OX=9606 GN=NSUN4 PE=1 SV=2 5.84 2186.2 - 453327 - - - 1.5652 - 2.411 0.39 - 532 1 2 0 0.0018 11 0 0 0 1.22E+06 1.65E+07 - - - 4.3017 0.9087 221125_WJC_METTL3_EV_vs_WT_F04.10273.10273.3 1.38 14/40 A.PAVTQHAPYFK.G sp|P30048|PRDX3_HUMAN 1 1257.6506 0.8 44881 10273 3 1257.647873 420.2241 "Thioredoxin-dependent peroxide reductase, mitochondrial OS=Homo sapiens OX=9606 GN=PRDX3 PE=1 SV=3" 9.01 2186.3 - 461543 - - - -2.1739 - 2.25 0.272 - 232.4 1 1 0 -0.0027 11 0 0 0 2.01E+07 2.50E+07 - - - 3.8755 0.9995 221125_WJC_METTL3_EV_vs_WT_F04.10274.10274.2 0.000223 16-Sep R.QEMLDDVQK.K "sp|Q15643|TRIPB_HUMAN,tr|H0YJ97|H0YJ97_HUMAN" 2 1104.5121 1.05 44882 10274 2 1104.510725 553.2633 Thyroid receptor-interacting protein 11 OS=Homo sapiens OX=9606 GN=TRIP11 PE=1 SV=3 4.03 2186.4 - 270582 - - - -1.2675 - 1.735 0.369 - 293.4 1 2 0 -0.0014 9 0 0 0 2.49E+07 2.39E+07 - - - 3.3601 0.9997 221125_WJC_METTL3_EV_vs_WT_F04.10278.10278.2 0.00219 16-Aug R.DGLAEEVQR[166.11].L sp|Q16352|AINX_HUMAN 1 1025.5017 1.58 44884 10278 2 1025.501658 513.7581 Alpha-internexin OS=Homo sapiens OX=9606 GN=INA PE=1 SV=2 4.14 2186.9 - 1.99E+06 - - - -0.0488 - 1.765 0.376 - 216.3 1 2 0 -0.0001 9 0 0 0 8.16E+07 5.17E+07 - - - 3.4618 0.9894 221125_WJC_METTL3_EV_vs_WT_F04.10279.10279.2 0.41 12-Jul K.TYTWNTK[136.11].E "sp|O75400|PR40A_HUMAN,tr|F5H578|F5H578_HUMAN,tr|A0A7N4I394|A0A7N4I394_HUMAN" 3 920.4483 0.59 44885 10279 2 920.44817 461.2314 Pre-mRNA-processing factor 40 homolog A OS=Homo sapiens OX=9606 GN=PRPF40A PE=1 SV=2 8.26 2187 - 844890 - - - -0.176 - 1.013 0.202 - 156.9 1 2 0 -0.0002 7 0 0 0 1.91E+07 3.25E+07 - - - 0.5738 0.9995 221125_WJC_METTL3_EV_vs_WT_F04.10280.10280.2 0.00311 16-Nov K.TANLNLETR[166.11].T "sp|Q9UKF6|CPSF3_HUMAN,tr|G5E9W3|G5E9W3_HUMAN" 2 1040.549 0.52 44886 10280 2 1040.55101 521.2818 Cleavage and polyadenylation specificity factor subunit 3 OS=Homo sapiens OX=9606 GN=CPSF3 PE=1 SV=1 5.66 2187.1 - 2.20E+06 - - - 1.9384 - 2.194 0.354 - 577.2 1 2 0 0.002 9 0 0 0 4.35E+07 8.36E+07 - - - 3.9282 0.9999 221125_WJC_METTL3_EV_vs_WT_F04.10283.10283.3 0.00264 13/36 R.AYIC[160.03]AHPLDR[166.11].T "sp|Q9H845|ACAD9_HUMAN,tr|Q9H9W4|Q9H9W4_HUMAN,tr|H0Y8Z9|H0Y8Z9_HUMAN" 3 1224.5949 1.38 44889 10283 3 1224.596033 409.2056 "Complex I assembly factor ACAD9, mitochondrial OS=Homo sapiens OX=9606 GN=ACAD9 PE=1 SV=1" 6.78 2187.4 - 531240 - - - 0.9277 - 2.101 0.464 - 257.4 1 2 0 0.0011 10 0 0 0 1.54E+07 1.12E+07 - - - 5.881 0.9992 221125_WJC_METTL3_EV_vs_WT_F04.10285.10285.2 0.202 20-Aug R.LNQLKPGLQYK.L sp|Q12906|ILF3_HUMAN 1 1300.7503 1.27 44891 10285 2 1300.748862 651.3824 Interleukin enhancer-binding factor 3 OS=Homo sapiens OX=9606 GN=ILF3 PE=1 SV=3 9.7 2187.6 - 241165 - - - -1.1224 - 1.823 0.292 - 262.3 1 2 0 -0.0015 11 0 0 0 1.53E+07 1.21E+07 - - - 2.8217 0.9994 221125_WJC_METTL3_EV_vs_WT_F04.10288.10288.2 0.00181 18-Sep K.TNPEIQSTLR.K sp|P31944|CASPE_HUMAN 1 1157.6041 999 44893 10288 2 1157.605765 579.8093 Caspase-14 OS=Homo sapiens OX=9606 GN=CASP14 PE=1 SV=2 5.66 2188 - 3.40E+06 - - - 1.4806 - 1.58 0.42 - 262.1 1 2 0 0.0017 10 0 0 0 7.39E+07 0.00E+00 - - - 3.4194 0.9996 221125_WJC_METTL3_EV_vs_WT_F04.10290.10290.2 0.0071 16-Sep R.DGLAEEVQR.L sp|Q16352|AINX_HUMAN 1 1015.4934 1.61 44894 10290 2 1015.493492 508.754 Alpha-internexin OS=Homo sapiens OX=9606 GN=INA PE=1 SV=2 4.14 2188.2 - 4.34E+06 - - - 0.0532 - 1.905 0.336 - 280.2 1 2 0 0.0001 9 0 0 0 8.16E+07 5.07E+07 - - - 3.3872 1 221125_WJC_METTL3_EV_vs_WT_F04.10291.10291.3 3.20E-06 Dec-48 K.GPLLVSTESHPVK[136.11].S sp|Q9Y3A4|RRP7A_HUMAN 1 1370.7649 1.08 44895 10291 3 1370.764937 457.9289 Ribosomal RNA-processing protein 7 homolog A OS=Homo sapiens OX=9606 GN=RRP7A PE=1 SV=2 6.75 2188.2 - 2.37E+06 - - - 0.0153 - 2 0.539 - 201.2 1 2 0 0 13 0 0 0 8.64E+07 7.97E+07 - - - 6.4286 0.8061 221125_WJC_METTL3_EV_vs_WT_F04.10295.10295.2 1.04 12-Jun D.IDIHEVR.L "sp|Q00839|HNRPU_HUMAN,tr|A0A1W2PQL0|A0A1W2PQL0_HUMAN,tr|A0A1W2PPL4|A0A1W2PPL4_HUMAN,tr|A0A1W2PQ74|A0A1W2PQ74_HUMAN,tr|Q5RI18|Q5RI18_HUMAN,tr|A0A1W2PP35|A0A1W2PP35_HUMAN,tr|A0A1W2PPS1|A0A1W2PPS1_HUMAN,tr|A0A1W2PRZ7|A0A1W2PRZ7_HUMAN,tr|A0A1W2PPH7|A0A1W2PPH7_HUMAN,tr|A0A1W2PP34|A0A1W2PP34_HUMAN,tr|A0A1X7SBS1|A0A1X7SBS1_HUMAN" 11 880.4767 1.14 44897 10295 2 880.476317 441.2456 Heterogeneous nuclear ribonucleoprotein U OS=Homo sapiens OX=9606 GN=HNRNPU PE=1 SV=6 5.32 2188.8 - 6.00E+06 - - - -0.3964 - 1.467 0.138 - 145.6 1 1 0 -0.0003 7 0 0 0 1.34E+08 1.18E+08 - - - 1.2744 0.9988 221125_WJC_METTL3_EV_vs_WT_F04.10300.10300.2 0.0279 16-Jul R.QEMLDDVQK[136.11].K "sp|Q15643|TRIPB_HUMAN,tr|H0YJ97|H0YJ97_HUMAN" 2 1112.5263 1.27 44900 10300 2 1112.526115 557.2704 Thyroid receptor-interacting protein 11 OS=Homo sapiens OX=9606 GN=TRIP11 PE=1 SV=3 4.03 2189.4 - 987683 - - - -0.1888 - 1.454 0.281 - 111.9 1 2 0 -0.0002 9 0 0 0 3.25E+07 2.56E+07 - - - 2.1993 0.9992 221125_WJC_METTL3_EV_vs_WT_F04.10305.10305.2 0.0107 12-Jun K.DNNLLGR.F "sp|P0DMV8|HS71A_HUMAN,sp|P34931|HS71L_HUMAN,sp|P0DMV9|HS71B_HUMAN,sp|P17066|HSP76_HUMAN,tr|Q53FA3|Q53FA3_HUMAN,tr|V9GZ37|V9GZ37_HUMAN,tr|A0A0G2JIW1|A0A0G2JIW1_HUMAN" 7 800.4141 0.14 44903 10305 2 800.413877 401.2143 Heat shock 70 kDa protein 1A OS=Homo sapiens OX=9606 GN=HSPA1A PE=1 SV=1 5.84 2190 - 6.96E+06 - - - -0.2361 - 1.442 0.317 - 273.6 1 2 0 -0.0002 7 0 0 0 2.04E+08 1.44E+09 - - - 2.5421 0.9991 221125_WJC_METTL3_EV_vs_WT_F04.10308.10308.2 6.38E-07 13/22 K.VLEEANQAINPK[136.11].L "sp|Q92841|DDX17_HUMAN,tr|A0A5H1ZRQ2|A0A5H1ZRQ2_HUMAN,tr|A0A1X7SBZ2|A0A1X7SBZ2_HUMAN" 3 1332.7129 0.96 44906 10308 2 1332.707323 667.3637 Probable ATP-dependent RNA helicase DDX17 OS=Homo sapiens OX=9606 GN=DDX17 PE=1 SV=2 4.53 2190.4 - 574833 - - - -4.1697 - 2.489 0.578 - 510.1 1 2 0 -0.0056 12 0 0 0 2.06E+08 2.15E+08 - - - 5.7077 0.9981 221125_WJC_METTL3_EV_vs_WT_F04.10309.10309.2 0.133 14-Aug R.SEGFDTYR.C sp|P12004|PCNA_HUMAN 1 973.4141 1.4 44907 10309 2 973.414218 487.7143 Proliferating cell nuclear antigen OS=Homo sapiens OX=9606 GN=PCNA PE=1 SV=1 4.37 2190.5 - 468526 - - - 0.0955 - 1.306 0.268 - 263.3 1 2 0 0.0001 8 0 0 0 1.26E+07 8.99E+06 - - - 1.8256 0.9999 221125_WJC_METTL3_EV_vs_WT_F04.10314.10314.2 0.00042 18-Nov R.FVVQNVSAQK[136.11].D "sp|Q92598|HS105_HUMAN,tr|A0A0A0MSM0|A0A0A0MSM0_HUMAN" 2 1126.6226 0.17 44910 10314 2 1126.622602 564.3186 Heat shock protein 105 kDa OS=Homo sapiens OX=9606 GN=HSPH1 PE=1 SV=1 8.75 2191.1 - 3.76E+06 - - - -0.0053 - 2.093 0.5 - 389.6 1 2 0 0 10 0 0 0 9.02E+07 5.35E+08 - - - 4.7957 0.9998 221125_WJC_METTL3_EV_vs_WT_F04.10317.10317.2 0.000116 22-Aug R.DLPDGPDAPADR.Q sp|O95721|SNP29_HUMAN 1 1237.5575 83.25 44911 10317 2 1237.559418 619.786 Synaptosomal-associated protein 29 OS=Homo sapiens OX=9606 GN=SNAP29 PE=1 SV=1 3.77 2191.5 - 1.66E+06 - - - 1.5539 - 1.845 0.559 - 235.1 1 2 0 0.0019 12 0 0 0 5.78E+08 6.94E+06 - - - 4.7807 0.9997 221125_WJC_METTL3_EV_vs_WT_F04.10318.10318.2 0.00329 18-Aug R.WQDAQATLQK[136.11].K "sp|Q13596|SNX1_HUMAN,tr|H0YK42|H0YK42_HUMAN" 2 1195.6077 1.72 44912 10318 2 1195.608783 598.8111 Sorting nexin-1 OS=Homo sapiens OX=9606 GN=SNX1 PE=1 SV=3 5.84 2191.6 - 384502 - - - 0.9167 - 1.699 0.47 - 154.1 1 2 0 0.0011 10 0 0 0 8.99E+06 5.23E+06 - - - 3.9916 0.8457 221125_WJC_METTL3_EV_vs_WT_F04.10319.10319.3 1.38 Sep-40 R.LFEAQGKPELK.G sp|Q9NUG6|PDRG1_HUMAN 1 1258.6921 2.46 44913 10319 3 1258.694228 420.5713 p53 and DNA damage-regulated protein 1 OS=Homo sapiens OX=9606 GN=PDRG1 PE=1 SV=2 6.14 2191.7 - 482724 - - - 1.6605 - 1.528 0.061 - 75.2 1 2 0 0.0021 11 0 0 0 5.98E+07 2.43E+07 - - - 0.4239 0.999 221125_WJC_METTL3_EV_vs_WT_F04.10320.10320.3 0.000708 Nov-40 R.LFEAQGK[136.11]PELK[136.11].G sp|Q9NUG6|PDRG1_HUMAN 1 1274.7205 2.46 44914 10320 3 1274.715681 425.9141 p53 and DNA damage-regulated protein 1 OS=Homo sapiens OX=9606 GN=PDRG1 PE=1 SV=2 6.14 2191.8 - 346436 - - - -3.8102 - 2.085 0.38 - 135.6 1 2 0 -0.0049 11 0 0 0 5.98E+07 2.43E+07 - - - 4.8626 0.9899 221125_WJC_METTL3_EV_vs_WT_F04.10321.10321.2 7.84E-06 24-Jul K.IIDSDEGPEC[160.03]HPP.V sp|Q08554|DSC1_HUMAN 1 1464.6191 - 44915 10321 2 1464.620615 733.3168 Desmocollin-1 OS=Homo sapiens OX=9606 GN=DSC1 PE=1 SV=2 3.91 2192 - 115142 - - - 1.0283 - 1.515 0.632 - 90.8 1 1 0 0.0015 13 0 0 0 - - - - - 4.7747 0.9997 221125_WJC_METTL3_EV_vs_WT_F04.10324.10324.2 0.0333 20-Oct R.LNQLK[136.11]PGLQYK[136.11].L sp|Q12906|ILF3_HUMAN 1 1316.7787 1.27 44916 10324 2 1316.779046 659.3966 Interleukin enhancer-binding factor 3 OS=Homo sapiens OX=9606 GN=ILF3 PE=1 SV=3 9.7 2192.4 - 509496 - - - 0.2461 - 2.243 0.347 - 345.4 1 2 0 0.0003 11 0 0 0 1.53E+07 1.21E+07 - - - 3.7892 0.9636 221125_WJC_METTL3_EV_vs_WT_F04.10325.10325.2 0.0689 14-Jul K.QQFVEYDK[136.11].N "sp|Q14257|RCN2_HUMAN,tr|H0YL43|H0YL43_HUMAN" 2 1063.5066 0.7 44917 10325 2 1063.500712 532.7606 Reticulocalbin-2 OS=Homo sapiens OX=9606 GN=RCN2 PE=1 SV=1 4.37 2192.5 - 324832 - - - -5.5129 - 1.419 0.272 - 185.1 1 2 0 -0.0059 8 0 0 0 6.25E+06 8.87E+06 - - - 2.1036 0.9989 221125_WJC_METTL3_EV_vs_WT_F04.10326.10326.2 0.000402 22-Sep R.VTSEGAGLQLQK.V sp|P10253|LYAG_HUMAN 1 1229.6616 3.82 44918 10326 2 1229.662535 615.8381 Lysosomal alpha-glucosidase OS=Homo sapiens OX=9606 GN=GAA PE=1 SV=4 5.97 2192.6 - 394319 - - - 0.788 - 1.812 0.253 - 245.3 1 2 0 0.001 12 0 0 0 1.03E+07 2.69E+06 - - - 2.4734 0.9999 221125_WJC_METTL3_EV_vs_WT_F04.10332.10332.3 0.00013 Dec-44 K.GIVEFSGK[136.11]PAAR[166.11].K "sp|Q15233|NONO_HUMAN,tr|A0A7I2V535|A0A7I2V535_HUMAN,tr|A0A7I2V4N2|A0A7I2V4N2_HUMAN,tr|A0A7I2V464|A0A7I2V464_HUMAN,tr|A0A7P0MRW0|A0A7P0MRW0_HUMAN,tr|H7C367|H7C367_HUMAN,tr|C9IZL7|C9IZL7_HUMAN,tr|A0A7I2V4J2|A0A7I2V4J2_HUMAN,tr|A0A7I2V5Y7|A0A7I2V5Y7_HUMAN" 9 1248.6945 0.68 44922 10332 3 1248.693857 417.2388 Non-POU domain-containing octamer-binding protein OS=Homo sapiens OX=9606 GN=NONO PE=1 SV=4 8.75 2193.3 - 2.47E+06 - - - -0.5478 - 2.382 0.437 - 162.7 1 2 0 -0.0007 12 0 0 0 3.65E+07 5.39E+07 - - - 5.8177 0.9904 221125_WJC_METTL3_EV_vs_WT_F04.10333.10333.2 0.929 20-Aug R.SDDTAVYYC[160.03]AR.- "sp|P23083|HV102_HUMAN,sp|A0A0C4DH31|HV118_HUMAN" 2 1319.5452 999 44923 10333 2 1319.547092 660.7799 Immunoglobulin heavy variable 1-2 OS=Homo sapiens OX=9606 GN=IGHV1-2 PE=1 SV=2 4.21 2193.5 - 359077 - - - 1.4217 - 1.48 0.12 - 146.8 1 2 0 0.0019 11 0 0 0 2.11E+07 0.00E+00 - - - 0.9873 0.9979 221125_WJC_METTL3_EV_vs_WT_F04.10335.10335.2 0.0529 18-Aug K.GTTIQGLPGK[136.11].N "sp|Q7Z589|EMSY_HUMAN,tr|E9PMC9|E9PMC9_HUMAN" 2 978.5589 0.61 44924 10335 2 978.559645 490.2867 BRCA2-interacting transcriptional repressor EMSY OS=Homo sapiens OX=9606 GN=EMSY PE=1 SV=2 8.75 2193.7 - 474599 - - - 0.7153 - 1.374 0.263 - 202 1 2 0 0.0007 10 0 0 0 1.30E+07 2.13E+07 - - - 1.8702 0.9996 221125_WJC_METTL3_EV_vs_WT_F04.10344.10344.2 4.56E-05 18-Sep K.DYTVTQVPPK.H "sp|Q8N5Z5|KCD17_HUMAN,tr|A0A087WX35|A0A087WX35_HUMAN,tr|H0Y731|H0Y731_HUMAN" 3 1146.5921 2.09 44930 10344 2 1146.592793 574.3033 BTB\POZ domain-containing protein KCTD17 OS=Homo sapiens OX=9606 GN=KCTD17 PE=1 SV=3 5.83 2194.8 - 2.36E+06 - - - 0.6131 - 1.682 0.381 - 260.5 1 2 0 0.0007 10 0 0 0 8.82E+07 4.23E+07 - - - 3.3063 0.9998 221125_WJC_METTL3_EV_vs_WT_F04.10345.10345.2 0.0103 20-Aug K.IDEPLEGSEDR[166.11].L "sp|P61978|HNRPK_HUMAN,tr|S4R359|S4R359_HUMAN" 2 1268.576 1.41 44931 10345 2 1268.575811 635.2953 Heterogeneous nuclear ribonucleoprotein K OS=Homo sapiens OX=9606 GN=HNRNPK PE=1 SV=1 3.83 2194.9 - 1.76E+06 - - - -0.145 - 1.985 0.47 - 280.6 1 2 0 -0.0002 11 0 0 0 1.03E+09 7.32E+08 - - - 4.3671 0.9982 221125_WJC_METTL3_EV_vs_WT_F04.10347.10347.2 0.649 16-Oct R.ATLDEYTTR[166.11].V "sp|Q16656|NRF1_HUMAN,tr|C9JP85|C9JP85_HUMAN" 2 1078.517 1.89 44933 10347 2 1078.517784 540.2658 Nuclear respiratory factor 1 OS=Homo sapiens OX=9606 GN=NRF1 PE=1 SV=1 4.37 2195 - 1.02E+06 - - - 0.7047 - 1.596 0.217 - 274.6 1 2 0 0.0008 9 0 0 0 3.67E+07 1.94E+07 - - - 1.996 1 221125_WJC_METTL3_EV_vs_WT_F04.10348.10348.2 7.55E-09 14/24 F.ILDQTNVSAAAQR[166.11].R "sp|Q00839|HNRPU_HUMAN,tr|A0A1W2PQL0|A0A1W2PQL0_HUMAN,tr|A0A1W2PPL4|A0A1W2PPL4_HUMAN,tr|A0A1W2PQ74|A0A1W2PQ74_HUMAN,tr|Q5RI18|Q5RI18_HUMAN,tr|A0A1W2PP35|A0A1W2PP35_HUMAN,tr|A0A1W2PPS1|A0A1W2PPS1_HUMAN,tr|A0A1W2PRZ7|A0A1W2PRZ7_HUMAN,tr|A0A1W2PPH7|A0A1W2PPH7_HUMAN,tr|A0A1W2PQD4|A0A1W2PQD4_HUMAN,tr|A0A1W2PP34|A0A1W2PP34_HUMAN,tr|A0A1X7SBS1|A0A1X7SBS1_HUMAN" 12 1395.7346 1.07 44934 10348 2 1395.736182 698.8746 Heterogeneous nuclear ribonucleoprotein U OS=Homo sapiens OX=9606 GN=HNRNPU PE=1 SV=6 5.84 2195.1 - 632602 - - - 1.1607 - 2.924 0.601 - 825.5 1 1 0 0.0016 13 0 0 0 2.30E+08 2.14E+08 - - - 6.2332 0.9998 221125_WJC_METTL3_EV_vs_WT_F04.10350.10350.2 0.0022 16-Sep R.EELSDYEER[166.11].L sp|Q15643|TRIPB_HUMAN 1 1178.4967 10.35 44936 10350 2 1178.496558 590.2556 Thyroid receptor-interacting protein 11 OS=Homo sapiens OX=9606 GN=TRIP11 PE=1 SV=3 3.91 2195.4 - 413347 - - - -0.1052 - 2.015 0.431 - 341.4 1 2 0 -0.0001 9 0 0 0 1.05E+08 1.02E+07 - - - 4.2513 1 221125_WJC_METTL3_EV_vs_WT_F04.10351.10351.2 1.33E-08 14/24 F.ILDQTNVSAAAQR.R "sp|Q00839|HNRPU_HUMAN,tr|A0A1W2PQL0|A0A1W2PQL0_HUMAN,tr|A0A1W2PPL4|A0A1W2PPL4_HUMAN,tr|A0A1W2PQ74|A0A1W2PQ74_HUMAN,tr|Q5RI18|Q5RI18_HUMAN,tr|A0A1W2PP35|A0A1W2PP35_HUMAN,tr|A0A1W2PPS1|A0A1W2PPS1_HUMAN,tr|A0A1W2PRZ7|A0A1W2PRZ7_HUMAN,tr|A0A1W2PPH7|A0A1W2PPH7_HUMAN,tr|A0A1W2PQD4|A0A1W2PQD4_HUMAN,tr|A0A1W2PP34|A0A1W2PP34_HUMAN,tr|A0A1X7SBS1|A0A1X7SBS1_HUMAN" 12 1385.7263 1.07 44937 10351 2 1385.730722 693.8704 Heterogeneous nuclear ribonucleoprotein U OS=Homo sapiens OX=9606 GN=HNRNPU PE=1 SV=6 5.84 2195.5 - 381251 - - - 3.1969 - 2.876 0.56 - 693.7 1 1 0 0.0044 13 0 0 0 2.30E+08 2.14E+08 - - - 5.8871 1 221125_WJC_METTL3_EV_vs_WT_F04.10356.10356.2 1.65E-05 15/22 K.TGAEGAVLDEAK.N "sp|Q12840|KIF5A_HUMAN,sp|O60282|KIF5C_HUMAN,sp|P33176|KINH_HUMAN,tr|J3KNA1|J3KNA1_HUMAN,tr|A0A6Q8PEZ8|A0A6Q8PEZ8_HUMAN,tr|A0A0G2JMZ6|A0A0G2JMZ6_HUMAN,tr|A0A6Q8PGJ3|A0A6Q8PGJ3_HUMAN,tr|A0A7I2V3V4|A0A7I2V3V4_HUMAN,tr|A0A7I2V581|A0A7I2V581_HUMAN,tr|A0A7I2V3N5|A0A7I2V3N5_HUMAN,tr|A0A7I2V492|A0A7I2V492_HUMAN,tr|A0A7I2V4K6|A0A7I2V4K6_HUMAN" 12 1159.5721 1.11 44940 10356 2 1159.571277 580.7933 Kinesin heavy chain isoform 5A OS=Homo sapiens OX=9606 GN=KIF5A PE=1 SV=2 4.14 2196.2 - 1.29E+06 - - - -0.6942 - 3.135 0.59 - 795.4 1 2 0 -0.0008 12 0 0 0 9.83E+07 8.87E+07 - - - 6.4049 0.9928 221125_WJC_METTL3_EV_vs_WT_F04.10358.10358.3 3.21E-05 Dec-48 F.ILDQTNVSAAAQR.R "sp|Q00839|HNRPU_HUMAN,tr|A0A1W2PQL0|A0A1W2PQL0_HUMAN,tr|A0A1W2PPL4|A0A1W2PPL4_HUMAN,tr|A0A1W2PQ74|A0A1W2PQ74_HUMAN,tr|Q5RI18|Q5RI18_HUMAN,tr|A0A1W2PP35|A0A1W2PP35_HUMAN,tr|A0A1W2PPS1|A0A1W2PPS1_HUMAN,tr|A0A1W2PRZ7|A0A1W2PRZ7_HUMAN,tr|A0A1W2PPH7|A0A1W2PPH7_HUMAN,tr|A0A1W2PQD4|A0A1W2PQD4_HUMAN,tr|A0A1W2PP34|A0A1W2PP34_HUMAN,tr|A0A1X7SBS1|A0A1X7SBS1_HUMAN" 12 1385.7263 0.88 44942 10358 3 1385.725444 462.916 Heterogeneous nuclear ribonucleoprotein U OS=Homo sapiens OX=9606 GN=HNRNPU PE=1 SV=6 5.84 2196.4 - 441628 - - - -0.612 - 2.09 0.45 - 259.4 1 1 0 -0.0008 13 0 0 0 3.65E+07 4.13E+07 - - - 5.5555 0.9985 221125_WJC_METTL3_EV_vs_WT_F04.10361.10361.3 0.0363 13/48 R.AFVR[166.11]PSGTEDVVR[166.11].V "sp|O95394|AGM1_HUMAN,tr|A0A494C1E2|A0A494C1E2_HUMAN,tr|J3KN95|J3KN95_HUMAN,tr|A0A494C0G1|A0A494C0G1_HUMAN,tr|A0A494C1Q4|A0A494C1Q4_HUMAN,tr|H0Y8I3|H0Y8I3_HUMAN,tr|H0Y987|H0Y987_HUMAN,tr|A0A087WT27|A0A087WT27_HUMAN" 8 1451.7636 0.38 44945 10361 3 1451.764052 484.9285 Phosphoacetylglucosamine mutase OS=Homo sapiens OX=9606 GN=PGM3 PE=1 SV=1 6.12 2196.8 - 326015 - - - 0.3341 - 2.093 0.224 - 217.6 1 2 0 0.0005 13 0 0 0 6.92E+06 1.83E+07 - - - 3.0398 0.9996 221125_WJC_METTL3_EV_vs_WT_F04.10362.10362.2 0.000434 20-Sep K.ESLSTAAEC[160.03]VK.V sp|Q8IYI6|EXOC8_HUMAN 1 1193.5598 1.47 44946 10362 2 1193.560344 597.7872 Exocyst complex component 8 OS=Homo sapiens OX=9606 GN=EXOC8 PE=1 SV=2 4.53 2196.9 - 147594 - - - 0.4533 - 1.495 0.448 - 199.3 1 2 0 0.0005 11 0 0 0 5.94E+06 4.03E+06 - - - 3.4376 0.999 221125_WJC_METTL3_EV_vs_WT_F04.10364.10364.2 0.97 20-Oct K.GGIPNVEGAAK.L sp|Q9BVP2|GNL3_HUMAN 1 1011.5349 0.06 44947 10364 2 1011.534502 506.7747 Guanine nucleotide-binding protein-like 3 OS=Homo sapiens OX=9606 GN=GNL3 PE=1 SV=2 6 2197.1 - 2.27E+06 - - - -0.4024 - 1.433 0.324 - 223.9 1 2 0 -0.0004 11 0 0 0 7.33E+07 1.17E+09 - - - 2.4072 0.996 221125_WJC_METTL3_EV_vs_WT_F04.10367.10367.3 0.134 Oct-36 K.LFK[136.11]PPQPPAR[166.11].M "sp|O15372|EIF3H_HUMAN,tr|B3KS98|B3KS98_HUMAN,tr|A0A087WZK9|A0A087WZK9_HUMAN" 3 1167.6883 2.01 44949 10367 3 1167.686968 390.2367 Eukaryotic translation initiation factor 3 subunit H OS=Homo sapiens OX=9606 GN=EIF3H PE=1 SV=1 11 2197.4 - 2.26E+06 - - - -1.1698 - 1.542 0.235 - 114.8 1 2 0 -0.0014 10 0 0 0 1.14E+08 5.70E+07 - - - 2.4244 0.9998 221125_WJC_METTL3_EV_vs_WT_F04.10368.10368.2 0.00252 16-Oct K.VDYGDISSR.V sp|Q10472|GALT1_HUMAN 1 1010.4669 1.26 44950 10368 2 1010.467242 506.2407 Polypeptide N-acetylgalactosaminyltransferase 1 OS=Homo sapiens OX=9606 GN=GALNT1 PE=1 SV=1 4.21 2197.5 - 2.36E+06 - - - 0.3493 - 1.937 0.435 - 436.7 1 2 0 0.0004 9 0 0 0 4.57E+07 3.62E+07 - - - 4.1665 0.9998 221125_WJC_METTL3_EV_vs_WT_F04.10369.10369.2 0.000248 16-Sep K.VDYGDISSR[166.11].V sp|Q10472|GALT1_HUMAN 1 1020.4752 1.27 44951 10369 2 1020.475752 511.2449 Polypeptide N-acetylgalactosaminyltransferase 1 OS=Homo sapiens OX=9606 GN=GALNT1 PE=1 SV=1 4.21 2197.5 - 2.02E+06 - - - 0.5811 - 1.874 0.452 - 314.2 1 2 0 0.0006 9 0 0 0 4.58E+07 3.62E+07 - - - 4.1963 0.9989 221125_WJC_METTL3_EV_vs_WT_F04.10373.10373.3 0.0208 Aug-44 K.VLEEANQAINPK.L "sp|Q92841|DDX17_HUMAN,tr|A0A5H1ZRQ2|A0A5H1ZRQ2_HUMAN,tr|A0A1X7SBZ2|A0A1X7SBZ2_HUMAN" 3 1324.6987 0.22 44955 10373 3 1324.698413 442.5735 Probable ATP-dependent RNA helicase DDX17 OS=Homo sapiens OX=9606 GN=DDX17 PE=1 SV=2 4.53 2197.9 - 953456 - - - -0.2016 - 1.749 0.28 - 99.2 1 2 0 -0.0003 12 0 0 0 2.40E+07 1.07E+08 - - - 3.2112 0.8639 221125_WJC_METTL3_EV_vs_WT_F04.10374.10374.3 0.026 Sep-44 K.VLEEANQAINPK[136.11].L "sp|Q92841|DDX17_HUMAN,tr|A0A5H1ZRQ2|A0A5H1ZRQ2_HUMAN,tr|A0A1X7SBZ2|A0A1X7SBZ2_HUMAN" 3 1332.7129 0.08 44956 10374 3 1332.711191 445.2449 Probable ATP-dependent RNA helicase DDX17 OS=Homo sapiens OX=9606 GN=DDX17 PE=1 SV=2 4.53 2198 - 684680 - - - -1.2673 - 1.676 0.032 - 90.6 1 2 0 -0.0017 12 0 0 0 8.24E+06 1.09E+08 - - - 0.3277 0.993 221125_WJC_METTL3_EV_vs_WT_F04.10375.10375.2 0.0069 18-Oct K.QAPDNEITIK[136.11].K sp|Q9NX58|LYAR_HUMAN 1 1135.5965 0.92 44957 10375 2 1135.601924 568.8055 Cell growth-regulating nucleolar protein OS=Homo sapiens OX=9606 GN=LYAR PE=1 SV=2 4.37 2198.1 - 671442 - - - 4.8177 - 1.928 0.32 - 411.1 1 2 0 0.0055 10 0 0 0 4.02E+07 4.35E+07 - - - 3.2352 0.9998 221125_WJC_METTL3_EV_vs_WT_F04.10378.10378.2 0.0013 14-Aug K.VGVNGFGR[166.11].L sp|P04406|G3P_HUMAN 1 814.4325 1.24 44958 10378 2 814.432219 408.2235 Glyceraldehyde-3-phosphate dehydrogenase OS=Homo sapiens OX=9606 GN=GAPDH PE=1 SV=3 9.72 2198.5 - 3.43E+06 - - - -0.3524 - 1.811 0.469 - 174.8 1 2 0 -0.0003 8 0 0 0 5.09E+07 4.11E+07 - - - 4.2961 0.9999 221125_WJC_METTL3_EV_vs_WT_F04.10379.10379.2 1.44E-06 18-Sep K.DYTVTQVPPK[136.11].H "sp|Q8N5Z5|KCD17_HUMAN,tr|A0A087WX35|A0A087WX35_HUMAN,tr|H0Y731|H0Y731_HUMAN" 3 1154.6063 2.08 44959 10379 2 1154.606128 578.3104 BTB\POZ domain-containing protein KCTD17 OS=Homo sapiens OX=9606 GN=KCTD17 PE=1 SV=3 5.83 2198.7 - 947704 - - - -0.1403 - 1.961 0.488 - 221.2 1 2 0 -0.0002 10 0 0 0 8.79E+07 4.23E+07 - - - 4.5251 0.9876 221125_WJC_METTL3_EV_vs_WT_F04.10380.10380.3 9.68E-05 Oct-48 F.ILDQTNVSAAAQR[166.11].R "sp|Q00839|HNRPU_HUMAN,tr|A0A1W2PQL0|A0A1W2PQL0_HUMAN,tr|A0A1W2PPL4|A0A1W2PPL4_HUMAN,tr|A0A1W2PQ74|A0A1W2PQ74_HUMAN,tr|Q5RI18|Q5RI18_HUMAN,tr|A0A1W2PP35|A0A1W2PP35_HUMAN,tr|A0A1W2PPS1|A0A1W2PPS1_HUMAN,tr|A0A1W2PRZ7|A0A1W2PRZ7_HUMAN,tr|A0A1W2PPH7|A0A1W2PPH7_HUMAN,tr|A0A1W2PQD4|A0A1W2PQD4_HUMAN,tr|A0A1W2PP34|A0A1W2PP34_HUMAN,tr|A0A1X7SBS1|A0A1X7SBS1_HUMAN" 12 1395.7346 0.85 44960 10380 3 1395.733317 466.2521 Heterogeneous nuclear ribonucleoprotein U OS=Homo sapiens OX=9606 GN=HNRNPU PE=1 SV=6 5.84 2198.7 - 2.12E+06 - - - -0.892 - 2.091 0.402 - 146.5 1 1 0 -0.0012 13 0 0 0 3.65E+07 4.29E+07 - - - 5.0215 0.9986 221125_WJC_METTL3_EV_vs_WT_F04.10386.10386.2 0.0146 22-Oct R.AVLIAGQPGTGK.T "sp|Q9Y230|RUVB2_HUMAN,tr|M0R0Y3|M0R0Y3_HUMAN,tr|M0QXI6|M0QXI6_HUMAN,tr|X6R2L4|X6R2L4_HUMAN" 4 1110.6397 1.17 44966 10386 2 1110.641992 556.3271 RuvB-like 2 OS=Homo sapiens OX=9606 GN=RUVBL2 PE=1 SV=3 8.8 2199.5 - 324404 - - - 2.0565 - 1.866 0.297 - 199.2 1 2 0 0.0023 12 0 0 0 5.58E+06 4.77E+06 - - - 2.8752 0.9996 221125_WJC_METTL3_EV_vs_WT_F04.10388.10388.2 0.0063 22-Nov K.AIVAGDQNVEYK.G "sp|Q13642|FHL1_HUMAN,tr|Q5JXI2|Q5JXI2_HUMAN,tr|A0A0D9SFZ9|A0A0D9SFZ9_HUMAN,tr|A0A0D9SFI6|A0A0D9SFI6_HUMAN,tr|A0A494C0D6|A0A494C0D6_HUMAN,tr|Q5JXH7|Q5JXH7_HUMAN,tr|A0A0D9SGB2|A0A0D9SGB2_HUMAN,tr|Q5JXH9|Q5JXH9_HUMAN,tr|Q5JXI8|Q5JXI8_HUMAN,tr|A0A0D9SFB0|A0A0D9SFB0_HUMAN,tr|Q5JXI0|Q5JXI0_HUMAN,tr|Q5JXH8|Q5JXH8_HUMAN,tr|Q5JXI3|Q5JXI3_HUMAN" 13 1305.6565 0.88 44968 10388 2 1305.654219 653.8355 Four and a half LIM domains protein 1 OS=Homo sapiens OX=9606 GN=FHL1 PE=1 SV=4 4.37 2199.8 - 175542 - - - -1.7325 - 2.376 0.365 - 388.6 1 2 0 -0.0023 12 0 0 0 2.52E+07 2.86E+07 - - - 4.0132 0.9995 221125_WJC_METTL3_EV_vs_WT_F04.10395.10395.2 0.0382 16-Sep R.ILQDSLGGR.T "sp|P52732|KIF11_HUMAN,tr|A0A7I2YQY4|A0A7I2YQY4_HUMAN,tr|A0A7I2V3A9|A0A7I2V3A9_HUMAN,tr|A0A7I2V3V3|A0A7I2V3V3_HUMAN" 4 957.5243 4.2 44973 10395 2 957.524031 479.7694 Kinesin-like protein KIF11 OS=Homo sapiens OX=9606 GN=KIF11 PE=1 SV=2 5.84 2200.6 - 614081 - - - -0.3269 - 1.795 0.313 - 203.3 1 2 0 -0.0003 9 0 0 0 1.71E+07 4.07E+06 - - - 3.0452 0.9989 221125_WJC_METTL3_EV_vs_WT_F04.10396.10396.2 0.0412 14-Sep R.HVILSEIK[136.11].E "sp|Q9BQ70|TCF25_HUMAN,tr|Q9H384|Q9H384_HUMAN,tr|H3BQ53|H3BQ53_HUMAN" 3 945.5739 0.64 44974 10396 2 945.572184 473.7942 Transcription factor 25 OS=Homo sapiens OX=9606 GN=TCF25 PE=1 SV=1 6.75 2200.8 - 555977 - - - -1.7799 - 1.746 0.285 - 200.3 1 2 0 -0.0017 8 0 0 0 7.50E+06 1.17E+07 - - - 2.8264 0.9894 221125_WJC_METTL3_EV_vs_WT_F04.10399.10399.2 0.000414 20-Oct K.VAC[160.03]AEEWQESR.T sp|O75663|TIPRL_HUMAN 1 1363.5827 0.69 44977 10399 2 1363.591055 682.7986 TIP41-like protein OS=Homo sapiens OX=9606 GN=TIPRL PE=1 SV=2 4.25 2201.1 - 422200 - - - 6.1536 - 1.624 0.467 - 239.8 1 2 0 0.0084 11 0 0 0 3.17E+06 4.62E+06 - - - 3.7994 0.9998 221125_WJC_METTL3_EV_vs_WT_F04.10400.10400.2 0.000257 14-Oct K.HIAVFPC[160.03]K[136.11].L "sp|O60841|IF2P_HUMAN,tr|A0A087WUT6|A0A087WUT6_HUMAN" 2 978.5201 0.3 44978 10400 2 978.519119 490.2673 Eukaryotic translation initiation factor 5B OS=Homo sapiens OX=9606 GN=EIF5B PE=1 SV=4 8.23 2201.3 - 340380 - - - -0.9596 - 1.86 0.419 - 438.6 1 2 0 -0.0009 8 0 0 0 3.21E+06 1.08E+07 - - - 4.0071 0.9996 221125_WJC_METTL3_EV_vs_WT_F04.10406.10406.3 0.00405 Nov-40 K.ELDTDR[166.11]PSLVR[166.11].R "sp|Q9NRA8|4ET_HUMAN,tr|B1AKL5|B1AKL5_HUMAN,tr|B1AKL4|B1AKL4_HUMAN" 3 1319.6948 1.22 44982 10406 3 1319.69324 440.9055 Eukaryotic translation initiation factor 4E transporter OS=Homo sapiens OX=9606 GN=EIF4ENIF1 PE=1 SV=2 4.56 2201.9 - 2.84E+06 - - - -1.1965 - 1.887 0.332 - 208.5 1 2 0 -0.0016 11 0 0 0 2.33E+08 1.91E+08 - - - 4.0449 0.9996 221125_WJC_METTL3_EV_vs_WT_F04.10407.10407.3 0.0152 Sep-48 K.LGHPDTLNQGEFK.E sp|P06702|S10A9_HUMAN 1 1454.7154 32.38 44983 10407 3 1454.715181 485.9124 Protein S100-A9 OS=Homo sapiens OX=9606 GN=S100A9 PE=1 SV=1 5.32 2202 - 2.24E+06 - - - -0.1457 - 1.813 0.341 - 98.8 1 2 0 -0.0002 13 0 0 0 4.27E+07 1.32E+06 - - - 3.9549 0.9999 221125_WJC_METTL3_EV_vs_WT_F04.10408.10408.2 0.0225 22-Dec K.AIVAGDQNVEYK[136.11].G "sp|Q13642|FHL1_HUMAN,tr|Q5JXI2|Q5JXI2_HUMAN,tr|A0A0D9SFZ9|A0A0D9SFZ9_HUMAN,tr|A0A0D9SFI6|A0A0D9SFI6_HUMAN,tr|A0A494C0D6|A0A494C0D6_HUMAN,tr|Q5JXH7|Q5JXH7_HUMAN,tr|A0A0D9SGB2|A0A0D9SGB2_HUMAN,tr|Q5JXH9|Q5JXH9_HUMAN,tr|Q5JXI8|Q5JXI8_HUMAN,tr|A0A0D9SFB0|A0A0D9SFB0_HUMAN,tr|Q5JXI0|Q5JXI0_HUMAN,tr|Q5JXH8|Q5JXH8_HUMAN,tr|Q5JXI3|Q5JXI3_HUMAN" 13 1313.6707 0.88 44984 10408 2 1313.669322 657.8426 Four and a half LIM domains protein 1 OS=Homo sapiens OX=9606 GN=FHL1 PE=1 SV=4 4.37 2202.1 - 1.49E+06 - - - -1.0345 - 2.575 0.465 - 455.7 1 2 0 -0.0014 12 0 0 0 2.52E+07 2.86E+07 - - - 4.9638 0.9949 221125_WJC_METTL3_EV_vs_WT_F04.10412.10412.2 0.161 20-Aug R.QLPPNGDPNFK.L "sp|Q92945|FUBP2_HUMAN,tr|M0R3J3|M0R3J3_HUMAN,tr|M0R0C6|M0R0C6_HUMAN,tr|A0A087WTP3|A0A087WTP3_HUMAN" 4 1225.6091 0.83 44988 10412 2 1225.607709 613.8118 Far upstream element-binding protein 2 OS=Homo sapiens OX=9606 GN=KHSRP PE=1 SV=4 5.84 2202.6 - 373743 - - - -1.1651 - 1.345 0.193 - 82.8 1 2 0 -0.0014 11 0 0 0 3.05E+06 3.68E+06 - - - 1.2679 0.9997 221125_WJC_METTL3_EV_vs_WT_F04.10413.10413.2 0.00223 20-Sep K.VAC[160.03]AEEWQESR[166.11].T sp|O75663|TIPRL_HUMAN 1 1373.5909 0.69 44989 10413 2 1373.58763 687.8027 TIP41-like protein OS=Homo sapiens OX=9606 GN=TIPRL PE=1 SV=2 4.25 2202.8 - 372176 - - - -2.4054 - 2.153 0.575 - 294.7 1 2 0 -0.0033 11 0 0 0 3.17E+06 4.62E+06 - - - 5.3615 0.9973 221125_WJC_METTL3_EV_vs_WT_F04.10414.10414.2 0.488 18-Jul K.ISLNTPPGTK.V "sp|Q9H7E2|TDRD3_HUMAN,tr|B1AMN9|B1AMN9_HUMAN,tr|F2Z2Y2|F2Z2Y2_HUMAN" 3 1026.571 1.33 44990 10414 2 1026.570228 514.2928 Tudor domain-containing protein 3 OS=Homo sapiens OX=9606 GN=TDRD3 PE=1 SV=1 8.75 2202.9 - 397542 - - - -0.7131 - 1.619 0.168 - 100.9 1 2 0 -0.0007 10 0 0 0 1.14E+07 8.56E+06 - - - 1.6265 0.9991 221125_WJC_METTL3_EV_vs_WT_F04.10417.10417.3 0.00282 Oct-40 K.ELDTDRPSLVR.R "sp|Q9NRA8|4ET_HUMAN,tr|B1AKL5|B1AKL5_HUMAN,tr|B1AKL4|B1AKL4_HUMAN" 3 1299.6783 1.22 44991 10417 3 1299.677059 434.2334 Eukaryotic translation initiation factor 4E transporter OS=Homo sapiens OX=9606 GN=EIF4ENIF1 PE=1 SV=2 4.56 2203.3 - 6.74E+06 - - - -0.9387 - 1.5 0.331 - 179.5 1 2 0 -0.0012 11 0 0 0 2.33E+08 1.91E+08 - - - 3.3818 0.9975 221125_WJC_METTL3_EV_vs_WT_F04.10418.10418.2 0.0242 14-Jul K.ISYAQYEK.Y "sp|Q08188|TGM3_HUMAN,tr|A0A494C0J7|A0A494C0J7_HUMAN" 2 1000.4866 26.5 44992 10418 2 1000.484562 501.2506 Protein-glutamine gamma-glutamyltransferase E OS=Homo sapiens OX=9606 GN=TGM3 PE=1 SV=4 6 2203.4 - 999138 - - - -1.999 - 1.204 0.358 - 107.8 1 2 0 -0.002 8 0 0 0 1.19E+07 4.49E+05 - - - 2.2445 0.9895 221125_WJC_METTL3_EV_vs_WT_F04.10419.10419.3 0.0225 Oct-40 R.GVLHTFSPSPK.L sp|Q86YP4|P66A_HUMAN 1 1168.6241 1.67 44993 10419 3 1168.622102 390.5486 Transcriptional repressor p66-alpha OS=Homo sapiens OX=9606 GN=GATAD2A PE=1 SV=1 8.76 2203.4 - 3.43E+06 - - - -1.6738 - 1.69 0.189 - 99.3 2 2 0 -0.002 11 0 0 0 5.85E+07 3.50E+07 - - - 1.998 0.9998 221125_WJC_METTL3_EV_vs_WT_F04.10423.10423.2 0.00241 20-Nov R.LEQDLQQMQAK[136.11].V sp|P12270|TPR_HUMAN 1 1338.6693 1.33 44997 10423 2 1338.66927 670.3419 Nucleoprotein TPR OS=Homo sapiens OX=9606 GN=TPR PE=1 SV=3 4.37 2203.9 - 603394 - - - -0.0232 - 2.064 0.394 - 326.8 1 2 0 0 11 0 0 0 1.01E+07 7.58E+06 - - - 3.9114 0.9998 221125_WJC_METTL3_EV_vs_WT_F04.10429.10429.2 0.000583 18-Aug K.NLDDGIDDER.L "sp|Q9H361|PABP3_HUMAN,sp|P11940|PABP1_HUMAN,tr|A0A7I2YQE4|A0A7I2YQE4_HUMAN,tr|A0A7I2V649|A0A7I2V649_HUMAN,tr|H0YAR2|H0YAR2_HUMAN,tr|E7ERJ7|E7ERJ7_HUMAN,tr|A0A7I2YQ88|A0A7I2YQ88_HUMAN,tr|A0A087WTT1|A0A087WTT1_HUMAN,tr|H0YAP2|H0YAP2_HUMAN,tr|A0A7I2V4N4|A0A7I2V4N4_HUMAN,tr|E7EQV3|E7EQV3_HUMAN" 11 1160.4946 1.5 45001 10429 2 1160.493415 581.2546 Polyadenylate-binding protein 3 OS=Homo sapiens OX=9606 GN=PABPC3 PE=1 SV=2 3.71 2204.6 - 1.29E+07 - - - -0.9866 - 1.741 0.514 - 223.8 1 2 0 -0.0011 10 0 0 0 6.78E+08 4.53E+08 - - - 4.3847 0.9669 221125_WJC_METTL3_EV_vs_WT_F04.10430.10430.2 0.0993 18-Aug K.QAPDNEITIK.K sp|Q9NX58|LYAR_HUMAN 1 1127.5823 0.71 45002 10430 2 1127.578298 564.7984 Cell growth-regulating nucleolar protein OS=Homo sapiens OX=9606 GN=LYAR PE=1 SV=2 4.37 2204.7 - 1.01E+06 - - - -3.5075 - 1.258 0.188 - 185.5 1 2 0 -0.004 10 0 0 0 2.53E+07 3.58E+07 - - - 1.069 0.9987 221125_WJC_METTL3_EV_vs_WT_F04.10432.10432.3 0.00933 Nov-40 K.YTELQLEAAK[136.11]R[166.11].G "sp|Q5T8P6|RBM26_HUMAN,tr|E2PSN0|E2PSN0_HUMAN,tr|A0A087X0H9|A0A087X0H9_HUMAN" 3 1338.7262 10.74 45004 10432 3 1338.723063 447.2494 RNA-binding protein 26 OS=Homo sapiens OX=9606 GN=RBM26 PE=1 SV=3 6.14 2204.9 - 836856 - - - -2.3694 - 1.618 0.344 - 136.8 1 2 0 -0.0032 11 0 0 0 1.24E+08 1.15E+07 - - - 3.7414 0.9999 221125_WJC_METTL3_EV_vs_WT_F04.10435.10435.3 0.000206 13/48 K.AANVLLSEHGEVK.L "sp|Q9Y6E0|STK24_HUMAN,tr|B4DR80|B4DR80_HUMAN,tr|H0Y630|H0Y630_HUMAN" 3 1365.7252 0.88 45007 10435 3 1365.726081 456.249 Serine\threonine-protein kinase 24 OS=Homo sapiens OX=9606 GN=STK24 PE=1 SV=1 5.4 2205.3 - 408686 - - - 0.6238 - 2.581 0.403 - 245.4 1 2 0 0.0009 13 0 0 0 1.19E+07 1.36E+07 - - - 5.6036 0.9998 221125_WJC_METTL3_EV_vs_WT_F04.10436.10436.2 0.000225 26-Aug M.PLPEPSEQEGESVK[136.11].A "sp|Q4VC44|FWCH1_HUMAN,sp|Q96CP2|FWCH2_HUMAN,tr|I3L0R3|I3L0R3_HUMAN,tr|I3L231|I3L231_HUMAN,tr|I3L1Y9|I3L1Y9_HUMAN,tr|I3L4I0|I3L4I0_HUMAN" 6 1532.745 0.17 45008 10436 2 1532.7465 767.3798 FLYWCH-type zinc finger-containing protein 1 OS=Homo sapiens OX=9606 GN=FLYWCH1 PE=1 SV=2 4.09 2205.4 - 309808 - - - 0.9995 - 1.651 0.563 - 103.6 1 2 0 0.0015 14 0 0 0 1.38E+06 8.29E+06 - - - 4.457 0.9538 221125_WJC_METTL3_EV_vs_WT_F04.10441.10441.3 0.0948 Dec-40 K.VATAYR[166.11]PPALR[166.11].N "sp|Q9BY44|EIF2A_HUMAN,tr|F8WAE5|F8WAE5_HUMAN,tr|H7C5R5|H7C5R5_HUMAN" 3 1233.7097 0.23 45011 10441 3 1233.707573 412.2438 Eukaryotic translation initiation factor 2A OS=Homo sapiens OX=9606 GN=EIF2A PE=1 SV=3 10.83 2206.1 - 667093 - - - -1.7087 - 1.717 0.094 - 242.5 1 2 0 -0.0021 11 0 0 0 4.29E+06 1.87E+07 - - - 1.1231 0.9992 221125_WJC_METTL3_EV_vs_WT_F04.10442.10442.2 0.14 14-Oct K.KIQLLEAK.F "sp|Q86U86|PB1_HUMAN,tr|E7EVG2|E7EVG2_HUMAN" 2 941.591 1.4 45012 10442 2 941.590589 471.8028 Protein polybromo-1 OS=Homo sapiens OX=9606 GN=PBRM1 PE=1 SV=1 8.59 2206.2 - 798480 - - - -0.4014 - 1.738 0.256 - 356.7 1 2 0 -0.0004 8 0 0 0 1.46E+07 1.04E+07 - - - 2.5987 0.9537 221125_WJC_METTL3_EV_vs_WT_F04.10443.10443.2 0.178 14-Sep K.LMQLVDHR[166.11].G "sp|Q92841|DDX17_HUMAN,tr|A0A5H1ZRQ2|A0A5H1ZRQ2_HUMAN,tr|A0A1X7SBZ2|A0A1X7SBZ2_HUMAN" 3 1020.5414 1.25 45013 10443 2 1020.546971 511.278 Probable ATP-dependent RNA helicase DDX17 OS=Homo sapiens OX=9606 GN=DDX17 PE=1 SV=2 6.74 2206.3 - 537223 - - - 5.454 - 1.484 0.224 - 359.1 1 2 0 0.0056 8 0 0 0 1.06E+07 8.46E+06 - - - 1.8842 0.9999 221125_WJC_METTL3_EV_vs_WT_F04.10444.10444.2 2.42E-05 22-Nov K.VGSVEEFQGQER[166.11].S "sp|Q9HCE1|MOV10_HUMAN,tr|Q5JR04|Q5JR04_HUMAN" 2 1373.6451 1.03 45014 10444 2 1373.644248 687.8298 Helicase MOV-10 OS=Homo sapiens OX=9606 GN=MOV10 PE=1 SV=2 4.25 2206.4 - 445913 - - - -0.6042 - 2.211 0.476 - 455 1 2 0 -0.0008 12 0 0 0 9.43E+06 9.14E+06 - - - 4.6442 0.9995 221125_WJC_METTL3_EV_vs_WT_F04.10445.10445.2 0.00288 22-Jul R.VIQVAAGSSNLK.R sp|P05091|ALDH2_HUMAN 1 1185.6717 0.28 45015 10445 2 1185.671424 593.8431 "Aldehyde dehydrogenase, mitochondrial OS=Homo sapiens OX=9606 GN=ALDH2 PE=1 SV=2" 8.72 2206.6 - 299127 - - - -0.264 - 1.665 0.364 - 116.6 1 2 0 -0.0003 12 0 0 0 2.82E+06 9.92E+06 - - - 3.0708 0.9956 221125_WJC_METTL3_EV_vs_WT_F04.10446.10446.2 0.00181 24-Jul K.LGHPDTLNQGEFK.E sp|P06702|S10A9_HUMAN 1 1454.7154 999 45016 10446 2 1454.7143 728.365 Protein S100-A9 OS=Homo sapiens OX=9606 GN=S100A9 PE=1 SV=1 5.32 2206.7 - 156387 - - - -0.7513 - 1.402 0.183 - 94 1 2 0 -0.0011 13 0 0 0 2.69E+06 0.00E+00 - - - 1.2595 0.9996 221125_WJC_METTL3_EV_vs_WT_F04.10452.10452.2 0.0003 22-Sep K.VGSVEEFQGQER.S "sp|Q9HCE1|MOV10_HUMAN,tr|Q5JR04|Q5JR04_HUMAN" 2 1363.6368 1.03 45019 10452 2 1363.639957 682.8257 Helicase MOV-10 OS=Homo sapiens OX=9606 GN=MOV10 PE=1 SV=2 4.25 2207.4 - 734828 - - - 2.3093 - 2.233 0.476 - 339.5 1 2 0 0.0031 12 0 0 0 9.43E+06 9.14E+06 - - - 4.6695 0.9922 221125_WJC_METTL3_EV_vs_WT_F04.10453.10453.2 0.045 18-Sep R.DGTISEDTIR[166.11].A "sp|Q99816|TS101_HUMAN,tr|F5H442|F5H442_HUMAN" 2 1115.5334 2.43 45020 10453 2 1115.528413 558.774 Tumor susceptibility gene 101 protein OS=Homo sapiens OX=9606 GN=TSG101 PE=1 SV=2 4.03 2207.5 - 909962 - - - -4.4723 - 1.775 0.299 - 303 1 2 0 -0.005 10 0 0 0 4.43E+07 1.82E+07 - - - 2.8495 0.9992 221125_WJC_METTL3_EV_vs_WT_F04.10456.10456.2 0.0224 14-Aug R.YDFQNPSR.M "sp|Q8TAQ2|SMRC2_HUMAN,tr|F8VXC8|F8VXC8_HUMAN" 2 1025.4567 4.74 45023 10456 2 1025.457221 513.7356 SWI\SNF complex subunit SMARCC2 OS=Homo sapiens OX=9606 GN=SMARCC2 PE=1 SV=1 5.84 2207.8 - 414511 - - - 0.548 - 1.576 0.308 - 263.3 1 2 0 0.0006 8 0 0 0 1.77E+07 3.74E+06 - - - 2.6876 0.9767 221125_WJC_METTL3_EV_vs_WT_F04.10459.10459.2 1.71E-05 12-Sep V.PNLHVMK[136.11].A "sp|Q9NQ39|RS10L_HUMAN,sp|P46783|RS10_HUMAN,tr|A0A2R8Y6L3|A0A2R8Y6L3_HUMAN,tr|F6U211|F6U211_HUMAN,tr|A0A1W2PQS6|A0A1W2PQS6_HUMAN,tr|A0A2R8YFH6|A0A2R8YFH6_HUMAN,tr|A0A2R8Y7H1|A0A2R8Y7H1_HUMAN,tr|S4R435|S4R435_HUMAN" 8 845.4673 1.17 45024 10459 2 845.466324 423.7409 Putative 40S ribosomal protein S10-like OS=Homo sapiens OX=9606 GN=RPS10P5 PE=5 SV=1 9.18 2208.2 - 1.64E+06 - - - -1.1473 - 2.092 0.292 - 260.6 1 1 0 -0.001 7 0 0 0 7.52E+08 6.41E+08 - - - 3.5362 0.9987 221125_WJC_METTL3_EV_vs_WT_F04.10461.10461.2 0.0194 18-Nov R.SGFSSVSVSR.S sp|P02538|K2C6A_HUMAN 1 1011.4985 2739.09 45026 10461 2 1011.495158 506.7565 "Keratin, type II cytoskeletal 6A OS=Homo sapiens OX=9606 GN=KRT6A PE=1 SV=3" 9.47 2208.5 - 708905 - - - -3.3267 - 1.982 0.407 - 304 1 2 0 -0.0034 10 0 0 0 5.47E+09 2.00E+06 - - - 3.9556 0.9998 221125_WJC_METTL3_EV_vs_WT_F04.10462.10462.2 0.000438 16-Sep R.QGSFQGGFR.S "sp|P0C0L4|CO4A_HUMAN,sp|P0C0L5|CO4B_HUMAN,tr|A0A140TA32|A0A140TA32_HUMAN,tr|A0A140TA44|A0A140TA44_HUMAN,tr|A0A0G2JL54|A0A0G2JL54_HUMAN,tr|A0A3B3ISA6|A0A3B3ISA6_HUMAN,tr|A0A140TA29|A0A140TA29_HUMAN,tr|A0A0G2JPR0|A0A0G2JPR0_HUMAN,tr|A0A3B3ISD7|A0A3B3ISD7_HUMAN,tr|A0A140TA49|A0A140TA49_HUMAN,tr|F5GXS0|F5GXS0_HUMAN" 11 982.4621 6.41 45027 10462 2 982.461761 492.2383 Complement C4-A OS=Homo sapiens OX=9606 GN=C4A PE=1 SV=2 9.75 2208.6 - 603222 - - - -0.3227 - 1.914 0.403 - 260.8 1 2 0 -0.0003 9 0 0 0 7.50E+06 1.17E+06 - - - 3.8956 0.9993 221125_WJC_METTL3_EV_vs_WT_F04.10464.10464.3 0.0151 Nov-36 K.LFKPPQPPAR.M "sp|O15372|EIF3H_HUMAN,tr|B3KS98|B3KS98_HUMAN,tr|A0A087WZK9|A0A087WZK9_HUMAN" 3 1149.6659 1.99 45028 10464 3 1149.663949 384.2292 Eukaryotic translation initiation factor 3 subunit H OS=Homo sapiens OX=9606 GN=EIF3H PE=1 SV=1 11 2208.8 - 4.69E+06 - - - -1.6657 - 2.153 0.276 - 189 1 2 0 -0.0019 10 0 0 0 1.52E+08 7.65E+07 - - - 3.8562 0.9998 221125_WJC_METTL3_EV_vs_WT_F04.10467.10467.2 0.0928 18-Oct R.NIEMTQEDVR.L "sp|O75643|U520_HUMAN,tr|A0A494C1A5|A0A494C1A5_HUMAN" 2 1233.566 0.07 45030 10467 2 1233.566318 617.7903 U5 small nuclear ribonucleoprotein 200 kDa helicase OS=Homo sapiens OX=9606 GN=SNRNP200 PE=1 SV=2 4.14 2209.1 - 2.88E+06 - - - 0.2975 - 1.962 0.416 - 342.5 1 2 0 0.0004 10 0 0 0 7.81E+07 1.15E+09 - - - 3.9947 0.9736 221125_WJC_METTL3_EV_vs_WT_F04.10468.10468.2 0.0148 12-Aug V.PNLHVMK.A "sp|Q9NQ39|RS10L_HUMAN,sp|P46783|RS10_HUMAN,tr|A0A2R8Y6L3|A0A2R8Y6L3_HUMAN,tr|F6U211|F6U211_HUMAN,tr|A0A1W2PQS6|A0A1W2PQS6_HUMAN,tr|A0A2R8YFH6|A0A2R8YFH6_HUMAN,tr|A0A2R8Y7H1|A0A2R8Y7H1_HUMAN,tr|S4R435|S4R435_HUMAN" 8 837.4531 1.18 45031 10468 2 837.451964 419.7338 Putative 40S ribosomal protein S10-like OS=Homo sapiens OX=9606 GN=RPS10P5 PE=5 SV=1 9.18 2209.2 - 2.20E+06 - - - -1.3493 - 1.755 0.364 - 192.5 1 1 0 -0.0011 7 0 0 0 7.70E+08 6.54E+08 - - - 3.5114 1 221125_WJC_METTL3_EV_vs_WT_F04.10469.10469.2 6.17E-06 13/24 S.SYGAQAASSYGVR.A sp|Q96PK6|RBM14_HUMAN 1 1315.6157 2.31 45032 10469 2 1315.61368 658.8151 RNA-binding protein 14 OS=Homo sapiens OX=9606 GN=RBM14 PE=1 SV=2 8.31 2209.3 - 1.07E+06 - - - -1.5194 - 2.475 0.629 - 616 1 1 0 -0.002 13 0 0 0 1.14E+07 4.95E+06 - - - 6.0121 0.9304 221125_WJC_METTL3_EV_vs_WT_F04.10470.10470.2 1.8 12-Jun R.DVNC[160.03]PFK[136.11].L "sp|Q9Y224|RTRAF_HUMAN,tr|G3V4C6|G3V4C6_HUMAN,tr|H0YJB9|H0YJB9_HUMAN" 3 886.4098 1.11 45033 10470 2 886.408508 444.2122 "RNA transcription, translation and transport factor protein OS=Homo sapiens OX=9606 GN=RTRAF PE=1 SV=1" 5.83 2209.4 - 937002 - - - -1.5016 - 0.901 0.123 - 125.9 1 2 0 -0.0013 7 0 0 0 1.89E+07 1.70E+07 - - - -0.3813 1 221125_WJC_METTL3_EV_vs_WT_F04.10471.10471.2 3.31E-06 15/20 K.GAIDHYVTPVK[136.11].A "sp|Q9NX20|RM16_HUMAN,tr|E9PI14|E9PI14_HUMAN" 2 1206.6488 1.24 45034 10471 2 1206.649348 604.3317 "39S ribosomal protein L16, mitochondrial OS=Homo sapiens OX=9606 GN=MRPL16 PE=1 SV=1" 6.74 2209.5 - 712739 - - - 0.4351 - 3.005 0.509 - 836.2 1 2 0 0.0005 11 0 0 0 3.92E+07 3.16E+07 - - - 5.7768 1 221125_WJC_METTL3_EV_vs_WT_F04.10472.10472.2 2.62E-07 20-Dec K.NGETELC[160.03]MEGR[166.11].G "sp|O95433|AHSA1_HUMAN,tr|H0YJU2|H0YJU2_HUMAN,tr|G3V438|G3V438_HUMAN" 3 1304.5365 1.26 45035 10472 2 1304.535141 653.2755 Activator of 90 kDa heat shock protein ATPase homolog 1 OS=Homo sapiens OX=9606 GN=AHSA1 PE=1 SV=1 4.25 2209.7 - 537956 - - - -1.008 - 2.786 0.682 - 918.3 1 2 0 -0.0013 11 0 0 0 1.80E+07 1.43E+07 - - - 6.8496 0.9999 221125_WJC_METTL3_EV_vs_WT_F04.10473.10473.2 4.58E-05 13/20 K.GAIDHYVTPVK.A "sp|Q9NX20|RM16_HUMAN,tr|E9PI14|E9PI14_HUMAN" 2 1198.6346 1.26 45036 10473 2 1198.634371 600.3246 "39S ribosomal protein L16, mitochondrial OS=Homo sapiens OX=9606 GN=MRPL16 PE=1 SV=1" 6.74 2209.8 - 536252 - - - -0.2102 - 2.496 0.423 - 446.2 1 2 0 -0.0003 11 0 0 0 3.98E+07 3.16E+07 - - - 4.6396 0.9994 221125_WJC_METTL3_EV_vs_WT_F04.10478.10478.2 0.000458 18-Aug K.NQAETIALEK.E "sp|Q13948|CASP_HUMAN,sp|P39880|CUX1_HUMAN,tr|A0A2R8Y8D0|A0A2R8Y8D0_HUMAN,tr|A0A2R8Y852|A0A2R8Y852_HUMAN,tr|A0A2R8YDI1|A0A2R8YDI1_HUMAN" 5 1115.5823 1.48 45039 10478 2 1115.580369 558.7984 Protein CASP OS=Homo sapiens OX=9606 GN=CUX1 PE=1 SV=2 4.53 2210.4 - 2.15E+06 - - - -1.6888 - 1.772 0.384 - 248.5 1 2 0 -0.0019 10 0 0 0 2.21E+08 1.49E+08 - - - 3.4736 0.9995 221125_WJC_METTL3_EV_vs_WT_F04.10479.10479.3 0.0013 Dec-32 R.C[160.03]RPFNLAER.K "sp|P52732|KIF11_HUMAN,tr|A0A7I2YQY4|A0A7I2YQY4_HUMAN,tr|A0A7I2V3V3|A0A7I2V3V3_HUMAN" 3 1161.5713 4.98 45040 10479 3 1161.568862 388.1977 Kinesin-like protein KIF11 OS=Homo sapiens OX=9606 GN=KIF11 PE=1 SV=2 8.25 2210.5 - 2.83E+06 - - - -2.1092 - 2.02 0.337 - 273 1 2 0 -0.0024 9 0 0 0 1.16E+08 2.33E+07 - - - 4.4155 0.9998 221125_WJC_METTL3_EV_vs_WT_F04.10480.10480.2 2.01E-05 18-Nov K.NQAETIALEK[136.11].E "sp|Q13948|CASP_HUMAN,sp|P39880|CUX1_HUMAN,tr|A0A2R8Y8D0|A0A2R8Y8D0_HUMAN,tr|A0A2R8Y852|A0A2R8Y852_HUMAN,tr|A0A2R8YDI1|A0A2R8YDI1_HUMAN" 5 1123.5965 1.48 45041 10480 2 1123.59513 562.8055 Protein CASP OS=Homo sapiens OX=9606 GN=CUX1 PE=1 SV=2 4.53 2210.6 - 1.83E+06 - - - -1.1775 - 2.22 0.491 - 530.6 1 2 0 -0.0013 10 0 0 0 2.20E+08 1.49E+08 - - - 4.8932 1 221125_WJC_METTL3_EV_vs_WT_F04.10481.10481.2 9.46E-07 20-Oct K.NGETELC[160.03]MEGR.G "sp|O95433|AHSA1_HUMAN,tr|H0YJU2|H0YJU2_HUMAN,tr|G3V438|G3V438_HUMAN" 3 1294.5282 1.26 45042 10481 2 1294.524295 648.2714 Activator of 90 kDa heat shock protein ATPase homolog 1 OS=Homo sapiens OX=9606 GN=AHSA1 PE=1 SV=1 4.25 2210.7 - 1.13E+06 - - - -3.0057 - 2.569 0.659 - 464.2 1 2 0 -0.0039 11 0 0 0 1.80E+07 1.43E+07 - - - 6.4596 1 221125_WJC_METTL3_EV_vs_WT_F04.10484.10484.2 1.01E-11 19/28 R.C[160.03]TGGEVGATSALAPK.L sp|P30050|RL12_HUMAN 1 1417.6871 1.5 45045 10484 2 1417.686133 709.8508 60S ribosomal protein L12 OS=Homo sapiens OX=9606 GN=RPL12 PE=1 SV=1 5.99 2211.1 - 435461 - - - -0.7026 - 3.525 0.712 - 1367.8 1 2 0 -0.001 15 0 0 0 1.39E+08 9.26E+07 - - - 7.397 0.9884 221125_WJC_METTL3_EV_vs_WT_F04.10485.10485.2 4.41E-07 13/26 L.AVNAAQDSTDLVAK[136.11].L "sp|P17987|TCPA_HUMAN,tr|F5H282|F5H282_HUMAN,tr|E7EQR6|E7EQR6_HUMAN" 3 1409.7242 0.38 45046 10485 2 1409.721202 705.8694 T-complex protein 1 subunit alpha OS=Homo sapiens OX=9606 GN=TCP1 PE=1 SV=1 4.21 2211.2 - 260418 - - - -2.1075 - 2.749 0.551 - 621.1 1 1 0 -0.003 14 0 0 0 2.63E+06 6.86E+06 - - - 5.6474 0.9999 221125_WJC_METTL3_EV_vs_WT_F04.10489.10489.3 0.000412 Nov-40 K.GAIDHYVTPVK.A "sp|Q9NX20|RM16_HUMAN,tr|E9PI14|E9PI14_HUMAN" 2 1198.6346 0.96 45048 10489 3 1198.634017 400.5522 "39S ribosomal protein L16, mitochondrial OS=Homo sapiens OX=9606 GN=MRPL16 PE=1 SV=1" 6.74 2211.7 - 5.84E+06 - - - -0.5056 - 2.134 0.438 - 162.5 1 2 0 -0.0006 11 0 0 0 1.23E+08 1.28E+08 - - - 5.5764 0.9998 221125_WJC_METTL3_EV_vs_WT_F04.10491.10491.2 0.00994 18-Oct R.NIEMTQEDVR[166.11].L "sp|O75643|U520_HUMAN,tr|A0A494C1A5|A0A494C1A5_HUMAN" 2 1243.5742 0.03 45050 10491 2 1243.572341 622.7944 U5 small nuclear ribonucleoprotein 200 kDa helicase OS=Homo sapiens OX=9606 GN=SNRNP200 PE=1 SV=2 4.14 2211.9 - 2.35E+06 - - - -1.5118 - 1.952 0.486 - 359.1 1 2 0 -0.0019 10 0 0 0 8.14E+07 2.44E+09 - - - 4.497 0.9999 221125_WJC_METTL3_EV_vs_WT_F04.10492.10492.2 2.73E-06 18-Sep R.SGVSLAALK[136.11]K[136.11].A "sp|P10412|H14_HUMAN,sp|P16403|H12_HUMAN,sp|P16402|H13_HUMAN" 3 988.6252 0.66 45051 10492 2 988.624549 495.3199 Histone H1.4 OS=Homo sapiens OX=9606 GN=H1-4 PE=1 SV=2 10 2211.9 - 1.94E+06 - - - -0.6393 - 2.111 0.505 - 237.3 1 2 0 -0.0006 10 0 0 0 2.12E+07 3.21E+07 - - - 4.8563 0.9998 221125_WJC_METTL3_EV_vs_WT_F04.10494.10494.2 0.000622 18-Nov R.SGVSLAALKK.A "sp|P10412|H14_HUMAN,sp|P16403|H12_HUMAN,sp|P16402|H13_HUMAN" 3 972.5968 0.66 45053 10494 2 972.596897 487.3057 Histone H1.4 OS=Homo sapiens OX=9606 GN=H1-4 PE=1 SV=2 10 2212.2 - 913881 - - - 0.1193 - 2.003 0.407 - 394.3 1 2 0 0.0001 10 0 0 0 2.11E+07 3.21E+07 - - - 3.986 0.9993 221125_WJC_METTL3_EV_vs_WT_F04.10496.10496.2 0.0685 14-Oct K.QGIGHLLR.G sp|Q8N0X7|SPART_HUMAN 1 892.5243 1.28 45055 10496 2 892.524154 447.2694 Spartin OS=Homo sapiens OX=9606 GN=SPART PE=1 SV=1 9.76 2212.4 - 600211 - - - -0.1468 - 1.672 0.29 - 422 1 2 0 -0.0001 8 0 0 0 1.31E+07 1.03E+07 - - - 2.7332 1 221125_WJC_METTL3_EV_vs_WT_F04.10497.10497.2 3.51E-09 16/28 R.C[160.03]TGGEVGATSALAPK[136.11].L sp|P30050|RL12_HUMAN 1 1425.7013 1.5 45056 10497 2 1425.693434 713.8579 60S ribosomal protein L12 OS=Homo sapiens OX=9606 GN=RPL12 PE=1 SV=1 5.99 2212.6 - 553716 - - - -5.5376 - 2.849 0.658 - 771.1 1 2 0 -0.0079 15 0 0 0 1.39E+08 9.26E+07 - - - 6.4725 0.999 221125_WJC_METTL3_EV_vs_WT_F04.10498.10498.2 0.0829 16-Nov K.KLLEATELK.G "sp|Q13813|SPTN1_HUMAN,tr|A0A0D9SF54|A0A0D9SF54_HUMAN,tr|A0A0D9SGF6|A0A0D9SGF6_HUMAN" 3 1043.6227 1.46 45057 10498 2 1043.623036 522.8186 "Spectrin alpha chain, non-erythrocytic 1 OS=Homo sapiens OX=9606 GN=SPTAN1 PE=1 SV=3" 6.14 2212.7 - 426826 - - - 0.3593 - 1.867 0.211 - 447.4 1 2 0 0.0004 9 0 0 0 7.09E+06 4.85E+06 - - - 2.4056 0.9935 221125_WJC_METTL3_EV_vs_WT_F04.10503.10503.2 0.0434 18-Aug K.EIGGLTQVNK[136.11].N "sp|O14497|ARI1A_HUMAN,tr|H0Y488|H0Y488_HUMAN,tr|A0A1B0GTU5|A0A1B0GTU5_HUMAN,tr|A0A087WUV6|A0A087WUV6_HUMAN" 4 1065.591 9.13 45060 10503 2 1065.592475 533.8028 AT-rich interactive domain-containing protein 1A OS=Homo sapiens OX=9606 GN=ARID1A PE=1 SV=3 6.1 2213.2 - 893992 - - - 1.4086 - 1.477 0.154 - 187.2 1 2 0 0.0015 10 0 0 0 1.95E+08 2.14E+07 - - - 1.2666 0.9881 221125_WJC_METTL3_EV_vs_WT_F04.10505.10505.3 1.04 Dec-40 R.YISSQIER[166.11]PIR[166.11].L sp|O75643|U520_HUMAN 1 1380.7628 1.44 45062 10505 3 1380.761432 461.2616 U5 small nuclear ribonucleoprotein 200 kDa helicase OS=Homo sapiens OX=9606 GN=SNRNP200 PE=1 SV=2 8.75 2213.4 - 2.06E+06 - - - -1.019 - 1.332 0.211 - 188.3 1 2 0 -0.0014 11 0 0 0 8.41E+07 5.82E+07 - - - 1.7065 0.9864 221125_WJC_METTL3_EV_vs_WT_F04.10508.10508.2 1.26 12-Jun K.SSFSITR[166.11].E "sp|Q9Y2W1|TR150_HUMAN,tr|A0A3B3ITZ9|A0A3B3ITZ9_HUMAN" 2 806.4162 2.38 45063 10508 2 806.415158 404.2154 Thyroid hormone receptor-associated protein 3 OS=Homo sapiens OX=9606 GN=THRAP3 PE=1 SV=2 9.47 2213.8 - 1.15E+07 - - - -1.2773 - 1.144 0.156 - 172.1 1 2 0 -0.001 7 0 0 0 3.69E+09 1.55E+09 - - - 0.6192 0.9984 221125_WJC_METTL3_EV_vs_WT_F04.10510.10510.2 0.00623 14-Jul K.ATFDAISK[136.11].T "sp|P15880|RS2_HUMAN,tr|E9PQD7|E9PQD7_HUMAN,tr|H0YEN5|H0YEN5_HUMAN" 3 859.4531 1.35 45065 10510 2 859.452308 430.7338 40S ribosomal protein S2 OS=Homo sapiens OX=9606 GN=RPS2 PE=1 SV=2 5.88 2214.1 - 477726 - - - -0.9017 - 1.424 0.267 - 164.5 1 2 0 -0.0008 8 0 0 0 3.25E+07 2.40E+07 - - - 2.0789 0.881 221125_WJC_METTL3_EV_vs_WT_F04.10512.10512.2 1.01 20-May R.YISSQIERPIR.L sp|O75643|U520_HUMAN 1 1360.7463 2.72 45067 10512 2 1360.743791 681.3804 U5 small nuclear ribonucleoprotein 200 kDa helicase OS=Homo sapiens OX=9606 GN=SNRNP200 PE=1 SV=2 8.75 2214.3 - 255458 - - - -1.8431 - 1.126 0.022 - 28.4 2 2 0 -0.0025 11 0 0 0 5.50E+06 2.02E+06 - - - -0.6107 0.9965 221125_WJC_METTL3_EV_vs_WT_F04.10516.10516.2 0.113 12-Jun K.SSFSITR.E "sp|Q9Y2W1|TR150_HUMAN,tr|A0A3B3ITZ9|A0A3B3ITZ9_HUMAN" 2 796.4079 2.38 45069 10516 2 796.407355 399.2112 Thyroid hormone receptor-associated protein 3 OS=Homo sapiens OX=9606 GN=THRAP3 PE=1 SV=2 9.47 2214.8 - 3.79E+07 - - - -0.7069 - 1.301 0.209 - 169.4 1 2 0 -0.0006 7 0 0 0 3.69E+09 1.55E+09 - - - 1.4182 0.9996 221125_WJC_METTL3_EV_vs_WT_F04.10517.10517.2 0.00203 16-Aug K.NVPNLHVMK.A "sp|Q9NQ39|RS10L_HUMAN,sp|P46783|RS10_HUMAN,tr|A0A2R8Y6L3|A0A2R8Y6L3_HUMAN,tr|F6U211|F6U211_HUMAN,tr|A0A1W2PQS6|A0A1W2PQS6_HUMAN,tr|A0A2R8YFH6|A0A2R8YFH6_HUMAN,tr|A0A2R8Y7H1|A0A2R8Y7H1_HUMAN,tr|S4R435|S4R435_HUMAN" 8 1050.5644 1.09 45070 10517 2 1050.563424 526.2895 Putative 40S ribosomal protein S10-like OS=Homo sapiens OX=9606 GN=RPS10P5 PE=5 SV=1 8.76 2214.9 - 7.60E+06 - - - -0.9623 - 1.481 0.45 - 119.5 1 2 0 -0.001 9 0 0 0 3.99E+08 3.67E+08 - - - 3.5005 0.9986 221125_WJC_METTL3_EV_vs_WT_F04.10518.10518.2 0.022 18-Aug R.QYVDSDGPLK[136.11].Q "sp|O75529|TAF5L_HUMAN,tr|Q5TDI7|Q5TDI7_HUMAN" 2 1128.5543 1.2 45071 10518 2 1128.552813 565.2844 TAF5-like RNA polymerase II p300\CBP-associated factor-associated factor 65 kDa subunit 5L OS=Homo sapiens OX=9606 GN=TAF5L PE=1 SV=1 4.21 2214.9 - 752988 - - - -1.2769 - 1.569 0.277 - 176.8 1 2 0 -0.0014 10 0 0 0 7.85E+07 6.52E+07 - - - 2.3438 0.9982 221125_WJC_METTL3_EV_vs_WT_F04.10519.10519.2 0.0113 14-Jun K.ATFDAISK.T "sp|P15880|RS2_HUMAN,tr|E9PQD7|E9PQD7_HUMAN,tr|H0YEN5|H0YEN5_HUMAN" 3 851.4389 1.08 45072 10519 2 851.438166 426.7267 40S ribosomal protein S2 OS=Homo sapiens OX=9606 GN=RPS2 PE=1 SV=2 5.88 2215.1 - 624910 - - - -0.8421 - 1.325 0.285 - 129.3 1 2 0 -0.0007 8 0 0 0 2.54E+07 2.35E+07 - - - 1.9945 0.9999 221125_WJC_METTL3_EV_vs_WT_F04.10525.10525.2 3.67E-05 20-Dec K.IDEPLEGSEDR.L "sp|P61978|HNRPK_HUMAN,tr|S4R359|S4R359_HUMAN" 2 1258.5677 1.41 45076 10525 2 1258.567109 630.2911 Heterogeneous nuclear ribonucleoprotein K OS=Homo sapiens OX=9606 GN=HNRNPK PE=1 SV=1 3.83 2215.9 - 5.08E+06 - - - -0.4894 - 2.31 0.587 - 733.6 1 2 0 -0.0006 11 0 0 0 1.03E+09 7.32E+08 - - - 5.6413 0.9999 221125_WJC_METTL3_EV_vs_WT_F04.10526.10526.3 0.00365 15/44 K.YAVTTGDHGIIR[166.11].T "sp|P53621|COPA_HUMAN,tr|A0A3B3ISC6|A0A3B3ISC6_HUMAN,tr|A0A3B3IS84|A0A3B3IS84_HUMAN,tr|A0A3B3IU89|A0A3B3IU89_HUMAN,tr|A0A3B3IT15|A0A3B3IT15_HUMAN" 5 1311.6811 0.27 45077 10526 3 1311.681581 438.2343 Coatomer subunit alpha OS=Homo sapiens OX=9606 GN=COPA PE=1 SV=2 6.74 2215.9 - 1.51E+06 - - - 0.3896 - 2.563 0.424 - 250.2 1 2 0 0.0005 12 0 0 0 2.42E+07 9.07E+07 - - - 5.8758 0.9985 221125_WJC_METTL3_EV_vs_WT_F04.10530.10530.2 0.00599 14-Aug K.TDSYFNPK[136.11].M sp|Q7Z2T5|TRM1L_HUMAN 1 978.4538 1.09 45081 10530 2 978.450902 490.2342 TRMT1-like protein OS=Homo sapiens OX=9606 GN=TRMT1L PE=1 SV=2 5.5 2216.4 - 529184 - - - -2.9741 - 1.628 0.395 - 385.1 1 2 0 -0.0029 8 0 0 0 1.56E+07 1.43E+07 - - - 3.4274 0.9998 221125_WJC_METTL3_EV_vs_WT_F04.10531.10531.2 5.77E-05 16-Aug K.DGDMTAFNK[136.11].L "sp|Q9NRA8|4ET_HUMAN,tr|B1AKL4|B1AKL4_HUMAN,tr|B0QYZ7|B0QYZ7_HUMAN" 3 1005.4317 1.18 45082 10531 2 1005.429866 503.7231 Eukaryotic translation initiation factor 4E transporter OS=Homo sapiens OX=9606 GN=EIF4ENIF1 PE=1 SV=2 4.21 2216.5 - 442377 - - - -1.8201 - 1.902 0.554 - 377.9 1 2 0 -0.0018 9 0 0 0 5.82E+07 4.94E+07 - - - 4.9922 0.9999 221125_WJC_METTL3_EV_vs_WT_F04.10536.10536.2 4.62E-06 22-Dec K.AVENSSTAIGIR[166.11].C sp|P25788|PSA3_HUMAN 1 1226.6494 0.74 45085 10536 2 1226.649902 614.332 Proteasome subunit alpha type-3 OS=Homo sapiens OX=9606 GN=PSMA3 PE=1 SV=2 6.05 2217.1 - 1.81E+06 - - - 0.3807 - 2.464 0.526 - 499.8 1 2 0 0.0005 12 0 0 0 6.91E+07 9.31E+07 - - - 5.2986 0.9997 221125_WJC_METTL3_EV_vs_WT_F04.10537.10537.2 0.000228 16-Jul K.DGDMTAFNK.L "sp|Q9NRA8|4ET_HUMAN,tr|B1AKL4|B1AKL4_HUMAN,tr|B0QYZ7|B0QYZ7_HUMAN" 3 997.4175 1.18 45086 10537 2 997.416102 499.716 Eukaryotic translation initiation factor 4E transporter OS=Homo sapiens OX=9606 GN=EIF4ENIF1 PE=1 SV=2 4.21 2217.2 - 1.14E+06 - - - -1.3976 - 1.66 0.462 - 291.4 1 2 0 -0.0014 9 0 0 0 5.82E+07 4.93E+07 - - - 3.9191 0.9998 221125_WJC_METTL3_EV_vs_WT_F04.10538.10538.2 1.08E-05 14/24 K.TVNQQTMAAPVVK[136.11].E "sp|Q9Y520|PRC2C_HUMAN,tr|E7EPN9|E7EPN9_HUMAN" 2 1393.7479 1.11 45087 10538 2 1393.746116 697.8812 Protein PRRC2C OS=Homo sapiens OX=9606 GN=PRRC2C PE=1 SV=4 8.41 2217.4 - 737880 - - - -1.2692 - 2.518 0.472 - 649.3 1 2 0 -0.0018 13 0 0 0 3.61E+07 3.26E+07 - - - 4.8967 0.9998 221125_WJC_METTL3_EV_vs_WT_F04.10539.10539.2 8.26E-08 16-Oct R.C[160.03]NVIITQPR.R "sp|Q7L2E3|DHX30_HUMAN,tr|H7BXY3|H7BXY3_HUMAN" 2 1099.5808 1.24 45088 10539 2 1099.583024 550.7977 ATP-dependent RNA helicase DHX30 OS=Homo sapiens OX=9606 GN=DHX30 PE=1 SV=1 8.25 2217.5 - 616766 - - - 2.0099 - 2.159 0.592 - 610.9 1 2 0 0.0022 9 0 0 0 1.48E+07 1.19E+07 - - - 5.6394 0.8755 221125_WJC_METTL3_EV_vs_WT_F04.10542.10542.2 0.0965 26-Jun R.HLLPNSGAAATSAA.M sp|Q9BQ04|RBM4B_HUMAN 1 1279.6521 - 45091 10542 2 1279.650383 640.8333 RNA-binding protein 4B OS=Homo sapiens OX=9606 GN=RBM4B PE=1 SV=1 6.74 2217.9 - 227184 - - - -1.3136 - 1.309 0.299 - 93.1 1 1 0 -0.0017 14 0 0 0 - - - - - 1.9246 0.9992 221125_WJC_METTL3_EV_vs_WT_F04.10544.10544.2 0.00684 16-Aug R.RPSTFGIPR.L "sp|P78347|GTF2I_HUMAN,tr|A0A494C1K3|A0A494C1K3_HUMAN" 2 1029.572 1.53 45092 10544 2 1029.570429 515.7933 General transcription factor II-I OS=Homo sapiens OX=9606 GN=GTF2I PE=1 SV=2 12 2218.1 - 2.51E+06 - - - -1.4899 - 1.698 0.328 - 121.5 1 2 0 -0.0015 9 0 0 0 3.47E+08 2.27E+08 - - - 2.9949 0.9998 221125_WJC_METTL3_EV_vs_WT_F04.10546.10546.3 0.00752 Dec-36 K.VEHVVSVLEK[136.11].K sp|Q9NYU2|UGGG1_HUMAN 1 1145.6536 0.07 45093 10546 3 1145.649808 382.8918 UDP-glucose:glycoprotein glucosyltransferase 1 OS=Homo sapiens OX=9606 GN=UGGT1 PE=1 SV=3 5.4 2218.3 - 595371 - - - -3.2872 - 2.567 0.456 - 255.6 1 2 0 -0.0038 10 0 0 0 8.29E+05 1.27E+07 - - - 6.3761 0.9983 221125_WJC_METTL3_EV_vs_WT_F04.10548.10548.3 0.00133 13/40 K.LRAESEVPIVK.T "sp|Q96L14|C170L_HUMAN,sp|Q5SW79|CE170_HUMAN,tr|H0Y2V6|H0Y2V6_HUMAN,tr|E7EMW0|E7EMW0_HUMAN,tr|H0Y4T4|H0Y4T4_HUMAN,tr|E7EWM2|E7EWM2_HUMAN" 6 1239.7187 1.26 45094 10548 3 1239.716056 414.2468 Cep170-like protein OS=Homo sapiens OX=9606 GN=CEP170P1 PE=5 SV=2 6.14 2218.5 - 1.45E+06 - - - -2.1223 - 2.453 0.318 - 342.5 1 2 1 -0.0026 11 0 0 0 3.54E+07 2.81E+07 - - - 4.6338 0.9998 221125_WJC_METTL3_EV_vs_WT_F04.10552.10552.2 4.23E-06 22-Nov K.AVENSSTAIGIR.C sp|P25788|PSA3_HUMAN 1 1216.6412 0.74 45097 10552 2 1216.63867 609.3279 Proteasome subunit alpha type-3 OS=Homo sapiens OX=9606 GN=PSMA3 PE=1 SV=2 6.05 2218.9 - 2.21E+06 - - - -2.0507 - 2.362 0.571 - 370 1 2 0 -0.0025 12 0 0 0 6.91E+07 9.31E+07 - - - 5.5191 0.9999 221125_WJC_METTL3_EV_vs_WT_F04.10553.10553.3 0.193 19/44 R.LEELDADK[136.11]AEMR[166.11].A "sp|Q9UG63|ABCF2_HUMAN,tr|C9JZV3|C9JZV3_HUMAN,tr|C9JHK9|C9JHK9_HUMAN" 3 1436.6936 0.74 45098 10553 3 1436.691759 479.9051 ATP-binding cassette sub-family F member 2 OS=Homo sapiens OX=9606 GN=ABCF2 PE=1 SV=2 4.18 2219 - 1.07E+06 - - - -1.2919 - 2.947 0.472 - 771 1 2 1 -0.0019 12 0 0 0 1.87E+07 2.54E+07 - - - 6.7976 0.7871 221125_WJC_METTL3_EV_vs_WT_F04.10554.10554.2 0.00282 26-Sep A.LSPTTAPAVSSVSK.Q "sp|Q8WXI9|P66B_HUMAN,tr|A0A0U1RRM1|A0A0U1RRM1_HUMAN,tr|A0A0U1RR30|A0A0U1RR30_HUMAN" 3 1343.7296 1.85 45099 10554 2 1343.725097 672.8721 Transcriptional repressor p66-beta OS=Homo sapiens OX=9606 GN=GATAD2B PE=1 SV=1 8.75 2219.1 - 425284 - - - -3.3854 - 1.812 0.283 - 172.3 1 1 0 -0.0045 14 0 0 0 9.03E+06 4.89E+06 - - - 2.6215 0.9514 221125_WJC_METTL3_EV_vs_WT_F04.10557.10557.2 0.255 14-Aug K.GK[136.11]VEYLLK[136.11].W "sp|P83916|CBX1_HUMAN,tr|K7ELA4|K7ELA4_HUMAN,tr|J3KS05|J3KS05_HUMAN,tr|B5MD17|B5MD17_HUMAN,tr|C9JWS9|C9JWS9_HUMAN" 5 964.5928 0.85 45100 10557 2 964.590305 483.3037 Chromobox protein homolog 1 OS=Homo sapiens OX=9606 GN=CBX1 PE=1 SV=1 8.5 2219.5 - 1.54E+06 - - - -2.6052 - 1.761 0.184 - 183.6 1 2 1 -0.0025 8 0 0 0 2.30E+07 2.70E+07 - - - 2.1059 0.9995 221125_WJC_METTL3_EV_vs_WT_F04.10559.10559.2 0.0968 14-Oct R.HIWITAAK.L sp|O94906|PRP6_HUMAN 1 938.5338 2.48 45101 10559 2 938.533132 470.2742 Pre-mRNA-processing factor 6 OS=Homo sapiens OX=9606 GN=PRPF6 PE=1 SV=1 8.76 2219.7 - 1.00E+06 - - - -0.6979 - 1.855 0.3 - 411.6 1 2 0 -0.0007 8 0 0 0 6.13E+07 2.47E+07 - - - 3.1201 0.9988 221125_WJC_METTL3_EV_vs_WT_F04.10560.10560.2 0.00192 18-Oct R.SGEIVQEYDR[166.11].H "sp|O60508|PRP17_HUMAN,tr|Q5SRN1|Q5SRN1_HUMAN" 2 1204.56 1.31 45102 10560 2 1204.555708 603.2873 Pre-mRNA-processing factor 17 OS=Homo sapiens OX=9606 GN=CDC40 PE=1 SV=1 4.14 2219.9 - 580760 - - - -3.5224 - 2.335 0.374 - 483.8 1 2 0 -0.0042 10 0 0 0 2.38E+07 1.82E+07 - - - 4.1691 0.9998 221125_WJC_METTL3_EV_vs_WT_F04.10565.10565.2 2.54E-05 18-Dec R.SGEIVQEYDR.H "sp|O60508|PRP17_HUMAN,tr|Q5SRN1|Q5SRN1_HUMAN" 2 1194.5517 1.34 45107 10565 2 1194.552954 598.2831 Pre-mRNA-processing factor 17 OS=Homo sapiens OX=9606 GN=CDC40 PE=1 SV=1 4.14 2220.4 - 579140 - - - 1.0657 - 2.447 0.465 - 704.9 1 2 0 0.0013 10 0 0 0 2.38E+07 1.77E+07 - - - 4.9729 0.9981 221125_WJC_METTL3_EV_vs_WT_F04.10566.10566.2 0.00721 18-Jun R.RLNDFASTVR.L "sp|P20674|COX5A_HUMAN,tr|H3BNX8|H3BNX8_HUMAN,tr|H3BV69|H3BV69_HUMAN,tr|H3BRM5|H3BRM5_HUMAN" 4 1177.6204 0.91 45108 10566 2 1177.621472 589.8175 "Cytochrome c oxidase subunit 5A, mitochondrial OS=Homo sapiens OX=9606 GN=COX5A PE=1 SV=2" 9.6 2220.5 - 426416 - - - 0.9358 - 1.749 0.215 - 66.4 2 2 0 0.0011 10 0 0 0 3.21E+07 3.53E+07 - - - 2.0546 0.9994 221125_WJC_METTL3_EV_vs_WT_F04.10570.10570.2 0.000757 18-Oct R.SSQIDQAIVK[136.11].S "sp|Q9UPN3|MACF1_HUMAN,tr|H3BQK9|H3BQK9_HUMAN,tr|A0A7P0MQR8|A0A7P0MQR8_HUMAN,tr|H0Y390|H0Y390_HUMAN,tr|H3BPE1|H3BPE1_HUMAN,tr|A0A590UJG2|A0A590UJG2_HUMAN" 6 1095.6015 5.96 45110 10570 2 1095.600408 548.808 "Microtubule-actin cross-linking factor 1, isoforms 1\2\3\5 OS=Homo sapiens OX=9606 GN=MACF1 PE=1 SV=4" 5.55 2221 - 481999 - - - -1.0323 - 1.571 0.365 - 207.8 1 2 0 -0.0011 10 0 0 0 3.60E+07 6.04E+06 - - - 2.9974 0.9994 221125_WJC_METTL3_EV_vs_WT_F04.10575.10575.2 0.00949 16-Sep R.TLSDYNIQK.E "sp|P62979|RS27A_HUMAN,sp|P0CG48|UBC_HUMAN,sp|P0CG48|UBC_HUMAN,sp|P0CG48|UBC_HUMAN,sp|P0CG48|UBC_HUMAN,sp|P0CG48|UBC_HUMAN,sp|P0CG48|UBC_HUMAN,sp|P0CG48|UBC_HUMAN,sp|P0CG48|UBC_HUMAN,sp|P0CG48|UBC_HUMAN,sp|P0CG47|UBB_HUMAN,sp|P0CG47|UBB_HUMAN,sp|P0CG47|UBB_HUMAN,sp|P62987|RL40_HUMAN,tr|F5H388|F5H388_HUMAN,tr|F5H388|F5H388_HUMAN,tr|F5GYU3|F5GYU3_HUMAN,tr|B4DV12|B4DV12_HUMAN,tr|B4DV12|B4DV12_HUMAN,tr|Q5PY61|Q5PY61_HUMAN,tr|Q5PY61|Q5PY61_HUMAN,tr|Q5PY61|Q5PY61_HUMAN,tr|F5H2Z3|F5H2Z3_HUMAN,tr|M0R2S1|M0R2S1_HUMAN,tr|J3QS39|J3QS39_HUMAN,tr|J3QTR3|J3QTR3_HUMAN,tr|Q96C32|Q96C32_HUMAN,tr|Q96C32|Q96C32_HUMAN,tr|Q96C32|Q96C32_HUMAN,tr|Q96C32|Q96C32_HUMAN,tr|M0R1V7|M0R1V7_HUMAN,tr|F5H747|F5H747_HUMAN,tr|F5H747|F5H747_HUMAN,tr|F5GXK7|F5GXK7_HUMAN,tr|F5GXK7|F5GXK7_HUMAN,tr|M0R1M6|M0R1M6_HUMAN,tr|F5H6Q2|F5H6Q2_HUMAN,tr|J3QKN0|J3QKN0_HUMAN,tr|J3QKN0|J3QKN0_HUMAN,tr|F5H265|F5H265_HUMAN,tr|F5H265|F5H265_HUMAN,tr|A0A2R8Y422|A0A2R8Y422_HUMAN" 42 1080.5451 0.61 45113 10575 2 1080.544991 541.2798 Ubiquitin-40S ribosomal protein S27a OS=Homo sapiens OX=9606 GN=RPS27A PE=1 SV=2 5.5 2221.7 - 1.24E+06 - - - -0.137 - 1.481 0.369 - 179.3 1 2 0 -0.0001 9 0 0 0 1.09E+09 1.79E+09 - - - 2.9025 0.9997 221125_WJC_METTL3_EV_vs_WT_F04.10577.10577.2 0.0186 16-Sep R.TLSDYNIQK[136.11].E "sp|P62979|RS27A_HUMAN,sp|P0CG48|UBC_HUMAN,sp|P0CG48|UBC_HUMAN,sp|P0CG48|UBC_HUMAN,sp|P0CG48|UBC_HUMAN,sp|P0CG48|UBC_HUMAN,sp|P0CG48|UBC_HUMAN,sp|P0CG48|UBC_HUMAN,sp|P0CG48|UBC_HUMAN,sp|P0CG48|UBC_HUMAN,sp|P0CG47|UBB_HUMAN,sp|P0CG47|UBB_HUMAN,sp|P0CG47|UBB_HUMAN,sp|P62987|RL40_HUMAN,tr|F5H388|F5H388_HUMAN,tr|F5H388|F5H388_HUMAN,tr|F5GYU3|F5GYU3_HUMAN,tr|B4DV12|B4DV12_HUMAN,tr|B4DV12|B4DV12_HUMAN,tr|Q5PY61|Q5PY61_HUMAN,tr|Q5PY61|Q5PY61_HUMAN,tr|Q5PY61|Q5PY61_HUMAN,tr|F5H2Z3|F5H2Z3_HUMAN,tr|M0R2S1|M0R2S1_HUMAN,tr|J3QS39|J3QS39_HUMAN,tr|J3QTR3|J3QTR3_HUMAN,tr|Q96C32|Q96C32_HUMAN,tr|Q96C32|Q96C32_HUMAN,tr|Q96C32|Q96C32_HUMAN,tr|Q96C32|Q96C32_HUMAN,tr|M0R1V7|M0R1V7_HUMAN,tr|F5H747|F5H747_HUMAN,tr|F5H747|F5H747_HUMAN,tr|F5GXK7|F5GXK7_HUMAN,tr|F5GXK7|F5GXK7_HUMAN,tr|M0R1M6|M0R1M6_HUMAN,tr|F5H6Q2|F5H6Q2_HUMAN,tr|J3QKN0|J3QKN0_HUMAN,tr|J3QKN0|J3QKN0_HUMAN,tr|F5H265|F5H265_HUMAN,tr|F5H265|F5H265_HUMAN,tr|A0A2R8Y422|A0A2R8Y422_HUMAN" 42 1088.5593 0.61 45115 10577 2 1088.558797 545.2869 Ubiquitin-40S ribosomal protein S27a OS=Homo sapiens OX=9606 GN=RPS27A PE=1 SV=2 5.5 2221.8 - 2.13E+06 - - - -0.4979 - 1.635 0.415 - 178.6 1 2 0 -0.0005 9 0 0 0 1.09E+09 1.79E+09 - - - 3.5284 0.9997 221125_WJC_METTL3_EV_vs_WT_F04.10578.10578.3 0.0175 Dec-40 K.LGAPQTHLGLK[136.11].N "sp|Q96C19|EFHD2_HUMAN,sp|Q9BUP0|EFHD1_HUMAN,tr|Q8WYH2|Q8WYH2_HUMAN,tr|A0A087X1Z2|A0A087X1Z2_HUMAN,tr|H0Y4Y4|H0Y4Y4_HUMAN,tr|C9JTV4|C9JTV4_HUMAN" 6 1141.6699 0.001 45116 10578 3 1141.669256 381.5639 EF-hand domain-containing protein D2 OS=Homo sapiens OX=9606 GN=EFHD2 PE=1 SV=1 8.76 2222 - 708341 - - - -0.558 - 2.018 0.336 - 103.7 1 2 0 -0.0006 11 0 0 0 0.00E+00 2.71E+07 - - - 4.2805 0.9996 221125_WJC_METTL3_EV_vs_WT_F04.10580.10580.2 0.0746 18-Oct R.RLSSEVEALR.R sp|P15924|DESP_HUMAN 1 1158.6357 126.18 45118 10580 2 1158.634885 580.3251 Desmoplakin OS=Homo sapiens OX=9606 GN=DSP PE=1 SV=3 6.14 2222.2 - 559776 - - - -0.6913 - 2.079 0.293 - 127.4 1 2 0 -0.0008 10 0 0 0 1.76E+07 1.39E+05 - - - 3.2478 0.9999 221125_WJC_METTL3_EV_vs_WT_F04.10584.10584.2 0.000228 22-Dec K.VDVTEQPGLSGR[166.11].F "sp|Q9H3N1|TMX1_HUMAN,tr|G3V448|G3V448_HUMAN" 2 1266.6444 1.51 45120 10584 2 1266.642966 634.3295 Thioredoxin-related transmembrane protein 1 OS=Homo sapiens OX=9606 GN=TMX1 PE=1 SV=1 4.37 2222.8 - 1.56E+06 - - - -1.0927 - 2.576 0.479 - 235.2 1 2 0 -0.0014 12 0 0 0 1.23E+08 8.13E+07 - - - 5.0682 0.9996 221125_WJC_METTL3_EV_vs_WT_F04.10586.10586.2 0.000559 14-Oct K.HGLYLPTR[166.11].V "sp|P49327|FAS_HUMAN,tr|A0A0U1RQF0|A0A0U1RQF0_HUMAN" 2 965.5322 0.76 45122 10586 2 965.53365 483.7734 Fatty acid synthase OS=Homo sapiens OX=9606 GN=FASN PE=1 SV=3 8.75 2223 - 1.08E+06 - - - 1.481 - 1.852 0.407 - 295.2 1 2 0 0.0014 8 0 0 0 3.74E+07 4.89E+07 - - - 3.9053 0.9447 221125_WJC_METTL3_EV_vs_WT_F04.10589.10589.2 0.00639 20-Aug R.TPYVTTTVSAH.S "sp|Q9BSJ2|GCP2_HUMAN,tr|A0A804HLH6|A0A804HLH6_HUMAN,tr|A0A804HJH7|A0A804HJH7_HUMAN,tr|F2Z2B9|F2Z2B9_HUMAN,tr|R4GMM4|R4GMM4_HUMAN,tr|A0A804HK74|A0A804HK74_HUMAN,tr|A0A804HL95|A0A804HL95_HUMAN,tr|A0A804HJ08|A0A804HJ08_HUMAN,tr|A0A804HJQ4|A0A804HJQ4_HUMAN,tr|A0A804HJS9|A0A804HJS9_HUMAN,tr|A0A804HL05|A0A804HL05_HUMAN,tr|A0A804HI27|A0A804HI27_HUMAN" 12 1175.5823 - 45125 10589 2 1175.583484 588.7984 Gamma-tubulin complex component 2 OS=Homo sapiens OX=9606 GN=TUBGCP2 PE=1 SV=2 6.4 2223.4 - 299796 - - - 1.0471 - 1.591 0.321 - 89.2 1 1 0 0.0012 11 0 0 0 - - - - - 2.6677 0.9996 221125_WJC_METTL3_EV_vs_WT_F04.10593.10593.2 0.000417 20-Sep R.LLQQSGAQQFR.M "sp|Q96QD9|UIF_HUMAN,tr|H9KVD5|H9KVD5_HUMAN,tr|H9KVD1|H9KVD1_HUMAN" 3 1274.6731 2.06 45127 10593 2 1274.671655 638.3438 UAP56-interacting factor OS=Homo sapiens OX=9606 GN=FYTTD1 PE=1 SV=3 9.75 2223.9 - 952577 - - - -1.1603 - 1.809 0.395 - 250.2 1 2 0 -0.0015 11 0 0 0 1.83E+07 8.90E+06 - - - 3.5616 0.996 221125_WJC_METTL3_EV_vs_WT_F04.10594.10594.2 0.0114 16-Jul K.HGPLALVDK[136.11].L "sp|Q06210|GFPT1_HUMAN,tr|A0A6I8PRN4|A0A6I8PRN4_HUMAN" 2 956.5535 7.64 45128 10594 2 956.556041 479.284 Glutamine--fructose-6-phosphate aminotransferase [isomerizing] 1 OS=Homo sapiens OX=9606 GN=GFPT1 PE=1 SV=3 6.74 2223.9 - 1.03E+06 - - - 2.692 - 1.34 0.326 - 121.1 1 2 0 0.0026 9 0 0 0 1.76E+08 2.30E+07 - - - 2.2947 0.9999 221125_WJC_METTL3_EV_vs_WT_F04.10595.10595.2 0.00203 20-Nov R.LNQDQLDAVSK[136.11].Y "sp|Q14444|CAPR1_HUMAN,tr|G3V153|G3V153_HUMAN,tr|E9PLA9|E9PLA9_HUMAN" 3 1237.6394 0.97 45129 10595 2 1237.639681 619.827 Caprin-1 OS=Homo sapiens OX=9606 GN=CAPRIN1 PE=1 SV=2 4.21 2224.1 - 628902 - - - 0.2424 - 2.315 0.442 - 381 1 2 0 0.0003 11 0 0 0 5.06E+08 5.23E+08 - - - 4.5763 0.9896 221125_WJC_METTL3_EV_vs_WT_F04.10600.10600.2 4.96E-05 20-Sep R.AYTPPEDLQSR.L sp|Q8N5N7|RM50_HUMAN 1 1275.6095 1.64 45131 10600 2 1275.604149 638.812 "39S ribosomal protein L50, mitochondrial OS=Homo sapiens OX=9606 GN=MRPL50 PE=1 SV=2" 4.37 2224.7 - 1.04E+06 - - - -4.2192 - 1.688 0.264 - 214.9 1 2 0 -0.0054 11 0 0 0 5.18E+07 3.17E+07 - - - 2.4055 0.9997 221125_WJC_METTL3_EV_vs_WT_F04.10601.10601.2 9.07E-08 22-Dec K.SVTC[160.03]TYSPALNK[136.11].M "sp|P04637|P53_HUMAN,tr|J3KP33|J3KP33_HUMAN,tr|A0A0U1RQC9|A0A0U1RQC9_HUMAN,tr|E7EQX7|E7EQX7_HUMAN,tr|E7EMR6|E7EMR6_HUMAN" 5 1347.6584 0.64 45132 10601 2 1347.661951 674.8365 Cellular tumor antigen p53 OS=Homo sapiens OX=9606 GN=TP53 PE=1 SV=4 7.92 2224.8 - 946543 - - - 2.6335 - 2.382 0.556 - 426.4 1 2 0 0.0035 12 0 0 0 2.05E+07 3.22E+07 - - - 5.4302 0.9997 221125_WJC_METTL3_EV_vs_WT_F04.10602.10602.3 0.0127 15/40 K.QLGVVALNSHK.S "sp|Q6ZU65|UBN2_HUMAN,tr|H7C4P8|H7C4P8_HUMAN,tr|C9J6Y5|C9J6Y5_HUMAN" 3 1164.6615 1.63 45133 10602 3 1164.662168 389.2278 Ubinuclein-2 OS=Homo sapiens OX=9606 GN=UBN2 PE=1 SV=2 8.76 2224.9 - 1.31E+06 - - - 0.5675 - 2.198 0.304 - 235.9 1 2 0 0.0007 11 0 0 0 3.26E+07 2.00E+07 - - - 4.1664 0.977 221125_WJC_METTL3_EV_vs_WT_F04.10604.10604.2 4.17E-05 24-Aug K.IIDSDEGPEC[160.03]HPP.V sp|Q08554|DSC1_HUMAN 1 1464.6191 - 45135 10604 2 1464.618578 733.3168 Desmocollin-1 OS=Homo sapiens OX=9606 GN=DSC1 PE=1 SV=2 3.91 2225.1 - 339740 - - - -0.3626 - 1.618 0.407 - 119.9 1 1 0 -0.0005 13 0 0 0 - - - - - 3.2819 0.9998 221125_WJC_METTL3_EV_vs_WT_F04.10606.10606.2 0.000164 18-Sep K.DYTVTQVPPK.H "sp|Q8N5Z5|KCD17_HUMAN,tr|A0A087WX35|A0A087WX35_HUMAN,tr|H0Y731|H0Y731_HUMAN" 3 1146.5921 2.4 45136 10606 2 1146.592915 574.3033 BTB\POZ domain-containing protein KCTD17 OS=Homo sapiens OX=9606 GN=KCTD17 PE=1 SV=3 5.83 2225.4 - 1.91E+06 - - - 0.7195 - 1.675 0.483 - 222.7 1 2 0 0.0008 10 0 0 0 9.16E+07 3.82E+07 - - - 4.048 0.9996 221125_WJC_METTL3_EV_vs_WT_F04.10608.10608.3 0.000306 16/40 K.QLGVVALNSHK[136.11].S "sp|Q6ZU65|UBN2_HUMAN,tr|H7C4P8|H7C4P8_HUMAN,tr|C9J6Y5|C9J6Y5_HUMAN" 3 1172.6757 1.59 45137 10608 3 1172.678325 391.8992 Ubinuclein-2 OS=Homo sapiens OX=9606 GN=UBN2 PE=1 SV=2 8.76 2225.6 - 997827 - - - 2.2325 - 2.344 0.339 - 226.4 1 2 0 0.0026 11 0 0 0 3.17E+07 2.00E+07 - - - 4.7388 0.9999 221125_WJC_METTL3_EV_vs_WT_F04.10609.10609.2 2.92E-06 24-Dec K.TVNQQTMAAPVVK.E "sp|Q9Y520|PRC2C_HUMAN,tr|E7EPN9|E7EPN9_HUMAN" 2 1385.7337 1.1 45138 10609 2 1385.734351 693.8741 Protein PRRC2C OS=Homo sapiens OX=9606 GN=PRRC2C PE=1 SV=4 8.41 2225.8 - 550143 - - - 0.4806 - 2.193 0.547 - 420.5 1 2 0 0.0007 13 0 0 0 3.57E+07 3.26E+07 - - - 5.0964 0.9999 221125_WJC_METTL3_EV_vs_WT_F04.10615.10615.2 7.06E-06 20-Dec R.LNQDQLDAVSK.Y "sp|Q14444|CAPR1_HUMAN,tr|G3V153|G3V153_HUMAN,tr|E9PLA9|E9PLA9_HUMAN" 3 1229.6252 0.97 45142 10615 2 1229.624869 615.8199 Caprin-1 OS=Homo sapiens OX=9606 GN=CAPRIN1 PE=1 SV=2 4.21 2226.5 - 3.40E+06 - - - -0.2537 - 2.526 0.464 - 552.7 1 2 0 -0.0003 11 0 0 0 5.06E+08 5.23E+08 - - - 4.9748 0.9997 221125_WJC_METTL3_EV_vs_WT_F04.10616.10616.2 0.000226 14-Dec K.KGFPVLSK.M "sp|O14744|ANM5_HUMAN,tr|H0YJX6|H0YJX6_HUMAN" 2 874.5276 2.75 45143 10616 2 874.527888 438.2711 Protein arginine N-methyltransferase 5 OS=Homo sapiens OX=9606 GN=PRMT5 PE=1 SV=4 10 2226.6 - 2.84E+06 - - - 0.2847 - 2.335 0.282 - 560.4 1 2 0 0.0002 8 0 0 0 7.54E+07 2.74E+07 - - - 3.6813 0.9996 221125_WJC_METTL3_EV_vs_WT_F04.10618.10618.2 0.0363 16-Oct R.QGVTQVLSR[166.11].L sp|Q9NW08|RPC2_HUMAN 1 996.5592 0.62 45145 10618 2 996.559469 499.2869 DNA-directed RNA polymerase III subunit RPC2 OS=Homo sapiens OX=9606 GN=POLR3B PE=1 SV=2 9.75 2226.8 - 648047 - - - 0.3071 - 2.022 0.311 - 400.2 1 2 0 0.0003 9 0 0 0 5.73E+06 9.20E+06 - - - 3.3749 0.9997 221125_WJC_METTL3_EV_vs_WT_F04.10619.10619.2 0.000546 14-Aug K.FC[160.03]SGSWDK[136.11].M sp|Q9GZL7|WDR12_HUMAN 1 993.4106 0.89 45146 10619 2 993.41134 497.7126 Ribosome biogenesis protein WDR12 OS=Homo sapiens OX=9606 GN=WDR12 PE=1 SV=2 5.83 2226.9 - 436305 - - - 0.7781 - 1.564 0.485 - 182.9 1 2 0 0.0008 8 0 0 0 9.22E+06 1.03E+07 - - - 3.9718 0.9999 221125_WJC_METTL3_EV_vs_WT_F04.10620.10620.2 2.53E-05 22-Oct R.AAEC[160.03]NIVVTQPR[166.11].R sp|Q08211|DHX9_HUMAN 1 1366.6903 1.01 45147 10620 2 1366.689167 684.3524 ATP-dependent RNA helicase A OS=Homo sapiens OX=9606 GN=DHX9 PE=1 SV=4 6.04 2227.1 - 294082 - - - -0.7954 - 2.318 0.593 - 381.5 1 2 0 -0.0011 12 0 0 0 1.55E+07 1.53E+07 - - - 5.6326 1 221125_WJC_METTL3_EV_vs_WT_F04.10625.10625.3 0.0301 14/44 R.LRPVNPNPLATK.G "sp|P51116|FXR2_HUMAN,tr|I3L1Z2|I3L1Z2_HUMAN" 2 1318.7721 1.51 45150 10625 3 1318.771609 440.598 Fragile X mental retardation syndrome-related protein 2 OS=Homo sapiens OX=9606 GN=FXR2 PE=1 SV=2 11 2227.6 - 2.25E+06 - - - -0.3875 - 2.716 0.483 - 262.7 1 2 0 -0.0005 12 0 0 0 7.87E+07 5.21E+07 - - - 6.6944 0.9996 221125_WJC_METTL3_EV_vs_WT_F04.10626.10626.3 0.000291 Oct-44 R.YMPQNPHIIATK.T "sp|Q16576|RBBP7_HUMAN,tr|Q5JP01|Q5JP01_HUMAN,tr|E9PC52|E9PC52_HUMAN" 3 1411.7282 0.96 45151 10626 3 1411.727613 471.5833 Histone-binding protein RBBP7 OS=Homo sapiens OX=9606 GN=RBBP7 PE=1 SV=1 8.6 2227.7 - 2.83E+06 - - - -0.4201 - 1.788 0.352 - 91.1 1 2 0 -0.0006 12 0 0 0 5.76E+07 6.02E+07 - - - 4.075 0.9996 221125_WJC_METTL3_EV_vs_WT_F04.10628.10628.2 0.0157 14-Jul R.DEIFAQSK.E sp|P35580|MYH10_HUMAN 1 936.4553 1 45153 10628 2 936.455594 469.2349 Myosin-10 OS=Homo sapiens OX=9606 GN=MYH10 PE=1 SV=3 4.37 2227.8 - 2.21E+06 - - - 0.3545 - 1.452 0.427 - 262.7 1 2 0 0.0003 8 0 0 0 4.15E+07 4.14E+07 - - - 3.3195 1 221125_WJC_METTL3_EV_vs_WT_F04.10629.10629.3 5.89E-05 14/44 R.LR[166.11]PVNPNPLATK[136.11].G "sp|P51116|FXR2_HUMAN,tr|I3L1Z2|I3L1Z2_HUMAN" 2 1336.7946 1.51 45154 10629 3 1336.79404 446.6055 Fragile X mental retardation syndrome-related protein 2 OS=Homo sapiens OX=9606 GN=FXR2 PE=1 SV=2 11 2227.9 - 1.91E+06 - - - -0.4114 - 2.458 0.462 - 314.1 1 2 0 -0.0005 12 0 0 0 7.87E+07 5.21E+07 - - - 6.1835 0.9989 221125_WJC_METTL3_EV_vs_WT_F04.10631.10631.2 0.116 14-Jul R.MQSLSLNK[136.11].- sp|Q13442|HAP28_HUMAN 1 927.4939 0.5 45156 10631 2 927.493439 464.7542 28 kDa heat- and acid-stable phosphoprotein OS=Homo sapiens OX=9606 GN=PDAP1 PE=1 SV=1 8.5 2228.1 - 1.29E+06 - - - -0.4992 - 1.588 0.258 - 140.4 1 2 0 -0.0005 8 0 0 0 9.25E+06 1.85E+07 - - - 2.3412 0.9998 221125_WJC_METTL3_EV_vs_WT_F04.10633.10633.2 0.0173 14-Aug K.FC[160.03]SGSWDK.M sp|Q9GZL7|WDR12_HUMAN 1 985.3964 0.86 45158 10633 2 985.396654 493.7055 Ribosome biogenesis protein WDR12 OS=Homo sapiens OX=9606 GN=WDR12 PE=1 SV=2 5.83 2228.3 - 632297 - - - 0.2913 - 1.487 0.518 - 166.6 1 2 0 0.0003 8 0 0 0 9.22E+06 1.07E+07 - - - 4.0635 0.9961 221125_WJC_METTL3_EV_vs_WT_F04.10635.10635.2 0.00126 18-Aug K.DVEEGDEKFE.- "sp|Q9Y3A5|SBDS_HUMAN,tr|A0A087X020|A0A087X020_HUMAN" 2 1195.4881 2.94 45160 10635 2 1195.488073 598.7513 Ribosome maturation protein SBDS OS=Homo sapiens OX=9606 GN=SBDS PE=1 SV=4 3.96 2228.5 - 540278 - - - -0.0042 - 1.458 0.449 - 121.7 1 2 1 0 10 0 0 0 6.72E+06 2.28E+06 - - - 3.4098 0.9832 221125_WJC_METTL3_EV_vs_WT_F04.10636.10636.2 0.000162 13/26 A.AAAVTAASTSYYGR.D "sp|Q9BWF3|RBM4_HUMAN,tr|E9PB51|E9PB51_HUMAN" 2 1387.6732 1.31 45161 10636 2 1387.67667 694.8439 RNA-binding protein 4 OS=Homo sapiens OX=9606 GN=RBM4 PE=1 SV=1 8.63 2228.7 - 414311 - - - 2.5056 - 2.834 0.526 - 481.4 1 1 0 0.0035 14 0 0 0 6.36E+06 4.86E+06 - - - 5.539 1 221125_WJC_METTL3_EV_vs_WT_F04.10637.10637.2 9.34E-09 14/26 A.AAAVTAASTSYYGR[166.11].D "sp|Q9BWF3|RBM4_HUMAN,tr|E9PB51|E9PB51_HUMAN" 2 1397.6815 1.31 45162 10637 2 1397.680571 699.848 RNA-binding protein 4 OS=Homo sapiens OX=9606 GN=RBM4 PE=1 SV=1 8.63 2228.8 - 320681 - - - -0.6382 - 3.008 0.588 - 695.7 1 1 0 -0.0009 14 0 0 0 6.36E+06 4.86E+06 - - - 6.1473 0.999 221125_WJC_METTL3_EV_vs_WT_F04.10640.10640.3 0.000159 Dec-44 R.YMPQNPHIIATK[136.11].T "sp|Q16576|RBBP7_HUMAN,tr|Q5JP01|Q5JP01_HUMAN,tr|E9PC52|E9PC52_HUMAN" 3 1419.7424 1.17 45163 10640 3 1419.743493 474.2547 Histone-binding protein RBBP7 OS=Homo sapiens OX=9606 GN=RBBP7 PE=1 SV=1 8.6 2229.2 - 2.92E+06 - - - 0.7656 - 1.98 0.26 - 130.7 1 2 0 0.0011 12 0 0 0 5.72E+07 4.88E+07 - - - 3.3319 0.9991 221125_WJC_METTL3_EV_vs_WT_F04.10642.10642.2 0.0115 16-Jul R.DSFIGENSR[166.11].T "sp|O00139|KIF2A_HUMAN,sp|Q99661|KIF2C_HUMAN,tr|A0A6Q8PFA6|A0A6Q8PFA6_HUMAN,tr|A0A6Q8PGG1|A0A6Q8PGG1_HUMAN,tr|A0A6Q8PGH7|A0A6Q8PGH7_HUMAN,tr|A0A6Q8PG37|A0A6Q8PG37_HUMAN,tr|A0A6Q8PH57|A0A6Q8PH57_HUMAN,tr|H0Y5Z9|H0Y5Z9_HUMAN" 8 1033.4704 1.12 45165 10642 2 1033.469217 517.7425 Kinesin-like protein KIF2A OS=Homo sapiens OX=9606 GN=KIF2A PE=1 SV=3 4.37 2229.4 - 1.68E+06 - - - -1.1524 - 1.284 0.402 - 130.7 1 2 0 -0.0012 9 0 0 0 2.51E+07 2.24E+07 - - - 2.733 0.9973 221125_WJC_METTL3_EV_vs_WT_F04.10643.10643.2 0.0851 14-Jul R.MQSLSLNK.- sp|Q13442|HAP28_HUMAN 1 919.4797 0.49 45166 10643 2 919.479355 460.7471 28 kDa heat- and acid-stable phosphoprotein OS=Homo sapiens OX=9606 GN=PDAP1 PE=1 SV=1 8.5 2229.5 - 894314 - - - -0.3774 - 1.415 0.199 - 168.5 1 2 0 -0.0003 8 0 0 0 9.15E+06 1.85E+07 - - - 1.5576 0.9986 221125_WJC_METTL3_EV_vs_WT_F04.10644.10644.2 0.00182 18-Oct K.SAPSILSNGR.L "sp|Q8NDD1|CA131_HUMAN,tr|Q5TBI2|Q5TBI2_HUMAN" 2 1000.5302 0.82 45167 10644 2 1000.527415 501.2724 Uncharacterized protein C1orf131 OS=Homo sapiens OX=9606 GN=C1orf131 PE=1 SV=4 9.47 2229.6 - 675694 - - - -2.7415 - 1.671 0.386 - 217.9 1 2 0 -0.0027 10 0 0 0 9.71E+06 1.19E+07 - - - 3.3243 0.9997 221125_WJC_METTL3_EV_vs_WT_F04.10645.10645.3 0.000919 Nov-52 K.IAVAAASKPAVEIK.Q "sp|P29373|RABP2_HUMAN,tr|Q5SYZ4|Q5SYZ4_HUMAN" 2 1366.8184 999 45168 10645 3 1366.819023 456.6134 Cellular retinoic acid-binding protein 2 OS=Homo sapiens OX=9606 GN=CRABP2 PE=1 SV=2 8.59 2229.7 - 551107 - - - 0.4551 - 2.222 0.32 - 130.6 1 2 0 0.0006 14 0 0 0 6.70E+06 0.00E+00 - - - 4.2293 1 221125_WJC_METTL3_EV_vs_WT_F04.10646.10646.3 2.21E-05 15/44 R.C[160.03]GAALAGHQLIR[166.11].G sp|P78527|PRKDC_HUMAN 1 1275.6745 0.93 45169 10646 3 1275.675259 426.2321 DNA-dependent protein kinase catalytic subunit OS=Homo sapiens OX=9606 GN=PRKDC PE=1 SV=3 8.26 2229.8 - 483319 - - - 0.5597 - 2.858 0.46 - 429 1 2 0 0.0007 12 0 0 0 1.05E+07 1.14E+07 - - - 6.5791 0.9826 221125_WJC_METTL3_EV_vs_WT_F04.10648.10648.2 0.000322 26-Dec R.LGEASDSELADADK[136.11].A "sp|Q5SW79|CE170_HUMAN,tr|H0Y2V6|H0Y2V6_HUMAN" 2 1427.6507 1.36 45171 10648 2 1428.650086 714.8326 Centrosomal protein of 170 kDa OS=Homo sapiens OX=9606 GN=CEP170 PE=1 SV=1 3.77 2230.1 - 312913 - - - 699.9982 - 2.716 0.511 - 525.9 1 2 0 0.9994 14 0 0 0 8.16E+06 5.99E+06 - - - 5.0088 0.9388 221125_WJC_METTL3_EV_vs_WT_F04.10650.10650.2 0.363 18-Jul K.TFC[160.03]WSTNLIR[166.11].H sp|Q5CZA5|ZN805_HUMAN 1 1306.6368 0 45172 10650 2 1306.643213 654.3257 Zinc finger protein 805 OS=Homo sapiens OX=9606 GN=ZNF805 PE=2 SV=3 7.91 2230.4 - 1.10E+06 - - - 4.9371 - 1.309 0.215 - 104.2 1 2 0 0.0065 10 0 0 0 3.75E+05 3.01E+08 - - - 1.3786 0.9997 221125_WJC_METTL3_EV_vs_WT_F04.10652.10652.2 0.00479 20-Oct R.AYTPPEDLQSR[166.11].L sp|Q8N5N7|RM50_HUMAN 1 1285.6178 1.69 45173 10652 2 1285.616616 643.8162 "39S ribosomal protein L50, mitochondrial OS=Homo sapiens OX=9606 GN=MRPL50 PE=1 SV=2" 4.37 2230.6 - 1.12E+06 - - - -0.9217 - 1.891 0.423 - 315.6 1 2 0 -0.0012 11 0 0 0 6.29E+07 3.71E+07 - - - 3.8884 0.9956 221125_WJC_METTL3_EV_vs_WT_F04.10653.10653.3 0.00453 Nov-32 K.SVNELIYK[136.11]R[166.11].G "sp|P18124|RL7_HUMAN,tr|A8MUD9|A8MUD9_HUMAN" 2 1138.6465 0.001 45174 10653 3 1138.640727 380.5561 60S ribosomal protein L7 OS=Homo sapiens OX=9606 GN=RPL7 PE=1 SV=1 8.31 2230.7 - 1.81E+06 - - - -5.0946 - 2.209 0.308 - 169.1 1 2 0 -0.0058 9 0 0 0 0.00E+00 5.21E+07 - - - 4.3608 0.9999 221125_WJC_METTL3_EV_vs_WT_F04.10654.10654.2 1.14E-06 20-Aug R.SMMSSYSAADR.S "sp|P18583|SON_HUMAN,tr|H7C1M2|H7C1M2_HUMAN" 2 1204.4853 1.11 45175 10654 2 1204.484185 603.2499 Protein SON OS=Homo sapiens OX=9606 GN=SON PE=1 SV=4 5.55 2230.7 - 3.20E+06 - - - -0.8908 - 1.812 0.594 - 231.7 1 2 0 -0.0011 11 0 0 0 2.21E+07 1.99E+07 - - - 5.036 0.9999 221125_WJC_METTL3_EV_vs_WT_F04.10656.10656.2 1.98E-05 13/20 R.QLAEEDLAQQR.A sp|Q15149|PLEC_HUMAN 1 1299.6419 0.82 45177 10656 2 1299.643244 650.8282 Plectin OS=Homo sapiens OX=9606 GN=PLEC PE=1 SV=3 4.14 2231 - 604267 - - - 1.0395 - 2.088 0.542 - 520.2 1 2 0 0.0014 11 0 0 0 1.33E+07 1.61E+07 - - - 5.0354 0.8955 221125_WJC_METTL3_EV_vs_WT_F04.10657.10657.3 0.249 Aug-36 R.LKETLAQLSR.E "sp|Q9H8V3|ECT2_HUMAN,tr|H7C3G1|H7C3G1_HUMAN" 2 1157.6768 0.79 45178 10657 3 1157.674963 386.8996 Protein ECT2 OS=Homo sapiens OX=9606 GN=ECT2 PE=1 SV=4 8.75 2231.1 - 423773 - - - -1.6058 - 1.609 0.137 - 77.1 1 2 1 -0.0019 10 0 0 0 4.28E+06 5.45E+06 - - - 1.4559 0.9997 221125_WJC_METTL3_EV_vs_WT_F04.10658.10658.3 0.0263 Dec-40 K.VLIVYAHQEPK[136.11].S "sp|P16083|NQO2_HUMAN,tr|Q5TD07|Q5TD07_HUMAN,tr|Q5TD05|Q5TD05_HUMAN,tr|A2A2U4|A2A2U4_HUMAN" 4 1303.738 1.1 45179 10658 3 1303.738035 435.5866 Ribosyldihydronicotinamide dehydrogenase [quinone] OS=Homo sapiens OX=9606 GN=NQO2 PE=1 SV=5 6.72 2231.3 - 273918 - - - 0.0483 - 2.243 0.298 - 219.8 1 2 0 0.0001 11 0 0 0 8.09E+06 7.38E+06 - - - 4.1573 0.9995 221125_WJC_METTL3_EV_vs_WT_F04.10662.10662.2 0.0239 18-Dec K.SAPSILSNGR[166.11].L "sp|Q8NDD1|CA131_HUMAN,tr|Q5TBI2|Q5TBI2_HUMAN" 2 1010.5384 0.82 45181 10662 2 1010.53937 506.2765 Uncharacterized protein C1orf131 OS=Homo sapiens OX=9606 GN=C1orf131 PE=1 SV=4 9.47 2231.8 - 831023 - - - 0.9322 - 2.002 0.326 - 523 1 2 0 0.0009 10 0 0 0 9.71E+06 1.19E+07 - - - 3.3861 0.9994 221125_WJC_METTL3_EV_vs_WT_F04.10665.10665.2 0.0103 14-Sep K.VPSLQHFR.K "sp|Q01664|TFAP4_HUMAN,tr|I3L301|I3L301_HUMAN,tr|I3L4L6|I3L4L6_HUMAN" 3 982.5348 0.85 45184 10665 2 982.535858 492.2747 Transcription factor AP-4 OS=Homo sapiens OX=9606 GN=TFAP4 PE=1 SV=2 9.73 2232.1 - 541584 - - - 1.0269 - 1.829 0.314 - 337.4 1 2 0 0.001 8 0 0 0 1.09E+07 1.28E+07 - - - 3.1808 0.9992 221125_WJC_METTL3_EV_vs_WT_F04.10666.10666.2 0.00259 22-Sep R.LRPVNPNPLATK.G "sp|P51116|FXR2_HUMAN,tr|I3L1Z2|I3L1Z2_HUMAN" 2 1318.7721 1.93 45185 10666 2 1318.769708 660.3933 Fragile X mental retardation syndrome-related protein 2 OS=Homo sapiens OX=9606 GN=FXR2 PE=1 SV=2 11 2232.3 - 415191 - - - -1.829 - 1.918 0.33 - 165.6 1 2 0 -0.0024 12 0 0 0 7.40E+06 3.83E+06 - - - 3.1913 0.9996 221125_WJC_METTL3_EV_vs_WT_F04.10667.10667.2 0.00625 22-Sep R.LR[166.11]PVNPNPLATK[136.11].G "sp|P51116|FXR2_HUMAN,tr|I3L1Z2|I3L1Z2_HUMAN" 2 1336.7946 1.93 45186 10667 2 1336.794415 669.4046 Fragile X mental retardation syndrome-related protein 2 OS=Homo sapiens OX=9606 GN=FXR2 PE=1 SV=2 11 2232.4 - 261536 - - - -0.1309 - 1.883 0.328 - 157.3 1 2 0 -0.0002 12 0 0 0 7.40E+06 3.83E+06 - - - 3.1287 1 221125_WJC_METTL3_EV_vs_WT_F04.10668.10668.2 1.00E-06 22-Sep R.LEC[160.03]DEEC[160.03]SALER.K sp|Q12986|NFX1_HUMAN 1 1509.6076 3.43 45187 10668 2 1509.604798 755.8111 Transcriptional repressor NF-X1 OS=Homo sapiens OX=9606 GN=NFX1 PE=1 SV=2 3.91 2232.5 - 195501 - - - -1.829 - 1.926 0.714 - 244.1 1 2 0 -0.0028 12 0 0 0 2.62E+06 7.63E+05 - - - 6.0383 0.9997 221125_WJC_METTL3_EV_vs_WT_F04.10671.10671.3 0.00346 Nov-36 R.VAEFHTELER[166.11].L "sp|P48556|PSMD8_HUMAN,tr|K7EJR3|K7EJR3_HUMAN,tr|R4GMR5|R4GMR5_HUMAN,tr|K7EJC1|K7EJC1_HUMAN,tr|K7ERW6|K7ERW6_HUMAN" 5 1239.6123 0.69 45188 10671 3 1239.611333 414.2114 26S proteasome non-ATPase regulatory subunit 8 OS=Homo sapiens OX=9606 GN=PSMD8 PE=1 SV=2 4.75 2232.9 - 1.78E+06 - - - -0.797 - 2.178 0.314 - 249.8 1 2 0 -0.001 10 0 0 0 1.50E+07 2.19E+07 - - - 4.3138 0.9967 221125_WJC_METTL3_EV_vs_WT_F04.10672.10672.2 0.0692 18-Jul R.AVDDGVNTFK[136.11].V sp|P50990|TCPQ_HUMAN 1 1072.528 0.42 45189 10672 2 1072.528728 537.2713 T-complex protein 1 subunit theta OS=Homo sapiens OX=9606 GN=CCT8 PE=1 SV=4 4.21 2233 - 1.36E+06 - - - 0.6424 - 1.421 0.202 - 111.6 1 2 0 0.0007 10 0 0 0 3.35E+07 8.07E+07 - - - 1.5135 0.9999 221125_WJC_METTL3_EV_vs_WT_F04.10673.10673.3 0.000258 Nov-36 R.VAEFHTELER.L "sp|P48556|PSMD8_HUMAN,tr|K7EJR3|K7EJR3_HUMAN,tr|R4GMR5|R4GMR5_HUMAN,tr|K7EJC1|K7EJC1_HUMAN,tr|K7ERW6|K7ERW6_HUMAN" 5 1229.6041 0.68 45190 10673 3 1229.602956 410.8753 26S proteasome non-ATPase regulatory subunit 8 OS=Homo sapiens OX=9606 GN=PSMD8 PE=1 SV=2 4.75 2233.1 - 962346 - - - -0.8905 - 2.132 0.371 - 213.3 1 2 0 -0.0011 10 0 0 0 1.52E+07 2.22E+07 - - - 4.8869 0.9964 221125_WJC_METTL3_EV_vs_WT_F04.10675.10675.2 0.348 14-Jul K.VPSLQHFR[166.11].K "sp|Q01664|TFAP4_HUMAN,tr|I3L301|I3L301_HUMAN,tr|I3L4L6|I3L4L6_HUMAN" 3 992.5431 1.19 45192 10675 2 992.542639 497.2788 Transcription factor AP-4 OS=Homo sapiens OX=9606 GN=TFAP4 PE=1 SV=2 9.73 2233.4 - 633799 - - - -0.4836 - 1.632 0.115 - 168.2 1 2 0 -0.0005 8 0 0 0 1.60E+07 1.34E+07 - - - 1.3675 0.9198 221125_WJC_METTL3_EV_vs_WT_F04.10676.10676.2 0.025 22-Sep G.GLGQGGLAATLR.D "sp|Q9HCQ5|GALT9_HUMAN,tr|J3KNN1|J3KNN1_HUMAN" 2 1112.6302 58.36 45193 10676 2 1112.628707 557.3224 Polypeptide N-acetylgalactosaminyltransferase 9 OS=Homo sapiens OX=9606 GN=GALNT9 PE=1 SV=3 9.75 2233.5 - 613799 - - - -1.3473 - 1.872 0.225 - 166.2 1 1 0 -0.0015 12 0 0 0 6.59E+07 1.13E+06 - - - 2.3521 0.9954 221125_WJC_METTL3_EV_vs_WT_F04.10678.10678.3 0.0525 Sep-40 R.NPEAALSPTFR[166.11].S "sp|Q86U44|MTA70_HUMAN,tr|B4E349|B4E349_HUMAN,tr|F5H6D8|F5H6D8_HUMAN,tr|B4DTN4|B4DTN4_HUMAN" 4 1211.6174 0.02 45195 10678 3 1211.616991 404.8797 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 6 2233.8 - 525924 - - - -0.3433 - 1.528 0.228 - 111.7 1 2 0 -0.0004 11 0 0 0 4.66E+05 2.39E+07 - - - 2.2863 0.9818 221125_WJC_METTL3_EV_vs_WT_F04.10679.10679.2 5.90E-05 20-Aug L.EGNEQFINAAK.L "sp|P07478|TRY2_HUMAN,sp|P35030|TRY3_HUMAN,sp|Q8NHM4|TRY6_HUMAN,sp|P07477|TRY1_HUMAN,tr|E7EQ64|E7EQ64_HUMAN,tr|A0A7P0MNE9|A0A7P0MNE9_HUMAN,tr|A6XMV9|A6XMV9_HUMAN,tr|A0A0J9YYC8|A0A0J9YYC8_HUMAN,tr|A6XMV8|A6XMV8_HUMAN,tr|H0Y8D1|H0Y8D1_HUMAN" 10 1219.5833 999 45196 10679 2 1219.582205 610.7989 Trypsin-2 OS=Homo sapiens OX=9606 GN=PRSS2 PE=1 SV=1 4.53 2233.9 - 432290 - - - -0.911 - 1.596 0.461 - 195 1 1 0 -0.0011 11 0 0 0 2.79E+07 0.00E+00 - - - 3.7103 0.9983 221125_WJC_METTL3_EV_vs_WT_F04.10680.10680.2 0.000121 22-Jul K.VVGQTTPESFEK[136.11].A sp|Q02952|AKA12_HUMAN 1 1328.6703 0.93 45197 10680 2 1328.665809 665.3424 A-kinase anchor protein 12 OS=Homo sapiens OX=9606 GN=AKAP12 PE=1 SV=4 4.53 2234 - 320043 - - - -3.4147 - 1.519 0.474 - 106.2 1 2 0 -0.0045 12 0 0 0 3.48E+06 3.76E+06 - - - 3.6405 0.9997 221125_WJC_METTL3_EV_vs_WT_F04.10684.10684.2 0.000775 18-Aug K.LC[160.03]FSTAQHAS.- "sp|P14866|HNRPL_HUMAN,tr|A0A3B3ITJ4|A0A3B3ITJ4_HUMAN,tr|M0QXS5|M0QXS5_HUMAN" 3 1120.4971 - 45200 10684 2 1120.497676 561.2558 Heterogeneous nuclear ribonucleoprotein L OS=Homo sapiens OX=9606 GN=HNRNPL PE=1 SV=2 6.73 2234.5 - 7.55E+06 - - - 0.4748 - 1.733 0.431 - 179.4 1 2 0 0.0005 10 0 0 0 - - - - - 3.759 0.9997 221125_WJC_METTL3_EV_vs_WT_F04.10687.10687.2 0.000121 16-Aug K.EFTAQNLGK.L "sp|O15372|EIF3H_HUMAN,tr|B3KS98|B3KS98_HUMAN,tr|A0A087WZK9|A0A087WZK9_HUMAN" 3 1006.5084 1.74 45203 10687 2 1006.508692 504.2615 Eukaryotic translation initiation factor 3 subunit H OS=Homo sapiens OX=9606 GN=EIF3H PE=1 SV=1 6.1 2234.7 - 2.08E+06 - - - 0.3299 - 1.545 0.467 - 306.4 1 2 0 0.0003 9 0 0 0 2.64E+08 1.51E+08 - - - 3.7487 0.9904 221125_WJC_METTL3_EV_vs_WT_F04.10688.10688.2 0.0243 16-Sep R.GSITQGIPR.S "sp|Q9Y618|NCOR2_HUMAN,tr|C9JQE8|C9JQE8_HUMAN,tr|C9J7T7|C9J7T7_HUMAN,tr|C9JE98|C9JE98_HUMAN,tr|C9J0Q5|C9J0Q5_HUMAN,tr|A0A384DVL6|A0A384DVL6_HUMAN" 6 927.5138 1.17 45204 10688 2 927.51662 464.7642 Nuclear receptor corepressor 2 OS=Homo sapiens OX=9606 GN=NCOR2 PE=1 SV=3 9.75 2234.9 - 901776 - - - 3.0619 - 1.916 0.117 - 258 1 2 0 0.0028 9 0 0 0 1.36E+07 1.16E+07 - - - 1.7854 0.9993 221125_WJC_METTL3_EV_vs_WT_F04.10690.10690.2 1.58E-06 24-Oct K.LNQPPEDGISSVK[136.11].F "sp|O43684|BUB3_HUMAN,tr|J3QT28|J3QT28_HUMAN,tr|J3QSX4|J3QSX4_HUMAN" 3 1390.7184 0.66 45206 10690 2 1390.722964 696.3665 Mitotic checkpoint protein BUB3 OS=Homo sapiens OX=9606 GN=BUB3 PE=1 SV=1 4.37 2235.1 - 539684 - - - 3.3112 - 2.064 0.543 - 280.9 1 2 0 0.0046 13 0 0 0 1.00E+07 1.52E+07 - - - 4.91 0.9995 221125_WJC_METTL3_EV_vs_WT_F04.10694.10694.2 0.000501 20-Sep K.ATEISTAVVQR.S sp|Q8N3X1|FNBP4_HUMAN 1 1173.6354 1.18 45210 10694 2 1173.638346 587.825 Formin-binding protein 4 OS=Homo sapiens OX=9606 GN=FNBP4 PE=1 SV=3 6.05 2235.6 - 364174 - - - 2.5519 - 2.041 0.461 - 298.9 1 2 0 0.003 11 0 0 0 2.25E+06 1.91E+06 - - - 4.375 0.9996 221125_WJC_METTL3_EV_vs_WT_F04.10700.10700.2 0.00286 20-Jul R.SMMSSYSAADR[166.11].S "sp|P18583|SON_HUMAN,tr|H7C1M2|H7C1M2_HUMAN" 2 1214.4935 1.11 45215 10700 2 1214.495455 608.254 Protein SON OS=Homo sapiens OX=9606 GN=SON PE=1 SV=4 5.55 2236.4 - 1.00E+06 - - - 1.5867 - 1.419 0.517 - 102.1 1 2 0 0.0019 11 0 0 0 2.21E+07 1.99E+07 - - - 3.8057 0.9997 221125_WJC_METTL3_EV_vs_WT_F04.10702.10702.2 8.28E-05 18-Sep R.AVDDGVNTFK.V sp|P50990|TCPQ_HUMAN 1 1064.5138 0.41 45217 10702 2 1064.515359 533.2642 T-complex protein 1 subunit theta OS=Homo sapiens OX=9606 GN=CCT8 PE=1 SV=4 4.21 2236.5 - 1.90E+06 - - - 1.4279 - 1.736 0.505 - 194.6 1 2 0 0.0015 10 0 0 0 3.32E+07 8.06E+07 - - - 4.3101 0.9934 221125_WJC_METTL3_EV_vs_WT_F04.10703.10703.2 0.0671 12-Jul K.KIDYFER.A sp|Q14152|EIF3A_HUMAN 1 969.492 0.91 45218 10703 2 969.49515 485.7533 Eukaryotic translation initiation factor 3 subunit A OS=Homo sapiens OX=9606 GN=EIF3A PE=1 SV=1 6.07 2236.6 - 1.02E+06 - - - 3.2677 - 1.458 0.269 - 193.5 1 2 0 0.0032 7 0 0 0 1.43E+07 1.57E+07 - - - 2.2216 0.9998 221125_WJC_METTL3_EV_vs_WT_F04.10704.10704.2 4.36E-05 20-Nov K.ELAAQLNEEAK.R sp|Q9Y5B9|SP16H_HUMAN 1 1214.6143 1.16 45219 10704 2 1214.615115 608.3144 FACT complex subunit SPT16 OS=Homo sapiens OX=9606 GN=SUPT16H PE=1 SV=1 4.25 2236.7 - 1.00E+06 - - - 0.6858 - 2.003 0.457 - 316.4 1 2 0 0.0008 11 0 0 0 3.14E+07 2.71E+07 - - - 4.2953 0.9999 221125_WJC_METTL3_EV_vs_WT_F04.10706.10706.2 2.84E-05 22-Dec R.GDVQAVAYEEPK.H sp|Q15797|SMAD1_HUMAN 1 1304.6248 0.73 45221 10706 2 1304.625306 653.3197 Mothers against decapentaplegic homolog 1 OS=Homo sapiens OX=9606 GN=SMAD1 PE=1 SV=1 4.14 2237 - 565128 - - - 0.3526 - 2.21 0.542 - 529.5 1 2 0 0.0005 12 0 0 0 6.06E+06 8.35E+06 - - - 5.1306 0.9999 221125_WJC_METTL3_EV_vs_WT_F04.10708.10708.2 0.000206 18-Oct K.NLDDTIDDEK.L "sp|Q13310|PABP4_HUMAN,sp|P0CB38|PAB4L_HUMAN,tr|A0A7I2V5W9|A0A7I2V5W9_HUMAN,tr|H0YEU6|H0YEU6_HUMAN,tr|B1ANR0|B1ANR0_HUMAN,tr|A0A7I2V4L7|A0A7I2V4L7_HUMAN,tr|A0A7I2V598|A0A7I2V598_HUMAN,tr|H0Y5F5|H0Y5F5_HUMAN" 8 1176.5146 1.59 45223 10708 2 1176.514956 589.2646 Polyadenylate-binding protein 4 OS=Homo sapiens OX=9606 GN=PABPC4 PE=1 SV=1 3.71 2237.3 - 312597 - - - 0.2796 - 2.026 0.554 - 319 1 2 0 0.0003 10 0 0 0 6.90E+07 4.33E+07 - - - 5.1036 0.9985 221125_WJC_METTL3_EV_vs_WT_F04.10710.10710.3 0.013 Sep-36 K.ALK[136.11]PANMLER[166.11].L "sp|Q9BXJ9|NAA15_HUMAN,tr|A0A0B4J1W3|A0A0B4J1W3_HUMAN" 2 1159.6502 0.27 45225 10710 3 1159.652917 387.5574 "N-alpha-acetyltransferase 15, NatA auxiliary subunit OS=Homo sapiens OX=9606 GN=NAA15 PE=1 SV=1" 8.79 2237.5 - 180234 - - - 2.3136 - 1.698 0.321 - 120.7 1 2 0 0.0027 10 0 0 0 3.39E+06 1.26E+07 - - - 3.6643 0.9999 221125_WJC_METTL3_EV_vs_WT_F04.10715.10715.3 0.00154 Nov-32 K.LR[166.11]PGFMEDR[166.11].G sp|Q5BKZ1|ZN326_HUMAN 1 1139.5661 0.001 45228 10715 3 1139.565198 380.8626 DBIRD complex subunit ZNF326 OS=Homo sapiens OX=9606 GN=ZNF326 PE=1 SV=2 6.07 2238.1 - 1.23E+06 - - - -0.7503 - 1.986 0.386 - 206.7 1 2 0 -0.0009 9 0 0 0 0.00E+00 1.25E+07 - - - 4.9111 0.9997 221125_WJC_METTL3_EV_vs_WT_F04.10716.10716.2 0.000389 18-Sep K.NLDDTIDDEK[136.11].L "sp|Q13310|PABP4_HUMAN,sp|P0CB38|PAB4L_HUMAN,tr|A0A7I2V5W9|A0A7I2V5W9_HUMAN,tr|H0YEU6|H0YEU6_HUMAN,tr|B1ANR0|B1ANR0_HUMAN,tr|A0A7I2V4L7|A0A7I2V4L7_HUMAN,tr|A0A7I2V598|A0A7I2V598_HUMAN,tr|H0Y5F5|H0Y5F5_HUMAN" 8 1184.5288 1.59 45229 10716 2 1184.529297 593.2717 Polyadenylate-binding protein 4 OS=Homo sapiens OX=9606 GN=PABPC4 PE=1 SV=1 3.71 2238.2 - 1.22E+06 - - - 0.3968 - 1.597 0.436 - 225.8 1 2 0 0.0005 10 0 0 0 6.90E+07 4.33E+07 - - - 3.5678 0.8627 221125_WJC_METTL3_EV_vs_WT_F04.10717.10717.2 0.125 14-Sep L.KEELAYLR.K "sp|P08779|K1C16_HUMAN,tr|K7ENW6|K7ENW6_HUMAN" 2 1020.5604 3.28 45230 10717 2 1020.562119 511.2875 "Keratin, type I cytoskeletal 16 OS=Homo sapiens OX=9606 GN=KRT16 PE=1 SV=4" 6.14 2238.3 - 1.05E+06 - - - 1.6893 - 1.536 0.238 - 294.5 1 1 0 0.0017 8 0 0 0 9.70E+06 2.96E+06 - - - 2.0927 0.9996 221125_WJC_METTL3_EV_vs_WT_F04.10718.10718.2 0.0539 20-Aug R.TTSAGTGGMWR[166.11].F sp|P60468|SC61B_HUMAN 1 1133.5163 1.57 45231 10718 2 1133.515356 567.7654 Protein transport protein Sec61 subunit beta OS=Homo sapiens OX=9606 GN=SEC61B PE=1 SV=2 9.41 2238.4 - 1.10E+06 - - - -0.8434 - 1.666 0.392 - 199.7 1 2 0 -0.001 11 0 0 0 3.04E+07 1.93E+07 - - - 3.3168 0.9997 221125_WJC_METTL3_EV_vs_WT_F04.10719.10719.2 0.00113 24-Oct K.LNQPPEDGISSVK.F "sp|O43684|BUB3_HUMAN,tr|J3QT28|J3QT28_HUMAN,tr|J3QSX4|J3QSX4_HUMAN" 3 1382.7042 0.65 45232 10719 2 1382.705244 692.3594 Mitotic checkpoint protein BUB3 OS=Homo sapiens OX=9606 GN=BUB3 PE=1 SV=1 4.37 2238.5 - 666329 - - - 0.7847 - 1.83 0.428 - 299.1 1 2 0 0.0011 13 0 0 0 9.92E+06 1.52E+07 - - - 3.7529 0.9999 221125_WJC_METTL3_EV_vs_WT_F04.10722.10722.3 0.000511 Dec-40 K.VLIVYAHQEPK.S "sp|P16083|NQO2_HUMAN,tr|Q5TD07|Q5TD07_HUMAN,tr|Q5TD05|Q5TD05_HUMAN,tr|A2A2U4|A2A2U4_HUMAN" 4 1295.7238 0.98 45235 10722 3 1295.723284 432.9152 Ribosyldihydronicotinamide dehydrogenase [quinone] OS=Homo sapiens OX=9606 GN=NQO2 PE=1 SV=5 6.72 2238.9 - 334420 - - - -0.3766 - 2.071 0.432 - 188.9 1 2 0 -0.0005 11 0 0 0 2.67E+06 2.72E+06 - - - 5.4244 0.9611 221125_WJC_METTL3_EV_vs_WT_F04.10723.10723.2 0.00515 20-Aug R.AESEEGPDVLR.W "sp|Q15437|SC23B_HUMAN,tr|Q5QPE1|Q5QPE1_HUMAN,tr|A0A2R8YFH5|A0A2R8YFH5_HUMAN" 3 1200.5622 1.99 45236 10723 2 1200.570088 601.2884 Protein transport protein Sec23B OS=Homo sapiens OX=9606 GN=SEC23B PE=1 SV=2 4 2239 - 308486 - - - 6.5319 - 1.534 0.33 - 176.8 1 2 0 0.0078 11 0 0 0 3.74E+06 1.88E+06 - - - 2.6334 0.9858 221125_WJC_METTL3_EV_vs_WT_F04.10726.10726.2 0.000378 12-Sep V.PNLHVMK[136.11].A "sp|Q9NQ39|RS10L_HUMAN,sp|P46783|RS10_HUMAN,tr|A0A2R8Y6L3|A0A2R8Y6L3_HUMAN,tr|F6U211|F6U211_HUMAN,tr|A0A1W2PQS6|A0A1W2PQS6_HUMAN,tr|A0A2R8YFH6|A0A2R8YFH6_HUMAN,tr|A0A2R8Y7H1|A0A2R8Y7H1_HUMAN,tr|S4R435|S4R435_HUMAN" 8 845.4673 1.18 45238 10726 2 845.467305 423.7409 Putative 40S ribosomal protein S10-like OS=Homo sapiens OX=9606 GN=RPS10P5 PE=5 SV=1 9.18 2239.4 - 2.00E+06 - - - 0.013 - 2.072 0.338 - 268.5 1 1 0 0 7 0 0 0 7.70E+08 6.54E+08 - - - 3.8458 0.9933 221125_WJC_METTL3_EV_vs_WT_F04.10728.10728.2 0.00281 12-Oct V.PNLHVMK.A "sp|Q9NQ39|RS10L_HUMAN,sp|P46783|RS10_HUMAN,tr|A0A2R8Y6L3|A0A2R8Y6L3_HUMAN,tr|F6U211|F6U211_HUMAN,tr|A0A1W2PQS6|A0A1W2PQS6_HUMAN,tr|A0A2R8YFH6|A0A2R8YFH6_HUMAN,tr|A0A2R8Y7H1|A0A2R8Y7H1_HUMAN,tr|S4R435|S4R435_HUMAN" 8 837.4531 1.18 45239 10728 2 837.4534 419.7338 Putative 40S ribosomal protein S10-like OS=Homo sapiens OX=9606 GN=RPS10P5 PE=5 SV=1 9.18 2239.6 - 2.27E+06 - - - 0.3654 - 2.152 0.489 - 355.1 1 1 0 0.0003 7 0 0 0 7.70E+08 6.54E+08 - - - 5.081 0.8649 221125_WJC_METTL3_EV_vs_WT_F04.10729.10729.2 0.589 16-Jun R.LK[136.11]MLYAATR[166.11].A "sp|Q6IBS0|TWF2_HUMAN,tr|A0A7I2V2U8|A0A7I2V2U8_HUMAN,tr|D6RG15|D6RG15_HUMAN,tr|A0A7I2V5D3|A0A7I2V5D3_HUMAN" 4 1083.623 1.26 45240 10729 2 1083.623019 542.8188 Twinfilin-2 OS=Homo sapiens OX=9606 GN=TWF2 PE=1 SV=2 9.99 2239.6 - 2.33E+06 - - - 0.0581 - 1.499 0.081 - 68.3 8 2 1 0.0001 9 0 0 0 3.84E+07 3.05E+07 - - - 0.4069 0.9994 221125_WJC_METTL3_EV_vs_WT_F04.10731.10731.2 0.000334 18-Nov R.VVTQNIC[160.03]QYR[166.11].S "sp|Q8N163|CCAR2_HUMAN,tr|A0A087X2B6|A0A087X2B6_HUMAN,tr|H0YB24|H0YB24_HUMAN,tr|G3V119|G3V119_HUMAN" 4 1289.6426 3.31 45242 10731 2 1289.64381 645.8286 Cell cycle and apoptosis regulator protein 2 OS=Homo sapiens OX=9606 GN=CCAR2 PE=1 SV=2 8.19 2239.8 - 968742 - - - 0.9569 - 2.162 0.269 - 414.2 1 2 0 0.0012 10 0 0 0 3.71E+07 1.12E+07 - - - 3.1796 0.9997 221125_WJC_METTL3_EV_vs_WT_F04.10733.10733.2 0.00238 22-Aug R.LSASTASELSPK.S "sp|Q3KQU3|MA7D1_HUMAN,tr|D3DPS3|D3DPS3_HUMAN,tr|H0YF21|H0YF21_HUMAN" 3 1189.619 1.5 45244 10733 2 1189.618536 595.8168 MAP7 domain-containing protein 1 OS=Homo sapiens OX=9606 GN=MAP7D1 PE=1 SV=1 6 2240.1 - 326588 - - - -0.4178 - 1.768 0.413 - 134.5 1 2 0 -0.0005 12 0 0 0 4.81E+06 3.22E+06 - - - 3.5906 0.9994 221125_WJC_METTL3_EV_vs_WT_F04.10734.10734.2 0.000143 18-Oct R.ALASFNQEER.R "sp|Q5M9Q1|NKAPL_HUMAN,sp|Q8N5F7|NKAP_HUMAN,tr|A0A494C050|A0A494C050_HUMAN" 3 1163.5571 0.98 45245 10734 2 1163.558625 582.7858 NKAP-like protein OS=Homo sapiens OX=9606 GN=NKAPL PE=1 SV=3 4.53 2240.2 - 258423 - - - 1.3098 - 2.286 0.275 - 396.9 1 2 0 0.0015 10 0 0 0 9.82E+06 1.00E+07 - - - 3.3795 0.9953 221125_WJC_METTL3_EV_vs_WT_F04.10740.10740.2 1.65 12-Aug K.R[166.11]GILTLK[136.11].Y "sp|Q6S8J3|POTEE_HUMAN,sp|P63261|ACTG_HUMAN,sp|P68133|ACTS_HUMAN,sp|P62736|ACTA_HUMAN,sp|P68032|ACTC_HUMAN,sp|P60709|ACTB_HUMAN,sp|P63267|ACTH_HUMAN,sp|A5A3E0|POTEF_HUMAN,sp|P0CG38|POTEI_HUMAN,sp|P0CG39|POTEJ_HUMAN,tr|A0A804GS07|A0A804GS07_HUMAN,tr|I3L3I0|I3L3I0_HUMAN,tr|G5E9R0|G5E9R0_HUMAN,tr|E7EVS6|E7EVS6_HUMAN,tr|A0A6Q8PFE4|A0A6Q8PFE4_HUMAN,tr|B8ZZJ2|B8ZZJ2_HUMAN,tr|J3KT65|J3KT65_HUMAN,tr|I3L3R2|I3L3R2_HUMAN,tr|K7EM38|K7EM38_HUMAN,tr|F6QUT6|F6QUT6_HUMAN,tr|C9JTX5|C9JTX5_HUMAN,tr|A0A6Q8PH58|A0A6Q8PH58_HUMAN,tr|F6UVQ4|F6UVQ4_HUMAN,tr|F8WB63|F8WB63_HUMAN,tr|I3L1U9|I3L1U9_HUMAN,tr|A0A804HKV3|A0A804HKV3_HUMAN,tr|A0A2R8Y793|A0A2R8Y793_HUMAN,tr|I3L4N8|I3L4N8_HUMAN,tr|C9JUM1|C9JUM1_HUMAN,tr|C9JZR7|C9JZR7_HUMAN,tr|C9JFL5|C9JFL5_HUMAN,tr|A0A2R8YGF8|A0A2R8YGF8_HUMAN,tr|A6NL76|A6NL76_HUMAN" 33 817.5504 0.9 45249 10740 2 817.550224 409.7825 POTE ankyrin domain family member E OS=Homo sapiens OX=9606 GN=POTEE PE=2 SV=3 11 2241 - 1.90E+06 - - - -0.2679 - 1.58 0.088 - 258.1 1 2 0 -0.0002 7 0 0 0 3.03E+07 3.36E+07 - - - 1.1403 0.8428 221125_WJC_METTL3_EV_vs_WT_F04.10743.10743.2 0.113 20-Dec K.ALQELQAAQAR.Q "sp|Q63ZY3|KANK2_HUMAN,tr|K7ERU2|K7ERU2_HUMAN" 2 1197.6466 3.08 45252 10743 2 1197.638581 599.8306 KN motif and ankyrin repeat domain-containing protein 2 OS=Homo sapiens OX=9606 GN=KANK2 PE=1 SV=1 6.05 2241.4 - 294699 - - - -6.6831 - 2.213 0.039 - 418.8 1 2 0 -0.008 11 0 0 0 7.96E+06 2.58E+06 - - - 1.4754 1 221125_WJC_METTL3_EV_vs_WT_F04.10744.10744.2 1.26E-08 24-Oct K.LGNYAGAVQDC[160.03]ER.A "sp|O43765|SGTA_HUMAN,tr|A0A7I2V588|A0A7I2V588_HUMAN,tr|K7EMD6|K7EMD6_HUMAN,tr|A0A7I2V2U2|A0A7I2V2U2_HUMAN,tr|A0A7I2V5Z3|A0A7I2V5Z3_HUMAN,tr|A0A7I2V4T9|A0A7I2V4T9_HUMAN,tr|A0A7I2V697|A0A7I2V697_HUMAN" 7 1451.6463 1.04 45253 10744 2 1451.647902 726.8304 Small glutamine-rich tetratricopeptide repeat-containing protein alpha OS=Homo sapiens OX=9606 GN=SGTA PE=1 SV=1 4.37 2241.5 - 247817 - - - 1.085 - 2.468 0.648 - 325.2 1 2 0 0.0016 13 0 0 0 2.48E+06 2.38E+06 - - - 6.1453 0.9999 221125_WJC_METTL3_EV_vs_WT_F04.10748.10748.2 0.000213 16-Nov K.MVQFEENGR[166.11].K "sp|P49368|TCPG_HUMAN,tr|Q5SZW8|Q5SZW8_HUMAN,tr|E9PRC8|E9PRC8_HUMAN,tr|B4DUR8|B4DUR8_HUMAN,tr|E9PQ35|E9PQ35_HUMAN,tr|Q5SZX6|Q5SZX6_HUMAN" 6 1118.5054 0.19 45255 10748 2 1118.505961 560.26 T-complex protein 1 subunit gamma OS=Homo sapiens OX=9606 GN=CCT3 PE=1 SV=4 4.53 2242 - 4.61E+06 - - - 0.4899 - 1.982 0.516 - 484.4 1 2 0 0.0005 9 0 0 0 1.72E+07 9.15E+07 - - - 4.8312 0.9927 221125_WJC_METTL3_EV_vs_WT_F04.10750.10750.2 0.00624 14-Aug K.LQEEMLQR.E "sp|P08670|VIME_HUMAN,tr|B0YJC5|B0YJC5_HUMAN,tr|B0YJC4|B0YJC4_HUMAN" 3 1045.5226 2.48 45257 10750 2 1045.518329 523.7686 Vimentin OS=Homo sapiens OX=9606 GN=VIM PE=1 SV=4 4.53 2242.2 - 1.96E+06 - - - -4.1137 - 1.747 0.262 - 253.1 1 2 0 -0.0043 8 0 0 0 2.20E+07 8.87E+06 - - - 2.6574 0.9993 221125_WJC_METTL3_EV_vs_WT_F04.10751.10751.2 0.00228 14-Aug K.LNWTGTSK[136.11].S "sp|O95433|AHSA1_HUMAN,tr|H0YJU2|H0YJU2_HUMAN,tr|H0YJG7|H0YJG7_HUMAN" 3 913.4749 1.11 45258 10751 2 913.47515 457.7447 Activator of 90 kDa heat shock protein ATPase homolog 1 OS=Homo sapiens OX=9606 GN=AHSA1 PE=1 SV=1 8.75 2242.2 - 1.84E+06 - - - 0.2945 - 1.591 0.305 - 184.6 1 2 0 0.0003 8 0 0 0 1.76E+07 1.59E+07 - - - 2.6941 0.9995 221125_WJC_METTL3_EV_vs_WT_F04.10753.10753.3 0.00115 Sep-36 K.ALKPANMLER.L "sp|Q9BXJ9|NAA15_HUMAN,tr|A0A0B4J1W3|A0A0B4J1W3_HUMAN" 2 1141.6278 0.27 45260 10753 3 1141.628744 381.5499 "N-alpha-acetyltransferase 15, NatA auxiliary subunit OS=Homo sapiens OX=9606 GN=NAA15 PE=1 SV=1" 8.79 2242.5 - 638558 - - - 0.8584 - 1.787 0.318 - 129.3 1 2 0 0.001 10 0 0 0 3.47E+06 1.27E+07 - - - 3.7805 0.9941 221125_WJC_METTL3_EV_vs_WT_F04.10756.10756.2 0.0317 22-Sep K.TEPTSPTPSAFK.G sp|Q86XN7|PRSR1_HUMAN 1 1261.619 0.26 45263 10756 2 1261.62145 631.8168 Proline and serine-rich protein 1 OS=Homo sapiens OX=9606 GN=PROSER1 PE=1 SV=2 5.66 2242.9 - 436008 - - - 1.9158 - 1.537 0.188 - 204.3 1 2 0 0.0024 12 0 0 0 4.13E+06 1.59E+07 - - - 1.5598 0.9999 221125_WJC_METTL3_EV_vs_WT_F04.10757.10757.2 9.01E-07 24-Nov K.LGNYAGAVQDC[160.03]ER[166.11].A "sp|O43765|SGTA_HUMAN,tr|A0A7I2V588|A0A7I2V588_HUMAN,tr|K7EMD6|K7EMD6_HUMAN,tr|A0A7I2V2U2|A0A7I2V2U2_HUMAN,tr|A0A7I2V5Z3|A0A7I2V5Z3_HUMAN,tr|A0A7I2V4T9|A0A7I2V4T9_HUMAN,tr|A0A7I2V697|A0A7I2V697_HUMAN" 7 1461.6546 1.11 45264 10757 2 1461.655446 731.8346 Small glutamine-rich tetratricopeptide repeat-containing protein alpha OS=Homo sapiens OX=9606 GN=SGTA PE=1 SV=1 4.37 2243 - 305110 - - - 0.5808 - 2.311 0.6 - 345.5 1 2 0 0.0008 13 0 0 0 2.65E+06 2.38E+06 - - - 5.6223 0.9999 221125_WJC_METTL3_EV_vs_WT_F04.10763.10763.2 0.000245 22-Dec K.GSFSDTGLGDGK.M "sp|Q9Y2W1|TR150_HUMAN,tr|A0A3B3ITZ9|A0A3B3ITZ9_HUMAN" 2 1139.5095 2.57 45269 10763 2 1139.510412 570.762 Thyroid hormone receptor-associated protein 3 OS=Homo sapiens OX=9606 GN=THRAP3 PE=1 SV=2 4.21 2243.6 - 3.74E+07 - - - 0.8161 - 2.058 0.607 - 309.2 1 2 0 0.0009 12 0 0 0 2.72E+09 1.06E+09 - - - 5.423 1 221125_WJC_METTL3_EV_vs_WT_F04.10764.10764.2 1.20E-09 22-Nov K.GSFSDTGLGDGK[136.11].M "sp|Q9Y2W1|TR150_HUMAN,tr|A0A3B3ITZ9|A0A3B3ITZ9_HUMAN" 2 1147.5237 2.57 45270 10764 2 1147.523916 574.7691 Thyroid hormone receptor-associated protein 3 OS=Homo sapiens OX=9606 GN=THRAP3 PE=1 SV=2 4.21 2243.7 - 1.72E+07 - - - 0.2039 - 2.18 0.627 - 243.2 1 2 0 0.0002 12 0 0 0 2.72E+09 1.06E+09 - - - 5.7225 0.9999 221125_WJC_METTL3_EV_vs_WT_F04.10766.10766.2 0.000942 20-Nov K.EQVANSAFVER[166.11].V "sp|P08238|HS90B_HUMAN,sp|Q58FF7|H90B3_HUMAN" 2 1258.6181 0.89 45272 10766 2 1258.617868 630.3163 Heat shock protein HSP 90-beta OS=Homo sapiens OX=9606 GN=HSP90AB1 PE=1 SV=4 4.53 2243.8 - 1.41E+06 - - - -0.2121 - 2.368 0.468 - 593.5 1 2 0 -0.0003 11 0 0 0 3.26E+08 3.65E+08 - - - 4.8296 1 221125_WJC_METTL3_EV_vs_WT_F04.10768.10768.3 7.37E-05 16/44 K.LYR[166.11]PGSVAYVSR[166.11].S sp|P53396|ACLY_HUMAN 1 1386.7523 0.72 45274 10768 3 1386.750405 463.258 ATP-citrate synthase OS=Homo sapiens OX=9606 GN=ACLY PE=1 SV=3 9.99 2244 - 1.36E+06 - - - -1.3478 - 2.672 0.465 - 387.3 1 2 0 -0.0019 12 0 0 0 2.28E+07 3.19E+07 - - - 6.448 0.9872 221125_WJC_METTL3_EV_vs_WT_F04.10770.10770.3 0.108 Aug-44 R.IYSYVVSR[166.11]PQPR[166.11].G sp|Q96CS3|FAF2_HUMAN 1 1483.805 1.01 45276 10770 3 1483.805231 495.609 FAS-associated factor 2 OS=Homo sapiens OX=9606 GN=FAF2 PE=1 SV=2 9.99 2244.2 - 1.19E+06 - - - 0.1301 - 1.427 0.191 - 77.5 1 2 0 0.0002 12 0 0 0 1.11E+07 1.10E+07 - - - 1.655 0.9987 221125_WJC_METTL3_EV_vs_WT_F04.10771.10771.2 0.457 12-Nov R.HLQLAIR[166.11].N "sp|P16104|H2AX_HUMAN,sp|Q9BTM1|H2AJ_HUMAN,sp|Q93077|H2A1C_HUMAN,sp|Q99878|H2A1J_HUMAN,sp|Q16777|H2A2C_HUMAN,sp|Q96QV6|H2A1A_HUMAN,sp|P0C0S5|H2AZ_HUMAN,sp|P04908|H2A1B_HUMAN,sp|P20671|H2A1D_HUMAN,sp|P0C0S8|H2A1_HUMAN,sp|Q6FI13|H2A2A_HUMAN,sp|Q96KK5|H2A1H_HUMAN,sp|Q71UI9|H2AV_HUMAN,sp|Q7L7L0|H2A3_HUMAN,tr|C9J386|C9J386_HUMAN,tr|A0A0U1RR32|A0A0U1RR32_HUMAN,tr|A0A0U1RRH7|A0A0U1RRH7_HUMAN,tr|A0A3B3IS11|A0A3B3IS11_HUMAN,tr|H0YFX9|H0YFX9_HUMAN,tr|C9J0D1|C9J0D1_HUMAN,tr|A0A494C189|A0A494C189_HUMAN" 21 859.5267 1.12 45277 10771 2 859.526991 430.7706 Histone H2AX OS=Homo sapiens OX=9606 GN=H2AX PE=1 SV=2 9.76 2244.3 - 1.01E+06 - - - 0.2909 - 1.936 0.145 - 476.6 1 2 0 0.0003 7 0 0 0 1.02E+09 9.11E+08 - - - 2.2051 0.9996 221125_WJC_METTL3_EV_vs_WT_F04.10776.10776.2 0.00353 20-Oct R.IVEPPENIQEK[136.11].L "sp|A5YKK6|CNOT1_HUMAN,tr|H3BVC9|H3BVC9_HUMAN" 2 1302.6911 1.06 45282 10776 2 1302.690259 652.3528 CCR4-NOT transcription complex subunit 1 OS=Homo sapiens OX=9606 GN=CNOT1 PE=1 SV=2 4.25 2244.9 - 421859 - - - -0.6318 - 1.838 0.36 - 301.2 1 2 0 -0.0008 11 0 0 0 8.49E+06 8.02E+06 - - - 3.3463 1 221125_WJC_METTL3_EV_vs_WT_F04.10777.10777.2 2.10E-08 22-Sep K.TFTC[160.03]TAAYPESK.T "sp|P01876|IGHA1_HUMAN,tr|A0A286YEY1|A0A286YEY1_HUMAN" 2 1374.6126 91.07 45283 10777 2 1374.604598 688.3136 Immunoglobulin heavy constant alpha 1 OS=Homo sapiens OX=9606 GN=IGHA1 PE=1 SV=2 5.66 2245 - 386008 - - - -5.7973 - 2.05 0.677 - 176.1 1 2 0 -0.008 12 0 0 0 2.91E+07 3.20E+05 - - - 5.9276 0.9997 221125_WJC_METTL3_EV_vs_WT_F04.10778.10778.2 0.0288 20-Sep R.IVEPPENIQEK.L "sp|A5YKK6|CNOT1_HUMAN,tr|H3BVC9|H3BVC9_HUMAN" 2 1294.6769 1.03 45284 10778 2 1294.67676 648.3457 CCR4-NOT transcription complex subunit 1 OS=Homo sapiens OX=9606 GN=CNOT1 PE=1 SV=2 4.25 2245.2 - 375250 - - - -0.0942 - 1.797 0.393 - 157.8 1 2 0 -0.0001 11 0 0 0 7.96E+06 7.74E+06 - - - 3.5292 1 221125_WJC_METTL3_EV_vs_WT_F04.10779.10779.2 1.09E-05 14/26 K.AQAELVGTADEATR.A sp|P30049|ATPD_HUMAN 1 1430.7001 2.71 45285 10779 2 1430.699254 716.3573 "ATP synthase subunit delta, mitochondrial OS=Homo sapiens OX=9606 GN=ATP5F1D PE=1 SV=2" 4.14 2245.3 - 311489 - - - -0.6172 - 2.945 0.605 - 627.5 1 2 0 -0.0009 14 0 0 0 2.29E+07 8.45E+06 - - - 6.2197 0.9999 221125_WJC_METTL3_EV_vs_WT_F04.10783.10783.2 3.19E-05 20-Nov K.EQVANSAFVER.V "sp|P08238|HS90B_HUMAN,sp|Q58FF7|H90B3_HUMAN" 2 1248.6099 0.89 45287 10783 2 1248.610013 625.3122 Heat shock protein HSP 90-beta OS=Homo sapiens OX=9606 GN=HSP90AB1 PE=1 SV=4 4.53 2245.8 - 5.51E+06 - - - 0.1185 - 2.131 0.517 - 566.3 1 2 0 0.0001 11 0 0 0 3.26E+08 3.65E+08 - - - 4.9063 0.9947 221125_WJC_METTL3_EV_vs_WT_F04.10784.10784.2 0.0973 12-Nov R.HLQLAIR.N "sp|P16104|H2AX_HUMAN,sp|Q9BTM1|H2AJ_HUMAN,sp|Q93077|H2A1C_HUMAN,sp|Q99878|H2A1J_HUMAN,sp|Q16777|H2A2C_HUMAN,sp|Q96QV6|H2A1A_HUMAN,sp|P0C0S5|H2AZ_HUMAN,sp|P04908|H2A1B_HUMAN,sp|P20671|H2A1D_HUMAN,sp|P0C0S8|H2A1_HUMAN,sp|Q6FI13|H2A2A_HUMAN,sp|Q96KK5|H2A1H_HUMAN,sp|Q71UI9|H2AV_HUMAN,sp|Q7L7L0|H2A3_HUMAN,tr|C9J386|C9J386_HUMAN,tr|A0A0U1RR32|A0A0U1RR32_HUMAN,tr|A0A0U1RRH7|A0A0U1RRH7_HUMAN,tr|A0A3B3IS11|A0A3B3IS11_HUMAN,tr|H0YFX9|H0YFX9_HUMAN,tr|C9J0D1|C9J0D1_HUMAN,tr|A0A494C189|A0A494C189_HUMAN" 21 849.5185 1.12 45288 10784 2 849.517372 425.7665 Histone H2AX OS=Homo sapiens OX=9606 GN=H2AX PE=1 SV=2 9.76 2245.9 - 5.11E+06 - - - -1.2937 - 1.71 0.075 - 470.9 1 2 0 -0.0011 7 0 0 0 1.02E+09 9.11E+08 - - - 1.2945 0.9995 221125_WJC_METTL3_EV_vs_WT_F04.10786.10786.2 0.175 20-Nov R.SLGPSLATDK[136.11]S.- sp|Q9H3N1|TMX1_HUMAN 1 1082.5699 1.04 45290 10786 2 1082.570154 542.2922 Thioredoxin-related transmembrane protein 1 OS=Homo sapiens OX=9606 GN=TMX1 PE=1 SV=1 5.55 2246 - 2.02E+06 - - - 0.2309 - 1.813 0.333 - 238.2 1 2 0 0.0003 11 0 0 0 3.03E+07 2.92E+07 - - - 3.11 0.9998 221125_WJC_METTL3_EV_vs_WT_F04.10787.10787.2 3.88E-05 22-Nov K.ITANEDPPVISK.R sp|Q5VT06|CE350_HUMAN 1 1282.6769 2.55 45291 10787 2 1282.676453 642.3457 Centrosome-associated protein 350 OS=Homo sapiens OX=9606 GN=CEP350 PE=1 SV=1 4.37 2246.1 - 1.95E+06 - - - -0.3345 - 2.412 0.405 - 291.8 1 2 0 -0.0004 12 0 0 0 2.70E+07 1.06E+07 - - - 4.3488 1 221125_WJC_METTL3_EV_vs_WT_F04.10788.10788.3 4.94E-05 16/44 K.LYRPGSVAYVSR.S sp|P53396|ACLY_HUMAN 1 1366.7357 0.72 45292 10788 3 1366.734878 456.5859 ATP-citrate synthase OS=Homo sapiens OX=9606 GN=ACLY PE=1 SV=3 9.99 2246.2 - 1.82E+06 - - - -0.6263 - 2.806 0.466 - 422.2 1 2 0 -0.0009 12 0 0 0 2.29E+07 3.19E+07 - - - 6.5951 0.9999 221125_WJC_METTL3_EV_vs_WT_F04.10791.10791.2 2.55E-05 22-Oct K.GLSEDTTEETLK[136.11].E "sp|P19338|NUCL_HUMAN,tr|A0A7I2V699|A0A7I2V699_HUMAN,tr|A0A7I2V2U7|A0A7I2V2U7_HUMAN,tr|A0A7I2V3F3|A0A7I2V3F3_HUMAN,tr|A0A7I2V428|A0A7I2V428_HUMAN,tr|H7BY16|H7BY16_HUMAN,tr|A0A7I2V5M5|A0A7I2V5M5_HUMAN,tr|C9JLB1|C9JLB1_HUMAN" 8 1329.6391 1.09 45295 10791 2 1329.638125 665.8268 Nucleolin OS=Homo sapiens OX=9606 GN=NCL PE=1 SV=3 4 2246.6 - 932801 - - - -0.7378 - 2.175 0.539 - 262.8 1 2 0 -0.001 12 0 0 0 1.21E+08 1.11E+08 - - - 5.0662 0.9999 221125_WJC_METTL3_EV_vs_WT_F04.10793.10793.2 0.000106 22-Dec K.GLSEDTTEETLK.E "sp|P19338|NUCL_HUMAN,tr|A0A7I2V699|A0A7I2V699_HUMAN,tr|A0A7I2V2U7|A0A7I2V2U7_HUMAN,tr|A0A7I2V3F3|A0A7I2V3F3_HUMAN,tr|A0A7I2V428|A0A7I2V428_HUMAN,tr|H7BY16|H7BY16_HUMAN,tr|A0A7I2V5M5|A0A7I2V5M5_HUMAN,tr|C9JLB1|C9JLB1_HUMAN" 8 1321.6249 1.09 45297 10793 2 1321.624193 661.8197 Nucleolin OS=Homo sapiens OX=9606 GN=NCL PE=1 SV=3 4 2246.8 - 773120 - - - -0.5395 - 2.534 0.555 - 443.7 1 2 0 -0.0007 12 0 0 0 1.21E+08 1.11E+08 - - - 5.5865 0.9992 221125_WJC_METTL3_EV_vs_WT_F04.10794.10794.2 2.44E-06 13/26 K.AQAELVGTADEATR[166.11].A sp|P30049|ATPD_HUMAN 1 1440.7084 2.71 45298 10794 2 1440.703448 721.3615 "ATP synthase subunit delta, mitochondrial OS=Homo sapiens OX=9606 GN=ATP5F1D PE=1 SV=2" 4.14 2247 - 508441 - - - -3.4421 - 2.816 0.42 - 603 1 2 0 -0.005 14 0 0 0 2.29E+07 8.45E+06 - - - 4.7396 0.9995 221125_WJC_METTL3_EV_vs_WT_F04.10795.10795.3 0.0105 Nov-52 K.AQAELVGTADEATR.A sp|P30049|ATPD_HUMAN 1 1430.7001 0.96 45299 10795 3 1430.701736 477.9073 "ATP synthase subunit delta, mitochondrial OS=Homo sapiens OX=9606 GN=ATP5F1D PE=1 SV=2" 4.14 2247.1 - 469051 - - - 1.1176 - 1.824 0.335 - 130.9 1 2 0 0.0016 14 0 0 0 5.69E+06 5.95E+06 - - - 3.8717 0.992 221125_WJC_METTL3_EV_vs_WT_F04.10802.10802.3 0.0106 16/44 M.AIEHADFAGVER[166.11].L "sp|P78371|TCPB_HUMAN,tr|F8VQ14|F8VQ14_HUMAN,tr|F5GWF6|F5GWF6_HUMAN" 3 1323.6447 0.49 45304 10802 3 1323.64427 442.2222 T-complex protein 1 subunit beta OS=Homo sapiens OX=9606 GN=CCT2 PE=1 SV=4 4.65 2247.9 - 3.18E+06 - - - -0.3128 - 2.527 0.39 - 448.3 1 1 0 -0.0004 12 0 0 0 2.49E+07 5.06E+07 - - - 5.4576 0.9387 221125_WJC_METTL3_EV_vs_WT_F04.10804.10804.2 0.00365 16-Jul K.ETAENYLGH.T "sp|P38646|GRP75_HUMAN,tr|H0Y8K0|H0Y8K0_HUMAN,tr|A0A7I2V2S7|A0A7I2V2S7_HUMAN,tr|A0A7I2V2G2|A0A7I2V2G2_HUMAN,tr|A0A7I2V3F7|A0A7I2V3F7_HUMAN,tr|A0A7I2YQB2|A0A7I2YQB2_HUMAN,tr|D6RCD7|D6RCD7_HUMAN" 7 1032.4512 - 45306 10804 2 1032.451974 517.2329 "Stress-70 protein, mitochondrial OS=Homo sapiens OX=9606 GN=HSPA9 PE=1 SV=2" 4.51 2248 - 1.65E+06 - - - 0.7119 - 1.293 0.359 - 151.4 1 1 0 0.0007 9 0 0 0 - - - - - 2.4358 0.9996 221125_WJC_METTL3_EV_vs_WT_F04.10805.10805.2 0.0875 14-Dec K.HILILQNK.L "sp|Q2VIR3|IF2GL_HUMAN,sp|P41091|IF2G_HUMAN" 2 977.6022 0.86 45307 10805 2 977.602375 489.8084 Eukaryotic translation initiation factor 2 subunit 3B OS=Homo sapiens OX=9606 GN=EIF2S3B PE=2 SV=2 8.76 2248.1 - 1.38E+06 - - - 0.178 - 2.031 0.293 - 659 1 2 0 0.0002 8 0 0 0 3.47E+07 4.03E+07 - - - 3.3419 0.9876 221125_WJC_METTL3_EV_vs_WT_F04.10806.10806.2 0.426 22-Nov K.ITANEDPPVISK[136.11].R sp|Q5VT06|CE350_HUMAN 1 1290.6911 2.58 45308 10806 2 1290.688304 646.3528 Centrosome-associated protein 350 OS=Homo sapiens OX=9606 GN=CEP350 PE=1 SV=1 4.37 2248.3 - 877279 - - - -2.1523 - 1.472 0.138 - 127.9 1 2 0 -0.0028 12 0 0 0 2.70E+07 1.05E+07 - - - 1.0767 0.9997 221125_WJC_METTL3_EV_vs_WT_F04.10809.10809.2 0.000657 13/26 R.QLEEPGAGTPSPVR[166.11].L "sp|Q63ZY6|NSN5C_HUMAN,sp|Q96P11|NSUN5_HUMAN" 2 1446.7342 0.99 45311 10809 2 1446.736162 724.3744 Putative methyltransferase NSUN5C OS=Homo sapiens OX=9606 GN=NSUN5P2 PE=5 SV=2 4.53 2248.6 - 425869 - - - 1.3375 - 2.265 0.409 - 264.8 1 2 0 0.0019 14 0 0 0 9.59E+06 9.71E+06 - - - 4.1129 0.9998 221125_WJC_METTL3_EV_vs_WT_F04.10814.10814.2 0.00332 14-Oct K.HILILQNK[136.11].L "sp|Q2VIR3|IF2GL_HUMAN,sp|P41091|IF2G_HUMAN" 2 985.6164 0.88 45314 10814 2 985.614985 493.8155 Eukaryotic translation initiation factor 2 subunit 3B OS=Homo sapiens OX=9606 GN=EIF2S3B PE=2 SV=2 8.76 2249.3 - 3.05E+06 - - - -1.4367 - 2.091 0.457 - 395 1 2 0 -0.0014 8 0 0 0 3.54E+07 4.04E+07 - - - 4.6407 0.968 221125_WJC_METTL3_EV_vs_WT_F04.10815.10815.2 0.583 16-Nov K.AQLFETSSK.T "sp|Q969Q5|RAB24_HUMAN,tr|F8W8H5|F8W8H5_HUMAN" 2 1009.508 4.89 45315 10815 2 1009.511882 505.7613 Ras-related protein Rab-24 OS=Homo sapiens OX=9606 GN=RAB24 PE=1 SV=1 6.05 2249.4 - 983770 - - - 3.8197 - 1.411 0.168 - 290 1 2 0 0.0039 9 0 0 0 2.37E+07 4.84E+06 - - - 1.2767 0.9995 221125_WJC_METTL3_EV_vs_WT_F04.10817.10817.2 0.000217 15/24 K.SAGLEQPTDPVAR.D "sp|O75410|TACC1_HUMAN,tr|E7EVI4|E7EVI4_HUMAN,tr|E5RFM9|E5RFM9_HUMAN,tr|R4GMT7|R4GMT7_HUMAN,tr|H0YAY0|H0YAY0_HUMAN,tr|E7ET87|E7ET87_HUMAN" 6 1339.6732 1.34 45317 10817 2 1339.676826 670.8439 Transforming acidic coiled-coil-containing protein 1 OS=Homo sapiens OX=9606 GN=TACC1 PE=1 SV=2 4.37 2249.7 - 975267 - - - 2.7119 - 2.735 0.437 - 635.1 1 2 0 0.0036 13 0 0 0 5.69E+07 4.26E+07 - - - 4.8498 0.9994 221125_WJC_METTL3_EV_vs_WT_F04.10819.10819.2 0.0105 14/26 R.QLEEPGAGTPSPVR.L "sp|Q63ZY6|NSN5C_HUMAN,sp|Q96P11|NSUN5_HUMAN" 2 1436.726 0.99 45319 10819 2 1436.725457 719.3703 Putative methyltransferase NSUN5C OS=Homo sapiens OX=9606 GN=NSUN5P2 PE=5 SV=2 4.53 2249.9 - 814483 - - - -0.348 - 2.12 0.253 - 401.9 1 2 0 -0.0005 14 0 0 0 9.59E+06 9.71E+06 - - - 2.7951 0.981 221125_WJC_METTL3_EV_vs_WT_F04.10820.10820.3 0.00265 Dec-36 R.ALEFAPAC[160.03]HR[166.11].F "sp|Q99615|DNJC7_HUMAN,tr|A0A6I8PRZ0|A0A6I8PRZ0_HUMAN,tr|A0A6I8PLE7|A0A6I8PLE7_HUMAN,tr|A0A6I8PR89|A0A6I8PR89_HUMAN,tr|A0A6I8PIK4|A0A6I8PIK4_HUMAN,tr|A0A6I8PUC2|A0A6I8PUC2_HUMAN,tr|A0A6I8PS32|A0A6I8PS32_HUMAN,tr|K7EPP7|K7EPP7_HUMAN,tr|A0A6I8PUD4|A0A6I8PUD4_HUMAN,tr|K7EIH8|K7EIH8_HUMAN,tr|K7ER44|K7ER44_HUMAN,tr|A0A6I8PU73|A0A6I8PU73_HUMAN,tr|K7EK03|K7EK03_HUMAN,tr|A0A6I8PU89|A0A6I8PU89_HUMAN" 14 1180.5687 0 45320 10820 3 1181.568196 394.5302 DnaJ homolog subfamily C member 7 OS=Homo sapiens OX=9606 GN=DNAJC7 PE=1 SV=2 6.78 2250.1 - 797614 - - - 846.6369 - 1.867 0.425 - 256.1 1 2 0 0.9995 10 0 0 0 1.00E+05 2.21E+07 - - - 4.8248 0.9999 221125_WJC_METTL3_EV_vs_WT_F04.10826.10826.2 0.000238 13/20 K.TEVPGSVTEYK.V "sp|P34949|MPI_HUMAN,tr|H3BPB8|H3BPB8_HUMAN,tr|F5GX71|F5GX71_HUMAN" 3 1208.5925 1.09 45325 10826 2 1208.591735 605.3035 Mannose-6-phosphate isomerase OS=Homo sapiens OX=9606 GN=MPI PE=1 SV=2 4.53 2250.8 - 1.39E+06 - - - -0.6197 - 2.353 0.507 - 452.5 1 2 0 -0.0007 11 0 0 0 3.21E+07 2.93E+07 - - - 5.1003 1 221125_WJC_METTL3_EV_vs_WT_F04.10828.10828.2 1.67E-06 22-Dec K.SVQVNGAATELR.K "sp|Q92615|LAR4B_HUMAN,tr|A0A087X183|A0A087X183_HUMAN" 2 1243.6521 1.25 45326 10828 2 1243.6493 622.8333 La-related protein 4B OS=Homo sapiens OX=9606 GN=LARP4B PE=1 SV=3 5.72 2251 - 4.10E+06 - - - -2.2225 - 2.622 0.565 - 550.7 1 2 0 -0.0028 12 0 0 0 2.73E+08 2.19E+08 - - - 5.7495 0.9958 221125_WJC_METTL3_EV_vs_WT_F04.10829.10829.3 1.56E-05 14/44 M.AIEHADFAGVER.L "sp|P78371|TCPB_HUMAN,tr|F8VQ14|F8VQ14_HUMAN,tr|F5GWF6|F5GWF6_HUMAN" 3 1313.6364 0.5 45327 10829 3 1313.634258 438.8861 T-complex protein 1 subunit beta OS=Homo sapiens OX=9606 GN=CCT2 PE=1 SV=4 4.65 2251.1 - 2.77E+06 - - - -1.6412 - 2.709 0.475 - 356.4 1 1 0 -0.0022 12 0 0 0 2.49E+07 5.04E+07 - - - 6.5976 0.9956 221125_WJC_METTL3_EV_vs_WT_F04.10831.10831.2 0.00984 18-Nov R.QIMEEC[160.03]ENLK.L "sp|Q15643|TRIPB_HUMAN,tr|H0YJ97|H0YJ97_HUMAN" 2 1292.5741 1.21 45329 10831 2 1292.570625 647.2943 Thyroid receptor-interacting protein 11 OS=Homo sapiens OX=9606 GN=TRIP11 PE=1 SV=3 4.25 2251.3 - 1.09E+06 - - - -2.6675 - 1.451 0.282 - 156.2 1 2 0 -0.0034 10 0 0 0 1.71E+07 1.41E+07 - - - 2.1618 0.9996 221125_WJC_METTL3_EV_vs_WT_F04.10832.10832.2 0.0702 13/22 K.QPAPTTIGGLNK[136.11].K "sp|P27816|MAP4_HUMAN,tr|E7EVA0|E7EVA0_HUMAN,tr|H7C4C5|H7C4C5_HUMAN,tr|A0A804HKE7|A0A804HKE7_HUMAN,tr|B5MEG9|B5MEG9_HUMAN" 5 1203.6703 0.48 45330 10832 2 1203.667111 602.8424 Microtubule-associated protein 4 OS=Homo sapiens OX=9606 GN=MAP4 PE=1 SV=3 8.75 2251.4 - 703803 - - - -2.6386 - 2.393 0.457 - 673.9 1 2 0 -0.0032 12 0 0 0 7.72E+06 1.60E+07 - - - 4.7112 0.9955 221125_WJC_METTL3_EV_vs_WT_F04.10833.10833.2 0.31 16-Aug K.EQGIQDPIK.G "sp|Q8IWX8|CHERP_HUMAN,tr|J3QK89|J3QK89_HUMAN" 2 1026.5346 1.26 45331 10833 2 1026.532359 514.2746 Calcium homeostasis endoplasmic reticulum protein OS=Homo sapiens OX=9606 GN=CHERP PE=1 SV=3 4.37 2251.5 - 588457 - - - -2.1587 - 1.411 0.245 - 234.6 1 2 0 -0.0022 9 0 0 0 1.46E+07 1.16E+07 - - - 1.8459 0.9995 221125_WJC_METTL3_EV_vs_WT_F04.10840.10840.2 0.0115 18-Nov R.QIMEEC[160.03]ENLK[136.11].L "sp|Q15643|TRIPB_HUMAN,tr|H0YJ97|H0YJ97_HUMAN" 2 1300.5883 1.21 45336 10840 2 1300.585599 651.3014 Thyroid receptor-interacting protein 11 OS=Homo sapiens OX=9606 GN=TRIP11 PE=1 SV=3 4.25 2252.4 - 920620 - - - -2.056 - 1.81 0.437 - 359.1 1 2 0 -0.0027 10 0 0 0 1.71E+07 1.41E+07 - - - 3.924 0.9998 221125_WJC_METTL3_EV_vs_WT_F04.10842.10842.3 2.32E-05 15/44 K.LAVIASHIQESR[166.11].F "sp|Q13889|TF2H3_HUMAN,tr|F5H4K7|F5H4K7_HUMAN,tr|F5GXG6|F5GXG6_HUMAN,tr|F5GWD3|F5GWD3_HUMAN,tr|F5H6X0|F5H6X0_HUMAN,tr|F5GX35|F5GX35_HUMAN" 6 1332.7389 0.71 45338 10842 3 1332.735771 445.2536 General transcription factor IIH subunit 3 OS=Homo sapiens OX=9606 GN=GTF2H3 PE=1 SV=2 6.75 2252.7 - 565953 - - - -2.3621 - 2.622 0.375 - 277.8 1 2 0 -0.0031 12 0 0 0 3.89E+06 5.44E+06 - - - 5.3919 0.9954 221125_WJC_METTL3_EV_vs_WT_F04.10847.10847.2 0.195 14-Jul K.QPTIFQNK.K "sp|P62280|RS11_HUMAN,tr|M0QZC5|M0QZC5_HUMAN,tr|M0R1H6|M0R1H6_HUMAN" 3 974.5185 1 45341 10847 2 974.516895 488.2665 40S ribosomal protein S11 OS=Homo sapiens OX=9606 GN=RPS11 PE=1 SV=3 8.75 2253.4 - 3.23E+06 - - - -1.6788 - 1.409 0.203 - 260.2 1 2 0 -0.0016 8 0 0 0 1.41E+09 1.41E+09 - - - 1.574 0.9993 221125_WJC_METTL3_EV_vs_WT_F04.10848.10848.3 0.00295 Dec-36 R.IHDPQLLTER[166.11].A "sp|P14868|SYDC_HUMAN,tr|H7BZ35|H7BZ35_HUMAN" 2 1230.6596 0.98 45342 10848 3 1230.654403 411.2271 "Aspartate--tRNA ligase, cytoplasmic OS=Homo sapiens OX=9606 GN=DARS1 PE=1 SV=2" 5.32 2253.4 - 1.39E+06 - - - -4.2278 - 2.3 0.401 - 237.4 1 2 0 -0.0052 10 0 0 0 3.50E+07 3.57E+07 - - - 5.4418 0.997 221125_WJC_METTL3_EV_vs_WT_F04.10850.10850.2 0.00663 16-Oct K.TPEDVIC[160.03]ER[166.11].S sp|Q86XL3|ANKL2_HUMAN 1 1127.5156 4.34 45344 10850 2 1127.511931 564.7651 Ankyrin repeat and LEM domain-containing protein 2 OS=Homo sapiens OX=9606 GN=ANKLE2 PE=1 SV=4 4.14 2253.7 - 833721 - - - -3.2931 - 1.721 0.315 - 339.6 1 2 0 -0.0037 9 0 0 0 5.16E+07 1.19E+07 - - - 2.9371 0.9999 221125_WJC_METTL3_EV_vs_WT_F04.10851.10851.3 1.07E-05 17/44 K.SVQVNGAATELR.K "sp|Q92615|LAR4B_HUMAN,tr|A0A087X183|A0A087X183_HUMAN" 2 1243.6521 1.2 45345 10851 3 1243.649297 415.558 La-related protein 4B OS=Homo sapiens OX=9606 GN=LARP4B PE=1 SV=3 5.72 2253.8 - 793096 - - - -2.2249 - 2.586 0.445 - 396.3 1 2 0 -0.0028 12 0 0 0 1.30E+07 1.08E+07 - - - 6.1341 0.9989 221125_WJC_METTL3_EV_vs_WT_F04.10852.10852.2 0.000551 18-Oct R.NEEEVNNLVK[136.11].S "sp|Q9BY49|PECR_HUMAN,tr|B4DJS2|B4DJS2_HUMAN" 2 1194.5972 1.42 45346 10852 2 1194.592889 598.3059 Peroxisomal trans-2-enoyl-CoA reductase OS=Homo sapiens OX=9606 GN=PECR PE=1 SV=2 4.25 2254 - 761605 - - - -3.5928 - 2.13 0.436 - 478 1 2 0 -0.0043 10 0 0 0 5.13E+07 3.61E+07 - - - 4.3705 0.9997 221125_WJC_METTL3_EV_vs_WT_F04.10857.10857.3 0.0103 Dec-36 R.IHDPQLLTER.A "sp|P14868|SYDC_HUMAN,tr|H7BZ35|H7BZ35_HUMAN" 2 1220.6513 0.03 45349 10857 3 1220.648344 407.8911 "Aspartate--tRNA ligase, cytoplasmic OS=Homo sapiens OX=9606 GN=DARS1 PE=1 SV=2" 5.32 2254.6 - 1.73E+06 - - - -2.4512 - 2.389 0.355 - 231.3 1 2 0 -0.003 10 0 0 0 4.81E+07 1.62E+09 - - - 5.0404 0.9998 221125_WJC_METTL3_EV_vs_WT_F04.10858.10858.2 0.000584 18-Sep R.FQTEIQTVNK.Q "sp|P14868|SYDC_HUMAN,tr|H7BZ35|H7BZ35_HUMAN" 2 1206.6245 1.77 45350 10858 2 1206.624929 604.3195 "Aspartate--tRNA ligase, cytoplasmic OS=Homo sapiens OX=9606 GN=DARS1 PE=1 SV=2" 6 2254.6 - 1.63E+06 - - - 0.3953 - 1.939 0.449 - 205.3 1 2 0 0.0005 10 0 0 0 4.11E+07 2.33E+07 - - - 4.2055 0.9995 221125_WJC_METTL3_EV_vs_WT_F04.10859.10859.2 0.00258 14-Nov K.NDIHTLLK.D "sp|O43324|MCA3_HUMAN,tr|C9J1V9|C9J1V9_HUMAN,tr|H0YAL7|H0YAL7_HUMAN,tr|D6RBD7|D6RBD7_HUMAN,tr|H0YAH9|H0YAH9_HUMAN" 5 952.5342 0.96 45351 10859 2 952.533331 477.2744 Eukaryotic translation elongation factor 1 epsilon-1 OS=Homo sapiens OX=9606 GN=EEF1E1 PE=1 SV=1 6.74 2254.8 - 1.02E+06 - - - -0.8924 - 1.765 0.337 - 429.4 1 2 0 -0.0008 8 0 0 0 1.32E+07 1.37E+07 - - - 3.2433 0.9998 221125_WJC_METTL3_EV_vs_WT_F04.10860.10860.3 0.0299 14/44 K.SVQVNGAATELR[166.11].K "sp|Q92615|LAR4B_HUMAN,tr|A0A087X183|A0A087X183_HUMAN" 2 1253.6603 1.24 45352 10860 3 1253.660384 418.8941 La-related protein 4B OS=Homo sapiens OX=9606 GN=LARP4B PE=1 SV=3 5.72 2254.9 - 982117 - - - 0.0399 - 2.317 0.327 - 266.1 1 2 0 0.0001 12 0 0 0 1.35E+07 1.09E+07 - - - 4.5148 0.9999 221125_WJC_METTL3_EV_vs_WT_F04.10861.10861.2 9.24E-05 16-Nov K.TPEDVIC[160.03]ER.S sp|Q86XL3|ANKL2_HUMAN 1 1117.5074 2.93 45353 10861 2 1117.506933 559.761 Ankyrin repeat and LEM domain-containing protein 2 OS=Homo sapiens OX=9606 GN=ANKLE2 PE=1 SV=4 4.14 2255 - 743643 - - - -0.3946 - 2.158 0.505 - 710.5 1 2 0 -0.0004 9 0 0 0 5.70E+07 1.95E+07 - - - 4.9961 0.9994 221125_WJC_METTL3_EV_vs_WT_F04.10862.10862.2 0.0276 14-Oct R.QGWQNSIR.H "sp|Q12952|FOXL1_HUMAN,sp|P55316|FOXG1_HUMAN,sp|Q12948|FOXC1_HUMAN,sp|Q99958|FOXC2_HUMAN,tr|M0R279|M0R279_HUMAN" 5 987.4886 1.61 45354 10862 2 987.489009 494.7516 Forkhead box protein L1 OS=Homo sapiens OX=9606 GN=FOXL1 PE=2 SV=2 9.75 2255.1 - 1.83E+06 - - - 0.3868 - 1.583 0.328 - 393.2 1 2 0 0.0004 8 0 0 0 1.17E+08 7.25E+07 - - - 2.8488 0.9988 221125_WJC_METTL3_EV_vs_WT_F04.10863.10863.2 0.00538 16-Jul R.FFVSSSQGR[166.11].S "sp|P35613|BASI_HUMAN,tr|A0A7P0T8A7|A0A7P0T8A7_HUMAN,tr|A0A087WUV8|A0A087WUV8_HUMAN,tr|A0A7P0TA85|A0A7P0TA85_HUMAN,tr|A0A7P0TB04|A0A7P0TB04_HUMAN,tr|R4GMX5|R4GMX5_HUMAN,tr|I3L192|I3L192_HUMAN" 7 1023.5013 0.66 45355 10863 2 1023.4989 512.7579 Basigin OS=Homo sapiens OX=9606 GN=BSG PE=1 SV=2 9.75 2255.2 - 577879 - - - -2.3586 - 1.593 0.377 - 118.6 1 2 0 -0.0024 9 0 0 0 7.14E+06 1.08E+07 - - - 3.1718 0.9999 221125_WJC_METTL3_EV_vs_WT_F04.10871.10871.2 0.00257 13/24 K.SAGLEQPTDPVAR[166.11].D "sp|O75410|TACC1_HUMAN,tr|E7EVI4|E7EVI4_HUMAN,tr|E5RFM9|E5RFM9_HUMAN,tr|R4GMT7|R4GMT7_HUMAN,tr|H0YAY0|H0YAY0_HUMAN,tr|E7ET87|E7ET87_HUMAN" 6 1349.6815 1.34 45362 10871 2 1349.679887 675.848 Transforming acidic coiled-coil-containing protein 1 OS=Homo sapiens OX=9606 GN=TACC1 PE=1 SV=2 4.37 2256.3 - 2.52E+06 - - - -1.1677 - 2.559 0.527 - 515.9 1 2 0 -0.0016 13 0 0 0 5.68E+07 4.25E+07 - - - 5.3445 0.9998 221125_WJC_METTL3_EV_vs_WT_F04.10873.10873.2 0.000324 18-Nov R.VLTVINQTQK[136.11].E "sp|P42766|RL35_HUMAN,tr|F2Z388|F2Z388_HUMAN" 2 1150.6801 0.59 45363 10873 2 1150.679341 576.3473 60S ribosomal protein L35 OS=Homo sapiens OX=9606 GN=RPL35 PE=1 SV=2 8.72 2256.5 - 6.48E+06 - - - -0.6796 - 2.13 0.445 - 456.3 1 2 0 -0.0008 10 0 0 0 4.59E+07 7.77E+07 - - - 4.4381 0.9992 221125_WJC_METTL3_EV_vs_WT_F04.10874.10874.2 2.77 14-Oct R.QGWQNSIR[166.11].H "sp|Q12952|FOXL1_HUMAN,sp|P55316|FOXG1_HUMAN,sp|Q12948|FOXC1_HUMAN,sp|Q99958|FOXC2_HUMAN,tr|M0R279|M0R279_HUMAN" 5 997.4969 1.61 45364 10874 2 997.494071 499.7557 Forkhead box protein L1 OS=Homo sapiens OX=9606 GN=FOXL1 PE=2 SV=2 9.75 2256.6 - 2.04E+06 - - - -2.8331 - 1.876 0.421 - 482.8 1 2 0 -0.0028 8 0 0 0 1.17E+08 7.25E+07 - - - 4.0471 0.9981 221125_WJC_METTL3_EV_vs_WT_F04.10879.10879.2 0.112 20-Sep R.SVAQYTGGIAK[136.11].L sp|Q10713|MPPA_HUMAN 1 1101.591 0.63 45369 10879 2 1101.591153 551.8028 Mitochondrial-processing peptidase subunit alpha OS=Homo sapiens OX=9606 GN=PMPCA PE=1 SV=2 8.31 2257.1 - 681014 - - - 0.1625 - 1.613 0.204 - 202.7 1 2 0 0.0002 11 0 0 0 3.67E+06 5.87E+06 - - - 1.841 0.9998 221125_WJC_METTL3_EV_vs_WT_F04.10880.10880.3 0.00272 13/44 K.VAEDFVSPEHVK.H "sp|Q9Y4C1|KDM3A_HUMAN,sp|Q7LBC6|KDM3B_HUMAN" 2 1355.6721 0.98 45370 10880 3 1355.672974 452.898 Lysine-specific demethylase 3A OS=Homo sapiens OX=9606 GN=KDM3A PE=1 SV=4 4.65 2257.3 - 626986 - - - 0.6218 - 1.975 0.366 - 157 1 2 0 0.0008 12 0 0 0 8.63E+06 8.77E+06 - - - 4.5067 0.9847 221125_WJC_METTL3_EV_vs_WT_F04.10881.10881.2 0.233 18-Oct L.KVGLQVVAVK.A "sp|P10809|CH60_HUMAN,tr|A0A7I2V2X6|A0A7I2V2X6_HUMAN,tr|A0A7I2YQK6|A0A7I2YQK6_HUMAN,tr|A0A7I2V599|A0A7I2V599_HUMAN,tr|A0A7I2V5M1|A0A7I2V5M1_HUMAN" 5 1039.6754 1.25 45371 10881 2 1039.674712 520.845 "60 kDa heat shock protein, mitochondrial OS=Homo sapiens OX=9606 GN=HSPD1 PE=1 SV=2" 10 2257.4 - 560101 - - - -0.629 - 2.063 0.374 - 282.5 1 1 0 -0.0007 10 0 0 0 5.88E+06 4.71E+06 - - - 3.8245 0.9549 221125_WJC_METTL3_EV_vs_WT_F04.10883.10883.2 0.0665 18-Nov L.K[136.11]VGLQVVAVK[136.11].A "sp|P10809|CH60_HUMAN,tr|A0A7I2V2X6|A0A7I2V2X6_HUMAN,tr|A0A7I2YQK6|A0A7I2YQK6_HUMAN,tr|A0A7I2V599|A0A7I2V599_HUMAN,tr|A0A7I2V5M1|A0A7I2V5M1_HUMAN" 5 1055.7038 1.25 45373 10883 2 1055.702503 528.8592 "60 kDa heat shock protein, mitochondrial OS=Homo sapiens OX=9606 GN=HSPD1 PE=1 SV=2" 10 2257.6 - 495266 - - - -1.1964 - 1.436 0.378 - 255.6 1 1 0 -0.0013 10 0 0 0 5.88E+06 4.71E+06 - - - 2.8426 0.9953 221125_WJC_METTL3_EV_vs_WT_F04.10885.10885.3 0.0535 Nov-44 K.VAEDFVSPEHVK[136.11].H "sp|Q9Y4C1|KDM3A_HUMAN,sp|Q7LBC6|KDM3B_HUMAN" 2 1363.6863 1.03 45375 10885 3 1363.682453 455.5694 Lysine-specific demethylase 3A OS=Homo sapiens OX=9606 GN=KDM3A PE=1 SV=4 4.65 2257.9 - 431741 - - - -2.8438 - 1.85 0.253 - 124.3 1 2 0 -0.0039 12 0 0 0 1.17E+07 1.14E+07 - - - 3.0648 1 221125_WJC_METTL3_EV_vs_WT_F04.10890.10890.3 2.05E-06 15/44 R.TNAENEFVTIKK.D sp|P04264|K2C1_HUMAN 1 1392.7249 238.46 45379 10890 3 1392.725508 465.2489 "Keratin, type II cytoskeletal 1 OS=Homo sapiens OX=9606 GN=KRT1 PE=1 SV=6" 5.81 2258.5 - 1.48E+06 - - - 0.4401 - 2.87 0.552 - 282.6 1 2 0 0.0006 12 0 0 0 1.34E+07 5.63E+04 - - - 7.6165 0.9997 221125_WJC_METTL3_EV_vs_WT_F04.10891.10891.2 0.0019 18-Aug R.VLTVINQTQK.E "sp|P42766|RL35_HUMAN,tr|F2Z388|F2Z388_HUMAN" 2 1142.6659 0.59 45380 10891 2 1142.665839 572.3402 60S ribosomal protein L35 OS=Homo sapiens OX=9606 GN=RPL35 PE=1 SV=2 8.72 2258.5 - 3.31E+06 - - - -0.0735 - 1.823 0.37 - 167.8 1 2 0 -0.0001 10 0 0 0 4.59E+07 7.77E+07 - - - 3.4499 1 221125_WJC_METTL3_EV_vs_WT_F04.10892.10892.3 3.15E-05 Nov-36 R.TFGMAEEYHR.E "sp|Q8N1F7|NUP93_HUMAN,tr|H3BM93|H3BM93_HUMAN,tr|H3BV11|H3BV11_HUMAN,tr|H3BRI8|H3BRI8_HUMAN,tr|H3BNN5|H3BNN5_HUMAN,tr|H3BVG0|H3BVG0_HUMAN" 6 1239.5343 1.98 45381 10892 3 1239.533271 414.1854 Nuclear pore complex protein Nup93 OS=Homo sapiens OX=9606 GN=NUP93 PE=1 SV=2 5.37 2258.6 - 1.99E+06 - - - -0.7955 - 2.187 0.522 - 180.3 1 2 0 -0.001 10 0 0 0 3.57E+07 1.80E+07 - - - 6.6448 1 221125_WJC_METTL3_EV_vs_WT_F04.10893.10893.3 0.000172 14/36 R.TFGMAEEYHR[166.11].E "sp|Q8N1F7|NUP93_HUMAN,tr|H3BM93|H3BM93_HUMAN,tr|H3BV11|H3BV11_HUMAN,tr|H3BRI8|H3BRI8_HUMAN,tr|H3BNN5|H3BNN5_HUMAN,tr|H3BVG0|H3BVG0_HUMAN" 6 1249.5425 1.98 45382 10893 3 1249.541384 417.5215 Nuclear pore complex protein Nup93 OS=Homo sapiens OX=9606 GN=NUP93 PE=1 SV=2 5.37 2258.7 - 1.11E+06 - - - -0.9147 - 2.329 0.462 - 299.8 1 2 0 -0.0011 10 0 0 0 3.57E+07 1.80E+07 - - - 6.1596 0.9999 221125_WJC_METTL3_EV_vs_WT_F04.10895.10895.3 0.00118 13/36 K.VTLLEGDHVR[166.11].F "sp|O75534|CSDE1_HUMAN,tr|E9PLT0|E9PLT0_HUMAN" 2 1147.6225 0.69 45384 10895 3 1147.620887 383.5481 Cold shock domain-containing protein E1 OS=Homo sapiens OX=9606 GN=CSDE1 PE=1 SV=2 5.32 2258.9 - 758634 - - - -1.3985 - 2.152 0.415 - 248.1 1 2 0 -0.0016 10 0 0 0 1.71E+07 2.47E+07 - - - 5.4046 0.9187 221125_WJC_METTL3_EV_vs_WT_F04.10897.10897.2 0.119 20-Sep K.DAISGIGTDEK[136.11].C "sp|P08133|ANXA6_HUMAN,tr|E5RK63|E5RK63_HUMAN,tr|E5RI05|E5RI05_HUMAN,tr|E5RJF5|E5RJF5_HUMAN" 4 1112.5441 3.63 45386 10897 2 1112.548775 557.2793 Annexin A6 OS=Homo sapiens OX=9606 GN=ANXA6 PE=1 SV=3 4.03 2259.1 - 545216 - - - 4.2174 - 1.267 0.15 - 150.6 1 2 0 0.0047 11 0 0 0 2.37E+07 6.54E+06 - - - 0.7876 0.9952 221125_WJC_METTL3_EV_vs_WT_F04.10898.10898.3 0.00205 Nov-36 K.YIEDK[136.11]DVFQK[136.11].F "sp|Q13616|CUL1_HUMAN,tr|A0A0C4DGX4|A0A0C4DGX4_HUMAN,tr|A0A590UJ21|A0A590UJ21_HUMAN,tr|A0A590UJ50|A0A590UJ50_HUMAN,tr|A0A590UJ56|A0A590UJ56_HUMAN,tr|A0A590UJC4|A0A590UJC4_HUMAN,tr|A0A590UK34|A0A590UK34_HUMAN" 7 1299.6682 0.06 45387 10898 3 1299.666864 434.23 Cullin-1 OS=Homo sapiens OX=9606 GN=CUL1 PE=1 SV=2 4.56 2259.3 - 538752 - - - -1.0033 - 1.52 0.315 - 62.6 1 2 1 -0.0013 10 0 0 0 1.29E+06 2.35E+07 - - - 3.2744 0.9936 221125_WJC_METTL3_EV_vs_WT_F04.10900.10900.3 0.0101 Dec-36 K.VTLLEGDHVR.F "sp|O75534|CSDE1_HUMAN,tr|E9PLT0|E9PLT0_HUMAN" 2 1137.6142 0.4 45389 10900 3 1137.614971 380.212 Cold shock domain-containing protein E1 OS=Homo sapiens OX=9606 GN=CSDE1 PE=1 SV=2 5.32 2259.5 - 387760 - - - 0.6584 - 1.461 0.218 - 178.9 1 2 0 0.0007 10 0 0 0 9.57E+06 2.38E+07 - - - 2.0775 0.9998 221125_WJC_METTL3_EV_vs_WT_F04.10906.10906.2 0.000169 18-Sep R.FQTEIQTVNK[136.11].Q "sp|P14868|SYDC_HUMAN,tr|H7BZ35|H7BZ35_HUMAN" 2 1214.6387 1.74 45393 10906 2 1214.639617 608.3266 "Aspartate--tRNA ligase, cytoplasmic OS=Homo sapiens OX=9606 GN=DARS1 PE=1 SV=2" 6 2260.1 - 1.83E+06 - - - 0.7945 - 1.88 0.514 - 198.8 1 2 0 0.001 10 0 0 0 4.02E+07 2.30E+07 - - - 4.5992 1 221125_WJC_METTL3_EV_vs_WT_F04.10908.10908.2 8.87E-05 13/28 R.SLAEAC[160.03]SEGDVNAVR.K "sp|O75179|ANR17_HUMAN,tr|H0YM23|H0YM23_HUMAN,tr|A0A1W2PQ15|A0A1W2PQ15_HUMAN" 3 1576.7151 3.97 45395 10908 2 1576.715503 789.3648 Ankyrin repeat domain-containing protein 17 OS=Homo sapiens OX=9606 GN=ANKRD17 PE=1 SV=3 4.14 2260.4 - 351725 - - - 0.2334 - 3.045 0.642 - 568.9 1 2 0 0.0004 15 0 0 0 3.28E+06 8.28E+05 - - - 6.5203 0.9995 221125_WJC_METTL3_EV_vs_WT_F04.10915.10915.2 0.000234 22-Sep R.LAIQGPEDSPSR.Q sp|Q15773|MLF2_HUMAN 1 1268.6361 1.46 45400 10915 2 1268.633225 635.3253 Myeloid leukemia factor 2 OS=Homo sapiens OX=9606 GN=MLF2 PE=1 SV=1 4.37 2261.2 - 592630 - - - -2.2504 - 2.058 0.437 - 240.8 1 2 0 -0.0029 12 0 0 0 3.32E+07 2.28E+07 - - - 4.1668 0.9976 221125_WJC_METTL3_EV_vs_WT_F04.10916.10916.2 0.0322 16-Jul K.NEFQGELEK[136.11].Q "sp|Q8NBJ4|GOLM1_HUMAN,tr|F8WAT9|F8WAT9_HUMAN,tr|C9J941|C9J941_HUMAN,tr|C9JYM4|C9JYM4_HUMAN" 4 1100.523 2.9 45401 10916 2 1100.52351 551.2688 Golgi membrane protein 1 OS=Homo sapiens OX=9606 GN=GOLM1 PE=1 SV=1 4.25 2261.4 - 351194 - - - 0.5052 - 1.292 0.262 - 137.3 1 2 0 0.0006 9 0 0 0 1.42E+07 4.91E+06 - - - 1.7171 0.984 221125_WJC_METTL3_EV_vs_WT_F04.10921.10921.3 0.339 Sep-36 R.FGDDYRPGLR.R sp|Q7LGA3|HS2ST_HUMAN 1 1194.5782 1.16 45404 10921 3 1194.577097 399.2 Heparan sulfate 2-O-sulfotransferase 1 OS=Homo sapiens OX=9606 GN=HS2ST1 PE=1 SV=1 5.96 2262 - 2.36E+06 - - - -0.8991 - 1.436 0.173 - 81.7 1 2 0 -0.0011 10 0 0 0 6.54E+07 5.62E+07 - - - 1.5253 0.9999 221125_WJC_METTL3_EV_vs_WT_F04.10923.10923.2 2.01E-06 13/20 K.VTADVINAAEK.L "sp|O43175|SERA_HUMAN,tr|A0A2C9F2M7|A0A2C9F2M7_HUMAN,tr|A0A286YFB2|A0A286YFB2_HUMAN,tr|A0A286YF34|A0A286YF34_HUMAN,tr|A0A286YFC8|A0A286YFC8_HUMAN,tr|A0A286YF22|A0A286YF22_HUMAN,tr|A0A286YFL2|A0A286YFL2_HUMAN,tr|A0A286YFA2|A0A286YFA2_HUMAN,tr|A0A286YFM8|A0A286YFM8_HUMAN,tr|A0A286YER3|A0A286YER3_HUMAN" 10 1129.5979 1.27 45406 10923 2 1129.598468 565.8062 D-3-phosphoglycerate dehydrogenase OS=Homo sapiens OX=9606 GN=PHGDH PE=1 SV=4 4.37 2262.1 - 1.77E+06 - - - 0.5002 - 2.594 0.504 - 724.7 1 2 0 0.0006 11 0 0 0 1.88E+08 1.48E+08 - - - 5.342 0.9976 221125_WJC_METTL3_EV_vs_WT_F04.10925.10925.2 1.26 18-Aug R.IHDPQLLTER.A "sp|P14868|SYDC_HUMAN,tr|H7BZ35|H7BZ35_HUMAN" 2 1220.6513 0.4 45408 10925 2 1220.650265 611.3329 "Aspartate--tRNA ligase, cytoplasmic OS=Homo sapiens OX=9606 GN=DARS1 PE=1 SV=2" 5.32 2262.4 - 350570 - - - -0.8774 - 1.484 0.216 - 215 1 2 0 -0.0011 10 0 0 0 5.54E+06 1.39E+07 - - - 1.7379 0.9782 221125_WJC_METTL3_EV_vs_WT_F04.10927.10927.2 2.96 14-May K.QPTIFQNK[136.11].K "sp|P62280|RS11_HUMAN,tr|M0QZC5|M0QZC5_HUMAN,tr|M0R1H6|M0R1H6_HUMAN" 3 982.5327 1.01 45409 10927 2 982.532488 492.2736 40S ribosomal protein S11 OS=Homo sapiens OX=9606 GN=RPS11 PE=1 SV=3 8.75 2262.6 - 5.59E+07 - - - -0.2473 - 1.174 0.078 - 136.3 1 2 0 -0.0002 8 0 0 0 1.43E+09 1.41E+09 - - - 0.1008 0.9999 221125_WJC_METTL3_EV_vs_WT_F04.10929.10929.2 3.79E-06 20-Dec K.VTADVINAAEK[136.11].L "sp|O43175|SERA_HUMAN,tr|A0A2C9F2M7|A0A2C9F2M7_HUMAN,tr|A0A286YFB2|A0A286YFB2_HUMAN,tr|A0A286YF34|A0A286YF34_HUMAN,tr|A0A286YFC8|A0A286YFC8_HUMAN,tr|A0A286YF22|A0A286YF22_HUMAN,tr|A0A286YFL2|A0A286YFL2_HUMAN,tr|A0A286YFA2|A0A286YFA2_HUMAN,tr|A0A286YFM8|A0A286YFM8_HUMAN,tr|A0A286YER3|A0A286YER3_HUMAN" 10 1137.6121 1.27 45410 10929 2 1137.612476 569.8133 D-3-phosphoglycerate dehydrogenase OS=Homo sapiens OX=9606 GN=PHGDH PE=1 SV=4 4.37 2262.8 - 2.44E+06 - - - 0.3279 - 2.476 0.516 - 535.1 1 2 0 0.0004 11 0 0 0 1.88E+08 1.48E+08 - - - 5.3047 0.9997 221125_WJC_METTL3_EV_vs_WT_F04.10933.10933.2 4.13E-06 26-May R.AGPGSEELTVTNAR[166.11].Y sp|Q9BW19|KIFC1_HUMAN 1 1410.6978 1.98 45414 10933 2 1410.695115 706.3562 Kinesin-like protein KIFC1 OS=Homo sapiens OX=9606 GN=KIFC1 PE=1 SV=2 4.53 2263.3 - 134877 - - - -1.9331 - 1.586 0.573 - 66.5 1 2 0 -0.0027 14 0 0 0 8.96E+05 4.53E+05 - - - 4.4297 0.998 221125_WJC_METTL3_EV_vs_WT_F04.10935.10935.2 1.46 18-Sep K.SASVAPFTC[160.03]K[136.11].T sp|P49790|NU153_HUMAN 1 1074.5259 1.54 45415 10935 2 1074.525289 538.2702 Nuclear pore complex protein Nup153 OS=Homo sapiens OX=9606 GN=NUP153 PE=1 SV=2 7.94 2263.5 - 1.03E+06 - - - -0.5975 - 1.609 0.197 - 410 1 2 0 -0.0006 10 0 0 0 5.25E+07 3.41E+07 - - - 1.8234 0.9998 221125_WJC_METTL3_EV_vs_WT_F04.10937.10937.2 0.00334 18-Aug K.NFGEDMDDER.L "sp|Q9H361|PABP3_HUMAN,sp|P11940|PABP1_HUMAN,tr|A0A7I2YQE4|A0A7I2YQE4_HUMAN,tr|A0A7I2V649|A0A7I2V649_HUMAN,tr|H0YAR2|H0YAR2_HUMAN,tr|E7ERJ7|E7ERJ7_HUMAN,tr|A0A7I2YQ88|A0A7I2YQ88_HUMAN,tr|H0YBN4|H0YBN4_HUMAN,tr|A0A087WTT1|A0A087WTT1_HUMAN,tr|A0A7I2YQ90|A0A7I2YQ90_HUMAN,tr|A0A7I2V4N4|A0A7I2V4N4_HUMAN,tr|E7EQV3|E7EQV3_HUMAN" 12 1226.451 1.48 45416 10937 2 1226.451476 614.2328 Polyadenylate-binding protein 3 OS=Homo sapiens OX=9606 GN=PABPC3 PE=1 SV=2 3.77 2263.7 - 2.04E+06 - - - 0.4036 - 1.777 0.473 - 257.5 1 2 0 0.0005 10 0 0 0 1.26E+08 8.51E+07 - - - 4.1392 0.9998 221125_WJC_METTL3_EV_vs_WT_F04.10938.10938.2 0.000255 18-Oct K.NFGEDMDDER[166.11].L "sp|Q9H361|PABP3_HUMAN,sp|P11940|PABP1_HUMAN,tr|A0A7I2YQE4|A0A7I2YQE4_HUMAN,tr|A0A7I2V649|A0A7I2V649_HUMAN,tr|H0YAR2|H0YAR2_HUMAN,tr|E7ERJ7|E7ERJ7_HUMAN,tr|A0A7I2YQ88|A0A7I2YQ88_HUMAN,tr|H0YBN4|H0YBN4_HUMAN,tr|A0A087WTT1|A0A087WTT1_HUMAN,tr|A0A7I2YQ90|A0A7I2YQ90_HUMAN,tr|A0A7I2V4N4|A0A7I2V4N4_HUMAN,tr|E7EQV3|E7EQV3_HUMAN" 12 1236.4593 1.48 45417 10938 2 1236.459613 619.2369 Polyadenylate-binding protein 3 OS=Homo sapiens OX=9606 GN=PABPC3 PE=1 SV=2 3.77 2263.8 - 1.60E+06 - - - 0.2928 - 1.849 0.457 - 406.2 1 2 0 0.0004 10 0 0 0 1.26E+08 8.51E+07 - - - 4.1319 0.9998 221125_WJC_METTL3_EV_vs_WT_F04.10945.10945.3 0.000676 Jul-40 K.VISSVSYYTHR[166.11].H "sp|O00507|USP9Y_HUMAN,sp|Q93008|USP9X_HUMAN" 2 1320.6702 0.94 45422 10945 3 1320.669346 441.2307 Probable ubiquitin carboxyl-terminal hydrolase FAF-Y OS=Homo sapiens OX=9606 GN=USP9Y PE=2 SV=2 8.57 2264.7 - 173217 - - - -0.6239 - 1.634 0.411 - 88 1 2 0 -0.0008 11 0 0 0 5.55E+06 5.90E+06 - - - 4.5169 0.9949 221125_WJC_METTL3_EV_vs_WT_F04.10947.10947.2 0.131 16-Jul K.EDLC[160.03]ISPGK.L sp|Q96B26|EXOS8_HUMAN 1 1017.4801 0.86 45424 10947 2 1017.48076 509.7473 Exosome complex component RRP43 OS=Homo sapiens OX=9606 GN=EXOSC8 PE=1 SV=1 4.37 2264.9 - 303209 - - - 0.6516 - 1.066 0.266 - 147.3 1 2 0 0.0007 9 0 0 0 5.83E+06 6.75E+06 - - - 1.1904 0.9997 221125_WJC_METTL3_EV_vs_WT_F04.10948.10948.2 3.43E-05 16-Jun K.GNNVYC[160.03]LDR.E "sp|P53621|COPA_HUMAN,tr|A0A3B3ISC6|A0A3B3ISC6_HUMAN,tr|A0A3B3IS84|A0A3B3IS84_HUMAN,tr|A0A3B3IU89|A0A3B3IU89_HUMAN,tr|A0A3B3IT15|A0A3B3IT15_HUMAN" 5 1109.4924 0.14 45425 10948 2 1109.492266 555.7535 Coatomer subunit alpha OS=Homo sapiens OX=9606 GN=COPA PE=1 SV=2 5.83 2265 - 269414 - - - -0.1145 - 1.625 0.418 - 164.9 1 2 0 -0.0001 9 0 0 0 3.18E+06 2.33E+07 - - - 3.5329 0.9982 221125_WJC_METTL3_EV_vs_WT_F04.10949.10949.2 0.0144 16-Oct K.TAVC[160.03]DIPPR.G "sp|P04350|TBB4A_HUMAN,sp|Q9BVA1|TBB2B_HUMAN,sp|A6NNZ2|TBB8B_HUMAN,sp|P07437|TBB5_HUMAN,sp|Q13885|TBB2A_HUMAN,sp|P68371|TBB4B_HUMAN,sp|Q3ZCM7|TBB8_HUMAN,tr|Q5ST81|Q5ST81_HUMAN,tr|Q5JP53|Q5JP53_HUMAN,tr|A0A075B736|A0A075B736_HUMAN,tr|Q5SQY0|Q5SQY0_HUMAN" 11 1027.5121 0.71 45426 10949 2 1027.509249 514.7633 Tubulin beta-4A chain OS=Homo sapiens OX=9606 GN=TUBB4A PE=1 SV=2 5.5 2265.2 - 243039 - - - -2.7406 - 1.823 0.304 - 340.8 1 2 0 -0.0028 9 0 0 0 2.87E+06 4.02E+06 - - - 3.0227 0.9993 221125_WJC_METTL3_EV_vs_WT_F04.10951.10951.2 0.0034 24-Jul K.LNQPPEDGISSVK[136.11].F "sp|O43684|BUB3_HUMAN,tr|J3QT28|J3QT28_HUMAN,tr|J3QSX4|J3QSX4_HUMAN" 3 1390.7184 0.52 45427 10951 2 1390.718833 696.3665 Mitotic checkpoint protein BUB3 OS=Homo sapiens OX=9606 GN=BUB3 PE=1 SV=1 4.37 2265.5 - 239589 - - - 0.3408 - 1.505 0.363 - 117.3 1 2 0 0.0005 13 0 0 0 4.62E+06 8.93E+06 - - - 2.7711 0.9984 221125_WJC_METTL3_EV_vs_WT_F04.10955.10955.2 3.61E-05 18-Oct R.LKYENEVALR.Q "sp|P13645|K1C10_HUMAN,tr|A0A1B0GVI3|A0A1B0GVI3_HUMAN" 2 1233.6717 158.82 45430 10955 2 1233.672118 617.8431 "Keratin, type I cytoskeletal 10 OS=Homo sapiens OX=9606 GN=KRT10 PE=1 SV=6" 6.14 2265.8 - 3.79E+06 - - - 0.3088 - 2.142 0.466 - 244 1 2 1 0.0004 10 0 0 0 1.49E+09 9.37E+06 - - - 4.609 0.7625 221125_WJC_METTL3_EV_vs_WT_F04.10956.10956.2 0.0691 20-Jun R.KSEPPSALVGA.G sp|Q9H7S9|ZN703_HUMAN 1 1054.5659 1.1 45431 10956 2 1054.563773 528.2902 Zinc finger protein 703 OS=Homo sapiens OX=9606 GN=ZNF703 PE=1 SV=1 6 2266 - 245550 - - - -1.9932 - 1.441 0.219 - 97.7 1 1 0 -0.0021 11 0 0 0 6.68E+06 6.06E+06 - - - 1.6462 0.9986 221125_WJC_METTL3_EV_vs_WT_F04.10961.10961.3 0.0105 Sep-36 R.FGDDYR[166.11]PGLR[166.11].R sp|Q7LGA3|HS2ST_HUMAN 1 1214.5947 1.16 45434 10961 3 1214.593042 405.8722 Heparan sulfate 2-O-sulfotransferase 1 OS=Homo sapiens OX=9606 GN=HS2ST1 PE=1 SV=1 5.96 2266.5 - 4.03E+06 - - - -1.3741 - 1.529 0.306 - 82.2 1 2 0 -0.0017 10 0 0 0 6.54E+07 5.62E+07 - - - 3.1912 0.9991 221125_WJC_METTL3_EV_vs_WT_F04.10962.10962.2 0.00297 16-Jun K.DAYSSFGSR[166.11].S "sp|O00571|DDX3X_HUMAN,sp|O15523|DDX3Y_HUMAN,tr|A0A2R8YFR4|A0A2R8YFR4_HUMAN,tr|A0A2R8YCW1|A0A2R8YCW1_HUMAN,tr|A0A2R8YDH3|A0A2R8YDH3_HUMAN,tr|A0A2R8Y645|A0A2R8Y645_HUMAN,tr|A0A2R8YF78|A0A2R8YF78_HUMAN,tr|C9J8G5|C9J8G5_HUMAN,tr|A0A2R8YCU0|A0A2R8YCU0_HUMAN,tr|A0A0D9SFB3|A0A0D9SFB3_HUMAN,tr|A0A2R8YFS5|A0A2R8YFS5_HUMAN,tr|A0A0D9SF53|A0A0D9SF53_HUMAN,tr|A0A2R8Y650|A0A2R8Y650_HUMAN,tr|A0A087WX09|A0A087WX09_HUMAN,tr|C9J081|C9J081_HUMAN,tr|A0A2R8Y5G6|A0A2R8Y5G6_HUMAN,tr|A0A0D9SG12|A0A0D9SG12_HUMAN,tr|F6S8Q4|F6S8Q4_HUMAN,tr|A0A2U3TZJ9|A0A2U3TZJ9_HUMAN,tr|A0A2R8Y4A4|A0A2R8Y4A4_HUMAN,tr|A0A2R8YF89|A0A2R8YF89_HUMAN" 21 998.4333 1.22 45435 10962 2 998.432443 500.2239 ATP-dependent RNA helicase DDX3X OS=Homo sapiens OX=9606 GN=DDX3X PE=1 SV=3 5.84 2266.6 - 1.18E+06 - - - -0.8523 - 1.624 0.292 - 96.4 1 2 0 -0.0009 9 0 0 0 2.19E+07 1.80E+07 - - - 2.6003 0.9999 221125_WJC_METTL3_EV_vs_WT_F04.10963.10963.2 0.000602 20-Dec K.IC[160.03]EPGYSPTYK.Q "sp|P07858|CATB_HUMAN,tr|A0A7I2V440|A0A7I2V440_HUMAN,tr|E9PQM1|E9PQM1_HUMAN,tr|A0A7I2V668|A0A7I2V668_HUMAN,tr|A0A7P0NGZ6|A0A7P0NGZ6_HUMAN,tr|A0A7I2YQK9|A0A7I2YQK9_HUMAN,tr|E9PHZ5|E9PHZ5_HUMAN,tr|E9PR21|E9PR21_HUMAN" 8 1313.5962 3.53 45436 10963 2 1313.595826 657.8054 Cathepsin B OS=Homo sapiens OX=9606 GN=CTSB PE=1 SV=3 5.99 2266.8 - 1.01E+06 - - - -0.2763 - 2.181 0.477 - 554.5 1 2 0 -0.0004 11 0 0 0 3.74E+07 1.06E+07 - - - 4.6735 0.9874 221125_WJC_METTL3_EV_vs_WT_F04.10966.10966.2 0.0558 18-Jul K.DYTVTQVPPK[136.11].H "sp|Q8N5Z5|KCD17_HUMAN,tr|A0A087WX35|A0A087WX35_HUMAN,tr|H0Y731|H0Y731_HUMAN" 3 1154.6063 1.91 45439 10966 2 1154.609854 578.3104 BTB\POZ domain-containing protein KCTD17 OS=Homo sapiens OX=9606 GN=KCTD17 PE=1 SV=3 5.83 2267.1 - 419496 - - - 3.0868 - 1.435 0.208 - 166.2 1 2 0 0.0036 10 0 0 0 4.28E+07 2.24E+07 - - - 1.5843 0.9993 221125_WJC_METTL3_EV_vs_WT_F04.10967.10967.2 0.00528 26-Sep R.LAASASTQQLQEVK[136.11].A sp|O95235|KI20A_HUMAN 1 1480.7977 0.68 45440 10967 2 1480.798113 741.4061 Kinesin-like protein KIF20A OS=Homo sapiens OX=9606 GN=KIF20A PE=1 SV=1 6 2267.3 - 127307 - - - 0.2978 - 1.648 0.333 - 186.6 1 2 0 0.0004 14 0 0 0 1.35E+06 1.99E+06 - - - 2.754 0.9997 221125_WJC_METTL3_EV_vs_WT_F04.10968.10968.2 0.000266 Jul-32 R.GSGGLGGAC[160.03]GGAGFGSR.S "sp|P48668|K2C6C_HUMAN,sp|P04259|K2C6B_HUMAN,sp|P02538|K2C6A_HUMAN" 3 1423.6263 999 45441 10968 2 1423.623573 712.8204 "Keratin, type II cytoskeletal 6C OS=Homo sapiens OX=9606 GN=KRT6C PE=1 SV=3" 8.25 2267.4 - 121694 - - - -1.8874 - 1.633 0.581 - 65.9 1 2 0 -0.0027 17 0 0 0 1.73E+06 0.00E+00 - - - 4.5371 0.9987 221125_WJC_METTL3_EV_vs_WT_F04.10970.10970.2 0.0855 20-Oct K.TEVPGSVTEYK[136.11].V "sp|P34949|MPI_HUMAN,tr|H3BPB8|H3BPB8_HUMAN,tr|F5GX71|F5GX71_HUMAN" 3 1216.6067 1.3 45442 10970 2 1216.607242 609.3106 Mannose-6-phosphate isomerase OS=Homo sapiens OX=9606 GN=MPI PE=1 SV=2 4.53 2267.6 - 525658 - - - 0.4587 - 1.614 0.253 - 254.9 1 2 0 0.0006 11 0 0 0 2.13E+07 1.65E+07 - - - 2.2045 0.9808 221125_WJC_METTL3_EV_vs_WT_F04.10972.10972.3 0.0547 Oct-36 K.AVLDLESERR.W "sp|Q14527|HLTF_HUMAN,tr|H7C5K0|H7C5K0_HUMAN,tr|A0A0C4DGA6|A0A0C4DGA6_HUMAN" 3 1186.6306 1.62 45443 10972 3 1186.630609 396.5508 Helicase-like transcription factor OS=Homo sapiens OX=9606 GN=HLTF PE=1 SV=2 4.68 2267.8 - 2.98E+06 - - - 0.0076 - 1.694 0.12 - 146.7 1 2 0 0 10 0 0 0 5.38E+07 3.33E+07 - - - 1.4172 0.9929 221125_WJC_METTL3_EV_vs_WT_F04.10974.10974.2 2.40E-05 16-Dec L.KYENEVALR.Q "sp|P13645|K1C10_HUMAN,tr|A0A1B0GVI3|A0A1B0GVI3_HUMAN" 2 1120.5877 1.66 45445 10974 2 1120.588624 561.3011 "Keratin, type I cytoskeletal 10 OS=Homo sapiens OX=9606 GN=KRT10 PE=1 SV=6" 6.14 2267.9 - 2.19E+06 - - - 0.8487 - 2.244 0.53 - 570.4 1 1 0 0.001 9 0 0 0 1.55E+08 9.32E+07 - - - 5.2936 0.9993 221125_WJC_METTL3_EV_vs_WT_F04.10975.10975.2 0.108 20-Oct R.LSDYSIGPNSK[136.11].L "sp|P11441|UBL4A_HUMAN,tr|Q5HY81|Q5HY81_HUMAN" 2 1187.5914 0.91 45446 10975 2 1187.5881 594.803 Ubiquitin-like protein 4A OS=Homo sapiens OX=9606 GN=UBL4A PE=1 SV=1 5.83 2268 - 1.66E+06 - - - -2.7518 - 2.239 0.392 - 260.9 1 2 0 -0.0033 11 0 0 0 4.71E+07 5.19E+07 - - - 4.1158 0.9996 221125_WJC_METTL3_EV_vs_WT_F04.10976.10976.2 0.00124 16-Jul K.DAYSSFGSR.S "sp|O00571|DDX3X_HUMAN,sp|O15523|DDX3Y_HUMAN,tr|A0A2R8YFR4|A0A2R8YFR4_HUMAN,tr|A0A2R8YCW1|A0A2R8YCW1_HUMAN,tr|A0A2R8YDH3|A0A2R8YDH3_HUMAN,tr|A0A2R8Y645|A0A2R8Y645_HUMAN,tr|A0A2R8YF78|A0A2R8YF78_HUMAN,tr|C9J8G5|C9J8G5_HUMAN,tr|A0A2R8YCU0|A0A2R8YCU0_HUMAN,tr|A0A0D9SFB3|A0A0D9SFB3_HUMAN,tr|A0A2R8YFS5|A0A2R8YFS5_HUMAN,tr|A0A0D9SF53|A0A0D9SF53_HUMAN,tr|A0A2R8Y650|A0A2R8Y650_HUMAN,tr|A0A087WX09|A0A087WX09_HUMAN,tr|C9J081|C9J081_HUMAN,tr|A0A2R8Y5G6|A0A2R8Y5G6_HUMAN,tr|A0A0D9SG12|A0A0D9SG12_HUMAN,tr|F6S8Q4|F6S8Q4_HUMAN,tr|A0A2U3TZJ9|A0A2U3TZJ9_HUMAN,tr|A0A2R8Y4A4|A0A2R8Y4A4_HUMAN,tr|A0A2R8YF89|A0A2R8YF89_HUMAN" 21 988.425 1.22 45447 10976 2 988.423987 495.2198 ATP-dependent RNA helicase DDX3X OS=Homo sapiens OX=9606 GN=DDX3X PE=1 SV=3 5.84 2268.1 - 1.65E+06 - - - -1.0491 - 1.469 0.451 - 135.9 1 2 0 -0.001 9 0 0 0 2.19E+07 1.80E+07 - - - 3.4844 0.9998 221125_WJC_METTL3_EV_vs_WT_F04.10978.10978.2 0.000668 18-Sep R.AATEELLANK.L "sp|P82094|TMF1_HUMAN,tr|A0A2R8Y7M0|A0A2R8Y7M0_HUMAN" 2 1058.5608 0.73 45449 10978 2 1058.560419 530.2877 TATA element modulatory factor OS=Homo sapiens OX=9606 GN=TMF1 PE=1 SV=2 4.53 2268.3 - 580845 - - - -0.3495 - 2.202 0.434 - 315.3 1 2 0 -0.0004 10 0 0 0 2.61E+07 3.55E+07 - - - 4.4498 0.9993 221125_WJC_METTL3_EV_vs_WT_F04.10979.10979.2 2.09E-05 20-Nov R.LDQC[160.03]PESPLQR.C sp|Q5T749|KPRP_HUMAN 1 1341.6347 2.27 45450 10979 2 1341.637436 671.8246 Keratinocyte proline-rich protein OS=Homo sapiens OX=9606 GN=KPRP PE=1 SV=1 4.37 2268.4 - 553322 - - - 2.0393 - 2.107 0.355 - 382.8 1 2 0 0.0027 11 0 0 0 2.08E+07 9.15E+06 - - - 3.6783 0.9999 221125_WJC_METTL3_EV_vs_WT_F04.10982.10982.2 3.42E-05 22-Oct K.SVQTTLQTDEVK.N "sp|O94905|ERLN2_HUMAN,sp|O75477|ERLN1_HUMAN,tr|E5RHW4|E5RHW4_HUMAN,tr|B0QZ43|B0QZ43_HUMAN" 4 1347.6882 1.42 45453 10982 2 1347.688007 674.8514 Erlin-2 OS=Homo sapiens OX=9606 GN=ERLIN2 PE=1 SV=1 4.37 2268.8 - 364263 - - - -0.1247 - 2.215 0.462 - 260.5 1 2 0 -0.0002 12 0 0 0 2.59E+07 1.83E+07 - - - 4.5457 0.9706 221125_WJC_METTL3_EV_vs_WT_F04.10987.10987.3 0.00196 Dec-36 R.ALVVEMSRPR.P "sp|Q96PK6|RBM14_HUMAN,tr|B8ZZ74|B8ZZ74_HUMAN,tr|F8WDX3|F8WDX3_HUMAN,tr|A0A0A0MSL8|A0A0A0MSL8_HUMAN,tr|A0A0A6YYI9|A0A0A6YYI9_HUMAN" 5 1156.6387 1.61 45456 10987 3 1156.635878 386.5535 RNA-binding protein 14 OS=Homo sapiens OX=9606 GN=RBM14 PE=1 SV=2 9.64 2269.3 - 934776 - - - -2.4078 - 2.238 0.371 - 216.3 1 1 0 -0.0028 10 0 0 0 6.23E+07 3.87E+07 - - - 5.0282 1 221125_WJC_METTL3_EV_vs_WT_F04.10992.10992.2 3.45E-09 15/26 R.SPEVLSGGEDGAVR[166.11].L sp|Q86W42|THOC6_HUMAN 1 1381.6713 0.82 45461 10992 2 1381.667991 691.8429 THO complex subunit 6 homolog OS=Homo sapiens OX=9606 GN=THOC6 PE=1 SV=1 4.14 2269.8 - 343574 - - - -2.3899 - 3.048 0.564 - 824.7 1 2 0 -0.0033 14 0 0 0 7.27E+06 8.87E+06 - - - 6.0024 0.9801 221125_WJC_METTL3_EV_vs_WT_F04.10999.10999.3 0.0388 Dec-44 K.YIQQTKPLTLER.T sp|O43809|CPSF5_HUMAN 1 1488.83 0.88 45466 10999 3 1488.825483 497.284 Cleavage and polyadenylation specificity factor subunit 5 OS=Homo sapiens OX=9606 GN=NUDT21 PE=1 SV=1 8.59 2270.7 - 2.07E+06 - - - -3.0534 - 1.343 0.256 - 88.2 1 2 0 -0.0045 12 0 0 0 2.90E+07 3.31E+07 - - - 2.2103 0.9991 221125_WJC_METTL3_EV_vs_WT_F04.11001.11001.2 0.0258 18-Aug K.DYTVTQVPPK.H "sp|Q8N5Z5|KCD17_HUMAN,tr|A0A087WX35|A0A087WX35_HUMAN,tr|H0Y731|H0Y731_HUMAN" 3 1146.5921 1.07 45468 11001 2 1146.591437 574.3033 BTB\POZ domain-containing protein KCTD17 OS=Homo sapiens OX=9606 GN=KCTD17 PE=1 SV=3 5.83 2270.9 - 1.18E+06 - - - -0.5695 - 1.61 0.284 - 208.3 1 2 0 -0.0007 10 0 0 0 1.21E+07 1.14E+07 - - - 2.4677 0.891 221125_WJC_METTL3_EV_vs_WT_F04.11002.11002.2 2.23 12-Aug R.R[166.11]LDVFEK[136.11].T "sp|Q99460|PSMD1_HUMAN,tr|A0A7I2V4X0|A0A7I2V4X0_HUMAN,tr|A0A7I2V2K8|A0A7I2V2K8_HUMAN,tr|A0A7I2YQY1|A0A7I2YQY1_HUMAN,tr|A0A7I2V523|A0A7I2V523_HUMAN,tr|A0A7I2V641|A0A7I2V641_HUMAN,tr|H7BZR6|H7BZR6_HUMAN,tr|A0A7I2V491|A0A7I2V491_HUMAN,tr|A0A7I2YQI9|A0A7I2YQI9_HUMAN,tr|C9J9M4|C9J9M4_HUMAN,tr|A0A7I2V262|A0A7I2V262_HUMAN,tr|A0A087WW66|A0A087WW66_HUMAN,tr|A0A7P0MW50|A0A7P0MW50_HUMAN,tr|A0A7I2V4A5|A0A7I2V4A5_HUMAN,tr|A0A7I2V5C8|A0A7I2V5C8_HUMAN,tr|A0A7I2V479|A0A7I2V479_HUMAN" 16 923.5195 0.56 45469 11002 2 923.514532 462.767 26S proteasome non-ATPase regulatory subunit 1 OS=Homo sapiens OX=9606 GN=PSMD1 PE=1 SV=2 6.07 2271 - 1.16E+06 - - - -5.4195 - 1.512 0.108 - 373.6 1 2 0 -0.005 7 0 0 0 1.55E+07 2.77E+07 - - - 1.1471 0.9998 221125_WJC_METTL3_EV_vs_WT_F04.11003.11003.2 0.00656 14/22 R.IAAENELNQSYK[136.11].L sp|O15397|IPO8_HUMAN 1 1386.6871 1.61 45470 11003 2 1386.685318 694.3508 Importin-8 OS=Homo sapiens OX=9606 GN=IPO8 PE=1 SV=2 4.53 2271.2 - 472117 - - - -1.2555 - 2.562 0.428 - 702.9 1 2 0 -0.0017 12 0 0 0 2.91E+07 1.81E+07 - - - 4.677 0.9991 221125_WJC_METTL3_EV_vs_WT_F04.11004.11004.2 0.00792 18-Aug R.IEISSPC[160.03]C[160.03]PR.Q sp|Q5T749|KPRP_HUMAN 1 1217.5533 0.35 45471 11004 2 1217.554608 609.7839 Keratinocyte proline-rich protein OS=Homo sapiens OX=9606 GN=KPRP PE=1 SV=1 5.99 2271.3 - 409190 - - - 1.0915 - 1.469 0.354 - 173.7 1 2 0 0.0013 10 0 0 0 1.58E+08 4.54E+08 - - - 2.7287 0.9992 221125_WJC_METTL3_EV_vs_WT_F04.11006.11006.2 0.000219 24-Nov R.SLGSAGPSGTLPR.S sp|Q8WUF5|IASPP_HUMAN 1 1198.6306 2.31 45472 11006 2 1198.627184 600.3226 RelA-associated inhibitor OS=Homo sapiens OX=9606 GN=PPP1R13L PE=1 SV=4 9.47 2271.5 - 671242 - - - -2.8499 - 2.081 0.421 - 346.2 1 2 0 -0.0034 13 0 0 0 6.13E+07 2.66E+07 - - - 4.0303 0.9994 221125_WJC_METTL3_EV_vs_WT_F04.11008.11008.2 2.17E-05 18-Oct K.QC[160.03]GNLTEDLK.T "sp|P52732|KIF11_HUMAN,tr|A0A7I2V3A9|A0A7I2V3A9_HUMAN" 2 1176.5445 4.25 45473 11008 2 1176.548335 589.2795 Kinesin-like protein KIF11 OS=Homo sapiens OX=9606 GN=KIF11 PE=1 SV=2 4.37 2271.7 - 2.00E+06 - - - 3.2697 - 2.317 0.519 - 258.8 1 2 0 0.0038 10 0 0 0 3.95E+08 9.30E+07 - - - 5.2186 0.9979 221125_WJC_METTL3_EV_vs_WT_F04.11009.11009.2 0.00391 16-Sep K.QILGVIDK[136.11]K[136.11].L "sp|Q14444|CAPR1_HUMAN,tr|E9PLA9|E9PLA9_HUMAN" 2 1028.6565 0.92 45474 11009 2 1028.659026 515.3355 Caprin-1 OS=Homo sapiens OX=9606 GN=CAPRIN1 PE=1 SV=2 8.59 2271.9 - 2.15E+06 - - - 2.4741 - 2.014 0.23 - 372.8 1 2 0 0.0025 9 0 0 0 6.37E+07 6.92E+07 - - - 2.7645 0.9064 221125_WJC_METTL3_EV_vs_WT_F04.11010.11010.2 4.92 12-May R.EHTLAWK[136.11].L "sp|P22102|PUR2_HUMAN,tr|F8WD69|F8WD69_HUMAN,tr|C9JKQ7|C9JKQ7_HUMAN,tr|C9JZG2|C9JZG2_HUMAN,tr|C9JTV6|C9JTV6_HUMAN,tr|C9JBJ1|C9JBJ1_HUMAN" 6 891.4694 0.01 45475 11010 2 891.46875 446.742 Trifunctional purine biosynthetic protein adenosine-3 OS=Homo sapiens OX=9606 GN=GART PE=1 SV=1 6.85 2272 - 1.21E+06 - - - -0.7314 - 0.914 0.06 - 103.9 1 2 0 -0.0007 7 0 0 0 1.36E+05 1.23E+07 - - - -0.801 0.9055 221125_WJC_METTL3_EV_vs_WT_F04.11011.11011.2 1.08 14-Jul R.IRITLTSR.N "sp|P60866|RS20_HUMAN,tr|E5RJX2|E5RJX2_HUMAN,tr|E5RIP1|E5RIP1_HUMAN,tr|A0A7P0S5H5|A0A7P0S5H5_HUMAN" 4 958.5924 1.29 45476 11011 2 958.594029 480.3035 40S ribosomal protein S20 OS=Homo sapiens OX=9606 GN=RPS20 PE=1 SV=1 12 2272.1 - 1.00E+06 - - - 1.7369 - 1.256 0.192 - 88.6 1 2 1 0.0017 8 0 0 0 1.36E+07 1.05E+07 - - - 1.146 0.979 221125_WJC_METTL3_EV_vs_WT_F04.11012.11012.2 6.96 16-Aug K.QILGVIDKK.L "sp|Q14444|CAPR1_HUMAN,tr|E9PLA9|E9PLA9_HUMAN" 2 1012.6281 0.92 45477 11012 2 1012.624134 507.3213 Caprin-1 OS=Homo sapiens OX=9606 GN=CAPRIN1 PE=1 SV=2 8.59 2272.2 - 970509 - - - -3.8978 - 1.532 0.183 - 206.9 1 2 0 -0.0039 9 0 0 0 6.37E+07 6.92E+07 - - - 1.6255 0.9998 221125_WJC_METTL3_EV_vs_WT_F04.11017.11017.2 1.42E-06 15/22 R.IAAENELNQSYK.L sp|O15397|IPO8_HUMAN 1 1378.6729 1.61 45480 11017 2 1378.669546 690.3437 Importin-8 OS=Homo sapiens OX=9606 GN=IPO8 PE=1 SV=2 4.53 2272.9 - 2.57E+06 - - - -2.403 - 3.084 0.487 - 841.5 1 2 0 -0.0033 12 0 0 0 2.91E+07 1.81E+07 - - - 5.6002 0.9997 221125_WJC_METTL3_EV_vs_WT_F04.11019.11019.2 0.0062 13/22 R.IQTQPGYANTLR[166.11].D "sp|Q00325|MPCP_HUMAN,tr|F8VVM2|F8VVM2_HUMAN" 2 1370.7182 0.81 45482 11019 2 1370.716578 686.3664 "Phosphate carrier protein, mitochondrial OS=Homo sapiens OX=9606 GN=SLC25A3 PE=1 SV=2" 8.75 2273.1 - 1.53E+06 - - - -1.1709 - 2.168 0.412 - 486.8 1 2 0 -0.0016 12 0 0 0 1.15E+08 1.42E+08 - - - 4.1195 0.9974 221125_WJC_METTL3_EV_vs_WT_F04.11020.11020.2 0.0841 12-Jun R.NFNLENR.A sp|Q9P032|NDUF4_HUMAN 1 905.4355 1.45 45483 11020 2 905.434723 453.725 NADH dehydrogenase [ubiquinone] 1 alpha subcomplex assembly factor 4 OS=Homo sapiens OX=9606 GN=NDUFAF4 PE=1 SV=1 6 2273.2 - 1.53E+06 - - - -0.8902 - 1.327 0.237 - 179.7 1 2 0 -0.0008 7 0 0 0 4.24E+07 2.91E+07 - - - 1.6877 0.9998 221125_WJC_METTL3_EV_vs_WT_F04.11022.11022.2 2.39E-06 24-Dec K.TTLSASGTGFGDK.F sp|P49790|NU153_HUMAN 1 1240.5935 0.72 45485 11022 2 1240.592957 621.304 Nuclear pore complex protein Nup153 OS=Homo sapiens OX=9606 GN=NUP153 PE=1 SV=2 5.5 2273.4 - 1.15E+06 - - - -0.4748 - 2.483 0.396 - 455 1 2 0 -0.0006 13 0 0 0 5.82E+07 8.12E+07 - - - 4.2998 0.9991 221125_WJC_METTL3_EV_vs_WT_F04.11023.11023.2 0.0084 18-Sep K.QC[160.03]GNLTEDLK[136.11].T "sp|P52732|KIF11_HUMAN,tr|A0A7I2V3A9|A0A7I2V3A9_HUMAN" 2 1184.5587 4.24 45486 11023 2 1184.55514 593.2866 Kinesin-like protein KIF11 OS=Homo sapiens OX=9606 GN=KIF11 PE=1 SV=2 4.37 2273.5 - 1.10E+06 - - - -2.9952 - 2.367 0.358 - 412.3 1 2 0 -0.0035 10 0 0 0 3.94E+08 9.30E+07 - - - 4.0891 0.9966 221125_WJC_METTL3_EV_vs_WT_F04.11024.11024.2 0.497 16-Sep R.TYLPSQVSR.V "sp|P35606|COPB2_HUMAN,tr|H0Y938|H0Y938_HUMAN,tr|A0A7I2V258|A0A7I2V258_HUMAN,tr|H0YAC7|H0YAC7_HUMAN" 4 1049.5506 0.89 45487 11024 2 1049.548543 525.7826 Coatomer subunit beta' OS=Homo sapiens OX=9606 GN=COPB2 PE=1 SV=2 8.41 2273.7 - 607875 - - - -1.9208 - 1.547 0.22 - 279 1 2 0 -0.002 9 0 0 0 3.02E+07 3.39E+07 - - - 1.9276 0.9998 221125_WJC_METTL3_EV_vs_WT_F04.11027.11027.2 0.00159 18-Sep R.STSSFSC[160.03]LSR.H sp|P35908|K22E_HUMAN 1 1130.5026 41.83 45488 11027 2 1130.501388 566.2586 "Keratin, type II cytoskeletal 2 epidermal OS=Homo sapiens OX=9606 GN=KRT2 PE=1 SV=2" 7.96 2274.1 - 2.47E+06 - - - -1.0924 - 2.108 0.473 - 468.3 1 2 0 -0.0012 10 0 0 0 4.05E+07 9.68E+05 - - - 4.6158 0.9996 221125_WJC_METTL3_EV_vs_WT_F04.11029.11029.3 0.00362 Dec-36 K.GTYLATFHQR.G "sp|P55884|EIF3B_HUMAN,tr|C9JQN7|C9JQN7_HUMAN" 2 1192.5989 1.02 45490 11029 3 1192.594574 398.5402 Eukaryotic translation initiation factor 3 subunit B OS=Homo sapiens OX=9606 GN=EIF3B PE=1 SV=3 8.75 2274.2 - 2.31E+06 - - - -3.6324 - 2.363 0.401 - 231 1 2 0 -0.0043 10 0 0 0 3.03E+07 2.97E+07 - - - 5.5209 0.9997 221125_WJC_METTL3_EV_vs_WT_F04.11030.11030.2 0.00619 13/22 R.IQTQPGYANTLR.D "sp|Q00325|MPCP_HUMAN,tr|F8VVM2|F8VVM2_HUMAN" 2 1360.7099 0.81 45491 11030 2 1360.707722 681.3622 "Phosphate carrier protein, mitochondrial OS=Homo sapiens OX=9606 GN=SLC25A3 PE=1 SV=2" 8.75 2274.3 - 1.95E+06 - - - -1.6102 - 2.348 0.402 - 479.2 1 2 0 -0.0022 12 0 0 0 1.15E+08 1.42E+08 - - - 4.2554 0.9996 221125_WJC_METTL3_EV_vs_WT_F04.11031.11031.3 0.0184 Nov-36 K.K[136.11]QLADETLLK[136.11].V "sp|P20700|LMNB1_HUMAN,tr|E9PBF6|E9PBF6_HUMAN,tr|A0A0D9SFE5|A0A0D9SFE5_HUMAN" 3 1173.694 0.9 45492 11031 3 1173.689588 392.2386 Lamin-B1 OS=Homo sapiens OX=9606 GN=LMNB1 PE=1 SV=2 6.07 2274.4 - 1.84E+06 - - - -3.7497 - 2.404 0.418 - 213.9 1 2 0 -0.0044 10 0 0 0 1.63E+07 1.82E+07 - - - 5.7607 0.9972 221125_WJC_METTL3_EV_vs_WT_F04.11032.11032.3 0.0178 Nov-40 R.AGLVGPEFHEK.L "sp|Q15149|PLEC_HUMAN,tr|H0YDN1|H0YDN1_HUMAN" 2 1182.6033 1.11 45493 11032 3 1182.601201 395.2084 Plectin OS=Homo sapiens OX=9606 GN=PLEC PE=1 SV=3 5.4 2274.5 - 1.71E+06 - - - -1.7943 - 1.881 0.231 - 107.7 1 2 0 -0.0021 11 0 0 0 3.72E+07 3.35E+07 - - - 2.9097 0.9909 221125_WJC_METTL3_EV_vs_WT_F04.11033.11033.3 0.0539 Sep-36 K.KQLADETLLK.V "sp|P20700|LMNB1_HUMAN,tr|E9PBF6|E9PBF6_HUMAN,tr|A0A0D9SFE5|A0A0D9SFE5_HUMAN" 3 1157.6656 0.9 45494 11033 3 1157.661845 386.8958 Lamin-B1 OS=Homo sapiens OX=9606 GN=LMNB1 PE=1 SV=2 6.07 2274.5 - 1.66E+06 - - - -3.2341 - 1.714 0.242 - 94.1 1 2 0 -0.0037 10 0 0 0 1.63E+07 1.82E+07 - - - 2.8106 0.9996 221125_WJC_METTL3_EV_vs_WT_F04.11034.11034.2 0.0186 22-Nov K.GGPSPGDVEAIK.N "sp|P09661|RU2A_HUMAN,tr|H0YMA0|H0YMA0_HUMAN,tr|H0YLR3|H0YLR3_HUMAN" 3 1125.5666 1.46 45495 11034 2 1125.564687 563.7906 U2 small nuclear ribonucleoprotein A' OS=Homo sapiens OX=9606 GN=SNRPA1 PE=1 SV=2 4.37 2274.6 - 1.52E+06 - - - -1.7023 - 1.951 0.43 - 397 1 2 0 -0.0019 12 0 0 0 4.46E+07 3.05E+07 - - - 3.9749 0.9999 221125_WJC_METTL3_EV_vs_WT_F04.11035.11035.3 3.69E-06 14/40 K.DLLHPSPEEEK[136.11].R sp|P42677|RS27_HUMAN 1 1300.639 0.59 45496 11035 3 1300.637471 434.5536 40S ribosomal protein S27 OS=Homo sapiens OX=9606 GN=RPS27 PE=1 SV=3 4.4 2274.7 - 1.05E+06 - - - -1.2109 - 2.121 0.438 - 201.3 1 2 0 -0.0016 11 0 0 0 5.58E+08 9.42E+08 - - - 5.5588 0.9995 221125_WJC_METTL3_EV_vs_WT_F04.11036.11036.2 0.0309 20-Nov K.FGISEPGNQEK[136.11].K "sp|P0DJD0|RGPD1_HUMAN,sp|Q7Z3J3|RGPD4_HUMAN,sp|O14715|RGPD8_HUMAN,sp|P49792|RBP2_HUMAN,sp|P0DJD1|RGPD2_HUMAN,sp|A6NKT7|RGPD3_HUMAN,sp|Q99666|RGPD5_HUMAN,tr|A0A286YES2|A0A286YES2_HUMAN,tr|F8VYC4|F8VYC4_HUMAN,tr|J3KNE0|J3KNE0_HUMAN,tr|A0A1W2PNU4|A0A1W2PNU4_HUMAN,tr|J3KQ37|J3KQ37_HUMAN" 12 1212.5866 1.09 45497 11036 2 1212.584389 607.3006 RANBP2-like and GRIP domain-containing protein 1 OS=Homo sapiens OX=9606 GN=RGPD1 PE=2 SV=1 4.53 2274.9 - 751071 - - - -1.8374 - 1.614 0.447 - 273 1 2 0 -0.0022 11 0 0 0 2.63E+07 2.41E+07 - - - 3.6369 1 221125_WJC_METTL3_EV_vs_WT_F04.11037.11037.2 3.11E-07 13/24 K.YANEVNSDAGAFK[136.11].N sp|Q9UHB9|SRP68_HUMAN 1 1392.6401 1.01 45498 11037 2 1392.639507 697.3273 Signal recognition particle subunit SRP68 OS=Homo sapiens OX=9606 GN=SRP68 PE=1 SV=2 4.37 2275 - 730889 - - - -0.4323 - 2.881 0.544 - 470 1 2 0 -0.0006 13 0 0 0 1.65E+07 1.62E+07 - - - 5.7745 0.9995 221125_WJC_METTL3_EV_vs_WT_F04.11039.11039.2 1.17E-05 18-Oct R.SNTPILVDGK.D "sp|P06744|G6PI_HUMAN,tr|A0A2R8Y6C7|A0A2R8Y6C7_HUMAN,tr|K7EP41|K7EP41_HUMAN,tr|A0A0J9YYH3|A0A0J9YYH3_HUMAN,tr|K7EQ48|K7EQ48_HUMAN,tr|A0A2U3TZU2|A0A2U3TZU2_HUMAN,tr|K7ERC6|K7ERC6_HUMAN,tr|A0A0J9YXP8|A0A0J9YXP8_HUMAN,tr|A0A0J9YX90|A0A0J9YX90_HUMAN,tr|K7EPY4|K7EPY4_HUMAN" 10 1042.5659 28.48 45500 11039 2 1042.563111 522.2902 Glucose-6-phosphate isomerase OS=Homo sapiens OX=9606 GN=GPI PE=1 SV=4 5.55 2275.3 - 442872 - - - -2.6512 - 1.954 0.49 - 386.7 1 2 0 -0.0028 10 0 0 0 1.17E+08 4.10E+06 - - - 4.5291 0.9999 221125_WJC_METTL3_EV_vs_WT_F04.11040.11040.2 9.25E-06 18-Sep K.NNALNPEEMR[166.11].R "sp|O60684|IMA7_HUMAN,tr|S4R3E5|S4R3E5_HUMAN" 2 1196.5483 0.08 45501 11040 2 1196.548261 599.2814 Importin subunit alpha-7 OS=Homo sapiens OX=9606 GN=KPNA6 PE=1 SV=1 4.53 2275.4 - 434231 - - - -0.0669 - 2.071 0.487 - 340.5 1 2 0 -0.0001 10 0 0 0 3.19E+05 3.90E+06 - - - 4.6701 0.9181 221125_WJC_METTL3_EV_vs_WT_F04.11041.11041.2 0.00372 18-Sep Q.VQEFC[160.03]DYGTK[136.11].E "sp|Q86U44|MTA70_HUMAN,tr|H0YFV6|H0YFV6_HUMAN" 2 1253.5478 0.001 45502 11041 2 1253.544264 627.7812 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 4.37 2275.5 - 386316 - - - -2.812 - 1.674 0.383 - 276 1 1 0 -0.0035 10 0 0 0 0.00E+00 6.61E+06 - - - 3.3069 0.9996 221125_WJC_METTL3_EV_vs_WT_F04.11046.11046.2 0.0103 16-Dec R.R[166.11]LAELSDYR[166.11].R sp|Q96PK6|RBM14_HUMAN 1 1141.5995 3.68 45505 11046 2 1141.599391 571.807 RNA-binding protein 14 OS=Homo sapiens OX=9606 GN=RBM14 PE=1 SV=2 6.07 2276.1 - 1.56E+06 - - - -0.0622 - 1.849 0.329 - 383.4 1 2 0 -0.0001 9 0 0 0 1.56E+08 4.24E+07 - - - 3.2492 0.9964 221125_WJC_METTL3_EV_vs_WT_F04.11047.11047.2 0.000923 22-Nov K.GGPSPGDVEAIK[136.11].N "sp|P09661|RU2A_HUMAN,tr|H0YMA0|H0YMA0_HUMAN,tr|H0YLR3|H0YLR3_HUMAN" 3 1133.5808 1.44 45506 11047 2 1133.575288 567.7977 U2 small nuclear ribonucleoprotein A' OS=Homo sapiens OX=9606 GN=SNRPA1 PE=1 SV=2 4.37 2276.2 - 1.52E+06 - - - -4.8651 - 1.933 0.444 - 392.6 1 2 0 -0.0055 12 0 0 0 4.39E+07 3.05E+07 - - - 4.0528 1 221125_WJC_METTL3_EV_vs_WT_F04.11048.11048.3 5.77E-06 14/44 R.YLMEEDEDAYKK.Q "sp|P46777|RL5_HUMAN,tr|A0A2R8Y6J3|A0A2R8Y6J3_HUMAN" 2 1532.6705 1.41 45507 11048 3 1532.671015 511.8974 60S ribosomal protein L5 OS=Homo sapiens OX=9606 GN=RPL5 PE=1 SV=3 4.18 2276.3 - 1.45E+06 - - - 0.3517 - 2.477 0.605 - 171.4 1 2 0 0.0005 12 0 0 0 3.14E+07 2.23E+07 - - - 7.7992 0.9943 221125_WJC_METTL3_EV_vs_WT_F04.11049.11049.2 6.22E-05 16-Sep K.LTMQNLNDR.L "sp|P08727|K1C19_HUMAN,sp|P19012|K1C15_HUMAN,sp|P13646|K1C13_HUMAN,tr|C9JM50|C9JM50_HUMAN,tr|K7ERE3|K7ERE3_HUMAN,tr|K7EQH6|K7EQH6_HUMAN" 6 1103.5393 63.12 45508 11049 2 1103.532952 552.7769 "Keratin, type I cytoskeletal 19 OS=Homo sapiens OX=9606 GN=KRT19 PE=1 SV=4" 5.84 2276.3 - 1.36E+06 - - - -5.7905 - 2.013 0.44 - 370 1 2 0 -0.0064 9 0 0 0 3.76E+07 5.95E+05 - - - 4.3129 0.9999 221125_WJC_METTL3_EV_vs_WT_F04.11050.11050.2 4.30E-06 20-Dec K.LITDLQDQNQK.M sp|P33176|KINH_HUMAN 1 1314.6779 0.89 45509 11050 2 1314.677179 658.3462 Kinesin-1 heavy chain OS=Homo sapiens OX=9606 GN=KIF5B PE=1 SV=1 4.21 2276.5 - 1.28E+06 - - - -0.5827 - 2.296 0.547 - 422.3 1 2 0 -0.0008 11 0 0 0 1.98E+07 2.21E+07 - - - 5.3294 0.9998 221125_WJC_METTL3_EV_vs_WT_F04.11051.11051.2 7.91E-06 13/22 R.FNEVAAQYSEDK[136.11].A "sp|Q9Y237|PIN4_HUMAN,tr|A0A494C021|A0A494C021_HUMAN,tr|H0Y610|H0Y610_HUMAN,tr|H0Y4T6|H0Y4T6_HUMAN,tr|H0Y8P6|H0Y8P6_HUMAN,tr|J3KMW3|J3KMW3_HUMAN" 6 1407.6398 1 45510 11051 2 1407.637273 704.8272 Peptidyl-prolyl cis-trans isomerase NIMA-interacting 4 OS=Homo sapiens OX=9606 GN=PIN4 PE=1 SV=1 4.14 2276.6 - 1.12E+06 - - - -1.7774 - 2.455 0.469 - 582.2 1 2 0 -0.0025 12 0 0 0 1.13E+07 1.13E+07 - - - 4.8674 1 221125_WJC_METTL3_EV_vs_WT_F04.11052.11052.2 6.48E-06 14/20 K.DLLHPSPEEEK[136.11].R sp|P42677|RS27_HUMAN 1 1300.639 0.65 45511 11052 2 1300.642579 651.3268 40S ribosomal protein S27 OS=Homo sapiens OX=9606 GN=RPS27 PE=1 SV=3 4.4 2276.7 - 550754 - - - 2.7164 - 2.74 0.551 - 487.7 1 2 0 0.0035 11 0 0 0 1.03E+08 1.58E+08 - - - 5.8363 0.9832 221125_WJC_METTL3_EV_vs_WT_F04.11053.11053.2 0.795 18-Oct K.ELQSVEQEVR[166.11].W "sp|Q969Z0|FAKD4_HUMAN,tr|C9IZN7|C9IZN7_HUMAN,tr|C9J7P5|C9J7P5_HUMAN" 3 1225.6178 0.86 45512 11053 2 1225.620069 613.8162 FAST kinase domain-containing protein 4 OS=Homo sapiens OX=9606 GN=TBRG4 PE=1 SV=1 4.25 2276.9 - 528662 - - - 1.8505 - 1.666 0.041 - 346.8 1 2 0 0.0023 10 0 0 0 6.95E+06 8.11E+06 - - - 0.7679 0.9742 221125_WJC_METTL3_EV_vs_WT_F04.11055.11055.2 1.35 12-Jul R.R[166.11]FVEIPR[166.11].E "sp|Q9Y6J9|TAF6L_HUMAN,tr|E9PLV8|E9PLV8_HUMAN,tr|E9PP94|E9PP94_HUMAN,tr|E9PK90|E9PK90_HUMAN" 4 935.5456 1.18 45514 11055 2 935.542826 468.7801 TAF6-like RNA polymerase II p300\CBP-associated factor-associated factor 65 kDa subunit 6L OS=Homo sapiens OX=9606 GN=TAF6L PE=1 SV=1 9.6 2277.1 - 515101 - - - -2.9395 - 1.471 0.094 - 125.3 1 2 0 -0.0027 7 0 0 0 9.13E+06 7.75E+06 - - - 0.9573 0.9999 221125_WJC_METTL3_EV_vs_WT_F04.11059.11059.3 0.00163 Dec-40 K.DLLHPSPEEEK.R sp|P42677|RS27_HUMAN 1 1292.6248 0.59 45516 11059 3 1292.622822 431.8822 40S ribosomal protein S27 OS=Homo sapiens OX=9606 GN=RPS27 PE=1 SV=3 4.4 2277.6 - 3.18E+06 - - - -1.5658 - 1.886 0.45 - 146.2 1 2 0 -0.002 11 0 0 0 5.55E+08 9.42E+08 - - - 5.3589 1 221125_WJC_METTL3_EV_vs_WT_F04.11060.11060.2 4.94E-05 15/24 K.YANEVNSDAGAFK.N sp|Q9UHB9|SRP68_HUMAN 1 1384.6259 1.01 45517 11060 2 1384.625371 693.3202 Signal recognition particle subunit SRP68 OS=Homo sapiens OX=9606 GN=SRP68 PE=1 SV=2 4.37 2277.8 - 1.47E+06 - - - -0.3886 - 3.133 0.604 - 713.7 1 2 0 -0.0005 13 0 0 0 1.65E+07 1.62E+07 - - - 6.4329 0.9969 221125_WJC_METTL3_EV_vs_WT_F04.11061.11061.2 0.0828 16-Aug K.DGVVEITGK.H "sp|P04792|HSPB1_HUMAN,tr|A0A6Q8PHJ6|A0A6Q8PHJ6_HUMAN,tr|A0A6Q8PFK8|A0A6Q8PFK8_HUMAN" 3 916.4866 2.83 45518 11061 2 916.486316 459.2506 Heat shock protein beta-1 OS=Homo sapiens OX=9606 GN=HSPB1 PE=1 SV=2 4.37 2277.8 - 3.00E+06 - - - -0.2684 - 1.436 0.186 - 214.5 1 2 0 -0.0002 9 0 0 0 3.27E+07 1.16E+07 - - - 1.4616 0.9998 221125_WJC_METTL3_EV_vs_WT_F04.11062.11062.2 1.75E-06 13/20 K.FGISEPGNQEK.K "sp|P0DJD0|RGPD1_HUMAN,sp|Q7Z3J3|RGPD4_HUMAN,sp|O14715|RGPD8_HUMAN,sp|P49792|RBP2_HUMAN,sp|P0DJD1|RGPD2_HUMAN,sp|A6NKT7|RGPD3_HUMAN,sp|Q99666|RGPD5_HUMAN,tr|A0A286YES2|A0A286YES2_HUMAN,tr|F8VYC4|F8VYC4_HUMAN,tr|J3KNE0|J3KNE0_HUMAN,tr|A0A1W2PNU4|A0A1W2PNU4_HUMAN,tr|J3KQ37|J3KQ37_HUMAN" 12 1204.5724 1.01 45519 11062 2 1204.570453 603.2935 RANBP2-like and GRIP domain-containing protein 1 OS=Homo sapiens OX=9606 GN=RGPD1 PE=2 SV=1 4.53 2277.9 - 1.63E+06 - - - -1.6305 - 2.509 0.459 - 432.5 1 2 0 -0.002 11 0 0 0 2.78E+07 2.74E+07 - - - 4.9191 0.9999 221125_WJC_METTL3_EV_vs_WT_F04.11063.11063.2 1.55E-05 20-Dec K.LITDLQDQNQK[136.11].M sp|P33176|KINH_HUMAN 1 1322.6921 1.09 45520 11063 2 1322.692074 662.3533 Kinesin-1 heavy chain OS=Homo sapiens OX=9606 GN=KIF5B PE=1 SV=1 4.21 2278 - 1.23E+06 - - - -0.0537 - 2.391 0.525 - 411.1 1 2 0 -0.0001 11 0 0 0 1.92E+07 1.76E+07 - - - 5.2768 0.9807 221125_WJC_METTL3_EV_vs_WT_F04.11064.11064.2 0.0112 16-Jul K.DGVVEITGK[136.11].H "sp|P04792|HSPB1_HUMAN,tr|A0A6Q8PHJ6|A0A6Q8PHJ6_HUMAN,tr|A0A6Q8PFK8|A0A6Q8PFK8_HUMAN" 3 924.5008 2.8 45521 11064 2 924.49527 463.2577 Heat shock protein beta-1 OS=Homo sapiens OX=9606 GN=HSPB1 PE=1 SV=2 4.37 2278.1 - 1.16E+06 - - - -5.9405 - 1.711 0.322 - 163.5 1 2 0 -0.0055 9 0 0 0 3.25E+07 1.16E+07 - - - 2.9714 0.9999 221125_WJC_METTL3_EV_vs_WT_F04.11066.11066.2 0.000714 22-Nov R.FNEVAAQYSEDK.A "sp|Q9Y237|PIN4_HUMAN,tr|A0A494C021|A0A494C021_HUMAN,tr|H0Y610|H0Y610_HUMAN,tr|H0Y4T6|H0Y4T6_HUMAN,tr|H0Y8P6|H0Y8P6_HUMAN,tr|J3KMW3|J3KMW3_HUMAN" 6 1399.6256 1 45523 11066 2 1399.625639 700.8201 Peptidyl-prolyl cis-trans isomerase NIMA-interacting 4 OS=Homo sapiens OX=9606 GN=PIN4 PE=1 SV=1 4.14 2278.3 - 1.02E+06 - - - 0.0457 - 2.477 0.534 - 357.6 1 2 0 0.0001 12 0 0 0 1.13E+07 1.13E+07 - - - 5.3717 0.9998 221125_WJC_METTL3_EV_vs_WT_F04.11070.11070.3 0.00358 Nov-44 R.YLMEEDEDAYK[136.11]K[136.11].Q "sp|P46777|RL5_HUMAN,tr|A0A2R8Y6J3|A0A2R8Y6J3_HUMAN" 2 1548.6989 1.08 45526 11070 3 1548.69748 517.2402 60S ribosomal protein L5 OS=Homo sapiens OX=9606 GN=RPL5 PE=1 SV=3 4.18 2278.8 - 3.09E+06 - - - -0.9014 - 1.538 0.426 - 102.3 1 2 0 -0.0014 12 0 0 0 2.77E+07 2.57E+07 - - - 4.4823 0.9997 221125_WJC_METTL3_EV_vs_WT_F04.11072.11072.2 3.08E-05 22-Nov K.AYVDDTPAEQMK[136.11].A "sp|P07814|SYEP_HUMAN,tr|V9GYZ6|V9GYZ6_HUMAN" 2 1374.6217 0.95 45527 11072 2 1374.622531 688.3181 Bifunctional glutamate\proline--tRNA ligase OS=Homo sapiens OX=9606 GN=EPRS1 PE=1 SV=5 4.03 2279 - 2.37E+06 - - - 0.6176 - 1.762 0.449 - 303.2 1 2 0 0.0008 12 0 0 0 3.27E+07 3.42E+07 - - - 3.8475 0.9998 221125_WJC_METTL3_EV_vs_WT_F04.11073.11073.3 0.0104 14/48 K.IGEVDVEQHTLAK[136.11].Y "sp|P14635|CCNB1_HUMAN,tr|H0YA62|H0YA62_HUMAN,tr|E9PC90|E9PC90_HUMAN" 3 1445.7606 3.53 45528 11073 3 1445.762692 482.9275 G2\mitotic-specific cyclin-B1 OS=Homo sapiens OX=9606 GN=CCNB1 PE=1 SV=1 4.65 2279.2 - 393733 - - - 1.476 - 2.346 0.374 - 136.8 1 2 0 0.0021 13 0 0 0 1.17E+07 3.31E+06 - - - 5.0211 0.9995 221125_WJC_METTL3_EV_vs_WT_F04.11074.11074.2 0.0061 16-Aug K.AEEDEILNR[166.11].S "sp|P27824|CALX_HUMAN,tr|A0A7P0T937|A0A7P0T937_HUMAN,tr|A0A7P0TB65|A0A7P0TB65_HUMAN,tr|A0A7P0TAE9|A0A7P0TAE9_HUMAN,tr|D6RGY2|D6RGY2_HUMAN,tr|A0A7P0Z484|A0A7P0Z484_HUMAN" 6 1097.5228 1.5 45529 11074 2 1097.522546 549.7687 Calnexin OS=Homo sapiens OX=9606 GN=CANX PE=1 SV=2 4 2279.3 - 758632 - - - -0.2661 - 1.558 0.367 - 226 1 2 0 -0.0003 9 0 0 0 2.81E+08 1.87E+08 - - - 3.0344 0.9372 221125_WJC_METTL3_EV_vs_WT_F04.11076.11076.2 0.00496 16-Jul L.LHPSPEEEK.R sp|P42677|RS27_HUMAN 1 1064.5138 0.53 45531 11076 2 1064.513982 533.2642 40S ribosomal protein S27 OS=Homo sapiens OX=9606 GN=RPS27 PE=1 SV=3 4.75 2279.5 - 419329 - - - 0.1343 - 1.478 0.286 - 171 1 1 0 0.0001 9 0 0 0 2.88E+07 5.48E+07 - - - 2.2836 0.9997 221125_WJC_METTL3_EV_vs_WT_F04.11078.11078.2 7.04E-05 22-Oct K.LSVQSNPSPQLR[166.11].S "sp|O75152|ZC11A_HUMAN,tr|E9PBY7|E9PBY7_HUMAN,tr|A0A1W2PPR9|A0A1W2PPR9_HUMAN,tr|E9PQ61|E9PQ61_HUMAN" 4 1334.7182 5.77 45533 11078 2 1334.719891 668.3664 Zinc finger CCCH domain-containing protein 11A OS=Homo sapiens OX=9606 GN=ZC3H11A PE=1 SV=3 9.75 2279.8 - 296980 - - - 1.2797 - 2.016 0.423 - 306.5 1 2 0 0.0017 12 0 0 0 8.38E+07 1.45E+07 - - - 4.0095 0.9998 221125_WJC_METTL3_EV_vs_WT_F04.11079.11079.2 3.93E-05 18-Sep K.YGFEPTQEGK[136.11].L sp|Q8IXM3|RM41_HUMAN 1 1162.5386 1.79 45534 11079 2 1162.538095 582.2766 "39S ribosomal protein L41, mitochondrial OS=Homo sapiens OX=9606 GN=MRPL41 PE=1 SV=1" 4.53 2279.9 - 290961 - - - -0.4378 - 1.77 0.464 - 223 1 2 0 -0.0005 10 0 0 0 1.56E+08 8.72E+07 - - - 4.0617 1 221125_WJC_METTL3_EV_vs_WT_F04.11080.11080.2 1.73E-05 28-Dec R.LQAALDDEEAGGRPA.M "sp|Q00839|HNRPU_HUMAN,tr|A0A1W2PPS1|A0A1W2PPS1_HUMAN,tr|A0A1X7SBS1|A0A1X7SBS1_HUMAN" 3 1511.7216 4.05 45535 11080 2 1511.720163 756.8681 Heterogeneous nuclear ribonucleoprotein U OS=Homo sapiens OX=9606 GN=HNRNPU PE=1 SV=6 3.92 2280.1 - 238865 - - - -0.9506 - 2.79 0.566 - 463.9 1 1 0 -0.0014 15 0 0 0 5.71E+06 1.41E+06 - - - 5.7436 0.9998 221125_WJC_METTL3_EV_vs_WT_F04.11084.11084.2 2.56E-05 20-Dec K.SLDVNQDSELK.F sp|Q99584|S10AD_HUMAN 1 1246.6041 2.05 45537 11084 2 1246.60492 624.3093 Protein S100-A13 OS=Homo sapiens OX=9606 GN=S100A13 PE=1 SV=1 4.03 2280.5 - 8.39E+06 - - - 0.649 - 2.289 0.452 - 403.3 1 2 0 0.0008 11 0 0 0 1.89E+08 9.22E+07 - - - 4.6195 0.9996 221125_WJC_METTL3_EV_vs_WT_F04.11085.11085.3 0.00139 Aug-40 K.IHPTSVISGYR[166.11].L "sp|P17987|TCPA_HUMAN,tr|F5H136|F5H136_HUMAN,tr|E7ERF2|E7ERF2_HUMAN,tr|F5H676|F5H676_HUMAN" 4 1238.6647 0.39 45538 11085 3 1238.664784 413.8955 T-complex protein 1 subunit alpha OS=Homo sapiens OX=9606 GN=TCP1 PE=1 SV=1 8.75 2280.6 - 4.25E+06 - - - 0.0751 - 1.733 0.353 - 101 1 2 0 0.0001 11 0 0 0 3.76E+08 9.56E+08 - - - 4.0376 0.8671 221125_WJC_METTL3_EV_vs_WT_F04.11086.11086.3 0.0369 Sep-40 K.PWSQHYHQGYY.- "sp|Q00839|HNRPU_HUMAN,tr|A0A1W2PPL4|A0A1W2PPL4_HUMAN,tr|A0A087WVI9|A0A087WVI9_HUMAN,tr|Q5RI18|Q5RI18_HUMAN,tr|A0A1W2PP35|A0A1W2PP35_HUMAN,tr|A0A1W2PPH7|A0A1W2PPH7_HUMAN,tr|A0A1W2PQD4|A0A1W2PQD4_HUMAN,tr|A0A1X7SBS1|A0A1X7SBS1_HUMAN" 8 1464.6211 - 45539 11086 3 1464.619422 489.2143 Heterogeneous nuclear ribonucleoprotein U OS=Homo sapiens OX=9606 GN=HNRNPU PE=1 SV=6 7.31 2280.6 - 3.22E+06 - - - -1.1443 - 1.154 0.372 - 57.4 1 1 0 -0.0017 11 0 0 0 - - - - - 3.0939 0.9966 221125_WJC_METTL3_EV_vs_WT_F04.11087.11087.2 1.27 14-Sep R.QVQLQLQK.Q "sp|Q9ULV3|CIZ1_HUMAN,tr|F5H2X7|F5H2X7_HUMAN,tr|H0Y5D5|H0Y5D5_HUMAN" 3 983.5764 2.95 45540 11087 2 983.575414 492.7955 Cip1-interacting zinc finger protein OS=Homo sapiens OX=9606 GN=CIZ1 PE=1 SV=2 8.75 2280.7 - 2.60E+06 - - - -0.9821 - 1.474 0.177 - 265.2 1 2 0 -0.001 8 0 0 0 2.35E+08 7.98E+07 - - - 1.5181 0.9999 221125_WJC_METTL3_EV_vs_WT_F04.11089.11089.2 1.70E-07 20-Nov K.DLLHPSPEEEK.R sp|P42677|RS27_HUMAN 1 1292.6248 0.65 45542 11089 2 1292.624822 647.3197 40S ribosomal protein S27 OS=Homo sapiens OX=9606 GN=RPS27 PE=1 SV=3 4.4 2280.8 - 1.33E+06 - - - -0.0186 - 2.457 0.526 - 293.9 1 2 0 0 11 0 0 0 9.64E+07 1.49E+08 - - - 5.3579 0.8641 221125_WJC_METTL3_EV_vs_WT_F04.11090.11090.2 0.00964 14-Jun L.AAFGQLHK[136.11].V sp|Q12906|ILF3_HUMAN 1 878.4854 0.35 45543 11090 2 878.483806 440.25 Interleukin enhancer-binding factor 3 OS=Homo sapiens OX=9606 GN=ILF3 PE=1 SV=3 8.8 2280.9 - 997633 - - - -1.7986 - 1.317 0.3 - 109 1 1 0 -0.0016 8 0 0 0 2.84E+07 8.04E+07 - - - 2.0868 0.9987 221125_WJC_METTL3_EV_vs_WT_F04.11092.11092.2 0.102 14-Jun K.DFSETYER[166.11].F "sp|Q96MH2|HEXI2_HUMAN,sp|O94992|HEXI1_HUMAN" 2 1055.4435 0.57 45545 11092 2 1055.444185 528.729 Protein HEXIM2 OS=Homo sapiens OX=9606 GN=HEXIM2 PE=1 SV=1 4.14 2281.1 - 770916 - - - 0.6253 - 1.19 0.361 - 111.8 1 2 0 0.0007 8 0 0 0 5.13E+06 8.99E+06 - - - 2.2318 0.9993 221125_WJC_METTL3_EV_vs_WT_F04.11095.11095.2 0.5 18-Sep K.ELQQQLVDAK.L sp|Q9NUQ3|TXLNG_HUMAN 1 1170.6245 1.6 45548 11095 2 1170.62212 586.3195 Gamma-taxilin OS=Homo sapiens OX=9606 GN=TXLNG PE=1 SV=2 4.37 2281.5 - 508014 - - - -1.9921 - 1.868 0.358 - 370.4 1 2 0 -0.0023 10 0 0 0 1.18E+07 7.41E+06 - - - 3.4287 0.9993 221125_WJC_METTL3_EV_vs_WT_F04.11096.11096.2 0.271 16-Sep K.KLADISLGK.E sp|Q02413|DSG1_HUMAN 1 943.5702 6.72 45549 11096 2 943.570093 472.7924 Desmoglein-1 OS=Homo sapiens OX=9606 GN=DSG1 PE=1 SV=2 8.59 2281.6 - 419190 - - - -0.1473 - 1.712 0.279 - 180.4 1 2 0 -0.0001 9 0 0 0 2.77E+07 4.11E+06 - - - 2.6571 0.9997 221125_WJC_METTL3_EV_vs_WT_F04.11101.11101.2 0.0575 18-Oct K.NVQLQENEIR.G "sp|P36873|PP1G_HUMAN,tr|A0A087WYY5|A0A087WYY5_HUMAN,tr|F8W0W8|F8W0W8_HUMAN,tr|F8VYE8|F8VYE8_HUMAN,tr|F8VR82|F8VR82_HUMAN" 5 1241.6364 0.98 45552 11101 2 1241.636616 621.8255 Serine\threonine-protein phosphatase PP1-gamma catalytic subunit OS=Homo sapiens OX=9606 GN=PPP1CC PE=1 SV=1 4.53 2282.3 - 2.48E+06 - - - 0.1627 - 2.062 0.334 - 428.2 1 2 0 0.0002 10 0 0 0 2.80E+07 2.85E+07 - - - 3.5279 0.9996 221125_WJC_METTL3_EV_vs_WT_F04.11104.11104.2 0.00246 20-Aug K.IHPTSVISGYR.L "sp|P17987|TCPA_HUMAN,tr|F5H136|F5H136_HUMAN,tr|E7ERF2|E7ERF2_HUMAN,tr|F5H676|F5H676_HUMAN" 4 1228.6564 0.42 45555 11104 2 1228.65606 615.3355 T-complex protein 1 subunit alpha OS=Homo sapiens OX=9606 GN=TCP1 PE=1 SV=1 8.75 2282.6 - 890532 - - - -0.2938 - 1.629 0.385 - 128.3 1 2 0 -0.0004 11 0 0 0 2.15E+08 5.12E+08 - - - 3.2046 1 221125_WJC_METTL3_EV_vs_WT_F04.11105.11105.2 0.000128 15/26 R.APSTYGGGLSVSSR.F sp|P08779|K1C16_HUMAN 1 1337.6575 999 45556 11105 2 1337.656971 669.836 "Keratin, type I cytoskeletal 16 OS=Homo sapiens OX=9606 GN=KRT16 PE=1 SV=4" 8.79 2282.8 - 706838 - - - -0.4276 - 2.834 0.556 - 761.5 1 2 0 -0.0006 14 0 0 0 1.20E+09 0.00E+00 - - - 5.7615 0.9984 221125_WJC_METTL3_EV_vs_WT_F04.11108.11108.3 0.0344 Nov-36 K.RLTELETAVR.C "sp|Q13561|DCTN2_HUMAN,tr|H0YI98|H0YI98_HUMAN,tr|A8K8J9|A8K8J9_HUMAN,tr|A0A7I2V5R4|A0A7I2V5R4_HUMAN,tr|F8W1I6|F8W1I6_HUMAN,tr|A0A7I2V390|A0A7I2V390_HUMAN,tr|A0A7I2V4Y9|A0A7I2V4Y9_HUMAN,tr|F8VRV7|F8VRV7_HUMAN,tr|F8VW18|F8VW18_HUMAN" 9 1186.667 0.31 45559 11108 3 1186.664861 396.5629 Dynactin subunit 2 OS=Homo sapiens OX=9606 GN=DCTN2 PE=1 SV=4 6.14 2283.1 - 467249 - - - -1.7907 - 2.144 0.225 - 171.4 1 2 0 -0.0021 10 0 0 0 4.92E+06 1.61E+07 - - - 3.2753 0.9998 221125_WJC_METTL3_EV_vs_WT_F04.11114.11114.2 0.00549 16-Dec K.AEEDEILNR.S "sp|P27824|CALX_HUMAN,tr|A0A7P0T937|A0A7P0T937_HUMAN,tr|A0A7P0TB65|A0A7P0TB65_HUMAN,tr|A0A7P0TAE9|A0A7P0TAE9_HUMAN,tr|D6RGY2|D6RGY2_HUMAN,tr|A0A7P0Z484|A0A7P0Z484_HUMAN" 6 1087.5146 1.5 45564 11114 2 1087.514122 544.7646 Calnexin OS=Homo sapiens OX=9606 GN=CANX PE=1 SV=2 4 2283.8 - 1.00E+07 - - - -0.4101 - 2.355 0.382 - 704.8 1 2 0 -0.0004 9 0 0 0 2.80E+08 1.87E+08 - - - 4.3403 0.9998 221125_WJC_METTL3_EV_vs_WT_F04.11116.11116.2 0.000119 20-Oct K.IHPTSVISGYR[166.11].L "sp|P17987|TCPA_HUMAN,tr|F5H136|F5H136_HUMAN,tr|E7ERF2|E7ERF2_HUMAN,tr|F5H676|F5H676_HUMAN" 4 1238.6647 0.42 45565 11116 2 1238.66365 620.3396 T-complex protein 1 subunit alpha OS=Homo sapiens OX=9606 GN=TCP1 PE=1 SV=1 8.75 2284 - 4.64E+06 - - - -0.8404 - 1.897 0.491 - 267.8 1 2 0 -0.001 11 0 0 0 2.15E+08 5.13E+08 - - - 4.3993 0.9999 221125_WJC_METTL3_EV_vs_WT_F04.11120.11120.2 1.40E-08 14/22 K.NSVVEASEAAYK[136.11].E "sp|Q04917|1433F_HUMAN,tr|A2IDB2|A2IDB2_HUMAN" 2 1274.6234 1.56 45569 11120 2 1274.621642 638.319 14-3-3 protein eta OS=Homo sapiens OX=9606 GN=YWHAH PE=1 SV=4 4.53 2284.4 - 1.08E+06 - - - -1.3761 - 2.825 0.486 - 891.8 1 2 0 -0.0018 12 0 0 0 3.62E+07 2.33E+07 - - - 5.3625 1 221125_WJC_METTL3_EV_vs_WT_F04.11121.11121.2 2.12E-07 14/24 K.LQNSASATALVSR[166.11].T sp|Q86YP4|P66A_HUMAN 1 1326.7131 1.43 45570 11121 2 1326.713244 664.3638 Transcriptional repressor p66-alpha OS=Homo sapiens OX=9606 GN=GATAD2A PE=1 SV=1 9.75 2284.5 - 962848 - - - 0.11 - 2.96 0.565 - 828.9 1 2 0 0.0001 13 0 0 0 1.26E+08 8.83E+07 - - - 5.9992 0.9998 221125_WJC_METTL3_EV_vs_WT_F04.11122.11122.3 0.00969 15/40 R.LALLHEGTGPR[166.11].V sp|Q9UQE7|SMC3_HUMAN 1 1172.6541 1.01 45571 11122 3 1172.652197 391.892 Structural maintenance of chromosomes protein 3 OS=Homo sapiens OX=9606 GN=SMC3 PE=1 SV=2 6.75 2284.6 - 685029 - - - -1.645 - 2.259 0.359 - 279.2 1 2 0 -0.0019 11 0 0 0 3.05E+07 3.01E+07 - - - 4.857 0.9992 221125_WJC_METTL3_EV_vs_WT_F04.11124.11124.2 0.0258 16-Sep K.TIVFVETK[136.11]R[166.11].R "sp|P17844|DDX5_HUMAN,tr|A0A7I2V5F5|A0A7I2V5F5_HUMAN,tr|J3QSF1|J3QSF1_HUMAN,tr|A0A7I2V507|A0A7I2V507_HUMAN,tr|J3KTA4|J3KTA4_HUMAN,tr|A0A0G2JLI4|A0A0G2JLI4_HUMAN,tr|A0A7I2V2S0|A0A7I2V2S0_HUMAN" 7 1109.6564 1.64 45573 11124 2 1109.655982 555.8355 Probable ATP-dependent RNA helicase DDX5 OS=Homo sapiens OX=9606 GN=DDX5 PE=1 SV=1 8.41 2284.9 - 436750 - - - -0.3452 - 1.673 0.284 - 338 1 2 0 -0.0004 9 0 0 0 9.35E+06 5.70E+06 - - - 2.6273 0.9977 221125_WJC_METTL3_EV_vs_WT_F04.11127.11127.3 0.0338 Nov-48 K.LRPVAAEVYGTER.Q "sp|P02788|TRFL_HUMAN,tr|C9JCF5|C9JCF5_HUMAN,tr|E7EQB2|E7EQB2_HUMAN,tr|E7ER44|E7ER44_HUMAN" 4 1459.7783 7.49 45574 11127 3 1459.776509 487.6001 Lactotransferrin OS=Homo sapiens OX=9606 GN=LTF PE=1 SV=6 6.14 2285.3 - 3.07E+06 - - - -1.2454 - 1.329 0.315 - 71.2 1 2 0 -0.0018 13 0 0 0 4.72E+07 6.30E+06 - - - 2.8226 1 221125_WJC_METTL3_EV_vs_WT_F04.11128.11128.3 3.16E-08 17/40 R.ILR[166.11]PWQSSETR[166.11].S "sp|Q15637|SF01_HUMAN,tr|A0A7P0T9U7|A0A7P0T9U7_HUMAN" 2 1391.7424 1.09 45575 11128 3 1391.739947 464.9214 Splicing factor 1 OS=Homo sapiens OX=9606 GN=SF1 PE=1 SV=4 9.6 2285.4 - 2.17E+06 - - - -1.7898 - 3.196 0.574 - 594.7 1 2 0 -0.0025 11 0 0 0 1.97E+08 1.82E+08 - - - 8.2396 0.9753 221125_WJC_METTL3_EV_vs_WT_F04.11130.11130.2 4.54E-05 18-Oct K.QYNGVPLDGR.P "sp|Q86V81|THOC4_HUMAN,tr|E9PB61|E9PB61_HUMAN" 2 1117.5516 0.66 45577 11130 2 1117.549194 559.7831 THO complex subunit 4 OS=Homo sapiens OX=9606 GN=ALYREF PE=1 SV=3 5.84 2285.5 - 3.11E+06 - - - -2.1726 - 1.693 0.511 - 275.6 1 1 0 -0.0024 10 0 0 0 4.32E+08 6.59E+08 - - - 4.2841 1 221125_WJC_METTL3_EV_vs_WT_F04.11131.11131.3 9.97E-06 14/40 R.ILRPWQSSETR.S "sp|Q15637|SF01_HUMAN,tr|A0A7P0T9U7|A0A7P0T9U7_HUMAN" 2 1371.7259 1.04 45578 11131 3 1371.724224 458.2492 Splicing factor 1 OS=Homo sapiens OX=9606 GN=SF1 PE=1 SV=4 9.6 2285.6 - 1.59E+06 - - - -1.2204 - 2.809 0.455 - 373.8 1 2 0 -0.0017 11 0 0 0 1.89E+08 1.81E+08 - - - 6.5464 0.9993 221125_WJC_METTL3_EV_vs_WT_F04.11132.11132.3 0.0435 13/40 R.LALLHEGTGPR.V sp|Q9UQE7|SMC3_HUMAN 1 1162.6459 1.04 45579 11132 3 1162.644696 388.5559 Structural maintenance of chromosomes protein 3 OS=Homo sapiens OX=9606 GN=SMC3 PE=1 SV=2 6.75 2285.7 - 1.12E+06 - - - -0.9977 - 2.297 0.239 - 211.5 1 2 0 -0.0012 11 0 0 0 3.17E+07 3.05E+07 - - - 3.5667 0.9984 221125_WJC_METTL3_EV_vs_WT_F04.11133.11133.2 0.000628 14-Jul K.SSQAFFSK[136.11].L sp|O00566|MPP10_HUMAN 1 908.4483 1.51 45580 11133 2 908.447182 455.2314 U3 small nucleolar ribonucleoprotein protein MPP10 OS=Homo sapiens OX=9606 GN=MPHOSPH10 PE=1 SV=2 8.47 2285.8 - 548335 - - - -1.2659 - 1.486 0.272 - 211.3 1 2 0 -0.0011 8 0 0 0 9.48E+07 6.27E+07 - - - 2.2442 0.9998 221125_WJC_METTL3_EV_vs_WT_F04.11136.11136.2 0.0017 14-Nov K.HLTDAYFK.K sp|Q02878|RL6_HUMAN 1 993.492 1.02 45581 11136 2 993.490777 497.7533 60S ribosomal protein L6 OS=Homo sapiens OX=9606 GN=RPL6 PE=1 SV=3 6.74 2286.2 - 4.60E+06 - - - -1.2129 - 1.887 0.509 - 486.8 1 2 0 -0.0012 8 0 0 0 1.05E+08 1.02E+08 - - - 4.7152 0.9998 221125_WJC_METTL3_EV_vs_WT_F04.11137.11137.2 6.91E-06 16-Oct K.DVNQQEFVR[166.11].A "sp|P39019|RS19_HUMAN,tr|M0R140|M0R140_HUMAN,tr|M0R2L9|M0R2L9_HUMAN,tr|M0QYF7|M0QYF7_HUMAN" 4 1143.5548 1.13 45582 11137 2 1143.552794 572.7847 40S ribosomal protein S19 OS=Homo sapiens OX=9606 GN=RPS19 PE=1 SV=2 4.37 2286.3 - 1.54E+06 - - - -1.7594 - 1.926 0.52 - 395.9 1 2 0 -0.002 9 0 0 0 8.19E+09 7.27E+09 - - - 4.7773 0.9997 221125_WJC_METTL3_EV_vs_WT_F04.11140.11140.2 0.00214 20-Aug R.TEEGPTLSYGR.D "sp|P43243|MATR3_HUMAN,tr|A8MXP9|A8MXP9_HUMAN,tr|D6R991|D6R991_HUMAN,tr|A0A0R4J2E8|A0A0R4J2E8_HUMAN,tr|D6REM6|D6REM6_HUMAN" 5 1208.5673 1.35 45583 11140 2 1208.565489 605.2909 Matrin-3 OS=Homo sapiens OX=9606 GN=MATR3 PE=1 SV=2 4.53 2286.7 - 4.01E+07 - - - -1.5241 - 2.128 0.422 - 200.4 1 2 0 -0.0018 11 0 0 0 6.46E+09 4.79E+09 - - - 4.2003 0.9948 221125_WJC_METTL3_EV_vs_WT_F04.11141.11141.2 6.27E-06 16-Oct K.DVNQQEFVR.A "sp|P39019|RS19_HUMAN,tr|M0R140|M0R140_HUMAN,tr|M0R2L9|M0R2L9_HUMAN,tr|M0QYF7|M0QYF7_HUMAN" 4 1133.5465 1.13 45584 11141 2 1133.539406 567.7805 40S ribosomal protein S19 OS=Homo sapiens OX=9606 GN=RPS19 PE=1 SV=2 4.37 2286.8 - 1.27E+06 - - - -6.29 - 2.044 0.53 - 391.9 1 2 0 -0.0071 9 0 0 0 8.19E+09 7.27E+09 - - - 5.0216 0.9999 221125_WJC_METTL3_EV_vs_WT_F04.11142.11142.3 0.000413 13/44 R.LQPHPQLSPEIR[166.11].R sp|Q13895|BYST_HUMAN 1 1423.7811 0.95 45585 11142 3 1423.779302 475.601 Bystin OS=Homo sapiens OX=9606 GN=BYSL PE=1 SV=3 6.75 2286.9 - 1.88E+06 - - - -1.2755 - 2.399 0.395 - 248.8 1 2 0 -0.0018 12 0 0 0 7.21E+07 7.59E+07 - - - 5.3689 0.9996 221125_WJC_METTL3_EV_vs_WT_F04.11143.11143.2 0.00851 16-Aug K.TIVFVETKR.R "sp|P17844|DDX5_HUMAN,tr|A0A7I2V5F5|A0A7I2V5F5_HUMAN,tr|J3QSF1|J3QSF1_HUMAN,tr|A0A7I2V507|A0A7I2V507_HUMAN,tr|J3KTA4|J3KTA4_HUMAN,tr|A0A0G2JLI4|A0A0G2JLI4_HUMAN,tr|A0A7I2V2S0|A0A7I2V2S0_HUMAN" 7 1091.6339 1.64 45586 11143 2 1091.63388 546.8242 Probable ATP-dependent RNA helicase DDX5 OS=Homo sapiens OX=9606 GN=DDX5 PE=1 SV=1 8.41 2287 - 750906 - - - -0.0137 - 1.909 0.333 - 240 1 2 0 0 9 0 0 0 9.35E+06 5.70E+06 - - - 3.3711 0.9834 221125_WJC_METTL3_EV_vs_WT_F04.11148.11148.2 0.195 16-Aug K.GYTIPLDK[136.11]R[166.11].L "sp|Q13573|SNW1_HUMAN,tr|G3V4X8|G3V4X8_HUMAN,tr|G3V3A4|G3V3A4_HUMAN,tr|G3V5R3|G3V5R3_HUMAN" 4 1079.6094 0.99 45589 11148 2 1079.606865 540.812 SNW domain-containing protein 1 OS=Homo sapiens OX=9606 GN=SNW1 PE=1 SV=1 8.59 2287.7 - 591045 - - - -2.362 - 1.33 0.15 - 214.3 1 2 0 -0.0025 9 0 0 0 1.98E+07 2.00E+07 - - - 0.9731 0.9999 221125_WJC_METTL3_EV_vs_WT_F04.11149.11149.3 0.00146 14/44 R.LQPHPQLSPEIR.R sp|Q13895|BYST_HUMAN 1 1413.7728 0.95 45590 11149 3 1413.771025 472.2649 Bystin OS=Homo sapiens OX=9606 GN=BYSL PE=1 SV=3 6.75 2287.7 - 1.68E+06 - - - -1.2895 - 2.327 0.371 - 272.6 1 2 0 -0.0018 12 0 0 0 7.21E+07 7.59E+07 - - - 5.0168 0.9468 221125_WJC_METTL3_EV_vs_WT_F04.11150.11150.2 0.195 20-Nov K.EIQAPASADIR[166.11].V sp|O43818|U3IP2_HUMAN 1 1179.6123 0.97 45591 11150 2 1179.618258 590.8134 U3 small nucleolar RNA-interacting protein 2 OS=Homo sapiens OX=9606 GN=RRP9 PE=1 SV=1 4.37 2287.9 - 1.57E+06 - - - 5.033 - 1.744 0.135 - 297.5 1 2 0 0.0059 11 0 0 0 2.75E+08 2.83E+08 - - - 1.5408 0.9995 221125_WJC_METTL3_EV_vs_WT_F04.11151.11151.2 0.000118 13/24 R.SVSLTGAPESVQK[136.11].A "sp|Q92945|FUBP2_HUMAN,tr|M0R0I5|M0R0I5_HUMAN,tr|M0QYH3|M0QYH3_HUMAN,tr|M0R0C6|M0R0C6_HUMAN,tr|M0QXW7|M0QXW7_HUMAN,tr|A0A087WTP3|A0A087WTP3_HUMAN" 6 1309.6969 0.99 45592 11151 2 1309.694115 655.8557 Far upstream element-binding protein 2 OS=Homo sapiens OX=9606 GN=KHSRP PE=1 SV=4 5.72 2288 - 947459 - - - -2.1234 - 2.017 0.427 - 553.2 1 2 0 -0.0028 13 0 0 0 2.26E+07 2.28E+07 - - - 3.9947 0.9997 221125_WJC_METTL3_EV_vs_WT_F04.11154.11154.2 6.43E-05 20-Sep R.YQDLGAYSSAR.K "sp|O96000|NDUBA_HUMAN,tr|H3BPJ9|H3BPJ9_HUMAN" 2 1229.5677 1.72 45593 11154 2 1229.566141 615.7911 NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 10 OS=Homo sapiens OX=9606 GN=NDUFB10 PE=1 SV=3 5.83 2288.4 - 3.76E+06 - - - -1.2403 - 1.682 0.492 - 208.7 1 2 0 -0.0015 11 0 0 0 1.24E+08 7.22E+07 - - - 4.0811 0.9994 221125_WJC_METTL3_EV_vs_WT_F04.11156.11156.2 0.00396 14-Aug K.SSQAFFSK.L sp|O00566|MPP10_HUMAN 1 900.4341 1.51 45595 11156 2 900.432222 451.2243 U3 small nucleolar ribonucleoprotein protein MPP10 OS=Homo sapiens OX=9606 GN=MPHOSPH10 PE=1 SV=2 8.47 2288.6 - 2.48E+06 - - - -2.1212 - 1.672 0.445 - 284 1 2 0 -0.0019 8 0 0 0 9.48E+07 6.27E+07 - - - 3.8774 0.9967 221125_WJC_METTL3_EV_vs_WT_F04.11159.11159.2 0.0211 18-Aug R.SLPNEEIVQK[136.11].L "sp|P18583|SON_HUMAN,tr|J3QSZ5|J3QSZ5_HUMAN" 2 1163.6278 1.75 45596 11159 2 1163.624437 582.8212 Protein SON OS=Homo sapiens OX=9606 GN=SON PE=1 SV=4 4.53 2289 - 2.60E+06 - - - -2.8497 - 1.575 0.303 - 166.1 1 2 0 -0.0033 10 0 0 0 2.30E+08 1.31E+08 - - - 2.5459 0.9953 221125_WJC_METTL3_EV_vs_WT_F04.11160.11160.3 0.00248 14/40 K.MLIEK[136.11]DPSLEK[136.11].S "sp|Q8NEY8|PPHLN_HUMAN,tr|B7Z8L1|B7Z8L1_HUMAN,tr|F8W6A0|F8W6A0_HUMAN,tr|F8W0Q9|F8W0Q9_HUMAN,tr|F8WF16|F8WF16_HUMAN" 5 1317.7185 1.17 45597 11160 3 1317.71461 440.2468 Periphilin-1 OS=Homo sapiens OX=9606 GN=PPHLN1 PE=1 SV=2 4.68 2289.1 - 1.64E+06 - - - -2.9437 - 2.338 0.297 - 233.9 1 2 1 -0.0039 11 0 0 0 9.93E+07 8.48E+07 - - - 4.2629 0.8629 221125_WJC_METTL3_EV_vs_WT_F04.11161.11161.3 0.0169 Dec-36 F.IDK[136.11]PVC[160.03]FVGR[166.11].L sp|P35244|RFA3_HUMAN 1 1207.6502 1.08 45598 11161 3 1207.64638 403.5574 Replication protein A 14 kDa subunit OS=Homo sapiens OX=9606 GN=RPA3 PE=1 SV=1 8.22 2289.2 - 1.14E+06 - - - -3.1913 - 2.018 0.315 - 160.7 1 1 0 -0.0039 10 0 0 0 2.34E+07 2.16E+07 - - - 4.1013 0.9686 221125_WJC_METTL3_EV_vs_WT_F04.11162.11162.3 0.15 Oct-48 K.VIMVTGDHPITAK.A "sp|P05023|AT1A1_HUMAN,sp|P13637|AT1A3_HUMAN,sp|Q13733|AT1A4_HUMAN,sp|P50993|AT1A2_HUMAN,sp|P54707|AT12A_HUMAN,sp|P20648|ATP4A_HUMAN,tr|A0A0A0MT26|A0A0A0MT26_HUMAN,tr|H0Y7C1|H0Y7C1_HUMAN,tr|A0A2R8YEY8|A0A2R8YEY8_HUMAN,tr|B1AKY9|B1AKY9_HUMAN,tr|M0R116|M0R116_HUMAN" 11 1380.7435 1.24 45599 11162 3 1380.738191 461.2551 Sodium\potassium-transporting ATPase subunit alpha-1 OS=Homo sapiens OX=9606 GN=ATP1A1 PE=1 SV=1 6.71 2289.3 - 464131 - - - -3.861 - 1.398 0.255 - 98 1 2 0 -0.0053 13 0 0 0 5.14E+07 4.14E+07 - - - 2.2899 0.9969 221125_WJC_METTL3_EV_vs_WT_F04.11168.11168.2 0.0149 20-Sep K.LSSNAVSQITR[166.11].M sp|Q9BQ39|DDX50_HUMAN 1 1184.6389 0.71 45603 11168 2 1184.636069 593.3267 ATP-dependent RNA helicase DDX50 OS=Homo sapiens OX=9606 GN=DDX50 PE=1 SV=1 9.75 2290 - 323986 - - - -2.3644 - 1.645 0.257 - 174.8 1 2 0 -0.0028 11 0 0 0 7.53E+06 1.07E+07 - - - 2.2848 0.9973 221125_WJC_METTL3_EV_vs_WT_F04.11179.11179.2 0.000155 22-Nov K.AATDGADTPFGR[166.11].S "sp|Q8WUF5|IASPP_HUMAN,tr|K7EN03|K7EN03_HUMAN" 2 1187.5446 5.51 45610 11179 2 1187.539038 594.7796 RelA-associated inhibitor OS=Homo sapiens OX=9606 GN=PPP1R13L PE=1 SV=4 4.21 2291.4 - 552604 - - - -4.7139 - 1.918 0.476 - 183.6 1 2 0 -0.0056 12 0 0 0 5.44E+07 9.88E+06 - - - 4.2686 0.9998 221125_WJC_METTL3_EV_vs_WT_F04.11184.11184.2 0.000157 18-Oct R.GVPQQIEVAR.Q sp|Q96I24|FUBP3_HUMAN 1 1095.6037 1.82 45613 11184 2 1095.602881 548.8091 Far upstream element-binding protein 3 OS=Homo sapiens OX=9606 GN=FUBP3 PE=1 SV=2 6 2292 - 1.69E+06 - - - -0.7083 - 1.823 0.432 - 470.3 1 2 0 -0.0008 10 0 0 0 4.11E+08 2.26E+08 - - - 3.9076 0.9998 221125_WJC_METTL3_EV_vs_WT_F04.11190.11190.3 0.00462 13/36 R.LSEGFSIHTR[166.11].D sp|P20618|PSB1_HUMAN 1 1155.5912 1.06 45617 11190 3 1155.588007 386.2043 Proteasome subunit beta type-1 OS=Homo sapiens OX=9606 GN=PSMB1 PE=1 SV=2 6.75 2292.8 - 804248 - - - -2.7562 - 2.6 0.386 - 199.2 1 2 0 -0.0032 10 0 0 0 7.21E+07 6.79E+07 - - - 5.6331 0.9991 221125_WJC_METTL3_EV_vs_WT_F04.11191.11191.2 4.43E-05 18-Sep R.MLVEYTQNQK[136.11].D "sp|Q9NQG5|RPR1B_HUMAN,tr|A2A2M0|A2A2M0_HUMAN,tr|A0A087WUK3|A0A087WUK3_HUMAN,tr|A0A087X2D2|A0A087X2D2_HUMAN" 4 1260.6264 1.96 45618 11191 2 1260.622504 631.3205 Regulation of nuclear pre-mRNA domain-containing protein 1B OS=Homo sapiens OX=9606 GN=RPRD1B PE=1 SV=1 5.75 2292.9 - 1.19E+06 - - - -3.0691 - 1.909 0.457 - 206.4 1 2 0 -0.0039 10 0 0 0 1.78E+08 9.12E+07 - - - 4.22 0.9996 221125_WJC_METTL3_EV_vs_WT_F04.11196.11196.2 0.00485 20-Nov R.GTGIVSAPVPK.K "sp|P15880|RS2_HUMAN,tr|I3L404|I3L404_HUMAN,tr|E9PM36|E9PM36_HUMAN,tr|E9PQD7|E9PQD7_HUMAN,tr|E9PMM9|E9PMM9_HUMAN,tr|H0YEN5|H0YEN5_HUMAN" 6 1024.5917 1.03 45621 11196 2 1024.590161 513.3031 40S ribosomal protein S2 OS=Homo sapiens OX=9606 GN=RPS2 PE=1 SV=2 8.75 2293.6 - 3.88E+06 - - - -1.4982 - 1.906 0.409 - 439.8 1 2 0 -0.0015 11 0 0 0 2.79E+08 2.70E+08 - - - 3.8063 0.9995 221125_WJC_METTL3_EV_vs_WT_F04.11197.11197.2 1.63E-05 18-Aug K.YSQYQQAIYK.C "sp|O14744|ANM5_HUMAN,tr|H0YJ77|H0YJ77_HUMAN,tr|G3V5T6|G3V5T6_HUMAN,tr|H0YJX6|H0YJX6_HUMAN" 4 1290.6245 2.36 45622 11197 2 1290.620314 646.3195 Protein arginine N-methyltransferase 5 OS=Homo sapiens OX=9606 GN=PRMT5 PE=1 SV=4 8.43 2293.6 - 2.43E+06 - - - -3.2062 - 1.94 0.574 - 156.7 1 2 0 -0.0041 10 0 0 0 8.69E+08 3.68E+08 - - - 5.129 0.9908 221125_WJC_METTL3_EV_vs_WT_F04.11201.11201.2 0.857 16-Sep K.LQEQVTDLR.S sp|P12270|TPR_HUMAN 1 1100.5826 26.57 45626 11201 2 1100.587496 551.2986 Nucleoprotein TPR OS=Homo sapiens OX=9606 GN=TPR PE=1 SV=3 4.37 2294.1 - 885660 - - - 4.4595 - 1.863 0.252 - 298.5 1 2 0 0.0049 9 0 0 0 2.45E+07 9.22E+05 - - - 2.7008 0.9955 221125_WJC_METTL3_EV_vs_WT_F04.11204.11204.3 0.04 14/40 K.MLIEKDPSLEK.S "sp|Q8NEY8|PPHLN_HUMAN,tr|B7Z8L1|B7Z8L1_HUMAN,tr|F8W6A0|F8W6A0_HUMAN,tr|F8W0Q9|F8W0Q9_HUMAN,tr|F8WF16|F8WF16_HUMAN" 5 1301.6901 1.29 45627 11204 3 1301.687455 434.904 Periphilin-1 OS=Homo sapiens OX=9606 GN=PPHLN1 PE=1 SV=2 4.68 2294.4 - 4.44E+06 - - - -2.0235 - 2.276 0.26 - 245.3 1 2 1 -0.0026 11 0 0 0 9.93E+07 7.67E+07 - - - 3.7744 0.9992 221125_WJC_METTL3_EV_vs_WT_F04.11205.11205.2 0.00152 18-Sep R.MLVEYTQNQK.D "sp|Q9NQG5|RPR1B_HUMAN,tr|A2A2M0|A2A2M0_HUMAN,tr|A0A087WUK3|A0A087WUK3_HUMAN,tr|A0A087X2D2|A0A087X2D2_HUMAN" 4 1252.6122 1.91 45628 11205 2 1252.608574 627.3134 Regulation of nuclear pre-mRNA domain-containing protein 1B OS=Homo sapiens OX=9606 GN=RPRD1B PE=1 SV=1 5.75 2294.5 - 4.39E+06 - - - -2.8732 - 1.684 0.48 - 215.2 1 2 0 -0.0036 10 0 0 0 1.74E+08 9.12E+07 - - - 4.0399 0.9999 221125_WJC_METTL3_EV_vs_WT_F04.11206.11206.2 8.23E-08 18-Oct K.YSQYQQAIYK[136.11].C "sp|O14744|ANM5_HUMAN,tr|H0YJ77|H0YJ77_HUMAN,tr|G3V5T6|G3V5T6_HUMAN,tr|H0YJX6|H0YJX6_HUMAN" 4 1298.6387 2.43 45629 11206 2 1298.636925 650.3266 Protein arginine N-methyltransferase 5 OS=Homo sapiens OX=9606 GN=PRMT5 PE=1 SV=4 8.43 2294.6 - 2.47E+06 - - - -1.3299 - 2.139 0.58 - 278.4 1 2 0 -0.0017 10 0 0 0 8.62E+08 3.55E+08 - - - 5.4467 0.9996 221125_WJC_METTL3_EV_vs_WT_F04.11207.11207.3 0.00044 Dec-36 R.DLYDDKDGLR.K sp|Q12874|SF3A3_HUMAN 1 1208.5673 4 45630 11207 3 1208.564933 403.8631 Splicing factor 3A subunit 3 OS=Homo sapiens OX=9606 GN=SF3A3 PE=1 SV=1 4.14 2294.7 - 1.76E+06 - - - -1.9842 - 2.257 0.46 - 234.8 1 2 1 -0.0024 10 0 0 0 1.13E+08 2.82E+07 - - - 6.0452 0.9996 221125_WJC_METTL3_EV_vs_WT_F04.11208.11208.3 0.00024 13/36 R.LSEGFSIHTR.D sp|P20618|PSB1_HUMAN 1 1145.5829 1.06 45631 11208 3 1145.580058 382.8683 Proteasome subunit beta type-1 OS=Homo sapiens OX=9606 GN=PSMB1 PE=1 SV=2 6.75 2294.7 - 1.73E+06 - - - -2.5 - 2.36 0.336 - 196.9 1 2 0 -0.0029 10 0 0 0 7.22E+07 6.80E+07 - - - 4.7929 0.9987 221125_WJC_METTL3_EV_vs_WT_F04.11210.11210.2 0.0529 18-Aug K.STIQTAEALR.L "sp|Q16875|F263_HUMAN,tr|A0A1W2PR17|A0A1W2PR17_HUMAN,tr|Q5W015|Q5W015_HUMAN,tr|F2Z2I2|F2Z2I2_HUMAN,tr|H0Y483|H0Y483_HUMAN,tr|Q5VX20|Q5VX20_HUMAN" 6 1088.5826 2.41 45633 11210 2 1088.581948 545.2986 "6-phosphofructo-2-kinase\fructose-2,6-bisphosphatase 3 OS=Homo sapiens OX=9606 GN=PFKFB3 PE=1 SV=1" 5.72 2295 - 960198 - - - -0.5879 - 1.771 0.209 - 181.6 1 2 0 -0.0006 10 0 0 0 2.25E+07 9.34E+06 - - - 2.1798 0.9995 221125_WJC_METTL3_EV_vs_WT_F04.11212.11212.3 3.20E-05 15/40 R.YEALK[136.11]EPMVAR[166.11].K "sp|Q13813|SPTN1_HUMAN,tr|A0A0D9SF54|A0A0D9SF54_HUMAN,tr|A0A0D9SGF6|A0A0D9SGF6_HUMAN" 3 1323.6976 0.31 45634 11212 3 1323.694873 442.2398 "Spectrin alpha chain, non-erythrocytic 1 OS=Homo sapiens OX=9606 GN=SPTAN1 PE=1 SV=3" 6.14 2295.2 - 598856 - - - -2.0435 - 2.306 0.435 - 237 1 2 1 -0.0027 11 0 0 0 8.29E+06 2.68E+07 - - - 5.7626 0.996 221125_WJC_METTL3_EV_vs_WT_F04.11214.11214.2 0.119 16-Sep K.DSLSDDVVK[136.11].A sp|Q6YN16|HSDL2_HUMAN 1 984.4855 0.52 45635 11214 2 984.482845 493.25 Hydroxysteroid dehydrogenase-like protein 2 OS=Homo sapiens OX=9606 GN=HSDL2 PE=1 SV=1 3.93 2295.4 - 3.52E+06 - - - -2.7029 - 1.633 0.246 - 149.5 1 2 0 -0.0027 9 0 0 0 4.38E+07 8.41E+07 - - - 2.2759 1 221125_WJC_METTL3_EV_vs_WT_F04.11215.11215.2 1.01E-05 13/20 R.C[160.03]TEDMTEDELR.E "sp|Q13148|TADBP_HUMAN,tr|A0A087WX67|A0A087WX67_HUMAN,tr|G3V162|G3V162_HUMAN,tr|A0A087WV68|A0A087WV68_HUMAN,tr|A0A087WXV3|A0A087WXV3_HUMAN,tr|A0A087WYY0|A0A087WYY0_HUMAN,tr|A0A087WZM1|A0A087WZM1_HUMAN,tr|K7EN94|K7EN94_HUMAN,tr|A0A0A0N0M3|A0A0A0N0M3_HUMAN,tr|A0A087WW61|A0A087WW61_HUMAN,tr|B1AKP7|B1AKP7_HUMAN,tr|A0A087WZC9|A0A087WZC9_HUMAN,tr|A0A087WXQ5|A0A087WXQ5_HUMAN,tr|A0A087X260|A0A087X260_HUMAN" 14 1397.5439 1.91 45636 11215 2 1397.541431 699.7792 TAR DNA-binding protein 43 OS=Homo sapiens OX=9606 GN=TARDBP PE=1 SV=1 3.83 2295.6 - 609444 - - - -1.7631 - 2.787 0.637 - 822.1 1 2 0 -0.0025 11 0 0 0 2.12E+07 1.11E+07 - - - 6.5179 0.9995 221125_WJC_METTL3_EV_vs_WT_F04.11219.11219.3 0.0867 13/40 K.LTPLSHEVISR[166.11].Q "sp|Q2VIR3|IF2GL_HUMAN,sp|P41091|IF2G_HUMAN,tr|H7BZU1|H7BZU1_HUMAN" 3 1260.7066 13.09 45638 11219 3 1260.703774 421.2428 Eukaryotic translation initiation factor 2 subunit 3B OS=Homo sapiens OX=9606 GN=EIF2S3B PE=2 SV=2 6.75 2296.1 - 4.20E+06 - - - -2.2067 - 2.207 0.325 - 270.5 1 2 0 -0.0028 11 0 0 0 2.08E+09 1.59E+08 - - - 4.4116 0.9999 221125_WJC_METTL3_EV_vs_WT_F04.11221.11221.3 0.000686 15/44 K.LASASLLDTDKR.Y "sp|Q9NY61|AATF_HUMAN,tr|A0A7P0T868|A0A7P0T868_HUMAN,tr|A0A7P0TAR0|A0A7P0TAR0_HUMAN,tr|A0A7P0TBG4|A0A7P0TBG4_HUMAN,tr|A0A7P0Z4N2|A0A7P0Z4N2_HUMAN,tr|A0A087WTH8|A0A087WTH8_HUMAN,tr|A0A7P0Z434|A0A7P0Z434_HUMAN" 7 1288.6987 1.85 45640 11221 3 1288.697424 430.5735 Protein AATF OS=Homo sapiens OX=9606 GN=AATF PE=1 SV=1 5.96 2296.4 - 1.22E+06 - - - -0.9746 - 2.526 0.361 - 164.9 1 2 0 -0.0013 12 0 0 0 2.62E+07 1.42E+07 - - - 5.1329 0.9839 221125_WJC_METTL3_EV_vs_WT_F04.11227.11227.2 0.000826 16-Dec T.PLSHEVISR.Q "sp|Q2VIR3|IF2GL_HUMAN,sp|P41091|IF2G_HUMAN,tr|H7BZU1|H7BZU1_HUMAN" 3 1036.5665 0.66 45643 11227 2 1036.565773 519.2905 Eukaryotic translation initiation factor 2 subunit 3B OS=Homo sapiens OX=9606 GN=EIF2S3B PE=2 SV=2 7.18 2297.2 - 2.00E+06 - - - -0.7428 - 1.742 0.426 - 417.9 1 1 0 -0.0008 9 0 0 0 1.64E+07 2.47E+07 - - - 3.7929 0.9767 221125_WJC_METTL3_EV_vs_WT_F04.11229.11229.2 0.00408 16-Sep Y.EELQITAGR.H "sp|P04264|K2C1_HUMAN,sp|P04259|K2C6B_HUMAN" 2 1015.5298 89.12 45644 11229 2 1015.528848 508.7722 "Keratin, type II cytoskeletal 1 OS=Homo sapiens OX=9606 GN=KRT1 PE=1 SV=6" 4.53 2297.4 - 938380 - - - -0.9611 - 1.962 0.332 - 314.2 1 1 0 -0.001 9 0 0 0 2.57E+07 2.88E+05 - - - 3.4427 0.9999 221125_WJC_METTL3_EV_vs_WT_F04.11231.11231.3 0.000805 18/48 K.AYLEEEC[160.03]PATLRK.Y "sp|P25311|ZA2G_HUMAN,tr|C9JEV0|C9JEV0_HUMAN" 2 1578.7712 634.74 45645 11231 3 1578.769179 527.2643 Zinc-alpha-2-glycoprotein OS=Homo sapiens OX=9606 GN=AZGP1 PE=1 SV=2 4.79 2297.6 - 2.20E+06 - - - -1.2757 - 2.628 0.418 - 396.2 1 2 0 -0.002 13 0 0 0 3.33E+07 5.25E+04 - - - 5.8194 0.999 221125_WJC_METTL3_EV_vs_WT_F04.11232.11232.2 0.0438 14-Sep K.QLIVGVNK[136.11].M "sp|Q05639|EF1A2_HUMAN,sp|P68104|EF1A1_HUMAN,sp|Q5VTE0|EF1A3_HUMAN,sp|P06276|CHLE_HUMAN,tr|A0A2R8Y488|A0A2R8Y488_HUMAN,tr|A0A7I2V659|A0A7I2V659_HUMAN,tr|A0A7I2V3H3|A0A7I2V3H3_HUMAN,tr|F8WF14|F8WF14_HUMAN,tr|A0A2U3TZH3|A0A2U3TZH3_HUMAN,tr|A0A7I2V5N4|A0A7I2V5N4_HUMAN,tr|A0A087WVQ9|A0A087WVQ9_HUMAN,tr|A0A087WV01|A0A087WV01_HUMAN,tr|F8WEX7|F8WEX7_HUMAN" 13 877.5477 0.3 45646 11232 2 877.546721 439.7811 Elongation factor 1-alpha 2 OS=Homo sapiens OX=9606 GN=EEF1A2 PE=1 SV=1 8.75 2297.7 - 1.29E+06 - - - -1.0609 - 1.378 0.342 - 254.8 1 2 0 -0.0009 8 0 0 0 8.44E+06 2.78E+07 - - - 2.5337 0.9746 221125_WJC_METTL3_EV_vs_WT_F04.11233.11233.2 0.0211 12-Aug V.NQQEFVR[166.11].A "sp|P39019|RS19_HUMAN,tr|M0R140|M0R140_HUMAN,tr|M0R2L9|M0R2L9_HUMAN,tr|M0QYF7|M0QYF7_HUMAN" 4 929.4594 1.26 45647 11233 2 929.458759 465.737 40S ribosomal protein S19 OS=Homo sapiens OX=9606 GN=RPS19 PE=1 SV=2 6 2297.9 - 1.11E+06 - - - -0.7424 - 1.61 0.367 - 470.6 1 1 0 -0.0007 7 0 0 0 2.94E+07 2.33E+07 - - - 3.2604 0.9985 221125_WJC_METTL3_EV_vs_WT_F04.11235.11235.2 0.00375 18-Jun K.YWQSNMNNVK.M "sp|Q9C0J8|WDR33_HUMAN,tr|C9J8B4|C9J8B4_HUMAN" 2 1282.5765 999 45649 11235 2 1282.576192 642.2955 pre-mRNA 3' end processing protein WDR33 OS=Homo sapiens OX=9606 GN=WDR33 PE=1 SV=2 8.59 2298.1 - 322482 - - - -0.2058 - 1.111 0.36 - 68.6 1 2 0 -0.0003 10 0 0 0 8.81E+06 0.00E+00 - - - 1.9937 0.999 221125_WJC_METTL3_EV_vs_WT_F04.11238.11238.3 0.0788 Oct-32 K.YAELLEEHR[166.11].N sp|P40222|TXLNA_HUMAN 1 1168.5752 1.24 45650 11238 3 1168.572771 390.5323 Alpha-taxilin OS=Homo sapiens OX=9606 GN=TXLNA PE=1 SV=3 4.75 2298.5 - 1.18E+06 - - - -2.0846 - 2.075 0.271 - 132.2 1 2 0 -0.0024 9 0 0 0 2.58E+07 2.09E+07 - - - 3.7607 0.9995 221125_WJC_METTL3_EV_vs_WT_F04.11239.11239.2 0.0071 16-Aug K.NFGDQPDIR[166.11].C sp|Q15393|SF3B3_HUMAN 1 1070.502 0.65 45651 11239 2 1070.500974 536.2583 Splicing factor 3B subunit 3 OS=Homo sapiens OX=9606 GN=SF3B3 PE=1 SV=4 4.21 2298.6 - 322966 - - - -0.9977 - 1.36 0.443 - 206.7 1 2 0 -0.0011 9 0 0 0 7.94E+06 1.23E+07 - - - 3.2022 0.9939 221125_WJC_METTL3_EV_vs_WT_F04.11242.11242.2 5.27E-05 18-Oct K.AEPVEVVAPR.G "sp|P09874|PARP1_HUMAN,tr|A0A7I2V3E1|A0A7I2V3E1_HUMAN" 2 1065.5819 2.78 45652 11242 2 1065.575965 533.7982 Poly [ADP-ribose] polymerase 1 OS=Homo sapiens OX=9606 GN=PARP1 PE=1 SV=4 4.53 2299 - 491621 - - - -5.5313 - 1.848 0.435 - 333.8 1 2 0 -0.0059 10 0 0 0 9.10E+06 3.28E+06 - - - 3.9662 0.9996 221125_WJC_METTL3_EV_vs_WT_F04.11248.11248.2 0.00732 16-Nov R.NSLDSFGGR[166.11].N sp|Q5BKZ1|ZN326_HUMAN 1 961.4493 1.27 45656 11248 2 961.450022 481.7319 DBIRD complex subunit ZNF326 OS=Homo sapiens OX=9606 GN=ZNF326 PE=1 SV=2 5.84 2299.8 - 975402 - - - 0.7728 - 1.988 0.348 - 371 1 2 0 0.0007 9 0 0 0 4.03E+07 3.18E+07 - - - 3.599 0.999 221125_WJC_METTL3_EV_vs_WT_F04.11249.11249.2 0.125 14-Aug R.INVELSTK[136.11].G sp|Q96PK6|RBM14_HUMAN 1 910.5215 1.8 45657 11249 2 910.520394 456.268 RNA-binding protein 14 OS=Homo sapiens OX=9606 GN=RBM14 PE=1 SV=2 6 2299.9 - 776905 - - - -1.2114 - 1.507 0.319 - 177.6 1 2 0 -0.0011 8 0 0 0 2.67E+07 1.48E+07 - - - 2.6337 0.9999 221125_WJC_METTL3_EV_vs_WT_F04.11252.11252.2 0.00015 20-Dec R.C[160.03]TEDMTEDELR[166.11].E "sp|Q13148|TADBP_HUMAN,tr|A0A087WX67|A0A087WX67_HUMAN,tr|G3V162|G3V162_HUMAN,tr|A0A087WV68|A0A087WV68_HUMAN,tr|A0A087WXV3|A0A087WXV3_HUMAN,tr|A0A087WYY0|A0A087WYY0_HUMAN,tr|A0A087WZM1|A0A087WZM1_HUMAN,tr|K7EN94|K7EN94_HUMAN,tr|A0A0A0N0M3|A0A0A0N0M3_HUMAN,tr|A0A087WW61|A0A087WW61_HUMAN,tr|B1AKP7|B1AKP7_HUMAN,tr|A0A087WZC9|A0A087WZC9_HUMAN,tr|A0A087WXQ5|A0A087WXQ5_HUMAN,tr|A0A087X260|A0A087X260_HUMAN" 14 1407.5522 1.91 45660 11252 2 1407.552899 704.7834 TAR DNA-binding protein 43 OS=Homo sapiens OX=9606 GN=TARDBP PE=1 SV=1 3.83 2300.3 - 407482 - - - 0.5215 - 2.253 0.537 - 449 1 2 0 0.0007 11 0 0 0 2.12E+07 1.11E+07 - - - 5.2044 0.9997 221125_WJC_METTL3_EV_vs_WT_F04.11255.11255.2 0.0999 16-Oct R.NSLDSFGGR.N sp|Q5BKZ1|ZN326_HUMAN 1 951.441 1.27 45662 11255 2 951.440253 476.7278 DBIRD complex subunit ZNF326 OS=Homo sapiens OX=9606 GN=ZNF326 PE=1 SV=2 5.84 2300.8 - 1.77E+06 - - - -0.7946 - 2.141 0.333 - 429.5 1 2 0 -0.0008 9 0 0 0 4.03E+07 3.18E+07 - - - 3.7027 0.9988 221125_WJC_METTL3_EV_vs_WT_F04.11256.11256.2 0.238 14-Aug R.INVELSTK.G sp|Q96PK6|RBM14_HUMAN 1 902.5073 1.84 45663 11256 2 902.506072 452.2609 RNA-binding protein 14 OS=Homo sapiens OX=9606 GN=RBM14 PE=1 SV=2 6 2300.9 - 1.73E+06 - - - -1.3573 - 1.693 0.259 - 148.6 1 2 0 -0.0012 8 0 0 0 2.74E+07 1.49E+07 - - - 2.5415 0.9998 221125_WJC_METTL3_EV_vs_WT_F04.11257.11257.3 0.0018 Dec-36 R.DLYDDK[136.11]DGLR[166.11].K sp|Q12874|SF3A3_HUMAN 1 1226.5898 4.03 45664 11257 3 1226.587953 409.8705 Splicing factor 3A subunit 3 OS=Homo sapiens OX=9606 GN=SF3A3 PE=1 SV=1 4.14 2301 - 1.21E+06 - - - -1.5066 - 2.264 0.485 - 246.7 1 2 1 -0.0018 10 0 0 0 1.12E+08 2.79E+07 - - - 6.3331 1 221125_WJC_METTL3_EV_vs_WT_F04.11258.11258.2 6.00E-08 24-Dec R.VLIGGDETPEGQR.A sp|O60701|UGDH_HUMAN 1 1369.6838 1.25 45665 11258 2 1369.682819 685.8492 UDP-glucose 6-dehydrogenase OS=Homo sapiens OX=9606 GN=UGDH PE=1 SV=1 4.14 2301.1 - 945919 - - - -0.6856 - 2.549 0.6 - 485.7 1 2 0 -0.0009 13 0 0 0 1.47E+07 1.18E+07 - - - 5.8738 0.9991 221125_WJC_METTL3_EV_vs_WT_F04.11260.11260.2 0.00783 20-Nov R.VGSGSLDNLGR[166.11].F "sp|Q13136|LIPA1_HUMAN,tr|H0YDW2|H0YDW2_HUMAN,tr|A0A2R8Y7R9|A0A2R8Y7R9_HUMAN" 3 1083.5548 0.56 45667 11260 2 1083.551326 542.7847 Liprin-alpha-1 OS=Homo sapiens OX=9606 GN=PPFIA1 PE=1 SV=1 5.81 2301.4 - 372746 - - - -3.2117 - 2.053 0.458 - 301 1 2 0 -0.0035 11 0 0 0 2.37E+06 4.23E+06 - - - 4.3686 0.9999 221125_WJC_METTL3_EV_vs_WT_F04.11262.11262.2 6.96E-05 20-Nov R.TEEGPTLSYGR[166.11].D "sp|P43243|MATR3_HUMAN,tr|A8MXP9|A8MXP9_HUMAN,tr|D6R991|D6R991_HUMAN,tr|A0A0R4J2E8|A0A0R4J2E8_HUMAN,tr|D6REM6|D6REM6_HUMAN" 5 1218.5756 1.35 45668 11262 2 1218.574804 610.2951 Matrin-3 OS=Homo sapiens OX=9606 GN=MATR3 PE=1 SV=2 4.53 2301.6 - 4.79E+06 - - - -0.654 - 2.328 0.529 - 517.4 1 2 0 -0.0008 11 0 0 0 6.46E+09 4.79E+09 - - - 5.2339 0.9987 221125_WJC_METTL3_EV_vs_WT_F04.11263.11263.2 0.0076 20-Sep K.IGSTIDDTISK.F sp|Q14677|EPN4_HUMAN 1 1148.5925 1.13 45669 11263 2 1148.59371 575.3035 Clathrin interactor 1 OS=Homo sapiens OX=9606 GN=CLINT1 PE=1 SV=1 4.21 2301.6 - 2.16E+06 - - - 1.0674 - 1.622 0.279 - 182.5 1 2 0 0.0012 11 0 0 0 5.16E+08 4.54E+08 - - - 2.4097 0.9982 221125_WJC_METTL3_EV_vs_WT_F04.11265.11265.3 0.356 Aug-36 R.LKYENEVALR.Q "sp|P13645|K1C10_HUMAN,tr|A0A1B0GVI3|A0A1B0GVI3_HUMAN" 2 1233.6717 0.05 45671 11265 3 1233.671364 412.2312 "Keratin, type I cytoskeletal 10 OS=Homo sapiens OX=9606 GN=KRT10 PE=1 SV=6" 6.14 2301.8 - 938593 - - - -0.3023 - 1.833 0.333 - 77 1 2 1 -0.0004 10 0 0 0 3.19E+07 6.86E+08 - - - 4.0222 0.9994 221125_WJC_METTL3_EV_vs_WT_F04.11267.11267.2 0.00102 18-Oct R.GEALSALDSK.A sp|O75396|SC22B_HUMAN 1 989.5029 1.2 45673 11267 2 989.503147 495.7587 Vesicle-trafficking protein SEC22b OS=Homo sapiens OX=9606 GN=SEC22B PE=1 SV=5 4.37 2302.1 - 773220 - - - 0.2092 - 2.158 0.223 - 478.3 1 2 0 0.0002 10 0 0 0 7.40E+06 6.16E+06 - - - 2.835 0.99 221125_WJC_METTL3_EV_vs_WT_F04.11268.11268.3 0.000927 Dec-44 R.YLAEFATGNDR[166.11]K[136.11].E "sp|P62258|1433E_HUMAN,tr|K7EM20|K7EM20_HUMAN" 2 1401.7007 1.83 45674 11268 3 1401.69835 468.2409 14-3-3 protein epsilon OS=Homo sapiens OX=9606 GN=YWHAE PE=1 SV=1 6.07 2302.2 - 562546 - - - -1.7115 - 1.839 0.163 - 121.4 1 2 0 -0.0024 12 0 0 0 1.60E+07 8.76E+06 - - - 2.0453 0.9974 221125_WJC_METTL3_EV_vs_WT_F04.11269.11269.2 0.0307 16-Aug K.ENGITQALR[166.11].V "sp|Q5T3I0|GPTC4_HUMAN,tr|E9PPY4|E9PPY4_HUMAN,tr|F2Z3C6|F2Z3C6_HUMAN,tr|F8W895|F8W895_HUMAN,tr|A0A0A0MRK1|A0A0A0MRK1_HUMAN,tr|E9PAV9|E9PAV9_HUMAN" 6 1010.5384 1.55 45675 11269 2 1010.539216 506.2765 G patch domain-containing protein 4 OS=Homo sapiens OX=9606 GN=GPATCH4 PE=1 SV=2 6.1 2302.3 - 550439 - - - 0.7798 - 1.559 0.191 - 228.3 1 2 0 0.0008 9 0 0 0 1.10E+07 7.10E+06 - - - 1.7361 0.9996 221125_WJC_METTL3_EV_vs_WT_F04.11270.11270.2 0.000862 20-Jul R.VNEFGESYEEK.A "sp|Q96KA5|CLP1L_HUMAN,tr|G5E9Z2|G5E9Z2_HUMAN" 2 1329.5725 0.27 45676 11270 2 1329.571825 665.7935 Cleft lip and palate transmembrane protein 1-like protein OS=Homo sapiens OX=9606 GN=CLPTM1L PE=1 SV=1 4.09 2302.5 - 182463 - - - -0.4896 - 1.466 0.451 - 132.9 1 2 0 -0.0007 11 0 0 0 1.51E+06 5.60E+06 - - - 3.4067 0.999 221125_WJC_METTL3_EV_vs_WT_F04.11274.11274.2 0.00338 20-Sep K.QLQAETEPIVK[136.11].M "sp|P60228|EIF3E_HUMAN,tr|A0A7I2V3I2|A0A7I2V3I2_HUMAN,tr|A0A7I2V570|A0A7I2V570_HUMAN,tr|A0A7I2V2Q9|A0A7I2V2Q9_HUMAN,tr|H0YBP5|H0YBP5_HUMAN,tr|A0A7I2V5Z6|A0A7I2V5Z6_HUMAN,tr|A0A7I2V2H9|A0A7I2V2H9_HUMAN,tr|B3KW56|B3KW56_HUMAN,tr|A0A7I2V4B4|A0A7I2V4B4_HUMAN,tr|A0A7I2V3I0|A0A7I2V3I0_HUMAN,tr|A0A7I2V3S3|A0A7I2V3S3_HUMAN,tr|A0A7I2V4G3|A0A7I2V4G3_HUMAN,tr|A0A7I2V3W9|A0A7I2V3W9_HUMAN,tr|H0YBR5|H0YBR5_HUMAN,tr|A0A7I2V429|A0A7I2V429_HUMAN,tr|A0A7I2V2W0|A0A7I2V2W0_HUMAN,tr|A0A161SXE1|A0A161SXE1_HUMAN" 17 1262.6962 0.39 45678 11274 2 1262.698808 632.3554 Eukaryotic translation initiation factor 3 subunit E OS=Homo sapiens OX=9606 GN=EIF3E PE=1 SV=1 4.53 2302.9 - 1.12E+06 - - - 2.0916 - 1.846 0.341 - 340.2 1 2 0 0.0026 11 0 0 0 8.13E+06 2.10E+07 - - - 3.2172 0.9999 221125_WJC_METTL3_EV_vs_WT_F04.11276.11276.2 0.000474 18-Sep R.SLVDYENANK[136.11].A "sp|Q9UNH7|SNX6_HUMAN,tr|A0A0A0MRI2|A0A0A0MRI2_HUMAN" 2 1159.5601 1.42 45680 11276 2 1159.560125 580.7873 Sorting nexin-6 OS=Homo sapiens OX=9606 GN=SNX6 PE=1 SV=1 4.37 2303.1 - 1.18E+06 - - - 0.0492 - 1.842 0.516 - 178.9 1 2 0 0.0001 10 0 0 0 1.88E+07 1.33E+07 - - - 4.5572 0.9684 221125_WJC_METTL3_EV_vs_WT_F04.11277.11277.2 0.0599 14-Oct V.PQQIEVAR.Q sp|Q96I24|FUBP3_HUMAN 1 939.5138 1.54 45681 11277 2 939.514243 470.7642 Far upstream element-binding protein 3 OS=Homo sapiens OX=9606 GN=FUBP3 PE=1 SV=2 6.43 2303.2 - 1.01E+06 - - - 0.4928 - 1.963 0.264 - 405 1 1 0 0.0005 8 0 0 0 2.32E+07 1.51E+07 - - - 3.0249 0.9992 221125_WJC_METTL3_EV_vs_WT_F04.11279.11279.2 0.0564 16-Aug K.TTLTAAITK[136.11].L "sp|P49411|EFTU_HUMAN,tr|H3BNU3|H3BNU3_HUMAN" 2 926.5528 3.91 45683 11279 2 926.552954 464.2837 "Elongation factor Tu, mitochondrial OS=Homo sapiens OX=9606 GN=TUFM PE=1 SV=2" 8.41 2303.5 - 403603 - - - 0.1694 - 1.717 0.264 - 162.6 1 2 0 0.0002 9 0 0 0 1.14E+07 2.91E+06 - - - 2.5548 0.9989 221125_WJC_METTL3_EV_vs_WT_F04.11281.11281.2 4 24-Oct R.ALAAVPSAGSVQR[166.11].V "sp|Q14160|SCRIB_HUMAN,tr|A0A669KB89|A0A669KB89_HUMAN,tr|A0A0G2JPP5|A0A0G2JPP5_HUMAN,tr|A0A0G2JNZ2|A0A0G2JNZ2_HUMAN,tr|A0A0G2JMS7|A0A0G2JMS7_HUMAN,tr|H0YCG0|H0YCG0_HUMAN" 6 1235.6862 0.72 45685 11281 2 1235.685563 618.8504 Protein scribble homolog OS=Homo sapiens OX=9606 GN=SCRIB PE=1 SV=4 9.79 2303.7 - 362177 - - - -0.4791 - 1.876 0.228 - 284.7 1 2 0 -0.0006 13 0 0 0 3.09E+06 4.27E+06 - - - 2.3395 0.9997 221125_WJC_METTL3_EV_vs_WT_F04.11283.11283.2 0.000558 20-Oct R.VGSGSLDNLGR.F "sp|Q13136|LIPA1_HUMAN,tr|H0YDW2|H0YDW2_HUMAN,tr|A0A2R8Y7R9|A0A2R8Y7R9_HUMAN" 3 1073.5465 0.54 45687 11283 2 1073.548206 537.7805 Liprin-alpha-1 OS=Homo sapiens OX=9606 GN=PPFIA1 PE=1 SV=1 5.81 2304 - 324941 - - - 1.5556 - 2.229 0.403 - 291.6 1 2 0 0.0017 11 0 0 0 2.28E+06 4.23E+06 - - - 4.1854 0.999 221125_WJC_METTL3_EV_vs_WT_F04.11285.11285.2 0.000334 20-Aug R.SSGC[160.03]FPNMAAK[136.11].V sp|Q96I24|FUBP3_HUMAN 1 1176.5147 4.38 45689 11285 2 1176.511562 589.2646 Far upstream element-binding protein 3 OS=Homo sapiens OX=9606 GN=FUBP3 PE=1 SV=2 7.94 2304.3 - 427086 - - - -2.6791 - 1.502 0.478 - 161.4 1 2 0 -0.0032 11 0 0 0 1.62E+07 3.70E+06 - - - 3.671 0.9998 221125_WJC_METTL3_EV_vs_WT_F04.11288.11288.3 2.18E-06 28-Nov K.YC[160.03]FVDK[136.11]YK[136.11].G "sp|Q8IY67|RAVR1_HUMAN,tr|K7EKR9|K7EKR9_HUMAN,tr|E9PAU2|E9PAU2_HUMAN,tr|A0A087WZ13|A0A087WZ13_HUMAN" 4 1137.55 0.001 45691 11288 3 1137.549856 380.1906 Ribonucleoprotein PTB-binding 1 OS=Homo sapiens OX=9606 GN=RAVER1 PE=1 SV=1 8.15 2304.6 - 723351 - - - -0.0976 - 1.821 0.488 - 119 1 2 1 -0.0001 8 0 0 0 0.00E+00 1.10E+07 - - - 5.8541 0.9999 221125_WJC_METTL3_EV_vs_WT_F04.11289.11289.3 4.43E-05 15/44 K.GGGHVAQIYAIR[166.11].Q "sp|P62249|RS16_HUMAN,tr|M0R210|M0R210_HUMAN,tr|M0R3H0|M0R3H0_HUMAN,tr|M0QX76|M0QX76_HUMAN,tr|M0R1M5|M0R1M5_HUMAN" 5 1250.6759 0.08 45692 11289 3 1250.678608 417.8993 40S ribosomal protein S16 OS=Homo sapiens OX=9606 GN=RPS16 PE=1 SV=2 8.75 2304.7 - 9.76E+06 - - - 2.1452 - 2.512 0.472 - 429.7 1 2 0 0.0027 12 0 0 0 2.24E+08 2.79E+09 - - - 6.3547 0.9834 221125_WJC_METTL3_EV_vs_WT_F04.11290.11290.2 0.0187 16-Sep R.LASYLDKVR.A "sp|Q04695|K1C17_HUMAN,sp|Q99456|K1C12_HUMAN,sp|P13645|K1C10_HUMAN,sp|P02533|K1C14_HUMAN,sp|P08727|K1C19_HUMAN,sp|P08779|K1C16_HUMAN,sp|P19012|K1C15_HUMAN,tr|K7EPJ9|K7EPJ9_HUMAN,tr|C9JM50|C9JM50_HUMAN,tr|A0A1B0GVI3|A0A1B0GVI3_HUMAN,tr|A0A3B3ITG2|A0A3B3ITG2_HUMAN" 11 1063.6026 999 45693 11290 2 1063.603377 532.8086 "Keratin, type I cytoskeletal 17 OS=Homo sapiens OX=9606 GN=KRT17 PE=1 SV=2" 8.59 2304.7 - 1.36E+06 - - - 0.7352 - 1.791 0.194 - 322.9 1 2 1 0.0008 9 0 0 0 1.05E+07 0.00E+00 - - - 2.1596 0.9998 221125_WJC_METTL3_EV_vs_WT_F04.11291.11291.2 1.00E-05 20-Sep K.ESMQMQVEAER.R "sp|Q9UJZ1|STML2_HUMAN,tr|A0A087WYB4|A0A087WYB4_HUMAN" 2 1336.5751 1.47 45694 11291 2 1336.576062 669.2948 "Stomatin-like protein 2, mitochondrial OS=Homo sapiens OX=9606 GN=STOML2 PE=1 SV=1" 4.25 2304.8 - 1.14E+06 - - - 0.6928 - 2.122 0.471 - 404.5 1 2 0 0.0009 11 0 0 0 1.16E+07 7.88E+06 - - - 4.5548 0.9998 221125_WJC_METTL3_EV_vs_WT_F04.11292.11292.2 0.00763 14/22 R.SLGQNPTEAELR.D sp|P27482|CALL3_HUMAN 1 1313.6575 2.13 45695 11292 2 1313.658726 657.836 Calmodulin-like protein 3 OS=Homo sapiens OX=9606 GN=CALML3 PE=1 SV=2 4.53 2304.9 - 580091 - - - 0.9005 - 2.38 0.451 - 678.2 1 2 0 0.0012 12 0 0 0 1.88E+07 8.85E+06 - - - 4.6532 0.9999 221125_WJC_METTL3_EV_vs_WT_F04.11293.11293.2 4.49E-05 20-Sep R.DNSTMGYMAAK[136.11].K sp|P07900|HS90A_HUMAN 1 1195.5093 0.53 45696 11293 2 1195.510621 598.7619 Heat shock protein HSP 90-alpha OS=Homo sapiens OX=9606 GN=HSP90AA1 PE=1 SV=5 5.83 2305.1 - 571652 - - - 1.11 - 2.111 0.556 - 367.6 1 2 0 0.0013 11 0 0 0 6.38E+06 1.21E+07 - - - 5.1684 0.9996 221125_WJC_METTL3_EV_vs_WT_F04.11294.11294.2 3.33E-06 16-Sep R.NC[160.03]AIISDVK.V sp|Q7LBC6|KDM3B_HUMAN 1 1018.5117 0.28 45697 11294 2 1018.513942 510.2631 Lysine-specific demethylase 3B OS=Homo sapiens OX=9606 GN=KDM3B PE=1 SV=2 5.83 2305.2 - 547290 - - - 2.1708 - 1.911 0.481 - 373.8 1 2 0 0.0022 9 0 0 0 3.80E+06 1.35E+07 - - - 4.4666 1 221125_WJC_METTL3_EV_vs_WT_F04.11296.11296.2 0.000117 13/22 K.TPALANEEALQK.L "sp|Q15390|MTFR1_HUMAN,tr|H0YBZ4|H0YBZ4_HUMAN" 2 1283.6721 1.54 45699 11296 2 1283.674156 642.8433 Mitochondrial fission regulator 1 OS=Homo sapiens OX=9606 GN=MTFR1 PE=1 SV=2 4.53 2305.5 - 457594 - - - 1.5775 - 2.705 0.561 - 620.1 1 2 0 0.002 12 0 0 0 8.81E+06 5.74E+06 - - - 5.8022 0.9998 221125_WJC_METTL3_EV_vs_WT_F04.11297.11297.2 4.30E-05 22-Nov K.LGSSSEIEVPAK[136.11].T "sp|Q6UXV4|MIC27_HUMAN,tr|A0A087WYF7|A0A087WYF7_HUMAN" 2 1223.6489 1.79 45700 11297 2 1223.650109 612.8317 MICOS complex subunit MIC27 OS=Homo sapiens OX=9606 GN=APOOL PE=1 SV=1 4.53 2305.6 - 395898 - - - 1.0019 - 2.072 0.444 - 366.5 1 2 0 0.0012 12 0 0 0 2.51E+06 1.40E+06 - - - 4.2368 0.9992 221125_WJC_METTL3_EV_vs_WT_F04.11300.11300.2 0.0112 20-Oct R.DNSTMGYMAAK.K sp|P07900|HS90A_HUMAN 1 1187.4951 0.53 45703 11300 2 1187.499035 594.7548 Heat shock protein HSP 90-alpha OS=Homo sapiens OX=9606 GN=HSP90AA1 PE=1 SV=5 5.83 2306 - 259501 - - - 3.3188 - 1.973 0.51 - 332.4 1 2 0 0.0039 11 0 0 0 6.38E+06 1.21E+07 - - - 4.645 0.9992 221125_WJC_METTL3_EV_vs_WT_F04.11305.11305.2 0.00194 16-Aug R.QTVAVGVIK[136.11].N "sp|Q05639|EF1A2_HUMAN,sp|P68104|EF1A1_HUMAN,sp|Q5VTE0|EF1A3_HUMAN,tr|A0A7I2V659|A0A7I2V659_HUMAN,tr|A0A2U3TZH3|A0A2U3TZH3_HUMAN,tr|A0A087WVQ9|A0A087WVQ9_HUMAN" 6 921.5739 0.44 45707 11305 2 921.574679 461.7942 Elongation factor 1-alpha 2 OS=Homo sapiens OX=9606 GN=EEF1A2 PE=1 SV=1 8.75 2306.5 - 1.18E+06 - - - 0.8811 - 1.561 0.338 - 210.2 1 2 0 0.0008 9 0 0 0 9.53E+06 2.15E+07 - - - 2.8256 1 221125_WJC_METTL3_EV_vs_WT_F04.11307.11307.2 4.48E-10 13/22 K.GGGHVAQIYAIR[166.11].Q "sp|P62249|RS16_HUMAN,tr|M0R210|M0R210_HUMAN,tr|M0R3H0|M0R3H0_HUMAN,tr|M0QX76|M0QX76_HUMAN,tr|M0R1M5|M0R1M5_HUMAN" 5 1250.6759 0.87 45709 11307 2 1250.678494 626.3452 40S ribosomal protein S16 OS=Homo sapiens OX=9606 GN=RPS16 PE=1 SV=2 8.75 2306.7 - 1.11E+06 - - - 2.0541 - 2.446 0.623 - 660.4 1 2 0 0.0026 12 0 0 0 7.19E+06 8.23E+06 - - - 5.9951 0.9336 221125_WJC_METTL3_EV_vs_WT_F04.11308.11308.3 0.0196 Dec-36 K.LK[136.11]ELQAIAER[166.11].L "sp|Q13303|KCAB2_HUMAN,tr|A0A590UJJ4|A0A590UJJ4_HUMAN,tr|A0A5F9UN28|A0A5F9UN28_HUMAN,tr|A0A590UJB6|A0A590UJB6_HUMAN" 4 1187.6993 1.84 45710 11308 3 1187.700962 396.907 Voltage-gated potassium channel subunit beta-2 OS=Homo sapiens OX=9606 GN=KCNAB2 PE=1 SV=2 6.14 2306.8 - 949691 - - - 1.4061 - 2.257 0.086 - 161.8 2 2 1 0.0017 10 0 0 0 1.14E+07 6.17E+06 - - - 1.7364 0.9999 221125_WJC_METTL3_EV_vs_WT_F04.11309.11309.2 2.11E-08 24-Nov R.IIYGGSVTGATC[160.03]K.E sp|P60174|TPIS_HUMAN 1 1325.6649 0.93 45711 11309 2 1325.666195 663.8397 Triosephosphate isomerase OS=Homo sapiens OX=9606 GN=TPI1 PE=1 SV=4 8.2 2307 - 652198 - - - 0.949 - 2.392 0.591 - 295 1 2 0 0.0013 13 0 0 0 9.84E+06 1.06E+07 - - - 5.6441 0.9998 221125_WJC_METTL3_EV_vs_WT_F04.11310.11310.2 0.000556 22-Oct K.ATTADGSSILDR[166.11].A "sp|Q9BT78|CSN4_HUMAN,tr|D6RD63|D6RD63_HUMAN,tr|D6RAX7|D6RAX7_HUMAN" 3 1215.5971 1.5 45712 11310 2 1215.597906 608.8058 COP9 signalosome complex subunit 4 OS=Homo sapiens OX=9606 GN=COPS4 PE=1 SV=1 4.21 2307.1 - 633334 - - - 0.6918 - 1.883 0.466 - 409.5 1 2 0 0.0008 12 0 0 0 6.07E+06 4.03E+06 - - - 4.1478 0.9998 221125_WJC_METTL3_EV_vs_WT_F04.11312.11312.2 0.00135 14/22 K.ALLDASETTSTR[166.11].K "sp|Q14258|TRI25_HUMAN,tr|A0A3B3IUA7|A0A3B3IUA7_HUMAN" 2 1273.6389 1.86 45714 11312 2 1273.638203 637.8267 E3 ubiquitin\ISG15 ligase TRIM25 OS=Homo sapiens OX=9606 GN=TRIM25 PE=1 SV=2 4.37 2307.3 - 524147 - - - -0.5708 - 2.532 0.369 - 763.2 1 2 0 -0.0007 12 0 0 0 7.63E+06 4.10E+06 - - - 4.2106 1 221125_WJC_METTL3_EV_vs_WT_F04.11314.11314.3 7.16E-07 13/40 R.MVHIDEEMGPK.T "sp|Q9H2P0|ADNP_HUMAN,tr|A0A2R8Y6X0|A0A2R8Y6X0_HUMAN,tr|A0A669KBJ7|A0A669KBJ7_HUMAN" 3 1284.5842 1.22 45716 11314 3 1284.586457 429.202 Activity-dependent neuroprotector homeobox protein OS=Homo sapiens OX=9606 GN=ADNP PE=1 SV=1 4.65 2307.6 - 486878 - - - 1.7227 - 2.532 0.544 - 254.6 1 2 0 0.0022 11 0 0 0 2.71E+06 2.23E+06 - - - 7.2436 1 221125_WJC_METTL3_EV_vs_WT_F04.11315.11315.2 2.21E-08 15/24 K.LNGQQAALASQYR[166.11].A "sp|Q9Y520|PRC2C_HUMAN,tr|E7EPN9|E7EPN9_HUMAN" 2 1428.7349 1.13 45717 11315 2 1428.738154 715.3747 Protein PRRC2C OS=Homo sapiens OX=9606 GN=PRRC2C PE=1 SV=4 8.75 2307.7 - 316723 - - - 2.2803 - 3.219 0.599 - 1047.5 1 2 0 0.0033 13 0 0 0 9.05E+06 7.99E+06 - - - 6.4646 1 221125_WJC_METTL3_EV_vs_WT_F04.11316.11316.2 5.50E-08 13/24 K.LNGQQAALASQYR.A "sp|Q9Y520|PRC2C_HUMAN,tr|E7EPN9|E7EPN9_HUMAN" 2 1418.7266 1.13 45718 11316 2 1418.726754 710.3706 Protein PRRC2C OS=Homo sapiens OX=9606 GN=PRRC2C PE=1 SV=4 8.75 2307.9 - 285099 - - - 0.0902 - 2.819 0.594 - 710.2 1 2 0 0.0001 13 0 0 0 9.05E+06 7.99E+06 - - - 6.0881 1 221125_WJC_METTL3_EV_vs_WT_F04.11317.11317.2 4.87E-07 24-Oct R.VTPASETLEDPC[160.03]R.T "sp|Q9Y6A5|TACC3_HUMAN,tr|A0A494BZT8|A0A494BZT8_HUMAN,tr|C9JA91|C9JA91_HUMAN,tr|E7EMT0|E7EMT0_HUMAN" 4 1473.677 -1 45719 11317 2 1473.680083 737.8458 Transforming acidic coiled-coil-containing protein 3 OS=Homo sapiens OX=9606 GN=TACC3 PE=1 SV=1 4.14 2308 - 259458 - - - 2.1199 - 2.269 0.645 - 313.8 1 2 0 0.0031 13 0 0 0 0.00E+00 0.00E+00 - - - 5.9068 0.999 221125_WJC_METTL3_EV_vs_WT_F04.11319.11319.2 2.54E-05 24-Aug R.VTPASETLEDPC[160.03]R[166.11].T "sp|Q9Y6A5|TACC3_HUMAN,tr|A0A494BZT8|A0A494BZT8_HUMAN,tr|C9JA91|C9JA91_HUMAN,tr|E7EMT0|E7EMT0_HUMAN" 4 1483.6852 1.4 45721 11319 2 1483.689789 742.8499 Transforming acidic coiled-coil-containing protein 3 OS=Homo sapiens OX=9606 GN=TACC3 PE=1 SV=1 4.14 2308.2 - 215927 - - - 3.0734 - 1.787 0.471 - 165.4 1 2 0 0.0046 13 0 0 0 2.43E+06 1.74E+06 - - - 4.0083 0.9997 221125_WJC_METTL3_EV_vs_WT_F04.11326.11326.2 0.00113 16-Nov K.QHITLALEK.Q "sp|Q16891|MIC60_HUMAN,tr|B9A067|B9A067_HUMAN,tr|C9J406|C9J406_HUMAN,tr|H7C463|H7C463_HUMAN" 4 1051.6026 1.29 45726 11326 2 1051.603692 526.8086 MICOS complex subunit MIC60 OS=Homo sapiens OX=9606 GN=IMMT PE=1 SV=1 6.75 2309 - 2.81E+06 - - - 1.0432 - 1.902 0.41 - 452.9 1 2 0 0.0011 9 0 0 0 2.54E+07 1.96E+07 - - - 3.9289 0.9993 221125_WJC_METTL3_EV_vs_WT_F04.11327.11327.2 0.0368 16-Sep K.QHITLALEK[136.11].Q "sp|Q16891|MIC60_HUMAN,tr|B9A067|B9A067_HUMAN,tr|C9J406|C9J406_HUMAN,tr|H7C463|H7C463_HUMAN" 4 1059.6168 1.29 45727 11327 2 1059.61825 530.8157 MICOS complex subunit MIC60 OS=Homo sapiens OX=9606 GN=IMMT PE=1 SV=1 6.75 2309.1 - 2.65E+06 - - - 1.3731 - 2.011 0.29 - 308.9 1 2 0 0.0015 9 0 0 0 2.54E+07 1.96E+07 - - - 3.2037 0.9999 221125_WJC_METTL3_EV_vs_WT_F04.11330.11330.2 1.67E-05 18-Nov K.EDQTEYLEER[166.11].R "sp|P08238|HS90B_HUMAN,sp|Q58FF6|H90B4_HUMAN,sp|Q58FF7|H90B3_HUMAN,sp|P07900|HS90A_HUMAN,tr|G3V2J8|G3V2J8_HUMAN" 5 1320.5709 0.87 45730 11330 2 1320.571341 661.2927 Heat shock protein HSP 90-beta OS=Homo sapiens OX=9606 GN=HSP90AB1 PE=1 SV=4 3.91 2309.3 - 2.00E+06 - - - 0.3264 - 2.193 0.539 - 678.7 1 2 0 0.0004 10 0 0 0 2.25E+07 2.59E+07 - - - 5.2138 0.9998 221125_WJC_METTL3_EV_vs_WT_F04.11332.11332.2 1.86E-06 20-Dec K.ANSNLVLQADR.S "sp|O75643|U520_HUMAN,tr|A0A494C1A5|A0A494C1A5_HUMAN" 2 1199.6258 2.09 45732 11332 2 1199.623182 600.8202 U5 small nuclear ribonucleoprotein 200 kDa helicase OS=Homo sapiens OX=9606 GN=SNRNP200 PE=1 SV=2 5.88 2309.4 - 1.62E+06 - - - -2.2232 - 2.739 0.523 - 678.8 1 2 0 -0.0027 11 0 0 0 8.67E+07 4.14E+07 - - - 5.6288 0.9992 221125_WJC_METTL3_EV_vs_WT_F04.11334.11334.2 1.27 12-Aug R.K[136.11]LFNLSK[136.11].E "sp|P62753|RS6_HUMAN,tr|A2A3R5|A2A3R5_HUMAN" 2 864.5404 0.99 45734 11334 2 864.541151 433.2775 40S ribosomal protein S6 OS=Homo sapiens OX=9606 GN=RPS6 PE=1 SV=1 10 2309.6 - 1.49E+06 - - - 0.8814 - 1.874 0.234 - 233.9 1 2 0 0.0008 7 0 0 0 1.08E+07 1.09E+07 - - - 2.7592 0.9979 221125_WJC_METTL3_EV_vs_WT_F04.11335.11335.2 0.0078 14-Jun R.DNYSPGWK[136.11].F sp|P07814|SYEP_HUMAN 1 973.4385 0.82 45735 11335 2 973.43983 487.7265 Bifunctional glutamate\proline--tRNA ligase OS=Homo sapiens OX=9606 GN=EPRS1 PE=1 SV=5 5.83 2309.7 - 1.26E+06 - - - 1.3704 - 1.524 0.246 - 159.8 1 2 0 0.0013 8 0 0 0 7.80E+06 9.56E+06 - - - 2.1283 0.9999 221125_WJC_METTL3_EV_vs_WT_F04.11336.11336.2 1.20E-08 24-Oct R.IIYGGSVTGATC[160.03]K[136.11].E sp|P60174|TPIS_HUMAN 1 1333.6791 1.59 45736 11336 2 1333.680632 667.8468 Triosephosphate isomerase OS=Homo sapiens OX=9606 GN=TPI1 PE=1 SV=4 8.2 2309.8 - 1.25E+06 - - - 1.121 - 2.206 0.599 - 210.2 1 2 0 0.0015 13 0 0 0 9.62E+06 6.06E+06 - - - 5.4953 0.9992 221125_WJC_METTL3_EV_vs_WT_F04.11337.11337.2 0.00714 16-Sep R.QTVAVGVIK.N "sp|Q05639|EF1A2_HUMAN,sp|P68104|EF1A1_HUMAN,sp|Q5VTE0|EF1A3_HUMAN,tr|A0A7I2V659|A0A7I2V659_HUMAN,tr|A0A2U3TZH3|A0A2U3TZH3_HUMAN,tr|A0A087WVQ9|A0A087WVQ9_HUMAN" 6 913.5597 0.44 45737 11337 2 913.560394 457.7871 Elongation factor 1-alpha 2 OS=Homo sapiens OX=9606 GN=EEF1A2 PE=1 SV=1 8.75 2309.9 - 1.10E+06 - - - 0.7958 - 1.755 0.281 - 326.8 1 2 0 0.0007 9 0 0 0 9.53E+06 2.15E+07 - - - 2.7435 0.9999 221125_WJC_METTL3_EV_vs_WT_F04.11338.11338.2 1.28E-06 22-Nov R.GGGFGGNDNFGR.G "sp|P09651|ROA1_HUMAN,tr|A0A7I2YQX9|A0A7I2YQX9_HUMAN,tr|A0A7I2V661|A0A7I2V661_HUMAN,tr|A0A7I2V3K5|A0A7I2V3K5_HUMAN,tr|A0A7I2V3R8|A0A7I2V3R8_HUMAN,tr|F8W6I7|F8W6I7_HUMAN,tr|H0YH80|H0YH80_HUMAN,tr|A0A7I2V2L6|A0A7I2V2L6_HUMAN,tr|A0A7I2V3W0|A0A7I2V3W0_HUMAN,tr|A0A7I2V2R4|A0A7I2V2R4_HUMAN,tr|A0A2R8Y4L2|A0A2R8Y4L2_HUMAN,tr|A0A7I2V5L7|A0A7I2V5L7_HUMAN,tr|A0A7I2V453|A0A7I2V453_HUMAN" 13 1153.4901 2.11 45738 11338 2 1153.491302 577.7523 Heterogeneous nuclear ribonucleoprotein A1 OS=Homo sapiens OX=9606 GN=HNRNPA1 PE=1 SV=5 5.84 2310 - 1.09E+06 - - - 1.0559 - 2.066 0.604 - 281.8 1 2 0 0.0012 12 0 0 0 1.40E+07 6.66E+06 - - - 5.411 0.9999 221125_WJC_METTL3_EV_vs_WT_F04.11339.11339.2 0.000569 20-Dec K.ANSNLVLQADR[166.11].S "sp|O75643|U520_HUMAN,tr|A0A494C1A5|A0A494C1A5_HUMAN" 2 1209.6341 2.09 45739 11339 2 1209.635036 605.8243 U5 small nuclear ribonucleoprotein 200 kDa helicase OS=Homo sapiens OX=9606 GN=SNRNP200 PE=1 SV=2 5.88 2310.1 - 888547 - - - 0.7581 - 2.715 0.439 - 685 1 2 0 0.0009 11 0 0 0 8.67E+07 4.14E+07 - - - 4.9851 0.9999 221125_WJC_METTL3_EV_vs_WT_F04.11340.11340.2 3.26E-05 14/22 K.TPALANEEALQK[136.11].L "sp|Q15390|MTFR1_HUMAN,tr|H0YBZ4|H0YBZ4_HUMAN" 2 1291.6863 1.65 45740 11340 2 1291.68779 646.8504 Mitochondrial fission regulator 1 OS=Homo sapiens OX=9606 GN=MTFR1 PE=1 SV=2 4.53 2310.2 - 821128 - - - 1.1295 - 2.773 0.467 - 807 1 2 0 0.0015 12 0 0 0 8.52E+06 5.15E+06 - - - 5.1734 0.9989 221125_WJC_METTL3_EV_vs_WT_F04.11341.11341.2 3.02E-05 14-Aug R.DNYSPGWK.F sp|P07814|SYEP_HUMAN 1 965.4243 0.82 45741 11341 2 965.42748 483.7194 Bifunctional glutamate\proline--tRNA ligase OS=Homo sapiens OX=9606 GN=EPRS1 PE=1 SV=5 5.83 2310.3 - 792630 - - - 3.298 - 1.679 0.474 - 347.4 1 2 0 0.0032 8 0 0 0 7.80E+06 9.56E+06 - - - 4.1038 1 221125_WJC_METTL3_EV_vs_WT_F04.11342.11342.3 0.000138 14/40 K.NFYQEHPDLAR.R "sp|P17844|DDX5_HUMAN,tr|J3QR02|J3QR02_HUMAN,tr|X6RLV5|X6RLV5_HUMAN,tr|A0A7I2V507|A0A7I2V507_HUMAN,tr|J3KTA4|J3KTA4_HUMAN,tr|J3KTQ4|J3KTQ4_HUMAN,tr|A0A7I2V2S0|A0A7I2V2S0_HUMAN,tr|J3QRQ7|J3QRQ7_HUMAN" 8 1388.6473 1.66 45742 11342 3 1388.646925 463.8897 Probable ATP-dependent RNA helicase DDX5 OS=Homo sapiens OX=9606 GN=DDX5 PE=1 SV=1 5.32 2310.4 - 621795 - - - -0.2794 - 2.163 0.471 - 290.9 1 2 0 -0.0004 11 0 0 0 5.46E+08 3.30E+08 - - - 5.9828 0.9999 221125_WJC_METTL3_EV_vs_WT_F04.11343.11343.2 1.03E-05 22-Oct R.GGGFGGNDNFGR[166.11].G "sp|P09651|ROA1_HUMAN,tr|A0A7I2YQX9|A0A7I2YQX9_HUMAN,tr|A0A7I2V661|A0A7I2V661_HUMAN,tr|A0A7I2V3K5|A0A7I2V3K5_HUMAN,tr|A0A7I2V3R8|A0A7I2V3R8_HUMAN,tr|F8W6I7|F8W6I7_HUMAN,tr|H0YH80|H0YH80_HUMAN,tr|A0A7I2V2L6|A0A7I2V2L6_HUMAN,tr|A0A7I2V3W0|A0A7I2V3W0_HUMAN,tr|A0A7I2V2R4|A0A7I2V2R4_HUMAN,tr|A0A2R8Y4L2|A0A2R8Y4L2_HUMAN,tr|A0A7I2V5L7|A0A7I2V5L7_HUMAN,tr|A0A7I2V453|A0A7I2V453_HUMAN" 13 1163.4984 2.14 45743 11343 2 1163.497867 582.7565 Heterogeneous nuclear ribonucleoprotein A1 OS=Homo sapiens OX=9606 GN=HNRNPA1 PE=1 SV=5 5.84 2310.6 - 587429 - - - -0.4186 - 2.043 0.563 - 225.2 1 2 0 -0.0005 12 0 0 0 1.42E+07 6.66E+06 - - - 5.0789 0.9996 221125_WJC_METTL3_EV_vs_WT_F04.11344.11344.2 0.0013 12-Jul R.YTVQFSK.F "sp|Q8IX12|CCAR1_HUMAN,tr|F5H2E6|F5H2E6_HUMAN,tr|F5H1H2|F5H1H2_HUMAN,tr|A0A0C4DGG8|A0A0C4DGG8_HUMAN,tr|F5H3E1|F5H3E1_HUMAN" 5 871.444 2.21 45744 11344 2 871.444183 436.7293 Cell division cycle and apoptosis regulator protein 1 OS=Homo sapiens OX=9606 GN=CCAR1 PE=1 SV=2 8.59 2310.7 - 366297 - - - 0.2456 - 1.438 0.404 - 123.9 1 2 0 0.0002 7 0 0 0 1.45E+07 6.56E+06 - - - 3.1759 0.9919 221125_WJC_METTL3_EV_vs_WT_F04.11347.11347.2 0.0912 18-May R.HPGGGDYEEL.- sp|Q3YEC7|RABL6_HUMAN 1 1072.4462 - 45746 11347 2 1072.446503 537.2304 Rab-like protein 6 OS=Homo sapiens OX=9606 GN=RABL6 PE=1 SV=2 4.13 2311.2 - 281919 - - - 0.3254 - 0.957 0.254 - 71.3 1 2 0 0.0003 10 0 0 0 - - - - - 0.7943 0.9999 221125_WJC_METTL3_EV_vs_WT_F04.11349.11349.3 1.98E-05 15/40 K.NFYQEHPDLAR[166.11].R "sp|P17844|DDX5_HUMAN,tr|J3QR02|J3QR02_HUMAN,tr|X6RLV5|X6RLV5_HUMAN,tr|A0A7I2V507|A0A7I2V507_HUMAN,tr|J3KTA4|J3KTA4_HUMAN,tr|J3KTQ4|J3KTQ4_HUMAN,tr|A0A7I2V2S0|A0A7I2V2S0_HUMAN,tr|J3QRQ7|J3QRQ7_HUMAN" 8 1398.6556 1.66 45748 11349 3 1398.656278 467.2258 Probable ATP-dependent RNA helicase DDX5 OS=Homo sapiens OX=9606 GN=DDX5 PE=1 SV=1 5.32 2311.3 - 2.71E+06 - - - 0.4969 - 2.089 0.435 - 412.4 1 2 0 0.0007 11 0 0 0 5.46E+08 3.30E+08 - - - 5.4824 0.9994 221125_WJC_METTL3_EV_vs_WT_F04.11350.11350.2 0.00207 14-Jul K.VIPELNGK.L "sp|P04406|G3P_HUMAN,tr|E7EUT5|E7EUT5_HUMAN" 2 868.5018 1.06 45749 11350 2 868.502986 435.2582 Glyceraldehyde-3-phosphate dehydrogenase OS=Homo sapiens OX=9606 GN=GAPDH PE=1 SV=3 5.97 2311.3 - 1.78E+06 - - - 1.3448 - 1.415 0.432 - 184.1 1 2 0 0.0012 8 0 0 0 3.78E+07 3.58E+07 - - - 3.2783 0.9994 221125_WJC_METTL3_EV_vs_WT_F04.11351.11351.2 0.00157 20-Sep R.DVQPVAYEEPK[136.11].H "sp|Q99717|SMAD5_HUMAN,tr|H0YAK7|H0YAK7_HUMAN" 2 1281.6332 1.46 45750 11351 2 1281.63421 641.8239 Mothers against decapentaplegic homolog 5 OS=Homo sapiens OX=9606 GN=SMAD5 PE=1 SV=1 4.14 2311.4 - 1.50E+06 - - - 0.7623 - 1.629 0.361 - 236.7 1 2 0 0.001 11 0 0 0 1.72E+07 1.18E+07 - - - 3.0271 0.9998 221125_WJC_METTL3_EV_vs_WT_F04.11352.11352.2 4.06E-05 16-Sep K.IYFTDSSSK.W "sp|Q9HDC9|APMAP_HUMAN,tr|H0Y512|H0Y512_HUMAN" 2 1046.492 1.98 45751 11352 2 1046.491374 524.2533 Adipocyte plasma membrane-associated protein OS=Homo sapiens OX=9606 GN=APMAP PE=1 SV=2 5.83 2311.5 - 1.24E+06 - - - -0.6374 - 1.624 0.484 - 219.1 1 2 0 -0.0007 9 0 0 0 1.62E+07 8.17E+06 - - - 4.0184 0.9977 221125_WJC_METTL3_EV_vs_WT_F04.11353.11353.2 0.0383 14-Sep K.NIHLNLDR.R "sp|Q9Y5S9|RBM8A_HUMAN,tr|A0A0J9YW13|A0A0J9YW13_HUMAN" 2 993.5356 2.53 45752 11353 2 993.53676 497.7751 RNA-binding protein 8A OS=Homo sapiens OX=9606 GN=RBM8A PE=1 SV=1 6.74 2311.6 - 1.14E+06 - - - 1.1897 - 1.463 0.242 - 350 1 2 0 0.0012 8 0 0 0 1.44E+07 5.68E+06 - - - 1.9756 0.9768 221125_WJC_METTL3_EV_vs_WT_F04.11355.11355.2 8.42 14-Jun K.TRPLLNIR.S "sp|P35226|BMI1_HUMAN,tr|Q5T8Z2|Q5T8Z2_HUMAN,tr|Q5T8Z6|Q5T8Z6_HUMAN,tr|R4GMX3|R4GMX3_HUMAN,tr|Q5T8Z4|Q5T8Z4_HUMAN" 5 981.6083 1.57 45754 11355 2 981.608635 491.8115 Polycomb complex protein BMI-1 OS=Homo sapiens OX=9606 GN=BMI1 PE=1 SV=2 12 2311.9 - 408180 - - - 0.2914 - 1.162 0.08 - 87.3 1 2 0 0.0003 8 0 0 0 2.99E+06 1.90E+06 - - - 0.0846 0.9087 221125_WJC_METTL3_EV_vs_WT_F04.11356.11356.2 2.41E-06 18-Oct L.VEFASKPAAR.K sp|P23246|SFPQ_HUMAN 1 1074.5822 0.91 45755 11356 2 1074.586013 538.2984 "Splicing factor, proline- and glutamine-rich OS=Homo sapiens OX=9606 GN=SFPQ PE=1 SV=2" 8.72 2312 - 381502 - - - 3.5539 - 2.169 0.356 - 442.3 1 1 0 0.0038 10 0 0 0 1.10E+07 1.22E+07 - - - 3.8304 0.9995 221125_WJC_METTL3_EV_vs_WT_F04.11362.11362.3 0.00573 Oct-44 K.GGGHVAQIYAIR.Q "sp|P62249|RS16_HUMAN,tr|M0R210|M0R210_HUMAN,tr|M0R3H0|M0R3H0_HUMAN,tr|M0QX76|M0QX76_HUMAN,tr|M0R1M5|M0R1M5_HUMAN" 5 1240.6677 0.83 45760 11362 3 1240.668539 414.5632 40S ribosomal protein S16 OS=Homo sapiens OX=9606 GN=RPS16 PE=1 SV=2 8.75 2312.7 - 4.26E+06 - - - 0.7125 - 1.911 0.316 - 135.4 1 2 0 0.0009 12 0 0 0 6.85E+07 8.28E+07 - - - 3.858 0.9999 221125_WJC_METTL3_EV_vs_WT_F04.11364.11364.2 8.74E-05 18-Sep K.EDQTEYLEER.R "sp|P08238|HS90B_HUMAN,sp|Q58FF6|H90B4_HUMAN,sp|Q58FF7|H90B3_HUMAN,sp|P07900|HS90A_HUMAN,tr|G3V2J8|G3V2J8_HUMAN" 5 1310.5626 0.87 45762 11364 2 1310.562843 656.2886 Heat shock protein HSP 90-beta OS=Homo sapiens OX=9606 GN=HSP90AB1 PE=1 SV=4 3.91 2312.9 - 3.22E+06 - - - 0.1549 - 2.091 0.515 - 456.4 1 2 0 0.0002 10 0 0 0 2.25E+07 2.59E+07 - - - 4.9037 0.9998 221125_WJC_METTL3_EV_vs_WT_F04.11366.11366.3 0.0156 Nov-40 K.EDVFVHQTAIK[136.11].R "sp|Q9Y2T7|YBOX2_HUMAN,sp|P67809|YBOX1_HUMAN,sp|P16989|YBOX3_HUMAN,tr|H0Y449|H0Y449_HUMAN,tr|A0A0D9SEI8|A0A0D9SEI8_HUMAN" 5 1293.6809 1.17 45764 11366 3 1293.681639 432.2342 Y-box-binding protein 2 OS=Homo sapiens OX=9606 GN=YBX2 PE=1 SV=2 5.32 2313 - 2.88E+06 - - - 0.6083 - 2.079 0.339 - 187.1 1 2 0 0.0008 11 0 0 0 9.60E+07 8.22E+07 - - - 4.3985 0.992 221125_WJC_METTL3_EV_vs_WT_F04.11367.11367.2 3.71E-05 18-Oct L.SFETTDESLR.S "sp|Q32P51|RA1L2_HUMAN,sp|P09651|ROA1_HUMAN,tr|F8W646|F8W646_HUMAN,tr|F8VZ49|F8VZ49_HUMAN,tr|A0A7I2V3R8|A0A7I2V3R8_HUMAN,tr|F8VTQ5|F8VTQ5_HUMAN,tr|A0A7I2YQ85|A0A7I2YQ85_HUMAN,tr|F8W6I7|F8W6I7_HUMAN,tr|A0A7I2V2L6|A0A7I2V2L6_HUMAN,tr|A0A7I2V3W0|A0A7I2V3W0_HUMAN" 10 1183.5357 1.26 45765 11367 2 1183.536091 592.7751 Heterogeneous nuclear ribonucleoprotein A1-like 2 OS=Homo sapiens OX=9606 GN=HNRNPA1L2 PE=2 SV=2 4.14 2313.1 - 2.03E+06 - - - 0.3329 - 2.042 0.504 - 294.6 1 1 0 0.0004 10 0 0 0 2.44E+07 1.93E+07 - - - 4.7562 0.9915 221125_WJC_METTL3_EV_vs_WT_F04.11368.11368.2 0.0332 18-Sep L.SFETTDESLR[166.11].S "sp|Q32P51|RA1L2_HUMAN,sp|P09651|ROA1_HUMAN,tr|F8W646|F8W646_HUMAN,tr|F8VZ49|F8VZ49_HUMAN,tr|A0A7I2V3R8|A0A7I2V3R8_HUMAN,tr|F8VTQ5|F8VTQ5_HUMAN,tr|A0A7I2YQ85|A0A7I2YQ85_HUMAN,tr|F8W6I7|F8W6I7_HUMAN,tr|A0A7I2V2L6|A0A7I2V2L6_HUMAN,tr|A0A7I2V3W0|A0A7I2V3W0_HUMAN" 10 1193.544 1.26 45766 11368 2 1193.54469 597.7793 Heterogeneous nuclear ribonucleoprotein A1-like 2 OS=Homo sapiens OX=9606 GN=HNRNPA1L2 PE=2 SV=2 4.14 2313.1 - 1.99E+06 - - - 0.6058 - 2.216 0.477 - 212.9 1 1 0 0.0007 10 0 0 0 2.46E+07 1.96E+07 - - - 4.7849 0.9998 221125_WJC_METTL3_EV_vs_WT_F04.11369.11369.3 0.0195 13/40 R.TGFAVIHDAAR[166.11].A sp|P42773|CDN2C_HUMAN 1 1166.6072 7.1 45767 11369 3 1166.606377 389.8763 Cyclin-dependent kinase 4 inhibitor C OS=Homo sapiens OX=9606 GN=CDKN2C PE=1 SV=1 6.41 2313.2 - 956608 - - - -0.6849 - 2.258 0.336 - 304.4 1 2 0 -0.0008 11 0 0 0 5.13E+07 7.22E+06 - - - 4.5996 0.9964 221125_WJC_METTL3_EV_vs_WT_F04.11371.11371.2 0.191 14-Jul K.NIHLNLDR[166.11].R "sp|Q9Y5S9|RBM8A_HUMAN,tr|A0A0J9YW13|A0A0J9YW13_HUMAN" 2 1003.5438 2.57 45769 11371 2 1003.54441 502.7792 RNA-binding protein 8A OS=Homo sapiens OX=9606 GN=RBM8A PE=1 SV=1 6.74 2313.4 - 814989 - - - 0.56 - 1.319 0.209 - 203.2 1 2 0 0.0006 8 0 0 0 1.44E+07 5.59E+06 - - - 1.4195 0.9983 221125_WJC_METTL3_EV_vs_WT_F04.11372.11372.2 0.335 14-Sep R.RVAQDWLK.E "sp|Q16891|MIC60_HUMAN,tr|B9A067|B9A067_HUMAN,tr|A0A087WYS0|A0A087WYS0_HUMAN,tr|C9J406|C9J406_HUMAN,tr|H7C463|H7C463_HUMAN" 5 1014.5611 1.45 45770 11372 2 1014.561706 508.2878 MICOS complex subunit MIC60 OS=Homo sapiens OX=9606 GN=IMMT PE=1 SV=1 8.75 2313.6 - 623831 - - - 0.6328 - 1.763 0.174 - 435 1 2 0 0.0006 8 0 0 0 5.21E+07 3.60E+07 - - - 2.0361 0.9992 221125_WJC_METTL3_EV_vs_WT_F04.11373.11373.2 0.00465 20-Nov K.STANGNLLEPR.T "sp|Q96HA1|P121A_HUMAN,sp|A8CG34|P121C_HUMAN" 2 1170.5993 1.22 45771 11373 2 1170.601526 586.3069 Nuclear envelope pore membrane protein POM 121 OS=Homo sapiens OX=9606 GN=POM121 PE=1 SV=2 5.72 2313.7 - 502942 - - - 1.9016 - 1.811 0.362 - 435.3 1 2 0 0.0022 11 0 0 0 3.99E+06 3.26E+06 - - - 3.3206 0.9999 221125_WJC_METTL3_EV_vs_WT_F04.11375.11375.3 1.25E-05 15/36 K.IPVFDAGHER[166.11].R "sp|Q9NPF5|DMAP1_HUMAN,tr|Q5TG39|Q5TG39_HUMAN,tr|Q5TG38|Q5TG38_HUMAN,tr|Q5TG40|Q5TG40_HUMAN" 4 1149.5806 1.21 45773 11375 3 1149.577881 384.2008 DNA methyltransferase 1-associated protein 1 OS=Homo sapiens OX=9606 GN=DMAP1 PE=1 SV=1 5.32 2313.9 - 477111 - - - -2.3887 - 2.549 0.442 - 278.1 1 2 0 -0.0027 10 0 0 0 5.16E+07 4.27E+07 - - - 6.1998 0.9999 221125_WJC_METTL3_EV_vs_WT_F04.11378.11378.2 0.000749 22-Aug R.LDEC[160.03]EEAFQGTK[136.11].V "sp|P61289|PSME3_HUMAN,tr|K7ENH2|K7ENH2_HUMAN,tr|B3KQ25|B3KQ25_HUMAN,tr|K7ESG5|K7ESG5_HUMAN,tr|K9J957|K9J957_HUMAN,tr|K7EMD0|K7EMD0_HUMAN,tr|K7EKR3|K7EKR3_HUMAN,tr|K7EPX6|K7EPX6_HUMAN" 8 1433.6224 1.35 45776 11378 2 1433.62197 717.8185 Proteasome activator complex subunit 3 OS=Homo sapiens OX=9606 GN=PSME3 PE=1 SV=1 4 2314.3 - 197048 - - - -0.3069 - 1.97 0.5 - 160.6 1 2 0 -0.0004 12 0 0 0 6.20E+06 4.59E+06 - - - 4.5179 0.9996 221125_WJC_METTL3_EV_vs_WT_F04.11382.11382.2 0.000279 18-Sep K.DTEPLIQTAK.T "sp|P48643|TCPE_HUMAN,tr|E9PCA1|E9PCA1_HUMAN,tr|B7ZAR1|B7ZAR1_HUMAN,tr|E7ENZ3|E7ENZ3_HUMAN" 4 1114.587 0.71 45778 11382 2 1114.588244 558.3008 T-complex protein 1 subunit epsilon OS=Homo sapiens OX=9606 GN=CCT5 PE=1 SV=1 4.37 2314.8 - 2.40E+06 - - - 1.1125 - 1.718 0.415 - 293.5 1 2 0 0.0012 10 0 0 0 1.32E+08 1.85E+08 - - - 3.6163 0.9999 221125_WJC_METTL3_EV_vs_WT_F04.11384.11384.2 9.64E-07 20-Aug K.NFYQEHPDLAR.R "sp|P17844|DDX5_HUMAN,tr|J3QR02|J3QR02_HUMAN,tr|X6RLV5|X6RLV5_HUMAN,tr|A0A7I2V507|A0A7I2V507_HUMAN,tr|J3KTA4|J3KTA4_HUMAN,tr|J3KTQ4|J3KTQ4_HUMAN,tr|A0A7I2V2S0|A0A7I2V2S0_HUMAN,tr|J3QRQ7|J3QRQ7_HUMAN" 8 1388.6473 1.61 45780 11384 2 1388.646348 695.3309 Probable ATP-dependent RNA helicase DDX5 OS=Homo sapiens OX=9606 GN=DDX5 PE=1 SV=1 5.32 2314.9 - 1.38E+06 - - - -0.6949 - 1.973 0.595 - 263.6 1 2 0 -0.001 11 0 0 0 2.80E+07 1.74E+07 - - - 5.2737 0.9996 221125_WJC_METTL3_EV_vs_WT_F04.11385.11385.2 0.0088 16-Aug K.FWETDESSK[136.11].D "sp|Q14671|PUM1_HUMAN,tr|Q5T1Z8|Q5T1Z8_HUMAN,tr|H0YEH2|H0YEH2_HUMAN,tr|Q5T1Z4|Q5T1Z4_HUMAN" 4 1135.4913 2.32 45781 11385 2 1135.491687 568.7529 Pumilio homolog 1 OS=Homo sapiens OX=9606 GN=PUM1 PE=1 SV=3 4.14 2315 - 1.15E+06 - - - 0.3241 - 1.697 0.38 - 217.5 1 2 0 0.0004 9 0 0 0 1.10E+08 4.75E+07 - - - 3.3776 0.9999 221125_WJC_METTL3_EV_vs_WT_F04.11386.11386.3 0.00019 Nov-36 R.RLSEDYGVLK.T "sp|P32119|PRDX2_HUMAN,tr|A6NIW5|A6NIW5_HUMAN" 2 1178.6295 1.01 45782 11386 3 1178.62796 393.8838 Peroxiredoxin-2 OS=Homo sapiens OX=9606 GN=PRDX2 PE=1 SV=5 6.07 2315.1 - 802604 - - - -1.3388 - 2.31 0.358 - 195.9 1 2 0 -0.0016 10 0 0 0 1.40E+07 1.38E+07 - - - 4.976 0.9998 221125_WJC_METTL3_EV_vs_WT_F04.11387.11387.2 0.00298 14-Dec R.HLDQIIPR[166.11].M sp|Q92616|GCN1_HUMAN 1 1000.5693 0.88 45783 11387 2 1000.568558 501.2919 eIF-2-alpha kinase activator GCN1 OS=Homo sapiens OX=9606 GN=GCN1 PE=1 SV=6 6.74 2315.2 - 739009 - - - -0.7756 - 2.067 0.414 - 537.2 1 2 0 -0.0008 8 0 0 0 5.09E+06 5.76E+06 - - - 4.2884 0.999 221125_WJC_METTL3_EV_vs_WT_F04.11388.11388.2 0.0016 18-Dec R.RLSEDYGVLK.T "sp|P32119|PRDX2_HUMAN,tr|A6NIW5|A6NIW5_HUMAN" 2 1178.6295 0.94 45784 11388 2 1178.626203 590.322 Peroxiredoxin-2 OS=Homo sapiens OX=9606 GN=PRDX2 PE=1 SV=5 6.07 2315.4 - 648233 - - - -2.8296 - 2.179 0.354 - 610.5 1 2 0 -0.0033 10 0 0 0 1.38E+07 1.47E+07 - - - 3.8286 0.9987 221125_WJC_METTL3_EV_vs_WT_F04.11389.11389.2 0.00309 18-Jun K.ELENEYAINK.F sp|P35453|HXD13_HUMAN 1 1221.5877 4.29 45785 11389 2 1221.586252 611.8011 Homeobox protein Hox-D13 OS=Homo sapiens OX=9606 GN=HOXD13 PE=1 SV=3 4.25 2315.5 - 629683 - - - -1.2124 - 1.515 0.293 - 111.6 1 2 0 -0.0015 10 0 0 0 5.52E+06 1.29E+06 - - - 2.3642 1 221125_WJC_METTL3_EV_vs_WT_F04.11390.11390.2 1.01E-08 13/20 K.C[160.03]PLC[160.03]QESNFTR.Q "sp|Q8WVD3|RN138_HUMAN,tr|J3QLQ3|J3QLQ3_HUMAN" 2 1410.602 1.45 45786 11390 2 1410.6013 706.3083 E3 ubiquitin-protein ligase RNF138 OS=Homo sapiens OX=9606 GN=RNF138 PE=1 SV=1 5.99 2315.6 - 514284 - - - -0.5104 - 2.479 0.647 - 679.5 1 2 0 -0.0007 11 0 0 0 4.71E+07 3.24E+07 - - - 6.2755 0.9999 221125_WJC_METTL3_EV_vs_WT_F04.11391.11391.2 0.00188 22-Sep R.LDEC[160.03]EEAFQGTK.V "sp|P61289|PSME3_HUMAN,tr|K7ENH2|K7ENH2_HUMAN,tr|B3KQ25|B3KQ25_HUMAN,tr|K7ESG5|K7ESG5_HUMAN,tr|K9J957|K9J957_HUMAN,tr|K7EMD0|K7EMD0_HUMAN,tr|K7EKR3|K7EKR3_HUMAN,tr|K7EPX6|K7EPX6_HUMAN" 8 1425.6082 1.35 45787 11391 2 1425.607907 713.8114 Proteasome activator complex subunit 3 OS=Homo sapiens OX=9606 GN=PSME3 PE=1 SV=1 4 2315.7 - 463093 - - - -0.2125 - 2.151 0.526 - 250.2 1 2 0 -0.0003 12 0 0 0 6.20E+06 4.59E+06 - - - 4.9412 0.9951 221125_WJC_METTL3_EV_vs_WT_F04.11395.11395.2 0.0318 26-Jul R.LPVGTGTSLNGTSR.G "sp|Q9BVV6|TALD3_HUMAN,tr|A0A494C0M8|A0A494C0M8_HUMAN,tr|A0A494C0Z1|A0A494C0Z1_HUMAN,tr|A0A494C171|A0A494C171_HUMAN" 4 1358.7154 0.64 45791 11395 2 1358.720199 680.365 Protein TALPID3 OS=Homo sapiens OX=9606 GN=KIAA0586 PE=1 SV=4 9.75 2316.3 - 252204 - - - 3.5372 - 1.677 0.314 - 72.7 1 2 0 0.0048 14 0 0 0 1.42E+06 2.23E+06 - - - 2.6561 0.9997 221125_WJC_METTL3_EV_vs_WT_F04.11398.11398.2 0.00302 18-Oct K.DYTVTQVPPK.H "sp|Q8N5Z5|KCD17_HUMAN,tr|A0A087WX35|A0A087WX35_HUMAN,tr|H0Y731|H0Y731_HUMAN" 3 1146.5921 6.08 45793 11398 2 1146.592627 574.3033 BTB\POZ domain-containing protein KCTD17 OS=Homo sapiens OX=9606 GN=KCTD17 PE=1 SV=3 5.83 2316.7 - 984051 - - - 0.4683 - 1.834 0.404 - 333.2 1 2 0 0.0005 10 0 0 0 1.38E+07 2.27E+06 - - - 3.7177 0.9998 221125_WJC_METTL3_EV_vs_WT_F04.11401.11401.2 5.03E-05 16-Sep R.EYQELMNTK.L "sp|P13647|K2C5_HUMAN,tr|H0YI76|H0YI76_HUMAN" 2 1154.5278 857.25 45795 11401 2 1154.528079 578.2712 "Keratin, type II cytoskeletal 5 OS=Homo sapiens OX=9606 GN=KRT5 PE=1 SV=3" 4.53 2317 - 7.92E+06 - - - 0.2633 - 1.567 0.504 - 312.4 1 2 0 0.0003 9 0 0 0 3.67E+08 4.28E+05 - - - 4.0629 0.9998 221125_WJC_METTL3_EV_vs_WT_F04.11402.11402.2 0.00435 18-Sep K.DTEPLIQTAK[136.11].T "sp|P48643|TCPE_HUMAN,tr|E9PCA1|E9PCA1_HUMAN,tr|B7ZAR1|B7ZAR1_HUMAN,tr|E7ENZ3|E7ENZ3_HUMAN" 4 1122.6012 0.71 45796 11402 2 1122.601327 562.3079 T-complex protein 1 subunit epsilon OS=Homo sapiens OX=9606 GN=CCT5 PE=1 SV=1 4.37 2317 - 7.21E+06 - - - 0.1096 - 1.799 0.496 - 322.2 1 2 0 0.0001 10 0 0 0 1.32E+08 1.85E+08 - - - 4.3436 0.9997 221125_WJC_METTL3_EV_vs_WT_F04.11403.11403.2 0.000117 16-Sep K.FWETDESSK.D "sp|Q14671|PUM1_HUMAN,tr|Q5T1Z8|Q5T1Z8_HUMAN,tr|H0YEH2|H0YEH2_HUMAN,tr|Q5T1Z4|Q5T1Z4_HUMAN" 4 1127.4771 2.31 45797 11403 2 1127.47907 564.7458 Pumilio homolog 1 OS=Homo sapiens OX=9606 GN=PUM1 PE=1 SV=3 4.14 2317.1 - 5.62E+06 - - - 1.7304 - 1.779 0.525 - 296 1 2 0 0.002 9 0 0 0 1.12E+08 4.86E+07 - - - 4.5846 1 221125_WJC_METTL3_EV_vs_WT_F04.11406.11406.2 7.82E-10 13/20 K.NFYQEHPDLAR[166.11].R "sp|P17844|DDX5_HUMAN,tr|J3QR02|J3QR02_HUMAN,tr|X6RLV5|X6RLV5_HUMAN,tr|A0A7I2V507|A0A7I2V507_HUMAN,tr|J3KTA4|J3KTA4_HUMAN,tr|J3KTQ4|J3KTQ4_HUMAN,tr|A0A7I2V2S0|A0A7I2V2S0_HUMAN,tr|J3QRQ7|J3QRQ7_HUMAN" 8 1398.6556 1.6 45800 11406 2 1398.655785 700.3351 Probable ATP-dependent RNA helicase DDX5 OS=Homo sapiens OX=9606 GN=DDX5 PE=1 SV=1 5.32 2317.3 - 1.58E+06 - - - 0.1444 - 2.485 0.645 - 776.7 1 2 0 0.0002 11 0 0 0 2.79E+07 1.74E+07 - - - 6.2674 1 221125_WJC_METTL3_EV_vs_WT_F04.11407.11407.2 3.82E-08 20-Dec K.C[160.03]PLC[160.03]QESNFTR[166.11].Q "sp|Q8WVD3|RN138_HUMAN,tr|J3QLQ3|J3QLQ3_HUMAN" 2 1420.6103 1.45 45801 11407 2 1420.609329 711.3124 E3 ubiquitin-protein ligase RNF138 OS=Homo sapiens OX=9606 GN=RNF138 PE=1 SV=1 5.99 2317.4 - 1.37E+06 - - - -0.6765 - 2.434 0.676 - 641.5 1 2 0 -0.001 11 0 0 0 4.71E+07 3.24E+07 - - - 6.44 0.9994 221125_WJC_METTL3_EV_vs_WT_F04.11409.11409.2 0.00402 14-Aug R.GLDVEDVK[136.11].F "sp|Q92841|DDX17_HUMAN,sp|P17844|DDX5_HUMAN,tr|A0A5H1ZRQ2|A0A5H1ZRQ2_HUMAN,tr|J3KTA4|J3KTA4_HUMAN,tr|A0A0G2JLI4|A0A0G2JLI4_HUMAN,tr|A0A1X7SBZ2|A0A1X7SBZ2_HUMAN" 6 881.4586 1.84 45803 11409 2 881.457631 441.7366 Probable ATP-dependent RNA helicase DDX17 OS=Homo sapiens OX=9606 GN=DDX17 PE=1 SV=2 4.03 2317.6 - 683753 - - - -1.0573 - 1.535 0.361 - 172.3 1 2 0 -0.0009 8 0 0 0 1.15E+07 6.29E+06 - - - 2.9995 0.9994 221125_WJC_METTL3_EV_vs_WT_F04.11410.11410.2 0.0079 14-Sep K.SWNDC[160.03]LNK[136.11].E sp|Q9Y5B9|SP16H_HUMAN 1 1043.4586 0.91 45804 11410 2 1043.459011 522.7366 FACT complex subunit SPT16 OS=Homo sapiens OX=9606 GN=SUPT16H PE=1 SV=1 5.55 2317.7 - 573480 - - - 0.413 - 1.377 0.39 - 297.8 1 2 0 0.0004 8 0 0 0 4.45E+06 4.87E+06 - - - 2.8862 0.9993 221125_WJC_METTL3_EV_vs_WT_F04.11411.11411.3 0.000146 Oct-40 K.C[160.03]DLVLDAAHEK[136.11].S "sp|Q99700|ATX2_HUMAN,tr|A0A5F9ZHW5|A0A5F9ZHW5_HUMAN,tr|A0A5F9ZHH4|A0A5F9ZHH4_HUMAN,tr|A0A5F9ZI57|A0A5F9ZI57_HUMAN,tr|A0A2R8YDM9|A0A2R8YDM9_HUMAN,tr|F8VQP2|F8VQP2_HUMAN,tr|A0A2R8Y5A6|A0A2R8Y5A6_HUMAN,tr|F8WB06|F8WB06_HUMAN,tr|A0A5F9ZH85|A0A5F9ZH85_HUMAN,tr|V9GY86|V9GY86_HUMAN,tr|A0A2R8Y7E6|A0A2R8Y7E6_HUMAN,tr|A0A5F9ZHX3|A0A5F9ZHX3_HUMAN,tr|H0YH87|H0YH87_HUMAN,tr|A0A2R8Y7P6|A0A2R8Y7P6_HUMAN" 14 1277.6165 0.92 45805 11411 3 1277.611424 426.8795 Ataxin-2 OS=Homo sapiens OX=9606 GN=ATXN2 PE=1 SV=2 4.54 2317.7 - 675836 - - - -4.002 - 1.876 0.441 - 124 1 2 0 -0.0051 11 0 0 0 6.65E+06 7.20E+06 - - - 5.2426 0.9628 221125_WJC_METTL3_EV_vs_WT_F04.11413.11413.2 0.0376 20-Oct K.HLLIGVSSDR[166.11]G.L sp|P36542|ATPG_HUMAN 1 1162.6334 0.96 45807 11413 2 1162.633283 582.324 "ATP synthase subunit gamma, mitochondrial OS=Homo sapiens OX=9606 GN=ATP5F1C PE=1 SV=1" 6.74 2318 - 421883 - - - -0.0929 - 1.651 0.321 - 355.4 1 1 0 -0.0001 11 0 0 0 6.86E+06 7.15E+06 - - - 2.7682 0.9695 221125_WJC_METTL3_EV_vs_WT_F04.11415.11415.2 5.20E-06 15/24 Y.TIDTENSTVALAK[136.11].V "sp|Q8ND56|LS14A_HUMAN,tr|I3L4Q1|I3L4Q1_HUMAN,tr|A0A140TA76|A0A140TA76_HUMAN,tr|K7EMZ9|K7EMZ9_HUMAN" 4 1369.718 1.05 45809 11415 2 1369.722651 685.8663 Protein LSM14 homolog A OS=Homo sapiens OX=9606 GN=LSM14A PE=1 SV=3 4.37 2318.3 - 245373 - - - 3.3773 - 2.71 0.536 - 403.1 1 1 0 0.0046 13 0 0 0 4.02E+07 3.81E+07 - - - 5.5571 0.9985 221125_WJC_METTL3_EV_vs_WT_F04.11418.11418.3 0.0192 Nov-52 R.ALVNHSGLSAPVPR[166.11].G sp|Q9P2D1|CHD7_HUMAN 1 1426.792 1.28 45811 11418 3 1426.790433 476.6046 Chromodomain-helicase-DNA-binding protein 7 OS=Homo sapiens OX=9606 GN=CHD7 PE=1 SV=3 9.8 2318.6 - 645091 - - - -1.1102 - 1.798 0.267 - 155.6 1 2 0 -0.0016 14 0 0 0 1.51E+07 1.18E+07 - - - 3.0755 0.9948 221125_WJC_METTL3_EV_vs_WT_F04.11420.11420.2 3.92 14/24 Y.TIDTENSTVALAK.V "sp|Q8ND56|LS14A_HUMAN,tr|I3L4Q1|I3L4Q1_HUMAN,tr|A0A140TA76|A0A140TA76_HUMAN,tr|K7EMZ9|K7EMZ9_HUMAN" 4 1361.7038 1 45812 11420 2 1361.70405 681.8592 Protein LSM14 homolog A OS=Homo sapiens OX=9606 GN=LSM14A PE=1 SV=3 4.37 2318.8 - 984148 - - - 0.1652 - 2.568 0.555 - 335.9 1 1 0 0.0002 13 0 0 0 3.79E+07 3.80E+07 - - - 5.5607 0.9951 221125_WJC_METTL3_EV_vs_WT_F04.11421.11421.2 0.201 14-Sep R.R[166.11]FSDIQIR[166.11].R "sp|P11586|C1TC_HUMAN,tr|F5H2F4|F5H2F4_HUMAN,tr|V9GZ78|V9GZ78_HUMAN,tr|V9GYY3|V9GYY3_HUMAN,tr|A0A494C1T2|A0A494C1T2_HUMAN" 5 1053.5834 0.43 45813 11421 2 1053.583135 527.799 "C-1-tetrahydrofolate synthase, cytoplasmic OS=Homo sapiens OX=9606 GN=MTHFD1 PE=1 SV=4" 9.6 2319 - 605401 - - - -0.2686 - 1.68 0.069 - 262 1 2 0 -0.0003 8 0 0 0 3.19E+06 7.47E+06 - - - 1.1152 0.9999 221125_WJC_METTL3_EV_vs_WT_F04.11422.11422.2 0.000189 22-Dec R.TLIQNC[160.03]GASTIR.L "sp|P49368|TCPG_HUMAN,tr|B4DUR8|B4DUR8_HUMAN" 2 1332.682 0.16 45814 11422 2 1332.682692 667.3483 T-complex protein 1 subunit gamma OS=Homo sapiens OX=9606 GN=CCT3 PE=1 SV=4 7.91 2319.1 - 1.06E+06 - - - 0.5313 - 2.403 0.494 - 473.1 1 2 0 0.0007 12 0 0 0 2.40E+07 1.49E+08 - - - 4.9963 0.9985 221125_WJC_METTL3_EV_vs_WT_F04.11423.11423.2 0.000128 16-Sep R.KMNALFEGR.R sp|Q9H307|PININ_HUMAN 1 1064.5437 1.52 45815 11423 2 1064.543488 533.2791 Pinin OS=Homo sapiens OX=9606 GN=PNN PE=1 SV=5 8.75 2319.2 - 690980 - - - -0.1991 - 1.903 0.151 - 328.4 1 2 0 -0.0002 9 0 0 0 8.20E+06 5.41E+06 - - - 2.0177 0.9118 221125_WJC_METTL3_EV_vs_WT_F04.11426.11426.2 0.0151 18-Jun K.LFNPPEESEK.- "sp|Q9NRP2|COXM2_HUMAN,tr|H3BPP2|H3BPP2_HUMAN" 2 1188.5663 2.82 45818 11426 2 1188.572355 595.2904 COX assembly mitochondrial protein 2 homolog OS=Homo sapiens OX=9606 GN=CMC2 PE=1 SV=1 4.25 2319.6 - 271305 - - - 5.1205 - 1.137 0.242 - 110.2 1 2 0 0.0061 10 0 0 0 7.62E+06 2.71E+06 - - - 1.1849 0.8971 221125_WJC_METTL3_EV_vs_WT_F04.11427.11427.2 0.00451 16-Jul L.PVFDAGHER.R "sp|Q9NPF5|DMAP1_HUMAN,tr|Q5TG39|Q5TG39_HUMAN,tr|Q5TG38|Q5TG38_HUMAN,tr|Q5TG40|Q5TG40_HUMAN" 4 1026.4883 0.84 45819 11427 2 1026.484751 514.2514 DNA methyltransferase 1-associated protein 1 OS=Homo sapiens OX=9606 GN=DMAP1 PE=1 SV=1 5.33 2319.7 - 230266 - - - -3.4506 - 1.644 0.416 - 159.1 1 1 0 -0.0035 9 0 0 0 3.36E+06 3.99E+06 - - - 3.5507 0.9872 221125_WJC_METTL3_EV_vs_WT_F04.11429.11429.2 0.285 14-Sep R.NSITVPYK.V sp|Q00577|PURA_HUMAN 1 920.4967 1.19 45820 11429 2 920.499044 461.2556 Transcriptional activator protein Pur-alpha OS=Homo sapiens OX=9606 GN=PURA PE=1 SV=2 8.59 2319.9 - 466968 - - - 2.5106 - 1.531 0.128 - 282.5 1 2 0 0.0023 8 0 0 0 8.37E+06 7.03E+06 - - - 1.2702 0.9992 221125_WJC_METTL3_EV_vs_WT_F04.11432.11432.2 3.46E-05 24-Dec R.ATAGAYIASQTVK.K "sp|P28074|PSB5_HUMAN,tr|H0YJM8|H0YJM8_HUMAN" 2 1279.6772 0.57 45822 11432 2 1279.678795 640.8459 Proteasome subunit beta type-5 OS=Homo sapiens OX=9606 GN=PSMB5 PE=1 SV=3 8.63 2320.2 - 1.39E+06 - - - 1.2339 - 2.515 0.21 - 485.7 1 2 0 0.0016 13 0 0 0 1.27E+07 2.23E+07 - - - 2.9586 0.9999 221125_WJC_METTL3_EV_vs_WT_F04.11434.11434.2 2.55E-05 28-Dec K.LAGEELAGEEAPQEK[136.11].A "sp|Q7Z4V5|HDGR2_HUMAN,tr|A0A087WX58|A0A087WX58_HUMAN,tr|K7EPS6|K7EPS6_HUMAN" 3 1577.7664 0.93 45824 11434 2 1577.766582 789.8905 Hepatoma-derived growth factor-related protein 2 OS=Homo sapiens OX=9606 GN=HDGFL2 PE=1 SV=1 3.98 2320.5 - 663895 - - - 0.0951 - 2.526 0.45 - 278.2 1 2 0 0.0001 15 0 0 0 8.93E+06 9.62E+06 - - - 4.6428 0.9999 221125_WJC_METTL3_EV_vs_WT_F04.11435.11435.2 4.20E-08 17/28 K.LAGEELAGEEAPQEK.A "sp|Q7Z4V5|HDGR2_HUMAN,tr|A0A087WX58|A0A087WX58_HUMAN,tr|K7EPS6|K7EPS6_HUMAN" 3 1569.7522 0.93 45825 11435 2 1569.750242 785.8834 Hepatoma-derived growth factor-related protein 2 OS=Homo sapiens OX=9606 GN=HDGFL2 PE=1 SV=1 3.98 2320.6 - 578684 - - - -1.2677 - 3.242 0.507 - 905.1 1 2 0 -0.002 15 0 0 0 8.93E+06 9.62E+06 - - - 5.6768 1 221125_WJC_METTL3_EV_vs_WT_F04.11436.11436.2 2.02E-05 20-Dec R.TSGAFVYDC[160.03]SK.F sp|Q12948|FOXC1_HUMAN 1 1233.5336 2.02 45826 11436 2 1233.535452 617.7741 Forkhead box protein C1 OS=Homo sapiens OX=9606 GN=FOXC1 PE=1 SV=3 5.5 2320.7 - 526512 - - - 1.5103 - 2.33 0.637 - 755.8 1 2 0 0.0019 11 0 0 0 3.88E+07 1.92E+07 - - - 6.0336 0.9559 221125_WJC_METTL3_EV_vs_WT_F04.11438.11438.3 0.0016 Aug-40 K.HLLIGVSSDR[166.11]G.L sp|P36542|ATPG_HUMAN 1 1162.6334 1.09 45828 11438 3 1162.632117 388.5517 "ATP synthase subunit gamma, mitochondrial OS=Homo sapiens OX=9606 GN=ATP5F1C PE=1 SV=1" 6.74 2321 - 472398 - - - -1.0958 - 1.712 0.349 - 82.9 1 1 0 -0.0013 11 0 0 0 3.68E+06 3.38E+06 - - - 3.9581 0.9065 221125_WJC_METTL3_EV_vs_WT_F04.11439.11439.3 0.108 Sep-40 K.NISLHGDGPLR[166.11].L "sp|Q8IZL8|PELP1_HUMAN,tr|E7EV54|E7EV54_HUMAN,tr|C9JFV4|C9JFV4_HUMAN,tr|I3L445|I3L445_HUMAN" 4 1187.6286 1.8 45829 11439 3 1187.629303 396.8835 "Proline-, glutamic acid- and leucine-rich protein 1 OS=Homo sapiens OX=9606 GN=PELP1 PE=1 SV=2" 6.74 2321.1 - 297737 - - - 0.5583 - 1.568 0.06 - 85 1 2 0 0.0007 11 0 0 0 5.95E+06 3.30E+06 - - - 0.4866 0.9998 221125_WJC_METTL3_EV_vs_WT_F04.11443.11443.2 1.88E-05 22-Oct K.GIVEFASKPAAR.K sp|P23246|SFPQ_HUMAN 1 1244.6877 0.88 45832 11443 2 1244.688596 623.3511 "Splicing factor, proline- and glutamine-rich OS=Homo sapiens OX=9606 GN=SFPQ PE=1 SV=2" 8.75 2321.7 - 409323 - - - 0.703 - 2.028 0.498 - 435.3 1 2 0 0.0009 12 0 0 0 1.72E+07 1.96E+07 - - - 4.5793 0.9941 221125_WJC_METTL3_EV_vs_WT_F04.11445.11445.2 3.42E-07 13/22 S.SFTAAPTGTTIK.F "sp|P52948|NUP98_HUMAN,tr|A0A3B3ITD8|A0A3B3ITD8_HUMAN" 2 1193.6292 1.53 45833 11445 2 1193.628783 597.8219 Nuclear pore complex protein Nup98-Nup96 OS=Homo sapiens OX=9606 GN=NUP98 PE=1 SV=4 8.47 2321.9 - 1.45E+06 - - - -0.3519 - 2.215 0.558 - 424.8 1 1 0 -0.0004 12 0 0 0 1.52E+07 9.93E+06 - - - 5.2547 0.9997 221125_WJC_METTL3_EV_vs_WT_F04.11446.11446.2 0.0172 20-Oct R.GLGAIQPGVNR.C "sp|Q9UI36|DACH1_HUMAN,sp|Q96NX9|DACH2_HUMAN,tr|D6RFG7|D6RFG7_HUMAN,tr|D6REJ4|D6REJ4_HUMAN" 4 1080.604 2.28 45834 11446 2 1080.604425 541.3093 Dachshund homolog 1 OS=Homo sapiens OX=9606 GN=DACH1 PE=1 SV=4 9.75 2322 - 863791 - - - 0.4007 - 2.101 0.345 - 358.4 1 2 0 0.0004 11 0 0 0 9.69E+06 4.26E+06 - - - 3.5974 0.9999 221125_WJC_METTL3_EV_vs_WT_F04.11447.11447.2 2.13E-05 16-Sep R.NQAIEELEK.S "sp|Q9P289|STK26_HUMAN,tr|B4E0Y9|B4E0Y9_HUMAN,tr|Q8NBY1|Q8NBY1_HUMAN" 3 1072.5401 0.59 45835 11447 2 1072.539666 537.2773 Serine\threonine-protein kinase 26 OS=Homo sapiens OX=9606 GN=STK26 PE=1 SV=2 4.25 2322.1 - 808483 - - - -0.3618 - 2.057 0.482 - 469.9 1 2 0 -0.0004 9 0 0 0 5.64E+06 9.60E+06 - - - 4.6875 0.9998 221125_WJC_METTL3_EV_vs_WT_F04.11448.11448.3 7.99E-05 15/44 R.QAILGEHPSSFR[166.11].H "sp|Q8WVV9|HNRLL_HUMAN,tr|V9GYK2|V9GYK2_HUMAN,tr|C9IYN3|C9IYN3_HUMAN,tr|B7WPG3|B7WPG3_HUMAN" 4 1350.692 1.66 45836 11448 3 1350.693452 451.2379 Heterogeneous nuclear ribonucleoprotein L-like OS=Homo sapiens OX=9606 GN=HNRNPLL PE=1 SV=1 6.75 2322.2 - 779637 - - - 1.098 - 2.19 0.38 - 263.4 1 2 0 0.0015 12 0 0 0 1.13E+07 6.81E+06 - - - 4.9491 1 221125_WJC_METTL3_EV_vs_WT_F04.11450.11450.2 1.51E-06 13/20 R.TSGAFVYDC[160.03]SK[136.11].F sp|Q12948|FOXC1_HUMAN 1 1241.5478 2.02 45838 11450 2 1241.549211 621.7812 Forkhead box protein C1 OS=Homo sapiens OX=9606 GN=FOXC1 PE=1 SV=3 5.5 2322.5 - 652936 - - - 1.1453 - 2.579 0.608 - 907.7 1 2 0 0.0014 11 0 0 0 3.87E+07 1.92E+07 - - - 6.0942 0.9477 221125_WJC_METTL3_EV_vs_WT_F04.11451.11451.2 0.0139 24-Sep R.LLEGEDAHLSSQQ.A sp|P08779|K1C16_HUMAN 1 1425.6736 - 45839 11451 2 1425.673226 713.8441 "Keratin, type I cytoskeletal 16 OS=Homo sapiens OX=9606 GN=KRT16 PE=1 SV=4" 4.13 2322.6 - 611221 - - - -0.2532 - 1.321 0.364 - 146.7 1 1 0 -0.0004 13 0 0 0 - - - - - 2.4439 0.9998 221125_WJC_METTL3_EV_vs_WT_F04.11452.11452.3 2.28E-05 Dec-40 R.DPHLAC[160.03]VAYER.G "sp|Q00610|CLH1_HUMAN,sp|P53675|CLH2_HUMAN,tr|A0A087WVQ6|A0A087WVQ6_HUMAN,tr|A0A087WX41|A0A087WX41_HUMAN" 4 1329.6136 1.12 45840 11452 3 1329.611858 444.2118 Clathrin heavy chain 1 OS=Homo sapiens OX=9606 GN=CLTC PE=1 SV=5 5.32 2322.8 - 574923 - - - -1.2876 - 2.069 0.38 - 213.1 1 2 0 -0.0017 11 0 0 0 6.03E+06 5.39E+06 - - - 4.8416 0.9999 221125_WJC_METTL3_EV_vs_WT_F04.11453.11453.2 0.00827 16/26 K.LAQAAQSSVATITR.L sp|Q9Y490|TLN1_HUMAN 1 1415.7732 1.09 45841 11453 2 1415.772555 708.8939 Talin-1 OS=Homo sapiens OX=9606 GN=TLN1 PE=1 SV=3 9.75 2322.9 - 556342 - - - -0.4852 - 2.944 0.428 - 1289.7 1 2 0 -0.0007 14 0 0 0 5.23E+06 4.82E+06 - - - 4.9116 0.9704 221125_WJC_METTL3_EV_vs_WT_F04.11454.11454.3 0.0708 Sep-40 K.C[160.03]DLVLDAAHEK.S "sp|Q99700|ATX2_HUMAN,tr|A0A5F9ZHW5|A0A5F9ZHW5_HUMAN,tr|A0A5F9ZHH4|A0A5F9ZHH4_HUMAN,tr|A0A5F9ZI57|A0A5F9ZI57_HUMAN,tr|A0A2R8YDM9|A0A2R8YDM9_HUMAN,tr|F8VQP2|F8VQP2_HUMAN,tr|A0A2R8Y5A6|A0A2R8Y5A6_HUMAN,tr|F8WB06|F8WB06_HUMAN,tr|A0A5F9ZH85|A0A5F9ZH85_HUMAN,tr|V9GY86|V9GY86_HUMAN,tr|A0A2R8Y7E6|A0A2R8Y7E6_HUMAN,tr|A0A5F9ZHX3|A0A5F9ZHX3_HUMAN,tr|H0YH87|H0YH87_HUMAN,tr|A0A2R8Y7P6|A0A2R8Y7P6_HUMAN" 14 1269.6023 0.61 45842 11454 3 1269.602054 424.2081 Ataxin-2 OS=Homo sapiens OX=9606 GN=ATXN2 PE=1 SV=2 4.54 2323 - 508403 - - - -0.2229 - 1.286 0.171 - 108.6 1 2 0 -0.0003 11 0 0 0 4.39E+06 7.20E+06 - - - 1.161 1 221125_WJC_METTL3_EV_vs_WT_F04.11456.11456.3 0.000127 13/40 R.LSNLALVK[136.11]PEK[136.11].T "sp|O14737|PDCD5_HUMAN,tr|K7EQA1|K7EQA1_HUMAN" 2 1226.7569 1.53 45844 11456 3 1226.756377 409.9263 Programmed cell death protein 5 OS=Homo sapiens OX=9606 GN=PDCD5 PE=1 SV=3 8.59 2323.2 - 443884 - - - -0.4459 - 2.213 0.529 - 144.7 1 2 0 -0.0005 11 0 0 0 2.73E+07 1.79E+07 - - - 6.6943 0.9993 221125_WJC_METTL3_EV_vs_WT_F04.11459.11459.2 0.00142 14-Jul K.DVQLHLER.Q "sp|Q16514|TAF12_HUMAN,tr|A0A804HLG9|A0A804HLG9_HUMAN" 2 1008.5352 1.34 45847 11459 2 1008.535444 505.2749 Transcription initiation factor TFIID subunit 12 OS=Homo sapiens OX=9606 GN=TAF12 PE=1 SV=1 5.32 2323.6 - 286440 - - - 0.1993 - 1.447 0.35 - 245.6 1 2 0 0.0002 8 0 0 0 7.23E+06 5.41E+06 - - - 2.7404 0.9996 221125_WJC_METTL3_EV_vs_WT_F04.11462.11462.2 0.000268 18-Jul R.GVPQQIEVAR.Q sp|Q96I24|FUBP3_HUMAN 1 1095.6037 1.99 45849 11462 2 1095.604766 548.8091 Far upstream element-binding protein 3 OS=Homo sapiens OX=9606 GN=FUBP3 PE=1 SV=2 6 2324 - 1.95E+06 - - - 1.0122 - 1.632 0.435 - 223.3 1 2 0 0.0011 10 0 0 0 6.88E+07 3.46E+07 - - - 3.6208 0.9693 221125_WJC_METTL3_EV_vs_WT_F04.11463.11463.3 0.356 Jul-40 K.EDVFVHQTAIK.R "sp|Q9Y2T7|YBOX2_HUMAN,sp|P67809|YBOX1_HUMAN,sp|P16989|YBOX3_HUMAN,tr|H0Y449|H0Y449_HUMAN,tr|A0A0D9SEI8|A0A0D9SEI8_HUMAN" 5 1285.6667 1.17 45850 11463 3 1285.666563 429.5628 Y-box-binding protein 2 OS=Homo sapiens OX=9606 GN=YBX2 PE=1 SV=2 5.32 2324.1 - 770913 - - - -0.0692 - 1.378 0.164 - 69.3 2 2 0 -0.0001 11 0 0 0 9.60E+07 8.22E+07 - - - 1.14 0.9937 221125_WJC_METTL3_EV_vs_WT_F04.11465.11465.2 3.05E-05 14/24 R.LLEGEDAHLSSSQ.F sp|P02533|K1C14_HUMAN 1 1384.647 - 45852 11465 2 1384.647924 693.3308 "Keratin, type I cytoskeletal 14 OS=Homo sapiens OX=9606 GN=KRT14 PE=1 SV=4" 4.13 2324.2 - 1.59E+06 - - - 0.6399 - 2.456 0.548 - 351.9 1 1 0 0.0009 13 0 0 0 - - - - - 5.3944 0.984 221125_WJC_METTL3_EV_vs_WT_F04.11466.11466.2 0.00107 18-Sep L.SWQTTQEGLR.E sp|O43347|MSI1H_HUMAN 1 1204.5837 0.7 45853 11466 2 1204.58388 603.2991 RNA-binding protein Musashi homolog 1 OS=Homo sapiens OX=9606 GN=MSI1 PE=1 SV=1 5.72 2324.3 - 1.59E+06 - - - 0.1909 - 1.855 0.4 - 319.6 1 1 0 0.0002 10 0 0 0 1.32E+07 1.89E+07 - - - 3.72 0.9989 221125_WJC_METTL3_EV_vs_WT_F04.11468.11468.3 0.00954 Oct-44 R.AVIEHNLLSASK.L "sp|Q9BT78|CSN4_HUMAN,tr|D6RD63|D6RD63_HUMAN,tr|D6RFN0|D6RFN0_HUMAN,tr|D6RAX7|D6RAX7_HUMAN" 4 1280.7089 1.04 45855 11468 3 1280.712213 427.9102 COP9 signalosome complex subunit 4 OS=Homo sapiens OX=9606 GN=COPS4 PE=1 SV=1 6.79 2324.4 - 789657 - - - 2.6251 - 2.134 0.304 - 130.9 1 2 0 0.0034 12 0 0 0 5.87E+06 5.62E+06 - - - 4.0294 0.9955 221125_WJC_METTL3_EV_vs_WT_F04.11469.11469.2 0.11 16-Aug R.NQAIEELEK[136.11].S "sp|Q9P289|STK26_HUMAN,tr|B4E0Y9|B4E0Y9_HUMAN,tr|Q8NBY1|Q8NBY1_HUMAN" 3 1080.5543 0.59 45856 11469 2 1080.553175 541.2844 Serine\threonine-protein kinase 26 OS=Homo sapiens OX=9606 GN=STK26 PE=1 SV=2 4.25 2324.5 - 668941 - - - -0.9986 - 1.445 0.163 - 229.6 1 2 0 -0.0011 9 0 0 0 5.64E+06 9.60E+06 - - - 1.3095 0.9999 221125_WJC_METTL3_EV_vs_WT_F04.11470.11470.3 0.000141 14/40 K.NFYVEHPEVAR.L "sp|Q92841|DDX17_HUMAN,tr|A0A5H1ZRQ2|A0A5H1ZRQ2_HUMAN,tr|A0A1X7SBZ2|A0A1X7SBZ2_HUMAN" 3 1359.6571 1.08 45857 11470 3 1359.660356 454.2263 Probable ATP-dependent RNA helicase DDX17 OS=Homo sapiens OX=9606 GN=DDX17 PE=1 SV=2 5.4 2324.7 - 475006 - - - 2.3587 - 2.6 0.473 - 322.8 1 2 0 0.0032 11 0 0 0 1.51E+08 1.40E+08 - - - 6.527 0.9999 221125_WJC_METTL3_EV_vs_WT_F04.11483.11483.3 0.223 16/40 R.LSNLALVKPEK.T "sp|O14737|PDCD5_HUMAN,tr|K7EQA1|K7EQA1_HUMAN" 2 1210.7285 1.53 45869 11483 3 1210.728748 404.5835 Programmed cell death protein 5 OS=Homo sapiens OX=9606 GN=PDCD5 PE=1 SV=3 8.59 2326.2 - 1.43E+06 - - - 0.185 - 2.614 0.339 - 236.3 1 2 0 0.0002 11 0 0 0 2.74E+07 1.79E+07 - - - 5.0492 0.9999 221125_WJC_METTL3_EV_vs_WT_F04.11484.11484.3 0.00182 Nov-40 K.NFYVEHPEVAR[166.11].L "sp|Q92841|DDX17_HUMAN,tr|A0A5H1ZRQ2|A0A5H1ZRQ2_HUMAN,tr|A0A1X7SBZ2|A0A1X7SBZ2_HUMAN" 3 1369.6654 1.08 45870 11484 3 1369.666109 457.5624 Probable ATP-dependent RNA helicase DDX17 OS=Homo sapiens OX=9606 GN=DDX17 PE=1 SV=2 5.4 2326.3 - 1.15E+06 - - - 0.5038 - 2.317 0.41 - 196.1 1 2 0 0.0007 11 0 0 0 1.51E+08 1.40E+08 - - - 5.498 0.9986 221125_WJC_METTL3_EV_vs_WT_F04.11485.11485.2 0.00914 16-Jul R.AEDNFNLEK.E "sp|Q86U86|PB1_HUMAN,tr|E7EVG2|E7EVG2_HUMAN" 2 1078.4931 2.2 45871 11485 2 1078.495778 540.2538 Protein polybromo-1 OS=Homo sapiens OX=9606 GN=PBRM1 PE=1 SV=1 4.14 2326.4 - 1.07E+06 - - - 2.4794 - 1.639 0.366 - 166.3 1 2 0 0.0027 9 0 0 0 1.46E+07 6.66E+06 - - - 3.1729 0.9997 221125_WJC_METTL3_EV_vs_WT_F04.11486.11486.2 0.0308 13/26 K.LAQAAQSSVATITR[166.11].L sp|Q9Y490|TLN1_HUMAN 1 1425.7815 1.11 45872 11486 2 1425.78342 713.898 Talin-1 OS=Homo sapiens OX=9606 GN=TLN1 PE=1 SV=3 9.75 2326.5 - 495492 - - - 1.3382 - 2.538 0.405 - 590.5 1 2 0 0.0019 14 0 0 0 5.32E+06 4.82E+06 - - - 4.369 0.9801 221125_WJC_METTL3_EV_vs_WT_F04.11487.11487.2 0.0809 14-Sep K.DFQKDFVK.Y "sp|P78347|GTF2I_HUMAN,tr|C9J6M0|C9J6M0_HUMAN,tr|A0A494C1K3|A0A494C1K3_HUMAN" 3 1025.5182 1.06 45873 11487 2 1025.518851 513.7664 General transcription factor II-I OS=Homo sapiens OX=9606 GN=GTF2I PE=1 SV=2 5.96 2326.6 - 472435 - - - 0.6387 - 1.432 0.251 - 303.8 1 2 1 0.0007 8 0 0 0 3.78E+06 3.58E+06 - - - 1.9776 0.9886 221125_WJC_METTL3_EV_vs_WT_F04.11490.11490.3 0.0114 Sep-52 K.LAQAAQSSVATITR.L sp|Q9Y490|TLN1_HUMAN 1 1415.7732 0.7 45876 11490 3 1415.77841 472.9317 Talin-1 OS=Homo sapiens OX=9606 GN=TLN1 PE=1 SV=3 9.75 2327 - 289200 - - - 3.6503 - 1.845 0.243 - 115.4 1 2 0 0.0052 14 0 0 0 5.94E+06 8.49E+06 - - - 2.8755 0.9995 221125_WJC_METTL3_EV_vs_WT_F04.11491.11491.2 0.00141 16-Aug R.EYQTQLIQR.V "sp|Q14204|DYHC1_HUMAN,tr|A0A7P0T8N2|A0A7P0T8N2_HUMAN,tr|A0A7P0T9C4|A0A7P0T9C4_HUMAN,tr|A0A7P0TBJ7|A0A7P0TBJ7_HUMAN,tr|A0A804HHY6|A0A804HHY6_HUMAN,tr|A0A7P0T9K2|A0A7P0T9K2_HUMAN,tr|A0A7P0TB64|A0A7P0TB64_HUMAN,tr|A0A2R8Y706|A0A2R8Y706_HUMAN,tr|A0A7P0T916|A0A7P0T916_HUMAN,tr|A0A7P0TB75|A0A7P0TB75_HUMAN,tr|A0A7P0T8W5|A0A7P0T8W5_HUMAN,tr|A0A7P0T9S3|A0A7P0T9S3_HUMAN,tr|A0A7P0TAF3|A0A7P0TAF3_HUMAN,tr|A0A7P0T9F1|A0A7P0T9F1_HUMAN,tr|A0A7P0TAW9|A0A7P0TAW9_HUMAN,tr|A0A2R8YGC7|A0A2R8YGC7_HUMAN,tr|A0A7P0TA13|A0A7P0TA13_HUMAN,tr|A0A7P0T934|A0A7P0T934_HUMAN,tr|A0A7P0TAV5|A0A7P0TAV5_HUMAN,tr|A0A7P0T9Y3|A0A7P0T9Y3_HUMAN,tr|A0A7P0T7V5|A0A7P0T7V5_HUMAN,tr|A0A7P0T9R4|A0A7P0T9R4_HUMAN,tr|A0A2R8Y5T0|A0A2R8Y5T0_HUMAN,tr|A0A7P0T990|A0A7P0T990_HUMAN,tr|A0A7P0T942|A0A7P0T942_HUMAN,tr|A0A2R8YFZ7|A0A2R8YFZ7_HUMAN,tr|A0A7P0T825|A0A7P0T825_HUMAN,tr|A0A2R8Y6H2|A0A2R8Y6H2_HUMAN,tr|A0A7P0TBC9|A0A7P0TBC9_HUMAN,tr|A0A7P0TAM4|A0A7P0TAM4_HUMAN" 30 1177.6091 0.78 45877 11491 2 1177.607928 589.8118 Cytoplasmic dynein 1 heavy chain 1 OS=Homo sapiens OX=9606 GN=DYNC1H1 PE=1 SV=5 6.1 2327.1 - 197044 - - - -1.0267 - 1.741 0.36 - 385.9 1 2 0 -0.0012 9 0 0 0 1.24E+07 1.58E+07 - - - 3.3037 0.9994 221125_WJC_METTL3_EV_vs_WT_F04.11497.11497.2 0.0227 16-Jul K.IQQQFSDLK.R sp|O94906|PRP6_HUMAN 1 1105.5768 0.36 45881 11497 2 1105.57677 553.7957 Pre-mRNA-processing factor 6 OS=Homo sapiens OX=9606 GN=PRPF6 PE=1 SV=1 5.84 2327.8 - 2.77E+06 - - - -0.0036 - 1.692 0.315 - 148.4 1 2 0 0 9 0 0 0 2.36E+07 6.49E+07 - - - 2.8891 0.972 221125_WJC_METTL3_EV_vs_WT_F04.11498.11498.3 0.777 Sep-36 R.IDISPSTLR[166.11]K[136.11].H "sp|Q9NYF8|BCLF1_HUMAN,tr|E9PKI6|E9PKI6_HUMAN,tr|A0A1W2PQ43|A0A1W2PQ43_HUMAN,tr|E9PK91|E9PK91_HUMAN,tr|E9PK09|E9PK09_HUMAN,tr|E9PQN2|E9PQN2_HUMAN" 6 1146.6727 0.001 45882 11498 3 1146.673595 383.2315 Bcl-2-associated transcription factor 1 OS=Homo sapiens OX=9606 GN=BCLAF1 PE=1 SV=2 8.75 2327.8 - 2.16E+06 - - - 0.743 - 1.624 0.111 - 86.4 1 2 0 0.0009 10 0 0 0 0.00E+00 1.63E+07 - - - 1.1934 0.9995 221125_WJC_METTL3_EV_vs_WT_F04.11501.11501.2 6.04E-05 24-Dec R.ATAGAYIASQTVK[136.11].K "sp|P28074|PSB5_HUMAN,tr|H0YJM8|H0YJM8_HUMAN" 2 1287.6914 0.57 45885 11501 2 1287.692746 644.853 Proteasome subunit beta type-5 OS=Homo sapiens OX=9606 GN=PSMB5 PE=1 SV=3 8.63 2328.2 - 372497 - - - 1.0329 - 2.257 0.297 - 535.7 1 2 0 0.0013 13 0 0 0 1.27E+07 2.24E+07 - - - 3.3235 0.9751 221125_WJC_METTL3_EV_vs_WT_F04.11502.11502.2 0.266 14-Jul K.TLNEWDSR.H sp|O15371|EIF3D_HUMAN 1 1019.4672 1.14 45886 11502 2 1019.470201 510.7409 Eukaryotic translation initiation factor 3 subunit D OS=Homo sapiens OX=9606 GN=EIF3D PE=1 SV=1 4.37 2328.3 - 422146 - - - 2.9211 - 1.131 0.214 - 192.2 1 2 0 0.003 8 0 0 0 3.53E+06 3.08E+06 - - - 0.9919 0.9993 221125_WJC_METTL3_EV_vs_WT_F04.11506.11506.2 0.0162 14-Oct K.ILEVHIDK[136.11].G sp|P31689|DNJA1_HUMAN 1 973.5688 0.5 45888 11506 2 973.57061 487.7917 DnaJ homolog subfamily A member 1 OS=Homo sapiens OX=9606 GN=DNAJA1 PE=1 SV=2 5.32 2328.9 - 721497 - - - 1.8776 - 1.845 0.351 - 223.5 1 2 0 0.0018 8 0 0 0 4.41E+06 8.87E+06 - - - 3.4801 0.9999 221125_WJC_METTL3_EV_vs_WT_F04.11508.11508.2 0.00146 22-Nov K.DPVSAAVPAPGR.N sp|Q68EM7|RHG17_HUMAN 1 1135.5986 1.91 45890 11508 2 1135.599491 568.8066 Rho GTPase-activating protein 17 OS=Homo sapiens OX=9606 GN=ARHGAP17 PE=1 SV=1 5.84 2329.1 - 597796 - - - 0.8093 - 2.541 0.481 - 370 1 2 0 0.0009 12 0 0 0 2.15E+07 1.13E+07 - - - 5.0471 0.9989 221125_WJC_METTL3_EV_vs_WT_F04.11509.11509.3 0.00962 Dec-48 R.VPSHLQAETLVGK.V sp|Q08554|DSC1_HUMAN 1 1377.7616 44.56 45891 11509 3 1377.764872 460.2611 Desmocollin-1 OS=Homo sapiens OX=9606 GN=DSC1 PE=1 SV=2 6.72 2329.2 - 478050 - - - 2.364 - 2.077 0.301 - 196.6 1 2 0 0.0033 13 0 0 0 5.18E+06 1.16E+05 - - - 3.8767 0.9726 221125_WJC_METTL3_EV_vs_WT_F04.11510.11510.2 1.39 14-Sep R.TR[166.11]LEILEK[136.11].G sp|Q8N0X7|SPART_HUMAN 1 1018.6142 0.99 45892 11510 2 1018.614369 510.3144 Spartin OS=Homo sapiens OX=9606 GN=SPART PE=1 SV=1 5.81 2329.4 - 476152 - - - 0.1993 - 1.906 0.087 - 441.2 1 2 1 0.0002 8 0 0 0 1.52E+07 1.53E+07 - - - 1.6288 1 221125_WJC_METTL3_EV_vs_WT_F04.11519.11519.3 4.96E-08 15/64 R.VMLGETNPADSK[136.11]PGTIR[166.11].G "sp|O60361|NDK8_HUMAN,sp|P15531|NDKA_HUMAN,sp|P22392|NDKB_HUMAN,tr|Q32Q12|Q32Q12_HUMAN,tr|Q32Q12|Q32Q12_HUMAN,tr|J3KPD9|J3KPD9_HUMAN,tr|E7ERL0|E7ERL0_HUMAN" 7 1802.9316 1.51 45900 11519 3 1802.93566 601.9845 Putative nucleoside diphosphate kinase OS=Homo sapiens OX=9606 GN=NME2P1 PE=5 SV=1 6.04 2330.6 - 2.24E+06 - - - 2.2774 - 3.024 0.598 - 252.7 1 2 0 0.0041 17 0 0 0 2.32E+08 1.53E+08 - - - 8.0015 0.9966 221125_WJC_METTL3_EV_vs_WT_F04.11521.11521.2 0.0259 16-Aug R.EQQDLEFAK[136.11].E sp|O43242|PSMD3_HUMAN 1 1114.5386 0.42 45901 11521 2 1114.541695 558.2766 26S proteasome non-ATPase regulatory subunit 3 OS=Homo sapiens OX=9606 GN=PSMD3 PE=1 SV=2 4.14 2330.8 - 2.33E+06 - - - 2.7733 - 1.567 0.29 - 267.1 1 2 0 0.0031 9 0 0 0 9.80E+06 2.35E+07 - - - 2.4814 0.9981 221125_WJC_METTL3_EV_vs_WT_F04.11522.11522.2 3.50E-06 18-Oct K.YSQNIYIQNR.N sp|Q99959|PKP2_HUMAN 1 1297.6415 1.15 45902 11522 2 1297.648307 649.828 Plakophilin-2 OS=Homo sapiens OX=9606 GN=PKP2 PE=1 SV=2 8.59 2330.9 - 1.00E+06 - - - 5.2464 - 2.279 0.591 - 361.9 1 2 0 0.0068 10 0 0 0 8.65E+06 7.53E+06 - - - 5.7033 0.9465 221125_WJC_METTL3_EV_vs_WT_F04.11523.11523.3 1.15 Sep-44 R.ISTMRPLATAYK.A sp|Q8NFH5|NUP35_HUMAN 1 1350.733 1.86 45903 11523 3 1350.733112 451.2516 Nucleoporin NUP35 OS=Homo sapiens OX=9606 GN=NUP35 PE=1 SV=1 9.99 2331 - 732459 - - - 0.1148 - 1.589 0.089 - 86.7 1 2 0 0.0002 12 0 0 0 1.44E+07 7.73E+06 - - - 0.8159 0.9997 221125_WJC_METTL3_EV_vs_WT_F04.11525.11525.3 0.000847 Dec-44 R.IGTNLPLKPC[160.03]AR.A "sp|Q9H019|MFR1L_HUMAN,tr|E9PRK5|E9PRK5_HUMAN,tr|E9PSD6|E9PSD6_HUMAN,tr|E9PRW1|E9PRW1_HUMAN,tr|C9JF50|C9JF50_HUMAN,tr|E9PLU1|E9PLU1_HUMAN" 6 1338.7442 1.97 45905 11525 3 1338.746677 447.2553 Mitochondrial fission regulator 1-like OS=Homo sapiens OX=9606 GN=MTFR1L PE=1 SV=2 9.51 2331.2 - 363040 - - - 1.857 - 2.211 0.345 - 205.8 1 2 0 0.0025 12 0 0 0 1.64E+07 8.32E+06 - - - 4.585 0.9991 221125_WJC_METTL3_EV_vs_WT_F04.11526.11526.3 0.0271 Nov-44 K.TLLHLGSSAPGK.E "sp|Q5SW79|CE170_HUMAN,tr|H0Y2V6|H0Y2V6_HUMAN" 2 1179.6612 1.35 45906 11526 3 1179.661213 394.2277 Centrosomal protein of 170 kDa OS=Homo sapiens OX=9606 GN=CEP170 PE=1 SV=1 8.44 2331.3 - 242268 - - - 0.0348 - 1.67 0.304 - 120.4 1 2 0 0 12 0 0 0 4.43E+06 3.29E+06 - - - 3.3508 0.9939 221125_WJC_METTL3_EV_vs_WT_F04.11527.11527.3 0.123 Nov-36 K.LENSIIPVHK[136.11].Q "sp|Q9UPT5|EXOC7_HUMAN,tr|A0A0A0MSB8|A0A0A0MSB8_HUMAN,tr|K7ERQ5|K7ERQ5_HUMAN,tr|B5MCY9|B5MCY9_HUMAN,tr|B4DJ07|B4DJ07_HUMAN,tr|A0A0A0MRE1|A0A0A0MRE1_HUMAN,tr|C9JME6|C9JME6_HUMAN" 7 1156.6696 0.68 45907 11527 3 1156.66937 386.5638 Exocyst complex component 7 OS=Homo sapiens OX=9606 GN=EXOC7 PE=1 SV=3 6.75 2331.5 - 232325 - - - -0.1634 - 1.575 0.201 - 95.5 1 2 0 -0.0002 10 0 0 0 1.65E+06 2.42E+06 - - - 2.1075 0.9992 221125_WJC_METTL3_EV_vs_WT_F04.11530.11530.2 0.000246 22-Sep R.ETQETLALTQGK[136.11].L "sp|Q13136|LIPA1_HUMAN,tr|E9PPF6|E9PPF6_HUMAN,tr|A0A3B3ITS2|A0A3B3ITS2_HUMAN,tr|E9PJZ7|E9PJZ7_HUMAN,tr|E9PID5|E9PID5_HUMAN,tr|A0A2R8Y7R9|A0A2R8Y7R9_HUMAN" 6 1325.6918 0.63 45910 11530 2 1325.695521 663.8532 Liprin-alpha-1 OS=Homo sapiens OX=9606 GN=PPFIA1 PE=1 SV=1 4.53 2331.9 - 155381 - - - 2.7993 - 1.914 0.447 - 354.4 1 2 0 0.0037 12 0 0 0 1.94E+06 3.09E+06 - - - 4.0495 0.9958 221125_WJC_METTL3_EV_vs_WT_F04.11533.11533.2 0.0191 28-Oct K.EVAETSAGPSVVSVK.T sp|P13196|HEM1_HUMAN 1 1458.7566 3 45913 11533 2 1458.760321 730.3856 "5-aminolevulinate synthase, nonspecific, mitochondrial OS=Homo sapiens OX=9606 GN=ALAS1 PE=1 SV=2" 4.53 2332.2 - 99276.6 - - - 2.5583 - 1.404 0.311 - 206 1 2 0 0.0037 15 0 0 0 4.81E+05 1.60E+05 - - - 2.1711 0.9998 221125_WJC_METTL3_EV_vs_WT_F04.11535.11535.2 1.5 18-Nov R.TGIDLGTTGR.L "sp|Q14498|RBM39_HUMAN,tr|A0A0U1RQW2|A0A0U1RQW2_HUMAN,tr|H0Y4X3|H0Y4X3_HUMAN,tr|A0A0U1RQH7|A0A0U1RQH7_HUMAN,tr|A0A087X122|A0A087X122_HUMAN,tr|G3XAC6|G3XAC6_HUMAN" 6 989.5142 1.09 45914 11535 2 989.515699 495.7644 RNA-binding protein 39 OS=Homo sapiens OX=9606 GN=RBM39 PE=1 SV=2 5.5 2332.5 - 3.97E+06 - - - 1.5412 - 2.471 0.437 - 377.9 1 2 0 0.0015 10 0 0 0 5.00E+07 4.59E+07 - - - 4.7933 0.9967 221125_WJC_METTL3_EV_vs_WT_F04.11537.11537.2 0.0618 18-Oct K.HLLIGVSSDR[166.11].G sp|P36542|ATPG_HUMAN 1 1105.6119 1.58 45915 11537 2 1105.614329 553.8132 "ATP synthase subunit gamma, mitochondrial OS=Homo sapiens OX=9606 GN=ATP5F1C PE=1 SV=1" 6.74 2332.7 - 2.36E+06 - - - 2.1726 - 2.102 0.143 - 410.4 1 2 0 0.0024 10 0 0 0 9.88E+07 6.25E+07 - - - 2.1701 0.9999 221125_WJC_METTL3_EV_vs_WT_F04.11538.11538.2 3.47E-06 16-Oct R.LEC[160.03]LLNNNK[136.11].N "sp|P61962|DCAF7_HUMAN,tr|A0A087WWI6|A0A087WWI6_HUMAN" 2 1124.5739 1.28 45916 11538 2 1124.574975 563.2942 DDB1- and CUL4-associated factor 7 OS=Homo sapiens OX=9606 GN=DCAF7 PE=1 SV=1 5.99 2332.8 - 1.26E+06 - - - 0.9168 - 2.079 0.52 - 345.8 1 2 0 0.001 9 0 0 0 3.70E+07 2.88E+07 - - - 4.9988 0.997 221125_WJC_METTL3_EV_vs_WT_F04.11539.11539.2 0.00309 22-Oct K.AISSTEAVLNNR.F "sp|Q5T8P6|RBM26_HUMAN,sp|Q9P2N5|RBM27_HUMAN,tr|U3KPZ7|U3KPZ7_HUMAN,tr|A0A087X0H9|A0A087X0H9_HUMAN" 4 1273.6626 1.03 45917 11539 2 1273.668766 637.8386 RNA-binding protein 26 OS=Homo sapiens OX=9606 GN=RBM26 PE=1 SV=3 6.05 2332.8 - 942523 - - - 4.8184 - 2.355 0.406 - 323.6 1 2 0 0.0061 12 0 0 0 1.74E+07 1.70E+07 - - - 4.2915 1 221125_WJC_METTL3_EV_vs_WT_F04.11540.11540.2 3.69E-05 14/22 R.GPDNSMGFGAER[166.11].K "sp|O75534|CSDE1_HUMAN,tr|E9PLT0|E9PLT0_HUMAN" 2 1246.5276 0.46 45918 11540 2 1246.529916 624.2711 Cold shock domain-containing protein E1 OS=Homo sapiens OX=9606 GN=CSDE1 PE=1 SV=2 4.37 2332.9 - 742157 - - - 1.854 - 2.533 0.592 - 924.1 1 2 0 0.0023 12 0 0 0 6.22E+06 1.35E+07 - - - 5.8582 0.997 221125_WJC_METTL3_EV_vs_WT_F04.11541.11541.2 0.111 14-Aug K.ILEVHIDK.G sp|P31689|DNJA1_HUMAN 1 965.5546 0.5 45919 11541 2 965.556361 483.7846 DnaJ homolog subfamily A member 1 OS=Homo sapiens OX=9606 GN=DNAJA1 PE=1 SV=2 5.32 2333.1 - 417035 - - - 1.8425 - 1.574 0.225 - 148.6 1 2 0 0.0018 8 0 0 0 4.41E+06 8.87E+06 - - - 2.0704 0.9984 221125_WJC_METTL3_EV_vs_WT_F04.11545.11545.2 0.0348 20-May K.MSPPPSGFGER[166.11].S "tr|K7EQG2|K7EQG2_HUMAN,tr|E9PAU2|E9PAU2_HUMAN,tr|A0A087WZ13|A0A087WZ13_HUMAN" 3 1170.5367 0.77 45923 11545 2 1170.537307 586.2756 Uncharacterized protein (Fragment) OS=Homo sapiens OX=9606 PE=1 SV=1 5.75 2333.6 - 193566 - - - 0.5075 - 1.288 0.313 - 73.6 1 2 0 0.0006 11 0 0 0 1.80E+06 2.34E+06 - - - 2.0373 0.9999 221125_WJC_METTL3_EV_vs_WT_F04.11546.11546.3 1.80E-06 Dec-52 R.LSHANSAVVLSAVK.V "sp|P63010|AP2B1_HUMAN,sp|Q10567|AP1B1_HUMAN,tr|A0A087WZQ6|A0A087WZQ6_HUMAN,tr|A0A087X253|A0A087X253_HUMAN,tr|C9J1E7|C9J1E7_HUMAN,tr|A0A087WU93|A0A087WU93_HUMAN,tr|A0A087WYD1|A0A087WYD1_HUMAN" 7 1394.7882 1.22 45924 11546 3 1394.790426 465.9367 AP-2 complex subunit beta OS=Homo sapiens OX=9606 GN=AP2B1 PE=1 SV=1 8.76 2333.7 - 140833 - - - 1.6218 - 2.503 0.453 - 146.1 1 2 0 0.0023 14 0 0 0 7.63E+06 6.25E+06 - - - 6.0281 0.9994 221125_WJC_METTL3_EV_vs_WT_F04.11549.11549.2 0.02 18-Aug K.SGIQPLC[160.03]PER[166.11].S sp|P42166|LAP2A_HUMAN 1 1165.5789 0.3 45926 11549 2 1165.579429 583.7967 "Lamina-associated polypeptide 2, isoform alpha OS=Homo sapiens OX=9606 GN=TMPO PE=1 SV=2" 5.72 2334.1 - 330723 - - - 0.4427 - 1.576 0.342 - 150.4 1 2 0 0.0005 10 0 0 0 4.68E+06 1.55E+07 - - - 2.8366 0.9972 221125_WJC_METTL3_EV_vs_WT_F04.11550.11550.2 2.48E-05 24-Oct K.YPPVTPSPPC[160.03]QPK.C "sp|P22532|SPR2D_HUMAN,sp|P35325|SPR2B_HUMAN" 2 1466.7228 6.58 45927 11550 2 1466.715682 734.3687 Small proline-rich protein 2D OS=Homo sapiens OX=9606 GN=SPRR2D PE=2 SV=2 8.2 2334.2 - 142748 - - - -4.8441 - 1.841 0.511 - 336.7 1 2 0 -0.0071 13 0 0 0 3.01E+06 4.58E+05 - - - 4.3794 0.9974 221125_WJC_METTL3_EV_vs_WT_F04.11551.11551.2 0.0146 20-Jul K.TTQFSC[160.03]TLGEK.F "sp|Q01469|FABP5_HUMAN,tr|I6L8B7|I6L8B7_HUMAN" 2 1270.5864 999 45928 11551 2 1270.590025 636.3005 Fatty acid-binding protein 5 OS=Homo sapiens OX=9606 GN=FABP5 PE=1 SV=3 5.66 2334.3 - 1.96E+06 - - - 2.89 - 1.583 0.344 - 170.9 1 2 0 0.0037 11 0 0 0 2.02E+07 0.00E+00 - - - 2.8232 0.9993 221125_WJC_METTL3_EV_vs_WT_F04.11553.11553.2 0.018 22-Oct R.GPDNSMGFGAER.K "sp|O75534|CSDE1_HUMAN,tr|E9PLT0|E9PLT0_HUMAN" 2 1236.5193 0.42 45930 11553 2 1236.523306 619.2669 Cold shock domain-containing protein E1 OS=Homo sapiens OX=9606 GN=CSDE1 PE=1 SV=2 4.37 2334.5 - 631930 - - - 3.2114 - 2.171 0.482 - 290.1 1 2 0 0.004 12 0 0 0 6.22E+06 1.48E+07 - - - 4.6395 0.9997 221125_WJC_METTL3_EV_vs_WT_F04.11557.11557.2 0.00387 16-Sep R.GFELSSSTR.K "sp|O00443|P3C2A_HUMAN,tr|A0A0C4DGF9|A0A0C4DGF9_HUMAN,tr|E9PPP3|E9PPP3_HUMAN" 3 982.472 1.32 45934 11557 2 982.473668 492.2433 Phosphatidylinositol 4-phosphate 3-kinase C2 domain-containing subunit alpha OS=Homo sapiens OX=9606 GN=PIK3C2A PE=1 SV=2 6 2335 - 208440 - - - 1.7242 - 1.958 0.45 - 322.1 1 2 0 0.0017 9 0 0 0 3.24E+07 2.45E+07 - - - 4.3081 0.9977 221125_WJC_METTL3_EV_vs_WT_F04.11558.11558.2 0.00102 24-Aug R.VAQPGPLEPEEPR.A "sp|Q96HY6|DDRGK_HUMAN,tr|A0A0A0MRX2|A0A0A0MRX2_HUMAN" 2 1417.7201 9.62 45935 11558 2 1417.724926 709.8673 DDRGK domain-containing protein 1 OS=Homo sapiens OX=9606 GN=DDRGK1 PE=1 SV=2 4.25 2335.2 - 147934 - - - 3.373 - 1.758 0.379 - 232.9 1 2 0 0.0048 13 0 0 0 1.40E+07 1.45E+06 - - - 3.2868 1 221125_WJC_METTL3_EV_vs_WT_F04.11563.11563.3 1.26E-09 20/64 R.VMLGETNPADSKPGTIR.G "sp|O60361|NDK8_HUMAN,sp|P15531|NDKA_HUMAN,sp|P22392|NDKB_HUMAN,tr|Q32Q12|Q32Q12_HUMAN,tr|Q32Q12|Q32Q12_HUMAN,tr|J3KPD9|J3KPD9_HUMAN,tr|E7ERL0|E7ERL0_HUMAN" 7 1784.9091 1.51 45938 11563 3 1784.912862 595.977 Putative nucleoside diphosphate kinase OS=Homo sapiens OX=9606 GN=NME2P1 PE=5 SV=1 6.04 2335.9 - 9.90E+06 - - - 2.1166 - 3.441 0.651 - 485.5 1 2 0 0.0038 17 0 0 0 2.32E+08 1.53E+08 - - - 8.9189 0.9999 221125_WJC_METTL3_EV_vs_WT_F04.11570.11570.3 4.34E-05 16/52 R.LSHANSAVVLSAVK[136.11].V "sp|P63010|AP2B1_HUMAN,sp|Q10567|AP1B1_HUMAN,tr|A0A087WZQ6|A0A087WZQ6_HUMAN,tr|A0A087X253|A0A087X253_HUMAN,tr|C9J1E7|C9J1E7_HUMAN,tr|A0A087WU93|A0A087WU93_HUMAN,tr|A0A087WYD1|A0A087WYD1_HUMAN" 7 1402.8024 1.22 45945 11570 3 1402.806452 468.6081 AP-2 complex subunit beta OS=Homo sapiens OX=9606 GN=AP2B1 PE=1 SV=1 8.76 2336.7 - 394673 - - - 2.9142 - 2.799 0.47 - 444.9 1 2 0 0.0041 14 0 0 0 7.63E+06 6.25E+06 - - - 6.5142 0.9999 221125_WJC_METTL3_EV_vs_WT_F04.11573.11573.3 0.000237 Dec-36 R.SPVFNHSLYR.T "sp|Q96RN5|MED15_HUMAN,tr|G3V1P5|G3V1P5_HUMAN" 2 1218.6146 2.78 45948 11573 3 1218.614918 407.2121 Mediator of RNA polymerase II transcription subunit 15 OS=Homo sapiens OX=9606 GN=MED15 PE=1 SV=2 8.49 2337.1 - 276486 - - - 0.2971 - 2.534 0.375 - 257.4 1 2 0 0.0004 10 0 0 0 2.38E+07 8.57E+06 - - - 5.4362 0.9989 221125_WJC_METTL3_EV_vs_WT_F04.11574.11574.2 0.0497 18-Jul K.SGIQPLC[160.03]PER.S sp|P42166|LAP2A_HUMAN 1 1155.5706 0.33 45949 11574 2 1155.569552 578.7926 "Lamina-associated polypeptide 2, isoform alpha OS=Homo sapiens OX=9606 GN=TMPO PE=1 SV=2" 5.72 2337.2 - 273339 - - - -0.9441 - 1.256 0.375 - 119.5 1 2 0 -0.0011 10 0 0 0 3.33E+06 9.98E+06 - - - 2.4466 0.9976 221125_WJC_METTL3_EV_vs_WT_F04.11575.11575.3 7.82E-06 Nov-36 K.YGNIDAVHLK[136.11].A "sp|P23378|GCSP_HUMAN,tr|A0A1W2PQV3|A0A1W2PQV3_HUMAN,tr|A0A1W2PQU6|A0A1W2PQU6_HUMAN,tr|A0A1W2PP74|A0A1W2PP74_HUMAN" 4 1136.607 0.001 45950 11575 3 1137.611394 379.8763 "Glycine dehydrogenase (decarboxylating), mitochondrial OS=Homo sapiens OX=9606 GN=GLDC PE=1 SV=2" 6.74 2337.3 - 103518 - - - 883.7145 - 1.852 0.483 - 101.5 1 2 0 1.0044 10 0 0 0 0.00E+00 2.82E+05 - - - 5.4465 0.9998 221125_WJC_METTL3_EV_vs_WT_F04.11576.11576.2 2.24E-07 Aug-32 R.VMLGETNPADSK[136.11]PGTIR[166.11].G "sp|O60361|NDK8_HUMAN,sp|P15531|NDKA_HUMAN,sp|P22392|NDKB_HUMAN,tr|Q32Q12|Q32Q12_HUMAN,tr|Q32Q12|Q32Q12_HUMAN,tr|J3KPD9|J3KPD9_HUMAN,tr|E7ERL0|E7ERL0_HUMAN" 7 1802.9316 1.64 45951 11576 2 1802.933577 902.4731 Putative nucleoside diphosphate kinase OS=Homo sapiens OX=9606 GN=NME2P1 PE=5 SV=1 6.04 2337.5 - 96827.6 - - - 1.1221 - 2.066 0.565 - 135 1 2 0 0.002 17 0 0 0 3.78E+06 2.31E+06 - - - 4.9974 0.9991 221125_WJC_METTL3_EV_vs_WT_F04.11582.11582.2 0.221 16-Sep K.LASLEELKR.Q sp|P15924|DESP_HUMAN 1 1057.6132 91.17 45955 11582 2 1057.613362 529.8139 Desmoplakin OS=Homo sapiens OX=9606 GN=DSP PE=1 SV=3 6.14 2338.1 - 602369 - - - 0.1919 - 2.061 0.178 - 314.4 1 2 0 0.0002 9 0 0 0 1.05E+07 1.15E+05 - - - 2.4479 0.9985 221125_WJC_METTL3_EV_vs_WT_F04.11583.11583.2 0.00478 16-Aug K.EQYNMLGGK.Y sp|Q02413|DSG1_HUMAN 1 1038.4804 13.52 45956 11583 2 1038.482247 520.2475 Desmoglein-1 OS=Homo sapiens OX=9606 GN=DSG1 PE=1 SV=2 6.1 2338.2 - 430625 - - - 1.7487 - 1.394 0.351 - 220.9 1 2 0 0.0018 9 0 0 0 2.86E+07 2.12E+06 - - - 2.5939 1 221125_WJC_METTL3_EV_vs_WT_F04.11584.11584.2 9.61E-06 15/24 M.FSNLASDEQDSVR[166.11].L "sp|P30153|2AAA_HUMAN,tr|C9J9C1|C9J9C1_HUMAN,tr|B3KQV6|B3KQV6_HUMAN" 3 1476.672 0.78 45957 11584 2 1476.667655 739.3433 Serine\threonine-protein phosphatase 2A 65 kDa regulatory subunit A alpha isoform OS=Homo sapiens OX=9606 GN=PPP2R1A PE=1 SV=4 4.03 2338.4 - 334402 - - - -2.9566 - 3.11 0.588 - 883.5 1 1 0 -0.0044 13 0 0 0 3.26E+06 4.16E+06 - - - 6.2946 0.9789 221125_WJC_METTL3_EV_vs_WT_F04.11588.11588.2 0.000723 18-Sep R.SPVFNHSLYR.T "sp|Q96RN5|MED15_HUMAN,tr|G3V1P5|G3V1P5_HUMAN" 2 1218.6146 1.4 45961 11588 2 1218.623132 610.3146 Mediator of RNA polymerase II transcription subunit 15 OS=Homo sapiens OX=9606 GN=MED15 PE=1 SV=2 8.49 2338.9 - 175822 - - - 7.0375 - 1.675 0.418 - 280.4 1 2 0 0.0086 10 0 0 0 3.90E+06 2.78E+06 - - - 3.5654 0.9998 221125_WJC_METTL3_EV_vs_WT_F04.11589.11589.2 1.04E-05 Dec-32 R.VMLGETNPADSKPGTIR.G "sp|O60361|NDK8_HUMAN,sp|P15531|NDKA_HUMAN,sp|P22392|NDKB_HUMAN,tr|Q32Q12|Q32Q12_HUMAN,tr|Q32Q12|Q32Q12_HUMAN,tr|J3KPD9|J3KPD9_HUMAN,tr|E7ERL0|E7ERL0_HUMAN" 7 1784.9091 1.64 45962 11589 2 1784.911854 893.4618 Putative nucleoside diphosphate kinase OS=Homo sapiens OX=9606 GN=NME2P1 PE=5 SV=1 6.04 2339 - 174244 - - - 1.5519 - 2.4 0.542 - 329 1 2 0 0.0028 17 0 0 0 3.78E+06 2.31E+06 - - - 5.1957 0.9866 221125_WJC_METTL3_EV_vs_WT_F04.11590.11590.2 0.0117 14-Jun K.HVDLLINK[136.11].Y "sp|P22307|SCP2_HUMAN,tr|H0YCB0|H0YCB0_HUMAN,tr|E9PLD1|E9PLD1_HUMAN" 3 958.5691 1.62 45963 11590 2 958.568687 480.2918 Sterol carrier protein 2 OS=Homo sapiens OX=9606 GN=SCP2 PE=1 SV=2 6.74 2339.1 - 151879 - - - -0.4475 - 1.527 0.034 - 110.7 2 2 0 -0.0004 8 0 0 0 2.96E+06 1.83E+06 - - - 0.4342 0.9991 221125_WJC_METTL3_EV_vs_WT_F04.11594.11594.3 0.000619 Oct-40 K.LFDSTTLEHQK[136.11].T "sp|Q13347|EIF3I_HUMAN,tr|A0A7I2YQT9|A0A7I2YQT9_HUMAN,tr|A0A7I2V613|A0A7I2V613_HUMAN,tr|A0A7I2V3N2|A0A7I2V3N2_HUMAN,tr|A0A7I2YQU2|A0A7I2YQU2_HUMAN,tr|A0A7I2YQI6|A0A7I2YQI6_HUMAN,tr|A0A7I2YQF8|A0A7I2YQF8_HUMAN,tr|Q5TFK1|Q5TFK1_HUMAN,tr|A0A7I2V3U3|A0A7I2V3U3_HUMAN,tr|A0A7I2V607|A0A7I2V607_HUMAN,tr|A0A7I2V640|A0A7I2V640_HUMAN,tr|A0A7P0MRT9|A0A7P0MRT9_HUMAN,tr|A0A7I2V3K6|A0A7I2V3K6_HUMAN,tr|A0A7I2V4S8|A0A7I2V4S8_HUMAN,tr|A0A7I2V5V8|A0A7I2V5V8_HUMAN,tr|A0A7I2V2M3|A0A7I2V2M3_HUMAN,tr|A0A7I2V4C2|A0A7I2V4C2_HUMAN,tr|A0A7I2YQP9|A0A7I2YQP9_HUMAN,tr|A0A7I2YQI2|A0A7I2YQI2_HUMAN,tr|A0A7I2YQC8|A0A7I2YQC8_HUMAN,tr|A0A7I2V685|A0A7I2V685_HUMAN" 21 1325.6707 1.06 45965 11594 3 1325.673179 442.8975 Eukaryotic translation initiation factor 3 subunit I OS=Homo sapiens OX=9606 GN=EIF3I PE=1 SV=1 5.32 2339.6 - 2.19E+06 - - - 1.8843 - 1.955 0.305 - 100.4 1 2 0 0.0025 11 0 0 0 7.23E+07 6.80E+07 - - - 3.8442 0.9997 221125_WJC_METTL3_EV_vs_WT_F04.11595.11595.2 0.0808 16-Sep R.GFELSSSTR[166.11].K "sp|O00443|P3C2A_HUMAN,tr|A0A0C4DGF9|A0A0C4DGF9_HUMAN,tr|E9PPP3|E9PPP3_HUMAN" 3 992.4802 1.35 45966 11595 2 992.481529 497.2474 Phosphatidylinositol 4-phosphate 3-kinase C2 domain-containing subunit alpha OS=Homo sapiens OX=9606 GN=PIK3C2A PE=1 SV=2 6 2339.7 - 1.88E+06 - - - 1.2947 - 1.919 0.456 - 308.2 1 2 0 0.0013 9 0 0 0 3.19E+07 2.37E+07 - - - 4.2943 0.9996 221125_WJC_METTL3_EV_vs_WT_F04.11596.11596.2 0.000542 18-Oct R.QENGASVILR.D "sp|P29692|EF1D_HUMAN,tr|E9PI39|E9PI39_HUMAN,tr|E9PMW7|E9PMW7_HUMAN,tr|E9PQ49|E9PQ49_HUMAN,tr|A0A087X1X7|A0A087X1X7_HUMAN,tr|E9PL12|E9PL12_HUMAN,tr|E9PK72|E9PK72_HUMAN,tr|H0YCK7|H0YCK7_HUMAN,tr|E9PK06|E9PK06_HUMAN,tr|E9PIZ1|E9PIZ1_HUMAN,tr|E9PPR1|E9PPR1_HUMAN,tr|E9PRY8|E9PRY8_HUMAN,tr|E9PK01|E9PK01_HUMAN" 13 1085.5829 1.53 45967 11596 2 1085.585058 543.7987 Elongation factor 1-delta OS=Homo sapiens OX=9606 GN=EEF1D PE=1 SV=5 6 2339.8 - 1.48E+06 - - - 1.9676 - 2.169 0.417 - 557.5 1 2 0 0.0021 10 0 0 0 3.57E+07 2.33E+07 - - - 4.2815 0.9999 221125_WJC_METTL3_EV_vs_WT_F04.11598.11598.3 0.0036 13/36 R.SPVFNHSLYR[166.11].T "sp|Q96RN5|MED15_HUMAN,tr|G3V1P5|G3V1P5_HUMAN" 2 1228.6228 2.78 45969 11598 3 1228.622177 410.5482 Mediator of RNA polymerase II transcription subunit 15 OS=Homo sapiens OX=9606 GN=MED15 PE=1 SV=2 8.49 2340 - 553863 - - - -0.5282 - 2.678 0.362 - 309.5 1 2 0 -0.0006 10 0 0 0 2.38E+07 8.57E+06 - - - 5.4526 0.9619 221125_WJC_METTL3_EV_vs_WT_F04.11599.11599.2 1.63 18-Aug K.SDDILEEGEK[136.11].N sp|Q7Z2T5|TRM1L_HUMAN 1 1141.523 0.22 45970 11599 2 1141.525673 571.7688 TRMT1-like protein OS=Homo sapiens OX=9606 GN=TRMT1L PE=1 SV=2 3.83 2340.2 - 545001 - - - 2.3302 - 1.201 0.117 - 110.6 1 2 0 0.0027 10 0 0 0 1.85E+06 8.34E+06 - - - 0.4156 0.998 221125_WJC_METTL3_EV_vs_WT_F04.11600.11600.2 3.01E-05 28-Oct R.GGGLGSPGEGGALPR[166.11].C sp|Q7Z7A3|CTU1_HUMAN 1 1290.6556 2.56 45971 11600 2 1290.660516 646.3351 Cytoplasmic tRNA 2-thiolation protein 1 OS=Homo sapiens OX=9606 GN=CTU1 PE=1 SV=1 6 2340.3 - 424096 - - - 3.8221 - 2.02 0.419 - 179.1 1 2 0 0.0049 15 0 0 0 1.25E+07 4.88E+06 - - - 3.8628 0.9971 221125_WJC_METTL3_EV_vs_WT_F04.11601.11601.3 0.003 Dec-40 R.QLESLPATHIR[166.11].G "sp|Q13330|MTA1_HUMAN,tr|E7ESY4|E7ESY4_HUMAN" 2 1273.7018 1.53 45972 11601 3 1273.705872 425.5745 Metastasis-associated protein MTA1 OS=Homo sapiens OX=9606 GN=MTA1 PE=1 SV=2 6.75 2340.4 - 360512 - - - 3.1931 - 2.14 0.262 - 266.2 1 2 0 0.0041 11 0 0 0 1.40E+07 9.18E+06 - - - 3.6212 0.9608 221125_WJC_METTL3_EV_vs_WT_F04.11604.11604.2 1.82 18-Aug R.GINVALANGK.T "sp|Q92520|FAM3C_HUMAN,tr|C9JMN4|C9JMN4_HUMAN,tr|C9JP35|C9JP35_HUMAN" 3 955.5451 0.58 45975 11604 2 955.54712 478.7798 Protein FAM3C OS=Homo sapiens OX=9606 GN=FAM3C PE=1 SV=1 8.75 2340.8 - 255020 - - - 2.1349 - 1.217 0.116 - 107.3 2 2 0 0.002 10 0 0 0 2.12E+06 3.66E+06 - - - 0.3108 0.9998 221125_WJC_METTL3_EV_vs_WT_F04.11609.11609.2 0.00204 18-Aug K.GLSEDVSISK.F "sp|Q15029|U5S1_HUMAN,tr|K7EP67|K7EP67_HUMAN" 2 1033.5292 1.91 45978 11609 2 1033.529227 517.7719 116 kDa U5 small nuclear ribonucleoprotein component OS=Homo sapiens OX=9606 GN=EFTUD2 PE=1 SV=1 4.37 2341.4 - 1.11E+06 - - - 0.0697 - 1.778 0.434 - 152.2 1 2 0 0.0001 10 0 0 0 9.27E+07 4.86E+07 - - - 3.8529 0.9287 221125_WJC_METTL3_EV_vs_WT_F04.11610.11610.2 0.00563 14-Jul R.YPDGIISK[136.11].P sp|Q86U44|MTA70_HUMAN 1 899.4844 0.02 45979 11610 2 899.485427 450.7495 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 5.83 2341.5 - 1.81E+06 - - - 1.1607 - 1.46 0.31 - 127.9 1 1 0 0.001 8 0 0 0 1.64E+06 8.48E+07 - - - 2.4717 0.9997 221125_WJC_METTL3_EV_vs_WT_F04.11612.11612.2 0.0127 18-Oct R.SMEVSTQLAR[166.11].A sp|Q9UQE7|SMC3_HUMAN 1 1130.5629 0.79 45981 11612 2 1130.563255 566.2887 Structural maintenance of chromosomes protein 3 OS=Homo sapiens OX=9606 GN=SMC3 PE=1 SV=2 5.72 2341.8 - 568117 - - - 0.2892 - 1.913 0.381 - 446.6 1 2 0 0.0003 10 0 0 0 5.26E+06 6.63E+06 - - - 3.6656 0.9822 221125_WJC_METTL3_EV_vs_WT_F04.11613.11613.3 0.00547 Nov-40 V.LGR[166.11]PGFSIADK[136.11].K "sp|P62913|RL11_HUMAN,tr|Q5VVC8|Q5VVC8_HUMAN" 2 1177.6574 0.92 45982 11613 3 1177.657515 393.5598 60S ribosomal protein L11 OS=Homo sapiens OX=9606 GN=RPL11 PE=1 SV=2 8.75 2341.9 - 442822 - - - 0.0747 - 2.234 0.347 - 107.6 1 1 0 0.0001 11 0 0 0 7.89E+06 8.53E+06 - - - 4.6921 0.9647 221125_WJC_METTL3_EV_vs_WT_F04.11614.11614.2 1.76 14-Sep R.TRLEILEK.G sp|Q8N0X7|SPART_HUMAN 1 1000.5917 0.99 45983 11614 2 1000.591368 501.3031 Spartin OS=Homo sapiens OX=9606 GN=SPART PE=1 SV=1 5.81 2342 - 405903 - - - -0.3278 - 1.867 0.067 - 288.8 1 2 1 -0.0003 8 0 0 0 1.52E+07 1.53E+07 - - - 1.4187 0.9999 221125_WJC_METTL3_EV_vs_WT_F04.11616.11616.2 0.00132 22-Dec R.DAQELYAAGENR[166.11].L sp|P50995|ANX11_HUMAN 1 1345.6138 2.8 45985 11616 2 1345.614638 673.8142 Annexin A11 OS=Homo sapiens OX=9606 GN=ANXA11 PE=1 SV=1 4.14 2342.3 - 316088 - - - 0.6391 - 2.8 0.528 - 514.5 1 2 0 0.0009 12 0 0 0 1.05E+07 3.75E+06 - - - 5.6496 0.9938 221125_WJC_METTL3_EV_vs_WT_F04.11618.11618.3 0.000382 Aug-36 R.GLDDDRGPWR.N sp|Q14152|EIF3A_HUMAN 1 1185.5527 0.87 45987 11618 3 1185.548711 396.1915 Eukaryotic translation initiation factor 3 subunit A OS=Homo sapiens OX=9606 GN=EIF3A PE=1 SV=1 4.43 2342.5 - 214692 - - - -3.3512 - 1.682 0.379 - 83.5 1 2 1 -0.004 10 0 0 0 6.30E+06 7.20E+06 - - - 4.283 0.8619 221125_WJC_METTL3_EV_vs_WT_F04.11619.11619.2 1.52 18-Jun R.STTPDITGYR.L sp|P02751|FINC_HUMAN 1 1109.5353 0.02 45988 11619 2 1109.533647 555.7749 Fibronectin OS=Homo sapiens OX=9606 GN=FN1 PE=1 SV=5 5.55 2342.6 - 601877 - - - -1.4925 - 0.922 0.045 - 100.8 1 2 0 -0.0017 10 0 0 0 2.13E+06 1.24E+08 - - - -0.8538 0.9896 221125_WJC_METTL3_EV_vs_WT_F04.11620.11620.2 0.32 14-Jun K.TQEPFSVR[166.11].N sp|O60942|MCE1_HUMAN 1 972.4904 0.83 45989 11620 2 972.487511 487.2525 mRNA-capping enzyme OS=Homo sapiens OX=9606 GN=RNGTT PE=1 SV=1 5.66 2342.8 - 139175 - - - -2.9861 - 1.334 0.237 - 143.3 1 2 0 -0.0029 8 0 0 0 1.97E+06 2.37E+06 - - - 1.6597 0.9995 221125_WJC_METTL3_EV_vs_WT_F04.11622.11622.2 0.000168 28-Nov R.GGGLGSPGEGGALPR.C sp|Q7Z7A3|CTU1_HUMAN 1 1280.6473 1.5 45990 11622 2 1280.650445 641.3309 Cytoplasmic tRNA 2-thiolation protein 1 OS=Homo sapiens OX=9606 GN=CTU1 PE=1 SV=1 6 2343 - 456804 - - - 2.4456 - 2.145 0.457 - 258.5 1 2 0 0.0031 15 0 0 0 6.76E+06 4.52E+06 - - - 4.2916 0.9998 221125_WJC_METTL3_EV_vs_WT_F04.11625.11625.2 1.75E-06 26-Dec K.QPPIQSTAGAVPVR.N sp|P55081|MFAP1_HUMAN 1 1419.7834 1.38 45992 11625 2 1419.785329 710.899 Microfibrillar-associated protein 1 OS=Homo sapiens OX=9606 GN=MFAP1 PE=1 SV=2 9.75 2343.3 - 913344 - - - 1.3495 - 2.032 0.512 - 346.3 1 2 0 0.0019 14 0 0 0 1.96E+07 1.42E+07 - - - 4.6013 0.991 221125_WJC_METTL3_EV_vs_WT_F04.11626.11626.2 0.0288 16-Sep R.LQNFSYDQR.E sp|Q9NTZ6|RBM12_HUMAN 1 1169.5465 1.19 45993 11626 2 1169.552131 585.7805 RNA-binding protein 12 OS=Homo sapiens OX=9606 GN=RBM12 PE=1 SV=1 5.84 2343.4 - 943173 - - - 4.7839 - 1.703 0.322 - 295.8 1 2 0 0.0056 9 0 0 0 1.68E+07 1.42E+07 - - - 2.9578 0.9993 221125_WJC_METTL3_EV_vs_WT_F04.11627.11627.2 0.0141 14-Aug R.NEFNLESK[136.11].S "sp|Q15907|RB11B_HUMAN,sp|P62491|RB11A_HUMAN,tr|H3BMH2|H3BMH2_HUMAN,tr|H3BSC1|H3BSC1_HUMAN" 4 987.4753 0.95 45994 11627 2 987.476 494.7449 Ras-related protein Rab-11B OS=Homo sapiens OX=9606 GN=RAB11B PE=1 SV=4 4.53 2343.5 - 618898 - - - 0.7342 - 1.59 0.318 - 349.7 1 2 0 0.0007 8 0 0 0 3.26E+07 3.44E+07 - - - 2.7881 0.9996 221125_WJC_METTL3_EV_vs_WT_F04.11629.11629.2 0.0174 14-Aug R.NEFNLESK.S "sp|Q15907|RB11B_HUMAN,sp|P62491|RB11A_HUMAN,tr|H3BMH2|H3BMH2_HUMAN,tr|H3BSC1|H3BSC1_HUMAN" 4 979.4611 1.19 45996 11629 2 979.461781 490.7378 Ras-related protein Rab-11B OS=Homo sapiens OX=9606 GN=RAB11B PE=1 SV=4 4.53 2343.7 - 530603 - - - 0.7208 - 1.685 0.375 - 271.8 1 2 0 0.0007 8 0 0 0 9.61E+07 8.08E+07 - - - 3.3841 0.9998 221125_WJC_METTL3_EV_vs_WT_F04.11636.11636.2 0.00362 18-Oct K.GLSEDVSISK[136.11].F "sp|Q15029|U5S1_HUMAN,tr|K7EP67|K7EP67_HUMAN" 2 1041.5434 1.91 46001 11636 2 1041.543821 521.779 116 kDa U5 small nuclear ribonucleoprotein component OS=Homo sapiens OX=9606 GN=EFTUD2 PE=1 SV=1 4.37 2344.6 - 3.13E+06 - - - 0.4474 - 2.032 0.411 - 280.9 1 2 0 0.0005 10 0 0 0 9.29E+07 4.86E+07 - - - 4.0556 0.9995 221125_WJC_METTL3_EV_vs_WT_F04.11639.11639.3 0.00275 Sep-36 R.FHTITTSYYR[166.11].G sp|P61026|RAB10_HUMAN 1 1297.6331 1.3 46004 11639 3 1297.633254 433.5516 Ras-related protein Rab-10 OS=Homo sapiens OX=9606 GN=RAB10 PE=1 SV=1 8.6 2344.8 - 1.11E+06 - - - 0.1518 - 1.844 0.319 - 205.5 1 2 0 0.0002 10 0 0 0 3.15E+07 2.43E+07 - - - 3.8836 0.9998 221125_WJC_METTL3_EV_vs_WT_F04.11642.11642.3 0.000227 Dec-52 K.QPPIQSTAGAVPVR.N sp|P55081|MFAP1_HUMAN 1 1419.7834 1.17 46007 11642 3 1419.783345 474.2684 Microfibrillar-associated protein 1 OS=Homo sapiens OX=9606 GN=MFAP1 PE=1 SV=2 9.75 2345.1 - 751900 - - - -0.0479 - 2.237 0.369 - 177.7 1 2 0 -0.0001 14 0 0 0 9.83E+06 8.40E+06 - - - 4.7936 0.9994 221125_WJC_METTL3_EV_vs_WT_F04.11643.11643.2 0.595 14-Sep R.K[136.11]LDELLGK[136.11].D "sp|Q96EX1|SIM12_HUMAN,tr|E5RH51|E5RH51_HUMAN" 2 930.5721 0.92 46008 11643 2 930.571808 466.2933 Small integral membrane protein 12 OS=Homo sapiens OX=9606 GN=SMIM12 PE=1 SV=3 6.07 2345.2 - 635467 - - - -0.2955 - 1.94 0.255 - 291.3 1 2 0 -0.0003 8 0 0 0 7.82E+06 8.47E+06 - - - 2.923 0.9997 221125_WJC_METTL3_EV_vs_WT_F04.11645.11645.3 0.000169 Oct-52 K.FLETESHPSIPPPK.L "sp|Q15643|TRIPB_HUMAN,tr|H0YJ97|H0YJ97_HUMAN" 2 1577.809 1.22 46010 11645 3 1577.810075 526.9436 Thyroid receptor-interacting protein 11 OS=Homo sapiens OX=9606 GN=TRIP11 PE=1 SV=3 5.4 2345.4 - 456596 - - - 0.7073 - 1.627 0.39 - 76.8 1 2 0 0.0011 14 0 0 0 6.33E+06 5.18E+06 - - - 4.1813 0.9998 221125_WJC_METTL3_EV_vs_WT_F04.11648.11648.2 2.97E-05 18-Oct R.NYVPEDEDLK.K "sp|Q8WUD4|CCD12_HUMAN,tr|C9JUN5|C9JUN5_HUMAN,tr|J3KR35|J3KR35_HUMAN,tr|S4R331|S4R331_HUMAN" 4 1220.5561 1.65 46012 11648 2 1220.556764 611.2853 Coiled-coil domain-containing protein 12 OS=Homo sapiens OX=9606 GN=CCDC12 PE=1 SV=1 3.92 2345.9 - 852788 - - - 0.5457 - 1.841 0.487 - 369.2 1 2 0 0.0007 10 0 0 0 1.02E+07 6.14E+06 - - - 4.3413 0.999 221125_WJC_METTL3_EV_vs_WT_F04.11652.11652.3 0.00997 Nov-52 K.FLETESHPSIPPPK[136.11].L "sp|Q15643|TRIPB_HUMAN,tr|H0YJ97|H0YJ97_HUMAN" 2 1585.8232 1.22 46015 11652 3 1585.822732 529.615 Thyroid receptor-interacting protein 11 OS=Homo sapiens OX=9606 GN=TRIP11 PE=1 SV=3 5.4 2346.4 - 699053 - - - -0.2693 - 1.635 0.311 - 92.4 1 2 0 -0.0004 14 0 0 0 6.33E+06 5.18E+06 - - - 3.3138 0.9999 221125_WJC_METTL3_EV_vs_WT_F04.11654.11654.2 0.000148 24-Sep K.MSSEVVDSNPYSR.L "sp|Q9GZZ9|UBA5_HUMAN,tr|E7EWE1|E7EWE1_HUMAN,tr|A0A804HJ86|A0A804HJ86_HUMAN,tr|E7EQ61|E7EQ61_HUMAN" 4 1469.6457 0.7 46017 11654 2 1469.647342 735.8301 Ubiquitin-like modifier-activating enzyme 5 OS=Homo sapiens OX=9606 GN=UBA5 PE=1 SV=1 4.37 2346.6 - 195058 - - - 1.1459 - 2.181 0.585 - 273.8 1 2 0 0.0017 13 0 0 0 2.69E+06 3.85E+06 - - - 5.3626 0.9998 221125_WJC_METTL3_EV_vs_WT_F04.11658.11658.2 7.04E-06 20-Sep K.DQVANSAFVER.L sp|P07900|HS90A_HUMAN 1 1234.5942 0.89 46019 11658 2 1234.592034 618.3044 Heat shock protein HSP 90-alpha OS=Homo sapiens OX=9606 GN=HSP90AA1 PE=1 SV=5 4.37 2347.2 - 1.23E+06 - - - -1.7666 - 2.213 0.494 - 279.7 1 2 0 -0.0022 11 0 0 0 1.69E+08 1.89E+08 - - - 4.8379 0.9837 221125_WJC_METTL3_EV_vs_WT_F04.11659.11659.3 0.126 Sep-36 R.FKDLGEENFK.A "sp|P02768|ALBU_HUMAN,tr|A0A087WWT3|A0A087WWT3_HUMAN,tr|B7WNR0|B7WNR0_HUMAN,tr|H7C013|H7C013_HUMAN,tr|A0A0C4DGB6|A0A0C4DGB6_HUMAN,tr|C9JKR2|C9JKR2_HUMAN" 6 1225.5979 4.27 46020 11659 3 1225.596922 409.5399 Albumin OS=Homo sapiens OX=9606 GN=ALB PE=1 SV=2 4.68 2347.3 - 551881 - - - -0.8004 - 1.721 0.208 - 71.5 1 2 1 -0.001 10 0 0 0 7.11E+06 1.66E+06 - - - 2.4442 0.9945 221125_WJC_METTL3_EV_vs_WT_F04.11660.11660.3 0.000533 13/44 S.K[136.11]LSAMMGAVAEK[136.11].K "sp|Q86U44|MTA70_HUMAN,tr|F5H6D8|F5H6D8_HUMAN,tr|H0YFV6|H0YFV6_HUMAN,tr|B4DTN4|B4DTN4_HUMAN" 4 1250.6698 0.25 46021 11660 3 1250.66967 417.8972 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 8.59 2347.4 - 1.45E+06 - - - -0.076 - 2.583 0.419 - 238.6 1 1 0 -0.0001 12 0 0 0 4.29E+07 1.74E+08 - - - 5.8418 1 221125_WJC_METTL3_EV_vs_WT_F04.11662.11662.2 3.64E-05 13/24 K.MSSEVVDSNPYSR[166.11].L "sp|Q9GZZ9|UBA5_HUMAN,tr|E7EWE1|E7EWE1_HUMAN,tr|A0A804HJ86|A0A804HJ86_HUMAN,tr|E7EQ61|E7EQ61_HUMAN" 4 1479.6539 0.7 46023 11662 2 1479.65211 740.8342 Ubiquitin-like modifier-activating enzyme 5 OS=Homo sapiens OX=9606 GN=UBA5 PE=1 SV=1 4.37 2347.6 - 345530 - - - -1.2287 - 2.772 0.563 - 634.7 1 2 0 -0.0018 13 0 0 0 2.69E+06 3.85E+06 - - - 5.8155 0.9774 221125_WJC_METTL3_EV_vs_WT_F04.11665.11665.2 0.00802 22-Dec K.TSLEASMEASPK[136.11].A "sp|Q8IWC1|MA7D3_HUMAN,tr|A0A0A0MRP0|A0A0A0MRP0_HUMAN" 2 1257.6002 9.29 46026 11665 2 1257.590483 629.8074 MAP7 domain-containing protein 3 OS=Homo sapiens OX=9606 GN=MAP7D3 PE=1 SV=2 4.53 2348 - 310014 - - - -7.7409 - 2.41 0.37 - 696.2 1 2 0 -0.0097 12 0 0 0 5.76E+07 6.20E+06 - - - 4.0852 0.9995 221125_WJC_METTL3_EV_vs_WT_F04.11671.11671.2 0.000153 22-Nov R.ETAEADVASLNR.R "tr|F5H7S3|F5H7S3_HUMAN,tr|H0YKJ4|H0YKJ4_HUMAN,tr|H0YK48|H0YK48_HUMAN,tr|B7Z596|B7Z596_HUMAN,tr|A0A494BZZ2|A0A494BZZ2_HUMAN,tr|H7BYY1|H7BYY1_HUMAN" 6 1274.6103 0.8 46031 11671 2 1274.613739 638.3124 Tropomyosin alpha-1 chain OS=Homo sapiens OX=9606 GN=TPM1 PE=1 SV=2 4.14 2348.8 - 320908 - - - 2.7302 - 2.169 0.487 - 569.4 1 2 0 0.0035 12 0 0 0 1.65E+06 2.07E+06 - - - 4.6741 0.9987 221125_WJC_METTL3_EV_vs_WT_F04.11672.11672.3 0.00113 Aug-36 K.AK[136.11]EFTNVYIK[136.11].N "sp|Q13310|PABP4_HUMAN,sp|P11940|PABP1_HUMAN,tr|A0A7I2V5W9|A0A7I2V5W9_HUMAN,tr|A0A7I2YQE4|A0A7I2YQE4_HUMAN,tr|A0A7I2V649|A0A7I2V649_HUMAN,tr|B1ANR0|B1ANR0_HUMAN,tr|A0A7I2V4L7|A0A7I2V4L7_HUMAN,tr|H0YCC8|H0YCC8_HUMAN,tr|H0YAR2|H0YAR2_HUMAN,tr|E7ERJ7|E7ERJ7_HUMAN,tr|A0A7I2V598|A0A7I2V598_HUMAN,tr|A0A7I2YQ88|A0A7I2YQ88_HUMAN,tr|H0Y5F5|H0Y5F5_HUMAN,tr|H0YBN4|H0YBN4_HUMAN,tr|A0A087WTT1|A0A087WTT1_HUMAN,tr|A0A7I2YQ90|A0A7I2YQ90_HUMAN,tr|A0A7I2V4N4|A0A7I2V4N4_HUMAN,tr|E7EQV3|E7EQV3_HUMAN" 18 1227.6834 1.37 46032 11672 3 1227.683631 410.2351 Polyadenylate-binding protein 4 OS=Homo sapiens OX=9606 GN=PABPC4 PE=1 SV=1 8.54 2348.8 - 1.70E+06 - - - 0.1686 - 1.998 0.331 - 88.4 1 2 1 0.0002 10 0 0 0 3.56E+08 2.60E+08 - - - 4.2516 1 221125_WJC_METTL3_EV_vs_WT_F04.11674.11674.3 2.59E-07 14/40 K.RPGYGAYDAFK.H "sp|P05198|IF2A_HUMAN,tr|H0YJS4|H0YJS4_HUMAN,tr|G3V4T5|G3V4T5_HUMAN" 3 1243.5986 0.94 46034 11674 3 1243.598624 415.5401 Eukaryotic translation initiation factor 2 subunit 1 OS=Homo sapiens OX=9606 GN=EIF2S1 PE=1 SV=3 8.5 2349 - 1.60E+06 - - - 0.0418 - 2.633 0.535 - 263.2 1 2 0 0.0001 11 0 0 0 3.95E+07 4.18E+07 - - - 7.255 0.9987 221125_WJC_METTL3_EV_vs_WT_F04.11675.11675.3 0.114 Nov-36 K.AKEFTNVYIK.N "sp|Q13310|PABP4_HUMAN,sp|P11940|PABP1_HUMAN,tr|A0A7I2V5W9|A0A7I2V5W9_HUMAN,tr|A0A7I2YQE4|A0A7I2YQE4_HUMAN,tr|A0A7I2V649|A0A7I2V649_HUMAN,tr|B1ANR0|B1ANR0_HUMAN,tr|A0A7I2V4L7|A0A7I2V4L7_HUMAN,tr|H0YCC8|H0YCC8_HUMAN,tr|H0YAR2|H0YAR2_HUMAN,tr|E7ERJ7|E7ERJ7_HUMAN,tr|A0A7I2V598|A0A7I2V598_HUMAN,tr|A0A7I2YQ88|A0A7I2YQ88_HUMAN,tr|H0Y5F5|H0Y5F5_HUMAN,tr|H0YBN4|H0YBN4_HUMAN,tr|A0A087WTT1|A0A087WTT1_HUMAN,tr|A0A7I2YQ90|A0A7I2YQ90_HUMAN,tr|A0A7I2V4N4|A0A7I2V4N4_HUMAN,tr|E7EQV3|E7EQV3_HUMAN" 18 1211.655 1.37 46035 11675 3 1211.654891 404.8923 Polyadenylate-binding protein 4 OS=Homo sapiens OX=9606 GN=PABPC4 PE=1 SV=1 8.54 2349.1 - 1.36E+06 - - - -0.1098 - 2.192 0.307 - 211.7 1 2 1 -0.0001 10 0 0 0 3.55E+08 2.59E+08 - - - 4.2547 0.9938 221125_WJC_METTL3_EV_vs_WT_F04.11676.11676.2 2.65E-06 13/22 S.K[136.11]LSAMMGAVAEK[136.11].K "sp|Q86U44|MTA70_HUMAN,tr|F5H6D8|F5H6D8_HUMAN,tr|H0YFV6|H0YFV6_HUMAN,tr|B4DTN4|B4DTN4_HUMAN" 4 1250.6698 0 46036 11676 2 1250.670865 626.3422 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 8.59 2349.1 - 1.18E+06 - - - 0.8795 - 2.731 0.539 - 411.2 1 1 0 0.0011 12 0 0 0 3.27E+05 6.82E+07 - - - 5.6652 0.9971 221125_WJC_METTL3_EV_vs_WT_F04.11677.11677.3 0.00127 Dec-48 K.LGDLK[136.11]EEGDVMDK[136.11].T "sp|Q14671|PUM1_HUMAN,tr|Q5T1Z8|Q5T1Z8_HUMAN,tr|H0YEH2|H0YEH2_HUMAN,tr|Q5T1Z4|Q5T1Z4_HUMAN" 4 1463.7149 10.99 46037 11677 3 1463.712159 488.9122 Pumilio homolog 1 OS=Homo sapiens OX=9606 GN=PUM1 PE=1 SV=3 4.11 2349.2 - 1.24E+06 - - - -1.8453 - 2.159 0.303 - 144.4 1 2 1 -0.0027 13 0 0 0 7.99E+07 7.27E+06 - - - 4.0041 0.9997 221125_WJC_METTL3_EV_vs_WT_F04.11680.11680.2 2.43E-05 13/26 R.TPQAPASANLVGPR[166.11].S sp|Q9UQ35|SRRM2_HUMAN 1 1387.7447 1.04 46040 11680 2 1387.747607 694.8796 Serine\arginine repetitive matrix protein 2 OS=Homo sapiens OX=9606 GN=SRRM2 PE=1 SV=2 9.41 2349.5 - 452671 - - - 2.0717 - 2.418 0.499 - 410.8 1 2 0 0.0029 14 0 0 0 1.18E+07 1.13E+07 - - - 4.9414 0.9993 221125_WJC_METTL3_EV_vs_WT_F04.11683.11683.2 0.708 16-Aug K.SNVNIGNLR[166.11].K "sp|Q9Y2H2|SAC2_HUMAN,tr|A0A3B3IRJ9|A0A3B3IRJ9_HUMAN,tr|A0A3B3ITL0|A0A3B3ITL0_HUMAN" 3 995.5388 0.92 46043 11683 2 995.53824 498.7767 Phosphatidylinositide phosphatase SAC2 OS=Homo sapiens OX=9606 GN=INPP5F PE=1 SV=3 9.47 2349.9 - 375833 - - - -0.5243 - 1.74 0.274 - 273.8 1 2 0 -0.0005 9 0 0 0 5.40E+06 5.88E+06 - - - 2.667 0.8345 221125_WJC_METTL3_EV_vs_WT_F04.11684.11684.2 9.39 20-May K.ITTQLDQVTAK[136.11].L sp|Q15075|EEA1_HUMAN 1 1224.6805 0.83 46044 11684 2 1224.680218 613.3475 Early endosome antigen 1 OS=Homo sapiens OX=9606 GN=EEA1 PE=1 SV=2 5.84 2350 - 331975 - - - -0.2441 - 0.891 0.065 - 49.5 11 2 0 -0.0003 11 0 0 0 2.68E+06 3.22E+06 - - - -1.2564 0.9991 221125_WJC_METTL3_EV_vs_WT_F04.11685.11685.2 0.00371 22-Dec K.ELTAPDENIPAK[136.11].L "sp|P11387|TOP1_HUMAN,tr|A0A7P0T852|A0A7P0T852_HUMAN" 2 1304.6703 1.07 46045 11685 2 1304.671358 653.3424 DNA topoisomerase 1 OS=Homo sapiens OX=9606 GN=TOP1 PE=1 SV=2 4.14 2350.2 - 1.41E+06 - - - 0.7757 - 1.874 0.26 - 488.2 1 2 0 0.001 12 0 0 0 1.95E+07 1.82E+07 - - - 2.6136 0.9998 221125_WJC_METTL3_EV_vs_WT_F04.11688.11688.2 0.00137 16-Oct K.TGEEINFGK[136.11].L "sp|P49959|MRE11_HUMAN,tr|F8W7U8|F8W7U8_HUMAN" 2 1001.4909 1.76 46048 11688 2 1001.490318 501.7527 Double-strand break repair protein MRE11 OS=Homo sapiens OX=9606 GN=MRE11 PE=1 SV=3 4.53 2350.6 - 287997 - - - -0.6061 - 2.173 0.383 - 524.6 1 2 0 -0.0006 9 0 0 0 2.94E+07 1.67E+07 - - - 4.115 0.9996 221125_WJC_METTL3_EV_vs_WT_F04.11689.11689.3 0.0219 Nov-40 K.GHLDALTADVK[136.11].E sp|P57740|NU107_HUMAN 1 1146.6124 1.25 46049 11689 3 1146.613903 383.2114 Nuclear pore complex protein Nup107 OS=Homo sapiens OX=9606 GN=NUP107 PE=1 SV=1 5.21 2350.7 - 285803 - - - 1.2777 - 2.01 0.327 - 149.2 1 2 0 0.0015 11 0 0 0 3.40E+06 2.72E+06 - - - 4.1686 0.9999 221125_WJC_METTL3_EV_vs_WT_F04.11691.11691.2 7.77E-05 16-Sep K.NQEIEELTK[136.11].L "sp|O75410|TACC1_HUMAN,tr|E7EVI4|E7EVI4_HUMAN,tr|B4E3H6|B4E3H6_HUMAN,tr|H0YAY0|H0YAY0_HUMAN,tr|H0YBT8|H0YBT8_HUMAN,tr|E7ET87|E7ET87_HUMAN" 6 1110.5648 1.19 46050 11691 2 1110.564634 556.2897 Transforming acidic coiled-coil-containing protein 1 OS=Homo sapiens OX=9606 GN=TACC1 PE=1 SV=2 4.25 2350.9 - 1.64E+06 - - - -0.1666 - 2.159 0.442 - 468.9 1 2 0 -0.0002 9 0 0 0 9.48E+07 7.99E+07 - - - 4.5322 1 221125_WJC_METTL3_EV_vs_WT_F04.11692.11692.3 5.45E-05 15/44 K.LLTHNLLSSHVR[166.11].G sp|Q9UI30|TR112_HUMAN 1 1398.7971 1.97 46051 11692 3 1398.798877 467.273 Multifunctional methyltransferase subunit TRM112-like protein OS=Homo sapiens OX=9606 GN=TRMT112 PE=1 SV=1 9.76 2351 - 875258 - - - 1.2689 - 2.944 0.494 - 376.7 1 2 0 0.0018 12 0 0 0 1.30E+08 6.60E+07 - - - 7.0401 0.9997 221125_WJC_METTL3_EV_vs_WT_F04.11695.11695.2 0.00152 16-Sep K.NQEIEELTK.L "sp|O75410|TACC1_HUMAN,tr|E7EVI4|E7EVI4_HUMAN,tr|B4E3H6|B4E3H6_HUMAN,tr|H0YAY0|H0YAY0_HUMAN,tr|H0YBT8|H0YBT8_HUMAN,tr|E7ET87|E7ET87_HUMAN" 6 1102.5506 1.19 46054 11695 2 1102.550237 552.2826 Transforming acidic coiled-coil-containing protein 1 OS=Homo sapiens OX=9606 GN=TACC1 PE=1 SV=2 4.25 2351.2 - 1.90E+06 - - - -0.3465 - 2.225 0.33 - 472.4 1 2 0 -0.0004 9 0 0 0 9.48E+07 7.99E+07 - - - 3.792 0.9997 221125_WJC_METTL3_EV_vs_WT_F04.11696.11696.3 0.000367 Dec-40 K.VAEK[136.11]LEALSVK[136.11].E "sp|P43487|RANG_HUMAN,tr|C9JXG8|C9JXG8_HUMAN,tr|F6WQW2|F6WQW2_HUMAN" 3 1201.7253 0.67 46055 11696 3 1201.724734 401.5824 Ran-specific GTPase-activating protein OS=Homo sapiens OX=9606 GN=RANBP1 PE=1 SV=1 6.11 2351.4 - 1.14E+06 - - - -0.4618 - 2.46 0.407 - 193 1 2 1 -0.0006 11 0 0 0 1.00E+07 1.50E+07 - - - 5.6347 0.9974 221125_WJC_METTL3_EV_vs_WT_F04.11697.11697.2 0.167 18-Dec K.AKEFTNVYIK.N "sp|Q13310|PABP4_HUMAN,sp|P11940|PABP1_HUMAN,tr|A0A7I2V5W9|A0A7I2V5W9_HUMAN,tr|A0A7I2YQE4|A0A7I2YQE4_HUMAN,tr|A0A7I2V649|A0A7I2V649_HUMAN,tr|B1ANR0|B1ANR0_HUMAN,tr|A0A7I2V4L7|A0A7I2V4L7_HUMAN,tr|H0YCC8|H0YCC8_HUMAN,tr|H0YAR2|H0YAR2_HUMAN,tr|E7ERJ7|E7ERJ7_HUMAN,tr|A0A7I2V598|A0A7I2V598_HUMAN,tr|A0A7I2YQ88|A0A7I2YQ88_HUMAN,tr|H0Y5F5|H0Y5F5_HUMAN,tr|H0YBN4|H0YBN4_HUMAN,tr|A0A087WTT1|A0A087WTT1_HUMAN,tr|A0A7I2YQ90|A0A7I2YQ90_HUMAN,tr|A0A7I2V4N4|A0A7I2V4N4_HUMAN,tr|E7EQV3|E7EQV3_HUMAN" 18 1211.655 1.28 46056 11697 2 1211.655897 606.8348 Polyadenylate-binding protein 4 OS=Homo sapiens OX=9606 GN=PABPC4 PE=1 SV=1 8.54 2351.5 - 996142 - - - 0.7205 - 2.12 0.398 - 269.8 1 2 1 0.0009 10 0 0 0 5.97E+07 4.67E+07 - - - 4.0778 0.9983 221125_WJC_METTL3_EV_vs_WT_F04.11698.11698.2 0.000325 20-Sep K.YTISQEAYDQR[166.11].Q "sp|Q99426|TBCB_HUMAN,tr|A0A494C0X0|A0A494C0X0_HUMAN,tr|K7EP07|K7EP07_HUMAN,tr|K7EK42|K7EK42_HUMAN" 4 1382.6342 0.39 46057 11698 2 1382.639861 692.3244 Tubulin-folding cofactor B OS=Homo sapiens OX=9606 GN=TBCB PE=1 SV=2 4.37 2351.6 - 965674 - - - 4.1095 - 1.948 0.474 - 175.7 1 2 0 0.0057 11 0 0 0 5.05E+06 1.30E+07 - - - 4.344 0.9998 221125_WJC_METTL3_EV_vs_WT_F04.11700.11700.2 0.000308 20-Oct K.NLEDDTLSEC[160.03]K[136.11].Q "sp|Q14966|ZN638_HUMAN,tr|A0A096LPI0|A0A096LPI0_HUMAN" 2 1330.5802 1.34 46059 11700 2 1330.579744 666.2974 Zinc finger protein 638 OS=Homo sapiens OX=9606 GN=ZNF638 PE=1 SV=2 3.92 2351.8 - 718776 - - - -0.351 - 2.046 0.474 - 254.9 1 2 0 -0.0005 11 0 0 0 1.01E+07 7.50E+06 - - - 4.4785 0.9999 221125_WJC_METTL3_EV_vs_WT_F04.11701.11701.2 6.71E-08 20-Nov K.NLEDDTLSEC[160.03]K.Q "sp|Q14966|ZN638_HUMAN,tr|A0A096LPI0|A0A096LPI0_HUMAN" 2 1322.566 0.93 46060 11701 2 1322.565816 662.2903 Zinc finger protein 638 OS=Homo sapiens OX=9606 GN=ZNF638 PE=1 SV=2 3.92 2351.9 - 690396 - - - -0.1474 - 2.168 0.493 - 369.2 1 2 0 -0.0002 11 0 0 0 5.92E+06 6.34E+06 - - - 4.7756 0.9992 221125_WJC_METTL3_EV_vs_WT_F04.11703.11703.3 0.00033 Oct-44 R.LYKDDQLLDDGK.T "sp|Q15370|ELOB_HUMAN,tr|B8ZZU8|B8ZZU8_HUMAN" 2 1421.7038 1.19 46062 11703 3 1421.703711 474.9086 Elongin-B OS=Homo sapiens OX=9606 GN=ELOB PE=1 SV=1 4.14 2352.2 - 615219 - - - -0.0802 - 1.924 0.392 - 134 1 2 1 -0.0001 12 0 0 0 7.92E+06 6.65E+06 - - - 4.7243 0.9999 221125_WJC_METTL3_EV_vs_WT_F04.11704.11704.2 0.000694 24-Dec K.LNEIVGNEDTVSR.L "sp|P35250|RFC2_HUMAN,tr|F8WC37|F8WC37_HUMAN,tr|H7C5G4|H7C5G4_HUMAN,tr|H7C5A0|H7C5A0_HUMAN,tr|H7C5Q7|H7C5Q7_HUMAN,tr|H7C5S7|H7C5S7_HUMAN,tr|H7C5P1|H7C5P1_HUMAN" 7 1444.7158 0.63 46063 11704 2 1444.71532 723.3652 Replication factor C subunit 2 OS=Homo sapiens OX=9606 GN=RFC2 PE=1 SV=3 4.14 2352.3 - 423701 - - - -0.3232 - 2.549 0.463 - 444.2 1 2 0 -0.0005 13 0 0 0 1.61E+07 2.55E+07 - - - 4.8621 0.9883 221125_WJC_METTL3_EV_vs_WT_F04.11705.11705.2 0.0098 14/24 K.TLGEC[160.03]GFTSQTAR[166.11].P "sp|Q15370|ELOB_HUMAN,tr|I3L0M9|I3L0M9_HUMAN,tr|B8ZZU8|B8ZZU8_HUMAN" 3 1436.6593 0.97 46064 11705 2 1436.656392 719.337 Elongin-B OS=Homo sapiens OX=9606 GN=ELOB PE=1 SV=1 5.66 2352.4 - 291517 - - - -2.0576 - 2.714 0.53 - 526 1 1 0 -0.003 13 0 0 0 6.82E+06 7.06E+06 - - - 5.5171 0.9999 221125_WJC_METTL3_EV_vs_WT_F04.11713.11713.2 2.20E-06 22-Oct R.AQPSASLGVGYR.T sp|Q96PK6|RBM14_HUMAN 1 1204.62 1.75 46070 11713 2 1204.619783 603.3173 RNA-binding protein 14 OS=Homo sapiens OX=9606 GN=RBM14 PE=1 SV=2 8.79 2353.2 - 2.82E+06 - - - -0.21 - 2.046 0.582 - 337.9 1 2 0 -0.0003 12 0 0 0 9.72E+08 5.56E+08 - - - 5.2232 0.9993 221125_WJC_METTL3_EV_vs_WT_F04.11714.11714.2 0.0618 12-Jul K.YGLNMC[160.03]R.Q "sp|P62273|RS29_HUMAN,tr|A0A2R8Y6P7|A0A2R8Y6P7_HUMAN,tr|A0A2R8Y851|A0A2R8Y851_HUMAN,tr|A0A087WTT6|A0A087WTT6_HUMAN" 4 912.3946 1.1 46071 11714 2 912.393498 457.2046 40S ribosomal protein S29 OS=Homo sapiens OX=9606 GN=RPS29 PE=1 SV=2 8.22 2353.4 - 1.47E+06 - - - -1.2001 - 1.54 0.342 - 178.4 1 2 0 -0.0011 7 0 0 0 1.62E+07 1.48E+07 - - - 2.9348 0.9997 221125_WJC_METTL3_EV_vs_WT_F04.11728.11728.2 0.00339 18-Oct K.DLIEDSSVQK[136.11].D "sp|Q71RC2|LARP4_HUMAN,tr|X6RLN4|X6RLN4_HUMAN" 2 1140.5754 0.001 46083 11728 2 1140.574154 571.295 La-related protein 4 OS=Homo sapiens OX=9606 GN=LARP4 PE=1 SV=3 4.03 2354.7 - 1.02E+06 - - - -1.0775 - 1.993 0.378 - 298.9 1 2 0 -0.0012 10 0 0 0 0.00E+00 3.55E+07 - - - 3.7575 0.9966 221125_WJC_METTL3_EV_vs_WT_F04.11729.11729.3 0.0711 Sep-36 R.DFVTTRPALK.E sp|Q9UN81|LORF1_HUMAN 1 1146.6397 1.26 46084 11729 3 1146.639028 383.2205 LINE-1 retrotransposable element ORF1 protein OS=Homo sapiens OX=9606 GN=L1RE1 PE=1 SV=1 8.75 2354.9 - 791340 - - - -0.593 - 1.453 0.255 - 99.3 1 2 0 -0.0007 10 0 0 0 7.82E+06 6.19E+06 - - - 2.474 0.8593 221125_WJC_METTL3_EV_vs_WT_F04.11734.11734.2 0.0334 16-Aug N.NIEQISSYK.S "sp|P13645|K1C10_HUMAN,tr|A0A1B0GVI3|A0A1B0GVI3_HUMAN" 2 1080.5451 5.81 46088 11734 2 1080.548686 541.2798 "Keratin, type I cytoskeletal 10 OS=Homo sapiens OX=9606 GN=KRT10 PE=1 SV=6" 6 2355.6 - 700584 - - - 3.2826 - 1.826 0.308 - 176.8 1 1 0 0.0035 9 0 0 0 8.69E+06 1.50E+06 - - - 3.0568 0.9997 221125_WJC_METTL3_EV_vs_WT_F04.11736.11736.2 2.00E-06 16-Sep R.C[160.03]GGSELNFR.R "sp|Q8IWA0|WDR75_HUMAN,tr|F8WC81|F8WC81_HUMAN,tr|F8WE20|F8WE20_HUMAN" 3 1038.4553 1 46089 11736 2 1038.456579 520.2349 WD repeat-containing protein 75 OS=Homo sapiens OX=9606 GN=WDR75 PE=1 SV=1 5.99 2355.8 - 730768 - - - 1.2519 - 2.087 0.378 - 484.9 1 2 0 0.0013 9 0 0 0 1.18E+07 1.18E+07 - - - 3.961 0.999 221125_WJC_METTL3_EV_vs_WT_F04.11740.11740.2 0.000325 20-Nov K.FIC[160.03]TTSAIQNR[166.11].F "sp|P53396|ACLY_HUMAN,tr|K7ESG8|K7ESG8_HUMAN" 2 1319.6531 0.95 46093 11740 2 1319.658405 660.8338 ATP-citrate synthase OS=Homo sapiens OX=9606 GN=ACLY PE=1 SV=3 8.25 2356.2 - 434481 - - - 3.9897 - 2.298 0.531 - 356.6 1 2 0 0.0053 11 0 0 0 1.23E+07 1.29E+07 - - - 5.2122 0.9979 221125_WJC_METTL3_EV_vs_WT_F04.11742.11742.3 0.189 Oct-40 K.AGVSVK[136.11]PFQVK[136.11].N "sp|Q02880|TOP2B_HUMAN,tr|E9PCY5|E9PCY5_HUMAN" 2 1174.7045 1.24 46095 11742 3 1174.704952 392.5754 DNA topoisomerase 2-beta OS=Homo sapiens OX=9606 GN=TOP2B PE=1 SV=3 10 2356.4 - 275259 - - - 0.3899 - 1.738 0.24 - 79.1 1 2 0 0.0005 11 0 0 0 6.08E+06 4.90E+06 - - - 2.7859 0.9987 221125_WJC_METTL3_EV_vs_WT_F04.11745.11745.3 0.021 Oct-44 R.LSEHSGPPIVIR[166.11].D "sp|Q6ZRI6|CO039_HUMAN,tr|H3BMJ2|H3BMJ2_HUMAN" 2 1313.7331 3.09 46096 11745 3 1313.733013 438.9183 Uncharacterized protein C15orf39 OS=Homo sapiens OX=9606 GN=C15orf39 PE=1 SV=3 6.75 2356.8 - 327474 - - - -0.07 - 1.966 0.244 - 117.4 1 2 0 -0.0001 12 0 0 0 1.62E+07 5.25E+06 - - - 3.1341 1 221125_WJC_METTL3_EV_vs_WT_F04.11747.11747.3 2.47E-06 16/40 K.VAC[160.03]IGAWHPAR.V "sp|Q92901|RL3L_HUMAN,sp|P39023|RL3_HUMAN,tr|G5E9G0|G5E9G0_HUMAN,tr|B5MCW2|B5MCW2_HUMAN,tr|H7C422|H7C422_HUMAN" 5 1236.6186 0.86 46097 11747 3 1236.616827 413.2135 60S ribosomal protein L3-like OS=Homo sapiens OX=9606 GN=RPL3L PE=2 SV=3 8.23 2357.1 - 862165 - - - -1.4305 - 2.85 0.444 - 543.7 1 2 0 -0.0018 11 0 0 0 2.33E+07 2.70E+07 - - - 6.4649 0.9353 221125_WJC_METTL3_EV_vs_WT_F04.11748.11748.2 9.14 22-Jun K.AEGVIDGYADEK.T "sp|Q99996|AKAP9_HUMAN,tr|A0A0A0MRF6|A0A0A0MRF6_HUMAN,tr|A0A7P0TBH8|A0A7P0TBH8_HUMAN,tr|A0A7P0TAX3|A0A7P0TAX3_HUMAN,tr|A0A7P0T9A9|A0A7P0T9A9_HUMAN,tr|A0A7P0T8N5|A0A7P0T8N5_HUMAN,tr|A0A2R8Y590|A0A2R8Y590_HUMAN,tr|A0A7P0TBI4|A0A7P0TBI4_HUMAN,tr|A0A7P0Z4Q5|A0A7P0Z4Q5_HUMAN,tr|A0A7P0Z4N5|A0A7P0Z4N5_HUMAN,tr|A0A7P0TAD6|A0A7P0TAD6_HUMAN,tr|A0A7P0T939|A0A7P0T939_HUMAN,tr|A0A7P0T928|A0A7P0T928_HUMAN,tr|A0A7P0TAA2|A0A7P0TAA2_HUMAN" 14 1265.5776 0.25 46098 11748 2 1265.574589 633.7961 A-kinase anchor protein 9 OS=Homo sapiens OX=9606 GN=AKAP9 PE=1 SV=4 3.92 2357.2 - 228291 - - - -2.3491 - 1.098 0.119 - 103.4 2 2 0 -0.003 12 0 0 0 1.43E+06 5.70E+06 - - - 0.0305 0.9998 221125_WJC_METTL3_EV_vs_WT_F04.11749.11749.2 0.00186 18-Nov K.QSPQTSFPYK.L "sp|Q8IWC1|MA7D3_HUMAN,tr|A0A0A0MRP0|A0A0A0MRP0_HUMAN" 2 1181.5717 1.65 46099 11749 2 1181.573791 591.7931 MAP7 domain-containing protein 3 OS=Homo sapiens OX=9606 GN=MAP7D3 PE=1 SV=2 8.59 2357.3 - 863326 - - - 1.7798 - 2.412 0.454 - 611.4 1 2 0 0.0021 10 0 0 0 2.49E+07 1.51E+07 - - - 4.8512 0.9999 221125_WJC_METTL3_EV_vs_WT_F04.11755.11755.3 0.00021 14/48 K.VGSLYPEMSAHER.S "sp|Q14203|DCTN1_HUMAN,tr|A0A804CDA6|A0A804CDA6_HUMAN,tr|E7EX90|E7EX90_HUMAN,tr|A0A7P0Z4C3|A0A7P0Z4C3_HUMAN,tr|Q6AWB1|Q6AWB1_HUMAN" 5 1474.6875 1.85 46103 11755 3 1474.686351 492.5698 Dynactin subunit 1 OS=Homo sapiens OX=9606 GN=DCTN1 PE=1 SV=3 5.4 2358.1 - 1.01E+06 - - - -0.7541 - 2.187 0.443 - 229.8 1 2 0 -0.0011 13 0 0 0 8.68E+07 4.68E+07 - - - 5.6004 1 221125_WJC_METTL3_EV_vs_WT_F04.11756.11756.3 0.00121 Oct-32 K.YFDEHYEYR.H sp|P33552|CKS2_HUMAN 1 1320.5411 2.18 46104 11756 3 1320.539968 441.1876 Cyclin-dependent kinases regulatory subunit 2 OS=Homo sapiens OX=9606 GN=CKS2 PE=1 SV=1 4.65 2358.2 - 533306 - - - -0.8701 - 1.791 0.512 - 119.7 1 2 0 -0.0011 9 0 0 0 6.67E+06 3.06E+06 - - - 6.0043 0.9999 221125_WJC_METTL3_EV_vs_WT_F04.11757.11757.3 0.000488 Nov-48 K.VGSLYPEMSAHER[166.11].S "sp|Q14203|DCTN1_HUMAN,tr|A0A804CDA6|A0A804CDA6_HUMAN,tr|E7EX90|E7EX90_HUMAN,tr|A0A7P0Z4C3|A0A7P0Z4C3_HUMAN,tr|Q6AWB1|Q6AWB1_HUMAN" 5 1484.6957 1.66 46105 11757 3 1484.693557 495.9059 Dynactin subunit 1 OS=Homo sapiens OX=9606 GN=DCTN1 PE=1 SV=3 5.4 2358.3 - 402812 - - - -1.4656 - 2.468 0.42 - 165.6 1 2 0 -0.0022 13 0 0 0 3.87E+07 2.33E+07 - - - 5.6714 0.9937 221125_WJC_METTL3_EV_vs_WT_F04.11759.11759.2 0.0003 24-Sep M.APSVPAAEPEYPK.G "sp|P54819|KAD2_HUMAN,tr|A0A5F9ZHP2|A0A5F9ZHP2_HUMAN,tr|G3V213|G3V213_HUMAN,tr|F8VY04|F8VY04_HUMAN,tr|F8W1A4|F8W1A4_HUMAN,tr|A0A5K1VW67|A0A5K1VW67_HUMAN,tr|F8VPP1|F8VPP1_HUMAN,tr|F8VZG5|F8VZG5_HUMAN" 8 1354.6769 2.21 46107 11759 2 1354.683516 678.3457 "Adenylate kinase 2, mitochondrial OS=Homo sapiens OX=9606 GN=AK2 PE=1 SV=2" 4.53 2358.6 - 255424 - - - 4.8971 - 1.805 0.389 - 219.7 1 2 0 0.0066 13 0 0 0 1.84E+07 8.32E+06 - - - 3.4278 0.9956 221125_WJC_METTL3_EV_vs_WT_F04.11760.11760.2 0.596 22-Aug R.LQAQSLSTVGPR[166.11].L sp|O43290|SNUT1_HUMAN 1 1265.6967 1.92 46108 11760 2 1265.696791 633.8556 U4\U6.U5 tri-snRNP-associated protein 1 OS=Homo sapiens OX=9606 GN=SART1 PE=1 SV=1 9.75 2358.7 - 175783 - - - 0.0561 - 1.566 0.151 - 202.5 2 2 0 0.0001 12 0 0 0 2.89E+07 1.50E+07 - - - 1.2019 1 221125_WJC_METTL3_EV_vs_WT_F04.11765.11765.2 0.000164 13/22 R.IDVDTEDVGDER[166.11].V "sp|Q9Y2W6|TDRKH_HUMAN,tr|F6TB26|F6TB26_HUMAN,tr|B7ZAG4|B7ZAG4_HUMAN,tr|E9PKN8|E9PKN8_HUMAN,tr|Q5SZR4|Q5SZR4_HUMAN" 5 1371.6029 1.64 46112 11765 2 1371.602626 686.8087 Tudor and KH domain-containing protein OS=Homo sapiens OX=9606 GN=TDRKH PE=1 SV=2 3.66 2359.2 - 947760 - - - -0.2275 - 2.612 0.583 - 758.1 1 2 0 -0.0003 12 0 0 0 2.30E+07 1.40E+07 - - - 5.8732 0.999 221125_WJC_METTL3_EV_vs_WT_F04.11766.11766.2 0.0264 20-Sep R.LSVASTPISQR[166.11].R "sp|Q9BXS6|NUSAP_HUMAN,tr|H0YMD2|H0YMD2_HUMAN" 2 1167.6487 2.47 46113 11766 2 1167.648271 584.8316 Nucleolar and spindle-associated protein 1 OS=Homo sapiens OX=9606 GN=NUSAP1 PE=1 SV=1 9.75 2359.3 - 838488 - - - -0.3734 - 1.909 0.219 - 199.2 1 2 0 -0.0004 11 0 0 0 1.68E+07 6.82E+06 - - - 2.4075 0.9998 221125_WJC_METTL3_EV_vs_WT_F04.11767.11767.2 9.85E-05 18-Oct K.SAVGFEYQGK[136.11].T "sp|Q14247|SRC8_HUMAN,sp|Q14247|SRC8_HUMAN" 2 1092.5331 0.4 46114 11767 2 1092.533252 547.2738 Src substrate cortactin OS=Homo sapiens OX=9606 GN=CTTN PE=1 SV=2 5.72 2359.5 - 514135 - - - 0.1162 - 2.117 0.452 - 438.9 1 2 0 0.0001 10 0 0 0 6.19E+06 1.55E+07 - - - 4.4729 0.9996 221125_WJC_METTL3_EV_vs_WT_F04.11768.11768.3 0.00215 14/36 R.VPAPFK[136.11]PITR[166.11].K "sp|Q9NX20|RM16_HUMAN,tr|E9PI14|E9PI14_HUMAN" 2 1142.6931 0.001 46115 11768 3 1142.689815 381.905 "39S ribosomal protein L16, mitochondrial OS=Homo sapiens OX=9606 GN=MRPL16 PE=1 SV=1" 11 2359.6 - 408291 - - - -2.8617 - 2.231 0.372 - 412.5 1 2 0 -0.0033 10 0 0 0 0.00E+00 9.93E+07 - - - 5.03 1 221125_WJC_METTL3_EV_vs_WT_F04.11771.11771.3 4.16E-05 16/44 K.LLTHNLLSSHVR.G sp|Q9UI30|TR112_HUMAN 1 1388.7888 1.13 46117 11771 3 1388.788235 463.9369 Multifunctional methyltransferase subunit TRM112-like protein OS=Homo sapiens OX=9606 GN=TRMT112 PE=1 SV=1 9.76 2359.9 - 3.61E+06 - - - -0.4299 - 2.809 0.454 - 469.7 1 2 0 -0.0006 12 0 0 0 7.17E+07 6.33E+07 - - - 6.4643 1 221125_WJC_METTL3_EV_vs_WT_F04.11773.11773.3 4.24E-08 18/56 R.LLAEGHPDPDAELQR[166.11].M sp|P49756|RBM25_HUMAN 1 1669.8299 0.88 46118 11773 3 1669.828372 557.6172 RNA-binding protein 25 OS=Homo sapiens OX=9606 GN=RBM25 PE=1 SV=3 4.31 2360.1 - 2.67E+06 - - - -0.9264 - 2.667 0.641 - 358.6 1 2 0 -0.0015 15 0 0 0 3.72E+07 4.22E+07 - - - 8.2458 0.9802 221125_WJC_METTL3_EV_vs_WT_F04.11774.11774.2 1.84 12-Jul R.SESWNLK.D sp|P19474|RO52_HUMAN 1 862.4185 1.69 46119 11774 2 862.417679 432.2165 E3 ubiquitin-protein ligase TRIM21 OS=Homo sapiens OX=9606 GN=TRIM21 PE=1 SV=1 5.72 2360.3 - 1.28E+06 - - - -0.9311 - 1.24 0.073 - 228.3 1 2 0 -0.0008 7 0 0 0 2.92E+07 1.73E+07 - - - 0.2615 0.9997 221125_WJC_METTL3_EV_vs_WT_F04.11778.11778.2 0.000678 22-Dec K.ELTAPDENIPAK.L "sp|P11387|TOP1_HUMAN,tr|A0A7P0T852|A0A7P0T852_HUMAN" 2 1296.6561 1.19 46123 11778 2 1296.658447 649.3353 DNA topoisomerase 1 OS=Homo sapiens OX=9606 GN=TOP1 PE=1 SV=2 4.14 2360.8 - 832578 - - - 1.7746 - 2.055 0.493 - 477.2 1 2 0 0.0023 12 0 0 0 2.21E+07 1.85E+07 - - - 4.5767 1 221125_WJC_METTL3_EV_vs_WT_F04.11779.11779.3 0.000155 Nov-36 K.LEHEYIQNFK.L sp|Q15691|MARE1_HUMAN 1 1319.651 0.99 46124 11779 3 1319.651142 440.8909 Microtubule-associated protein RP\EB family member 1 OS=Homo sapiens OX=9606 GN=MAPRE1 PE=1 SV=3 5.4 2360.9 - 772730 - - - 0.1068 - 2.211 0.473 - 223.2 1 2 0 0.0001 10 0 0 0 1.12E+07 1.14E+07 - - - 6.1306 0.9998 221125_WJC_METTL3_EV_vs_WT_F04.11781.11781.3 0.000281 14/48 R.VLEVEK[136.11]EDTEELR[166.11].Q "sp|Q9UKJ3|GPTC8_HUMAN,tr|K7EKU0|K7EKU0_HUMAN" 2 1605.8217 0.92 46126 11781 3 1605.822083 536.2812 G patch domain-containing protein 8 OS=Homo sapiens OX=9606 GN=GPATCH8 PE=1 SV=2 4.14 2361.2 - 483242 - - - 0.2684 - 2.542 0.451 - 321.7 1 2 1 0.0004 13 0 0 0 1.69E+07 1.84E+07 - - - 6.0976 0.9995 221125_WJC_METTL3_EV_vs_WT_F04.11782.11782.2 0.0207 24-Oct R.AWQGAMDAGAASR.E sp|Q14151|SAFB2_HUMAN 1 1290.5775 1.66 46127 11782 2 1290.579169 646.296 Scaffold attachment factor B2 OS=Homo sapiens OX=9606 GN=SAFB2 PE=1 SV=1 5.88 2361.3 - 660649 - - - 1.2785 - 1.871 0.376 - 203.4 1 2 0 0.0016 13 0 0 0 9.53E+06 5.76E+06 - - - 3.4255 0.9915 221125_WJC_METTL3_EV_vs_WT_F04.11783.11783.2 0.000442 18-Oct L.TVQHPLEESR.D "sp|Q6P3W7|SCYL2_HUMAN,tr|F8VSC5|F8VSC5_HUMAN,tr|A0A0U1RQQ9|A0A0U1RQQ9_HUMAN" 3 1194.5993 0.16 46128 11783 2 1194.598625 598.3069 SCY1-like protein 2 OS=Homo sapiens OX=9606 GN=SCYL2 PE=1 SV=1 5.37 2361.4 - 453640 - - - -0.565 - 2.265 0.45 - 340.1 1 1 0 -0.0007 10 0 0 0 4.73E+06 2.92E+07 - - - 4.6466 1 221125_WJC_METTL3_EV_vs_WT_F04.11784.11784.2 8.62E-07 15/30 K.AFGPGLQGGSAGSPAR[166.11].F "sp|P21333|FLNA_HUMAN,tr|Q60FE5|Q60FE5_HUMAN" 2 1438.7192 1.15 46129 11784 2 1438.722422 720.3669 Filamin-A OS=Homo sapiens OX=9606 GN=FLNA PE=1 SV=4 9.79 2361.5 - 349156 - - - 2.2075 - 2.815 0.595 - 432 1 2 0 0.0032 16 0 0 0 2.99E+07 2.60E+07 - - - 5.9792 0.9987 221125_WJC_METTL3_EV_vs_WT_F04.11785.11785.2 0.00547 18-Dec K.SAVGFEYQGK.T "sp|Q14247|SRC8_HUMAN,sp|Q14247|SRC8_HUMAN" 2 1084.5189 0.42 46130 11785 2 1084.516199 543.2667 Src substrate cortactin OS=Homo sapiens OX=9606 GN=CTTN PE=1 SV=2 5.72 2361.7 - 337864 - - - -2.5136 - 1.964 0.307 - 671.5 1 2 0 -0.0027 10 0 0 0 6.14E+06 1.46E+07 - - - 3.1917 0.9996 221125_WJC_METTL3_EV_vs_WT_F04.11788.11788.2 4.11E-05 22-Nov R.LQAQSLSTVGPR.L sp|O43290|SNUT1_HUMAN 1 1255.6885 1.92 46131 11788 2 1255.690869 628.8515 U4\U6.U5 tri-snRNP-associated protein 1 OS=Homo sapiens OX=9606 GN=SART1 PE=1 SV=1 9.75 2362.1 - 2.05E+06 - - - 1.9264 - 2.225 0.433 - 466.6 1 2 0 0.0024 12 0 0 0 2.89E+07 1.50E+07 - - - 4.3427 0.9996 221125_WJC_METTL3_EV_vs_WT_F04.11789.11789.3 5.01E-06 15/48 R.VLEVEKEDTEELR.Q "sp|Q9UKJ3|GPTC8_HUMAN,tr|K7EKU0|K7EKU0_HUMAN" 2 1587.7992 0.97 46132 11789 3 1587.795452 530.2737 G patch domain-containing protein 8 OS=Homo sapiens OX=9606 GN=GPATCH8 PE=1 SV=2 4.14 2362.2 - 1.35E+06 - - - -2.3492 - 2.703 0.461 - 325.9 1 2 1 -0.0037 13 0 0 0 1.73E+07 1.78E+07 - - - 6.3747 0.9999 221125_WJC_METTL3_EV_vs_WT_F04.11791.11791.2 1.53E-05 15/30 K.AFGPGLQGGSAGSPAR.F "sp|P21333|FLNA_HUMAN,tr|Q60FE5|Q60FE5_HUMAN" 2 1428.711 1.15 46134 11791 2 1428.711171 715.3628 Filamin-A OS=Homo sapiens OX=9606 GN=FLNA PE=1 SV=4 9.79 2362.4 - 1.19E+06 - - - 0.1365 - 2.899 0.538 - 417.8 1 2 0 0.0002 16 0 0 0 2.99E+07 2.60E+07 - - - 5.6314 0.9902 221125_WJC_METTL3_EV_vs_WT_F04.11792.11792.2 0.000421 18-Dec Q.PSASLGVGYR.T sp|Q96PK6|RBM14_HUMAN 1 1005.5243 1.7 46135 11792 2 1005.523836 503.7694 RNA-binding protein 14 OS=Homo sapiens OX=9606 GN=RBM14 PE=1 SV=2 9.18 2362.6 - 807464 - - - -0.5052 - 2.384 0.397 - 420.9 1 1 0 -0.0005 10 0 0 0 1.30E+07 7.68E+06 - - - 4.3981 0.9995 221125_WJC_METTL3_EV_vs_WT_F04.11793.11793.3 0.00025 Sep-44 R.AQPSASLGVGYR.T sp|Q96PK6|RBM14_HUMAN 1 1204.62 2.61 46136 11793 3 1204.619172 402.5473 RNA-binding protein 14 OS=Homo sapiens OX=9606 GN=RBM14 PE=1 SV=2 8.79 2362.7 - 793120 - - - -0.7172 - 2.05 0.296 - 85.2 1 2 0 -0.0009 12 0 0 0 1.16E+07 4.45E+06 - - - 3.8296 0.9993 221125_WJC_METTL3_EV_vs_WT_F04.11795.11795.2 0.000797 24-Nov R.AVLSDSPQLSEGK.E "sp|Q7Z4H7|HAUS6_HUMAN,tr|Q5VY60|Q5VY60_HUMAN,tr|Q5SYF9|Q5SYF9_HUMAN" 3 1329.6776 1.26 46138 11795 2 1329.673976 665.8461 HAUS augmin-like complex subunit 6 OS=Homo sapiens OX=9606 GN=HAUS6 PE=1 SV=2 4.37 2362.9 - 426217 - - - -2.733 - 2.117 0.427 - 377.1 1 2 0 -0.0036 13 0 0 0 4.70E+06 3.72E+06 - - - 4.1186 0.9982 221125_WJC_METTL3_EV_vs_WT_F04.11798.11798.2 0.000185 30-Jul R.GPAGDATVASEKESVM.- "sp|Q15758|AAAT_HUMAN,tr|M0QXM4|M0QXM4_HUMAN" 2 1547.7137 2.16 46141 11798 2 1547.713858 774.8641 Neutral amino acid transporter B(0) OS=Homo sapiens OX=9606 GN=SLC1A5 PE=1 SV=2 4.14 2363.3 - 161271 - - - 0.0775 - 1.612 0.561 - 69.6 1 2 1 0.0001 16 0 0 0 1.50E+06 6.93E+05 - - - 4.3584 0.9997 221125_WJC_METTL3_EV_vs_WT_F04.11801.11801.2 0.00136 18-Jul R.GYSFTTTAER.E "sp|P63261|ACTG_HUMAN,sp|P60709|ACTB_HUMAN,tr|A0A804GS07|A0A804GS07_HUMAN,tr|I3L3I0|I3L3I0_HUMAN,tr|E7EVS6|E7EVS6_HUMAN,tr|A0A6Q8PFE4|A0A6Q8PFE4_HUMAN,tr|I3L1U9|I3L1U9_HUMAN,tr|A0A2R8YEA7|A0A2R8YEA7_HUMAN,tr|A0A2R8Y793|A0A2R8Y793_HUMAN,tr|I3L4N8|I3L4N8_HUMAN" 10 1131.5197 0.99 46142 11801 2 1131.519703 566.7671 "Actin, cytoplasmic 2 OS=Homo sapiens OX=9606 GN=ACTG1 PE=1 SV=1" 6 2363.7 - 4.89E+07 - - - 0.0442 - 1.77 0.404 - 159.5 1 2 0 0.0001 10 0 0 0 6.71E+08 6.76E+08 - - - 3.6187 1 221125_WJC_METTL3_EV_vs_WT_F04.11802.11802.3 6.70E-09 16/48 K.VVSQYHELVVQAR.D "sp|Q16891|MIC60_HUMAN,tr|B9A067|B9A067_HUMAN,tr|C9J406|C9J406_HUMAN,tr|H7C463|H7C463_HUMAN" 4 1526.8205 1.32 46143 11802 3 1526.82107 509.9475 MICOS complex subunit MIC60 OS=Homo sapiens OX=9606 GN=IMMT PE=1 SV=1 6.72 2363.8 - 1.95E+06 - - - 0.3563 - 2.979 0.549 - 392.1 1 2 0 0.0005 13 0 0 0 4.28E+08 3.24E+08 - - - 7.6203 0.9998 221125_WJC_METTL3_EV_vs_WT_F04.11803.11803.2 0.000371 18-Jul K.AVDPEDDFQR.E "sp|Q99848|EBP2_HUMAN,tr|H7C2Q8|H7C2Q8_HUMAN" 2 1190.5204 0.98 46144 11803 2 1190.519509 596.2675 Probable rRNA-processing protein EBP2 OS=Homo sapiens OX=9606 GN=EBNA1BP2 PE=1 SV=2 3.84 2363.9 - 1.26E+06 - - - -0.7325 - 1.665 0.563 - 186.7 1 2 0 -0.0009 10 0 0 0 1.08E+07 1.10E+07 - - - 4.6221 0.9996 221125_WJC_METTL3_EV_vs_WT_F04.11808.11808.2 0.00011 24-Oct R.AVLSDSPQLSEGK[136.11].E "sp|Q7Z4H7|HAUS6_HUMAN,tr|Q5VY60|Q5VY60_HUMAN,tr|Q5SYF9|Q5SYF9_HUMAN" 3 1337.6918 1.22 46149 11808 2 1337.695101 669.8532 HAUS augmin-like complex subunit 6 OS=Homo sapiens OX=9606 GN=HAUS6 PE=1 SV=2 4.37 2364.5 - 301692 - - - 2.4602 - 2.211 0.476 - 242.9 1 2 0 0.0033 13 0 0 0 5.57E+06 4.57E+06 - - - 4.5921 0.9986 221125_WJC_METTL3_EV_vs_WT_F04.11810.11810.2 4.41E-05 24-Aug R.VLEVEK[136.11]EDTEELR[166.11].Q "sp|Q9UKJ3|GPTC8_HUMAN,tr|K7EKU0|K7EKU0_HUMAN" 2 1605.8217 0.73 46151 11810 2 1605.820329 803.9181 G patch domain-containing protein 8 OS=Homo sapiens OX=9606 GN=GPATCH8 PE=1 SV=2 4.14 2364.8 - 126001 - - - -0.8239 - 1.971 0.566 - 189 1 2 1 -0.0013 13 0 0 0 6.90E+05 9.41E+05 - - - 4.9626 0.9999 221125_WJC_METTL3_EV_vs_WT_F04.11813.11813.3 0.000248 16/40 R.SLGTADVHFER[166.11].K "sp|Q86V81|THOC4_HUMAN,tr|E9PB61|E9PB61_HUMAN" 2 1240.6076 0.72 46152 11813 3 1240.605564 414.5431 THO complex subunit 4 OS=Homo sapiens OX=9606 GN=ALYREF PE=1 SV=3 5.3 2365.2 - 3.88E+06 - - - -1.6169 - 2.858 0.397 - 328.4 1 2 0 -0.002 11 0 0 0 1.71E+09 2.36E+09 - - - 5.9488 0.9576 221125_WJC_METTL3_EV_vs_WT_F04.11816.11816.2 0.0367 14-Aug N.KTLPVAFK.V "sp|Q13950|RUNX2_HUMAN,sp|Q13761|RUNX3_HUMAN,tr|A0A0D9SEN7|A0A0D9SEN7_HUMAN,tr|A0A2R8Y7Z3|A0A2R8Y7Z3_HUMAN,tr|I3L0L0|I3L0L0_HUMAN,tr|I3L354|I3L354_HUMAN" 6 902.5589 999 46155 11816 2 902.557947 452.2867 Runt-related transcription factor 2 OS=Homo sapiens OX=9606 GN=RUNX2 PE=1 SV=2 10 2365.4 - 1.47E+06 - - - -1.0991 - 1.805 0.276 - 295.7 1 1 0 -0.001 8 0 0 0 2.58E+07 0.00E+00 - - - 2.8603 0.9998 221125_WJC_METTL3_EV_vs_WT_F04.11821.11821.2 5.36E-05 18-Sep R.EWGSGSDTLR[166.11].C "sp|P16615|AT2A2_HUMAN,tr|H7C5W9|H7C5W9_HUMAN" 2 1116.5075 1.62 46160 11821 2 1116.50625 559.261 Sarcoplasmic\endoplasmic reticulum calcium ATPase 2 OS=Homo sapiens OX=9606 GN=ATP2A2 PE=1 SV=1 4.37 2365.9 - 477939 - - - -1.1393 - 1.794 0.473 - 324.9 1 2 0 -0.0013 10 0 0 0 7.57E+06 4.67E+06 - - - 4.1656 0.9986 221125_WJC_METTL3_EV_vs_WT_F04.11822.11822.3 0.000897 Nov-32 K.ELEDFEMKK.A "sp|Q9UG63|ABCF2_HUMAN,tr|C9JZV3|C9JZV3_HUMAN,tr|C9JHK9|C9JHK9_HUMAN" 3 1167.5482 0.38 46161 11822 3 1167.542645 390.19 ATP-binding cassette sub-family F member 2 OS=Homo sapiens OX=9606 GN=ABCF2 PE=1 SV=2 4.41 2366.1 - 435251 - - - -4.7373 - 2.033 0.399 - 159 1 2 0 -0.0055 9 0 0 0 2.58E+06 6.69E+06 - - - 5.1252 0.9995 221125_WJC_METTL3_EV_vs_WT_F04.11823.11823.2 0.00052 16-Oct R.QAVDVSPLR[166.11].R "sp|P46782|RS5_HUMAN,tr|M0QZN2|M0QZN2_HUMAN,tr|M0R0F0|M0R0F0_HUMAN,tr|M0R0R2|M0R0R2_HUMAN" 4 993.5483 1.06 46162 11823 2 993.550053 497.7814 40S ribosomal protein S5 OS=Homo sapiens OX=9606 GN=RPS5 PE=1 SV=4 5.84 2366.2 - 387060 - - - 1.8006 - 1.766 0.437 - 382.7 1 2 0 0.0018 9 0 0 0 9.65E+06 9.14E+06 - - - 3.9134 1 221125_WJC_METTL3_EV_vs_WT_F04.11825.11825.2 1.86E-11 17/24 K.VVSQYHELVVQAR[166.11].D "sp|Q16891|MIC60_HUMAN,tr|B9A067|B9A067_HUMAN,tr|C9J406|C9J406_HUMAN,tr|H7C463|H7C463_HUMAN" 4 1536.8288 1.43 46164 11825 2 1536.823144 769.4217 MICOS complex subunit MIC60 OS=Homo sapiens OX=9606 GN=IMMT PE=1 SV=1 6.72 2366.5 - 290255 - - - -3.6777 - 3.018 0.671 - 1116.4 1 2 0 -0.0057 13 0 0 0 2.79E+07 1.94E+07 - - - 6.8302 1 221125_WJC_METTL3_EV_vs_WT_F04.11831.11831.3 3.66E-07 14/48 K.VVSQYHELVVQAR[166.11].D "sp|Q16891|MIC60_HUMAN,tr|B9A067|B9A067_HUMAN,tr|C9J406|C9J406_HUMAN,tr|H7C463|H7C463_HUMAN" 4 1536.8288 1.32 46168 11831 3 1536.827071 513.2835 MICOS complex subunit MIC60 OS=Homo sapiens OX=9606 GN=IMMT PE=1 SV=1 6.72 2367.1 - 1.64E+07 - - - -1.1224 - 2.59 0.565 - 314.7 1 2 0 -0.0017 13 0 0 0 4.28E+08 3.24E+08 - - - 7.4189 0.9938 221125_WJC_METTL3_EV_vs_WT_F04.11832.11832.2 1.37E-06 20-Dec S.GSGSGTDFTLK.L "sp|A2NJV5|KV229_HUMAN,sp|A0A087WW87|KV240_HUMAN,sp|P06310|KV230_HUMAN,sp|A0A075B6S2|KVD29_HUMAN,sp|P01614|KVD40_HUMAN,sp|P01615|KVD28_HUMAN,sp|A0A075B6S6|KVD30_HUMAN,sp|A0A075B6P5|KV228_HUMAN,sp|A0A0A0MRZ7|KVD26_HUMAN" 9 1068.5088 86.09 46169 11832 2 1068.507591 535.2617 Immunoglobulin kappa variable 2-29 OS=Homo sapiens OX=9606 GN=IGKV2-29 PE=3 SV=2 5.84 2367.2 - 2.66E+06 - - - -1.0884 - 2.534 0.558 - 551.5 1 1 0 -0.0012 11 0 0 0 3.90E+07 4.53E+05 - - - 5.6773 0.9999 221125_WJC_METTL3_EV_vs_WT_F04.11833.11833.2 0.000294 20-Dec R.SLGTADVHFER[166.11].K "sp|Q86V81|THOC4_HUMAN,tr|E9PB61|E9PB61_HUMAN" 2 1240.6076 0.71 46170 11833 2 1240.607389 621.3111 THO complex subunit 4 OS=Homo sapiens OX=9606 GN=ALYREF PE=1 SV=3 5.3 2367.3 - 1.83E+06 - - - -0.1459 - 2.358 0.538 - 436.1 1 2 0 -0.0002 11 0 0 0 1.72E+08 2.43E+08 - - - 5.3352 0.9998 221125_WJC_METTL3_EV_vs_WT_F04.11835.11835.2 0.000572 20-Aug K.EAAENSLVAYK.A "sp|P62258|1433E_HUMAN,tr|K7EM20|K7EM20_HUMAN" 2 1193.5928 1.07 46172 11835 2 1193.593898 597.8037 14-3-3 protein epsilon OS=Homo sapiens OX=9606 GN=YWHAE PE=1 SV=1 4.53 2367.6 - 884713 - - - 0.9048 - 1.894 0.452 - 235 1 2 0 0.0011 11 0 0 0 6.02E+07 5.63E+07 - - - 4.1069 1 221125_WJC_METTL3_EV_vs_WT_F04.11836.11836.2 2.21E-05 18/24 K.VVSQYHELVVQAR.D "sp|Q16891|MIC60_HUMAN,tr|B9A067|B9A067_HUMAN,tr|C9J406|C9J406_HUMAN,tr|H7C463|H7C463_HUMAN" 4 1526.8205 1.43 46173 11836 2 1526.819 764.4175 MICOS complex subunit MIC60 OS=Homo sapiens OX=9606 GN=IMMT PE=1 SV=1 6.72 2367.7 - 864627 - - - -0.9995 - 3.267 0.605 - 1517.5 1 2 0 -0.0015 13 0 0 0 2.79E+07 1.94E+07 - - - 6.5475 0.9993 221125_WJC_METTL3_EV_vs_WT_F04.11837.11837.2 0.181 18-Oct R.VPAPFKPITR.K "sp|Q9NX20|RM16_HUMAN,tr|E9PI14|E9PI14_HUMAN" 2 1124.6706 0.76 46174 11837 2 1124.669706 563.3426 "39S ribosomal protein L16, mitochondrial OS=Homo sapiens OX=9606 GN=MRPL16 PE=1 SV=1" 11 2367.8 - 690383 - - - -0.8082 - 2.01 0.237 - 365.4 1 2 0 -0.0009 10 0 0 0 1.14E+07 1.51E+07 - - - 2.7399 1 221125_WJC_METTL3_EV_vs_WT_F04.11841.11841.2 1.38E-07 13/24 K.AGLENTVAETEC[160.03]R.Y "sp|P13646|K1C13_HUMAN,tr|K7ERE3|K7ERE3_HUMAN" 2 1448.6566 30.06 46178 11841 2 1448.653335 725.3356 "Keratin, type I cytoskeletal 13 OS=Homo sapiens OX=9606 GN=KRT13 PE=1 SV=4" 4.25 2368.3 - 596132 - - - -2.2241 - 2.884 0.601 - 597.4 1 2 0 -0.0032 13 0 0 0 1.46E+07 4.85E+05 - - - 6.1974 0.9953 221125_WJC_METTL3_EV_vs_WT_F04.11842.11842.2 0.0322 20-Sep K.GPQPPTVSPIR[166.11].S sp|P46087|NOP2_HUMAN 1 1157.6432 0.39 46179 11842 2 1157.641407 579.8289 Probable 28S rRNA (cytosine(4447)-C(5))-methyltransferase OS=Homo sapiens OX=9606 GN=NOP2 PE=1 SV=2 9.75 2368.5 - 432344 - - - -1.5722 - 1.422 0.205 - 179.7 1 2 0 -0.0018 11 0 0 0 7.07E+06 1.81E+07 - - - 1.507 0.9914 221125_WJC_METTL3_EV_vs_WT_F04.11846.11846.2 0.000508 16-Dec L.GTADVHFER[166.11].K "sp|Q86V81|THOC4_HUMAN,tr|E9PB61|E9PB61_HUMAN" 2 1040.4915 0.75 46182 11846 2 1040.490708 521.253 THO complex subunit 4 OS=Homo sapiens OX=9606 GN=ALYREF PE=1 SV=3 5.32 2368.9 - 9.26E+06 - - - -0.74 - 2.109 0.474 - 900.9 1 1 0 -0.0008 9 0 0 0 2.76E+08 3.69E+08 - - - 4.7006 0.9999 221125_WJC_METTL3_EV_vs_WT_F04.11848.11848.2 0.000229 20-Nov R.SLGTADVHFER.K "sp|Q86V81|THOC4_HUMAN,tr|E9PB61|E9PB61_HUMAN" 2 1230.5993 0.71 46183 11848 2 1230.597501 616.3069 THO complex subunit 4 OS=Homo sapiens OX=9606 GN=ALYREF PE=1 SV=3 5.3 2369.2 - 3.97E+06 - - - -1.4619 - 2.397 0.534 - 358.5 1 2 0 -0.0018 11 0 0 0 1.72E+08 2.43E+08 - - - 5.3495 0.9996 221125_WJC_METTL3_EV_vs_WT_F04.11851.11851.2 0.0109 18-Dec K.YEELQVTAGR.H "sp|P48668|K2C6C_HUMAN,sp|O95678|K2C75_HUMAN,sp|P02538|K2C6A_HUMAN" 3 1164.5775 462.37 46186 11851 2 1164.574961 583.296 "Keratin, type II cytoskeletal 6C OS=Homo sapiens OX=9606 GN=KRT6C PE=1 SV=3" 4.53 2369.5 - 1.36E+06 - - - -2.1819 - 2.269 0.417 - 588.9 1 2 0 -0.0025 10 0 0 0 6.84E+08 1.48E+06 - - - 4.4072 0.9988 221125_WJC_METTL3_EV_vs_WT_F04.11853.11853.2 0.0497 22-Oct K.ETGGILGEGTPK.E "sp|Q96S66|CLCC1_HUMAN,tr|A0A6Q8PEZ7|A0A6Q8PEZ7_HUMAN,tr|A0A6Q8PG30|A0A6Q8PG30_HUMAN,tr|A0A6Q8PFF7|A0A6Q8PFF7_HUMAN,tr|A0A6Q8PHQ1|A0A6Q8PHQ1_HUMAN,tr|A0A6Q8PGA4|A0A6Q8PGA4_HUMAN,tr|A0A6Q8PG14|A0A6Q8PG14_HUMAN,tr|A0A6Q8PG75|A0A6Q8PG75_HUMAN" 8 1157.5928 8.66 46188 11853 2 1157.591606 579.8037 Chloride channel CLIC-like protein 1 OS=Homo sapiens OX=9606 GN=CLCC1 PE=1 SV=1 4.53 2369.7 - 715090 - - - -1.047 - 1.384 0.339 - 191.7 1 2 0 -0.0012 12 0 0 0 9.81E+06 1.13E+06 - - - 2.3995 0.9999 221125_WJC_METTL3_EV_vs_WT_F04.11854.11854.3 5.40E-05 13/40 K.EVQGISEHYLR.R "sp|Q8IZH2|XRN1_HUMAN,tr|H7C5E4|H7C5E4_HUMAN" 2 1329.6677 1.59 46189 11854 3 1329.664251 444.2298 5'-3' exoribonuclease 1 OS=Homo sapiens OX=9606 GN=XRN1 PE=1 SV=1 5.4 2369.9 - 683958 - - - -2.6044 - 2.587 0.461 - 316.3 1 2 0 -0.0035 11 0 0 0 1.69E+07 1.06E+07 - - - 6.3789 0.9995 221125_WJC_METTL3_EV_vs_WT_F04.11855.11855.2 0.0103 22-Nov K.LEAEGVPEVSEK[136.11].Y sp|O76003|GLRX3_HUMAN 1 1293.6544 0.78 46190 11855 2 1293.652501 647.8345 Glutaredoxin-3 OS=Homo sapiens OX=9606 GN=GLRX3 PE=1 SV=2 4.09 2370 - 561765 - - - -1.4386 - 2.17 0.334 - 424.2 1 2 0 -0.0019 12 0 0 0 1.24E+07 1.59E+07 - - - 3.5458 0.9998 221125_WJC_METTL3_EV_vs_WT_F04.11857.11857.3 0.00302 Dec-44 R.AQPSASLGVGYR[166.11].T sp|Q96PK6|RBM14_HUMAN 1 1214.6283 0.31 46192 11857 3 1214.630928 405.8834 RNA-binding protein 14 OS=Homo sapiens OX=9606 GN=RBM14 PE=1 SV=2 8.79 2370.2 - 491096 - - - 2.1587 - 2.216 0.39 - 131.1 1 2 0 0.0026 12 0 0 0 1.20E+07 3.81E+07 - - - 5.093 1 221125_WJC_METTL3_EV_vs_WT_F04.11859.11859.2 2.78E-08 13/26 R.EALENANTNTEVLK.N sp|Q9H444|CHM4B_HUMAN 1 1544.7682 1.72 46194 11859 2 1544.765236 773.3914 Charged multivesicular body protein 4b OS=Homo sapiens OX=9606 GN=CHMP4B PE=1 SV=1 4.25 2370.5 - 374086 - - - -1.9291 - 2.831 0.593 - 628.1 1 2 0 -0.003 14 0 0 0 2.96E+06 1.72E+06 - - - 6.0314 0.999 221125_WJC_METTL3_EV_vs_WT_F04.11860.11860.2 0.0204 20-Sep R.VLVDQTTGLSR.G sp|Q15717|ELAV1_HUMAN 1 1187.651 2.04 46195 11860 2 1187.649374 594.8328 ELAV-like protein 1 OS=Homo sapiens OX=9606 GN=ELAVL1 PE=1 SV=2 5.81 2370.6 - 317669 - - - -1.3699 - 1.56 0.339 - 206.7 1 2 0 -0.0016 11 0 0 0 2.05E+07 1.00E+07 - - - 2.7473 0.9998 221125_WJC_METTL3_EV_vs_WT_F04.11863.11863.2 6.29E-05 18-Oct R.GYSFTTTAER[166.11].E "sp|P63261|ACTG_HUMAN,sp|P60709|ACTB_HUMAN,tr|A0A804GS07|A0A804GS07_HUMAN,tr|I3L3I0|I3L3I0_HUMAN,tr|E7EVS6|E7EVS6_HUMAN,tr|A0A6Q8PFE4|A0A6Q8PFE4_HUMAN,tr|I3L1U9|I3L1U9_HUMAN,tr|A0A2R8YEA7|A0A2R8YEA7_HUMAN,tr|A0A2R8Y793|A0A2R8Y793_HUMAN,tr|I3L4N8|I3L4N8_HUMAN" 10 1141.5279 0.99 46197 11863 2 1141.526317 571.7712 "Actin, cytoplasmic 2 OS=Homo sapiens OX=9606 GN=ACTG1 PE=1 SV=1" 6 2371 - 1.68E+07 - - - -1.4069 - 1.997 0.487 - 378.5 1 2 0 -0.0016 10 0 0 0 6.73E+08 6.77E+08 - - - 4.5681 0.9994 221125_WJC_METTL3_EV_vs_WT_F04.11864.11864.2 0.00201 18-Sep R.GGPISFSSSR.S sp|P35580|MYH10_HUMAN 1 993.488 0.97 46198 11864 2 993.489691 497.7513 Myosin-10 OS=Homo sapiens OX=9606 GN=MYH10 PE=1 SV=3 9.75 2371.1 - 1.95E+06 - - - 1.7434 - 1.701 0.424 - 292.1 1 2 0 0.0017 10 0 0 0 3.33E+07 3.42E+07 - - - 3.6549 0.9812 221125_WJC_METTL3_EV_vs_WT_F04.11865.11865.2 7.23E-06 18-Dec S.LGTADVHFER[166.11].K "sp|Q86V81|THOC4_HUMAN,tr|E9PB61|E9PB61_HUMAN" 2 1153.5755 1.05 46199 11865 2 1153.572478 577.795 THO complex subunit 4 OS=Homo sapiens OX=9606 GN=ALYREF PE=1 SV=3 5.32 2371.2 - 1.35E+06 - - - -2.6561 - 2.601 0.501 - 780.3 1 1 0 -0.0031 10 0 0 0 2.31E+07 2.20E+07 - - - 5.4086 0.9999 221125_WJC_METTL3_EV_vs_WT_F04.11866.11866.2 8.06E-05 18-Dec K.EMEQLVLDK[136.11]K[136.11].Q sp|Q96A49|SYAP1_HUMAN 1 1247.6766 1.11 46200 11866 2 1247.676075 624.8456 Synapse-associated protein 1 OS=Homo sapiens OX=9606 GN=SYAP1 PE=1 SV=1 4.68 2371.3 - 1.20E+06 - - - -0.44 - 2.289 0.54 - 741.3 1 2 0 -0.0006 10 0 0 0 8.74E+07 7.91E+07 - - - 5.3408 0.9999 221125_WJC_METTL3_EV_vs_WT_F04.11867.11867.3 2.91E-07 16/40 R.ILVLDDTNHER[166.11].E "sp|P09543|CN37_HUMAN,tr|C9K0L8|C9K0L8_HUMAN,tr|K7ERZ0|K7ERZ0_HUMAN,tr|K7ERC4|K7ERC4_HUMAN,tr|K7EN66|K7EN66_HUMAN" 5 1333.6865 0.72 46201 11867 3 1333.682651 445.5695 "2',3'-cyclic-nucleotide 3'-phosphodiesterase OS=Homo sapiens OX=9606 GN=CNP PE=1 SV=2" 4.54 2371.4 - 1.07E+06 - - - -2.9227 - 2.402 0.55 - 410.2 1 2 0 -0.0039 11 0 0 0 4.31E+07 5.96E+07 - - - 7.1603 0.9805 221125_WJC_METTL3_EV_vs_WT_F04.11868.11868.2 0.000397 14-Oct G.TADVHFER.K "sp|Q86V81|THOC4_HUMAN,tr|E9PB61|E9PB61_HUMAN" 2 973.4617 0.76 46202 11868 2 973.460272 487.7381 THO complex subunit 4 OS=Homo sapiens OX=9606 GN=ALYREF PE=1 SV=3 5.29 2371.5 - 1.03E+06 - - - -1.5121 - 1.891 0.412 - 551 1 1 0 -0.0015 8 0 0 0 1.55E+07 2.04E+07 - - - 4.0051 0.9998 221125_WJC_METTL3_EV_vs_WT_F04.11869.11869.2 6.31E-07 18-Sep R.EIC[160.03]C[160.03]YSISC[160.03]K.E "sp|Q96BM9|ARL8A_HUMAN,sp|Q9NVJ2|ARL8B_HUMAN" 2 1318.5356 1.23 46203 11869 2 1318.532573 660.2751 ADP-ribosylation factor-like protein 8A OS=Homo sapiens OX=9606 GN=ARL8A PE=1 SV=1 6.07 2371.6 - 657200 - - - -2.2806 - 1.922 0.643 - 362.6 1 2 0 -0.003 10 0 0 0 9.24E+06 7.49E+06 - - - 5.613 0.9999 221125_WJC_METTL3_EV_vs_WT_F04.11872.11872.2 4.39E-05 17/34 K.LAALGGGAGPGAAEPEQR.V sp|Q4KMQ1|TPRN_HUMAN 1 1620.822 3.05 46206 11872 2 1620.820985 811.4183 Taperin OS=Homo sapiens OX=9606 GN=TPRN PE=1 SV=2 4.53 2372 - 454131 - - - -0.6157 - 2.771 0.52 - 402.1 1 2 0 -0.001 18 0 0 0 7.77E+06 2.55E+06 - - - 5.3872 0.9997 221125_WJC_METTL3_EV_vs_WT_F04.11876.11876.3 0.00918 Oct-44 K.GLGHPPSSPLLK.K "sp|O95785|WIZ_HUMAN,tr|A0A669KBG4|A0A669KBG4_HUMAN,tr|A0A2R8YFV2|A0A2R8YFV2_HUMAN,tr|A0A669KAV7|A0A669KAV7_HUMAN,tr|M0QXA7|M0QXA7_HUMAN,tr|A0A669KBH9|A0A669KBH9_HUMAN,tr|B9EGQ5|B9EGQ5_HUMAN" 7 1201.6819 1.73 46208 11876 3 1201.679468 401.5679 Protein Wiz OS=Homo sapiens OX=9606 GN=WIZ PE=1 SV=2 8.76 2372.4 - 1.16E+06 - - - -2.0305 - 1.869 0.398 - 83.5 1 2 0 -0.0024 12 0 0 0 1.38E+07 8.00E+06 - - - 4.7102 0.9994 221125_WJC_METTL3_EV_vs_WT_F04.11877.11877.3 0.000333 15/40 R.ILVLDDTNHER.E "sp|P09543|CN37_HUMAN,tr|C9K0L8|C9K0L8_HUMAN,tr|K7ERZ0|K7ERZ0_HUMAN,tr|K7ERC4|K7ERC4_HUMAN,tr|K7EN66|K7EN66_HUMAN" 5 1323.6783 0.69 46209 11877 3 1323.675245 442.2334 "2',3'-cyclic-nucleotide 3'-phosphodiesterase OS=Homo sapiens OX=9606 GN=CNP PE=1 SV=2" 4.54 2372.5 - 961386 - - - -2.2921 - 2.187 0.316 - 379.7 1 2 0 -0.003 11 0 0 0 4.35E+07 6.33E+07 - - - 4.2853 1 221125_WJC_METTL3_EV_vs_WT_F04.11878.11878.2 9.70E-07 16/24 R.TIVITSHPGQIVK[136.11].H sp|P31689|DNJA1_HUMAN 1 1399.8278 0.43 46210 11878 2 1399.824448 700.9212 DnaJ homolog subfamily A member 1 OS=Homo sapiens OX=9606 GN=DNAJA1 PE=1 SV=2 8.44 2372.7 - 1.11E+06 - - - -2.4303 - 2.785 0.583 - 736.6 1 2 0 -0.0034 13 0 0 0 1.64E+07 3.79E+07 - - - 5.9747 0.9999 221125_WJC_METTL3_EV_vs_WT_F04.11879.11879.2 0.000148 14/18 K.QAITQVVVSR[166.11].L sp|Q9H9B4|SFXN1_HUMAN 1 1109.6432 0.91 46211 11879 2 1109.643496 555.8289 Sideroflexin-1 OS=Homo sapiens OX=9606 GN=SFXN1 PE=1 SV=4 9.75 2372.8 - 705645 - - - 0.2424 - 2.687 0.398 - 811.7 1 2 0 0.0003 10 0 0 0 2.51E+07 2.77E+07 - - - 4.7395 0.9954 221125_WJC_METTL3_EV_vs_WT_F04.11881.11881.2 0.00141 22-Aug R.YVGFGNTPPPQK[136.11].K "sp|Q8N6T3|ARFG1_HUMAN,tr|F8VWH9|F8VWH9_HUMAN,tr|E5RHT6|E5RHT6_HUMAN,tr|F8W1U7|F8W1U7_HUMAN,tr|E5RHC5|E5RHC5_HUMAN" 5 1311.6703 2.29 46213 11881 2 1311.675339 656.8424 ADP-ribosylation factor GTPase-activating protein 1 OS=Homo sapiens OX=9606 GN=ARFGAP1 PE=1 SV=2 8.59 2373.1 - 445858 - - - 3.8516 - 1.437 0.4 - 123.5 1 2 0 0.0051 12 0 0 0 1.20E+07 5.26E+06 - - - 2.9478 1 221125_WJC_METTL3_EV_vs_WT_F04.11882.11882.2 4.38E-05 22-Nov R.TLVDNAYSC[160.03]DPR[166.11].L "sp|Q99543|DNJC2_HUMAN,tr|H7C3L7|H7C3L7_HUMAN" 2 1419.6328 0.55 46214 11882 2 1419.627644 710.8237 DnaJ homolog subfamily C member 2 OS=Homo sapiens OX=9606 GN=DNAJC2 PE=1 SV=4 4.21 2373.2 - 365221 - - - -3.6312 - 2.198 0.636 - 292.6 1 2 0 -0.0052 12 0 0 0 2.71E+06 4.92E+06 - - - 5.809 0.9997 221125_WJC_METTL3_EV_vs_WT_F04.11885.11885.2 0.000166 22-Dec R.INVYYNEAAGNK.Y sp|Q13885|TBB2A_HUMAN 1 1354.6517 1.12 46215 11885 2 1354.648387 678.3331 Tubulin beta-2A chain OS=Homo sapiens OX=9606 GN=TUBB2A PE=1 SV=1 6 2373.6 - 1.61E+06 - - - -2.4678 - 2.628 0.489 - 426.2 1 2 0 -0.0033 12 0 0 0 1.90E+07 1.70E+07 - - - 5.194 0.9968 221125_WJC_METTL3_EV_vs_WT_F04.11887.11887.3 5.46E-05 14/36 S.LGTADVHFER[166.11].K "sp|Q86V81|THOC4_HUMAN,tr|E9PB61|E9PB61_HUMAN" 2 1153.5755 0.81 46217 11887 3 1153.574481 385.5325 THO complex subunit 4 OS=Homo sapiens OX=9606 GN=ALYREF PE=1 SV=3 5.32 2373.7 - 1.17E+06 - - - -0.9197 - 2.501 0.471 - 259 1 1 0 -0.0011 10 0 0 0 9.51E+06 1.18E+07 - - - 6.468 0.999 221125_WJC_METTL3_EV_vs_WT_F04.11889.11889.2 0.00158 20-Oct K.EVDYSDSLTEK[136.11].Q "sp|P51532|SMCA4_HUMAN,tr|A0A2R8Y5K3|A0A2R8Y5K3_HUMAN,tr|A0A2R8Y7S2|A0A2R8Y7S2_HUMAN,tr|A0A2R8Y7F3|A0A2R8Y7F3_HUMAN,tr|A0A2R8YGG3|A0A2R8YGG3_HUMAN,tr|A0A2R8Y523|A0A2R8Y523_HUMAN,tr|A0A2R8Y6V2|A0A2R8Y6V2_HUMAN,tr|Q9HBD4|Q9HBD4_HUMAN,tr|K7EQF0|K7EQF0_HUMAN,tr|A0A2R8Y440|A0A2R8Y440_HUMAN,tr|A0A2R8YFK5|A0A2R8YFK5_HUMAN,tr|A0A2R8YDA1|A0A2R8YDA1_HUMAN,tr|A0A2R8Y7Y7|A0A2R8Y7Y7_HUMAN,tr|A0A2R8YF58|A0A2R8YF58_HUMAN,tr|A0A2R8Y526|A0A2R8Y526_HUMAN,tr|K7EP28|K7EP28_HUMAN,tr|A0A2R8YG32|A0A2R8YG32_HUMAN,tr|A0A2R8Y6N0|A0A2R8Y6N0_HUMAN,tr|A0A2R8YF80|A0A2R8YF80_HUMAN,tr|A0A2R8Y4P4|A0A2R8Y4P4_HUMAN,tr|A0A2R8Y4C5|A0A2R8Y4C5_HUMAN" 21 1292.5863 0.31 46219 11889 2 1292.583325 647.3004 Transcription activator BRG1 OS=Homo sapiens OX=9606 GN=SMARCA4 PE=1 SV=2 3.92 2374 - 1.08E+06 - - - -2.3341 - 1.724 0.388 - 176.5 1 2 0 -0.003 11 0 0 0 3.66E+06 1.17E+07 - - - 3.3792 1 221125_WJC_METTL3_EV_vs_WT_F04.11890.11890.2 1.12E-07 22-Dec K.FYEDNGQLDDAR.V sp|Q9HCS7|SYF1_HUMAN 1 1441.611 2.29 46220 11890 2 1441.609231 721.8128 Pre-mRNA-splicing factor SYF1 OS=Homo sapiens OX=9606 GN=XAB2 PE=1 SV=2 3.84 2374.1 - 825102 - - - -1.2181 - 2.463 0.648 - 522.4 1 2 0 -0.0018 12 0 0 0 1.22E+07 5.35E+06 - - - 6.1983 0.9999 221125_WJC_METTL3_EV_vs_WT_F04.11891.11891.2 5.38E-06 13/24 R.TIVITSHPGQIVK.H sp|P31689|DNJA1_HUMAN 1 1391.8137 0.43 46221 11891 2 1391.813238 696.9141 DnaJ homolog subfamily A member 1 OS=Homo sapiens OX=9606 GN=DNAJA1 PE=1 SV=2 8.44 2374.2 - 672753 - - - -0.296 - 2.446 0.581 - 273 1 2 0 -0.0004 13 0 0 0 1.64E+07 3.79E+07 - - - 5.6278 0.994 221125_WJC_METTL3_EV_vs_WT_F04.11893.11893.2 3.84E-06 16-Nov E.MEQLVLDK[136.11]K[136.11].Q sp|Q96A49|SYAP1_HUMAN 1 1118.634 0.85 46223 11893 2 1118.633345 560.3243 Synapse-associated protein 1 OS=Homo sapiens OX=9606 GN=SYAP1 PE=1 SV=1 5.82 2374.5 - 442839 - - - -0.6132 - 2.258 0.533 - 592.4 1 1 0 -0.0007 9 0 0 0 6.04E+06 7.10E+06 - - - 5.3339 0.9909 221125_WJC_METTL3_EV_vs_WT_F04.11896.11896.3 0.0343 Nov-44 R.AVGIWHC[160.03]GSC[160.03]MK[136.11].T "sp|P61513|RL37A_HUMAN,tr|E9PEL3|E9PEL3_HUMAN,tr|C9J4Z3|C9J4Z3_HUMAN,tr|M0R2L6|M0R2L6_HUMAN,tr|M0R0A1|M0R0A1_HUMAN,tr|Q6P4E4|Q6P4E4_HUMAN" 6 1412.6243 0.94 46224 11896 3 1412.622447 471.882 60S ribosomal protein L37a OS=Homo sapiens OX=9606 GN=RPL37A PE=1 SV=2 8.11 2374.9 - 2.17E+06 - - - -1.299 - 1.347 0.232 - 59.6 1 2 0 -0.0018 12 0 0 0 2.87E+07 3.07E+07 - - - 1.9517 0.9906 221125_WJC_METTL3_EV_vs_WT_F04.11897.11897.2 1.35E-05 18-Dec S.LGTADVHFER.K "sp|Q86V81|THOC4_HUMAN,tr|E9PB61|E9PB61_HUMAN" 2 1143.5673 1.11 46225 11897 2 1143.568532 572.7909 THO complex subunit 4 OS=Homo sapiens OX=9606 GN=ALYREF PE=1 SV=3 5.32 2375 - 1.32E+06 - - - 1.1018 - 2.365 0.477 - 473.4 1 1 0 0.0013 10 0 0 0 2.42E+07 2.19E+07 - - - 4.9664 0.9691 221125_WJC_METTL3_EV_vs_WT_F04.11898.11898.3 0.149 Sep-40 K.LK[136.11]PGDLVGVNK[136.11].D "sp|P17980|PRS6A_HUMAN,tr|R4GNH3|R4GNH3_HUMAN,tr|E9PMD8|E9PMD8_HUMAN,tr|E9PKD5|E9PKD5_HUMAN,tr|E9PLG2|E9PLG2_HUMAN,tr|E9PM69|E9PM69_HUMAN" 6 1154.6994 1.22 46226 11898 3 1154.698247 385.9071 26S proteasome regulatory subunit 6A OS=Homo sapiens OX=9606 GN=PSMC3 PE=1 SV=3 8.59 2375.1 - 1.33E+06 - - - -1.0063 - 1.252 0.176 - 76.3 1 2 0 -0.0012 11 0 0 0 2.57E+07 2.10E+07 - - - 1.1404 0.9907 221125_WJC_METTL3_EV_vs_WT_F04.11899.11899.3 0.137 Aug-32 K.VPDFSEYR[166.11]R[166.11].L "sp|P0C7P4|UCRIL_HUMAN,sp|P47985|UCRI_HUMAN" 2 1187.5838 1.42 46227 11899 3 1187.584431 396.8685 Putative cytochrome b-c1 complex subunit Rieske-like protein 1 OS=Homo sapiens OX=9606 GN=UQCRFS1P1 PE=5 SV=1 6.04 2375.1 - 328660 - - - 0.5212 - 1.385 0.209 - 81.4 1 2 0 0.0006 9 0 0 0 6.60E+06 4.64E+06 - - - 1.8516 0.9995 221125_WJC_METTL3_EV_vs_WT_F04.11900.11900.2 0.000569 Nov-34 K.LAALGGGAGPGAAEPEQR[166.11].V sp|Q4KMQ1|TPRN_HUMAN 1 1630.8303 3.05 46228 11900 2 1630.825611 816.4224 Taperin OS=Homo sapiens OX=9606 GN=TPRN PE=1 SV=2 4.53 2375.3 - 164669 - - - -2.8464 - 2.436 0.492 - 408.1 1 2 0 -0.0046 18 0 0 0 7.77E+06 2.55E+06 - - - 4.8624 0.9911 221125_WJC_METTL3_EV_vs_WT_F04.11904.11904.2 0.000451 14/20 L.VITSHPGQIVK[136.11].H sp|P31689|DNJA1_HUMAN 1 1185.6961 0.4 46230 11904 2 1185.694944 593.8553 DnaJ homolog subfamily A member 1 OS=Homo sapiens OX=9606 GN=DNAJA1 PE=1 SV=2 8.73 2375.8 - 2.19E+06 - - - -0.9817 - 2.462 0.447 - 600.4 1 1 0 -0.0012 11 0 0 0 8.93E+06 2.23E+07 - - - 4.7795 0.9962 221125_WJC_METTL3_EV_vs_WT_F04.11905.11905.3 0.00355 14/56 K.DVDSAYMNKVELQAK.V sp|P12035|K2C3_HUMAN 1 1709.8294 4.84 46231 11905 3 1709.827371 570.9504 "Keratin, type II cytoskeletal 3 OS=Homo sapiens OX=9606 GN=KRT3 PE=1 SV=3" 4.56 2375.9 - 1.60E+06 - - - -1.2077 - 1.836 0.304 - 87.9 1 2 1 -0.0021 15 0 0 0 2.01E+07 4.16E+06 - - - 3.5142 0.9995 221125_WJC_METTL3_EV_vs_WT_F04.11906.11906.2 0.000248 22-Oct K.LEAEGVPEVSEK.Y sp|O76003|GLRX3_HUMAN 1 1285.6402 0.48 46232 11906 2 1285.637726 643.8274 Glutaredoxin-3 OS=Homo sapiens OX=9606 GN=GLRX3 PE=1 SV=2 4.09 2376 - 963886 - - - -1.8948 - 2.023 0.402 - 346.2 1 2 0 -0.0024 12 0 0 0 1.41E+07 2.95E+07 - - - 3.8633 0.9997 221125_WJC_METTL3_EV_vs_WT_F04.11909.11909.2 0.000291 20-Dec R.ILVLDDTNHER[166.11].E "sp|P09543|CN37_HUMAN,tr|C9K0L8|C9K0L8_HUMAN,tr|K7ERZ0|K7ERZ0_HUMAN,tr|K7ERC4|K7ERC4_HUMAN,tr|K7EN66|K7EN66_HUMAN" 5 1333.6865 0.53 46235 11909 2 1333.683032 667.8506 "2',3'-cyclic-nucleotide 3'-phosphodiesterase OS=Homo sapiens OX=9606 GN=CNP PE=1 SV=2" 4.54 2376.4 - 558511 - - - -2.6371 - 2.309 0.539 - 545.7 1 2 0 -0.0035 11 0 0 0 3.69E+06 6.96E+06 - - - 5.2847 0.9453 221125_WJC_METTL3_EV_vs_WT_F04.11910.11910.2 0.00388 18-Dec V.ITSHPGQIVK[136.11].H sp|P31689|DNJA1_HUMAN 1 1086.6277 4.72 46236 11910 2 1086.630838 544.3211 DnaJ homolog subfamily A member 1 OS=Homo sapiens OX=9606 GN=DNAJA1 PE=1 SV=2 8.76 2376.5 - 401913 - - - 2.8934 - 2.235 0.357 - 418.2 1 1 0 0.0031 10 0 0 0 1.76E+07 3.72E+06 - - - 3.9217 0.9998 221125_WJC_METTL3_EV_vs_WT_F04.11911.11911.2 8.62E-06 22-Jul R.TLVDNAYSC[160.03]DPR.L "sp|Q99543|DNJC2_HUMAN,tr|H7C3L7|H7C3L7_HUMAN" 2 1409.6245 0.55 46237 11911 2 1409.624775 705.8195 DnaJ homolog subfamily C member 2 OS=Homo sapiens OX=9606 GN=DNAJC2 PE=1 SV=4 4.21 2376.6 - 332540 - - - 0.1745 - 1.541 0.552 - 110.8 1 2 0 0.0002 12 0 0 0 2.71E+06 4.92E+06 - - - 4.2558 0.9999 221125_WJC_METTL3_EV_vs_WT_F04.11913.11913.2 6.15E-07 13/22 R.INVYYNEAAGNK[136.11].Y sp|Q13885|TBB2A_HUMAN 1 1362.6659 1.12 46238 11913 2 1362.665245 682.3402 Tubulin beta-2A chain OS=Homo sapiens OX=9606 GN=TUBB2A PE=1 SV=1 6 2376.8 - 1.92E+06 - - - -0.5027 - 2.552 0.566 - 571 1 2 0 -0.0007 12 0 0 0 1.90E+07 1.70E+07 - - - 5.6863 0.9998 221125_WJC_METTL3_EV_vs_WT_F04.11915.11915.2 0.0276 14/24 R.ALGQNPTNAEVLK.V "sp|P14649|MYL6B_HUMAN,sp|P60660|MYL6_HUMAN,tr|F8W1R7|F8W1R7_HUMAN,tr|G3V1V0|G3V1V0_HUMAN,tr|B7Z6Z4|B7Z6Z4_HUMAN,tr|G8JLA2|G8JLA2_HUMAN,tr|F8W1I5|F8W1I5_HUMAN,tr|J3KND3|J3KND3_HUMAN,tr|F8VPF3|F8VPF3_HUMAN" 9 1353.7252 1.57 46239 11915 2 1353.725436 677.8699 Myosin light chain 6B OS=Homo sapiens OX=9606 GN=MYL6B PE=1 SV=1 6.05 2377.1 - 2.87E+06 - - - 0.1529 - 2.534 0.356 - 663.3 1 2 0 0.0002 13 0 0 0 1.31E+08 8.38E+07 - - - 4.0567 0.9998 221125_WJC_METTL3_EV_vs_WT_F04.11916.11916.2 4.08E-06 24-Dec R.ALGQNPTNAEVLK[136.11].V "sp|P14649|MYL6B_HUMAN,sp|P60660|MYL6_HUMAN,tr|F8W1R7|F8W1R7_HUMAN,tr|G3V1V0|G3V1V0_HUMAN,tr|B7Z6Z4|B7Z6Z4_HUMAN,tr|G8JLA2|G8JLA2_HUMAN,tr|F8W1I5|F8W1I5_HUMAN,tr|J3KND3|J3KND3_HUMAN,tr|F8VPF3|F8VPF3_HUMAN" 9 1361.7394 1.56 46240 11916 2 1361.741828 681.877 Myosin light chain 6B OS=Homo sapiens OX=9606 GN=MYL6B PE=1 SV=1 6.05 2377.1 - 1.84E+06 - - - 1.7617 - 2.511 0.5 - 469.4 1 2 0 0.0024 13 0 0 0 1.31E+08 8.38E+07 - - - 5.0962 1 221125_WJC_METTL3_EV_vs_WT_F04.11917.11917.3 1.14E-06 17/56 R.LVVHEGSPVTSISAR.S "sp|Q9H1Z4|WDR13_HUMAN,tr|A0A087X091|A0A087X091_HUMAN" 2 1550.8417 1.47 46241 11917 3 1550.842186 517.9545 WD repeat-containing protein 13 OS=Homo sapiens OX=9606 GN=WDR13 PE=1 SV=2 6.75 2377.2 - 2.69E+06 - - - 0.3417 - 2.965 0.486 - 424.3 1 2 0 0.0005 15 0 0 0 3.93E+07 2.67E+07 - - - 6.7943 0.9967 221125_WJC_METTL3_EV_vs_WT_F04.11920.11920.2 0.094 12-Aug R.RLDFDYK.K "sp|Q99961|SH3G1_HUMAN,sp|Q99962|SH3G2_HUMAN,tr|M0R0I3|M0R0I3_HUMAN" 3 955.4763 1.27 46244 11920 2 955.474104 478.7454 Endophilin-A2 OS=Homo sapiens OX=9606 GN=SH3GL1 PE=1 SV=1 5.96 2377.4 - 1.68E+06 - - - -2.3308 - 1.577 0.234 - 375.8 1 2 0 -0.0022 7 0 0 0 2.61E+07 2.06E+07 - - - 2.212 0.9997 221125_WJC_METTL3_EV_vs_WT_F04.11921.11921.3 0.0191 Nov-40 K.AYPLADAHLTK.K "sp|P55769|NH2L1_HUMAN,tr|B1AHD1|B1AHD1_HUMAN,tr|A0A3B3IUA2|A0A3B3IUA2_HUMAN" 3 1198.6346 1.23 46245 11921 3 1198.63538 400.5522 NHP2-like protein 1 OS=Homo sapiens OX=9606 GN=SNU13 PE=1 SV=3 6.79 2377.5 - 1.24E+06 - - - 0.6316 - 1.908 0.346 - 90.2 1 2 0 0.0008 11 0 0 0 9.78E+06 7.97E+06 - - - 4.2327 0.9855 221125_WJC_METTL3_EV_vs_WT_F04.11922.11922.2 0.765 12-Jul R.R[166.11]LDFDYK[136.11].K "sp|Q99961|SH3G1_HUMAN,sp|Q99962|SH3G2_HUMAN,tr|M0R0I3|M0R0I3_HUMAN" 3 973.4988 1 46246 11922 2 973.497798 487.7567 Endophilin-A2 OS=Homo sapiens OX=9606 GN=SH3GL1 PE=1 SV=1 5.96 2377.6 - 1.23E+06 - - - -1.0303 - 1.377 0.06 - 305.1 1 2 0 -0.001 7 0 0 0 1.06E+07 1.06E+07 - - - 0.4975 0.9988 221125_WJC_METTL3_EV_vs_WT_F04.11923.11923.3 0.0108 Oct-40 K.LKPGDLVGVNK.D "sp|P17980|PRS6A_HUMAN,tr|R4GNH3|R4GNH3_HUMAN,tr|E9PMD8|E9PMD8_HUMAN,tr|E9PKD5|E9PKD5_HUMAN,tr|E9PLG2|E9PLG2_HUMAN,tr|E9PM69|E9PM69_HUMAN" 6 1138.671 1.22 46247 11923 3 1138.668609 380.5643 26S proteasome regulatory subunit 6A OS=Homo sapiens OX=9606 GN=PSMC3 PE=1 SV=3 8.59 2377.7 - 1.20E+06 - - - -2.1077 - 1.872 0.302 - 118.6 1 2 0 -0.0024 11 0 0 0 2.57E+07 2.10E+07 - - - 3.6876 0.993 221125_WJC_METTL3_EV_vs_WT_F04.11924.11924.2 0.00162 24-Dec R.SLGSVQAPSYGAR[166.11].P "sp|P05783|K1C18_HUMAN,tr|F8VZY9|F8VZY9_HUMAN" 2 1301.6603 1.57 46248 11924 2 1301.660271 651.8374 "Keratin, type I cytoskeletal 18 OS=Homo sapiens OX=9606 GN=KRT18 PE=1 SV=2" 8.46 2377.8 - 1.06E+06 - - - -0.0484 - 2.363 0.496 - 520.8 1 1 0 -0.0001 13 0 0 0 1.92E+07 1.22E+07 - - - 4.9115 0.999 221125_WJC_METTL3_EV_vs_WT_F04.11925.11925.3 0.00892 Oct-40 K.HPENYDLATLK.W "sp|P78347|GTF2I_HUMAN,sp|Q86UP8|GTD2A_HUMAN,sp|Q6EKJ0|GTD2B_HUMAN,tr|A0A494C1N8|A0A494C1N8_HUMAN,tr|A0A087WW90|A0A087WW90_HUMAN,tr|A0A0D9SF80|A0A0D9SF80_HUMAN,tr|A0A494C0I1|A0A494C0I1_HUMAN,tr|A0A494C1K3|A0A494C1K3_HUMAN" 8 1299.6459 1.52 46249 11925 3 1299.642185 434.2226 General transcription factor II-I OS=Homo sapiens OX=9606 GN=GTF2I PE=1 SV=2 5.32 2377.9 - 762482 - - - -2.8708 - 1.838 0.355 - 117.7 1 2 0 -0.0037 11 0 0 0 5.83E+06 3.85E+06 - - - 4.226 0.9996 221125_WJC_METTL3_EV_vs_WT_F04.11929.11929.3 0.00435 Oct-36 K.YEELQVTAGR.H "sp|P48668|K2C6C_HUMAN,sp|O95678|K2C75_HUMAN,sp|P02538|K2C6A_HUMAN" 3 1164.5775 11.5 46253 11929 3 1164.577977 389.1998 "Keratin, type II cytoskeletal 6C OS=Homo sapiens OX=9606 GN=KRT6C PE=1 SV=3" 4.53 2378.4 - 479424 - - - 0.4079 - 1.985 0.315 - 123.5 1 2 0 0.0005 10 0 0 0 6.00E+06 5.22E+05 - - - 4.0541 0.9888 221125_WJC_METTL3_EV_vs_WT_F04.11930.11930.3 0.00857 Aug-52 K.FLETESHPSIPPPK[136.11].L "sp|Q15643|TRIPB_HUMAN,tr|H0YJ97|H0YJ97_HUMAN" 2 1585.8232 1.39 46254 11930 3 1585.818453 529.615 Thyroid receptor-interacting protein 11 OS=Homo sapiens OX=9606 GN=TRIP11 PE=1 SV=3 5.4 2378.5 - 422541 - - - -2.9675 - 1.498 0.263 - 55.2 1 2 0 -0.0047 14 0 0 0 9.78E+06 7.05E+06 - - - 2.5449 0.9999 221125_WJC_METTL3_EV_vs_WT_F04.11932.11932.3 0.000536 15/40 R.SLGTADVHFER.K "sp|Q86V81|THOC4_HUMAN,tr|E9PB61|E9PB61_HUMAN" 2 1230.5993 0.72 46255 11932 3 1230.599218 411.207 THO complex subunit 4 OS=Homo sapiens OX=9606 GN=ALYREF PE=1 SV=3 5.3 2378.8 - 4.44E+07 - - - -0.0666 - 2.246 0.411 - 293.1 1 2 0 -0.0001 11 0 0 0 1.71E+09 2.35E+09 - - - 5.4209 0.9917 221125_WJC_METTL3_EV_vs_WT_F04.11933.11933.2 0.00993 18-Nov G.SGSGTDFTLK.L "sp|A2NJV5|KV229_HUMAN,sp|A0A087WW87|KV240_HUMAN,sp|P06310|KV230_HUMAN,sp|A0A075B6S2|KVD29_HUMAN,sp|P01614|KVD40_HUMAN,sp|P01615|KVD28_HUMAN,sp|A0A075B6S6|KVD30_HUMAN,sp|A0A075B6P5|KV228_HUMAN,sp|A0A0A0MRZ7|KVD26_HUMAN" 9 1011.4873 1163.88 46256 11933 2 1011.486096 506.7509 Immunoglobulin kappa variable 2-29 OS=Homo sapiens OX=9606 GN=IGKV2-29 PE=3 SV=2 5.55 2378.8 - 3.33E+07 - - - -1.1804 - 2.485 0.474 - 538.7 1 1 0 -0.0012 10 0 0 0 4.11E+08 3.54E+05 - - - 5.0824 0.9832 221125_WJC_METTL3_EV_vs_WT_F04.11934.11934.3 0.312 Oct-36 K.EMEQLVLDKK.Q sp|Q96A49|SYAP1_HUMAN 1 1231.6482 1.01 46257 11934 3 1231.646117 411.5567 Synapse-associated protein 1 OS=Homo sapiens OX=9606 GN=SYAP1 PE=1 SV=1 4.68 2378.8 - 4.44E+07 - - - -1.7107 - 1.46 0.187 - 122.3 1 2 0 -0.0021 10 0 0 0 5.53E+08 5.49E+08 - - - 1.7295 0.9904 221125_WJC_METTL3_EV_vs_WT_F04.11938.11938.2 0.00113 13/24 R.SLGSVQAPSYGAR.P "sp|P05783|K1C18_HUMAN,tr|F8VZY9|F8VZY9_HUMAN" 2 1291.6521 1.36 46261 11938 2 1291.650416 646.8333 "Keratin, type I cytoskeletal 18 OS=Homo sapiens OX=9606 GN=KRT18 PE=1 SV=2" 8.46 2379 - 2.65E+06 - - - -1.2759 - 2.585 0.463 - 594.6 1 1 0 -0.0016 13 0 0 0 7.05E+07 5.20E+07 - - - 4.8977 0.9998 221125_WJC_METTL3_EV_vs_WT_F04.11939.11939.2 0.000249 14/22 K.AAVELEEPEDAR.L sp|O94906|PRP6_HUMAN 1 1327.6256 2.53 46262 11939 2 1327.622772 664.8201 Pre-mRNA-processing factor 6 OS=Homo sapiens OX=9606 GN=PRPF6 PE=1 SV=1 3.91 2379.2 - 1.52E+06 - - - -2.1113 - 2.692 0.484 - 976.5 1 2 0 -0.0028 12 0 0 0 6.83E+07 2.70E+07 - - - 5.2206 1 221125_WJC_METTL3_EV_vs_WT_F04.11940.11940.2 2.52E-05 14/16 K.KLYDIDVAK.V "sp|P62750|RL23A_HUMAN,tr|K7EMA7|K7EMA7_HUMAN,tr|H7BY10|H7BY10_HUMAN,tr|K7ERT8|K7ERT8_HUMAN,tr|A8MUS3|A8MUS3_HUMAN,tr|K7EJV9|K7EJV9_HUMAN" 6 1063.5914 0.65 46263 11940 2 1063.590086 532.803 60S ribosomal protein L23a OS=Homo sapiens OX=9606 GN=RPL23A PE=1 SV=1 5.96 2379.3 - 1.02E+06 - - - -1.1988 - 2.68 0.542 - 702.5 1 2 0 -0.0013 9 0 0 0 2.90E+07 4.50E+07 - - - 5.8958 1 221125_WJC_METTL3_EV_vs_WT_F04.11941.11941.2 0.00599 20-Nov R.ADDADEFGYSR[166.11].- sp|Q7KZF4|SND1_HUMAN 1 1254.5028 0.42 46264 11941 2 1254.501611 628.2587 Staphylococcal nuclease domain-containing protein 1 OS=Homo sapiens OX=9606 GN=SND1 PE=1 SV=1 3.84 2379.4 - 943642 - - - -0.9717 - 2.609 0.597 - 590.9 1 2 0 -0.0012 11 0 0 0 5.95E+06 1.43E+07 - - - 6.0443 0.9704 221125_WJC_METTL3_EV_vs_WT_F04.11942.11942.2 8.95E-05 20-Sep F.VVFDDSEPVQK[136.11].V "sp|Q13283|G3BP1_HUMAN,tr|A0A7I2YQF2|A0A7I2YQF2_HUMAN,tr|A0A7I2V5M7|A0A7I2V5M7_HUMAN,tr|A0A7I2V5H1|A0A7I2V5H1_HUMAN,tr|A0A7I2V565|A0A7I2V565_HUMAN,tr|A0A7I2YQN9|A0A7I2YQN9_HUMAN,tr|A0A7I2YQH0|A0A7I2YQH0_HUMAN,tr|A0A7I2V494|A0A7I2V494_HUMAN" 8 1269.6332 0.97 46265 11942 2 1269.632924 635.8239 Ras GTPase-activating protein-binding protein 1 OS=Homo sapiens OX=9606 GN=G3BP1 PE=1 SV=1 4.03 2379.6 - 696604 - - - -0.2434 - 1.72 0.338 - 222.9 1 1 0 -0.0003 11 0 0 0 1.30E+07 1.34E+07 - - - 3.0045 0.9998 221125_WJC_METTL3_EV_vs_WT_F04.11943.11943.3 6.58E-05 13/44 K.ILNDDTALKEYK.L "sp|P54727|RD23B_HUMAN,tr|Q5W0S4|Q5W0S4_HUMAN,tr|Q5W0S5|Q5W0S5_HUMAN" 3 1421.7402 0.4 46266 11943 3 1421.73861 474.9207 UV excision repair protein RAD23 homolog B OS=Homo sapiens OX=9606 GN=RAD23B PE=1 SV=1 4.56 2379.7 - 681586 - - - -1.1254 - 2.37 0.473 - 225.4 1 2 1 -0.0016 12 0 0 0 4.79E+06 1.19E+07 - - - 6.2048 1 221125_WJC_METTL3_EV_vs_WT_F04.11944.11944.2 6.30E-06 15/24 Y.ILDQTNVYGSAQR[166.11].R "sp|Q9BUJ2|HNRL1_HUMAN,tr|A0A0A0MRA5|A0A0A0MRA5_HUMAN,tr|M0R3F1|M0R3F1_HUMAN,tr|B7Z4B8|B7Z4B8_HUMAN" 4 1473.7451 1.71 46267 11944 2 1473.743749 737.8798 Heterogeneous nuclear ribonucleoprotein U-like protein 1 OS=Homo sapiens OX=9606 GN=HNRNPUL1 PE=1 SV=2 5.84 2379.8 - 630124 - - - -0.9344 - 2.912 0.568 - 879.9 1 1 0 -0.0014 13 0 0 0 2.21E+07 1.29E+07 - - - 5.979 0.9996 221125_WJC_METTL3_EV_vs_WT_F04.11945.11945.3 0.000123 13/40 K.AYPLADAHLTK[136.11].K "sp|P55769|NH2L1_HUMAN,tr|B1AHD1|B1AHD1_HUMAN,tr|A0A3B3IUA2|A0A3B3IUA2_HUMAN" 3 1206.6488 1.2 46268 11945 3 1206.65075 403.2236 NHP2-like protein 1 OS=Homo sapiens OX=9606 GN=SNU13 PE=1 SV=3 6.79 2379.9 - 578587 - - - 1.597 - 1.905 0.36 - 139.5 1 2 0 0.0019 11 0 0 0 1.09E+07 9.07E+06 - - - 4.384 0.9577 221125_WJC_METTL3_EV_vs_WT_F04.11946.11946.2 0.00325 16-Oct Y.PLADAHLTK.K "sp|P55769|NH2L1_HUMAN,tr|B1AHD1|B1AHD1_HUMAN,tr|A0A3B3IUA2|A0A3B3IUA2_HUMAN" 3 964.5342 4.74 46269 11946 2 964.535208 483.2744 NHP2-like protein 1 OS=Homo sapiens OX=9606 GN=SNU13 PE=1 SV=3 7.17 2380.1 - 425235 - - - 1.0648 - 2.023 0.253 - 207.9 1 1 0 0.001 9 0 0 0 3.55E+06 7.49E+05 - - - 2.9477 1 221125_WJC_METTL3_EV_vs_WT_F04.11948.11948.3 1.13E-05 Dec-40 K.HPENYDLATLK[136.11].W "sp|P78347|GTF2I_HUMAN,sp|Q86UP8|GTD2A_HUMAN,sp|Q6EKJ0|GTD2B_HUMAN,tr|A0A494C1N8|A0A494C1N8_HUMAN,tr|A0A087WW90|A0A087WW90_HUMAN,tr|A0A0D9SF80|A0A0D9SF80_HUMAN,tr|A0A494C0I1|A0A494C0I1_HUMAN,tr|A0A494C1K3|A0A494C1K3_HUMAN" 8 1307.6601 1.65 46271 11948 3 1307.661397 436.894 General transcription factor II-I OS=Homo sapiens OX=9606 GN=GTF2I PE=1 SV=2 5.32 2380.3 - 405581 - - - 0.9796 - 2.245 0.544 - 225.8 1 2 0 0.0013 11 0 0 0 7.11E+06 4.32E+06 - - - 6.9021 0.9998 221125_WJC_METTL3_EV_vs_WT_F04.11950.11950.3 0.000249 Nov-36 K.EMEQLVLDK[136.11]K[136.11].Q sp|Q96A49|SYAP1_HUMAN 1 1247.6766 1.02 46272 11950 3 1247.674053 416.8995 Synapse-associated protein 1 OS=Homo sapiens OX=9606 GN=SYAP1 PE=1 SV=1 4.68 2380.6 - 1.59E+07 - - - -2.0606 - 1.886 0.41 - 167.5 1 2 0 -0.0026 10 0 0 0 5.59E+08 5.50E+08 - - - 4.9633 0.9999 221125_WJC_METTL3_EV_vs_WT_F04.11951.11951.2 0.00248 20-Oct K.HPENYDLATLK[136.11].W "sp|P78347|GTF2I_HUMAN,sp|Q86UP8|GTD2A_HUMAN,sp|Q6EKJ0|GTD2B_HUMAN,tr|A0A494C1N8|A0A494C1N8_HUMAN,tr|A0A087WW90|A0A087WW90_HUMAN,tr|A0A0D9SF80|A0A0D9SF80_HUMAN,tr|A0A494C0I1|A0A494C0I1_HUMAN,tr|A0A494C1K3|A0A494C1K3_HUMAN" 8 1307.6601 2.46 46273 11951 2 1307.660397 654.8373 General transcription factor II-I OS=Homo sapiens OX=9606 GN=GTF2I PE=1 SV=2 5.32 2380.7 - 494492 - - - 0.2149 - 2.401 0.477 - 251.9 1 2 0 0.0003 11 0 0 0 6.98E+07 2.84E+07 - - - 4.9335 1 221125_WJC_METTL3_EV_vs_WT_F04.11952.11952.2 6.35E-06 20-Dec K.GDVENIEVVQK[136.11].M "sp|P42704|LPPRC_HUMAN,tr|A0A804HI14|A0A804HI14_HUMAN,tr|A0A804HL40|A0A804HL40_HUMAN,tr|A0A804HKJ0|A0A804HKJ0_HUMAN,tr|A0A804HKR3|A0A804HKR3_HUMAN,tr|A0A804HIN4|A0A804HIN4_HUMAN,tr|A0A804HLG8|A0A804HLG8_HUMAN,tr|A0A804HJA1|A0A804HJA1_HUMAN,tr|A0A804HHY9|A0A804HHY9_HUMAN,tr|A0A804HI40|A0A804HI40_HUMAN,tr|A0A804HJZ1|A0A804HJZ1_HUMAN,tr|A0A804HIQ7|A0A804HIQ7_HUMAN,tr|A0A804HK30|A0A804HK30_HUMAN,tr|A0A804HKI2|A0A804HKI2_HUMAN,tr|A0A804HJI0|A0A804HJI0_HUMAN,tr|A0A804HKX6|A0A804HKX6_HUMAN,tr|A0A804HKK7|A0A804HKK7_HUMAN,tr|A0A804HIG4|A0A804HIG4_HUMAN" 18 1236.6441 1.11 46274 11952 2 1236.644158 619.3293 "Leucine-rich PPR motif-containing protein, mitochondrial OS=Homo sapiens OX=9606 GN=LRPPRC PE=1 SV=3" 4.14 2380.8 - 2.52E+06 - - - 0.021 - 2.654 0.547 - 874.6 1 2 0 0 11 0 0 0 3.88E+07 3.50E+07 - - - 5.7216 1 221125_WJC_METTL3_EV_vs_WT_F04.11953.11953.2 2.95E-09 17/24 Y.ILDQTNVYGSAQR.R "sp|Q9BUJ2|HNRL1_HUMAN,tr|A0A0A0MRA5|A0A0A0MRA5_HUMAN,tr|M0R3F1|M0R3F1_HUMAN,tr|B7Z4B8|B7Z4B8_HUMAN" 4 1463.7369 1.71 46275 11953 2 1463.736166 732.8757 Heterogeneous nuclear ribonucleoprotein U-like protein 1 OS=Homo sapiens OX=9606 GN=HNRNPUL1 PE=1 SV=2 5.84 2380.9 - 1.50E+06 - - - -0.4714 - 2.984 0.622 - 1149 1 1 0 -0.0007 13 0 0 0 2.21E+07 1.29E+07 - - - 6.4408 0.9298 221125_WJC_METTL3_EV_vs_WT_F04.11954.11954.2 2.86E-05 20-Aug F.VVFDDSEPVQK.V "sp|Q13283|G3BP1_HUMAN,tr|A0A7I2YQF2|A0A7I2YQF2_HUMAN,tr|A0A7I2V5M7|A0A7I2V5M7_HUMAN,tr|A0A7I2V5H1|A0A7I2V5H1_HUMAN,tr|A0A7I2V565|A0A7I2V565_HUMAN,tr|A0A7I2YQN9|A0A7I2YQN9_HUMAN,tr|A0A7I2YQH0|A0A7I2YQH0_HUMAN,tr|A0A7I2V494|A0A7I2V494_HUMAN" 8 1261.619 0.88 46276 11954 2 1261.622866 631.8168 Ras GTPase-activating protein-binding protein 1 OS=Homo sapiens OX=9606 GN=G3BP1 PE=1 SV=1 4.03 2381 - 1.06E+06 - - - 3.0382 - 1.709 0.437 - 170.5 1 1 0 0.0038 11 0 0 0 1.30E+07 1.47E+07 - - - 3.7172 0.9992 221125_WJC_METTL3_EV_vs_WT_F04.11955.11955.2 1.26E-05 20-Sep K.SAQEFAVDPEK.L "sp|Q2KHR3|QSER1_HUMAN,tr|A0A3B3IRW6|A0A3B3IRW6_HUMAN,tr|H0YCQ7|H0YCQ7_HUMAN" 3 1219.5721 2.26 46277 11955 2 1219.572448 610.7933 Glutamine and serine-rich protein 1 OS=Homo sapiens OX=9606 GN=QSER1 PE=1 SV=3 4.14 2381.1 - 884163 - - - 0.3001 - 1.89 0.25 - 260.4 1 2 0 0.0004 11 0 0 0 4.49E+06 1.98E+06 - - - 2.6095 0.9995 221125_WJC_METTL3_EV_vs_WT_F04.11957.11957.2 1.61E-06 28-Nov R.VPDSPSPAPSLEEGR.R sp|Q9UI36|DACH1_HUMAN 1 1536.742 3.99 46279 11957 2 1536.746167 769.3783 Dachshund homolog 1 OS=Homo sapiens OX=9606 GN=DACH1 PE=1 SV=4 4.14 2381.4 - 209061 - - - 2.7109 - 2.404 0.48 - 360.9 1 2 0 0.0042 15 0 0 0 4.86E+06 1.22E+06 - - - 4.7414 0.9998 221125_WJC_METTL3_EV_vs_WT_F04.11959.11959.2 0.000132 30-Aug R.VLESTPAESSEGLDPK[136.11].D "sp|Q8TEU7|RPGF6_HUMAN,tr|E9PCH4|E9PCH4_HUMAN,tr|A0A5F9ZHG7|A0A5F9ZHG7_HUMAN" 3 1665.8189 0.19 46281 11959 2 1665.81831 833.9167 Rap guanine nucleotide exchange factor 6 OS=Homo sapiens OX=9606 GN=RAPGEF6 PE=1 SV=2 4 2381.7 - 164677 - - - -0.3308 - 1.663 0.49 - 119.5 1 2 0 -0.0006 16 0 0 0 6.18E+05 3.21E+06 - - - 3.9104 0.9999 221125_WJC_METTL3_EV_vs_WT_F04.11961.11961.3 0.00123 Dec-48 R.TIVITSHPGQIVK[136.11].H sp|P31689|DNJA1_HUMAN 1 1399.8278 0.45 46282 11961 3 1399.826976 467.6166 DnaJ homolog subfamily A member 1 OS=Homo sapiens OX=9606 GN=DNAJA1 PE=1 SV=2 8.44 2381.9 - 7.25E+06 - - - -0.6244 - 2.298 0.421 - 109.2 1 2 0 -0.0009 13 0 0 0 1.61E+08 3.57E+08 - - - 5.4894 0.9998 221125_WJC_METTL3_EV_vs_WT_F04.11962.11962.2 2.00E-05 22-Sep R.AQPSASLGVGYR[166.11].T sp|Q96PK6|RBM14_HUMAN 1 1214.6283 1.83 46283 11962 2 1214.62747 608.3214 RNA-binding protein 14 OS=Homo sapiens OX=9606 GN=RBM14 PE=1 SV=2 8.79 2381.9 - 9.20E+06 - - - -0.6883 - 1.935 0.447 - 257.9 1 2 0 -0.0008 12 0 0 0 1.67E+08 9.12E+07 - - - 4.0791 0.9999 221125_WJC_METTL3_EV_vs_WT_F04.11963.11963.2 0.00028 18-Sep R.AEAESWYQTK.Y "sp|P48668|K2C6C_HUMAN,sp|P04259|K2C6B_HUMAN,sp|O95678|K2C75_HUMAN,sp|P02538|K2C6A_HUMAN" 4 1211.5459 1641.14 46284 11963 2 1211.545938 606.7802 "Keratin, type II cytoskeletal 6C OS=Homo sapiens OX=9606 GN=KRT6C PE=1 SV=3" 4.53 2381.9 - 2.03E+07 - - - 0.0578 - 2.11 0.479 - 268.3 1 2 0 0.0001 10 0 0 0 1.62E+09 9.86E+05 - - - 4.6631 0.9999 221125_WJC_METTL3_EV_vs_WT_F04.11964.11964.2 1.26E-06 20-Nov K.GDVENIEVVQK.M "sp|P42704|LPPRC_HUMAN,tr|A0A804HI14|A0A804HI14_HUMAN,tr|A0A804HL40|A0A804HL40_HUMAN,tr|A0A804HKJ0|A0A804HKJ0_HUMAN,tr|A0A804HKR3|A0A804HKR3_HUMAN,tr|A0A804HIN4|A0A804HIN4_HUMAN,tr|A0A804HLG8|A0A804HLG8_HUMAN,tr|A0A804HJA1|A0A804HJA1_HUMAN,tr|A0A804HHY9|A0A804HHY9_HUMAN,tr|A0A804HI40|A0A804HI40_HUMAN,tr|A0A804HJZ1|A0A804HJZ1_HUMAN,tr|A0A804HIQ7|A0A804HIQ7_HUMAN,tr|A0A804HK30|A0A804HK30_HUMAN,tr|A0A804HKI2|A0A804HKI2_HUMAN,tr|A0A804HJI0|A0A804HJI0_HUMAN,tr|A0A804HKX6|A0A804HKX6_HUMAN,tr|A0A804HKK7|A0A804HKK7_HUMAN,tr|A0A804HIG4|A0A804HIG4_HUMAN" 18 1228.6299 1.13 46285 11964 2 1228.63106 615.3222 "Leucine-rich PPR motif-containing protein, mitochondrial OS=Homo sapiens OX=9606 GN=LRPPRC PE=1 SV=3" 4.14 2382 - 2.40E+06 - - - 0.9181 - 2.424 0.528 - 715 1 2 0 0.0011 11 0 0 0 3.93E+07 3.48E+07 - - - 5.3357 0.9848 221125_WJC_METTL3_EV_vs_WT_F04.11965.11965.3 0.252 Aug-32 R.FLNLPQHER.D "sp|Q9UPW6|SATB2_HUMAN,tr|C9JR56|C9JR56_HUMAN" 2 1152.604 3.22 46286 11965 3 1152.602716 385.2086 DNA-binding protein SATB2 OS=Homo sapiens OX=9606 GN=SATB2 PE=1 SV=2 6.75 2382.1 - 1.47E+06 - - - -1.1071 - 1.463 0.17 - 68.2 1 2 0 -0.0013 9 0 0 0 1.92E+07 5.97E+06 - - - 1.5817 1 221125_WJC_METTL3_EV_vs_WT_F04.11966.11966.2 1.10E-07 15/24 K.ASLEGNLAETENR.Y "sp|Q04695|K1C17_HUMAN,tr|F5GWP8|F5GWP8_HUMAN" 2 1402.6688 3146.55 46287 11966 2 1402.667446 702.3417 "Keratin, type I cytoskeletal 17 OS=Homo sapiens OX=9606 GN=KRT17 PE=1 SV=2" 4.25 2382.2 - 1.10E+06 - - - -0.991 - 2.875 0.598 - 775.6 1 2 0 -0.0014 13 0 0 0 6.95E+08 2.21E+05 - - - 6.1678 1 221125_WJC_METTL3_EV_vs_WT_F04.11969.11969.2 9.81E-07 16/16 R.K[136.11]GVAINFVK[136.11].N "sp|P38919|IF4A3_HUMAN,tr|I3L3H2|I3L3H2_HUMAN" 2 990.6197 1.45 46290 11969 2 990.619767 496.3171 Eukaryotic initiation factor 4A-III OS=Homo sapiens OX=9606 GN=EIF4A3 PE=1 SV=4 10 2382.6 - 754664 - - - 0.0656 - 3.277 0.466 - 912.9 1 2 0 0.0001 9 0 0 0 9.22E+07 6.34E+07 - - - 5.9167 0.9815 221125_WJC_METTL3_EV_vs_WT_F04.11972.11972.3 0.248 Aug-32 R.FLNLPQHER[166.11].D "sp|Q9UPW6|SATB2_HUMAN,tr|C9JR56|C9JR56_HUMAN" 2 1162.6123 4.02 46293 11972 3 1162.609998 388.5447 DNA-binding protein SATB2 OS=Homo sapiens OX=9606 GN=SATB2 PE=1 SV=2 6.75 2383 - 490075 - - - -1.9473 - 1.56 0.189 - 53.7 3 2 0 -0.0023 9 0 0 0 1.88E+07 4.68E+06 - - - 1.7659 0.9921 221125_WJC_METTL3_EV_vs_WT_F04.11973.11973.2 0.169 20-Jun R.GSLPANVPTPR[166.11].G "sp|P33240|CSTF2_HUMAN,tr|E9PID8|E9PID8_HUMAN,tr|E7EWR4|E7EWR4_HUMAN" 3 1117.6119 2.71 46294 11973 2 1117.611394 559.8132 Cleavage stimulation factor subunit 2 OS=Homo sapiens OX=9606 GN=CSTF2 PE=1 SV=1 9.75 2383.1 - 269380 - - - -0.4769 - 1.234 0.19 - 60.9 3 2 0 -0.0005 11 0 0 0 1.01E+08 3.72E+07 - - - 0.7998 0.9999 221125_WJC_METTL3_EV_vs_WT_F04.11975.11975.2 7.66E-05 22-Dec K.AAVELEEPEDAR[166.11].L sp|O94906|PRP6_HUMAN 1 1337.6338 2.35 46295 11975 2 1337.634051 669.8242 Pre-mRNA-processing factor 6 OS=Homo sapiens OX=9606 GN=PRPF6 PE=1 SV=1 3.91 2383.3 - 1.51E+06 - - - 0.154 - 2.391 0.518 - 741.9 1 2 0 0.0002 12 0 0 0 6.87E+07 2.92E+07 - - - 5.1605 1 221125_WJC_METTL3_EV_vs_WT_F04.11977.11977.2 3.55E-08 22-Nov R.AQPSASLGVGYR.T sp|Q96PK6|RBM14_HUMAN 1 1204.62 1.5 46296 11977 2 1204.621249 603.3173 RNA-binding protein 14 OS=Homo sapiens OX=9606 GN=RBM14 PE=1 SV=2 8.79 2383.5 - 1.45E+07 - - - 1.007 - 2.194 0.632 - 410.7 1 2 0 0.0012 12 0 0 0 1.93E+08 1.29E+08 - - - 5.776 0.9751 221125_WJC_METTL3_EV_vs_WT_F04.11978.11978.2 0.0109 16-Jul S.GSGTDFTLK.L "sp|A2NJV5|KV229_HUMAN,sp|A0A087WW87|KV240_HUMAN,sp|P06310|KV230_HUMAN,sp|A0A075B6S2|KVD29_HUMAN,sp|P01614|KVD40_HUMAN,sp|P01615|KVD28_HUMAN,sp|A0A075B6S6|KVD30_HUMAN,sp|A0A075B6P5|KV228_HUMAN,sp|A0A0A0MRZ7|KVD26_HUMAN" 9 924.4553 60.09 46297 11978 2 924.455484 463.2349 Immunoglobulin kappa variable 2-29 OS=Homo sapiens OX=9606 GN=IGKV2-29 PE=3 SV=2 5.84 2383.6 - 1.11E+07 - - - 0.2401 - 1.664 0.366 - 235.7 1 1 0 0.0002 9 0 0 0 1.34E+08 2.24E+06 - - - 3.2174 0.9999 221125_WJC_METTL3_EV_vs_WT_F04.11979.11979.2 6.75E-06 13/16 R.KGVAINFVK.N "sp|P38919|IF4A3_HUMAN,tr|I3L3H2|I3L3H2_HUMAN" 2 974.5913 1.45 46298 11979 2 974.590927 488.3029 Eukaryotic initiation factor 4A-III OS=Homo sapiens OX=9606 GN=EIF4A3 PE=1 SV=4 10 2383.6 - 2.38E+06 - - - -0.3848 - 2.273 0.452 - 608.7 1 2 0 -0.0004 9 0 0 0 9.22E+07 6.34E+07 - - - 4.7548 0.9979 221125_WJC_METTL3_EV_vs_WT_F04.11980.11980.3 0.0149 Dec-48 R.AAGFER[166.11]PSPVQLK[136.11].A "sp|Q9UHI6|DDX20_HUMAN,tr|A0A7P0TBA6|A0A7P0TBA6_HUMAN,tr|A0A7P0Z4I9|A0A7P0Z4I9_HUMAN,tr|A0A7P0T8G7|A0A7P0T8G7_HUMAN,tr|A0A7P0TB94|A0A7P0TB94_HUMAN,tr|A0A7P0T9T8|A0A7P0T9T8_HUMAN,tr|A0A7P0Z4K8|A0A7P0Z4K8_HUMAN" 7 1416.7844 1.6 46299 11980 3 1416.784616 473.2687 Probable ATP-dependent RNA helicase DDX20 OS=Homo sapiens OX=9606 GN=DDX20 PE=1 SV=2 8.79 2383.7 - 1.38E+06 - - - 0.139 - 1.834 0.234 - 151.2 1 2 0 0.0002 13 0 0 0 2.51E+07 1.57E+07 - - - 2.7932 0.9997 221125_WJC_METTL3_EV_vs_WT_F04.11981.11981.2 0.00976 20-Oct R.GSLPANVPTPR.G "sp|P33240|CSTF2_HUMAN,tr|E9PID8|E9PID8_HUMAN,tr|E7EWR4|E7EWR4_HUMAN" 3 1107.6037 2.66 46300 11981 2 1107.60356 554.8091 Cleavage stimulation factor subunit 2 OS=Homo sapiens OX=9606 GN=CSTF2 PE=1 SV=1 9.75 2383.8 - 1.29E+06 - - - -0.0876 - 1.877 0.393 - 277.3 1 2 0 -0.0001 11 0 0 0 9.85E+07 3.71E+07 - - - 3.6471 0.7721 221125_WJC_METTL3_EV_vs_WT_F04.11984.11984.3 1.82 Oct-40 K.IGSVPGIHQLR.D sp|O76031|CLPX_HUMAN 1 1175.6775 1.44 46303 11984 3 1175.676577 392.8998 "ATP-dependent Clp protease ATP-binding subunit clpX-like, mitochondrial OS=Homo sapiens OX=9606 GN=CLPX PE=1 SV=2" 9.76 2384.1 - 439716 - - - -0.7774 - 1.685 0.016 - 79 4 2 0 -0.0009 11 0 0 0 5.10E+06 3.54E+06 - - - -0.0783 0.9994 221125_WJC_METTL3_EV_vs_WT_F04.11985.11985.3 0.00744 Oct-40 K.IGSVPGIHQLR[166.11].D sp|O76031|CLPX_HUMAN 1 1185.6858 9.15 46304 11985 3 1185.684964 396.2359 "ATP-dependent Clp protease ATP-binding subunit clpX-like, mitochondrial OS=Homo sapiens OX=9606 GN=CLPX PE=1 SV=2" 9.76 2384.3 - 334868 - - - -0.6722 - 2.062 0.277 - 95.5 1 2 0 -0.0008 11 0 0 0 4.35E+07 4.75E+06 - - - 3.6839 0.9962 221125_WJC_METTL3_EV_vs_WT_F04.11986.11986.2 0.00184 22-Aug R.QAYEPPPPPAYR[166.11].T sp|Q15654|TRIP6_HUMAN 1 1394.6858 4.05 46305 11986 2 1394.680893 698.3502 Thyroid receptor-interacting protein 6 OS=Homo sapiens OX=9606 GN=TRIP6 PE=1 SV=3 6 2384.4 - 270731 - - - -3.5334 - 1.461 0.387 - 195.5 1 2 0 -0.0049 12 0 0 0 1.55E+07 3.84E+06 - - - 2.8954 0.9698 221125_WJC_METTL3_EV_vs_WT_F04.11990.11990.2 3.9 14-Jul K.GITLSVRP.- tr|A0A075B6Z2|A0A075B6Z2_HUMAN 1 841.5022 999 46307 11990 2 841.501417 421.7584 T cell receptor alpha joining 56 (Fragment) OS=Homo sapiens OX=9606 GN=TRAJ56 PE=4 SV=1 9.75 2384.9 - 1.66E+07 - - - -0.8734 - 1.336 0.026 - 193.9 2 2 0 -0.0007 8 0 0 0 1.49E+08 0.00E+00 - - - -0.028 0.9998 221125_WJC_METTL3_EV_vs_WT_F04.11992.11992.3 0.00706 Sep-48 K.ASLEGNLAETENR.Y "sp|Q04695|K1C17_HUMAN,tr|F5GWP8|F5GWP8_HUMAN" 2 1402.6688 843.33 46309 11992 3 1402.668812 468.5636 "Keratin, type I cytoskeletal 17 OS=Homo sapiens OX=9606 GN=KRT17 PE=1 SV=2" 4.25 2385 - 2.48E+06 - - - -0.0171 - 1.704 0.412 - 126 1 2 0 0 13 0 0 0 9.37E+07 1.11E+05 - - - 4.5784 0.9729 221125_WJC_METTL3_EV_vs_WT_F04.11994.11994.3 0.0135 Dec-32 K.QVEELFERK.Y "sp|P78347|GTF2I_HUMAN,tr|A0A494C1K3|A0A494C1K3_HUMAN" 2 1176.6139 1.29 46311 11994 3 1176.614624 393.2119 General transcription factor II-I OS=Homo sapiens OX=9606 GN=GTF2I PE=1 SV=2 4.79 2385.2 - 997208 - - - 0.6255 - 1.938 0.061 - 205.1 1 2 0 0.0007 9 0 0 0 1.36E+07 1.05E+07 - - - 1.214 0.9993 221125_WJC_METTL3_EV_vs_WT_F04.11998.11998.2 4.71E-05 22-Oct R.GAGLGFSTAPNK[136.11].L "sp|Q1ED39|KNOP1_HUMAN,tr|H3BNU8|H3BNU8_HUMAN" 2 1126.5862 1.25 46315 11998 2 1126.589413 564.3004 Lysine-rich nucleolar protein 1 OS=Homo sapiens OX=9606 GN=KNOP1 PE=1 SV=1 8.75 2385.7 - 250842 - - - 2.8316 - 1.957 0.466 - 280 1 2 0 0.0032 12 0 0 0 1.16E+07 9.32E+06 - - - 4.2485 0.9996 221125_WJC_METTL3_EV_vs_WT_F04.11999.11999.2 0.0021 26-Aug R.ALEEEEGGTEVLSK[136.11].N "sp|Q6P1R4|DUS1L_HUMAN,tr|H0YGW8|H0YGW8_HUMAN,tr|F5H0Q0|F5H0Q0_HUMAN,tr|J3KT57|J3KT57_HUMAN" 4 1497.729 0.42 46316 11999 2 1497.727199 749.8718 tRNA-dihydrouridine(16\17) synthase [NAD(P)(+)]-like OS=Homo sapiens OX=9606 GN=DUS1L PE=1 SV=1 3.98 2385.8 - 124238 - - - -1.1918 - 1.936 0.397 - 175.3 1 2 0 -0.0018 14 0 0 0 8.87E+05 2.13E+06 - - - 3.6305 0.9983 221125_WJC_METTL3_EV_vs_WT_F04.12003.12003.2 1.06E-05 22-Dec R.FQVSVAADGAQK.E "sp|Q9H4A3|WNK1_HUMAN,tr|F5GWT4|F5GWT4_HUMAN,tr|A0A6Q8PFM0|A0A6Q8PFM0_HUMAN" 3 1219.6197 1.16 46318 12003 2 1219.62582 610.8171 Serine\threonine-protein kinase WNK1 OS=Homo sapiens OX=9606 GN=WNK1 PE=1 SV=2 5.84 2386.3 - 1.34E+06 - - - 5.0171 - 2.42 0.566 - 437.2 1 2 0 0.0061 12 0 0 0 3.96E+07 3.40E+07 - - - 5.5449 0.9998 221125_WJC_METTL3_EV_vs_WT_F04.12004.12004.3 1.18E-05 14/32 R.FANYIDK[136.11]VR[166.11].F "sp|P08670|VIME_HUMAN,tr|B0YJC4|B0YJC4_HUMAN,tr|A0A1B0GTT5|A0A1B0GTT5_HUMAN" 3 1142.6203 0.001 46319 12004 3 1142.618502 381.8807 Vimentin OS=Homo sapiens OX=9606 GN=VIM PE=1 SV=4 8.59 2386.4 - 903547 - - - -1.5858 - 2.264 0.486 - 214.9 1 2 1 -0.0018 9 0 0 0 0.00E+00 1.26E+07 - - - 6.4206 0.9999 221125_WJC_METTL3_EV_vs_WT_F04.12006.12006.3 0.000426 Dec-40 K.TQIDHYVGIAR[166.11].D sp|O95197|RTN3_HUMAN 1 1281.6705 0.83 46321 12006 3 1281.668385 428.2308 Reticulon-3 OS=Homo sapiens OX=9606 GN=RTN3 PE=1 SV=2 6.41 2386.6 - 678516 - - - -1.6541 - 2.124 0.401 - 297.5 1 2 0 -0.0021 11 0 0 0 1.30E+07 1.56E+07 - - - 5.1502 0.9997 221125_WJC_METTL3_EV_vs_WT_F04.12008.12008.2 0.00129 22-Nov R.TVTQLVAEDGSR.V "sp|Q9H4I3|TRABD_HUMAN,tr|J3KPT4|J3KPT4_HUMAN" 2 1274.6466 1.67 46323 12008 2 1274.648361 638.3306 TraB domain-containing protein OS=Homo sapiens OX=9606 GN=TRABD PE=1 SV=1 4.37 2386.9 - 371342 - - - 1.347 - 2.301 0.409 - 439 1 2 0 0.0017 12 0 0 0 6.49E+06 3.90E+06 - - - 4.254 1 221125_WJC_METTL3_EV_vs_WT_F04.12012.12012.2 9.45E-05 15/28 K.AIADTGANVVVTGGK[136.11].V "sp|P50990|TCPQ_HUMAN,tr|H7C4C8|H7C4C8_HUMAN" 2 1379.75 0.4 46325 12012 2 1379.749619 690.8823 T-complex protein 1 subunit theta OS=Homo sapiens OX=9606 GN=CCT8 PE=1 SV=4 5.88 2387.4 - 2.08E+06 - - - -0.2718 - 3.055 0.533 - 524.9 1 2 0 -0.0004 15 0 0 0 3.29E+08 8.19E+08 - - - 5.7233 0.9994 221125_WJC_METTL3_EV_vs_WT_F04.12014.12014.2 0.000321 20-Aug K.AYPLADAHLTK.K "sp|P55769|NH2L1_HUMAN,tr|B1AHD1|B1AHD1_HUMAN,tr|A0A3B3IUA2|A0A3B3IUA2_HUMAN" 3 1198.6346 26.11 46327 12014 2 1198.636403 600.3246 NHP2-like protein 1 OS=Homo sapiens OX=9606 GN=SNU13 PE=1 SV=3 6.79 2387.6 - 742255 - - - 1.485 - 1.676 0.399 - 193.8 1 2 0 0.0018 11 0 0 0 5.88E+06 2.25E+05 - - - 3.3845 0.9998 221125_WJC_METTL3_EV_vs_WT_F04.12016.12016.2 5.10E-05 20-Nov K.NQTSLLGEPPK[136.11].E sp|Q9HCJ3|RAVR2_HUMAN 1 1190.6387 1.98 46329 12016 2 1190.640414 596.3266 Ribonucleoprotein PTB-binding 2 OS=Homo sapiens OX=9606 GN=RAVER2 PE=1 SV=2 6 2387.9 - 377491 - - - 1.4799 - 2.064 0.559 - 378 1 2 0 0.0018 11 0 0 0 1.96E+07 9.89E+06 - - - 5.1296 0.9934 221125_WJC_METTL3_EV_vs_WT_F04.12018.12018.2 0.253 16-Sep K.QVEELFERK.Y "sp|P78347|GTF2I_HUMAN,tr|A0A494C1K3|A0A494C1K3_HUMAN" 2 1176.6139 1.59 46331 12018 2 1176.610083 589.3142 General transcription factor II-I OS=Homo sapiens OX=9606 GN=GTF2I PE=1 SV=2 4.79 2388.2 - 222547 - - - -3.2339 - 1.716 0.214 - 320.5 1 2 0 -0.0038 9 0 0 0 2.45E+06 1.54E+06 - - - 2.1826 0.9995 221125_WJC_METTL3_EV_vs_WT_F04.12023.12023.2 0.12 18-Oct R.EQQLAEIEAR.R "sp|Q15155|NOMO1_HUMAN,sp|Q5JPE7|NOMO2_HUMAN,sp|P69849|NOMO3_HUMAN,tr|A0A7I2V3P4|A0A7I2V3P4_HUMAN,tr|A0A7I2V6B0|A0A7I2V6B0_HUMAN,tr|A0A7I2V4D7|A0A7I2V4D7_HUMAN,tr|A0A7I2V4T6|A0A7I2V4T6_HUMAN,tr|A0A0G2JP90|A0A0G2JP90_HUMAN,tr|A0A087X117|A0A087X117_HUMAN,tr|A0A0G2JN29|A0A0G2JN29_HUMAN,tr|A0A7I2V2Z5|A0A7I2V2Z5_HUMAN,tr|A0A087WW46|A0A087WW46_HUMAN,tr|J3KN36|J3KN36_HUMAN" 13 1185.599 0.99 46335 12023 2 1185.598476 593.8068 Nodal modulator 1 OS=Homo sapiens OX=9606 GN=NOMO1 PE=1 SV=5 4.25 2388.8 - 477833 - - - -0.4133 - 2 0.268 - 465.7 1 2 0 -0.0005 10 0 0 0 3.00E+07 3.03E+07 - - - 2.9551 0.9999 221125_WJC_METTL3_EV_vs_WT_F04.12026.12026.2 8.21E-06 15/28 K.AIADTGANVVVTGGK.V "sp|P50990|TCPQ_HUMAN,tr|H7C4C8|H7C4C8_HUMAN" 2 1371.7358 0.4 46338 12026 2 1371.735639 686.8752 T-complex protein 1 subunit theta OS=Homo sapiens OX=9606 GN=CCT8 PE=1 SV=4 5.88 2389 - 2.53E+06 - - - -0.113 - 2.854 0.452 - 469.2 1 2 0 -0.0002 15 0 0 0 3.29E+08 8.19E+08 - - - 4.9578 0.9999 221125_WJC_METTL3_EV_vs_WT_F04.12027.12027.2 1.35E-05 13/22 R.FQVSVAADGAQK[136.11].E "sp|Q9H4A3|WNK1_HUMAN,tr|F5GWT4|F5GWT4_HUMAN,tr|A0A6Q8PFM0|A0A6Q8PFM0_HUMAN" 3 1227.6339 1.12 46339 12027 2 1227.634169 614.8242 Serine\threonine-protein kinase WNK1 OS=Homo sapiens OX=9606 GN=WNK1 PE=1 SV=2 5.84 2389.1 - 2.22E+06 - - - 0.2183 - 2.402 0.534 - 483.4 1 2 0 0.0003 12 0 0 0 3.86E+07 3.45E+07 - - - 5.2907 0.9998 221125_WJC_METTL3_EV_vs_WT_F04.12028.12028.2 0.00134 22-Nov R.GAGLGFSTAPNK.L "sp|Q1ED39|KNOP1_HUMAN,tr|H3BNU8|H3BNU8_HUMAN" 2 1118.572 1.21 46340 12028 2 1118.571454 560.2933 Lysine-rich nucleolar protein 1 OS=Homo sapiens OX=9606 GN=KNOP1 PE=1 SV=1 8.75 2389.2 - 1.11E+06 - - - -0.5087 - 2.011 0.493 - 271.2 1 2 0 -0.0006 12 0 0 0 1.02E+07 8.38E+06 - - - 4.5203 0.9999 221125_WJC_METTL3_EV_vs_WT_F04.12029.12029.2 1.79E-06 20-Nov K.NQTSLLGEPPK.E sp|Q9HCJ3|RAVR2_HUMAN 1 1182.6245 1.61 46341 12029 2 1182.624643 592.3195 Ribonucleoprotein PTB-binding 2 OS=Homo sapiens OX=9606 GN=RAVER2 PE=1 SV=2 6 2389.3 - 914296 - - - 0.1615 - 2.304 0.483 - 360.9 1 2 0 0.0002 11 0 0 0 2.31E+07 1.44E+07 - - - 4.8663 0.9999 221125_WJC_METTL3_EV_vs_WT_F04.12030.12030.2 0.00155 18-Oct R.VDEMSQDIVK.Y "sp|O15372|EIF3H_HUMAN,tr|B3KS98|B3KS98_HUMAN,tr|A0A087WZK9|A0A087WZK9_HUMAN,tr|E5RJT0|E5RJT0_HUMAN" 4 1162.554 2.06 46342 12030 2 1162.553722 582.2843 Eukaryotic translation initiation factor 3 subunit H OS=Homo sapiens OX=9606 GN=EIF3H PE=1 SV=1 4.03 2389.4 - 835799 - - - -0.2305 - 2.353 0.424 - 476.7 1 2 0 -0.0003 10 0 0 0 7.12E+06 3.46E+06 - - - 4.5611 0.9998 221125_WJC_METTL3_EV_vs_WT_F04.12031.12031.2 1.17E-05 16/18 R.HLANVTQLVK[136.11].Q "sp|P14373|TRI27_HUMAN,tr|A0A0G2JIZ4|A0A0G2JIZ4_HUMAN" 2 1129.6699 1.32 46343 12031 2 1129.671605 565.8422 Zinc finger protein RFP OS=Homo sapiens OX=9606 GN=TRIM27 PE=1 SV=1 8.76 2389.5 - 815916 - - - 1.5155 - 2.504 0.52 - 698.9 1 2 0 0.0017 10 0 0 0 8.79E+06 6.67E+06 - - - 5.4433 0.9999 221125_WJC_METTL3_EV_vs_WT_F04.12032.12032.2 1.91E-06 16-Oct K.DGYNYTLSK.T sp|P31949|S10AB_HUMAN 1 1059.4873 4.68 46344 12032 2 1059.486851 530.7509 Protein S100-A11 OS=Homo sapiens OX=9606 GN=S100A11 PE=1 SV=2 5.83 2389.7 - 770412 - - - -0.4144 - 1.758 0.548 - 249.3 1 2 0 -0.0004 9 0 0 0 1.58E+07 3.36E+06 - - - 4.7206 1 221125_WJC_METTL3_EV_vs_WT_F04.12034.12034.3 0.00123 15/44 R.ANVELDHATLVR[166.11].F "sp|Q9Y4P3|TBL2_HUMAN,tr|E9PF19|E9PF19_HUMAN,tr|Q96E41|Q96E41_HUMAN,tr|A0A087WXC6|A0A087WXC6_HUMAN" 4 1346.7182 1.35 46346 12034 3 1346.716654 449.9133 Transducin beta-like protein 2 OS=Homo sapiens OX=9606 GN=TBL2 PE=1 SV=1 5.32 2389.9 - 618699 - - - -1.1354 - 3.02 0.454 - 472.5 1 2 0 -0.0015 12 0 0 0 9.65E+06 7.17E+06 - - - 6.6648 0.9989 221125_WJC_METTL3_EV_vs_WT_F04.12035.12035.2 0.0125 16-Aug K.SQSAEIWEK.L sp|Q7L4I2|RSRC2_HUMAN 1 1076.5138 1.14 46347 12035 2 1076.512482 539.2642 Arginine\serine-rich coiled-coil protein 2 OS=Homo sapiens OX=9606 GN=RSRC2 PE=1 SV=1 4.53 2390.1 - 608287 - - - -1.2606 - 1.453 0.335 - 233.4 1 2 0 -0.0014 9 0 0 0 6.57E+06 5.75E+06 - - - 2.5958 0.9993 221125_WJC_METTL3_EV_vs_WT_F04.12036.12036.2 0.0502 16-Oct R.QLDNIVGER.G sp|P04259|K2C6B_HUMAN 1 1042.5407 4.93 46348 12036 2 1042.539146 522.2776 "Keratin, type II cytoskeletal 6B OS=Homo sapiens OX=9606 GN=KRT6B PE=1 SV=5" 4.37 2390.2 - 596529 - - - -1.5127 - 1.973 0.292 - 543.7 1 2 0 -0.0016 9 0 0 0 4.48E+07 9.08E+06 - - - 3.1632 0.9999 221125_WJC_METTL3_EV_vs_WT_F04.12037.12037.2 2.87E-06 13/26 R.ISDTGLAAGTVPEK[136.11].Q sp|Q7LBC6|KDM3B_HUMAN 1 1365.7231 1.56 46349 12037 2 1365.722481 683.8688 Lysine-specific demethylase 3B OS=Homo sapiens OX=9606 GN=KDM3B PE=1 SV=2 4.37 2390.3 - 595757 - - - -0.4606 - 2.513 0.544 - 420.9 1 2 0 -0.0006 14 0 0 0 1.46E+07 9.40E+06 - - - 5.3712 0.9999 221125_WJC_METTL3_EV_vs_WT_F04.12040.12040.2 1.57E-07 24-Nov R.DVLETEDEEPPPR.R "sp|Q9ULV3|CIZ1_HUMAN,tr|Q5SYW2|Q5SYW2_HUMAN,tr|F5H2X7|F5H2X7_HUMAN,tr|H0Y5D5|H0Y5D5_HUMAN,tr|A0A0U1RQR2|A0A0U1RQR2_HUMAN,tr|A0A494C0L7|A0A494C0L7_HUMAN,tr|Q9BTG3|Q9BTG3_HUMAN" 7 1524.6944 999 46352 12040 2 1524.693507 763.3545 Cip1-interacting zinc finger protein OS=Homo sapiens OX=9606 GN=CIZ1 PE=1 SV=2 3.77 2390.7 - 150231 - - - -0.5745 - 2.333 0.596 - 360.4 1 2 0 -0.0009 13 0 0 0 3.52E+06 0.00E+00 - - - 5.617 0.9998 221125_WJC_METTL3_EV_vs_WT_F04.12044.12044.2 0.000899 24-Nov K.SLNGAVPLGSNAR.E "sp|Q9H2P0|ADNP_HUMAN,tr|A0A669KBJ7|A0A669KBJ7_HUMAN" 2 1254.668 1.02 46354 12044 2 1254.668386 628.3413 Activity-dependent neuroprotector homeobox protein OS=Homo sapiens OX=9606 GN=ADNP PE=1 SV=1 9.47 2391.2 - 1.21E+06 - - - 0.2694 - 1.995 0.448 - 253.4 1 2 0 0.0003 13 0 0 0 1.62E+07 1.59E+07 - - - 4.1224 1 221125_WJC_METTL3_EV_vs_WT_F04.12045.12045.3 0.00112 14/44 R.ANVELDHATLVR.F "sp|Q9Y4P3|TBL2_HUMAN,tr|E9PF19|E9PF19_HUMAN,tr|Q96E41|Q96E41_HUMAN,tr|A0A087WXC6|A0A087WXC6_HUMAN" 4 1336.7099 1.33 46355 12045 3 1336.708422 446.5772 Transducin beta-like protein 2 OS=Homo sapiens OX=9606 GN=TBL2 PE=1 SV=1 5.32 2391.3 - 1.52E+06 - - - -1.1154 - 2.82 0.417 - 475.1 1 2 0 -0.0015 12 0 0 0 9.65E+06 7.24E+06 - - - 6.0624 0.9998 221125_WJC_METTL3_EV_vs_WT_F04.12047.12047.2 0.000223 13/24 K.SLNGAVPLGSNAR[166.11].E "sp|Q9H2P0|ADNP_HUMAN,tr|A0A669KBJ7|A0A669KBJ7_HUMAN" 2 1264.6763 1.04 46357 12047 2 1264.677114 633.3454 Activity-dependent neuroprotector homeobox protein OS=Homo sapiens OX=9606 GN=ADNP PE=1 SV=1 9.47 2391.5 - 1.20E+06 - - - 0.6294 - 2.112 0.408 - 351.4 1 2 0 0.0008 13 0 0 0 1.60E+07 1.54E+07 - - - 3.9731 0.9999 221125_WJC_METTL3_EV_vs_WT_F04.12048.12048.2 2.04E-05 13/18 R.HLANVTQLVK.Q "sp|P14373|TRI27_HUMAN,tr|A0A0G2JIZ4|A0A0G2JIZ4_HUMAN" 2 1121.6557 1.32 46358 12048 2 1121.655691 561.8351 Zinc finger protein RFP OS=Homo sapiens OX=9606 GN=TRIM27 PE=1 SV=1 8.76 2391.6 - 1.28E+06 - - - -0.0018 - 2.268 0.524 - 376.3 1 2 0 0 10 0 0 0 8.79E+06 6.67E+06 - - - 5.1971 0.9873 221125_WJC_METTL3_EV_vs_WT_F04.12049.12049.2 0.00644 16-Oct W.LNLQEYQSK[136.11].K "sp|Q96I99|SUCB2_HUMAN,tr|E9PDQ8|E9PDQ8_HUMAN" 2 1129.5859 0.86 46359 12049 2 1129.585868 565.8002 "Succinate--CoA ligase [GDP-forming] subunit beta, mitochondrial OS=Homo sapiens OX=9606 GN=SUCLG2 PE=1 SV=2" 6 2391.6 - 1.04E+06 - - - -0.0177 - 2.108 0.378 - 317.9 1 1 0 0 9 0 0 0 1.71E+07 2.00E+07 - - - 3.9904 0.9972 221125_WJC_METTL3_EV_vs_WT_F04.12050.12050.3 0.0697 Nov-56 K.AIADTGANVVVTGGK.V "sp|P50990|TCPQ_HUMAN,tr|H7C4C8|H7C4C8_HUMAN" 2 1371.7358 0.36 46360 12050 3 1371.740232 458.2525 T-complex protein 1 subunit theta OS=Homo sapiens OX=9606 GN=CCT8 PE=1 SV=4 5.88 2391.7 - 908565 - - - 3.2353 - 1.916 0.307 - 159.6 1 2 0 0.0044 15 0 0 0 1.40E+07 3.92E+07 - - - 3.6582 0.9967 221125_WJC_METTL3_EV_vs_WT_F04.12051.12051.3 0.00422 Oct-40 R.FSQMLQDKPLR.T sp|Q9H6F5|CCD86_HUMAN 1 1361.7126 0.16 46361 12051 3 1361.704854 454.9115 Coiled-coil domain-containing protein 86 OS=Homo sapiens OX=9606 GN=CCDC86 PE=1 SV=1 8.75 2391.8 - 890134 - - - -5.6561 - 1.911 0.411 - 98.7 1 2 0 -0.0077 11 0 0 0 7.01E+06 4.26E+07 - - - 4.9599 0.9996 221125_WJC_METTL3_EV_vs_WT_F04.12052.12052.2 6.64E-07 14/26 R.ISDTGLAAGTVPEK.Q sp|Q7LBC6|KDM3B_HUMAN 1 1357.7089 1.56 46362 12052 2 1357.713004 679.8617 Lysine-specific demethylase 3B OS=Homo sapiens OX=9606 GN=KDM3B PE=1 SV=2 4.37 2391.9 - 756583 - - - 3.0154 - 2.434 0.554 - 458.9 1 2 0 0.0041 14 0 0 0 1.46E+07 9.40E+06 - - - 5.3638 0.9999 221125_WJC_METTL3_EV_vs_WT_F04.12054.12054.2 6.44E-05 20-Oct K.EMQQQELAQMR.Q "sp|O00268|TAF4_HUMAN,tr|A0A0G2JRY5|A0A0G2JRY5_HUMAN,tr|V9GY03|V9GY03_HUMAN" 3 1390.6333 1.88 46364 12054 2 1390.631723 696.3239 Transcription initiation factor TFIID subunit 4 OS=Homo sapiens OX=9606 GN=TAF4 PE=1 SV=2 4.53 2392.2 - 528826 - - - -1.1477 - 2.247 0.501 - 470.2 1 2 0 -0.0016 11 0 0 0 4.92E+06 2.62E+06 - - - 4.931 0.9968 221125_WJC_METTL3_EV_vs_WT_F04.12061.12061.2 1.84 14-Jul K.SISISVAR.G sp|P04264|K2C1_HUMAN 1 831.4814 398.48 46369 12061 2 831.480188 416.748 "Keratin, type II cytoskeletal 1 OS=Homo sapiens OX=9606 GN=KRT1 PE=1 SV=6" 9.47 2393.1 - 7.38E+06 - - - -1.4781 - 1.456 0.215 - 132.2 1 2 0 -0.0012 8 0 0 0 1.14E+08 2.86E+05 - - - 1.7617 0.9995 221125_WJC_METTL3_EV_vs_WT_F04.12063.12063.2 4.72E-05 18-Oct K.DQYANYVVQK.M "sp|Q8TB72|PUM2_HUMAN,sp|Q14671|PUM1_HUMAN,tr|Q5T1Z8|Q5T1Z8_HUMAN,tr|H0YDK8|H0YDK8_HUMAN,tr|A0A0C4DG68|A0A0C4DG68_HUMAN,tr|H0YEH2|H0YEH2_HUMAN,tr|Q5T1Z4|Q5T1Z4_HUMAN,tr|E9PR38|E9PR38_HUMAN" 8 1226.5932 1.8 46371 12063 2 1226.590408 614.3039 Pumilio homolog 2 OS=Homo sapiens OX=9606 GN=PUM2 PE=1 SV=2 5.83 2393.2 - 2.77E+06 - - - -2.2371 - 1.895 0.444 - 386.8 1 2 0 -0.0027 10 0 0 0 9.76E+07 5.43E+07 - - - 4.1038 0.9997 221125_WJC_METTL3_EV_vs_WT_F04.12064.12064.2 0.00692 20-Sep R.NLSGQPNFPC[160.03]R.V sp|Q9HD45|TM9S3_HUMAN 1 1288.5983 1.83 46372 12064 2 1288.597122 645.3064 Transmembrane 9 superfamily member 3 OS=Homo sapiens OX=9606 GN=TM9SF3 PE=1 SV=2 8.25 2393.3 - 2.58E+06 - - - -0.8792 - 1.784 0.407 - 270.9 1 2 0 -0.0011 11 0 0 0 3.29E+07 1.79E+07 - - - 3.6127 0.9999 221125_WJC_METTL3_EV_vs_WT_F04.12065.12065.2 1.51E-05 13/22 R.VPSATC[160.03]QPFTPR.T sp|Q96F45|ZN503_HUMAN 1 1359.6605 1.56 46373 12065 2 1359.661922 680.8375 Zinc finger protein 503 OS=Homo sapiens OX=9606 GN=ZNF503 PE=1 SV=1 8.22 2393.3 - 1.83E+06 - - - 1.0304 - 2.63 0.466 - 601.6 1 2 0 0.0014 12 0 0 0 4.48E+08 2.86E+08 - - - 5.0267 0.9924 221125_WJC_METTL3_EV_vs_WT_F04.12066.12066.3 0.0247 Sep-40 R.VR[166.11]VELSTGMPR[166.11].R "sp|Q16629|SRSF7_HUMAN,tr|C9JAB2|C9JAB2_HUMAN,tr|A0A0B4J1Z1|A0A0B4J1Z1_HUMAN" 3 1263.6872 1.67 46374 12066 3 1263.686126 422.2364 Serine\arginine-rich splicing factor 7 OS=Homo sapiens OX=9606 GN=SRSF7 PE=1 SV=1 9.57 2393.4 - 1.03E+06 - - - -0.8744 - 1.865 0.237 - 116.5 1 2 1 -0.0011 11 0 0 0 2.58E+07 1.54E+07 - - - 2.9526 0.993 221125_WJC_METTL3_EV_vs_WT_F04.12071.12071.3 0.107 Sep-32 K.VEFFPHQEK.D "sp|Q5T8P6|RBM26_HUMAN,tr|A0A087X0H9|A0A087X0H9_HUMAN" 2 1159.5662 0.95 46379 12071 3 1159.563973 387.5293 RNA-binding protein 26 OS=Homo sapiens OX=9606 GN=RBM26 PE=1 SV=3 5.4 2394 - 496309 - - - -1.9283 - 1.672 0.204 - 96.5 1 2 0 -0.0022 9 0 0 0 1.10E+07 1.16E+07 - - - 2.3629 1 221125_WJC_METTL3_EV_vs_WT_F04.12081.12081.2 8.29E-08 18-Dec K.DQYANYVVQK[136.11].M "sp|Q8TB72|PUM2_HUMAN,sp|Q14671|PUM1_HUMAN,tr|Q5T1Z8|Q5T1Z8_HUMAN,tr|H0YDK8|H0YDK8_HUMAN,tr|A0A0C4DG68|A0A0C4DG68_HUMAN,tr|H0YEH2|H0YEH2_HUMAN,tr|Q5T1Z4|Q5T1Z4_HUMAN,tr|E9PR38|E9PR38_HUMAN" 8 1234.6074 1.8 46387 12081 2 1234.606775 618.311 Pumilio homolog 2 OS=Homo sapiens OX=9606 GN=PUM2 PE=1 SV=2 5.83 2395.4 - 4.63E+06 - - - -0.4674 - 2.307 0.608 - 522.2 1 2 0 -0.0006 10 0 0 0 9.76E+07 5.43E+07 - - - 5.8649 0.9997 221125_WJC_METTL3_EV_vs_WT_F04.12083.12083.3 0.00425 Aug-44 M.PAYFQRPENALK.R sp|Q14152|EIF3A_HUMAN 1 1432.7463 1.33 46389 12083 3 1432.74599 478.5894 Eukaryotic translation initiation factor 3 subunit A OS=Homo sapiens OX=9606 GN=EIF3A PE=1 SV=1 9 2395.5 - 2.32E+06 - - - -0.2157 - 1.692 0.377 - 62.5 1 2 0 -0.0003 12 0 0 0 2.88E+07 2.16E+07 - - - 4.2008 0.9999 221125_WJC_METTL3_EV_vs_WT_F04.12085.12085.2 1.40E-07 13/20 R.NLSGQPNFPC[160.03]R[166.11].V sp|Q9HD45|TM9S3_HUMAN 1 1298.6065 2.32 46391 12085 2 1298.607028 650.3105 Transmembrane 9 superfamily member 3 OS=Homo sapiens OX=9606 GN=TM9SF3 PE=1 SV=2 8.25 2395.6 - 1.92E+06 - - - 0.3873 - 2.438 0.486 - 607.1 1 2 0 0.0005 11 0 0 0 3.88E+07 1.67E+07 - - - 5.0413 0.9998 221125_WJC_METTL3_EV_vs_WT_F04.12086.12086.3 0.000531 Dec-44 M.PAYFQR[166.11]PENALK[136.11].R sp|Q14152|EIF3A_HUMAN 1 1450.7688 1.35 46392 12086 3 1450.767807 484.5969 Eukaryotic translation initiation factor 3 subunit A OS=Homo sapiens OX=9606 GN=EIF3A PE=1 SV=1 9 2395.6 - 1.87E+06 - - - -0.6631 - 2.252 0.324 - 201.6 1 2 0 -0.001 12 0 0 0 2.92E+07 2.16E+07 - - - 4.4023 0.9999 221125_WJC_METTL3_EV_vs_WT_F04.12090.12090.2 2.82E-05 20-Nov K.QAEESMVASMR[166.11].L "sp|Q8N6H7|ARFG2_HUMAN,tr|E9PIY6|E9PIY6_HUMAN,tr|E9PQP3|E9PQP3_HUMAN,tr|G5E9L0|G5E9L0_HUMAN,tr|A0A0D9SF70|A0A0D9SF70_HUMAN" 5 1247.5514 4.37 46396 12090 2 1247.550096 624.783 ADP-ribosylation factor GTPase-activating protein 2 OS=Homo sapiens OX=9606 GN=ARFGAP2 PE=1 SV=1 4.53 2396.1 - 696680 - - - -1.0268 - 2.242 0.496 - 517.6 1 2 0 -0.0013 11 0 0 0 3.06E+07 7.00E+06 - - - 4.8882 0.9972 221125_WJC_METTL3_EV_vs_WT_F04.12095.12095.3 0.0403 Sep-52 K.FLETESHPSIPPPK.L "sp|Q15643|TRIPB_HUMAN,tr|H0YJ97|H0YJ97_HUMAN" 2 1577.809 1.36 46401 12095 3 1577.807261 526.9436 Thyroid receptor-interacting protein 11 OS=Homo sapiens OX=9606 GN=TRIP11 PE=1 SV=3 5.4 2396.7 - 362257 - - - -1.0762 - 1.347 0.295 - 60.6 1 2 0 -0.0017 14 0 0 0 1.29E+07 9.48E+06 - - - 2.6201 0.9938 221125_WJC_METTL3_EV_vs_WT_F04.12098.12098.2 3.34E-06 14/24 Y.TISQATAAGDVIK[136.11].A "sp|P22695|QCR2_HUMAN,tr|H3BRG4|H3BRG4_HUMAN" 2 1281.702 1.8 46404 12098 2 1281.702429 641.8583 "Cytochrome b-c1 complex subunit 2, mitochondrial OS=Homo sapiens OX=9606 GN=UQCRC2 PE=1 SV=3" 5.5 2397.1 - 240789 - - - 0.3495 - 2.512 0.52 - 436.7 1 1 0 0.0004 13 0 0 0 5.63E+06 3.13E+06 - - - 5.2456 0.9762 221125_WJC_METTL3_EV_vs_WT_F04.12101.12101.2 0.0395 16-Aug R.QAELAQWQK[136.11].V "sp|Q9Y2R0|COA3_HUMAN,tr|K7EPV0|K7EPV0_HUMAN" 2 1108.5757 1.64 46405 12101 2 1108.569999 555.2951 "Cytochrome c oxidase assembly factor 3 homolog, mitochondrial OS=Homo sapiens OX=9606 GN=COA3 PE=1 SV=1" 6 2397.5 - 8.87E+06 - - - -5.1047 - 1.571 0.255 - 185.3 1 2 0 -0.0057 9 0 0 0 1.76E+08 1.07E+08 - - - 2.2295 0.9349 221125_WJC_METTL3_EV_vs_WT_F04.12103.12103.2 0.0463 12-Jul L.GLQFHSR[166.11].L sp|O43615|TIM44_HUMAN 1 853.4434 1.11 46407 12103 2 853.442978 427.729 Mitochondrial import inner membrane translocase subunit TIM44 OS=Homo sapiens OX=9606 GN=TIMM44 PE=1 SV=2 9.76 2397.6 - 1.86E+06 - - - -0.5003 - 1.581 0.24 - 188.5 1 1 0 -0.0004 7 0 0 0 2.25E+07 2.03E+07 - - - 2.2649 0.8773 221125_WJC_METTL3_EV_vs_WT_F04.12104.12104.2 0.793 22-Apr K.C[160.03]LDPVDTPNPTR.R sp|P03973|SLPI_HUMAN 1 1383.6453 117.1 46408 12104 2 1383.64532 692.8299 Antileukoproteinase OS=Homo sapiens OX=9606 GN=SLPI PE=1 SV=2 4.21 2397.7 - 2.36E+07 - - - 0.0405 - 0.896 0.114 - 21.4 26 2 0 0.0001 12 0 0 0 1.50E+07 1.28E+05 - - - -1.038 0.9997 221125_WJC_METTL3_EV_vs_WT_F04.12105.12105.2 0.000131 18-Nov R.VFELNSDSGK.S sp|Q9NW68|BSDC1_HUMAN 1 1094.5244 3.53 46409 12105 2 1094.524459 548.2695 BSD domain-containing protein 1 OS=Homo sapiens OX=9606 GN=BSDC1 PE=1 SV=1 4.37 2397.8 - 1.48E+06 - - - 0.0503 - 2.082 0.332 - 431.2 1 2 0 0.0001 10 0 0 0 2.08E+07 5.89E+06 - - - 3.5401 1 221125_WJC_METTL3_EV_vs_WT_F04.12107.12107.3 2.12E-05 13/48 R.SLQEEHVAVAQLR.E sp|Q15149|PLEC_HUMAN 1 1478.7841 1.89 46411 12107 3 1478.783353 493.9353 Plectin OS=Homo sapiens OX=9606 GN=PLEC PE=1 SV=3 5.38 2398 - 1.01E+06 - - - -0.5329 - 2.02 0.508 - 175.7 1 2 0 -0.0008 13 0 0 0 7.28E+06 3.85E+06 - - - 6.1098 0.9997 221125_WJC_METTL3_EV_vs_WT_F04.12109.12109.3 0.000664 Dec-48 R.SLQEEHVAVAQLR[166.11].E sp|Q15149|PLEC_HUMAN 1 1488.7924 1.92 46413 12109 3 1488.792723 497.2714 Plectin OS=Homo sapiens OX=9606 GN=PLEC PE=1 SV=3 5.38 2398.2 - 617911 - - - 0.2096 - 1.72 0.376 - 118.6 1 2 0 0.0003 13 0 0 0 7.28E+06 3.80E+06 - - - 4.2023 0.9996 221125_WJC_METTL3_EV_vs_WT_F04.12110.12110.2 2.32E-05 13/24 K.IVEQPTVSVTEPK[136.11].L sp|Q15054|DPOD3_HUMAN 1 1433.7857 0.58 46414 12110 2 1433.789502 717.9001 DNA polymerase delta subunit 3 OS=Homo sapiens OX=9606 GN=POLD3 PE=1 SV=2 4.53 2398.4 - 550007 - - - 2.644 - 2.199 0.533 - 515.4 1 2 0 0.0038 13 0 0 0 6.68E+06 1.15E+07 - - - 4.999 0.9998 221125_WJC_METTL3_EV_vs_WT_F04.12111.12111.2 7.41E-06 24-Nov K.YYTPVPC[160.03]ESATAK[136.11].A sp|P51692|STA5B_HUMAN 1 1493.6952 0.09 46415 12111 2 1493.69655 747.8549 Signal transducer and activator of transcription 5B OS=Homo sapiens OX=9606 GN=STAT5B PE=1 SV=2 5.99 2398.5 - 432645 - - - 0.9165 - 1.718 0.517 - 313.7 1 2 0 0.0014 13 0 0 0 8.26E+05 9.30E+06 - - - 4.248 1 221125_WJC_METTL3_EV_vs_WT_F04.12112.12112.2 2.89E-10 14/28 R.GGGAFVQNSQPVAVR.G sp|P33176|KINH_HUMAN 1 1485.7688 1.14 46416 12112 2 1485.767178 743.8917 Kinesin-1 heavy chain OS=Homo sapiens OX=9606 GN=KIF5B PE=1 SV=1 9.75 2398.6 - 337391 - - - -1.1085 - 2.818 0.658 - 508.1 1 2 0 -0.0016 15 0 0 0 4.06E+06 3.56E+06 - - - 6.4476 0.9889 221125_WJC_METTL3_EV_vs_WT_F04.12113.12113.2 0.00124 18-Oct R.MAQEVLTHLK[136.11].E "sp|O14980|XPO1_HUMAN,tr|F8WF71|F8WF71_HUMAN,tr|A0A7I2V461|A0A7I2V461_HUMAN,tr|A0A7P0Z4B7|A0A7P0Z4B7_HUMAN,tr|A0A7I2V2H0|A0A7I2V2H0_HUMAN,tr|A0A7I2YQP1|A0A7I2YQP1_HUMAN,tr|A0A7I2V3N0|A0A7I2V3N0_HUMAN,tr|A0A7I2V4A3|A0A7I2V4A3_HUMAN,tr|C9J673|C9J673_HUMAN,tr|C9JKM9|C9JKM9_HUMAN,tr|C9IYM2|C9IYM2_HUMAN,tr|A0A7I2YQV4|A0A7I2YQV4_HUMAN,tr|A0A7I2YQX3|A0A7I2YQX3_HUMAN,tr|A0A7I2V2Y6|A0A7I2V2Y6_HUMAN,tr|A0A7I2V2C5|A0A7I2V2C5_HUMAN,tr|A0A7I2V3J1|A0A7I2V3J1_HUMAN,tr|A0A7I2V3P3|A0A7I2V3P3_HUMAN,tr|A0A7I2V2S3|A0A7I2V2S3_HUMAN" 18 1176.6416 0.28 46417 12113 2 1176.648357 589.3281 Exportin-1 OS=Homo sapiens OX=9606 GN=XPO1 PE=1 SV=1 6.5 2398.8 - 330336 - - - 5.718 - 1.982 0.334 - 410.1 1 2 0 0.0067 10 0 0 0 5.63E+05 2.00E+06 - - - 3.4154 0.9995 221125_WJC_METTL3_EV_vs_WT_F04.12114.12114.3 0.00828 Sep-36 K.LHLSSPDNFR.Y "sp|Q9UM54|MYO6_HUMAN,tr|A0A590UK86|A0A590UK86_HUMAN,tr|A0A590UK71|A0A590UK71_HUMAN,tr|A0A0D9SGC1|A0A0D9SGC1_HUMAN,tr|A0A0A0MRM8|A0A0A0MRM8_HUMAN,tr|A0A5F9ZI03|A0A5F9ZI03_HUMAN,tr|A0A590UK22|A0A590UK22_HUMAN,tr|A0A590UJY4|A0A590UJY4_HUMAN,tr|A0A590UJ40|A0A590UJ40_HUMAN,tr|A0A590UJ75|A0A590UJ75_HUMAN,tr|E7EW20|E7EW20_HUMAN,tr|A0A590UKB0|A0A590UKB0_HUMAN,tr|A0A1Y0BRN3|A0A1Y0BRN3_HUMAN" 13 1184.5938 0.17 46418 12114 3 1184.592276 395.8719 Unconventional myosin-VI OS=Homo sapiens OX=9606 GN=MYO6 PE=1 SV=4 6.74 2398.9 - 239099 - - - -1.3042 - 1.639 0.351 - 113.6 1 2 0 -0.0015 10 0 0 0 4.16E+06 2.42E+07 - - - 3.8958 0.9998 221125_WJC_METTL3_EV_vs_WT_F04.12120.12120.2 0.000436 16-Dec R.QAELAQWQK.V "sp|Q9Y2R0|COA3_HUMAN,tr|K7EPV0|K7EPV0_HUMAN" 2 1100.5615 1.65 46422 12120 2 1100.562141 551.288 "Cytochrome c oxidase assembly factor 3 homolog, mitochondrial OS=Homo sapiens OX=9606 GN=COA3 PE=1 SV=1" 6 2399.7 - 1.84E+07 - - - 0.6206 - 2.245 0.427 - 790 1 2 0 0.0007 9 0 0 0 1.77E+08 1.07E+08 - - - 4.5342 0.9998 221125_WJC_METTL3_EV_vs_WT_F04.12121.12121.2 0.00265 16-Sep R.SLVNLGGSK.S sp|P04264|K2C1_HUMAN 1 873.492 6773.23 46423 12121 2 873.491667 437.7533 "Keratin, type II cytoskeletal 1 OS=Homo sapiens OX=9606 GN=KRT1 PE=1 SV=6" 8.47 2399.8 - 3.34E+06 - - - -0.3606 - 1.726 0.498 - 242.1 1 2 0 -0.0003 9 0 0 0 4.97E+08 7.34E+04 - - - 4.2982 0.9999 221125_WJC_METTL3_EV_vs_WT_F04.12122.12122.2 4.07E-07 14/22 R.VPSATC[160.03]QPFTPR[166.11].T sp|Q96F45|ZN503_HUMAN 1 1369.6688 1.56 46424 12122 2 1369.669346 685.8417 Zinc finger protein 503 OS=Homo sapiens OX=9606 GN=ZNF503 PE=1 SV=1 8.22 2399.8 - 1.15E+07 - - - 0.4052 - 2.807 0.501 - 847 1 2 0 0.0006 12 0 0 0 4.48E+08 2.86E+08 - - - 5.4569 0.9998 221125_WJC_METTL3_EV_vs_WT_F04.12125.12125.2 0.000128 20-Dec K.ESAEFQTQLEK.K sp|P12270|TPR_HUMAN 1 1308.6198 0.84 46427 12125 2 1308.621682 655.3172 Nucleoprotein TPR OS=Homo sapiens OX=9606 GN=TPR PE=1 SV=3 4.25 2400.1 - 807255 - - - 1.468 - 2.439 0.477 - 744.1 1 2 0 0.0019 11 0 0 0 6.70E+06 7.98E+06 - - - 4.9755 0.9996 221125_WJC_METTL3_EV_vs_WT_F04.12128.12128.3 0.00444 Sep-36 K.VAK[136.11]PNFVVMK[136.11].L sp|Q5VZE5|NAA35_HUMAN 1 1147.6758 0.001 46430 12128 3 1147.67638 383.5659 "N-alpha-acetyltransferase 35, NatC auxiliary subunit OS=Homo sapiens OX=9606 GN=NAA35 PE=1 SV=1" 10 2400.5 - 433644 - - - 0.474 - 1.952 0.315 - 69.6 1 2 0 0.0005 10 0 0 0 0.00E+00 3.55E+06 - - - 4.0051 0.9995 221125_WJC_METTL3_EV_vs_WT_F04.12129.12129.3 0.00791 Nov-52 R.IVNHPTMLQDPDVR.E "sp|Q13596|SNX1_HUMAN,tr|H0YK42|H0YK42_HUMAN" 2 1633.8246 2.13 46431 12129 3 1633.827094 545.6155 Sorting nexin-1 OS=Homo sapiens OX=9606 GN=SNX1 PE=1 SV=3 5.21 2400.6 - 432668 - - - 1.5106 - 1.776 0.356 - 90.6 1 2 0 0.0025 14 0 0 0 4.90E+06 2.30E+06 - - - 4.0348 0.9998 221125_WJC_METTL3_EV_vs_WT_F04.12130.12130.2 5.22E-05 24-Oct K.IVEQPTVSVTEPK.L sp|Q15054|DPOD3_HUMAN 1 1425.7715 0.58 46432 12130 2 1425.772463 713.893 DNA polymerase delta subunit 3 OS=Homo sapiens OX=9606 GN=POLD3 PE=1 SV=2 4.53 2400.7 - 399738 - - - 0.6677 - 2.025 0.455 - 264.3 1 2 0 0.001 13 0 0 0 6.68E+06 1.15E+07 - - - 4.2122 0.9996 221125_WJC_METTL3_EV_vs_WT_F04.12131.12131.2 0.00553 18-Nov K.IGAVEEELNR[166.11].V "sp|P52732|KIF11_HUMAN,tr|A0A7I2YQY4|A0A7I2YQY4_HUMAN,tr|A0A7I2V3A9|A0A7I2V3A9_HUMAN,tr|A0A7I2V3V3|A0A7I2V3V3_HUMAN" 4 1138.5858 4.36 46433 12131 2 1138.582985 570.3002 Kinesin-like protein KIF11 OS=Homo sapiens OX=9606 GN=KIF11 PE=1 SV=2 4.25 2400.9 - 394149 - - - -2.4478 - 2.267 0.433 - 514 1 2 0 -0.0028 10 0 0 0 1.93E+07 4.42E+06 - - - 4.5228 0.9854 221125_WJC_METTL3_EV_vs_WT_F04.12132.12132.2 0.000695 18-Sep L.GGHGPSFPLK[136.11].G sp|P13010|XRCC5_HUMAN 1 1003.5331 1.01 46434 12132 2 1003.53252 502.7738 X-ray repair cross-complementing protein 5 OS=Homo sapiens OX=9606 GN=XRCC5 PE=1 SV=3 8.76 2401 - 283929 - - - -0.5431 - 1.834 0.423 - 264.6 1 1 0 -0.0005 10 0 0 0 6.29E+06 6.21E+06 - - - 3.858 1 221125_WJC_METTL3_EV_vs_WT_F04.12134.12134.2 3.70E-06 22-Dec K.LYVYNTDTDNC[160.03]R[166.11].E sp|Q9H8Y8|GORS2_HUMAN 1 1542.6648 0.98 46436 12134 2 1542.664786 772.3397 Golgi reassembly-stacking protein 2 OS=Homo sapiens OX=9606 GN=GORASP2 PE=1 SV=3 4.21 2401.2 - 265589 - - - -0.0266 - 2.322 0.668 - 528.7 1 2 0 0 12 0 0 0 4.82E+06 4.92E+06 - - - 6.1914 0.9999 221125_WJC_METTL3_EV_vs_WT_F04.12137.12137.2 1.07E-07 28-Dec R.LLSGPSQESPQTLGK[136.11].E "sp|Q9BWE0|REPI1_HUMAN,tr|C9JZE3|C9JZE3_HUMAN,tr|E7EVL6|E7EVL6_HUMAN,tr|C9JYJ8|C9JYJ8_HUMAN" 4 1548.8239 1.1 46439 12137 2 1548.822478 775.4192 Replication initiator 1 OS=Homo sapiens OX=9606 GN=REPIN1 PE=1 SV=1 6 2401.6 - 121614 - - - -0.9097 - 2.641 0.537 - 475.6 1 2 0 -0.0014 15 0 0 0 1.42E+07 1.29E+07 - - - 5.3945 1 221125_WJC_METTL3_EV_vs_WT_F04.12140.12140.3 3.51E-06 15/44 R.VAYVSFGPHAGK[136.11].L "sp|P50914|RL14_HUMAN,tr|E7EPB3|E7EPB3_HUMAN" 2 1239.6492 1.33 46440 12140 3 1239.649101 414.2237 60S ribosomal protein L14 OS=Homo sapiens OX=9606 GN=RPL14 PE=1 SV=4 8.57 2402 - 4.58E+06 - - - -0.0452 - 2.716 0.502 - 233.1 1 2 0 -0.0001 12 0 0 0 1.22E+08 9.17E+07 - - - 6.9063 0.9982 221125_WJC_METTL3_EV_vs_WT_F04.12141.12141.2 0.000229 22-Nov R.ELISNSSDALDK[136.11].L "sp|P07900|HS90A_HUMAN,sp|Q14568|HS902_HUMAN,tr|G3V2J8|G3V2J8_HUMAN" 3 1298.6445 0.57 46441 12141 2 1298.650464 650.3295 Heat shock protein HSP 90-alpha OS=Homo sapiens OX=9606 GN=HSP90AA1 PE=1 SV=5 4.03 2402.1 - 4.01E+06 - - - 4.5725 - 2.275 0.494 - 370.9 1 2 0 0.0059 12 0 0 0 8.83E+07 1.54E+08 - - - 4.8506 0.9998 221125_WJC_METTL3_EV_vs_WT_F04.12142.12142.2 0.000831 22-Sep R.ALEESNYELEGK.L "sp|P13645|K1C10_HUMAN,tr|A0A1B0GVI3|A0A1B0GVI3_HUMAN" 2 1380.6409 1547.44 46442 12142 2 1380.641825 691.3277 "Keratin, type I cytoskeletal 10 OS=Homo sapiens OX=9606 GN=KRT10 PE=1 SV=6" 4.09 2402.1 - 8.18E+06 - - - 0.6772 - 1.977 0.426 - 169.2 1 2 0 0.0009 12 0 0 0 1.39E+10 9.00E+06 - - - 3.9805 0.9843 221125_WJC_METTL3_EV_vs_WT_F04.12143.12143.3 0.354 Dec-44 K.LK[136.11]QSLPPGLAVK[136.11].E sp|P63173|RL38_HUMAN 1 1265.8042 1.07 46443 12143 3 1265.804383 422.942 60S ribosomal protein L38 OS=Homo sapiens OX=9606 GN=RPL38 PE=1 SV=2 10 2402.2 - 3.24E+06 - - - 0.1383 - 1.76 0.212 - 179.4 1 2 1 0.0002 12 0 0 0 4.45E+08 4.16E+08 - - - 2.4705 0.8212 221125_WJC_METTL3_EV_vs_WT_F04.12147.12147.2 3.59E-07 16-Nov Y.PLADAHLTK[136.11].K "sp|P55769|NH2L1_HUMAN,tr|B1AHD1|B1AHD1_HUMAN,tr|A0A3B3IUA2|A0A3B3IUA2_HUMAN" 3 972.5484 2.16 46447 12147 2 972.553541 487.2815 NHP2-like protein 1 OS=Homo sapiens OX=9606 GN=SNU13 PE=1 SV=3 7.17 2402.5 - 626993 - - - 5.3056 - 2.052 0.461 - 269 1 1 0 0.0052 9 0 0 0 3.06E+07 1.42E+07 - - - 4.5239 0.9966 221125_WJC_METTL3_EV_vs_WT_F04.12151.12151.3 0.016 Jul-48 R.YMGDLSGGQVLKK.V "sp|P30519|HMOX2_HUMAN,tr|I3L159|I3L159_HUMAN,tr|A0A087WT44|A0A087WT44_HUMAN,tr|I3L1F5|I3L1F5_HUMAN" 4 1394.7228 1.29 46451 12151 3 1394.722686 465.9149 Heme oxygenase 2 OS=Homo sapiens OX=9606 GN=HMOX2 PE=1 SV=2 8.5 2403 - 316448 - - - -0.0717 - 1.436 0.278 - 37.5 2 2 0 -0.0001 13 0 0 0 2.82E+06 2.19E+06 - - - 2.4812 0.9999 221125_WJC_METTL3_EV_vs_WT_F04.12152.12152.2 0.000948 14/24 K.ATDAEADVASLNR.R "sp|P09493|TPM1_HUMAN,sp|P07951|TPM2_HUMAN,tr|A0A0S2Z4G6|A0A0S2Z4G6_HUMAN,tr|A7XZE4|A7XZE4_HUMAN,tr|H0YKX5|H0YKX5_HUMAN,tr|Q6ZN40|Q6ZN40_HUMAN,tr|H0YKP3|H0YKP3_HUMAN,tr|Q5TCU3|Q5TCU3_HUMAN" 8 1331.6317 2.23 46452 12152 2 1331.630453 666.8231 Tropomyosin alpha-1 chain OS=Homo sapiens OX=9606 GN=TPM1 PE=1 SV=2 4.03 2403.1 - 222874 - - - -0.9537 - 2.81 0.498 - 976.3 1 2 0 -0.0013 13 0 0 0 6.10E+06 2.74E+06 - - - 5.3705 0.9998 221125_WJC_METTL3_EV_vs_WT_F04.12156.12156.3 0.00414 Oct-44 R.VPSATC[160.03]QPFTPR[166.11].T sp|Q96F45|ZN503_HUMAN 1 1369.6688 1.66 46454 12156 3 1369.669106 457.5635 Zinc finger protein 503 OS=Homo sapiens OX=9606 GN=ZNF503 PE=1 SV=1 8.22 2403.7 - 968650 - - - 0.23 - 2.147 0.346 - 158.1 1 2 0 0.0003 12 0 0 0 2.94E+07 1.77E+07 - - - 4.5154 0.9988 221125_WJC_METTL3_EV_vs_WT_F04.12157.12157.2 0.00198 14/22 K.LK[136.11]QSLPPGLAVK[136.11].E sp|P63173|RL38_HUMAN 1 1265.8042 1.11 46455 12157 2 1265.804921 633.9094 60S ribosomal protein L38 OS=Homo sapiens OX=9606 GN=RPL38 PE=1 SV=2 10 2403.8 - 875238 - - - 0.5633 - 2.566 0.508 - 453.3 1 2 1 0.0007 12 0 0 0 6.67E+07 6.02E+07 - - - 5.2723 0.9981 221125_WJC_METTL3_EV_vs_WT_F04.12158.12158.2 0.034 13/22 K.LKQSLPPGLAVK.E sp|P63173|RL38_HUMAN 1 1249.7758 1.11 46456 12158 2 1249.776883 625.8952 60S ribosomal protein L38 OS=Homo sapiens OX=9606 GN=RPL38 PE=1 SV=2 10 2403.9 - 767821 - - - 0.8602 - 2.501 0.433 - 439.5 1 2 1 0.0011 12 0 0 0 6.67E+07 6.02E+07 - - - 4.6508 0.9997 221125_WJC_METTL3_EV_vs_WT_F04.12159.12159.2 0.0172 14-Aug R.FDLQNPSR.M sp|Q92922|SMRC1_HUMAN 1 975.4774 2.82 46457 12159 2 975.477581 488.746 SWI\SNF complex subunit SMARCC1 OS=Homo sapiens OX=9606 GN=SMARCC1 PE=1 SV=3 5.84 2404.1 - 600392 - - - 0.1917 - 1.589 0.42 - 259.1 1 2 0 0.0002 8 0 0 0 3.82E+07 1.36E+07 - - - 3.5398 1 221125_WJC_METTL3_EV_vs_WT_F04.12162.12162.3 1.20E-05 17/40 R.FPGQLNADLRK.L "sp|P04350|TBB4A_HUMAN,sp|Q9BVA1|TBB2B_HUMAN,sp|A6NNZ2|TBB8B_HUMAN,sp|P07437|TBB5_HUMAN,sp|Q13509|TBB3_HUMAN,sp|Q13885|TBB2A_HUMAN,sp|P68371|TBB4B_HUMAN,sp|Q9BUF5|TBB6_HUMAN,sp|Q3ZCM7|TBB8_HUMAN,sp|Q9H4B7|TBB1_HUMAN,tr|M0R2D3|M0R2D3_HUMAN,tr|A0A0B4J269|A0A0B4J269_HUMAN,tr|Q5ST81|Q5ST81_HUMAN,tr|Q5JP53|Q5JP53_HUMAN,tr|K7ESM5|K7ESM5_HUMAN,tr|A0A075B736|A0A075B736_HUMAN,tr|G3V2A3|G3V2A3_HUMAN,tr|Q5SQY0|Q5SQY0_HUMAN" 18 1257.683 0.79 46460 12162 3 1257.684267 420.2349 Tubulin beta-4A chain OS=Homo sapiens OX=9606 GN=TUBB4A PE=1 SV=2 8.75 2404.4 - 443306 - - - 1.0313 - 2.663 0.452 - 300.6 1 2 0 0.0013 11 0 0 0 5.21E+07 6.61E+07 - - - 6.3615 0.9998 221125_WJC_METTL3_EV_vs_WT_F04.12164.12164.2 0.00182 18-Oct K.GNIIISTPEK[136.11].W sp|O75643|U520_HUMAN 1 1078.6114 2.24 46462 12164 2 1078.61124 540.313 U5 small nuclear ribonucleoprotein 200 kDa helicase OS=Homo sapiens OX=9606 GN=SNRNP200 PE=1 SV=2 6 2404.7 - 435813 - - - -0.1252 - 1.96 0.409 - 330.8 1 2 0 -0.0001 10 0 0 0 1.19E+07 5.31E+06 - - - 3.9402 0.983 221125_WJC_METTL3_EV_vs_WT_F04.12165.12165.2 4.67E-06 18-Nov A.YVSFGPHAGK.L "sp|P50914|RL14_HUMAN,tr|E7EPB3|E7EPB3_HUMAN" 2 1061.5294 1.13 46463 12165 2 1061.530679 531.772 60S ribosomal protein L14 OS=Homo sapiens OX=9606 GN=RPL14 PE=1 SV=4 8.6 2404.8 - 296152 - - - 1.1766 - 1.933 0.434 - 293.3 1 1 0 0.0012 10 0 0 0 8.30E+06 7.32E+06 - - - 4.0858 0.8336 221125_WJC_METTL3_EV_vs_WT_F04.12166.12166.2 0.0245 18-Jun L.GGHGPSFPLK.G sp|P13010|XRCC5_HUMAN 1 995.5189 1.01 46464 12166 2 995.520106 498.7667 X-ray repair cross-complementing protein 5 OS=Homo sapiens OX=9606 GN=XRCC5 PE=1 SV=3 8.76 2405 - 248303 - - - 1.2466 - 1.336 0.252 - 89.9 1 1 0 0.0012 10 0 0 0 6.13E+06 6.09E+06 - - - 1.7105 0.992 221125_WJC_METTL3_EV_vs_WT_F04.12168.12168.2 0.42 18-Sep K.DYTVTQVPPK.H "sp|Q8N5Z5|KCD17_HUMAN,tr|A0A087WX35|A0A087WX35_HUMAN,tr|H0Y731|H0Y731_HUMAN" 3 1146.5921 14.65 46465 12168 2 1146.592864 574.3033 BTB\POZ domain-containing protein KCTD17 OS=Homo sapiens OX=9606 GN=KCTD17 PE=1 SV=3 5.83 2405.2 - 595974 - - - 0.675 - 1.306 0.147 - 209.8 1 2 0 0.0008 10 0 0 0 2.30E+07 1.57E+06 - - - 0.8717 0.9999 221125_WJC_METTL3_EV_vs_WT_F04.12172.12172.2 0.0164 18-Sep R.TEAESWYQTK.Y "sp|P13647|K2C5_HUMAN,tr|H0YI76|H0YI76_HUMAN,tr|H0YIN9|H0YIN9_HUMAN" 3 1241.5564 502.87 46468 12172 2 1241.556142 621.7855 "Keratin, type II cytoskeletal 5 OS=Homo sapiens OX=9606 GN=KRT5 PE=1 SV=3" 4.53 2405.6 - 2.19E+06 - - - -0.2336 - 2.07 0.468 - 248.4 1 2 0 -0.0003 10 0 0 0 9.43E+08 1.87E+06 - - - 4.5284 0.999 221125_WJC_METTL3_EV_vs_WT_F04.12174.12174.2 0.057 14-Aug R.EQEVNILK[136.11].K sp|P35579|MYH9_HUMAN 1 979.543 1.05 46470 12174 2 979.542528 490.7788 Myosin-9 OS=Homo sapiens OX=9606 GN=MYH9 PE=1 SV=4 4.53 2405.8 - 915015 - - - -0.442 - 1.568 0.265 - 283 1 2 0 -0.0004 8 0 0 0 1.50E+07 1.43E+07 - - - 2.3547 0.9997 221125_WJC_METTL3_EV_vs_WT_F04.12176.12176.2 4.82E-06 13/26 K.EAVAPVQEESDLEK[136.11].K "sp|Q13409|DC1I2_HUMAN,tr|E7EUM4|E7EUM4_HUMAN,tr|E7ET01|E7ET01_HUMAN,tr|E7ERR6|E7ERR6_HUMAN,tr|E7ETL8|E7ETL8_HUMAN,tr|E7EV09|E7EV09_HUMAN,tr|E9PGG1|E9PGG1_HUMAN,tr|E7ESD3|E7ESD3_HUMAN,tr|E7ERH4|E7ERH4_HUMAN,tr|E7EQU2|E7EQU2_HUMAN,tr|E7EQL5|E7EQL5_HUMAN,tr|E7EU01|E7EU01_HUMAN,tr|E7EMU4|E7EMU4_HUMAN" 13 1550.7555 1.27 46472 12176 2 1550.752366 776.385 Cytoplasmic dynein 1 intermediate chain 2 OS=Homo sapiens OX=9606 GN=DYNC1I2 PE=1 SV=3 3.91 2406.1 - 623352 - - - -2.0422 - 2.349 0.503 - 543.7 1 2 0 -0.0032 14 0 0 0 9.58E+06 7.52E+06 - - - 4.8982 0.9999 221125_WJC_METTL3_EV_vs_WT_F04.12178.12178.2 1.01E-05 13/26 K.EAVAPVQEESDLEK.K "sp|Q13409|DC1I2_HUMAN,tr|E7EUM4|E7EUM4_HUMAN,tr|E7ET01|E7ET01_HUMAN,tr|E7ERR6|E7ERR6_HUMAN,tr|E7ETL8|E7ETL8_HUMAN,tr|E7EV09|E7EV09_HUMAN,tr|E9PGG1|E9PGG1_HUMAN,tr|E7ESD3|E7ESD3_HUMAN,tr|E7ERH4|E7ERH4_HUMAN,tr|E7EQU2|E7EQU2_HUMAN,tr|E7EQL5|E7EQL5_HUMAN,tr|E7EU01|E7EU01_HUMAN,tr|E7EMU4|E7EMU4_HUMAN" 13 1542.7413 1.27 46474 12178 2 1542.739537 772.3779 Cytoplasmic dynein 1 intermediate chain 2 OS=Homo sapiens OX=9606 GN=DYNC1I2 PE=1 SV=3 3.91 2406.3 - 591827 - - - -1.1642 - 2.282 0.523 - 558.5 1 2 0 -0.0018 14 0 0 0 9.58E+06 7.52E+06 - - - 4.9737 0.9999 221125_WJC_METTL3_EV_vs_WT_F04.12179.12179.2 1.28E-06 20-Nov R.VTQSNFAVGYK.T "sp|P21796|VDAC1_HUMAN,tr|C9JI87|C9JI87_HUMAN" 2 1212.6139 1.32 46475 12179 2 1212.614148 607.3142 Voltage-dependent anion-selective channel protein 1 OS=Homo sapiens OX=9606 GN=VDAC1 PE=1 SV=2 8.56 2406.4 - 465171 - - - 0.2144 - 2.311 0.546 - 640.5 1 2 0 0.0003 11 0 0 0 3.57E+08 2.70E+08 - - - 5.3398 0.9967 221125_WJC_METTL3_EV_vs_WT_F04.12181.12181.3 0.0588 Aug-44 R.ALEESNYELEGK.L "sp|P13645|K1C10_HUMAN,tr|A0A1B0GVI3|A0A1B0GVI3_HUMAN" 2 1380.6409 7.61 46477 12181 3 1380.639276 461.2209 "Keratin, type I cytoskeletal 10 OS=Homo sapiens OX=9606 GN=KRT10 PE=1 SV=6" 4.09 2406.7 - 372374 - - - -1.169 - 1.295 0.296 - 95.1 1 2 0 -0.0016 12 0 0 0 1.81E+07 2.38E+06 - - - 2.5562 0.9992 221125_WJC_METTL3_EV_vs_WT_F04.12182.12182.2 0.00312 14-Jul R.FDLQNPSR[166.11].M sp|Q92922|SMRC1_HUMAN 1 985.4857 2.87 46478 12182 2 985.484214 493.7501 SWI\SNF complex subunit SMARCC1 OS=Homo sapiens OX=9606 GN=SMARCC1 PE=1 SV=3 5.84 2406.8 - 364728 - - - -1.4714 - 1.597 0.344 - 165.3 1 2 0 -0.0014 8 0 0 0 3.80E+07 1.33E+07 - - - 2.9932 0.9988 221125_WJC_METTL3_EV_vs_WT_F04.12184.12184.2 0.308 16-Jul K.ELTLLGKPK.R "sp|Q00059|TFAM_HUMAN,tr|H7BYN3|H7BYN3_HUMAN" 2 997.6172 1.26 46480 12184 2 997.616991 499.8159 "Transcription factor A, mitochondrial OS=Homo sapiens OX=9606 GN=TFAM PE=1 SV=1" 8.69 2407.1 - 257608 - - - -0.1915 - 1.584 0.244 - 153 1 2 0 -0.0002 9 0 0 0 3.20E+06 2.54E+06 - - - 2.1738 0.9982 221125_WJC_METTL3_EV_vs_WT_F04.12186.12186.2 0.0354 16-Aug K.ELTLLGK[136.11]PK[136.11].R "sp|Q00059|TFAM_HUMAN,tr|H7BYN3|H7BYN3_HUMAN" 2 1013.6456 1.26 46482 12186 2 1013.6452 507.8301 "Transcription factor A, mitochondrial OS=Homo sapiens OX=9606 GN=TFAM PE=1 SV=1" 8.69 2407.4 - 197649 - - - -0.3769 - 1.37 0.263 - 175.4 1 2 0 -0.0004 9 0 0 0 3.20E+06 2.54E+06 - - - 1.8942 0.9999 221125_WJC_METTL3_EV_vs_WT_F04.12189.12189.3 0.000983 15/40 K.AYPLADAHLTK.K "sp|P55769|NH2L1_HUMAN,tr|B1AHD1|B1AHD1_HUMAN,tr|A0A3B3IUA2|A0A3B3IUA2_HUMAN" 3 1198.6346 0.45 46483 12189 3 1198.631492 400.5522 NHP2-like protein 1 OS=Homo sapiens OX=9606 GN=SNU13 PE=1 SV=3 6.79 2407.7 - 3.48E+06 - - - -2.6121 - 2.602 0.463 - 247.2 1 2 0 -0.0031 11 0 0 0 8.30E+07 1.83E+08 - - - 6.4178 0.9997 221125_WJC_METTL3_EV_vs_WT_F04.12191.12191.2 0.000526 16-Oct R.EEQFNSTFR.V "sp|P01859|IGHG2_HUMAN,tr|A0A286YEY4|A0A286YEY4_HUMAN" 2 1156.5149 5732 46485 12191 2 1156.512479 579.2647 Immunoglobulin heavy constant gamma 2 OS=Homo sapiens OX=9606 GN=IGHG2 PE=1 SV=2 4.53 2407.9 - 1.77E+06 - - - -2.0951 - 1.805 0.53 - 557.1 1 2 0 -0.0024 9 0 0 0 6.05E+08 1.06E+05 - - - 4.6633 0.9996 221125_WJC_METTL3_EV_vs_WT_F04.12193.12193.2 0.000244 18-Nov K.TSSQPGFLER.L sp|Q9BTV4|TMM43_HUMAN 1 1120.5513 1.04 46487 12193 2 1120.549244 561.2829 Transmembrane protein 43 OS=Homo sapiens OX=9606 GN=TMEM43 PE=1 SV=1 5.66 2408.2 - 1.08E+06 - - - -1.8232 - 1.994 0.411 - 378.7 1 2 0 -0.002 10 0 0 0 2.35E+07 2.25E+07 - - - 4.0024 0.9998 221125_WJC_METTL3_EV_vs_WT_F04.12195.12195.2 3.18E-05 22-Dec R.SNLYIAESTSGR[166.11].G "sp|Q9NWU5|RM22_HUMAN,tr|E7ESL0|E7ESL0_HUMAN,tr|J3KQY1|J3KQY1_HUMAN" 3 1306.6393 4.16 46489 12195 2 1306.638288 654.3269 "39S ribosomal protein L22, mitochondrial OS=Homo sapiens OX=9606 GN=MRPL22 PE=1 SV=1" 5.72 2408.4 - 849437 - - - -0.747 - 2.298 0.373 - 455.5 1 2 0 -0.001 12 0 0 0 1.22E+08 2.94E+07 - - - 3.9849 0.9998 221125_WJC_METTL3_EV_vs_WT_F04.12196.12196.2 6.05E-09 13/28 R.LLSGPSQESPQTLGK.E "sp|Q9BWE0|REPI1_HUMAN,tr|C9JZE3|C9JZE3_HUMAN,tr|E7EVL6|E7EVL6_HUMAN,tr|C9JYJ8|C9JYJ8_HUMAN" 4 1540.8097 1.1 46490 12196 2 1540.806948 771.4121 Replication initiator 1 OS=Homo sapiens OX=9606 GN=REPIN1 PE=1 SV=1 6 2408.6 - 823411 - - - -1.7776 - 2.527 0.592 - 594.5 1 2 0 -0.0027 15 0 0 0 1.42E+07 1.29E+07 - - - 5.6918 1 221125_WJC_METTL3_EV_vs_WT_F04.12201.12201.3 5.93E-06 15/44 R.VAYVSFGPHAGK.L "sp|P50914|RL14_HUMAN,tr|E7EPB3|E7EPB3_HUMAN" 2 1231.635 1.3 46494 12201 3 1231.633131 411.5523 60S ribosomal protein L14 OS=Homo sapiens OX=9606 GN=RPL14 PE=1 SV=4 8.57 2409.2 - 3.89E+06 - - - -1.4826 - 2.565 0.463 - 239 1 2 0 -0.0018 12 0 0 0 1.23E+08 9.44E+07 - - - 6.3125 0.9918 221125_WJC_METTL3_EV_vs_WT_F04.12204.12204.2 0.0776 14-Jul R.EQEVNILK.K sp|P35579|MYH9_HUMAN 1 971.5288 1.05 46496 12204 2 971.527268 486.7717 Myosin-9 OS=Homo sapiens OX=9606 GN=MYH9 PE=1 SV=4 4.53 2409.5 - 1.47E+06 - - - -1.5368 - 1.421 0.132 - 212.3 1 2 0 -0.0015 8 0 0 0 1.50E+07 1.43E+07 - - - 1.0752 1 221125_WJC_METTL3_EV_vs_WT_F04.12205.12205.2 8.43E-05 20-Dec K.SEMEVQDAELK[136.11].A sp|Q9UQ80|PA2G4_HUMAN 1 1285.5951 0.02 46497 12205 2 1285.596581 643.8048 Proliferation-associated protein 2G4 OS=Homo sapiens OX=9606 GN=PA2G4 PE=1 SV=3 4 2409.5 - 2.48E+06 - - - 1.1263 - 2.536 0.573 - 592.4 1 2 0 0.0014 11 0 0 0 7.32E+05 3.05E+07 - - - 5.7902 1 221125_WJC_METTL3_EV_vs_WT_F04.12207.12207.2 1.68E-10 16/26 R.ELEDATETADAMNR.E sp|P35579|MYH9_HUMAN 1 1564.6675 1.29 46499 12207 2 1565.685831 783.341 Myosin-9 OS=Homo sapiens OX=9606 GN=MYH9 PE=1 SV=4 3.83 2409.8 - 915491 - - - 650.8188 - 2.761 0.702 - 672.8 1 2 0 1.0183 14 0 0 0 7.44E+07 5.76E+07 - - - 6.4548 0.9996 221125_WJC_METTL3_EV_vs_WT_F04.12208.12208.2 0.00715 16-Oct R.QINDIQLSR[166.11].D "sp|Q13347|EIF3I_HUMAN,tr|A0A7I2YQT9|A0A7I2YQT9_HUMAN,tr|A0A7I2V613|A0A7I2V613_HUMAN,tr|A0A7I2V3N2|A0A7I2V3N2_HUMAN,tr|A0A7I2YQU2|A0A7I2YQU2_HUMAN,tr|A0A7I2YQI6|A0A7I2YQI6_HUMAN,tr|A0A7I2YQF8|A0A7I2YQF8_HUMAN,tr|Q5TFK1|Q5TFK1_HUMAN,tr|A0A7I2V3U3|A0A7I2V3U3_HUMAN,tr|A0A7I2V607|A0A7I2V607_HUMAN,tr|A0A7I2V640|A0A7I2V640_HUMAN,tr|A0A7P0MRT9|A0A7P0MRT9_HUMAN,tr|A0A7I2V3K6|A0A7I2V3K6_HUMAN,tr|A0A7I2V4S8|A0A7I2V4S8_HUMAN,tr|A0A7I2V5V8|A0A7I2V5V8_HUMAN,tr|A0A7I2V2M3|A0A7I2V2M3_HUMAN,tr|A0A7I2V4C2|A0A7I2V4C2_HUMAN,tr|A0A7I2YQP9|A0A7I2YQP9_HUMAN,tr|A0A7I2YQI2|A0A7I2YQI2_HUMAN,tr|A0A7I2YQC8|A0A7I2YQC8_HUMAN,tr|A0A7I2V685|A0A7I2V685_HUMAN" 21 1095.5912 1.16 46500 12208 2 1095.593351 548.8029 Eukaryotic translation initiation factor 3 subunit I OS=Homo sapiens OX=9606 GN=EIF3I PE=1 SV=1 5.84 2409.9 - 875688 - - - 1.9706 - 2.329 0.36 - 538.2 1 2 0 0.0022 9 0 0 0 5.97E+07 5.13E+07 - - - 4.1452 0.9548 221125_WJC_METTL3_EV_vs_WT_F04.12210.12210.3 0.00535 16/40 K.AYPLADAHLTK[136.11].K "sp|P55769|NH2L1_HUMAN,tr|B1AHD1|B1AHD1_HUMAN,tr|A0A3B3IUA2|A0A3B3IUA2_HUMAN" 3 1206.6488 0.21 46501 12210 3 1207.64688 403.2236 NHP2-like protein 1 OS=Homo sapiens OX=9606 GN=SNU13 PE=1 SV=3 6.79 2410.1 - 1.12E+06 - - - 827.1313 - 2.482 0.352 - 280.4 1 2 0 0.9981 11 0 0 0 3.32E+07 1.59E+08 - - - 4.7705 0.9439 221125_WJC_METTL3_EV_vs_WT_F04.12212.12212.2 0.000405 14-Oct L.SAANLHLR.T sp|Q6P2Q9|PRP8_HUMAN 1 880.4879 1.06 46502 12212 2 880.484906 441.2512 Pre-mRNA-processing-splicing factor 8 OS=Homo sapiens OX=9606 GN=PRPF8 PE=1 SV=2 9.49 2410.3 - 1.43E+06 - - - -3.3993 - 2.042 0.428 - 520.4 1 1 0 -0.003 8 0 0 0 2.87E+07 2.71E+07 - - - 4.3544 0.9992 221125_WJC_METTL3_EV_vs_WT_F04.12215.12215.2 0.000102 18-Oct K.GSEEELADIK[136.11].Q sp|Q8WXX5|DNJC9_HUMAN 1 1097.5332 1.54 46505 12215 2 1097.531941 549.7739 DnaJ homolog subfamily C member 9 OS=Homo sapiens OX=9606 GN=DNAJC9 PE=1 SV=1 4 2410.7 - 1.37E+06 - - - -1.1325 - 1.899 0.264 - 399.1 1 2 0 -0.0012 10 0 0 0 2.54E+07 1.65E+07 - - - 2.7807 0.958 221125_WJC_METTL3_EV_vs_WT_F04.12217.12217.2 1.69 12-Jul K.FNHWELK[136.11].G sp|P07814|SYEP_HUMAN 1 980.496 2.4 46507 12217 2 980.491237 491.2553 Bifunctional glutamate\proline--tRNA ligase OS=Homo sapiens OX=9606 GN=EPRS1 PE=1 SV=5 6.75 2411 - 731057 - - - -4.8078 - 1.258 0.246 - 184.2 1 2 0 -0.0047 7 0 0 0 1.29E+07 5.39E+06 - - - 1.5837 0.9999 221125_WJC_METTL3_EV_vs_WT_F04.12220.12220.2 8.43E-07 13/24 R.QAGAEALSQAVAR.Y sp|Q92616|GCN1_HUMAN 1 1270.663 1.07 46508 12220 2 1270.662202 636.3388 eIF-2-alpha kinase activator GCN1 OS=Homo sapiens OX=9606 GN=GCN1 PE=1 SV=6 6 2411.4 - 1.13E+06 - - - -0.5989 - 2.601 0.524 - 751.6 1 2 0 -0.0008 13 0 0 0 1.74E+07 1.62E+07 - - - 5.3644 0.9998 221125_WJC_METTL3_EV_vs_WT_F04.12222.12222.2 0.000262 24-Dec R.GLQPGTTDQDLVK.L "sp|Q15434|RBMS2_HUMAN,tr|F8VQS9|F8VQS9_HUMAN,tr|A0A1W2PQV1|A0A1W2PQV1_HUMAN,tr|F8W1T6|F8W1T6_HUMAN" 4 1370.7042 2.51 46510 12222 2 1370.702128 686.3594 "RNA-binding motif, single-stranded-interacting protein 2 OS=Homo sapiens OX=9606 GN=RBMS2 PE=1 SV=1" 4.21 2411.5 - 5.78E+06 - - - -1.4817 - 2.035 0.483 - 380.3 1 2 0 -0.002 13 0 0 0 1.33E+08 5.29E+07 - - - 4.4313 0.9997 221125_WJC_METTL3_EV_vs_WT_F04.12223.12223.2 0.000301 16-Dec R.QINDIQLSR.D "sp|Q13347|EIF3I_HUMAN,tr|A0A7I2YQT9|A0A7I2YQT9_HUMAN,tr|A0A7I2V613|A0A7I2V613_HUMAN,tr|A0A7I2V3N2|A0A7I2V3N2_HUMAN,tr|A0A7I2YQU2|A0A7I2YQU2_HUMAN,tr|A0A7I2YQI6|A0A7I2YQI6_HUMAN,tr|A0A7I2YQF8|A0A7I2YQF8_HUMAN,tr|Q5TFK1|Q5TFK1_HUMAN,tr|A0A7I2V3U3|A0A7I2V3U3_HUMAN,tr|A0A7I2V607|A0A7I2V607_HUMAN,tr|A0A7I2V640|A0A7I2V640_HUMAN,tr|A0A7P0MRT9|A0A7P0MRT9_HUMAN,tr|A0A7I2V3K6|A0A7I2V3K6_HUMAN,tr|A0A7I2V4S8|A0A7I2V4S8_HUMAN,tr|A0A7I2V5V8|A0A7I2V5V8_HUMAN,tr|A0A7I2V2M3|A0A7I2V2M3_HUMAN,tr|A0A7I2V4C2|A0A7I2V4C2_HUMAN,tr|A0A7I2YQP9|A0A7I2YQP9_HUMAN,tr|A0A7I2YQI2|A0A7I2YQI2_HUMAN,tr|A0A7I2YQC8|A0A7I2YQC8_HUMAN,tr|A0A7I2V685|A0A7I2V685_HUMAN" 21 1085.5829 1.16 46511 12223 2 1085.581105 543.7987 Eukaryotic translation initiation factor 3 subunit I OS=Homo sapiens OX=9606 GN=EIF3I PE=1 SV=1 5.84 2411.6 - 1.59E+06 - - - -1.6738 - 2.205 0.398 - 830.1 1 2 0 -0.0018 9 0 0 0 5.97E+07 5.13E+07 - - - 4.2677 0.9987 221125_WJC_METTL3_EV_vs_WT_F04.12224.12224.2 0.00557 18-Sep R.AISAANLHLR.T sp|Q6P2Q9|PRP8_HUMAN 1 1064.6091 1.54 46512 12224 2 1064.606999 533.3118 Pre-mRNA-processing-splicing factor 8 OS=Homo sapiens OX=9606 GN=PRPF8 PE=1 SV=2 9.8 2411.8 - 780262 - - - -1.9519 - 1.713 0.303 - 232.4 1 2 0 -0.0021 10 0 0 0 9.21E+06 5.97E+06 - - - 2.7807 0.9999 221125_WJC_METTL3_EV_vs_WT_F04.12228.12228.3 5.36E-06 Nov-36 K.KPEMFETAIK.E "sp|P78347|GTF2I_HUMAN,tr|A0A494C1K3|A0A494C1K3_HUMAN" 2 1192.6162 1.44 46514 12228 3 1192.612028 398.546 General transcription factor II-I OS=Homo sapiens OX=9606 GN=GTF2I PE=1 SV=2 6.14 2412.3 - 1.73E+06 - - - -3.4948 - 2.248 0.546 - 124.8 1 2 0 -0.0042 10 0 0 0 3.82E+08 2.66E+08 - - - 6.9919 0.999 221125_WJC_METTL3_EV_vs_WT_F04.12230.12230.2 0.000112 20-Dec R.QELILSNSEDK[136.11].S "sp|P53621|COPA_HUMAN,tr|A0A3B3ISC6|A0A3B3ISC6_HUMAN,tr|A0A3B3ITV3|A0A3B3ITV3_HUMAN,tr|A0A3B3IS84|A0A3B3IS84_HUMAN,tr|A0A3B3IU89|A0A3B3IU89_HUMAN,tr|A0A3B3ISK1|A0A3B3ISK1_HUMAN,tr|A0A3B3IT15|A0A3B3IT15_HUMAN" 7 1282.6496 0.39 46516 12230 2 1282.644557 642.3321 Coatomer subunit alpha OS=Homo sapiens OX=9606 GN=COPA PE=1 SV=2 4.14 2412.4 - 2.06E+06 - - - -3.9403 - 2.48 0.485 - 727.5 1 2 0 -0.0051 11 0 0 0 1.87E+07 4.75E+07 - - - 5.0787 0.9994 221125_WJC_METTL3_EV_vs_WT_F04.12231.12231.2 0.0208 16-Sep K.NFSTVDIQK[136.11].N "sp|P43246|MSH2_HUMAN,tr|A0A2R8YG02|A0A2R8YG02_HUMAN,tr|A0A2R8Y7S8|A0A2R8Y7S8_HUMAN,tr|E9PHA6|E9PHA6_HUMAN,tr|A0A2R8YFH0|A0A2R8YFH0_HUMAN,tr|A0A2R8Y6P0|A0A2R8Y6P0_HUMAN" 6 1058.5488 0.75 46517 12231 2 1058.548607 530.2817 DNA mismatch repair protein Msh2 OS=Homo sapiens OX=9606 GN=MSH2 PE=1 SV=1 5.84 2412.6 - 1.03E+06 - - - -0.1587 - 1.607 0.328 - 214.9 1 2 0 -0.0002 9 0 0 0 2.49E+07 3.32E+07 - - - 2.8359 0.9993 221125_WJC_METTL3_EV_vs_WT_F04.12235.12235.2 0.0173 13/20 K.NITLDDASAPR[166.11].L "sp|O75534|CSDE1_HUMAN,tr|E9PLT0|E9PLT0_HUMAN" 2 1181.5916 0.68 46519 12235 2 1181.589997 591.8031 Cold shock domain-containing protein E1 OS=Homo sapiens OX=9606 GN=CSDE1 PE=1 SV=2 4.21 2413.1 - 1.72E+06 - - - -1.3448 - 1.856 0.316 - 428.7 1 2 0 -0.0016 11 0 0 0 4.42E+07 6.47E+07 - - - 3.0475 0.9998 221125_WJC_METTL3_EV_vs_WT_F04.12237.12237.2 1.85E-06 13/22 R.SNLYIAESTSGR.G "sp|Q9NWU5|RM22_HUMAN,tr|E7ESL0|E7ESL0_HUMAN,tr|J3KQY1|J3KQY1_HUMAN" 3 1296.631 3.64 46521 12237 2 1296.630051 649.3228 "39S ribosomal protein L22, mitochondrial OS=Homo sapiens OX=9606 GN=MRPL22 PE=1 SV=1" 5.72 2413.3 - 2.45E+06 - - - -0.7273 - 2.449 0.431 - 592.7 1 2 0 -0.0009 12 0 0 0 1.22E+08 3.36E+07 - - - 4.5808 0.9999 221125_WJC_METTL3_EV_vs_WT_F04.12238.12238.3 9.94E-05 Dec-52 R.ELEDATETADAMNR.E sp|P35579|MYH9_HUMAN 1 1564.6675 1.28 46522 12238 3 1564.666409 522.5631 Myosin-9 OS=Homo sapiens OX=9606 GN=MYH9 PE=1 SV=4 3.83 2413.4 - 1.01E+06 - - - -0.7075 - 1.88 0.433 - 178.3 1 2 0 -0.0011 14 0 0 0 1.38E+07 1.08E+07 - - - 5.0448 0.9949 221125_WJC_METTL3_EV_vs_WT_F04.12239.12239.2 0.0396 18-Aug R.INIPPPSVNR[166.11].T "sp|Q00341|VIGLN_HUMAN,tr|A0A024R4E5|A0A024R4E5_HUMAN,tr|H7C0A4|H7C0A4_HUMAN,tr|H0Y394|H0Y394_HUMAN" 4 1115.6327 1.09 46523 12239 2 1115.631193 558.8236 Vigilin OS=Homo sapiens OX=9606 GN=HDLBP PE=1 SV=2 9.75 2413.6 - 912474 - - - -1.3176 - 1.422 0.177 - 233.4 1 2 0 -0.0015 10 0 0 0 1.42E+07 1.31E+07 - - - 1.3306 0.997 221125_WJC_METTL3_EV_vs_WT_F04.12240.12240.3 0.0449 Dec-52 R.SLDPADERDDVLAK.R "sp|Q8WXI9|P66B_HUMAN,tr|A0A0U1RR34|A0A0U1RR34_HUMAN,tr|A0A0U1RRM1|A0A0U1RRM1_HUMAN,tr|A0A0U1RRK3|A0A0U1RRK3_HUMAN" 4 1542.7526 2.91 46524 12240 3 1542.752588 515.2581 Transcriptional repressor p66-beta OS=Homo sapiens OX=9606 GN=GATAD2B PE=1 SV=1 4.04 2413.7 - 712610 - - - 0.0143 - 1.707 0.329 - 111.5 1 2 1 0 14 0 0 0 1.70E+07 5.83E+06 - - - 3.6291 0.9799 221125_WJC_METTL3_EV_vs_WT_F04.12241.12241.2 0.1 18-Jul R.INIPPPSVNR.T "sp|Q00341|VIGLN_HUMAN,tr|A0A024R4E5|A0A024R4E5_HUMAN,tr|H7C0A4|H7C0A4_HUMAN,tr|H0Y394|H0Y394_HUMAN" 4 1105.6244 0.99 46525 12241 2 1105.621964 553.8195 Vigilin OS=Homo sapiens OX=9606 GN=HDLBP PE=1 SV=2 9.75 2413.8 - 500642 - - - -2.1969 - 1.491 0.081 - 149 1 2 0 -0.0024 10 0 0 0 1.11E+07 1.12E+07 - - - 0.7535 0.9998 221125_WJC_METTL3_EV_vs_WT_F04.12243.12243.2 0.000325 18-Nov K.EQNSPIYISR.L "sp|O14910|LIN7A_HUMAN,sp|Q9NUP9|LIN7C_HUMAN,sp|Q9HAP6|LIN7B_HUMAN,tr|H0YIA8|H0YIA8_HUMAN,tr|G3V1D4|G3V1D4_HUMAN,tr|H0YI92|H0YI92_HUMAN" 6 1205.6041 1.05 46526 12243 2 1205.602173 603.8093 Protein lin-7 homolog A OS=Homo sapiens OX=9606 GN=LIN7A PE=1 SV=2 6.1 2414 - 2.35E+06 - - - -1.5577 - 2.071 0.51 - 578.2 1 2 0 -0.0019 10 0 0 0 5.08E+07 4.84E+07 - - - 4.8394 1 221125_WJC_METTL3_EV_vs_WT_F04.12245.12245.2 1.01E-08 20-Dec R.DDTIYEDEDVK.E "sp|P14927|QCR7_HUMAN,tr|E5RHG9|E5RHG9_HUMAN,tr|B7Z2R2|B7Z2R2_HUMAN" 3 1340.562 1.45 46527 12245 2 1340.557696 671.2883 Cytochrome b-c1 complex subunit 7 OS=Homo sapiens OX=9606 GN=UQCRB PE=1 SV=2 3.66 2414.2 - 1.14E+06 - - - -3.189 - 2.523 0.661 - 655.7 1 2 0 -0.0043 11 0 0 0 2.64E+07 1.82E+07 - - - 6.4254 0.9998 221125_WJC_METTL3_EV_vs_WT_F04.12246.12246.2 0.018 20-Nov K.NITLDDASAPR.L "sp|O75534|CSDE1_HUMAN,tr|E9PLT0|E9PLT0_HUMAN" 2 1171.5833 0.68 46528 12246 2 1171.582634 586.7989 Cold shock domain-containing protein E1 OS=Homo sapiens OX=9606 GN=CSDE1 PE=1 SV=2 4.21 2414.4 - 1.29E+06 - - - -0.5821 - 2.298 0.411 - 353.3 1 2 0 -0.0007 11 0 0 0 4.42E+07 6.51E+07 - - - 4.3273 0.997 221125_WJC_METTL3_EV_vs_WT_F04.12247.12247.2 0.0158 18-Sep K.SAVGFDYQGK.T sp|Q14247|SRC8_HUMAN 1 1070.5033 0.84 46529 12247 2 1070.501455 536.2589 Src substrate cortactin OS=Homo sapiens OX=9606 GN=CTTN PE=1 SV=2 5.55 2414.5 - 1.03E+06 - - - -1.7001 - 1.388 0.265 - 162.3 1 2 0 -0.0018 10 0 0 0 1.66E+07 1.98E+07 - - - 1.9129 0.9516 221125_WJC_METTL3_EV_vs_WT_F04.12248.12248.3 0.573 Sep-36 R.LLSLDPSHER.A sp|O15460|P4HA2_HUMAN 1 1165.6091 0.53 46530 12248 3 1165.607144 389.5437 Prolyl 4-hydroxylase subunit alpha-2 OS=Homo sapiens OX=9606 GN=P4HA2 PE=1 SV=1 5.32 2414.6 - 558168 - - - -1.7098 - 1.589 0.108 - 96.1 1 2 0 -0.002 10 0 0 0 8.84E+06 1.66E+07 - - - 1.096 0.9801 221125_WJC_METTL3_EV_vs_WT_F04.12249.12249.3 0.109 Oct-36 K.LSNHVFNALK[136.11].Q "sp|O14730|RIOK3_HUMAN,tr|J3QQL5|J3QQL5_HUMAN,tr|B4E1Q4|B4E1Q4_HUMAN" 3 1149.6386 0.4 46531 12249 3 1149.636205 384.2201 Serine\threonine-protein kinase RIO3 OS=Homo sapiens OX=9606 GN=RIOK3 PE=1 SV=2 8.76 2414.8 - 547604 - - - -2.0772 - 1.747 0.144 - 73.1 1 2 0 -0.0024 10 0 0 0 3.47E+06 8.58E+06 - - - 1.7741 1 221125_WJC_METTL3_EV_vs_WT_F04.12251.12251.2 2.04E-07 15/24 K.ITESVAETAQTIK[136.11].K sp|Q96A49|SYAP1_HUMAN 1 1397.7493 1.27 46532 12251 2 1397.745727 699.8819 Synapse-associated protein 1 OS=Homo sapiens OX=9606 GN=SYAP1 PE=1 SV=1 4.53 2415 - 4.52E+07 - - - -2.5741 - 3.008 0.578 - 767.3 1 2 0 -0.0036 13 0 0 0 1.65E+09 1.30E+09 - - - 6.1354 0.9974 221125_WJC_METTL3_EV_vs_WT_F04.12254.12254.3 0.134 Aug-48 K.ITESVAETAQTIK[136.11].K sp|Q96A49|SYAP1_HUMAN 1 1397.7493 1.39 46534 12254 3 1397.747467 466.9237 Synapse-associated protein 1 OS=Homo sapiens OX=9606 GN=SYAP1 PE=1 SV=1 4.53 2415.2 - 7.05E+06 - - - -1.3293 - 2.069 0.222 - 121.6 3 2 0 -0.0019 13 0 0 0 2.44E+08 1.76E+08 - - - 2.765 0.9993 221125_WJC_METTL3_EV_vs_WT_F04.12256.12256.2 0.00129 18-Sep R.RLEIPSGGAD.- sp|Q96AV8|E2F7_HUMAN 1 1013.5142 1.98 46536 12256 2 1013.513072 507.7644 Transcription factor E2F7 OS=Homo sapiens OX=9606 GN=E2F7 PE=1 SV=3 4.67 2415.4 - 701206 - - - -1.0873 - 1.708 0.319 - 266.4 1 2 0 -0.0011 10 0 0 0 1.38E+07 6.99E+06 - - - 2.891 0.9993 221125_WJC_METTL3_EV_vs_WT_F04.12258.12258.3 0.00299 Nov-36 K.EVC[160.03]INPYHYK[136.11].R "sp|Q99717|SMAD5_HUMAN,sp|Q15797|SMAD1_HUMAN,tr|D6RBB4|D6RBB4_HUMAN,tr|D6RD62|D6RD62_HUMAN" 4 1329.6267 1.12 46538 12258 3 1329.623114 444.2162 Mothers against decapentaplegic homolog 5 OS=Homo sapiens OX=9606 GN=SMAD5 PE=1 SV=1 6.83 2415.6 - 556598 - - - -2.703 - 1.62 0.405 - 134.6 1 2 0 -0.0036 10 0 0 0 1.90E+07 1.71E+07 - - - 4.4632 0.9862 221125_WJC_METTL3_EV_vs_WT_F04.12262.12262.2 6.49E-06 22-Nov K.ELTSTC[160.03]SPIISK[136.11].P sp|P34932|HSP74_HUMAN 1 1342.6894 0.02 46540 12262 2 1342.691018 672.352 Heat shock 70 kDa protein 4 OS=Homo sapiens OX=9606 GN=HSPA4 PE=1 SV=4 6.09 2416.2 - 1.59E+06 - - - 1.2289 - 2.228 0.444 - 333.3 1 1 0 0.0016 12 0 0 0 7.39E+05 3.68E+07 - - - 4.4277 0.9995 221125_WJC_METTL3_EV_vs_WT_F04.12263.12263.3 0.000119 14/52 K.ADLATAPPHVTVVR[166.11].- sp|Q8N1G4|LRC47_HUMAN 1 1455.8073 0.68 46541 12263 3 1455.806423 486.2764 Leucine-rich repeat-containing protein 47 OS=Homo sapiens OX=9606 GN=LRRC47 PE=1 SV=1 6.79 2416.3 - 629422 - - - -0.6251 - 2.343 0.273 - 226.4 1 2 0 -0.0009 14 0 0 0 2.83E+07 4.15E+07 - - - 3.8461 0.9984 221125_WJC_METTL3_EV_vs_WT_F04.12264.12264.3 0.0881 Dec-44 K.IQELAHELAAAK[136.11].A sp|O75381|PEX14_HUMAN 1 1300.7231 0.82 46542 12264 3 1300.718287 434.5816 Peroxisomal membrane protein PEX14 OS=Homo sapiens OX=9606 GN=PEX14 PE=1 SV=1 5.4 2416.5 - 758054 - - - -3.6626 - 2.325 0.31 - 188.1 1 2 0 -0.0048 12 0 0 0 9.70E+06 1.19E+07 - - - 4.3335 0.9997 221125_WJC_METTL3_EV_vs_WT_F04.12265.12265.2 6.35E-05 13/24 R.QDPQSTAAATVLK.R "sp|Q8WV92|MITD1_HUMAN,tr|F8WED5|F8WED5_HUMAN,tr|B8ZZL5|B8ZZL5_HUMAN,tr|A0A1W2PP14|A0A1W2PP14_HUMAN" 4 1328.6936 2.03 46543 12265 2 1328.694901 665.3541 MIT domain-containing protein 1 OS=Homo sapiens OX=9606 GN=MITD1 PE=1 SV=1 5.84 2416.6 - 757144 - - - 0.9829 - 2.208 0.414 - 630.4 1 2 0 0.0013 13 0 0 0 9.68E+06 4.77E+06 - - - 4.1313 0.9998 221125_WJC_METTL3_EV_vs_WT_F04.12266.12266.2 0.000801 16-Nov K.KVVNPLFEK.R "sp|P62424|RL7A_HUMAN,tr|Q5T8U3|Q5T8U3_HUMAN" 2 1072.6281 0.71 46544 12266 2 1072.627844 537.3213 60S ribosomal protein L7a OS=Homo sapiens OX=9606 GN=RPL7A PE=1 SV=2 8.59 2416.7 - 721864 - - - -0.221 - 2.146 0.404 - 401.5 1 2 0 -0.0002 9 0 0 0 1.08E+07 1.51E+07 - - - 4.234 0.9998 221125_WJC_METTL3_EV_vs_WT_F04.12267.12267.2 0.000147 16-Sep R.SNGVQLLQR.L "sp|Q9H3U1|UN45A_HUMAN,tr|A0A1W2PNX8|A0A1W2PNX8_HUMAN" 2 1013.5618 0.78 46545 12267 2 1013.561486 507.7882 Protein unc-45 homolog A OS=Homo sapiens OX=9606 GN=UNC45A PE=1 SV=1 9.47 2416.9 - 665212 - - - -0.3019 - 1.991 0.403 - 383 1 2 0 -0.0003 9 0 0 0 8.07E+06 1.03E+07 - - - 4.0097 1 221125_WJC_METTL3_EV_vs_WT_F04.12268.12268.2 1.52E-08 24-Dec K.VLQSDEYEEVEDK.T sp|O15397|IPO8_HUMAN 1 1581.7046 3.75 46546 12268 2 1581.700904 791.8596 Importin-8 OS=Homo sapiens OX=9606 GN=IPO8 PE=1 SV=2 3.77 2417 - 495297 - - - -2.3449 - 2.211 0.682 - 242.2 1 2 0 -0.0037 13 0 0 0 6.18E+06 1.65E+06 - - - 6.1135 0.8801 221125_WJC_METTL3_EV_vs_WT_F04.12269.12269.2 2.11 18-May K.TSSQPGFLER[166.11].L sp|Q9BTV4|TMM43_HUMAN 1 1130.5596 1 46547 12269 2 1130.556875 566.2871 Transmembrane protein 43 OS=Homo sapiens OX=9606 GN=TMEM43 PE=1 SV=1 5.66 2417.1 - 393660 - - - -2.3723 - 1.013 0.102 - 63 3 2 0 -0.0027 10 0 0 0 2.35E+07 2.34E+07 - - - -0.3835 0.9998 221125_WJC_METTL3_EV_vs_WT_F04.12272.12272.2 3.12E-06 20-Jul R.VTQSNFAVGYK[136.11].T "sp|P21796|VDAC1_HUMAN,tr|C9JI87|C9JI87_HUMAN" 2 1220.6281 1.32 46549 12272 2 1220.628378 611.3213 Voltage-dependent anion-selective channel protein 1 OS=Homo sapiens OX=9606 GN=VDAC1 PE=1 SV=2 8.56 2417.5 - 4.02E+06 - - - 0.2376 - 1.731 0.46 - 166.2 1 2 0 0.0003 11 0 0 0 3.55E+08 2.70E+08 - - - 3.9228 0.9928 221125_WJC_METTL3_EV_vs_WT_F04.12275.12275.3 0.138 Aug-36 K.EVC[160.03]INPYHYK.R "sp|Q99717|SMAD5_HUMAN,sp|Q15797|SMAD1_HUMAN,tr|D6RBB4|D6RBB4_HUMAN,tr|D6RD62|D6RD62_HUMAN" 4 1321.6125 1.12 46552 12275 3 1321.610307 441.5448 Mothers against decapentaplegic homolog 5 OS=Homo sapiens OX=9606 GN=SMAD5 PE=1 SV=1 6.83 2417.7 - 1.10E+06 - - - -1.6654 - 1.576 0.212 - 97.7 1 2 0 -0.0022 10 0 0 0 1.88E+07 1.68E+07 - - - 2.2315 1 221125_WJC_METTL3_EV_vs_WT_F04.12276.12276.3 7.08E-06 14/48 K.TLQEVTEMDSVKR.Y "sp|P58107|EPIPL_HUMAN,sp|P58107|EPIPL_HUMAN,sp|P58107|EPIPL_HUMAN,sp|P58107|EPIPL_HUMAN,tr|A0A075B730|A0A075B730_HUMAN,tr|A0A075B730|A0A075B730_HUMAN,tr|A0A075B730|A0A075B730_HUMAN,tr|A0A075B730|A0A075B730_HUMAN" 8 1534.7661 1.85 46553 12276 3 1534.763799 512.596 Epiplakin OS=Homo sapiens OX=9606 GN=EPPK1 PE=1 SV=3 4.68 2417.8 - 1.10E+06 - - - -1.5045 - 2.61 0.505 - 213 1 2 0 -0.0023 13 0 0 0 2.42E+07 1.31E+07 - - - 6.7707 0.9973 221125_WJC_METTL3_EV_vs_WT_F04.12277.12277.2 0.00157 14-Jul K.ADEGISFR[166.11].G "sp|Q06830|PRDX1_HUMAN,tr|A0A0A0MRQ5|A0A0A0MRQ5_HUMAN,tr|A0A0A0MSI0|A0A0A0MSI0_HUMAN" 3 903.4326 0.91 46554 12277 2 903.431481 452.7236 Peroxiredoxin-1 OS=Homo sapiens OX=9606 GN=PRDX1 PE=1 SV=1 4.37 2417.9 - 899294 - - - -1.201 - 1.659 0.164 - 232.1 1 2 0 -0.0011 8 0 0 0 1.17E+07 1.29E+07 - - - 1.7787 0.9999 221125_WJC_METTL3_EV_vs_WT_F04.12278.12278.2 0.000279 20-Dec R.QELILSNSEDK.S "sp|P53621|COPA_HUMAN,tr|A0A3B3ISC6|A0A3B3ISC6_HUMAN,tr|A0A3B3ITV3|A0A3B3ITV3_HUMAN,tr|A0A3B3IS84|A0A3B3IS84_HUMAN,tr|A0A3B3IU89|A0A3B3IU89_HUMAN,tr|A0A3B3ISK1|A0A3B3ISK1_HUMAN,tr|A0A3B3IT15|A0A3B3IT15_HUMAN" 7 1274.6354 0.39 46555 12278 2 1274.634871 638.325 Coatomer subunit alpha OS=Homo sapiens OX=9606 GN=COPA PE=1 SV=2 4.14 2418 - 839244 - - - -0.4237 - 2.563 0.433 - 734.3 1 2 0 -0.0005 11 0 0 0 1.87E+07 4.75E+07 - - - 4.7851 0.9987 221125_WJC_METTL3_EV_vs_WT_F04.12279.12279.3 0.0525 13/32 R.VHMTWVQPR[166.11].V "sp|Q9UNM6|PSD13_HUMAN,tr|J3KNQ3|J3KNQ3_HUMAN,tr|A0A087WUL9|A0A087WUL9_HUMAN" 3 1162.5945 0.32 46556 12279 3 1162.593085 388.5388 26S proteasome non-ATPase regulatory subunit 13 OS=Homo sapiens OX=9606 GN=PSMD13 PE=1 SV=2 9.73 2418.1 - 688733 - - - -1.2197 - 2.064 0.222 - 291.8 1 2 0 -0.0014 9 0 0 0 1.14E+07 3.54E+07 - - - 3.1986 0.9999 221125_WJC_METTL3_EV_vs_WT_F04.12283.12283.2 4.07E-05 26-Nov R.AAAEVNQDYGLDPK.L "sp|P07954|FUMH_HUMAN,tr|A0A804HKE6|A0A804HKE6_HUMAN,tr|A0A804HI24|A0A804HI24_HUMAN" 3 1489.7049 2.25 46560 12283 2 1489.704791 745.8597 "Fumarate hydratase, mitochondrial OS=Homo sapiens OX=9606 GN=FH PE=1 SV=3" 4.03 2418.6 - 246287 - - - -0.0651 - 2.212 0.495 - 295.2 1 2 0 -0.0001 14 0 0 0 6.32E+06 2.81E+06 - - - 4.6893 1 221125_WJC_METTL3_EV_vs_WT_F04.12285.12285.2 1.62E-07 16/18 K.KPEMFETAIK.E "sp|P78347|GTF2I_HUMAN,tr|A0A494C1K3|A0A494C1K3_HUMAN" 2 1192.6162 1.55 46561 12285 2 1192.614713 597.3154 General transcription factor II-I OS=Homo sapiens OX=9606 GN=GTF2I PE=1 SV=2 6.14 2418.9 - 1.13E+07 - - - -1.2435 - 3.285 0.618 - 836.3 1 2 0 -0.0015 10 0 0 0 2.51E+08 1.62E+08 - - - 6.925 0.9999 221125_WJC_METTL3_EV_vs_WT_F04.12287.12287.2 1.59E-05 20-Oct K.ASLENSLEETK.G "sp|P02533|K1C14_HUMAN,sp|P08779|K1C16_HUMAN,tr|K7ENW6|K7ENW6_HUMAN" 3 1219.5932 6031.4 46562 12287 2 1219.592244 610.8039 "Keratin, type I cytoskeletal 14 OS=Homo sapiens OX=9606 GN=KRT14 PE=1 SV=4" 4.25 2419.1 - 1.32E+07 - - - -0.7937 - 2.248 0.51 - 235.3 1 2 0 -0.001 11 0 0 0 8.09E+09 1.34E+06 - - - 4.9989 1 221125_WJC_METTL3_EV_vs_WT_F04.12288.12288.3 7.10E-06 17/40 R.FPGQLNADLR[166.11]K[136.11].L "sp|P04350|TBB4A_HUMAN,sp|Q9BVA1|TBB2B_HUMAN,sp|A6NNZ2|TBB8B_HUMAN,sp|P07437|TBB5_HUMAN,sp|Q13509|TBB3_HUMAN,sp|Q13885|TBB2A_HUMAN,sp|P68371|TBB4B_HUMAN,sp|Q9BUF5|TBB6_HUMAN,sp|Q3ZCM7|TBB8_HUMAN,sp|Q9H4B7|TBB1_HUMAN,tr|M0R2D3|M0R2D3_HUMAN,tr|A0A0B4J269|A0A0B4J269_HUMAN,tr|Q5ST81|Q5ST81_HUMAN,tr|Q5JP53|Q5JP53_HUMAN,tr|K7ESM5|K7ESM5_HUMAN,tr|A0A075B736|A0A075B736_HUMAN,tr|G3V2A3|G3V2A3_HUMAN,tr|Q5SQY0|Q5SQY0_HUMAN" 18 1275.7054 3.56 46563 12288 3 1275.703293 426.2424 Tubulin beta-4A chain OS=Homo sapiens OX=9606 GN=TUBB4A PE=1 SV=2 8.75 2419.1 - 2.69E+06 - - - -1.683 - 2.611 0.511 - 282 1 2 0 -0.0021 11 0 0 0 2.71E+08 7.62E+07 - - - 6.963 0.9999 221125_WJC_METTL3_EV_vs_WT_F04.12289.12289.2 1.26E-06 20-Nov R.EATTEFSVDAR.A "sp|P21333|FLNA_HUMAN,tr|Q60FE5|Q60FE5_HUMAN" 2 1224.5622 0.93 46564 12289 2 1224.561586 613.2884 Filamin-A OS=Homo sapiens OX=9606 GN=FLNA PE=1 SV=4 4.14 2419.3 - 1.08E+06 - - - -0.539 - 2.116 0.526 - 453 1 2 0 -0.0007 11 0 0 0 2.98E+07 3.19E+07 - - - 4.9535 0.9999 221125_WJC_METTL3_EV_vs_WT_F04.12290.12290.2 0.000492 22-Sep R.LTWHSC[160.03]PEDEAQ.- sp|Q13185|CBX3_HUMAN 1 1471.6038 - 46565 12290 2 1471.603059 736.8092 Chromobox protein homolog 3 OS=Homo sapiens OX=9606 GN=CBX3 PE=1 SV=4 4.13 2419.4 - 686202 - - - -0.4995 - 1.952 0.556 - 178.1 1 2 0 -0.0007 12 0 0 0 - - - - - 4.9073 0.9999 221125_WJC_METTL3_EV_vs_WT_F04.12292.12292.2 1.07E-05 22-Oct K.SPQSNSPVLLSR[166.11].L "sp|Q96FZ2|HMCES_HUMAN,tr|E7EMP6|E7EMP6_HUMAN,tr|D6RGK7|D6RGK7_HUMAN,tr|D6R9T3|D6R9T3_HUMAN,tr|D6RAZ3|D6RAZ3_HUMAN,tr|D6RAI0|D6RAI0_HUMAN" 6 1293.6916 0.04 46567 12292 2 1293.692468 647.8531 Abasic site processing protein HMCES OS=Homo sapiens OX=9606 GN=HMCES PE=1 SV=1 9.47 2419.6 - 303531 - - - 0.6447 - 2.2 0.509 - 350.2 1 2 0 0.0008 12 0 0 0 2.68E+05 6.95E+06 - - - 4.8748 0.9999 221125_WJC_METTL3_EV_vs_WT_F04.12296.12296.2 2.51E-06 20-Oct R.EATTEFSVDAR[166.11].A "sp|P21333|FLNA_HUMAN,tr|Q60FE5|Q60FE5_HUMAN" 2 1234.5705 1.1 46569 12296 2 1234.569304 618.2925 Filamin-A OS=Homo sapiens OX=9606 GN=FLNA PE=1 SV=4 4.14 2420.2 - 1.49E+06 - - - -0.9817 - 2.109 0.529 - 366.7 1 2 0 -0.0012 11 0 0 0 3.08E+07 2.79E+07 - - - 4.9665 0.9908 221125_WJC_METTL3_EV_vs_WT_F04.12297.12297.2 0.000115 16-Oct K.DMEIAELKK.N "sp|Q15643|TRIPB_HUMAN,tr|H0YJ97|H0YJ97_HUMAN" 2 1075.5583 0.88 46570 12297 2 1075.551699 538.7864 Thyroid receptor-interacting protein 11 OS=Homo sapiens OX=9606 GN=TRIP11 PE=1 SV=3 4.68 2420.3 - 902393 - - - -6.181 - 1.844 0.434 - 409.6 1 2 0 -0.0066 9 0 0 0 1.56E+07 1.76E+07 - - - 4.0148 0.9998 221125_WJC_METTL3_EV_vs_WT_F04.12299.12299.3 3.75E-06 14/40 K.TPQQLWYTHEK.K "sp|P17480|UBF1_HUMAN,tr|E9PKP7|E9PKP7_HUMAN" 2 1429.699 1.36 46572 12299 3 1429.696841 477.5736 Nucleolar transcription factor 1 OS=Homo sapiens OX=9606 GN=UBTF PE=1 SV=1 6.41 2420.4 - 2.18E+06 - - - -1.5199 - 2.261 0.367 - 304.5 1 2 0 -0.0022 11 0 0 0 2.25E+07 1.65E+07 - - - 4.9487 0.9998 221125_WJC_METTL3_EV_vs_WT_F04.12301.12301.2 0.000258 16-Jul K.DMEIAELK[136.11]K[136.11].N "sp|Q15643|TRIPB_HUMAN,tr|H0YJ97|H0YJ97_HUMAN" 2 1091.5867 0.92 46574 12301 2 1091.585783 546.8006 Thyroid receptor-interacting protein 11 OS=Homo sapiens OX=9606 GN=TRIP11 PE=1 SV=3 4.68 2420.6 - 1.03E+06 - - - -0.8831 - 1.708 0.505 - 187.1 1 2 0 -0.001 9 0 0 0 1.71E+07 1.86E+07 - - - 4.3193 0.9994 221125_WJC_METTL3_EV_vs_WT_F04.12302.12302.3 0.022 13/40 K.LSLTGHISTVR.G "sp|O43660|PLRG1_HUMAN,tr|H0YA24|H0YA24_HUMAN" 2 1182.6721 0.12 46575 12302 3 1182.66903 395.2313 Pleiotropic regulator 1 OS=Homo sapiens OX=9606 GN=PLRG1 PE=1 SV=1 9.76 2420.7 - 797790 - - - -2.5713 - 2.269 0.323 - 155.9 1 2 0 -0.003 11 0 0 0 8.63E+06 7.36E+07 - - - 4.4679 0.9901 221125_WJC_METTL3_EV_vs_WT_F04.12303.12303.2 1.01 18-Jul K.NLQTVNVDEN.- sp|P62899|RL31_HUMAN 1 1144.536 - 46576 12303 2 1144.536244 573.2753 60S ribosomal protein L31 OS=Homo sapiens OX=9606 GN=RPL31 PE=1 SV=1 3.67 2420.9 - 659987 - - - 0.1861 - 1.238 0.136 - 130 1 2 0 0.0002 10 0 0 0 - - - - - 0.6414 0.9993 221125_WJC_METTL3_EV_vs_WT_F04.12305.12305.2 0.000832 20-Dec K.ADAEAEC[160.03]NILR[166.11].K sp|Q96ES7|SGF29_HUMAN 1 1270.5851 1.47 46578 12305 2 1270.589603 636.2998 SAGA-associated factor 29 OS=Homo sapiens OX=9606 GN=SGF29 PE=1 SV=1 4.14 2421.1 - 441622 - - - 3.5275 - 2.692 0.46 - 791.5 1 2 0 0.0045 11 0 0 0 1.24E+07 8.41E+06 - - - 5.1161 1 221125_WJC_METTL3_EV_vs_WT_F04.12306.12306.2 3.30E-08 24-Dec K.VIQC[160.03]FAETGQVQK.L "sp|Q00610|CLH1_HUMAN,tr|A0A087WVQ6|A0A087WVQ6_HUMAN" 2 1506.7501 1.25 46579 12306 2 1506.751322 754.3823 Clathrin heavy chain 1 OS=Homo sapiens OX=9606 GN=CLTC PE=1 SV=5 5.97 2421.3 - 416737 - - - 0.8349 - 2.532 0.628 - 535.5 1 2 0 0.0013 13 0 0 0 7.09E+06 5.68E+06 - - - 6.0633 0.9998 221125_WJC_METTL3_EV_vs_WT_F04.12307.12307.2 0.000659 24-Dec R.AATMSAVEAATC[160.03]R[166.11].A "sp|Q53H96|P5CR3_HUMAN,tr|A0A0A0MQS1|A0A0A0MQS1_HUMAN,tr|B5MD87|B5MD87_HUMAN" 3 1347.615 0.46 46580 12307 2 1347.613018 674.8148 Pyrroline-5-carboxylate reductase 3 OS=Homo sapiens OX=9606 GN=PYCR3 PE=1 SV=3 6.04 2421.4 - 345595 - - - -1.5004 - 2.32 0.479 - 692.6 1 2 0 -0.002 13 0 0 0 5.04E+06 1.10E+07 - - - 4.7382 0.9998 221125_WJC_METTL3_EV_vs_WT_F04.12308.12308.3 5.52E-07 16/44 K.K[136.11]LNIGGGGLGYR[166.11].E "sp|Q86XP3|DDX42_HUMAN,tr|A0A0A0MSJ0|A0A0A0MSJ0_HUMAN" 2 1221.6949 1.2 46581 12308 3 1221.691028 408.2389 ATP-dependent RNA helicase DDX42 OS=Homo sapiens OX=9606 GN=DDX42 PE=1 SV=1 9.99 2421.5 - 268811 - - - -3.1497 - 3.128 0.382 - 263.1 1 2 0 -0.0038 12 0 0 0 9.54E+06 7.97E+06 - - - 5.9589 0.9999 221125_WJC_METTL3_EV_vs_WT_F04.12312.12312.3 0.000348 13/56 R.FGAPPHAGGGIGLER[166.11].V "sp|P14868|SYDC_HUMAN,tr|H7BZ35|H7BZ35_HUMAN" 2 1444.7451 1.04 46583 12312 3 1444.743033 482.589 "Aspartate--tRNA ligase, cytoplasmic OS=Homo sapiens OX=9606 GN=DARS1 PE=1 SV=2" 6.75 2422.1 - 1.76E+06 - - - -1.4079 - 2.537 0.438 - 125.7 1 2 0 -0.002 15 0 0 0 5.54E+07 5.35E+07 - - - 5.852 0.9989 221125_WJC_METTL3_EV_vs_WT_F04.12313.12313.3 0.0118 Dec-52 K.VMPAPPPKENAWVK.R "sp|P23588|IF4B_HUMAN,tr|E7EX17|E7EX17_HUMAN" 2 1562.8279 4.36 46584 12313 3 1562.828223 521.9499 Eukaryotic translation initiation factor 4B OS=Homo sapiens OX=9606 GN=EIF4B PE=1 SV=2 8.56 2422.1 - 1.21E+06 - - - 0.1939 - 2.294 0.327 - 189.5 1 2 1 0.0003 14 0 0 0 3.87E+07 8.89E+06 - - - 4.3922 0.9976 221125_WJC_METTL3_EV_vs_WT_F04.12314.12314.2 1.87E-05 13/24 R.GEGGILINSQGER[166.11].F "sp|P31040|SDHA_HUMAN,tr|A0A087X1I3|A0A087X1I3_HUMAN,tr|D6RFM5|D6RFM5_HUMAN,tr|A0A494C1T6|A0A494C1T6_HUMAN" 4 1338.6767 0.41 46585 12314 2 1338.671551 670.3456 "Succinate dehydrogenase [ubiquinone] flavoprotein subunit, mitochondrial OS=Homo sapiens OX=9606 GN=SDHA PE=1 SV=2" 4.53 2422.2 - 2.00E+06 - - - -3.8553 - 2.737 0.269 - 563.6 1 2 0 -0.0052 13 0 0 0 1.18E+07 2.89E+07 - - - 3.6104 0.9999 221125_WJC_METTL3_EV_vs_WT_F04.12315.12315.3 0.000191 Dec-44 R.TFLAVKPDGVQR.R "sp|Q13232|NDK3_HUMAN,tr|H3BRA8|H3BRA8_HUMAN,tr|H3BMQ7|H3BMQ7_HUMAN,tr|H3BPD9|H3BPD9_HUMAN" 4 1329.7405 1.21 46586 12315 3 1329.738966 444.2541 Nucleoside diphosphate kinase 3 OS=Homo sapiens OX=9606 GN=NME3 PE=1 SV=2 8.41 2422.3 - 1.18E+06 - - - -1.1423 - 1.99 0.401 - 159.4 1 2 0 -0.0015 12 0 0 0 6.09E+07 5.05E+07 - - - 4.9177 1 221125_WJC_METTL3_EV_vs_WT_F04.12319.12319.3 7.24E-06 13/48 R.ILSK[136.11]PIEVQVGGR[166.11].S "sp|Q7L014|DDX46_HUMAN,tr|A0A0C4DG89|A0A0C4DG89_HUMAN" 2 1412.847 1.88 46590 12319 3 1412.846037 471.9563 Probable ATP-dependent RNA helicase DDX46 OS=Homo sapiens OX=9606 GN=DDX46 PE=1 SV=2 8.75 2422.8 - 501409 - - - -0.6951 - 2.386 0.527 - 264.6 1 2 0 -0.001 13 0 0 0 1.93E+07 1.03E+07 - - - 6.773 0.9997 221125_WJC_METTL3_EV_vs_WT_F04.12323.12323.2 0.00475 20-Sep K.LFEEPEDPSNR[166.11].S "sp|P63151|2ABA_HUMAN,sp|Q9Y2T4|2ABG_HUMAN,tr|A0A590UJJ1|A0A590UJJ1_HUMAN,tr|E5RFR9|E5RFR9_HUMAN,tr|A0A590UJY3|A0A590UJY3_HUMAN" 5 1341.6076 0.63 46592 12323 2 1341.605884 671.8111 Serine\threonine-protein phosphatase 2A 55 kDa regulatory subunit B alpha isoform OS=Homo sapiens OX=9606 GN=PPP2R2A PE=1 SV=1 4 2423.3 - 2.12E+06 - - - -1.3014 - 1.851 0.418 - 249.4 1 2 0 -0.0017 11 0 0 0 3.53E+07 5.62E+07 - - - 3.7935 0.9998 221125_WJC_METTL3_EV_vs_WT_F04.12324.12324.2 0.000489 20-Dec K.LFEEPEDPSNR.S "sp|P63151|2ABA_HUMAN,sp|Q9Y2T4|2ABG_HUMAN,tr|A0A590UJJ1|A0A590UJJ1_HUMAN,tr|E5RFR9|E5RFR9_HUMAN,tr|A0A590UJY3|A0A590UJY3_HUMAN" 5 1331.5994 0.63 46593 12324 2 1331.597441 666.807 Serine\threonine-protein phosphatase 2A 55 kDa regulatory subunit B alpha isoform OS=Homo sapiens OX=9606 GN=PPP2R2A PE=1 SV=1 4 2423.4 - 1.63E+06 - - - -1.4411 - 2.183 0.529 - 470.1 1 2 0 -0.0019 11 0 0 0 3.53E+07 5.63E+07 - - - 5.0596 0.9998 221125_WJC_METTL3_EV_vs_WT_F04.12325.12325.2 0.00739 14-Dec R.K[136.11]VDWLTEK[136.11].M "sp|Q14240|IF4A2_HUMAN,sp|P38919|IF4A3_HUMAN,sp|P60842|IF4A1_HUMAN,tr|J3QL52|J3QL52_HUMAN,tr|J3KT12|J3KT12_HUMAN,tr|J3QS69|J3QS69_HUMAN,tr|I3L3H2|I3L3H2_HUMAN,tr|J3QL43|J3QL43_HUMAN,tr|J3KTN0|J3KTN0_HUMAN,tr|E7EQG2|E7EQG2_HUMAN,tr|J3KSZ0|J3KSZ0_HUMAN" 11 1033.5779 1.44 46594 12325 2 1033.576577 517.7962 Eukaryotic initiation factor 4A-II OS=Homo sapiens OX=9606 GN=EIF4A2 PE=1 SV=2 6.07 2423.5 - 1.16E+06 - - - -1.2761 - 2.111 0.396 - 510.1 1 2 0 -0.0013 8 0 0 0 7.38E+07 5.12E+07 - - - 4.2188 0.9947 221125_WJC_METTL3_EV_vs_WT_F04.12326.12326.2 0.0392 14-Sep K.QEIQHLFR.E "sp|P04844|RPN2_HUMAN,tr|H0Y5M1|H0Y5M1_HUMAN" 2 1069.5669 0.74 46595 12326 2 1069.571076 535.7907 Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit 2 OS=Homo sapiens OX=9606 GN=RPN2 PE=1 SV=3 6.75 2423.7 - 571749 - - - 3.925 - 1.63 0.319 - 385.2 1 2 0 0.0042 8 0 0 0 3.98E+06 5.36E+06 - - - 2.8694 0.9923 221125_WJC_METTL3_EV_vs_WT_F04.12327.12327.2 0.0025 20-Sep K.ADFQYQESQMR[166.11].A "sp|Q8TAV0|FA76A_HUMAN,tr|E9PQL1|E9PQL1_HUMAN,tr|B1AJQ5|B1AJQ5_HUMAN" 3 1411.6066 0.58 46596 12327 2 1411.607315 706.8106 Protein FAM76A OS=Homo sapiens OX=9606 GN=FAM76A PE=2 SV=1 4.37 2423.8 - 259239 - - - 0.5178 - 1.395 0.125 - 106.8 1 2 0 0.0007 11 0 0 0 2.59E+06 4.50E+06 - - - 0.8646 0.9978 221125_WJC_METTL3_EV_vs_WT_F04.12331.12331.3 0.0017 Sep-48 K.ITESVAETAQTIK.K sp|Q96A49|SYAP1_HUMAN 1 1389.7351 1.39 46598 12331 3 1389.733078 464.2523 Synapse-associated protein 1 OS=Homo sapiens OX=9606 GN=SYAP1 PE=1 SV=1 4.53 2424.2 - 3.40E+06 - - - -1.4729 - 2.125 0.211 - 166.1 1 2 0 -0.002 13 0 0 0 2.44E+08 1.76E+08 - - - 2.9356 1 221125_WJC_METTL3_EV_vs_WT_F04.12332.12332.3 0.000913 15/44 R.TFLAVK[136.11]PDGVQR[166.11].R "sp|Q13232|NDK3_HUMAN,tr|H3BRA8|H3BRA8_HUMAN,tr|H3BMQ7|H3BMQ7_HUMAN,tr|H3BPD9|H3BPD9_HUMAN" 4 1347.763 1.21 46599 12332 3 1347.763212 450.2616 Nucleoside diphosphate kinase 3 OS=Homo sapiens OX=9606 GN=NME3 PE=1 SV=2 8.41 2424.3 - 2.37E+06 - - - 0.1907 - 2.406 0.513 - 268.5 1 2 0 0.0003 12 0 0 0 6.03E+07 5.00E+07 - - - 6.693 0.9997 221125_WJC_METTL3_EV_vs_WT_F04.12333.12333.2 0.0022 14-Dec R.KVDWLTEK.M "sp|Q14240|IF4A2_HUMAN,sp|P38919|IF4A3_HUMAN,sp|P60842|IF4A1_HUMAN,tr|J3QL52|J3QL52_HUMAN,tr|J3KT12|J3KT12_HUMAN,tr|J3QS69|J3QS69_HUMAN,tr|I3L3H2|I3L3H2_HUMAN,tr|J3QL43|J3QL43_HUMAN,tr|J3KTN0|J3KTN0_HUMAN,tr|E7EQG2|E7EQG2_HUMAN,tr|J3KSZ0|J3KSZ0_HUMAN" 11 1017.5495 1.44 46600 12333 2 1017.548348 509.782 Eukaryotic initiation factor 4A-II OS=Homo sapiens OX=9606 GN=EIF4A2 PE=1 SV=2 6.07 2424.4 - 1.75E+06 - - - -1.1282 - 2.122 0.376 - 587.6 1 2 0 -0.0011 8 0 0 0 7.38E+07 5.12E+07 - - - 4.0869 0.9996 221125_WJC_METTL3_EV_vs_WT_F04.12338.12338.2 0.000984 24-Dec K.LAQAEEQLEQETR[166.11].E "sp|Q7Z406|MYH14_HUMAN,tr|A1L2Z2|A1L2Z2_HUMAN" 2 1553.7561 1.46 46605 12338 2 1553.752912 777.8853 Myosin-14 OS=Homo sapiens OX=9606 GN=MYH14 PE=1 SV=2 4.09 2425 - 369498 - - - -2.0421 - 2.288 0.399 - 499.3 1 2 0 -0.0032 13 0 0 0 6.12E+06 4.20E+06 - - - 4.1113 0.9999 221125_WJC_METTL3_EV_vs_WT_F04.12341.12341.2 1.70E-06 20-Oct K.LTDNGTEFSVK.V "sp|P52732|KIF11_HUMAN,tr|A0A7I2YQY4|A0A7I2YQY4_HUMAN,tr|A0A7I2V3A9|A0A7I2V3A9_HUMAN,tr|A0A7I2V3V3|A0A7I2V3V3_HUMAN" 4 1209.5877 5.61 46606 12341 2 1209.587584 605.8011 Kinesin-like protein KIF11 OS=Homo sapiens OX=9606 GN=KIF11 PE=1 SV=2 4.37 2425.4 - 7.59E+06 - - - -0.1232 - 2.149 0.582 - 261.2 1 2 0 -0.0001 11 0 0 0 3.22E+08 5.74E+07 - - - 5.4091 0.9994 221125_WJC_METTL3_EV_vs_WT_F04.12342.12342.2 3.47E-05 20-Aug R.C[160.03]TPAC[160.03]ISLGSR[166.11].T "sp|O95757|HS74L_HUMAN,tr|D6RJ96|D6RJ96_HUMAN" 2 1230.5724 0.001 46607 12342 2 1230.569282 616.2935 Heat shock 70 kDa protein 4L OS=Homo sapiens OX=9606 GN=HSPA4L PE=1 SV=3 8.07 2425.4 - 1.89E+06 - - - -2.5728 - 1.615 0.509 - 185.5 1 2 0 -0.0032 11 0 0 0 0.00E+00 2.01E+07 - - - 4.0962 0.9998 221125_WJC_METTL3_EV_vs_WT_F04.12343.12343.3 0.000258 14/36 K.AQLEALELKK.T "sp|P42694|HELZ_HUMAN,tr|J3QS41|J3QS41_HUMAN" 2 1141.6707 2.07 46608 12343 3 1141.668418 381.5642 Probable helicase with zinc finger domain OS=Homo sapiens OX=9606 GN=HELZ PE=1 SV=2 6.19 2425.6 - 1.30E+06 - - - -1.9761 - 2.397 0.353 - 241.3 1 2 0 -0.0023 10 0 0 0 2.15E+07 1.04E+07 - - - 5.0281 0.9999 221125_WJC_METTL3_EV_vs_WT_F04.12345.12345.2 1.31E-05 16-Oct R.DGYDYDGYR.L "sp|Q07955|SRSF1_HUMAN,tr|J3KTL2|J3KTL2_HUMAN" 2 1122.4254 1.19 46610 12345 2 1122.424645 562.22 Serine\arginine-rich splicing factor 1 OS=Homo sapiens OX=9606 GN=SRSF1 PE=1 SV=2 3.93 2425.8 - 837109 - - - -0.6887 - 1.679 0.597 - 223.2 1 2 0 -0.0008 9 0 0 0 3.61E+07 3.02E+07 - - - 4.9494 0.9811 221125_WJC_METTL3_EV_vs_WT_F04.12348.12348.3 3.02E-05 16/56 K.SLGPLHAAAAAAAPR[166.11].R sp|Q9H2Z4|NKX24_HUMAN 1 1382.7658 1.39 46613 12348 3 1382.756296 461.9292 Homeobox protein Nkx-2.4 OS=Homo sapiens OX=9606 GN=NKX2-4 PE=1 SV=3 9.49 2426.2 - 679042 - - - -6.8746 - 2.256 0.313 - 249.9 1 2 0 -0.0095 15 0 0 0 1.52E+07 1.09E+07 - - - 4.15 0.9948 221125_WJC_METTL3_EV_vs_WT_F04.12349.12349.3 0.0336 Nov-32 K.MVDQLFC[160.03]KK.F "sp|P78347|GTF2I_HUMAN,tr|A0A494C0Q7|A0A494C0Q7_HUMAN,tr|A0A494C1K3|A0A494C1K3_HUMAN" 3 1167.578 0.66 46614 12349 3 1167.574749 390.2 General transcription factor II-I OS=Homo sapiens OX=9606 GN=GTF2I PE=1 SV=2 7.95 2426.3 - 642517 - - - -2.8152 - 1.902 0.225 - 126.8 1 2 0 -0.0033 9 0 0 0 2.45E+07 3.72E+07 - - - 2.9852 1 221125_WJC_METTL3_EV_vs_WT_F04.12353.12353.3 4.85E-08 16/56 R.FGAPPHAGGGIGLER.V "sp|P14868|SYDC_HUMAN,tr|H7BZ35|H7BZ35_HUMAN" 2 1434.7368 0.92 46617 12353 3 1434.735409 479.2529 "Aspartate--tRNA ligase, cytoplasmic OS=Homo sapiens OX=9606 GN=DARS1 PE=1 SV=2" 6.75 2426.8 - 2.27E+06 - - - -0.9674 - 3.224 0.575 - 221.3 1 2 0 -0.0014 15 0 0 0 4.26E+07 4.63E+07 - - - 8.0049 0.9395 221125_WJC_METTL3_EV_vs_WT_F04.12356.12356.2 0.00288 22-Oct R.MSGEC[160.03]APNVSVS.V sp|P04264|K2C1_HUMAN 1 1236.5115 - 46619 12356 2 1236.508954 619.263 "Keratin, type II cytoskeletal 1 OS=Homo sapiens OX=9606 GN=KRT1 PE=1 SV=6" 4 2427.1 - 1.68E+06 - - - -2.0372 - 1.415 0.42 - 215 1 1 0 -0.0025 12 0 0 0 - - - - - 3.0557 0.9999 221125_WJC_METTL3_EV_vs_WT_F04.12359.12359.2 0.000224 16-Oct R.DGYDYDGYR[166.11].L "sp|Q07955|SRSF1_HUMAN,tr|J3KTL2|J3KTL2_HUMAN" 2 1132.4337 1.19 46622 12359 2 1132.433721 567.2241 Serine\arginine-rich splicing factor 1 OS=Homo sapiens OX=9606 GN=SRSF1 PE=1 SV=2 3.93 2427.5 - 1.25E+06 - - - 0.0291 - 1.728 0.55 - 251.6 1 2 0 0 9 0 0 0 3.61E+07 3.02E+07 - - - 4.6857 0.9501 221125_WJC_METTL3_EV_vs_WT_F04.12362.12362.3 1.55 Sep-40 R.GPAHC[160.03]LLLGER.V sp|Q15274|NADC_HUMAN 1 1221.6288 1.5 46625 12362 3 1221.626159 408.2169 Nicotinate-nucleotide pyrophosphorylase [carboxylating] OS=Homo sapiens OX=9606 GN=QPRT PE=1 SV=3 6.74 2427.9 - 362005 - - - -2.1832 - 1.681 0.112 - 80.7 1 2 0 -0.0027 11 0 0 0 7.49E+06 5.00E+06 - - - 1.2634 0.9999 221125_WJC_METTL3_EV_vs_WT_F04.12363.12363.2 1.24E-06 13/20 K.KMVTPYANGWK.L "sp|O43251|RFOX2_HUMAN,tr|B0QYV1|B0QYV1_HUMAN,tr|B0QYY4|B0QYY4_HUMAN,tr|S4R469|S4R469_HUMAN,tr|A0A0G2JRD1|A0A0G2JRD1_HUMAN,tr|A0A0G2JRA5|A0A0G2JRA5_HUMAN,tr|S4R3K7|S4R3K7_HUMAN" 7 1293.654 4.01 46626 12363 2 1293.653277 647.8343 RNA binding protein fox-1 homolog 2 OS=Homo sapiens OX=9606 GN=RBFOX2 PE=1 SV=3 9.7 2428 - 303213 - - - -0.5419 - 2.386 0.542 - 546.3 1 2 0 -0.0007 11 0 0 0 9.24E+06 2.31E+06 - - - 5.3965 0.9999 221125_WJC_METTL3_EV_vs_WT_F04.12367.12367.3 4.88E-06 13/40 K.KMVTPYANGWK.L "sp|O43251|RFOX2_HUMAN,tr|B0QYV1|B0QYV1_HUMAN,tr|B0QYY4|B0QYY4_HUMAN,tr|S4R469|S4R469_HUMAN,tr|A0A0G2JRD1|A0A0G2JRD1_HUMAN,tr|A0A0G2JRA5|A0A0G2JRA5_HUMAN,tr|S4R3K7|S4R3K7_HUMAN" 7 1293.654 1.28 46628 12367 3 1293.65257 432.2253 RNA binding protein fox-1 homolog 2 OS=Homo sapiens OX=9606 GN=RBFOX2 PE=1 SV=3 9.7 2428.5 - 1.32E+06 - - - -1.0884 - 2.186 0.459 - 251.9 1 2 0 -0.0014 11 0 0 0 2.76E+07 2.16E+07 - - - 5.8787 1 221125_WJC_METTL3_EV_vs_WT_F04.12369.12369.3 1.11E-06 15/40 K.K[136.11]MVTPYANGWK[136.11].L "sp|O43251|RFOX2_HUMAN,tr|B0QYV1|B0QYV1_HUMAN,tr|B0QYY4|B0QYY4_HUMAN,tr|S4R469|S4R469_HUMAN,tr|A0A0G2JRD1|A0A0G2JRD1_HUMAN,tr|A0A0G2JRA5|A0A0G2JRA5_HUMAN,tr|S4R3K7|S4R3K7_HUMAN" 7 1309.6824 1.3 46630 12369 3 1309.681871 437.5681 RNA binding protein fox-1 homolog 2 OS=Homo sapiens OX=9606 GN=RBFOX2 PE=1 SV=3 9.7 2428.8 - 1.00E+06 - - - -0.3871 - 2.633 0.548 - 350.2 1 2 0 -0.0005 11 0 0 0 2.74E+07 2.11E+07 - - - 7.3998 0.9902 221125_WJC_METTL3_EV_vs_WT_F04.12370.12370.2 0.343 16-Aug K.AEEEFNIEK.G "sp|P36543|VATE1_HUMAN,sp|Q96A05|VATE2_HUMAN,tr|C9J8H1|C9J8H1_HUMAN" 3 1107.5084 1.45 46631 12370 2 1107.507681 554.7615 V-type proton ATPase subunit E 1 OS=Homo sapiens OX=9606 GN=ATP6V1E1 PE=1 SV=1 4.09 2428.9 - 999357 - - - -0.6673 - 1.063 0.198 - 158.5 1 2 0 -0.0007 9 0 0 0 8.67E+06 5.97E+06 - - - 0.6799 0.9998 221125_WJC_METTL3_EV_vs_WT_F04.12373.12373.2 0.413 22-Nov R.QVQLQQEAEPLK[136.11].Q "sp|Q9ULV3|CIZ1_HUMAN,tr|Q5SYW2|Q5SYW2_HUMAN,tr|F5H2X7|F5H2X7_HUMAN,tr|H0Y5D5|H0Y5D5_HUMAN,tr|Q9BTG3|Q9BTG3_HUMAN" 5 1417.7656 2.9 46634 12373 2 1417.765621 709.8901 Cip1-interacting zinc finger protein OS=Homo sapiens OX=9606 GN=CIZ1 PE=1 SV=2 4.53 2429.3 - 362576 - - - -0.0162 - 2.294 0.39 - 434.1 1 2 0 0 12 0 0 0 8.88E+07 3.06E+07 - - - 4.1062 0.9998 221125_WJC_METTL3_EV_vs_WT_F04.12375.12375.2 4.53E-07 13/24 K.ITESVAETAQTIK.K sp|Q96A49|SYAP1_HUMAN 1 1389.7351 1.27 46635 12375 2 1389.737553 695.8748 Synapse-associated protein 1 OS=Homo sapiens OX=9606 GN=SYAP1 PE=1 SV=1 4.53 2429.5 - 1.39E+06 - - - 1.7471 - 2.671 0.536 - 581.7 1 2 0 0.0024 13 0 0 0 1.64E+09 1.29E+09 - - - 5.5206 0.9999 221125_WJC_METTL3_EV_vs_WT_F04.12377.12377.2 0.00197 16-Sep K.GSDFDC[160.03]ELR[166.11].L "sp|P61978|HNRPK_HUMAN,tr|Q5T6W2|Q5T6W2_HUMAN" 2 1107.453 1.2 46636 12377 2 1107.452032 554.7338 Heterogeneous nuclear ribonucleoprotein K OS=Homo sapiens OX=9606 GN=HNRNPK PE=1 SV=1 4.03 2429.7 - 2.33E+06 - - - -0.9138 - 1.938 0.535 - 463.2 1 2 0 -0.001 9 0 0 0 1.23E+08 1.02E+08 - - - 4.9064 0.9998 221125_WJC_METTL3_EV_vs_WT_F04.12378.12378.2 0.00164 16-Sep K.GSDFDC[160.03]ELR.L "sp|P61978|HNRPK_HUMAN,tr|Q5T6W2|Q5T6W2_HUMAN" 2 1097.4448 1.2 46637 12378 2 1097.443392 549.7297 Heterogeneous nuclear ribonucleoprotein K OS=Homo sapiens OX=9606 GN=HNRNPK PE=1 SV=1 4.03 2429.8 - 2.01E+06 - - - -1.2593 - 1.972 0.528 - 515.8 1 2 0 -0.0014 9 0 0 0 1.23E+08 1.02E+08 - - - 4.9049 0.9996 221125_WJC_METTL3_EV_vs_WT_F04.12379.12379.2 4.67E-05 15/22 R.QVQLQQEAEPLK.Q "sp|Q9ULV3|CIZ1_HUMAN,tr|Q5SYW2|Q5SYW2_HUMAN,tr|F5H2X7|F5H2X7_HUMAN,tr|H0Y5D5|H0Y5D5_HUMAN,tr|Q9BTG3|Q9BTG3_HUMAN" 5 1409.7514 2.9 46638 12379 2 1409.755468 705.883 Cip1-interacting zinc finger protein OS=Homo sapiens OX=9606 GN=CIZ1 PE=1 SV=2 4.53 2429.8 - 1.61E+06 - - - 2.8544 - 2.58 0.498 - 520.2 1 2 0 0.004 12 0 0 0 8.88E+07 3.06E+07 - - - 5.2118 0.9997 221125_WJC_METTL3_EV_vs_WT_F04.12383.12383.2 2.48E-05 24-Dec R.QDPQSTAAATVLK[136.11].R "sp|Q8WV92|MITD1_HUMAN,tr|F8WED5|F8WED5_HUMAN,tr|B8ZZL5|B8ZZL5_HUMAN,tr|A0A1W2PP14|A0A1W2PP14_HUMAN" 4 1336.7078 1.23 46642 12383 2 1336.710417 669.3612 MIT domain-containing protein 1 OS=Homo sapiens OX=9606 GN=MITD1 PE=1 SV=1 5.84 2430.3 - 635356 - - - 1.9615 - 2.327 0.465 - 476.1 1 2 0 0.0026 13 0 0 0 2.50E+07 2.03E+07 - - - 4.6423 0.9999 221125_WJC_METTL3_EV_vs_WT_F04.12384.12384.3 1.35E-05 Dec-48 R.ILSKPIEVQVGGR.S "sp|Q7L014|DDX46_HUMAN,tr|A0A0C4DG89|A0A0C4DG89_HUMAN" 2 1394.8245 1.88 46643 12384 3 1394.825943 465.9488 Probable ATP-dependent RNA helicase DDX46 OS=Homo sapiens OX=9606 GN=DDX46 PE=1 SV=2 8.75 2430.4 - 589226 - - - 0.9994 - 2.211 0.456 - 165.2 1 2 0 0.0014 13 0 0 0 1.93E+07 1.03E+07 - - - 5.7748 0.9996 221125_WJC_METTL3_EV_vs_WT_F04.12385.12385.3 0.00337 Sep-36 K.AQLEALELK[136.11]K[136.11].T "sp|P42694|HELZ_HUMAN,tr|J3QS41|J3QS41_HUMAN" 2 1157.6991 2.07 46644 12385 3 1157.697322 386.907 Probable helicase with zinc finger domain OS=Homo sapiens OX=9606 GN=HELZ PE=1 SV=2 6.19 2430.6 - 582179 - - - -1.5133 - 1.797 0.367 - 79.8 2 2 0 -0.0018 10 0 0 0 2.15E+07 1.04E+07 - - - 4.2036 0.9852 221125_WJC_METTL3_EV_vs_WT_F04.12386.12386.3 0.0608 Jul-52 K.FLETESHPSIPPPK.L "sp|Q15643|TRIPB_HUMAN,tr|H0YJ97|H0YJ97_HUMAN" 2 1577.809 2.08 46645 12386 3 1577.808747 526.9436 Thyroid receptor-interacting protein 11 OS=Homo sapiens OX=9606 GN=TRIP11 PE=1 SV=3 5.4 2430.7 - 341930 - - - -0.1344 - 1.248 0.219 - 40 1 2 0 -0.0002 14 0 0 0 5.93E+06 2.86E+06 - - - 1.5703 0.9998 221125_WJC_METTL3_EV_vs_WT_F04.12390.12390.3 0.024 15/36 K.QIFLGGVDK[136.11]R[166.11].T sp|P05141|ADT2_HUMAN 1 1149.6625 0.001 46648 12390 3 1149.660787 384.2281 ADP\ATP translocase 2 OS=Homo sapiens OX=9606 GN=SLC25A5 PE=1 SV=7 8.75 2431.2 - 2.85E+06 - - - -1.5013 - 2.277 0.349 - 404 1 2 0 -0.0017 10 0 0 0 0.00E+00 4.61E+07 - - - 4.8336 0.9999 221125_WJC_METTL3_EV_vs_WT_F04.12393.12393.3 0.000647 Dec-32 K.MVDQLFC[160.03]K[136.11]K[136.11].F "sp|P78347|GTF2I_HUMAN,tr|A0A494C0Q7|A0A494C0Q7_HUMAN,tr|A0A494C1K3|A0A494C1K3_HUMAN" 3 1183.6064 0.66 46651 12393 3 1183.605547 395.5428 General transcription factor II-I OS=Homo sapiens OX=9606 GN=GTF2I PE=1 SV=2 7.95 2431.4 - 1.68E+06 - - - -0.7511 - 2.117 0.424 - 249.9 1 2 0 -0.0009 9 0 0 0 2.45E+07 3.70E+07 - - - 5.5273 0.9987 221125_WJC_METTL3_EV_vs_WT_F04.12394.12394.2 0.522 18-Nov K.ISDIQSQLEK[136.11].L sp|Q9NVP1|DDX18_HUMAN 1 1167.6227 0.53 46652 12394 2 1167.623298 584.8186 ATP-dependent RNA helicase DDX18 OS=Homo sapiens OX=9606 GN=DDX18 PE=1 SV=2 4.37 2431.5 - 769653 - - - 0.5396 - 2.086 0.154 - 261.5 1 2 0 0.0006 10 0 0 0 9.26E+06 1.75E+07 - - - 2.2305 0.8435 221125_WJC_METTL3_EV_vs_WT_F04.12395.12395.2 10.6 16-Aug R.NMSYQGFTK[136.11].D "sp|Q9P2J5|SYLC_HUMAN,tr|A0A6I8PIV1|A0A6I8PIV1_HUMAN,tr|A0A6I8PRS0|A0A6I8PRS0_HUMAN,tr|A0A6I8PLB8|A0A6I8PLB8_HUMAN,tr|A0A6I8PIP7|A0A6I8PIP7_HUMAN,tr|A0A6I8PIT3|A0A6I8PIT3_HUMAN,tr|A0A6I8PTV8|A0A6I8PTV8_HUMAN,tr|A0A6I8PRU9|A0A6I8PRU9_HUMAN,tr|A0A6I8PS05|A0A6I8PS05_HUMAN,tr|B4DER1|B4DER1_HUMAN,tr|A0A6I8PL42|A0A6I8PL42_HUMAN" 11 1082.4946 0.69 46653 12395 2 1082.497896 542.2546 "Leucine--tRNA ligase, cytoplasmic OS=Homo sapiens OX=9606 GN=LARS1 PE=1 SV=2" 8.59 2431.6 - 656418 - - - 3.0162 - 1.058 0.072 - 247.5 1 2 0 0.0033 9 0 0 0 6.19E+06 8.94E+06 - - - -0.2651 0.9989 221125_WJC_METTL3_EV_vs_WT_F04.12396.12396.2 0.255 20-Oct K.LVLVGDGGTGK[136.11].T "sp|P62826|RAN_HUMAN,tr|H0YFC6|H0YFC6_HUMAN,tr|B5MDF5|B5MDF5_HUMAN,tr|J3KQE5|J3KQE5_HUMAN,tr|F5H018|F5H018_HUMAN" 5 1022.5852 1.75 46654 12396 2 1022.583989 512.2999 GTP-binding nuclear protein Ran OS=Homo sapiens OX=9606 GN=RAN PE=1 SV=3 5.84 2431.7 - 329649 - - - -1.1451 - 1.933 0.231 - 234.6 1 2 0 -0.0012 11 0 0 0 6.68E+06 3.81E+06 - - - 2.5297 0.9131 221125_WJC_METTL3_EV_vs_WT_F04.12403.12403.3 4.50E-05 Sep-40 Y.YVTIIDAPGHR.D "sp|P68104|EF1A1_HUMAN,sp|Q5VTE0|EF1A3_HUMAN,tr|A0A7I2V659|A0A7I2V659_HUMAN,tr|A0A7I2V3H3|A0A7I2V3H3_HUMAN,tr|Q5JR01|Q5JR01_HUMAN,tr|A0A7I2V5N4|A0A7I2V5N4_HUMAN,tr|A0A087WVQ9|A0A087WVQ9_HUMAN,tr|A6PW80|A6PW80_HUMAN,tr|A0A087WV01|A0A087WV01_HUMAN" 9 1240.6564 0.17 46659 12403 3 1240.651926 414.5594 Elongation factor 1-alpha 1 OS=Homo sapiens OX=9606 GN=EEF1A1 PE=1 SV=1 6.74 2432.6 - 474445 - - - -3.6231 - 1.757 0.418 - 94.6 1 1 0 -0.0045 11 0 0 0 7.78E+06 4.65E+07 - - - 4.8002 0.9997 221125_WJC_METTL3_EV_vs_WT_F04.12406.12406.3 2.68E-07 15/44 K.IPEVPLHDTPER[166.11].S sp|Q96AY2|EME1_HUMAN 1 1411.7335 1.96 46662 12406 3 1411.733208 471.5851 Crossover junction endonuclease EME1 OS=Homo sapiens OX=9606 GN=EME1 PE=1 SV=2 4.65 2433 - 427869 - - - -0.2061 - 2.69 0.269 - 395.4 1 2 0 -0.0003 12 0 0 0 1.14E+07 5.80E+06 - - - 4.2819 0.9363 221125_WJC_METTL3_EV_vs_WT_F04.12407.12407.2 0.0236 18-Jul K.NEAITSFEGK[136.11].T "sp|Q96T51|RUFY1_HUMAN,tr|H0YA47|H0YA47_HUMAN" 2 1102.5386 3.15 46663 12407 2 1102.531019 552.2766 RUN and FYVE domain-containing protein 1 OS=Homo sapiens OX=9606 GN=RUFY1 PE=1 SV=2 4.53 2433.1 - 424142 - - - -6.8796 - 1.602 0.277 - 173.7 1 2 0 -0.0076 10 0 0 0 5.11E+06 1.62E+06 - - - 2.4 0.9876 221125_WJC_METTL3_EV_vs_WT_F04.12409.12409.3 0.15 Dec-44 K.LKQSLPPGLAVK.E sp|P63173|RL38_HUMAN 1 1249.7758 1.09 46664 12409 3 1249.775298 417.5992 60S ribosomal protein L38 OS=Homo sapiens OX=9606 GN=RPL38 PE=1 SV=2 10 2433.3 - 6.26E+06 - - - -0.4081 - 1.938 0.202 - 247.8 1 2 1 -0.0005 12 0 0 0 1.85E+08 1.70E+08 - - - 2.626 0.9999 221125_WJC_METTL3_EV_vs_WT_F04.12410.12410.2 3.58E-05 22-Dec R.DYVAPTANLDQK.D sp|Q7KZF4|SND1_HUMAN 1 1333.6514 0.52 46665 12410 2 1333.652044 667.833 Staphylococcal nuclease domain-containing protein 1 OS=Homo sapiens OX=9606 GN=SND1 PE=1 SV=1 4.21 2433.4 - 825233 - - - 0.4866 - 2.196 0.527 - 419.3 1 2 0 0.0006 12 0 0 0 6.99E+06 1.34E+07 - - - 5.003 0.9716 221125_WJC_METTL3_EV_vs_WT_F04.12411.12411.3 0.51 Oct-44 K.LK[136.11]QSLPPGLAVK[136.11].E sp|P63173|RL38_HUMAN 1 1265.8042 1.09 46666 12411 3 1265.80369 422.942 60S ribosomal protein L38 OS=Homo sapiens OX=9606 GN=RPL38 PE=1 SV=2 10 2433.5 - 5.33E+06 - - - -0.4092 - 1.744 0.18 - 109.2 1 2 1 -0.0005 12 0 0 0 1.85E+08 1.70E+08 - - - 2.0883 0.9999 221125_WJC_METTL3_EV_vs_WT_F04.12412.12412.3 0.00018 14/40 K.SDLLGK[136.11]PLGPR[166.11].T "sp|Q8IY67|RAVR1_HUMAN,tr|E9PAU2|E9PAU2_HUMAN,tr|A0A087WZ13|A0A087WZ13_HUMAN" 3 1169.6887 0.92 46667 12412 3 1169.688098 390.9035 Ribonucleoprotein PTB-binding 1 OS=Homo sapiens OX=9606 GN=RAVER1 PE=1 SV=1 8.46 2433.5 - 2.16E+06 - - - -0.5386 - 2.417 0.432 - 281.9 1 2 0 -0.0006 11 0 0 0 2.29E+08 2.50E+08 - - - 5.8633 0.9998 221125_WJC_METTL3_EV_vs_WT_F04.12414.12414.2 2.80E-06 20-Nov R.WPTETDVSSAK[136.11].N "sp|P27816|MAP4_HUMAN,tr|E7EVA0|E7EVA0_HUMAN,tr|A0A804HKE7|A0A804HKE7_HUMAN" 3 1227.5863 0.001 46669 12414 2 1227.587996 614.8004 Microtubule-associated protein 4 OS=Homo sapiens OX=9606 GN=MAP4 PE=1 SV=3 4.37 2433.8 - 485409 - - - 1.3962 - 2.386 0.528 - 431.6 1 2 0 0.0017 11 0 0 0 0.00E+00 9.68E+06 - - - 5.2928 0.9987 221125_WJC_METTL3_EV_vs_WT_F04.12417.12417.2 0.00136 20-Sep R.NSSISGPFGSR[166.11].S "sp|Q13610|PWP1_HUMAN,tr|B4DJV5|B4DJV5_HUMAN" 2 1117.5392 1.01 46672 12417 2 1117.53607 559.7769 Periodic tryptophan protein 1 homolog OS=Homo sapiens OX=9606 GN=PWP1 PE=1 SV=1 9.75 2434.2 - 291154 - - - -2.7614 - 1.613 0.413 - 196.1 1 2 0 -0.0031 11 0 0 0 1.13E+07 1.12E+07 - - - 3.3838 1 221125_WJC_METTL3_EV_vs_WT_F04.12418.12418.3 3.79E-06 Dec-36 R.AFESDVFHNR[166.11].T "sp|O14545|TRAD1_HUMAN,tr|F8VNX8|F8VNX8_HUMAN" 2 1230.5657 0.31 46673 12418 3 1230.56447 411.1958 TRAF-type zinc finger domain-containing protein 1 OS=Homo sapiens OX=9606 GN=TRAFD1 PE=1 SV=1 5.32 2434.3 - 270829 - - - -1.0036 - 2.172 0.502 - 180.3 1 2 0 -0.0012 10 0 0 0 1.76E+06 5.74E+06 - - - 6.4017 0.9971 221125_WJC_METTL3_EV_vs_WT_F04.12419.12419.2 0.397 20-Nov K.IAAQLLQQEQK[136.11].N sp|Q5VUJ6|LRCH2_HUMAN 1 1276.7231 0.61 46674 12419 2 1276.720689 639.3688 Leucine-rich repeat and calponin homology domain-containing protein 2 OS=Homo sapiens OX=9606 GN=LRCH2 PE=1 SV=2 6 2434.5 - 245382 - - - -1.85 - 1.968 0.157 - 431.7 1 2 0 -0.0024 11 0 0 0 3.42E+06 5.60E+06 - - - 2.0314 0.9944 221125_WJC_METTL3_EV_vs_WT_F04.12421.12421.2 0.0328 22-Nov K.LK[136.11]QSLPPGLAVK[136.11].E sp|P63173|RL38_HUMAN 1 1265.8042 1.18 46675 12421 2 1265.80393 633.9094 60S ribosomal protein L38 OS=Homo sapiens OX=9606 GN=RPL38 PE=1 SV=2 10 2434.7 - 439132 - - - -0.2196 - 1.784 0.332 - 267.3 1 2 1 -0.0003 12 0 0 0 2.38E+07 2.03E+07 - - - 3.0161 0.999 221125_WJC_METTL3_EV_vs_WT_F04.12423.12423.2 0.0203 12-Jun R.DYSQYYR.T "sp|Q04695|K1C17_HUMAN,tr|K7EPJ9|K7EPJ9_HUMAN,tr|F5GWP8|F5GWP8_HUMAN" 3 993.4192 999 46676 12423 2 993.419347 497.7169 "Keratin, type I cytoskeletal 17 OS=Homo sapiens OX=9606 GN=KRT17 PE=1 SV=2" 5.83 2434.9 - 7.06E+06 - - - 0.1369 - 1.294 0.336 - 142.5 1 2 0 0.0001 7 0 0 0 2.88E+08 0.00E+00 - - - 2.3393 0.9999 221125_WJC_METTL3_EV_vs_WT_F04.12424.12424.2 0.00552 20-Nov R.DLIQDQNMDEK[136.11].G sp|Q9H307|PININ_HUMAN 1 1355.6118 1.63 46677 12424 2 1355.611657 678.8132 Pinin OS=Homo sapiens OX=9606 GN=PNN PE=1 SV=5 3.84 2435 - 1.83E+06 - - - -0.1387 - 2.292 0.504 - 399.4 1 2 0 -0.0002 11 0 0 0 5.21E+07 3.19E+07 - - - 5.0073 0.9998 221125_WJC_METTL3_EV_vs_WT_F04.12425.12425.3 0.0905 13/48 K.AGFPLAVHSGAAR.A sp|Q9BY49|PECR_HUMAN 1 1252.6677 1.45 46678 12425 3 1252.667642 418.5632 Peroxisomal trans-2-enoyl-CoA reductase OS=Homo sapiens OX=9606 GN=PECR PE=1 SV=2 9.8 2435 - 5.47E+06 - - - -0.0104 - 2.51 0.304 - 184.5 1 2 0 0 13 0 0 0 8.21E+07 5.66E+07 - - - 4.4245 0.9999 221125_WJC_METTL3_EV_vs_WT_F04.12426.12426.2 1.74E-06 18-Dec R.NSGLVSITSR.E sp|Q8WUM0|NU133_HUMAN 1 1032.5564 0.76 46679 12426 2 1032.557102 517.2855 Nuclear pore complex protein Nup133 OS=Homo sapiens OX=9606 GN=NUP133 PE=1 SV=2 9.75 2435.1 - 1.16E+06 - - - 0.706 - 2.381 0.522 - 750.3 1 2 0 0.0007 10 0 0 0 1.58E+07 2.07E+07 - - - 5.3178 0.9988 221125_WJC_METTL3_EV_vs_WT_F04.12427.12427.3 7.95E-05 Dec-44 K.MAFVNSVAKPPR.D "sp|Q14241|ELOA1_HUMAN,tr|A0A024RAC6|A0A024RAC6_HUMAN" 2 1315.7071 1.44 46680 12427 3 1315.702776 439.5763 Elongin-A OS=Homo sapiens OX=9606 GN=ELOA PE=1 SV=2 11 2435.2 - 1.06E+06 - - - -3.269 - 2.676 0.275 - 250.8 1 2 0 -0.0043 12 0 0 0 2.59E+07 1.79E+07 - - - 4.3332 0.9999 221125_WJC_METTL3_EV_vs_WT_F04.12430.12430.2 4.37E-06 13/20 R.QTVEADVNGLR.R sp|P08779|K1C16_HUMAN 1 1200.6099 1267.82 46683 12430 2 1200.61046 601.3122 "Keratin, type I cytoskeletal 16 OS=Homo sapiens OX=9606 GN=KRT16 PE=1 SV=4" 4.37 2435.4 - 881546 - - - 0.4956 - 2.506 0.488 - 945.5 1 2 0 0.0006 11 0 0 0 1.01E+09 8.00E+05 - - - 5.1304 0.9999 221125_WJC_METTL3_EV_vs_WT_F04.12431.12431.2 0.000201 14/22 K.IAEQVASFQEEK[136.11].S "sp|P35221|CTNA1_HUMAN,tr|G3XAM7|G3XAM7_HUMAN" 2 1385.6918 2.2 46684 12431 2 1385.691649 693.8532 Catenin alpha-1 OS=Homo sapiens OX=9606 GN=CTNNA1 PE=1 SV=1 4.25 2435.6 - 696900 - - - -0.1162 - 3.002 0.424 - 851.6 1 2 0 -0.0002 12 0 0 0 1.76E+07 7.97E+06 - - - 5.065 0.9997 221125_WJC_METTL3_EV_vs_WT_F04.12432.12432.2 5.10E-05 20-Oct K.YQAVTATLEEK[136.11].R "sp|P40429|RL13A_HUMAN,sp|Q6NVV1|R13P3_HUMAN,tr|M0QYS1|M0QYS1_HUMAN,tr|Q8J015|Q8J015_HUMAN,tr|A0A7I2V2L9|A0A7I2V2L9_HUMAN,tr|A0A7I2V5L3|A0A7I2V5L3_HUMAN" 6 1259.6489 0.96 46685 12432 2 1259.649287 630.8317 60S ribosomal protein L13a OS=Homo sapiens OX=9606 GN=RPL13A PE=1 SV=2 4.53 2435.7 - 690290 - - - 0.3207 - 1.964 0.376 - 242.7 1 2 0 0.0004 11 0 0 0 2.71E+07 2.83E+07 - - - 3.644 0.9757 221125_WJC_METTL3_EV_vs_WT_F04.12434.12434.2 5.02E-05 22-Sep A.YVNFQQPADAER.A "sp|Q13310|PABP4_HUMAN,sp|P11940|PABP1_HUMAN,tr|A0A7I2V649|A0A7I2V649_HUMAN,tr|B1ANR0|B1ANR0_HUMAN,tr|A0A7I2V4L7|A0A7I2V4L7_HUMAN,tr|E5RHG7|E5RHG7_HUMAN,tr|B1ANR1|B1ANR1_HUMAN,tr|H0YAR2|H0YAR2_HUMAN,tr|E7ERJ7|E7ERJ7_HUMAN,tr|E5RJB9|E5RJB9_HUMAN,tr|A0A7I2YQ88|A0A7I2YQ88_HUMAN,tr|E5RH24|E5RH24_HUMAN,tr|H0YBN4|H0YBN4_HUMAN,tr|E5RGH3|E5RGH3_HUMAN,tr|A0A087WTT1|A0A087WTT1_HUMAN,tr|A0A7I2YQ90|A0A7I2YQ90_HUMAN,tr|E7EQV3|E7EQV3_HUMAN" 17 1436.6684 1.83 46687 12434 2 1436.664727 719.3415 Polyadenylate-binding protein 4 OS=Homo sapiens OX=9606 GN=PABPC4 PE=1 SV=1 4.37 2436 - 436768 - - - -2.5858 - 2.238 0.491 - 227 1 1 0 -0.0037 12 0 0 0 1.13E+07 6.19E+06 - - - 4.786 0.9998 221125_WJC_METTL3_EV_vs_WT_F04.12436.12436.2 0.000348 22-Nov K.SIIQSAQQDSIK[136.11].K sp|Q92616|GCN1_HUMAN 1 1324.7078 1.22 46689 12436 2 1324.708856 663.3612 eIF-2-alpha kinase activator GCN1 OS=Homo sapiens OX=9606 GN=GCN1 PE=1 SV=6 5.55 2436.2 - 337127 - - - 0.8009 - 2.21 0.426 - 376.7 1 2 0 0.0011 12 0 0 0 1.01E+07 8.32E+06 - - - 4.2736 0.9993 221125_WJC_METTL3_EV_vs_WT_F04.12437.12437.3 0.00358 Nov-40 R.GDQTVLILHAK[136.11].V "sp|Q06330|SUH_HUMAN,tr|D6RCM1|D6RCM1_HUMAN,tr|A0A7P0TA33|A0A7P0TA33_HUMAN,tr|D6RAT2|D6RAT2_HUMAN,tr|A0A7P0Z4N7|A0A7P0Z4N7_HUMAN,tr|D6R9K5|D6R9K5_HUMAN,tr|D6RF98|D6RF98_HUMAN,tr|D6R9X3|D6R9X3_HUMAN,tr|D6REC2|D6REC2_HUMAN,tr|D6RA45|D6RA45_HUMAN,tr|D6RB37|D6RB37_HUMAN,tr|D6R946|D6R946_HUMAN,tr|D6RIV8|D6RIV8_HUMAN,tr|A0A7P0T7Z3|A0A7P0T7Z3_HUMAN,tr|D6R927|D6R927_HUMAN,tr|A0A7P0T9W9|A0A7P0T9W9_HUMAN,tr|A0A7P0T9Y9|A0A7P0T9Y9_HUMAN,tr|D6RIZ8|D6RIZ8_HUMAN,tr|D6RBQ8|D6RBQ8_HUMAN,tr|D6REP3|D6REP3_HUMAN,tr|A0A7P0T947|A0A7P0T947_HUMAN,tr|A0A7P0T821|A0A7P0T821_HUMAN,tr|A0A7P0TBJ4|A0A7P0TBJ4_HUMAN,tr|A0A7P0T806|A0A7P0T806_HUMAN,tr|A0A7P0T964|A0A7P0T964_HUMAN,tr|A0A7P0T848|A0A7P0T848_HUMAN" 26 1201.691 7.55 46690 12437 3 1201.691 401.571 Recombining binding protein suppressor of hairless OS=Homo sapiens OX=9606 GN=RBPJ PE=1 SV=3 6.74 2436.4 - 212809 - - - -0.0183 - 1.727 0.314 - 138 1 2 0 0 11 0 0 0 4.67E+07 6.19E+06 - - - 3.593 0.9998 221125_WJC_METTL3_EV_vs_WT_F04.12441.12441.2 1.80E-06 22-Dec K.VAQVAEITYGQK.V "sp|O94905|ERLN2_HUMAN,tr|E5RHW4|E5RHW4_HUMAN,tr|E5RJ09|E5RJ09_HUMAN" 3 1305.6929 1.32 46692 12441 2 1305.694461 653.8537 Erlin-2 OS=Homo sapiens OX=9606 GN=ERLIN2 PE=1 SV=1 5.97 2436.8 - 763993 - - - 1.2216 - 2.436 0.497 - 606 1 2 0 0.0016 12 0 0 0 3.63E+07 2.74E+07 - - - 5.054 0.9994 221125_WJC_METTL3_EV_vs_WT_F04.12442.12442.2 0.000187 18-Aug K.DYTVTQVPPK.H "sp|Q8N5Z5|KCD17_HUMAN,tr|A0A087WX35|A0A087WX35_HUMAN,tr|H0Y731|H0Y731_HUMAN" 3 1146.5921 2.5 46693 12442 2 1146.594528 574.3033 BTB\POZ domain-containing protein KCTD17 OS=Homo sapiens OX=9606 GN=KCTD17 PE=1 SV=3 5.83 2436.9 - 472356 - - - 2.1263 - 1.655 0.472 - 207 1 2 0 0.0024 10 0 0 0 5.56E+06 2.23E+06 - - - 3.9327 0.997 221125_WJC_METTL3_EV_vs_WT_F04.12443.12443.2 0.456 18-Nov K.ISDIQSQLEK.L sp|Q9NVP1|DDX18_HUMAN 1 1159.6085 0.53 46694 12443 2 1159.611914 580.8115 ATP-dependent RNA helicase DDX18 OS=Homo sapiens OX=9606 GN=DDX18 PE=1 SV=2 4.37 2436.9 - 1.19E+06 - - - 2.9717 - 2.319 0.183 - 281 1 2 0 0.0034 10 0 0 0 8.84E+06 1.66E+07 - - - 2.7394 0.9999 221125_WJC_METTL3_EV_vs_WT_F04.12445.12445.2 0.00207 16-Nov K.KLDEEALLK.K sp|O43290|SNUT1_HUMAN 1 1057.6019 2.92 46696 12445 2 1057.601927 529.8082 U4\U6.U5 tri-snRNP-associated protein 1 OS=Homo sapiens OX=9606 GN=SART1 PE=1 SV=1 4.68 2437.2 - 754676 - - - 0.0009 - 2.437 0.469 - 400.6 1 2 0 0 9 0 0 0 8.01E+06 2.74E+06 - - - 5.0821 0.9989 221125_WJC_METTL3_EV_vs_WT_F04.12446.12446.3 0.00731 Aug-48 R.LIAHAGSLTNLAK.Y "sp|O00567|NOP56_HUMAN,tr|A0A494C128|A0A494C128_HUMAN,tr|H0YDU4|H0YDU4_HUMAN,tr|H0Y653|H0Y653_HUMAN" 4 1307.7561 1.02 46697 12446 3 1307.757119 436.926 Nucleolar protein 56 OS=Homo sapiens OX=9606 GN=NOP56 PE=1 SV=4 8.76 2437.3 - 661201 - - - 0.7524 - 2.118 0.249 - 75.1 2 2 0 0.001 13 0 0 0 1.48E+07 1.45E+07 - - - 3.2113 0.9974 221125_WJC_METTL3_EV_vs_WT_F04.12447.12447.3 0.0777 Sep-44 R.IRELEEAMAGER.D sp|Q03252|LMNB2_HUMAN 1 1402.6875 0.51 46698 12447 3 1402.687696 468.5698 Lamin-B2 OS=Homo sapiens OX=9606 GN=LMNB2 PE=1 SV=4 4.49 2437.4 - 524422 - - - 0.1661 - 1.788 0.32 - 117.1 1 2 1 0.0002 12 0 0 0 3.12E+06 6.13E+06 - - - 3.7183 0.9987 221125_WJC_METTL3_EV_vs_WT_F04.12449.12449.2 0.00172 20-Aug K.GNDPNVSLVPK.D sp|P48634|PRC2A_HUMAN 1 1138.5982 1.83 46700 12449 2 1138.599941 570.3064 Protein PRRC2A OS=Homo sapiens OX=9606 GN=PRRC2A PE=1 SV=3 5.84 2437.6 - 352630 - - - 1.4957 - 1.48 0.339 - 194 1 2 0 0.0017 11 0 0 0 1.90E+07 1.04E+07 - - - 2.6049 0.9994 221125_WJC_METTL3_EV_vs_WT_F04.12450.12450.2 0.00123 24-Oct K.ASLEGNLAETENR.Y "sp|Q04695|K1C17_HUMAN,tr|F5GWP8|F5GWP8_HUMAN" 2 1402.6688 78.04 46701 12450 2 1402.672078 702.3417 "Keratin, type I cytoskeletal 17 OS=Homo sapiens OX=9606 GN=KRT17 PE=1 SV=2" 4.25 2437.7 - 334229 - - - 2.3113 - 1.977 0.425 - 139.7 1 2 0 0.0032 13 0 0 0 4.42E+06 5.66E+04 - - - 3.9283 0.9811 221125_WJC_METTL3_EV_vs_WT_F04.12451.12451.3 0.101 Nov-36 K.GKPVLELPER.K "sp|Q14527|HLTF_HUMAN,tr|H7C5K0|H7C5K0_HUMAN,tr|A0A0C4DGA6|A0A0C4DGA6_HUMAN" 3 1136.6554 0.04 46702 12451 3 1137.658419 379.8924 Helicase-like transcription factor OS=Homo sapiens OX=9606 GN=HLTF PE=1 SV=2 6.14 2437.9 - 181047 - - - 882.4663 - 2.07 0.277 - 166.7 1 2 0 1.0031 10 0 0 0 6.90E+05 1.85E+07 - - - 3.4752 1 221125_WJC_METTL3_EV_vs_WT_F04.12454.12454.3 4.03E-06 17/40 R.FPGQLNADLRK.L "sp|P04350|TBB4A_HUMAN,sp|Q9BVA1|TBB2B_HUMAN,sp|A6NNZ2|TBB8B_HUMAN,sp|P07437|TBB5_HUMAN,sp|Q13509|TBB3_HUMAN,sp|Q13885|TBB2A_HUMAN,sp|P68371|TBB4B_HUMAN,sp|Q9BUF5|TBB6_HUMAN,sp|Q3ZCM7|TBB8_HUMAN,sp|Q9H4B7|TBB1_HUMAN,tr|M0R2D3|M0R2D3_HUMAN,tr|A0A0B4J269|A0A0B4J269_HUMAN,tr|Q5ST81|Q5ST81_HUMAN,tr|Q5JP53|Q5JP53_HUMAN,tr|K7ESM5|K7ESM5_HUMAN,tr|A0A075B736|A0A075B736_HUMAN,tr|G3V2A3|G3V2A3_HUMAN,tr|Q5SQY0|Q5SQY0_HUMAN" 18 1257.683 2.38 46703 12454 3 1257.68338 420.2349 Tubulin beta-4A chain OS=Homo sapiens OX=9606 GN=TUBB4A PE=1 SV=2 8.75 2438.3 - 2.15E+06 - - - 0.326 - 2.666 0.488 - 311.7 1 2 0 0.0004 11 0 0 0 3.45E+08 1.45E+08 - - - 6.7663 0.9997 221125_WJC_METTL3_EV_vs_WT_F04.12455.12455.2 0.000237 22-Nov K.GQEVETSVTYYR.L "sp|O43169|CYB5B_HUMAN,tr|D6RFH4|D6RFH4_HUMAN,tr|H3BUX2|H3BUX2_HUMAN" 3 1430.6678 1.18 46704 12455 2 1430.6644 716.3412 Cytochrome b5 type B OS=Homo sapiens OX=9606 GN=CYB5B PE=1 SV=3 4.53 2438.4 - 1.24E+06 - - - -2.3583 - 2.39 0.54 - 198 1 2 0 -0.0034 12 0 0 0 3.01E+07 2.54E+07 - - - 5.3209 0.9998 221125_WJC_METTL3_EV_vs_WT_F04.12456.12456.2 0.0961 22-Oct K.VAQVAEITYGQK[136.11].V "sp|O94905|ERLN2_HUMAN,tr|E5RHW4|E5RHW4_HUMAN,tr|E5RJ09|E5RJ09_HUMAN" 3 1313.7071 1.32 46705 12456 2 1313.708054 657.8608 Erlin-2 OS=Homo sapiens OX=9606 GN=ERLIN2 PE=1 SV=1 5.97 2438.4 - 1.49E+06 - - - 0.7521 - 2.301 0.409 - 364.3 1 2 0 0.001 12 0 0 0 3.63E+07 2.74E+07 - - - 4.2542 0.9993 221125_WJC_METTL3_EV_vs_WT_F04.12458.12458.2 0.379 20-Dec K.SDLLGKPLGPR.T "sp|Q8IY67|RAVR1_HUMAN,tr|E9PAU2|E9PAU2_HUMAN,tr|A0A087WZ13|A0A087WZ13_HUMAN" 3 1151.6663 0.88 46707 12458 2 1151.667958 576.8404 Ribonucleoprotein PTB-binding 1 OS=Homo sapiens OX=9606 GN=RAVER1 PE=1 SV=1 8.46 2438.6 - 1.12E+06 - - - 1.4761 - 2.083 0.294 - 488.6 1 2 0 0.0017 11 0 0 0 3.67E+07 4.18E+07 - - - 3.1971 0.9993 221125_WJC_METTL3_EV_vs_WT_F04.12459.12459.2 9.33E-05 18-Sep R.ESYEVSLTQK[136.11].T "sp|Q9NX40|OCAD1_HUMAN,tr|D6RDK6|D6RDK6_HUMAN,tr|D6RBN5|D6RBN5_HUMAN" 3 1190.591 1.09 46708 12459 2 1190.594435 596.3028 OCIA domain-containing protein 1 OS=Homo sapiens OX=9606 GN=OCIAD1 PE=1 SV=1 4.53 2438.7 - 1.05E+06 - - - 2.8574 - 1.798 0.498 - 206.8 1 2 0 0.0034 10 0 0 0 1.52E+07 1.39E+07 - - - 4.3557 0.9999 221125_WJC_METTL3_EV_vs_WT_F04.12461.12461.3 0.000283 13/48 R.LIAHAGSLTNLAK[136.11].Y "sp|O00567|NOP56_HUMAN,tr|A0A494C128|A0A494C128_HUMAN,tr|H0YDU4|H0YDU4_HUMAN,tr|H0Y653|H0Y653_HUMAN" 4 1315.7703 1.02 46710 12461 3 1315.770736 439.5974 Nucleolar protein 56 OS=Homo sapiens OX=9606 GN=NOP56 PE=1 SV=4 8.76 2438.9 - 682379 - - - 0.3048 - 2.248 0.378 - 194 1 2 0 0.0004 13 0 0 0 1.48E+07 1.45E+07 - - - 4.9505 0.9996 221125_WJC_METTL3_EV_vs_WT_F04.12462.12462.2 0.0526 28-Oct K.VPEVPTAPATDAAPK[136.11].R "sp|Q9UHD8|SEPT9_HUMAN,tr|K7EJ51|K7EJ51_HUMAN" 2 1470.781 1.04 46711 12462 2 1470.781063 736.3978 Septin-9 OS=Homo sapiens OX=9606 GN=SEPTIN9 PE=1 SV=2 4.37 2439.1 - 344991 - - - 0.07 - 1.756 0.392 - 236.8 1 2 0 0.0001 15 0 0 0 5.72E+06 5.51E+06 - - - 3.3205 0.9992 221125_WJC_METTL3_EV_vs_WT_F04.12463.12463.2 0.000321 18-Sep K.QGLDSFDTGK.G "sp|Q14241|ELOA1_HUMAN,tr|A0A024RAC6|A0A024RAC6_HUMAN" 2 1066.4931 1.02 46712 12463 2 1066.495812 534.2538 Elongin-A OS=Homo sapiens OX=9606 GN=ELOA PE=1 SV=2 4.21 2439.2 - 303589 - - - 2.5392 - 1.651 0.451 - 248.6 1 2 0 0.0027 10 0 0 0 1.86E+07 1.81E+07 - - - 3.7707 0.9999 221125_WJC_METTL3_EV_vs_WT_F04.12466.12466.3 0.00465 Nov-40 R.QTVEADVNGLR.R sp|P08779|K1C16_HUMAN 1 1200.6099 111.41 46713 12466 3 1200.610337 401.2106 "Keratin, type I cytoskeletal 16 OS=Homo sapiens OX=9606 GN=KRT16 PE=1 SV=4" 4.37 2439.6 - 1.68E+06 - - - 0.3931 - 2.07 0.404 - 226.5 1 2 0 0.0005 11 0 0 0 4.74E+07 4.25E+05 - - - 5.1109 0.9999 221125_WJC_METTL3_EV_vs_WT_F04.12467.12467.2 8.67E-05 20-Dec K.SDLLGK[136.11]PLGPR[166.11].T "sp|Q8IY67|RAVR1_HUMAN,tr|E9PAU2|E9PAU2_HUMAN,tr|A0A087WZ13|A0A087WZ13_HUMAN" 3 1169.6887 0.88 46714 12467 2 1169.689282 585.8516 Ribonucleoprotein PTB-binding 1 OS=Homo sapiens OX=9606 GN=RAVER1 PE=1 SV=1 8.46 2439.7 - 1.63E+06 - - - 0.4736 - 2.219 0.478 - 448.3 1 2 0 0.0006 11 0 0 0 3.67E+07 4.18E+07 - - - 4.7276 0.9995 221125_WJC_METTL3_EV_vs_WT_F04.12468.12468.2 0.00223 22-Sep K.NAC[160.03]LQTSSLAVR.V "sp|Q6P3W7|SCYL2_HUMAN,tr|F8VSC5|F8VSC5_HUMAN,tr|H0YI32|H0YI32_HUMAN,tr|A0A0U1RQQ9|A0A0U1RQQ9_HUMAN" 4 1318.6663 4.45 46715 12468 2 1318.668045 660.3404 SCY1-like protein 2 OS=Homo sapiens OX=9606 GN=SCYL2 PE=1 SV=1 8.25 2439.7 - 1.14E+06 - - - 1.2975 - 1.898 0.375 - 212.4 1 2 0 0.0017 12 0 0 0 3.27E+07 7.36E+06 - - - 3.4963 0.9937 221125_WJC_METTL3_EV_vs_WT_F04.12469.12469.3 0.00208 14/48 K.LLDELSPNTAPHK.Y "sp|P22830|HEMH_HUMAN,tr|A0A499FJN5|A0A499FJN5_HUMAN,tr|K7ELX4|K7ELX4_HUMAN" 3 1433.7514 1.03 46716 12469 3 1433.752328 478.9244 "Ferrochelatase, mitochondrial OS=Homo sapiens OX=9606 GN=FECH PE=1 SV=2" 5.32 2439.8 - 849720 - - - 0.6166 - 2.092 0.139 - 232 1 2 0 0.0009 13 0 0 0 1.14E+07 1.11E+07 - - - 2.0907 0.9996 221125_WJC_METTL3_EV_vs_WT_F04.12470.12470.3 0.0024 Nov-48 K.LLDELSPNTAPHK[136.11].Y "sp|P22830|HEMH_HUMAN,tr|A0A499FJN5|A0A499FJN5_HUMAN,tr|K7ELX4|K7ELX4_HUMAN" 3 1441.7656 1.19 46717 12470 3 1441.76715 481.5958 "Ferrochelatase, mitochondrial OS=Homo sapiens OX=9606 GN=FECH PE=1 SV=2" 5.32 2439.9 - 530960 - - - 1.0446 - 1.922 0.344 - 165.2 1 2 0 0.0015 13 0 0 0 1.23E+07 1.03E+07 - - - 4.1463 0.9998 221125_WJC_METTL3_EV_vs_WT_F04.12473.12473.3 0.000266 Oct-40 K.YSLIVAQHVEK[136.11].E "sp|Q13439|GOGA4_HUMAN,tr|H0Y6I0|H0Y6I0_HUMAN" 2 1293.7172 0.13 46720 12473 3 1293.71617 432.2464 Golgin subfamily A member 4 OS=Homo sapiens OX=9606 GN=GOLGA4 PE=1 SV=1 6.75 2440.3 - 360101 - - - -0.8248 - 1.731 0.422 - 85.3 1 2 0 -0.0011 11 0 0 0 6.36E+06 4.89E+07 - - - 4.8033 0.9952 221125_WJC_METTL3_EV_vs_WT_F04.12475.12475.3 0.00522 Oct-36 K.K[136.11]PEMFETAIK[136.11].E "sp|P78347|GTF2I_HUMAN,tr|A0A494C1K3|A0A494C1K3_HUMAN" 2 1208.6446 1.44 46721 12475 3 1208.647622 403.8888 General transcription factor II-I OS=Homo sapiens OX=9606 GN=GTF2I PE=1 SV=2 6.14 2440.6 - 200681 - - - 2.5036 - 1.741 0.247 - 128.6 1 2 0 0.003 10 0 0 0 3.82E+08 2.66E+08 - - - 2.9122 0.9999 221125_WJC_METTL3_EV_vs_WT_F04.12477.12477.3 1.97E-06 17/44 R.VMEIVDADEK[136.11]VR[166.11].H sp|Q9Y5B9|SP16H_HUMAN 1 1420.7351 0.77 46722 12477 3 1420.735643 474.5856 FACT complex subunit SPT16 OS=Homo sapiens OX=9606 GN=SUPT16H PE=1 SV=1 4.32 2440.8 - 961910 - - - 0.3921 - 3.046 0.542 - 510.6 1 2 1 0.0006 12 0 0 0 7.83E+06 1.02E+07 - - - 7.67 0.9994 221125_WJC_METTL3_EV_vs_WT_F04.12478.12478.3 0.00241 Aug-40 K.AEELHYPLGER.R "sp|Q14257|RCN2_HUMAN,tr|H0YL43|H0YL43_HUMAN,tr|A8MXP8|A8MXP8_HUMAN" 3 1312.6412 0.92 46723 12478 3 1312.64146 438.5543 Reticulocalbin-2 OS=Homo sapiens OX=9606 GN=RCN2 PE=1 SV=1 4.75 2440.9 - 782679 - - - 0.2247 - 1.756 0.315 - 103.2 1 2 0 0.0003 11 0 0 0 1.32E+07 1.43E+07 - - - 3.6514 0.9999 221125_WJC_METTL3_EV_vs_WT_F04.12479.12479.2 1.03E-08 17/26 K.VASPDAVTTITSSK[136.11].L sp|Q9NUL7|DDX28_HUMAN 1 1383.7337 0.86 46724 12479 2 1383.733977 692.8741 Probable ATP-dependent RNA helicase DDX28 OS=Homo sapiens OX=9606 GN=DDX28 PE=1 SV=2 5.81 2441 - 969324 - - - 0.2183 - 3.181 0.476 - 1113.6 1 2 0 0.0003 14 0 0 0 1.87E+07 2.17E+07 - - - 5.4606 0.9981 221125_WJC_METTL3_EV_vs_WT_F04.12480.12480.3 9.25E-07 17/44 R.VMEIVDADEKVR.H sp|Q9Y5B9|SP16H_HUMAN 1 1402.7126 0.64 46725 12480 3 1402.717776 468.5781 FACT complex subunit SPT16 OS=Homo sapiens OX=9606 GN=SUPT16H PE=1 SV=1 4.32 2441 - 872347 - - - 3.6786 - 2.794 0.379 - 547.9 1 2 1 0.0052 12 0 0 0 8.66E+06 1.36E+07 - - - 5.6121 0.9998 221125_WJC_METTL3_EV_vs_WT_F04.12481.12481.2 2.53E-05 20-Oct K.TYNEPGSQVFK[136.11].D "sp|Q86U86|PB1_HUMAN,tr|H0Y5B5|H0Y5B5_HUMAN,tr|E7EVG2|E7EVG2_HUMAN" 3 1276.6179 1.6 46726 12481 2 1276.617797 639.3162 Protein polybromo-1 OS=Homo sapiens OX=9606 GN=PBRM1 PE=1 SV=1 5.66 2441.2 - 660293 - - - -0.094 - 1.786 0.464 - 219.9 1 2 0 -0.0001 11 0 0 0 3.05E+07 1.91E+07 - - - 4.037 0.9936 221125_WJC_METTL3_EV_vs_WT_F04.12482.12482.2 0.0105 16-Aug R.K[136.11]VEAPFIPK[136.11].F "sp|P22694|KAPCB_HUMAN,sp|P22612|KAPCG_HUMAN,sp|P17612|KAPCA_HUMAN,tr|A0A087WVC4|A0A087WVC4_HUMAN,tr|A0A7I2V5J4|A0A7I2V5J4_HUMAN,tr|K7ERP6|K7ERP6_HUMAN,tr|A0A0A0MS54|A0A0A0MS54_HUMAN" 7 1043.635 1.21 46727 12482 2 1043.636138 522.8248 cAMP-dependent protein kinase catalytic subunit beta OS=Homo sapiens OX=9606 GN=PRKACB PE=1 SV=2 8.59 2441.3 - 528180 - - - 1.0741 - 1.613 0.098 - 191.3 1 2 0 0.0011 9 0 0 0 9.69E+06 8.04E+06 - - - 1.1476 1 221125_WJC_METTL3_EV_vs_WT_F04.12483.12483.2 9.16E-06 20-Dec K.SMYEEEINETR.R "sp|P20700|LMNB1_HUMAN,tr|E9PBF6|E9PBF6_HUMAN,tr|A0A0D9SFE5|A0A0D9SFE5_HUMAN" 3 1399.5926 1.17 46728 12483 2 1399.593951 700.8036 Lamin-B1 OS=Homo sapiens OX=9606 GN=LMNB1 PE=1 SV=2 4.09 2441.4 - 473659 - - - 0.9939 - 2.464 0.61 - 606.8 1 2 0 0.0014 11 0 0 0 1.95E+07 1.67E+07 - - - 5.9856 0.9999 221125_WJC_METTL3_EV_vs_WT_F04.12484.12484.3 2.38E-06 14/48 R.NREEEWDPEYTPK.S "sp|Q9Y2W1|TR150_HUMAN,tr|A0A3B3ITZ9|A0A3B3ITZ9_HUMAN" 2 1691.7427 4.3 46729 12484 3 1691.745424 564.9215 Thyroid hormone receptor-associated protein 3 OS=Homo sapiens OX=9606 GN=THRAP3 PE=1 SV=2 4.25 2441.6 - 380144 - - - 1.5924 - 2.623 0.625 - 408.6 1 2 1 0.0027 13 0 0 0 8.86E+06 2.06E+06 - - - 8.1219 0.9998 221125_WJC_METTL3_EV_vs_WT_F04.12486.12486.2 0.000144 13/24 R.IEADSESQEDIIR[166.11].N sp|P55957|BID_HUMAN 1 1513.7136 0.8 46731 12486 2 1513.711663 757.8641 BH3-interacting domain death agonist OS=Homo sapiens OX=9606 GN=BID PE=1 SV=1 3.83 2441.8 - 283601 - - - -1.2479 - 2.864 0.406 - 655.9 1 2 0 -0.0019 13 0 0 0 3.09E+06 3.85E+06 - - - 4.7397 0.9952 221125_WJC_METTL3_EV_vs_WT_F04.12487.12487.3 0.00417 13/48 R.LAALTQGSYLHQR[166.11].V "sp|Q9Y4R8|TELO2_HUMAN,tr|H3BRS3|H3BRS3_HUMAN" 2 1466.7869 0.12 46732 12487 3 1466.791712 489.9363 Telomere length regulation protein TEL2 homolog OS=Homo sapiens OX=9606 GN=TELO2 PE=1 SV=2 8.75 2441.9 - 232874 - - - 3.2588 - 1.939 0.264 - 263.1 1 2 0 0.0048 13 0 0 0 2.33E+05 1.93E+06 - - - 3.2774 1 221125_WJC_METTL3_EV_vs_WT_F04.12491.12491.3 0.000838 16/48 R.LLEGEDAHLTQYK.K "sp|Q04695|K1C17_HUMAN,tr|A0A3B3IS58|A0A3B3IS58_HUMAN,tr|F5GWP8|F5GWP8_HUMAN" 3 1515.7569 9248.38 46734 12491 3 1515.758783 506.2596 "Keratin, type I cytoskeletal 17 OS=Homo sapiens OX=9606 GN=KRT17 PE=1 SV=2" 4.65 2442.5 - 1.91E+06 - - - 1.2271 - 3.422 0.509 - 323.7 1 2 0 0.0019 13 0 0 0 7.45E+08 8.06E+04 - - - 7.5498 0.9996 221125_WJC_METTL3_EV_vs_WT_F04.12492.12492.2 0.00167 16-Jul R.C[160.03]QLPDGSFR.R "sp|O75643|U520_HUMAN,tr|A0A494C1A5|A0A494C1A5_HUMAN" 2 1078.4866 1.51 46735 12492 2 1078.48709 540.2506 U5 small nuclear ribonucleoprotein 200 kDa helicase OS=Homo sapiens OX=9606 GN=SNRNP200 PE=1 SV=2 5.83 2442.6 - 1.01E+06 - - - 0.4738 - 1.404 0.45 - 176.9 1 2 0 0.0005 9 0 0 0 1.47E+07 9.74E+06 - - - 3.3462 0.9984 221125_WJC_METTL3_EV_vs_WT_F04.12493.12493.3 0.0121 Oct-32 K.DFDREVEIR.L sp|Q53HL2|BOREA_HUMAN 1 1177.5728 0.61 46736 12493 3 1177.571914 393.5315 Borealin OS=Homo sapiens OX=9606 GN=CDCA8 PE=1 SV=2 4.32 2442.6 - 1.93E+06 - - - -0.7108 - 1.706 0.354 - 178.7 1 2 1 -0.0008 9 0 0 0 3.54E+07 5.82E+07 - - - 4.0963 0.9939 221125_WJC_METTL3_EV_vs_WT_F04.12494.12494.2 2.60E-06 13/20 R.C[160.03]SAGLGALAQR[166.11].P "sp|Q9NXV2|KCTD5_HUMAN,tr|H3BSS5|H3BSS5_HUMAN" 2 1112.5636 3.31 46737 12494 2 1112.563151 557.2891 BTB\POZ domain-containing protein KCTD5 OS=Homo sapiens OX=9606 GN=KCTD5 PE=1 SV=1 8.25 2442.8 - 879141 - - - -0.4009 - 2.401 0.516 - 765.6 1 1 0 -0.0004 11 0 0 0 3.76E+07 1.14E+07 - - - 5.2215 0.9998 221125_WJC_METTL3_EV_vs_WT_F04.12495.12495.3 0.00106 Oct-40 K.AEELHYPLGER[166.11].R "sp|Q14257|RCN2_HUMAN,tr|H0YL43|H0YL43_HUMAN,tr|A8MXP8|A8MXP8_HUMAN" 3 1322.6494 0.9 46738 12495 3 1322.650273 441.8904 Reticulocalbin-2 OS=Homo sapiens OX=9606 GN=RCN2 PE=1 SV=1 4.75 2442.9 - 830701 - - - 0.6336 - 2.021 0.369 - 160.2 1 2 0 0.0008 11 0 0 0 1.34E+07 1.49E+07 - - - 4.6525 0.9001 221125_WJC_METTL3_EV_vs_WT_F04.12496.12496.2 0.0271 18-Aug S.DLLGK[136.11]PLGPR[166.11].T "sp|Q8IY67|RAVR1_HUMAN,tr|E9PAU2|E9PAU2_HUMAN,tr|A0A087WZ13|A0A087WZ13_HUMAN" 3 1082.6567 1.06 46739 12496 2 1082.657924 542.3356 Ribonucleoprotein PTB-binding 1 OS=Homo sapiens OX=9606 GN=RAVER1 PE=1 SV=1 8.75 2443 - 827507 - - - 1.1315 - 1.431 0.284 - 260.7 1 1 0 0.0012 10 0 0 0 6.43E+06 6.05E+06 - - - 2.1386 0.9999 221125_WJC_METTL3_EV_vs_WT_F04.12502.12502.2 0.00124 18-Nov K.QGLDSFDTGK[136.11].G "sp|Q14241|ELOA1_HUMAN,tr|A0A024RAC6|A0A024RAC6_HUMAN" 2 1074.5073 1.02 46744 12502 2 1074.507322 538.2609 Elongin-A OS=Homo sapiens OX=9606 GN=ELOA PE=1 SV=2 4.21 2443.6 - 1.69E+06 - - - 0.0168 - 2.309 0.448 - 390 1 2 0 0 10 0 0 0 1.86E+07 1.81E+07 - - - 4.6857 0.9998 221125_WJC_METTL3_EV_vs_WT_F04.12503.12503.2 1.97E-06 16/26 K.VASPDAVTTITSSK.L sp|Q9NUL7|DDX28_HUMAN 1 1375.7195 0.86 46745 12503 2 1375.719441 688.867 Probable ATP-dependent RNA helicase DDX28 OS=Homo sapiens OX=9606 GN=DDX28 PE=1 SV=2 5.81 2443.7 - 1.53E+06 - - - -0.0247 - 2.95 0.364 - 1151.1 1 2 0 0 14 0 0 0 1.87E+07 2.17E+07 - - - 4.4442 0.9996 221125_WJC_METTL3_EV_vs_WT_F04.12504.12504.2 0.000454 14-Jul R.NTFNFGSK[136.11].N sp|P49792|RBP2_HUMAN 1 921.4436 0.68 46746 12504 2 921.443706 461.7291 E3 SUMO-protein ligase RanBP2 OS=Homo sapiens OX=9606 GN=RANBP2 PE=1 SV=2 8.75 2443.8 - 1.08E+06 - - - 0.1357 - 1.528 0.405 - 208 1 2 0 0.0001 8 0 0 0 7.42E+06 1.09E+07 - - - 3.3109 0.9997 221125_WJC_METTL3_EV_vs_WT_F04.12506.12506.2 0.00139 16-Sep R.QLDSIVGER.G "sp|P48668|K2C6C_HUMAN,sp|P13647|K2C5_HUMAN,sp|P02538|K2C6A_HUMAN,tr|F8W0C6|F8W0C6_HUMAN" 4 1015.5298 283.21 46748 12506 2 1015.530611 508.7722 "Keratin, type II cytoskeletal 6C OS=Homo sapiens OX=9606 GN=KRT6C PE=1 SV=3" 4.37 2444 - 847384 - - - 0.775 - 1.953 0.38 - 363.1 1 2 0 0.0008 9 0 0 0 1.12E+08 3.96E+05 - - - 3.7839 1 221125_WJC_METTL3_EV_vs_WT_F04.12507.12507.3 6.22E-05 17/56 K.SLGPLHAAAAAAAPR.R sp|Q9H2Z4|NKX24_HUMAN 1 1372.7575 2.15 46749 12507 3 1372.758594 458.5931 Homeobox protein Nkx-2.4 OS=Homo sapiens OX=9606 GN=NKX2-4 PE=1 SV=3 9.49 2444.1 - 788614 - - - 0.7736 - 2.78 0.458 - 135 1 2 0 0.0011 15 0 0 0 2.31E+07 1.08E+07 - - - 6.3139 0.9848 221125_WJC_METTL3_EV_vs_WT_F04.12509.12509.3 0.238 Nov-52 K.VLSEDK[136.11]EVLSAEVK[136.11].S "sp|Q8IWJ2|GCC2_HUMAN,tr|B8ZZW2|B8ZZW2_HUMAN" 2 1560.8582 1.97 46751 12509 3 1560.860801 521.2933 GRIP and coiled-coil domain-containing protein 2 OS=Homo sapiens OX=9606 GN=GCC2 PE=1 SV=4 4.41 2444.3 - 442145 - - - 1.6959 - 1.774 0.246 - 105.3 1 2 1 0.0026 14 0 0 0 9.86E+06 5.00E+06 - - - 2.8053 1 221125_WJC_METTL3_EV_vs_WT_F04.12511.12511.2 6.05E-06 13/24 R.IEADSESQEDIIR.N sp|P55957|BID_HUMAN 1 1503.7053 0.82 46753 12511 2 1503.710381 752.8599 BH3-interacting domain death agonist OS=Homo sapiens OX=9606 GN=BID PE=1 SV=1 3.83 2444.6 - 282441 - - - 3.391 - 2.838 0.556 - 673.2 1 2 0 0.0051 13 0 0 0 3.09E+06 3.79E+06 - - - 5.8232 0.9932 221125_WJC_METTL3_EV_vs_WT_F04.12512.12512.2 0.244 18-Sep K.SIINSMSESR[166.11].D sp|Q9H7X7|IFT22_HUMAN 1 1132.5422 0.09 46754 12512 2 1132.542324 567.2784 Intraflagellar transport protein 22 homolog OS=Homo sapiens OX=9606 GN=IFT22 PE=1 SV=1 5.72 2444.7 - 237371 - - - 0.1157 - 1.413 0.12 - 142.1 1 2 0 0.0001 10 0 0 0 4.06E+05 4.46E+06 - - - 0.8923 0.9996 221125_WJC_METTL3_EV_vs_WT_F04.12517.12517.2 0.523 14-Oct R.EHLLDQLK.R "sp|P52732|KIF11_HUMAN,tr|A0A7I2V3A9|A0A7I2V3A9_HUMAN" 2 994.5447 5.48 46757 12517 2 994.545292 498.2796 Kinesin-like protein KIF11 OS=Homo sapiens OX=9606 GN=KIF11 PE=1 SV=2 5.32 2445.4 - 7.57E+06 - - - 0.55 - 1.969 0.308 - 523.1 1 2 0 0.0005 8 0 0 0 8.37E+07 1.53E+07 - - - 3.3591 0.8998 221125_WJC_METTL3_EV_vs_WT_F04.12518.12518.2 0.00565 18-Sep K.SDSEVAGYIR.Q "sp|Q9H3G5|CPVL_HUMAN,tr|H7C218|H7C218_HUMAN,tr|H7C0X5|H7C0X5_HUMAN" 3 1095.5197 1.14 46758 12518 2 1096.519812 548.7671 Probable serine carboxypeptidase CPVL OS=Homo sapiens OX=9606 GN=CPVL PE=1 SV=2 4.37 2445.5 - 2.11E+06 - - - 912.954 - 1.733 0.34 - 226.3 1 2 0 1.0002 10 0 0 0 2.27E+07 2.00E+07 - - - 2.773 1 221125_WJC_METTL3_EV_vs_WT_F04.12519.12519.2 6.02E-09 16/24 R.LLEGEDAHLTQYK.K "sp|Q04695|K1C17_HUMAN,tr|A0A3B3IS58|A0A3B3IS58_HUMAN,tr|F5GWP8|F5GWP8_HUMAN" 3 1515.7569 999 46759 12519 2 1515.761681 758.8857 "Keratin, type I cytoskeletal 17 OS=Homo sapiens OX=9606 GN=KRT17 PE=1 SV=2" 4.65 2445.6 - 1.27E+06 - - - 3.139 - 3.165 0.63 - 671.6 1 2 0 0.0048 13 0 0 0 6.07E+07 0.00E+00 - - - 6.6497 0.9987 221125_WJC_METTL3_EV_vs_WT_F04.12520.12520.3 0.21 Dec-36 K.FLPSELRDEH.- sp|Q9Y490|TLN1_HUMAN 1 1241.6041 1.1 46760 12520 3 1241.603568 414.8753 Talin-1 OS=Homo sapiens OX=9606 GN=TLN1 PE=1 SV=3 4.65 2445.7 - 604975 - - - -0.389 - 1.972 0.336 - 145.7 1 2 1 -0.0005 10 0 0 0 6.83E+06 6.21E+06 - - - 4.2691 0.9996 221125_WJC_METTL3_EV_vs_WT_F04.12523.12523.2 0.000723 22-Oct R.LEQYTSAIEGTK[136.11].S "sp|Q05682|CALD1_HUMAN,tr|C9J813|C9J813_HUMAN,tr|E7EX44|E7EX44_HUMAN,tr|A0A6Q8PGI1|A0A6Q8PGI1_HUMAN,tr|E9PGZ1|E9PGZ1_HUMAN" 5 1346.6809 0.6 46763 12523 2 1346.682303 674.3477 Caldesmon OS=Homo sapiens OX=9606 GN=CALD1 PE=1 SV=3 4.53 2446.1 - 492314 - - - 1.0337 - 1.932 0.387 - 146.7 1 2 0 0.0014 12 0 0 0 3.04E+06 5.11E+06 - - - 3.6317 0.9998 221125_WJC_METTL3_EV_vs_WT_F04.12524.12524.2 0.0104 14/18 R.RIDISPSTLR.K "sp|Q9NYF8|BCLF1_HUMAN,tr|E9PKI6|E9PKI6_HUMAN,tr|A0A1W2PQ43|A0A1W2PQ43_HUMAN,tr|E9PK91|E9PK91_HUMAN,tr|E9PK09|E9PK09_HUMAN,tr|E9PQN2|E9PQN2_HUMAN" 6 1156.6564 2.04 46764 12524 2 1156.655615 579.3355 Bcl-2-associated transcription factor 1 OS=Homo sapiens OX=9606 GN=BCLAF1 PE=1 SV=2 9.6 2446.2 - 350808 - - - -0.6968 - 2.424 0.363 - 374.1 1 2 0 -0.0008 10 0 0 0 5.17E+07 2.54E+07 - - - 4.1933 1 221125_WJC_METTL3_EV_vs_WT_F04.12527.12527.2 4.52E-08 20-Dec K.TQVTVQYMQDR.G sp|P31153|METK2_HUMAN 1 1367.6503 1.37 46766 12527 2 1367.65181 684.8325 S-adenosylmethionine synthase isoform type-2 OS=Homo sapiens OX=9606 GN=MAT2A PE=1 SV=1 5.5 2446.5 - 690527 - - - 1.0675 - 2.624 0.579 - 583 1 2 0 0.0015 11 0 0 0 8.88E+06 6.50E+06 - - - 5.9268 0.9999 221125_WJC_METTL3_EV_vs_WT_F04.12529.12529.2 3.89E-06 20-Oct K.SMYEEEINETR[166.11].R "sp|P20700|LMNB1_HUMAN,tr|E9PBF6|E9PBF6_HUMAN,tr|A0A0D9SFE5|A0A0D9SFE5_HUMAN" 3 1409.6008 1.17 46767 12529 2 1409.600749 705.8077 Lamin-B1 OS=Homo sapiens OX=9606 GN=LMNB1 PE=1 SV=2 4.09 2446.8 - 1.39E+06 - - - -0.0575 - 2.296 0.534 - 359.7 1 2 0 -0.0001 11 0 0 0 1.95E+07 1.67E+07 - - - 5.2336 0.9996 221125_WJC_METTL3_EV_vs_WT_F04.12530.12530.3 0.00607 Dec-48 K.LIQEQHPEEELIK[136.11].T "sp|Q13813|SPTN1_HUMAN,tr|A0A0D9SF54|A0A0D9SF54_HUMAN,tr|A0A0D9SGF6|A0A0D9SGF6_HUMAN" 3 1612.8552 1.6 46768 12530 3 1612.856669 538.6257 "Spectrin alpha chain, non-erythrocytic 1 OS=Homo sapiens OX=9606 GN=SPTAN1 PE=1 SV=3" 4.48 2446.8 - 1.43E+06 - - - 0.9189 - 1.661 0.372 - 126.9 1 2 0 0.0015 13 0 0 0 2.58E+07 1.61E+07 - - - 4.0628 0.9988 221125_WJC_METTL3_EV_vs_WT_F04.12531.12531.3 0.0228 Sep-48 K.LIQEQHPEEELIK.T "sp|Q13813|SPTN1_HUMAN,tr|A0A0D9SF54|A0A0D9SF54_HUMAN,tr|A0A0D9SGF6|A0A0D9SGF6_HUMAN" 3 1604.841 1.59 46769 12531 3 1604.841273 535.9543 "Spectrin alpha chain, non-erythrocytic 1 OS=Homo sapiens OX=9606 GN=SPTAN1 PE=1 SV=3" 4.48 2446.9 - 2.01E+06 - - - 0.1782 - 1.734 0.284 - 56.2 1 2 0 0.0003 13 0 0 0 2.58E+07 1.62E+07 - - - 3.1986 1 221125_WJC_METTL3_EV_vs_WT_F04.12534.12534.2 0.00139 22-Dec R.AQVQEFC[160.03]DYGTK[136.11].E "sp|Q86U44|MTA70_HUMAN,tr|H0YFV6|H0YFV6_HUMAN" 2 1452.6435 0.01 46772 12534 2 1452.640103 727.329 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 4.37 2447.1 - 1.06E+06 - - - -2.3247 - 2.551 0.573 - 431.4 1 2 0 -0.0034 12 0 0 0 1.54E+06 1.07E+08 - - - 5.7362 0.9992 221125_WJC_METTL3_EV_vs_WT_F04.12535.12535.3 0.01 Jul-32 R.EWQHEEFYR.Y "sp|Q12931|TRAP1_HUMAN,tr|I3L0K7|I3L0K7_HUMAN,tr|I3L239|I3L239_HUMAN" 3 1322.568 1.65 46773 12535 3 1322.567847 441.8633 "Heat shock protein 75 kDa, mitochondrial OS=Homo sapiens OX=9606 GN=TRAP1 PE=1 SV=3" 4.75 2447.2 - 941825 - - - -0.1157 - 1.52 0.326 - 106.4 1 2 0 -0.0002 9 0 0 0 1.30E+07 7.88E+06 - - - 3.4364 0.9989 221125_WJC_METTL3_EV_vs_WT_F04.12536.12536.3 0.0591 Jul-32 R.EWQHEEFYR[166.11].Y "sp|Q12931|TRAP1_HUMAN,tr|I3L0K7|I3L0K7_HUMAN,tr|I3L239|I3L239_HUMAN" 3 1332.5763 1.64 46774 12536 3 1332.577054 445.1994 "Heat shock protein 75 kDa, mitochondrial OS=Homo sapiens OX=9606 GN=TRAP1 PE=1 SV=3" 4.75 2447.4 - 926154 - - - 0.5883 - 1.612 0.294 - 70.8 1 2 0 0.0008 9 0 0 0 1.28E+07 7.81E+06 - - - 3.2566 1 221125_WJC_METTL3_EV_vs_WT_F04.12537.12537.2 1.31E-08 14/20 L.EGEDAHLTQYK.K "sp|Q04695|K1C17_HUMAN,tr|A0A3B3IS58|A0A3B3IS58_HUMAN,tr|F5GWP8|F5GWP8_HUMAN" 3 1289.5888 126.17 46775 12537 2 1289.594619 645.8017 "Keratin, type I cytoskeletal 17 OS=Homo sapiens OX=9606 GN=KRT17 PE=1 SV=2" 4.65 2447.4 - 915245 - - - 4.5162 - 2.932 0.576 - 891.8 1 1 0 0.0058 11 0 0 0 1.76E+07 1.40E+05 - - - 6.2035 0.9996 221125_WJC_METTL3_EV_vs_WT_F04.12538.12538.3 0.000613 Dec-36 R.LNLHYAVVSK.R "sp|P47897|SYQ_HUMAN,tr|B4DDN1|B4DDN1_HUMAN,tr|H7C0R3|H7C0R3_HUMAN,tr|A0A1B0GTT3|A0A1B0GTT3_HUMAN,tr|A0A1B0GVU9|A0A1B0GVU9_HUMAN,tr|A0A0U1RQQ5|A0A0U1RQQ5_HUMAN" 6 1142.6448 0.12 46776 12538 3 1142.6451 381.8889 Glutamine--tRNA ligase OS=Homo sapiens OX=9606 GN=QARS1 PE=1 SV=1 8.6 2447.5 - 914564 - - - 0.2678 - 2.172 0.289 - 149.2 1 2 0 0.0003 10 0 0 0 7.03E+06 5.89E+07 - - - 4.0272 0.9999 221125_WJC_METTL3_EV_vs_WT_F04.12540.12540.3 9.59E-05 Nov-36 R.C[160.03]PVEIPPIRR.R sp|Q5T749|KPRP_HUMAN 1 1235.6809 47.5 46778 12540 3 1235.681379 412.9009 Keratinocyte proline-rich protein OS=Homo sapiens OX=9606 GN=KPRP PE=1 SV=1 8.25 2447.8 - 771242 - - - 0.4184 - 2.23 0.444 - 269.2 1 2 0 0.0005 10 0 0 0 1.49E+07 3.14E+05 - - - 5.8322 0.9995 221125_WJC_METTL3_EV_vs_WT_F04.12541.12541.2 2.35E-05 14-Nov K.HDLDLIC[160.03]R[166.11].A "sp|P62136|PP1A_HUMAN,sp|P62140|PP1B_HUMAN,sp|P36873|PP1G_HUMAN,tr|A0A7I2V4F7|A0A7I2V4F7_HUMAN,tr|F8W0W8|F8W0W8_HUMAN,tr|F8VYE8|F8VYE8_HUMAN,tr|F8VR82|F8VR82_HUMAN,tr|E9PMD7|E9PMD7_HUMAN" 8 1050.5156 1.31 46779 12541 2 1050.518902 526.2651 Serine\threonine-protein phosphatase PP1-alpha catalytic subunit OS=Homo sapiens OX=9606 GN=PPP1CA PE=1 SV=1 5.21 2447.9 - 630599 - - - 3.1584 - 2.047 0.545 - 356.5 1 2 0 0.0033 8 0 0 0 2.25E+07 1.71E+07 - - - 5.2259 0.9999 221125_WJC_METTL3_EV_vs_WT_F04.12542.12542.2 5.57E-05 13/24 K.FSASGELGNGNIK[136.11].L sp|P12004|PCNA_HUMAN 1 1300.6503 1.75 46780 12542 2 1300.651529 651.3324 Proliferating cell nuclear antigen OS=Homo sapiens OX=9606 GN=PCNA PE=1 SV=1 6 2448 - 571796 - - - 0.9603 - 2.591 0.538 - 376.1 1 2 0 0.0013 13 0 0 0 2.55E+07 1.46E+07 - - - 5.4577 0.9999 221125_WJC_METTL3_EV_vs_WT_F04.12543.12543.2 7.00E-06 13/16 K.HVVFGQVIK[136.11].G sp|Q08752|PPID_HUMAN 1 1033.6164 3.54 46781 12543 2 1033.617421 517.8155 Peptidyl-prolyl cis-trans isomerase D OS=Homo sapiens OX=9606 GN=PPID PE=1 SV=3 8.76 2448.2 - 423028 - - - 0.9868 - 2.176 0.542 - 614 1 2 0 0.001 9 0 0 0 1.00E+07 2.83E+06 - - - 5.2932 0.9998 221125_WJC_METTL3_EV_vs_WT_F04.12544.12544.2 0.000208 13/20 K.QQLEAVNEAIK.S sp|O95347|SMC2_HUMAN 1 1241.6616 1.04 46782 12544 2 1241.662152 621.8381 Structural maintenance of chromosomes protein 2 OS=Homo sapiens OX=9606 GN=SMC2 PE=1 SV=2 4.53 2448.3 - 416510 - - - 0.4719 - 2.469 0.388 - 538.4 1 2 0 0.0006 11 0 0 0 8.92E+06 8.56E+06 - - - 4.3516 0.9995 221125_WJC_METTL3_EV_vs_WT_F04.12547.12547.2 0.00356 16-Sep R.SLYNLGGSK.R "sp|P13647|K2C5_HUMAN,tr|F8VV57|F8VV57_HUMAN" 2 937.4869 999 46785 12547 2 937.486521 469.7507 "Keratin, type II cytoskeletal 5 OS=Homo sapiens OX=9606 GN=KRT5 PE=1 SV=3" 8.31 2448.7 - 305117 - - - -0.4 - 1.555 0.365 - 224.5 1 2 0 -0.0004 9 0 0 0 1.90E+07 0.00E+00 - - - 3.014 0.9999 221125_WJC_METTL3_EV_vs_WT_F04.12552.12552.2 0.00634 14-Dec K.HDLDLIC[160.03]R.A "sp|P62136|PP1A_HUMAN,sp|P62140|PP1B_HUMAN,sp|P36873|PP1G_HUMAN,tr|A0A7I2V4F7|A0A7I2V4F7_HUMAN,tr|F8W0W8|F8W0W8_HUMAN,tr|F8VYE8|F8VYE8_HUMAN,tr|F8VR82|F8VR82_HUMAN,tr|E9PMD7|E9PMD7_HUMAN" 8 1040.5073 1.31 46789 12552 2 1040.507049 521.2609 Serine\threonine-protein phosphatase PP1-alpha catalytic subunit OS=Homo sapiens OX=9606 GN=PPP1CA PE=1 SV=1 5.21 2449.2 - 1.99E+06 - - - -0.2547 - 2.226 0.443 - 493.4 1 2 0 -0.0003 8 0 0 0 2.26E+07 1.73E+07 - - - 4.7263 0.9909 221125_WJC_METTL3_EV_vs_WT_F04.12553.12553.2 2.66E-05 26-Oct R.SSGPYGGGGQYFAK.P "sp|Q32P51|RA1L2_HUMAN,sp|P09651|ROA1_HUMAN,tr|A0A7I2YQX9|A0A7I2YQX9_HUMAN,tr|A0A7I2V5N7|A0A7I2V5N7_HUMAN,tr|A0A7I2V661|A0A7I2V661_HUMAN,tr|A0A7I2V520|A0A7I2V520_HUMAN,tr|A0A7I2V2F1|A0A7I2V2F1_HUMAN,tr|A0A7I2V497|A0A7I2V497_HUMAN,tr|A0A7I2V3K5|A0A7I2V3K5_HUMAN,tr|A0A7I2V2M7|A0A7I2V2M7_HUMAN,tr|A0A7I2V4P7|A0A7I2V4P7_HUMAN,tr|A0A7I2V5P1|A0A7I2V5P1_HUMAN,tr|A0A7I2V334|A0A7I2V334_HUMAN,tr|A0A7I2V4E2|A0A7I2V4E2_HUMAN,tr|A0A7I2V4F8|A0A7I2V4F8_HUMAN,tr|A0A7I2V3R8|A0A7I2V3R8_HUMAN,tr|F8W6I7|F8W6I7_HUMAN,tr|A0A7I2V666|A0A7I2V666_HUMAN,tr|A0A7I2V2Q7|A0A7I2V2Q7_HUMAN,tr|A0A7I2V459|A0A7I2V459_HUMAN,tr|A0A7I2YQY2|A0A7I2YQY2_HUMAN,tr|H0YH80|H0YH80_HUMAN,tr|A0A7I2V3W0|A0A7I2V3W0_HUMAN,tr|A0A7I2V3U8|A0A7I2V3U8_HUMAN,tr|A0A7I2V2R4|A0A7I2V2R4_HUMAN,tr|A0A7I2V2X1|A0A7I2V2X1_HUMAN,tr|A0A7I2V453|A0A7I2V453_HUMAN,tr|A0A7I2V360|A0A7I2V360_HUMAN" 28 1374.6204 1.07 46790 12553 2 1374.619352 688.3175 Heterogeneous nuclear ribonucleoprotein A1-like 2 OS=Homo sapiens OX=9606 GN=HNRNPA1L2 PE=2 SV=2 8.22 2449.3 - 1.81E+06 - - - -0.7842 - 1.979 0.524 - 263.7 1 1 0 -0.0011 14 0 0 0 6.56E+07 6.13E+07 - - - 4.6239 0.9991 221125_WJC_METTL3_EV_vs_WT_F04.12555.12555.3 0.00606 Oct-36 R.R[166.11]IDISPSTLR[166.11].K "sp|Q9NYF8|BCLF1_HUMAN,tr|E9PKI6|E9PKI6_HUMAN,tr|A0A1W2PQ43|A0A1W2PQ43_HUMAN,tr|E9PK91|E9PK91_HUMAN,tr|E9PK09|E9PK09_HUMAN,tr|E9PQN2|E9PQN2_HUMAN" 6 1176.673 2.09 46792 12555 3 1176.670433 393.2316 Bcl-2-associated transcription factor 1 OS=Homo sapiens OX=9606 GN=BCLAF1 PE=1 SV=2 9.6 2449.4 - 2.30E+06 - - - -2.1484 - 1.837 0.322 - 101.4 1 2 0 -0.0025 10 0 0 0 9.68E+07 4.63E+07 - - - 3.9053 0.9997 221125_WJC_METTL3_EV_vs_WT_F04.12556.12556.2 0.000209 20-Sep K.QQLEAVNEAIK[136.11].S sp|O95347|SMC2_HUMAN 1 1249.6758 1.04 46793 12556 2 1249.674995 625.8452 Structural maintenance of chromosomes protein 2 OS=Homo sapiens OX=9606 GN=SMC2 PE=1 SV=2 4.53 2449.5 - 1.22E+06 - - - -0.617 - 1.919 0.406 - 312.9 1 2 0 -0.0008 11 0 0 0 8.92E+06 8.56E+06 - - - 3.8028 0.9996 221125_WJC_METTL3_EV_vs_WT_F04.12557.12557.2 0.00167 18-Dec R.R[166.11]IDISPSTLR[166.11].K "sp|Q9NYF8|BCLF1_HUMAN,tr|E9PKI6|E9PKI6_HUMAN,tr|A0A1W2PQ43|A0A1W2PQ43_HUMAN,tr|E9PK91|E9PK91_HUMAN,tr|E9PK09|E9PK09_HUMAN,tr|E9PQN2|E9PQN2_HUMAN" 6 1176.673 2.04 46794 12557 2 1176.671107 589.3438 Bcl-2-associated transcription factor 1 OS=Homo sapiens OX=9606 GN=BCLAF1 PE=1 SV=2 9.6 2449.6 - 1.01E+06 - - - -1.5756 - 2.124 0.346 - 238.8 1 2 0 -0.0019 10 0 0 0 5.17E+07 2.54E+07 - - - 3.6987 0.9995 221125_WJC_METTL3_EV_vs_WT_F04.12558.12558.2 0.0291 20-Oct R.NSSISGPFGSR.S "sp|Q13610|PWP1_HUMAN,tr|B4DJV5|B4DJV5_HUMAN" 2 1107.5309 1.09 46795 12558 2 1107.532388 554.7727 Periodic tryptophan protein 1 homolog OS=Homo sapiens OX=9606 GN=PWP1 PE=1 SV=1 9.75 2449.7 - 758372 - - - 1.3562 - 1.884 0.368 - 244.2 1 2 0 0.0015 11 0 0 0 1.10E+07 1.02E+07 - - - 3.4721 0.9998 221125_WJC_METTL3_EV_vs_WT_F04.12559.12559.3 0.0156 Dec-44 R.YSALNVQHQMLK.S "sp|O00461|GOLI4_HUMAN,tr|F8W785|F8W785_HUMAN" 2 1430.734 0.92 46796 12559 3 1430.733035 477.9186 Golgi integral membrane protein 4 OS=Homo sapiens OX=9606 GN=GOLIM4 PE=1 SV=1 8.6 2449.9 - 751147 - - - -0.6885 - 2.111 0.366 - 104.7 1 2 0 -0.001 12 0 0 0 1.08E+07 1.18E+07 - - - 4.6913 0.9992 221125_WJC_METTL3_EV_vs_WT_F04.12560.12560.2 0.000777 22-Dec R.VITVDGNIC[160.03]TGK[136.11].G "sp|O95299|NDUAA_HUMAN,tr|A0A7I2V4N8|A0A7I2V4N8_HUMAN,tr|A0A7I2V2N6|A0A7I2V2N6_HUMAN,tr|H7C1Y7|H7C1Y7_HUMAN,tr|A0A7I2V5B2|A0A7I2V5B2_HUMAN,tr|A0A7I2V419|A0A7I2V419_HUMAN,tr|A0A7I2V2W9|A0A7I2V2W9_HUMAN,tr|A0A7I2V2X3|A0A7I2V2X3_HUMAN,tr|A0A7I2YQU0|A0A7I2YQU0_HUMAN,tr|H7C2X4|H7C2X4_HUMAN,tr|A0A7I2V438|A0A7I2V438_HUMAN,tr|Q8N1B9|Q8N1B9_HUMAN,tr|A0A7I2V2J5|A0A7I2V2J5_HUMAN,tr|E7ESZ7|E7ESZ7_HUMAN,tr|C9J6X0|C9J6X0_HUMAN,tr|A0A7I2V3H5|A0A7I2V3H5_HUMAN,tr|A0A7I2V5L0|A0A7I2V5L0_HUMAN,tr|A0A087WXC5|A0A087WXC5_HUMAN,tr|A0A7I2V458|A0A7I2V458_HUMAN,tr|A0A7I2V2F6|A0A7I2V2F6_HUMAN,tr|A0A7I2V594|A0A7I2V594_HUMAN,tr|A0A7I2V327|A0A7I2V327_HUMAN,tr|A0A7I2V5U7|A0A7I2V5U7_HUMAN,tr|A0A7I2V3D4|A0A7I2V3D4_HUMAN,tr|A0A7I2V2I6|A0A7I2V2I6_HUMAN" 25 1283.6635 2.13 46797 12560 2 1283.659903 642.839 "NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 10, mitochondrial OS=Homo sapiens OX=9606 GN=NDUFA10 PE=1 SV=1" 5.8 2450 - 657137 - - - -2.792 - 2.014 0.437 - 377.3 1 2 0 -0.0036 12 0 0 0 8.99E+06 4.22E+06 - - - 4.1097 1 221125_WJC_METTL3_EV_vs_WT_F04.12562.12562.3 2.04E-07 17/52 K.IYYHVVETGSMGAR[166.11].L sp|Q99805|TM9S2_HUMAN 1 1591.7692 1.34 46799 12562 3 1591.766517 531.597 Transmembrane 9 superfamily member 2 OS=Homo sapiens OX=9606 GN=TM9SF2 PE=1 SV=1 6.75 2450.2 - 610092 - - - -1.7063 - 3.08 0.537 - 516.7 1 2 0 -0.0027 14 0 0 0 1.44E+07 1.08E+07 - - - 7.5158 0.9993 221125_WJC_METTL3_EV_vs_WT_F04.12564.12564.2 0.0939 24-Dec R.LQTQASATVAIPK[136.11].E "sp|Q00341|VIGLN_HUMAN,tr|C9JZI8|C9JZI8_HUMAN,tr|A0A024R4E5|A0A024R4E5_HUMAN,tr|C9JIZ1|C9JIZ1_HUMAN,tr|H7C0A4|H7C0A4_HUMAN,tr|H0Y394|H0Y394_HUMAN,tr|C9J5E5|C9J5E5_HUMAN" 7 1334.7649 1.39 46801 12564 2 1334.762105 668.3897 Vigilin OS=Homo sapiens OX=9606 GN=HDLBP PE=1 SV=2 8.75 2450.5 - 524240 - - - -2.106 - 2.202 0.339 - 393 1 2 0 -0.0028 13 0 0 0 1.27E+07 9.14E+06 - - - 3.5699 0.9997 221125_WJC_METTL3_EV_vs_WT_F04.12565.12565.2 3.02E-06 24-Dec R.LQTQASATVAIPK.E "sp|Q00341|VIGLN_HUMAN,tr|C9JZI8|C9JZI8_HUMAN,tr|A0A024R4E5|A0A024R4E5_HUMAN,tr|C9JIZ1|C9JIZ1_HUMAN,tr|H7C0A4|H7C0A4_HUMAN,tr|H0Y394|H0Y394_HUMAN,tr|C9J5E5|C9J5E5_HUMAN" 7 1326.7507 1.39 46802 12565 2 1326.748941 664.3826 Vigilin OS=Homo sapiens OX=9606 GN=HDLBP PE=1 SV=2 8.75 2450.6 - 504711 - - - -1.3379 - 2.558 0.368 - 425.1 1 2 0 -0.0018 13 0 0 0 1.27E+07 9.14E+06 - - - 4.169 1 221125_WJC_METTL3_EV_vs_WT_F04.12566.12566.2 1.07E-10 13/22 K.NDFTEEEEAQVR[166.11].K "sp|P63208|SKP1_HUMAN,tr|E5RJR5|E5RJR5_HUMAN" 2 1475.6404 0.8 46803 12566 2 1475.639634 738.8275 S-phase kinase-associated protein 1 OS=Homo sapiens OX=9606 GN=SKP1 PE=1 SV=2 3.91 2450.7 - 450241 - - - -0.5103 - 2.745 0.738 - 867.4 1 2 0 -0.0008 12 0 0 0 3.24E+07 4.05E+07 - - - 7.1485 1 221125_WJC_METTL3_EV_vs_WT_F04.12568.12568.2 6.81E-09 14/22 K.FDETEQALANER.K "sp|Q7L014|DDX46_HUMAN,tr|A0A0C4DG89|A0A0C4DG89_HUMAN" 2 1421.6423 2.99 46805 12568 2 1421.640604 711.8284 Probable ATP-dependent RNA helicase DDX46 OS=Homo sapiens OX=9606 GN=DDX46 PE=1 SV=2 4 2451 - 220697 - - - -1.1838 - 2.783 0.661 - 935.9 1 2 0 -0.0017 12 0 0 0 1.10E+07 3.68E+06 - - - 6.6157 0.9999 221125_WJC_METTL3_EV_vs_WT_F04.12570.12570.2 6.92E-06 20-Oct K.EVFGDDSEISK.E sp|O43395|PRPF3_HUMAN 1 1224.551 1.35 46806 12570 2 1224.550275 613.2828 U4\U6 small nuclear ribonucleoprotein Prp3 OS=Homo sapiens OX=9606 GN=PRPF3 PE=1 SV=2 3.92 2451.2 - 1.02E+07 - - - -0.6027 - 1.903 0.56 - 259.5 1 2 0 -0.0007 11 0 0 0 1.30E+08 9.56E+07 - - - 4.9176 0.9998 221125_WJC_METTL3_EV_vs_WT_F04.12571.12571.2 0.0127 20-Oct K.TYNEPGSQVFK.D "sp|Q86U86|PB1_HUMAN,tr|H0Y5B5|H0Y5B5_HUMAN,tr|E7EVG2|E7EVG2_HUMAN" 3 1268.6037 1.6 46807 12571 2 1268.6027 635.3091 Protein polybromo-1 OS=Homo sapiens OX=9606 GN=PBRM1 PE=1 SV=1 5.66 2451.3 - 1.65E+06 - - - -0.8017 - 1.806 0.486 - 239.9 1 2 0 -0.001 11 0 0 0 3.05E+07 1.91E+07 - - - 4.2294 0.9923 221125_WJC_METTL3_EV_vs_WT_F04.12572.12572.2 9.14E-08 26-Nov R.SSGPYGGGGQYFAK[136.11].P "sp|Q32P51|RA1L2_HUMAN,sp|P09651|ROA1_HUMAN,tr|A0A7I2YQX9|A0A7I2YQX9_HUMAN,tr|A0A7I2V5N7|A0A7I2V5N7_HUMAN,tr|A0A7I2V661|A0A7I2V661_HUMAN,tr|A0A7I2V520|A0A7I2V520_HUMAN,tr|A0A7I2V2F1|A0A7I2V2F1_HUMAN,tr|A0A7I2V497|A0A7I2V497_HUMAN,tr|A0A7I2V3K5|A0A7I2V3K5_HUMAN,tr|A0A7I2V2M7|A0A7I2V2M7_HUMAN,tr|A0A7I2V4P7|A0A7I2V4P7_HUMAN,tr|A0A7I2V5P1|A0A7I2V5P1_HUMAN,tr|A0A7I2V334|A0A7I2V334_HUMAN,tr|A0A7I2V4E2|A0A7I2V4E2_HUMAN,tr|A0A7I2V4F8|A0A7I2V4F8_HUMAN,tr|A0A7I2V3R8|A0A7I2V3R8_HUMAN,tr|F8W6I7|F8W6I7_HUMAN,tr|A0A7I2V666|A0A7I2V666_HUMAN,tr|A0A7I2V2Q7|A0A7I2V2Q7_HUMAN,tr|A0A7I2V459|A0A7I2V459_HUMAN,tr|A0A7I2YQY2|A0A7I2YQY2_HUMAN,tr|H0YH80|H0YH80_HUMAN,tr|A0A7I2V3W0|A0A7I2V3W0_HUMAN,tr|A0A7I2V3U8|A0A7I2V3U8_HUMAN,tr|A0A7I2V2R4|A0A7I2V2R4_HUMAN,tr|A0A7I2V2X1|A0A7I2V2X1_HUMAN,tr|A0A7I2V453|A0A7I2V453_HUMAN,tr|A0A7I2V360|A0A7I2V360_HUMAN" 28 1382.6346 1.21 46808 12572 2 1382.632765 692.3246 Heterogeneous nuclear ribonucleoprotein A1-like 2 OS=Homo sapiens OX=9606 GN=HNRNPA1L2 PE=2 SV=2 8.22 2451.4 - 2.91E+06 - - - -1.3489 - 2.212 0.595 - 258.6 1 1 0 -0.0019 14 0 0 0 6.41E+07 5.28E+07 - - - 5.4273 0.9999 221125_WJC_METTL3_EV_vs_WT_F04.12573.12573.3 0.000299 15/36 R.SLHDALC[160.03]VVK.R "sp|P17987|TCPA_HUMAN,tr|F5GZ03|F5GZ03_HUMAN,tr|F5H282|F5H282_HUMAN,tr|E7EQR6|E7EQR6_HUMAN,tr|E7ERF2|E7ERF2_HUMAN" 5 1140.5961 0.41 46809 12573 3 1140.594589 381.206 T-complex protein 1 subunit alpha OS=Homo sapiens OX=9606 GN=TCP1 PE=1 SV=1 6.46 2451.4 - 2.39E+06 - - - -1.3502 - 2.377 0.377 - 312.2 1 2 0 -0.0015 10 0 0 0 1.41E+08 3.44E+08 - - - 5.2714 1 221125_WJC_METTL3_EV_vs_WT_F04.12574.12574.3 1.73E-07 19/40 R.FPGQLNADLR[166.11]K[136.11].L "sp|P04350|TBB4A_HUMAN,sp|Q9BVA1|TBB2B_HUMAN,sp|A6NNZ2|TBB8B_HUMAN,sp|P07437|TBB5_HUMAN,sp|Q13509|TBB3_HUMAN,sp|Q13885|TBB2A_HUMAN,sp|P68371|TBB4B_HUMAN,sp|Q9BUF5|TBB6_HUMAN,sp|Q3ZCM7|TBB8_HUMAN,sp|Q9H4B7|TBB1_HUMAN,tr|M0R2D3|M0R2D3_HUMAN,tr|A0A0B4J269|A0A0B4J269_HUMAN,tr|Q5ST81|Q5ST81_HUMAN,tr|Q5JP53|Q5JP53_HUMAN,tr|K7ESM5|K7ESM5_HUMAN,tr|A0A075B736|A0A075B736_HUMAN,tr|G3V2A3|G3V2A3_HUMAN,tr|Q5SQY0|Q5SQY0_HUMAN" 18 1275.7054 0.44 46810 12574 3 1275.704567 426.2424 Tubulin beta-4A chain OS=Homo sapiens OX=9606 GN=TUBB4A PE=1 SV=2 8.75 2451.5 - 2.15E+06 - - - -0.6843 - 2.924 0.551 - 404.9 1 2 0 -0.0009 11 0 0 0 1.59E+07 3.58E+07 - - - 7.7309 1 221125_WJC_METTL3_EV_vs_WT_F04.12575.12575.2 3.65E-09 13/22 K.NDFTEEEEAQVR.K "sp|P63208|SKP1_HUMAN,tr|E5RJR5|E5RJR5_HUMAN" 2 1465.6321 0.8 46811 12575 2 1465.629304 733.8233 S-phase kinase-associated protein 1 OS=Homo sapiens OX=9606 GN=SKP1 PE=1 SV=2 3.91 2451.6 - 1.14E+06 - - - -1.9193 - 2.65 0.618 - 757.1 1 2 0 -0.0028 12 0 0 0 3.24E+07 4.05E+07 - - - 6.1689 1 221125_WJC_METTL3_EV_vs_WT_F04.12576.12576.3 6.25E-06 13/44 R.YSALNVQHQMLK[136.11].S "sp|O00461|GOLI4_HUMAN,tr|F8W785|F8W785_HUMAN" 2 1438.7482 0.92 46812 12576 3 1438.746875 480.59 Golgi integral membrane protein 4 OS=Homo sapiens OX=9606 GN=GOLIM4 PE=1 SV=1 8.6 2451.7 - 1.03E+06 - - - -0.9348 - 2.416 0.503 - 112.8 1 2 0 -0.0013 12 0 0 0 1.08E+07 1.18E+07 - - - 6.5927 1 221125_WJC_METTL3_EV_vs_WT_F04.12577.12577.3 1.54E-06 15/52 R.FVPAEMGTHTVSVK.Y "sp|P21333|FLNA_HUMAN,tr|A0A7P0NMY4|A0A7P0NMY4_HUMAN,tr|Q60FE5|Q60FE5_HUMAN,tr|H0Y5C6|H0Y5C6_HUMAN" 4 1501.7599 1.13 46813 12577 3 1501.762641 501.5939 Filamin-A OS=Homo sapiens OX=9606 GN=FLNA PE=1 SV=4 6.75 2451.8 - 788972 - - - 1.8252 - 3.07 0.572 - 172.4 1 2 0 0.0027 14 0 0 0 6.05E+06 5.35E+06 - - - 7.8974 0.978 221125_WJC_METTL3_EV_vs_WT_F04.12578.12578.2 0.831 20-Oct K.ASLENSLEETK.G "sp|P02533|K1C14_HUMAN,sp|P08779|K1C16_HUMAN,tr|K7ENW6|K7ENW6_HUMAN" 3 1219.5932 32.14 46814 12578 2 1219.597199 610.8039 "Keratin, type I cytoskeletal 14 OS=Homo sapiens OX=9606 GN=KRT14 PE=1 SV=4" 4.25 2452 - 689475 - - - 3.2691 - 1.946 0.057 - 223.5 1 2 0 0.004 11 0 0 0 1.92E+07 5.98E+05 - - - 1.2618 0.9999 221125_WJC_METTL3_EV_vs_WT_F04.12579.12579.3 0.000185 15/40 K.VGKFPFAANSR.A "sp|P09622|DLDH_HUMAN,tr|E9PEX6|E9PEX6_HUMAN" 2 1192.6353 1.29 46815 12579 3 1192.636077 398.5524 "Dihydrolipoyl dehydrogenase, mitochondrial OS=Homo sapiens OX=9606 GN=DLD PE=1 SV=2" 11 2452.1 - 585644 - - - 0.6582 - 2.509 0.496 - 323.6 1 2 1 0.0008 11 0 0 0 5.95E+06 4.62E+06 - - - 6.6829 0.9994 221125_WJC_METTL3_EV_vs_WT_F04.12580.12580.3 0.00229 Oct-48 R.VKPFMTGAAEQIK.H "sp|P13693|TCTP_HUMAN,sp|Q56UQ5|TPT1L_HUMAN,tr|Q5W0H4|Q5W0H4_HUMAN,tr|A0A0B4J2C3|A0A0B4J2C3_HUMAN,tr|J3KPG2|J3KPG2_HUMAN,tr|E9PJF7|E9PJF7_HUMAN" 6 1418.7592 1.43 46816 12580 3 1418.759954 473.927 Translationally-controlled tumor protein OS=Homo sapiens OX=9606 GN=TPT1 PE=1 SV=1 8.56 2452.2 - 462336 - - - 0.5512 - 1.834 0.315 - 107.5 1 2 0 0.0008 13 0 0 0 8.90E+06 6.23E+06 - - - 3.6961 0.9979 221125_WJC_METTL3_EV_vs_WT_F04.12581.12581.3 0.00119 13/40 K.VGK[136.11]FPFAANSR[166.11].A "sp|P09622|DLDH_HUMAN,tr|E9PEX6|E9PEX6_HUMAN" 2 1210.6578 1.69 46817 12581 3 1210.656843 404.5599 "Dihydrolipoyl dehydrogenase, mitochondrial OS=Homo sapiens OX=9606 GN=DLD PE=1 SV=2" 11 2452.4 - 415122 - - - -0.7591 - 2.189 0.279 - 209.5 1 2 1 -0.0009 11 0 0 0 5.94E+06 3.51E+06 - - - 3.876 0.9995 221125_WJC_METTL3_EV_vs_WT_F04.12582.12582.2 0.0038 18-Oct R.QLQEYLAQGK[136.11].A sp|Q587I9|SFT2C_HUMAN 1 1184.6281 0.97 46818 12582 2 1184.626509 593.3213 Vesicle transport protein SFT2C OS=Homo sapiens OX=9606 GN=SFT2D3 PE=2 SV=1 6 2452.5 - 374228 - - - -1.3329 - 1.821 0.353 - 311.6 1 2 0 -0.0016 10 0 0 0 1.09E+07 1.12E+07 - - - 3.3208 0.9996 221125_WJC_METTL3_EV_vs_WT_F04.12583.12583.2 0.00132 Jul-32 R.QVVAVTGDGTNDGPALK[136.11].K "sp|Q01814|AT2B2_HUMAN,sp|P20020|AT2B1_HUMAN,sp|Q16720|AT2B3_HUMAN,sp|P23634|AT2B4_HUMAN,tr|A0A804HKZ0|A0A804HKZ0_HUMAN,tr|E7ERY9|E7ERY9_HUMAN,tr|A0A2R8Y4R4|A0A2R8Y4R4_HUMAN,tr|A0A2U3TZI3|A0A2U3TZI3_HUMAN,tr|A0A2U3U055|A0A2U3U055_HUMAN" 9 1648.8512 -1 46819 12583 2 1648.848718 825.4329 Plasma membrane calcium-transporting ATPase 2 OS=Homo sapiens OX=9606 GN=ATP2B2 PE=1 SV=2 4.21 2452.6 - 207908 - - - -1.4835 - 1.775 0.45 - 122.2 1 2 0 -0.0024 17 0 0 0 0.00E+00 0.00E+00 - - - 3.7746 0.9998 221125_WJC_METTL3_EV_vs_WT_F04.12586.12586.3 0.00136 14/36 R.RIDISPSTLR.K "sp|Q9NYF8|BCLF1_HUMAN,tr|E9PKI6|E9PKI6_HUMAN,tr|A0A1W2PQ43|A0A1W2PQ43_HUMAN,tr|E9PK91|E9PK91_HUMAN,tr|E9PK09|E9PK09_HUMAN,tr|E9PQN2|E9PQN2_HUMAN" 6 1156.6564 2.08 46821 12586 3 1156.655368 386.5594 Bcl-2-associated transcription factor 1 OS=Homo sapiens OX=9606 GN=BCLAF1 PE=1 SV=2 9.6 2453 - 6.36E+06 - - - -0.9104 - 2.34 0.316 - 427.9 1 2 0 -0.0011 10 0 0 0 9.68E+07 4.65E+07 - - - 4.5456 1 221125_WJC_METTL3_EV_vs_WT_F04.12587.12587.2 5.36E-06 22-Dec R.ISVYYNEATGGK[136.11].Y "sp|P07437|TBB5_HUMAN,tr|Q5JP53|Q5JP53_HUMAN" 2 1308.6441 0.64 46822 12587 2 1308.64262 655.3293 Tubulin beta chain OS=Homo sapiens OX=9606 GN=TUBB PE=1 SV=2 6 2453 - 5.48E+06 - - - -1.1554 - 2.487 0.619 - 686.1 1 2 0 -0.0015 12 0 0 0 1.22E+08 1.91E+08 - - - 6.0097 0.9999 221125_WJC_METTL3_EV_vs_WT_F04.12588.12588.3 0.000657 13/36 R.SLHDALC[160.03]VVK[136.11].R "sp|P17987|TCPA_HUMAN,tr|F5GZ03|F5GZ03_HUMAN,tr|F5H282|F5H282_HUMAN,tr|E7EQR6|E7EQR6_HUMAN,tr|E7ERF2|E7ERF2_HUMAN" 5 1148.6103 0.41 46823 12588 3 1148.608259 383.8774 T-complex protein 1 subunit alpha OS=Homo sapiens OX=9606 GN=TCP1 PE=1 SV=1 6.46 2453.1 - 1.83E+07 - - - -1.8022 - 2.195 0.477 - 289.4 1 2 0 -0.0021 10 0 0 0 1.41E+08 3.44E+08 - - - 6.1535 1 221125_WJC_METTL3_EV_vs_WT_F04.12589.12589.3 1.78E-08 17/52 K.IYYHVVETGSMGAR.L sp|Q99805|TM9S2_HUMAN 1 1581.761 1.34 46824 12589 3 1581.761108 528.2609 Transmembrane 9 superfamily member 2 OS=Homo sapiens OX=9606 GN=TM9SF2 PE=1 SV=1 6.75 2453.1 - 1.73E+06 - - - 0.0917 - 3.042 0.624 - 483.1 1 2 0 0.0001 14 0 0 0 1.44E+07 1.08E+07 - - - 8.4535 0.9999 221125_WJC_METTL3_EV_vs_WT_F04.12590.12590.2 3.57E-08 22-Nov R.VITVDGNIC[160.03]TGK.G "sp|O95299|NDUAA_HUMAN,tr|A0A7I2V4N8|A0A7I2V4N8_HUMAN,tr|A0A7I2V2N6|A0A7I2V2N6_HUMAN,tr|H7C1Y7|H7C1Y7_HUMAN,tr|A0A7I2V5B2|A0A7I2V5B2_HUMAN,tr|A0A7I2V419|A0A7I2V419_HUMAN,tr|A0A7I2V2W9|A0A7I2V2W9_HUMAN,tr|A0A7I2V2X3|A0A7I2V2X3_HUMAN,tr|A0A7I2YQU0|A0A7I2YQU0_HUMAN,tr|H7C2X4|H7C2X4_HUMAN,tr|A0A7I2V438|A0A7I2V438_HUMAN,tr|Q8N1B9|Q8N1B9_HUMAN,tr|A0A7I2V2J5|A0A7I2V2J5_HUMAN,tr|E7ESZ7|E7ESZ7_HUMAN,tr|C9J6X0|C9J6X0_HUMAN,tr|A0A7I2V3H5|A0A7I2V3H5_HUMAN,tr|A0A7I2V5L0|A0A7I2V5L0_HUMAN,tr|A0A087WXC5|A0A087WXC5_HUMAN,tr|A0A7I2V458|A0A7I2V458_HUMAN,tr|A0A7I2V2F6|A0A7I2V2F6_HUMAN,tr|A0A7I2V594|A0A7I2V594_HUMAN,tr|A0A7I2V327|A0A7I2V327_HUMAN,tr|A0A7I2V5U7|A0A7I2V5U7_HUMAN,tr|A0A7I2V3D4|A0A7I2V3D4_HUMAN,tr|A0A7I2V2I6|A0A7I2V2I6_HUMAN" 25 1275.6493 2.13 46825 12590 2 1275.649742 638.8319 "NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 10, mitochondrial OS=Homo sapiens OX=9606 GN=NDUFA10 PE=1 SV=1" 5.8 2453.2 - 1.71E+06 - - - 0.3567 - 2.177 0.538 - 366.5 1 2 0 0.0005 12 0 0 0 8.99E+06 4.22E+06 - - - 5.0614 1 221125_WJC_METTL3_EV_vs_WT_F04.12592.12592.3 3.29E-06 13/44 K.NDFTEEEEAQVR[166.11].K "sp|P63208|SKP1_HUMAN,tr|E5RJR5|E5RJR5_HUMAN" 2 1475.6404 0.82 46827 12592 3 1475.641647 492.8874 S-phase kinase-associated protein 1 OS=Homo sapiens OX=9606 GN=SKP1 PE=1 SV=2 3.91 2453.4 - 990536 - - - 0.8539 - 2.392 0.482 - 302 1 2 0 0.0013 12 0 0 0 6.98E+06 8.50E+06 - - - 6.3309 0.9998 221125_WJC_METTL3_EV_vs_WT_F04.12594.12594.3 0.000386 Oct-44 R.AQVQEFC[160.03]DYGTK[136.11].E "sp|Q86U44|MTA70_HUMAN,tr|H0YFV6|H0YFV6_HUMAN" 2 1452.6435 0.001 46829 12594 3 1452.641329 485.2218 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 4.37 2453.6 - 748963 - - - -1.4807 - 1.758 0.427 - 114 1 2 0 -0.0022 12 0 0 0 0.00E+00 3.26E+06 - - - 4.8638 1 221125_WJC_METTL3_EV_vs_WT_F04.12595.12595.3 1.07E-06 Dec-44 K.NDFTEEEEAQVR.K "sp|P63208|SKP1_HUMAN,tr|E5RJR5|E5RJR5_HUMAN" 2 1465.6321 0.83 46830 12595 3 1465.631936 489.5513 S-phase kinase-associated protein 1 OS=Homo sapiens OX=9606 GN=SKP1 PE=1 SV=2 3.91 2453.8 - 592626 - - - -0.1235 - 2.397 0.629 - 277.6 1 2 0 -0.0002 12 0 0 0 7.06E+06 8.50E+06 - - - 7.9759 0.9893 221125_WJC_METTL3_EV_vs_WT_F04.12598.12598.2 0.0626 16-Jun R.HPNFLVVEK.D sp|Q16864|VATF_HUMAN 1 1081.592 3.25 46833 12598 2 1081.588938 541.8033 V-type proton ATPase subunit F OS=Homo sapiens OX=9606 GN=ATP6V1F PE=1 SV=2 6.75 2454.1 - 344975 - - - -2.8587 - 1.326 0.231 - 98.1 1 2 0 -0.0031 9 0 0 0 5.38E+06 1.66E+06 - - - 1.5625 0.9997 221125_WJC_METTL3_EV_vs_WT_F04.12600.12600.2 0.00115 24-Aug K.ITESVAETAQTIK[136.11].K sp|Q96A49|SYAP1_HUMAN 1 1397.7493 1.44 46835 12600 2 1397.749551 699.8819 Synapse-associated protein 1 OS=Homo sapiens OX=9606 GN=SYAP1 PE=1 SV=1 4.53 2454.4 - 221171 - - - 0.1617 - 2.146 0.346 - 168.5 1 2 0 0.0002 13 0 0 0 5.28E+06 3.66E+06 - - - 3.5563 0.9999 221125_WJC_METTL3_EV_vs_WT_F04.12604.12604.3 0.00788 13/52 K.VDEAVAVLQAHQAK.E "sp|Q9H361|PABP3_HUMAN,sp|P11940|PABP1_HUMAN,tr|H0YAS6|H0YAS6_HUMAN,tr|H0YB75|H0YB75_HUMAN,tr|H0YAS7|H0YAS7_HUMAN,tr|A0A7I2YQE4|A0A7I2YQE4_HUMAN,tr|A0A7I2V649|A0A7I2V649_HUMAN,tr|H0YC10|H0YC10_HUMAN,tr|H0YAR2|H0YAR2_HUMAN,tr|E7ERJ7|E7ERJ7_HUMAN,tr|A0A7I2YQ88|A0A7I2YQ88_HUMAN,tr|A0A087WTT1|A0A087WTT1_HUMAN,tr|A0A7I2YQ90|A0A7I2YQ90_HUMAN,tr|A0A7I2V4N4|A0A7I2V4N4_HUMAN,tr|E7EQV3|E7EQV3_HUMAN" 15 1477.7889 1.33 46837 12604 3 1477.787826 493.6036 Polyadenylate-binding protein 3 OS=Homo sapiens OX=9606 GN=PABPC3 PE=1 SV=2 5.32 2454.8 - 2.99E+06 - - - -0.7213 - 2.647 0.36 - 261.7 1 2 0 -0.0011 14 0 0 0 1.15E+08 8.64E+07 - - - 5.1403 1 221125_WJC_METTL3_EV_vs_WT_F04.12605.12605.3 1.09E-05 13/52 K.VDEAVAVLQAHQAK[136.11].E "sp|Q9H361|PABP3_HUMAN,sp|P11940|PABP1_HUMAN,tr|H0YAS6|H0YAS6_HUMAN,tr|H0YB75|H0YB75_HUMAN,tr|H0YAS7|H0YAS7_HUMAN,tr|A0A7I2YQE4|A0A7I2YQE4_HUMAN,tr|A0A7I2V649|A0A7I2V649_HUMAN,tr|H0YC10|H0YC10_HUMAN,tr|H0YAR2|H0YAR2_HUMAN,tr|E7ERJ7|E7ERJ7_HUMAN,tr|A0A7I2YQ88|A0A7I2YQ88_HUMAN,tr|A0A087WTT1|A0A087WTT1_HUMAN,tr|A0A7I2YQ90|A0A7I2YQ90_HUMAN,tr|A0A7I2V4N4|A0A7I2V4N4_HUMAN,tr|E7EQV3|E7EQV3_HUMAN" 15 1485.8031 1.32 46838 12605 3 1485.801204 496.275 Polyadenylate-binding protein 3 OS=Homo sapiens OX=9606 GN=PABPC3 PE=1 SV=2 5.32 2454.9 - 2.12E+06 - - - -1.2707 - 2.355 0.529 - 257.2 1 2 0 -0.0019 14 0 0 0 1.15E+08 8.68E+07 - - - 6.7136 0.8233 221125_WJC_METTL3_EV_vs_WT_F04.12606.12606.3 0.345 Aug-40 R.LYHDIAQQAFK.F sp|Q14152|EIF3A_HUMAN 1 1332.6826 1.79 46839 12606 3 1332.683394 445.2348 Eukaryotic translation initiation factor 3 subunit A OS=Homo sapiens OX=9606 GN=EIF3A PE=1 SV=1 6.74 2455 - 1.73E+06 - - - 0.5688 - 1.389 0.068 - 76.3 2 2 0 0.0008 11 0 0 0 1.40E+07 7.84E+06 - - - 0.0921 0.9991 221125_WJC_METTL3_EV_vs_WT_F04.12607.12607.2 2.05E-06 20-Dec K.EAAFDDAVEER.V "sp|Q09028|RBBP4_HUMAN,tr|E9PIC4|E9PIC4_HUMAN,tr|E9PNS2|E9PNS2_HUMAN,tr|E9PNS6|E9PNS6_HUMAN" 4 1250.5415 2.8 46840 12607 2 1250.536241 626.278 Histone-binding protein RBBP4 OS=Homo sapiens OX=9606 GN=RBBP4 PE=1 SV=3 3.83 2455 - 1.64E+06 - - - -4.2142 - 2.419 0.579 - 554.4 1 2 0 -0.0053 11 0 0 0 1.38E+07 4.94E+06 - - - 5.7055 0.9999 221125_WJC_METTL3_EV_vs_WT_F04.12609.12609.3 0.000287 Dec-44 K.DLHDANTDLIGR[166.11].H "sp|P53985|MOT1_HUMAN,tr|Q5T8R3|Q5T8R3_HUMAN,tr|Q5T8R5|Q5T8R5_HUMAN" 3 1348.6611 1.54 46842 12609 3 1348.659598 450.561 Monocarboxylate transporter 1 OS=Homo sapiens OX=9606 GN=SLC16A1 PE=1 SV=3 4.41 2455.2 - 1.30E+06 - - - -1.0855 - 2.243 0.405 - 253.8 1 2 0 -0.0015 12 0 0 0 1.60E+07 1.04E+07 - - - 5.2941 0.9999 221125_WJC_METTL3_EV_vs_WT_F04.12610.12610.2 1.64E-05 16-Sep R.NVDFNYATK[136.11].D "sp|Q8WWM7|ATX2L_HUMAN,tr|H3BSQ5|H3BSQ5_HUMAN,tr|H3BSK9|H3BSK9_HUMAN,tr|H3BUE3|H3BUE3_HUMAN,tr|H3BUF6|H3BUF6_HUMAN" 5 1078.5175 1.26 46843 12610 2 1078.517393 540.266 Ataxin-2-like protein OS=Homo sapiens OX=9606 GN=ATXN2L PE=1 SV=2 5.83 2455.3 - 1.20E+06 - - - -0.076 - 1.779 0.513 - 245.8 1 2 0 -0.0001 9 0 0 0 4.66E+07 3.68E+07 - - - 4.4965 0.9713 221125_WJC_METTL3_EV_vs_WT_F04.12611.12611.3 0.732 Oct-40 R.LYHDIAQQAFK[136.11].F sp|Q14152|EIF3A_HUMAN 1 1340.6968 1.79 46844 12611 3 1340.696651 447.9062 Eukaryotic translation initiation factor 3 subunit A OS=Homo sapiens OX=9606 GN=EIF3A PE=1 SV=1 6.74 2455.4 - 1.33E+06 - - - -0.138 - 1.557 0.124 - 126.8 1 2 0 -0.0002 11 0 0 0 1.40E+07 7.84E+06 - - - 1.1802 0.9992 221125_WJC_METTL3_EV_vs_WT_F04.12614.12614.2 0.00067 18-Nov R.YSLDPENPTK[136.11].S "sp|P18621|RL17_HUMAN,tr|A0A087WWH0|A0A087WWH0_HUMAN,tr|J3QS96|J3QS96_HUMAN,tr|J3QQT2|J3QQT2_HUMAN,tr|J3KSJ0|J3KSJ0_HUMAN,tr|A0A087WY81|A0A087WY81_HUMAN,tr|J3KRB3|J3KRB3_HUMAN,tr|J3KRX5|J3KRX5_HUMAN,tr|A0A087WXM6|A0A087WXM6_HUMAN,tr|A0A0A6YYL6|A0A0A6YYL6_HUMAN" 10 1170.5648 1.02 46847 12614 2 1170.561392 586.2897 60S ribosomal protein L17 OS=Homo sapiens OX=9606 GN=RPL17 PE=1 SV=3 4.37 2455.7 - 728133 - - - -2.9276 - 1.861 0.47 - 348.8 1 2 0 -0.0034 10 0 0 0 2.89E+08 2.84E+08 - - - 4.2451 0.9882 221125_WJC_METTL3_EV_vs_WT_F04.12615.12615.2 1.52E-05 20-Aug K.EAAFDDAVEER[166.11].V "sp|Q09028|RBBP4_HUMAN,tr|E9PIC4|E9PIC4_HUMAN,tr|E9PNS2|E9PNS2_HUMAN,tr|E9PNS6|E9PNS6_HUMAN" 4 1260.5498 2.85 46848 12615 2 1260.54054 631.2822 Histone-binding protein RBBP4 OS=Homo sapiens OX=9606 GN=RBBP4 PE=1 SV=3 3.83 2455.8 - 547276 - - - -7.3309 - 1.96 0.527 - 206.7 1 2 0 -0.0092 11 0 0 0 1.41E+07 4.94E+06 - - - 4.751 0.9998 221125_WJC_METTL3_EV_vs_WT_F04.12617.12617.3 2.73E-06 Dec-52 R.GLEATASPGLLK[136.11]PK[136.11].N "sp|Q9Y467|SALL2_HUMAN,tr|F5H433|F5H433_HUMAN,tr|E7EW59|E7EW59_HUMAN,tr|H0YFS7|H0YFS7_HUMAN" 4 1396.8261 1.42 46850 12617 3 1396.822174 466.616 Sal-like protein 2 OS=Homo sapiens OX=9606 GN=SALL2 PE=1 SV=4 8.59 2456.1 - 406713 - - - -2.7863 - 2.229 0.44 - 150.5 1 2 0 -0.0039 14 0 0 0 1.67E+07 1.18E+07 - - - 5.5746 1 221125_WJC_METTL3_EV_vs_WT_F04.12621.12621.3 3.27E-06 16/52 R.GLEATASPGLLKPK.N "sp|Q9Y467|SALL2_HUMAN,tr|F5H433|F5H433_HUMAN,tr|E7EW59|E7EW59_HUMAN,tr|H0YFS7|H0YFS7_HUMAN" 4 1380.7977 1.43 46853 12621 3 1380.797457 461.2732 Sal-like protein 2 OS=Homo sapiens OX=9606 GN=SALL2 PE=1 SV=4 8.59 2456.7 - 959253 - - - -0.1514 - 2.71 0.558 - 274.8 1 2 0 -0.0002 14 0 0 0 1.66E+07 1.16E+07 - - - 7.4105 0.9998 221125_WJC_METTL3_EV_vs_WT_F04.12623.12623.2 0.00111 16-Jul R.NVDFNYATK.D "sp|Q8WWM7|ATX2L_HUMAN,tr|H3BSQ5|H3BSQ5_HUMAN,tr|H3BSK9|H3BSK9_HUMAN,tr|H3BUE3|H3BUE3_HUMAN,tr|H3BUF6|H3BUF6_HUMAN" 5 1070.5033 1.31 46854 12623 2 1070.50285 536.2589 Ataxin-2-like protein OS=Homo sapiens OX=9606 GN=ATXN2L PE=1 SV=2 5.83 2456.9 - 3.76E+06 - - - -0.397 - 1.606 0.47 - 118.7 1 2 0 -0.0004 9 0 0 0 4.65E+07 3.55E+07 - - - 3.8829 0.7861 221125_WJC_METTL3_EV_vs_WT_F04.12624.12624.2 1.19 20-Sep P.EAVVTLNNQIK.V "sp|Q15155|NOMO1_HUMAN,sp|Q5JPE7|NOMO2_HUMAN,sp|P69849|NOMO3_HUMAN,tr|A0A7I2V3P4|A0A7I2V3P4_HUMAN,tr|A0A7I2V6B0|A0A7I2V6B0_HUMAN,tr|A0A7I2V4D7|A0A7I2V4D7_HUMAN,tr|A0A7I2V4T6|A0A7I2V4T6_HUMAN,tr|A0A0G2JP90|A0A0G2JP90_HUMAN,tr|A0A087X117|A0A087X117_HUMAN,tr|A0A0G2JN29|A0A0G2JN29_HUMAN,tr|A0A7I2V2Z5|A0A7I2V2Z5_HUMAN,tr|A0A087WW46|A0A087WW46_HUMAN,tr|J3KN36|J3KN36_HUMAN" 13 1227.6823 999 46855 12624 2 1227.682295 614.8484 Nodal modulator 1 OS=Homo sapiens OX=9606 GN=NOMO1 PE=1 SV=5 6.1 2457 - 1.00E+06 - - - -0.0057 - 1.339 0.182 - 264.1 1 1 0 0 11 0 0 0 1.14E+07 0.00E+00 - - - 1.175 0.9998 221125_WJC_METTL3_EV_vs_WT_F04.12627.12627.2 1.83E-05 20-Sep K.VSSQSFSEIER.Q "sp|Q8N6H7|ARFG2_HUMAN,tr|E9PIY6|E9PIY6_HUMAN,tr|E9PQP3|E9PQP3_HUMAN,tr|G5E9L0|G5E9L0_HUMAN,tr|A0A0D9SF70|A0A0D9SF70_HUMAN" 5 1267.6044 0.56 46858 12627 2 1267.605696 634.8095 ADP-ribosylation factor GTPase-activating protein 2 OS=Homo sapiens OX=9606 GN=ARFGAP2 PE=1 SV=1 4.53 2457.3 - 1.09E+06 - - - 0.9869 - 2.484 0.452 - 255.5 1 2 0 0.0013 11 0 0 0 7.43E+07 1.33E+08 - - - 4.8405 0.9997 221125_WJC_METTL3_EV_vs_WT_F04.12628.12628.2 0.00078 20-Sep K.QQVQVVGLQER.E "sp|O00139|KIF2A_HUMAN,tr|D6R9M0|D6R9M0_HUMAN,tr|A0A6Q8PFA6|A0A6Q8PFA6_HUMAN,tr|A0A6Q8PGH7|A0A6Q8PGH7_HUMAN,tr|H0Y8H2|H0Y8H2_HUMAN,tr|A0A6Q8PG37|A0A6Q8PG37_HUMAN,tr|A0A6Q8PH57|A0A6Q8PH57_HUMAN" 7 1282.6993 0.92 46859 12628 2 1282.700236 642.357 Kinesin-like protein KIF2A OS=Homo sapiens OX=9606 GN=KIF2A PE=1 SV=3 6 2457.4 - 952685 - - - 0.6915 - 1.959 0.405 - 341.6 1 2 0 0.0009 11 0 0 0 1.18E+07 1.28E+07 - - - 3.8511 0.9982 221125_WJC_METTL3_EV_vs_WT_F04.12629.12629.3 0.0214 Nov-52 R.FLITHNPTNATLNK[136.11].F "sp|Q93096|TP4A1_HUMAN,sp|Q12974|TP4A2_HUMAN,tr|E9PRR9|E9PRR9_HUMAN,tr|E9PMY3|E9PMY3_HUMAN,tr|E9PJC0|E9PJC0_HUMAN,tr|A0A3B3ISR8|A0A3B3ISR8_HUMAN,tr|E9PML8|E9PML8_HUMAN,tr|A0A0D9SGK2|A0A0D9SGK2_HUMAN" 8 1590.8609 1 46860 12629 3 1590.861269 531.2943 Protein tyrosine phosphatase type IVA 1 OS=Homo sapiens OX=9606 GN=PTP4A1 PE=1 SV=2 8.76 2457.5 - 931272 - - - 0.2062 - 1.761 0.257 - 66.7 1 2 0 0.0003 14 0 0 0 1.86E+07 1.86E+07 - - - 2.9091 0.9996 221125_WJC_METTL3_EV_vs_WT_F04.12631.12631.3 8.08E-05 15/44 K.NLDDGIDDER[166.11]LR[166.11].K "sp|Q9H361|PABP3_HUMAN,sp|P11940|PABP1_HUMAN,tr|A0A7I2YQE4|A0A7I2YQE4_HUMAN,tr|A0A7I2V649|A0A7I2V649_HUMAN,tr|H0YAR2|H0YAR2_HUMAN,tr|E7ERJ7|E7ERJ7_HUMAN,tr|A0A7I2YQ88|A0A7I2YQ88_HUMAN,tr|A0A087WTT1|A0A087WTT1_HUMAN,tr|H0YAP2|H0YAP2_HUMAN,tr|A0A7I2V4N4|A0A7I2V4N4_HUMAN,tr|E7EQV3|E7EQV3_HUMAN" 11 1449.6963 1.5 46862 12631 3 1449.69732 484.2394 Polyadenylate-binding protein 3 OS=Homo sapiens OX=9606 GN=PABPC3 PE=1 SV=2 4.04 2457.7 - 465243 - - - 0.7208 - 2.084 0.433 - 418.8 1 2 1 0.001 12 0 0 0 1.41E+08 9.42E+07 - - - 5.4026 0.9999 221125_WJC_METTL3_EV_vs_WT_F04.12632.12632.2 6.17E-06 22-Aug R.ADPTVESEEAFK.N "sp|Q15014|MO4L2_HUMAN,tr|Q5JXX2|Q5JXX2_HUMAN,tr|Q5JXX1|Q5JXX1_HUMAN" 3 1321.6038 1.56 46863 12632 2 1321.60278 661.8092 Mortality factor 4-like protein 2 OS=Homo sapiens OX=9606 GN=MORF4L2 PE=1 SV=1 4 2457.9 - 456192 - - - -0.7544 - 1.877 0.546 - 205.9 1 2 0 -0.001 12 0 0 0 5.06E+06 3.24E+06 - - - 4.7302 0.8147 221125_WJC_METTL3_EV_vs_WT_F04.12634.12634.2 54.1 24-Mar R.SC[160.03]DSDEDYEASGR[166.11].S sp|Q8IVE3|PKHH2_HUMAN 1 1499.5346 0.18 46865 12634 2 1499.535964 750.7746 Pleckstrin homology domain-containing family H member 2 OS=Homo sapiens OX=9606 GN=PLEKHH2 PE=1 SV=2 3.77 2458.1 - 266376 - - - 0.9089 - 0.595 0.149 - 27.3 1 2 0 0.0014 13 0 0 0 4.92E+05 2.72E+06 - - - -1.1914 0.9999 221125_WJC_METTL3_EV_vs_WT_F04.12635.12635.2 1.83E-06 22-Sep R.EYQAGDFEAAER[166.11].H "sp|O15294|OGT1_HUMAN,tr|C9JZL3|C9JZL3_HUMAN" 2 1394.5978 0.72 46866 12635 2 1394.598205 698.3062 UDP-N-acetylglucosamine--peptide N-acetylglucosaminyltransferase 110 kDa subunit OS=Homo sapiens OX=9606 GN=OGT PE=1 SV=3 4 2458.2 - 246790 - - - 0.2954 - 1.954 0.521 - 325.3 1 2 0 0.0004 12 0 0 0 2.07E+06 2.88E+06 - - - 4.6515 0.9781 221125_WJC_METTL3_EV_vs_WT_F04.12636.12636.2 0.17 18-Jun R.TNNPLPLEQR[166.11].L "sp|Q9UIA9|XPO7_HUMAN,tr|H0YBE1|H0YBE1_HUMAN,tr|E7ESC6|E7ESC6_HUMAN" 3 1190.6283 1.53 46867 12636 2 1190.629887 596.3214 Exportin-7 OS=Homo sapiens OX=9606 GN=XPO7 PE=1 SV=3 5.66 2458.4 - 300850 - - - 1.3279 - 1.26 0.095 - 116.9 1 2 0 0.0016 10 0 0 0 3.70E+06 2.42E+06 - - - 0.3873 1 221125_WJC_METTL3_EV_vs_WT_F04.12637.12637.2 6.26E-08 28-Dec R.VVSSTSEEEEAFTEK[136.11].F sp|Q8N573|OXR1_HUMAN 1 1678.7665 0.91 46868 12637 2 1678.764666 840.3905 Oxidation resistance protein 1 OS=Homo sapiens OX=9606 GN=OXR1 PE=1 SV=2 3.98 2458.5 - 153289 - - - -1.0871 - 2.408 0.639 - 300.3 1 2 0 -0.0018 15 0 0 0 5.68E+06 6.22E+06 - - - 5.9206 0.9989 221125_WJC_METTL3_EV_vs_WT_F04.12641.12641.3 0.0126 Oct-40 K.LSHETVTIELK.N "sp|P62314|SMD1_HUMAN,tr|J3QLR7|J3QLR7_HUMAN" 2 1268.6976 0.6 46870 12641 3 1268.7 423.9065 Small nuclear ribonucleoprotein Sm D1 OS=Homo sapiens OX=9606 GN=SNRPD1 PE=1 SV=1 5.4 2458.9 - 3.47E+06 - - - 1.8783 - 1.927 0.293 - 245.8 1 2 0 0.0024 11 0 0 0 3.87E+07 6.45E+07 - - - 3.6695 0.9998 221125_WJC_METTL3_EV_vs_WT_F04.12642.12642.3 3.04E-05 13/44 K.NLDDGIDDERLR.K "sp|Q9H361|PABP3_HUMAN,sp|P11940|PABP1_HUMAN,tr|A0A7I2YQE4|A0A7I2YQE4_HUMAN,tr|A0A7I2V649|A0A7I2V649_HUMAN,tr|H0YAR2|H0YAR2_HUMAN,tr|E7ERJ7|E7ERJ7_HUMAN,tr|A0A7I2YQ88|A0A7I2YQ88_HUMAN,tr|A0A087WTT1|A0A087WTT1_HUMAN,tr|H0YAP2|H0YAP2_HUMAN,tr|A0A7I2V4N4|A0A7I2V4N4_HUMAN,tr|E7EQV3|E7EQV3_HUMAN" 11 1429.6797 1.5 46871 12642 3 1429.679297 477.5672 Polyadenylate-binding protein 3 OS=Homo sapiens OX=9606 GN=PABPC3 PE=1 SV=2 4.04 2459 - 2.27E+06 - - - -0.3064 - 1.983 0.493 - 345.5 1 2 1 -0.0004 12 0 0 0 1.41E+08 9.42E+07 - - - 5.934 0.9999 221125_WJC_METTL3_EV_vs_WT_F04.12643.12643.2 5.52E-05 20-Aug K.EDGQEYAQVIK[136.11].M "sp|O14602|IF1AY_HUMAN,sp|P47813|IF1AX_HUMAN,tr|A6NJH9|A6NJH9_HUMAN" 3 1286.6234 1.04 46872 12643 2 1286.622257 644.319 "Eukaryotic translation initiation factor 1A, Y-chromosomal OS=Homo sapiens OX=9606 GN=EIF1AY PE=1 SV=4" 4.14 2459.1 - 1.59E+06 - - - -0.8853 - 1.996 0.525 - 304.6 1 2 0 -0.0011 11 0 0 0 1.73E+08 1.67E+08 - - - 4.788 0.9999 221125_WJC_METTL3_EV_vs_WT_F04.12644.12644.3 0.00655 20/52 R.FLITHNPTNATLNK.F "sp|Q93096|TP4A1_HUMAN,sp|Q12974|TP4A2_HUMAN,tr|E9PRR9|E9PRR9_HUMAN,tr|E9PMY3|E9PMY3_HUMAN,tr|E9PJC0|E9PJC0_HUMAN,tr|A0A3B3ISR8|A0A3B3ISR8_HUMAN,tr|E9PML8|E9PML8_HUMAN,tr|A0A0D9SGK2|A0A0D9SGK2_HUMAN" 8 1582.8467 1.01 46873 12644 3 1582.846057 528.6229 Protein tyrosine phosphatase type IVA 1 OS=Homo sapiens OX=9606 GN=PTP4A1 PE=1 SV=2 8.76 2459.1 - 1.54E+06 - - - -0.4321 - 2.524 0.418 - 330.6 1 2 0 -0.0007 14 0 0 0 1.86E+07 1.84E+07 - - - 5.6606 0.9996 221125_WJC_METTL3_EV_vs_WT_F04.12645.12645.2 0.0189 14-Sep R.K[136.11]IFTFAEK[136.11].Y "sp|P54577|SYYC_HUMAN,tr|A0A6Q8PFX4|A0A6Q8PFX4_HUMAN,tr|A0A0C4DGZ5|A0A0C4DGZ5_HUMAN,tr|A0A6Q8PFX2|A0A6Q8PFX2_HUMAN" 4 998.5772 1.01 46874 12645 2 998.576408 500.2959 "Tyrosine--tRNA ligase, cytoplasmic OS=Homo sapiens OX=9606 GN=YARS1 PE=1 SV=4" 8.59 2459.2 - 963423 - - - -0.7611 - 1.8 0.328 - 331.9 1 2 0 -0.0008 8 0 0 0 1.48E+07 1.46E+07 - - - 3.2361 0.9996 221125_WJC_METTL3_EV_vs_WT_F04.12646.12646.2 0.0296 16-Sep K.VELQELNDR[166.11].F "sp|P08670|VIME_HUMAN,sp|P17661|DESM_HUMAN,tr|B0YJC4|B0YJC4_HUMAN,tr|A0A1B0GTT5|A0A1B0GTT5_HUMAN" 4 1124.5701 2.03 46875 12646 2 1124.570272 563.2923 Vimentin OS=Homo sapiens OX=9606 GN=VIM PE=1 SV=4 4.14 2459.4 - 915646 - - - 0.1334 - 2.027 0.288 - 406.6 1 2 0 0.0001 9 0 0 0 1.59E+08 7.86E+07 - - - 3.2122 0.9999 221125_WJC_METTL3_EV_vs_WT_F04.12647.12647.2 3.87E-06 26-Dec K.TALPAQSAATLPAR.T "sp|Q01082|SPTB2_HUMAN,tr|A0A087WUZ3|A0A087WUZ3_HUMAN" 2 1366.7569 1.55 46876 12647 2 1366.756599 684.3857 "Spectrin beta chain, non-erythrocytic 1 OS=Homo sapiens OX=9606 GN=SPTBN1 PE=1 SV=2" 9.41 2459.5 - 903436 - - - -0.1939 - 2.576 0.577 - 546.6 1 2 0 -0.0003 14 0 0 0 1.49E+07 9.65E+06 - - - 5.6772 0.9998 221125_WJC_METTL3_EV_vs_WT_F04.12648.12648.3 0.000266 Dec-36 K.QHEGLATFYR[166.11].K "sp|Q6L8Q7|PDE12_HUMAN,tr|F6T1Q0|F6T1Q0_HUMAN" 2 1230.6021 0.65 46877 12648 3 1230.600234 411.208 "2',5'-phosphodiesterase 12 OS=Homo sapiens OX=9606 GN=PDE12 PE=1 SV=2" 6.75 2459.6 - 754397 - - - -1.509 - 2.012 0.363 - 218.4 1 2 0 -0.0019 10 0 0 0 8.40E+06 1.30E+07 - - - 4.6283 1 221125_WJC_METTL3_EV_vs_WT_F04.12649.12649.2 2.76E-07 22-Dec K.FQETSDEFEAAR.K "sp|Q14683|SMC1A_HUMAN,tr|G8JLG1|G8JLG1_HUMAN,tr|A0A6Q8PHC3|A0A6Q8PHC3_HUMAN,tr|V9GY57|V9GY57_HUMAN" 4 1428.6157 1.16 46878 12649 2 1428.613738 715.3151 Structural maintenance of chromosomes protein 1A OS=Homo sapiens OX=9606 GN=SMC1A PE=1 SV=2 4 2459.8 - 569906 - - - -1.4 - 2.19 0.646 - 425.6 1 2 0 -0.002 12 0 0 0 4.55E+06 3.92E+06 - - - 5.8743 1 221125_WJC_METTL3_EV_vs_WT_F04.12650.12650.2 4.76E-09 15/26 K.VDEAVAVLQAHQAK[136.11].E "sp|Q9H361|PABP3_HUMAN,sp|P11940|PABP1_HUMAN,tr|H0YAS6|H0YAS6_HUMAN,tr|H0YB75|H0YB75_HUMAN,tr|H0YAS7|H0YAS7_HUMAN,tr|A0A7I2YQE4|A0A7I2YQE4_HUMAN,tr|A0A7I2V649|A0A7I2V649_HUMAN,tr|H0YC10|H0YC10_HUMAN,tr|H0YAR2|H0YAR2_HUMAN,tr|E7ERJ7|E7ERJ7_HUMAN,tr|A0A7I2YQ88|A0A7I2YQ88_HUMAN,tr|A0A087WTT1|A0A087WTT1_HUMAN,tr|A0A7I2YQ90|A0A7I2YQ90_HUMAN,tr|A0A7I2V4N4|A0A7I2V4N4_HUMAN,tr|E7EQV3|E7EQV3_HUMAN" 15 1485.8031 1.34 46879 12650 2 1485.802223 743.9088 Polyadenylate-binding protein 3 OS=Homo sapiens OX=9606 GN=PABPC3 PE=1 SV=2 5.32 2459.9 - 518415 - - - -0.5849 - 2.807 0.595 - 359.7 1 2 0 -0.0009 14 0 0 0 7.07E+06 5.26E+06 - - - 6.0254 1 221125_WJC_METTL3_EV_vs_WT_F04.12651.12651.2 1.84E-10 14/28 R.VVSSTSEEEEAFTEK.F sp|Q8N573|OXR1_HUMAN 1 1670.7523 0.91 46880 12651 2 1670.751442 836.3834 Oxidation resistance protein 1 OS=Homo sapiens OX=9606 GN=OXR1 PE=1 SV=2 3.98 2460 - 429418 - - - -0.5082 - 2.92 0.652 - 516.3 1 2 0 -0.0008 15 0 0 0 5.68E+06 6.22E+06 - - - 6.4909 0.9998 221125_WJC_METTL3_EV_vs_WT_F04.12652.12652.3 0.00165 Nov-40 R.LHQLTETLIQK.Q "sp|Q8TBA6|GOGA5_HUMAN,tr|H0YK03|H0YK03_HUMAN" 2 1322.7558 2.31 46881 12652 3 1322.755054 441.9259 Golgin subfamily A member 5 OS=Homo sapiens OX=9606 GN=GOLGA5 PE=1 SV=3 6.75 2460.1 - 403537 - - - -0.5647 - 2.441 0.33 - 271.4 1 2 0 -0.0007 11 0 0 0 2.66E+07 1.15E+07 - - - 4.7541 0.9996 221125_WJC_METTL3_EV_vs_WT_F04.12653.12653.2 2.12E-05 18-Sep K.INFDSNSAYR[166.11].Q "sp|Q9P2R7|SUCB1_HUMAN,tr|Q5T9Q5|Q5T9Q5_HUMAN,tr|A0A2R8YDQ9|A0A2R8YDQ9_HUMAN,tr|A0A2R8Y6Y7|A0A2R8Y6Y7_HUMAN,tr|Q5T9Q8|Q5T9Q8_HUMAN" 5 1195.5497 1.74 46882 12653 2 1195.552822 598.7821 "Succinate--CoA ligase [ADP-forming] subunit beta, mitochondrial OS=Homo sapiens OX=9606 GN=SUCLA2 PE=1 SV=3" 5.84 2460.3 - 373713 - - - 2.5938 - 2.102 0.516 - 229.8 1 2 0 0.0031 10 0 0 0 8.82E+06 5.06E+06 - - - 4.9248 0.9831 221125_WJC_METTL3_EV_vs_WT_F04.12654.12654.2 0.149 20-Jul K.QQVQVVGLQER[166.11].E "sp|O00139|KIF2A_HUMAN,tr|D6R9M0|D6R9M0_HUMAN,tr|A0A6Q8PFA6|A0A6Q8PFA6_HUMAN,tr|A0A6Q8PGH7|A0A6Q8PGH7_HUMAN,tr|H0Y8H2|H0Y8H2_HUMAN,tr|A0A6Q8PG37|A0A6Q8PG37_HUMAN,tr|A0A6Q8PH57|A0A6Q8PH57_HUMAN" 7 1292.7076 0.92 46883 12654 2 1292.708581 647.3611 Kinesin-like protein KIF2A OS=Homo sapiens OX=9606 GN=KIF2A PE=1 SV=3 6 2460.4 - 321300 - - - 0.7442 - 1.487 0.054 - 122.4 2 2 0 0.001 11 0 0 0 1.18E+07 1.28E+07 - - - 0.3784 0.9999 221125_WJC_METTL3_EV_vs_WT_F04.12658.12658.3 0.00202 Dec-40 R.QFESLPATHIR.G sp|O94776|MTA2_HUMAN 1 1297.6779 1.12 46885 12658 3 1297.676633 433.5666 Metastasis-associated protein MTA2 OS=Homo sapiens OX=9606 GN=MTA2 PE=1 SV=1 6.75 2460.9 - 1.36E+06 - - - -0.9648 - 2.222 0.431 - 318.8 1 2 0 -0.0013 11 0 0 0 1.71E+07 1.53E+07 - - - 5.613 1 221125_WJC_METTL3_EV_vs_WT_F04.12659.12659.2 6.76E-09 22-Dec R.INVYYNEATGGK.Y sp|P68371|TBB4B_HUMAN 1 1327.6408 0.99 46886 12659 2 1327.640252 664.8277 Tubulin beta-4B chain OS=Homo sapiens OX=9606 GN=TUBB4B PE=1 SV=1 6 2461 - 1.05E+06 - - - -0.4361 - 2.572 0.599 - 499 1 2 0 -0.0006 12 0 0 0 1.01E+08 1.02E+08 - - - 5.9507 0.9998 221125_WJC_METTL3_EV_vs_WT_F04.12661.12661.3 0.00063 13/36 K.QHEGLATFYR.K "sp|Q6L8Q7|PDE12_HUMAN,tr|F6T1Q0|F6T1Q0_HUMAN" 2 1220.5938 0.66 46888 12661 3 1220.593747 407.8719 "2',5'-phosphodiesterase 12 OS=Homo sapiens OX=9606 GN=PDE12 PE=1 SV=2" 6.75 2461.2 - 845476 - - - -0.0606 - 1.853 0.393 - 208.5 1 2 0 -0.0001 10 0 0 0 8.44E+06 1.29E+07 - - - 4.7229 0.9999 221125_WJC_METTL3_EV_vs_WT_F04.12662.12662.2 8.09E-08 16/26 K.VDEAVAVLQAHQAK.E "sp|Q9H361|PABP3_HUMAN,sp|P11940|PABP1_HUMAN,tr|H0YAS6|H0YAS6_HUMAN,tr|H0YB75|H0YB75_HUMAN,tr|H0YAS7|H0YAS7_HUMAN,tr|A0A7I2YQE4|A0A7I2YQE4_HUMAN,tr|A0A7I2V649|A0A7I2V649_HUMAN,tr|H0YC10|H0YC10_HUMAN,tr|H0YAR2|H0YAR2_HUMAN,tr|E7ERJ7|E7ERJ7_HUMAN,tr|A0A7I2YQ88|A0A7I2YQ88_HUMAN,tr|A0A087WTT1|A0A087WTT1_HUMAN,tr|A0A7I2YQ90|A0A7I2YQ90_HUMAN,tr|A0A7I2V4N4|A0A7I2V4N4_HUMAN,tr|E7EQV3|E7EQV3_HUMAN" 15 1477.7889 1.34 46889 12662 2 1477.786824 739.9017 Polyadenylate-binding protein 3 OS=Homo sapiens OX=9606 GN=PABPC3 PE=1 SV=2 5.32 2461.3 - 779081 - - - -1.3994 - 2.817 0.541 - 1065.8 1 2 0 -0.0021 14 0 0 0 7.07E+06 5.26E+06 - - - 5.6351 0.9987 221125_WJC_METTL3_EV_vs_WT_F04.12664.12664.2 0.0654 16-Oct K.R[166.11]LLGQIVDR[166.11].C sp|Q96I24|FUBP3_HUMAN 1 1088.6569 1.98 46891 12664 2 1088.658129 545.3357 Far upstream element-binding protein 3 OS=Homo sapiens OX=9606 GN=FUBP3 PE=1 SV=2 9.6 2461.6 - 537913 - - - 1.1133 - 1.582 0.283 - 204.4 1 2 0 0.0012 9 0 0 0 2.33E+07 1.18E+07 - - - 2.4579 0.8536 221125_WJC_METTL3_EV_vs_WT_F04.12665.12665.3 4.71 Jul-36 K.ALYEQSLHIK.S "sp|P61201|CSN2_HUMAN,tr|H0YKU5|H0YKU5_HUMAN,tr|B4DIH5|B4DIH5_HUMAN,tr|H0YM03|H0YM03_HUMAN" 4 1200.6503 0.71 46892 12665 3 1200.650753 401.224 COP9 signalosome complex subunit 2 OS=Homo sapiens OX=9606 GN=COPS2 PE=1 SV=1 6.79 2461.7 - 434124 - - - 0.3998 - 1.255 0.103 - 48.2 2 2 0 0.0005 10 0 0 0 2.72E+06 3.85E+06 - - - 0.2122 0.9454 221125_WJC_METTL3_EV_vs_WT_F04.12667.12667.2 0.00106 13/22 M.MAGIDDC[160.03]YTSAR.G "sp|P15880|RS2_HUMAN,tr|I3L404|I3L404_HUMAN,tr|E9PM36|E9PM36_HUMAN,tr|E9PQD7|E9PQD7_HUMAN,tr|H0YEN5|H0YEN5_HUMAN" 5 1358.5595 1.07 46894 12667 2 1358.565077 680.287 40S ribosomal protein S2 OS=Homo sapiens OX=9606 GN=RPS2 PE=1 SV=2 4.21 2462 - 360200 - - - 4.1154 - 2.483 0.538 - 515.3 1 1 0 0.0056 12 0 0 0 3.66E+06 3.41E+06 - - - 5.4059 0.9137 221125_WJC_METTL3_EV_vs_WT_F04.12669.12669.2 7.17 26-Apr R.FLITHNPTNATLNK[136.11].F "sp|Q93096|TP4A1_HUMAN,sp|Q12974|TP4A2_HUMAN,tr|E9PRR9|E9PRR9_HUMAN,tr|E9PMY3|E9PMY3_HUMAN,tr|E9PJC0|E9PJC0_HUMAN,tr|A0A3B3ISR8|A0A3B3ISR8_HUMAN,tr|E9PML8|E9PML8_HUMAN,tr|A0A0D9SGK2|A0A0D9SGK2_HUMAN" 8 1590.8609 -1 46896 12669 2 1590.860831 796.4377 Protein tyrosine phosphatase type IVA 1 OS=Homo sapiens OX=9606 GN=PTP4A1 PE=1 SV=2 8.76 2462.2 - 0 - - - -0.0691 - 0.895 0.088 - 20.8 3 2 0 -0.0001 14 0 0 0 0.00E+00 0.00E+00 - - - -0.8006 1 221125_WJC_METTL3_EV_vs_WT_F04.12673.12673.3 2.13E-06 16/48 K.LTQVLNTHYVAPR[166.11].R "sp|P51531|SMCA2_HUMAN,sp|P51532|SMCA4_HUMAN,tr|A0A2R8Y7S2|A0A2R8Y7S2_HUMAN,tr|A0A2R8Y7F3|A0A2R8Y7F3_HUMAN,tr|A0A2R8YGG3|A0A2R8YGG3_HUMAN,tr|A0A0U1RQZ9|A0A0U1RQZ9_HUMAN,tr|A0A2R8Y523|A0A2R8Y523_HUMAN,tr|A0A2R8Y6V2|A0A2R8Y6V2_HUMAN,tr|Q9HBD4|Q9HBD4_HUMAN,tr|A0A2R8YCY3|A0A2R8YCY3_HUMAN,tr|A0A2R8Y440|A0A2R8Y440_HUMAN,tr|A0A2R8YDA1|A0A2R8YDA1_HUMAN,tr|A0A2R8Y7Y7|A0A2R8Y7Y7_HUMAN,tr|A0A2R8YF58|A0A2R8YF58_HUMAN,tr|A0A2R8Y526|A0A2R8Y526_HUMAN,tr|A0A2R8YG32|A0A2R8YG32_HUMAN,tr|A0A2R8YFV8|A0A2R8YFV8_HUMAN,tr|A0A2R8YGP5|A0A2R8YGP5_HUMAN,tr|A0A2R8Y6N0|A0A2R8Y6N0_HUMAN,tr|A0A2R8YF80|A0A2R8YF80_HUMAN,tr|A0A2R8Y4R6|A0A2R8Y4R6_HUMAN,tr|A0A2R8Y4P4|A0A2R8Y4P4_HUMAN,tr|A0A2R8Y4C5|A0A2R8Y4C5_HUMAN" 23 1520.8339 0.69 46898 12673 3 1520.833763 507.9519 Probable global transcription activator SNF2L2 OS=Homo sapiens OX=9606 GN=SMARCA2 PE=1 SV=2 8.75 2462.7 - 1.20E+06 - - - -0.0782 - 3.254 0.519 - 613.9 1 2 0 -0.0001 13 0 0 0 6.90E+06 1.00E+07 - - - 7.5253 0.9995 221125_WJC_METTL3_EV_vs_WT_F04.12674.12674.2 0.0448 18-Nov K.GNAAWQEQLK.Q "sp|P07814|SYEP_HUMAN,tr|V9GZ76|V9GZ76_HUMAN,tr|V9GYZ6|V9GYZ6_HUMAN" 3 1143.5673 1.18 46899 12674 2 1143.565522 572.7909 Bifunctional glutamate\proline--tRNA ligase OS=Homo sapiens OX=9606 GN=EPRS1 PE=1 SV=5 6 2462.8 - 1.19E+06 - - - -1.5303 - 1.994 0.348 - 435.4 1 2 0 -0.0018 10 0 0 0 2.08E+07 1.75E+07 - - - 3.5372 0.9835 221125_WJC_METTL3_EV_vs_WT_F04.12675.12675.2 0.0227 22-Aug K.NLDDGIDDERLR.K "sp|Q9H361|PABP3_HUMAN,sp|P11940|PABP1_HUMAN,tr|A0A7I2YQE4|A0A7I2YQE4_HUMAN,tr|A0A7I2V649|A0A7I2V649_HUMAN,tr|H0YAR2|H0YAR2_HUMAN,tr|E7ERJ7|E7ERJ7_HUMAN,tr|A0A7I2YQ88|A0A7I2YQ88_HUMAN,tr|A0A087WTT1|A0A087WTT1_HUMAN,tr|H0YAP2|H0YAP2_HUMAN,tr|A0A7I2V4N4|A0A7I2V4N4_HUMAN,tr|E7EQV3|E7EQV3_HUMAN" 11 1429.6797 1.69 46900 12675 2 1429.680042 715.8471 Polyadenylate-binding protein 3 OS=Homo sapiens OX=9606 GN=PABPC3 PE=1 SV=2 4.04 2462.9 - 1.03E+06 - - - 0.2147 - 1.199 0.342 - 105.5 1 2 1 0.0003 12 0 0 0 1.17E+07 6.92E+06 - - - 2.0444 0.9984 221125_WJC_METTL3_EV_vs_WT_F04.12676.12676.3 0.00771 Oct-40 R.LHQLTETLIQK[136.11].Q "sp|Q8TBA6|GOGA5_HUMAN,tr|H0YK03|H0YK03_HUMAN" 2 1330.77 2.31 46901 12676 3 1330.770301 444.5973 Golgin subfamily A member 5 OS=Homo sapiens OX=9606 GN=GOLGA5 PE=1 SV=3 6.75 2463 - 1.00E+06 - - - 0.2254 - 1.94 0.23 - 163.3 1 2 0 0.0003 11 0 0 0 2.66E+07 1.15E+07 - - - 2.9868 1 221125_WJC_METTL3_EV_vs_WT_F04.12677.12677.3 1.30E-05 18/48 K.LTQVLNTHYVAPR.R "sp|P51531|SMCA2_HUMAN,sp|P51532|SMCA4_HUMAN,tr|A0A2R8Y7S2|A0A2R8Y7S2_HUMAN,tr|A0A2R8Y7F3|A0A2R8Y7F3_HUMAN,tr|A0A2R8YGG3|A0A2R8YGG3_HUMAN,tr|A0A0U1RQZ9|A0A0U1RQZ9_HUMAN,tr|A0A2R8Y523|A0A2R8Y523_HUMAN,tr|A0A2R8Y6V2|A0A2R8Y6V2_HUMAN,tr|Q9HBD4|Q9HBD4_HUMAN,tr|A0A2R8YCY3|A0A2R8YCY3_HUMAN,tr|A0A2R8Y440|A0A2R8Y440_HUMAN,tr|A0A2R8YDA1|A0A2R8YDA1_HUMAN,tr|A0A2R8Y7Y7|A0A2R8Y7Y7_HUMAN,tr|A0A2R8YF58|A0A2R8YF58_HUMAN,tr|A0A2R8Y526|A0A2R8Y526_HUMAN,tr|A0A2R8YG32|A0A2R8YG32_HUMAN,tr|A0A2R8YFV8|A0A2R8YFV8_HUMAN,tr|A0A2R8YGP5|A0A2R8YGP5_HUMAN,tr|A0A2R8Y6N0|A0A2R8Y6N0_HUMAN,tr|A0A2R8YF80|A0A2R8YF80_HUMAN,tr|A0A2R8Y4R6|A0A2R8Y4R6_HUMAN,tr|A0A2R8Y4P4|A0A2R8Y4P4_HUMAN,tr|A0A2R8Y4C5|A0A2R8Y4C5_HUMAN" 23 1510.8256 0.69 46902 12677 3 1510.824276 504.6158 Probable global transcription activator SNF2L2 OS=Homo sapiens OX=9606 GN=SMARCA2 PE=1 SV=2 8.75 2463.1 - 839228 - - - -0.8843 - 3.234 0.49 - 795.6 1 2 0 -0.0013 13 0 0 0 6.90E+06 1.00E+07 - - - 7.1849 1 221125_WJC_METTL3_EV_vs_WT_F04.12678.12678.3 2.30E-05 13/40 K.SGYWASHLAGR[166.11].K sp|Q9NYU2|UGGG1_HUMAN 1 1213.5868 0.23 46903 12678 3 1213.586271 405.5362 UDP-glucose:glycoprotein glucosyltransferase 1 OS=Homo sapiens OX=9606 GN=UGGT1 PE=1 SV=3 8.49 2463.2 - 818826 - - - -0.4153 - 2.622 0.434 - 225.3 1 2 0 -0.0005 11 0 0 0 2.13E+06 9.22E+06 - - - 6.1169 0.9976 221125_WJC_METTL3_EV_vs_WT_F04.12679.12679.2 0.00195 18-Aug R.GSNTFTVVPK.R "sp|Q4KMQ1|TPRN_HUMAN,tr|H3BLU1|H3BLU1_HUMAN" 2 1048.5553 0.91 46904 12679 2 1048.55487 525.2849 Taperin OS=Homo sapiens OX=9606 GN=TPRN PE=1 SV=2 8.75 2463.3 - 597538 - - - -0.4196 - 1.791 0.133 - 192.9 1 2 0 -0.0004 10 0 0 0 7.83E+06 8.61E+06 - - - 1.6499 0.9998 221125_WJC_METTL3_EV_vs_WT_F04.12681.12681.2 9.89E-06 22-Oct R.MFTQQQPQELAR[166.11].D sp|Q96CX2|KCD12_HUMAN 1 1485.7274 3.51 46906 12681 2 1485.72599 743.871 BTB\POZ domain-containing protein KCTD12 OS=Homo sapiens OX=9606 GN=KCTD12 PE=1 SV=1 5.75 2463.6 - 450969 - - - -0.9275 - 2.133 0.483 - 126.1 1 2 0 -0.0014 12 0 0 0 1.48E+07 4.23E+06 - - - 4.6012 0.9999 221125_WJC_METTL3_EV_vs_WT_F04.12682.12682.2 0.000346 20-Dec R.LHQLTETLIQK.Q "sp|Q8TBA6|GOGA5_HUMAN,tr|H0YK03|H0YK03_HUMAN" 2 1322.7558 3.06 46907 12682 2 1322.755008 662.3852 Golgin subfamily A member 5 OS=Homo sapiens OX=9606 GN=GOLGA5 PE=1 SV=3 6.75 2463.7 - 346867 - - - -0.5995 - 2.339 0.446 - 461.3 1 2 0 -0.0008 11 0 0 0 5.08E+06 1.66E+06 - - - 4.6336 1 221125_WJC_METTL3_EV_vs_WT_F04.12685.12685.2 5.75E-06 14/30 A.AAAAAVTAASTSYYGR.D "sp|Q9BWF3|RBM4_HUMAN,tr|E9PB51|E9PB51_HUMAN" 2 1529.7474 1.63 46910 12685 2 1529.744509 765.881 RNA-binding protein 4 OS=Homo sapiens OX=9606 GN=RBM4 PE=1 SV=1 8.63 2464.1 - 269055 - - - -1.9036 - 3.092 0.537 - 581.5 1 1 0 -0.0029 16 0 0 0 2.03E+06 1.25E+06 - - - 5.7816 0.9994 221125_WJC_METTL3_EV_vs_WT_F04.12686.12686.3 2.78E-05 Oct-44 K.NLDDGIDDER[166.11]LR.K "sp|Q9H361|PABP3_HUMAN,sp|P11940|PABP1_HUMAN,tr|A0A7I2YQE4|A0A7I2YQE4_HUMAN,tr|A0A7I2V649|A0A7I2V649_HUMAN,tr|H0YAR2|H0YAR2_HUMAN,tr|E7ERJ7|E7ERJ7_HUMAN,tr|A0A7I2YQ88|A0A7I2YQ88_HUMAN,tr|A0A087WTT1|A0A087WTT1_HUMAN,tr|H0YAP2|H0YAP2_HUMAN,tr|A0A7I2V4N4|A0A7I2V4N4_HUMAN,tr|E7EQV3|E7EQV3_HUMAN" 11 1439.688 - 46911 12686 3 1439.689234 480.9033 Polyadenylate-binding protein 3 OS=Homo sapiens OX=9606 GN=PABPC3 PE=1 SV=2 4.04 2464.2 - 213458 - - - 0.8537 - 1.712 0.441 - 103.2 1 2 1 0.0012 12 0 0 0 - - - - - 4.9467 0.9996 221125_WJC_METTL3_EV_vs_WT_F04.12687.12687.2 1.05E-05 20-Dec K.QEYLNEYEAEK.L "sp|Q969G3|SMCE1_HUMAN,tr|A0A2R8Y855|A0A2R8Y855_HUMAN,tr|A0A2R8YEB8|A0A2R8YEB8_HUMAN,tr|A0A2R8YES3|A0A2R8YES3_HUMAN,tr|A0A2U3TZQ7|A0A2U3TZQ7_HUMAN,tr|A0A2R8Y7U4|A0A2R8Y7U4_HUMAN,tr|B4DGM3|B4DGM3_HUMAN,tr|A0A2R8YD78|A0A2R8YD78_HUMAN,tr|J3QKS7|J3QKS7_HUMAN,tr|A0A2R8Y4T4|A0A2R8Y4T4_HUMAN,tr|A0A2R8Y7I9|A0A2R8Y7I9_HUMAN,tr|J3QR61|J3QR61_HUMAN,tr|A0A2R8Y765|A0A2R8Y765_HUMAN,tr|J3KT85|J3KT85_HUMAN,tr|J3QKX6|J3QKX6_HUMAN,tr|A0A2R8YFC8|A0A2R8YFC8_HUMAN" 16 1414.6252 0.43 46912 12687 2 1414.629416 708.3199 SWI\SNF-related matrix-associated actin-dependent regulator of chromatin subfamily E member 1 OS=Homo sapiens OX=9606 GN=SMARCE1 PE=1 SV=2 4.09 2464.4 - 206279 - - - 2.952 - 2.232 0.544 - 500.3 1 2 0 0.0042 11 0 0 0 1.67E+06 3.91E+06 - - - 5.2297 0.9999 221125_WJC_METTL3_EV_vs_WT_F04.12689.12689.2 0.00882 22-Dec R.INVYYNEATGGK[136.11].Y sp|P68371|TBB4B_HUMAN 1 1335.655 0.99 46913 12689 2 1335.654458 668.8348 Tubulin beta-4B chain OS=Homo sapiens OX=9606 GN=TUBB4B PE=1 SV=1 6 2464.6 - 8.62E+06 - - - -0.429 - 2.461 0.52 - 437.1 1 2 0 -0.0006 12 0 0 0 1.01E+08 1.02E+08 - - - 5.2511 0.9987 221125_WJC_METTL3_EV_vs_WT_F04.12690.12690.3 0.00204 Nov-44 K.LKQSLPPGLAVK.E sp|P63173|RL38_HUMAN 1 1249.7758 1.15 46914 12690 3 1249.774801 417.5992 60S ribosomal protein L38 OS=Homo sapiens OX=9606 GN=RPL38 PE=1 SV=2 10 2464.6 - 3.43E+06 - - - -0.8057 - 2.208 0.315 - 217.8 1 2 1 -0.001 12 0 0 0 4.20E+07 3.66E+07 - - - 4.2472 1 221125_WJC_METTL3_EV_vs_WT_F04.12693.12693.2 1.94E-07 13/24 K.VQISPDSGGLPER[166.11].S "sp|Q92945|FUBP2_HUMAN,tr|M0QYH3|M0QYH3_HUMAN,tr|M0R0C6|M0R0C6_HUMAN,tr|M0QXW7|M0QXW7_HUMAN,tr|A0A087WTP3|A0A087WTP3_HUMAN" 5 1363.6971 1.25 46917 12693 2 1363.694889 682.8558 Far upstream element-binding protein 2 OS=Homo sapiens OX=9606 GN=KHSRP PE=1 SV=4 4.37 2464.8 - 1.71E+06 - - - -1.6316 - 2.855 0.576 - 411.6 1 2 0 -0.0022 13 0 0 0 1.27E+08 1.02E+08 - - - 5.9871 0.9993 221125_WJC_METTL3_EV_vs_WT_F04.12694.12694.2 0.0011 24-Nov K.VQISPDSGGLPER.S "sp|Q92945|FUBP2_HUMAN,tr|M0QYH3|M0QYH3_HUMAN,tr|M0R0C6|M0R0C6_HUMAN,tr|M0QXW7|M0QXW7_HUMAN,tr|A0A087WTP3|A0A087WTP3_HUMAN" 5 1353.6888 1.25 46918 12694 2 1353.691936 677.8517 Far upstream element-binding protein 2 OS=Homo sapiens OX=9606 GN=KHSRP PE=1 SV=4 4.37 2464.9 - 1.63E+06 - - - 2.2841 - 2.263 0.353 - 321.5 1 2 0 0.0031 13 0 0 0 1.27E+08 1.02E+08 - - - 3.7433 0.9957 221125_WJC_METTL3_EV_vs_WT_F04.12695.12695.2 0.0889 16-Aug K.RLLGQIVDR.C sp|Q96I24|FUBP3_HUMAN 1 1068.6404 1.98 46919 12695 2 1068.639837 535.3275 Far upstream element-binding protein 3 OS=Homo sapiens OX=9606 GN=FUBP3 PE=1 SV=2 9.6 2465 - 1.56E+06 - - - -0.5053 - 1.509 0.136 - 105.3 1 2 0 -0.0005 9 0 0 0 2.33E+07 1.18E+07 - - - 1.2357 0.9998 221125_WJC_METTL3_EV_vs_WT_F04.12697.12697.2 5.76E-06 16-Oct K.DGLTDVYNK.L "sp|P24752|THIL_HUMAN,tr|A0A5F9ZHJ7|A0A5F9ZHJ7_HUMAN,tr|A0A5F9ZHD4|A0A5F9ZHD4_HUMAN,tr|A0A5F9ZHH9|A0A5F9ZHH9_HUMAN,tr|A0A5F9ZHJ0|A0A5F9ZHJ0_HUMAN,tr|A0A5F9ZHL1|A0A5F9ZHL1_HUMAN,tr|A0A5F9ZI66|A0A5F9ZI66_HUMAN,tr|H0YEL7|H0YEL7_HUMAN" 8 1023.4873 1.25 46921 12697 2 1023.486429 512.7509 "Acetyl-CoA acetyltransferase, mitochondrial OS=Homo sapiens OX=9606 GN=ACAT1 PE=1 SV=1" 4.21 2465.2 - 968254 - - - -0.8412 - 1.946 0.497 - 270.9 1 2 0 -0.0009 9 0 0 0 4.64E+07 3.71E+07 - - - 4.6377 0.9995 221125_WJC_METTL3_EV_vs_WT_F04.12698.12698.3 0.00516 Nov-40 R.QLDGELGHLC[160.03]R.G "sp|Q969Y2|GTPB3_HUMAN,tr|M0R0S9|M0R0S9_HUMAN" 2 1296.6245 2.22 46922 12698 3 1296.622925 433.2154 "tRNA modification GTPase GTPBP3, mitochondrial OS=Homo sapiens OX=9606 GN=GTPBP3 PE=1 SV=2" 5.32 2465.3 - 905916 - - - -1.1908 - 1.901 0.316 - 220.2 1 2 0 -0.0015 11 0 0 0 1.02E+07 4.58E+06 - - - 3.8876 1 221125_WJC_METTL3_EV_vs_WT_F04.12699.12699.2 5.14E-05 15/22 K.VPAINVNDSVTK.S sp|P23526|SAHH_HUMAN 1 1255.6772 1.04 46923 12699 2 1255.676937 628.8459 Adenosylhomocysteinase OS=Homo sapiens OX=9606 GN=AHCY PE=1 SV=4 5.81 2465.4 - 776984 - - - -0.2222 - 2.762 0.551 - 724.6 1 2 0 -0.0003 12 0 0 0 4.15E+07 4.00E+07 - - - 5.7837 0.988 221125_WJC_METTL3_EV_vs_WT_F04.12700.12700.2 9.58E-06 22-Oct M.MAGIDDC[160.03]YTSAR[166.11].G "sp|P15880|RS2_HUMAN,tr|I3L404|I3L404_HUMAN,tr|E9PM36|E9PM36_HUMAN,tr|E9PQD7|E9PQD7_HUMAN,tr|H0YEN5|H0YEN5_HUMAN" 5 1368.5678 1.07 46924 12700 2 1368.568622 685.2912 40S ribosomal protein S2 OS=Homo sapiens OX=9606 GN=RPS2 PE=1 SV=2 4.21 2465.6 - 1.05E+06 - - - 0.6328 - 1.787 0.498 - 287.1 1 1 0 0.0009 12 0 0 0 3.66E+06 3.41E+06 - - - 4.2465 0.9999 221125_WJC_METTL3_EV_vs_WT_F04.12701.12701.2 1.27E-07 24-Nov K.VGAEELTADQNLK[136.11].F sp|P56182|RRP1_HUMAN 1 1394.7133 0.96 46925 12701 2 1394.712883 698.3639 Ribosomal RNA processing protein 1 homolog A OS=Homo sapiens OX=9606 GN=RRP1 PE=1 SV=1 4.14 2465.7 - 346434 - - - -0.2803 - 2.875 0.522 - 504.9 1 2 0 -0.0004 13 0 0 0 3.50E+06 3.63E+06 - - - 5.6068 0.9997 221125_WJC_METTL3_EV_vs_WT_F04.12705.12705.2 5.07E-05 20-Nov K.ISNYGWDQSDK[136.11].F sp|Q9HB71|CYBP_HUMAN 1 1319.5873 0.26 46928 12705 2 1319.583823 660.8009 Calcyclin-binding protein OS=Homo sapiens OX=9606 GN=CACYBP PE=1 SV=2 4.21 2466.3 - 500192 - - - -2.669 - 2.235 0.584 - 592.1 1 2 0 -0.0035 11 0 0 0 9.92E+05 3.80E+06 - - - 5.529 0.9999 221125_WJC_METTL3_EV_vs_WT_F04.12706.12706.2 6.38E-08 15/24 K.VGAEELTADQNLK.F sp|P56182|RRP1_HUMAN 1 1386.6991 0.96 46929 12706 2 1386.697555 694.3568 Ribosomal RNA processing protein 1 homolog A OS=Homo sapiens OX=9606 GN=RRP1 PE=1 SV=1 4.14 2466.4 - 501890 - - - -1.0954 - 2.967 0.52 - 892.1 1 2 0 -0.0015 13 0 0 0 3.50E+06 3.63E+06 - - - 5.6725 0.9987 221125_WJC_METTL3_EV_vs_WT_F04.12707.12707.2 0.0125 16-Aug K.DLSQNFPTK[136.11].A sp|Q9NYU2|UGGG1_HUMAN 1 1056.5331 0.17 46930 12707 2 1056.532271 529.2738 UDP-glucose:glycoprotein glucosyltransferase 1 OS=Homo sapiens OX=9606 GN=UGGT1 PE=1 SV=3 5.84 2466.4 - 2.67E+06 - - - -0.8083 - 1.493 0.274 - 188.9 1 2 0 -0.0009 9 0 0 0 6.09E+06 3.63E+07 - - - 2.224 0.9998 221125_WJC_METTL3_EV_vs_WT_F04.12708.12708.2 0.000339 16-Aug K.DGLTDVYNK[136.11].L "sp|P24752|THIL_HUMAN,tr|A0A5F9ZHJ7|A0A5F9ZHJ7_HUMAN,tr|A0A5F9ZHD4|A0A5F9ZHD4_HUMAN,tr|A0A5F9ZHH9|A0A5F9ZHH9_HUMAN,tr|A0A5F9ZHJ0|A0A5F9ZHJ0_HUMAN,tr|A0A5F9ZHL1|A0A5F9ZHL1_HUMAN,tr|A0A5F9ZI66|A0A5F9ZI66_HUMAN,tr|H0YEL7|H0YEL7_HUMAN" 8 1031.5015 1.25 46931 12708 2 1031.500428 516.758 "Acetyl-CoA acetyltransferase, mitochondrial OS=Homo sapiens OX=9606 GN=ACAT1 PE=1 SV=1" 4.21 2466.5 - 1.98E+06 - - - -1.0296 - 1.876 0.464 - 141.5 1 2 0 -0.0011 9 0 0 0 4.64E+07 3.71E+07 - - - 4.2879 0.9998 221125_WJC_METTL3_EV_vs_WT_F04.12710.12710.3 7.96E-05 Oct-32 K.SDPYLEFHK[136.11].Q "sp|O75131|CPNE3_HUMAN,tr|A0A087WYQ3|A0A087WYQ3_HUMAN" 2 1142.5488 0.07 46933 12710 3 1142.546791 381.8569 Copine-3 OS=Homo sapiens OX=9606 GN=CPNE3 PE=1 SV=1 5.3 2466.7 - 646888 - - - -1.7365 - 1.885 0.415 - 163.1 1 2 0 -0.002 9 0 0 0 7.04E+05 1.03E+07 - - - 5.0768 1 221125_WJC_METTL3_EV_vs_WT_F04.12715.12715.3 3.23E-05 21/60 R.LAAAQAAGLAAAHSVR.L "sp|Q6QNY0|BL1S3_HUMAN,tr|K7EN58|K7EN58_HUMAN" 2 1476.8161 2.59 46936 12715 3 1476.816515 493.2793 Biogenesis of lysosome-related organelles complex 1 subunit 3 OS=Homo sapiens OX=9606 GN=BLOC1S3 PE=1 SV=1 9.76 2467.4 - 2.50E+06 - - - 0.2742 - 3.981 0.408 - 648.6 1 2 0 0.0004 16 0 0 0 3.79E+07 1.46E+07 - - - 6.6335 0.9999 221125_WJC_METTL3_EV_vs_WT_F04.12716.12716.2 4.55E-05 22-Nov K.VGDPQELNGITR[166.11].A "sp|P49327|FAS_HUMAN,tr|A0A0U1RQF0|A0A0U1RQF0_HUMAN" 2 1307.6709 0.88 46937 12716 2 1307.670965 654.8427 Fatty acid synthase OS=Homo sapiens OX=9606 GN=FASN PE=1 SV=3 4.37 2467.4 - 1.30E+06 - - - 0.0505 - 2.378 0.514 - 441.5 1 2 0 0.0001 12 0 0 0 1.47E+07 1.67E+07 - - - 5.1167 1 221125_WJC_METTL3_EV_vs_WT_F04.12717.12717.2 1.38E-07 13/22 K.VPAINVNDSVTK[136.11].S sp|P23526|SAHH_HUMAN 1 1263.6914 1.05 46938 12717 2 1263.690055 632.853 Adenosylhomocysteinase OS=Homo sapiens OX=9606 GN=AHCY PE=1 SV=4 5.81 2467.5 - 2.87E+06 - - - -1.077 - 2.792 0.54 - 600.1 1 2 0 -0.0014 12 0 0 0 4.24E+07 4.03E+07 - - - 5.7306 0.9999 221125_WJC_METTL3_EV_vs_WT_F04.12721.12721.3 0.000298 Nov-40 R.NGHVGISFVPK[136.11].E "sp|P21333|FLNA_HUMAN,tr|Q60FE5|Q60FE5_HUMAN" 2 1161.6386 1.06 46942 12721 3 1161.636808 388.2201 Filamin-A OS=Homo sapiens OX=9606 GN=FLNA PE=1 SV=4 8.76 2467.9 - 879741 - - - -1.5366 - 2.013 0.412 - 141 1 2 0 -0.0018 11 0 0 0 1.03E+07 9.70E+06 - - - 5.1204 0.9974 221125_WJC_METTL3_EV_vs_WT_F04.12722.12722.3 0.00759 Nov-40 R.NGHVGISFVPK.E "sp|P21333|FLNA_HUMAN,tr|Q60FE5|Q60FE5_HUMAN" 2 1153.6244 1.01 46943 12722 3 1153.62203 385.5487 Filamin-A OS=Homo sapiens OX=9606 GN=FLNA PE=1 SV=4 8.76 2468 - 743350 - - - -2.0483 - 1.309 0.339 - 139.1 1 2 0 -0.0024 11 0 0 0 9.85E+06 9.80E+06 - - - 3.0838 0.9999 221125_WJC_METTL3_EV_vs_WT_F04.12723.12723.2 2.30E-05 15/24 R.LQQQLTQAQETLK.S "sp|Q9Y4P3|TBL2_HUMAN,tr|E9PF19|E9PF19_HUMAN" 2 1527.8257 1.15 46944 12723 2 1527.826025 764.9201 Transducin beta-like protein 2 OS=Homo sapiens OX=9606 GN=TBL2 PE=1 SV=1 6 2468.1 - 569144 - - - 0.2317 - 3.138 0.498 - 956.9 1 2 0 0.0004 13 0 0 0 1.05E+07 9.11E+06 - - - 5.6542 0.9992 221125_WJC_METTL3_EV_vs_WT_F04.12726.12726.2 0.00118 13/30 R.LPVAC[160.03]PNQC[160.03]GVGTVAR.E "sp|Q9BUZ4|TRAF4_HUMAN,tr|F6SA91|F6SA91_HUMAN" 2 1697.8341 6.4 46947 12726 2 1697.839571 849.9243 TNF receptor-associated factor 4 OS=Homo sapiens OX=9606 GN=TRAF4 PE=1 SV=1 8.07 2468.5 - 141832 - - - 3.1958 - 2.688 0.416 - 393.9 1 2 0 0.0054 16 0 0 0 9.05E+06 1.41E+06 - - - 4.5429 1 221125_WJC_METTL3_EV_vs_WT_F04.12730.12730.3 4.77E-06 17/48 R.EAAAALVEEETRR.Y sp|O75934|SPF27_HUMAN 1 1443.7318 1.42 46949 12730 3 1443.731877 482.2512 Pre-mRNA-splicing factor SPF27 OS=Homo sapiens OX=9606 GN=BCAS2 PE=1 SV=1 4.49 2468.9 - 4.28E+06 - - - 0.0734 - 2.792 0.448 - 557.3 1 2 0 0.0001 13 0 0 0 8.45E+07 5.94E+07 - - - 6.3186 0.9997 221125_WJC_METTL3_EV_vs_WT_F04.12731.12731.3 0.00286 Dec-44 M.VMEK[136.11]PSPLLVGR[166.11].E "sp|Q13283|G3BP1_HUMAN,sp|Q9UN86|G3BP2_HUMAN,tr|A0A7I2V3E2|A0A7I2V3E2_HUMAN,tr|A0A7I2V5M7|A0A7I2V5M7_HUMAN,tr|A0A7I2V2R0|A0A7I2V2R0_HUMAN,tr|E5RH00|E5RH00_HUMAN,tr|E5RH42|E5RH42_HUMAN,tr|A0A7I2V4Y8|A0A7I2V4Y8_HUMAN,tr|D6RAC7|D6RAC7_HUMAN,tr|D6RGJ4|D6RGJ4_HUMAN,tr|A0A7I2V3C4|A0A7I2V3C4_HUMAN,tr|A0A7P0P2U7|A0A7P0P2U7_HUMAN,tr|A0A7I2V2S5|A0A7I2V2S5_HUMAN,tr|D6RB17|D6RB17_HUMAN,tr|A0A7I2YQU8|A0A7I2YQU8_HUMAN,tr|E5RJU8|E5RJU8_HUMAN,tr|A0A7I2YQS2|A0A7I2YQS2_HUMAN,tr|A0A7I2YQD9|A0A7I2YQD9_HUMAN,tr|D6R9A4|D6R9A4_HUMAN,tr|A0A7I2V651|A0A7I2V651_HUMAN,tr|E5RIF8|E5RIF8_HUMAN,tr|E5RI46|E5RI46_HUMAN,tr|A0A7I2YQN9|A0A7I2YQN9_HUMAN,tr|D6RBR0|D6RBR0_HUMAN,tr|D6RBW8|D6RBW8_HUMAN" 25 1342.7762 1.5 46950 12731 3 1342.77544 448.5993 Ras GTPase-activating protein-binding protein 1 OS=Homo sapiens OX=9606 GN=G3BP1 PE=1 SV=1 8.72 2469 - 884364 - - - -0.5377 - 1.968 0.342 - 203.5 1 2 0 -0.0007 12 0 0 0 1.56E+07 1.05E+07 - - - 4.2294 1 221125_WJC_METTL3_EV_vs_WT_F04.12732.12732.2 1.25E-06 13/20 K.SGEEGMPDLAH.V "sp|O75688|PPM1B_HUMAN,tr|B8ZZF0|B8ZZF0_HUMAN,tr|A0A3B3IS24|A0A3B3IS24_HUMAN,tr|C9JIR6|C9JIR6_HUMAN" 4 1141.471 - 46951 12732 2 1141.47113 571.7428 Protein phosphatase 1B OS=Homo sapiens OX=9606 GN=PPM1B PE=1 SV=1 4.13 2469.1 - 1.26E+06 - - - 0.1244 - 2.406 0.62 - 761.7 1 1 0 0.0001 11 0 0 0 - - - - - 5.9954 1 221125_WJC_METTL3_EV_vs_WT_F04.12733.12733.2 2.74E-06 22-Dec R.NVEDLSGGELQR.F "sp|P61221|ABCE1_HUMAN,tr|D6R9I9|D6R9I9_HUMAN" 2 1315.6368 0.82 46952 12733 2 1315.634774 658.8257 ATP-binding cassette sub-family E member 1 OS=Homo sapiens OX=9606 GN=ABCE1 PE=1 SV=1 4.14 2469.3 - 631824 - - - -1.546 - 2.561 0.586 - 474.8 1 2 0 -0.002 12 0 0 0 1.50E+07 1.83E+07 - - - 5.8429 0.9998 221125_WJC_METTL3_EV_vs_WT_F04.12734.12734.2 0.00163 13/24 R.EAAAALVEEETRR.Y sp|O75934|SPF27_HUMAN 1 1443.7318 1.69 46953 12734 2 1443.731225 722.8732 Pre-mRNA-splicing factor SPF27 OS=Homo sapiens OX=9606 GN=BCAS2 PE=1 SV=1 4.49 2469.4 - 431572 - - - -0.3782 - 2.406 0.41 - 220.8 1 2 0 -0.0005 13 0 0 0 9.23E+06 5.47E+06 - - - 4.3224 0.9999 221125_WJC_METTL3_EV_vs_WT_F04.12738.12738.2 2.77E-07 26-Nov R.VLNGNQQVVDTSLK.Q sp|Q7Z417|NUFP2_HUMAN 1 1513.81 1.34 46957 12738 2 1513.810108 757.9123 Nuclear fragile X mental retardation-interacting protein 2 OS=Homo sapiens OX=9606 GN=NUFIP2 PE=1 SV=1 5.81 2469.9 - 277720 - - - 0.0575 - 2.667 0.458 - 341.2 1 2 0 0.0001 14 0 0 0 9.10E+06 6.81E+06 - - - 4.8854 1 221125_WJC_METTL3_EV_vs_WT_F04.12739.12739.2 1.76E-07 15/26 R.VLNGNQQVVDTSLK[136.11].Q sp|Q7Z417|NUFP2_HUMAN 1 1521.8242 1.34 46958 12739 2 1521.825046 761.9194 Nuclear fragile X mental retardation-interacting protein 2 OS=Homo sapiens OX=9606 GN=NUFIP2 PE=1 SV=1 5.81 2470 - 272651 - - - 0.5421 - 3.053 0.591 - 751.8 1 2 0 0.0008 14 0 0 0 9.10E+06 6.81E+06 - - - 6.2067 1 221125_WJC_METTL3_EV_vs_WT_F04.12741.12741.3 2.23E-05 17/48 R.EAAAALVEEETR[166.11]R[166.11].Y sp|O75934|SPF27_HUMAN 1 1463.7483 1.43 46959 12741 3 1463.747643 488.9234 Pre-mRNA-splicing factor SPF27 OS=Homo sapiens OX=9606 GN=BCAS2 PE=1 SV=1 4.49 2470.3 - 5.55E+06 - - - -0.4564 - 2.55 0.472 - 524.4 1 2 0 -0.0007 13 0 0 0 8.41E+07 5.90E+07 - - - 6.3402 1 221125_WJC_METTL3_EV_vs_WT_F04.12745.12745.3 3.21E-07 20/64 R.AQVQEFC[160.03]DYGTK[136.11]EEC[160.03]MK[136.11].A "sp|Q86U44|MTA70_HUMAN,tr|H0YFV6|H0YFV6_HUMAN" 2 2137.909 0.001 46962 12745 3 2138.905842 713.6436 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 4.41 2470.7 - 1.46E+06 - - - 466.2869 - 3.213 0.67 - 375.7 1 2 1 0.9969 17 0 0 0 0.00E+00 1.47E+07 - - - 8.6824 0.9999 221125_WJC_METTL3_EV_vs_WT_F04.12746.12746.2 1.13E-05 24-Nov R.LQQQLTQAQETLK[136.11].S "sp|Q9Y4P3|TBL2_HUMAN,tr|E9PF19|E9PF19_HUMAN" 2 1535.8399 1.15 46963 12746 2 1535.838241 768.9272 Transducin beta-like protein 2 OS=Homo sapiens OX=9606 GN=TBL2 PE=1 SV=1 6 2470.8 - 852701 - - - -1.0613 - 2.545 0.488 - 439.8 1 2 0 -0.0016 13 0 0 0 1.05E+07 9.11E+06 - - - 5.0423 0.9999 221125_WJC_METTL3_EV_vs_WT_F04.12747.12747.2 1.90E-06 13/22 R.VLQQFADNDVSR.F "sp|P51659|DHB4_HUMAN,tr|A0A2R8Y7L2|A0A2R8Y7L2_HUMAN,tr|A0A2R8YD50|A0A2R8YD50_HUMAN,tr|A0A804HIR1|A0A804HIR1_HUMAN,tr|E7ET17|E7ET17_HUMAN,tr|E7EPL9|E7EPL9_HUMAN,tr|A0A804HKU2|A0A804HKU2_HUMAN,tr|A0A804HK65|A0A804HK65_HUMAN" 8 1390.6841 0.56 46964 12747 2 1390.682624 696.3493 Peroxisomal multifunctional enzyme type 2 OS=Homo sapiens OX=9606 GN=HSD17B4 PE=1 SV=3 4.21 2471 - 578238 - - - -1.0563 - 2.594 0.513 - 825.9 1 2 0 -0.0015 12 0 0 0 1.10E+07 1.96E+07 - - - 5.3376 0.9529 221125_WJC_METTL3_EV_vs_WT_F04.12752.12752.3 0.285 Nov-44 K.LK[136.11]QSLPPGLAVK[136.11].E sp|P63173|RL38_HUMAN 1 1265.8042 1.07 46967 12752 3 1265.803447 422.942 60S ribosomal protein L38 OS=Homo sapiens OX=9606 GN=RPL38 PE=1 SV=2 10 2471.6 - 2.56E+06 - - - -0.6012 - 1.87 0.134 - 187.6 1 2 1 -0.0008 12 0 0 0 4.20E+07 3.93E+07 - - - 1.7688 0.9999 221125_WJC_METTL3_EV_vs_WT_F04.12753.12753.2 3.34E-08 13/22 R.VLQQFADNDVSR[166.11].F "sp|P51659|DHB4_HUMAN,tr|A0A2R8Y7L2|A0A2R8Y7L2_HUMAN,tr|A0A2R8YD50|A0A2R8YD50_HUMAN,tr|A0A804HIR1|A0A804HIR1_HUMAN,tr|E7ET17|E7ET17_HUMAN,tr|E7EPL9|E7EPL9_HUMAN,tr|A0A804HKU2|A0A804HKU2_HUMAN,tr|A0A804HK65|A0A804HK65_HUMAN" 8 1400.6924 0.56 46968 12753 2 1400.693334 701.3535 Peroxisomal multifunctional enzyme type 2 OS=Homo sapiens OX=9606 GN=HSD17B4 PE=1 SV=3 4.21 2471.6 - 1.58E+06 - - - 0.6932 - 2.588 0.437 - 846.5 1 2 0 0.001 12 0 0 0 1.10E+07 1.96E+07 - - - 4.7703 0.9992 221125_WJC_METTL3_EV_vs_WT_F04.12754.12754.2 0.00314 18-Sep K.VQSLQTALEK[136.11].T "sp|Q13948|CASP_HUMAN,sp|P39880|CUX1_HUMAN,tr|A0A2R8Y8D0|A0A2R8Y8D0_HUMAN,tr|A0A2R8Y852|A0A2R8Y852_HUMAN,tr|A0A2R8YDI1|A0A2R8YDI1_HUMAN" 5 1123.6328 1.36 46969 12754 2 1123.634461 562.8237 Protein CASP OS=Homo sapiens OX=9606 GN=CUX1 PE=1 SV=2 5.97 2471.7 - 903954 - - - 1.4435 - 1.945 0.285 - 322.8 1 2 0 0.0016 10 0 0 0 1.24E+07 9.14E+06 - - - 3.0024 0.993 221125_WJC_METTL3_EV_vs_WT_F04.12759.12759.3 0.161 Sep-60 R.AEVEALHSSGMTAVVK[136.11].F sp|Q9H7E2|TDRD3_HUMAN 1 1635.8382 0.91 46974 12759 3 1635.838084 546.2867 Tudor domain-containing protein 3 OS=Homo sapiens OX=9606 GN=TDRD3 PE=1 SV=1 5.4 2472.4 - 360909 - - - -0.0446 - 1.765 0.182 - 52.5 1 2 0 -0.0001 16 0 0 0 4.22E+06 4.66E+06 - - - 2.0269 0.9991 221125_WJC_METTL3_EV_vs_WT_F04.12764.12764.2 0.029 16-Aug K.VELQELNDR.F "sp|P08670|VIME_HUMAN,sp|P17661|DESM_HUMAN,tr|B0YJC4|B0YJC4_HUMAN,tr|A0A1B0GTT5|A0A1B0GTT5_HUMAN" 4 1114.5619 2.03 46978 12764 2 1114.562929 558.2882 Vimentin OS=Homo sapiens OX=9606 GN=VIM PE=1 SV=4 4.14 2473 - 1.54E+06 - - - 0.9663 - 1.786 0.271 - 270.5 1 2 0 0.0011 9 0 0 0 1.60E+08 7.86E+07 - - - 2.7202 0.9999 221125_WJC_METTL3_EV_vs_WT_F04.12765.12765.3 8.15E-05 Oct-40 K.SFSHSFSALAK.F sp|Q09161|NCBP1_HUMAN 1 1180.5877 1.12 46979 12765 3 1180.58753 394.5365 Nuclear cap-binding protein subunit 1 OS=Homo sapiens OX=9606 GN=NCBP1 PE=1 SV=1 8.49 2473.1 - 331258 - - - -0.1211 - 1.703 0.432 - 99.4 1 2 0 -0.0001 11 0 0 0 3.71E+06 3.30E+06 - - - 4.8688 0.9992 221125_WJC_METTL3_EV_vs_WT_F04.12766.12766.2 0.027 16-Aug R.SLYGLGGSK.R "sp|P48668|K2C6C_HUMAN,sp|P04259|K2C6B_HUMAN,sp|P02538|K2C6A_HUMAN" 3 880.4654 3.02 46980 12766 2 880.465909 441.24 "Keratin, type II cytoskeletal 6C OS=Homo sapiens OX=9606 GN=KRT6C PE=1 SV=3" 8.31 2473.2 - 4.39E+06 - - - 0.5418 - 1.612 0.31 - 176.2 1 2 0 0.0005 9 0 0 0 4.30E+07 1.42E+07 - - - 2.7119 0.9987 221125_WJC_METTL3_EV_vs_WT_F04.12767.12767.2 0.00506 18-Sep K.VQSLQTALEK.T "sp|Q13948|CASP_HUMAN,sp|P39880|CUX1_HUMAN,tr|A0A2R8Y8D0|A0A2R8Y8D0_HUMAN,tr|A0A2R8Y852|A0A2R8Y852_HUMAN,tr|A0A2R8YDI1|A0A2R8YDI1_HUMAN" 5 1115.6186 1.36 46981 12767 2 1115.620729 558.8166 Protein CASP OS=Homo sapiens OX=9606 GN=CUX1 PE=1 SV=2 5.97 2473.2 - 1.54E+06 - - - 1.8734 - 1.928 0.261 - 337.4 1 2 0 0.0021 10 0 0 0 1.24E+07 9.14E+06 - - - 2.8005 0.9998 221125_WJC_METTL3_EV_vs_WT_F04.12772.12772.3 0.00326 Oct-44 R.VLQQFADNDVSR[166.11].F "sp|P51659|DHB4_HUMAN,tr|A0A2R8Y7L2|A0A2R8Y7L2_HUMAN,tr|A0A2R8YD50|A0A2R8YD50_HUMAN,tr|A0A804HIR1|A0A804HIR1_HUMAN,tr|E7ET17|E7ET17_HUMAN,tr|E7EPL9|E7EPL9_HUMAN,tr|A0A804HKU2|A0A804HKU2_HUMAN,tr|A0A804HK65|A0A804HK65_HUMAN" 8 1400.6924 0.5 46986 12772 3 1400.693712 467.9047 Peroxisomal multifunctional enzyme type 2 OS=Homo sapiens OX=9606 GN=HSD17B4 PE=1 SV=3 4.21 2473.8 - 201994 - - - 0.9631 - 2.021 0.381 - 121.7 1 2 0 0.0013 12 0 0 0 1.03E+06 2.04E+06 - - - 4.7377 0.9997 221125_WJC_METTL3_EV_vs_WT_F04.12773.12773.2 0.00358 24-Sep K.QTLQSEQPLQVAR.C "sp|P35998|PRS7_HUMAN,tr|C9JX88|C9JX88_HUMAN,tr|C9JLS9|C9JLS9_HUMAN" 3 1496.7947 0.6 46987 12773 2 1496.793022 749.4046 26S proteasome regulatory subunit 7 OS=Homo sapiens OX=9606 GN=PSMC2 PE=1 SV=3 6 2474 - 198236 - - - -1.1251 - 2.246 0.394 - 298.5 1 2 0 -0.0017 13 0 0 0 1.94E+06 3.23E+06 - - - 4.0273 0.9997 221125_WJC_METTL3_EV_vs_WT_F04.12774.12774.2 0.000156 30-Sep R.LPVAC[160.03]PNQC[160.03]GVGTVAR[166.11].E "sp|Q9BUZ4|TRAF4_HUMAN,tr|F6SA91|F6SA91_HUMAN" 2 1707.8424 6.4 46988 12774 2 1707.844933 854.9285 TNF receptor-associated factor 4 OS=Homo sapiens OX=9606 GN=TRAF4 PE=1 SV=1 8.07 2474.1 - 151897 - - - 1.4744 - 2.056 0.479 - 207.5 1 2 0 0.0025 16 0 0 0 9.05E+06 1.41E+06 - - - 4.3501 0.9998 221125_WJC_METTL3_EV_vs_WT_F04.12778.12778.2 9.88E-05 18-Nov K.NHEEEMLALR.G "sp|P08779|K1C16_HUMAN,tr|K7ENW6|K7ENW6_HUMAN" 2 1240.587 7475.59 46990 12778 2 1240.588882 621.3008 "Keratin, type I cytoskeletal 16 OS=Homo sapiens OX=9606 GN=KRT16 PE=1 SV=4" 4.75 2474.5 - 2.14E+06 - - - 1.5001 - 2.358 0.498 - 543.9 1 2 0 0.0019 10 0 0 0 6.71E+08 8.97E+04 - - - 5.1131 0.9998 221125_WJC_METTL3_EV_vs_WT_F04.12779.12779.2 5.73E-06 22-Dec R.NVEDLSGGELQR[166.11].F "sp|P61221|ABCE1_HUMAN,tr|D6R9I9|D6R9I9_HUMAN" 2 1325.6451 0.81 46991 12779 2 1325.647209 663.8298 ATP-binding cassette sub-family E member 1 OS=Homo sapiens OX=9606 GN=ABCE1 PE=1 SV=1 4.14 2474.6 - 1.41E+06 - - - 1.6075 - 2.605 0.487 - 416.4 1 2 0 0.0021 12 0 0 0 1.49E+07 1.84E+07 - - - 5.1565 0.9998 221125_WJC_METTL3_EV_vs_WT_F04.12780.12780.3 0.038 Nov-36 K.FYEEVHDLER.K "sp|P55209|NP1L1_HUMAN,sp|Q99733|NP1L4_HUMAN,tr|F8VUX1|F8VUX1_HUMAN,tr|F8W543|F8W543_HUMAN,tr|A8MXH2|A8MXH2_HUMAN,tr|F8W118|F8W118_HUMAN,tr|F8VRJ2|F8VRJ2_HUMAN,tr|F8W0J6|F8W0J6_HUMAN,tr|F8VV59|F8VV59_HUMAN,tr|C9J6D1|C9J6D1_HUMAN,tr|B7Z9C2|B7Z9C2_HUMAN,tr|F8VXI6|F8VXI6_HUMAN,tr|H0YHC3|H0YHC3_HUMAN,tr|H0YIV4|H0YIV4_HUMAN,tr|F5H4R6|F5H4R6_HUMAN,tr|H0YH88|H0YH88_HUMAN,tr|F8W020|F8W020_HUMAN,tr|E9PJJ2|E9PJJ2_HUMAN,tr|E9PNW0|E9PNW0_HUMAN,tr|E9PKT8|E9PKT8_HUMAN,tr|E9PS34|E9PS34_HUMAN,tr|F8VVB5|F8VVB5_HUMAN,tr|C9JZI7|C9JZI7_HUMAN,tr|E9PNJ7|E9PNJ7_HUMAN,tr|F8VY35|F8VY35_HUMAN" 25 1335.6095 1.12 46992 12780 3 1335.609786 446.2105 Nucleosome assembly protein 1-like 1 OS=Homo sapiens OX=9606 GN=NAP1L1 PE=1 SV=1 4.4 2474.7 - 1.84E+06 - - - 0.1909 - 2.174 0.336 - 123.4 1 2 0 0.0003 10 0 0 0 3.78E+07 3.38E+07 - - - 4.5539 0.9996 221125_WJC_METTL3_EV_vs_WT_F04.12781.12781.2 0.000715 22-Dec K.NLSPGAVESDVR[166.11].G "sp|P53621|COPA_HUMAN,tr|A0A3B3ISC6|A0A3B3ISC6_HUMAN,tr|A0A3B3ITV3|A0A3B3ITV3_HUMAN,tr|A0A3B3IU78|A0A3B3IU78_HUMAN,tr|A0A3B3IS84|A0A3B3IS84_HUMAN,tr|A0A3B3ISK1|A0A3B3ISK1_HUMAN,tr|A0A3B3IT15|A0A3B3IT15_HUMAN" 7 1252.6287 0.09 46993 12781 2 1252.632045 627.3216 Coatomer subunit alpha OS=Homo sapiens OX=9606 GN=COPA PE=1 SV=2 4.37 2474.8 - 1.61E+06 - - - 2.6704 - 2.397 0.527 - 602 1 2 0 0.0033 12 0 0 0 1.35E+06 1.58E+07 - - - 5.2326 1 221125_WJC_METTL3_EV_vs_WT_F04.12782.12782.2 2.58E-07 13/22 R.NDASEVVLAGER.L "sp|Q96T88|UHRF1_HUMAN,tr|A0A087WWG9|A0A087WWG9_HUMAN,tr|A0A087WTW0|A0A087WTW0_HUMAN,tr|A0A087WVR3|A0A087WVR3_HUMAN" 4 1258.6153 1.98 46994 12782 2 1258.61407 630.3149 E3 ubiquitin-protein ligase UHRF1 OS=Homo sapiens OX=9606 GN=UHRF1 PE=1 SV=1 4.14 2474.8 - 987840 - - - -1.0122 - 2.743 0.602 - 837.2 1 2 0 -0.0013 12 0 0 0 6.52E+06 3.29E+06 - - - 6.142 0.9997 221125_WJC_METTL3_EV_vs_WT_F04.12784.12784.3 0.00598 16/36 K.LSPWIR[166.11]PDSK[136.11].V "sp|O14744|ANM5_HUMAN,tr|C9JSX3|C9JSX3_HUMAN,tr|G3V580|G3V580_HUMAN,tr|G3V2L6|G3V2L6_HUMAN,tr|G3V2X6|G3V2X6_HUMAN,tr|G3V5L5|G3V5L5_HUMAN" 6 1215.6731 2.44 46996 12784 3 1215.675659 406.2316 Protein arginine N-methyltransferase 5 OS=Homo sapiens OX=9606 GN=PRMT5 PE=1 SV=4 8.75 2475 - 836095 - - - 2.1239 - 2.575 0.327 - 305.7 1 2 0 0.0026 10 0 0 0 3.89E+08 1.59E+08 - - - 4.9473 0.9998 221125_WJC_METTL3_EV_vs_WT_F04.12786.12786.2 0.00153 24-Dec R.AGLNC[160.03]STENMPIK.L "sp|P05198|IF2A_HUMAN,tr|H0YJS4|H0YJS4_HUMAN,tr|G3V4T5|G3V4T5_HUMAN" 3 1433.6643 1.26 46998 12786 2 1433.664728 717.8394 Eukaryotic translation initiation factor 2 subunit 1 OS=Homo sapiens OX=9606 GN=EIF2S1 PE=1 SV=3 6.04 2475.3 - 416045 - - - 0.309 - 2.379 0.388 - 504.3 1 2 0 0.0004 13 0 0 0 9.87E+06 7.82E+06 - - - 4.131 0.9986 221125_WJC_METTL3_EV_vs_WT_F04.12787.12787.3 0.00397 Oct-56 K.LIEGGAHIYVC[160.03]GDAR.N "sp|P16435|NCPR_HUMAN,tr|E7EMD0|E7EMD0_HUMAN" 2 1629.7933 0.82 46999 12787 3 1629.793398 544.2717 NADPH--cytochrome P450 reductase OS=Homo sapiens OX=9606 GN=POR PE=1 SV=2 5.32 2475.4 - 264712 - - - 0.0442 - 1.635 0.293 - 127.9 1 2 0 0.0001 15 0 0 0 2.01E+06 2.44E+06 - - - 3.0895 0.9998 221125_WJC_METTL3_EV_vs_WT_F04.12788.12788.3 0.000822 13/40 R.INAGESIHIIR[166.11].G "sp|Q9Y4B4|ARIP4_HUMAN,tr|H0Y760|H0Y760_HUMAN" 2 1231.6912 3.71 47000 12788 3 1231.693298 411.571 Helicase ARIP4 OS=Homo sapiens OX=9606 GN=RAD54L2 PE=1 SV=4 6.75 2475.5 - 264089 - - - 1.6709 - 2.23 0.356 - 164.1 1 2 0 0.0021 11 0 0 0 5.60E+06 1.51E+06 - - - 4.7868 0.9999 221125_WJC_METTL3_EV_vs_WT_F04.12790.12790.2 0.000109 14/28 K.ALESISSDQQSEMVK.E tr|A0A0C4DG68|A0A0C4DG68_HUMAN 1 1650.7771 1.4 47002 12790 2 1650.777657 826.3958 Pumilio homolog 2 (Fragment) OS=Homo sapiens OX=9606 GN=PUM2 PE=1 SV=1 4.14 2475.8 - 189774 - - - 0.358 - 2.729 0.507 - 594.7 1 2 0 0.0006 15 0 0 0 1.08E+07 7.76E+06 - - - 5.2537 1 221125_WJC_METTL3_EV_vs_WT_F04.12792.12792.2 2.20E-05 17/28 K.ALESISSDQQSEMVK[136.11].E tr|A0A0C4DG68|A0A0C4DG68_HUMAN 1 1658.7913 1.4 47004 12792 2 1658.793277 830.4029 Pumilio homolog 2 (Fragment) OS=Homo sapiens OX=9606 GN=PUM2 PE=1 SV=1 4.14 2476 - 144649 - - - 1.2123 - 3.148 0.556 - 933.6 1 2 0 0.002 15 0 0 0 1.08E+07 7.76E+06 - - - 5.9664 0.9998 221125_WJC_METTL3_EV_vs_WT_F04.12795.12795.2 0.000138 18-Sep R.YSLDPENPTK.S "sp|P18621|RL17_HUMAN,tr|A0A087WWH0|A0A087WWH0_HUMAN,tr|J3QS96|J3QS96_HUMAN,tr|J3QQT2|J3QQT2_HUMAN,tr|J3KSJ0|J3KSJ0_HUMAN,tr|A0A087WY81|A0A087WY81_HUMAN,tr|J3KRB3|J3KRB3_HUMAN,tr|J3KRX5|J3KRX5_HUMAN,tr|A0A087WXM6|A0A087WXM6_HUMAN,tr|A0A0A6YYL6|A0A0A6YYL6_HUMAN" 10 1162.5506 1 47006 12795 2 1162.552026 582.2826 60S ribosomal protein L17 OS=Homo sapiens OX=9606 GN=RPL17 PE=1 SV=3 4.37 2476.4 - 1.19E+07 - - - 1.2103 - 1.957 0.534 - 217.2 1 2 0 0.0014 10 0 0 0 2.88E+08 2.87E+08 - - - 4.8588 0.9996 221125_WJC_METTL3_EV_vs_WT_F04.12796.12796.3 0.00454 Sep-36 K.NHEEEMLALR.G "sp|P08779|K1C16_HUMAN,tr|K7ENW6|K7ENW6_HUMAN" 2 1240.587 115.65 47007 12796 3 1240.587732 414.5363 "Keratin, type I cytoskeletal 16 OS=Homo sapiens OX=9606 GN=KRT16 PE=1 SV=4" 4.75 2476.5 - 376077 - - - 0.5731 - 1.814 0.34 - 98.2 1 2 0 0.0007 10 0 0 0 4.66E+08 4.03E+06 - - - 4.0697 0.9997 221125_WJC_METTL3_EV_vs_WT_F04.12797.12797.2 0.00079 16-Oct R.QFSSSYLSR.S sp|P35527|K1C9_HUMAN 1 1073.5142 -1 47008 12797 2 1073.515566 537.7644 "Keratin, type I cytoskeletal 9 OS=Homo sapiens OX=9606 GN=KRT9 PE=1 SV=3" 8.75 2476.6 - 1.66E+06 - - - 1.2967 - 1.998 0.428 - 565.3 1 2 0 0.0014 9 0 0 0 0.00E+00 0.00E+00 - - - 4.2042 0.8689 221125_WJC_METTL3_EV_vs_WT_F04.12799.12799.2 3.99 20-Jun R.EGSSPEGSTR[166.11]R[166.11].T "sp|Q9Y2I9|TBC30_HUMAN,tr|F8VZ81|F8VZ81_HUMAN" 2 1181.554 8.43 47010 12799 2 1181.556763 591.7843 TBC1 domain family member 30 OS=Homo sapiens OX=9606 GN=TBC1D30 PE=1 SV=2 6.24 2476.8 - 971851 - - - 2.3655 - 1.034 0.061 - 106.6 1 2 0 0.0028 11 0 0 0 8.38E+07 9.94E+06 - - - -0.4189 0.9997 221125_WJC_METTL3_EV_vs_WT_F04.12801.12801.2 1.66E-07 20-Sep K.NYQSQADIPIR[166.11].S sp|Q14966|ZN638_HUMAN 1 1313.6603 1.43 47012 12801 2 1313.663664 657.8374 Zinc finger protein 638 OS=Homo sapiens OX=9606 GN=ZNF638 PE=1 SV=2 5.84 2476.9 - 823749 - - - 2.5349 - 1.997 0.588 - 380.1 1 2 0 0.0033 11 0 0 0 9.11E+06 6.36E+06 - - - 5.254 0.9991 221125_WJC_METTL3_EV_vs_WT_F04.12802.12802.3 0.00271 Nov-40 R.INAGESIHIIR.G "sp|Q9Y4B4|ARIP4_HUMAN,tr|H0Y760|H0Y760_HUMAN" 2 1221.683 8.01 47013 12802 3 1221.686299 408.2349 Helicase ARIP4 OS=Homo sapiens OX=9606 GN=RAD54L2 PE=1 SV=4 6.75 2477.1 - 720008 - - - 2.7249 - 2.274 0.303 - 94.9 1 2 0 0.0033 11 0 0 0 1.33E+07 1.66E+06 - - - 4.2511 0.9998 221125_WJC_METTL3_EV_vs_WT_F04.12803.12803.2 0.00347 24-Sep R.VIAPNPAQLQGQR.G "sp|Q8WXI9|P66B_HUMAN,tr|A0A0U1RRM1|A0A0U1RRM1_HUMAN,tr|A0A0U1RR30|A0A0U1RR30_HUMAN" 3 1390.7681 1.98 47014 12803 2 1390.767646 696.3913 Transcriptional repressor p66-beta OS=Homo sapiens OX=9606 GN=GATAD2B PE=1 SV=1 9.72 2477.1 - 692129 - - - -0.3243 - 1.998 0.417 - 247 1 2 0 -0.0005 13 0 0 0 5.42E+08 2.74E+08 - - - 3.8972 0.9997 221125_WJC_METTL3_EV_vs_WT_F04.12804.12804.3 0.00194 Dec-44 K.ALYETELADAR[166.11]R[166.11].A "sp|P20700|LMNB1_HUMAN,tr|A0A0D9SFY5|A0A0D9SFY5_HUMAN,tr|E9PBF6|E9PBF6_HUMAN,tr|A0A0D9SFE5|A0A0D9SFE5_HUMAN" 4 1426.7319 1.02 47015 12804 3 1426.7307 476.5846 Lamin-B1 OS=Homo sapiens OX=9606 GN=LMNB1 PE=1 SV=2 4.68 2477.3 - 558365 - - - -0.8642 - 1.964 0.346 - 178.7 1 2 0 -0.0012 12 0 0 0 7.03E+06 6.89E+06 - - - 4.2682 0.9999 221125_WJC_METTL3_EV_vs_WT_F04.12805.12805.2 0.000131 18-Oct K.FYEEVHDLER.K "sp|P55209|NP1L1_HUMAN,sp|Q99733|NP1L4_HUMAN,tr|F8VUX1|F8VUX1_HUMAN,tr|F8W543|F8W543_HUMAN,tr|A8MXH2|A8MXH2_HUMAN,tr|F8W118|F8W118_HUMAN,tr|F8VRJ2|F8VRJ2_HUMAN,tr|F8W0J6|F8W0J6_HUMAN,tr|F8VV59|F8VV59_HUMAN,tr|C9J6D1|C9J6D1_HUMAN,tr|B7Z9C2|B7Z9C2_HUMAN,tr|F8VXI6|F8VXI6_HUMAN,tr|H0YHC3|H0YHC3_HUMAN,tr|H0YIV4|H0YIV4_HUMAN,tr|F5H4R6|F5H4R6_HUMAN,tr|H0YH88|H0YH88_HUMAN,tr|F8W020|F8W020_HUMAN,tr|E9PJJ2|E9PJJ2_HUMAN,tr|E9PNW0|E9PNW0_HUMAN,tr|E9PKT8|E9PKT8_HUMAN,tr|E9PS34|E9PS34_HUMAN,tr|F8VVB5|F8VVB5_HUMAN,tr|C9JZI7|C9JZI7_HUMAN,tr|E9PNJ7|E9PNJ7_HUMAN,tr|F8VY35|F8VY35_HUMAN" 25 1335.6095 1.02 47016 12805 2 1335.608288 668.812 Nucleosome assembly protein 1-like 1 OS=Homo sapiens OX=9606 GN=NAP1L1 PE=1 SV=1 4.4 2477.4 - 485173 - - - -0.9307 - 2.155 0.59 - 421.3 1 2 0 -0.0012 10 0 0 0 4.36E+06 4.27E+06 - - - 5.5415 1 221125_WJC_METTL3_EV_vs_WT_F04.12807.12807.2 1.57E-07 15/26 K.DVNLASC[160.03]AADGSVK.L sp|O43172|PRP4_HUMAN 1 1405.6507 3.93 47018 12807 2 1405.648964 703.8326 U4\U6 small nuclear ribonucleoprotein Prp4 OS=Homo sapiens OX=9606 GN=PRPF4 PE=1 SV=2 4.21 2477.7 - 426921 - - - -1.2663 - 3.046 0.652 - 786 1 2 0 -0.0018 14 0 0 0 1.67E+07 4.25E+06 - - - 6.6512 0.9776 221125_WJC_METTL3_EV_vs_WT_F04.12808.12808.2 1.09 16-Aug K.SVNFDMTSK.F sp|Q8WUM4|PDC6I_HUMAN 1 1027.4644 0.76 47019 12808 2 1027.465009 514.7395 Programmed cell death 6-interacting protein OS=Homo sapiens OX=9606 GN=PDCD6IP PE=1 SV=1 5.55 2477.8 - 412475 - - - 0.548 - 1.003 0.149 - 110.7 1 2 0 0.0006 9 0 0 0 5.10E+06 6.71E+06 - - - 0.15 0.9995 221125_WJC_METTL3_EV_vs_WT_F04.12809.12809.3 0.0077 Sep-32 K.YHTEIVFAR[166.11].T sp|P05023|AT1A1_HUMAN 1 1144.5905 0.09 47020 12809 3 1144.590635 382.5374 Sodium\potassium-transporting ATPase subunit alpha-1 OS=Homo sapiens OX=9606 GN=ATP1A1 PE=1 SV=1 6.75 2477.9 - 376865 - - - 0.1494 - 1.875 0.299 - 169.1 1 2 0 0.0002 9 0 0 0 2.58E+05 2.73E+06 - - - 3.768 0.9967 221125_WJC_METTL3_EV_vs_WT_F04.12812.12812.3 1.84E-05 16/52 A.SIYLHDQNPDAALR[166.11].A "sp|O14579|COPE_HUMAN,tr|M0QXB4|M0QXB4_HUMAN" 2 1621.8088 0.001 47023 12812 3 1621.809306 541.6102 Coatomer subunit epsilon OS=Homo sapiens OX=9606 GN=COPE PE=1 SV=3 5.19 2478.3 - 276556 - - - 0.3188 - 2.205 0.519 - 281.4 1 1 0 0.0005 14 0 0 0 0.00E+00 1.75E+06 - - - 6.4276 0.9896 221125_WJC_METTL3_EV_vs_WT_F04.12813.12813.2 0.274 14-Jul R.TFQFQPSK[136.11].S "sp|Q8WTV0|SCRB1_HUMAN,tr|B7ZKQ9|B7ZKQ9_HUMAN,tr|F5H4X0|F5H4X0_HUMAN,tr|F5H5E8|F5H5E8_HUMAN,tr|A0A0S2Z3I2|A0A0S2Z3I2_HUMAN,tr|A0A7P0T9B3|A0A7P0T9B3_HUMAN,tr|A0A7P0Z4E3|A0A7P0Z4E3_HUMAN,tr|A0A7P0T913|A0A7P0T913_HUMAN,tr|A0A7P0T9I2|A0A7P0T9I2_HUMAN" 9 989.5062 1.09 47024 12813 2 989.506543 495.7604 Scavenger receptor class B member 1 OS=Homo sapiens OX=9606 GN=SCARB1 PE=1 SV=1 8.41 2478.4 - 270221 - - - 0.3648 - 1.069 0.188 - 169.6 1 2 0 0.0004 8 0 0 0 2.93E+06 2.70E+06 - - - 0.6307 0.9837 221125_WJC_METTL3_EV_vs_WT_F04.12814.12814.2 0.338 18-May K.AQALC[160.03]SWTAK.K "sp|Q9NZM3|ITSN2_HUMAN,tr|A0A087WVF7|A0A087WVF7_HUMAN" 2 1134.5492 0.33 47025 12814 2 1134.55125 568.2819 Intersectin-2 OS=Homo sapiens OX=9606 GN=ITSN2 PE=1 SV=3 8.27 2478.5 - 253362 - - - 1.8254 - 1.184 0.208 - 49.4 4 2 0 0.0021 10 0 0 0 2.09E+06 6.31E+06 - - - 0.7791 0.958 221125_WJC_METTL3_EV_vs_WT_F04.12817.12817.2 4.29 26-Aug R.GTALGSVPGGSITK.G "sp|Q9Y618|NCOR2_HUMAN,tr|C9JQE8|C9JQE8_HUMAN,tr|C9J7T7|C9J7T7_HUMAN,tr|C9JE98|C9JE98_HUMAN,tr|C9J0Q5|C9J0Q5_HUMAN,tr|A0A384DVL6|A0A384DVL6_HUMAN" 6 1243.6772 2.16 47027 12817 2 1243.678209 622.8459 Nuclear receptor corepressor 2 OS=Homo sapiens OX=9606 GN=NCOR2 PE=1 SV=3 8.75 2478.9 - 523818 - - - 0.7984 - 1.166 0.05 - 119 1 2 0 0.001 14 0 0 0 1.34E+07 6.21E+06 - - - -0.2046 0.9997 221125_WJC_METTL3_EV_vs_WT_F04.12818.12818.2 3.15E-06 20-Oct K.NYQSQADIPIR.S sp|Q14966|ZN638_HUMAN 1 1303.6521 1.43 47028 12818 2 1303.653528 652.8333 Zinc finger protein 638 OS=Homo sapiens OX=9606 GN=ZNF638 PE=1 SV=2 5.84 2479 - 1.54E+06 - - - 1.123 - 2.024 0.425 - 468.9 1 2 0 0.0015 11 0 0 0 9.11E+06 6.36E+06 - - - 4.087 0.9911 221125_WJC_METTL3_EV_vs_WT_F04.12819.12819.2 3.04E-05 16-Nov R.VIHLSNLPH.S "sp|P43243|MATR3_HUMAN,tr|B3KM87|B3KM87_HUMAN,tr|A8MXP9|A8MXP9_HUMAN,tr|D6RBK5|D6RBK5_HUMAN,tr|A0A0R4J2E8|A0A0R4J2E8_HUMAN,tr|H0Y8T4|H0Y8T4_HUMAN,tr|D6REM6|D6REM6_HUMAN" 7 1028.5767 - 47029 12819 2 1028.577912 515.2956 Matrin-3 OS=Homo sapiens OX=9606 GN=MATR3 PE=1 SV=2 6.89 2479.1 - 1.42E+06 - - - 1.1647 - 2.125 0.529 - 437.3 1 1 0 0.0012 9 0 0 0 - - - - - 5.1285 1 221125_WJC_METTL3_EV_vs_WT_F04.12820.12820.2 4.88E-06 13/22 R.INDALSC[160.03]EYEC[160.03]R.R sp|Q52LJ0|FA98B_HUMAN 1 1528.6286 1.53 47030 12820 2 1528.627277 765.3216 Protein FAM98B OS=Homo sapiens OX=9606 GN=FAM98B PE=1 SV=2 4.14 2479.1 - 1.29E+06 - - - -0.8838 - 2.813 0.627 - 636.4 1 2 0 -0.0014 12 0 0 0 1.02E+07 6.65E+06 - - - 6.3929 0.9993 221125_WJC_METTL3_EV_vs_WT_F04.12822.12822.2 0.294 12-Sep K.K[136.11]LQFSLK[136.11].K "sp|P20290|BTF3_HUMAN,tr|A0A7I2V3T6|A0A7I2V3T6_HUMAN,tr|A0A7I2YQL2|A0A7I2YQL2_HUMAN" 3 878.556 0.87 47032 12822 2 878.556589 440.2853 Transcription factor BTF3 OS=Homo sapiens OX=9606 GN=BTF3 PE=1 SV=1 10 2479.3 - 1.24E+06 - - - 0.626 - 2.052 0.204 - 298.5 1 2 0 0.0006 7 0 0 0 5.61E+06 6.43E+06 - - - 2.8252 1 221125_WJC_METTL3_EV_vs_WT_F04.12823.12823.2 7.58E-07 13/22 R.INDALSC[160.03]EYEC[160.03]R[166.11].R sp|Q52LJ0|FA98B_HUMAN 1 1538.6369 1.53 47033 12823 2 1538.637439 770.3257 Protein FAM98B OS=Homo sapiens OX=9606 GN=FAM98B PE=1 SV=2 4.14 2479.4 - 1.20E+06 - - - 0.3516 - 2.602 0.667 - 577.7 1 2 0 0.0005 12 0 0 0 1.02E+07 6.65E+06 - - - 6.4834 0.9999 221125_WJC_METTL3_EV_vs_WT_F04.12824.12824.2 0.000117 13/24 R.AGLNC[160.03]STENMPIK[136.11].L "sp|P05198|IF2A_HUMAN,tr|H0YJS4|H0YJS4_HUMAN,tr|G3V4T5|G3V4T5_HUMAN" 3 1441.6785 1.26 47034 12824 2 1441.67896 721.8465 Eukaryotic translation initiation factor 2 subunit 1 OS=Homo sapiens OX=9606 GN=EIF2S1 PE=1 SV=3 6.04 2479.5 - 969833 - - - 0.3295 - 2.801 0.44 - 652.1 1 2 0 0.0005 13 0 0 0 9.87E+06 7.82E+06 - - - 4.9342 0.9915 221125_WJC_METTL3_EV_vs_WT_F04.12825.12825.2 8.44E-05 16-Dec L.SPWIRPDSK.V "sp|O14744|ANM5_HUMAN,tr|C9JSX3|C9JSX3_HUMAN,tr|G3V580|G3V580_HUMAN,tr|G3V2L6|G3V2L6_HUMAN,tr|G3V2X6|G3V2X6_HUMAN,tr|G3V5L5|G3V5L5_HUMAN" 6 1084.5665 3.41 47035 12825 2 1084.567533 543.2905 Protein arginine N-methyltransferase 5 OS=Homo sapiens OX=9606 GN=PRMT5 PE=1 SV=4 8.46 2479.6 - 962941 - - - 0.9128 - 2.059 0.524 - 712.9 1 1 0 0.001 9 0 0 0 2.86E+07 8.41E+06 - - - 5.0004 0.9998 221125_WJC_METTL3_EV_vs_WT_F04.12826.12826.3 0.0173 13/44 K.TAQNHPMLVELK.N "sp|Q9Y4Z0|LSM4_HUMAN,tr|M0QXB0|M0QXB0_HUMAN,tr|V9GZ56|V9GZ56_HUMAN" 3 1379.7231 2.51 47036 12826 3 1379.723065 460.915 U6 snRNA-associated Sm-like protein LSm4 OS=Homo sapiens OX=9606 GN=LSM4 PE=1 SV=1 6.41 2479.7 - 820320 - - - -0.0406 - 2.017 0.358 - 218.1 1 2 0 -0.0001 12 0 0 0 4.61E+07 1.84E+07 - - - 4.4761 0.9861 221125_WJC_METTL3_EV_vs_WT_F04.12827.12827.2 0.0109 14-Oct S.PWIR[166.11]PDSK[136.11].V "sp|O14744|ANM5_HUMAN,sp|Q00266|METK1_HUMAN,sp|P31153|METK2_HUMAN,tr|C9JSX3|C9JSX3_HUMAN,tr|G3V580|G3V580_HUMAN,tr|G3V2L6|G3V2L6_HUMAN,tr|B1ANE6|B1ANE6_HUMAN,tr|G3V2X6|G3V2X6_HUMAN,tr|G3V5L5|G3V5L5_HUMAN" 9 1015.557 3.63 47037 12827 2 1015.558497 508.7858 Protein arginine N-methyltransferase 5 OS=Homo sapiens OX=9606 GN=PRMT5 PE=1 SV=4 9.18 2479.8 - 786881 - - - 1.4888 - 2.295 0.419 - 601 1 1 0 0.0015 8 0 0 0 4.78E+07 1.32E+07 - - - 4.6407 1 221125_WJC_METTL3_EV_vs_WT_F04.12828.12828.2 1.40E-06 17/26 K.DVNLASC[160.03]AADGSVK[136.11].L sp|O43172|PRP4_HUMAN 1 1413.6649 3.62 47038 12828 2 1413.662826 707.8397 U4\U6 small nuclear ribonucleoprotein Prp4 OS=Homo sapiens OX=9606 GN=PRPF4 PE=1 SV=2 4.21 2480 - 587498 - - - -1.4982 - 2.944 0.59 - 1161.8 1 2 0 -0.0021 14 0 0 0 1.54E+07 4.25E+06 - - - 6.1077 0.9999 221125_WJC_METTL3_EV_vs_WT_F04.12829.12829.2 0.000198 13/22 K.NLSPGAVESDVR.G "sp|P53621|COPA_HUMAN,tr|A0A3B3ISC6|A0A3B3ISC6_HUMAN,tr|A0A3B3ITV3|A0A3B3ITV3_HUMAN,tr|A0A3B3IU78|A0A3B3IU78_HUMAN,tr|A0A3B3IS84|A0A3B3IS84_HUMAN,tr|A0A3B3ISK1|A0A3B3ISK1_HUMAN,tr|A0A3B3IT15|A0A3B3IT15_HUMAN" 7 1242.6204 0.14 47039 12829 2 1242.621874 622.3175 Coatomer subunit alpha OS=Homo sapiens OX=9606 GN=COPA PE=1 SV=2 4.37 2480.1 - 523818 - - - 1.1621 - 2.595 0.543 - 723.2 1 2 0 0.0014 12 0 0 0 3.45E+06 2.43E+07 - - - 5.5602 0.9999 221125_WJC_METTL3_EV_vs_WT_F04.12831.12831.3 0.000804 Dec-36 R.ESLMQFSK[136.11]PR[166.11].K sp|Q92900|RENT1_HUMAN 1 1239.6401 2.59 47041 12831 3 1239.640299 414.2206 Regulator of nonsense transcripts 1 OS=Homo sapiens OX=9606 GN=UPF1 PE=1 SV=2 8.85 2480.3 - 418887 - - - 0.1904 - 2.192 0.406 - 184.5 1 2 0 0.0002 10 0 0 0 1.07E+07 4.13E+06 - - - 5.3584 0.9527 221125_WJC_METTL3_EV_vs_WT_F04.12832.12832.2 4.28 14-Jun R.TFQFQPSK.S "sp|Q8WTV0|SCRB1_HUMAN,tr|B7ZKQ9|B7ZKQ9_HUMAN,tr|F5H4X0|F5H4X0_HUMAN,tr|F5H5E8|F5H5E8_HUMAN,tr|A0A0S2Z3I2|A0A0S2Z3I2_HUMAN,tr|A0A7P0T9B3|A0A7P0T9B3_HUMAN,tr|A0A7P0Z4E3|A0A7P0Z4E3_HUMAN,tr|A0A7P0T913|A0A7P0T913_HUMAN,tr|A0A7P0T9I2|A0A7P0T9I2_HUMAN" 9 981.492 0.9 47042 12832 2 981.492431 491.7533 Scavenger receptor class B member 1 OS=Homo sapiens OX=9606 GN=SCARB1 PE=1 SV=1 8.41 2480.4 - 361511 - - - 0.4575 - 0.945 0.105 - 129 1 2 0 0.0004 8 0 0 0 2.93E+06 3.25E+06 - - - -0.3542 0.9996 221125_WJC_METTL3_EV_vs_WT_F04.12834.12834.2 0.0113 20-Nov K.EAALSTALSEK.R "sp|P02545|LMNA_HUMAN,tr|A0A6Q8PF80|A0A6Q8PF80_HUMAN,tr|A0A804HL68|A0A804HL68_HUMAN,tr|Q5TCI8|Q5TCI8_HUMAN,tr|A0A6Q8PFJ0|A0A6Q8PFJ0_HUMAN,tr|A0A6Q8PHQ9|A0A6Q8PHQ9_HUMAN,tr|A0A6Q8PGH0|A0A6Q8PGH0_HUMAN,tr|Q3BDU5|Q3BDU5_HUMAN" 8 1118.5819 4.19 47044 12834 2 1118.581595 560.2982 Prelamin-A\C OS=Homo sapiens OX=9606 GN=LMNA PE=1 SV=1 4.53 2480.7 - 342424 - - - -0.2897 - 1.994 0.33 - 337 1 2 0 -0.0003 11 0 0 0 3.17E+06 7.57E+05 - - - 3.3453 0.9999 221125_WJC_METTL3_EV_vs_WT_F04.12835.12835.2 9.11E-07 18-Oct R.NDWTNPEINK[136.11].A "sp|O43402|EMC8_HUMAN,tr|M0R1B0|M0R1B0_HUMAN" 2 1237.5819 1.66 47045 12835 2 1237.582367 619.7982 ER membrane protein complex subunit 8 OS=Homo sapiens OX=9606 GN=EMC8 PE=1 SV=1 4.37 2480.8 - 271174 - - - 0.4048 - 2.179 0.541 - 415.7 1 2 0 0.0005 10 0 0 0 2.81E+06 1.69E+06 - - - 5.2107 0.9998 221125_WJC_METTL3_EV_vs_WT_F04.12842.12842.2 0.000153 13/20 R.TGVVYQIEGSK.A "sp|Q8WVQ1|CANT1_HUMAN,tr|K7EN15|K7EN15_HUMAN" 2 1179.6136 1.09 47051 12842 2 1179.615546 590.8141 Soluble calcium-activated nucleotidase 1 OS=Homo sapiens OX=9606 GN=CANT1 PE=1 SV=1 5.66 2481.5 - 1.33E+06 - - - 1.6895 - 2.64 0.519 - 809.1 1 2 0 0.002 11 0 0 0 7.07E+06 6.49E+06 - - - 5.4999 0.9999 221125_WJC_METTL3_EV_vs_WT_F04.12843.12843.2 1.07E-05 13/24 R.VIAPNPAQLQGQR[166.11].G "sp|Q8WXI9|P66B_HUMAN,tr|A0A0U1RRM1|A0A0U1RRM1_HUMAN,tr|A0A0U1RR30|A0A0U1RR30_HUMAN" 3 1400.7764 1.98 47052 12843 2 1400.776734 701.3955 Transcriptional repressor p66-beta OS=Homo sapiens OX=9606 GN=GATAD2B PE=1 SV=1 9.72 2481.6 - 1.32E+06 - - - 0.262 - 2.545 0.53 - 603.9 1 2 0 0.0004 13 0 0 0 5.42E+08 2.74E+08 - - - 5.3529 0.993 221125_WJC_METTL3_EV_vs_WT_F04.12844.12844.2 9.24E-07 24-Dec Y.ALNC[160.03]VVGSQGMPK[136.11].R "sp|P17987|TCPA_HUMAN,tr|E7EQR6|E7EQR6_HUMAN,tr|E7ERF2|E7ERF2_HUMAN" 3 1367.6781 -1 47053 12844 2 1367.678166 684.8463 T-complex protein 1 subunit alpha OS=Homo sapiens OX=9606 GN=TCP1 PE=1 SV=1 8.27 2481.7 - 1.11E+06 - - - 0.0548 - 2.438 0.487 - 502.6 1 1 0 0.0001 13 0 0 0 0.00E+00 0.00E+00 - - - 4.9252 0.9998 221125_WJC_METTL3_EV_vs_WT_F04.12845.12845.2 0.000282 20-Nov R.TGVVYQIEGSK[136.11].A "sp|Q8WVQ1|CANT1_HUMAN,tr|K7EN15|K7EN15_HUMAN" 2 1187.6278 1.24 47054 12845 2 1187.626615 594.8212 Soluble calcium-activated nucleotidase 1 OS=Homo sapiens OX=9606 GN=CANT1 PE=1 SV=1 5.66 2481.8 - 983046 - - - -0.9582 - 2.197 0.481 - 552.8 1 2 0 -0.0011 11 0 0 0 7.07E+06 5.72E+06 - - - 4.7226 1 221125_WJC_METTL3_EV_vs_WT_F04.12850.12850.2 0.000156 13/22 R.SLAASSSFYGQR[166.11].N "sp|Q13724|MOGS_HUMAN,tr|A0A3B3IRK6|A0A3B3IRK6_HUMAN,tr|A0A3B3IRW2|A0A3B3IRW2_HUMAN" 3 1282.6181 0.52 47059 12850 2 1282.620144 642.3163 Mannosyl-oligosaccharide glucosidase OS=Homo sapiens OX=9606 GN=MOGS PE=1 SV=5 8.46 2482.4 - 561135 - - - 1.5663 - 2.676 0.575 - 613.9 1 2 0 0.002 12 0 0 0 3.43E+06 6.60E+06 - - - 5.8772 0.9999 221125_WJC_METTL3_EV_vs_WT_F04.12851.12851.2 9.22E-07 20-Dec R.SGEGEVSGLMR[166.11].K "sp|Q13263|TIF1B_HUMAN,tr|M0R0K9|M0R0K9_HUMAN" 2 1130.5265 0.9 47060 12851 2 1130.527378 566.2705 Transcription intermediary factor 1-beta OS=Homo sapiens OX=9606 GN=TRIM28 PE=1 SV=5 4.53 2482.5 - 546485 - - - 0.7386 - 2.378 0.552 - 698.9 1 2 0 0.0008 11 0 0 0 7.29E+06 8.14E+06 - - - 5.4612 1 221125_WJC_METTL3_EV_vs_WT_F04.12852.12852.2 4.95E-08 16/28 R.VLGTSPEAIDSAENR[166.11].F "sp|P27708|PYR1_HUMAN,tr|F8VPD4|F8VPD4_HUMAN" 2 1567.7717 0.16 47061 12852 2 1567.773711 784.8931 CAD protein OS=Homo sapiens OX=9606 GN=CAD PE=1 SV=3 4.14 2482.6 - 543390 - - - 1.2604 - 2.942 0.612 - 890.7 1 2 0 0.002 15 0 0 0 1.62E+06 1.03E+07 - - - 6.2136 0.9998 221125_WJC_METTL3_EV_vs_WT_F04.12855.12855.2 6.96E-06 24-Oct K.LDDAIEDC[160.03]TNAVK.L "sp|Q99615|DNJC7_HUMAN,tr|A0A6I8PRZ0|A0A6I8PRZ0_HUMAN,tr|A0A6I8PLE7|A0A6I8PLE7_HUMAN,tr|A0A6I8PR89|A0A6I8PR89_HUMAN,tr|A0A6I8PIK4|A0A6I8PIK4_HUMAN,tr|A0A6I8PUC2|A0A6I8PUC2_HUMAN,tr|A0A6I8PS32|A0A6I8PS32_HUMAN,tr|A0A6I8PUD4|A0A6I8PUD4_HUMAN,tr|A0A6I8PU73|A0A6I8PU73_HUMAN,tr|A0A6I8PU89|A0A6I8PU89_HUMAN" 10 1462.661 0.42 47064 12855 2 1462.65893 732.3378 DnaJ homolog subfamily C member 7 OS=Homo sapiens OX=9606 GN=DNAJC7 PE=1 SV=2 3.84 2483 - 261328 - - - -1.3975 - 2.162 0.515 - 304.9 1 2 0 -0.002 13 0 0 0 1.16E+06 2.80E+06 - - - 4.823 1 221125_WJC_METTL3_EV_vs_WT_F04.12858.12858.3 3.41E-05 15/40 R.FPGQLNADLR[166.11]K[136.11].L "sp|P04350|TBB4A_HUMAN,sp|Q9BVA1|TBB2B_HUMAN,sp|A6NNZ2|TBB8B_HUMAN,sp|P07437|TBB5_HUMAN,sp|Q13509|TBB3_HUMAN,sp|Q13885|TBB2A_HUMAN,sp|P68371|TBB4B_HUMAN,sp|Q9BUF5|TBB6_HUMAN,sp|Q3ZCM7|TBB8_HUMAN,sp|Q9H4B7|TBB1_HUMAN,tr|M0R2D3|M0R2D3_HUMAN,tr|A0A0B4J269|A0A0B4J269_HUMAN,tr|Q5ST81|Q5ST81_HUMAN,tr|Q5JP53|Q5JP53_HUMAN,tr|K7ESM5|K7ESM5_HUMAN,tr|A0A075B736|A0A075B736_HUMAN,tr|G3V2A3|G3V2A3_HUMAN,tr|Q5SQY0|Q5SQY0_HUMAN" 18 1275.7054 -1 47066 12858 3 1275.704443 426.2424 Tubulin beta-4A chain OS=Homo sapiens OX=9606 GN=TUBB4A PE=1 SV=2 8.75 2483.4 - 1.27E+06 - - - -0.7815 - 2.706 0.493 - 168.3 1 2 0 -0.001 11 0 0 0 0.00E+00 0.00E+00 - - - 6.8642 0.9999 221125_WJC_METTL3_EV_vs_WT_F04.12860.12860.2 5.16E-06 13/22 R.ALEEANADLEVK.L "sp|P02533|K1C14_HUMAN,sp|P08779|K1C16_HUMAN,sp|P19012|K1C15_HUMAN,sp|P13646|K1C13_HUMAN,tr|K7EMD9|K7EMD9_HUMAN,tr|K7ERE3|K7ERE3_HUMAN" 6 1300.6511 463.49 47068 12860 2 1300.649864 651.3328 "Keratin, type I cytoskeletal 14 OS=Homo sapiens OX=9606 GN=KRT14 PE=1 SV=4" 4 2483.6 - 4.64E+06 - - - -0.9203 - 2.796 0.476 - 533.1 1 2 0 -0.0012 12 0 0 0 1.52E+08 3.28E+05 - - - 5.2617 0.9947 221125_WJC_METTL3_EV_vs_WT_F04.12861.12861.3 0.0249 Aug-36 R.FKVEESYDLK.D sp|P29508|SPB3_HUMAN 1 1256.6289 212.29 47069 12861 3 1256.627819 419.8836 Serpin B3 OS=Homo sapiens OX=9606 GN=SERPINB3 PE=1 SV=2 4.68 2483.6 - 3.26E+06 - - - -0.8356 - 1.488 0.314 - 95.9 1 2 1 -0.001 10 0 0 0 1.30E+07 6.14E+04 - - - 3.2012 0.9999 221125_WJC_METTL3_EV_vs_WT_F04.12862.12862.3 2.79E-05 Nov-40 K.VGYELK[136.11]DEIER[166.11].K sp|Q8WWY3|PRP31_HUMAN 1 1367.7052 2.32 47070 12862 3 1367.704124 456.909 U4\U6 small nuclear ribonucleoprotein Prp31 OS=Homo sapiens OX=9606 GN=PRPF31 PE=1 SV=2 4.41 2483.7 - 2.94E+06 - - - -0.7619 - 2.229 0.52 - 236.7 1 2 1 -0.001 11 0 0 0 2.29E+08 9.87E+07 - - - 6.6143 0.993 221125_WJC_METTL3_EV_vs_WT_F04.12864.12864.2 0.000112 16-Dec L.SPWIR[166.11]PDSK[136.11].V "sp|O14744|ANM5_HUMAN,tr|C9JSX3|C9JSX3_HUMAN,tr|G3V580|G3V580_HUMAN,tr|G3V2L6|G3V2L6_HUMAN,tr|G3V2X6|G3V2X6_HUMAN,tr|G3V5L5|G3V5L5_HUMAN" 6 1102.589 3.43 47072 12864 2 1102.588021 552.3018 Protein arginine N-methyltransferase 5 OS=Homo sapiens OX=9606 GN=PRMT5 PE=1 SV=4 8.46 2483.8 - 1.22E+06 - - - -0.8997 - 2.44 0.483 - 741.4 1 1 0 -0.001 9 0 0 0 2.82E+07 8.23E+06 - - - 5.1887 0.9994 221125_WJC_METTL3_EV_vs_WT_F04.12865.12865.2 0.000556 16-Jul R.VEFMDDTSR[166.11].S sp|P62857|RS28_HUMAN 1 1108.4734 0.94 47073 12865 2 1108.47297 555.244 40S ribosomal protein S28 OS=Homo sapiens OX=9606 GN=RPS28 PE=1 SV=1 4.03 2483.9 - 947640 - - - -0.4276 - 1.744 0.302 - 202 1 2 0 -0.0005 9 0 0 0 5.00E+06 5.33E+06 - - - 2.8805 0.9999 221125_WJC_METTL3_EV_vs_WT_F04.12866.12866.3 0.000279 15/44 K.MPC[160.03]QLHQVIVAR.F sp|P17655|CAN2_HUMAN 1 1450.7537 1.75 47074 12866 3 1450.752357 484.5918 Calpain-2 catalytic subunit OS=Homo sapiens OX=9606 GN=CAPN2 PE=1 SV=6 8.02 2484 - 911853 - - - -0.9319 - 2.322 0.435 - 383.4 1 2 0 -0.0014 12 0 0 0 5.71E+06 3.26E+06 - - - 5.7245 0.9998 221125_WJC_METTL3_EV_vs_WT_F04.12867.12867.3 0.000873 Oct-44 K.MPC[160.03]QLHQVIVAR[166.11].F sp|P17655|CAN2_HUMAN 1 1460.762 1.77 47075 12867 3 1460.761419 487.9279 Calpain-2 catalytic subunit OS=Homo sapiens OX=9606 GN=CAPN2 PE=1 SV=6 8.02 2484.1 - 791173 - - - -0.3834 - 2.225 0.327 - 156.6 1 2 0 -0.0006 12 0 0 0 5.75E+06 3.26E+06 - - - 4.4024 0.9992 221125_WJC_METTL3_EV_vs_WT_F04.12868.12868.3 0.0104 Sep-36 R.K[136.11]FDQLLAEEK[136.11].A "sp|Q7Z406|MYH14_HUMAN,sp|P35580|MYH10_HUMAN,sp|P35749|MYH11_HUMAN,sp|P35579|MYH9_HUMAN,tr|A1L2Z2|A1L2Z2_HUMAN,tr|A0A0C4DFM8|A0A0C4DFM8_HUMAN" 6 1235.6733 0.89 47076 12868 3 1235.671623 412.8984 Myosin-14 OS=Homo sapiens OX=9606 GN=MYH14 PE=1 SV=2 4.68 2484.2 - 649344 - - - -1.3191 - 1.895 0.287 - 110.4 1 2 0 -0.0016 10 0 0 0 6.34E+07 7.12E+07 - - - 3.6061 1 221125_WJC_METTL3_EV_vs_WT_F04.12872.12872.2 0.000151 26-Dec K.GELEASQQQVEVYK.L "sp|Q8IWJ2|GCC2_HUMAN,tr|H7BYJ9|H7BYJ9_HUMAN" 2 1606.7839 -1 47080 12872 2 1606.781268 804.3992 GRIP and coiled-coil domain-containing protein 2 OS=Homo sapiens OX=9606 GN=GCC2 PE=1 SV=4 4.25 2484.7 - 327466 - - - -1.6169 - 2.888 0.567 - 513 1 2 0 -0.0026 14 0 0 0 0.00E+00 0.00E+00 - - - 5.8895 1 221125_WJC_METTL3_EV_vs_WT_F04.12874.12874.2 4.24E-07 13/28 S.SLVSGLNSSASEPAK[136.11].E "sp|Q86U44|MTA70_HUMAN,tr|F5H6D8|F5H6D8_HUMAN,tr|H0YFV6|H0YFV6_HUMAN,tr|B4DTN4|B4DTN4_HUMAN" 4 1453.7504 0.32 47082 12874 2 1453.751153 727.8825 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 5.72 2485 - 286777 - - - 0.5262 - 2.641 0.607 - 439.2 1 1 0 0.0008 15 0 0 0 1.51E+07 4.67E+07 - - - 5.9117 0.9998 221125_WJC_METTL3_EV_vs_WT_F04.12878.12878.3 0.000213 13/40 K.VGYELKDEIER.K sp|Q8WWY3|PRP31_HUMAN 1 1349.6827 2.35 47084 12878 3 1349.681329 450.9015 U4\U6 small nuclear ribonucleoprotein Prp31 OS=Homo sapiens OX=9606 GN=PRPF31 PE=1 SV=2 4.41 2485.5 - 1.07E+07 - - - -1.0128 - 2.561 0.442 - 366 1 2 1 -0.0014 11 0 0 0 2.34E+08 9.95E+07 - - - 6.139 0.9996 221125_WJC_METTL3_EV_vs_WT_F04.12879.12879.3 0.000582 Oct-44 K.TAQNHPMLVELK[136.11].N "sp|Q9Y4Z0|LSM4_HUMAN,tr|M0QXB0|M0QXB0_HUMAN,tr|V9GZ56|V9GZ56_HUMAN" 3 1387.7373 2.57 47085 12879 3 1387.736215 463.5864 U6 snRNA-associated Sm-like protein LSm4 OS=Homo sapiens OX=9606 GN=LSM4 PE=1 SV=1 6.41 2485.6 - 2.61E+06 - - - -0.797 - 2.064 0.301 - 116.4 1 2 0 -0.0011 12 0 0 0 4.57E+07 1.78E+07 - - - 3.9042 0.9998 221125_WJC_METTL3_EV_vs_WT_F04.12880.12880.3 1.50E-06 13/52 K.LLVPAAEGEDSLKK.M "sp|Q96PU8|QKI_HUMAN,tr|F5GYM3|F5GYM3_HUMAN,tr|F5GXS8|F5GXS8_HUMAN,tr|H0YG47|H0YG47_HUMAN,tr|H0YGD6|H0YGD6_HUMAN" 5 1468.8137 2.33 47086 12880 3 1468.821176 490.6118 Protein quaking OS=Homo sapiens OX=9606 GN=QKI PE=1 SV=1 4.68 2485.6 - 2.52E+06 - - - 5.083 - 2.378 0.61 - 240.2 1 2 0 0.0075 14 0 0 0 4.93E+08 2.12E+08 - - - 7.6409 1 221125_WJC_METTL3_EV_vs_WT_F04.12881.12881.2 0.000497 16/18 R.K[136.11]FDQLLAEEK[136.11].A "sp|Q7Z406|MYH14_HUMAN,sp|P35580|MYH10_HUMAN,sp|P35749|MYH11_HUMAN,sp|P35579|MYH9_HUMAN,tr|A1L2Z2|A1L2Z2_HUMAN,tr|A0A0C4DFM8|A0A0C4DFM8_HUMAN" 6 1235.6733 0.98 47087 12881 2 1235.671805 618.8439 Myosin-14 OS=Homo sapiens OX=9606 GN=MYH14 PE=1 SV=2 4.68 2485.7 - 1.92E+06 - - - -1.1718 - 3.046 0.492 - 912.2 1 2 0 -0.0014 10 0 0 0 5.93E+07 6.06E+07 - - - 5.7835 0.9997 221125_WJC_METTL3_EV_vs_WT_F04.12882.12882.2 0.0758 22-Oct K.C[160.03]YAPSAIPTPQR.T sp|Q86XN7|PRSR1_HUMAN 1 1359.6605 1.51 47088 12882 2 1359.660045 680.8375 Proline and serine-rich protein 1 OS=Homo sapiens OX=9606 GN=PROSER1 PE=1 SV=2 8.22 2485.8 - 1.70E+06 - - - -0.3501 - 1.868 0.382 - 344 1 2 0 -0.0005 12 0 0 0 9.84E+06 6.54E+06 - - - 3.5064 1 221125_WJC_METTL3_EV_vs_WT_F04.12883.12883.3 0.00858 17/52 K.LLVPAAEGEDSLK[136.11]K[136.11].M "sp|Q96PU8|QKI_HUMAN,tr|F5GYM3|F5GYM3_HUMAN,tr|F5GXS8|F5GXS8_HUMAN,tr|H0YG47|H0YG47_HUMAN,tr|H0YGD6|H0YGD6_HUMAN" 5 1484.8421 2.33 47089 12883 3 1484.840178 495.9546 Protein quaking OS=Homo sapiens OX=9606 GN=QKI PE=1 SV=1 4.68 2485.8 - 1.56E+06 - - - -1.3011 - 2.738 0.46 - 325.5 1 2 0 -0.0019 14 0 0 0 4.93E+08 2.12E+08 - - - 6.3448 0.9989 221125_WJC_METTL3_EV_vs_WT_F04.12885.12885.2 0.00509 18-Nov R.KFDQLLAEEK.A "sp|Q7Z406|MYH14_HUMAN,sp|P35580|MYH10_HUMAN,sp|P35749|MYH11_HUMAN,sp|P35579|MYH9_HUMAN,tr|A1L2Z2|A1L2Z2_HUMAN,tr|A0A0C4DFM8|A0A0C4DFM8_HUMAN" 6 1219.6449 0.98 47091 12885 2 1219.649287 610.8297 Myosin-14 OS=Homo sapiens OX=9606 GN=MYH14 PE=1 SV=2 4.68 2485.9 - 1.32E+06 - - - 3.6355 - 2.713 0.362 - 378.6 1 2 0 0.0044 10 0 0 0 5.93E+07 6.06E+07 - - - 4.4992 0.9981 221125_WJC_METTL3_EV_vs_WT_F04.12886.12886.2 0.00176 20-Oct K.VGYELKDEIER.K sp|Q8WWY3|PRP31_HUMAN 1 1349.6827 0.6 47092 12886 2 1349.683091 675.8486 U4\U6 small nuclear ribonucleoprotein Prp31 OS=Homo sapiens OX=9606 GN=PRPF31 PE=1 SV=2 4.41 2486 - 1.24E+06 - - - 0.2927 - 2.458 0.393 - 329.4 1 2 1 0.0004 11 0 0 0 3.84E+07 6.42E+07 - - - 4.3765 0.9998 221125_WJC_METTL3_EV_vs_WT_F04.12890.12890.3 0.00253 Nov-40 R.R[166.11]EPTVSSFYVK[136.11].R "sp|Q9BVI4|NOC4L_HUMAN,tr|F5H303|F5H303_HUMAN" 2 1329.7048 1.66 47096 12890 3 1329.703013 444.2422 Nucleolar complex protein 4 homolog OS=Homo sapiens OX=9606 GN=NOC4L PE=1 SV=1 8.59 2486.4 - 950593 - - - -1.3229 - 2.048 0.379 - 240.1 1 2 0 -0.0018 11 0 0 0 1.25E+07 7.51E+06 - - - 4.8015 0.9998 221125_WJC_METTL3_EV_vs_WT_F04.12891.12891.2 0.00129 22-Nov R.SLAASSSFYGQR.N "sp|Q13724|MOGS_HUMAN,tr|A0A3B3IRK6|A0A3B3IRK6_HUMAN,tr|A0A3B3IRW2|A0A3B3IRW2_HUMAN" 3 1272.6099 0.44 47097 12891 2 1272.611046 637.3122 Mannosyl-oligosaccharide glucosidase OS=Homo sapiens OX=9606 GN=MOGS PE=1 SV=5 8.46 2486.6 - 692912 - - - 0.928 - 2.261 0.497 - 416.7 1 2 0 0.0012 12 0 0 0 3.43E+06 7.78E+06 - - - 4.858 1 221125_WJC_METTL3_EV_vs_WT_F04.12892.12892.2 1.17E-08 22-Dec K.AC[160.03]FQVGTSEEMK.M "sp|P35658|NU214_HUMAN,tr|A0A0A0MSW3|A0A0A0MSW3_HUMAN,tr|A0A494BZU9|A0A494BZU9_HUMAN,tr|A0A494C1F2|A0A494C1F2_HUMAN" 4 1385.5955 1.51 47098 12892 2 1385.59423 693.805 Nuclear pore complex protein Nup214 OS=Homo sapiens OX=9606 GN=NUP214 PE=1 SV=2 4.53 2486.7 - 527283 - - - -0.9433 - 2.576 0.64 - 509.2 1 2 0 -0.0013 12 0 0 0 1.13E+07 7.47E+06 - - - 6.2573 1 221125_WJC_METTL3_EV_vs_WT_F04.12896.12896.2 1.08E-07 13/24 A.AVEEYSC[160.03]EFGSAK[136.11].Y "tr|F8VVM2|F8VVM2_HUMAN,tr|F8VWQ0|F8VWQ0_HUMAN" 2 1483.6381 0.76 47102 12896 2 1483.643226 742.8263 "Phosphate carrier protein, mitochondrial OS=Homo sapiens OX=9606 GN=SLC25A3 PE=1 SV=1" 4.25 2487.2 - 210171 - - - 3.482 - 2.722 0.618 - 545.1 1 1 0 0.0052 13 0 0 0 2.47E+07 3.25E+07 - - - 6.174 0.9964 221125_WJC_METTL3_EV_vs_WT_F04.12897.12897.2 0.11 18-Jul R.R[166.11]LPDGIGQLK[136.11].Q "sp|Q14160|SCRIB_HUMAN,tr|A0A669KB89|A0A669KB89_HUMAN,tr|A0A0G2JPP5|A0A0G2JPP5_HUMAN,tr|A0A0G2JNZ2|A0A0G2JNZ2_HUMAN,tr|A0A0G2JMS7|A0A0G2JMS7_HUMAN" 5 1113.6625 0.93 47103 12897 2 1113.661683 557.8385 Protein scribble homolog OS=Homo sapiens OX=9606 GN=SCRIB PE=1 SV=4 8.75 2487.4 - 191878 - - - -0.7453 - 1.379 0.198 - 105.2 1 2 0 -0.0008 10 0 0 0 9.97E+05 1.08E+06 - - - 1.4002 0.9989 221125_WJC_METTL3_EV_vs_WT_F04.12899.12899.2 0.0332 18-Aug R.YSLDPENPTK[136.11].S "sp|P18621|RL17_HUMAN,tr|A0A087WWH0|A0A087WWH0_HUMAN,tr|J3QS96|J3QS96_HUMAN,tr|J3QQT2|J3QQT2_HUMAN,tr|J3KSJ0|J3KSJ0_HUMAN,tr|A0A087WY81|A0A087WY81_HUMAN,tr|J3KRB3|J3KRB3_HUMAN,tr|J3KRX5|J3KRX5_HUMAN,tr|A0A087WXM6|A0A087WXM6_HUMAN,tr|A0A0A6YYL6|A0A0A6YYL6_HUMAN" 10 1170.5648 1.02 47104 12899 2 1170.566431 586.2897 60S ribosomal protein L17 OS=Homo sapiens OX=9606 GN=RPL17 PE=1 SV=3 4.37 2487.6 - 925531 - - - 1.3771 - 1.477 0.352 - 140.5 1 2 0 0.0016 10 0 0 0 2.89E+08 2.84E+08 - - - 2.729 0.9998 221125_WJC_METTL3_EV_vs_WT_F04.12901.12901.2 0.00449 15/22 R.HVFLTGPPGVGK[136.11].T "sp|Q9BSD7|NTPCR_HUMAN,tr|Q5TDF0|Q5TDF0_HUMAN" 2 1215.6855 2.24 47106 12901 2 1215.683345 608.85 Cancer-related nucleoside-triphosphatase OS=Homo sapiens OX=9606 GN=NTPCR PE=1 SV=1 8.76 2487.7 - 7.96E+06 - - - -1.808 - 2.49 0.493 - 600.9 1 2 0 -0.0022 12 0 0 0 1.52E+09 6.80E+08 - - - 5.082 0.9998 221125_WJC_METTL3_EV_vs_WT_F04.12902.12902.2 3.51E-05 20-Nov R.QPSQGPTFGIK.G "sp|P11586|C1TC_HUMAN,tr|F5H2F4|F5H2F4_HUMAN,tr|V9GZ78|V9GZ78_HUMAN,tr|V9GYY3|V9GYY3_HUMAN,tr|A0A494C1T2|A0A494C1T2_HUMAN" 5 1158.6033 1.72 47107 12902 2 1158.603172 580.3089 "C-1-tetrahydrofolate synthase, cytoplasmic OS=Homo sapiens OX=9606 GN=MTHFD1 PE=1 SV=4" 8.75 2487.8 - 2.63E+06 - - - -0.1303 - 1.936 0.493 - 421.5 1 2 0 -0.0001 11 0 0 0 8.99E+07 5.24E+07 - - - 4.4694 0.9983 221125_WJC_METTL3_EV_vs_WT_F04.12903.12903.3 0.000542 Dec-36 K.LLELDPEHQR.A sp|P13674|P4HA1_HUMAN 1 1248.6463 1.83 47108 12903 3 1248.644646 417.2227 Prolyl 4-hydroxylase subunit alpha-1 OS=Homo sapiens OX=9606 GN=P4HA1 PE=1 SV=2 4.65 2487.9 - 1.88E+06 - - - -1.2846 - 2.132 0.205 - 302.5 1 2 0 -0.0016 10 0 0 0 1.38E+08 7.51E+07 - - - 3.0361 0.9999 221125_WJC_METTL3_EV_vs_WT_F04.12905.12905.2 0.000177 20-Oct R.QPSQGPTFGIK[136.11].G "sp|P11586|C1TC_HUMAN,tr|F5H2F4|F5H2F4_HUMAN,tr|V9GZ78|V9GZ78_HUMAN,tr|V9GYY3|V9GYY3_HUMAN,tr|A0A494C1T2|A0A494C1T2_HUMAN" 5 1166.6175 1.71 47110 12905 2 1166.617481 584.316 "C-1-tetrahydrofolate synthase, cytoplasmic OS=Homo sapiens OX=9606 GN=MTHFD1 PE=1 SV=4" 8.75 2488 - 1.61E+06 - - - -0.036 - 1.873 0.509 - 369.2 1 2 0 0 11 0 0 0 8.98E+07 5.24E+07 - - - 4.4981 0.9959 221125_WJC_METTL3_EV_vs_WT_F04.12906.12906.2 0.0992 16-Jul K.TVSDLIDQK.V "sp|Q9Y262|EIF3L_HUMAN,tr|B0QY89|B0QY89_HUMAN,tr|C9K0Q7|C9K0Q7_HUMAN,tr|H7C3A0|H7C3A0_HUMAN,tr|C9JHP4|C9JHP4_HUMAN" 5 1017.5342 0.86 47111 12906 2 1017.533083 509.7744 Eukaryotic translation initiation factor 3 subunit L OS=Homo sapiens OX=9606 GN=EIF3L PE=1 SV=1 4.21 2488.1 - 1.47E+06 - - - -1.1371 - 1.343 0.208 - 109.1 1 2 0 -0.0012 9 0 0 0 9.60E+06 1.11E+07 - - - 1.4301 0.9996 221125_WJC_METTL3_EV_vs_WT_F04.12908.12908.2 1.08E-05 26-Dec K.GSLGQGTAPVLPGK[136.11].T "sp|Q13428|TCOF_HUMAN,tr|E7ETY2|E7ETY2_HUMAN,tr|H0Y8Y7|H0Y8Y7_HUMAN,tr|A0A3B3IS06|A0A3B3IS06_HUMAN,tr|A0A6I8PRA0|A0A6I8PRA0_HUMAN" 5 1288.7231 1.25 47113 12908 2 1288.72263 645.3688 Treacle protein OS=Homo sapiens OX=9606 GN=TCOF1 PE=1 SV=3 8.75 2488.3 - 794258 - - - -0.3267 - 2.09 0.308 - 292 1 2 0 -0.0004 14 0 0 0 4.03E+07 3.23E+07 - - - 3.1656 0.9998 221125_WJC_METTL3_EV_vs_WT_F04.12909.12909.2 5.53E-05 26-Dec K.GSLGQGTAPVLPGK.T "sp|Q13428|TCOF_HUMAN,tr|E7ETY2|E7ETY2_HUMAN,tr|H0Y8Y7|H0Y8Y7_HUMAN,tr|A0A3B3IS06|A0A3B3IS06_HUMAN,tr|A0A6I8PRA0|A0A6I8PRA0_HUMAN" 5 1280.7089 1.25 47114 12909 2 1280.70842 641.3617 Treacle protein OS=Homo sapiens OX=9606 GN=TCOF1 PE=1 SV=3 8.75 2488.5 - 693543 - - - -0.3365 - 2.272 0.456 - 292.7 1 2 0 -0.0004 14 0 0 0 4.03E+07 3.23E+07 - - - 4.4683 1 221125_WJC_METTL3_EV_vs_WT_F04.12911.12911.2 5.15E-06 13/24 A.AVEEYSC[160.03]EFGSAK.Y "tr|F8VVM2|F8VVM2_HUMAN,tr|F8VWQ0|F8VWQ0_HUMAN" 2 1475.6239 0.76 47116 12911 2 1475.624619 738.8192 "Phosphate carrier protein, mitochondrial OS=Homo sapiens OX=9606 GN=SLC25A3 PE=1 SV=1" 4.25 2488.7 - 504619 - - - 0.5144 - 2.546 0.643 - 504.1 1 1 0 0.0008 13 0 0 0 2.47E+07 3.25E+07 - - - 6.1884 0.9996 221125_WJC_METTL3_EV_vs_WT_F04.12912.12912.2 0.0121 16-Sep R.DFLTHVSAR[166.11].E sp|O15067|PUR4_HUMAN 1 1054.5435 1.44 47117 12912 2 1054.543279 528.279 Phosphoribosylformylglycinamidine synthase OS=Homo sapiens OX=9606 GN=PFAS PE=1 SV=4 6.74 2488.8 - 493020 - - - -0.2219 - 1.628 0.368 - 307.6 1 2 0 -0.0002 9 0 0 0 6.72E+06 4.67E+06 - - - 3.1689 0.9993 221125_WJC_METTL3_EV_vs_WT_F04.12916.12916.2 2.67E-06 18-Oct R.GGNFGFGDSR.G "sp|P22626|ROA2_HUMAN,tr|A0A024RA28|A0A024RA28_HUMAN,tr|A0A7I2V4N1|A0A7I2V4N1_HUMAN,tr|A0A7I2V4I6|A0A7I2V4I6_HUMAN,tr|A0A7I2V4S4|A0A7I2V4S4_HUMAN,tr|A0A7I2V323|A0A7I2V323_HUMAN,tr|A0A7I2V3P1|A0A7I2V3P1_HUMAN,tr|A0A7I2V3P7|A0A7I2V3P7_HUMAN" 8 1012.4363 -1 47121 12916 2 1012.434538 507.2254 Heterogeneous nuclear ribonucleoproteins A2\B1 OS=Homo sapiens OX=9606 GN=HNRNPA2B1 PE=1 SV=2 5.84 2489.4 - 207388 - - - -1.6989 - 2.007 0.31 - 416.2 1 2 0 -0.0017 10 0 0 0 0.00E+00 0.00E+00 - - - 3.2747 0.9999 221125_WJC_METTL3_EV_vs_WT_F04.12919.12919.2 2.00E-06 15/22 R.HVFLTGPPGVGK.T "sp|Q9BSD7|NTPCR_HUMAN,tr|Q5TDF0|Q5TDF0_HUMAN" 2 1207.6713 1.57 47122 12919 2 1207.672057 604.8429 Cancer-related nucleoside-triphosphatase OS=Homo sapiens OX=9606 GN=NTPCR PE=1 SV=1 8.76 2489.8 - 1.20E+07 - - - 0.5912 - 2.57 0.564 - 651.6 1 2 0 0.0007 12 0 0 0 1.00E+09 6.40E+08 - - - 5.6901 0.9999 221125_WJC_METTL3_EV_vs_WT_F04.12921.12921.2 4.10E-06 18-Nov R.GGNFGFGDSR[166.11].G "sp|P22626|ROA2_HUMAN,tr|A0A024RA28|A0A024RA28_HUMAN,tr|A0A7I2V4N1|A0A7I2V4N1_HUMAN,tr|A0A7I2V4I6|A0A7I2V4I6_HUMAN,tr|A0A7I2V4S4|A0A7I2V4S4_HUMAN,tr|A0A7I2V323|A0A7I2V323_HUMAN,tr|A0A7I2V3P1|A0A7I2V3P1_HUMAN,tr|A0A7I2V3P7|A0A7I2V3P7_HUMAN" 8 1022.4445 1.32 47124 12921 2 1022.443609 512.2295 Heterogeneous nuclear ribonucleoproteins A2\B1 OS=Homo sapiens OX=9606 GN=HNRNPA2B1 PE=1 SV=2 5.84 2489.9 - 2.12E+06 - - - -0.8988 - 2.066 0.55 - 507.1 1 2 0 -0.0009 10 0 0 0 1.87E+09 1.41E+09 - - - 5.1284 0.9997 221125_WJC_METTL3_EV_vs_WT_F04.12922.12922.3 0.00034 15/48 R.VIAPNPAQLQGQR[166.11].G "sp|Q8WXI9|P66B_HUMAN,tr|A0A0U1RRM1|A0A0U1RRM1_HUMAN,tr|A0A0U1RR30|A0A0U1RR30_HUMAN" 3 1400.7764 2.24 47125 12922 3 1400.773259 467.9327 Transcriptional repressor p66-beta OS=Homo sapiens OX=9606 GN=GATAD2B PE=1 SV=1 9.72 2489.9 - 1.88E+06 - - - -2.2188 - 2.266 0.368 - 295.6 1 2 0 -0.0031 13 0 0 0 1.07E+08 4.80E+07 - - - 4.8599 0.9997 221125_WJC_METTL3_EV_vs_WT_F04.12923.12923.3 0.309 13/36 R.LQEVFGHAIK.A "sp|P54136|SYRC_HUMAN,tr|E5RJM9|E5RJM9_HUMAN,tr|E5RH09|E5RH09_HUMAN" 3 1140.6291 1.23 47126 12923 3 1140.627753 381.217 "Arginine--tRNA ligase, cytoplasmic OS=Homo sapiens OX=9606 GN=RARS1 PE=1 SV=2" 6.75 2490 - 1.73E+06 - - - -1.2195 - 2.288 0.308 - 182 1 2 0 -0.0014 10 0 0 0 2.97E+07 2.42E+07 - - - 4.3907 0.9997 221125_WJC_METTL3_EV_vs_WT_F04.12925.12925.2 9.58E-06 26-Nov K.LLVPAAEGEDSLKK.M "sp|Q96PU8|QKI_HUMAN,tr|F5GYM3|F5GYM3_HUMAN,tr|F5GXS8|F5GXS8_HUMAN,tr|H0YG47|H0YG47_HUMAN,tr|H0YGD6|H0YGD6_HUMAN" 5 1468.8137 4.37 47128 12925 2 1468.816275 735.4141 Protein quaking OS=Homo sapiens OX=9606 GN=QKI PE=1 SV=1 4.68 2490.2 - 734471 - - - 1.7463 - 2.124 0.496 - 270.5 1 2 0 0.0026 14 0 0 0 2.56E+07 5.85E+06 - - - 4.594 0.9479 221125_WJC_METTL3_EV_vs_WT_F04.12928.12928.2 0.0001 22-Nov R.RAEQDSTTVAAF.A "sp|Q86U44|MTA70_HUMAN,tr|F5H6D8|F5H6D8_HUMAN,tr|H0YFV6|H0YFV6_HUMAN,tr|B4DTN4|B4DTN4_HUMAN" 4 1294.6153 0.02 47131 12928 2 1294.618681 648.3149 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 4.37 2490.6 - 576905 - - - 2.5776 - 2.052 0.376 - 409.7 1 1 0 0.0033 12 0 0 0 2.37E+08 1.19E+10 - - - 3.7084 0.9994 221125_WJC_METTL3_EV_vs_WT_F04.12931.12931.2 0.00475 24-Sep R.LQGQITEGSNMIK.T "sp|O95251|KAT7_HUMAN,tr|A0A6Q8PHH2|A0A6Q8PHH2_HUMAN,tr|E7EUP3|E7EUP3_HUMAN" 3 1417.7235 0.84 47134 12931 2 1417.724829 709.869 Histone acetyltransferase KAT7 OS=Homo sapiens OX=9606 GN=KAT7 PE=1 SV=1 6 2491 - 333480 - - - 0.9268 - 1.81 0.344 - 279.3 1 2 0 0.0013 13 0 0 0 1.53E+06 1.83E+06 - - - 3.1042 0.9998 221125_WJC_METTL3_EV_vs_WT_F04.12932.12932.2 3.77E-06 28-Sep R.VFSANSTAAC[160.03]TELAK[136.11].R sp|Q14558|KPRA_HUMAN 1 1576.7647 0.001 47135 12932 2 1576.764899 789.3896 Phosphoribosyl pyrophosphate synthase-associated protein 1 OS=Homo sapiens OX=9606 GN=PRPSAP1 PE=1 SV=2 5.97 2491.1 - 278991 - - - 0.1528 - 2.09 0.486 - 158.5 1 2 0 0.0002 15 0 0 0 0.00E+00 2.20E+06 - - - 4.4429 1 221125_WJC_METTL3_EV_vs_WT_F04.12936.12936.2 8.95E-08 22-Nov R.R[166.11]AEQDSTTVAAF.A "sp|Q86U44|MTA70_HUMAN,tr|F5H6D8|F5H6D8_HUMAN,tr|H0YFV6|H0YFV6_HUMAN,tr|B4DTN4|B4DTN4_HUMAN" 4 1304.6236 0.02 47137 12936 2 1304.622599 653.3191 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 4.37 2491.7 - 1.04E+08 - - - -0.778 - 2.251 0.644 - 414.3 1 1 0 -0.001 12 0 0 0 2.37E+08 1.19E+10 - - - 5.9321 0.9999 221125_WJC_METTL3_EV_vs_WT_F04.12939.12939.2 0.000258 22-Dec K.VADWTGATYQDK.R "sp|O15371|EIF3D_HUMAN,tr|B0QYA8|B0QYA8_HUMAN,tr|B0QYA6|B0QYA6_HUMAN,tr|B0QYA5|B0QYA5_HUMAN" 4 1353.6201 1.3 47140 12939 2 1353.618299 677.8173 Eukaryotic translation initiation factor 3 subunit D OS=Homo sapiens OX=9606 GN=EIF3D PE=1 SV=1 4.21 2491.9 - 1.98E+06 - - - -1.3268 - 2.741 0.536 - 552 1 2 0 -0.0018 12 0 0 0 8.11E+07 6.23E+07 - - - 5.6524 0.9994 221125_WJC_METTL3_EV_vs_WT_F04.12940.12940.2 1.03E-07 20-Nov R.GC[160.03]TATLGNFAK[136.11].A "sp|P15880|RS2_HUMAN,tr|E9PQD7|E9PQD7_HUMAN,tr|H0YEN5|H0YEN5_HUMAN" 3 1146.5583 1.12 47141 12940 2 1146.554107 574.2864 40S ribosomal protein S2 OS=Homo sapiens OX=9606 GN=RPS2 PE=1 SV=2 8.22 2491.9 - 1.85E+06 - - - -3.6518 - 2.239 0.583 - 621.9 1 2 0 -0.0042 11 0 0 0 4.79E+08 4.28E+08 - - - 5.5262 0.9979 221125_WJC_METTL3_EV_vs_WT_F04.12942.12942.2 0.00327 18-Aug K.LLELDPEHQR.A sp|P13674|P4HA1_HUMAN 1 1248.6463 2.34 47143 12942 2 1248.642475 625.3304 Prolyl 4-hydroxylase subunit alpha-1 OS=Homo sapiens OX=9606 GN=P4HA1 PE=1 SV=2 4.65 2492.1 - 931986 - - - -3.0233 - 1.741 0.338 - 230.5 1 2 0 -0.0038 10 0 0 0 2.48E+07 1.06E+07 - - - 3.0839 0.9999 221125_WJC_METTL3_EV_vs_WT_F04.12951.12951.2 1.93E-05 13/24 R.IEDVTPIPSDSTR.R "sp|P62263|RS14_HUMAN,tr|A0A2R8Y811|A0A2R8Y811_HUMAN" 2 1428.7096 1.72 47150 12951 2 1428.709591 715.3621 40S ribosomal protein S14 OS=Homo sapiens OX=9606 GN=RPS14 PE=1 SV=3 4.03 2493.1 - 597674 - - - -0.0336 - 2.579 0.544 - 490.6 1 2 0 0 13 0 0 0 2.35E+07 1.37E+07 - - - 5.4905 0.9998 221125_WJC_METTL3_EV_vs_WT_F04.12953.12953.2 0.000573 26-Sep K.VQALEEANNDLENK.L sp|P35527|K1C9_HUMAN 1 1585.7584 999 47152 12953 2 1585.759724 793.8865 "Keratin, type I cytoskeletal 9 OS=Homo sapiens OX=9606 GN=KRT9 PE=1 SV=3" 4 2493.4 - 390608 - - - 0.8475 - 1.978 0.485 - 124.4 1 2 0 0.0013 14 0 0 0 3.72E+06 0.00E+00 - - - 4.3344 0.9778 221125_WJC_METTL3_EV_vs_WT_F04.12954.12954.2 0.457 28-May R.IPPPGSQPPVLNTSR.E "sp|Q5JSZ5|PRC2B_HUMAN,tr|A0A804HKU3|A0A804HKU3_HUMAN,tr|A0A804HJR4|A0A804HJR4_HUMAN" 3 1558.8467 8.53 47153 12954 2 1558.846072 780.4306 Protein PRRC2B OS=Homo sapiens OX=9606 GN=PRRC2B PE=1 SV=2 9.75 2493.5 - 336252 - - - -0.4292 - 1.06 0.153 - 22.2 3 2 0 -0.0007 15 0 0 0 4.33E+06 5.08E+05 - - - 0.101 0.9998 221125_WJC_METTL3_EV_vs_WT_F04.12957.12957.2 0.000365 20-Oct K.LDIPTGTTPQR.K "sp|P52732|KIF11_HUMAN,tr|A0A7I2V3A9|A0A7I2V3A9_HUMAN" 2 1197.6354 999 47154 12957 2 1197.634078 599.825 Kinesin-like protein KIF11 OS=Homo sapiens OX=9606 GN=KIF11 PE=1 SV=2 5.84 2493.9 - 4.29E+07 - - - -1.0629 - 1.972 0.521 - 301.9 1 2 0 -0.0013 11 0 0 0 9.57E+08 0.00E+00 - - - 4.7257 0.9998 221125_WJC_METTL3_EV_vs_WT_F04.12960.12960.2 0.000141 24-Dec R.IEDVTPIPSDSTR[166.11].R "sp|P62263|RS14_HUMAN,tr|A0A2R8Y811|A0A2R8Y811_HUMAN" 2 1438.7179 1.69 47157 12960 2 1438.716866 720.3662 40S ribosomal protein S14 OS=Homo sapiens OX=9606 GN=RPS14 PE=1 SV=3 4.03 2494.3 - 408075 - - - -0.725 - 2.086 0.428 - 336.8 1 2 0 -0.001 13 0 0 0 2.32E+07 1.37E+07 - - - 4.0889 0.9992 221125_WJC_METTL3_EV_vs_WT_F04.12965.12965.3 0.00108 Oct-36 R.LK[136.11]EEYQSLIR[166.11].Y sp|Q9Y3C8|UFC1_HUMAN 1 1295.7204 1 47160 12965 3 1295.718474 432.9141 Ubiquitin-fold modifier-conjugating enzyme 1 OS=Homo sapiens OX=9606 GN=UFC1 PE=1 SV=3 6.14 2495 - 1.12E+06 - - - -1.5034 - 1.994 0.388 - 147.4 1 2 1 -0.0019 10 0 0 0 1.70E+07 1.71E+07 - - - 4.8808 0.9999 221125_WJC_METTL3_EV_vs_WT_F04.12978.12978.3 7.68E-06 14/44 K.KLLETEC[160.03]PQYIR.K sp|P05109|S10A8_HUMAN 1 1548.797 13.07 47169 12978 3 1548.793928 517.2729 Protein S100-A8 OS=Homo sapiens OX=9606 GN=S100A8 PE=1 SV=1 6.14 2496.6 - 1.24E+06 - - - -1.9925 - 2.658 0.439 - 332.1 1 2 0 -0.0031 12 0 0 0 7.77E+07 5.94E+06 - - - 6.1433 0.9958 221125_WJC_METTL3_EV_vs_WT_F04.12981.12981.3 0.0118 Nov-48 R.LKDGSTMLIEAAK.G "sp|O75179|ANR17_HUMAN,sp|Q8IWZ3|ANKH1_HUMAN,tr|E9PDP5|E9PDP5_HUMAN,tr|H0YM23|H0YM23_HUMAN,tr|H3BLS9|H3BLS9_HUMAN,tr|A0A1W2PQ15|A0A1W2PQ15_HUMAN,tr|H7C2F5|H7C2F5_HUMAN" 7 1375.7381 0.98 47172 12981 3 1375.736074 459.5866 Ankyrin repeat domain-containing protein 17 OS=Homo sapiens OX=9606 GN=ANKRD17 PE=1 SV=3 6.07 2496.8 - 3.52E+06 - - - -1.4741 - 1.861 0.298 - 155.4 1 2 1 -0.002 13 0 0 0 1.05E+08 1.08E+08 - - - 3.5459 0.9992 221125_WJC_METTL3_EV_vs_WT_F04.12985.12985.2 9.04E-06 20-Oct R.DSLTGSSDLYK.R "sp|Q14671|PUM1_HUMAN,tr|Q5T1Z8|Q5T1Z8_HUMAN,tr|H0YDK8|H0YDK8_HUMAN,tr|Q5T1Z4|Q5T1Z4_HUMAN,tr|E9PR38|E9PR38_HUMAN" 5 1184.5561 2.29 47174 12985 2 1184.552731 593.2853 Pumilio homolog 1 OS=Homo sapiens OX=9606 GN=PUM1 PE=1 SV=3 4.21 2497.3 - 1.44E+06 - - - -2.8424 - 2.14 0.414 - 212.2 1 2 0 -0.0034 11 0 0 0 1.92E+08 8.39E+07 - - - 4.1559 0.9993 221125_WJC_METTL3_EV_vs_WT_F04.12988.12988.2 6.13E-07 20-Dec R.DSLTGSSDLYK[136.11].R "sp|Q14671|PUM1_HUMAN,tr|Q5T1Z8|Q5T1Z8_HUMAN,tr|H0YDK8|H0YDK8_HUMAN,tr|Q5T1Z4|Q5T1Z4_HUMAN,tr|E9PR38|E9PR38_HUMAN" 5 1192.5703 2.27 47177 12988 2 1192.565917 597.2924 Pumilio homolog 1 OS=Homo sapiens OX=9606 GN=PUM1 PE=1 SV=3 4.21 2497.7 - 993640 - - - -3.6736 - 2.15 0.556 - 346.4 1 2 0 -0.0044 11 0 0 0 1.92E+08 8.47E+07 - - - 5.217 0.9732 221125_WJC_METTL3_EV_vs_WT_F04.12989.12989.2 0.62 16-Oct K.IR[166.11]DILAQVK[136.11].Q sp|Q9NZI8|IF2B1_HUMAN 1 1072.6723 1.51 47178 12989 2 1072.671721 537.3435 Insulin-like growth factor 2 mRNA-binding protein 1 OS=Homo sapiens OX=9606 GN=IGF2BP1 PE=1 SV=2 8.75 2497.8 - 841745 - - - -0.5855 - 1.565 0.18 - 373.2 1 2 1 -0.0006 9 0 0 0 1.69E+07 1.12E+07 - - - 1.666 0.9992 221125_WJC_METTL3_EV_vs_WT_F04.12990.12990.2 2.32E-05 13/24 R.AIQC[160.03]VNNVVVDGR.T sp|O95628|CNOT4_HUMAN 1 1442.73 0.75 47179 12990 2 1442.724405 722.3723 CCR4-NOT transcription complex subunit 4 OS=Homo sapiens OX=9606 GN=CNOT4 PE=1 SV=3 5.87 2497.9 - 693455 - - - -3.876 - 2.721 0.528 - 614.7 1 2 0 -0.0056 13 0 0 0 3.14E+07 4.21E+07 - - - 5.5081 0.9997 221125_WJC_METTL3_EV_vs_WT_F04.12992.12992.3 0.0157 Nov-36 R.IDISPSTFRK.H "sp|Q9Y2W1|TR150_HUMAN,tr|A0A3B3ITZ9|A0A3B3ITZ9_HUMAN" 2 1162.6346 2.39 47180 12992 3 1162.633577 388.5522 Thyroid hormone receptor-associated protein 3 OS=Homo sapiens OX=9606 GN=THRAP3 PE=1 SV=2 8.75 2498.2 - 2.49E+06 - - - -0.8997 - 2.152 0.308 - 152.1 1 2 0 -0.001 10 0 0 0 1.74E+08 7.30E+07 - - - 4.2118 0.9996 221125_WJC_METTL3_EV_vs_WT_F04.12994.12994.2 0.0243 22-Aug K.ATISNDGATILK[136.11].L "sp|Q99832|TCPH_HUMAN,tr|F8WAM2|F8WAM2_HUMAN" 2 1210.6649 0.14 47181 12994 2 1210.664187 606.3397 T-complex protein 1 subunit eta OS=Homo sapiens OX=9606 GN=CCT7 PE=1 SV=2 5.88 2498.4 - 2.20E+07 - - - -0.5617 - 1.794 0.385 - 139.2 1 2 0 -0.0007 12 0 0 0 8.45E+07 6.06E+08 - - - 3.4222 0.9998 221125_WJC_METTL3_EV_vs_WT_F04.12995.12995.2 4.74E-05 22-Oct K.ATISNDGATILK.L "sp|Q99832|TCPH_HUMAN,tr|F8WAM2|F8WAM2_HUMAN" 2 1202.6507 0.14 47182 12995 2 1202.649152 602.3326 T-complex protein 1 subunit eta OS=Homo sapiens OX=9606 GN=CCT7 PE=1 SV=2 5.88 2498.4 - 3.62E+06 - - - -1.2597 - 2.249 0.462 - 219.2 1 2 0 -0.0015 12 0 0 0 8.45E+07 6.06E+08 - - - 4.5854 0.9725 221125_WJC_METTL3_EV_vs_WT_F04.12996.12996.2 2.54E-05 13/24 R.LKDGSTMLIEAAK.G "sp|O75179|ANR17_HUMAN,sp|Q8IWZ3|ANKH1_HUMAN,tr|E9PDP5|E9PDP5_HUMAN,tr|H0YM23|H0YM23_HUMAN,tr|H3BLS9|H3BLS9_HUMAN,tr|A0A1W2PQ15|A0A1W2PQ15_HUMAN,tr|H7C2F5|H7C2F5_HUMAN" 7 1375.7381 0.05 47183 12996 2 1375.744959 688.8763 Ankyrin repeat domain-containing protein 17 OS=Homo sapiens OX=9606 GN=ANKRD17 PE=1 SV=3 6.07 2498.6 - 821942 - - - 4.9842 - 2.246 0.492 - 268.7 1 2 1 0.0069 13 0 0 0 1.60E+07 3.05E+08 - - - 4.7495 0.9941 221125_WJC_METTL3_EV_vs_WT_F04.12997.12997.2 0.227 16-Nov K.IRDILAQVK.Q sp|Q9NZI8|IF2B1_HUMAN 1 1054.6499 1.51 47184 12997 2 1054.648313 528.3322 Insulin-like growth factor 2 mRNA-binding protein 1 OS=Homo sapiens OX=9606 GN=IGF2BP1 PE=1 SV=2 8.75 2498.7 - 812535 - - - -1.4849 - 2.064 0.309 - 509.4 1 2 1 -0.0016 9 0 0 0 1.69E+07 1.12E+07 - - - 3.4192 1 221125_WJC_METTL3_EV_vs_WT_F04.12999.12999.2 2.03E-09 16/26 K.VLQATVVAVGSGSK.G "sp|P61604|CH10_HUMAN,tr|S4R3N1|S4R3N1_HUMAN,tr|B8ZZL8|B8ZZL8_HUMAN" 3 1314.7507 1.03 47186 12999 2 1314.749843 658.3826 "10 kDa heat shock protein, mitochondrial OS=Homo sapiens OX=9606 GN=HSPE1 PE=1 SV=2" 8.72 2498.9 - 502472 - - - -0.664 - 2.818 0.602 - 731.6 1 2 0 -0.0009 14 0 0 0 1.97E+07 1.92E+07 - - - 6.087 0.9999 221125_WJC_METTL3_EV_vs_WT_F04.13004.13004.3 6.23E-05 14/40 K.SNFAEALAAHK.Y "sp|P07237|PDIA1_HUMAN,tr|A0A7P0TA97|A0A7P0TA97_HUMAN,tr|A0A7P0T8C0|A0A7P0T8C0_HUMAN,tr|H7BZ94|H7BZ94_HUMAN,tr|A0A7P0Z4B2|A0A7P0Z4B2_HUMAN,tr|A0A7P0TA71|A0A7P0TA71_HUMAN,tr|I3L4M2|I3L4M2_HUMAN,tr|A0A7P0T9D6|A0A7P0T9D6_HUMAN,tr|A0A7P0T9K9|A0A7P0T9K9_HUMAN,tr|H0Y3Z3|H0Y3Z3_HUMAN,tr|A0A7P0Z4S2|A0A7P0Z4S2_HUMAN,tr|I3NI03|I3NI03_HUMAN,tr|A0A7P0TA35|A0A7P0TA35_HUMAN,tr|A0A7P0TAX9|A0A7P0TAX9_HUMAN,tr|I3L1Y5|I3L1Y5_HUMAN,tr|I3L514|I3L514_HUMAN,tr|A0A7P0Z476|A0A7P0Z476_HUMAN,tr|A0A7P0Z4F8|A0A7P0Z4F8_HUMAN,tr|A0A7P0TBP8|A0A7P0TBP8_HUMAN,tr|A0A7P0TB26|A0A7P0TB26_HUMAN,tr|A0A7P0T9U6|A0A7P0T9U6_HUMAN,tr|A0A7P0T9E3|A0A7P0T9E3_HUMAN,tr|A0A7P0TBA3|A0A7P0TBA3_HUMAN,tr|I3L0S0|I3L0S0_HUMAN,tr|I3L3P5|I3L3P5_HUMAN,tr|A0A7P0T940|A0A7P0T940_HUMAN,tr|A0A7P0T8J3|A0A7P0T8J3_HUMAN,tr|A0A7P0Z4J0|A0A7P0Z4J0_HUMAN,tr|A0A7P0T9S9|A0A7P0T9S9_HUMAN,tr|A0A7P0T8X1|A0A7P0T8X1_HUMAN,tr|I3L3U6|I3L3U6_HUMAN" 31 1157.5829 1.78 47189 13004 3 1157.579268 386.8683 Protein disulfide-isomerase OS=Homo sapiens OX=9606 GN=P4HB PE=1 SV=3 6.47 2499.4 - 5.13E+06 - - - -3.1566 - 2.413 0.503 - 328.1 1 2 0 -0.0037 11 0 0 0 1.16E+08 6.48E+07 - - - 6.6493 0.9998 221125_WJC_METTL3_EV_vs_WT_F04.13005.13005.2 1.38E-05 16/24 R.AIQC[160.03]VNNVVVDGR[166.11].T sp|O95628|CNOT4_HUMAN 1 1452.7383 0.64 47190 13005 2 1452.735888 727.3764 CCR4-NOT transcription complex subunit 4 OS=Homo sapiens OX=9606 GN=CNOT4 PE=1 SV=3 5.87 2499.6 - 1.08E+06 - - - -1.6376 - 2.886 0.478 - 975.6 1 2 0 -0.0024 13 0 0 0 3.12E+07 4.89E+07 - - - 5.291 0.9661 221125_WJC_METTL3_EV_vs_WT_F04.13006.13006.2 0.00125 20-Nov L.YLANDVIQNSK.R "sp|Q96P16|RPR1A_HUMAN,sp|Q9NQG5|RPR1B_HUMAN,tr|E9PIQ9|E9PIQ9_HUMAN,tr|A0A0C4DGQ6|A0A0C4DGQ6_HUMAN" 4 1263.6459 3.37 47191 13006 2 1263.643507 632.8302 Regulation of nuclear pre-mRNA domain-containing protein 1A OS=Homo sapiens OX=9606 GN=RPRD1A PE=1 SV=1 5.83 2499.7 - 638586 - - - -1.9064 - 1.791 0.407 - 304.2 1 1 0 -0.0024 11 0 0 0 1.02E+07 3.02E+06 - - - 3.6229 0.9999 221125_WJC_METTL3_EV_vs_WT_F04.13007.13007.3 5.65E-05 13/44 R.FQDAAELAQHVR.L sp|Q9UK33|ZN580_HUMAN 1 1383.6895 0.28 47192 13007 3 1383.686082 462.2371 Zinc finger protein 580 OS=Homo sapiens OX=9606 GN=ZNF580 PE=1 SV=1 5.32 2499.8 - 493207 - - - -2.4789 - 2.239 0.485 - 187.4 1 2 0 -0.0034 12 0 0 0 8.22E+06 2.90E+07 - - - 6.1805 0.9998 221125_WJC_METTL3_EV_vs_WT_F04.13010.13010.2 0.000252 18-Oct R.SGFSSISVSR.S "sp|P48668|K2C6C_HUMAN,sp|P04259|K2C6B_HUMAN" 2 1025.5142 1725.64 47193 13010 2 1025.514049 513.7644 "Keratin, type II cytoskeletal 6C OS=Homo sapiens OX=9606 GN=KRT6C PE=1 SV=3" 9.47 2500.2 - 4.83E+07 - - - -0.1219 - 1.997 0.4 - 268.4 1 2 0 -0.0001 10 0 0 0 3.68E+09 2.13E+06 - - - 3.926 1 221125_WJC_METTL3_EV_vs_WT_F04.13012.13012.2 4.09E-11 16/30 N.LLEGGQEDFESSGAGK.L "sp|P35527|K1C9_HUMAN,tr|K7EQQ3|K7EQQ3_HUMAN" 2 1622.7424 999 47195 13012 2 1622.740226 812.3785 "Keratin, type I cytoskeletal 9 OS=Homo sapiens OX=9606 GN=KRT9 PE=1 SV=3" 4 2500.5 - 846004 - - - -1.3366 - 3.036 0.683 - 690 1 1 0 -0.0022 16 0 0 0 1.30E+07 0.00E+00 - - - 6.8153 0.9995 221125_WJC_METTL3_EV_vs_WT_F04.13016.13016.2 0.00125 20-Nov K.NSLDC[160.03]EIVSAK.S sp|Q01518|CAP1_HUMAN 1 1234.5864 2.48 47197 13016 2 1234.583468 618.3005 Adenylyl cyclase-associated protein 1 OS=Homo sapiens OX=9606 GN=CAP1 PE=1 SV=5 4.37 2501 - 793183 - - - -2.3368 - 2.11 0.445 - 484.9 1 2 0 -0.0029 11 0 0 0 2.37E+07 9.56E+06 - - - 4.3468 1 221125_WJC_METTL3_EV_vs_WT_F04.13017.13017.2 8.65E-08 13/20 K.SNFAEALAAHK.Y "sp|P07237|PDIA1_HUMAN,tr|A0A7P0TA97|A0A7P0TA97_HUMAN,tr|A0A7P0T8C0|A0A7P0T8C0_HUMAN,tr|H7BZ94|H7BZ94_HUMAN,tr|A0A7P0Z4B2|A0A7P0Z4B2_HUMAN,tr|A0A7P0TA71|A0A7P0TA71_HUMAN,tr|I3L4M2|I3L4M2_HUMAN,tr|A0A7P0T9D6|A0A7P0T9D6_HUMAN,tr|A0A7P0T9K9|A0A7P0T9K9_HUMAN,tr|H0Y3Z3|H0Y3Z3_HUMAN,tr|A0A7P0Z4S2|A0A7P0Z4S2_HUMAN,tr|I3NI03|I3NI03_HUMAN,tr|A0A7P0TA35|A0A7P0TA35_HUMAN,tr|A0A7P0TAX9|A0A7P0TAX9_HUMAN,tr|I3L1Y5|I3L1Y5_HUMAN,tr|I3L514|I3L514_HUMAN,tr|A0A7P0Z476|A0A7P0Z476_HUMAN,tr|A0A7P0Z4F8|A0A7P0Z4F8_HUMAN,tr|A0A7P0TBP8|A0A7P0TBP8_HUMAN,tr|A0A7P0TB26|A0A7P0TB26_HUMAN,tr|A0A7P0T9U6|A0A7P0T9U6_HUMAN,tr|A0A7P0T9E3|A0A7P0T9E3_HUMAN,tr|A0A7P0TBA3|A0A7P0TBA3_HUMAN,tr|I3L0S0|I3L0S0_HUMAN,tr|I3L3P5|I3L3P5_HUMAN,tr|A0A7P0T940|A0A7P0T940_HUMAN,tr|A0A7P0T8J3|A0A7P0T8J3_HUMAN,tr|A0A7P0Z4J0|A0A7P0Z4J0_HUMAN,tr|A0A7P0T9S9|A0A7P0T9S9_HUMAN,tr|A0A7P0T8X1|A0A7P0T8X1_HUMAN,tr|I3L3U6|I3L3U6_HUMAN" 31 1157.5829 1.55 47198 13017 2 1157.581037 579.7987 Protein disulfide-isomerase OS=Homo sapiens OX=9606 GN=P4HB PE=1 SV=3 6.47 2501.1 - 1.04E+06 - - - -1.6284 - 2.543 0.568 - 682.1 1 2 0 -0.0019 11 0 0 0 1.85E+07 1.19E+07 - - - 5.7606 0.9997 221125_WJC_METTL3_EV_vs_WT_F04.13019.13019.2 6.65E-07 20-Nov K.SNFAEALAAHK[136.11].Y "sp|P07237|PDIA1_HUMAN,tr|A0A7P0TA97|A0A7P0TA97_HUMAN,tr|A0A7P0T8C0|A0A7P0T8C0_HUMAN,tr|H7BZ94|H7BZ94_HUMAN,tr|A0A7P0Z4B2|A0A7P0Z4B2_HUMAN,tr|A0A7P0TA71|A0A7P0TA71_HUMAN,tr|I3L4M2|I3L4M2_HUMAN,tr|A0A7P0T9D6|A0A7P0T9D6_HUMAN,tr|A0A7P0T9K9|A0A7P0T9K9_HUMAN,tr|H0Y3Z3|H0Y3Z3_HUMAN,tr|A0A7P0Z4S2|A0A7P0Z4S2_HUMAN,tr|I3NI03|I3NI03_HUMAN,tr|A0A7P0TA35|A0A7P0TA35_HUMAN,tr|A0A7P0TAX9|A0A7P0TAX9_HUMAN,tr|I3L1Y5|I3L1Y5_HUMAN,tr|I3L514|I3L514_HUMAN,tr|A0A7P0Z476|A0A7P0Z476_HUMAN,tr|A0A7P0Z4F8|A0A7P0Z4F8_HUMAN,tr|A0A7P0TBP8|A0A7P0TBP8_HUMAN,tr|A0A7P0TB26|A0A7P0TB26_HUMAN,tr|A0A7P0T9U6|A0A7P0T9U6_HUMAN,tr|A0A7P0T9E3|A0A7P0T9E3_HUMAN,tr|A0A7P0TBA3|A0A7P0TBA3_HUMAN,tr|I3L0S0|I3L0S0_HUMAN,tr|I3L3P5|I3L3P5_HUMAN,tr|A0A7P0T940|A0A7P0T940_HUMAN,tr|A0A7P0T8J3|A0A7P0T8J3_HUMAN,tr|A0A7P0Z4J0|A0A7P0Z4J0_HUMAN,tr|A0A7P0T9S9|A0A7P0T9S9_HUMAN,tr|A0A7P0T8X1|A0A7P0T8X1_HUMAN,tr|I3L3U6|I3L3U6_HUMAN" 31 1165.5971 1.55 47200 13019 2 1165.594539 583.8058 Protein disulfide-isomerase OS=Homo sapiens OX=9606 GN=P4HB PE=1 SV=3 6.47 2501.3 - 555911 - - - -2.216 - 2.088 0.524 - 375.3 1 2 0 -0.0026 11 0 0 0 1.85E+07 1.19E+07 - - - 4.9021 0.8986 221125_WJC_METTL3_EV_vs_WT_F04.13025.13025.3 0.0114 Dec-44 K.LK[136.11]QSLPPGLAVK[136.11].E sp|P63173|RL38_HUMAN 1 1265.8042 1.02 47204 13025 3 1265.80124 422.942 60S ribosomal protein L38 OS=Homo sapiens OX=9606 GN=RPL38 PE=1 SV=2 10 2502 - 1.19E+06 - - - -2.3448 - 1.854 0.137 - 164.7 1 2 1 -0.003 12 0 0 0 6.47E+07 6.32E+07 - - - 1.7778 0.9964 221125_WJC_METTL3_EV_vs_WT_F04.13027.13027.2 1.67 16-Sep K.LQISTNLQR[166.11].R "sp|Q92878|RAD50_HUMAN,tr|A0A494C1B7|A0A494C1B7_HUMAN,tr|A0A1W2PQ90|A0A1W2PQ90_HUMAN" 3 1081.6119 0.59 47206 13027 2 1081.610724 541.8132 DNA repair protein RAD50 OS=Homo sapiens OX=9606 GN=RAD50 PE=1 SV=1 9.75 2502.2 - 762858 - - - -1.1122 - 1.913 0.081 - 231.5 1 2 0 -0.0012 9 0 0 0 7.61E+06 1.29E+07 - - - 1.5155 0.998 221125_WJC_METTL3_EV_vs_WT_F04.13032.13032.3 0.00264 Nov-44 K.ATVMDVK[136.11]PVDYR[166.11].E "sp|P27694|RFA1_HUMAN,tr|I3L4R8|I3L4R8_HUMAN" 2 1410.7296 1.03 47209 13032 3 1410.729785 471.2505 Replication protein A 70 kDa DNA-binding subunit OS=Homo sapiens OX=9606 GN=RPA1 PE=1 SV=2 6 2502.9 - 1.11E+06 - - - 0.1269 - 1.747 0.247 - 159.4 1 2 0 0.0002 12 0 0 0 1.64E+08 1.59E+08 - - - 2.8402 0.9994 221125_WJC_METTL3_EV_vs_WT_F04.13033.13033.2 0.000407 13/26 R.LSSSSATLLNSPDR.A "sp|Q14244|MAP7_HUMAN,tr|A0A087WZ40|A0A087WZ40_HUMAN" 2 1446.7314 1 47210 13033 2 1446.72657 724.373 Ensconsin OS=Homo sapiens OX=9606 GN=MAP7 PE=1 SV=1 5.84 2502.9 - 1.48E+06 - - - -3.3641 - 3.041 0.434 - 697.2 1 2 0 -0.0049 14 0 0 0 3.34E+07 3.35E+07 - - - 5.036 0.9996 221125_WJC_METTL3_EV_vs_WT_F04.13034.13034.3 0.0247 Sep-36 K.SVIDYQTHFR[166.11].L "sp|Q9Y3B3|TMED7_HUMAN,tr|A0A0A6YYA0|A0A0A6YYA0_HUMAN" 2 1274.6283 0.23 47211 13034 3 1274.627357 425.8834 Transmembrane emp24 domain-containing protein 7 OS=Homo sapiens OX=9606 GN=TMED7 PE=1 SV=2 6.46 2503 - 624472 - - - -0.7445 - 1.623 0.364 - 85.6 1 2 0 -0.0009 10 0 0 0 2.54E+07 1.11E+08 - - - 4.0123 0.9979 221125_WJC_METTL3_EV_vs_WT_F04.13038.13038.2 0.00127 14-Sep K.KGADVWFK.E sp|P05109|S10A8_HUMAN 1 949.5022 88.03 47213 13038 2 949.500581 475.7584 Protein S100-A8 OS=Homo sapiens OX=9606 GN=S100A8 PE=1 SV=1 8.59 2503.6 - 1.08E+06 - - - -1.6546 - 1.827 0.183 - 229.5 1 2 0 -0.0016 8 0 0 0 5.40E+07 6.13E+05 - - - 2.2098 0.9642 221125_WJC_METTL3_EV_vs_WT_F04.13039.13039.3 0.00129 15/48 L.NVIEGPVFRPGSK.T sp|Q02413|DSG1_HUMAN 1 1398.7619 62.08 47214 13039 3 1398.757866 467.2613 Desmoglein-1 OS=Homo sapiens OX=9606 GN=DSG1 PE=1 SV=2 8.75 2503.7 - 703890 - - - -2.919 - 2.52 0.372 - 282.8 1 1 0 -0.0041 13 0 0 0 4.52E+07 7.27E+05 - - - 5.1922 0.9971 221125_WJC_METTL3_EV_vs_WT_F04.13040.13040.3 0.622 Oct-36 K.SVIDYQTHFR.L "sp|Q9Y3B3|TMED7_HUMAN,tr|A0A0A6YYA0|A0A0A6YYA0_HUMAN" 2 1264.62 0.23 47215 13040 3 1264.621332 422.5473 Transmembrane emp24 domain-containing protein 7 OS=Homo sapiens OX=9606 GN=TMED7 PE=1 SV=2 6.46 2503.7 - 1.20E+06 - - - 1.0248 - 1.744 0.224 - 110.1 1 2 0 0.0013 10 0 0 0 2.20E+07 9.50E+07 - - - 2.6613 0.9999 221125_WJC_METTL3_EV_vs_WT_F04.13041.13041.2 0.000382 20-Dec K.NSLDC[160.03]EIVSAK[136.11].S sp|Q01518|CAP1_HUMAN 1 1242.6006 2.5 47216 13041 2 1242.599704 622.3076 Adenylyl cyclase-associated protein 1 OS=Homo sapiens OX=9606 GN=CAP1 PE=1 SV=5 4.37 2503.9 - 520761 - - - -0.6832 - 2.46 0.533 - 644.4 1 2 0 -0.0008 11 0 0 0 2.39E+07 9.56E+06 - - - 5.4126 1 221125_WJC_METTL3_EV_vs_WT_F04.13049.13049.2 4.43E-08 22-Nov K.YSQVLANGLDNK[136.11].L "sp|P62269|RS18_HUMAN,tr|J3JS69|J3JS69_HUMAN" 2 1328.6816 1.01 47222 13049 2 1328.679683 665.3481 40S ribosomal protein S18 OS=Homo sapiens OX=9606 GN=RPS18 PE=1 SV=3 5.83 2504.9 - 1.42E+07 - - - -1.4277 - 2.492 0.654 - 364.3 1 2 0 -0.0019 12 0 0 0 8.74E+08 8.68E+08 - - - 6.2733 1 221125_WJC_METTL3_EV_vs_WT_F04.13050.13050.2 2.88E-08 13/22 K.YSQVLANGLDNK.L "sp|P62269|RS18_HUMAN,tr|J3JS69|J3JS69_HUMAN" 2 1320.6674 1.01 47223 13050 2 1320.665581 661.341 40S ribosomal protein S18 OS=Homo sapiens OX=9606 GN=RPS18 PE=1 SV=3 5.83 2504.9 - 1.28E+07 - - - -1.3622 - 2.729 0.632 - 556.2 1 2 0 -0.0018 12 0 0 0 8.74E+08 8.68E+08 - - - 6.3499 0.9998 221125_WJC_METTL3_EV_vs_WT_F04.13053.13053.3 0.0161 15/44 K.ATVMDVKPVDYR.E "sp|P27694|RFA1_HUMAN,tr|I3L4R8|I3L4R8_HUMAN" 2 1392.7071 1.05 47226 13053 3 1392.706005 465.243 Replication protein A 70 kDa DNA-binding subunit OS=Homo sapiens OX=9606 GN=RPA1 PE=1 SV=2 6 2505.1 - 2.03E+06 - - - -0.8121 - 2.019 0.353 - 285.2 1 2 0 -0.0011 12 0 0 0 1.63E+08 1.55E+08 - - - 4.4228 0.9988 221125_WJC_METTL3_EV_vs_WT_F04.13055.13055.2 0.0568 18-Oct R.IDISPSTFRK.H "sp|Q9Y2W1|TR150_HUMAN,tr|A0A3B3ITZ9|A0A3B3ITZ9_HUMAN" 2 1162.6346 4.28 47228 13055 2 1162.633254 582.3246 Thyroid hormone receptor-associated protein 3 OS=Homo sapiens OX=9606 GN=THRAP3 PE=1 SV=2 8.75 2505.4 - 808881 - - - -1.1775 - 2.075 0.186 - 262.6 1 2 0 -0.0014 10 0 0 0 1.88E+07 4.39E+06 - - - 2.4519 0.9913 221125_WJC_METTL3_EV_vs_WT_F04.13056.13056.2 3.01E-07 20-Nov R.QAHLC[160.03]VLASNC[160.03].D sp|P25398|RS12_HUMAN 1 1271.5751 - 47229 13056 2 1271.573092 636.7948 40S ribosomal protein S12 OS=Homo sapiens OX=9606 GN=RPS12 PE=1 SV=3 6.72 2505.5 - 791524 - - - -1.5611 - 2.336 0.558 - 433.4 1 1 0 -0.002 11 0 0 0 - - - - - 5.457 0.996 221125_WJC_METTL3_EV_vs_WT_F04.13059.13059.3 0.007 Dec-40 R.TREPLILEEER.E sp|Q9UNX4|WDR3_HUMAN 1 1383.7358 1.53 47232 13059 3 1383.735464 462.2525 WD repeat-containing protein 3 OS=Homo sapiens OX=9606 GN=WDR3 PE=1 SV=1 4.49 2505.9 - 601488 - - - -0.2385 - 2.038 0.256 - 147.2 1 2 1 -0.0003 11 0 0 0 5.12E+06 3.34E+06 - - - 3.4166 0.9976 221125_WJC_METTL3_EV_vs_WT_F04.13061.13061.3 0.0386 Dec-40 K.KLVESLPQEIK.A "sp|P52815|RM12_HUMAN,tr|B4DLN1|B4DLN1_HUMAN" 2 1282.7497 1.97 47234 13061 3 1282.746731 428.5905 "39S ribosomal protein L12, mitochondrial OS=Homo sapiens OX=9606 GN=MRPL12 PE=1 SV=2" 6.14 2506.2 - 383392 - - - -2.2779 - 1.938 0.254 - 277.9 1 2 0 -0.0029 11 0 0 0 4.42E+08 2.24E+08 - - - 3.2507 0.9842 221125_WJC_METTL3_EV_vs_WT_F04.13062.13062.2 0.228 16-Jun K.ESQPAIWNR.D sp|Q14676|MDC1_HUMAN 1 1099.5411 1.37 47235 13062 2 1099.541701 550.7778 Mediator of DNA damage checkpoint protein 1 OS=Homo sapiens OX=9606 GN=MDC1 PE=1 SV=3 6.1 2506.3 - 339216 - - - 0.5857 - 0.965 0.196 - 109.9 1 2 0 0.0006 9 0 0 0 5.42E+06 3.96E+06 - - - 0.3854 1 221125_WJC_METTL3_EV_vs_WT_F04.13065.13065.3 0.000754 13/44 R.HVFLTGPPGVGK[136.11].T "sp|Q9BSD7|NTPCR_HUMAN,tr|Q5TDF0|Q5TDF0_HUMAN" 2 1215.6855 1.18 47237 13065 3 1215.683738 406.2358 Cancer-related nucleoside-triphosphatase OS=Homo sapiens OX=9606 GN=NTPCR PE=1 SV=1 8.76 2506.7 - 4.38E+06 - - - -1.4848 - 2.503 0.496 - 353.6 1 2 0 -0.0018 12 0 0 0 7.16E+08 6.06E+08 - - - 6.6126 0.9929 221125_WJC_METTL3_EV_vs_WT_F04.13067.13067.2 5.44E-06 13/28 A.GGGGGFGAAGGFGGR.G sp|P35908|K22E_HUMAN 1 1180.5374 999 47238 13067 2 1180.536079 591.276 "Keratin, type II cytoskeletal 2 epidermal OS=Homo sapiens OX=9606 GN=KRT2 PE=1 SV=2" 9.75 2506.9 - 1.02E+07 - - - -1.0927 - 2.49 0.547 - 487.8 1 1 0 -0.0013 15 0 0 0 2.32E+08 0.00E+00 - - - 5.3236 1 221125_WJC_METTL3_EV_vs_WT_F04.13069.13069.2 8.81E-06 20-Dec R.VVIFQQEQENK[136.11].L "sp|P63151|2ABA_HUMAN,tr|E5RIY1|E5RIY1_HUMAN" 2 1368.7129 0.52 47240 13069 2 1368.710641 685.3637 Serine\threonine-protein phosphatase 2A 55 kDa regulatory subunit B alpha isoform OS=Homo sapiens OX=9606 GN=PPP2R2A PE=1 SV=1 4.53 2507 - 2.68E+06 - - - -1.6358 - 2.486 0.595 - 487.1 1 2 0 -0.0022 11 0 0 0 4.88E+07 9.35E+07 - - - 5.8986 0.9986 221125_WJC_METTL3_EV_vs_WT_F04.13070.13070.3 1.59E-06 20/68 R.PAAAVAQPLEPGPGPPER.A sp|Q14681|KCTD2_HUMAN 1 1752.9159 6.32 47241 13070 3 1752.915165 585.3126 BTB\POZ domain-containing protein KCTD2 OS=Homo sapiens OX=9606 GN=KCTD2 PE=1 SV=3 4.53 2507.1 - 2.43E+06 - - - -0.4096 - 3.743 0.533 - 445.1 1 1 0 -0.0007 18 0 0 0 1.90E+08 3.00E+07 - - - 7.7689 0.9997 221125_WJC_METTL3_EV_vs_WT_F04.13071.13071.2 0.00205 14-Dec R.HLDLASLK.S "sp|Q8NBN7|RDH13_HUMAN,tr|K7EMY5|K7EMY5_HUMAN,tr|G8JLA1|G8JLA1_HUMAN" 3 895.5127 0.72 47242 13071 2 895.511127 448.7636 Retinol dehydrogenase 13 OS=Homo sapiens OX=9606 GN=RDH13 PE=1 SV=2 6.74 2507.2 - 1.49E+06 - - - -1.7755 - 2.353 0.365 - 259.5 1 2 0 -0.0016 8 0 0 0 1.45E+07 2.01E+07 - - - 4.3171 0.9918 221125_WJC_METTL3_EV_vs_WT_F04.13072.13072.3 7.25E-07 22/52 S.AVPELATDPELEK[136.11]K[136.11].L "sp|Q86U44|MTA70_HUMAN,tr|B4E349|B4E349_HUMAN,tr|F5H6D8|F5H6D8_HUMAN,tr|H0YFV6|H0YFV6_HUMAN,tr|B4DTN4|B4DTN4_HUMAN" 5 1554.8476 0 47243 13072 3 1554.842006 519.2898 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 4.41 2507.3 - 1.36E+06 - - - -3.5907 - 3.376 0.529 - 678.7 1 1 0 -0.0056 14 0 0 0 5.53E+05 5.48E+08 - - - 7.6697 0.9999 221125_WJC_METTL3_EV_vs_WT_F04.13073.13073.2 2.38E-06 22-Dec K.SC[160.03]ALAEDPQELR.D "sp|Q8IX12|CCAR1_HUMAN,tr|F5H2E6|F5H2E6_HUMAN,tr|F5H1H2|F5H1H2_HUMAN,tr|A0A0C4DGG8|A0A0C4DGG8_HUMAN,tr|F5H3E1|F5H3E1_HUMAN" 5 1387.6402 4.6 47244 13073 2 1387.637863 694.8274 Cell division cycle and apoptosis regulator protein 1 OS=Homo sapiens OX=9606 GN=CCAR1 PE=1 SV=2 4.14 2507.4 - 1.28E+06 - - - -1.669 - 2.54 0.567 - 502.7 1 2 0 -0.0023 12 0 0 0 8.28E+07 1.80E+07 - - - 5.6808 1 221125_WJC_METTL3_EV_vs_WT_F04.13075.13075.2 1.17E-09 14/34 R.PAAAVAQPLEPGPGPPER.A sp|Q14681|KCTD2_HUMAN 1 1752.9159 4.94 47246 13075 2 1752.9136 877.4652 BTB\POZ domain-containing protein KCTD2 OS=Homo sapiens OX=9606 GN=KCTD2 PE=1 SV=3 4.53 2507.7 - 568743 - - - -1.3024 - 3.181 0.694 - 514.9 1 1 0 -0.0023 18 0 0 0 6.55E+07 1.33E+07 - - - 7.0112 0.999 221125_WJC_METTL3_EV_vs_WT_F04.13078.13078.3 0.000767 Oct-44 R.SPSDLHISPLAK.K "sp|O95785|WIZ_HUMAN,tr|A0A669KBG4|A0A669KBG4_HUMAN,tr|A0A2R8YFV2|A0A2R8YFV2_HUMAN,tr|A0A669KAV7|A0A669KAV7_HUMAN,tr|M0QXA7|M0QXA7_HUMAN,tr|A0A669KBH9|A0A669KBH9_HUMAN,tr|B9EGQ5|B9EGQ5_HUMAN" 7 1263.6823 1.26 47247 13078 3 1263.677125 422.2347 Protein Wiz OS=Homo sapiens OX=9606 GN=WIZ PE=1 SV=2 6.46 2508.1 - 3.61E+06 - - - -4.0968 - 2.22 0.381 - 106.5 1 2 0 -0.0052 12 0 0 0 4.21E+07 3.33E+07 - - - 4.9969 1 221125_WJC_METTL3_EV_vs_WT_F04.13080.13080.3 2.59E-06 14/44 R.SPSDLHISPLAK[136.11].K "sp|O95785|WIZ_HUMAN,tr|A0A669KBG4|A0A669KBG4_HUMAN,tr|A0A2R8YFV2|A0A2R8YFV2_HUMAN,tr|A0A669KAV7|A0A669KAV7_HUMAN,tr|M0QXA7|M0QXA7_HUMAN,tr|A0A669KBH9|A0A669KBH9_HUMAN,tr|B9EGQ5|B9EGQ5_HUMAN" 7 1271.6965 1.26 47249 13080 3 1271.694639 424.9061 Protein Wiz OS=Homo sapiens OX=9606 GN=WIZ PE=1 SV=2 6.46 2508.2 - 2.71E+06 - - - -1.465 - 2.924 0.489 - 322.6 1 2 0 -0.0019 12 0 0 0 4.21E+07 3.33E+07 - - - 6.9654 0.9998 221125_WJC_METTL3_EV_vs_WT_F04.13081.13081.2 0.0404 14-Dec R.HLDLASLK[136.11].S "sp|Q8NBN7|RDH13_HUMAN,tr|K7EMY5|K7EMY5_HUMAN,tr|G8JLA1|G8JLA1_HUMAN" 3 903.5269 0.72 47250 13081 2 903.525234 452.7707 Retinol dehydrogenase 13 OS=Homo sapiens OX=9606 GN=RDH13 PE=1 SV=2 6.74 2508.3 - 1.99E+06 - - - -1.8627 - 2.484 0.409 - 511.5 1 2 0 -0.0017 8 0 0 0 1.45E+07 2.01E+07 - - - 4.8055 0.9995 221125_WJC_METTL3_EV_vs_WT_F04.13083.13083.3 0.0823 Dec-40 K.K[136.11]LVESLPQEIK[136.11].A "sp|P52815|RM12_HUMAN,tr|B4DLN1|B4DLN1_HUMAN" 2 1298.7781 1.97 47252 13083 3 1298.776284 433.9333 "39S ribosomal protein L12, mitochondrial OS=Homo sapiens OX=9606 GN=MRPL12 PE=1 SV=2" 6.14 2508.4 - 1.55E+06 - - - -1.362 - 1.996 0.315 - 318 1 2 0 -0.0018 11 0 0 0 4.42E+08 2.24E+08 - - - 4.0149 1 221125_WJC_METTL3_EV_vs_WT_F04.13084.13084.2 0.000899 17/20 K.KLVESLPQEIK.A "sp|P52815|RM12_HUMAN,tr|B4DLN1|B4DLN1_HUMAN" 2 1282.7497 2.07 47253 13084 2 1282.749554 642.3821 "39S ribosomal protein L12, mitochondrial OS=Homo sapiens OX=9606 GN=MRPL12 PE=1 SV=2" 6.14 2508.6 - 1.27E+06 - - - -0.0772 - 2.972 0.51 - 985.2 1 2 0 -0.0001 11 0 0 0 1.95E+08 9.40E+07 - - - 5.7545 0.9997 221125_WJC_METTL3_EV_vs_WT_F04.13094.13094.3 0.000829 15/44 K.FAAQNLHQNLIR[166.11].K "sp|Q9H0C8|ILKAP_HUMAN,tr|E9PC05|E9PC05_HUMAN" 2 1433.7767 0.5 47261 13094 3 1433.77465 478.9328 Integrin-linked kinase-associated serine\threonine phosphatase 2C OS=Homo sapiens OX=9606 GN=ILKAP PE=1 SV=1 9.76 2509.7 - 1.01E+06 - - - -1.4305 - 2.859 0.272 - 211.7 1 2 0 -0.0021 12 0 0 0 5.56E+06 1.11E+07 - - - 4.4837 0.9999 221125_WJC_METTL3_EV_vs_WT_F04.13095.13095.2 9.71E-05 13/20 K.K[136.11]LVESLPQEIK[136.11].A "sp|P52815|RM12_HUMAN,tr|B4DLN1|B4DLN1_HUMAN" 2 1298.7781 2.07 47262 13095 2 1298.776506 650.3963 "39S ribosomal protein L12, mitochondrial OS=Homo sapiens OX=9606 GN=MRPL12 PE=1 SV=2" 6.14 2509.9 - 1.00E+06 - - - -1.1911 - 2.592 0.511 - 441.7 1 2 0 -0.0015 11 0 0 0 1.95E+08 9.40E+07 - - - 5.3913 0.9999 221125_WJC_METTL3_EV_vs_WT_F04.13096.13096.2 9.29E-08 13/22 K.DSAQNSVIIVDK.N "sp|P02786|TFR1_HUMAN,tr|G3V0E5|G3V0E5_HUMAN" 2 1287.667 2.31 47263 13096 2 1287.666625 644.8408 Transferrin receptor protein 1 OS=Homo sapiens OX=9606 GN=TFRC PE=1 SV=2 4.21 2510 - 941196 - - - -0.3262 - 2.616 0.548 - 883.8 1 2 0 -0.0004 12 0 0 0 1.97E+07 8.54E+06 - - - 5.6187 0.9997 221125_WJC_METTL3_EV_vs_WT_F04.13097.13097.2 0.0106 22-Nov R.GGSISVQVNSIK[136.11].F "sp|Q14978|NOLC1_HUMAN,tr|A0A0A0MRM9|A0A0A0MRM9_HUMAN" 2 1195.6652 1.83 47264 13097 2 1195.664048 598.8399 Nucleolar and coiled-body phosphoprotein 1 OS=Homo sapiens OX=9606 GN=NOLC1 PE=1 SV=2 8.75 2510.1 - 895201 - - - -0.9643 - 2.321 0.339 - 357.6 1 2 0 -0.0012 12 0 0 0 3.11E+07 1.70E+07 - - - 3.7599 0.9994 221125_WJC_METTL3_EV_vs_WT_F04.13098.13098.2 5.73E-06 13/24 R.TPTAPAVNLAGAR[166.11].T sp|Q9UQ35|SRRM2_HUMAN 1 1247.6862 0.9 47265 13098 2 1247.68234 624.8504 Serine\arginine repetitive matrix protein 2 OS=Homo sapiens OX=9606 GN=SRRM2 PE=1 SV=2 9.41 2510.3 - 797267 - - - -3.0577 - 2.364 0.481 - 461.9 1 2 0 -0.0038 13 0 0 0 1.37E+07 1.52E+07 - - - 4.8006 0.9857 221125_WJC_METTL3_EV_vs_WT_F04.13099.13099.2 0.993 18-Aug K.SSLGPVGLDK[136.11].M "sp|P17987|TCPA_HUMAN,tr|F5H726|F5H726_HUMAN,tr|F5H136|F5H136_HUMAN,tr|F5GZI8|F5GZI8_HUMAN,tr|E7ERF2|E7ERF2_HUMAN,tr|F5H676|F5H676_HUMAN,tr|F5GYL4|F5GYL4_HUMAN" 7 979.543 0.41 47266 13099 2 979.541136 490.7788 T-complex protein 1 subunit alpha OS=Homo sapiens OX=9606 GN=TCP1 PE=1 SV=1 5.55 2510.4 - 491477 - - - -1.8631 - 1.199 0.174 - 67.6 1 2 0 -0.0018 10 0 0 0 1.28E+07 3.14E+07 - - - 0.8322 1 221125_WJC_METTL3_EV_vs_WT_F04.13100.13100.2 6.48E-10 15/34 R.PAAAVAQPLEPGPGPPER[166.11].A sp|Q14681|KCTD2_HUMAN 1 1762.9242 4.92 47267 13100 2 1762.919323 882.4694 BTB\POZ domain-containing protein KCTD2 OS=Homo sapiens OX=9606 GN=KCTD2 PE=1 SV=3 4.53 2510.5 - 379234 - - - -2.7398 - 3.143 0.696 - 292 1 1 0 -0.0048 18 0 0 0 6.52E+07 1.33E+07 - - - 6.9956 0.9998 221125_WJC_METTL3_EV_vs_WT_F04.13103.13103.2 7.36E-05 26-Oct R.ELDEEGSDPPLPGR[166.11].A "sp|Q9BRJ6|CG050_HUMAN,tr|C9JQV0|C9JQV0_HUMAN,tr|H7C2R9|H7C2R9_HUMAN,tr|H7C0T1|H7C0T1_HUMAN" 4 1519.703 1.06 47270 13103 2 1519.701018 760.8588 Uncharacterized protein C7orf50 OS=Homo sapiens OX=9606 GN=C7orf50 PE=1 SV=1 3.83 2510.9 - 276145 - - - -1.2956 - 2.067 0.51 - 211 1 2 0 -0.002 14 0 0 0 1.17E+07 1.11E+07 - - - 4.6293 1 221125_WJC_METTL3_EV_vs_WT_F04.13108.13108.3 0.00557 Dec-44 K.YTFAAHMDGTYK.F "sp|Q15363|TMED2_HUMAN,tr|E7EQ72|E7EQ72_HUMAN" 2 1403.618 1.35 47273 13108 3 1403.616184 468.8799 Transmembrane emp24 domain-containing protein 2 OS=Homo sapiens OX=9606 GN=TMED2 PE=1 SV=1 6.74 2511.5 - 1.63E+06 - - - -1.2845 - 2.671 0.523 - 123.9 1 2 0 -0.0018 12 0 0 0 3.96E+07 2.94E+07 - - - 7.0936 0.9995 221125_WJC_METTL3_EV_vs_WT_F04.13110.13110.2 0.00014 24-Oct K.IGDLTGYC[160.03]TNPNR.H "sp|Q9NVN8|GNL3L_HUMAN,tr|A0A6I8PL80|A0A6I8PL80_HUMAN,tr|A0A6I8PS19|A0A6I8PS19_HUMAN" 3 1479.6776 2.04 47275 13110 2 1479.673197 740.8461 Guanine nucleotide-binding protein-like 3-like protein OS=Homo sapiens OX=9606 GN=GNL3L PE=1 SV=1 5.83 2511.7 - 754092 - - - -2.9939 - 2.122 0.529 - 163.1 1 2 0 -0.0044 13 0 0 0 6.11E+06 2.99E+06 - - - 4.8778 0.9987 221125_WJC_METTL3_EV_vs_WT_F04.13114.13114.2 0.0105 18-Sep K.SESGYGFNVR[166.11].G "sp|Q96L92|SNX27_HUMAN,tr|A0A2R8YD75|A0A2R8YD75_HUMAN,tr|A0A2R8Y8A7|A0A2R8Y8A7_HUMAN,tr|A0A2R8Y871|A0A2R8Y871_HUMAN,tr|H7C603|H7C603_HUMAN" 5 1124.5126 1.19 47279 13114 2 1124.513131 563.2636 Sorting nexin-27 OS=Homo sapiens OX=9606 GN=SNX27 PE=1 SV=2 5.72 2512.3 - 606421 - - - 0.466 - 1.604 0.246 - 323.7 1 2 0 0.0005 10 0 0 0 8.53E+06 7.16E+06 - - - 2.1767 0.9825 221125_WJC_METTL3_EV_vs_WT_F04.13119.13119.2 0.0203 18-Oct L.NVELDPEIQK.V "sp|Q86Y46|K2C73_HUMAN,sp|Q7RTS7|K2C74_HUMAN,sp|Q3SY84|K2C71_HUMAN,sp|P04264|K2C1_HUMAN,tr|F8W1S1|F8W1S1_HUMAN" 5 1183.6085 1481.78 47282 13119 2 1183.607534 592.8115 "Keratin, type II cytoskeletal 73 OS=Homo sapiens OX=9606 GN=KRT73 PE=1 SV=1" 4.14 2512.9 - 1.96E+07 - - - -0.7891 - 1.896 0.39 - 283.4 1 1 0 -0.0009 10 0 0 0 1.06E+09 7.16E+05 - - - 3.707 1 221125_WJC_METTL3_EV_vs_WT_F04.13120.13120.2 2.97E-06 16/22 V.PELATDPELEK[136.11]K[136.11].L "sp|Q86U44|MTA70_HUMAN,tr|B4E349|B4E349_HUMAN,tr|F5H6D8|F5H6D8_HUMAN,tr|H0YFV6|H0YFV6_HUMAN,tr|B4DTN4|B4DTN4_HUMAN" 5 1384.7421 2.3 47283 13120 2 1384.740952 693.3783 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 4.41 2513 - 2.33E+06 - - - -0.8009 - 3.213 0.553 - 808.7 1 1 0 -0.0011 12 0 0 0 9.15E+07 3.98E+07 - - - 6.1962 0.9983 221125_WJC_METTL3_EV_vs_WT_F04.13122.13122.3 0.00955 Sep-32 R.VYSLDDIR[166.11]R[166.11].Y sp|Q14566|MCM6_HUMAN 1 1155.6151 0.48 47285 13122 3 1155.613243 386.2123 DNA replication licensing factor MCM6 OS=Homo sapiens OX=9606 GN=MCM6 PE=1 SV=1 5.93 2513.2 - 685381 - - - -1.6173 - 1.634 0.283 - 134.5 1 2 0 -0.0019 9 0 0 0 5.09E+06 1.06E+07 - - - 3.1745 0.977 221125_WJC_METTL3_EV_vs_WT_F04.13124.13124.3 0.00459 Nov-36 R.GYLDKLEPSK.L sp|P25705|ATPA_HUMAN 1 1148.6077 0.55 47287 13124 3 1148.604706 383.8765 "ATP synthase subunit alpha, mitochondrial OS=Homo sapiens OX=9606 GN=ATP5F1A PE=1 SV=1" 6.07 2513.5 - 561852 - - - -2.6415 - 1.921 0.221 - 135.1 1 2 1 -0.003 10 0 0 0 2.01E+07 3.62E+07 - - - 2.9097 0.9995 221125_WJC_METTL3_EV_vs_WT_F04.13126.13126.2 0.00106 26-Sep R.ELDEEGSDPPLPGR.A "sp|Q9BRJ6|CG050_HUMAN,tr|C9JQV0|C9JQV0_HUMAN,tr|H7C2R9|H7C2R9_HUMAN,tr|H7C0T1|H7C0T1_HUMAN" 4 1509.6947 1.05 47289 13126 2 1509.692004 755.8546 Uncharacterized protein C7orf50 OS=Homo sapiens OX=9606 GN=C7orf50 PE=1 SV=1 3.83 2513.8 - 466269 - - - -1.7971 - 1.987 0.391 - 159.4 1 2 0 -0.0027 14 0 0 0 1.12E+07 1.07E+07 - - - 3.6511 0.9983 221125_WJC_METTL3_EV_vs_WT_F04.13127.13127.2 0.000181 20-Nov R.VSFC[160.03]APGPPGR[166.11].S "sp|Q8IY67|RAVR1_HUMAN,tr|E9PAU2|E9PAU2_HUMAN,tr|A0A087WZ13|A0A087WZ13_HUMAN" 3 1153.5578 0.89 47290 13127 2 1153.552838 577.7862 Ribonucleoprotein PTB-binding 1 OS=Homo sapiens OX=9606 GN=RAVER1 PE=1 SV=1 8.22 2513.9 - 448550 - - - -4.2867 - 1.977 0.492 - 385.8 1 2 0 -0.0049 11 0 0 0 1.46E+08 1.63E+08 - - - 4.5172 0.9796 221125_WJC_METTL3_EV_vs_WT_F04.13128.13128.2 0.199 18-Jul R.STIIGESISR.L sp|P54136|SYRC_HUMAN 1 1061.5717 0.5 47291 13128 2 1061.568675 531.7931 "Arginine--tRNA ligase, cytoplasmic OS=Homo sapiens OX=9606 GN=RARS1 PE=1 SV=2" 5.72 2514 - 411295 - - - -2.8382 - 1.239 0.194 - 112.2 1 2 0 -0.003 10 0 0 0 3.49E+06 6.97E+06 - - - 1.0711 0.9925 221125_WJC_METTL3_EV_vs_WT_F04.13131.13131.2 7.44E-07 13/26 S.AVPELATDPELEK[136.11]K[136.11].L "sp|Q86U44|MTA70_HUMAN,tr|B4E349|B4E349_HUMAN,tr|F5H6D8|F5H6D8_HUMAN,tr|H0YFV6|H0YFV6_HUMAN,tr|B4DTN4|B4DTN4_HUMAN" 5 1554.8476 0.001 47292 13131 2 1554.845922 778.4311 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 4.41 2514.4 - 2.16E+06 - - - -1.0721 - 2.358 0.542 - 366.6 1 1 0 -0.0017 14 0 0 0 0.00E+00 3.15E+07 - - - 5.1963 0.9796 221125_WJC_METTL3_EV_vs_WT_F04.13132.13132.3 0.0374 Dec-52 S.AVPELATDPELEK[136.11]K.L "sp|Q86U44|MTA70_HUMAN,tr|B4E349|B4E349_HUMAN,tr|F5H6D8|F5H6D8_HUMAN,tr|H0YFV6|H0YFV6_HUMAN,tr|B4DTN4|B4DTN4_HUMAN" 5 1546.8334 - 47293 13132 3 1546.832668 516.6184 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 4.41 2514.5 - 1.57E+06 - - - -0.4661 - 2.436 0.329 - 175.7 1 1 0 -0.0007 14 0 0 0 - - - - - 4.574 0.9999 221125_WJC_METTL3_EV_vs_WT_F04.13135.13135.3 7.35E-06 13/40 R.TGAHLELSLAK.D "sp|Q00341|VIGLN_HUMAN,tr|C9JHZ8|C9JHZ8_HUMAN,tr|C9JZI8|C9JZI8_HUMAN,tr|A0A024R4E5|A0A024R4E5_HUMAN,tr|C9JIZ1|C9JIZ1_HUMAN,tr|H7C0A4|H7C0A4_HUMAN,tr|C9JES8|C9JES8_HUMAN,tr|C9J5E5|C9J5E5_HUMAN,tr|C9JHS7|C9JHS7_HUMAN" 9 1138.6346 0.9 47296 13135 3 1138.633891 380.5522 Vigilin OS=Homo sapiens OX=9606 GN=HDLBP PE=1 SV=2 6.41 2514.7 - 604257 - - - -0.6429 - 2.125 0.436 - 195.1 1 2 0 -0.0007 11 0 0 0 7.50E+06 8.32E+06 - - - 5.5421 1 221125_WJC_METTL3_EV_vs_WT_F04.13137.13137.2 3.51E-07 26-Dec K.QLSVEPYSQEEAER.A sp|O00488|ZN593_HUMAN 1 1663.7689 1.7 47298 13137 2 1663.766042 832.8917 Zinc finger protein 593 OS=Homo sapiens OX=9606 GN=ZNF593 PE=1 SV=2 4.09 2515 - 282308 - - - -1.7442 - 2.446 0.634 - 299 1 2 0 -0.0029 14 0 0 0 1.98E+07 1.17E+07 - - - 5.9674 0.9998 221125_WJC_METTL3_EV_vs_WT_F04.13140.13140.2 0.00904 16-Oct K.SWNETLTSR.L "sp|O75947|ATP5H_HUMAN,tr|F5H608|F5H608_HUMAN" 2 1092.52 1.33 47300 13140 2 1092.518517 547.2673 "ATP synthase subunit d, mitochondrial OS=Homo sapiens OX=9606 GN=ATP5PD PE=1 SV=3" 5.72 2515.4 - 9.54E+06 - - - -1.3455 - 1.945 0.52 - 453.3 1 2 0 -0.0015 9 0 0 0 1.19E+08 8.97E+07 - - - 4.8059 0.9998 221125_WJC_METTL3_EV_vs_WT_F04.13142.13142.2 0.000105 16-Aug K.SWNETLTSR[166.11].L "sp|O75947|ATP5H_HUMAN,tr|F5H608|F5H608_HUMAN" 2 1102.5283 1.33 47301 13142 2 1102.52686 552.2714 "ATP synthase subunit d, mitochondrial OS=Homo sapiens OX=9606 GN=ATP5PD PE=1 SV=3" 5.72 2515.6 - 8.02E+06 - - - -1.2671 - 1.716 0.499 - 295.1 1 2 0 -0.0014 9 0 0 0 1.19E+08 8.97E+07 - - - 4.2884 0.9999 221125_WJC_METTL3_EV_vs_WT_F04.13145.13145.3 8.50E-06 14/48 K.FLEEHPGGEEVLR.E sp|P00167|CYB5_HUMAN 1 1510.7416 1.82 47304 13145 3 1510.73919 504.5878 Cytochrome b5 OS=Homo sapiens OX=9606 GN=CYB5A PE=1 SV=2 4.48 2515.9 - 794419 - - - -1.5999 - 2.314 0.467 - 167.5 1 2 0 -0.0024 13 0 0 0 9.88E+06 5.44E+06 - - - 6.0206 0.9999 221125_WJC_METTL3_EV_vs_WT_F04.13146.13146.3 7.23E-07 13/40 R.TGAHLELSLAK[136.11].D "sp|Q00341|VIGLN_HUMAN,tr|C9JHZ8|C9JHZ8_HUMAN,tr|C9JZI8|C9JZI8_HUMAN,tr|A0A024R4E5|A0A024R4E5_HUMAN,tr|C9JIZ1|C9JIZ1_HUMAN,tr|H7C0A4|H7C0A4_HUMAN,tr|C9JES8|C9JES8_HUMAN,tr|C9J5E5|C9J5E5_HUMAN,tr|C9JHS7|C9JHS7_HUMAN" 9 1146.6488 0.9 47305 13146 3 1146.646345 383.2236 Vigilin OS=Homo sapiens OX=9606 GN=HDLBP PE=1 SV=2 6.41 2516 - 679191 - - - -2.1611 - 2.249 0.476 - 180.1 1 2 0 -0.0025 11 0 0 0 7.50E+06 8.32E+06 - - - 6.1487 0.9999 221125_WJC_METTL3_EV_vs_WT_F04.13147.13147.2 0.000125 14/24 K.ASQAEISSLQSVR.Q sp|Q08378|GOGA3_HUMAN 1 1374.7103 4.16 47306 13147 2 1374.709021 688.3624 Golgin subfamily A member 3 OS=Homo sapiens OX=9606 GN=GOLGA3 PE=1 SV=2 6.05 2516.1 - 579267 - - - -0.9355 - 2.681 0.482 - 740.9 1 2 0 -0.0013 13 0 0 0 7.46E+06 1.79E+06 - - - 5.1317 0.9356 221125_WJC_METTL3_EV_vs_WT_F04.13148.13148.2 0.0509 Nov-34 R.PAGGNGSGLC[160.03]GGGVLGAR[166.11].S sp|Q5JSZ5|PRC2B_HUMAN 1 1565.7608 1.97 47307 13148 2 1565.767181 783.8877 Protein PRRC2B OS=Homo sapiens OX=9606 GN=PRRC2B PE=1 SV=2 8.68 2516.2 - 356351 - - - 4.0798 - 2.846 0.456 - 336.8 1 1 0 0.0064 18 0 0 0 6.45E+06 3.27E+06 - - - 4.9784 0.9997 221125_WJC_METTL3_EV_vs_WT_F04.13150.13150.2 0.0191 22-Nov R.ETLPAEQDLTTK[136.11].N "sp|P25786|PSA1_HUMAN,tr|F5GX11|F5GX11_HUMAN" 2 1352.6915 2.18 47308 13150 2 1352.688533 677.353 Proteasome subunit alpha type-1 OS=Homo sapiens OX=9606 GN=PSMA1 PE=1 SV=1 4.14 2516.5 - 2.07E+06 - - - -2.1757 - 2.136 0.501 - 412.7 1 2 0 -0.0029 12 0 0 0 1.50E+08 6.88E+07 - - - 4.7373 1 221125_WJC_METTL3_EV_vs_WT_F04.13156.13156.2 2.80E-06 13/26 K.QLSVEPYSQEEAER[166.11].A sp|O00488|ZN593_HUMAN 1 1673.7772 1.7 47314 13156 2 1673.775264 837.8959 Zinc finger protein 593 OS=Homo sapiens OX=9606 GN=ZNF593 PE=1 SV=2 4.09 2517 - 852405 - - - -1.165 - 2.667 0.603 - 379.8 1 2 0 -0.002 14 0 0 0 1.98E+07 1.17E+07 - - - 5.9558 1 221125_WJC_METTL3_EV_vs_WT_F04.13157.13157.3 8.81E-10 14/44 R.TAAENEFVVLKK.D "sp|Q14CN4|K2C72_HUMAN,sp|P08729|K2C7_HUMAN,sp|Q5XKE5|K2C79_HUMAN" 3 1347.7398 28.69 47315 13157 3 1347.737565 450.2539 "Keratin, type II cytoskeletal 72 OS=Homo sapiens OX=9606 GN=KRT72 PE=1 SV=2" 5.81 2517.1 - 697381 - - - -1.6709 - 2.908 0.62 - 268.3 1 2 0 -0.0023 12 0 0 0 1.05E+07 3.66E+05 - - - 8.4106 0.9992 221125_WJC_METTL3_EV_vs_WT_F04.13158.13158.2 0.00028 14/24 R.TPTAPAVNLAGAR.T sp|Q9UQ35|SRRM2_HUMAN 1 1237.6779 0.9 47316 13158 2 1237.673471 619.8462 Serine\arginine repetitive matrix protein 2 OS=Homo sapiens OX=9606 GN=SRRM2 PE=1 SV=2 9.41 2517.3 - 676032 - - - -3.5664 - 2.479 0.48 - 552.8 1 2 0 -0.0044 13 0 0 0 1.39E+07 1.54E+07 - - - 4.9149 0.9968 221125_WJC_METTL3_EV_vs_WT_F04.13159.13159.2 1.27E-05 20-Dec K.QQMLENQMEVR.K sp|Q01082|SPTB2_HUMAN 1 1404.649 5.11 47317 13159 2 1404.6524 703.3318 "Spectrin beta chain, non-erythrocytic 1 OS=Homo sapiens OX=9606 GN=SPTBN1 PE=1 SV=2" 4.53 2517.4 - 672932 - - - 2.4426 - 2.342 0.136 - 705.3 1 2 0 0.0034 11 0 0 0 7.96E+06 1.56E+06 - - - 2.3466 0.9995 221125_WJC_METTL3_EV_vs_WT_F04.13162.13162.2 0.0841 14/16 R.KALADLIEK.E sp|O95628|CNOT4_HUMAN 1 999.5964 1.75 47318 13162 2 999.595119 500.8055 CCR4-NOT transcription complex subunit 4 OS=Homo sapiens OX=9606 GN=CNOT4 PE=1 SV=3 6.07 2517.8 - 1.40E+06 - - - -1.3285 - 2.717 0.209 - 677.6 1 2 0 -0.0013 9 0 0 0 2.11E+07 1.20E+07 - - - 3.4759 0.9964 221125_WJC_METTL3_EV_vs_WT_F04.13163.13163.3 1.37E-05 20/68 R.PAAAVAQPLEPGPGPPER[166.11].A sp|Q14681|KCTD2_HUMAN 1 1762.9242 6.38 47319 13163 3 1762.921117 588.6487 BTB\POZ domain-containing protein KCTD2 OS=Homo sapiens OX=9606 GN=KCTD2 PE=1 SV=3 4.53 2517.9 - 1.45E+06 - - - -1.7221 - 3.627 0.459 - 575.2 1 1 0 -0.003 18 0 0 0 1.92E+08 3.00E+07 - - - 6.8648 0.9927 221125_WJC_METTL3_EV_vs_WT_F04.13164.13164.3 3.45E-05 14/48 R.PR[166.11]PPTLLSQEQIK[136.11].Q sp|P55884|EIF3B_HUMAN 1 1523.879 1.24 47320 13164 3 1523.87798 508.967 Eukaryotic translation initiation factor 3 subunit B OS=Homo sapiens OX=9606 GN=EIF3B PE=1 SV=3 9.18 2518 - 867881 - - - -0.7008 - 2.583 0.398 - 261.2 1 1 0 -0.0011 13 0 0 0 1.60E+07 1.29E+07 - - - 5.5499 1 221125_WJC_METTL3_EV_vs_WT_F04.13167.13167.2 5.07E-05 17/30 A.TAAAAAAAAYSDGYGR.V "sp|O43251|RFOX2_HUMAN,tr|B0QYV1|B0QYV1_HUMAN,tr|A0A0G2JRD1|A0A0G2JRD1_HUMAN,tr|A0A0G2JRA5|A0A0G2JRA5_HUMAN,tr|S4R3K7|S4R3K7_HUMAN" 5 1485.6848 1.44 47323 13167 2 1485.682976 743.8497 RNA binding protein fox-1 homolog 2 OS=Homo sapiens OX=9606 GN=RBFOX2 PE=1 SV=3 5.5 2518.4 - 536591 - - - -1.2419 - 3.661 0.567 - 1118.3 1 1 0 -0.0018 16 0 0 0 7.16E+06 4.98E+06 - - - 6.4188 0.9917 221125_WJC_METTL3_EV_vs_WT_F04.13168.13168.3 1.52E-06 13/60 A.TAAAAAAAAYSDGYGR.V "sp|O43251|RFOX2_HUMAN,tr|B0QYV1|B0QYV1_HUMAN,tr|A0A0G2JRD1|A0A0G2JRD1_HUMAN,tr|A0A0G2JRA5|A0A0G2JRA5_HUMAN,tr|S4R3K7|S4R3K7_HUMAN" 5 1485.6848 1.3 47324 13168 3 1485.680557 496.2356 RNA binding protein fox-1 homolog 2 OS=Homo sapiens OX=9606 GN=RBFOX2 PE=1 SV=3 5.5 2518.5 - 493768 - - - -2.8701 - 2.417 0.541 - 163.4 1 1 0 -0.0043 16 0 0 0 4.32E+06 3.33E+06 - - - 6.8349 0.9992 221125_WJC_METTL3_EV_vs_WT_F04.13170.13170.3 0.0161 Nov-48 R.GLSTFPGAEHC[160.03]LR[166.11].A "sp|Q63ZY6|NSN5C_HUMAN,sp|Q3KNT7|NSN5B_HUMAN,sp|Q96P11|NSUN5_HUMAN" 3 1453.7012 0.96 47326 13170 3 1453.700309 485.5743 Putative methyltransferase NSUN5C OS=Homo sapiens OX=9606 GN=NSUN5P2 PE=5 SV=2 6.74 2518.8 - 247764 - - - -0.5806 - 1.725 0.309 - 169.3 1 2 0 -0.0008 13 0 0 0 3.53E+06 3.69E+06 - - - 3.4631 0.9923 221125_WJC_METTL3_EV_vs_WT_F04.13174.13174.2 3.28E-07 13/30 V.AGGGGGFGAAGGFGGR.G sp|P35908|K22E_HUMAN 1 1251.5745 16.22 47328 13174 2 1251.573371 626.7945 "Keratin, type II cytoskeletal 2 epidermal OS=Homo sapiens OX=9606 GN=KRT2 PE=1 SV=2" 9.79 2519.2 - 1.34E+06 - - - -0.8877 - 2.428 0.508 - 409.1 1 1 0 -0.0011 16 0 0 0 1.79E+07 1.10E+06 - - - 4.9736 0.9873 221125_WJC_METTL3_EV_vs_WT_F04.13175.13175.2 1.49E-07 18/28 K.LNSVAAAANGLGAEK[136.11].D sp|Q9H7S9|ZN703_HUMAN 1 1392.7452 2.75 47329 13175 2 1393.744761 697.3799 Zinc finger protein 703 OS=Homo sapiens OX=9606 GN=ZNF703 PE=1 SV=1 6 2519.3 - 1.59E+06 - - - 717.6603 - 3.317 0.538 - 1252.6 1 2 0 0.9995 15 0 0 0 8.49E+07 3.09E+07 - - - 5.6488 0.9998 221125_WJC_METTL3_EV_vs_WT_F04.13177.13177.3 1.56E-05 16/52 K.GSLSSLK[136.11]EEGGLYR[166.11].D "sp|Q9BUK6|MSTO1_HUMAN,tr|A0A3B3IUD2|A0A3B3IUD2_HUMAN" 2 1512.7903 4.23 47331 13177 3 1512.790657 505.2707 Protein misato homolog 1 OS=Homo sapiens OX=9606 GN=MSTO1 PE=1 SV=1 6.14 2519.5 - 1.03E+06 - - - 0.2413 - 2.59 0.473 - 274.4 1 2 1 0.0004 14 0 0 0 4.37E+07 1.03E+07 - - - 6.3424 0.9979 221125_WJC_METTL3_EV_vs_WT_F04.13180.13180.2 0.0357 18-Aug K.AGLVDDFEKK.F "sp|O75947|ATP5H_HUMAN,tr|F5H608|F5H608_HUMAN" 2 1120.5764 0.31 47334 13180 2 1120.580075 561.2955 "ATP synthase subunit d, mitochondrial OS=Homo sapiens OX=9606 GN=ATP5PD PE=1 SV=3" 4.56 2519.9 - 531062 - - - 3.2439 - 1.765 0.362 - 172.7 1 2 0 0.0036 10 0 0 0 9.96E+06 3.26E+07 - - - 3.2995 1 221125_WJC_METTL3_EV_vs_WT_F04.13181.13181.2 1.16E-05 14/22 R.HVFLTGPPGVGK[136.11].T "sp|Q9BSD7|NTPCR_HUMAN,tr|Q5TDF0|Q5TDF0_HUMAN" 2 1215.6855 2.66 47335 13181 2 1215.68499 608.85 Cancer-related nucleoside-triphosphatase OS=Homo sapiens OX=9606 GN=NTPCR PE=1 SV=1 8.76 2520 - 521697 - - - -0.4549 - 2.634 0.564 - 603.7 1 2 0 -0.0006 12 0 0 0 1.82E+09 6.83E+08 - - - 5.7548 0.9997 221125_WJC_METTL3_EV_vs_WT_F04.13182.13182.3 0.00255 Nov-36 K.DMLQAASHYR[166.11].Q sp|Q8WUM0|NU133_HUMAN 1 1200.5585 1.28 47336 13182 3 1200.556175 401.1934 Nuclear pore complex protein Nup133 OS=Homo sapiens OX=9606 GN=NUP133 PE=1 SV=2 6.74 2520.1 - 493641 - - - -1.9466 - 1.976 0.377 - 142.1 1 2 0 -0.0023 10 0 0 0 6.11E+06 4.78E+06 - - - 4.7316 0.9981 221125_WJC_METTL3_EV_vs_WT_F04.13184.13184.2 0.0113 22-Jul K.FNPPTGTDTMVK[136.11].A "sp|P52948|NUP98_HUMAN,tr|A0A3B3ITD8|A0A3B3ITD8_HUMAN" 2 1314.6369 38.13 47338 13184 2 1314.633831 658.3257 Nuclear pore complex protein Nup98-Nup96 OS=Homo sapiens OX=9606 GN=NUP98 PE=1 SV=4 5.84 2520.4 - 469407 - - - -2.3634 - 1.462 0.365 - 107.1 1 2 0 -0.0031 12 0 0 0 5.44E+08 1.43E+07 - - - 2.7352 0.9999 221125_WJC_METTL3_EV_vs_WT_F04.13189.13189.2 8.34E-05 16-Dec K.K[136.11]LVWVPSDK[136.11].S "sp|P35579|MYH9_HUMAN,tr|Q5BKV1|Q5BKV1_HUMAN,tr|B1AH99|B1AH99_HUMAN" 3 1086.6408 1.14 47341 13189 2 1086.640293 544.3277 Myosin-9 OS=Homo sapiens OX=9606 GN=MYH9 PE=1 SV=4 8.59 2521 - 1.39E+06 - - - -0.4951 - 2.502 0.47 - 603.8 1 2 0 -0.0005 9 0 0 0 3.20E+07 2.81E+07 - - - 5.1654 1 221125_WJC_METTL3_EV_vs_WT_F04.13198.13198.2 8.06E-09 26-Nov R.YTASGC[160.03]EVIAVNTR.S "sp|O60341|KDM1A_HUMAN,tr|R4GMQ1|R4GMQ1_HUMAN" 2 1539.7351 18.73 47350 13198 2 1539.733684 770.8748 Lysine-specific histone demethylase 1A OS=Homo sapiens OX=9606 GN=KDM1A PE=1 SV=2 5.99 2522.2 - 211459 - - - -0.9469 - 2.58 0.696 - 485.3 1 2 0 -0.0015 14 0 0 0 3.32E+06 1.77E+05 - - - 6.5596 0.9448 221125_WJC_METTL3_EV_vs_WT_F04.13200.13200.2 0.281 28-Apr K.SYLPPPEQPSSGSLK[136.11].V "sp|Q5T8P6|RBM26_HUMAN,tr|A0A087X0H9|A0A087X0H9_HUMAN" 2 1593.813 0.62 47352 13200 2 1593.814434 797.9138 RNA-binding protein 26 OS=Homo sapiens OX=9606 GN=RBM26 PE=1 SV=3 5.72 2522.4 - 99175 - - - 0.9073 - 0.975 0.148 - 18.6 9 2 0 0.0014 15 0 0 0 4.76E+05 7.70E+05 - - - -0.3548 0.9926 221125_WJC_METTL3_EV_vs_WT_F04.13202.13202.2 3.69E-05 20-Sep L.TVPAYFNDSQR[166.11].Q "sp|P38646|GRP75_HUMAN,sp|P54652|HSP72_HUMAN,sp|P0DMV8|HS71A_HUMAN,sp|P34931|HS71L_HUMAN,sp|P11142|HSP7C_HUMAN,sp|P0DMV9|HS71B_HUMAN,sp|P17066|HSP76_HUMAN,tr|E9PQQ4|E9PQQ4_HUMAN,tr|H0Y8K0|H0Y8K0_HUMAN,tr|E9PN89|E9PN89_HUMAN,tr|A0A7I2V2S7|A0A7I2V2S7_HUMAN,tr|A0A7I2V2G2|A0A7I2V2G2_HUMAN,tr|E9PLF4|E9PLF4_HUMAN,tr|Q53FA3|Q53FA3_HUMAN,tr|E9PI65|E9PI65_HUMAN,tr|E9PK54|E9PK54_HUMAN,tr|A0A7I2V3F7|A0A7I2V3F7_HUMAN,tr|A0A7I2YQB2|A0A7I2YQB2_HUMAN,tr|E9PQK7|E9PQK7_HUMAN,tr|A0A0G2JIW1|A0A0G2JIW1_HUMAN,tr|D6RCD7|D6RCD7_HUMAN" 21 1306.6181 0.06 47353 13202 2 1306.619002 654.3163 "Stress-70 protein, mitochondrial OS=Homo sapiens OX=9606 GN=HSPA9 PE=1 SV=2" 5.5 2522.6 - 4.19E+06 - - - 0.6635 - 1.783 0.606 - 338.3 1 1 0 0.0009 11 0 0 0 4.22E+06 7.26E+07 - - - 5.0811 0.9999 221125_WJC_METTL3_EV_vs_WT_F04.13204.13204.2 0.000221 13/16 K.KLVWVPSDK.S "sp|P35579|MYH9_HUMAN,tr|Q5BKV1|Q5BKV1_HUMAN,tr|B1AH99|B1AH99_HUMAN" 3 1070.6124 1.15 47354 13204 2 1070.612582 536.3135 Myosin-9 OS=Homo sapiens OX=9606 GN=MYH9 PE=1 SV=4 8.59 2522.9 - 2.23E+06 - - - 0.141 - 2.65 0.426 - 766.5 1 2 0 0.0002 9 0 0 0 3.22E+07 2.81E+07 - - - 5.0068 0.9967 221125_WJC_METTL3_EV_vs_WT_F04.13205.13205.3 0.000534 15/36 K.AGLVDDFEK[136.11]K[136.11].F "sp|O75947|ATP5H_HUMAN,tr|F5H608|F5H608_HUMAN" 2 1136.6048 0.001 47355 13205 3 1137.60574 379.8756 "ATP synthase subunit d, mitochondrial OS=Homo sapiens OX=9606 GN=ATP5PD PE=1 SV=3" 4.56 2522.9 - 1.66E+06 - - - 880.6051 - 2.574 0.426 - 301.1 1 2 0 1.0009 10 0 0 0 0.00E+00 1.23E+06 - - - 5.7734 0.9999 221125_WJC_METTL3_EV_vs_WT_F04.13206.13206.3 0.000128 Nov-44 K.VLKPIQLTDPGK.L "sp|Q9Y2P8|RCL1_HUMAN,tr|Q5VZU3|Q5VZU3_HUMAN" 2 1307.7813 1.01 47356 13206 3 1307.781141 436.9344 RNA 3'-terminal phosphate cyclase-like protein OS=Homo sapiens OX=9606 GN=RCL1 PE=1 SV=3 8.56 2523.1 - 902276 - - - -0.1116 - 2.221 0.434 - 143.2 1 2 0 -0.0001 12 0 0 0 1.41E+07 1.39E+07 - - - 5.5904 0.9828 221125_WJC_METTL3_EV_vs_WT_F04.13208.13208.2 0.000892 16-Nov K.SHLFFTAGK[136.11].D sp|Q9UNX4|WDR3_HUMAN 1 1014.5378 2.87 47358 13208 2 1014.542782 508.2762 WD repeat-containing protein 3 OS=Homo sapiens OX=9606 GN=WDR3 PE=1 SV=1 8.49 2523.3 - 709279 - - - 4.8948 - 1.938 0.198 - 397.7 1 2 0 0.005 9 0 0 0 1.21E+07 4.21E+06 - - - 2.4161 0.9998 221125_WJC_METTL3_EV_vs_WT_F04.13210.13210.2 5.00E-05 14/24 K.QFLEC[160.03]AQNQGDIK.L "sp|Q5T1J5|CHCH9_HUMAN,sp|Q9Y6H1|CHCH2_HUMAN" 2 1549.7195 4.94 47360 13210 2 1549.716096 775.867 "Putative coiled-coil-helix-coiled-coil-helix domain-containing protein CHCHD2P9, mitochondrial OS=Homo sapiens OX=9606 GN=CHCHD2P9 PE=5 SV=1" 4.37 2523.5 - 449738 - - - -2.1914 - 2.673 0.542 - 990.1 1 2 0 -0.0034 13 0 0 0 4.46E+06 9.03E+05 - - - 5.5666 0.9962 221125_WJC_METTL3_EV_vs_WT_F04.13211.13211.3 0.0155 Oct-52 R.NALQQENHIIDGVK[136.11].V "sp|Q9GZT3|SLIRP_HUMAN,tr|H0YJW7|H0YJW7_HUMAN,tr|A0A087WUN7|A0A087WUN7_HUMAN,tr|G3V2S9|G3V2S9_HUMAN,tr|H0YJ40|H0YJ40_HUMAN,tr|G3V4X6|G3V4X6_HUMAN" 6 1585.8304 2.39 47361 13211 3 1585.830961 529.6174 "SRA stem-loop-interacting RNA-binding protein, mitochondrial OS=Homo sapiens OX=9606 GN=SLIRP PE=1 SV=1" 5.32 2523.7 - 381419 - - - 0.3733 - 1.73 0.217 - 151.2 1 2 0 0.0006 14 0 0 0 4.58E+06 1.91E+06 - - - 2.4158 0.8808 221125_WJC_METTL3_EV_vs_WT_F04.13212.13212.3 0.0219 Oct-48 K.TPAQLAGHMQTHL.G "tr|I3L0M3|I3L0M3_HUMAN,tr|I3L4Y2|I3L4Y2_HUMAN" 2 1403.698 - 47362 13212 3 1403.698218 468.9066 "MYC-associated zinc finger protein (Purine-binding transcription factor), isoform CRA_e OS=Homo sapiens OX=9606 GN=MAZ PE=1 SV=1" 6.61 2523.8 - 352049 - - - 0.1781 - 1.786 0.271 - 61.4 1 1 0 0.0002 13 0 0 0 - - - - - 3.1338 0.9995 221125_WJC_METTL3_EV_vs_WT_F04.13213.13213.3 0.00678 Sep-36 K.DMLQAASHYR.Q sp|Q8WUM0|NU133_HUMAN 1 1190.5502 1.28 47363 13213 3 1190.552083 397.8574 Nuclear pore complex protein Nup133 OS=Homo sapiens OX=9606 GN=NUP133 PE=1 SV=2 6.74 2523.9 - 300807 - - - 1.5463 - 1.982 0.316 - 82.5 1 2 0 0.0018 10 0 0 0 6.11E+06 4.78E+06 - - - 4.0605 0.9538 221125_WJC_METTL3_EV_vs_WT_F04.13214.13214.2 0.00109 20-Sep K.NR[166.11]PFMGSISQQ.N "sp|Q9NWS0|PIHD1_HUMAN,tr|M0QXD5|M0QXD5_HUMAN,tr|M0R3A4|M0R3A4_HUMAN,tr|M0R2P8|M0R2P8_HUMAN,tr|M0QYA2|M0QYA2_HUMAN" 5 1273.6113 1.62 47364 13214 2 1273.613967 637.8129 PIH1 domain-containing protein 1 OS=Homo sapiens OX=9606 GN=PIH1D1 PE=1 SV=1 9.75 2524.1 - 285254 - - - 2.1137 - 1.778 0.392 - 270.4 1 1 0 0.0027 11 0 0 0 4.49E+06 2.78E+06 - - - 3.4923 0.9998 221125_WJC_METTL3_EV_vs_WT_F04.13215.13215.2 0.0031 16-Oct R.QLQQLQQLR[166.11].D sp|O43290|SNUT1_HUMAN 1 1163.665 1.89 47365 13215 2 1163.665759 582.8398 U4\U6.U5 tri-snRNP-associated protein 1 OS=Homo sapiens OX=9606 GN=SART1 PE=1 SV=1 9.75 2524.2 - 284591 - - - 0.6308 - 2.208 0.377 - 409.2 1 2 0 0.0007 9 0 0 0 3.59E+06 1.90E+06 - - - 4.1168 0.996 221125_WJC_METTL3_EV_vs_WT_F04.13216.13216.3 0.000828 Aug-48 K.MGAYHTIELEPNR.Q sp|Q9BRX2|PELO_HUMAN 1 1529.7297 0.94 47366 13216 3 1529.725617 510.9172 Protein pelota homolog OS=Homo sapiens OX=9606 GN=PELO PE=1 SV=2 5.38 2524.3 - 267636 - - - -2.6449 - 1.863 0.255 - 85.4 1 2 0 -0.004 13 0 0 0 3.50E+06 3.71E+06 - - - 3.0688 0.9891 221125_WJC_METTL3_EV_vs_WT_F04.13220.13220.2 7.01E-05 16-Sep K.NMSVHLSPC[160.03].F "sp|P62280|RS11_HUMAN,tr|M0R1H5|M0R1H5_HUMAN,tr|M0QZC5|M0QZC5_HUMAN" 3 1043.4528 - 47369 13220 2 1043.453332 522.7337 40S ribosomal protein S11 OS=Homo sapiens OX=9606 GN=RPS11 PE=1 SV=3 6.73 2524.8 - 1.16E+06 - - - 0.4753 - 1.658 0.515 - 249.8 1 1 0 0.0005 9 0 0 0 - - - - - 4.3074 0.9999 221125_WJC_METTL3_EV_vs_WT_F04.13222.13222.3 2.01E-05 Nov-40 K.MK[136.11]EIAEAYLGK[136.11].T "sp|P11142|HSP7C_HUMAN,tr|E9PQQ4|E9PQQ4_HUMAN,tr|E9PKE3|E9PKE3_HUMAN,tr|E9PN89|E9PN89_HUMAN,tr|E9PLF4|E9PLF4_HUMAN,tr|E9PI65|E9PI65_HUMAN,tr|E9PK54|E9PK54_HUMAN,tr|E9PPY6|E9PPY6_HUMAN,tr|E9PQK7|E9PQK7_HUMAN" 9 1267.6817 0.16 47370 13222 3 1267.682487 423.5678 Heat shock cognate 71 kDa protein OS=Homo sapiens OX=9606 GN=HSPA8 PE=1 SV=1 5.9 2525 - 3.91E+06 - - - 0.6129 - 2.336 0.492 - 216.2 1 2 1 0.0008 11 0 0 0 3.66E+08 2.28E+09 - - - 6.4354 0.9998 221125_WJC_METTL3_EV_vs_WT_F04.13224.13224.2 4.08E-05 20-Oct R.VSFC[160.03]APGPPGR.S "sp|Q8IY67|RAVR1_HUMAN,tr|E9PAU2|E9PAU2_HUMAN,tr|A0A087WZ13|A0A087WZ13_HUMAN" 3 1143.5495 0.88 47372 13224 2 1143.550674 572.782 Ribonucleoprotein PTB-binding 1 OS=Homo sapiens OX=9606 GN=RAVER1 PE=1 SV=1 8.22 2525.1 - 4.66E+06 - - - 1.0153 - 1.897 0.47 - 216.8 1 2 0 0.0012 11 0 0 0 1.42E+08 1.61E+08 - - - 4.2441 0.9999 221125_WJC_METTL3_EV_vs_WT_F04.13225.13225.3 0.00149 Nov-36 K.LK[136.11]EENFFGPK[136.11].E sp|Q9NZI8|IF2B1_HUMAN 1 1223.6521 1.61 47373 13225 3 1223.652442 408.8913 Insulin-like growth factor 2 mRNA-binding protein 1 OS=Homo sapiens OX=9606 GN=IGF2BP1 PE=1 SV=2 6.14 2525.2 - 1.92E+06 - - - 0.2599 - 2.072 0.536 - 140.2 1 2 1 0.0003 10 0 0 0 2.79E+08 1.73E+08 - - - 6.6434 1 221125_WJC_METTL3_EV_vs_WT_F04.13228.13228.2 1.56E-06 13/20 R.DSDLAAESNFR.L sp|P09629|HXB7_HUMAN 1 1223.5418 0.34 47376 13228 2 1223.542083 612.7782 Homeobox protein Hox-B7 OS=Homo sapiens OX=9606 GN=HOXB7 PE=1 SV=4 4.03 2525.5 - 616808 - - - 0.1945 - 2.275 0.632 - 592.2 1 2 0 0.0002 11 0 0 0 5.02E+06 1.49E+07 - - - 5.9325 0.9863 221125_WJC_METTL3_EV_vs_WT_F04.13229.13229.2 0.00257 18-Sep K.GLSQSALPYR[166.11].R "sp|P62277|RS13_HUMAN,tr|J3KMX5|J3KMX5_HUMAN,tr|E9PS50|E9PS50_HUMAN" 3 1100.5854 0.19 47377 13229 2 1100.591186 551.3 40S ribosomal protein S13 OS=Homo sapiens OX=9606 GN=RPS13 PE=1 SV=2 8.75 2525.7 - 556329 - - - 5.2772 - 1.97 0.264 - 338.3 1 2 0 0.0058 10 0 0 0 4.85E+06 2.51E+07 - - - 2.8817 0.9981 221125_WJC_METTL3_EV_vs_WT_F04.13230.13230.2 1.48E-05 14/20 K.MK[136.11]EIAEAYLGK[136.11].T "sp|P11142|HSP7C_HUMAN,tr|E9PQQ4|E9PQQ4_HUMAN,tr|E9PKE3|E9PKE3_HUMAN,tr|E9PN89|E9PN89_HUMAN,tr|E9PLF4|E9PLF4_HUMAN,tr|E9PI65|E9PI65_HUMAN,tr|E9PK54|E9PK54_HUMAN,tr|E9PPY6|E9PPY6_HUMAN,tr|E9PQK7|E9PQK7_HUMAN" 9 1267.6817 0.16 47378 13230 2 1267.683958 634.8481 Heat shock cognate 71 kDa protein OS=Homo sapiens OX=9606 GN=HSPA8 PE=1 SV=1 5.9 2525.8 - 520048 - - - 1.7733 - 2.689 0.525 - 483.4 1 2 1 0.0022 11 0 0 0 7.15E+07 4.51E+08 - - - 5.5939 1 221125_WJC_METTL3_EV_vs_WT_F04.13231.13231.2 2.41E-08 22-Dec K.MEVDYSATVDQR.L "sp|O00232|PSD12_HUMAN,tr|J3KTJ5|J3KTJ5_HUMAN,tr|J3KSK1|J3KSK1_HUMAN" 3 1412.6242 1.07 47379 13231 2 1412.623957 707.3194 26S proteasome non-ATPase regulatory subunit 12 OS=Homo sapiens OX=9606 GN=PSMD12 PE=1 SV=3 4.03 2525.9 - 485735 - - - -0.1678 - 2.71 0.717 - 576.5 1 2 0 -0.0002 12 0 0 0 8.80E+06 8.25E+06 - - - 6.9598 1 221125_WJC_METTL3_EV_vs_WT_F04.13232.13232.2 1.04E-10 13/22 K.MEVDYSATVDQR[166.11].L "sp|O00232|PSD12_HUMAN,tr|J3KTJ5|J3KTJ5_HUMAN,tr|J3KSK1|J3KSK1_HUMAN" 3 1422.6325 1.05 47380 13232 2 1422.626356 712.3235 26S proteasome non-ATPase regulatory subunit 12 OS=Homo sapiens OX=9606 GN=PSMD12 PE=1 SV=3 4.03 2526.1 - 463911 - - - -4.2934 - 2.738 0.676 - 650.3 1 2 0 -0.0061 12 0 0 0 8.66E+06 8.25E+06 - - - 6.6822 0.9999 221125_WJC_METTL3_EV_vs_WT_F04.13233.13233.3 3.09E-06 Dec-40 K.VYNYNHLMPTR[166.11].Y "sp|P61353|RL27_HUMAN,tr|K7ELC7|K7ELC7_HUMAN" 2 1416.6848 0.87 47381 13233 3 1416.687462 473.2355 60S ribosomal protein L27 OS=Homo sapiens OX=9606 GN=RPL27 PE=1 SV=2 8.57 2526.2 - 331820 - - - 1.8967 - 2.234 0.489 - 170 1 2 0 0.0027 11 0 0 0 1.08E+08 1.24E+08 - - - 6.2746 0.9998 221125_WJC_METTL3_EV_vs_WT_F04.13234.13234.2 0.057 20-Aug K.ADFQYQESNLR.T "sp|Q5HYJ3|FA76B_HUMAN,tr|F5GX09|F5GX09_HUMAN" 2 1369.6262 0.63 47382 13234 2 1369.626837 685.8204 Protein FAM76B OS=Homo sapiens OX=9606 GN=FAM76B PE=1 SV=3 4.37 2526.3 - 318337 - - - 0.4337 - 1.612 0.499 - 160 1 2 0 0.0006 11 0 0 0 2.17E+06 3.45E+06 - - - 4.0181 1 221125_WJC_METTL3_EV_vs_WT_F04.13240.13240.2 1.90E-08 28-Nov K.TFTTQETITNAETAK.E "sp|P06744|G6PI_HUMAN,tr|A0A2R8Y6C7|A0A2R8Y6C7_HUMAN,tr|A0A0J9YYH3|A0A0J9YYH3_HUMAN,tr|K7EQ48|K7EQ48_HUMAN,tr|A0A2U3TZU2|A0A2U3TZU2_HUMAN,tr|K7ERC6|K7ERC6_HUMAN,tr|A0A0J9YXP8|A0A0J9YXP8_HUMAN,tr|A0A0J9YX90|A0A0J9YX90_HUMAN" 8 1654.805 1.02 47388 13240 2 1654.810289 828.4098 Glucose-6-phosphate isomerase OS=Homo sapiens OX=9606 GN=GPI PE=1 SV=4 4.53 2527.1 - 123270 - - - 3.1986 - 2.163 0.67 - 306.6 1 2 0 0.0053 15 0 0 0 1.00E+06 9.81E+05 - - - 5.8847 0.9998 221125_WJC_METTL3_EV_vs_WT_F04.13242.13242.2 0.00155 22-Oct R.ETLPAEQDLTTK.N "sp|P25786|PSA1_HUMAN,tr|F5GX11|F5GX11_HUMAN" 2 1344.6773 2.25 47389 13242 2 1344.678104 673.3459 Proteasome subunit alpha type-1 OS=Homo sapiens OX=9606 GN=PSMA1 PE=1 SV=1 4.14 2527.3 - 1.08E+06 - - - 0.6158 - 2.085 0.44 - 330.2 1 2 0 0.0008 12 0 0 0 1.49E+08 6.64E+07 - - - 4.2239 0.9997 221125_WJC_METTL3_EV_vs_WT_F04.13244.13244.3 0.000415 Nov-36 K.LKEENFFGPK.E sp|Q9NZI8|IF2B1_HUMAN 1 1207.6237 1.62 47390 13244 3 1207.624938 403.5485 Insulin-like growth factor 2 mRNA-binding protein 1 OS=Homo sapiens OX=9606 GN=IGF2BP1 PE=1 SV=2 6.14 2527.5 - 1.14E+07 - - - 1.0053 - 2.185 0.45 - 138.6 1 2 1 0.0012 10 0 0 0 2.76E+08 1.70E+08 - - - 5.8394 0.9996 221125_WJC_METTL3_EV_vs_WT_F04.13246.13246.3 0.000219 Dec-40 K.MKEIAEAYLGK.T "sp|P11142|HSP7C_HUMAN,tr|E9PQQ4|E9PQQ4_HUMAN,tr|E9PKE3|E9PKE3_HUMAN,tr|E9PN89|E9PN89_HUMAN,tr|E9PLF4|E9PLF4_HUMAN,tr|E9PI65|E9PI65_HUMAN,tr|E9PK54|E9PK54_HUMAN,tr|E9PPY6|E9PPY6_HUMAN,tr|E9PQK7|E9PQK7_HUMAN" 9 1251.6533 0.16 47392 13246 3 1251.653906 418.225 Heat shock cognate 71 kDa protein OS=Homo sapiens OX=9606 GN=HSPA8 PE=1 SV=1 5.9 2527.6 - 2.97E+06 - - - 0.4762 - 2.201 0.402 - 262.5 1 2 1 0.0006 11 0 0 0 3.67E+08 2.29E+09 - - - 5.2629 0.9909 221125_WJC_METTL3_EV_vs_WT_F04.13247.13247.2 0.00771 18-Oct R.NLQDAMQVC[160.03]R[166.11].N "sp|P49368|TCPG_HUMAN,tr|B4DUR8|B4DUR8_HUMAN" 2 1243.5677 0.14 47393 13247 2 1243.571587 622.7911 T-complex protein 1 subunit gamma OS=Homo sapiens OX=9606 GN=CCT3 PE=1 SV=4 5.83 2527.7 - 2.02E+06 - - - 3.1289 - 2.019 0.118 - 388.9 1 2 0 0.0039 10 0 0 0 1.43E+07 1.02E+08 - - - 1.8725 0.9991 221125_WJC_METTL3_EV_vs_WT_F04.13248.13248.3 0.00128 Sep-40 R.DVDPGEHYILK.T "sp|P05089|ARGI1_HUMAN,tr|A0A5F9ZGN6|A0A5F9ZGN6_HUMAN" 2 1284.635 22.3 47394 13248 3 1284.63115 429.2189 Arginase-1 OS=Homo sapiens OX=9606 GN=ARG1 PE=1 SV=2 4.54 2527.8 - 1.94E+06 - - - -3.0102 - 1.813 0.379 - 82.3 1 2 0 -0.0039 11 0 0 0 6.78E+07 3.04E+06 - - - 4.4546 1 221125_WJC_METTL3_EV_vs_WT_F04.13249.13249.2 3.42E-06 15/24 R.IEDVTPIPSDSTR.R "sp|P62263|RS14_HUMAN,tr|A0A2R8Y811|A0A2R8Y811_HUMAN" 2 1428.7096 1.5 47395 13249 2 1428.70982 715.3621 40S ribosomal protein S14 OS=Homo sapiens OX=9606 GN=RPS14 PE=1 SV=3 4.03 2527.8 - 1.68E+06 - - - 0.1267 - 2.876 0.578 - 752.5 1 2 0 0.0002 13 0 0 0 4.66E+09 3.10E+09 - - - 6.0213 0.9967 221125_WJC_METTL3_EV_vs_WT_F04.13250.13250.2 0.00168 18-Oct K.LK[136.11]EENFFGPK[136.11].E sp|Q9NZI8|IF2B1_HUMAN 1 1223.6521 1.38 47396 13250 2 1223.653556 612.8333 Insulin-like growth factor 2 mRNA-binding protein 1 OS=Homo sapiens OX=9606 GN=IGF2BP1 PE=1 SV=2 6.14 2527.9 - 1.23E+06 - - - 1.1703 - 1.947 0.427 - 233.3 1 2 1 0.0014 10 0 0 0 4.28E+07 3.11E+07 - - - 4.0542 0.9999 221125_WJC_METTL3_EV_vs_WT_F04.13251.13251.3 6.99E-08 20/52 R.VAVEEVDEEGK[136.11]FVR[166.11].L "sp|P02545|LMNA_HUMAN,tr|A0A804HL68|A0A804HL68_HUMAN,tr|Q5TCI8|Q5TCI8_HUMAN,tr|A0A6Q8PFJ0|A0A6Q8PFJ0_HUMAN,tr|A0A6Q8PHQ9|A0A6Q8PHQ9_HUMAN" 5 1622.8271 2.03 47397 13251 3 1622.829004 541.9496 Prelamin-A\C OS=Homo sapiens OX=9606 GN=LMNA PE=1 SV=1 4.25 2528 - 910489 - - - 1.1905 - 3.755 0.542 - 745.2 1 2 1 0.0019 14 0 0 0 1.87E+07 9.24E+06 - - - 8.0984 1 221125_WJC_METTL3_EV_vs_WT_F04.13252.13252.2 3.61E-10 28-Oct R.YSGAYGASVSDEELK.R "sp|Q9NX63|MIC19_HUMAN,tr|A0A286YEX5|A0A286YEX5_HUMAN,tr|F8WAR4|F8WAR4_HUMAN,tr|C9JRZ6|C9JRZ6_HUMAN" 4 1574.71 2.01 47398 13252 2 1574.712479 788.3623 MICOS complex subunit MIC19 OS=Homo sapiens OX=9606 GN=CHCHD3 PE=1 SV=1 4.14 2528.2 - 676399 - - - 1.5533 - 2.709 0.62 - 185.3 1 2 0 0.0024 15 0 0 0 1.60E+08 7.95E+07 - - - 6.0697 0.9864 221125_WJC_METTL3_EV_vs_WT_F04.13253.13253.2 0.117 20-Jul R.DVDPGEHYILK.T "sp|P05089|ARGI1_HUMAN,tr|A0A5F9ZGN6|A0A5F9ZGN6_HUMAN" 2 1284.635 14.43 47399 13253 2 1284.631836 643.3248 Arginase-1 OS=Homo sapiens OX=9606 GN=ARG1 PE=1 SV=2 4.54 2528.3 - 532634 - - - -2.4762 - 1.565 0.125 - 94.6 1 2 0 -0.0032 11 0 0 0 2.05E+07 1.42E+06 - - - 1.1749 0.9998 221125_WJC_METTL3_EV_vs_WT_F04.13254.13254.2 1.12E-06 26-Dec K.GADSELSTVPSVTK.T sp|P46087|NOP2_HUMAN 1 1389.6987 0.25 47400 13254 2 1389.69793 695.8566 Probable 28S rRNA (cytosine(4447)-C(5))-methyltransferase OS=Homo sapiens OX=9606 GN=NOP2 PE=1 SV=2 4.37 2528.4 - 492232 - - - -0.5829 - 2.639 0.418 - 321.3 1 2 0 -0.0008 14 0 0 0 8.11E+06 3.25E+07 - - - 4.5633 0.9999 221125_WJC_METTL3_EV_vs_WT_F04.13255.13255.2 3.38E-06 26-Dec K.GADSELSTVPSVTK[136.11].T sp|P46087|NOP2_HUMAN 1 1397.7129 0.25 47401 13255 2 1397.711297 699.8637 Probable 28S rRNA (cytosine(4447)-C(5))-methyltransferase OS=Homo sapiens OX=9606 GN=NOP2 PE=1 SV=2 4.37 2528.6 - 470783 - - - -1.1755 - 2.799 0.493 - 400.5 1 2 0 -0.0016 14 0 0 0 8.19E+06 3.25E+07 - - - 5.2647 0.98 221125_WJC_METTL3_EV_vs_WT_F04.13256.13256.3 0.0282 Oct-40 Q.WLPEVTK[136.11]PEGK[136.11].D "sp|Q16576|RBBP7_HUMAN,tr|C9J7L0|C9J7L0_HUMAN,tr|E9PC52|E9PC52_HUMAN" 3 1298.7205 0.92 47402 13256 3 1298.721016 433.9141 Histone-binding protein RBBP7 OS=Homo sapiens OX=9606 GN=RBBP7 PE=1 SV=1 6.14 2528.7 - 409320 - - - 0.3681 - 1.97 0.37 - 127.9 1 1 0 0.0005 11 0 0 0 5.69E+06 6.21E+06 - - - 4.5912 0.9983 221125_WJC_METTL3_EV_vs_WT_F04.13257.13257.2 0.0249 18-Sep R.SGEPQTFTLK.F "sp|P05556|ITB1_HUMAN,tr|Q5T3E6|Q5T3E6_HUMAN,tr|A0A7I2V2F9|A0A7I2V2F9_HUMAN,tr|A0A7I2V5T3|A0A7I2V5T3_HUMAN,tr|H7C4K3|H7C4K3_HUMAN,tr|E7EQW5|E7EQW5_HUMAN,tr|E9PLR6|E9PLR6_HUMAN,tr|E7EUI6|E7EUI6_HUMAN,tr|A0A7I2V5Z8|A0A7I2V5Z8_HUMAN,tr|A0A7I2V348|A0A7I2V348_HUMAN,tr|C9JPK5|C9JPK5_HUMAN" 11 1106.5608 0.84 47403 13257 2 1106.56255 554.2877 Integrin beta-1 OS=Homo sapiens OX=9606 GN=ITGB1 PE=1 SV=2 5.72 2528.8 - 371677 - - - 1.5914 - 1.615 0.275 - 195.9 1 2 0 0.0018 10 0 0 0 6.47E+06 7.74E+06 - - - 2.4096 1 221125_WJC_METTL3_EV_vs_WT_F04.13259.13259.3 4.37E-07 21/64 K.VGSLDNVGHLPAGGAVK.T "sp|P27816|MAP4_HUMAN,tr|H0Y2V1|H0Y2V1_HUMAN,tr|E7EVA0|E7EVA0_HUMAN,tr|F8W9U4|F8W9U4_HUMAN,tr|H7C4C5|H7C4C5_HUMAN,tr|A0A804HKE7|A0A804HKE7_HUMAN" 6 1589.8526 0.45 47405 13259 3 1589.85337 530.9581 Microtubule-associated protein 4 OS=Homo sapiens OX=9606 GN=MAP4 PE=1 SV=3 6.71 2529 - 334767 - - - 0.5126 - 2.769 0.503 - 496 1 2 0 0.0008 17 0 0 0 4.11E+06 9.07E+06 - - - 6.7207 0.9999 221125_WJC_METTL3_EV_vs_WT_F04.13265.13265.2 9.12E-05 22-Nov R.AQPSVSLGAAYR.A sp|Q96PK6|RBM14_HUMAN 1 1218.6357 1.87 47410 13265 2 1218.635409 610.3251 RNA-binding protein 14 OS=Homo sapiens OX=9606 GN=RBM14 PE=1 SV=2 8.79 2529.7 - 2.62E+06 - - - -0.2273 - 2.148 0.481 - 457.7 1 2 0 -0.0003 12 0 0 0 8.05E+08 4.31E+08 - - - 4.6052 0.9495 221125_WJC_METTL3_EV_vs_WT_F04.13266.13266.3 0.166 Aug-40 K.MKEIAEAYLGK[136.11].T "sp|P11142|HSP7C_HUMAN,tr|E9PQQ4|E9PQQ4_HUMAN,tr|E9PKE3|E9PKE3_HUMAN,tr|E9PN89|E9PN89_HUMAN,tr|E9PLF4|E9PLF4_HUMAN,tr|E9PI65|E9PI65_HUMAN,tr|E9PK54|E9PK54_HUMAN,tr|E9PPY6|E9PPY6_HUMAN,tr|E9PQK7|E9PQK7_HUMAN" 9 1259.6675 - 47411 13266 3 1259.667294 420.8964 Heat shock cognate 71 kDa protein OS=Homo sapiens OX=9606 GN=HSPA8 PE=1 SV=1 5.9 2529.8 - 2.06E+06 - - - -0.1715 - 1.677 0.154 - 84.4 1 2 1 -0.0002 11 0 0 0 - - - - - 1.7256 1 221125_WJC_METTL3_EV_vs_WT_F04.13267.13267.2 7.04E-07 16/28 R.YSGAYGASVSDEELK[136.11].R "sp|Q9NX63|MIC19_HUMAN,tr|A0A286YEX5|A0A286YEX5_HUMAN,tr|F8WAR4|F8WAR4_HUMAN,tr|C9JRZ6|C9JRZ6_HUMAN" 4 1582.7242 2.01 47412 13267 2 1582.723908 792.3694 MICOS complex subunit MIC19 OS=Homo sapiens OX=9606 GN=CHCHD3 PE=1 SV=1 4.14 2529.8 - 1.95E+06 - - - -0.2053 - 3.262 0.679 - 602.8 1 2 0 -0.0003 15 0 0 0 1.59E+08 7.88E+07 - - - 6.9628 0.9971 221125_WJC_METTL3_EV_vs_WT_F04.13268.13268.2 1.18E-05 20-Dec K.MKEIAEAYLGK.T "sp|P11142|HSP7C_HUMAN,tr|E9PQQ4|E9PQQ4_HUMAN,tr|E9PKE3|E9PKE3_HUMAN,tr|E9PN89|E9PN89_HUMAN,tr|E9PLF4|E9PLF4_HUMAN,tr|E9PI65|E9PI65_HUMAN,tr|E9PK54|E9PK54_HUMAN,tr|E9PPY6|E9PPY6_HUMAN,tr|E9PQK7|E9PQK7_HUMAN" 9 1251.6533 0.16 47413 13268 2 1251.65315 626.8339 Heat shock cognate 71 kDa protein OS=Homo sapiens OX=9606 GN=HSPA8 PE=1 SV=1 5.9 2529.9 - 1.68E+06 - - - -0.1278 - 2.386 0.319 - 325.6 1 2 1 -0.0002 11 0 0 0 7.15E+07 4.51E+08 - - - 3.7496 0.9999 221125_WJC_METTL3_EV_vs_WT_F04.13271.13271.2 1.71E-06 15/22 K.QGEEEDAEIIVK.L "sp|Q9UHX1|PUF60_HUMAN,tr|A0A0J9YYL3|A0A0J9YYL3_HUMAN,tr|A0A0J9YXX5|A0A0J9YXX5_HUMAN,tr|A0A0J9YXJ8|A0A0J9YXJ8_HUMAN,tr|A0A0J9YVP6|A0A0J9YVP6_HUMAN" 5 1358.6565 2.14 47416 13271 2 1358.654454 680.3355 Poly(U)-binding-splicing factor PUF60 OS=Homo sapiens OX=9606 GN=PUF60 PE=1 SV=1 3.91 2530.2 - 604913 - - - -1.5353 - 2.604 0.545 - 757.8 1 2 0 -0.0021 12 0 0 0 6.56E+07 3.07E+07 - - - 5.5839 0.9931 221125_WJC_METTL3_EV_vs_WT_F04.13272.13272.2 2.91E-06 24-Oct L.SGGTTMYPGIADR.M "sp|P63261|ACTG_HUMAN,sp|P68133|ACTS_HUMAN,sp|P62736|ACTA_HUMAN,sp|P68032|ACTC_HUMAN,sp|P60709|ACTB_HUMAN,sp|P63267|ACTH_HUMAN,tr|A0A2R8YFE2|A0A2R8YFE2_HUMAN,tr|A0A804GS07|A0A804GS07_HUMAN,tr|E7EVS6|E7EVS6_HUMAN,tr|A0A6Q8PFE4|A0A6Q8PFE4_HUMAN,tr|A0A804HKV3|A0A804HKV3_HUMAN,tr|A0A2R8Y793|A0A2R8Y793_HUMAN,tr|I3L4N8|I3L4N8_HUMAN,tr|A6NL76|A6NL76_HUMAN" 14 1324.6082 2.19 47417 13272 2 1324.608548 663.3114 "Actin, cytoplasmic 2 OS=Homo sapiens OX=9606 GN=ACTG1 PE=1 SV=1" 5.55 2530.3 - 597302 - - - 0.3005 - 2.062 0.555 - 298.5 1 1 0 0.0004 13 0 0 0 1.20E+07 5.46E+06 - - - 4.9974 0.9464 221125_WJC_METTL3_EV_vs_WT_F04.13273.13273.3 0.0338 Jul-36 K.LKEENFFGPK[136.11].E sp|Q9NZI8|IF2B1_HUMAN 1 1215.6379 - 47418 13273 3 1215.636772 406.2199 Insulin-like growth factor 2 mRNA-binding protein 1 OS=Homo sapiens OX=9606 GN=IGF2BP1 PE=1 SV=2 6.14 2530.5 - 467892 - - - -0.9477 - 1.693 0.157 - 44.8 2 2 1 -0.0012 10 0 0 0 - - - - - 1.6884 0.9998 221125_WJC_METTL3_EV_vs_WT_F04.13274.13274.2 4.52E-06 24-Nov R.IDSGSEVIVGVNK.Y sp|P22033|MUTA_HUMAN 1 1315.6983 2.14 47419 13274 2 1315.698126 658.8564 "Methylmalonyl-CoA mutase, mitochondrial OS=Homo sapiens OX=9606 GN=MMUT PE=1 SV=4" 4.37 2530.6 - 438522 - - - -0.1672 - 2.063 0.479 - 291 1 2 0 -0.0002 13 0 0 0 2.68E+06 1.25E+06 - - - 4.4374 0.9997 221125_WJC_METTL3_EV_vs_WT_F04.13275.13275.2 0.000203 18-Oct K.SYSQSSNLFR[166.11].H sp|P17028|ZNF24_HUMAN 1 1197.5654 1.4 47420 13275 2 1197.563281 599.79 Zinc finger protein 24 OS=Homo sapiens OX=9606 GN=ZNF24 PE=1 SV=4 8.46 2530.7 - 332913 - - - -1.7452 - 1.836 0.462 - 306.1 1 2 0 -0.0021 10 0 0 0 3.25E+07 2.33E+07 - - - 4.1486 0.7968 221125_WJC_METTL3_EV_vs_WT_F04.13278.13278.2 0.00396 28-Aug R.LAAEGQAIDGAELSK.G "sp|Q9Y2I8|WDR37_HUMAN,tr|A0A087WTQ2|A0A087WTQ2_HUMAN,tr|E7EQ49|E7EQ49_HUMAN,tr|C9JGR9|C9JGR9_HUMAN,tr|A0A3B3IT47|A0A3B3IT47_HUMAN" 5 1471.7518 6.77 47423 13278 2 1471.737652 736.8832 WD repeat-containing protein 37 OS=Homo sapiens OX=9606 GN=WDR37 PE=1 SV=2 4.14 2531.1 - 153454 - - - -9.6389 - 1.487 0.262 - 88.5 1 2 0 -0.0142 15 0 0 0 1.44E+06 2.13E+05 - - - 1.9471 0.9997 221125_WJC_METTL3_EV_vs_WT_F04.13281.13281.2 1.27E-06 24-Nov R.IEDVTPIPSDSTR[166.11].R "sp|P62263|RS14_HUMAN,tr|A0A2R8Y811|A0A2R8Y811_HUMAN" 2 1438.7179 1.5 47424 13281 2 1438.721364 720.3662 40S ribosomal protein S14 OS=Homo sapiens OX=9606 GN=RPS14 PE=1 SV=3 4.03 2531.5 - 1.68E+07 - - - 2.4014 - 2.453 0.581 - 316.5 1 2 0 0.0035 13 0 0 0 4.66E+09 3.10E+09 - - - 5.6342 1 221125_WJC_METTL3_EV_vs_WT_F04.13282.13282.2 3.89E-08 18/32 R.AIGGGLSSVGGGSSTIK.Y "sp|P48668|K2C6C_HUMAN,sp|P02538|K2C6A_HUMAN" 2 1446.7678 11228.32 47425 13282 2 1446.768642 724.3912 "Keratin, type II cytoskeletal 6C OS=Homo sapiens OX=9606 GN=KRT6C PE=1 SV=3" 8.8 2531.6 - 8.14E+06 - - - 0.5668 - 3.111 0.576 - 845.8 1 2 0 0.0008 17 0 0 0 6.58E+09 5.86E+05 - - - 6.0854 1 221125_WJC_METTL3_EV_vs_WT_F04.13285.13285.3 1.00E-07 14/40 K.VYNYNHLMPTR.Y "sp|P61353|RL27_HUMAN,tr|K7ELC7|K7ELC7_HUMAN" 2 1406.6765 0.86 47428 13285 3 1406.675576 469.8994 60S ribosomal protein L27 OS=Homo sapiens OX=9606 GN=RPL27 PE=1 SV=2 8.57 2531.8 - 1.78E+06 - - - -0.6604 - 2.431 0.599 - 254 1 2 0 -0.0009 11 0 0 0 1.09E+08 1.27E+08 - - - 7.7415 0.9999 221125_WJC_METTL3_EV_vs_WT_F04.13286.13286.3 0.000117 14/48 R.IEDVTPIPSDSTR.R "sp|P62263|RS14_HUMAN,tr|A0A2R8Y811|A0A2R8Y811_HUMAN" 2 1428.7096 1.45 47429 13286 3 1428.708826 477.2438 40S ribosomal protein S14 OS=Homo sapiens OX=9606 GN=RPS14 PE=1 SV=3 4.03 2531.8 - 1.71E+06 - - - -0.569 - 2.269 0.383 - 370.3 1 2 0 -0.0008 13 0 0 0 2.27E+08 1.56E+08 - - - 5.0313 0.9998 221125_WJC_METTL3_EV_vs_WT_F04.13287.13287.2 1.99E-06 18-Oct R.NLQDAMQVC[160.03]R.N "sp|P49368|TCPG_HUMAN,tr|B4DUR8|B4DUR8_HUMAN" 2 1233.5594 0.14 47430 13287 2 1233.561584 617.787 T-complex protein 1 subunit gamma OS=Homo sapiens OX=9606 GN=CCT3 PE=1 SV=4 5.83 2531.9 - 1.22E+06 - - - 1.7494 - 2.151 0.524 - 389.9 1 2 0 0.0022 10 0 0 0 1.40E+07 1.02E+08 - - - 5.0485 0.9993 221125_WJC_METTL3_EV_vs_WT_F04.13288.13288.3 0.00267 14/48 R.IEDVTPIPSDSTR[166.11].R "sp|P62263|RS14_HUMAN,tr|A0A2R8Y811|A0A2R8Y811_HUMAN" 2 1438.7179 1.47 47431 13288 3 1438.716908 480.5799 40S ribosomal protein S14 OS=Homo sapiens OX=9606 GN=RPS14 PE=1 SV=3 4.03 2532 - 1.20E+06 - - - -0.6958 - 1.604 0.341 - 196.2 1 2 0 -0.001 13 0 0 0 2.26E+08 1.54E+08 - - - 3.6226 0.9998 221125_WJC_METTL3_EV_vs_WT_F04.13290.13290.2 2.35E-05 20-Dec R.QVADQMWQAGK.R "sp|Q9GZM5|YIPF3_HUMAN,tr|D6RGY8|D6RGY8_HUMAN,tr|E7EQR8|E7EQR8_HUMAN,tr|D6RFI3|D6RFI3_HUMAN" 4 1260.5921 3.44 47433 13290 2 1260.593533 631.3033 Protein YIPF3 OS=Homo sapiens OX=9606 GN=YIPF3 PE=1 SV=1 5.84 2532.3 - 928015 - - - 1.132 - 1.969 0.48 - 359.5 1 2 0 0.0014 11 0 0 0 6.21E+06 1.81E+06 - - - 4.4187 0.9831 221125_WJC_METTL3_EV_vs_WT_F04.13293.13293.2 5.16E-05 24-Sep L.SGGTTMYPGIADR[166.11].M "sp|P63261|ACTG_HUMAN,sp|P68133|ACTS_HUMAN,sp|P62736|ACTA_HUMAN,sp|P68032|ACTC_HUMAN,sp|P60709|ACTB_HUMAN,sp|P63267|ACTH_HUMAN,tr|A0A2R8YFE2|A0A2R8YFE2_HUMAN,tr|A0A804GS07|A0A804GS07_HUMAN,tr|E7EVS6|E7EVS6_HUMAN,tr|A0A6Q8PFE4|A0A6Q8PFE4_HUMAN,tr|A0A804HKV3|A0A804HKV3_HUMAN,tr|A0A2R8Y793|A0A2R8Y793_HUMAN,tr|I3L4N8|I3L4N8_HUMAN,tr|A6NL76|A6NL76_HUMAN" 14 1334.6164 1.92 47436 13293 2 1334.618508 668.3155 "Actin, cytoplasmic 2 OS=Homo sapiens OX=9606 GN=ACTG1 PE=1 SV=1" 5.55 2532.6 - 676886 - - - 1.5645 - 1.748 0.531 - 237.4 1 1 0 0.0021 13 0 0 0 9.60E+06 4.99E+06 - - - 4.3956 0.9979 221125_WJC_METTL3_EV_vs_WT_F04.13294.13294.2 6.32E-05 24-Nov K.LDPGSEETQTLVR[166.11].E sp|P26641|EF1G_HUMAN 1 1453.7288 40.71 47437 13294 2 1453.735352 727.8717 Elongation factor 1-gamma OS=Homo sapiens OX=9606 GN=EEF1G PE=1 SV=3 4.14 2532.7 - 521292 - - - 4.5015 - 2.183 0.468 - 375.6 1 2 0 0.0065 13 0 0 0 1.32E+08 3.25E+06 - - - 4.4993 0.9994 221125_WJC_METTL3_EV_vs_WT_F04.13295.13295.2 0.000465 26-Oct R.FYEQMNGPVAGASR[166.11].Q "sp|P29692|EF1D_HUMAN,tr|E9PI39|E9PI39_HUMAN,tr|E9PMW7|E9PMW7_HUMAN,tr|E9PKK3|E9PKK3_HUMAN,tr|E9PQ49|E9PQ49_HUMAN,tr|A0A087X1X7|A0A087X1X7_HUMAN,tr|E9PL12|E9PL12_HUMAN,tr|E9PK72|E9PK72_HUMAN,tr|H0YCK7|H0YCK7_HUMAN,tr|E9PQZ1|E9PQZ1_HUMAN,tr|E9PK06|E9PK06_HUMAN,tr|E9PIZ1|E9PIZ1_HUMAN,tr|E9PN91|E9PN91_HUMAN,tr|E9PPR1|E9PPR1_HUMAN,tr|E9PRY8|E9PRY8_HUMAN,tr|E9PK01|E9PK01_HUMAN,tr|E9PL71|E9PL71_HUMAN" 17 1535.7066 1.23 47438 13295 2 1535.702793 768.8606 Elongation factor 1-delta OS=Homo sapiens OX=9606 GN=EEF1D PE=1 SV=5 6 2532.9 - 375734 - - - -2.4998 - 1.956 0.466 - 223.4 1 2 0 -0.0038 14 0 0 0 6.21E+07 5.04E+07 - - - 4.1653 0.9999 221125_WJC_METTL3_EV_vs_WT_F04.13298.13298.3 0.00013 Dec-40 R.KLQEALEFETK.R sp|Q9UI36|DACH1_HUMAN 1 1334.7082 1.03 47440 13298 3 1334.706887 445.91 Dachshund homolog 1 OS=Homo sapiens OX=9606 GN=DACH1 PE=1 SV=4 4.79 2533.2 - 1.33E+06 - - - -0.9702 - 2.199 0.423 - 196.2 1 2 0 -0.0013 11 0 0 0 2.11E+07 2.06E+07 - - - 5.4943 0.9972 221125_WJC_METTL3_EV_vs_WT_F04.13300.13300.2 0.0893 24-Jul K.GGSGSGPTIEEVD.- "sp|P0DMV8|HS71A_HUMAN,sp|P0DMV9|HS71B_HUMAN,tr|V9GZ37|V9GZ37_HUMAN,tr|A0A0G2JIW1|A0A0G2JIW1_HUMAN" 4 1203.5255 - 47441 13300 2 1203.52377 602.77 Heat shock 70 kDa protein 1A OS=Homo sapiens OX=9606 GN=HSPA1A PE=1 SV=1 3.88 2533.4 - 1.27E+07 - - - -1.459 - 1.393 0.267 - 112.6 1 2 0 -0.0018 13 0 0 0 - - - - - 1.8632 0.9998 221125_WJC_METTL3_EV_vs_WT_F04.13301.13301.2 0.344 14-Nov K.TEDLFENR[166.11].L "sp|Q92615|LAR4B_HUMAN,tr|H0Y641|H0Y641_HUMAN,tr|H0Y4V9|H0Y4V9_HUMAN" 3 1032.4752 1.51 47442 13301 2 1032.473892 517.2449 La-related protein 4B OS=Homo sapiens OX=9606 GN=LARP4B PE=1 SV=3 4.14 2533.5 - 1.17E+06 - - - -1.2271 - 2.295 0.38 - 696.5 1 2 0 -0.0013 8 0 0 0 6.09E+07 4.04E+07 - - - 4.3527 1 221125_WJC_METTL3_EV_vs_WT_F04.13302.13302.3 2.48E-06 15/64 R.AIGGGLSSVGGGSSTIK.Y "sp|P48668|K2C6C_HUMAN,sp|P02538|K2C6A_HUMAN" 2 1446.7678 999 47443 13302 3 1446.767704 483.2632 "Keratin, type II cytoskeletal 6C OS=Homo sapiens OX=9606 GN=KRT6C PE=1 SV=3" 8.8 2533.6 - 1.39E+06 - - - -0.0816 - 2.755 0.467 - 259.1 1 2 0 -0.0001 17 0 0 0 1.59E+08 0.00E+00 - - - 6.3068 1 221125_WJC_METTL3_EV_vs_WT_F04.13303.13303.2 4.33E-08 13/26 R.FYEQMNGPVAGASR.Q "sp|P29692|EF1D_HUMAN,tr|E9PI39|E9PI39_HUMAN,tr|E9PMW7|E9PMW7_HUMAN,tr|E9PKK3|E9PKK3_HUMAN,tr|E9PQ49|E9PQ49_HUMAN,tr|A0A087X1X7|A0A087X1X7_HUMAN,tr|E9PL12|E9PL12_HUMAN,tr|E9PK72|E9PK72_HUMAN,tr|H0YCK7|H0YCK7_HUMAN,tr|E9PQZ1|E9PQZ1_HUMAN,tr|E9PK06|E9PK06_HUMAN,tr|E9PIZ1|E9PIZ1_HUMAN,tr|E9PN91|E9PN91_HUMAN,tr|E9PPR1|E9PPR1_HUMAN,tr|E9PRY8|E9PRY8_HUMAN,tr|E9PK01|E9PK01_HUMAN,tr|E9PL71|E9PL71_HUMAN" 17 1525.6984 1.23 47444 13303 2 1525.696194 763.8565 Elongation factor 1-delta OS=Homo sapiens OX=9606 GN=EEF1D PE=1 SV=5 6 2533.7 - 1.13E+06 - - - -1.421 - 2.681 0.677 - 613.9 1 2 0 -0.0022 14 0 0 0 6.21E+07 5.04E+07 - - - 6.5154 0.9996 221125_WJC_METTL3_EV_vs_WT_F04.13304.13304.2 8.83E-05 18-Nov K.SYSQSSNLFR.H sp|P17028|ZNF24_HUMAN 1 1187.5571 1.4 47445 13304 2 1187.55418 594.7858 Zinc finger protein 24 OS=Homo sapiens OX=9606 GN=ZNF24 PE=1 SV=4 8.46 2533.9 - 930758 - - - -2.4597 - 1.921 0.517 - 362.5 1 2 0 -0.0029 10 0 0 0 3.25E+07 2.33E+07 - - - 4.6809 0.9604 221125_WJC_METTL3_EV_vs_WT_F04.13305.13305.3 0.00721 Sep-40 R.VR[166.11]VTELEDEVR[166.11].N "sp|Q9BV38|WDR18_HUMAN,tr|U3KQC1|U3KQC1_HUMAN,tr|A0A0A0MQU0|A0A0A0MQU0_HUMAN,tr|K7EIR0|K7EIR0_HUMAN" 4 1363.721 16.83 47446 13305 3 1363.721577 455.581 WD repeat-containing protein 18 OS=Homo sapiens OX=9606 GN=WDR18 PE=1 SV=2 4.41 2533.9 - 800478 - - - 0.3982 - 1.884 0.138 - 141 1 2 1 0.0005 11 0 0 0 9.44E+07 5.61E+06 - - - 1.8778 0.8673 221125_WJC_METTL3_EV_vs_WT_F04.13309.13309.3 1.38 Aug-36 R.QLSILVHPDK[136.11].N sp|O75937|DNJC8_HUMAN 1 1156.6696 0.52 47450 13309 3 1156.667323 386.5638 DnaJ homolog subfamily C member 8 OS=Homo sapiens OX=9606 GN=DNAJC8 PE=1 SV=2 6.74 2534.5 - 551714 - - - -1.9331 - 1.19 0.149 - 58.4 2 2 0 -0.0022 10 0 0 0 3.26E+06 6.26E+06 - - - 0.5693 0.9999 221125_WJC_METTL3_EV_vs_WT_F04.13310.13310.3 0.000518 Dec-40 R.ITADGAHFELR[166.11].L "sp|Q8IWX8|CHERP_HUMAN,tr|J3QK89|J3QK89_HUMAN" 2 1238.6283 0.99 47451 13310 3 1238.62537 413.8834 Calcium homeostasis endoplasmic reticulum protein OS=Homo sapiens OX=9606 GN=CHERP PE=1 SV=3 5.32 2534.6 - 522040 - - - -2.3704 - 3.065 0.385 - 163.1 1 2 0 -0.0029 11 0 0 0 1.86E+07 1.87E+07 - - - 6.0134 0.9998 221125_WJC_METTL3_EV_vs_WT_F04.13315.13315.2 0.00203 19/24 K.IAAEIAQAEEQAR[166.11].K "sp|Q969G3|SMCE1_HUMAN,tr|A0A2R8Y855|A0A2R8Y855_HUMAN,tr|A0A2R8YES3|A0A2R8YES3_HUMAN,tr|A0A2U3TZQ7|A0A2U3TZQ7_HUMAN,tr|A0A2R8Y7U4|A0A2R8Y7U4_HUMAN,tr|B4DGM3|B4DGM3_HUMAN,tr|J3QKS7|J3QKS7_HUMAN,tr|A0A2R8Y4T4|A0A2R8Y4T4_HUMAN,tr|A0A2R8Y7I9|A0A2R8Y7I9_HUMAN,tr|A0A2R8Y765|A0A2R8Y765_HUMAN" 10 1408.7186 1.9 47454 13315 2 1408.71639 705.3666 SWI\SNF-related matrix-associated actin-dependent regulator of chromatin subfamily E member 1 OS=Homo sapiens OX=9606 GN=SMARCE1 PE=1 SV=2 4.25 2535.1 - 837630 - - - -1.5525 - 2.947 0.358 - 1657.2 1 2 0 -0.0022 13 0 0 0 6.88E+07 3.63E+07 - - - 4.4584 0.9788 221125_WJC_METTL3_EV_vs_WT_F04.13317.13317.3 0.147 Dec-40 R.ELLTLDEKDPR.R "sp|P46781|RS9_HUMAN,tr|C9JM19|C9JM19_HUMAN,tr|B5MCT8|B5MCT8_HUMAN,tr|F2Z3C0|F2Z3C0_HUMAN,tr|A8MXK4|A8MXK4_HUMAN" 5 1327.6983 1.1 47456 13317 3 1327.696121 443.5734 40S ribosomal protein S9 OS=Homo sapiens OX=9606 GN=RPS9 PE=1 SV=3 4.32 2535.3 - 1.81E+06 - - - -1.6758 - 1.466 0.259 - 109.6 1 2 1 -0.0022 11 0 0 0 3.24E+08 2.95E+08 - - - 2.5137 0.9988 221125_WJC_METTL3_EV_vs_WT_F04.13319.13319.2 0.429 14-Jul R.FQLEELR[166.11]K[136.11].F "sp|Q8WWM7|ATX2L_HUMAN,tr|H3BUF6|H3BUF6_HUMAN" 2 1079.6094 1.52 47458 13319 2 1079.608416 540.812 Ataxin-2-like protein OS=Homo sapiens OX=9606 GN=ATXN2L PE=1 SV=2 6.14 2535.5 - 1.19E+06 - - - -0.9253 - 1.498 0.279 - 147 1 2 0 -0.001 8 0 0 0 1.85E+07 1.22E+07 - - - 2.3202 0.992 221125_WJC_METTL3_EV_vs_WT_F04.13320.13320.3 0.0473 Sep-36 R.EAYDR[166.11]DFLAR[166.11].V sp|P26572|MGAT1_HUMAN 1 1274.6158 1.45 47459 13320 3 1274.613822 425.8792 "Alpha-1,3-mannosyl-glycoprotein 2-beta-N-acetylglucosaminyltransferase OS=Homo sapiens OX=9606 GN=MGAT1 PE=1 SV=2" 4.56 2535.5 - 6.23E+06 - - - -1.5832 - 1.362 0.331 - 104.4 1 2 1 -0.002 10 0 0 0 1.86E+07 1.28E+07 - - - 3.132 0.9505 221125_WJC_METTL3_EV_vs_WT_F04.13321.13321.3 0.317 13/52 R.VAVEEVDEEGKFVR.L "sp|P02545|LMNA_HUMAN,tr|A0A804HL68|A0A804HL68_HUMAN,tr|Q5TCI8|Q5TCI8_HUMAN,tr|A0A6Q8PFJ0|A0A6Q8PFJ0_HUMAN,tr|A0A6Q8PHQ9|A0A6Q8PHQ9_HUMAN" 5 1604.8046 2.03 47460 13321 3 1604.804594 535.9421 Prelamin-A\C OS=Homo sapiens OX=9606 GN=LMNA PE=1 SV=1 4.25 2535.7 - 1.00E+06 - - - -0.005 - 1.768 0.151 - 155.9 1 2 1 0 14 0 0 0 1.87E+07 9.24E+06 - - - 1.7379 0.9996 221125_WJC_METTL3_EV_vs_WT_F04.13322.13322.2 0.000215 16-Aug K.VTLDWAKPK.G "sp|P19338|NUCL_HUMAN,tr|A0A7I2V699|A0A7I2V699_HUMAN,tr|A0A7I2V3F3|A0A7I2V3F3_HUMAN,tr|A0A7I2V428|A0A7I2V428_HUMAN,tr|H7BY16|H7BY16_HUMAN,tr|C9JLB1|C9JLB1_HUMAN" 6 1056.5968 0.73 47461 13322 2 1056.594481 529.3057 Nucleolin OS=Homo sapiens OX=9606 GN=NCL PE=1 SV=3 8.56 2535.8 - 786982 - - - -2.1768 - 2.022 0.429 - 173 1 2 0 -0.0023 9 0 0 0 8.49E+06 1.16E+07 - - - 4.2458 0.9874 221125_WJC_METTL3_EV_vs_WT_F04.13323.13323.2 0.000473 16-Oct L.TNEGIQYLR.D "sp|P46783|RS10_HUMAN,tr|A0A2R8Y6L3|A0A2R8Y6L3_HUMAN,tr|F6U211|F6U211_HUMAN,tr|A0A1W2PQS6|A0A1W2PQS6_HUMAN,tr|A0A2R8YFH6|A0A2R8YFH6_HUMAN,tr|A0A2R8Y7H1|A0A2R8Y7H1_HUMAN,tr|S4R435|S4R435_HUMAN" 7 1092.5564 0.93 47462 13323 2 1092.555273 547.2855 40S ribosomal protein S10 OS=Homo sapiens OX=9606 GN=RPS10 PE=1 SV=1 5.66 2535.9 - 762878 - - - -1.0068 - 2.098 0.415 - 379.7 1 1 0 -0.0011 9 0 0 0 1.51E+07 1.63E+07 - - - 4.2496 0.9998 221125_WJC_METTL3_EV_vs_WT_F04.13324.13324.2 0.000234 20-Oct R.EEIQDSLVGQR.Y "sp|Q7KZI7|MARK2_HUMAN,tr|A0A0A0MRU9|A0A0A0MRU9_HUMAN,tr|E7ETY4|E7ETY4_HUMAN,tr|A0A7I2YQR3|A0A7I2YQR3_HUMAN,tr|E9PC69|E9PC69_HUMAN,tr|A0A7I2V3R3|A0A7I2V3R3_HUMAN" 6 1272.631 0.89 47463 13324 2 1272.631128 637.3228 Serine\threonine-protein kinase MARK2 OS=Homo sapiens OX=9606 GN=MARK2 PE=1 SV=2 4.14 2536 - 3.62E+06 - - - 0.1053 - 1.974 0.425 - 204.9 1 2 0 0.0001 11 0 0 0 1.81E+07 2.04E+07 - - - 4.0197 0.8819 221125_WJC_METTL3_EV_vs_WT_F04.13326.13326.2 2.83E-05 14/22 K.EVDEQMLNVQNK[136.11].N "sp|Q9BVA1|TBB2B_HUMAN,sp|P07437|TBB5_HUMAN,sp|Q13885|TBB2A_HUMAN,sp|P68371|TBB4B_HUMAN,tr|Q5ST81|Q5ST81_HUMAN,tr|Q5JP53|Q5JP53_HUMAN" 6 1453.6962 0.35 47465 13326 2 1454.691501 727.8554 Tubulin beta-2B chain OS=Homo sapiens OX=9606 GN=TUBB2B PE=1 SV=1 4.14 2536.3 - 613082 - - - 684.6389 - 2.327 0.545 - 625.7 1 2 0 0.9953 12 0 0 0 2.85E+07 8.16E+07 - - - 4.9761 0.9998 221125_WJC_METTL3_EV_vs_WT_F04.13327.13327.3 0.00442 15/36 K.TVDLKPDWGK.G "sp|P31948|STIP1_HUMAN,tr|F5GXD8|F5GXD8_HUMAN,tr|F5H783|F5H783_HUMAN" 3 1157.6081 1.35 47466 13327 3 1157.608171 386.8766 Stress-induced-phosphoprotein 1 OS=Homo sapiens OX=9606 GN=STIP1 PE=1 SV=1 5.63 2536.4 - 493711 - - - 0.0838 - 2.172 0.348 - 300.5 1 2 0 0.0001 10 0 0 0 1.52E+07 1.13E+07 - - - 4.6851 0.9999 221125_WJC_METTL3_EV_vs_WT_F04.13335.13335.3 0.000124 14/48 K.IAAEIAQAEEQAR.K "sp|Q969G3|SMCE1_HUMAN,tr|A0A2R8Y855|A0A2R8Y855_HUMAN,tr|A0A2R8YES3|A0A2R8YES3_HUMAN,tr|A0A2U3TZQ7|A0A2U3TZQ7_HUMAN,tr|A0A2R8Y7U4|A0A2R8Y7U4_HUMAN,tr|B4DGM3|B4DGM3_HUMAN,tr|J3QKS7|J3QKS7_HUMAN,tr|A0A2R8Y4T4|A0A2R8Y4T4_HUMAN,tr|A0A2R8Y7I9|A0A2R8Y7I9_HUMAN,tr|A0A2R8Y765|A0A2R8Y765_HUMAN" 10 1398.7103 14.82 47472 13335 3 1398.707839 467.244 SWI\SNF-related matrix-associated actin-dependent regulator of chromatin subfamily E member 1 OS=Homo sapiens OX=9606 GN=SMARCE1 PE=1 SV=2 4.25 2537.1 - 732620 - - - -1.7645 - 2.724 0.375 - 498.9 1 2 0 -0.0025 13 0 0 0 1.60E+07 1.08E+06 - - - 5.4372 0.9996 221125_WJC_METTL3_EV_vs_WT_F04.13338.13338.2 0.000658 20-Nov R.EEIQDSLVGQR[166.11].Y "sp|Q7KZI7|MARK2_HUMAN,tr|A0A0A0MRU9|A0A0A0MRU9_HUMAN,tr|E7ETY4|E7ETY4_HUMAN,tr|A0A7I2YQR3|A0A7I2YQR3_HUMAN,tr|E9PC69|E9PC69_HUMAN,tr|A0A7I2V3R3|A0A7I2V3R3_HUMAN" 6 1282.6393 0.89 47473 13338 2 1282.635575 642.3269 Serine\threonine-protein kinase MARK2 OS=Homo sapiens OX=9606 GN=MARK2 PE=1 SV=2 4.14 2537.5 - 857454 - - - -2.8761 - 2.361 0.519 - 670 1 2 0 -0.0037 11 0 0 0 1.76E+07 1.98E+07 - - - 5.1972 0.9916 221125_WJC_METTL3_EV_vs_WT_F04.13340.13340.2 0.000823 20-Nov R.ELLTLDEK[136.11]DPR[166.11].R "sp|P46781|RS9_HUMAN,tr|C9JM19|C9JM19_HUMAN,tr|B5MCT8|B5MCT8_HUMAN,tr|F2Z3C0|F2Z3C0_HUMAN,tr|A8MXK4|A8MXK4_HUMAN" 5 1345.7208 0.96 47475 13340 2 1345.723586 673.8677 40S ribosomal protein S9 OS=Homo sapiens OX=9606 GN=RPS9 PE=1 SV=3 4.32 2537.8 - 1.02E+06 - - - 2.0584 - 1.929 0.366 - 251.3 1 2 1 0.0028 11 0 0 0 3.84E+07 4.00E+07 - - - 3.5208 0.9186 221125_WJC_METTL3_EV_vs_WT_F04.13341.13341.2 0.0137 14-Aug E.GFVDALHR.V "sp|Q96I24|FUBP3_HUMAN,tr|A0A494C1K6|A0A494C1K6_HUMAN" 2 913.477 1.71 47476 13341 2 913.474293 457.7458 Far upstream element-binding protein 3 OS=Homo sapiens OX=9606 GN=FUBP3 PE=1 SV=2 6.74 2537.9 - 729082 - - - -2.9634 - 1.587 0.407 - 291.4 1 1 0 -0.0027 8 0 0 0 1.44E+08 8.42E+07 - - - 3.4392 1 221125_WJC_METTL3_EV_vs_WT_F04.13345.13345.2 2.25E-07 13/22 K.EVDEQMLNVQNK[136.11].N "sp|Q9BVA1|TBB2B_HUMAN,sp|P07437|TBB5_HUMAN,sp|Q13885|TBB2A_HUMAN,sp|P68371|TBB4B_HUMAN,tr|Q5ST81|Q5ST81_HUMAN,tr|Q5JP53|Q5JP53_HUMAN" 6 1453.6962 0.35 47478 13345 2 1453.692379 727.8554 Tubulin beta-2B chain OS=Homo sapiens OX=9606 GN=TUBB2B PE=1 SV=1 4.14 2538.4 - 3.15E+06 - - - -2.6587 - 2.58 0.591 - 535.9 1 2 0 -0.0039 12 0 0 0 2.85E+07 8.16E+07 - - - 5.8987 0.9921 221125_WJC_METTL3_EV_vs_WT_F04.13347.13347.2 0.000677 18-Oct K.TSLMNQYVNK.K "sp|P51149|RAB7A_HUMAN,tr|C9J592|C9J592_HUMAN,tr|C9J4V0|C9J4V0_HUMAN,tr|C9J7D1|C9J7D1_HUMAN,tr|A0A6Q8PH84|A0A6Q8PH84_HUMAN,tr|C9J8S3|C9J8S3_HUMAN,tr|C9IZZ0|C9IZZ0_HUMAN,tr|C9J4S4|C9J4S4_HUMAN,tr|A0A6Q8PG52|A0A6Q8PG52_HUMAN" 9 1196.586 13.4 47480 13347 2 1196.583427 599.3003 Ras-related protein Rab-7a OS=Homo sapiens OX=9606 GN=RAB7A PE=1 SV=1 8.26 2538.6 - 1.77E+06 - - - -2.1152 - 1.753 0.105 - 324.7 1 2 0 -0.0025 10 0 0 0 2.20E+07 1.64E+06 - - - 1.3826 0.9999 221125_WJC_METTL3_EV_vs_WT_F04.13348.13348.3 1.35E-05 Dec-36 K.DNALVELDHR.L "sp|Q8NEL9|DDHD1_HUMAN,tr|A0A087X0H7|A0A087X0H7_HUMAN" 2 1180.5837 0.81 47481 13348 3 1180.584127 394.5352 Phospholipase DDHD1 OS=Homo sapiens OX=9606 GN=DDHD1 PE=1 SV=2 4.54 2538.7 - 425102 - - - 0.404 - 2.086 0.405 - 197.2 1 2 0 0.0005 10 0 0 0 5.63E+06 7.00E+06 - - - 5.2025 0.9909 221125_WJC_METTL3_EV_vs_WT_F04.13351.13351.2 0.0001 14/20 R.ELLTLDEKDPR.R "sp|P46781|RS9_HUMAN,tr|C9JM19|C9JM19_HUMAN,tr|B5MCT8|B5MCT8_HUMAN,tr|F2Z3C0|F2Z3C0_HUMAN,tr|A8MXK4|A8MXK4_HUMAN" 5 1327.6983 0.96 47482 13351 2 1327.694252 664.8564 40S ribosomal protein S9 OS=Homo sapiens OX=9606 GN=RPS9 PE=1 SV=3 4.32 2539.1 - 2.32E+06 - - - -3.0835 - 2.357 0.397 - 382.9 1 2 1 -0.0041 11 0 0 0 3.84E+07 4.00E+07 - - - 4.2914 0.9999 221125_WJC_METTL3_EV_vs_WT_F04.13353.13353.2 5.65E-06 22-Dec K.QGEEEDAEIIVK[136.11].L "sp|Q9UHX1|PUF60_HUMAN,tr|A0A0J9YYL3|A0A0J9YYL3_HUMAN,tr|A0A0J9YXX5|A0A0J9YXX5_HUMAN,tr|A0A0J9YXJ8|A0A0J9YXJ8_HUMAN,tr|A0A0J9YVP6|A0A0J9YVP6_HUMAN" 5 1366.6707 2.14 47484 13353 2 1366.668817 684.3426 Poly(U)-binding-splicing factor PUF60 OS=Homo sapiens OX=9606 GN=PUF60 PE=1 SV=1 3.91 2539.4 - 1.48E+06 - - - -1.4071 - 2.415 0.546 - 646.2 1 2 0 -0.0019 12 0 0 0 6.57E+07 3.07E+07 - - - 5.3931 0.9968 221125_WJC_METTL3_EV_vs_WT_F04.13356.13356.3 0.0818 15/36 R.R[166.11]K[136.11]PFYPALIR[166.11].Y "sp|O00746|NDKM_HUMAN,tr|Q4TT34|Q4TT34_HUMAN,tr|H0Y6J0|H0Y6J0_HUMAN,tr|F2Z2X0|F2Z2X0_HUMAN,tr|A2IDC9|A2IDC9_HUMAN" 5 1287.781 2.01 47487 13356 3 1287.778205 430.2676 "Nucleoside diphosphate kinase, mitochondrial OS=Homo sapiens OX=9606 GN=NME4 PE=1 SV=1" 11 2539.8 - 1.10E+06 - - - -2.172 - 2.017 0.215 - 340.8 1 2 0 -0.0028 10 0 0 0 7.33E+07 3.65E+07 - - - 2.9853 0.9805 221125_WJC_METTL3_EV_vs_WT_F04.13357.13357.2 0.00801 14-Sep E.GFVDALHR[166.11].V "sp|Q96I24|FUBP3_HUMAN,tr|A0A494C1K6|A0A494C1K6_HUMAN" 2 923.4853 1.71 47488 13357 2 923.485655 462.7499 Far upstream element-binding protein 3 OS=Homo sapiens OX=9606 GN=FUBP3 PE=1 SV=2 6.74 2539.9 - 1.05E+06 - - - 0.4169 - 1.858 0.356 - 381.4 1 1 0 0.0004 8 0 0 0 1.44E+08 8.42E+07 - - - 3.5387 0.9983 221125_WJC_METTL3_EV_vs_WT_F04.13359.13359.2 1.11E-05 24-Dec R.AYQHGGVTGLSQY.- sp|Q92900|RENT1_HUMAN 1 1379.647 - 47490 13359 2 1379.640148 690.8308 Regulator of nonsense transcripts 1 OS=Homo sapiens OX=9606 GN=UPF1 PE=1 SV=2 6.78 2540.2 - 696983 - - - -4.9513 - 2.319 0.577 - 445.4 1 2 0 -0.0068 13 0 0 0 - - - - - 5.4594 0.9933 221125_WJC_METTL3_EV_vs_WT_F04.13366.13366.2 4.97E-06 16-Nov A.EGFVDALHR.V "sp|Q96I24|FUBP3_HUMAN,tr|A0A494C1K6|A0A494C1K6_HUMAN" 2 1042.5196 1.55 47495 13366 2 1042.519235 522.2671 Far upstream element-binding protein 3 OS=Homo sapiens OX=9606 GN=FUBP3 PE=1 SV=2 5.32 2541 - 1.81E+06 - - - -0.3434 - 2.191 0.498 - 450.7 1 1 0 -0.0004 9 0 0 0 6.61E+07 4.25E+07 - - - 4.9883 0.9995 221125_WJC_METTL3_EV_vs_WT_F04.13368.13368.2 1.37E-05 18-Nov K.AEGFVDALHR[166.11].V "sp|Q96I24|FUBP3_HUMAN,tr|A0A494C1K6|A0A494C1K6_HUMAN" 2 1123.565 2.6 47497 13368 2 1123.561487 562.7898 Far upstream element-binding protein 3 OS=Homo sapiens OX=9606 GN=FUBP3 PE=1 SV=2 5.32 2541.1 - 9.41E+06 - - - -3.1062 - 2.301 0.489 - 713.6 1 2 0 -0.0035 10 0 0 0 4.78E+08 1.84E+08 - - - 4.9778 0.9991 221125_WJC_METTL3_EV_vs_WT_F04.13370.13370.3 0.264 Sep-40 R.TYGLPC[160.03]HC[160.03]PFK.E "sp|P17900|SAP3_HUMAN,tr|H0YBY3|H0YBY3_HUMAN" 2 1378.6162 12.16 47499 13370 3 1378.613213 460.546 Ganglioside GM2 activator OS=Homo sapiens OX=9606 GN=GM2A PE=1 SV=4 7.76 2541.3 - 615174 - - - -2.1761 - 1.687 0.353 - 111.1 1 2 0 -0.003 11 0 0 0 1.65E+07 1.36E+06 - - - 3.9604 0.9998 221125_WJC_METTL3_EV_vs_WT_F04.13371.13371.2 5.58E-06 14/26 K.QAGGFLGPPPPSGK.F "sp|Q9UM00|TMCO1_HUMAN,tr|J3QQY2|J3QQY2_HUMAN" 2 1308.6826 0.79 47500 13371 2 1308.680838 655.3486 Calcium load-activated calcium channel OS=Homo sapiens OX=9606 GN=TMCO1 PE=1 SV=2 8.75 2541.5 - 540735 - - - -1.3739 - 2.257 0.484 - 592.4 1 2 0 -0.0018 14 0 0 0 6.91E+06 8.75E+06 - - - 4.658 0.9816 221125_WJC_METTL3_EV_vs_WT_F04.13376.13376.2 1.93E-06 16-Dec A.EGFVDALHR[166.11].V "sp|Q96I24|FUBP3_HUMAN,tr|A0A494C1K6|A0A494C1K6_HUMAN" 2 1052.5279 1.77 47503 13376 2 1052.525505 527.2712 Far upstream element-binding protein 3 OS=Homo sapiens OX=9606 GN=FUBP3 PE=1 SV=2 5.32 2542.1 - 2.11E+06 - - - -2.2403 - 2.208 0.475 - 542.4 1 1 0 -0.0024 9 0 0 0 6.58E+07 3.71E+07 - - - 4.8402 0.9985 221125_WJC_METTL3_EV_vs_WT_F04.13377.13377.2 8.04E-05 20-Oct K.TSTPTTDLPIK.V "sp|Q9UPW6|SATB2_HUMAN,tr|C9JR56|C9JR56_HUMAN" 2 1172.6289 2.39 47504 13377 2 1172.624141 587.3217 DNA-binding protein SATB2 OS=Homo sapiens OX=9606 GN=SATB2 PE=1 SV=2 5.5 2542.3 - 1.07E+06 - - - -4.032 - 2.028 0.468 - 430.1 1 2 0 -0.0047 11 0 0 0 2.09E+07 8.78E+06 - - - 4.4089 0.9999 221125_WJC_METTL3_EV_vs_WT_F04.13378.13378.3 3.63E-06 17/44 R.RMPPPANLPSLK.A "sp|P48634|PRC2A_HUMAN,sp|Q5JSZ5|PRC2B_HUMAN,sp|Q9Y520|PRC2C_HUMAN,tr|E7EPN9|E7EPN9_HUMAN" 4 1319.7384 1.18 47505 13378 3 1319.735349 440.9201 Protein PRRC2A OS=Homo sapiens OX=9606 GN=PRRC2A PE=1 SV=3 11 2542.4 - 631577 - - - -2.2944 - 3.058 0.462 - 485.6 1 2 0 -0.003 12 0 0 0 2.24E+07 1.90E+07 - - - 6.7883 0.9999 221125_WJC_METTL3_EV_vs_WT_F04.13381.13381.3 4.15E-08 17/48 K.IIGHFYASQMAQR.K sp|Q9NZI8|IF2B1_HUMAN 1 1520.7558 1.47 47506 13381 3 1520.751553 507.9259 Insulin-like growth factor 2 mRNA-binding protein 1 OS=Homo sapiens OX=9606 GN=IGF2BP1 PE=1 SV=2 8.75 2542.8 - 1.97E+06 - - - -2.8045 - 3.229 0.492 - 524.1 1 2 0 -0.0043 13 0 0 0 1.70E+08 1.15E+08 - - - 7.2022 0.9999 221125_WJC_METTL3_EV_vs_WT_F04.13382.13382.3 9.24E-05 15/48 K.IIGHFYASQMAQR[166.11].K sp|Q9NZI8|IF2B1_HUMAN 1 1530.7641 1.48 47507 13382 3 1530.764234 511.262 Insulin-like growth factor 2 mRNA-binding protein 1 OS=Homo sapiens OX=9606 GN=IGF2BP1 PE=1 SV=2 8.75 2542.8 - 1.16E+06 - - - 0.0954 - 2.298 0.397 - 315.8 1 2 0 0.0001 13 0 0 0 1.71E+08 1.16E+08 - - - 5.222 0.9276 221125_WJC_METTL3_EV_vs_WT_F04.13386.13386.2 0.0208 16-Oct K.DKLSELQLR.V sp|Q9BVK6|TMED9_HUMAN 1 1100.619 1.28 47511 13386 2 1100.616214 551.3168 Transmembrane emp24 domain-containing protein 9 OS=Homo sapiens OX=9606 GN=TMED9 PE=1 SV=2 6.07 2543.2 - 1.16E+06 - - - -2.5068 - 1.854 0.119 - 357.4 1 2 1 -0.0028 9 0 0 0 3.27E+07 2.55E+07 - - - 1.7051 0.9998 221125_WJC_METTL3_EV_vs_WT_F04.13387.13387.2 0.000533 18-Sep K.ESNTDQGFFK.E sp|Q9HC52|CBX8_HUMAN 1 1171.5146 2.01 47512 13387 2 1171.515418 586.7646 Chromobox protein homolog 8 OS=Homo sapiens OX=9606 GN=CBX8 PE=1 SV=3 4.37 2543.3 - 976584 - - - 0.7256 - 1.885 0.503 - 368.3 1 2 0 0.0009 10 0 0 0 2.21E+07 1.10E+07 - - - 4.5254 0.9977 221125_WJC_METTL3_EV_vs_WT_F04.13388.13388.2 3.56E-05 14/24 K.QTEVLLQPNPNAR.L "sp|Q9Y371|SHLB1_HUMAN,tr|A0A087WW40|A0A087WW40_HUMAN" 2 1478.7841 1.86 47513 13388 2 1478.776241 740.3993 Endophilin-B1 OS=Homo sapiens OX=9606 GN=SH3GLB1 PE=1 SV=1 6 2543.4 - 822600 - - - -5.3422 - 2.895 0.487 - 542.1 1 2 0 -0.0079 13 0 0 0 2.76E+07 1.48E+07 - - - 5.3637 0.9857 221125_WJC_METTL3_EV_vs_WT_F04.13389.13389.2 0.00782 20-Dec K.NLSEALGDNVK[136.11].Q sp|Q96BN2|TADA1_HUMAN 1 1166.6023 1.88 47514 13389 2 1166.595813 584.3084 Transcriptional adapter 1 OS=Homo sapiens OX=9606 GN=TADA1 PE=1 SV=1 4.37 2543.6 - 705634 - - - -5.5323 - 1.915 0.297 - 407.8 1 2 0 -0.0065 11 0 0 0 1.21E+07 6.45E+06 - - - 2.9903 0.9995 221125_WJC_METTL3_EV_vs_WT_F04.13392.13392.2 0.000572 16-Nov K.SPLQSVVVR.R "sp|Q9Y2W1|TR150_HUMAN,tr|A0A3B3ITZ9|A0A3B3ITZ9_HUMAN" 2 983.5764 2.41 47515 13392 2 983.574471 492.7955 Thyroid hormone receptor-associated protein 3 OS=Homo sapiens OX=9606 GN=THRAP3 PE=1 SV=2 9.47 2543.9 - 3.36E+06 - - - -1.9409 - 2.259 0.348 - 430 1 2 0 -0.0019 9 0 0 0 7.47E+07 3.10E+07 - - - 3.9683 0.9916 221125_WJC_METTL3_EV_vs_WT_F04.13393.13393.3 0.000413 13/36 K.EDLYLK[136.11]PIQR[166.11].T sp|P13639|EF2_HUMAN 1 1291.7255 0.69 47516 13393 3 1291.721157 431.5824 Elongation factor 2 OS=Homo sapiens OX=9606 GN=EEF2 PE=1 SV=4 6.17 2544.1 - 1.53E+06 - - - -3.3676 - 2.367 0.168 - 264.2 1 2 0 -0.0043 10 0 0 0 7.00E+07 1.02E+08 - - - 2.9281 0.9999 221125_WJC_METTL3_EV_vs_WT_F04.13394.13394.3 0.000848 20/60 R.VFDK[136.11]EGNGTVMGAELR[166.11].H "sp|P08590|MYL3_HUMAN,sp|P05976|MYL1_HUMAN,sp|P60660|MYL6_HUMAN,tr|F8W1R7|F8W1R7_HUMAN,tr|G3V1V0|G3V1V0_HUMAN,tr|B7Z6Z4|B7Z6Z4_HUMAN,tr|F8VZU9|F8VZU9_HUMAN,tr|G8JLA2|G8JLA2_HUMAN,tr|H0YI43|H0YI43_HUMAN,tr|F8W180|F8W180_HUMAN,tr|G3V1Y7|G3V1Y7_HUMAN,tr|J3KND3|J3KND3_HUMAN,tr|F8VPF3|F8VPF3_HUMAN" 13 1739.8631 1.23 47517 13394 3 1739.86264 580.9617 Myosin light chain 3 OS=Homo sapiens OX=9606 GN=MYL3 PE=1 SV=3 4.68 2544.2 - 1.95E+06 - - - -0.2874 - 3.101 0.478 - 435.2 1 2 1 -0.0005 16 0 0 0 8.79E+07 7.13E+07 - - - 6.7729 0.9993 221125_WJC_METTL3_EV_vs_WT_F04.13396.13396.3 2.30E-07 17/60 R.VFDKEGNGTVMGAELR.H "sp|P08590|MYL3_HUMAN,sp|P05976|MYL1_HUMAN,sp|P60660|MYL6_HUMAN,tr|F8W1R7|F8W1R7_HUMAN,tr|G3V1V0|G3V1V0_HUMAN,tr|B7Z6Z4|B7Z6Z4_HUMAN,tr|F8VZU9|F8VZU9_HUMAN,tr|G8JLA2|G8JLA2_HUMAN,tr|H0YI43|H0YI43_HUMAN,tr|F8W180|F8W180_HUMAN,tr|G3V1Y7|G3V1Y7_HUMAN,tr|J3KND3|J3KND3_HUMAN,tr|F8VPF3|F8VPF3_HUMAN" 13 1721.8407 1.23 47519 13396 3 1721.833789 574.9542 Myosin light chain 3 OS=Homo sapiens OX=9606 GN=MYL3 PE=1 SV=3 4.68 2544.4 - 1.29E+06 - - - -3.9963 - 3.001 0.512 - 283.1 1 2 1 -0.0069 16 0 0 0 8.79E+07 7.13E+07 - - - 7.0661 0.9671 221125_WJC_METTL3_EV_vs_WT_F04.13399.13399.2 1.47E-07 22-Nov L.INYQDDAELATR.A "sp|P35222|CTNB1_HUMAN,sp|P14923|PLAK_HUMAN,tr|C9JKY1|C9JKY1_HUMAN,tr|A0A2R8Y5C3|A0A2R8Y5C3_HUMAN,tr|C9JK18|C9JK18_HUMAN,tr|A0A2R8YCH5|A0A2R8YCH5_HUMAN,tr|A0A2R8Y543|A0A2R8Y543_HUMAN,tr|A0A2R8Y750|A0A2R8Y750_HUMAN,tr|B4DGU4|B4DGU4_HUMAN,tr|C9JTX4|C9JTX4_HUMAN,tr|A0A2R8Y5A3|A0A2R8Y5A3_HUMAN,tr|A0A2R8Y804|A0A2R8Y804_HUMAN,tr|C9J826|C9J826_HUMAN,tr|A0A2R8Y5Z1|A0A2R8Y5Z1_HUMAN,tr|A0A2R8Y7Z0|A0A2R8Y7Z0_HUMAN" 15 1407.663 21.51 47520 13399 2 1407.665979 704.8388 Catenin beta-1 OS=Homo sapiens OX=9606 GN=CTNNB1 PE=1 SV=1 4.03 2544.8 - 710883 - - - 2.0999 - 2.61 0.317 - 451.4 1 1 0 0.003 12 0 0 0 1.29E+07 6.00E+05 - - - 3.9056 0.9445 221125_WJC_METTL3_EV_vs_WT_F04.13401.13401.2 0.0965 16-Sep K.DK[136.11]LSELQLR[166.11].V sp|Q9BVK6|TMED9_HUMAN 1 1118.6414 1.29 47522 13401 2 1118.639283 560.328 Transmembrane emp24 domain-containing protein 9 OS=Homo sapiens OX=9606 GN=TMED9 PE=1 SV=2 6.07 2545 - 1.57E+06 - - - -1.9309 - 2.024 0.071 - 384.8 1 2 1 -0.0022 9 0 0 0 3.35E+07 2.59E+07 - - - 1.6045 0.9998 221125_WJC_METTL3_EV_vs_WT_F04.13402.13402.2 0.00708 16-Oct K.WELDDSSEK.H sp|Q8WUM0|NU133_HUMAN 1 1107.472 1.99 47523 13402 2 1107.471911 554.7433 Nuclear pore complex protein Nup133 OS=Homo sapiens OX=9606 GN=NUP133 PE=1 SV=2 3.92 2545.2 - 1.22E+06 - - - -0.1111 - 1.971 0.381 - 426 1 2 0 -0.0001 9 0 0 0 1.63E+07 8.15E+06 - - - 3.8181 0.9989 221125_WJC_METTL3_EV_vs_WT_F04.13404.13404.2 7.13E-05 24-Oct R.TLTEPC[160.03]PLASESR.V "sp|Q969N2|PIGT_HUMAN,tr|A0A1W2PRZ8|A0A1W2PRZ8_HUMAN,tr|A0A1W2PP53|A0A1W2PP53_HUMAN,tr|H7C2Y2|H7C2Y2_HUMAN,tr|A0A1W2PPR6|A0A1W2PPR6_HUMAN,tr|A0A1W2PPS0|A0A1W2PPS0_HUMAN,tr|A0A1W2PR92|A0A1W2PR92_HUMAN,tr|A0A1W2PPI8|A0A1W2PPI8_HUMAN,tr|A0A1W2PQ52|A0A1W2PQ52_HUMAN,tr|A0A1W2PRH2|A0A1W2PRH2_HUMAN,tr|A0A1W2PNP0|A0A1W2PNP0_HUMAN,tr|A0A1W2PP57|A0A1W2PP57_HUMAN,tr|A0A1W2PPQ7|A0A1W2PPQ7_HUMAN,tr|A0A1W2PP13|A0A1W2PP13_HUMAN,tr|A0A1W2PQ29|A0A1W2PQ29_HUMAN,tr|A0A1W2PQN1|A0A1W2PQN1_HUMAN,tr|A0A1W2PPC3|A0A1W2PPC3_HUMAN" 17 1459.6977 6.23 47525 13404 2 1459.691978 730.8561 GPI transamidase component PIG-T OS=Homo sapiens OX=9606 GN=PIGT PE=1 SV=1 4.53 2545.4 - 593614 - - - -3.9159 - 2.099 0.515 - 236.5 1 2 0 -0.0057 13 0 0 0 1.38E+07 2.21E+06 - - - 4.746 0.9998 221125_WJC_METTL3_EV_vs_WT_F04.13405.13405.2 4.87E-08 26-Dec R.TVMVQEGNVESAYR[166.11].T sp|P82921|RT21_HUMAN 1 1591.754 1.65 47526 13405 2 1591.752154 796.8843 "28S ribosomal protein S21, mitochondrial OS=Homo sapiens OX=9606 GN=MRPS21 PE=1 SV=3" 4.53 2545.6 - 590508 - - - -1.1453 - 2.455 0.421 - 453.3 1 2 0 -0.0018 14 0 0 0 7.52E+06 4.56E+06 - - - 4.4037 0.9999 221125_WJC_METTL3_EV_vs_WT_F04.13407.13407.2 0.000184 15/24 K.IIGHFYASQMAQR.K sp|Q9NZI8|IF2B1_HUMAN 1 1520.7558 1.4 47528 13407 2 1520.754286 761.3852 Insulin-like growth factor 2 mRNA-binding protein 1 OS=Homo sapiens OX=9606 GN=IGF2BP1 PE=1 SV=2 8.75 2545.8 - 470663 - - - -1.0074 - 2.508 0.56 - 762.1 1 2 0 -0.0015 13 0 0 0 1.63E+07 1.17E+07 - - - 5.5366 0.9998 221125_WJC_METTL3_EV_vs_WT_F04.13408.13408.2 5.04E-07 18-Sep K.DPNVVGQLAK[136.11].Q "sp|Q96I99|SUCB2_HUMAN,tr|E9PDQ8|E9PDQ8_HUMAN" 2 1047.5804 1.67 47529 13408 2 1047.580019 524.7975 "Succinate--CoA ligase [GDP-forming] subunit beta, mitochondrial OS=Homo sapiens OX=9606 GN=SUCLG2 PE=1 SV=2" 5.84 2545.9 - 345532 - - - -0.3723 - 1.948 0.476 - 212.1 1 2 0 -0.0004 10 0 0 0 1.10E+07 6.56E+06 - - - 4.4179 0.9998 221125_WJC_METTL3_EV_vs_WT_F04.13412.13412.3 0.000839 16/48 R.QIILEK[136.11]EETEELK[136.11].R "sp|P12956|XRCC6_HUMAN,tr|B1AHC9|B1AHC9_HUMAN" 2 1616.8844 1.24 47531 13412 3 1616.883423 539.9687 X-ray repair cross-complementing protein 6 OS=Homo sapiens OX=9606 GN=XRCC6 PE=1 SV=2 4.33 2546.5 - 1.15E+06 - - - -0.5851 - 2.671 0.431 - 381.7 1 2 1 -0.0009 13 0 0 0 2.02E+07 1.63E+07 - - - 6.0087 0.9997 221125_WJC_METTL3_EV_vs_WT_F04.13413.13413.3 0.00116 13/40 R.EIAQDFK[136.11]TDLR[166.11].F "sp|Q16695|H31T_HUMAN,sp|P84243|H33_HUMAN,sp|Q71DI3|H32_HUMAN,sp|P68431|H31_HUMAN,tr|B4DEB1|B4DEB1_HUMAN,tr|K7EK07|K7EK07_HUMAN,tr|K7ES00|K7ES00_HUMAN,tr|K7EMV3|K7EMV3_HUMAN,tr|A0A590UJJ6|A0A590UJJ6_HUMAN" 9 1352.7055 1.08 47532 13413 3 1352.703453 451.9091 Histone H3.1t OS=Homo sapiens OX=9606 GN=H3-4 PE=1 SV=3 4.56 2546.6 - 1.14E+06 - - - -1.5133 - 2.476 0.416 - 262.9 1 2 1 -0.002 11 0 0 0 3.39E+07 3.14E+07 - - - 5.753 1 221125_WJC_METTL3_EV_vs_WT_F04.13415.13415.2 4.96E-07 14/30 R.EPSVPASC[160.03]AVSATYER.S "sp|Q92615|LAR4B_HUMAN,tr|H0Y641|H0Y641_HUMAN,tr|H0Y4V9|H0Y4V9_HUMAN" 3 1722.7883 1.29 47534 13415 2 1722.785656 862.4014 La-related protein 4B OS=Homo sapiens OX=9606 GN=LARP4B PE=1 SV=3 4.53 2546.9 - 836154 - - - -1.5347 - 2.501 0.635 - 368.3 1 2 0 -0.0026 16 0 0 0 3.46E+07 2.67E+07 - - - 5.984 1 221125_WJC_METTL3_EV_vs_WT_F04.13416.13416.2 3.95E-10 15/30 R.EPSVPASC[160.03]AVSATYER[166.11].S "sp|Q92615|LAR4B_HUMAN,tr|H0Y641|H0Y641_HUMAN,tr|H0Y4V9|H0Y4V9_HUMAN" 3 1732.7966 1.27 47535 13416 2 1732.794773 867.4056 La-related protein 4B OS=Homo sapiens OX=9606 GN=LARP4B PE=1 SV=3 4.53 2547 - 724472 - - - -1.0371 - 2.638 0.713 - 414.2 1 2 0 -0.0018 16 0 0 0 3.21E+07 2.53E+07 - - - 6.6915 1 221125_WJC_METTL3_EV_vs_WT_F04.13417.13417.2 3.13E-08 14/24 K.IIGHFYASQMAQR[166.11].K sp|Q9NZI8|IF2B1_HUMAN 1 1530.7641 1.35 47536 13417 2 1530.764953 766.3893 Insulin-like growth factor 2 mRNA-binding protein 1 OS=Homo sapiens OX=9606 GN=IGF2BP1 PE=1 SV=2 8.75 2547.1 - 702520 - - - 0.5651 - 2.572 0.629 - 707.6 1 2 0 0.0009 13 0 0 0 1.57E+07 1.17E+07 - - - 6.1111 0.9989 221125_WJC_METTL3_EV_vs_WT_F04.13421.13421.2 2.39E-05 24-Dec R.TLTEPC[160.03]PLASESR[166.11].V "sp|Q969N2|PIGT_HUMAN,tr|A0A1W2PRZ8|A0A1W2PRZ8_HUMAN,tr|A0A1W2PP53|A0A1W2PP53_HUMAN,tr|H7C2Y2|H7C2Y2_HUMAN,tr|A0A1W2PPR6|A0A1W2PPR6_HUMAN,tr|A0A1W2PPS0|A0A1W2PPS0_HUMAN,tr|A0A1W2PR92|A0A1W2PR92_HUMAN,tr|A0A1W2PPI8|A0A1W2PPI8_HUMAN,tr|A0A1W2PQ52|A0A1W2PQ52_HUMAN,tr|A0A1W2PRH2|A0A1W2PRH2_HUMAN,tr|A0A1W2PNP0|A0A1W2PNP0_HUMAN,tr|A0A1W2PP57|A0A1W2PP57_HUMAN,tr|A0A1W2PPQ7|A0A1W2PPQ7_HUMAN,tr|A0A1W2PP13|A0A1W2PP13_HUMAN,tr|A0A1W2PQ29|A0A1W2PQ29_HUMAN,tr|A0A1W2PQN1|A0A1W2PQN1_HUMAN,tr|A0A1W2PPC3|A0A1W2PPC3_HUMAN" 17 1469.706 5.91 47540 13421 2 1469.701756 735.8603 GPI transamidase component PIG-T OS=Homo sapiens OX=9606 GN=PIGT PE=1 SV=1 4.53 2547.6 - 274818 - - - -2.8632 - 2.199 0.356 - 419.6 1 2 0 -0.0042 13 0 0 0 1.31E+07 2.21E+06 - - - 3.6915 0.9946 221125_WJC_METTL3_EV_vs_WT_F04.13424.13424.3 0.00116 13/36 K.EDLYLKPIQR.T sp|P13639|EF2_HUMAN 1 1273.703 0.66 47541 13424 3 1273.702782 425.575 Elongation factor 2 OS=Homo sapiens OX=9606 GN=EEF2 PE=1 SV=4 6.17 2548 - 4.20E+06 - - - -0.2002 - 1.959 0.151 - 252.2 1 2 0 -0.0003 10 0 0 0 6.72E+07 1.02E+08 - - - 2.1872 0.9999 221125_WJC_METTL3_EV_vs_WT_F04.13426.13426.3 3.83E-05 15/48 R.QIILEKEETEELK.R "sp|P12956|XRCC6_HUMAN,tr|B1AHC9|B1AHC9_HUMAN" 2 1600.856 1.24 47543 13426 3 1600.85584 534.6259 X-ray repair cross-complementing protein 6 OS=Homo sapiens OX=9606 GN=XRCC6 PE=1 SV=2 4.33 2548.2 - 2.44E+06 - - - -0.0806 - 3.018 0.508 - 384.7 1 2 1 -0.0001 13 0 0 0 2.02E+07 1.63E+07 - - - 7.1985 0.9997 221125_WJC_METTL3_EV_vs_WT_F04.13427.13427.2 3.04E-06 18-Sep K.EDLYLK[136.11]PIQR[166.11].T sp|P13639|EF2_HUMAN 1 1291.7255 0.39 47544 13427 2 1291.72621 646.87 Elongation factor 2 OS=Homo sapiens OX=9606 GN=EEF2 PE=1 SV=4 6.17 2548.3 - 1.17E+06 - - - 0.5442 - 1.79 0.434 - 361.9 1 2 0 0.0007 10 0 0 0 4.98E+06 1.27E+07 - - - 3.8714 1 221125_WJC_METTL3_EV_vs_WT_F04.13428.13428.3 0.000219 15/44 R.TFIAIK[136.11]PDGVQR[166.11].G "sp|P15531|NDKA_HUMAN,sp|P22392|NDKB_HUMAN,tr|Q32Q12|Q32Q12_HUMAN,tr|Q32Q12|Q32Q12_HUMAN,tr|J3KPD9|J3KPD9_HUMAN,tr|F6XY72|F6XY72_HUMAN,tr|E5RHP0|E5RHP0_HUMAN,tr|E7ERL0|E7ERL0_HUMAN,tr|C9K028|C9K028_HUMAN" 9 1361.7786 1.38 47545 13428 3 1361.777582 454.9335 Nucleoside diphosphate kinase A OS=Homo sapiens OX=9606 GN=NME1 PE=1 SV=1 8.41 2548.4 - 923173 - - - -0.7512 - 2.552 0.464 - 286.5 1 2 0 -0.001 12 0 0 0 2.21E+09 1.60E+09 - - - 6.3097 0.9999 221125_WJC_METTL3_EV_vs_WT_F04.13429.13429.3 0.00081 Nov-32 K.MRPFEGFQR.K "sp|Q9BUJ2|HNRL1_HUMAN,tr|A0A0A0MRA5|A0A0A0MRA5_HUMAN,tr|M0R3F1|M0R3F1_HUMAN,tr|B7Z4B8|B7Z4B8_HUMAN" 4 1166.5655 1.57 47546 13429 3 1166.5639 389.8624 Heterogeneous nuclear ribonucleoprotein U-like protein 1 OS=Homo sapiens OX=9606 GN=HNRNPUL1 PE=1 SV=2 9.35 2548.5 - 741675 - - - -1.3698 - 2.151 0.414 - 229.9 1 2 0 -0.0016 9 0 0 0 1.04E+08 6.65E+07 - - - 5.4636 0.8831 221125_WJC_METTL3_EV_vs_WT_F04.13430.13430.2 0.322 18-Aug K.TDGFGIDTC[160.03]R[166.11].S "sp|P04632|CPNS1_HUMAN,tr|A0A075B7C0|A0A075B7C0_HUMAN,tr|A0A0C4DGQ5|A0A0C4DGQ5_HUMAN,tr|K7ELJ7|K7ELJ7_HUMAN,tr|U3KPR7|U3KPR7_HUMAN,tr|U3KQE2|U3KQE2_HUMAN,tr|K7EIV0|K7EIV0_HUMAN,tr|K7EKD8|K7EKD8_HUMAN,tr|K7EM73|K7EM73_HUMAN" 9 1150.4952 1.96 47547 13430 2 1150.489062 576.2549 Calpain small subunit 1 OS=Homo sapiens OX=9606 GN=CAPNS1 PE=1 SV=1 4.21 2548.5 - 7.78E+06 - - - -5.3725 - 1.302 0.175 - 193.4 1 2 0 -0.0062 10 0 0 0 1.68E+07 8.60E+06 - - - 1.0682 0.8334 221125_WJC_METTL3_EV_vs_WT_F04.13431.13431.2 0.000392 18-Aug K.EDLYLKPIQR.T sp|P13639|EF2_HUMAN 1 1273.703 0.39 47548 13431 2 1273.696006 637.8588 Elongation factor 2 OS=Homo sapiens OX=9606 GN=EEF2 PE=1 SV=4 6.17 2548.7 - 658281 - - - -5.5201 - 1.613 0.083 - 258 2 2 0 -0.007 10 0 0 0 4.98E+06 1.27E+07 - - - 0.8519 0.9999 221125_WJC_METTL3_EV_vs_WT_F04.13432.13432.2 0.00489 14/26 R.TVMVQEGNVESAYR.T sp|P82921|RT21_HUMAN 1 1581.7457 1.65 47549 13432 2 1581.745803 791.8801 "28S ribosomal protein S21, mitochondrial OS=Homo sapiens OX=9606 GN=MRPS21 PE=1 SV=3" 4.53 2548.8 - 620851 - - - 0.0607 - 2.723 0.546 - 679.6 1 2 0 0.0001 14 0 0 0 7.52E+06 4.56E+06 - - - 5.5875 0.9853 221125_WJC_METTL3_EV_vs_WT_F04.13434.13434.3 0.00367 Nov-36 R.LTIELHPDGR.H sp|Q15545|TAF7_HUMAN 1 1149.6142 1.13 47551 13434 3 1149.613102 384.212 Transcription initiation factor TFIID subunit 7 OS=Homo sapiens OX=9606 GN=TAF7 PE=1 SV=1 5.32 2549.1 - 401941 - - - -0.9742 - 1.815 0.116 - 96.1 1 2 0 -0.0011 10 0 0 0 5.95E+06 5.27E+06 - - - 1.5738 0.9952 221125_WJC_METTL3_EV_vs_WT_F04.13435.13435.2 0.0142 22-Jul K.NNYYGTSIDSVR[166.11].S "sp|Q5T2T1|MPP7_HUMAN,tr|U5GXS2|U5GXS2_HUMAN" 2 1397.6451 0.12 47552 13435 2 1397.644348 699.8298 MAGUK p55 subfamily member 7 OS=Homo sapiens OX=9606 GN=MPP7 PE=1 SV=1 5.83 2549.2 - 369435 - - - -0.5223 - 1.319 0.187 - 137 1 2 0 -0.0007 12 0 0 0 6.17E+05 5.05E+06 - - - 1.1505 0.9998 221125_WJC_METTL3_EV_vs_WT_F04.13438.13438.2 0.000225 20-Nov K.TVETLQQQLSK[136.11].M sp|Q8IWJ2|GCC2_HUMAN 1 1281.702 1.51 47555 13438 2 1281.702826 641.8583 GRIP and coiled-coil domain-containing protein 2 OS=Homo sapiens OX=9606 GN=GCC2 PE=1 SV=4 5.66 2549.6 - 236402 - - - 0.6593 - 2.394 0.449 - 263.9 1 2 0 0.0008 11 0 0 0 1.74E+07 1.15E+07 - - - 4.7186 0.9997 221125_WJC_METTL3_EV_vs_WT_F04.13441.13441.2 0.0784 14-Oct K.IGIEIIKR.T "sp|P10809|CH60_HUMAN,tr|A0A7I2V2X6|A0A7I2V2X6_HUMAN,tr|A0A7I2YQK6|A0A7I2YQK6_HUMAN,tr|A0A7I2V599|A0A7I2V599_HUMAN" 4 940.607 1.09 47556 13441 2 940.606943 471.3108 "60 kDa heat shock protein, mitochondrial OS=Homo sapiens OX=9606 GN=HSPD1 PE=1 SV=2" 8.75 2550 - 3.00E+06 - - - -0.0096 - 2.19 0.283 - 323.9 1 2 0 0 8 0 0 0 2.48E+07 2.28E+07 - - - 3.4954 0.9999 221125_WJC_METTL3_EV_vs_WT_F04.13442.13442.2 0.000449 13/22 R.AQIFANTVDNAR[166.11].L "sp|P05783|K1C18_HUMAN,tr|F8VZY9|F8VZY9_HUMAN" 2 1328.6712 1.96 47557 13442 2 1328.67183 665.3429 "Keratin, type I cytoskeletal 18 OS=Homo sapiens OX=9606 GN=KRT18 PE=1 SV=2" 5.88 2550 - 2.84E+06 - - - 0.4493 - 2.62 0.481 - 542.7 1 2 0 0.0006 12 0 0 0 6.43E+07 3.29E+07 - - - 5.1278 0.9943 221125_WJC_METTL3_EV_vs_WT_F04.13443.13443.3 0.0192 Nov-36 R.RKPFYPALIR.Y "sp|O00746|NDKM_HUMAN,tr|Q4TT34|Q4TT34_HUMAN,tr|H0Y6J0|H0Y6J0_HUMAN,tr|F2Z2X0|F2Z2X0_HUMAN,tr|A2IDC9|A2IDC9_HUMAN" 5 1259.7503 2.01 47558 13443 3 1259.749536 420.924 "Nucleoside diphosphate kinase, mitochondrial OS=Homo sapiens OX=9606 GN=NME4 PE=1 SV=1" 11 2550.1 - 1.97E+06 - - - -0.5763 - 1.808 0.169 - 171.2 1 2 0 -0.0007 10 0 0 0 7.33E+07 3.65E+07 - - - 2.1535 0.9997 221125_WJC_METTL3_EV_vs_WT_F04.13444.13444.3 8.55E-05 14/48 K.FVSEDDR[166.11]NSFTLK[136.11].L "sp|P34932|HSP74_HUMAN,tr|A0A087WYC1|A0A087WYC1_HUMAN" 2 1574.7696 0.07 47559 13444 3 1574.770912 525.9305 Heat shock 70 kDa protein 4 OS=Homo sapiens OX=9606 GN=HSPA4 PE=1 SV=4 4.56 2550.2 - 1.76E+06 - - - 0.8604 - 1.837 0.48 - 119.7 1 2 1 0.0014 13 0 0 0 1.87E+07 2.62E+08 - - - 5.54 1 221125_WJC_METTL3_EV_vs_WT_F04.13445.13445.3 5.28E-06 14/44 R.TFIAIKPDGVQR.G "sp|P15531|NDKA_HUMAN,sp|P22392|NDKB_HUMAN,tr|Q32Q12|Q32Q12_HUMAN,tr|Q32Q12|Q32Q12_HUMAN,tr|J3KPD9|J3KPD9_HUMAN,tr|F6XY72|F6XY72_HUMAN,tr|E5RHP0|E5RHP0_HUMAN,tr|E7ERL0|E7ERL0_HUMAN,tr|C9K028|C9K028_HUMAN" 9 1343.7561 1.38 47560 13445 3 1343.755515 448.926 Nucleoside diphosphate kinase A OS=Homo sapiens OX=9606 GN=NME1 PE=1 SV=1 8.41 2550.2 - 1.65E+06 - - - -0.4614 - 2.56 0.456 - 221.7 1 2 0 -0.0006 12 0 0 0 2.21E+09 1.60E+09 - - - 6.2293 0.9997 221125_WJC_METTL3_EV_vs_WT_F04.13446.13446.2 0.0461 13/14 K.K[136.11]GEIFELK[136.11].A "sp|P63010|AP2B1_HUMAN,sp|Q10567|AP1B1_HUMAN,tr|K7EJX1|K7EJX1_HUMAN,tr|K7ERB2|K7ERB2_HUMAN,tr|A0A087WZQ6|A0A087WZQ6_HUMAN,tr|K7EKZ5|K7EKZ5_HUMAN,tr|A0A087X253|A0A087X253_HUMAN,tr|K7EN71|K7EN71_HUMAN,tr|C9J1E7|C9J1E7_HUMAN,tr|A0A087WXS3|A0A087WXS3_HUMAN,tr|A0A087WU93|A0A087WU93_HUMAN,tr|A0A087WYD1|A0A087WYD1_HUMAN" 12 978.5721 0.61 47561 13446 2 978.571634 490.2933 AP-2 complex subunit beta OS=Homo sapiens OX=9606 GN=AP2B1 PE=1 SV=1 6.14 2550.4 - 1.55E+06 - - - -0.4588 - 2.509 0.228 - 611 1 2 0 -0.0004 8 0 0 0 9.86E+06 1.60E+07 - - - 3.4992 0.9985 221125_WJC_METTL3_EV_vs_WT_F04.13447.13447.3 0.044 13/32 R.EFADFEYR[166.11]K[136.11].T "sp|Q8ND56|LS14A_HUMAN,tr|A0A140TA66|A0A140TA66_HUMAN" 2 1221.5785 1 47562 13447 3 1221.575575 408.2001 Protein LSM14 homolog A OS=Homo sapiens OX=9606 GN=LSM14A PE=1 SV=3 4.68 2550.5 - 803435 - - - -2.401 - 1.974 0.277 - 199.8 1 2 0 -0.0029 9 0 0 0 7.43E+08 7.47E+08 - - - 3.677 0.9999 221125_WJC_METTL3_EV_vs_WT_F04.13448.13448.2 1.29E-05 22-Nov R.FQQVPTDALANK[136.11].L "sp|Q6PKG0|LARP1_HUMAN,tr|A0A0B4J210|A0A0B4J210_HUMAN,tr|H0YC33|H0YC33_HUMAN,tr|E5RH50|E5RH50_HUMAN" 4 1338.7023 1.34 47563 13448 2 1338.701439 670.3584 La-related protein 1 OS=Homo sapiens OX=9606 GN=LARP1 PE=1 SV=2 5.84 2550.6 - 730712 - - - -0.6544 - 2 0.516 - 331.8 1 2 0 -0.0009 12 0 0 0 6.42E+07 4.80E+07 - - - 4.6757 0.9486 221125_WJC_METTL3_EV_vs_WT_F04.13449.13449.3 0.871 Aug-44 R.AQIFANTVDNAR.L "sp|P05783|K1C18_HUMAN,tr|F8VZY9|F8VZY9_HUMAN" 2 1318.663 1.01 47564 13449 3 1318.662821 440.5616 "Keratin, type I cytoskeletal 18 OS=Homo sapiens OX=9606 GN=KRT18 PE=1 SV=2" 5.88 2550.7 - 714525 - - - -0.1077 - 1.429 0.13 - 85.7 2 2 0 -0.0001 12 0 0 0 6.55E+06 6.50E+06 - - - 0.8395 0.9987 221125_WJC_METTL3_EV_vs_WT_F04.13450.13450.2 0.0334 20-Sep K.DVSVTVGMDSR.C sp|Q6KB66|K2C80_HUMAN 1 1164.5445 134.99 47565 13450 2 1164.543793 583.2795 "Keratin, type II cytoskeletal 80 OS=Homo sapiens OX=9606 GN=KRT80 PE=1 SV=2" 4.21 2550.9 - 719329 - - - -0.5959 - 1.298 0.332 - 220.2 1 2 0 -0.0007 11 0 0 0 1.13E+08 8.40E+05 - - - 2.1985 0.9721 221125_WJC_METTL3_EV_vs_WT_F04.13452.13452.2 0.929 16-Jul K.RELLELASR.M "sp|Q00341|VIGLN_HUMAN,tr|A0A024R4E5|A0A024R4E5_HUMAN,tr|H0Y394|H0Y394_HUMAN" 3 1085.6193 0.72 47567 13452 2 1085.618492 543.8169 Vigilin OS=Homo sapiens OX=9606 GN=HDLBP PE=1 SV=2 6.14 2551.1 - 346407 - - - -0.7507 - 1.256 0.069 - 85.1 3 2 0 -0.0008 9 0 0 0 2.49E+06 3.47E+06 - - - -0.0033 0.9998 221125_WJC_METTL3_EV_vs_WT_F04.13456.13456.2 5.99E-05 20-Oct K.LSAMMGAVAEK[136.11].K "sp|Q86U44|MTA70_HUMAN,tr|F5H6D8|F5H6D8_HUMAN,tr|H0YFV6|H0YFV6_HUMAN,tr|B4DTN4|B4DTN4_HUMAN" 4 1114.5606 0.01 47569 13456 2 1114.560541 558.2876 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 6 2551.6 - 2.76E+07 - - - -0.0547 - 2.199 0.375 - 325.2 1 2 0 -0.0001 11 0 0 0 8.29E+06 6.07E+08 - - - 3.9425 1 221125_WJC_METTL3_EV_vs_WT_F04.13457.13457.2 2.01E-08 13/22 R.FLEQQNQVLQTK.W "sp|Q7Z794|K2C1B_HUMAN,sp|P04264|K2C1_HUMAN,sp|P35908|K22E_HUMAN" 3 1474.778 -1 47570 13457 2 1474.776919 738.3963 "Keratin, type II cytoskeletal 1b OS=Homo sapiens OX=9606 GN=KRT77 PE=1 SV=3" 6 2551.7 - 3.48E+06 - - - -0.7282 - 2.71 0.573 - 547.4 1 2 0 -0.0011 12 0 0 0 0.00E+00 0.00E+00 - - - 5.896 0.9999 221125_WJC_METTL3_EV_vs_WT_F04.13458.13458.3 0.0411 Dec-32 R.EFADFEYRK.T "sp|Q8ND56|LS14A_HUMAN,tr|A0A140TA66|A0A140TA66_HUMAN" 2 1203.556 0.98 47571 13458 3 1203.556275 402.1926 Protein LSM14 homolog A OS=Homo sapiens OX=9606 GN=LSM14A PE=1 SV=3 4.68 2551.8 - 1.98E+06 - - - 0.1969 - 2.095 0.413 - 178.8 1 2 0 0.0002 9 0 0 0 7.44E+08 7.62E+08 - - - 5.3733 0.9999 221125_WJC_METTL3_EV_vs_WT_F04.13459.13459.3 9.74E-05 Dec-32 K.MR[166.11]PFEGFQR[166.11].K "sp|Q9BUJ2|HNRL1_HUMAN,tr|A0A0A0MRA5|A0A0A0MRA5_HUMAN,tr|M0R3F1|M0R3F1_HUMAN,tr|B7Z4B8|B7Z4B8_HUMAN" 4 1186.582 1.6 47572 13459 3 1186.583234 396.5346 Heterogeneous nuclear ribonucleoprotein U-like protein 1 OS=Homo sapiens OX=9606 GN=HNRNPUL1 PE=1 SV=2 9.35 2551.8 - 1.90E+06 - - - 1.0079 - 2.26 0.407 - 222.1 1 2 0 0.0012 9 0 0 0 1.01E+08 6.33E+07 - - - 5.5347 0.9999 221125_WJC_METTL3_EV_vs_WT_F04.13464.13464.2 0.0753 22-Nov R.TFIAIK[136.11]PDGVQR[166.11].G "sp|P15531|NDKA_HUMAN,sp|P22392|NDKB_HUMAN,tr|Q32Q12|Q32Q12_HUMAN,tr|Q32Q12|Q32Q12_HUMAN,tr|J3KPD9|J3KPD9_HUMAN,tr|F6XY72|F6XY72_HUMAN,tr|E5RHP0|E5RHP0_HUMAN,tr|E7ERL0|E7ERL0_HUMAN,tr|C9K028|C9K028_HUMAN" 9 1361.7786 1.39 47577 13464 2 1361.778916 681.8966 Nucleoside diphosphate kinase A OS=Homo sapiens OX=9606 GN=NME1 PE=1 SV=1 8.41 2552.5 - 399284 - - - 0.2284 - 2.487 0.427 - 307.5 1 2 0 0.0003 12 0 0 0 2.53E+08 1.82E+08 - - - 4.5919 0.9881 221125_WJC_METTL3_EV_vs_WT_F04.13465.13465.2 2.62E-05 24-Oct K.FVSEDDR[166.11]NSFTLK[136.11].L "sp|P34932|HSP74_HUMAN,tr|A0A087WYC1|A0A087WYC1_HUMAN" 2 1574.7696 0.001 47578 13465 2 1574.775623 788.3921 Heat shock 70 kDa protein 4 OS=Homo sapiens OX=9606 GN=HSPA4 PE=1 SV=4 4.56 2552.6 - 296393 - - - 3.852 - 2.007 0.537 - 216.7 1 2 1 0.0061 13 0 0 0 0.00E+00 1.63E+07 - - - 4.7933 0.9655 221125_WJC_METTL3_EV_vs_WT_F04.13466.13466.2 0.0177 30-Aug R.LLASSPALPSSGAQAR[166.11].L sp|Q9NYZ3|GTSE1_HUMAN 1 1534.8343 1.58 47579 13466 2 1534.826255 768.4244 G2 and S phase-expressed protein 1 OS=Homo sapiens OX=9606 GN=GTSE1 PE=1 SV=3 9.75 2552.7 - 254581 - - - -5.226 - 1.768 0.209 - 104.1 1 2 0 -0.008 16 0 0 0 1.37E+06 8.70E+05 - - - 1.9832 0.9999 221125_WJC_METTL3_EV_vs_WT_F04.13470.13470.3 0.00138 13/36 K.IAGYVTHLMK[136.11].R "sp|P08708|RS17_HUMAN,tr|H3BNC9|H3BNC9_HUMAN,tr|H0YN88|H0YN88_HUMAN,tr|A0A075B716|A0A075B716_HUMAN" 4 1139.6253 0.001 47582 13470 3 1139.62465 380.8824 40S ribosomal protein S17 OS=Homo sapiens OX=9606 GN=RPS17 PE=1 SV=2 8.6 2553.2 - 2.10E+06 - - - -0.5274 - 1.955 0.408 - 151.4 1 2 0 -0.0006 10 0 0 0 0.00E+00 2.45E+07 - - - 5.0465 0.999 221125_WJC_METTL3_EV_vs_WT_F04.13472.13472.3 0.000245 13/40 R.EIAQDFKTDLR.F "sp|Q16695|H31T_HUMAN,sp|P84243|H33_HUMAN,sp|Q71DI3|H32_HUMAN,sp|P68431|H31_HUMAN,tr|B4DEB1|B4DEB1_HUMAN,tr|K7EK07|K7EK07_HUMAN,tr|K7ES00|K7ES00_HUMAN,tr|K7EMV3|K7EMV3_HUMAN,tr|A0A590UJJ6|A0A590UJJ6_HUMAN" 9 1334.683 1.12 47583 13472 3 1334.679585 445.9016 Histone H3.1t OS=Homo sapiens OX=9606 GN=H3-4 PE=1 SV=3 4.56 2553.4 - 2.73E+06 - - - -2.5811 - 2.125 0.425 - 266 1 2 1 -0.0034 11 0 0 0 3.58E+07 3.19E+07 - - - 5.4187 1 221125_WJC_METTL3_EV_vs_WT_F04.13473.13473.3 2.11E-06 14/44 R.FLEQQNQVLQTK.W "sp|Q7Z794|K2C1B_HUMAN,sp|P04264|K2C1_HUMAN,sp|P35908|K22E_HUMAN" 3 1474.778 5502.26 47584 13473 3 1474.777627 492.5999 "Keratin, type II cytoskeletal 1b OS=Homo sapiens OX=9606 GN=KRT77 PE=1 SV=3" 6 2553.5 - 2.86E+06 - - - -0.2482 - 2.463 0.514 - 251.2 1 2 0 -0.0004 12 0 0 0 2.73E+09 4.96E+05 - - - 6.769 1 221125_WJC_METTL3_EV_vs_WT_F04.13475.13475.3 1.16E-05 14/48 K.VVQLHEYSEELEK[136.11].L "sp|Q14683|SMC1A_HUMAN,tr|G8JLG1|G8JLG1_HUMAN,tr|A0A6Q8PHC3|A0A6Q8PHC3_HUMAN" 3 1609.8079 1.08 47586 13475 3 1609.807889 537.6099 Structural maintenance of chromosomes protein 1A OS=Homo sapiens OX=9606 GN=SMC1A PE=1 SV=2 4.48 2553.6 - 2.03E+06 - - - -0.0087 - 2.49 0.482 - 246.7 1 2 0 0 13 0 0 0 3.85E+07 3.56E+07 - - - 6.3873 0.9999 221125_WJC_METTL3_EV_vs_WT_F04.13476.13476.3 2.96E-05 Oct-48 K.VVQLHEYSEELEK.L "sp|Q14683|SMC1A_HUMAN,tr|G8JLG1|G8JLG1_HUMAN,tr|A0A6Q8PHC3|A0A6Q8PHC3_HUMAN" 3 1601.7937 1.08 47587 13476 3 1601.795087 534.9385 Structural maintenance of chromosomes protein 1A OS=Homo sapiens OX=9606 GN=SMC1A PE=1 SV=2 4.48 2553.7 - 1.98E+06 - - - 0.864 - 2.201 0.44 - 104.3 1 2 0 0.0014 13 0 0 0 3.85E+07 3.56E+07 - - - 5.5841 0.9997 221125_WJC_METTL3_EV_vs_WT_F04.13477.13477.2 0.000114 15/26 K.LNEAQPSTIATSMR.D "sp|P56537|IF6_HUMAN,tr|A0A0U1RQV5|A0A0U1RQV5_HUMAN" 2 1517.7508 1.85 47588 13477 2 1517.754717 759.8827 Eukaryotic translation initiation factor 6 OS=Homo sapiens OX=9606 GN=EIF6 PE=1 SV=1 6 2553.8 - 1.38E+06 - - - 2.5861 - 2.859 0.487 - 521.6 1 2 0 0.0039 14 0 0 0 5.28E+07 2.86E+07 - - - 5.2729 0.9979 221125_WJC_METTL3_EV_vs_WT_F04.13479.13479.3 0.00244 Nov-48 K.FVSEDDRNSFTLK.L "sp|P34932|HSP74_HUMAN,tr|A0A087WYC1|A0A087WYC1_HUMAN" 2 1556.7471 0.07 47590 13479 3 1556.748553 519.923 Heat shock 70 kDa protein 4 OS=Homo sapiens OX=9606 GN=HSPA4 PE=1 SV=4 4.56 2554 - 819371 - - - 0.9417 - 1.63 0.365 - 86.6 1 2 1 0.0015 13 0 0 0 1.87E+07 2.61E+08 - - - 3.9337 0.9999 221125_WJC_METTL3_EV_vs_WT_F04.13480.13480.2 0.00268 13/22 R.TFIAIKPDGVQR.G "sp|P15531|NDKA_HUMAN,sp|P22392|NDKB_HUMAN,tr|Q32Q12|Q32Q12_HUMAN,tr|Q32Q12|Q32Q12_HUMAN,tr|J3KPD9|J3KPD9_HUMAN,tr|F6XY72|F6XY72_HUMAN,tr|E5RHP0|E5RHP0_HUMAN,tr|E7ERL0|E7ERL0_HUMAN,tr|C9K028|C9K028_HUMAN" 9 1343.7561 1.39 47591 13480 2 1343.757256 672.8853 Nucleoside diphosphate kinase A OS=Homo sapiens OX=9606 GN=NME1 PE=1 SV=1 8.41 2554.1 - 683389 - - - 0.8342 - 2.641 0.503 - 770.2 1 2 0 0.0011 12 0 0 0 2.53E+08 1.82E+08 - - - 5.3111 0.8829 221125_WJC_METTL3_EV_vs_WT_F04.13481.13481.2 0.33 18-Sep F.IAIKPDGVQR.G "sp|P15531|NDKA_HUMAN,sp|P22392|NDKB_HUMAN,tr|Q32Q12|Q32Q12_HUMAN,tr|Q32Q12|Q32Q12_HUMAN,tr|J3KPD9|J3KPD9_HUMAN,tr|J3KPD9|J3KPD9_HUMAN,tr|F6XY72|F6XY72_HUMAN,tr|E5RHP0|E5RHP0_HUMAN,tr|E7ERL0|E7ERL0_HUMAN,tr|C9K028|C9K028_HUMAN" 10 1095.64 1.56 47592 13481 2 1095.641865 548.8273 Nucleoside diphosphate kinase A OS=Homo sapiens OX=9606 GN=NME1 PE=1 SV=1 8.75 2554.2 - 625576 - - - 1.663 - 1.731 0.225 - 254 1 1 0 0.0018 10 0 0 0 1.38E+08 8.84E+07 - - - 2.2339 0.992 221125_WJC_METTL3_EV_vs_WT_F04.13485.13485.3 0.136 Sep-44 K.LQGIGHFQNTIR.E "sp|Q03001|DYST_HUMAN,tr|E9PHM6|E9PHM6_HUMAN,tr|F8W9J4|F8W9J4_HUMAN,tr|A0A7P0T890|A0A7P0T890_HUMAN,tr|F6QMI7|F6QMI7_HUMAN" 5 1382.7419 0.91 47596 13485 3 1382.745841 461.9212 Dystonin OS=Homo sapiens OX=9606 GN=DST PE=1 SV=4 9.76 2554.8 - 356979 - - - 2.8632 - 1.602 0.259 - 87.1 1 2 0 0.004 12 0 0 0 5.15E+06 5.68E+06 - - - 2.7327 0.9998 221125_WJC_METTL3_EV_vs_WT_F04.13489.13489.3 3.43E-05 13/40 K.MK[136.11]EIAEAYLGK[136.11].T "sp|P11142|HSP7C_HUMAN,tr|E9PQQ4|E9PQQ4_HUMAN,tr|E9PKE3|E9PKE3_HUMAN,tr|E9PN89|E9PN89_HUMAN,tr|E9PLF4|E9PLF4_HUMAN,tr|E9PI65|E9PI65_HUMAN,tr|E9PK54|E9PK54_HUMAN,tr|E9PPY6|E9PPY6_HUMAN,tr|E9PQK7|E9PQK7_HUMAN" 9 1267.6817 0.14 47598 13489 3 1267.679628 423.5678 Heat shock cognate 71 kDa protein OS=Homo sapiens OX=9606 GN=HSPA8 PE=1 SV=1 5.9 2555.3 - 1.60E+07 - - - -1.6424 - 2.431 0.518 - 306.3 1 2 1 -0.0021 11 0 0 0 4.33E+07 3.02E+08 - - - 6.8381 0.9994 221125_WJC_METTL3_EV_vs_WT_F04.13491.13491.2 0.00193 16-Aug R.EFADFEYR[166.11]K[136.11].T "sp|Q8ND56|LS14A_HUMAN,tr|A0A140TA66|A0A140TA66_HUMAN" 2 1221.5785 0.89 47600 13491 2 1221.576659 611.7965 Protein LSM14 homolog A OS=Homo sapiens OX=9606 GN=LSM14A PE=1 SV=3 4.68 2555.4 - 4.96E+06 - - - -1.5136 - 1.465 0.44 - 283.6 1 2 0 -0.0019 9 0 0 0 1.35E+08 1.51E+08 - - - 3.395 0.9934 221125_WJC_METTL3_EV_vs_WT_F04.13492.13492.2 0.0136 16-Aug R.EFADFEYRK.T "sp|Q8ND56|LS14A_HUMAN,tr|A0A140TA66|A0A140TA66_HUMAN" 2 1203.556 0.88 47601 13492 2 1203.560461 602.7853 Protein LSM14 homolog A OS=Homo sapiens OX=9606 GN=LSM14A PE=1 SV=3 4.68 2555.5 - 2.64E+06 - - - 3.6749 - 1.419 0.329 - 229.9 1 2 0 0.0044 9 0 0 0 1.35E+08 1.54E+08 - - - 2.482 0.9999 221125_WJC_METTL3_EV_vs_WT_F04.13493.13493.2 8.16E-06 14/26 K.LNEAQPSTIATSMR[166.11].D "sp|P56537|IF6_HUMAN,tr|A0A0U1RQV5|A0A0U1RQV5_HUMAN" 2 1527.7591 1.85 47602 13493 2 1527.756738 764.8868 Eukaryotic translation initiation factor 6 OS=Homo sapiens OX=9606 GN=EIF6 PE=1 SV=1 6 2555.5 - 1.62E+06 - - - -1.5212 - 2.995 0.517 - 357.5 1 2 0 -0.0023 14 0 0 0 5.28E+07 2.86E+07 - - - 5.6116 1 221125_WJC_METTL3_EV_vs_WT_F04.13494.13494.3 2.70E-06 16/40 R.LEAMC[160.03]FDGVKR.L "sp|P47813|IF1AX_HUMAN,tr|X6RAC9|X6RAC9_HUMAN" 2 1324.6268 0.56 47603 13494 3 1324.625654 442.5495 "Eukaryotic translation initiation factor 1A, X-chromosomal OS=Homo sapiens OX=9606 GN=EIF1AX PE=1 SV=2" 6.06 2555.7 - 1.05E+06 - - - -0.8485 - 2.76 0.475 - 543.7 1 2 0 -0.0011 11 0 0 0 9.13E+07 1.65E+08 - - - 6.7196 0.9972 221125_WJC_METTL3_EV_vs_WT_F04.13495.13495.3 1.58E-05 Dec-44 R.IFDSPEELPKER.S "sp|P35658|NU214_HUMAN,tr|A0A494BZU9|A0A494BZU9_HUMAN,tr|A0A494C1F2|A0A494C1F2_HUMAN" 3 1458.7355 7.31 47604 13495 3 1458.737751 487.2524 Nuclear pore complex protein Nup214 OS=Homo sapiens OX=9606 GN=NUP214 PE=1 SV=2 4.41 2555.8 - 983172 - - - 1.5712 - 2.218 0.29 - 164 1 2 1 0.0023 12 0 0 0 5.98E+06 8.18E+05 - - - 3.9807 0.9955 221125_WJC_METTL3_EV_vs_WT_F04.13500.13500.2 0.00485 18-Oct R.DYTQMNELQR[166.11].R "sp|P07203|GPX1_HUMAN,tr|A0A7I2YMD7|A0A7I2YMD7_HUMAN,tr|A0A7I2UQ36|A0A7I2UQ36_HUMAN" 3 1306.5851 1.71 47609 13500 2 1306.577859 654.2998 Glutathione peroxidase 1 OS=Homo sapiens OX=9606 GN=GPX1 PE=1 SV=4 4.37 2556.4 - 448640 - - - -5.5572 - 1.989 0.469 - 405.4 1 2 0 -0.0073 10 0 0 0 6.52E+06 3.81E+06 - - - 4.4221 0.9995 221125_WJC_METTL3_EV_vs_WT_F04.13503.13503.2 0.0217 16-Jul K.MR[166.11]PFEGFQR[166.11].K "sp|Q9BUJ2|HNRL1_HUMAN,tr|A0A0A0MRA5|A0A0A0MRA5_HUMAN,tr|M0R3F1|M0R3F1_HUMAN,tr|B7Z4B8|B7Z4B8_HUMAN" 4 1186.582 0.35 47612 13503 2 1186.581558 594.2983 Heterogeneous nuclear ribonucleoprotein U-like protein 1 OS=Homo sapiens OX=9606 GN=HNRNPUL1 PE=1 SV=2 9.35 2556.8 - 340876 - - - -0.4045 - 1.505 0.37 - 127.6 1 2 0 -0.0005 9 0 0 0 5.61E+06 1.58E+07 - - - 2.9563 0.999 221125_WJC_METTL3_EV_vs_WT_F04.13505.13505.2 8.69E-06 16/20 K.MK[136.11]EIAEAYLGK[136.11].T "sp|P11142|HSP7C_HUMAN,tr|E9PQQ4|E9PQQ4_HUMAN,tr|E9PKE3|E9PKE3_HUMAN,tr|E9PN89|E9PN89_HUMAN,tr|E9PLF4|E9PLF4_HUMAN,tr|E9PI65|E9PI65_HUMAN,tr|E9PK54|E9PK54_HUMAN,tr|E9PPY6|E9PPY6_HUMAN,tr|E9PQK7|E9PQK7_HUMAN" 9 1267.6817 0.12 47613 13505 2 1267.681154 634.8481 Heat shock cognate 71 kDa protein OS=Homo sapiens OX=9606 GN=HSPA8 PE=1 SV=1 5.9 2557 - 1.38E+06 - - - -0.4386 - 2.757 0.508 - 634 1 2 1 -0.0006 11 0 0 0 6.00E+06 4.87E+07 - - - 5.5364 0.9298 221125_WJC_METTL3_EV_vs_WT_F04.13507.13507.3 0.183 Aug-36 R.LKYENELALR.Q "sp|P19012|K1C15_HUMAN,sp|P13646|K1C13_HUMAN,tr|K7EMD9|K7EMD9_HUMAN,tr|K7ERE3|K7ERE3_HUMAN" 4 1247.6874 96.03 47614 13507 3 1247.684496 416.9031 "Keratin, type I cytoskeletal 15 OS=Homo sapiens OX=9606 GN=KRT15 PE=1 SV=3" 6.14 2557.2 - 3.57E+06 - - - -2.3171 - 1.721 0.169 - 90.5 1 2 1 -0.0029 10 0 0 0 6.64E+07 6.92E+05 - - - 2.0089 0.9993 221125_WJC_METTL3_EV_vs_WT_F04.13508.13508.3 0.00966 Nov-40 R.LTISSPLEAHK.A sp|Q15393|SF3B3_HUMAN 1 1194.6608 1.1 47615 13508 3 1194.658118 399.2276 Splicing factor 3B subunit 3 OS=Homo sapiens OX=9606 GN=SF3B3 PE=1 SV=4 6.75 2557.3 - 2.13E+06 - - - -2.2768 - 2.255 0.303 - 132.8 1 2 0 -0.0027 11 0 0 0 1.02E+08 9.24E+07 - - - 4.2274 0.9999 221125_WJC_METTL3_EV_vs_WT_F04.13511.13511.2 2.50E-05 15/26 K.AVTELNEPLSNEDR[166.11].N sp|Q04917|1433F_HUMAN 1 1595.7667 1.32 47618 13511 2 1595.765333 798.8906 14-3-3 protein eta OS=Homo sapiens OX=9606 GN=YWHAH PE=1 SV=4 4 2557.5 - 2.27E+06 - - - -0.8253 - 3.174 0.506 - 604.2 1 2 0 -0.0013 14 0 0 0 3.02E+07 2.29E+07 - - - 5.6763 0.9998 221125_WJC_METTL3_EV_vs_WT_F04.13515.13515.2 9.20E-05 18/22 R.K[136.11]AVDEAADALLK[136.11].A "sp|Q16891|MIC60_HUMAN,tr|B9A067|B9A067_HUMAN,tr|C9J406|C9J406_HUMAN,tr|H7C463|H7C463_HUMAN" 4 1258.7104 0.78 47622 13515 2 1258.707626 630.3625 MICOS complex subunit MIC60 OS=Homo sapiens OX=9606 GN=IMMT PE=1 SV=1 4.56 2558 - 695597 - - - -2.1776 - 3.165 0.487 - 963.9 1 2 0 -0.0027 12 0 0 0 2.72E+07 3.49E+07 - - - 5.6686 0.9994 221125_WJC_METTL3_EV_vs_WT_F04.13518.13518.2 0.000237 22-Sep R.AQPSVSLGAAYR[166.11].A sp|Q96PK6|RBM14_HUMAN 1 1228.644 1.93 47624 13518 2 1228.641079 615.3293 RNA-binding protein 14 OS=Homo sapiens OX=9606 GN=RBM14 PE=1 SV=2 8.79 2558.4 - 2.02E+06 - - - -2.3416 - 2.094 0.401 - 260.5 1 2 0 -0.0029 12 0 0 0 8.71E+08 4.52E+08 - - - 3.9465 0.9159 221125_WJC_METTL3_EV_vs_WT_F04.13520.13520.2 0.138 12-Sep F.ADFEYR[166.11]K[136.11].T "sp|Q8ND56|LS14A_HUMAN,tr|A0A140TA66|A0A140TA66_HUMAN" 2 945.4675 0.96 47625 13520 2 945.466947 473.741 Protein LSM14 homolog A OS=Homo sapiens OX=9606 GN=LSM14A PE=1 SV=3 6.11 2558.6 - 3.00E+06 - - - -0.586 - 1.572 0.213 - 319.1 1 1 0 -0.0006 7 0 0 0 4.02E+07 4.19E+07 - - - 2.0473 0.9998 221125_WJC_METTL3_EV_vs_WT_F04.13522.13522.2 1.30E-05 24-Dec K.QQVPSGESAILDR.V "sp|P09874|PARP1_HUMAN,tr|A0A7I2V5E9|A0A7I2V5E9_HUMAN,tr|A0A7I2V625|A0A7I2V625_HUMAN,tr|A0A7I2V3E1|A0A7I2V3E1_HUMAN" 4 1398.7103 1.15 47627 13522 2 1398.708941 700.3624 Poly [ADP-ribose] polymerase 1 OS=Homo sapiens OX=9606 GN=PARP1 PE=1 SV=4 4.37 2558.7 - 5.07E+06 - - - -0.9766 - 2.182 0.424 - 351.8 1 2 0 -0.0014 13 0 0 0 2.80E+08 2.43E+08 - - - 4.1747 1 221125_WJC_METTL3_EV_vs_WT_F04.13524.13524.2 0.000199 19/22 R.KAVDEAADALLK.A "sp|Q16891|MIC60_HUMAN,tr|B9A067|B9A067_HUMAN,tr|C9J406|C9J406_HUMAN,tr|H7C463|H7C463_HUMAN" 4 1242.682 0.78 47629 13524 2 1242.675245 622.3483 MICOS complex subunit MIC60 OS=Homo sapiens OX=9606 GN=IMMT PE=1 SV=1 4.56 2558.9 - 1.24E+06 - - - -5.4093 - 2.993 0.529 - 996.1 1 2 0 -0.0067 12 0 0 0 2.72E+07 3.49E+07 - - - 5.8306 0.9999 221125_WJC_METTL3_EV_vs_WT_F04.13525.13525.3 0.00289 14/44 R.K[136.11]AVDEAADALLK[136.11].A "sp|Q16891|MIC60_HUMAN,tr|B9A067|B9A067_HUMAN,tr|C9J406|C9J406_HUMAN,tr|H7C463|H7C463_HUMAN" 4 1258.7104 1.84 47630 13525 3 1258.708052 420.5774 MICOS complex subunit MIC60 OS=Homo sapiens OX=9606 GN=IMMT PE=1 SV=1 4.56 2559 - 1.09E+06 - - - -1.8392 - 2.508 0.436 - 294.9 1 2 0 -0.0023 12 0 0 0 3.69E+07 2.00E+07 - - - 5.949 0.9999 221125_WJC_METTL3_EV_vs_WT_F04.13527.13527.3 0.0002 14/44 K.MHQVMSIEEVER.L "sp|Q96FZ7|CHMP6_HUMAN,tr|I3L4A1|I3L4A1_HUMAN,tr|I3L3E4|I3L3E4_HUMAN,tr|I3L4G8|I3L4G8_HUMAN" 4 1486.6908 2.02 47632 13527 3 1486.687589 496.5709 Charged multivesicular body protein 6 OS=Homo sapiens OX=9606 GN=CHMP6 PE=1 SV=3 4.75 2559.3 - 835182 - - - -2.1827 - 2.508 0.483 - 308.7 1 2 0 -0.0032 12 0 0 0 4.85E+07 2.41E+07 - - - 6.4728 1 221125_WJC_METTL3_EV_vs_WT_F04.13531.13531.2 6.84E-08 15/24 K.EISEGDEVEVYSR.A "sp|P51114|FXR1_HUMAN,tr|C9JAJ4|C9JAJ4_HUMAN,tr|B4DXZ6|B4DXZ6_HUMAN" 3 1510.6787 1.96 47634 13531 2 1510.674847 756.3466 Fragile X mental retardation syndrome-related protein 1 OS=Homo sapiens OX=9606 GN=FXR1 PE=1 SV=3 3.91 2559.8 - 1.77E+06 - - - -2.5717 - 2.631 0.698 - 753.1 1 2 0 -0.0039 13 0 0 0 1.34E+08 6.86E+07 - - - 6.678 0.9894 221125_WJC_METTL3_EV_vs_WT_F04.13532.13532.3 0.000134 Dec-40 R.ERPAAISIEIK.S sp|Q15208|STK38_HUMAN 1 1225.703 3.73 47635 13532 3 1226.702904 409.575 Serine\threonine-protein kinase 38 OS=Homo sapiens OX=9606 GN=STK38 PE=1 SV=1 6.24 2559.9 - 1.10E+07 - - - 815.7498 - 2.19 0.413 - 174 1 2 0 0.9999 11 0 0 0 4.12E+08 1.11E+08 - - - 5.0945 0.9989 221125_WJC_METTL3_EV_vs_WT_F04.13534.13534.2 0.017 18-Dec K.YQELQITAGR.H sp|Q7Z794|K2C1B_HUMAN 1 1177.6091 999 47637 13534 2 1177.609451 589.8118 "Keratin, type II cytoskeletal 1b OS=Homo sapiens OX=9606 GN=KRT77 PE=1 SV=3" 6 2560.1 - 2.10E+06 - - - 0.2666 - 1.788 0.221 - 340 1 2 0 0.0003 10 0 0 0 2.30E+07 0.00E+00 - - - 2.2952 0.9024 221125_WJC_METTL3_EV_vs_WT_F04.13535.13535.2 2.31 28-Jul -.MSDAAVDTSSEITTK.D "sp|P06454|PTMA_HUMAN,tr|B8ZZQ6|B8ZZQ6_HUMAN" 2 1554.7083 999 47638 13535 2 1554.706251 778.3614 Prothymosin alpha OS=Homo sapiens OX=9606 GN=PTMA PE=1 SV=2 4.03 2560.2 - 1.25E+06 - - - -1.3295 - 1.076 0.033 - 78 2 2 0 -0.0021 15 0 0 0 5.30E+07 0.00E+00 - - - -0.6703 0.9997 221125_WJC_METTL3_EV_vs_WT_F04.13536.13536.2 7.58E-08 14/22 K.QVATALQNLQTK.T sp|P18206|VINC_HUMAN 1 1313.7303 8.75 47639 13536 2 1313.726779 657.8724 Vinculin OS=Homo sapiens OX=9606 GN=VCL PE=1 SV=4 8.75 2560.3 - 701879 - - - -2.6908 - 2.703 0.536 - 698.7 1 2 0 -0.0035 12 0 0 0 1.11E+07 1.27E+06 - - - 5.6151 1 221125_WJC_METTL3_EV_vs_WT_F04.13538.13538.2 4.00E-05 13/26 K.AVTELNEPLSNEDR.N sp|Q04917|1433F_HUMAN 1 1585.7584 1.32 47640 13538 2 1585.756679 793.8865 14-3-3 protein eta OS=Homo sapiens OX=9606 GN=YWHAH PE=1 SV=4 4 2560.5 - 1.10E+06 - - - -1.0727 - 2.828 0.552 - 364.2 1 2 0 -0.0017 14 0 0 0 3.02E+07 2.29E+07 - - - 5.7263 0.9993 221125_WJC_METTL3_EV_vs_WT_F04.13540.13540.3 0.000903 Oct-40 R.ER[166.11]PAAISIEIK[136.11].S sp|Q15208|STK38_HUMAN 1 1243.7255 3.73 47641 13540 3 1243.722019 415.5824 Serine\threonine-protein kinase 38 OS=Homo sapiens OX=9606 GN=STK38 PE=1 SV=1 6.24 2560.7 - 5.68E+06 - - - -2.8045 - 2.133 0.346 - 140.8 1 2 0 -0.0035 11 0 0 0 4.12E+08 1.11E+08 - - - 4.5486 0.9719 221125_WJC_METTL3_EV_vs_WT_F04.13541.13541.3 0.153 Oct-44 K.APLYDLAAHEDK[136.11].V sp|Q9GZL7|WDR12_HUMAN 1 1349.6707 1.52 47642 13541 3 1349.665551 450.8975 Ribosome biogenesis protein WDR12 OS=Homo sapiens OX=9606 GN=WDR12 PE=1 SV=2 4.54 2560.8 - 8.49E+06 - - - -3.8009 - 1.404 0.256 - 93.8 1 2 0 -0.0051 12 0 0 0 6.46E+07 4.25E+07 - - - 2.3333 1 221125_WJC_METTL3_EV_vs_WT_F04.13543.13543.2 4.20E-06 14/24 K.EISEGDEVEVYSR[166.11].A "sp|P51114|FXR1_HUMAN,tr|C9JAJ4|C9JAJ4_HUMAN,tr|B4DXZ6|B4DXZ6_HUMAN" 3 1520.687 1.96 47644 13543 2 1520.683323 761.3508 Fragile X mental retardation syndrome-related protein 1 OS=Homo sapiens OX=9606 GN=FXR1 PE=1 SV=3 3.91 2561 - 2.76E+06 - - - -2.4193 - 2.494 0.624 - 699.1 1 2 0 -0.0037 13 0 0 0 1.34E+08 6.86E+07 - - - 5.9942 0.9747 221125_WJC_METTL3_EV_vs_WT_F04.13545.13545.2 0.00246 16-Jun K.YVHYEIDAC[160.03].M "sp|Q86U44|MTA70_HUMAN,tr|H0YFV6|H0YFV6_HUMAN" 2 1168.4859 - 47646 13545 2 1168.485486 585.2502 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 4.35 2561.2 - 1.78E+06 - - - -0.3629 - 1.335 0.447 - 117.9 1 1 0 -0.0004 9 0 0 0 - - - - - 3.1783 0.7849 221125_WJC_METTL3_EV_vs_WT_F04.13548.13548.2 0.379 18-Oct F.IAIK[136.11]PDGVQR[166.11].G "sp|P15531|NDKA_HUMAN,sp|P22392|NDKB_HUMAN,tr|Q32Q12|Q32Q12_HUMAN,tr|Q32Q12|Q32Q12_HUMAN,tr|J3KPD9|J3KPD9_HUMAN,tr|J3KPD9|J3KPD9_HUMAN,tr|F6XY72|F6XY72_HUMAN,tr|E5RHP0|E5RHP0_HUMAN,tr|E7ERL0|E7ERL0_HUMAN,tr|C9K028|C9K028_HUMAN" 10 1113.6625 1.56 47647 13548 2 1113.659915 557.8385 Nucleoside diphosphate kinase A OS=Homo sapiens OX=9606 GN=NME1 PE=1 SV=1 8.75 2561.6 - 5.07E+06 - - - -2.3328 - 1.555 0.226 - 321.6 1 1 0 -0.0026 10 0 0 0 1.38E+08 8.84E+07 - - - 1.9417 0.9143 221125_WJC_METTL3_EV_vs_WT_F04.13549.13549.2 0.0042 14-Aug E.FADFEYRK.T "sp|Q8ND56|LS14A_HUMAN,tr|A0A140TA66|A0A140TA66_HUMAN" 2 1074.5134 0.43 47648 13549 2 1074.512418 538.264 Protein LSM14 homolog A OS=Homo sapiens OX=9606 GN=LSM14A PE=1 SV=3 6.07 2561.8 - 1.24E+06 - - - -0.9558 - 1.656 0.212 - 170.4 1 1 0 -0.001 8 0 0 0 6.12E+06 1.43E+07 - - - 2.1278 1 221125_WJC_METTL3_EV_vs_WT_F04.13553.13553.2 6.64E-06 14/22 R.WFEENASQSTVK.V "sp|Q12905|ILF2_HUMAN,tr|B4DY09|B4DY09_HUMAN" 2 1424.6572 1.23 47650 13553 2 1424.651868 713.3359 Interleukin enhancer-binding factor 2 OS=Homo sapiens OX=9606 GN=ILF2 PE=1 SV=2 4.53 2562.2 - 2.96E+06 - - - -3.749 - 2.55 0.572 - 707.6 1 2 0 -0.0053 12 0 0 0 7.62E+07 6.18E+07 - - - 5.7271 1 221125_WJC_METTL3_EV_vs_WT_F04.13554.13554.2 4.75E-08 20/32 R.AIGGGLSSVGGGSSTIK.Y "sp|P48668|K2C6C_HUMAN,sp|P02538|K2C6A_HUMAN" 2 1446.7678 79.32 47651 13554 2 1446.768501 724.3912 "Keratin, type II cytoskeletal 6C OS=Homo sapiens OX=9606 GN=KRT6C PE=1 SV=3" 8.8 2562.3 - 2.20E+06 - - - 0.4693 - 3.458 0.582 - 1087.8 1 2 0 0.0007 17 0 0 0 4.98E+07 6.28E+05 - - - 6.3897 0.999 221125_WJC_METTL3_EV_vs_WT_F04.13556.13556.2 0.0146 14/20 R.ERPAAISIEIK.S sp|Q15208|STK38_HUMAN 1 1225.703 4.5 47653 13556 2 1225.700761 613.8588 Serine\threonine-protein kinase 38 OS=Homo sapiens OX=9606 GN=STK38 PE=1 SV=1 6.24 2562.5 - 4.98E+06 - - - -1.8569 - 2.272 0.241 - 536.5 1 2 0 -0.0023 11 0 0 0 8.41E+07 1.87E+07 - - - 3.0404 0.8734 221125_WJC_METTL3_EV_vs_WT_F04.13557.13557.3 0.0966 Nov-44 R.LSEFIPAVFRLK[136.11].D sp|Q12768|WASC5_HUMAN 1 1426.8428 - 47654 13557 3 1426.847507 476.6215 WASH complex subunit 5 OS=Homo sapiens OX=9606 GN=WASHC5 PE=1 SV=1 8.75 2562.6 - 1.64E+06 - - - 3.3185 - 1.502 0.216 - 99.4 1 2 1 0.0047 12 0 0 0 - - - - - 2.0745 0.9996 221125_WJC_METTL3_EV_vs_WT_F04.13561.13561.3 0.0019 Dec-40 R.ERPAAISIEIK.S sp|Q15208|STK38_HUMAN 1 1225.703 3.73 47656 13561 3 1225.699436 409.575 Serine\threonine-protein kinase 38 OS=Homo sapiens OX=9606 GN=STK38 PE=1 SV=1 6.24 2563.1 - 2.21E+07 - - - -2.9379 - 2.044 0.397 - 160.3 1 2 0 -0.0036 11 0 0 0 4.12E+08 1.11E+08 - - - 4.9961 0.9999 221125_WJC_METTL3_EV_vs_WT_F04.13563.13563.3 1.12E-05 17/40 K.DVLLQVDDER[166.11]R[166.11].N sp|P35579|MYH9_HUMAN 1 1376.7163 0.96 47658 13563 3 1376.711607 459.9127 Myosin-9 OS=Homo sapiens OX=9606 GN=MYH9 PE=1 SV=4 4.23 2563.3 - 1.59E+06 - - - -3.3965 - 2.82 0.535 - 437 1 2 0 -0.0047 11 0 0 0 5.11E+07 5.30E+07 - - - 7.4486 0.9976 221125_WJC_METTL3_EV_vs_WT_F04.13565.13565.2 0.000503 20-Oct K.AQIWDTAGQER.Y "sp|Q15907|RB11B_HUMAN,sp|P62491|RB11A_HUMAN,tr|H3BMH2|H3BMH2_HUMAN,tr|H3BSC1|H3BSC1_HUMAN" 4 1273.6051 1.1 47660 13565 2 1273.602075 637.8098 Ras-related protein Rab-11B OS=Homo sapiens OX=9606 GN=RAB11B PE=1 SV=4 4.37 2563.6 - 777172 - - - -2.3861 - 1.879 0.24 - 357.8 1 2 0 -0.003 11 0 0 0 1.09E+08 9.93E+07 - - - 2.519 1 221125_WJC_METTL3_EV_vs_WT_F04.13568.13568.2 7.39E-07 13/22 R.WFEENASQSTVK[136.11].V "sp|Q12905|ILF2_HUMAN,tr|B4DY09|B4DY09_HUMAN" 2 1432.6714 1.24 47661 13568 2 1432.665359 717.343 Interleukin enhancer-binding factor 2 OS=Homo sapiens OX=9606 GN=ILF2 PE=1 SV=2 4.53 2564 - 3.52E+06 - - - -4.2229 - 2.326 0.678 - 575.7 1 2 0 -0.006 12 0 0 0 7.54E+07 6.07E+07 - - - 6.2679 1 221125_WJC_METTL3_EV_vs_WT_F04.13569.13569.2 5.96E-09 24-Oct K.EYLEAEENGDLER.M "sp|Q96DF8|ESS2_HUMAN,tr|F8WEF8|F8WEF8_HUMAN" 2 1565.6845 2.34 47662 13569 2 1565.678621 783.8495 Splicing factor ESS-2 homolog OS=Homo sapiens OX=9606 GN=ESS2 PE=1 SV=1 3.83 2564.1 - 1.09E+06 - - - -3.7843 - 2.358 0.633 - 285 1 2 0 -0.0059 13 0 0 0 3.40E+07 1.46E+07 - - - 5.9161 0.9885 221125_WJC_METTL3_EV_vs_WT_F04.13570.13570.3 0.256 Jun-44 R.RIHTGAR[166.11]PYEC[160.03]K.E "sp|Q8N9K5|ZN565_HUMAN,tr|K7EL42|K7EL42_HUMAN" 2 1496.7546 - 47663 13570 3 1496.752728 499.9255 Zinc finger protein 565 OS=Homo sapiens OX=9606 GN=ZNF565 PE=2 SV=2 9.31 2564.1 - 6.37E+06 - - - -1.2414 - 1.445 0.235 - 15.3 7 2 0 -0.0019 12 0 0 0 - - - - - 1.7887 0.9999 221125_WJC_METTL3_EV_vs_WT_F04.13574.13574.3 1.93E-06 17/52 K.LNHVAAGLVSPSLK.S "sp|Q05519|SRS11_HUMAN,tr|Q5T760|Q5T760_HUMAN,tr|Q5T757|Q5T757_HUMAN" 3 1404.8089 1.17 47667 13574 3 1404.806899 469.2769 Serine\arginine-rich splicing factor 11 OS=Homo sapiens OX=9606 GN=SRSF11 PE=1 SV=1 8.76 2564.6 - 1.02E+06 - - - -1.4237 - 2.964 0.375 - 541.7 1 2 0 -0.002 14 0 0 0 2.76E+07 2.37E+07 - - - 5.6078 0.9999 221125_WJC_METTL3_EV_vs_WT_F04.13577.13577.2 0.000873 20-Dec K.AQIWDTAGQER[166.11].Y "sp|Q15907|RB11B_HUMAN,sp|P62491|RB11A_HUMAN,tr|H3BMH2|H3BMH2_HUMAN,tr|H3BSC1|H3BSC1_HUMAN" 4 1283.6134 1.1 47668 13577 2 1283.612266 642.814 Ras-related protein Rab-11B OS=Homo sapiens OX=9606 GN=RAB11B PE=1 SV=4 4.37 2565 - 2.72E+06 - - - -0.871 - 2.345 0.489 - 488.1 1 2 0 -0.0011 11 0 0 0 1.09E+08 9.93E+07 - - - 4.958 0.9983 221125_WJC_METTL3_EV_vs_WT_F04.13580.13580.3 0.000149 Dec-52 K.LNHVAAGLVSPSLK[136.11].S "sp|Q05519|SRS11_HUMAN,tr|Q5T760|Q5T760_HUMAN,tr|Q5T757|Q5T757_HUMAN" 3 1412.8231 0.84 47671 13580 3 1412.828053 471.9483 Serine\arginine-rich splicing factor 11 OS=Homo sapiens OX=9606 GN=SRSF11 PE=1 SV=1 8.76 2565.3 - 1.37E+06 - - - 3.5065 - 2.134 0.326 - 166.8 1 2 0 0.005 14 0 0 0 6.57E+07 7.84E+07 - - - 4.1876 1 221125_WJC_METTL3_EV_vs_WT_F04.13581.13581.3 2.15E-07 16/48 K.VNKPMELYYAPTK.E sp|Q99496|RING2_HUMAN 1 1552.796 1.49 47672 13581 3 1552.796537 518.6059 E3 ubiquitin-protein ligase RING2 OS=Homo sapiens OX=9606 GN=RNF2 PE=1 SV=1 8.4 2565.5 - 860728 - - - 0.3774 - 3.15 0.451 - 307.6 1 2 0 0.0006 13 0 0 0 2.46E+07 1.65E+07 - - - 6.679 0.9998 221125_WJC_METTL3_EV_vs_WT_F04.13584.13584.2 0.000306 24-Nov K.QQVPSGESAILDR[166.11].V "sp|P09874|PARP1_HUMAN,tr|A0A7I2V5E9|A0A7I2V5E9_HUMAN,tr|A0A7I2V625|A0A7I2V625_HUMAN,tr|A0A7I2V3E1|A0A7I2V3E1_HUMAN" 4 1408.7186 1.15 47674 13584 2 1408.717626 705.3666 Poly [ADP-ribose] polymerase 1 OS=Homo sapiens OX=9606 GN=PARP1 PE=1 SV=4 4.37 2565.8 - 9.37E+06 - - - -0.6751 - 2.272 0.455 - 249.3 1 2 0 -0.001 13 0 0 0 2.80E+08 2.43E+08 - - - 4.5076 0.7888 221125_WJC_METTL3_EV_vs_WT_F04.13588.13588.3 0.0237 Nov-40 F.GVISNHLILNK.L "sp|P43243|MATR3_HUMAN,tr|D6RE02|D6RE02_HUMAN,tr|B3KM87|B3KM87_HUMAN,tr|A8MXP9|A8MXP9_HUMAN,tr|D6R991|D6R991_HUMAN,tr|D6RBK5|D6RBK5_HUMAN,tr|A0A0R4J2E8|A0A0R4J2E8_HUMAN,tr|D6RIA2|D6RIA2_HUMAN,tr|H0Y8T4|H0Y8T4_HUMAN,tr|D6REM6|D6REM6_HUMAN,tr|D6RBI2|D6RBI2_HUMAN" 11 1206.7085 1.24 47677 13588 3 1206.706177 403.2434 Matrin-3 OS=Homo sapiens OX=9606 GN=MATR3 PE=1 SV=2 8.76 2566.1 - 3.87E+06 - - - -1.8894 - 1.69 0.268 - 98.8 1 1 0 -0.0023 11 0 0 0 3.06E+08 2.47E+08 - - - 3.018 1 221125_WJC_METTL3_EV_vs_WT_F04.13589.13589.2 1.04E-07 24-Dec K.EYLEAEENGDLER[166.11].M "sp|Q96DF8|ESS2_HUMAN,tr|F8WEF8|F8WEF8_HUMAN" 2 1575.6928 2.34 47678 13589 2 1575.686078 788.8537 Splicing factor ESS-2 homolog OS=Homo sapiens OX=9606 GN=ESS2 PE=1 SV=1 3.83 2566.3 - 1.22E+06 - - - -4.2762 - 2.583 0.678 - 562 1 2 0 -0.0067 13 0 0 0 3.40E+07 1.46E+07 - - - 6.4821 0.9999 221125_WJC_METTL3_EV_vs_WT_F04.13590.13590.2 6.74E-05 14/24 R.QTEVLLQPNPSAR.V "sp|Q9NR46|SHLB2_HUMAN,tr|F8WFB9|F8WFB9_HUMAN,tr|B7ZC39|B7ZC39_HUMAN,tr|B7ZC38|B7ZC38_HUMAN" 4 1451.7732 2.1 47679 13590 2 1451.77454 726.8939 Endophilin-B2 OS=Homo sapiens OX=9606 GN=SH3GLB2 PE=1 SV=1 6 2566.4 - 1.10E+06 - - - 0.8941 - 2.627 0.5 - 627 1 2 0 0.0013 13 0 0 0 2.36E+07 1.12E+07 - - - 5.2125 0.9993 221125_WJC_METTL3_EV_vs_WT_F04.13591.13591.2 0.0115 18-Oct R.HITIFSPEGR.L "sp|P60900|PSA6_HUMAN,tr|G3V5Z7|G3V5Z7_HUMAN,tr|G3V295|G3V295_HUMAN,tr|G3V2S7|G3V2S7_HUMAN,tr|G3V3I1|G3V3I1_HUMAN,tr|G3V3U4|G3V3U4_HUMAN,tr|G3V4S5|G3V4S5_HUMAN" 7 1155.6037 0.4 47680 13591 2 1155.604261 578.8091 Proteasome subunit alpha type-6 OS=Homo sapiens OX=9606 GN=PSMA6 PE=1 SV=1 6.75 2566.5 - 925169 - - - 0.5227 - 1.673 0.313 - 282.5 1 2 0 0.0006 10 0 0 0 1.78E+07 4.41E+07 - - - 2.7891 0.9984 221125_WJC_METTL3_EV_vs_WT_F04.13592.13592.2 0.0266 18-Nov R.HITIFSPEGR[166.11].L "sp|P60900|PSA6_HUMAN,tr|G3V5Z7|G3V5Z7_HUMAN,tr|G3V295|G3V295_HUMAN,tr|G3V2S7|G3V2S7_HUMAN,tr|G3V3I1|G3V3I1_HUMAN,tr|G3V3U4|G3V3U4_HUMAN,tr|G3V4S5|G3V4S5_HUMAN" 7 1165.6119 0.51 47681 13592 2 1165.609219 583.8132 Proteasome subunit alpha type-6 OS=Homo sapiens OX=9606 GN=PSMA6 PE=1 SV=1 6.75 2566.7 - 831764 - - - -2.3232 - 2.017 0.253 - 401.1 1 2 0 -0.0027 10 0 0 0 1.76E+07 3.47E+07 - - - 2.8672 0.9791 221125_WJC_METTL3_EV_vs_WT_F04.13594.13594.2 0.00505 16-Sep R.VITIMQNPR.Q sp|P62269|RS18_HUMAN 1 1070.5907 1.57 47683 13594 2 1070.590575 536.3026 40S ribosomal protein S18 OS=Homo sapiens OX=9606 GN=RPS18 PE=1 SV=3 9.72 2566.9 - 627864 - - - -0.0701 - 1.29 0.047 - 224.1 1 2 0 -0.0001 9 0 0 0 9.64E+06 6.15E+06 - - - 0.1248 0.9997 221125_WJC_METTL3_EV_vs_WT_F04.13595.13595.3 0.0146 Nov-36 R.HITIFSPEGR.L "sp|P60900|PSA6_HUMAN,tr|G3V5Z7|G3V5Z7_HUMAN,tr|G3V295|G3V295_HUMAN,tr|G3V2S7|G3V2S7_HUMAN,tr|G3V3I1|G3V3I1_HUMAN,tr|G3V3U4|G3V3U4_HUMAN,tr|G3V4S5|G3V4S5_HUMAN" 7 1155.6037 0.37 47684 13595 3 1155.601587 386.2085 Proteasome subunit alpha type-6 OS=Homo sapiens OX=9606 GN=PSMA6 PE=1 SV=1 6.75 2567.1 - 451953 - - - -1.7913 - 2.435 0.3 - 163.5 1 2 0 -0.0021 10 0 0 0 1.21E+07 3.28E+07 - - - 4.4832 0.8515 221125_WJC_METTL3_EV_vs_WT_F04.13596.13596.3 0.461 Sep-56 R.VELAEEDDGEKIAIK.L "sp|Q9H4A3|WNK1_HUMAN,tr|F5GWT4|F5GWT4_HUMAN" 2 1657.841 6.85 47685 13596 3 1657.840931 553.621 Serine\threonine-protein kinase WNK1 OS=Homo sapiens OX=9606 GN=WNK1 PE=1 SV=2 4.08 2567.2 - 370205 - - - -0.07 - 1.492 0.143 - 52.4 2 2 1 -0.0001 15 0 0 0 4.11E+06 6.00E+05 - - - 1.039 1 221125_WJC_METTL3_EV_vs_WT_F04.13599.13599.3 2.87E-08 18/56 R.STSHK[136.11]PDEIYGMIER[166.11].L sp|Q86U44|MTA70_HUMAN 1 1779.8581 0.03 47686 13599 3 1779.854339 594.2933 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 5.42 2567.6 - 2.22E+06 - - - -2.0872 - 3.186 0.558 - 391.6 1 2 0 -0.0037 15 0 0 0 1.76E+06 6.21E+07 - - - 7.7838 0.9796 221125_WJC_METTL3_EV_vs_WT_F04.13600.13600.2 0.00152 20-Nov F.GVISNHLILNK[136.11].L "sp|P43243|MATR3_HUMAN,tr|D6RE02|D6RE02_HUMAN,tr|B3KM87|B3KM87_HUMAN,tr|A8MXP9|A8MXP9_HUMAN,tr|D6R991|D6R991_HUMAN,tr|D6RBK5|D6RBK5_HUMAN,tr|A0A0R4J2E8|A0A0R4J2E8_HUMAN,tr|D6RIA2|D6RIA2_HUMAN,tr|H0Y8T4|H0Y8T4_HUMAN,tr|D6REM6|D6REM6_HUMAN,tr|D6RBI2|D6RBI2_HUMAN" 11 1214.7227 1.28 47687 13600 2 1214.721896 608.3686 Matrin-3 OS=Homo sapiens OX=9606 GN=MATR3 PE=1 SV=2 8.76 2567.6 - 1.98E+06 - - - -0.6265 - 2.023 0.342 - 303.3 1 1 0 -0.0008 11 0 0 0 8.33E+07 6.49E+07 - - - 3.4728 0.9857 221125_WJC_METTL3_EV_vs_WT_F04.13601.13601.2 0.233 16-Dec V.ISNHLILNK[136.11].L "sp|P43243|MATR3_HUMAN,tr|D6RE02|D6RE02_HUMAN,tr|B3KM87|B3KM87_HUMAN,tr|A8MXP9|A8MXP9_HUMAN,tr|D6R991|D6R991_HUMAN,tr|D6RBK5|D6RBK5_HUMAN,tr|A0A0R4J2E8|A0A0R4J2E8_HUMAN,tr|D6RIA2|D6RIA2_HUMAN,tr|H0Y8T4|H0Y8T4_HUMAN,tr|D6REM6|D6REM6_HUMAN,tr|D6RBI2|D6RBI2_HUMAN" 11 1058.6328 1.3 47688 13601 2 1058.631803 530.3237 Matrin-3 OS=Homo sapiens OX=9606 GN=MATR3 PE=1 SV=2 8.76 2567.8 - 1.32E+06 - - - -0.9219 - 2.616 0.299 - 495.5 1 1 0 -0.001 9 0 0 0 5.72E+07 4.41E+07 - - - 4.0312 1 221125_WJC_METTL3_EV_vs_WT_F04.13603.13603.3 0.000279 15/48 K.VNK[136.11]PMELYYAPTK[136.11].E sp|Q99496|RING2_HUMAN 1 1568.8244 1.49 47690 13603 3 1568.824179 523.9487 E3 ubiquitin-protein ligase RING2 OS=Homo sapiens OX=9606 GN=RNF2 PE=1 SV=1 8.4 2568 - 1.19E+06 - - - -0.1096 - 2.695 0.555 - 266.6 1 2 0 -0.0002 13 0 0 0 2.46E+07 1.65E+07 - - - 7.4156 0.9999 221125_WJC_METTL3_EV_vs_WT_F04.13604.13604.2 2.03E-06 15/24 R.QTEVLLQPNPSAR[166.11].V "sp|Q9NR46|SHLB2_HUMAN,tr|F8WFB9|F8WFB9_HUMAN,tr|B7ZC39|B7ZC39_HUMAN,tr|B7ZC38|B7ZC38_HUMAN" 4 1461.7815 2.09 47691 13604 2 1461.782784 731.898 Endophilin-B2 OS=Homo sapiens OX=9606 GN=SH3GLB2 PE=1 SV=1 6 2568.1 - 974658 - - - 0.8702 - 2.735 0.451 - 762.2 1 2 0 0.0013 13 0 0 0 2.34E+07 1.12E+07 - - - 4.954 0.9935 221125_WJC_METTL3_EV_vs_WT_F04.13606.13606.2 0.0842 18-Aug K.DYTVTQVPPK.H "sp|Q8N5Z5|KCD17_HUMAN,tr|A0A087WX35|A0A087WX35_HUMAN,tr|H0Y731|H0Y731_HUMAN" 3 1146.5921 2.58 47693 13606 2 1146.589529 574.3033 BTB\POZ domain-containing protein KCTD17 OS=Homo sapiens OX=9606 GN=KCTD17 PE=1 SV=3 5.83 2568.4 - 657040 - - - -2.2336 - 1.362 0.229 - 199.2 1 2 0 -0.0026 10 0 0 0 1.48E+07 5.76E+06 - - - 1.594 0.9993 221125_WJC_METTL3_EV_vs_WT_F04.13607.13607.2 0.000542 20-Aug K.ETTIDGEELVK.L "sp|P52732|KIF11_HUMAN,tr|A0A7I2YQY4|A0A7I2YQY4_HUMAN,tr|A0A7I2V3A9|A0A7I2V3A9_HUMAN,tr|A0A7I2V3V3|A0A7I2V3V3_HUMAN" 4 1232.6136 999 47694 13607 2 1232.610986 617.3141 Kinesin-like protein KIF11 OS=Homo sapiens OX=9606 GN=KIF11 PE=1 SV=2 4 2568.5 - 580763 - - - -2.1312 - 1.729 0.421 - 163.6 1 2 0 -0.0026 11 0 0 0 7.02E+06 0.00E+00 - - - 3.6309 0.978 221125_WJC_METTL3_EV_vs_WT_F04.13612.13612.4 0.0383 13/84 R.STSHK[136.11]PDEIYGMIER[166.11].L sp|Q86U44|MTA70_HUMAN 1 1779.8581 0.001 47697 13612 4 1779.856488 445.9718 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 5.42 2569.2 - 2.50E+06 - - - -0.8798 - 1.545 0.174 - 91.1 1 2 0 -0.0016 15 0 0 0 0.00E+00 3.04E+07 - - - 0.8957 0.9834 221125_WJC_METTL3_EV_vs_WT_F04.13613.13613.2 0.00474 16-Nov V.ISNHLILNK.L "sp|P43243|MATR3_HUMAN,tr|D6RE02|D6RE02_HUMAN,tr|B3KM87|B3KM87_HUMAN,tr|A8MXP9|A8MXP9_HUMAN,tr|D6R991|D6R991_HUMAN,tr|D6RBK5|D6RBK5_HUMAN,tr|A0A0R4J2E8|A0A0R4J2E8_HUMAN,tr|D6RIA2|D6RIA2_HUMAN,tr|H0Y8T4|H0Y8T4_HUMAN,tr|D6REM6|D6REM6_HUMAN,tr|D6RBI2|D6RBI2_HUMAN" 11 1050.6186 1.3 47698 13613 2 1050.617752 526.3166 Matrin-3 OS=Homo sapiens OX=9606 GN=MATR3 PE=1 SV=2 8.76 2569.2 - 2.44E+06 - - - -0.7872 - 2.343 0.307 - 440.8 1 1 0 -0.0008 9 0 0 0 5.72E+07 4.41E+07 - - - 3.7715 0.9999 221125_WJC_METTL3_EV_vs_WT_F04.13614.13614.3 0.000929 Sep-36 K.NYGFVHIEDK[136.11].T "sp|Q9BWF3|RBM4_HUMAN,sp|Q9BQ04|RBM4B_HUMAN,tr|E9PM61|E9PM61_HUMAN,tr|D6R9K7|D6R9K7_HUMAN,tr|J3QRR5|J3QRR5_HUMAN,tr|E9PB51|E9PB51_HUMAN,tr|U3KQD5|U3KQD5_HUMAN,tr|E9PLB0|E9PLB0_HUMAN" 8 1228.5968 1.67 47699 13614 3 1228.595582 410.5395 RNA-binding protein 4 OS=Homo sapiens OX=9606 GN=RBM4 PE=1 SV=1 5.32 2569.3 - 9.39E+06 - - - -0.9816 - 1.973 0.422 - 114.4 1 2 0 -0.0012 10 0 0 0 7.13E+08 4.26E+08 - - - 5.2291 0.9998 221125_WJC_METTL3_EV_vs_WT_F04.13615.13615.2 4.61E-05 18-Sep K.NYGFVHIEDK[136.11].T "sp|Q9BWF3|RBM4_HUMAN,sp|Q9BQ04|RBM4B_HUMAN,tr|E9PM61|E9PM61_HUMAN,tr|D6R9K7|D6R9K7_HUMAN,tr|J3QRR5|J3QRR5_HUMAN,tr|E9PB51|E9PB51_HUMAN,tr|U3KQD5|U3KQD5_HUMAN,tr|E9PLB0|E9PLB0_HUMAN" 8 1228.5968 1.52 47700 13615 2 1228.596362 615.3057 RNA-binding protein 4 OS=Homo sapiens OX=9606 GN=RBM4 PE=1 SV=1 5.32 2569.4 - 1.55E+06 - - - -0.3467 - 1.726 0.488 - 245.3 1 2 0 -0.0004 10 0 0 0 1.50E+08 9.86E+07 - - - 4.1687 0.9992 221125_WJC_METTL3_EV_vs_WT_F04.13616.13616.3 0.0151 Jul-40 R.DLHPDLEGQLK[136.11].E sp|Q9NYU2|UGGG1_HUMAN 1 1271.6601 0.09 47701 13616 3 1271.659563 424.894 UDP-glucose:glycoprotein glucosyltransferase 1 OS=Homo sapiens OX=9606 GN=UGGT1 PE=1 SV=3 4.54 2569.4 - 1.26E+06 - - - -0.4349 - 1.628 0.318 - 101.9 1 2 0 -0.0006 11 0 0 0 1.25E+06 1.40E+07 - - - 3.4697 0.9784 221125_WJC_METTL3_EV_vs_WT_F04.13618.13618.2 0.0075 16/26 L.ALAAAPSSNGSPWR[166.11].L "sp|Q9H2W6|RM46_HUMAN,tr|H0YN64|H0YN64_HUMAN,tr|A0A087WT90|A0A087WT90_HUMAN" 3 1393.6978 1.56 47703 13618 2 1393.695726 697.8562 "39S ribosomal protein L46, mitochondrial OS=Homo sapiens OX=9606 GN=MRPL46 PE=1 SV=1" 9.79 2569.6 - 842233 - - - -1.4752 - 2.514 0.337 - 738.1 1 1 0 -0.0021 14 0 0 0 1.17E+07 7.53E+06 - - - 3.8428 0.9998 221125_WJC_METTL3_EV_vs_WT_F04.13620.13620.3 5.01E-06 16/48 K.VVSK[136.11]EESIVSSLR[166.11].L "sp|Q9NP61|ARFG3_HUMAN,tr|H0Y6A0|H0Y6A0_HUMAN" 2 1449.8158 1.01 47705 13620 3 1449.816082 484.2792 ADP-ribosylation factor GTPase-activating protein 3 OS=Homo sapiens OX=9606 GN=ARFGAP3 PE=1 SV=1 6.11 2569.9 - 738838 - - - 0.209 - 2.816 0.428 - 355.6 1 2 1 0.0003 13 0 0 0 7.19E+07 7.12E+07 - - - 6.1187 0.9999 221125_WJC_METTL3_EV_vs_WT_F04.13624.13624.2 2.09E-07 26-Oct K.AGPEYGQGMNPISR[166.11].L "sp|Q9NUL3|STAU2_HUMAN,tr|E5RJN7|E5RJN7_HUMAN,tr|E7EVJ4|E7EVJ4_HUMAN,tr|E7EVI1|E7EVI1_HUMAN,tr|E7EPX0|E7EPX0_HUMAN" 5 1485.691 0.001 47709 13624 2 1485.691402 743.8528 Double-stranded RNA-binding protein Staufen homolog 2 OS=Homo sapiens OX=9606 GN=STAU2 PE=1 SV=2 6.05 2570.4 - 466956 - - - 0.2827 - 2.114 0.601 - 269.3 1 2 0 0.0004 14 0 0 0 0.00E+00 7.66E+06 - - - 5.3584 1 221125_WJC_METTL3_EV_vs_WT_F04.13625.13625.2 2.17E-09 16/32 R.GLGVGFGSGGGSSSSVK.F sp|P13647|K2C5_HUMAN 1 1438.7052 251.96 47710 13625 2 1438.702454 720.3599 "Keratin, type II cytoskeletal 5 OS=Homo sapiens OX=9606 GN=KRT5 PE=1 SV=3" 8.75 2570.5 - 445560 - - - -1.924 - 3.089 0.619 - 838.3 1 2 0 -0.0028 17 0 0 0 3.43E+08 1.36E+06 - - - 6.3849 0.9994 221125_WJC_METTL3_EV_vs_WT_F04.13627.13627.2 1.92E-06 22-Nov R.EAGEDEEGFLSK[136.11].L sp|Q96EY1|DNJA3_HUMAN 1 1317.5816 1.48 47712 13627 2 1317.585515 659.7981 "DnaJ homolog subfamily A member 3, mitochondrial OS=Homo sapiens OX=9606 GN=DNAJA3 PE=1 SV=2" 3.91 2570.8 - 304482 - - - 2.9782 - 1.888 0.539 - 206.4 1 2 0 0.0039 12 0 0 0 5.21E+06 3.53E+06 - - - 4.693 0.9919 221125_WJC_METTL3_EV_vs_WT_F04.13633.13633.2 0.000603 14/20 F.GVISNHLILNK.L "sp|P43243|MATR3_HUMAN,tr|D6RE02|D6RE02_HUMAN,tr|B3KM87|B3KM87_HUMAN,tr|A8MXP9|A8MXP9_HUMAN,tr|D6R991|D6R991_HUMAN,tr|D6RBK5|D6RBK5_HUMAN,tr|A0A0R4J2E8|A0A0R4J2E8_HUMAN,tr|D6RIA2|D6RIA2_HUMAN,tr|H0Y8T4|H0Y8T4_HUMAN,tr|D6REM6|D6REM6_HUMAN,tr|D6RBI2|D6RBI2_HUMAN" 11 1206.7085 1.28 47716 13633 2 1206.708379 604.3615 Matrin-3 OS=Homo sapiens OX=9606 GN=MATR3 PE=1 SV=2 8.76 2571.4 - 5.92E+06 - - - -0.0646 - 2.642 0.403 - 558.6 1 1 0 -0.0001 11 0 0 0 8.33E+07 6.49E+07 - - - 4.6458 0.971 221125_WJC_METTL3_EV_vs_WT_F04.13634.13634.2 0.707 14-Nov L.SNHLILNK[136.11].L "sp|P43243|MATR3_HUMAN,tr|D6RE02|D6RE02_HUMAN,tr|B3KM87|B3KM87_HUMAN,tr|A8MXP9|A8MXP9_HUMAN,tr|D6R991|D6R991_HUMAN,tr|D6RBK5|D6RBK5_HUMAN,tr|A0A0R4J2E8|A0A0R4J2E8_HUMAN,tr|D6RIA2|D6RIA2_HUMAN,tr|H0Y8T4|H0Y8T4_HUMAN,tr|D6REM6|D6REM6_HUMAN,tr|D6RBI2|D6RBI2_HUMAN" 11 945.5487 1.54 47717 13634 2 945.549748 473.7816 Matrin-3 OS=Homo sapiens OX=9606 GN=MATR3 PE=1 SV=2 8.49 2571.5 - 1.06E+06 - - - 1.0925 - 1.93 0.318 - 527 1 1 0 0.001 8 0 0 0 1.75E+07 1.14E+07 - - - 3.3725 0.9998 221125_WJC_METTL3_EV_vs_WT_F04.13635.13635.3 0.0327 13/40 R.EQMEAEIAHLK.Q sp|Q86UP2|KTN1_HUMAN 1 1297.6336 2.2 47718 13635 3 1297.633525 433.5518 Kinectin OS=Homo sapiens OX=9606 GN=KTN1 PE=1 SV=1 4.75 2571.6 - 974075 - - - -0.0863 - 2.166 0.352 - 286.7 1 2 0 -0.0001 11 0 0 0 1.22E+07 5.55E+06 - - - 4.66 0.9994 221125_WJC_METTL3_EV_vs_WT_F04.13638.13638.2 2.02E-05 22-Sep R.AQPSVSLGAPYR.G sp|Q96PK6|RBM14_HUMAN 1 1244.6513 1.88 47721 13638 2 1244.650361 623.3329 RNA-binding protein 14 OS=Homo sapiens OX=9606 GN=RBM14 PE=1 SV=2 8.79 2572 - 706672 - - - -0.7834 - 2.137 0.263 - 284.6 1 2 0 -0.001 12 0 0 0 7.40E+08 3.95E+08 - - - 2.9813 1 221125_WJC_METTL3_EV_vs_WT_F04.13639.13639.2 5.27E-10 15/24 R.NEQDAYAINSYTR[166.11].S "sp|P24752|THIL_HUMAN,tr|A0A5F9ZHJ7|A0A5F9ZHJ7_HUMAN,tr|A0A5F9ZHD4|A0A5F9ZHD4_HUMAN,tr|A0A5F9ZHJ0|A0A5F9ZHJ0_HUMAN,tr|A0A5F9ZHL1|A0A5F9ZHL1_HUMAN,tr|A0A5F9ZI66|A0A5F9ZI66_HUMAN" 6 1553.6986 0.33 47722 13639 2 1553.69844 777.8566 "Acetyl-CoA acetyltransferase, mitochondrial OS=Homo sapiens OX=9606 GN=ACAT1 PE=1 SV=1" 4.37 2572.1 - 643593 - - - -0.0837 - 3.11 0.689 - 1103 1 2 0 -0.0001 13 0 0 0 1.37E+07 4.11E+07 - - - 7.042 0.9918 221125_WJC_METTL3_EV_vs_WT_F04.13641.13641.2 0.000188 16-Dec N.YGFVHIEDK.T "sp|Q9BWF3|RBM4_HUMAN,sp|Q9BQ04|RBM4B_HUMAN,tr|E9PM61|E9PM61_HUMAN,tr|D6R9K7|D6R9K7_HUMAN,tr|J3QRR5|J3QRR5_HUMAN,tr|E9PB51|E9PB51_HUMAN,tr|U3KQD5|U3KQD5_HUMAN,tr|E9PLB0|E9PLB0_HUMAN" 8 1106.5397 0.72 47724 13641 2 1106.537923 554.2771 RNA-binding protein 4 OS=Homo sapiens OX=9606 GN=RBM4 PE=1 SV=1 5.32 2572.4 - 542687 - - - -1.5698 - 2.587 0.515 - 458.1 1 1 0 -0.0017 9 0 0 0 1.26E+07 1.75E+07 - - - 5.5941 0.9997 221125_WJC_METTL3_EV_vs_WT_F04.13642.13642.2 2.80E-06 22-Nov R.AQPSVSLGAPYR[166.11].G sp|Q96PK6|RBM14_HUMAN 1 1254.6596 1.88 47725 13642 2 1254.658646 628.3371 RNA-binding protein 14 OS=Homo sapiens OX=9606 GN=RBM14 PE=1 SV=2 8.79 2572.5 - 538345 - - - -0.7651 - 2.282 0.323 - 473.5 1 2 0 -0.001 12 0 0 0 7.40E+08 3.95E+08 - - - 3.5972 0.9989 221125_WJC_METTL3_EV_vs_WT_F04.13647.13647.2 0.0713 20-Oct K.VQVALGNISSK[136.11].R "sp|O75935|DCTN3_HUMAN,tr|X6RA56|X6RA56_HUMAN,tr|X6RLR1|X6RLR1_HUMAN,tr|A0A0A0MRV8|A0A0A0MRV8_HUMAN,tr|X6RCK5|X6RCK5_HUMAN" 5 1122.6488 3.34 47730 13647 2 1122.648049 562.3317 Dynactin subunit 3 OS=Homo sapiens OX=9606 GN=DCTN3 PE=1 SV=1 8.72 2573.2 - 280138 - - - -0.6894 - 1.989 0.196 - 309.3 1 2 0 -0.0008 11 0 0 0 2.74E+07 8.19E+06 - - - 2.3486 0.9998 221125_WJC_METTL3_EV_vs_WT_F04.13650.13650.3 0.0717 14/44 K.IVVELPHSVNSK.L sp|Q8N4Q0|PTGR3_HUMAN 1 1320.7402 1.05 47732 13650 3 1320.740033 441.254 Prostaglandin reductase 3 OS=Homo sapiens OX=9606 GN=ZADH2 PE=1 SV=1 6.75 2573.5 - 1.33E+06 - - - -0.0893 - 2.374 0.31 - 331.7 1 2 0 -0.0001 12 0 0 0 1.37E+07 1.31E+07 - - - 4.3926 0.9997 221125_WJC_METTL3_EV_vs_WT_F04.13651.13651.2 0.00073 22-Oct R.EGIVTATEQEVK[136.11].E "sp|Q12931|TRAP1_HUMAN,tr|I3L0K7|I3L0K7_HUMAN" 2 1310.6809 1.74 47733 13651 2 1310.680672 656.3477 "Heat shock protein 75 kDa, mitochondrial OS=Homo sapiens OX=9606 GN=TRAP1 PE=1 SV=3" 4.25 2573.6 - 610185 - - - -0.1823 - 2.062 0.335 - 369.7 1 2 0 -0.0002 12 0 0 0 2.67E+07 1.53E+07 - - - 3.4194 0.9995 221125_WJC_METTL3_EV_vs_WT_F04.13652.13652.2 0.0221 20-Dec K.VQVALGNISSK.R "sp|O75935|DCTN3_HUMAN,tr|X6RA56|X6RA56_HUMAN,tr|X6RLR1|X6RLR1_HUMAN,tr|A0A0A0MRV8|A0A0A0MRV8_HUMAN,tr|X6RCK5|X6RCK5_HUMAN" 5 1114.6346 3.39 47734 13652 2 1114.632462 558.3246 Dynactin subunit 3 OS=Homo sapiens OX=9606 GN=DCTN3 PE=1 SV=1 8.72 2573.7 - 1.30E+06 - - - -1.9388 - 2.173 0.355 - 465.1 1 2 0 -0.0022 11 0 0 0 2.78E+07 8.19E+06 - - - 3.7619 0.9997 221125_WJC_METTL3_EV_vs_WT_F04.13653.13653.2 0.00504 20-Nov K.RISGLIYEETR.G sp|P62805|H4_HUMAN 1 1335.7147 1.25 47735 13653 2 1335.714384 668.8646 Histone H4 OS=Homo sapiens OX=9606 GN=H4C1 PE=1 SV=2 6.14 2573.9 - 1.11E+06 - - - -0.2096 - 1.977 0.354 - 172.9 1 2 0 -0.0003 11 0 0 0 1.50E+07 1.20E+07 - - - 3.4994 0.9997 221125_WJC_METTL3_EV_vs_WT_F04.13655.13655.2 5.50E-08 22-Dec K.TC[160.03]AAQLVSYPGK.N sp|Q09161|NCBP1_HUMAN 1 1293.6387 0.31 47737 13655 2 1293.642101 647.8266 Nuclear cap-binding protein subunit 1 OS=Homo sapiens OX=9606 GN=NCBP1 PE=1 SV=1 7.86 2574.1 - 599490 - - - 2.612 - 2.115 0.592 - 420.2 1 2 0 0.0034 12 0 0 0 6.77E+06 2.20E+07 - - - 5.3833 0.9898 221125_WJC_METTL3_EV_vs_WT_F04.13657.13657.2 8.22E-05 13/26 L.ALAAAPSSNGSPWR.L "sp|Q9H2W6|RM46_HUMAN,tr|H0YN64|H0YN64_HUMAN,tr|A0A087WT90|A0A087WT90_HUMAN" 3 1383.6895 1.61 47739 13657 2 1383.691495 692.852 "39S ribosomal protein L46, mitochondrial OS=Homo sapiens OX=9606 GN=MRPL46 PE=1 SV=1" 9.79 2574.3 - 384121 - - - 1.4331 - 2.775 0.481 - 397.5 1 1 0 0.002 14 0 0 0 1.23E+07 7.65E+06 - - - 5.1543 0.9998 221125_WJC_METTL3_EV_vs_WT_F04.13666.13666.2 0.0885 20-Nov K.R[166.11]ISGLIYEETR[166.11].G sp|P62805|H4_HUMAN 1 1355.7312 1.25 47746 13666 2 1355.732122 678.8729 Histone H4 OS=Homo sapiens OX=9606 GN=H4C1 PE=1 SV=2 6.14 2575.4 - 564761 - - - 0.6771 - 2.455 0.363 - 189.4 1 2 0 0.0009 11 0 0 0 1.50E+07 1.20E+07 - - - 4.1515 0.9998 221125_WJC_METTL3_EV_vs_WT_F04.13668.13668.2 7.19E-05 24-Nov R.SWQGTADGGMMDR[166.11].D sp|Q15424|SAFB1_HUMAN 1 1420.5739 0.33 47748 13668 2 1420.57156 711.2942 Scaffold attachment factor B1 OS=Homo sapiens OX=9606 GN=SAFB PE=1 SV=4 4.21 2575.7 - 385071 - - - -1.65 - 2.083 0.571 - 385.7 1 2 0 -0.0023 13 0 0 0 1.39E+06 4.22E+06 - - - 5.141 1 221125_WJC_METTL3_EV_vs_WT_F04.13671.13671.2 7.60E-08 16/28 R.VSLAGAC[160.03]GVGGYGSR.S "sp|P13647|K2C5_HUMAN,tr|F8VV57|F8VV57_HUMAN" 2 1409.6721 999 47750 13671 2 1409.670873 705.8434 "Keratin, type II cytoskeletal 5 OS=Homo sapiens OX=9606 GN=KRT5 PE=1 SV=3" 8.19 2576.1 - 3.60E+07 - - - -0.9045 - 2.84 0.612 - 854.1 1 2 0 -0.0013 15 0 0 0 5.70E+08 0.00E+00 - - - 6.1271 0.9844 221125_WJC_METTL3_EV_vs_WT_F04.13675.13675.3 0.386 Aug-40 K.R[166.11]ISGLIYEETR[166.11].G sp|P62805|H4_HUMAN 1 1355.7312 1.18 47753 13675 3 1355.729283 452.9177 Histone H4 OS=Homo sapiens OX=9606 GN=H4C1 PE=1 SV=2 6.14 2576.5 - 1.15E+06 - - - -1.4169 - 1.635 0.155 - 99.7 1 2 0 -0.0019 11 0 0 0 3.41E+07 2.88E+07 - - - 1.6642 1 221125_WJC_METTL3_EV_vs_WT_F04.13676.13676.2 2.41E-10 18/36 R.GLGAGAGAGEESPATSLPR[166.11].M sp|O15173|PGRC2_HUMAN 1 1706.8463 1.53 47754 13676 2 1706.84576 854.4304 Membrane-associated progesterone receptor component 2 OS=Homo sapiens OX=9606 GN=PGRMC2 PE=1 SV=1 4.53 2576.6 - 326100 - - - -0.3146 - 3.353 0.657 - 945.5 1 2 0 -0.0005 19 0 0 0 1.60E+07 1.05E+07 - - - 6.8679 0.7985 221125_WJC_METTL3_EV_vs_WT_F04.13677.13677.2 3.49 18-Jul R.NMDSMPELQK.L sp|Q92900|RENT1_HUMAN 1 1191.5264 1.1 47755 13677 2 1191.523995 596.7705 Regulator of nonsense transcripts 1 OS=Homo sapiens OX=9606 GN=UPF1 PE=1 SV=2 4.37 2576.8 - 245052 - - - -2.0142 - 0.793 0.111 - 46.7 2 2 0 -0.0024 10 0 0 0 3.14E+06 2.85E+06 - - - -0.9218 0.9949 221125_WJC_METTL3_EV_vs_WT_F04.13683.13683.3 0.0728 Aug-40 K.RISGLIYEETR.G sp|P62805|H4_HUMAN 1 1335.7147 1.18 47759 13683 3 1335.713706 446.2455 Histone H4 OS=Homo sapiens OX=9606 GN=H4C1 PE=1 SV=2 6.14 2577.5 - 1.29E+06 - - - -0.7172 - 1.575 0.214 - 105.3 1 2 0 -0.001 11 0 0 0 3.41E+07 2.88E+07 - - - 2.2161 0.9979 221125_WJC_METTL3_EV_vs_WT_F04.13686.13686.3 0.114 Nov-44 K.VFDGIPPPYDKK.K "sp|P40429|RL13A_HUMAN,sp|Q6NVV1|R13P3_HUMAN,tr|M0QYS1|M0QYS1_HUMAN,tr|Q8J015|Q8J015_HUMAN,tr|A0A7I2V2L9|A0A7I2V2L9_HUMAN,tr|A0A7I2V5L3|A0A7I2V5L3_HUMAN" 6 1374.7184 1.37 47762 13686 3 1374.716874 459.2467 60S ribosomal protein L13a OS=Homo sapiens OX=9606 GN=RPL13A PE=1 SV=2 5.93 2577.8 - 595048 - - - -1.0759 - 2.052 0.204 - 151.2 1 2 0 -0.0015 12 0 0 0 3.32E+07 2.42E+07 - - - 2.8064 1 221125_WJC_METTL3_EV_vs_WT_F04.13687.13687.4 2.48E-10 22/114 K.R[166.11]GLLQDDAHPTLVTYADHSK[136.11].L "sp|Q86U44|MTA70_HUMAN,tr|F5H6D8|F5H6D8_HUMAN,tr|H0YFV6|H0YFV6_HUMAN,tr|B4DTN4|B4DTN4_HUMAN" 4 2254.1461 0.001 47763 13687 4 2254.142879 564.5438 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 5.99 2577.9 - 557800 - - - -1.4356 - 3.637 0.569 - 218.5 1 2 0 -0.0032 20 0 0 0 0.00E+00 7.64E+06 - - - 4.6093 0.9933 221125_WJC_METTL3_EV_vs_WT_F04.13689.13689.3 0.0719 Sep-44 K.SHGLLVQQALPK.A "sp|Q9H0P0|5NT3A_HUMAN,tr|B9A035|B9A035_HUMAN,tr|X6RM59|X6RM59_HUMAN" 3 1289.7456 1.57 47765 13689 3 1289.742438 430.9225 Cytosolic 5'-nucleotidase 3A OS=Homo sapiens OX=9606 GN=NT5C3A PE=1 SV=3 8.49 2578.2 - 309294 - - - -2.4292 - 1.668 0.239 - 82.6 1 2 0 -0.0031 12 0 0 0 3.25E+06 2.07E+06 - - - 2.6219 0.9999 221125_WJC_METTL3_EV_vs_WT_F04.13690.13690.2 2.24E-05 20-Sep R.ENVDTFEASVK.A "sp|Q13523|PRP4B_HUMAN,tr|H0YDJ3|H0YDJ3_HUMAN" 2 1237.5826 1.08 47766 13690 2 1237.581742 619.7986 Serine\threonine-protein kinase PRP4 homolog OS=Homo sapiens OX=9606 GN=PRPF4B PE=1 SV=3 4.14 2578.3 - 251720 - - - -0.7313 - 2.086 0.554 - 386.8 1 2 0 -0.0009 11 0 0 0 1.76E+06 1.63E+06 - - - 5.1216 0.9968 221125_WJC_METTL3_EV_vs_WT_F04.13691.13691.2 0.000571 22-Sep K.SLTSWTNDQGAR[166.11].R "sp|Q7Z2W4|ZCCHV_HUMAN,tr|C9J6P4|C9J6P4_HUMAN,tr|A0A7P0T8C6|A0A7P0T8C6_HUMAN" 3 1344.6298 0.54 47767 13691 2 1344.633788 673.3222 Zinc finger CCCH-type antiviral protein 1 OS=Homo sapiens OX=9606 GN=ZC3HAV1 PE=1 SV=3 5.55 2578.5 - 243807 - - - 2.9941 - 1.689 0.308 - 234.8 1 2 0 0.004 12 0 0 0 3.75E+06 6.92E+06 - - - 2.6937 0.9564 221125_WJC_METTL3_EV_vs_WT_F04.13694.13694.2 0.0116 12-Jul R.K[136.11]IELFGR[166.11].P sp|Q86U44|MTA70_HUMAN 1 879.5297 0.01 47768 13694 2 879.528739 440.7721 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 8.75 2578.9 - 7.56E+06 - - - -1.1017 - 1.664 0.295 - 228.1 1 1 0 -0.001 7 0 0 0 8.21E+06 1.58E+09 - - - 2.8331 0.9999 221125_WJC_METTL3_EV_vs_WT_F04.13696.13696.2 0.000109 13/22 K.NAGVEGSLIVEK.L "sp|P10809|CH60_HUMAN,tr|A0A7I2V2X6|A0A7I2V2X6_HUMAN,tr|A0A7I2YQK6|A0A7I2YQK6_HUMAN,tr|A0A7I2V599|A0A7I2V599_HUMAN" 4 1214.6507 1.34 47770 13696 2 1214.6497 608.3326 "60 kDa heat shock protein, mitochondrial OS=Homo sapiens OX=9606 GN=HSPD1 PE=1 SV=2" 4.53 2579 - 4.03E+06 - - - -0.7961 - 2.621 0.508 - 559.5 1 2 0 -0.001 12 0 0 0 3.32E+08 2.48E+08 - - - 5.3281 0.9999 221125_WJC_METTL3_EV_vs_WT_F04.13698.13698.2 1.46E-05 20-Dec R.EFDELNPSAQR.D "sp|P16615|AT2A2_HUMAN,tr|H7C5W9|H7C5W9_HUMAN" 2 1304.5997 1.64 47772 13698 2 1304.599625 653.3071 Sarcoplasmic\endoplasmic reticulum calcium ATPase 2 OS=Homo sapiens OX=9606 GN=ATP2A2 PE=1 SV=1 4.14 2579.1 - 1.73E+06 - - - -0.0529 - 1.979 0.545 - 515.1 1 2 0 -0.0001 11 0 0 0 1.48E+07 9.03E+06 - - - 4.9129 0.9999 221125_WJC_METTL3_EV_vs_WT_F04.13699.13699.3 6.54E-05 Oct-44 R.TFIAIK[136.11]PDGVQR[166.11].G "sp|P15531|NDKA_HUMAN,sp|P22392|NDKB_HUMAN,tr|Q32Q12|Q32Q12_HUMAN,tr|Q32Q12|Q32Q12_HUMAN,tr|J3KPD9|J3KPD9_HUMAN,tr|F6XY72|F6XY72_HUMAN,tr|E5RHP0|E5RHP0_HUMAN,tr|E7ERL0|E7ERL0_HUMAN,tr|C9K028|C9K028_HUMAN" 9 1361.7786 1.63 47773 13699 3 1361.776593 454.9335 Nucleoside diphosphate kinase A OS=Homo sapiens OX=9606 GN=NME1 PE=1 SV=1 8.41 2579.2 - 1.26E+06 - - - -1.4775 - 2.024 0.458 - 116.1 1 2 0 -0.002 12 0 0 0 1.70E+07 1.04E+07 - - - 5.6001 1 221125_WJC_METTL3_EV_vs_WT_F04.13700.13700.2 3.35E-07 16/24 K.VVSK[136.11]EESIVSSLR[166.11].L "sp|Q9NP61|ARFG3_HUMAN,tr|H0Y6A0|H0Y6A0_HUMAN" 2 1449.8158 1.18 47774 13700 2 1449.815726 725.9152 ADP-ribosylation factor GTPase-activating protein 3 OS=Homo sapiens OX=9606 GN=ARFGAP3 PE=1 SV=1 6.11 2579.3 - 1.02E+06 - - - -0.0366 - 2.726 0.567 - 1021.9 1 2 1 -0.0001 13 0 0 0 1.26E+07 1.07E+07 - - - 5.8027 1 221125_WJC_METTL3_EV_vs_WT_F04.13701.13701.2 2.33E-06 13/20 R.QGVDADINGLR.Q "sp|P35527|K1C9_HUMAN,tr|K7EQQ3|K7EQQ3_HUMAN" 2 1156.5837 999 47775 13701 2 1156.582758 579.2991 "Keratin, type I cytoskeletal 9 OS=Homo sapiens OX=9606 GN=KRT9 PE=1 SV=3" 4.21 2579.4 - 831977 - - - -0.7712 - 2.703 0.579 - 1012.9 1 2 0 -0.0009 11 0 0 0 1.50E+09 0.00E+00 - - - 6.0072 0.839 221125_WJC_METTL3_EV_vs_WT_F04.13706.13706.2 0.397 20-Jun R.EAGPDARR[166.11]C[160.03]WR[166.11].F sp|Q13395|TARB1_HUMAN 1 1392.6584 - 47780 13706 2 1392.654801 697.3365 Probable methyltransferase TARBP1 OS=Homo sapiens OX=9606 GN=TARBP1 PE=1 SV=1 8.35 2580.1 - 436830 - - - -2.5778 - 1.093 0.243 - 91.3 1 2 1 -0.0036 11 0 0 0 - - - - - 1.0752 0.987 221125_WJC_METTL3_EV_vs_WT_F04.13707.13707.3 6.98E-05 Nov-52 A.LILHDDEVTVTEDK.L sp|P05386|RLA1_HUMAN 1 1625.8148 0.69 47781 13707 3 1625.812664 542.9456 60S acidic ribosomal protein P1 OS=Homo sapiens OX=9606 GN=RPLP1 PE=1 SV=1 4.1 2580.2 - 432291 - - - -1.3335 - 2.074 0.418 - 200.7 1 1 0 -0.0022 14 0 0 0 4.96E+06 7.15E+06 - - - 5.1383 0.9919 221125_WJC_METTL3_EV_vs_WT_F04.13708.13708.3 0.0328 Aug-36 K.K[136.11]TEVLMENFR[166.11].R "sp|Q9Y265|RUVB1_HUMAN,tr|E7ETR0|E7ETR0_HUMAN" 2 1283.6663 0.79 47782 13708 3 1283.663661 428.896 RuvB-like 1 OS=Homo sapiens OX=9606 GN=RUVBL1 PE=1 SV=1 6.14 2580.4 - 353621 - - - -2.0387 - 1.443 0.243 - 124.3 1 2 0 -0.0026 10 0 0 0 6.59E+06 8.40E+06 - - - 2.3195 0.9987 221125_WJC_METTL3_EV_vs_WT_F04.13712.13712.3 0.000445 Oct-36 K.NYGFVHIEDK.T "sp|Q9BWF3|RBM4_HUMAN,sp|Q9BQ04|RBM4B_HUMAN,tr|E9PM61|E9PM61_HUMAN,tr|D6R9K7|D6R9K7_HUMAN,tr|J3QRR5|J3QRR5_HUMAN,tr|E9PB51|E9PB51_HUMAN,tr|U3KQD5|U3KQD5_HUMAN,tr|E9PLB0|E9PLB0_HUMAN" 8 1220.5826 1.48 47785 13712 3 1220.581552 407.8681 RNA-binding protein 4 OS=Homo sapiens OX=9606 GN=RBM4 PE=1 SV=1 5.32 2580.8 - 2.08E+07 - - - -0.8488 - 2.013 0.226 - 211.9 1 2 0 -0.001 10 0 0 0 6.27E+08 4.24E+08 - - - 3.1026 0.9999 221125_WJC_METTL3_EV_vs_WT_F04.13714.13714.2 0.000944 22-Dec K.NAGVEGSLIVEK[136.11].L "sp|P10809|CH60_HUMAN,tr|A0A7I2V2X6|A0A7I2V2X6_HUMAN,tr|A0A7I2YQK6|A0A7I2YQK6_HUMAN,tr|A0A7I2V599|A0A7I2V599_HUMAN" 4 1222.6649 1.34 47787 13714 2 1222.665118 612.3397 "60 kDa heat shock protein, mitochondrial OS=Homo sapiens OX=9606 GN=HSPD1 PE=1 SV=2" 4.53 2580.9 - 9.03E+06 - - - 0.2053 - 2.452 0.443 - 423.4 1 2 0 0.0003 12 0 0 0 3.31E+08 2.47E+08 - - - 4.6728 0.9999 221125_WJC_METTL3_EV_vs_WT_F04.13717.13717.3 4.53E-05 15/40 R.KLPVSSLTISR.L "sp|Q92552|RT27_HUMAN,tr|G5EA06|G5EA06_HUMAN,tr|D6RH20|D6RH20_HUMAN,tr|E5RJ73|E5RJ73_HUMAN,tr|D6RJC7|D6RJC7_HUMAN" 5 1199.7238 1.06 47790 13717 3 1199.723276 400.9152 "28S ribosomal protein S27, mitochondrial OS=Homo sapiens OX=9606 GN=MRPS27 PE=1 SV=3" 11 2581.1 - 1.88E+06 - - - -0.4134 - 2.389 0.389 - 326 1 2 0 -0.0005 11 0 0 0 4.08E+07 3.86E+07 - - - 5.3508 1 221125_WJC_METTL3_EV_vs_WT_F04.13718.13718.3 0.00444 16/56 R.LLELGPK[136.11]PEVAQQTR[166.11].K "sp|P53621|COPA_HUMAN,tr|A0A3B3ISC6|A0A3B3ISC6_HUMAN,tr|A0A3B3IS84|A0A3B3IS84_HUMAN,tr|A0A3B3ITI7|A0A3B3ITI7_HUMAN,tr|A0A3B3IT15|A0A3B3IT15_HUMAN" 5 1695.9638 0.09 47791 13718 3 1695.962813 566.3286 Coatomer subunit alpha OS=Homo sapiens OX=9606 GN=COPA PE=1 SV=2 6.14 2581.2 - 1.86E+06 - - - -0.6056 - 2.83 0.472 - 346.7 1 2 0 -0.001 15 0 0 0 4.71E+06 5.20E+07 - - - 6.5165 0.9999 221125_WJC_METTL3_EV_vs_WT_F04.13720.13720.2 1.36E-05 13/20 R.GNNVLYISTQK.R sp|P62312|LSM6_HUMAN 1 1235.651 3.66 47793 13720 2 1235.649315 618.8328 U6 snRNA-associated Sm-like protein LSm6 OS=Homo sapiens OX=9606 GN=LSM6 PE=1 SV=1 8.59 2581.4 - 1.00E+06 - - - -1.3645 - 2.61 0.539 - 1025.9 1 2 0 -0.0017 11 0 0 0 5.77E+07 1.58E+07 - - - 5.6168 0.9996 221125_WJC_METTL3_EV_vs_WT_F04.13721.13721.2 6.46E-07 13/22 K.YGGQPVPNFPSK.L "sp|P21333|FLNA_HUMAN,tr|Q60FE5|Q60FE5_HUMAN" 2 1289.6404 1.18 47794 13721 2 1289.643991 645.8275 Filamin-A OS=Homo sapiens OX=9606 GN=FLNA PE=1 SV=4 8.59 2581.5 - 846628 - - - 2.7558 - 2.18 0.525 - 598.3 1 2 0 0.0036 12 0 0 0 3.56E+07 3.03E+07 - - - 4.9681 1 221125_WJC_METTL3_EV_vs_WT_F04.13722.13722.2 4.31E-07 13/22 K.SEVSSDEDIQFR[166.11].L "sp|P40939|ECHA_HUMAN,tr|H0YFD6|H0YFD6_HUMAN,tr|A0A2R8Y4F5|A0A2R8Y4F5_HUMAN" 3 1420.6346 0.41 47795 13722 2 1420.63205 711.3246 "Trifunctional enzyme subunit alpha, mitochondrial OS=Homo sapiens OX=9606 GN=HADHA PE=1 SV=2" 3.92 2581.7 - 710901 - - - -1.776 - 2.768 0.636 - 583 1 2 0 -0.0025 12 0 0 0 4.33E+06 1.05E+07 - - - 6.4166 1 221125_WJC_METTL3_EV_vs_WT_F04.13723.13723.2 1.74E-07 15/24 K.VVSKEESIVSSLR.L "sp|Q9NP61|ARFG3_HUMAN,tr|H0Y6A0|H0Y6A0_HUMAN" 2 1431.7933 1.18 47796 13723 2 1431.79544 716.9039 ADP-ribosylation factor GTPase-activating protein 3 OS=Homo sapiens OX=9606 GN=ARFGAP3 PE=1 SV=1 6.11 2581.8 - 626512 - - - 1.4883 - 2.94 0.587 - 840.2 1 2 1 0.0021 13 0 0 0 1.26E+07 1.07E+07 - - - 6.1437 0.9997 221125_WJC_METTL3_EV_vs_WT_F04.13725.13725.2 0.00353 18-Nov K.EAQLPVIENK.V sp|P00747|PLMN_HUMAN 1 1139.6186 37.98 47798 13725 2 1139.618039 570.8166 Plasminogen OS=Homo sapiens OX=9606 GN=PLG PE=1 SV=2 4.53 2582.1 - 526788 - - - -0.5265 - 1.844 0.393 - 386.6 1 2 0 -0.0006 10 0 0 0 4.99E+07 1.31E+06 - - - 3.6516 0.9821 221125_WJC_METTL3_EV_vs_WT_F04.13728.13728.2 0.000529 18-Sep R.SGFSSISVSR.S "sp|P48668|K2C6C_HUMAN,sp|P04259|K2C6B_HUMAN" 2 1025.5142 1.39 47801 13728 2 1025.517916 513.7644 "Keratin, type II cytoskeletal 6C OS=Homo sapiens OX=9606 GN=KRT6C PE=1 SV=3" 9.47 2582.5 - 261453 - - - 3.6489 - 1.493 0.199 - 162.2 1 2 0 0.0037 10 0 0 0 2.64E+06 1.90E+06 - - - 1.6284 0.9995 221125_WJC_METTL3_EV_vs_WT_F04.13729.13729.2 3.33E-05 20-Nov R.YFDEISQDTGK[136.11].Y "sp|P62495|ERF1_HUMAN,tr|B7Z7P8|B7Z7P8_HUMAN" 2 1309.5918 0.12 47802 13729 2 1309.587728 655.8032 Eukaryotic peptide chain release factor subunit 1 OS=Homo sapiens OX=9606 GN=ETF1 PE=1 SV=3 4.03 2582.6 - 369129 - - - -3.0803 - 2.138 0.53 - 287.9 1 2 0 -0.004 11 0 0 0 2.68E+05 2.20E+06 - - - 5.0099 0.9998 221125_WJC_METTL3_EV_vs_WT_F04.13731.13731.2 1.50E-05 22-Oct R.FLEQQNQVLQTK.W "sp|Q7Z794|K2C1B_HUMAN,sp|P04264|K2C1_HUMAN,sp|P35908|K22E_HUMAN" 3 1474.778 999 47803 13731 2 1474.77656 738.3963 "Keratin, type II cytoskeletal 1b OS=Homo sapiens OX=9606 GN=KRT77 PE=1 SV=3" 6 2582.8 - 2.00E+06 - - - -0.9717 - 1.956 0.498 - 295.7 1 2 0 -0.0014 12 0 0 0 1.16E+08 0.00E+00 - - - 4.484 1 221125_WJC_METTL3_EV_vs_WT_F04.13733.13733.3 0.000176 15/40 R.AGVLAHLEEER[166.11].D "sp|P35580|MYH10_HUMAN,sp|P35579|MYH9_HUMAN" 2 1232.6389 0.95 47804 13733 3 1232.638293 411.8869 Myosin-10 OS=Homo sapiens OX=9606 GN=MYH10 PE=1 SV=3 4.75 2583 - 5.10E+06 - - - -0.4681 - 2.702 0.458 - 599.3 1 2 0 -0.0006 11 0 0 0 5.46E+07 5.77E+07 - - - 6.4698 0.998 221125_WJC_METTL3_EV_vs_WT_F04.13734.13734.2 3.75E-05 24-Dec R.SGSTAVGVMISPK.H "sp|O75688|PPM1B_HUMAN,tr|B8ZZF0|B8ZZF0_HUMAN,tr|A0A3B3IS24|A0A3B3IS24_HUMAN,tr|C9JIR6|C9JIR6_HUMAN" 4 1232.6435 3.14 47805 13734 2 1232.6409 617.329 Protein phosphatase 1B OS=Homo sapiens OX=9606 GN=PPM1B PE=1 SV=1 8.47 2583.1 - 3.71E+06 - - - -2.0874 - 2.478 0.172 - 547 2 2 0 -0.0026 13 0 0 0 5.74E+08 1.83E+08 - - - 2.5051 0.9677 221125_WJC_METTL3_EV_vs_WT_F04.13735.13735.3 0.205 Oct-48 R.ISDAHLADTMIGK.A sp|Q9Y657|SPIN1_HUMAN 1 1370.6864 2.49 47806 13735 3 1370.684661 457.9027 Spindlin-1 OS=Homo sapiens OX=9606 GN=SPIN1 PE=1 SV=3 5.21 2583.1 - 2.05E+06 - - - -1.2694 - 1.374 0.16 - 91.2 1 2 0 -0.0017 13 0 0 0 9.74E+07 3.91E+07 - - - 1.1848 1 221125_WJC_METTL3_EV_vs_WT_F04.13736.13736.3 4.53E-07 Dec-44 K.FIC[160.03]EQDHQNFLR[166.11].L "sp|Q92598|HS105_HUMAN,tr|A0A0A0MSM0|A0A0A0MSM0_HUMAN" 2 1615.7441 0.14 47807 13736 3 1615.743242 539.5886 Heat shock protein 105 kDa OS=Homo sapiens OX=9606 GN=HSPH1 PE=1 SV=1 5.32 2583.2 - 1.54E+06 - - - -0.5193 - 2.593 0.537 - 108.6 1 2 0 -0.0008 12 0 0 0 2.03E+07 1.41E+08 - - - 7.1678 0.9998 221125_WJC_METTL3_EV_vs_WT_F04.13738.13738.2 0.00871 20-Nov R.KLPVSSLTISR.L "sp|Q92552|RT27_HUMAN,tr|G5EA06|G5EA06_HUMAN,tr|D6RH20|D6RH20_HUMAN,tr|E5RJ73|E5RJ73_HUMAN,tr|D6RJC7|D6RJC7_HUMAN" 5 1199.7238 1.03 47809 13738 2 1199.722415 600.8692 "28S ribosomal protein S27, mitochondrial OS=Homo sapiens OX=9606 GN=MRPS27 PE=1 SV=3" 11 2583.5 - 898892 - - - -1.1311 - 2.264 0.406 - 390.4 1 2 0 -0.0014 11 0 0 0 1.58E+07 1.53E+07 - - - 4.2498 0.9992 221125_WJC_METTL3_EV_vs_WT_F04.13739.13739.2 0.00327 22-Sep K.YLIPNATQPESK[136.11].V sp|P31946|1433B_HUMAN 1 1367.7176 0.68 47810 13739 2 1367.718304 684.8661 14-3-3 protein beta\alpha OS=Homo sapiens OX=9606 GN=YWHAB PE=1 SV=3 6 2583.6 - 869647 - - - 0.4921 - 1.745 0.29 - 223.6 1 2 0 0.0007 12 0 0 0 1.99E+07 2.93E+07 - - - 2.6476 1 221125_WJC_METTL3_EV_vs_WT_F04.13740.13740.3 1.60E-06 14/48 K.SALVKPVTINVGR.A sp|Q9UJV9|DDX41_HUMAN 1 1352.814 0.85 47811 13740 3 1352.812727 451.9453 Probable ATP-dependent RNA helicase DDX41 OS=Homo sapiens OX=9606 GN=DDX41 PE=1 SV=2 11 2583.7 - 865753 - - - -0.9292 - 2.958 0.477 - 279.8 1 2 0 -0.0013 13 0 0 0 5.33E+07 6.25E+07 - - - 6.7982 1 221125_WJC_METTL3_EV_vs_WT_F04.13741.13741.2 1.14E-11 17/36 R.GLGAGAGAGEESPATSLPR.M sp|O15173|PGRC2_HUMAN 1 1696.838 1.58 47812 13741 2 1696.835537 849.4263 Membrane-associated progesterone receptor component 2 OS=Homo sapiens OX=9606 GN=PGRMC2 PE=1 SV=1 4.53 2583.8 - 856048 - - - -1.4674 - 3.37 0.688 - 671.7 1 2 0 -0.0025 19 0 0 0 1.65E+07 1.05E+07 - - - 7.1087 0.9999 221125_WJC_METTL3_EV_vs_WT_F04.13743.13743.3 0.000144 17/56 R.LLELGPKPEVAQQTR.K "sp|P53621|COPA_HUMAN,tr|A0A3B3ISC6|A0A3B3ISC6_HUMAN,tr|A0A3B3IS84|A0A3B3IS84_HUMAN,tr|A0A3B3ITI7|A0A3B3ITI7_HUMAN,tr|A0A3B3IT15|A0A3B3IT15_HUMAN" 5 1677.9414 0.08 47814 13743 3 1677.941282 560.3211 Coatomer subunit alpha OS=Homo sapiens OX=9606 GN=COPA PE=1 SV=2 6.14 2584.1 - 805927 - - - -0.0524 - 2.402 0.397 - 302.2 1 2 0 -0.0001 15 0 0 0 3.89E+06 5.01E+07 - - - 5.2527 1 221125_WJC_METTL3_EV_vs_WT_F04.13744.13744.2 1.14E-08 13/28 K.ELTVSNNDINEAGVR.V "sp|P13489|RINI_HUMAN,tr|E9PLZ3|E9PLZ3_HUMAN,tr|E9PMJ3|E9PMJ3_HUMAN,tr|E9PIM9|E9PIM9_HUMAN" 4 1629.7958 2.85 47815 13744 2 1629.796357 815.9052 Ribonuclease inhibitor OS=Homo sapiens OX=9606 GN=RNH1 PE=1 SV=2 4.14 2584.2 - 668448 - - - 0.3246 - 2.615 0.596 - 432 1 2 0 0.0005 15 0 0 0 5.82E+06 2.04E+06 - - - 5.8062 0.9995 221125_WJC_METTL3_EV_vs_WT_F04.13745.13745.2 3.75E-08 24-Dec K.TDPTTLTDEEINR.F "sp|P11586|C1TC_HUMAN,tr|F5H2F4|F5H2F4_HUMAN,tr|V9GZ78|V9GZ78_HUMAN,tr|V9GYY3|V9GYY3_HUMAN,tr|A0A494C1T2|A0A494C1T2_HUMAN" 5 1503.7053 2.02 47816 13745 2 1503.710258 752.8599 "C-1-tetrahydrofolate synthase, cytoplasmic OS=Homo sapiens OX=9606 GN=MTHFD1 PE=1 SV=4" 3.92 2584.4 - 493397 - - - 3.3092 - 2.386 0.582 - 521.7 1 2 0 0.005 13 0 0 0 3.83E+07 1.89E+07 - - - 5.57 0.9999 221125_WJC_METTL3_EV_vs_WT_F04.13746.13746.2 4.36E-05 28-Oct R.YLTESYGTGQDIDDR[166.11].L "sp|Q9UM54|MYO6_HUMAN,tr|A0A590UK86|A0A590UK86_HUMAN,tr|A0A590UK71|A0A590UK71_HUMAN,tr|A0A0D9SGC1|A0A0D9SGC1_HUMAN,tr|A0A0A0MRM8|A0A0A0MRM8_HUMAN,tr|A0A5F9ZI03|A0A5F9ZI03_HUMAN,tr|A0A590UK22|A0A590UK22_HUMAN,tr|A0A590UJY4|A0A590UJY4_HUMAN,tr|A0A590UJ40|A0A590UJ40_HUMAN,tr|A0A590UJ75|A0A590UJ75_HUMAN,tr|E7EW20|E7EW20_HUMAN,tr|A0A590UKB0|A0A590UKB0_HUMAN,tr|A0A1Y0BRN3|A0A1Y0BRN3_HUMAN" 13 1741.767 0.6 47817 13746 2 1741.766028 871.8908 Unconventional myosin-VI OS=Homo sapiens OX=9606 GN=MYO6 PE=1 SV=4 3.84 2584.5 - 407656 - - - -0.5833 - 2.254 0.581 - 163.5 1 2 0 -0.001 15 0 0 0 2.08E+06 3.44E+06 - - - 5.33 0.9997 221125_WJC_METTL3_EV_vs_WT_F04.13747.13747.2 0.000674 20-Oct K.SSTINTIMGNK[136.11].K "sp|Q9H089|LSG1_HUMAN,tr|H7C2X7|H7C2X7_HUMAN" 2 1172.5951 0.48 47818 13747 2 1172.594712 587.3048 Large subunit GTPase 1 homolog OS=Homo sapiens OX=9606 GN=LSG1 PE=1 SV=2 8.47 2584.6 - 404376 - - - -0.3079 - 1.746 0.394 - 242.9 1 2 0 -0.0004 11 0 0 0 2.73E+06 5.67E+06 - - - 3.4587 1 221125_WJC_METTL3_EV_vs_WT_F04.13749.13749.2 1.28E-05 14/28 R.YLTESYGTGQDIDDR.L "sp|Q9UM54|MYO6_HUMAN,tr|A0A590UK86|A0A590UK86_HUMAN,tr|A0A590UK71|A0A590UK71_HUMAN,tr|A0A0D9SGC1|A0A0D9SGC1_HUMAN,tr|A0A0A0MRM8|A0A0A0MRM8_HUMAN,tr|A0A5F9ZI03|A0A5F9ZI03_HUMAN,tr|A0A590UK22|A0A590UK22_HUMAN,tr|A0A590UJY4|A0A590UJY4_HUMAN,tr|A0A590UJ40|A0A590UJ40_HUMAN,tr|A0A590UJ75|A0A590UJ75_HUMAN,tr|E7EW20|E7EW20_HUMAN,tr|A0A590UKB0|A0A590UKB0_HUMAN,tr|A0A1Y0BRN3|A0A1Y0BRN3_HUMAN" 13 1731.7588 0.6 47820 13749 2 1731.760742 866.8867 Unconventional myosin-VI OS=Homo sapiens OX=9606 GN=MYO6 PE=1 SV=4 3.84 2584.9 - 229154 - - - 1.1364 - 3.1 0.663 - 780 1 2 0 0.002 15 0 0 0 2.08E+06 3.44E+06 - - - 6.7189 0.9864 221125_WJC_METTL3_EV_vs_WT_F04.13751.13751.3 0.134 Oct-36 K.NTWELKPEYR.H sp|P13984|T2FB_HUMAN 1 1334.6619 2.15 47821 13751 3 1334.661569 445.8946 General transcription factor IIF subunit 2 OS=Homo sapiens OX=9606 GN=GTF2F2 PE=1 SV=2 6.14 2585.1 - 541875 - - - -0.248 - 1.428 0.183 - 108.4 1 2 0 -0.0003 10 0 0 0 3.68E+06 1.71E+06 - - - 1.6207 1 221125_WJC_METTL3_EV_vs_WT_F04.13753.13753.3 3.07E-05 15/40 R.AGVLAHLEEER.D "sp|P35580|MYH10_HUMAN,sp|P35579|MYH9_HUMAN" 2 1222.6306 0.96 47822 13753 3 1222.628561 408.5508 Myosin-10 OS=Homo sapiens OX=9606 GN=MYH10 PE=1 SV=3 4.75 2585.4 - 6.44E+06 - - - -1.6677 - 2.805 0.438 - 462.4 1 2 0 -0.002 11 0 0 0 5.43E+07 5.65E+07 - - - 6.3527 0.9998 221125_WJC_METTL3_EV_vs_WT_F04.13754.13754.2 0.000343 20-Sep R.ISISTSGGSFR.N "sp|P13647|K2C5_HUMAN,tr|F8VV57|F8VV57_HUMAN" 2 1110.5669 1283.51 47823 13754 2 1110.566964 556.2907 "Keratin, type II cytoskeletal 5 OS=Homo sapiens OX=9606 GN=KRT5 PE=1 SV=3" 9.75 2585.4 - 5.56E+06 - - - 0.0243 - 1.959 0.454 - 192.4 1 2 0 0 11 0 0 0 6.54E+08 5.10E+05 - - - 4.2133 0.8022 221125_WJC_METTL3_EV_vs_WT_F04.13755.13755.2 0.356 12-Aug R.KIELFGR[166.11].P sp|Q86U44|MTA70_HUMAN 1 871.5155 - 47824 13755 2 871.515518 436.765 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 8.75 2585.5 - 2.70E+06 - - - 0.0115 - 1.567 0.106 - 306.2 1 1 0 0 7 0 0 0 - - - - - 1.2471 1 221125_WJC_METTL3_EV_vs_WT_F04.13759.13759.2 0.000263 17/22 R.TGYTLDVTTGQR[166.11].K "sp|O60506|HNRPQ_HUMAN,sp|O43390|HNRPR_HUMAN,tr|A0A7I2YQN2|A0A7I2YQN2_HUMAN,tr|A0A7I2V5Q6|A0A7I2V5Q6_HUMAN,tr|A0A7I2V4Z0|A0A7I2V4Z0_HUMAN,tr|A0A6Q8PHG0|A0A6Q8PHG0_HUMAN,tr|B7Z645|B7Z645_HUMAN,tr|A0A7I2V2F0|A0A7I2V2F0_HUMAN,tr|A0A6Q8PEX7|A0A6Q8PEX7_HUMAN,tr|A0A7I2V2F2|A0A7I2V2F2_HUMAN,tr|A0A7I2V4J0|A0A7I2V4J0_HUMAN,tr|F6UXX1|F6UXX1_HUMAN,tr|A0A7I2V309|A0A7I2V309_HUMAN" 13 1320.6549 1.3 47828 13759 2 1320.661188 661.3347 Heterogeneous nuclear ribonucleoprotein Q OS=Homo sapiens OX=9606 GN=SYNCRIP PE=1 SV=2 5.5 2585.8 - 1.12E+06 - - - 4.7507 - 2.827 0.536 - 871.1 1 2 0 0.0063 12 0 0 0 2.50E+08 1.92E+08 - - - 5.7323 0.9505 221125_WJC_METTL3_EV_vs_WT_F04.13761.13761.3 0.156 Aug-44 R.AQPSVSLGAPYR[166.11].G sp|Q96PK6|RBM14_HUMAN 1 1254.6596 0.61 47830 13761 3 1254.656587 419.2271 RNA-binding protein 14 OS=Homo sapiens OX=9606 GN=RBM14 PE=1 SV=2 8.79 2586.1 - 562119 - - - -2.4062 - 1.757 0.142 - 68.3 5 2 0 -0.003 12 0 0 0 1.47E+07 2.42E+07 - - - 1.3611 1 221125_WJC_METTL3_EV_vs_WT_F04.13762.13762.2 1.07E-08 17/26 K.GPSGC[160.03]VESLEVTC[160.03]R.R "sp|P47897|SYQ_HUMAN,tr|B4DDN1|B4DDN1_HUMAN,tr|H7C0R3|H7C0R3_HUMAN,tr|A0A0U1RQX5|A0A0U1RQX5_HUMAN,tr|A0A1B0GVU9|A0A1B0GVU9_HUMAN,tr|A0A0U1RQX9|A0A0U1RQX9_HUMAN" 6 1549.6865 1.53 47831 13762 2 1549.686244 775.8505 Glutamine--tRNA ligase OS=Homo sapiens OX=9606 GN=QARS1 PE=1 SV=1 4.53 2586.2 - 243753 - - - -0.151 - 3.371 0.697 - 1294.4 1 2 0 -0.0002 14 0 0 0 3.46E+06 2.26E+06 - - - 7.2385 0.9999 221125_WJC_METTL3_EV_vs_WT_F04.13764.13764.2 3.58E-05 20-Oct K.TLSDDLDEAAK[136.11].E "sp|Q9H0A0|NAT10_HUMAN,tr|A0A087WV29|A0A087WV29_HUMAN" 2 1184.5652 1.01 47833 13764 2 1184.565372 593.2899 RNA cytidine acetyltransferase OS=Homo sapiens OX=9606 GN=NAT10 PE=1 SV=2 3.84 2586.5 - 213535 - - - 0.1342 - 1.786 0.555 - 187 1 2 0 0.0002 11 0 0 0 8.35E+06 8.28E+06 - - - 4.7092 1 221125_WJC_METTL3_EV_vs_WT_F04.13767.13767.2 2.10E-05 14/22 R.TGYTLDVTTGQR.K "sp|O60506|HNRPQ_HUMAN,sp|O43390|HNRPR_HUMAN,tr|A0A7I2YQN2|A0A7I2YQN2_HUMAN,tr|A0A7I2V5Q6|A0A7I2V5Q6_HUMAN,tr|A0A7I2V4Z0|A0A7I2V4Z0_HUMAN,tr|A0A6Q8PHG0|A0A6Q8PHG0_HUMAN,tr|B7Z645|B7Z645_HUMAN,tr|A0A7I2V2F0|A0A7I2V2F0_HUMAN,tr|A0A6Q8PEX7|A0A6Q8PEX7_HUMAN,tr|A0A7I2V2F2|A0A7I2V2F2_HUMAN,tr|A0A7I2V4J0|A0A7I2V4J0_HUMAN,tr|F6UXX1|F6UXX1_HUMAN,tr|A0A7I2V309|A0A7I2V309_HUMAN" 13 1310.6466 1.27 47834 13767 2 1310.646063 656.3306 Heterogeneous nuclear ribonucleoprotein Q OS=Homo sapiens OX=9606 GN=SYNCRIP PE=1 SV=2 5.5 2586.9 - 3.73E+06 - - - -0.4433 - 2.666 0.607 - 602.8 1 2 0 -0.0006 12 0 0 0 2.42E+08 1.90E+08 - - - 6.1042 0.9995 221125_WJC_METTL3_EV_vs_WT_F04.13768.13768.2 0.00339 14-Aug R.NYYEQWGK.L "sp|P22626|ROA2_HUMAN,tr|A0A7I2YQN4|A0A7I2YQN4_HUMAN,tr|A0A7I2V4N0|A0A7I2V4N0_HUMAN,tr|A0A7I2V4N1|A0A7I2V4N1_HUMAN,tr|A0A7I2V4I6|A0A7I2V4I6_HUMAN,tr|A0A087WUI2|A0A087WUI2_HUMAN,tr|A0A7I2V4S4|A0A7I2V4S4_HUMAN,tr|A0A7I2V323|A0A7I2V323_HUMAN,tr|A0A7I2V3P1|A0A7I2V3P1_HUMAN,tr|A0A7I2V3P7|A0A7I2V3P7_HUMAN" 10 1086.4771 0.36 47835 13768 2 1086.477284 544.2458 Heterogeneous nuclear ribonucleoproteins A2\B1 OS=Homo sapiens OX=9606 GN=HNRNPA2B1 PE=1 SV=2 6 2587 - 1.46E+06 - - - 0.2062 - 1.274 0.447 - 233.8 1 2 0 0.0002 8 0 0 0 2.73E+07 7.56E+07 - - - 3.0728 0.9989 221125_WJC_METTL3_EV_vs_WT_F04.13769.13769.2 0.00623 22-Jun K.YLIPNATQPESK.V sp|P31946|1433B_HUMAN 1 1359.7034 0.68 47836 13769 2 1359.703458 680.859 14-3-3 protein beta\alpha OS=Homo sapiens OX=9606 GN=YWHAB PE=1 SV=3 6 2587.1 - 1.89E+06 - - - 0.0199 - 1.17 0.379 - 85.9 1 2 0 0 12 0 0 0 2.06E+07 3.04E+07 - - - 2.2534 0.9927 221125_WJC_METTL3_EV_vs_WT_F04.13770.13770.2 0.00807 18-Oct K.STVVPVPYEK[136.11].M "sp|P78347|GTF2I_HUMAN,tr|A0A494C1K3|A0A494C1K3_HUMAN" 2 1125.6161 1.63 47837 13770 2 1125.61764 563.8153 General transcription factor II-I OS=Homo sapiens OX=9606 GN=GTF2I PE=1 SV=2 5.72 2587.2 - 1.68E+06 - - - 1.345 - 1.7 0.086 - 362.1 1 2 0 0.0015 10 0 0 0 3.09E+07 1.90E+07 - - - 1.1569 0.9997 221125_WJC_METTL3_EV_vs_WT_F04.13771.13771.2 0.00112 18-Oct K.QSLPPGLAVK[136.11].E sp|P63173|RL38_HUMAN 1 1016.611 1.17 47838 13771 2 1016.609753 509.3128 60S ribosomal protein L38 OS=Homo sapiens OX=9606 GN=RPL38 PE=1 SV=2 8.75 2587.3 - 1.67E+06 - - - -1.2079 - 1.627 0.452 - 313.8 1 2 0 -0.0012 10 0 0 0 3.63E+07 3.11E+07 - - - 3.7377 1 221125_WJC_METTL3_EV_vs_WT_F04.13772.13772.3 9.12E-08 15/44 K.FIC[160.03]EQDHQNFLR.L "sp|Q92598|HS105_HUMAN,tr|A0A0A0MSM0|A0A0A0MSM0_HUMAN" 2 1605.7358 0.14 47839 13772 3 1605.734778 536.2525 Heat shock protein 105 kDa OS=Homo sapiens OX=9606 GN=HSPH1 PE=1 SV=1 5.32 2587.4 - 1.30E+06 - - - -0.6433 - 2.72 0.581 - 276.5 1 2 0 -0.001 12 0 0 0 2.03E+07 1.41E+08 - - - 7.7909 0.9998 221125_WJC_METTL3_EV_vs_WT_F04.13773.13773.3 0.000119 Nov-44 R.AQPSVSLGAPYR.G sp|Q96PK6|RBM14_HUMAN 1 1244.6513 0.64 47840 13773 3 1244.650901 415.8911 RNA-binding protein 14 OS=Homo sapiens OX=9606 GN=RBM14 PE=1 SV=2 8.79 2587.5 - 835509 - - - -0.3495 - 2.205 0.334 - 194.9 1 2 0 -0.0004 12 0 0 0 1.67E+07 2.62E+07 - - - 4.4554 1 221125_WJC_METTL3_EV_vs_WT_F04.13775.13775.2 1.61E-05 16/26 K.NVTELNEPLSNEER[166.11].N sp|P61981|1433G_HUMAN 1 1652.7881 1.39 47842 13775 2 1652.783191 827.4013 14-3-3 protein gamma OS=Homo sapiens OX=9606 GN=YWHAG PE=1 SV=2 4.09 2587.7 - 382847 - - - -2.978 - 3.241 0.606 - 808.5 1 2 0 -0.0049 14 0 0 0 6.02E+06 4.34E+06 - - - 6.4662 0.9934 221125_WJC_METTL3_EV_vs_WT_F04.13777.13777.2 0.0222 24-Jul K.SALVKPVTINVGR.A sp|Q9UJV9|DDX41_HUMAN 1 1352.814 0.86 47844 13777 2 1352.816496 677.4143 Probable ATP-dependent RNA helicase DDX41 OS=Homo sapiens OX=9606 GN=DDX41 PE=1 SV=2 11 2588 - 262410 - - - 1.8569 - 1.591 0.164 - 102.4 1 2 0 0.0025 13 0 0 0 3.26E+06 3.78E+06 - - - 1.4433 0.8981 221125_WJC_METTL3_EV_vs_WT_F04.13780.13780.3 0.279 Sep-40 R.EIAQEFKTDLR.F "sp|Q5TEC6|H3PS2_HUMAN,tr|A0A590UJL8|A0A590UJL8_HUMAN" 2 1348.6987 1.06 47845 13780 3 1348.69665 450.5735 Histone HIST2H3PS2 OS=Homo sapiens OX=9606 GN=H3-2 PE=1 SV=1 4.68 2588.4 - 8.00E+06 - - - -1.5052 - 1.417 0.171 - 94.9 1 2 1 -0.002 11 0 0 0 1.65E+08 1.56E+08 - - - 1.4361 0.9999 221125_WJC_METTL3_EV_vs_WT_F04.13782.13782.3 3.32E-05 Nov-44 K.ITVTSEVPFSK[136.11]R[166.11].Y "sp|P35268|RL22_HUMAN,tr|K7EKS7|K7EKS7_HUMAN,tr|K7ERI7|K7ERI7_HUMAN,tr|K7EMH1|K7EMH1_HUMAN,tr|K7ELC4|K7ELC4_HUMAN,tr|K7EP65|K7EP65_HUMAN" 6 1380.7732 0.64 47847 13782 3 1380.770973 461.265 60S ribosomal protein L22 OS=Homo sapiens OX=9606 GN=RPL22 PE=1 SV=2 8.75 2588.5 - 3.44E+06 - - - -1.6027 - 2.355 0.418 - 167.1 1 2 0 -0.0022 12 0 0 0 4.99E+07 7.76E+07 - - - 5.5739 0.9993 221125_WJC_METTL3_EV_vs_WT_F04.13783.13783.2 9.44E-05 18-Oct K.STVVPVPYEK.M "sp|P78347|GTF2I_HUMAN,tr|A0A494C1K3|A0A494C1K3_HUMAN" 2 1117.6019 1.63 47848 13783 2 1117.601635 559.8082 General transcription factor II-I OS=Homo sapiens OX=9606 GN=GTF2I PE=1 SV=2 5.72 2588.6 - 2.27E+06 - - - -0.2604 - 1.707 0.297 - 360.7 1 2 0 -0.0003 10 0 0 0 3.09E+07 1.90E+07 - - - 2.7272 0.9911 221125_WJC_METTL3_EV_vs_WT_F04.13784.13784.2 1.64 14-Jul K.IEISELNR.V "sp|P04264|K2C1_HUMAN,sp|P35908|K22E_HUMAN" 2 972.524 339.93 47849 13784 2 972.523155 487.2693 "Keratin, type II cytoskeletal 1 OS=Homo sapiens OX=9606 GN=KRT1 PE=1 SV=6" 4.53 2588.6 - 1.65E+06 - - - -0.8792 - 1.492 0.073 - 155.8 1 2 0 -0.0009 8 0 0 0 1.81E+08 5.33E+05 - - - 0.7866 0.9995 221125_WJC_METTL3_EV_vs_WT_F04.13785.13785.2 0.00156 14-Sep R.NYYEQWGK[136.11].L "sp|P22626|ROA2_HUMAN,tr|A0A7I2YQN4|A0A7I2YQN4_HUMAN,tr|A0A7I2V4N0|A0A7I2V4N0_HUMAN,tr|A0A7I2V4N1|A0A7I2V4N1_HUMAN,tr|A0A7I2V4I6|A0A7I2V4I6_HUMAN,tr|A0A087WUI2|A0A087WUI2_HUMAN,tr|A0A7I2V4S4|A0A7I2V4S4_HUMAN,tr|A0A7I2V323|A0A7I2V323_HUMAN,tr|A0A7I2V3P1|A0A7I2V3P1_HUMAN,tr|A0A7I2V3P7|A0A7I2V3P7_HUMAN" 10 1094.4913 1.29 47850 13785 2 1094.490317 548.2529 Heterogeneous nuclear ribonucleoproteins A2\B1 OS=Homo sapiens OX=9606 GN=HNRNPA2B1 PE=1 SV=2 6 2588.8 - 1.22E+06 - - - -0.8616 - 1.434 0.424 - 305.2 1 2 0 -0.0009 8 0 0 0 1.46E+07 1.13E+07 - - - 3.2595 0.9988 221125_WJC_METTL3_EV_vs_WT_F04.13787.13787.3 0.029 15/48 R.LC[160.03]SGVLGTVVHGK[136.11].V "sp|Q9Y6C9|MTCH2_HUMAN,tr|E9PIE4|E9PIE4_HUMAN" 2 1333.7268 0.79 47852 13787 3 1333.725281 445.5829 Mitochondrial carrier homolog 2 OS=Homo sapiens OX=9606 GN=MTCH2 PE=1 SV=1 8.23 2589 - 809038 - - - -1.1059 - 2.019 0.247 - 218.5 1 2 0 -0.0015 13 0 0 0 9.18E+06 1.17E+07 - - - 3.1984 0.9999 221125_WJC_METTL3_EV_vs_WT_F04.13788.13788.3 0.000462 Dec-36 K.DLAEDAPWK[136.11]K[136.11].L "sp|O75369|FLNB_HUMAN,sp|Q14315|FLNC_HUMAN,sp|P21333|FLNA_HUMAN,tr|A0A7P0NMY4|A0A7P0NMY4_HUMAN,tr|Q60FE5|Q60FE5_HUMAN,tr|A0A7I2V3E6|A0A7I2V3E6_HUMAN,tr|A0A804HK76|A0A804HK76_HUMAN,tr|A0A804HJC2|A0A804HJC2_HUMAN,tr|A0A087WWY3|A0A087WWY3_HUMAN,tr|A0A804HL72|A0A804HL72_HUMAN,tr|F8WE98|F8WE98_HUMAN" 11 1187.6157 0.31 47853 13788 3 1187.614997 396.8792 Filamin-B OS=Homo sapiens OX=9606 GN=FLNB PE=1 SV=2 4.56 2589.2 - 772122 - - - -0.6248 - 2.056 0.393 - 175.9 1 2 0 -0.0007 10 0 0 0 7.08E+06 2.29E+07 - - - 5.0263 1 221125_WJC_METTL3_EV_vs_WT_F04.13789.13789.2 9.71E-08 14/24 K.TDPTTLTDEEINR[166.11].F "sp|P11586|C1TC_HUMAN,tr|F5H2F4|F5H2F4_HUMAN,tr|V9GZ78|V9GZ78_HUMAN,tr|V9GYY3|V9GYY3_HUMAN,tr|A0A494C1T2|A0A494C1T2_HUMAN" 5 1513.7136 2.02 47854 13789 2 1513.712119 757.8641 "C-1-tetrahydrofolate synthase, cytoplasmic OS=Homo sapiens OX=9606 GN=MTHFD1 PE=1 SV=4" 3.92 2589.3 - 726873 - - - -0.9467 - 2.6 0.583 - 466.2 1 2 0 -0.0014 13 0 0 0 3.83E+07 1.89E+07 - - - 5.7989 0.9999 221125_WJC_METTL3_EV_vs_WT_F04.13790.13790.2 6.19E-06 16/26 K.LSGLEQPQGALQTR[166.11].R "sp|Q6RFH5|WDR74_HUMAN,tr|E9PS41|E9PS41_HUMAN,tr|H0YFP2|H0YFP2_HUMAN" 3 1506.803 1.16 47855 13790 2 1506.801858 754.4088 WD repeat-containing protein 74 OS=Homo sapiens OX=9606 GN=WDR74 PE=1 SV=1 6 2589.4 - 615306 - - - -0.742 - 3.021 0.418 - 631.3 1 2 0 -0.0011 14 0 0 0 8.99E+06 7.78E+06 - - - 4.9024 0.9995 221125_WJC_METTL3_EV_vs_WT_F04.13791.13791.2 0.00232 20-Nov K.TLSDDLDEAAK.E "sp|Q9H0A0|NAT10_HUMAN,tr|A0A087WV29|A0A087WV29_HUMAN" 2 1176.551 0.98 47856 13791 2 1176.548495 589.2828 RNA cytidine acetyltransferase OS=Homo sapiens OX=9606 GN=NAT10 PE=1 SV=2 3.84 2589.5 - 579449 - - - -2.1402 - 1.795 0.468 - 250.2 1 2 0 -0.0025 11 0 0 0 8.35E+06 8.55E+06 - - - 4.0794 0.9997 221125_WJC_METTL3_EV_vs_WT_F04.13792.13792.3 1.90E-05 14/36 K.DLAEDAPWKK.L "sp|O75369|FLNB_HUMAN,sp|Q14315|FLNC_HUMAN,sp|P21333|FLNA_HUMAN,tr|A0A7P0NMY4|A0A7P0NMY4_HUMAN,tr|Q60FE5|Q60FE5_HUMAN,tr|A0A7I2V3E6|A0A7I2V3E6_HUMAN,tr|A0A804HK76|A0A804HK76_HUMAN,tr|A0A804HJC2|A0A804HJC2_HUMAN,tr|A0A087WWY3|A0A087WWY3_HUMAN,tr|A0A804HL72|A0A804HL72_HUMAN,tr|F8WE98|F8WE98_HUMAN" 11 1171.5873 0.3 47857 13792 3 1171.582865 391.5364 Filamin-B OS=Homo sapiens OX=9606 GN=FLNB PE=1 SV=2 4.56 2589.6 - 563576 - - - -3.8188 - 2.454 0.454 - 184.5 1 2 0 -0.0045 10 0 0 0 7.18E+06 2.37E+07 - - - 6.2221 0.9972 221125_WJC_METTL3_EV_vs_WT_F04.13793.13793.3 0.142 Oct-36 R.FILPVNEGKK.L "sp|Q9Y3A5|SBDS_HUMAN,tr|A0A087X020|A0A087X020_HUMAN" 2 1143.6652 1.73 47858 13793 3 1143.663271 382.229 Ribosome maturation protein SBDS OS=Homo sapiens OX=9606 GN=SBDS PE=1 SV=4 8.59 2589.8 - 564141 - - - -1.6823 - 1.483 0.285 - 115.2 1 2 0 -0.0019 10 0 0 0 7.76E+06 4.48E+06 - - - 2.8678 0.9074 221125_WJC_METTL3_EV_vs_WT_F04.13798.13798.2 0.0993 20-Aug R.EIAQEFKTDLR.F "sp|Q5TEC6|H3PS2_HUMAN,tr|A0A590UJL8|A0A590UJL8_HUMAN" 2 1348.6987 0.71 47861 13798 2 1348.69865 675.3566 Histone HIST2H3PS2 OS=Homo sapiens OX=9606 GN=H3-2 PE=1 SV=1 4.68 2590.4 - 1.38E+06 - - - -0.0222 - 1.418 0.095 - 137.9 1 2 1 0 11 0 0 0 2.21E+07 3.12E+07 - - - 0.6875 0.9972 221125_WJC_METTL3_EV_vs_WT_F04.13800.13800.2 0.0676 18-Aug K.QSLPPGLAVK.E sp|P63173|RL38_HUMAN 1 1008.5968 1.16 47863 13800 2 1008.595996 505.3057 60S ribosomal protein L38 OS=Homo sapiens OX=9606 GN=RPL38 PE=1 SV=2 8.75 2590.5 - 1.45E+06 - - - -0.7783 - 1.47 0.202 - 179.8 1 2 0 -0.0008 10 0 0 0 3.84E+07 3.32E+07 - - - 1.6081 0.9989 221125_WJC_METTL3_EV_vs_WT_F04.13801.13801.3 0.0228 Dec-44 K.VFDGIPPPYDK[136.11]K[136.11].K "sp|P40429|RL13A_HUMAN,sp|Q6NVV1|R13P3_HUMAN,tr|M0QYS1|M0QYS1_HUMAN,tr|Q8J015|Q8J015_HUMAN,tr|A0A7I2V2L9|A0A7I2V2L9_HUMAN,tr|A0A7I2V5L3|A0A7I2V5L3_HUMAN" 6 1390.7468 0.84 47864 13801 3 1390.743508 464.5895 60S ribosomal protein L13a OS=Homo sapiens OX=9606 GN=RPL13A PE=1 SV=2 5.93 2590.6 - 1.04E+06 - - - -2.3333 - 2.013 0.3 - 160.2 1 2 0 -0.0032 12 0 0 0 1.57E+07 1.86E+07 - - - 3.8231 1 221125_WJC_METTL3_EV_vs_WT_F04.13802.13802.2 1.01E-06 17/26 K.LSGLEQPQGALQTR.R "sp|Q6RFH5|WDR74_HUMAN,tr|E9PS41|E9PS41_HUMAN,tr|H0YFP2|H0YFP2_HUMAN" 3 1496.7947 1.16 47865 13802 2 1496.793238 749.4046 WD repeat-containing protein 74 OS=Homo sapiens OX=9606 GN=WDR74 PE=1 SV=1 6 2590.7 - 886362 - - - -0.9808 - 3.162 0.57 - 625.7 1 2 0 -0.0015 14 0 0 0 8.99E+06 7.78E+06 - - - 6.1394 0.9998 221125_WJC_METTL3_EV_vs_WT_F04.13803.13803.2 5.49E-06 20-Dec K.LANTC[160.03]FNEIEK.Q "sp|Q9NP61|ARFG3_HUMAN,tr|H0Y6A0|H0Y6A0_HUMAN" 2 1337.6286 0.91 47866 13803 2 1337.629256 669.8216 ADP-ribosylation factor GTPase-activating protein 3 OS=Homo sapiens OX=9606 GN=ARFGAP3 PE=1 SV=1 4.53 2590.9 - 816332 - - - 0.5263 - 2.574 0.376 - 596.6 1 2 0 0.0007 11 0 0 0 9.27E+06 1.01E+07 - - - 4.3756 1 221125_WJC_METTL3_EV_vs_WT_F04.13805.13805.2 9.36E-08 14/26 K.NVTELNEPLSNEER.N sp|P61981|1433G_HUMAN 1 1642.7798 1.39 47868 13805 2 1642.777938 822.3972 14-3-3 protein gamma OS=Homo sapiens OX=9606 GN=YWHAG PE=1 SV=2 4.09 2591.1 - 456394 - - - -1.1596 - 2.845 0.63 - 571.6 1 2 0 -0.0019 14 0 0 0 6.02E+06 4.34E+06 - - - 6.3174 0.9991 221125_WJC_METTL3_EV_vs_WT_F04.13806.13806.2 0.0277 22-Aug K.AFSGYLGTDQSK.W "sp|P10768|ESTD_HUMAN,tr|H7BZT7|H7BZT7_HUMAN,tr|U3KQT1|U3KQT1_HUMAN,tr|X6RA14|X6RA14_HUMAN" 4 1272.5986 0.99 47869 13806 2 1272.599111 637.3066 S-formylglutathione hydrolase OS=Homo sapiens OX=9606 GN=ESD PE=1 SV=2 5.88 2591.3 - 397985 - - - 0.3764 - 1.481 0.334 - 161.1 1 2 0 0.0005 12 0 0 0 6.00E+06 6.04E+06 - - - 2.5411 0.9432 221125_WJC_METTL3_EV_vs_WT_F04.13810.13810.2 0.518 20-Jul R.EIAQEFK[136.11]TDLR[166.11].F "sp|Q5TEC6|H3PS2_HUMAN,tr|A0A590UJL8|A0A590UJL8_HUMAN" 2 1366.7212 0.71 47871 13810 2 1366.720067 684.3679 Histone HIST2H3PS2 OS=Homo sapiens OX=9606 GN=H3-2 PE=1 SV=1 4.68 2591.8 - 1.97E+06 - - - -0.7924 - 1.409 0.157 - 119.3 1 2 1 -0.0011 11 0 0 0 2.21E+07 3.12E+07 - - - 1.1278 0.9931 221125_WJC_METTL3_EV_vs_WT_F04.13812.13812.2 2.64E-07 24-Dec R.R[166.11]AEQDSTTVAAFA.S "sp|Q86U44|MTA70_HUMAN,tr|F5H6D8|F5H6D8_HUMAN,tr|H0YFV6|H0YFV6_HUMAN,tr|B4DTN4|B4DTN4_HUMAN" 4 1375.6607 0.1 47873 13812 2 1375.660275 688.8376 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 4.37 2592 - 3.18E+06 - - - -0.3293 - 1.742 0.605 - 246.2 1 1 0 -0.0005 13 0 0 0 1.29E+07 1.24E+08 - - - 4.9339 0.9974 221125_WJC_METTL3_EV_vs_WT_F04.13815.13815.3 0.00412 Sep-36 K.K[136.11]VVEDIEYLK[136.11].F "sp|O95299|NDUAA_HUMAN,tr|A0A7I2V4N8|A0A7I2V4N8_HUMAN,tr|A0A7I2V2N6|A0A7I2V2N6_HUMAN,tr|H7C1Y7|H7C1Y7_HUMAN,tr|A0A7I2V5B2|A0A7I2V5B2_HUMAN,tr|A0A7I2V419|A0A7I2V419_HUMAN,tr|A0A7I2V2W9|A0A7I2V2W9_HUMAN,tr|A0A7I2V2X3|A0A7I2V2X3_HUMAN,tr|H7C2W5|H7C2W5_HUMAN,tr|A0A7I2YQU0|A0A7I2YQU0_HUMAN,tr|H7C2X4|H7C2X4_HUMAN,tr|A0A7I2V438|A0A7I2V438_HUMAN,tr|E7ESZ7|E7ESZ7_HUMAN,tr|A0A7I2V5L0|A0A7I2V5L0_HUMAN,tr|A0A087WXC5|A0A087WXC5_HUMAN,tr|A0A7I2V458|A0A7I2V458_HUMAN,tr|A0A7I2V594|A0A7I2V594_HUMAN,tr|A0A7I2V327|A0A7I2V327_HUMAN,tr|A0A7I2V5U7|A0A7I2V5U7_HUMAN" 19 1250.7093 0.79 47876 13815 3 1250.707934 417.9104 "NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 10, mitochondrial OS=Homo sapiens OX=9606 GN=NDUFA10 PE=1 SV=1" 4.68 2592.3 - 701752 - - - -1.0962 - 2.122 0.175 - 205.3 1 2 0 -0.0014 10 0 0 0 8.35E+06 1.05E+07 - - - 2.6879 1 221125_WJC_METTL3_EV_vs_WT_F04.13823.13823.3 0.000577 14/52 R.IFHTVTTTDDPVIR[166.11].K "sp|O15371|EIF3D_HUMAN,tr|B0QYA5|B0QYA5_HUMAN,tr|B0QYA4|B0QYA4_HUMAN" 3 1623.8496 1.03 47882 13823 3 1623.850245 542.2905 Eukaryotic translation initiation factor 3 subunit D OS=Homo sapiens OX=9606 GN=EIF3D PE=1 SV=1 5.21 2593.2 - 1.48E+06 - - - 0.4021 - 2.9 0.447 - 242.3 1 2 0 0.0007 14 0 0 0 5.23E+07 5.06E+07 - - - 6.3529 0.9993 221125_WJC_METTL3_EV_vs_WT_F04.13825.13825.3 0.00159 14/44 K.LKEYEAAVEQLK.S "sp|Q5T9A4|ATD3B_HUMAN,tr|H0Y2W2|H0Y2W2_HUMAN" 2 1419.7609 2.04 47884 13825 3 1419.760919 474.2609 ATPase family AAA domain-containing protein 3B OS=Homo sapiens OX=9606 GN=ATAD3B PE=1 SV=1 4.79 2593.5 - 1.09E+06 - - - -0.019 - 2.114 0.373 - 219.7 1 2 1 0 12 0 0 0 3.02E+07 1.48E+07 - - - 4.7735 0.9999 221125_WJC_METTL3_EV_vs_WT_F04.13826.13826.3 0.000379 14/48 K.EIVVIHQDPEALK[136.11].D "sp|P41252|SYIC_HUMAN,tr|A0A804HL54|A0A804HL54_HUMAN,tr|A0A804HIV9|A0A804HIV9_HUMAN,tr|A0A804HJN6|A0A804HJN6_HUMAN,tr|A0A804HHW9|A0A804HHW9_HUMAN,tr|A0A0A0MSX9|A0A0A0MSX9_HUMAN,tr|J3KR24|J3KR24_HUMAN,tr|A0A804HJ36|A0A804HJ36_HUMAN" 8 1497.8282 1.07 47885 13826 3 1497.829228 500.2834 "Isoleucine--tRNA ligase, cytoplasmic OS=Homo sapiens OX=9606 GN=IARS1 PE=1 SV=2" 4.65 2593.6 - 968504 - - - 0.657 - 2.499 0.399 - 321 1 2 0 0.001 13 0 0 0 1.24E+07 1.16E+07 - - - 5.4714 1 221125_WJC_METTL3_EV_vs_WT_F04.13827.13827.3 3.20E-07 13/40 K.NFEDVAFDEKK.N "sp|P07237|PDIA1_HUMAN,tr|A0A7P0TA97|A0A7P0TA97_HUMAN,tr|A0A7P0T8C0|A0A7P0T8C0_HUMAN,tr|H7BZ94|H7BZ94_HUMAN,tr|B3KTQ9|B3KTQ9_HUMAN,tr|A0A7P0TA71|A0A7P0TA71_HUMAN,tr|I3L4M2|I3L4M2_HUMAN,tr|A0A7P0T9D6|A0A7P0T9D6_HUMAN,tr|A0A7P0T9K9|A0A7P0T9K9_HUMAN,tr|H0Y3Z3|H0Y3Z3_HUMAN,tr|A0A7P0TA35|A0A7P0TA35_HUMAN,tr|A0A7P0TB26|A0A7P0TB26_HUMAN,tr|A0A7P0T9U6|A0A7P0T9U6_HUMAN,tr|I3L0S0|I3L0S0_HUMAN,tr|I3L3P5|I3L3P5_HUMAN,tr|A0A7P0T8J3|A0A7P0T8J3_HUMAN,tr|A0A7P0T8X1|A0A7P0T8X1_HUMAN" 17 1340.6248 1.71 47886 13827 3 1340.625682 447.8822 Protein disulfide-isomerase OS=Homo sapiens OX=9606 GN=P4HB PE=1 SV=3 4.32 2593.7 - 934745 - - - 0.6236 - 2.469 0.57 - 222.8 1 2 0 0.0008 11 0 0 0 1.30E+07 7.60E+06 - - - 7.4623 0.9998 221125_WJC_METTL3_EV_vs_WT_F04.13828.13828.3 4.49E-05 17/48 R.AVIGIGIEEEDRK.H sp|O94906|PRP6_HUMAN 1 1427.762 3.55 47887 13828 3 1427.763151 476.9279 Pre-mRNA-processing factor 6 OS=Homo sapiens OX=9606 GN=PRPF6 PE=1 SV=1 4.41 2593.8 - 909412 - - - 0.7999 - 2.037 0.357 - 304.8 1 2 0 0.0011 13 0 0 0 1.81E+07 5.09E+06 - - - 4.4489 0.9998 221125_WJC_METTL3_EV_vs_WT_F04.13829.13829.3 0.000446 Oct-40 K.HPTLLQDPDLR.Q "sp|O60749|SNX2_HUMAN,tr|D6RC15|D6RC15_HUMAN" 2 1303.6885 1.87 47888 13829 3 1303.687626 435.5701 Sorting nexin-2 OS=Homo sapiens OX=9606 GN=SNX2 PE=1 SV=2 5.21 2593.9 - 810477 - - - -0.6321 - 2.01 0.363 - 199.5 1 2 0 -0.0008 11 0 0 0 1.40E+07 7.47E+06 - - - 4.5701 0.999 221125_WJC_METTL3_EV_vs_WT_F04.13830.13830.3 0.00484 Sep-40 R.LTPYEVDELR[166.11]R[166.11].K "sp|Q92841|DDX17_HUMAN,tr|A0A5H1ZRQ2|A0A5H1ZRQ2_HUMAN,tr|A0A1X7SBZ2|A0A1X7SBZ2_HUMAN" 3 1409.7418 1.7 47889 13830 3 1409.741299 470.9212 Probable ATP-dependent RNA helicase DDX17 OS=Homo sapiens OX=9606 GN=DDX17 PE=1 SV=2 4.68 2594 - 573084 - - - -0.3334 - 1.967 0.256 - 160.1 1 2 0 -0.0005 11 0 0 0 1.22E+07 7.19E+06 - - - 3.3159 0.9994 221125_WJC_METTL3_EV_vs_WT_F04.13832.13832.2 0.000558 16/32 R.AIGGGLSSVGGGSSTIK.Y "sp|P48668|K2C6C_HUMAN,sp|P02538|K2C6A_HUMAN" 2 1446.7678 999 47891 13832 2 1446.771877 724.3912 "Keratin, type II cytoskeletal 6C OS=Homo sapiens OX=9606 GN=KRT6C PE=1 SV=3" 8.8 2594.3 - 447065 - - - 2.8028 - 2.485 0.426 - 596.7 1 2 0 0.0041 17 0 0 0 1.48E+07 0.00E+00 - - - 4.4241 0.9999 221125_WJC_METTL3_EV_vs_WT_F04.13834.13834.2 2.14E-07 24-Dec R.ILDETQEAVEYQR[166.11].Q "sp|Q96FZ7|CHMP6_HUMAN,tr|I3L4A1|I3L4A1_HUMAN,tr|I3L3E4|I3L3E4_HUMAN,tr|I3L4G8|I3L4G8_HUMAN" 4 1602.7765 1.32 47893 13834 2 1602.775983 802.3955 Charged multivesicular body protein 6 OS=Homo sapiens OX=9606 GN=CHMP6 PE=1 SV=3 4 2594.5 - 350722 - - - -0.3138 - 2.723 0.555 - 506.5 1 2 0 -0.0005 13 0 0 0 6.13E+06 4.64E+06 - - - 5.7111 1 221125_WJC_METTL3_EV_vs_WT_F04.13838.13838.2 2.83E-06 24-Dec R.ELAEDGYSGVEVR[166.11].V "sp|P23396|RS3_HUMAN,tr|H0YEU2|H0YEU2_HUMAN,tr|E9PL09|E9PL09_HUMAN,tr|E9PK82|E9PK82_HUMAN,tr|F2Z2S8|F2Z2S8_HUMAN,tr|H0YCJ7|H0YCJ7_HUMAN,tr|E9PQ96|E9PQ96_HUMAN,tr|E9PJH4|E9PJH4_HUMAN,tr|E9PPU1|E9PPU1_HUMAN,tr|H0YF32|H0YF32_HUMAN" 10 1432.671 0.75 47896 13838 2 1432.669765 717.3428 40S ribosomal protein S3 OS=Homo sapiens OX=9606 GN=RPS3 PE=1 SV=2 4 2595 - 2.80E+06 - - - -0.8327 - 2.61 0.599 - 502.6 1 2 0 -0.0012 13 0 0 0 2.02E+07 2.68E+07 - - - 5.927 0.998 221125_WJC_METTL3_EV_vs_WT_F04.13839.13839.3 0.651 Oct-48 R.YLGDLSGGQVLK[136.11]K[136.11].L "sp|P09601|HMOX1_HUMAN,tr|B1AHA8|B1AHA8_HUMAN,tr|A0A7I2V3I1|A0A7I2V3I1_HUMAN" 3 1392.7948 5.06 47897 13839 3 1392.795956 465.2722 Heme oxygenase 1 OS=Homo sapiens OX=9606 GN=HMOX1 PE=1 SV=1 8.5 2595.1 - 1.12E+06 - - - 0.8544 - 2.037 0.214 - 75.8 1 2 0 0.0012 13 0 0 0 5.06E+07 1.00E+07 - - - 2.8546 1 221125_WJC_METTL3_EV_vs_WT_F04.13840.13840.3 6.27E-07 14/44 R.R[166.11]IPWTAASSQLK[136.11].E "sp|Q9GZT3|SLIRP_HUMAN,tr|H0YJW7|H0YJW7_HUMAN,tr|A0A087WUN7|A0A087WUN7_HUMAN,tr|G3V2S9|G3V2S9_HUMAN,tr|H0YJU7|H0YJU7_HUMAN,tr|H0YJ07|H0YJ07_HUMAN,tr|H0YJ40|H0YJ40_HUMAN,tr|G3V4X6|G3V4X6_HUMAN" 8 1374.7739 1.17 47898 13840 3 1374.772722 459.2652 "SRA stem-loop-interacting RNA-binding protein, mitochondrial OS=Homo sapiens OX=9606 GN=SLIRP PE=1 SV=1" 11 2595.1 - 7.59E+06 - - - -0.8234 - 2.799 0.54 - 280.4 1 2 0 -0.0011 12 0 0 0 1.83E+08 1.57E+08 - - - 7.4131 1 221125_WJC_METTL3_EV_vs_WT_F04.13841.13841.3 7.60E-09 15/52 R.IFHTVTTTDDPVIR.K "sp|O15371|EIF3D_HUMAN,tr|B0QYA5|B0QYA5_HUMAN,tr|B0QYA4|B0QYA4_HUMAN" 3 1613.8413 1.03 47899 13841 3 1613.842351 538.9544 Eukaryotic translation initiation factor 3 subunit D OS=Homo sapiens OX=9606 GN=EIF3D PE=1 SV=1 5.21 2595.1 - 4.17E+06 - - - 0.6376 - 2.729 0.58 - 287.5 1 2 0 0.001 14 0 0 0 5.18E+07 5.02E+07 - - - 7.6741 0.9994 221125_WJC_METTL3_EV_vs_WT_F04.13842.13842.3 0.0172 Nov-44 R.K[136.11]LYGDADYLEER[166.11].H "sp|P17812|PYRG1_HUMAN,tr|B4E1E0|B4E1E0_HUMAN,tr|A0A3B3IRI2|A0A3B3IRI2_HUMAN" 3 1488.7215 0.88 47900 13842 3 1488.72024 497.2478 CTP synthase 1 OS=Homo sapiens OX=9606 GN=CTPS1 PE=1 SV=2 4.32 2595.2 - 1.24E+06 - - - -0.8759 - 2.002 0.294 - 161.8 1 2 0 -0.0013 12 0 0 0 9.56E+06 1.09E+07 - - - 3.7415 0.9834 221125_WJC_METTL3_EV_vs_WT_F04.13844.13844.3 0.0646 Nov-36 K.LAIK[136.11]PFYQNK[136.11].D "sp|Q99590|SCAFB_HUMAN,tr|F8VXG7|F8VXG7_HUMAN,tr|A0A087WTB7|A0A087WTB7_HUMAN" 3 1236.7201 1.33 47902 13844 3 1236.724351 413.2473 Protein SCAF11 OS=Homo sapiens OX=9606 GN=SCAF11 PE=1 SV=2 9.7 2595.4 - 1.19E+06 - - - 3.4017 - 1.771 0.206 - 101.5 1 2 0 0.0042 10 0 0 0 1.22E+07 9.15E+06 - - - 2.5047 1 221125_WJC_METTL3_EV_vs_WT_F04.13845.13845.2 6.38E-06 15/24 R.ILDETQEAVEYQR.Q "sp|Q96FZ7|CHMP6_HUMAN,tr|I3L4A1|I3L4A1_HUMAN,tr|I3L3E4|I3L3E4_HUMAN,tr|I3L4G8|I3L4G8_HUMAN" 4 1592.7682 1.31 47903 13845 2 1592.765438 797.3914 Charged multivesicular body protein 6 OS=Homo sapiens OX=9606 GN=CHMP6 PE=1 SV=3 4 2595.6 - 830332 - - - -1.7441 - 2.925 0.606 - 861.1 1 2 0 -0.0028 13 0 0 0 6.23E+06 4.75E+06 - - - 6.2707 1 221125_WJC_METTL3_EV_vs_WT_F04.13846.13846.2 4.29E-08 16/28 R.GGAATGWYGANPDPR.Y sp|Q9H2Z4|NKX24_HUMAN 1 1488.6746 0.57 47904 13846 2 1488.670124 745.3446 Homeobox protein Nkx-2.4 OS=Homo sapiens OX=9606 GN=NKX2-4 PE=1 SV=3 5.84 2595.7 - 625296 - - - -3 - 3.007 0.567 - 468.7 1 2 0 -0.0045 15 0 0 0 7.86E+06 1.39E+07 - - - 5.9342 0.9998 221125_WJC_METTL3_EV_vs_WT_F04.13847.13847.2 0.00115 20-Oct K.IDLQVPSSESK.A sp|Q92541|RTF1_HUMAN 1 1201.619 0.99 47905 13847 2 1201.618814 601.8168 RNA polymerase-associated protein RTF1 homolog OS=Homo sapiens OX=9606 GN=RTF1 PE=1 SV=4 4.37 2595.8 - 452584 - - - -0.1823 - 2.255 0.377 - 274.8 1 2 0 -0.0002 11 0 0 0 3.67E+06 3.71E+06 - - - 4.0252 0.9998 221125_WJC_METTL3_EV_vs_WT_F04.13849.13849.2 6.38E-06 28-Sep R.LVDSPDIQPVGTC[160.03]EK.E sp|Q9UQR0|SCML2_HUMAN 1 1656.8029 0.71 47907 13849 2 1656.803781 829.4087 Sex comb on midleg-like protein 2 OS=Homo sapiens OX=9606 GN=SCML2 PE=1 SV=1 4.03 2596.1 - 220556 - - - 0.5396 - 1.824 0.549 - 144.3 1 2 0 0.0009 15 0 0 0 3.41E+06 4.82E+06 - - - 4.5733 0.9993 221125_WJC_METTL3_EV_vs_WT_F04.13853.13853.2 2.81E-05 22-Nov K.ESGPSGIETELR[166.11].S "sp|Q8NI36|WDR36_HUMAN,tr|A0A0A0MTB8|A0A0A0MTB8_HUMAN" 2 1283.6233 1.88 47909 13853 2 1283.619379 642.8189 WD repeat-containing protein 36 OS=Homo sapiens OX=9606 GN=WDR36 PE=1 SV=1 4.25 2596.6 - 679008 - - - -3.0391 - 2.255 0.461 - 483.6 1 2 0 -0.0039 12 0 0 0 1.42E+07 7.57E+06 - - - 4.5843 0.7867 221125_WJC_METTL3_EV_vs_WT_F04.13858.13858.3 2.02 Jul-36 K.DLQHPNEFIR[166.11].G "sp|P53618|COPB_HUMAN,tr|E9PP73|E9PP73_HUMAN,tr|E9PP63|E9PP63_HUMAN,tr|E9PKQ1|E9PKQ1_HUMAN" 4 1277.6392 0.59 47914 13858 3 1277.639012 426.887 Coatomer subunit beta OS=Homo sapiens OX=9606 GN=COPB1 PE=1 SV=3 5.32 2597.2 - 532407 - - - -0.1511 - 1.492 0.043 - 70.3 3 2 0 -0.0002 10 0 0 0 5.70E+06 9.59E+06 - - - -0.0329 0.9994 221125_WJC_METTL3_EV_vs_WT_F04.13860.13860.2 4.84E-07 13/26 K.LPGELEPVQATQNK[136.11].T "sp|O75821|EIF3G_HUMAN,tr|K7ER90|K7ER90_HUMAN,tr|K7EL20|K7EL20_HUMAN,tr|K7EP16|K7EP16_HUMAN" 4 1530.8133 1.54 47916 13860 2 1530.818703 766.4139 Eukaryotic translation initiation factor 3 subunit G OS=Homo sapiens OX=9606 GN=EIF3G PE=1 SV=2 4.53 2597.5 - 513302 - - - 3.5151 - 2.769 0.532 - 490.5 1 2 0 0.0054 14 0 0 0 4.57E+07 2.96E+07 - - - 5.5245 0.953 221125_WJC_METTL3_EV_vs_WT_F04.13863.13863.2 3.20E-06 15/26 K.LPGELEPVQATQNK.T "sp|O75821|EIF3G_HUMAN,tr|K7ER90|K7ER90_HUMAN,tr|K7EL20|K7EL20_HUMAN,tr|K7EP16|K7EP16_HUMAN" 4 1522.7991 1.57 47919 13863 2 1523.796725 762.4068 Eukaryotic translation initiation factor 3 subunit G OS=Homo sapiens OX=9606 GN=EIF3G PE=1 SV=2 4.53 2597.9 - 485364 - - - 655.1114 - 2.424 0.478 - 631.3 1 2 0 0.9976 14 0 0 0 4.71E+07 2.99E+07 - - - 4.4802 0.9842 221125_WJC_METTL3_EV_vs_WT_F04.13864.13864.2 2.44E-05 18-Oct K.DTSIQEVVSR.P "sp|Q8IWC1|MA7D3_HUMAN,tr|A0A0A0MRP0|A0A0A0MRP0_HUMAN" 2 1132.5724 2.22 47920 13864 2 1132.571096 567.2935 MAP7 domain-containing protein 3 OS=Homo sapiens OX=9606 GN=MAP7D3 PE=1 SV=2 4.37 2598 - 466054 - - - -1.1664 - 1.88 0.438 - 345.5 1 1 0 -0.0013 10 0 0 0 6.80E+06 3.06E+06 - - - 4.0377 0.9987 221125_WJC_METTL3_EV_vs_WT_F04.13867.13867.2 0.000846 26-Sep R.IFHTVTTTDDPVIR[166.11].K "sp|O15371|EIF3D_HUMAN,tr|B0QYA5|B0QYA5_HUMAN,tr|B0QYA4|B0QYA4_HUMAN" 3 1623.8496 0.98 47923 13867 2 1623.843699 812.9321 Eukaryotic translation initiation factor 3 subunit D OS=Homo sapiens OX=9606 GN=EIF3D PE=1 SV=1 5.21 2598.4 - 256966 - - - -3.629 - 1.902 0.478 - 140.1 1 2 0 -0.0059 14 0 0 0 1.77E+06 1.81E+06 - - - 4.183 0.9531 221125_WJC_METTL3_EV_vs_WT_F04.13871.13871.2 0.0734 14-Aug K.IELFGR[166.11]PH.N sp|Q86U44|MTA70_HUMAN 1 977.5322 0.01 47925 13871 2 977.531607 489.7734 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 6.75 2598.8 - 3.81E+06 - - - -0.6271 - 1.66 0.275 - 215.4 1 1 0 -0.0006 8 0 0 0 2.69E+05 2.04E+07 - - - 2.6005 0.9999 221125_WJC_METTL3_EV_vs_WT_F04.13875.13875.3 0.00022 Oct-32 R.K[136.11]MVDQLFC[160.03]K[136.11].K "sp|P78347|GTF2I_HUMAN,tr|A0A494C0Q7|A0A494C0Q7_HUMAN,tr|A0A494C1K3|A0A494C1K3_HUMAN" 3 1183.6064 1.27 47929 13875 3 1183.606253 395.5428 General transcription factor II-I OS=Homo sapiens OX=9606 GN=GTF2I PE=1 SV=2 8.2 2599.2 - 818739 - - - -0.1546 - 1.722 0.43 - 185.6 1 2 0 -0.0002 9 0 0 0 4.44E+07 3.51E+07 - - - 4.972 0.9623 221125_WJC_METTL3_EV_vs_WT_F04.13876.13876.3 0.427 Sep-44 K.VMITHC[160.03]NLNEFK.E "sp|Q86SF2|GALT7_HUMAN,tr|H0YAK0|H0YAK0_HUMAN,tr|H0YAH3|H0YAH3_HUMAN" 3 1504.7167 2.01 47930 13876 3 1504.712944 502.5795 N-acetylgalactosaminyltransferase 7 OS=Homo sapiens OX=9606 GN=GALNT7 PE=1 SV=1 6.71 2599.3 - 808966 - - - -2.4662 - 1.482 0.185 - 69.1 2 2 0 -0.0037 12 0 0 0 4.60E+06 2.29E+06 - - - 1.5526 0.9997 221125_WJC_METTL3_EV_vs_WT_F04.13877.13877.3 0.00803 Nov-44 K.FTATASLGVIHK.G "sp|Q99460|PSMD1_HUMAN,tr|A0A7I2V4X0|A0A7I2V4X0_HUMAN,tr|A0A7I2V2K8|A0A7I2V2K8_HUMAN,tr|A0A7I2YQY1|A0A7I2YQY1_HUMAN,tr|A0A7I2V523|A0A7I2V523_HUMAN,tr|A0A7I2V641|A0A7I2V641_HUMAN,tr|A0A7I2V491|A0A7I2V491_HUMAN,tr|A0A7I2YQI9|A0A7I2YQI9_HUMAN,tr|A0A7I2V262|A0A7I2V262_HUMAN,tr|A0A087WW66|A0A087WW66_HUMAN,tr|A0A7P0MW50|A0A7P0MW50_HUMAN,tr|A0A7I2V5C8|A0A7I2V5C8_HUMAN,tr|A0A7I2V479|A0A7I2V479_HUMAN" 13 1243.6925 0.39 47931 13877 3 1243.689819 415.5714 26S proteasome non-ATPase regulatory subunit 1 OS=Homo sapiens OX=9606 GN=PSMD1 PE=1 SV=2 8.76 2599.4 - 582141 - - - -2.1332 - 2.073 0.39 - 97.7 1 2 0 -0.0027 12 0 0 0 3.76E+06 9.56E+06 - - - 4.908 1 221125_WJC_METTL3_EV_vs_WT_F04.13882.13882.2 1.97E-07 24-Dec K.GQLC[160.03]ELSC[160.03]STDYR[166.11].M "sp|Q99873|ANM1_HUMAN,tr|E9PKG1|E9PKG1_HUMAN" 2 1597.674 2.36 47936 13882 2 1597.678517 799.8443 Protein arginine N-methyltransferase 1 OS=Homo sapiens OX=9606 GN=PRMT1 PE=1 SV=3 4.37 2600.1 - 304442 - - - 2.8197 - 2.659 0.645 - 588.2 1 2 0 0.0045 13 0 0 0 3.04E+07 1.29E+07 - - - 6.3135 0.9997 221125_WJC_METTL3_EV_vs_WT_F04.13885.13885.2 0.00168 20-Nov K.QQQLLNEENLR[166.11].K "sp|Q5T9A4|ATD3B_HUMAN,sp|Q9NVI7|ATD3A_HUMAN,tr|H0Y2W2|H0Y2W2_HUMAN" 3 1393.7189 1.19 47938 13885 2 1393.7186 697.8667 ATPase family AAA domain-containing protein 3B OS=Homo sapiens OX=9606 GN=ATAD3B PE=1 SV=1 4.53 2600.4 - 309674 - - - -0.2239 - 2.085 0.344 - 320.3 1 2 0 -0.0003 11 0 0 0 3.63E+07 3.06E+07 - - - 3.5694 0.9998 221125_WJC_METTL3_EV_vs_WT_F04.13886.13886.2 0.00136 22-Dec R.GEPPLPEEDLSK.L "sp|O15372|EIF3H_HUMAN,tr|B3KS98|B3KS98_HUMAN,tr|A0A087WZK9|A0A087WZK9_HUMAN" 3 1309.6402 2.18 47939 13886 2 1309.640412 655.8274 Eukaryotic translation initiation factor 3 subunit H OS=Homo sapiens OX=9606 GN=EIF3H PE=1 SV=1 4 2600.5 - 5.62E+06 - - - 0.1909 - 2.245 0.402 - 336.6 1 2 0 0.0003 12 0 0 0 3.01E+08 1.38E+08 - - - 4.1379 0.9997 221125_WJC_METTL3_EV_vs_WT_F04.13887.13887.2 0.0395 16-Oct K.QQQVDIPLR.L sp|Q9NZI8|IF2B1_HUMAN 1 1095.6037 1.63 47940 13887 2 1095.604569 548.8091 Insulin-like growth factor 2 mRNA-binding protein 1 OS=Homo sapiens OX=9606 GN=IGF2BP1 PE=1 SV=2 5.84 2600.5 - 4.27E+06 - - - 0.8324 - 2.082 0.386 - 609 1 2 0 0.0009 9 0 0 0 6.42E+08 3.95E+08 - - - 4.0133 0.9996 221125_WJC_METTL3_EV_vs_WT_F04.13888.13888.2 0.00174 16-Aug K.QQQVDIPLR[166.11].L sp|Q9NZI8|IF2B1_HUMAN 1 1105.6119 1.62 47941 13888 2 1105.610367 553.8132 Insulin-like growth factor 2 mRNA-binding protein 1 OS=Homo sapiens OX=9606 GN=IGF2BP1 PE=1 SV=2 5.84 2600.6 - 3.47E+06 - - - -1.411 - 1.769 0.39 - 382 1 2 0 -0.0016 9 0 0 0 6.41E+08 3.95E+08 - - - 3.5713 0.9993 221125_WJC_METTL3_EV_vs_WT_F04.13890.13890.3 2.66E-05 Dec-36 R.YTK[136.11]EELLDIK[136.11].E "sp|Q9NRA8|4ET_HUMAN,tr|B1AKL6|B1AKL6_HUMAN,tr|B1AKL5|B1AKL5_HUMAN,tr|B1AKL4|B1AKL4_HUMAN" 4 1266.7042 1.2 47943 13890 3 1266.703812 423.242 Eukaryotic translation initiation factor 4E transporter OS=Homo sapiens OX=9606 GN=EIF4ENIF1 PE=1 SV=2 4.68 2600.7 - 2.16E+06 - - - -0.3213 - 2.322 0.342 - 161.7 1 2 1 -0.0004 10 0 0 0 9.21E+07 7.68E+07 - - - 4.8131 0.9989 221125_WJC_METTL3_EV_vs_WT_F04.13891.13891.2 0.131 12-Oct K.HIDFSLR.S sp|P46781|RS9_HUMAN 1 886.4661 1.01 47944 13891 2 886.465965 444.2403 40S ribosomal protein S9 OS=Homo sapiens OX=9606 GN=RPS9 PE=1 SV=3 6.74 2600.8 - 1.62E+06 - - - -0.1534 - 1.644 0.225 - 340.9 1 2 0 -0.0001 7 0 0 0 1.59E+08 1.57E+08 - - - 2.278 1 221125_WJC_METTL3_EV_vs_WT_F04.13892.13892.3 8.94E-07 17/56 K.GYAEVVVASENSVHK.L "sp|Q8N684|CPSF7_HUMAN,tr|C9J323|C9J323_HUMAN,tr|F5H047|F5H047_HUMAN,tr|F5H669|F5H669_HUMAN,tr|F5H6M0|F5H6M0_HUMAN,tr|J3QT54|J3QT54_HUMAN,tr|C9J286|C9J286_HUMAN" 7 1587.7893 1.59 47945 13892 3 1587.791655 530.2704 Cleavage and polyadenylation specificity factor subunit 7 OS=Homo sapiens OX=9606 GN=CPSF7 PE=1 SV=1 5.4 2600.9 - 1.06E+06 - - - 1.492 - 2.928 0.502 - 261.1 1 2 0 0.0024 15 0 0 0 1.94E+07 1.22E+07 - - - 6.9394 1 221125_WJC_METTL3_EV_vs_WT_F04.13894.13894.3 1.08E-07 14/56 K.GYAEVVVASENSVHK[136.11].L "sp|Q8N684|CPSF7_HUMAN,tr|C9J323|C9J323_HUMAN,tr|F5H047|F5H047_HUMAN,tr|F5H669|F5H669_HUMAN,tr|F5H6M0|F5H6M0_HUMAN,tr|J3QT54|J3QT54_HUMAN,tr|C9J286|C9J286_HUMAN" 7 1595.8035 1.57 47947 13894 3 1595.805335 532.9418 Cleavage and polyadenylation specificity factor subunit 7 OS=Homo sapiens OX=9606 GN=CPSF7 PE=1 SV=1 5.4 2601.1 - 941962 - - - 1.1587 - 2.582 0.559 - 157.9 1 2 0 0.0018 15 0 0 0 1.91E+07 1.22E+07 - - - 7.2469 1 221125_WJC_METTL3_EV_vs_WT_F04.13895.13895.2 0.00584 16/20 K.IRLENEIQTYR.S "sp|P13645|K1C10_HUMAN,tr|A0A1B0GVI3|A0A1B0GVI3_HUMAN" 2 1433.7627 2554.12 47948 13895 2 1433.762277 717.8886 "Keratin, type I cytoskeletal 10 OS=Homo sapiens OX=9606 GN=KRT10 PE=1 SV=6" 6.14 2601.2 - 919597 - - - -0.279 - 3.03 0.51 - 346.3 1 2 1 -0.0004 11 0 0 0 8.27E+08 3.24E+05 - - - 5.8067 1 221125_WJC_METTL3_EV_vs_WT_F04.13896.13896.2 2.48E-06 16-Dec R.KMVDQLFC[160.03]K.K "sp|P78347|GTF2I_HUMAN,tr|A0A494C0Q7|A0A494C0Q7_HUMAN,tr|A0A494C1K3|A0A494C1K3_HUMAN" 3 1167.578 1.46 47949 13896 2 1167.578557 584.7963 General transcription factor II-I OS=Homo sapiens OX=9606 GN=GTF2I PE=1 SV=2 8.2 2601.3 - 890843 - - - 0.4462 - 2.456 0.564 - 512 1 2 0 0.0005 9 0 0 0 3.05E+07 2.09E+07 - - - 5.806 1 221125_WJC_METTL3_EV_vs_WT_F04.13897.13897.3 5.05E-06 15/48 K.VLAMSGDPNYLHR[166.11].M "sp|P30153|2AAA_HUMAN,tr|E9PH38|E9PH38_HUMAN,tr|B3KQV6|B3KQV6_HUMAN" 3 1481.7325 0.98 47950 13897 3 1481.732505 494.9181 Serine\threonine-protein phosphatase 2A 65 kDa regulatory subunit A alpha isoform OS=Homo sapiens OX=9606 GN=PPP2R1A PE=1 SV=4 6.71 2601.4 - 793725 - - - 0.0351 - 3.008 0.473 - 386 1 2 0 0.0001 13 0 0 0 2.09E+07 2.13E+07 - - - 6.7993 0.9999 221125_WJC_METTL3_EV_vs_WT_F04.13899.13899.2 3.43E-07 24-Dec R.VNEISVEVDSDPR[166.11].A "sp|P27708|PYR1_HUMAN,tr|F8VPD4|F8VPD4_HUMAN,tr|H7C2E4|H7C2E4_HUMAN" 3 1467.7081 1.02 47952 13899 2 1467.708766 734.8613 CAD protein OS=Homo sapiens OX=9606 GN=CAD PE=1 SV=3 3.92 2601.7 - 492468 - - - 0.4728 - 2.409 0.579 - 312.3 1 2 0 0.0007 13 0 0 0 7.88E+06 7.71E+06 - - - 5.5738 0.9998 221125_WJC_METTL3_EV_vs_WT_F04.13900.13900.2 0.000658 20-Oct K.GISQEQMQEFR[166.11].A "sp|O43707|ACTN4_HUMAN,tr|F5GXS2|F5GXS2_HUMAN,tr|H7C144|H7C144_HUMAN" 3 1361.6273 0.07 47953 13900 2 1361.628911 681.8209 Alpha-actinin-4 OS=Homo sapiens OX=9606 GN=ACTN4 PE=1 SV=2 4.53 2601.8 - 492874 - - - 1.1692 - 2.025 0.494 - 408.4 1 2 0 0.0016 11 0 0 0 4.63E+06 7.03E+07 - - - 4.5979 0.9877 221125_WJC_METTL3_EV_vs_WT_F04.13901.13901.2 0.0461 18-Sep R.YTK[136.11]EELLDIK[136.11].E "sp|Q9NRA8|4ET_HUMAN,tr|B1AKL6|B1AKL6_HUMAN,tr|B1AKL5|B1AKL5_HUMAN,tr|B1AKL4|B1AKL4_HUMAN" 4 1266.7042 0.21 47954 13901 2 1266.703389 634.3594 Eukaryotic translation initiation factor 4E transporter OS=Homo sapiens OX=9606 GN=EIF4ENIF1 PE=1 SV=2 4.68 2602 - 352299 - - - -0.6552 - 1.606 0.267 - 182.1 1 2 1 -0.0008 10 0 0 0 2.27E+06 1.07E+07 - - - 2.3352 0.999 221125_WJC_METTL3_EV_vs_WT_F04.13904.13904.2 9.72E-06 22-Oct R.AQPSVSLGAPYR.G sp|Q96PK6|RBM14_HUMAN 1 1244.6513 1.88 47956 13904 2 1244.648531 623.3329 RNA-binding protein 14 OS=Homo sapiens OX=9606 GN=RBM14 PE=1 SV=2 8.79 2602.2 - 1.03E+07 - - - -2.2536 - 1.891 0.343 - 369.6 1 2 0 -0.0028 12 0 0 0 7.40E+08 3.95E+08 - - - 3.2499 0.9998 221125_WJC_METTL3_EV_vs_WT_F04.13905.13905.2 0.000846 13/22 R.R[166.11]IPWTAASSQLK[136.11].E "sp|Q9GZT3|SLIRP_HUMAN,tr|H0YJW7|H0YJW7_HUMAN,tr|A0A087WUN7|A0A087WUN7_HUMAN,tr|G3V2S9|G3V2S9_HUMAN,tr|H0YJU7|H0YJU7_HUMAN,tr|H0YJ07|H0YJ07_HUMAN,tr|H0YJ40|H0YJ40_HUMAN,tr|G3V4X6|G3V4X6_HUMAN" 8 1374.7739 1.35 47957 13905 2 1374.774308 688.3942 "SRA stem-loop-interacting RNA-binding protein, mitochondrial OS=Homo sapiens OX=9606 GN=SLIRP PE=1 SV=1" 11 2602.3 - 3.83E+06 - - - 0.3302 - 2.368 0.397 - 381.9 1 2 0 0.0005 12 0 0 0 5.91E+07 4.38E+07 - - - 4.2413 0.9999 221125_WJC_METTL3_EV_vs_WT_F04.13906.13906.3 0.000287 14/36 R.YTKEELLDIK.E "sp|Q9NRA8|4ET_HUMAN,tr|B1AKL6|B1AKL6_HUMAN,tr|B1AKL5|B1AKL5_HUMAN,tr|B1AKL4|B1AKL4_HUMAN" 4 1250.6758 1.19 47958 13906 3 1250.675095 417.8992 Eukaryotic translation initiation factor 4E transporter OS=Homo sapiens OX=9606 GN=EIF4ENIF1 PE=1 SV=2 4.68 2602.3 - 2.92E+06 - - - -0.5789 - 2.431 0.54 - 224.5 1 2 1 -0.0007 10 0 0 0 9.20E+07 7.75E+07 - - - 7.1545 0.9998 221125_WJC_METTL3_EV_vs_WT_F04.13907.13907.2 0.000193 18-Nov K.TILNLENSNK.S sp|Q8IX12|CCAR1_HUMAN 1 1144.6088 3.47 47959 13907 2 1144.609916 573.3117 Cell division cycle and apoptosis regulator protein 1 OS=Homo sapiens OX=9606 GN=CCAR1 PE=1 SV=2 5.66 2602.4 - 1.69E+06 - - - 0.9733 - 1.953 0.514 - 276 1 2 0 0.0011 10 0 0 0 5.04E+07 1.45E+07 - - - 4.7055 0.9999 221125_WJC_METTL3_EV_vs_WT_F04.13909.13909.2 0.000519 14/16 R.K[136.11]MVDQLFC[160.03]K[136.11].K "sp|P78347|GTF2I_HUMAN,tr|A0A494C0Q7|A0A494C0Q7_HUMAN,tr|A0A494C1K3|A0A494C1K3_HUMAN" 3 1183.6064 1.53 47961 13909 2 1183.607334 592.8105 General transcription factor II-I OS=Homo sapiens OX=9606 GN=GTF2I PE=1 SV=2 8.2 2602.6 - 1.18E+06 - - - 0.7587 - 2.506 0.537 - 788.9 1 2 0 0.0009 9 0 0 0 3.23E+07 2.11E+07 - - - 5.6648 0.9998 221125_WJC_METTL3_EV_vs_WT_F04.13911.13911.3 0.00367 Oct-32 K.SFYQFQHYR[166.11].A sp|P42285|MTREX_HUMAN 1 1284.5915 0.8 47963 13911 3 1284.592257 429.2045 Exosome RNA helicase MTR4 OS=Homo sapiens OX=9606 GN=MTREX PE=1 SV=3 8.33 2602.8 - 823364 - - - 0.5691 - 1.729 0.4 - 150.4 1 2 0 0.0007 9 0 0 0 1.17E+07 1.45E+07 - - - 4.6496 0.9999 221125_WJC_METTL3_EV_vs_WT_F04.13912.13912.2 0.000163 20-Nov K.GISQEQMQEFR.A "sp|O43707|ACTN4_HUMAN,tr|F5GXS2|F5GXS2_HUMAN,tr|H7C144|H7C144_HUMAN" 3 1351.619 0.46 47964 13912 2 1351.618731 676.8168 Alpha-actinin-4 OS=Homo sapiens OX=9606 GN=ACTN4 PE=1 SV=2 4.53 2602.9 - 616906 - - - -0.2353 - 1.91 0.522 - 374.6 1 2 0 -0.0003 11 0 0 0 4.46E+06 9.80E+06 - - - 4.647 0.9985 221125_WJC_METTL3_EV_vs_WT_F04.13914.13914.3 0.0399 Sep-40 R.ERPAAISIEIK.S sp|Q15208|STK38_HUMAN 1 1225.703 4.47 47966 13914 3 1225.704106 409.575 Serine\threonine-protein kinase 38 OS=Homo sapiens OX=9606 GN=STK38 PE=1 SV=1 6.24 2603.2 - 535458 - - - 0.8722 - 1.574 0.291 - 88.5 1 2 0 0.0011 11 0 0 0 8.05E+06 1.80E+06 - - - 3.0727 0.99 221125_WJC_METTL3_EV_vs_WT_F04.13917.13917.2 4.08E-05 26-Sep A.AEAVTADSEVLEER.Q "sp|Q9NPL8|TIDC1_HUMAN,tr|G3XA94|G3XA94_HUMAN,tr|F8WC42|F8WC42_HUMAN,tr|F8WAU6|F8WAU6_HUMAN,tr|C9JU35|C9JU35_HUMAN,tr|F8WB00|F8WB00_HUMAN,tr|C9JR82|C9JR82_HUMAN" 7 1517.7209 1.83 47969 13917 2 1517.721006 759.8677 "Complex I assembly factor TIMMDC1, mitochondrial OS=Homo sapiens OX=9606 GN=TIMMDC1 PE=1 SV=2" 3.91 2603.6 - 312518 - - - 0.0488 - 1.777 0.521 - 120.8 1 1 0 0.0001 14 0 0 0 6.76E+06 3.69E+06 - - - 4.3318 0.8343 221125_WJC_METTL3_EV_vs_WT_F04.13918.13918.3 1.46 Oct-40 K.EFGLLK[136.11]PTSAR[166.11].S sp|Q14966|ZN638_HUMAN 1 1235.6993 2.54 47970 13918 3 1235.698101 412.907 Zinc finger protein 638 OS=Homo sapiens OX=9606 GN=ZNF638 PE=1 SV=2 8.85 2603.7 - 309120 - - - -0.9638 - 1.564 0.029 - 96.8 1 2 0 -0.0012 11 0 0 0 8.27E+06 3.26E+06 - - - 0.1335 0.9865 221125_WJC_METTL3_EV_vs_WT_F04.13919.13919.2 0.00184 22-Oct F.QFGVSNLGQEEK[136.11].K sp|P49790|NU153_HUMAN 1 1342.6608 1.67 47971 13919 2 1342.660748 672.3377 Nuclear pore complex protein Nup153 OS=Homo sapiens OX=9606 GN=NUP153 PE=1 SV=2 4.53 2603.8 - 297922 - - - -0.0715 - 1.807 0.447 - 418.1 1 1 0 -0.0001 12 0 0 0 4.78E+06 2.86E+06 - - - 3.8993 0.9997 221125_WJC_METTL3_EV_vs_WT_F04.13921.13921.2 2.67E-06 22-Oct R.AQPSVSLGAPYR[166.11].G sp|Q96PK6|RBM14_HUMAN 1 1254.6596 1.57 47972 13921 2 1254.660092 628.3371 RNA-binding protein 14 OS=Homo sapiens OX=9606 GN=RBM14 PE=1 SV=2 8.79 2604 - 3.23E+06 - - - 0.3874 - 2.125 0.348 - 376.9 1 2 0 0.0005 12 0 0 0 7.60E+07 4.85E+07 - - - 3.5945 1 221125_WJC_METTL3_EV_vs_WT_F04.13923.13923.3 0.000261 Dec-44 R.QTGIVLNR[166.11]PVLR[166.11].G "sp|Q13435|SF3B2_HUMAN,tr|E9PPJ0|E9PPJ0_HUMAN,tr|H0YCG1|H0YCG1_HUMAN,tr|E9PJ04|E9PJ04_HUMAN,tr|E9PJT3|E9PJT3_HUMAN" 5 1384.8418 1.03 47973 13923 3 1384.841367 462.6212 Splicing factor 3B subunit 2 OS=Homo sapiens OX=9606 GN=SF3B2 PE=1 SV=2 12 2604.3 - 3.91E+06 - - - -0.2823 - 2.239 0.46 - 268.3 1 2 0 -0.0004 12 0 0 0 1.09E+08 1.06E+08 - - - 5.9026 1 221125_WJC_METTL3_EV_vs_WT_F04.13925.13925.3 1.21E-07 16/68 R.VLVASSVVAGESQKPELK.A sp|Q06787|FMR1_HUMAN 1 1840.0306 1.93 47975 13925 3 1840.030995 614.3508 Synaptic functional regulator FMR1 OS=Homo sapiens OX=9606 GN=FMR1 PE=1 SV=1 6.11 2604.4 - 3.68E+06 - - - 0.2261 - 3.16 0.599 - 222.2 1 2 0 0.0004 18 0 0 0 7.20E+07 3.74E+07 - - - 8.0832 0.9998 221125_WJC_METTL3_EV_vs_WT_F04.13926.13926.3 0.000956 Nov-44 R.QTGIVLNRPVLR.G "sp|Q13435|SF3B2_HUMAN,tr|E9PPJ0|E9PPJ0_HUMAN,tr|H0YCG1|H0YCG1_HUMAN,tr|E9PJ04|E9PJ04_HUMAN,tr|E9PJT3|E9PJT3_HUMAN" 5 1364.8252 1.03 47976 13926 3 1364.824961 455.949 Splicing factor 3B subunit 2 OS=Homo sapiens OX=9606 GN=SF3B2 PE=1 SV=2 12 2604.4 - 2.71E+06 - - - -0.1883 - 1.886 0.374 - 241.6 1 2 0 -0.0003 12 0 0 0 1.09E+08 1.06E+08 - - - 4.4683 1 221125_WJC_METTL3_EV_vs_WT_F04.13928.13928.3 0.0007 13/48 K.VLAMSGDPNYLHR.M "sp|P30153|2AAA_HUMAN,tr|E9PH38|E9PH38_HUMAN,tr|B3KQV6|B3KQV6_HUMAN" 3 1471.7242 0.86 47978 13928 3 1471.722761 491.582 Serine\threonine-protein phosphatase 2A 65 kDa regulatory subunit A alpha isoform OS=Homo sapiens OX=9606 GN=PPP2R1A PE=1 SV=4 6.71 2604.6 - 1.31E+06 - - - -0.9662 - 2.771 0.438 - 233.3 1 2 0 -0.0014 13 0 0 0 1.82E+07 2.12E+07 - - - 6.1862 0.9995 221125_WJC_METTL3_EV_vs_WT_F04.13929.13929.3 0.000889 Oct-32 K.SFYQFQHYR.A sp|P42285|MTREX_HUMAN 1 1274.5833 0.79 47979 13929 3 1274.583601 425.8684 Exosome RNA helicase MTR4 OS=Homo sapiens OX=9606 GN=MTREX PE=1 SV=3 8.33 2604.7 - 1.08E+06 - - - 0.2707 - 1.796 0.319 - 120.9 1 2 0 0.0003 9 0 0 0 1.14E+07 1.45E+07 - - - 3.8612 0.9999 221125_WJC_METTL3_EV_vs_WT_F04.13930.13930.2 0.0316 14/26 K.TAEEQGELAFQDAK.T sp|Q6KB66|K2C80_HUMAN 1 1535.7104 7.51 47980 13930 2 1535.711075 768.8625 "Keratin, type II cytoskeletal 80 OS=Homo sapiens OX=9606 GN=KRT80 PE=1 SV=2" 4 2604.8 - 795394 - - - 0.461 - 3.042 0.5 - 802.8 1 2 0 0.0007 14 0 0 0 1.92E+07 2.55E+06 - - - 5.5256 0.9998 221125_WJC_METTL3_EV_vs_WT_F04.13931.13931.2 6.66E-05 13/22 K.QSSSEISLAVER.A sp|P48634|PRC2A_HUMAN 1 1304.6572 1.06 47981 13931 2 1304.659824 653.3359 Protein PRRC2A OS=Homo sapiens OX=9606 GN=PRRC2A PE=1 SV=3 4.53 2605 - 581850 - - - 2.0044 - 2.776 0.531 - 715.9 1 2 0 0.0026 12 0 0 0 5.09E+07 4.79E+07 - - - 5.6486 0.9989 221125_WJC_METTL3_EV_vs_WT_F04.13932.13932.2 0.0148 16-Jul K.DTDSINLYK.N "sp|O14980|XPO1_HUMAN,tr|A0A7I2V488|A0A7I2V488_HUMAN,tr|A0A7I2V461|A0A7I2V461_HUMAN,tr|A0A7I2V2H0|A0A7I2V2H0_HUMAN,tr|A0A7I2V3N0|A0A7I2V3N0_HUMAN,tr|A0A7I2V4A3|A0A7I2V4A3_HUMAN,tr|A0A7I2V3W6|A0A7I2V3W6_HUMAN,tr|A0A7I2YQV4|A0A7I2YQV4_HUMAN,tr|A0A7I2YQX3|A0A7I2YQX3_HUMAN,tr|A0A7I2V2Y6|A0A7I2V2Y6_HUMAN,tr|A0A7I2V6B9|A0A7I2V6B9_HUMAN,tr|A0A7I2V3P3|A0A7I2V3P3_HUMAN,tr|A0A7I2V2S3|A0A7I2V2S3_HUMAN" 13 1067.5135 0.75 47982 13932 2 1067.511942 534.764 Exportin-1 OS=Homo sapiens OX=9606 GN=XPO1 PE=1 SV=1 4.21 2605.1 - 420309 - - - -1.4642 - 1.497 0.335 - 145.3 1 2 0 -0.0016 9 0 0 0 4.73E+06 6.33E+06 - - - 2.6821 1 221125_WJC_METTL3_EV_vs_WT_F04.13935.13935.3 8.88E-08 19/68 R.VLVASSVVAGESQK[136.11]PELK[136.11].A sp|Q06787|FMR1_HUMAN 1 1856.059 1.93 47983 13935 3 1856.059021 619.6936 Synaptic functional regulator FMR1 OS=Homo sapiens OX=9606 GN=FMR1 PE=1 SV=1 6.11 2605.5 - 3.45E+06 - - - 0.0226 - 3.692 0.6 - 391.7 1 2 0 0 18 0 0 0 7.15E+07 3.71E+07 - - - 8.4819 1 221125_WJC_METTL3_EV_vs_WT_F04.13938.13938.3 3.93E-05 15/36 R.LAQAWFNTHR.E sp|Q96A33|CCD47_HUMAN 1 1242.6258 1.01 47986 13938 3 1242.62696 415.2159 PAT complex subunit CCDC47 OS=Homo sapiens OX=9606 GN=CCDC47 PE=1 SV=1 9.76 2605.8 - 927654 - - - 0.9416 - 2.517 0.43 - 257.1 1 2 0 0.0012 10 0 0 0 1.63E+07 1.61E+07 - - - 6.0295 0.9967 221125_WJC_METTL3_EV_vs_WT_F04.13939.13939.2 0.0502 16-Jul R.LHVSNIPFR.F "sp|O43251|RFOX2_HUMAN,sp|Q9NWB1|RFOX1_HUMAN,sp|A6NFN3|RFOX3_HUMAN,tr|A0A6Q8PGE0|A0A6Q8PGE0_HUMAN,tr|A0A6Q8PH77|A0A6Q8PH77_HUMAN,tr|A0A286YEU2|A0A286YEU2_HUMAN,tr|A0A087X2B1|A0A087X2B1_HUMAN,tr|F8VR27|F8VR27_HUMAN,tr|B7Z1U7|B7Z1U7_HUMAN,tr|B0QYY6|B0QYY6_HUMAN,tr|B0QYV1|B0QYV1_HUMAN,tr|A0A6Q8PHA3|A0A6Q8PHA3_HUMAN,tr|A0A3B3ITL7|A0A3B3ITL7_HUMAN,tr|F8VZY7|F8VZY7_HUMAN,tr|B0QYY4|B0QYY4_HUMAN,tr|J3KNW3|J3KNW3_HUMAN,tr|F8VZG9|F8VZG9_HUMAN,tr|J3QRF4|J3QRF4_HUMAN,tr|F8VRS4|F8VRS4_HUMAN,tr|A0A6Q8PFM4|A0A6Q8PFM4_HUMAN,tr|S4R469|S4R469_HUMAN,tr|A0A804HKG7|A0A804HKG7_HUMAN,tr|A0A0G2JRA5|A0A0G2JRA5_HUMAN,tr|A0A804HJM2|A0A804HJM2_HUMAN,tr|J3QQZ2|J3QQZ2_HUMAN,tr|I3L1D4|I3L1D4_HUMAN,tr|B0QYY7|B0QYY7_HUMAN,tr|A0A0G2JSB3|A0A0G2JSB3_HUMAN" 28 1081.6033 1.41 47987 13939 2 1081.60509 541.8089 RNA binding protein fox-1 homolog 2 OS=Homo sapiens OX=9606 GN=RBFOX2 PE=1 SV=3 9.76 2605.9 - 883139 - - - 1.6892 - 1.616 0.202 - 224.2 1 2 0 0.0018 9 0 0 0 3.20E+07 2.27E+07 - - - 1.9209 0.9943 221125_WJC_METTL3_EV_vs_WT_F04.13940.13940.3 0.672 Oct-36 K.K[136.11]EELTLEGIR[166.11].Q "sp|P60842|IF4A1_HUMAN,tr|J3KTB5|J3KTB5_HUMAN,tr|J3KT12|J3KT12_HUMAN,tr|J3QS69|J3QS69_HUMAN,tr|J3KTN0|J3KTN0_HUMAN,tr|J3KSZ0|J3KSZ0_HUMAN" 6 1204.6782 1.68 47988 13940 3 1204.674881 402.5667 Eukaryotic initiation factor 4A-I OS=Homo sapiens OX=9606 GN=EIF4A1 PE=1 SV=1 4.79 2606 - 563221 - - - -2.7734 - 1.866 0.228 - 143.2 1 2 0 -0.0033 10 0 0 0 4.22E+07 2.51E+07 - - - 2.9028 0.9936 221125_WJC_METTL3_EV_vs_WT_F04.13941.13941.2 4.81E-05 22-Dec F.QFGVSNLGQEEK.K sp|P49790|NU153_HUMAN 1 1334.6466 1.67 47989 13941 2 1334.647593 668.3306 Nuclear pore complex protein Nup153 OS=Homo sapiens OX=9606 GN=NUP153 PE=1 SV=2 4.53 2606.2 - 542245 - - - 0.711 - 2.234 0.576 - 561.9 1 1 0 0.0009 12 0 0 0 4.78E+06 2.86E+06 - - - 5.41 1 221125_WJC_METTL3_EV_vs_WT_F04.13945.13945.2 5.06E-07 24-Nov K.QADSVEQAVYYC[160.03]K.K "sp|Q9H2P0|ADNP_HUMAN,tr|A0A669KBJ7|A0A669KBJ7_HUMAN" 2 1559.6926 1.01 47993 13945 2 1559.692036 780.8536 Activity-dependent neuroprotector homeobox protein OS=Homo sapiens OX=9606 GN=ADNP PE=1 SV=1 4.37 2606.7 - 208039 - - - -0.3674 - 2.266 0.69 - 425.2 1 2 0 -0.0006 13 0 0 0 5.33E+06 5.27E+06 - - - 6.2366 0.9992 221125_WJC_METTL3_EV_vs_WT_F04.13949.13949.2 0.000437 26-Nov R.VAAALPGMESTQDR.S "sp|P20340|RAB6A_HUMAN,tr|F5H3K7|F5H3K7_HUMAN" 2 1444.698 1.47 47995 13949 2 1444.693629 723.3563 Ras-related protein Rab-6A OS=Homo sapiens OX=9606 GN=RAB6A PE=1 SV=3 4.37 2607.2 - 883129 - - - -3.0449 - 2.132 0.461 - 196.6 1 2 0 -0.0044 14 0 0 0 7.09E+07 4.84E+07 - - - 4.3444 0.9997 221125_WJC_METTL3_EV_vs_WT_F04.13950.13950.2 0.00241 13/22 R.GEPPLPEEDLSK[136.11].L "sp|O15372|EIF3H_HUMAN,tr|B3KS98|B3KS98_HUMAN,tr|A0A087WZK9|A0A087WZK9_HUMAN" 3 1317.6544 2.27 47996 13950 2 1317.652709 659.8345 Eukaryotic translation initiation factor 3 subunit H OS=Homo sapiens OX=9606 GN=EIF3H PE=1 SV=1 4 2607.3 - 4.21E+06 - - - -1.2545 - 2.118 0.397 - 437.9 1 2 0 -0.0017 12 0 0 0 3.25E+08 1.43E+08 - - - 3.9473 1 221125_WJC_METTL3_EV_vs_WT_F04.13952.13952.3 4.33E-07 18/52 K.VNPDLQVEVKPSIR.A sp|Q96KR1|ZFR_HUMAN 1 1592.8886 1.17 47998 13952 3 1592.886033 531.9701 Zinc finger RNA-binding protein OS=Homo sapiens OX=9606 GN=ZFR PE=1 SV=2 6.04 2607.4 - 1.10E+06 - - - -1.6153 - 2.965 0.579 - 448 1 2 0 -0.0026 14 0 0 0 2.84E+07 2.43E+07 - - - 7.883 1 221125_WJC_METTL3_EV_vs_WT_F04.13953.13953.3 4.78E-06 16/52 K.VNPDLQVEVK[136.11]PSIR[166.11].A sp|Q96KR1|ZFR_HUMAN 1 1610.9111 1.17 47999 13953 3 1610.908429 537.9776 Zinc finger RNA-binding protein OS=Homo sapiens OX=9606 GN=ZFR PE=1 SV=2 6.04 2607.6 - 900929 - - - -1.6432 - 3.11 0.501 - 468.8 1 2 0 -0.0026 14 0 0 0 2.84E+07 2.43E+07 - - - 7.1402 0.9319 221125_WJC_METTL3_EV_vs_WT_F04.13954.13954.2 0.879 16-Aug K.NWQYQETIK[136.11].K sp|Q15008|PSMD6_HUMAN 1 1216.5968 0.37 48000 13954 2 1216.600168 609.3057 26S proteasome non-ATPase regulatory subunit 6 OS=Homo sapiens OX=9606 GN=PSMD6 PE=1 SV=1 6 2607.7 - 701834 - - - 2.7782 - 1.231 0.078 - 222.8 1 2 0 0.0034 9 0 0 0 4.50E+06 1.21E+07 - - - 0.2173 0.9998 221125_WJC_METTL3_EV_vs_WT_F04.13955.13955.2 0.00113 13/28 R.LAC[160.03]LSEEGNEIESGK.L "sp|Q9Y2L1|RRP44_HUMAN,tr|F2Z2C0|F2Z2C0_HUMAN,tr|G3V1J5|G3V1J5_HUMAN" 3 1634.7458 1.75 48001 13955 2 1634.742764 818.3802 Exosome complex exonuclease RRP44 OS=Homo sapiens OX=9606 GN=DIS3 PE=1 SV=2 4.09 2607.8 - 646125 - - - -1.8364 - 2.63 0.531 - 553.7 1 2 0 -0.003 15 0 0 0 9.18E+07 5.25E+07 - - - 5.3394 0.9997 221125_WJC_METTL3_EV_vs_WT_F04.13958.13958.2 3.76E-07 24-Oct K.QADSVEQAVYYC[160.03]K[136.11].K "sp|Q9H2P0|ADNP_HUMAN,tr|A0A669KBJ7|A0A669KBJ7_HUMAN" 2 1567.7068 1.01 48004 13958 2 1567.70261 784.8607 Activity-dependent neuroprotector homeobox protein OS=Homo sapiens OX=9606 GN=ADNP PE=1 SV=1 4.37 2608.2 - 311485 - - - -2.6784 - 2.139 0.595 - 326.5 1 2 0 -0.0042 13 0 0 0 5.33E+06 5.27E+06 - - - 5.3858 0.9999 221125_WJC_METTL3_EV_vs_WT_F04.13960.13960.3 0.00035 Oct-32 R.KMVDQLFC[160.03]K.K "sp|P78347|GTF2I_HUMAN,tr|A0A494C0Q7|A0A494C0Q7_HUMAN,tr|A0A494C1K3|A0A494C1K3_HUMAN" 3 1167.578 1.27 48005 13960 3 1167.576457 390.2 General transcription factor II-I OS=Homo sapiens OX=9606 GN=GTF2I PE=1 SV=2 8.2 2608.4 - 2.24E+06 - - - -1.3524 - 2.038 0.432 - 201.2 1 2 0 -0.0016 9 0 0 0 4.46E+07 3.51E+07 - - - 5.5017 0.9992 221125_WJC_METTL3_EV_vs_WT_F04.13962.13962.3 1.44 Nov-36 K.KEELTLEGIR.Q "sp|P60842|IF4A1_HUMAN,tr|J3KTB5|J3KTB5_HUMAN,tr|J3KT12|J3KT12_HUMAN,tr|J3QS69|J3QS69_HUMAN,tr|J3KTN0|J3KTN0_HUMAN,tr|J3KSZ0|J3KSZ0_HUMAN" 6 1186.6558 1.69 48006 13962 3 1186.653493 396.5592 Eukaryotic initiation factor 4A-I OS=Homo sapiens OX=9606 GN=EIF4A1 PE=1 SV=1 4.79 2608.6 - 1.79E+06 - - - -1.9037 - 2.315 0.257 - 176.7 1 2 0 -0.0023 10 0 0 0 4.32E+07 2.56E+07 - - - 3.8561 0.999 221125_WJC_METTL3_EV_vs_WT_F04.13967.13967.2 0.0266 14-Sep K.KALWFQGR.C "sp|P43243|MATR3_HUMAN,tr|B3KM87|B3KM87_HUMAN,tr|A8MXP9|A8MXP9_HUMAN,tr|A0A0R4J2E8|A0A0R4J2E8_HUMAN,tr|H0Y8T4|H0Y8T4_HUMAN,tr|D6REM6|D6REM6_HUMAN" 6 1004.5556 1.28 48009 13967 2 1004.554756 503.2851 Matrin-3 OS=Homo sapiens OX=9606 GN=MATR3 PE=1 SV=2 11 2609.3 - 1.52E+06 - - - -0.8252 - 1.94 0.199 - 358.3 1 2 0 -0.0008 8 0 0 0 5.25E+07 4.11E+07 - - - 2.5092 0.9997 221125_WJC_METTL3_EV_vs_WT_F04.13968.13968.3 0.000665 13/60 R.MLTGPVYSQSTALTHK[136.11].Q "sp|Q86VP6|CAND1_HUMAN,tr|A0A0C4DGH5|A0A0C4DGH5_HUMAN" 2 1740.896 1.18 48010 13968 3 1740.894795 581.3059 Cullin-associated NEDD8-dissociated protein 1 OS=Homo sapiens OX=9606 GN=CAND1 PE=1 SV=2 8.37 2609.4 - 563950 - - - -0.6956 - 2.109 0.331 - 76.8 1 2 0 -0.0012 16 0 0 0 7.12E+06 6.04E+06 - - - 4.1447 0.9996 221125_WJC_METTL3_EV_vs_WT_F04.13970.13970.2 2.54E-05 26-Dec K.FEAGQFEPSETTAK.S sp|Q5JTJ3|COA6_HUMAN 1 1540.7046 0.01 48012 13970 2 1540.699683 771.3596 Cytochrome c oxidase assembly factor 6 homolog OS=Homo sapiens OX=9606 GN=COA6 PE=1 SV=1 4.25 2609.7 - 601224 - - - -3.1609 - 2.461 0.578 - 417.8 1 2 0 -0.0049 14 0 0 0 3.46E+07 2.66E+09 - - - 5.5685 0.795 221125_WJC_METTL3_EV_vs_WT_F04.13976.13976.3 0.0232 Aug-48 R.VIHLSNLPHSGYS.D "sp|P43243|MATR3_HUMAN,tr|B3KM87|B3KM87_HUMAN,tr|A8MXP9|A8MXP9_HUMAN,tr|D6RBK5|D6RBK5_HUMAN,tr|A0A0R4J2E8|A0A0R4J2E8_HUMAN,tr|H0Y8T4|H0Y8T4_HUMAN,tr|D6REM6|D6REM6_HUMAN" 7 1422.7256 - 48016 13976 3 1422.723598 475.2491 Matrin-3 OS=Homo sapiens OX=9606 GN=MATR3 PE=1 SV=2 6.89 2610.3 - 1.82E+06 - - - -1.3812 - 1.607 0.269 - 72.3 1 1 0 -0.002 13 0 0 0 - - - - - 2.8247 0.999 221125_WJC_METTL3_EV_vs_WT_F04.13978.13978.2 0.0221 24-Oct R.SLPTTVPESPNYR.N "sp|Q6PKG0|LARP1_HUMAN,tr|A0A0B4J210|A0A0B4J210_HUMAN,tr|H0YC33|H0YC33_HUMAN,tr|E5RH50|E5RH50_HUMAN" 4 1459.7307 1.06 48018 13978 2 1459.728357 730.8726 La-related protein 1 OS=Homo sapiens OX=9606 GN=LARP1 PE=1 SV=2 5.72 2610.6 - 953029 - - - -1.6106 - 1.857 0.302 - 195.9 1 2 0 -0.0024 13 0 0 0 2.00E+07 1.88E+07 - - - 2.8594 0.9795 221125_WJC_METTL3_EV_vs_WT_F04.13979.13979.3 0.14 Sep-40 K.YDLSGRPLNIK.E "sp|Q9P2K5|MYEF2_HUMAN,tr|A0A0A0MR39|A0A0A0MR39_HUMAN,tr|A0A087WUT0|A0A087WUT0_HUMAN,tr|A0A0A0MQW0|A0A0A0MQW0_HUMAN" 4 1274.6983 1.52 48019 13979 3 1274.694878 425.9067 Myelin expression factor 2 OS=Homo sapiens OX=9606 GN=MYEF2 PE=1 SV=3 8.59 2610.7 - 786966 - - - -2.6736 - 1.571 0.197 - 59.2 1 2 0 -0.0034 11 0 0 0 3.53E+07 2.33E+07 - - - 2.0186 1 221125_WJC_METTL3_EV_vs_WT_F04.13981.13981.3 1.18E-07 13/48 R.YFC[160.03]HC[160.03]C[160.03]SVEIVPR.L "sp|Q9BV68|RN126_HUMAN,tr|U3KQF4|U3KQF4_HUMAN,tr|K7EIY6|K7EIY6_HUMAN" 3 1725.7426 1.81 48021 13981 3 1725.738617 576.2548 E3 ubiquitin-protein ligase RNF126 OS=Homo sapiens OX=9606 GN=RNF126 PE=1 SV=2 6.72 2610.9 - 773072 - - - -2.2808 - 2.401 0.664 - 196.7 1 2 0 -0.0039 13 0 0 0 1.37E+07 7.57E+06 - - - 8.3166 1 221125_WJC_METTL3_EV_vs_WT_F04.13982.13982.3 2.67E-07 13/48 R.YFC[160.03]HC[160.03]C[160.03]SVEIVPR[166.11].L "sp|Q9BV68|RN126_HUMAN,tr|U3KQF4|U3KQF4_HUMAN,tr|K7EIY6|K7EIY6_HUMAN" 3 1735.7508 1.83 48022 13982 3 1735.749731 579.5909 E3 ubiquitin-protein ligase RNF126 OS=Homo sapiens OX=9606 GN=RNF126 PE=1 SV=2 6.72 2611.1 - 632608 - - - -0.6291 - 2.246 0.65 - 201.5 1 2 0 -0.0011 13 0 0 0 1.37E+07 7.49E+06 - - - 7.9804 0.999 221125_WJC_METTL3_EV_vs_WT_F04.13986.13986.2 0.00134 26-Nov R.VAAALPGMESTQDR[166.11].S "sp|P20340|RAB6A_HUMAN,tr|F5H3K7|F5H3K7_HUMAN" 2 1454.7063 1.46 48024 13986 2 1454.701938 728.3604 Ras-related protein Rab-6A OS=Homo sapiens OX=9606 GN=RAB6A PE=1 SV=3 4.37 2611.6 - 1.85E+06 - - - -2.9972 - 2.166 0.394 - 272.2 1 2 0 -0.0044 14 0 0 0 7.08E+07 4.84E+07 - - - 3.8892 0.999 221125_WJC_METTL3_EV_vs_WT_F04.13989.13989.3 0.0193 Oct-40 K.YDLSGR[166.11]PLNIK[136.11].E "sp|Q9P2K5|MYEF2_HUMAN,tr|A0A0A0MR39|A0A0A0MR39_HUMAN,tr|A0A087WUT0|A0A087WUT0_HUMAN,tr|A0A0A0MQW0|A0A0A0MQW0_HUMAN" 4 1292.7208 1.52 48027 13989 3 1292.719962 431.9142 Myelin expression factor 2 OS=Homo sapiens OX=9606 GN=MYEF2 PE=1 SV=3 8.59 2611.9 - 907505 - - - -0.6142 - 1.806 0.276 - 69.2 1 2 0 -0.0008 11 0 0 0 3.54E+07 2.33E+07 - - - 3.2962 0.9996 221125_WJC_METTL3_EV_vs_WT_F04.13990.13990.3 0.0103 15/40 K.TAITVEHLAIK.C sp|Q9NR30|DDX21_HUMAN 1 1194.6972 0.51 48028 13990 3 1194.694313 399.2397 Nucleolar RNA helicase 2 OS=Homo sapiens OX=9606 GN=DDX21 PE=1 SV=5 6.41 2612 - 832865 - - - -2.4358 - 2.625 0.304 - 217.5 1 2 0 -0.0029 11 0 0 0 1.17E+07 2.28E+07 - - - 4.6701 1 221125_WJC_METTL3_EV_vs_WT_F04.13995.13995.2 6.63E-08 15/24 K.EITEGDEVEVYSR.A "sp|P51116|FXR2_HUMAN,tr|I3L1Z2|I3L1Z2_HUMAN" 2 1524.6944 0.69 48031 13995 2 1524.691802 763.3545 Fragile X mental retardation syndrome-related protein 2 OS=Homo sapiens OX=9606 GN=FXR2 PE=1 SV=2 3.91 2612.7 - 1.17E+06 - - - -1.6928 - 2.652 0.591 - 848.9 1 2 0 -0.0026 13 0 0 0 1.75E+07 2.53E+07 - - - 5.9085 0.9998 221125_WJC_METTL3_EV_vs_WT_F04.13998.13998.3 0.000152 16/40 R.VVDLMAHMASK[136.11].E "sp|P04406|G3P_HUMAN,tr|E7EUT5|E7EUT5_HUMAN" 2 1208.6137 0.94 48034 13998 3 1208.611486 403.8785 Glyceraldehyde-3-phosphate dehydrogenase OS=Homo sapiens OX=9606 GN=GAPDH PE=1 SV=3 6.71 2613 - 1.26E+06 - - - -1.8319 - 2.348 0.37 - 299.2 1 2 0 -0.0022 11 0 0 0 4.09E+07 4.36E+07 - - - 5.0894 0.9994 221125_WJC_METTL3_EV_vs_WT_F04.13999.13999.2 0.0101 18-Oct R.NSLPDTVQIR.R "sp|P56537|IF6_HUMAN,tr|B7ZBH1|B7ZBH1_HUMAN" 2 1141.6091 1.17 48035 13999 2 1141.606703 571.8118 Eukaryotic translation initiation factor 6 OS=Homo sapiens OX=9606 GN=EIF6 PE=1 SV=1 5.84 2613.1 - 1.23E+06 - - - -2.1321 - 2.137 0.345 - 373.9 1 2 0 -0.0024 10 0 0 0 3.05E+07 2.60E+07 - - - 3.7081 0.9996 221125_WJC_METTL3_EV_vs_WT_F04.14002.14002.2 0.00039 20-Aug K.NPNGPYPYTLK.L "sp|P14866|HNRPL_HUMAN,tr|A0A3B3ITJ4|A0A3B3ITJ4_HUMAN,tr|M0QXS5|M0QXS5_HUMAN" 3 1262.6295 1.2 48038 14002 2 1262.632245 632.322 Heterogeneous nuclear ribonucleoprotein L OS=Homo sapiens OX=9606 GN=HNRNPL PE=1 SV=2 8.5 2613.5 - 513006 - - - 2.1439 - 1.955 0.502 - 218.9 1 2 0 0.0027 11 0 0 0 1.02E+07 8.47E+06 - - - 4.5615 0.9994 221125_WJC_METTL3_EV_vs_WT_F04.14003.14003.2 2.99E-07 20-Oct K.NPNGPYPYTLK[136.11].L "sp|P14866|HNRPL_HUMAN,tr|A0A3B3ITJ4|A0A3B3ITJ4_HUMAN,tr|M0QXS5|M0QXS5_HUMAN" 3 1270.6437 1.2 48039 14003 2 1270.639757 636.3291 Heterogeneous nuclear ribonucleoprotein L OS=Homo sapiens OX=9606 GN=HNRNPL PE=1 SV=2 8.5 2613.6 - 466242 - - - -3.1331 - 2.173 0.521 - 430.9 1 2 0 -0.004 11 0 0 0 1.02E+07 8.47E+06 - - - 4.9874 0.999 221125_WJC_METTL3_EV_vs_WT_F04.14005.14005.3 0.00176 Oct-40 K.GLEISGTFTHR.Q "sp|P63010|AP2B1_HUMAN,tr|A0A087X253|A0A087X253_HUMAN" 2 1216.62 0.94 48041 14005 3 1216.61648 406.5473 AP-2 complex subunit beta OS=Homo sapiens OX=9606 GN=AP2B1 PE=1 SV=1 6.75 2613.8 - 243209 - - - -2.9229 - 2.149 0.319 - 91.6 1 2 0 -0.0036 11 0 0 0 2.73E+06 2.90E+06 - - - 4.2688 1 221125_WJC_METTL3_EV_vs_WT_F04.14006.14006.2 1.58E-07 14/30 K.LSEEVVVAPNQESGMK.T "sp|Q6PJT7|ZC3HE_HUMAN,tr|G3V4R5|G3V4R5_HUMAN,tr|H0YJA2|H0YJA2_HUMAN,tr|G3V411|G3V411_HUMAN" 4 1715.84 2.05 48042 14006 2 1715.83993 858.9273 Zinc finger CCCH domain-containing protein 14 OS=Homo sapiens OX=9606 GN=ZC3H14 PE=1 SV=1 4.25 2614 - 317406 - - - -0.0414 - 2.948 0.637 - 504.7 1 2 0 -0.0001 16 0 0 0 3.37E+06 1.65E+06 - - - 6.4039 0.9996 221125_WJC_METTL3_EV_vs_WT_F04.14008.14008.3 1.40E-05 14/40 K.TRLEQEIATYR.R "sp|Q04695|K1C17_HUMAN,sp|P02533|K1C14_HUMAN,sp|P35900|K1C20_HUMAN,sp|P08779|K1C16_HUMAN,sp|P19012|K1C15_HUMAN,sp|P13646|K1C13_HUMAN,tr|A0A3B3IS58|A0A3B3IS58_HUMAN,tr|F5GWP8|F5GWP8_HUMAN,tr|K7ERE3|K7ERE3_HUMAN,tr|A8MT21|A8MT21_HUMAN" 10 1378.7205 290.14 48043 14008 3 1378.718653 460.5808 "Keratin, type I cytoskeletal 17 OS=Homo sapiens OX=9606 GN=KRT17 PE=1 SV=2" 5.81 2614.2 - 4.06E+07 - - - -1.3237 - 2.906 0.359 - 398.7 1 2 1 -0.0018 11 0 0 0 1.05E+09 3.62E+06 - - - 5.5725 0.9967 221125_WJC_METTL3_EV_vs_WT_F04.14009.14009.2 6.56E-05 24-Oct R.SGSTAVGVMISPK.H "sp|O75688|PPM1B_HUMAN,tr|B8ZZF0|B8ZZF0_HUMAN,tr|A0A3B3IS24|A0A3B3IS24_HUMAN,tr|C9JIR6|C9JIR6_HUMAN" 4 1232.6435 3.14 48044 14009 2 1232.643095 617.329 Protein phosphatase 1B OS=Homo sapiens OX=9606 GN=PPM1B PE=1 SV=1 8.47 2614.3 - 721910 - - - -0.3067 - 2.054 0.089 - 305 2 2 0 -0.0004 13 0 0 0 5.74E+08 1.83E+08 - - - 1.4111 0.9999 221125_WJC_METTL3_EV_vs_WT_F04.14010.14010.3 0.00128 14/40 K.VTLEYR[166.11]PVIDK[136.11].T "sp|P31040|SDHA_HUMAN,tr|A0A087X1I3|A0A087X1I3_HUMAN,tr|D6RFM5|D6RFM5_HUMAN" 3 1349.7674 0.56 48045 14010 3 1349.765445 450.9297 "Succinate dehydrogenase [ubiquinone] flavoprotein subunit, mitochondrial OS=Homo sapiens OX=9606 GN=SDHA PE=1 SV=2" 6.04 2614.4 - 1.84E+06 - - - -1.4277 - 2.892 0.32 - 327.9 1 2 0 -0.0019 11 0 0 0 2.43E+07 4.31E+07 - - - 5.124 0.9997 221125_WJC_METTL3_EV_vs_WT_F04.14012.14012.2 0.0217 18-Nov R.NSLPDTVQIR[166.11].R "sp|P56537|IF6_HUMAN,tr|B7ZBH1|B7ZBH1_HUMAN" 2 1151.6174 1.3 48047 14012 2 1151.618414 576.816 Eukaryotic translation initiation factor 6 OS=Homo sapiens OX=9606 GN=EIF6 PE=1 SV=1 5.84 2614.6 - 991236 - - - 0.8744 - 1.929 0.391 - 458 1 2 0 0.001 10 0 0 0 2.88E+07 2.22E+07 - - - 3.7625 0.9996 221125_WJC_METTL3_EV_vs_WT_F04.14013.14013.2 2.83E-05 18-Sep R.ESYDDVSSFR.A "sp|Q99848|EBP2_HUMAN,tr|H7C2Q8|H7C2Q8_HUMAN" 2 1203.5044 1.15 48048 14013 2 1203.501969 602.7595 Probable rRNA-processing protein EBP2 OS=Homo sapiens OX=9606 GN=EBNA1BP2 PE=1 SV=2 4.03 2614.8 - 909346 - - - -2.0174 - 1.919 0.473 - 216.1 1 2 0 -0.0024 10 0 0 0 8.96E+06 7.80E+06 - - - 4.3532 1 221125_WJC_METTL3_EV_vs_WT_F04.14015.14015.2 1.54E-06 13/16 R.HGSLGFLPR.K "sp|P39023|RL3_HUMAN,tr|H7C3M2|H7C3M2_HUMAN,tr|F8WCR1|F8WCR1_HUMAN,tr|H7C422|H7C422_HUMAN" 4 982.5348 0.76 48050 14015 2 982.534392 492.2747 60S ribosomal protein L3 OS=Homo sapiens OX=9606 GN=RPL3 PE=1 SV=2 9.76 2615 - 641621 - - - -0.4651 - 2.644 0.55 - 481.8 1 2 0 -0.0005 9 0 0 0 2.20E+07 2.88E+07 - - - 5.9161 0.9999 221125_WJC_METTL3_EV_vs_WT_F04.14018.14018.2 5.09E-05 22-Nov R.TWNDPSVQQDIK.F "sp|P11021|BIP_HUMAN,tr|A0A7P0TB36|A0A7P0TB36_HUMAN,tr|A0A7P0TAI0|A0A7P0TAI0_HUMAN" 3 1429.6838 0.55 48051 14018 2 1429.682192 715.8492 Endoplasmic reticulum chaperone BiP OS=Homo sapiens OX=9606 GN=HSPA5 PE=1 SV=2 4.21 2615.4 - 9.34E+06 - - - -1.0953 - 2.439 0.547 - 325.3 1 2 0 -0.0016 12 0 0 0 1.14E+08 2.08E+08 - - - 5.4266 0.9916 221125_WJC_METTL3_EV_vs_WT_F04.14019.14019.2 9.86E-05 24-Oct K.IELFGR[166.11]PHNVQPN.W sp|Q86U44|MTA70_HUMAN 1 1529.7978 0.001 48052 14019 2 1529.797517 765.9062 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 6.75 2615.5 - 4.65E+06 - - - -0.2053 - 2.109 0.491 - 215.6 1 1 0 -0.0003 13 0 0 0 0.00E+00 8.03E+07 - - - 4.5826 0.9985 221125_WJC_METTL3_EV_vs_WT_F04.14020.14020.2 2.52E-08 24-Nov K.EITEGDEVEVYSR[166.11].A "sp|P51116|FXR2_HUMAN,tr|I3L1Z2|I3L1Z2_HUMAN" 2 1534.7027 0.62 48053 14020 2 1534.695298 768.3586 Fragile X mental retardation syndrome-related protein 2 OS=Homo sapiens OX=9606 GN=FXR2 PE=1 SV=2 3.91 2615.6 - 1.93E+06 - - - -4.7925 - 2.5 0.549 - 392.7 1 2 0 -0.0074 13 0 0 0 1.75E+07 2.81E+07 - - - 5.4453 0.9999 221125_WJC_METTL3_EV_vs_WT_F04.14021.14021.3 9.31E-05 14/64 K.SLYVAEYHSEPVEDEKP.- sp|P26196|DDX6_HUMAN 1 1990.916 0.83 48054 14021 3 1990.913936 664.6459 Probable ATP-dependent RNA helicase DDX6 OS=Homo sapiens OX=9606 GN=DDX6 PE=1 SV=2 4.25 2615.7 - 1.30E+06 - - - -1.0382 - 2.079 0.444 - 84.2 1 2 0 -0.0021 17 0 0 0 1.48E+07 1.79E+07 - - - 5.3386 0.9946 221125_WJC_METTL3_EV_vs_WT_F04.14022.14022.3 0.503 Nov-44 K.WGDEHIPGSPYR.V "sp|P21333|FLNA_HUMAN,tr|A0A7P0NMY4|A0A7P0NMY4_HUMAN,tr|Q60FE5|Q60FE5_HUMAN" 3 1412.6473 0.99 48055 14022 3 1412.642541 471.8897 Filamin-A OS=Homo sapiens OX=9606 GN=FLNA PE=1 SV=4 5.32 2615.8 - 1.28E+06 - - - -3.3781 - 1.668 0.295 - 135.6 1 2 0 -0.0048 12 0 0 0 1.59E+07 1.60E+07 - - - 3.2458 0.9999 221125_WJC_METTL3_EV_vs_WT_F04.14023.14023.3 0.176 14/40 K.VTLEYRPVIDK.T "sp|P31040|SDHA_HUMAN,tr|A0A087X1I3|A0A087X1I3_HUMAN,tr|D6RFM5|D6RFM5_HUMAN" 3 1331.7449 0.51 48056 14023 3 1331.746096 444.9222 "Succinate dehydrogenase [ubiquinone] flavoprotein subunit, mitochondrial OS=Homo sapiens OX=9606 GN=SDHA PE=1 SV=2" 6.04 2615.9 - 1.24E+06 - - - 0.8966 - 2.559 0.336 - 298 1 2 0 0.0012 11 0 0 0 2.19E+07 4.27E+07 - - - 4.955 0.9981 221125_WJC_METTL3_EV_vs_WT_F04.14024.14024.3 0.023 Sep-44 K.WGDEHIPGSPYR[166.11].V "sp|P21333|FLNA_HUMAN,tr|A0A7P0NMY4|A0A7P0NMY4_HUMAN,tr|Q60FE5|Q60FE5_HUMAN" 3 1422.6556 0.99 48057 14024 3 1422.654806 475.2258 Filamin-A OS=Homo sapiens OX=9606 GN=FLNA PE=1 SV=4 5.32 2616 - 1.19E+06 - - - -0.5462 - 1.551 0.278 - 97.5 1 2 0 -0.0008 12 0 0 0 1.58E+07 1.60E+07 - - - 2.8558 0.9939 221125_WJC_METTL3_EV_vs_WT_F04.14027.14027.3 1.01E-05 15/44 R.LRPEPC[160.03]ISLEPR.P sp|Q5T749|KPRP_HUMAN 1 1465.7711 1.26 48060 14027 3 1465.76834 489.5977 Keratinocyte proline-rich protein OS=Homo sapiens OX=9606 GN=KPRP PE=1 SV=1 6.14 2616.4 - 642722 - - - -1.9062 - 2.361 0.486 - 429.7 1 1 0 -0.0028 12 0 0 0 2.65E+07 2.11E+07 - - - 6.3389 0.9999 221125_WJC_METTL3_EV_vs_WT_F04.14028.14028.2 4.21E-06 22-Nov R.FLEQQNQVLQTK.W "sp|Q7Z794|K2C1B_HUMAN,sp|P04264|K2C1_HUMAN,sp|P35908|K22E_HUMAN" 3 1474.778 999 48061 14028 2 1474.778545 738.3963 "Keratin, type II cytoskeletal 1b OS=Homo sapiens OX=9606 GN=KRT77 PE=1 SV=3" 6 2616.5 - 615529 - - - 0.3743 - 2.315 0.541 - 347.5 1 2 0 0.0006 12 0 0 0 2.45E+07 0.00E+00 - - - 5.2453 0.9988 221125_WJC_METTL3_EV_vs_WT_F04.14031.14031.3 0.0271 Dec-52 R.VAAALPGMESTQDR[166.11].S "sp|P20340|RAB6A_HUMAN,tr|F5H3K7|F5H3K7_HUMAN" 2 1454.7063 0.8 48064 14031 3 1454.703902 485.9094 Ras-related protein Rab-6A OS=Homo sapiens OX=9606 GN=RAB6A PE=1 SV=3 4.37 2616.9 - 201239 - - - -1.6471 - 2.041 0.271 - 170.8 1 2 0 -0.0024 14 0 0 0 6.96E+06 8.74E+06 - - - 3.4567 1 221125_WJC_METTL3_EV_vs_WT_F04.14034.14034.3 0.000694 Nov-40 R.VVDLMAHMASK.E "sp|P04406|G3P_HUMAN,tr|E7EUT5|E7EUT5_HUMAN" 2 1200.5995 0.94 48065 14034 3 1200.597648 401.2071 Glyceraldehyde-3-phosphate dehydrogenase OS=Homo sapiens OX=9606 GN=GAPDH PE=1 SV=3 6.71 2617.3 - 4.08E+06 - - - -1.5426 - 1.927 0.534 - 123.4 1 2 0 -0.0019 11 0 0 0 4.09E+07 4.36E+07 - - - 6.3565 0.9999 221125_WJC_METTL3_EV_vs_WT_F04.14036.14036.3 4.57E-07 16/52 K.AIVIC[160.03]PTDEDLKDR.T "sp|Q9BUJ2|HNRL1_HUMAN,tr|A0A0A0MRA5|A0A0A0MRA5_HUMAN,tr|M0R3F1|M0R3F1_HUMAN,tr|B7Z4B8|B7Z4B8_HUMAN" 4 1643.8189 1.43 48067 14036 3 1643.816756 548.9469 Heterogeneous nuclear ribonucleoprotein U-like protein 1 OS=Homo sapiens OX=9606 GN=HNRNPUL1 PE=1 SV=2 4.23 2617.4 - 2.46E+06 - - - -1.2872 - 2.65 0.495 - 359.5 1 2 1 -0.0021 14 0 0 0 4.10E+07 2.86E+07 - - - 6.6481 0.9999 221125_WJC_METTL3_EV_vs_WT_F04.14038.14038.3 0.000328 17/52 K.AIVIC[160.03]PTDEDLK[136.11]DR[166.11].T "sp|Q9BUJ2|HNRL1_HUMAN,tr|A0A0A0MRA5|A0A0A0MRA5_HUMAN,tr|M0R3F1|M0R3F1_HUMAN,tr|B7Z4B8|B7Z4B8_HUMAN" 4 1661.8413 1.41 48069 14038 3 1661.839978 554.9544 Heterogeneous nuclear ribonucleoprotein U-like protein 1 OS=Homo sapiens OX=9606 GN=HNRNPUL1 PE=1 SV=2 4.23 2617.6 - 1.34E+06 - - - -0.8208 - 3.254 0.44 - 475.6 1 2 1 -0.0014 14 0 0 0 4.13E+07 2.93E+07 - - - 6.5808 0.9921 221125_WJC_METTL3_EV_vs_WT_F04.14039.14039.3 0.128 Oct-40 R.LFDQPGDPLKR.S sp|Q96EY7|PTCD3_HUMAN 1 1284.6826 1.6 48070 14039 3 1284.682848 429.2348 "Pentatricopeptide repeat domain-containing protein 3, mitochondrial OS=Homo sapiens OX=9606 GN=PTCD3 PE=1 SV=3" 5.96 2617.7 - 858606 - - - 0.165 - 1.412 0.218 - 124.3 1 2 0 0.0002 11 0 0 0 4.34E+07 2.71E+07 - - - 1.9505 0.9999 221125_WJC_METTL3_EV_vs_WT_F04.14042.14042.3 7.12E-05 Dec-44 K.LHPEMSNLDLTK.L "sp|P17480|UBF1_HUMAN,tr|E9PMM2|E9PMM2_HUMAN,tr|E9PKP7|E9PKP7_HUMAN" 3 1396.7021 1.49 48073 14042 3 1396.699813 466.5746 Nucleolar transcription factor 1 OS=Homo sapiens OX=9606 GN=UBTF PE=1 SV=1 5.32 2618.1 - 492101 - - - -1.6023 - 2.428 0.414 - 242.5 1 2 0 -0.0022 12 0 0 0 1.56E+07 1.05E+07 - - - 5.6139 0.9993 221125_WJC_METTL3_EV_vs_WT_F04.14047.14047.3 1.44E-05 13/36 R.DETEFYLGKR.C "sp|P18077|RL35A_HUMAN,tr|F8WB72|F8WB72_HUMAN,tr|C9K025|C9K025_HUMAN,tr|F8WBS5|F8WBS5_HUMAN" 4 1256.6037 1.05 48076 14047 3 1256.601959 419.8752 60S ribosomal protein L35a OS=Homo sapiens OX=9606 GN=RPL35A PE=1 SV=2 4.68 2618.8 - 1.44E+06 - - - -1.399 - 2.027 0.279 - 401.4 1 2 0 -0.0018 10 0 0 0 1.78E+07 1.69E+07 - - - 3.7135 0.9999 221125_WJC_METTL3_EV_vs_WT_F04.14048.14048.2 8.03E-05 18-Sep K.NGQDLGVAFK[136.11].L "sp|Q00839|HNRPU_HUMAN,tr|A0A1W2PQL0|A0A1W2PQL0_HUMAN,tr|A0A1W2PPL4|A0A1W2PPL4_HUMAN,tr|A0A1W2PQ74|A0A1W2PQ74_HUMAN,tr|Q5RI18|Q5RI18_HUMAN,tr|A0A1W2PP35|A0A1W2PP35_HUMAN,tr|A0A1W2PPS1|A0A1W2PPS1_HUMAN,tr|A0A1W2PRZ7|A0A1W2PRZ7_HUMAN,tr|A0A1W2PPH7|A0A1W2PPH7_HUMAN,tr|A0A1W2PP34|A0A1W2PP34_HUMAN,tr|A0A1X7SBS1|A0A1X7SBS1_HUMAN" 11 1055.5491 0.96 48077 14048 2 1055.548821 528.7818 Heterogeneous nuclear ribonucleoprotein U OS=Homo sapiens OX=9606 GN=HNRNPU PE=1 SV=6 5.84 2618.8 - 2.12E+06 - - - -0.2728 - 2.135 0.463 - 367.2 1 2 0 -0.0003 10 0 0 0 1.04E+08 1.08E+08 - - - 4.5777 0.9978 221125_WJC_METTL3_EV_vs_WT_F04.14049.14049.3 0.000403 Nov-44 M.VYMFQYDSTHGK[136.11].F sp|P04406|G3P_HUMAN 1 1482.6693 0.81 48078 14049 3 1482.670051 495.2304 Glyceraldehyde-3-phosphate dehydrogenase OS=Homo sapiens OX=9606 GN=GAPDH PE=1 SV=3 6.71 2618.9 - 1.80E+06 - - - 0.5058 - 2.049 0.577 - 130 1 1 0 0.0008 12 0 0 0 2.34E+07 2.89E+07 - - - 6.9612 0.9999 221125_WJC_METTL3_EV_vs_WT_F04.14050.14050.3 5.48E-06 Dec-44 K.LHPEMSNLDLTK[136.11].L "sp|P17480|UBF1_HUMAN,tr|E9PMM2|E9PMM2_HUMAN,tr|E9PKP7|E9PKP7_HUMAN" 3 1404.7163 1.49 48079 14050 3 1404.717235 469.246 Nucleolar transcription factor 1 OS=Homo sapiens OX=9606 GN=UBTF PE=1 SV=1 5.32 2619.1 - 892197 - - - 0.7005 - 2.623 0.352 - 242.7 1 2 0 0.001 12 0 0 0 1.56E+07 1.05E+07 - - - 5.1371 0.9987 221125_WJC_METTL3_EV_vs_WT_F04.14053.14053.2 0.0199 22-Aug R.DGNIQEGDVVLK[136.11].L "sp|Q07157|ZO1_HUMAN,tr|A0A087X0K9|A0A087X0K9_HUMAN,tr|G5E9E7|G5E9E7_HUMAN,tr|A0A0G2JNH2|A0A0G2JNH2_HUMAN,tr|H0YKB1|H0YKB1_HUMAN,tr|G3V1L9|G3V1L9_HUMAN,tr|A0A7I2V5U5|A0A7I2V5U5_HUMAN" 7 1293.6656 0.27 48082 14053 2 1293.668268 647.8401 Tight junction protein ZO-1 OS=Homo sapiens OX=9606 GN=TJP1 PE=1 SV=3 4.03 2619.4 - 627108 - - - 2.0662 - 1.664 0.349 - 206.1 1 2 0 0.0027 12 0 0 0 6.87E+06 2.51E+07 - - - 2.9577 0.9993 221125_WJC_METTL3_EV_vs_WT_F04.14054.14054.2 1.00E-05 22-Oct R.DGNIQEGDVVLK.L "sp|Q07157|ZO1_HUMAN,tr|A0A087X0K9|A0A087X0K9_HUMAN,tr|G5E9E7|G5E9E7_HUMAN,tr|A0A0G2JNH2|A0A0G2JNH2_HUMAN,tr|H0YKB1|H0YKB1_HUMAN,tr|G3V1L9|G3V1L9_HUMAN,tr|A0A7I2V5U5|A0A7I2V5U5_HUMAN" 7 1285.6514 0.29 48083 14054 2 1285.655232 643.833 Tight junction protein ZO-1 OS=Homo sapiens OX=9606 GN=TJP1 PE=1 SV=3 4.03 2619.6 - 410359 - - - 2.9845 - 2.033 0.493 - 392.3 1 2 0 0.0038 12 0 0 0 6.87E+06 2.40E+07 - - - 4.5479 0.9999 221125_WJC_METTL3_EV_vs_WT_F04.14057.14057.3 9.36E-07 13/40 K.IRLENEIQTYR.S "sp|P13645|K1C10_HUMAN,tr|A0A1B0GVI3|A0A1B0GVI3_HUMAN" 2 1433.7627 5640.75 48085 14057 3 1433.762052 478.9282 "Keratin, type I cytoskeletal 10 OS=Homo sapiens OX=9606 GN=KRT10 PE=1 SV=6" 6.14 2619.9 - 1.36E+07 - - - -0.4359 - 2.714 0.521 - 325.8 1 2 1 -0.0006 11 0 0 0 5.02E+09 8.90E+05 - - - 7.1848 0.9895 221125_WJC_METTL3_EV_vs_WT_F04.14059.14059.3 0.00423 Oct-36 R.DETEFYLGK[136.11]R[166.11].C "sp|P18077|RL35A_HUMAN,tr|F8WB72|F8WB72_HUMAN,tr|C9K025|C9K025_HUMAN,tr|F8WBS5|F8WBS5_HUMAN" 4 1274.6262 1.14 48086 14059 3 1274.625327 425.8827 60S ribosomal protein L35a OS=Homo sapiens OX=9606 GN=RPL35A PE=1 SV=2 4.68 2620.1 - 2.10E+06 - - - -0.6747 - 1.505 0.183 - 111.1 1 2 0 -0.0009 10 0 0 0 1.56E+07 1.37E+07 - - - 1.7739 0.9872 221125_WJC_METTL3_EV_vs_WT_F04.14060.14060.3 0.000292 Sep-44 M.VYMFQYDSTHGK.F sp|P04406|G3P_HUMAN 1 1474.6551 0.77 48087 14060 3 1474.6556 492.559 Glyceraldehyde-3-phosphate dehydrogenase OS=Homo sapiens OX=9606 GN=GAPDH PE=1 SV=3 6.71 2620.2 - 1.53E+06 - - - 0.3384 - 1.577 0.466 - 63.9 1 1 0 0.0005 12 0 0 0 2.35E+07 3.07E+07 - - - 4.9979 0.9998 221125_WJC_METTL3_EV_vs_WT_F04.14061.14061.2 0.0138 16-Nov R.HGSLGFLPR[166.11].K "sp|P39023|RL3_HUMAN,tr|H7C3M2|H7C3M2_HUMAN,tr|F8WCR1|F8WCR1_HUMAN,tr|H7C422|H7C422_HUMAN" 4 992.5431 0.86 48088 14061 2 992.543327 497.2788 60S ribosomal protein L3 OS=Homo sapiens OX=9606 GN=RPL3 PE=1 SV=2 9.76 2620.3 - 1.56E+06 - - - 0.2096 - 1.978 0.409 - 297.8 1 2 0 0.0002 9 0 0 0 2.10E+07 2.44E+07 - - - 4.0351 0.9999 221125_WJC_METTL3_EV_vs_WT_F04.14063.14063.2 0.00672 13/22 R.QLDEGEISTIDK[136.11].V sp|P13674|P4HA1_HUMAN 1 1354.6707 1.9 48090 14063 2 1354.671118 678.3426 Prolyl 4-hydroxylase subunit alpha-1 OS=Homo sapiens OX=9606 GN=P4HA1 PE=1 SV=2 3.92 2620.6 - 1.12E+06 - - - 0.279 - 2.646 0.458 - 799.2 1 2 0 0.0004 12 0 0 0 4.49E+07 2.36E+07 - - - 4.9839 1 221125_WJC_METTL3_EV_vs_WT_F04.14064.14064.3 9.77E-07 13/64 R.GLIPAGTQHSMIATTGK.M "sp|Q9Y520|PRC2C_HUMAN,tr|E7EPN9|E7EPN9_HUMAN,tr|A0A2R8Y424|A0A2R8Y424_HUMAN,tr|H7C5N8|H7C5N8_HUMAN,tr|A0A2R8Y7F4|A0A2R8Y7F4_HUMAN,tr|A0A2R8YET2|A0A2R8YET2_HUMAN" 6 1681.8821 2.13 48091 14064 3 1681.883641 561.6347 Protein PRRC2C OS=Homo sapiens OX=9606 GN=PRRC2C PE=1 SV=4 8.76 2620.6 - 906809 - - - 0.8925 - 2.672 0.495 - 276.9 1 2 0 0.0015 17 0 0 0 1.25E+07 5.87E+06 - - - 6.5413 0.9998 221125_WJC_METTL3_EV_vs_WT_F04.14065.14065.2 0.000788 20-Dec R.ETVNALISDQK.L "sp|Q7LBC6|KDM3B_HUMAN,tr|H0Y9V5|H0Y9V5_HUMAN" 2 1216.6299 1.69 48092 14065 2 1216.6305 609.3222 Lysine-specific demethylase 3B OS=Homo sapiens OX=9606 GN=KDM3B PE=1 SV=2 4.37 2620.8 - 610296 - - - 0.4669 - 2.216 0.455 - 742.2 1 2 0 0.0006 11 0 0 0 8.09E+06 4.78E+06 - - - 4.554 0.9999 221125_WJC_METTL3_EV_vs_WT_F04.14066.14066.2 0.00146 20-Dec R.ETVNALISDQK[136.11].L "sp|Q7LBC6|KDM3B_HUMAN,tr|H0Y9V5|H0Y9V5_HUMAN" 2 1224.6441 1.69 48093 14066 2 1224.643244 613.3293 Lysine-specific demethylase 3B OS=Homo sapiens OX=9606 GN=KDM3B PE=1 SV=2 4.37 2620.9 - 600417 - - - -0.7251 - 2.349 0.481 - 644.2 1 2 0 -0.0009 11 0 0 0 8.09E+06 4.78E+06 - - - 4.9036 0.9996 221125_WJC_METTL3_EV_vs_WT_F04.14069.14069.2 2.80E-06 24-Dec K.EVSEEQPVVTLEK[136.11].Q "sp|P49321|NASP_HUMAN,tr|E9PPR5|E9PPR5_HUMAN" 2 1493.7705 0.81 48096 14069 2 1493.774126 747.8925 Nuclear autoantigenic sperm protein OS=Homo sapiens OX=9606 GN=NASP PE=1 SV=2 4.09 2621.3 - 543595 - - - 2.4582 - 2.143 0.507 - 404.2 1 2 0 0.0037 13 0 0 0 4.76E+06 5.87E+06 - - - 4.7408 0.9987 221125_WJC_METTL3_EV_vs_WT_F04.14072.14072.3 0.106 13/52 R.IEIVVVGTGDR[166.11]TER[166.11].L sp|Q9BU61|NDUF3_HUMAN 1 1562.8531 2.18 48099 14072 3 1562.851446 521.9583 NADH dehydrogenase [ubiquinone] 1 alpha subcomplex assembly factor 3 OS=Homo sapiens OX=9606 GN=NDUFAF3 PE=1 SV=1 4.68 2621.7 - 292405 - - - -1.0647 - 2.268 0.319 - 273.9 1 2 1 -0.0017 14 0 0 0 9.53E+06 4.38E+06 - - - 4.2723 0.9784 221125_WJC_METTL3_EV_vs_WT_F04.14074.14074.3 0.259 Dec-36 K.SSSVLLEHLR.S sp|Q9UEG4|ZN629_HUMAN 1 1139.6299 0.74 48101 14074 3 1139.628139 380.8839 Zinc finger protein 629 OS=Homo sapiens OX=9606 GN=ZNF629 PE=1 SV=2 6.47 2621.9 - 245842 - - - -1.5207 - 1.864 0.103 - 155.1 1 2 0 -0.0017 10 0 0 0 1.56E+06 2.11E+06 - - - 1.5065 0.9986 221125_WJC_METTL3_EV_vs_WT_F04.14076.14076.3 0.109 Oct-44 K.GGFLPPEEIK[136.11]ER[166.11].F sp|Q9H0D6|XRN2_HUMAN 1 1388.7419 1.02 48102 14076 3 1388.741192 463.9212 5'-3' exoribonuclease 2 OS=Homo sapiens OX=9606 GN=XRN2 PE=1 SV=1 4.79 2622.2 - 1.88E+06 - - - -0.499 - 1.985 0.337 - 86.2 1 2 1 -0.0007 12 0 0 0 4.99E+07 4.90E+07 - - - 4.1975 0.9993 221125_WJC_METTL3_EV_vs_WT_F04.14077.14077.2 0.11 18-Sep R.DETEFYLGK[136.11]R[166.11].C "sp|P18077|RL35A_HUMAN,tr|F8WB72|F8WB72_HUMAN,tr|C9K025|C9K025_HUMAN,tr|F8WBS5|F8WBS5_HUMAN" 4 1274.6262 0.58 48103 14077 2 1274.626005 638.3204 60S ribosomal protein L35a OS=Homo sapiens OX=9606 GN=RPL35A PE=1 SV=2 4.68 2622.4 - 345621 - - - -0.1428 - 1.792 0.265 - 322.8 1 2 0 -0.0002 10 0 0 0 1.16E+06 1.99E+06 - - - 2.6265 0.9999 221125_WJC_METTL3_EV_vs_WT_F04.14078.14078.2 1.15E-05 18-Dec K.NGQDLGVAFK.L "sp|Q00839|HNRPU_HUMAN,tr|A0A1W2PQL0|A0A1W2PQL0_HUMAN,tr|A0A1W2PPL4|A0A1W2PPL4_HUMAN,tr|A0A1W2PQ74|A0A1W2PQ74_HUMAN,tr|Q5RI18|Q5RI18_HUMAN,tr|A0A1W2PP35|A0A1W2PP35_HUMAN,tr|A0A1W2PPS1|A0A1W2PPS1_HUMAN,tr|A0A1W2PRZ7|A0A1W2PRZ7_HUMAN,tr|A0A1W2PPH7|A0A1W2PPH7_HUMAN,tr|A0A1W2PP34|A0A1W2PP34_HUMAN,tr|A0A1X7SBS1|A0A1X7SBS1_HUMAN" 11 1047.5349 0.96 48104 14078 2 1047.53499 524.7747 Heterogeneous nuclear ribonucleoprotein U OS=Homo sapiens OX=9606 GN=HNRNPU PE=1 SV=6 5.84 2622.4 - 8.76E+06 - - - 0.0773 - 2.257 0.525 - 746.4 1 2 0 0.0001 10 0 0 0 1.04E+08 1.08E+08 - - - 5.1908 0.9999 221125_WJC_METTL3_EV_vs_WT_F04.14080.14080.3 1.39E-05 14/40 K.LFNLSK[136.11]EDDVR[166.11].Q "sp|P62753|RS6_HUMAN,tr|A2A3R5|A2A3R5_HUMAN" 2 1352.7055 1.06 48106 14080 3 1352.705469 451.9091 40S ribosomal protein S6 OS=Homo sapiens OX=9606 GN=RPS6 PE=1 SV=1 4.56 2622.5 - 2.67E+06 - - - -0.0229 - 2.941 0.533 - 280.9 1 2 1 0 11 0 0 0 2.72E+07 2.56E+07 - - - 7.547 0.9999 221125_WJC_METTL3_EV_vs_WT_F04.14082.14082.2 0.00132 20-Dec K.EQISDIDDAVR[166.11].K sp|P53999|TCP4_HUMAN 1 1269.6076 0.39 48108 14082 2 1269.607447 635.8111 Activated RNA polymerase II transcriptional coactivator p15 OS=Homo sapiens OX=9606 GN=SUB1 PE=1 SV=3 3.84 2622.7 - 1.32E+06 - - - -0.1441 - 2.274 0.446 - 714.5 1 2 0 -0.0002 11 0 0 0 5.27E+07 1.34E+08 - - - 4.5576 0.9994 221125_WJC_METTL3_EV_vs_WT_F04.14083.14083.3 0.000456 Dec-52 R.IEIVVVGTGDRTER.L sp|Q9BU61|NDUF3_HUMAN 1 1542.8366 2.27 48109 14083 3 1542.835786 515.2861 NADH dehydrogenase [ubiquinone] 1 alpha subcomplex assembly factor 3 OS=Homo sapiens OX=9606 GN=NDUFAF3 PE=1 SV=1 4.68 2622.8 - 854290 - - - -0.5082 - 2.406 0.37 - 205.4 1 2 1 -0.0008 14 0 0 0 9.95E+06 4.38E+06 - - - 4.9981 0.9999 221125_WJC_METTL3_EV_vs_WT_F04.14085.14085.3 0.000675 Dec-64 R.GLIPAGTQHSMIATTGK[136.11].M "sp|Q9Y520|PRC2C_HUMAN,tr|E7EPN9|E7EPN9_HUMAN,tr|A0A2R8Y424|A0A2R8Y424_HUMAN,tr|H7C5N8|H7C5N8_HUMAN,tr|A0A2R8Y7F4|A0A2R8Y7F4_HUMAN,tr|A0A2R8YET2|A0A2R8YET2_HUMAN" 6 1689.8963 2.18 48111 14085 3 1689.897719 564.3061 Protein PRRC2C OS=Homo sapiens OX=9606 GN=PRRC2C PE=1 SV=4 8.76 2623.1 - 564827 - - - 0.816 - 2.379 0.381 - 191 1 2 0 0.0014 17 0 0 0 1.25E+07 5.73E+06 - - - 4.9769 0.9999 221125_WJC_METTL3_EV_vs_WT_F04.14086.14086.2 0.000163 20-Oct K.EQISDIDDAVR.K sp|P53999|TCP4_HUMAN 1 1259.5994 0.38 48112 14086 2 1259.599327 630.807 Activated RNA polymerase II transcriptional coactivator p15 OS=Homo sapiens OX=9606 GN=SUB1 PE=1 SV=3 3.84 2623.2 - 429024 - - - -0.0262 - 2.06 0.482 - 431.9 1 2 0 0 11 0 0 0 5.27E+07 1.37E+08 - - - 4.5561 0.9999 221125_WJC_METTL3_EV_vs_WT_F04.14087.14087.2 0.00137 20-Dec K.SQGMALSLGDK[136.11].L sp|P53618|COPB_HUMAN 1 1113.558 0.52 48113 14087 2 1113.557724 557.7863 Coatomer subunit beta OS=Homo sapiens OX=9606 GN=COPB1 PE=1 SV=3 5.55 2623.3 - 324938 - - - -0.211 - 2.246 0.461 - 475.7 1 2 0 -0.0002 11 0 0 0 2.72E+06 5.19E+06 - - - 4.6348 0.9945 221125_WJC_METTL3_EV_vs_WT_F04.14089.14089.2 0.172 18-Jul K.ISQSELFDNK[136.11].S sp|Q15398|DLGP5_HUMAN 1 1187.5914 1.21 48115 14089 2 1187.590821 594.803 Disks large-associated protein 5 OS=Homo sapiens OX=9606 GN=DLGAP5 PE=1 SV=2 4.37 2623.6 - 217406 - - - -0.4606 - 1.141 0.222 - 100.6 1 2 0 -0.0005 10 0 0 0 2.70E+06 2.23E+06 - - - 1.0487 0.9999 221125_WJC_METTL3_EV_vs_WT_F04.14091.14091.3 8.37E-06 14/40 K.LFNLSKEDDVR.Q "sp|P62753|RS6_HUMAN,tr|A2A3R5|A2A3R5_HUMAN" 2 1334.683 1.09 48116 14091 3 1334.682233 445.9016 40S ribosomal protein S6 OS=Homo sapiens OX=9606 GN=RPS6 PE=1 SV=1 4.56 2623.8 - 2.41E+06 - - - -0.5971 - 2.672 0.474 - 295.6 1 2 1 -0.0008 11 0 0 0 2.81E+07 2.58E+07 - - - 6.6165 1 221125_WJC_METTL3_EV_vs_WT_F04.14093.14093.3 7.55E-07 Dec-44 K.LTIHGDLYYEGK[136.11].E "sp|Q13435|SF3B2_HUMAN,tr|E9PPJ0|E9PPJ0_HUMAN,tr|H0YEX5|H0YEX5_HUMAN" 3 1415.7176 3.16 48117 14093 3 1415.717607 472.9132 Splicing factor 3B subunit 2 OS=Homo sapiens OX=9606 GN=SF3B2 PE=1 SV=2 5.32 2624 - 2.56E+06 - - - -0.017 - 2.456 0.583 - 178 1 2 0 0 12 0 0 0 8.64E+07 2.73E+07 - - - 7.5305 0.9999 221125_WJC_METTL3_EV_vs_WT_F04.14095.14095.3 9.11E-05 13/40 R.R[166.11]TDVNPFLAPR[166.11].S "sp|Q15643|TRIPB_HUMAN,tr|H0YJ97|H0YJ97_HUMAN" 2 1304.7104 2.48 48119 14095 3 1304.710846 435.9107 Thyroid receptor-interacting protein 11 OS=Homo sapiens OX=9606 GN=TRIP11 PE=1 SV=3 9.6 2624.1 - 1.96E+06 - - - 0.3349 - 2.36 0.413 - 358.4 1 2 0 0.0004 11 0 0 0 1.10E+08 4.41E+07 - - - 5.5837 0.9998 221125_WJC_METTL3_EV_vs_WT_F04.14096.14096.2 0.000307 20-Oct R.SAYQEAMDISK.K sp|P31947|1433S_HUMAN 1 1241.5598 15.28 48120 14096 2 1241.560852 621.7872 14-3-3 protein sigma OS=Homo sapiens OX=9606 GN=SFN PE=1 SV=1 4.37 2624.2 - 883018 - - - 0.8449 - 1.833 0.467 - 228.9 1 2 0 0.001 11 0 0 0 7.83E+06 5.13E+05 - - - 4.1292 0.9998 221125_WJC_METTL3_EV_vs_WT_F04.14097.14097.3 0.000359 Dec-36 K.NFDVGHVPIR[166.11].L "sp|P50579|MAP2_HUMAN,tr|F8VQZ7|F8VQZ7_HUMAN,tr|F8VRR3|F8VRR3_HUMAN" 3 1162.6123 0.75 48121 14097 3 1162.60894 388.5447 Methionine aminopeptidase 2 OS=Homo sapiens OX=9606 GN=METAP2 PE=1 SV=1 6.74 2624.4 - 749657 - - - -2.8574 - 2.258 0.429 - 307.1 1 2 0 -0.0033 10 0 0 0 4.99E+06 6.67E+06 - - - 5.7006 0.9995 221125_WJC_METTL3_EV_vs_WT_F04.14098.14098.3 0.00269 Nov-36 K.NFDVGHVPIR.L "sp|P50579|MAP2_HUMAN,tr|F8VQZ7|F8VQZ7_HUMAN,tr|F8VRR3|F8VRR3_HUMAN" 3 1152.604 0.72 48122 14098 3 1152.603764 385.2086 Methionine aminopeptidase 2 OS=Homo sapiens OX=9606 GN=METAP2 PE=1 SV=1 6.74 2624.5 - 561931 - - - -0.1978 - 1.771 0.331 - 177.6 1 2 0 -0.0002 10 0 0 0 4.60E+06 6.35E+06 - - - 3.8994 0.9742 221125_WJC_METTL3_EV_vs_WT_F04.14110.14110.3 0.00114 Sep-40 R.IRDQAWDDVVR.K sp|O00566|MPP10_HUMAN 1 1371.6895 0.88 48132 14110 3 1371.681703 458.2371 U3 small nucleolar ribonucleoprotein protein MPP10 OS=Homo sapiens OX=9606 GN=MPHOSPH10 PE=1 SV=2 4.43 2625.9 - 1.22E+06 - - - -5.693 - 1.885 0.372 - 115.5 1 2 1 -0.0078 11 0 0 0 8.19E+06 9.30E+06 - - - 4.4861 1 221125_WJC_METTL3_EV_vs_WT_F04.14111.14111.2 2.90E-06 20-Dec R.EEAENTLQSFR.Q "sp|P08670|VIME_HUMAN,tr|B0YJC5|B0YJC5_HUMAN,tr|B0YJC4|B0YJC4_HUMAN" 3 1322.6103 1.95 48133 14111 2 1322.609447 662.3124 Vimentin OS=Homo sapiens OX=9606 GN=VIM PE=1 SV=4 4.25 2626 - 1.21E+06 - - - -0.6139 - 2.392 0.622 - 654 1 2 0 -0.0008 11 0 0 0 2.44E+09 1.25E+09 - - - 5.9942 0.9992 221125_WJC_METTL3_EV_vs_WT_F04.14113.14113.3 0.00171 13/44 K.LISSDGHEFIVK.R "sp|Q15369|ELOC_HUMAN,tr|R4GMY8|R4GMY8_HUMAN,tr|E5RHG8|E5RHG8_HUMAN" 3 1343.7085 1.23 48135 14113 3 1343.711438 448.9101 Elongin-C OS=Homo sapiens OX=9606 GN=ELOC PE=1 SV=1 5.32 2626.2 - 903102 - - - 2.1746 - 2.102 0.313 - 222.6 1 2 0 0.0029 12 0 0 0 9.38E+06 7.66E+06 - - - 4.088 0.9999 221125_WJC_METTL3_EV_vs_WT_F04.14114.14114.3 1.42E-05 15/36 K.NQVLVFVHSR.K "sp|O75643|U520_HUMAN,tr|A0A494C1A5|A0A494C1A5_HUMAN" 2 1197.6618 1.48 48136 14114 3 1197.661174 400.2279 U5 small nuclear ribonucleoprotein 200 kDa helicase OS=Homo sapiens OX=9606 GN=SNRNP200 PE=1 SV=2 9.76 2626.3 - 885793 - - - -0.5569 - 2.611 0.316 - 551 1 2 0 -0.0007 10 0 0 0 5.15E+07 3.47E+07 - - - 4.8657 0.9868 221125_WJC_METTL3_EV_vs_WT_F04.14115.14115.2 0.105 22-Oct K.ETPPPLVPPAAR.E sp|Q9BQA1|MEP50_HUMAN 1 1243.6925 3.8 48137 14115 2 1243.687896 622.8535 Methylosome protein 50 OS=Homo sapiens OX=9606 GN=WDR77 PE=1 SV=1 6.1 2626.5 - 874927 - - - -3.6794 - 1.565 0.224 - 251 1 2 0 -0.0046 12 0 0 0 9.07E+06 2.39E+06 - - - 1.8725 0.9998 221125_WJC_METTL3_EV_vs_WT_F04.14116.14116.2 3.73E-07 15/20 R.RTDVNPFLAPR.S "sp|Q15643|TRIPB_HUMAN,tr|H0YJ97|H0YJ97_HUMAN" 2 1284.6939 1.3 48138 14116 2 1284.694207 643.3542 Thyroid receptor-interacting protein 11 OS=Homo sapiens OX=9606 GN=TRIP11 PE=1 SV=3 9.6 2626.6 - 808986 - - - 0.2631 - 2.913 0.303 - 372.8 1 2 0 0.0003 11 0 0 0 1.12E+07 8.62E+06 - - - 4.1712 0.9997 221125_WJC_METTL3_EV_vs_WT_F04.14117.14117.2 0.011 14/18 K.R[166.11]DELTLEGIK[136.11].Q "sp|P38919|IF4A3_HUMAN,tr|I3L3H2|I3L3H2_HUMAN" 2 1190.6626 2.02 48139 14117 2 1190.663301 596.3386 Eukaryotic initiation factor 4A-III OS=Homo sapiens OX=9606 GN=EIF4A3 PE=1 SV=4 4.68 2626.7 - 580408 - - - 0.6123 - 2.345 0.318 - 634.4 1 2 0 0.0007 10 0 0 0 2.78E+07 1.37E+07 - - - 3.7685 0.9998 221125_WJC_METTL3_EV_vs_WT_F04.14118.14118.3 0.00102 16/56 R.MVDVVEKEDVNEAIR.L sp|P33993|MCM7_HUMAN 1 1744.8665 0.76 48140 14118 3 1744.868419 582.6295 DNA replication licensing factor MCM7 OS=Homo sapiens OX=9606 GN=MCM7 PE=1 SV=4 4.18 2626.9 - 549709 - - - 1.0711 - 2.924 0.442 - 292.5 1 2 1 0.0019 15 0 0 0 9.47E+06 1.25E+07 - - - 6.2671 0.9904 221125_WJC_METTL3_EV_vs_WT_F04.14119.14119.2 4.74E-07 22-Oct K.LHEEEIQELQAQ.L "sp|P08670|VIME_HUMAN,tr|B0YJC5|B0YJC5_HUMAN,tr|B0YJC4|B0YJC4_HUMAN" 3 1465.7049 - 48141 14119 2 1465.703597 733.8597 Vimentin OS=Homo sapiens OX=9606 GN=VIM PE=1 SV=4 4.09 2627 - 513633 - - - -0.8808 - 2.475 0.429 - 393.1 1 1 0 -0.0013 12 0 0 0 - - - - - 4.5937 0.9945 221125_WJC_METTL3_EV_vs_WT_F04.14120.14120.2 0.00159 26-Jul K.ETLSPPGNGC[160.03]AIYR.S "sp|Q6W2J9|BCOR_HUMAN,tr|H7BZ37|H7BZ37_HUMAN,tr|H7C2V9|H7C2V9_HUMAN,tr|H7BYY2|H7BYY2_HUMAN,tr|H7C231|H7C231_HUMAN" 5 1533.7246 6.99 48142 14120 2 1533.72993 767.8696 BCL-6 corepressor OS=Homo sapiens OX=9606 GN=BCOR PE=1 SV=1 6.09 2627.1 - 475474 - - - 3.4902 - 1.335 0.374 - 75.8 1 2 0 0.0054 14 0 0 0 1.51E+07 2.16E+06 - - - 2.5267 0.98 221125_WJC_METTL3_EV_vs_WT_F04.14126.14126.2 0.000273 24-Nov K.AGNLGGGVVTIER[166.11].S "sp|P35268|RL22_HUMAN,tr|K7EKS7|K7EKS7_HUMAN,tr|K7ERI7|K7ERI7_HUMAN,tr|K7EMH1|K7EMH1_HUMAN,tr|K7ELC4|K7ELC4_HUMAN,tr|K7EP65|K7EP65_HUMAN,tr|K7EJT5|K7EJT5_HUMAN" 7 1251.6811 0.93 48148 14126 2 1251.690431 626.8478 60S ribosomal protein L22 OS=Homo sapiens OX=9606 GN=RPL22 PE=1 SV=2 6.05 2627.9 - 241415 - - - 7.4787 - 2.175 0.386 - 380.1 1 2 0 0.0094 13 0 0 0 3.31E+07 3.56E+07 - - - 3.8833 1 221125_WJC_METTL3_EV_vs_WT_F04.14130.14130.3 2.70E-07 16/36 K.NQVLVFVHSR[166.11].K "sp|O75643|U520_HUMAN,tr|A0A494C1A5|A0A494C1A5_HUMAN" 2 1207.6701 1.6 48150 14130 3 1207.669507 403.564 U5 small nuclear ribonucleoprotein 200 kDa helicase OS=Homo sapiens OX=9606 GN=SNRNP200 PE=1 SV=2 9.76 2628.4 - 1.45E+06 - - - -0.5001 - 2.78 0.544 - 673.3 1 2 0 -0.0006 10 0 0 0 5.29E+07 3.30E+07 - - - 7.5909 0.9997 221125_WJC_METTL3_EV_vs_WT_F04.14131.14131.2 0.00567 20-Sep K.EALPDGVNISK[136.11].E sp|Q9NRF9|DPOE3_HUMAN 1 1149.6121 1.16 48151 14131 2 1149.612204 575.8133 DNA polymerase epsilon subunit 3 OS=Homo sapiens OX=9606 GN=POLE3 PE=1 SV=1 4.37 2628.5 - 1.32E+06 - - - 0.0879 - 1.605 0.424 - 255.4 1 2 0 0.0001 11 0 0 0 1.93E+07 1.66E+07 - - - 3.4525 0.9987 221125_WJC_METTL3_EV_vs_WT_F04.14132.14132.3 0.000667 Nov-44 K.GGFLPPEEIKER.F sp|Q9H0D6|XRN2_HUMAN 1 1370.7194 1 48152 14132 3 1370.719094 457.9137 5'-3' exoribonuclease 2 OS=Homo sapiens OX=9606 GN=XRN2 PE=1 SV=1 4.79 2628.6 - 1.26E+06 - - - -0.2342 - 1.825 0.365 - 158.6 1 2 1 -0.0003 12 0 0 0 4.99E+07 4.99E+07 - - - 4.2768 1 221125_WJC_METTL3_EV_vs_WT_F04.14134.14134.2 1.55E-07 13/22 K.ITNDFYPEEDGK[136.11].T "sp|P55884|EIF3B_HUMAN,tr|C9JZG1|C9JZG1_HUMAN" 2 1434.6394 1.17 48154 14134 2 1434.641656 718.327 Eukaryotic translation initiation factor 3 subunit B OS=Homo sapiens OX=9606 GN=EIF3B PE=1 SV=3 3.92 2628.8 - 967612 - - - 1.5446 - 2.636 0.62 - 515.4 1 2 0 0.0022 12 0 0 0 1.91E+07 1.63E+07 - - - 6.1699 0.9992 221125_WJC_METTL3_EV_vs_WT_F04.14136.14136.2 0.00281 20-Aug K.K[136.11]ITIADC[160.03]GQLE.- sp|P62937|PPIA_HUMAN 1 1254.6369 0.98 48156 14136 2 1254.634466 628.3257 Peptidyl-prolyl cis-trans isomerase A OS=Homo sapiens OX=9606 GN=PPIA PE=1 SV=2 4.75 2629 - 934579 - - - -1.9703 - 1.732 0.384 - 248.7 1 2 0 -0.0025 11 0 0 0 8.27E+07 8.46E+07 - - - 3.3624 0.9998 221125_WJC_METTL3_EV_vs_WT_F04.14137.14137.2 2.75E-06 20-Sep R.DVPAYSQDTFK[136.11].V "sp|P04843|RPN1_HUMAN,tr|B7Z4L4|B7Z4L4_HUMAN" 2 1277.6019 0.07 48157 14137 2 1277.603437 639.8082 Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit 1 OS=Homo sapiens OX=9606 GN=RPN1 PE=1 SV=1 4.21 2629.1 - 784597 - - - 1.1772 - 1.878 0.517 - 231.6 1 2 0 0.0015 11 0 0 0 7.67E+05 1.18E+07 - - - 4.5639 0.9994 221125_WJC_METTL3_EV_vs_WT_F04.14139.14139.3 0.00437 16/40 K.EIFMQVEDERR.H sp|P35580|MYH10_HUMAN 1 1450.6875 0.96 48159 14139 3 1450.689586 484.5698 Myosin-10 OS=Homo sapiens OX=9606 GN=MYH10 PE=1 SV=3 4.41 2629.4 - 706803 - - - 1.4634 - 2.175 0.288 - 364.3 1 2 0 0.0021 11 0 0 0 1.08E+07 1.13E+07 - - - 3.9577 0.9999 221125_WJC_METTL3_EV_vs_WT_F04.14142.14142.2 2.82E-05 18-Nov K.NQVLVFVHSR.K "sp|O75643|U520_HUMAN,tr|A0A494C1A5|A0A494C1A5_HUMAN" 2 1197.6618 0.31 48162 14142 2 1197.661661 599.8382 U5 small nuclear ribonucleoprotein 200 kDa helicase OS=Homo sapiens OX=9606 GN=SNRNP200 PE=1 SV=2 9.76 2629.8 - 391455 - - - -0.1503 - 2.358 0.489 - 600.7 1 2 0 -0.0002 10 0 0 0 1.11E+07 3.64E+07 - - - 5.0471 0.9993 221125_WJC_METTL3_EV_vs_WT_F04.14148.14148.2 0.0027 13/18 K.RDELTLEGIK.Q "sp|P38919|IF4A3_HUMAN,tr|I3L3H2|I3L3H2_HUMAN" 2 1172.6401 2.01 48166 14148 2 1172.639558 587.3273 Eukaryotic initiation factor 4A-III OS=Homo sapiens OX=9606 GN=EIF4A3 PE=1 SV=4 4.68 2630.6 - 2.58E+06 - - - -0.4639 - 2.395 0.171 - 609.7 1 2 0 -0.0005 10 0 0 0 2.80E+07 1.39E+07 - - - 2.7417 0.9999 221125_WJC_METTL3_EV_vs_WT_F04.14149.14149.2 2.61E-05 14/20 R.QLVEQVEQIQK.E sp|Q9BVK6|TMED9_HUMAN 1 1340.73 1.41 48167 14149 2 1340.729327 671.3723 Transmembrane emp24 domain-containing protein 9 OS=Homo sapiens OX=9606 GN=TMED9 PE=1 SV=2 4.53 2630.6 - 4.10E+06 - - - -0.487 - 2.947 0.484 - 881.7 1 2 0 -0.0007 11 0 0 0 1.03E+08 7.30E+07 - - - 5.5394 0.9999 221125_WJC_METTL3_EV_vs_WT_F04.14151.14151.2 9.88E-05 20-Nov K.KITIADC[160.03]GQLE.- sp|P62937|PPIA_HUMAN 1 1246.6227 0.97 48169 14151 2 1246.623318 624.3186 Peptidyl-prolyl cis-trans isomerase A OS=Homo sapiens OX=9606 GN=PPIA PE=1 SV=2 4.75 2630.7 - 2.89E+06 - - - 0.4653 - 2.344 0.486 - 548.2 1 2 0 0.0006 11 0 0 0 8.53E+07 8.79E+07 - - - 4.9349 0.9999 221125_WJC_METTL3_EV_vs_WT_F04.14152.14152.3 7.19E-05 Nov-40 R.ISDFHETYTFK.Q "sp|Q6W2J9|BCOR_HUMAN,tr|H7BZ37|H7BZ37_HUMAN,tr|A1A564|A1A564_HUMAN,tr|H7C2V9|H7C2V9_HUMAN,tr|H7BYY2|H7BYY2_HUMAN,tr|H7C231|H7C231_HUMAN" 6 1386.6456 1.39 48170 14152 3 1386.645026 463.2225 BCL-6 corepressor OS=Homo sapiens OX=9606 GN=BCOR PE=1 SV=1 5.32 2630.8 - 2.88E+06 - - - -0.401 - 2.099 0.385 - 134.3 1 2 0 -0.0006 11 0 0 0 5.30E+07 3.81E+07 - - - 4.9386 0.9998 221125_WJC_METTL3_EV_vs_WT_F04.14153.14153.2 0.0102 13/20 R.QLVEQVEQIQK[136.11].E sp|Q9BVK6|TMED9_HUMAN 1 1348.7442 1.41 48171 14153 2 1348.744072 675.3794 Transmembrane emp24 domain-containing protein 9 OS=Homo sapiens OX=9606 GN=TMED9 PE=1 SV=2 4.53 2630.9 - 2.82E+06 - - - -0.0801 - 2.671 0.356 - 619.2 1 2 0 -0.0001 11 0 0 0 1.03E+08 7.30E+07 - - - 4.3281 1 221125_WJC_METTL3_EV_vs_WT_F04.14154.14154.3 1.77E-05 Dec-40 R.ISDFHETYTFK[136.11].Q "sp|Q6W2J9|BCOR_HUMAN,tr|H7BZ37|H7BZ37_HUMAN,tr|A1A564|A1A564_HUMAN,tr|H7C2V9|H7C2V9_HUMAN,tr|H7BYY2|H7BYY2_HUMAN,tr|H7C231|H7C231_HUMAN" 6 1394.6598 1.39 48172 14154 3 1394.659359 465.8939 BCL-6 corepressor OS=Homo sapiens OX=9606 GN=BCOR PE=1 SV=1 5.32 2630.9 - 2.22E+06 - - - -0.3033 - 2.389 0.448 - 193.1 1 2 0 -0.0004 11 0 0 0 5.30E+07 3.81E+07 - - - 6.0086 0.9998 221125_WJC_METTL3_EV_vs_WT_F04.14155.14155.3 0.00264 13/40 R.EEAENTLQSFR.Q "sp|P08670|VIME_HUMAN,tr|B0YJC5|B0YJC5_HUMAN,tr|B0YJC4|B0YJC4_HUMAN" 3 1322.6103 2.12 48173 14155 3 1322.610759 441.8774 Vimentin OS=Homo sapiens OX=9606 GN=VIM PE=1 SV=4 4.25 2631 - 1.45E+06 - - - 0.378 - 1.967 0.367 - 238.1 1 2 0 0.0005 11 0 0 0 5.44E+07 2.57E+07 - - - 4.5534 0.9998 221125_WJC_METTL3_EV_vs_WT_F04.14156.14156.3 0.00246 13/40 K.EIFMQVEDER[166.11]R[166.11].H sp|P35580|MYH10_HUMAN 1 1470.704 0.95 48174 14156 3 1470.704282 491.2419 Myosin-10 OS=Homo sapiens OX=9606 GN=MYH10 PE=1 SV=3 4.41 2631.1 - 1.35E+06 - - - 0.1897 - 1.998 0.362 - 209.5 1 2 0 0.0003 11 0 0 0 1.09E+07 1.15E+07 - - - 4.5421 0.9871 221125_WJC_METTL3_EV_vs_WT_F04.14158.14158.3 0.139 Nov-40 R.EEAENTLQSFR[166.11].Q "sp|P08670|VIME_HUMAN,tr|B0YJC5|B0YJC5_HUMAN,tr|B0YJC4|B0YJC4_HUMAN" 3 1332.6185 2.1 48176 14158 3 1332.619318 445.2135 Vimentin OS=Homo sapiens OX=9606 GN=VIM PE=1 SV=4 4.25 2631.3 - 809429 - - - 0.5921 - 1.322 0.208 - 152.4 1 2 0 0.0008 11 0 0 0 5.44E+07 2.59E+07 - - - 1.6518 0.9994 221125_WJC_METTL3_EV_vs_WT_F04.14159.14159.2 0.00685 18-Aug K.STLTDSLVC[160.03]K[136.11].A sp|P13639|EF2_HUMAN 1 1130.5733 0.4 48177 14159 2 1130.574154 566.2939 Elongation factor 2 OS=Homo sapiens OX=9606 GN=EEF2 PE=1 SV=4 5.55 2631.5 - 705062 - - - 0.7775 - 1.806 0.316 - 205.9 1 2 0 0.0009 10 0 0 0 3.56E+06 8.97E+06 - - - 3.0247 1 221125_WJC_METTL3_EV_vs_WT_F04.14160.14160.2 3.69E-08 13/22 K.SGGATIEELTEK.C "sp|P18583|SON_HUMAN,tr|H7C1M2|H7C1M2_HUMAN,tr|H7C2G8|H7C2G8_HUMAN,tr|J3QSZ5|J3QSZ5_HUMAN" 4 1233.6089 2.95 48178 14160 2 1233.60532 617.8117 Protein SON OS=Homo sapiens OX=9606 GN=SON PE=1 SV=4 4.25 2631.6 - 509570 - - - -2.8713 - 2.961 0.582 - 656.7 1 2 0 -0.0035 12 0 0 0 3.57E+07 1.21E+07 - - - 6.1947 0.9902 221125_WJC_METTL3_EV_vs_WT_F04.14162.14162.2 0.0592 18-Aug K.STLTDSLVC[160.03]K.A sp|P13639|EF2_HUMAN 1 1122.5591 0.37 48180 14162 2 1122.55542 562.2868 Elongation factor 2 OS=Homo sapiens OX=9606 GN=EEF2 PE=1 SV=4 5.55 2631.9 - 251790 - - - -3.256 - 1.541 0.219 - 160 1 2 0 -0.0037 10 0 0 0 3.56E+06 9.52E+06 - - - 1.8644 1 221125_WJC_METTL3_EV_vs_WT_F04.14168.14168.2 0.000398 15/20 K.TRLEQEIATYR.R "sp|Q04695|K1C17_HUMAN,sp|P02533|K1C14_HUMAN,sp|P35900|K1C20_HUMAN,sp|P08779|K1C16_HUMAN,sp|P19012|K1C15_HUMAN,sp|P13646|K1C13_HUMAN,tr|A0A3B3IS58|A0A3B3IS58_HUMAN,tr|F5GWP8|F5GWP8_HUMAN,tr|K7ERE3|K7ERE3_HUMAN,tr|A8MT21|A8MT21_HUMAN" 10 1378.7205 3591.16 48185 14168 2 1378.721489 690.3675 "Keratin, type I cytoskeletal 17 OS=Homo sapiens OX=9606 GN=KRT17 PE=1 SV=2" 5.81 2632.6 - 1.26E+06 - - - 0.7333 - 3.145 0.556 - 289.4 1 2 1 0.001 11 0 0 0 5.30E+08 1.48E+05 - - - 6.247 0.9832 221125_WJC_METTL3_EV_vs_WT_F04.14169.14169.2 2.26E-05 24-Sep K.EASGDLPEAQIVK[136.11].H "sp|P52948|NUP98_HUMAN,tr|A0A3B3ITD8|A0A3B3ITD8_HUMAN,tr|H7C3P6|H7C3P6_HUMAN" 3 1363.7075 2 48186 14169 2 1363.697836 682.861 Nuclear pore complex protein Nup98-Nup96 OS=Homo sapiens OX=9606 GN=NUP98 PE=1 SV=4 4.14 2632.7 - 462378 - - - -7.0572 - 1.801 0.464 - 210 1 2 0 -0.0096 13 0 0 0 1.99E+07 9.95E+06 - - - 3.9751 0.9996 221125_WJC_METTL3_EV_vs_WT_F04.14170.14170.2 0.0011 22-Oct R.GEPPLPEEDLSK.L "sp|O15372|EIF3H_HUMAN,tr|B3KS98|B3KS98_HUMAN,tr|A0A087WZK9|A0A087WZK9_HUMAN" 3 1309.6402 2.21 48187 14170 2 1309.640281 655.8274 Eukaryotic translation initiation factor 3 subunit H OS=Homo sapiens OX=9606 GN=EIF3H PE=1 SV=1 4 2632.8 - 2.54E+06 - - - 0.0909 - 1.775 0.384 - 211.2 1 2 0 0.0001 12 0 0 0 3.05E+07 1.38E+07 - - - 3.387 0.9999 221125_WJC_METTL3_EV_vs_WT_F04.14172.14172.3 1.65E-05 14/48 R.EQGVEEHETLLLR[166.11].R sp|Q9Y490|TLN1_HUMAN 1 1561.7976 1.11 48189 14172 3 1561.794586 521.6065 Talin-1 OS=Homo sapiens OX=9606 GN=TLN1 PE=1 SV=3 4.48 2633 - 771577 - - - -1.9017 - 2.47 0.431 - 297.4 1 2 0 -0.003 13 0 0 0 1.60E+07 1.44E+07 - - - 5.796 0.9998 221125_WJC_METTL3_EV_vs_WT_F04.14173.14173.2 0.000128 22-Nov R.TIEYLQPNPASR[166.11].A "sp|Q99961|SH3G1_HUMAN,sp|Q99962|SH3G2_HUMAN,tr|M0R0I3|M0R0I3_HUMAN,tr|M0QYE0|M0QYE0_HUMAN" 4 1397.7178 1.21 48190 14173 2 1397.720045 699.8662 Endophilin-A2 OS=Homo sapiens OX=9606 GN=SH3GL1 PE=1 SV=1 5.66 2633.1 - 629974 - - - 1.5711 - 2.3 0.476 - 399.5 1 2 0 0.0022 12 0 0 0 2.80E+07 2.31E+07 - - - 4.7476 0.9998 221125_WJC_METTL3_EV_vs_WT_F04.14174.14174.2 5.98E-05 24-Nov K.EASGDLPEAQIVK[136.11].H "sp|P52948|NUP98_HUMAN,tr|A0A3B3ITD8|A0A3B3ITD8_HUMAN,tr|H7C3P6|H7C3P6_HUMAN" 3 1363.7075 2 48191 14174 2 1363.706468 682.861 Nuclear pore complex protein Nup98-Nup96 OS=Homo sapiens OX=9606 GN=NUP98 PE=1 SV=4 4.14 2633.3 - 462378 - - - -0.7274 - 1.99 0.429 - 318.6 1 2 0 -0.001 13 0 0 0 1.99E+07 9.95E+06 - - - 3.9754 0.9998 221125_WJC_METTL3_EV_vs_WT_F04.14176.14176.3 0.000824 Oct-40 K.FTVVAISPPRK.N sp|Q10469|MGAT2_HUMAN 1 1213.7183 1.14 48193 14176 3 1213.718747 405.58 "Alpha-1,6-mannosyl-glycoprotein 2-beta-N-acetylglucosaminyltransferase OS=Homo sapiens OX=9606 GN=MGAT2 PE=1 SV=1" 11 2633.5 - 248104 - - - 0.3741 - 2.13 0.358 - 99.6 1 2 0 0.0005 11 0 0 0 4.92E+06 4.32E+06 - - - 4.6792 0.8503 221125_WJC_METTL3_EV_vs_WT_F04.14178.14178.2 0.057 26-Jul R.TQSSASLAASYAAQ.Q sp|Q96PK6|RBM14_HUMAN 1 1354.6365 - 48194 14178 2 1354.635298 678.3255 RNA-binding protein 14 OS=Homo sapiens OX=9606 GN=RBM14 PE=1 SV=2 5.18 2633.7 - 2.45E+06 - - - -0.8681 - 1.172 0.292 - 104.4 1 1 0 -0.0012 14 0 0 0 - - - - - 1.5956 0.9999 221125_WJC_METTL3_EV_vs_WT_F04.14180.14180.2 2.77E-07 18-Dec K.C[160.03]PFTGNVSIR[166.11].G "sp|P62280|RS11_HUMAN,tr|M0QZC5|M0QZC5_HUMAN" 2 1159.5683 0.98 48196 14180 2 1159.567669 580.7915 40S ribosomal protein S11 OS=Homo sapiens OX=9606 GN=RPS11 PE=1 SV=3 8.25 2634 - 1.53E+06 - - - -0.5856 - 2.101 0.549 - 745.1 1 2 0 -0.0007 10 0 0 0 1.12E+07 1.14E+07 - - - 5.168 0.9999 221125_WJC_METTL3_EV_vs_WT_F04.14181.14181.3 5.24E-05 Dec-48 R.EQGVEEHETLLLR.R sp|Q9Y490|TLN1_HUMAN 1 1551.7893 1.02 48197 14181 3 1551.790846 518.2704 Talin-1 OS=Homo sapiens OX=9606 GN=TLN1 PE=1 SV=3 4.48 2634.1 - 994576 - - - 1.0053 - 2.44 0.375 - 251.8 1 2 0 0.0016 13 0 0 0 1.66E+07 1.62E+07 - - - 5.1389 1 221125_WJC_METTL3_EV_vs_WT_F04.14182.14182.3 1.18E-07 14/48 R.IIGHFFASQTAQR[166.11].K "sp|Q9Y6M1|IF2B2_HUMAN,tr|F8W930|F8W930_HUMAN" 2 1484.7764 1.47 48198 14182 3 1484.775101 495.9327 Insulin-like growth factor 2 mRNA-binding protein 2 OS=Homo sapiens OX=9606 GN=IGF2BP2 PE=1 SV=2 9.76 2634.2 - 824113 - - - -0.8527 - 2.63 0.45 - 253.5 1 2 0 -0.0013 13 0 0 0 3.60E+07 2.44E+07 - - - 6.1785 1 221125_WJC_METTL3_EV_vs_WT_F04.14183.14183.2 0.000954 22-Dec K.TEELEEESFPER.S "sp|Q9Y2W1|TR150_HUMAN,tr|A0A3B3ITZ9|A0A3B3ITZ9_HUMAN" 2 1493.6522 2.83 48199 14183 2 1493.649542 747.8334 Thyroid hormone receptor-associated protein 3 OS=Homo sapiens OX=9606 GN=THRAP3 PE=1 SV=2 3.9 2634.3 - 691084 - - - -1.7681 - 2.699 0.598 - 591.9 1 2 0 -0.0026 12 0 0 0 2.80E+09 9.87E+08 - - - 6.0694 0.9999 221125_WJC_METTL3_EV_vs_WT_F04.14188.14188.2 5.04E-05 24-Dec K.AGGVGLNLSAASR[166.11].V "sp|Q14527|HLTF_HUMAN,tr|H7C5K0|H7C5K0_HUMAN,tr|A0A0C4DGA6|A0A0C4DGA6_HUMAN" 3 1181.6392 5.35 48204 14188 2 1181.639234 591.8269 Helicase-like transcription factor OS=Homo sapiens OX=9606 GN=HLTF PE=1 SV=2 9.79 2635 - 313248 - - - 0.0245 - 2.184 0.471 - 502.9 1 2 0 0 13 0 0 0 1.78E+07 3.33E+06 - - - 4.5247 0.9961 221125_WJC_METTL3_EV_vs_WT_F04.14189.14189.2 0.036 22-Jun K.NAGVEGSLIVEK[136.11].L "sp|P10809|CH60_HUMAN,tr|A0A7I2V2X6|A0A7I2V2X6_HUMAN,tr|A0A7I2YQK6|A0A7I2YQK6_HUMAN,tr|A0A7I2V599|A0A7I2V599_HUMAN" 4 1222.6649 0.97 48205 14189 2 1222.663666 612.3397 "60 kDa heat shock protein, mitochondrial OS=Homo sapiens OX=9606 GN=HSPD1 PE=1 SV=2" 4.53 2635.1 - 204576 - - - -0.9823 - 1.234 0.245 - 84.2 1 2 0 -0.0012 12 0 0 0 1.36E+06 1.40E+06 - - - 1.4034 0.9996 221125_WJC_METTL3_EV_vs_WT_F04.14193.14193.3 0.000661 Oct-44 R.TTAENEFVMLKK.D "sp|P13647|K2C5_HUMAN,tr|F8W0C6|F8W0C6_HUMAN,tr|H0YIN9|H0YIN9_HUMAN" 3 1409.7225 5.93 48207 14193 3 1409.7184 470.9148 "Keratin, type II cytoskeletal 5 OS=Homo sapiens OX=9606 GN=KRT5 PE=1 SV=3" 5.81 2635.5 - 3.74E+06 - - - -2.8743 - 1.858 0.428 - 147.7 1 2 0 -0.0041 12 0 0 0 2.51E+08 4.23E+07 - - - 5.0278 0.9087 221125_WJC_METTL3_EV_vs_WT_F04.14194.14194.3 0.365 Sep-40 R.QLVEQVEQIQK.E sp|Q9BVK6|TMED9_HUMAN 1 1340.73 2.27 48208 14194 3 1340.727487 447.9173 Transmembrane emp24 domain-containing protein 9 OS=Homo sapiens OX=9606 GN=TMED9 PE=1 SV=2 4.53 2635.7 - 1.12E+06 - - - -1.8594 - 1.782 0.053 - 127 1 2 0 -0.0025 11 0 0 0 1.03E+07 4.56E+06 - - - 0.7715 0.9985 221125_WJC_METTL3_EV_vs_WT_F04.14195.14195.3 5.29E-05 13/44 R.DLDELSR[166.11]YPEDK[136.11].L "sp|P43243|MATR3_HUMAN,tr|A8MXP9|A8MXP9_HUMAN,tr|D6R991|D6R991_HUMAN,tr|A0A0R4J2E8|A0A0R4J2E8_HUMAN,tr|D6REM6|D6REM6_HUMAN" 5 1496.7114 1.5 48209 14195 3 1496.709518 499.9111 Matrin-3 OS=Homo sapiens OX=9606 GN=MATR3 PE=1 SV=2 4.11 2635.8 - 1.01E+06 - - - -1.2394 - 1.957 0.345 - 165.4 1 2 1 -0.0019 12 0 0 0 2.24E+08 1.49E+08 - - - 4.247 1 221125_WJC_METTL3_EV_vs_WT_F04.14196.14196.2 2.45E-07 22-Dec K.TEELEEESFPER[166.11].S "sp|Q9Y2W1|TR150_HUMAN,tr|A0A3B3ITZ9|A0A3B3ITZ9_HUMAN" 2 1503.6605 2.83 48210 14196 2 1503.659429 752.8375 Thyroid hormone receptor-associated protein 3 OS=Homo sapiens OX=9606 GN=THRAP3 PE=1 SV=2 3.9 2635.9 - 694515 - - - -0.681 - 2.364 0.627 - 231 1 2 0 -0.001 12 0 0 0 2.80E+09 9.87E+08 - - - 5.9354 0.9985 221125_WJC_METTL3_EV_vs_WT_F04.14198.14198.2 0.000133 22-Nov K.AFEEDIETPPTR.N sp|Q9P2D1|CHD7_HUMAN 1 1403.6569 1.69 48212 14198 2 1403.6507 702.8357 Chromodomain-helicase-DNA-binding protein 7 OS=Homo sapiens OX=9606 GN=CHD7 PE=1 SV=3 4 2636.2 - 382805 - - - -4.3992 - 2.208 0.509 - 423.6 1 2 0 -0.0062 12 0 0 0 1.33E+07 7.87E+06 - - - 4.8827 0.9656 221125_WJC_METTL3_EV_vs_WT_F04.14205.14205.2 6.72 12-Jun R.SIFDHIK.L "sp|Q9NYF8|BCLF1_HUMAN,tr|E9PKI6|E9PKI6_HUMAN,tr|A0A1W2PQ43|A0A1W2PQ43_HUMAN,tr|E9PK91|E9PK91_HUMAN,tr|E9PJA7|E9PJA7_HUMAN,tr|E9PK09|E9PK09_HUMAN,tr|E9PQN2|E9PQN2_HUMAN" 7 858.46 2.09 48217 14205 2 858.459148 430.2373 Bcl-2-associated transcription factor 1 OS=Homo sapiens OX=9606 GN=BCLAF1 PE=1 SV=2 6.46 2636.9 - 5.24E+06 - - - -0.9377 - 1.011 0.112 - 90.3 1 2 0 -0.0008 7 0 0 0 1.04E+08 4.98E+07 - - - -0.0974 0.9985 221125_WJC_METTL3_EV_vs_WT_F04.14206.14206.3 0.000568 Dec-44 R.DLDELSRYPEDK.L "sp|P43243|MATR3_HUMAN,tr|A8MXP9|A8MXP9_HUMAN,tr|D6R991|D6R991_HUMAN,tr|A0A0R4J2E8|A0A0R4J2E8_HUMAN,tr|D6REM6|D6REM6_HUMAN" 5 1478.6889 1.51 48218 14206 3 1478.688524 493.9036 Matrin-3 OS=Homo sapiens OX=9606 GN=MATR3 PE=1 SV=2 4.11 2637 - 1.42E+06 - - - -0.2563 - 2.303 0.298 - 111.8 1 2 1 -0.0004 12 0 0 0 2.25E+08 1.49E+08 - - - 4.1746 0.996 221125_WJC_METTL3_EV_vs_WT_F04.14209.14209.2 0.000905 22-Dec R.TTAENEFVMLKK.D "sp|P13647|K2C5_HUMAN,tr|F8W0C6|F8W0C6_HUMAN,tr|H0YIN9|H0YIN9_HUMAN" 3 1409.7225 5501.92 48221 14209 2 1409.723689 705.8685 "Keratin, type II cytoskeletal 5 OS=Homo sapiens OX=9606 GN=KRT5 PE=1 SV=3" 5.81 2637.4 - 625348 - - - 0.8775 - 2.158 0.049 - 450.6 1 2 0 0.0012 12 0 0 0 6.92E+08 1.26E+05 - - - 1.4264 0.9996 221125_WJC_METTL3_EV_vs_WT_F04.14212.14212.3 0.00712 Dec-36 K.RDELTLEGIK.Q "sp|P38919|IF4A3_HUMAN,tr|I3L3H2|I3L3H2_HUMAN" 2 1172.6401 1.36 48224 14212 3 1172.639066 391.8873 Eukaryotic initiation factor 4A-III OS=Homo sapiens OX=9606 GN=EIF4A3 PE=1 SV=4 4.68 2637.8 - 468795 - - - -0.8835 - 2.275 0.283 - 207.4 1 2 0 -0.001 10 0 0 0 1.85E+07 1.36E+07 - - - 4.0954 0.9643 221125_WJC_METTL3_EV_vs_WT_F04.14217.14217.2 3.49 12-Jun R.SIFDHIK[136.11].L "sp|Q9NYF8|BCLF1_HUMAN,tr|E9PKI6|E9PKI6_HUMAN,tr|A0A1W2PQ43|A0A1W2PQ43_HUMAN,tr|E9PK91|E9PK91_HUMAN,tr|E9PJA7|E9PJA7_HUMAN,tr|E9PK09|E9PK09_HUMAN,tr|E9PQN2|E9PQN2_HUMAN" 7 866.4742 2.1 48227 14217 2 866.474724 434.2444 Bcl-2-associated transcription factor 1 OS=Homo sapiens OX=9606 GN=BCLAF1 PE=1 SV=2 6.46 2638.4 - 4.28E+06 - - - 0.659 - 0.907 0.154 - 91.9 1 2 0 0.0006 7 0 0 0 1.05E+08 4.98E+07 - - - -0.131 1 221125_WJC_METTL3_EV_vs_WT_F04.14218.14218.3 2.76E-07 15/44 K.VNGR[166.11]PLEMIEPR[166.11].T "sp|P62249|RS16_HUMAN,tr|M0R3H0|M0R3H0_HUMAN,tr|M0R1M5|M0R1M5_HUMAN,tr|Q6IPX4|Q6IPX4_HUMAN" 4 1429.7615 0.59 48228 14218 3 1429.761053 477.5944 40S ribosomal protein S16 OS=Homo sapiens OX=9606 GN=RPS16 PE=1 SV=2 6.11 2638.5 - 4.90E+06 - - - -0.284 - 2.807 0.485 - 300.5 1 2 0 -0.0004 12 0 0 0 1.83E+08 3.13E+08 - - - 6.808 0.9996 221125_WJC_METTL3_EV_vs_WT_F04.14219.14219.3 0.00198 16/48 R.GR[166.11]APQVLVLAPTR[166.11].E sp|Q9NR30|DDX21_HUMAN 1 1396.8418 0.91 48229 14219 3 1396.841523 466.6212 Nucleolar RNA helicase 2 OS=Homo sapiens OX=9606 GN=DDX21 PE=1 SV=5 12 2638.5 - 1.78E+06 - - - -0.1682 - 2.956 0.357 - 438 1 2 1 -0.0002 13 0 0 0 2.27E+07 2.49E+07 - - - 5.4587 0.9999 221125_WJC_METTL3_EV_vs_WT_F04.14220.14220.2 7.55E-05 20-Nov K.ETTIDGEELVK.L "sp|P52732|KIF11_HUMAN,tr|A0A7I2YQY4|A0A7I2YQY4_HUMAN,tr|A0A7I2V3A9|A0A7I2V3A9_HUMAN,tr|A0A7I2V3V3|A0A7I2V3V3_HUMAN" 4 1232.6136 5.95 48230 14220 2 1232.613718 617.3141 Kinesin-like protein KIF11 OS=Homo sapiens OX=9606 GN=KIF11 PE=1 SV=2 4 2638.6 - 1.48E+06 - - - 0.0852 - 2.159 0.532 - 502.4 1 2 0 0.0001 11 0 0 0 5.29E+07 8.89E+06 - - - 5.0524 0.9998 221125_WJC_METTL3_EV_vs_WT_F04.14224.14224.2 0.000835 16-Oct K.QQQVDIPLR[166.11].L sp|Q9NZI8|IF2B1_HUMAN 1 1105.6119 1.42 48234 14224 2 1105.612961 553.8132 Insulin-like growth factor 2 mRNA-binding protein 1 OS=Homo sapiens OX=9606 GN=IGF2BP1 PE=1 SV=2 5.84 2639.2 - 457627 - - - 0.9352 - 1.923 0.452 - 592.8 1 2 0 0.001 9 0 0 0 1.04E+07 7.32E+06 - - - 4.2709 0.9999 221125_WJC_METTL3_EV_vs_WT_F04.14225.14225.2 1.79E-08 18-Dec K.HGDVITIIDR.S sp|P46013|KI67_HUMAN 1 1137.6142 1.97 48235 14225 2 1137.613898 569.8144 Proliferation marker protein Ki-67 OS=Homo sapiens OX=9606 GN=MKI67 PE=1 SV=2 5.21 2639.3 - 369046 - - - -0.2848 - 2.14 0.608 - 417.1 1 2 0 -0.0003 10 0 0 0 6.74E+06 3.42E+06 - - - 5.6552 1 221125_WJC_METTL3_EV_vs_WT_F04.14232.14232.2 0.00408 16/28 R.AGTGVDNVDLEAATR.K "sp|O43175|SERA_HUMAN,tr|A0A2C9F2M7|A0A2C9F2M7_HUMAN,tr|A0A286YFB2|A0A286YFB2_HUMAN,tr|A0A286YFC8|A0A286YFC8_HUMAN,tr|A0A286YF22|A0A286YF22_HUMAN,tr|A0A286YFL2|A0A286YFL2_HUMAN,tr|A0A286YFA2|A0A286YFA2_HUMAN,tr|A0A286YFM8|A0A286YFM8_HUMAN,tr|A0A286YER3|A0A286YER3_HUMAN" 9 1487.7216 1.11 48240 14232 2 1487.722404 744.8681 D-3-phosphoglycerate dehydrogenase OS=Homo sapiens OX=9606 GN=PHGDH PE=1 SV=4 4.03 2640.1 - 2.40E+06 - - - 0.5404 - 3.23 0.55 - 843 1 2 0 0.0008 15 0 0 0 1.67E+08 1.50E+08 - - - 5.9856 0.9637 221125_WJC_METTL3_EV_vs_WT_F04.14233.14233.2 0.00326 22-Nov K.TQVVAGTNYYIK.V "sp|P01040|CYTA_HUMAN,tr|C9J0E4|C9J0E4_HUMAN" 2 1355.7085 999 48241 14233 2 1355.700446 678.8615 Cystatin-A OS=Homo sapiens OX=9606 GN=CSTA PE=1 SV=1 8.17 2640.2 - 1.88E+06 - - - -5.9526 - 2.047 0.196 - 313.8 1 2 0 -0.0081 12 0 0 0 1.83E+07 0.00E+00 - - - 2.371 0.9998 221125_WJC_METTL3_EV_vs_WT_F04.14234.14234.3 1.37E-05 Nov-36 R.EFEVYGPIK[136.11]R[166.11].L "sp|P08621|RU17_HUMAN,tr|M0QYR1|M0QYR1_HUMAN" 2 1254.6727 1.24 48242 14234 3 1254.668718 419.2315 U1 small nuclear ribonucleoprotein 70 kDa OS=Homo sapiens OX=9606 GN=SNRNP70 PE=1 SV=2 6.24 2640.4 - 731035 - - - -3.208 - 2.008 0.476 - 230.2 1 2 0 -0.004 10 0 0 0 3.19E+07 2.58E+07 - - - 5.8818 0.9999 221125_WJC_METTL3_EV_vs_WT_F04.14236.14236.2 0.000852 13/24 R.AIEINPDSAQPYK.W "sp|P50502|F10A1_HUMAN,sp|Q8NFI4|F10A5_HUMAN,sp|Q8IZP2|ST134_HUMAN,tr|Q3KNR6|Q3KNR6_HUMAN,tr|H7C3I1|H7C3I1_HUMAN,tr|F6VDH7|F6VDH7_HUMAN" 6 1444.7198 1.53 48244 14236 2 1444.720164 723.3672 Hsc70-interacting protein OS=Homo sapiens OX=9606 GN=ST13 PE=1 SV=2 4.37 2640.6 - 627442 - - - 0.2457 - 2.471 0.445 - 525 1 2 0 0.0004 13 0 0 0 4.62E+07 3.02E+07 - - - 4.6494 0.9996 221125_WJC_METTL3_EV_vs_WT_F04.14238.14238.2 0.00325 22-Oct K.VNGR[166.11]PLEMIEPR[166.11].T "sp|P62249|RS16_HUMAN,tr|M0R3H0|M0R3H0_HUMAN,tr|M0R1M5|M0R1M5_HUMAN,tr|Q6IPX4|Q6IPX4_HUMAN" 4 1429.7615 0.01 48246 14238 2 1429.760659 715.888 40S ribosomal protein S16 OS=Homo sapiens OX=9606 GN=RPS16 PE=1 SV=2 6.11 2640.9 - 591691 - - - -0.5595 - 1.92 0.359 - 175 1 2 0 -0.0008 12 0 0 0 2.60E+05 2.43E+07 - - - 3.4087 0.9987 221125_WJC_METTL3_EV_vs_WT_F04.14240.14240.2 0.0459 24-Sep R.AIEINPDSAQPYK[136.11].W "sp|P50502|F10A1_HUMAN,sp|Q8NFI4|F10A5_HUMAN,sp|Q8IZP2|ST134_HUMAN,tr|Q3KNR6|Q3KNR6_HUMAN,tr|H7C3I1|H7C3I1_HUMAN,tr|F6VDH7|F6VDH7_HUMAN" 6 1452.734 1.52 48248 14240 2 1452.73626 727.3743 Hsc70-interacting protein OS=Homo sapiens OX=9606 GN=ST13 PE=1 SV=2 4.37 2641.1 - 557751 - - - 1.5495 - 2.017 0.248 - 250.3 1 2 0 0.0023 13 0 0 0 4.62E+07 3.04E+07 - - - 2.6727 0.9975 221125_WJC_METTL3_EV_vs_WT_F04.14241.14241.2 0.041 18-Jul K.NQDEQEIPFR[166.11].L "sp|Q6PK04|CC137_HUMAN,tr|I3L0U5|I3L0U5_HUMAN" 2 1284.5974 0.68 48249 14241 2 1284.597552 643.306 Coiled-coil domain-containing protein 137 OS=Homo sapiens OX=9606 GN=CCDC137 PE=1 SV=1 4.14 2641.3 - 247245 - - - 0.1191 - 1.029 0.338 - 129.1 1 2 0 0.0002 10 0 0 0 2.14E+06 3.16E+06 - - - 1.6172 0.9992 221125_WJC_METTL3_EV_vs_WT_F04.14242.14242.2 6.27E-05 24-Sep K.ETEYQALQETNMK.F "sp|Q15643|TRIPB_HUMAN,tr|H0YJ97|H0YJ97_HUMAN" 2 1583.7137 1.96 48250 14242 2 1583.719488 792.8641 Thyroid receptor-interacting protein 11 OS=Homo sapiens OX=9606 GN=TRIP11 PE=1 SV=3 4.25 2641.4 - 123513 - - - 3.6307 - 1.997 0.563 - 236.1 1 2 0 0.0057 13 0 0 0 9.92E+06 5.06E+06 - - - 4.9726 0.9995 221125_WJC_METTL3_EV_vs_WT_F04.14246.14246.2 0.000114 18-Oct K.YEELQITAGR.H "sp|P04264|K2C1_HUMAN,sp|P04259|K2C6B_HUMAN" 2 1178.5932 351.7 48252 14246 2 1178.594352 590.3039 "Keratin, type II cytoskeletal 1 OS=Homo sapiens OX=9606 GN=KRT1 PE=1 SV=6" 4.53 2642 - 3.08E+06 - - - 1.0182 - 2.171 0.302 - 411.9 1 2 0 0.0012 10 0 0 0 4.25E+08 1.21E+06 - - - 3.435 0.9998 221125_WJC_METTL3_EV_vs_WT_F04.14247.14247.3 0.000107 Oct-60 K.EILGTAQSVGC[160.03]NVDGR.H sp|P30050|RL12_HUMAN 1 1674.7995 1.43 48253 14247 3 1674.800475 559.2738 60S ribosomal protein L12 OS=Homo sapiens OX=9606 GN=RPL12 PE=1 SV=1 4.37 2642 - 1.33E+06 - - - 0.5625 - 2.083 0.387 - 120.1 1 2 0 0.0009 16 0 0 0 4.49E+08 3.14E+08 - - - 4.7373 0.9906 221125_WJC_METTL3_EV_vs_WT_F04.14248.14248.3 2.85E-06 13/60 K.EILGTAQSVGC[160.03]NVDGR[166.11].H sp|P30050|RL12_HUMAN 1 1684.8078 1.43 48254 14248 3 1685.80738 562.6099 60S ribosomal protein L12 OS=Homo sapiens OX=9606 GN=RPL12 PE=1 SV=1 4.37 2642.1 - 1.34E+06 - - - 593.2884 - 2.319 0.393 - 200.2 1 2 0 0.9996 16 0 0 0 4.49E+08 3.14E+08 - - - 4.8029 1 221125_WJC_METTL3_EV_vs_WT_F04.14249.14249.2 5.31E-13 18/30 K.EILGTAQSVGC[160.03]NVDGR.H sp|P30050|RL12_HUMAN 1 1674.7995 1.43 48255 14249 2 1674.799987 838.407 60S ribosomal protein L12 OS=Homo sapiens OX=9606 GN=RPL12 PE=1 SV=1 4.37 2642.2 - 1.31E+06 - - - 0.2711 - 3.408 0.714 - 1217.5 1 2 0 0.0005 16 0 0 0 4.70E+08 3.28E+08 - - - 7.3289 1 221125_WJC_METTL3_EV_vs_WT_F04.14250.14250.2 5.62E-07 18/30 K.EILGTAQSVGC[160.03]NVDGR[166.11].H sp|P30050|RL12_HUMAN 1 1684.8078 1.43 48256 14250 2 1684.807514 843.4112 60S ribosomal protein L12 OS=Homo sapiens OX=9606 GN=RPL12 PE=1 SV=1 4.37 2642.4 - 1.16E+06 - - - -0.1715 - 3.387 0.606 - 1123.7 1 2 0 -0.0003 16 0 0 0 4.70E+08 3.28E+08 - - - 6.5161 0.9996 221125_WJC_METTL3_EV_vs_WT_F04.14251.14251.2 0.00155 20-Oct K.ETTIDGEELVK[136.11].L "sp|P52732|KIF11_HUMAN,tr|A0A7I2YQY4|A0A7I2YQY4_HUMAN,tr|A0A7I2V3A9|A0A7I2V3A9_HUMAN,tr|A0A7I2V3V3|A0A7I2V3V3_HUMAN" 4 1240.6278 5.95 48257 14251 2 1240.625816 621.3212 Kinesin-like protein KIF11 OS=Homo sapiens OX=9606 GN=KIF11 PE=1 SV=2 4 2642.5 - 947911 - - - -1.6097 - 1.898 0.401 - 343.7 1 2 0 -0.002 11 0 0 0 5.29E+07 8.89E+06 - - - 3.7357 1 221125_WJC_METTL3_EV_vs_WT_F04.14252.14252.2 8.20E-06 16/22 R.DLDELSRYPEDK.L "sp|P43243|MATR3_HUMAN,tr|A8MXP9|A8MXP9_HUMAN,tr|D6R991|D6R991_HUMAN,tr|A0A0R4J2E8|A0A0R4J2E8_HUMAN,tr|D6REM6|D6REM6_HUMAN" 5 1478.6889 35.13 48258 14252 2 1478.689805 740.3517 Matrin-3 OS=Homo sapiens OX=9606 GN=MATR3 PE=1 SV=2 4.11 2642.6 - 791038 - - - 0.61 - 3.254 0.581 - 910.3 1 2 1 0.0009 12 0 0 0 7.70E+07 2.19E+06 - - - 6.4365 0.9995 221125_WJC_METTL3_EV_vs_WT_F04.14253.14253.2 0.0353 22-Dec R.GEPPLPEEDLSK[136.11].L "sp|O15372|EIF3H_HUMAN,tr|B3KS98|B3KS98_HUMAN,tr|A0A087WZK9|A0A087WZK9_HUMAN" 3 1317.6544 2.26 48259 14253 2 1317.653513 659.8345 Eukaryotic translation initiation factor 3 subunit H OS=Homo sapiens OX=9606 GN=EIF3H PE=1 SV=1 4 2642.7 - 789158 - - - -0.6443 - 1.621 0.373 - 233.4 1 2 0 -0.0008 12 0 0 0 2.87E+07 1.27E+07 - - - 3.0667 1 221125_WJC_METTL3_EV_vs_WT_F04.14254.14254.2 1.92E-06 16/24 K.MDLNSEQAEQLER[166.11].L sp|Q52LJ0|FA98B_HUMAN 1 1571.7125 1.15 48260 14254 2 1571.709043 786.8635 Protein FAM98B OS=Homo sapiens OX=9606 GN=FAM98B PE=1 SV=2 4 2642.9 - 658992 - - - -2.2033 - 3.524 0.598 - 1156 1 2 0 -0.0035 13 0 0 0 2.43E+07 2.12E+07 - - - 6.6895 0.9972 221125_WJC_METTL3_EV_vs_WT_F04.14255.14255.4 0.011 Nov-60 K.IWHHTFYNELR[166.11].V "sp|Q6S8J3|POTEE_HUMAN,sp|P63261|ACTG_HUMAN,sp|P68133|ACTS_HUMAN,sp|Q9BYX7|ACTBM_HUMAN,sp|P68032|ACTC_HUMAN,sp|P60709|ACTB_HUMAN,sp|A5A3E0|POTEF_HUMAN,sp|P0CG38|POTEI_HUMAN,sp|P0CG39|POTEJ_HUMAN,tr|A0A804GS07|A0A804GS07_HUMAN,tr|I3L3I0|I3L3I0_HUMAN,tr|G5E9R0|G5E9R0_HUMAN,tr|E7EVS6|E7EVS6_HUMAN,tr|A0A6Q8PFE4|A0A6Q8PFE4_HUMAN,tr|J3KT65|J3KT65_HUMAN,tr|I3L3R2|I3L3R2_HUMAN,tr|K7EM38|K7EM38_HUMAN,tr|A0A6Q8PH58|A0A6Q8PH58_HUMAN,tr|I3L1U9|I3L1U9_HUMAN,tr|A0A804HKV3|A0A804HKV3_HUMAN,tr|A0A2R8Y793|A0A2R8Y793_HUMAN,tr|I3L4N8|I3L4N8_HUMAN,tr|C9JUM1|C9JUM1_HUMAN,tr|C9JZR7|C9JZR7_HUMAN,tr|A0A2R8YGF8|A0A2R8YGF8_HUMAN,tr|A6NL76|A6NL76_HUMAN" 26 1524.7502 0.01 48261 14255 4 1524.747199 382.1948 POTE ankyrin domain family member E OS=Homo sapiens OX=9606 GN=POTEE PE=2 SV=3 6.92 2643 - 577998 - - - -1.9367 - 2.05 0.26 - 91.5 1 2 0 -0.003 11 0 0 0 7.05E+04 1.25E+07 - - - 1.7661 0.9989 221125_WJC_METTL3_EV_vs_WT_F04.14256.14256.2 0.00814 16-Aug R.NTEYFNQLK.D "sp|Q9H0P0|5NT3A_HUMAN,tr|X6RM59|X6RM59_HUMAN" 2 1155.556 0.76 48262 14256 2 1155.557668 578.7853 Cytosolic 5'-nucleotidase 3A OS=Homo sapiens OX=9606 GN=NT5C3A PE=1 SV=3 6 2643.1 - 553899 - - - 1.4106 - 1.589 0.315 - 283.4 1 2 0 0.0016 9 0 0 0 4.91E+06 6.44E+06 - - - 2.7069 1 221125_WJC_METTL3_EV_vs_WT_F04.14257.14257.2 8.84E-07 15/22 R.K[136.11]VFDPVPVGVTK[136.11].V sp|Q08211|DHX9_HUMAN 1 1300.7726 0.86 48263 14257 2 1300.774514 651.3936 ATP-dependent RNA helicase A OS=Homo sapiens OX=9606 GN=DHX9 PE=1 SV=4 8.59 2643.3 - 453395 - - - 1.4914 - 3.067 0.608 - 593.5 1 2 0 0.0019 12 0 0 0 1.63E+07 1.89E+07 - - - 6.4798 0.9999 221125_WJC_METTL3_EV_vs_WT_F04.14258.14258.3 1.35E-05 15/48 K.NAQLNIELEAAHH.- "sp|P43490|NAMPT_HUMAN,tr|A0A7P0T862|A0A7P0T862_HUMAN,tr|A0A7P0T931|A0A7P0T931_HUMAN,tr|A0A7P0T973|A0A7P0T973_HUMAN,tr|A0A7P0T895|A0A7P0T895_HUMAN,tr|A0A7P0Z437|A0A7P0Z437_HUMAN,tr|A0A7P0T9I9|A0A7P0T9I9_HUMAN" 7 1458.7215 - 48264 14258 3 1458.723652 487.2478 Nicotinamide phosphoribosyltransferase OS=Homo sapiens OX=9606 GN=NAMPT PE=1 SV=1 5.23 2643.4 - 421378 - - - 1.4472 - 2.887 0.421 - 340.3 1 2 0 0.0021 13 0 0 0 - - - - - 6.1077 1 221125_WJC_METTL3_EV_vs_WT_F04.14261.14261.2 1.08E-07 15/22 R.KVFDPVPVGVTK.V sp|Q08211|DHX9_HUMAN 1 1284.7442 0.86 48267 14261 2 1284.74952 643.3794 ATP-dependent RNA helicase A OS=Homo sapiens OX=9606 GN=DHX9 PE=1 SV=4 8.59 2643.8 - 248783 - - - 4.1611 - 2.727 0.587 - 579.9 1 2 0 0.0053 12 0 0 0 1.63E+07 1.89E+07 - - - 6.0145 0.9999 221125_WJC_METTL3_EV_vs_WT_F04.14263.14263.3 0.00119 14/44 K.YPSLLLHSQEEK.T "sp|Q8IWZ3|ANKH1_HUMAN,tr|A0A0A0MQZ8|A0A0A0MQZ8_HUMAN,tr|H0Y472|H0Y472_HUMAN,tr|H0Y7Y3|H0Y7Y3_HUMAN,tr|H0Y4P6|H0Y4P6_HUMAN,tr|H0Y785|H0Y785_HUMAN" 6 1442.7405 1.37 48268 14263 3 1442.741311 481.9208 Ankyrin repeat and KH domain-containing protein 1 OS=Homo sapiens OX=9606 GN=ANKHD1 PE=1 SV=1 5.4 2644 - 1.49E+06 - - - 0.5309 - 2.637 0.398 - 164.3 1 2 0 0.0008 12 0 0 0 1.77E+07 1.30E+07 - - - 5.6648 0.9985 221125_WJC_METTL3_EV_vs_WT_F04.14265.14265.3 0.033 14/44 R.K[136.11]VFDPVPVGVTK[136.11].V sp|Q08211|DHX9_HUMAN 1 1300.7726 0.9 48270 14265 3 1300.773403 434.5981 ATP-dependent RNA helicase A OS=Homo sapiens OX=9606 GN=DHX9 PE=1 SV=4 8.59 2644.2 - 2.47E+06 - - - 0.6373 - 2.067 0.22 - 233.7 1 2 0 0.0008 12 0 0 0 4.54E+07 5.06E+07 - - - 3.0052 1 221125_WJC_METTL3_EV_vs_WT_F04.14266.14266.2 5.05E-07 13/24 K.MDLNSEQAEQLER.L sp|Q52LJ0|FA98B_HUMAN 1 1561.7042 1.15 48271 14266 2 1561.703992 781.8594 Protein FAM98B OS=Homo sapiens OX=9606 GN=FAM98B PE=1 SV=2 4 2644.3 - 1.58E+06 - - - -0.1562 - 3.055 0.639 - 634.6 1 2 0 -0.0002 13 0 0 0 2.43E+07 2.12E+07 - - - 6.6268 0.9999 221125_WJC_METTL3_EV_vs_WT_F04.14267.14267.3 1.37E-06 14/48 R.GRAPQVLVLAPTR.E sp|Q9NR30|DDX21_HUMAN 1 1376.8252 0.91 48272 14267 3 1376.826378 459.949 Nucleolar RNA helicase 2 OS=Homo sapiens OX=9606 GN=DDX21 PE=1 SV=5 12 2644.3 - 1.54E+06 - - - 0.8425 - 2.769 0.573 - 323.7 1 2 1 0.0012 13 0 0 0 2.27E+07 2.49E+07 - - - 7.6895 0.9999 221125_WJC_METTL3_EV_vs_WT_F04.14268.14268.2 0.00414 24-Dec R.DLTTAGAVTQC[160.03]YR.D "sp|Q02543|RL18A_HUMAN,tr|M0R3D6|M0R3D6_HUMAN,tr|M0R0P7|M0R0P7_HUMAN,tr|M0R117|M0R117_HUMAN,tr|M0R1A7|M0R1A7_HUMAN" 5 1454.6824 0.77 48273 14268 2 1454.682334 728.3485 60S ribosomal protein L18a OS=Homo sapiens OX=9606 GN=RPL18A PE=1 SV=2 5.83 2644.4 - 1.51E+06 - - - -0.0302 - 2.485 0.506 - 466.9 1 2 0 0 13 0 0 0 3.03E+07 3.93E+07 - - - 5.1145 0.9974 221125_WJC_METTL3_EV_vs_WT_F04.14269.14269.3 0.0265 13/40 R.YGSR[166.11]PVWADYR[166.11].R "sp|Q9Y676|RT18B_HUMAN,tr|A0A0G2JIC6|A0A0G2JIC6_HUMAN" 2 1388.674 2.97 48274 14269 3 1388.674252 463.8986 "28S ribosomal protein S18b, mitochondrial OS=Homo sapiens OX=9606 GN=MRPS18B PE=1 SV=1" 8.59 2644.5 - 764812 - - - 0.1642 - 1.744 0.227 - 157.5 1 2 0 0.0002 11 0 0 0 2.54E+07 8.55E+06 - - - 2.6508 1 221125_WJC_METTL3_EV_vs_WT_F04.14270.14270.2 5.16E-08 13/24 Y.AYVNFQQPADAER[166.11].A "sp|Q13310|PABP4_HUMAN,sp|P11940|PABP1_HUMAN,tr|A0A7I2V649|A0A7I2V649_HUMAN,tr|B1ANR0|B1ANR0_HUMAN,tr|A0A7I2V4L7|A0A7I2V4L7_HUMAN,tr|E5RHG7|E5RHG7_HUMAN,tr|B1ANR1|B1ANR1_HUMAN,tr|H0YAR2|H0YAR2_HUMAN,tr|E7ERJ7|E7ERJ7_HUMAN,tr|E5RJB9|E5RJB9_HUMAN,tr|A0A7I2YQ88|A0A7I2YQ88_HUMAN,tr|E5RH24|E5RH24_HUMAN,tr|H0YBN4|H0YBN4_HUMAN,tr|E5RGH3|E5RGH3_HUMAN,tr|A0A087WTT1|A0A087WTT1_HUMAN,tr|A0A7I2YQ90|A0A7I2YQ90_HUMAN,tr|E7EQV3|E7EQV3_HUMAN" 17 1517.7138 0.65 48275 14270 2 1517.7151 759.8642 Polyadenylate-binding protein 4 OS=Homo sapiens OX=9606 GN=PABPC4 PE=1 SV=1 4.37 2644.6 - 616182 - - - 0.8394 - 2.34 0.614 - 321.6 1 1 0 0.0013 13 0 0 0 8.14E+06 1.25E+07 - - - 5.7575 0.9998 221125_WJC_METTL3_EV_vs_WT_F04.14271.14271.2 3.39E-06 24-Sep K.ETEYQALQETNMK[136.11].F "sp|Q15643|TRIPB_HUMAN,tr|H0YJ97|H0YJ97_HUMAN" 2 1591.7279 1.96 48276 14271 2 1591.729047 796.8712 Thyroid receptor-interacting protein 11 OS=Homo sapiens OX=9606 GN=TRIP11 PE=1 SV=3 4.25 2644.7 - 505604 - - - 0.6967 - 2.063 0.466 - 249.2 1 2 0 0.0011 13 0 0 0 9.92E+06 5.06E+06 - - - 4.3411 0.9998 221125_WJC_METTL3_EV_vs_WT_F04.14275.14275.2 6.06E-05 20-Nov R.EEAENTLQSFR[166.11].Q "sp|P08670|VIME_HUMAN,tr|B0YJC5|B0YJC5_HUMAN,tr|B0YJC4|B0YJC4_HUMAN" 3 1332.6185 1.96 48279 14275 2 1332.619231 667.3165 Vimentin OS=Homo sapiens OX=9606 GN=VIM PE=1 SV=4 4.25 2645.2 - 1.54E+06 - - - 0.5268 - 2.098 0.478 - 549.7 1 2 0 0.0007 11 0 0 0 2.44E+09 1.24E+09 - - - 4.5758 0.9818 221125_WJC_METTL3_EV_vs_WT_F04.14277.14277.2 0.00053 22-Jul K.DHTPSQELALTQ.S "sp|Q86U44|MTA70_HUMAN,tr|H0YFV6|H0YFV6_HUMAN" 2 1338.6416 - 48280 14277 2 1338.642678 670.3281 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 4.35 2645.5 - 3.39E+06 - - - 0.8359 - 1.745 0.445 - 174.6 1 1 0 0.0011 12 0 0 0 - - - - - 3.7923 1 221125_WJC_METTL3_EV_vs_WT_F04.14278.14278.3 0.000145 Dec-44 R.KVFDPVPVGVTK.V sp|Q08211|DHX9_HUMAN 1 1284.7442 0.9 48281 14278 3 1284.744967 429.2553 ATP-dependent RNA helicase A OS=Homo sapiens OX=9606 GN=DHX9 PE=1 SV=4 8.59 2645.5 - 2.97E+06 - - - 0.6172 - 2.226 0.507 - 270 1 2 0 0.0008 12 0 0 0 4.55E+07 5.08E+07 - - - 6.4104 1 221125_WJC_METTL3_EV_vs_WT_F04.14279.14279.2 2.72E-07 13/24 R.DLTTAGAVTQC[160.03]YR[166.11].D "sp|Q02543|RL18A_HUMAN,tr|M0R3D6|M0R3D6_HUMAN,tr|M0R0P7|M0R0P7_HUMAN,tr|M0R117|M0R117_HUMAN,tr|M0R1A7|M0R1A7_HUMAN" 5 1464.6906 0.77 48282 14279 2 1464.692717 733.3526 60S ribosomal protein L18a OS=Homo sapiens OX=9606 GN=RPL18A PE=1 SV=2 5.83 2645.6 - 3.00E+06 - - - 1.4126 - 2.547 0.601 - 532.2 1 2 0 0.0021 13 0 0 0 3.03E+07 3.93E+07 - - - 5.8788 0.9999 221125_WJC_METTL3_EV_vs_WT_F04.14280.14280.3 0.00331 Dec-40 K.IWHHTFYNELR[166.11].V "sp|Q6S8J3|POTEE_HUMAN,sp|P63261|ACTG_HUMAN,sp|P68133|ACTS_HUMAN,sp|Q9BYX7|ACTBM_HUMAN,sp|P68032|ACTC_HUMAN,sp|P60709|ACTB_HUMAN,sp|A5A3E0|POTEF_HUMAN,sp|P0CG38|POTEI_HUMAN,sp|P0CG39|POTEJ_HUMAN,tr|A0A804GS07|A0A804GS07_HUMAN,tr|I3L3I0|I3L3I0_HUMAN,tr|G5E9R0|G5E9R0_HUMAN,tr|E7EVS6|E7EVS6_HUMAN,tr|A0A6Q8PFE4|A0A6Q8PFE4_HUMAN,tr|J3KT65|J3KT65_HUMAN,tr|I3L3R2|I3L3R2_HUMAN,tr|K7EM38|K7EM38_HUMAN,tr|A0A6Q8PH58|A0A6Q8PH58_HUMAN,tr|I3L1U9|I3L1U9_HUMAN,tr|A0A804HKV3|A0A804HKV3_HUMAN,tr|A0A2R8Y793|A0A2R8Y793_HUMAN,tr|I3L4N8|I3L4N8_HUMAN,tr|C9JUM1|C9JUM1_HUMAN,tr|C9JZR7|C9JZR7_HUMAN,tr|A0A2R8YGF8|A0A2R8YGF8_HUMAN,tr|A6NL76|A6NL76_HUMAN" 26 1524.7502 0.93 48283 14280 3 1524.750209 509.2573 POTE ankyrin domain family member E OS=Homo sapiens OX=9606 GN=POTEE PE=2 SV=3 6.92 2645.6 - 2.20E+06 - - - 0.0374 - 2.395 0.408 - 254.6 1 2 0 0.0001 11 0 0 0 4.03E+07 4.33E+07 - - - 5.5699 0.9999 221125_WJC_METTL3_EV_vs_WT_F04.14281.14281.3 0.00034 Nov-40 K.IWHHTFYNELR.V "sp|Q6S8J3|POTEE_HUMAN,sp|P63261|ACTG_HUMAN,sp|P68133|ACTS_HUMAN,sp|Q9BYX7|ACTBM_HUMAN,sp|P68032|ACTC_HUMAN,sp|P60709|ACTB_HUMAN,sp|A5A3E0|POTEF_HUMAN,sp|P0CG38|POTEI_HUMAN,sp|P0CG39|POTEJ_HUMAN,tr|A0A804GS07|A0A804GS07_HUMAN,tr|I3L3I0|I3L3I0_HUMAN,tr|G5E9R0|G5E9R0_HUMAN,tr|E7EVS6|E7EVS6_HUMAN,tr|A0A6Q8PFE4|A0A6Q8PFE4_HUMAN,tr|J3KT65|J3KT65_HUMAN,tr|I3L3R2|I3L3R2_HUMAN,tr|K7EM38|K7EM38_HUMAN,tr|A0A6Q8PH58|A0A6Q8PH58_HUMAN,tr|I3L1U9|I3L1U9_HUMAN,tr|A0A804HKV3|A0A804HKV3_HUMAN,tr|A0A2R8Y793|A0A2R8Y793_HUMAN,tr|I3L4N8|I3L4N8_HUMAN,tr|C9JUM1|C9JUM1_HUMAN,tr|C9JZR7|C9JZR7_HUMAN,tr|A0A2R8YGF8|A0A2R8YGF8_HUMAN,tr|A6NL76|A6NL76_HUMAN" 26 1514.7419 0.93 48284 14281 3 1514.743886 505.9212 POTE ankyrin domain family member E OS=Homo sapiens OX=9606 GN=POTEE PE=2 SV=3 6.92 2645.7 - 1.85E+06 - - - 1.323 - 2.256 0.471 - 202.1 1 2 0 0.002 11 0 0 0 3.99E+07 4.31E+07 - - - 6.1019 0.9999 221125_WJC_METTL3_EV_vs_WT_F04.14284.14284.3 2.71E-05 Oct-44 K.TEELEEESFPER[166.11].S "sp|Q9Y2W1|TR150_HUMAN,tr|A0A3B3ITZ9|A0A3B3ITZ9_HUMAN" 2 1503.6605 2.7 48287 14284 3 1503.660354 502.2274 Thyroid hormone receptor-associated protein 3 OS=Homo sapiens OX=9606 GN=THRAP3 PE=1 SV=2 3.9 2646 - 835439 - - - -0.0658 - 2.018 0.485 - 140.8 1 2 0 -0.0001 12 0 0 0 1.99E+08 7.35E+07 - - - 5.8934 1 221125_WJC_METTL3_EV_vs_WT_F04.14288.14288.2 5.21E-06 18/30 R.AITDGQAGFGNDTLSK[136.11].V "sp|Q7Z739|YTHD3_HUMAN,tr|A0A087X0Q1|A0A087X0Q1_HUMAN,tr|A0A024R7W5|A0A024R7W5_HUMAN,tr|A0A087WY31|A0A087WY31_HUMAN" 4 1601.7777 1.34 48291 14288 2 1601.775733 801.8961 YTH domain-containing family protein 3 OS=Homo sapiens OX=9606 GN=YTHDF3 PE=1 SV=1 4.21 2646.4 - 592541 - - - -1.2062 - 3.647 0.561 - 906.8 1 2 0 -0.0019 16 0 0 0 1.46E+08 1.09E+08 - - - 6.3651 0.9978 221125_WJC_METTL3_EV_vs_WT_F04.14295.14295.3 0.0275 Sep-40 K.QFEDELHPDLK[136.11].F sp|Q9Y3C6|PPIL1_HUMAN 1 1377.6656 1.28 48296 14295 3 1377.664926 460.2291 Peptidyl-prolyl cis-trans isomerase-like 1 OS=Homo sapiens OX=9606 GN=PPIL1 PE=1 SV=1 4.31 2647.3 - 2.30E+06 - - - -0.4856 - 1.36 0.302 - 105.1 1 2 0 -0.0007 11 0 0 0 5.99E+07 4.70E+07 - - - 2.7803 1 221125_WJC_METTL3_EV_vs_WT_F04.14296.14296.2 8.82E-07 15/30 R.AITDGQAGFGNDTLSK.V "sp|Q7Z739|YTHD3_HUMAN,tr|A0A087X0Q1|A0A087X0Q1_HUMAN,tr|A0A024R7W5|A0A024R7W5_HUMAN,tr|A0A087WY31|A0A087WY31_HUMAN" 4 1593.7635 1.35 48297 14296 2 1593.76705 797.889 YTH domain-containing family protein 3 OS=Homo sapiens OX=9606 GN=YTHDF3 PE=1 SV=1 4.21 2647.4 - 1.54E+06 - - - 2.2494 - 3.284 0.584 - 622.2 1 2 0 0.0036 16 0 0 0 1.46E+08 1.09E+08 - - - 6.2767 0.9999 221125_WJC_METTL3_EV_vs_WT_F04.14299.14299.3 0.000563 18/52 R.LAELLTQQHGLQC[160.03]R.A "sp|Q9H6R4|NOL6_HUMAN,tr|A0A0A0MRW6|A0A0A0MRW6_HUMAN" 2 1665.8621 1.06 48300 14299 3 1665.862934 556.2946 Nucleolar protein 6 OS=Homo sapiens OX=9606 GN=NOL6 PE=1 SV=2 6.74 2647.8 - 674817 - - - 0.5162 - 2.353 0.388 - 329.8 1 2 0 0.0009 14 0 0 0 8.46E+06 7.97E+06 - - - 5.1396 0.9993 221125_WJC_METTL3_EV_vs_WT_F04.14300.14300.3 0.00134 13/40 R.LLASTLVHSVK.K "sp|Q9NYF8|BCLF1_HUMAN,tr|E9PKI6|E9PKI6_HUMAN,tr|A0A1W2PQ43|A0A1W2PQ43_HUMAN,tr|E9PK91|E9PK91_HUMAN,tr|E9PJA7|E9PJA7_HUMAN,tr|E9PK09|E9PK09_HUMAN,tr|E9PQN2|E9PQN2_HUMAN" 7 1166.7023 2.06 48301 14300 3 1166.700876 389.908 Bcl-2-associated transcription factor 1 OS=Homo sapiens OX=9606 GN=BCLAF1 PE=1 SV=2 8.76 2647.9 - 636773 - - - -1.2282 - 2.435 0.229 - 107.1 1 2 0 -0.0014 11 0 0 0 1.12E+08 5.47E+07 - - - 3.6209 0.9975 221125_WJC_METTL3_EV_vs_WT_F04.14301.14301.3 0.0328 Nov-36 R.RIDISPSTFR.K "sp|Q9Y2W1|TR150_HUMAN,tr|A0A3B3ITZ9|A0A3B3ITZ9_HUMAN" 2 1190.6408 2.46 48302 14301 3 1190.63551 397.8875 Thyroid hormone receptor-associated protein 3 OS=Homo sapiens OX=9606 GN=THRAP3 PE=1 SV=2 9.6 2648 - 344708 - - - -4.4186 - 2.189 0.321 - 282.8 1 2 0 -0.0053 10 0 0 0 3.20E+08 1.30E+08 - - - 4.4054 0.9781 221125_WJC_METTL3_EV_vs_WT_F04.14303.14303.3 0.0218 Aug-48 K.MDLNSEQAEQLER[166.11].L sp|Q52LJ0|FA98B_HUMAN 1 1571.7125 2.34 48304 14303 3 1571.70984 524.9114 Protein FAM98B OS=Homo sapiens OX=9606 GN=FAM98B PE=1 SV=2 4 2648.3 - 252308 - - - -1.6962 - 1.479 0.176 - 84.3 1 2 0 -0.0027 13 0 0 0 6.04E+06 2.58E+06 - - - 1.5626 0.9999 221125_WJC_METTL3_EV_vs_WT_F04.14309.14309.3 0.00189 15/40 R.LLASTLVHSVK[136.11].K "sp|Q9NYF8|BCLF1_HUMAN,tr|E9PKI6|E9PKI6_HUMAN,tr|A0A1W2PQ43|A0A1W2PQ43_HUMAN,tr|E9PK91|E9PK91_HUMAN,tr|E9PJA7|E9PJA7_HUMAN,tr|E9PK09|E9PK09_HUMAN,tr|E9PQN2|E9PQN2_HUMAN" 7 1174.7165 2.05 48308 14309 3 1174.71482 392.5794 Bcl-2-associated transcription factor 1 OS=Homo sapiens OX=9606 GN=BCLAF1 PE=1 SV=2 8.76 2649 - 632961 - - - -1.4378 - 2.522 0.346 - 179.7 1 2 0 -0.0017 11 0 0 0 1.12E+08 5.48E+07 - - - 5.025 0.8993 221125_WJC_METTL3_EV_vs_WT_F04.14311.14311.2 0.00037 26-Aug R.INSDDSNLYLTASK.K "sp|Q9BZG1|RAB34_HUMAN,tr|C9JY26|C9JY26_HUMAN" 2 1539.7417 14.47 48310 14311 2 1540.749494 770.8781 Ras-related protein Rab-34 OS=Homo sapiens OX=9606 GN=RAB34 PE=1 SV=1 4.21 2649.3 - 383013 - - - 654.5429 - 1.679 0.374 - 132.6 1 2 0 1.0078 14 0 0 0 6.69E+07 4.62E+06 - - - 2.7873 0.9999 221125_WJC_METTL3_EV_vs_WT_F04.14312.14312.3 1.03E-05 Nov-60 R.AITDGQAGFGNDTLSK.V "sp|Q7Z739|YTHD3_HUMAN,tr|A0A087X0Q1|A0A087X0Q1_HUMAN,tr|A0A024R7W5|A0A024R7W5_HUMAN,tr|A0A087WY31|A0A087WY31_HUMAN" 4 1593.7635 1.23 48311 14312 3 1593.766742 532.2618 YTH domain-containing family protein 3 OS=Homo sapiens OX=9606 GN=YTHDF3 PE=1 SV=1 4.21 2649.4 - 355433 - - - 2.0561 - 2.294 0.526 - 116.6 1 2 0 0.0033 16 0 0 0 1.08E+07 8.78E+06 - - - 6.5339 0.9999 221125_WJC_METTL3_EV_vs_WT_F04.14315.14315.2 6.43E-07 14/24 R.EGVVQGVASVAEK.T sp|Q16143|SYUB_HUMAN 1 1271.6721 1.46 48312 14315 2 1271.671758 636.8433 Beta-synuclein OS=Homo sapiens OX=9606 GN=SNCB PE=1 SV=1 4.53 2649.8 - 958317 - - - -0.2933 - 2.493 0.506 - 811.9 1 2 0 -0.0004 13 0 0 0 6.86E+08 4.70E+08 - - - 5.1227 1 221125_WJC_METTL3_EV_vs_WT_F04.14317.14317.4 2.60E-07 16/78 R.LVHPGVAEVVFVKK.D "sp|Q9BY77|PDIP3_HUMAN,tr|F6VRR5|F6VRR5_HUMAN" 2 1520.9079 1.28 48314 14317 4 1520.905783 381.2342 Polymerase delta-interacting protein 3 OS=Homo sapiens OX=9606 GN=POLDIP3 PE=1 SV=2 8.6 2650 - 1.28E+06 - - - -1.3821 - 2.933 0.511 - 217.9 1 2 0 -0.0021 14 0 0 0 3.38E+07 2.63E+07 - - - 4.0648 1 221125_WJC_METTL3_EV_vs_WT_F04.14318.14318.4 2.03E-07 13/78 R.LVHPGVAEVVFVK[136.11]K[136.11].D "sp|Q9BY77|PDIP3_HUMAN,tr|F6VRR5|F6VRR5_HUMAN" 2 1536.9363 1.32 48315 14318 4 1536.933797 385.2413 Polymerase delta-interacting protein 3 OS=Homo sapiens OX=9606 GN=POLDIP3 PE=1 SV=2 8.6 2650.1 - 822377 - - - -1.6188 - 2.401 0.568 - 116 1 2 0 -0.0025 14 0 0 0 3.37E+07 2.55E+07 - - - 4.488 1 221125_WJC_METTL3_EV_vs_WT_F04.14321.14321.3 4.16E-07 14/60 R.AITDGQAGFGNDTLSK[136.11].V "sp|Q7Z739|YTHD3_HUMAN,tr|A0A087X0Q1|A0A087X0Q1_HUMAN,tr|A0A024R7W5|A0A024R7W5_HUMAN,tr|A0A087WY31|A0A087WY31_HUMAN" 4 1601.7777 1.24 48318 14321 3 1601.774649 534.9332 YTH domain-containing family protein 3 OS=Homo sapiens OX=9606 GN=YTHDF3 PE=1 SV=1 4.21 2650.5 - 659480 - - - -1.8829 - 2.444 0.565 - 211 1 2 0 -0.003 16 0 0 0 1.10E+07 8.84E+06 - - - 7.1313 0.9993 221125_WJC_METTL3_EV_vs_WT_F04.14322.14322.2 0.071 20-Oct R.LLASTLVHSVK.K "sp|Q9NYF8|BCLF1_HUMAN,tr|E9PKI6|E9PKI6_HUMAN,tr|A0A1W2PQ43|A0A1W2PQ43_HUMAN,tr|E9PK91|E9PK91_HUMAN,tr|E9PJA7|E9PJA7_HUMAN,tr|E9PK09|E9PK09_HUMAN,tr|E9PQN2|E9PQN2_HUMAN" 7 1166.7023 2.19 48319 14322 2 1166.702042 584.3584 Bcl-2-associated transcription factor 1 OS=Homo sapiens OX=9606 GN=BCLAF1 PE=1 SV=2 8.76 2650.6 - 644443 - - - -0.2289 - 2.054 0.228 - 262.9 1 2 0 -0.0003 11 0 0 0 3.51E+07 1.60E+07 - - - 2.6721 1 221125_WJC_METTL3_EV_vs_WT_F04.14323.14323.2 6.07E-06 15/18 L.DELSRYPEDK.L "sp|P43243|MATR3_HUMAN,tr|A8MXP9|A8MXP9_HUMAN,tr|D6R991|D6R991_HUMAN,tr|A0A0R4J2E8|A0A0R4J2E8_HUMAN,tr|D6REM6|D6REM6_HUMAN" 5 1250.5779 0.37 48320 14323 2 1250.580692 626.2962 Matrin-3 OS=Homo sapiens OX=9606 GN=MATR3 PE=1 SV=2 4.32 2650.8 - 388467 - - - 2.2358 - 3.041 0.562 - 1337.4 1 1 1 0.0028 10 0 0 0 7.88E+06 2.14E+07 - - - 6.2955 1 221125_WJC_METTL3_EV_vs_WT_F04.14324.14324.3 5.49E-11 20/52 R.LVHPGVAEVVFVK[136.11]K[136.11].D "sp|Q9BY77|PDIP3_HUMAN,tr|F6VRR5|F6VRR5_HUMAN" 2 1536.9363 1.2 48321 14324 3 1536.934101 513.3194 Polymerase delta-interacting protein 3 OS=Homo sapiens OX=9606 GN=POLDIP3 PE=1 SV=2 8.6 2650.9 - 372790 - - - -1.421 - 3.431 0.694 - 538 1 2 0 -0.0022 14 0 0 0 1.76E+07 1.46E+07 - - - 9.5532 0.9998 221125_WJC_METTL3_EV_vs_WT_F04.14326.14326.2 7.52E-07 22-Sep K.TFNPGAGLPTDK.K "sp|P09661|RU2A_HUMAN,tr|H0YMA0|H0YMA0_HUMAN,tr|H0YLR3|H0YLR3_HUMAN" 3 1216.6088 1.24 48322 14326 2 1216.60722 609.3117 U2 small nuclear ribonucleoprotein A' OS=Homo sapiens OX=9606 GN=SNRPA1 PE=1 SV=2 5.5 2651.1 - 1.32E+06 - - - -1.3003 - 2.075 0.514 - 164.3 1 2 0 -0.0016 12 0 0 0 4.23E+07 3.41E+07 - - - 4.7576 0.9998 221125_WJC_METTL3_EV_vs_WT_F04.14327.14327.2 2.17E-05 22-Oct K.TFNPGAGLPTDK[136.11].K "sp|P09661|RU2A_HUMAN,tr|H0YMA0|H0YMA0_HUMAN,tr|H0YLR3|H0YLR3_HUMAN" 3 1224.623 1.24 48323 14327 2 1224.621105 613.3188 U2 small nuclear ribonucleoprotein A' OS=Homo sapiens OX=9606 GN=SNRPA1 PE=1 SV=2 5.5 2651.2 - 774153 - - - -1.549 - 1.917 0.515 - 255.9 1 2 0 -0.0019 12 0 0 0 4.21E+07 3.39E+07 - - - 4.5565 0.9999 221125_WJC_METTL3_EV_vs_WT_F04.14328.14328.2 1.16E-06 13/24 R.EGVVQGVASVAEK[136.11].T sp|Q16143|SYUB_HUMAN 1 1279.6863 1.46 48324 14328 2 1279.685081 640.8504 Beta-synuclein OS=Homo sapiens OX=9606 GN=SNCB PE=1 SV=1 4.53 2651.3 - 2.38E+06 - - - -0.9768 - 2.491 0.537 - 761.2 1 2 0 -0.0013 13 0 0 0 6.86E+08 4.70E+08 - - - 5.3493 0.988 221125_WJC_METTL3_EV_vs_WT_F04.14332.14332.2 0.000572 13/20 V.NGR[166.11]PLEMIEPR[166.11].T "sp|P62249|RS16_HUMAN,tr|M0R3H0|M0R3H0_HUMAN,tr|M0R1M5|M0R1M5_HUMAN,tr|Q6IPX4|Q6IPX4_HUMAN" 4 1330.693 0.07 48328 14332 2 1330.692947 666.3538 40S ribosomal protein S16 OS=Homo sapiens OX=9606 GN=RPS16 PE=1 SV=2 6.14 2651.8 - 778319 - - - -0.0736 - 2.117 0.405 - 380.5 1 1 0 -0.0001 11 0 0 0 3.57E+05 5.31E+06 - - - 4.0612 0.9997 221125_WJC_METTL3_EV_vs_WT_F04.14334.14334.2 6.61E-05 22-Oct R.VQQQEDEITVLK[136.11].A "sp|Q9HC35|EMAL4_HUMAN,tr|B5MBZ0|B5MBZ0_HUMAN" 2 1436.7602 0.93 48330 14334 2 1436.760707 719.3874 Echinoderm microtubule-associated protein-like 4 OS=Homo sapiens OX=9606 GN=EML4 PE=1 SV=3 4.14 2652.1 - 586887 - - - 0.3362 - 1.969 0.365 - 295.5 1 2 0 0.0005 12 0 0 0 6.58E+06 7.10E+06 - - - 3.5194 0.9996 221125_WJC_METTL3_EV_vs_WT_F04.14337.14337.2 0.000569 20-Jul K.QFEDELHPDLK.F sp|Q9Y3C6|PPIL1_HUMAN 1 1369.6514 1.9 48333 14337 2 1369.650454 685.833 Peptidyl-prolyl cis-trans isomerase-like 1 OS=Homo sapiens OX=9606 GN=PPIL1 PE=1 SV=1 4.31 2652.5 - 457624 - - - -0.687 - 1.764 0.373 - 193.6 1 2 0 -0.0009 11 0 0 0 3.46E+06 1.82E+06 - - - 3.3311 0.9999 221125_WJC_METTL3_EV_vs_WT_F04.14340.14340.3 2.67E-05 14/44 K.YPSLLLHSQEEK[136.11].T "sp|Q8IWZ3|ANKH1_HUMAN,tr|A0A0A0MQZ8|A0A0A0MQZ8_HUMAN,tr|H0Y472|H0Y472_HUMAN,tr|H0Y7Y3|H0Y7Y3_HUMAN,tr|H0Y4P6|H0Y4P6_HUMAN,tr|H0Y785|H0Y785_HUMAN" 6 1450.7547 1.62 48335 14340 3 1450.753757 484.5922 Ankyrin repeat and KH domain-containing protein 1 OS=Homo sapiens OX=9606 GN=ANKHD1 PE=1 SV=1 5.4 2652.8 - 1.54E+06 - - - -0.681 - 2.132 0.463 - 142.4 1 2 0 -0.001 12 0 0 0 5.75E+07 3.55E+07 - - - 5.8002 0.8749 221125_WJC_METTL3_EV_vs_WT_F04.14341.14341.3 0.391 14/44 K.GGFLPPEEIK[136.11]ER[166.11].F sp|Q9H0D6|XRN2_HUMAN 1 1388.7419 0.83 48336 14341 3 1389.744546 463.9212 5'-3' exoribonuclease 2 OS=Homo sapiens OX=9606 GN=XRN2 PE=1 SV=1 4.79 2652.9 - 823560 - - - 721.9923 - 2.069 0.258 - 224.8 1 2 1 1.0027 12 0 0 0 1.32E+07 1.59E+07 - - - 3.154 0.9999 221125_WJC_METTL3_EV_vs_WT_F04.14342.14342.3 3.59E-05 Dec-40 K.HFSGLEEAVYR[166.11].N "sp|P50990|TCPQ_HUMAN,tr|H7C4C8|H7C4C8_HUMAN" 2 1316.6389 0.35 48337 14342 3 1316.637169 439.8869 T-complex protein 1 subunit theta OS=Homo sapiens OX=9606 GN=CCT8 PE=1 SV=4 5.4 2653 - 9.76E+06 - - - -1.2919 - 2.421 0.447 - 349.5 1 2 0 -0.0017 11 0 0 0 1.98E+08 5.67E+08 - - - 6.0349 1 221125_WJC_METTL3_EV_vs_WT_F04.14343.14343.3 5.72E-07 Dec-44 K.TEELEEESFPER.S "sp|Q9Y2W1|TR150_HUMAN,tr|A0A3B3ITZ9|A0A3B3ITZ9_HUMAN" 2 1493.6522 2.7 48338 14343 3 1493.650486 498.8913 Thyroid hormone receptor-associated protein 3 OS=Homo sapiens OX=9606 GN=THRAP3 PE=1 SV=2 3.9 2653 - 6.52E+06 - - - -1.1361 - 2.307 0.582 - 209.2 1 2 0 -0.0017 12 0 0 0 1.99E+08 7.35E+07 - - - 7.3454 1 221125_WJC_METTL3_EV_vs_WT_F04.14344.14344.3 1.63E-05 13/40 K.HFSGLEEAVYR.N "sp|P50990|TCPQ_HUMAN,tr|H7C4C8|H7C4C8_HUMAN" 2 1306.6306 0.35 48339 14344 3 1306.629457 436.5508 T-complex protein 1 subunit theta OS=Homo sapiens OX=9606 GN=CCT8 PE=1 SV=4 5.4 2653.1 - 2.90E+06 - - - -0.8748 - 2.652 0.427 - 384.4 1 2 0 -0.0011 11 0 0 0 1.98E+08 5.67E+08 - - - 6.071 0.999 221125_WJC_METTL3_EV_vs_WT_F04.14346.14346.3 0.122 Oct-40 R.ERPAAIPIEIK.S sp|Q9Y2H1|ST38L_HUMAN 1 1235.7238 3.72 48341 14346 3 1235.72169 412.9152 Serine\threonine-protein kinase 38-like OS=Homo sapiens OX=9606 GN=STK38L PE=1 SV=3 6.24 2653.2 - 2.07E+06 - - - -1.6848 - 1.882 0.29 - 135.1 1 2 0 -0.0021 11 0 0 0 1.82E+08 4.89E+07 - - - 3.569 0.9654 221125_WJC_METTL3_EV_vs_WT_F04.14347.14347.3 0.00418 Dec-40 Q.WLPDVTRPEGK.D "sp|Q09028|RBBP4_HUMAN,tr|E9PND5|E9PND5_HUMAN,tr|C9JPP3|C9JPP3_HUMAN,tr|E9PNS6|E9PNS6_HUMAN" 4 1296.6826 2 48342 14347 3 1296.681202 433.2348 Histone-binding protein RBBP4 OS=Homo sapiens OX=9606 GN=RBBP4 PE=1 SV=3 6.07 2653.2 - 1.81E+06 - - - -1.1059 - 2.178 0.306 - 222.4 1 1 0 -0.0014 11 0 0 0 1.47E+07 7.36E+06 - - - 4.1625 1 221125_WJC_METTL3_EV_vs_WT_F04.14348.14348.3 3.71E-06 18/52 R.LVHPGVAEVVFVKK.D "sp|Q9BY77|PDIP3_HUMAN,tr|F6VRR5|F6VRR5_HUMAN" 2 1520.9079 1.2 48343 14348 3 1520.906598 507.9766 Polymerase delta-interacting protein 3 OS=Homo sapiens OX=9606 GN=POLDIP3 PE=1 SV=2 8.6 2653.3 - 1.45E+06 - - - -0.8462 - 2.536 0.544 - 299.7 1 2 0 -0.0013 14 0 0 0 1.76E+07 1.46E+07 - - - 7.0778 1 221125_WJC_METTL3_EV_vs_WT_F04.14349.14349.3 6.43E-09 15/52 R.LLHVAVSDVNDDVR[166.11].R "sp|Q99460|PSMD1_HUMAN,tr|A0A7I2V4X0|A0A7I2V4X0_HUMAN,tr|A0A7I2V2K8|A0A7I2V2K8_HUMAN,tr|A0A7I2YQY1|A0A7I2YQY1_HUMAN,tr|A0A7I2V523|A0A7I2V523_HUMAN,tr|A0A7I2V641|A0A7I2V641_HUMAN,tr|A0A7I2YQI9|A0A7I2YQI9_HUMAN,tr|A0A7I2V262|A0A7I2V262_HUMAN,tr|A0A087WW66|A0A087WW66_HUMAN,tr|A0A7P0MW50|A0A7P0MW50_HUMAN,tr|A0A7I2V5C8|A0A7I2V5C8_HUMAN" 11 1560.8135 0.61 48344 14349 3 1560.814447 521.2785 26S proteasome non-ATPase regulatory subunit 1 OS=Homo sapiens OX=9606 GN=PSMD1 PE=1 SV=2 4.41 2653.4 - 1.36E+06 - - - 0.5811 - 2.844 0.588 - 351.4 1 2 0 0.0009 14 0 0 0 9.19E+06 1.51E+07 - - - 7.8731 0.9996 221125_WJC_METTL3_EV_vs_WT_F04.14351.14351.3 0.0142 Nov-40 R.ER[166.11]PAAIPIEIK[136.11].S sp|Q9Y2H1|ST38L_HUMAN 1 1253.7462 3.74 48346 14351 3 1253.745621 418.9227 Serine\threonine-protein kinase 38-like OS=Homo sapiens OX=9606 GN=STK38L PE=1 SV=3 6.24 2653.6 - 743620 - - - -0.4953 - 1.898 0.331 - 204.5 1 2 0 -0.0006 11 0 0 0 1.81E+08 4.84E+07 - - - 4.0506 1 221125_WJC_METTL3_EV_vs_WT_F04.14353.14353.3 6.22E-06 17/44 R.LYEHYPAEFPC[160.03]R.L "sp|P42694|HELZ_HUMAN,tr|J3QS41|J3QS41_HUMAN" 2 1580.7082 3.34 48348 14353 3 1580.706904 527.91 Probable helicase with zinc finger domain OS=Homo sapiens OX=9606 GN=HELZ PE=1 SV=2 5.4 2653.8 - 555924 - - - -0.8193 - 2.641 0.498 - 417.6 1 2 0 -0.0013 12 0 0 0 1.39E+07 4.16E+06 - - - 6.7838 0.9999 221125_WJC_METTL3_EV_vs_WT_F04.14357.14357.2 0.000259 15/20 K.HFSGLEEAVYR[166.11].N "sp|P50990|TCPQ_HUMAN,tr|H7C4C8|H7C4C8_HUMAN" 2 1316.6389 0.34 48350 14357 2 1316.637655 659.3267 T-complex protein 1 subunit theta OS=Homo sapiens OX=9606 GN=CCT8 PE=1 SV=4 5.4 2654.4 - 1.02E+07 - - - -0.9228 - 3.081 0.491 - 625.1 1 2 0 -0.0012 11 0 0 0 1.07E+08 3.17E+08 - - - 5.7112 0.9999 221125_WJC_METTL3_EV_vs_WT_F04.14358.14358.2 0.00833 18-Dec K.SSEEIESAFR.A "sp|Q13813|SPTN1_HUMAN,tr|A0A0D9SF54|A0A0D9SF54_HUMAN,tr|A0A0D9SGF6|A0A0D9SGF6_HUMAN,tr|A0A0D9SFH4|A0A0D9SFH4_HUMAN" 4 1153.5251 1 48351 14358 2 1153.525024 577.7698 "Spectrin alpha chain, non-erythrocytic 1 OS=Homo sapiens OX=9606 GN=SPTAN1 PE=1 SV=3" 4.25 2654.4 - 2.40E+06 - - - -0.0936 - 2.48 0.454 - 796.8 1 2 0 -0.0001 10 0 0 0 2.62E+07 2.61E+07 - - - 4.9294 0.9995 221125_WJC_METTL3_EV_vs_WT_F04.14359.14359.3 0.00379 Dec-40 K.VKLEAEIATYR.R "sp|P05783|K1C18_HUMAN,tr|F8VZY9|F8VZY9_HUMAN" 2 1291.7136 2.12 48352 14359 3 1291.713263 431.5785 "Keratin, type I cytoskeletal 18 OS=Homo sapiens OX=9606 GN=KRT18 PE=1 SV=2" 6.11 2654.5 - 2.17E+06 - - - -0.2624 - 2.287 0.378 - 238.5 1 2 1 -0.0003 11 0 0 0 2.23E+07 1.05E+07 - - - 5.1043 0.9991 221125_WJC_METTL3_EV_vs_WT_F04.14360.14360.3 0.0142 Oct-44 K.LIPDSIGK[136.11]DIEK[136.11].A "sp|P61247|RS3A_HUMAN,tr|D6R9B6|D6R9B6_HUMAN,tr|H0Y9Y4|H0Y9Y4_HUMAN,tr|D6RB09|D6RB09_HUMAN,tr|D6RAT0|D6RAT0_HUMAN,tr|D6RG13|D6RG13_HUMAN" 6 1342.7679 1 48353 14360 3 1342.769806 448.5966 40S ribosomal protein S3a OS=Homo sapiens OX=9606 GN=RPS3A PE=1 SV=2 4.56 2654.6 - 1.71E+06 - - - 1.4329 - 2.074 0.39 - 106.1 1 2 1 0.0019 12 0 0 0 1.34E+08 1.34E+08 - - - 4.9096 0.999 221125_WJC_METTL3_EV_vs_WT_F04.14361.14361.3 0.00343 Nov-48 R.EGVVQGVASVAEK.T sp|Q16143|SYUB_HUMAN 1 1271.6721 1.42 48354 14361 3 1271.670735 424.898 Beta-synuclein OS=Homo sapiens OX=9606 GN=SNCB PE=1 SV=1 4.53 2654.7 - 1.12E+06 - - - -1.0978 - 2.003 0.259 - 203.5 1 2 0 -0.0014 13 0 0 0 2.65E+07 1.86E+07 - - - 3.3106 0.9999 221125_WJC_METTL3_EV_vs_WT_F04.14363.14363.3 1.36E-05 13/52 K.IITDVIGNPEEER[166.11]R[166.11].A "sp|Q92925|SMRD2_HUMAN,tr|B9EGA3|B9EGA3_HUMAN,tr|J3KMX2|J3KMX2_HUMAN,tr|J3QWB6|J3QWB6_HUMAN" 4 1659.8695 1.11 48356 14363 3 1659.866999 554.2971 SWI\SNF-related matrix-associated actin-dependent regulator of chromatin subfamily D member 2 OS=Homo sapiens OX=9606 GN=SMARCD2 PE=1 SV=3 4.41 2654.9 - 639017 - - - -1.5001 - 2.52 0.449 - 226.3 1 2 0 -0.0025 14 0 0 0 7.66E+06 6.90E+06 - - - 6.0015 0.9997 221125_WJC_METTL3_EV_vs_WT_F04.14364.14364.2 0.0127 18-Oct R.QDLTTLDVTK[136.11].L "sp|Q2VIR3|IF2GL_HUMAN,sp|P41091|IF2G_HUMAN,tr|H7BZU1|H7BZU1_HUMAN" 3 1140.6118 0.93 48357 14364 2 1140.611422 571.3132 Eukaryotic translation initiation factor 2 subunit 3B OS=Homo sapiens OX=9606 GN=EIF2S3B PE=2 SV=2 4.21 2655.1 - 580716 - - - -0.3042 - 2.306 0.314 - 320.7 1 2 0 -0.0003 10 0 0 0 8.71E+06 9.33E+06 - - - 3.6923 0.9998 221125_WJC_METTL3_EV_vs_WT_F04.14368.14368.3 0.000344 Dec-44 K.LIPDSIGKDIEK.A "sp|P61247|RS3A_HUMAN,tr|D6R9B6|D6R9B6_HUMAN,tr|H0Y9Y4|H0Y9Y4_HUMAN,tr|D6RB09|D6RB09_HUMAN,tr|D6RAT0|D6RAT0_HUMAN,tr|D6RG13|D6RG13_HUMAN" 6 1326.7395 1 48359 14368 3 1326.737666 443.2538 40S ribosomal protein S3a OS=Homo sapiens OX=9606 GN=RPS3A PE=1 SV=2 4.56 2655.6 - 3.71E+06 - - - -1.3688 - 2.158 0.488 - 173.7 1 2 1 -0.0018 12 0 0 0 1.35E+08 1.35E+08 - - - 6.1123 1 221125_WJC_METTL3_EV_vs_WT_F04.14369.14369.3 2.72E-05 16/52 R.YAPSEAGLHEMDIR[166.11].Y "sp|P21333|FLNA_HUMAN,tr|Q60FE5|Q60FE5_HUMAN,tr|H0Y5F3|H0Y5F3_HUMAN" 3 1597.7434 1.01 48360 14369 3 1597.743085 533.5884 Filamin-A OS=Homo sapiens OX=9606 GN=FLNA PE=1 SV=4 4.65 2655.7 - 1.39E+06 - - - -0.2047 - 2.822 0.58 - 258.1 1 2 0 -0.0003 14 0 0 0 2.18E+07 2.16E+07 - - - 7.7634 0.9995 221125_WJC_METTL3_EV_vs_WT_F04.14370.14370.2 0.00702 20-Oct R.ERPAAIPIEIK.S sp|Q9Y2H1|ST38L_HUMAN 1 1235.7238 3.99 48361 14370 2 1235.723872 618.8692 Serine\threonine-protein kinase 38-like OS=Homo sapiens OX=9606 GN=STK38L PE=1 SV=3 6.24 2655.9 - 1.65E+06 - - - 0.0809 - 2.185 0.257 - 422.1 1 2 0 0.0001 11 0 0 0 3.25E+07 8.13E+06 - - - 3.0536 1 221125_WJC_METTL3_EV_vs_WT_F04.14371.14371.3 0.00745 15/52 R.YAPSEAGLHEMDIR.Y "sp|P21333|FLNA_HUMAN,tr|Q60FE5|Q60FE5_HUMAN,tr|H0Y5F3|H0Y5F3_HUMAN" 3 1587.7351 1.01 48362 14371 3 1587.733941 530.2523 Filamin-A OS=Homo sapiens OX=9606 GN=FLNA PE=1 SV=4 4.65 2656 - 1.55E+06 - - - -0.7564 - 3.04 0.417 - 211.5 1 2 0 -0.0012 14 0 0 0 2.18E+07 2.16E+07 - - - 6.1436 0.9987 221125_WJC_METTL3_EV_vs_WT_F04.14375.14375.2 0.122 20-Nov R.ER[166.11]PAAIPIEIK[136.11].S sp|Q9Y2H1|ST38L_HUMAN 1 1253.7462 3.99 48366 14375 2 1253.743643 627.8804 Serine\threonine-protein kinase 38-like OS=Homo sapiens OX=9606 GN=STK38L PE=1 SV=3 6.24 2656.4 - 430343 - - - -2.073 - 2.096 0.253 - 421.9 1 2 0 -0.0026 11 0 0 0 3.25E+07 8.13E+06 - - - 2.9108 0.9999 221125_WJC_METTL3_EV_vs_WT_F04.14376.14376.3 0.000846 Sep-36 K.SHTFPELAYR.K sp|Q9NSD9|SYFB_HUMAN 1 1219.5986 0.48 48367 14376 3 1219.598689 407.5401 Phenylalanine--tRNA ligase beta subunit OS=Homo sapiens OX=9606 GN=FARSB PE=1 SV=3 6.47 2656.6 - 277308 - - - 0.0959 - 1.749 0.437 - 117.4 1 2 0 0.0001 10 0 0 0 4.23E+06 8.79E+06 - - - 5.0447 0.9995 221125_WJC_METTL3_EV_vs_WT_F04.14379.14379.2 2.01E-05 20-Nov R.EEAENTLQSFR.Q "sp|P08670|VIME_HUMAN,tr|B0YJC5|B0YJC5_HUMAN,tr|B0YJC4|B0YJC4_HUMAN" 3 1322.6103 1.7 48369 14379 2 1322.606128 662.3124 Vimentin OS=Homo sapiens OX=9606 GN=VIM PE=1 SV=4 4.25 2656.9 - 646917 - - - -3.1234 - 1.996 0.567 - 368.8 1 2 0 -0.0041 11 0 0 0 7.46E+06 4.39E+06 - - - 5.0973 0.9982 221125_WJC_METTL3_EV_vs_WT_F04.14381.14381.2 1.09E-05 22-Oct K.LIPDSIGKDIEK.A "sp|P61247|RS3A_HUMAN,tr|D6R9B6|D6R9B6_HUMAN,tr|H0Y9Y4|H0Y9Y4_HUMAN,tr|D6RB09|D6RB09_HUMAN,tr|D6RAT0|D6RAT0_HUMAN,tr|D6RG13|D6RG13_HUMAN" 6 1326.7395 1.13 48371 14381 2 1326.739589 664.377 40S ribosomal protein S3a OS=Homo sapiens OX=9606 GN=RPS3A PE=1 SV=2 4.56 2657.2 - 815159 - - - 0.0806 - 1.978 0.48 - 265.5 1 2 1 0.0001 12 0 0 0 2.09E+07 1.85E+07 - - - 4.3809 1 221125_WJC_METTL3_EV_vs_WT_F04.14382.14382.3 1.20E-08 Nov-40 K.YC[160.03]FPNYVGRPK.H "sp|P61163|ACTZ_HUMAN,sp|P42025|ACTY_HUMAN,tr|R4GMT0|R4GMT0_HUMAN,tr|A0A1B0GVS3|A0A1B0GVS3_HUMAN" 4 1399.6707 1.43 48372 14382 3 1399.672 467.5642 Alpha-centractin OS=Homo sapiens OX=9606 GN=ACTR1A PE=1 SV=1 9.2 2657.3 - 702500 - - - 0.9352 - 2.153 0.634 - 128.7 1 2 0 0.0013 11 0 0 0 1.07E+07 7.51E+06 - - - 7.7866 0.9993 221125_WJC_METTL3_EV_vs_WT_F04.14383.14383.3 0.00499 Nov-40 K.TRLEQEIATYR.R "sp|Q04695|K1C17_HUMAN,sp|P02533|K1C14_HUMAN,sp|P35900|K1C20_HUMAN,sp|P08779|K1C16_HUMAN,sp|P19012|K1C15_HUMAN,sp|P13646|K1C13_HUMAN,tr|A0A3B3IS58|A0A3B3IS58_HUMAN,tr|F5GWP8|F5GWP8_HUMAN,tr|K7ERE3|K7ERE3_HUMAN,tr|A8MT21|A8MT21_HUMAN" 10 1378.7205 2.58 48373 14383 3 1378.717611 460.5808 "Keratin, type I cytoskeletal 17 OS=Homo sapiens OX=9606 GN=KRT17 PE=1 SV=2" 5.81 2657.4 - 498848 - - - -2.0795 - 2.352 0.396 - 230.8 1 2 1 -0.0029 11 0 0 0 7.65E+06 2.97E+06 - - - 5.3839 0.9999 221125_WJC_METTL3_EV_vs_WT_F04.14384.14384.3 0.000607 13/60 K.IVYGHLDDPASQEIER.G "sp|Q99798|ACON_HUMAN,tr|A0A7I2V3U7|A0A7I2V3U7_HUMAN,tr|A0A7I2V3F1|A0A7I2V3F1_HUMAN,tr|A0A7I2V5T4|A0A7I2V5T4_HUMAN,tr|A2A274|A2A274_HUMAN,tr|A0A7I2V586|A0A7I2V586_HUMAN,tr|A0A7I2V614|A0A7I2V614_HUMAN,tr|A0A7I2V4I8|A0A7I2V4I8_HUMAN,tr|A0A7I2V5W7|A0A7I2V5W7_HUMAN,tr|A0A7I2V5A1|A0A7I2V5A1_HUMAN,tr|A0A7I2V3U0|A0A7I2V3U0_HUMAN,tr|A0A7I2V3C8|A0A7I2V3C8_HUMAN,tr|A0A7I2V538|A0A7I2V538_HUMAN,tr|A0A7I2V6A6|A0A7I2V6A6_HUMAN" 14 1840.8955 0.71 48374 14384 3 1840.897417 614.6391 "Aconitate hydratase, mitochondrial OS=Homo sapiens OX=9606 GN=ACO2 PE=1 SV=2" 4.31 2657.5 - 410400 - - - 1.0185 - 2.444 0.463 - 245.7 1 2 0 0.0019 16 0 0 0 6.28E+06 8.84E+06 - - - 5.9944 0.9995 221125_WJC_METTL3_EV_vs_WT_F04.14389.14389.3 0.00024 13/48 R.GGGHILPYDQPLR.A "sp|Q9H3G5|CPVL_HUMAN,tr|H7C218|H7C218_HUMAN,tr|H7C0X5|H7C0X5_HUMAN" 3 1421.7415 0.12 48377 14389 3 1421.739555 474.9211 Probable serine carboxypeptidase CPVL OS=Homo sapiens OX=9606 GN=CPVL PE=1 SV=2 6.74 2658.1 - 1.46E+06 - - - -1.4018 - 2.433 0.274 - 272.5 1 2 0 -0.002 13 0 0 0 2.32E+07 1.97E+08 - - - 4.005 0.9997 221125_WJC_METTL3_EV_vs_WT_F04.14391.14391.2 0.00121 20-Oct R.LLASTLVHSVK[136.11].K "sp|Q9NYF8|BCLF1_HUMAN,tr|E9PKI6|E9PKI6_HUMAN,tr|A0A1W2PQ43|A0A1W2PQ43_HUMAN,tr|E9PK91|E9PK91_HUMAN,tr|E9PJA7|E9PJA7_HUMAN,tr|E9PK09|E9PK09_HUMAN,tr|E9PQN2|E9PQN2_HUMAN" 7 1174.7165 2.19 48379 14391 2 1174.716292 588.3655 Bcl-2-associated transcription factor 1 OS=Homo sapiens OX=9606 GN=BCLAF1 PE=1 SV=2 8.76 2658.4 - 1.08E+06 - - - -0.1847 - 2.11 0.328 - 255.5 1 2 0 -0.0002 11 0 0 0 3.51E+07 1.60E+07 - - - 3.4835 0.9999 221125_WJC_METTL3_EV_vs_WT_F04.14392.14392.3 0.00111 Dec-48 K.VLISDSLDPC[160.03]C[160.03]R[166.11]K[136.11].L "sp|O43175|SERA_HUMAN,tr|A0A2C9F2M7|A0A2C9F2M7_HUMAN,tr|A0A286YFB2|A0A286YFB2_HUMAN,tr|A0A286YF34|A0A286YF34_HUMAN,tr|A0A286YFC8|A0A286YFC8_HUMAN,tr|A0A286YF22|A0A286YF22_HUMAN,tr|A0A286YFL2|A0A286YFL2_HUMAN,tr|A0A286YFA2|A0A286YFA2_HUMAN,tr|A0A286YFM8|A0A286YFM8_HUMAN,tr|A0A286YER3|A0A286YER3_HUMAN,tr|A0A286YFF3|A0A286YFF3_HUMAN,tr|A0A286YFK5|A0A286YFK5_HUMAN" 12 1579.7817 0.9 48380 14392 3 1579.781037 527.6012 D-3-phosphoglycerate dehydrogenase OS=Homo sapiens OX=9606 GN=PHGDH PE=1 SV=4 5.92 2658.5 - 632870 - - - -0.4317 - 2.214 0.377 - 168.3 1 2 0 -0.0007 13 0 0 0 8.44E+06 9.41E+06 - - - 4.8979 0.9999 221125_WJC_METTL3_EV_vs_WT_F04.14393.14393.2 2.83E-07 18-Oct R.YSGSYNDYLR[166.11].A sp|Q96PK6|RBM14_HUMAN 1 1246.5494 1.76 48381 14393 2 1246.54949 624.282 RNA-binding protein 14 OS=Homo sapiens OX=9606 GN=RBM14 PE=1 SV=2 5.83 2658.6 - 556016 - - - 0.0826 - 1.952 0.65 - 248.2 1 2 0 0.0001 10 0 0 0 1.01E+08 5.73E+07 - - - 5.7088 0.9989 221125_WJC_METTL3_EV_vs_WT_F04.14395.14395.3 0.000293 Oct-36 R.R[166.11]IDISPSTFR[166.11].K "sp|Q9Y2W1|TR150_HUMAN,tr|A0A3B3ITZ9|A0A3B3ITZ9_HUMAN" 2 1210.6573 2.46 48382 14395 3 1210.65622 404.5597 Thyroid hormone receptor-associated protein 3 OS=Homo sapiens OX=9606 GN=THRAP3 PE=1 SV=2 9.6 2658.8 - 6.65E+06 - - - -0.9012 - 2.119 0.225 - 200.2 1 2 0 -0.0011 10 0 0 0 3.20E+08 1.30E+08 - - - 3.2413 1 221125_WJC_METTL3_EV_vs_WT_F04.14397.14397.2 2.33E-09 15/26 K.ATAAFSNVGTAISK.K "sp|Q16890|TPD53_HUMAN,tr|E9PNK6|E9PNK6_HUMAN,tr|E9PPQ1|E9PPQ1_HUMAN,tr|J3KNE7|J3KNE7_HUMAN" 4 1336.6987 1.66 48383 14397 2 1336.697267 669.3566 Tumor protein D53 OS=Homo sapiens OX=9606 GN=TPD52L1 PE=1 SV=1 8.8 2659 - 1.88E+06 - - - -1.0571 - 2.987 0.599 - 743 1 2 0 -0.0014 14 0 0 0 4.95E+07 2.98E+07 - - - 6.2108 0.9958 221125_WJC_METTL3_EV_vs_WT_F04.14398.14398.2 0.00151 22-Oct K.LIPDSIGK[136.11]DIEK[136.11].A "sp|P61247|RS3A_HUMAN,tr|D6R9B6|D6R9B6_HUMAN,tr|H0Y9Y4|H0Y9Y4_HUMAN,tr|D6RB09|D6RB09_HUMAN,tr|D6RAT0|D6RAT0_HUMAN,tr|D6RG13|D6RG13_HUMAN" 6 1342.7679 1.13 48384 14398 2 1342.765841 672.3912 40S ribosomal protein S3a OS=Homo sapiens OX=9606 GN=RPS3A PE=1 SV=2 4.56 2659.1 - 1.31E+06 - - - -1.52 - 1.565 0.493 - 286.8 1 2 1 -0.002 12 0 0 0 2.09E+07 1.85E+07 - - - 3.8601 0.9999 221125_WJC_METTL3_EV_vs_WT_F04.14399.14399.3 0.000128 16/48 R.EGVVQGVASVAEK[136.11].T sp|Q16143|SYUB_HUMAN 1 1279.6863 1.42 48385 14399 3 1279.685102 427.5694 Beta-synuclein OS=Homo sapiens OX=9606 GN=SNCB PE=1 SV=1 4.53 2659.2 - 1.37E+06 - - - -0.9604 - 2.488 0.377 - 467.9 1 2 0 -0.0012 13 0 0 0 2.67E+07 1.88E+07 - - - 5.2141 1 221125_WJC_METTL3_EV_vs_WT_F04.14401.14401.3 8.96E-07 16/44 R.LLGVFEQNQDR[166.11]K[136.11].H sp|Q96G61|NUD11_HUMAN 1 1463.7851 0.62 48387 14401 3 1463.783278 488.9357 Diphosphoinositol polyphosphate phosphohydrolase 3-beta OS=Homo sapiens OX=9606 GN=NUDT11 PE=1 SV=1 6.07 2659.4 - 1.15E+06 - - - -1.2768 - 2.853 0.468 - 374.9 1 2 0 -0.0019 12 0 0 0 1.29E+07 2.09E+07 - - - 6.6631 0.9892 221125_WJC_METTL3_EV_vs_WT_F04.14402.14402.3 0.0723 Sep-44 K.VTVLFAGQHISK.S "sp|O75369|FLNB_HUMAN,tr|E7EN95|E7EN95_HUMAN,tr|A0A804HK76|A0A804HK76_HUMAN,tr|A0A804HJC2|A0A804HJC2_HUMAN,tr|A0A804HL72|A0A804HL72_HUMAN" 5 1298.7347 0.83 48388 14402 3 1298.73299 433.9188 Filamin-B OS=Homo sapiens OX=9606 GN=FLNB PE=1 SV=2 8.73 2659.5 - 899460 - - - -1.2951 - 1.67 0.169 - 85.1 1 2 0 -0.0017 12 0 0 0 1.09E+07 1.31E+07 - - - 1.8452 1 221125_WJC_METTL3_EV_vs_WT_F04.14404.14404.2 2.63E-07 14/22 H.ESETTTSLVLER[166.11].S "sp|Q04837|SSBP_HUMAN,tr|C9J8J0|C9J8J0_HUMAN,tr|C9K0U8|C9K0U8_HUMAN,tr|A0A0G2JLD8|A0A0G2JLD8_HUMAN,tr|E7EUY5|E7EUY5_HUMAN" 5 1373.6914 1.32 48390 14404 2 1373.690169 687.853 "Single-stranded DNA-binding protein, mitochondrial OS=Homo sapiens OX=9606 GN=SSBP1 PE=1 SV=1" 4.25 2659.8 - 768071 - - - -0.867 - 2.835 0.581 - 1001 1 1 0 -0.0012 12 0 0 0 1.82E+08 1.38E+08 - - - 6.0737 0.9995 221125_WJC_METTL3_EV_vs_WT_F04.14405.14405.2 5.63E-07 26-Dec K.ELSTTLNADEAVTR.G "sp|P34932|HSP74_HUMAN,tr|A0A087WTS8|A0A087WTS8_HUMAN,tr|A0A087WYC1|A0A087WYC1_HUMAN" 3 1518.7526 0.09 48391 14405 2 1518.757428 760.3836 Heat shock 70 kDa protein 4 OS=Homo sapiens OX=9606 GN=HSPA4 PE=1 SV=4 4.14 2659.9 - 635304 - - - 3.2013 - 2.568 0.563 - 310.7 1 2 0 0.0049 14 0 0 0 8.89E+06 1.04E+08 - - - 5.5645 0.9999 221125_WJC_METTL3_EV_vs_WT_F04.14408.14408.2 4.47E-06 18-Sep R.YSGSYNDYLR.A sp|Q96PK6|RBM14_HUMAN 1 1236.5411 1.76 48392 14408 2 1236.54081 619.2778 RNA-binding protein 14 OS=Homo sapiens OX=9606 GN=RBM14 PE=1 SV=2 5.83 2660.3 - 3.47E+06 - - - -0.2483 - 1.692 0.591 - 202.3 1 2 0 -0.0003 10 0 0 0 1.01E+08 5.73E+07 - - - 4.874 0.9999 221125_WJC_METTL3_EV_vs_WT_F04.14409.14409.2 8.40E-07 26-Nov K.ATAAFSNVGTAISK[136.11].K "sp|Q16890|TPD53_HUMAN,tr|E9PNK6|E9PNK6_HUMAN,tr|E9PPQ1|E9PPQ1_HUMAN,tr|J3KNE7|J3KNE7_HUMAN" 4 1344.7129 1.66 48393 14409 2 1344.71091 673.3637 Tumor protein D53 OS=Homo sapiens OX=9606 GN=TPD52L1 PE=1 SV=1 8.8 2660.4 - 1.43E+06 - - - -1.465 - 2.524 0.569 - 346.7 1 2 0 -0.002 14 0 0 0 4.95E+07 2.98E+07 - - - 5.5664 1 221125_WJC_METTL3_EV_vs_WT_F04.14410.14410.2 0.0041 13/18 R.TDDLC[160.03]LDVSK.L sp|Q10472|GALT1_HUMAN 1 1164.5333 1.82 48394 14410 2 1164.532403 583.2739 Polypeptide N-acetylgalactosaminyltransferase 1 OS=Homo sapiens OX=9606 GN=GALNT1 PE=1 SV=1 3.93 2660.5 - 1.57E+06 - - - -0.7308 - 2.682 0.535 - 881 1 2 0 -0.0009 10 0 0 0 3.41E+07 1.88E+07 - - - 5.746 0.9999 221125_WJC_METTL3_EV_vs_WT_F04.14411.14411.2 0.0112 13/18 R.TDDLC[160.03]LDVSK[136.11].L sp|Q10472|GALT1_HUMAN 1 1172.5475 1.71 48395 14411 2 1172.548149 587.281 Polypeptide N-acetylgalactosaminyltransferase 1 OS=Homo sapiens OX=9606 GN=GALNT1 PE=1 SV=1 3.93 2660.6 - 959741 - - - 0.5927 - 2.561 0.481 - 828.4 1 2 0 0.0007 10 0 0 0 3.19E+07 1.86E+07 - - - 5.2184 1 221125_WJC_METTL3_EV_vs_WT_F04.14413.14413.2 0.000794 15/18 K.HYEVEILDAK[136.11].T "sp|Q9NZ01|TECR_HUMAN,tr|M0R3C3|M0R3C3_HUMAN" 2 1223.6278 1 48397 14413 2 1223.624743 612.8212 Very-long-chain enoyl-CoA reductase OS=Homo sapiens OX=9606 GN=TECR PE=1 SV=1 4.65 2660.9 - 850109 - - - -2.4599 - 3.077 0.528 - 776 1 2 0 -0.003 10 0 0 0 1.63E+07 1.63E+07 - - - 6.0772 0.9718 221125_WJC_METTL3_EV_vs_WT_F04.14414.14414.2 9.53E-05 22-Nov R.YSNVIQPSSFSK.S "sp|O15504|NUP42_HUMAN,tr|B4DT96|B4DT96_HUMAN,tr|C9JYA1|C9JYA1_HUMAN" 3 1355.6721 0.11 48398 14414 2 1356.672262 678.8433 Nucleoporin NUP42 OS=Homo sapiens OX=9606 GN=NUP42 PE=1 SV=1 8.59 2661 - 416342 - - - 737.7381 - 1.83 0.471 - 368.8 1 2 0 1.0001 12 0 0 0 1.34E+07 1.22E+08 - - - 3.7958 0.9999 221125_WJC_METTL3_EV_vs_WT_F04.14419.14419.3 1.16E-05 13/44 K.VNGRPLEMIEPR.T "sp|P62249|RS16_HUMAN,tr|M0R3H0|M0R3H0_HUMAN,tr|M0R1M5|M0R1M5_HUMAN,tr|Q6IPX4|Q6IPX4_HUMAN" 4 1409.7449 0.82 48401 14419 3 1409.747058 470.9222 40S ribosomal protein S16 OS=Homo sapiens OX=9606 GN=RPS16 PE=1 SV=2 6.11 2661.6 - 2.95E+06 - - - 1.5173 - 2.523 0.431 - 223.4 1 2 0 0.0021 12 0 0 0 1.46E+08 1.79E+08 - - - 5.9098 0.9918 221125_WJC_METTL3_EV_vs_WT_F04.14421.14421.3 0.198 Oct-36 K.SEGFHDILPK.S sp|Q8IWC1|MA7D3_HUMAN 1 1141.5768 1.23 48403 14421 3 1141.575844 381.5329 MAP7 domain-containing protein 3 OS=Homo sapiens OX=9606 GN=MAP7D3 PE=1 SV=2 5.3 2661.8 - 961211 - - - -0.8147 - 1.492 0.199 - 131.6 1 2 0 -0.0009 10 0 0 0 2.12E+07 1.73E+07 - - - 1.9269 0.9996 221125_WJC_METTL3_EV_vs_WT_F04.14422.14422.3 0.00291 Dec-44 K.GGFLPPEEIKER.F sp|Q9H0D6|XRN2_HUMAN 1 1370.7194 0.83 48404 14422 3 1370.718098 457.9137 5'-3' exoribonuclease 2 OS=Homo sapiens OX=9606 GN=XRN2 PE=1 SV=1 4.79 2661.9 - 840461 - - - -0.9608 - 2.094 0.415 - 182.1 1 2 1 -0.0013 12 0 0 0 1.32E+07 1.59E+07 - - - 5.2151 1 221125_WJC_METTL3_EV_vs_WT_F04.14426.14426.2 0.000479 26-Dec R.VPVATYTNSSQPFR[166.11].L "sp|P49005|DPOD2_HUMAN,tr|A0A087WWF6|A0A087WWF6_HUMAN,tr|C9J8Z7|C9J8Z7_HUMAN,tr|F8W8R3|F8W8R3_HUMAN,tr|C9JHC7|C9JHC7_HUMAN,tr|C9IZD2|C9IZD2_HUMAN,tr|C9JLE1|C9JLE1_HUMAN" 7 1575.7921 0.98 48408 14426 2 1575.792461 788.9033 DNA polymerase delta subunit 2 OS=Homo sapiens OX=9606 GN=POLD2 PE=1 SV=1 8.72 2662.4 - 262638 - - - 0.2437 - 2.588 0.625 - 437.6 1 2 0 0.0004 14 0 0 0 3.75E+06 3.83E+06 - - - 6.0433 0.9996 221125_WJC_METTL3_EV_vs_WT_F04.14432.14432.2 1.08E-05 13/20 K.TPVPSDIDISR.S "sp|P11586|C1TC_HUMAN,tr|F5H2F4|F5H2F4_HUMAN,tr|V9GZ78|V9GZ78_HUMAN,tr|V9GYY3|V9GYY3_HUMAN,tr|A0A494C1T2|A0A494C1T2_HUMAN" 5 1198.6194 2.12 48412 14432 2 1198.619778 600.317 "C-1-tetrahydrofolate synthase, cytoplasmic OS=Homo sapiens OX=9606 GN=MTHFD1 PE=1 SV=4" 4.21 2663.2 - 1.42E+06 - - - 0.3429 - 2.183 0.309 - 598.8 1 2 0 0.0004 11 0 0 0 1.88E+07 8.86E+06 - - - 3.4351 0.9998 221125_WJC_METTL3_EV_vs_WT_F04.14434.14434.2 0.000457 16-Oct K.EYQELMNVK.L "sp|P48668|K2C6C_HUMAN,sp|P05787|K2C8_HUMAN,sp|P04259|K2C6B_HUMAN,sp|P02538|K2C6A_HUMAN,tr|Q8IWY7|Q8IWY7_HUMAN" 5 1152.5485 40.77 48414 14434 2 1152.548184 577.2815 "Keratin, type II cytoskeletal 6C OS=Homo sapiens OX=9606 GN=KRT6C PE=1 SV=3" 4.53 2663.4 - 918017 - - - -0.2829 - 1.651 0.453 - 439.5 1 2 0 -0.0003 9 0 0 0 2.89E+07 7.09E+05 - - - 3.8373 0.9999 221125_WJC_METTL3_EV_vs_WT_F04.14435.14435.2 0.000117 18-Dec K.HYEVEILDAK.T "sp|Q9NZ01|TECR_HUMAN,tr|M0R3C3|M0R3C3_HUMAN" 2 1215.6136 0.99 48415 14435 2 1215.613375 608.8141 Very-long-chain enoyl-CoA reductase OS=Homo sapiens OX=9606 GN=TECR PE=1 SV=1 4.65 2663.5 - 892368 - - - -0.1464 - 2.615 0.484 - 320.8 1 2 0 -0.0002 10 0 0 0 1.62E+07 1.63E+07 - - - 5.2989 0.9999 221125_WJC_METTL3_EV_vs_WT_F04.14436.14436.3 3.50E-05 Nov-40 R.FDDKPDYSYLR.Q "sp|P48730|KC1D_HUMAN,sp|P49674|KC1E_HUMAN,tr|B0QY34|B0QY34_HUMAN,tr|H7BYT1|H7BYT1_HUMAN,tr|A0A669KBC0|A0A669KBC0_HUMAN,tr|H0Y645|H0Y645_HUMAN,tr|B0QY35|B0QY35_HUMAN" 7 1417.6514 1.65 48416 14436 3 1417.649156 473.5577 Casein kinase I isoform delta OS=Homo sapiens OX=9606 GN=CSNK1D PE=1 SV=2 4.43 2663.6 - 680247 - - - -1.5794 - 2.065 0.473 - 112.8 1 2 0 -0.0022 11 0 0 0 1.29E+07 7.82E+06 - - - 5.8728 0.9997 221125_WJC_METTL3_EV_vs_WT_F04.14437.14437.3 0.0098 Dec-40 K.IEVEK[136.11]PFAIAK[136.11].E "sp|P23284|PPIB_HUMAN,tr|A0A7P0Z497|A0A7P0Z497_HUMAN,tr|A0A7P0TB45|A0A7P0TB45_HUMAN" 3 1259.746 0.41 48417 14437 3 1259.746243 420.9226 Peptidyl-prolyl cis-trans isomerase B OS=Homo sapiens OX=9606 GN=PPIB PE=1 SV=2 6.14 2663.7 - 671646 - - - 0.1738 - 2.027 0.328 - 175.3 1 2 0 0.0002 11 0 0 0 6.75E+06 1.66E+07 - - - 4.204 0.9999 221125_WJC_METTL3_EV_vs_WT_F04.14438.14438.2 0.0359 18-Dec R.DEDVFVC[160.03]ESR.Y "sp|Q86U86|PB1_HUMAN,tr|H0Y5B5|H0Y5B5_HUMAN,tr|E7EVG2|E7EVG2_HUMAN" 3 1254.5187 1.57 48418 14438 2 1254.517555 628.2666 Protein polybromo-1 OS=Homo sapiens OX=9606 GN=PBRM1 PE=1 SV=1 3.92 2663.8 - 612971 - - - -0.8864 - 2.441 0.517 - 755.7 1 2 0 -0.0011 10 0 0 0 1.17E+07 7.46E+06 - - - 5.3502 1 221125_WJC_METTL3_EV_vs_WT_F04.14439.14439.2 5.03E-05 16/32 R.YFATVGGSASETNIEEK.V sp|Q9ULV0|MYO5B_HUMAN 1 1801.837 7.75 48419 14439 2 1801.833609 901.9258 Unconventional myosin-Vb OS=Homo sapiens OX=9606 GN=MYO5B PE=1 SV=3 4.25 2663.9 - 320999 - - - -1.8953 - 2.78 0.693 - 670.1 1 2 0 -0.0034 17 0 0 0 3.41E+06 4.40E+05 - - - 6.6722 0.9929 221125_WJC_METTL3_EV_vs_WT_F04.14441.14441.3 0.278 Jul-56 K.KIFVGGLNPEATEEK.L "tr|D6R9P3|D6R9P3_HUMAN,tr|D6RD18|D6RD18_HUMAN,tr|D6RBZ0|D6RBZ0_HUMAN" 3 1630.8566 1.32 48421 14441 3 1630.857796 544.6262 Heterogeneous nuclear ribonucleoprotein A\B OS=Homo sapiens OX=9606 GN=HNRNPAB PE=1 SV=1 4.79 2664.2 - 219159 - - - 0.7107 - 1.431 0.228 - 57.7 1 2 0 0.0012 15 0 0 0 2.95E+06 2.24E+06 - - - 2.0168 1 221125_WJC_METTL3_EV_vs_WT_F04.14443.14443.2 1.85E-07 22-Nov K.TEELEEESFPER.S "sp|Q9Y2W1|TR150_HUMAN,tr|A0A3B3ITZ9|A0A3B3ITZ9_HUMAN" 2 1493.6522 2.83 48422 14443 2 1493.652438 747.8334 Thyroid hormone receptor-associated protein 3 OS=Homo sapiens OX=9606 GN=THRAP3 PE=1 SV=2 3.9 2664.4 - 7.33E+07 - - - 0.1707 - 2.55 0.665 - 517.1 1 2 0 0.0003 12 0 0 0 2.80E+09 9.87E+08 - - - 6.4156 1 221125_WJC_METTL3_EV_vs_WT_F04.14444.14444.2 2.14E-09 14/22 H.ESETTTSLVLER.S "sp|Q04837|SSBP_HUMAN,tr|C9J8J0|C9J8J0_HUMAN,tr|C9K0U8|C9K0U8_HUMAN,tr|A0A0G2JLD8|A0A0G2JLD8_HUMAN,tr|E7EUY5|E7EUY5_HUMAN" 5 1363.6831 1.32 48423 14444 2 1363.683593 682.8488 "Single-stranded DNA-binding protein, mitochondrial OS=Homo sapiens OX=9606 GN=SSBP1 PE=1 SV=1" 4.25 2664.5 - 1.25E+07 - - - 0.3689 - 2.821 0.606 - 997.2 1 1 0 0.0005 12 0 0 0 1.82E+08 1.38E+08 - - - 6.2455 0.9988 221125_WJC_METTL3_EV_vs_WT_F04.14446.14446.3 0.000895 Sep-48 K.FISGHTSELGDFR[166.11].F "sp|Q13724|MOGS_HUMAN,tr|A0A3B3IS52|A0A3B3IS52_HUMAN,tr|A0A3B3IRK6|A0A3B3IRK6_HUMAN,tr|C9JDQ1|C9JDQ1_HUMAN,tr|A0A3B3ITC1|A0A3B3ITC1_HUMAN" 5 1474.708 0.82 48425 14446 3 1474.706226 492.5766 Mannosyl-oligosaccharide glucosidase OS=Homo sapiens OX=9606 GN=MOGS PE=1 SV=5 5.32 2664.6 - 1.40E+06 - - - -1.2118 - 1.709 0.293 - 63 1 2 0 -0.0018 13 0 0 0 2.08E+07 2.54E+07 - - - 3.2592 0.7668 221125_WJC_METTL3_EV_vs_WT_F04.14447.14447.3 0.165 Sep-44 H.ESETTTSLVLER.S "sp|Q04837|SSBP_HUMAN,tr|C9J8J0|C9J8J0_HUMAN,tr|C9K0U8|C9K0U8_HUMAN,tr|A0A0G2JLD8|A0A0G2JLD8_HUMAN,tr|E7EUY5|E7EUY5_HUMAN" 5 1363.6831 1.2 48426 14447 3 1363.682255 455.5683 "Single-stranded DNA-binding protein, mitochondrial OS=Homo sapiens OX=9606 GN=SSBP1 PE=1 SV=1" 4.25 2664.7 - 902510 - - - -0.6123 - 1.764 0.222 - 138.1 1 1 0 -0.0008 12 0 0 0 1.14E+07 9.47E+06 - - - 2.5881 0.9984 221125_WJC_METTL3_EV_vs_WT_F04.14448.14448.2 0.00939 18-Nov K.TIDDLEDK[136.11]LK[136.11].C "tr|A0A087WWU8|A0A087WWU8_HUMAN,tr|J3KN67|J3KN67_HUMAN" 2 1204.6522 10.24 48427 14448 2 1204.65157 603.3334 Tropomyosin alpha-3 chain OS=Homo sapiens OX=9606 GN=TPM3 PE=1 SV=1 4.23 2664.8 - 798417 - - - -0.5097 - 2.165 0.46 - 248.5 1 2 1 -0.0006 10 0 0 0 8.02E+07 7.83E+06 - - - 4.5944 0.9991 221125_WJC_METTL3_EV_vs_WT_F04.14449.14449.3 0.00125 15/48 R.DMLLANK[136.11]VPAAAR[166.11].A "sp|Q8NHW5|RLA0L_HUMAN,sp|P05388|RLA0_HUMAN,tr|G3V210|G3V210_HUMAN,tr|F8VU65|F8VU65_HUMAN,tr|F8VWV4|F8VWV4_HUMAN,tr|F8VWS0|F8VWS0_HUMAN,tr|F8VW21|F8VW21_HUMAN,tr|F8VRK7|F8VRK7_HUMAN,tr|F8VQY6|F8VQY6_HUMAN,tr|F8VPE8|F8VPE8_HUMAN" 10 1386.7772 1.23 48428 14449 3 1386.776481 463.2664 60S acidic ribosomal protein P0-like OS=Homo sapiens OX=9606 GN=RPLP0P6 PE=5 SV=1 8.75 2664.9 - 692372 - - - -0.5365 - 2.095 0.366 - 262.1 1 2 1 -0.0007 13 0 0 0 2.23E+07 1.81E+07 - - - 4.6255 1 221125_WJC_METTL3_EV_vs_WT_F04.14450.14450.2 4.99E-06 20-Dec K.EEYQLVQVEQK[136.11].A sp|Q9NR30|DDX21_HUMAN 1 1399.7075 0.76 48429 14450 2 1399.706069 700.861 Nucleolar RNA helicase 2 OS=Homo sapiens OX=9606 GN=DDX21 PE=1 SV=5 4.25 2665.1 - 559553 - - - -0.9938 - 2.318 0.624 - 400.6 1 2 0 -0.0014 11 0 0 0 5.39E+06 7.05E+06 - - - 5.9237 0.9999 221125_WJC_METTL3_EV_vs_WT_F04.14451.14451.2 7.42E-06 24-Dec K.SNIEETTISSQK[136.11]I.- sp|Q16352|AINX_HUMAN 1 1456.7501 1.71 48430 14451 2 1456.750172 729.3823 Alpha-internexin OS=Homo sapiens OX=9606 GN=INA PE=1 SV=2 4.53 2665.2 - 510641 - - - 0.0817 - 2.76 0.52 - 343.4 1 2 0 0.0001 13 0 0 0 1.18E+07 6.90E+06 - - - 5.4873 1 221125_WJC_METTL3_EV_vs_WT_F04.14455.14455.2 4.78E-08 13/28 R.VASYSGTVTQATFTR.T "sp|Q5VWN6|TASO2_HUMAN,tr|A0A2R8YH03|A0A2R8YH03_HUMAN" 2 1587.7893 1.39 48434 14455 2 1587.786451 794.9019 Protein TASOR 2 OS=Homo sapiens OX=9606 GN=TASOR2 PE=1 SV=1 8.72 2665.7 - 225076 - - - -1.7855 - 2.871 0.619 - 658.9 1 2 0 -0.0028 15 0 0 0 2.67E+06 1.92E+06 - - - 6.205 1 221125_WJC_METTL3_EV_vs_WT_F04.14458.14458.2 2.75E-08 22-Dec K.TEELEEESFPER[166.11].S "sp|Q9Y2W1|TR150_HUMAN,tr|A0A3B3ITZ9|A0A3B3ITZ9_HUMAN" 2 1503.6605 2.83 48435 14458 2 1503.660243 752.8375 Thyroid hormone receptor-associated protein 3 OS=Homo sapiens OX=9606 GN=THRAP3 PE=1 SV=2 3.9 2666.1 - 2.22E+07 - - - -0.1397 - 2.565 0.647 - 601.2 1 2 0 -0.0002 12 0 0 0 2.80E+09 9.87E+08 - - - 6.2981 0.9996 221125_WJC_METTL3_EV_vs_WT_F04.14459.14459.2 0.191 18-Nov R.R[166.11]IDISPSTFR[166.11].K "sp|Q9Y2W1|TR150_HUMAN,tr|A0A3B3ITZ9|A0A3B3ITZ9_HUMAN" 2 1210.6573 3.01 48436 14459 2 1210.657542 606.3359 Thyroid hormone receptor-associated protein 3 OS=Homo sapiens OX=9606 GN=THRAP3 PE=1 SV=2 9.6 2666.2 - 2.63E+06 - - - 0.1908 - 2.226 0.263 - 206 1 2 0 0.0002 10 0 0 0 1.41E+08 4.68E+07 - - - 3.2171 0.9999 221125_WJC_METTL3_EV_vs_WT_F04.14460.14460.3 0.000181 Nov-40 K.YDVQHLQTALR.N "sp|O14653|GOSR2_HUMAN,tr|I3NI02|I3NI02_HUMAN,tr|E7EQ34|E7EQ34_HUMAN,tr|A0A1W2PPP5|A0A1W2PPP5_HUMAN,tr|A0A1W2PPG5|A0A1W2PPG5_HUMAN,tr|I3L0K1|I3L0K1_HUMAN,tr|A0A1W2PR23|A0A1W2PR23_HUMAN,tr|A0A1W2PRC2|A0A1W2PRC2_HUMAN,tr|A0A1W2PQP2|A0A1W2PQP2_HUMAN,tr|A0A1W2PRP7|A0A1W2PRP7_HUMAN,tr|A0A1W2PR02|A0A1W2PR02_HUMAN,tr|A0A1X7SBU8|A0A1X7SBU8_HUMAN,tr|A0A1W2PS81|A0A1W2PS81_HUMAN,tr|I3L4Z6|I3L4Z6_HUMAN,tr|A0A1W2PQ77|A0A1W2PQ77_HUMAN,tr|A0A1W2PPJ0|A0A1W2PPJ0_HUMAN,tr|A0A1W2PRD0|A0A1W2PRD0_HUMAN,tr|A0A1W2PPG1|A0A1W2PPG1_HUMAN,tr|A0A1W2PRV0|A0A1W2PRV0_HUMAN,tr|A0A1W2PQ06|A0A1W2PQ06_HUMAN,tr|A0A1W2PPW8|A0A1W2PPW8_HUMAN,tr|A0A1W2PNV3|A0A1W2PNV3_HUMAN,tr|A0A1W2PQ38|A0A1W2PQ38_HUMAN,tr|A0A1W2PQM3|A0A1W2PQM3_HUMAN,tr|A0A1W2PRE6|A0A1W2PRE6_HUMAN,tr|A0A1W2PQE0|A0A1W2PQE0_HUMAN,tr|I3L1K7|I3L1K7_HUMAN,tr|A0A1W2PS12|A0A1W2PS12_HUMAN,tr|A0A1W2PRL0|A0A1W2PRL0_HUMAN" 29 1342.6993 1.16 48437 14460 3 1342.699896 448.5737 Golgi SNAP receptor complex member 2 OS=Homo sapiens OX=9606 GN=GOSR2 PE=1 SV=2 6.74 2666.2 - 2.64E+06 - - - 0.4074 - 1.9 0.442 - 132.7 1 2 0 0.0005 11 0 0 0 1.59E+07 1.37E+07 - - - 5.2911 0.9999 221125_WJC_METTL3_EV_vs_WT_F04.14462.14462.3 0.000704 Nov-48 K.FISGHTSELGDFR.F "sp|Q13724|MOGS_HUMAN,tr|A0A3B3IS52|A0A3B3IS52_HUMAN,tr|A0A3B3IRK6|A0A3B3IRK6_HUMAN,tr|C9JDQ1|C9JDQ1_HUMAN,tr|A0A3B3ITC1|A0A3B3ITC1_HUMAN" 5 1464.6997 0.82 48439 14462 3 1464.697789 489.2405 Mannosyl-oligosaccharide glucosidase OS=Homo sapiens OX=9606 GN=MOGS PE=1 SV=5 5.32 2666.3 - 1.58E+06 - - - -1.3341 - 2.122 0.478 - 82.1 1 2 0 -0.002 13 0 0 0 2.09E+07 2.54E+07 - - - 5.9085 0.9993 221125_WJC_METTL3_EV_vs_WT_F04.14463.14463.2 0.0162 18-Aug K.EDITQEFPGK[136.11].G "sp|P78344|IF4G2_HUMAN,tr|H0Y3P2|H0Y3P2_HUMAN,tr|H0YE22|H0YE22_HUMAN,tr|D3DQV9|D3DQV9_HUMAN" 4 1170.5648 2.38 48440 14463 2 1170.565634 586.2897 Eukaryotic translation initiation factor 4 gamma 2 OS=Homo sapiens OX=9606 GN=EIF4G2 PE=1 SV=1 4.14 2666.4 - 1.35E+06 - - - 0.6962 - 1.757 0.303 - 203.6 1 2 0 0.0008 10 0 0 0 5.31E+07 2.23E+07 - - - 2.8519 0.9826 221125_WJC_METTL3_EV_vs_WT_F04.14464.14464.2 0.00522 18-Dec L.NLQIDPSIQR.V "sp|P13647|K2C5_HUMAN,tr|F8W0C6|F8W0C6_HUMAN,tr|F8VU69|F8VU69_HUMAN" 3 1182.6357 4.47 48441 14464 2 1182.634663 592.3251 "Keratin, type II cytoskeletal 5 OS=Homo sapiens OX=9606 GN=KRT5 PE=1 SV=3" 5.84 2666.5 - 1.29E+06 - - - -0.865 - 2.061 0.364 - 446.6 1 1 0 -0.001 10 0 0 0 1.14E+08 2.55E+07 - - - 3.7478 0.9998 221125_WJC_METTL3_EV_vs_WT_F04.14465.14465.3 0.00092 Dec-48 R.QIGVEHVVVYVNK.A sp|P49411|EFTU_HUMAN 1 1482.8195 1.44 48442 14465 3 1482.81714 495.2804 "Elongation factor Tu, mitochondrial OS=Homo sapiens OX=9606 GN=TUFM PE=1 SV=2" 6.75 2666.6 - 999721 - - - -1.5673 - 2.008 0.399 - 189.8 1 2 0 -0.0023 13 0 0 0 1.97E+08 1.37E+08 - - - 4.878 0.9897 221125_WJC_METTL3_EV_vs_WT_F04.14468.14468.3 0.000108 14/48 A.QIHDLVLVGGSTR[166.11].L "sp|P0DMV8|HS71A_HUMAN,sp|P11142|HSP7C_HUMAN,sp|P0DMV9|HS71B_HUMAN,tr|E9PNE6|E9PNE6_HUMAN,tr|A8K7Q2|A8K7Q2_HUMAN,tr|E9PKE3|E9PKE3_HUMAN,tr|E9PN89|E9PN89_HUMAN,tr|V9GZ37|V9GZ37_HUMAN,tr|A0A0G2JIW1|A0A0G2JIW1_HUMAN" 9 1403.776 0.47 48445 14468 3 1403.77504 468.9326 Heat shock 70 kDa protein 1A OS=Homo sapiens OX=9606 GN=HSPA1A PE=1 SV=1 6.74 2667 - 750233 - - - -0.7074 - 2.55 0.37 - 258.7 1 1 0 -0.001 13 0 0 0 3.36E+06 7.21E+06 - - - 5.2029 1 221125_WJC_METTL3_EV_vs_WT_F04.14469.14469.2 4.14E-06 14/26 K.PSSSPVIFAGGQDR[166.11].Y "sp|Q15366|PCBP2_HUMAN,tr|H3BSS4|H3BSS4_HUMAN" 2 1426.708 1.39 48446 14469 2 1426.706949 714.3613 Poly(rC)-binding protein 2 OS=Homo sapiens OX=9606 GN=PCBP2 PE=1 SV=1 6.27 2667.1 - 594272 - - - -0.7458 - 3.299 0.562 - 636.9 1 1 0 -0.0011 14 0 0 0 8.35E+06 6.01E+06 - - - 6.1869 0.9796 221125_WJC_METTL3_EV_vs_WT_F04.14470.14470.3 0.127 Nov-36 K.MLEILEQQK[136.11]K[136.11].V "sp|P11172|UMPS_HUMAN,tr|E9PFD2|E9PFD2_HUMAN" 2 1274.7239 0.74 48447 14470 3 1274.726065 425.9152 Uridine 5'-monophosphate synthase OS=Homo sapiens OX=9606 GN=UMPS PE=1 SV=1 5.9 2667.2 - 543811 - - - 1.6913 - 1.711 0.139 - 155.5 1 2 0 0.0022 10 0 0 0 2.53E+06 3.44E+06 - - - 1.6576 0.9995 221125_WJC_METTL3_EV_vs_WT_F04.14474.14474.2 0.000555 26-Jun R.ELEDVTESAESMNR[166.11].E "sp|Q7Z406|MYH14_HUMAN,tr|A1L2Z2|A1L2Z2_HUMAN" 2 1618.702 -1 48451 14474 2 1618.700386 810.3583 Myosin-14 OS=Homo sapiens OX=9606 GN=MYH14 PE=1 SV=2 3.91 2667.8 - 245047 - - - -0.9977 - 1.439 0.43 - 75.1 1 2 0 -0.0016 14 0 0 0 0.00E+00 0.00E+00 - - - 3.1298 0.9998 221125_WJC_METTL3_EV_vs_WT_F04.14477.14477.2 0.00137 14/18 R.RIDISPSTFR.K "sp|Q9Y2W1|TR150_HUMAN,tr|A0A3B3ITZ9|A0A3B3ITZ9_HUMAN" 2 1190.6408 3.01 48453 14477 2 1190.640906 596.3277 Thyroid hormone receptor-associated protein 3 OS=Homo sapiens OX=9606 GN=THRAP3 PE=1 SV=2 9.6 2668.1 - 4.86E+06 - - - 0.1134 - 2.56 0.329 - 344 1 2 0 0.0001 10 0 0 0 1.41E+08 4.66E+07 - - - 4.0948 0.9998 221125_WJC_METTL3_EV_vs_WT_F04.14479.14479.2 0.000286 16-Sep R.DYQELMNTK.L sp|P04264|K2C1_HUMAN 1 1140.5121 4388.48 48455 14479 2 1140.513601 571.2633 "Keratin, type II cytoskeletal 1 OS=Homo sapiens OX=9606 GN=KRT1 PE=1 SV=6" 4.37 2668.3 - 2.30E+07 - - - 1.2942 - 1.859 0.527 - 255.6 1 2 0 0.0015 9 0 0 0 7.38E+08 1.68E+05 - - - 4.7268 1 221125_WJC_METTL3_EV_vs_WT_F04.14480.14480.3 0.00542 16/52 K.TMDVIAEGDPGFK[136.11]R[166.11].T "sp|Q9NRY5|F1142_HUMAN,tr|E7ESJ7|E7ESJ7_HUMAN,tr|E5RGF9|E5RGF9_HUMAN" 3 1552.7674 1.41 48456 14480 3 1552.768462 518.5964 Protein FAM114A2 OS=Homo sapiens OX=9606 GN=FAM114A2 PE=1 SV=4 4.56 2668.3 - 2.26E+06 - - - 0.653 - 2.626 0.538 - 327.2 1 2 0 0.001 14 0 0 0 3.97E+07 2.82E+07 - - - 7.1036 0.9999 221125_WJC_METTL3_EV_vs_WT_F04.14482.14482.3 1.57E-05 16/48 R.DMLLANKVPAAAR.A "sp|Q8NHW5|RLA0L_HUMAN,sp|P05388|RLA0_HUMAN,tr|G3V210|G3V210_HUMAN,tr|F8VU65|F8VU65_HUMAN,tr|F8VWV4|F8VWV4_HUMAN,tr|F8VWS0|F8VWS0_HUMAN,tr|F8VW21|F8VW21_HUMAN,tr|F8VRK7|F8VRK7_HUMAN,tr|F8VQY6|F8VQY6_HUMAN,tr|F8VPE8|F8VPE8_HUMAN" 10 1368.7548 1.23 48458 14482 3 1368.755031 457.2589 60S acidic ribosomal protein P0-like OS=Homo sapiens OX=9606 GN=RPLP0P6 PE=5 SV=1 8.75 2668.5 - 1.58E+06 - - - 0.2016 - 2.661 0.472 - 316.4 1 2 1 0.0003 13 0 0 0 2.23E+07 1.81E+07 - - - 6.4558 0.9839 221125_WJC_METTL3_EV_vs_WT_F04.14483.14483.2 0.00182 22-Oct W.ELISNASDALDK.L "sp|Q58FF8|H90B2_HUMAN,sp|P08238|HS90B_HUMAN,sp|Q58FF6|H90B4_HUMAN,sp|Q58FF7|H90B3_HUMAN,sp|P14625|ENPL_HUMAN,tr|A0A7P0T917|A0A7P0T917_HUMAN,tr|A0A7P0Z405|A0A7P0Z405_HUMAN,tr|A0A7P0T823|A0A7P0T823_HUMAN,tr|A0A7P0TAE1|A0A7P0TAE1_HUMAN,tr|H0YIV0|H0YIV0_HUMAN,tr|A0A7P0T8R3|A0A7P0T8R3_HUMAN,tr|A0A7P0T885|A0A7P0T885_HUMAN,tr|A0A7P0TAY2|A0A7P0TAY2_HUMAN,tr|A0A087WT78|A0A087WT78_HUMAN,tr|F8W026|F8W026_HUMAN,tr|A0A7P0TBC2|A0A7P0TBC2_HUMAN,tr|A0A7P0TAT8|A0A7P0TAT8_HUMAN" 17 1274.6354 1.03 48459 14483 2 1274.635709 638.325 Putative heat shock protein HSP 90-beta 2 OS=Homo sapiens OX=9606 GN=HSP90AB2P PE=1 SV=2 4.03 2668.6 - 1.39E+06 - - - 0.2338 - 2.109 0.368 - 316 1 1 0 0.0003 12 0 0 0 1.34E+07 1.30E+07 - - - 3.7224 0.9902 221125_WJC_METTL3_EV_vs_WT_F04.14484.14484.2 0.000143 22-Dec W.ELISNASDALDK[136.11].L "sp|Q58FF8|H90B2_HUMAN,sp|P08238|HS90B_HUMAN,sp|Q58FF6|H90B4_HUMAN,sp|Q58FF7|H90B3_HUMAN,sp|P14625|ENPL_HUMAN,tr|A0A7P0T917|A0A7P0T917_HUMAN,tr|A0A7P0Z405|A0A7P0Z405_HUMAN,tr|A0A7P0T823|A0A7P0T823_HUMAN,tr|A0A7P0TAE1|A0A7P0TAE1_HUMAN,tr|H0YIV0|H0YIV0_HUMAN,tr|A0A7P0T8R3|A0A7P0T8R3_HUMAN,tr|A0A7P0T885|A0A7P0T885_HUMAN,tr|A0A7P0TAY2|A0A7P0TAY2_HUMAN,tr|A0A087WT78|A0A087WT78_HUMAN,tr|F8W026|F8W026_HUMAN,tr|A0A7P0TBC2|A0A7P0TBC2_HUMAN,tr|A0A7P0TAT8|A0A7P0TAT8_HUMAN" 17 1282.6496 1.03 48460 14484 2 1282.651573 642.3321 Putative heat shock protein HSP 90-beta 2 OS=Homo sapiens OX=9606 GN=HSP90AB2P PE=1 SV=2 4.03 2668.7 - 1.20E+06 - - - 1.5296 - 2.516 0.525 - 474.6 1 1 0 0.002 12 0 0 0 1.34E+07 1.30E+07 - - - 5.3457 0.9995 221125_WJC_METTL3_EV_vs_WT_F04.14485.14485.2 1.35E-05 22-Sep R.GEPPLPEEDLSK.L "sp|O15372|EIF3H_HUMAN,tr|B3KS98|B3KS98_HUMAN,tr|A0A087WZK9|A0A087WZK9_HUMAN" 3 1309.6402 38.56 48461 14485 2 1309.639217 655.8274 Eukaryotic translation initiation factor 3 subunit H OS=Homo sapiens OX=9606 GN=EIF3H PE=1 SV=1 4 2668.8 - 957141 - - - -0.7216 - 1.924 0.32 - 163 1 2 0 -0.0009 12 0 0 0 4.55E+07 1.18E+06 - - - 3.1261 0.9999 221125_WJC_METTL3_EV_vs_WT_F04.14487.14487.3 8.67E-05 Oct-68 K.IIKPLQYQSTVASGTVAR.V sp|Q13823|NOG2_HUMAN 1 1931.084 1.11 48463 14487 3 1931.08458 644.7019 Nucleolar GTP-binding protein 2 OS=Homo sapiens OX=9606 GN=GNL2 PE=1 SV=1 9.99 2669 - 652964 - - - 0.2947 - 2.044 0.442 - 90.6 1 2 0 0.0006 18 0 0 0 4.62E+06 4.15E+06 - - - 5.2479 0.9994 221125_WJC_METTL3_EV_vs_WT_F04.14488.14488.2 0.0054 18-Sep K.DTSVEDALER.T sp|Q96A35|RM24_HUMAN 1 1133.52 0.7 48464 14488 2 1133.521701 567.7673 "39S ribosomal protein L24, mitochondrial OS=Homo sapiens OX=9606 GN=MRPL24 PE=1 SV=1" 3.92 2669.2 - 642887 - - - 1.4592 - 1.964 0.325 - 396.1 1 2 0 0.0017 10 0 0 0 1.23E+07 1.76E+07 - - - 3.325 0.9446 221125_WJC_METTL3_EV_vs_WT_F04.14493.14493.3 0.402 Jul-36 K.HYEVEILDAK[136.11].T "sp|Q9NZ01|TECR_HUMAN,tr|M0R3C3|M0R3C3_HUMAN" 2 1223.6278 0.66 48469 14493 3 1223.626921 408.8832 Very-long-chain enoyl-CoA reductase OS=Homo sapiens OX=9606 GN=TECR PE=1 SV=1 4.65 2669.8 - 282791 - - - -0.6799 - 1.354 0.123 - 44.4 1 2 0 -0.0008 10 0 0 0 3.11E+06 4.72E+06 - - - 0.7962 1 221125_WJC_METTL3_EV_vs_WT_F04.14494.14494.2 0.262 13/28 K.GSVAEAEDC[160.03]YNTALR[166.11].L sp|O15294|OGT1_HUMAN 1 1664.734 1.29 48470 14494 2 1664.735609 833.3743 UDP-N-acetylglucosamine--peptide N-acetylglucosaminyltransferase 110 kDa subunit OS=Homo sapiens OX=9606 GN=OGT PE=1 SV=3 4.14 2669.9 - 201840 - - - 0.9845 - 2.945 0.599 - 638.6 1 2 0 0.0016 15 0 0 0 4.64E+06 3.59E+06 - - - 6.1202 0.9996 221125_WJC_METTL3_EV_vs_WT_F04.14495.14495.2 1.64E-05 14/26 K.QISGQYSGSPQLLK[136.11].N "sp|Q96N67|DOCK7_HUMAN,tr|A0A1B0GVW2|A0A1B0GVW2_HUMAN,tr|A0A1B0GUE9|A0A1B0GUE9_HUMAN" 3 1512.8028 0.64 48471 14495 2 1512.804988 757.4087 Dedicator of cytokinesis protein 7 OS=Homo sapiens OX=9606 GN=DOCK7 PE=1 SV=4 8.59 2670.1 - 427660 - - - 1.4741 - 2.116 0.394 - 383.1 1 2 0 0.0022 14 0 0 0 1.72E+06 2.68E+06 - - - 3.8313 0.9999 221125_WJC_METTL3_EV_vs_WT_F04.14496.14496.3 6.46E-07 13/56 K.FLADQQSEIDGLKGR.H "sp|P12270|TPR_HUMAN,tr|Q5SWX9|Q5SWX9_HUMAN" 2 1675.8529 8.56 48472 14496 3 1675.853363 559.6249 Nucleoprotein TPR OS=Homo sapiens OX=9606 GN=TPR PE=1 SV=3 4.56 2670.2 - 249888 - - - 0.247 - 2.465 0.59 - 151 1 2 1 0.0004 15 0 0 0 2.19E+06 2.56E+05 - - - 7.4719 0.9355 221125_WJC_METTL3_EV_vs_WT_F04.14498.14498.3 1.01 Sep-40 K.IRLENEIQTYR.S "sp|P13645|K1C10_HUMAN,tr|A0A1B0GVI3|A0A1B0GVI3_HUMAN" 2 1433.7627 82.78 48473 14498 3 1433.764542 478.9282 "Keratin, type I cytoskeletal 10 OS=Homo sapiens OX=9606 GN=KRT10 PE=1 SV=6" 6.14 2670.4 - 1.44E+06 - - - 1.3008 - 1.649 0.158 - 148.2 1 2 1 0.0019 11 0 0 0 1.77E+07 2.13E+05 - - - 1.7219 0.9992 221125_WJC_METTL3_EV_vs_WT_F04.14500.14500.3 0.000956 Dec-48 R.QIGVEHVVVYVNK[136.11].A sp|P49411|EFTU_HUMAN 1 1490.8337 1.44 48474 14500 3 1490.833868 497.9518 "Elongation factor Tu, mitochondrial OS=Homo sapiens OX=9606 GN=TUFM PE=1 SV=2" 6.75 2670.6 - 8.55E+06 - - - 0.1368 - 2.096 0.264 - 193 1 2 0 0.0002 13 0 0 0 1.97E+08 1.37E+08 - - - 3.4897 0.9999 221125_WJC_METTL3_EV_vs_WT_F04.14506.14506.2 6.72E-05 22-Oct K.NFGEEVDDESLK.E "sp|Q13310|PABP4_HUMAN,tr|A0A7I2V5W9|A0A7I2V5W9_HUMAN,tr|B1ANR0|B1ANR0_HUMAN,tr|A0A7I2V4L7|A0A7I2V4L7_HUMAN,tr|H0YCC8|H0YCC8_HUMAN,tr|A0A7I2V598|A0A7I2V598_HUMAN,tr|H0Y5F5|H0Y5F5_HUMAN" 7 1380.6045 1.12 48480 14506 2 1380.6034 691.3095 Polyadenylate-binding protein 4 OS=Homo sapiens OX=9606 GN=PABPC4 PE=1 SV=1 3.83 2671.1 - 642868 - - - -0.8004 - 1.971 0.537 - 283.1 1 2 0 -0.0011 12 0 0 0 5.93E+06 5.28E+06 - - - 4.7923 0.9997 221125_WJC_METTL3_EV_vs_WT_F04.14507.14507.3 0.000818 Dec-68 K.IIK[136.11]PLQYQSTVASGTVAR[166.11].V sp|Q13823|NOG2_HUMAN 1 1949.1065 1.11 48481 14507 3 1949.105809 650.7094 Nucleolar GTP-binding protein 2 OS=Homo sapiens OX=9606 GN=GNL2 PE=1 SV=1 9.99 2671.3 - 555523 - - - -0.3448 - 2.075 0.357 - 160 1 2 0 -0.0007 18 0 0 0 4.62E+06 4.15E+06 - - - 4.3377 0.9999 221125_WJC_METTL3_EV_vs_WT_F04.14508.14508.3 0.002 Dec-48 K.YSLYEVHVSGEER[166.11].R "tr|F8W9I4|F8W9I4_HUMAN,tr|E9PFY5|E9PFY5_HUMAN,tr|A8MQ02|A8MQ02_HUMAN" 3 1576.7397 0.92 48482 14508 3 1576.741742 526.5872 Afadin (Fragment) OS=Homo sapiens OX=9606 GN=AFDN PE=1 SV=1 4.75 2671.4 - 251339 - - - 1.2906 - 2.166 0.422 - 114.5 1 2 0 0.002 13 0 0 0 2.11E+06 2.29E+06 - - - 5.3398 1 221125_WJC_METTL3_EV_vs_WT_F04.14514.14514.2 5.91E-09 13/28 K.GSVAEAEDC[160.03]YNTALR.L sp|O15294|OGT1_HUMAN 1 1654.7257 1.29 48486 14514 2 1654.721744 828.3701 UDP-N-acetylglucosamine--peptide N-acetylglucosaminyltransferase 110 kDa subunit OS=Homo sapiens OX=9606 GN=OGT PE=1 SV=3 4.14 2672.1 - 502600 - - - -2.3907 - 2.68 0.642 - 559.4 1 2 0 -0.004 15 0 0 0 4.64E+06 3.59E+06 - - - 6.2052 0.9985 221125_WJC_METTL3_EV_vs_WT_F04.14517.14517.3 0.00397 13/52 K.QLILEGK[136.11]DPDLEAK[136.11].R sp|Q9Y6V7|DDX49_HUMAN 1 1583.8741 0.57 48489 14517 3 1583.874602 528.9653 Probable ATP-dependent RNA helicase DDX49 OS=Homo sapiens OX=9606 GN=DDX49 PE=1 SV=1 4.32 2672.5 - 369068 - - - 0.293 - 2.419 0.295 - 185.4 1 2 1 0.0005 14 0 0 0 3.15E+06 5.55E+06 - - - 4.1764 0.9999 221125_WJC_METTL3_EV_vs_WT_F04.14523.14523.2 0.00888 22-Dec R.DTDTLDLSGPAR.D "sp|O60231|DHX16_HUMAN,tr|A0A140T947|A0A140T947_HUMAN" 2 1259.5994 2.23 48493 14523 2 1259.599459 630.807 Pre-mRNA-splicing factor ATP-dependent RNA helicase DHX16 OS=Homo sapiens OX=9606 GN=DHX16 PE=1 SV=2 3.93 2673.3 - 604347 - - - 0.0786 - 2.56 0.42 - 678.5 1 2 0 0.0001 12 0 0 0 1.75E+07 7.84E+06 - - - 4.6164 0.9991 221125_WJC_METTL3_EV_vs_WT_F04.14527.14527.2 0.004 28-Oct R.IPQLAPPASDSTVTK[136.11].L sp|Q16513|PKN2_HUMAN 1 1531.8337 2.7 48497 14527 2 1531.83338 766.9241 Serine\threonine-protein kinase N2 OS=Homo sapiens OX=9606 GN=PKN2 PE=1 SV=1 5.84 2673.8 - 371334 - - - -0.2239 - 1.79 0.263 - 206.7 1 2 0 -0.0003 15 0 0 0 1.23E+07 4.58E+06 - - - 2.4148 0.9995 221125_WJC_METTL3_EV_vs_WT_F04.14528.14528.2 5.45E-05 24-Aug K.EFGSLPTTPSEQR[166.11].Q sp|O15400|STX7_HUMAN 1 1457.7026 1.09 48498 14528 2 1457.699899 729.8586 Syntaxin-7 OS=Homo sapiens OX=9606 GN=STX7 PE=1 SV=4 4.53 2674 - 320242 - - - -1.8481 - 1.735 0.463 - 90.4 1 2 0 -0.0027 13 0 0 0 4.03E+06 3.70E+06 - - - 3.874 1 221125_WJC_METTL3_EV_vs_WT_F04.14531.14531.3 0.000162 15/44 K.YPSLLLHSQEEK.T "sp|Q8IWZ3|ANKH1_HUMAN,tr|A0A0A0MQZ8|A0A0A0MQZ8_HUMAN,tr|H0Y472|H0Y472_HUMAN,tr|H0Y7Y3|H0Y7Y3_HUMAN,tr|H0Y4P6|H0Y4P6_HUMAN,tr|H0Y785|H0Y785_HUMAN" 6 1442.7405 1.47 48500 14531 3 1442.741937 481.9208 Ankyrin repeat and KH domain-containing protein 1 OS=Homo sapiens OX=9606 GN=ANKHD1 PE=1 SV=1 5.4 2674.3 - 1.31E+06 - - - 0.9648 - 3.093 0.495 - 213.3 1 2 0 0.0014 12 0 0 0 1.84E+07 1.25E+07 - - - 7.1882 0.9956 221125_WJC_METTL3_EV_vs_WT_F04.14535.14535.3 0.0289 Aug-40 K.EDHLMSAMNIK.L "sp|Q8IXK0|PHC2_HUMAN,sp|Q8NDX5|PHC3_HUMAN,tr|H7C528|H7C528_HUMAN,tr|A0A0A0MSI2|A0A0A0MSI2_HUMAN,tr|B3KPJ4|B3KPJ4_HUMAN" 5 1287.5951 2.87 48503 14535 3 1287.59441 430.2057 Polyhomeotic-like protein 2 OS=Homo sapiens OX=9606 GN=PHC2 PE=1 SV=1 5.32 2674.7 - 932160 - - - -0.5693 - 1.522 0.231 - 136.5 1 2 0 -0.0007 11 0 0 0 7.68E+06 2.67E+06 - - - 2.3084 0.9994 221125_WJC_METTL3_EV_vs_WT_F04.14537.14537.3 0.00434 14/52 K.QLILEGKDPDLEAK.R sp|Q9Y6V7|DDX49_HUMAN 1 1567.8457 0.57 48505 14537 3 1567.843865 523.6225 Probable ATP-dependent RNA helicase DDX49 OS=Homo sapiens OX=9606 GN=DDX49 PE=1 SV=1 4.32 2675 - 538846 - - - -1.1946 - 2.577 0.351 - 255.8 1 2 1 -0.0019 14 0 0 0 3.15E+06 5.55E+06 - - - 4.9685 0.9999 221125_WJC_METTL3_EV_vs_WT_F04.14540.14540.3 0.000184 Oct-40 K.KVPVSVNLLSK.N "sp|O76021|RL1D1_HUMAN,tr|J3QSV6|J3QSV6_HUMAN,tr|I3L3C4|I3L3C4_HUMAN" 3 1182.7336 0.87 48508 14540 3 1182.734654 395.2518 Ribosomal L1 domain-containing protein 1 OS=Homo sapiens OX=9606 GN=RSL1D1 PE=1 SV=3 10 2675.4 - 373174 - - - 0.8835 - 2.177 0.399 - 135.6 1 2 0 0.001 11 0 0 0 2.93E+06 3.38E+06 - - - 5.1982 1 221125_WJC_METTL3_EV_vs_WT_F04.14541.14541.3 2.44E-05 13/52 K.YIYDSAFHPDTGEK[136.11].M "sp|Q9H9B4|SFXN1_HUMAN,tr|D6RFI0|D6RFI0_HUMAN,tr|D6RDG7|D6RDG7_HUMAN,tr|S4R2X2|S4R2X2_HUMAN" 4 1649.7453 0.91 48509 14541 3 1649.745777 550.9224 Sideroflexin-1 OS=Homo sapiens OX=9606 GN=SFXN1 PE=1 SV=4 4.54 2675.5 - 338041 - - - 0.2879 - 2.06 0.544 - 96.7 1 2 0 0.0005 14 0 0 0 9.10E+06 1.00E+07 - - - 6.5255 0.8456 221125_WJC_METTL3_EV_vs_WT_F04.14544.14544.3 0.00676 13/52 K.LTDISVTDPEKYPH.M sp|Q9Y333|LSM2_HUMAN 1 1613.7937 1.26 48512 14544 3 1613.791925 538.9385 U6 snRNA-associated Sm-like protein LSm2 OS=Homo sapiens OX=9606 GN=LSM2 PE=1 SV=1 4.54 2675.9 - 229980 - - - -1.1018 - 2.031 0.328 - 175.3 1 1 1 -0.0018 14 0 0 0 3.50E+06 2.78E+06 - - - 4.0793 1 221125_WJC_METTL3_EV_vs_WT_F04.14547.14547.3 3.06E-05 Dec-44 K.TEELEEESFPER[166.11].S "sp|Q9Y2W1|TR150_HUMAN,tr|A0A3B3ITZ9|A0A3B3ITZ9_HUMAN" 2 1503.6605 3.09 48514 14547 3 1503.657524 502.2274 Thyroid hormone receptor-associated protein 3 OS=Homo sapiens OX=9606 GN=THRAP3 PE=1 SV=2 3.9 2676.3 - 708622 - - - -1.9479 - 2.524 0.544 - 202.7 1 2 0 -0.0029 12 0 0 0 4.53E+07 1.47E+07 - - - 7.1706 1 221125_WJC_METTL3_EV_vs_WT_F04.14548.14548.2 1.83E-07 24-Dec K.NVFSSSGTSFSGR.K sp|P49790|NU153_HUMAN 1 1331.6106 1.44 48515 14548 2 1331.616497 666.8126 Nuclear pore complex protein Nup153 OS=Homo sapiens OX=9606 GN=NUP153 PE=1 SV=2 9.75 2676.4 - 530506 - - - 4.4337 - 2.577 0.635 - 300.8 1 2 0 0.0059 13 0 0 0 2.88E+07 2.01E+07 - - - 6.1588 0.9997 221125_WJC_METTL3_EV_vs_WT_F04.14550.14550.3 0.00238 14/48 K.HALLDVTPNAVDR.L "sp|Q07157|ZO1_HUMAN,tr|A0A087X0K9|A0A087X0K9_HUMAN,tr|G5E9E7|G5E9E7_HUMAN,tr|A0A0G2JNH2|A0A0G2JNH2_HUMAN,tr|G3V1L9|G3V1L9_HUMAN,tr|A0A7I2V5U5|A0A7I2V5U5_HUMAN" 6 1419.747 0.49 48517 14550 3 1419.750101 474.2563 Tight junction protein ZO-1 OS=Homo sapiens OX=9606 GN=TJP1 PE=1 SV=3 5.21 2676.7 - 709233 - - - 2.1652 - 2.389 0.371 - 328.5 1 2 0 0.0031 13 0 0 0 4.76E+06 9.72E+06 - - - 5.0366 0.9992 221125_WJC_METTL3_EV_vs_WT_F04.14552.14552.2 0.000128 22-Sep R.DIIGVAETGSGK[136.11].T "sp|Q9BUQ8|DDX23_HUMAN,tr|H0YI52|H0YI52_HUMAN" 2 1153.607 2.36 48519 14552 2 1153.60969 577.8108 Probable ATP-dependent RNA helicase DDX23 OS=Homo sapiens OX=9606 GN=DDX23 PE=1 SV=3 4.37 2677 - 583724 - - - 2.3162 - 1.908 0.397 - 194.6 1 2 0 0.0027 12 0 0 0 3.64E+07 1.54E+07 - - - 3.6723 0.9999 221125_WJC_METTL3_EV_vs_WT_F04.14553.14553.3 1.94E-05 Dec-48 K.LIHPDEDISLEER[166.11].R "sp|O43670|ZN207_HUMAN,tr|J3QRS9|J3QRS9_HUMAN,tr|X6R4W8|X6R4W8_HUMAN,tr|J3KS31|J3KS31_HUMAN" 4 1574.7816 0.42 48520 14553 3 1574.783688 525.9345 BUB3-interacting and GLEBS motif-containing protein ZNF207 OS=Homo sapiens OX=9606 GN=ZNF207 PE=1 SV=1 4.17 2677.1 - 578509 - - - 1.3437 - 2.403 0.4 - 253.7 1 2 0 0.0021 13 0 0 0 4.40E+06 1.04E+07 - - - 5.3761 0.9999 221125_WJC_METTL3_EV_vs_WT_F04.14554.14554.2 0.00476 13/24 K.NVFSSSGTSFSGR[166.11].K sp|P49790|NU153_HUMAN 1 1341.6189 1.42 48521 14554 2 1341.619643 671.8167 Nuclear pore complex protein Nup153 OS=Homo sapiens OX=9606 GN=NUP153 PE=1 SV=2 9.75 2677.2 - 558985 - - - 0.5814 - 2.456 0.534 - 422.9 1 2 0 0.0008 13 0 0 0 2.86E+07 2.01E+07 - - - 5.291 0.9985 221125_WJC_METTL3_EV_vs_WT_F04.14555.14555.3 0.00047 Nov-40 K.IK[136.11]DLSTIEPLK[136.11].Q "sp|O43423|AN32C_HUMAN,sp|O95626|AN32D_HUMAN,sp|Q92688|AN32B_HUMAN,sp|P39687|AN32A_HUMAN,tr|H0YN26|H0YN26_HUMAN" 5 1271.7672 3.57 48522 14555 3 1271.767089 424.9297 Acidic leucine-rich nuclear phosphoprotein 32 family member C OS=Homo sapiens OX=9606 GN=ANP32C PE=2 SV=1 6.07 2677.4 - 555483 - - - -0.0511 - 2.198 0.302 - 164.8 1 2 1 -0.0001 11 0 0 0 1.64E+07 4.59E+06 - - - 4.1443 1 221125_WJC_METTL3_EV_vs_WT_F04.14558.14558.3 6.38E-05 Nov-36 K.KPVIVFVPSR.K sp|O75643|U520_HUMAN 1 1140.7019 0.09 48525 14558 3 1140.703194 381.2412 U5 small nuclear ribonucleoprotein 200 kDa helicase OS=Homo sapiens OX=9606 GN=SNRNP200 PE=1 SV=2 11 2677.7 - 348657 - - - 1.1212 - 2.377 0.499 - 273.5 1 2 0 0.0013 10 0 0 0 3.26E+06 3.55E+07 - - - 6.6316 0.9994 221125_WJC_METTL3_EV_vs_WT_F04.14563.14563.2 0.0014 26-Sep K.ELSTTLNADEAVTR[166.11].G "sp|P34932|HSP74_HUMAN,tr|A0A087WTS8|A0A087WTS8_HUMAN,tr|A0A087WYC1|A0A087WYC1_HUMAN" 3 1528.7608 0.81 48530 14563 2 1528.763741 765.3877 Heat shock 70 kDa protein 4 OS=Homo sapiens OX=9606 GN=HSPA4 PE=1 SV=4 4.14 2678.4 - 177148 - - - 1.9002 - 1.888 0.416 - 271 1 2 0 0.0029 14 0 0 0 3.51E+06 4.32E+06 - - - 3.7075 1 221125_WJC_METTL3_EV_vs_WT_F04.14567.14567.2 5.18E-05 14/24 R.C[160.03]QVFEETQIGGER[166.11].Y sp|Q99832|TCPH_HUMAN 1 1561.707 0.13 48532 14567 2 1561.708093 781.8608 T-complex protein 1 subunit eta OS=Homo sapiens OX=9606 GN=CCT7 PE=1 SV=2 4.25 2678.8 - 1.72E+06 - - - 0.6826 - 2.615 0.601 - 672.1 1 2 0 0.0011 13 0 0 0 5.67E+06 4.29E+07 - - - 5.9468 1 221125_WJC_METTL3_EV_vs_WT_F04.14568.14568.3 8.83E-09 17/52 K.YIYDSAFHPDTGEK.M "sp|Q9H9B4|SFXN1_HUMAN,tr|D6RFI0|D6RFI0_HUMAN,tr|D6RDG7|D6RDG7_HUMAN,tr|S4R2X2|S4R2X2_HUMAN" 4 1641.7311 0.91 48533 14568 3 1641.732385 548.251 Sideroflexin-1 OS=Homo sapiens OX=9606 GN=SFXN1 PE=1 SV=4 4.54 2678.9 - 1.05E+06 - - - 0.7815 - 2.805 0.659 - 199.1 1 2 0 0.0013 14 0 0 0 9.10E+06 1.00E+07 - - - 8.6278 0.9999 221125_WJC_METTL3_EV_vs_WT_F04.14569.14569.2 2.12E-07 14/24 K.GAAPNVVYTYTGK[136.11].R "sp|Q16630|CPSF6_HUMAN,tr|A0A3B3ISW1|A0A3B3ISW1_HUMAN,tr|F8W084|F8W084_HUMAN,tr|F8WJN3|F8WJN3_HUMAN" 4 1347.6914 0.45 48534 14569 2 1347.68933 674.853 Cleavage and polyadenylation specificity factor subunit 6 OS=Homo sapiens OX=9606 GN=CPSF6 PE=1 SV=2 8.5 2679 - 1.02E+06 - - - -1.5478 - 2.523 0.569 - 734.3 1 2 0 -0.0021 13 0 0 0 3.80E+06 8.35E+06 - - - 5.6182 1 221125_WJC_METTL3_EV_vs_WT_F04.14571.14571.2 5.27E-05 13/22 R.DTDTLDLSGPAR[166.11].D "sp|O60231|DHX16_HUMAN,tr|A0A140T947|A0A140T947_HUMAN" 2 1269.6076 2.25 48536 14571 2 1269.609043 635.8111 Pre-mRNA-splicing factor ATP-dependent RNA helicase DHX16 OS=Homo sapiens OX=9606 GN=DHX16 PE=1 SV=2 3.93 2679.3 - 890077 - - - 1.1129 - 2.604 0.585 - 723.6 1 2 0 0.0014 12 0 0 0 1.77E+07 7.84E+06 - - - 5.8795 0.9999 221125_WJC_METTL3_EV_vs_WT_F04.14575.14575.3 0.000154 16/36 K.QNRPIPQWIR.M "sp|P62891|RL39_HUMAN,sp|Q59GN2|R39L5_HUMAN" 2 1306.7258 0.61 48540 14575 3 1306.727058 436.5826 60S ribosomal protein L39 OS=Homo sapiens OX=9606 GN=RPL39 PE=1 SV=2 12 2679.7 - 663230 - - - 0.9336 - 2.45 0.402 - 500.9 1 2 0 0.0012 10 0 0 0 2.89E+07 4.74E+07 - - - 5.6385 0.9996 221125_WJC_METTL3_EV_vs_WT_F04.14576.14576.2 2.99E-05 20-Dec K.QQVYQLGGIC[160.03]K.L sp|Q13835|PKP1_HUMAN 1 1292.6547 5.5 48541 14576 2 1292.65794 647.3346 Plakophilin-1 OS=Homo sapiens OX=9606 GN=PKP1 PE=1 SV=2 8.2 2679.9 - 662468 - - - 2.5011 - 2.508 0.446 - 754.3 1 2 0 0.0032 11 0 0 0 8.91E+06 1.62E+06 - - - 4.8216 1 221125_WJC_METTL3_EV_vs_WT_F04.14577.14577.3 8.07E-05 14/48 R.C[160.03]QVFEETQIGGER[166.11].Y sp|Q99832|TCPH_HUMAN 1 1561.707 0.37 48542 14577 3 1561.709187 521.5763 T-complex protein 1 subunit eta OS=Homo sapiens OX=9606 GN=CCT7 PE=1 SV=2 4.25 2679.9 - 619722 - - - 1.3831 - 2.311 0.541 - 300.7 1 2 0 0.0022 13 0 0 0 4.55E+06 1.24E+07 - - - 6.8422 0.9929 221125_WJC_METTL3_EV_vs_WT_F04.14580.14580.3 8.69E-05 Sep-40 A.RAAEVWMDEYK.E "sp|Q8N4A0|GALT4_HUMAN,sp|Q10471|GALT2_HUMAN,tr|F8VUJ3|F8VUJ3_HUMAN" 3 1396.6445 1.15 48545 14580 3 1396.646291 466.5555 Polypeptide N-acetylgalactosaminyltransferase 4 OS=Homo sapiens OX=9606 GN=GALNT4 PE=1 SV=2 4.68 2680.3 - 465849 - - - 1.2566 - 1.629 0.528 - 126.4 1 1 0 0.0018 11 0 0 0 2.55E+06 2.22E+06 - - - 5.8124 0.9997 221125_WJC_METTL3_EV_vs_WT_F04.14582.14582.3 3.03E-07 14/68 K.GYLGAVKPLAGAAGAPGK.G sp|O00257|CBX4_HUMAN 1 1596.8988 1.73 48547 14582 3 1596.905551 533.3069 E3 SUMO-protein ligase CBX4 OS=Homo sapiens OX=9606 GN=CBX4 PE=1 SV=3 9.7 2680.6 - 426941 - - - 4.242 - 2.488 0.494 - 148.3 1 2 0 0.0068 18 0 0 0 2.59E+06 1.49E+06 - - - 6.3154 0.9993 221125_WJC_METTL3_EV_vs_WT_F04.14583.14583.2 1.53E-08 14/26 R.FESLEPEMNNQASR.V "sp|Q01082|SPTB2_HUMAN,tr|A0A087WUZ3|A0A087WUZ3_HUMAN" 2 1650.7308 2.34 48548 14583 2 1650.736527 826.3727 "Spectrin beta chain, non-erythrocytic 1 OS=Homo sapiens OX=9606 GN=SPTBN1 PE=1 SV=2" 4.25 2680.7 - 373118 - - - 3.4785 - 2.558 0.501 - 422.3 1 2 0 0.0057 14 0 0 0 4.50E+06 1.93E+06 - - - 5.0965 0.9811 221125_WJC_METTL3_EV_vs_WT_F04.14585.14585.3 1.02 Sep-36 R.R[166.11]INMVEELEK[136.11].A sp|Q15046|SYK_HUMAN 1 1277.6768 0.64 48550 14585 3 1277.680828 426.8996 Lysine--tRNA ligase OS=Homo sapiens OX=9606 GN=KARS1 PE=1 SV=3 4.79 2681 - 298434 - - - 3.1197 - 1.691 0.199 - 122.3 1 2 0 0.004 10 0 0 0 1.56E+06 2.42E+06 - - - 2.2917 0.9995 221125_WJC_METTL3_EV_vs_WT_F04.14588.14588.2 0.000685 26-Aug K.ATLLEDQQDPSPSS.- "sp|Q9HC35|EMAL4_HUMAN,tr|B5MBZ0|B5MBZ0_HUMAN" 2 1486.6787 - 48552 14588 2 1486.679662 744.3466 Echinoderm microtubule-associated protein-like 4 OS=Homo sapiens OX=9606 GN=EML4 PE=1 SV=3 3.49 2681.4 - 421211 - - - 0.6256 - 1.369 0.441 - 107.6 1 2 0 0.0009 14 0 0 0 - - - - - 3.0861 1 221125_WJC_METTL3_EV_vs_WT_F04.14589.14589.3 2.35E-10 16/56 R.VYNVTQHAVGIVVNK.Q "sp|P46778|RL21_HUMAN,tr|G3V1B3|G3V1B3_HUMAN,tr|M0R181|M0R181_HUMAN" 3 1639.9046 1.33 48553 14589 3 1639.908379 547.6421 60S ribosomal protein L21 OS=Homo sapiens OX=9606 GN=RPL21 PE=1 SV=2 8.57 2681.5 - 1.57E+06 - - - 2.3105 - 3.043 0.616 - 146.1 1 2 0 0.0038 15 0 0 0 1.12E+07 8.40E+06 - - - 8.3106 1 221125_WJC_METTL3_EV_vs_WT_F04.14590.14590.3 9.87E-09 13/56 R.VYNVTQHAVGIVVNK[136.11].Q "sp|P46778|RL21_HUMAN,tr|G3V1B3|G3V1B3_HUMAN,tr|M0R181|M0R181_HUMAN" 3 1647.9188 1.33 48554 14590 3 1647.921693 550.3135 60S ribosomal protein L21 OS=Homo sapiens OX=9606 GN=RPL21 PE=1 SV=2 8.57 2681.6 - 1.51E+06 - - - 1.7616 - 2.226 0.608 - 81.9 1 2 0 0.0029 15 0 0 0 1.12E+07 8.40E+06 - - - 7.4058 0.9946 221125_WJC_METTL3_EV_vs_WT_F04.14592.14592.3 0.000292 Dec-44 L.RMSVEADINGLR.R "sp|P02533|K1C14_HUMAN,sp|P08727|K1C19_HUMAN,tr|C9JM50|C9JM50_HUMAN" 3 1359.6929 40.86 48556 14592 3 1359.694497 454.2382 "Keratin, type I cytoskeletal 14 OS=Homo sapiens OX=9606 GN=KRT14 PE=1 SV=4" 6.07 2681.8 - 845486 - - - 1.187 - 2.518 0.448 - 298.5 1 1 0 0.0016 12 0 0 0 5.37E+07 1.31E+06 - - - 6.094 0.9998 221125_WJC_METTL3_EV_vs_WT_F04.14594.14594.3 6.28E-05 13/44 K.MLSSAYISDHMK.V "sp|P56270|MAZ_HUMAN,tr|I3L0M3|I3L0M3_HUMAN,tr|H3BQI4|H3BQI4_HUMAN,tr|H3BQS2|H3BQS2_HUMAN,tr|I3L2Z5|I3L2Z5_HUMAN,tr|I3L4Y2|I3L4Y2_HUMAN,tr|A0A087WWR2|A0A087WWR2_HUMAN,tr|I3L411|I3L411_HUMAN,tr|H3BPU3|H3BPU3_HUMAN" 9 1381.637 1.02 48558 14594 3 1381.637781 461.5529 Myc-associated zinc finger protein OS=Homo sapiens OX=9606 GN=MAZ PE=1 SV=1 6.49 2682 - 617018 - - - 0.5595 - 2.108 0.364 - 198.5 1 2 0 0.0008 12 0 0 0 5.68E+06 5.58E+06 - - - 4.6651 0.9998 221125_WJC_METTL3_EV_vs_WT_F04.14595.14595.3 0.000375 Nov-44 K.MLSSAYISDHMK[136.11].V "sp|P56270|MAZ_HUMAN,tr|I3L0M3|I3L0M3_HUMAN,tr|H3BQI4|H3BQI4_HUMAN,tr|H3BQS2|H3BQS2_HUMAN,tr|I3L2Z5|I3L2Z5_HUMAN,tr|I3L4Y2|I3L4Y2_HUMAN,tr|A0A087WWR2|A0A087WWR2_HUMAN,tr|I3L411|I3L411_HUMAN,tr|H3BPU3|H3BPU3_HUMAN" 9 1389.6512 1.02 48559 14595 3 1389.654174 464.2243 Myc-associated zinc finger protein OS=Homo sapiens OX=9606 GN=MAZ PE=1 SV=1 6.49 2682.1 - 540934 - - - 2.1343 - 1.904 0.431 - 119.7 1 2 0 0.003 12 0 0 0 5.68E+06 5.58E+06 - - - 5.1294 1 221125_WJC_METTL3_EV_vs_WT_F04.14598.14598.2 1.58E-08 15/28 K.LSNNPQLSC[160.03]SSSLIK[136.11].T sp|Q6ZU65|UBN2_HUMAN 1 1654.844 1.29 48562 14598 2 1654.846501 828.4293 Ubinuclein-2 OS=Homo sapiens OX=9606 GN=UBN2 PE=1 SV=2 8.22 2682.5 - 299076 - - - 1.5288 - 2.882 0.599 - 742.3 1 2 0 0.0025 15 0 0 0 4.24E+06 3.29E+06 - - - 6.0668 0.9999 221125_WJC_METTL3_EV_vs_WT_F04.14600.14600.2 5.13E-06 26-Sep R.FESLEPEMNNQASR[166.11].V "sp|Q01082|SPTB2_HUMAN,tr|A0A087WUZ3|A0A087WUZ3_HUMAN" 2 1660.7391 2.34 48564 14600 2 1660.73838 831.3768 "Spectrin beta chain, non-erythrocytic 1 OS=Homo sapiens OX=9606 GN=SPTBN1 PE=1 SV=2" 4.25 2682.7 - 281346 - - - -0.4064 - 2.195 0.562 - 150.6 1 2 0 -0.0007 14 0 0 0 4.50E+06 1.93E+06 - - - 5.1646 0.9999 221125_WJC_METTL3_EV_vs_WT_F04.14603.14603.2 6.69E-07 26-Nov R.SFSPLQPGQAPTGR.A "sp|Q7Z3C6|ATG9A_HUMAN,tr|H7C1G6|H7C1G6_HUMAN,tr|H7C152|H7C152_HUMAN" 3 1441.7314 1.35 48567 14603 2 1441.732537 721.873 Autophagy-related protein 9A OS=Homo sapiens OX=9606 GN=ATG9A PE=1 SV=3 9.47 2683.1 - 195453 - - - 0.8046 - 2.229 0.517 - 225.1 1 2 0 0.0012 14 0 0 0 1.71E+06 1.27E+06 - - - 4.8707 0.9988 221125_WJC_METTL3_EV_vs_WT_F04.14608.14608.3 0.0183 Sep-44 K.TEELEEESFPER.S "sp|Q9Y2W1|TR150_HUMAN,tr|A0A3B3ITZ9|A0A3B3ITZ9_HUMAN" 2 1493.6522 3.09 48571 14608 3 1493.65474 498.8913 Thyroid hormone receptor-associated protein 3 OS=Homo sapiens OX=9606 GN=THRAP3 PE=1 SV=2 3.9 2683.7 - 898746 - - - 1.7119 - 1.736 0.31 - 119 1 2 0 0.0026 12 0 0 0 4.53E+07 1.47E+07 - - - 3.5244 0.9994 221125_WJC_METTL3_EV_vs_WT_F04.14610.14610.2 0.000218 20-Nov K.ASVSQVEADLK.M sp|Q07065|CKAP4_HUMAN 1 1145.5928 2.35 48572 14610 2 1145.594172 573.8037 Cytoskeleton-associated protein 4 OS=Homo sapiens OX=9606 GN=CKAP4 PE=1 SV=2 4.37 2684 - 2.59E+06 - - - 1.1819 - 2.057 0.298 - 508.8 1 2 0 0.0014 11 0 0 0 3.63E+07 1.55E+07 - - - 3.1928 0.9999 221125_WJC_METTL3_EV_vs_WT_F04.14611.14611.2 6.26E-07 13/28 R.LEGEVTPNSLSTSYK.T "sp|Q8IWZ3|ANKH1_HUMAN,tr|A0A0A0MQZ8|A0A0A0MQZ8_HUMAN,tr|H0Y472|H0Y472_HUMAN,tr|H0Y7Y3|H0Y7Y3_HUMAN,tr|H0Y4P6|H0Y4P6_HUMAN,tr|H0Y785|H0Y785_HUMAN" 6 1623.7992 1.53 48573 14611 2 1623.801278 812.9069 Ankyrin repeat and KH domain-containing protein 1 OS=Homo sapiens OX=9606 GN=ANKHD1 PE=1 SV=1 4.53 2684 - 2.43E+06 - - - 1.2908 - 2.698 0.517 - 495.6 1 2 0 0.0021 15 0 0 0 3.59E+07 2.34E+07 - - - 5.299 0.9999 221125_WJC_METTL3_EV_vs_WT_F04.14612.14612.2 1.05E-05 16/26 K.SALAAAQTQVAEYK.Q sp|O00461|GOLI4_HUMAN 1 1449.7464 1.37 48574 14612 2 1449.746757 725.8805 Golgi integral membrane protein 4 OS=Homo sapiens OX=9606 GN=GOLIM4 PE=1 SV=1 5.72 2684.1 - 1.76E+06 - - - 0.2752 - 2.985 0.502 - 740.1 1 2 0 0.0004 14 0 0 0 1.26E+07 9.19E+06 - - - 5.493 1 221125_WJC_METTL3_EV_vs_WT_F04.14613.14613.3 2.27E-08 14/52 R.DAYSGGAVNLYHVR[166.11].E sp|P28074|PSB5_HUMAN 1 1530.7455 0.8 48575 14613 3 1530.743878 511.2558 Proteasome subunit beta type-5 OS=Homo sapiens OX=9606 GN=PSMB5 PE=1 SV=3 6.74 2684.1 - 1.27E+06 - - - -1.0341 - 2.651 0.604 - 157 1 2 0 -0.0016 14 0 0 0 1.68E+07 2.10E+07 - - - 7.8645 1 221125_WJC_METTL3_EV_vs_WT_F04.14614.14614.3 8.40E-08 15/60 R.VVVLMGSTSDLGHC[160.03]EK[136.11].L "sp|P22234|PUR6_HUMAN,tr|D6RF62|D6RF62_HUMAN,tr|E9PBS1|E9PBS1_HUMAN" 3 1738.8473 0.74 48576 14614 3 1738.847472 580.6231 Multifunctional protein ADE2 OS=Homo sapiens OX=9606 GN=PAICS PE=1 SV=3 5.32 2684.2 - 973004 - - - 0.0748 - 3.133 0.651 - 226.2 1 2 0 0.0001 16 0 0 0 5.17E+06 7.03E+06 - - - 8.7282 0.9997 221125_WJC_METTL3_EV_vs_WT_F04.14617.14617.2 0.000272 16-Dec R.HILEMNFSK[136.11].A "sp|O95785|WIZ_HUMAN,tr|A0A669KBG4|A0A669KBG4_HUMAN,tr|A0A2R8YFV2|A0A2R8YFV2_HUMAN,tr|A0A669KAV7|A0A669KAV7_HUMAN,tr|M0QXA7|M0QXA7_HUMAN,tr|A0A669KBH9|A0A669KBH9_HUMAN,tr|B9EGQ5|B9EGQ5_HUMAN" 7 1125.5732 0.98 48579 14617 2 1125.576188 563.7939 Protein Wiz OS=Homo sapiens OX=9606 GN=WIZ PE=1 SV=2 6.75 2684.5 - 821694 - - - 2.6413 - 2.318 0.548 - 520.8 1 2 0 0.003 9 0 0 0 5.58E+06 5.67E+06 - - - 5.5198 0.9999 221125_WJC_METTL3_EV_vs_WT_F04.14618.14618.3 6.27E-07 Nov-60 R.GLTGGFGSHSVC[160.03]GGFR.A "sp|Q14533|KRT81_HUMAN,sp|O43790|KRT86_HUMAN,sp|P78385|KRT83_HUMAN,tr|A0A087X106|A0A087X106_HUMAN,tr|U3KPR1|U3KPR1_HUMAN" 5 1594.7311 56.32 48580 14618 3 1594.735434 532.5843 "Keratin, type II cuticular Hb1 OS=Homo sapiens OX=9606 GN=KRT81 PE=1 SV=3" 8.26 2684.6 - 820823 - - - 2.7428 - 2.211 0.507 - 77.5 1 2 0 0.0044 16 0 0 0 3.02E+06 5.36E+04 - - - 6.2272 1 221125_WJC_METTL3_EV_vs_WT_F04.14619.14619.2 2.60E-10 15/28 K.LSNNPQLSC[160.03]SSSLIK.T sp|Q6ZU65|UBN2_HUMAN 1 1646.8298 1.29 48581 14619 2 1646.832285 824.4222 Ubinuclein-2 OS=Homo sapiens OX=9606 GN=UBN2 PE=1 SV=2 8.22 2684.8 - 809826 - - - 1.5266 - 2.959 0.595 - 697.7 1 2 0 0.0025 15 0 0 0 4.24E+06 3.29E+06 - - - 6.102 0.9994 221125_WJC_METTL3_EV_vs_WT_F04.14620.14620.2 8.01E-05 16-Aug K.EVSYNWDPK.D "sp|O14654|IRS4_HUMAN,tr|A0A804CF45|A0A804CF45_HUMAN" 2 1136.5138 0.77 48582 14620 2 1136.511264 569.2642 Insulin receptor substrate 4 OS=Homo sapiens OX=9606 GN=IRS4 PE=1 SV=1 4.37 2684.9 - 635715 - - - -2.2657 - 1.491 0.5 - 208.4 1 2 0 -0.0026 9 0 0 0 1.12E+07 1.47E+07 - - - 3.8888 0.9998 221125_WJC_METTL3_EV_vs_WT_F04.14621.14621.2 0.00574 14/22 R.QLVTETLQQASR[166.11].V "sp|Q7Z589|EMSY_HUMAN,tr|H0YCS3|H0YCS3_HUMAN,tr|E9PMC9|E9PMC9_HUMAN" 3 1382.7393 0.93 48583 14621 2 1382.742178 692.3769 BRCA2-interacting transcriptional repressor EMSY OS=Homo sapiens OX=9606 GN=EMSY PE=1 SV=2 6 2685 - 625029 - - - 2.072 - 2.732 0.48 - 961.2 1 2 0 0.0029 12 0 0 0 3.73E+06 4.02E+06 - - - 5.2298 0.9997 221125_WJC_METTL3_EV_vs_WT_F04.14622.14622.3 1.27E-07 14/48 R.GDVANEDKLSLLK.S "sp|O75970|MPDZ_HUMAN,tr|F5H1U9|F5H1U9_HUMAN" 2 1400.7511 2.45 48584 14622 3 1400.753987 467.9243 Multiple PDZ domain protein OS=Homo sapiens OX=9606 GN=MPDZ PE=1 SV=2 4.56 2685.1 - 588242 - - - 2.0546 - 2.607 0.492 - 260.4 1 2 1 0.0029 13 0 0 0 4.01E+06 1.64E+06 - - - 6.6225 1 221125_WJC_METTL3_EV_vs_WT_F04.14624.14624.2 0.00067 14/22 R.QLVTETLQQASR.V "sp|Q7Z589|EMSY_HUMAN,tr|H0YCS3|H0YCS3_HUMAN,tr|E9PMC9|E9PMC9_HUMAN" 3 1372.731 0.93 48586 14624 2 1372.73302 687.3728 BRCA2-interacting transcriptional repressor EMSY OS=Homo sapiens OX=9606 GN=EMSY PE=1 SV=2 6 2685.4 - 543205 - - - 1.4402 - 2.736 0.556 - 564 1 2 0 0.002 12 0 0 0 3.73E+06 4.02E+06 - - - 5.7953 1 221125_WJC_METTL3_EV_vs_WT_F04.14626.14626.3 6.11E-07 Dec-48 R.C[160.03]QVFEETQIGGER.Y sp|Q99832|TCPH_HUMAN 1 1551.6988 0.17 48588 14626 3 1551.697903 518.2402 T-complex protein 1 subunit eta OS=Homo sapiens OX=9606 GN=CCT7 PE=1 SV=2 4.25 2685.6 - 431459 - - - -0.5504 - 2.096 0.544 - 245.7 1 2 0 -0.0009 13 0 0 0 1.81E+06 1.06E+07 - - - 6.6113 0.996 221125_WJC_METTL3_EV_vs_WT_F04.14627.14627.2 0.0725 26-Oct R.VASALPGMENVQEK.S sp|Q9NRW1|RAB6B_HUMAN 1 1471.7341 1.52 48589 14627 2 1471.737503 736.8743 Ras-related protein Rab-6B OS=Homo sapiens OX=9606 GN=RAB6B PE=1 SV=1 4.53 2685.8 - 429830 - - - 2.3265 - 1.607 0.251 - 206.9 1 2 0 0.0034 14 0 0 0 4.83E+06 3.17E+06 - - - 2.0842 1 221125_WJC_METTL3_EV_vs_WT_F04.14629.14629.2 9.18E-07 30-Dec K.AFSSPQEEEEAGFTGR.R "sp|Q14241|ELOA1_HUMAN,tr|A0A024RAC6|A0A024RAC6_HUMAN" 2 1740.7591 1.24 48591 14629 2 1740.758717 871.3868 Elongin-A OS=Homo sapiens OX=9606 GN=ELOA PE=1 SV=2 4.09 2686 - 383410 - - - -0.2246 - 2.792 0.678 - 442.7 1 2 0 -0.0004 16 0 0 0 7.82E+06 6.32E+06 - - - 6.5729 0.9998 221125_WJC_METTL3_EV_vs_WT_F04.14631.14631.3 7.37E-05 Dec-36 K.QNR[166.11]PIPQWIR[166.11].M "sp|P62891|RL39_HUMAN,sp|Q59GN2|R39L5_HUMAN" 2 1326.7424 0.6 48592 14631 3 1326.743863 443.2547 60S ribosomal protein L39 OS=Homo sapiens OX=9606 GN=RPL39 PE=1 SV=2 12 2686.3 - 8.59E+06 - - - 1.1193 - 2.03 0.377 - 359.5 1 2 0 0.0015 10 0 0 0 2.89E+07 4.79E+07 - - - 4.8105 1 221125_WJC_METTL3_EV_vs_WT_F04.14633.14633.3 2.76E-05 16/52 R.DAYSGGAVNLYHVR.E sp|P28074|PSB5_HUMAN 1 1520.7372 0.81 48594 14633 3 1520.738582 507.9197 Proteasome subunit beta type-5 OS=Homo sapiens OX=9606 GN=PSMB5 PE=1 SV=3 6.74 2686.4 - 2.03E+06 - - - 0.9147 - 2.815 0.544 - 230 1 2 0 0.0014 14 0 0 0 1.69E+07 2.10E+07 - - - 7.3551 1 221125_WJC_METTL3_EV_vs_WT_F04.14635.14635.3 2.62E-06 13/44 K.VTNEFVHINNLK.L sp|O00743|PPP6_HUMAN 1 1426.7569 0.54 48596 14635 3 1426.759381 476.5929 Serine\threonine-protein phosphatase 6 catalytic subunit OS=Homo sapiens OX=9606 GN=PPP6C PE=1 SV=1 6.72 2686.6 - 1.12E+06 - - - 1.7641 - 2.485 0.511 - 249 1 2 0 0.0025 12 0 0 0 1.22E+07 2.25E+07 - - - 6.7596 0.9996 221125_WJC_METTL3_EV_vs_WT_F04.14636.14636.2 0.0055 20-Oct R.SETISVPQEIK.A "sp|O96033|MOC2A_HUMAN,tr|E9PKT9|E9PKT9_HUMAN" 2 1229.6503 2.31 48597 14636 2 1229.652101 615.8324 Molybdopterin synthase sulfur carrier subunit OS=Homo sapiens OX=9606 GN=MOCS2 PE=1 SV=1 4.53 2686.7 - 819312 - - - 1.4378 - 2.055 0.394 - 378.4 1 2 0 0.0018 11 0 0 0 4.74E+06 2.05E+06 - - - 3.899 0.9999 221125_WJC_METTL3_EV_vs_WT_F04.14639.14639.2 1.95E-08 14/30 K.AFSSPQEEEEAGFTGR[166.11].R "sp|Q14241|ELOA1_HUMAN,tr|A0A024RAC6|A0A024RAC6_HUMAN" 2 1750.7674 1.24 48600 14639 2 1750.768363 876.391 Elongin-A OS=Homo sapiens OX=9606 GN=ELOA PE=1 SV=2 4.09 2687.1 - 718607 - - - 0.5626 - 2.714 0.563 - 637.2 1 2 0 0.001 16 0 0 0 7.82E+06 6.32E+06 - - - 5.6537 1 221125_WJC_METTL3_EV_vs_WT_F04.14640.14640.2 6.96E-08 14/26 K.EDGLAQQQTQLNLR.S "sp|P49327|FAS_HUMAN,tr|A0A0U1RQF0|A0A0U1RQF0_HUMAN" 2 1612.8169 1.21 48601 14640 2 1612.817552 807.4157 Fatty acid synthase OS=Homo sapiens OX=9606 GN=FASN PE=1 SV=3 4.37 2687.2 - 584118 - - - 0.4055 - 2.977 0.611 - 981.3 1 2 0 0.0007 14 0 0 0 2.92E+06 2.41E+06 - - - 6.2912 1 221125_WJC_METTL3_EV_vs_WT_F04.14641.14641.2 6.06E-12 14/28 R.VFC[160.03]VEEEDSESSLQK[136.11].R sp|Q14684|RRP1B_HUMAN 1 1792.7917 0.5 48602 14641 2 1792.792773 897.4031 Ribosomal RNA processing protein 1 homolog B OS=Homo sapiens OX=9606 GN=RRP1B PE=1 SV=3 3.91 2687.4 - 558585 - - - 0.6203 - 2.81 0.709 - 611.5 1 2 0 0.0011 15 0 0 0 1.17E+06 2.34E+06 - - - 6.8175 0.9998 221125_WJC_METTL3_EV_vs_WT_F04.14642.14642.3 0.000371 Oct-52 K.SLGAEHVITEEELR[166.11].R "sp|Q9BV79|MECR_HUMAN,tr|H3BM30|H3BM30_HUMAN" 2 1591.8081 1.04 48603 14642 3 1591.809586 531.61 "Enoyl-[acyl-carrier-protein] reductase, mitochondrial OS=Homo sapiens OX=9606 GN=MECR PE=1 SV=2" 4.48 2687.4 - 482468 - - - 0.9203 - 1.842 0.422 - 84.4 1 2 0 0.0015 14 0 0 0 2.49E+06 2.40E+06 - - - 4.8678 1 221125_WJC_METTL3_EV_vs_WT_F04.14643.14643.2 4.88E-07 28-Dec R.VFC[160.03]VEEEDSESSLQK.R sp|Q14684|RRP1B_HUMAN 1 1784.7775 0.5 48604 14643 2 1784.777068 893.396 Ribosomal RNA processing protein 1 homolog B OS=Homo sapiens OX=9606 GN=RRP1B PE=1 SV=3 3.91 2687.6 - 442130 - - - -0.2202 - 2.514 0.647 - 407.4 1 2 0 -0.0004 15 0 0 0 1.17E+06 2.34E+06 - - - 6.0861 0.9991 221125_WJC_METTL3_EV_vs_WT_F04.14646.14646.2 0.000123 20-Oct R.SETISVPQEIK[136.11].A "sp|O96033|MOC2A_HUMAN,tr|E9PKT9|E9PKT9_HUMAN" 2 1237.6645 2.46 48607 14646 2 1237.668155 619.8395 Molybdopterin synthase sulfur carrier subunit OS=Homo sapiens OX=9606 GN=MOCS2 PE=1 SV=1 4.53 2688 - 359113 - - - 2.9265 - 1.779 0.472 - 373.8 1 2 0 0.0036 11 0 0 0 4.54E+06 1.85E+06 - - - 4.0844 1 221125_WJC_METTL3_EV_vs_WT_F04.14647.14647.2 1.28E-10 14/28 K.FSNQETSVEIGESVR.G "sp|P11908|PRPS2_HUMAN,tr|A6NMS2|A6NMS2_HUMAN,tr|D3YTJ7|D3YTJ7_HUMAN" 3 1680.7955 1.92 48608 14647 2 1680.797375 841.405 Ribose-phosphate pyrophosphokinase 2 OS=Homo sapiens OX=9606 GN=PRPS2 PE=1 SV=2 4.25 2688.1 - 238720 - - - 1.1191 - 2.664 0.645 - 637.6 1 2 0 0.0019 15 0 0 0 4.53E+06 2.35E+06 - - - 6.2133 0.9997 221125_WJC_METTL3_EV_vs_WT_F04.14648.14648.3 1.04E-05 Sep-60 K.AFSSPQEEEEAGFTGR[166.11].R "sp|Q14241|ELOA1_HUMAN,tr|A0A024RAC6|A0A024RAC6_HUMAN" 2 1750.7674 1.11 48609 14648 3 1750.766947 584.5964 Elongin-A OS=Homo sapiens OX=9606 GN=ELOA PE=1 SV=2 4.09 2688.2 - 222962 - - - -0.2462 - 2.316 0.314 - 76.3 1 2 0 -0.0004 16 0 0 0 1.71E+06 1.53E+06 - - - 4.1956 1 221125_WJC_METTL3_EV_vs_WT_F04.14649.14649.2 7.25E-08 14/26 R.DAYSGGAVNLYHVR[166.11].E sp|P28074|PSB5_HUMAN 1 1530.7455 1.5 48610 14649 2 1530.74636 766.38 Proteasome subunit beta type-5 OS=Homo sapiens OX=9606 GN=PSMB5 PE=1 SV=3 6.74 2688.4 - 172926 - - - 0.5873 - 2.797 0.619 - 471.6 1 2 0 0.0009 14 0 0 0 2.40E+06 1.60E+06 - - - 6.1937 0.9999 221125_WJC_METTL3_EV_vs_WT_F04.14652.14652.2 9.38E-07 14/28 R.LEGEVTPNSLSTSYK[136.11].T "sp|Q8IWZ3|ANKH1_HUMAN,tr|A0A0A0MQZ8|A0A0A0MQZ8_HUMAN,tr|H0Y472|H0Y472_HUMAN,tr|H0Y7Y3|H0Y7Y3_HUMAN,tr|H0Y4P6|H0Y4P6_HUMAN,tr|H0Y785|H0Y785_HUMAN" 6 1631.8134 1.53 48612 14652 2 1631.814834 816.914 Ankyrin repeat and KH domain-containing protein 1 OS=Homo sapiens OX=9606 GN=ANKHD1 PE=1 SV=1 4.53 2688.7 - 2.97E+06 - - - 0.8898 - 2.914 0.541 - 552.2 1 2 0 0.0015 15 0 0 0 3.59E+07 2.34E+07 - - - 5.6659 0.9994 221125_WJC_METTL3_EV_vs_WT_F04.14654.14654.3 0.000117 Dec-36 R.IKFEMEQNLR.Q "sp|P35527|K1C9_HUMAN,tr|K7EQQ3|K7EQQ3_HUMAN" 2 1306.6704 49759.05 48614 14654 3 1306.673408 436.5641 "Keratin, type I cytoskeletal 9 OS=Homo sapiens OX=9606 GN=KRT9 PE=1 SV=3" 6.14 2688.9 - 4.29E+07 - - - 2.3349 - 2.33 0.433 - 276.4 1 2 1 0.0031 10 0 0 0 2.14E+09 4.30E+04 - - - 5.837 0.9958 221125_WJC_METTL3_EV_vs_WT_F04.14655.14655.2 0.000344 18-Nov R.IKFEMEQNLR.Q "sp|P35527|K1C9_HUMAN,tr|K7EQQ3|K7EQQ3_HUMAN" 2 1306.6704 999 48615 14655 2 1306.671679 654.3425 "Keratin, type I cytoskeletal 9 OS=Homo sapiens OX=9606 GN=KRT9 PE=1 SV=3" 6.14 2688.9 - 3.93E+06 - - - 1.0117 - 2.029 0.356 - 321.2 1 2 1 0.0013 10 0 0 0 2.57E+08 0.00E+00 - - - 3.645 0.9999 221125_WJC_METTL3_EV_vs_WT_F04.14656.14656.2 2.40E-05 22-Dec K.NVQDAIADAEQR.G sp|P35908|K22E_HUMAN 1 1328.6321 220.32 48616 14656 2 1328.633413 665.3233 "Keratin, type II cytoskeletal 2 epidermal OS=Homo sapiens OX=9606 GN=KRT2 PE=1 SV=2" 4.03 2689 - 3.72E+06 - - - 1.0206 - 2.55 0.528 - 474.8 1 2 0 0.0014 12 0 0 0 1.19E+08 5.41E+05 - - - 5.4034 0.9998 221125_WJC_METTL3_EV_vs_WT_F04.14658.14658.3 2.88E-05 Dec-60 K.LVGLTGTREEVDQVAR.A "sp|O75880|SCO1_HUMAN,tr|J3QL56|J3QL56_HUMAN" 2 1741.9323 1.21 48618 14658 3 1741.933428 581.6514 "Protein SCO1 homolog, mitochondrial OS=Homo sapiens OX=9606 GN=SCO1 PE=1 SV=1" 4.68 2689.1 - 2.22E+06 - - - 0.6694 - 1.792 0.554 - 129.4 1 2 1 0.0012 16 0 0 0 9.16E+06 7.57E+06 - - - 6.213 1 221125_WJC_METTL3_EV_vs_WT_F04.14659.14659.3 7.04E-05 Dec-44 K.GSGNLEAIHIIK[136.11].K "sp|P78371|TCPB_HUMAN,tr|F8VQ14|F8VQ14_HUMAN,tr|F5GWF6|F5GWF6_HUMAN" 3 1258.7125 0.61 48619 14659 3 1258.713555 420.5781 T-complex protein 1 subunit beta OS=Homo sapiens OX=9606 GN=CCT2 PE=1 SV=4 6.75 2689.1 - 1.68E+06 - - - 0.8493 - 2.695 0.475 - 243.9 1 2 0 0.0011 12 0 0 0 2.04E+08 3.36E+08 - - - 6.5835 1 221125_WJC_METTL3_EV_vs_WT_F04.14661.14661.3 0.00356 17/36 R.SIHDALC[160.03]VIR[166.11].C "sp|P50991|TCPD_HUMAN,sp|P48643|TCPE_HUMAN,tr|E9PCA1|E9PCA1_HUMAN,tr|B7ZAR1|B7ZAR1_HUMAN,tr|E7ENZ3|E7ENZ3_HUMAN" 5 1192.6262 0.32 48621 14661 3 1192.627121 398.5493 T-complex protein 1 subunit delta OS=Homo sapiens OX=9606 GN=CCT4 PE=1 SV=4 6.46 2689.3 - 1.46E+06 - - - 0.7748 - 2.639 0.443 - 551.1 1 2 0 0.0009 10 0 0 0 3.14E+07 9.84E+07 - - - 6.3127 1 221125_WJC_METTL3_EV_vs_WT_F04.14662.14662.2 9.54E-09 17/34 L.SVAGGGGGFGAAGGFGGR.G sp|P35908|K22E_HUMAN 1 1437.6749 999 48622 14662 2 1437.675957 719.8447 "Keratin, type II cytoskeletal 2 epidermal OS=Homo sapiens OX=9606 GN=KRT2 PE=1 SV=2" 9.47 2689.4 - 1.36E+06 - - - 0.7178 - 3.892 0.651 - 803.5 1 1 0 0.001 18 0 0 0 1.29E+07 0.00E+00 - - - 7.1899 0.9412 221125_WJC_METTL3_EV_vs_WT_F04.14666.14666.3 0.234 Aug-40 R.SK[136.11]LTENLVALK[136.11].E "sp|Q00537|CDK17_HUMAN,sp|Q07002|CDK18_HUMAN,tr|A0A0A0MSJ6|A0A0A0MSJ6_HUMAN,tr|F5H6Z0|F5H6Z0_HUMAN" 4 1230.7518 1.55 48626 14666 3 1230.750858 411.2579 Cyclin-dependent kinase 17 OS=Homo sapiens OX=9606 GN=CDK17 PE=1 SV=2 8.31 2689.8 - 456708 - - - -0.7963 - 1.768 0.132 - 71.1 1 2 1 -0.001 11 0 0 0 3.05E+06 1.96E+06 - - - 1.6302 0.9984 221125_WJC_METTL3_EV_vs_WT_F04.14668.14668.3 0.0159 Oct-44 K.GGFLPPEEIK[136.11]ER[166.11].F sp|Q9H0D6|XRN2_HUMAN 1 1388.7419 1.1 48628 14668 3 1388.742618 463.9212 5'-3' exoribonuclease 2 OS=Homo sapiens OX=9606 GN=XRN2 PE=1 SV=1 4.79 2690 - 451911 - - - 0.5278 - 2.038 0.321 - 88.4 1 2 1 0.0007 12 0 0 0 3.18E+06 2.87E+06 - - - 4.0921 0.9999 221125_WJC_METTL3_EV_vs_WT_F04.14669.14669.3 3.55E-06 13/52 K.HTLVEADIGIQAER.V "sp|Q01082|SPTB2_HUMAN,tr|A0A087WUZ3|A0A087WUZ3_HUMAN,tr|F8W6C1|F8W6C1_HUMAN" 3 1550.8053 2.36 48629 14669 3 1550.809284 517.9424 "Spectrin beta chain, non-erythrocytic 1 OS=Homo sapiens OX=9606 GN=SPTBN1 PE=1 SV=2" 4.65 2690.2 - 437480 - - - 2.5883 - 2.574 0.469 - 193.2 1 2 0 0.004 14 0 0 0 4.86E+06 2.06E+06 - - - 6.2804 0.9566 221125_WJC_METTL3_EV_vs_WT_F04.14670.14670.2 0.00093 13/16 L.KFEMEQNLR.Q "sp|P35527|K1C9_HUMAN,tr|K7EQQ3|K7EQQ3_HUMAN" 2 1193.5863 8.73 48630 14670 2 1193.582779 597.8004 "Keratin, type I cytoskeletal 9 OS=Homo sapiens OX=9606 GN=KRT9 PE=1 SV=3" 6.14 2690.3 - 413306 - - - -2.9441 - 2.157 0.406 - 602.3 1 1 0 -0.0035 9 0 0 0 1.68E+07 1.92E+06 - - - 4.2626 1 221125_WJC_METTL3_EV_vs_WT_F04.14671.14671.2 0.000177 16/28 K.FSNQETSVEIGESVR[166.11].G "sp|P11908|PRPS2_HUMAN,tr|A6NMS2|A6NMS2_HUMAN,tr|D3YTJ7|D3YTJ7_HUMAN" 3 1690.8038 1.88 48631 14671 2 1690.803486 846.4092 Ribose-phosphate pyrophosphokinase 2 OS=Homo sapiens OX=9606 GN=PRPS2 PE=1 SV=2 4.25 2690.4 - 379205 - - - -0.1644 - 2.991 0.594 - 1054.8 1 2 0 -0.0003 15 0 0 0 4.42E+06 2.35E+06 - - - 6.1218 1 221125_WJC_METTL3_EV_vs_WT_F04.14673.14673.2 1.57E-07 26-Dec R.DAYSGGAVNLYHVR.E sp|P28074|PSB5_HUMAN 1 1520.7372 1.5 48632 14673 2 1520.743709 761.3759 Proteasome subunit beta type-5 OS=Homo sapiens OX=9606 GN=PSMB5 PE=1 SV=3 6.74 2690.8 - 248777 - - - 4.2861 - 2.448 0.636 - 311 1 2 0 0.0065 14 0 0 0 2.40E+06 1.60E+06 - - - 5.9831 0.9998 221125_WJC_METTL3_EV_vs_WT_F04.14675.14675.3 0.0015 Aug-44 K.NVQDAIADAEQR.G sp|P35908|K22E_HUMAN 1 1328.6321 22.38 48634 14675 3 1328.630331 443.8846 "Keratin, type II cytoskeletal 2 epidermal OS=Homo sapiens OX=9606 GN=KRT2 PE=1 SV=2" 4.03 2691 - 4.51E+06 - - - -1.2991 - 2.103 0.378 - 150.3 1 2 0 -0.0017 12 0 0 0 5.19E+07 2.32E+06 - - - 4.8143 0.9961 221125_WJC_METTL3_EV_vs_WT_F04.14677.14677.2 0.00015 16-Jul K.EVSYNWDPK[136.11].D "sp|O14654|IRS4_HUMAN,tr|A0A804CF45|A0A804CF45_HUMAN" 2 1144.528 0.82 48636 14677 2 1144.524118 573.2713 Insulin receptor substrate 4 OS=Homo sapiens OX=9606 GN=IRS4 PE=1 SV=1 4.37 2691.1 - 1.65E+06 - - - -3.4259 - 1.353 0.387 - 163.8 1 2 0 -0.0039 9 0 0 0 1.12E+07 1.36E+07 - - - 2.7728 1 221125_WJC_METTL3_EV_vs_WT_F04.14679.14679.2 2.29E-09 14/24 K.STNPGISIGDVAK[136.11].K "sp|O15347|HMGB3_HUMAN,tr|E9PES6|E9PES6_HUMAN,tr|E7EQU1|E7EQU1_HUMAN,tr|E7ES08|E7ES08_HUMAN" 4 1265.6707 0.16 48638 14679 2 1265.671175 633.8426 High mobility group protein B3 OS=Homo sapiens OX=9606 GN=HMGB3 PE=1 SV=4 5.55 2691.3 - 1.18E+06 - - - 0.3903 - 2.743 0.597 - 735.9 1 2 0 0.0005 13 0 0 0 9.39E+06 5.92E+07 - - - 6.04 0.9999 221125_WJC_METTL3_EV_vs_WT_F04.14680.14680.2 0.000422 13/22 K.GSGNLEAIHIIK[136.11].K "sp|P78371|TCPB_HUMAN,tr|F8VQ14|F8VQ14_HUMAN,tr|F5GWF6|F5GWF6_HUMAN" 3 1258.7125 0.55 48639 14680 2 1258.712046 630.3635 T-complex protein 1 subunit beta OS=Homo sapiens OX=9606 GN=CCT2 PE=1 SV=4 6.75 2691.4 - 1.13E+06 - - - -0.3496 - 2.69 0.468 - 867.1 1 2 0 -0.0004 12 0 0 0 2.14E+07 3.90E+07 - - - 5.1012 1 221125_WJC_METTL3_EV_vs_WT_F04.14681.14681.3 1.67E-05 16/36 R.SIHDALC[160.03]VIR.C "sp|P50991|TCPD_HUMAN,sp|P48643|TCPE_HUMAN,tr|E9PCA1|E9PCA1_HUMAN,tr|B7ZAR1|B7ZAR1_HUMAN,tr|E7ENZ3|E7ENZ3_HUMAN" 5 1182.6179 0.32 48640 14681 3 1182.618578 395.2133 T-complex protein 1 subunit delta OS=Homo sapiens OX=9606 GN=CCT4 PE=1 SV=4 6.46 2691.5 - 1.09E+06 - - - 0.5505 - 2.66 0.495 - 433.2 1 2 0 0.0007 10 0 0 0 3.14E+07 9.84E+07 - - - 6.9157 1 221125_WJC_METTL3_EV_vs_WT_F04.14682.14682.3 1.40E-06 Nov-52 R.GYAFNHSADFETVR.M "sp|P61160|ARP2_HUMAN,tr|F5H6T1|F5H6T1_HUMAN" 2 1612.727 1.76 48641 14682 3 1612.726491 538.5829 Actin-related protein 2 OS=Homo sapiens OX=9606 GN=ACTR2 PE=1 SV=1 5.32 2691.5 - 810152 - - - -0.328 - 2.305 0.542 - 104.1 1 2 0 -0.0005 14 0 0 0 4.99E+06 2.83E+06 - - - 6.8019 0.9998 221125_WJC_METTL3_EV_vs_WT_F04.14683.14683.2 0.000891 14-Sep K.FEMEQNLR.Q "sp|P35527|K1C9_HUMAN,tr|K7EQQ3|K7EQQ3_HUMAN" 2 1065.4913 204.67 48642 14683 2 1065.492587 533.7529 "Keratin, type I cytoskeletal 9 OS=Homo sapiens OX=9606 GN=KRT9 PE=1 SV=3" 4.53 2691.7 - 737667 - - - 1.1797 - 1.771 0.539 - 285.7 1 2 0 0.0013 8 0 0 0 1.08E+07 5.28E+04 - - - 4.7454 0.9999 221125_WJC_METTL3_EV_vs_WT_F04.14685.14685.3 6.25E-07 16/56 K.ILTGGADKNVVVFDK.S sp|Q9UMS4|PRP19_HUMAN 1 1574.8668 1.16 48644 14685 3 1574.867794 525.9629 Pre-mRNA-processing factor 19 OS=Homo sapiens OX=9606 GN=PRPF19 PE=1 SV=1 5.96 2691.9 - 524999 - - - 0.6261 - 2.931 0.471 - 264.7 1 2 1 0.001 15 0 0 0 3.79E+07 3.26E+07 - - - 6.5969 1 221125_WJC_METTL3_EV_vs_WT_F04.14686.14686.3 0.00126 14/52 K.HTLVEADIGIQAER[166.11].V "sp|Q01082|SPTB2_HUMAN,tr|A0A087WUZ3|A0A087WUZ3_HUMAN,tr|F8W6C1|F8W6C1_HUMAN" 3 1560.8135 3.84 48645 14686 3 1560.816915 521.2785 "Spectrin beta chain, non-erythrocytic 1 OS=Homo sapiens OX=9606 GN=SPTBN1 PE=1 SV=2" 4.65 2692.1 - 504207 - - - 2.1623 - 2.989 0.501 - 389.1 1 2 0 0.0034 14 0 0 0 6.45E+06 1.68E+06 - - - 7.0346 1 221125_WJC_METTL3_EV_vs_WT_F04.14689.14689.2 7.22E-10 14/32 N.IVSNASC[160.03]TTNC[160.03]LAPLAK.V "sp|O14556|G3PT_HUMAN,tr|K7EP73|K7EP73_HUMAN" 2 1818.8968 999 48648 14689 2 1818.902494 910.4557 "Glyceraldehyde-3-phosphate dehydrogenase, testis-specific OS=Homo sapiens OX=9606 GN=GAPDHS PE=1 SV=2" 8.06 2692.4 - 149529 - - - 3.1277 - 2.818 0.587 - 391.9 1 1 0 0.0057 17 0 0 0 2.21E+06 0.00E+00 - - - 5.9219 0.9998 221125_WJC_METTL3_EV_vs_WT_F04.14695.14695.2 0.000319 22-Oct K.GSGNLEAIHIIK.K "sp|P78371|TCPB_HUMAN,tr|F8VQ14|F8VQ14_HUMAN,tr|F5GWF6|F5GWF6_HUMAN" 3 1250.6983 0.55 48653 14695 2 1250.69681 626.3564 T-complex protein 1 subunit beta OS=Homo sapiens OX=9606 GN=CCT2 PE=1 SV=4 6.75 2693 - 1.37E+06 - - - -1.1801 - 2.274 0.43 - 336.3 1 2 0 -0.0015 12 0 0 0 2.14E+07 3.90E+07 - - - 4.3781 0.9844 221125_WJC_METTL3_EV_vs_WT_F04.14696.14696.2 0.14 13/18 S.GNLEAIHIIK[136.11].K "sp|P78371|TCPB_HUMAN,tr|F8VQ14|F8VQ14_HUMAN,tr|F5GWF6|F5GWF6_HUMAN" 3 1114.659 0.59 48654 14696 2 1114.657801 558.3368 T-complex protein 1 subunit beta OS=Homo sapiens OX=9606 GN=CCT2 PE=1 SV=4 6.75 2693.1 - 1.12E+06 - - - -1.0703 - 2.074 0.395 - 605.1 1 1 0 -0.0012 10 0 0 0 8.02E+06 1.37E+07 - - - 3.9943 0.9957 221125_WJC_METTL3_EV_vs_WT_F04.14699.14699.2 0.00305 24-Nov R.SQLQGPSSSEYWK[136.11].E "sp|P39880|CUX1_HUMAN,tr|A0A2R8Y852|A0A2R8Y852_HUMAN,tr|A0A2R8YDI1|A0A2R8YDI1_HUMAN" 3 1503.7085 1.22 48657 14699 2 1503.715994 752.8615 Homeobox protein cut-like 1 OS=Homo sapiens OX=9606 GN=CUX1 PE=1 SV=3 5.72 2693.4 - 590718 - - - 4.9684 - 2.161 0.396 - 228.3 1 2 0 0.0075 13 0 0 0 7.47E+06 6.11E+06 - - - 3.9412 0.9999 221125_WJC_METTL3_EV_vs_WT_F04.14701.14701.3 1.64E-07 14/48 K.FNEC[160.03]GHVLYADIK.M "sp|P52272|HNRPM_HUMAN,tr|A0A087X0X3|A0A087X0X3_HUMAN" 2 1564.7344 1.5 48659 14701 3 1564.740277 522.5854 Heterogeneous nuclear ribonucleoprotein M OS=Homo sapiens OX=9606 GN=HNRNPM PE=1 SV=3 5.32 2693.7 - 480570 - - - 3.747 - 2.361 0.577 - 129.1 1 2 0 0.0059 13 0 0 0 6.24E+07 4.16E+07 - - - 7.3006 0.9997 221125_WJC_METTL3_EV_vs_WT_F04.14704.14704.2 5.06E-06 22-Oct R.ENPLLPEEEEQR.A "sp|P78344|IF4G2_HUMAN,tr|H0YEC5|H0YEC5_HUMAN,tr|H0Y3P2|H0Y3P2_HUMAN,tr|H0YCH5|H0YCH5_HUMAN,tr|H0YD77|H0YD77_HUMAN,tr|D3DQV9|D3DQV9_HUMAN" 6 1481.6998 3.76 48661 14704 2 1481.698091 741.8572 Eukaryotic translation initiation factor 4 gamma 2 OS=Homo sapiens OX=9606 GN=EIF4G2 PE=1 SV=1 3.98 2694 - 2.28E+06 - - - -1.1548 - 2.404 0.353 - 186.3 1 2 0 -0.0017 12 0 0 0 1.43E+07 3.82E+06 - - - 3.9556 0.9965 221125_WJC_METTL3_EV_vs_WT_F04.14705.14705.2 0.0654 20-Jul K.GEDFPANNIVK.F "sp|P43307|SSRA_HUMAN,tr|A0A3B3IRT8|A0A3B3IRT8_HUMAN,tr|E9PAL7|E9PAL7_HUMAN,tr|C9IZQ1|C9IZQ1_HUMAN,tr|C9J3L8|C9J3L8_HUMAN,tr|C9J5W0|C9J5W0_HUMAN" 6 1202.5932 1.1 48662 14705 2 1202.591122 602.3039 Translocon-associated protein subunit alpha OS=Homo sapiens OX=9606 GN=SSR1 PE=1 SV=3 4.37 2694.1 - 0 - - - -1.688 - 1.322 0.27 - 147.1 1 2 0 -0.002 11 0 0 0 1.92E+07 1.75E+07 - - - 1.7897 0.9999 221125_WJC_METTL3_EV_vs_WT_F04.14706.14706.3 9.21E-06 Dec-44 K.FMDQHPEMDFSK.A sp|Q9Y266|NUDC_HUMAN 1 1510.6221 1.61 48663 14706 3 1510.620239 504.548 Nuclear migration protein nudC OS=Homo sapiens OX=9606 GN=NUDC PE=1 SV=1 4.54 2694.2 - 7.34E+06 - - - -1.2227 - 1.988 0.5 - 104.2 1 2 0 -0.0018 12 0 0 0 7.46E+07 4.63E+07 - - - 6.0186 1 221125_WJC_METTL3_EV_vs_WT_F04.14707.14707.3 9.79E-05 16/68 K.YVHYEIDAC[160.03]MDSEAPGSK[136.11].D "sp|Q86U44|MTA70_HUMAN,tr|H0YFV6|H0YFV6_HUMAN" 2 2078.8805 0.16 48664 14707 3 2078.87674 693.9674 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 4.31 2694.3 - 2.21E+06 - - - -1.8048 - 3.339 0.581 - 230.8 1 2 0 -0.0038 18 0 0 0 2.42E+06 1.54E+07 - - - 8.0188 0.9997 221125_WJC_METTL3_EV_vs_WT_F04.14709.14709.2 8.73E-05 24-Dec K.LFIVESNSSSSTR.S sp|P48507|GSH0_HUMAN 1 1425.71 1.94 48666 14709 2 1425.70673 713.8623 Glutamate--cysteine ligase regulatory subunit OS=Homo sapiens OX=9606 GN=GCLM PE=1 SV=1 6 2694.4 - 1.72E+06 - - - -2.2747 - 2.446 0.486 - 379.7 1 2 0 -0.0032 13 0 0 0 2.64E+07 1.36E+07 - - - 4.9252 0.9998 221125_WJC_METTL3_EV_vs_WT_F04.14712.14712.2 8.69E-05 16-Oct K.DSEDIYNLK.N sp|Q96DG6|CMBL_HUMAN 1 1095.5084 1.25 48669 14712 2 1095.509363 548.7615 Carboxymethylenebutenolidase homolog OS=Homo sapiens OX=9606 GN=CMBL PE=1 SV=1 4.03 2694.7 - 791337 - - - 0.8608 - 2.055 0.413 - 387.9 1 2 0 0.0009 9 0 0 0 6.10E+06 4.86E+06 - - - 4.1749 0.9999 221125_WJC_METTL3_EV_vs_WT_F04.14716.14716.3 0.0119 13/40 K.IYAMHWGTDSR.L "sp|P62879|GBB2_HUMAN,sp|P62873|GBB1_HUMAN,tr|F6X3N5|F6X3N5_HUMAN,tr|C9JZN1|C9JZN1_HUMAN,tr|F6UT28|F6UT28_HUMAN,tr|C9JIS1|C9JIS1_HUMAN,tr|B1AKQ8|B1AKQ8_HUMAN,tr|E7EP32|E7EP32_HUMAN,tr|C9JXA5|C9JXA5_HUMAN" 9 1335.603 0.64 48673 14716 3 1335.599536 446.2083 Guanine nucleotide-binding protein G(I)\G(S)\G(T) subunit beta-2 OS=Homo sapiens OX=9606 GN=GNB2 PE=1 SV=3 6.74 2695.2 - 700088 - - - -2.5973 - 2.202 0.461 - 243.6 1 2 0 -0.0035 11 0 0 0 7.12E+06 1.11E+07 - - - 5.9212 1 221125_WJC_METTL3_EV_vs_WT_F04.14719.14719.2 0.000325 17/26 R.NQDATVYVGGLDEK.V sp|Q15427|SF3B4_HUMAN 1 1507.7155 0.73 48676 14719 2 1507.71313 754.865 Splicing factor 3B subunit 4 OS=Homo sapiens OX=9606 GN=SF3B4 PE=1 SV=1 4.03 2695.6 - 505240 - - - -1.5401 - 3.448 0.613 - 1355.6 1 2 0 -0.0023 14 0 0 0 1.05E+07 1.44E+07 - - - 6.6741 0.9998 221125_WJC_METTL3_EV_vs_WT_F04.14726.14726.2 0.00352 24-Oct K.LFIVESNSSSSTR[166.11].S sp|P48507|GSH0_HUMAN 1 1435.7182 1.88 48681 14726 2 1435.716767 718.8664 Glutamate--cysteine ligase regulatory subunit OS=Homo sapiens OX=9606 GN=GCLM PE=1 SV=1 6 2696.3 - 1.87E+06 - - - -1.0281 - 2.163 0.448 - 268.1 1 2 0 -0.0015 13 0 0 0 2.56E+07 1.37E+07 - - - 4.3295 0.9991 221125_WJC_METTL3_EV_vs_WT_F04.14727.14727.2 0.000118 18-Oct K.YEELQVTVGR.H sp|P35908|K22E_HUMAN 1 1192.6088 2.57 48682 14727 2 1192.613106 597.3117 "Keratin, type II cytoskeletal 2 epidermal OS=Homo sapiens OX=9606 GN=KRT2 PE=1 SV=2" 4.53 2696.4 - 6.58E+06 - - - 3.6089 - 2.089 0.488 - 415.2 1 2 0 0.0043 10 0 0 0 4.23E+07 1.65E+07 - - - 4.7003 1 221125_WJC_METTL3_EV_vs_WT_F04.14730.14730.2 1.46E-06 16/20 K.HGEIDYEAIVK[136.11].L "sp|P62333|PRS10_HUMAN,tr|A0A087X2I1|A0A087X2I1_HUMAN" 2 1280.6492 0.74 48685 14730 2 1280.6463 641.3319 26S proteasome regulatory subunit 10B OS=Homo sapiens OX=9606 GN=PSMC6 PE=1 SV=1 4.65 2696.6 - 1.34E+06 - - - -2.2778 - 3.022 0.539 - 578.8 1 2 0 -0.0029 11 0 0 0 7.20E+06 9.71E+06 - - - 6.0129 0.9988 221125_WJC_METTL3_EV_vs_WT_F04.14732.14732.3 0.0185 Nov-44 K.IQGDDWEPR[166.11]PLR[166.11].A "sp|O95817|BAG3_HUMAN,tr|C9JFK9|C9JFK9_HUMAN" 2 1500.7588 0.28 48687 14732 3 1500.758475 501.2602 BAG family molecular chaperone regulator 3 OS=Homo sapiens OX=9606 GN=BAG3 PE=1 SV=3 4.56 2696.8 - 718390 - - - -0.2272 - 1.761 0.275 - 145.6 1 2 0 -0.0003 12 0 0 0 1.80E+06 6.39E+06 - - - 3.1744 0.9894 221125_WJC_METTL3_EV_vs_WT_F04.14733.14733.2 5.91E-06 28-Oct K.ILTGGADKNVVVFDK.S sp|Q9UMS4|PRP19_HUMAN 1 1574.8668 2.27 48688 14733 2 1574.860879 788.4407 Pre-mRNA-processing factor 19 OS=Homo sapiens OX=9606 GN=PRPF19 PE=1 SV=1 5.96 2696.9 - 437050 - - - -3.7648 - 2.304 0.508 - 248.7 1 2 1 -0.0059 15 0 0 0 2.32E+06 1.02E+06 - - - 4.8432 0.9996 221125_WJC_METTL3_EV_vs_WT_F04.14737.14737.2 0.00478 18-Dec R.SIHDALC[160.03]VIR.C "sp|P50991|TCPD_HUMAN,sp|P48643|TCPE_HUMAN,tr|E9PCA1|E9PCA1_HUMAN,tr|B7ZAR1|B7ZAR1_HUMAN,tr|E7ENZ3|E7ENZ3_HUMAN" 5 1182.6179 0.73 48691 14737 2 1182.616549 592.3162 T-complex protein 1 subunit delta OS=Homo sapiens OX=9606 GN=CCT4 PE=1 SV=4 6.46 2697.4 - 1.23E+06 - - - -1.1652 - 1.866 0.379 - 477.5 1 2 0 -0.0014 10 0 0 0 6.87E+06 9.43E+06 - - - 3.5811 0.9999 221125_WJC_METTL3_EV_vs_WT_F04.14738.14738.2 2.39E-06 13/24 K.YTDLNSNDVTGLR.E "sp|Q15007|FL2D_HUMAN,tr|A0A087X1R4|A0A087X1R4_HUMAN" 2 1466.7001 0.93 48692 14738 2 1466.698608 734.3573 Pre-mRNA-splicing regulator WTAP OS=Homo sapiens OX=9606 GN=WTAP PE=1 SV=2 4.21 2697.5 - 2.72E+06 - - - -1.0425 - 2.654 0.562 - 576.7 1 2 0 -0.0015 13 0 0 0 2.43E+07 2.60E+07 - - - 5.6966 1 221125_WJC_METTL3_EV_vs_WT_F04.14739.14739.3 2.68E-06 15/44 R.VVDLMAHMASK[136.11]E.- "sp|P04406|G3P_HUMAN,tr|E7EUT5|E7EUT5_HUMAN" 2 1337.6563 1.23 48693 14739 3 1337.654332 446.8927 Glyceraldehyde-3-phosphate dehydrogenase OS=Homo sapiens OX=9606 GN=GAPDH PE=1 SV=3 5.51 2697.5 - 1.66E+06 - - - -1.466 - 2.507 0.55 - 265.4 1 2 0 -0.002 12 0 0 0 1.25E+08 1.02E+08 - - - 7.219 1 221125_WJC_METTL3_EV_vs_WT_F04.14740.14740.2 1.55E-06 17/26 R.NQDATVYVGGLDEK[136.11].V sp|Q15427|SF3B4_HUMAN 1 1515.7297 0.73 48694 14740 2 1515.728685 758.8721 Splicing factor 3B subunit 4 OS=Homo sapiens OX=9606 GN=SF3B4 PE=1 SV=1 4.03 2697.7 - 1.61E+06 - - - -0.638 - 3.422 0.642 - 1344.2 1 2 0 -0.001 14 0 0 0 1.05E+07 1.44E+07 - - - 6.8697 1 221125_WJC_METTL3_EV_vs_WT_F04.14741.14741.3 0.000491 Oct-40 K.HGEIDYEAIVK[136.11].L "sp|P62333|PRS10_HUMAN,tr|A0A087X2I1|A0A087X2I1_HUMAN" 2 1280.6492 0.65 48695 14741 3 1280.649336 427.8903 26S proteasome regulatory subunit 10B OS=Homo sapiens OX=9606 GN=PSMC6 PE=1 SV=1 4.65 2697.8 - 1.06E+06 - - - 0.0929 - 1.985 0.553 - 171.5 1 2 0 0.0001 11 0 0 0 7.48E+06 1.16E+07 - - - 6.6531 0.9905 221125_WJC_METTL3_EV_vs_WT_F04.14743.14743.2 9.42E-05 14/26 R.AIYDTPC[160.03]IQAESEK.W sp|O00232|PSD12_HUMAN 1 1623.745 0.43 48697 14743 2 1623.733222 812.8798 26S proteasome non-ATPase regulatory subunit 12 OS=Homo sapiens OX=9606 GN=PSMD12 PE=1 SV=3 4.14 2698 - 822855 - - - -7.277 - 2.543 0.503 - 531.2 1 2 0 -0.0118 14 0 0 0 1.92E+06 4.50E+06 - - - 5.0946 0.9505 221125_WJC_METTL3_EV_vs_WT_F04.14744.14744.3 0.901 Oct-32 K.FVEIHFNEK[136.11].S "sp|Q9UM54|MYO6_HUMAN,tr|A0A590UK86|A0A590UK86_HUMAN,tr|A0A590UK71|A0A590UK71_HUMAN,tr|A0A0D9SGC1|A0A0D9SGC1_HUMAN,tr|A0A0A0MRM8|A0A0A0MRM8_HUMAN,tr|A0A5F9ZI03|A0A5F9ZI03_HUMAN,tr|A0A590UK22|A0A590UK22_HUMAN,tr|A0A590UJY4|A0A590UJY4_HUMAN,tr|A0A590UJ40|A0A590UJ40_HUMAN,tr|A0A590UJ75|A0A590UJ75_HUMAN,tr|E7EW20|E7EW20_HUMAN,tr|A0A590UKB0|A0A590UKB0_HUMAN,tr|A0A1Y0BRN3|A0A1Y0BRN3_HUMAN" 13 1169.5961 1.01 48698 14744 3 1169.594148 390.8726 Unconventional myosin-VI OS=Homo sapiens OX=9606 GN=MYO6 PE=1 SV=4 5.4 2698.1 - 715092 - - - -1.6339 - 1.562 0.105 - 88.1 1 2 0 -0.0019 9 0 0 0 4.53E+06 4.50E+06 - - - 1.0542 0.9862 221125_WJC_METTL3_EV_vs_WT_F04.14746.14746.2 8.95E-05 26-Oct R.AIYDTPC[160.03]IQAESEK[136.11].W sp|O00232|PSD12_HUMAN 1 1631.7592 0.43 48700 14746 2 1631.748038 816.8869 26S proteasome non-ATPase regulatory subunit 12 OS=Homo sapiens OX=9606 GN=PSMD12 PE=1 SV=3 4.14 2698.4 - 683158 - - - -6.8638 - 2.022 0.443 - 232.6 1 2 0 -0.0112 14 0 0 0 1.92E+06 4.50E+06 - - - 4.0764 0.9998 221125_WJC_METTL3_EV_vs_WT_F04.14749.14749.2 0.00414 20-Nov K.QSGESIDIITR[166.11].A "sp|Q16531|DDB1_HUMAN,tr|F5GWI0|F5GWI0_HUMAN,tr|F5H2L3|F5H2L3_HUMAN,tr|A0A7P0TAK7|A0A7P0TAK7_HUMAN,tr|A0A7P0T870|A0A7P0T870_HUMAN,tr|A0A7P0Z3Z5|A0A7P0Z3Z5_HUMAN,tr|F5GZY8|F5GZY8_HUMAN,tr|F5GY55|F5GY55_HUMAN,tr|A0A7P0Z4B9|A0A7P0Z4B9_HUMAN,tr|A0A7P0Z4L2|A0A7P0Z4L2_HUMAN,tr|A0A7P0T965|A0A7P0T965_HUMAN" 11 1227.6335 0.57 48703 14749 2 1227.633632 614.824 DNA damage-binding protein 1 OS=Homo sapiens OX=9606 GN=DDB1 PE=1 SV=1 4.37 2698.8 - 296999 - - - 0.1474 - 2.415 0.361 - 587 1 2 0 0.0002 11 0 0 0 7.12E+06 1.25E+07 - - - 4.0925 1 221125_WJC_METTL3_EV_vs_WT_F04.14752.14752.3 9.46E-06 Oct-48 K.FNEC[160.03]GHVLYADIK[136.11].M "sp|P52272|HNRPM_HUMAN,tr|A0A087X0X3|A0A087X0X3_HUMAN" 2 1572.7486 1.5 48704 14752 3 1572.74754 525.2568 Heterogeneous nuclear ribonucleoprotein M OS=Homo sapiens OX=9606 GN=HNRNPM PE=1 SV=3 5.32 2699.2 - 5.84E+06 - - - -0.6829 - 1.83 0.53 - 69.2 1 2 0 -0.0011 13 0 0 0 6.24E+07 4.16E+07 - - - 6.0872 1 221125_WJC_METTL3_EV_vs_WT_F04.14753.14753.2 9.71E-09 24-Dec K.YTDLNSNDVTGLR[166.11].E "sp|Q15007|FL2D_HUMAN,tr|A0A087X1R4|A0A087X1R4_HUMAN" 2 1476.7084 0.93 48705 14753 2 1476.707075 739.3615 Pre-mRNA-splicing regulator WTAP OS=Homo sapiens OX=9606 GN=WTAP PE=1 SV=2 4.21 2699.2 - 3.19E+06 - - - -0.902 - 2.521 0.682 - 479.4 1 2 0 -0.0013 13 0 0 0 2.43E+07 2.60E+07 - - - 6.451 0.9998 221125_WJC_METTL3_EV_vs_WT_F04.14754.14754.3 9.22E-06 14/60 K.VMATTGGTNLR[166.11]DDIMR[166.11].L sp|P26196|DDX6_HUMAN 1 1769.8667 1.31 48706 14754 3 1769.866598 590.9629 Probable ATP-dependent RNA helicase DDX6 OS=Homo sapiens OX=9606 GN=DDX6 PE=1 SV=2 5.93 2699.3 - 2.59E+06 - - - -0.0735 - 2.326 0.509 - 233.2 1 2 1 -0.0001 16 0 0 0 2.97E+07 2.26E+07 - - - 6.3808 0.9997 221125_WJC_METTL3_EV_vs_WT_F04.14756.14756.3 0.00526 Nov-36 K.DLEIQALHAR.L "sp|Q15643|TRIPB_HUMAN,tr|H0YJ97|H0YJ97_HUMAN" 2 1164.6251 1.19 48708 14756 3 1164.624901 389.2157 Thyroid receptor-interacting protein 11 OS=Homo sapiens OX=9606 GN=TRIP11 PE=1 SV=3 5.32 2699.4 - 1.38E+06 - - - -0.1889 - 1.913 0.337 - 162.1 1 2 0 -0.0002 10 0 0 0 3.50E+07 2.94E+07 - - - 4.1916 0.9986 221125_WJC_METTL3_EV_vs_WT_F04.14757.14757.3 0.0202 Dec-36 K.DLEIQALHAR[166.11].L "sp|Q15643|TRIPB_HUMAN,tr|H0YJ97|H0YJ97_HUMAN" 2 1174.6334 1.19 48709 14757 3 1174.6335 392.5517 Thyroid receptor-interacting protein 11 OS=Homo sapiens OX=9606 GN=TRIP11 PE=1 SV=3 5.32 2699.5 - 1.30E+06 - - - 0.0928 - 1.921 0.237 - 179 1 2 0 0.0001 10 0 0 0 3.49E+07 2.94E+07 - - - 3.0889 1 221125_WJC_METTL3_EV_vs_WT_F04.14759.14759.3 0.0104 Nov-40 R.DQFNSHIQLVR.N "sp|Q8ND24|RN214_HUMAN,tr|E9PN76|E9PN76_HUMAN" 2 1355.6946 1.6 48711 14759 3 1355.692873 452.9055 RING finger protein 214 OS=Homo sapiens OX=9606 GN=RNF214 PE=1 SV=2 6.74 2699.7 - 1.13E+06 - - - -1.2724 - 2.386 0.453 - 235.3 1 2 0 -0.0017 11 0 0 0 7.72E+06 4.82E+06 - - - 6.0605 0.9999 221125_WJC_METTL3_EV_vs_WT_F04.14760.14760.3 0.000384 Dec-32 K.DYAFVHMEK.E sp|Q96PK6|RBM14_HUMAN 1 1138.5117 1.8 48712 14760 3 1138.510292 380.5112 RNA-binding protein 14 OS=Homo sapiens OX=9606 GN=RBM14 PE=1 SV=2 5.32 2699.8 - 1.03E+06 - - - -1.2639 - 2.013 0.479 - 239.1 1 2 0 -0.0014 9 0 0 0 1.34E+08 7.46E+07 - - - 5.9885 1 221125_WJC_METTL3_EV_vs_WT_F04.14761.14761.3 0.00032 14/32 K.DYAFVHMEK[136.11].E sp|Q96PK6|RBM14_HUMAN 1 1146.5259 1.75 48713 14761 3 1146.525727 383.1826 RNA-binding protein 14 OS=Homo sapiens OX=9606 GN=RBM14 PE=1 SV=2 5.32 2699.9 - 708032 - - - -0.1779 - 2.025 0.472 - 314.6 1 2 0 -0.0002 9 0 0 0 1.31E+08 7.46E+07 - - - 5.9287 0.9995 221125_WJC_METTL3_EV_vs_WT_F04.14762.14762.3 2.88E-06 13/52 R.YFDR[166.11]VDENNPEYLR[166.11].E "sp|P35611|ADDA_HUMAN,tr|E7EV99|E7EV99_HUMAN,tr|E7ENY0|E7ENY0_HUMAN,tr|A0A804HL01|A0A804HL01_HUMAN,tr|A0A0A0MSR2|A0A0A0MSR2_HUMAN,tr|D6RAH3|D6RAH3_HUMAN,tr|D6RF25|D6RF25_HUMAN,tr|D6RJE2|D6RJE2_HUMAN" 8 1848.8546 0.49 48714 14762 3 1848.854375 617.2921 Alpha-adducin OS=Homo sapiens OX=9606 GN=ADD1 PE=1 SV=2 4.32 2700.1 - 602772 - - - -0.1038 - 2.248 0.397 - 221.2 1 2 1 -0.0002 14 0 0 0 1.32E+06 2.70E+06 - - - 5.1188 0.9999 221125_WJC_METTL3_EV_vs_WT_F04.14763.14763.2 7.02E-06 13/20 K.HGEIDYEAIVK.L "sp|P62333|PRS10_HUMAN,tr|A0A087X2I1|A0A087X2I1_HUMAN" 2 1272.635 0.74 48715 14763 2 1272.634757 637.3248 26S proteasome regulatory subunit 10B OS=Homo sapiens OX=9606 GN=PSMC6 PE=1 SV=1 4.65 2700.2 - 571720 - - - -0.2043 - 2.439 0.537 - 595.2 1 2 0 -0.0003 11 0 0 0 7.11E+06 9.66E+06 - - - 5.4192 1 221125_WJC_METTL3_EV_vs_WT_F04.14764.14764.2 7.88E-05 14/22 R.VVDLMAHMASK[136.11]E.- "sp|P04406|G3P_HUMAN,tr|E7EUT5|E7EUT5_HUMAN" 2 1337.6563 5.47 48716 14764 2 1337.652613 669.8354 Glyceraldehyde-3-phosphate dehydrogenase OS=Homo sapiens OX=9606 GN=GAPDH PE=1 SV=3 5.51 2700.3 - 540052 - - - -2.7511 - 2.755 0.55 - 498 1 2 0 -0.0037 12 0 0 0 6.63E+07 1.21E+07 - - - 5.7686 0.9997 221125_WJC_METTL3_EV_vs_WT_F04.14765.14765.2 7.85E-06 22-Nov R.ELISNASDALEK.L sp|Q12931|TRAP1_HUMAN 1 1288.6511 0.29 48717 14765 2 1288.648097 645.3328 "Heat shock protein 75 kDa, mitochondrial OS=Homo sapiens OX=9606 GN=TRAP1 PE=1 SV=3" 4.14 2700.5 - 462016 - - - -2.3001 - 2.341 0.492 - 434.6 1 2 0 -0.003 12 0 0 0 3.55E+06 1.21E+07 - - - 4.912 0.9998 221125_WJC_METTL3_EV_vs_WT_F04.14766.14766.2 1.93E-06 13/24 R.C[160.03]LSLSAGQTTLSR[166.11].E sp|Q9BTE3|MCMBP_HUMAN 1 1402.7114 0.25 48718 14766 2 1402.713215 702.363 Mini-chromosome maintenance complex-binding protein OS=Homo sapiens OX=9606 GN=MCMBP PE=1 SV=2 8.25 2700.6 - 383464 - - - 1.3053 - 2.334 0.482 - 507.2 1 2 0 0.0018 13 0 0 0 5.07E+05 2.05E+06 - - - 4.7758 0.9999 221125_WJC_METTL3_EV_vs_WT_F04.14767.14767.2 5.58E-07 13/24 K.FNEC[160.03]GHVLYADIK[136.11].M "sp|P52272|HNRPM_HUMAN,tr|A0A087X0X3|A0A087X0X3_HUMAN" 2 1572.7486 -1 48719 14767 2 1572.745885 787.3816 Heterogeneous nuclear ribonucleoprotein M OS=Homo sapiens OX=9606 GN=HNRNPM PE=1 SV=3 5.32 2700.7 - 347883 - - - -1.7352 - 3.091 0.509 - 556.1 1 2 0 -0.0027 13 0 0 0 0.00E+00 0.00E+00 - - - 5.6959 1 221125_WJC_METTL3_EV_vs_WT_F04.14773.14773.3 2.44E-06 24/64 K.LQALANEQAAAAHELEK.M sp|Q86UP2|KTN1_HUMAN 1 1805.9272 2.08 48724 14773 3 1805.924727 602.983 Kinectin OS=Homo sapiens OX=9606 GN=KTN1 PE=1 SV=1 4.75 2701.5 - 2.46E+06 - - - -1.3561 - 3.895 0.572 - 768.8 1 2 0 -0.0024 17 0 0 0 1.87E+07 9.01E+06 - - - 8.3516 0.9999 221125_WJC_METTL3_EV_vs_WT_F04.14775.14775.3 0.0246 Dec-40 K.YNPTWHC[160.03]IVGR.N "sp|Q96FJ2|DYL2_HUMAN,sp|P63167|DYL1_HUMAN" 2 1401.6612 1.12 48726 14775 3 1401.661104 468.2277 "Dynein light chain 2, cytoplasmic OS=Homo sapiens OX=9606 GN=DYNLL2 PE=1 SV=1" 8.23 2701.6 - 2.70E+06 - - - -0.0606 - 2.275 0.38 - 190 1 2 0 -0.0001 11 0 0 0 5.30E+07 4.73E+07 - - - 5.1117 1 221125_WJC_METTL3_EV_vs_WT_F04.14776.14776.3 8.53E-07 15/40 K.YNPTWHC[160.03]IVGR[166.11].N "sp|Q96FJ2|DYL2_HUMAN,sp|P63167|DYL1_HUMAN" 2 1411.6695 1.24 48727 14776 3 1411.670609 471.5638 "Dynein light chain 2, cytoplasmic OS=Homo sapiens OX=9606 GN=DYNLL2 PE=1 SV=1" 8.23 2701.6 - 2.62E+06 - - - 0.8146 - 2.632 0.548 - 348.1 1 2 0 0.0011 11 0 0 0 8.83E+07 7.13E+07 - - - 7.3985 0.9999 221125_WJC_METTL3_EV_vs_WT_F04.14777.14777.3 6.75E-08 16/56 R.LLIVSTTPYSEK[136.11]DTK[136.11].Q "sp|Q9Y230|RUVB2_HUMAN,tr|M0R0Y3|M0R0Y3_HUMAN" 2 1709.9422 0.8 48728 14777 3 1709.943698 570.988 RuvB-like 2 OS=Homo sapiens OX=9606 GN=RUVBL2 PE=1 SV=3 6.07 2701.7 - 1.66E+06 - - - 0.8655 - 2.567 0.634 - 259.1 1 2 1 0.0015 15 0 0 0 1.25E+07 1.56E+07 - - - 8.068 1 221125_WJC_METTL3_EV_vs_WT_F04.14778.14778.3 5.43E-06 Dec-44 K.FMDQHPEMDFSK[136.11].A sp|Q9Y266|NUDC_HUMAN 1 1518.6363 1.6 48729 14778 3 1518.636523 507.2194 Nuclear migration protein nudC OS=Homo sapiens OX=9606 GN=NUDC PE=1 SV=1 4.54 2701.8 - 1.55E+06 - - - 0.1561 - 2.226 0.671 - 109.4 1 2 0 0.0002 12 0 0 0 7.43E+07 4.63E+07 - - - 8.239 0.9999 221125_WJC_METTL3_EV_vs_WT_F04.14779.14779.2 2.56E-05 22-Nov R.MGGGSIEVSVPR.F sp|Q96I24|FUBP3_HUMAN 1 1187.5969 1.42 48730 14779 2 1187.597526 594.8057 Far upstream element-binding protein 3 OS=Homo sapiens OX=9606 GN=FUBP3 PE=1 SV=2 5.75 2701.9 - 1.51E+06 - - - 0.5633 - 2.746 0.543 - 493 1 2 0 0.0007 12 0 0 0 1.34E+07 9.44E+06 - - - 5.7093 0.9999 221125_WJC_METTL3_EV_vs_WT_F04.14780.14780.3 9.81E-05 Nov-52 R.WDDEPHISASVAVK.Q "sp|Q14966|ZN638_HUMAN,tr|C9JWN0|C9JWN0_HUMAN" 2 1552.7522 1 48731 14780 3 1552.752791 518.5913 Zinc finger protein 638 OS=Homo sapiens OX=9606 GN=ZNF638 PE=1 SV=2 4.54 2701.9 - 1.24E+06 - - - 0.3986 - 1.898 0.462 - 122.5 1 2 0 0.0006 14 0 0 0 7.25E+06 7.26E+06 - - - 5.3936 0.9999 221125_WJC_METTL3_EV_vs_WT_F04.14781.14781.3 3.11E-08 Dec-56 R.LLIVSTTPYSEKDTK.Q "sp|Q9Y230|RUVB2_HUMAN,tr|M0R0Y3|M0R0Y3_HUMAN" 2 1693.9138 0.8 48732 14781 3 1693.914689 565.6452 RuvB-like 2 OS=Homo sapiens OX=9606 GN=RUVBL2 PE=1 SV=3 6.07 2702 - 1.24E+06 - - - 0.5142 - 2.571 0.568 - 144.7 1 2 1 0.0009 15 0 0 0 1.25E+07 1.56E+07 - - - 7.3364 1 221125_WJC_METTL3_EV_vs_WT_F04.14783.14783.2 9.69E-07 14/22 R.MGGGSIEVSVPR[166.11].F sp|Q96I24|FUBP3_HUMAN 1 1197.6051 1.02 48734 14783 2 1197.605398 599.8098 Far upstream element-binding protein 3 OS=Homo sapiens OX=9606 GN=FUBP3 PE=1 SV=2 5.75 2702.2 - 906348 - - - 0.2263 - 3.019 0.624 - 863.2 1 2 0 0.0003 12 0 0 0 5.39E+06 5.30E+06 - - - 6.557 0.9858 221125_WJC_METTL3_EV_vs_WT_F04.14786.14786.3 0.0247 Oct-40 K.IRLENEIQTYR.S "sp|P13645|K1C10_HUMAN,tr|A0A1B0GVI3|A0A1B0GVI3_HUMAN" 2 1433.7627 999 48737 14786 3 1433.766549 478.9282 "Keratin, type I cytoskeletal 10 OS=Homo sapiens OX=9606 GN=KRT10 PE=1 SV=6" 6.14 2702.5 - 601013 - - - 2.7006 - 1.938 0.259 - 192.9 1 2 1 0.0039 11 0 0 0 1.14E+07 0.00E+00 - - - 3.3062 0.9793 221125_WJC_METTL3_EV_vs_WT_F04.14789.14789.2 1.75E-07 20-Nov V.VDLMAHMASK[136.11]E.- "sp|P04406|G3P_HUMAN,tr|E7EUT5|E7EUT5_HUMAN" 2 1238.5879 0.87 48740 14789 2 1238.590796 620.3012 Glyceraldehyde-3-phosphate dehydrogenase OS=Homo sapiens OX=9606 GN=GAPDH PE=1 SV=3 5.51 2702.9 - 343131 - - - 2.3551 - 2.595 0.44 - 315.8 1 1 0 0.0029 11 0 0 0 3.54E+06 4.05E+06 - - - 4.8696 0.9999 221125_WJC_METTL3_EV_vs_WT_F04.14790.14790.3 7.80E-05 Nov-44 K.IADLGNAC[160.03]WVHK.H "sp|Q96SB4|SRPK1_HUMAN,sp|Q9UPE1|SRPK3_HUMAN,sp|P78362|SRPK2_HUMAN,tr|H7C5L6|H7C5L6_HUMAN,tr|H3BLV9|H3BLV9_HUMAN,tr|A8MPP7|A8MPP7_HUMAN,tr|A8MPY5|A8MPY5_HUMAN,tr|E7ETV6|E7ETV6_HUMAN,tr|H7C521|H7C521_HUMAN" 9 1382.6765 0.88 48741 14790 3 1382.674855 461.8994 SRSF protein kinase 1 OS=Homo sapiens OX=9606 GN=SRPK1 PE=1 SV=2 6.73 2703.1 - 317518 - - - -1.1933 - 1.997 0.454 - 175.3 1 2 0 -0.0016 12 0 0 0 5.52E+06 6.26E+06 - - - 5.5183 0.9953 221125_WJC_METTL3_EV_vs_WT_F04.14795.14795.2 3.80E-06 20-Oct K.ENGLPLEYQEK.L "sp|O75223|GGCT_HUMAN,tr|M0QZK8|M0QZK8_HUMAN" 2 1318.6405 60.69 48745 14795 2 1318.648404 660.3275 Gamma-glutamylcyclotransferase OS=Homo sapiens OX=9606 GN=GGCT PE=1 SV=1 4.25 2703.6 - 2.03E+06 - - - 5.9971 - 1.986 0.534 - 335 1 2 0 0.0079 11 0 0 0 7.60E+06 1.25E+05 - - - 4.8388 0.9999 221125_WJC_METTL3_EV_vs_WT_F04.14796.14796.3 4.54E-05 13/44 K.GSGWLYHSDAIR.T sp|Q13835|PKP1_HUMAN 1 1360.6524 12.83 48746 14796 3 1360.652772 454.5581 Plakophilin-1 OS=Homo sapiens OX=9606 GN=PKP1 PE=1 SV=2 6.74 2703.7 - 2.01E+06 - - - 0.2749 - 2.604 0.417 - 356 1 2 0 0.0004 12 0 0 0 1.06E+07 8.23E+05 - - - 5.8418 0.9999 221125_WJC_METTL3_EV_vs_WT_F04.14797.14797.2 1.92E-07 22-Dec R.GGAEQFMEETER.S sp|Q99832|TCPH_HUMAN 1 1382.5772 0.17 48747 14797 2 1382.5786 692.2959 T-complex protein 1 subunit eta OS=Homo sapiens OX=9606 GN=CCT7 PE=1 SV=2 4.09 2703.8 - 1.28E+06 - - - 0.9808 - 2.679 0.451 - 627.4 1 2 0 0.0014 12 0 0 0 4.29E+07 2.49E+08 - - - 4.9645 1 221125_WJC_METTL3_EV_vs_WT_F04.14798.14798.3 2.11E-05 Dec-44 R.RTTYLVLDEADR.M "sp|P17844|DDX5_HUMAN,tr|A0A7I2V5F5|A0A7I2V5F5_HUMAN,tr|J3KRZ1|J3KRZ1_HUMAN,tr|J3QSF1|J3QSF1_HUMAN,tr|A0A7I2V507|A0A7I2V507_HUMAN,tr|J3KTA4|J3KTA4_HUMAN,tr|A0A0G2JLI4|A0A0G2JLI4_HUMAN,tr|A0A7I2V2S0|A0A7I2V2S0_HUMAN" 8 1450.7416 1.94 48748 14798 3 1450.74135 484.5878 Probable ATP-dependent RNA helicase DDX5 OS=Homo sapiens OX=9606 GN=DDX5 PE=1 SV=1 4.56 2703.9 - 1.20E+06 - - - -0.1772 - 2.603 0.529 - 342.8 1 2 0 -0.0003 12 0 0 0 2.14E+07 1.10E+07 - - - 7.0895 1 221125_WJC_METTL3_EV_vs_WT_F04.14801.14801.3 3.17E-06 13/44 R.R[166.11]TTYLVLDEADR[166.11].M "sp|P17844|DDX5_HUMAN,tr|A0A7I2V5F5|A0A7I2V5F5_HUMAN,tr|J3KRZ1|J3KRZ1_HUMAN,tr|J3QSF1|J3QSF1_HUMAN,tr|A0A7I2V507|A0A7I2V507_HUMAN,tr|J3KTA4|J3KTA4_HUMAN,tr|A0A0G2JLI4|A0A0G2JLI4_HUMAN,tr|A0A7I2V2S0|A0A7I2V2S0_HUMAN" 8 1470.7581 1.94 48751 14801 3 1470.756483 491.26 Probable ATP-dependent RNA helicase DDX5 OS=Homo sapiens OX=9606 GN=DDX5 PE=1 SV=1 4.56 2704.2 - 787743 - - - -1.1314 - 2.836 0.483 - 374.5 1 2 0 -0.0017 12 0 0 0 2.14E+07 1.10E+07 - - - 6.8139 1 221125_WJC_METTL3_EV_vs_WT_F04.14802.14802.2 5.44E-06 15/24 R.GDVGSADIQDLEK.W "sp|Q9Y5M8|SRPRB_HUMAN,tr|H7C4H2|H7C4H2_HUMAN" 2 1345.6361 1.45 48752 14802 2 1345.635124 673.8253 Signal recognition particle receptor subunit beta OS=Homo sapiens OX=9606 GN=SRPRB PE=1 SV=3 3.84 2704.3 - 662125 - - - -0.7543 - 3.22 0.558 - 1098.3 1 2 0 -0.001 13 0 0 0 3.18E+07 2.20E+07 - - - 6.1633 1 221125_WJC_METTL3_EV_vs_WT_F04.14803.14803.2 4.37E-08 14/24 R.GDVGSADIQDLEK[136.11].W "sp|Q9Y5M8|SRPRB_HUMAN,tr|H7C4H2|H7C4H2_HUMAN" 2 1353.6503 1.46 48753 14803 2 1353.653344 677.8324 Signal recognition particle receptor subunit beta OS=Homo sapiens OX=9606 GN=SRPRB PE=1 SV=3 3.84 2704.4 - 534030 - - - 2.2199 - 3.064 0.572 - 865.4 1 2 0 0.003 13 0 0 0 3.24E+07 2.22E+07 - - - 6.1386 0.9994 221125_WJC_METTL3_EV_vs_WT_F04.14804.14804.2 1.40E-06 22-Nov R.DLEAPEVQESYR.Q "sp|P46379|BAG6_HUMAN,tr|A0A7I2V508|A0A7I2V508_HUMAN,tr|A0A7P0MQS5|A0A7P0MQS5_HUMAN,tr|A0A024RCR6|A0A024RCR6_HUMAN,tr|A0A0G2JK23|A0A0G2JK23_HUMAN" 5 1434.6627 1.77 48754 14804 2 1434.65844 718.3386 Large proline-rich protein BAG6 OS=Homo sapiens OX=9606 GN=BAG6 PE=1 SV=2 4 2704.6 - 525540 - - - -2.961 - 2.142 0.478 - 361.8 1 2 0 -0.0042 12 0 0 0 4.91E+06 2.77E+06 - - - 4.5744 0.9998 221125_WJC_METTL3_EV_vs_WT_F04.14805.14805.2 2.10E-06 24-Sep K.DMGTTDSGPYFEK.L "sp|Q9UPQ9|TNR6B_HUMAN,tr|H0Y720|H0Y720_HUMAN" 2 1446.5973 4.43 48755 14805 2 1446.599673 724.3059 Trinucleotide repeat-containing gene 6B protein OS=Homo sapiens OX=9606 GN=TNRC6B PE=1 SV=4 4.03 2704.7 - 475640 - - - 1.6328 - 1.903 0.642 - 235.4 1 2 0 0.0024 13 0 0 0 3.79E+06 8.55E+05 - - - 5.4335 0.997 221125_WJC_METTL3_EV_vs_WT_F04.14806.14806.3 0.0635 Sep-36 R.LK[136.11]LPANWEAK[136.11].K sp|O95926|SYF2_HUMAN 1 1184.6888 1.57 48756 14806 3 1184.690317 395.9036 Pre-mRNA-splicing factor SYF2 OS=Homo sapiens OX=9606 GN=SYF2 PE=1 SV=1 8.59 2704.8 - 349612 - - - 1.2434 - 1.68 0.334 - 81.4 1 2 1 0.0015 10 0 0 0 4.09E+06 2.61E+06 - - - 3.7785 0.9987 221125_WJC_METTL3_EV_vs_WT_F04.14808.14808.3 0.0761 13/56 R.FVQEVVQSQQVAVGR[166.11].Q "sp|Q92888|ARHG1_HUMAN,tr|M0QZR4|M0QZR4_HUMAN,tr|M0R3H5|M0R3H5_HUMAN" 3 1682.8979 1.11 48758 14808 3 1682.898651 561.9733 Rho guanine nucleotide exchange factor 1 OS=Homo sapiens OX=9606 GN=ARHGEF1 PE=1 SV=2 6 2705.1 - 325098 - - - 0.4231 - 2.189 0.23 - 252.6 1 2 0 0.0007 15 0 0 0 1.43E+06 1.29E+06 - - - 3.1484 0.9997 221125_WJC_METTL3_EV_vs_WT_F04.14812.14812.2 2.69 13/24 R.GGIGAGLGGGLC[160.03]R.R "sp|Q9NXV2|KCTD5_HUMAN,tr|H3BSS5|H3BSS5_HUMAN" 2 1143.5819 3.67 48760 14812 2 1143.582439 572.7982 BTB\POZ domain-containing protein KCTD5 OS=Homo sapiens OX=9606 GN=KCTD5 PE=1 SV=1 8.25 2705.6 - 1.86E+06 - - - 0.4923 - 2.555 0.309 - 391 1 2 0 0.0006 13 0 0 0 1.43E+07 3.88E+06 - - - 3.7306 1 221125_WJC_METTL3_EV_vs_WT_F04.14813.14813.3 4.88E-07 13/64 R.ISIGGGSC[160.03]AISGGYGSR.A "sp|P48668|K2C6C_HUMAN,sp|P04259|K2C6B_HUMAN,sp|P02538|K2C6A_HUMAN" 3 1597.7519 1918.79 48761 14813 3 1597.752875 533.5912 "Keratin, type II cytoskeletal 6C OS=Homo sapiens OX=9606 GN=KRT6C PE=1 SV=3" 8.22 2705.6 - 2.39E+06 - - - 0.6384 - 2.445 0.516 - 167.3 1 2 0 0.001 17 0 0 0 3.44E+08 1.79E+05 - - - 6.5512 0.9345 221125_WJC_METTL3_EV_vs_WT_F04.14814.14814.2 0.0392 12-Jun Y.AFVHMEK.E sp|Q96PK6|RBM14_HUMAN 1 860.4215 1.34 48762 14814 2 860.42197 431.218 RNA-binding protein 14 OS=Homo sapiens OX=9606 GN=RBM14 PE=1 SV=2 6.79 2705.7 - 1.63E+06 - - - 0.5939 - 1.189 0.372 - 160.6 1 1 0 0.0005 7 0 0 0 1.16E+07 8.70E+06 - - - 2.3369 0.9709 221125_WJC_METTL3_EV_vs_WT_F04.14815.14815.2 0.000974 18-Nov L.NLQIDPTIQR.V sp|P02538|K2C6A_HUMAN 1 1196.6513 999 48763 14815 2 1196.652158 599.3329 "Keratin, type II cytoskeletal 6A OS=Homo sapiens OX=9606 GN=KRT6A PE=1 SV=3" 5.84 2705.8 - 1.42E+06 - - - 0.6869 - 2.098 0.28 - 422.2 1 1 0 0.0008 10 0 0 0 7.52E+07 0.00E+00 - - - 3.1771 1 221125_WJC_METTL3_EV_vs_WT_F04.14820.14820.3 0.00182 17/48 K.VAPPAVLNDISKK.L "sp|Q9Y520|PRC2C_HUMAN,tr|E7EPN9|E7EPN9_HUMAN,tr|H7C5N8|H7C5N8_HUMAN,tr|A0A2R8Y7F4|A0A2R8Y7F4_HUMAN,tr|A0A2R8YET2|A0A2R8YET2_HUMAN" 5 1350.7871 1.96 48768 14820 3 1350.788832 451.2696 Protein PRRC2C OS=Homo sapiens OX=9606 GN=PRRC2C PE=1 SV=4 8.56 2706.4 - 305972 - - - 1.2815 - 3.111 0.42 - 417.5 1 2 0 0.0017 13 0 0 0 2.93E+06 1.49E+06 - - - 6.2993 0.9999 221125_WJC_METTL3_EV_vs_WT_F04.14823.14823.2 2.87E-06 Aug-32 K.IEEVSDTSSLQPQASLK.Q sp|Q9H6T3|RPAP3_HUMAN 1 1830.9211 1.21 48771 14823 2 1830.920845 916.4678 RNA polymerase II-associated protein 3 OS=Homo sapiens OX=9606 GN=RPAP3 PE=1 SV=2 4.14 2706.8 - 184646 - - - -0.1327 - 2.094 0.59 - 141.2 1 2 0 -0.0002 17 0 0 0 1.03E+06 8.54E+05 - - - 5.2157 1 221125_WJC_METTL3_EV_vs_WT_F04.14827.14827.3 2.11E-05 16/64 K.LSHEGPGSELPAGALYR[166.11].K "sp|Q14203|DCTN1_HUMAN,tr|A0A804CDA6|A0A804CDA6_HUMAN,tr|E7EX90|E7EX90_HUMAN,tr|A0A7P0Z4C3|A0A7P0Z4C3_HUMAN,tr|E7EWF7|E7EWF7_HUMAN" 5 1762.8878 2.12 48773 14827 3 1762.888329 588.6365 Dynactin subunit 1 OS=Homo sapiens OX=9606 GN=DCTN1 PE=1 SV=3 5.4 2707.3 - 3.94E+06 - - - 0.3182 - 2.425 0.492 - 298.7 1 2 0 0.0006 17 0 0 0 7.19E+08 3.40E+08 - - - 6.263 1 221125_WJC_METTL3_EV_vs_WT_F04.14829.14829.2 4.20E-06 15/24 R.FSGSGSGTDFTLK.L "sp|A2NJV5|KV229_HUMAN,sp|A0A087WW87|KV240_HUMAN,sp|P06310|KV230_HUMAN,sp|A0A075B6S2|KVD29_HUMAN,sp|P01614|KVD40_HUMAN,sp|P01615|KVD28_HUMAN,sp|A0A075B6S6|KVD30_HUMAN,sp|A0A075B6P5|KV228_HUMAN,sp|A0A0A0MRZ7|KVD26_HUMAN" 9 1302.6092 118.6 48775 14829 2 1302.610064 652.3119 Immunoglobulin kappa variable 2-29 OS=Homo sapiens OX=9606 GN=IGKV2-29 PE=3 SV=2 5.84 2707.5 - 2.57E+06 - - - 0.6664 - 2.805 0.637 - 486.6 1 2 0 0.0009 13 0 0 0 9.30E+06 7.85E+04 - - - 6.3927 0.763 221125_WJC_METTL3_EV_vs_WT_F04.14831.14831.2 2.76 14-Jun V.AAADLILK.L tr|E5RJZ4|E5RJZ4_HUMAN 1 813.496 999 48777 14831 2 813.49589 407.7553 Lipoprotein lipase OS=Homo sapiens OX=9606 GN=LPL PE=4 SV=1 5.88 2707.6 - 1.26E+06 - - - -0.1401 - 1.447 0.143 - 127.9 2 1 0 -0.0001 8 0 0 0 8.58E+06 0.00E+00 - - - 1.0771 1 221125_WJC_METTL3_EV_vs_WT_F04.14833.14833.2 1.80E-08 22-Dec R.DQFTTTEVNMAR[166.11].V sp|P61758|PFD3_HUMAN 1 1421.6484 0.15 48779 14833 2 1421.64976 711.8315 Prefoldin subunit 3 OS=Homo sapiens OX=9606 GN=VBP1 PE=1 SV=4 4.37 2707.9 - 664279 - - - 0.9222 - 2.465 0.633 - 506.8 1 2 0 0.0013 12 0 0 0 6.53E+05 4.45E+06 - - - 6.0897 0.9984 221125_WJC_METTL3_EV_vs_WT_F04.14835.14835.3 0.0796 Aug-40 R.YFFTSVSRPGR.G "sp|P04439|HLAA_HUMAN,tr|A0A0G2JI36|A0A0G2JI36_HUMAN,tr|Q9GJ45|Q9GJ45_HUMAN,tr|Q53Z42|Q53Z42_HUMAN,tr|Q5RJ27|Q5RJ27_HUMAN,tr|Q5SRN5|Q5SRN5_HUMAN,tr|A0A1W2PS24|A0A1W2PS24_HUMAN,tr|A0A0G2JIF2|A0A0G2JIF2_HUMAN,tr|A0A140T955|A0A140T955_HUMAN,tr|A0A140T913|A0A140T913_HUMAN,tr|Q5SUL5|Q5SUL5_HUMAN,tr|A0A140T975|A0A140T975_HUMAN,tr|A0A140T933|A0A140T933_HUMAN,tr|A0A1W2PSE7|A0A1W2PSE7_HUMAN,tr|A0A1W2PRT9|A0A1W2PRT9_HUMAN,tr|Q5SRN7|Q5SRN7_HUMAN,tr|A0A140T9I0|A0A140T9I0_HUMAN,tr|A0A140T9X5|A0A140T9X5_HUMAN,tr|A0A1W2PS39|A0A1W2PS39_HUMAN,tr|A0A0G2JL56|A0A0G2JL56_HUMAN" 20 1315.6673 0.13 48781 14835 3 1315.668543 439.563 "HLA class I histocompatibility antigen, A alpha chain OS=Homo sapiens OX=9606 GN=HLA-A PE=1 SV=2" 10.84 2708.1 - 527234 - - - 0.9296 - 1.341 0.327 - 60.7 1 2 0 0.0012 11 0 0 0 5.49E+06 4.28E+07 - - - 3.0189 0.8401 221125_WJC_METTL3_EV_vs_WT_F04.14836.14836.2 0.859 22-Jul K.TEELEEESFPER[166.11].S "sp|Q9Y2W1|TR150_HUMAN,tr|A0A3B3ITZ9|A0A3B3ITZ9_HUMAN" 2 1503.6605 0.55 48782 14836 2 1503.664484 752.8375 Thyroid hormone receptor-associated protein 3 OS=Homo sapiens OX=9606 GN=THRAP3 PE=1 SV=2 3.9 2708.2 - 441639 - - - 2.6808 - 1.046 0.056 - 91.8 1 2 0 0.004 12 0 0 0 2.11E+06 3.86E+06 - - - -0.4283 0.9999 221125_WJC_METTL3_EV_vs_WT_F04.14837.14837.3 1.43E-05 13/68 K.IMPIQHTLSVQSASSTVK.K "sp|Q8IWC1|MA7D3_HUMAN,tr|A0A0A0MRP0|A0A0A0MRP0_HUMAN" 2 1926.0244 0.89 48783 14837 3 1926.024068 643.0154 MAP7 domain-containing protein 3 OS=Homo sapiens OX=9606 GN=MAP7D3 PE=1 SV=2 8.76 2708.4 - 390777 - - - -0.1973 - 2.321 0.415 - 99.9 1 2 0 -0.0004 18 0 0 0 6.70E+06 7.53E+06 - - - 5.2634 1 221125_WJC_METTL3_EV_vs_WT_F04.14838.14838.2 4.48E-07 13/34 K.IDSVAAQPTATSPVVYTR.P sp|P49790|NU153_HUMAN 1 1874.9738 3.28 48784 14838 2 1874.976256 938.4942 Nuclear pore complex protein Nup153 OS=Homo sapiens OX=9606 GN=NUP153 PE=1 SV=2 5.84 2708.5 - 229183 - - - 1.3142 - 2.902 0.587 - 237.2 1 1 0 0.0025 18 0 0 0 1.47E+06 4.49E+05 - - - 5.9951 0.8021 221125_WJC_METTL3_EV_vs_WT_F04.14840.14840.2 8.04 22-May R.R[166.11]TTYLVLDEADR[166.11].M "sp|P17844|DDX5_HUMAN,tr|A0A7I2V5F5|A0A7I2V5F5_HUMAN,tr|J3KRZ1|J3KRZ1_HUMAN,tr|J3QSF1|J3QSF1_HUMAN,tr|A0A7I2V507|A0A7I2V507_HUMAN,tr|J3KTA4|J3KTA4_HUMAN,tr|A0A0G2JLI4|A0A0G2JLI4_HUMAN,tr|A0A7I2V2S0|A0A7I2V2S0_HUMAN" 8 1470.7581 1.38 48786 14840 2 1470.761679 736.3863 Probable ATP-dependent RNA helicase DDX5 OS=Homo sapiens OX=9606 GN=DDX5 PE=1 SV=1 4.56 2708.7 - 194201 - - - 2.4015 - 1.232 0.011 - 41.4 7 2 0 0.0035 12 0 0 0 1.87E+06 1.36E+06 - - - -0.7074 1 221125_WJC_METTL3_EV_vs_WT_F04.14843.14843.2 8.77E-10 16/32 R.ISIGGGSC[160.03]AISGGYGSR.A "sp|P48668|K2C6C_HUMAN,sp|P04259|K2C6B_HUMAN,sp|P02538|K2C6A_HUMAN" 3 1597.7519 62806.78 48788 14843 2 1597.752255 799.8832 "Keratin, type II cytoskeletal 6C OS=Homo sapiens OX=9606 GN=KRT6C PE=1 SV=3" 8.22 2709.1 - 1.37E+08 - - - 0.2504 - 3.496 0.657 - 721.3 1 2 0 0.0004 17 0 0 0 5.55E+09 8.84E+04 - - - 6.9706 1 221125_WJC_METTL3_EV_vs_WT_F04.14844.14844.2 2.34E-10 13/28 R.MGNTPDSASDNLGFR.C "sp|Q8NBJ7|SUMF2_HUMAN,tr|A8MXB9|A8MXB9_HUMAN,tr|E9PBT8|E9PBT8_HUMAN,tr|J3KQJ1|J3KQJ1_HUMAN,tr|J3QT17|J3QT17_HUMAN,tr|A0A494C1B1|A0A494C1B1_HUMAN" 6 1580.6889 2.21 48789 14844 2 1580.688855 791.3517 Inactive C-alpha-formylglycine-generating enzyme 2 OS=Homo sapiens OX=9606 GN=SUMF2 PE=1 SV=2 4.21 2709.2 - 540280 - - - -0.0411 - 2.707 0.724 - 437.4 1 2 0 -0.0001 15 0 0 0 3.62E+06 1.63E+06 - - - 6.8368 1 221125_WJC_METTL3_EV_vs_WT_F04.14845.14845.3 1.44E-06 19/48 K.QADLYISEGLHPR[166.11].L "sp|Q92526|TCPW_HUMAN,sp|P40227|TCPZ_HUMAN" 2 1507.7659 0.45 48790 14845 3 1507.764439 503.5959 T-complex protein 1 subunit zeta-2 OS=Homo sapiens OX=9606 GN=CCT6B PE=1 SV=5 5.32 2709.3 - 4.02E+06 - - - -0.9438 - 2.994 0.529 - 573.1 1 2 0 -0.0014 13 0 0 0 1.27E+09 2.80E+09 - - - 7.4107 1 221125_WJC_METTL3_EV_vs_WT_F04.14847.14847.2 2.52E-07 24-Dec K.YDYNSGEELESYK[136.11].G "sp|Q9Y3F4|STRAP_HUMAN,tr|H0YH33|H0YH33_HUMAN" 2 1603.6769 0.26 48792 14847 2 1603.675181 802.8458 Serine-threonine kinase receptor-associated protein OS=Homo sapiens OX=9606 GN=STRAP PE=1 SV=1 4 2709.4 - 7.35E+06 - - - -1.1018 - 2.299 0.671 - 327.5 1 2 0 -0.0018 13 0 0 0 1.17E+07 4.49E+07 - - - 6.133 1 221125_WJC_METTL3_EV_vs_WT_F04.14849.14849.2 5.44E-09 16/30 R.LSSLNQDNSLAEDNLK.L sp|Q15643|TRIPB_HUMAN 1 1759.8588 2.29 48794 14849 2 1759.856994 880.9367 Thyroid receptor-interacting protein 11 OS=Homo sapiens OX=9606 GN=TRIP11 PE=1 SV=3 4.03 2709.5 - 1.91E+06 - - - -1.0387 - 3.296 0.669 - 857.1 1 2 0 -0.0018 16 0 0 0 5.72E+08 2.50E+08 - - - 6.914 0.998 221125_WJC_METTL3_EV_vs_WT_F04.14851.14851.2 0.000736 14-Dec R.HYLFDVQR[166.11].N "sp|P24539|AT5F1_HUMAN,tr|Q5QNZ2|Q5QNZ2_HUMAN" 2 1086.5486 2.18 48796 14851 2 1086.544218 544.2816 "ATP synthase F(0) complex subunit B1, mitochondrial OS=Homo sapiens OX=9606 GN=ATP5PB PE=1 SV=2" 6.74 2709.7 - 1.17E+06 - - - -4.032 - 1.735 0.448 - 505.1 1 2 0 -0.0044 8 0 0 0 6.84E+07 3.14E+07 - - - 4.0104 0.9997 221125_WJC_METTL3_EV_vs_WT_F04.14854.14854.3 0.000241 Nov-48 K.YGGPYHIGGSPFK[136.11].A "sp|P21333|FLNA_HUMAN,tr|A0A7P0NMY4|A0A7P0NMY4_HUMAN,tr|Q60FE5|Q60FE5_HUMAN" 3 1386.6812 0.35 48799 14854 3 1386.682571 463.2343 Filamin-A OS=Homo sapiens OX=9606 GN=FLNA PE=1 SV=4 8.5 2710.1 - 679186 - - - 0.9988 - 1.902 0.37 - 80.5 1 2 0 0.0014 13 0 0 0 7.89E+06 2.26E+07 - - - 4.4079 0.9999 221125_WJC_METTL3_EV_vs_WT_F04.14855.14855.3 0.00686 Dec-52 K.LSVVEYDPGTHDLK[136.11].T "sp|Q10570|CPSF1_HUMAN,tr|E9PIM1|E9PIM1_HUMAN" 2 1579.7973 1.03 48800 14855 3 1579.797827 527.6064 Cleavage and polyadenylation specificity factor subunit 1 OS=Homo sapiens OX=9606 GN=CPSF1 PE=1 SV=2 4.54 2710.1 - 660407 - - - 0.3095 - 2.461 0.356 - 170 1 2 0 0.0005 14 0 0 0 9.75E+06 9.44E+06 - - - 4.9022 0.9999 221125_WJC_METTL3_EV_vs_WT_F04.14856.14856.2 3.25E-05 20-Dec K.DVLSSSLEEQK.Q "sp|Q15643|TRIPB_HUMAN,tr|H0YJ97|H0YJ97_HUMAN" 2 1233.6089 2.61 48801 14856 2 1233.608778 617.8117 Thyroid receptor-interacting protein 11 OS=Homo sapiens OX=9606 GN=TRIP11 PE=1 SV=3 4.14 2710.3 - 606350 - - - -0.0681 - 2.475 0.488 - 403 1 2 0 -0.0001 11 0 0 0 4.62E+08 1.77E+08 - - - 5.0969 0.9999 221125_WJC_METTL3_EV_vs_WT_F04.14858.14858.3 0.000957 14/68 K.IMPIQHTLSVQSASSTVK[136.11].K "sp|Q8IWC1|MA7D3_HUMAN,tr|A0A0A0MRP0|A0A0A0MRP0_HUMAN" 2 1934.0386 0.89 48803 14858 3 1934.040253 645.6868 MAP7 domain-containing protein 3 OS=Homo sapiens OX=9606 GN=MAP7D3 PE=1 SV=2 8.76 2710.5 - 508968 - - - 0.8299 - 2.515 0.416 - 153.6 1 2 0 0.0016 18 0 0 0 6.70E+06 7.53E+06 - - - 5.4741 0.9661 221125_WJC_METTL3_EV_vs_WT_F04.14860.14860.2 0.000717 16-Sep N.PTWHC[160.03]IVGR.N "sp|Q96FJ2|DYL2_HUMAN,sp|P63167|DYL1_HUMAN" 2 1124.5549 1.75 48805 14860 2 1124.556047 563.2847 "Dynein light chain 2, cytoplasmic OS=Homo sapiens OX=9606 GN=DYNLL2 PE=1 SV=1" 8.68 2710.8 - 376460 - - - 0.9906 - 1.674 0.354 - 330.2 1 1 0 0.0011 9 0 0 0 3.55E+06 2.02E+06 - - - 3.1458 0.968 221125_WJC_METTL3_EV_vs_WT_F04.14861.14861.2 0.264 20-Jun K.QSGESIDIITR.A "sp|Q16531|DDB1_HUMAN,tr|F5GWI0|F5GWI0_HUMAN,tr|F5H2L3|F5H2L3_HUMAN,tr|A0A7P0TAK7|A0A7P0TAK7_HUMAN,tr|A0A7P0T870|A0A7P0T870_HUMAN,tr|A0A7P0Z3Z5|A0A7P0Z3Z5_HUMAN,tr|F5GZY8|F5GZY8_HUMAN,tr|F5GY55|F5GY55_HUMAN,tr|A0A7P0Z4B9|A0A7P0Z4B9_HUMAN,tr|A0A7P0Z4L2|A0A7P0Z4L2_HUMAN,tr|A0A7P0T965|A0A7P0T965_HUMAN" 11 1217.6252 0.39 48806 14861 2 1217.627117 609.8199 DNA damage-binding protein 1 OS=Homo sapiens OX=9606 GN=DDB1 PE=1 SV=1 4.37 2710.9 - 306227 - - - 1.59 - 1.108 0.152 - 51 3 2 0 0.0019 11 0 0 0 4.19E+06 1.07E+07 - - - 0.2274 0.9994 221125_WJC_METTL3_EV_vs_WT_F04.14869.14869.3 3.82E-07 16/52 K.TVPEELVK[136.11]PEELSK[136.11].Y "sp|Q9UMS4|PRP19_HUMAN,tr|H0YGF3|H0YGF3_HUMAN,tr|F5GY56|F5GY56_HUMAN" 3 1612.8895 1.41 48812 14869 3 1612.882025 538.6371 Pre-mRNA-processing factor 19 OS=Homo sapiens OX=9606 GN=PRPF19 PE=1 SV=1 4.49 2711.6 - 2.48E+06 - - - -4.606 - 2.422 0.449 - 225.4 1 2 0 -0.0074 14 0 0 0 1.20E+09 8.52E+08 - - - 5.8947 0.9997 221125_WJC_METTL3_EV_vs_WT_F04.14878.14878.2 0.00016 30-Nov R.LSSLNQDNSLAEDNLK[136.11].L sp|Q15643|TRIPB_HUMAN 1 1767.873 2.29 48818 14878 2 1767.868352 884.9438 Thyroid receptor-interacting protein 11 OS=Homo sapiens OX=9606 GN=TRIP11 PE=1 SV=3 4.03 2712.6 - 1.03E+07 - - - -2.6416 - 2.94 0.523 - 308.8 1 2 0 -0.0047 16 0 0 0 5.72E+08 2.50E+08 - - - 5.5537 0.9928 221125_WJC_METTL3_EV_vs_WT_F04.14879.14879.3 0.0672 Sep-48 R.FSGSGSGTDFTLK.L "sp|A2NJV5|KV229_HUMAN,sp|A0A087WW87|KV240_HUMAN,sp|P06310|KV230_HUMAN,sp|A0A075B6S2|KVD29_HUMAN,sp|P01614|KVD40_HUMAN,sp|P01615|KVD28_HUMAN,sp|A0A075B6S6|KVD30_HUMAN,sp|A0A075B6P5|KV228_HUMAN,sp|A0A0A0MRZ7|KVD26_HUMAN" 9 1302.6092 1778.79 48819 14879 3 1302.605158 435.2103 Immunoglobulin kappa variable 2-29 OS=Homo sapiens OX=9606 GN=IGKV2-29 PE=3 SV=2 5.84 2712.7 - 4.97E+06 - - - -3.0999 - 1.601 0.277 - 59.4 1 2 0 -0.004 13 0 0 0 9.40E+08 5.29E+05 - - - 2.9032 0.9999 221125_WJC_METTL3_EV_vs_WT_F04.14887.14887.2 3.84E-06 20-Nov R.NPEAALSPTFR[166.11].S "sp|Q86U44|MTA70_HUMAN,tr|B4E349|B4E349_HUMAN,tr|F5H6D8|F5H6D8_HUMAN,tr|B4DTN4|B4DTN4_HUMAN" 4 1211.6174 0.02 48823 14887 2 1211.615956 606.816 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 6 2713.7 - 2.10E+06 - - - -1.1976 - 2.466 0.533 - 606.2 1 2 0 -0.0015 11 0 0 0 1.67E+08 1.05E+10 - - - 5.419 1 221125_WJC_METTL3_EV_vs_WT_F04.14891.14891.2 9.19E-10 14/22 F.SGSGSGTDFTLK.L "sp|A2NJV5|KV229_HUMAN,sp|A0A087WW87|KV240_HUMAN,sp|P06310|KV230_HUMAN,sp|A0A075B6S2|KVD29_HUMAN,sp|P01614|KVD40_HUMAN,sp|P01615|KVD28_HUMAN,sp|A0A075B6S6|KVD30_HUMAN,sp|A0A075B6P5|KV228_HUMAN,sp|A0A0A0MRZ7|KVD26_HUMAN" 9 1155.5408 999 48824 14891 2 1155.536341 578.7777 Immunoglobulin kappa variable 2-29 OS=Homo sapiens OX=9606 GN=IGKV2-29 PE=3 SV=2 5.55 2714.2 - 6.42E+06 - - - -3.8432 - 3.032 0.567 - 682.8 1 1 0 -0.0044 12 0 0 0 3.99E+08 0.00E+00 - - - 6.146 0.9997 221125_WJC_METTL3_EV_vs_WT_F04.14894.14894.2 6.09E-07 22-Dec R.GATQQILDEAER[166.11].S "sp|P78371|TCPB_HUMAN,tr|F8VQ14|F8VQ14_HUMAN,tr|F5GWF6|F5GWF6_HUMAN" 3 1339.6607 0.3 48825 14894 2 1339.657091 670.8376 T-complex protein 1 subunit beta OS=Homo sapiens OX=9606 GN=CCT2 PE=1 SV=4 4.14 2714.6 - 2.92E+07 - - - -2.7149 - 2.597 0.552 - 589.1 1 2 0 -0.0036 12 0 0 0 6.57E+08 2.21E+09 - - - 5.628 0.9973 221125_WJC_METTL3_EV_vs_WT_F04.14904.14904.3 0.000862 17/52 K.TVPEELVKPEELSK.Y "sp|Q9UMS4|PRP19_HUMAN,tr|H0YGF3|H0YGF3_HUMAN,tr|F5GY56|F5GY56_HUMAN" 3 1596.8611 1.41 48826 14904 3 1596.852952 533.2943 Pre-mRNA-processing factor 19 OS=Homo sapiens OX=9606 GN=PRPF19 PE=1 SV=1 4.49 2716.2 - 4.61E+06 - - - -5.0737 - 2.554 0.336 - 235.4 1 2 0 -0.0081 14 0 0 0 1.18E+09 8.37E+08 - - - 4.7757 1 221125_WJC_METTL3_EV_vs_WT_F04.14926.14926.2 1.53E-08 14/22 R.GATQQILDEAER.S "sp|P78371|TCPB_HUMAN,tr|F8VQ14|F8VQ14_HUMAN,tr|F5GWF6|F5GWF6_HUMAN" 3 1329.6525 0.3 48830 14926 2 1329.643662 665.8335 T-complex protein 1 subunit beta OS=Homo sapiens OX=9606 GN=CCT2 PE=1 SV=4 4.14 2719.2 - 1.86E+07 - - - -6.6153 - 2.872 0.621 - 965.6 1 2 0 -0.0088 12 0 0 0 6.57E+08 2.17E+09 - - - 6.4009 0.9994 221125_WJC_METTL3_EV_vs_WT_F04.14927.14927.3 1.78E-05 17/52 K.ILIANTGMDTDKIK.L "sp|P78371|TCPB_HUMAN,tr|F8VQ14|F8VQ14_HUMAN,tr|F5GWF6|F5GWF6_HUMAN" 3 1531.828 0.26 48831 14927 3 1531.821513 511.6166 T-complex protein 1 subunit beta OS=Homo sapiens OX=9606 GN=CCT2 PE=1 SV=4 5.96 2719.3 - 5.37E+06 - - - -4.2218 - 3.58 0.502 - 342.2 1 2 1 -0.0065 14 0 0 0 7.72E+07 3.00E+08 - - - 7.5243 0.9998 221125_WJC_METTL3_EV_vs_WT_F04.14934.14934.3 1.33E-09 19/52 K.ILIANTGMDTDK[136.11]IK[136.11].L "sp|P78371|TCPB_HUMAN,tr|F8VQ14|F8VQ14_HUMAN,tr|F5GWF6|F5GWF6_HUMAN" 3 1547.8564 0.26 48832 14934 3 1547.851731 516.9594 T-complex protein 1 subunit beta OS=Homo sapiens OX=9606 GN=CCT2 PE=1 SV=4 5.96 2720.4 - 5.69E+06 - - - -3.0035 - 3.469 0.573 - 432.3 1 2 1 -0.0046 14 0 0 0 7.72E+07 3.01E+08 - - - 8.2327 0.9999 221125_WJC_METTL3_EV_vs_WT_F04.14939.14939.2 6.78E-06 20-Nov R.TNAENEFVTIK.K sp|P04264|K2C1_HUMAN 1 1264.6299 999 48833 14939 2 1264.630753 633.3222 "Keratin, type II cytoskeletal 1 OS=Homo sapiens OX=9606 GN=KRT1 PE=1 SV=6" 4.53 2721.1 - 1.07E+07 - - - 0.6492 - 2.496 0.512 - 464.8 1 2 0 0.0008 11 0 0 0 1.63E+10 0.00E+00 - - - 5.2968 0.9998 221125_WJC_METTL3_EV_vs_WT_F04.14940.14940.3 0.00117 13/40 K.QQHVIETLIGK[136.11].K "sp|P48643|TCPE_HUMAN,tr|E9PCA1|E9PCA1_HUMAN,tr|B7ZAR1|B7ZAR1_HUMAN,tr|E7ENZ3|E7ENZ3_HUMAN" 4 1272.7281 0.61 48834 14940 3 1272.724605 425.25 T-complex protein 1 subunit epsilon OS=Homo sapiens OX=9606 GN=CCT5 PE=1 SV=1 6.75 2721.2 - 4.45E+06 - - - -2.7744 - 2.065 0.463 - 305 1 2 0 -0.0035 11 0 0 0 3.62E+08 5.97E+08 - - - 5.761 1 221125_WJC_METTL3_EV_vs_WT_F04.14941.14941.3 2.25E-08 15/32 R.VVHIMDFQR[166.11].G "sp|P43243|MATR3_HUMAN,tr|D6RE02|D6RE02_HUMAN,tr|B3KM87|B3KM87_HUMAN,tr|A8MXP9|A8MXP9_HUMAN,tr|D6RAY2|D6RAY2_HUMAN,tr|D6R991|D6R991_HUMAN,tr|A0A0R4J2E8|A0A0R4J2E8_HUMAN,tr|D6RAM9|D6RAM9_HUMAN,tr|D6RIA2|D6RIA2_HUMAN,tr|H0Y8T4|H0Y8T4_HUMAN,tr|D6REM6|D6REM6_HUMAN,tr|D6RBI2|D6RBI2_HUMAN" 12 1153.5942 1.23 48835 14941 3 1153.590785 385.5387 Matrin-3 OS=Homo sapiens OX=9606 GN=MATR3 PE=1 SV=2 6.71 2721.3 - 4.46E+06 - - - -2.9334 - 2.565 0.606 - 597.7 1 2 0 -0.0034 9 0 0 0 1.09E+09 8.83E+08 - - - 8.1342 0.9981 221125_WJC_METTL3_EV_vs_WT_F04.14945.14945.2 8.50E-06 13/20 K.QQHVIETLIGK[136.11].K "sp|P48643|TCPE_HUMAN,tr|E9PCA1|E9PCA1_HUMAN,tr|B7ZAR1|B7ZAR1_HUMAN,tr|E7ENZ3|E7ENZ3_HUMAN" 4 1272.7281 0.38 48837 14945 2 1272.721635 637.3713 T-complex protein 1 subunit epsilon OS=Homo sapiens OX=9606 GN=CCT5 PE=1 SV=1 6.75 2721.7 - 1.09E+07 - - - -5.1079 - 2.4 0.547 - 540.7 1 2 0 -0.0065 11 0 0 0 7.98E+07 2.12E+08 - - - 5.4475 0.9997 221125_WJC_METTL3_EV_vs_WT_F04.14948.14948.3 0.00274 Dec-40 K.QQHVIETLIGK.K "sp|P48643|TCPE_HUMAN,tr|E9PCA1|E9PCA1_HUMAN,tr|B7ZAR1|B7ZAR1_HUMAN,tr|E7ENZ3|E7ENZ3_HUMAN" 4 1264.7139 0.61 48838 14948 3 1264.709782 422.5786 T-complex protein 1 subunit epsilon OS=Homo sapiens OX=9606 GN=CCT5 PE=1 SV=1 6.75 2722.1 - 3.06E+06 - - - -3.2845 - 2.09 0.456 - 250.7 1 2 0 -0.0042 11 0 0 0 3.62E+08 5.96E+08 - - - 5.717 0.9512 221125_WJC_METTL3_EV_vs_WT_F04.14955.14955.2 0.0161 22-Aug R.MSVEADINGLRR.V "sp|P02533|K1C14_HUMAN,sp|P08727|K1C19_HUMAN,tr|C9JM50|C9JM50_HUMAN,tr|K7EMS3|K7EMS3_HUMAN" 4 1359.6929 999 48840 14955 2 1359.685712 680.8537 "Keratin, type I cytoskeletal 14 OS=Homo sapiens OX=9606 GN=KRT14 PE=1 SV=4" 5.82 2723 - 1.71E+07 - - - -5.274 - 1.354 0.255 - 71.1 1 2 0 -0.0072 12 0 0 0 8.03E+08 0.00E+00 - - - 1.7196 0.9999 221125_WJC_METTL3_EV_vs_WT_F04.14956.14956.3 3.61E-09 15/32 R.VVHIMDFQR.G "sp|P43243|MATR3_HUMAN,tr|D6RE02|D6RE02_HUMAN,tr|B3KM87|B3KM87_HUMAN,tr|A8MXP9|A8MXP9_HUMAN,tr|D6RAY2|D6RAY2_HUMAN,tr|D6R991|D6R991_HUMAN,tr|A0A0R4J2E8|A0A0R4J2E8_HUMAN,tr|D6RAM9|D6RAM9_HUMAN,tr|D6RIA2|D6RIA2_HUMAN,tr|H0Y8T4|H0Y8T4_HUMAN,tr|D6REM6|D6REM6_HUMAN,tr|D6RBI2|D6RBI2_HUMAN" 12 1143.5859 1.23 48841 14956 3 1143.581016 382.2026 Matrin-3 OS=Homo sapiens OX=9606 GN=MATR3 PE=1 SV=2 6.71 2723.1 - 1.16E+07 - - - -4.2699 - 2.578 0.624 - 586.7 1 2 0 -0.0049 9 0 0 0 1.09E+09 8.83E+08 - - - 8.3497 0.9997 221125_WJC_METTL3_EV_vs_WT_F04.14961.14961.2 1.19E-09 15/28 K.IEDLSQQAQLAAAEK[136.11].F "sp|E9PAV3|NACAM_HUMAN,sp|Q13765|NACA_HUMAN,tr|A0A7I2V473|A0A7I2V473_HUMAN,tr|F8VZJ2|F8VZJ2_HUMAN,tr|F8VNW4|F8VNW4_HUMAN,tr|A0A7I2V2K5|A0A7I2V2K5_HUMAN,tr|F8W0W4|F8W0W4_HUMAN,tr|H0YHX9|H0YHX9_HUMAN" 8 1621.8403 0.35 48843 14961 2 1621.836705 811.9274 "Nascent polypeptide-associated complex subunit alpha, muscle-specific form OS=Homo sapiens OX=9606 GN=NACA PE=1 SV=1" 4.14 2723.6 - 7.82E+06 - - - -2.195 - 3.008 0.434 - 616.9 1 2 0 -0.0036 15 0 0 0 2.08E+08 5.89E+08 - - - 4.9529 0.9998 221125_WJC_METTL3_EV_vs_WT_F04.14963.14963.2 4.26E-05 16-Nov R.VVHIMDFQR[166.11].G "sp|P43243|MATR3_HUMAN,tr|D6RE02|D6RE02_HUMAN,tr|B3KM87|B3KM87_HUMAN,tr|A8MXP9|A8MXP9_HUMAN,tr|D6RAY2|D6RAY2_HUMAN,tr|D6R991|D6R991_HUMAN,tr|A0A0R4J2E8|A0A0R4J2E8_HUMAN,tr|D6RAM9|D6RAM9_HUMAN,tr|D6RIA2|D6RIA2_HUMAN,tr|H0Y8T4|H0Y8T4_HUMAN,tr|D6REM6|D6REM6_HUMAN,tr|D6RBI2|D6RBI2_HUMAN" 12 1153.5942 1.14 48844 14963 2 1153.593085 577.8044 Matrin-3 OS=Homo sapiens OX=9606 GN=MATR3 PE=1 SV=2 6.71 2723.9 - 5.89E+06 - - - -0.9397 - 1.76 0.47 - 512.4 1 2 0 -0.0011 9 0 0 0 3.11E+08 2.72E+08 - - - 4.1476 0.9999 221125_WJC_METTL3_EV_vs_WT_F04.14970.14970.3 3.09E-06 14/44 K.HIMGQNVADYMR[166.11].Y "sp|P46777|RL5_HUMAN,tr|A0A2R8Y6J3|A0A2R8Y6J3_HUMAN" 2 1443.6627 0.55 48845 14970 3 1443.657822 482.2282 60S ribosomal protein L5 OS=Homo sapiens OX=9606 GN=RPL5 PE=1 SV=3 6.74 2724.9 - 6.06E+06 - - - -3.3505 - 2.563 0.574 - 407.7 1 2 0 -0.0048 12 0 0 0 3.71E+07 6.70E+07 - - - 7.547 0.9999 221125_WJC_METTL3_EV_vs_WT_F04.14976.14976.3 2.06E-05 Nov-40 R.NPEAALSPTFR[166.11].S "sp|Q86U44|MTA70_HUMAN,tr|B4E349|B4E349_HUMAN,tr|F5H6D8|F5H6D8_HUMAN,tr|B4DTN4|B4DTN4_HUMAN" 4 1211.6174 0.01 48847 14976 3 1211.616766 404.8797 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 6 2725.7 - 4.32E+06 - - - -0.529 - 2.243 0.4 - 280.6 1 2 0 -0.0006 11 0 0 0 5.11E+06 4.11E+08 - - - 5.2943 0.9998 221125_WJC_METTL3_EV_vs_WT_F04.14977.14977.2 0.000156 18-Sep K.EAFNMIDQNR.D "sp|O14950|ML12B_HUMAN,sp|P19105|ML12A_HUMAN,sp|P24844|MYL9_HUMAN,tr|J3KTJ1|J3KTJ1_HUMAN,tr|J3QRS3|J3QRS3_HUMAN" 5 1236.5557 1.95 48848 14977 2 1236.555676 619.2851 Myosin regulatory light chain 12B OS=Homo sapiens OX=9606 GN=MYL12B PE=1 SV=2 4.37 2725.8 - 3.70E+06 - - - -0.0364 - 1.769 0.51 - 328 1 2 0 0 10 0 0 0 1.16E+08 5.97E+07 - - - 4.4 0.9994 221125_WJC_METTL3_EV_vs_WT_F04.14981.14981.3 0.00024 Oct-44 R.MSVEADINGLRR.V "sp|P02533|K1C14_HUMAN,sp|P08727|K1C19_HUMAN,tr|C9JM50|C9JM50_HUMAN,tr|K7EMS3|K7EMS3_HUMAN" 4 1359.6929 7132.27 48850 14981 3 1359.688977 454.2382 "Keratin, type I cytoskeletal 14 OS=Homo sapiens OX=9606 GN=KRT14 PE=1 SV=4" 5.82 2726.3 - 6.78E+07 - - - -2.8727 - 1.763 0.407 - 142.7 1 2 0 -0.0039 12 0 0 0 2.55E+09 3.57E+05 - - - 4.6483 0.9999 221125_WJC_METTL3_EV_vs_WT_F04.14986.14986.3 0.00116 14/36 R.TLEGELHDLR.G "sp|P02545|LMNA_HUMAN,tr|A0A6Q8PF80|A0A6Q8PF80_HUMAN,tr|A0A804HL68|A0A804HL68_HUMAN,tr|Q5TCI8|Q5TCI8_HUMAN,tr|A0A6Q8PFJ0|A0A6Q8PFJ0_HUMAN,tr|A0A6Q8PHQ9|A0A6Q8PHQ9_HUMAN,tr|A0A6Q8PGH0|A0A6Q8PGH0_HUMAN,tr|Q3BDU5|Q3BDU5_HUMAN" 8 1181.6041 1.91 48851 14986 3 1181.600905 394.8753 Prelamin-A\C OS=Homo sapiens OX=9606 GN=LMNA PE=1 SV=1 4.65 2727 - 2.71E+06 - - - -2.6625 - 2.655 0.443 - 334.1 1 2 0 -0.0031 10 0 0 0 5.51E+07 2.89E+07 - - - 6.3298 0.9999 221125_WJC_METTL3_EV_vs_WT_F04.14988.14988.2 0.000902 16/28 K.IEDLSQQAQLAAAEK.F "sp|E9PAV3|NACAM_HUMAN,sp|Q13765|NACA_HUMAN,tr|A0A7I2V473|A0A7I2V473_HUMAN,tr|F8VZJ2|F8VZJ2_HUMAN,tr|F8VNW4|F8VNW4_HUMAN,tr|A0A7I2V2K5|A0A7I2V2K5_HUMAN,tr|F8W0W4|F8W0W4_HUMAN,tr|H0YHX9|H0YHX9_HUMAN" 8 1613.8261 0.35 48852 14988 2 1613.824947 807.9203 "Nascent polypeptide-associated complex subunit alpha, muscle-specific form OS=Homo sapiens OX=9606 GN=NACA PE=1 SV=1" 4.14 2727.2 - 8.82E+06 - - - -0.6928 - 3.112 0.472 - 792.6 1 2 0 -0.0011 15 0 0 0 2.08E+08 5.89E+08 - - - 5.3179 0.9999 221125_WJC_METTL3_EV_vs_WT_F04.14989.14989.3 5.10E-07 15/44 K.AEHDQLLLNYAK.K "sp|P20700|LMNB1_HUMAN,tr|A0A0D9SFY5|A0A0D9SFY5_HUMAN,tr|E9PBF6|E9PBF6_HUMAN,tr|A0A0D9SFE5|A0A0D9SFE5_HUMAN" 4 1413.7252 1.5 48853 14989 3 1413.721698 472.249 Lamin-B1 OS=Homo sapiens OX=9606 GN=LMNB1 PE=1 SV=2 5.32 2727.4 - 1.54E+06 - - - -2.4977 - 2.746 0.483 - 303.3 1 2 0 -0.0035 12 0 0 0 1.36E+08 9.09E+07 - - - 6.724 1 221125_WJC_METTL3_EV_vs_WT_F04.14990.14990.2 1.68E-07 13/20 R.NPEAALSPTFR.S "sp|Q86U44|MTA70_HUMAN,tr|B4E349|B4E349_HUMAN,tr|F5H6D8|F5H6D8_HUMAN,tr|B4DTN4|B4DTN4_HUMAN" 4 1201.6091 0.02 48854 14990 2 1201.603927 601.8118 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 6 2727.5 - 3.39E+06 - - - -4.3359 - 2.753 0.636 - 945 1 2 0 -0.0052 11 0 0 0 1.67E+08 1.03E+10 - - - 6.4764 0.9998 221125_WJC_METTL3_EV_vs_WT_F04.14993.14993.3 0.00019 13/44 K.AEHDQLLLNYAK[136.11].K "sp|P20700|LMNB1_HUMAN,tr|A0A0D9SFY5|A0A0D9SFY5_HUMAN,tr|E9PBF6|E9PBF6_HUMAN,tr|A0A0D9SFE5|A0A0D9SFE5_HUMAN" 4 1421.7394 1.5 48855 14993 3 1421.735309 474.9204 Lamin-B1 OS=Homo sapiens OX=9606 GN=LMNB1 PE=1 SV=2 5.32 2727.8 - 4.96E+06 - - - -2.8979 - 2.566 0.427 - 360.1 1 2 0 -0.0041 12 0 0 0 1.36E+08 9.09E+07 - - - 5.9115 0.9973 221125_WJC_METTL3_EV_vs_WT_F04.14995.14995.3 5.60E-06 23/48 Y.TTTPALVFGKPVR.V "sp|P43243|MATR3_HUMAN,tr|B3KM87|B3KM87_HUMAN,tr|A8MXP9|A8MXP9_HUMAN,tr|D6RBK5|D6RBK5_HUMAN,tr|A0A0R4J2E8|A0A0R4J2E8_HUMAN,tr|H0Y8T4|H0Y8T4_HUMAN,tr|D6REM6|D6REM6_HUMAN" 7 1385.8031 1.24 48856 14995 3 1385.800196 462.9416 Matrin-3 OS=Homo sapiens OX=9606 GN=MATR3 PE=1 SV=2 11 2728.1 - 2.87E+06 - - - -2.0847 - 3.582 0.509 - 975 1 1 0 -0.0029 13 0 0 0 7.60E+07 6.12E+07 - - - 7.6734 0.9997 221125_WJC_METTL3_EV_vs_WT_F04.14998.14998.3 2.43E-05 18/48 R.EQDLPLAEAVR[166.11]PK[136.11].T sp|Q96A49|SYAP1_HUMAN 1 1482.8161 1.73 48857 14998 3 1482.813249 495.2793 Synapse-associated protein 1 OS=Homo sapiens OX=9606 GN=SYAP1 PE=1 SV=1 4.68 2728.4 - 4.05E+06 - - - -1.9315 - 2.061 0.388 - 400 1 2 0 -0.0029 13 0 0 0 3.46E+08 2.00E+08 - - - 4.8258 1 221125_WJC_METTL3_EV_vs_WT_F04.14999.14999.3 9.05E-08 18/64 K.LSHEGPGSELPAGALYR.K "sp|Q14203|DCTN1_HUMAN,tr|A0A804CDA6|A0A804CDA6_HUMAN,tr|E7EX90|E7EX90_HUMAN,tr|A0A7P0Z4C3|A0A7P0Z4C3_HUMAN,tr|E7EWF7|E7EWF7_HUMAN" 5 1752.8795 2.12 48858 14999 3 1752.884174 585.3004 Dynactin subunit 1 OS=Homo sapiens OX=9606 GN=DCTN1 PE=1 SV=3 5.4 2728.6 - 2.42E+06 - - - 2.6676 - 2.85 0.577 - 351.2 1 2 0 0.0047 17 0 0 0 7.20E+08 3.40E+08 - - - 7.6175 1 221125_WJC_METTL3_EV_vs_WT_F04.15006.15006.2 5.53E-09 15/26 K.VYETDNNIVVYKGE.- "sp|Q03393|PTPS_HUMAN,tr|E9PNN3|E9PNN3_HUMAN" 2 1641.7886 20.18 48861 15006 2 1641.786226 821.9016 6-pyruvoyl tetrahydrobiopterin synthase OS=Homo sapiens OX=9606 GN=PTS PE=1 SV=1 4.43 2729.5 - 2.79E+06 - - - -1.4563 - 2.824 0.69 - 439.8 1 2 1 -0.0024 14 0 0 0 5.02E+07 2.49E+06 - - - 6.7418 0.9998 221125_WJC_METTL3_EV_vs_WT_F04.15010.15010.3 5.20E-05 Dec-40 K.NMSVHLSPC[160.03]FR.D "sp|P62280|RS11_HUMAN,tr|M0R1H5|M0R1H5_HUMAN,tr|M0QZC5|M0QZC5_HUMAN" 3 1346.6224 0.82 48862 15010 3 1346.618616 449.8814 40S ribosomal protein S11 OS=Homo sapiens OX=9606 GN=RPS11 PE=1 SV=3 8.26 2730.1 - 5.10E+06 - - - -2.781 - 2.148 0.435 - 205.2 1 2 0 -0.0037 11 0 0 0 4.30E+08 5.23E+08 - - - 5.5607 1 221125_WJC_METTL3_EV_vs_WT_F04.15016.15016.3 9.66E-05 20/48 R.SEVELAAALSDKR.G sp|Q03252|LMNB2_HUMAN 1 1387.7307 1.32 48866 15016 3 1387.731518 463.5842 Lamin-B2 OS=Homo sapiens OX=9606 GN=LMNB2 PE=1 SV=4 4.68 2730.8 - 3.09E+06 - - - 0.5837 - 3.267 0.401 - 643.4 1 2 0 0.0008 13 0 0 0 7.43E+07 5.64E+07 - - - 6.2204 0.9986 221125_WJC_METTL3_EV_vs_WT_F04.15021.15021.3 0.00308 Nov-40 R.TNAENEFVTIK.K sp|P04264|K2C1_HUMAN 1 1264.6299 5.73 48869 15021 3 1264.628363 422.5506 "Keratin, type II cytoskeletal 1 OS=Homo sapiens OX=9606 GN=KRT1 PE=1 SV=6" 4.53 2731.4 - 3.93E+06 - - - -1.2407 - 2.078 0.229 - 163.3 1 2 0 -0.0016 11 0 0 0 1.50E+08 2.62E+07 - - - 3.1705 1 221125_WJC_METTL3_EV_vs_WT_F04.15026.15026.3 1.98E-07 22/48 R.SEVELAAALSDK[136.11]R[166.11].G sp|Q03252|LMNB2_HUMAN 1 1405.7532 1.32 48872 15026 3 1405.752016 469.5917 Lamin-B2 OS=Homo sapiens OX=9606 GN=LMNB2 PE=1 SV=4 4.68 2732 - 2.75E+06 - - - -0.8266 - 3.635 0.473 - 842 1 2 0 -0.0012 13 0 0 0 7.43E+07 5.64E+07 - - - 7.3124 0.9997 221125_WJC_METTL3_EV_vs_WT_F04.15031.15031.3 0.000118 Dec-40 K.SKTPEIYLAYR.N "sp|Q8TAQ2|SMRC2_HUMAN,sp|Q92922|SMRC1_HUMAN,tr|F8VXC8|F8VXC8_HUMAN" 3 1339.7136 1.86 48875 15031 3 1339.711415 447.5785 SWI\SNF complex subunit SMARCC2 OS=Homo sapiens OX=9606 GN=SMARCC2 PE=1 SV=1 8.22 2732.5 - 8.64E+06 - - - -1.6324 - 2.368 0.452 - 187.1 1 2 1 -0.0022 11 0 0 0 1.31E+08 7.02E+07 - - - 6.0277 0.9996 221125_WJC_METTL3_EV_vs_WT_F04.15032.15032.3 2.76E-05 Dec-36 R.VNIGEVLDK[136.11]R[166.11].Y "sp|Q13523|PRP4B_HUMAN,tr|H0YDJ3|H0YDJ3_HUMAN" 2 1159.668 1.21 48876 15032 3 1159.663758 387.5633 Serine\threonine-protein kinase PRP4 homolog OS=Homo sapiens OX=9606 GN=PRPF4B PE=1 SV=3 6.04 2732.7 - 679836 - - - -3.651 - 2.158 0.428 - 253.4 1 2 0 -0.0042 10 0 0 0 1.49E+07 1.24E+07 - - - 5.557 0.9995 221125_WJC_METTL3_EV_vs_WT_F04.15034.15034.3 0.00708 Oct-40 K.KQPSVLVTFPK.E "sp|O75179|ANR17_HUMAN,tr|H0YM23|H0YM23_HUMAN" 2 1242.7336 3.82 48878 15034 3 1242.730236 415.2518 Ankyrin repeat domain-containing protein 17 OS=Homo sapiens OX=9606 GN=ANKRD17 PE=1 SV=3 10 2732.9 - 1.53E+06 - - - -2.7142 - 2.089 0.374 - 156.7 1 2 0 -0.0034 11 0 0 0 2.59E+07 6.79E+06 - - - 4.8016 0.9915 221125_WJC_METTL3_EV_vs_WT_F04.15040.15040.2 0.0035 14/22 K.EGLELPEDEEEK.K "sp|Q58FG0|HS905_HUMAN,sp|P08238|HS90B_HUMAN,sp|Q58FF6|H90B4_HUMAN,sp|Q58FF7|H90B3_HUMAN,sp|P07900|HS90A_HUMAN" 5 1415.6304 999 48882 15040 2 1415.62157 708.8225 Putative heat shock protein HSP 90-alpha A5 OS=Homo sapiens OX=9606 GN=HSP90AA5P PE=2 SV=1 3.77 2733.6 - 3.40E+06 - - - -6.2269 - 2.655 0.346 - 559.6 1 2 0 -0.0088 12 0 0 0 7.05E+07 0.00E+00 - - - 4.163 0.999 221125_WJC_METTL3_EV_vs_WT_F04.15043.15043.3 0.00134 Oct-40 K.NMSVHLSPC[160.03]FR[166.11].D "sp|P62280|RS11_HUMAN,tr|M0R1H5|M0R1H5_HUMAN,tr|M0QZC5|M0QZC5_HUMAN" 3 1356.6306 0.82 48883 15043 3 1356.626721 453.2175 40S ribosomal protein S11 OS=Homo sapiens OX=9606 GN=RPS11 PE=1 SV=3 8.26 2734 - 3.21E+07 - - - -2.8821 - 2.098 0.326 - 132.1 1 2 0 -0.0039 11 0 0 0 4.30E+08 5.23E+08 - - - 4.2785 0.9996 221125_WJC_METTL3_EV_vs_WT_F04.15046.15046.2 9.03E-06 13/28 K.TNGLPVQNGIDADVK.D "sp|Q14671|PUM1_HUMAN,tr|Q5T1Z8|Q5T1Z8_HUMAN,tr|H0YEH2|H0YEH2_HUMAN,tr|Q5T1Z4|Q5T1Z4_HUMAN" 4 1539.7893 2.49 48886 15046 2 1539.786326 770.9019 Pumilio homolog 1 OS=Homo sapiens OX=9606 GN=PUM1 PE=1 SV=3 4.21 2734.3 - 3.87E+06 - - - -1.9223 - 2.403 0.414 - 323.8 1 2 0 -0.003 15 0 0 0 9.57E+07 3.84E+07 - - - 4.2533 0.9999 221125_WJC_METTL3_EV_vs_WT_F04.15047.15047.3 1.23E-06 16/60 R.DLEAEHVEVEDTTLNR.C "sp|Q9H3K6|BOLA2_HUMAN,tr|A0A087WZT3|A0A087WZT3_HUMAN,tr|H3BVE0|H3BVE0_HUMAN,tr|A0A0B4J295|A0A0B4J295_HUMAN,tr|H3BTW0|H3BTW0_HUMAN,tr|H3BV85|H3BV85_HUMAN" 6 1868.8752 1.22 48887 15047 3 1868.870546 623.9657 BolA-like protein 2 OS=Homo sapiens OX=9606 GN=BOLA2 PE=1 SV=1 4.08 2734.4 - 2.47E+06 - - - -2.4908 - 2.401 0.553 - 217.5 1 2 0 -0.0047 16 0 0 0 5.30E+07 4.35E+07 - - - 6.9515 1 221125_WJC_METTL3_EV_vs_WT_F04.15048.15048.2 1.85E-05 17/26 K.TSAALSTVGSAISR.K "sp|O43399|TPD54_HUMAN,tr|A0A087WYR3|A0A087WYR3_HUMAN" 2 1319.7045 1.79 48888 15048 2 1319.698623 660.8595 Tumor protein D54 OS=Homo sapiens OX=9606 GN=TPD52L2 PE=1 SV=2 9.41 2734.5 - 2.29E+06 - - - -4.4487 - 3.476 0.576 - 1063.6 1 2 0 -0.0059 14 0 0 0 6.68E+07 3.72E+07 - - - 6.42 1 221125_WJC_METTL3_EV_vs_WT_F04.15049.15049.2 6.54E-09 15/22 R.EVTEVLQEATC[160.03]K.L "sp|Q5VT06|CE350_HUMAN,tr|H0YD38|H0YD38_HUMAN,tr|H0Y6Q4|H0Y6Q4_HUMAN" 3 1405.6759 4.81 48889 15049 2 1405.664902 703.8452 Centrosome-associated protein 350 OS=Homo sapiens OX=9606 GN=CEP350 PE=1 SV=1 4.25 2734.7 - 1.75E+06 - - - -7.8211 - 2.927 0.573 - 917.7 1 2 0 -0.011 12 0 0 0 1.57E+07 3.27E+06 - - - 6.0955 0.9969 221125_WJC_METTL3_EV_vs_WT_F04.15050.15050.3 0.0975 13/44 K.IEVEKPFAIAKE.- "sp|P23284|PPIB_HUMAN,tr|A0A7P0Z497|A0A7P0Z497_HUMAN,tr|A0A7P0TB45|A0A7P0TB45_HUMAN" 3 1372.7602 0.39 48890 15050 3 1372.761909 458.594 Peptidyl-prolyl cis-trans isomerase B OS=Homo sapiens OX=9606 GN=PPIB PE=1 SV=2 5.01 2734.8 - 1.39E+06 - - - 1.2318 - 2.149 0.182 - 128 1 2 0 0.0017 12 0 0 0 2.79E+07 7.11E+07 - - - 2.6891 0.9756 221125_WJC_METTL3_EV_vs_WT_F04.15051.15051.2 0.0712 16-Oct M.SVHLSPC[160.03]FR[166.11].D "sp|P62280|RS11_HUMAN,tr|M0R1H5|M0R1H5_HUMAN,tr|M0QZC5|M0QZC5_HUMAN" 3 1111.5472 0.76 48891 15051 2 1111.546536 556.7809 40S ribosomal protein S11 OS=Homo sapiens OX=9606 GN=RPS11 PE=1 SV=3 7.99 2734.9 - 975983 - - - -0.6145 - 1.824 0.337 - 361.9 1 1 0 -0.0007 9 0 0 0 9.21E+06 1.22E+07 - - - 3.2687 1 221125_WJC_METTL3_EV_vs_WT_F04.15053.15053.2 2.64E-08 20-Nov K.NMSVHLSPC[160.03]FR.D "sp|P62280|RS11_HUMAN,tr|M0R1H5|M0R1H5_HUMAN,tr|M0QZC5|M0QZC5_HUMAN" 3 1346.6224 3.16 48892 15053 2 1346.622445 674.3185 40S ribosomal protein S11 OS=Homo sapiens OX=9606 GN=RPS11 PE=1 SV=3 8.26 2735.1 - 3.28E+06 - - - 0.0624 - 2.309 0.61 - 541.3 1 2 0 0.0001 11 0 0 0 2.80E+08 8.88E+07 - - - 5.8102 0.9992 221125_WJC_METTL3_EV_vs_WT_F04.15054.15054.3 1.41E-05 16/48 R.SPTLYGISHDDLK[136.11].G "sp|O75643|U520_HUMAN,tr|A0A494C1A5|A0A494C1A5_HUMAN" 2 1452.734 1.99 48893 15054 3 1452.726347 485.2519 U5 small nuclear ribonucleoprotein 200 kDa helicase OS=Homo sapiens OX=9606 GN=SNRNP200 PE=1 SV=2 5.19 2735.2 - 1.97E+06 - - - -5.2742 - 2.545 0.46 - 403.5 1 2 0 -0.0077 13 0 0 0 4.37E+07 2.20E+07 - - - 6.1991 0.9769 221125_WJC_METTL3_EV_vs_WT_F04.15055.15055.3 0.252 Nov-44 K.IEVEK[136.11]PFAIAK[136.11]E.- "sp|P23284|PPIB_HUMAN,tr|A0A7P0Z497|A0A7P0Z497_HUMAN,tr|A0A7P0TB45|A0A7P0TB45_HUMAN" 3 1388.7886 0.39 48894 15055 3 1388.786075 463.9368 Peptidyl-prolyl cis-trans isomerase B OS=Homo sapiens OX=9606 GN=PPIB PE=1 SV=2 5.01 2735.2 - 5.06E+06 - - - -1.8311 - 1.673 0.145 - 94.6 1 2 0 -0.0025 12 0 0 0 2.79E+07 7.11E+07 - - - 1.5823 0.9999 221125_WJC_METTL3_EV_vs_WT_F04.15056.15056.3 7.75E-06 15/48 R.SPTLYGISHDDLK.G "sp|O75643|U520_HUMAN,tr|A0A494C1A5|A0A494C1A5_HUMAN" 2 1444.7198 1.99 48895 15056 3 1444.717153 482.5805 U5 small nuclear ribonucleoprotein 200 kDa helicase OS=Homo sapiens OX=9606 GN=SNRNP200 PE=1 SV=2 5.19 2735.3 - 2.93E+06 - - - -1.8384 - 2.457 0.481 - 363.3 1 2 0 -0.0027 13 0 0 0 4.37E+07 2.20E+07 - - - 6.3392 0.9999 221125_WJC_METTL3_EV_vs_WT_F04.15058.15058.2 6.29E-09 14/26 K.TSAALSTVGSAISR[166.11].K "sp|O43399|TPD54_HUMAN,tr|A0A087WYR3|A0A087WYR3_HUMAN" 2 1329.7128 1.78 48897 15058 2 1329.713017 665.8637 Tumor protein D54 OS=Homo sapiens OX=9606 GN=TPD52L2 PE=1 SV=2 9.41 2735.5 - 2.22E+06 - - - 0.1903 - 2.984 0.465 - 653.3 1 2 0 0.0003 14 0 0 0 6.63E+07 3.72E+07 - - - 5.2189 1 221125_WJC_METTL3_EV_vs_WT_F04.15059.15059.2 3.73E-11 16/26 R.EAAQAMYIDSYNSR[166.11].G sp|Q9BU61|NDUF3_HUMAN 1 1627.7176 1.35 48898 15059 2 1627.722037 814.8661 NADH dehydrogenase [ubiquinone] 1 alpha subcomplex assembly factor 3 OS=Homo sapiens OX=9606 GN=NDUFAF3 PE=1 SV=1 4.37 2735.6 - 1.66E+06 - - - 2.7314 - 3.199 0.641 - 1006.7 1 2 0 0.0044 14 0 0 0 1.93E+07 1.43E+07 - - - 6.6921 0.9946 221125_WJC_METTL3_EV_vs_WT_F04.15060.15060.2 0.000111 18-Nov R.SFSISSNLQR.H "sp|Q03112|MECOM_HUMAN,sp|Q9HAZ2|PRD16_HUMAN,tr|E7EUL6|E7EUL6_HUMAN,tr|A0A0C3SFZ7|A0A0C3SFZ7_HUMAN,tr|D6RDW0|D6RDW0_HUMAN,tr|D6RFY3|D6RFY3_HUMAN,tr|H0YA13|H0YA13_HUMAN" 7 1137.5778 0.93 48899 15060 2 1137.571891 569.7962 Histone-lysine N-methyltransferase MECOM OS=Homo sapiens OX=9606 GN=MECOM PE=1 SV=3 9.47 2735.7 - 1.36E+06 - - - -5.226 - 2.056 0.377 - 431.4 1 2 0 -0.0059 10 0 0 0 1.53E+07 1.63E+07 - - - 3.8355 0.985 221125_WJC_METTL3_EV_vs_WT_F04.15062.15062.2 0.282 16-Nov M.SVHLSPC[160.03]FR.D "sp|P62280|RS11_HUMAN,tr|M0R1H5|M0R1H5_HUMAN,tr|M0QZC5|M0QZC5_HUMAN" 3 1101.5389 0.76 48901 15062 2 1101.538633 551.7768 40S ribosomal protein S11 OS=Homo sapiens OX=9606 GN=RPS11 PE=1 SV=3 7.99 2736 - 1.00E+06 - - - -0.2869 - 1.901 0.389 - 441.1 1 1 0 -0.0003 9 0 0 0 9.21E+06 1.22E+07 - - - 3.7725 0.8085 221125_WJC_METTL3_EV_vs_WT_F04.15063.15063.2 0.0411 20-Jul E.GEEEEVAAVAE.- "sp|Q12766|HMGX3_HUMAN,tr|E9PEK0|E9PEK0_HUMAN" 2 1131.4932 - 48902 15063 2 1131.496477 566.7539 HMG domain-containing protein 3 OS=Homo sapiens OX=9606 GN=HMGXB3 PE=2 SV=3 3.79 2736.1 - 977505 - - - 2.9289 - 1.46 0.325 - 129.1 1 1 0 0.0033 11 0 0 0 - - - - - 2.4642 1 221125_WJC_METTL3_EV_vs_WT_F04.15064.15064.2 2.80E-10 18/34 K.AVTAFSSTETGSAEQGFK.S "sp|Q5JSZ5|PRC2B_HUMAN,tr|A0A804HJR4|A0A804HJR4_HUMAN" 2 1816.8479 5.66 48903 15064 2 1816.848545 909.4312 Protein PRRC2B OS=Homo sapiens OX=9606 GN=PRRC2B PE=1 SV=2 4.53 2736.3 - 828586 - - - 0.3424 - 3.905 0.627 - 1168.5 1 2 0 0.0006 18 0 0 0 9.13E+06 1.61E+06 - - - 7.021 0.9815 221125_WJC_METTL3_EV_vs_WT_F04.15065.15065.2 0.387 24-Jul R.QTGGLGISIAGGK[136.11].G "sp|Q14160|SCRIB_HUMAN,tr|A0A669KB89|A0A669KB89_HUMAN,tr|A0A0G2JPP5|A0A0G2JPP5_HUMAN,tr|H0YDF9|H0YDF9_HUMAN,tr|A0A0G2JNZ2|A0A0G2JNZ2_HUMAN,tr|A0A0G2JMS7|A0A0G2JMS7_HUMAN" 6 1165.6546 0.4 48904 15065 2 1165.651004 583.8346 Protein scribble homolog OS=Homo sapiens OX=9606 GN=SCRIB PE=1 SV=4 8.75 2736.4 - 568472 - - - -3.1167 - 1.251 0.227 - 67.9 1 2 0 -0.0036 13 0 0 0 2.28E+06 5.70E+06 - - - 1.2912 1 221125_WJC_METTL3_EV_vs_WT_F04.15070.15070.3 6.57E-06 15/56 R.TGFSTSPESPYTHWK.Q "sp|Q99873|ANM1_HUMAN,tr|E9PKG1|E9PKG1_HUMAN" 2 1723.7842 1.6 48907 15070 3 1723.782962 575.602 Protein arginine N-methyltransferase 1 OS=Homo sapiens OX=9606 GN=PRMT1 PE=1 SV=3 6.41 2737 - 2.38E+06 - - - -0.7188 - 2.536 0.534 - 182.4 1 2 0 -0.0012 15 0 0 0 2.34E+07 1.46E+07 - - - 6.9215 0.9998 221125_WJC_METTL3_EV_vs_WT_F04.15071.15071.2 0.000564 20-Nov K.NMSVHLSPC[160.03]FR[166.11].D "sp|P62280|RS11_HUMAN,tr|M0R1H5|M0R1H5_HUMAN,tr|M0QZC5|M0QZC5_HUMAN" 3 1356.6306 3.29 48908 15071 2 1356.628058 679.3226 40S ribosomal protein S11 OS=Homo sapiens OX=9606 GN=RPS11 PE=1 SV=3 8.26 2737 - 2.31E+06 - - - -1.8966 - 2.131 0.514 - 514.3 1 2 0 -0.0026 11 0 0 0 2.94E+08 8.91E+07 - - - 4.8834 0.9993 221125_WJC_METTL3_EV_vs_WT_F04.15072.15072.2 2.46E-07 13/28 K.TNGLPVQNGIDADVK[136.11].D "sp|Q14671|PUM1_HUMAN,tr|Q5T1Z8|Q5T1Z8_HUMAN,tr|H0YEH2|H0YEH2_HUMAN,tr|Q5T1Z4|Q5T1Z4_HUMAN" 4 1547.8035 2.47 48909 15072 2 1547.797849 774.909 Pumilio homolog 1 OS=Homo sapiens OX=9606 GN=PUM1 PE=1 SV=3 4.21 2737.1 - 2.23E+06 - - - -3.6419 - 2.695 0.529 - 392.8 1 2 0 -0.0056 15 0 0 0 9.75E+07 3.95E+07 - - - 5.3838 1 221125_WJC_METTL3_EV_vs_WT_F04.15073.15073.2 1.23E-08 15/26 R.EAAQAMYIDSYNSR.G sp|Q9BU61|NDUF3_HUMAN 1 1617.7093 1.35 48910 15073 2 1617.710455 809.8619 NADH dehydrogenase [ubiquinone] 1 alpha subcomplex assembly factor 3 OS=Homo sapiens OX=9606 GN=NDUFAF3 PE=1 SV=1 4.37 2737.2 - 2.01E+06 - - - 0.701 - 2.908 0.672 - 800.3 1 2 0 0.0011 14 0 0 0 1.93E+07 1.43E+07 - - - 6.6828 0.9998 221125_WJC_METTL3_EV_vs_WT_F04.15074.15074.2 0.000662 20-Oct R.LNIPVSQVNPR[166.11].D "sp|P05023|AT1A1_HUMAN,sp|P13637|AT1A3_HUMAN,tr|A0A0A0MT26|A0A0A0MT26_HUMAN,tr|A0A2R8YEY8|A0A2R8YEY8_HUMAN,tr|M0R116|M0R116_HUMAN" 5 1245.7069 1.54 48911 15074 2 1245.708108 623.8607 Sodium\potassium-transporting ATPase subunit alpha-1 OS=Homo sapiens OX=9606 GN=ATP1A1 PE=1 SV=1 9.75 2737.4 - 1.24E+06 - - - 0.9778 - 2.109 0.425 - 336.5 1 2 0 0.0012 11 0 0 0 2.17E+07 1.41E+07 - - - 4.1984 0.9995 221125_WJC_METTL3_EV_vs_WT_F04.15075.15075.3 0.000858 17/44 K.EVEELILTESKK.V "sp|Q9BZZ5|API5_HUMAN,tr|H0YER7|H0YER7_HUMAN,tr|G3V1C3|G3V1C3_HUMAN" 3 1416.7712 4.98 48912 15075 3 1416.768051 473.2643 Apoptosis inhibitor 5 OS=Homo sapiens OX=9606 GN=API5 PE=1 SV=3 4.49 2737.5 - 1.24E+06 - - - -2.2057 - 2.584 0.287 - 355.3 1 2 0 -0.0031 12 0 0 0 1.58E+07 3.18E+06 - - - 4.3703 1 221125_WJC_METTL3_EV_vs_WT_F04.15078.15078.2 0.00224 17/26 K.AVQGAQQPSLYQIR[166.11].T sp|Q13045|FLII_HUMAN 1 1567.8346 1.5 48915 15078 2 1567.829962 784.9246 Protein flightless-1 homolog OS=Homo sapiens OX=9606 GN=FLII PE=1 SV=2 8.79 2737.9 - 832521 - - - -2.9646 - 3.464 0.509 - 849.8 1 2 0 -0.0046 14 0 0 0 1.32E+07 8.80E+06 - - - 5.9168 0.9795 221125_WJC_METTL3_EV_vs_WT_F04.15080.15080.3 0.000779 Nov-56 K.TNGLPVQNGIDADVK.D "sp|Q14671|PUM1_HUMAN,tr|Q5T1Z8|Q5T1Z8_HUMAN,tr|H0YEH2|H0YEH2_HUMAN,tr|Q5T1Z4|Q5T1Z4_HUMAN" 4 1539.7893 2.64 48917 15080 3 1539.778958 514.2704 Pumilio homolog 1 OS=Homo sapiens OX=9606 GN=PUM1 PE=1 SV=3 4.21 2738.1 - 455535 - - - -6.7074 - 2.119 0.314 - 157.7 1 2 0 -0.0103 15 0 0 0 4.23E+06 1.60E+06 - - - 3.9974 1 221125_WJC_METTL3_EV_vs_WT_F04.15082.15082.2 0.000185 24-Dec R.FSGSGSGTDFTLK.L "sp|A2NJV5|KV229_HUMAN,sp|A0A087WW87|KV240_HUMAN,sp|P06310|KV230_HUMAN,sp|A0A075B6S2|KVD29_HUMAN,sp|P01614|KVD40_HUMAN,sp|P01615|KVD28_HUMAN,sp|A0A075B6S6|KVD30_HUMAN,sp|A0A075B6P5|KV228_HUMAN,sp|A0A0A0MRZ7|KVD26_HUMAN" 9 1302.6092 999 48918 15082 2 1302.607404 652.3119 Immunoglobulin kappa variable 2-29 OS=Homo sapiens OX=9606 GN=IGKV2-29 PE=3 SV=2 5.84 2738.3 - 2.05E+08 - - - -1.3757 - 2.597 0.624 - 275.7 1 2 0 -0.0018 13 0 0 0 1.01E+12 0.00E+00 - - - 6.0987 0.9999 221125_WJC_METTL3_EV_vs_WT_F04.15083.15083.3 2.08E-06 13/52 K.TSAALSTVGSAISR.K "sp|O43399|TPD54_HUMAN,tr|A0A087WYR3|A0A087WYR3_HUMAN" 2 1319.7045 1.66 48919 15083 3 1319.701646 440.9088 Tumor protein D54 OS=Homo sapiens OX=9606 GN=TPD52L2 PE=1 SV=2 9.41 2738.4 - 3.12E+06 - - - -2.1581 - 2.597 0.452 - 204.1 1 2 0 -0.0028 14 0 0 0 2.51E+07 1.51E+07 - - - 6.1148 0.9997 221125_WJC_METTL3_EV_vs_WT_F04.15084.15084.3 0.000155 13/52 K.TSAALSTVGSAISR[166.11].K "sp|O43399|TPD54_HUMAN,tr|A0A087WYR3|A0A087WYR3_HUMAN" 2 1329.7128 1.66 48920 15084 3 1329.709707 444.2449 Tumor protein D54 OS=Homo sapiens OX=9606 GN=TPD52L2 PE=1 SV=2 9.41 2738.4 - 2.41E+06 - - - -2.299 - 2.293 0.365 - 202.1 1 2 0 -0.0031 14 0 0 0 2.51E+07 1.51E+07 - - - 4.8139 0.9999 221125_WJC_METTL3_EV_vs_WT_F04.15085.15085.3 0.000178 14/48 K.AIIKPQYVDQIPK.A "sp|P61221|ABCE1_HUMAN,tr|H0Y990|H0Y990_HUMAN,tr|D6RGF4|D6RGF4_HUMAN,tr|D6R9I9|D6R9I9_HUMAN" 4 1511.8712 0.91 48921 15085 3 1511.870292 504.9643 ATP-binding cassette sub-family E member 1 OS=Homo sapiens OX=9606 GN=ABCE1 PE=1 SV=1 8.54 2738.6 - 1.44E+06 - - - -0.5774 - 2.203 0.378 - 222.8 1 2 0 -0.0009 13 0 0 0 2.76E+07 3.03E+07 - - - 4.8955 1 221125_WJC_METTL3_EV_vs_WT_F04.15086.15086.2 5.34E-05 14/26 K.TGQEVVFVAEPDNK.N sp|P04844|RPN2_HUMAN 1 1531.7518 1.03 48922 15086 2 1531.749078 766.8832 Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit 2 OS=Homo sapiens OX=9606 GN=RPN2 PE=1 SV=3 4.14 2738.7 - 1.43E+06 - - - -1.8019 - 3.072 0.532 - 582.2 1 2 0 -0.0028 14 0 0 0 6.45E+07 6.24E+07 - - - 5.7859 1 221125_WJC_METTL3_EV_vs_WT_F04.15087.15087.3 1.23E-05 14/48 K.AIIK[136.11]PQYVDQIPK[136.11].A "sp|P61221|ABCE1_HUMAN,tr|H0Y990|H0Y990_HUMAN,tr|D6RGF4|D6RGF4_HUMAN,tr|D6R9I9|D6R9I9_HUMAN" 4 1527.8996 0.99 48923 15087 3 1527.899414 510.3071 ATP-binding cassette sub-family E member 1 OS=Homo sapiens OX=9606 GN=ABCE1 PE=1 SV=1 8.54 2738.8 - 1.38E+06 - - - -0.0988 - 2.36 0.473 - 190.3 1 2 0 -0.0002 13 0 0 0 2.25E+07 2.28E+07 - - - 6.1415 0.9999 221125_WJC_METTL3_EV_vs_WT_F04.15088.15088.3 9.63E-06 17/56 R.TGFSTSPESPYTHWK[136.11].Q "sp|Q99873|ANM1_HUMAN,tr|E9PKG1|E9PKG1_HUMAN" 2 1731.7984 2.28 48924 15088 3 1731.792133 578.2734 Protein arginine N-methyltransferase 1 OS=Homo sapiens OX=9606 GN=PRMT1 PE=1 SV=3 6.41 2738.9 - 1.25E+06 - - - -3.6194 - 3.082 0.471 - 255.2 1 2 0 -0.0063 15 0 0 0 2.03E+07 8.91E+06 - - - 6.7265 0.9996 221125_WJC_METTL3_EV_vs_WT_F04.15089.15089.2 3.35E-06 20-Nov K.SDITEGVDIPK.K "sp|Q96CB8|INT12_HUMAN,tr|C9J0M6|C9J0M6_HUMAN,tr|A0A087WXN4|A0A087WXN4_HUMAN,tr|E9PGI3|E9PGI3_HUMAN" 4 1172.5925 1.11 48925 15089 2 1172.589725 587.3035 Integrator complex subunit 12 OS=Homo sapiens OX=9606 GN=INTS12 PE=1 SV=1 4.03 2739.1 - 1.17E+06 - - - -2.3529 - 2.448 0.406 - 315.5 1 2 0 -0.0028 11 0 0 0 1.39E+07 1.25E+07 - - - 4.4608 0.9998 221125_WJC_METTL3_EV_vs_WT_F04.15090.15090.2 0.0273 20-Sep K.SDITEGVDIPK[136.11].K "sp|Q96CB8|INT12_HUMAN,tr|C9J0M6|C9J0M6_HUMAN,tr|A0A087WXN4|A0A087WXN4_HUMAN,tr|E9PGI3|E9PGI3_HUMAN" 4 1180.6067 1.14 48926 15090 2 1180.606653 591.3106 Integrator complex subunit 12 OS=Homo sapiens OX=9606 GN=INTS12 PE=1 SV=1 4.03 2739.2 - 1.03E+06 - - - -0.0263 - 2.196 0.362 - 189.4 1 2 0 0 11 0 0 0 1.42E+07 1.25E+07 - - - 3.8428 0.9991 221125_WJC_METTL3_EV_vs_WT_F04.15092.15092.2 0.000359 13/24 R.SPTLYGISHDDLK.G "sp|O75643|U520_HUMAN,tr|A0A494C1A5|A0A494C1A5_HUMAN" 2 1444.7198 2.68 48928 15092 2 1444.714448 723.3672 U5 small nuclear ribonucleoprotein 200 kDa helicase OS=Homo sapiens OX=9606 GN=SNRNP200 PE=1 SV=2 5.19 2739.5 - 800999 - - - -3.7108 - 2.591 0.461 - 528.1 1 2 0 -0.0054 13 0 0 0 7.14E+06 2.66E+06 - - - 4.8877 1 221125_WJC_METTL3_EV_vs_WT_F04.15098.15098.3 1.15E-06 15/48 R.EQDLPLAEAVRPK.T sp|Q96A49|SYAP1_HUMAN 1 1464.7936 4.71 48933 15098 3 1464.791992 489.2718 Synapse-associated protein 1 OS=Homo sapiens OX=9606 GN=SYAP1 PE=1 SV=1 4.68 2740.1 - 2.28E+07 - - - -1.1271 - 2.524 0.519 - 378.8 1 2 0 -0.0017 13 0 0 0 3.52E+09 7.48E+08 - - - 6.8361 0.9995 221125_WJC_METTL3_EV_vs_WT_F04.15101.15101.3 0.000549 Nov-40 K.WGR[166.11]DDIENIAR[166.11].E sp|O60264|SMCA5_HUMAN 1 1363.6748 1.41 48936 15101 3 1363.672039 455.5655 SWI\SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A member 5 OS=Homo sapiens OX=9606 GN=SMARCA5 PE=1 SV=1 4.56 2740.3 - 1.72E+06 - - - -1.9895 - 2.443 0.417 - 247.1 1 2 1 -0.0027 11 0 0 0 9.49E+06 6.72E+06 - - - 5.7259 1 221125_WJC_METTL3_EV_vs_WT_F04.15103.15103.3 2.79E-09 26/64 K.IPYSDVNIGTGVAHPPR.W "sp|Q9UKM7|MA1B1_HUMAN,tr|A0A804HK28|A0A804HK28_HUMAN,tr|H0YG20|H0YG20_HUMAN,tr|A0A804HKS1|A0A804HKS1_HUMAN,tr|H0YGV7|H0YGV7_HUMAN,tr|A0A804HL65|A0A804HL65_HUMAN,tr|A0A804HIP1|A0A804HIP1_HUMAN,tr|A0A804HK01|A0A804HK01_HUMAN,tr|A0A804HJ23|A0A804HJ23_HUMAN,tr|A0A804HHU1|A0A804HHU1_HUMAN,tr|A0A804HK86|A0A804HK86_HUMAN,tr|A0A804HL61|A0A804HL61_HUMAN,tr|A0A804HJ66|A0A804HJ66_HUMAN,tr|H0YGQ1|H0YGQ1_HUMAN,tr|H0YI64|H0YI64_HUMAN,tr|A0A804HJW0|A0A804HJW0_HUMAN" 16 1791.9268 2.62 48938 15103 3 1791.930908 598.3162 "Endoplasmic reticulum mannosyl-oligosaccharide 1,2-alpha-mannosidase OS=Homo sapiens OX=9606 GN=MAN1B1 PE=1 SV=2" 6.74 2740.6 - 1.26E+06 - - - 2.3025 - 3.435 0.59 - 666 1 2 0 0.0041 17 0 0 0 1.03E+07 3.95E+06 - - - 8.2343 1 221125_WJC_METTL3_EV_vs_WT_F04.15104.15104.3 1.42E-05 13/56 R.VFLQDHC[160.03]LAEGYGTK[136.11].K sp|O15226|NKRF_HUMAN 1 1744.8334 0.96 48939 15104 3 1744.833736 582.6184 NF-kappa-B-repressing factor OS=Homo sapiens OX=9606 GN=NKRF PE=1 SV=2 5.32 2740.7 - 1.22E+06 - - - 0.1891 - 2.233 0.474 - 170.5 1 2 0 0.0003 15 0 0 0 1.08E+07 1.13E+07 - - - 5.9208 1 221125_WJC_METTL3_EV_vs_WT_F04.15108.15108.3 3.15E-06 19/52 R.LGYFSVDPDSHQGK.L "sp|P47897|SYQ_HUMAN,tr|B4DDN1|B4DDN1_HUMAN,tr|A0A0U1RR79|A0A0U1RR79_HUMAN,tr|A0A1B0GVU9|A0A1B0GVU9_HUMAN" 4 1548.7209 1.17 48943 15108 3 1548.720507 517.2476 Glutamine--tRNA ligase OS=Homo sapiens OX=9606 GN=QARS1 PE=1 SV=1 5.21 2741.2 - 645067 - - - -0.2357 - 2.693 0.546 - 380.6 1 2 0 -0.0004 14 0 0 0 1.31E+07 1.12E+07 - - - 7.26 0.9998 221125_WJC_METTL3_EV_vs_WT_F04.15110.15110.3 0.00467 15/52 R.LGYFSVDPDSHQGK[136.11].L "sp|P47897|SYQ_HUMAN,tr|B4DDN1|B4DDN1_HUMAN,tr|A0A0U1RR79|A0A0U1RR79_HUMAN,tr|A0A1B0GVU9|A0A1B0GVU9_HUMAN" 4 1556.7351 1.17 48945 15110 3 1556.737343 519.919 Glutamine--tRNA ligase OS=Homo sapiens OX=9606 GN=QARS1 PE=1 SV=1 5.21 2741.5 - 621360 - - - 1.4588 - 2.361 0.385 - 211.5 1 2 0 0.0023 14 0 0 0 1.31E+07 1.12E+07 - - - 5.1148 0.9999 221125_WJC_METTL3_EV_vs_WT_F04.15111.15111.2 2.12E-09 22-Nov K.VLNEEC[160.03]DQNWYK[136.11].A "sp|P62993|GRB2_HUMAN,tr|J3QRL5|J3QRL5_HUMAN,tr|J3KT38|J3KT38_HUMAN" 3 1604.7021 0.83 48946 15111 2 1604.699947 803.3583 Growth factor receptor-bound protein 2 OS=Homo sapiens OX=9606 GN=GRB2 PE=1 SV=1 4.14 2741.6 - 599119 - - - -1.3155 - 2.313 0.542 - 399.7 1 2 0 -0.0021 12 0 0 0 3.10E+06 3.72E+06 - - - 5.2499 0.9962 221125_WJC_METTL3_EV_vs_WT_F04.15112.15112.4 0.0244 Nov-72 K.IWVPVDHRPSLPR.S "sp|Q16875|F263_HUMAN,tr|A0A1W2PR17|A0A1W2PR17_HUMAN,tr|Q5W015|Q5W015_HUMAN,tr|F2Z2I2|F2Z2I2_HUMAN,tr|Q5VX20|Q5VX20_HUMAN" 5 1570.8732 8.65 48947 15112 4 1570.870062 393.7256 "6-phosphofructo-2-kinase\fructose-2,6-bisphosphatase 3 OS=Homo sapiens OX=9606 GN=PFKFB3 PE=1 SV=1" 9.61 2741.7 - 510897 - - - -2.0173 - 2.229 0.247 - 80.2 1 2 0 -0.0032 13 0 0 0 1.42E+06 1.64E+05 - - - 1.6722 0.837 221125_WJC_METTL3_EV_vs_WT_F04.15113.15113.2 3.26E-06 16-Nov M.VNHFIAEFK[136.11].R "sp|P11142|HSP7C_HUMAN,tr|A8K7Q2|A8K7Q2_HUMAN,tr|E9PKE3|E9PKE3_HUMAN,tr|E9PN89|E9PN89_HUMAN" 4 1111.5906 0.09 48948 15113 2 1111.59633 556.8026 Heat shock cognate 71 kDa protein OS=Homo sapiens OX=9606 GN=HSPA8 PE=1 SV=1 6.72 2741.9 - 439509 - - - 5.1728 - 2.091 0.458 - 437 1 1 0 0.0057 9 0 0 0 5.42E+05 6.31E+06 - - - 4.556 1 221125_WJC_METTL3_EV_vs_WT_F04.15116.15116.3 4.24E-05 15/52 K.TVPEELVK[136.11]PEELSK[136.11].Y "sp|Q9UMS4|PRP19_HUMAN,tr|H0YGF3|H0YGF3_HUMAN,tr|F5GY56|F5GY56_HUMAN" 3 1612.8895 1.41 48950 15116 3 1612.887016 538.6371 Pre-mRNA-processing factor 19 OS=Homo sapiens OX=9606 GN=PRPF19 PE=1 SV=1 4.49 2742.3 - 1.98E+06 - - - -1.5116 - 2.435 0.513 - 190.4 1 2 0 -0.0024 14 0 0 0 1.20E+09 8.51E+08 - - - 6.6238 1 221125_WJC_METTL3_EV_vs_WT_F04.15118.15118.3 1.09E-09 18/52 R.LDDTVHVVIATPGR[166.11].L sp|P26196|DDX6_HUMAN 1 1501.8128 1.07 48951 15118 3 1501.811047 501.6115 Probable ATP-dependent RNA helicase DDX6 OS=Homo sapiens OX=9606 GN=DDX6 PE=1 SV=2 5.21 2742.5 - 3.93E+06 - - - -1.1752 - 2.882 0.586 - 559.8 1 2 0 -0.0018 14 0 0 0 1.54E+08 1.44E+08 - - - 7.8858 1 221125_WJC_METTL3_EV_vs_WT_F04.15119.15119.3 2.74E-08 15/52 R.LDDTVHVVIATPGR.L sp|P26196|DDX6_HUMAN 1 1491.8045 1.06 48952 15119 3 1491.802013 498.2755 Probable ATP-dependent RNA helicase DDX6 OS=Homo sapiens OX=9606 GN=DDX6 PE=1 SV=2 5.21 2742.5 - 4.44E+06 - - - -1.6953 - 2.588 0.581 - 272.1 1 2 0 -0.0025 14 0 0 0 1.54E+08 1.45E+08 - - - 7.5439 0.9867 221125_WJC_METTL3_EV_vs_WT_F04.15120.15120.2 0.00213 18-Aug R.SIFQHIQSAQ.S "sp|Q9Y2W1|TR150_HUMAN,tr|A0A3B3ITZ9|A0A3B3ITZ9_HUMAN" 2 1157.5829 - 48953 15120 2 1157.5824 579.7987 Thyroid hormone receptor-associated protein 3 OS=Homo sapiens OX=9606 GN=THRAP3 PE=1 SV=2 6.46 2742.6 - 5.66E+06 - - - -0.4509 - 1.846 0.434 - 184.6 1 1 0 -0.0005 10 0 0 0 - - - - - 3.9575 1 221125_WJC_METTL3_EV_vs_WT_F04.15121.15121.3 2.04E-05 15/56 R.IPMSLGEPHAELDAK.G "sp|Q9NWS0|PIHD1_HUMAN,tr|M0QYF4|M0QYF4_HUMAN,tr|M0R3A4|M0R3A4_HUMAN,tr|M0R3A8|M0R3A8_HUMAN,tr|M0R028|M0R028_HUMAN,tr|M0QZM3|M0QZM3_HUMAN,tr|M0R1R3|M0R1R3_HUMAN,tr|M0QYA2|M0QYA2_HUMAN" 8 1606.8025 1.67 48954 15121 3 1606.80247 536.6081 PIH1 domain-containing protein 1 OS=Homo sapiens OX=9606 GN=PIH1D1 PE=1 SV=1 4.65 2742.6 - 2.15E+06 - - - -0.0143 - 3.129 0.531 - 296 1 2 0 0 15 0 0 0 9.08E+07 5.45E+07 - - - 7.4367 0.9994 221125_WJC_METTL3_EV_vs_WT_F04.15122.15122.3 0.000894 Nov-40 K.TKTDELLALGR.E sp|P12270|TPR_HUMAN 1 1215.6823 2.7 48955 15122 3 1215.681364 406.2347 Nucleoprotein TPR OS=Homo sapiens OX=9606 GN=TPR PE=1 SV=3 5.74 2742.7 - 1.67E+06 - - - -0.7716 - 2.177 0.371 - 148 1 2 1 -0.0009 11 0 0 0 1.46E+07 5.42E+06 - - - 4.886 0.9999 221125_WJC_METTL3_EV_vs_WT_F04.15123.15123.3 0.000157 14/56 R.IPMSLGEPHAELDAK[136.11].G "sp|Q9NWS0|PIHD1_HUMAN,tr|M0QYF4|M0QYF4_HUMAN,tr|M0R3A4|M0R3A4_HUMAN,tr|M0R3A8|M0R3A8_HUMAN,tr|M0R028|M0R028_HUMAN,tr|M0QZM3|M0QZM3_HUMAN,tr|M0R1R3|M0R1R3_HUMAN,tr|M0QYA2|M0QYA2_HUMAN" 8 1614.8167 1.64 48956 15123 3 1614.816725 539.2795 PIH1 domain-containing protein 1 OS=Homo sapiens OX=9606 GN=PIH1D1 PE=1 SV=1 4.65 2742.8 - 1.62E+06 - - - 0.0198 - 2.153 0.39 - 123.5 1 2 0 0 15 0 0 0 8.92E+07 5.44E+07 - - - 4.8891 0.9999 221125_WJC_METTL3_EV_vs_WT_F04.15124.15124.3 0.000145 15/48 R.GAPVIVPELGKPR.Q "sp|Q9Y618|NCOR2_HUMAN,tr|C9J7T7|C9J7T7_HUMAN,tr|C9JE98|C9JE98_HUMAN,tr|C9J0Q5|C9J0Q5_HUMAN,tr|A0A384DVL6|A0A384DVL6_HUMAN" 5 1331.7925 2.53 48957 15124 3 1331.790675 444.9381 Nuclear receptor corepressor 2 OS=Homo sapiens OX=9606 GN=NCOR2 PE=1 SV=3 8.75 2742.9 - 1.53E+06 - - - -1.3861 - 2.467 0.422 - 324.3 1 2 0 -0.0018 13 0 0 0 1.13E+07 4.48E+06 - - - 5.6927 0.9999 221125_WJC_METTL3_EV_vs_WT_F04.15126.15126.2 3.12E-06 18/28 R.SSLGSLQTPEAVTTR[166.11].K "sp|Q7Z2W4|ZCCHV_HUMAN,tr|C9J6P4|C9J6P4_HUMAN,tr|A0A7P0T8C6|A0A7P0T8C6_HUMAN" 3 1555.8081 1.6 48959 15126 2 1555.807497 778.9113 Zinc finger CCCH-type antiviral protein 1 OS=Homo sapiens OX=9606 GN=ZC3HAV1 PE=1 SV=3 5.72 2743.1 - 1.14E+06 - - - -0.4011 - 3.294 0.489 - 947 1 2 0 -0.0006 15 0 0 0 2.00E+07 1.25E+07 - - - 5.5834 0.9994 221125_WJC_METTL3_EV_vs_WT_F04.15127.15127.3 0.000153 14/40 R.GYAFIEYEHER[166.11].D "sp|P08621|RU17_HUMAN,tr|M0QYR1|M0QYR1_HUMAN" 2 1422.6444 1.69 48960 15127 3 1422.637824 475.2221 U1 small nuclear ribonucleoprotein 70 kDa OS=Homo sapiens OX=9606 GN=SNRNP70 PE=1 SV=2 4.75 2743.2 - 784361 - - - -4.5872 - 1.866 0.5 - 244.1 1 2 0 -0.0065 11 0 0 0 1.13E+07 6.70E+06 - - - 5.8848 0.9994 221125_WJC_METTL3_EV_vs_WT_F04.15128.15128.3 0.00119 Dec-40 K.TK[136.11]TDELLALGR[166.11].E sp|P12270|TPR_HUMAN 1 1233.7048 2.8 48961 15128 3 1233.705871 412.2422 Nucleoprotein TPR OS=Homo sapiens OX=9606 GN=TPR PE=1 SV=3 5.74 2743.3 - 568320 - - - 0.8908 - 2.246 0.372 - 194.7 1 2 1 0.0011 11 0 0 0 1.41E+07 5.04E+06 - - - 4.9858 0.9922 221125_WJC_METTL3_EV_vs_WT_F04.15129.15129.2 0.000159 13/24 K.TNQVAIAQTLEC[160.03]K.E sp|Q9UK39|NOCT_HUMAN 1 1474.745 0.24 48962 15129 2 1474.748841 738.3798 Nocturnin OS=Homo sapiens OX=9606 GN=NOCT PE=1 SV=2 5.66 2743.4 - 535719 - - - 2.6188 - 2.076 0.107 - 424.9 1 2 0 0.0039 13 0 0 0 7.12E+06 2.97E+07 - - - 1.7048 1 221125_WJC_METTL3_EV_vs_WT_F04.15131.15131.2 2.06E-06 16/24 K.GIHPTIISESFQK.A sp|P50991|TCPD_HUMAN 1 1455.7722 0.16 48964 15131 2 1455.775342 728.8934 T-complex protein 1 subunit delta OS=Homo sapiens OX=9606 GN=CCT4 PE=1 SV=4 6.75 2743.7 - 471685 - - - 2.1727 - 3.089 0.569 - 573.6 1 2 0 0.0032 13 0 0 0 4.42E+07 2.68E+08 - - - 6.1373 0.9999 221125_WJC_METTL3_EV_vs_WT_F04.15133.15133.2 2.71E-09 30-Aug R.FQDVGPQAPVGSVYQK[136.11].T "sp|Q9UJU6|DBNL_HUMAN,tr|H0Y5J4|H0Y5J4_HUMAN,tr|B4DDD6|B4DDD6_HUMAN" 3 1726.877 1.07 48966 15133 2 1726.877799 864.4458 Drebrin-like protein OS=Homo sapiens OX=9606 GN=DBNL PE=1 SV=1 5.83 2743.9 - 297706 - - - 0.4714 - 1.883 0.631 - 151.9 1 2 0 0.0008 16 0 0 0 1.58E+06 1.49E+06 - - - 5.2572 1 221125_WJC_METTL3_EV_vs_WT_F04.15135.15135.2 3.74E-07 20-Nov R.NPEAALSPTFR[166.11].S "sp|Q86U44|MTA70_HUMAN,tr|B4E349|B4E349_HUMAN,tr|F5H6D8|F5H6D8_HUMAN,tr|B4DTN4|B4DTN4_HUMAN" 4 1211.6174 0.02 48967 15135 2 1211.617012 606.816 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 6 2744.2 - 8.20E+06 - - - -0.326 - 2.535 0.567 - 672.7 1 2 0 -0.0004 11 0 0 0 1.67E+08 1.05E+10 - - - 5.7451 0.9998 221125_WJC_METTL3_EV_vs_WT_F04.15137.15137.3 0.00889 Dec-48 K.GIHPTIISESFQK.A sp|P50991|TCPD_HUMAN 1 1455.7722 0.17 48968 15137 3 1455.771606 486.2647 T-complex protein 1 subunit delta OS=Homo sapiens OX=9606 GN=CCT4 PE=1 SV=4 6.75 2744.4 - 9.40E+06 - - - -0.3936 - 2.089 0.382 - 251 1 2 0 -0.0006 13 0 0 0 2.85E+08 1.71E+09 - - - 4.7961 0.9998 221125_WJC_METTL3_EV_vs_WT_F04.15138.15138.2 0.00214 24-Nov K.IAQLEEQLDNETK.E sp|P35579|MYH9_HUMAN 1 1529.7573 0.96 48969 15138 2 1529.756287 765.8859 Myosin-9 OS=Homo sapiens OX=9606 GN=MYH9 PE=1 SV=4 4 2744.4 - 4.53E+06 - - - -0.6733 - 2.496 0.4 - 455.1 1 2 0 -0.001 13 0 0 0 1.73E+08 1.80E+08 - - - 4.3427 1 221125_WJC_METTL3_EV_vs_WT_F04.15139.15139.3 0.243 18/52 K.AQIHDLVLVGGSTR[166.11].L "sp|P0DMV8|HS71A_HUMAN,sp|P0DMV9|HS71B_HUMAN,tr|V9GZ37|V9GZ37_HUMAN,tr|A0A0G2JIW1|A0A0G2JIW1_HUMAN" 4 1474.8131 0.27 48970 15139 3 1474.811177 492.6117 Heat shock 70 kDa protein 1A OS=Homo sapiens OX=9606 GN=HSPA1A PE=1 SV=1 6.79 2744.5 - 4.77E+06 - - - -1.3351 - 2.777 0.458 - 387.7 1 2 0 -0.002 14 0 0 0 3.06E+09 1.13E+10 - - - 6.36 0.9998 221125_WJC_METTL3_EV_vs_WT_F04.15140.15140.2 0.0152 26-Oct R.GQAGFFSTPGGASR.D sp|Q8IYI6|EXOC8_HUMAN 1 1338.6317 1.78 48971 15140 2 1338.63113 670.3231 Exocyst complex component 8 OS=Homo sapiens OX=9606 GN=EXOC8 PE=1 SV=2 9.75 2744.5 - 2.83E+06 - - - -0.3982 - 2.323 0.436 - 338.3 1 2 0 -0.0005 14 0 0 0 5.75E+07 3.22E+07 - - - 4.3762 0.9999 221125_WJC_METTL3_EV_vs_WT_F04.15141.15141.2 2.84E-05 13/26 R.GQAGFFSTPGGASR[166.11].D sp|Q8IYI6|EXOC8_HUMAN 1 1348.6399 1.78 48972 15141 2 1348.63988 675.3272 Exocyst complex component 8 OS=Homo sapiens OX=9606 GN=EXOC8 PE=1 SV=2 9.75 2744.6 - 1.75E+06 - - - -0.0393 - 2.587 0.457 - 575.7 1 2 0 -0.0001 14 0 0 0 5.73E+07 3.22E+07 - - - 4.8016 1 221125_WJC_METTL3_EV_vs_WT_F04.15142.15142.3 4.67E-05 18/56 K.YLQTVQYGVHGNFPR.L "sp|Q14527|HLTF_HUMAN,tr|A0A0C4DGA6|A0A0C4DGA6_HUMAN" 2 1777.89 1.21 48973 15142 3 1777.890754 593.6373 Helicase-like transcription factor OS=Homo sapiens OX=9606 GN=HLTF PE=1 SV=2 8.6 2744.7 - 1.42E+06 - - - 0.4224 - 3.084 0.531 - 323.2 1 2 0 0.0008 15 0 0 0 1.02E+07 8.37E+06 - - - 7.3987 1 221125_WJC_METTL3_EV_vs_WT_F04.15143.15143.3 1.36E-06 15/40 R.GYAFIEYEHER.D "sp|P08621|RU17_HUMAN,tr|M0QYR1|M0QYR1_HUMAN" 2 1412.6361 1.69 48974 15143 3 1412.634434 471.886 U1 small nuclear ribonucleoprotein 70 kDa OS=Homo sapiens OX=9606 GN=SNRNP70 PE=1 SV=2 4.75 2744.8 - 1.37E+06 - - - -1.1652 - 2.642 0.485 - 259.7 1 2 0 -0.0016 11 0 0 0 1.13E+07 6.70E+06 - - - 6.7068 0.9977 221125_WJC_METTL3_EV_vs_WT_F04.15146.15146.3 0.0171 Sep-44 R.DGWPAMGIHGDK.S "sp|P17844|DDX5_HUMAN,tr|A0A7I2V5F5|A0A7I2V5F5_HUMAN,tr|A0A7I2V507|A0A7I2V507_HUMAN,tr|J3KTA4|J3KTA4_HUMAN,tr|A0A0G2JLI4|A0A0G2JLI4_HUMAN,tr|A0A7I2V2S0|A0A7I2V2S0_HUMAN" 6 1282.5765 1.55 48977 15146 3 1282.574546 428.5328 Probable ATP-dependent RNA helicase DDX5 OS=Homo sapiens OX=9606 GN=DDX5 PE=1 SV=1 5.21 2745.2 - 398467 - - - -1.4892 - 1.616 0.273 - 63.8 1 2 0 -0.0019 12 0 0 0 1.20E+08 7.70E+07 - - - 2.9135 1 221125_WJC_METTL3_EV_vs_WT_F04.15148.15148.2 2.82E-10 16/26 R.LDDTVHVVIATPGR[166.11].L sp|P26196|DDX6_HUMAN 1 1501.8128 1.21 48979 15148 2 1501.813797 751.9137 Probable ATP-dependent RNA helicase DDX6 OS=Homo sapiens OX=9606 GN=DDX6 PE=1 SV=2 5.21 2745.5 - 279455 - - - 0.6559 - 2.895 0.561 - 944.1 1 2 0 0.001 14 0 0 0 6.95E+06 5.76E+06 - - - 5.8517 0.9999 221125_WJC_METTL3_EV_vs_WT_F04.15154.15154.2 3.28E-05 14/24 K.IAQLEEQLDNETK[136.11].E sp|P35579|MYH9_HUMAN 1 1537.7715 1 48983 15154 2 1537.770281 769.893 Myosin-9 OS=Homo sapiens OX=9606 GN=MYH9 PE=1 SV=4 4 2746.3 - 8.10E+06 - - - -0.8038 - 2.935 0.522 - 786.9 1 2 0 -0.0012 13 0 0 0 1.73E+08 1.73E+08 - - - 5.6595 0.9996 221125_WJC_METTL3_EV_vs_WT_F04.15155.15155.3 0.000548 Nov-48 K.IAQLEEQLDNETK.E sp|P35579|MYH9_HUMAN 1 1529.7573 0.72 48984 15155 3 1529.756619 510.9264 Myosin-9 OS=Homo sapiens OX=9606 GN=MYH9 PE=1 SV=4 4 2746.3 - 2.72E+06 - - - -0.4563 - 1.953 0.33 - 172.8 1 2 0 -0.0007 13 0 0 0 2.16E+07 2.99E+07 - - - 4.0338 0.9999 221125_WJC_METTL3_EV_vs_WT_F04.15156.15156.2 2.55E-05 13/24 R.AQVDDLTEAVAAK.D sp|Q8TBA6|GOGA5_HUMAN 1 1329.6776 2.34 48985 15156 2 1329.67564 665.8461 Golgin subfamily A member 5 OS=Homo sapiens OX=9606 GN=GOLGA5 PE=1 SV=3 4.03 2746.4 - 2.22E+06 - - - -1.4816 - 2.554 0.541 - 481.7 1 2 0 -0.002 13 0 0 0 2.97E+07 1.27E+07 - - - 5.4427 1 221125_WJC_METTL3_EV_vs_WT_F04.15159.15159.2 8.46E-05 16/26 K.AQIHDLVLVGGSTR[166.11].L "sp|P0DMV8|HS71A_HUMAN,sp|P0DMV9|HS71B_HUMAN,tr|V9GZ37|V9GZ37_HUMAN,tr|A0A0G2JIW1|A0A0G2JIW1_HUMAN" 4 1474.8131 0.17 48988 15159 2 1474.812778 738.4138 Heat shock 70 kDa protein 1A OS=Homo sapiens OX=9606 GN=HSPA1A PE=1 SV=1 6.79 2746.6 - 1.68E+06 - - - -0.2495 - 2.957 0.65 - 914.6 1 2 0 -0.0004 14 0 0 0 1.90E+08 1.13E+09 - - - 6.5625 0.9999 221125_WJC_METTL3_EV_vs_WT_F04.15160.15160.3 0.0999 13/40 K.AEVVLGNIIKK.K "sp|Q13303|KCAB2_HUMAN,tr|K7EKU4|K7EKU4_HUMAN,tr|A0A590UJV4|A0A590UJV4_HUMAN,tr|A0A590UJJ4|A0A590UJJ4_HUMAN,tr|Q5TG78|Q5TG78_HUMAN,tr|A0A590UJY1|A0A590UJY1_HUMAN,tr|K7EIR5|K7EIR5_HUMAN,tr|A0A590UJB8|A0A590UJB8_HUMAN,tr|Q5TG84|Q5TG84_HUMAN,tr|A0A590UK89|A0A590UK89_HUMAN,tr|Q5TG81|Q5TG81_HUMAN,tr|A0A5F9UN28|A0A5F9UN28_HUMAN,tr|A0A590UJU1|A0A590UJU1_HUMAN,tr|A0A590UJB6|A0A590UJB6_HUMAN,tr|A0A590UJU4|A0A590UJU4_HUMAN" 15 1182.7336 1.75 48989 15160 3 1182.73272 395.2518 Voltage-gated potassium channel subunit beta-2 OS=Homo sapiens OX=9606 GN=KCNAB2 PE=1 SV=2 8.64 2746.7 - 1.39E+06 - - - -0.7516 - 2.588 0.394 - 193.2 1 2 0 -0.0009 11 0 0 0 1.40E+07 7.99E+06 - - - 5.6338 0.9999 221125_WJC_METTL3_EV_vs_WT_F04.15161.15161.3 0.00136 14/48 R.ATFQVEHLGTGLK.E sp|Q8IWI9|MGAP_HUMAN 1 1399.746 0.59 48990 15161 3 1399.745713 467.5893 MAX gene-associated protein OS=Homo sapiens OX=9606 GN=MGA PE=1 SV=4 6.79 2746.9 - 1.32E+06 - - - -0.18 - 2.452 0.348 - 188.9 1 2 0 -0.0003 13 0 0 0 1.77E+07 2.98E+07 - - - 4.8516 0.9999 221125_WJC_METTL3_EV_vs_WT_F04.15162.15162.2 2.53E-07 15/28 R.SSLGSLQTPEAVTTR.K "sp|Q7Z2W4|ZCCHV_HUMAN,tr|C9J6P4|C9J6P4_HUMAN,tr|A0A7P0T8C6|A0A7P0T8C6_HUMAN" 3 1545.7999 1.6 48991 15162 2 1545.798331 773.9072 Zinc finger CCCH-type antiviral protein 1 OS=Homo sapiens OX=9606 GN=ZC3HAV1 PE=1 SV=3 5.72 2747 - 1.27E+06 - - - -0.9833 - 3.098 0.421 - 594.3 1 2 0 -0.0015 15 0 0 0 2.00E+07 1.25E+07 - - - 4.93 1 221125_WJC_METTL3_EV_vs_WT_F04.15164.15164.3 1.51E-07 22/60 R.VSNFK[136.11]PGVYAVSVTGR[166.11].L "sp|P63272|SPT4H_HUMAN,tr|D3DTZ5|D3DTZ5_HUMAN,tr|J3QSB9|J3QSB9_HUMAN" 3 1697.922 1.98 48993 15164 3 1697.919886 566.9813 Transcription elongation factor SPT4 OS=Homo sapiens OX=9606 GN=SUPT4H1 PE=1 SV=1 9.99 2747.3 - 1.15E+06 - - - -1.2303 - 3.14 0.551 - 606.7 1 2 0 -0.0021 16 0 0 0 2.86E+07 1.45E+07 - - - 7.6184 1 221125_WJC_METTL3_EV_vs_WT_F04.15165.15165.2 1.06E-06 16/28 R.ISVATGALEAAQGSK[136.11].S "sp|P51610|HCFC1_HUMAN,tr|A6NEM2|A6NEM2_HUMAN" 2 1409.7606 0.49 48994 15165 2 1409.761519 705.8876 Host cell factor 1 OS=Homo sapiens OX=9606 GN=HCFC1 PE=1 SV=2 6 2747.4 - 736251 - - - 0.6817 - 3.227 0.536 - 1036.1 1 2 0 0.001 15 0 0 0 4.75E+06 9.75E+06 - - - 5.8799 0.9882 221125_WJC_METTL3_EV_vs_WT_F04.15167.15167.3 0.111 Oct-36 R.WK[136.11]DYLPVGQR[166.11].M "sp|O75319|DUS11_HUMAN,tr|H7C0E6|H7C0E6_HUMAN" 2 1278.684 0.63 48996 15167 3 1278.687069 427.2353 RNA\RNP complex-1-interacting phosphatase OS=Homo sapiens OX=9606 GN=DUSP11 PE=1 SV=2 8.59 2747.6 - 613815 - - - 2.4181 - 2.128 0.229 - 210.4 1 2 1 0.0031 10 0 0 0 9.94E+06 1.59E+07 - - - 3.2977 0.9998 221125_WJC_METTL3_EV_vs_WT_F04.15168.15168.2 2.02E-06 20-Dec R.DMSDNVLYQNR.N sp|Q7Z353|HDX_HUMAN 1 1353.5983 9.47 48997 15168 2 1353.599576 677.8064 Highly divergent homeobox OS=Homo sapiens OX=9606 GN=HDX PE=1 SV=1 4.21 2747.8 - 577117 - - - 0.9323 - 1.956 0.512 - 396.2 1 2 0 0.0013 11 0 0 0 6.91E+06 7.29E+05 - - - 4.6372 0.9998 221125_WJC_METTL3_EV_vs_WT_F04.15169.15169.2 3.83E-05 14/16 R.R[166.11]SDSLLSFR[166.11].L sp|Q00587|BORG5_HUMAN 1 1099.5889 1.64 48998 15169 2 1099.587558 550.8017 Cdc42 effector protein 1 OS=Homo sapiens OX=9606 GN=CDC42EP1 PE=1 SV=1 9.6 2747.9 - 529942 - - - -1.2177 - 2.287 0.427 - 453.2 1 2 0 -0.0013 9 0 0 0 1.77E+07 1.08E+07 - - - 4.5877 1 221125_WJC_METTL3_EV_vs_WT_F04.15170.15170.2 5.00E-09 13/26 L.YTIDTENSTVALAK.V "sp|Q8ND56|LS14A_HUMAN,tr|I3L4Q1|I3L4Q1_HUMAN,tr|A0A140TA76|A0A140TA76_HUMAN,tr|K7EMZ9|K7EMZ9_HUMAN" 4 1524.7672 17.22 48999 15170 2 1524.769134 763.3909 Protein LSM14 homolog A OS=Homo sapiens OX=9606 GN=LSM14A PE=1 SV=3 4.37 2748 - 397988 - - - 1.2986 - 2.597 0.694 - 571.1 1 1 0 0.002 14 0 0 0 5.89E+06 3.42E+05 - - - 6.5612 0.9999 221125_WJC_METTL3_EV_vs_WT_F04.15173.15173.3 1.98E-06 17/52 K.TVPEELVKPEELSK.Y "sp|Q9UMS4|PRP19_HUMAN,tr|H0YGF3|H0YGF3_HUMAN,tr|F5GY56|F5GY56_HUMAN" 3 1596.8611 1.82 49001 15173 3 1596.859982 533.2943 Pre-mRNA-processing factor 19 OS=Homo sapiens OX=9606 GN=PRPF19 PE=1 SV=1 4.49 2748.4 - 1.44E+06 - - - -0.6713 - 2.398 0.355 - 225.8 1 2 0 -0.0011 14 0 0 0 2.48E+07 1.36E+07 - - - 4.822 1 221125_WJC_METTL3_EV_vs_WT_F04.15176.15176.2 1.62E-05 15/24 K.GIHPTIISESFQK[136.11].A sp|P50991|TCPD_HUMAN 1 1463.7864 0.16 49003 15176 2 1463.785315 732.9005 T-complex protein 1 subunit delta OS=Homo sapiens OX=9606 GN=CCT4 PE=1 SV=4 6.75 2748.6 - 1.32E+07 - - - -0.7269 - 2.789 0.575 - 531.5 1 2 0 -0.0011 13 0 0 0 4.42E+07 2.78E+08 - - - 5.9201 0.9999 221125_WJC_METTL3_EV_vs_WT_F04.15177.15177.2 8.70E-07 13/20 R.QLQNIIQATSR.E sp|P15924|DESP_HUMAN 1 1270.6993 28.64 49004 15177 2 1270.699169 636.357 Desmoplakin OS=Homo sapiens OX=9606 GN=DSP PE=1 SV=3 9.75 2748.6 - 6.03E+06 - - - -0.1417 - 2.488 0.544 - 793.3 1 2 0 -0.0002 11 0 0 0 2.16E+08 7.54E+06 - - - 5.5247 1 221125_WJC_METTL3_EV_vs_WT_F04.15178.15178.3 1.82E-06 17/60 R.VSNFKPGVYAVSVTGR.L "sp|P63272|SPT4H_HUMAN,tr|D3DTZ5|D3DTZ5_HUMAN,tr|J3QSB9|J3QSB9_HUMAN" 3 1679.8995 1.96 49005 15178 3 1679.898629 560.9738 Transcription elongation factor SPT4 OS=Homo sapiens OX=9606 GN=SUPT4H1 PE=1 SV=1 9.99 2748.7 - 2.78E+06 - - - -0.5215 - 2.996 0.525 - 331.8 1 2 0 -0.0009 16 0 0 0 2.88E+07 1.47E+07 - - - 7.2085 1 221125_WJC_METTL3_EV_vs_WT_F04.15183.15183.2 1.33E-11 16/28 K.FSNQETC[160.03]VEIGESVR.G "sp|P60891|PRPS1_HUMAN,tr|A0A2R8Y7H4|A0A2R8Y7H4_HUMAN,tr|A0A6Q8PHK9|A0A6Q8PHK9_HUMAN,tr|B1ALA9|B1ALA9_HUMAN,tr|B1ALA7|B1ALA7_HUMAN" 5 1753.7941 0.68 49010 15183 2 1753.793565 877.9043 Ribose-phosphate pyrophosphokinase 1 OS=Homo sapiens OX=9606 GN=PRPS1 PE=1 SV=2 4.25 2749.2 - 618011 - - - -0.313 - 3.075 0.647 - 1072.2 1 2 0 -0.0005 15 0 0 0 1.39E+07 2.03E+07 - - - 6.5813 0.9994 221125_WJC_METTL3_EV_vs_WT_F04.15184.15184.2 1.92E-06 13/26 R.LDDTVHVVIATPGR.L sp|P26196|DDX6_HUMAN 1 1491.8045 1.29 49011 15184 2 1491.7993 746.9095 Probable ATP-dependent RNA helicase DDX6 OS=Homo sapiens OX=9606 GN=DDX6 PE=1 SV=2 5.21 2749.3 - 604962 - - - -3.5139 - 2.799 0.501 - 547.6 1 2 0 -0.0052 14 0 0 0 7.45E+06 5.76E+06 - - - 5.3226 1 221125_WJC_METTL3_EV_vs_WT_F04.15185.15185.2 1.99E-09 13/26 R.GYTASSLDSSSSWR.E "sp|Q5VWN6|TASO2_HUMAN,tr|A0A2R8YH03|A0A2R8YH03_HUMAN" 2 1502.6638 3.8 49012 15185 2 1502.664306 752.3392 Protein TASOR 2 OS=Homo sapiens OX=9606 GN=TASOR2 PE=1 SV=1 5.84 2749.5 - 553590 - - - 0.3693 - 2.399 0.668 - 601.5 1 2 0 0.0006 14 0 0 0 5.94E+06 1.56E+06 - - - 6.1706 1 221125_WJC_METTL3_EV_vs_WT_F04.15189.15189.3 3.57E-09 17/60 K.ILDSVGIEADDDRLNK.V sp|P05387|RLA2_HUMAN 1 1771.8952 1.27 49014 15189 3 1771.893729 591.639 60S acidic ribosomal protein P2 OS=Homo sapiens OX=9606 GN=RPLP2 PE=1 SV=1 4.04 2750 - 5.69E+06 - - - -0.8347 - 3.126 0.633 - 263.1 1 2 1 -0.0015 16 0 0 0 4.31E+09 3.40E+09 - - - 8.5214 1 221125_WJC_METTL3_EV_vs_WT_F04.15190.15190.3 6.53E-05 15/48 K.VLHMSLNPTSVAR.Q sp|Q9Y6D9|MD1L1_HUMAN 1 1423.7606 1.58 49015 15190 3 1423.760301 475.5941 Mitotic spindle assembly checkpoint protein MAD1 OS=Homo sapiens OX=9606 GN=MAD1L1 PE=1 SV=2 9.73 2750.1 - 2.97E+06 - - - -0.1882 - 2.833 0.418 - 435.6 1 2 0 -0.0003 13 0 0 0 4.86E+07 3.07E+07 - - - 6.0236 1 221125_WJC_METTL3_EV_vs_WT_F04.15193.15193.3 1.68E-05 Dec-40 R.LDFTVEHDSLK.L "sp|Q15155|NOMO1_HUMAN,sp|Q5JPE7|NOMO2_HUMAN,sp|P69849|NOMO3_HUMAN,tr|A0A7I2V686|A0A7I2V686_HUMAN,tr|A0A7I2V3P4|A0A7I2V3P4_HUMAN,tr|A0A7I2V6B0|A0A7I2V6B0_HUMAN,tr|A0A7I2V4D7|A0A7I2V4D7_HUMAN,tr|A0A7I2V4T6|A0A7I2V4T6_HUMAN,tr|A0A0G2JP90|A0A0G2JP90_HUMAN,tr|A0A087X117|A0A087X117_HUMAN,tr|A0A0G2JN29|A0A0G2JN29_HUMAN,tr|A0A7I2V2Z5|A0A7I2V2Z5_HUMAN,tr|A0A087WW46|A0A087WW46_HUMAN,tr|J3KN36|J3KN36_HUMAN" 14 1302.6456 1.75 49018 15193 3 1302.645541 435.2225 Nodal modulator 1 OS=Homo sapiens OX=9606 GN=NOMO1 PE=1 SV=5 4.54 2750.3 - 1.49E+06 - - - -0.0315 - 2.187 0.508 - 224.3 1 2 0 0 11 0 0 0 1.70E+07 9.77E+06 - - - 6.4267 0.9989 221125_WJC_METTL3_EV_vs_WT_F04.15194.15194.3 0.126 Dec-44 R.NVHGINFVSPVR[166.11].N "sp|P53634|CATC_HUMAN,tr|A0A7I2V5C5|A0A7I2V5C5_HUMAN,tr|A0A7I2YQT5|A0A7I2YQT5_HUMAN,tr|A0A7I2V2Q8|A0A7I2V2Q8_HUMAN,tr|A0A7I2V466|A0A7I2V466_HUMAN,tr|A0A7I2V6E3|A0A7I2V6E3_HUMAN,tr|H0YCY8|H0YCY8_HUMAN" 7 1347.7287 1.95 49019 15194 3 1347.724363 450.2502 Dipeptidyl peptidase 1 OS=Homo sapiens OX=9606 GN=CTSC PE=1 SV=2 9.76 2750.5 - 1.11E+06 - - - -3.2091 - 2.408 0.303 - 179.3 1 2 0 -0.0043 12 0 0 0 6.78E+07 3.47E+07 - - - 4.3528 1 221125_WJC_METTL3_EV_vs_WT_F04.15195.15195.2 2.01E-09 16/28 K.FSNQETC[160.03]VEIGESVR[166.11].G "sp|P60891|PRPS1_HUMAN,tr|A0A2R8Y7H4|A0A2R8Y7H4_HUMAN,tr|A0A6Q8PHK9|A0A6Q8PHK9_HUMAN,tr|B1ALA9|B1ALA9_HUMAN,tr|B1ALA7|B1ALA7_HUMAN" 5 1763.8024 0.68 49020 15195 2 1763.800145 882.9085 Ribose-phosphate pyrophosphokinase 1 OS=Homo sapiens OX=9606 GN=PRPS1 PE=1 SV=2 4.25 2750.6 - 1.10E+06 - - - -1.2694 - 3.055 0.651 - 1024.8 1 2 0 -0.0022 15 0 0 0 1.39E+07 2.03E+07 - - - 6.5942 0.9997 221125_WJC_METTL3_EV_vs_WT_F04.15196.15196.3 0.0011 13/40 R.AVFPSIVGR[166.11]PR[166.11].Q "sp|Q6S8J3|POTEE_HUMAN,sp|P63261|ACTG_HUMAN,sp|P68133|ACTS_HUMAN,sp|P62736|ACTA_HUMAN,sp|Q9BYX7|ACTBM_HUMAN,sp|P68032|ACTC_HUMAN,sp|P60709|ACTB_HUMAN,sp|P63267|ACTH_HUMAN,sp|A5A3E0|POTEF_HUMAN,sp|P0CG38|POTEI_HUMAN,tr|A0A804GS07|A0A804GS07_HUMAN,tr|I3L3I0|I3L3I0_HUMAN,tr|G5E9R0|G5E9R0_HUMAN,tr|E7EVS6|E7EVS6_HUMAN,tr|B8ZZJ2|B8ZZJ2_HUMAN,tr|J3KT65|J3KT65_HUMAN,tr|I3L3R2|I3L3R2_HUMAN,tr|K7EM38|K7EM38_HUMAN,tr|F6QUT6|F6QUT6_HUMAN,tr|C9JTX5|C9JTX5_HUMAN,tr|A0A6Q8PH58|A0A6Q8PH58_HUMAN,tr|F6UVQ4|F6UVQ4_HUMAN,tr|F8WB63|F8WB63_HUMAN,tr|I3L1U9|I3L1U9_HUMAN,tr|A0A2R8Y793|A0A2R8Y793_HUMAN,tr|I3L4N8|I3L4N8_HUMAN,tr|C9JUM1|C9JUM1_HUMAN,tr|F8WCH0|F8WCH0_HUMAN,tr|C9JZR7|C9JZR7_HUMAN,tr|C9JFL5|C9JFL5_HUMAN,tr|A0A2R8YGF8|A0A2R8YGF8_HUMAN,tr|A6NL76|A6NL76_HUMAN" 32 1217.7148 0.96 49021 15196 3 1217.710997 406.9122 POTE ankyrin domain family member E OS=Homo sapiens OX=9606 GN=POTEE PE=2 SV=3 12 2750.7 - 830099 - - - -3.0951 - 2.469 0.398 - 247.1 1 2 0 -0.0038 11 0 0 0 7.06E+07 7.37E+07 - - - 5.5438 0.9994 221125_WJC_METTL3_EV_vs_WT_F04.15197.15197.3 0.00363 Nov-40 R.LDFTVEHDSLK[136.11].L "sp|Q15155|NOMO1_HUMAN,sp|Q5JPE7|NOMO2_HUMAN,sp|P69849|NOMO3_HUMAN,tr|A0A7I2V686|A0A7I2V686_HUMAN,tr|A0A7I2V3P4|A0A7I2V3P4_HUMAN,tr|A0A7I2V6B0|A0A7I2V6B0_HUMAN,tr|A0A7I2V4D7|A0A7I2V4D7_HUMAN,tr|A0A7I2V4T6|A0A7I2V4T6_HUMAN,tr|A0A0G2JP90|A0A0G2JP90_HUMAN,tr|A0A087X117|A0A087X117_HUMAN,tr|A0A0G2JN29|A0A0G2JN29_HUMAN,tr|A0A7I2V2Z5|A0A7I2V2Z5_HUMAN,tr|A0A087WW46|A0A087WW46_HUMAN,tr|J3KN36|J3KN36_HUMAN" 14 1310.6598 1.76 49022 15197 3 1310.655032 437.8939 Nodal modulator 1 OS=Homo sapiens OX=9606 GN=NOMO1 PE=1 SV=5 4.54 2750.9 - 806294 - - - -3.6241 - 2.208 0.389 - 150.1 1 2 0 -0.0047 11 0 0 0 1.73E+07 9.87E+06 - - - 5.1258 0.9998 221125_WJC_METTL3_EV_vs_WT_F04.15198.15198.3 0.0183 Oct-56 K.FSNQETC[160.03]VEIGESVR[166.11].G "sp|P60891|PRPS1_HUMAN,tr|A0A2R8Y7H4|A0A2R8Y7H4_HUMAN,tr|A0A6Q8PHK9|A0A6Q8PHK9_HUMAN,tr|B1ALA9|B1ALA9_HUMAN,tr|B1ALA7|B1ALA7_HUMAN" 5 1763.8024 0.82 49023 15198 3 1763.801425 588.9414 Ribose-phosphate pyrophosphokinase 1 OS=Homo sapiens OX=9606 GN=PRPS1 PE=1 SV=2 4.25 2751 - 482694 - - - -0.5437 - 1.788 0.393 - 43.5 1 2 0 -0.001 15 0 0 0 5.56E+06 6.76E+06 - - - 4.4376 0.8913 221125_WJC_METTL3_EV_vs_WT_F04.15203.15203.2 0.474 14-Sep G.LVLDHGAR[166.11].H "sp|Q92526|TCPW_HUMAN,sp|P40227|TCPZ_HUMAN,tr|J3KRI6|J3KRI6_HUMAN" 3 889.5009 0 49026 15203 2 889.500524 445.7577 T-complex protein 1 subunit zeta-2 OS=Homo sapiens OX=9606 GN=CCT6B PE=1 SV=5 6.74 2751.5 - 6.40E+06 - - - -0.4452 - 1.701 0.156 - 140.7 1 1 0 -0.0004 8 0 0 0 6.55E+04 1.25E+08 - - - 1.7952 1 221125_WJC_METTL3_EV_vs_WT_F04.15204.15204.2 1.44E-07 20-Dec R.TNAENEFVTIK.K sp|P04264|K2C1_HUMAN 1 1264.6299 131.09 49027 15204 2 1264.628878 633.3222 "Keratin, type II cytoskeletal 1 OS=Homo sapiens OX=9606 GN=KRT1 PE=1 SV=6" 4.53 2751.5 - 3.09E+06 - - - -0.8334 - 2.655 0.556 - 653.1 1 2 0 -0.0011 11 0 0 0 2.77E+08 2.11E+06 - - - 5.7888 0.9982 221125_WJC_METTL3_EV_vs_WT_F04.15205.15205.3 0.00287 13/56 R.FAVALDSEQNNIHVK[136.11].D sp|O00267|SPT5H_HUMAN 1 1691.8722 1 49028 15205 3 1691.868776 564.9647 Transcription elongation factor SPT5 OS=Homo sapiens OX=9606 GN=SUPT5H PE=1 SV=1 5.32 2751.7 - 1.70E+06 - - - -2.0439 - 1.539 0.328 - 59.2 1 2 0 -0.0035 15 0 0 0 2.53E+07 2.54E+07 - - - 3.3209 0.9993 221125_WJC_METTL3_EV_vs_WT_F04.15207.15207.3 2.62E-05 13/40 K.AVIFC[160.03]LSADK[136.11]K[136.11].C "sp|P60981|DEST_HUMAN,tr|F6RFD5|F6RFD5_HUMAN" 2 1266.6977 1.97 49030 15207 3 1266.69147 423.2398 Destrin OS=Homo sapiens OX=9606 GN=DSTN PE=1 SV=3 8.24 2751.9 - 1.25E+06 - - - -4.9136 - 2.388 0.441 - 227.1 1 2 0 -0.0062 11 0 0 0 3.91E+07 1.98E+07 - - - 5.9278 0.9999 221125_WJC_METTL3_EV_vs_WT_F04.15208.15208.3 0.000279 Dec-40 K.AVIFC[160.03]LSADKK.C "sp|P60981|DEST_HUMAN,tr|F6RFD5|F6RFD5_HUMAN" 2 1250.6693 1.97 49031 15208 3 1250.666459 417.897 Destrin OS=Homo sapiens OX=9606 GN=DSTN PE=1 SV=3 8.24 2751.9 - 1.20E+06 - - - -2.2668 - 2.044 0.449 - 182.5 1 2 0 -0.0028 11 0 0 0 3.90E+07 1.98E+07 - - - 5.5761 0.9999 221125_WJC_METTL3_EV_vs_WT_F04.15209.15209.3 0.0012 15/40 R.AVFPSIVGRPR.Q "sp|Q6S8J3|POTEE_HUMAN,sp|P63261|ACTG_HUMAN,sp|P68133|ACTS_HUMAN,sp|P62736|ACTA_HUMAN,sp|Q9BYX7|ACTBM_HUMAN,sp|P68032|ACTC_HUMAN,sp|P60709|ACTB_HUMAN,sp|P63267|ACTH_HUMAN,sp|A5A3E0|POTEF_HUMAN,sp|P0CG38|POTEI_HUMAN,tr|A0A804GS07|A0A804GS07_HUMAN,tr|I3L3I0|I3L3I0_HUMAN,tr|G5E9R0|G5E9R0_HUMAN,tr|E7EVS6|E7EVS6_HUMAN,tr|B8ZZJ2|B8ZZJ2_HUMAN,tr|J3KT65|J3KT65_HUMAN,tr|I3L3R2|I3L3R2_HUMAN,tr|K7EM38|K7EM38_HUMAN,tr|F6QUT6|F6QUT6_HUMAN,tr|C9JTX5|C9JTX5_HUMAN,tr|A0A6Q8PH58|A0A6Q8PH58_HUMAN,tr|F6UVQ4|F6UVQ4_HUMAN,tr|F8WB63|F8WB63_HUMAN,tr|I3L1U9|I3L1U9_HUMAN,tr|A0A2R8Y793|A0A2R8Y793_HUMAN,tr|I3L4N8|I3L4N8_HUMAN,tr|C9JUM1|C9JUM1_HUMAN,tr|F8WCH0|F8WCH0_HUMAN,tr|C9JZR7|C9JZR7_HUMAN,tr|C9JFL5|C9JFL5_HUMAN,tr|A0A2R8YGF8|A0A2R8YGF8_HUMAN,tr|A6NL76|A6NL76_HUMAN" 32 1197.6982 0.95 49032 15209 3 1197.697887 400.24 POTE ankyrin domain family member E OS=Homo sapiens OX=9606 GN=POTEE PE=2 SV=3 12 2752.1 - 1.14E+06 - - - -0.283 - 2.384 0.416 - 369 1 2 0 -0.0003 11 0 0 0 7.08E+07 7.42E+07 - - - 5.6459 1 221125_WJC_METTL3_EV_vs_WT_F04.15210.15210.2 7.99E-07 18/30 K.ILDSVGIEADDDR[166.11]LNK[136.11].V sp|P05387|RLA2_HUMAN 1 1789.9177 1.25 49033 15210 2 1789.909417 895.9661 60S acidic ribosomal protein P2 OS=Homo sapiens OX=9606 GN=RPLP2 PE=1 SV=1 4.04 2752.2 - 977035 - - - -4.6153 - 3.603 0.611 - 994.4 1 2 1 -0.0083 16 0 0 0 2.75E+08 2.19E+08 - - - 6.7025 1 221125_WJC_METTL3_EV_vs_WT_F04.15212.15212.2 1.45E-05 13/24 K.LYGNDFSQTTISR[166.11].F "sp|P14859|PO2F1_HUMAN,sp|P09086|PO2F2_HUMAN,sp|Q9UKI9|PO2F3_HUMAN,tr|U3KQ96|U3KQ96_HUMAN,tr|U3KQN1|U3KQN1_HUMAN,tr|H0YKT2|H0YKT2_HUMAN,tr|H0YNW1|H0YNW1_HUMAN,tr|B5ME60|B5ME60_HUMAN,tr|H0YLC5|H0YLC5_HUMAN,tr|A0A0C4DG88|A0A0C4DG88_HUMAN,tr|A0A0A0MT46|A0A0A0MT46_HUMAN,tr|H0YLL6|H0YLL6_HUMAN" 12 1510.7291 1.89 49035 15212 2 1510.73285 756.3718 "POU domain, class 2, transcription factor 1 OS=Homo sapiens OX=9606 GN=POU2F1 PE=1 SV=2" 5.84 2752.5 - 710493 - - - 2.4544 - 2.747 0.604 - 524.9 1 2 0 0.0037 13 0 0 0 4.05E+07 2.15E+07 - - - 6.0945 0.9302 221125_WJC_METTL3_EV_vs_WT_F04.15213.15213.2 0.000515 30-Nov G.SGGLGGAC[160.03]GGAGFGSR.S "sp|P48668|K2C6C_HUMAN,sp|P04259|K2C6B_HUMAN,sp|P02538|K2C6A_HUMAN" 3 1366.6048 2.05 49036 15213 2 1366.604377 684.3097 "Keratin, type II cytoskeletal 6C OS=Homo sapiens OX=9606 GN=KRT6C PE=1 SV=3" 7.96 2752.6 - 613297 - - - -0.3073 - 1.844 0.221 - 202.7 1 1 0 -0.0004 16 0 0 0 6.73E+06 3.29E+06 - - - 2.1776 1 221125_WJC_METTL3_EV_vs_WT_F04.15217.15217.2 3.81E-07 16/30 K.ILDSVGIEADDDRLNK.V sp|P05387|RLA2_HUMAN 1 1771.8952 1.25 49038 15217 2 1771.892344 886.9549 60S acidic ribosomal protein P2 OS=Homo sapiens OX=9606 GN=RPLP2 PE=1 SV=1 4.04 2753.1 - 3.86E+06 - - - -1.6163 - 3.414 0.617 - 676 1 2 1 -0.0029 16 0 0 0 2.75E+08 2.19E+08 - - - 6.6161 1 221125_WJC_METTL3_EV_vs_WT_F04.15219.15219.2 2.59E-09 14/24 K.LYGNDFSQTTISR.F "sp|P14859|PO2F1_HUMAN,sp|P09086|PO2F2_HUMAN,sp|Q9UKI9|PO2F3_HUMAN,tr|U3KQ96|U3KQ96_HUMAN,tr|U3KQN1|U3KQN1_HUMAN,tr|H0YKT2|H0YKT2_HUMAN,tr|H0YNW1|H0YNW1_HUMAN,tr|B5ME60|B5ME60_HUMAN,tr|H0YLC5|H0YLC5_HUMAN,tr|A0A0C4DG88|A0A0C4DG88_HUMAN,tr|A0A0A0MT46|A0A0A0MT46_HUMAN,tr|H0YLL6|H0YLL6_HUMAN" 12 1500.7209 1.89 49040 15219 2 1500.716836 751.3677 "POU domain, class 2, transcription factor 1 OS=Homo sapiens OX=9606 GN=POU2F1 PE=1 SV=2" 5.84 2753.3 - 2.07E+06 - - - -2.6894 - 2.637 0.651 - 581.5 1 2 0 -0.004 13 0 0 0 4.05E+07 2.15E+07 - - - 6.3366 0.9942 221125_WJC_METTL3_EV_vs_WT_F04.15220.15220.3 0.00028 15/48 K.TVELPLNK[136.11]EEIER[166.11].L sp|Q9BVJ6|UT14A_HUMAN 1 1586.8635 2.59 49041 15220 3 1586.856236 529.9618 U3 small nucleolar RNA-associated protein 14 homolog A OS=Homo sapiens OX=9606 GN=UTP14A PE=1 SV=1 4.49 2753.4 - 1.29E+06 - - - -4.5505 - 2.654 0.352 - 241 1 2 1 -0.0072 13 0 0 0 6.36E+07 2.45E+07 - - - 5.1089 0.9998 221125_WJC_METTL3_EV_vs_WT_F04.15222.15222.3 0.0879 13/36 R.RVLDELTLTK.A "sp|P13645|K1C10_HUMAN,tr|A0A1B0GVI3|A0A1B0GVI3_HUMAN" 2 1186.6921 999 49043 15222 3 1186.687967 396.5713 "Keratin, type I cytoskeletal 10 OS=Homo sapiens OX=9606 GN=KRT10 PE=1 SV=6" 6.07 2753.7 - 1.08E+06 - - - -3.5148 - 2.337 0.463 - 282.3 1 2 0 -0.0042 10 0 0 0 6.05E+07 0.00E+00 - - - 6.1799 0.9999 221125_WJC_METTL3_EV_vs_WT_F04.15231.15231.3 0.000584 Dec-44 R.IHFIEAQDLQGK.D "sp|A0FGR8|ESYT2_HUMAN,tr|A0A499FIX8|A0A499FIX8_HUMAN,tr|H7BXI1|H7BXI1_HUMAN,tr|A0A087WXU3|A0A087WXU3_HUMAN" 4 1397.7303 0.64 49050 15231 3 1397.731808 466.9174 Extended synaptotagmin-2 OS=Homo sapiens OX=9606 GN=ESYT2 PE=1 SV=1 5.32 2754.8 - 570690 - - - 1.0689 - 2.127 0.418 - 194.7 1 2 0 0.0015 12 0 0 0 1.31E+07 2.05E+07 - - - 5.2918 1 221125_WJC_METTL3_EV_vs_WT_F04.15234.15234.3 1.51E-05 Dec-44 R.INGIFPGTPLK[136.11]K[136.11].D sp|Q86XN7|PRSR1_HUMAN 1 1299.7886 1.48 49051 15234 3 1299.788168 434.2701 Proline and serine-rich protein 1 OS=Homo sapiens OX=9606 GN=PROSER1 PE=1 SV=2 10 2755.2 - 1.75E+06 - - - -0.3 - 2.412 0.468 - 188.3 1 2 0 -0.0004 12 0 0 0 5.62E+07 3.79E+07 - - - 6.1981 0.9999 221125_WJC_METTL3_EV_vs_WT_F04.15237.15237.3 4.55E-05 19/56 K.LQELPDAVPHGEMPR[166.11].H "sp|P33992|MCM5_HUMAN,tr|B1AHB1|B1AHB1_HUMAN,tr|B1AHB2|B1AHB2_HUMAN" 3 1697.8435 0.74 49053 15237 3 1697.843929 566.9551 DNA replication licensing factor MCM5 OS=Homo sapiens OX=9606 GN=MCM5 PE=1 SV=5 4.65 2755.5 - 1.95E+06 - - - 0.2762 - 2.187 0.47 - 378.2 1 2 0 0.0005 15 0 0 0 2.99E+07 4.02E+07 - - - 5.8218 1 221125_WJC_METTL3_EV_vs_WT_F04.15239.15239.2 8.85E-08 16/28 L.LDSVGIEADDDR[166.11]LNK[136.11].V sp|P05387|RLA2_HUMAN 1 1676.8336 1.44 49055 15239 2 1676.830926 839.4241 60S acidic ribosomal protein P2 OS=Homo sapiens OX=9606 GN=RPLP2 PE=1 SV=1 4.04 2755.7 - 762288 - - - -1.603 - 3.016 0.594 - 807 1 1 1 -0.0027 15 0 0 0 2.09E+07 1.45E+07 - - - 6.1415 0.9999 221125_WJC_METTL3_EV_vs_WT_F04.15241.15241.3 7.01E-05 14/60 K.GDITPLMAAANGGHVK.L "sp|O75179|ANR17_HUMAN,tr|H0YM23|H0YM23_HUMAN,tr|A0A1W2PQ15|A0A1W2PQ15_HUMAN" 3 1550.7875 1.7 49057 15241 3 1550.786641 517.9364 Ankyrin repeat domain-containing protein 17 OS=Homo sapiens OX=9606 GN=ANKRD17 PE=1 SV=3 6.74 2756 - 677810 - - - -0.5617 - 2.484 0.385 - 170.6 1 2 0 -0.0009 16 0 0 0 1.46E+07 8.61E+06 - - - 5.1667 0.9964 221125_WJC_METTL3_EV_vs_WT_F04.15244.15244.3 0.237 Aug-44 K.VLSLNFSEC[160.03]HTK.L "sp|Q9UN86|G3BP2_HUMAN,tr|A0A7I2V3E2|A0A7I2V3E2_HUMAN,tr|D6RAC7|D6RAC7_HUMAN,tr|D6RB17|D6RB17_HUMAN,tr|A0A7I2YQS2|A0A7I2YQS2_HUMAN,tr|A0A7I2YQG8|A0A7I2YQG8_HUMAN,tr|A0A7I2V572|A0A7I2V572_HUMAN,tr|D6RBR0|D6RBR0_HUMAN,tr|D6RBW8|D6RBW8_HUMAN" 9 1433.6973 1.29 49058 15244 3 1433.694828 478.9064 Ras GTPase-activating protein-binding protein 2 OS=Homo sapiens OX=9606 GN=G3BP2 PE=1 SV=2 6.71 2756.4 - 9.18E+06 - - - -1.7242 - 1.538 0.266 - 79.9 1 2 0 -0.0025 12 0 0 0 1.48E+08 1.15E+08 - - - 2.6982 1 221125_WJC_METTL3_EV_vs_WT_F04.15246.15246.3 1.84E-06 17/56 K.LQELPDAVPHGEMPR.H "sp|P33992|MCM5_HUMAN,tr|B1AHB1|B1AHB1_HUMAN,tr|B1AHB2|B1AHB2_HUMAN" 3 1687.8352 0.75 49060 15246 3 1687.836644 563.619 DNA replication licensing factor MCM5 OS=Homo sapiens OX=9606 GN=MCM5 PE=1 SV=5 4.65 2756.6 - 1.32E+06 - - - 0.8615 - 3.094 0.453 - 342.5 1 2 0 0.0015 15 0 0 0 3.01E+07 4.02E+07 - - - 6.5373 1 221125_WJC_METTL3_EV_vs_WT_F04.15247.15247.2 8.63E-09 18/28 L.LDSVGIEADDDRLNK.V sp|P05387|RLA2_HUMAN 1 1658.8111 1.44 49061 15247 2 1658.812289 830.4128 60S acidic ribosomal protein P2 OS=Homo sapiens OX=9606 GN=RPLP2 PE=1 SV=1 4.04 2756.7 - 1.15E+06 - - - 0.6903 - 3.313 0.589 - 849.2 1 1 1 0.0011 15 0 0 0 2.09E+07 1.45E+07 - - - 6.336 1 221125_WJC_METTL3_EV_vs_WT_F04.15251.15251.2 1.73E-10 19/26 L.DSVGIEADDDR[166.11]LNK[136.11].V sp|P05387|RLA2_HUMAN 1 1563.7495 2.02 49063 15251 2 1563.744569 782.8821 60S acidic ribosomal protein P2 OS=Homo sapiens OX=9606 GN=RPLP2 PE=1 SV=1 4.04 2757.3 - 1.77E+06 - - - -3.1853 - 3.359 0.673 - 1404.9 1 1 1 -0.005 14 0 0 0 4.16E+07 2.06E+07 - - - 7.0508 0.9907 221125_WJC_METTL3_EV_vs_WT_F04.15253.15253.2 0.539 12-Aug K.FASFIDK.V "sp|Q86Y46|K2C73_HUMAN,sp|Q7RTS7|K2C74_HUMAN,sp|Q9NSB2|KRT84_HUMAN,sp|P48668|K2C6C_HUMAN,sp|Q3SY84|K2C71_HUMAN,sp|P05787|K2C8_HUMAN,sp|Q01546|K22O_HUMAN,sp|P19013|K2C4_HUMAN,sp|Q7Z794|K2C1B_HUMAN,sp|Q8N1N4|K2C78_HUMAN,sp|P12035|K2C3_HUMAN,sp|P04264|K2C1_HUMAN,sp|P04259|K2C6B_HUMAN,sp|P13647|K2C5_HUMAN,sp|P35908|K22E_HUMAN,sp|Q14CN4|K2C72_HUMAN,sp|P08729|K2C7_HUMAN,sp|O95678|K2C75_HUMAN,sp|Q5XKE5|K2C79_HUMAN,sp|P02538|K2C6A_HUMAN,tr|F8VUG2|F8VUG2_HUMAN,tr|F8W0C6|F8W0C6_HUMAN,tr|F8W1U3|F8W1U3_HUMAN,tr|H0YHD9|H0YHD9_HUMAN,tr|F8W1S1|F8W1S1_HUMAN,tr|F8VS61|F8VS61_HUMAN" 26 826.4225 2.09 49065 15253 2 826.420416 414.2185 "Keratin, type II cytoskeletal 73 OS=Homo sapiens OX=9606 GN=KRT73 PE=1 SV=1" 5.84 2757.5 - 1.95E+06 - - - -2.5278 - 1.628 0.122 - 174.3 1 2 0 -0.0021 7 0 0 0 2.60E+07 1.24E+07 - - - 1.4856 0.9998 221125_WJC_METTL3_EV_vs_WT_F04.15254.15254.3 7.51E-07 16/40 R.LKVGLQVVAVK.A "sp|P10809|CH60_HUMAN,tr|A0A7I2V2X6|A0A7I2V2X6_HUMAN,tr|A0A7I2YQK6|A0A7I2YQK6_HUMAN,tr|A0A7I2V599|A0A7I2V599_HUMAN,tr|A0A7I2V5M1|A0A7I2V5M1_HUMAN" 5 1152.7594 1.04 49066 15254 3 1152.756715 385.2604 "60 kDa heat shock protein, mitochondrial OS=Homo sapiens OX=9606 GN=HSPD1 PE=1 SV=2" 10 2757.6 - 1.02E+06 - - - -2.3552 - 2.57 0.53 - 270.4 1 2 1 -0.0027 11 0 0 0 2.71E+07 2.61E+07 - - - 7.1297 0.9911 221125_WJC_METTL3_EV_vs_WT_F04.15255.15255.3 4.02E-10 18/72 K.PSTASAVPELATDPELEK[136.11]K[136.11].L "sp|Q86U44|MTA70_HUMAN,tr|B4E349|B4E349_HUMAN,tr|F5H6D8|F5H6D8_HUMAN,tr|H0YFV6|H0YFV6_HUMAN,tr|B4DTN4|B4DTN4_HUMAN" 5 1998.0492 0.001 49067 15255 3 1998.041097 667.0237 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 4.41 2757.8 - 934359 - - - -4.0565 - 3.625 0.582 - 343.1 1 1 0 -0.0081 19 0 0 0 0.00E+00 9.51E+06 - - - 8.1905 0.9998 221125_WJC_METTL3_EV_vs_WT_F04.15256.15256.2 1.80E-07 14/32 K.VIVVGNPANTNC[160.03]LTASK[136.11].S "sp|P40925|MDHC_HUMAN,tr|C9JRL4|C9JRL4_HUMAN,tr|C9JF79|C9JF79_HUMAN,tr|A0A5K1VW95|A0A5K1VW95_HUMAN,tr|B9A041|B9A041_HUMAN" 5 1764.9284 1.36 49068 15256 2 1764.924603 883.4715 "Malate dehydrogenase, cytoplasmic OS=Homo sapiens OX=9606 GN=MDH1 PE=1 SV=4" 8.19 2757.9 - 737083 - - - -2.1338 - 2.353 0.588 - 376.2 1 2 0 -0.0038 17 0 0 0 1.34E+07 9.83E+06 - - - 5.4865 1 221125_WJC_METTL3_EV_vs_WT_F04.15260.15260.3 0.000192 14/44 R.INGIFPGTPLKK.D sp|Q86XN7|PRSR1_HUMAN 1 1283.7602 1.48 49070 15260 3 1283.757784 428.9273 Proline and serine-rich protein 1 OS=Homo sapiens OX=9606 GN=PROSER1 PE=1 SV=2 10 2758.4 - 3.69E+06 - - - -1.8493 - 2.155 0.548 - 160.7 1 2 0 -0.0024 12 0 0 0 5.62E+07 3.79E+07 - - - 6.7772 0.9561 221125_WJC_METTL3_EV_vs_WT_F04.15263.15263.3 0.168 Sep-44 R.DGWPAMGIHGDK[136.11].S "sp|P17844|DDX5_HUMAN,tr|A0A7I2V5F5|A0A7I2V5F5_HUMAN,tr|A0A7I2V507|A0A7I2V507_HUMAN,tr|J3KTA4|J3KTA4_HUMAN,tr|A0A0G2JLI4|A0A0G2JLI4_HUMAN,tr|A0A7I2V2S0|A0A7I2V2S0_HUMAN" 6 1290.5907 1.55 49073 15263 3 1290.588145 431.2042 Probable ATP-dependent RNA helicase DDX5 OS=Homo sapiens OX=9606 GN=DDX5 PE=1 SV=1 5.21 2758.6 - 3.15E+06 - - - -1.9456 - 1.256 0.186 - 46 1 2 0 -0.0025 12 0 0 0 1.20E+08 7.70E+07 - - - 1.2448 0.9998 221125_WJC_METTL3_EV_vs_WT_F04.15265.15265.3 1.58E-05 17/40 R.LK[136.11]VGLQVVAVK[136.11].A "sp|P10809|CH60_HUMAN,tr|A0A7I2V2X6|A0A7I2V2X6_HUMAN,tr|A0A7I2YQK6|A0A7I2YQK6_HUMAN,tr|A0A7I2V599|A0A7I2V599_HUMAN,tr|A0A7I2V5M1|A0A7I2V5M1_HUMAN" 5 1168.7878 1.04 49075 15265 3 1168.784218 390.6032 "60 kDa heat shock protein, mitochondrial OS=Homo sapiens OX=9606 GN=HSPD1 PE=1 SV=2" 10 2758.9 - 1.44E+06 - - - -3.0904 - 2.895 0.563 - 340.5 1 2 1 -0.0036 11 0 0 0 2.70E+07 2.61E+07 - - - 7.8357 0.9999 221125_WJC_METTL3_EV_vs_WT_F04.15266.15266.3 0.000229 13/36 R.QWKPQLGFNR.D sp|Q9H0D6|XRN2_HUMAN 1 1272.6727 0.87 49076 15266 3 1272.67139 425.2315 5'-3' exoribonuclease 2 OS=Homo sapiens OX=9606 GN=XRN2 PE=1 SV=1 11 2759 - 1.09E+06 - - - -1.0608 - 2.417 0.4 - 292.8 1 2 0 -0.0013 10 0 0 0 2.11E+07 2.42E+07 - - - 5.5766 1 221125_WJC_METTL3_EV_vs_WT_F04.15267.15267.2 8.98E-07 16/32 K.VIVVGNPANTNC[160.03]LTASK.S "sp|P40925|MDHC_HUMAN,tr|C9JRL4|C9JRL4_HUMAN,tr|C9JF79|C9JF79_HUMAN,tr|A0A5K1VW95|A0A5K1VW95_HUMAN,tr|B9A041|B9A041_HUMAN" 5 1756.9142 1.36 49077 15267 2 1756.909954 879.4644 "Malate dehydrogenase, cytoplasmic OS=Homo sapiens OX=9606 GN=MDH1 PE=1 SV=4" 8.19 2759.1 - 427863 - - - -2.3991 - 2.653 0.619 - 646.6 1 2 0 -0.0042 17 0 0 0 1.34E+07 9.83E+06 - - - 6.0104 0.9899 221125_WJC_METTL3_EV_vs_WT_F04.15271.15271.2 0.0198 22-Sep R.EMDR[166.11]ETLIDVAR[166.11].T sp|P40227|TCPZ_HUMAN 1 1466.7302 0.38 49079 15271 2 1466.727743 734.3724 T-complex protein 1 subunit zeta OS=Homo sapiens OX=9606 GN=CCT6A PE=1 SV=3 4.32 2759.7 - 5.29E+06 - - - -1.6874 - 1.532 0.382 - 144.7 1 2 1 -0.0025 12 0 0 0 3.10E+07 8.17E+07 - - - 2.9841 0.9999 221125_WJC_METTL3_EV_vs_WT_F04.15272.15272.3 8.09E-06 Nov-44 R.NVHGINFVSPVR.N "sp|P53634|CATC_HUMAN,tr|A0A7I2V5C5|A0A7I2V5C5_HUMAN,tr|A0A7I2YQT5|A0A7I2YQT5_HUMAN,tr|A0A7I2V2Q8|A0A7I2V2Q8_HUMAN,tr|A0A7I2V466|A0A7I2V466_HUMAN,tr|A0A7I2V6E3|A0A7I2V6E3_HUMAN,tr|H0YCY8|H0YCY8_HUMAN" 7 1337.7204 1.95 49080 15272 3 1337.71695 446.9141 Dipeptidyl peptidase 1 OS=Homo sapiens OX=9606 GN=CTSC PE=1 SV=2 9.76 2759.7 - 2.83E+06 - - - -2.5925 - 2.059 0.506 - 135.8 1 2 0 -0.0035 12 0 0 0 6.78E+07 3.47E+07 - - - 6.1823 0.9891 221125_WJC_METTL3_EV_vs_WT_F04.15273.15273.2 3.42E-05 15/38 S.GLYQGAGGPGPGGFGAQGPK[136.11].G "sp|P0DMV8|HS71A_HUMAN,sp|P0DMV9|HS71B_HUMAN,tr|V9GZ37|V9GZ37_HUMAN,tr|A0A0G2JIW1|A0A0G2JIW1_HUMAN" 4 1779.8784 0.001 49081 15273 2 1779.878338 890.9465 Heat shock 70 kDa protein 1A OS=Homo sapiens OX=9606 GN=HSPA1A PE=1 SV=1 8.59 2759.8 - 2.44E+06 - - - -0.0247 - 1.832 0.497 - 216.2 1 1 0 0 20 0 0 0 0.00E+00 4.56E+07 - - - 4.2003 0.9998 221125_WJC_METTL3_EV_vs_WT_F04.15274.15274.3 2.13E-05 17/48 K.TVELPLNKEEIER.L sp|Q9BVJ6|UT14A_HUMAN 1 1568.841 2.64 49082 15274 3 1568.839308 523.9543 U3 small nucleolar RNA-associated protein 14 homolog A OS=Homo sapiens OX=9606 GN=UTP14A PE=1 SV=1 4.49 2759.8 - 2.27E+06 - - - -1.0702 - 2.69 0.454 - 366 1 2 1 -0.0017 13 0 0 0 6.48E+07 2.45E+07 - - - 6.2841 0.9301 221125_WJC_METTL3_EV_vs_WT_F04.15275.15275.2 0.00896 22-Oct K.VLSLNFSEC[160.03]HTK.L "sp|Q9UN86|G3BP2_HUMAN,tr|A0A7I2V3E2|A0A7I2V3E2_HUMAN,tr|D6RAC7|D6RAC7_HUMAN,tr|D6RB17|D6RB17_HUMAN,tr|A0A7I2YQS2|A0A7I2YQS2_HUMAN,tr|A0A7I2YQG8|A0A7I2YQG8_HUMAN,tr|A0A7I2V572|A0A7I2V572_HUMAN,tr|D6RBR0|D6RBR0_HUMAN,tr|D6RBW8|D6RBW8_HUMAN" 9 1433.6973 -1 49083 15275 2 1433.685603 717.8559 Ras GTPase-activating protein-binding protein 2 OS=Homo sapiens OX=9606 GN=G3BP2 PE=1 SV=2 6.71 2759.9 - 2.08E+06 - - - -8.1586 - 1.59 0.363 - 266.1 1 2 0 -0.0117 12 0 0 0 0.00E+00 0.00E+00 - - - 2.9386 1 221125_WJC_METTL3_EV_vs_WT_F04.15276.15276.3 1.26E-07 16/48 K.VSHIDVITAEMAK[136.11].D sp|Q9UQE7|SMC3_HUMAN 1 1420.7476 0.4 49084 15276 3 1420.747722 474.5898 Structural maintenance of chromosomes protein 3 OS=Homo sapiens OX=9606 GN=SMC3 PE=1 SV=2 5.32 2760 - 1.07E+06 - - - 0.1204 - 2.924 0.448 - 511 1 2 0 0.0002 13 0 0 0 2.36E+07 5.93E+07 - - - 6.4438 0.9999 221125_WJC_METTL3_EV_vs_WT_F04.15277.15277.2 6.49E-06 22-Dec K.SQVDAQLLTVQK[136.11].L "sp|O75150|BRE1B_HUMAN,tr|H3BP71|H3BP71_HUMAN,tr|A0A087WTK2|A0A087WTK2_HUMAN" 3 1336.7442 0.81 49085 15277 2 1336.745158 669.3794 E3 ubiquitin-protein ligase BRE1B OS=Homo sapiens OX=9606 GN=RNF40 PE=1 SV=5 5.55 2760.2 - 974301 - - - 0.7316 - 2.429 0.52 - 371.4 1 2 0 0.001 12 0 0 0 8.37E+06 1.03E+07 - - - 5.2165 1 221125_WJC_METTL3_EV_vs_WT_F04.15278.15278.3 5.69E-07 23/60 R.GQAAVQQLQAEGLSPR.F "sp|P16152|CBR1_HUMAN,sp|O75828|CBR3_HUMAN,tr|E9PQ63|E9PQ63_HUMAN,tr|A8MTM1|A8MTM1_HUMAN" 4 1651.8642 1.6 49086 15278 3 1651.860161 551.6287 Carbonyl reductase [NADPH] 1 OS=Homo sapiens OX=9606 GN=CBR1 PE=1 SV=3 6 2760.3 - 705571 - - - -2.4342 - 3.699 0.534 - 758 1 2 0 -0.004 16 0 0 0 1.47E+07 9.18E+06 - - - 7.8488 0.9982 221125_WJC_METTL3_EV_vs_WT_F04.15284.15284.3 0.152 13/32 K.TR[166.11]TELFDLK[136.11].T "sp|Q13948|CASP_HUMAN,sp|P39880|CUX1_HUMAN,tr|A0A2R8Y8D0|A0A2R8Y8D0_HUMAN,tr|A0A2R8Y852|A0A2R8Y852_HUMAN,tr|A0A2R8YDI1|A0A2R8YDI1_HUMAN" 5 1139.6305 0.001 49090 15284 3 1139.628794 380.8841 Protein CASP OS=Homo sapiens OX=9606 GN=CUX1 PE=1 SV=2 5.74 2761 - 3.17E+06 - - - -1.5356 - 2.32 0.283 - 319.8 1 2 1 -0.0018 9 0 0 0 0.00E+00 2.52E+07 - - - 4.231 0.9999 221125_WJC_METTL3_EV_vs_WT_F04.15285.15285.3 5.39E-07 20/56 R.LEAFGQGESVLKEPK.Y "sp|Q9BUK6|MSTO1_HUMAN,tr|A0A3B3IUD2|A0A3B3IUD2_HUMAN" 2 1630.8566 1.56 49091 15285 3 1630.855374 544.6262 Protein misato homolog 1 OS=Homo sapiens OX=9606 GN=MSTO1 PE=1 SV=1 4.79 2761.1 - 1.81E+06 - - - -0.7744 - 3.439 0.525 - 471 1 2 1 -0.0013 15 0 0 0 1.62E+07 1.04E+07 - - - 7.6159 0.9999 221125_WJC_METTL3_EV_vs_WT_F04.15286.15286.2 0.000907 13/20 R.QNQFYDTQVIK.Q "sp|Q9BUJ2|HNRL1_HUMAN,tr|M0R0K8|M0R0K8_HUMAN,tr|M0QYZ0|M0QYZ0_HUMAN,tr|A0A0A0MRA5|A0A0A0MRA5_HUMAN,tr|M0QZV6|M0QZV6_HUMAN,tr|B7Z4B8|B7Z4B8_HUMAN,tr|M0R203|M0R203_HUMAN" 7 1382.683 1.4 49092 15286 2 1382.683356 692.3488 Heterogeneous nuclear ribonucleoprotein U-like protein 1 OS=Homo sapiens OX=9606 GN=HNRNPUL1 PE=1 SV=2 5.83 2761.3 - 1.71E+06 - - - 0.2358 - 2.381 0.501 - 817.8 1 2 0 0.0003 11 0 0 0 7.37E+07 5.25E+07 - - - 5.0881 0.9993 221125_WJC_METTL3_EV_vs_WT_F04.15287.15287.2 0.000222 20-Dec R.QNQFYDTQVIK[136.11].Q "sp|Q9BUJ2|HNRL1_HUMAN,tr|M0R0K8|M0R0K8_HUMAN,tr|M0QYZ0|M0QYZ0_HUMAN,tr|A0A0A0MRA5|A0A0A0MRA5_HUMAN,tr|M0QZV6|M0QZV6_HUMAN,tr|B7Z4B8|B7Z4B8_HUMAN,tr|M0R203|M0R203_HUMAN" 7 1390.6972 1.42 49093 15287 2 1390.692549 696.3559 Heterogeneous nuclear ribonucleoprotein U-like protein 1 OS=Homo sapiens OX=9606 GN=HNRNPUL1 PE=1 SV=2 5.83 2761.4 - 1.40E+06 - - - -3.3659 - 2.36 0.485 - 688.2 1 2 0 -0.0047 11 0 0 0 7.37E+07 5.20E+07 - - - 4.9446 0.9998 221125_WJC_METTL3_EV_vs_WT_F04.15289.15289.2 8.82E-06 13/24 K.VQVSFC[160.03]APGAPGR.S "sp|Q9HCJ3|RAVR2_HUMAN,tr|E9PE10|E9PE10_HUMAN" 2 1344.6609 1.09 49095 15289 2 1344.659831 673.3377 Ribonucleoprotein PTB-binding 2 OS=Homo sapiens OX=9606 GN=RAVER2 PE=1 SV=2 8.22 2761.6 - 1.29E+06 - - - -0.7615 - 2.956 0.332 - 523.8 1 2 0 -0.001 13 0 0 0 2.25E+07 2.07E+07 - - - 4.2745 1 221125_WJC_METTL3_EV_vs_WT_F04.15290.15290.3 1.01E-07 15/48 R.FDSPESHVGVAWR[166.11].L sp|P35520|CBS_HUMAN 1 1495.7083 0.98 49096 15290 3 1495.706136 499.5767 Cystathionine beta-synthase OS=Homo sapiens OX=9606 GN=CBS PE=1 SV=2 5.32 2761.7 - 1.27E+06 - - - -1.4782 - 2.726 0.561 - 230.6 1 2 0 -0.0022 13 0 0 0 1.69E+07 1.73E+07 - - - 7.513 0.9984 221125_WJC_METTL3_EV_vs_WT_F04.15291.15291.3 5.61E-06 15/48 A.DAPEEEDHVLVLR.K "sp|P07237|PDIA1_HUMAN,tr|A0A7P0TA97|A0A7P0TA97_HUMAN,tr|A0A7P0T8C0|A0A7P0T8C0_HUMAN,tr|H7BZ94|H7BZ94_HUMAN,tr|A0A7P0Z4B2|A0A7P0Z4B2_HUMAN,tr|A0A7P0TA71|A0A7P0TA71_HUMAN,tr|I3L4M2|I3L4M2_HUMAN,tr|A0A7P0T9D6|A0A7P0T9D6_HUMAN,tr|A0A7P0T9K9|A0A7P0T9K9_HUMAN,tr|H0Y3Z3|H0Y3Z3_HUMAN,tr|A0A7P0Z4S2|A0A7P0Z4S2_HUMAN,tr|I3NI03|I3NI03_HUMAN,tr|A0A7P0TA35|A0A7P0TA35_HUMAN,tr|A0A7P0TAX9|A0A7P0TAX9_HUMAN,tr|I3L1Y5|I3L1Y5_HUMAN,tr|I3L514|I3L514_HUMAN,tr|A0A7P0Z476|A0A7P0Z476_HUMAN,tr|A0A7P0Z4F8|A0A7P0Z4F8_HUMAN,tr|A0A7P0TBP8|A0A7P0TBP8_HUMAN,tr|A0A7P0TB26|A0A7P0TB26_HUMAN,tr|A0A7P0T9U6|A0A7P0T9U6_HUMAN,tr|A0A7P0T9E3|A0A7P0T9E3_HUMAN,tr|A0A7P0TBA3|A0A7P0TBA3_HUMAN,tr|I3L0S0|I3L0S0_HUMAN,tr|I3L3P5|I3L3P5_HUMAN,tr|A0A7P0T940|A0A7P0T940_HUMAN,tr|A0A7P0T8J3|A0A7P0T8J3_HUMAN,tr|A0A7P0Z4J0|A0A7P0Z4J0_HUMAN,tr|A0A7P0T9S9|A0A7P0T9S9_HUMAN,tr|A0A7P0T8X1|A0A7P0T8X1_HUMAN,tr|I3L3U6|I3L3U6_HUMAN" 31 1520.7471 1.57 49097 15291 3 1520.748299 507.923 Protein disulfide-isomerase OS=Homo sapiens OX=9606 GN=P4HB PE=1 SV=3 4.17 2761.8 - 1.16E+06 - - - 0.797 - 2.991 0.535 - 381 1 1 0 0.0012 13 0 0 0 8.73E+07 5.55E+07 - - - 7.4749 1 221125_WJC_METTL3_EV_vs_WT_F04.15292.15292.2 4.38E-09 19/32 K.AVTAFSSTETGSAEGFK.S tr|A0A804HKC3|A0A804HKC3_HUMAN 1 1688.7893 4.8 49098 15292 2 1688.786454 845.4019 Protein PRRC2B (Fragment) OS=Homo sapiens OX=9606 GN=PRRC2B PE=4 SV=1 4.53 2761.9 - 1.04E+06 - - - -1.7125 - 3.755 0.664 - 1347.5 1 2 0 -0.0029 17 0 0 0 1.29E+07 2.68E+06 - - - 7.1973 0.999 221125_WJC_METTL3_EV_vs_WT_F04.15293.15293.3 0.0112 Nov-40 R.NWRPYC[160.03]GMLSK.S "sp|Q9Y2L1|RRP44_HUMAN,tr|F2Z2C0|F2Z2C0_HUMAN,tr|G3V1J5|G3V1J5_HUMAN" 3 1410.6537 8.91 49099 15293 3 1410.652071 471.2252 Exosome complex exonuclease RRP44 OS=Homo sapiens OX=9606 GN=DIS3 PE=1 SV=2 9.31 2762 - 1.02E+06 - - - -1.1271 - 1.872 0.275 - 128.9 1 2 0 -0.0016 11 0 0 0 1.42E+07 1.59E+06 - - - 3.3868 0.9401 221125_WJC_METTL3_EV_vs_WT_F04.15298.15298.2 0.000554 22-Oct F.SSSGIGFGESLK[136.11].A sp|P49790|NU153_HUMAN 1 1175.5914 0.82 49104 15298 2 1175.594129 588.803 Nuclear pore complex protein Nup153 OS=Homo sapiens OX=9606 GN=NUP153 PE=1 SV=2 5.72 2762.6 - 505657 - - - 2.3486 - 1.999 0.338 - 216.9 1 1 0 0.0028 12 0 0 0 3.61E+06 4.42E+06 - - - 3.3591 0.9997 221125_WJC_METTL3_EV_vs_WT_F04.15299.15299.2 0.0178 22-Sep R.DGWPAMGIHGDK.S "sp|P17844|DDX5_HUMAN,tr|A0A7I2V5F5|A0A7I2V5F5_HUMAN,tr|A0A7I2V507|A0A7I2V507_HUMAN,tr|J3KTA4|J3KTA4_HUMAN,tr|A0A0G2JLI4|A0A0G2JLI4_HUMAN,tr|A0A7I2V2S0|A0A7I2V2S0_HUMAN" 6 1282.5765 1.72 49105 15299 2 1282.574414 642.2955 Probable ATP-dependent RNA helicase DDX5 OS=Homo sapiens OX=9606 GN=DDX5 PE=1 SV=1 5.21 2762.8 - 495341 - - - -1.5921 - 1.835 0.468 - 132.1 1 2 0 -0.002 12 0 0 0 1.36E+07 7.88E+06 - - - 4.0942 0.9996 221125_WJC_METTL3_EV_vs_WT_F04.15302.15302.2 0.0247 13/22 K.YQLDPTASISAK.V "sp|P45880|VDAC2_HUMAN,tr|A0A0A0MR02|A0A0A0MR02_HUMAN" 2 1292.6612 1.59 49107 15302 2 1292.659866 647.3379 Voltage-dependent anion-selective channel protein 2 OS=Homo sapiens OX=9606 GN=VDAC2 PE=1 SV=2 5.83 2763.1 - 1.74E+06 - - - -1.0567 - 2.084 0.356 - 393.7 1 2 0 -0.0014 12 0 0 0 9.41E+07 5.91E+07 - - - 3.602 1 221125_WJC_METTL3_EV_vs_WT_F04.15304.15304.2 1.22E-06 16/30 R.VEAAQETVADYQQTIK.K "sp|Q14203|DCTN1_HUMAN,tr|A0A804CDA6|A0A804CDA6_HUMAN,tr|E7EX90|E7EX90_HUMAN,tr|A0A7P0Z4C3|A0A7P0Z4C3_HUMAN,tr|Q6AWB1|Q6AWB1_HUMAN" 5 1792.8843 1.46 49108 15304 2 1792.885354 897.4494 Dynactin subunit 1 OS=Homo sapiens OX=9606 GN=DCTN1 PE=1 SV=3 4.14 2763.3 - 2.22E+06 - - - 0.5829 - 3.686 0.52 - 901.5 1 2 0 0.001 16 0 0 0 1.19E+07 8.13E+06 - - - 6.0887 0.9999 221125_WJC_METTL3_EV_vs_WT_F04.15306.15306.2 3.13E-06 17/30 R.TAAANAAAGAAENAFR.A sp|O14828|SCAM3_HUMAN 1 1475.7117 1.19 49110 15306 2 1475.711988 738.8631 Secretory carrier-associated membrane protein 3 OS=Homo sapiens OX=9606 GN=SCAMP3 PE=1 SV=3 5.66 2763.4 - 3.92E+06 - - - 0.1924 - 2.933 0.493 - 960.1 1 2 0 0.0003 16 0 0 0 2.97E+07 2.49E+07 - - - 5.3277 0.9999 221125_WJC_METTL3_EV_vs_WT_F04.15307.15307.3 5.93E-05 Nov-48 R.NYLHYSLYDQAEK[136.11].L sp|O43242|PSMD3_HUMAN 1 1650.7769 0.65 49111 15307 3 1650.778689 551.2663 26S proteasome non-ATPase regulatory subunit 3 OS=Homo sapiens OX=9606 GN=PSMD3 PE=1 SV=2 5.32 2763.5 - 1.82E+06 - - - 1.0613 - 2.155 0.424 - 96.6 1 2 0 0.0018 13 0 0 0 6.04E+06 9.29E+06 - - - 5.3484 1 221125_WJC_METTL3_EV_vs_WT_F04.15308.15308.3 7.57E-06 Nov-48 K.VSHIDVITAEMAK.D sp|Q9UQE7|SMC3_HUMAN 1 1412.7334 0.4 49112 15308 3 1412.733681 471.9184 Structural maintenance of chromosomes protein 3 OS=Homo sapiens OX=9606 GN=SMC3 PE=1 SV=2 5.32 2763.5 - 1.82E+06 - - - 0.2336 - 2.347 0.457 - 226.7 1 2 0 0.0003 13 0 0 0 2.37E+07 5.92E+07 - - - 5.9481 1 221125_WJC_METTL3_EV_vs_WT_F04.15309.15309.3 0.000123 15/60 R.VEAAQETVADYQQTIK[136.11].K "sp|Q14203|DCTN1_HUMAN,tr|A0A804CDA6|A0A804CDA6_HUMAN,tr|E7EX90|E7EX90_HUMAN,tr|A0A7P0Z4C3|A0A7P0Z4C3_HUMAN,tr|Q6AWB1|Q6AWB1_HUMAN" 5 1800.8985 0.38 49113 15309 3 1800.899041 601.3068 Dynactin subunit 1 OS=Homo sapiens OX=9606 GN=DCTN1 PE=1 SV=3 4.14 2763.6 - 1.81E+06 - - - 0.2954 - 2.489 0.508 - 322.5 1 2 0 0.0005 16 0 0 0 4.63E+06 1.21E+07 - - - 6.5433 1 221125_WJC_METTL3_EV_vs_WT_F04.15310.15310.2 9.88E-11 15/30 R.VEAAQETVADYQQTIK[136.11].K "sp|Q14203|DCTN1_HUMAN,tr|A0A804CDA6|A0A804CDA6_HUMAN,tr|E7EX90|E7EX90_HUMAN,tr|A0A7P0Z4C3|A0A7P0Z4C3_HUMAN,tr|Q6AWB1|Q6AWB1_HUMAN" 5 1800.8985 1.46 49114 15310 2 1800.89941 901.4565 Dynactin subunit 1 OS=Homo sapiens OX=9606 GN=DCTN1 PE=1 SV=3 4.14 2763.7 - 1.22E+06 - - - 0.5003 - 3.44 0.515 - 670.1 1 2 0 0.0009 16 0 0 0 1.19E+07 8.13E+06 - - - 5.882 0.9997 221125_WJC_METTL3_EV_vs_WT_F04.15311.15311.3 0.000626 Dec-48 R.NYLHYSLYDQAEK.L sp|O43242|PSMD3_HUMAN 1 1642.7627 0.65 49115 15311 3 1642.762882 548.5949 26S proteasome non-ATPase regulatory subunit 3 OS=Homo sapiens OX=9606 GN=PSMD3 PE=1 SV=2 5.32 2763.9 - 1.05E+06 - - - 0.0883 - 1.815 0.372 - 107 1 2 0 0.0001 13 0 0 0 6.04E+06 9.29E+06 - - - 4.3036 1 221125_WJC_METTL3_EV_vs_WT_F04.15312.15312.2 1.21E-08 15/28 R.QMPLSSAGLQNSVAK.R "sp|Q8IWC1|MA7D3_HUMAN,tr|A0A0A0MRP0|A0A0A0MRP0_HUMAN" 2 1529.7872 1.42 49116 15312 2 1529.787277 765.9009 MAP7 domain-containing protein 3 OS=Homo sapiens OX=9606 GN=MAP7D3 PE=1 SV=2 8.75 2764 - 1.04E+06 - - - 0.0654 - 2.597 0.639 - 793.2 1 2 0 0.0001 15 0 0 0 8.34E+06 5.87E+06 - - - 6.107 0.9917 221125_WJC_METTL3_EV_vs_WT_F04.15313.15313.2 0.049 16-Oct K.TR[166.11]TELFDLK[136.11].T "sp|Q13948|CASP_HUMAN,sp|P39880|CUX1_HUMAN,tr|A0A2R8Y8D0|A0A2R8Y8D0_HUMAN,tr|A0A2R8Y852|A0A2R8Y852_HUMAN,tr|A0A2R8YDI1|A0A2R8YDI1_HUMAN" 5 1139.6305 1.01 49117 15313 2 1139.631671 570.8225 Protein CASP OS=Homo sapiens OX=9606 GN=CUX1 PE=1 SV=2 5.74 2764.1 - 984636 - - - 0.9889 - 1.897 0.271 - 398.7 1 2 1 0.0011 9 0 0 0 7.71E+06 7.67E+06 - - - 2.8946 1 221125_WJC_METTL3_EV_vs_WT_F04.15314.15314.2 4.25E-08 19/30 R.GQAAVQQLQAEGLSPR.F "sp|P16152|CBR1_HUMAN,sp|O75828|CBR3_HUMAN,tr|E9PQ63|E9PQ63_HUMAN,tr|A8MTM1|A8MTM1_HUMAN" 4 1651.8642 1.54 49118 15314 2 1651.863024 826.9394 Carbonyl reductase [NADPH] 1 OS=Homo sapiens OX=9606 GN=CBR1 PE=1 SV=3 6 2764.3 - 727948 - - - -0.701 - 3.738 0.609 - 1634.1 1 2 0 -0.0012 16 0 0 0 1.01E+07 6.57E+06 - - - 6.7804 1 221125_WJC_METTL3_EV_vs_WT_F04.15315.15315.2 5.49E-06 16/30 R.LIGPNC[160.03]PGVINPGEC[160.03]K.L "sp|P53597|SUCA_HUMAN,tr|A0A494C0D1|A0A494C0D1_HUMAN" 2 1723.8386 1.92 49119 15315 2 1723.839079 862.9266 "Succinate--CoA ligase [ADP\GDP-forming] subunit alpha, mitochondrial OS=Homo sapiens OX=9606 GN=SUCLG1 PE=1 SV=4" 5.99 2764.4 - 635767 - - - 0.2999 - 2.936 0.612 - 511.2 1 2 0 0.0005 16 0 0 0 2.51E+07 1.31E+07 - - - 6.209 1 221125_WJC_METTL3_EV_vs_WT_F04.15316.15316.2 1.90E-08 14/32 K.AVTAFSSTETGSAEGFK[136.11].S tr|A0A804HKC3|A0A804HKC3_HUMAN 1 1696.8035 4.39 49120 15316 2 1696.790203 849.409 Protein PRRC2B (Fragment) OS=Homo sapiens OX=9606 GN=PRRC2B PE=4 SV=1 4.53 2764.5 - 610339 - - - -7.8636 - 3.002 0.614 - 438.4 1 2 0 -0.0133 17 0 0 0 1.18E+07 2.68E+06 - - - 6.2744 0.999 221125_WJC_METTL3_EV_vs_WT_F04.15318.15318.2 2.12E-05 24-Oct K.YVGVSSDSVGGFR.Y sp|Q14677|EPN4_HUMAN 1 1328.6361 1.53 49122 15318 2 1328.641154 665.3253 Clathrin interactor 1 OS=Homo sapiens OX=9606 GN=CLINT1 PE=1 SV=1 5.84 2764.8 - 484095 - - - 3.819 - 1.897 0.564 - 231.6 1 2 0 0.0051 13 0 0 0 3.18E+06 2.09E+06 - - - 4.8484 0.9999 221125_WJC_METTL3_EV_vs_WT_F04.15319.15319.3 0.000102 Nov-40 R.DFDPVHGDVIK[136.11].H sp|P07948|LYN_HUMAN 1 1248.623 0.97 49123 15319 3 1248.624244 417.2149 Tyrosine-protein kinase Lyn OS=Homo sapiens OX=9606 GN=LYN PE=1 SV=3 4.41 2764.9 - 463955 - - - 0.9947 - 1.991 0.412 - 155.5 1 2 0 0.0012 11 0 0 0 4.44E+06 4.57E+06 - - - 5.0893 0.9999 221125_WJC_METTL3_EV_vs_WT_F04.15325.15325.2 5.52E-06 13/24 R.NTGIIC[160.03]TIGPASR[166.11].S "sp|P14618|KPYM_HUMAN,tr|H3BQ34|H3BQ34_HUMAN,tr|H3BTJ2|H3BTJ2_HUMAN,tr|B4DNK4|B4DNK4_HUMAN,tr|A0A804F6T5|A0A804F6T5_HUMAN,tr|H3BT25|H3BT25_HUMAN,tr|H3BUW1|H3BUW1_HUMAN,tr|H3BTN5|H3BTN5_HUMAN,tr|A0A804F729|A0A804F729_HUMAN,tr|H3BU13|H3BU13_HUMAN" 10 1368.7059 1.72 49128 15325 2 1368.707342 685.3602 Pyruvate kinase PKM OS=Homo sapiens OX=9606 GN=PKM PE=1 SV=4 8.25 2765.7 - 3.11E+06 - - - 1.0506 - 2.801 0.473 - 652 1 2 0 0.0014 13 0 0 0 7.97E+07 4.62E+07 - - - 5.1776 1 221125_WJC_METTL3_EV_vs_WT_F04.15327.15327.3 0.00259 Dec-36 R.SIHDALC[160.03]VIR[166.11].C "sp|P50991|TCPD_HUMAN,sp|P48643|TCPE_HUMAN,tr|E9PCA1|E9PCA1_HUMAN,tr|B7ZAR1|B7ZAR1_HUMAN,tr|E7ENZ3|E7ENZ3_HUMAN" 5 1192.6262 0.62 49130 15327 3 1192.625886 398.5493 T-complex protein 1 subunit delta OS=Homo sapiens OX=9606 GN=CCT4 PE=1 SV=4 6.46 2765.9 - 3.82E+06 - - - -0.2608 - 2.144 0.466 - 302.5 1 2 0 -0.0003 10 0 0 0 1.27E+07 2.04E+07 - - - 5.9627 0.9876 221125_WJC_METTL3_EV_vs_WT_F04.15328.15328.3 0.0622 13/52 R.QYELVVHTDIDAAK.V "sp|P16435|NCPR_HUMAN,tr|H0Y4R2|H0Y4R2_HUMAN" 2 1600.8097 2.67 49131 15328 3 1600.815504 534.6105 NADPH--cytochrome P450 reductase OS=Homo sapiens OX=9606 GN=POR PE=1 SV=2 4.54 2766 - 2.90E+06 - - - 3.6338 - 1.893 0.231 - 198 1 2 0 0.0058 14 0 0 0 1.78E+07 6.68E+06 - - - 2.8097 0.9999 221125_WJC_METTL3_EV_vs_WT_F04.15329.15329.3 0.00782 14/36 R.SIHDALC[160.03]VIR.C "sp|P50991|TCPD_HUMAN,sp|P48643|TCPE_HUMAN,tr|E9PCA1|E9PCA1_HUMAN,tr|B7ZAR1|B7ZAR1_HUMAN,tr|E7ENZ3|E7ENZ3_HUMAN" 5 1182.6179 0.59 49132 15329 3 1182.617404 395.2133 T-complex protein 1 subunit delta OS=Homo sapiens OX=9606 GN=CCT4 PE=1 SV=4 6.46 2766 - 2.27E+06 - - - -0.4422 - 2.079 0.427 - 402.1 1 2 0 -0.0005 10 0 0 0 1.27E+07 2.14E+07 - - - 5.4379 1 221125_WJC_METTL3_EV_vs_WT_F04.15332.15332.3 0.000141 17/48 K.EWIEC[160.03]AHGIGYTR.A sp|O43920|NDUS5_HUMAN 1 1590.7249 1.68 49135 15332 3 1590.72617 531.2489 NADH dehydrogenase [ubiquinone] iron-sulfur protein 5 OS=Homo sapiens OX=9606 GN=NDUFS5 PE=1 SV=3 5.4 2766.2 - 1.32E+06 - - - 0.7908 - 2.941 0.406 - 454 1 2 0 0.0013 13 0 0 0 5.42E+06 3.23E+06 - - - 5.991 0.9999 221125_WJC_METTL3_EV_vs_WT_F04.15334.15334.3 9.98E-08 15/48 R.AR[166.11]PPGPPDLGAFR[166.11].G sp|P50548|ERF_HUMAN 1 1369.737 3.56 49137 15334 3 1369.736153 457.5863 ETS domain-containing transcription factor ERF OS=Homo sapiens OX=9606 GN=ERF PE=1 SV=2 9.64 2766.4 - 1.12E+06 - - - -0.5877 - 2.816 0.406 - 260.2 1 2 0 -0.0008 13 0 0 0 4.02E+07 1.13E+07 - - - 5.8733 0.9999 221125_WJC_METTL3_EV_vs_WT_F04.15335.15335.2 5.05E-06 18-Nov R.SMQDVVEDYK.S sp|Q7Z794|K2C1B_HUMAN 1 1212.5333 9.98 49138 15335 2 1212.533447 607.2739 "Keratin, type II cytoskeletal 1b OS=Homo sapiens OX=9606 GN=KRT77 PE=1 SV=3" 4.03 2766.5 - 1.06E+06 - - - 0.1592 - 1.983 0.563 - 427.5 1 2 0 0.0002 10 0 0 0 7.21E+06 7.23E+05 - - - 5.1102 0.9986 221125_WJC_METTL3_EV_vs_WT_F04.15336.15336.3 0.000463 Dec-36 K.SK[136.11]GIAYIEFK[136.11].T "sp|P19338|NUCL_HUMAN,tr|A0A7I2V506|A0A7I2V506_HUMAN,tr|A0A7I2V2U7|A0A7I2V2U7_HUMAN,tr|A0A7I2V3F3|A0A7I2V3F3_HUMAN,tr|A0A7I2V428|A0A7I2V428_HUMAN,tr|A0A7I2V349|A0A7I2V349_HUMAN,tr|H7BY16|H7BY16_HUMAN,tr|A0A7I2V5M5|A0A7I2V5M5_HUMAN,tr|C9JLB1|C9JLB1_HUMAN" 9 1170.662 3.26 49139 15336 3 1170.662212 391.2279 Nucleolin OS=Homo sapiens OX=9606 GN=NCL PE=1 SV=3 8.22 2766.6 - 954128 - - - 0.2153 - 1.98 0.328 - 187.8 1 2 1 0.0003 10 0 0 0 1.56E+07 4.78E+06 - - - 4.1917 1 221125_WJC_METTL3_EV_vs_WT_F04.15338.15338.3 5.75E-11 17/40 A.PEEEDHVLVLR.K "sp|P07237|PDIA1_HUMAN,tr|A0A7P0TA97|A0A7P0TA97_HUMAN,tr|A0A7P0T8C0|A0A7P0T8C0_HUMAN,tr|H7BZ94|H7BZ94_HUMAN,tr|A0A7P0Z4B2|A0A7P0Z4B2_HUMAN,tr|A0A7P0TA71|A0A7P0TA71_HUMAN,tr|I3L4M2|I3L4M2_HUMAN,tr|A0A7P0T9D6|A0A7P0T9D6_HUMAN,tr|A0A7P0T9K9|A0A7P0T9K9_HUMAN,tr|H0Y3Z3|H0Y3Z3_HUMAN,tr|A0A7P0Z4S2|A0A7P0Z4S2_HUMAN,tr|I3NI03|I3NI03_HUMAN,tr|A0A7P0TA35|A0A7P0TA35_HUMAN,tr|A0A7P0TAX9|A0A7P0TAX9_HUMAN,tr|I3L1Y5|I3L1Y5_HUMAN,tr|I3L514|I3L514_HUMAN,tr|A0A7P0Z476|A0A7P0Z476_HUMAN,tr|A0A7P0Z4F8|A0A7P0Z4F8_HUMAN,tr|A0A7P0TBP8|A0A7P0TBP8_HUMAN,tr|A0A7P0TB26|A0A7P0TB26_HUMAN,tr|A0A7P0T9U6|A0A7P0T9U6_HUMAN,tr|A0A7P0T9E3|A0A7P0T9E3_HUMAN,tr|A0A7P0TBA3|A0A7P0TBA3_HUMAN,tr|I3L0S0|I3L0S0_HUMAN,tr|I3L3P5|I3L3P5_HUMAN,tr|A0A7P0T940|A0A7P0T940_HUMAN,tr|A0A7P0T8J3|A0A7P0T8J3_HUMAN,tr|A0A7P0Z4J0|A0A7P0Z4J0_HUMAN,tr|A0A7P0T9S9|A0A7P0T9S9_HUMAN,tr|A0A7P0T8X1|A0A7P0T8X1_HUMAN,tr|I3L3U6|I3L3U6_HUMAN" 31 1334.683 0.77 49141 15338 3 1334.682956 445.9016 Protein disulfide-isomerase OS=Homo sapiens OX=9606 GN=P4HB PE=1 SV=3 4.4 2766.8 - 759805 - - - -0.0554 - 2.794 0.642 - 539.2 1 1 0 -0.0001 11 0 0 0 5.46E+06 7.10E+06 - - - 8.6165 1 221125_WJC_METTL3_EV_vs_WT_F04.15340.15340.2 1.65E-05 15/24 A.DAPEEEDHVLVLR.K "sp|P07237|PDIA1_HUMAN,tr|A0A7P0TA97|A0A7P0TA97_HUMAN,tr|A0A7P0T8C0|A0A7P0T8C0_HUMAN,tr|H7BZ94|H7BZ94_HUMAN,tr|A0A7P0Z4B2|A0A7P0Z4B2_HUMAN,tr|A0A7P0TA71|A0A7P0TA71_HUMAN,tr|I3L4M2|I3L4M2_HUMAN,tr|A0A7P0T9D6|A0A7P0T9D6_HUMAN,tr|A0A7P0T9K9|A0A7P0T9K9_HUMAN,tr|H0Y3Z3|H0Y3Z3_HUMAN,tr|A0A7P0Z4S2|A0A7P0Z4S2_HUMAN,tr|I3NI03|I3NI03_HUMAN,tr|A0A7P0TA35|A0A7P0TA35_HUMAN,tr|A0A7P0TAX9|A0A7P0TAX9_HUMAN,tr|I3L1Y5|I3L1Y5_HUMAN,tr|I3L514|I3L514_HUMAN,tr|A0A7P0Z476|A0A7P0Z476_HUMAN,tr|A0A7P0Z4F8|A0A7P0Z4F8_HUMAN,tr|A0A7P0TBP8|A0A7P0TBP8_HUMAN,tr|A0A7P0TB26|A0A7P0TB26_HUMAN,tr|A0A7P0T9U6|A0A7P0T9U6_HUMAN,tr|A0A7P0T9E3|A0A7P0T9E3_HUMAN,tr|A0A7P0TBA3|A0A7P0TBA3_HUMAN,tr|I3L0S0|I3L0S0_HUMAN,tr|I3L3P5|I3L3P5_HUMAN,tr|A0A7P0T940|A0A7P0T940_HUMAN,tr|A0A7P0T8J3|A0A7P0T8J3_HUMAN,tr|A0A7P0Z4J0|A0A7P0Z4J0_HUMAN,tr|A0A7P0T9S9|A0A7P0T9S9_HUMAN,tr|A0A7P0T8X1|A0A7P0T8X1_HUMAN,tr|I3L3U6|I3L3U6_HUMAN" 31 1520.7471 2.42 49143 15340 2 1520.74731 761.3808 Protein disulfide-isomerase OS=Homo sapiens OX=9606 GN=P4HB PE=1 SV=3 4.17 2767.1 - 634254 - - - 0.1466 - 2.812 0.604 - 664 1 1 0 0.0002 13 0 0 0 5.85E+06 2.42E+06 - - - 6.1556 1 221125_WJC_METTL3_EV_vs_WT_F04.15341.15341.2 1.86E-08 17/30 K.SELVANNVTLPAGEQR[166.11].K "sp|P42166|LAP2A_HUMAN,sp|P42167|LAP2B_HUMAN,tr|G5E972|G5E972_HUMAN" 3 1706.8827 -1 49144 15341 2 1706.882156 854.4486 "Lamina-associated polypeptide 2, isoform alpha OS=Homo sapiens OX=9606 GN=TMPO PE=1 SV=2" 4.53 2767.2 - 558769 - - - -0.3087 - 3.098 0.599 - 821 1 2 0 -0.0005 16 0 0 0 0.00E+00 0.00E+00 - - - 6.2451 0.8092 221125_WJC_METTL3_EV_vs_WT_F04.15343.15343.3 0.0135 Oct-40 R.DFDPVHGDVIK.H sp|P07948|LYN_HUMAN 1 1240.6088 1.05 49146 15343 3 1240.609009 414.5435 Tyrosine-protein kinase Lyn OS=Homo sapiens OX=9606 GN=LYN PE=1 SV=3 4.41 2767.4 - 501734 - - - 0.1669 - 1.68 0.015 - 85.3 2 2 0 0.0002 11 0 0 0 4.85E+06 4.63E+06 - - - 0.0417 1 221125_WJC_METTL3_EV_vs_WT_F04.15344.15344.2 1.90E-06 20-Dec K.YDSDGVWDPEK[136.11].W "sp|Q9NRA8|4ET_HUMAN,tr|B1AKL5|B1AKL5_HUMAN,tr|B1AKL4|B1AKL4_HUMAN" 3 1317.5605 1.52 49147 15344 2 1317.561834 659.7875 Eukaryotic translation initiation factor 4E transporter OS=Homo sapiens OX=9606 GN=EIF4ENIF1 PE=1 SV=2 3.84 2767.6 - 498041 - - - 1.0413 - 2.192 0.646 - 334.3 1 2 0 0.0014 11 0 0 0 8.60E+06 5.65E+06 - - - 5.935 0.9999 221125_WJC_METTL3_EV_vs_WT_F04.15346.15346.3 3.49E-08 16/60 R.LIGPNC[160.03]PGVINPGEC[160.03]K.L "sp|P53597|SUCA_HUMAN,tr|A0A494C0D1|A0A494C0D1_HUMAN" 2 1723.8386 2.17 49148 15346 3 1723.841258 575.6201 "Succinate--CoA ligase [ADP\GDP-forming] subunit alpha, mitochondrial OS=Homo sapiens OX=9606 GN=SUCLG1 PE=1 SV=4" 5.99 2767.8 - 751915 - - - 1.564 - 2.978 0.439 - 155.5 1 2 0 0.0027 16 0 0 0 8.13E+06 3.74E+06 - - - 6.2337 1 221125_WJC_METTL3_EV_vs_WT_F04.15350.15350.2 7.08E-08 17/30 K.SELVANNVTLPAGEQR.K "sp|P42166|LAP2A_HUMAN,sp|P42167|LAP2B_HUMAN,tr|G5E972|G5E972_HUMAN" 3 1696.8744 1.41 49152 15350 2 1696.875182 849.4445 "Lamina-associated polypeptide 2, isoform alpha OS=Homo sapiens OX=9606 GN=TMPO PE=1 SV=2" 4.53 2768.2 - 1.12E+06 - - - 0.4532 - 3.132 0.623 - 895.7 1 2 0 0.0008 16 0 0 0 6.52E+06 4.61E+06 - - - 6.4491 0.9999 221125_WJC_METTL3_EV_vs_WT_F04.15351.15351.2 0.000278 14-Sep K.QYFEQFGK[136.11].V "sp|O43347|MSI1H_HUMAN,sp|Q96DH6|MSI2H_HUMAN,tr|B4DHE8|B4DHE8_HUMAN,tr|H0YHB7|H0YHB7_HUMAN,tr|A0A6Q8PF05|A0A6Q8PF05_HUMAN,tr|B4DM51|B4DM51_HUMAN,tr|J3KTC1|J3KTC1_HUMAN" 7 1053.5011 1.39 49153 15351 2 1053.501304 527.7578 RNA-binding protein Musashi homolog 1 OS=Homo sapiens OX=9606 GN=MSI1 PE=1 SV=1 6 2768.3 - 951856 - - - 0.1974 - 1.614 0.558 - 256.7 1 2 0 0.0002 8 0 0 0 5.15E+06 3.70E+06 - - - 4.6061 1 221125_WJC_METTL3_EV_vs_WT_F04.15352.15352.2 1.66E-08 15/30 R.LIGPNC[160.03]PGVINPGEC[160.03]K[136.11].L "sp|P53597|SUCA_HUMAN,tr|A0A494C0D1|A0A494C0D1_HUMAN" 2 1731.8528 1.9 49154 15352 2 1731.855041 866.9337 "Succinate--CoA ligase [ADP\GDP-forming] subunit alpha, mitochondrial OS=Homo sapiens OX=9606 GN=SUCLG1 PE=1 SV=4" 5.99 2768.4 - 933233 - - - 1.3159 - 2.774 0.63 - 463.8 1 2 0 0.0023 16 0 0 0 2.49E+07 1.31E+07 - - - 6.2019 0.9996 221125_WJC_METTL3_EV_vs_WT_F04.15353.15353.2 0.00104 18-Sep R.DQSTYISAIR[166.11].E "sp|Q9UBU9|NXF1_HUMAN,tr|E9PIN3|E9PIN3_HUMAN" 2 1162.5858 1.14 49155 15353 2 1162.586361 582.3002 Nuclear RNA export factor 1 OS=Homo sapiens OX=9606 GN=NXF1 PE=1 SV=1 5.84 2768.6 - 931530 - - - 0.5066 - 1.85 0.353 - 341.1 1 2 0 0.0006 10 0 0 0 8.06E+06 7.10E+06 - - - 3.3652 1 221125_WJC_METTL3_EV_vs_WT_F04.15354.15354.2 6.58E-08 14/20 K.YDSDGVWDPEK.W "sp|Q9NRA8|4ET_HUMAN,tr|B1AKL5|B1AKL5_HUMAN,tr|B1AKL4|B1AKL4_HUMAN" 3 1309.5463 1.52 49156 15354 2 1309.544241 655.7804 Eukaryotic translation initiation factor 4E transporter OS=Homo sapiens OX=9606 GN=EIF4ENIF1 PE=1 SV=2 3.84 2768.7 - 848632 - - - -1.5433 - 2.426 0.691 - 509.2 1 2 0 -0.002 11 0 0 0 8.60E+06 5.65E+06 - - - 6.5416 1 221125_WJC_METTL3_EV_vs_WT_F04.15355.15355.3 1.04E-07 17/52 K.NLLHVTDTGVGMTR.E "sp|P14625|ENPL_HUMAN,tr|A0A7P0T917|A0A7P0T917_HUMAN,tr|A0A7P0T823|A0A7P0T823_HUMAN,tr|A0A7P0TAE1|A0A7P0TAE1_HUMAN,tr|H0YIV0|H0YIV0_HUMAN,tr|A0A7P0T8R3|A0A7P0T8R3_HUMAN,tr|A0A7P0T885|A0A7P0T885_HUMAN,tr|A0A7P0TAY2|A0A7P0TAY2_HUMAN,tr|A0A087WT78|A0A087WT78_HUMAN,tr|A0A7P0TBC2|A0A7P0TBC2_HUMAN,tr|A0A7P0TAT8|A0A7P0TAT8_HUMAN" 11 1512.7719 19.62 49157 15355 3 1512.771178 505.2646 Endoplasmin OS=Homo sapiens OX=9606 GN=HSP90B1 PE=1 SV=1 6.74 2768.8 - 836342 - - - -0.4522 - 3.385 0.605 - 315.5 1 2 0 -0.0007 14 0 0 0 6.24E+06 3.18E+05 - - - 8.5254 0.9719 221125_WJC_METTL3_EV_vs_WT_F04.15356.15356.3 6.34E-06 13/64 L.GPPPPSFHLGGPAVGPR.G "sp|P43243|MATR3_HUMAN,tr|D6RE02|D6RE02_HUMAN,tr|B3KM87|B3KM87_HUMAN,tr|A8MXP9|A8MXP9_HUMAN,tr|D6RAY2|D6RAY2_HUMAN,tr|D6R991|D6R991_HUMAN,tr|A0A0R4J2E8|A0A0R4J2E8_HUMAN,tr|D6RAM9|D6RAM9_HUMAN,tr|D6RIA2|D6RIA2_HUMAN,tr|H0Y8T4|H0Y8T4_HUMAN,tr|D6REM6|D6REM6_HUMAN,tr|D6RBI2|D6RBI2_HUMAN" 12 1638.8631 0.73 49158 15356 3 1638.869239 547.295 Matrin-3 OS=Homo sapiens OX=9606 GN=MATR3 PE=1 SV=2 9.76 2768.9 - 585979 - - - 3.7703 - 2.554 0.469 - 124.1 1 1 0 0.0062 17 0 0 0 2.66E+06 3.66E+06 - - - 6.136 0.9733 221125_WJC_METTL3_EV_vs_WT_F04.15357.15357.3 0.288 Aug-40 K.VPPEFDFSAHK.Y sp|Q5VZE5|NAA35_HUMAN 1 1272.6139 4.35 49159 15357 3 1272.612968 425.2119 "N-alpha-acetyltransferase 35, NatC auxiliary subunit OS=Homo sapiens OX=9606 GN=NAA35 PE=1 SV=1" 5.32 2769 - 520374 - - - -0.7229 - 1.274 0.214 - 35.7 7 2 0 -0.0009 11 0 0 0 1.92E+07 4.41E+06 - - - 1.2224 0.9997 221125_WJC_METTL3_EV_vs_WT_F04.15358.15358.2 0.000569 30-Dec R.ASPNLIGATGANSLGK.V sp|Q02078|MEF2A_HUMAN 1 1469.7838 0.96 49160 15358 2 1469.784028 735.8992 Myocyte-specific enhancer factor 2A OS=Homo sapiens OX=9606 GN=MEF2A PE=1 SV=1 8.8 2769.2 - 476762 - - - 0.1504 - 2.039 0.396 - 293.6 1 2 0 0.0002 16 0 0 0 2.43E+06 2.53E+06 - - - 3.7174 0.9981 221125_WJC_METTL3_EV_vs_WT_F04.15360.15360.2 0.000208 22-Sep R.DGWPAMGIHGDK[136.11].S "sp|P17844|DDX5_HUMAN,tr|A0A7I2V5F5|A0A7I2V5F5_HUMAN,tr|A0A7I2V507|A0A7I2V507_HUMAN,tr|J3KTA4|J3KTA4_HUMAN,tr|A0A0G2JLI4|A0A0G2JLI4_HUMAN,tr|A0A7I2V2S0|A0A7I2V2S0_HUMAN" 6 1290.5907 1.7 49162 15360 2 1290.586894 646.3026 Probable ATP-dependent RNA helicase DDX5 OS=Homo sapiens OX=9606 GN=DDX5 PE=1 SV=1 5.21 2769.4 - 419722 - - - -2.9149 - 1.535 0.399 - 133.4 1 2 0 -0.0038 12 0 0 0 1.34E+07 7.88E+06 - - - 3.1144 0.9994 221125_WJC_METTL3_EV_vs_WT_F04.15362.15362.2 0.000658 20-Nov R.QYDQEIENLEK[136.11].Q sp|Q9H2G2|SLK_HUMAN 1 1415.666 0.001 49164 15362 2 1415.662561 708.8403 STE20-like serine\threonine-protein kinase OS=Homo sapiens OX=9606 GN=SLK PE=1 SV=1 4 2769.7 - 281463 - - - -2.4215 - 2.112 0.397 - 472 1 2 0 -0.0034 11 0 0 0 0.00E+00 2.85E+06 - - - 3.9947 0.9998 221125_WJC_METTL3_EV_vs_WT_F04.15363.15363.2 0.00134 13/28 K.SVEVQGETETIIATK[136.11].T sp|O60763|USO1_HUMAN 1 1611.8447 2.53 49165 15363 2 1611.841436 806.9296 General vesicular transport factor p115 OS=Homo sapiens OX=9606 GN=USO1 PE=1 SV=2 4.25 2769.8 - 276056 - - - -2.0138 - 2.472 0.556 - 519.4 1 2 0 -0.0032 15 0 0 0 4.27E+06 1.69E+06 - - - 5.3716 1 221125_WJC_METTL3_EV_vs_WT_F04.15367.15367.2 0.00018 14/24 R.FSGSGSGTDFTLK.L "sp|A2NJV5|KV229_HUMAN,sp|A0A087WW87|KV240_HUMAN,sp|P06310|KV230_HUMAN,sp|A0A075B6S2|KVD29_HUMAN,sp|P01614|KVD40_HUMAN,sp|P01615|KVD28_HUMAN,sp|A0A075B6S6|KVD30_HUMAN,sp|A0A075B6P5|KV228_HUMAN,sp|A0A0A0MRZ7|KVD26_HUMAN" 9 1302.6092 6292.02 49168 15367 2 1302.609525 652.3119 Immunoglobulin kappa variable 2-29 OS=Homo sapiens OX=9606 GN=IGKV2-29 PE=3 SV=2 5.84 2770.3 - 1.37E+07 - - - 0.2526 - 2.759 0.637 - 432.2 1 2 0 0.0003 13 0 0 0 9.80E+08 1.56E+05 - - - 6.3505 0.9999 221125_WJC_METTL3_EV_vs_WT_F04.15368.15368.2 1.39E-07 28-Dec R.IYNISGNGSPLADSK.E sp|Q53HL2|BOREA_HUMAN 1 1534.7627 2.11 49169 15368 2 1534.76306 768.3886 Borealin OS=Homo sapiens OX=9606 GN=CDCA8 PE=1 SV=2 5.83 2770.4 - 2.19E+06 - - - 0.2105 - 2.551 0.537 - 509.1 1 2 0 0.0003 15 0 0 0 1.64E+07 7.76E+06 - - - 5.3096 0.9998 221125_WJC_METTL3_EV_vs_WT_F04.15371.15371.3 9.42E-06 Dec-68 K.LLSASQLSAEEEEEKQAE.- sp|P17509|HXB6_HUMAN 1 1989.9379 3.58 49172 15371 3 1989.940165 664.3199 Homeobox protein Hox-B6 OS=Homo sapiens OX=9606 GN=HOXB6 PE=1 SV=4 4.09 2770.6 - 1.61E+06 - - - 1.1583 - 2.375 0.486 - 132.1 1 2 1 0.0023 18 0 0 0 6.36E+06 1.78E+06 - - - 6.1117 0.9999 221125_WJC_METTL3_EV_vs_WT_F04.15372.15372.3 1.41E-05 17/52 R.LQDEIQNMK[136.11]EEMAR[166.11].H "sp|P08670|VIME_HUMAN,tr|B0YJC5|B0YJC5_HUMAN,tr|B0YJC4|B0YJC4_HUMAN" 3 1751.8301 2.04 49173 15372 3 1751.830113 584.9507 Vimentin OS=Homo sapiens OX=9606 GN=VIM PE=1 SV=4 4.41 2770.6 - 1.50E+06 - - - -0.0068 - 2.884 0.582 - 214.3 1 2 1 0 14 0 0 0 1.53E+07 7.51E+06 - - - 7.8435 1 221125_WJC_METTL3_EV_vs_WT_F04.15374.15374.3 1.49E-08 16/80 K.LYGSAGPPPTGEEDTAEK[136.11]DEL.- "sp|P11021|BIP_HUMAN,tr|A0A7P0TB36|A0A7P0TB36_HUMAN,tr|A0A7P0TAI0|A0A7P0TAI0_HUMAN" 3 2182.9997 0.66 49175 15374 3 2183.001403 728.6739 Endoplasmic reticulum chaperone BiP OS=Homo sapiens OX=9606 GN=HSPA5 PE=1 SV=2 3.77 2770.9 - 987531 - - - 0.7623 - 3.357 0.598 - 191.8 1 2 1 0.0017 21 0 0 0 1.12E+07 1.71E+07 - - - 8.1101 0.9999 221125_WJC_METTL3_EV_vs_WT_F04.15375.15375.3 0.000116 Dec-60 K.SELVANNVTLPAGEQR.K "sp|P42166|LAP2A_HUMAN,sp|P42167|LAP2B_HUMAN,tr|G5E972|G5E972_HUMAN" 3 1696.8744 1.14 49176 15375 3 1696.877211 566.6321 "Lamina-associated polypeptide 2, isoform alpha OS=Homo sapiens OX=9606 GN=TMPO PE=1 SV=2" 4.53 2770.9 - 783418 - - - 1.6489 - 2.495 0.408 - 173.8 1 2 0 0.0028 16 0 0 0 3.09E+06 2.70E+06 - - - 5.434 1 221125_WJC_METTL3_EV_vs_WT_F04.15376.15376.2 2.76E-10 14/34 K.LLSASQLSAEEEEEKQAE.- sp|P17509|HXB6_HUMAN 1 1989.9379 2.35 49177 15376 2 1989.94039 995.9762 Homeobox protein Hox-B6 OS=Homo sapiens OX=9606 GN=HOXB6 PE=1 SV=4 4.09 2771.1 - 740770 - - - 1.2714 - 3.152 0.719 - 489.7 1 2 1 0.0025 18 0 0 0 3.27E+06 1.39E+06 - - - 7.1732 0.9999 221125_WJC_METTL3_EV_vs_WT_F04.15378.15378.3 8.01E-06 16/56 R.LLSSVTAELPEDK[136.11]PR[166.11].L sp|Q9H974|QTRT2_HUMAN 1 1671.9162 1.99 49179 15378 3 1671.921928 558.3127 Queuine tRNA-ribosyltransferase accessory subunit 2 OS=Homo sapiens OX=9606 GN=QTRT2 PE=1 SV=1 4.68 2771.3 - 646952 - - - 3.4134 - 2.882 0.49 - 366.8 1 2 0 0.0057 15 0 0 0 6.54E+06 3.28E+06 - - - 6.7634 0.9989 221125_WJC_METTL3_EV_vs_WT_F04.15379.15379.2 1.15E-07 Nov-40 K.LYGSAGPPPTGEEDTAEK[136.11]DEL.- "sp|P11021|BIP_HUMAN,tr|A0A7P0TB36|A0A7P0TB36_HUMAN,tr|A0A7P0TAI0|A0A7P0TAI0_HUMAN" 3 2182.9997 0.6 49180 15379 2 2182.998408 1092.5071 Endoplasmic reticulum chaperone BiP OS=Homo sapiens OX=9606 GN=HSPA5 PE=1 SV=2 3.77 2771.4 - 626137 - - - -0.6097 - 2.114 0.6 - 213.7 1 2 1 -0.0013 21 0 0 0 6.62E+06 1.11E+07 - - - 5.3126 0.9999 221125_WJC_METTL3_EV_vs_WT_F04.15380.15380.3 7.56E-05 Oct-60 K.SELVANNVTLPAGEQR[166.11].K "sp|P42166|LAP2A_HUMAN,sp|P42167|LAP2B_HUMAN,tr|G5E972|G5E972_HUMAN" 3 1706.8827 1.49 49181 15380 3 1706.881244 569.9682 "Lamina-associated polypeptide 2, isoform alpha OS=Homo sapiens OX=9606 GN=TMPO PE=1 SV=2" 4.53 2771.5 - 478204 - - - -0.8431 - 2.32 0.399 - 102.9 1 2 0 -0.0014 16 0 0 0 3.09E+06 2.07E+06 - - - 5.1474 1 221125_WJC_METTL3_EV_vs_WT_F04.15381.15381.3 3.35E-06 17/48 K.EVESPYEVHDYIR.A "sp|Q6Y7W6|GGYF2_HUMAN,tr|A0A7I2V3H7|A0A7I2V3H7_HUMAN,tr|I1E4Y6|I1E4Y6_HUMAN,tr|A0A7I2V516|A0A7I2V516_HUMAN,tr|A0A7I2V3H0|A0A7I2V3H0_HUMAN,tr|A0A7I2V361|A0A7I2V361_HUMAN" 6 1634.7577 2.4 49182 15381 3 1634.76143 545.9265 GRB10-interacting GYF protein 2 OS=Homo sapiens OX=9606 GN=GIGYF2 PE=1 SV=1 4.4 2771.7 - 462831 - - - 2.3117 - 2.949 0.586 - 476.7 1 2 0 0.0038 13 0 0 0 1.00E+08 4.17E+07 - - - 8.0044 1 221125_WJC_METTL3_EV_vs_WT_F04.15382.15382.3 5.40E-08 14/60 K.IFVGGIPHNC[160.03]GETELR[166.11].E "sp|Q96EP5|DAZP1_HUMAN,tr|K7EK33|K7EK33_HUMAN,tr|K7EQ55|K7EQ55_HUMAN,tr|K7EQ02|K7EQ02_HUMAN" 4 1807.8915 1.66 49183 15382 3 1807.893235 603.6378 DAZ-associated protein 1 OS=Homo sapiens OX=9606 GN=DAZAP1 PE=1 SV=1 5.4 2771.8 - 433806 - - - 0.9746 - 2.492 0.562 - 229.8 1 2 0 0.0018 16 0 0 0 1.56E+07 9.43E+06 - - - 7.1481 1 221125_WJC_METTL3_EV_vs_WT_F04.15384.15384.2 5.92E-07 13/40 K.LYGSAGPPPTGEEDTAEKDEL.- "sp|P11021|BIP_HUMAN,tr|A0A7P0TB36|A0A7P0TB36_HUMAN,tr|A0A7P0TAI0|A0A7P0TAI0_HUMAN" 3 2174.9855 0.65 49185 15384 2 2174.985788 1088.5 Endoplasmic reticulum chaperone BiP OS=Homo sapiens OX=9606 GN=HSPA5 PE=1 SV=2 3.77 2772.1 - 290447 - - - 0.1145 - 2.336 0.684 - 341.4 1 2 1 0.0002 21 0 0 0 2.44E+07 3.77E+07 - - - 6.1789 0.9997 221125_WJC_METTL3_EV_vs_WT_F04.15385.15385.2 4.62E-05 15/28 K.IQQLTALGAAQATAK[136.11].A "sp|Q99471|PFD5_HUMAN,tr|H3BMQ1|H3BMQ1_HUMAN,tr|H3BPF6|H3BPF6_HUMAN,tr|F8VNW6|F8VNW6_HUMAN,tr|A0A0D9SFR8|A0A0D9SFR8_HUMAN" 5 1491.85 1.05 49186 15385 2 1491.853726 746.9323 Prefoldin subunit 5 OS=Homo sapiens OX=9606 GN=PFDN5 PE=1 SV=2 8.75 2772.2 - 284444 - - - 2.4694 - 3.037 0.507 - 793.1 1 2 0 0.0037 15 0 0 0 1.77E+06 1.69E+06 - - - 5.5157 0.9999 221125_WJC_METTL3_EV_vs_WT_F04.15386.15386.2 6.12E-06 30-Oct K.LEESSTIGQDQTLMER.D "sp|Q96SB4|SRPK1_HUMAN,tr|H3BLV9|H3BLV9_HUMAN,tr|D6RBF8|D6RBF8_HUMAN" 3 1835.8571 -1 49187 15386 2 1835.85962 918.9358 SRSF protein kinase 1 OS=Homo sapiens OX=9606 GN=SRPK1 PE=1 SV=2 4 2772.3 - 252162 - - - 1.3683 - 2.707 0.561 - 248.9 1 2 0 0.0025 16 0 0 0 0.00E+00 0.00E+00 - - - 5.6321 0.9998 221125_WJC_METTL3_EV_vs_WT_F04.15388.15388.3 7.70E-05 15/52 K.AQIHDLVLVGGSTR.L "sp|P0DMV8|HS71A_HUMAN,sp|P0DMV9|HS71B_HUMAN,tr|V9GZ37|V9GZ37_HUMAN,tr|A0A0G2JIW1|A0A0G2JIW1_HUMAN" 4 1464.8049 0.27 49188 15388 3 1464.800748 489.2756 Heat shock 70 kDa protein 1A OS=Homo sapiens OX=9606 GN=HSPA1A PE=1 SV=1 6.79 2772.5 - 4.45E+06 - - - -2.8181 - 2.447 0.44 - 274.8 1 2 0 -0.0041 14 0 0 0 3.13E+09 1.15E+10 - - - 5.8225 0.9995 221125_WJC_METTL3_EV_vs_WT_F04.15390.15390.2 0.00327 22-Oct K.EQALADLNSVER.S "sp|O75410|TACC1_HUMAN,tr|E7EVI4|E7EVI4_HUMAN,tr|B4E3H6|B4E3H6_HUMAN,tr|H0YAY0|H0YAY0_HUMAN,tr|H0YBT8|H0YBT8_HUMAN,tr|E7ET87|E7ET87_HUMAN" 6 1343.6681 1.28 49190 15390 2 1343.669404 672.8413 Transforming acidic coiled-coil-containing protein 1 OS=Homo sapiens OX=9606 GN=TACC1 PE=1 SV=2 4.14 2772.6 - 5.18E+06 - - - 0.9645 - 2.113 0.301 - 384.5 1 2 0 0.0013 12 0 0 0 3.39E+07 2.64E+07 - - - 3.2322 1 221125_WJC_METTL3_EV_vs_WT_F04.15391.15391.3 1.16E-07 15/52 R.LQDEIQNMKEEMAR.H "sp|P08670|VIME_HUMAN,tr|B0YJC5|B0YJC5_HUMAN,tr|B0YJC4|B0YJC4_HUMAN" 3 1733.8077 2.02 49191 15391 3 1733.807683 578.9432 Vimentin OS=Homo sapiens OX=9606 GN=VIM PE=1 SV=4 4.41 2772.7 - 3.71E+06 - - - 0.0161 - 3.072 0.597 - 413.9 1 2 1 0 14 0 0 0 1.53E+07 7.61E+06 - - - 8.1786 1 221125_WJC_METTL3_EV_vs_WT_F04.15392.15392.2 0.000216 15/28 R.DGSLASNPYSGDLTK.F "sp|Q14157|UBP2L_HUMAN,tr|F8W726|F8W726_HUMAN,tr|H7C2T8|H7C2T8_HUMAN,tr|H0Y5H6|H0Y5H6_HUMAN" 4 1523.7104 2.31 49192 15392 2 1523.710283 762.8625 Ubiquitin-associated protein 2-like OS=Homo sapiens OX=9606 GN=UBAP2L PE=1 SV=2 4.21 2772.8 - 1.80E+06 - - - -0.0551 - 2.777 0.606 - 639.5 1 2 0 -0.0001 15 0 0 0 8.52E+08 3.69E+08 - - - 6.028 0.9999 221125_WJC_METTL3_EV_vs_WT_F04.15393.15393.3 0.00108 Dec-52 K.MVDPEK[136.11]PQLGMIDR[166.11].W "sp|P09874|PARP1_HUMAN,tr|A0A7I2V5E9|A0A7I2V5E9_HUMAN,tr|A0A7I2V625|A0A7I2V625_HUMAN,tr|A0A7I2V3E1|A0A7I2V3E1_HUMAN" 4 1645.8287 1.09 49193 15393 3 1645.829555 549.6168 Poly [ADP-ribose] polymerase 1 OS=Homo sapiens OX=9606 GN=PARP1 PE=1 SV=4 4.56 2772.8 - 1.72E+06 - - - 0.5389 - 2.293 0.427 - 151.7 1 2 0 0.0009 14 0 0 0 9.58E+06 8.77E+06 - - - 5.5058 1 221125_WJC_METTL3_EV_vs_WT_F04.15396.15396.3 4.98E-09 19/56 R.LLSSVTAELPEDKPR.L sp|Q9H974|QTRT2_HUMAN 1 1653.8938 2.03 49196 15396 3 1653.897711 552.3052 Queuine tRNA-ribosyltransferase accessory subunit 2 OS=Homo sapiens OX=9606 GN=QTRT2 PE=1 SV=1 4.68 2773 - 1.26E+06 - - - 2.3943 - 3.448 0.59 - 525 1 2 0 0.004 15 0 0 0 6.66E+06 3.28E+06 - - - 8.3467 0.9999 221125_WJC_METTL3_EV_vs_WT_F04.15397.15397.3 0.00817 15/40 R.INEILSNALKR.G "sp|P52272|HNRPM_HUMAN,tr|M0R019|M0R019_HUMAN,tr|A0A087X0X3|A0A087X0X3_HUMAN" 3 1269.7405 1.93 49197 15397 3 1269.741237 424.2541 Heterogeneous nuclear ribonucleoprotein M OS=Homo sapiens OX=9606 GN=HNRNPM PE=1 SV=3 8.75 2773.1 - 1.15E+06 - - - 0.5922 - 2.705 0.371 - 413.8 1 2 0 0.0008 11 0 0 0 1.69E+07 8.73E+06 - - - 5.503 1 221125_WJC_METTL3_EV_vs_WT_F04.15398.15398.2 1.33E-06 15/28 R.DGSLASNPYSGDLTK[136.11].F "sp|Q14157|UBP2L_HUMAN,tr|F8W726|F8W726_HUMAN,tr|H7C2T8|H7C2T8_HUMAN,tr|H0Y5H6|H0Y5H6_HUMAN" 4 1531.7246 2.31 49198 15398 2 1531.720517 766.8696 Ubiquitin-associated protein 2-like OS=Homo sapiens OX=9606 GN=UBAP2L PE=1 SV=2 4.21 2773.2 - 866216 - - - -2.6441 - 2.787 0.592 - 754 1 2 0 -0.004 15 0 0 0 8.52E+08 3.69E+08 - - - 5.9322 0.9999 221125_WJC_METTL3_EV_vs_WT_F04.15400.15400.3 8.73E-08 14/80 K.LYGSAGPPPTGEEDTAEKDEL.- "sp|P11021|BIP_HUMAN,tr|A0A7P0TB36|A0A7P0TB36_HUMAN,tr|A0A7P0TAI0|A0A7P0TAI0_HUMAN" 3 2174.9855 0.65 49200 15400 3 2174.986849 726.0025 Endoplasmic reticulum chaperone BiP OS=Homo sapiens OX=9606 GN=HSPA5 PE=1 SV=2 3.77 2773.5 - 806269 - - - 0.6023 - 3.289 0.576 - 132.4 1 2 1 0.0013 21 0 0 0 3.38E+07 5.22E+07 - - - 7.8158 0.9999 221125_WJC_METTL3_EV_vs_WT_F04.15401.15401.2 0.00137 20-Nov K.EEEWDPEYTPK.S "sp|Q9NYF8|BCLF1_HUMAN,sp|Q9Y2W1|TR150_HUMAN,tr|A0A3B3ITZ9|A0A3B3ITZ9_HUMAN,tr|H0YF14|H0YF14_HUMAN" 4 1421.5987 2.58 49201 15401 2 1421.60018 711.8066 Bcl-2-associated transcription factor 1 OS=Homo sapiens OX=9606 GN=BCLAF1 PE=1 SV=2 3.91 2773.6 - 641105 - - - 1.0474 - 2.369 0.515 - 469 1 2 0 0.0015 11 0 0 0 1.25E+09 4.83E+08 - - - 5.1775 0.9994 221125_WJC_METTL3_EV_vs_WT_F04.15403.15403.3 3.63E-05 Nov-36 R.TKDIEDVFYK.Y "sp|Q07955|SRSF1_HUMAN,tr|J3QQV5|J3QQV5_HUMAN,tr|J3KTL2|J3KTL2_HUMAN,tr|J3KSW7|J3KSW7_HUMAN" 4 1256.6289 1.16 49203 15403 3 1256.632223 419.8836 Serine\arginine-rich splicing factor 1 OS=Homo sapiens OX=9606 GN=SRSF1 PE=1 SV=2 4.56 2773.9 - 537468 - - - 2.669 - 2.552 0.429 - 238.5 1 2 1 0.0034 10 0 0 0 2.22E+07 1.91E+07 - - - 6.0581 0.9995 221125_WJC_METTL3_EV_vs_WT_F04.15404.15404.2 0.000112 20-Dec K.EEEWDPEYTPK[136.11].S "sp|Q9NYF8|BCLF1_HUMAN,sp|Q9Y2W1|TR150_HUMAN,tr|A0A3B3ITZ9|A0A3B3ITZ9_HUMAN,tr|H0YF14|H0YF14_HUMAN" 4 1429.6129 2.58 49204 15404 2 1429.616714 715.8137 Bcl-2-associated transcription factor 1 OS=Homo sapiens OX=9606 GN=BCLAF1 PE=1 SV=2 3.91 2774 - 456677 - - - 2.6742 - 2.101 0.51 - 489.2 1 2 0 0.0038 11 0 0 0 1.25E+09 4.83E+08 - - - 4.8151 0.9863 221125_WJC_METTL3_EV_vs_WT_F04.15406.15406.3 0.000249 Nov-40 F.GIQEHIDLGIK.Y "sp|P62913|RL11_HUMAN,tr|Q5VVC8|Q5VVC8_HUMAN" 2 1221.6717 1.09 49206 15406 3 1221.672041 408.2312 60S ribosomal protein L11 OS=Homo sapiens OX=9606 GN=RPL11 PE=1 SV=2 5.32 2774.3 - 378989 - - - 0.2488 - 1.914 0.408 - 95.4 1 1 0 0.0003 11 0 0 0 1.95E+06 1.79E+06 - - - 4.933 0.9932 221125_WJC_METTL3_EV_vs_WT_F04.15407.15407.2 0.0001 22-Nov L.DQEIIEVDPDTK.E "sp|P08708|RS17_HUMAN,tr|H3BNC9|H3BNC9_HUMAN,tr|H0YN88|H0YN88_HUMAN,tr|A0A075B716|A0A075B716_HUMAN" 4 1400.6671 2 49207 15407 2 1400.665763 701.3408 40S ribosomal protein S17 OS=Homo sapiens OX=9606 GN=RPS17 PE=1 SV=2 3.77 2774.4 - 372649 - - - -0.9581 - 2.324 0.545 - 438 1 1 0 -0.0013 12 0 0 0 4.78E+06 2.39E+06 - - - 5.2848 0.9999 221125_WJC_METTL3_EV_vs_WT_F04.15409.15409.2 7.05E-05 20-Dec R.NPEAALSPTFR[166.11].S "sp|Q86U44|MTA70_HUMAN,tr|B4E349|B4E349_HUMAN,tr|F5H6D8|F5H6D8_HUMAN,tr|B4DTN4|B4DTN4_HUMAN" 4 1211.6174 -1 49208 15409 2 1211.618278 606.816 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 6 2774.6 - 646465 - - - 0.7189 - 2.375 0.467 - 655.6 1 2 0 0.0009 11 0 0 0 0.00E+00 0.00E+00 - - - 4.83 0.8464 221125_WJC_METTL3_EV_vs_WT_F04.15410.15410.3 0.544 Aug-44 K.ALIKEYTEEIER.L "sp|P52732|KIF11_HUMAN,tr|A0A7I2YQY4|A0A7I2YQY4_HUMAN,tr|A0A7I2V3A9|A0A7I2V3A9_HUMAN,tr|A0A7I2V3V3|A0A7I2V3V3_HUMAN" 4 1492.7773 1.86 49209 15410 3 1492.779846 498.5997 Kinesin-like protein KIF11 OS=Homo sapiens OX=9606 GN=KIF11 PE=1 SV=2 4.49 2774.7 - 494514 - - - 1.6895 - 1.702 0.114 - 93.5 1 2 1 0.0025 12 0 0 0 2.93E+06 1.58E+06 - - - 1.2844 0.9997 221125_WJC_METTL3_EV_vs_WT_F04.15411.15411.2 0.00022 22-Dec K.EQALADLNSVER[166.11].S "sp|O75410|TACC1_HUMAN,tr|E7EVI4|E7EVI4_HUMAN,tr|B4E3H6|B4E3H6_HUMAN,tr|H0YAY0|H0YAY0_HUMAN,tr|H0YBT8|H0YBT8_HUMAN,tr|E7ET87|E7ET87_HUMAN" 6 1353.6764 1.36 49210 15411 2 1353.678039 677.8455 Transforming acidic coiled-coil-containing protein 1 OS=Homo sapiens OX=9606 GN=TACC1 PE=1 SV=2 4.14 2774.8 - 5.07E+06 - - - 1.227 - 2.369 0.361 - 518 1 2 0 0.0017 12 0 0 0 3.61E+07 2.66E+07 - - - 3.9761 1 221125_WJC_METTL3_EV_vs_WT_F04.15412.15412.3 4.23E-06 Dec-60 K.IFVGGIPHNC[160.03]GETELR.E "sp|Q96EP5|DAZP1_HUMAN,tr|K7EK33|K7EK33_HUMAN,tr|K7EQ55|K7EQ55_HUMAN,tr|K7EQ02|K7EQ02_HUMAN" 4 1797.8832 1.54 49211 15412 3 1797.8845 600.3017 DAZ-associated protein 1 OS=Homo sapiens OX=9606 GN=DAZAP1 PE=1 SV=1 5.4 2774.8 - 2.20E+06 - - - 0.7214 - 2.339 0.49 - 186.2 1 2 0 0.0013 16 0 0 0 1.44E+07 9.35E+06 - - - 6.1829 0.9949 221125_WJC_METTL3_EV_vs_WT_F04.15413.15413.3 0.0796 Aug-36 K.QNEEFR[166.11]PFIR[166.11].R "sp|O15258|RER1_HUMAN,tr|Q5T092|Q5T092_HUMAN,tr|Q5T091|Q5T091_HUMAN,tr|A0A0A0MR06|A0A0A0MR06_HUMAN" 4 1354.6897 1.36 49212 15413 3 1354.691471 452.5705 Protein RER1 OS=Homo sapiens OX=9606 GN=RER1 PE=1 SV=1 6.14 2774.9 - 1.20E+06 - - - 1.3265 - 1.82 0.189 - 134.8 1 2 0 0.0018 10 0 0 0 9.91E+06 7.30E+06 - - - 2.3955 0.9999 221125_WJC_METTL3_EV_vs_WT_F04.15414.15414.3 6.34E-07 14/52 R.LDHDVAAAVSGVYR[166.11].R sp|Q6QNY0|BL1S3_HUMAN 1 1481.7502 2.13 49213 15414 3 1481.752814 494.924 Biogenesis of lysosome-related organelles complex 1 subunit 3 OS=Homo sapiens OX=9606 GN=BLOC1S3 PE=1 SV=1 5.21 2774.9 - 1.14E+06 - - - 1.756 - 2.43 0.484 - 288.9 1 2 0 0.0026 14 0 0 0 2.65E+07 1.25E+07 - - - 6.295 0.9999 221125_WJC_METTL3_EV_vs_WT_F04.15416.15416.2 4.12E-11 14/24 K.NNAYLAQSPQLYK[136.11].Q sp|P14868|SYDC_HUMAN 1 1516.7765 1.1 49215 15416 2 1516.77779 759.3955 "Aspartate--tRNA ligase, cytoplasmic OS=Homo sapiens OX=9606 GN=DARS1 PE=1 SV=2" 8.5 2775.2 - 648144 - - - 0.8221 - 2.707 0.467 - 704.8 1 2 0 0.0012 13 0 0 0 5.20E+06 4.74E+06 - - - 5.0457 0.9996 221125_WJC_METTL3_EV_vs_WT_F04.15417.15417.2 0.0144 18-Sep R.DSTTDEQLFR.C "sp|Q92696|PGTA_HUMAN,tr|H0YLH3|H0YLH3_HUMAN" 2 1210.5466 -1 49216 15417 2 1210.547948 606.2806 Geranylgeranyl transferase type-2 subunit alpha OS=Homo sapiens OX=9606 GN=RABGGTA PE=1 SV=2 4.03 2775.3 - 646465 - - - 1.1169 - 1.941 0.38 - 402.3 1 2 0 0.0014 10 0 0 0 0.00E+00 0.00E+00 - - - 3.6985 1 221125_WJC_METTL3_EV_vs_WT_F04.15418.15418.2 1.27E-07 15/28 K.C[160.03]IVNNVSAETVQTVR.Y sp|Q8N0X7|SPART_HUMAN 1 1688.8516 0.7 49217 15418 2 1688.864688 845.4331 Spartin OS=Homo sapiens OX=9606 GN=SPART PE=1 SV=1 5.99 2775.5 - 581167 - - - 7.768 - 3.135 0.627 - 509.1 1 2 0 0.0131 15 0 0 0 5.18E+06 7.35E+06 - - - 6.4771 1 221125_WJC_METTL3_EV_vs_WT_F04.15421.15421.3 2.13E-06 25/68 K.LPGGELNPGEDEVEGLK[136.11]R[166.11].L "sp|O43809|CPSF5_HUMAN,tr|H3BV41|H3BV41_HUMAN,tr|H3BND3|H3BND3_HUMAN" 3 1925.9813 1.18 49220 15421 3 1925.981515 643.0011 Cleavage and polyadenylation specificity factor subunit 5 OS=Homo sapiens OX=9606 GN=NUDT21 PE=1 SV=1 4.25 2775.9 - 376757 - - - 0.0903 - 4.007 0.548 - 848.9 1 2 0 0.0002 18 0 0 0 1.06E+07 8.92E+06 - - - 8.106 0.9999 221125_WJC_METTL3_EV_vs_WT_F04.15422.15422.2 1.22E-07 13/28 K.IQQLTALGAAQATAK.A "sp|Q99471|PFD5_HUMAN,tr|H3BMQ1|H3BMQ1_HUMAN,tr|H3BPF6|H3BPF6_HUMAN,tr|F8VNW6|F8VNW6_HUMAN,tr|A0A0D9SFR8|A0A0D9SFR8_HUMAN" 5 1483.8358 -1 49221 15422 2 1483.836277 742.9252 Prefoldin subunit 5 OS=Homo sapiens OX=9606 GN=PFDN5 PE=1 SV=2 8.75 2776 - 367293 - - - 0.2932 - 2.682 0.566 - 606.8 1 2 0 0.0004 15 0 0 0 0.00E+00 0.00E+00 - - - 5.6468 0.9999 221125_WJC_METTL3_EV_vs_WT_F04.15423.15423.2 1.94E-06 14/24 K.STSLASVSQLASK.S sp|Q9NXV6|CARF_HUMAN 1 1277.6827 0.27 49222 15423 2 1277.683185 639.8486 CDKN2A-interacting protein OS=Homo sapiens OX=9606 GN=CDKN2AIP PE=1 SV=3 8.47 2776.1 - 358250 - - - 0.3827 - 2.432 0.46 - 394.7 1 2 0 0.0005 13 0 0 0 4.96E+06 1.84E+07 - - - 4.7193 0.9992 221125_WJC_METTL3_EV_vs_WT_F04.15424.15424.2 0.0146 22-Oct R.SPQNQYPAELMR[166.11].R "sp|P33993|MCM7_HUMAN,tr|C9J8M6|C9J8M6_HUMAN" 2 1442.6852 0.83 49223 15424 2 1442.687886 722.3499 DNA replication licensing factor MCM7 OS=Homo sapiens OX=9606 GN=MCM7 PE=1 SV=4 5.72 2776.2 - 284788 - - - 1.8833 - 1.96 0.349 - 144.5 1 2 0 0.0027 12 0 0 0 1.22E+06 1.47E+06 - - - 3.3885 0.9999 221125_WJC_METTL3_EV_vs_WT_F04.15428.15428.3 0.0271 14/52 K.AQIHDLVLVGGSTR[166.11].L "sp|P0DMV8|HS71A_HUMAN,sp|P0DMV9|HS71B_HUMAN,tr|V9GZ37|V9GZ37_HUMAN,tr|A0A0G2JIW1|A0A0G2JIW1_HUMAN" 4 1474.8131 0.34 49226 15428 3 1474.815396 492.6117 Heat shock 70 kDa protein 1A OS=Homo sapiens OX=9606 GN=HSPA1A PE=1 SV=1 6.79 2776.8 - 1.28E+07 - - - 1.5256 - 2.694 0.405 - 252.7 1 2 0 0.0022 14 0 0 0 6.38E+07 1.86E+08 - - - 5.6884 1 221125_WJC_METTL3_EV_vs_WT_F04.15430.15430.3 3.60E-07 15/52 K.LAQANGWGVMVSHR[166.11].S "sp|P06733|ENOA_HUMAN,tr|A0A2R8Y6G6|A0A2R8Y6G6_HUMAN" 2 1534.7702 1.39 49228 15430 3 1534.771883 512.5974 Alpha-enolase OS=Homo sapiens OX=9606 GN=ENO1 PE=1 SV=2 9.76 2776.9 - 3.29E+06 - - - 1.0731 - 2.918 0.503 - 389 1 2 0 0.0016 14 0 0 0 5.74E+07 4.13E+07 - - - 6.9934 0.9991 221125_WJC_METTL3_EV_vs_WT_F04.15432.15432.3 0.00429 14/68 K.LAEIGAPIQGNREELVER.L "sp|Q13435|SF3B2_HUMAN,tr|E9PPJ0|E9PPJ0_HUMAN,tr|H0YCG1|H0YCG1_HUMAN,tr|E9PJ04|E9PJ04_HUMAN,tr|E9PJT3|E9PJT3_HUMAN" 5 1993.0593 1.17 49230 15432 3 1993.059578 665.3604 Splicing factor 3B subunit 2 OS=Homo sapiens OX=9606 GN=SF3B2 PE=1 SV=2 4.49 2777 - 2.22E+06 - - - 0.1631 - 2.647 0.323 - 205 1 2 1 0.0003 18 0 0 0 4.60E+07 3.94E+07 - - - 4.565 0.9146 221125_WJC_METTL3_EV_vs_WT_F04.15434.15434.2 0.203 26-Jul K.DATNVGDEGGFAPN.L "sp|P13929|ENOB_HUMAN,sp|P06733|ENOA_HUMAN,sp|P09104|ENOG_HUMAN,tr|A0A2R8Y6G6|A0A2R8Y6G6_HUMAN,tr|E5RGZ4|E5RGZ4_HUMAN" 5 1362.5688 - 49232 15434 2 1362.568751 682.2917 Beta-enolase OS=Homo sapiens OX=9606 GN=ENO3 PE=1 SV=5 3.49 2777.1 - 1.46E+06 - - - -0.0272 - 1.032 0.389 - 73.4 1 1 0 0 14 0 0 0 - - - - - 1.9932 0.9979 221125_WJC_METTL3_EV_vs_WT_F04.15437.15437.3 0.015 Oct-52 K.MVDPEKPQLGMIDR.W "sp|P09874|PARP1_HUMAN,tr|A0A7I2V5E9|A0A7I2V5E9_HUMAN,tr|A0A7I2V625|A0A7I2V625_HUMAN,tr|A0A7I2V3E1|A0A7I2V3E1_HUMAN" 4 1627.8062 1.09 49235 15437 3 1627.808049 543.6093 Poly [ADP-ribose] polymerase 1 OS=Homo sapiens OX=9606 GN=PARP1 PE=1 SV=4 4.56 2777.3 - 802960 - - - 1.1371 - 1.762 0.258 - 107.5 1 2 0 0.0019 14 0 0 0 9.58E+06 8.77E+06 - - - 2.9213 0.9981 221125_WJC_METTL3_EV_vs_WT_F04.15439.15439.3 0.00186 Nov-36 K.SR[166.11]EWDMEALR[166.11].S sp|Q07065|CKAP4_HUMAN 1 1311.6145 12.44 49237 15439 3 1311.616303 438.2121 Cytoskeleton-associated protein 4 OS=Homo sapiens OX=9606 GN=CKAP4 PE=1 SV=2 4.68 2777.6 - 602526 - - - 1.4051 - 1.889 0.341 - 339.7 1 2 1 0.0018 10 0 0 0 2.98E+07 2.39E+06 - - - 4.1988 0.9985 221125_WJC_METTL3_EV_vs_WT_F04.15446.15446.2 6.35E-08 24-Dec K.EVESPYEVHDYIR.A "sp|Q6Y7W6|GGYF2_HUMAN,tr|A0A7I2V3H7|A0A7I2V3H7_HUMAN,tr|I1E4Y6|I1E4Y6_HUMAN,tr|A0A7I2V516|A0A7I2V516_HUMAN,tr|A0A7I2V3H0|A0A7I2V3H0_HUMAN,tr|A0A7I2V361|A0A7I2V361_HUMAN" 6 1634.7577 1.95 49244 15446 2 1634.749765 818.3861 GRB10-interacting GYF protein 2 OS=Homo sapiens OX=9606 GN=GIGYF2 PE=1 SV=1 4.4 2778.5 - 194625 - - - -4.824 - 2.593 0.542 - 492.4 1 2 0 -0.0079 13 0 0 0 2.83E+06 1.45E+06 - - - 5.4872 1 221125_WJC_METTL3_EV_vs_WT_F04.15450.15450.2 8.97E-07 17/26 K.AQIHDLVLVGGSTR[166.11].L "sp|P0DMV8|HS71A_HUMAN,sp|P0DMV9|HS71B_HUMAN,tr|V9GZ37|V9GZ37_HUMAN,tr|A0A0G2JIW1|A0A0G2JIW1_HUMAN" 4 1474.8131 0.06 49247 15450 2 1474.818586 738.4138 Heat shock 70 kDa protein 1A OS=Homo sapiens OX=9606 GN=HSPA1A PE=1 SV=1 6.79 2779 - 696014 - - - 3.6886 - 3.087 0.624 - 1014.1 1 2 0 0.0054 14 0 0 0 3.53E+05 6.26E+06 - - - 6.4768 0.9884 221125_WJC_METTL3_EV_vs_WT_F04.15451.15451.3 0.0212 16/68 K.LAEIGAPIQGNR[166.11]EELVER[166.11].L "sp|Q13435|SF3B2_HUMAN,tr|E9PPJ0|E9PPJ0_HUMAN,tr|H0YCG1|H0YCG1_HUMAN,tr|E9PJ04|E9PJ04_HUMAN,tr|E9PJT3|E9PJT3_HUMAN" 5 2013.0758 1.17 49248 15451 3 2013.076139 672.0325 Splicing factor 3B subunit 2 OS=Homo sapiens OX=9606 GN=SF3B2 PE=1 SV=2 4.49 2779 - 3.71E+06 - - - 0.1719 - 2.078 0.207 - 289.7 1 2 1 0.0003 18 0 0 0 4.60E+07 3.94E+07 - - - 2.669 0.9999 221125_WJC_METTL3_EV_vs_WT_F04.15452.15452.3 0.000135 17/52 R.ELISNSSDALDK[136.11]IR[166.11].Y "sp|P07900|HS90A_HUMAN,tr|G3V2J8|G3V2J8_HUMAN" 2 1577.838 0.64 49249 15452 3 1577.83888 526.9533 Heat shock protein HSP 90-alpha OS=Homo sapiens OX=9606 GN=HSP90AA1 PE=1 SV=5 4.56 2779.1 - 2.38E+06 - - - 0.5761 - 3.389 0.502 - 379 1 2 1 0.0009 14 0 0 0 1.73E+07 2.72E+07 - - - 7.3802 1 221125_WJC_METTL3_EV_vs_WT_F04.15453.15453.2 1.01E-07 17/30 R.GVAIGQTSLTASVTNK.A sp|Q8TEM1|PO210_HUMAN 1 1545.8362 2.83 49250 15453 2 1545.835918 773.9254 Nuclear pore membrane glycoprotein 210 OS=Homo sapiens OX=9606 GN=NUP210 PE=1 SV=3 8.75 2779.1 - 1.99E+06 - - - -0.2057 - 3.225 0.601 - 796.3 1 2 0 -0.0003 16 0 0 0 1.28E+07 4.51E+06 - - - 6.3587 0.9949 221125_WJC_METTL3_EV_vs_WT_F04.15454.15454.2 0.00842 13/18 R.TKDIEDVFYK.Y "sp|Q07955|SRSF1_HUMAN,tr|J3QQV5|J3QQV5_HUMAN,tr|J3KTL2|J3KTL2_HUMAN,tr|J3KSW7|J3KSW7_HUMAN" 4 1256.6289 1.11 49251 15454 2 1256.632581 629.3217 Serine\arginine-rich splicing factor 1 OS=Homo sapiens OX=9606 GN=SRSF1 PE=1 SV=2 4.56 2779.3 - 1.18E+06 - - - 2.9539 - 2.457 0.49 - 438.3 1 2 1 0.0037 10 0 0 0 7.20E+06 6.48E+06 - - - 5.1682 1 221125_WJC_METTL3_EV_vs_WT_F04.15455.15455.2 2.85E-09 17/30 K.VLGGNQTLTVNVEGTK.T sp|Q7Z3B4|NUP54_HUMAN 1 1628.8734 2.03 49252 15455 2 1628.875073 815.444 Nucleoporin p54 OS=Homo sapiens OX=9606 GN=NUP54 PE=1 SV=2 5.97 2779.4 - 992986 - - - 1.0578 - 3.04 0.601 - 972.6 1 2 0 0.0017 16 0 0 0 9.45E+07 4.65E+07 - - - 6.213 0.9891 221125_WJC_METTL3_EV_vs_WT_F04.15456.15456.3 9.02E-05 13/52 K.R[166.11]GLLQDDAHPTLVT.Y "sp|Q86U44|MTA70_HUMAN,tr|F5H6D8|F5H6D8_HUMAN,tr|H0YFV6|H0YFV6_HUMAN,tr|B4DTN4|B4DTN4_HUMAN" 4 1544.8186 0.01 49253 15456 3 1544.819697 515.9468 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 5.21 2779.5 - 922245 - - - 0.6933 - 2.315 0.393 - 251.5 1 1 0 0.0011 14 0 0 0 3.34E+05 2.95E+07 - - - 5.152 1 221125_WJC_METTL3_EV_vs_WT_F04.15457.15457.2 6.72E-06 16/24 R.DELADEIANSSGK.G sp|P35579|MYH9_HUMAN 1 1347.6154 1.27 49254 15457 2 1347.615018 674.815 Myosin-9 OS=Homo sapiens OX=9606 GN=MYH9 PE=1 SV=4 3.92 2779.6 - 920977 - - - -0.2864 - 2.833 0.576 - 808.4 1 2 0 -0.0004 13 0 0 0 1.84E+07 1.45E+07 - - - 5.9678 1 221125_WJC_METTL3_EV_vs_WT_F04.15458.15458.2 7.71E-09 19/30 R.GVAIGQTSLTASVTNK[136.11].A sp|Q8TEM1|PO210_HUMAN 1 1553.8504 2.8 49255 15458 2 1553.848604 777.9325 Nuclear pore membrane glycoprotein 210 OS=Homo sapiens OX=9606 GN=NUP210 PE=1 SV=3 8.75 2779.7 - 825073 - - - -1.179 - 3.099 0.579 - 996.6 1 2 0 -0.0018 16 0 0 0 1.26E+07 4.51E+06 - - - 6.0977 1 221125_WJC_METTL3_EV_vs_WT_F04.15459.15459.2 7.07E-08 18/30 K.VLGGNQTLTVNVEGTK[136.11].T sp|Q7Z3B4|NUP54_HUMAN 1 1636.8875 2.03 49256 15459 2 1636.884324 819.4511 Nucleoporin p54 OS=Homo sapiens OX=9606 GN=NUP54 PE=1 SV=2 5.97 2779.9 - 625543 - - - -1.9708 - 3.122 0.602 - 1075.5 1 2 0 -0.0032 16 0 0 0 9.36E+07 4.61E+07 - - - 6.2853 0.9999 221125_WJC_METTL3_EV_vs_WT_F04.15460.15460.3 0.00256 Sep-32 K.DYAFVHMER.A "sp|Q9BWF3|RBM4_HUMAN,sp|Q9BQ04|RBM4B_HUMAN,tr|E9PM61|E9PM61_HUMAN,tr|D6R9K7|D6R9K7_HUMAN,tr|J3QRR5|J3QRR5_HUMAN,tr|E9PB51|E9PB51_HUMAN,tr|U3KQD5|U3KQD5_HUMAN,tr|E9PLB0|E9PLB0_HUMAN" 8 1166.5179 1.45 49257 15460 3 1166.51682 389.8466 RNA-binding protein 4 OS=Homo sapiens OX=9606 GN=RBM4 PE=1 SV=1 5.32 2780 - 542453 - - - -0.9078 - 1.903 0.445 - 143.1 1 2 0 -0.0011 9 0 0 0 4.49E+07 3.10E+07 - - - 5.4402 0.9999 221125_WJC_METTL3_EV_vs_WT_F04.15461.15461.3 5.83E-05 Nov-32 K.DYAFVHMER[166.11].A "sp|Q9BWF3|RBM4_HUMAN,sp|Q9BQ04|RBM4B_HUMAN,tr|E9PM61|E9PM61_HUMAN,tr|D6R9K7|D6R9K7_HUMAN,tr|J3QRR5|J3QRR5_HUMAN,tr|E9PB51|E9PB51_HUMAN,tr|U3KQD5|U3KQD5_HUMAN,tr|E9PLB0|E9PLB0_HUMAN" 8 1176.5261 1.45 49258 15461 3 1176.526384 393.1827 RNA-binding protein 4 OS=Homo sapiens OX=9606 GN=RBM4 PE=1 SV=1 5.32 2780.1 - 530234 - - - 0.1997 - 2.05 0.461 - 267.8 1 2 0 0.0002 9 0 0 0 4.49E+07 3.10E+07 - - - 5.8431 0.9998 221125_WJC_METTL3_EV_vs_WT_F04.15468.15468.2 3.59E-06 26-Nov R.LDHDVAAAVSGVYR[166.11].R sp|Q6QNY0|BL1S3_HUMAN 1 1481.7502 1.3 49264 15468 2 1481.751939 741.8824 Biogenesis of lysosome-related organelles complex 1 subunit 3 OS=Homo sapiens OX=9606 GN=BLOC1S3 PE=1 SV=1 5.21 2781.1 - 309534 - - - 1.1655 - 2.336 0.431 - 280.1 1 2 0 0.0017 14 0 0 0 2.57E+06 1.98E+06 - - - 4.3529 0.9999 221125_WJC_METTL3_EV_vs_WT_F04.15470.15470.3 3.15E-06 18/52 R.ELISNSSDALDKIR.Y "sp|P07900|HS90A_HUMAN,tr|G3V2J8|G3V2J8_HUMAN" 2 1559.8155 0.64 49265 15470 3 1559.816691 520.9458 Heat shock protein HSP 90-alpha OS=Homo sapiens OX=9606 GN=HSP90AA1 PE=1 SV=5 4.56 2781.3 - 2.82E+06 - - - 0.7629 - 3.696 0.5 - 596.7 1 2 1 0.0012 14 0 0 0 1.74E+07 2.72E+07 - - - 7.5882 1 221125_WJC_METTL3_EV_vs_WT_F04.15471.15471.3 5.13E-05 14/44 K.LSDFGLC[160.03]TGLK[136.11]K[136.11].A "sp|Q9Y2H1|ST38L_HUMAN,sp|Q15208|STK38_HUMAN,tr|F5H277|F5H277_HUMAN,tr|H0YGN4|H0YGN4_HUMAN" 4 1353.7297 3.24 49266 15471 3 1353.728536 452.2505 Serine\threonine-protein kinase 38-like OS=Homo sapiens OX=9606 GN=STK38L PE=1 SV=3 8.2 2781.4 - 2.31E+06 - - - -0.8768 - 2.646 0.47 - 210.1 1 2 0 -0.0012 12 0 0 0 1.12E+08 3.47E+07 - - - 6.4769 0.9999 221125_WJC_METTL3_EV_vs_WT_F04.15472.15472.3 0.00294 Aug-36 R.THFDYQFGYR[166.11].K "sp|Q6PKG0|LARP1_HUMAN,tr|A0A0B4J210|A0A0B4J210_HUMAN,tr|E5RH50|E5RH50_HUMAN" 3 1342.597 1.25 49267 15472 3 1342.598387 448.5396 La-related protein 1 OS=Homo sapiens OX=9606 GN=LARP1 PE=1 SV=2 6.41 2781.5 - 2.17E+06 - - - 1.0286 - 1.537 0.476 - 123.5 1 2 0 0.0014 10 0 0 0 1.51E+07 1.20E+07 - - - 5.1018 0.9998 221125_WJC_METTL3_EV_vs_WT_F04.15474.15474.2 0.0079 24-Nov K.AVQGFFTSNNATR.D sp|O43242|PSMD3_HUMAN 1 1411.6844 27.28 49269 15474 2 1411.684611 706.8495 26S proteasome non-ATPase regulatory subunit 3 OS=Homo sapiens OX=9606 GN=PSMD3 PE=1 SV=2 9.79 2781.7 - 667835 - - - 0.1303 - 2.285 0.369 - 437 1 2 0 0.0002 13 0 0 0 8.65E+06 3.17E+05 - - - 3.8873 0.9999 221125_WJC_METTL3_EV_vs_WT_F04.15475.15475.2 0.0051 13/20 R.ALHFAISEYNK.A "sp|P01037|CYTN_HUMAN,sp|P01036|CYTS_HUMAN" 2 1291.6561 14.11 49270 15475 2 1291.655792 646.8353 Cystatin-SN OS=Homo sapiens OX=9606 GN=CST1 PE=1 SV=3 6.79 2781.9 - 654407 - - - -0.2284 - 2.577 0.484 - 643 1 2 0 -0.0003 11 0 0 0 8.14E+06 5.77E+05 - - - 5.1766 1 221125_WJC_METTL3_EV_vs_WT_F04.15476.15476.3 5.89E-05 17/48 K.VQHITDATLAIVK.G "sp|Q53H12|AGK_HUMAN,tr|E9PC15|E9PC15_HUMAN,tr|A0A3B3ITV0|A0A3B3ITV0_HUMAN,tr|A0A3B3ITX7|A0A3B3ITX7_HUMAN,tr|E9PG39|E9PG39_HUMAN,tr|A0A3B3ITD0|A0A3B3ITD0_HUMAN,tr|A0A3B3IUC9|A0A3B3IUC9_HUMAN,tr|A0A3B3ISY9|A0A3B3ISY9_HUMAN,tr|A0A3B3ISZ0|A0A3B3ISZ0_HUMAN" 9 1407.8086 1.14 49271 15476 3 1407.809438 470.2768 "Acylglycerol kinase, mitochondrial OS=Homo sapiens OX=9606 GN=AGK PE=1 SV=2" 6.71 2782 - 620243 - - - 0.6201 - 3.156 0.52 - 495.3 1 2 0 0.0009 13 0 0 0 3.24E+07 2.85E+07 - - - 7.4533 0.9992 221125_WJC_METTL3_EV_vs_WT_F04.15477.15477.3 0.0292 Nov-40 R.DLLHPSLEEEK[136.11].K "sp|Q71UM5|RS27L_HUMAN,tr|H0YMV8|H0YMV8_HUMAN,tr|C9JLI6|C9JLI6_HUMAN" 3 1316.6703 0.65 49272 15477 3 1316.670272 439.8974 40S ribosomal protein S27-like OS=Homo sapiens OX=9606 GN=RPS27L PE=1 SV=3 4.4 2782.1 - 616604 - - - -0.0562 - 1.911 0.281 - 125.9 1 2 0 -0.0001 11 0 0 0 2.53E+07 3.92E+07 - - - 3.5126 1 221125_WJC_METTL3_EV_vs_WT_F04.15479.15479.2 7.87E-07 16-Oct K.DYAFVHMER.A "sp|Q9BWF3|RBM4_HUMAN,sp|Q9BQ04|RBM4B_HUMAN,tr|E9PM61|E9PM61_HUMAN,tr|D6R9K7|D6R9K7_HUMAN,tr|J3QRR5|J3QRR5_HUMAN,tr|E9PB51|E9PB51_HUMAN,tr|U3KQD5|U3KQD5_HUMAN,tr|E9PLB0|E9PLB0_HUMAN" 8 1166.5179 1.56 49274 15479 2 1166.520499 584.2662 RNA-binding protein 4 OS=Homo sapiens OX=9606 GN=RBM4 PE=1 SV=1 5.32 2782.4 - 443091 - - - 2.246 - 2.03 0.659 - 478.6 1 2 0 0.0026 9 0 0 0 8.47E+06 5.44E+06 - - - 5.9559 0.9998 221125_WJC_METTL3_EV_vs_WT_F04.15480.15480.2 0.000394 26-Oct R.NDLSPTTVMSEGAR[166.11].N "sp|P30043|BLVRB_HUMAN,tr|A0A2R8Y7Y9|A0A2R8Y7Y9_HUMAN,tr|M0R192|M0R192_HUMAN,tr|M0QZL1|M0QZL1_HUMAN" 4 1486.6961 1.23 49275 15480 2 1486.697545 744.3553 Flavin reductase (NADPH) OS=Homo sapiens OX=9606 GN=BLVRB PE=1 SV=3 4.37 2782.5 - 342436 - - - 0.9538 - 2.227 0.493 - 284.4 1 2 0 0.0014 14 0 0 0 1.62E+07 1.32E+07 - - - 4.6911 0.998 221125_WJC_METTL3_EV_vs_WT_F04.15482.15482.2 0.000619 Jul-34 K.EITGIGPSTTTETETIAK.Y "sp|O75436|VP26A_HUMAN,tr|S4R3Q6|S4R3Q6_HUMAN" 2 1847.9364 -1 49277 15482 2 1847.930068 924.9755 Vacuolar protein sorting-associated protein 26A OS=Homo sapiens OX=9606 GN=VPS26A PE=1 SV=2 4.25 2782.8 - 0 - - - -3.4287 - 1.558 0.455 - 79.5 1 2 0 -0.0063 18 0 0 0 0.00E+00 0.00E+00 - - - 3.4898 1 221125_WJC_METTL3_EV_vs_WT_F04.15484.15484.3 5.87E-05 19/52 R.LPTSALVNLSHGSR.S "sp|Q8IZH2|XRN1_HUMAN,tr|H7C5E4|H7C5E4_HUMAN" 2 1450.7892 1.16 49278 15484 3 1450.790507 484.6037 5'-3' exoribonuclease 1 OS=Homo sapiens OX=9606 GN=XRN1 PE=1 SV=1 9.76 2783 - 1.81E+06 - - - 0.883 - 3.835 0.486 - 738.5 1 2 0 0.0013 14 0 0 0 5.17E+07 4.47E+07 - - - 7.5302 0.9995 221125_WJC_METTL3_EV_vs_WT_F04.15485.15485.2 0.0717 22-Sep K.AEGPEVDVNLPK.A "sp|Q09666|AHNK_HUMAN,sp|Q09666|AHNK_HUMAN,sp|Q09666|AHNK_HUMAN,sp|Q09666|AHNK_HUMAN,sp|Q09666|AHNK_HUMAN" 5 1266.6456 1.14 49279 15485 2 1266.645976 634.3301 Neuroblast differentiation-associated protein AHNAK OS=Homo sapiens OX=9606 GN=AHNAK PE=1 SV=2 4.14 2783.1 - 526256 - - - 0.3111 - 1.97 0.297 - 257 1 2 0 0.0004 12 0 0 0 6.07E+06 5.33E+06 - - - 3.0185 0.9975 221125_WJC_METTL3_EV_vs_WT_F04.15486.15486.2 7.02E-05 22-Oct K.DTPLSLAC[160.03]SGGR.Q "sp|O75179|ANR17_HUMAN,sp|Q8IWZ3|ANKH1_HUMAN,tr|E9PDP5|E9PDP5_HUMAN,tr|H0YM23|H0YM23_HUMAN,tr|H3BLS9|H3BLS9_HUMAN,tr|H0YLQ3|H0YLQ3_HUMAN,tr|H7C2F5|H7C2F5_HUMAN" 7 1232.5819 1.76 49280 15486 2 1232.575825 617.2982 Ankyrin repeat domain-containing protein 17 OS=Homo sapiens OX=9606 GN=ANKRD17 PE=1 SV=3 5.83 2783.2 - 2.03E+06 - - - -4.9579 - 1.803 0.557 - 244.8 1 2 0 -0.0061 12 0 0 0 2.57E+07 1.46E+07 - - - 4.704 0.9999 221125_WJC_METTL3_EV_vs_WT_F04.15487.15487.2 6.21E-05 24-Dec R.DELADEIANSSGK[136.11].G sp|P35579|MYH9_HUMAN 1 1355.6296 1.27 49281 15487 2 1355.628828 678.8221 Myosin-9 OS=Homo sapiens OX=9606 GN=MYH9 PE=1 SV=4 3.92 2783.3 - 1.73E+06 - - - -0.5724 - 2.612 0.57 - 392.9 1 2 0 -0.0008 13 0 0 0 1.84E+07 1.45E+07 - - - 5.7149 1 221125_WJC_METTL3_EV_vs_WT_F04.15488.15488.3 5.99E-08 25/52 R.LPTSALVNLSHGSR[166.11].S "sp|Q8IZH2|XRN1_HUMAN,tr|H7C5E4|H7C5E4_HUMAN" 2 1460.7975 1.28 49282 15488 3 1460.802431 487.9398 5'-3' exoribonuclease 1 OS=Homo sapiens OX=9606 GN=XRN1 PE=1 SV=1 9.76 2783.3 - 1.59E+06 - - - 3.3783 - 3.866 0.587 - 1481.9 1 2 0 0.0049 14 0 0 0 5.09E+07 3.98E+07 - - - 8.6767 1 221125_WJC_METTL3_EV_vs_WT_F04.15489.15489.3 5.25E-11 28/68 K.LPGGELNPGEDEVEGLKR.L "sp|O43809|CPSF5_HUMAN,tr|H3BV41|H3BV41_HUMAN,tr|H3BND3|H3BND3_HUMAN" 3 1907.9589 1.18 49283 15489 3 1907.964825 636.9936 Cleavage and polyadenylation specificity factor subunit 5 OS=Homo sapiens OX=9606 GN=NUDT21 PE=1 SV=1 4.25 2783.4 - 1.48E+06 - - - 3.1206 - 4.376 0.641 - 1318.7 1 2 0 0.006 18 0 0 0 1.06E+07 8.92E+06 - - - 9.3606 0.9996 221125_WJC_METTL3_EV_vs_WT_F04.15491.15491.2 0.0161 14-Oct K.DLQNFLKK.E sp|P06702|S10A9_HUMAN 1 1004.5655 999 49285 15491 2 1004.565502 503.29 Protein S100-A9 OS=Homo sapiens OX=9606 GN=S100A9 PE=1 SV=1 8.59 2783.6 - 1.39E+06 - - - 0.0209 - 1.865 0.32 - 303 1 2 0 0 8 0 0 0 3.09E+07 0.00E+00 - - - 3.2842 0.9988 221125_WJC_METTL3_EV_vs_WT_F04.15493.15493.3 2.59E-10 18/60 Y.SALILHDDEVTVTEDK.L sp|P05386|RLA1_HUMAN 1 1783.884 1.5 49287 15493 3 1783.885998 595.6353 60S acidic ribosomal protein P1 OS=Homo sapiens OX=9606 GN=RPLP1 PE=1 SV=1 4.1 2783.8 - 1.30E+06 - - - 1.1346 - 3.331 0.601 - 444.8 1 1 0 0.002 16 0 0 0 3.42E+07 2.28E+07 - - - 8.3274 0.9987 221125_WJC_METTL3_EV_vs_WT_F04.15494.15494.2 2.94E-06 22-Nov K.DTPLSLAC[160.03]SGGR[166.11].Q "sp|O75179|ANR17_HUMAN,sp|Q8IWZ3|ANKH1_HUMAN,tr|E9PDP5|E9PDP5_HUMAN,tr|H0YM23|H0YM23_HUMAN,tr|H3BLS9|H3BLS9_HUMAN,tr|H0YLQ3|H0YLQ3_HUMAN,tr|H7C2F5|H7C2F5_HUMAN" 7 1242.5902 1.76 49288 15494 2 1242.584829 622.3024 Ankyrin repeat domain-containing protein 17 OS=Homo sapiens OX=9606 GN=ANKRD17 PE=1 SV=3 5.83 2783.8 - 1.23E+06 - - - -4.3273 - 2.035 0.569 - 405 1 2 0 -0.0054 12 0 0 0 2.57E+07 1.46E+07 - - - 5.1114 0.999 221125_WJC_METTL3_EV_vs_WT_F04.15498.15498.3 0.00526 Oct-40 R.DLLHPSLEEEK.K "sp|Q71UM5|RS27L_HUMAN,tr|H0YMV8|H0YMV8_HUMAN,tr|C9JLI6|C9JLI6_HUMAN" 3 1308.6561 0.65 49292 15498 3 1308.65514 437.226 40S ribosomal protein S27-like OS=Homo sapiens OX=9606 GN=RPS27L PE=1 SV=3 4.4 2784.3 - 617233 - - - -0.7687 - 1.719 0.289 - 90.7 1 2 0 -0.001 11 0 0 0 2.55E+07 3.95E+07 - - - 3.3008 0.9993 221125_WJC_METTL3_EV_vs_WT_F04.15499.15499.3 7.58E-05 16/60 K.ILDSVGIEADDDRLNK.V sp|P05387|RLA2_HUMAN 1 1771.8952 15.39 49293 15499 3 1771.890162 591.639 60S acidic ribosomal protein P2 OS=Homo sapiens OX=9606 GN=RPLP2 PE=1 SV=1 4.04 2784.4 - 562385 - - - -2.8478 - 2.516 0.464 - 211 1 2 1 -0.005 16 0 0 0 3.28E+06 2.13E+05 - - - 6.0792 1 221125_WJC_METTL3_EV_vs_WT_F04.15503.15503.2 6.13E-08 18-Oct K.DYDSTC[160.03]VFC[160.03]R.L sp|Q9NQE9|HINT3_HUMAN 1 1321.5067 0.44 49297 15503 2 1321.506707 661.7606 Adenosine 5'-monophosphoramidase HINT3 OS=Homo sapiens OX=9606 GN=HINT3 PE=1 SV=1 4.21 2785 - 271020 - - - -0.0114 - 2.218 0.695 - 358.6 1 2 0 0 10 0 0 0 2.32E+06 5.33E+06 - - - 6.3978 0.9999 221125_WJC_METTL3_EV_vs_WT_F04.15505.15505.2 9.04E-05 13/20 R.TAAENDFVTLK.K sp|P35908|K22E_HUMAN 1 1207.6085 14.46 49298 15505 2 1207.608451 604.8115 "Keratin, type II cytoskeletal 2 epidermal OS=Homo sapiens OX=9606 GN=KRT2 PE=1 SV=2" 4.37 2785.2 - 3.96E+06 - - - -0.0141 - 2.51 0.42 - 521.4 1 2 0 0 11 0 0 0 4.37E+07 3.02E+06 - - - 4.6327 0.9543 221125_WJC_METTL3_EV_vs_WT_F04.15506.15506.2 0.00543 24-Oct K.EQEELNDAVGFSR[166.11].V "sp|O95453|PARN_HUMAN,tr|A0A494C0Q6|A0A494C0Q6_HUMAN,tr|A0A494BZW7|A0A494BZW7_HUMAN,tr|A0A494C0Q2|A0A494C0Q2_HUMAN,tr|A0A494BZU6|A0A494BZU6_HUMAN,tr|A0A494C1G3|A0A494C1G3_HUMAN,tr|A0A494C002|A0A494C002_HUMAN,tr|A0A494C1K5|A0A494C1K5_HUMAN,tr|A0A494C156|A0A494C156_HUMAN,tr|A0A494C1N1|A0A494C1N1_HUMAN,tr|A0A494C0W0|A0A494C0W0_HUMAN,tr|A0A494C0P9|A0A494C0P9_HUMAN,tr|A0A494C0K5|A0A494C0K5_HUMAN" 13 1502.6877 2.71 49299 15506 2 1502.699094 752.3511 Poly(A)-specific ribonuclease PARN OS=Homo sapiens OX=9606 GN=PARN PE=1 SV=1 4 2785.3 - 1.21E+06 - - - 7.6017 - 1.813 0.328 - 225.1 1 2 0 0.0114 13 0 0 0 2.32E+07 8.58E+06 - - - 2.9871 1 221125_WJC_METTL3_EV_vs_WT_F04.15507.15507.3 3.50E-08 16/48 K.VQHITDATLAIVK[136.11].G "sp|Q53H12|AGK_HUMAN,tr|E9PC15|E9PC15_HUMAN,tr|A0A3B3ITV0|A0A3B3ITV0_HUMAN,tr|A0A3B3ITX7|A0A3B3ITX7_HUMAN,tr|E9PG39|E9PG39_HUMAN,tr|A0A3B3ITD0|A0A3B3ITD0_HUMAN,tr|A0A3B3IUC9|A0A3B3IUC9_HUMAN,tr|A0A3B3ISY9|A0A3B3ISY9_HUMAN,tr|A0A3B3ISZ0|A0A3B3ISZ0_HUMAN" 9 1415.8228 1.15 49300 15507 3 1415.822397 472.9482 "Acylglycerol kinase, mitochondrial OS=Homo sapiens OX=9606 GN=AGK PE=1 SV=2" 6.71 2785.3 - 2.62E+06 - - - -0.2599 - 2.932 0.57 - 482.8 1 2 0 -0.0004 13 0 0 0 3.26E+07 2.85E+07 - - - 7.8113 0.9999 221125_WJC_METTL3_EV_vs_WT_F04.15508.15508.2 0.000243 18-Nov K.SQAFIEMETR[166.11].E "sp|P43243|MATR3_HUMAN,tr|B3KM87|B3KM87_HUMAN,tr|A8MXP9|A8MXP9_HUMAN,tr|A0A0R4J2E8|A0A0R4J2E8_HUMAN,tr|H0Y8T4|H0Y8T4_HUMAN,tr|D6REM6|D6REM6_HUMAN" 6 1220.5735 0.25 49301 15508 2 1220.572514 611.294 Matrin-3 OS=Homo sapiens OX=9606 GN=MATR3 PE=1 SV=2 4.53 2785.4 - 2.37E+06 - - - -0.8021 - 2.148 0.499 - 541.6 1 2 0 -0.001 10 0 0 0 5.32E+07 2.16E+08 - - - 4.8604 0.9999 221125_WJC_METTL3_EV_vs_WT_F04.15509.15509.3 4.84E-05 14/40 R.QSVEADINGLR.R "sp|P13645|K1C10_HUMAN,sp|Q2M2I5|K1C24_HUMAN,sp|Q7Z3Y8|K1C27_HUMAN,sp|P13646|K1C13_HUMAN,tr|A0A1B0GVI3|A0A1B0GVI3_HUMAN,tr|K7EMD9|K7EMD9_HUMAN,tr|K7ERE3|K7ERE3_HUMAN" 7 1200.6099 487.98 49302 15509 3 1200.609804 401.2106 "Keratin, type I cytoskeletal 10 OS=Homo sapiens OX=9606 GN=KRT10 PE=1 SV=6" 4.37 2785.5 - 1.11E+06 - - - -0.0508 - 2.088 0.423 - 235.3 1 2 0 -0.0001 11 0 0 0 1.34E+08 2.74E+05 - - - 5.3475 0.9999 221125_WJC_METTL3_EV_vs_WT_F04.15510.15510.3 1.76E-05 Nov-40 K.EEEWDPEYTPK[136.11].S "sp|Q9NYF8|BCLF1_HUMAN,sp|Q9Y2W1|TR150_HUMAN,tr|A0A3B3ITZ9|A0A3B3ITZ9_HUMAN,tr|H0YF14|H0YF14_HUMAN" 4 1429.6129 4.53 49303 15510 3 1429.609572 477.5449 Bcl-2-associated transcription factor 1 OS=Homo sapiens OX=9606 GN=BCLAF1 PE=1 SV=2 3.91 2785.6 - 647634 - - - -2.3216 - 1.952 0.497 - 184.6 1 2 0 -0.0033 11 0 0 0 1.84E+07 4.06E+06 - - - 5.9802 0.9999 221125_WJC_METTL3_EV_vs_WT_F04.15511.15511.3 9.15E-05 Dec-40 R.KLGINSLQELK.Q "sp|P55327|TPD52_HUMAN,tr|H0YC44|H0YC44_HUMAN,tr|E5RFR7|E5RFR7_HUMAN,tr|H0YC42|H0YC42_HUMAN" 4 1241.7343 2.29 49304 15511 3 1241.731429 414.9187 Tumor protein D52 OS=Homo sapiens OX=9606 GN=TPD52 PE=1 SV=2 8.59 2785.7 - 496066 - - - -2.3419 - 2.31 0.437 - 192.1 1 2 0 -0.0029 11 0 0 0 6.54E+06 2.86E+06 - - - 5.7898 1 221125_WJC_METTL3_EV_vs_WT_F04.15512.15512.2 2.11E-06 15/30 R.C[160.03]VIC[160.03]GGPGVSDAYYC[160.03]K.E sp|Q7RTV0|PHF5A_HUMAN 1 1804.7583 1.44 49305 15512 2 1804.75877 903.3864 PHD finger-like domain-containing protein 5A OS=Homo sapiens OX=9606 GN=PHF5A PE=1 SV=1 5.81 2785.9 - 460138 - - - 0.2809 - 3.158 0.675 - 537.3 1 2 0 0.0005 16 0 0 0 1.52E+07 1.05E+07 - - - 6.8536 0.9978 221125_WJC_METTL3_EV_vs_WT_F04.15513.15513.2 9.90E-05 20-Nov R.DLLHPSLEEEK[136.11].K "sp|Q71UM5|RS27L_HUMAN,tr|H0YMV8|H0YMV8_HUMAN,tr|C9JLI6|C9JLI6_HUMAN" 3 1316.6703 0.31 49306 15513 2 1316.668021 659.3424 40S ribosomal protein S27-like OS=Homo sapiens OX=9606 GN=RPS27L PE=1 SV=3 4.4 2786 - 369476 - - - -1.7658 - 2.194 0.141 - 274.7 1 2 0 -0.0023 11 0 0 0 3.80E+06 1.23E+07 - - - 2.2073 1 221125_WJC_METTL3_EV_vs_WT_F04.15518.15518.3 3.42E-07 19/60 Y.SALILHDDEVTVTEDK[136.11].L sp|P05386|RLA1_HUMAN 1 1791.8982 1.5 49309 15518 3 1791.899282 598.3067 60S acidic ribosomal protein P1 OS=Homo sapiens OX=9606 GN=RPLP1 PE=1 SV=1 4.1 2786.7 - 1.85E+06 - - - 0.6183 - 3.533 0.607 - 499.9 1 1 0 0.0011 16 0 0 0 3.42E+07 2.28E+07 - - - 8.5456 1 221125_WJC_METTL3_EV_vs_WT_F04.15519.15519.3 1.02E-07 16/60 K.VLGGNQTLTVNVEGTK.T sp|Q7Z3B4|NUP54_HUMAN 1 1628.8734 2.18 49310 15519 3 1628.872414 543.9651 Nucleoporin p54 OS=Homo sapiens OX=9606 GN=NUP54 PE=1 SV=2 5.97 2786.7 - 2.12E+06 - - - -0.5746 - 2.671 0.462 - 331 1 2 0 -0.0009 16 0 0 0 2.03E+07 9.28E+06 - - - 6.2114 0.9999 221125_WJC_METTL3_EV_vs_WT_F04.15522.15522.2 5.80E-05 20-Nov K.AASITSEVFNK[136.11].F sp|Q9Y5B9|SP16H_HUMAN 1 1173.6121 1.11 49313 15522 2 1173.6122 587.8133 FACT complex subunit SPT16 OS=Homo sapiens OX=9606 GN=SUPT16H PE=1 SV=1 6.05 2787 - 1.04E+06 - - - 0.0827 - 2.357 0.475 - 429.8 1 2 0 0.0001 11 0 0 0 1.34E+07 1.20E+07 - - - 4.8688 1 221125_WJC_METTL3_EV_vs_WT_F04.15524.15524.2 1.66E-07 26-Nov R.NDLSPTTVMSEGAR.N "sp|P30043|BLVRB_HUMAN,tr|A0A2R8Y7Y9|A0A2R8Y7Y9_HUMAN,tr|M0R192|M0R192_HUMAN,tr|M0QZL1|M0QZL1_HUMAN" 4 1476.6879 1.23 49315 15524 2 1476.684291 739.3512 Flavin reductase (NADPH) OS=Homo sapiens OX=9606 GN=BLVRB PE=1 SV=3 4.37 2787.2 - 696742 - - - -2.4149 - 2.532 0.599 - 306.1 1 2 0 -0.0036 14 0 0 0 1.62E+07 1.32E+07 - - - 5.7954 1 221125_WJC_METTL3_EV_vs_WT_F04.15525.15525.2 1.42E-05 14/30 R.C[160.03]VIC[160.03]GGPGVSDAYYC[160.03]K[136.11].E sp|Q7RTV0|PHF5A_HUMAN 1 1812.7725 1.44 49316 15525 2 1812.769157 907.3935 PHD finger-like domain-containing protein 5A OS=Homo sapiens OX=9606 GN=PHF5A PE=1 SV=1 5.81 2787.4 - 548921 - - - -1.8237 - 3.272 0.653 - 367.1 1 2 0 -0.0033 16 0 0 0 1.52E+07 1.05E+07 - - - 6.7774 0.9999 221125_WJC_METTL3_EV_vs_WT_F04.15534.15534.2 2.07E-06 17/18 K.KQELLEALTK.H "sp|P12956|XRCC6_HUMAN,tr|B1AHC9|B1AHC9_HUMAN" 2 1171.6812 1.18 49323 15534 2 1171.681243 586.8479 X-ray repair cross-complementing protein 6 OS=Homo sapiens OX=9606 GN=XRCC6 PE=1 SV=2 6.14 2788.5 - 1.75E+06 - - - 0.0034 - 3.081 0.428 - 1061.8 1 2 0 0 10 0 0 0 2.57E+07 2.17E+07 - - - 5.3431 0.9998 221125_WJC_METTL3_EV_vs_WT_F04.15535.15535.3 7.54E-06 14/44 R.LK[136.11]LEPHEGLLLR[166.11].F "sp|P08195|4F2_HUMAN,tr|A0A7P0TAN7|A0A7P0TAN7_HUMAN,tr|J3KPF3|J3KPF3_HUMAN,tr|F5H056|F5H056_HUMAN,tr|F5GZI0|F5GZI0_HUMAN,tr|A0A7P0T9F7|A0A7P0T9F7_HUMAN,tr|A0A7P0TBF8|A0A7P0TBF8_HUMAN,tr|A0A7P0Z4A0|A0A7P0Z4A0_HUMAN,tr|F5GZS6|F5GZS6_HUMAN,tr|A0A7P0Z4P5|A0A7P0Z4P5_HUMAN" 10 1434.8678 1.02 49324 15535 3 1434.866552 479.2965 4F2 cell-surface antigen heavy chain OS=Homo sapiens OX=9606 GN=SLC3A2 PE=1 SV=3 6.76 2788.6 - 1.55E+06 - - - -0.8384 - 2.322 0.489 - 193.1 1 2 1 -0.0012 12 0 0 0 1.93E+07 1.90E+07 - - - 6.3266 0.9999 221125_WJC_METTL3_EV_vs_WT_F04.15536.15536.2 9.29E-07 20-Nov K.AASITSEVFNK.F sp|Q9Y5B9|SP16H_HUMAN 1 1165.5979 1.11 49325 15536 2 1165.598267 583.8062 FACT complex subunit SPT16 OS=Homo sapiens OX=9606 GN=SUPT16H PE=1 SV=1 6.05 2788.7 - 1.30E+06 - - - 0.3123 - 2.301 0.515 - 479.9 1 2 0 0.0004 11 0 0 0 1.34E+07 1.20E+07 - - - 5.0991 0.9997 221125_WJC_METTL3_EV_vs_WT_F04.15538.15538.3 7.19E-05 Nov-48 K.FQSPYEEQLEQQR.L "sp|O00461|GOLI4_HUMAN,tr|F8W785|F8W785_HUMAN" 2 1680.7744 2.02 49327 15538 3 1680.775107 561.2654 Golgi integral membrane protein 4 OS=Homo sapiens OX=9606 GN=GOLIM4 PE=1 SV=1 4.25 2788.9 - 746324 - - - 0.4421 - 1.912 0.358 - 132 1 2 0 0.0007 13 0 0 0 1.74E+07 8.60E+06 - - - 4.2885 1 221125_WJC_METTL3_EV_vs_WT_F04.15539.15539.2 2.76E-07 17/38 K.GLGGSGGAGGPPGTPYELAK.E sp|Q9ULL5|PRR12_HUMAN 1 1741.8635 3.07 49328 15539 2 1741.862579 871.939 Proline-rich protein 12 OS=Homo sapiens OX=9606 GN=PRR12 PE=1 SV=3 6 2789.1 - 739274 - - - -0.5368 - 3.304 0.602 - 636.8 1 2 0 -0.0009 20 0 0 0 1.13E+07 3.68E+06 - - - 6.4254 0.9977 221125_WJC_METTL3_EV_vs_WT_F04.15540.15540.2 0.0189 20-Aug R.DLLHPSLEEEK.K "sp|Q71UM5|RS27L_HUMAN,tr|H0YMV8|H0YMV8_HUMAN,tr|C9JLI6|C9JLI6_HUMAN" 3 1308.6561 0.31 49329 15540 2 1308.65305 655.3353 40S ribosomal protein S27-like OS=Homo sapiens OX=9606 GN=RPS27L PE=1 SV=3 4.4 2789.2 - 396829 - - - -2.3658 - 1.783 0.263 - 143.6 1 2 0 -0.0031 11 0 0 0 3.67E+06 1.19E+07 - - - 2.547 1 221125_WJC_METTL3_EV_vs_WT_F04.15541.15541.2 1.76E-10 13/26 R.LEVDEDFEEDNAAK.V sp|Q92620|PRP16_HUMAN 1 1622.6948 1.16 49330 15541 2 1622.694851 812.3547 Pre-mRNA-splicing factor ATP-dependent RNA helicase PRP16 OS=Homo sapiens OX=9606 GN=DHX38 PE=1 SV=2 3.66 2789.3 - 253920 - - - 0.0462 - 2.785 0.653 - 463.2 1 2 0 0.0001 14 0 0 0 2.85E+06 2.46E+06 - - - 6.4343 1 221125_WJC_METTL3_EV_vs_WT_F04.15545.15545.3 3.53E-06 Dec-48 K.LGITHVLNAAEGR.S "sp|P51452|DUS3_HUMAN,tr|K7ES89|K7ES89_HUMAN" 2 1349.7415 1.27 49332 15545 3 1349.742614 450.9211 Dual specificity protein phosphatase 3 OS=Homo sapiens OX=9606 GN=DUSP3 PE=1 SV=1 6.75 2789.8 - 1.49E+06 - - - 0.7898 - 2.502 0.453 - 201.4 1 2 0 0.0011 13 0 0 0 1.82E+07 1.43E+07 - - - 6.0767 0.9998 221125_WJC_METTL3_EV_vs_WT_F04.15546.15546.2 0.000224 13/26 K.SVVTGGVQSVMGSR.L "sp|O60664|PLIN3_HUMAN,tr|K7ERZ3|K7ERZ3_HUMAN,tr|K7EL96|K7EL96_HUMAN" 3 1362.6925 0.8 49333 15546 2 1362.694325 682.3536 Perilipin-3 OS=Homo sapiens OX=9606 GN=PLIN3 PE=1 SV=3 9.47 2789.9 - 943368 - - - 1.3033 - 2.327 0.504 - 539.2 1 2 0 0.0018 14 0 0 0 1.26E+07 1.58E+07 - - - 4.8824 1 221125_WJC_METTL3_EV_vs_WT_F04.15547.15547.3 4.36E-06 14/48 K.LGITHVLNAAEGR[166.11].S "sp|P51452|DUS3_HUMAN,tr|K7ES89|K7ES89_HUMAN" 2 1359.7498 1.27 49334 15547 3 1359.747646 454.2572 Dual specificity protein phosphatase 3 OS=Homo sapiens OX=9606 GN=DUSP3 PE=1 SV=1 6.75 2790 - 836517 - - - -1.5974 - 3.043 0.503 - 356.3 1 2 0 -0.0022 13 0 0 0 1.83E+07 1.44E+07 - - - 7.1646 1 221125_WJC_METTL3_EV_vs_WT_F04.15548.15548.4 9.93E-05 16/84 R.LLLEGISSTHVNHLR.C "sp|Q9NR46|SHLB2_HUMAN,tr|B7ZC39|B7ZC39_HUMAN,tr|B7ZC38|B7ZC38_HUMAN" 3 1687.937 1.53 49335 15548 4 1687.935904 422.9915 Endophilin-B2 OS=Homo sapiens OX=9606 GN=SH3GLB2 PE=1 SV=1 6.92 2790.1 - 726587 - - - -0.6215 - 3.009 0.469 - 289.8 1 2 0 -0.001 15 0 0 0 8.22E+06 5.36E+06 - - - 3.7021 0.9998 221125_WJC_METTL3_EV_vs_WT_F04.15549.15549.2 1.22E-07 26-Dec K.AGQSVIGLQMGTNK.C "sp|Q15417|CNN3_HUMAN,tr|E9PDU6|E9PDU6_HUMAN" 2 1402.7238 0.55 49336 15549 2 1402.725243 702.3692 Calponin-3 OS=Homo sapiens OX=9606 GN=CNN3 PE=1 SV=1 8.8 2790.2 - 624962 - - - 0.9938 - 2.693 0.417 - 541.2 1 2 0 0.0014 14 0 0 0 7.00E+06 1.28E+07 - - - 4.6065 0.9999 221125_WJC_METTL3_EV_vs_WT_F04.15550.15550.3 0.000189 Dec-48 K.FQSPYEEQLEQQR[166.11].L "sp|O00461|GOLI4_HUMAN,tr|F8W785|F8W785_HUMAN" 2 1690.7826 2.4 49337 15550 3 1690.784362 564.6015 Golgi integral membrane protein 4 OS=Homo sapiens OX=9606 GN=GOLIM4 PE=1 SV=1 4.25 2790.4 - 605598 - - - 1.022 - 2.397 0.429 - 222.6 1 2 0 0.0017 13 0 0 0 2.25E+07 9.36E+06 - - - 5.6927 0.9999 221125_WJC_METTL3_EV_vs_WT_F04.15551.15551.2 3.34E-05 13/24 K.LGITHVLNAAEGR.S "sp|P51452|DUS3_HUMAN,tr|K7ES89|K7ES89_HUMAN" 2 1349.7415 1.94 49338 15551 2 1349.741102 675.8781 Dual specificity protein phosphatase 3 OS=Homo sapiens OX=9606 GN=DUSP3 PE=1 SV=1 6.75 2790.5 - 523821 - - - -0.3304 - 2.664 0.475 - 559.4 1 2 0 -0.0004 13 0 0 0 5.89E+06 3.04E+06 - - - 5.064 0.9997 221125_WJC_METTL3_EV_vs_WT_F04.15552.15552.3 0.00114 Sep-36 R.R[166.11]WEEVQSYIR[166.11].K sp|Q86UP2|KTN1_HUMAN 1 1384.7002 6.26 49339 15552 3 1384.700023 462.574 Kinectin OS=Homo sapiens OX=9606 GN=KTN1 PE=1 SV=1 6.14 2790.6 - 269591 - - - -0.156 - 1.885 0.349 - 148.6 1 2 0 -0.0002 10 0 0 0 1.20E+07 1.91E+06 - - - 4.2823 0.9886 221125_WJC_METTL3_EV_vs_WT_F04.15555.15555.3 0.000145 15/44 L.RLSVEADINGLR.R "sp|Q04695|K1C17_HUMAN,tr|F5GWP8|F5GWP8_HUMAN" 2 1341.7365 64.5 49340 15555 3 1341.734879 448.2528 "Keratin, type I cytoskeletal 17 OS=Homo sapiens OX=9606 GN=KRT17 PE=1 SV=2" 6.07 2791 - 1.17E+07 - - - -1.1798 - 2.937 0.328 - 526.8 1 1 0 -0.0016 12 0 0 0 7.15E+08 1.11E+07 - - - 5.1828 0.9999 221125_WJC_METTL3_EV_vs_WT_F04.15556.15556.3 9.69E-06 Nov-44 R.EEIDHAEYYLYK[136.11].F "sp|Q92552|RT27_HUMAN,tr|G5EA06|G5EA06_HUMAN,tr|D6RH20|D6RH20_HUMAN,tr|E5RJ73|E5RJ73_HUMAN,tr|D6RJC7|D6RJC7_HUMAN" 5 1579.7286 1 49341 15556 3 1579.727113 527.5835 "28S ribosomal protein S27, mitochondrial OS=Homo sapiens OX=9606 GN=MRPS27 PE=1 SV=3" 4.4 2791.1 - 4.27E+06 - - - -0.935 - 1.987 0.475 - 124.9 1 2 0 -0.0015 12 0 0 0 4.96E+07 4.96E+07 - - - 5.7386 0.9923 221125_WJC_METTL3_EV_vs_WT_F04.15558.15558.2 0.000215 21/22 L.RLSVEADINGLR.R "sp|Q04695|K1C17_HUMAN,tr|F5GWP8|F5GWP8_HUMAN" 2 1341.7365 108.45 49343 15558 2 1341.734657 671.8755 "Keratin, type I cytoskeletal 17 OS=Homo sapiens OX=9606 GN=KRT17 PE=1 SV=2" 6.07 2791.3 - 1.77E+06 - - - -1.3453 - 3.24 0.447 - 655.2 1 1 0 -0.0018 12 0 0 0 9.79E+07 9.02E+05 - - - 5.4351 1 221125_WJC_METTL3_EV_vs_WT_F04.15559.15559.2 1.68E-10 18/34 R.GAGTGGLGLAVEGPSEAK.M "sp|P21333|FLNA_HUMAN,tr|Q60FE5|Q60FE5_HUMAN" 2 1569.7999 1.02 49344 15559 2 1569.799087 785.9072 Filamin-A OS=Homo sapiens OX=9606 GN=FLNA PE=1 SV=4 4.53 2791.4 - 955226 - - - -0.4867 - 3.455 0.616 - 984.4 1 2 0 -0.0008 18 0 0 0 2.48E+07 2.44E+07 - - - 6.6387 1 221125_WJC_METTL3_EV_vs_WT_F04.15561.15561.2 3.74E-09 16/34 R.GAGTGGLGLAVEGPSEAK[136.11].M "sp|P21333|FLNA_HUMAN,tr|Q60FE5|Q60FE5_HUMAN" 2 1577.8141 1.02 49346 15561 2 1577.816214 789.9143 Filamin-A OS=Homo sapiens OX=9606 GN=FLNA PE=1 SV=4 4.53 2791.7 - 765166 - - - 1.3709 - 3.278 0.582 - 764.4 1 2 0 0.0022 18 0 0 0 2.48E+07 2.44E+07 - - - 6.2578 0.9999 221125_WJC_METTL3_EV_vs_WT_F04.15562.15562.4 7.41E-07 17/84 R.LLLEGISSTHVNHLR[166.11].C "sp|Q9NR46|SHLB2_HUMAN,tr|B7ZC39|B7ZC39_HUMAN,tr|B7ZC38|B7ZC38_HUMAN" 3 1697.9452 1.53 49347 15562 4 1697.942871 425.4936 Endophilin-B2 OS=Homo sapiens OX=9606 GN=SH3GLB2 PE=1 SV=1 6.92 2791.8 - 755910 - - - -1.3852 - 3.099 0.385 - 288.9 1 2 0 -0.0024 15 0 0 0 8.22E+06 5.36E+06 - - - 2.9811 1 221125_WJC_METTL3_EV_vs_WT_F04.15564.15564.3 0.000143 16/52 K.FLESTDSFNNELKR.L "sp|Q969G3|SMCE1_HUMAN,tr|A0A2R8Y855|A0A2R8Y855_HUMAN,tr|A0A2R8YES3|A0A2R8YES3_HUMAN,tr|A0A2U3TZQ7|A0A2U3TZQ7_HUMAN,tr|A0A2R8Y7U4|A0A2R8Y7U4_HUMAN,tr|B4DGM3|B4DGM3_HUMAN,tr|J3QKS7|J3QKS7_HUMAN,tr|A0A2R8Y4T4|A0A2R8Y4T4_HUMAN,tr|A0A2R8Y7I9|A0A2R8Y7I9_HUMAN,tr|J3QR61|J3QR61_HUMAN,tr|A0A2R8Y765|A0A2R8Y765_HUMAN" 11 1698.8213 2.21 49349 15564 3 1698.823489 567.281 SWI\SNF-related matrix-associated actin-dependent regulator of chromatin subfamily E member 1 OS=Homo sapiens OX=9606 GN=SMARCE1 PE=1 SV=2 4.68 2792 - 687724 - - - 1.2803 - 3.468 0.552 - 225.7 1 2 0 0.0022 14 0 0 0 3.21E+07 1.45E+07 - - - 7.9985 1 221125_WJC_METTL3_EV_vs_WT_F04.15566.15566.2 1.62E-10 15/30 K.YYYAVVDC[160.03]DSPETASK[136.11].L "sp|Q9H501|ESF1_HUMAN,tr|A0A087WX71|A0A087WX71_HUMAN" 2 1874.8124 0.92 49351 15566 2 1874.814758 938.4135 ESF1 homolog OS=Homo sapiens OX=9606 GN=ESF1 PE=1 SV=1 4.03 2792.3 - 446758 - - - 1.2599 - 2.969 0.748 - 711.7 1 2 0 0.0024 16 0 0 0 5.54E+06 6.01E+06 - - - 7.2404 0.9998 221125_WJC_METTL3_EV_vs_WT_F04.15567.15567.2 3.87E-06 Oct-32 R.APQTLPSPEADALAGSK[136.11].H sp|P31274|HXC9_HUMAN 1 1659.8559 2.15 49352 15567 2 1659.853397 830.9352 Homeobox protein Hox-C9 OS=Homo sapiens OX=9606 GN=HOXC9 PE=1 SV=3 4.37 2792.4 - 444551 - - - -1.517 - 2.128 0.494 - 174.1 1 2 0 -0.0025 17 0 0 0 1.25E+07 5.84E+06 - - - 4.5455 1 221125_WJC_METTL3_EV_vs_WT_F04.15568.15568.2 2.51E-10 16/30 K.YYYAVVDC[160.03]DSPETASK.L "sp|Q9H501|ESF1_HUMAN,tr|A0A087WX71|A0A087WX71_HUMAN" 2 1866.7982 0.92 49353 15568 2 1866.796719 934.4064 ESF1 homolog OS=Homo sapiens OX=9606 GN=ESF1 PE=1 SV=1 4.03 2792.5 - 262475 - - - -0.7912 - 3.131 0.765 - 793.7 1 2 0 -0.0015 16 0 0 0 5.54E+06 6.01E+06 - - - 7.4969 1 221125_WJC_METTL3_EV_vs_WT_F04.15570.15570.2 9.56E-12 17/28 R.GPAGNWGPPGDYPDR.G sp|P48634|PRC2A_HUMAN 1 1554.6852 1.13 49354 15570 2 1554.682622 778.3499 Protein PRRC2A OS=Homo sapiens OX=9606 GN=PRRC2A PE=1 SV=3 4.21 2792.8 - 1.38E+06 - - - -1.6293 - 3.527 0.693 - 866 1 2 0 -0.0025 15 0 0 0 2.84E+07 2.52E+07 - - - 7.2576 1 221125_WJC_METTL3_EV_vs_WT_F04.15571.15571.2 0.229 13/24 K.FQSPYEEQLEQQR[166.11].L "sp|O00461|GOLI4_HUMAN,tr|F8W785|F8W785_HUMAN" 2 1690.7826 2.85 49355 15571 2 1690.77705 846.3986 Golgi integral membrane protein 4 OS=Homo sapiens OX=9606 GN=GOLIM4 PE=1 SV=1 4.25 2792.9 - 399550 - - - -3.3026 - 2.948 0.572 - 664.4 1 2 0 -0.0056 13 0 0 0 2.40E+07 8.42E+06 - - - 6.0388 1 221125_WJC_METTL3_EV_vs_WT_F04.15572.15572.3 6.25E-05 16/52 K.VEQVLSLEPQHELK.F "sp|O95292|VAPB_HUMAN,tr|E5RK64|E5RK64_HUMAN" 2 1647.8832 1.12 49356 15572 3 1647.883071 550.3017 Vesicle-associated membrane protein-associated protein B\C OS=Homo sapiens OX=9606 GN=VAPB PE=1 SV=3 4.75 2792.9 - 2.60E+06 - - - -0.0698 - 3.043 0.472 - 381.6 1 2 0 -0.0001 14 0 0 0 5.67E+07 5.05E+07 - - - 6.7597 0.9997 221125_WJC_METTL3_EV_vs_WT_F04.15574.15574.3 2.27E-07 Oct-48 K.WK[136.11]DSDEADLVLAK[136.11].E sp|Q13185|CBX3_HUMAN 1 1504.7744 1.1 49358 15574 3 1504.773082 502.5988 Chromobox protein homolog 3 OS=Homo sapiens OX=9606 GN=CBX3 PE=1 SV=4 4.23 2793.1 - 1.72E+06 - - - -0.8918 - 2.247 0.44 - 182.4 1 2 1 -0.0013 13 0 0 0 1.16E+08 1.06E+08 - - - 5.6402 1 221125_WJC_METTL3_EV_vs_WT_F04.15575.15575.2 1.01E-07 13/26 R.STSGGTAALGC[160.03]LVK.D "sp|P01860|IGHG3_HUMAN,sp|P01857|IGHG1_HUMAN,tr|A0A4W9A917|A0A4W9A917_HUMAN,tr|A0A286YES1|A0A286YES1_HUMAN,tr|A0A0A0MS08|A0A0A0MS08_HUMAN,tr|A0A0A0MS07|A0A0A0MS07_HUMAN" 6 1320.6708 62.01 49359 15575 2 1320.672327 661.3427 Immunoglobulin heavy constant gamma 3 OS=Homo sapiens OX=9606 GN=IGHG3 PE=1 SV=2 7.94 2793.2 - 1.56E+06 - - - 1.1933 - 2.808 0.604 - 755.7 1 2 0 0.0016 14 0 0 0 2.23E+07 3.59E+05 - - - 6.0926 0.9998 221125_WJC_METTL3_EV_vs_WT_F04.15576.15576.3 5.40E-08 13/48 K.WKDSDEADLVLAK.E sp|Q13185|CBX3_HUMAN 1 1488.746 1.1 49360 15576 3 1488.745175 497.256 Chromobox protein homolog 3 OS=Homo sapiens OX=9606 GN=CBX3 PE=1 SV=4 4.23 2793.2 - 1.38E+06 - - - -0.5703 - 2.656 0.453 - 306.7 1 2 1 -0.0008 13 0 0 0 1.16E+08 1.05E+08 - - - 6.2387 1 221125_WJC_METTL3_EV_vs_WT_F04.15578.15578.3 4.66E-05 16/52 R.HFALDAAATVAAQR.D "sp|Q4VCS5|AMOT_HUMAN,tr|A6NP16|A6NP16_HUMAN,tr|E7ERM3|E7ERM3_HUMAN" 3 1440.7474 4.67 49362 15578 3 1440.745741 481.2564 Angiomotin OS=Homo sapiens OX=9606 GN=AMOT PE=1 SV=1 6.74 2793.5 - 915976 - - - -1.1244 - 3.024 0.491 - 408.3 1 2 0 -0.0016 14 0 0 0 1.35E+07 2.90E+06 - - - 6.9545 0.9999 221125_WJC_METTL3_EV_vs_WT_F04.15579.15579.2 1.40E-05 14/24 K.SGGELDIVVTSNK[136.11].E sp|Q96M27|PRRC1_HUMAN 1 1325.6918 1.96 49363 15579 2 1325.690798 663.8532 Protein PRRC1 OS=Homo sapiens OX=9606 GN=PRRC1 PE=1 SV=1 4.37 2793.6 - 620008 - - - -0.7634 - 2.792 0.539 - 1014.1 1 2 0 -0.001 13 0 0 0 1.43E+07 7.30E+06 - - - 5.6569 1 221125_WJC_METTL3_EV_vs_WT_F04.15584.15584.3 1.66E-06 17/52 K.FLESTDSFNNELK[136.11]R[166.11].L "sp|Q969G3|SMCE1_HUMAN,tr|A0A2R8Y855|A0A2R8Y855_HUMAN,tr|A0A2R8YES3|A0A2R8YES3_HUMAN,tr|A0A2U3TZQ7|A0A2U3TZQ7_HUMAN,tr|A0A2R8Y7U4|A0A2R8Y7U4_HUMAN,tr|B4DGM3|B4DGM3_HUMAN,tr|J3QKS7|J3QKS7_HUMAN,tr|A0A2R8Y4T4|A0A2R8Y4T4_HUMAN,tr|A0A2R8Y7I9|A0A2R8Y7I9_HUMAN,tr|J3QR61|J3QR61_HUMAN,tr|A0A2R8Y765|A0A2R8Y765_HUMAN" 11 1716.8438 2.22 49366 15584 3 1716.842818 573.2885 SWI\SNF-related matrix-associated actin-dependent regulator of chromatin subfamily E member 1 OS=Homo sapiens OX=9606 GN=SMARCE1 PE=1 SV=2 4.68 2794.3 - 2.24E+06 - - - -0.5627 - 3.019 0.555 - 281 1 2 0 -0.001 14 0 0 0 3.21E+07 1.44E+07 - - - 7.6638 0.9986 221125_WJC_METTL3_EV_vs_WT_F04.15588.15588.3 0.0067 Sep-40 R.K[136.11]VEGDIWALQK[136.11].D "sp|Q13405|RM49_HUMAN,tr|H0YDP7|H0YDP7_HUMAN" 2 1301.7314 1.34 49370 15588 3 1301.729814 434.9178 "39S ribosomal protein L49, mitochondrial OS=Homo sapiens OX=9606 GN=MRPL49 PE=1 SV=1" 6.07 2794.7 - 875778 - - - -1.2468 - 1.553 0.3 - 103.8 1 2 0 -0.0016 11 0 0 0 1.11E+07 8.31E+06 - - - 3.1348 1 221125_WJC_METTL3_EV_vs_WT_F04.15590.15590.2 1.85E-09 15/30 K.GNVGIGGSAVPPPPIK[136.11].H "sp|Q7Z739|YTHD3_HUMAN,tr|A0A087X0Q1|A0A087X0Q1_HUMAN,tr|A0A024R7W5|A0A024R7W5_HUMAN,tr|A0A087WY31|A0A087WY31_HUMAN" 4 1466.8337 1.43 49372 15590 2 1466.8326 734.4241 YTH domain-containing family protein 3 OS=Homo sapiens OX=9606 GN=YTHDF3 PE=1 SV=1 8.75 2795 - 725786 - - - -0.7254 - 3.001 0.666 - 497.1 1 2 0 -0.0011 16 0 0 0 4.80E+07 3.36E+07 - - - 6.6616 0.9999 221125_WJC_METTL3_EV_vs_WT_F04.15591.15591.2 7.42E-06 22-Nov K.ENDYYTPTGEFR.V sp|P46977|STT3A_HUMAN 1 1490.6314 1.27 49373 15591 2 1490.632793 746.323 Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit STT3A OS=Homo sapiens OX=9606 GN=STT3A PE=1 SV=2 4.14 2795.1 - 662441 - - - 0.9426 - 2.154 0.57 - 421.6 1 2 0 0.0014 12 0 0 0 1.44E+07 1.13E+07 - - - 5.2695 0.9965 221125_WJC_METTL3_EV_vs_WT_F04.15592.15592.3 0.00296 13/40 R.TVENIKDPLFR.F "sp|Q14204|DYHC1_HUMAN,tr|A0A7P0T9C4|A0A7P0T9C4_HUMAN,tr|A0A2R8Y706|A0A2R8Y706_HUMAN,tr|A0A7P0TAW9|A0A7P0TAW9_HUMAN,tr|A0A7P0TA13|A0A7P0TA13_HUMAN,tr|A0A7P0T9R4|A0A7P0T9R4_HUMAN,tr|A0A2R8Y5T0|A0A2R8Y5T0_HUMAN" 7 1330.7245 0.45 49374 15592 3 1330.726504 444.5821 Cytoplasmic dynein 1 heavy chain 1 OS=Homo sapiens OX=9606 GN=DYNC1H1 PE=1 SV=5 5.74 2795.2 - 659595 - - - 1.5052 - 1.894 0.308 - 179.3 1 2 1 0.002 11 0 0 0 4.38E+06 9.82E+06 - - - 3.7878 0.9999 221125_WJC_METTL3_EV_vs_WT_F04.15594.15594.2 7.70E-06 24-Nov K.FQSPYEEQLEQQR.L "sp|O00461|GOLI4_HUMAN,tr|F8W785|F8W785_HUMAN" 2 1680.7744 1.66 49376 15594 2 1680.775228 841.3945 Golgi integral membrane protein 4 OS=Homo sapiens OX=9606 GN=GOLIM4 PE=1 SV=1 4.25 2795.5 - 515567 - - - 0.514 - 2.68 0.561 - 421.7 1 2 0 0.0009 13 0 0 0 1.23E+07 7.43E+06 - - - 5.7144 0.9999 221125_WJC_METTL3_EV_vs_WT_F04.15598.15598.2 3.33E-07 14/32 R.APQTLPSPEADALAGSK.H sp|P31274|HXC9_HUMAN 1 1651.8417 2.15 49379 15598 2 1651.842049 826.9281 Homeobox protein Hox-C9 OS=Homo sapiens OX=9606 GN=HOXC9 PE=1 SV=3 4.37 2796 - 328874 - - - 0.2022 - 2.432 0.594 - 359.8 1 2 0 0.0003 17 0 0 0 1.25E+07 5.84E+06 - - - 5.6131 1 221125_WJC_METTL3_EV_vs_WT_F04.15600.15600.3 2.22E-07 19/72 R.GLLQDDAHPTLVTYADHSK[136.11].L "sp|Q86U44|MTA70_HUMAN,tr|F5H6D8|F5H6D8_HUMAN,tr|H0YFV6|H0YFV6_HUMAN,tr|B4DTN4|B4DTN4_HUMAN" 4 2088.0367 0.02 49380 15600 3 2088.035538 697.0195 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 5.13 2796.2 - 6.43E+06 - - - -0.5723 - 3.487 0.569 - 335 1 2 0 -0.0012 19 0 0 0 2.25E+06 1.35E+08 - - - 7.9521 1 221125_WJC_METTL3_EV_vs_WT_F04.15602.15602.3 2.15E-09 16/52 R.VHVTQEDFEMAVAK.V sp|P62195|PRS8_HUMAN 1 1602.7712 0.94 49382 15602 3 1602.772093 535.2643 26S proteasome regulatory subunit 8 OS=Homo sapiens OX=9606 GN=PSMC5 PE=1 SV=1 4.65 2796.3 - 1.36E+06 - - - 0.5615 - 3.18 0.626 - 407.9 1 2 0 0.0009 14 0 0 0 9.73E+06 1.04E+07 - - - 8.5935 0.9999 221125_WJC_METTL3_EV_vs_WT_F04.15604.15604.3 0.0154 Dec-36 K.K[136.11]QELLEALTK[136.11].H "sp|P12956|XRCC6_HUMAN,tr|B1AHC9|B1AHC9_HUMAN" 2 1187.7096 1.05 49384 15604 3 1187.710338 396.9105 X-ray repair cross-complementing protein 6 OS=Homo sapiens OX=9606 GN=XRCC6 PE=1 SV=2 6.14 2796.6 - 1.21E+06 - - - 0.5885 - 2.558 0.414 - 205.8 1 2 0 0.0007 10 0 0 0 3.99E+07 3.79E+07 - - - 5.8984 0.9999 221125_WJC_METTL3_EV_vs_WT_F04.15606.15606.3 2.64E-05 Nov-68 K.YGQFSGLNPGGRPITPPR.N "sp|P62136|PP1A_HUMAN,tr|A0A7I2V4F7|A0A7I2V4F7_HUMAN,tr|E9PMD7|E9PMD7_HUMAN" 3 1912.9908 2.56 49386 15606 3 1912.990297 638.6709 Serine\threonine-protein phosphatase PP1-alpha catalytic subunit OS=Homo sapiens OX=9606 GN=PPP1CA PE=1 SV=1 10.84 2796.9 - 635865 - - - -0.2525 - 1.912 0.429 - 125.5 1 2 0 -0.0005 18 0 0 0 7.46E+06 2.91E+06 - - - 4.9368 0.9999 221125_WJC_METTL3_EV_vs_WT_F04.15607.15607.3 0.000326 15/48 R.LLEEQLQHEISNK[136.11].M sp|Q86UP2|KTN1_HUMAN 1 1587.8348 1.79 49387 15607 3 1587.830897 530.2855 Kinectin OS=Homo sapiens OX=9606 GN=KTN1 PE=1 SV=1 4.75 2797 - 575196 - - - -2.4492 - 2.557 0.458 - 267.2 1 2 0 -0.0039 13 0 0 0 1.13E+07 6.32E+06 - - - 6.1906 1 221125_WJC_METTL3_EV_vs_WT_F04.15609.15609.3 1.96E-05 13/36 R.R[166.11]VLQALEGLK[136.11].M "sp|P39019|RS19_HUMAN,tr|A0A075B6E2|A0A075B6E2_HUMAN" 2 1143.7095 0.001 49389 15609 3 1143.707857 382.2438 40S ribosomal protein S19 OS=Homo sapiens OX=9606 GN=RPS19 PE=1 SV=2 8.75 2797.3 - 516443 - - - -1.4042 - 2.65 0.459 - 278.5 1 2 0 -0.0016 10 0 0 0 0.00E+00 4.52E+07 - - - 6.5031 1 221125_WJC_METTL3_EV_vs_WT_F04.15611.15611.2 4.66E-09 16/30 R.IMDPNIVGSEHYDVAR.G "sp|P06576|ATPB_HUMAN,tr|H0YH81|H0YH81_HUMAN" 2 1814.8621 1.95 49391 15611 2 1814.853449 908.4383 "ATP synthase subunit beta, mitochondrial OS=Homo sapiens OX=9606 GN=ATP5F1B PE=1 SV=3" 4.54 2797.5 - 356847 - - - -4.7849 - 2.822 0.686 - 719.1 1 2 0 -0.0087 16 0 0 0 3.69E+06 1.89E+06 - - - 6.6557 1 221125_WJC_METTL3_EV_vs_WT_F04.15612.15612.2 3.72E-10 Nov-42 R.LIPNATGTGTFSPGASPGSEAR.T "sp|Q16512|PKN1_HUMAN,tr|K7EN76|K7EN76_HUMAN" 2 2087.0283 5.41 49392 15612 2 2087.026346 1044.5214 Serine\threonine-protein kinase N1 OS=Homo sapiens OX=9606 GN=PKN1 PE=1 SV=2 6 2797.6 - 188748 - - - -0.9588 - 2.682 0.684 - 198.3 1 2 0 -0.002 22 0 0 0 4.19E+06 7.75E+05 - - - 6.5179 1 221125_WJC_METTL3_EV_vs_WT_F04.15616.15616.3 5.76E-10 21/60 R.IMDPNIVGSEHYDVAR.G "sp|P06576|ATPB_HUMAN,tr|H0YH81|H0YH81_HUMAN" 2 1814.8621 1.78 49395 15616 3 1814.862449 605.9613 "ATP synthase subunit beta, mitochondrial OS=Homo sapiens OX=9606 GN=ATP5F1B PE=1 SV=3" 4.54 2797.9 - 2.44E+07 - - - 0.1741 - 3.528 0.618 - 651.7 1 2 0 0.0003 16 0 0 0 1.80E+08 1.01E+08 - - - 8.6649 1 221125_WJC_METTL3_EV_vs_WT_F04.15617.15617.3 1.65E-05 18/56 K.DVDAAYMNKVELQAK.A "sp|P48668|K2C6C_HUMAN,sp|P04259|K2C6B_HUMAN,sp|Q14CN4|K2C72_HUMAN,sp|P02538|K2C6A_HUMAN" 4 1693.8345 230.28 49396 15617 3 1693.834647 565.6188 "Keratin, type II cytoskeletal 6C OS=Homo sapiens OX=9606 GN=KRT6C PE=1 SV=3" 4.56 2798 - 1.05E+07 - - - 0.0738 - 3.462 0.589 - 247 1 2 1 0.0001 15 0 0 0 1.89E+08 8.20E+05 - - - 8.3472 0.9999 221125_WJC_METTL3_EV_vs_WT_F04.15618.15618.4 7.54E-06 12/108 R.GLLQDDAHPTLVTYADHSK[136.11].L "sp|Q86U44|MTA70_HUMAN,tr|F5H6D8|F5H6D8_HUMAN,tr|H0YFV6|H0YFV6_HUMAN,tr|B4DTN4|B4DTN4_HUMAN" 4 2088.0367 0.02 49397 15618 4 2088.035596 523.0165 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 5.13 2798 - 7.24E+06 - - - -0.5445 - 2.251 0.476 - 52.7 1 2 0 -0.0011 19 0 0 0 7.38E+06 3.31E+08 - - - 3.6433 1 221125_WJC_METTL3_EV_vs_WT_F04.15619.15619.2 1.27E-07 16/30 K.GNVGIGGSAVPPPPIK.H "sp|Q7Z739|YTHD3_HUMAN,tr|A0A087X0Q1|A0A087X0Q1_HUMAN,tr|A0A024R7W5|A0A024R7W5_HUMAN,tr|A0A087WY31|A0A087WY31_HUMAN" 4 1458.8195 1.43 49398 15619 2 1458.819286 730.417 YTH domain-containing family protein 3 OS=Homo sapiens OX=9606 GN=YTHDF3 PE=1 SV=1 8.75 2798.1 - 3.09E+06 - - - -0.122 - 3.183 0.645 - 575.6 1 2 0 -0.0002 16 0 0 0 4.80E+07 3.36E+07 - - - 6.6515 0.9992 221125_WJC_METTL3_EV_vs_WT_F04.15620.15620.2 0.216 18-Dec R.R[166.11]VLQALEGLK[136.11].M "sp|P39019|RS19_HUMAN,tr|A0A075B6E2|A0A075B6E2_HUMAN" 2 1143.7095 1.11 49399 15620 2 1143.708972 572.862 40S ribosomal protein S19 OS=Homo sapiens OX=9606 GN=RPS19 PE=1 SV=2 8.75 2798.1 - 1.89E+06 - - - -0.4293 - 1.996 0.212 - 521.9 1 2 0 -0.0005 10 0 0 0 2.44E+08 2.19E+08 - - - 2.5359 1 221125_WJC_METTL3_EV_vs_WT_F04.15622.15622.2 0.00103 17/28 R.AGGADAVQTVTGGLR.S sp|Q9H223|EHD4_HUMAN 1 1371.7106 1.86 49401 15622 2 1371.709139 686.8626 EH domain-containing protein 4 OS=Homo sapiens OX=9606 GN=EHD4 PE=1 SV=1 5.88 2798.3 - 1.71E+06 - - - -1.0957 - 3.241 0.533 - 946.5 1 2 0 -0.0015 15 0 0 0 3.95E+07 2.13E+07 - - - 5.8682 0.9999 221125_WJC_METTL3_EV_vs_WT_F04.15623.15623.2 4.62E-06 24-Nov R.NIQDTSDLDAIAK[136.11].D "sp|Q9NZB2|F120A_HUMAN,tr|A0A0C4DH52|A0A0C4DH52_HUMAN" 2 1410.7082 0.86 49402 15623 2 1410.707665 706.3614 Constitutive coactivator of PPAR-gamma-like protein 1 OS=Homo sapiens OX=9606 GN=FAM120A PE=1 SV=2 3.93 2798.4 - 1.58E+06 - - - -0.3714 - 2.43 0.54 - 238.6 1 2 0 -0.0005 13 0 0 0 1.26E+07 1.47E+07 - - - 5.3081 0.9985 221125_WJC_METTL3_EV_vs_WT_F04.15624.15624.3 0.00112 13/64 K.TAASGIPYHSEVPVSLK.E "sp|Q01082|SPTB2_HUMAN,tr|A0A087WUZ3|A0A087WUZ3_HUMAN" 2 1754.9203 1.43 49403 15624 3 1754.924723 585.9807 "Spectrin beta chain, non-erythrocytic 1 OS=Homo sapiens OX=9606 GN=SPTBN1 PE=1 SV=2" 6.41 2798.5 - 678774 - - - 2.5203 - 2.279 0.283 - 104.4 1 2 0 0.0044 17 0 0 0 3.27E+06 2.29E+06 - - - 3.775 1 221125_WJC_METTL3_EV_vs_WT_F04.15625.15625.2 1.37E-10 17/28 K.DVDAAYMNKVELQAK.A "sp|P48668|K2C6C_HUMAN,sp|P04259|K2C6B_HUMAN,sp|Q14CN4|K2C72_HUMAN,sp|P02538|K2C6A_HUMAN" 4 1693.8345 999 49404 15625 2 1693.834801 847.9245 "Keratin, type II cytoskeletal 6C OS=Homo sapiens OX=9606 GN=KRT6C PE=1 SV=3" 4.56 2798.6 - 663382 - - - 0.1647 - 3.629 0.639 - 790.9 1 2 1 0.0003 15 0 0 0 1.13E+07 0.00E+00 - - - 6.9295 0.9912 221125_WJC_METTL3_EV_vs_WT_F04.15627.15627.3 0.656 Nov-40 R.KVEGDIWALQK.D "sp|Q13405|RM49_HUMAN,tr|H0YDP7|H0YDP7_HUMAN" 2 1285.703 1.35 49406 15627 3 1285.70238 429.575 "39S ribosomal protein L49, mitochondrial OS=Homo sapiens OX=9606 GN=MRPL49 PE=1 SV=1" 6.07 2798.9 - 400728 - - - -0.511 - 1.733 0.16 - 183.4 1 2 0 -0.0007 11 0 0 0 1.09E+07 8.04E+06 - - - 1.8857 0.9997 221125_WJC_METTL3_EV_vs_WT_F04.15628.15628.3 5.94E-05 Dec-60 K.MHGGGPTVTAGLPLPK.A "sp|P11586|C1TC_HUMAN,tr|F5H2F4|F5H2F4_HUMAN,tr|V9GZ78|V9GZ78_HUMAN,tr|V9GYY3|V9GYY3_HUMAN,tr|A0A494C1T2|A0A494C1T2_HUMAN" 5 1531.8181 1.17 49407 15628 3 1531.817561 511.6133 "C-1-tetrahydrofolate synthase, cytoplasmic OS=Homo sapiens OX=9606 GN=MTHFD1 PE=1 SV=4" 8.52 2799 - 335831 - - - -0.3414 - 2.18 0.338 - 170.8 1 2 0 -0.0005 16 0 0 0 1.01E+07 8.60E+06 - - - 4.3079 0.9999 221125_WJC_METTL3_EV_vs_WT_F04.15630.15630.2 1.39E-06 13/26 K.LSQPPLEQTQLQVK[136.11].T "sp|Q7Z589|EMSY_HUMAN,tr|H0YET8|H0YET8_HUMAN,tr|E9PMC9|E9PMC9_HUMAN" 3 1615.9025 0.66 49409 15630 2 1615.90347 808.9585 BRCA2-interacting transcriptional repressor EMSY OS=Homo sapiens OX=9606 GN=EMSY PE=1 SV=2 6 2799.3 - 326571 - - - 0.6176 - 2.419 0.561 - 381 1 2 0 0.001 14 0 0 0 2.09E+06 3.18E+06 - - - 5.401 0.9998 221125_WJC_METTL3_EV_vs_WT_F04.15631.15631.3 0.0018 Sep-48 R.GYHYATC[160.03]LEGALK.L "sp|Q06210|GFPT1_HUMAN,tr|A0A6I8PRN4|A0A6I8PRN4_HUMAN" 2 1481.6973 35.4 49410 15631 3 1481.696932 494.9064 Glutamine--fructose-6-phosphate aminotransferase [isomerizing] 1 OS=Homo sapiens OX=9606 GN=GFPT1 PE=1 SV=3 6.74 2799.4 - 332125 - - - -0.2484 - 1.997 0.391 - 135.9 1 2 0 -0.0004 13 0 0 0 4.78E+06 1.35E+05 - - - 4.7744 0.9309 221125_WJC_METTL3_EV_vs_WT_F04.15636.15636.2 0.0364 20-Oct L.SVEADINGLRR.V "sp|Q04695|K1C17_HUMAN,sp|P13645|K1C10_HUMAN,sp|P02533|K1C14_HUMAN,sp|Q7Z3Y8|K1C27_HUMAN,sp|P08727|K1C19_HUMAN,sp|P13646|K1C13_HUMAN,tr|C9JM50|C9JM50_HUMAN,tr|A0A1B0GVI3|A0A1B0GVI3_HUMAN,tr|K7EMD9|K7EMD9_HUMAN,tr|F5GWP8|F5GWP8_HUMAN,tr|K7EMS3|K7EMS3_HUMAN,tr|K7ERE3|K7ERE3_HUMAN" 12 1228.6524 30.94 49413 15636 2 1228.654264 615.3335 "Keratin, type I cytoskeletal 17 OS=Homo sapiens OX=9606 GN=KRT17 PE=1 SV=2" 5.79 2799.9 - 3.02E+06 - - - 1.5187 - 1.589 0.323 - 120.5 1 1 0 0.0019 11 0 0 0 2.24E+07 7.25E+05 - - - 2.6789 1 221125_WJC_METTL3_EV_vs_WT_F04.15637.15637.3 4.64E-08 14/52 K.NMQNVEHVPLSLDR[166.11].A sp|P20618|PSB1_HUMAN 1 1660.8231 0.99 49414 15637 3 1660.819186 554.615 Proteasome subunit beta type-1 OS=Homo sapiens OX=9606 GN=PSMB1 PE=1 SV=2 5.32 2800 - 2.34E+06 - - - -2.332 - 2.623 0.599 - 217.1 1 2 0 -0.0039 14 0 0 0 1.68E+07 1.70E+07 - - - 7.7799 0.9983 221125_WJC_METTL3_EV_vs_WT_F04.15638.15638.2 7.52E-09 15/24 K.WKDSDEADLVLAK.E sp|Q13185|CBX3_HUMAN 1 1488.746 0.97 49415 15638 2 1488.7472 745.3803 Chromobox protein homolog 3 OS=Homo sapiens OX=9606 GN=CBX3 PE=1 SV=4 4.23 2800.1 - 1.56E+06 - - - 0.7899 - 2.379 0.475 - 595.7 1 2 1 0.0012 13 0 0 0 1.27E+07 1.31E+07 - - - 4.7733 0.9998 221125_WJC_METTL3_EV_vs_WT_F04.15639.15639.2 2.20E-05 18-Oct R.QVLDNLTMEK.S "sp|P35527|K1C9_HUMAN,tr|K7EQQ3|K7EQQ3_HUMAN" 2 1189.6013 999 49416 15639 2 1189.602058 595.8079 "Keratin, type I cytoskeletal 9 OS=Homo sapiens OX=9606 GN=KRT9 PE=1 SV=3" 4.37 2800.2 - 1.27E+06 - - - 0.659 - 2.157 0.435 - 317.7 1 2 0 0.0008 10 0 0 0 1.68E+07 0.00E+00 - - - 4.3994 0.9993 221125_WJC_METTL3_EV_vs_WT_F04.15640.15640.3 0.000551 Nov-44 K.GK[136.11]LDVQFSGLTK[136.11].G "sp|P21333|FLNA_HUMAN,tr|A0A7P0NMY4|A0A7P0NMY4_HUMAN,tr|Q60FE5|Q60FE5_HUMAN" 3 1307.742 0.94 49417 15640 3 1307.742324 436.9213 Filamin-A OS=Homo sapiens OX=9606 GN=FLNA PE=1 SV=4 8.59 2800.3 - 888713 - - - 0.2462 - 1.972 0.39 - 141.3 1 2 1 0.0003 12 0 0 0 5.39E+06 5.70E+06 - - - 4.7702 0.9986 221125_WJC_METTL3_EV_vs_WT_F04.15643.15643.3 0.00131 Nov-44 K.GKLDVQFSGLTK.G "sp|P21333|FLNA_HUMAN,tr|A0A7P0NMY4|A0A7P0NMY4_HUMAN,tr|Q60FE5|Q60FE5_HUMAN" 3 1291.7136 0.94 49420 15643 3 1291.710945 431.5785 Filamin-A OS=Homo sapiens OX=9606 GN=FLNA PE=1 SV=4 8.59 2800.7 - 656636 - - - -2.057 - 1.91 0.398 - 168.3 1 2 1 -0.0027 12 0 0 0 5.39E+06 5.70E+06 - - - 4.7702 0.9974 221125_WJC_METTL3_EV_vs_WT_F04.15645.15645.2 0.000423 24-Oct K.ILDSVGIEADDDR[166.11].L sp|P05387|RLA2_HUMAN 1 1426.6815 1.36 49422 15645 2 1426.68702 714.348 60S acidic ribosomal protein P2 OS=Homo sapiens OX=9606 GN=RPLP2 PE=1 SV=1 3.71 2800.9 - 446284 - - - 3.853 - 1.878 0.395 - 239.1 1 2 0 0.0055 13 0 0 0 4.39E+06 3.23E+06 - - - 3.5742 0.9999 221125_WJC_METTL3_EV_vs_WT_F04.15646.15646.3 0.00163 Nov-72 K.NLPPSGAVPVTGIPPHVVK.V "sp|Q13283|G3BP1_HUMAN,tr|A0A7I2V5M7|A0A7I2V5M7_HUMAN,tr|A0A7I2YQM1|A0A7I2YQM1_HUMAN,tr|A0A7P0P2U7|A0A7P0P2U7_HUMAN,tr|A0A7I2YQU8|A0A7I2YQU8_HUMAN,tr|A0A7I2V548|A0A7I2V548_HUMAN,tr|A0A7I2V651|A0A7I2V651_HUMAN,tr|A0A7I2V4D8|A0A7I2V4D8_HUMAN,tr|A0A7I2YQN9|A0A7I2YQN9_HUMAN" 9 1878.0727 1.19 49423 15646 3 1878.072981 627.0315 Ras GTPase-activating protein-binding protein 1 OS=Homo sapiens OX=9606 GN=G3BP1 PE=1 SV=1 8.76 2801 - 431571 - - - 0.14 - 2.348 0.425 - 88.4 1 2 0 0.0003 19 0 0 0 3.17E+06 2.66E+06 - - - 5.3753 1 221125_WJC_METTL3_EV_vs_WT_F04.15648.15648.2 2.07E-09 14/32 K.WLEEADSSTGSPTSIDK.L "sp|P20264|PO3F3_HUMAN,sp|P49335|PO3F4_HUMAN,tr|A0A2R8Y739|A0A2R8Y739_HUMAN" 3 1821.8269 1.84 49425 15648 2 1821.828234 911.9207 "POU domain, class 3, transcription factor 3 OS=Homo sapiens OX=9606 GN=POU3F3 PE=1 SV=2" 3.92 2801.3 - 334736 - - - 0.758 - 2.822 0.699 - 469.4 1 2 0 0.0014 17 0 0 0 3.23E+06 1.75E+06 - - - 6.754 0.8934 221125_WJC_METTL3_EV_vs_WT_F04.15649.15649.3 1.78 Oct-60 K.MHGGGPTVTAGLPLPK[136.11].A "sp|P11586|C1TC_HUMAN,tr|F5H2F4|F5H2F4_HUMAN,tr|V9GZ78|V9GZ78_HUMAN,tr|V9GYY3|V9GYY3_HUMAN,tr|A0A494C1T2|A0A494C1T2_HUMAN" 5 1539.8323 1.13 49426 15649 3 1539.833009 514.2847 "C-1-tetrahydrofolate synthase, cytoplasmic OS=Homo sapiens OX=9606 GN=MTHFD1 PE=1 SV=4" 8.52 2801.4 - 324031 - - - 0.4708 - 1.518 0.084 - 69.7 2 2 0 0.0007 16 0 0 0 4.32E+06 3.81E+06 - - - 0.408 0.9999 221125_WJC_METTL3_EV_vs_WT_F04.15652.15652.2 1.44E-06 26-Aug K.FNSQPVGDC[160.03]DFNVR[166.11].L sp|O60942|MCE1_HUMAN 1 1663.7288 0.87 49429 15652 2 1663.72744 832.8717 mRNA-capping enzyme OS=Homo sapiens OX=9606 GN=RNGTT PE=1 SV=1 4.21 2801.8 - 178393 - - - -0.8325 - 1.782 0.579 - 181.9 1 2 0 -0.0014 14 0 0 0 9.86E+05 1.13E+06 - - - 4.7669 1 221125_WJC_METTL3_EV_vs_WT_F04.15655.15655.2 0.000166 24-Nov R.FSGSGSGTDFTLK.L "sp|A2NJV5|KV229_HUMAN,sp|A0A087WW87|KV240_HUMAN,sp|P06310|KV230_HUMAN,sp|A0A075B6S2|KVD29_HUMAN,sp|P01614|KVD40_HUMAN,sp|P01615|KVD28_HUMAN,sp|A0A075B6S6|KVD30_HUMAN,sp|A0A075B6P5|KV228_HUMAN,sp|A0A0A0MRZ7|KVD26_HUMAN" 9 1302.6092 999 49431 15655 2 1302.608968 652.3119 Immunoglobulin kappa variable 2-29 OS=Homo sapiens OX=9606 GN=IGKV2-29 PE=3 SV=2 5.84 2802.2 - 5.62E+06 - - - -0.175 - 2.423 0.598 - 210.4 1 2 0 -0.0002 13 0 0 0 1.94E+08 0.00E+00 - - - 5.7292 0.9712 221125_WJC_METTL3_EV_vs_WT_F04.15657.15657.3 0.000233 Nov-60 K.GNVGIGGSAVPPPPIK.H "sp|Q7Z739|YTHD3_HUMAN,tr|A0A087X0Q1|A0A087X0Q1_HUMAN,tr|A0A024R7W5|A0A024R7W5_HUMAN,tr|A0A087WY31|A0A087WY31_HUMAN" 4 1458.8195 2.09 49432 15657 3 1458.813889 487.2804 YTH domain-containing family protein 3 OS=Homo sapiens OX=9606 GN=YTHDF3 PE=1 SV=1 8.75 2802.4 - 1.63E+06 - - - -3.8216 - 2.083 0.171 - 170.8 1 2 0 -0.0056 16 0 0 0 1.02E+07 4.90E+06 - - - 2.3278 0.9992 221125_WJC_METTL3_EV_vs_WT_F04.15658.15658.2 0.00303 16-Jul K.DNLPIQIQK.L sp|Q96SI9|STRBP_HUMAN 1 1067.5975 0.46 49433 15658 2 1067.598057 534.806 Spermatid perinuclear RNA-binding protein OS=Homo sapiens OX=9606 GN=STRBP PE=1 SV=1 5.84 2802.5 - 1.09E+06 - - - 0.5133 - 1.476 0.333 - 164.3 1 2 0 0.0005 9 0 0 0 8.76E+06 1.92E+07 - - - 2.6267 0.9998 221125_WJC_METTL3_EV_vs_WT_F04.15659.15659.3 0.000291 Dec-60 K.GNVGIGGSAVPPPPIK[136.11].H "sp|Q7Z739|YTHD3_HUMAN,tr|A0A087X0Q1|A0A087X0Q1_HUMAN,tr|A0A024R7W5|A0A024R7W5_HUMAN,tr|A0A087WY31|A0A087WY31_HUMAN" 4 1466.8337 2.23 49434 15659 3 1466.835637 489.9518 YTH domain-containing family protein 3 OS=Homo sapiens OX=9606 GN=YTHDF3 PE=1 SV=1 8.75 2802.6 - 775550 - - - 1.3451 - 2.304 0.356 - 175.2 1 2 0 0.002 16 0 0 0 9.64E+06 4.32E+06 - - - 4.6501 0.9998 221125_WJC_METTL3_EV_vs_WT_F04.15660.15660.3 1.08E-05 14/56 R.AGGADAVQTVTGGLR.S sp|Q9H223|EHD4_HUMAN 1 1371.7106 2.23 49435 15660 3 1371.712607 458.2442 EH domain-containing protein 4 OS=Homo sapiens OX=9606 GN=EHD4 PE=1 SV=1 5.88 2802.7 - 758882 - - - 1.4325 - 2.437 0.371 - 245.2 1 2 0 0.002 15 0 0 0 4.68E+06 2.10E+06 - - - 5.0001 0.9491 221125_WJC_METTL3_EV_vs_WT_F04.15661.15661.2 0.00883 18-Jul M.FDQSQIQEFK[136.11].E "sp|O14950|ML12B_HUMAN,sp|P19105|ML12A_HUMAN,sp|P24844|MYL9_HUMAN,sp|Q9BUA6|MYL10_HUMAN,tr|A0A2R8YDI2|A0A2R8YDI2_HUMAN,tr|J3KTJ1|J3KTJ1_HUMAN,tr|J3QRS3|J3QRS3_HUMAN" 7 1276.6179 0.94 49436 15661 2 1276.617319 639.3162 Myosin regulatory light chain 12B OS=Homo sapiens OX=9606 GN=MYL12B PE=1 SV=2 4.37 2802.8 - 696121 - - - -0.4684 - 1.548 0.302 - 131.6 1 1 0 -0.0006 10 0 0 0 3.91E+06 4.16E+06 - - - 2.4911 1 221125_WJC_METTL3_EV_vs_WT_F04.15662.15662.2 3.01E-11 15/30 K.ETGDPGGQLVLAGDPR.Q "sp|Q9HCE1|MOV10_HUMAN,tr|Q5JR04|Q5JR04_HUMAN" 2 1580.7794 1.01 49437 15662 2 1580.779842 791.397 Helicase MOV-10 OS=Homo sapiens OX=9606 GN=MOV10 PE=1 SV=2 4.03 2802.9 - 672333 - - - 0.248 - 3.284 0.637 - 304.4 1 2 0 0.0004 16 0 0 0 4.18E+06 4.15E+06 - - - 6.6691 0.938 221125_WJC_METTL3_EV_vs_WT_F04.15664.15664.3 0.245 Sep-44 K.EPLWIRPDAPSR.C "sp|P35520|CBS_HUMAN,tr|C9JMA6|C9JMA6_HUMAN" 2 1435.7572 0.61 49439 15664 3 1435.759672 479.593 Cystathionine beta-synthase OS=Homo sapiens OX=9606 GN=CBS PE=1 SV=2 6.17 2803.2 - 616011 - - - 1.7231 - 1.647 0.097 - 148.9 1 2 0 0.0025 12 0 0 0 5.36E+06 8.85E+06 - - - 1.0038 0.9878 221125_WJC_METTL3_EV_vs_WT_F04.15665.15665.3 0.00467 Dec-60 R.LITNSEEIAFYNGNK[136.11]R[166.11].E "sp|P28288|ABCD3_HUMAN,tr|A0A3B3ITW3|A0A3B3ITW3_HUMAN" 2 1885.9653 0.6 49440 15665 3 1885.960921 629.6624 ATP-binding cassette sub-family D member 3 OS=Homo sapiens OX=9606 GN=ABCD3 PE=1 SV=1 6.14 2803.3 - 602256 - - - -2.3203 - 2.032 0.164 - 65.4 1 2 0 -0.0044 16 0 0 0 2.78E+06 4.62E+06 - - - 2.1865 1 221125_WJC_METTL3_EV_vs_WT_F04.15666.15666.2 3.86E-11 14/30 K.ETGDPGGQLVLAGDPR[166.11].Q "sp|Q9HCE1|MOV10_HUMAN,tr|Q5JR04|Q5JR04_HUMAN" 2 1590.7877 1.01 49441 15666 2 1590.789309 796.4011 Helicase MOV-10 OS=Homo sapiens OX=9606 GN=MOV10 PE=1 SV=2 4.03 2803.4 - 594128 - - - 0.9989 - 2.571 0.672 - 232.4 1 2 0 0.0016 16 0 0 0 4.18E+06 4.15E+06 - - - 6.3255 1 221125_WJC_METTL3_EV_vs_WT_F04.15668.15668.2 3.92E-08 Nov-40 K.LYGSAGPPPTGEEDTAEK[136.11]DEL.- "sp|P11021|BIP_HUMAN,tr|A0A7P0TB36|A0A7P0TB36_HUMAN,tr|A0A7P0TAI0|A0A7P0TAI0_HUMAN" 3 2182.9997 0.67 49443 15668 2 2183.002197 1092.5071 Endoplasmic reticulum chaperone BiP OS=Homo sapiens OX=9606 GN=HSPA5 PE=1 SV=2 3.77 2803.7 - 453804 - - - 1.126 - 2.343 0.65 - 226.7 1 2 1 0.0025 21 0 0 0 1.92E+07 2.87E+07 - - - 5.9344 0.9999 221125_WJC_METTL3_EV_vs_WT_F04.15669.15669.3 0.000605 14/40 K.SFR[166.11]PGDIVLAK[136.11].V "sp|Q9Y3B2|EXOS1_HUMAN,tr|B1AMU3|B1AMU3_HUMAN,tr|B1AMU7|B1AMU7_HUMAN" 3 1219.7044 0.75 49444 15669 3 1219.706378 407.5754 Exosome complex component CSL4 OS=Homo sapiens OX=9606 GN=EXOSC1 PE=1 SV=1 8.46 2803.8 - 443330 - - - 1.6397 - 2.642 0.407 - 263.7 1 2 0 0.002 11 0 0 0 4.82E+06 6.46E+06 - - - 5.8371 0.9999 221125_WJC_METTL3_EV_vs_WT_F04.15670.15670.3 0.000709 15/44 R.DRLVPGPVFGSK.D "sp|Q12907|LMAN2_HUMAN,tr|D6RBV2|D6RBV2_HUMAN,tr|D6RBH1|D6RBH1_HUMAN,tr|D6RIU4|D6RIU4_HUMAN" 4 1270.7034 0.29 49445 15670 3 1270.702014 424.5751 Vesicular integral-membrane protein VIP36 OS=Homo sapiens OX=9606 GN=LMAN2 PE=1 SV=1 8.75 2803.9 - 423369 - - - -1.0679 - 2.854 0.503 - 558.1 1 2 1 -0.0014 12 0 0 0 3.89E+06 1.34E+07 - - - 7.0545 0.9999 221125_WJC_METTL3_EV_vs_WT_F04.15674.15674.3 2.70E-05 Sep-32 K.FYVHNDMFR.Y "sp|Q9UN86|G3BP2_HUMAN,tr|A0A7I2V3E2|A0A7I2V3E2_HUMAN,tr|A0A7I2V647|A0A7I2V647_HUMAN,tr|H0YAE3|H0YAE3_HUMAN,tr|D6RAC7|D6RAC7_HUMAN,tr|D6RB17|D6RB17_HUMAN,tr|A0A7I2YQS2|A0A7I2YQS2_HUMAN,tr|A0A7I2YQD9|A0A7I2YQD9_HUMAN,tr|A0A7I2V3R7|A0A7I2V3R7_HUMAN,tr|A0A7I2V481|A0A7I2V481_HUMAN,tr|A0A7I2V3P9|A0A7I2V3P9_HUMAN" 11 1227.5495 1.22 49449 15674 3 1227.551977 410.1904 Ras GTPase-activating protein-binding protein 2 OS=Homo sapiens OX=9606 GN=G3BP2 PE=1 SV=2 6.74 2804.4 - 305625 - - - 2.0073 - 1.979 0.492 - 95.2 1 2 0 0.0025 9 0 0 0 3.40E+06 2.78E+06 - - - 6.0818 0.9966 221125_WJC_METTL3_EV_vs_WT_F04.15675.15675.2 0.0746 28-Jun K.EGGPAFEAGLC[160.03]TGDR.L "sp|Q5T5U3|RHG21_HUMAN,tr|A0A087WW76|A0A087WW76_HUMAN,tr|E7ESW5|E7ESW5_HUMAN,tr|A0A7P0TAS2|A0A7P0TAS2_HUMAN,tr|A0A805TBS0|A0A805TBS0_HUMAN,tr|H0Y5T2|H0Y5T2_HUMAN,tr|A0A452Q6Z5|A0A452Q6Z5_HUMAN" 7 1535.6675 5.48 49450 15675 2 1535.664873 768.841 Rho GTPase-activating protein 21 OS=Homo sapiens OX=9606 GN=ARHGAP21 PE=1 SV=2 4.14 2804.6 - 283224 - - - -1.682 - 1.153 0.326 - 92.3 1 2 0 -0.0026 15 0 0 0 1.72E+06 3.14E+05 - - - 1.798 0.9986 221125_WJC_METTL3_EV_vs_WT_F04.15676.15676.2 4.48E-07 Aug-40 K.LYGSAGPPPTGEEDTAEKDEL.- "sp|P11021|BIP_HUMAN,tr|A0A7P0TB36|A0A7P0TB36_HUMAN,tr|A0A7P0TAI0|A0A7P0TAI0_HUMAN" 3 2174.9855 0.66 49451 15676 2 2174.987723 1088.5 Endoplasmic reticulum chaperone BiP OS=Homo sapiens OX=9606 GN=HSPA5 PE=1 SV=2 3.77 2804.7 - 278907 - - - 1.0041 - 1.952 0.628 - 118.8 1 2 1 0.0022 21 0 0 0 2.45E+07 3.74E+07 - - - 5.3231 0.9997 221125_WJC_METTL3_EV_vs_WT_F04.15678.15678.3 0.00589 Oct-52 K.VEQVLSLEPQHELK[136.11].F "sp|O95292|VAPB_HUMAN,tr|E5RK64|E5RK64_HUMAN" 2 1655.8974 1.14 49452 15678 3 1655.898995 552.9731 Vesicle-associated membrane protein-associated protein B\C OS=Homo sapiens OX=9606 GN=VAPB PE=1 SV=3 4.75 2804.9 - 1.24E+06 - - - 0.9717 - 1.91 0.362 - 117.9 1 2 0 0.0016 14 0 0 0 5.67E+07 4.96E+07 - - - 4.2952 0.9996 221125_WJC_METTL3_EV_vs_WT_F04.15679.15679.3 5.11E-05 Nov-80 K.LYGSAGPPPTGEEDTAEKDEL.- "sp|P11021|BIP_HUMAN,tr|A0A7P0TB36|A0A7P0TB36_HUMAN,tr|A0A7P0TAI0|A0A7P0TAI0_HUMAN" 3 2174.9855 0.63 49453 15679 3 2174.988307 726.0025 Endoplasmic reticulum chaperone BiP OS=Homo sapiens OX=9606 GN=HSPA5 PE=1 SV=2 3.77 2805.1 - 368486 - - - 1.2727 - 2.183 0.473 - 96.1 1 2 1 0.0028 21 0 0 0 3.22E+07 5.15E+07 - - - 5.6844 0.9999 221125_WJC_METTL3_EV_vs_WT_F04.15684.15684.4 7.16E-06 15/108 R.VIHLSNLPHSGYSDSAVLK.L "sp|P43243|MATR3_HUMAN,tr|B3KM87|B3KM87_HUMAN,tr|A8MXP9|A8MXP9_HUMAN,tr|D6RBK5|D6RBK5_HUMAN,tr|A0A0R4J2E8|A0A0R4J2E8_HUMAN,tr|H0Y8T4|H0Y8T4_HUMAN,tr|D6REM6|D6REM6_HUMAN" 7 2036.0691 1.41 49458 15684 4 2036.072136 510.0245 Matrin-3 OS=Homo sapiens OX=9606 GN=MATR3 PE=1 SV=2 6.89 2805.4 - 1.04E+06 - - - 1.496 - 2.544 0.418 - 173.6 1 2 0 0.003 19 0 0 0 3.81E+06 2.71E+06 - - - 3.1793 0.9994 221125_WJC_METTL3_EV_vs_WT_F04.15685.15685.3 6.70E-05 15/48 K.LQEELDKYSQALR.K "sp|Q15643|TRIPB_HUMAN,tr|H0YJ97|H0YJ97_HUMAN" 2 1591.8206 1.24 49459 15685 3 1591.824864 531.6141 Thyroid receptor-interacting protein 11 OS=Homo sapiens OX=9606 GN=TRIP11 PE=1 SV=3 4.68 2805.6 - 976377 - - - 2.6875 - 2.905 0.425 - 428.2 1 2 1 0.0043 13 0 0 0 4.43E+07 3.57E+07 - - - 6.1686 0.9967 221125_WJC_METTL3_EV_vs_WT_F04.15686.15686.2 0.000296 22-Sep R.SAIQVPTDLAQK.F "sp|Q9H082|RB33B_HUMAN,tr|A0A494C0Z5|A0A494C0Z5_HUMAN" 2 1269.6929 1.05 49460 15686 2 1269.696691 635.8537 Ras-related protein Rab-33B OS=Homo sapiens OX=9606 GN=RAB33B PE=1 SV=1 5.55 2805.6 - 756030 - - - 3.0125 - 1.891 0.266 - 210.8 1 2 0 0.0038 12 0 0 0 3.94E+06 3.76E+06 - - - 2.6808 1 221125_WJC_METTL3_EV_vs_WT_F04.15687.15687.2 2.05E-06 15/26 R.LQDTYNLDTDTISK.G sp|P13674|P4HA1_HUMAN 1 1625.7784 1.58 49461 15687 2 1625.781263 813.8965 Prolyl 4-hydroxylase subunit alpha-1 OS=Homo sapiens OX=9606 GN=P4HA1 PE=1 SV=2 3.93 2805.8 - 679260 - - - 1.7321 - 3.255 0.598 - 821.1 1 2 0 0.0028 14 0 0 0 1.05E+08 6.62E+07 - - - 6.4186 0.9994 221125_WJC_METTL3_EV_vs_WT_F04.15688.15688.3 6.66E-06 15/44 R.AEWQVYK[136.11]EEISR[166.11].F "sp|Q00059|TFAM_HUMAN,tr|H7BYN3|H7BYN3_HUMAN" 2 1554.7797 1.08 49462 15688 3 1554.784363 519.2672 "Transcription factor A, mitochondrial OS=Homo sapiens OX=9606 GN=TFAM PE=1 SV=1" 4.79 2805.9 - 597955 - - - 2.9811 - 2.54 0.47 - 381.7 1 2 1 0.0046 12 0 0 0 2.97E+07 2.75E+07 - - - 6.3626 0.9997 221125_WJC_METTL3_EV_vs_WT_F04.15689.15689.3 0.000342 Nov-48 R.ANPQVGVAFPHIK[136.11].H sp|P13010|XRCC5_HUMAN 1 1384.7707 0.93 49463 15689 3 1384.768458 462.5975 X-ray repair cross-complementing protein 5 OS=Homo sapiens OX=9606 GN=XRCC5 PE=1 SV=3 8.8 2806 - 550237 - - - -1.5974 - 1.979 0.377 - 132.2 1 2 0 -0.0022 13 0 0 0 1.14E+07 1.23E+07 - - - 4.5933 0.9999 221125_WJC_METTL3_EV_vs_WT_F04.15690.15690.2 8.53E-05 15/24 K.WAAVVVPSGQEQR[166.11].Y "sp|P10321|HLAC_HUMAN,tr|A0A140T921|A0A140T921_HUMAN,tr|O19617|O19617_HUMAN,tr|Q53Z42|Q53Z42_HUMAN,tr|A0A140T955|A0A140T955_HUMAN,tr|A0A140T913|A0A140T913_HUMAN,tr|A2AEA2|A2AEA2_HUMAN,tr|A0A1W2PPQ2|A0A1W2PPQ2_HUMAN,tr|A0A140T933|A0A140T933_HUMAN,tr|A0A140T9H5|A0A140T9H5_HUMAN,tr|A0A1W2PRT9|A0A1W2PRT9_HUMAN,tr|A0A140T9I0|A0A140T9I0_HUMAN,tr|A0A140T9U8|A0A140T9U8_HUMAN,tr|A0A140T9X5|A0A140T9X5_HUMAN" 14 1435.7447 1.58 49464 15690 2 1435.744409 718.8796 "HLA class I histocompatibility antigen, C alpha chain OS=Homo sapiens OX=9606 GN=HLA-C PE=1 SV=3" 6 2806.2 - 391056 - - - -0.225 - 2.681 0.466 - 820.2 1 2 0 -0.0003 13 0 0 0 4.72E+06 2.98E+06 - - - 5.0139 0.9998 221125_WJC_METTL3_EV_vs_WT_F04.15691.15691.2 9.73E-06 Nov-38 R.SAPAGASEPPPPGGVGLGIR.T "sp|Q8IWZ3|ANKH1_HUMAN,tr|E9PDP5|E9PDP5_HUMAN,tr|D6RHC4|D6RHC4_HUMAN" 3 1785.9373 2.02 49465 15691 2 1785.937382 893.9759 Ankyrin repeat and KH domain-containing protein 1 OS=Homo sapiens OX=9606 GN=ANKHD1 PE=1 SV=1 5.72 2806.3 - 327726 - - - 0.0196 - 1.87 0.487 - 160 1 2 0 0 20 0 0 0 1.67E+06 8.27E+05 - - - 4.1769 0.9904 221125_WJC_METTL3_EV_vs_WT_F04.15692.15692.3 0.0102 Jul-36 K.NLQMWEEMK[136.11]K[136.11].G "sp|P07814|SYEP_HUMAN,tr|V9GYZ6|V9GYZ6_HUMAN" 2 1351.6599 1.8 49466 15692 3 1351.661742 451.5606 Bifunctional glutamate\proline--tRNA ligase OS=Homo sapiens OX=9606 GN=EPRS1 PE=1 SV=5 6.14 2806.4 - 280438 - - - 1.3421 - 1.438 0.215 - 56.2 1 2 0 0.0018 10 0 0 0 4.45E+06 2.48E+06 - - - 1.9974 0.9993 221125_WJC_METTL3_EV_vs_WT_F04.15694.15694.2 0.0221 Aug-38 R.SAPAGASEPPPPGGVGLGIR[166.11].T "sp|Q8IWZ3|ANKH1_HUMAN,tr|E9PDP5|E9PDP5_HUMAN,tr|D6RHC4|D6RHC4_HUMAN" 3 1795.9456 1.9 49468 15694 2 1795.944187 898.9801 Ankyrin repeat and KH domain-containing protein 1 OS=Homo sapiens OX=9606 GN=ANKHD1 PE=1 SV=1 5.72 2806.7 - 182820 - - - -0.7962 - 1.554 0.365 - 55.1 1 2 0 -0.0014 20 0 0 0 2.28E+06 1.20E+06 - - - 2.8202 0.9997 221125_WJC_METTL3_EV_vs_WT_F04.15697.15697.3 0.153 16/52 K.AQIHDLVLVGGSTR[166.11].L "sp|P0DMV8|HS71A_HUMAN,sp|P0DMV9|HS71B_HUMAN,tr|V9GZ37|V9GZ37_HUMAN,tr|A0A0G2JIW1|A0A0G2JIW1_HUMAN" 4 1474.8131 0.2 49470 15697 3 1474.816743 492.6117 Heat shock 70 kDa protein 1A OS=Homo sapiens OX=9606 GN=HSPA1A PE=1 SV=1 6.79 2807.1 - 1.62E+06 - - - 2.439 - 2.494 0.363 - 316.4 1 2 0 0.0036 14 0 0 0 1.73E+07 8.46E+07 - - - 5.0148 0.9999 221125_WJC_METTL3_EV_vs_WT_F04.15698.15698.2 0.000342 13/28 R.AGGADAVQTVTGGLR[166.11].S sp|Q9H223|EHD4_HUMAN 1 1381.7189 1.81 49471 15698 2 1381.719211 691.8667 EH domain-containing protein 4 OS=Homo sapiens OX=9606 GN=EHD4 PE=1 SV=1 5.88 2807.2 - 998650 - - - 0.2164 - 2.721 0.512 - 512.2 1 2 0 0.0003 15 0 0 0 3.84E+07 2.13E+07 - - - 5.2835 1 221125_WJC_METTL3_EV_vs_WT_F04.15699.15699.3 5.43E-08 Dec-64 K.IISNASC[160.03]TTNC[160.03]LAPLAK.V "sp|P04406|G3P_HUMAN,tr|E7EUT5|E7EUT5_HUMAN" 2 1832.9125 1.08 49472 15699 3 1832.914035 611.9781 Glyceraldehyde-3-phosphate dehydrogenase OS=Homo sapiens OX=9606 GN=GAPDH PE=1 SV=3 8.06 2807.2 - 2.66E+07 - - - 0.862 - 2.188 0.638 - 162.6 1 2 0 0.0016 17 0 0 0 1.04E+09 9.61E+08 - - - 7.6307 0.9998 221125_WJC_METTL3_EV_vs_WT_F04.15700.15700.2 0.000306 18-Dec R.RVLQALEGLK.M "sp|P39019|RS19_HUMAN,tr|A0A075B6E2|A0A075B6E2_HUMAN" 2 1125.687 1.11 49473 15700 2 1125.687081 563.8508 40S ribosomal protein S19 OS=Homo sapiens OX=9606 GN=RPS19 PE=1 SV=2 8.75 2807.2 - 2.11E+07 - - - 0.0782 - 2.284 0.391 - 429.9 1 2 0 0.0001 10 0 0 0 2.44E+08 2.19E+08 - - - 4.2343 0.9998 221125_WJC_METTL3_EV_vs_WT_F04.15701.15701.2 0.00177 22-Nov K.YQEVTNNLEFAK[136.11].E "sp|Q14444|CAPR1_HUMAN,tr|G3V153|G3V153_HUMAN,tr|E9PLA9|E9PLA9_HUMAN" 3 1462.7184 0.88 49474 15701 2 1462.716049 732.3665 Caprin-1 OS=Homo sapiens OX=9606 GN=CAPRIN1 PE=1 SV=2 4.53 2807.3 - 5.26E+06 - - - -1.5793 - 2.243 0.506 - 262.3 1 2 0 -0.0023 12 0 0 0 8.35E+07 9.51E+07 - - - 4.9031 0.9999 221125_WJC_METTL3_EV_vs_WT_F04.15702.15702.2 0.000292 22-Dec K.YQEVTNNLEFAK.E "sp|Q14444|CAPR1_HUMAN,tr|G3V153|G3V153_HUMAN,tr|E9PLA9|E9PLA9_HUMAN" 3 1454.7042 0.89 49475 15702 2 1454.704357 728.3594 Caprin-1 OS=Homo sapiens OX=9606 GN=CAPRIN1 PE=1 SV=2 4.53 2807.3 - 4.80E+06 - - - 0.1361 - 2.47 0.533 - 342.7 1 2 0 0.0002 12 0 0 0 8.35E+07 9.40E+07 - - - 5.3568 1 221125_WJC_METTL3_EV_vs_WT_F04.15703.15703.2 1.42E-07 13/24 R.VGIQQGLLSQSTR[166.11].T "sp|Q9BY77|PDIP3_HUMAN,tr|F6VRR5|F6VRR5_HUMAN,tr|F8WCX5|F8WCX5_HUMAN,tr|Q6R954|Q6R954_HUMAN,tr|Q8WUT1|Q8WUT1_HUMAN,tr|F8WEE2|F8WEE2_HUMAN" 6 1395.7709 1.34 49476 15703 2 1395.770897 698.8927 Polymerase delta-interacting protein 3 OS=Homo sapiens OX=9606 GN=POLDIP3 PE=1 SV=2 9.72 2807.4 - 4.00E+06 - - - -0.0358 - 2.821 0.548 - 672.5 1 2 0 -0.0001 13 0 0 0 8.11E+07 6.05E+07 - - - 5.7502 1 221125_WJC_METTL3_EV_vs_WT_F04.15704.15704.3 1.29E-09 16/56 R.GPSLNPVLDYDHGSR.S "sp|P43243|MATR3_HUMAN,tr|A8MXP9|A8MXP9_HUMAN,tr|D6R991|D6R991_HUMAN,tr|A0A0R4J2E8|A0A0R4J2E8_HUMAN,tr|D6REM6|D6REM6_HUMAN" 5 1625.7798 1.02 49477 15704 3 1625.780056 542.9339 Matrin-3 OS=Homo sapiens OX=9606 GN=MATR3 PE=1 SV=2 5.21 2807.4 - 2.93E+06 - - - 0.1673 - 3.222 0.656 - 389.9 1 2 0 0.0003 15 0 0 0 2.55E+07 2.51E+07 - - - 8.9066 0.9982 221125_WJC_METTL3_EV_vs_WT_F04.15705.15705.3 0.00137 Aug-36 R.LVNHFVEEFK[136.11].R "sp|P0DMV8|HS71A_HUMAN,sp|P0DMV9|HS71B_HUMAN,tr|V9GZ37|V9GZ37_HUMAN,tr|A0A0G2JIW1|A0A0G2JIW1_HUMAN" 4 1268.6645 0.13 49478 15705 3 1268.663583 423.8954 Heat shock 70 kDa protein 1A OS=Homo sapiens OX=9606 GN=HSPA1A PE=1 SV=1 5.4 2807.5 - 2.74E+06 - - - -0.7015 - 1.897 0.222 - 119 1 2 0 -0.0009 10 0 0 0 2.65E+07 2.08E+08 - - - 2.8847 1 221125_WJC_METTL3_EV_vs_WT_F04.15707.15707.2 2.11E-05 17/26 R.LQDTYNLDTDTISK[136.11].G sp|P13674|P4HA1_HUMAN 1 1633.7926 1.58 49480 15707 2 1633.792068 817.9036 Prolyl 4-hydroxylase subunit alpha-1 OS=Homo sapiens OX=9606 GN=P4HA1 PE=1 SV=2 3.93 2807.6 - 2.13E+06 - - - -0.3544 - 3.243 0.572 - 1259.4 1 2 0 -0.0006 14 0 0 0 1.05E+08 6.62E+07 - - - 6.218 1 221125_WJC_METTL3_EV_vs_WT_F04.15715.15715.3 3.29E-11 20/56 K.GVTIVK[136.11]PIVYGNVAR[166.11].Y "sp|O95619|YETS4_HUMAN,tr|F8W1B9|F8W1B9_HUMAN,tr|F8W0J4|F8W0J4_HUMAN" 3 1602.9576 1.23 49488 15715 3 1602.960953 535.3265 YEATS domain-containing protein 4 OS=Homo sapiens OX=9606 GN=YEATS4 PE=1 SV=1 9.99 2808.2 - 1.04E+06 - - - 2.0718 - 3.565 0.667 - 431.8 1 2 0 0.0033 15 0 0 0 1.25E+07 1.01E+07 - - - 9.2924 0.9998 221125_WJC_METTL3_EV_vs_WT_F04.15716.15716.2 3.19E-06 14/24 K.WAAVVVPSGQEQR.Y "sp|P10321|HLAC_HUMAN,tr|A0A140T921|A0A140T921_HUMAN,tr|O19617|O19617_HUMAN,tr|Q53Z42|Q53Z42_HUMAN,tr|A0A140T955|A0A140T955_HUMAN,tr|A0A140T913|A0A140T913_HUMAN,tr|A2AEA2|A2AEA2_HUMAN,tr|A0A1W2PPQ2|A0A1W2PPQ2_HUMAN,tr|A0A140T933|A0A140T933_HUMAN,tr|A0A140T9H5|A0A140T9H5_HUMAN,tr|A0A1W2PRT9|A0A1W2PRT9_HUMAN,tr|A0A140T9I0|A0A140T9I0_HUMAN,tr|A0A140T9U8|A0A140T9U8_HUMAN,tr|A0A140T9X5|A0A140T9X5_HUMAN" 14 1425.7365 1.58 49489 15716 2 1425.738285 713.8755 "HLA class I histocompatibility antigen, C alpha chain OS=Homo sapiens OX=9606 GN=HLA-C PE=1 SV=3" 6 2808.4 - 831364 - - - 1.2786 - 2.692 0.487 - 577.8 1 2 0 0.0018 13 0 0 0 4.72E+06 2.98E+06 - - - 5.179 1 221125_WJC_METTL3_EV_vs_WT_F04.15718.15718.2 3.06E-09 13/24 R.SGNTGIATTFINK[136.11].A sp|Q9UJV9|DDX41_HUMAN 1 1330.6972 1.16 49490 15718 2 1330.696784 666.3559 Probable ATP-dependent RNA helicase DDX41 OS=Homo sapiens OX=9606 GN=DDX41 PE=1 SV=2 8.47 2808.6 - 3.65E+06 - - - -0.3352 - 2.894 0.623 - 784.1 1 2 0 -0.0004 13 0 0 0 4.31E+07 3.73E+07 - - - 6.3696 0.9999 221125_WJC_METTL3_EV_vs_WT_F04.15719.15719.3 1.40E-05 15/44 R.AEWQVYKEEISR.F "sp|Q00059|TFAM_HUMAN,tr|H7BYN3|H7BYN3_HUMAN" 2 1536.7573 1.08 49491 15719 3 1536.756656 513.2597 "Transcription factor A, mitochondrial OS=Homo sapiens OX=9606 GN=TFAM PE=1 SV=1" 4.79 2808.6 - 2.60E+06 - - - -0.3911 - 2.647 0.463 - 349.9 1 2 1 -0.0006 12 0 0 0 2.97E+07 2.75E+07 - - - 6.4 0.9996 221125_WJC_METTL3_EV_vs_WT_F04.15720.15720.3 2.82E-06 18/48 K.LQEELDK[136.11]YSQALR[166.11].K "sp|Q15643|TRIPB_HUMAN,tr|H0YJ97|H0YJ97_HUMAN" 2 1609.8431 1.24 49492 15720 3 1609.842866 537.6216 Thyroid receptor-interacting protein 11 OS=Homo sapiens OX=9606 GN=TRIP11 PE=1 SV=3 4.68 2808.7 - 4.92E+06 - - - -0.118 - 2.921 0.353 - 708.6 1 2 1 -0.0002 13 0 0 0 4.43E+07 3.57E+07 - - - 5.3819 0.9999 221125_WJC_METTL3_EV_vs_WT_F04.15721.15721.3 3.41E-06 14/44 R.YMVADK[136.11]FTELQK[136.11].A "sp|P30153|2AAA_HUMAN,tr|C9J9C1|C9J9C1_HUMAN,tr|B3KQV6|B3KQV6_HUMAN" 3 1487.7665 2.84 49493 15721 3 1487.765431 496.9294 Serine\threonine-protein phosphatase 2A 65 kDa regulatory subunit A alpha isoform OS=Homo sapiens OX=9606 GN=PPP2R1A PE=1 SV=4 6.07 2808.7 - 1.73E+06 - - - -0.7199 - 2.565 0.572 - 208.3 1 2 1 -0.0011 12 0 0 0 2.49E+07 8.75E+06 - - - 7.5279 1 221125_WJC_METTL3_EV_vs_WT_F04.15722.15722.3 2.45E-08 18/56 K.GVTIVKPIVYGNVAR.Y "sp|O95619|YETS4_HUMAN,tr|F8W1B9|F8W1B9_HUMAN,tr|F8W0J4|F8W0J4_HUMAN" 3 1584.9352 1.24 49494 15722 3 1584.934802 529.319 YEATS domain-containing protein 4 OS=Homo sapiens OX=9606 GN=YEATS4 PE=1 SV=1 9.99 2808.8 - 1.73E+06 - - - -0.2271 - 3.339 0.607 - 348.5 1 2 0 -0.0004 15 0 0 0 1.26E+07 1.01E+07 - - - 8.4534 0.9976 221125_WJC_METTL3_EV_vs_WT_F04.15724.15724.3 0.000747 14/52 K.FASTVFPSDHIPSR[166.11].Y "sp|Q5VYK3|ECM29_HUMAN,tr|J3KN16|J3KN16_HUMAN,tr|A0A804HJA4|A0A804HJA4_HUMAN,tr|R4GMY1|R4GMY1_HUMAN" 4 1569.7815 0.39 49496 15724 3 1569.776226 524.2678 Proteasome adapter and scaffold protein ECM29 OS=Homo sapiens OX=9606 GN=ECPAS PE=1 SV=2 6.74 2809.1 - 1.09E+06 - - - -3.3673 - 2.65 0.243 - 159.9 1 2 0 -0.0053 14 0 0 0 5.88E+06 1.53E+07 - - - 3.8377 0.9999 221125_WJC_METTL3_EV_vs_WT_F04.15725.15725.2 0.000345 24-Dec K.DGTSPEEEIEIER[166.11].Q sp|Q9H501|ESF1_HUMAN 1 1512.6819 1.82 49497 15725 2 1512.683477 757.3482 ESF1 homolog OS=Homo sapiens OX=9606 GN=ESF1 PE=1 SV=1 3.83 2809.2 - 1.08E+06 - - - 1.0313 - 2.313 0.517 - 477.2 1 2 0 0.0016 13 0 0 0 5.36E+07 2.94E+07 - - - 5.0112 0.9996 221125_WJC_METTL3_EV_vs_WT_F04.15727.15727.3 0.00673 Oct-36 R.LVNHFVEEFK.R "sp|P0DMV8|HS71A_HUMAN,sp|P0DMV9|HS71B_HUMAN,tr|V9GZ37|V9GZ37_HUMAN,tr|A0A0G2JIW1|A0A0G2JIW1_HUMAN" 4 1260.6503 0.13 49499 15727 3 1260.647907 421.224 Heat shock 70 kDa protein 1A OS=Homo sapiens OX=9606 GN=HSPA1A PE=1 SV=1 5.4 2809.4 - 796181 - - - -1.8768 - 1.906 0.352 - 148.2 1 2 0 -0.0024 10 0 0 0 2.65E+07 2.07E+08 - - - 4.3475 0.9999 221125_WJC_METTL3_EV_vs_WT_F04.15728.15728.3 1.58E-05 13/48 R.ANPQVGVAFPHIK.H sp|P13010|XRCC5_HUMAN 1 1376.7565 0.84 49500 15728 3 1376.754553 459.9261 X-ray repair cross-complementing protein 5 OS=Homo sapiens OX=9606 GN=XRCC5 PE=1 SV=3 8.8 2809.5 - 793293 - - - -1.3924 - 2.167 0.48 - 204.4 1 2 0 -0.0019 13 0 0 0 7.96E+06 9.46E+06 - - - 5.9878 0.9986 221125_WJC_METTL3_EV_vs_WT_F04.15731.15731.3 0.036 Oct-36 K.K[136.11]SEEEIDFLR[166.11].S "sp|Q9Y262|EIF3L_HUMAN,tr|B0QY89|B0QY89_HUMAN,tr|B0QY90|B0QY90_HUMAN" 3 1282.6524 1.14 49503 15731 3 1282.651957 428.5581 Eukaryotic translation initiation factor 3 subunit L OS=Homo sapiens OX=9606 GN=EIF3L PE=1 SV=1 4.41 2809.9 - 677130 - - - -0.3469 - 1.769 0.255 - 146.2 1 2 0 -0.0004 10 0 0 0 3.63E+06 3.19E+06 - - - 3.0487 0.9929 221125_WJC_METTL3_EV_vs_WT_F04.15736.15736.2 0.00363 24-Dec K.LQEELDK[136.11]YSQALR[166.11].K "sp|Q15643|TRIPB_HUMAN,tr|H0YJ97|H0YJ97_HUMAN" 2 1609.8431 -1 49508 15736 2 1609.839123 805.9288 Thyroid receptor-interacting protein 11 OS=Homo sapiens OX=9606 GN=TRIP11 PE=1 SV=3 4.68 2810.6 - 292410 - - - -2.4431 - 2.531 0.346 - 514.9 1 2 1 -0.0039 13 0 0 0 0.00E+00 0.00E+00 - - - 3.9786 1 221125_WJC_METTL3_EV_vs_WT_F04.15739.15739.3 0.000159 14/44 R.QWVAAGGHITFK[136.11].Q sp|Q9NTZ6|RBM12_HUMAN 1 1321.7023 0.8 49510 15739 3 1321.70217 441.5747 RNA-binding protein 12 OS=Homo sapiens OX=9606 GN=RBM12 PE=1 SV=1 8.76 2810.9 - 1.17E+06 - - - -0.0651 - 2.556 0.474 - 306.3 1 2 0 -0.0001 12 0 0 0 8.45E+06 1.05E+07 - - - 6.4258 0.9999 221125_WJC_METTL3_EV_vs_WT_F04.15742.15742.3 0.000239 14/44 R.QWVAAGGHITFK.Q sp|Q9NTZ6|RBM12_HUMAN 1 1313.6881 0.66 49513 15742 3 1313.686619 438.9033 RNA-binding protein 12 OS=Homo sapiens OX=9606 GN=RBM12 PE=1 SV=1 8.76 2811.3 - 1.18E+06 - - - -1.0939 - 2.66 0.362 - 320.9 1 2 0 -0.0014 12 0 0 0 8.55E+06 1.30E+07 - - - 5.2873 0.9999 221125_WJC_METTL3_EV_vs_WT_F04.15743.15743.3 0.0179 Dec-52 R.FDHIFYTGNTAVGK[136.11].L "sp|P51648|AL3A2_HUMAN,tr|I3L1M4|I3L1M4_HUMAN,tr|A0A5F9ZHI5|A0A5F9ZHI5_HUMAN,tr|A0A5F9ZI12|A0A5F9ZI12_HUMAN,tr|A0A5F9ZHZ9|A0A5F9ZHZ9_HUMAN,tr|A0A5F9ZHN9|A0A5F9ZHN9_HUMAN,tr|A0A5F9ZGX4|A0A5F9ZGX4_HUMAN,tr|J3QRD1|J3QRD1_HUMAN" 8 1576.7765 0.98 49514 15743 3 1576.773916 526.5995 Aldehyde dehydrogenase family 3 member A2 OS=Homo sapiens OX=9606 GN=ALDH3A2 PE=1 SV=1 6.74 2811.4 - 995823 - - - -1.6661 - 1.971 0.441 - 141.2 1 2 0 -0.0026 14 0 0 0 9.51E+06 9.69E+06 - - - 5.2592 1 221125_WJC_METTL3_EV_vs_WT_F04.15745.15745.3 0.000106 19/52 K.GIRPAINVGLSVSR.V sp|P25705|ATPA_HUMAN 1 1437.8416 1.34 49516 15745 3 1437.840006 480.2878 "ATP synthase subunit alpha, mitochondrial OS=Homo sapiens OX=9606 GN=ATP5F1A PE=1 SV=1" 12 2811.6 - 835145 - - - -1.1058 - 3.413 0.46 - 643.4 1 2 0 -0.0016 14 0 0 0 1.04E+08 7.75E+07 - - - 6.9305 0.9998 221125_WJC_METTL3_EV_vs_WT_F04.15746.15746.3 0.00171 Nov-48 R.HLFGQPNSAYDFK.T "sp|O95347|SMC2_HUMAN,tr|A0A0C4DGE5|A0A0C4DGE5_HUMAN" 2 1522.7205 0.64 49517 15746 3 1522.719305 508.5808 Structural maintenance of chromosomes protein 2 OS=Homo sapiens OX=9606 GN=SMC2 PE=1 SV=2 6.74 2811.8 - 459426 - - - -0.7703 - 1.932 0.387 - 104.7 1 2 0 -0.0012 13 0 0 0 7.44E+06 1.17E+07 - - - 4.6399 0.9926 221125_WJC_METTL3_EV_vs_WT_F04.15747.15747.3 0.116 Aug-40 R.VGDLILAHLHK.K "sp|Q53GS7|GLE1_HUMAN,tr|A0A804HJ00|A0A804HJ00_HUMAN,tr|A0A804HK09|A0A804HK09_HUMAN,tr|A0A804HJB3|A0A804HJB3_HUMAN,tr|A0A804HJY9|A0A804HJY9_HUMAN,tr|A0A804HJ70|A0A804HJ70_HUMAN" 6 1214.7135 6.69 49518 15747 3 1214.711468 405.9118 mRNA export factor GLE1 OS=Homo sapiens OX=9606 GN=GLE1 PE=1 SV=2 6.89 2811.9 - 334345 - - - -1.7074 - 1.703 0.196 - 55.3 1 2 0 -0.0021 11 0 0 0 2.64E+06 3.95E+05 - - - 2.2371 0.9829 221125_WJC_METTL3_EV_vs_WT_F04.15750.15750.2 2.03E-05 22-Dec A.TQSLSMPASLGR.M "sp|P43243|MATR3_HUMAN,tr|A0A1B0GX04|A0A1B0GX04_HUMAN,tr|D6RBS2|D6RBS2_HUMAN,tr|A8MXP9|A8MXP9_HUMAN,tr|D6R991|D6R991_HUMAN,tr|D6REK4|D6REK4_HUMAN,tr|D6R9F3|D6R9F3_HUMAN,tr|A0A0R4J2E8|A0A0R4J2E8_HUMAN,tr|D6RB45|D6RB45_HUMAN,tr|D6RCM3|D6RCM3_HUMAN,tr|D6R8Z5|D6R8Z5_HUMAN,tr|D6REM6|D6REM6_HUMAN" 12 1246.634 1.26 49519 15750 2 1246.631226 624.3243 Matrin-3 OS=Homo sapiens OX=9606 GN=MATR3 PE=1 SV=2 9.41 2812.3 - 1.02E+07 - - - -2.2019 - 2.219 0.513 - 636.8 1 1 0 -0.0027 12 0 0 0 7.70E+07 6.13E+07 - - - 4.9263 1 221125_WJC_METTL3_EV_vs_WT_F04.15752.15752.3 6.11E-10 17/52 K.GIR[166.11]PAINVGLSVSR[166.11].V sp|P25705|ATPA_HUMAN 1 1457.8581 1.34 49521 15752 3 1457.856135 486.96 "ATP synthase subunit alpha, mitochondrial OS=Homo sapiens OX=9606 GN=ATP5F1A PE=1 SV=1" 12 2812.4 - 2.66E+06 - - - -1.3726 - 3.446 0.543 - 470.4 1 2 0 -0.002 14 0 0 0 1.04E+08 7.75E+07 - - - 7.8813 0.9996 221125_WJC_METTL3_EV_vs_WT_F04.15755.15755.3 0.00347 13/36 R.K[136.11]AAALEFLNR[166.11].F "sp|P31948|STIP1_HUMAN,tr|F5GXD8|F5GXD8_HUMAN,tr|F5H783|F5H783_HUMAN" 3 1149.6625 0.001 49524 15755 3 1149.659534 384.2281 Stress-induced-phosphoprotein 1 OS=Homo sapiens OX=9606 GN=STIP1 PE=1 SV=1 8.75 2812.7 - 849583 - - - -2.5912 - 2.095 0.37 - 293.9 1 2 0 -0.003 10 0 0 0 0.00E+00 6.98E+06 - - - 4.8241 0.8843 221125_WJC_METTL3_EV_vs_WT_F04.15756.15756.2 0.453 18-Oct E.QLAQSLSLTK[136.11].Y "tr|A0A0G2JN65|A0A0G2JN65_HUMAN,tr|H0Y5X7|H0Y5X7_HUMAN" 2 1095.6379 0.001 49525 15756 2 1095.638139 548.8262 CCR4-NOT transcription complex subunit 3 (Fragment) OS=Homo sapiens OX=9606 GN=CNOT3 PE=1 SV=1 8.75 2812.8 - 662034 - - - 0.1962 - 1.669 0.172 - 219.2 1 1 0 0.0002 10 0 0 0 0.00E+00 8.38E+06 - - - 1.7411 0.9986 221125_WJC_METTL3_EV_vs_WT_F04.15757.15757.3 0.0133 Aug-40 R.NYAHALDGLYR.V "sp|Q9UBX3|DIC_HUMAN,tr|F6RGN5|F6RGN5_HUMAN,tr|B4DLN1|B4DLN1_HUMAN" 3 1291.6309 1.28 49526 15757 3 1291.631948 431.5509 Mitochondrial dicarboxylate carrier OS=Homo sapiens OX=9606 GN=SLC25A10 PE=1 SV=2 6.74 2812.9 - 613579 - - - 0.7843 - 1.605 0.287 - 77.6 1 2 0 0.001 11 0 0 0 4.69E+06 3.66E+06 - - - 3.0835 0.998 221125_WJC_METTL3_EV_vs_WT_F04.15759.15759.3 0.00697 Oct-40 R.NYAHALDGLYR[166.11].V "sp|Q9UBX3|DIC_HUMAN,tr|F6RGN5|F6RGN5_HUMAN,tr|B4DLN1|B4DLN1_HUMAN" 3 1301.6392 1.34 49528 15759 3 1301.635415 434.887 Mitochondrial dicarboxylate carrier OS=Homo sapiens OX=9606 GN=SLC25A10 PE=1 SV=2 6.74 2813.2 - 567847 - - - -2.9117 - 1.568 0.351 - 128.5 1 2 0 -0.0038 11 0 0 0 4.69E+06 3.50E+06 - - - 3.7301 1 221125_WJC_METTL3_EV_vs_WT_F04.15760.15760.2 1.88E-06 20-Dec K.QQVADEDEIWK[136.11].Q "sp|Q9Y520|PRC2C_HUMAN,tr|A0A0A0MS30|A0A0A0MS30_HUMAN,tr|E7EPN9|E7EPN9_HUMAN" 3 1367.6449 1.31 49529 15760 2 1367.641161 684.8297 Protein PRRC2C OS=Homo sapiens OX=9606 GN=PRRC2C PE=1 SV=4 3.92 2813.3 - 560410 - - - -2.7046 - 2.489 0.583 - 632.4 1 2 0 -0.0037 11 0 0 0 3.48E+07 2.65E+07 - - - 5.8127 1 221125_WJC_METTL3_EV_vs_WT_F04.15763.15763.2 2.52E-09 14/18 R.LVNHFVEEFK[136.11].R "sp|P0DMV8|HS71A_HUMAN,sp|P0DMV9|HS71B_HUMAN,tr|V9GZ37|V9GZ37_HUMAN,tr|A0A0G2JIW1|A0A0G2JIW1_HUMAN" 4 1268.6645 0.17 49531 15763 2 1268.662577 635.3395 Heat shock 70 kDa protein 1A OS=Homo sapiens OX=9606 GN=HSPA1A PE=1 SV=1 5.4 2813.7 - 8.04E+06 - - - -1.4945 - 3.046 0.657 - 1030.4 1 2 0 -0.0019 10 0 0 0 1.23E+07 7.13E+07 - - - 7.002 0.9996 221125_WJC_METTL3_EV_vs_WT_F04.15766.15766.3 2.43E-06 Dec-56 R.GPSLNPVLDYDHGSR[166.11].S "sp|P43243|MATR3_HUMAN,tr|A8MXP9|A8MXP9_HUMAN,tr|D6R991|D6R991_HUMAN,tr|A0A0R4J2E8|A0A0R4J2E8_HUMAN,tr|D6REM6|D6REM6_HUMAN" 5 1635.7881 1.02 49534 15766 3 1635.782809 546.27 Matrin-3 OS=Homo sapiens OX=9606 GN=MATR3 PE=1 SV=2 5.21 2813.9 - 2.10E+06 - - - -3.2064 - 2.562 0.377 - 172.6 1 2 0 -0.0052 15 0 0 0 2.58E+07 2.53E+07 - - - 5.1966 0.7715 221125_WJC_METTL3_EV_vs_WT_F04.15767.15767.3 0.0724 Nov-32 R.YKMLDQRIK.M "sp|Q14123|PDE1C_HUMAN,tr|A0A0A0MS69|A0A0A0MS69_HUMAN" 2 1193.6591 15.36 49535 15767 3 1193.650735 398.8936 "Calcium\calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1C OS=Homo sapiens OX=9606 GN=PDE1C PE=1 SV=1" 9.7 2814 - 1.79E+06 - - - -6.9777 - 1.907 0.252 - 184.7 1 2 2 -0.0083 9 0 0 0 4.83E+07 3.14E+06 - - - 3.2927 1 221125_WJC_METTL3_EV_vs_WT_F04.15768.15768.2 3.29E-07 20-Dec K.QQVADEDEIWK.Q "sp|Q9Y520|PRC2C_HUMAN,tr|A0A0A0MS30|A0A0A0MS30_HUMAN,tr|E7EPN9|E7EPN9_HUMAN" 3 1359.6307 1.31 49536 15768 2 1359.629594 680.8226 Protein PRRC2C OS=Homo sapiens OX=9606 GN=PRRC2C PE=1 SV=4 3.92 2814.1 - 1.26E+06 - - - -0.784 - 2.42 0.593 - 629 1 2 0 -0.0011 11 0 0 0 3.48E+07 2.65E+07 - - - 5.8114 1 221125_WJC_METTL3_EV_vs_WT_F04.15769.15769.2 1.32E-07 16/30 N.TLAVNAAQDSTDLVAK.L "sp|P17987|TCPA_HUMAN,tr|F5H282|F5H282_HUMAN,tr|E7EQR6|E7EQR6_HUMAN" 3 1615.8417 0.49 49537 15769 2 1615.840339 808.9281 T-complex protein 1 subunit alpha OS=Homo sapiens OX=9606 GN=TCP1 PE=1 SV=1 4.21 2814.3 - 1.03E+06 - - - -0.8516 - 2.95 0.573 - 725.7 1 1 0 -0.0014 16 0 0 0 2.58E+07 5.22E+07 - - - 5.9324 0.9964 221125_WJC_METTL3_EV_vs_WT_F04.15770.15770.3 0.00428 Sep-32 R.K[136.11]LQFFC[160.03]DPR[166.11].K "sp|Q53H12|AGK_HUMAN,tr|E9PC15|E9PC15_HUMAN,tr|A0A3B3ITD0|A0A3B3ITD0_HUMAN,tr|A0A3B3ISY9|A0A3B3ISY9_HUMAN,tr|A0A0G2JLG5|A0A0G2JLG5_HUMAN" 5 1227.6189 0.77 49538 15770 3 1227.615738 410.2136 "Acylglycerol kinase, mitochondrial OS=Homo sapiens OX=9606 GN=AGK PE=1 SV=2" 8.22 2814.4 - 519886 - - - -2.6034 - 1.516 0.3 - 108.4 1 2 0 -0.0032 9 0 0 0 4.95E+06 6.45E+06 - - - 3.1378 1 221125_WJC_METTL3_EV_vs_WT_F04.15773.15773.2 1.41E-10 15/24 R.QFMAETQFTSGEK[136.11].E "sp|Q14444|CAPR1_HUMAN,tr|G3V153|G3V153_HUMAN" 2 1510.6853 1.07 49539 15773 2 1510.683308 756.3499 Caprin-1 OS=Homo sapiens OX=9606 GN=CAPRIN1 PE=1 SV=2 4.53 2814.8 - 3.07E+06 - - - -1.3484 - 2.705 0.691 - 987.3 1 2 0 -0.002 13 0 0 0 5.32E+07 4.96E+07 - - - 6.698 0.9986 221125_WJC_METTL3_EV_vs_WT_F04.15776.15776.3 0.0123 Aug-40 R.YQLLQLR[166.11]PAQR[166.11].A "sp|Q9BXJ9|NAA15_HUMAN,tr|A0A0B4J1W3|A0A0B4J1W3_HUMAN" 2 1404.8105 0.05 49542 15776 3 1404.809282 469.2774 "N-alpha-acetyltransferase 15, NatA auxiliary subunit OS=Homo sapiens OX=9606 GN=NAA15 PE=1 SV=1" 10.84 2814.9 - 1.59E+06 - - - -0.8371 - 1.569 0.292 - 67.6 1 2 0 -0.0012 11 0 0 0 9.02E+05 1.87E+07 - - - 3.0748 0.9999 221125_WJC_METTL3_EV_vs_WT_F04.15778.15778.3 1.19E-05 16/48 K.YGK[136.11]IETIEVMEDR[166.11].Q "sp|P51991|ROA3_HUMAN,tr|A0A7I2V5D8|A0A7I2V5D8_HUMAN,tr|A0A7I2V2R3|A0A7I2V2R3_HUMAN,tr|A0A7I2V4J6|A0A7I2V4J6_HUMAN,tr|A0A7I2V4G0|A0A7I2V4G0_HUMAN,tr|A0A7I2V402|A0A7I2V402_HUMAN" 6 1599.7933 1.76 49544 15778 3 1599.790673 534.2717 Heterogeneous nuclear ribonucleoprotein A3 OS=Homo sapiens OX=9606 GN=HNRNPA3 PE=1 SV=2 4.41 2815.2 - 1.05E+06 - - - -1.6602 - 3.215 0.521 - 463.2 1 2 1 -0.0027 13 0 0 0 1.97E+07 1.12E+07 - - - 7.5142 0.9999 221125_WJC_METTL3_EV_vs_WT_F04.15779.15779.3 4.30E-07 14/44 K.GAHTTMADALWR.L sp|Q86U86|PB1_HUMAN 1 1328.6296 1.38 49545 15779 3 1328.628339 443.8838 Protein polybromo-1 OS=Homo sapiens OX=9606 GN=PBRM1 PE=1 SV=1 6.74 2815.3 - 999056 - - - -0.9145 - 2.521 0.427 - 359.7 1 2 0 -0.0012 12 0 0 0 1.42E+07 1.03E+07 - - - 5.8633 0.7699 221125_WJC_METTL3_EV_vs_WT_F04.15781.15781.3 0.0735 Sep-68 R.LVLGTHTSDEQNHLVIAS.V "sp|Q09028|RBBP4_HUMAN,tr|E9PND5|E9PND5_HUMAN,tr|C9JPP3|C9JPP3_HUMAN,tr|E9PNS6|E9PNS6_HUMAN" 4 1932.9905 - 49547 15781 3 1932.986035 645.3374 Histone-binding protein RBBP4 OS=Homo sapiens OX=9606 GN=RBBP4 PE=1 SV=3 5.15 2815.6 - 740804 - - - -2.3125 - 1.641 0.303 - 55.4 1 1 0 -0.0045 18 0 0 0 - - - - - 3.1503 0.9998 221125_WJC_METTL3_EV_vs_WT_F04.15783.15783.3 0.00339 Oct-40 R.K[136.11]LVIIEGDLER[166.11].T "sp|P06753|TPM3_HUMAN,tr|A0A2R2Y2Q3|A0A2R2Y2Q3_HUMAN,tr|A0A087WWU8|A0A087WWU8_HUMAN,tr|J3KN67|J3KN67_HUMAN,tr|A0A494C0P6|A0A494C0P6_HUMAN" 5 1301.7674 1.32 49549 15783 3 1301.766819 434.9297 Tropomyosin alpha-3 chain OS=Homo sapiens OX=9606 GN=TPM3 PE=1 SV=2 4.68 2815.8 - 644519 - - - -0.4248 - 2.094 0.352 - 236.6 1 2 0 -0.0006 11 0 0 0 5.01E+06 3.79E+06 - - - 4.5639 0.9992 221125_WJC_METTL3_EV_vs_WT_F04.15784.15784.3 2.70E-05 Oct-44 K.GAHTTMADALWR[166.11].L sp|Q86U86|PB1_HUMAN 1 1338.6378 1.45 49550 15784 3 1338.632419 447.2199 Protein polybromo-1 OS=Homo sapiens OX=9606 GN=PBRM1 PE=1 SV=1 6.74 2815.9 - 581375 - - - -4.0377 - 2.23 0.403 - 159.4 1 2 0 -0.0054 12 0 0 0 1.54E+07 1.07E+07 - - - 5.2546 0.9894 221125_WJC_METTL3_EV_vs_WT_F04.15786.15786.3 0.0342 Oct-44 K.YPVYGVQWHPEK.A "sp|Q92820|GGH_HUMAN,tr|A0A7I2YQQ3|A0A7I2YQQ3_HUMAN" 2 1501.7354 11.73 49552 15786 3 1501.735293 501.5857 Gamma-glutamyl hydrolase OS=Homo sapiens OX=9606 GN=GGH PE=1 SV=2 6.75 2816.2 - 380562 - - - -0.0713 - 1.632 0.168 - 84.3 1 2 0 -0.0001 12 0 0 0 4.20E+06 3.58E+05 - - - 1.7707 1 221125_WJC_METTL3_EV_vs_WT_F04.15789.15789.2 4.41E-12 15/32 K.IISNASC[160.03]TTNC[160.03]LAPLAK.V "sp|P04406|G3P_HUMAN,tr|E7EUT5|E7EUT5_HUMAN" 2 1832.9125 1.05 49554 15789 2 1832.9115 917.4635 Glyceraldehyde-3-phosphate dehydrogenase OS=Homo sapiens OX=9606 GN=GAPDH PE=1 SV=3 8.06 2816.6 - 4.47E+07 - - - -0.521 - 3.433 0.701 - 492.3 1 2 0 -0.001 17 0 0 0 1.34E+09 1.27E+09 - - - 7.2507 1 221125_WJC_METTL3_EV_vs_WT_F04.15790.15790.2 4.08E-10 13/24 R.QFMAETQFTSGEK.E "sp|Q14444|CAPR1_HUMAN,tr|G3V153|G3V153_HUMAN" 2 1502.6711 1.08 49555 15790 2 1502.671032 752.3428 Caprin-1 OS=Homo sapiens OX=9606 GN=CAPRIN1 PE=1 SV=2 4.53 2816.6 - 3.97E+06 - - - -0.0752 - 2.719 0.695 - 768.9 1 2 0 -0.0001 13 0 0 0 5.40E+07 5.00E+07 - - - 6.7414 1 221125_WJC_METTL3_EV_vs_WT_F04.15791.15791.2 3.29E-07 14/30 N.TLAVNAAQDSTDLVAK[136.11].L "sp|P17987|TCPA_HUMAN,tr|F5H282|F5H282_HUMAN,tr|E7EQR6|E7EQR6_HUMAN" 3 1623.8559 0.49 49556 15791 2 1623.853961 812.9352 T-complex protein 1 subunit alpha OS=Homo sapiens OX=9606 GN=TCP1 PE=1 SV=1 4.21 2816.7 - 4.45E+06 - - - -1.2033 - 2.906 0.591 - 511.9 1 1 0 -0.002 16 0 0 0 2.58E+07 5.22E+07 - - - 6.0282 0.9974 221125_WJC_METTL3_EV_vs_WT_F04.15793.15793.3 1.96E-07 14/60 N.TLAVNAAQDSTDLVAK[136.11].L "sp|P17987|TCPA_HUMAN,tr|F5H282|F5H282_HUMAN,tr|E7EQR6|E7EQR6_HUMAN" 3 1623.8559 0.41 49558 15793 3 1623.857709 542.2926 T-complex protein 1 subunit alpha OS=Homo sapiens OX=9606 GN=TCP1 PE=1 SV=1 4.21 2816.9 - 1.24E+06 - - - 1.1048 - 2.492 0.546 - 201.4 1 1 0 0.0018 16 0 0 0 4.33E+06 1.06E+07 - - - 6.9697 0.9999 221125_WJC_METTL3_EV_vs_WT_F04.15795.15795.3 2.63E-09 17/48 K.YGKIETIEVMEDR.Q "sp|P51991|ROA3_HUMAN,tr|A0A7I2V5D8|A0A7I2V5D8_HUMAN,tr|A0A7I2V2R3|A0A7I2V2R3_HUMAN,tr|A0A7I2V4J6|A0A7I2V4J6_HUMAN,tr|A0A7I2V4G0|A0A7I2V4G0_HUMAN,tr|A0A7I2V402|A0A7I2V402_HUMAN" 6 1581.7709 1.76 49560 15795 3 1581.772619 528.2642 Heterogeneous nuclear ribonucleoprotein A3 OS=Homo sapiens OX=9606 GN=HNRNPA3 PE=1 SV=2 4.41 2817.1 - 1.13E+06 - - - 1.1127 - 3.209 0.588 - 573.2 1 2 1 0.0018 13 0 0 0 1.97E+07 1.12E+07 - - - 8.2564 0.9981 221125_WJC_METTL3_EV_vs_WT_F04.15798.15798.3 9.96E-06 14/44 R.LYFLQC[160.03]ETC[160.03]HSR.C sp|P20042|IF2B_HUMAN 1 1612.7126 0.63 49563 15798 3 1612.704351 538.5782 Eukaryotic translation initiation factor 2 subunit 2 OS=Homo sapiens OX=9606 GN=EIF2S2 PE=1 SV=2 6.73 2817.4 - 863309 - - - -5.1354 - 2.121 0.403 - 200 1 2 0 -0.0083 12 0 0 0 1.09E+07 1.71E+07 - - - 5.1149 1 221125_WJC_METTL3_EV_vs_WT_F04.15805.15805.3 5.86E-08 15/64 K.VLAVNQENEHLMEDYEK[136.11].L "sp|O43707|ACTN4_HUMAN,tr|F5GXS2|F5GXS2_HUMAN,tr|H7C144|H7C144_HUMAN" 3 2067.9663 0.69 49568 15805 3 2067.965419 690.3294 Alpha-actinin-4 OS=Homo sapiens OX=9606 GN=ACTN4 PE=1 SV=2 4.25 2818.3 - 854006 - - - -0.412 - 2.759 0.592 - 195.5 1 2 0 -0.0009 17 0 0 0 7.66E+06 1.11E+07 - - - 7.7038 0.996 221125_WJC_METTL3_EV_vs_WT_F04.15813.15813.3 0.0385 13/48 K.IQAQIDR[166.11]FPIGDR[166.11].E sp|Q96S59|RANB9_HUMAN 1 1547.8323 1.35 49576 15813 3 1547.830511 516.9514 Ran-binding protein 9 OS=Homo sapiens OX=9606 GN=RANBP9 PE=1 SV=1 5.96 2819.2 - 453652 - - - -1.1655 - 1.872 0.289 - 155.3 1 2 1 -0.0018 13 0 0 0 6.17E+06 4.57E+06 - - - 3.4616 0.9998 221125_WJC_METTL3_EV_vs_WT_F04.15814.15814.3 0.000956 Nov-48 K.VVVVVPNEEDWK[136.11]K[136.11].R "sp|Q1KMD3|HNRL2_HUMAN,tr|H3BQZ7|H3BQZ7_HUMAN" 2 1555.8581 1.71 49577 15814 3 1555.858017 519.6266 Heterogeneous nuclear ribonucleoprotein U-like protein 2 OS=Homo sapiens OX=9606 GN=HNRNPUL2 PE=1 SV=1 4.68 2819.3 - 426909 - - - -0.0495 - 1.92 0.396 - 149 1 2 0 -0.0001 13 0 0 0 7.60E+06 4.43E+06 - - - 4.7236 0.9979 221125_WJC_METTL3_EV_vs_WT_F04.15816.15816.2 1.38E-05 24-Dec K.SQFTITPGSEQIR[166.11].A "sp|Q99798|ACON_HUMAN,tr|A0A7I2V3F1|A0A7I2V3F1_HUMAN,tr|A0A7I2V5T4|A0A7I2V5T4_HUMAN,tr|A2A274|A2A274_HUMAN,tr|A0A7I2V586|A0A7I2V586_HUMAN,tr|A0A7I2V614|A0A7I2V614_HUMAN,tr|A0A7I2V5A1|A0A7I2V5A1_HUMAN,tr|A0A7I2V3U0|A0A7I2V3U0_HUMAN,tr|A0A7I2V538|A0A7I2V538_HUMAN" 9 1472.7499 0.69 49579 15816 2 1472.757227 737.3822 "Aconitate hydratase, mitochondrial OS=Homo sapiens OX=9606 GN=ACO2 PE=1 SV=2" 5.72 2819.6 - 299061 - - - 4.9907 - 2.383 0.512 - 516.9 1 2 0 0.0073 13 0 0 0 2.45E+06 3.55E+06 - - - 5.049 0.9993 221125_WJC_METTL3_EV_vs_WT_F04.15817.15817.3 0.00028 Nov-36 R.LQSGIC[160.03]HLFR[166.11].E "sp|P14868|SYDC_HUMAN,tr|C9J7S3|C9J7S3_HUMAN,tr|C9JLC1|C9JLC1_HUMAN" 3 1239.6422 1.11 49580 15817 3 1239.639876 414.2213 "Aspartate--tRNA ligase, cytoplasmic OS=Homo sapiens OX=9606 GN=DARS1 PE=1 SV=2" 8.26 2819.7 - 267115 - - - -1.8602 - 2.384 0.258 - 122.7 1 2 0 -0.0023 10 0 0 0 3.19E+06 2.88E+06 - - - 3.953 1 221125_WJC_METTL3_EV_vs_WT_F04.15820.15820.2 9.34E-11 17/26 K.AEAGAGSATEFQFR[166.11].G "sp|Q9NQ39|RS10L_HUMAN,sp|P46783|RS10_HUMAN" 2 1450.6716 1.32 49581 15820 2 1450.670584 726.3431 Putative 40S ribosomal protein S10-like OS=Homo sapiens OX=9606 GN=RPS10P5 PE=5 SV=1 4.53 2820.1 - 6.35E+06 - - - -0.719 - 3.601 0.591 - 1196.8 1 2 0 -0.001 14 0 0 0 8.63E+08 6.56E+08 - - - 6.6209 0.9999 221125_WJC_METTL3_EV_vs_WT_F04.15823.15823.2 4.11E-05 13/24 R.DTLVADNLDQATR.V "sp|Q9NTJ3|SMC4_HUMAN,tr|E9PD53|E9PD53_HUMAN" 2 1430.7001 2.88 49584 15823 2 1430.700201 716.3573 Structural maintenance of chromosomes protein 4 OS=Homo sapiens OX=9606 GN=SMC4 PE=1 SV=2 3.93 2820.4 - 1.08E+06 - - - 0.0447 - 2.572 0.523 - 556.5 1 2 0 0.0001 13 0 0 0 9.37E+06 3.25E+06 - - - 5.3284 0.9984 221125_WJC_METTL3_EV_vs_WT_F04.15827.15827.2 0.0229 24-Sep K.DAQPSFSAEDIAK[136.11].L "sp|P25205|MCM3_HUMAN,tr|J3KQ69|J3KQ69_HUMAN,tr|A0A499FHX9|A0A499FHX9_HUMAN" 3 1385.6554 0.41 49588 15827 2 1385.656512 693.835 DNA replication licensing factor MCM3 OS=Homo sapiens OX=9606 GN=MCM3 PE=1 SV=3 4.03 2820.9 - 387702 - - - 0.7845 - 1.526 0.27 - 58.4 1 2 0 0.0011 13 0 0 0 2.00E+06 4.90E+06 - - - 2.1196 0.9993 221125_WJC_METTL3_EV_vs_WT_F04.15829.15829.3 0.0053 Oct-40 K.AVLFC[160.03]LSEDKK.N "sp|P23528|COF1_HUMAN,tr|E9PP50|E9PP50_HUMAN,tr|G3V1A4|G3V1A4_HUMAN,tr|E9PQB7|E9PQB7_HUMAN,tr|E9PK25|E9PK25_HUMAN,tr|E9PLJ3|E9PLJ3_HUMAN,tr|E9PS23|E9PS23_HUMAN" 7 1308.6748 1.33 49590 15829 3 1308.671932 437.2322 Cofilin-1 OS=Homo sapiens OX=9606 GN=CFL1 PE=1 SV=3 6.1 2821.2 - 228478 - - - -2.1717 - 1.96 0.327 - 129.2 1 2 0 -0.0028 11 0 0 0 1.57E+08 1.18E+08 - - - 4.0967 0.9864 221125_WJC_METTL3_EV_vs_WT_F04.15830.15830.3 0.0179 Aug-36 K.AELAWLEHQK.K sp|Q5VT06|CE350_HUMAN 1 1223.6299 0.96 49591 15830 3 1223.627989 408.8839 Centrosome-associated protein 350 OS=Homo sapiens OX=9606 GN=CEP350 PE=1 SV=1 5.4 2821.3 - 186878 - - - -1.5389 - 1.627 0.164 - 66.4 1 2 0 -0.0019 10 0 0 0 1.82E+06 1.89E+06 - - - 1.7894 0.9999 221125_WJC_METTL3_EV_vs_WT_F04.15833.15833.3 0.0233 Nov-48 K.EMNPALGIDC[160.03]LHK.G "sp|P48643|TCPE_HUMAN,tr|E9PCA1|E9PCA1_HUMAN,tr|B7ZAR1|B7ZAR1_HUMAN,tr|E7ENZ3|E7ENZ3_HUMAN" 4 1496.7116 0.73 49592 15833 3 1496.710539 499.9111 T-complex protein 1 subunit epsilon OS=Homo sapiens OX=9606 GN=CCT5 PE=1 SV=1 5.32 2821.7 - 1.73E+06 - - - -0.6888 - 2.507 0.378 - 115.3 1 2 0 -0.001 13 0 0 0 1.13E+08 1.55E+08 - - - 5.246 0.9999 221125_WJC_METTL3_EV_vs_WT_F04.15835.15835.3 0.000436 Dec-52 K.AEAGAGSATEFQFR[166.11].G "sp|Q9NQ39|RS10L_HUMAN,sp|P46783|RS10_HUMAN" 2 1450.6716 1.24 49594 15835 3 1450.672027 484.5645 Putative 40S ribosomal protein S10-like OS=Homo sapiens OX=9606 GN=RPS10P5 PE=5 SV=1 4.53 2821.9 - 1.77E+06 - - - 0.2757 - 2.55 0.409 - 219.9 1 2 0 0.0004 14 0 0 0 7.47E+07 6.01E+07 - - - 5.5875 1 221125_WJC_METTL3_EV_vs_WT_F04.15838.15838.3 3.03E-07 15/56 K.ASEAGEVPFNHEILR[166.11].E "sp|Q7L5N1|CSN6_HUMAN,tr|E7EM64|E7EM64_HUMAN" 2 1677.835 1.7 49597 15838 3 1677.83602 560.2856 COP9 signalosome complex subunit 6 OS=Homo sapiens OX=9606 GN=COPS6 PE=1 SV=1 4.75 2822.2 - 832514 - - - 0.6055 - 2.797 0.525 - 297.8 1 2 0 0.001 15 0 0 0 7.39E+06 4.34E+06 - - - 7.0768 0.9999 221125_WJC_METTL3_EV_vs_WT_F04.15843.15843.3 4.54E-07 15/76 R.SAPAGASEPPPPGGVGLGIR[166.11].T "sp|Q8IWZ3|ANKH1_HUMAN,tr|E9PDP5|E9PDP5_HUMAN,tr|D6RHC4|D6RHC4_HUMAN" 3 1795.9456 2.28 49602 15843 3 1795.943583 599.6558 Ankyrin repeat and KH domain-containing protein 1 OS=Homo sapiens OX=9606 GN=ANKHD1 PE=1 SV=1 5.72 2822.9 - 460447 - - - -1.1326 - 2.558 0.446 - 218.9 1 2 0 -0.002 20 0 0 0 1.92E+07 8.44E+06 - - - 5.7905 0.9984 221125_WJC_METTL3_EV_vs_WT_F04.15849.15849.2 0.0382 20-Aug K.AVLFC[160.03]LSEDKK.N "sp|P23528|COF1_HUMAN,tr|E9PP50|E9PP50_HUMAN,tr|G3V1A4|G3V1A4_HUMAN,tr|E9PQB7|E9PQB7_HUMAN,tr|E9PK25|E9PK25_HUMAN,tr|E9PLJ3|E9PLJ3_HUMAN,tr|E9PS23|E9PS23_HUMAN" 7 1308.6748 1.73 49608 15849 2 1308.673961 655.3447 Cofilin-1 OS=Homo sapiens OX=9606 GN=CFL1 PE=1 SV=3 6.1 2823.7 - 215606 - - - -0.6212 - 1.547 0.246 - 185.7 1 2 0 -0.0008 11 0 0 0 2.40E+07 1.39E+07 - - - 2.038 1 221125_WJC_METTL3_EV_vs_WT_F04.15852.15852.2 4.92E-08 15/26 K.AEAGAGSATEFQFR.G "sp|Q9NQ39|RS10L_HUMAN,sp|P46783|RS10_HUMAN" 2 1440.6634 1.35 49610 15852 2 1440.662272 721.339 Putative 40S ribosomal protein S10-like OS=Homo sapiens OX=9606 GN=RPS10P5 PE=5 SV=1 4.53 2824 - 4.90E+07 - - - -0.7531 - 3.351 0.558 - 850 1 2 0 -0.0011 14 0 0 0 9.20E+08 6.80E+08 - - - 6.1966 0.9999 221125_WJC_METTL3_EV_vs_WT_F04.15854.15854.3 8.52E-07 Dec-52 K.AEAGAGSATEFQFR.G "sp|Q9NQ39|RS10L_HUMAN,sp|P46783|RS10_HUMAN" 2 1440.6634 1.24 49612 15854 3 1440.662732 481.2284 Putative 40S ribosomal protein S10-like OS=Homo sapiens OX=9606 GN=RPS10P5 PE=5 SV=1 4.53 2824.2 - 5.02E+06 - - - -0.4338 - 2.328 0.456 - 236.3 1 2 0 -0.0006 14 0 0 0 7.33E+07 5.93E+07 - - - 5.8694 1 221125_WJC_METTL3_EV_vs_WT_F04.15857.15857.3 2.51E-05 18/72 K.NLPPSGAVPVTGIPPHVVK[136.11].V "sp|Q13283|G3BP1_HUMAN,tr|A0A7I2V5M7|A0A7I2V5M7_HUMAN,tr|A0A7I2YQM1|A0A7I2YQM1_HUMAN,tr|A0A7P0P2U7|A0A7P0P2U7_HUMAN,tr|A0A7I2YQU8|A0A7I2YQU8_HUMAN,tr|A0A7I2V548|A0A7I2V548_HUMAN,tr|A0A7I2V651|A0A7I2V651_HUMAN,tr|A0A7I2V4D8|A0A7I2V4D8_HUMAN,tr|A0A7I2YQN9|A0A7I2YQN9_HUMAN" 9 1886.0869 1.27 49615 15857 3 1886.087717 629.7029 Ras GTPase-activating protein-binding protein 1 OS=Homo sapiens OX=9606 GN=G3BP1 PE=1 SV=1 8.76 2824.4 - 1.24E+06 - - - 0.4236 - 2.292 0.513 - 259.6 1 2 0 0.0008 19 0 0 0 1.38E+07 1.09E+07 - - - 6.297 0.9999 221125_WJC_METTL3_EV_vs_WT_F04.15859.15859.2 8.96E-08 13/24 K.ETIDAVPNAIPGR[166.11].T "sp|O43670|ZN207_HUMAN,tr|H0Y3M2|H0Y3M2_HUMAN,tr|J3QS27|J3QS27_HUMAN,tr|J3KTL1|J3KTL1_HUMAN,tr|J3QRS9|J3QRS9_HUMAN,tr|J3KRB6|J3KRB6_HUMAN,tr|X6R4W8|X6R4W8_HUMAN,tr|J3KRW6|J3KRW6_HUMAN" 8 1361.7178 0.63 49617 15859 2 1361.717822 681.8662 BUB3-interacting and GLEBS motif-containing protein ZNF207 OS=Homo sapiens OX=9606 GN=ZNF207 PE=1 SV=1 4.37 2824.7 - 725265 - - - -0.0198 - 2.507 0.557 - 390.1 1 2 0 0 13 0 0 0 2.68E+06 4.26E+06 - - - 5.5139 0.9977 221125_WJC_METTL3_EV_vs_WT_F04.15862.15862.3 0.000405 15/40 K.TR[166.11]DEYLSLVAR[166.11].L "sp|Q96RN5|MED15_HUMAN,tr|C9JM58|C9JM58_HUMAN,tr|G3V1P5|G3V1P5_HUMAN,tr|C9JGN2|C9JGN2_HUMAN,tr|C9J1I1|C9J1I1_HUMAN,tr|C9JZV5|C9JZV5_HUMAN,tr|C9JLN7|C9JLN7_HUMAN" 7 1341.7156 27.4 49620 15862 3 1341.719435 448.2458 Mediator of RNA polymerase II transcription subunit 15 OS=Homo sapiens OX=9606 GN=MED15 PE=1 SV=2 5.74 2825.1 - 510968 - - - 2.8926 - 2.454 0.341 - 398 1 2 1 0.0039 11 0 0 0 1.14E+08 4.16E+06 - - - 4.891 0.8626 221125_WJC_METTL3_EV_vs_WT_F04.15863.15863.3 0.0391 Jul-44 K.IKTEPLDFNDYK.V "sp|O60315|ZEB2_HUMAN,tr|U3KQ51|U3KQ51_HUMAN,tr|E7ESP8|E7ESP8_HUMAN,tr|E7EUW9|E7EUW9_HUMAN,tr|A0JP08|A0JP08_HUMAN,tr|A0A1B0GW50|A0A1B0GW50_HUMAN,tr|A0A1B0GV02|A0A1B0GV02_HUMAN,tr|A0A1X7SC99|A0A1X7SC99_HUMAN,tr|A0A1B0GVV8|A0A1B0GVV8_HUMAN" 9 1481.7402 0.59 49621 15863 3 1481.739311 494.9207 Zinc finger E-box-binding homeobox 2 OS=Homo sapiens OX=9606 GN=ZEB2 PE=1 SV=1 4.56 2825.2 - 451331 - - - -0.6067 - 1.632 0.107 - 48 1 2 1 -0.0009 12 0 0 0 2.47E+06 4.23E+06 - - - 1.0904 1 221125_WJC_METTL3_EV_vs_WT_F04.15865.15865.2 4.30E-07 24-Nov R.EVSFQSTGESEWK[136.11].D "sp|Q07021|C1QBP_HUMAN,tr|I3L3B0|I3L3B0_HUMAN,tr|I3L3Q7|I3L3Q7_HUMAN" 3 1520.6875 1.1 49623 15865 2 1520.691313 761.351 "Complement component 1 Q subcomponent-binding protein, mitochondrial OS=Homo sapiens OX=9606 GN=C1QBP PE=1 SV=1" 4.25 2825.5 - 394217 - - - 2.5383 - 2.304 0.617 - 351.8 1 2 0 0.0039 13 0 0 0 5.22E+07 4.73E+07 - - - 5.7391 0.9994 221125_WJC_METTL3_EV_vs_WT_F04.15866.15866.3 0.000237 Sep-64 R.TLVSAVPEESEMDPHVR.D "sp|Q96N67|DOCK7_HUMAN,tr|A0A1B0GVW2|A0A1B0GVW2_HUMAN,tr|A0A1B0GUE9|A0A1B0GUE9_HUMAN" 3 1894.9095 2.06 49624 15866 3 1894.910916 632.6438 Dedicator of cytokinesis protein 7 OS=Homo sapiens OX=9606 GN=DOCK7 PE=1 SV=4 4.4 2825.6 - 335973 - - - 0.7589 - 1.714 0.334 - 61.6 1 2 0 0.0014 17 0 0 0 6.24E+06 3.03E+06 - - - 3.6246 0.9979 221125_WJC_METTL3_EV_vs_WT_F04.15867.15867.3 0.0968 Jul-36 K.K[136.11]LGEWVGLC[160.03]K[136.11].L sp|P25398|RS12_HUMAN 1 1204.6609 1.68 49625 15867 3 1204.660056 402.5609 40S ribosomal protein S12 OS=Homo sapiens OX=9606 GN=RPS12 PE=1 SV=3 8.2 2825.7 - 281266 - - - -0.7131 - 1.248 0.325 - 71.6 1 2 0 -0.0009 10 0 0 0 4.46E+06 2.65E+06 - - - 2.8102 0.9987 221125_WJC_METTL3_EV_vs_WT_F04.15869.15869.2 0.00385 24-Sep K.ETIDAVPNAIPGR.T "sp|O43670|ZN207_HUMAN,tr|H0Y3M2|H0Y3M2_HUMAN,tr|J3QS27|J3QS27_HUMAN,tr|J3KTL1|J3KTL1_HUMAN,tr|J3QRS9|J3QRS9_HUMAN,tr|J3KRB6|J3KRB6_HUMAN,tr|X6R4W8|X6R4W8_HUMAN,tr|J3KRW6|J3KRW6_HUMAN" 8 1351.7096 -1 49627 15869 2 1351.711543 676.8621 BUB3-interacting and GLEBS motif-containing protein ZNF207 OS=Homo sapiens OX=9606 GN=ZNF207 PE=1 SV=1 4.37 2826 - 214628 - - - 1.453 - 1.65 0.31 - 172.2 1 2 0 0.002 13 0 0 0 0.00E+00 0.00E+00 - - - 2.6153 1 221125_WJC_METTL3_EV_vs_WT_F04.15874.15874.2 5.50E-10 30-Dec K.GNVGIGGSAVPPPPIK[136.11].H "sp|Q7Z739|YTHD3_HUMAN,tr|A0A087X0Q1|A0A087X0Q1_HUMAN,tr|A0A024R7W5|A0A024R7W5_HUMAN,tr|A0A087WY31|A0A087WY31_HUMAN" 4 1466.8337 1.56 49631 15874 2 1466.832807 734.4241 YTH domain-containing family protein 3 OS=Homo sapiens OX=9606 GN=YTHDF3 PE=1 SV=1 8.75 2826.6 - 344833 - - - -0.5843 - 2.494 0.603 - 295.4 1 2 0 -0.0009 16 0 0 0 3.73E+07 2.40E+07 - - - 5.7413 0.9998 221125_WJC_METTL3_EV_vs_WT_F04.15876.15876.2 0.00113 24-Oct K.EMNPALGIDC[160.03]LHK[136.11].G "sp|P48643|TCPE_HUMAN,tr|E9PCA1|E9PCA1_HUMAN,tr|B7ZAR1|B7ZAR1_HUMAN,tr|E7ENZ3|E7ENZ3_HUMAN" 4 1504.7258 1.07 49633 15876 2 1504.725513 753.3702 T-complex protein 1 subunit epsilon OS=Homo sapiens OX=9606 GN=CCT5 PE=1 SV=1 5.32 2826.7 - 1.85E+06 - - - -0.1708 - 2 0.438 - 362.5 1 2 0 -0.0003 13 0 0 0 1.29E+07 1.21E+07 - - - 4.055 0.9999 221125_WJC_METTL3_EV_vs_WT_F04.15877.15877.2 0.014 20-Dec R.TAAENEFVTLK.K "sp|P48668|K2C6C_HUMAN,sp|P12035|K2C3_HUMAN,sp|P04259|K2C6B_HUMAN,sp|P02538|K2C6A_HUMAN" 4 1221.6241 10.31 49634 15877 2 1221.624027 611.8193 "Keratin, type II cytoskeletal 6C OS=Homo sapiens OX=9606 GN=KRT6C PE=1 SV=3" 4.53 2826.8 - 1.85E+06 - - - -0.0745 - 2.42 0.44 - 510.3 1 2 0 -0.0001 11 0 0 0 4.88E+07 4.73E+06 - - - 4.6816 1 221125_WJC_METTL3_EV_vs_WT_F04.15878.15878.3 1.51E-05 17/72 K.VGDFVATDLDTGRPSTTVR.Y sp|Q02413|DSG1_HUMAN 1 2006.0069 999 49635 15878 3 2006.008109 669.6762 Desmoglein-1 OS=Homo sapiens OX=9606 GN=DSG1 PE=1 SV=2 4.43 2826.9 - 1.70E+06 - - - 0.6112 - 2.849 0.523 - 350 1 2 0 0.0012 19 0 0 0 1.24E+08 0.00E+00 - - - 6.9428 0.9999 221125_WJC_METTL3_EV_vs_WT_F04.15879.15879.3 2.20E-05 Aug-40 R.MDYVEINIDHK.F "sp|Q00341|VIGLN_HUMAN,tr|A0A024R4E5|A0A024R4E5_HUMAN,tr|H7C0A4|H7C0A4_HUMAN,tr|H0Y394|H0Y394_HUMAN" 4 1375.6442 1.17 49636 15879 3 1375.642001 459.5553 Vigilin OS=Homo sapiens OX=9606 GN=HDLBP PE=1 SV=2 4.54 2826.9 - 1.65E+06 - - - -1.6 - 1.722 0.47 - 100.6 1 2 0 -0.0022 11 0 0 0 8.36E+06 7.15E+06 - - - 5.3234 0.999 221125_WJC_METTL3_EV_vs_WT_F04.15880.15880.3 8.54E-05 Aug-40 R.MDYVEINIDHK[136.11].F "sp|Q00341|VIGLN_HUMAN,tr|A0A024R4E5|A0A024R4E5_HUMAN,tr|H7C0A4|H7C0A4_HUMAN,tr|H0Y394|H0Y394_HUMAN" 4 1383.6584 1.36 49637 15880 3 1383.656073 462.2267 Vigilin OS=Homo sapiens OX=9606 GN=HDLBP PE=1 SV=2 4.54 2827 - 1.54E+06 - - - -1.6832 - 1.749 0.31 - 105.1 1 2 0 -0.0023 11 0 0 0 1.00E+07 7.35E+06 - - - 3.5837 0.9999 221125_WJC_METTL3_EV_vs_WT_F04.15881.15881.2 0.000305 20-Dec K.AVLFC[160.03]LSEDK[136.11]K[136.11].N "sp|P23528|COF1_HUMAN,tr|E9PP50|E9PP50_HUMAN,tr|G3V1A4|G3V1A4_HUMAN,tr|E9PQB7|E9PQB7_HUMAN,tr|E9PK25|E9PK25_HUMAN,tr|E9PLJ3|E9PLJ3_HUMAN,tr|E9PS23|E9PS23_HUMAN" 7 1324.7032 1.72 49638 15881 2 1324.702768 663.3589 Cofilin-1 OS=Homo sapiens OX=9606 GN=CFL1 PE=1 SV=3 6.1 2827.1 - 1.44E+06 - - - -0.3065 - 2.481 0.532 - 624.2 1 2 0 -0.0004 11 0 0 0 2.33E+07 1.35E+07 - - - 5.4284 0.9999 221125_WJC_METTL3_EV_vs_WT_F04.15884.15884.3 7.59E-06 17/52 K.ISNYGWDQSDK[136.11]FVK[136.11].L sp|Q9HB71|CYBP_HUMAN 1 1701.8333 3.87 49641 15884 3 1701.832224 568.2851 Calcyclin-binding protein OS=Homo sapiens OX=9606 GN=CACYBP PE=1 SV=2 5.96 2827.4 - 950084 - - - -0.6534 - 2.964 0.463 - 353.2 1 2 1 -0.0011 14 0 0 0 2.59E+07 6.70E+06 - - - 6.5892 0.957 221125_WJC_METTL3_EV_vs_WT_F04.15885.15885.2 0.00231 16-Sep V.LFC[160.03]LSEDK[136.11]K[136.11].N "sp|P23528|COF1_HUMAN,tr|E9PP50|E9PP50_HUMAN,tr|G3V1A4|G3V1A4_HUMAN,tr|E9PQB7|E9PQB7_HUMAN,tr|E9PK25|E9PK25_HUMAN,tr|E9PLJ3|E9PLJ3_HUMAN,tr|E9PS23|E9PS23_HUMAN" 7 1154.5976 2.08 49642 15885 2 1154.593991 578.3061 Cofilin-1 OS=Homo sapiens OX=9606 GN=CFL1 PE=1 SV=3 6.06 2827.5 - 913540 - - - -3.1656 - 1.874 0.496 - 317 1 1 0 -0.0037 9 0 0 0 1.70E+07 8.18E+06 - - - 4.5204 1 221125_WJC_METTL3_EV_vs_WT_F04.15886.15886.3 1.75E-08 13/48 K.FSQC[160.03]GHVMFAEIK.M "sp|Q9P2K5|MYEF2_HUMAN,tr|A0A0A0MR39|A0A0A0MR39_HUMAN,tr|A0A0C4DGV1|A0A0C4DGV1_HUMAN,tr|A0A087WUT0|A0A087WUT0_HUMAN,tr|H0YKS1|H0YKS1_HUMAN,tr|A0A0A0MQW0|A0A0A0MQW0_HUMAN" 6 1552.7167 0.92 49643 15886 3 1552.713614 518.5795 Myelin expression factor 2 OS=Homo sapiens OX=9606 GN=MYEF2 PE=1 SV=3 6.74 2827.7 - 813421 - - - -1.9585 - 2.543 0.573 - 81.4 1 2 0 -0.003 13 0 0 0 9.51E+06 1.03E+07 - - - 7.4581 0.9998 221125_WJC_METTL3_EV_vs_WT_F04.15887.15887.2 0.000676 18-Dec R.ISGLIYEETR.G sp|P62805|H4_HUMAN 1 1179.6136 1.05 49644 15887 2 1179.613501 590.8141 Histone H4 OS=Homo sapiens OX=9606 GN=H4C1 PE=1 SV=2 4.53 2827.8 - 728708 - - - -0.0441 - 2.266 0.422 - 481.5 1 2 0 -0.0001 10 0 0 0 4.71E+06 4.48E+06 - - - 4.4412 0.9998 221125_WJC_METTL3_EV_vs_WT_F04.15888.15888.2 0.0109 20-Dec K.AQTEWNTGTWR[166.11].N sp|Q969E2|SCAM4_HUMAN 1 1358.6243 1.07 49645 15888 2 1358.62296 680.3194 Secretory carrier-associated membrane protein 4 OS=Homo sapiens OX=9606 GN=SCAMP4 PE=1 SV=1 6.05 2827.9 - 688667 - - - -0.9738 - 2.435 0.385 - 734.8 1 2 0 -0.0013 11 0 0 0 5.85E+06 5.48E+06 - - - 4.2917 1 221125_WJC_METTL3_EV_vs_WT_F04.15890.15890.3 1.46E-08 14/48 K.FSQC[160.03]GHVMFAEIK[136.11].M "sp|Q9P2K5|MYEF2_HUMAN,tr|A0A0A0MR39|A0A0A0MR39_HUMAN,tr|A0A0C4DGV1|A0A0C4DGV1_HUMAN,tr|A0A087WUT0|A0A087WUT0_HUMAN,tr|H0YKS1|H0YKS1_HUMAN,tr|A0A0A0MQW0|A0A0A0MQW0_HUMAN" 6 1560.7309 0.97 49647 15890 3 1560.730615 521.2509 Myelin expression factor 2 OS=Homo sapiens OX=9606 GN=MYEF2 PE=1 SV=3 6.74 2828.2 - 615508 - - - -0.1538 - 2.698 0.59 - 102.1 1 2 0 -0.0002 13 0 0 0 1.01E+07 1.04E+07 - - - 7.8088 1 221125_WJC_METTL3_EV_vs_WT_F04.15895.15895.2 2.35E-10 13/30 K.GNVGIGGSAVPPPPIK.H "sp|Q7Z739|YTHD3_HUMAN,tr|A0A087X0Q1|A0A087X0Q1_HUMAN,tr|A0A024R7W5|A0A024R7W5_HUMAN,tr|A0A087WY31|A0A087WY31_HUMAN" 4 1458.8195 1.56 49651 15895 2 1458.814707 730.417 YTH domain-containing family protein 3 OS=Homo sapiens OX=9606 GN=YTHDF3 PE=1 SV=1 8.75 2828.8 - 817975 - - - -3.2609 - 2.745 0.642 - 343.8 1 2 0 -0.0048 16 0 0 0 1.68E+07 1.08E+07 - - - 6.2639 0.9999 221125_WJC_METTL3_EV_vs_WT_F04.15896.15896.2 2.23E-06 14/28 K.NQLTSNPENTVFDAK[136.11].R "sp|P11021|BIP_HUMAN,tr|A0A7P0TB36|A0A7P0TB36_HUMAN,tr|A0A7P0TAI0|A0A7P0TAI0_HUMAN" 3 1684.8148 0.68 49652 15896 2 1684.813421 843.4147 Endoplasmic reticulum chaperone BiP OS=Homo sapiens OX=9606 GN=HSPA5 PE=1 SV=2 4.37 2828.9 - 2.55E+06 - - - -0.806 - 2.908 0.464 - 543.9 1 2 0 -0.0014 15 0 0 0 7.85E+07 1.15E+08 - - - 5.0921 1 221125_WJC_METTL3_EV_vs_WT_F04.15898.15898.2 0.0123 17/28 K.NQLTSNPENTVFDAK.R "sp|P11021|BIP_HUMAN,tr|A0A7P0TB36|A0A7P0TB36_HUMAN,tr|A0A7P0TAI0|A0A7P0TAI0_HUMAN" 3 1676.8006 0.68 49654 15898 2 1676.803224 839.4076 Endoplasmic reticulum chaperone BiP OS=Homo sapiens OX=9606 GN=HSPA5 PE=1 SV=2 4.37 2829.1 - 1.31E+06 - - - 1.5774 - 3.122 0.529 - 793.4 1 2 0 0.0026 15 0 0 0 7.85E+07 1.15E+08 - - - 5.7464 0.9998 221125_WJC_METTL3_EV_vs_WT_F04.15900.15900.3 6.50E-07 13/48 R.LYK[136.11]LELEQTYQAK[136.11].L sp|Q03252|LMNB2_HUMAN 1 1641.8949 1.06 49656 15900 3 1641.893763 548.3056 Lamin-B2 OS=Homo sapiens OX=9606 GN=LMNB2 PE=1 SV=4 6.14 2829.3 - 1.02E+06 - - - -0.6767 - 2.652 0.439 - 220 1 2 1 -0.0011 13 0 0 0 5.38E+06 5.05E+06 - - - 6.0785 0.9998 221125_WJC_METTL3_EV_vs_WT_F04.15901.15901.2 0.00178 20-Dec K.AQTEWNTGTWR.N sp|Q969E2|SCAM4_HUMAN 1 1348.616 0.92 49657 15901 2 1348.614144 675.3153 Secretory carrier-associated membrane protein 4 OS=Homo sapiens OX=9606 GN=SCAMP4 PE=1 SV=1 6.05 2829.4 - 950771 - - - -1.3859 - 2.519 0.48 - 750.9 1 2 0 -0.0019 11 0 0 0 5.85E+06 6.34E+06 - - - 5.085 1 221125_WJC_METTL3_EV_vs_WT_F04.15903.15903.3 1.51E-07 15/52 R.TFYEDEMASHLDSK.F "sp|Q9ULX6|AKP8L_HUMAN,tr|A0A7P0TAJ5|A0A7P0TAJ5_HUMAN,tr|A0A7P0TAE3|A0A7P0TAE3_HUMAN" 3 1671.7087 1.12 49659 15903 3 1671.709582 558.2435 A-kinase anchor protein 8-like OS=Homo sapiens OX=9606 GN=AKAP8L PE=1 SV=4 4.31 2829.6 - 838529 - - - 0.5563 - 2.352 0.613 - 196.4 1 2 0 0.0009 14 0 0 0 1.06E+07 9.46E+06 - - - 7.647 0.9998 221125_WJC_METTL3_EV_vs_WT_F04.15904.15904.3 0.00544 Oct-36 R.FKPEELVDYK.S "sp|O60361|NDK8_HUMAN,sp|P22392|NDKB_HUMAN,tr|Q32Q12|Q32Q12_HUMAN" 3 1266.6496 2.21 49660 15904 3 1266.647557 423.2238 Putative nucleoside diphosphate kinase OS=Homo sapiens OX=9606 GN=NME2P1 PE=5 SV=1 4.68 2829.7 - 738674 - - - -1.6161 - 1.895 0.399 - 140.3 1 2 0 -0.002 10 0 0 0 5.42E+06 2.45E+06 - - - 4.8547 0.9992 221125_WJC_METTL3_EV_vs_WT_F04.15905.15905.3 2.35E-05 Nov-40 K.ITLQDVVSHSK[136.11].K "sp|P46940|IQGA1_HUMAN,tr|H0YLE8|H0YLE8_HUMAN,tr|A0A0J9YXZ5|A0A0J9YXZ5_HUMAN" 3 1233.6809 0.94 49661 15905 3 1233.678199 412.2342 Ras GTPase-activating-like protein IQGAP1 OS=Homo sapiens OX=9606 GN=IQGAP1 PE=1 SV=1 6.74 2829.9 - 716583 - - - -2.1505 - 2.105 0.302 - 126.8 1 2 0 -0.0027 11 0 0 0 1.11E+07 1.18E+07 - - - 4.0207 1 221125_WJC_METTL3_EV_vs_WT_F04.15908.15908.2 3.53E-06 Dec-32 R.VLLQASQDENFGNTTPR.N "sp|P57740|NU107_HUMAN,tr|G3V1T4|G3V1T4_HUMAN" 2 1888.9279 2.25 49664 15908 2 1888.930773 945.4712 Nuclear pore complex protein Nup107 OS=Homo sapiens OX=9606 GN=NUP107 PE=1 SV=1 4.37 2830.2 - 602210 - - - 1.5183 - 2.942 0.623 - 343.7 1 2 0 0.0029 17 0 0 0 7.39E+06 3.28E+06 - - - 6.2946 1 221125_WJC_METTL3_EV_vs_WT_F04.15909.15909.3 4.86E-05 13/40 K.ITLQDVVSHSK.K "sp|P46940|IQGA1_HUMAN,tr|H0YLE8|H0YLE8_HUMAN,tr|A0A0J9YXZ5|A0A0J9YXZ5_HUMAN" 3 1225.6667 0.94 49665 15909 3 1225.66661 409.5628 Ras GTPase-activating-like protein IQGAP1 OS=Homo sapiens OX=9606 GN=IQGAP1 PE=1 SV=1 6.74 2830.4 - 489124 - - - -0.0343 - 2.431 0.472 - 171.2 1 2 0 0 11 0 0 0 1.11E+07 1.18E+07 - - - 6.3258 0.9998 221125_WJC_METTL3_EV_vs_WT_F04.15913.15913.3 1.52E-05 13/44 R.TVITEEFKVPDK.M sp|Q96I24|FUBP3_HUMAN 1 1404.75 1.84 49667 15913 3 1404.749919 469.2573 Far upstream element-binding protein 3 OS=Homo sapiens OX=9606 GN=FUBP3 PE=1 SV=2 4.68 2830.8 - 3.62E+06 - - - -0.0911 - 2.46 0.477 - 172.9 1 2 1 -0.0001 12 0 0 0 1.57E+09 8.56E+08 - - - 6.3532 0.999 221125_WJC_METTL3_EV_vs_WT_F04.15914.15914.3 0.00217 16/44 R.TVITEEFK[136.11]VPDK[136.11].M sp|Q96I24|FUBP3_HUMAN 1 1420.7784 1.84 49668 15914 3 1420.782728 474.6001 Far upstream element-binding protein 3 OS=Homo sapiens OX=9606 GN=FUBP3 PE=1 SV=2 4.68 2830.9 - 3.06E+06 - - - 3.0131 - 2.852 0.386 - 261.1 1 2 1 0.0043 12 0 0 0 1.57E+09 8.56E+08 - - - 5.7473 0.9999 221125_WJC_METTL3_EV_vs_WT_F04.15915.15915.3 0.00652 Dec-52 K.QPAEHLQLLEEAAK[136.11].E "sp|P33992|MCM5_HUMAN,tr|B1AHA9|B1AHA9_HUMAN" 2 1583.8399 0.42 49669 15915 3 1583.838851 528.9539 DNA replication licensing factor MCM5 OS=Homo sapiens OX=9606 GN=MCM5 PE=1 SV=5 4.75 2830.9 - 1.74E+06 - - - -0.644 - 2.364 0.363 - 232.2 1 2 0 -0.001 14 0 0 0 7.40E+06 1.75E+07 - - - 4.8732 0.9998 221125_WJC_METTL3_EV_vs_WT_F04.15916.15916.3 1.49E-05 Oct-44 K.IADDK[136.11]YNDTFWK[136.11].E "sp|P14625|ENPL_HUMAN,tr|A0A7P0T917|A0A7P0T917_HUMAN,tr|A0A7P0T823|A0A7P0T823_HUMAN,tr|A0A7P0TAE1|A0A7P0TAE1_HUMAN,tr|H0YIV0|H0YIV0_HUMAN,tr|A0A7P0TAY2|A0A7P0TAY2_HUMAN,tr|A0A087WT78|A0A087WT78_HUMAN,tr|A0A7P0TAT8|A0A7P0TAT8_HUMAN" 8 1530.7326 1.03 49670 15916 3 1530.730288 511.2515 Endoplasmin OS=Homo sapiens OX=9606 GN=HSP90B1 PE=1 SV=1 4.43 2831 - 1.23E+06 - - - -1.4836 - 2.277 0.504 - 117.2 1 2 1 -0.0023 12 0 0 0 1.53E+07 1.49E+07 - - - 6.4393 0.9997 221125_WJC_METTL3_EV_vs_WT_F04.15917.15917.3 0.00103 Oct-44 K.IADDKYNDTFWK.E "sp|P14625|ENPL_HUMAN,tr|A0A7P0T917|A0A7P0T917_HUMAN,tr|A0A7P0T823|A0A7P0T823_HUMAN,tr|A0A7P0TAE1|A0A7P0TAE1_HUMAN,tr|H0YIV0|H0YIV0_HUMAN,tr|A0A7P0TAY2|A0A7P0TAY2_HUMAN,tr|A0A087WT78|A0A087WT78_HUMAN,tr|A0A7P0TAT8|A0A7P0TAT8_HUMAN" 8 1514.7042 0.76 49671 15917 3 1514.701358 505.9087 Endoplasmin OS=Homo sapiens OX=9606 GN=HSP90B1 PE=1 SV=1 4.43 2831 - 1.19E+06 - - - -1.8492 - 2.102 0.491 - 122.6 1 2 1 -0.0028 12 0 0 0 1.55E+07 2.03E+07 - - - 6.0726 0.9898 221125_WJC_METTL3_EV_vs_WT_F04.15918.15918.2 0.000282 18-Aug R.MDSFDEDLAR.P "sp|Q9Y2W1|TR150_HUMAN,tr|A0A3B3ITZ9|A0A3B3ITZ9_HUMAN" 2 1197.4972 6.74 49672 15918 2 1197.495275 599.7559 Thyroid hormone receptor-associated protein 3 OS=Homo sapiens OX=9606 GN=THRAP3 PE=1 SV=2 3.84 2831.2 - 1.15E+06 - - - -1.61 - 2.068 0.554 - 271.6 1 1 0 -0.0019 10 0 0 0 5.91E+06 8.77E+05 - - - 5.1603 0.9998 221125_WJC_METTL3_EV_vs_WT_F04.15919.15919.2 0.00021 13/24 K.SLQFDVAGTSSER.S sp|Q5VT06|CE350_HUMAN 1 1395.663 1.89 49673 15919 2 1395.661246 698.8388 Centrosome-associated protein 350 OS=Homo sapiens OX=9606 GN=CEP350 PE=1 SV=1 4.37 2831.3 - 1.03E+06 - - - -1.2732 - 2.604 0.477 - 611.2 1 2 0 -0.0018 13 0 0 0 1.06E+07 5.61E+06 - - - 5.0199 1 221125_WJC_METTL3_EV_vs_WT_F04.15920.15920.3 1.92E-11 20/60 K.QFSSADEAALK[136.11]EPIIK[136.11].K "sp|Q9HCC0|MCCB_HUMAN,tr|A0A804HJC1|A0A804HJC1_HUMAN,tr|A0A804HK37|A0A804HK37_HUMAN,tr|A0A804HJ24|A0A804HJ24_HUMAN,tr|A0A804HL02|A0A804HL02_HUMAN,tr|A0A804HKE8|A0A804HKE8_HUMAN,tr|A0A804HJ84|A0A804HJ84_HUMAN,tr|A0A804HLJ9|A0A804HLJ9_HUMAN,tr|A0A804HJL2|A0A804HJL2_HUMAN,tr|A0A804HJ31|A0A804HJ31_HUMAN" 10 1761.9484 1.43 49674 15920 3 1761.949348 588.3234 "Methylcrotonoyl-CoA carboxylase beta chain, mitochondrial OS=Homo sapiens OX=9606 GN=MCCC2 PE=1 SV=1" 4.68 2831.4 - 1.02E+06 - - - 0.5573 - 3.569 0.678 - 561.5 1 2 1 0.001 16 0 0 0 1.63E+07 1.14E+07 - - - 9.3633 1 221125_WJC_METTL3_EV_vs_WT_F04.15921.15921.3 0.000123 20/56 K.LEDLPAEQWNHATVR.N "sp|Q9UPW6|SATB2_HUMAN,tr|C9JR56|C9JR56_HUMAN" 2 1777.8747 6.97 49675 15921 3 1777.874711 593.6322 DNA-binding protein SATB2 OS=Homo sapiens OX=9606 GN=SATB2 PE=1 SV=2 4.65 2831.6 - 1.01E+06 - - - -0.0202 - 3.431 0.528 - 714.6 1 2 0 0 15 0 0 0 1.20E+07 1.73E+06 - - - 7.6436 0.9469 221125_WJC_METTL3_EV_vs_WT_F04.15922.15922.2 0.000258 20-Aug K.NFGQELAQVQH.S "sp|Q15643|TRIPB_HUMAN,tr|H0YJ97|H0YJ97_HUMAN" 2 1269.6102 - 49676 15922 2 1269.606666 635.8124 Thyroid receptor-interacting protein 11 OS=Homo sapiens OX=9606 GN=TRIP11 PE=1 SV=3 5.24 2831.7 - 937143 - - - -2.7827 - 1.606 0.474 - 133.3 1 1 0 -0.0035 11 0 0 0 - - - - - 3.8225 0.9999 221125_WJC_METTL3_EV_vs_WT_F04.15923.15923.3 8.21E-10 18/60 K.QFSSADEAALKEPIIK.K "sp|Q9HCC0|MCCB_HUMAN,tr|A0A804HJC1|A0A804HJC1_HUMAN,tr|A0A804HK37|A0A804HK37_HUMAN,tr|A0A804HJ24|A0A804HJ24_HUMAN,tr|A0A804HL02|A0A804HL02_HUMAN,tr|A0A804HKE8|A0A804HKE8_HUMAN,tr|A0A804HJ84|A0A804HJ84_HUMAN,tr|A0A804HLJ9|A0A804HLJ9_HUMAN,tr|A0A804HJL2|A0A804HJL2_HUMAN,tr|A0A804HJ31|A0A804HJ31_HUMAN" 10 1745.92 1.45 49677 15923 3 1745.922187 582.9806 "Methylcrotonoyl-CoA carboxylase beta chain, mitochondrial OS=Homo sapiens OX=9606 GN=MCCC2 PE=1 SV=1" 4.68 2831.8 - 761042 - - - 1.2721 - 3.27 0.616 - 443 1 2 1 0.0022 16 0 0 0 1.67E+07 1.15E+07 - - - 8.4472 0.9901 221125_WJC_METTL3_EV_vs_WT_F04.15924.15924.3 0.000943 17/76 R.SAPAGASEPPPPGGVGLGIR.T "sp|Q8IWZ3|ANKH1_HUMAN,tr|E9PDP5|E9PDP5_HUMAN,tr|D6RHC4|D6RHC4_HUMAN" 3 1785.9373 2.06 49678 15924 3 1786.941733 596.3197 Ankyrin repeat and KH domain-containing protein 1 OS=Homo sapiens OX=9606 GN=ANKHD1 PE=1 SV=1 5.72 2832 - 747698 - - - 562.3859 - 2.627 0.31 - 149.4 1 2 0 1.0044 20 0 0 0 9.97E+06 4.84E+06 - - - 4.0611 0.9999 221125_WJC_METTL3_EV_vs_WT_F04.15925.15925.2 3.49E-06 13/24 K.SLQFDVAGTSSER[166.11].S sp|Q5VT06|CE350_HUMAN 1 1405.6713 1.89 49679 15925 2 1405.670628 703.8429 Centrosome-associated protein 350 OS=Homo sapiens OX=9606 GN=CEP350 PE=1 SV=1 4.37 2832.1 - 623226 - - - -0.4731 - 2.289 0.517 - 389 1 2 0 -0.0007 13 0 0 0 1.06E+07 5.61E+06 - - - 4.9847 0.9999 221125_WJC_METTL3_EV_vs_WT_F04.15926.15926.2 6.74E-09 26-Nov K.NPDEVSYAGDNFVR.Y sp|O95391|SLU7_HUMAN 1 1581.706 0.83 49680 15926 2 1581.706593 791.8603 Pre-mRNA-splicing factor SLU7 OS=Homo sapiens OX=9606 GN=SLU7 PE=1 SV=2 4.03 2832.2 - 602509 - - - 0.4065 - 2.667 0.562 - 430.4 1 2 0 0.0006 14 0 0 0 5.63E+06 6.80E+06 - - - 5.6534 0.9661 221125_WJC_METTL3_EV_vs_WT_F04.15930.15930.2 0.000681 Aug-34 R.LLEGEDAHLSSSQFSSGS.Q sp|P02533|K1C14_HUMAN 1 1849.833 - 49684 15930 2 1849.835726 925.9238 "Keratin, type I cytoskeletal 14 OS=Homo sapiens OX=9606 GN=KRT14 PE=1 SV=4" 4.13 2832.7 - 431661 - - - 1.4731 - 1.739 0.408 - 107.8 1 1 0 0.0027 18 0 0 0 - - - - - 3.414 1 221125_WJC_METTL3_EV_vs_WT_F04.15934.15934.2 7.65E-05 24-Dec R.FSGSGSGTDFTLK.L "sp|A2NJV5|KV229_HUMAN,sp|A0A087WW87|KV240_HUMAN,sp|P06310|KV230_HUMAN,sp|A0A075B6S2|KVD29_HUMAN,sp|P01614|KVD40_HUMAN,sp|P01615|KVD28_HUMAN,sp|A0A075B6S6|KVD30_HUMAN,sp|A0A075B6P5|KV228_HUMAN,sp|A0A0A0MRZ7|KVD26_HUMAN" 9 1302.6092 21.13 49687 15934 2 1302.60846 652.3119 Immunoglobulin kappa variable 2-29 OS=Homo sapiens OX=9606 GN=IGKV2-29 PE=3 SV=2 5.84 2833.2 - 5.32E+06 - - - -0.565 - 2.597 0.609 - 272.1 1 2 0 -0.0007 13 0 0 0 8.91E+07 4.22E+06 - - - 5.9882 1 221125_WJC_METTL3_EV_vs_WT_F04.15935.15935.3 5.28E-05 15/72 K.NLPPSGAVPVTGIPPHVVK.V "sp|Q13283|G3BP1_HUMAN,tr|A0A7I2V5M7|A0A7I2V5M7_HUMAN,tr|A0A7I2YQM1|A0A7I2YQM1_HUMAN,tr|A0A7P0P2U7|A0A7P0P2U7_HUMAN,tr|A0A7I2YQU8|A0A7I2YQU8_HUMAN,tr|A0A7I2V548|A0A7I2V548_HUMAN,tr|A0A7I2V651|A0A7I2V651_HUMAN,tr|A0A7I2V4D8|A0A7I2V4D8_HUMAN,tr|A0A7I2YQN9|A0A7I2YQN9_HUMAN" 9 1878.0727 1.47 49688 15935 3 1878.072429 627.0315 Ras GTPase-activating protein-binding protein 1 OS=Homo sapiens OX=9606 GN=G3BP1 PE=1 SV=1 8.76 2833.2 - 2.71E+06 - - - -0.1539 - 2.433 0.538 - 173.6 1 2 0 -0.0003 19 0 0 0 4.09E+07 2.79E+07 - - - 6.7225 0.9987 221125_WJC_METTL3_EV_vs_WT_F04.15936.15936.2 7.61E-06 13/22 R.TVITEEFKVPDK.M sp|Q96I24|FUBP3_HUMAN 1 1404.75 1.83 49689 15936 2 1404.749032 703.3823 Far upstream element-binding protein 3 OS=Homo sapiens OX=9606 GN=FUBP3 PE=1 SV=2 4.68 2833.3 - 1.85E+06 - - - -0.7225 - 2.367 0.509 - 449.9 1 2 1 -0.001 12 0 0 0 1.27E+08 6.95E+07 - - - 5.0672 1 221125_WJC_METTL3_EV_vs_WT_F04.15938.15938.3 2.45E-06 Oct-52 R.FAIGSQVSEHSIIK[136.11].D "sp|P33992|MCM5_HUMAN,tr|B1AHB1|B1AHB1_HUMAN" 2 1522.8235 0.48 49691 15938 3 1522.822283 508.6151 DNA replication licensing factor MCM5 OS=Homo sapiens OX=9606 GN=MCM5 PE=1 SV=5 6.75 2833.5 - 1.55E+06 - - - -0.7946 - 2.154 0.488 - 60.2 1 2 0 -0.0012 14 0 0 0 1.71E+07 3.56E+07 - - - 6.0196 0.835 221125_WJC_METTL3_EV_vs_WT_F04.15939.15939.2 0.221 18-Dec V.ITEEFK[136.11]VPDK[136.11].M sp|Q96I24|FUBP3_HUMAN 1 1220.6624 1.97 49692 15939 2 1220.661171 611.3385 Far upstream element-binding protein 3 OS=Homo sapiens OX=9606 GN=FUBP3 PE=1 SV=2 4.68 2833.6 - 1.07E+06 - - - -0.9691 - 2.319 0.327 - 472.1 1 1 1 -0.0012 10 0 0 0 7.94E+07 4.03E+07 - - - 3.8037 0.9858 221125_WJC_METTL3_EV_vs_WT_F04.15940.15940.2 3.43E-05 24-Nov L.SSTPVSPIELDAK[136.11].K sp|Q9H7S9|ZN703_HUMAN 1 1350.7122 1.57 49693 15940 2 1350.714167 676.3634 Zinc finger protein 703 OS=Homo sapiens OX=9606 GN=ZNF703 PE=1 SV=1 4.37 2833.7 - 880911 - - - 1.4481 - 2.07 0.495 - 388.4 1 1 0 0.002 13 0 0 0 1.86E+07 1.19E+07 - - - 4.5637 0.9999 221125_WJC_METTL3_EV_vs_WT_F04.15941.15941.3 8.79E-08 15/44 K.LK[136.11]DVLLQVDDER[166.11].R sp|P35579|MYH9_HUMAN 1 1459.8001 1.05 49694 15941 3 1459.802497 487.6073 Myosin-9 OS=Homo sapiens OX=9606 GN=MYH9 PE=1 SV=4 4.23 2833.8 - 861194 - - - 1.6221 - 2.624 0.551 - 376.4 1 2 1 0.0024 12 0 0 0 8.63E+06 8.22E+06 - - - 7.3565 0.9999 221125_WJC_METTL3_EV_vs_WT_F04.15943.15943.3 0.000319 13/36 R.SLHDAIMIVR[166.11].R sp|Q99832|TCPH_HUMAN 1 1163.636 0.21 49696 15943 3 1163.634597 388.886 T-complex protein 1 subunit eta OS=Homo sapiens OX=9606 GN=CCT7 PE=1 SV=2 6.46 2834.1 - 595266 - - - -1.2349 - 1.926 0.448 - 270.2 1 2 0 -0.0014 10 0 0 0 1.53E+06 7.33E+06 - - - 5.4485 1 221125_WJC_METTL3_EV_vs_WT_F04.15944.15944.2 2.94E-13 17/32 R.VLLQASQDENFGNTTPR[166.11].N "sp|P57740|NU107_HUMAN,tr|G3V1T4|G3V1T4_HUMAN" 2 1898.9362 2.22 49697 15944 2 1898.932587 950.4754 Nuclear pore complex protein Nup107 OS=Homo sapiens OX=9606 GN=NUP107 PE=1 SV=1 4.37 2834.2 - 588180 - - - -1.8895 - 3.417 0.603 - 928.2 1 2 0 -0.0036 17 0 0 0 7.28E+06 3.28E+06 - - - 6.5146 0.9746 221125_WJC_METTL3_EV_vs_WT_F04.15947.15947.2 1.05 Jul-36 K.VGDFVATDLDTGRPSTTVR.Y sp|Q02413|DSG1_HUMAN 1 2006.0069 999 49700 15947 2 2006.007669 1004.0107 Desmoglein-1 OS=Homo sapiens OX=9606 GN=DSG1 PE=1 SV=2 4.43 2834.6 - 307255 - - - 0.3918 - 0.989 0.139 - 32.3 1 2 0 0.0008 19 0 0 0 1.49E+06 0.00E+00 - - - 0.0402 1 221125_WJC_METTL3_EV_vs_WT_F04.15948.15948.2 6.57E-09 15/40 K.AVGTPGGGGGGAVPGISAMSR.G sp|P48634|PRC2A_HUMAN 1 1754.8734 1.17 49701 15948 2 1754.868877 878.444 Protein PRRC2A OS=Homo sapiens OX=9606 GN=PRRC2A PE=1 SV=3 9.79 2834.8 - 306774 - - - -2.5586 - 2.914 0.574 - 331.6 1 2 0 -0.0045 21 0 0 0 2.40E+07 2.04E+07 - - - 5.9086 0.9173 221125_WJC_METTL3_EV_vs_WT_F04.15949.15949.2 1.19 30-May R.QAQSPAGVSSEVEVLK[136.11].A "sp|Q13136|LIPA1_HUMAN,tr|E9PJZ7|E9PJZ7_HUMAN,tr|A0A2R8Y7R9|A0A2R8Y7R9_HUMAN" 3 1635.8559 0.4 49702 15949 2 1635.857685 818.9352 Liprin-alpha-1 OS=Homo sapiens OX=9606 GN=PPFIA1 PE=1 SV=1 4.53 2834.9 - 257670 - - - 1.082 - 0.918 0.081 - 36.1 1 2 0 0.0018 16 0 0 0 5.64E+05 1.40E+06 - - - -0.5716 0.8538 221125_WJC_METTL3_EV_vs_WT_F04.15952.15952.2 0.211 18-Dec V.ITEEFKVPDK.M sp|Q96I24|FUBP3_HUMAN 1 1204.634 1.97 49703 15952 2 1204.633797 603.3243 Far upstream element-binding protein 3 OS=Homo sapiens OX=9606 GN=FUBP3 PE=1 SV=2 4.68 2835.3 - 4.28E+06 - - - -0.1303 - 2.36 0.315 - 456.5 1 1 1 -0.0002 10 0 0 0 7.94E+07 4.03E+07 - - - 3.7643 0.9993 221125_WJC_METTL3_EV_vs_WT_F04.15954.15954.3 0.000897 Dec-56 R.ILNEMRDQYEQMAEK.N "sp|P08779|K1C16_HUMAN,tr|K7ENW6|K7ENW6_HUMAN" 2 1896.871 157.94 49705 15954 3 1896.868456 633.2976 "Keratin, type I cytoskeletal 16 OS=Homo sapiens OX=9606 GN=KRT16 PE=1 SV=4" 4.41 2835.4 - 2.07E+06 - - - -1.3327 - 1.988 0.418 - 183.8 1 2 1 -0.0025 15 0 0 0 7.35E+07 4.65E+05 - - - 4.9926 0.9996 221125_WJC_METTL3_EV_vs_WT_F04.15956.15956.3 0.000148 Nov-40 K.AADR[166.11]LEQELLR[166.11].D "sp|Q6PK04|CC137_HUMAN,tr|I3L0U5|I3L0U5_HUMAN" 2 1332.7265 2.91 49707 15956 3 1332.724084 445.2494 Coiled-coil domain-containing protein 137 OS=Homo sapiens OX=9606 GN=CCDC137 PE=1 SV=1 4.68 2835.6 - 605604 - - - -1.7776 - 2.382 0.431 - 129 1 2 1 -0.0024 11 0 0 0 1.68E+07 5.76E+06 - - - 5.8102 1 221125_WJC_METTL3_EV_vs_WT_F04.15957.15957.2 2.13E-08 16/40 K.AVGTPGGGGGGAVPGISAMSR[166.11].G sp|P48634|PRC2A_HUMAN 1 1764.8816 1.17 49708 15957 2 1764.882479 883.4481 Protein PRRC2A OS=Homo sapiens OX=9606 GN=PRRC2A PE=1 SV=3 9.79 2835.7 - 584628 - - - 0.4771 - 3.153 0.54 - 376 1 2 0 0.0008 21 0 0 0 2.40E+07 2.04E+07 - - - 5.8525 1 221125_WJC_METTL3_EV_vs_WT_F04.15959.15959.2 8.45E-06 22-Oct K.EIDDEANSYFQR.L "sp|A5YKK6|CNOT1_HUMAN,tr|H3BR89|H3BR89_HUMAN,tr|H3BMH0|H3BMH0_HUMAN" 3 1485.6372 1.46 49710 15959 2 1485.631195 743.8259 CCR4-NOT transcription complex subunit 1 OS=Homo sapiens OX=9606 GN=CNOT1 PE=1 SV=2 3.92 2836 - 274725 - - - -4.0434 - 2.086 0.661 - 341 1 2 0 -0.006 12 0 0 0 3.54E+06 2.43E+06 - - - 5.8558 0.986 221125_WJC_METTL3_EV_vs_WT_F04.15961.15961.2 8.39E-06 28-Oct K.SGVENEDQQEVILVR[166.11].T "sp|Q2TBE0|C19L2_HUMAN,tr|H0YE03|H0YE03_HUMAN,tr|H7C3G7|H7C3G7_HUMAN" 3 1723.8616 -1 49712 15961 2 1723.849608 862.9381 CWF19-like protein 2 OS=Homo sapiens OX=9606 GN=CWF19L2 PE=1 SV=4 4 2836.3 - 202784 - - - -6.964 - 1.971 0.465 - 149.1 1 2 0 -0.012 15 0 0 0 0.00E+00 0.00E+00 - - - 4.1399 0.9999 221125_WJC_METTL3_EV_vs_WT_F04.15963.15963.2 2.55E-06 15/38 R.SAPAGASEPPPPGGVGLGIR.T "sp|Q8IWZ3|ANKH1_HUMAN,tr|E9PDP5|E9PDP5_HUMAN,tr|D6RHC4|D6RHC4_HUMAN" 3 1785.9373 2.11 49713 15963 2 1785.937617 893.9759 Ankyrin repeat and KH domain-containing protein 1 OS=Homo sapiens OX=9606 GN=ANKHD1 PE=1 SV=1 5.72 2836.5 - 669171 - - - 0.1512 - 2.617 0.57 - 277.5 1 2 0 0.0003 20 0 0 0 1.48E+07 6.98E+06 - - - 5.6161 0.9998 221125_WJC_METTL3_EV_vs_WT_F04.15965.15965.3 1.86E-05 Dec-44 K.YYVTIIDAPGHR[166.11].D "sp|P68104|EF1A1_HUMAN,sp|Q5VTE0|EF1A3_HUMAN,tr|A0A7I2V659|A0A7I2V659_HUMAN,tr|A0A7I2V3H3|A0A7I2V3H3_HUMAN,tr|Q5JR01|Q5JR01_HUMAN,tr|A0A7I2V5N4|A0A7I2V5N4_HUMAN,tr|A0A087WVQ9|A0A087WVQ9_HUMAN,tr|A6PW80|A6PW80_HUMAN,tr|A0A087WV01|A0A087WV01_HUMAN" 9 1413.728 0.38 49714 15965 3 1413.723713 472.2499 Elongation factor 1-alpha 1 OS=Homo sapiens OX=9606 GN=EEF1A1 PE=1 SV=1 6.74 2836.7 - 1.25E+07 - - - -3.0466 - 2.122 0.469 - 163.6 1 2 0 -0.0043 12 0 0 0 9.13E+07 2.39E+08 - - - 5.8531 1 221125_WJC_METTL3_EV_vs_WT_F04.15966.15966.3 0.000388 13/56 R.EELGFRPEYSASQLK.G "sp|P09874|PARP1_HUMAN,tr|A0A7I2V5E9|A0A7I2V5E9_HUMAN,tr|A0A7I2V625|A0A7I2V625_HUMAN,tr|A0A7I2V3E1|A0A7I2V3E1_HUMAN" 4 1752.8683 1.35 49715 15966 3 1752.867251 585.2967 Poly [ADP-ribose] polymerase 1 OS=Homo sapiens OX=9606 GN=PARP1 PE=1 SV=4 4.79 2836.8 - 2.40E+06 - - - -0.5785 - 2.371 0.476 - 243.4 1 2 0 -0.001 15 0 0 0 3.43E+07 2.55E+07 - - - 6.0993 0.9997 221125_WJC_METTL3_EV_vs_WT_F04.15967.15967.3 0.00238 14/56 R.EELGFR[166.11]PEYSASQLK[136.11].G "sp|P09874|PARP1_HUMAN,tr|A0A7I2V5E9|A0A7I2V5E9_HUMAN,tr|A0A7I2V625|A0A7I2V625_HUMAN,tr|A0A7I2V3E1|A0A7I2V3E1_HUMAN" 4 1770.8907 1.33 49716 15967 3 1770.895286 591.3042 Poly [ADP-ribose] polymerase 1 OS=Homo sapiens OX=9606 GN=PARP1 PE=1 SV=4 4.79 2836.8 - 2.50E+06 - - - 2.5699 - 2.575 0.361 - 261.9 1 2 0 0.0046 15 0 0 0 3.21E+07 2.42E+07 - - - 5.0316 1 221125_WJC_METTL3_EV_vs_WT_F04.15968.15968.3 2.00E-05 Dec-52 R.FAIGSQVSEHSIIK.D "sp|P33992|MCM5_HUMAN,tr|B1AHB1|B1AHB1_HUMAN" 2 1514.8093 0.47 49717 15968 3 1514.808592 505.9437 DNA replication licensing factor MCM5 OS=Homo sapiens OX=9606 GN=MCM5 PE=1 SV=5 6.75 2836.9 - 2.44E+06 - - - -0.4628 - 2.312 0.48 - 101.5 1 2 0 -0.0007 14 0 0 0 1.67E+07 3.52E+07 - - - 6.1186 0.9888 221125_WJC_METTL3_EV_vs_WT_F04.15969.15969.2 3.38E-05 24-Oct L.SSTPVSPIELDAK.K sp|Q9H7S9|ZN703_HUMAN 1 1342.698 1.57 49718 15969 2 1342.698273 672.3563 Zinc finger protein 703 OS=Homo sapiens OX=9606 GN=ZNF703 PE=1 SV=1 4.37 2836.9 - 1.73E+06 - - - 0.1951 - 2.078 0.442 - 257.4 1 1 0 0.0003 13 0 0 0 1.86E+07 1.19E+07 - - - 4.1827 1 221125_WJC_METTL3_EV_vs_WT_F04.15970.15970.3 1.33E-09 13/56 K.GFVEPDHYVVVGAQR.D "sp|P02786|TFR1_HUMAN,tr|G3V0E5|G3V0E5_HUMAN" 2 1671.8369 1.72 49719 15970 3 1671.836328 558.2862 Transferrin receptor protein 1 OS=Homo sapiens OX=9606 GN=TFRC PE=1 SV=2 5.32 2837 - 1.69E+06 - - - -0.3451 - 2.729 0.631 - 203.1 1 2 0 -0.0006 15 0 0 0 1.84E+07 1.07E+07 - - - 8.1945 0.9991 221125_WJC_METTL3_EV_vs_WT_F04.15972.15972.2 1.34E-06 22-Oct K.YYVTIIDAPGHR[166.11].D "sp|P68104|EF1A1_HUMAN,sp|Q5VTE0|EF1A3_HUMAN,tr|A0A7I2V659|A0A7I2V659_HUMAN,tr|A0A7I2V3H3|A0A7I2V3H3_HUMAN,tr|Q5JR01|Q5JR01_HUMAN,tr|A0A7I2V5N4|A0A7I2V5N4_HUMAN,tr|A0A087WVQ9|A0A087WVQ9_HUMAN,tr|A6PW80|A6PW80_HUMAN,tr|A0A087WV01|A0A087WV01_HUMAN" 9 1413.728 0.3 49721 15972 2 1413.723016 707.8713 Elongation factor 1-alpha 1 OS=Homo sapiens OX=9606 GN=EEF1A1 PE=1 SV=1 6.74 2837.2 - 1.08E+06 - - - -3.5396 - 2.062 0.493 - 377 1 2 0 -0.005 12 0 0 0 5.95E+06 2.01E+07 - - - 4.5848 0.9979 221125_WJC_METTL3_EV_vs_WT_F04.15974.15974.3 0.00335 Dec-56 K.ILQAFPDMHNSNISK.L "sp|P35712|SOX6_HUMAN,sp|P35711|SOX5_HUMAN,tr|F5H0I3|F5H0I3_HUMAN" 3 1713.8508 6.08 49723 15974 3 1713.85646 572.2909 Transcription factor SOX-6 OS=Homo sapiens OX=9606 GN=SOX6 PE=1 SV=3 6.74 2837.5 - 623224 - - - 3.2792 - 2.205 0.296 - 132.5 1 2 0 0.0056 15 0 0 0 5.79E+06 9.52E+05 - - - 3.9018 0.9998 221125_WJC_METTL3_EV_vs_WT_F04.15975.15975.3 0.0155 14/40 R.QAEVLAEFERR.K sp|O43172|PRP4_HUMAN 1 1346.6943 2.64 49724 15975 3 1346.692927 449.9054 U4\U6 small nuclear ribonucleoprotein Prp4 OS=Homo sapiens OX=9606 GN=PRPF4 PE=1 SV=2 4.79 2837.6 - 567194 - - - -0.9921 - 2.404 0.328 - 339.9 1 2 0 -0.0013 11 0 0 0 7.29E+06 2.76E+06 - - - 4.6883 0.9995 221125_WJC_METTL3_EV_vs_WT_F04.15978.15978.2 0.00518 Jul-38 R.SAPAGASEPPPPGGVGLGIR[166.11].T "sp|Q8IWZ3|ANKH1_HUMAN,tr|E9PDP5|E9PDP5_HUMAN,tr|D6RHC4|D6RHC4_HUMAN" 3 1795.9456 2.23 49727 15978 2 1795.942977 898.9801 Ankyrin repeat and KH domain-containing protein 1 OS=Homo sapiens OX=9606 GN=ANKHD1 PE=1 SV=1 5.72 2838 - 328594 - - - -1.47 - 1.632 0.449 - 36.2 1 2 0 -0.0026 20 0 0 0 1.06E+07 4.78E+06 - - - 3.5607 0.9984 221125_WJC_METTL3_EV_vs_WT_F04.15980.15980.3 0.0111 14/52 K.AQIHDLVLVGGSTR[166.11].L "sp|P0DMV8|HS71A_HUMAN,sp|P0DMV9|HS71B_HUMAN,tr|V9GZ37|V9GZ37_HUMAN,tr|A0A0G2JIW1|A0A0G2JIW1_HUMAN" 4 1474.8131 0.23 49728 15980 3 1474.809469 492.6117 Heat shock 70 kDa protein 1A OS=Homo sapiens OX=9606 GN=HSPA1A PE=1 SV=1 6.79 2838.2 - 834346 - - - -2.4932 - 2.344 0.254 - 227.7 1 2 0 -0.0037 14 0 0 0 3.63E+06 1.55E+07 - - - 3.6347 0.9999 221125_WJC_METTL3_EV_vs_WT_F04.15982.15982.2 3.53E-07 20-Oct R.C[160.03]TPSVISFGSK[136.11].N "sp|Q92598|HS105_HUMAN,tr|R4GN69|R4GN69_HUMAN" 2 1189.5893 0.16 49729 15982 2 1189.588512 595.8019 Heat shock protein 105 kDa OS=Homo sapiens OX=9606 GN=HSPH1 PE=1 SV=1 8.22 2838.4 - 3.35E+06 - - - -0.6288 - 1.951 0.527 - 374.9 1 2 0 -0.0007 11 0 0 0 1.33E+07 8.24E+07 - - - 4.7412 1 221125_WJC_METTL3_EV_vs_WT_F04.15983.15983.2 1.26E-11 18/26 R.VVNQYQELVQNEAK.C "sp|Q8NEM7|SP20H_HUMAN,tr|B4E2D5|B4E2D5_HUMAN,tr|R4GND2|R4GND2_HUMAN,tr|H7C5F9|H7C5F9_HUMAN,tr|F6S7C4|F6S7C4_HUMAN" 5 1660.842 1.21 49730 15983 2 1660.842379 831.4283 Transcription factor SPT20 homolog OS=Homo sapiens OX=9606 GN=SUPT20H PE=1 SV=2 4.53 2838.5 - 1.71E+06 - - - 0.1981 - 3.298 0.678 - 1352.2 1 2 0 0.0003 14 0 0 0 2.62E+07 2.17E+07 - - - 7.0432 1 221125_WJC_METTL3_EV_vs_WT_F04.15984.15984.2 8.31E-07 16/26 R.VVNQYQELVQNEAK[136.11].C "sp|Q8NEM7|SP20H_HUMAN,tr|B4E2D5|B4E2D5_HUMAN,tr|R4GND2|R4GND2_HUMAN,tr|H7C5F9|H7C5F9_HUMAN,tr|F6S7C4|F6S7C4_HUMAN" 5 1668.8563 1.21 49731 15984 2 1668.854087 835.4354 Transcription factor SPT20 homolog OS=Homo sapiens OX=9606 GN=SUPT20H PE=1 SV=2 4.53 2838.7 - 1.61E+06 - - - -1.2961 - 3.091 0.572 - 942.8 1 2 0 -0.0022 14 0 0 0 2.62E+07 2.17E+07 - - - 6.097 0.9999 221125_WJC_METTL3_EV_vs_WT_F04.15986.15986.2 5.59E-07 14/28 R.ASYVAPLTAQPATYR.A sp|Q96PK6|RBM14_HUMAN 1 1607.8308 1.89 49733 15986 2 1607.830985 804.9227 RNA-binding protein 14 OS=Homo sapiens OX=9606 GN=RBM14 PE=1 SV=2 8.63 2838.9 - 1.34E+06 - - - 0.1418 - 2.57 0.538 - 370.4 1 2 0 0.0002 15 0 0 0 5.75E+07 3.05E+07 - - - 5.3352 1 221125_WJC_METTL3_EV_vs_WT_F04.15987.15987.2 2.25E-09 16/26 H.VSDTSVVLSMDNNR.N "sp|P19013|K2C4_HUMAN,sp|P13647|K2C5_HUMAN,tr|H0YI76|H0YI76_HUMAN,tr|H0YIN9|H0YIN9_HUMAN" 4 1535.725 999 49734 15987 2 1535.723625 768.8698 "Keratin, type II cytoskeletal 4 OS=Homo sapiens OX=9606 GN=KRT4 PE=1 SV=5" 4.21 2839 - 939345 - - - -0.8765 - 3.638 0.709 - 934.3 1 1 0 -0.0013 14 0 0 0 1.76E+07 0.00E+00 - - - 7.518 0.9981 221125_WJC_METTL3_EV_vs_WT_F04.15989.15989.3 0.153 Oct-36 K.VALEIFQHSK.Y "sp|Q9NYK5|RM39_HUMAN,tr|C9JG87|C9JG87_HUMAN" 2 1170.6397 1.02 49736 15989 3 1170.638054 391.2205 "39S ribosomal protein L39, mitochondrial OS=Homo sapiens OX=9606 GN=MRPL39 PE=1 SV=3" 6.72 2839.2 - 863877 - - - -1.4129 - 1.798 0.248 - 106.3 1 2 0 -0.0017 10 0 0 0 8.10E+06 7.96E+06 - - - 3.0178 0.9873 221125_WJC_METTL3_EV_vs_WT_F04.15990.15990.3 0.0021 Oct-56 R.ASYVAPLTAQPATYR.A sp|Q96PK6|RBM14_HUMAN 1 1607.8308 1.94 49737 15990 3 1607.821099 536.9509 RNA-binding protein 14 OS=Homo sapiens OX=9606 GN=RBM14 PE=1 SV=2 8.63 2839.2 - 802560 - - - -6.0069 - 1.734 0.362 - 64.6 1 2 0 -0.0097 15 0 0 0 2.10E+07 1.08E+07 - - - 4.0095 1 221125_WJC_METTL3_EV_vs_WT_F04.15996.15996.2 1.66E-09 15/34 R.GATGEPEVMEPALEGTGK.E "sp|Q9H6R4|NOL6_HUMAN,tr|A0A0A0MRW6|A0A0A0MRW6_HUMAN" 2 1771.8298 1.1 49743 15996 2 1771.821549 886.9222 Nucleolar protein 6 OS=Homo sapiens OX=9606 GN=NOL6 PE=1 SV=2 4.09 2840 - 331591 - - - -4.6737 - 2.872 0.66 - 573.8 1 2 0 -0.0083 18 0 0 0 7.14E+06 6.51E+06 - - - 6.5069 0.9997 221125_WJC_METTL3_EV_vs_WT_F04.16001.16001.3 0.000328 Dec-48 K.QSLEASLAETEGR.Y "sp|P13645|K1C10_HUMAN,tr|A0A1B0GVI3|A0A1B0GVI3_HUMAN" 2 1389.6736 205.53 49746 16001 3 1389.676211 464.2318 "Keratin, type I cytoskeletal 10 OS=Homo sapiens OX=9606 GN=KRT10 PE=1 SV=6" 4.25 2840.6 - 8.20E+06 - - - 1.8882 - 1.915 0.398 - 218.1 1 2 0 0.0026 13 0 0 0 1.55E+08 7.54E+05 - - - 4.7382 1 221125_WJC_METTL3_EV_vs_WT_F04.16002.16002.2 3.75E-08 22-Nov R.AEEENEFQIPGR[166.11].T sp|Q8N0X7|SPART_HUMAN 1 1427.6556 1.28 49747 16002 2 1427.659299 714.8351 Spartin OS=Homo sapiens OX=9606 GN=SPART PE=1 SV=1 4.09 2840.6 - 1.89E+06 - - - 2.5608 - 2.485 0.612 - 391 1 2 0 0.0037 12 0 0 0 5.22E+07 4.07E+07 - - - 5.9552 0.9999 221125_WJC_METTL3_EV_vs_WT_F04.16004.16004.3 0.000105 15/52 R.VVNQYQELVQNEAK.C "sp|Q8NEM7|SP20H_HUMAN,tr|B4E2D5|B4E2D5_HUMAN,tr|R4GND2|R4GND2_HUMAN,tr|H7C5F9|H7C5F9_HUMAN,tr|F6S7C4|F6S7C4_HUMAN" 5 1660.842 1.52 49749 16004 3 1660.843019 554.6213 Transcription factor SPT20 homolog OS=Homo sapiens OX=9606 GN=SUPT20H PE=1 SV=2 4.53 2840.8 - 1.49E+06 - - - 0.5834 - 2.004 0.41 - 285.8 1 2 0 0.001 14 0 0 0 1.12E+07 7.34E+06 - - - 4.9582 0.9997 221125_WJC_METTL3_EV_vs_WT_F04.16008.16008.3 0.00162 Dec-52 K.SLTTSQYLMHEVAK[136.11].Q "sp|Q9NZB2|F120A_HUMAN,tr|A0A0C4DH52|A0A0C4DH52_HUMAN" 2 1614.8167 0.62 49753 16008 3 1614.813784 539.2795 Constitutive coactivator of PPAR-gamma-like protein 1 OS=Homo sapiens OX=9606 GN=FAM120A PE=1 SV=2 6.47 2841.1 - 1.38E+06 - - - -1.8014 - 1.976 0.39 - 94.6 1 2 0 -0.0029 14 0 0 0 1.25E+07 2.01E+07 - - - 4.6973 1 221125_WJC_METTL3_EV_vs_WT_F04.16009.16009.3 6.38E-07 Nov-44 R.AHLVAVFNEYQR[166.11].M "sp|P50995|ANX11_HUMAN,tr|H0Y6E1|H0Y6E1_HUMAN" 2 1455.7498 2.02 49754 16009 3 1455.747003 486.2572 Annexin A11 OS=Homo sapiens OX=9606 GN=ANXA11 PE=1 SV=1 6.79 2841.2 - 1.10E+06 - - - -1.9337 - 2.544 0.536 - 146.1 1 2 0 -0.0028 12 0 0 0 1.17E+07 5.79E+06 - - - 7.1033 0.9991 221125_WJC_METTL3_EV_vs_WT_F04.16010.16010.2 1.91E-08 17/28 R.ILNEMRDQYEQMAEK.N "sp|P08779|K1C16_HUMAN,tr|K7ENW6|K7ENW6_HUMAN" 2 1896.871 999 49755 16010 2 1896.870796 949.4428 "Keratin, type I cytoskeletal 16 OS=Homo sapiens OX=9606 GN=KRT16 PE=1 SV=4" 4.41 2841.4 - 595862 - - - -0.0991 - 3.006 0.527 - 637 1 2 1 -0.0002 15 0 0 0 5.14E+06 0.00E+00 - - - 5.6393 0.9913 221125_WJC_METTL3_EV_vs_WT_F04.16011.16011.3 0.00628 16/52 K.GQVFVLSTHPYGC[160.03]R[166.11].V "sp|Q8TB72|PUM2_HUMAN,tr|A0A0C4DG68|A0A0C4DG68_HUMAN" 2 1629.7961 0.66 49756 16011 3 1629.790865 544.2726 Pumilio homolog 2 OS=Homo sapiens OX=9606 GN=PUM2 PE=1 SV=2 8.23 2841.5 - 583207 - - - -3.2219 - 1.865 0.237 - 218.9 1 2 0 -0.0053 14 0 0 0 2.92E+07 4.45E+07 - - - 2.8372 0.997 221125_WJC_METTL3_EV_vs_WT_F04.16012.16012.3 0.53 Sep-44 R.LIDLHSPSEIVK[136.11].Q "sp|P60866|RS20_HUMAN,tr|A0A7P0S5H5|A0A7P0S5H5_HUMAN,tr|G3XAN0|G3XAN0_HUMAN" 3 1357.7697 1.25 49757 16012 3 1357.769254 453.5972 40S ribosomal protein S20 OS=Homo sapiens OX=9606 GN=RPS20 PE=1 SV=1 5.32 2841.6 - 490516 - - - -0.3042 - 1.889 0.203 - 107 1 2 0 -0.0004 12 0 0 0 6.30E+07 5.05E+07 - - - 2.5662 0.9849 221125_WJC_METTL3_EV_vs_WT_F04.16014.16014.3 0.000465 Nov-52 K.SGKWEGLVYAPPGK.E "sp|Q9Y2W1|TR150_HUMAN,tr|A0A3B3ITZ9|A0A3B3ITZ9_HUMAN" 2 1487.7773 9.97 49759 16014 3 1487.785207 496.933 Thyroid hormone receptor-associated protein 3 OS=Homo sapiens OX=9606 GN=THRAP3 PE=1 SV=2 8.22 2841.8 - 423778 - - - 5.3382 - 2.402 0.35 - 148.2 1 2 1 0.0079 14 0 0 0 6.78E+06 6.80E+05 - - - 4.7688 0.9995 221125_WJC_METTL3_EV_vs_WT_F04.16016.16016.2 1.03E-05 13/34 R.GATGEPEVMEPALEGTGK[136.11].E "sp|Q9H6R4|NOL6_HUMAN,tr|A0A0A0MRW6|A0A0A0MRW6_HUMAN" 2 1779.844 1.1 49761 16016 2 1779.838486 890.9293 Nucleolar protein 6 OS=Homo sapiens OX=9606 GN=NOL6 PE=1 SV=2 4.09 2842.1 - 360522 - - - -3.1149 - 2.694 0.477 - 347.5 1 2 0 -0.0055 18 0 0 0 7.14E+06 6.51E+06 - - - 4.9989 1 221125_WJC_METTL3_EV_vs_WT_F04.16022.16022.2 1.07E-07 14/22 R.AEEENEFQIPGR.T sp|Q8N0X7|SPART_HUMAN 1 1417.6474 1.28 49765 16022 2 1417.647453 709.831 Spartin OS=Homo sapiens OX=9606 GN=SPART PE=1 SV=1 4.09 2842.8 - 3.94E+06 - - - 0.0564 - 2.787 0.638 - 609.8 1 2 0 0.0001 12 0 0 0 5.22E+07 4.07E+07 - - - 6.4501 0.9998 221125_WJC_METTL3_EV_vs_WT_F04.16025.16025.2 7.07E-05 18-Oct R.DDSNLYINVK.L "sp|P11586|C1TC_HUMAN,tr|F5H2F4|F5H2F4_HUMAN,tr|V9GYY3|V9GYY3_HUMAN" 3 1179.5772 0.35 49768 16025 2 1179.577912 590.7959 "C-1-tetrahydrofolate synthase, cytoplasmic OS=Homo sapiens OX=9606 GN=MTHFD1 PE=1 SV=4" 4.21 2843 - 2.16E+06 - - - 0.6307 - 1.878 0.476 - 262.1 1 2 0 0.0007 10 0 0 0 2.65E+07 7.48E+07 - - - 4.3156 0.99 221125_WJC_METTL3_EV_vs_WT_F04.16027.16027.3 0.000337 14/36 R.K[136.11]QVEEIFNLK[136.11].F "sp|P78347|GTF2I_HUMAN,tr|A0A494C0Q7|A0A494C0Q7_HUMAN,tr|A0A494C1K3|A0A494C1K3_HUMAN" 3 1262.7205 1.55 49770 16027 3 1262.719785 421.9141 General transcription factor II-I OS=Homo sapiens OX=9606 GN=GTF2I PE=1 SV=2 6.14 2843.2 - 1.32E+06 - - - -0.5963 - 2.46 0.057 - 406.5 1 2 0 -0.0008 10 0 0 0 3.33E+07 2.15E+07 - - - 1.8042 0.9975 221125_WJC_METTL3_EV_vs_WT_F04.16028.16028.3 5.96E-06 14/36 R.KQVEEIFNLK.F "sp|P78347|GTF2I_HUMAN,tr|A0A494C0Q7|A0A494C0Q7_HUMAN,tr|A0A494C1K3|A0A494C1K3_HUMAN" 3 1246.6921 1.55 49771 16028 3 1246.691973 416.5713 General transcription factor II-I OS=Homo sapiens OX=9606 GN=GTF2I PE=1 SV=2 6.14 2843.3 - 1.14E+06 - - - -0.1324 - 2.523 0.128 - 444.3 1 2 0 -0.0002 10 0 0 0 3.33E+07 2.15E+07 - - - 2.6697 0.9997 221125_WJC_METTL3_EV_vs_WT_F04.16030.16030.3 4.73E-05 Sep-48 K.ITESSLVEITEHK[136.11].D "sp|Q99590|SCAFB_HUMAN,tr|F8VXG7|F8VXG7_HUMAN,tr|A0A0A0MTP7|A0A0A0MTP7_HUMAN" 3 1492.7864 1.45 49773 16030 3 1492.783731 498.6028 Protein SCAF11 OS=Homo sapiens OX=9606 GN=SCAF11 PE=1 SV=2 4.75 2843.5 - 707707 - - - -1.8141 - 2.174 0.369 - 115.2 1 2 0 -0.0027 13 0 0 0 8.71E+06 6.01E+06 - - - 4.7587 0.9978 221125_WJC_METTL3_EV_vs_WT_F04.16032.16032.3 0.000185 15/48 K.HWELTAEGEEIAR[166.11].E "sp|Q9Y285|SYFA_HUMAN,tr|K7ER16|K7ER16_HUMAN,tr|K7ER00|K7ER00_HUMAN,tr|K7EK06|K7EK06_HUMAN" 4 1549.74 2.34 49775 16032 3 1550.744978 517.5873 Phenylalanine--tRNA ligase alpha subunit OS=Homo sapiens OX=9606 GN=FARSA PE=1 SV=3 4.48 2843.8 - 559315 - - - 648.4552 - 2.715 0.415 - 377.8 1 2 0 1.0049 13 0 0 0 3.09E+07 1.32E+07 - - - 5.5965 0.9583 221125_WJC_METTL3_EV_vs_WT_F04.16036.16036.2 8.83E-07 28-Dec G.GGFGGDGGLLSGNEK.V "sp|P13645|K1C10_HUMAN,tr|A0A1B0GVI3|A0A1B0GVI3_HUMAN" 2 1363.6368 1.31 49779 16036 2 1363.642094 682.8257 "Keratin, type I cytoskeletal 10 OS=Homo sapiens OX=9606 GN=KRT10 PE=1 SV=6" 4.37 2844.3 - 220522 - - - 3.8764 - 2.666 0.59 - 234.7 2 1 0 0.0053 15 0 0 0 2.15E+06 1.64E+06 - - - 5.6734 0.9999 221125_WJC_METTL3_EV_vs_WT_F04.16038.16038.2 1.36E-08 28-Nov R.ASYVAPLTAQPATYR[166.11].A sp|Q96PK6|RBM14_HUMAN 1 1617.839 1.89 49780 16038 2 1617.84009 809.9268 RNA-binding protein 14 OS=Homo sapiens OX=9606 GN=RBM14 PE=1 SV=2 8.63 2844.5 - 2.51E+06 - - - 0.657 - 2.241 0.56 - 260.7 1 2 0 0.0011 15 0 0 0 5.75E+07 3.05E+07 - - - 5.1607 1 221125_WJC_METTL3_EV_vs_WT_F04.16040.16040.3 7.45E-06 15/48 K.AALLNQHYQVNFK[136.11].G "sp|P07814|SYEP_HUMAN,tr|V9GYZ6|V9GYZ6_HUMAN" 2 1552.8242 0.94 49781 16040 3 1552.824289 518.6153 Bifunctional glutamate\proline--tRNA ligase OS=Homo sapiens OX=9606 GN=EPRS1 PE=1 SV=5 8.64 2844.7 - 2.41E+06 - - - 0.0818 - 3.251 0.511 - 347.8 1 2 0 0.0001 13 0 0 0 4.93E+07 5.23E+07 - - - 7.4336 1 221125_WJC_METTL3_EV_vs_WT_F04.16042.16042.3 1.04E-09 21/52 R.YLQLTQSELSSYHR.K "sp|Q8N5M4|TTC9C_HUMAN,tr|H0YDR3|H0YDR3_HUMAN" 2 1723.8529 1.43 49783 16042 3 1723.851856 575.6249 Tetratricopeptide repeat protein 9C OS=Homo sapiens OX=9606 GN=TTC9C PE=1 SV=1 6.75 2844.9 - 1.56E+06 - - - -0.634 - 3.369 0.665 - 478.3 1 2 0 -0.0011 14 0 0 0 1.94E+07 1.36E+07 - - - 9.1817 0.9999 221125_WJC_METTL3_EV_vs_WT_F04.16044.16044.2 2.20E-05 15/26 K.NGIAGSSLPPPPIK.H sp|Q9Y5A9|YTHD2_HUMAN 1 1346.7558 1.52 49785 16044 2 1346.753979 674.3852 YTH domain-containing family protein 2 OS=Homo sapiens OX=9606 GN=YTHDF2 PE=1 SV=2 8.75 2845.1 - 1.49E+06 - - - -1.3529 - 2.616 0.544 - 722.9 1 2 0 -0.0018 14 0 0 0 3.27E+07 2.16E+07 - - - 5.4716 0.9995 221125_WJC_METTL3_EV_vs_WT_F04.16053.16053.3 0.012 Dec-40 R.LAGIINFQR[166.11]PK[136.11].D sp|O00232|PSD12_HUMAN 1 1273.7626 0.79 49794 16053 3 1273.760449 425.5948 26S proteasome non-ATPase regulatory subunit 12 OS=Homo sapiens OX=9606 GN=PSMD12 PE=1 SV=3 11 2846.2 - 327097 - - - -1.6581 - 2.564 0.26 - 241 1 2 0 -0.0021 11 0 0 0 2.10E+06 2.65E+06 - - - 4.113 0.9998 221125_WJC_METTL3_EV_vs_WT_F04.16054.16054.2 0.00294 20-Oct K.SLESQVENLQK.T sp|P12270|TPR_HUMAN 1 1273.6514 1.7 49795 16054 2 1273.651129 637.833 Nucleoprotein TPR OS=Homo sapiens OX=9606 GN=TPR PE=1 SV=3 4.53 2846.3 - 272047 - - - -0.2088 - 2.322 0.426 - 242 1 2 0 -0.0003 11 0 0 0 2.19E+07 1.29E+07 - - - 4.4663 0.9996 221125_WJC_METTL3_EV_vs_WT_F04.16057.16057.2 1.97E-05 15/18 R.KQVEEIFNLK.F "sp|P78347|GTF2I_HUMAN,tr|A0A494C0Q7|A0A494C0Q7_HUMAN,tr|A0A494C1K3|A0A494C1K3_HUMAN" 3 1246.6921 1.35 49796 16057 2 1246.690332 624.3533 General transcription factor II-I OS=Homo sapiens OX=9606 GN=GTF2I PE=1 SV=2 6.14 2846.7 - 3.16E+06 - - - -1.4486 - 3.156 0.186 - 849.8 1 2 0 -0.0018 10 0 0 0 1.71E+07 1.27E+07 - - - 3.6223 1 221125_WJC_METTL3_EV_vs_WT_F04.16058.16058.3 0.000211 13/52 R.YLQLTQSELSSYHR[166.11].K "sp|Q8N5M4|TTC9C_HUMAN,tr|H0YDR3|H0YDR3_HUMAN" 2 1733.8612 1.43 49797 16058 3 1733.861184 578.961 Tetratricopeptide repeat protein 9C OS=Homo sapiens OX=9606 GN=TTC9C PE=1 SV=1 6.75 2846.8 - 2.40E+06 - - - -0.0202 - 2.865 0.514 - 156.3 1 2 0 0 14 0 0 0 1.94E+07 1.36E+07 - - - 7.0678 0.9999 221125_WJC_METTL3_EV_vs_WT_F04.16059.16059.2 1.80E-06 20-Dec R.SDSYVELSQYR[166.11].D "sp|P52298|NCBP2_HUMAN,tr|F8WE41|F8WE41_HUMAN" 2 1355.6233 1.15 49798 16059 2 1355.622865 678.8189 Nuclear cap-binding protein subunit 2 OS=Homo sapiens OX=9606 GN=NCBP2 PE=1 SV=1 4.37 2846.9 - 2.07E+06 - - - -0.3061 - 2.003 0.589 - 594.6 1 2 0 -0.0004 11 0 0 0 1.51E+07 1.32E+07 - - - 5.2704 0.9999 221125_WJC_METTL3_EV_vs_WT_F04.16060.16060.2 6.54E-05 24-Dec R.STNLNC[160.03]SVIADVR[166.11].H sp|Q96EL3|RM53_HUMAN 1 1457.7172 1.29 49799 16060 2 1457.716119 729.8659 "39S ribosomal protein L53, mitochondrial OS=Homo sapiens OX=9606 GN=MRPL53 PE=1 SV=1" 5.55 2846.9 - 1.71E+06 - - - -0.7395 - 2.801 0.53 - 460.3 1 2 0 -0.0011 13 0 0 0 3.83E+07 2.97E+07 - - - 5.5987 1 221125_WJC_METTL3_EV_vs_WT_F04.16061.16061.3 3.48E-06 17/52 K.DPEGFVGHPVNAFK[136.11].L sp|P13674|P4HA1_HUMAN 1 1520.7503 1.73 49800 16061 3 1520.747598 507.9241 Prolyl 4-hydroxylase subunit alpha-1 OS=Homo sapiens OX=9606 GN=P4HA1 PE=1 SV=2 5.32 2847 - 1.45E+06 - - - -1.7952 - 3.037 0.565 - 359.6 1 2 0 -0.0027 14 0 0 0 9.16E+07 5.31E+07 - - - 7.7906 0.9998 221125_WJC_METTL3_EV_vs_WT_F04.16063.16063.3 7.08E-05 17/64 K.AASDIAMTELPPTHPIR.L "sp|P62258|1433E_HUMAN,tr|K7EM20|K7EM20_HUMAN" 2 1818.9298 0.19 49802 16063 3 1818.924573 607.3172 14-3-3 protein epsilon OS=Homo sapiens OX=9606 GN=YWHAE PE=1 SV=1 5.32 2847.2 - 1.25E+06 - - - -2.8841 - 2.367 0.444 - 246.1 1 2 0 -0.0052 17 0 0 0 1.94E+07 1.02E+08 - - - 5.6654 0.9991 221125_WJC_METTL3_EV_vs_WT_F04.16065.16065.3 0.000924 Dec-52 K.QAETDHLILQASLK.G "sp|Q8IWJ2|GCC2_HUMAN,tr|H7BYJ9|H7BYJ9_HUMAN" 2 1565.8413 1.84 49804 16065 3 1565.836327 522.9544 GRIP and coiled-coil domain-containing protein 2 OS=Homo sapiens OX=9606 GN=GCC2 PE=1 SV=4 5.32 2847.5 - 957647 - - - -3.19 - 2.135 0.357 - 194.4 1 2 0 -0.005 14 0 0 0 6.90E+06 3.75E+06 - - - 4.5345 0.9898 221125_WJC_METTL3_EV_vs_WT_F04.16066.16066.2 0.262 20-Sep K.SLESQVENLQK[136.11].T sp|P12270|TPR_HUMAN 1 1281.6656 1.67 49805 16066 2 1281.669857 641.8401 Nucleoprotein TPR OS=Homo sapiens OX=9606 GN=TPR PE=1 SV=3 4.53 2847.6 - 949922 - - - 3.3254 - 1.734 0.184 - 185.8 1 2 0 0.0043 11 0 0 0 2.19E+07 1.31E+07 - - - 1.8877 1 221125_WJC_METTL3_EV_vs_WT_F04.16067.16067.3 2.33E-06 13/40 K.KFDILVTTPNR.L sp|Q9Y2R4|DDX52_HUMAN 1 1302.7296 0.17 49806 16067 3 1302.729181 435.2505 Probable ATP-dependent RNA helicase DDX52 OS=Homo sapiens OX=9606 GN=DDX52 PE=1 SV=3 8.75 2847.8 - 923560 - - - -0.3109 - 2.777 0.48 - 394 1 2 0 -0.0004 11 0 0 0 5.49E+06 3.14E+07 - - - 6.793 0.9991 221125_WJC_METTL3_EV_vs_WT_F04.16071.16071.3 7.26E-06 15/52 K.QMADTGKLNTLLQR.A "sp|Q00839|HNRPU_HUMAN,tr|A0A1W2PQL0|A0A1W2PQL0_HUMAN,tr|A0A1W2PPE9|A0A1W2PPE9_HUMAN,tr|A0A1W2PPL4|A0A1W2PPL4_HUMAN,tr|A0A1W2PQ74|A0A1W2PQ74_HUMAN,tr|Q5RI18|Q5RI18_HUMAN,tr|A0A1W2PP35|A0A1W2PP35_HUMAN,tr|A0A1W2PPS1|A0A1W2PPS1_HUMAN,tr|A0A1W2PRZ7|A0A1W2PRZ7_HUMAN,tr|A0A1W2PPH7|A0A1W2PPH7_HUMAN,tr|A0A1W2PQD4|A0A1W2PQD4_HUMAN,tr|A0A1W2PP34|A0A1W2PP34_HUMAN,tr|A0A1X7SBS1|A0A1X7SBS1_HUMAN" 13 1587.8403 0.66 49810 16071 3 1587.835908 530.2874 Heterogeneous nuclear ribonucleoprotein U OS=Homo sapiens OX=9606 GN=HNRNPU PE=1 SV=6 8.75 2848.3 - 826140 - - - -2.7509 - 2.285 0.444 - 288.5 1 2 1 -0.0044 14 0 0 0 2.86E+06 4.33E+06 - - - 5.685 0.9998 221125_WJC_METTL3_EV_vs_WT_F04.16072.16072.2 0.0022 13/22 K.ASGPPVSELITK[136.11].A "sp|P10412|H14_HUMAN,sp|P16403|H12_HUMAN,sp|P16402|H13_HUMAN" 3 1205.6747 0.8 49811 16072 2 1205.67495 603.8446 Histone H1.4 OS=Homo sapiens OX=9606 GN=H1-4 PE=1 SV=2 6.05 2848.4 - 801960 - - - 0.204 - 2.234 0.367 - 560.1 1 2 0 0.0002 12 0 0 0 1.70E+07 2.11E+07 - - - 3.8665 0.9998 221125_WJC_METTL3_EV_vs_WT_F04.16076.16076.3 0.00262 Dec-36 R.KSPLTLEDFK.F "sp|Q16512|PKN1_HUMAN,tr|K7EL10|K7EL10_HUMAN" 2 1176.639 5.71 49815 16076 3 1176.637786 393.2203 Serine\threonine-protein kinase N1 OS=Homo sapiens OX=9606 GN=PKN1 PE=1 SV=2 6.07 2848.9 - 418175 - - - -1.0657 - 1.846 0.373 - 194.3 1 2 0 -0.0013 10 0 0 0 1.17E+07 2.05E+06 - - - 4.4885 1 221125_WJC_METTL3_EV_vs_WT_F04.16080.16080.3 6.64E-10 19/60 R.GIYAYGFEKPSAIQQR.A "sp|Q14240|IF4A2_HUMAN,sp|P38919|IF4A3_HUMAN,sp|P60842|IF4A1_HUMAN,tr|J3KTB5|J3KTB5_HUMAN,tr|J3KT04|J3KT04_HUMAN,tr|J3KS93|J3KS93_HUMAN,tr|E7EMV8|E7EMV8_HUMAN,tr|J3KT12|J3KT12_HUMAN,tr|J3QKZ9|J3QKZ9_HUMAN,tr|J3QS69|J3QS69_HUMAN,tr|I3L3H2|I3L3H2_HUMAN,tr|J3QL43|J3QL43_HUMAN,tr|F8WE11|F8WE11_HUMAN,tr|E7EQG2|E7EQG2_HUMAN,tr|J3KS25|J3KS25_HUMAN,tr|E9PBH4|E9PBH4_HUMAN,tr|J3QLN6|J3QLN6_HUMAN,tr|J3QQP0|J3QQP0_HUMAN,tr|J3QR64|J3QR64_HUMAN,tr|J3KSN7|J3KSN7_HUMAN" 20 1826.9315 1.53 49817 16080 3 1826.932306 609.9845 Eukaryotic initiation factor 4A-II OS=Homo sapiens OX=9606 GN=EIF4A2 PE=1 SV=2 8.5 2849.4 - 1.85E+07 - - - 0.4226 - 3.366 0.652 - 360.3 1 2 0 0.0008 16 0 0 0 2.91E+08 1.90E+08 - - - 8.9232 1 221125_WJC_METTL3_EV_vs_WT_F04.16081.16081.3 3.24E-05 18/60 R.GIYAYGFEK[136.11]PSAIQQR[166.11].A "sp|Q14240|IF4A2_HUMAN,sp|P38919|IF4A3_HUMAN,sp|P60842|IF4A1_HUMAN,tr|J3KTB5|J3KTB5_HUMAN,tr|J3KT04|J3KT04_HUMAN,tr|J3KS93|J3KS93_HUMAN,tr|E7EMV8|E7EMV8_HUMAN,tr|J3KT12|J3KT12_HUMAN,tr|J3QKZ9|J3QKZ9_HUMAN,tr|J3QS69|J3QS69_HUMAN,tr|I3L3H2|I3L3H2_HUMAN,tr|J3QL43|J3QL43_HUMAN,tr|F8WE11|F8WE11_HUMAN,tr|E7EQG2|E7EQG2_HUMAN,tr|J3KS25|J3KS25_HUMAN,tr|E9PBH4|E9PBH4_HUMAN,tr|J3QLN6|J3QLN6_HUMAN,tr|J3QQP0|J3QQP0_HUMAN,tr|J3QR64|J3QR64_HUMAN,tr|J3KSN7|J3KSN7_HUMAN" 20 1844.954 1.52 49818 16081 3 1844.953923 615.9919 Eukaryotic initiation factor 4A-II OS=Homo sapiens OX=9606 GN=EIF4A2 PE=1 SV=2 8.5 2849.4 - 1.63E+07 - - - -0.0439 - 3.57 0.608 - 305.2 1 2 0 -0.0001 16 0 0 0 2.89E+08 1.90E+08 - - - 8.5838 1 221125_WJC_METTL3_EV_vs_WT_F04.16082.16082.3 9.92E-11 16/52 K.DPEGFVGHPVNAFK.L sp|P13674|P4HA1_HUMAN 1 1512.7361 1.73 49819 16082 3 1512.735097 505.2527 Prolyl 4-hydroxylase subunit alpha-1 OS=Homo sapiens OX=9606 GN=P4HA1 PE=1 SV=2 5.32 2849.4 - 6.25E+06 - - - -0.6815 - 3.28 0.631 - 355.1 1 2 0 -0.001 14 0 0 0 9.19E+07 5.31E+07 - - - 8.7315 0.9998 221125_WJC_METTL3_EV_vs_WT_F04.16084.16084.2 3.05E-05 13/26 K.NGIAGSSLPPPPIK[136.11].H sp|Q9Y5A9|YTHD2_HUMAN 1 1354.77 1.52 49821 16084 2 1354.767895 678.3923 YTH domain-containing family protein 2 OS=Homo sapiens OX=9606 GN=YTHDF2 PE=1 SV=2 8.75 2849.6 - 2.30E+06 - - - -1.5545 - 2.285 0.563 - 581.2 1 2 0 -0.0021 14 0 0 0 3.27E+07 2.16E+07 - - - 5.2724 1 221125_WJC_METTL3_EV_vs_WT_F04.16086.16086.3 2.93E-06 Dec-52 R.LYQQHGAGLFDVTR.G "sp|O14773|TPP1_HUMAN,tr|A0A804HJ17|A0A804HJ17_HUMAN,tr|A0A2R8YGD1|A0A2R8YGD1_HUMAN,tr|A0A2R8Y7U1|A0A2R8Y7U1_HUMAN,tr|A0A2R8YD45|A0A2R8YD45_HUMAN" 5 1603.8107 1.9 49823 16086 3 1603.811018 535.6108 Tripeptidyl-peptidase 1 OS=Homo sapiens OX=9606 GN=TPP1 PE=1 SV=2 6.74 2849.7 - 1.64E+06 - - - 0.2045 - 2.18 0.501 - 151.7 1 2 0 0.0003 14 0 0 0 9.86E+06 5.20E+06 - - - 6.1966 1 221125_WJC_METTL3_EV_vs_WT_F04.16087.16087.3 9.64E-06 15/48 R.ADTLDPALLR[166.11]PGR[166.11].L sp|P43686|PRS6B_HUMAN 1 1413.7843 1.59 49824 16087 3 1413.782394 472.2687 26S proteasome regulatory subunit 6B OS=Homo sapiens OX=9606 GN=PSMC4 PE=1 SV=2 6.01 2849.8 - 1.07E+06 - - - -1.3503 - 2.708 0.481 - 192.2 1 2 0 -0.0019 13 0 0 0 1.64E+07 1.03E+07 - - - 6.6032 0.9991 221125_WJC_METTL3_EV_vs_WT_F04.16088.16088.2 1.59E-05 22-Dec K.ASGPPVSELITK.A "sp|P10412|H14_HUMAN,sp|P16403|H12_HUMAN,sp|P16402|H13_HUMAN" 3 1197.6605 1.11 49825 16088 2 1197.662241 599.8375 Histone H1.4 OS=Homo sapiens OX=9606 GN=H1-4 PE=1 SV=2 6.05 2849.9 - 976297 - - - 1.4503 - 2.057 0.273 - 444.5 1 2 0 0.0017 12 0 0 0 8.36E+06 7.52E+06 - - - 2.9546 0.9999 221125_WJC_METTL3_EV_vs_WT_F04.16089.16089.3 0.00168 Sep-48 K.WNVSRPSLLADSK.D sp|Q6P2Q9|PRP8_HUMAN 1 1471.7783 0.84 49826 16089 3 1471.778888 491.6001 Pre-mRNA-processing-splicing factor 8 OS=Homo sapiens OX=9606 GN=PRPF8 PE=1 SV=2 8.75 2850.1 - 856850 - - - 0.3812 - 2.232 0.38 - 99.1 1 2 0 0.0006 13 0 0 0 3.49E+06 4.18E+06 - - - 4.9534 0.9996 221125_WJC_METTL3_EV_vs_WT_F04.16090.16090.2 5.27E-05 24-Nov R.VQDLIEGHLTASQ.- sp|Q8WXD5|GEMI6_HUMAN 1 1409.7151 - 49827 16090 2 1409.711698 705.8648 Gem-associated protein 6 OS=Homo sapiens OX=9606 GN=GEMIN6 PE=1 SV=1 4.35 2850.2 - 734883 - - - -2.3835 - 2.513 0.459 - 414.3 1 2 0 -0.0034 13 0 0 0 - - - - - 4.7951 0.9993 221125_WJC_METTL3_EV_vs_WT_F04.16091.16091.3 0.000306 Dec-32 K.LVK[136.11]EEVFWR[166.11].N sp|Q96A49|SYAP1_HUMAN 1 1222.6829 1.28 49828 16091 3 1222.680867 408.5682 Synapse-associated protein 1 OS=Homo sapiens OX=9606 GN=SYAP1 PE=1 SV=1 6.14 2850.3 - 674300 - - - -1.6742 - 2.175 0.388 - 215.7 1 2 1 -0.002 9 0 0 0 1.57E+07 1.23E+07 - - - 5.2071 1 221125_WJC_METTL3_EV_vs_WT_F04.16093.16093.2 1.55E-10 19/30 R.GIYAYGFEKPSAIQQR.A "sp|Q14240|IF4A2_HUMAN,sp|P38919|IF4A3_HUMAN,sp|P60842|IF4A1_HUMAN,tr|J3KTB5|J3KTB5_HUMAN,tr|J3KT04|J3KT04_HUMAN,tr|J3KS93|J3KS93_HUMAN,tr|E7EMV8|E7EMV8_HUMAN,tr|J3KT12|J3KT12_HUMAN,tr|J3QKZ9|J3QKZ9_HUMAN,tr|J3QS69|J3QS69_HUMAN,tr|I3L3H2|I3L3H2_HUMAN,tr|J3QL43|J3QL43_HUMAN,tr|F8WE11|F8WE11_HUMAN,tr|E7EQG2|E7EQG2_HUMAN,tr|J3KS25|J3KS25_HUMAN,tr|E9PBH4|E9PBH4_HUMAN,tr|J3QLN6|J3QLN6_HUMAN,tr|J3QQP0|J3QQP0_HUMAN,tr|J3QR64|J3QR64_HUMAN,tr|J3KSN7|J3KSN7_HUMAN" 20 1826.9315 1.52 49830 16093 2 1826.935276 914.473 Eukaryotic initiation factor 4A-II OS=Homo sapiens OX=9606 GN=EIF4A2 PE=1 SV=2 8.5 2850.6 - 558411 - - - 2.0482 - 3.427 0.6 - 991.1 1 2 0 0.0037 16 0 0 0 8.52E+06 5.59E+06 - - - 6.4996 0.9973 221125_WJC_METTL3_EV_vs_WT_F04.16094.16094.3 0.0465 Dec-36 R.RVLDELTLAR.A "sp|Q04695|K1C17_HUMAN,sp|P02533|K1C14_HUMAN,sp|P08727|K1C19_HUMAN,sp|P08779|K1C16_HUMAN,sp|P19012|K1C15_HUMAN,tr|C9JM50|C9JM50_HUMAN,tr|C9JTG5|C9JTG5_HUMAN,tr|F5GWP8|F5GWP8_HUMAN,tr|K7EMS3|K7EMS3_HUMAN,tr|A8MT21|A8MT21_HUMAN" 10 1184.6877 1324.16 49831 16094 3 1184.683243 395.9032 "Keratin, type I cytoskeletal 17 OS=Homo sapiens OX=9606 GN=KRT17 PE=1 SV=2" 6.07 2850.7 - 482334 - - - -3.7799 - 2.063 0.298 - 195.4 1 2 0 -0.0045 10 0 0 0 4.26E+08 3.22E+05 - - - 3.976 0.9841 221125_WJC_METTL3_EV_vs_WT_F04.16095.16095.2 4.66E-05 30-Sep F.NMNAPVPPVNEPETLK.Q "sp|Q14444|CAPR1_HUMAN,tr|G3V153|G3V153_HUMAN" 2 1748.8767 0.65 49832 16095 2 1748.875254 875.4456 Caprin-1 OS=Homo sapiens OX=9606 GN=CAPRIN1 PE=1 SV=2 4.53 2850.8 - 427853 - - - -0.8388 - 1.747 0.466 - 169.1 1 1 0 -0.0015 16 0 0 0 6.61E+06 1.02E+07 - - - 3.854 0.9928 221125_WJC_METTL3_EV_vs_WT_F04.16096.16096.2 1.43E-06 30-Oct F.NMNAPVPPVNEPETLK[136.11].Q "sp|Q14444|CAPR1_HUMAN,tr|G3V153|G3V153_HUMAN" 2 1756.8909 0.63 49833 16096 2 1756.889184 879.4527 Caprin-1 OS=Homo sapiens OX=9606 GN=CAPRIN1 PE=1 SV=2 4.53 2851 - 392952 - - - -0.9887 - 2.027 0.599 - 209.8 1 1 0 -0.0017 16 0 0 0 6.61E+06 1.05E+07 - - - 5.2018 1 221125_WJC_METTL3_EV_vs_WT_F04.16097.16097.2 9.97E-10 15/24 R.YPTGESYQDLVQR[166.11].L "sp|Q16875|F263_HUMAN,tr|A0A1W2PR17|A0A1W2PR17_HUMAN,tr|Q5W015|Q5W015_HUMAN,tr|F2Z2I2|F2Z2I2_HUMAN,tr|Q5VX20|Q5VX20_HUMAN" 5 1564.7397 4.23 49834 16097 2 1564.742082 783.3771 "6-phosphofructo-2-kinase\fructose-2,6-bisphosphatase 3 OS=Homo sapiens OX=9606 GN=PFKFB3 PE=1 SV=1" 4.37 2851.1 - 312628 - - - 1.5178 - 3.029 0.711 - 996.1 1 2 0 0.0024 13 0 0 0 1.01E+08 2.38E+07 - - - 7.136 0.9998 221125_WJC_METTL3_EV_vs_WT_F04.16098.16098.2 1.86E-06 24-Dec K.AALLNQHYQVNFK.G "sp|P07814|SYEP_HUMAN,tr|V9GYZ6|V9GYZ6_HUMAN" 2 1544.81 1 49835 16098 2 1544.806964 773.4123 Bifunctional glutamate\proline--tRNA ligase OS=Homo sapiens OX=9606 GN=EPRS1 PE=1 SV=5 8.64 2851.2 - 276887 - - - -1.9407 - 2.229 0.575 - 323.9 1 2 0 -0.003 13 0 0 0 1.98E+06 1.98E+06 - - - 5.3442 0.9999 221125_WJC_METTL3_EV_vs_WT_F04.16101.16101.2 4.47E-06 13/24 K.QSLEASLAETEGR.Y "sp|P13645|K1C10_HUMAN,tr|A0A1B0GVI3|A0A1B0GVI3_HUMAN" 2 1389.6736 999 49837 16101 2 1389.671747 695.8441 "Keratin, type I cytoskeletal 10 OS=Homo sapiens OX=9606 GN=KRT10 PE=1 SV=6" 4.25 2851.6 - 4.14E+06 - - - -1.3241 - 2.642 0.552 - 713.7 1 2 0 -0.0018 13 0 0 0 6.60E+08 0.00E+00 - - - 5.611 0.9998 221125_WJC_METTL3_EV_vs_WT_F04.16103.16103.3 1.94E-07 20/40 K.FAAQELIEVK[136.11]R[166.11].G "sp|Q86U44|MTA70_HUMAN,tr|F5H6D8|F5H6D8_HUMAN,tr|H0YFV6|H0YFV6_HUMAN,tr|B4DTN4|B4DTN4_HUMAN" 4 1320.7521 0.01 49839 16103 3 1320.751516 441.258 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 6.14 2851.7 - 1.87E+07 - - - -0.4089 - 2.829 0.276 - 423.2 1 2 0 -0.0005 11 0 0 0 2.36E+07 4.19E+09 - - - 4.5712 1 221125_WJC_METTL3_EV_vs_WT_F04.16104.16104.2 9.65E-10 15/30 L.GGGFSSGGFSGGSFSR.G "sp|P13645|K1C10_HUMAN,tr|A0A1B0GVI3|A0A1B0GVI3_HUMAN" 2 1449.6273 999 49840 16104 2 1449.627518 725.8209 "Keratin, type I cytoskeletal 10 OS=Homo sapiens OX=9606 GN=KRT10 PE=1 SV=6" 9.75 2851.8 - 1.45E+07 - - - 0.1462 - 2.872 0.654 - 518.5 1 1 0 0.0002 16 0 0 0 1.00E+08 0.00E+00 - - - 6.4652 1 221125_WJC_METTL3_EV_vs_WT_F04.16105.16105.2 3.60E-11 17/24 R.YPTGESYQDLVQR.L "sp|Q16875|F263_HUMAN,tr|A0A1W2PR17|A0A1W2PR17_HUMAN,tr|Q5W015|Q5W015_HUMAN,tr|F2Z2I2|F2Z2I2_HUMAN,tr|Q5VX20|Q5VX20_HUMAN" 5 1554.7314 2.01 49841 16105 2 1554.73158 778.373 "6-phosphofructo-2-kinase\fructose-2,6-bisphosphatase 3 OS=Homo sapiens OX=9606 GN=PFKFB3 PE=1 SV=1" 4.37 2851.9 - 2.60E+06 - - - 0.092 - 3.106 0.575 - 1302.5 1 2 0 0.0001 13 0 0 0 1.02E+08 5.09E+07 - - - 6.1966 1 221125_WJC_METTL3_EV_vs_WT_F04.16106.16106.3 1.38E-06 13/44 R.QHQMQLVDSIVR.Q sp|P12270|TPR_HUMAN 1 1452.7507 4.43 49842 16106 3 1452.750755 485.2575 Nucleoprotein TPR OS=Homo sapiens OX=9606 GN=TPR PE=1 SV=3 6.74 2852 - 965002 - - - 0.0158 - 2.669 0.496 - 314.9 1 2 0 0 12 0 0 0 9.30E+06 2.10E+06 - - - 6.791 0.9998 221125_WJC_METTL3_EV_vs_WT_F04.16108.16108.3 1.02E-07 18/56 K.DVDEAYMNKVELESR.L "sp|P05787|K2C8_HUMAN,tr|F8VUG2|F8VUG2_HUMAN,tr|F8VP67|F8VP67_HUMAN,tr|F8W1U3|F8W1U3_HUMAN" 4 1796.8251 1.65 49844 16108 3 1796.820264 599.949 "Keratin, type II cytoskeletal 8 OS=Homo sapiens OX=9606 GN=KRT8 PE=1 SV=7" 4.18 2852.2 - 860732 - - - -2.6797 - 2.513 0.612 - 301.9 1 2 1 -0.0048 15 0 0 0 7.61E+06 4.62E+06 - - - 7.7663 0.9999 221125_WJC_METTL3_EV_vs_WT_F04.16109.16109.2 0.000764 15/30 R.GIYAYGFEK[136.11]PSAIQQR[166.11].A "sp|Q14240|IF4A2_HUMAN,sp|P38919|IF4A3_HUMAN,sp|P60842|IF4A1_HUMAN,tr|J3KTB5|J3KTB5_HUMAN,tr|J3KT04|J3KT04_HUMAN,tr|J3KS93|J3KS93_HUMAN,tr|E7EMV8|E7EMV8_HUMAN,tr|J3KT12|J3KT12_HUMAN,tr|J3QKZ9|J3QKZ9_HUMAN,tr|J3QS69|J3QS69_HUMAN,tr|I3L3H2|I3L3H2_HUMAN,tr|J3QL43|J3QL43_HUMAN,tr|F8WE11|F8WE11_HUMAN,tr|E7EQG2|E7EQG2_HUMAN,tr|J3KS25|J3KS25_HUMAN,tr|E9PBH4|E9PBH4_HUMAN,tr|J3QLN6|J3QLN6_HUMAN,tr|J3QQP0|J3QQP0_HUMAN,tr|J3QR64|J3QR64_HUMAN,tr|J3KSN7|J3KSN7_HUMAN" 20 1844.954 1.52 49845 16109 2 1844.954278 923.4843 Eukaryotic initiation factor 4A-II OS=Homo sapiens OX=9606 GN=EIF4A2 PE=1 SV=2 8.5 2852.4 - 852569 - - - 0.1485 - 2.758 0.556 - 586.5 1 2 0 0.0003 16 0 0 0 8.52E+06 5.59E+06 - - - 5.6417 0.9956 221125_WJC_METTL3_EV_vs_WT_F04.16113.16113.3 0.0314 Oct-32 K.QLEDWLHSK.S "sp|Q92878|RAD50_HUMAN,tr|E7EN38|E7EN38_HUMAN,tr|A0A494BZX5|A0A494BZX5_HUMAN,tr|H7C0P8|H7C0P8_HUMAN,tr|A0A494C1B7|A0A494C1B7_HUMAN,tr|A0A494C122|A0A494C122_HUMAN,tr|A0A1W2PQ90|A0A1W2PQ90_HUMAN" 7 1154.572 0.84 49849 16113 3 1154.570125 385.8646 DNA repair protein RAD50 OS=Homo sapiens OX=9606 GN=RAD50 PE=1 SV=1 5.32 2852.9 - 600850 - - - -1.6439 - 1.573 0.236 - 137.7 1 2 0 -0.0019 9 0 0 0 3.13E+06 3.74E+06 - - - 2.5358 0.9833 221125_WJC_METTL3_EV_vs_WT_F04.16115.16115.2 8.04E-05 16-Oct A.AQELIEVK[136.11]R[166.11].G "sp|Q86U44|MTA70_HUMAN,tr|F5H6D8|F5H6D8_HUMAN,tr|H0YFV6|H0YFV6_HUMAN,tr|B4DTN4|B4DTN4_HUMAN" 4 1102.6465 0.01 49851 16115 2 1102.648799 552.3305 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 6.19 2853.1 - 457852 - - - 2.0596 - 2.161 0.492 - 626.6 1 1 0 0.0023 9 0 0 0 1.13E+06 9.73E+07 - - - 4.9035 0.9842 221125_WJC_METTL3_EV_vs_WT_F04.16118.16118.3 7.98E-08 Dec-48 K.WKDTDEADLVLAK.E sp|P45973|CBX5_HUMAN 1 1502.7617 1.08 49853 16118 3 1502.765401 501.9278 Chromobox protein homolog 5 OS=Homo sapiens OX=9606 GN=CBX5 PE=1 SV=1 4.23 2853.5 - 3.91E+06 - - - 2.4801 - 2.555 0.183 - 272.3 1 2 1 0.0037 13 0 0 0 2.82E+07 2.62E+07 - - - 3.1226 0.9974 221125_WJC_METTL3_EV_vs_WT_F04.16121.16121.3 1.97E-05 15/48 K.ELVEFAQDDDRLR.E sp|Q14677|EPN4_HUMAN 1 1604.7794 1.71 49855 16121 3 1604.771792 535.9338 Clathrin interactor 1 OS=Homo sapiens OX=9606 GN=CLINT1 PE=1 SV=1 4.11 2853.8 - 2.69E+06 - - - -4.772 - 2.253 0.482 - 459.9 1 2 1 -0.0077 13 0 0 0 3.05E+08 1.79E+08 - - - 6.114 0.9985 221125_WJC_METTL3_EV_vs_WT_F04.16122.16122.3 0.161 15/40 K.FAAQELIEVKR[166.11].G "sp|Q86U44|MTA70_HUMAN,tr|F5H6D8|F5H6D8_HUMAN,tr|H0YFV6|H0YFV6_HUMAN,tr|B4DTN4|B4DTN4_HUMAN" 4 1312.7379 - 49856 16122 3 1312.740829 438.5866 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 6.14 2853.8 - 1.98E+06 - - - 2.2647 - 2.192 0.256 - 144.1 1 2 0 0.003 11 0 0 0 - - - - - 3.6228 0.9994 221125_WJC_METTL3_EV_vs_WT_F04.16128.16128.2 7.68E-05 20-Dec K.QQISLATQMVR[166.11].M "sp|P48643|TCPE_HUMAN,tr|E9PCA1|E9PCA1_HUMAN,tr|B7ZAR1|B7ZAR1_HUMAN,tr|E7ENZ3|E7ENZ3_HUMAN" 4 1283.6895 0.37 49862 16128 2 1283.691968 642.852 T-complex protein 1 subunit epsilon OS=Homo sapiens OX=9606 GN=CCT5 PE=1 SV=1 9.75 2854.3 - 1.07E+06 - - - 1.9023 - 2.038 0.371 - 602.2 1 2 0 0.0024 11 0 0 0 6.79E+06 1.84E+07 - - - 3.7065 0.9997 221125_WJC_METTL3_EV_vs_WT_F04.16132.16132.2 0.000516 18-Nov R.RVLDELTLAR.A "sp|Q04695|K1C17_HUMAN,sp|P02533|K1C14_HUMAN,sp|P08727|K1C19_HUMAN,sp|P08779|K1C16_HUMAN,sp|P19012|K1C15_HUMAN,tr|C9JM50|C9JM50_HUMAN,tr|C9JTG5|C9JTG5_HUMAN,tr|F5GWP8|F5GWP8_HUMAN,tr|K7EMS3|K7EMS3_HUMAN,tr|A8MT21|A8MT21_HUMAN" 10 1184.6877 38.98 49866 16132 2 1184.686195 593.3511 "Keratin, type I cytoskeletal 17 OS=Homo sapiens OX=9606 GN=KRT17 PE=1 SV=2" 6.07 2854.8 - 870465 - - - -1.2881 - 1.954 0.417 - 204.9 1 2 0 -0.0015 10 0 0 0 4.03E+07 1.03E+06 - - - 3.9903 0.9985 221125_WJC_METTL3_EV_vs_WT_F04.16134.16134.3 0.0226 Oct-48 R.ADTLDPALLRPGR.L sp|P43686|PRS6B_HUMAN 1 1393.7678 1.63 49868 16134 3 1393.768697 465.5965 26S proteasome regulatory subunit 6B OS=Homo sapiens OX=9606 GN=PSMC4 PE=1 SV=2 6.01 2855.1 - 719451 - - - 0.6701 - 1.861 0.253 - 88.1 1 2 0 0.0009 13 0 0 0 1.68E+07 1.03E+07 - - - 3.0445 0.9088 221125_WJC_METTL3_EV_vs_WT_F04.16138.16138.2 0.00114 Jun-32 R.LLEGEDAHLSSSQFSSG.S sp|P02533|K1C14_HUMAN 1 1762.801 - 49872 16138 2 1762.795674 882.4078 "Keratin, type I cytoskeletal 14 OS=Homo sapiens OX=9606 GN=KRT14 PE=1 SV=4" 4.13 2855.6 - 493053 - - - -3.006 - 1.398 0.47 - 63.6 1 1 0 -0.0053 17 0 0 0 - - - - - 3.3345 1 221125_WJC_METTL3_EV_vs_WT_F04.16139.16139.3 5.73E-07 15/44 R.QHQMQLVDSIVR[166.11].Q sp|P12270|TPR_HUMAN 1 1462.759 4.73 49873 16139 3 1462.756859 488.5936 Nucleoprotein TPR OS=Homo sapiens OX=9606 GN=TPR PE=1 SV=3 6.74 2855.7 - 489169 - - - -1.465 - 2.527 0.469 - 347.1 1 2 0 -0.0021 12 0 0 0 9.94E+06 2.10E+06 - - - 6.3379 1 221125_WJC_METTL3_EV_vs_WT_F04.16141.16141.2 1.80E-08 16/26 K.AEAGAGSATEFQFR.G "sp|Q9NQ39|RS10L_HUMAN,sp|P46783|RS10_HUMAN" 2 1440.6634 2.62 49874 16141 2 1440.66333 721.339 Putative 40S ribosomal protein S10-like OS=Homo sapiens OX=9606 GN=RPS10P5 PE=5 SV=1 4.53 2856 - 2.10E+06 - - - -0.0187 - 3.425 0.556 - 1085.1 1 2 0 0 14 0 0 0 3.38E+07 1.29E+07 - - - 6.237 1 221125_WJC_METTL3_EV_vs_WT_F04.16142.16142.3 1.01E-06 14/72 K.NLPPSGAVPVTGIPPHVVK[136.11].V "sp|Q13283|G3BP1_HUMAN,tr|A0A7I2V5M7|A0A7I2V5M7_HUMAN,tr|A0A7I2YQM1|A0A7I2YQM1_HUMAN,tr|A0A7P0P2U7|A0A7P0P2U7_HUMAN,tr|A0A7I2YQU8|A0A7I2YQU8_HUMAN,tr|A0A7I2V548|A0A7I2V548_HUMAN,tr|A0A7I2V651|A0A7I2V651_HUMAN,tr|A0A7I2V4D8|A0A7I2V4D8_HUMAN,tr|A0A7I2YQN9|A0A7I2YQN9_HUMAN" 9 1886.0869 1.36 49875 16142 3 1886.085592 629.7029 Ras GTPase-activating protein-binding protein 1 OS=Homo sapiens OX=9606 GN=G3BP1 PE=1 SV=1 8.76 2856 - 2.09E+06 - - - -0.703 - 2.322 0.508 - 143.4 1 2 0 -0.0013 19 0 0 0 5.93E+07 4.36E+07 - - - 6.273 0.9999 221125_WJC_METTL3_EV_vs_WT_F04.16143.16143.2 4.45E-07 14/20 K.FAAQELIEVK[136.11]R[166.11].G "sp|Q86U44|MTA70_HUMAN,tr|F5H6D8|F5H6D8_HUMAN,tr|H0YFV6|H0YFV6_HUMAN,tr|B4DTN4|B4DTN4_HUMAN" 4 1320.7521 0 49876 16143 2 1320.751056 661.3833 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 6.14 2856.1 - 1.61E+07 - - - -0.7571 - 2.897 0.47 - 1009.3 1 2 0 -0.001 11 0 0 0 6.90E+05 3.37E+08 - - - 5.3896 0.9999 221125_WJC_METTL3_EV_vs_WT_F04.16144.16144.3 6.03E-06 Dec-48 K.ELVEFAQDDDR[166.11]LR[166.11].E sp|Q14677|EPN4_HUMAN 1 1624.796 1.71 49877 16144 3 1624.795186 542.6059 Clathrin interactor 1 OS=Homo sapiens OX=9606 GN=CLINT1 PE=1 SV=1 4.11 2856.1 - 8.81E+06 - - - -0.4948 - 2.456 0.515 - 282.7 1 2 1 -0.0008 13 0 0 0 3.05E+08 1.79E+08 - - - 6.7177 0.994 221125_WJC_METTL3_EV_vs_WT_F04.16146.16146.2 4.14E-05 18-Oct F.AAQELIEVK[136.11]R[166.11].G "sp|Q86U44|MTA70_HUMAN,tr|F5H6D8|F5H6D8_HUMAN,tr|H0YFV6|H0YFV6_HUMAN,tr|B4DTN4|B4DTN4_HUMAN" 4 1173.6836 0 49879 16146 2 1173.682842 587.8491 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 6.19 2856.2 - 4.27E+06 - - - -0.6816 - 2.545 0.501 - 563.2 1 1 0 -0.0008 10 0 0 0 1.86E+05 8.87E+07 - - - 5.3486 1 221125_WJC_METTL3_EV_vs_WT_F04.16147.16147.2 1.07E-09 17/30 K.ASLNGADIYSGC[160.03]C[160.03]TLK.L "sp|P14866|HNRPL_HUMAN,tr|B4DVF8|B4DVF8_HUMAN,tr|M0R1W6|M0R1W6_HUMAN,tr|A0A3B3ITJ4|A0A3B3ITJ4_HUMAN,tr|M0QXS5|M0QXS5_HUMAN" 5 1728.7811 1.21 49880 16147 2 1728.779427 865.3978 Heterogeneous nuclear ribonucleoprotein L OS=Homo sapiens OX=9606 GN=HNRNPL PE=1 SV=2 5.86 2856.3 - 3.66E+06 - - - -0.9712 - 3.241 0.617 - 862.8 1 2 0 -0.0017 16 0 0 0 7.30E+07 6.05E+07 - - - 6.4886 1 221125_WJC_METTL3_EV_vs_WT_F04.16149.16149.2 1.42E-09 16/30 K.ASLNGADIYSGC[160.03]C[160.03]TLK[136.11].L "sp|P14866|HNRPL_HUMAN,tr|B4DVF8|B4DVF8_HUMAN,tr|M0R1W6|M0R1W6_HUMAN,tr|A0A3B3ITJ4|A0A3B3ITJ4_HUMAN,tr|M0QXS5|M0QXS5_HUMAN" 5 1736.7953 1.21 49882 16149 2 1736.792578 869.4049 Heterogeneous nuclear ribonucleoprotein L OS=Homo sapiens OX=9606 GN=HNRNPL PE=1 SV=2 5.86 2856.4 - 3.15E+06 - - - -1.5707 - 3.102 0.699 - 625.8 1 2 0 -0.0027 16 0 0 0 7.30E+07 6.05E+07 - - - 6.9861 1 221125_WJC_METTL3_EV_vs_WT_F04.16150.16150.3 1.78E-05 17/52 K.LPETNLFETEETRK.L sp|Q15046|SYK_HUMAN 1 1705.8523 0.68 49883 16150 3 1705.852911 569.6247 Lysine--tRNA ligase OS=Homo sapiens OX=9606 GN=KARS1 PE=1 SV=3 4.49 2856.4 - 2.83E+06 - - - 0.3699 - 3.301 0.567 - 345.8 1 2 0 0.0006 14 0 0 0 1.93E+07 2.86E+07 - - - 8.035 0.9999 221125_WJC_METTL3_EV_vs_WT_F04.16151.16151.3 0.000134 13/48 K.VFIQHITLSDEER[166.11].K "sp|Q14527|HLTF_HUMAN,tr|H7C5K0|H7C5K0_HUMAN,tr|A0A0C4DGA6|A0A0C4DGA6_HUMAN" 3 1595.8183 1.12 49884 16151 3 1595.817953 532.9467 Helicase-like transcription factor OS=Homo sapiens OX=9606 GN=HLTF PE=1 SV=2 4.65 2856.5 - 1.74E+06 - - - -0.2118 - 2.23 0.462 - 212.4 1 2 0 -0.0003 13 0 0 0 2.96E+07 2.65E+07 - - - 5.8652 1 221125_WJC_METTL3_EV_vs_WT_F04.16152.16152.3 7.41E-05 17/52 R.QENVLVIC[160.03]HQAVLR.C "sp|Q16875|F263_HUMAN,tr|A0A1W2PR17|A0A1W2PR17_HUMAN,tr|Q5W015|Q5W015_HUMAN,tr|F2Z2I2|F2Z2I2_HUMAN,tr|H0Y483|H0Y483_HUMAN,tr|Q5VX20|Q5VX20_HUMAN" 6 1677.8985 2.99 49885 16152 3 1677.897883 560.3068 "6-phosphofructo-2-kinase\fructose-2,6-bisphosphatase 3 OS=Homo sapiens OX=9606 GN=PFKFB3 PE=1 SV=1" 6.74 2856.6 - 1.30E+06 - - - -0.3433 - 3.202 0.518 - 693.6 1 2 0 -0.0006 14 0 0 0 4.22E+07 1.41E+07 - - - 7.4078 0.9986 221125_WJC_METTL3_EV_vs_WT_F04.16153.16153.3 0.0151 Oct-44 K.HEELMLGDPC[160.03]LK.D "sp|P07814|SYEP_HUMAN,tr|V9GYZ6|V9GYZ6_HUMAN" 2 1440.6741 1.59 49886 16153 3 1440.671972 481.232 Bifunctional glutamate\proline--tRNA ligase OS=Homo sapiens OX=9606 GN=EPRS1 PE=1 SV=5 4.65 2856.7 - 1.05E+06 - - - -1.4924 - 1.498 0.322 - 59.7 1 2 0 -0.0022 12 0 0 0 1.01E+07 6.36E+06 - - - 3.2496 0.9952 221125_WJC_METTL3_EV_vs_WT_F04.16154.16154.2 0.00974 14/24 K.ELVEFAQDDDRLR.E sp|Q14677|EPN4_HUMAN 1 1604.7794 1.52 49887 16154 2 1604.776328 803.397 Clathrin interactor 1 OS=Homo sapiens OX=9606 GN=CLINT1 PE=1 SV=1 4.11 2856.8 - 871181 - - - -1.9454 - 2.399 0.371 - 333.5 1 2 1 -0.0031 13 0 0 0 2.27E+07 1.50E+07 - - - 4.0261 0.9976 221125_WJC_METTL3_EV_vs_WT_F04.16155.16155.2 0.00132 24-Sep K.ELVEFAQDDDR[166.11]LR[166.11].E sp|Q14677|EPN4_HUMAN 1 1624.796 1.52 49888 16155 2 1624.796794 813.4053 Clathrin interactor 1 OS=Homo sapiens OX=9606 GN=CLINT1 PE=1 SV=1 4.11 2857 - 552226 - - - 0.4948 - 1.972 0.45 - 100.6 1 2 1 0.0008 13 0 0 0 2.27E+07 1.50E+07 - - - 4.1072 1 221125_WJC_METTL3_EV_vs_WT_F04.16156.16156.3 9.92E-07 18/68 R.TFLR[166.11]PSPEDEAIYGPNTK[136.11].M "sp|Q9UDY2|ZO2_HUMAN,tr|A0A3B3IT83|A0A3B3IT83_HUMAN,tr|A0A2R8YDH4|A0A2R8YDH4_HUMAN,tr|A0A3B3IS03|A0A3B3IS03_HUMAN,tr|A0A3B3ISF1|A0A3B3ISF1_HUMAN,tr|A0A1B0GTW1|A0A1B0GTW1_HUMAN,tr|A0A3B3ISZ5|A0A3B3ISZ5_HUMAN,tr|A0A3B3IRV6|A0A3B3IRV6_HUMAN,tr|A0A3B3IU51|A0A3B3IU51_HUMAN,tr|A0A3B3IRI3|A0A3B3IRI3_HUMAN,tr|A0A3B3ITE1|A0A3B3ITE1_HUMAN" 11 2052.0283 1.75 49889 16156 3 2052.027494 685.0167 Tight junction protein ZO-2 OS=Homo sapiens OX=9606 GN=TJP2 PE=1 SV=2 4.68 2857.1 - 447440 - - - -0.3884 - 3.123 0.475 - 424.6 1 2 0 -0.0008 18 0 0 0 5.17E+06 2.95E+06 - - - 6.6713 0.9996 221125_WJC_METTL3_EV_vs_WT_F04.16158.16158.3 7.10E-05 Dec-32 K.LVKEEVFWR.N sp|Q96A49|SYAP1_HUMAN 1 1204.6604 1.28 49890 16158 3 1204.658891 402.5608 Synapse-associated protein 1 OS=Homo sapiens OX=9606 GN=SYAP1 PE=1 SV=1 6.14 2857.3 - 1.44E+06 - - - -1.2892 - 2.342 0.383 - 267.4 1 2 1 -0.0016 9 0 0 0 1.57E+07 1.23E+07 - - - 5.3744 0.9999 221125_WJC_METTL3_EV_vs_WT_F04.16159.16159.3 0.000397 Dec-64 K.VELVTGEEDEK[136.11]VLYSQR[166.11].V sp|P49792|RBP2_HUMAN 1 2011.0229 -1 49891 16159 3 2011.025103 671.3482 E3 SUMO-protein ligase RanBP2 OS=Homo sapiens OX=9606 GN=RANBP2 PE=1 SV=2 4.25 2857.4 - 260665 - - - 1.1099 - 2.923 0.481 - 113.4 1 2 1 0.0022 17 0 0 0 0.00E+00 0.00E+00 - - - 6.6118 0.9983 221125_WJC_METTL3_EV_vs_WT_F04.16160.16160.3 0.000964 14/60 K.ASLNGADIYSGC[160.03]C[160.03]TLK[136.11].L "sp|P14866|HNRPL_HUMAN,tr|B4DVF8|B4DVF8_HUMAN,tr|M0R1W6|M0R1W6_HUMAN,tr|A0A3B3ITJ4|A0A3B3ITJ4_HUMAN,tr|M0QXS5|M0QXS5_HUMAN" 5 1736.7953 0.41 49892 16160 3 1736.788333 579.939 Heterogeneous nuclear ribonucleoprotein L OS=Homo sapiens OX=9606 GN=HNRNPL PE=1 SV=2 5.86 2857.6 - 781570 - - - -4.0149 - 1.98 0.379 - 157.1 1 2 0 -0.007 16 0 0 0 2.37E+06 5.77E+06 - - - 4.5163 1 221125_WJC_METTL3_EV_vs_WT_F04.16161.16161.3 9.73E-07 15/52 R.QENVLVIC[160.03]HQAVLR[166.11].C "sp|Q16875|F263_HUMAN,tr|A0A1W2PR17|A0A1W2PR17_HUMAN,tr|Q5W015|Q5W015_HUMAN,tr|F2Z2I2|F2Z2I2_HUMAN,tr|H0Y483|H0Y483_HUMAN,tr|Q5VX20|Q5VX20_HUMAN" 6 1687.9067 3.06 49893 16161 3 1687.905848 563.6429 "6-phosphofructo-2-kinase\fructose-2,6-bisphosphatase 3 OS=Homo sapiens OX=9606 GN=PFKFB3 PE=1 SV=1" 6.74 2857.6 - 751831 - - - -0.5219 - 3.064 0.444 - 507 1 2 0 -0.0009 14 0 0 0 4.28E+07 1.40E+07 - - - 6.4656 0.9996 221125_WJC_METTL3_EV_vs_WT_F04.16162.16162.3 1.03E-07 Dec-64 K.LLVSQGASIYIENK[136.11]EEK[136.11].T "sp|O75832|PSD10_HUMAN,tr|B1AJY5|B1AJY5_HUMAN,tr|B1AJY7|B1AJY7_HUMAN" 3 1936.0488 1.43 49894 16162 3 1936.04311 646.3569 26S proteasome non-ATPase regulatory subunit 10 OS=Homo sapiens OX=9606 GN=PSMD10 PE=1 SV=1 4.79 2857.8 - 437829 - - - -2.9431 - 2.496 0.535 - 121.1 1 2 1 -0.0057 17 0 0 0 2.23E+07 1.56E+07 - - - 6.8139 1 221125_WJC_METTL3_EV_vs_WT_F04.16167.16167.3 3.68E-07 13/56 K.LLDPEDISVDHPDEK.S "sp|Q01082|SPTB2_HUMAN,tr|A0A087WUZ3|A0A087WUZ3_HUMAN,tr|F8W6C1|F8W6C1_HUMAN" 3 1720.8156 1.74 49897 16167 3 1720.813001 574.6125 "Spectrin beta chain, non-erythrocytic 1 OS=Homo sapiens OX=9606 GN=SPTBN1 PE=1 SV=2" 3.96 2858.4 - 2.00E+06 - - - -1.4871 - 2.507 0.544 - 183.2 1 2 0 -0.0026 15 0 0 0 3.29E+07 1.89E+07 - - - 7.0026 1 221125_WJC_METTL3_EV_vs_WT_F04.16168.16168.4 4.42E-06 13/198 R.SDSPVPTAPTSGGPK[136.11]PSTASAVPELATDPELEK[136.11]K[136.11].L "sp|Q86U44|MTA70_HUMAN,tr|B4E349|B4E349_HUMAN,tr|F5H6D8|F5H6D8_HUMAN,tr|B4DTN4|B4DTN4_HUMAN" 4 3384.7363 0.001 49898 16168 4 3384.73717 847.1913 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 4.51 2858.5 - 894093 - - - 0.2686 - 2.523 0.48 - 63.6 1 2 0 0.0009 34 0 0 0 0.00E+00 5.08E+06 - - - 3.6796 0.9964 221125_WJC_METTL3_EV_vs_WT_F04.16169.16169.2 0.00376 13/20 K.QQISLATQMVR.M "sp|P48643|TCPE_HUMAN,tr|E9PCA1|E9PCA1_HUMAN,tr|B7ZAR1|B7ZAR1_HUMAN,tr|E7ENZ3|E7ENZ3_HUMAN" 4 1273.6813 0.37 49899 16169 2 1273.685954 637.8479 T-complex protein 1 subunit epsilon OS=Homo sapiens OX=9606 GN=CCT5 PE=1 SV=1 9.75 2858.6 - 867600 - - - 3.6885 - 2.416 0.224 - 835.3 1 2 0 0.0047 11 0 0 0 6.79E+06 1.84E+07 - - - 3.0803 1 221125_WJC_METTL3_EV_vs_WT_F04.16170.16170.2 1.39E-09 15/24 R.YPGGESYQDLVQR.L sp|O60825|F262_HUMAN 1 1510.7052 7.29 49900 16170 2 1510.706012 756.3599 "6-phosphofructo-2-kinase\fructose-2,6-bisphosphatase 2 OS=Homo sapiens OX=9606 GN=PFKFB2 PE=1 SV=2" 4.37 2858.7 - 757761 - - - 0.5229 - 2.691 0.642 - 946.5 1 2 0 0.0008 13 0 0 0 6.75E+06 9.26E+05 - - - 6.3232 0.9999 221125_WJC_METTL3_EV_vs_WT_F04.16174.16174.3 4.04E-06 13/48 K.VFIQHITLSDEER.K "sp|Q14527|HLTF_HUMAN,tr|H7C5K0|H7C5K0_HUMAN,tr|A0A0C4DGA6|A0A0C4DGA6_HUMAN" 3 1585.81 1.07 49902 16174 3 1585.808728 529.6106 Helicase-like transcription factor OS=Homo sapiens OX=9606 GN=HLTF PE=1 SV=2 4.65 2859.3 - 2.64E+06 - - - -0.8154 - 2.535 0.431 - 212 1 2 0 -0.0013 13 0 0 0 2.99E+07 2.81E+07 - - - 5.8669 0.9161 221125_WJC_METTL3_EV_vs_WT_F04.16176.16176.3 0.139 14/48 K.GAAGR[166.11]PLELSDFR[166.11].M "sp|P42167|LAP2B_HUMAN,tr|G5E972|G5E972_HUMAN,tr|H0YJH7|H0YJH7_HUMAN" 3 1407.7374 1.08 49904 16176 3 1407.7303 470.2531 "Lamina-associated polypeptide 2, isoforms beta\gamma OS=Homo sapiens OX=9606 GN=TMPO PE=1 SV=2" 6.07 2859.5 - 1.57E+06 - - - -5.0095 - 2.304 0.122 - 220.9 1 2 0 -0.0071 13 0 0 0 9.59E+07 8.86E+07 - - - 2.1612 1 221125_WJC_METTL3_EV_vs_WT_F04.16178.16178.2 1.57E-09 19/30 R.EAGAGGLAIAVEGPSK.A "sp|P21333|FLNA_HUMAN,tr|A0A7P0NMY4|A0A7P0NMY4_HUMAN,tr|Q60FE5|Q60FE5_HUMAN,tr|H0Y5C6|H0Y5C6_HUMAN" 4 1425.7464 1.31 49906 16178 2 1425.750652 713.8805 Filamin-A OS=Homo sapiens OX=9606 GN=FLNA PE=1 SV=4 4.53 2859.7 - 1.07E+06 - - - 3.0118 - 3.547 0.626 - 1319.5 1 2 0 0.0043 16 0 0 0 2.04E+07 1.56E+07 - - - 6.7761 0.9986 221125_WJC_METTL3_EV_vs_WT_F04.16179.16179.2 0.000108 20-Nov K.GFKEQIYDVYR.Y "sp|P38919|IF4A3_HUMAN,tr|I3L3H2|I3L3H2_HUMAN" 2 1416.7038 6.76 49907 16179 2 1416.703897 709.3592 Eukaryotic initiation factor 4A-III OS=Homo sapiens OX=9606 GN=EIF4A3 PE=1 SV=4 6.07 2859.9 - 503275 - - - 0.0932 - 2.278 0.472 - 298.5 1 2 1 0.0001 11 0 0 0 8.43E+06 1.25E+06 - - - 4.7544 0.9865 221125_WJC_METTL3_EV_vs_WT_F04.16180.16180.2 0.00192 14/28 G.GGFSSGGFSGGSFSR.G "sp|P13645|K1C10_HUMAN,tr|A0A1B0GVI3|A0A1B0GVI3_HUMAN" 2 1392.6058 999 49908 16180 2 1392.607279 697.3102 "Keratin, type I cytoskeletal 10 OS=Homo sapiens OX=9606 GN=KRT10 PE=1 SV=6" 9.75 2860 - 417327 - - - 1.0319 - 2.772 0.375 - 399.2 1 1 0 0.0014 15 0 0 0 6.64E+06 0.00E+00 - - - 4.317 0.9998 221125_WJC_METTL3_EV_vs_WT_F04.16183.16183.3 0.0023 14/52 K.TLQEVTQLSQEAQR[166.11].L "sp|P40939|ECHA_HUMAN,tr|A0A2R8YG21|A0A2R8YG21_HUMAN,tr|A0A2R8Y688|A0A2R8Y688_HUMAN,tr|H0YFD6|H0YFD6_HUMAN,tr|A0A2R8Y4F5|A0A2R8Y4F5_HUMAN" 5 1639.8405 0.66 49909 16183 3 1639.83853 547.6208 "Trifunctional enzyme subunit alpha, mitochondrial OS=Homo sapiens OX=9606 GN=HADHA PE=1 SV=2" 4.53 2860.4 - 1.85E+06 - - - -1.191 - 2.352 0.361 - 237.2 1 2 0 -0.002 14 0 0 0 1.74E+07 2.63E+07 - - - 4.8372 0.9998 221125_WJC_METTL3_EV_vs_WT_F04.16184.16184.2 0.00032 18-Oct K.GNKPWISLPR.G "sp|P62701|RS4X_HUMAN,sp|P22090|RS4Y1_HUMAN,sp|Q8TD47|RS4Y2_HUMAN,tr|C9JEH7|C9JEH7_HUMAN" 4 1166.656 0.93 49910 16184 2 1166.656101 584.3353 "40S ribosomal protein S4, X isoform OS=Homo sapiens OX=9606 GN=RPS4X PE=1 SV=2" 11 2860.5 - 1.61E+06 - - - 0.0634 - 1.879 0.437 - 284.4 1 2 0 0.0001 10 0 0 0 4.72E+07 5.05E+07 - - - 4.0292 0.9999 221125_WJC_METTL3_EV_vs_WT_F04.16185.16185.3 6.39E-05 15/48 K.GAAGRPLELSDFR.M "sp|P42167|LAP2B_HUMAN,tr|G5E972|G5E972_HUMAN,tr|H0YJH7|H0YJH7_HUMAN" 3 1387.7208 1.08 49911 16185 3 1387.720213 463.5809 "Lamina-associated polypeptide 2, isoforms beta\gamma OS=Homo sapiens OX=9606 GN=TMPO PE=1 SV=2" 6.07 2860.6 - 1.80E+06 - - - -0.4316 - 2.426 0.442 - 251.7 1 2 0 -0.0006 13 0 0 0 9.59E+07 8.86E+07 - - - 5.8706 0.9999 221125_WJC_METTL3_EV_vs_WT_F04.16187.16187.2 2.59E-06 14/26 K.AEAGAGSATEFQFR[166.11].G "sp|Q9NQ39|RS10L_HUMAN,sp|P46783|RS10_HUMAN" 2 1450.6716 2.85 49913 16187 2 1450.670105 726.3431 Putative 40S ribosomal protein S10-like OS=Homo sapiens OX=9606 GN=RPS10P5 PE=5 SV=1 4.53 2860.8 - 1.02E+06 - - - -1.0492 - 2.973 0.532 - 737.3 1 2 0 -0.0015 14 0 0 0 3.83E+07 1.34E+07 - - - 5.7041 0.9998 221125_WJC_METTL3_EV_vs_WT_F04.16188.16188.2 0.0675 14/26 K.TLQEVTQLSQEAQR[166.11].L "sp|P40939|ECHA_HUMAN,tr|A0A2R8YG21|A0A2R8YG21_HUMAN,tr|A0A2R8Y688|A0A2R8Y688_HUMAN,tr|H0YFD6|H0YFD6_HUMAN,tr|A0A2R8Y4F5|A0A2R8Y4F5_HUMAN" 5 1639.8405 0.46 49914 16188 2 1639.837614 820.9275 "Trifunctional enzyme subunit alpha, mitochondrial OS=Homo sapiens OX=9606 GN=HADHA PE=1 SV=2" 4.53 2860.9 - 956228 - - - -1.7496 - 2.868 0.423 - 595.9 1 2 0 -0.0029 14 0 0 0 7.35E+06 1.58E+07 - - - 4.8084 1 221125_WJC_METTL3_EV_vs_WT_F04.16189.16189.2 6.24E-13 13/28 K.GYDFESETDTETIAK[136.11].L "sp|Q06210|GFPT1_HUMAN,tr|A0A6I8PRN4|A0A6I8PRN4_HUMAN,tr|A0A6I8PTT9|A0A6I8PTT9_HUMAN" 3 1712.7508 1.2 49915 16189 2 1712.750817 857.3827 Glutamine--fructose-6-phosphate aminotransferase [isomerizing] 1 OS=Homo sapiens OX=9606 GN=GFPT1 PE=1 SV=3 3.83 2861.1 - 486137 - - - -0.014 - 2.695 0.708 - 539.2 1 2 0 0 15 0 0 0 4.76E+07 3.98E+07 - - - 6.7077 0.9999 221125_WJC_METTL3_EV_vs_WT_F04.16190.16190.3 1.43E-06 13/40 R.HFEATDILVSK.L "sp|O60841|IF2P_HUMAN,tr|A0A087WUT6|A0A087WUT6_HUMAN" 2 1258.6558 0.76 49916 16190 3 1258.657968 420.5592 Eukaryotic translation initiation factor 5B OS=Homo sapiens OX=9606 GN=EIF5B PE=1 SV=4 5.32 2861.2 - 466576 - - - 1.7606 - 2.171 0.493 - 177.9 1 2 0 0.0022 11 0 0 0 7.51E+06 9.89E+06 - - - 6.238 0.9997 221125_WJC_METTL3_EV_vs_WT_F04.16191.16191.2 0.00162 Dec-36 R.LGAAALVPEAQDSQVTSTK.S "sp|Q8N9M1|CS047_HUMAN,tr|A0A2R8Y6U9|A0A2R8Y6U9_HUMAN,tr|A0A804HLH2|A0A804HLH2_HUMAN" 3 1884.9793 1.42 49917 16191 2 1884.976367 943.4969 Uncharacterized protein C19orf47 OS=Homo sapiens OX=9606 GN=C19orf47 PE=1 SV=1 4.37 2861.3 - 406567 - - - -1.5411 - 2.313 0.433 - 213.9 1 2 0 -0.0029 19 0 0 0 7.41E+06 5.23E+06 - - - 4.2998 0.9997 221125_WJC_METTL3_EV_vs_WT_F04.16192.16192.2 5.56E-05 26-Nov K.LVEQLDIEETEQSK.L "sp|Q92552|RT27_HUMAN,tr|G5EA06|G5EA06_HUMAN,tr|D6RH20|D6RH20_HUMAN" 3 1659.8203 1.27 49918 16192 2 1659.818047 830.9174 "28S ribosomal protein S27, mitochondrial OS=Homo sapiens OX=9606 GN=MRPS27 PE=1 SV=3" 3.91 2861.5 - 385412 - - - -1.364 - 1.795 0.465 - 314.9 1 2 0 -0.0023 14 0 0 0 5.93E+06 4.69E+06 - - - 3.9428 0.9954 221125_WJC_METTL3_EV_vs_WT_F04.16198.16198.3 0.000151 14/52 S.ADAPMFVMGVNHEK.Y "sp|P04406|G3P_HUMAN,tr|E7EUT5|E7EUT5_HUMAN" 2 1544.7116 0.53 49922 16198 3 1544.712473 515.9111 Glyceraldehyde-3-phosphate dehydrogenase OS=Homo sapiens OX=9606 GN=GAPDH PE=1 SV=3 5.32 2862.2 - 1.07E+06 - - - 0.5846 - 2.322 0.472 - 256.4 1 1 0 0.0009 14 0 0 0 1.60E+07 2.99E+07 - - - 6.0409 0.9998 221125_WJC_METTL3_EV_vs_WT_F04.16199.16199.3 1.08E-05 17/64 K.LLVSQGASIYIENKEEK.T "sp|O75832|PSD10_HUMAN,tr|B1AJY5|B1AJY5_HUMAN,tr|B1AJY7|B1AJY7_HUMAN" 3 1920.0204 1.41 49923 16199 3 1920.0199 641.0141 26S proteasome non-ATPase regulatory subunit 10 OS=Homo sapiens OX=9606 GN=PSMD10 PE=1 SV=1 4.79 2862.3 - 1.47E+06 - - - -0.2646 - 2.751 0.452 - 253.3 1 2 1 -0.0005 17 0 0 0 2.30E+07 1.64E+07 - - - 6.1357 0.9995 221125_WJC_METTL3_EV_vs_WT_F04.16200.16200.3 3.78E-06 17/48 R.QR[166.11]YEILTPNAIPK[136.11].G "sp|Q7Z406|MYH14_HUMAN,sp|P35580|MYH10_HUMAN,tr|M0QY43|M0QY43_HUMAN" 3 1559.879 0.9 49924 16200 3 1559.879291 520.967 Myosin-14 OS=Homo sapiens OX=9606 GN=MYH14 PE=1 SV=2 8.59 2862.4 - 1.11E+06 - - - 0.1558 - 2.511 0.366 - 508.3 1 2 1 0.0002 13 0 0 0 1.67E+07 1.86E+07 - - - 5.1167 1 221125_WJC_METTL3_EV_vs_WT_F04.16201.16201.2 7.74E-09 16/28 K.GYDFESETDTETIAK.L "sp|Q06210|GFPT1_HUMAN,tr|A0A6I8PRN4|A0A6I8PRN4_HUMAN,tr|A0A6I8PTT9|A0A6I8PTT9_HUMAN" 3 1704.7366 1.2 49925 16201 2 1704.736968 853.3756 Glutamine--fructose-6-phosphate aminotransferase [isomerizing] 1 OS=Homo sapiens OX=9606 GN=GFPT1 PE=1 SV=3 3.83 2862.5 - 968678 - - - 0.1918 - 3.184 0.68 - 852.3 1 2 0 0.0003 15 0 0 0 4.77E+07 3.99E+07 - - - 6.9107 0.9999 221125_WJC_METTL3_EV_vs_WT_F04.16205.16205.2 3.98E-05 14/36 R.LGAAALVPEAQDSQVTSTK[136.11].S "sp|Q8N9M1|CS047_HUMAN,tr|A0A2R8Y6U9|A0A2R8Y6U9_HUMAN,tr|A0A804HLH2|A0A804HLH2_HUMAN" 3 1892.9935 1.42 49929 16205 2 1892.994632 947.504 Uncharacterized protein C19orf47 OS=Homo sapiens OX=9606 GN=C19orf47 PE=1 SV=1 4.37 2863 - 376118 - - - 0.6128 - 2.687 0.469 - 342.6 1 2 0 0.0012 19 0 0 0 7.41E+06 5.23E+06 - - - 4.9348 0.9303 221125_WJC_METTL3_EV_vs_WT_F04.16206.16206.2 0.0153 Jun-36 A.GGAIPGQAPGSVPGPGLVK.D "tr|A0A804CDA6|A0A804CDA6_HUMAN,tr|E7EX90|E7EX90_HUMAN" 2 1657.9152 5.96 49930 16206 2 1657.916965 829.9649 Dynactin subunit 1 OS=Homo sapiens OX=9606 GN=DCTN1 PE=4 SV=1 8.75 2863.2 - 285696 - - - 1.0917 - 1.431 0.344 - 67.2 1 1 0 0.0018 19 0 0 0 5.40E+06 9.07E+05 - - - 2.4623 1 221125_WJC_METTL3_EV_vs_WT_F04.16209.16209.3 5.66E-05 16/72 K.NLPPSGAVPVTGIPPHVVK.V "sp|Q13283|G3BP1_HUMAN,tr|A0A7I2V5M7|A0A7I2V5M7_HUMAN,tr|A0A7I2YQM1|A0A7I2YQM1_HUMAN,tr|A0A7P0P2U7|A0A7P0P2U7_HUMAN,tr|A0A7I2YQU8|A0A7I2YQU8_HUMAN,tr|A0A7I2V548|A0A7I2V548_HUMAN,tr|A0A7I2V651|A0A7I2V651_HUMAN,tr|A0A7I2V4D8|A0A7I2V4D8_HUMAN,tr|A0A7I2YQN9|A0A7I2YQN9_HUMAN" 9 1878.0727 1.36 49932 16209 3 1878.073279 627.0315 Ras GTPase-activating protein-binding protein 1 OS=Homo sapiens OX=9606 GN=G3BP1 PE=1 SV=1 8.76 2863.5 - 2.62E+06 - - - 0.2987 - 2.405 0.504 - 225.1 1 2 0 0.0006 19 0 0 0 5.93E+07 4.36E+07 - - - 6.3149 0.9999 221125_WJC_METTL3_EV_vs_WT_F04.16211.16211.2 2.00E-07 24-Nov R.AGVNTVTTLVENK[136.11].K "sp|P62424|RL7A_HUMAN,tr|Q5T8U2|Q5T8U2_HUMAN,tr|Q5T8U3|Q5T8U3_HUMAN" 3 1352.7391 0.79 49933 16211 2 1352.738707 677.3768 60S ribosomal protein L7a OS=Homo sapiens OX=9606 GN=RPL7A PE=1 SV=2 6.05 2863.7 - 2.55E+06 - - - -0.2868 - 2.441 0.538 - 409.5 1 2 0 -0.0004 13 0 0 0 1.84E+07 2.33E+07 - - - 5.3049 0.9994 221125_WJC_METTL3_EV_vs_WT_F04.16212.16212.3 0.000451 Dec-48 R.QRYEILTPNAIPK.G "sp|Q7Z406|MYH14_HUMAN,sp|P35580|MYH10_HUMAN,tr|M0QY43|M0QY43_HUMAN" 3 1541.8566 0.9 49934 16212 3 1541.856864 514.9595 Myosin-14 OS=Homo sapiens OX=9606 GN=MYH14 PE=1 SV=2 8.59 2863.8 - 995167 - - - 0.1855 - 2.189 0.387 - 249.9 1 2 1 0.0003 13 0 0 0 1.67E+07 1.86E+07 - - - 4.9787 1 221125_WJC_METTL3_EV_vs_WT_F04.16213.16213.2 3.73E-09 20/30 R.EAGAGGLAIAVEGPSK[136.11].A "sp|P21333|FLNA_HUMAN,tr|A0A7P0NMY4|A0A7P0NMY4_HUMAN,tr|Q60FE5|Q60FE5_HUMAN,tr|H0Y5C6|H0Y5C6_HUMAN" 4 1433.7606 1.31 49935 16213 2 1433.762792 717.8876 Filamin-A OS=Homo sapiens OX=9606 GN=FLNA PE=1 SV=4 4.53 2863.9 - 943761 - - - 1.5581 - 3.338 0.609 - 1453.7 1 2 0 0.0022 16 0 0 0 2.04E+07 1.56E+07 - - - 6.5018 1 221125_WJC_METTL3_EV_vs_WT_F04.16214.16214.2 1.34E-06 14/30 K.SITILSTPEGTSAAC[160.03]K.S sp|O00425|IF2B3_HUMAN 1 1634.8185 1.75 49936 16214 2 1634.819039 818.4165 Insulin-like growth factor 2 mRNA-binding protein 3 OS=Homo sapiens OX=9606 GN=IGF2BP3 PE=1 SV=2 5.72 2864.1 - 889672 - - - 0.3071 - 3.055 0.606 - 580.9 1 2 0 0.0005 16 0 0 0 1.29E+07 7.37E+06 - - - 6.2624 0.9807 221125_WJC_METTL3_EV_vs_WT_F04.16216.16216.3 0.261 Nov-52 K.VIASELGSMPELK[136.11]K[136.11].Y "sp|Q9P2J5|SYLC_HUMAN,tr|A0A6I8PIV1|A0A6I8PIV1_HUMAN,tr|A0A6I8PRS0|A0A6I8PRS0_HUMAN,tr|A0A6I8PLB8|A0A6I8PLB8_HUMAN,tr|A0A6I8PIT3|A0A6I8PIT3_HUMAN,tr|A0A6I8PLB3|A0A6I8PLB3_HUMAN,tr|A0A6I8PS05|A0A6I8PS05_HUMAN,tr|B4DER1|B4DER1_HUMAN,tr|A0A6I8PL42|A0A6I8PL42_HUMAN" 9 1516.8506 0.37 49938 16216 3 1516.84896 506.6241 "Leucine--tRNA ligase, cytoplasmic OS=Homo sapiens OX=9606 GN=LARS1 PE=1 SV=2" 6.11 2864.3 - 722685 - - - -1.0588 - 1.69 0.134 - 86.3 1 2 0 -0.0016 14 0 0 0 3.70E+06 9.92E+06 - - - 1.428 1 221125_WJC_METTL3_EV_vs_WT_F04.16218.16218.3 9.77E-06 14/76 R.QVEPLDPPAGSAPGEHVFVK.G "sp|P54577|SYYC_HUMAN,tr|A0A6Q8PFX2|A0A6Q8PFX2_HUMAN" 2 2073.0531 0.82 49940 16218 3 2073.054081 692.025 "Tyrosine--tRNA ligase, cytoplasmic OS=Homo sapiens OX=9606 GN=YARS1 PE=1 SV=4" 4.65 2864.5 - 665696 - - - 0.4708 - 2.871 0.452 - 166.1 1 2 0 0.001 20 0 0 0 1.70E+07 2.08E+07 - - - 6.1377 0.9999 221125_WJC_METTL3_EV_vs_WT_F04.16220.16220.3 0.000291 15/56 K.IFGDHPIPQYEVNPR[166.11].T "sp|Q96CS2|HAUS1_HUMAN,tr|K7EK72|K7EK72_HUMAN,tr|K7EM54|K7EM54_HUMAN,tr|K7EJA9|K7EJA9_HUMAN,tr|K7EKH4|K7EKH4_HUMAN,tr|K7EQT8|K7EQT8_HUMAN" 6 1790.8979 1.63 49942 16220 3 1790.897461 597.9733 HAUS augmin-like complex subunit 1 OS=Homo sapiens OX=9606 GN=HAUS1 PE=1 SV=1 5.32 2864.8 - 529569 - - - -0.2669 - 2.325 0.37 - 189.3 1 2 0 -0.0005 15 0 0 0 1.05E+07 6.40E+06 - - - 4.8666 0.9998 221125_WJC_METTL3_EV_vs_WT_F04.16223.16223.2 1.88E-06 22-Oct K.NNPVMSLQDQVR.F "sp|Q7LGA3|HS2ST_HUMAN,tr|K7EP71|K7EP71_HUMAN" 2 1399.6878 1.39 49945 16223 2 1399.690046 700.8512 Heparan sulfate 2-O-sulfotransferase 1 OS=Homo sapiens OX=9606 GN=HS2ST1 PE=1 SV=1 5.84 2865.1 - 330275 - - - 1.6061 - 2.193 0.564 - 375.6 1 2 0 0.0022 12 0 0 0 7.16E+06 5.15E+06 - - - 5.2722 0.9998 221125_WJC_METTL3_EV_vs_WT_F04.16224.16224.3 0.0234 14/36 R.R[166.11]EPLSLINVR[166.11].K sp|Q96HS1|PGAM5_HUMAN 1 1215.7202 1.27 49946 16224 3 1215.716938 406.2474 "Serine\threonine-protein phosphatase PGAM5, mitochondrial OS=Homo sapiens OX=9606 GN=PGAM5 PE=1 SV=2" 9.6 2865.3 - 314103 - - - -2.721 - 2.634 0.4 - 291.6 1 2 0 -0.0033 10 0 0 0 4.77E+06 3.76E+06 - - - 5.8271 0.9999 221125_WJC_METTL3_EV_vs_WT_F04.16226.16226.3 3.25E-05 13/36 K.GNKPWISLPR.G "sp|P62701|RS4X_HUMAN,sp|P22090|RS4Y1_HUMAN,sp|Q8TD47|RS4Y2_HUMAN,tr|C9JEH7|C9JEH7_HUMAN" 4 1166.656 0.94 49947 16226 3 1166.655349 389.8926 "40S ribosomal protein S4, X isoform OS=Homo sapiens OX=9606 GN=RPS4X PE=1 SV=2" 11 2865.5 - 3.59E+07 - - - -0.5811 - 2.474 0.387 - 272.3 1 2 0 -0.0007 10 0 0 0 4.00E+08 4.27E+08 - - - 5.4999 0.9997 221125_WJC_METTL3_EV_vs_WT_F04.16229.16229.2 4.68E-05 22-Oct K.QLSSEELEQFQK[136.11].T "sp|P41252|SYIC_HUMAN,tr|A0A804HL54|A0A804HL54_HUMAN,tr|A0A804HIV9|A0A804HIV9_HUMAN,tr|A0A804HJN6|A0A804HJN6_HUMAN,tr|A0A804HHW9|A0A804HHW9_HUMAN,tr|A0A0A0MSX9|A0A0A0MSX9_HUMAN,tr|J3KR24|J3KR24_HUMAN,tr|A0A804HJ36|A0A804HJ36_HUMAN" 8 1472.7238 0.93 49949 16229 2 1472.724409 737.3692 "Isoleucine--tRNA ligase, cytoplasmic OS=Homo sapiens OX=9606 GN=IARS1 PE=1 SV=2" 4.25 2865.8 - 2.53E+06 - - - 0.387 - 2.251 0.322 - 333.7 1 2 0 0.0006 12 0 0 0 3.15E+07 3.40E+07 - - - 3.554 0.9998 221125_WJC_METTL3_EV_vs_WT_F04.16230.16230.3 0.000645 14/40 R.NLDVQLLDTK[136.11]R[166.11].Q sp|P12270|TPR_HUMAN 1 1331.7528 10.69 49950 16230 3 1331.751881 444.9249 Nucleoprotein TPR OS=Homo sapiens OX=9606 GN=TPR PE=1 SV=3 5.96 2865.9 - 1.15E+06 - - - -0.6781 - 2.123 0.357 - 321.9 1 2 0 -0.0009 11 0 0 0 1.06E+08 9.88E+06 - - - 4.6586 1 221125_WJC_METTL3_EV_vs_WT_F04.16231.16231.3 1.43E-07 19/52 K.LVRPPVQVYGIEGR.Y "sp|P48047|ATPO_HUMAN,tr|H7C086|H7C086_HUMAN,tr|H7C0C1|H7C0C1_HUMAN,tr|A0A494C0K9|A0A494C0K9_HUMAN" 4 1581.8991 1.25 49951 16231 3 1581.902341 528.307 "ATP synthase subunit O, mitochondrial OS=Homo sapiens OX=9606 GN=ATP5PO PE=1 SV=1" 8.75 2866 - 928603 - - - 2.0418 - 3.571 0.621 - 599 1 2 0 0.0032 14 0 0 0 1.49E+07 1.19E+07 - - - 8.8453 1 221125_WJC_METTL3_EV_vs_WT_F04.16232.16232.3 5.56E-10 20/56 R.VILAGNLLSHSTQSR.D "sp|P49005|DPOD2_HUMAN,tr|A0A087WWF6|A0A087WWF6_HUMAN,tr|F8W8R3|F8W8R3_HUMAN,tr|C9JHC7|C9JHC7_HUMAN" 4 1594.8791 1.31 49952 16232 3 1594.879613 532.6336 DNA polymerase delta subunit 2 OS=Homo sapiens OX=9606 GN=POLD2 PE=1 SV=1 9.73 2866.1 - 693098 - - - 0.3191 - 3.404 0.472 - 467.4 1 2 0 0.0005 15 0 0 0 8.13E+06 6.23E+06 - - - 6.9985 1 221125_WJC_METTL3_EV_vs_WT_F04.16233.16233.3 3.37E-07 17/60 K.LPAEPPALLQTHPPC[160.03]R.R "sp|Q92667|AKAP1_HUMAN,tr|I3L2A2|I3L2A2_HUMAN,tr|I3L0K6|I3L0K6_HUMAN,tr|I3L2N7|I3L2N7_HUMAN" 4 1795.9403 1.91 49953 16233 3 1795.940117 599.6541 "A-kinase anchor protein 1, mitochondrial OS=Homo sapiens OX=9606 GN=AKAP1 PE=1 SV=1" 6.74 2866.3 - 682460 - - - -0.1153 - 2.919 0.506 - 273.5 1 2 0 -0.0002 16 0 0 0 8.07E+06 4.23E+06 - - - 6.93 1 221125_WJC_METTL3_EV_vs_WT_F04.16234.16234.2 4.90E-13 16/30 R.NSTEC[160.03]TLILTEGDSAK[136.11].T sp|P11388|TOP2A_HUMAN 1 1745.8233 1.26 49954 16234 2 1745.821872 873.9189 DNA topoisomerase 2-alpha OS=Homo sapiens OX=9606 GN=TOP2A PE=1 SV=3 4.14 2866.4 - 541222 - - - -0.8151 - 3.201 0.737 - 958.8 1 2 0 -0.0014 16 0 0 0 6.13E+06 4.85E+06 - - - 7.3445 1 221125_WJC_METTL3_EV_vs_WT_F04.16235.16235.3 1.01E-07 21/60 K.LPAEPPALLQTHPPC[160.03]R[166.11].R "sp|Q92667|AKAP1_HUMAN,tr|I3L2A2|I3L2A2_HUMAN,tr|I3L0K6|I3L0K6_HUMAN,tr|I3L2N7|I3L2N7_HUMAN" 4 1805.9486 1.82 49955 16235 3 1805.953045 602.9901 "A-kinase anchor protein 1, mitochondrial OS=Homo sapiens OX=9606 GN=AKAP1 PE=1 SV=1" 6.74 2866.5 - 423420 - - - 2.4646 - 3.509 0.598 - 544.9 1 2 0 0.0045 16 0 0 0 7.72E+06 4.23E+06 - - - 8.4269 0.9998 221125_WJC_METTL3_EV_vs_WT_F04.16237.16237.3 0.000559 Aug-36 R.VESHFDLELR.A "sp|Q6P2Q9|PRP8_HUMAN,tr|I3L0J9|I3L0J9_HUMAN" 2 1243.6197 0.8 49957 16237 3 1243.620843 415.5472 Pre-mRNA-processing-splicing factor 8 OS=Homo sapiens OX=9606 GN=PRPF8 PE=1 SV=2 4.65 2866.8 - 294010 - - - 0.9183 - 1.805 0.402 - 111.1 1 2 0 0.0011 10 0 0 0 2.57E+06 3.20E+06 - - - 4.7463 0.9995 221125_WJC_METTL3_EV_vs_WT_F04.16244.16244.2 0.52 18-Nov R.NLVDNITGQR.L "sp|Q15149|PLEC_HUMAN,tr|H0YDN1|H0YDN1_HUMAN" 2 1128.5887 2.16 49963 16244 2 1128.589085 565.3016 Plectin OS=Homo sapiens OX=9606 GN=PLEC PE=1 SV=3 5.84 2867.6 - 1.48E+06 - - - 0.3092 - 2.002 0.278 - 431 1 2 0 0.0003 10 0 0 0 1.58E+07 7.32E+06 - - - 3.0318 0.9996 221125_WJC_METTL3_EV_vs_WT_F04.16245.16245.2 0.0155 16-Oct R.EQVNDLFSR.K "sp|P78347|GTF2I_HUMAN,sp|Q86UP8|GTD2A_HUMAN,sp|Q6EKJ0|GTD2B_HUMAN,tr|A0A494C1N8|A0A494C1N8_HUMAN,tr|A0A087WW90|A0A087WW90_HUMAN,tr|A0A0D9SF80|A0A0D9SF80_HUMAN,tr|A0A494C0I1|A0A494C0I1_HUMAN,tr|A0A494C1K3|A0A494C1K3_HUMAN" 8 1106.5356 1.34 49964 16245 2 1106.536357 554.2751 General transcription factor II-I OS=Homo sapiens OX=9606 GN=GTF2I PE=1 SV=2 4.37 2867.7 - 1.28E+06 - - - 0.6507 - 1.906 0.351 - 489.3 1 2 0 0.0007 9 0 0 0 3.10E+07 2.32E+07 - - - 3.4993 1 221125_WJC_METTL3_EV_vs_WT_F04.16246.16246.3 9.08E-08 13/48 R.K[136.11]VVVVVPNEEDWK[136.11].K "sp|Q1KMD3|HNRL2_HUMAN,tr|H3BQZ7|H3BQZ7_HUMAN" 2 1555.8581 1.05 49965 16246 3 1555.858508 519.6266 Heterogeneous nuclear ribonucleoprotein U-like protein 2 OS=Homo sapiens OX=9606 GN=HNRNPUL2 PE=1 SV=1 4.68 2867.8 - 1.07E+06 - - - 0.2661 - 2.465 0.544 - 260.5 1 2 0 0.0004 13 0 0 0 1.01E+07 9.61E+06 - - - 7.0511 1 221125_WJC_METTL3_EV_vs_WT_F04.16247.16247.3 0.000456 16/48 R.VAELSSDDFHLDR.H "sp|Q92896|GSLG1_HUMAN,tr|H3BM42|H3BM42_HUMAN" 2 1502.7001 1.3 49966 16247 3 1502.70126 501.9073 Golgi apparatus protein 1 OS=Homo sapiens OX=9606 GN=GLG1 PE=1 SV=2 4.22 2867.9 - 884202 - - - 0.7473 - 3.713 0.525 - 553.5 1 2 0 0.0011 13 0 0 0 1.49E+07 1.15E+07 - - - 7.9497 0.9999 221125_WJC_METTL3_EV_vs_WT_F04.16248.16248.3 4.79E-06 Nov-40 R.FC[160.03]LGQLSNVHR[166.11].T "sp|Q13485|SMAD4_HUMAN,tr|K7EIU8|K7EIU8_HUMAN,tr|A0A087WUF3|A0A087WUF3_HUMAN" 3 1339.6695 0.79 49967 16248 3 1339.668882 447.5638 Mothers against decapentaplegic homolog 4 OS=Homo sapiens OX=9606 GN=SMAD4 PE=1 SV=1 8.26 2868 - 632340 - - - -0.4307 - 2.074 0.473 - 130.1 1 2 0 -0.0006 11 0 0 0 4.39E+06 5.58E+06 - - - 5.8856 1 221125_WJC_METTL3_EV_vs_WT_F04.16250.16250.2 2.55E-12 17/32 R.YDAFGEDSSSAMGVENR.A sp|Q9Y2X3|NOP58_HUMAN 1 1833.7476 1.1 49969 16250 2 1833.745304 917.8811 Nucleolar protein 58 OS=Homo sapiens OX=9606 GN=NOP58 PE=1 SV=1 3.92 2868.2 - 424731 - - - -1.2286 - 3.337 0.81 - 1042.7 1 2 0 -0.0023 17 0 0 0 2.89E+06 2.64E+06 - - - 7.9857 0.9996 221125_WJC_METTL3_EV_vs_WT_F04.16251.16251.3 0.000201 Nov-56 K.GYDFESETDTETIAK[136.11].L "sp|Q06210|GFPT1_HUMAN,tr|A0A6I8PRN4|A0A6I8PRN4_HUMAN,tr|A0A6I8PTT9|A0A6I8PTT9_HUMAN" 3 1712.7508 0.93 49970 16251 3 1712.75357 571.9242 Glutamine--fructose-6-phosphate aminotransferase [isomerizing] 1 OS=Homo sapiens OX=9606 GN=GFPT1 PE=1 SV=3 3.83 2868.3 - 393538 - - - 1.5933 - 1.935 0.361 - 103 1 2 0 0.0027 15 0 0 0 2.89E+06 3.11E+06 - - - 4.2865 0.9992 221125_WJC_METTL3_EV_vs_WT_F04.16252.16252.3 0.132 Aug-36 R.VESHFDLELR[166.11].A "sp|Q6P2Q9|PRP8_HUMAN,tr|I3L0J9|I3L0J9_HUMAN" 2 1253.628 0.8 49971 16252 3 1253.627407 418.8833 Pre-mRNA-processing-splicing factor 8 OS=Homo sapiens OX=9606 GN=PRPF8 PE=1 SV=2 4.65 2868.5 - 393397 - - - -0.4499 - 1.602 0.317 - 114.5 1 2 0 -0.0006 10 0 0 0 2.53E+06 3.17E+06 - - - 3.4503 0.9998 221125_WJC_METTL3_EV_vs_WT_F04.16253.16253.3 0.000562 Dec-56 R.FQVAVNLAEDTAHPK[136.11].L sp|Q9C037|TRIM4_HUMAN 1 1646.8508 11.27 49972 16253 3 1646.852872 549.9575 E3 ubiquitin-protein ligase TRIM4 OS=Homo sapiens OX=9606 GN=TRIM4 PE=1 SV=2 5.32 2868.6 - 270405 - - - 1.2764 - 1.96 0.405 - 136.4 1 2 0 0.0021 15 0 0 0 1.52E+07 1.35E+06 - - - 4.8107 0.9776 221125_WJC_METTL3_EV_vs_WT_F04.16257.16257.3 0.0465 Sep-36 K.EGEIIHLISK.E sp|Q9Y5K6|CD2AP_HUMAN 1 1137.6394 1.16 49976 16257 3 1137.644026 380.2204 CD2-associated protein OS=Homo sapiens OX=9606 GN=CD2AP PE=1 SV=1 5.4 2869.1 - 208722 - - - 4.0892 - 1.691 0.23 - 89.8 1 2 0 0.0047 10 0 0 0 1.74E+06 1.50E+06 - - - 2.6371 1 221125_WJC_METTL3_EV_vs_WT_F04.16258.16258.2 1.21E-06 26-Nov K.TPVTQVNEVTGTLR[166.11].L "sp|Q13405|RM49_HUMAN,tr|H0YDP7|H0YDP7_HUMAN" 2 1523.8183 3.17 49977 16258 2 1523.823908 762.9164 "39S ribosomal protein L49, mitochondrial OS=Homo sapiens OX=9606 GN=MRPL49 PE=1 SV=1" 5.66 2869.3 - 192304 - - - 3.6861 - 2.633 0.614 - 385.4 1 2 0 0.0056 14 0 0 0 5.25E+06 1.65E+06 - - - 6.0037 0.9999 221125_WJC_METTL3_EV_vs_WT_F04.16261.16261.2 1.11E-05 22-Nov K.QLSSEELEQFQK.T "sp|P41252|SYIC_HUMAN,tr|A0A804HL54|A0A804HL54_HUMAN,tr|A0A804HIV9|A0A804HIV9_HUMAN,tr|A0A804HJN6|A0A804HJN6_HUMAN,tr|A0A804HHW9|A0A804HHW9_HUMAN,tr|A0A0A0MSX9|A0A0A0MSX9_HUMAN,tr|J3KR24|J3KR24_HUMAN,tr|A0A804HJ36|A0A804HJ36_HUMAN" 8 1464.7096 0.93 49978 16261 2 1464.710075 733.3621 "Isoleucine--tRNA ligase, cytoplasmic OS=Homo sapiens OX=9606 GN=IARS1 PE=1 SV=2" 4.25 2869.7 - 3.74E+06 - - - 0.2977 - 2.432 0.479 - 423.7 1 2 0 0.0004 12 0 0 0 3.15E+07 3.40E+07 - - - 4.9171 1 221125_WJC_METTL3_EV_vs_WT_F04.16263.16263.3 4.18E-09 21/52 K.LVR[166.11]PPVQVYGIEGR[166.11].Y "sp|P48047|ATPO_HUMAN,tr|H7C086|H7C086_HUMAN,tr|H7C0C1|H7C0C1_HUMAN,tr|A0A494C0K9|A0A494C0K9_HUMAN" 4 1601.9157 1.25 49980 16263 3 1601.919335 534.9792 "ATP synthase subunit O, mitochondrial OS=Homo sapiens OX=9606 GN=ATP5PO PE=1 SV=1" 8.75 2869.8 - 1.10E+06 - - - 2.2997 - 3.392 0.582 - 812.5 1 2 0 0.0037 14 0 0 0 1.49E+07 1.19E+07 - - - 8.2737 0.9999 221125_WJC_METTL3_EV_vs_WT_F04.16264.16264.2 3.70E-07 15/24 R.TYNASITLQQQLK[136.11].E "sp|P11387|TOP1_HUMAN,tr|A0A7P0T852|A0A7P0T852_HUMAN" 2 1514.8184 0.61 49981 16264 2 1514.818887 758.4165 DNA topoisomerase 1 OS=Homo sapiens OX=9606 GN=TOP1 PE=1 SV=2 8.26 2870 - 907929 - - - 0.3162 - 2.943 0.376 - 650.4 1 2 0 0.0005 13 0 0 0 4.09E+06 6.75E+06 - - - 4.5884 0.9997 221125_WJC_METTL3_EV_vs_WT_F04.16267.16267.3 0.0142 Dec-40 R.FC[160.03]LGQLSNVHR.T "sp|Q13485|SMAD4_HUMAN,tr|K7EIU8|K7EIU8_HUMAN,tr|A0A087WUF3|A0A087WUF3_HUMAN" 3 1329.6612 0.77 49984 16267 3 1329.662607 444.2277 Mothers against decapentaplegic homolog 4 OS=Homo sapiens OX=9606 GN=SMAD4 PE=1 SV=1 8.26 2870.3 - 747475 - - - 1.0664 - 1.92 0.347 - 156.4 1 2 0 0.0014 11 0 0 0 4.41E+06 5.69E+06 - - - 4.2615 1 221125_WJC_METTL3_EV_vs_WT_F04.16268.16268.2 1.86E-06 24-Dec R.TYNASITLQQQLK.E "sp|P11387|TOP1_HUMAN,tr|A0A7P0T852|A0A7P0T852_HUMAN" 2 1506.8042 0.61 49985 16268 2 1506.804782 754.4094 DNA topoisomerase 1 OS=Homo sapiens OX=9606 GN=TOP1 PE=1 SV=2 8.26 2870.4 - 546947 - - - 0.3809 - 2.599 0.632 - 371.9 1 2 0 0.0006 13 0 0 0 4.09E+06 6.75E+06 - - - 6.1601 1 221125_WJC_METTL3_EV_vs_WT_F04.16271.16271.2 1.28E-14 16/32 R.YDAFGEDSSSAMGVENR[166.11].A sp|Q9Y2X3|NOP58_HUMAN 1 1843.7558 1.1 49988 16271 2 1843.754024 922.8852 Nucleolar protein 58 OS=Homo sapiens OX=9606 GN=NOP58 PE=1 SV=1 3.92 2870.8 - 448975 - - - -0.9779 - 3.246 0.788 - 899.2 1 2 0 -0.0018 17 0 0 0 2.89E+06 2.64E+06 - - - 7.7554 0.9999 221125_WJC_METTL3_EV_vs_WT_F04.16273.16273.3 4.66E-06 14/44 K.DSLDPSFTHALR.L sp|O75525|KHDR3_HUMAN 1 1357.6626 0.49 49990 16273 3 1357.664558 453.5615 "KH domain-containing, RNA-binding, signal transduction-associated protein 3 OS=Homo sapiens OX=9606 GN=KHDRBS3 PE=1 SV=1" 5.21 2871.1 - 323690 - - - 1.4208 - 2.668 0.446 - 295.4 1 2 0 0.0019 12 0 0 0 2.55E+06 5.25E+06 - - - 6.232 0.7686 221125_WJC_METTL3_EV_vs_WT_F04.16274.16274.3 1.4 Nov-72 R.LGAAALVPEAQDSQVTSTK[136.11].S "sp|Q8N9M1|CS047_HUMAN,tr|A0A2R8Y6U9|A0A2R8Y6U9_HUMAN,tr|A0A804HLH2|A0A804HLH2_HUMAN" 3 1892.9935 2.84 49991 16274 3 1892.995458 632.0051 Uncharacterized protein C19orf47 OS=Homo sapiens OX=9606 GN=C19orf47 PE=1 SV=1 4.37 2871.2 - 553018 - - - 1.0491 - 1.393 0.056 - 77.7 1 2 0 0.002 19 0 0 0 2.13E+07 7.47E+06 - - - -0.0219 0.9998 221125_WJC_METTL3_EV_vs_WT_F04.16279.16279.3 7.26E-05 Dec-60 R.VFDK[136.11]DGNGYISAAELR[166.11].H "sp|P0DP25|CALM3_HUMAN,sp|P0DP23|CALM1_HUMAN,sp|P0DP24|CALM2_HUMAN,tr|G3V361|G3V361_HUMAN,tr|A0A590UJI2|A0A590UJI2_HUMAN,tr|Q96HY3|Q96HY3_HUMAN,tr|E7EMB3|E7EMB3_HUMAN" 7 1771.886 1.17 49995 16279 3 1771.887791 591.6359 Calmodulin-3 OS=Homo sapiens OX=9606 GN=CALM3 PE=1 SV=1 4.56 2871.9 - 3.66E+06 - - - 1.0198 - 2.404 0.49 - 139.1 1 2 1 0.0018 16 0 0 0 8.78E+07 7.49E+07 - - - 6.2531 0.9998 221125_WJC_METTL3_EV_vs_WT_F04.16280.16280.3 9.30E-06 13/60 R.VFDKDGNGYISAAELR.H "sp|P0DP25|CALM3_HUMAN,sp|P0DP23|CALM1_HUMAN,sp|P0DP24|CALM2_HUMAN,tr|G3V361|G3V361_HUMAN,tr|A0A590UJI2|A0A590UJI2_HUMAN,tr|Q96HY3|Q96HY3_HUMAN,tr|E7EMB3|E7EMB3_HUMAN" 7 1753.8635 1.17 49996 16280 3 1753.866551 585.6284 Calmodulin-3 OS=Homo sapiens OX=9606 GN=CALM3 PE=1 SV=1 4.56 2871.9 - 3.38E+06 - - - 1.7316 - 2.563 0.521 - 178.1 1 2 1 0.003 16 0 0 0 8.78E+07 7.49E+07 - - - 6.7627 0.9992 221125_WJC_METTL3_EV_vs_WT_F04.16281.16281.3 9.34E-05 13/48 R.SKEAEAAFLNVYK.R "sp|Q13948|CASP_HUMAN,sp|P39880|CUX1_HUMAN,tr|A0A2R8Y852|A0A2R8Y852_HUMAN,tr|A0A2R8YDI1|A0A2R8YDI1_HUMAN" 4 1468.7562 1.98 49997 16281 3 1468.761093 490.5927 Protein CASP OS=Homo sapiens OX=9606 GN=CUX1 PE=1 SV=2 5.86 2872 - 1.84E+06 - - - 3.3348 - 2.719 0.448 - 207.6 1 2 1 0.0049 13 0 0 0 2.15E+07 1.09E+07 - - - 6.2454 0.9993 221125_WJC_METTL3_EV_vs_WT_F04.16282.16282.3 1.54E-06 13/48 R.SK[136.11]EAEAAFLNVYK[136.11].R "sp|Q13948|CASP_HUMAN,sp|P39880|CUX1_HUMAN,tr|A0A2R8Y852|A0A2R8Y852_HUMAN,tr|A0A2R8YDI1|A0A2R8YDI1_HUMAN" 4 1484.7846 2.01 49998 16282 3 1484.787332 495.9355 Protein CASP OS=Homo sapiens OX=9606 GN=CUX1 PE=1 SV=2 5.86 2872.1 - 924468 - - - 1.8434 - 2.484 0.392 - 162.6 1 2 1 0.0027 13 0 0 0 2.18E+07 1.09E+07 - - - 5.3766 0.9855 221125_WJC_METTL3_EV_vs_WT_F04.16283.16283.3 6.13E-06 Nov-52 M.ELPYGTLTDDEMR[166.11]R[166.11].L sp|Q86U44|MTA70_HUMAN 1 1714.8099 0.02 49999 16283 3 1714.813921 572.6106 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 4.32 2872.1 - 752396 - - - 2.3303 - 2.104 0.469 - 163 1 1 0 0.004 14 0 0 0 1.85E+05 8.14E+06 - - - 5.7446 0.9922 221125_WJC_METTL3_EV_vs_WT_F04.16285.16285.3 0.0277 Dec-44 K.WQTMIEAHVDVK.T "sp|P61247|RS3A_HUMAN,tr|H0Y8L7|H0Y8L7_HUMAN,tr|D6RED7|D6RED7_HUMAN,tr|D6RAS7|D6RAS7_HUMAN,tr|D6RB09|D6RB09_HUMAN,tr|E9PFI5|E9PFI5_HUMAN,tr|D6RAT0|D6RAT0_HUMAN,tr|D6RG13|D6RG13_HUMAN" 8 1455.718 0.85 50001 16285 3 1455.717876 486.2466 40S ribosomal protein S3a OS=Homo sapiens OX=9606 GN=RPS3A PE=1 SV=2 5.32 2872.4 - 516166 - - - -0.1092 - 1.994 0.135 - 154.3 1 2 0 -0.0002 12 0 0 0 2.60E+06 3.08E+06 - - - 1.958 1 221125_WJC_METTL3_EV_vs_WT_F04.16288.16288.2 4.55E-12 17/28 K.EAEDGIIAYDDC[160.03]GVK[136.11].L "sp|O75534|CSDE1_HUMAN,tr|E9PLT0|E9PLT0_HUMAN" 2 1661.7334 0.61 50004 16288 2 1661.734885 831.874 Cold shock domain-containing protein E1 OS=Homo sapiens OX=9606 GN=CSDE1 PE=1 SV=2 3.77 2872.8 - 488487 - - - 0.8834 - 3.333 0.691 - 1034.2 1 2 0 0.0015 15 0 0 0 1.84E+06 3.03E+06 - - - 7.104 0.9798 221125_WJC_METTL3_EV_vs_WT_F04.16289.16289.2 0.00493 24-Nov R.QQAEPWTPTANLK.M "sp|Q96AV8|E2F7_HUMAN,tr|F8VXV5|F8VXV5_HUMAN,tr|F8VSE7|F8VSE7_HUMAN" 3 1482.7467 0.57 50005 16289 2 1482.741003 742.3806 Transcription factor E2F7 OS=Homo sapiens OX=9606 GN=E2F7 PE=1 SV=3 6 2872.9 - 439725 - - - -3.8375 - 1.903 0.126 - 285.7 1 2 0 -0.0057 13 0 0 0 1.73E+06 3.04E+06 - - - 1.6212 0.9607 221125_WJC_METTL3_EV_vs_WT_F04.16292.16292.3 7.71E-07 Dec-68 H.MHIPTSGAPGSPGTLALR.S sp|Q96F45|ZN503_HUMAN 1 1761.9196 5.21 50008 16292 3 1761.927532 588.3138 Zinc finger protein 503 OS=Homo sapiens OX=9606 GN=ZNF503 PE=1 SV=1 9.52 2873.3 - 375708 - - - 4.5082 - 2.65 0.485 - 175.8 1 1 0 0.0079 18 0 0 0 1.39E+06 2.68E+05 - - - 6.3718 0.9311 221125_WJC_METTL3_EV_vs_WT_F04.16293.16293.2 2.00E-05 28-Aug K.EGYVPQEEVPVYENK[136.11].Y sp|Q9BRP8|PYM1_HUMAN 1 1786.8505 0.55 50009 16293 2 1787.860687 894.4325 Partner of Y14 and mago OS=Homo sapiens OX=9606 GN=PYM1 PE=1 SV=1 4.09 2873.4 - 356180 - - - 565.3472 - 1.72 0.532 - 138.3 1 2 0 1.0102 15 0 0 0 1.11E+06 2.02E+06 - - - 3.9865 0.9996 221125_WJC_METTL3_EV_vs_WT_F04.16295.16295.2 0.00141 28-Aug R.MDSPSATVVSAVQSR.C sp|Q6KB66|K2C80_HUMAN 1 1533.7457 2.44 50011 16295 2 1533.744126 767.8801 "Keratin, type II cytoskeletal 80 OS=Homo sapiens OX=9606 GN=KRT80 PE=1 SV=2" 5.59 2873.7 - 181399 - - - -1.0308 - 1.759 0.397 - 128.3 1 2 0 -0.0016 15 0 0 0 4.26E+06 1.74E+06 - - - 3.3612 0.9995 221125_WJC_METTL3_EV_vs_WT_F04.16298.16298.2 0.00519 20-Nov K.NNIPYFETSAK[136.11].E "sp|P51149|RAB7A_HUMAN,tr|C9J4V0|C9J4V0_HUMAN,tr|A0A6Q8PH84|A0A6Q8PH84_HUMAN,tr|C9J8S3|C9J8S3_HUMAN,tr|A0A6Q8PGE6|A0A6Q8PGE6_HUMAN,tr|A0A6Q8PG52|A0A6Q8PG52_HUMAN" 6 1290.6336 1.27 50013 16298 2 1290.635407 646.3241 Ras-related protein Rab-7a OS=Homo sapiens OX=9606 GN=RAB7A PE=1 SV=1 6 2874 - 5.17E+06 - - - 1.4257 - 1.702 0.408 - 362.1 1 2 0 0.0018 11 0 0 0 4.17E+07 3.28E+07 - - - 3.4926 0.9993 221125_WJC_METTL3_EV_vs_WT_F04.16300.16300.2 0.0301 16-Sep K.TLLDIDNTR.M sp|P35527|K1C9_HUMAN 1 1059.556 999 50015 16300 2 1059.557701 530.7853 "Keratin, type I cytoskeletal 9 OS=Homo sapiens OX=9606 GN=KRT9 PE=1 SV=3" 4.21 2874.3 - 1.01E+06 - - - 1.5695 - 1.781 0.343 - 225.2 1 2 0 0.0017 9 0 0 0 3.35E+07 0.00E+00 - - - 3.2437 0.9999 221125_WJC_METTL3_EV_vs_WT_F04.16301.16301.3 0.000341 Dec-40 R.KFLDGIYVSEK.G "sp|P32969|RL9_HUMAN,tr|H0Y9R4|H0Y9R4_HUMAN,tr|D6RAN4|D6RAN4_HUMAN,tr|H0Y9V9|H0Y9V9_HUMAN,tr|A0A2R8Y5Y7|A0A2R8Y5Y7_HUMAN" 5 1297.6918 0.71 50016 16301 3 1297.693006 433.5712 60S ribosomal protein L9 OS=Homo sapiens OX=9606 GN=RPL9 PE=1 SV=1 6.07 2874.4 - 970893 - - - 0.9263 - 2.191 0.423 - 206.5 1 2 0 0.0012 11 0 0 0 2.09E+07 2.96E+07 - - - 5.4839 0.9999 221125_WJC_METTL3_EV_vs_WT_F04.16303.16303.2 7.72E-06 22-Nov K.QNSIGSYVLQEK.S sp|Q8IYH5|ZZZ3_HUMAN 1 1364.6936 1.8 50018 16303 2 1364.69514 683.3541 ZZ-type zinc finger-containing protein 3 OS=Homo sapiens OX=9606 GN=ZZZ3 PE=1 SV=1 6 2874.6 - 802084 - - - 1.1321 - 2.336 0.521 - 473.3 1 2 0 0.0015 12 0 0 0 4.23E+06 2.35E+06 - - - 5.121 1 221125_WJC_METTL3_EV_vs_WT_F04.16307.16307.3 2.73E-07 17/52 R.NTC[160.03]EAVVLGTLHPR[166.11].T "sp|Q9NQT4|EXOS5_HUMAN,tr|M0R050|M0R050_HUMAN" 2 1575.8067 0.82 50022 16307 3 1575.807519 526.2762 Exosome complex component RRP46 OS=Homo sapiens OX=9606 GN=EXOSC5 PE=1 SV=1 6.74 2875 - 555860 - - - 0.5318 - 3.24 0.558 - 418.8 1 2 0 0.0008 14 0 0 0 4.51E+06 5.53E+06 - - - 7.885 0.9999 221125_WJC_METTL3_EV_vs_WT_F04.16309.16309.3 0.014 Nov-44 K.KEFGPVVIDYGK.V "sp|Q14204|DYHC1_HUMAN,tr|A0A7P0T8N2|A0A7P0T8N2_HUMAN,tr|A0A7P0T9C4|A0A7P0T9C4_HUMAN,tr|A0A7P0TBJ7|A0A7P0TBJ7_HUMAN,tr|A0A804HHY6|A0A804HHY6_HUMAN,tr|A0A7P0T9K2|A0A7P0T9K2_HUMAN,tr|A0A7P0TB64|A0A7P0TB64_HUMAN,tr|A0A2R8Y706|A0A2R8Y706_HUMAN,tr|A0A7P0T916|A0A7P0T916_HUMAN,tr|A0A7P0TB75|A0A7P0TB75_HUMAN,tr|A0A7P0T8W5|A0A7P0T8W5_HUMAN,tr|A0A7P0T9S3|A0A7P0T9S3_HUMAN,tr|A0A7P0TAF3|A0A7P0TAF3_HUMAN,tr|A0A7P0T9F1|A0A7P0T9F1_HUMAN,tr|A0A7P0TAW9|A0A7P0TAW9_HUMAN,tr|A0A2R8YGC7|A0A2R8YGC7_HUMAN,tr|A0A7P0TA13|A0A7P0TA13_HUMAN,tr|A0A7P0T934|A0A7P0T934_HUMAN,tr|A0A7P0TAV5|A0A7P0TAV5_HUMAN,tr|A0A7P0T9Y3|A0A7P0T9Y3_HUMAN,tr|A0A7P0T7V5|A0A7P0T7V5_HUMAN,tr|A0A7P0T9R4|A0A7P0T9R4_HUMAN,tr|A0A2R8Y5T0|A0A2R8Y5T0_HUMAN,tr|A0A7P0T990|A0A7P0T990_HUMAN,tr|A0A7P0T942|A0A7P0T942_HUMAN,tr|A0A2R8YFZ7|A0A2R8YFZ7_HUMAN,tr|A0A7P0T825|A0A7P0T825_HUMAN,tr|A0A2R8Y6H2|A0A2R8Y6H2_HUMAN,tr|A0A7P0TBC9|A0A7P0TBC9_HUMAN,tr|A0A7P0TAM4|A0A7P0TAM4_HUMAN" 30 1350.7184 1.13 50024 16309 3 1350.716388 451.2467 Cytoplasmic dynein 1 heavy chain 1 OS=Homo sapiens OX=9606 GN=DYNC1H1 PE=1 SV=5 6.07 2875.2 - 419565 - - - -1.4548 - 2.046 0.417 - 185.1 1 2 0 -0.002 12 0 0 0 2.11E+06 1.87E+06 - - - 5.1729 1 221125_WJC_METTL3_EV_vs_WT_F04.16311.16311.2 6.06E-10 17/30 R.VFDKDGNGYISAAELR.H "sp|P0DP25|CALM3_HUMAN,sp|P0DP23|CALM1_HUMAN,sp|P0DP24|CALM2_HUMAN,tr|G3V361|G3V361_HUMAN,tr|A0A590UJI2|A0A590UJI2_HUMAN,tr|Q96HY3|Q96HY3_HUMAN,tr|E7EMB3|E7EMB3_HUMAN" 7 1753.8635 1.21 50026 16311 2 1753.864733 877.939 Calmodulin-3 OS=Homo sapiens OX=9606 GN=CALM3 PE=1 SV=1 4.56 2875.5 - 359663 - - - 0.695 - 3.555 0.615 - 1083.8 1 2 1 0.0012 16 0 0 0 2.81E+06 2.32E+06 - - - 6.7013 1 221125_WJC_METTL3_EV_vs_WT_F04.16312.16312.2 8.69E-08 20/30 R.VFDK[136.11]DGNGYISAAELR[166.11].H "sp|P0DP25|CALM3_HUMAN,sp|P0DP23|CALM1_HUMAN,sp|P0DP24|CALM2_HUMAN,tr|G3V361|G3V361_HUMAN,tr|A0A590UJI2|A0A590UJI2_HUMAN,tr|Q96HY3|Q96HY3_HUMAN,tr|E7EMB3|E7EMB3_HUMAN" 7 1771.886 1.21 50027 16312 2 1771.887397 886.9503 Calmodulin-3 OS=Homo sapiens OX=9606 GN=CALM3 PE=1 SV=1 4.56 2875.6 - 335146 - - - 0.7975 - 3.842 0.665 - 1532 1 2 1 0.0014 16 0 0 0 2.81E+06 2.32E+06 - - - 7.2614 1 221125_WJC_METTL3_EV_vs_WT_F04.16324.16324.2 0.000379 15/20 R.KFLDGIYVSEK.G "sp|P32969|RL9_HUMAN,tr|H0Y9R4|H0Y9R4_HUMAN,tr|D6RAN4|D6RAN4_HUMAN,tr|H0Y9V9|H0Y9V9_HUMAN,tr|A0A2R8Y5Y7|A0A2R8Y5Y7_HUMAN" 5 1297.6918 0.77 50037 16324 2 1297.697021 649.8532 60S ribosomal protein L9 OS=Homo sapiens OX=9606 GN=RPL9 PE=1 SV=1 6.07 2877.2 - 689436 - - - 4.0202 - 3.2 0.546 - 719.3 1 2 0 0.0052 11 0 0 0 5.39E+06 6.98E+06 - - - 6.2187 1 221125_WJC_METTL3_EV_vs_WT_F04.16325.16325.3 0.000176 Dec-64 R.MYIHPDSPATGEQWMSK[136.11].V sp|O15119|TBX3_HUMAN 1 1984.8903 0.88 50038 16325 3 1984.892527 662.6374 T-box transcription factor TBX3 OS=Homo sapiens OX=9606 GN=TBX3 PE=1 SV=4 5.3 2877.3 - 629162 - - - 1.1376 - 2.812 0.509 - 211.3 1 2 0 0.0023 17 0 0 0 5.79E+06 6.56E+06 - - - 6.8262 0.9999 221125_WJC_METTL3_EV_vs_WT_F04.16326.16326.3 1.76E-05 13/44 K.TTGIVETHFTFK.D "sp|P63096|GNAI1_HUMAN,sp|P04899|GNAI2_HUMAN,sp|P08754|GNAI3_HUMAN,sp|P09471|GNAO_HUMAN,tr|A0A1W2PP38|A0A1W2PP38_HUMAN,tr|A0A3B3ITM0|A0A3B3ITM0_HUMAN,tr|H3BTM2|H3BTM2_HUMAN" 7 1379.7085 0.57 50039 16326 3 1379.710486 460.9101 Guanine nucleotide-binding protein G(i) subunit alpha-1 OS=Homo sapiens OX=9606 GN=GNAI1 PE=1 SV=2 6.41 2877.4 - 513920 - - - 1.4278 - 2.586 0.415 - 197.8 1 2 0 0.002 12 0 0 0 1.33E+07 2.35E+07 - - - 5.7999 0.9997 221125_WJC_METTL3_EV_vs_WT_F04.16330.16330.3 3.71E-08 13/52 R.FEDPRDAEDAIYGR.N "sp|Q13242|SRSF9_HUMAN,tr|H0YIB4|H0YIB4_HUMAN,tr|S4R3G0|S4R3G0_HUMAN" 3 1652.7431 1.92 50043 16330 3 1652.737951 551.9216 Serine\arginine-rich splicing factor 9 OS=Homo sapiens OX=9606 GN=SRSF9 PE=1 SV=1 4.11 2877.9 - 333433 - - - -3.0936 - 2.164 0.594 - 130.4 1 2 1 -0.0051 14 0 0 0 1.45E+07 7.56E+06 - - - 7.2126 0.9998 221125_WJC_METTL3_EV_vs_WT_F04.16331.16331.2 5.57E-05 22-Oct K.QNSIGSYVLQEK[136.11].S sp|Q8IYH5|ZZZ3_HUMAN 1 1372.7078 1.74 50044 16331 2 1372.705978 687.3612 ZZ-type zinc finger-containing protein 3 OS=Homo sapiens OX=9606 GN=ZZZ3 PE=1 SV=1 6 2878.1 - 254457 - - - -1.3237 - 2.348 0.476 - 407.1 1 2 0 -0.0018 12 0 0 0 4.23E+06 2.44E+06 - - - 4.802 0.9985 221125_WJC_METTL3_EV_vs_WT_F04.16333.16333.3 0.127 Sep-36 R.KELDILLQEK.L "sp|Q9H2U1|DHX36_HUMAN,tr|A0A0G2JQU7|A0A0G2JQU7_HUMAN" 2 1227.7075 2.41 50046 16333 3 1227.708608 410.2431 ATP-dependent DNA\RNA helicase DHX36 OS=Homo sapiens OX=9606 GN=DHX36 PE=1 SV=2 4.68 2878.3 - 229554 - - - 0.94 - 1.93 0.233 - 100.8 1 2 0 0.0012 10 0 0 0 1.24E+06 5.15E+05 - - - 3.0576 0.9797 221125_WJC_METTL3_EV_vs_WT_F04.16339.16339.2 0.0444 14-Sep K.DLKDYFSK.F "sp|Q14103|HNRPD_HUMAN,tr|H0Y8G5|H0Y8G5_HUMAN,tr|D6RF44|D6RF44_HUMAN,tr|D6RD83|D6RD83_HUMAN,tr|D6RBQ9|D6RBQ9_HUMAN,tr|D6RAF8|D6RAF8_HUMAN,tr|H0YA96|H0YA96_HUMAN" 7 1014.5022 0.76 50051 16339 2 1014.504097 508.2584 Heterogeneous nuclear ribonucleoprotein D0 OS=Homo sapiens OX=9606 GN=HNRNPD PE=1 SV=1 5.96 2879.1 - 3.67E+06 - - - 1.8581 - 1.559 0.286 - 297.2 1 2 1 0.0019 8 0 0 0 1.79E+07 2.34E+07 - - - 2.492 0.9997 221125_WJC_METTL3_EV_vs_WT_F04.16340.16340.2 5.31E-06 22-Sep R.QQQPPPETFDFK.L "sp|Q14203|DCTN1_HUMAN,tr|A0A804CDA6|A0A804CDA6_HUMAN,tr|E7EX90|E7EX90_HUMAN,tr|A0A7P0Z4C3|A0A7P0Z4C3_HUMAN,tr|Q6AWB1|Q6AWB1_HUMAN" 5 1460.6936 1.47 50052 16340 2 1460.695728 731.3541 Dynactin subunit 1 OS=Homo sapiens OX=9606 GN=DCTN1 PE=1 SV=3 4.37 2879.2 - 1.17E+06 - - - 1.4603 - 2.011 0.449 - 310 1 2 0 0.0021 12 0 0 0 7.59E+07 5.17E+07 - - - 4.1949 0.9998 221125_WJC_METTL3_EV_vs_WT_F04.16343.16343.2 0.000214 14/20 R.K[136.11]FLDGIYVSEK[136.11].G "sp|P32969|RL9_HUMAN,tr|H0Y9R4|H0Y9R4_HUMAN,tr|D6RAN4|D6RAN4_HUMAN,tr|H0Y9V9|H0Y9V9_HUMAN,tr|A0A2R8Y5Y7|A0A2R8Y5Y7_HUMAN" 5 1313.7202 0.76 50055 16343 2 1313.722696 657.8674 60S ribosomal protein L9 OS=Homo sapiens OX=9606 GN=RPL9 PE=1 SV=1 6.07 2879.4 - 1.69E+06 - - - 1.8969 - 2.718 0.441 - 468.8 1 2 0 0.0025 11 0 0 0 5.39E+06 7.14E+06 - - - 5.0024 0.9994 221125_WJC_METTL3_EV_vs_WT_F04.16344.16344.2 0.000106 15/26 K.AINQQTGAFVEISR[166.11].Q "sp|Q92945|FUBP2_HUMAN,tr|M0R3J3|M0R3J3_HUMAN,tr|M0R0C6|M0R0C6_HUMAN,tr|A0A087WTP3|A0A087WTP3_HUMAN" 4 1542.803 1.21 50056 16344 2 1542.807923 772.4088 Far upstream element-binding protein 2 OS=Homo sapiens OX=9606 GN=KHSRP PE=1 SV=4 6.05 2879.5 - 1.32E+06 - - - 3.2065 - 2.965 0.458 - 831.8 1 2 0 0.0049 14 0 0 0 2.13E+07 1.75E+07 - - - 5.1497 0.9997 221125_WJC_METTL3_EV_vs_WT_F04.16345.16345.2 6.18E-06 14/26 K.AINQQTGAFVEISR.Q "sp|Q92945|FUBP2_HUMAN,tr|M0R3J3|M0R3J3_HUMAN,tr|M0R0C6|M0R0C6_HUMAN,tr|A0A087WTP3|A0A087WTP3_HUMAN" 4 1532.7947 1.21 50057 16345 2 1532.798491 767.4046 Far upstream element-binding protein 2 OS=Homo sapiens OX=9606 GN=KHSRP PE=1 SV=4 6.05 2879.5 - 1.25E+06 - - - 2.4693 - 2.99 0.484 - 653.3 1 2 0 0.0038 14 0 0 0 2.13E+07 1.75E+07 - - - 5.3632 0.9985 221125_WJC_METTL3_EV_vs_WT_F04.16346.16346.3 0.0163 Dec-48 K.EFNPTK[136.11]PLLSVNK[136.11].S "sp|Q8WWM7|ATX2L_HUMAN,tr|H3BUF6|H3BUF6_HUMAN" 2 1501.8475 1.47 50058 16346 3 1501.853011 501.6231 Ataxin-2-like protein OS=Homo sapiens OX=9606 GN=ATXN2L PE=1 SV=2 8.69 2879.6 - 1.06E+06 - - - 3.6502 - 2.08 0.347 - 163 1 2 0 0.0055 13 0 0 0 5.38E+07 3.65E+07 - - - 4.3929 1 221125_WJC_METTL3_EV_vs_WT_F04.16347.16347.3 9.16E-10 21/64 R.MYIHPDSPATGEQWMSK.V sp|O15119|TBX3_HUMAN 1 1976.8761 0.89 50059 16347 3 1976.882621 659.966 T-box transcription factor TBX3 OS=Homo sapiens OX=9606 GN=TBX3 PE=1 SV=4 5.3 2879.8 - 849185 - - - 3.3143 - 3.828 0.616 - 752.6 1 2 0 0.0066 17 0 0 0 5.79E+06 6.48E+06 - - - 8.7971 1 221125_WJC_METTL3_EV_vs_WT_F04.16348.16348.3 2.14E-06 17/48 K.YFTC[160.03]DEGHGIFVR.Q "sp|Q14203|DCTN1_HUMAN,tr|C9JTE5|C9JTE5_HUMAN,tr|A0A804CDA6|A0A804CDA6_HUMAN,tr|C9JJN7|C9JJN7_HUMAN,tr|E7EX90|E7EX90_HUMAN,tr|C9JJD0|C9JJD0_HUMAN,tr|A0A7P0Z4C3|A0A7P0Z4C3_HUMAN,tr|Q6AWB1|Q6AWB1_HUMAN,tr|C9JZA4|C9JZA4_HUMAN,tr|E9PCY0|E9PCY0_HUMAN,tr|C9JKG6|C9JKG6_HUMAN" 11 1599.714 0.86 50060 16348 3 1599.716362 534.2453 Dynactin subunit 1 OS=Homo sapiens OX=9606 GN=DCTN1 PE=1 SV=3 5.32 2879.9 - 645292 - - - 1.4684 - 2.913 0.637 - 324.2 1 2 0 0.0023 13 0 0 0 4.12E+06 4.81E+06 - - - 8.5401 0.9988 221125_WJC_METTL3_EV_vs_WT_F04.16349.16349.3 0.000113 Dec-44 K.LKEVFSIAGTVK.R "sp|Q9P2K5|MYEF2_HUMAN,tr|A0A0A0MR39|A0A0A0MR39_HUMAN,tr|A0A087WUT0|A0A087WUT0_HUMAN,tr|H0YN19|H0YN19_HUMAN,tr|A0A0A0MQW0|A0A0A0MQW0_HUMAN" 5 1290.7547 1.36 50061 16349 3 1290.757815 431.2589 Myelin expression factor 2 OS=Homo sapiens OX=9606 GN=MYEF2 PE=1 SV=3 8.59 2880 - 620847 - - - 2.3839 - 2.212 0.398 - 184 1 2 1 0.0031 12 0 0 0 2.99E+06 2.20E+06 - - - 5.177 0.9999 221125_WJC_METTL3_EV_vs_WT_F04.16352.16352.3 8.72E-07 14/60 K.IINADSEDPK[136.11]YIINVK[136.11].Q "sp|P35998|PRS7_HUMAN,tr|C9JX88|C9JX88_HUMAN,tr|C9JLS9|C9JLS9_HUMAN" 3 1847.0011 1.28 50064 16352 3 1847.00472 616.6743 26S proteasome regulatory subunit 7 OS=Homo sapiens OX=9606 GN=PSMC2 PE=1 SV=3 4.56 2880.4 - 384003 - - - 1.9437 - 2.686 0.577 - 190.6 1 2 1 0.0036 16 0 0 0 3.48E+06 2.71E+06 - - - 7.5072 0.9998 221125_WJC_METTL3_EV_vs_WT_F04.16354.16354.3 0.00105 14/40 K.SLLSNLDEVKK.E sp|Q8WUM4|PDC6I_HUMAN 1 1244.6976 0.98 50066 16354 3 1244.698924 415.9065 Programmed cell death 6-interacting protein OS=Homo sapiens OX=9606 GN=PDCD6IP PE=1 SV=1 5.79 2880.7 - 337530 - - - 1.0501 - 1.855 0.396 - 197.5 1 2 0 0.0013 11 0 0 0 7.22E+06 7.37E+06 - - - 4.71 0.9999 221125_WJC_METTL3_EV_vs_WT_F04.16355.16355.2 7.77E-06 28-Dec K.ASIGQSPGLPSTTFK[136.11].L sp|Q5VT52|RPRD2_HUMAN 1 1497.7919 1.57 50067 16355 2 1497.791333 749.9032 Regulation of nuclear pre-mRNA domain-containing protein 2 OS=Homo sapiens OX=9606 GN=RPRD2 PE=1 SV=1 8.8 2880.8 - 247811 - - - -0.3512 - 2.778 0.536 - 372.6 1 2 0 -0.0005 15 0 0 0 8.06E+06 5.14E+06 - - - 5.5117 1 221125_WJC_METTL3_EV_vs_WT_F04.16357.16357.2 1.22E-06 14/30 F.VTLDEVGDEEDSELQK.L tr|A8MXP9|A8MXP9_HUMAN 1 1804.8214 1.8 50069 16357 2 1804.824734 903.418 Matrin-3 OS=Homo sapiens OX=9606 GN=MATR3 PE=1 SV=1 3.66 2881.1 - 232060 - - - 1.8284 - 3.347 0.615 - 526.5 1 1 0 0.0033 16 0 0 0 2.92E+06 1.63E+06 - - - 6.5524 1 221125_WJC_METTL3_EV_vs_WT_F04.16361.16361.2 5.01E-10 13/22 K.NNPVMSLQDQVR[166.11].F "sp|Q7LGA3|HS2ST_HUMAN,tr|K7EP71|K7EP71_HUMAN" 2 1409.6961 1.19 50072 16361 2 1409.697438 705.8553 Heparan sulfate 2-O-sulfotransferase 1 OS=Homo sapiens OX=9606 GN=HS2ST1 PE=1 SV=1 5.84 2881.6 - 734945 - - - 0.9718 - 2.634 0.624 - 768.6 1 2 0 0.0014 12 0 0 0 1.35E+07 1.14E+07 - - - 6.1977 1 221125_WJC_METTL3_EV_vs_WT_F04.16362.16362.2 8.40E-07 13/24 R.FSGSGSGTDFTLK.L "sp|A2NJV5|KV229_HUMAN,sp|A0A087WW87|KV240_HUMAN,sp|P06310|KV230_HUMAN,sp|A0A075B6S2|KVD29_HUMAN,sp|P01614|KVD40_HUMAN,sp|P01615|KVD28_HUMAN,sp|A0A075B6S6|KVD30_HUMAN,sp|A0A075B6P5|KV228_HUMAN,sp|A0A0A0MRZ7|KVD26_HUMAN" 9 1302.6092 143.5 50073 16362 2 1302.612308 652.3119 Immunoglobulin kappa variable 2-29 OS=Homo sapiens OX=9606 GN=IGKV2-29 PE=3 SV=2 5.84 2881.6 - 2.34E+06 - - - 2.3891 - 2.885 0.61 - 336 1 2 0 0.0031 13 0 0 0 1.41E+07 9.84E+04 - - - 6.2648 0.9997 221125_WJC_METTL3_EV_vs_WT_F04.16363.16363.3 1.59E-06 Dec-48 K.EFNPTKPLLSVNK.S "sp|Q8WWM7|ATX2L_HUMAN,tr|H3BUF6|H3BUF6_HUMAN" 2 1485.8191 1.49 50074 16363 3 1485.825314 496.2803 Ataxin-2-like protein OS=Homo sapiens OX=9606 GN=ATXN2L PE=1 SV=2 8.69 2881.7 - 2.12E+06 - - - 4.1627 - 2.268 0.519 - 169.7 1 2 0 0.0062 13 0 0 0 5.38E+07 3.62E+07 - - - 6.5449 0.9999 221125_WJC_METTL3_EV_vs_WT_F04.16364.16364.3 0.000715 13/40 K.SLLSNLDEVK[136.11]K[136.11].E sp|Q8WUM4|PDC6I_HUMAN 1 1260.726 0.97 50075 16364 3 1260.727882 421.2493 Programmed cell death 6-interacting protein OS=Homo sapiens OX=9606 GN=PDCD6IP PE=1 SV=1 5.79 2881.8 - 1.17E+06 - - - 1.4793 - 2.489 0.38 - 178.5 1 2 0 0.0019 11 0 0 0 7.02E+06 7.26E+06 - - - 5.3666 0.9997 221125_WJC_METTL3_EV_vs_WT_F04.16366.16366.3 4.97E-06 14/52 R.GC[160.03]GVVEFKDEEFVK.K "sp|Q9P2K5|MYEF2_HUMAN,tr|A0A0A0MR39|A0A0A0MR39_HUMAN,tr|A0A0A0MQW0|A0A0A0MQW0_HUMAN" 3 1641.7709 1.3 50077 16366 3 1641.774667 548.2642 Myelin expression factor 2 OS=Homo sapiens OX=9606 GN=MYEF2 PE=1 SV=3 4.41 2881.9 - 731170 - - - 2.3194 - 2.398 0.502 - 201.2 1 2 1 0.0038 14 0 0 0 6.82E+06 5.25E+06 - - - 6.4601 1 221125_WJC_METTL3_EV_vs_WT_F04.16367.16367.2 2.84E-08 18/28 L.AAATQSLSMPASLGR[166.11].M "sp|P43243|MATR3_HUMAN,tr|A0A1B0GX04|A0A1B0GX04_HUMAN,tr|D6RBS2|D6RBS2_HUMAN,tr|A8MXP9|A8MXP9_HUMAN,tr|D6R991|D6R991_HUMAN,tr|D6REK4|D6REK4_HUMAN,tr|D6R9F3|D6R9F3_HUMAN,tr|A0A0R4J2E8|A0A0R4J2E8_HUMAN,tr|D6RB45|D6RB45_HUMAN,tr|D6RCM3|D6RCM3_HUMAN,tr|D6R8Z5|D6R8Z5_HUMAN,tr|D6REM6|D6REM6_HUMAN" 12 1469.7536 0.97 50078 16367 2 1469.763832 735.8841 Matrin-3 OS=Homo sapiens OX=9606 GN=MATR3 PE=1 SV=2 9.79 2882 - 706302 - - - 6.9733 - 3.628 0.583 - 1214.8 1 1 0 0.0103 15 0 0 0 1.70E+07 1.75E+07 - - - 6.5121 0.9998 221125_WJC_METTL3_EV_vs_WT_F04.16368.16368.3 0.0263 Jul-52 K.NSVTPDMMEEMYK[136.11]K[136.11].A "sp|P46777|RL5_HUMAN,tr|A0A2R8Y6J3|A0A2R8Y6J3_HUMAN" 2 1717.7696 0.91 50079 16368 3 1717.772071 573.5971 60S ribosomal protein L5 OS=Homo sapiens OX=9606 GN=RPL5 PE=1 SV=3 4.68 2882.1 - 668642 - - - 1.4298 - 2.192 0.367 - 56.9 1 2 0 0.0025 14 0 0 0 2.91E+06 3.20E+06 - - - 4.7167 0.9998 221125_WJC_METTL3_EV_vs_WT_F04.16370.16370.3 0.000989 Oct-36 K.DC[160.03]PLQFHDFK.S "sp|O75528|TADA3_HUMAN,tr|C9JMS0|C9JMS0_HUMAN" 2 1305.5812 0.99 50081 16370 3 1305.583545 436.201 Transcriptional adapter 3 OS=Homo sapiens OX=9606 GN=TADA3 PE=1 SV=1 5.21 2882.4 - 547431 - - - 1.79 - 1.699 0.428 - 136.3 1 2 0 0.0023 10 0 0 0 4.07E+06 4.10E+06 - - - 4.8591 0.9995 221125_WJC_METTL3_EV_vs_WT_F04.16372.16372.2 0.000259 22-Aug R.DC[160.03]GTSVPQGLLK.A sp|Q9H9A6|LRC40_HUMAN 1 1273.6336 2.22 50083 16372 2 1273.63545 637.8241 Leucine-rich repeat-containing protein 40 OS=Homo sapiens OX=9606 GN=LRRC40 PE=1 SV=1 5.83 2882.6 - 456068 - - - 1.4235 - 1.8 0.417 - 186.5 1 2 0 0.0018 12 0 0 0 9.78E+06 4.40E+06 - - - 3.667 0.9992 221125_WJC_METTL3_EV_vs_WT_F04.16374.16374.2 0.00304 20-Jun R.DTEQVDNWMSK[136.11].Q "sp|Q13813|SPTN1_HUMAN,tr|A0A0D9SF54|A0A0D9SF54_HUMAN,tr|A0A0D9SGF6|A0A0D9SGF6_HUMAN" 3 1359.5856 1.72 50085 16374 2 1359.588253 680.8001 "Spectrin alpha chain, non-erythrocytic 1 OS=Homo sapiens OX=9606 GN=SPTAN1 PE=1 SV=3" 4.03 2882.9 - 370274 - - - 1.9285 - 1.391 0.459 - 56.3 1 2 0 0.0026 11 0 0 0 3.13E+06 1.82E+06 - - - 3.3231 1 221125_WJC_METTL3_EV_vs_WT_F04.16375.16375.2 3.06E-11 18/30 K.SPVDYGTSAGVWSQDK[136.11].W sp|Q9BYJ9|YTHD1_HUMAN 1 1703.7882 2.31 50086 16375 2 1703.797375 852.9014 YTH domain-containing family protein 1 OS=Homo sapiens OX=9606 GN=YTHDF1 PE=1 SV=1 4.21 2883 - 359018 - - - 5.3675 - 3.287 0.701 - 1239.5 1 2 0 0.0091 16 0 0 0 8.59E+06 3.72E+06 - - - 7.1413 0.9998 221125_WJC_METTL3_EV_vs_WT_F04.16379.16379.2 7.00E-05 Jun-34 R.ATQFTGATGAIMTTETTK[136.11].T sp|Q14126|DSG2_HUMAN 1 1836.9019 0.44 50090 16379 2 1836.903979 919.4582 Desmoglein-2 OS=Homo sapiens OX=9606 GN=DSG2 PE=1 SV=2 6.05 2883.5 - 150829 - - - 1.1432 - 1.895 0.554 - 77.6 1 2 0 0.0021 18 0 0 0 5.38E+05 1.23E+06 - - - 4.7037 0.9996 221125_WJC_METTL3_EV_vs_WT_F04.16381.16381.3 2.21E-05 14/40 K.FAAQELIEVK[136.11]R[166.11].G "sp|Q86U44|MTA70_HUMAN,tr|F5H6D8|F5H6D8_HUMAN,tr|H0YFV6|H0YFV6_HUMAN,tr|B4DTN4|B4DTN4_HUMAN" 4 1320.7521 0 50091 16381 3 1320.75412 441.258 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 6.14 2883.8 - 753740 - - - 1.5627 - 2.364 0.298 - 168.1 1 2 0 0.0021 11 0 0 0 9.21E+04 1.97E+07 - - - 4.306 0.9997 221125_WJC_METTL3_EV_vs_WT_F04.16382.16382.2 0.00235 22-Oct R.NELEIPGQYDGR.G sp|P78527|PRKDC_HUMAN 1 1389.6525 1.19 50092 16382 2 1389.652232 695.8335 DNA-dependent protein kinase catalytic subunit OS=Homo sapiens OX=9606 GN=PRKDC PE=1 SV=3 4.14 2883.9 - 162327 - - - -0.1626 - 2.573 0.257 - 399.2 1 2 0 -0.0002 12 0 0 0 5.40E+06 4.55E+06 - - - 3.4258 1 221125_WJC_METTL3_EV_vs_WT_F04.16383.16383.2 3.91E-10 16/28 L.AAATQSLSMPASLGR.M "sp|P43243|MATR3_HUMAN,tr|A0A1B0GX04|A0A1B0GX04_HUMAN,tr|D6RBS2|D6RBS2_HUMAN,tr|A8MXP9|A8MXP9_HUMAN,tr|D6R991|D6R991_HUMAN,tr|D6REK4|D6REK4_HUMAN,tr|D6R9F3|D6R9F3_HUMAN,tr|A0A0R4J2E8|A0A0R4J2E8_HUMAN,tr|D6RB45|D6RB45_HUMAN,tr|D6RCM3|D6RCM3_HUMAN,tr|D6R8Z5|D6R8Z5_HUMAN,tr|D6REM6|D6REM6_HUMAN" 12 1459.7453 0.97 50093 16383 2 1459.748398 730.8799 Matrin-3 OS=Homo sapiens OX=9606 GN=MATR3 PE=1 SV=2 9.79 2883.9 - 2.46E+06 - - - 2.1134 - 3.499 0.641 - 924.8 1 1 0 0.0031 15 0 0 0 1.70E+07 1.76E+07 - - - 6.8537 1 221125_WJC_METTL3_EV_vs_WT_F04.16384.16384.3 4.86E-07 18/56 K.LQISHEAAAC[160.03]ITGLR[166.11].A sp|Q08211|DHX9_HUMAN 1 1648.8594 1.12 50094 16384 3 1648.862456 550.6271 ATP-dependent RNA helicase A OS=Homo sapiens OX=9606 GN=DHX9 PE=1 SV=4 6.74 2884 - 1.60E+06 - - - 1.8261 - 3.248 0.562 - 411.6 1 2 0 0.003 15 0 0 0 9.85E+06 8.76E+06 - - - 7.8788 1 221125_WJC_METTL3_EV_vs_WT_F04.16386.16386.3 1.31E-08 15/56 K.LQISHEAAAC[160.03]ITGLR.A sp|Q08211|DHX9_HUMAN 1 1638.8512 0.98 50096 16386 3 1638.855317 547.291 ATP-dependent RNA helicase A OS=Homo sapiens OX=9606 GN=DHX9 PE=1 SV=4 6.74 2884.1 - 1.32E+06 - - - 2.5274 - 3.269 0.569 - 292.8 1 2 0 0.0041 15 0 0 0 7.73E+06 7.85E+06 - - - 7.9734 0.9998 221125_WJC_METTL3_EV_vs_WT_F04.16387.16387.2 1.64E-07 13/28 K.ASIGQSPGLPSTTFK.L sp|Q5VT52|RPRD2_HUMAN 1 1489.7777 1.57 50097 16387 2 1489.780031 745.8961 Regulation of nuclear pre-mRNA domain-containing protein 2 OS=Homo sapiens OX=9606 GN=RPRD2 PE=1 SV=1 8.8 2884.2 - 1.00E+06 - - - 1.5922 - 2.968 0.534 - 399.9 1 2 0 0.0024 15 0 0 0 8.06E+06 5.14E+06 - - - 5.659 0.9999 221125_WJC_METTL3_EV_vs_WT_F04.16388.16388.3 5.42E-07 Nov-52 R.FEDPR[166.11]DAEDAIYGR[166.11].N "sp|Q13242|SRSF9_HUMAN,tr|H0YIB4|H0YIB4_HUMAN,tr|S4R3G0|S4R3G0_HUMAN" 3 1672.7596 2.02 50098 16388 3 1672.761196 558.5938 Serine\arginine-rich splicing factor 9 OS=Homo sapiens OX=9606 GN=SRSF9 PE=1 SV=1 4.11 2884.3 - 667438 - - - 0.9517 - 2.023 0.565 - 105.3 1 2 1 0.0016 14 0 0 0 1.44E+07 7.17E+06 - - - 6.7112 0.9999 221125_WJC_METTL3_EV_vs_WT_F04.16389.16389.3 0.00135 19/48 K.NR[166.11]EPVQLETLSIR[166.11].G "sp|P62314|SMD1_HUMAN,tr|J3QLI9|J3QLI9_HUMAN" 2 1573.8691 2.2 50099 16389 3 1573.872178 525.6303 Small nuclear ribonucleoprotein Sm D1 OS=Homo sapiens OX=9606 GN=SNRPD1 PE=1 SV=1 6.14 2884.4 - 617176 - - - 1.9589 - 3.458 0.514 - 880 1 2 1 0.0031 13 0 0 0 9.75E+07 4.43E+07 - - - 7.6336 0.9995 221125_WJC_METTL3_EV_vs_WT_F04.16391.16391.2 2.58E-06 20-Oct R.DTEQVDNWMSK.Q "sp|Q13813|SPTN1_HUMAN,tr|A0A0D9SF54|A0A0D9SF54_HUMAN,tr|A0A0D9SGF6|A0A0D9SGF6_HUMAN" 3 1351.5714 1.72 50101 16391 2 1351.575482 676.793 "Spectrin alpha chain, non-erythrocytic 1 OS=Homo sapiens OX=9606 GN=SPTAN1 PE=1 SV=3" 4.03 2884.7 - 452411 - - - 2.9973 - 2.079 0.566 - 460.4 1 2 0 0.0041 11 0 0 0 3.13E+06 1.82E+06 - - - 5.2001 0.9998 221125_WJC_METTL3_EV_vs_WT_F04.16392.16392.3 0.493 13/44 K.NLYSDDIPHALR.E "sp|P60228|EIF3E_HUMAN,tr|A0A7I2V3I2|A0A7I2V3I2_HUMAN,tr|A0A7I2V570|A0A7I2V570_HUMAN,tr|A0A7I2V2Q9|A0A7I2V2Q9_HUMAN,tr|H0YBP5|H0YBP5_HUMAN,tr|A0A7I2V2H9|A0A7I2V2H9_HUMAN,tr|B3KW56|B3KW56_HUMAN,tr|A0A7I2V4B4|A0A7I2V4B4_HUMAN,tr|A0A7I2V3I0|A0A7I2V3I0_HUMAN,tr|A0A7I2V3S3|A0A7I2V3S3_HUMAN,tr|A0A7I2V4G3|A0A7I2V4G3_HUMAN,tr|A0A7I2V3W9|A0A7I2V3W9_HUMAN,tr|H0YBR5|H0YBR5_HUMAN,tr|A0A7I2V429|A0A7I2V429_HUMAN,tr|A0A7I2V2W0|A0A7I2V2W0_HUMAN,tr|A0A161SXE1|A0A161SXE1_HUMAN" 16 1412.7048 1.13 50102 16392 3 1412.703412 471.9089 Eukaryotic translation initiation factor 3 subunit E OS=Homo sapiens OX=9606 GN=EIF3E PE=1 SV=1 5.21 2884.8 - 422848 - - - -1.0023 - 2.345 0.329 - 211.5 1 2 0 -0.0014 12 0 0 0 1.54E+07 1.36E+07 - - - 4.57 0.9935 221125_WJC_METTL3_EV_vs_WT_F04.16398.16398.3 0.0712 Sep-40 R.K[136.11]FLDGIYVSEK[136.11].G "sp|P32969|RL9_HUMAN,tr|H0Y9R4|H0Y9R4_HUMAN,tr|D6RAN4|D6RAN4_HUMAN,tr|H0Y9V9|H0Y9V9_HUMAN,tr|A0A2R8Y5Y7|A0A2R8Y5Y7_HUMAN" 5 1313.7202 0.83 50107 16398 3 1313.72226 438.914 60S ribosomal protein L9 OS=Homo sapiens OX=9606 GN=RPL9 PE=1 SV=1 6.07 2885.6 - 738808 - - - 1.565 - 1.623 0.216 - 102 1 2 0 0.0021 11 0 0 0 2.05E+07 2.47E+07 - - - 2.3234 1 221125_WJC_METTL3_EV_vs_WT_F04.16400.16400.2 9.21E-09 17/30 K.SPVDYGTSAGVWSQDK.W sp|Q9BYJ9|YTHD1_HUMAN 1 1695.774 2.31 50109 16400 2 1695.774796 848.8943 YTH domain-containing family protein 1 OS=Homo sapiens OX=9606 GN=YTHDF1 PE=1 SV=1 4.21 2885.9 - 1.59E+06 - - - 0.4517 - 3.377 0.631 - 1122.9 1 2 0 0.0008 16 0 0 0 8.59E+06 3.72E+06 - - - 6.6933 0.9994 221125_WJC_METTL3_EV_vs_WT_F04.16401.16401.3 0.0514 Nov-36 K.TWFDKPNFNR.T "sp|Q5T8P6|RBM26_HUMAN,tr|A0A087X0H9|A0A087X0H9_HUMAN" 2 1323.636 0.9 50110 16401 3 1323.638213 442.2193 RNA-binding protein 26 OS=Homo sapiens OX=9606 GN=RBM26 PE=1 SV=3 8.41 2885.9 - 1.27E+06 - - - 1.6568 - 1.798 0.337 - 144.5 1 2 0 0.0022 10 0 0 0 5.96E+06 6.60E+06 - - - 4.01 0.9999 221125_WJC_METTL3_EV_vs_WT_F04.16402.16402.3 4.05E-09 14/64 K.FAALDNEEEDKEEEIIK.E "sp|Q8NE71|ABCF1_HUMAN,tr|Q5STZ8|Q5STZ8_HUMAN,tr|A0A0G2JJB9|A0A0G2JJB9_HUMAN" 3 2020.9477 0.9 50111 16402 3 2020.951026 674.6565 ATP-binding cassette sub-family F member 1 OS=Homo sapiens OX=9606 GN=ABCF1 PE=1 SV=2 3.94 2886 - 1.23E+06 - - - 1.6472 - 2.981 0.554 - 216 1 2 1 0.0033 17 0 0 0 1.32E+07 1.46E+07 - - - 7.475 1 221125_WJC_METTL3_EV_vs_WT_F04.16404.16404.3 3.76E-08 14/64 K.AGVVGPELHEQLLSAEK.A "sp|Q15149|PLEC_HUMAN,tr|H0YDN1|H0YDN1_HUMAN" 2 1775.9418 4.78 50113 16404 3 1775.939877 592.9879 Plectin OS=Homo sapiens OX=9606 GN=PLEC PE=1 SV=3 4.75 2886.2 - 764736 - - - -1.0625 - 3.091 0.545 - 278.4 1 2 0 -0.0019 17 0 0 0 2.07E+07 4.33E+06 - - - 7.4666 0.9999 221125_WJC_METTL3_EV_vs_WT_F04.16408.16408.3 3.02E-05 Oct-32 R.R[166.11]DVDFELIK[136.11].V "sp|P48643|TCPE_HUMAN,tr|E9PCA1|E9PCA1_HUMAN,tr|B7ZAR1|B7ZAR1_HUMAN,tr|E7ENZ3|E7ENZ3_HUMAN" 4 1151.6305 0.001 50117 16408 3 1151.632043 384.8841 T-complex protein 1 subunit epsilon OS=Homo sapiens OX=9606 GN=CCT5 PE=1 SV=1 4.56 2886.7 - 452684 - - - 1.3016 - 1.903 0.494 - 202.8 1 2 0 0.0015 9 0 0 0 0.00E+00 3.60E+06 - - - 5.9864 1 221125_WJC_METTL3_EV_vs_WT_F04.16409.16409.3 1.34E-06 15/64 R.SAYSSYSAPVSSSLSVR.R sp|P07196|NFL_HUMAN 1 1746.8424 2.08 50118 16409 3 1746.845295 583.2881 Neurofilament light polypeptide OS=Homo sapiens OX=9606 GN=NEFL PE=1 SV=3 8.31 2886.8 - 443447 - - - 1.6321 - 2.729 0.48 - 186.4 1 2 0 0.0029 17 0 0 0 1.46E+07 7.06E+06 - - - 6.427 0.9811 221125_WJC_METTL3_EV_vs_WT_F04.16414.16414.2 0.000917 24-Aug K.NREPVQLETLSIR.G "sp|P62314|SMD1_HUMAN,tr|J3QLI9|J3QLI9_HUMAN" 2 1553.8526 4.67 50123 16414 2 1553.847434 777.9336 Small nuclear ribonucleoprotein Sm D1 OS=Homo sapiens OX=9606 GN=SNRPD1 PE=1 SV=1 6.14 2887.5 - 136128 - - - -3.2957 - 1.573 0.452 - 62.3 1 2 1 -0.0051 13 0 0 0 5.20E+06 1.11E+06 - - - 3.5405 1 221125_WJC_METTL3_EV_vs_WT_F04.16418.16418.3 6.30E-08 15/60 R.KVIGIEC[160.03]SSISDYAVK.L "sp|Q99873|ANM1_HUMAN,tr|E9PQ98|E9PQ98_HUMAN,tr|E9PKG1|E9PKG1_HUMAN,tr|E9PNR9|E9PNR9_HUMAN,tr|H0YDE4|H0YDE4_HUMAN,tr|E9PMW9|E9PMW9_HUMAN,tr|E9PIX6|E9PIX6_HUMAN" 7 1767.9077 1.82 50126 16418 3 1767.909984 590.3098 Protein arginine N-methyltransferase 1 OS=Homo sapiens OX=9606 GN=PRMT1 PE=1 SV=3 6.06 2887.8 - 2.93E+06 - - - 1.2993 - 2.93 0.631 - 283 1 2 0 0.0023 16 0 0 0 1.31E+08 7.23E+07 - - - 8.3327 1 221125_WJC_METTL3_EV_vs_WT_F04.16419.16419.3 6.08E-08 13/72 K.NLPPSGAVPVTGIPPHVVK[136.11].V "sp|Q13283|G3BP1_HUMAN,tr|A0A7I2V5M7|A0A7I2V5M7_HUMAN,tr|A0A7I2YQM1|A0A7I2YQM1_HUMAN,tr|A0A7P0P2U7|A0A7P0P2U7_HUMAN,tr|A0A7I2YQU8|A0A7I2YQU8_HUMAN,tr|A0A7I2V548|A0A7I2V548_HUMAN,tr|A0A7I2V651|A0A7I2V651_HUMAN,tr|A0A7I2V4D8|A0A7I2V4D8_HUMAN,tr|A0A7I2YQN9|A0A7I2YQN9_HUMAN" 9 1886.0869 1.38 50127 16419 3 1886.088841 629.7029 Ras GTPase-activating protein-binding protein 1 OS=Homo sapiens OX=9606 GN=G3BP1 PE=1 SV=1 8.76 2887.9 - 2.07E+06 - - - 1.0196 - 2.379 0.586 - 135.2 1 2 0 0.0019 19 0 0 0 4.21E+07 3.06E+07 - - - 7.202 1 221125_WJC_METTL3_EV_vs_WT_F04.16420.16420.3 0.000545 Dec-44 R.EHGLIFMETSAK[136.11].T "sp|P61019|RAB2A_HUMAN,sp|Q8WUD1|RAB2B_HUMAN,tr|A0A3B3ITL1|A0A3B3ITL1_HUMAN,tr|H7C125|H7C125_HUMAN" 4 1369.6791 1.08 50128 16420 3 1369.67897 457.567 Ras-related protein Rab-2A OS=Homo sapiens OX=9606 GN=RAB2A PE=1 SV=1 5.4 2887.9 - 1.69E+06 - - - -0.1219 - 2.47 0.526 - 211.9 1 2 0 -0.0002 12 0 0 0 3.32E+07 3.08E+07 - - - 6.9107 1 221125_WJC_METTL3_EV_vs_WT_F04.16421.16421.3 1.58E-07 14/56 K.VAFTGSTEVGHLIQK.A sp|P30837|AL1B1_HUMAN 1 1585.8464 1.26 50129 16421 3 1585.848355 529.6227 "Aldehyde dehydrogenase X, mitochondrial OS=Homo sapiens OX=9606 GN=ALDH1B1 PE=1 SV=3" 6.72 2888 - 1.58E+06 - - - 1.2284 - 2.871 0.559 - 160.3 1 2 0 0.0019 15 0 0 0 9.96E+06 7.91E+06 - - - 7.5238 0.9998 221125_WJC_METTL3_EV_vs_WT_F04.16422.16422.3 0.00019 Oct-52 R.LFYHIVDSDEVSTK.L sp|Q9UQE7|SMC3_HUMAN 1 1651.8094 0.75 50130 16422 3 1651.808723 551.6104 Structural maintenance of chromosomes protein 3 OS=Homo sapiens OX=9606 GN=SMC3 PE=1 SV=2 4.54 2888.1 - 1.51E+06 - - - -0.3814 - 1.844 0.409 - 60.6 1 2 0 -0.0006 14 0 0 0 1.45E+07 1.94E+07 - - - 4.726 1 221125_WJC_METTL3_EV_vs_WT_F04.16425.16425.3 3.79E-07 17/44 K.NLYSDDIPHALR[166.11].E "sp|P60228|EIF3E_HUMAN,tr|A0A7I2V3I2|A0A7I2V3I2_HUMAN,tr|A0A7I2V570|A0A7I2V570_HUMAN,tr|A0A7I2V2Q9|A0A7I2V2Q9_HUMAN,tr|H0YBP5|H0YBP5_HUMAN,tr|A0A7I2V2H9|A0A7I2V2H9_HUMAN,tr|B3KW56|B3KW56_HUMAN,tr|A0A7I2V4B4|A0A7I2V4B4_HUMAN,tr|A0A7I2V3I0|A0A7I2V3I0_HUMAN,tr|A0A7I2V3S3|A0A7I2V3S3_HUMAN,tr|A0A7I2V4G3|A0A7I2V4G3_HUMAN,tr|A0A7I2V3W9|A0A7I2V3W9_HUMAN,tr|H0YBR5|H0YBR5_HUMAN,tr|A0A7I2V429|A0A7I2V429_HUMAN,tr|A0A7I2V2W0|A0A7I2V2W0_HUMAN,tr|A0A161SXE1|A0A161SXE1_HUMAN" 16 1422.7131 1.16 50133 16425 3 1422.712852 475.245 Eukaryotic translation initiation factor 3 subunit E OS=Homo sapiens OX=9606 GN=EIF3E PE=1 SV=1 5.21 2888.4 - 825655 - - - -0.1729 - 2.425 0.545 - 457.7 1 2 0 -0.0002 12 0 0 0 1.36E+07 1.18E+07 - - - 7.0715 0.9986 221125_WJC_METTL3_EV_vs_WT_F04.16428.16428.3 0.0077 Sep-40 K.K[136.11]FEDEYSEYLK[136.11].H "sp|Q9H2H8|PPIL3_HUMAN,tr|C9K058|C9K058_HUMAN,tr|B8ZZ77|B8ZZ77_HUMAN,tr|H7BZ14|H7BZ14_HUMAN" 4 1465.6948 0.9 50136 16428 3 1465.696962 489.5722 Peptidyl-prolyl cis-trans isomerase-like 3 OS=Homo sapiens OX=9606 GN=PPIL3 PE=1 SV=1 4.41 2888.6 - 552282 - - - 1.4908 - 1.504 0.326 - 77.8 1 2 0 0.0022 11 0 0 0 3.49E+06 3.87E+06 - - - 3.3334 0.9988 221125_WJC_METTL3_EV_vs_WT_F04.16430.16430.3 0.00242 14/64 K.LYGAQFHPEVGLTENGK.V sp|P49915|GUAA_HUMAN 1 1858.9214 1.28 50138 16430 3 1858.929458 620.6477 GMP synthase [glutamine-hydrolyzing] OS=Homo sapiens OX=9606 GN=GMPS PE=1 SV=1 5.4 2888.9 - 408943 - - - 4.3547 - 2.002 0.427 - 137.4 1 2 0 0.0081 17 0 0 0 1.05E+07 8.23E+06 - - - 5.052 0.9552 221125_WJC_METTL3_EV_vs_WT_F04.16431.16431.2 0.361 26-Jul R.TVPSTTTSSNYLAK[136.11].A sp|Q6ZU65|UBN2_HUMAN 1 1476.7551 2.06 50139 16431 2 1476.750551 739.3848 Ubinuclein-2 OS=Homo sapiens OX=9606 GN=UBN2 PE=1 SV=2 8.26 2889 - 394703 - - - -3.1068 - 1.265 0.138 - 84.4 1 2 0 -0.0046 14 0 0 0 4.95E+06 2.41E+06 - - - 0.6487 1 221125_WJC_METTL3_EV_vs_WT_F04.16432.16432.2 2.60E-06 22-Dec R.EHGLIFMETSAK[136.11].T "sp|P61019|RAB2A_HUMAN,sp|Q8WUD1|RAB2B_HUMAN,tr|A0A3B3ITL1|A0A3B3ITL1_HUMAN,tr|H7C125|H7C125_HUMAN" 4 1369.6791 1.25 50140 16432 2 1369.685513 685.8468 Ras-related protein Rab-2A OS=Homo sapiens OX=9606 GN=RAB2A PE=1 SV=1 5.4 2889.2 - 304273 - - - 4.6551 - 2.676 0.598 - 626.7 1 2 0 0.0064 12 0 0 0 7.89E+06 6.33E+06 - - - 6.0457 0.9723 221125_WJC_METTL3_EV_vs_WT_F04.16433.16433.3 0.00487 Nov-36 R.TAWVFDDKYK.R "sp|P05198|IF2A_HUMAN,tr|H0YJS4|H0YJS4_HUMAN,tr|G3V4T5|G3V4T5_HUMAN" 3 1271.6186 0.98 50141 16433 3 1271.614074 424.8802 Eukaryotic translation initiation factor 2 subunit 1 OS=Homo sapiens OX=9606 GN=EIF2S1 PE=1 SV=3 5.63 2889.3 - 197408 - - - -3.5899 - 2.047 0.236 - 169.9 1 2 1 -0.0046 10 0 0 0 1.25E+07 1.27E+07 - - - 3.262 1 221125_WJC_METTL3_EV_vs_WT_F04.16437.16437.3 1.31E-07 15/64 K.FAALDNEEEDK[136.11]EEEIIK[136.11].E "sp|Q8NE71|ABCF1_HUMAN,tr|Q5STZ8|Q5STZ8_HUMAN,tr|A0A0G2JJB9|A0A0G2JJB9_HUMAN" 3 2036.9761 0.9 50143 16437 3 2036.975356 679.9993 ATP-binding cassette sub-family F member 1 OS=Homo sapiens OX=9606 GN=ABCF1 PE=1 SV=2 3.94 2889.8 - 1.80E+06 - - - -0.3638 - 3.599 0.597 - 233.7 1 2 1 -0.0007 17 0 0 0 1.32E+07 1.46E+07 - - - 8.4311 0.9996 221125_WJC_METTL3_EV_vs_WT_F04.16438.16438.2 0.000833 13/24 R.DIEVASNPAFPQR.L "sp|P42694|HELZ_HUMAN,tr|J3QS41|J3QS41_HUMAN" 2 1442.7154 2.46 50144 16438 2 1442.719584 722.365 Probable helicase with zinc finger domain OS=Homo sapiens OX=9606 GN=HELZ PE=1 SV=2 4.37 2889.9 - 1.09E+06 - - - 2.9049 - 2.744 0.525 - 528.8 1 2 0 0.0042 13 0 0 0 2.64E+07 1.07E+07 - - - 5.508 0.9999 221125_WJC_METTL3_EV_vs_WT_F04.16439.16439.3 2.85E-06 22/48 K.NREPVQLETLSIR.G "sp|P62314|SMD1_HUMAN,tr|J3QLI9|J3QLI9_HUMAN" 2 1553.8526 2.09 50145 16439 3 1553.853939 518.9581 Small nuclear ribonucleoprotein Sm D1 OS=Homo sapiens OX=9606 GN=SNRPD1 PE=1 SV=1 6.14 2890 - 7.27E+06 - - - 0.8907 - 4.031 0.505 - 1218.4 1 2 1 0.0014 13 0 0 0 9.19E+07 4.41E+07 - - - 7.9494 1 221125_WJC_METTL3_EV_vs_WT_F04.16440.16440.2 5.45E-08 19/26 K.LGKDAVEDLESVGK.G sp|P81605|DCD_HUMAN 1 1458.7566 1320.14 50146 16440 2 1458.757091 730.3856 Dermcidin OS=Homo sapiens OX=9606 GN=DCD PE=1 SV=2 4.32 2890 - 7.06E+06 - - - 0.3441 - 3.387 0.626 - 1083.8 1 2 1 0.0005 14 0 0 0 1.37E+08 1.04E+05 - - - 6.7259 1 221125_WJC_METTL3_EV_vs_WT_F04.16442.16442.2 4.49E-07 14/26 R.STSESTAALGC[160.03]LVK.D "sp|P01859|IGHG2_HUMAN,sp|P01861|IGHG4_HUMAN,tr|A0A286YFJ8|A0A286YFJ8_HUMAN,tr|A0A286YEY4|A0A286YEY4_HUMAN" 4 1422.7024 999 50148 16442 2 1422.706783 712.3585 Immunoglobulin heavy constant gamma 2 OS=Homo sapiens OX=9606 GN=IGHG2 PE=1 SV=2 5.72 2890.2 - 1.12E+06 - - - 3.0491 - 2.798 0.602 - 836.4 1 2 0 0.0043 14 0 0 0 1.10E+07 0.00E+00 - - - 6.068 1 221125_WJC_METTL3_EV_vs_WT_F04.16446.16446.2 1.82E-08 20/30 R.KVIGIEC[160.03]SSISDYAVK.L "sp|Q99873|ANM1_HUMAN,tr|E9PQ98|E9PQ98_HUMAN,tr|E9PKG1|E9PKG1_HUMAN,tr|E9PNR9|E9PNR9_HUMAN,tr|H0YDE4|H0YDE4_HUMAN,tr|E9PMW9|E9PMW9_HUMAN,tr|E9PIX6|E9PIX6_HUMAN" 7 1767.9077 1.87 50152 16446 2 1767.911962 884.9611 Protein arginine N-methyltransferase 1 OS=Homo sapiens OX=9606 GN=PRMT1 PE=1 SV=3 6.06 2890.7 - 349577 - - - 2.4181 - 3.946 0.682 - 1110.8 1 2 0 0.0043 16 0 0 0 6.63E+06 3.55E+06 - - - 7.4518 0.9964 221125_WJC_METTL3_EV_vs_WT_F04.16448.16448.2 0.196 24-Sep R.IEQISSITNQELK[136.11].M sp|Q96LB3|IFT74_HUMAN 1 1509.813 -1 50154 16448 2 1509.814937 755.9138 Intraflagellar transport protein 74 homolog OS=Homo sapiens OX=9606 GN=IFT74 PE=1 SV=1 4.53 2891 - 164809 - - - 1.2909 - 1.634 0.185 - 132.2 1 2 0 0.0019 13 0 0 0 0.00E+00 0.00E+00 - - - 1.667 0.9965 221125_WJC_METTL3_EV_vs_WT_F04.16450.16450.3 0.00127 Oct-44 K.EGNKEPILVDFK.T "sp|P18583|SON_HUMAN,tr|H7C1M2|H7C1M2_HUMAN,tr|J3QSZ5|J3QSZ5_HUMAN" 3 1387.7347 1.85 50155 16450 3 1387.731038 463.5855 Protein SON OS=Homo sapiens OX=9606 GN=SON PE=1 SV=4 4.68 2891.3 - 1.18E+06 - - - -2.6612 - 1.981 0.351 - 151.1 1 2 1 -0.0037 12 0 0 0 8.76E+06 4.75E+06 - - - 4.3471 0.9992 221125_WJC_METTL3_EV_vs_WT_F04.16452.16452.3 0.0123 13/52 R.LGVTNTIISHYDGR.Q sp|P46087|NOP2_HUMAN 1 1544.7947 1.15 50156 16452 3 1544.789226 515.9388 Probable 28S rRNA (cytosine(4447)-C(5))-methyltransferase OS=Homo sapiens OX=9606 GN=NOP2 PE=1 SV=2 6.74 2891.5 - 1.85E+06 - - - -3.5474 - 2.328 0.37 - 269.2 1 2 0 -0.0055 14 0 0 0 1.83E+07 1.58E+07 - - - 4.9093 0.9997 221125_WJC_METTL3_EV_vs_WT_F04.16453.16453.3 0.000114 16/52 R.ETLEEYNKEFAEVK.N "sp|Q13948|CASP_HUMAN,sp|P39880|CUX1_HUMAN,tr|A0A2R8Y852|A0A2R8Y852_HUMAN,tr|A0A2R8YDI1|A0A2R8YDI1_HUMAN" 4 1727.8254 1.73 50157 16453 3 1727.826233 576.9491 Protein CASP OS=Homo sapiens OX=9606 GN=CUX1 PE=1 SV=2 4.33 2891.6 - 1.66E+06 - - - 0.4838 - 2.504 0.424 - 470.8 1 2 1 0.0008 14 0 0 0 1.87E+07 1.08E+07 - - - 5.7063 0.9494 221125_WJC_METTL3_EV_vs_WT_F04.16454.16454.2 0.145 18-Aug K.DHTPSQELAL.T "sp|Q86U44|MTA70_HUMAN,tr|H0YFV6|H0YFV6_HUMAN" 2 1109.5353 - 50158 16454 2 1109.536843 555.7749 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 4.35 2891.6 - 6.13E+06 - - - 1.388 - 1.874 0.289 - 172.6 1 1 0 0.0015 10 0 0 0 - - - - - 2.9282 1 221125_WJC_METTL3_EV_vs_WT_F04.16455.16455.2 5.18E-15 20/28 K.DVDAAYMNKVELEAK.V "sp|P13647|K2C5_HUMAN,sp|O95678|K2C75_HUMAN,tr|H0YIN9|H0YIN9_HUMAN" 3 1694.8185 999 50159 16455 2 1694.818622 848.4165 "Keratin, type II cytoskeletal 5 OS=Homo sapiens OX=9606 GN=KRT5 PE=1 SV=3" 4.32 2891.7 - 1.30E+06 - - - 0.0502 - 3.927 0.747 - 1432.5 1 2 1 0.0001 15 0 0 0 1.15E+07 0.00E+00 - - - 7.9213 0.9951 221125_WJC_METTL3_EV_vs_WT_F04.16456.16456.3 0.0214 Dec-44 R.ELAVQIYEEAR[166.11]K[136.11].F "sp|O00571|DDX3X_HUMAN,sp|O15523|DDX3Y_HUMAN,tr|A0A2R8YFR4|A0A2R8YFR4_HUMAN,tr|A0A2R8YCW1|A0A2R8YCW1_HUMAN,tr|A0A2R8YDH3|A0A2R8YDH3_HUMAN,tr|A0A2R8YDT5|A0A2R8YDT5_HUMAN,tr|A0A2R8Y645|A0A2R8Y645_HUMAN,tr|A0A2R8YF78|A0A2R8YF78_HUMAN,tr|A0A0D9SFB3|A0A0D9SFB3_HUMAN,tr|A0A2R8YFS5|A0A2R8YFS5_HUMAN,tr|A0A0D9SF53|A0A0D9SF53_HUMAN,tr|A0A2R8Y5G6|A0A2R8Y5G6_HUMAN,tr|A0A2R8Y7T2|A0A2R8Y7T2_HUMAN,tr|A0A0D9SG12|A0A0D9SG12_HUMAN,tr|A0A2U3TZJ9|A0A2U3TZJ9_HUMAN,tr|A0A2R8Y4A4|A0A2R8Y4A4_HUMAN" 16 1465.7896 1.28 50160 16456 3 1465.789429 489.6038 ATP-dependent RNA helicase DDX3X OS=Homo sapiens OX=9606 GN=DDX3X PE=1 SV=3 4.79 2891.8 - 763852 - - - -0.0921 - 2.161 0.141 - 132.8 1 2 0 -0.0001 12 0 0 0 9.57E+06 7.45E+06 - - - 2.2479 0.9999 221125_WJC_METTL3_EV_vs_WT_F04.16457.16457.2 1.69E-08 14/22 R.EHGLIFMETSAK.T "sp|P61019|RAB2A_HUMAN,sp|Q8WUD1|RAB2B_HUMAN,tr|A0A3B3ITL1|A0A3B3ITL1_HUMAN,tr|H7C125|H7C125_HUMAN" 4 1361.6649 0.31 50161 16457 2 1361.663172 681.8397 Ras-related protein Rab-2A OS=Homo sapiens OX=9606 GN=RAB2A PE=1 SV=1 5.4 2891.9 - 721773 - - - -1.2962 - 2.167 0.58 - 609.6 1 2 0 -0.0018 12 0 0 0 1.02E+07 3.29E+07 - - - 5.3591 0.9879 221125_WJC_METTL3_EV_vs_WT_F04.16458.16458.3 0.0036 Sep-44 K.EGNK[136.11]EPILVDFK[136.11].T "sp|P18583|SON_HUMAN,tr|H7C1M2|H7C1M2_HUMAN,tr|J3QSZ5|J3QSZ5_HUMAN" 3 1403.7631 3.54 50162 16458 3 1403.766892 468.9283 Protein SON OS=Homo sapiens OX=9606 GN=SON PE=1 SV=4 4.68 2892 - 679872 - - - 2.6792 - 1.764 0.296 - 112.1 1 2 1 0.0038 12 0 0 0 1.87E+07 5.28E+06 - - - 3.4123 0.9999 221125_WJC_METTL3_EV_vs_WT_F04.16459.16459.2 4.22E-07 13/24 R.SNPEDQILYQTER.Y "sp|Q14165|MLEC_HUMAN,tr|F5GX14|F5GX14_HUMAN,tr|F5H1S8|F5H1S8_HUMAN" 3 1591.7478 0.95 50163 16459 2 1591.74941 796.8812 Malectin OS=Homo sapiens OX=9606 GN=MLEC PE=1 SV=1 4.14 2892.2 - 713038 - - - 1.002 - 2.431 0.593 - 644.1 1 2 0 0.0016 13 0 0 0 1.03E+07 1.08E+07 - - - 5.7003 0.9999 221125_WJC_METTL3_EV_vs_WT_F04.16461.16461.2 3.07E-06 15/24 R.SNPEDQILYQTER[166.11].Y "sp|Q14165|MLEC_HUMAN,tr|F5GX14|F5GX14_HUMAN,tr|F5H1S8|F5H1S8_HUMAN" 3 1601.7561 0.95 50165 16461 2 1601.757387 801.8853 Malectin OS=Homo sapiens OX=9606 GN=MLEC PE=1 SV=1 4.14 2892.4 - 482185 - - - 0.8129 - 2.764 0.521 - 901.5 1 2 0 0.0013 13 0 0 0 1.03E+07 1.08E+07 - - - 5.498 1 221125_WJC_METTL3_EV_vs_WT_F04.16462.16462.2 1.21E-09 16/30 K.GPGGTSDAYAVIQVGK.E sp|Q6WKZ4|RFIP1_HUMAN 1 1518.7678 1.37 50166 16462 2 1518.776137 760.3912 Rab11 family-interacting protein 1 OS=Homo sapiens OX=9606 GN=RAB11FIP1 PE=1 SV=3 5.83 2892.6 - 476069 - - - 5.4748 - 3.391 0.653 - 926.4 1 2 0 0.0083 16 0 0 0 4.73E+06 3.45E+06 - - - 6.8636 0.9964 221125_WJC_METTL3_EV_vs_WT_F04.16463.16463.3 0.0605 Sep-48 R.SNPEDQILYQTER[166.11].Y "sp|Q14165|MLEC_HUMAN,tr|F5GX14|F5GX14_HUMAN,tr|F5H1S8|F5H1S8_HUMAN" 3 1601.7561 1.24 50167 16463 3 1601.755027 534.926 Malectin OS=Homo sapiens OX=9606 GN=MLEC PE=1 SV=1 4.14 2892.7 - 406959 - - - -0.6605 - 1.643 0.229 - 89.9 1 2 0 -0.0011 13 0 0 0 5.25E+06 4.24E+06 - - - 2.4391 0.9757 221125_WJC_METTL3_EV_vs_WT_F04.16465.16465.2 0.000345 18-Sep R.TAWVFDDK[136.11]YK[136.11].R "sp|P05198|IF2A_HUMAN,tr|H0YJS4|H0YJS4_HUMAN,tr|G3V4T5|G3V4T5_HUMAN" 3 1287.647 2.66 50169 16465 2 1287.651386 644.8308 Eukaryotic translation initiation factor 2 subunit 1 OS=Homo sapiens OX=9606 GN=EIF2S1 PE=1 SV=3 5.63 2893 - 328235 - - - 3.3759 - 1.805 0.36 - 239.9 1 2 1 0.0043 10 0 0 0 6.71E+06 2.52E+06 - - - 3.347 1 221125_WJC_METTL3_EV_vs_WT_F04.16466.16466.2 9.61E-09 15/24 R.TGNFISTSTSLPR[166.11].G sp|Q9Y5J1|UTP18_HUMAN 1 1389.7128 1.29 50170 16466 2 1389.716556 695.8637 U3 small nucleolar RNA-associated protein 18 homolog OS=Homo sapiens OX=9606 GN=UTP18 PE=1 SV=3 9.41 2893.1 - 308156 - - - 2.7286 - 3.089 0.588 - 757.2 1 2 0 0.0038 13 0 0 0 1.10E+07 8.53E+06 - - - 6.2774 0.9384 221125_WJC_METTL3_EV_vs_WT_F04.16468.16468.2 1.75 22-May R.DC[160.03]GTSVPQGLLK[136.11].A sp|Q9H9A6|LRC40_HUMAN 1 1281.6478 1.91 50172 16468 2 1281.646526 641.8312 Leucine-rich repeat-containing protein 40 OS=Homo sapiens OX=9606 GN=LRRC40 PE=1 SV=1 5.83 2893.3 - 239914 - - - -1.0229 - 1.222 0.062 - 70.4 12 2 0 -0.0013 12 0 0 0 3.72E+06 1.95E+06 - - - -0.456 1 221125_WJC_METTL3_EV_vs_WT_F04.16471.16471.3 5.99E-05 14/72 K.NLPPSGAVPVTGIPPHVVK.V "sp|Q13283|G3BP1_HUMAN,tr|A0A7I2V5M7|A0A7I2V5M7_HUMAN,tr|A0A7I2YQM1|A0A7I2YQM1_HUMAN,tr|A0A7P0P2U7|A0A7P0P2U7_HUMAN,tr|A0A7I2YQU8|A0A7I2YQU8_HUMAN,tr|A0A7I2V548|A0A7I2V548_HUMAN,tr|A0A7I2V651|A0A7I2V651_HUMAN,tr|A0A7I2V4D8|A0A7I2V4D8_HUMAN,tr|A0A7I2YQN9|A0A7I2YQN9_HUMAN" 9 1878.0727 1.38 50174 16471 3 1878.075168 627.0315 Ras GTPase-activating protein-binding protein 1 OS=Homo sapiens OX=9606 GN=G3BP1 PE=1 SV=1 8.76 2893.7 - 2.87E+06 - - - 1.3045 - 2.26 0.513 - 128.2 1 2 0 0.0024 19 0 0 0 4.21E+07 3.06E+07 - - - 6.262 0.9998 221125_WJC_METTL3_EV_vs_WT_F04.16474.16474.3 1.37E-05 14/52 R.TVTEIDEK[136.11]EYISLR[166.11].L "sp|P61289|PSME3_HUMAN,tr|B3KQ25|B3KQ25_HUMAN,tr|K7ESG5|K7ESG5_HUMAN,tr|K9J957|K9J957_HUMAN,tr|A0A087WTV2|A0A087WTV2_HUMAN" 5 1712.8952 0.08 50176 16474 3 1712.895321 571.9723 Proteasome activator complex subunit 3 OS=Homo sapiens OX=9606 GN=PSME3 PE=1 SV=1 4.41 2894 - 1.72E+06 - - - 0.0992 - 2.867 0.435 - 173.6 1 2 1 0.0002 14 0 0 0 1.18E+06 1.43E+07 - - - 6.1889 0.9995 221125_WJC_METTL3_EV_vs_WT_F04.16475.16475.3 0.00862 Oct-48 K.ASLASLPPLHVAK.L "sp|Q14203|DCTN1_HUMAN,tr|A0A804CDA6|A0A804CDA6_HUMAN,tr|E7EX90|E7EX90_HUMAN,tr|A0A7P0Z4C3|A0A7P0Z4C3_HUMAN,tr|E7EWF7|E7EWF7_HUMAN" 5 1302.766 1.78 50177 16475 3 1302.765429 435.2626 Dynactin subunit 1 OS=Homo sapiens OX=9606 GN=DCTN1 PE=1 SV=3 8.8 2894 - 2.77E+06 - - - -0.4168 - 1.889 0.322 - 140.1 1 2 0 -0.0005 13 0 0 0 6.04E+07 3.39E+07 - - - 3.8543 0.9998 221125_WJC_METTL3_EV_vs_WT_F04.16477.16477.3 0.0466 14/44 R.ELAVQIYEEARK.F "sp|O00571|DDX3X_HUMAN,sp|O15523|DDX3Y_HUMAN,tr|A0A2R8YFR4|A0A2R8YFR4_HUMAN,tr|A0A2R8YCW1|A0A2R8YCW1_HUMAN,tr|A0A2R8YDH3|A0A2R8YDH3_HUMAN,tr|A0A2R8YDT5|A0A2R8YDT5_HUMAN,tr|A0A2R8Y645|A0A2R8Y645_HUMAN,tr|A0A2R8YF78|A0A2R8YF78_HUMAN,tr|A0A0D9SFB3|A0A0D9SFB3_HUMAN,tr|A0A2R8YFS5|A0A2R8YFS5_HUMAN,tr|A0A0D9SF53|A0A0D9SF53_HUMAN,tr|A0A2R8Y5G6|A0A2R8Y5G6_HUMAN,tr|A0A2R8Y7T2|A0A2R8Y7T2_HUMAN,tr|A0A0D9SG12|A0A0D9SG12_HUMAN,tr|A0A2U3TZJ9|A0A2U3TZJ9_HUMAN,tr|A0A2R8Y4A4|A0A2R8Y4A4_HUMAN" 16 1447.7671 1.26 50179 16477 3 1447.768954 483.5963 ATP-dependent RNA helicase DDX3X OS=Homo sapiens OX=9606 GN=DDX3X PE=1 SV=3 4.79 2894.2 - 1.25E+06 - - - 1.2847 - 2.319 0.335 - 305.7 1 2 0 0.0019 12 0 0 0 9.51E+06 7.52E+06 - - - 4.6059 1 221125_WJC_METTL3_EV_vs_WT_F04.16478.16478.3 6.39E-07 24/60 R.LGGAIAAINSIQHNTR.S "sp|Q68CQ7|GL8D1_HUMAN,tr|C9J880|C9J880_HUMAN" 2 1634.8853 1.1 50180 16478 3 1634.885966 545.969 Glycosyltransferase 8 domain-containing protein 1 OS=Homo sapiens OX=9606 GN=GLT8D1 PE=1 SV=2 9.76 2894.3 - 1.20E+06 - - - 0.4367 - 4.495 0.558 - 1245 1 2 0 0.0007 16 0 0 0 1.24E+07 1.13E+07 - - - 8.6174 0.946 221125_WJC_METTL3_EV_vs_WT_F04.16479.16479.2 0.737 16-Jun K.EGENIC[160.03]FEK.- tr|F2Z2A5|F2Z2A5_HUMAN 1 1124.4808 3.14 50181 16479 2 1124.478981 563.2477 DNA topoisomerase OS=Homo sapiens OX=9606 GN=TOP3B PE=1 SV=1 4.25 2894.4 - 1.12E+06 - - - -1.6399 - 1.1 0.071 - 99.4 1 2 0 -0.0018 9 0 0 0 1.47E+07 4.68E+06 - - - -0.1594 0.9999 221125_WJC_METTL3_EV_vs_WT_F04.16480.16480.2 0.0014 14/24 R.DIEVASNPAFPQR[166.11].L "sp|P42694|HELZ_HUMAN,tr|J3QS41|J3QS41_HUMAN" 2 1452.7237 2.55 50182 16480 2 1452.725588 727.3691 Probable helicase with zinc finger domain OS=Homo sapiens OX=9606 GN=HELZ PE=1 SV=2 4.37 2894.6 - 795827 - - - 1.3251 - 2.782 0.496 - 762.9 1 2 0 0.0019 13 0 0 0 2.52E+07 9.89E+06 - - - 5.3298 1 221125_WJC_METTL3_EV_vs_WT_F04.16481.16481.2 1.65E-05 19/24 L.GKDAVEDLESVGK.G sp|P81605|DCD_HUMAN 1 1345.6725 999 50183 16481 2 1345.673386 673.8435 Dermcidin OS=Homo sapiens OX=9606 GN=DCD PE=1 SV=2 4.32 2894.7 - 637011 - - - 0.6398 - 3.237 0.551 - 928.3 1 1 1 0.0009 13 0 0 0 6.92E+06 0.00E+00 - - - 6.1252 0.9998 221125_WJC_METTL3_EV_vs_WT_F04.16483.16483.3 7.58E-06 15/44 R.LLRDYQELMNTK.L sp|P04264|K2C1_HUMAN 1 1522.7814 3.65 50185 16483 3 1522.780953 508.6011 "Keratin, type II cytoskeletal 1 OS=Homo sapiens OX=9606 GN=KRT1 PE=1 SV=6" 6.07 2895 - 550224 - - - -0.2699 - 2.669 0.447 - 406.6 1 2 1 -0.0004 12 0 0 0 1.17E+08 3.21E+07 - - - 6.2446 0.9999 221125_WJC_METTL3_EV_vs_WT_F04.16484.16484.3 2.74E-05 Sep-36 K.KDVLETFTVK.S "sp|P21926|CD9_HUMAN,tr|A6NNI4|A6NNI4_HUMAN,tr|A0A2R8Y478|A0A2R8Y478_HUMAN,tr|A0A7I2V3T7|A0A7I2V3T7_HUMAN,tr|G8JLH6|G8JLH6_HUMAN,tr|A0A7I2V3T0|A0A7I2V3T0_HUMAN,tr|F5GXT1|F5GXT1_HUMAN,tr|A0A087WU13|A0A087WU13_HUMAN" 8 1178.6547 1.05 50186 16484 3 1178.653943 393.8922 CD9 antigen OS=Homo sapiens OX=9606 GN=CD9 PE=1 SV=4 6.07 2895.1 - 441687 - - - -0.6338 - 2.072 0.451 - 137.9 1 2 0 -0.0007 10 0 0 0 3.42E+06 3.24E+06 - - - 5.6956 0.9999 221125_WJC_METTL3_EV_vs_WT_F04.16490.16490.3 0.00521 14/48 K.ASLASLPPLHVAK[136.11].L "sp|Q14203|DCTN1_HUMAN,tr|A0A804CDA6|A0A804CDA6_HUMAN,tr|E7EX90|E7EX90_HUMAN,tr|A0A7P0Z4C3|A0A7P0Z4C3_HUMAN,tr|E7EWF7|E7EWF7_HUMAN" 5 1310.7802 1.83 50190 16490 3 1310.77991 437.934 Dynactin subunit 1 OS=Homo sapiens OX=9606 GN=DCTN1 PE=1 SV=3 8.8 2895.9 - 3.93E+06 - - - -0.1999 - 2.238 0.386 - 340.6 1 2 0 -0.0003 13 0 0 0 7.33E+07 4.02E+07 - - - 5.0276 0.9994 221125_WJC_METTL3_EV_vs_WT_F04.16491.16491.4 0.00573 14/90 R.ALVVEMSRPRPLNTWK.L "sp|Q96PK6|RBM14_HUMAN,tr|B8ZZ74|B8ZZ74_HUMAN,tr|F8WDX3|F8WDX3_HUMAN,tr|A0A0A0MSL8|A0A0A0MSL8_HUMAN,tr|A0A0A6YYI9|A0A0A6YYI9_HUMAN" 5 1896.0404 1.64 50191 16491 4 1896.041152 475.0174 RNA-binding protein 14 OS=Homo sapiens OX=9606 GN=RBM14 PE=1 SV=2 10.84 2895.9 - 1.69E+06 - - - 0.4114 - 2.352 0.313 - 135.2 1 2 0 0.0008 16 0 0 0 3.60E+07 2.20E+07 - - - 2.2514 0.8008 221125_WJC_METTL3_EV_vs_WT_F04.16493.16493.3 0.143 14/40 Q.KFAAQELIEVK[136.11].R "sp|Q86U44|MTA70_HUMAN,tr|F5H6D8|F5H6D8_HUMAN,tr|H0YFV6|H0YFV6_HUMAN,tr|B4DTN4|B4DTN4_HUMAN" 4 1282.7376 - 50193 16493 3 1282.737732 428.5865 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 6.14 2896.1 - 1.67E+06 - - - 0.0733 - 2.667 0.125 - 456.7 1 1 0 0.0001 11 0 0 0 - - - - - 2.7203 0.9942 221125_WJC_METTL3_EV_vs_WT_F04.16498.16498.2 1.33E-06 14/20 Q.K[136.11]FAAQELIEVK[136.11].R "sp|Q86U44|MTA70_HUMAN,tr|F5H6D8|F5H6D8_HUMAN,tr|H0YFV6|H0YFV6_HUMAN,tr|B4DTN4|B4DTN4_HUMAN" 4 1290.7518 0.001 50198 16498 2 1290.750612 646.3832 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 6.14 2896.5 - 918113 - - - -0.9498 - 2.842 0.519 - 486 1 1 0 -0.0012 11 0 0 0 0.00E+00 9.21E+06 - - - 5.6996 0.9997 221125_WJC_METTL3_EV_vs_WT_F04.16499.16499.3 1.9 14/36 R.K[136.11]YEAIQLTFK[136.11].Q sp|Q9UQE7|SMC3_HUMAN 1 1255.7147 1.83 50199 16499 3 1255.714788 419.5789 Structural maintenance of chromosomes protein 3 OS=Homo sapiens OX=9606 GN=SMC3 PE=1 SV=2 8.5 2896.7 - 705529 - - - 0.051 - 2.508 0.282 - 395.9 1 2 0 0.0001 10 0 0 0 1.85E+07 1.01E+07 - - - 4.3693 0.9999 221125_WJC_METTL3_EV_vs_WT_F04.16500.16500.3 6.14E-05 Dec-48 R.SNPEDQILYQTER.Y "sp|Q14165|MLEC_HUMAN,tr|F5GX14|F5GX14_HUMAN,tr|F5H1S8|F5H1S8_HUMAN" 3 1591.7478 1.24 50200 16500 3 1591.751162 531.5899 Malectin OS=Homo sapiens OX=9606 GN=MLEC PE=1 SV=1 4.14 2896.8 - 678638 - - - 2.1027 - 2.251 0.435 - 243.7 1 2 0 0.0033 13 0 0 0 5.25E+06 4.24E+06 - - - 5.5888 0.9999 221125_WJC_METTL3_EV_vs_WT_F04.16501.16501.2 0.000319 22-Oct K.GSSESPFDLTTK[136.11].R "sp|Q03112|MECOM_HUMAN,tr|H9KVD4|H9KVD4_HUMAN,tr|E7EUL6|E7EUL6_HUMAN,tr|A0A0C3SFZ7|A0A0C3SFZ7_HUMAN" 4 1275.6074 1.48 50201 16501 2 1275.607558 638.811 Histone-lysine N-methyltransferase MECOM OS=Homo sapiens OX=9606 GN=MECOM PE=1 SV=3 4.37 2896.9 - 628306 - - - 0.1145 - 2.195 0.478 - 414.4 1 2 0 0.0001 12 0 0 0 1.00E+07 6.78E+06 - - - 4.64 1 221125_WJC_METTL3_EV_vs_WT_F04.16502.16502.2 7.41E-09 13/28 R.IQFDEGYDNYPGQEK.T sp|Q92665|RT31_HUMAN 1 1801.7795 1.5 50202 16502 2 1801.781098 901.897 "28S ribosomal protein S31, mitochondrial OS=Homo sapiens OX=9606 GN=MRPS31 PE=1 SV=3" 3.92 2897 - 585796 - - - 0.8819 - 2.633 0.667 - 333 1 2 0 0.0016 15 0 0 0 5.43E+06 3.62E+06 - - - 6.3471 0.9998 221125_WJC_METTL3_EV_vs_WT_F04.16503.16503.2 1.30E-05 26-Nov K.NGIAGSSLPPPPIK.H sp|Q9Y5A9|YTHD2_HUMAN 1 1346.7558 1.8 50203 16503 2 1346.75442 674.3852 YTH domain-containing family protein 2 OS=Homo sapiens OX=9606 GN=YTHDF2 PE=1 SV=2 8.75 2897.2 - 532560 - - - -1.0254 - 2.07 0.465 - 230.2 1 2 0 -0.0014 14 0 0 0 7.45E+06 4.13E+06 - - - 4.3008 0.9998 221125_WJC_METTL3_EV_vs_WT_F04.16504.16504.2 2.22E-07 28-Dec K.TPPGVSAPTEPLLC[160.03]K.F "sp|P29558|RBMS1_HUMAN,tr|E7ETU5|E7ETU5_HUMAN,tr|F6Y5H0|F6Y5H0_HUMAN" 3 1565.8123 4.43 50204 16504 2 1565.808778 783.9134 "RNA-binding motif, single-stranded-interacting protein 1 OS=Homo sapiens OX=9606 GN=RBMS1 PE=1 SV=3" 5.66 2897.3 - 389811 - - - -2.2685 - 2.321 0.589 - 310 1 2 0 -0.0036 15 0 0 0 3.63E+06 8.20E+05 - - - 5.4603 1 221125_WJC_METTL3_EV_vs_WT_F04.16505.16505.2 3.77E-08 13/28 R.IQFDEGYDNYPGQEK[136.11].T sp|Q92665|RT31_HUMAN 1 1809.7937 1.57 50205 16505 2 1809.792016 905.9041 "28S ribosomal protein S31, mitochondrial OS=Homo sapiens OX=9606 GN=MRPS31 PE=1 SV=3" 3.92 2897.4 - 332202 - - - -0.9355 - 2.63 0.656 - 343.5 1 2 0 -0.0017 15 0 0 0 7.81E+06 4.96E+06 - - - 6.2631 0.9994 221125_WJC_METTL3_EV_vs_WT_F04.16507.16507.3 0.00447 Sep-36 R.K[136.11]IEFPLPDEK[136.11].T sp|P62191|PRS4_HUMAN 1 1230.6831 0.7 50207 16507 3 1230.6842 411.235 26S proteasome regulatory subunit 4 OS=Homo sapiens OX=9606 GN=PSMC1 PE=1 SV=1 4.68 2897.7 - 272809 - - - 0.9019 - 1.858 0.304 - 116.3 1 2 0 0.0011 10 0 0 0 1.89E+06 2.69E+06 - - - 3.7382 1 221125_WJC_METTL3_EV_vs_WT_F04.16515.16515.2 4.04E-06 16/28 K.EGGQIAVFDATNTTR.E "sp|Q16875|F263_HUMAN,tr|A0A1W2PR17|A0A1W2PR17_HUMAN,tr|Q5W015|Q5W015_HUMAN,tr|A0A1W2PNV9|A0A1W2PNV9_HUMAN,tr|F2Z2I2|F2Z2I2_HUMAN,tr|Q5VX20|Q5VX20_HUMAN" 6 1578.7638 3.35 50213 16515 2 1578.763987 790.3892 "6-phosphofructo-2-kinase\fructose-2,6-bisphosphatase 3 OS=Homo sapiens OX=9606 GN=PFKFB3 PE=1 SV=1" 4.37 2898.4 - 1.61E+06 - - - 0.1191 - 2.683 0.596 - 853.7 1 2 0 0.0002 15 0 0 0 9.64E+07 2.87E+07 - - - 5.8694 0.9999 221125_WJC_METTL3_EV_vs_WT_F04.16516.16516.3 2.79E-07 13/52 K.FEDPKFEVIEKPQA.- sp|P18859|ATP5J_HUMAN 1 1675.8457 2.06 50214 16516 3 1675.848672 559.6225 "ATP synthase-coupling factor 6, mitochondrial OS=Homo sapiens OX=9606 GN=ATP5PF PE=1 SV=1" 4.41 2898.5 - 1.59E+06 - - - 1.7508 - 2.736 0.588 - 115.3 1 2 1 0.0029 14 0 0 0 3.38E+07 1.64E+07 - - - 7.7696 1 221125_WJC_METTL3_EV_vs_WT_F04.16517.16517.2 1.92E-09 20-Dec K.NQFETEINITK.T sp|P15924|DESP_HUMAN 1 1335.667 13.24 50215 16517 2 1335.667544 668.8408 Desmoplakin OS=Homo sapiens OX=9606 GN=DSP PE=1 SV=3 4.53 2898.6 - 1.43E+06 - - - 0.3736 - 2.659 0.614 - 593.1 1 2 0 0.0005 11 0 0 0 3.07E+07 2.32E+06 - - - 6.2214 0.9999 221125_WJC_METTL3_EV_vs_WT_F04.16518.16518.3 0.000227 14/60 R.ALVVEMSRPRPLNTWK.L "sp|Q96PK6|RBM14_HUMAN,tr|B8ZZ74|B8ZZ74_HUMAN,tr|F8WDX3|F8WDX3_HUMAN,tr|A0A0A0MSL8|A0A0A0MSL8_HUMAN,tr|A0A0A6YYI9|A0A0A6YYI9_HUMAN" 5 1896.0404 1.54 50216 16518 3 1896.040481 633.0207 RNA-binding protein 14 OS=Homo sapiens OX=9606 GN=RBM14 PE=1 SV=2 10.84 2898.7 - 1.32E+06 - - - 0.0575 - 2.506 0.377 - 253.4 1 2 0 0.0001 16 0 0 0 8.26E+06 5.37E+06 - - - 5.1004 0.9999 221125_WJC_METTL3_EV_vs_WT_F04.16519.16519.3 4.71E-05 Nov-36 R.KYEAIQLTFK.Q sp|Q9UQE7|SMC3_HUMAN 1 1239.6863 0.93 50217 16519 3 1239.686279 414.2361 Structural maintenance of chromosomes protein 3 OS=Homo sapiens OX=9606 GN=SMC3 PE=1 SV=2 8.5 2898.8 - 1.24E+06 - - - -0.0363 - 2.153 0.38 - 199.5 1 2 0 0 10 0 0 0 8.27E+06 8.86E+06 - - - 5.0162 0.9999 221125_WJC_METTL3_EV_vs_WT_F04.16521.16521.3 0.0117 19/60 R.ALVVEMSR[166.11]PR[166.11]PLNTWK[136.11].L "sp|Q96PK6|RBM14_HUMAN,tr|B8ZZ74|B8ZZ74_HUMAN,tr|F8WDX3|F8WDX3_HUMAN,tr|A0A0A0MSL8|A0A0A0MSL8_HUMAN,tr|A0A0A6YYI9|A0A0A6YYI9_HUMAN" 5 1924.0711 2.05 50219 16521 3 1924.072104 642.3643 RNA-binding protein 14 OS=Homo sapiens OX=9606 GN=RBM14 PE=1 SV=2 10.84 2899 - 856661 - - - 0.5156 - 2.896 0.33 - 432.9 1 2 0 0.001 16 0 0 0 1.59E+07 7.80E+06 - - - 4.9473 0.998 221125_WJC_METTL3_EV_vs_WT_F04.16523.16523.2 0.0304 22-Dec R.LLRDYQELMNTK.L sp|P04264|K2C1_HUMAN 1 1522.7814 6.64 50221 16523 2 1522.781022 762.398 "Keratin, type II cytoskeletal 1 OS=Homo sapiens OX=9606 GN=KRT1 PE=1 SV=6" 6.07 2899.3 - 754367 - - - -0.2246 - 2.53 0.368 - 475.9 1 2 1 -0.0003 12 0 0 0 1.72E+07 2.59E+06 - - - 4.2012 0.9999 221125_WJC_METTL3_EV_vs_WT_F04.16525.16525.3 2.26E-05 Oct-56 R.IQFDEGYDNYPGQEK.T sp|Q92665|RT31_HUMAN 1 1801.7795 2.93 50223 16525 3 1801.778241 601.6004 "28S ribosomal protein S31, mitochondrial OS=Homo sapiens OX=9606 GN=MRPS31 PE=1 SV=3" 3.92 2899.5 - 604068 - - - -0.7037 - 1.854 0.498 - 72.2 1 2 0 -0.0013 15 0 0 0 7.94E+06 2.71E+06 - - - 5.7027 1 221125_WJC_METTL3_EV_vs_WT_F04.16526.16526.2 1.23E-09 17/28 K.EGGQIAVFDATNTTR[166.11].E "sp|Q16875|F263_HUMAN,tr|A0A1W2PR17|A0A1W2PR17_HUMAN,tr|Q5W015|Q5W015_HUMAN,tr|A0A1W2PNV9|A0A1W2PNV9_HUMAN,tr|F2Z2I2|F2Z2I2_HUMAN,tr|Q5VX20|Q5VX20_HUMAN" 6 1588.7721 3.35 50224 16526 2 1588.774694 795.3933 "6-phosphofructo-2-kinase\fructose-2,6-bisphosphatase 3 OS=Homo sapiens OX=9606 GN=PFKFB3 PE=1 SV=1" 4.37 2899.6 - 593535 - - - 1.6522 - 2.975 0.546 - 932.9 1 2 0 0.0026 15 0 0 0 9.64E+07 2.87E+07 - - - 5.7533 0.9999 221125_WJC_METTL3_EV_vs_WT_F04.16527.16527.2 3.51E-07 13/24 R.TTPSYVAFTDTER[166.11].L "sp|P48741|HSP77_HUMAN,sp|P54652|HSP72_HUMAN,sp|P0DMV8|HS71A_HUMAN,sp|P34931|HS71L_HUMAN,sp|P11142|HSP7C_HUMAN,sp|P0DMV9|HS71B_HUMAN,sp|P17066|HSP76_HUMAN,tr|E9PQQ4|E9PQQ4_HUMAN,tr|E9PNE6|E9PNE6_HUMAN,tr|E9PKE3|E9PKE3_HUMAN,tr|E9PLF4|E9PLF4_HUMAN,tr|Q53FA3|Q53FA3_HUMAN,tr|E9PI65|E9PI65_HUMAN,tr|E9PK54|E9PK54_HUMAN,tr|E9PN25|E9PN25_HUMAN,tr|E9PPY6|E9PPY6_HUMAN,tr|E9PQK7|E9PQK7_HUMAN,tr|A0A0G2JIW1|A0A0G2JIW1_HUMAN" 18 1496.7023 0.001 50225 16527 2 1496.700909 749.3584 Putative heat shock 70 kDa protein 7 OS=Homo sapiens OX=9606 GN=HSPA7 PE=5 SV=2 4.37 2899.8 - 575541 - - - -0.902 - 2.395 0.544 - 498.5 1 2 0 -0.0014 13 0 0 0 0.00E+00 1.69E+06 - - - 5.3001 1 221125_WJC_METTL3_EV_vs_WT_F04.16530.16530.2 1.20E-08 13/26 R.ELGSEC[160.03]GIEFDEEK.T "sp|P39656|OST48_HUMAN,tr|U3KQ84|U3KQ84_HUMAN,tr|A0A0C4DGS1|A0A0C4DGS1_HUMAN" 3 1640.6876 0.92 50228 16530 2 1640.685067 821.3511 Dolichyl-diphosphooligosaccharide--protein glycosyltransferase 48 kDa subunit OS=Homo sapiens OX=9606 GN=DDOST PE=1 SV=4 3.83 2900.2 - 304171 - - - -1.5335 - 2.613 0.688 - 527.7 1 2 0 -0.0025 14 0 0 0 2.06E+06 2.25E+06 - - - 6.5321 0.9999 221125_WJC_METTL3_EV_vs_WT_F04.16532.16532.2 1.96E-05 13/24 R.TGNFISTSTSLPR.G sp|Q9Y5J1|UTP18_HUMAN 1 1379.7045 1.29 50229 16532 2 1379.703817 690.8595 U3 small nucleolar RNA-associated protein 18 homolog OS=Homo sapiens OX=9606 GN=UTP18 PE=1 SV=3 9.41 2900.5 - 285600 - - - -0.4907 - 2.418 0.52 - 580.1 1 2 0 -0.0007 13 0 0 0 1.10E+07 8.53E+06 - - - 5.1476 1 221125_WJC_METTL3_EV_vs_WT_F04.16533.16533.2 5.83E-07 13/18 R.HFDQFWSAAK.T "sp|P49750|YLPM1_HUMAN,tr|H0YIQ2|H0YIQ2_HUMAN,tr|F8VU51|F8VU51_HUMAN,tr|H0YI23|H0YI23_HUMAN" 4 1235.5724 1.64 50230 16533 2 1235.574858 618.7935 YLP motif-containing protein 1 OS=Homo sapiens OX=9606 GN=YLPM1 PE=1 SV=4 6.74 2900.7 - 450377 - - - 2.0242 - 2.471 0.579 - 475 1 2 0 0.0025 10 0 0 0 5.97E+06 3.64E+06 - - - 5.8418 1 221125_WJC_METTL3_EV_vs_WT_F04.16534.16534.3 6.79E-05 14/52 R.SEVTFLAPVTRPDK.V "sp|Q96GK7|FAH2A_HUMAN,tr|C9JGM0|C9JGM0_HUMAN" 2 1558.8355 1.08 50231 16534 3 1558.836947 520.6191 Fumarylacetoacetate hydrolase domain-containing protein 2A OS=Homo sapiens OX=9606 GN=FAHD2A PE=1 SV=1 5.79 2900.7 - 1.99E+06 - - - 0.9231 - 2.413 0.465 - 271 1 2 0 0.0014 14 0 0 0 2.83E+07 2.63E+07 - - - 6.0648 0.9996 221125_WJC_METTL3_EV_vs_WT_F04.16535.16535.4 0.00034 14/90 R.LLIYKVSNRFSGVPDR.F sp|A0A075B6R9|KVD24_HUMAN 1 1863.0367 999 50232 16535 4 1863.039891 466.7664 Probable non-functional immunoglobulin kappa variable 2D-24 OS=Homo sapiens OX=9606 GN=IGKV2D-24 PE=1 SV=1 9.99 2900.8 - 1.60E+06 - - - 1.7305 - 2.527 0.444 - 138.7 1 2 2 0.0032 16 0 0 0 5.76E+07 0.00E+00 - - - 3.4162 0.9988 221125_WJC_METTL3_EV_vs_WT_F04.16536.16536.3 0.009 Aug-40 R.VQIEHISSLIK[136.11].L sp|O00231|PSD11_HUMAN 1 1273.7485 0.69 50233 16536 3 1273.749463 425.5901 26S proteasome non-ATPase regulatory subunit 11 OS=Homo sapiens OX=9606 GN=PSMD11 PE=1 SV=3 6.72 2900.9 - 1.52E+06 - - - 0.727 - 1.88 0.254 - 102.5 1 2 0 0.0009 11 0 0 0 9.08E+06 1.32E+07 - - - 3.1649 1 221125_WJC_METTL3_EV_vs_WT_F04.16538.16538.2 3.14E-05 13/24 R.DSLENTLTESEAR.Y "sp|Q15323|K1H1_HUMAN,sp|Q14532|K1H2_HUMAN,sp|O76009|KT33A_HUMAN,tr|A0A140TA69|A0A140TA69_HUMAN" 4 1463.674 2.72 50235 16538 2 1463.673353 732.8443 "Keratin, type I cuticular Ha1 OS=Homo sapiens OX=9606 GN=KRT31 PE=1 SV=3" 4 2901.1 - 778790 - - - -0.4291 - 2.888 0.554 - 778 1 2 0 -0.0006 13 0 0 0 9.62E+06 3.54E+06 - - - 5.8546 0.9999 221125_WJC_METTL3_EV_vs_WT_F04.16539.16539.3 2.20E-05 Nov-40 R.VQIEHISSLIK.L sp|O00231|PSD11_HUMAN 1 1265.7343 0.69 50236 16539 3 1265.736392 422.9187 26S proteasome non-ATPase regulatory subunit 11 OS=Homo sapiens OX=9606 GN=PSMD11 PE=1 SV=3 6.72 2901.3 - 776610 - - - 1.6236 - 2.281 0.429 - 229.5 1 2 0 0.0021 11 0 0 0 9.08E+06 1.32E+07 - - - 5.6649 1 221125_WJC_METTL3_EV_vs_WT_F04.16540.16540.2 2.29E-06 13/24 K.TSQLGDSPFYPGK.T sp|P49790|NU153_HUMAN 1 1395.667 1.62 50237 16540 2 1395.667655 698.8408 Nuclear pore complex protein Nup153 OS=Homo sapiens OX=9606 GN=NUP153 PE=1 SV=2 5.5 2901.4 - 653677 - - - 0.4371 - 2.683 0.571 - 415 1 2 0 0.0006 13 0 0 0 1.92E+08 1.19E+08 - - - 5.7912 1 221125_WJC_METTL3_EV_vs_WT_F04.16541.16541.2 0.000446 15/32 F.QADVSLGNDAAVPLSGR.G "sp|O43251|RFOX2_HUMAN,tr|B0QYV1|B0QYV1_HUMAN,tr|B0QYY4|B0QYY4_HUMAN,tr|S4R469|S4R469_HUMAN,tr|A0A0G2JRD1|A0A0G2JRD1_HUMAN,tr|A0A0G2JRA5|A0A0G2JRA5_HUMAN,tr|S4R3K7|S4R3K7_HUMAN" 7 1668.8431 1.97 50238 16541 2 1668.844868 835.4288 RNA binding protein fox-1 homolog 2 OS=Homo sapiens OX=9606 GN=RBFOX2 PE=1 SV=3 4.21 2901.5 - 542486 - - - 1.0522 - 3.389 0.63 - 502.5 1 1 0 0.0018 17 0 0 0 3.79E+06 1.93E+06 - - - 6.6944 0.9993 221125_WJC_METTL3_EV_vs_WT_F04.16542.16542.3 0.0512 Oct-56 R.IQFDEGYDNYPGQEK[136.11].T sp|Q92665|RT31_HUMAN 1 1809.7937 2.02 50239 16542 3 1809.790111 604.2718 "28S ribosomal protein S31, mitochondrial OS=Homo sapiens OX=9606 GN=MRPS31 PE=1 SV=3" 3.92 2901.7 - 452444 - - - -1.9881 - 1.788 0.353 - 68.9 1 2 0 -0.0036 15 0 0 0 3.82E+06 1.89E+06 - - - 3.9909 0.9898 221125_WJC_METTL3_EV_vs_WT_F04.16543.16543.2 0.0029 18-Sep R.QWEESWQQVK.Q "sp|Q9H9P5|UNKL_HUMAN,tr|A0A0A0MRZ1|A0A0A0MRZ1_HUMAN,tr|A0A0A0MSC7|A0A0A0MSC7_HUMAN,tr|E9PDK2|E9PDK2_HUMAN" 4 1346.6255 8.88 50240 16543 2 1346.625148 674.32 Putative E3 ubiquitin-protein ligase UNKL OS=Homo sapiens OX=9606 GN=UNKL PE=1 SV=3 4.53 2901.8 - 395984 - - - -0.2725 - 1.405 0.101 - 202.6 2 2 0 -0.0004 10 0 0 0 6.02E+06 6.78E+05 - - - 0.6015 1 221125_WJC_METTL3_EV_vs_WT_F04.16545.16545.2 2.99E-07 26-Dec R.ELGSEC[160.03]GIEFDEEK[136.11].T "sp|P39656|OST48_HUMAN,tr|U3KQ84|U3KQ84_HUMAN,tr|A0A0C4DGS1|A0A0C4DGS1_HUMAN" 3 1648.7018 0.92 50242 16545 2 1648.704636 825.3582 Dolichyl-diphosphooligosaccharide--protein glycosyltransferase 48 kDa subunit OS=Homo sapiens OX=9606 GN=DDOST PE=1 SV=4 3.83 2902.1 - 374880 - - - 1.7305 - 2.535 0.714 - 485.4 1 2 0 0.0029 14 0 0 0 2.06E+06 2.25E+06 - - - 6.648 0.9938 221125_WJC_METTL3_EV_vs_WT_F04.16546.16546.3 0.414 Sep-64 K.AASDIAMTELPPTHPIR.L "sp|P62258|1433E_HUMAN,tr|K7EM20|K7EM20_HUMAN" 2 1818.9298 1.59 50243 16546 3 1818.932198 607.3172 14-3-3 protein epsilon OS=Homo sapiens OX=9606 GN=YWHAE PE=1 SV=1 5.32 2902.2 - 374215 - - - 1.3079 - 2.205 0.167 - 92.4 2 2 0 0.0024 17 0 0 0 6.28E+06 3.96E+06 - - - 2.2595 1 221125_WJC_METTL3_EV_vs_WT_F04.16549.16549.2 6.74E-11 15/32 F.QADVSLGNDAAVPLSGR[166.11].G "sp|O43251|RFOX2_HUMAN,tr|B0QYV1|B0QYV1_HUMAN,tr|B0QYY4|B0QYY4_HUMAN,tr|S4R469|S4R469_HUMAN,tr|A0A0G2JRD1|A0A0G2JRD1_HUMAN,tr|A0A0G2JRA5|A0A0G2JRA5_HUMAN,tr|S4R3K7|S4R3K7_HUMAN" 7 1678.8514 1.97 50246 16549 2 1678.857338 840.433 RNA binding protein fox-1 homolog 2 OS=Homo sapiens OX=9606 GN=RBFOX2 PE=1 SV=3 4.21 2902.6 - 255330 - - - 3.5477 - 3.144 0.657 - 521.4 1 1 0 0.006 17 0 0 0 3.79E+06 1.93E+06 - - - 6.708 0.9856 221125_WJC_METTL3_EV_vs_WT_F04.16550.16550.2 0.000157 Sep-32 K.VSYIPDEQIAQGPENGR.R sp|Q9NZI8|IF2B1_HUMAN 1 1871.9014 3.13 50247 16550 2 1872.901722 936.958 Insulin-like growth factor 2 mRNA-binding protein 1 OS=Homo sapiens OX=9606 GN=IGF2BP1 PE=1 SV=2 4.14 2902.7 - 241097 - - - 534.4117 - 1.736 0.528 - 117.5 1 2 0 1.0004 17 0 0 0 6.23E+06 1.99E+06 - - - 3.9828 0.9876 221125_WJC_METTL3_EV_vs_WT_F04.16553.16553.3 0.00846 Sep-36 R.KIEFPLPDEK.T sp|P62191|PRS4_HUMAN 1 1214.6547 0.47 50249 16553 3 1214.655909 405.8922 26S proteasome regulatory subunit 4 OS=Homo sapiens OX=9606 GN=PSMC1 PE=1 SV=1 4.68 2903.1 - 99303.7 - - - 1.0036 - 1.712 0.146 - 143.6 1 2 0 0.0012 10 0 0 0 4.03E+06 8.49E+06 - - - 1.7376 1 221125_WJC_METTL3_EV_vs_WT_F04.16555.16555.3 1.12E-05 Oct-48 R.TTPSYVAFTDTER[166.11].L "sp|P48741|HSP77_HUMAN,sp|P54652|HSP72_HUMAN,sp|P0DMV8|HS71A_HUMAN,sp|P34931|HS71L_HUMAN,sp|P11142|HSP7C_HUMAN,sp|P0DMV9|HS71B_HUMAN,sp|P17066|HSP76_HUMAN,tr|E9PQQ4|E9PQQ4_HUMAN,tr|E9PNE6|E9PNE6_HUMAN,tr|E9PKE3|E9PKE3_HUMAN,tr|E9PLF4|E9PLF4_HUMAN,tr|Q53FA3|Q53FA3_HUMAN,tr|E9PI65|E9PI65_HUMAN,tr|E9PK54|E9PK54_HUMAN,tr|E9PN25|E9PN25_HUMAN,tr|E9PPY6|E9PPY6_HUMAN,tr|E9PQK7|E9PQK7_HUMAN,tr|A0A0G2JIW1|A0A0G2JIW1_HUMAN" 18 1496.7023 0.15 50251 16555 3 1496.702914 499.908 Putative heat shock 70 kDa protein 7 OS=Homo sapiens OX=9606 GN=HSPA7 PE=5 SV=2 4.37 2903.2 - 5.86E+06 - - - 0.4376 - 1.99 0.507 - 111.3 1 2 0 0.0007 13 0 0 0 6.74E+07 4.60E+08 - - - 6.0581 1 221125_WJC_METTL3_EV_vs_WT_F04.16556.16556.2 6.04E-08 24-Nov R.TTPSYVAFTDTER.L "sp|P48741|HSP77_HUMAN,sp|P54652|HSP72_HUMAN,sp|P0DMV8|HS71A_HUMAN,sp|P34931|HS71L_HUMAN,sp|P11142|HSP7C_HUMAN,sp|P0DMV9|HS71B_HUMAN,sp|P17066|HSP76_HUMAN,tr|E9PQQ4|E9PQQ4_HUMAN,tr|E9PNE6|E9PNE6_HUMAN,tr|E9PKE3|E9PKE3_HUMAN,tr|E9PLF4|E9PLF4_HUMAN,tr|Q53FA3|Q53FA3_HUMAN,tr|E9PI65|E9PI65_HUMAN,tr|E9PK54|E9PK54_HUMAN,tr|E9PN25|E9PN25_HUMAN,tr|E9PPY6|E9PPY6_HUMAN,tr|E9PQK7|E9PQK7_HUMAN,tr|A0A0G2JIW1|A0A0G2JIW1_HUMAN" 18 1486.694 0.15 50252 16556 2 1486.694539 744.3543 Putative heat shock 70 kDa protein 7 OS=Homo sapiens OX=9606 GN=HSPA7 PE=5 SV=2 4.37 2903.3 - 5.58E+06 - - - 0.3699 - 2.377 0.642 - 442.1 1 2 0 0.0006 13 0 0 0 7.60E+08 4.93E+09 - - - 6.0048 1 221125_WJC_METTL3_EV_vs_WT_F04.16558.16558.2 1.99E-08 14/26 K.ATNVVMNYSEIESK.V sp|Q14677|EPN4_HUMAN 1 1583.7501 1.59 50254 16558 2 1583.749559 792.8823 Clathrin interactor 1 OS=Homo sapiens OX=9606 GN=CLINT1 PE=1 SV=1 4.53 2903.4 - 3.98E+06 - - - -0.3561 - 2.803 0.59 - 747.1 1 2 0 -0.0006 14 0 0 0 4.70E+08 2.96E+08 - - - 5.985 0.9999 221125_WJC_METTL3_EV_vs_WT_F04.16560.16560.3 2.08E-08 14/52 K.FEDPK[136.11]FEVIEK[136.11]PQA.- sp|P18859|ATP5J_HUMAN 1 1691.8741 1.99 50256 16560 3 1691.874497 564.9653 "ATP synthase-coupling factor 6, mitochondrial OS=Homo sapiens OX=9606 GN=ATP5PF PE=1 SV=1" 4.41 2903.4 - 2.42E+06 - - - 0.2122 - 2.795 0.591 - 137.4 1 2 1 0.0004 14 0 0 0 3.26E+07 1.64E+07 - - - 7.8605 0.9999 221125_WJC_METTL3_EV_vs_WT_F04.16561.16561.3 3.32E-05 Oct-48 R.QYAGLDHELAFSR.L "sp|Q99720|SGMR1_HUMAN,tr|A0A7P0Z4C2|A0A7P0Z4C2_HUMAN,tr|A0A7P0TA12|A0A7P0TA12_HUMAN,tr|B4DR71|B4DR71_HUMAN,tr|A0A7P0T9D5|A0A7P0T9D5_HUMAN" 5 1505.7263 3.33 50257 16561 3 1505.727362 502.916 Sigma non-opioid intracellular receptor 1 OS=Homo sapiens OX=9606 GN=SIGMAR1 PE=1 SV=1 5.32 2903.5 - 2.42E+06 - - - 0.7106 - 1.987 0.469 - 114.5 1 2 0 0.0011 13 0 0 0 2.13E+07 6.39E+06 - - - 5.6302 0.9999 221125_WJC_METTL3_EV_vs_WT_F04.16562.16562.3 1.59E-05 14/48 R.QYAGLDHELAFSR[166.11].L "sp|Q99720|SGMR1_HUMAN,tr|A0A7P0Z4C2|A0A7P0Z4C2_HUMAN,tr|A0A7P0TA12|A0A7P0TA12_HUMAN,tr|B4DR71|B4DR71_HUMAN,tr|A0A7P0T9D5|A0A7P0T9D5_HUMAN" 5 1515.7346 3.57 50258 16562 3 1515.731881 506.2521 Sigma non-opioid intracellular receptor 1 OS=Homo sapiens OX=9606 GN=SIGMAR1 PE=1 SV=1 5.32 2903.6 - 1.96E+06 - - - -1.7688 - 2.361 0.434 - 287.9 1 2 0 -0.0027 13 0 0 0 2.07E+07 5.80E+06 - - - 5.7072 1 221125_WJC_METTL3_EV_vs_WT_F04.16563.16563.3 5.29E-13 25/76 K.LGHVVMGNNAVSPYQQVIEK.T "sp|P60228|EIF3E_HUMAN,tr|H0YBP5|H0YBP5_HUMAN,tr|A0A7I2V5Z6|A0A7I2V5Z6_HUMAN,tr|A0A7I2V2H9|A0A7I2V2H9_HUMAN,tr|B3KW56|B3KW56_HUMAN,tr|H0YAW4|H0YAW4_HUMAN,tr|A0A7I2V4B4|A0A7I2V4B4_HUMAN,tr|E5RGA2|E5RGA2_HUMAN,tr|A0A7I2V3I0|A0A7I2V3I0_HUMAN,tr|A0A7I2V3S3|A0A7I2V3S3_HUMAN,tr|A0A7I2V4G3|A0A7I2V4G3_HUMAN,tr|E5RHS5|E5RHS5_HUMAN,tr|A0A7I2V2W0|A0A7I2V2W0_HUMAN,tr|A0A7I2V5P9|A0A7I2V5P9_HUMAN" 14 2182.1205 1.72 50259 16563 3 2182.123113 728.3808 Eukaryotic translation initiation factor 3 subunit E OS=Homo sapiens OX=9606 GN=EIF3E PE=1 SV=1 6.75 2903.6 - 1.53E+06 - - - 1.2098 - 4.471 0.54 - 1184.8 1 2 0 0.0026 20 0 0 0 4.17E+07 2.42E+07 - - - 8.193 0.9865 221125_WJC_METTL3_EV_vs_WT_F04.16564.16564.3 0.3 Sep-60 R.SLATTR[166.11]PTVNADDLLK[136.11].V sp|Q9UN37|VPS4A_HUMAN 1 1731.9486 1.15 50260 16564 3 1731.94847 578.3235 Vacuolar protein sorting-associated protein 4A OS=Homo sapiens OX=9606 GN=VPS4A PE=1 SV=1 5.68 2903.7 - 1.27E+06 - - - -0.0658 - 1.325 0.212 - 59 1 2 0 -0.0001 16 0 0 0 1.50E+07 1.30E+07 - - - 1.6256 0.9998 221125_WJC_METTL3_EV_vs_WT_F04.16566.16566.2 8.53E-05 20-Nov K.QAGVFEPTIVK[136.11].V "sp|P17987|TCPA_HUMAN,tr|F5H282|F5H282_HUMAN,tr|E7EQR6|E7EQR6_HUMAN" 3 1195.6692 0.46 50262 16566 2 1195.66987 598.8419 T-complex protein 1 subunit alpha OS=Homo sapiens OX=9606 GN=TCP1 PE=1 SV=1 6 2904 - 582284 - - - 0.5403 - 2.075 0.458 - 317.2 1 2 0 0.0006 11 0 0 0 2.59E+06 5.58E+06 - - - 4.3983 0.9999 221125_WJC_METTL3_EV_vs_WT_F04.16567.16567.2 0.000596 24-Dec K.ASLASLPPLHVAK[136.11].L "sp|Q14203|DCTN1_HUMAN,tr|A0A804CDA6|A0A804CDA6_HUMAN,tr|E7EX90|E7EX90_HUMAN,tr|A0A7P0Z4C3|A0A7P0Z4C3_HUMAN,tr|E7EWF7|E7EWF7_HUMAN" 5 1310.7802 2.06 50263 16567 2 1310.780632 656.3974 Dynactin subunit 1 OS=Homo sapiens OX=9606 GN=DCTN1 PE=1 SV=3 8.8 2904.1 - 430961 - - - 0.3509 - 2.288 0.483 - 346.2 1 2 0 0.0005 13 0 0 0 5.89E+06 2.86E+06 - - - 4.7326 1 221125_WJC_METTL3_EV_vs_WT_F04.16568.16568.2 1.63E-11 17/28 K.NQVAMNPTNTVFDAK.R "sp|P11142|HSP7C_HUMAN,tr|E9PQQ4|E9PQQ4_HUMAN,tr|E9PNE6|E9PNE6_HUMAN,tr|E9PKE3|E9PKE3_HUMAN,tr|E9PLF4|E9PLF4_HUMAN,tr|E9PK54|E9PK54_HUMAN,tr|E9PN25|E9PN25_HUMAN,tr|E9PPY6|E9PPY6_HUMAN,tr|E9PQK7|E9PQK7_HUMAN" 9 1648.7879 0.15 50264 16568 2 1648.787785 825.4012 Heat shock cognate 71 kDa protein OS=Homo sapiens OX=9606 GN=HSPA8 PE=1 SV=1 5.84 2904.2 - 354661 - - - -0.0734 - 3.237 0.696 - 770.5 1 2 0 -0.0001 15 0 0 0 7.54E+08 4.93E+09 - - - 7.0695 1 221125_WJC_METTL3_EV_vs_WT_F04.16569.16569.2 8.70E-07 22-Dec R.ATEALC[160.03]WAEGQR.L "sp|Q969X6|UTP4_HUMAN,tr|H3BPD7|H3BPD7_HUMAN,tr|H3BSH7|H3BSH7_HUMAN,tr|I3L4T9|I3L4T9_HUMAN,tr|J3KSI1|J3KSI1_HUMAN" 5 1390.6299 -1 50265 16569 2 1390.624225 696.3223 U3 small nucleolar RNA-associated protein 4 homolog OS=Homo sapiens OX=9606 GN=UTP4 PE=1 SV=1 4.53 2904.4 - 267072 - - - -4.1161 - 2.641 0.565 - 654.5 1 2 0 -0.0057 12 0 0 0 0.00E+00 0.00E+00 - - - 5.7676 0.9993 221125_WJC_METTL3_EV_vs_WT_F04.16570.16570.2 0.00161 26-Aug K.NGIAGSSLPPPPIK[136.11].H sp|Q9Y5A9|YTHD2_HUMAN 1 1354.77 1.44 50266 16570 2 1354.772359 678.3923 YTH domain-containing family protein 2 OS=Homo sapiens OX=9606 GN=YTHDF2 PE=1 SV=2 8.75 2904.5 - 251568 - - - 1.7405 - 1.765 0.399 - 216.8 1 2 0 0.0024 14 0 0 0 7.40E+06 5.12E+06 - - - 3.413 0.9994 221125_WJC_METTL3_EV_vs_WT_F04.16571.16571.2 0.000381 26-Oct R.SEVTFLAPVTRPDK.V "sp|Q96GK7|FAH2A_HUMAN,tr|C9JGM0|C9JGM0_HUMAN" 2 1558.8355 1.93 50267 16571 2 1558.837655 780.425 Fumarylacetoacetate hydrolase domain-containing protein 2A OS=Homo sapiens OX=9606 GN=FAHD2A PE=1 SV=1 5.79 2904.6 - 214675 - - - 1.3773 - 1.965 0.344 - 271.5 1 2 0 0.0021 14 0 0 0 1.61E+06 8.36E+05 - - - 3.2762 1 221125_WJC_METTL3_EV_vs_WT_F04.16576.16576.3 1.80E-05 13/48 R.TTPSYVAFTDTER.L "sp|P48741|HSP77_HUMAN,sp|P54652|HSP72_HUMAN,sp|P0DMV8|HS71A_HUMAN,sp|P34931|HS71L_HUMAN,sp|P11142|HSP7C_HUMAN,sp|P0DMV9|HS71B_HUMAN,sp|P17066|HSP76_HUMAN,tr|E9PQQ4|E9PQQ4_HUMAN,tr|E9PNE6|E9PNE6_HUMAN,tr|E9PKE3|E9PKE3_HUMAN,tr|E9PLF4|E9PLF4_HUMAN,tr|Q53FA3|Q53FA3_HUMAN,tr|E9PI65|E9PI65_HUMAN,tr|E9PK54|E9PK54_HUMAN,tr|E9PN25|E9PN25_HUMAN,tr|E9PPY6|E9PPY6_HUMAN,tr|E9PQK7|E9PQK7_HUMAN,tr|A0A0G2JIW1|A0A0G2JIW1_HUMAN" 18 1486.694 0.15 50270 16576 3 1486.694136 496.5719 Putative heat shock 70 kDa protein 7 OS=Homo sapiens OX=9606 GN=HSPA7 PE=5 SV=2 4.37 2905.2 - 2.58E+06 - - - 0.0989 - 2.315 0.466 - 221.8 1 2 0 0.0001 13 0 0 0 6.74E+07 4.60E+08 - - - 6.0113 0.9997 221125_WJC_METTL3_EV_vs_WT_F04.16578.16578.3 0.000117 Dec-60 R.LLIYKVSNRFSGVPDR.F sp|A0A075B6R9|KVD24_HUMAN 1 1863.0367 283.06 50272 16578 3 1863.038528 622.0195 Probable non-functional immunoglobulin kappa variable 2D-24 OS=Homo sapiens OX=9606 GN=IGKV2D-24 PE=1 SV=1 9.99 2905.3 - 3.51E+06 - - - 0.9989 - 2.338 0.439 - 208.6 1 2 2 0.0019 16 0 0 0 5.09E+07 1.80E+05 - - - 5.6131 0.9997 221125_WJC_METTL3_EV_vs_WT_F04.16579.16579.3 0.00011 Nov-44 -.MK[136.11]VELC[160.03]SFSGYK[136.11].L "sp|P83731|RL24_HUMAN,tr|C9JNW5|C9JNW5_HUMAN,tr|C9JXB8|C9JXB8_HUMAN" 3 1463.7124 0.78 50273 16579 3 1463.712618 488.9114 60S ribosomal protein L24 OS=Homo sapiens OX=9606 GN=RPL24 PE=1 SV=1 7.93 2905.4 - 1.77E+06 - - - 0.1776 - 2.199 0.434 - 194.6 1 2 1 0.0003 12 0 0 0 1.44E+07 1.85E+07 - - - 5.5628 0.9999 221125_WJC_METTL3_EV_vs_WT_F04.16580.16580.2 5.04E-08 13/22 R.QQQDEAYLASLR[166.11].A sp|Q96CS3|FAF2_HUMAN 1 1430.7029 1.04 50274 16580 2 1430.703245 716.3587 FAS-associated factor 2 OS=Homo sapiens OX=9606 GN=FAF2 PE=1 SV=2 4.37 2905.5 - 1.20E+06 - - - 0.2223 - 2.693 0.521 - 1018 1 2 0 0.0003 12 0 0 0 3.37E+07 3.23E+07 - - - 5.4956 0.9995 221125_WJC_METTL3_EV_vs_WT_F04.16583.16583.3 0.000135 15/72 K.VLPIK[136.11]PADVEEPAVPQTPR[166.11].V "sp|Q96EV2|RBM33_HUMAN,tr|H0Y3K4|H0Y3K4_HUMAN" 2 2073.1589 0.5 50277 16583 3 2073.167413 692.0602 RNA-binding protein 33 OS=Homo sapiens OX=9606 GN=RBM33 PE=1 SV=3 4.68 2905.9 - 483343 - - - 4.101 - 2.511 0.446 - 180.7 1 2 0 0.0085 19 0 0 0 2.52E+06 5.01E+06 - - - 5.772 1 221125_WJC_METTL3_EV_vs_WT_F04.16586.16586.2 2.03E-08 26-Dec R.C[160.03]YVDGSEEIGSDFK.L sp|P78310|CXAR_HUMAN 1 1604.6665 1.76 50280 16586 2 1604.665764 803.3405 Coxsackievirus and adenovirus receptor OS=Homo sapiens OX=9606 GN=CXADR PE=1 SV=1 3.92 2906.3 - 352961 - - - -0.4294 - 2.465 0.63 - 288.5 1 2 0 -0.0007 14 0 0 0 4.35E+06 2.47E+06 - - - 5.958 0.9999 221125_WJC_METTL3_EV_vs_WT_F04.16590.16590.3 0.000121 Dec-48 R.KEFSPFGTITSAK.V "sp|P11940|PABP1_HUMAN,tr|A0A7I2YQE4|A0A7I2YQE4_HUMAN,tr|A0A7I2V649|A0A7I2V649_HUMAN,tr|H0YB86|H0YB86_HUMAN,tr|H0YAR2|H0YAR2_HUMAN,tr|E7ERJ7|E7ERJ7_HUMAN,tr|A0A7I2YQ88|A0A7I2YQ88_HUMAN,tr|A0A087WTT1|A0A087WTT1_HUMAN,tr|H0YAP2|H0YAP2_HUMAN,tr|A0A7I2V4N4|A0A7I2V4N4_HUMAN,tr|E7EQV3|E7EQV3_HUMAN" 11 1411.7347 1.32 50282 16590 3 1411.733018 471.5855 Polyadenylate-binding protein 1 OS=Homo sapiens OX=9606 GN=PABPC1 PE=1 SV=2 8.59 2906.8 - 2.80E+06 - - - -1.2134 - 2.44 0.446 - 214.4 1 2 0 -0.0017 13 0 0 0 2.17E+08 1.64E+08 - - - 5.9305 1 221125_WJC_METTL3_EV_vs_WT_F04.16591.16591.3 7.68E-09 16/56 K.NQVAMNPTNTVFDAK[136.11].R "sp|P11142|HSP7C_HUMAN,tr|E9PQQ4|E9PQQ4_HUMAN,tr|E9PNE6|E9PNE6_HUMAN,tr|E9PKE3|E9PKE3_HUMAN,tr|E9PLF4|E9PLF4_HUMAN,tr|E9PK54|E9PK54_HUMAN,tr|E9PN25|E9PN25_HUMAN,tr|E9PPY6|E9PPY6_HUMAN,tr|E9PQK7|E9PQK7_HUMAN" 9 1656.8021 0.15 50283 16591 3 1656.801967 553.2746 Heat shock cognate 71 kDa protein OS=Homo sapiens OX=9606 GN=HSPA8 PE=1 SV=1 5.84 2906.9 - 2.10E+06 - - - -0.0839 - 3.473 0.611 - 419.5 1 2 0 -0.0001 15 0 0 0 4.14E+07 2.69E+08 - - - 8.6007 0.9999 221125_WJC_METTL3_EV_vs_WT_F04.16592.16592.3 0.000232 13/48 R.K[136.11]EFSPFGTITSAK[136.11].V "sp|P11940|PABP1_HUMAN,tr|A0A7I2YQE4|A0A7I2YQE4_HUMAN,tr|A0A7I2V649|A0A7I2V649_HUMAN,tr|H0YB86|H0YB86_HUMAN,tr|H0YAR2|H0YAR2_HUMAN,tr|E7ERJ7|E7ERJ7_HUMAN,tr|A0A7I2YQ88|A0A7I2YQ88_HUMAN,tr|A0A087WTT1|A0A087WTT1_HUMAN,tr|H0YAP2|H0YAP2_HUMAN,tr|A0A7I2V4N4|A0A7I2V4N4_HUMAN,tr|E7EQV3|E7EQV3_HUMAN" 11 1427.7631 1.32 50284 16592 3 1427.761754 476.9283 Polyadenylate-binding protein 1 OS=Homo sapiens OX=9606 GN=PABPC1 PE=1 SV=2 8.59 2906.9 - 2.30E+06 - - - -0.9644 - 2.262 0.431 - 257.1 1 2 0 -0.0014 13 0 0 0 2.17E+08 1.64E+08 - - - 5.5579 1 221125_WJC_METTL3_EV_vs_WT_F04.16593.16593.2 4.88E-09 22-Dec R.QQQDEAYLASLR.A sp|Q96CS3|FAF2_HUMAN 1 1420.6947 1.05 50285 16593 2 1420.694634 711.3546 FAS-associated factor 2 OS=Homo sapiens OX=9606 GN=FAF2 PE=1 SV=2 4.37 2907 - 2.22E+06 - - - -0.0162 - 2.464 0.658 - 767.1 1 2 0 0 12 0 0 0 3.37E+07 3.22E+07 - - - 6.2737 0.9999 221125_WJC_METTL3_EV_vs_WT_F04.16594.16594.3 0.0033 13/40 K.LDLIHESILHK[136.11].C "sp|P78344|IF4G2_HUMAN,tr|H0YEC5|H0YEC5_HUMAN,tr|H0Y3P2|H0Y3P2_HUMAN,tr|H0YCH5|H0YCH5_HUMAN,tr|H0YD77|H0YD77_HUMAN,tr|D3DQV9|D3DQV9_HUMAN" 6 1324.7594 1.95 50286 16594 3 1324.757505 442.5938 Eukaryotic translation initiation factor 4 gamma 2 OS=Homo sapiens OX=9606 GN=EIF4G2 PE=1 SV=1 5.99 2907.1 - 1.98E+06 - - - -1.4576 - 2.495 0.382 - 220.9 1 2 0 -0.0019 11 0 0 0 5.84E+07 3.00E+07 - - - 5.3957 1 221125_WJC_METTL3_EV_vs_WT_F04.16595.16595.2 1.35E-05 16/24 R.TTAATLMNAYSSR.S "sp|P52732|KIF11_HUMAN,tr|A0A7I2YQY4|A0A7I2YQY4_HUMAN,tr|A0A7I2V3A9|A0A7I2V3A9_HUMAN,tr|A0A7I2V3V3|A0A7I2V3V3_HUMAN" 4 1385.6609 0.45 50287 16595 2 1385.659307 693.8377 Kinesin-like protein KIF11 OS=Homo sapiens OX=9606 GN=KIF11 PE=1 SV=2 8.41 2907.2 - 1.22E+06 - - - -1.1597 - 3.019 0.572 - 1227.8 1 2 0 -0.0016 13 0 0 0 8.66E+07 1.91E+08 - - - 6.1011 1 221125_WJC_METTL3_EV_vs_WT_F04.16598.16598.2 4.59E-08 15/28 R.QSVLC[160.03]GSQNIVLNGK.T "sp|Q9BTE1|DCTN5_HUMAN,tr|H3BUD2|H3BUD2_HUMAN,tr|H3BR94|H3BR94_HUMAN,tr|H3BS05|H3BS05_HUMAN" 4 1615.8352 1.54 50290 16598 2 1615.834306 808.9249 Dynactin subunit 5 OS=Homo sapiens OX=9606 GN=DCTN5 PE=1 SV=1 8.22 2907.5 - 868885 - - - -0.5477 - 3.05 0.569 - 1043.7 1 2 0 -0.0009 15 0 0 0 1.06E+07 6.87E+06 - - - 5.985 1 221125_WJC_METTL3_EV_vs_WT_F04.16599.16599.2 5.26E-10 16/28 R.QSVLC[160.03]GSQNIVLNGK[136.11].T "sp|Q9BTE1|DCTN5_HUMAN,tr|H3BUD2|H3BUD2_HUMAN,tr|H3BR94|H3BR94_HUMAN,tr|H3BS05|H3BS05_HUMAN" 4 1623.8494 1.54 50291 16599 2 1623.850383 812.932 Dynactin subunit 5 OS=Homo sapiens OX=9606 GN=DCTN5 PE=1 SV=1 8.22 2907.7 - 774961 - - - 0.6109 - 3.066 0.645 - 1148.8 1 2 0 0.001 15 0 0 0 1.06E+07 6.87E+06 - - - 6.5591 0.9993 221125_WJC_METTL3_EV_vs_WT_F04.16606.16606.3 3.71E-05 13/52 K.SLEELRLEDYQANR.K "sp|P52948|NUP98_HUMAN,tr|A0A3B3ITD8|A0A3B3ITD8_HUMAN" 2 1734.8537 1.82 50296 16606 3 1734.849829 579.2918 Nuclear pore complex protein Nup98-Nup96 OS=Homo sapiens OX=9606 GN=NUP98 PE=1 SV=4 4.41 2908.5 - 1.45E+06 - - - -2.2181 - 2.16 0.447 - 132.3 1 2 1 -0.0038 14 0 0 0 1.46E+08 8.02E+07 - - - 5.5691 0.9995 221125_WJC_METTL3_EV_vs_WT_F04.16607.16607.2 0.00434 22-Dec K.DQIVDLTVGNNK.T sp|P35527|K1C9_HUMAN 1 1314.6779 999 50297 16607 2 1314.675454 658.3462 "Keratin, type I cytoskeletal 9 OS=Homo sapiens OX=9606 GN=KRT9 PE=1 SV=3" 4.21 2908.6 - 977556 - - - -1.8948 - 2.325 0.35 - 345.3 1 2 0 -0.0025 12 0 0 0 2.27E+08 0.00E+00 - - - 3.8453 1 221125_WJC_METTL3_EV_vs_WT_F04.16609.16609.2 5.14E-08 17/36 R.QGAIVAVTGDGVNDSPALK.K "sp|P05023|AT1A1_HUMAN,sp|P13637|AT1A3_HUMAN,sp|P50993|AT1A2_HUMAN,tr|A0A0A0MT26|A0A0A0MT26_HUMAN,tr|H0Y7C1|H0Y7C1_HUMAN,tr|A0A2R8YEY8|A0A2R8YEY8_HUMAN,tr|B1AKY9|B1AKY9_HUMAN,tr|M0R116|M0R116_HUMAN" 8 1810.9425 1.31 50299 16609 2 1810.939524 906.4785 Sodium\potassium-transporting ATPase subunit alpha-1 OS=Homo sapiens OX=9606 GN=ATP1A1 PE=1 SV=1 4.21 2908.9 - 800752 - - - -1.6389 - 3.304 0.6 - 744.3 1 2 0 -0.003 19 0 0 0 4.11E+07 3.13E+07 - - - 6.41 0.9928 221125_WJC_METTL3_EV_vs_WT_F04.16610.16610.3 0.0326 Oct-36 K.IK[136.11]LDVPEDLR[166.11].Q "sp|Q06787|FMR1_HUMAN,tr|A0A087WY29|A0A087WY29_HUMAN,tr|R9WNI0|R9WNI0_HUMAN,tr|A8MQB8|A8MQB8_HUMAN,tr|A0A087WXI3|A0A087WXI3_HUMAN,tr|Q8IXW7|Q8IXW7_HUMAN,tr|G3V0J0|G3V0J0_HUMAN" 7 1214.699 1.54 50300 16610 3 1214.695857 405.9069 Synaptic functional regulator FMR1 OS=Homo sapiens OX=9606 GN=FMR1 PE=1 SV=1 4.56 2909 - 619199 - - - -2.5529 - 1.844 0.303 - 180.4 1 2 1 -0.0031 10 0 0 0 4.22E+07 2.74E+07 - - - 3.7044 0.9999 221125_WJC_METTL3_EV_vs_WT_F04.16615.16615.2 7.97E-07 19/24 R.KEFSPFGTITSAK.V "sp|P11940|PABP1_HUMAN,tr|A0A7I2YQE4|A0A7I2YQE4_HUMAN,tr|A0A7I2V649|A0A7I2V649_HUMAN,tr|H0YB86|H0YB86_HUMAN,tr|H0YAR2|H0YAR2_HUMAN,tr|E7ERJ7|E7ERJ7_HUMAN,tr|A0A7I2YQ88|A0A7I2YQ88_HUMAN,tr|A0A087WTT1|A0A087WTT1_HUMAN,tr|H0YAP2|H0YAP2_HUMAN,tr|A0A7I2V4N4|A0A7I2V4N4_HUMAN,tr|E7EQV3|E7EQV3_HUMAN" 11 1411.7347 0.97 50303 16615 2 1411.735673 706.8746 Polyadenylate-binding protein 1 OS=Homo sapiens OX=9606 GN=PABPC1 PE=1 SV=2 8.59 2909.7 - 1.67E+06 - - - 0.6673 - 2.803 0.537 - 1103.7 1 2 0 0.0009 13 0 0 0 4.65E+07 4.78E+07 - - - 5.6523 0.988 221125_WJC_METTL3_EV_vs_WT_F04.16616.16616.3 0.0137 Sep-32 K.KWNLDELPK.F "sp|P17844|DDX5_HUMAN,tr|J3QR02|J3QR02_HUMAN,tr|X6RLV5|X6RLV5_HUMAN,tr|A0A7I2V507|A0A7I2V507_HUMAN,tr|J3KTA4|J3KTA4_HUMAN,tr|J3KTQ4|J3KTQ4_HUMAN,tr|A0A7I2V2S0|A0A7I2V2S0_HUMAN,tr|J3QRQ7|J3QRQ7_HUMAN" 8 1141.6132 1.56 50304 16616 3 1141.609708 381.545 Probable ATP-dependent RNA helicase DDX5 OS=Homo sapiens OX=9606 GN=DDX5 PE=1 SV=1 6.07 2909.8 - 1.05E+06 - - - -3.0229 - 1.936 0.179 - 132.8 1 2 0 -0.0035 9 0 0 0 1.42E+07 9.10E+06 - - - 2.5257 0.9999 221125_WJC_METTL3_EV_vs_WT_F04.16617.16617.3 1.54E-08 16/56 K.AYHNSPAYLAYINAK.S "sp|Q969G3|SMCE1_HUMAN,tr|A0A2R8Y855|A0A2R8Y855_HUMAN,tr|A0A2R8YES3|A0A2R8YES3_HUMAN,tr|A0A2U3TZQ7|A0A2U3TZQ7_HUMAN,tr|A0A2R8Y7U4|A0A2R8Y7U4_HUMAN,tr|B4DGM3|B4DGM3_HUMAN,tr|A0A2R8YD78|A0A2R8YD78_HUMAN,tr|J3QKS7|J3QKS7_HUMAN,tr|A0A2R8Y4T4|A0A2R8Y4T4_HUMAN,tr|A0A2R8Y7I9|A0A2R8Y7I9_HUMAN,tr|J3QR61|J3QR61_HUMAN,tr|A0A2R8Y765|A0A2R8Y765_HUMAN,tr|J3KT85|J3KT85_HUMAN" 13 1694.8417 1.98 50305 16617 3 1694.834125 565.9545 SWI\SNF-related matrix-associated actin-dependent regulator of chromatin subfamily E member 1 OS=Homo sapiens OX=9606 GN=SMARCE1 PE=1 SV=2 8.48 2909.9 - 1.62E+06 - - - -4.4435 - 2.8 0.584 - 279.4 1 2 0 -0.0075 15 0 0 0 5.08E+07 2.57E+07 - - - 7.7356 0.9987 221125_WJC_METTL3_EV_vs_WT_F04.16619.16619.3 0.0318 Dec-36 K.IKLDVPEDLR.Q "sp|Q06787|FMR1_HUMAN,tr|A0A087WY29|A0A087WY29_HUMAN,tr|R9WNI0|R9WNI0_HUMAN,tr|A8MQB8|A8MQB8_HUMAN,tr|A0A087WXI3|A0A087WXI3_HUMAN,tr|Q8IXW7|Q8IXW7_HUMAN,tr|G3V0J0|G3V0J0_HUMAN" 7 1196.6765 1.52 50307 16619 3 1196.676074 399.8994 Synaptic functional regulator FMR1 OS=Homo sapiens OX=9606 GN=FMR1 PE=1 SV=1 4.56 2910.1 - 1.07E+06 - - - -0.346 - 2.458 0.281 - 281.3 1 2 1 -0.0004 10 0 0 0 4.22E+07 2.77E+07 - - - 4.2992 1 221125_WJC_METTL3_EV_vs_WT_F04.16620.16620.2 1.92E-08 14/36 R.QGAIVAVTGDGVNDSPALK[136.11].K "sp|P05023|AT1A1_HUMAN,sp|P13637|AT1A3_HUMAN,sp|P50993|AT1A2_HUMAN,tr|A0A0A0MT26|A0A0A0MT26_HUMAN,tr|H0Y7C1|H0Y7C1_HUMAN,tr|A0A2R8YEY8|A0A2R8YEY8_HUMAN,tr|B1AKY9|B1AKY9_HUMAN,tr|M0R116|M0R116_HUMAN" 8 1818.9567 1.31 50308 16620 2 1818.94861 910.4856 Sodium\potassium-transporting ATPase subunit alpha-1 OS=Homo sapiens OX=9606 GN=ATP1A1 PE=1 SV=1 4.21 2910.2 - 951910 - - - -4.4432 - 3.36 0.61 - 465.2 1 2 0 -0.0081 19 0 0 0 4.11E+07 3.13E+07 - - - 6.5235 1 221125_WJC_METTL3_EV_vs_WT_F04.16621.16621.3 1.51E-05 17/52 R.TLTAEEAEEEWER[166.11]R[166.11].N "sp|P35269|T2FA_HUMAN,tr|M0R0R9|M0R0R9_HUMAN" 2 1767.8178 19.08 50309 16621 3 1767.819032 590.2799 General transcription factor IIF subunit 1 OS=Homo sapiens OX=9606 GN=GTF2F1 PE=1 SV=2 4.21 2910.4 - 807106 - - - 0.6703 - 2.549 0.508 - 283.3 1 2 0 0.0012 14 0 0 0 1.59E+08 8.32E+06 - - - 6.69 0.9999 221125_WJC_METTL3_EV_vs_WT_F04.16624.16624.3 0.00882 Dec-52 K.ATNVVMNYSEIESK.V sp|Q14677|EPN4_HUMAN 1 1583.7501 1.7 50310 16624 3 1583.747896 528.924 Clathrin interactor 1 OS=Homo sapiens OX=9606 GN=CLINT1 PE=1 SV=1 4.53 2910.7 - 2.94E+06 - - - -1.4062 - 2.274 0.39 - 132.3 1 2 0 -0.0022 14 0 0 0 4.73E+07 2.78E+07 - - - 5.0708 0.9999 221125_WJC_METTL3_EV_vs_WT_F04.16625.16625.3 3.65E-10 16/56 K.AYHNSPAYLAYINAK[136.11].S "sp|Q969G3|SMCE1_HUMAN,tr|A0A2R8Y855|A0A2R8Y855_HUMAN,tr|A0A2R8YES3|A0A2R8YES3_HUMAN,tr|A0A2U3TZQ7|A0A2U3TZQ7_HUMAN,tr|A0A2R8Y7U4|A0A2R8Y7U4_HUMAN,tr|B4DGM3|B4DGM3_HUMAN,tr|A0A2R8YD78|A0A2R8YD78_HUMAN,tr|J3QKS7|J3QKS7_HUMAN,tr|A0A2R8Y4T4|A0A2R8Y4T4_HUMAN,tr|A0A2R8Y7I9|A0A2R8Y7I9_HUMAN,tr|J3QR61|J3QR61_HUMAN,tr|A0A2R8Y765|A0A2R8Y765_HUMAN,tr|J3KT85|J3KT85_HUMAN" 13 1702.8559 1.98 50311 16625 3 1702.848629 568.6259 SWI\SNF-related matrix-associated actin-dependent regulator of chromatin subfamily E member 1 OS=Homo sapiens OX=9606 GN=SMARCE1 PE=1 SV=2 8.48 2910.8 - 1.70E+06 - - - -4.244 - 2.823 0.634 - 296 1 2 0 -0.0072 15 0 0 0 5.08E+07 2.57E+07 - - - 8.3145 1 221125_WJC_METTL3_EV_vs_WT_F04.16626.16626.3 7.86E-09 20/72 R.QGAIVAVTGDGVNDSPALK.K "sp|P05023|AT1A1_HUMAN,sp|P13637|AT1A3_HUMAN,sp|P50993|AT1A2_HUMAN,tr|A0A0A0MT26|A0A0A0MT26_HUMAN,tr|H0Y7C1|H0Y7C1_HUMAN,tr|A0A2R8YEY8|A0A2R8YEY8_HUMAN,tr|B1AKY9|B1AKY9_HUMAN,tr|M0R116|M0R116_HUMAN" 8 1810.9425 1.06 50312 16626 3 1810.942922 604.6548 Sodium\potassium-transporting ATPase subunit alpha-1 OS=Homo sapiens OX=9606 GN=ATP1A1 PE=1 SV=1 4.21 2910.9 - 1.71E+06 - - - 0.2374 - 3.063 0.544 - 538.7 1 2 0 0.0004 19 0 0 0 2.26E+07 2.13E+07 - - - 7.3551 0.9999 221125_WJC_METTL3_EV_vs_WT_F04.16627.16627.3 0.000418 17/48 R.TTAATLMNAYSSR.S "sp|P52732|KIF11_HUMAN,tr|A0A7I2YQY4|A0A7I2YQY4_HUMAN,tr|A0A7I2V3A9|A0A7I2V3A9_HUMAN,tr|A0A7I2V3V3|A0A7I2V3V3_HUMAN" 4 1385.6609 3.3 50313 16627 3 1385.659298 462.8942 Kinesin-like protein KIF11 OS=Homo sapiens OX=9606 GN=KIF11 PE=1 SV=2 8.41 2911 - 1.22E+06 - - - -1.1662 - 2.345 0.432 - 453.7 1 2 0 -0.0016 13 0 0 0 1.34E+07 4.05E+06 - - - 5.6667 0.9999 221125_WJC_METTL3_EV_vs_WT_F04.16630.16630.2 0.000368 28-Dec K.GVVTNGLDLSPADEK.K "sp|P07197|NFM_HUMAN,tr|E7ESP9|E7ESP9_HUMAN,tr|E7EMV2|E7EMV2_HUMAN" 3 1513.7624 1.09 50316 16630 2 1513.762096 757.8885 Neurofilament medium polypeptide OS=Homo sapiens OX=9606 GN=NEFM PE=1 SV=3 4.03 2911.3 - 378416 - - - -0.2021 - 2.704 0.499 - 442.4 1 2 0 -0.0003 15 0 0 0 9.11E+06 8.33E+06 - - - 5.1721 1 221125_WJC_METTL3_EV_vs_WT_F04.16633.16633.2 2.08E-08 13/26 L.GDVTITNDGATILK.L "sp|P17987|TCPA_HUMAN,sp|P50991|TCPD_HUMAN,tr|F5H726|F5H726_HUMAN,tr|F5H136|F5H136_HUMAN,tr|F5GZI8|F5GZI8_HUMAN,tr|E7ERF2|E7ERF2_HUMAN,tr|F5H676|F5H676_HUMAN" 7 1416.746 0.34 50317 16633 2 1416.747007 709.3803 T-complex protein 1 subunit alpha OS=Homo sapiens OX=9606 GN=TCP1 PE=1 SV=1 4.21 2911.7 - 1.30E+06 - - - 0.6938 - 2.51 0.608 - 520.6 1 1 0 0.001 14 0 0 0 2.42E+07 7.10E+07 - - - 5.8408 0.9999 221125_WJC_METTL3_EV_vs_WT_F04.16634.16634.3 8.87E-05 15/48 K.K[136.11]IFDIDEAEEGVK[136.11].D sp|P20042|IF2B_HUMAN 1 1507.7741 0.61 50318 16634 3 1507.769896 503.5986 Eukaryotic translation initiation factor 2 subunit 2 OS=Homo sapiens OX=9606 GN=EIF2S2 PE=1 SV=2 4.18 2911.8 - 959580 - - - -2.7816 - 2.659 0.482 - 305.4 1 2 0 -0.0042 13 0 0 0 8.63E+06 1.43E+07 - - - 6.5642 1 221125_WJC_METTL3_EV_vs_WT_F04.16636.16636.2 1.20E-05 14/26 K.DFMIQGGDPTGTGR.G sp|Q9Y3C6|PPIL1_HUMAN 1 1450.6511 1.33 50320 16636 2 1450.648572 726.3328 Peptidyl-prolyl cis-trans isomerase-like 1 OS=Homo sapiens OX=9606 GN=PPIL1 PE=1 SV=1 4.21 2912 - 1.54E+06 - - - -1.7275 - 2.444 0.631 - 560 1 2 0 -0.0025 14 0 0 0 2.19E+07 1.65E+07 - - - 5.9433 0.9999 221125_WJC_METTL3_EV_vs_WT_F04.16637.16637.3 2.78E-05 Nov-48 R.ER[166.11]ENVLFLTSGTR[166.11].R "sp|Q14244|MAP7_HUMAN,tr|A0A087WZ40|A0A087WZ40_HUMAN" 2 1540.8112 0.92 50321 16637 3 1540.809778 514.611 Ensconsin OS=Homo sapiens OX=9606 GN=MAP7 PE=1 SV=1 6.24 2912.1 - 1.28E+06 - - - -0.9527 - 2.646 0.473 - 181.5 1 2 1 -0.0015 13 0 0 0 1.82E+07 1.97E+07 - - - 6.4513 1 221125_WJC_METTL3_EV_vs_WT_F04.16641.16641.3 5.68E-08 20/76 R.VPFSPGPAPPPHMGELDQER[166.11].L "sp|Q6Y7W6|GGYF2_HUMAN,tr|A0A7I2V3H7|A0A7I2V3H7_HUMAN,tr|I1E4Y6|I1E4Y6_HUMAN,tr|A0A7I2V516|A0A7I2V516_HUMAN,tr|A0A7I2V3H0|A0A7I2V3H0_HUMAN,tr|C9JHW1|C9JHW1_HUMAN,tr|A0A7I2V361|A0A7I2V361_HUMAN,tr|E7ESB6|E7ESB6_HUMAN" 8 2167.0396 2.94 50325 16641 3 2167.037625 723.3538 GRB10-interacting GYF protein 2 OS=Homo sapiens OX=9606 GN=GIGYF2 PE=1 SV=1 4.65 2912.5 - 735413 - - - -0.9086 - 4.042 0.618 - 429 1 2 0 -0.002 20 0 0 0 5.15E+07 1.75E+07 - - - 8.8181 0.9972 221125_WJC_METTL3_EV_vs_WT_F04.16642.16642.2 7.53E-06 26-Dec K.SLEELRLEDYQANR.K "sp|P52948|NUP98_HUMAN,tr|A0A3B3ITD8|A0A3B3ITD8_HUMAN" 2 1734.8537 2.9 50326 16642 2 1734.856583 868.4341 Nuclear pore complex protein Nup98-Nup96 OS=Homo sapiens OX=9606 GN=NUP98 PE=1 SV=4 4.41 2912.7 - 625518 - - - 1.6751 - 2.151 0.507 - 123.8 1 2 1 0.0029 14 0 0 0 1.09E+07 3.77E+06 - - - 4.7069 1 221125_WJC_METTL3_EV_vs_WT_F04.16645.16645.2 3.57E-06 24-Dec R.FSGSGSGTDFTLK.L "sp|A2NJV5|KV229_HUMAN,sp|A0A087WW87|KV240_HUMAN,sp|P06310|KV230_HUMAN,sp|A0A075B6S2|KVD29_HUMAN,sp|P01614|KVD40_HUMAN,sp|P01615|KVD28_HUMAN,sp|A0A075B6S6|KVD30_HUMAN,sp|A0A075B6P5|KV228_HUMAN,sp|A0A0A0MRZ7|KVD26_HUMAN" 9 1302.6092 4.76 50328 16645 2 1302.608744 652.3119 Immunoglobulin kappa variable 2-29 OS=Homo sapiens OX=9606 GN=IGKV2-29 PE=3 SV=2 5.84 2913 - 2.53E+06 - - - -0.347 - 2.585 0.592 - 253 1 2 0 -0.0005 13 0 0 0 6.64E+07 1.40E+07 - - - 5.8509 1 221125_WJC_METTL3_EV_vs_WT_F04.16647.16647.2 1.34E-09 16/28 K.NQVAMNPTNTVFDAK[136.11].R "sp|P11142|HSP7C_HUMAN,tr|E9PQQ4|E9PQQ4_HUMAN,tr|E9PNE6|E9PNE6_HUMAN,tr|E9PKE3|E9PKE3_HUMAN,tr|E9PLF4|E9PLF4_HUMAN,tr|E9PK54|E9PK54_HUMAN,tr|E9PN25|E9PN25_HUMAN,tr|E9PPY6|E9PPY6_HUMAN,tr|E9PQK7|E9PQK7_HUMAN" 9 1656.8021 0.15 50329 16647 2 1656.798212 829.4083 Heat shock cognate 71 kDa protein OS=Homo sapiens OX=9606 GN=HSPA8 PE=1 SV=1 5.84 2913.2 - 2.38E+08 - - - -2.3503 - 3.26 0.69 - 711 1 2 0 -0.0039 15 0 0 0 7.54E+08 4.93E+09 - - - 7.0414 1 221125_WJC_METTL3_EV_vs_WT_F04.16648.16648.2 9.29E-07 15/26 R.ETLLNSATTSLNSK[136.11].V sp|P50991|TCPD_HUMAN 1 1485.7766 0.34 50330 16648 2 1485.775161 743.8956 T-complex protein 1 subunit delta OS=Homo sapiens OX=9606 GN=CCT4 PE=1 SV=4 6.1 2913.3 - 2.80E+07 - - - -0.9699 - 2.641 0.583 - 860.9 1 2 0 -0.0014 14 0 0 0 1.50E+08 4.47E+08 - - - 5.7837 0.9994 221125_WJC_METTL3_EV_vs_WT_F04.16649.16649.3 0.0386 Oct-52 R.ETLLNSATTSLNSK[136.11].V sp|P50991|TCPD_HUMAN 1 1485.7766 0.42 50331 16649 3 1485.774324 496.2661 T-complex protein 1 subunit delta OS=Homo sapiens OX=9606 GN=CCT4 PE=1 SV=4 6.1 2913.3 - 5.51E+06 - - - -1.5332 - 2.091 0.301 - 188.6 1 2 0 -0.0023 14 0 0 0 3.30E+07 7.84E+07 - - - 3.8555 1 221125_WJC_METTL3_EV_vs_WT_F04.16652.16652.2 2.97E-09 16/28 R.DVQGTDASLDEELDR[166.11].V "sp|Q9UJZ1|STML2_HUMAN,tr|A0A087WYB4|A0A087WYB4_HUMAN" 2 1671.7463 1.42 50334 16652 2 1671.744349 836.8804 "Stomatin-like protein 2, mitochondrial OS=Homo sapiens OX=9606 GN=STOML2 PE=1 SV=1" 3.66 2913.5 - 1.83E+06 - - - -1.1718 - 2.829 0.631 - 851.9 1 2 0 -0.002 15 0 0 0 2.94E+07 2.08E+07 - - - 6.2576 0.9998 221125_WJC_METTL3_EV_vs_WT_F04.16654.16654.3 9.23E-08 16/64 R.IIKDFMIQGGDPTGTGR.G sp|Q9Y3C6|PPIL1_HUMAN 1 1804.9142 1.04 50336 16654 3 1804.911735 602.6453 Peptidyl-prolyl cis-trans isomerase-like 1 OS=Homo sapiens OX=9606 GN=PPIL1 PE=1 SV=1 5.96 2913.8 - 1.64E+06 - - - -1.3485 - 2.909 0.481 - 190.4 1 2 1 -0.0024 17 0 0 0 2.16E+07 2.09E+07 - - - 6.5996 0.9999 221125_WJC_METTL3_EV_vs_WT_F04.16656.16656.3 1.16E-07 18/56 K.FLYQLHETEKEDLIR.E "sp|O75643|U520_HUMAN,tr|A0A494C1A5|A0A494C1A5_HUMAN" 2 1932.9945 1.14 50338 16656 3 1932.995205 645.3388 U5 small nuclear ribonucleoprotein 200 kDa helicase OS=Homo sapiens OX=9606 GN=SNRNP200 PE=1 SV=2 4.83 2914 - 848593 - - - 0.3502 - 3.108 0.567 - 453.4 1 2 1 0.0007 15 0 0 0 1.95E+07 1.70E+07 - - - 7.8203 0.972 221125_WJC_METTL3_EV_vs_WT_F04.16658.16658.2 3.52E-06 20-Nov T.PSYVAFTDTER[166.11].L "sp|P48741|HSP77_HUMAN,sp|P54652|HSP72_HUMAN,sp|P0DMV8|HS71A_HUMAN,sp|P34931|HS71L_HUMAN,sp|P11142|HSP7C_HUMAN,sp|P0DMV9|HS71B_HUMAN,sp|P17066|HSP76_HUMAN,tr|E9PQQ4|E9PQQ4_HUMAN,tr|E9PNE6|E9PNE6_HUMAN,tr|E9PKE3|E9PKE3_HUMAN,tr|E9PLF4|E9PLF4_HUMAN,tr|Q53FA3|Q53FA3_HUMAN,tr|E9PI65|E9PI65_HUMAN,tr|E9PK54|E9PK54_HUMAN,tr|E9PN25|E9PN25_HUMAN,tr|E9PPY6|E9PPY6_HUMAN,tr|E9PQK7|E9PQK7_HUMAN,tr|A0A0G2JIW1|A0A0G2JIW1_HUMAN" 18 1294.6069 0.12 50339 16658 2 1294.610906 648.3107 Putative heat shock 70 kDa protein 7 OS=Homo sapiens OX=9606 GN=HSPA7 PE=5 SV=2 4.37 2914.3 - 360994 - - - 3.0928 - 2.456 0.516 - 517.8 1 1 0 0.004 11 0 0 0 4.26E+06 3.52E+07 - - - 5.2817 0.9999 221125_WJC_METTL3_EV_vs_WT_F04.16660.16660.4 1.41E-07 15/84 K.FLYQLHETEKEDLIR.E "sp|O75643|U520_HUMAN,tr|A0A494C1A5|A0A494C1A5_HUMAN" 2 1932.9945 1.73 50340 16660 4 1932.992335 484.2559 U5 small nuclear ribonucleoprotein 200 kDa helicase OS=Homo sapiens OX=9606 GN=SNRNP200 PE=1 SV=2 4.83 2914.5 - 3.77E+06 - - - -1.1345 - 2.74 0.562 - 146.8 1 2 1 -0.0022 15 0 0 0 3.78E+07 2.19E+07 - - - 4.4777 1 221125_WJC_METTL3_EV_vs_WT_F04.16661.16661.2 1.02E-07 13/24 K.TSQLGDSPFYPGK[136.11].T sp|P49790|NU153_HUMAN 1 1403.6812 1.61 50341 16661 2 1403.679169 702.8479 Nuclear pore complex protein Nup153 OS=Homo sapiens OX=9606 GN=NUP153 PE=1 SV=2 5.5 2914.5 - 2.49E+06 - - - -1.479 - 2.754 0.588 - 433.8 1 2 0 -0.0021 13 0 0 0 1.92E+08 1.19E+08 - - - 5.9833 0.9999 221125_WJC_METTL3_EV_vs_WT_F04.16663.16663.4 1.85E-06 17/84 K.FLYQLHETEK[136.11]EDLIR[166.11].E "sp|O75643|U520_HUMAN,tr|A0A494C1A5|A0A494C1A5_HUMAN" 2 1951.017 1.72 50343 16663 4 1951.014067 488.7615 U5 small nuclear ribonucleoprotein 200 kDa helicase OS=Homo sapiens OX=9606 GN=SNRNP200 PE=1 SV=2 4.83 2914.6 - 2.25E+06 - - - -1.5023 - 3.044 0.522 - 208.5 1 2 1 -0.0029 15 0 0 0 3.77E+07 2.19E+07 - - - 4.167 0.9956 221125_WJC_METTL3_EV_vs_WT_F04.16664.16664.3 0.000499 Nov-64 R.IIK[136.11]DFMIQGGDPTGTGR[166.11].G sp|Q9Y3C6|PPIL1_HUMAN 1 1822.9366 1.04 50344 16664 3 1822.931248 608.6528 Peptidyl-prolyl cis-trans isomerase-like 1 OS=Homo sapiens OX=9606 GN=PPIL1 PE=1 SV=1 5.96 2914.7 - 1.67E+06 - - - -2.9573 - 2.144 0.346 - 106.5 1 2 1 -0.0054 17 0 0 0 2.16E+07 2.09E+07 - - - 4.3228 0.9092 221125_WJC_METTL3_EV_vs_WT_F04.16667.16667.2 0.941 18-May R.SMQDVVEDFK.N sp|P08729|K2C7_HUMAN 1 1196.5383 3.19 50347 16667 2 1196.541648 599.2764 "Keratin, type II cytoskeletal 7 OS=Homo sapiens OX=9606 GN=KRT7 PE=1 SV=5" 4.03 2915.1 - 789581 - - - 2.7655 - 1.023 0.123 - 74.4 1 2 0 0.0033 10 0 0 0 5.96E+07 1.87E+07 - - - 0.0119 0.9996 221125_WJC_METTL3_EV_vs_WT_F04.16668.16668.3 0.00452 Sep-32 K.K[136.11]WNLDELPK[136.11].F "sp|P17844|DDX5_HUMAN,tr|J3QR02|J3QR02_HUMAN,tr|X6RLV5|X6RLV5_HUMAN,tr|A0A7I2V507|A0A7I2V507_HUMAN,tr|J3KTA4|J3KTA4_HUMAN,tr|J3KTQ4|J3KTQ4_HUMAN,tr|A0A7I2V2S0|A0A7I2V2S0_HUMAN,tr|J3QRQ7|J3QRQ7_HUMAN" 8 1157.6416 1.56 50348 16668 3 1157.638634 386.8878 Probable ATP-dependent RNA helicase DDX5 OS=Homo sapiens OX=9606 GN=DDX5 PE=1 SV=1 6.07 2915.2 - 533695 - - - -2.5267 - 1.909 0.382 - 125.6 1 2 0 -0.0029 9 0 0 0 1.42E+07 9.10E+06 - - - 4.7468 1 221125_WJC_METTL3_EV_vs_WT_F04.16673.16673.3 4.40E-08 15/60 K.QHPYTFPGGSGTVFAR.N sp|Q10471|GALT2_HUMAN 1 1720.8322 1.25 50351 16673 3 1720.832292 574.618 Polypeptide N-acetylgalactosaminyltransferase 2 OS=Homo sapiens OX=9606 GN=GALNT2 PE=1 SV=1 8.75 2915.8 - 1.87E+06 - - - 0.0802 - 2.725 0.523 - 302.4 1 2 0 0.0001 16 0 0 0 2.67E+07 2.13E+07 - - - 6.9431 1 221125_WJC_METTL3_EV_vs_WT_F04.16675.16675.2 3.76E-10 18/28 K.GYGFVHFETQEAAER[166.11].A "sp|P11940|PABP1_HUMAN,tr|A0A7I2YQE4|A0A7I2YQE4_HUMAN,tr|A0A7I2V649|A0A7I2V649_HUMAN,tr|H0YAR2|H0YAR2_HUMAN,tr|E7ERJ7|E7ERJ7_HUMAN,tr|A0A7I2YQ88|A0A7I2YQ88_HUMAN,tr|H0YBN4|H0YBN4_HUMAN,tr|E5RGH3|E5RGH3_HUMAN,tr|A0A087WTT1|A0A087WTT1_HUMAN,tr|A0A7I2YQ90|A0A7I2YQ90_HUMAN,tr|A0A7I2V4N4|A0A7I2V4N4_HUMAN,tr|E7EQV3|E7EQV3_HUMAN" 12 1749.7986 1.31 50353 16675 2 1749.793321 875.9066 Polyadenylate-binding protein 1 OS=Homo sapiens OX=9606 GN=PABPC1 PE=1 SV=2 4.75 2916.1 - 754682 - - - -3.0278 - 2.942 0.695 - 1199.3 1 2 0 -0.0053 15 0 0 0 2.07E+07 1.58E+07 - - - 6.8256 0.9808 221125_WJC_METTL3_EV_vs_WT_F04.16677.16677.2 1.52E-07 Dec-34 R.PLEVAIEASNGASDYGNK[136.11].F sp|O15067|PUR4_HUMAN 1 1841.8887 0.12 50355 16677 2 1841.892422 921.9516 Phosphoribosylformylglycinamidine synthase OS=Homo sapiens OX=9606 GN=PFAS PE=1 SV=4 4.14 2916.3 - 694509 - - - 2.036 - 2.786 0.417 - 202.8 1 1 0 0.0037 18 0 0 0 7.85E+05 6.50E+06 - - - 4.6388 0.9874 221125_WJC_METTL3_EV_vs_WT_F04.16678.16678.3 0.000228 Oct-40 F.NKPDIDAWELR.K "sp|P20674|COX5A_HUMAN,tr|H3BNX8|H3BNX8_HUMAN,tr|H3BRI0|H3BRI0_HUMAN" 3 1355.6834 2.9 50356 16678 3 1355.6807 452.9017 "Cytochrome c oxidase subunit 5A, mitochondrial OS=Homo sapiens OX=9606 GN=COX5A PE=1 SV=2" 4.56 2916.4 - 651826 - - - -1.9651 - 1.916 0.464 - 131.9 1 1 0 -0.0027 11 0 0 0 8.40E+06 2.90E+06 - - - 5.5596 0.9928 221125_WJC_METTL3_EV_vs_WT_F04.16679.16679.3 0.00593 Oct-56 R.DVQGTDASLDEELDR[166.11].V "sp|Q9UJZ1|STML2_HUMAN,tr|A0A087WYB4|A0A087WYB4_HUMAN" 2 1671.7463 0.69 50357 16679 3 1671.754473 558.256 "Stomatin-like protein 2, mitochondrial OS=Homo sapiens OX=9606 GN=STOML2 PE=1 SV=1" 3.66 2916.6 - 607928 - - - 4.8841 - 1.78 0.343 - 67.8 1 2 0 0.0082 15 0 0 0 2.54E+06 3.69E+06 - - - 3.8664 1 221125_WJC_METTL3_EV_vs_WT_F04.16680.16680.2 5.21E-06 14/26 K.LEEEQIILEDQNC[160.03]K.L sp|P35579|MYH9_HUMAN 1 1759.8298 0.96 50358 16680 2 1759.825861 880.9222 Myosin-9 OS=Homo sapiens OX=9606 GN=MYH9 PE=1 SV=4 3.91 2916.7 - 551882 - - - -2.2553 - 3.385 0.596 - 785.4 1 2 0 -0.004 14 0 0 0 8.66E+06 9.00E+06 - - - 6.5017 1 221125_WJC_METTL3_EV_vs_WT_F04.16684.16684.3 7.24E-08 13/56 K.GYGFVHFETQEAAER[166.11].A "sp|P11940|PABP1_HUMAN,tr|A0A7I2YQE4|A0A7I2YQE4_HUMAN,tr|A0A7I2V649|A0A7I2V649_HUMAN,tr|H0YAR2|H0YAR2_HUMAN,tr|E7ERJ7|E7ERJ7_HUMAN,tr|A0A7I2YQ88|A0A7I2YQ88_HUMAN,tr|H0YBN4|H0YBN4_HUMAN,tr|E5RGH3|E5RGH3_HUMAN,tr|A0A087WTT1|A0A087WTT1_HUMAN,tr|A0A7I2YQ90|A0A7I2YQ90_HUMAN,tr|A0A7I2V4N4|A0A7I2V4N4_HUMAN,tr|E7EQV3|E7EQV3_HUMAN" 12 1749.7986 1.3 50361 16684 3 1749.795936 584.2735 Polyadenylate-binding protein 1 OS=Homo sapiens OX=9606 GN=PABPC1 PE=1 SV=2 4.75 2917.2 - 2.03E+07 - - - -1.5333 - 2.654 0.598 - 168.4 1 2 0 -0.0027 15 0 0 0 2.63E+08 2.03E+08 - - - 7.7533 0.9596 221125_WJC_METTL3_EV_vs_WT_F04.16685.16685.3 1.69 Sep-52 R.ETLLNSATTSLNSK.V sp|P50991|TCPD_HUMAN 1 1477.7624 0.42 50362 16685 3 1477.757783 493.5947 T-complex protein 1 subunit delta OS=Homo sapiens OX=9606 GN=CCT4 PE=1 SV=4 6.1 2917.2 - 2.20E+06 - - - -3.1257 - 1.993 0.128 - 160 1 2 0 -0.0046 14 0 0 0 3.28E+07 7.84E+07 - - - 1.7985 1 221125_WJC_METTL3_EV_vs_WT_F04.16686.16686.3 3.98E-07 17/56 K.NQVAMNPTNTVFDAK.R "sp|P11142|HSP7C_HUMAN,tr|E9PQQ4|E9PQQ4_HUMAN,tr|E9PNE6|E9PNE6_HUMAN,tr|E9PKE3|E9PKE3_HUMAN,tr|E9PLF4|E9PLF4_HUMAN,tr|E9PK54|E9PK54_HUMAN,tr|E9PN25|E9PN25_HUMAN,tr|E9PPY6|E9PPY6_HUMAN,tr|E9PQK7|E9PQK7_HUMAN" 9 1648.7879 0.15 50363 16686 3 1648.786195 550.6032 Heat shock cognate 71 kDa protein OS=Homo sapiens OX=9606 GN=HSPA8 PE=1 SV=1 5.84 2917.3 - 2.47E+06 - - - -1.0377 - 3.423 0.608 - 517.8 1 2 0 -0.0017 15 0 0 0 4.14E+07 2.69E+08 - - - 8.529 1 221125_WJC_METTL3_EV_vs_WT_F04.16687.16687.3 0.0002 15/56 K.C[160.03]GLPQPC[160.03]PEEHLAFR.V "sp|P98173|FAM3A_HUMAN,tr|A6QRH7|A6QRH7_HUMAN,tr|Q5HY75|Q5HY75_HUMAN,tr|D3DWX8|D3DWX8_HUMAN" 4 1809.8291 1.48 50364 16687 3 1809.827104 604.2836 Protein FAM3A OS=Homo sapiens OX=9606 GN=FAM3A PE=1 SV=2 5.4 2917.4 - 2.18E+06 - - - -1.0808 - 2.739 0.495 - 343.3 1 2 0 -0.002 15 0 0 0 2.22E+07 1.50E+07 - - - 6.6874 1 221125_WJC_METTL3_EV_vs_WT_F04.16689.16689.3 3.01E-07 15/56 K.C[160.03]GLPQPC[160.03]PEEHLAFR[166.11].V "sp|P98173|FAM3A_HUMAN,tr|A6QRH7|A6QRH7_HUMAN,tr|Q5HY75|Q5HY75_HUMAN,tr|D3DWX8|D3DWX8_HUMAN" 4 1819.8373 1.48 50366 16689 3 1819.836365 607.6197 Protein FAM3A OS=Homo sapiens OX=9606 GN=FAM3A PE=1 SV=2 5.4 2917.5 - 1.27E+06 - - - -0.5303 - 2.712 0.51 - 350.1 1 2 0 -0.001 15 0 0 0 2.22E+07 1.50E+07 - - - 6.8291 1 221125_WJC_METTL3_EV_vs_WT_F04.16690.16690.3 5.33E-07 13/52 K.LEEEQIILEDQNC[160.03]K.L sp|P35579|MYH9_HUMAN 1 1759.8298 1.79 50367 16690 3 1759.826425 587.6172 Myosin-9 OS=Homo sapiens OX=9606 GN=MYH9 PE=1 SV=4 3.91 2917.6 - 1.09E+06 - - - -1.9348 - 2.763 0.508 - 356.1 1 2 0 -0.0034 14 0 0 0 1.41E+07 7.88E+06 - - - 6.9036 1 221125_WJC_METTL3_EV_vs_WT_F04.16693.16693.2 4.02E-11 19/30 R.VADFTEQYNEQYGAVR.T sp|Q9BQ04|RBM4B_HUMAN 1 1888.8592 1.56 50370 16693 2 1888.853337 945.4369 RNA-binding protein 4B OS=Homo sapiens OX=9606 GN=RBM4B PE=1 SV=1 4.14 2918 - 658366 - - - -3.0807 - 3.816 0.705 - 1557.1 1 2 0 -0.0058 16 0 0 0 8.80E+07 5.64E+07 - - - 7.5388 0.9999 221125_WJC_METTL3_EV_vs_WT_F04.16695.16695.3 0.286 19/64 R.LGLSC[160.03]ANC[160.03]HTTTTTLWR[166.11].R sp|Q92908|GATA6_HUMAN 1 2000.9436 -1 50372 16695 3 2000.937799 667.9885 Transcription factor GATA-6 OS=Homo sapiens OX=9606 GN=GATA6 PE=1 SV=2 8.08 2918.2 - 594482 - - - -2.8921 - 3.426 0.479 - 409.1 1 2 0 -0.0058 17 0 0 0 0.00E+00 0.00E+00 - - - 6.9896 1 221125_WJC_METTL3_EV_vs_WT_F04.16696.16696.2 5.70E-11 20/30 R.VADFTEQYNEQYGAVR[166.11].T sp|Q9BQ04|RBM4B_HUMAN 1 1898.8674 1.56 50373 16696 2 1898.866206 950.441 RNA-binding protein 4B OS=Homo sapiens OX=9606 GN=RBM4B PE=1 SV=1 4.14 2918.4 - 569290 - - - -0.6425 - 3.855 0.728 - 1749.6 1 2 0 -0.0012 16 0 0 0 8.80E+07 5.64E+07 - - - 7.7351 0.9999 221125_WJC_METTL3_EV_vs_WT_F04.16697.16697.2 2.79E-06 14/34 K.AATESVPC[160.03]SPSPLAGEIR[166.11].R "sp|Q8N9M1|CS047_HUMAN,tr|J3QS16|J3QS16_HUMAN,tr|A0A804HLH2|A0A804HLH2_HUMAN,tr|J9JIE4|J9JIE4_HUMAN,tr|J3QKZ5|J3QKZ5_HUMAN" 5 1850.9072 1.73 50374 16697 2 1850.907882 926.4609 Uncharacterized protein C19orf47 OS=Homo sapiens OX=9606 GN=C19orf47 PE=1 SV=1 4.53 2918.5 - 306881 - - - 0.3777 - 2.604 0.548 - 237.8 1 2 0 0.0007 18 0 0 0 4.80E+06 2.77E+06 - - - 5.4413 0.9998 221125_WJC_METTL3_EV_vs_WT_F04.16699.16699.3 3.14E-05 14/72 K.NLPPSGAVPVTGIPPHVVK[136.11].V "sp|Q13283|G3BP1_HUMAN,tr|A0A7I2V5M7|A0A7I2V5M7_HUMAN,tr|A0A7I2YQM1|A0A7I2YQM1_HUMAN,tr|A0A7P0P2U7|A0A7P0P2U7_HUMAN,tr|A0A7I2YQU8|A0A7I2YQU8_HUMAN,tr|A0A7I2V548|A0A7I2V548_HUMAN,tr|A0A7I2V651|A0A7I2V651_HUMAN,tr|A0A7I2V4D8|A0A7I2V4D8_HUMAN,tr|A0A7I2YQN9|A0A7I2YQN9_HUMAN" 9 1886.0869 1.33 50375 16699 3 1886.082203 629.7029 Ras GTPase-activating protein-binding protein 1 OS=Homo sapiens OX=9606 GN=G3BP1 PE=1 SV=1 8.76 2918.7 - 2.56E+06 - - - -2.4999 - 2.316 0.428 - 166.3 1 2 0 -0.0047 19 0 0 0 7.41E+07 5.56E+07 - - - 5.3738 1 221125_WJC_METTL3_EV_vs_WT_F04.16700.16700.2 8.78E-13 21/28 K.GYGFVHFETQEAAER.A "sp|P11940|PABP1_HUMAN,tr|A0A7I2YQE4|A0A7I2YQE4_HUMAN,tr|A0A7I2V649|A0A7I2V649_HUMAN,tr|H0YAR2|H0YAR2_HUMAN,tr|E7ERJ7|E7ERJ7_HUMAN,tr|A0A7I2YQ88|A0A7I2YQ88_HUMAN,tr|H0YBN4|H0YBN4_HUMAN,tr|E5RGH3|E5RGH3_HUMAN,tr|A0A087WTT1|A0A087WTT1_HUMAN,tr|A0A7I2YQ90|A0A7I2YQ90_HUMAN,tr|A0A7I2V4N4|A0A7I2V4N4_HUMAN,tr|E7EQV3|E7EQV3_HUMAN" 12 1739.7903 1.3 50376 16700 2 1739.784853 870.9025 Polyadenylate-binding protein 1 OS=Homo sapiens OX=9606 GN=PABPC1 PE=1 SV=2 4.75 2918.8 - 2.97E+06 - - - -3.159 - 3.601 0.725 - 1588 1 2 0 -0.0055 15 0 0 0 2.08E+07 1.60E+07 - - - 7.544 1 221125_WJC_METTL3_EV_vs_WT_F04.16703.16703.3 1.42E-08 17/60 R.VADFTEQYNEQYGAVR.T sp|Q9BQ04|RBM4B_HUMAN 1 1888.8592 1.59 50379 16703 3 1888.857246 630.627 RNA-binding protein 4B OS=Homo sapiens OX=9606 GN=RBM4B PE=1 SV=1 4.14 2918.9 - 2.56E+06 - - - -1.0112 - 2.64 0.606 - 405.8 1 2 0 -0.0019 16 0 0 0 6.77E+07 4.25E+07 - - - 7.7867 1 221125_WJC_METTL3_EV_vs_WT_F04.16705.16705.2 3.05E-10 13/26 R.TTPSVVAFTADGER[166.11].L "sp|P38646|GRP75_HUMAN,tr|H0Y8K0|H0Y8K0_HUMAN,tr|A0A7I2V2S7|A0A7I2V2S7_HUMAN,tr|A0A7I2V2G2|A0A7I2V2G2_HUMAN,tr|A0A3B3ITI4|A0A3B3ITI4_HUMAN,tr|A0A7I2V3F7|A0A7I2V3F7_HUMAN,tr|D6RCD7|D6RCD7_HUMAN" 7 1459.7182 0.47 50381 16705 2 1459.715815 730.8664 "Stress-70 protein, mitochondrial OS=Homo sapiens OX=9606 GN=HSPA9 PE=1 SV=2" 4.37 2919.1 - 1.86E+06 - - - -1.6633 - 2.623 0.617 - 636.8 1 2 0 -0.0024 14 0 0 0 1.25E+07 2.66E+07 - - - 6.0173 0.9998 221125_WJC_METTL3_EV_vs_WT_F04.16706.16706.3 7.73E-05 13/60 R.VADFTEQYNEQYGAVR[166.11].T sp|Q9BQ04|RBM4B_HUMAN 1 1898.8674 1.63 50382 16706 3 1898.863236 633.9631 RNA-binding protein 4B OS=Homo sapiens OX=9606 GN=RBM4B PE=1 SV=1 4.14 2919.2 - 1.77E+06 - - - -2.2066 - 2.046 0.446 - 188.5 1 2 0 -0.0042 16 0 0 0 6.76E+07 4.16E+07 - - - 5.3482 0.9999 221125_WJC_METTL3_EV_vs_WT_F04.16707.16707.3 4.02E-05 16/36 R.MVNHFIAEFK[136.11].R "sp|P11142|HSP7C_HUMAN,tr|A8K7Q2|A8K7Q2_HUMAN,tr|E9PKE3|E9PKE3_HUMAN,tr|E9PN89|E9PN89_HUMAN" 4 1242.6311 0.14 50383 16707 3 1242.628895 415.2176 Heat shock cognate 71 kDa protein OS=Homo sapiens OX=9606 GN=HSPA8 PE=1 SV=1 6.5 2919.2 - 1.63E+06 - - - -1.7463 - 2.445 0.466 - 388.4 1 2 0 -0.0022 10 0 0 0 5.21E+06 3.67E+07 - - - 6.3458 1 221125_WJC_METTL3_EV_vs_WT_F04.16708.16708.3 3.70E-10 21/64 R.LGLSC[160.03]ANC[160.03]HTTTTTLWR.R sp|Q92908|GATA6_HUMAN 1 1990.9353 2.61 50384 16708 3 1990.932831 664.6524 Transcription factor GATA-6 OS=Homo sapiens OX=9606 GN=GATA6 PE=1 SV=2 8.08 2919.4 - 1.60E+06 - - - -1.2482 - 3.732 0.47 - 723.2 1 2 0 -0.0025 17 0 0 0 5.42E+06 2.07E+06 - - - 7.1063 0.9998 221125_WJC_METTL3_EV_vs_WT_F04.16709.16709.4 3.16E-07 18/90 K.LEEAEKEAELHLTYLK.S "sp|Q8ND24|RN214_HUMAN,tr|E9PN76|E9PN76_HUMAN" 2 1914.9939 3.32 50385 16709 4 1914.990308 479.7557 RING finger protein 214 OS=Homo sapiens OX=9606 GN=RNF214 PE=1 SV=2 4.64 2919.5 - 1.33E+06 - - - -1.8543 - 2.947 0.489 - 263.3 1 2 1 -0.0036 16 0 0 0 4.87E+06 1.47E+06 - - - 3.862 1 221125_WJC_METTL3_EV_vs_WT_F04.16711.16711.3 6.41E-06 18/56 K.LGDVYVNDAFGTAHR.A "sp|P07205|PGK2_HUMAN,sp|P00558|PGK1_HUMAN" 2 1633.7849 1.09 50387 16711 3 1633.782377 545.6022 Phosphoglycerate kinase 2 OS=Homo sapiens OX=9606 GN=PGK2 PE=1 SV=3 5.21 2919.7 - 646800 - - - -1.5253 - 2.931 0.533 - 385.4 1 2 0 -0.0025 15 0 0 0 6.99E+06 6.41E+06 - - - 7.2877 1 221125_WJC_METTL3_EV_vs_WT_F04.16712.16712.2 3.22E-09 14/28 R.GVTNDQVDPSVDVLK.A sp|Q9Y2P8|RCL1_HUMAN 1 1584.7995 1.23 50388 16712 2 1584.804796 793.407 RNA 3'-terminal phosphate cyclase-like protein OS=Homo sapiens OX=9606 GN=RCL1 PE=1 SV=3 3.93 2919.8 - 637127 - - - 3.3317 - 2.782 0.616 - 509.1 1 2 0 0.0053 15 0 0 0 4.20E+06 3.42E+06 - - - 6.1046 0.9998 221125_WJC_METTL3_EV_vs_WT_F04.16713.16713.3 0.000111 Oct-44 K.K[136.11]QEIFYTAIVNR[166.11].T "sp|Q9NRZ9|HELLS_HUMAN,tr|A0A087WSW7|A0A087WSW7_HUMAN,tr|A0A0B4J1V9|A0A0B4J1V9_HUMAN,tr|F6XU50|F6XU50_HUMAN" 4 1498.8263 0.69 50389 16713 3 1498.823132 500.616 Lymphoid-specific helicase OS=Homo sapiens OX=9606 GN=HELLS PE=1 SV=1 8.59 2920 - 612031 - - - -2.103 - 2.172 0.388 - 137.3 1 2 0 -0.0032 12 0 0 0 2.79E+06 4.04E+06 - - - 5.0149 1 221125_WJC_METTL3_EV_vs_WT_F04.16714.16714.2 1.53E-10 13/30 K.ATC[160.03]IGNNSAAAVSMLK[136.11].Q "sp|P25789|PSA4_HUMAN,tr|H0YKS0|H0YKS0_HUMAN,tr|H0YKT8|H0YKT8_HUMAN,tr|H0YMI6|H0YMI6_HUMAN,tr|H0YMA1|H0YMA1_HUMAN,tr|H0YL69|H0YL69_HUMAN,tr|H0YN18|H0YN18_HUMAN,tr|H0YMZ1|H0YMZ1_HUMAN" 8 1614.7949 2.02 50390 16714 2 1614.793723 808.4047 Proteasome subunit alpha type-4 OS=Homo sapiens OX=9606 GN=PSMA4 PE=1 SV=1 8.27 2920.1 - 589426 - - - -0.7363 - 2.697 0.689 - 467.2 1 2 0 -0.0012 16 0 0 0 1.02E+07 5.07E+06 - - - 6.5688 0.9986 221125_WJC_METTL3_EV_vs_WT_F04.16716.16716.3 9.74E-05 Dec-40 R.TLKIPAMTIAK.N "sp|P10809|CH60_HUMAN,tr|A0A7I2V2X6|A0A7I2V2X6_HUMAN,tr|A0A7I2YQK6|A0A7I2YQK6_HUMAN,tr|A0A7I2V599|A0A7I2V599_HUMAN" 4 1185.7155 1.03 50392 16716 3 1185.711753 396.2458 "60 kDa heat shock protein, mitochondrial OS=Homo sapiens OX=9606 GN=HSPD1 PE=1 SV=2" 10 2920.4 - 440192 - - - -3.1736 - 2.448 0.397 - 187.8 1 2 1 -0.0038 11 0 0 0 9.83E+06 9.53E+06 - - - 5.5084 1 221125_WJC_METTL3_EV_vs_WT_F04.16720.16720.3 5.31E-09 16/56 K.GYGFVHFETQEAAER.A "sp|P11940|PABP1_HUMAN,tr|A0A7I2YQE4|A0A7I2YQE4_HUMAN,tr|A0A7I2V649|A0A7I2V649_HUMAN,tr|H0YAR2|H0YAR2_HUMAN,tr|E7ERJ7|E7ERJ7_HUMAN,tr|A0A7I2YQ88|A0A7I2YQ88_HUMAN,tr|H0YBN4|H0YBN4_HUMAN,tr|E5RGH3|E5RGH3_HUMAN,tr|A0A087WTT1|A0A087WTT1_HUMAN,tr|A0A7I2YQ90|A0A7I2YQ90_HUMAN,tr|A0A7I2V4N4|A0A7I2V4N4_HUMAN,tr|E7EQV3|E7EQV3_HUMAN" 12 1739.7903 1.29 50395 16720 3 1739.788117 580.9374 Polyadenylate-binding protein 1 OS=Homo sapiens OX=9606 GN=PABPC1 PE=1 SV=2 4.75 2920.9 - 5.19E+07 - - - -1.2829 - 3.076 0.669 - 271 1 2 0 -0.0022 15 0 0 0 2.59E+08 2.01E+08 - - - 8.93 0.9999 221125_WJC_METTL3_EV_vs_WT_F04.16721.16721.2 1.16E-06 14/26 R.ETLLNSATTSLNSK.V sp|P50991|TCPD_HUMAN 1 1477.7624 0.34 50396 16721 2 1477.761229 739.8885 T-complex protein 1 subunit delta OS=Homo sapiens OX=9606 GN=CCT4 PE=1 SV=4 6.1 2920.9 - 2.20E+06 - - - -0.7938 - 2.783 0.538 - 828 1 2 0 -0.0012 14 0 0 0 1.50E+08 4.47E+08 - - - 5.5828 0.9999 221125_WJC_METTL3_EV_vs_WT_F04.16723.16723.3 0.000714 13/56 R.ILLNC[160.03]PYC[160.03]TFNADKK.T "sp|Q9H2P0|ADNP_HUMAN,tr|A0A669KBJ7|A0A669KBJ7_HUMAN" 2 1855.8961 1.65 50398 16723 3 1855.891622 619.6393 Activity-dependent neuroprotector homeobox protein OS=Homo sapiens OX=9606 GN=ADNP PE=1 SV=1 8.03 2921 - 1.91E+06 - - - -2.4005 - 2.405 0.473 - 197.2 1 2 0 -0.0045 15 0 0 0 6.21E+06 3.75E+06 - - - 6.1021 1 221125_WJC_METTL3_EV_vs_WT_F04.16725.16725.2 6.77E-09 13/26 R.TTPSVVAFTADGER.L "sp|P38646|GRP75_HUMAN,tr|H0Y8K0|H0Y8K0_HUMAN,tr|A0A7I2V2S7|A0A7I2V2S7_HUMAN,tr|A0A7I2V2G2|A0A7I2V2G2_HUMAN,tr|A0A3B3ITI4|A0A3B3ITI4_HUMAN,tr|A0A7I2V3F7|A0A7I2V3F7_HUMAN,tr|D6RCD7|D6RCD7_HUMAN" 7 1449.71 0.47 50400 16725 2 1449.708713 725.8623 "Stress-70 protein, mitochondrial OS=Homo sapiens OX=9606 GN=HSPA9 PE=1 SV=2" 4.37 2921.3 - 1.84E+06 - - - -0.8691 - 2.697 0.623 - 547 1 2 0 -0.0013 14 0 0 0 1.25E+07 2.66E+07 - - - 6.1318 1 221125_WJC_METTL3_EV_vs_WT_F04.16728.16728.3 3.13E-05 14/40 K.ADFC[160.03]IIHYAGK[136.11].V "sp|P35580|MYH10_HUMAN,sp|P35579|MYH9_HUMAN" 2 1301.6318 0.91 50403 16728 3 1301.630296 434.8845 Myosin-10 OS=Homo sapiens OX=9606 GN=MYH10 PE=1 SV=3 6.78 2921.6 - 1.22E+06 - - - -1.1501 - 2.383 0.504 - 271.2 1 2 0 -0.0015 11 0 0 0 3.09E+07 3.41E+07 - - - 6.6255 0.9999 221125_WJC_METTL3_EV_vs_WT_F04.16729.16729.2 3.67E-05 15/22 R.ISDQNIIPSVTR.S "sp|Q6Y7W6|GGYF2_HUMAN,tr|A0A7I2V3H7|A0A7I2V3H7_HUMAN,tr|I1E4Y6|I1E4Y6_HUMAN,tr|A0A7I2V516|A0A7I2V516_HUMAN,tr|A0A7I2V3H0|A0A7I2V3H0_HUMAN,tr|C9JHW1|C9JHW1_HUMAN,tr|A0A7I2V361|A0A7I2V361_HUMAN,tr|E7ESB6|E7ESB6_HUMAN" 8 1341.7252 2.41 50404 16729 2 1341.724094 671.8699 GRB10-interacting GYF protein 2 OS=Homo sapiens OX=9606 GN=GIGYF2 PE=1 SV=1 5.84 2921.7 - 1.17E+06 - - - -0.8459 - 3.158 0.479 - 753.7 1 2 0 -0.0011 12 0 0 0 8.08E+07 3.35E+07 - - - 5.6042 0.9999 221125_WJC_METTL3_EV_vs_WT_F04.16733.16733.3 0.00135 14/40 R.TVVTGIEMFHK.S sp|P49411|EFTU_HUMAN 1 1260.6536 1.26 50408 16733 3 1260.652465 421.2252 "Elongation factor Tu, mitochondrial OS=Homo sapiens OX=9606 GN=TUFM PE=1 SV=2" 6.41 2922.2 - 827946 - - - -0.9352 - 2.364 0.375 - 205.2 1 2 0 -0.0012 11 0 0 0 3.74E+06 2.96E+06 - - - 5.1647 1 221125_WJC_METTL3_EV_vs_WT_F04.16735.16735.3 3.72E-06 13/36 R.MVNHFIAEFK.R "sp|P11142|HSP7C_HUMAN,tr|A8K7Q2|A8K7Q2_HUMAN,tr|E9PKE3|E9PKE3_HUMAN,tr|E9PN89|E9PN89_HUMAN" 4 1234.6169 0.14 50410 16735 3 1234.615518 412.5462 Heat shock cognate 71 kDa protein OS=Homo sapiens OX=9606 GN=HSPA8 PE=1 SV=1 6.5 2922.4 - 638818 - - - -1.091 - 2.223 0.499 - 214.2 1 2 0 -0.0013 10 0 0 0 5.21E+06 3.67E+07 - - - 6.436 1 221125_WJC_METTL3_EV_vs_WT_F04.16736.16736.3 0.000332 17/52 R.NVNLVLLC[160.03]SEKPSK.T "sp|Q96KR1|ZFR_HUMAN,tr|H0Y8W1|H0Y8W1_HUMAN" 2 1599.8654 1.25 50411 16736 3 1599.867054 534.2958 Zinc finger RNA-binding protein OS=Homo sapiens OX=9606 GN=ZFR PE=1 SV=2 8.2 2922.6 - 591508 - - - 1.0163 - 2.8 0.472 - 307.5 1 2 0 0.0016 14 0 0 0 4.22E+06 3.37E+06 - - - 6.5381 0.9959 221125_WJC_METTL3_EV_vs_WT_F04.16739.16739.3 0.00143 18/56 F.LIQQQYAQVLAQQQK.A "sp|Q6Y7W6|GGYF2_HUMAN,tr|A0A7I2V3H7|A0A7I2V3H7_HUMAN,tr|I1E4Y6|I1E4Y6_HUMAN,tr|A0A7I2V516|A0A7I2V516_HUMAN,tr|A0A7I2V3H0|A0A7I2V3H0_HUMAN,tr|C9JHW1|C9JHW1_HUMAN,tr|A0A7I2V361|A0A7I2V361_HUMAN,tr|E7ESB6|E7ESB6_HUMAN" 8 1785.9737 -1 50414 16739 3 1785.97188 596.3319 GRB10-interacting GYF protein 2 OS=Homo sapiens OX=9606 GN=GIGYF2 PE=1 SV=1 8.59 2922.9 - 401204 - - - -1.0375 - 3.095 0.423 - 482.9 1 1 0 -0.0019 15 0 0 0 0.00E+00 0.00E+00 - - - 6.2036 1 221125_WJC_METTL3_EV_vs_WT_F04.16741.16741.2 2.65E-08 14/26 R.ETVSEESNVLC[160.03]LSK[136.11].S sp|P13639|EF2_HUMAN 1 1601.7698 2.41 50415 16741 2 1601.768738 801.8922 Elongation factor 2 OS=Homo sapiens OX=9606 GN=EEF2 PE=1 SV=4 4.25 2923.2 - 8.77E+06 - - - -0.6649 - 2.737 0.67 - 754.9 1 2 0 -0.0011 14 0 0 0 1.60E+08 6.62E+07 - - - 6.516 1 221125_WJC_METTL3_EV_vs_WT_F04.16743.16743.3 0.000123 Oct-40 K.ADFC[160.03]IIHYAGK.V "sp|P35580|MYH10_HUMAN,sp|P35579|MYH9_HUMAN" 2 1293.6176 0.91 50417 16743 3 1293.616676 432.2131 Myosin-10 OS=Homo sapiens OX=9606 GN=MYH10 PE=1 SV=3 6.78 2923.3 - 3.14E+06 - - - -0.7089 - 2.037 0.493 - 130 1 2 0 -0.0009 11 0 0 0 3.08E+07 3.39E+07 - - - 6.0574 0.9998 221125_WJC_METTL3_EV_vs_WT_F04.16747.16747.3 5.48E-05 16/48 K.LGAQLADLHLDNK[136.11].K "sp|Q9HA64|KT3K_HUMAN,tr|I3L2G3|I3L2G3_HUMAN,tr|I3L139|I3L139_HUMAN" 3 1414.766 0.78 50421 16747 3 1414.76636 472.5959 Ketosamine-3-kinase OS=Homo sapiens OX=9606 GN=FN3KRP PE=1 SV=2 5.21 2923.5 - 1.77E+06 - - - 0.27 - 2.894 0.289 - 427.4 1 2 0 0.0004 13 0 0 0 5.78E+06 7.39E+06 - - - 4.6431 1 221125_WJC_METTL3_EV_vs_WT_F04.16748.16748.3 1.90E-08 20/56 K.LGDVYVNDAFGTAHR[166.11].A "sp|P07205|PGK2_HUMAN,sp|P00558|PGK1_HUMAN" 2 1643.7931 1.11 50422 16748 3 1643.791405 548.9383 Phosphoglycerate kinase 2 OS=Homo sapiens OX=9606 GN=PGK2 PE=1 SV=3 5.21 2923.6 - 1.66E+06 - - - -1.0549 - 3.441 0.64 - 621 1 2 0 -0.0017 15 0 0 0 7.73E+06 6.94E+06 - - - 8.8994 1 221125_WJC_METTL3_EV_vs_WT_F04.16750.16750.3 7.91E-10 19/60 K.QHPYTFPGGSGTVFAR[166.11].N sp|Q10471|GALT2_HUMAN 1 1730.8404 1.18 50424 16750 3 1730.840495 577.9541 Polypeptide N-acetylgalactosaminyltransferase 2 OS=Homo sapiens OX=9606 GN=GALNT2 PE=1 SV=1 8.75 2923.8 - 1.26E+06 - - - 0.041 - 3.365 0.649 - 443.1 1 2 0 0.0001 16 0 0 0 2.67E+07 2.26E+07 - - - 8.8892 0.9999 221125_WJC_METTL3_EV_vs_WT_F04.16752.16752.3 0.00153 13/48 K.HLAGLGLTEAIDK.N "sp|P50454|SERPH_HUMAN,tr|E9PKH2|E9PKH2_HUMAN,tr|E9PJH8|E9PJH8_HUMAN" 3 1336.7351 1.27 50426 16752 3 1336.735957 446.5856 Serpin H1 OS=Homo sapiens OX=9606 GN=SERPINH1 PE=1 SV=2 5.32 2923.9 - 1.03E+06 - - - 0.6673 - 2.141 0.404 - 217.1 1 2 0 0.0009 13 0 0 0 3.38E+06 2.66E+06 - - - 5.108 1 221125_WJC_METTL3_EV_vs_WT_F04.16759.16759.3 3.00E-07 14/44 R.SNLGSVVLQLKK.L sp|O43143|DHX15_HUMAN 1 1284.7765 0.85 50433 16759 3 1284.77612 429.2661 Pre-mRNA-splicing factor ATP-dependent RNA helicase DHX15 OS=Homo sapiens OX=9606 GN=DHX15 PE=1 SV=2 10 2924.8 - 679300 - - - -0.3238 - 2.559 0.558 - 311.4 1 2 0 -0.0004 12 0 0 0 2.27E+06 2.67E+06 - - - 7.3655 1 221125_WJC_METTL3_EV_vs_WT_F04.16764.16764.3 9.06E-10 13/48 K.YYYDGKDYIEFNK.E "sp|P25311|ZA2G_HUMAN,tr|C9JEV0|C9JEV0_HUMAN" 2 1716.7672 177.54 50437 16764 3 1716.769969 573.263 Zinc-alpha-2-glycoprotein OS=Homo sapiens OX=9606 GN=AZGP1 PE=1 SV=2 4.56 2925.3 - 8.84E+06 - - - 1.6397 - 2.471 0.695 - 100.6 1 2 1 0.0028 13 0 0 0 3.43E+07 1.93E+05 - - - 8.7405 0.9983 221125_WJC_METTL3_EV_vs_WT_F04.16765.16765.2 0.000369 20-Nov R.QIEIQFAQGDR.K "sp|O75494|SRS10_HUMAN,sp|Q8WXF0|SRS12_HUMAN,tr|Q5JRI1|Q5JRI1_HUMAN" 3 1303.6521 1.33 50438 16765 2 1303.657727 652.8333 Serine\arginine-rich splicing factor 10 OS=Homo sapiens OX=9606 GN=SRSF10 PE=1 SV=1 4.37 2925.3 - 2.77E+06 - - - 4.344 - 2.226 0.458 - 437.8 1 2 0 0.0057 11 0 0 0 1.44E+07 1.09E+07 - - - 4.5868 0.9999 221125_WJC_METTL3_EV_vs_WT_F04.16767.16767.2 0.00342 20-Dec R.QIEIQFAQGDR[166.11].K "sp|O75494|SRS10_HUMAN,sp|Q8WXF0|SRS12_HUMAN,tr|Q5JRI1|Q5JRI1_HUMAN" 3 1313.6603 1.33 50440 16767 2 1313.660956 657.8374 Serine\arginine-rich splicing factor 10 OS=Homo sapiens OX=9606 GN=SRSF10 PE=1 SV=1 4.37 2925.5 - 2.09E+06 - - - 0.4735 - 2.419 0.451 - 685.7 1 2 0 0.0006 11 0 0 0 1.44E+07 1.09E+07 - - - 4.7616 1 221125_WJC_METTL3_EV_vs_WT_F04.16768.16768.2 1.29E-11 15/26 R.ASFENNC[160.03]EIGC[160.03]FAK.L "sp|P56537|IF6_HUMAN,tr|F8WD20|F8WD20_HUMAN,tr|B7ZBH1|B7ZBH1_HUMAN,tr|A0A0B4J1Y7|A0A0B4J1Y7_HUMAN,tr|F8WDS6|F8WDS6_HUMAN" 5 1645.6865 2.18 50441 16768 2 1645.686218 823.8505 Eukaryotic translation initiation factor 6 OS=Homo sapiens OX=9606 GN=EIF6 PE=1 SV=1 4.53 2925.6 - 1.07E+06 - - - -0.158 - 2.776 0.733 - 599.9 1 2 0 -0.0003 14 0 0 0 6.23E+06 2.85E+06 - - - 7.017 0.9996 221125_WJC_METTL3_EV_vs_WT_F04.16769.16769.3 0.0234 13/52 R.NVNLVLLC[160.03]SEK[136.11]PSK[136.11].T "sp|Q96KR1|ZFR_HUMAN,tr|H0Y8W1|H0Y8W1_HUMAN" 2 1615.8938 1.25 50442 16769 3 1615.896754 539.6386 Zinc finger RNA-binding protein OS=Homo sapiens OX=9606 GN=ZFR PE=1 SV=2 8.2 2925.7 - 866389 - - - 1.8108 - 2.673 0.3 - 210.1 1 2 0 0.0029 14 0 0 0 4.22E+06 3.37E+06 - - - 4.4968 1 221125_WJC_METTL3_EV_vs_WT_F04.16772.16772.3 4.34E-08 14/56 R.SELEEQQMHLNVGLR.K "sp|Q14204|DYHC1_HUMAN,tr|A0A7P0T8N2|A0A7P0T8N2_HUMAN,tr|A0A7P0T9C4|A0A7P0T9C4_HUMAN,tr|A0A7P0TBJ7|A0A7P0TBJ7_HUMAN,tr|A0A7P0T9K2|A0A7P0T9K2_HUMAN,tr|A0A2R8Y706|A0A2R8Y706_HUMAN,tr|A0A7P0T916|A0A7P0T916_HUMAN,tr|A0A7P0TB75|A0A7P0TB75_HUMAN,tr|A0A7P0T8W5|A0A7P0T8W5_HUMAN,tr|A0A7P0TAF3|A0A7P0TAF3_HUMAN,tr|A0A7P0T9F1|A0A7P0T9F1_HUMAN,tr|A0A7P0TAW9|A0A7P0TAW9_HUMAN,tr|A0A7P0TA13|A0A7P0TA13_HUMAN,tr|A0A7P0T7V5|A0A7P0T7V5_HUMAN,tr|A0A7P0T9R4|A0A7P0T9R4_HUMAN,tr|A0A2R8Y5T0|A0A2R8Y5T0_HUMAN,tr|A0A2R8YFZ7|A0A2R8YFZ7_HUMAN,tr|A0A7P0T825|A0A7P0T825_HUMAN,tr|A0A2R8Y6H2|A0A2R8Y6H2_HUMAN,tr|A0A7P0TAM4|A0A7P0TAM4_HUMAN" 20 1781.873 0.26 50445 16772 3 1781.876406 594.965 Cytoplasmic dynein 1 heavy chain 1 OS=Homo sapiens OX=9606 GN=DYNC1H1 PE=1 SV=5 4.75 2926.1 - 674488 - - - 1.8935 - 3.105 0.58 - 279 1 2 0 0.0034 15 0 0 0 3.00E+06 1.14E+07 - - - 7.9619 0.9998 221125_WJC_METTL3_EV_vs_WT_F04.16774.16774.3 0.00238 15/40 R.TLK[136.11]IPAMTIAK[136.11].N "sp|P10809|CH60_HUMAN,tr|A0A7I2V2X6|A0A7I2V2X6_HUMAN,tr|A0A7I2YQK6|A0A7I2YQK6_HUMAN,tr|A0A7I2V599|A0A7I2V599_HUMAN" 4 1201.7439 1.1 50447 16774 3 1201.743423 401.5886 "60 kDa heat shock protein, mitochondrial OS=Homo sapiens OX=9606 GN=HSPD1 PE=1 SV=2" 10 2926.3 - 590972 - - - -0.4102 - 2.406 0.451 - 337.6 1 2 1 -0.0005 11 0 0 0 8.90E+06 8.06E+06 - - - 6.0622 1 221125_WJC_METTL3_EV_vs_WT_F04.16775.16775.2 5.30E-10 15/34 H.HVVPTEPLPAPGPASVTE.- "sp|Q9BQA1|MEP50_HUMAN,tr|H0Y711|H0Y711_HUMAN" 2 1796.9309 - 50448 16775 2 1796.931469 899.4727 Methylosome protein 50 OS=Homo sapiens OX=9606 GN=WDR77 PE=1 SV=1 4.81 2926.4 - 574382 - - - 0.3361 - 3.012 0.671 - 457.6 1 1 0 0.0006 18 0 0 0 - - - - - 6.7076 0.8695 221125_WJC_METTL3_EV_vs_WT_F04.16776.16776.3 2.08 Aug-48 R.EEMHLEDSANFIK.Y "sp|P16615|AT2A2_HUMAN,tr|H7C5W9|H7C5W9_HUMAN" 2 1561.7083 1.41 50449 16776 3 1561.707915 521.5767 Sarcoplasmic\endoplasmic reticulum calcium ATPase 2 OS=Homo sapiens OX=9606 GN=ATP2A2 PE=1 SV=1 4.4 2926.5 - 546576 - - - -0.2196 - 1.325 0.088 - 68.7 1 2 0 -0.0003 13 0 0 0 3.50E+06 2.48E+06 - - - 0.284 0.9999 221125_WJC_METTL3_EV_vs_WT_F04.16777.16777.3 0.00229 Nov-40 K.THIDTVINALK.T sp|O95782|AP2A1_HUMAN 1 1223.6874 1.07 50450 16777 3 1223.687875 408.9031 AP-2 complex subunit alpha-1 OS=Homo sapiens OX=9606 GN=AP2A1 PE=1 SV=3 6.41 2926.7 - 442232 - - - 0.3988 - 2.137 0.395 - 137 1 2 0 0.0005 11 0 0 0 1.36E+06 1.27E+06 - - - 5.1011 0.9999 221125_WJC_METTL3_EV_vs_WT_F04.16779.16779.2 9.10E-06 22-Aug K.VESEQQYFEIEK.R "sp|P12270|TPR_HUMAN,tr|Q5SWX9|Q5SWX9_HUMAN" 2 1527.7093 2.58 50452 16779 2 1527.708261 764.8619 Nucleoprotein TPR OS=Homo sapiens OX=9606 GN=TPR PE=1 SV=3 4.09 2926.9 - 306944 - - - -0.6827 - 2.041 0.515 - 208 1 2 0 -0.001 12 0 0 0 1.41E+06 5.48E+05 - - - 4.7216 0.9998 221125_WJC_METTL3_EV_vs_WT_F04.16780.16780.2 1.15E-05 13/24 K.HLAGLGLTEAIDK.N "sp|P50454|SERPH_HUMAN,tr|E9PKH2|E9PKH2_HUMAN,tr|E9PJH8|E9PJH8_HUMAN" 3 1336.7351 -1 50453 16780 2 1336.733307 669.3748 Serpin H1 OS=Homo sapiens OX=9606 GN=SERPINH1 PE=1 SV=2 5.32 2927.1 - 305865 - - - -1.3151 - 2.453 0.473 - 423.3 1 2 0 -0.0018 13 0 0 0 0.00E+00 0.00E+00 - - - 4.837 0.9993 221125_WJC_METTL3_EV_vs_WT_F04.16783.16783.3 0.0228 Oct-48 K.GLFQNPAVQFHSK.E "sp|Q8NFF5|FAD1_HUMAN,tr|Q5T191|Q5T191_HUMAN,tr|Q5T196|Q5T196_HUMAN" 3 1471.7572 0.24 50455 16783 3 1471.760249 491.593 FAD synthase OS=Homo sapiens OX=9606 GN=FLAD1 PE=1 SV=1 8.76 2927.6 - 392186 - - - 2.073 - 2.054 0.324 - 75.9 1 2 0 0.0031 13 0 0 0 2.04E+06 8.43E+06 - - - 4.103 0.9998 221125_WJC_METTL3_EV_vs_WT_F04.16784.16784.2 0.00018 30-Oct R.AAC[160.03]EQQAVALTLQEDR.A sp|Q9BUH6|PAXX_HUMAN 1 1801.8629 -1 50456 16784 2 1801.861917 901.9387 Protein PAXX OS=Homo sapiens OX=9606 GN=PAXX PE=1 SV=2 4.14 2927.7 - 133205 - - - -0.5245 - 2.149 0.46 - 314 1 2 0 -0.0009 16 0 0 0 0.00E+00 0.00E+00 - - - 4.3191 1 221125_WJC_METTL3_EV_vs_WT_F04.16785.16785.3 2.79E-07 17/56 K.GYAFVHFETQEAADK.A "sp|Q13310|PABP4_HUMAN,tr|A0A7I2V5W9|A0A7I2V5W9_HUMAN,tr|B1ANR0|B1ANR0_HUMAN,tr|A0A7I2V4L7|A0A7I2V4L7_HUMAN,tr|H0YCC8|H0YCC8_HUMAN,tr|A0A7I2V598|A0A7I2V598_HUMAN,tr|H0YEQ8|H0YEQ8_HUMAN,tr|H0Y5F5|H0Y5F5_HUMAN" 8 1711.7842 1.55 50457 16785 3 1711.787958 571.602 Polyadenylate-binding protein 4 OS=Homo sapiens OX=9606 GN=PABPC4 PE=1 SV=1 4.65 2927.7 - 6.13E+06 - - - 2.1948 - 3.021 0.626 - 261.3 1 2 0 0.0038 15 0 0 0 4.35E+07 2.80E+07 - - - 8.4031 0.9997 221125_WJC_METTL3_EV_vs_WT_F04.16787.16787.4 4.15E-05 16/96 K.QVK[136.11]PYVEEGLHPQIIIR[166.11].A "sp|Q99832|TCPH_HUMAN,tr|F8WAM2|F8WAM2_HUMAN" 2 2036.1538 0.17 50459 16787 4 2036.15467 510.0457 T-complex protein 1 subunit eta OS=Homo sapiens OX=9606 GN=CCT7 PE=1 SV=2 6.76 2927.9 - 2.02E+06 - - - 0.444 - 2.921 0.342 - 166.4 1 2 0 0.0009 17 0 0 0 4.62E+06 2.67E+07 - - - 2.5747 1 221125_WJC_METTL3_EV_vs_WT_F04.16788.16788.3 6.10E-09 16/48 R.HPDVEVDGFSELR[166.11].W "sp|P09874|PARP1_HUMAN,tr|A0A7I2V384|A0A7I2V384_HUMAN,tr|A0A7I2V5E9|A0A7I2V5E9_HUMAN,tr|A0A7I2V625|A0A7I2V625_HUMAN,tr|A0A7I2V3E1|A0A7I2V3E1_HUMAN" 5 1508.7135 1.45 50460 16788 3 1508.714523 503.9118 Poly [ADP-ribose] polymerase 1 OS=Homo sapiens OX=9606 GN=PARP1 PE=1 SV=4 4.31 2927.9 - 1.53E+06 - - - 0.6834 - 2.792 0.578 - 368 1 2 0 0.001 13 0 0 0 5.08E+07 3.50E+07 - - - 7.7677 0.9999 221125_WJC_METTL3_EV_vs_WT_F04.16789.16789.2 0.0118 16/30 K.ALQDLENAASGDATVR.Q "sp|Q9NQG5|RPR1B_HUMAN,tr|A2A2M0|A2A2M0_HUMAN" 2 1629.7958 2.72 50461 16789 2 1629.79654 815.9052 Regulation of nuclear pre-mRNA domain-containing protein 1B OS=Homo sapiens OX=9606 GN=RPRD1B PE=1 SV=1 4.03 2928 - 1.31E+06 - - - 0.4369 - 3.241 0.469 - 1093.3 1 2 0 0.0007 16 0 0 0 5.07E+07 1.87E+07 - - - 5.3958 0.9999 221125_WJC_METTL3_EV_vs_WT_F04.16790.16790.2 2.03E-06 14/20 K.ADFC[160.03]IIHYAGK.V "sp|P35580|MYH10_HUMAN,sp|P35579|MYH9_HUMAN" 2 1293.6176 0.63 50462 16790 2 1293.618197 647.8161 Myosin-10 OS=Homo sapiens OX=9606 GN=MYH10 PE=1 SV=3 6.78 2928.1 - 883464 - - - 0.4669 - 2.358 0.553 - 555.1 1 2 0 0.0006 11 0 0 0 3.75E+06 5.96E+06 - - - 5.4459 1 221125_WJC_METTL3_EV_vs_WT_F04.16791.16791.3 1.55E-07 17/56 K.SLYDEVAAQGEVVR[166.11]K[136.11].L "sp|P07814|SYEP_HUMAN,tr|V9GYZ6|V9GYZ6_HUMAN" 2 1680.8802 1.39 50463 16791 3 1680.883109 561.3007 Bifunctional glutamate\proline--tRNA ligase OS=Homo sapiens OX=9606 GN=EPRS1 PE=1 SV=5 4.68 2928.2 - 834025 - - - 1.7485 - 2.74 0.599 - 237.9 1 2 0 0.0029 15 0 0 0 7.37E+06 5.29E+06 - - - 7.8476 1 221125_WJC_METTL3_EV_vs_WT_F04.16793.16793.2 3.78E-06 14/22 K.SR[166.11]LGDLYEEEMR[166.11].E "sp|P08670|VIME_HUMAN,tr|B0YJC4|B0YJC4_HUMAN" 2 1516.7095 4.47 50465 16793 2 1516.709146 759.362 Vimentin OS=Homo sapiens OX=9606 GN=VIM PE=1 SV=4 4.41 2928.4 - 559385 - - - -0.2222 - 2.912 0.555 - 351.1 1 2 1 -0.0003 12 0 0 0 1.74E+07 3.89E+06 - - - 5.9524 0.9999 221125_WJC_METTL3_EV_vs_WT_F04.16796.16796.2 5.14E-06 28-Dec R.DGSLASNPYSGDLTK.F "sp|Q14157|UBP2L_HUMAN,tr|F8W726|F8W726_HUMAN,tr|H7C2T8|H7C2T8_HUMAN,tr|H0Y5H6|H0Y5H6_HUMAN" 4 1523.7104 0.18 50468 16796 2 1523.708891 762.8625 Ubiquitin-associated protein 2-like OS=Homo sapiens OX=9606 GN=UBAP2L PE=1 SV=2 4.21 2928.8 - 402635 - - - -0.9687 - 2.649 0.533 - 353.5 1 2 0 -0.0015 15 0 0 0 6.48E+06 3.64E+07 - - - 5.3723 1 221125_WJC_METTL3_EV_vs_WT_F04.16798.16798.3 2.43E-05 17/64 K.LTGDVEELEIQEK[136.11]PALK[136.11].V "sp|Q9UKF6|CPSF3_HUMAN,tr|G5E9W3|G5E9W3_HUMAN" 2 1927.0485 2.17 50470 16798 3 1927.049696 643.3568 Cleavage and polyadenylation specificity factor subunit 3 OS=Homo sapiens OX=9606 GN=CPSF3 PE=1 SV=1 4.25 2929.1 - 246395 - - - 0.6341 - 2.931 0.503 - 389.1 1 2 0 0.0012 17 0 0 0 1.08E+07 5.00E+06 - - - 6.8643 0.9997 221125_WJC_METTL3_EV_vs_WT_F04.16799.16799.2 3.80E-06 28-Oct K.EANIQAVDSEVGLTK[136.11].E sp|Q9H2G2|SLK_HUMAN 1 1580.8137 0.91 50471 16799 2 1580.814435 791.4141 STE20-like serine\threonine-protein kinase OS=Homo sapiens OX=9606 GN=SLK PE=1 SV=1 4.14 2929.2 - 210877 - - - 0.4548 - 2.204 0.353 - 342.3 1 2 0 0.0007 15 0 0 0 9.18E+05 1.01E+06 - - - 3.591 1 221125_WJC_METTL3_EV_vs_WT_F04.16800.16800.2 7.80E-11 17/36 R.LEGLGSSEADQDGLASTVR[166.11].S sp|Q07065|CKAP4_HUMAN 1 1913.9206 1.39 50472 16800 2 1913.922355 957.9676 Cytoskeleton-associated protein 4 OS=Homo sapiens OX=9606 GN=CKAP4 PE=1 SV=2 3.92 2929.4 - 188571 - - - 0.9253 - 3.593 0.671 - 1002.6 1 2 0 0.0018 19 0 0 0 4.48E+06 3.23E+06 - - - 7.1409 0.9998 221125_WJC_METTL3_EV_vs_WT_F04.16804.16804.3 0.00156 Oct-48 K.HLAGLGLTEAIDK[136.11].N "sp|P50454|SERPH_HUMAN,tr|E9PKH2|E9PKH2_HUMAN,tr|E9PJH8|E9PJH8_HUMAN" 3 1344.7493 1.27 50475 16804 3 1344.747234 449.257 Serpin H1 OS=Homo sapiens OX=9606 GN=SERPINH1 PE=1 SV=2 5.32 2929.8 - 202426 - - - -1.5103 - 2.092 0.374 - 131.4 1 2 0 -0.002 13 0 0 0 3.38E+06 2.66E+06 - - - 4.7104 1 221125_WJC_METTL3_EV_vs_WT_F04.16806.16806.3 8.17E-06 17/60 K.ALQDLENAASGDATVR.Q "sp|Q9NQG5|RPR1B_HUMAN,tr|A2A2M0|A2A2M0_HUMAN" 2 1629.7958 1.71 50477 16806 3 1629.798112 544.2726 Regulation of nuclear pre-mRNA domain-containing protein 1B OS=Homo sapiens OX=9606 GN=RPRD1B PE=1 SV=1 4.03 2929.9 - 4.26E+06 - - - 1.4014 - 3.015 0.538 - 415.1 1 2 0 0.0023 16 0 0 0 3.41E+07 1.99E+07 - - - 7.3692 0.9899 221125_WJC_METTL3_EV_vs_WT_F04.16808.16808.2 0.000321 20-Dec A.TQDGVESLLQK[136.11].F "sp|Q86U44|MTA70_HUMAN,tr|B4E349|B4E349_HUMAN,tr|F5H6D8|F5H6D8_HUMAN,tr|H0YFV6|H0YFV6_HUMAN,tr|B4DTN4|B4DTN4_HUMAN" 5 1224.6441 0.03 50479 16808 2 1224.645657 613.3293 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 4.37 2930 - 2.11E+06 - - - 1.2453 - 2.333 0.492 - 505.3 1 1 0 0.0015 11 0 0 0 4.27E+05 1.28E+07 - - - 4.9662 0.9999 221125_WJC_METTL3_EV_vs_WT_F04.16809.16809.2 3.20E-07 18/30 K.ALQDLENAASGDATVR[166.11].Q "sp|Q9NQG5|RPR1B_HUMAN,tr|A2A2M0|A2A2M0_HUMAN" 2 1639.8041 2.72 50480 16809 2 1639.805376 820.9093 Regulation of nuclear pre-mRNA domain-containing protein 1B OS=Homo sapiens OX=9606 GN=RPRD1B PE=1 SV=1 4.03 2930.1 - 1.87E+06 - - - 0.7794 - 3.089 0.491 - 1374.4 1 2 0 0.0013 16 0 0 0 5.07E+07 1.87E+07 - - - 5.44 1 221125_WJC_METTL3_EV_vs_WT_F04.16810.16810.3 1.48E-10 17/72 R.LEGLGSSEADQDGLASTVR.S sp|Q07065|CKAP4_HUMAN 1 1903.9123 -1 50481 16810 3 1903.916136 635.6447 Cytoskeleton-associated protein 4 OS=Homo sapiens OX=9606 GN=CKAP4 PE=1 SV=2 3.92 2930.2 - 980303 - - - 2.0074 - 3.021 0.617 - 300.9 1 2 0 0.0038 19 0 0 0 0.00E+00 0.00E+00 - - - 8.1341 0.9537 221125_WJC_METTL3_EV_vs_WT_F04.16812.16812.3 0.0825 13/48 K.AGHYLELGAEIAR.T "sp|O60476|MA1A2_HUMAN,tr|H0Y7H1|H0Y7H1_HUMAN,tr|H0Y543|H0Y543_HUMAN" 3 1398.7256 0.48 50483 16812 3 1398.726516 467.2491 "Mannosyl-oligosaccharide 1,2-alpha-mannosidase IB OS=Homo sapiens OX=9606 GN=MAN1A2 PE=1 SV=1" 5.4 2930.4 - 868773 - - - 0.6813 - 2.515 0 - 339.6 2 2 0 0.001 13 0 0 0 4.39E+06 9.10E+06 - - - 0.901 0.9999 221125_WJC_METTL3_EV_vs_WT_F04.16814.16814.3 0.00115 16/64 K.QVK[136.11]PYVEEGLHPQIIIR[166.11].A "sp|Q99832|TCPH_HUMAN,tr|F8WAM2|F8WAM2_HUMAN" 2 2036.1538 0.12 50485 16814 3 2036.157892 679.7252 T-complex protein 1 subunit eta OS=Homo sapiens OX=9606 GN=CCT7 PE=1 SV=2 6.76 2930.6 - 690744 - - - 2.0264 - 3.149 0.453 - 241.4 1 2 0 0.0041 17 0 0 0 5.66E+05 4.71E+06 - - - 6.4872 0.9999 221125_WJC_METTL3_EV_vs_WT_F04.16816.16816.3 0.00712 Dec-40 R.KAYLPQELLGK.E "sp|P51398|RT29_HUMAN,tr|V9GYA7|V9GYA7_HUMAN,tr|V9GZ03|V9GZ03_HUMAN,tr|V9GZ61|V9GZ61_HUMAN,tr|V9GYC9|V9GYC9_HUMAN" 5 1258.7285 1.05 50487 16816 3 1258.729667 420.5835 "28S ribosomal protein S29, mitochondrial OS=Homo sapiens OX=9606 GN=DAP3 PE=1 SV=1" 8.5 2930.8 - 520962 - - - 0.9081 - 2.203 0.437 - 348.5 1 2 0 0.0011 11 0 0 0 4.83E+06 4.60E+06 - - - 5.6555 0.9999 221125_WJC_METTL3_EV_vs_WT_F04.16817.16817.2 7.71E-06 24-Dec R.HPDVEVDGFSELR[166.11].W "sp|P09874|PARP1_HUMAN,tr|A0A7I2V384|A0A7I2V384_HUMAN,tr|A0A7I2V5E9|A0A7I2V5E9_HUMAN,tr|A0A7I2V625|A0A7I2V625_HUMAN,tr|A0A7I2V3E1|A0A7I2V3E1_HUMAN" 5 1508.7135 1.31 50488 16817 2 1508.715636 755.364 Poly [ADP-ribose] polymerase 1 OS=Homo sapiens OX=9606 GN=PARP1 PE=1 SV=4 4.31 2931 - 478475 - - - 1.4211 - 2.481 0.558 - 430.6 1 2 0 0.0021 13 0 0 0 9.17E+06 7.02E+06 - - - 5.4938 0.9993 221125_WJC_METTL3_EV_vs_WT_F04.16820.16820.3 0.000151 Sep-32 K.FYVHNDIFR[166.11].Y "sp|Q13283|G3BP1_HUMAN,tr|A0A7I2V5M7|A0A7I2V5M7_HUMAN,tr|A0A7P0P2U7|A0A7P0P2U7_HUMAN,tr|A0A7I2YQU8|A0A7I2YQU8_HUMAN,tr|A0A7I2V651|A0A7I2V651_HUMAN,tr|A0A7I2YQN9|A0A7I2YQN9_HUMAN,tr|A0A7I2V2V1|A0A7I2V2V1_HUMAN" 7 1219.6014 1.11 50491 16820 3 1219.601035 407.5411 Ras GTPase-activating protein-binding protein 1 OS=Homo sapiens OX=9606 GN=G3BP1 PE=1 SV=1 6.74 2931.4 - 257042 - - - -0.2689 - 1.685 0.306 - 92.8 1 2 0 -0.0003 9 0 0 0 1.09E+07 9.83E+06 - - - 3.524 0.9966 221125_WJC_METTL3_EV_vs_WT_F04.16824.16824.2 2.55E-07 16/22 K.SRLGDLYEEEMR.E "sp|P08670|VIME_HUMAN,tr|B0YJC4|B0YJC4_HUMAN" 2 1496.6929 3.72 50494 16824 2 1496.696837 749.3537 Vimentin OS=Homo sapiens OX=9606 GN=VIM PE=1 SV=4 4.41 2931.8 - 1.39E+06 - - - 2.6017 - 2.978 0.486 - 529.7 1 2 1 0.0039 12 0 0 0 1.38E+07 3.72E+06 - - - 5.5006 0.9997 221125_WJC_METTL3_EV_vs_WT_F04.16825.16825.3 0.061 Oct-40 R.K[136.11]AYLPQELLGK[136.11].E "sp|P51398|RT29_HUMAN,tr|V9GYA7|V9GYA7_HUMAN,tr|V9GZ03|V9GZ03_HUMAN,tr|V9GZ61|V9GZ61_HUMAN,tr|V9GYC9|V9GYC9_HUMAN" 5 1274.7569 1.08 50495 16825 3 1274.757416 425.9263 "28S ribosomal protein S29, mitochondrial OS=Homo sapiens OX=9606 GN=DAP3 PE=1 SV=1" 8.5 2932 - 594952 - - - 0.386 - 2.133 0.32 - 189.7 1 2 0 0.0005 11 0 0 0 4.83E+06 4.48E+06 - - - 4.2596 0.9999 221125_WJC_METTL3_EV_vs_WT_F04.16826.16826.2 6.74E-05 18-Sep K.NMQDMVEDYR.N sp|P04264|K2C1_HUMAN 1 1299.5224 999 50496 16826 2 1299.523676 650.7685 "Keratin, type II cytoskeletal 1 OS=Homo sapiens OX=9606 GN=KRT1 PE=1 SV=6" 4.03 2932 - 3.91E+06 - - - 1.0034 - 2.019 0.568 - 298.4 1 2 0 0.0013 10 0 0 0 8.13E+07 0.00E+00 - - - 5.197 1 221125_WJC_METTL3_EV_vs_WT_F04.16827.16827.3 1.12E-09 21/64 K.LTGDVEELEIQEKPALK.V "sp|Q9UKF6|CPSF3_HUMAN,tr|G5E9W3|G5E9W3_HUMAN" 2 1911.0201 2.19 50497 16827 3 1911.022154 638.014 Cleavage and polyadenylation specificity factor subunit 3 OS=Homo sapiens OX=9606 GN=CPSF3 PE=1 SV=1 4.25 2932.1 - 1.62E+06 - - - 1.0884 - 3.749 0.591 - 692.6 1 2 0 0.0021 17 0 0 0 1.09E+07 5.00E+06 - - - 8.467 1 221125_WJC_METTL3_EV_vs_WT_F04.16828.16828.2 5.21E-14 18/36 R.LEGLGSSEADQDGLASTVR.S sp|Q07065|CKAP4_HUMAN 1 1903.9123 1.39 50498 16828 2 1903.914069 952.9634 Cytoskeleton-associated protein 4 OS=Homo sapiens OX=9606 GN=CKAP4 PE=1 SV=2 3.92 2932.2 - 993433 - - - 0.9218 - 3.57 0.736 - 1072.6 1 2 0 0.0018 19 0 0 0 4.48E+06 3.23E+06 - - - 7.6052 0.9999 221125_WJC_METTL3_EV_vs_WT_F04.16831.16831.3 0.000381 Oct-32 K.FYVHNDIFR.Y "sp|Q13283|G3BP1_HUMAN,tr|A0A7I2V5M7|A0A7I2V5M7_HUMAN,tr|A0A7P0P2U7|A0A7P0P2U7_HUMAN,tr|A0A7I2YQU8|A0A7I2YQU8_HUMAN,tr|A0A7I2V651|A0A7I2V651_HUMAN,tr|A0A7I2YQN9|A0A7I2YQN9_HUMAN,tr|A0A7I2V2V1|A0A7I2V2V1_HUMAN" 7 1209.5931 1.11 50501 16831 3 1209.593938 404.205 Ras GTPase-activating protein-binding protein 1 OS=Homo sapiens OX=9606 GN=G3BP1 PE=1 SV=1 6.74 2932.6 - 731445 - - - 0.6986 - 1.792 0.451 - 124.2 1 2 0 0.0008 9 0 0 0 1.09E+07 9.80E+06 - - - 5.326 1 221125_WJC_METTL3_EV_vs_WT_F04.16833.16833.3 2.51E-05 Dec-44 K.EC[160.03]PFLHIDPESK.L "sp|O95639|CPSF4_HUMAN,tr|C9K0K2|C9K0K2_HUMAN,tr|B7Z7B0|B7Z7B0_HUMAN,tr|H7C016|H7C016_HUMAN" 4 1470.6813 0.88 50503 16833 3 1470.682952 491.2344 Cleavage and polyadenylation specificity factor subunit 4 OS=Homo sapiens OX=9606 GN=CPSF4 PE=1 SV=1 4.65 2932.8 - 678150 - - - 1.1124 - 2.241 0.49 - 164.1 1 2 0 0.0016 12 0 0 0 1.41E+07 1.61E+07 - - - 6.2392 0.9998 221125_WJC_METTL3_EV_vs_WT_F04.16836.16836.2 5.34E-06 15/20 K.HALIIYDDLSK[136.11].Q sp|P25705|ATPA_HUMAN 1 1294.7013 0.79 50506 16836 2 1294.699359 648.3579 "ATP synthase subunit alpha, mitochondrial OS=Homo sapiens OX=9606 GN=ATP5F1A PE=1 SV=1" 5.21 2933.2 - 494047 - - - -1.4629 - 3.028 0.327 - 842.9 1 2 0 -0.0019 11 0 0 0 1.30E+07 1.65E+07 - - - 4.4528 1 221125_WJC_METTL3_EV_vs_WT_F04.16837.16837.2 5.24E-08 17/28 R.IDSANMNDDITTSLR.G "sp|Q9Y2L1|RRP44_HUMAN,tr|G3V1J5|G3V1J5_HUMAN" 2 1664.7676 1.32 50507 16837 2 1664.764492 833.3911 Exosome complex exonuclease RRP44 OS=Homo sapiens OX=9606 GN=DIS3 PE=1 SV=2 3.93 2933.4 - 418112 - - - -1.8453 - 3.439 0.678 - 1079.9 1 2 0 -0.0031 15 0 0 0 3.23E+07 2.45E+07 - - - 7.0845 0.9996 221125_WJC_METTL3_EV_vs_WT_F04.16839.16839.2 0.00231 24-Oct K.VDEIVVLSGDNSK.V "sp|Q14254|FLOT2_HUMAN,tr|E7EMK3|E7EMK3_HUMAN,tr|J3QLD9|J3QLD9_HUMAN" 3 1373.7038 2.07 50509 16839 2 1373.704906 687.8592 Flotillin-2 OS=Homo sapiens OX=9606 GN=FLOT2 PE=1 SV=2 4.03 2933.6 - 346926 - - - 0.7869 - 2.219 0.342 - 362.8 1 2 0 0.0011 13 0 0 0 2.41E+06 1.16E+06 - - - 3.6123 1 221125_WJC_METTL3_EV_vs_WT_F04.16840.16840.2 7.13E-07 15/28 R.IDSANMNDDITTSLR[166.11].G "sp|Q9Y2L1|RRP44_HUMAN,tr|G3V1J5|G3V1J5_HUMAN" 2 1674.7758 1.36 50510 16840 2 1674.773962 838.3952 Exosome complex exonuclease RRP44 OS=Homo sapiens OX=9606 GN=DIS3 PE=1 SV=2 3.93 2933.8 - 303542 - - - -1.1178 - 3.377 0.67 - 928 1 2 0 -0.0019 15 0 0 0 3.21E+07 2.36E+07 - - - 6.9811 0.9999 221125_WJC_METTL3_EV_vs_WT_F04.16841.16841.3 3.28E-05 Sep-40 K.HALIIYDDLSK.Q sp|P25705|ATPA_HUMAN 1 1286.6871 0.9 50511 16841 3 1286.687864 429.903 "ATP synthase subunit alpha, mitochondrial OS=Homo sapiens OX=9606 GN=ATP5F1A PE=1 SV=1" 5.21 2933.9 - 278966 - - - 0.6303 - 1.979 0.423 - 146.4 1 2 0 0.0008 11 0 0 0 7.57E+06 8.41E+06 - - - 5.1949 0.9965 221125_WJC_METTL3_EV_vs_WT_F04.16843.16843.2 0.0641 30-May R.DATGAEEEAPWAATER.R sp|Q8IVS2|FABD_HUMAN 1 1702.7435 2.04 50513 16843 2 1702.744989 852.379 "Malonyl-CoA-acyl carrier protein transacylase, mitochondrial OS=Homo sapiens OX=9606 GN=MCAT PE=1 SV=2" 3.91 2934.2 - 260406 - - - 0.8991 - 1.029 0.328 - 34.9 1 2 0 0.0015 16 0 0 0 2.49E+06 1.22E+06 - - - 1.5334 0.9999 221125_WJC_METTL3_EV_vs_WT_F04.16845.16845.3 3.02E-07 Dec-44 K.SR[166.11]LGDLYEEEMR[166.11].E "sp|P08670|VIME_HUMAN,tr|B0YJC4|B0YJC4_HUMAN" 2 1516.7095 2.73 50514 16845 3 1516.711785 506.5771 Vimentin OS=Homo sapiens OX=9606 GN=VIM PE=1 SV=4 4.41 2934.4 - 3.22E+06 - - - 1.5178 - 2.278 0.591 - 194.8 1 2 1 0.0023 12 0 0 0 6.80E+07 2.49E+07 - - - 7.4105 1 221125_WJC_METTL3_EV_vs_WT_F04.16846.16846.3 2.83E-08 15/60 K.VLSVETPLSIQAHPNK.E "sp|P34949|MPI_HUMAN,tr|H3BPB8|H3BPB8_HUMAN,tr|H3BP57|H3BP57_HUMAN,tr|H3BT48|H3BT48_HUMAN,tr|H3BPU7|H3BPU7_HUMAN,tr|H3BUZ9|H3BUZ9_HUMAN,tr|H3BT46|H3BT46_HUMAN,tr|H3BPM5|H3BPM5_HUMAN,tr|B4DYB8|B4DYB8_HUMAN,tr|H3BPP3|H3BPP3_HUMAN,tr|H3BN01|H3BN01_HUMAN,tr|F5GX71|F5GX71_HUMAN,tr|H3BMZ9|H3BMZ9_HUMAN,tr|H3BNY8|H3BNY8_HUMAN" 14 1731.9519 1.73 50515 16846 3 1731.95348 578.3246 Mannose-6-phosphate isomerase OS=Homo sapiens OX=9606 GN=MPI PE=1 SV=2 6.72 2934.4 - 2.38E+06 - - - 0.8921 - 2.766 0.587 - 289.1 1 2 0 0.0015 16 0 0 0 1.49E+07 8.63E+06 - - - 7.6946 0.9999 221125_WJC_METTL3_EV_vs_WT_F04.16847.16847.3 4.69E-06 Nov-72 K.NLPPSGAVPVTGIPPHVVK.V "sp|Q13283|G3BP1_HUMAN,tr|A0A7I2V5M7|A0A7I2V5M7_HUMAN,tr|A0A7I2YQM1|A0A7I2YQM1_HUMAN,tr|A0A7P0P2U7|A0A7P0P2U7_HUMAN,tr|A0A7I2YQU8|A0A7I2YQU8_HUMAN,tr|A0A7I2V548|A0A7I2V548_HUMAN,tr|A0A7I2V651|A0A7I2V651_HUMAN,tr|A0A7I2V4D8|A0A7I2V4D8_HUMAN,tr|A0A7I2YQN9|A0A7I2YQN9_HUMAN" 9 1878.0727 1.34 50516 16847 3 1878.075809 627.0315 Ras GTPase-activating protein-binding protein 1 OS=Homo sapiens OX=9606 GN=G3BP1 PE=1 SV=1 8.76 2934.5 - 2.96E+06 - - - 1.6458 - 2.291 0.508 - 85.1 1 2 0 0.0031 19 0 0 0 2.60E+07 1.93E+07 - - - 6.2395 0.9999 221125_WJC_METTL3_EV_vs_WT_F04.16849.16849.2 2.17E-06 16/22 R.ISDQNIIPSVTR[166.11].S "sp|Q6Y7W6|GGYF2_HUMAN,tr|A0A7I2V3H7|A0A7I2V3H7_HUMAN,tr|I1E4Y6|I1E4Y6_HUMAN,tr|A0A7I2V516|A0A7I2V516_HUMAN,tr|A0A7I2V3H0|A0A7I2V3H0_HUMAN,tr|C9JHW1|C9JHW1_HUMAN,tr|A0A7I2V361|A0A7I2V361_HUMAN,tr|E7ESB6|E7ESB6_HUMAN" 8 1351.7335 2.75 50518 16849 2 1351.734698 676.874 GRB10-interacting GYF protein 2 OS=Homo sapiens OX=9606 GN=GIGYF2 PE=1 SV=1 5.84 2934.6 - 1.88E+06 - - - 0.887 - 3.165 0.441 - 848.1 1 2 0 0.0012 12 0 0 0 7.61E+07 2.77E+07 - - - 5.3294 0.9997 221125_WJC_METTL3_EV_vs_WT_F04.16850.16850.2 0.00396 20-Nov R.QITVNDLPVGR[166.11].S "sp|Q06830|PRDX1_HUMAN,sp|P32119|PRDX2_HUMAN,tr|A0A0A0MRQ5|A0A0A0MRQ5_HUMAN,tr|A0A0A0MSI0|A0A0A0MSI0_HUMAN" 4 1220.6753 0.78 50519 16850 2 1220.676413 611.3449 Peroxiredoxin-1 OS=Homo sapiens OX=9606 GN=PRDX1 PE=1 SV=1 5.84 2934.7 - 1.78E+06 - - - 0.9478 - 2.177 0.388 - 576.8 1 2 0 0.0012 11 0 0 0 9.94E+06 1.28E+07 - - - 4.0109 0.9998 221125_WJC_METTL3_EV_vs_WT_F04.16851.16851.2 0.000221 20-Nov R.QITVNDLPVGR.S "sp|Q06830|PRDX1_HUMAN,sp|P32119|PRDX2_HUMAN,tr|A0A0A0MRQ5|A0A0A0MRQ5_HUMAN,tr|A0A0A0MSI0|A0A0A0MSI0_HUMAN" 4 1210.667 0.78 50520 16851 2 1210.667439 606.3408 Peroxiredoxin-1 OS=Homo sapiens OX=9606 GN=PRDX1 PE=1 SV=1 5.84 2934.8 - 1.36E+06 - - - 0.3742 - 1.945 0.442 - 558.6 1 2 0 0.0005 11 0 0 0 9.94E+06 1.28E+07 - - - 4.1052 0.9999 221125_WJC_METTL3_EV_vs_WT_F04.16852.16852.3 0.00136 Nov-40 K.GK[136.11]PLALVEEIR[166.11].N "sp|Q9BSD7|NTPCR_HUMAN,tr|Q5TDF0|Q5TDF0_HUMAN" 2 1241.7462 1.12 50521 16852 3 1241.746493 414.9227 Cancer-related nucleoside-triphosphatase OS=Homo sapiens OX=9606 GN=NTPCR PE=1 SV=1 6.14 2934.9 - 1.35E+06 - - - 0.2021 - 2.369 0.42 - 239.4 1 2 0 0.0003 11 0 0 0 2.53E+07 2.25E+07 - - - 5.6726 0.9993 221125_WJC_METTL3_EV_vs_WT_F04.16857.16857.3 0.00265 Dec-68 R.TDGFAEAIHSPQVAGVPR.F sp|P12270|TPR_HUMAN 1 1850.9275 1.7 50526 16857 3 1850.932836 617.9831 Nucleoprotein TPR OS=Homo sapiens OX=9606 GN=TPR PE=1 SV=3 5.29 2935.5 - 447536 - - - 2.8769 - 1.844 0.401 - 63.2 1 2 0 0.0053 18 0 0 0 3.03E+06 1.78E+06 - - - 4.5331 1 221125_WJC_METTL3_EV_vs_WT_F04.16859.16859.3 1.18E-07 Dec-80 R.AVAVDSTGTYMATSGLDHQLK.L "sp|O15213|WDR46_HUMAN,tr|A0A0G2JJL1|A0A0G2JJL1_HUMAN,tr|A0A140T9L0|A0A140T9L0_HUMAN,tr|H0Y6G3|H0Y6G3_HUMAN" 4 2164.047 1.08 50528 16859 3 2164.04958 722.3563 WD repeat-containing protein 46 OS=Homo sapiens OX=9606 GN=WDR46 PE=1 SV=3 5.21 2935.7 - 350849 - - - 1.1765 - 2.453 0.561 - 118.2 1 2 0 0.0025 21 0 0 0 2.12E+06 1.97E+06 - - - 6.9452 0.994 221125_WJC_METTL3_EV_vs_WT_F04.16860.16860.3 0.136 Oct-48 K.NGTLILSPVDIK[136.11]K[136.11].L "sp|Q8NDD1|CA131_HUMAN,tr|Q5TBI2|Q5TBI2_HUMAN" 2 1412.8574 1.26 50529 16860 3 1412.859436 471.9597 Uncharacterized protein C1orf131 OS=Homo sapiens OX=9606 GN=C1orf131 PE=1 SV=4 8.59 2935.8 - 278310 - - - 1.4651 - 1.697 0.212 - 101.2 1 2 0 0.0021 13 0 0 0 1.57E+06 1.25E+06 - - - 2.3369 1 221125_WJC_METTL3_EV_vs_WT_F04.16864.16864.3 8.99E-07 Dec-44 K.EC[160.03]PFLHIDPESK[136.11].L "sp|O95639|CPSF4_HUMAN,tr|C9K0K2|C9K0K2_HUMAN,tr|B7Z7B0|B7Z7B0_HUMAN,tr|H7C016|H7C016_HUMAN" 4 1478.6955 1.07 50532 16864 3 1478.697863 493.9058 Cleavage and polyadenylation specificity factor subunit 4 OS=Homo sapiens OX=9606 GN=CPSF4 PE=1 SV=1 4.65 2936.4 - 1.22E+06 - - - 1.5872 - 2.458 0.527 - 192.2 1 2 0 0.0023 12 0 0 0 1.36E+07 1.26E+07 - - - 6.9077 0.9999 221125_WJC_METTL3_EV_vs_WT_F04.16867.16867.3 0.108 13/40 K.GKPLALVEEIR.N "sp|Q9BSD7|NTPCR_HUMAN,tr|Q5TDF0|Q5TDF0_HUMAN" 2 1223.7238 1.12 50534 16867 3 1223.724104 408.9152 Cancer-related nucleoside-triphosphatase OS=Homo sapiens OX=9606 GN=NTPCR PE=1 SV=1 6.14 2936.7 - 2.29E+06 - - - 0.2713 - 2.534 0.348 - 293 1 2 0 0.0003 11 0 0 0 2.53E+07 2.25E+07 - - - 5.0612 0.9853 221125_WJC_METTL3_EV_vs_WT_F04.16868.16868.3 0.00111 Dec-40 K.K[136.11]FAEAFEAIPR[166.11].A sp|P50990|TCPQ_HUMAN 1 1295.6993 0.25 50535 16868 3 1295.70112 432.907 T-complex protein 1 subunit theta OS=Homo sapiens OX=9606 GN=CCT8 PE=1 SV=4 6.14 2936.8 - 2.07E+06 - - - 1.4108 - 2.018 0.11 - 196.5 1 2 0 0.0018 11 0 0 0 3.20E+06 1.27E+07 - - - 1.7605 1 221125_WJC_METTL3_EV_vs_WT_F04.16870.16870.2 9.07E-06 13/22 R.NQLTSLPSAIC[160.03]K.L "sp|Q13045|FLII_HUMAN,tr|J3KS54|J3KS54_HUMAN,tr|J3QQQ2|J3QQQ2_HUMAN" 3 1330.6915 0.84 50537 16870 2 1330.694214 666.353 Protein flightless-1 homolog OS=Homo sapiens OX=9606 GN=FLII PE=1 SV=2 8.22 2936.9 - 998313 - - - 2.0501 - 2.827 0.55 - 676.9 1 2 0 0.0027 12 0 0 0 8.20E+06 9.74E+06 - - - 5.8368 0.9998 221125_WJC_METTL3_EV_vs_WT_F04.16871.16871.3 2.45E-07 13/56 K.LPVPAAAPTPWETHK.G "sp|Q12788|TBL3_HUMAN,tr|J3KNP2|J3KNP2_HUMAN" 2 1613.8566 1.37 50538 16871 3 1613.861171 538.9595 Transducin beta-like protein 3 OS=Homo sapiens OX=9606 GN=TBL3 PE=1 SV=2 6.75 2937 - 822443 - - - 2.846 - 2.513 0.448 - 281.9 1 2 0 0.0046 15 0 0 0 8.59E+06 6.29E+06 - - - 5.938 0.9982 221125_WJC_METTL3_EV_vs_WT_F04.16873.16873.3 0.012 13/56 R.IDSANMNDDITTSLR[166.11].G "sp|Q9Y2L1|RRP44_HUMAN,tr|G3V1J5|G3V1J5_HUMAN" 2 1674.7758 0.96 50540 16873 3 1674.769268 559.2659 Exosome complex exonuclease RRP44 OS=Homo sapiens OX=9606 GN=DIS3 PE=1 SV=2 3.93 2937.3 - 574033 - - - -3.9205 - 1.874 0.38 - 85.4 1 2 0 -0.0066 15 0 0 0 4.88E+06 5.08E+06 - - - 4.4137 0.9997 221125_WJC_METTL3_EV_vs_WT_F04.16875.16875.3 0.00563 14/40 K.KFAEAFEAIPR.A sp|P50990|TCPQ_HUMAN 1 1277.6768 0.25 50542 16875 3 1277.678011 426.8996 T-complex protein 1 subunit theta OS=Homo sapiens OX=9606 GN=CCT8 PE=1 SV=4 6.14 2937.5 - 566261 - - - 0.9306 - 2.191 0.307 - 264.3 1 2 0 0.0012 11 0 0 0 3.20E+06 1.27E+07 - - - 4.1906 1 221125_WJC_METTL3_EV_vs_WT_F04.16876.16876.3 2.22E-09 19/84 R.AGAIAPC[160.03]EVTVPAQNTGLGPEK.T "sp|Q8NHW5|RLA0L_HUMAN,sp|P05388|RLA0_HUMAN,tr|G3V210|G3V210_HUMAN,tr|F8VU65|F8VU65_HUMAN,tr|F8VWS0|F8VWS0_HUMAN,tr|F8VW21|F8VW21_HUMAN,tr|F8VRK7|F8VRK7_HUMAN,tr|F8VQY6|F8VQY6_HUMAN,tr|F8VPE8|F8VPE8_HUMAN" 9 2179.0943 1.25 50543 16876 3 2179.095445 727.372 60S acidic ribosomal protein P0-like OS=Homo sapiens OX=9606 GN=RPLP0P6 PE=5 SV=1 4.53 2937.6 - 500742 - - - 0.5167 - 3.402 0.611 - 378.5 1 2 0 0.0011 22 0 0 0 2.20E+07 1.76E+07 - - - 8.2545 0.9998 221125_WJC_METTL3_EV_vs_WT_F04.16877.16877.2 4.73E-09 13/26 K.QAAGVISLPVGGNK.D "sp|Q96T37|RBM15_HUMAN,tr|A0A494C001|A0A494C001_HUMAN,tr|A0A499FJY3|A0A499FJY3_HUMAN,tr|A0A087WWP4|A0A087WWP4_HUMAN" 4 1309.7354 1.06 50544 16877 2 1309.737181 655.875 RNA-binding protein 15 OS=Homo sapiens OX=9606 GN=RBM15 PE=1 SV=2 8.75 2937.8 - 414711 - - - 1.3598 - 2.737 0.469 - 444.3 1 2 0 0.0018 14 0 0 0 9.04E+06 8.53E+06 - - - 5.0311 0.9999 221125_WJC_METTL3_EV_vs_WT_F04.16879.16879.3 0.00019 Oct-44 K.HGDGTTLDIMLK[136.11].L "sp|P55786|PSA_HUMAN,tr|A0A7I2V3W8|A0A7I2V3W8_HUMAN,tr|A0A7I2V389|A0A7I2V389_HUMAN,tr|E9PLK3|E9PLK3_HUMAN" 4 1307.6635 0.81 50546 16879 3 1307.665352 436.8951 Puromycin-sensitive aminopeptidase OS=Homo sapiens OX=9606 GN=NPEPPS PE=1 SV=2 5.21 2938 - 283709 - - - 1.4262 - 2.13 0.409 - 132.1 1 2 0 0.0019 12 0 0 0 1.56E+06 1.93E+06 - - - 5.1953 0.9721 221125_WJC_METTL3_EV_vs_WT_F04.16880.16880.2 0.00118 24-Oct K.QLSVVVPSYNEEK.R "sp|Q9Y673|ALG5_HUMAN,tr|A0A7P0TAL2|A0A7P0TAL2_HUMAN,tr|A0A7P0TAI2|A0A7P0TAI2_HUMAN,tr|A0A7P0TA98|A0A7P0TA98_HUMAN,tr|A0A7P0T901|A0A7P0T901_HUMAN,tr|A0A7P0T9C7|A0A7P0T9C7_HUMAN,tr|B4DR67|B4DR67_HUMAN,tr|A0A7P0Z4I2|A0A7P0Z4I2_HUMAN,tr|A0A7P0TB27|A0A7P0TB27_HUMAN,tr|A0A7P0T882|A0A7P0T882_HUMAN,tr|A0A7P0T9B8|A0A7P0T9B8_HUMAN,tr|A0A7P0T850|A0A7P0T850_HUMAN,tr|A0A7P0T9X2|A0A7P0T9X2_HUMAN" 13 1490.7617 0.94 50547 16880 2 1490.772512 746.3881 Dolichyl-phosphate beta-glucosyltransferase OS=Homo sapiens OX=9606 GN=ALG5 PE=1 SV=1 4.53 2938.2 - 270128 - - - 7.2701 - 1.872 0.369 - 277.5 1 2 0 0.0108 13 0 0 0 1.95E+06 2.07E+06 - - - 3.3723 1 221125_WJC_METTL3_EV_vs_WT_F04.16885.16885.3 3.59E-07 14/48 R.HPDVEVDGFSELR.W "sp|P09874|PARP1_HUMAN,tr|A0A7I2V384|A0A7I2V384_HUMAN,tr|A0A7I2V5E9|A0A7I2V5E9_HUMAN,tr|A0A7I2V625|A0A7I2V625_HUMAN,tr|A0A7I2V3E1|A0A7I2V3E1_HUMAN" 5 1498.7052 1.45 50550 16885 3 1498.705767 500.5757 Poly [ADP-ribose] polymerase 1 OS=Homo sapiens OX=9606 GN=PARP1 PE=1 SV=4 4.31 2938.8 - 4.14E+06 - - - 0.3636 - 2.892 0.563 - 327 1 2 0 0.0005 13 0 0 0 5.08E+07 3.50E+07 - - - 7.696 0.9999 221125_WJC_METTL3_EV_vs_WT_F04.16889.16889.3 1.79E-09 19/68 R.VEAGDVIYIEANSGAVK[136.11]R[166.11].Q "sp|Q9Y265|RUVB1_HUMAN,tr|H7C4I3|H7C4I3_HUMAN,tr|E7ETR0|E7ETR0_HUMAN" 3 1908.0072 0.49 50554 16889 3 1908.011061 637.0097 RuvB-like 1 OS=Homo sapiens OX=9606 GN=RUVBL1 PE=1 SV=1 4.68 2939.1 - 1.30E+06 - - - 2.044 - 3.409 0.45 - 442.4 1 2 0 0.0039 18 0 0 0 6.31E+06 1.30E+07 - - - 6.6099 0.9814 221125_WJC_METTL3_EV_vs_WT_F04.16890.16890.2 0.00143 14/28 K.QHGVNVSVNASATPF.Q "sp|Q14157|UBP2L_HUMAN,tr|F8W726|F8W726_HUMAN,tr|H7C2T8|H7C2T8_HUMAN,tr|H0Y5H6|H0Y5H6_HUMAN" 4 1526.7478 - 50555 16890 2 1526.749968 764.3812 Ubiquitin-associated protein 2-like OS=Homo sapiens OX=9606 GN=UBAP2L PE=1 SV=2 6.74 2939.2 - 1.10E+06 - - - 1.4495 - 2.285 0.418 - 267.8 1 1 0 0.0022 15 0 0 0 - - - - - 4.1593 0.9949 221125_WJC_METTL3_EV_vs_WT_F04.16891.16891.3 0.0378 13/44 R.DLKPQNLLINEK.G "sp|Q00537|CDK17_HUMAN,tr|F5H6Z0|F5H6Z0_HUMAN" 2 1423.8035 1.39 50556 16891 3 1423.804658 475.6084 Cyclin-dependent kinase 17 OS=Homo sapiens OX=9606 GN=CDK17 PE=1 SV=2 6.07 2939.3 - 966598 - - - 0.8281 - 2.345 0.12 - 257.2 1 2 0 0.0012 12 0 0 0 6.23E+06 4.49E+06 - - - 2.24 1 221125_WJC_METTL3_EV_vs_WT_F04.16892.16892.2 3.02E-08 14/26 K.QAAGVISLPVGGNK[136.11].D "sp|Q96T37|RBM15_HUMAN,tr|A0A494C001|A0A494C001_HUMAN,tr|A0A499FJY3|A0A499FJY3_HUMAN,tr|A0A087WWP4|A0A087WWP4_HUMAN" 4 1317.7496 1.06 50557 16892 2 1317.751492 659.8821 RNA-binding protein 15 OS=Homo sapiens OX=9606 GN=RBM15 PE=1 SV=2 8.75 2939.4 - 963580 - - - 1.4358 - 2.883 0.561 - 523.4 1 2 0 0.0019 14 0 0 0 9.04E+06 8.53E+06 - - - 5.841 0.9997 221125_WJC_METTL3_EV_vs_WT_F04.16893.16893.2 4.33E-05 20-Nov K.GK[136.11]PLALVEEIR[166.11].N "sp|Q9BSD7|NTPCR_HUMAN,tr|Q5TDF0|Q5TDF0_HUMAN" 2 1241.7462 1.19 50558 16893 2 1241.748192 621.8804 Cancer-related nucleoside-triphosphatase OS=Homo sapiens OX=9606 GN=NTPCR PE=1 SV=1 6.14 2939.6 - 927760 - - - 1.5704 - 1.967 0.445 - 458.5 1 2 0 0.0019 11 0 0 0 7.29E+06 6.13E+06 - - - 4.1573 1 221125_WJC_METTL3_EV_vs_WT_F04.16897.16897.3 9.14E-10 24/68 K.LLVDVDESTLSPEEQKER.K sp|O75533|SF3B1_HUMAN 1 2086.043 1.18 50562 16897 3 2086.04653 696.3549 Splicing factor 3B subunit 1 OS=Homo sapiens OX=9606 GN=SF3B1 PE=1 SV=3 4.08 2940 - 664954 - - - 1.6951 - 4.356 0.658 - 667.7 1 2 1 0.0035 18 0 0 0 2.13E+07 1.80E+07 - - - 9.5394 1 221125_WJC_METTL3_EV_vs_WT_F04.16899.16899.3 3.08E-06 16/52 K.NNVNVASLTQSEIR[166.11].D sp|Q6P2Q9|PRP8_HUMAN 1 1553.8037 1.47 50564 16899 3 1553.804428 518.9418 Pre-mRNA-processing-splicing factor 8 OS=Homo sapiens OX=9606 GN=PRPF8 PE=1 SV=2 6 2940.2 - 566669 - - - 0.466 - 2.686 0.477 - 349 1 2 0 0.0007 14 0 0 0 6.10E+06 4.14E+06 - - - 6.4837 0.9998 221125_WJC_METTL3_EV_vs_WT_F04.16900.16900.3 4.02E-05 14/40 K.ALNSIIDVYHK.Y sp|P05109|S10A8_HUMAN 1 1271.6874 111.29 50565 16900 3 1271.689667 424.9031 Protein S100-A8 OS=Homo sapiens OX=9606 GN=S100A8 PE=1 SV=1 6.79 2940.4 - 545699 - - - 1.7929 - 2.291 0.395 - 250.1 1 2 0 0.0023 11 0 0 0 4.74E+07 4.26E+05 - - - 5.2982 0.9999 221125_WJC_METTL3_EV_vs_WT_F04.16908.16908.3 4.81E-07 22/68 K.LLVDVDESTLSPEEQK[136.11]ER[166.11].K sp|O75533|SF3B1_HUMAN 1 2104.0655 1.2 50572 16908 3 2104.069275 702.3624 Splicing factor 3B subunit 1 OS=Homo sapiens OX=9606 GN=SF3B1 PE=1 SV=3 4.08 2941.4 - 1.62E+06 - - - 1.8113 - 3.374 0.585 - 467.4 1 2 1 0.0038 18 0 0 0 2.15E+07 1.80E+07 - - - 8.0893 1 221125_WJC_METTL3_EV_vs_WT_F04.16909.16909.2 2.52E-06 17/26 K.NNVNVASLTQSEIR[166.11].D sp|Q6P2Q9|PRP8_HUMAN 1 1553.8037 0.59 50573 16909 2 1553.804492 777.9091 Pre-mRNA-processing-splicing factor 8 OS=Homo sapiens OX=9606 GN=PRPF8 PE=1 SV=2 6 2941.5 - 1.58E+06 - - - 0.5071 - 3.403 0.604 - 1093.3 1 2 0 0.0008 14 0 0 0 5.64E+06 9.52E+06 - - - 6.5751 0.9999 221125_WJC_METTL3_EV_vs_WT_F04.16911.16911.2 1.13E-08 14/26 R.AEQWNVNYVETSAK[136.11].T "sp|P11233|RALA_HUMAN,tr|H7C3P7|H7C3P7_HUMAN" 2 1645.7828 1.69 50575 16911 2 1645.782041 823.8987 Ras-related protein Ral-A OS=Homo sapiens OX=9606 GN=RALA PE=1 SV=1 4.53 2941.8 - 622810 - - - -0.4308 - 2.844 0.503 - 788.4 1 2 0 -0.0007 14 0 0 0 1.29E+07 7.64E+06 - - - 5.3788 1 221125_WJC_METTL3_EV_vs_WT_F04.16913.16913.3 9.82E-07 17/56 R.TQVELLEAPTPALK[136.11]R[166.11].T sp|P13807|GYS1_HUMAN 1 1682.9686 1.56 50577 16913 3 1682.966681 561.9968 "Glycogen [starch] synthase, muscle OS=Homo sapiens OX=9606 GN=GYS1 PE=1 SV=2" 5.81 2942 - 555459 - - - -1.1349 - 2.795 0.452 - 462.7 1 2 0 -0.0019 15 0 0 0 6.46E+06 4.13E+06 - - - 6.2608 0.9998 221125_WJC_METTL3_EV_vs_WT_F04.16914.16914.3 9.21E-06 15/44 K.AK[136.11]GEIPEVAFMK[136.11].- "sp|Q9UBU9|NXF1_HUMAN,tr|H0YDU0|H0YDU0_HUMAN" 2 1334.7239 0.65 50578 16914 3 1334.723765 445.9152 Nuclear RNA export factor 1 OS=Homo sapiens OX=9606 GN=NXF1 PE=1 SV=1 6.19 2942.1 - 549341 - - - -0.1079 - 2.635 0.462 - 260.9 1 2 1 -0.0001 12 0 0 0 3.72E+06 5.70E+06 - - - 6.3764 1 221125_WJC_METTL3_EV_vs_WT_F04.16915.16915.3 4.42E-06 14/56 R.TQVELLEAPTPALKR.T sp|P13807|GYS1_HUMAN 1 1664.9461 1.56 50579 16915 3 1664.948171 555.9893 "Glycogen [starch] synthase, muscle OS=Homo sapiens OX=9606 GN=GYS1 PE=1 SV=2" 5.81 2942.2 - 697599 - - - 1.2313 - 2.394 0.479 - 154.2 1 2 0 0.0021 15 0 0 0 6.46E+06 4.13E+06 - - - 6.1577 1 221125_WJC_METTL3_EV_vs_WT_F04.16920.16920.2 1.39E-11 17/42 R.AGAIAPC[160.03]EVTVPAQNTGLGPEK[136.11].T "sp|Q8NHW5|RLA0L_HUMAN,sp|P05388|RLA0_HUMAN,tr|G3V210|G3V210_HUMAN,tr|F8VU65|F8VU65_HUMAN,tr|F8VWS0|F8VWS0_HUMAN,tr|F8VW21|F8VW21_HUMAN,tr|F8VRK7|F8VRK7_HUMAN,tr|F8VQY6|F8VQY6_HUMAN,tr|F8VPE8|F8VPE8_HUMAN" 9 2187.1085 1.45 50584 16920 2 2187.108081 1094.5615 60S acidic ribosomal protein P0-like OS=Homo sapiens OX=9606 GN=RPLP0P6 PE=5 SV=1 4.53 2942.9 - 424263 - - - -0.2003 - 2.865 0.692 - 451.7 1 2 0 -0.0004 22 0 0 0 2.65E+06 1.82E+06 - - - 6.7398 1 221125_WJC_METTL3_EV_vs_WT_F04.16921.16921.2 3.72E-06 15/30 R.GALQGSAWQVSSEDVR.W "sp|Q9Y4W2|LAS1L_HUMAN,tr|A0A7I2V4E5|A0A7I2V4E5_HUMAN" 2 1688.8118 0.65 50585 16921 2 1688.813488 845.4132 Ribosomal biogenesis protein LAS1L OS=Homo sapiens OX=9606 GN=LAS1L PE=1 SV=2 4.37 2943 - 414634 - - - 0.9924 - 3.207 0.604 - 757 1 2 0 0.0017 16 0 0 0 2.24E+06 3.43E+06 - - - 6.3666 0.9996 221125_WJC_METTL3_EV_vs_WT_F04.16924.16924.2 2.21E-11 16/42 R.AGAIAPC[160.03]EVTVPAQNTGLGPEK.T "sp|Q8NHW5|RLA0L_HUMAN,sp|P05388|RLA0_HUMAN,tr|G3V210|G3V210_HUMAN,tr|F8VU65|F8VU65_HUMAN,tr|F8VWS0|F8VWS0_HUMAN,tr|F8VW21|F8VW21_HUMAN,tr|F8VRK7|F8VRK7_HUMAN,tr|F8VQY6|F8VQY6_HUMAN,tr|F8VPE8|F8VPE8_HUMAN" 9 2179.0943 1.45 50588 16924 2 2179.087611 1090.5544 60S acidic ribosomal protein P0-like OS=Homo sapiens OX=9606 GN=RPLP0P6 PE=5 SV=1 4.53 2943.4 - 293488 - - - -3.0783 - 2.948 0.539 - 328.6 1 2 0 -0.0067 22 0 0 0 2.65E+06 1.82E+06 - - - 5.6779 0.9999 221125_WJC_METTL3_EV_vs_WT_F04.16929.16929.3 6.44E-06 13/44 R.FIQFEPEEDIKR.K "sp|Q9NUQ7|UFSP2_HUMAN,tr|D6RA67|D6RA67_HUMAN,tr|D6RB53|D6RB53_HUMAN,tr|D6RGX2|D6RGX2_HUMAN" 4 1549.7777 1.66 50592 16929 3 1549.780882 517.5998 Ufm1-specific protease 2 OS=Homo sapiens OX=9606 GN=UFSP2 PE=1 SV=3 4.41 2943.8 - 2.19E+06 - - - 2.0797 - 2.261 0.51 - 220.5 1 2 0 0.0032 12 0 0 0 1.43E+07 8.60E+06 - - - 6.4864 0.9999 221125_WJC_METTL3_EV_vs_WT_F04.16931.16931.2 3.28E-06 13/24 R.FSGSGSGTDFTLK.L "sp|A2NJV5|KV229_HUMAN,sp|A0A087WW87|KV240_HUMAN,sp|P06310|KV230_HUMAN,sp|A0A075B6S2|KVD29_HUMAN,sp|P01614|KVD40_HUMAN,sp|P01615|KVD28_HUMAN,sp|A0A075B6S6|KVD30_HUMAN,sp|A0A075B6P5|KV228_HUMAN,sp|A0A0A0MRZ7|KVD26_HUMAN" 9 1302.6092 123.8 50594 16931 2 1302.608832 652.3119 Immunoglobulin kappa variable 2-29 OS=Homo sapiens OX=9606 GN=IGKV2-29 PE=3 SV=2 5.84 2944 - 1.46E+06 - - - -0.2794 - 2.447 0.561 - 319.4 1 2 0 -0.0004 13 0 0 0 1.19E+07 9.65E+04 - - - 5.4811 0.9999 221125_WJC_METTL3_EV_vs_WT_F04.16937.16937.3 4.02E-07 Dec-44 K.AKGEIPEVAFMK.- "sp|Q9UBU9|NXF1_HUMAN,tr|H0YDU0|H0YDU0_HUMAN" 2 1318.6955 0.56 50600 16937 3 1318.695332 440.5724 Nuclear RNA export factor 1 OS=Homo sapiens OX=9606 GN=NXF1 PE=1 SV=1 6.19 2944.6 - 748363 - - - -0.1342 - 2.793 0.453 - 251.1 1 2 1 -0.0002 12 0 0 0 3.72E+06 6.61E+06 - - - 6.4375 0.9999 221125_WJC_METTL3_EV_vs_WT_F04.16939.16939.3 0.00346 Nov-40 R.KVDEAIALFQK.M "sp|P26640|SYVC_HUMAN,tr|A0A140T936|A0A140T936_HUMAN" 2 1260.7078 0.5 50602 16939 3 1260.708528 421.2432 Valine--tRNA ligase OS=Homo sapiens OX=9606 GN=VARS1 PE=1 SV=4 6.07 2944.8 - 597031 - - - 0.587 - 2.277 0.412 - 199.6 1 2 0 0.0007 11 0 0 0 3.12E+06 6.22E+06 - - - 5.4708 0.9999 221125_WJC_METTL3_EV_vs_WT_F04.16941.16941.3 0.000169 18/68 K.ASEQIYGTPSSSPYEC[160.03]LR.Q "sp|Q14203|DCTN1_HUMAN,tr|A0A804CDA6|A0A804CDA6_HUMAN,tr|E7EX90|E7EX90_HUMAN,tr|A0A7P0Z4C3|A0A7P0Z4C3_HUMAN" 4 2043.9208 1.68 50604 16941 3 2043.91539 682.3142 Dynactin subunit 1 OS=Homo sapiens OX=9606 GN=DCTN1 PE=1 SV=3 4.53 2945.1 - 502877 - - - -2.6327 - 3.305 0.464 - 347.5 1 2 0 -0.0054 18 0 0 0 3.52E+06 2.10E+06 - - - 6.6884 0.9999 221125_WJC_METTL3_EV_vs_WT_F04.16942.16942.2 2.20E-06 13/30 R.GALQGSAWQVSSEDVR[166.11].W "sp|Q9Y4W2|LAS1L_HUMAN,tr|A0A7I2V4E5|A0A7I2V4E5_HUMAN" 2 1698.8201 0.65 50605 16942 2 1698.820413 850.4173 Ribosomal biogenesis protein LAS1L OS=Homo sapiens OX=9606 GN=LAS1L PE=1 SV=2 4.37 2945.2 - 466392 - - - 0.1948 - 2.923 0.541 - 492.7 1 2 0 0.0003 16 0 0 0 2.24E+06 3.43E+06 - - - 5.6738 0.9581 221125_WJC_METTL3_EV_vs_WT_F04.16943.16943.3 0.000207 Sep-56 K.VEHLEEGPMIEQLSK.M "sp|Q9Y6G3|RM42_HUMAN,tr|S4R360|S4R360_HUMAN,tr|J3KPP0|J3KPP0_HUMAN,tr|S4R2Z7|S4R2Z7_HUMAN" 4 1737.8607 6.08 50606 16943 3 1738.856776 580.2942 "39S ribosomal protein L42, mitochondrial OS=Homo sapiens OX=9606 GN=MRPL42 PE=1 SV=1" 4.48 2945.3 - 418802 - - - 573.1414 - 1.753 0.448 - 62.4 1 2 0 0.996 15 0 0 0 1.29E+07 2.13E+06 - - - 4.7236 0.9999 221125_WJC_METTL3_EV_vs_WT_F04.16944.16944.3 1.42E-05 Nov-44 R.HGLEAISIMDSR.G "sp|P26640|SYVC_HUMAN,tr|A0A140T936|A0A140T936_HUMAN" 2 1327.6554 0.64 50607 16944 3 1327.657622 443.5591 Valine--tRNA ligase OS=Homo sapiens OX=9606 GN=VARS1 PE=1 SV=4 5.32 2945.4 - 412727 - - - 1.6473 - 1.73 0.478 - 163.6 1 2 0 0.0022 12 0 0 0 2.17E+06 3.38E+06 - - - 5.3879 0.9998 221125_WJC_METTL3_EV_vs_WT_F04.16948.16948.3 7.57E-06 Dec-44 R.TC[160.03]TDIKPEWLVK.L sp|O43143|DHX15_HUMAN 1 1488.7647 0.81 50610 16948 3 1488.768675 497.2622 Pre-mRNA-splicing factor ATP-dependent RNA helicase DHX15 OS=Homo sapiens OX=9606 GN=DHX15 PE=1 SV=2 5.73 2945.9 - 1.52E+06 - - - 2.7029 - 2.06 0.449 - 132.1 1 2 0 0.004 12 0 0 0 1.00E+07 1.24E+07 - - - 5.548 1 221125_WJC_METTL3_EV_vs_WT_F04.16951.16951.2 1.09E-07 13/22 K.STNEAMEWMNNK[136.11].L sp|P34932|HSP74_HUMAN 1 1461.6108 0.07 50613 16951 2 1461.608347 731.8127 Heat shock 70 kDa protein 4 OS=Homo sapiens OX=9606 GN=HSPA4 PE=1 SV=4 4.53 2946.1 - 2.27E+06 - - - -1.6776 - 2.717 0.635 - 947.4 1 2 0 -0.0025 12 0 0 0 1.34E+06 2.05E+07 - - - 6.3603 1 221125_WJC_METTL3_EV_vs_WT_F04.16952.16952.3 2.56E-08 14/44 R.TC[160.03]TDIK[136.11]PEWLVK[136.11].L sp|O43143|DHX15_HUMAN 1 1504.7931 1.02 50614 16952 3 1504.794256 502.605 Pre-mRNA-splicing factor ATP-dependent RNA helicase DHX15 OS=Homo sapiens OX=9606 GN=DHX15 PE=1 SV=2 5.73 2946.2 - 1.75E+06 - - - 0.8008 - 2.435 0.614 - 210.5 1 2 0 0.0012 12 0 0 0 1.40E+07 1.36E+07 - - - 7.852 1 221125_WJC_METTL3_EV_vs_WT_F04.16954.16954.2 5.27E-08 15/26 R.AEQWNVNYVETSAK.T "sp|P11233|RALA_HUMAN,tr|H7C3P7|H7C3P7_HUMAN" 2 1637.7686 1.65 50616 16954 2 1637.769734 819.8916 Ras-related protein Ral-A OS=Homo sapiens OX=9606 GN=RALA PE=1 SV=1 4.53 2946.3 - 1.33E+06 - - - 0.7229 - 2.921 0.549 - 1121.1 1 2 0 0.0012 14 0 0 0 1.26E+07 7.64E+06 - - - 5.7855 1 221125_WJC_METTL3_EV_vs_WT_F04.16957.16957.4 8.59E-06 23/96 K.IFASIAPSIYGHEDIK[136.11]R[166.11].G "sp|P49736|MCM2_HUMAN,tr|H0Y8E6|H0Y8E6_HUMAN" 2 1934.0381 1.17 50619 16957 4 1934.040707 484.5168 DNA replication licensing factor MCM2 OS=Homo sapiens OX=9606 GN=MCM2 PE=1 SV=4 6.75 2946.7 - 729759 - - - 1.3645 - 4.357 0.492 - 691 1 2 0 0.0026 17 0 0 0 3.11E+06 2.66E+06 - - - 4.0186 1 221125_WJC_METTL3_EV_vs_WT_F04.16958.16958.2 7.39E-09 15/28 R.AFEVSENGNLVVSGK[136.11].V "sp|P49327|FAS_HUMAN,tr|A0A0U1RQF0|A0A0U1RQF0_HUMAN" 2 1556.7926 0.71 50620 16958 2 1556.789774 779.4036 Fatty acid synthase OS=Homo sapiens OX=9606 GN=FASN PE=1 SV=3 4.53 2946.8 - 556634 - - - -1.8069 - 3.011 0.674 - 561.1 1 2 0 -0.0028 15 0 0 0 9.20E+06 1.30E+07 - - - 6.7283 0.9961 221125_WJC_METTL3_EV_vs_WT_F04.16959.16959.2 3.68E-05 13/30 K.APPPSLTDC[160.03]IGTVDSR.A sp|Q9NZZ3|CHMP5_HUMAN 1 1684.809 -1 50621 16959 2 1684.799522 843.4118 Charged multivesicular body protein 5 OS=Homo sapiens OX=9606 GN=CHMP5 PE=1 SV=1 4.21 2946.9 - 539070 - - - -5.6463 - 2.222 0.507 - 446.1 1 2 0 -0.0095 16 0 0 0 0.00E+00 0.00E+00 - - - 4.7456 1 221125_WJC_METTL3_EV_vs_WT_F04.16960.16960.3 9.34E-05 15/68 K.ASEQIYGTPSSSPYEC[160.03]LR[166.11].Q "sp|Q14203|DCTN1_HUMAN,tr|A0A804CDA6|A0A804CDA6_HUMAN,tr|E7EX90|E7EX90_HUMAN,tr|A0A7P0Z4C3|A0A7P0Z4C3_HUMAN" 4 2053.929 1.68 50622 16960 3 2053.931574 685.6503 Dynactin subunit 1 OS=Homo sapiens OX=9606 GN=DCTN1 PE=1 SV=3 4.53 2947.1 - 511502 - - - 1.2332 - 2.847 0.45 - 225.1 1 2 0 0.0025 18 0 0 0 3.52E+06 2.10E+06 - - - 6.1617 0.9986 221125_WJC_METTL3_EV_vs_WT_F04.16961.16961.3 0.00183 Nov-36 K.QFVFDLHSGK[136.11].L sp|Q9BS26|ERP44_HUMAN 1 1184.607 0.9 50623 16961 3 1184.606771 395.8763 Endoplasmic reticulum resident protein 44 OS=Homo sapiens OX=9606 GN=ERP44 PE=1 SV=1 6.74 2947.2 - 481021 - - - -0.1579 - 2.106 0.213 - 151 1 2 0 -0.0002 10 0 0 0 3.26E+06 3.62E+06 - - - 3.0898 1 221125_WJC_METTL3_EV_vs_WT_F04.16962.16962.2 1.46E-06 17/34 K.ASEQIYGTPSSSPYEC[160.03]LR.Q "sp|Q14203|DCTN1_HUMAN,tr|A0A804CDA6|A0A804CDA6_HUMAN,tr|E7EX90|E7EX90_HUMAN,tr|A0A7P0Z4C3|A0A7P0Z4C3_HUMAN" 4 2043.9208 2.28 50624 16962 2 2043.917891 1022.9677 Dynactin subunit 1 OS=Homo sapiens OX=9606 GN=DCTN1 PE=1 SV=3 4.53 2947.4 - 463087 - - - -1.4091 - 3.413 0.641 - 552.8 1 2 0 -0.0029 18 0 0 0 3.17E+06 1.39E+06 - - - 6.7926 0.9995 221125_WJC_METTL3_EV_vs_WT_F04.16963.16963.3 0.00132 Nov-40 R.LAYKDLEIQMK.K "sp|Q9NP61|ARFG3_HUMAN,tr|H0Y6A0|H0Y6A0_HUMAN" 2 1350.7217 1.23 50625 16963 3 1350.723976 451.2479 ADP-ribosylation factor GTPase-activating protein 3 OS=Homo sapiens OX=9606 GN=ARFGAP3 PE=1 SV=1 6.07 2947.5 - 340684 - - - 1.6673 - 2.173 0.434 - 164.6 1 2 1 0.0023 11 0 0 0 1.85E+06 1.50E+06 - - - 5.5828 1 221125_WJC_METTL3_EV_vs_WT_F04.16965.16965.2 1.27E-08 17/30 K.VTADVTSAVMGNPVTR.E "sp|Q6P3W7|SCYL2_HUMAN,tr|F8VSC5|F8VSC5_HUMAN,tr|A0A0U1RQQ9|A0A0U1RQQ9_HUMAN" 3 1616.8192 1.55 50627 16965 2 1616.82366 809.4169 SCY1-like protein 2 OS=Homo sapiens OX=9606 GN=SCYL2 PE=1 SV=1 5.81 2947.7 - 252831 - - - 2.7548 - 3.544 0.604 - 915 1 2 0 0.0045 16 0 0 0 2.70E+06 1.75E+06 - - - 6.6114 1 221125_WJC_METTL3_EV_vs_WT_F04.16969.16969.3 9.19E-06 16/52 K.TLAEHQQLIPLVEK[136.11].A "sp|Q9Y5K5|UCHL5_HUMAN,tr|H0Y4K0|H0Y4K0_HUMAN,tr|H0Y4E0|H0Y4E0_HUMAN,tr|Q5LJA9|Q5LJA9_HUMAN,tr|H0Y636|H0Y636_HUMAN,tr|H0Y6Y4|H0Y6Y4_HUMAN,tr|Q5LJA5|Q5LJA5_HUMAN" 7 1625.9232 1.72 50629 16969 3 1625.923714 542.9817 Ubiquitin carboxyl-terminal hydrolase isozyme L5 OS=Homo sapiens OX=9606 GN=UCHL5 PE=1 SV=3 5.37 2948.2 - 2.85E+06 - - - 0.3118 - 2.658 0.524 - 211.2 1 2 0 0.0005 14 0 0 0 8.07E+07 4.70E+07 - - - 6.9799 0.9993 221125_WJC_METTL3_EV_vs_WT_F04.16970.16970.2 1.1 16-Dec R.R[166.11]LNVWDLSK[136.11].L "sp|Q09028|RBBP4_HUMAN,sp|Q16576|RBBP7_HUMAN,tr|H0YCT5|H0YCT5_HUMAN,tr|H0YDK2|H0YDK2_HUMAN,tr|Q5JP02|Q5JP02_HUMAN,tr|H0YEU5|H0YEU5_HUMAN,tr|H0YF10|H0YF10_HUMAN,tr|E9PC52|E9PC52_HUMAN" 8 1147.6469 1.39 50630 16970 2 1147.647388 574.8307 Histone-binding protein RBBP4 OS=Homo sapiens OX=9606 GN=RBBP4 PE=1 SV=3 8.75 2948.3 - 2.44E+06 - - - 0.4575 - 2.383 0.159 - 605.1 1 2 0 0.0005 9 0 0 0 2.30E+07 1.65E+07 - - - 2.7274 0.9998 221125_WJC_METTL3_EV_vs_WT_F04.16973.16973.3 0.00372 Oct-44 R.FIQFEPEEDIK[136.11]R[166.11].K "sp|Q9NUQ7|UFSP2_HUMAN,tr|D6RA67|D6RA67_HUMAN,tr|D6RB53|D6RB53_HUMAN,tr|D6RGX2|D6RGX2_HUMAN" 4 1567.8001 1.72 50633 16973 3 1567.798235 523.6073 Ufm1-specific protease 2 OS=Homo sapiens OX=9606 GN=UFSP2 PE=1 SV=3 4.41 2948.5 - 1.22E+06 - - - -1.2081 - 2.069 0.375 - 111.1 1 2 0 -0.0019 12 0 0 0 1.49E+07 8.67E+06 - - - 4.7357 0.9999 221125_WJC_METTL3_EV_vs_WT_F04.16974.16974.3 2.48E-07 14/44 R.SILK[136.11]IDDVVNTR[166.11].- sp|P50991|TCPD_HUMAN 1 1389.7946 0.22 50634 16974 3 1389.796257 464.2722 T-complex protein 1 subunit delta OS=Homo sapiens OX=9606 GN=CCT4 PE=1 SV=4 5.68 2948.6 - 1.01E+06 - - - 1.157 - 2.766 0.52 - 268.5 1 2 1 0.0016 12 0 0 0 1.30E+06 5.88E+06 - - - 7.1571 0.9995 221125_WJC_METTL3_EV_vs_WT_F04.16976.16976.2 5.30E-08 13/28 R.AFEVSENGNLVVSGK.V "sp|P49327|FAS_HUMAN,tr|A0A0U1RQF0|A0A0U1RQF0_HUMAN" 2 1548.7784 0.71 50636 16976 2 1548.783288 775.3965 Fatty acid synthase OS=Homo sapiens OX=9606 GN=FASN PE=1 SV=3 4.53 2948.7 - 955403 - - - 3.1644 - 2.821 0.489 - 540.6 1 2 0 0.0049 15 0 0 0 8.96E+06 1.27E+07 - - - 5.201 1 221125_WJC_METTL3_EV_vs_WT_F04.16977.16977.3 4.75E-05 20/68 R.LSSPC[160.03]IMVVNHDASSIPR.L sp|Q08J23|NSUN2_HUMAN 1 1981.9714 1.11 50637 16977 3 1981.971417 661.6644 RNA cytosine C(5)-methyltransferase NSUN2 OS=Homo sapiens OX=9606 GN=NSUN2 PE=1 SV=2 6.74 2948.8 - 940879 - - - 0.0252 - 3.762 0.507 - 548.4 1 2 0 0.0001 18 0 0 0 7.98E+06 7.21E+06 - - - 7.4918 0.9994 221125_WJC_METTL3_EV_vs_WT_F04.16978.16978.3 0.000684 Sep-48 R.YLADLPTLEDHQK.Q "sp|Q6P2H3|CEP85_HUMAN,tr|H7BZW2|H7BZW2_HUMAN" 2 1541.7726 0.32 50638 16978 3 1541.773218 514.9315 Centrosomal protein of 85 kDa OS=Homo sapiens OX=9606 GN=CEP85 PE=1 SV=1 4.54 2948.9 - 910671 - - - 0.4183 - 1.964 0.303 - 59.7 1 2 0 0.0006 13 0 0 0 4.45E+06 1.41E+07 - - - 3.748 0.9995 221125_WJC_METTL3_EV_vs_WT_F04.16979.16979.3 0.00528 Oct-32 R.EHVYDLFEK.A "sp|Q15020|SART3_HUMAN,tr|F8VVK9|F8VVK9_HUMAN,tr|A0A494C0L2|A0A494C0L2_HUMAN,tr|F8W667|F8W667_HUMAN,tr|A0A499FI31|A0A499FI31_HUMAN,tr|F8VZM2|F8VZM2_HUMAN" 6 1178.5608 2.8 50639 16979 3 1178.560178 393.8609 Squamous cell carcinoma antigen recognized by T-cells 3 OS=Homo sapiens OX=9606 GN=SART3 PE=1 SV=1 4.65 2949 - 816043 - - - -0.5184 - 1.808 0.316 - 163.4 1 2 0 -0.0006 9 0 0 0 3.54E+06 1.27E+06 - - - 3.8478 0.9904 221125_WJC_METTL3_EV_vs_WT_F04.16981.16981.3 0.341 Aug-36 K.ELHINLIPNK[136.11].Q "sp|P07900|HS90A_HUMAN,sp|Q14568|HS902_HUMAN,tr|G3V2J8|G3V2J8_HUMAN" 3 1197.6961 0.64 50641 16981 3 1197.695002 400.2393 Heat shock protein HSP 90-alpha OS=Homo sapiens OX=9606 GN=HSP90AA1 PE=1 SV=5 6.85 2949.3 - 633903 - - - -0.9234 - 1.5 0.189 - 77.8 1 2 0 -0.0011 10 0 0 0 9.46E+06 1.47E+07 - - - 1.831 1 221125_WJC_METTL3_EV_vs_WT_F04.16985.16985.2 1.64E-08 13/30 R.AFNSVDPTFDNSVPSK[136.11].S "sp|Q99543|DNJC2_HUMAN,tr|C9IZ83|C9IZ83_HUMAN,tr|H7C3L7|H7C3L7_HUMAN" 3 1731.8195 0.73 50645 16985 2 1731.818254 866.917 DnaJ homolog subfamily C member 2 OS=Homo sapiens OX=9606 GN=DNAJC2 PE=1 SV=4 4.21 2949.8 - 467581 - - - -0.7368 - 2.725 0.612 - 387.2 1 2 0 -0.0013 16 0 0 0 3.62E+06 4.95E+06 - - - 6.0254 0.9997 221125_WJC_METTL3_EV_vs_WT_F04.16986.16986.3 5.90E-05 Dec-52 R.SWTAADTAAQITQR[166.11].K "sp|P01889|HLAB_HUMAN,sp|P10321|HLAC_HUMAN,tr|A0A140TA02|A0A140TA02_HUMAN,tr|A0A140T953|A0A140T953_HUMAN,tr|A0A1W2PP77|A0A1W2PP77_HUMAN,tr|A0A140T921|A0A140T921_HUMAN,tr|A0A1W2PNZ7|A0A1W2PNZ7_HUMAN,tr|A0A140T942|A0A140T942_HUMAN,tr|A0A140T951|A0A140T951_HUMAN,tr|A0A140TA05|A0A140TA05_HUMAN,tr|O19617|O19617_HUMAN,tr|Q53YP1|Q53YP1_HUMAN,tr|A0A140T997|A0A140T997_HUMAN,tr|Q2L6G2|Q2L6G2_HUMAN,tr|A0A1W2PRZ0|A0A1W2PRZ0_HUMAN,tr|A0A140T9E1|A0A140T9E1_HUMAN,tr|A0A140T9U0|A0A140T9U0_HUMAN,tr|F6U0H7|F6U0H7_HUMAN,tr|A0A140TA14|A0A140TA14_HUMAN,tr|A0A1W2PNR7|A0A1W2PNR7_HUMAN,tr|A0A140TA11|A0A140TA11_HUMAN,tr|A0A140T9W2|A0A140T9W2_HUMAN,tr|O78179|O78179_HUMAN,tr|D5H3J5|D5H3J5_HUMAN,tr|S6AU73|S6AU73_HUMAN,tr|A2AEA2|A2AEA2_HUMAN,tr|A0A140T9T1|A0A140T9T1_HUMAN,tr|A0A140T9Y5|A0A140T9Y5_HUMAN,tr|A0A140TA13|A0A140TA13_HUMAN,tr|A0A140T9H5|A0A140T9H5_HUMAN,tr|Q5QT33|Q5QT33_HUMAN,tr|A0A140T9J9|A0A140T9J9_HUMAN,tr|A0A140T9L3|A0A140T9L3_HUMAN,tr|A0A140T9G0|A0A140T9G0_HUMAN,tr|A0A140T9H3|A0A140T9H3_HUMAN,tr|A0A140T9B3|A0A140T9B3_HUMAN,tr|Q5SS57|Q5SS57_HUMAN,tr|D9J307|D9J307_HUMAN,tr|A0A140TA21|A0A140TA21_HUMAN,tr|A0A1W2PRX1|A0A1W2PRX1_HUMAN,tr|A0A140T9A9|A0A140T9A9_HUMAN,tr|A0A140T9D4|A0A140T9D4_HUMAN,tr|A0A140T937|A0A140T937_HUMAN,tr|A0A140T912|A0A140T912_HUMAN,tr|A0A140T962|A0A140T962_HUMAN,tr|A0A140T9M0|A0A140T9M0_HUMAN,tr|A0A140T9S9|A0A140T9S9_HUMAN,tr|A0A140T9U8|A0A140T9U8_HUMAN,tr|A0A1W2PR11|A0A1W2PR11_HUMAN,tr|A0A140T9M5|A0A140T9M5_HUMAN,tr|A0A140T930|A0A140T930_HUMAN" 51 1528.7509 0.6 50646 16986 3 1528.746729 510.5909 "HLA class I histocompatibility antigen, B alpha chain OS=Homo sapiens OX=9606 GN=HLA-B PE=1 SV=3" 5.55 2949.9 - 441262 - - - -2.7545 - 2.216 0.41 - 142.2 1 2 0 -0.0042 14 0 0 0 1.07E+06 1.78E+06 - - - 5.2245 0.9892 221125_WJC_METTL3_EV_vs_WT_F04.16988.16988.2 1.67E-07 15/26 K.SVFPEQANNNEWAR[166.11].Y sp|O43242|PSMD3_HUMAN 1 1670.7677 0.04 50648 16988 2 1671.767065 836.3911 26S proteasome non-ATPase regulatory subunit 3 OS=Homo sapiens OX=9606 GN=PSMD3 PE=1 SV=2 4.53 2950.2 - 394417 - - - 598.1753 - 2.672 0.56 - 678 1 2 0 0.9994 14 0 0 0 2.81E+05 7.75E+06 - - - 5.3297 1 221125_WJC_METTL3_EV_vs_WT_F04.16990.16990.3 8.66E-08 16/72 K.NLPPSGAVPVTGIPPHVVK[136.11].V "sp|Q13283|G3BP1_HUMAN,tr|A0A7I2V5M7|A0A7I2V5M7_HUMAN,tr|A0A7I2YQM1|A0A7I2YQM1_HUMAN,tr|A0A7P0P2U7|A0A7P0P2U7_HUMAN,tr|A0A7I2YQU8|A0A7I2YQU8_HUMAN,tr|A0A7I2V548|A0A7I2V548_HUMAN,tr|A0A7I2V651|A0A7I2V651_HUMAN,tr|A0A7I2V4D8|A0A7I2V4D8_HUMAN,tr|A0A7I2YQN9|A0A7I2YQN9_HUMAN" 9 1886.0869 1.21 50649 16990 3 1886.087403 629.7029 Ras GTPase-activating protein-binding protein 1 OS=Homo sapiens OX=9606 GN=G3BP1 PE=1 SV=1 8.76 2950.5 - 1.98E+06 - - - 0.2571 - 2.145 0.578 - 223.9 1 2 0 0.0005 19 0 0 0 1.37E+07 1.13E+07 - - - 6.8589 0.9997 221125_WJC_METTL3_EV_vs_WT_F04.16992.16992.2 0.588 16-Nov R.RLNVWDLSK.L "sp|Q09028|RBBP4_HUMAN,sp|Q16576|RBBP7_HUMAN,tr|H0YCT5|H0YCT5_HUMAN,tr|H0YDK2|H0YDK2_HUMAN,tr|Q5JP02|Q5JP02_HUMAN,tr|H0YEU5|H0YEU5_HUMAN,tr|H0YF10|H0YF10_HUMAN,tr|E9PC52|E9PC52_HUMAN" 8 1129.6244 1.39 50651 16992 2 1129.624081 565.8195 Histone-binding protein RBBP4 OS=Homo sapiens OX=9606 GN=RBBP4 PE=1 SV=3 8.75 2950.6 - 4.98E+06 - - - -0.2762 - 2.306 0.29 - 504.2 1 2 0 -0.0003 9 0 0 0 2.30E+07 1.65E+07 - - - 3.6 1 221125_WJC_METTL3_EV_vs_WT_F04.16994.16994.2 1.98E-06 15/24 M.NIQLVTSQIDAQR[166.11].R "sp|Q86V81|THOC4_HUMAN,tr|E9PB61|E9PB61_HUMAN" 2 1494.803 0.7 50653 16994 2 1494.802091 748.4088 THO complex subunit 4 OS=Homo sapiens OX=9606 GN=ALYREF PE=1 SV=3 5.84 2950.8 - 1.71E+06 - - - -0.5921 - 2.968 0.559 - 991 1 1 0 -0.0009 13 0 0 0 3.77E+07 5.40E+07 - - - 5.9616 0.9999 221125_WJC_METTL3_EV_vs_WT_F04.16995.16995.3 0.000595 Sep-32 R.R[166.11]LNVWDLSK[136.11].L "sp|Q09028|RBBP4_HUMAN,sp|Q16576|RBBP7_HUMAN,tr|H0YCT5|H0YCT5_HUMAN,tr|H0YDK2|H0YDK2_HUMAN,tr|Q5JP02|Q5JP02_HUMAN,tr|H0YEU5|H0YEU5_HUMAN,tr|H0YF10|H0YF10_HUMAN,tr|E9PC52|E9PC52_HUMAN" 8 1147.6469 0.001 50654 16995 3 1147.645557 383.5562 Histone-binding protein RBBP4 OS=Homo sapiens OX=9606 GN=RBBP4 PE=1 SV=3 8.75 2950.9 - 1.66E+06 - - - -1.138 - 1.701 0.462 - 152.3 1 2 0 -0.0013 9 0 0 0 0.00E+00 7.52E+06 - - - 5.2915 0.9939 221125_WJC_METTL3_EV_vs_WT_F04.16996.16996.2 0.00187 15/24 M.NIQLVTSQIDAQR.R "sp|Q86V81|THOC4_HUMAN,tr|E9PB61|E9PB61_HUMAN" 2 1484.7947 0.7 50655 16996 2 1484.793306 743.4046 THO complex subunit 4 OS=Homo sapiens OX=9606 GN=ALYREF PE=1 SV=3 5.84 2951 - 1.12E+06 - - - -0.9429 - 3.014 0.494 - 998.3 1 1 0 -0.0014 13 0 0 0 3.77E+07 5.40E+07 - - - 5.5208 1 221125_WJC_METTL3_EV_vs_WT_F04.16997.16997.2 6.65E-08 14/26 R.IAEFTTNLTEEEEK.S sp|P35579|MYH9_HUMAN 1 1652.7781 0.94 50656 16997 2 1652.778228 827.3963 Myosin-9 OS=Homo sapiens OX=9606 GN=MYH9 PE=1 SV=4 3.98 2951.1 - 1.06E+06 - - - 0.0702 - 2.971 0.541 - 627.8 1 2 0 0.0001 14 0 0 0 8.70E+06 9.22E+06 - - - 5.7693 0.9998 221125_WJC_METTL3_EV_vs_WT_F04.16998.16998.3 0.00123 14/44 R.QQVLPLDSIYK[136.11]K[136.11].T "sp|A6NHR9|SMHD1_HUMAN,tr|A0A2R8YCU7|A0A2R8YCU7_HUMAN,tr|J3KTL8|J3KTL8_HUMAN" 3 1446.8417 1.25 50657 16998 3 1446.841284 483.2878 Structural maintenance of chromosomes flexible hinge domain-containing protein 1 OS=Homo sapiens OX=9606 GN=SMCHD1 PE=1 SV=2 8.5 2951.2 - 1.01E+06 - - - -0.2986 - 2.155 0.339 - 204.3 1 2 0 -0.0004 12 0 0 0 5.55E+06 4.44E+06 - - - 4.4476 0.9999 221125_WJC_METTL3_EV_vs_WT_F04.16999.16999.3 0.00135 14/44 R.QQVLPLDSIYKK.T "sp|A6NHR9|SMHD1_HUMAN,tr|A0A2R8YCU7|A0A2R8YCU7_HUMAN,tr|J3KTL8|J3KTL8_HUMAN" 3 1430.8133 1.23 50658 16999 3 1430.814069 477.945 Structural maintenance of chromosomes flexible hinge domain-containing protein 1 OS=Homo sapiens OX=9606 GN=SMCHD1 PE=1 SV=2 8.5 2951.3 - 994184 - - - 0.5263 - 2.315 0.37 - 376.9 1 2 0 0.0008 12 0 0 0 5.55E+06 4.52E+06 - - - 4.9916 0.9999 221125_WJC_METTL3_EV_vs_WT_F04.17000.17000.2 1.52E-05 15/26 R.IAEFTTNLTEEEEK[136.11].S sp|P35579|MYH9_HUMAN 1 1660.7923 0.94 50659 17000 2 1660.791794 831.4034 Myosin-9 OS=Homo sapiens OX=9606 GN=MYH9 PE=1 SV=4 3.98 2951.4 - 985814 - - - -0.3119 - 3.029 0.457 - 788.4 1 2 0 -0.0005 14 0 0 0 8.70E+06 9.22E+06 - - - 5.1973 0.9999 221125_WJC_METTL3_EV_vs_WT_F04.17007.17007.2 1.33E-06 30-Nov R.AFNSVDPTFDNSVPSK.S "sp|Q99543|DNJC2_HUMAN,tr|C9IZ83|C9IZ83_HUMAN,tr|H7C3L7|H7C3L7_HUMAN" 3 1723.8053 0.73 50666 17007 2 1723.805914 862.9099 DnaJ homolog subfamily C member 2 OS=Homo sapiens OX=9606 GN=DNAJC2 PE=1 SV=4 4.21 2952.3 - 518463 - - - 0.3388 - 2.29 0.559 - 265.8 1 2 0 0.0006 16 0 0 0 3.31E+06 4.52E+06 - - - 5.2066 1 221125_WJC_METTL3_EV_vs_WT_F04.17008.17008.2 1.41E-08 18/26 K.TLAEHQQLIPLVEK.A "sp|Q9Y5K5|UCHL5_HUMAN,tr|H0Y4K0|H0Y4K0_HUMAN,tr|H0Y4E0|H0Y4E0_HUMAN,tr|Q5LJA9|Q5LJA9_HUMAN,tr|H0Y636|H0Y636_HUMAN,tr|H0Y6Y4|H0Y6Y4_HUMAN,tr|Q5LJA5|Q5LJA5_HUMAN" 7 1617.909 1.58 50667 17008 2 1617.90457 809.9618 Ubiquitin carboxyl-terminal hydrolase isozyme L5 OS=Homo sapiens OX=9606 GN=UCHL5 PE=1 SV=3 5.37 2952.4 - 517264 - - - -2.7424 - 3.226 0.604 - 1149.8 1 2 0 -0.0044 14 0 0 0 3.98E+06 2.52E+06 - - - 6.4399 0.9999 221125_WJC_METTL3_EV_vs_WT_F04.17011.17011.2 6.70E-05 13/22 R.TVIIEQSWGSPK.V "sp|P10809|CH60_HUMAN,tr|C9JL25|C9JL25_HUMAN,tr|A0A7I2V2X6|A0A7I2V2X6_HUMAN,tr|A0A7I2YQK6|A0A7I2YQK6_HUMAN,tr|A0A7I2V599|A0A7I2V599_HUMAN,tr|E7EXB4|E7EXB4_HUMAN,tr|C9JL19|C9JL19_HUMAN,tr|A0A7I2YQ71|A0A7I2YQ71_HUMAN,tr|E7ESH4|E7ESH4_HUMAN,tr|A0A7I2V5M1|A0A7I2V5M1_HUMAN,tr|A0A7I2V5K3|A0A7I2V5K3_HUMAN,tr|A0A7I2V369|A0A7I2V369_HUMAN,tr|C9JCQ4|C9JCQ4_HUMAN" 13 1343.7085 1.24 50669 17011 2 1343.707807 672.8615 "60 kDa heat shock protein, mitochondrial OS=Homo sapiens OX=9606 GN=HSPD1 PE=1 SV=2" 5.66 2952.8 - 9.23E+06 - - - -0.5276 - 2.724 0.504 - 571.6 1 2 0 -0.0007 12 0 0 0 9.49E+07 7.66E+07 - - - 5.4 0.9999 221125_WJC_METTL3_EV_vs_WT_F04.17013.17013.2 3.49E-07 14/38 R.AAALAAAVAQDPAASGAPSS.- sp|Q8TAE8|G45IP_HUMAN 1 1695.8428 - 50671 17013 2 1695.842118 848.9287 Growth arrest and DNA damage-inducible proteins-interacting protein 1 OS=Homo sapiens OX=9606 GN=GADD45GIP1 PE=1 SV=1 3.8 2952.9 - 3.40E+06 - - - -0.3892 - 2.316 0.587 - 286.1 1 2 0 -0.0007 20 0 0 0 - - - - - 5.4412 1 221125_WJC_METTL3_EV_vs_WT_F04.17015.17015.3 1.86E-10 19/60 K.LGC[160.03]INAEYPDSFGHYR.E sp|Q10469|MGAT2_HUMAN 1 1897.8417 1.47 50673 17015 3 1897.841456 633.6212 "Alpha-1,6-mannosyl-glycoprotein 2-beta-N-acetylglucosaminyltransferase OS=Homo sapiens OX=9606 GN=MGAT2 PE=1 SV=1" 5.32 2953.1 - 2.78E+06 - - - -0.146 - 3.454 0.682 - 463.5 1 2 0 -0.0003 16 0 0 0 2.09E+07 1.42E+07 - - - 9.324 0.9965 221125_WJC_METTL3_EV_vs_WT_F04.17016.17016.3 5.63E-06 15/52 R.EFTQGVK[136.11]PDWTIAR[166.11].L sp|Q8WWC4|MAIP1_HUMAN 1 1664.8641 1.17 50674 17016 3 1664.880604 555.962 "m-AAA protease-interacting protein 1, mitochondrial OS=Homo sapiens OX=9606 GN=MAIP1 PE=1 SV=1" 6.17 2953.1 - 1.85E+06 - - - 9.8975 - 2.174 0.515 - 163.1 1 2 0 0.0165 14 0 0 0 3.36E+06 2.88E+06 - - - 6.3409 0.8062 221125_WJC_METTL3_EV_vs_WT_F04.17019.17019.3 0.0491 Nov-52 K.TFNQVEIK[136.11]PEMIGH.Y "sp|P62841|RS15_HUMAN,tr|K7EM56|K7EM56_HUMAN,tr|A0A0B4J2B4|A0A0B4J2B4_HUMAN,tr|K7ELC2|K7ELC2_HUMAN,tr|S4R417|S4R417_HUMAN" 5 1649.8327 5.2 50677 17019 3 1649.832473 550.9515 40S ribosomal protein S15 OS=Homo sapiens OX=9606 GN=RPS15 PE=1 SV=2 5.37 2953.4 - 1.02E+06 - - - -0.1243 - 1.916 0.222 - 99.3 1 1 0 -0.0002 14 0 0 0 1.31E+08 2.52E+07 - - - 2.7431 0.9999 221125_WJC_METTL3_EV_vs_WT_F04.17024.17024.2 9.35E-08 15/26 R.ESATADAGYAILEK.K sp|P98175|RBM10_HUMAN 1 1437.6987 4.14 50682 17024 2 1437.697643 719.8566 RNA-binding protein 10 OS=Homo sapiens OX=9606 GN=RBM10 PE=1 SV=3 4.14 2954 - 631769 - - - -0.763 - 2.83 0.55 - 802 1 2 0 -0.0011 14 0 0 0 3.84E+06 9.29E+05 - - - 5.7135 1 221125_WJC_METTL3_EV_vs_WT_F04.17025.17025.2 2.22E-08 15/28 R.VTFEADENENITVVK[136.11].G "sp|Q9NX63|MIC19_HUMAN,tr|F8WAR4|F8WAR4_HUMAN,tr|C9JRZ6|C9JRZ6_HUMAN" 3 1714.8505 2.34 50683 17025 2 1714.850079 858.4325 MICOS complex subunit MIC19 OS=Homo sapiens OX=9606 GN=CHCHD3 PE=1 SV=1 4 2954.2 - 579065 - - - -0.2432 - 3.06 0.597 - 607.3 1 2 0 -0.0004 15 0 0 0 1.67E+07 7.13E+06 - - - 6.2 1 221125_WJC_METTL3_EV_vs_WT_F04.17026.17026.2 1.30E-09 13/26 K.C[160.03]SADSLLETNEISR.A "sp|Q5VWN6|TASO2_HUMAN,tr|A0A2R8YH03|A0A2R8YH03_HUMAN" 2 1593.7305 1.46 50684 17026 2 1593.730157 797.8725 Protein TASOR 2 OS=Homo sapiens OX=9606 GN=TASOR2 PE=1 SV=1 4.14 2954.3 - 453337 - - - -0.1845 - 3.084 0.65 - 710.1 1 2 0 -0.0003 14 0 0 0 1.96E+06 1.34E+06 - - - 6.668 0.9985 221125_WJC_METTL3_EV_vs_WT_F04.17029.17029.3 0.00307 Aug-36 R.RGDLPFVVPR.R sp|P35579|MYH9_HUMAN 1 1154.656 1.06 50687 17029 3 1154.654955 385.8926 Myosin-9 OS=Homo sapiens OX=9606 GN=MYH9 PE=1 SV=4 9.6 2954.7 - 274892 - - - -0.9284 - 1.626 0.276 - 96.4 1 2 0 -0.0011 10 0 0 0 4.59E+06 4.33E+06 - - - 3.0365 1 221125_WJC_METTL3_EV_vs_WT_F04.17033.17033.3 6.18E-08 18/60 K.LGC[160.03]INAEYPDSFGHYR[166.11].E sp|Q10469|MGAT2_HUMAN 1 1907.85 1.47 50690 17033 3 1907.848947 636.9573 "Alpha-1,6-mannosyl-glycoprotein 2-beta-N-acetylglucosaminyltransferase OS=Homo sapiens OX=9606 GN=MGAT2 PE=1 SV=1" 5.32 2955 - 4.31E+06 - - - -0.5535 - 3.254 0.636 - 418.4 1 2 0 -0.0011 16 0 0 0 2.09E+07 1.42E+07 - - - 8.6579 1 221125_WJC_METTL3_EV_vs_WT_F04.17034.17034.3 3.06E-06 17/52 K.DYGVYLEDSGHTLR[166.11].G "sp|Q13162|PRDX4_HUMAN,tr|H7C3T4|H7C3T4_HUMAN" 2 1633.7612 0.77 50691 17034 3 1633.76052 545.5943 Peroxiredoxin-4 OS=Homo sapiens OX=9606 GN=PRDX4 PE=1 SV=1 4.54 2955.1 - 3.27E+06 - - - -0.3979 - 2.256 0.601 - 283.8 1 2 0 -0.0006 14 0 0 0 3.54E+07 4.63E+07 - - - 7.4025 1 221125_WJC_METTL3_EV_vs_WT_F04.17037.17037.3 8.85E-11 16/64 R.TYADYESVNEC[160.03]MEGVC[160.03]K.M "sp|P84090|ERH_HUMAN,tr|G3V279|G3V279_HUMAN" 2 2053.8067 1.98 50694 17037 3 2053.80723 685.6095 Enhancer of rudimentary homolog OS=Homo sapiens OX=9606 GN=ERH PE=1 SV=1 4 2955.4 - 1.09E+06 - - - 0.2439 - 2.939 0.743 - 288.3 1 2 0 0.0005 17 0 0 0 2.77E+07 1.40E+07 - - - 9.5471 1 221125_WJC_METTL3_EV_vs_WT_F04.17038.17038.3 2.36E-06 18/64 K.HIVLSGGSTMYPGLPSR.L "sp|P61160|ARP2_HUMAN,tr|F5H6T1|F5H6T1_HUMAN" 2 1770.9087 1.1 50695 17038 3 1770.908009 591.3102 Actin-related protein 2 OS=Homo sapiens OX=9606 GN=ACTR2 PE=1 SV=1 8.75 2955.5 - 696902 - - - -0.3845 - 2.938 0.536 - 384.6 1 2 0 -0.0007 17 0 0 0 2.34E+06 2.12E+06 - - - 7.2384 0.9998 221125_WJC_METTL3_EV_vs_WT_F04.17039.17039.3 0.000301 20/68 R.GVVGGVTGIITKPVEGAK.K "sp|Q709C8|VP13C_HUMAN,tr|A0A3B3IU50|A0A3B3IU50_HUMAN" 2 1680.9774 0.65 50696 17039 3 1680.985287 561.3331 Vacuolar protein sorting-associated protein 13C OS=Homo sapiens OX=9606 GN=VPS13C PE=1 SV=1 8.59 2955.6 - 696475 - - - 4.6794 - 3.378 0.5 - 356.1 1 2 0 0.0079 18 0 0 0 2.91E+06 4.52E+06 - - - 7.1435 1 221125_WJC_METTL3_EV_vs_WT_F04.17040.17040.3 2.04E-05 13/36 R.R[166.11]GDLPFVVPR[166.11].R sp|P35579|MYH9_HUMAN 1 1174.6726 1.08 50697 17040 3 1174.671935 392.5648 Myosin-9 OS=Homo sapiens OX=9606 GN=MYH9 PE=1 SV=4 9.6 2955.7 - 578679 - - - -0.538 - 2.606 0.49 - 340.4 1 2 0 -0.0006 10 0 0 0 4.59E+06 4.25E+06 - - - 6.8001 0.9898 221125_WJC_METTL3_EV_vs_WT_F04.17041.17041.3 0.000557 16/48 R.PGPGVWDPNWDR[166.11]R[166.11].E sp|Q96HS1|PGAM5_HUMAN 1 1570.7544 2.66 50698 17041 3 1570.751851 524.5921 "Serine\threonine-protein phosphatase PGAM5, mitochondrial OS=Homo sapiens OX=9606 GN=PGAM5 PE=1 SV=2" 6.39 2955.8 - 543078 - - - -1.6222 - 2.528 0.403 - 277 1 1 0 -0.0025 13 0 0 0 2.20E+07 8.27E+06 - - - 5.5469 1 221125_WJC_METTL3_EV_vs_WT_F04.17043.17043.3 3.05E-10 14/64 R.TYADYESVNEC[160.03]MEGVC[160.03]K[136.11].M "sp|P84090|ERH_HUMAN,tr|G3V279|G3V279_HUMAN" 2 2061.8209 1.95 50700 17043 3 2061.817574 688.2809 Enhancer of rudimentary homolog OS=Homo sapiens OX=9606 GN=ERH PE=1 SV=1 4 2956.1 - 494655 - - - -1.6272 - 2.759 0.773 - 196.8 1 2 0 -0.0034 17 0 0 0 2.77E+07 1.42E+07 - - - 9.7211 0.9981 221125_WJC_METTL3_EV_vs_WT_F04.17044.17044.2 0.00154 26-Nov K.TLAEHQQLIPLVEK[136.11].A "sp|Q9Y5K5|UCHL5_HUMAN,tr|H0Y4K0|H0Y4K0_HUMAN,tr|H0Y4E0|H0Y4E0_HUMAN,tr|Q5LJA9|Q5LJA9_HUMAN,tr|H0Y636|H0Y636_HUMAN,tr|H0Y6Y4|H0Y6Y4_HUMAN,tr|Q5LJA5|Q5LJA5_HUMAN" 7 1625.9232 1.58 50701 17044 2 1625.917311 813.9689 Ubiquitin carboxyl-terminal hydrolase isozyme L5 OS=Homo sapiens OX=9606 GN=UCHL5 PE=1 SV=3 5.37 2956.2 - 419368 - - - -3.6262 - 2.021 0.397 - 265.6 1 2 0 -0.0059 14 0 0 0 3.98E+06 2.52E+06 - - - 3.737 0.9936 221125_WJC_METTL3_EV_vs_WT_F04.17045.17045.3 5.43E-06 19/60 R.PVQFPYVTPAPHEPVK.T "sp|O60291|MGRN1_HUMAN,tr|K7EJN3|K7EJN3_HUMAN,tr|B4DR12|B4DR12_HUMAN,tr|K7EIM7|K7EIM7_HUMAN,tr|K7ERA1|K7ERA1_HUMAN,tr|K7EPJ5|K7EPJ5_HUMAN" 6 1804.9512 1.09 50702 17045 3 1804.955422 602.6577 E3 ubiquitin-protein ligase MGRN1 OS=Homo sapiens OX=9606 GN=MGRN1 PE=1 SV=2 7.17 2956.3 - 406009 - - - 2.3358 - 3.087 0.475 - 331.6 1 1 0 0.0042 16 0 0 0 2.36E+06 2.17E+06 - - - 6.7269 0.9979 221125_WJC_METTL3_EV_vs_WT_F04.17046.17046.3 1.28 Nov-40 R.DLK[136.11]PQNLLINR[166.11].N sp|Q00535|CDK5_HUMAN 1 1340.7895 0.3 50703 17046 3 1340.789374 447.9371 Cyclin-dependent-like kinase 5 OS=Homo sapiens OX=9606 GN=CDK5 PE=1 SV=3 8.75 2956.5 - 399760 - - - -0.097 - 1.834 0.227 - 144.5 1 2 0 -0.0001 11 0 0 0 8.17E+06 2.69E+07 - - - 2.7938 1 221125_WJC_METTL3_EV_vs_WT_F04.17051.17051.3 2.02E-06 Dec-52 K.TLAEHQQLIPLVEK.A "sp|Q9Y5K5|UCHL5_HUMAN,tr|H0Y4K0|H0Y4K0_HUMAN,tr|H0Y4E0|H0Y4E0_HUMAN,tr|Q5LJA9|Q5LJA9_HUMAN,tr|H0Y636|H0Y636_HUMAN,tr|H0Y6Y4|H0Y6Y4_HUMAN,tr|Q5LJA5|Q5LJA5_HUMAN" 7 1617.909 1.72 50707 17051 3 1617.90933 540.3103 Ubiquitin carboxyl-terminal hydrolase isozyme L5 OS=Homo sapiens OX=9606 GN=UCHL5 PE=1 SV=3 5.37 2957.1 - 7.68E+06 - - - 0.1996 - 2.262 0.525 - 97.3 1 2 0 0.0003 14 0 0 0 8.07E+07 4.70E+07 - - - 6.5623 1 221125_WJC_METTL3_EV_vs_WT_F04.17053.17053.3 0.000613 19/52 K.NELLPSHPLELSEK.N sp|Q9Y244|POMP_HUMAN 1 1604.841 2.08 50709 17053 3 1604.842673 535.9543 Proteasome maturation protein OS=Homo sapiens OX=9606 GN=POMP PE=1 SV=1 4.75 2957.2 - 6.44E+06 - - - 1.0506 - 2.926 0.495 - 624.9 1 2 0 0.0017 14 0 0 0 1.41E+08 6.80E+07 - - - 6.9115 1 221125_WJC_METTL3_EV_vs_WT_F04.17054.17054.2 2.67E-13 20/32 R.TYADYESVNEC[160.03]MEGVC[160.03]K.M "sp|P84090|ERH_HUMAN,tr|G3V279|G3V279_HUMAN" 2 2053.8067 2.2 50710 17054 2 2053.806493 1027.9106 Enhancer of rudimentary homolog OS=Homo sapiens OX=9606 GN=ERH PE=1 SV=1 4 2957.3 - 2.95E+06 - - - -0.1149 - 3.83 0.775 - 967.7 1 2 0 -0.0002 17 0 0 0 3.93E+07 1.79E+07 - - - 8.0666 0.9908 221125_WJC_METTL3_EV_vs_WT_F04.17055.17055.2 5.59E-05 28-Oct R.GLGVGFGSGGGSSSS.V sp|P13647|K2C5_HUMAN 1 1211.5418 - 50711 17055 2 1211.541884 606.7782 "Keratin, type II cytoskeletal 5 OS=Homo sapiens OX=9606 GN=KRT5 PE=1 SV=3" 5.52 2957.4 - 2.18E+06 - - - 0.0322 - 1.859 0.527 - 263.1 1 1 0 0 15 0 0 0 - - - - - 4.4578 0.9766 221125_WJC_METTL3_EV_vs_WT_F04.17056.17056.3 0.000859 Dec-48 R.PGPGVWDPNWDRR.E sp|Q96HS1|PGAM5_HUMAN 1 1550.7379 1.34 50712 17056 3 1550.735869 517.9199 "Serine\threonine-protein phosphatase PGAM5, mitochondrial OS=Homo sapiens OX=9606 GN=PGAM5 PE=1 SV=2" 6.39 2957.4 - 1.23E+06 - - - -1.2833 - 1.915 0.383 - 127.5 1 1 0 -0.002 13 0 0 0 1.01E+07 7.51E+06 - - - 4.5711 0.9994 221125_WJC_METTL3_EV_vs_WT_F04.17057.17057.3 0.00766 Sep-48 K.ILELLRPDPNTGK.V "sp|Q15393|SF3B3_HUMAN,tr|I3L4G7|I3L4G7_HUMAN" 2 1464.83 1.51 50713 17057 3 1464.83161 489.284 Splicing factor 3B subunit 3 OS=Homo sapiens OX=9606 GN=SF3B3 PE=1 SV=4 6.07 2957.5 - 999144 - - - 1.0793 - 1.791 0.334 - 120 1 2 0 0.0016 13 0 0 0 1.10E+07 7.26E+06 - - - 3.8434 0.9965 221125_WJC_METTL3_EV_vs_WT_F04.17059.17059.3 0.0142 Aug-36 K.WDK[136.11]DNLQILR[166.11].D "sp|Q9BXJ9|NAA15_HUMAN,tr|A0A0B4J1W3|A0A0B4J1W3_HUMAN" 2 1317.716 1.16 50715 17059 3 1317.715762 440.2459 "N-alpha-acetyltransferase 15, NatA auxiliary subunit OS=Homo sapiens OX=9606 GN=NAA15 PE=1 SV=1" 5.96 2957.7 - 847988 - - - -0.1844 - 1.866 0.282 - 128.2 1 2 1 -0.0002 10 0 0 0 6.57E+06 5.66E+06 - - - 3.5057 1 221125_WJC_METTL3_EV_vs_WT_F04.17060.17060.3 2.07E-06 13/44 R.TGQPMIHIYLDK.E "sp|Q01844|EWS_HUMAN,tr|B0QYK0|B0QYK0_HUMAN,tr|H7BY36|H7BY36_HUMAN,tr|A0A0D9SFL3|A0A0D9SFL3_HUMAN,tr|C9JGE3|C9JGE3_HUMAN" 5 1414.7279 0.65 50716 17060 3 1414.728328 472.5832 RNA-binding protein EWS OS=Homo sapiens OX=9606 GN=EWSR1 PE=1 SV=1 6.41 2957.8 - 738818 - - - 0.3223 - 3.01 0.436 - 335.3 1 2 0 0.0005 12 0 0 0 1.78E+08 2.72E+08 - - - 6.4553 0.9999 221125_WJC_METTL3_EV_vs_WT_F04.17061.17061.2 5.09E-05 14/26 R.ESESAPGDFSLSVK.F "sp|P62993|GRB2_HUMAN,tr|J3KT38|J3KT38_HUMAN" 2 1451.678 0.83 50717 17061 2 1451.678785 726.8463 Growth factor receptor-bound protein 2 OS=Homo sapiens OX=9606 GN=GRB2 PE=1 SV=1 4.14 2957.9 - 607999 - - - 0.538 - 2.275 0.543 - 479.3 1 2 0 0.0008 14 0 0 0 1.13E+07 1.37E+07 - - - 5.1141 1 221125_WJC_METTL3_EV_vs_WT_F04.17062.17062.2 7.16E-10 15/26 K.DYGVYLEDSGHTLR[166.11].G "sp|Q13162|PRDX4_HUMAN,tr|H7C3T4|H7C3T4_HUMAN" 2 1633.7612 0.39 50718 17062 2 1633.760409 817.8879 Peroxiredoxin-4 OS=Homo sapiens OX=9606 GN=PRDX4 PE=1 SV=1 4.54 2958.1 - 455896 - - - -0.4658 - 2.766 0.67 - 711.6 1 2 0 -0.0008 14 0 0 0 2.17E+06 5.60E+06 - - - 6.5425 0.9998 221125_WJC_METTL3_EV_vs_WT_F04.17063.17063.2 0.0175 28-Dec K.IQNTGDYYDLYGGEK[136.11].F "sp|Q06124|PTN11_HUMAN,tr|A0A1W2PPU4|A0A1W2PPU4_HUMAN" 2 1742.7879 0.54 50719 17063 2 1742.784669 872.4012 Tyrosine-protein phosphatase non-receptor type 11 OS=Homo sapiens OX=9606 GN=PTPN11 PE=1 SV=3 4.03 2958.2 - 398174 - - - -1.8511 - 2.663 0.53 - 511.3 1 2 0 -0.0032 15 0 0 0 1.22E+06 2.28E+06 - - - 5.3626 0.9932 221125_WJC_METTL3_EV_vs_WT_F04.17064.17064.3 0.101 13/76 R.LYLASHPQYAGPGAEAAFSR[166.11].R sp|Q9NRF2|SH2B1_HUMAN 1 2115.0413 0.63 50720 17064 3 2115.03388 706.021 SH2B adapter protein 1 OS=Homo sapiens OX=9606 GN=SH2B1 PE=1 SV=3 6.75 2958.3 - 315691 - - - -3.5125 - 2.072 0.255 - 104.5 1 2 0 -0.0074 20 0 0 0 5.49E+05 8.70E+05 - - - 3.1483 1 221125_WJC_METTL3_EV_vs_WT_F04.17065.17065.2 1.66E-06 13/26 K.SSGEIVYC[160.03]GQVFEK[136.11].S "sp|Q02543|RL18A_HUMAN,tr|M0R3D6|M0R3D6_HUMAN,tr|M0R0P7|M0R0P7_HUMAN,tr|M0R117|M0R117_HUMAN,tr|M0R1A7|M0R1A7_HUMAN" 5 1609.7538 0.93 50721 17065 2 1609.744111 805.8842 60S ribosomal protein L18a OS=Homo sapiens OX=9606 GN=RPL18A PE=1 SV=2 4.53 2958.4 - 2.71E+06 - - - -5.9935 - 2.415 0.62 - 536.8 1 2 0 -0.0096 14 0 0 0 2.13E+07 2.28E+07 - - - 5.8299 0.9996 221125_WJC_METTL3_EV_vs_WT_F04.17066.17066.3 0.0152 Aug-40 R.GFAFVEYESHR[166.11].A "sp|A0AV96|RBM47_HUMAN,sp|Q9NQ94|A1CF_HUMAN,sp|Q8TBY0|RBM46_HUMAN,tr|Q5T0W7|Q5T0W7_HUMAN,tr|D6RBS9|D6RBS9_HUMAN,tr|B7Z8Z7|B7Z8Z7_HUMAN,tr|F8W9F8|F8W9F8_HUMAN,tr|D6R9D6|D6R9D6_HUMAN" 8 1350.6232 1.16 50722 17066 3 1350.622391 451.215 RNA-binding protein 47 OS=Homo sapiens OX=9606 GN=RBM47 PE=1 SV=2 5.4 2958.6 - 204391 - - - -0.6138 - 1.759 0.343 - 70.5 1 2 0 -0.0008 11 0 0 0 1.85E+06 1.59E+06 - - - 3.9682 1 221125_WJC_METTL3_EV_vs_WT_F04.17068.17068.3 8.80E-07 Nov-48 R.HPDVEVDGFSELR[166.11].W "sp|P09874|PARP1_HUMAN,tr|A0A7I2V384|A0A7I2V384_HUMAN,tr|A0A7I2V5E9|A0A7I2V5E9_HUMAN,tr|A0A7I2V625|A0A7I2V625_HUMAN,tr|A0A7I2V3E1|A0A7I2V3E1_HUMAN" 5 1508.7135 0.61 50723 17068 3 1508.712856 503.9118 Poly [ADP-ribose] polymerase 1 OS=Homo sapiens OX=9606 GN=PARP1 PE=1 SV=4 4.31 2958.8 - 407127 - - - -0.4216 - 2.481 0.52 - 133.9 1 2 0 -0.0006 13 0 0 0 6.42E+06 1.05E+07 - - - 6.801 1 221125_WJC_METTL3_EV_vs_WT_F04.17070.17070.3 6.82E-09 18/52 K.DYGVYLEDSGHTLR.G "sp|Q13162|PRDX4_HUMAN,tr|H7C3T4|H7C3T4_HUMAN" 2 1623.7529 0.76 50724 17070 3 1623.753637 542.2582 Peroxiredoxin-4 OS=Homo sapiens OX=9606 GN=PRDX4 PE=1 SV=1 4.54 2959 - 5.70E+06 - - - 0.4539 - 2.983 0.491 - 385.4 1 2 0 0.0007 14 0 0 0 3.49E+07 4.61E+07 - - - 6.9185 1 221125_WJC_METTL3_EV_vs_WT_F04.17071.17071.2 3.78E-13 14/24 K.FC[160.03]ADSDGFSQELR.N "sp|P52732|KIF11_HUMAN,tr|A0A7I2V3A9|A0A7I2V3A9_HUMAN" 2 1530.6409 4.36 50725 17071 2 1530.64079 766.3277 Kinesin-like protein KIF11 OS=Homo sapiens OX=9606 GN=KIF11 PE=1 SV=2 4.03 2959 - 4.62E+06 - - - -0.0764 - 2.984 0.613 - 714.9 1 2 0 -0.0001 13 0 0 0 3.73E+07 8.56E+06 - - - 6.3745 1 221125_WJC_METTL3_EV_vs_WT_F04.17073.17073.2 2.46E-12 19/32 R.TYADYESVNEC[160.03]MEGVC[160.03]K[136.11].M "sp|P84090|ERH_HUMAN,tr|G3V279|G3V279_HUMAN" 2 2061.8209 2.2 50727 17073 2 2061.820296 1031.9177 Enhancer of rudimentary homolog OS=Homo sapiens OX=9606 GN=ERH PE=1 SV=1 4 2959.2 - 2.29E+06 - - - -0.307 - 3.655 0.815 - 847.2 1 2 0 -0.0006 17 0 0 0 3.93E+07 1.79E+07 - - - 8.2469 1 221125_WJC_METTL3_EV_vs_WT_F04.17074.17074.2 1.91E-09 15/28 K.QDLPNAMNAAEITDK.L "sp|P84077|ARF1_HUMAN,sp|P61204|ARF3_HUMAN,tr|H0YGG7|H0YGG7_HUMAN" 3 1629.7668 1.33 50728 17074 2 1629.767385 815.8907 ADP-ribosylation factor 1 OS=Homo sapiens OX=9606 GN=ARF1 PE=1 SV=2 4.03 2959.3 - 1.48E+06 - - - 0.3369 - 3.128 0.649 - 745 1 2 0 0.0005 15 0 0 0 1.52E+08 1.14E+08 - - - 6.6381 0.9997 221125_WJC_METTL3_EV_vs_WT_F04.17076.17076.3 0.000149 15/56 R.IDVLDPEELK[136.11]SESAK[136.11].E "sp|Q9BVG4|PBDC1_HUMAN,tr|A6NDF3|A6NDF3_HUMAN" 2 1687.8851 1.03 50730 17076 3 1687.888261 563.6356 Protein PBDC1 OS=Homo sapiens OX=9606 GN=PBDC1 PE=1 SV=1 4.18 2959.5 - 570832 - - - 1.8745 - 3.022 0.438 - 250.1 1 2 1 0.0032 15 0 0 0 1.39E+07 1.35E+07 - - - 6.3081 0.9998 221125_WJC_METTL3_EV_vs_WT_F04.17077.17077.2 5.93E-06 22-Dec R.TGQPMIHIYLDK[136.11].E "sp|Q01844|EWS_HUMAN,tr|B0QYK0|B0QYK0_HUMAN,tr|H7BY36|H7BY36_HUMAN,tr|A0A0D9SFL3|A0A0D9SFL3_HUMAN,tr|C9JGE3|C9JGE3_HUMAN" 5 1422.7421 1.16 50731 17077 2 1422.742244 712.3783 RNA-binding protein EWS OS=Homo sapiens OX=9606 GN=EWSR1 PE=1 SV=1 6.41 2959.6 - 509814 - - - 0.1209 - 2.376 0.418 - 203.8 1 2 0 0.0002 12 0 0 0 3.15E+07 2.73E+07 - - - 4.4054 0.9999 221125_WJC_METTL3_EV_vs_WT_F04.17078.17078.2 3.92E-05 18-Dec R.QSC[160.03]YLC[160.03]DLPR.M "sp|Q7Z5L9|I2BP2_HUMAN,sp|Q9H1B7|I2BPL_HUMAN" 2 1310.5747 1.53 50732 17078 2 1310.572651 656.2946 Interferon regulatory factor 2-binding protein 2 OS=Homo sapiens OX=9606 GN=IRF2BP2 PE=1 SV=2 5.82 2959.7 - 494539 - - - -1.5955 - 2.326 0.581 - 919.4 1 2 0 -0.0021 10 0 0 0 1.08E+07 7.08E+06 - - - 5.6879 0.9999 221125_WJC_METTL3_EV_vs_WT_F04.17079.17079.3 5.76E-05 Dec-40 K.HFSVEGQLEFR.A "sp|P08238|HS90B_HUMAN,sp|Q58FF7|H90B3_HUMAN,sp|Q58FG1|HS904_HUMAN,sp|P07900|HS90A_HUMAN,sp|Q14568|HS902_HUMAN" 5 1347.6571 0.7 50733 17079 3 1347.656859 450.2263 Heat shock protein HSP 90-beta OS=Homo sapiens OX=9606 GN=HSP90AB1 PE=1 SV=4 5.4 2959.9 - 475539 - - - -0.2152 - 2.39 0.409 - 330.5 1 2 0 -0.0003 11 0 0 0 6.79E+07 9.69E+07 - - - 5.5751 0.9999 221125_WJC_METTL3_EV_vs_WT_F04.17081.17081.3 6.01E-07 18/80 R.ATTPADGEEPAPEAEALAAAR.E "sp|Q96S44|PRPK_HUMAN,tr|Q5JZ02|Q5JZ02_HUMAN" 2 2036.9651 1.13 50735 17081 3 2036.958493 679.9956 EKC\KEOPS complex subunit TP53RK OS=Homo sapiens OX=9606 GN=TP53RK PE=1 SV=2 3.91 2960.1 - 375270 - - - -3.2328 - 2.942 0.567 - 294.8 1 2 0 -0.0066 21 0 0 0 3.10E+06 2.75E+06 - - - 7.4467 1 221125_WJC_METTL3_EV_vs_WT_F04.17083.17083.2 2.03E-08 13/36 R.LGLGGNAPVSIPQQSQSVK[136.11].Q "sp|Q9H2P0|ADNP_HUMAN,tr|A0A2R8Y6X0|A0A2R8Y6X0_HUMAN,tr|A0A669KBJ7|A0A669KBJ7_HUMAN" 3 1887.0305 1.22 50737 17083 2 1887.031068 944.5225 Activity-dependent neuroprotector homeobox protein OS=Homo sapiens OX=9606 GN=ADNP PE=1 SV=1 8.75 2960.4 - 323757 - - - 0.2872 - 3.031 0.546 - 256.1 1 2 0 0.0005 19 0 0 0 9.56E+06 7.84E+06 - - - 5.7998 1 221125_WJC_METTL3_EV_vs_WT_F04.17089.17089.2 3.11E-08 13/26 R.SGGIETIANEYSDR.C "sp|O95757|HS74L_HUMAN,tr|D6RJ96|D6RJ96_HUMAN" 2 1510.69 0.09 50742 17089 2 1510.691436 756.3523 Heat shock 70 kDa protein 4L OS=Homo sapiens OX=9606 GN=HSPA4L PE=1 SV=3 4.14 2961.1 - 530426 - - - 0.9731 - 2.851 0.653 - 569.6 1 2 0 0.0015 14 0 0 0 4.63E+06 5.04E+07 - - - 6.4927 0.9999 221125_WJC_METTL3_EV_vs_WT_F04.17091.17091.3 0.0146 Sep-44 K.EYR[166.11]PETGSWVFK[136.11].V "sp|P52948|NUP98_HUMAN,tr|A0A3B3ITD8|A0A3B3ITD8_HUMAN" 2 1515.7477 1.73 50743 17091 3 1515.748634 506.2565 Nuclear pore complex protein Nup98-Nup96 OS=Homo sapiens OX=9606 GN=NUP98 PE=1 SV=4 6.24 2961.4 - 9.40E+06 - - - 0.6169 - 1.63 0.442 - 113.5 1 2 0 0.0009 12 0 0 0 1.66E+08 9.61E+07 - - - 4.8219 1 221125_WJC_METTL3_EV_vs_WT_F04.17093.17093.2 1.66E-06 15/26 K.DISTTLNADEAVAR[166.11].G "sp|Q92598|HS105_HUMAN,sp|O95757|HS74L_HUMAN,tr|D6RJ96|D6RJ96_HUMAN,tr|E9PDE8|E9PDE8_HUMAN,tr|A0A0A0MSM0|A0A0A0MSM0_HUMAN" 5 1484.7346 0.16 50745 17093 2 1484.733709 743.3746 Heat shock protein 105 kDa OS=Homo sapiens OX=9606 GN=HSPH1 PE=1 SV=1 4.03 2961.5 - 3.21E+06 - - - -0.6143 - 2.964 0.578 - 678.7 1 2 0 -0.0009 14 0 0 0 4.62E+06 2.92E+07 - - - 6.0364 0.9998 221125_WJC_METTL3_EV_vs_WT_F04.17096.17096.2 0.00307 20-Dec K.AVSDWIDEQEK.G "sp|Q12906|ILF3_HUMAN,tr|K7EM82|K7EM82_HUMAN,tr|K7ER69|K7ER69_HUMAN,tr|K7EQ75|K7EQ75_HUMAN,tr|K7ENK6|K7ENK6_HUMAN,tr|K7EJ09|K7EJ09_HUMAN,tr|K7ERM6|K7ERM6_HUMAN,tr|K7EKJ9|K7EKJ9_HUMAN" 8 1318.6041 1.12 50748 17096 2 1318.601992 660.3093 Interleukin enhancer-binding factor 3 OS=Homo sapiens OX=9606 GN=ILF3 PE=1 SV=3 3.92 2961.7 - 1.64E+06 - - - -1.607 - 2.453 0.491 - 442.2 1 2 0 -0.0021 11 0 0 0 1.57E+07 1.41E+07 - - - 5.0943 1 221125_WJC_METTL3_EV_vs_WT_F04.17098.17098.2 7.50E-05 14/28 R.VTFEADENENITVVK.G "sp|Q9NX63|MIC19_HUMAN,tr|F8WAR4|F8WAR4_HUMAN,tr|C9JRZ6|C9JRZ6_HUMAN" 3 1706.8363 2.34 50750 17098 2 1706.835174 854.4254 MICOS complex subunit MIC19 OS=Homo sapiens OX=9606 GN=CHCHD3 PE=1 SV=1 4 2961.9 - 903718 - - - -0.6574 - 2.689 0.578 - 499.1 1 2 0 -0.0011 15 0 0 0 1.67E+07 7.13E+06 - - - 5.7417 1 221125_WJC_METTL3_EV_vs_WT_F04.17102.17102.2 2.59E-08 15/36 R.LGLGGNAPVSIPQQSQSVK.Q "sp|Q9H2P0|ADNP_HUMAN,tr|A0A2R8Y6X0|A0A2R8Y6X0_HUMAN,tr|A0A669KBJ7|A0A669KBJ7_HUMAN" 3 1879.0163 1.22 50754 17102 2 1879.016802 940.5154 Activity-dependent neuroprotector homeobox protein OS=Homo sapiens OX=9606 GN=ADNP PE=1 SV=1 8.75 2962.4 - 644572 - - - 0.2533 - 3 0.563 - 316.9 1 2 0 0.0005 19 0 0 0 9.56E+06 7.84E+06 - - - 5.9002 0.9998 221125_WJC_METTL3_EV_vs_WT_F04.17103.17103.2 2.62E-05 14/26 K.NSPLLSVSSQTITK.E "sp|Q8ND24|RN214_HUMAN,tr|E9PRE9|E9PRE9_HUMAN" 2 1473.8039 3.31 50755 17103 2 1473.807133 737.9092 RING finger protein 214 OS=Homo sapiens OX=9606 GN=RNF214 PE=1 SV=2 8.75 2962.6 - 592179 - - - 2.212 - 2.759 0.525 - 588.6 1 2 0 0.0033 14 0 0 0 7.49E+06 2.26E+06 - - - 5.4644 0.9998 221125_WJC_METTL3_EV_vs_WT_F04.17105.17105.2 1.29E-05 26-Aug K.DYGVYLEDSGHTLR.G "sp|Q13162|PRDX4_HUMAN,tr|H7C3T4|H7C3T4_HUMAN" 2 1623.7529 0.39 50757 17105 2 1623.754515 812.8837 Peroxiredoxin-4 OS=Homo sapiens OX=9606 GN=PRDX4 PE=1 SV=1 4.54 2962.8 - 311336 - - - 0.9946 - 1.981 0.536 - 211.1 1 2 0 0.0016 14 0 0 0 2.17E+06 5.60E+06 - - - 4.7149 0.9998 221125_WJC_METTL3_EV_vs_WT_F04.17109.17109.2 0.000124 13/26 R.ESESAPGDFSLSVK[136.11].F "sp|P62993|GRB2_HUMAN,tr|J3KT38|J3KT38_HUMAN" 2 1459.6922 0.83 50760 17109 2 1459.693395 730.8534 Growth factor receptor-bound protein 2 OS=Homo sapiens OX=9606 GN=GRB2 PE=1 SV=1 4.14 2963.3 - 1.05E+06 - - - 0.8159 - 1.917 0.52 - 367 1 2 0 0.0012 14 0 0 0 1.13E+07 1.37E+07 - - - 4.5144 0.9997 221125_WJC_METTL3_EV_vs_WT_F04.17110.17110.2 2.68E-05 13/22 K.EYRPETGSWVFK.V "sp|P52948|NUP98_HUMAN,tr|A0A3B3ITD8|A0A3B3ITD8_HUMAN" 2 1497.7252 2.21 50761 17110 2 1497.727866 749.8699 Nuclear pore complex protein Nup98-Nup96 OS=Homo sapiens OX=9606 GN=NUP98 PE=1 SV=4 6.24 2963.4 - 1.44E+06 - - - 1.7607 - 2.389 0.402 - 561.3 1 2 0 0.0026 12 0 0 0 1.65E+07 7.45E+06 - - - 4.3008 0.9987 221125_WJC_METTL3_EV_vs_WT_F04.17111.17111.3 0.0175 Jul-44 R.EDAMAMVDHC[160.03]LK[136.11].K "sp|P43243|MATR3_HUMAN,tr|B3KM87|B3KM87_HUMAN,tr|A8MXP9|A8MXP9_HUMAN,tr|A0A0R4J2E8|A0A0R4J2E8_HUMAN,tr|H0Y8T4|H0Y8T4_HUMAN,tr|D6REM6|D6REM6_HUMAN" 6 1426.6134 1.39 50762 17111 3 1426.608149 476.5451 Matrin-3 OS=Homo sapiens OX=9606 GN=MATR3 PE=1 SV=2 4.54 2963.5 - 1.79E+07 - - - -3.7102 - 1.747 0.402 - 59.5 1 2 0 -0.0053 12 0 0 0 5.76E+07 4.16E+07 - - - 4.5669 0.9999 221125_WJC_METTL3_EV_vs_WT_F04.17112.17112.3 0.000763 Oct-40 K.AETDHLFDLSR[166.11].R "sp|Q9NPF5|DMAP1_HUMAN,tr|Q5TG39|Q5TG39_HUMAN,tr|Q5TG38|Q5TG38_HUMAN,tr|Q5TG40|Q5TG40_HUMAN,tr|Q5TG37|Q5TG37_HUMAN" 5 1312.6287 1.15 50763 17112 3 1312.627499 438.5502 DNA methyltransferase 1-associated protein 1 OS=Homo sapiens OX=9606 GN=DMAP1 PE=1 SV=1 4.54 2963.5 - 1.73E+06 - - - -0.915 - 1.971 0.396 - 217.2 1 2 0 -0.0012 11 0 0 0 4.54E+07 3.95E+07 - - - 4.8823 1 221125_WJC_METTL3_EV_vs_WT_F04.17113.17113.2 7.04E-06 15/20 K.HFSVEGQLEFR[166.11].A "sp|P08238|HS90B_HUMAN,sp|Q58FF7|H90B3_HUMAN,sp|Q58FG1|HS904_HUMAN,sp|P07900|HS90A_HUMAN,sp|Q14568|HS902_HUMAN" 5 1357.6654 0.74 50764 17113 2 1357.66529 679.84 Heat shock protein HSP 90-beta OS=Homo sapiens OX=9606 GN=HSP90AB1 PE=1 SV=4 5.4 2963.6 - 1.71E+06 - - - -0.095 - 2.862 0.627 - 624.1 1 2 0 -0.0001 11 0 0 0 2.52E+07 3.42E+07 - - - 6.5166 1 221125_WJC_METTL3_EV_vs_WT_F04.17114.17114.3 8.34E-06 Nov-40 K.AETDHLFDLSR.R "sp|Q9NPF5|DMAP1_HUMAN,tr|Q5TG39|Q5TG39_HUMAN,tr|Q5TG38|Q5TG38_HUMAN,tr|Q5TG40|Q5TG40_HUMAN,tr|Q5TG37|Q5TG37_HUMAN" 5 1302.6204 1.15 50765 17114 3 1302.619982 435.2141 DNA methyltransferase 1-associated protein 1 OS=Homo sapiens OX=9606 GN=DMAP1 PE=1 SV=1 4.54 2963.7 - 1.43E+06 - - - -0.3439 - 2.291 0.451 - 245.3 1 2 0 -0.0004 11 0 0 0 4.54E+07 3.95E+07 - - - 5.9231 0.9999 221125_WJC_METTL3_EV_vs_WT_F04.17116.17116.3 0.000198 Nov-40 R.KLDVYFEYEEK.L "sp|Q8WVM8|SCFD1_HUMAN,tr|A0A7I2V4U2|A0A7I2V4U2_HUMAN,tr|A0A7I2V4B8|A0A7I2V4B8_HUMAN,tr|H0YIZ7|H0YIZ7_HUMAN,tr|A0A7I2V5Z4|A0A7I2V5Z4_HUMAN,tr|B7Z5N7|B7Z5N7_HUMAN,tr|A0A7I2V5I2|A0A7I2V5I2_HUMAN,tr|A0A7I2V590|A0A7I2V590_HUMAN,tr|G3V5E2|G3V5E2_HUMAN,tr|A0A7I2V2U5|A0A7I2V2U5_HUMAN,tr|A0A7I2V362|A0A7I2V362_HUMAN,tr|A0A7I2V448|A0A7I2V448_HUMAN,tr|A0A7I2V320|A0A7I2V320_HUMAN,tr|A0A7I2V3G4|A0A7I2V3G4_HUMAN,tr|A0A7I2V3B4|A0A7I2V3B4_HUMAN,tr|G3V2M8|G3V2M8_HUMAN,tr|A0A7I2V5H5|A0A7I2V5H5_HUMAN,tr|A0A7I2V4R0|A0A7I2V4R0_HUMAN,tr|A0A7I2YQQ1|A0A7I2YQQ1_HUMAN" 19 1461.7028 1.87 50767 17116 3 1461.703468 488.2415 Sec1 family domain-containing protein 1 OS=Homo sapiens OX=9606 GN=SCFD1 PE=1 SV=4 4.41 2963.9 - 1.39E+06 - - - 0.483 - 2.105 0.434 - 137.4 1 2 0 0.0007 11 0 0 0 1.08E+07 5.75E+06 - - - 5.4929 1 221125_WJC_METTL3_EV_vs_WT_F04.17117.17117.2 2.91E-06 16/24 R.SPDFTNENPLETR[166.11].N sp|P05023|AT1A1_HUMAN 1 1528.7033 3.02 50768 17117 2 1528.697687 765.3589 Sodium\potassium-transporting ATPase subunit alpha-1 OS=Homo sapiens OX=9606 GN=ATP1A1 PE=1 SV=1 4.14 2964 - 1.01E+06 - - - -3.6855 - 3.181 0.674 - 1204.1 1 2 0 -0.0056 13 0 0 0 7.12E+07 2.36E+07 - - - 6.9874 1 221125_WJC_METTL3_EV_vs_WT_F04.17118.17118.3 5.72E-07 18/68 K.AFGSGIDIKPGTPPIAGR.S "sp|Q9Y520|PRC2C_HUMAN,tr|E7EPN9|E7EPN9_HUMAN,tr|A0A2R8Y424|A0A2R8Y424_HUMAN,tr|H7C5N8|H7C5N8_HUMAN,tr|A0A2R8Y7F4|A0A2R8Y7F4_HUMAN,tr|A0A2R8YET2|A0A2R8YET2_HUMAN" 6 1752.9523 12.89 50769 17118 3 1752.953935 585.3247 Protein PRRC2C OS=Homo sapiens OX=9606 GN=PRRC2C PE=1 SV=4 8.79 2964.1 - 893529 - - - 0.9504 - 3.212 0.444 - 275.7 1 2 0 0.0017 18 0 0 0 3.12E+07 2.42E+06 - - - 6.3954 0.9995 221125_WJC_METTL3_EV_vs_WT_F04.17119.17119.3 0.000267 Nov-40 R.K[136.11]LDVYFEYEEK[136.11].L "sp|Q8WVM8|SCFD1_HUMAN,tr|A0A7I2V4U2|A0A7I2V4U2_HUMAN,tr|A0A7I2V4B8|A0A7I2V4B8_HUMAN,tr|H0YIZ7|H0YIZ7_HUMAN,tr|A0A7I2V5Z4|A0A7I2V5Z4_HUMAN,tr|B7Z5N7|B7Z5N7_HUMAN,tr|A0A7I2V5I2|A0A7I2V5I2_HUMAN,tr|A0A7I2V590|A0A7I2V590_HUMAN,tr|G3V5E2|G3V5E2_HUMAN,tr|A0A7I2V2U5|A0A7I2V2U5_HUMAN,tr|A0A7I2V362|A0A7I2V362_HUMAN,tr|A0A7I2V448|A0A7I2V448_HUMAN,tr|A0A7I2V320|A0A7I2V320_HUMAN,tr|A0A7I2V3G4|A0A7I2V3G4_HUMAN,tr|A0A7I2V3B4|A0A7I2V3B4_HUMAN,tr|G3V2M8|G3V2M8_HUMAN,tr|A0A7I2V5H5|A0A7I2V5H5_HUMAN,tr|A0A7I2V4R0|A0A7I2V4R0_HUMAN,tr|A0A7I2YQQ1|A0A7I2YQQ1_HUMAN" 19 1477.7312 2 50770 17119 3 1477.72713 493.5843 Sec1 family domain-containing protein 1 OS=Homo sapiens OX=9606 GN=SCFD1 PE=1 SV=4 4.41 2964.2 - 866697 - - - -2.7285 - 1.939 0.384 - 135.3 1 2 0 -0.004 11 0 0 0 1.05E+07 5.23E+06 - - - 4.7012 1 221125_WJC_METTL3_EV_vs_WT_F04.17121.17121.3 4.97E-11 22/60 K.FLC[160.03]ADYAEQDELDYHR.G "sp|Q9UKV3|ACINU_HUMAN,tr|G3V3B0|G3V3B0_HUMAN,tr|S4R3H4|S4R3H4_HUMAN,tr|E7EQT4|E7EQT4_HUMAN" 4 2043.8633 1.74 50772 17121 3 2043.860905 682.295 Apoptotic chromatin condensation inducer in the nucleus OS=Homo sapiens OX=9606 GN=ACIN1 PE=1 SV=2 4.1 2964.4 - 716154 - - - -1.1503 - 3.252 0.655 - 524.4 1 2 0 -0.0024 16 0 0 0 2.41E+07 1.39E+07 - - - 8.8678 1 221125_WJC_METTL3_EV_vs_WT_F04.17123.17123.2 8.98E-08 22-Dec R.EDAMAMVDHC[160.03]LK[136.11].K "sp|P43243|MATR3_HUMAN,tr|B3KM87|B3KM87_HUMAN,tr|A8MXP9|A8MXP9_HUMAN,tr|A0A0R4J2E8|A0A0R4J2E8_HUMAN,tr|H0Y8T4|H0Y8T4_HUMAN,tr|D6REM6|D6REM6_HUMAN" 6 1426.6134 1.39 50774 17123 2 1426.61245 714.314 Matrin-3 OS=Homo sapiens OX=9606 GN=MATR3 PE=1 SV=2 4.54 2964.7 - 627099 - - - -0.6954 - 2.467 0.609 - 316.8 1 2 0 -0.001 12 0 0 0 8.28E+06 5.94E+06 - - - 5.9147 1 221125_WJC_METTL3_EV_vs_WT_F04.17126.17126.3 2.80E-07 19/72 K.NLPPSGAVPVTGIPPHVVK.V "sp|Q13283|G3BP1_HUMAN,tr|A0A7I2V5M7|A0A7I2V5M7_HUMAN,tr|A0A7I2YQM1|A0A7I2YQM1_HUMAN,tr|A0A7P0P2U7|A0A7P0P2U7_HUMAN,tr|A0A7I2YQU8|A0A7I2YQU8_HUMAN,tr|A0A7I2V548|A0A7I2V548_HUMAN,tr|A0A7I2V651|A0A7I2V651_HUMAN,tr|A0A7I2V4D8|A0A7I2V4D8_HUMAN,tr|A0A7I2YQN9|A0A7I2YQN9_HUMAN" 9 1878.0727 1.4 50776 17126 3 1878.077911 627.0315 Ras GTPase-activating protein-binding protein 1 OS=Homo sapiens OX=9606 GN=G3BP1 PE=1 SV=1 8.76 2965 - 2.23E+06 - - - 2.7651 - 2.621 0.606 - 337.5 1 2 0 0.0052 19 0 0 0 2.82E+07 2.01E+07 - - - 7.6621 0.9999 221125_WJC_METTL3_EV_vs_WT_F04.17129.17129.3 0.00024 Dec-52 R.AITHLNNNFMFGQK.L "sp|P14866|HNRPL_HUMAN,tr|M0QYT0|M0QYT0_HUMAN,tr|A0A3B3ITJ4|A0A3B3ITJ4_HUMAN,tr|M0QXS5|M0QXS5_HUMAN" 4 1633.8035 0.65 50778 17129 3 1633.805446 545.6084 Heterogeneous nuclear ribonucleoprotein L OS=Homo sapiens OX=9606 GN=HNRNPL PE=1 SV=2 8.8 2965.3 - 5.12E+06 - - - 1.1935 - 2.255 0.485 - 169.8 1 2 0 0.0019 14 0 0 0 1.10E+08 1.70E+08 - - - 6.1077 0.8341 221125_WJC_METTL3_EV_vs_WT_F04.17130.17130.2 0.0627 22-May R.R[166.11]GGDHHQPLLVC[160.03].A tr|M0R1Y2|M0R1Y2_HUMAN 1 1397.6862 0.01 50779 17130 2 1397.685438 699.8504 ER lumen protein-retaining receptor 1 (Fragment) OS=Homo sapiens OX=9606 GN=KDELR1 PE=1 SV=1 6.91 2965.3 - 4.10E+06 - - - -0.5252 - 1.246 0.245 - 50.2 1 1 0 -0.0007 12 0 0 0 6.05E+05 6.60E+07 - - - 1.429 0.9999 221125_WJC_METTL3_EV_vs_WT_F04.17133.17133.2 1.51E-07 15/24 R.SPDFTNENPLETR.N sp|P05023|AT1A1_HUMAN 1 1518.6951 1.88 50782 17133 2 1518.692718 760.3548 Sodium\potassium-transporting ATPase subunit alpha-1 OS=Homo sapiens OX=9606 GN=ATP1A1 PE=1 SV=1 4.14 2965.6 - 2.11E+06 - - - -1.5362 - 3.061 0.507 - 1038.6 1 2 0 -0.0023 13 0 0 0 5.85E+07 3.11E+07 - - - 5.6563 0.9999 221125_WJC_METTL3_EV_vs_WT_F04.17134.17134.2 9.03E-06 15/26 K.SSGEIVYC[160.03]GQVFEK.S "sp|Q02543|RL18A_HUMAN,tr|M0R3D6|M0R3D6_HUMAN,tr|M0R0P7|M0R0P7_HUMAN,tr|M0R117|M0R117_HUMAN,tr|M0R1A7|M0R1A7_HUMAN" 5 1601.7396 0.93 50783 17134 2 1601.737978 801.8771 60S ribosomal protein L18a OS=Homo sapiens OX=9606 GN=RPL18A PE=1 SV=2 4.53 2965.6 - 2.00E+06 - - - -0.9871 - 2.324 0.558 - 660.4 1 2 0 -0.0016 14 0 0 0 2.13E+07 2.28E+07 - - - 5.2781 0.9998 221125_WJC_METTL3_EV_vs_WT_F04.17135.17135.2 0.0476 20-Nov K.AVSDWIDEQEK[136.11].G "sp|Q12906|ILF3_HUMAN,tr|K7EM82|K7EM82_HUMAN,tr|K7ER69|K7ER69_HUMAN,tr|K7EQ75|K7EQ75_HUMAN,tr|K7ENK6|K7ENK6_HUMAN,tr|K7EJ09|K7EJ09_HUMAN,tr|K7ERM6|K7ERM6_HUMAN,tr|K7EKJ9|K7EKJ9_HUMAN" 8 1326.6183 1.12 50784 17135 2 1326.617157 664.3164 Interleukin enhancer-binding factor 3 OS=Homo sapiens OX=9606 GN=ILF3 PE=1 SV=3 3.92 2965.7 - 1.51E+06 - - - -0.8699 - 2.346 0.426 - 338.5 1 2 0 -0.0012 11 0 0 0 1.57E+07 1.41E+07 - - - 4.4939 0.9316 221125_WJC_METTL3_EV_vs_WT_F04.17136.17136.2 5.92 14-Jun R.VIALAHR[166.11]K[136.11].L "sp|Q9H7F0|AT133_HUMAN,tr|A0A2R8YDN7|A0A2R8YDN7_HUMAN,tr|A0A2R8Y635|A0A2R8Y635_HUMAN" 3 924.5988 0.001 50785 17136 2 924.59995 463.3067 Polyamine-transporting ATPase 13A3 OS=Homo sapiens OX=9606 GN=ATP13A3 PE=1 SV=4 11 2965.8 - 778525 - - - 1.2546 - 1.195 0.033 - 80.4 3 2 0 0.0012 8 0 0 0 0.00E+00 1.56E+07 - - - -0.3915 1 221125_WJC_METTL3_EV_vs_WT_F04.17138.17138.2 5.84E-10 16/28 K.NQVALNPQNTVFDAK[136.11].R "sp|P0DMV8|HS71A_HUMAN,sp|P0DMV9|HS71B_HUMAN,tr|A0A0G2JIW1|A0A0G2JIW1_HUMAN" 3 1665.8566 0.16 50787 17138 2 1665.858645 833.9356 Heat shock 70 kDa protein 1A OS=Homo sapiens OX=9606 GN=HSPA1A PE=1 SV=1 5.84 2966.1 - 712929 - - - 1.2372 - 3.096 0.647 - 629.9 1 2 0 0.0021 15 0 0 0 2.21E+09 1.41E+10 - - - 6.5975 0.9999 221125_WJC_METTL3_EV_vs_WT_F04.17147.17147.2 3.27E-06 14/26 R.TIQTPIGSTWNTQR.A "sp|Q5TAP6|UT14C_HUMAN,sp|Q9BVJ6|UT14A_HUMAN" 2 1601.8162 1.9 50794 17147 2 1601.815872 801.9154 U3 small nucleolar RNA-associated protein 14 homolog C OS=Homo sapiens OX=9606 GN=UTP14C PE=1 SV=1 9.41 2967.1 - 1.37E+06 - - - -0.1854 - 2.247 0.524 - 545.6 1 2 0 -0.0003 14 0 0 0 1.68E+07 8.86E+06 - - - 4.9428 0.9995 221125_WJC_METTL3_EV_vs_WT_F04.17148.17148.2 4.44E-08 13/28 K.VNQPASFAVSLNGAK[136.11].G "sp|P21333|FLNA_HUMAN,tr|A0A7P0NMY4|A0A7P0NMY4_HUMAN,tr|Q60FE5|Q60FE5_HUMAN" 3 1509.8031 1.22 50795 17148 2 1509.797995 755.9088 Filamin-A OS=Homo sapiens OX=9606 GN=FLNA PE=1 SV=4 8.72 2967.3 - 1.19E+06 - - - -3.3759 - 2.498 0.564 - 629.2 1 2 0 -0.0051 15 0 0 0 2.10E+07 1.72E+07 - - - 5.4559 1 221125_WJC_METTL3_EV_vs_WT_F04.17149.17149.3 4.14E-06 14/44 K.FAQVVLQDLDKK.E sp|Q0VDF9|HSP7E_HUMAN 1 1402.782 0.52 50796 17149 3 1402.781572 468.6013 Heat shock 70 kDa protein 14 OS=Homo sapiens OX=9606 GN=HSPA14 PE=1 SV=1 5.96 2967.4 - 952762 - - - -0.3165 - 2.917 0.573 - 195.9 1 2 0 -0.0004 12 0 0 0 5.42E+06 1.04E+07 - - - 7.8957 0.9984 221125_WJC_METTL3_EV_vs_WT_F04.17153.17153.3 0.0006 Dec-44 R.ATLENDFVVLKK.D sp|Q8N1N4|K2C78_HUMAN 1 1375.7711 10.78 50800 17153 3 1375.776237 459.5976 "Keratin, type II cytoskeletal 78 OS=Homo sapiens OX=9606 GN=KRT78 PE=1 SV=2" 6.11 2967.9 - 736066 - - - 3.7215 - 2.028 0.351 - 138.4 1 2 0 0.0051 12 0 0 0 8.45E+06 7.84E+05 - - - 4.4117 0.9995 221125_WJC_METTL3_EV_vs_WT_F04.17154.17154.3 0.004 Oct-40 K.QMVIDVLHPGK[136.11].A "sp|P62847|RS24_HUMAN,tr|A0A2R8YD14|A0A2R8YD14_HUMAN,tr|A0A2R8Y849|A0A2R8Y849_HUMAN,tr|E7ETK0|E7ETK0_HUMAN" 4 1243.6838 1.83 50801 17154 3 1243.682202 415.5686 40S ribosomal protein S24 OS=Homo sapiens OX=9606 GN=RPS24 PE=1 SV=1 6.74 2968 - 691127 - - - -1.3074 - 1.878 0.328 - 101.2 1 2 0 -0.0016 11 0 0 0 1.31E+07 7.15E+06 - - - 3.9867 0.9999 221125_WJC_METTL3_EV_vs_WT_F04.17157.17157.3 0.000832 Dec-48 K.AGVQEFVDGLHEK[136.11].L "sp|Q9UK61|TASOR_HUMAN,tr|A0A087X0F1|A0A087X0F1_HUMAN" 2 1435.7187 1.22 50804 17157 3 1435.717493 479.5802 Protein TASOR OS=Homo sapiens OX=9606 GN=TASOR PE=1 SV=3 4.65 2968.4 - 397272 - - - -0.8365 - 2.254 0.398 - 143.9 1 2 0 -0.0012 13 0 0 0 7.59E+06 6.23E+06 - - - 5.1805 1 221125_WJC_METTL3_EV_vs_WT_F04.17161.17161.2 9.79E-12 23/28 K.VIEHIMEDLDTNADK.Q sp|P06702|S10A9_HUMAN 1 1741.8193 999 50806 17161 2 1741.817028 871.9169 Protein S100-A9 OS=Homo sapiens OX=9606 GN=S100A9 PE=1 SV=1 4.1 2968.9 - 3.38E+06 - - - -1.2849 - 4.364 0.694 - 2412.6 1 2 0 -0.0022 15 0 0 0 9.90E+07 0.00E+00 - - - 7.7886 1 221125_WJC_METTL3_EV_vs_WT_F04.17162.17162.3 4.90E-10 18/68 R.VAPEEHPVLLTEAPLNPK[136.11].A "sp|P63261|ACTG_HUMAN,sp|P60709|ACTB_HUMAN,tr|A0A804GS07|A0A804GS07_HUMAN,tr|I3L3I0|I3L3I0_HUMAN,tr|G5E9R0|G5E9R0_HUMAN,tr|E7EVS6|E7EVS6_HUMAN,tr|A0A6Q8PFE4|A0A6Q8PFE4_HUMAN,tr|J3KT65|J3KT65_HUMAN,tr|I3L3R2|I3L3R2_HUMAN,tr|K7EM38|K7EM38_HUMAN,tr|A0A6Q8PH58|A0A6Q8PH58_HUMAN,tr|I3L1U9|I3L1U9_HUMAN,tr|A0A2R8Y793|A0A2R8Y793_HUMAN,tr|I3L4N8|I3L4N8_HUMAN,tr|A0A2R8YGF8|A0A2R8YGF8_HUMAN" 15 1961.0713 1.16 50807 17162 3 1961.066437 654.6977 "Actin, cytoplasmic 2 OS=Homo sapiens OX=9606 GN=ACTG1 PE=1 SV=1" 4.75 2969 - 3.86E+06 - - - -2.494 - 3.199 0.565 - 342.6 1 2 0 -0.0049 18 0 0 0 2.93E+09 2.53E+09 - - - 7.7334 1 221125_WJC_METTL3_EV_vs_WT_F04.17163.17163.3 4.28E-10 22/60 K.FLC[160.03]ADYAEQDELDYHR[166.11].G "sp|Q9UKV3|ACINU_HUMAN,tr|G3V3B0|G3V3B0_HUMAN,tr|S4R3H4|S4R3H4_HUMAN,tr|E7EQT4|E7EQT4_HUMAN" 4 2053.8715 1.74 50808 17163 3 2053.870478 685.6311 Apoptotic chromatin condensation inducer in the nucleus OS=Homo sapiens OX=9606 GN=ACIN1 PE=1 SV=2 4.1 2969.1 - 2.67E+06 - - - -0.5103 - 3.227 0.621 - 631.3 1 2 0 -0.001 16 0 0 0 2.41E+07 1.39E+07 - - - 8.4693 1 221125_WJC_METTL3_EV_vs_WT_F04.17165.17165.3 4.57E-07 24/52 K.QIGNVAALPGIVHR.S sp|Q9Y3I0|RTCB_HUMAN 1 1443.831 1.46 50810 17165 3 1443.828197 482.2843 RNA-splicing ligase RtcB homolog OS=Homo sapiens OX=9606 GN=RTCB PE=1 SV=1 9.76 2969.4 - 2.07E+06 - - - -1.9635 - 3.447 0.501 - 770.2 1 2 0 -0.0028 14 0 0 0 1.51E+08 1.04E+08 - - - 7.4136 1 221125_WJC_METTL3_EV_vs_WT_F04.17166.17166.3 6.31E-07 19/52 K.QIGNVAALPGIVHR[166.11].S sp|Q9Y3I0|RTCB_HUMAN 1 1453.8393 1.46 50811 17166 3 1453.837048 485.6204 RNA-splicing ligase RtcB homolog OS=Homo sapiens OX=9606 GN=RTCB PE=1 SV=1 9.76 2969.4 - 1.97E+06 - - - -1.5504 - 3.103 0.513 - 406.8 1 2 0 -0.0023 14 0 0 0 1.51E+08 1.04E+08 - - - 7.2681 0.9998 221125_WJC_METTL3_EV_vs_WT_F04.17167.17167.3 8.19E-05 17/60 R.TSILAAANPISGHYDR[166.11].S sp|Q14566|MCM6_HUMAN 1 1694.8616 0.77 50812 17167 3 1694.856452 565.9611 DNA replication licensing factor MCM6 OS=Homo sapiens OX=9606 GN=MCM6 PE=1 SV=1 6.41 2969.6 - 1.09E+06 - - - -3.0097 - 2.853 0.425 - 396.7 1 2 0 -0.0051 16 0 0 0 7.27E+06 9.43E+06 - - - 5.9669 0.9993 221125_WJC_METTL3_EV_vs_WT_F04.17168.17168.3 0.0106 17/76 R.SLETENSALQLQVTER[166.11]EEVR[166.11].G "sp|P20700|LMNB1_HUMAN,tr|A0A0D9SFY5|A0A0D9SFY5_HUMAN,tr|E9PBF6|E9PBF6_HUMAN,tr|A0A0D9SFE5|A0A0D9SFE5_HUMAN" 4 2350.1879 1.24 50813 17168 3 2350.184658 784.4033 Lamin-B1 OS=Homo sapiens OX=9606 GN=LMNB1 PE=1 SV=2 4.32 2969.7 - 1.03E+06 - - - -1.3893 - 2.768 0.358 - 180.9 1 2 1 -0.0033 20 0 0 0 3.93E+07 3.16E+07 - - - 5.0004 0.9532 221125_WJC_METTL3_EV_vs_WT_F04.17169.17169.3 0.00573 Oct-36 R.FDVQLK[136.11]DLEK[136.11].W "sp|P62244|RS15A_HUMAN,tr|I3L3P7|I3L3P7_HUMAN,tr|H3BVC7|H3BVC7_HUMAN" 3 1249.6889 1.02 50814 17169 3 1249.685762 417.5702 40S ribosomal protein S15a OS=Homo sapiens OX=9606 GN=RPS15A PE=1 SV=2 4.56 2969.8 - 977172 - - - -2.5142 - 2.013 0.16 - 76.2 1 2 1 -0.0031 10 0 0 0 2.75E+07 2.71E+07 - - - 2.3662 0.9985 221125_WJC_METTL3_EV_vs_WT_F04.17170.17170.2 0.00105 26-Nov R.SVGELPSTVESLQK[136.11].V sp|Q07065|CKAP4_HUMAN 1 1480.7864 0.5 50815 17170 2 1480.784392 741.4005 Cytoskeleton-associated protein 4 OS=Homo sapiens OX=9606 GN=CKAP4 PE=1 SV=2 4.53 2970 - 912853 - - - -1.3824 - 2.265 0.19 - 302.9 2 2 0 -0.002 14 0 0 0 1.17E+08 2.34E+08 - - - 2.3609 1 221125_WJC_METTL3_EV_vs_WT_F04.17171.17171.3 1.11E-08 14/56 K.EAIHDMNFSNEDMIR.E "sp|Q96EI5|TCAL4_HUMAN,sp|Q9H3H9|TCAL2_HUMAN,tr|A2RQR6|A2RQR6_HUMAN" 3 1820.7822 1.59 50816 17171 3 1820.779974 607.9347 Transcription elongation factor A protein-like 4 OS=Homo sapiens OX=9606 GN=TCEAL4 PE=1 SV=2 4.31 2970.1 - 716599 - - - -1.205 - 2.711 0.465 - 358.5 1 2 0 -0.0022 15 0 0 0 5.39E+06 3.39E+06 - - - 6.3261 1 221125_WJC_METTL3_EV_vs_WT_F04.17173.17173.3 8.33E-11 14/52 R.SDSFENPVLQQHFR[166.11].N "sp|P12956|XRCC6_HUMAN,tr|B1AHC9|B1AHC9_HUMAN" 2 1712.8146 1.37 50818 17173 3 1712.815956 571.9455 X-ray repair cross-complementing protein 6 OS=Homo sapiens OX=9606 GN=XRCC6 PE=1 SV=2 5.3 2970.4 - 614201 - - - 0.7899 - 3.194 0.608 - 325.9 1 2 0 0.0014 14 0 0 0 1.81E+08 1.32E+08 - - - 8.4043 0.9999 221125_WJC_METTL3_EV_vs_WT_F04.17174.17174.3 4.94E-05 15/40 K.TGPNLHGLFGR[166.11].K "sp|P99999|CYC_HUMAN,tr|C9JFR7|C9JFR7_HUMAN" 2 1177.6232 1.64 50819 17174 3 1177.621222 393.5483 Cytochrome c OS=Homo sapiens OX=9606 GN=CYCS PE=1 SV=2 9.44 2970.5 - 613589 - - - -1.6465 - 2.562 0.389 - 475.1 1 2 0 -0.0019 11 0 0 0 2.55E+07 1.55E+07 - - - 5.549 0.9995 221125_WJC_METTL3_EV_vs_WT_F04.17175.17175.2 6.33E-05 Sep-36 K.LLNGPGDVETGTSITVPQK[136.11].K "sp|Q9HC07|TM165_HUMAN,tr|V9GY93|V9GY93_HUMAN" 2 1933.0248 1.64 50820 17175 2 1933.019848 967.5197 Transmembrane protein 165 OS=Homo sapiens OX=9606 GN=TMEM165 PE=1 SV=1 4.37 2970.6 - 362722 - - - -2.5473 - 1.687 0.542 - 96.3 1 2 0 -0.0049 19 0 0 0 5.33E+06 3.25E+06 - - - 4.3284 0.9999 221125_WJC_METTL3_EV_vs_WT_F04.17176.17176.2 4.40E-06 13/26 R.TIQTPIGSTWNTQR[166.11].A "sp|Q5TAP6|UT14C_HUMAN,sp|Q9BVJ6|UT14A_HUMAN" 2 1611.8244 1.88 50821 17176 2 1611.82542 806.9195 U3 small nucleolar RNA-associated protein 14 homolog C OS=Homo sapiens OX=9606 GN=UTP14C PE=1 SV=1 9.41 2970.7 - 697821 - - - 0.6086 - 2.414 0.518 - 448.9 1 2 0 0.001 14 0 0 0 1.66E+07 8.86E+06 - - - 5.0782 0.9974 221125_WJC_METTL3_EV_vs_WT_F04.17178.17178.3 0.000632 Sep-44 K.EYRPETGSWVFK.V "sp|P52948|NUP98_HUMAN,tr|A0A3B3ITD8|A0A3B3ITD8_HUMAN" 2 1497.7252 1.73 50822 17178 3 1497.722596 500.249 Nuclear pore complex protein Nup98-Nup96 OS=Homo sapiens OX=9606 GN=NUP98 PE=1 SV=4 6.24 2971 - 2.78E+06 - - - -1.758 - 1.603 0.278 - 96.2 1 2 0 -0.0026 12 0 0 0 1.67E+08 9.65E+07 - - - 2.9467 1 221125_WJC_METTL3_EV_vs_WT_F04.17180.17180.3 7.71E-07 17/68 R.VAPEEHPVLLTEAPLNPK.A "sp|P63261|ACTG_HUMAN,sp|P60709|ACTB_HUMAN,tr|A0A804GS07|A0A804GS07_HUMAN,tr|I3L3I0|I3L3I0_HUMAN,tr|G5E9R0|G5E9R0_HUMAN,tr|E7EVS6|E7EVS6_HUMAN,tr|A0A6Q8PFE4|A0A6Q8PFE4_HUMAN,tr|J3KT65|J3KT65_HUMAN,tr|I3L3R2|I3L3R2_HUMAN,tr|K7EM38|K7EM38_HUMAN,tr|A0A6Q8PH58|A0A6Q8PH58_HUMAN,tr|I3L1U9|I3L1U9_HUMAN,tr|A0A2R8Y793|A0A2R8Y793_HUMAN,tr|I3L4N8|I3L4N8_HUMAN,tr|A0A2R8YGF8|A0A2R8YGF8_HUMAN" 15 1953.0571 1.16 50823 17180 3 1953.054143 652.0263 "Actin, cytoplasmic 2 OS=Homo sapiens OX=9606 GN=ACTG1 PE=1 SV=1" 4.75 2971.2 - 8.08E+06 - - - -1.5284 - 2.954 0.504 - 355.2 1 2 0 -0.003 18 0 0 0 2.93E+09 2.53E+09 - - - 6.8555 0.9999 221125_WJC_METTL3_EV_vs_WT_F04.17182.17182.3 8.71E-08 18/76 R.SLETENSALQLQVTEREEVR.G "sp|P20700|LMNB1_HUMAN,tr|A0A0D9SFY5|A0A0D9SFY5_HUMAN,tr|E9PBF6|E9PBF6_HUMAN,tr|A0A0D9SFE5|A0A0D9SFE5_HUMAN" 4 2330.1714 1.24 50825 17182 3 2330.174985 777.7311 Lamin-B1 OS=Homo sapiens OX=9606 GN=LMNB1 PE=1 SV=2 4.32 2971.3 - 3.01E+06 - - - 1.5458 - 3.187 0.516 - 323.9 1 2 1 0.0036 20 0 0 0 3.93E+07 3.16E+07 - - - 7.1038 0.9999 221125_WJC_METTL3_EV_vs_WT_F04.17183.17183.3 1.25E-07 13/48 K.IATEK[136.11]DFLEAVNK[136.11].V "sp|P35998|PRS7_HUMAN,tr|C9JX88|C9JX88_HUMAN" 2 1492.8108 0.72 50826 17183 3 1492.809593 498.6109 26S proteasome regulatory subunit 7 OS=Homo sapiens OX=9606 GN=PSMC2 PE=1 SV=3 4.68 2971.4 - 2.90E+06 - - - -0.8152 - 2.82 0.572 - 214.9 1 2 1 -0.0012 13 0 0 0 1.71E+07 2.37E+07 - - - 7.7278 0.9999 221125_WJC_METTL3_EV_vs_WT_F04.17184.17184.2 9.37E-06 14/24 K.DEILPTTPISEQK[136.11].G "sp|P23396|RS3_HUMAN,tr|H0YEU2|H0YEU2_HUMAN,tr|E9PSF4|E9PSF4_HUMAN,tr|E9PL09|E9PL09_HUMAN,tr|E9PPU1|E9PPU1_HUMAN" 5 1477.7755 0.77 50827 17184 2 1477.776074 739.895 40S ribosomal protein S3 OS=Homo sapiens OX=9606 GN=RPS3 PE=1 SV=2 4.14 2971.4 - 2.17E+06 - - - 0.3614 - 2.688 0.546 - 540.2 1 2 0 0.0005 13 0 0 0 1.17E+09 1.52E+09 - - - 5.6114 0.9999 221125_WJC_METTL3_EV_vs_WT_F04.17185.17185.3 0.000176 Dec-40 K.TGPNLHGLFGR.K "sp|P99999|CYC_HUMAN,tr|C9JFR7|C9JFR7_HUMAN" 2 1167.6149 1.64 50828 17185 3 1167.612384 390.2122 Cytochrome c OS=Homo sapiens OX=9606 GN=CYCS PE=1 SV=2 9.44 2971.5 - 2.07E+06 - - - -2.1471 - 2.372 0.471 - 198.5 1 2 0 -0.0025 11 0 0 0 2.55E+07 1.55E+07 - - - 6.2442 0.9951 221125_WJC_METTL3_EV_vs_WT_F04.17186.17186.3 1.97E-05 Nov-36 R.FDVQLKDLEK.W "sp|P62244|RS15A_HUMAN,tr|I3L3P7|I3L3P7_HUMAN,tr|H3BVC7|H3BVC7_HUMAN" 3 1233.6605 1.03 50829 17186 3 1233.658282 412.2274 40S ribosomal protein S15a OS=Homo sapiens OX=9606 GN=RPS15A PE=1 SV=2 4.56 2971.6 - 1.94E+06 - - - -1.8011 - 2.285 0.237 - 84.3 1 2 1 -0.0022 10 0 0 0 2.78E+07 2.71E+07 - - - 3.5951 1 221125_WJC_METTL3_EV_vs_WT_F04.17187.17187.3 2.32E-05 16/60 K.EGK[136.11]PTIVEEDDPELFK[136.11].Q sp|O75937|DNJC8_HUMAN 1 1860.9328 0.45 50830 17187 3 1860.931154 621.3182 DnaJ homolog subfamily C member 8 OS=Homo sapiens OX=9606 GN=DNAJC8 PE=1 SV=2 4.08 2971.7 - 1.77E+06 - - - -0.8711 - 2.768 0.524 - 313.1 1 2 0 -0.0016 16 0 0 0 7.11E+06 1.60E+07 - - - 6.994 1 221125_WJC_METTL3_EV_vs_WT_F04.17188.17188.2 3.24E-10 19/32 K.AEQINQAAGEASAVLAK[136.11].A "sp|Q9UJZ1|STML2_HUMAN,tr|A0A087WYB4|A0A087WYB4_HUMAN,tr|F2Z2I8|F2Z2I8_HUMAN" 3 1677.8777 57.37 50831 17188 2 1677.873914 839.9461 "Stomatin-like protein 2, mitochondrial OS=Homo sapiens OX=9606 GN=STOML2 PE=1 SV=1" 4.53 2971.8 - 1.72E+06 - - - -2.2648 - 4.186 0.619 - 999.1 1 2 0 -0.0038 17 0 0 0 1.59E+09 2.78E+07 - - - 7.1318 0.9999 221125_WJC_METTL3_EV_vs_WT_F04.17189.17189.3 1.24E-05 15/48 K.IATEKDFLEAVNK.V "sp|P35998|PRS7_HUMAN,tr|C9JX88|C9JX88_HUMAN" 2 1476.7824 0.71 50832 17189 3 1476.780814 493.2681 26S proteasome regulatory subunit 7 OS=Homo sapiens OX=9606 GN=PSMC2 PE=1 SV=3 4.68 2971.9 - 1.61E+06 - - - -1.0807 - 2.968 0.459 - 325.1 1 2 1 -0.0016 13 0 0 0 1.66E+07 2.35E+07 - - - 6.6065 1 221125_WJC_METTL3_EV_vs_WT_F04.17190.17190.3 2.70E-07 17/52 R.SDSFENPVLQQHFR.N "sp|P12956|XRCC6_HUMAN,tr|B1AHC9|B1AHC9_HUMAN" 2 1702.8063 1.37 50833 17190 3 1702.805208 568.6094 X-ray repair cross-complementing protein 6 OS=Homo sapiens OX=9606 GN=XRCC6 PE=1 SV=2 5.3 2972 - 1.57E+06 - - - -0.6607 - 3.468 0.64 - 587.2 1 2 0 -0.0011 14 0 0 0 1.83E+08 1.33E+08 - - - 8.9799 0.9996 221125_WJC_METTL3_EV_vs_WT_F04.17191.17191.2 0.00935 13/26 K.TVQGPPTSDDIFER.E sp|P04181|OAT_HUMAN 1 1560.742 0.99 50834 17191 2 1560.738501 781.3783 "Ornithine aminotransferase, mitochondrial OS=Homo sapiens OX=9606 GN=OAT PE=1 SV=1" 4.03 2972.1 - 1.12E+06 - - - -2.2425 - 2.424 0.448 - 502.3 1 2 0 -0.0035 14 0 0 0 1.77E+07 1.80E+07 - - - 4.5707 0.9966 221125_WJC_METTL3_EV_vs_WT_F04.17193.17193.3 0.000168 17/64 K.AEQINQAAGEASAVLAK[136.11].A "sp|Q9UJZ1|STML2_HUMAN,tr|A0A087WYB4|A0A087WYB4_HUMAN,tr|F2Z2I8|F2Z2I8_HUMAN" 3 1677.8777 13.63 50836 17193 3 1678.874942 560.2998 "Stomatin-like protein 2, mitochondrial OS=Homo sapiens OX=9606 GN=STOML2 PE=1 SV=1" 4.53 2972.3 - 1.06E+06 - - - 594.3389 - 3.604 0.5 - 581.2 1 2 0 0.9972 17 0 0 0 2.27E+08 1.67E+07 - - - 7.0771 1 221125_WJC_METTL3_EV_vs_WT_F04.17194.17194.2 1.39E-10 16/30 K.IFVGNVSAAC[160.03]TSQELR.S "sp|Q96PK6|RBM14_HUMAN,tr|B8ZZ74|B8ZZ74_HUMAN,tr|F8WDX3|F8WDX3_HUMAN,tr|A0A0A0MSL8|A0A0A0MSL8_HUMAN,tr|A0A0A6YYI9|A0A0A6YYI9_HUMAN" 5 1750.8672 2.76 50837 17194 2 1750.865474 876.4409 RNA-binding protein 14 OS=Homo sapiens OX=9606 GN=RBM14 PE=1 SV=2 5.99 2972.5 - 909566 - - - -0.9966 - 3.251 0.65 - 608 1 2 0 -0.0017 16 0 0 0 1.40E+07 5.08E+06 - - - 6.7399 1 221125_WJC_METTL3_EV_vs_WT_F04.17195.17195.3 1.54E-07 15/60 K.EGKPTIVEEDDPELFK.Q sp|O75937|DNJC8_HUMAN 1 1844.9044 0.45 50838 17195 3 1844.90437 615.9754 DnaJ homolog subfamily C member 8 OS=Homo sapiens OX=9606 GN=DNAJC8 PE=1 SV=2 4.08 2972.6 - 588064 - - - -0.0027 - 2.818 0.483 - 282.9 1 2 0 0 16 0 0 0 7.11E+06 1.60E+07 - - - 6.5833 0.9984 221125_WJC_METTL3_EV_vs_WT_F04.17196.17196.2 0.00176 Oct-32 R.SSTGPEPPAPTPLLAER[166.11].H "sp|Q9UQ35|SRRM2_HUMAN,tr|I3L1I8|I3L1I8_HUMAN,tr|I3L4D8|I3L4D8_HUMAN,tr|I3L182|I3L182_HUMAN" 4 1728.8922 0.73 50839 17196 2 1728.889428 865.4534 Serine\arginine repetitive matrix protein 2 OS=Homo sapiens OX=9606 GN=SRRM2 PE=1 SV=2 4.53 2972.7 - 433270 - - - -1.5947 - 1.615 0.291 - 130.1 1 2 0 -0.0028 17 0 0 0 3.37E+06 4.63E+06 - - - 2.3679 0.9999 221125_WJC_METTL3_EV_vs_WT_F04.17200.17200.3 9.71E-05 13/56 K.FGQGDLPKPINSDFR.S sp|P49792|RBP2_HUMAN 1 1689.8475 0.78 50842 17200 3 1689.84393 564.2898 E3 SUMO-protein ligase RanBP2 OS=Homo sapiens OX=9606 GN=RANBP2 PE=1 SV=2 5.96 2973.2 - 1.14E+06 - - - -2.0949 - 2.122 0.475 - 128.3 1 2 0 -0.0035 15 0 0 0 9.98E+06 1.27E+07 - - - 5.798 0.9999 221125_WJC_METTL3_EV_vs_WT_F04.17202.17202.2 0.000175 24-Dec K.DEILPTTPISEQK.G "sp|P23396|RS3_HUMAN,tr|H0YEU2|H0YEU2_HUMAN,tr|E9PSF4|E9PSF4_HUMAN,tr|E9PL09|E9PL09_HUMAN,tr|E9PPU1|E9PPU1_HUMAN" 5 1469.7613 0.77 50844 17202 2 1469.760313 735.8879 40S ribosomal protein S3 OS=Homo sapiens OX=9606 GN=RPS3 PE=1 SV=2 4.14 2973.4 - 5.23E+06 - - - -0.6988 - 2.073 0.546 - 379.5 1 2 0 -0.001 13 0 0 0 1.17E+09 1.52E+09 - - - 4.9444 0.9996 221125_WJC_METTL3_EV_vs_WT_F04.17203.17203.3 0.0001 Oct-32 R.FSFWDKDAR.T "sp|P78406|RAE1L_HUMAN,tr|E9PQ57|E9PQ57_HUMAN" 2 1170.5458 1.59 50845 17203 3 1170.54414 391.1892 mRNA export factor OS=Homo sapiens OX=9606 GN=RAE1 PE=1 SV=1 5.96 2973.4 - 4.61E+06 - - - -1.425 - 1.984 0.443 - 124 1 2 1 -0.0017 9 0 0 0 5.72E+07 3.60E+07 - - - 5.5433 1 221125_WJC_METTL3_EV_vs_WT_F04.17204.17204.2 3.31E-09 14/28 K.NQVALNPQNTVFDAK.R "sp|P0DMV8|HS71A_HUMAN,sp|P0DMV9|HS71B_HUMAN,tr|A0A0G2JIW1|A0A0G2JIW1_HUMAN" 3 1657.8424 0.16 50846 17204 2 1657.841981 829.9285 Heat shock 70 kDa protein 1A OS=Homo sapiens OX=9606 GN=HSPA1A PE=1 SV=1 5.84 2973.5 - 4.26E+06 - - - -0.2431 - 2.931 0.646 - 506.8 1 2 0 -0.0004 15 0 0 0 2.21E+09 1.41E+10 - - - 6.456 1 221125_WJC_METTL3_EV_vs_WT_F04.17206.17206.3 5.71E-15 22/68 K.FYC[160.03]DYC[160.03]DTYLTHDSPSVR[166.11].K "sp|P09234|RU1C_HUMAN,tr|A0A0A0MRR7|A0A0A0MRR7_HUMAN" 2 2307.944 1.05 50848 17206 3 2307.942803 770.322 U1 small nuclear ribonucleoprotein C OS=Homo sapiens OX=9606 GN=SNRPC PE=1 SV=1 4.41 2973.6 - 2.28E+06 - - - -0.5355 - 3.561 0.772 - 560.1 1 2 0 -0.0012 18 0 0 0 6.31E+07 6.04E+07 - - - 10.3092 0.9987 221125_WJC_METTL3_EV_vs_WT_F04.17209.17209.2 1.48E-06 Nov-36 K.INTLKEENTQEAAVLNGVS.- "sp|P51114|FXR1_HUMAN,tr|B4DXZ6|B4DXZ6_HUMAN" 2 2029.0328 2.42 50851 17209 2 2029.032951 1015.5237 Fragile X mental retardation syndrome-related protein 1 OS=Homo sapiens OX=9606 GN=FXR1 PE=1 SV=3 4.25 2974 - 928726 - - - 0.0922 - 2.422 0.513 - 266 1 2 1 0.0002 19 0 0 0 8.09E+06 3.34E+06 - - - 5.0048 1 221125_WJC_METTL3_EV_vs_WT_F04.17211.17211.2 1.30E-09 15/30 K.IFVGNVSAAC[160.03]TSQELR[166.11].S "sp|Q96PK6|RBM14_HUMAN,tr|B8ZZ74|B8ZZ74_HUMAN,tr|F8WDX3|F8WDX3_HUMAN,tr|A0A0A0MSL8|A0A0A0MSL8_HUMAN,tr|A0A0A6YYI9|A0A0A6YYI9_HUMAN" 5 1760.8755 2.76 50853 17211 2 1760.877043 881.445 RNA-binding protein 14 OS=Homo sapiens OX=9606 GN=RBM14 PE=1 SV=2 5.99 2974.2 - 613152 - - - 0.8825 - 2.596 0.619 - 333.2 1 2 0 0.0016 16 0 0 0 1.40E+07 5.08E+06 - - - 5.9578 1 221125_WJC_METTL3_EV_vs_WT_F04.17216.17216.3 0.0264 15/68 K.AFGSGIDIK[136.11]PGTPPIAGR[166.11].S "sp|Q9Y520|PRC2C_HUMAN,tr|E7EPN9|E7EPN9_HUMAN,tr|A0A2R8Y424|A0A2R8Y424_HUMAN,tr|H7C5N8|H7C5N8_HUMAN,tr|A0A2R8Y7F4|A0A2R8Y7F4_HUMAN,tr|A0A2R8YET2|A0A2R8YET2_HUMAN" 6 1770.9747 3.06 50856 17216 3 1770.974718 591.3322 Protein PRRC2C OS=Homo sapiens OX=9606 GN=PRRC2C PE=1 SV=4 8.79 2974.8 - 2.28E+06 - - - -0.0119 - 2.687 0.452 - 216.6 1 2 0 0 18 0 0 0 1.40E+08 4.58E+07 - - - 6.0406 1 221125_WJC_METTL3_EV_vs_WT_F04.17219.17219.3 1.22E-07 15/56 K.NQVALNPQNTVFDAK.R "sp|P0DMV8|HS71A_HUMAN,sp|P0DMV9|HS71B_HUMAN,tr|A0A0G2JIW1|A0A0G2JIW1_HUMAN" 3 1657.8424 0.16 50859 17219 3 1657.842901 553.6214 Heat shock 70 kDa protein 1A OS=Homo sapiens OX=9606 GN=HSPA1A PE=1 SV=1 5.84 2975.1 - 1.59E+06 - - - 0.3119 - 3.108 0.534 - 383.5 1 2 0 0.0005 15 0 0 0 2.86E+08 1.79E+09 - - - 7.4524 0.9988 221125_WJC_METTL3_EV_vs_WT_F04.17221.17221.3 0.00054 Dec-52 R.LREMFGLYGQTTGK.G "sp|Q9Y6B6|SAR1B_HUMAN,tr|D6RD69|D6RD69_HUMAN,tr|D6R9R5|D6R9R5_HUMAN,tr|Q9H029|Q9H029_HUMAN" 4 1599.8079 2.05 50861 17221 3 1599.80702 534.2766 GTP-binding protein SAR1b OS=Homo sapiens OX=9606 GN=SAR1B PE=1 SV=1 8.59 2975.3 - 948214 - - - -0.5582 - 1.984 0.354 - 101 1 2 1 -0.0009 14 0 0 0 6.53E+07 3.18E+07 - - - 4.3072 0.9999 221125_WJC_METTL3_EV_vs_WT_F04.17224.17224.2 0.000325 13/26 K.TVQGPPTSDDIFER[166.11].E sp|P04181|OAT_HUMAN 1 1570.7503 0.99 50864 17224 2 1570.748383 786.3824 "Ornithine aminotransferase, mitochondrial OS=Homo sapiens OX=9606 GN=OAT PE=1 SV=1" 4.03 2975.6 - 783120 - - - -1.202 - 2.509 0.505 - 422.8 1 2 0 -0.0019 14 0 0 0 1.77E+07 1.80E+07 - - - 5.0787 0.9988 221125_WJC_METTL3_EV_vs_WT_F04.17225.17225.3 3.08E-07 18/52 A.TSTASTFVK[136.11]PIFSR[166.11].D "sp|P56556|NDUA6_HUMAN,tr|A0A2Y9D025|A0A2Y9D025_HUMAN" 2 1558.8474 1.66 50865 17225 3 1558.849142 520.6231 NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 6 OS=Homo sapiens OX=9606 GN=NDUFA6 PE=1 SV=4 11 2975.8 - 752889 - - - 1.1092 - 2.961 0.624 - 448.2 1 1 0 0.0017 14 0 0 0 1.19E+07 7.20E+06 - - - 8.3813 0.9997 221125_WJC_METTL3_EV_vs_WT_F04.17227.17227.2 1.34E-06 15/26 K.QIGNVAALPGIVHR.S sp|Q9Y3I0|RTCB_HUMAN 1 1443.831 2.06 50867 17227 2 1443.833877 722.9228 RNA-splicing ligase RtcB homolog OS=Homo sapiens OX=9606 GN=RTCB PE=1 SV=1 9.76 2976 - 668600 - - - 1.9705 - 2.647 0.458 - 787.9 1 2 0 0.0028 14 0 0 0 7.24E+06 3.52E+06 - - - 4.8657 1 221125_WJC_METTL3_EV_vs_WT_F04.17231.17231.3 4.40E-10 16/56 K.VIEHIMEDLDTNADK.Q sp|P06702|S10A9_HUMAN 1 1741.8193 213.91 50870 17231 3 1741.817952 581.6137 Protein S100-A9 OS=Homo sapiens OX=9606 GN=S100A9 PE=1 SV=1 4.1 2976.5 - 1.44E+07 - - - -0.7544 - 3.292 0.664 - 482.3 1 2 0 -0.0013 15 0 0 0 2.28E+08 1.07E+06 - - - 9.0516 0.9999 221125_WJC_METTL3_EV_vs_WT_F04.17233.17233.3 3.83E-07 Nov-56 K.NQVALNPQNTVFDAK[136.11].R "sp|P0DMV8|HS71A_HUMAN,sp|P0DMV9|HS71B_HUMAN,tr|A0A0G2JIW1|A0A0G2JIW1_HUMAN" 3 1665.8566 0.16 50871 17233 3 1665.854635 556.2928 Heat shock 70 kDa protein 1A OS=Homo sapiens OX=9606 GN=HSPA1A PE=1 SV=1 5.84 2976.7 - 1.76E+07 - - - -1.17 - 2.65 0.436 - 172.2 1 2 0 -0.0019 15 0 0 0 2.88E+08 1.79E+09 - - - 5.9434 1 221125_WJC_METTL3_EV_vs_WT_F04.17234.17234.2 6.34E-07 15/26 R.AGGIETIANEYSDR[166.11].C "sp|P34932|HSP74_HUMAN,tr|A0A087WTS8|A0A087WTS8_HUMAN,tr|A0A087WYC1|A0A087WYC1_HUMAN" 3 1504.7033 0.09 50872 17234 2 1504.70118 753.3589 Heat shock 70 kDa protein 4 OS=Homo sapiens OX=9606 GN=HSPA4 PE=1 SV=4 4.14 2976.8 - 2.09E+06 - - - -1.4229 - 2.802 0.583 - 908.7 1 2 0 -0.0021 14 0 0 0 3.41E+07 3.65E+08 - - - 5.9319 0.9996 221125_WJC_METTL3_EV_vs_WT_F04.17235.17235.3 7.32E-06 Dec-52 R.LR[166.11]EMFGLYGQTTGK[136.11].G "sp|Q9Y6B6|SAR1B_HUMAN,tr|D6RD69|D6RD69_HUMAN,tr|D6R9R5|D6R9R5_HUMAN,tr|Q9H029|Q9H029_HUMAN" 4 1617.8304 1.99 50873 17235 3 1617.828296 540.2841 GTP-binding protein SAR1b OS=Homo sapiens OX=9606 GN=SAR1B PE=1 SV=1 8.59 2976.9 - 1.84E+06 - - - -1.29 - 2.416 0.416 - 176.2 1 2 1 -0.0021 14 0 0 0 6.44E+07 3.23E+07 - - - 5.5217 0.9998 221125_WJC_METTL3_EV_vs_WT_F04.17237.17237.3 3.75E-05 16/48 K.ATLPSPDK[136.11]LPGFK[136.11].M "sp|P22314|UBA1_HUMAN,tr|Q5JRR6|Q5JRR6_HUMAN" 2 1385.789 0.56 50875 17237 3 1385.787867 462.9369 Ubiquitin-like modifier-activating enzyme 1 OS=Homo sapiens OX=9606 GN=UBA1 PE=1 SV=3 8.64 2977.2 - 951764 - - - -0.7829 - 2.933 0.428 - 498.4 1 2 1 -0.0011 13 0 0 0 2.58E+07 4.59E+07 - - - 6.2289 0.9982 221125_WJC_METTL3_EV_vs_WT_F04.17246.17246.3 0.000675 Oct-32 R.FSFWDK[136.11]DAR[166.11].T "sp|P78406|RAE1L_HUMAN,tr|E9PQ57|E9PQ57_HUMAN" 2 1188.5683 1.59 50883 17246 3 1188.56552 397.1967 mRNA export factor OS=Homo sapiens OX=9606 GN=RAE1 PE=1 SV=1 5.96 2978.3 - 2.39E+06 - - - -2.3204 - 1.898 0.377 - 88.1 1 2 1 -0.0028 9 0 0 0 5.71E+07 3.60E+07 - - - 4.6737 1 221125_WJC_METTL3_EV_vs_WT_F04.17249.17249.3 2.79E-10 20/76 K.VNNSSLIGVGYTQTLRPGVK.L "sp|P45880|VDAC2_HUMAN,tr|A0A0A0MR02|A0A0A0MR02_HUMAN" 2 2102.1484 1.45 50885 17249 3 2102.145754 701.7234 Voltage-dependent anion-selective channel protein 2 OS=Homo sapiens OX=9606 GN=VDAC2 PE=1 SV=2 9.99 2978.6 - 2.11E+06 - - - -1.2601 - 4.075 0.616 - 540.7 1 2 0 -0.0026 20 0 0 0 1.05E+08 7.23E+07 - - - 8.8153 1 221125_WJC_METTL3_EV_vs_WT_F04.17250.17250.3 2.73E-15 23/68 K.FYC[160.03]DYC[160.03]DTYLTHDSPSVR.K "sp|P09234|RU1C_HUMAN,tr|A0A0A0MRR7|A0A0A0MRR7_HUMAN" 2 2297.9358 1.05 50886 17250 3 2297.931558 766.9859 U1 small nuclear ribonucleoprotein C OS=Homo sapiens OX=9606 GN=SNRPC PE=1 SV=1 4.41 2978.6 - 5.52E+06 - - - -1.8325 - 3.88 0.659 - 666 1 2 0 -0.0042 18 0 0 0 6.31E+07 6.04E+07 - - - 9.2622 1 221125_WJC_METTL3_EV_vs_WT_F04.17252.17252.3 1.52E-08 23/76 K.VNNSSLIGVGYTQTLR[166.11]PGVK[136.11].L "sp|P45880|VDAC2_HUMAN,tr|A0A0A0MR02|A0A0A0MR02_HUMAN" 2 2120.1709 1.45 50888 17252 3 2120.168611 707.7309 Voltage-dependent anion-selective channel protein 2 OS=Homo sapiens OX=9606 GN=VDAC2 PE=1 SV=2 9.99 2978.8 - 2.11E+06 - - - -1.0669 - 4.1 0.613 - 752.8 1 2 0 -0.0023 20 0 0 0 1.05E+08 7.23E+07 - - - 8.7968 1 221125_WJC_METTL3_EV_vs_WT_F04.17253.17253.2 3.95E-08 20/34 R.VAPEEHPVLLTEAPLNPK[136.11].A "sp|P63261|ACTG_HUMAN,sp|P60709|ACTB_HUMAN,tr|A0A804GS07|A0A804GS07_HUMAN,tr|I3L3I0|I3L3I0_HUMAN,tr|G5E9R0|G5E9R0_HUMAN,tr|E7EVS6|E7EVS6_HUMAN,tr|A0A6Q8PFE4|A0A6Q8PFE4_HUMAN,tr|J3KT65|J3KT65_HUMAN,tr|I3L3R2|I3L3R2_HUMAN,tr|K7EM38|K7EM38_HUMAN,tr|A0A6Q8PH58|A0A6Q8PH58_HUMAN,tr|I3L1U9|I3L1U9_HUMAN,tr|A0A2R8Y793|A0A2R8Y793_HUMAN,tr|I3L4N8|I3L4N8_HUMAN,tr|A0A2R8YGF8|A0A2R8YGF8_HUMAN" 15 1961.0713 1.12 50889 17253 2 1961.069283 981.5429 "Actin, cytoplasmic 2 OS=Homo sapiens OX=9606 GN=ACTG1 PE=1 SV=1" 4.75 2978.9 - 1.16E+06 - - - -1.0428 - 3.934 0.69 - 905.2 1 2 0 -0.002 18 0 0 0 6.90E+07 6.15E+07 - - - 7.5041 0.9981 221125_WJC_METTL3_EV_vs_WT_F04.17254.17254.3 0.00212 Oct-40 K.IHPQTIIAGWR[166.11].E "sp|P78371|TCPB_HUMAN,tr|F8VQ14|F8VQ14_HUMAN,tr|F5GWF6|F5GWF6_HUMAN" 3 1300.728 0.37 50890 17254 3 1300.725659 434.5833 T-complex protein 1 subunit beta OS=Homo sapiens OX=9606 GN=CCT2 PE=1 SV=4 9.76 2979 - 1.12E+06 - - - -1.769 - 2.1 0.224 - 211 1 2 0 -0.0023 11 0 0 0 8.53E+06 2.28E+07 - - - 3.1445 0.9999 221125_WJC_METTL3_EV_vs_WT_F04.17255.17255.2 1.15E-07 13/24 R.SSFYSLTSSNISK.W sp|Q8WUM0|NU133_HUMAN 1 1419.6882 1.88 50891 17255 2 1419.686049 710.8514 Nuclear pore complex protein Nup133 OS=Homo sapiens OX=9606 GN=NUP133 PE=1 SV=2 8.31 2979.2 - 1.05E+06 - - - -1.4975 - 2.491 0.579 - 395.3 1 2 0 -0.0021 13 0 0 0 2.77E+07 1.48E+07 - - - 5.6593 0.9984 221125_WJC_METTL3_EV_vs_WT_F04.17256.17256.3 0.0437 13/48 R.VQGFQVEYKDFPK.N "sp|O95793|STAU1_HUMAN,tr|Q5JW30|Q5JW30_HUMAN" 2 1583.7984 2.74 50892 17256 3 1583.79975 528.9401 Double-stranded RNA-binding protein Staufen homolog 1 OS=Homo sapiens OX=9606 GN=STAU1 PE=1 SV=2 6.04 2979.3 - 595654 - - - 0.8562 - 2.336 0.294 - 122.1 1 2 1 0.0014 13 0 0 0 4.52E+07 1.65E+07 - - - 4.1178 1 221125_WJC_METTL3_EV_vs_WT_F04.17257.17257.2 1.27E-06 16/30 R.AADEEAFEDNSEEYIR[166.11].R sp|P55060|XPO2_HUMAN 1 1896.7889 1.14 50893 17257 2 1896.788346 949.4017 Exportin-2 OS=Homo sapiens OX=9606 GN=CSE1L PE=1 SV=3 3.71 2979.4 - 551030 - - - -0.2926 - 3.679 0.666 - 902.9 1 2 0 -0.0006 16 0 0 0 3.44E+07 3.01E+07 - - - 7.1625 0.9999 221125_WJC_METTL3_EV_vs_WT_F04.17258.17258.2 2.49E-09 26-Dec R.SDSFENPVLQQHFR.N "sp|P12956|XRCC6_HUMAN,tr|B1AHC9|B1AHC9_HUMAN" 2 1702.8063 1.69 50894 17258 2 1702.804714 852.4104 X-ray repair cross-complementing protein 6 OS=Homo sapiens OX=9606 GN=XRCC6 PE=1 SV=2 5.3 2979.6 - 381753 - - - -0.9508 - 2.66 0.514 - 424.6 1 2 0 -0.0016 14 0 0 0 1.14E+07 6.74E+06 - - - 5.292 1 221125_WJC_METTL3_EV_vs_WT_F04.17264.17264.2 9.73E-13 19/30 R.AADEEAFEDNSEEYIR.R sp|P55060|XPO2_HUMAN 1 1886.7806 1.15 50898 17264 2 1886.780072 944.3976 Exportin-2 OS=Homo sapiens OX=9606 GN=CSE1L PE=1 SV=3 3.71 2980.3 - 1.11E+06 - - - -0.2963 - 3.919 0.77 - 1551.2 1 2 0 -0.0006 16 0 0 0 3.46E+07 3.01E+07 - - - 8.086 0.9997 221125_WJC_METTL3_EV_vs_WT_F04.17265.17265.2 1.41E-05 13/24 R.SSLQSQC[160.03]LNEVLK[136.11].A "sp|Q14204|DYHC1_HUMAN,tr|A0A7P0T8N2|A0A7P0T8N2_HUMAN,tr|A0A7P0T9C4|A0A7P0T9C4_HUMAN,tr|A0A7P0TBJ7|A0A7P0TBJ7_HUMAN,tr|A0A7P0T9K2|A0A7P0T9K2_HUMAN,tr|A0A2R8Y706|A0A2R8Y706_HUMAN,tr|A0A7P0T916|A0A7P0T916_HUMAN,tr|A0A7P0TB75|A0A7P0TB75_HUMAN,tr|A0A7P0TAF3|A0A7P0TAF3_HUMAN,tr|A0A7P0T9F1|A0A7P0T9F1_HUMAN,tr|A0A7P0TAW9|A0A7P0TAW9_HUMAN,tr|A0A7P0TA13|A0A7P0TA13_HUMAN,tr|A0A7P0T7V5|A0A7P0T7V5_HUMAN,tr|A0A7P0T9R4|A0A7P0T9R4_HUMAN,tr|A0A2R8Y5T0|A0A2R8Y5T0_HUMAN,tr|A0A2R8Y6H2|A0A2R8Y6H2_HUMAN" 16 1512.7697 0.2 50899 17265 2 1512.765557 757.3921 Cytoplasmic dynein 1 heavy chain 1 OS=Homo sapiens OX=9606 GN=DYNC1H1 PE=1 SV=5 5.72 2980.4 - 1.05E+06 - - - -2.7671 - 2.549 0.565 - 692.2 1 2 0 -0.0042 13 0 0 0 3.24E+06 1.62E+07 - - - 5.6143 1 221125_WJC_METTL3_EV_vs_WT_F04.17266.17266.2 2.24E-08 13/24 R.SQGC[160.03]SEQVLTVLK[136.11].T sp|P78527|PRKDC_HUMAN 1 1455.7483 0.6 50900 17266 2 1455.74313 728.8814 DNA-dependent protein kinase catalytic subunit OS=Homo sapiens OX=9606 GN=PRKDC PE=1 SV=3 5.72 2980.5 - 854940 - - - -3.537 - 2.724 0.63 - 628.3 1 2 0 -0.0051 13 0 0 0 9.32E+06 1.55E+07 - - - 6.2645 0.9976 221125_WJC_METTL3_EV_vs_WT_F04.17267.17267.2 0.105 16-Nov R.AGLQFPVGR[166.11].V "sp|P16104|H2AX_HUMAN,sp|Q9BTM1|H2AJ_HUMAN,sp|Q93077|H2A1C_HUMAN,sp|Q99878|H2A1J_HUMAN,sp|Q16777|H2A2C_HUMAN,sp|Q8IUE6|H2A2B_HUMAN,sp|Q96QV6|H2A1A_HUMAN,sp|P0C0S5|H2AZ_HUMAN,sp|P04908|H2A1B_HUMAN,sp|P20671|H2A1D_HUMAN,sp|P0C0S8|H2A1_HUMAN,sp|Q6FI13|H2A2A_HUMAN,sp|Q96KK5|H2A1H_HUMAN,sp|Q71UI9|H2AV_HUMAN,sp|Q7L7L0|H2A3_HUMAN,tr|A0A0U1RR32|A0A0U1RR32_HUMAN,tr|A0A0U1RRH7|A0A0U1RRH7_HUMAN,tr|A0A3B3IS11|A0A3B3IS11_HUMAN,tr|C9J0D1|C9J0D1_HUMAN,tr|A0A494C189|A0A494C189_HUMAN" 20 953.5322 1.28 50901 17267 2 953.530927 477.7734 Histone H2AX OS=Homo sapiens OX=9606 GN=H2AX PE=1 SV=2 9.79 2980.6 - 682602 - - - -1.356 - 1.524 0.227 - 324.6 1 2 0 -0.0013 9 0 0 0 2.33E+07 1.81E+07 - - - 1.9362 1 221125_WJC_METTL3_EV_vs_WT_F04.17270.17270.3 4.83E-06 18/72 K.NLPPSGAVPVTGIPPHVVK[136.11].V "sp|Q13283|G3BP1_HUMAN,tr|A0A7I2V5M7|A0A7I2V5M7_HUMAN,tr|A0A7I2YQM1|A0A7I2YQM1_HUMAN,tr|A0A7P0P2U7|A0A7P0P2U7_HUMAN,tr|A0A7I2YQU8|A0A7I2YQU8_HUMAN,tr|A0A7I2V548|A0A7I2V548_HUMAN,tr|A0A7I2V651|A0A7I2V651_HUMAN,tr|A0A7I2V4D8|A0A7I2V4D8_HUMAN,tr|A0A7I2YQN9|A0A7I2YQN9_HUMAN" 9 1886.0869 1.35 50903 17270 3 1886.08364 629.7029 Ras GTPase-activating protein-binding protein 1 OS=Homo sapiens OX=9606 GN=G3BP1 PE=1 SV=1 8.76 2981 - 2.24E+06 - - - -1.738 - 2.627 0.536 - 298.5 1 2 0 -0.0033 19 0 0 0 1.05E+08 7.77E+07 - - - 6.8878 1 221125_WJC_METTL3_EV_vs_WT_F04.17272.17272.2 2.17E-06 14/26 R.AGGIETIANEYSDR.C "sp|P34932|HSP74_HUMAN,tr|A0A087WTS8|A0A087WTS8_HUMAN,tr|A0A087WYC1|A0A087WYC1_HUMAN" 3 1494.6951 0.09 50905 17272 2 1494.692763 748.3548 Heat shock 70 kDa protein 4 OS=Homo sapiens OX=9606 GN=HSPA4 PE=1 SV=4 4.14 2981.1 - 1.83E+06 - - - -1.5307 - 2.83 0.552 - 756.4 1 2 0 -0.0023 14 0 0 0 3.43E+07 3.65E+08 - - - 5.7279 0.9996 221125_WJC_METTL3_EV_vs_WT_F04.17274.17274.3 0.000112 14/48 K.ATLPSPDKLPGFK.M "sp|P22314|UBA1_HUMAN,tr|Q5JRR6|Q5JRR6_HUMAN" 2 1369.7606 0.55 50907 17274 3 1369.758227 457.5941 Ubiquitin-like modifier-activating enzyme 1 OS=Homo sapiens OX=9606 GN=UBA1 PE=1 SV=3 8.64 2981.4 - 926863 - - - -1.6974 - 2.625 0.407 - 354.2 1 2 1 -0.0023 13 0 0 0 2.52E+07 4.57E+07 - - - 5.6936 1 221125_WJC_METTL3_EV_vs_WT_F04.17279.17279.2 5.34E-12 24/34 R.VAPEEHPVLLTEAPLNPK.A "sp|P63261|ACTG_HUMAN,sp|P60709|ACTB_HUMAN,tr|A0A804GS07|A0A804GS07_HUMAN,tr|I3L3I0|I3L3I0_HUMAN,tr|G5E9R0|G5E9R0_HUMAN,tr|E7EVS6|E7EVS6_HUMAN,tr|A0A6Q8PFE4|A0A6Q8PFE4_HUMAN,tr|J3KT65|J3KT65_HUMAN,tr|I3L3R2|I3L3R2_HUMAN,tr|K7EM38|K7EM38_HUMAN,tr|A0A6Q8PH58|A0A6Q8PH58_HUMAN,tr|I3L1U9|I3L1U9_HUMAN,tr|A0A2R8Y793|A0A2R8Y793_HUMAN,tr|I3L4N8|I3L4N8_HUMAN,tr|A0A2R8YGF8|A0A2R8YGF8_HUMAN" 15 1953.0571 1.12 50910 17279 2 1953.054944 977.5358 "Actin, cytoplasmic 2 OS=Homo sapiens OX=9606 GN=ACTG1 PE=1 SV=1" 4.75 2982 - 1.80E+06 - - - -1.1182 - 4.267 0.564 - 1511.9 1 2 0 -0.0022 18 0 0 0 6.90E+07 6.15E+07 - - - 6.7731 0.9998 221125_WJC_METTL3_EV_vs_WT_F04.17282.17282.2 4.26E-05 24-Oct R.SQGC[160.03]SEQVLTVLK.T sp|P78527|PRKDC_HUMAN 1 1447.7341 0.59 50913 17282 2 1447.731346 724.8743 DNA-dependent protein kinase catalytic subunit OS=Homo sapiens OX=9606 GN=PRKDC PE=1 SV=3 5.72 2982.4 - 655008 - - - -1.8878 - 2.276 0.553 - 335.1 1 2 0 -0.0027 13 0 0 0 9.32E+06 1.59E+07 - - - 5.2354 1 221125_WJC_METTL3_EV_vs_WT_F04.17289.17289.3 2.54E-06 16/56 K.LQMEAPHIIVGTPGR.V "sp|P60842|IF4A1_HUMAN,tr|J3KTB5|J3KTB5_HUMAN,tr|J3KT12|J3KT12_HUMAN,tr|J3QKZ9|J3QKZ9_HUMAN,tr|J3QS69|J3QS69_HUMAN,tr|J3QL43|J3QL43_HUMAN,tr|J3KS25|J3KS25_HUMAN,tr|J3KSZ0|J3KSZ0_HUMAN,tr|J3QLN6|J3QLN6_HUMAN,tr|J3QR64|J3QR64_HUMAN" 10 1617.8661 0.91 50918 17289 3 1617.86285 540.296 Eukaryotic initiation factor 4A-I OS=Homo sapiens OX=9606 GN=EIF4A1 PE=1 SV=1 6.75 2983.2 - 1.65E+06 - - - -2.0063 - 2.734 0.507 - 301.7 1 2 0 -0.0032 15 0 0 0 8.20E+07 9.02E+07 - - - 6.8161 1 221125_WJC_METTL3_EV_vs_WT_F04.17291.17291.3 9.65E-10 16/56 K.NQVALNPQNTVFDAK[136.11].R "sp|P0DMV8|HS71A_HUMAN,sp|P0DMV9|HS71B_HUMAN,tr|A0A0G2JIW1|A0A0G2JIW1_HUMAN" 3 1665.8566 0.16 50919 17291 3 1665.853098 556.2928 Heat shock 70 kDa protein 1A OS=Homo sapiens OX=9606 GN=HSPA1A PE=1 SV=1 5.84 2983.4 - 6.89E+07 - - - -2.0926 - 3.109 0.561 - 452 1 2 0 -0.0035 15 0 0 0 2.88E+08 1.79E+09 - - - 7.7534 1 221125_WJC_METTL3_EV_vs_WT_F04.17295.17295.3 1.16E-09 31/60 A.PEEHPVLLTEAPLNPK.A "sp|P63261|ACTG_HUMAN,sp|P60709|ACTB_HUMAN,tr|A0A804GS07|A0A804GS07_HUMAN,tr|I3L3I0|I3L3I0_HUMAN,tr|G5E9R0|G5E9R0_HUMAN,tr|E7EVS6|E7EVS6_HUMAN,tr|A0A6Q8PFE4|A0A6Q8PFE4_HUMAN,tr|J3KT65|J3KT65_HUMAN,tr|I3L3R2|I3L3R2_HUMAN,tr|K7EM38|K7EM38_HUMAN,tr|A0A6Q8PH58|A0A6Q8PH58_HUMAN,tr|I3L1U9|I3L1U9_HUMAN,tr|A0A2R8Y793|A0A2R8Y793_HUMAN,tr|I3L4N8|I3L4N8_HUMAN,tr|A0A2R8YGF8|A0A2R8YGF8_HUMAN" 15 1782.9516 0.93 50922 17295 3 1782.953974 595.3245 "Actin, cytoplasmic 2 OS=Homo sapiens OX=9606 GN=ACTG1 PE=1 SV=1" 4.75 2983.9 - 777794 - - - 1.3315 - 4.647 0.677 - 1397.6 1 1 0 0.0024 16 0 0 0 1.82E+07 1.95E+07 - - - 10.029 0.9937 221125_WJC_METTL3_EV_vs_WT_F04.17303.17303.3 0.00212 13/40 K.K[136.11]LLHHLSDLAL.T "sp|Q86U44|MTA70_HUMAN,tr|B4E349|B4E349_HUMAN,tr|F5H6D8|F5H6D8_HUMAN,tr|H0YFV6|H0YFV6_HUMAN,tr|B4DTN4|B4DTN4_HUMAN" 5 1266.754 0.01 50928 17303 3 1266.75158 423.2586 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 6.92 2984.7 - 4.14E+06 - - - -1.8764 - 2.456 0.464 - 250.9 1 1 0 -0.0024 11 0 0 0 7.51E+05 1.42E+08 - - - 6.2651 0.9753 221125_WJC_METTL3_EV_vs_WT_F04.17309.17309.2 9.01E-06 28-Oct K.DHTPSQELALTQSVG.G "sp|Q86U44|MTA70_HUMAN,tr|H0YFV6|H0YFV6_HUMAN" 2 1581.7635 - 50932 17309 2 1581.760142 791.889 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 4.35 2985.5 - 3.17E+06 - - - -2.1008 - 1.997 0.47 - 317.1 1 1 0 -0.0033 15 0 0 0 - - - - - 4.2118 0.9999 221125_WJC_METTL3_EV_vs_WT_F04.17311.17311.2 5.15E-05 14/28 K.DAPPLLPSDTGQGYR[166.11].T "sp|Q9NPF5|DMAP1_HUMAN,tr|Q5TG39|Q5TG39_HUMAN,tr|Q5TG38|Q5TG38_HUMAN,tr|Q5TG40|Q5TG40_HUMAN,tr|Q5TG36|Q5TG36_HUMAN,tr|Q5TG37|Q5TG37_HUMAN" 6 1595.7819 1.62 50934 17311 2 1595.781873 798.8982 DNA methyltransferase 1-associated protein 1 OS=Homo sapiens OX=9606 GN=DMAP1 PE=1 SV=1 4.21 2985.8 - 1.64E+06 - - - -0.0207 - 2.128 0.521 - 356.2 1 2 0 0 15 0 0 0 7.70E+07 4.75E+07 - - - 4.7457 0.998 221125_WJC_METTL3_EV_vs_WT_F04.17312.17312.3 0.00134 14/40 K.EIKIEISELNR.V sp|P35908|K22E_HUMAN 1 1342.7456 999 50935 17312 3 1342.741654 448.5892 "Keratin, type II cytoskeletal 2 epidermal OS=Homo sapiens OX=9606 GN=KRT2 PE=1 SV=2" 4.79 2985.9 - 1.55E+06 - - - -2.9611 - 2.568 0.342 - 404.6 1 2 1 -0.004 11 0 0 0 7.77E+07 0.00E+00 - - - 5.0311 1 221125_WJC_METTL3_EV_vs_WT_F04.17313.17313.2 1.99E-10 17/30 K.VDATEESDLAQQYGVR[166.11].G "sp|P07237|PDIA1_HUMAN,tr|A0A7P0TA97|A0A7P0TA97_HUMAN,tr|A0A7P0T8C0|A0A7P0T8C0_HUMAN,tr|H7BZ94|H7BZ94_HUMAN,tr|A0A7P0TA71|A0A7P0TA71_HUMAN,tr|I3L4M2|I3L4M2_HUMAN,tr|A0A7P0T9D6|A0A7P0T9D6_HUMAN,tr|H0Y3Z3|H0Y3Z3_HUMAN,tr|A0A7P0Z4S2|A0A7P0Z4S2_HUMAN,tr|I3NI03|I3NI03_HUMAN,tr|A0A7P0TA35|A0A7P0TA35_HUMAN,tr|A0A7P0TAX9|A0A7P0TAX9_HUMAN,tr|I3L514|I3L514_HUMAN,tr|A0A7P0Z476|A0A7P0Z476_HUMAN,tr|A0A7P0TBP8|A0A7P0TBP8_HUMAN,tr|A0A7P0TB26|A0A7P0TB26_HUMAN,tr|A0A7P0T9U6|A0A7P0T9U6_HUMAN,tr|I3L0S0|I3L0S0_HUMAN,tr|I3L3P5|I3L3P5_HUMAN,tr|A0A7P0T8J3|A0A7P0T8J3_HUMAN,tr|A0A7P0Z4J0|A0A7P0Z4J0_HUMAN,tr|A0A7P0T9S9|A0A7P0T9S9_HUMAN,tr|A0A7P0T8X1|A0A7P0T8X1_HUMAN,tr|I3L3U6|I3L3U6_HUMAN" 24 1789.8358 1.37 50936 17313 2 1789.82933 895.9252 Protein disulfide-isomerase OS=Homo sapiens OX=9606 GN=P4HB PE=1 SV=3 3.92 2986.1 - 897078 - - - -3.6104 - 3.018 0.688 - 1001.8 1 2 0 -0.0065 16 0 0 0 1.26E+08 9.21E+07 - - - 6.8362 0.9721 221125_WJC_METTL3_EV_vs_WT_F04.17315.17315.2 5.61E-05 16-Sep N.PQNTVFDAK[136.11].R "sp|P0DMV8|HS71A_HUMAN,sp|P34931|HS71L_HUMAN,sp|P0DMV9|HS71B_HUMAN,tr|Q53FA3|Q53FA3_HUMAN,tr|A0A0G2JIW1|A0A0G2JIW1_HUMAN" 5 1026.5226 0.28 50938 17315 2 1026.519304 514.2686 Heat shock 70 kDa protein 1A OS=Homo sapiens OX=9606 GN=HSPA1A PE=1 SV=1 6.26 2986.3 - 748666 - - - -3.1719 - 2.364 0.519 - 385.8 1 1 0 -0.0033 9 0 0 0 5.34E+06 1.89E+07 - - - 5.3624 1 221125_WJC_METTL3_EV_vs_WT_F04.17319.17319.2 8.80E-13 20/30 K.VDATEESDLAQQYGVR.G "sp|P07237|PDIA1_HUMAN,tr|A0A7P0TA97|A0A7P0TA97_HUMAN,tr|A0A7P0T8C0|A0A7P0T8C0_HUMAN,tr|H7BZ94|H7BZ94_HUMAN,tr|A0A7P0TA71|A0A7P0TA71_HUMAN,tr|I3L4M2|I3L4M2_HUMAN,tr|A0A7P0T9D6|A0A7P0T9D6_HUMAN,tr|H0Y3Z3|H0Y3Z3_HUMAN,tr|A0A7P0Z4S2|A0A7P0Z4S2_HUMAN,tr|I3NI03|I3NI03_HUMAN,tr|A0A7P0TA35|A0A7P0TA35_HUMAN,tr|A0A7P0TAX9|A0A7P0TAX9_HUMAN,tr|I3L514|I3L514_HUMAN,tr|A0A7P0Z476|A0A7P0Z476_HUMAN,tr|A0A7P0TBP8|A0A7P0TBP8_HUMAN,tr|A0A7P0TB26|A0A7P0TB26_HUMAN,tr|A0A7P0T9U6|A0A7P0T9U6_HUMAN,tr|I3L0S0|I3L0S0_HUMAN,tr|I3L3P5|I3L3P5_HUMAN,tr|A0A7P0T8J3|A0A7P0T8J3_HUMAN,tr|A0A7P0Z4J0|A0A7P0Z4J0_HUMAN,tr|A0A7P0T9S9|A0A7P0T9S9_HUMAN,tr|A0A7P0T8X1|A0A7P0T8X1_HUMAN,tr|I3L3U6|I3L3U6_HUMAN" 24 1779.8275 1.37 50940 17319 2 1779.822357 890.921 Protein disulfide-isomerase OS=Homo sapiens OX=9606 GN=P4HB PE=1 SV=3 3.92 2986.8 - 2.06E+06 - - - -2.902 - 3.873 0.728 - 1781 1 2 0 -0.0052 16 0 0 0 1.26E+08 9.22E+07 - - - 7.7453 1 221125_WJC_METTL3_EV_vs_WT_F04.17320.17320.3 0.000105 18/60 K.VDATEESDLAQQYGVR.G "sp|P07237|PDIA1_HUMAN,tr|A0A7P0TA97|A0A7P0TA97_HUMAN,tr|A0A7P0T8C0|A0A7P0T8C0_HUMAN,tr|H7BZ94|H7BZ94_HUMAN,tr|A0A7P0TA71|A0A7P0TA71_HUMAN,tr|I3L4M2|I3L4M2_HUMAN,tr|A0A7P0T9D6|A0A7P0T9D6_HUMAN,tr|H0Y3Z3|H0Y3Z3_HUMAN,tr|A0A7P0Z4S2|A0A7P0Z4S2_HUMAN,tr|I3NI03|I3NI03_HUMAN,tr|A0A7P0TA35|A0A7P0TA35_HUMAN,tr|A0A7P0TAX9|A0A7P0TAX9_HUMAN,tr|I3L514|I3L514_HUMAN,tr|A0A7P0Z476|A0A7P0Z476_HUMAN,tr|A0A7P0TBP8|A0A7P0TBP8_HUMAN,tr|A0A7P0TB26|A0A7P0TB26_HUMAN,tr|A0A7P0T9U6|A0A7P0T9U6_HUMAN,tr|I3L0S0|I3L0S0_HUMAN,tr|I3L3P5|I3L3P5_HUMAN,tr|A0A7P0T8J3|A0A7P0T8J3_HUMAN,tr|A0A7P0Z4J0|A0A7P0Z4J0_HUMAN,tr|A0A7P0T9S9|A0A7P0T9S9_HUMAN,tr|A0A7P0T8X1|A0A7P0T8X1_HUMAN,tr|I3L3U6|I3L3U6_HUMAN" 24 1779.8275 1.52 50941 17320 3 1779.826648 594.2831 Protein disulfide-isomerase OS=Homo sapiens OX=9606 GN=P4HB PE=1 SV=3 3.92 2987 - 1.77E+06 - - - -0.4911 - 2.66 0.475 - 297 1 2 0 -0.0009 16 0 0 0 9.21E+07 6.07E+07 - - - 6.3458 0.9931 221125_WJC_METTL3_EV_vs_WT_F04.17322.17322.3 0.318 Sep-48 K.VKEGMNIVEAMER.F sp|P62937|PPIA_HUMAN 1 1504.7378 1.01 50943 17322 3 1504.73671 502.5865 Peptidyl-prolyl cis-trans isomerase A OS=Homo sapiens OX=9606 GN=PPIA PE=1 SV=2 4.79 2987.1 - 3.38E+06 - - - -0.7137 - 1.749 0.266 - 113.5 1 2 1 -0.0011 13 0 0 0 7.17E+07 7.09E+07 - - - 3.0211 0.9999 221125_WJC_METTL3_EV_vs_WT_F04.17324.17324.2 3.13E-08 24-Dec R.GLPWSC[160.03]SADEVQR[166.11].F "sp|P31943|HNRH1_HUMAN,tr|E7EQJ0|E7EQJ0_HUMAN,tr|D6R9D3|D6R9D3_HUMAN,tr|D6RIH9|D6RIH9_HUMAN,tr|D6RJ04|D6RJ04_HUMAN,tr|E5RGV0|E5RGV0_HUMAN,tr|D6RFM3|D6RFM3_HUMAN,tr|E9PCY7|E9PCY7_HUMAN,tr|D6RIT2|D6RIT2_HUMAN,tr|D6R9T0|D6R9T0_HUMAN,tr|D6RIU0|D6RIU0_HUMAN,tr|D6RAM1|D6RAM1_HUMAN,tr|D6RBM0|D6RBM0_HUMAN,tr|G8JLB6|G8JLB6_HUMAN,tr|D6RF17|D6RF17_HUMAN,tr|D6RDL0|D6RDL0_HUMAN,tr|D6RDU3|D6RDU3_HUMAN,tr|E7EN40|E7EN40_HUMAN" 18 1513.6859 1.09 50945 17324 2 1513.685354 757.8502 Heterogeneous nuclear ribonucleoprotein H OS=Homo sapiens OX=9606 GN=HNRNPH1 PE=1 SV=4 4.37 2987.2 - 2.07E+06 - - - -0.3587 - 2.182 0.623 - 423.9 1 2 0 -0.0005 13 0 0 0 7.16E+07 6.57E+07 - - - 5.6448 0.9999 221125_WJC_METTL3_EV_vs_WT_F04.17325.17325.2 0.000137 13/20 R.EQWEPVFQNGK.M "sp|Q14331|FRG1_HUMAN,tr|E9PRR7|E9PRR7_HUMAN" 2 1360.6412 1.04 50946 17325 2 1360.640357 681.3279 Protein FRG1 OS=Homo sapiens OX=9606 GN=FRG1 PE=1 SV=1 4.53 2987.4 - 1.25E+06 - - - -0.5938 - 2.262 0.517 - 586.4 1 2 0 -0.0008 11 0 0 0 3.10E+07 2.99E+07 - - - 5.0675 0.9999 221125_WJC_METTL3_EV_vs_WT_F04.17326.17326.2 0.000269 14/26 K.STPVTSAVQIPEVK.Q sp|Q96KR1|ZFR_HUMAN 1 1454.7981 1.22 50947 17326 2 1454.796717 728.4063 Zinc finger RNA-binding protein OS=Homo sapiens OX=9606 GN=ZFR PE=1 SV=2 5.72 2987.5 - 1.19E+06 - - - -0.9232 - 2.613 0.56 - 544.8 1 2 0 -0.0013 14 0 0 0 3.87E+07 3.16E+07 - - - 5.5871 0.9994 221125_WJC_METTL3_EV_vs_WT_F04.17329.17329.3 0.000118 Nov-48 K.VK[136.11]EGMNIVEAMER[166.11].F sp|P62937|PPIA_HUMAN 1 1522.7603 1.01 50948 17329 3 1522.757731 508.594 Peptidyl-prolyl cis-trans isomerase A OS=Homo sapiens OX=9606 GN=PPIA PE=1 SV=2 4.79 2987.9 - 5.03E+06 - - - -1.6569 - 2.065 0.434 - 180.7 1 2 1 -0.0025 13 0 0 0 7.18E+07 7.09E+07 - - - 5.344 1 221125_WJC_METTL3_EV_vs_WT_F04.17331.17331.3 2.22E-06 14/48 K.NC[160.03]LTNFHGMDLTR[166.11].D "sp|P61247|RS3A_HUMAN,tr|H0Y8L7|H0Y8L7_HUMAN,tr|D6RED7|D6RED7_HUMAN,tr|D6RAS7|D6RAS7_HUMAN,tr|D6RB09|D6RB09_HUMAN,tr|E9PFI5|E9PFI5_HUMAN,tr|D6RAT0|D6RAT0_HUMAN,tr|D6RG13|D6RG13_HUMAN" 8 1587.7162 0.81 50950 17331 3 1587.715076 530.246 40S ribosomal protein S3a OS=Homo sapiens OX=9606 GN=RPS3A PE=1 SV=2 6.74 2988 - 4.18E+06 - - - -0.6777 - 2.807 0.529 - 327.2 1 2 0 -0.0011 13 0 0 0 7.29E+07 8.96E+07 - - - 7.2359 1 221125_WJC_METTL3_EV_vs_WT_F04.17332.17332.3 0.000266 19/48 K.NC[160.03]LTNFHGMDLTR.D "sp|P61247|RS3A_HUMAN,tr|H0Y8L7|H0Y8L7_HUMAN,tr|D6RED7|D6RED7_HUMAN,tr|D6RAS7|D6RAS7_HUMAN,tr|D6RB09|D6RB09_HUMAN,tr|E9PFI5|E9PFI5_HUMAN,tr|D6RAT0|D6RAT0_HUMAN,tr|D6RG13|D6RG13_HUMAN" 8 1577.7079 0.81 50951 17332 3 1577.706623 526.9099 40S ribosomal protein S3a OS=Homo sapiens OX=9606 GN=RPS3A PE=1 SV=2 6.74 2988.1 - 2.68E+06 - - - -0.7974 - 3.151 0.522 - 721.6 1 2 0 -0.0013 13 0 0 0 7.29E+07 8.96E+07 - - - 7.4712 0.9998 221125_WJC_METTL3_EV_vs_WT_F04.17333.17333.2 5.75E-06 24-Dec R.YSSSSIPEPFGSR.G "sp|Q8WUF5|IASPP_HUMAN,tr|K7EN03|K7EN03_HUMAN" 2 1412.6572 2.8 50952 17333 2 1412.654469 707.3359 RelA-associated inhibitor OS=Homo sapiens OX=9606 GN=PPP1R13L PE=1 SV=4 6 2988.3 - 1.47E+06 - - - -1.9396 - 2.443 0.582 - 305.6 1 2 0 -0.0027 13 0 0 0 3.86E+07 1.38E+07 - - - 5.6313 1 221125_WJC_METTL3_EV_vs_WT_F04.17334.17334.2 2.96E-06 13/34 R.AIGGGLSSVGGGSSTIKY.T "sp|P48668|K2C6C_HUMAN,sp|P02538|K2C6A_HUMAN" 2 1609.8312 3.67 50953 17334 2 1609.828541 805.9229 "Keratin, type II cytoskeletal 6C OS=Homo sapiens OX=9606 GN=KRT6C PE=1 SV=3" 8.63 2988.4 - 814952 - - - -1.6213 - 2.759 0.578 - 353.6 1 1 0 -0.0026 18 0 0 0 1.62E+07 4.41E+06 - - - 5.8044 0.9951 221125_WJC_METTL3_EV_vs_WT_F04.17340.17340.3 0.000269 14/48 K.NREPLMPSPQFIK.S sp|O94826|TOM70_HUMAN 1 1555.8181 2.66 50957 17340 3 1555.8129 519.6133 Mitochondrial import receptor subunit TOM70 OS=Homo sapiens OX=9606 GN=TOMM70 PE=1 SV=1 8.75 2989.1 - 829423 - - - -3.332 - 1.899 0.376 - 200.7 1 2 1 -0.0052 13 0 0 0 2.30E+07 8.62E+06 - - - 4.4694 0.9999 221125_WJC_METTL3_EV_vs_WT_F04.17341.17341.3 2.31E-05 15/60 K.VDATEESDLAQQYGVR[166.11].G "sp|P07237|PDIA1_HUMAN,tr|A0A7P0TA97|A0A7P0TA97_HUMAN,tr|A0A7P0T8C0|A0A7P0T8C0_HUMAN,tr|H7BZ94|H7BZ94_HUMAN,tr|A0A7P0TA71|A0A7P0TA71_HUMAN,tr|I3L4M2|I3L4M2_HUMAN,tr|A0A7P0T9D6|A0A7P0T9D6_HUMAN,tr|H0Y3Z3|H0Y3Z3_HUMAN,tr|A0A7P0Z4S2|A0A7P0Z4S2_HUMAN,tr|I3NI03|I3NI03_HUMAN,tr|A0A7P0TA35|A0A7P0TA35_HUMAN,tr|A0A7P0TAX9|A0A7P0TAX9_HUMAN,tr|I3L514|I3L514_HUMAN,tr|A0A7P0Z476|A0A7P0Z476_HUMAN,tr|A0A7P0TBP8|A0A7P0TBP8_HUMAN,tr|A0A7P0TB26|A0A7P0TB26_HUMAN,tr|A0A7P0T9U6|A0A7P0T9U6_HUMAN,tr|I3L0S0|I3L0S0_HUMAN,tr|I3L3P5|I3L3P5_HUMAN,tr|A0A7P0T8J3|A0A7P0T8J3_HUMAN,tr|A0A7P0Z4J0|A0A7P0Z4J0_HUMAN,tr|A0A7P0T9S9|A0A7P0T9S9_HUMAN,tr|A0A7P0T8X1|A0A7P0T8X1_HUMAN,tr|I3L3U6|I3L3U6_HUMAN" 24 1789.8358 1.52 50958 17341 3 1789.833714 597.6192 Protein disulfide-isomerase OS=Homo sapiens OX=9606 GN=P4HB PE=1 SV=3 3.92 2989.1 - 3.43E+06 - - - -1.161 - 2.62 0.413 - 218.9 1 2 0 -0.0021 16 0 0 0 9.21E+07 6.07E+07 - - - 5.6153 1 221125_WJC_METTL3_EV_vs_WT_F04.17342.17342.2 1.78E-12 19/34 A.FASSLVSGLNSSASEPAK[136.11].E "sp|Q86U44|MTA70_HUMAN,tr|F5H6D8|F5H6D8_HUMAN,tr|H0YFV6|H0YFV6_HUMAN,tr|B4DTN4|B4DTN4_HUMAN" 4 1758.8879 0 50959 17342 2 1759.8863 880.4512 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 6 2989.3 - 3.04E+06 - - - 567.6064 - 3.898 0.556 - 974.6 1 1 0 0.9984 18 0 0 0 1.21E+05 6.31E+07 - - - 6.1789 0.9997 221125_WJC_METTL3_EV_vs_WT_F04.17343.17343.2 0.000567 20-Dec K.SSFNLGTIETK[136.11].S sp|P49790|NU153_HUMAN 1 1203.6227 1.37 50960 17343 2 1203.620226 602.8186 Nuclear pore complex protein Nup153 OS=Homo sapiens OX=9606 GN=NUP153 PE=1 SV=2 5.72 2989.4 - 1.53E+06 - - - -2.0289 - 2.255 0.484 - 333 1 2 0 -0.0024 11 0 0 0 2.18E+07 1.59E+07 - - - 4.8148 0.9998 221125_WJC_METTL3_EV_vs_WT_F04.17345.17345.2 6.60E-05 24-Sep R.YSSSSIPEPFGSR[166.11].G "sp|Q8WUF5|IASPP_HUMAN,tr|K7EN03|K7EN03_HUMAN" 2 1422.6655 2.83 50962 17345 2 1422.664316 712.34 RelA-associated inhibitor OS=Homo sapiens OX=9606 GN=PPP1R13L PE=1 SV=4 6 2989.7 - 676753 - - - -0.8175 - 1.82 0.486 - 173.2 1 2 0 -0.0012 13 0 0 0 3.83E+07 1.35E+07 - - - 4.1672 0.9999 221125_WJC_METTL3_EV_vs_WT_F04.17349.17349.2 4.30E-07 15/22 K.NVPQVVNVQELK.N "sp|P35658|NU214_HUMAN,tr|A0A0A0MSW3|A0A0A0MSW3_HUMAN,tr|H0YF36|H0YF36_HUMAN,tr|A0A494C1F2|A0A494C1F2_HUMAN" 4 1365.7616 1.92 50964 17349 2 1365.761317 683.8881 Nuclear pore complex protein Nup214 OS=Homo sapiens OX=9606 GN=NUP214 PE=1 SV=2 6 2990.2 - 2.00E+06 - - - -0.2182 - 2.441 0.549 - 660.3 1 2 0 -0.0003 12 0 0 0 2.47E+07 1.29E+07 - - - 5.4439 1 221125_WJC_METTL3_EV_vs_WT_F04.17350.17350.3 4.39E-08 17/64 K.VTHAVVTVPAYFNDAQR[166.11].Q "sp|P11021|BIP_HUMAN,tr|A0A7P0TB36|A0A7P0TB36_HUMAN,tr|A0A7P0TAI0|A0A7P0TAI0_HUMAN" 3 1896.9722 0.38 50965 17350 3 1896.969798 633.3313 Endoplasmic reticulum chaperone BiP OS=Homo sapiens OX=9606 GN=HSPA5 PE=1 SV=2 6.71 2990.3 - 1.17E+06 - - - -1.2483 - 3.401 0.486 - 574.9 1 2 0 -0.0024 17 0 0 0 1.35E+07 3.52E+07 - - - 7.0501 0.9998 221125_WJC_METTL3_EV_vs_WT_F04.17352.17352.2 1.63E-08 13/28 R.ISQSNYIPTQQDVLR[166.11].T sp|P08754|GNAI3_HUMAN 1 1770.914 0.33 50967 17352 2 1770.911764 886.4643 Guanine nucleotide-binding protein G(i) subunit alpha-3 OS=Homo sapiens OX=9606 GN=GNAI3 PE=1 SV=3 5.84 2990.6 - 994015 - - - -1.253 - 2.648 0.465 - 247.8 1 2 0 -0.0022 15 0 0 0 5.80E+06 1.73E+07 - - - 4.8689 0.9999 221125_WJC_METTL3_EV_vs_WT_F04.17353.17353.3 1.12E-07 20/72 R.LVSSPELGHDEFSTQALAR[166.11].Q sp|O15020|SPTN2_HUMAN 1 2066.0308 2.29 50968 17353 3 2066.023716 689.6842 "Spectrin beta chain, non-erythrocytic 2 OS=Homo sapiens OX=9606 GN=SPTBN2 PE=1 SV=3" 4.65 2990.7 - 905173 - - - -3.4302 - 2.987 0.525 - 398.8 1 2 0 -0.0071 19 0 0 0 1.89E+07 8.24E+06 - - - 7.0797 1 221125_WJC_METTL3_EV_vs_WT_F04.17358.17358.3 0.00835 17/56 K.NQTPLPLIK[136.11]PYAGPR[166.11].L sp|Q9HBM6|TAF9B_HUMAN 1 1681.9634 1.27 50971 17358 3 1681.961895 561.6618 Transcription initiation factor TFIID subunit 9B OS=Homo sapiens OX=9606 GN=TAF9B PE=1 SV=1 9.99 2991.4 - 1.76E+06 - - - -0.9221 - 3.093 0.493 - 408.3 1 2 0 -0.0016 15 0 0 0 3.38E+07 2.65E+07 - - - 6.9824 1 221125_WJC_METTL3_EV_vs_WT_F04.17359.17359.3 3.05E-08 14/56 K.FEEHVQSVDIAAFNK.L "sp|P29692|EF1D_HUMAN,tr|E9PQZ1|E9PQZ1_HUMAN,tr|E9PRY8|E9PRY8_HUMAN" 3 1732.842 1.56 50972 17359 3 1732.841435 578.6213 Elongation factor 1-delta OS=Homo sapiens OX=9606 GN=EEF1D PE=1 SV=5 4.65 2991.4 - 1.17E+06 - - - -0.3549 - 2.668 0.519 - 165.4 1 2 0 -0.0006 15 0 0 0 9.85E+06 6.33E+06 - - - 6.8868 0.9565 221125_WJC_METTL3_EV_vs_WT_F04.17360.17360.3 5.10E-05 17/60 L.LTTAEVVVTEIPK[136.11]EEK[136.11].D "sp|P10809|CH60_HUMAN,tr|A0A7I2V2X6|A0A7I2V2X6_HUMAN,tr|A0A7I2YQK6|A0A7I2YQK6_HUMAN" 3 1801.0055 1.33 50973 17360 3 1801.002687 601.3425 "60 kDa heat shock protein, mitochondrial OS=Homo sapiens OX=9606 GN=HSPD1 PE=1 SV=2" 4.49 2991.6 - 1.48E+06 - - - -1.5874 - 2.595 0.411 - 310.6 1 1 1 -0.0029 16 0 0 0 2.49E+07 1.88E+07 - - - 5.5682 1 221125_WJC_METTL3_EV_vs_WT_F04.17361.17361.2 2.52E-08 18/30 K.GPPQSPVFEGVYNNSR.M "sp|Q8WWM7|ATX2L_HUMAN,tr|H3BSK9|H3BSK9_HUMAN,tr|H3BUF6|H3BUF6_HUMAN" 3 1746.8325 2.34 50974 17361 2 1746.834461 874.4236 Ataxin-2-like protein OS=Homo sapiens OX=9606 GN=ATXN2L PE=1 SV=2 6 2991.7 - 893495 - - - 1.0951 - 3.515 0.661 - 871 1 2 0 0.0019 16 0 0 0 1.74E+07 7.44E+06 - - - 7.013 0.9996 221125_WJC_METTL3_EV_vs_WT_F04.17362.17362.2 1.94E-06 13/28 R.TQTPPLGQTPQLGLK.T "sp|P78344|IF4G2_HUMAN,tr|E9PKF8|E9PKF8_HUMAN,tr|H0Y3P2|H0Y3P2_HUMAN,tr|D3DQV9|D3DQV9_HUMAN" 4 1577.8777 2.65 50975 17362 2 1577.873159 789.9461 Eukaryotic translation initiation factor 4 gamma 2 OS=Homo sapiens OX=9606 GN=EIF4G2 PE=1 SV=1 8.41 2991.8 - 797915 - - - -2.8824 - 2.426 0.588 - 352.8 1 2 0 -0.0045 15 0 0 0 1.94E+08 7.31E+07 - - - 5.5614 0.9899 221125_WJC_METTL3_EV_vs_WT_F04.17363.17363.2 0.0108 13/20 K.EIKIEISELNR.V sp|P35908|K22E_HUMAN 1 1342.7456 999 50976 17363 2 1342.742081 672.3801 "Keratin, type II cytoskeletal 2 epidermal OS=Homo sapiens OX=9606 GN=KRT2 PE=1 SV=2" 4.79 2992 - 749868 - - - -2.6431 - 2.455 0.305 - 490.9 1 2 1 -0.0035 11 0 0 0 8.66E+06 0.00E+00 - - - 3.7223 0.9931 221125_WJC_METTL3_EV_vs_WT_F04.17366.17366.3 0.00511 13/56 R.ISQSNYIPTQQDVLR[166.11].T sp|P08754|GNAI3_HUMAN 1 1770.914 3.57 50979 17366 3 1770.904488 591.3119 Guanine nucleotide-binding protein G(i) subunit alpha-3 OS=Homo sapiens OX=9606 GN=GNAI3 PE=1 SV=3 5.84 2992.4 - 584012 - - - -5.3616 - 2.268 0.311 - 166.2 1 2 0 -0.0095 15 0 0 0 1.85E+07 5.18E+06 - - - 4.1415 0.9999 221125_WJC_METTL3_EV_vs_WT_F04.17368.17368.2 9.38E-07 26-Oct K.SLC[160.03]IGATYDVTDSR[166.11].L "sp|O00541|PESC_HUMAN,tr|B3KXD6|B3KXD6_HUMAN,tr|B5MCF9|B5MCF9_HUMAN" 3 1566.7223 0.53 50981 17368 2 1566.720048 784.3684 Pescadillo homolog OS=Homo sapiens OX=9606 GN=PES1 PE=1 SV=1 4.21 2992.6 - 420358 - - - -1.4642 - 2.309 0.583 - 290.6 1 2 0 -0.0023 14 0 0 0 3.57E+06 6.68E+06 - - - 5.4463 0.9998 221125_WJC_METTL3_EV_vs_WT_F04.17373.17373.2 5.49E-06 14/22 K.NVPQVVNVQELK[136.11].N "sp|P35658|NU214_HUMAN,tr|A0A0A0MSW3|A0A0A0MSW3_HUMAN,tr|H0YF36|H0YF36_HUMAN,tr|A0A494C1F2|A0A494C1F2_HUMAN" 4 1373.7758 1.92 50984 17373 2 1373.774695 687.8952 Nuclear pore complex protein Nup214 OS=Homo sapiens OX=9606 GN=NUP214 PE=1 SV=2 6 2993.2 - 812272 - - - -0.8153 - 1.999 0.45 - 563.9 1 2 0 -0.0011 12 0 0 0 2.47E+07 1.29E+07 - - - 4.1868 1 221125_WJC_METTL3_EV_vs_WT_F04.17375.17375.3 5.68E-07 14/48 R.STFKPVIDGSMLK.N "sp|Q8IWC1|MA7D3_HUMAN,tr|A0A0A0MRP0|A0A0A0MRP0_HUMAN" 2 1421.7588 0.93 50986 17375 3 1421.756569 474.9269 MAP7 domain-containing protein 3 OS=Homo sapiens OX=9606 GN=MAP7D3 PE=1 SV=2 8.31 2993.4 - 998910 - - - -1.5952 - 2.68 0.552 - 215.6 1 2 0 -0.0023 13 0 0 0 8.83E+06 9.53E+06 - - - 7.3665 0.9998 221125_WJC_METTL3_EV_vs_WT_F04.17376.17376.2 0.01 28-Dec R.GALQNIIPASTGAAK[136.11].A "sp|P04406|G3P_HUMAN,tr|E7EUT5|E7EUT5_HUMAN" 2 1418.7973 1.07 50987 17376 2 1418.796184 710.4059 Glyceraldehyde-3-phosphate dehydrogenase OS=Homo sapiens OX=9606 GN=GAPDH PE=1 SV=3 8.75 2993.5 - 992270 - - - -0.7711 - 2.721 0.406 - 313.4 1 2 0 -0.0011 15 0 0 0 1.52E+10 1.41E+10 - - - 4.5004 0.9984 221125_WJC_METTL3_EV_vs_WT_F04.17378.17378.3 0.000127 15/44 R.YQILPLHSQIPR[166.11].E sp|Q08211|DHX9_HUMAN 1 1473.8332 1.21 50989 17378 3 1473.829221 492.285 ATP-dependent RNA helicase A OS=Homo sapiens OX=9606 GN=DHX9 PE=1 SV=4 8.75 2993.7 - 681353 - - - -2.6686 - 2.572 0.232 - 280.4 1 2 0 -0.0039 12 0 0 0 1.45E+07 1.20E+07 - - - 3.744 0.9999 221125_WJC_METTL3_EV_vs_WT_F04.17381.17381.3 1.92E-07 17/40 R.NDEELNKLLGR.V "sp|Q93077|H2A1C_HUMAN,sp|P04908|H2A1B_HUMAN,sp|Q7L7L0|H2A3_HUMAN" 3 1299.6783 1.32 50992 17381 3 1299.678289 434.2334 Histone H2A type 1-C OS=Homo sapiens OX=9606 GN=H2AC6 PE=1 SV=3 4.68 2994.1 - 533871 - - - 0.0077 - 2.828 0.546 - 596.6 1 2 1 0 11 0 0 0 6.30E+06 4.77E+06 - - - 7.5806 0.9999 221125_WJC_METTL3_EV_vs_WT_F04.17383.17383.2 1.80E-10 15/30 K.DTLQTVSSSPVTEISR.E sp|Q5T3J3|LRIF1_HUMAN 1 1718.8687 1.97 50994 17383 2 1718.866998 860.4416 Ligand-dependent nuclear receptor-interacting factor 1 OS=Homo sapiens OX=9606 GN=LRIF1 PE=1 SV=1 4.37 2994.4 - 452434 - - - -0.9663 - 3.009 0.417 - 584.4 1 2 0 -0.0017 16 0 0 0 8.96E+06 4.56E+06 - - - 4.8288 0.99 221125_WJC_METTL3_EV_vs_WT_F04.17384.17384.3 0.261 28-May K.FHNWFDDR[166.11].A "sp|P46977|STT3A_HUMAN,tr|A0A0C4DH80|A0A0C4DH80_HUMAN,tr|E9PN73|E9PN73_HUMAN,tr|E9PI32|E9PI32_HUMAN" 4 1145.4918 0.03 50995 17384 3 1145.489538 382.8379 Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit STT3A OS=Homo sapiens OX=9606 GN=STT3A PE=1 SV=2 5.21 2994.5 - 359700 - - - -1.9852 - 1.296 0.252 - 53.6 1 2 0 -0.0023 8 0 0 0 1.05E+05 3.68E+06 - - - 2.1593 1 221125_WJC_METTL3_EV_vs_WT_F04.17385.17385.2 3.16E-09 14/34 R.QMASQAPAVNTLTESTLK[136.11].N "sp|P35658|NU214_HUMAN,tr|A0A0A0MSW3|A0A0A0MSW3_HUMAN,tr|H0YF36|H0YF36_HUMAN,tr|A0A494C1F2|A0A494C1F2_HUMAN" 4 1896.9706 1.9 50996 17385 2 1896.962407 949.4926 Nuclear pore complex protein Nup214 OS=Homo sapiens OX=9606 GN=NUP214 PE=1 SV=2 6 2994.6 - 263200 - - - -4.3338 - 3.13 0.638 - 387.5 1 2 0 -0.0082 18 0 0 0 6.48E+06 3.41E+06 - - - 6.556 0.9962 221125_WJC_METTL3_EV_vs_WT_F04.17386.17386.3 0.0696 Jul-40 K.DSTGHVGFIFK.N "sp|O00560|SDCB1_HUMAN,tr|E9PBU7|E9PBU7_HUMAN,tr|B4DHN5|B4DHN5_HUMAN,tr|G5EA09|G5EA09_HUMAN" 4 1206.6033 1.34 50997 17386 3 1206.60218 403.2084 Syntenin-1 OS=Homo sapiens OX=9606 GN=SDCBP PE=1 SV=1 6.74 2994.8 - 262791 - - - -0.9473 - 1.497 0.264 - 42.2 3 2 0 -0.0011 11 0 0 0 4.55E+06 3.40E+06 - - - 2.4084 0.9991 221125_WJC_METTL3_EV_vs_WT_F04.17393.17393.3 0.00626 Oct-72 K.NLPPSGAVPVTGIPPHVVK.V "sp|Q13283|G3BP1_HUMAN,tr|A0A7I2V5M7|A0A7I2V5M7_HUMAN,tr|A0A7I2YQM1|A0A7I2YQM1_HUMAN,tr|A0A7P0P2U7|A0A7P0P2U7_HUMAN,tr|A0A7I2YQU8|A0A7I2YQU8_HUMAN,tr|A0A7I2V548|A0A7I2V548_HUMAN,tr|A0A7I2V651|A0A7I2V651_HUMAN,tr|A0A7I2V4D8|A0A7I2V4D8_HUMAN,tr|A0A7I2YQN9|A0A7I2YQN9_HUMAN" 9 1878.0727 1.35 51002 17393 3 1878.076472 627.0315 Ras GTPase-activating protein-binding protein 1 OS=Homo sapiens OX=9606 GN=G3BP1 PE=1 SV=1 8.76 2995.5 - 2.03E+06 - - - 1.9989 - 1.934 0.332 - 69.3 1 2 0 0.0038 19 0 0 0 1.05E+08 7.77E+07 - - - 3.8609 0.9998 221125_WJC_METTL3_EV_vs_WT_F04.17394.17394.2 5.56E-06 16/28 R.GALQNIIPASTGAAK.A "sp|P04406|G3P_HUMAN,tr|E7EUT5|E7EUT5_HUMAN" 2 1410.7831 1.07 51003 17394 2 1410.785043 706.3988 Glyceraldehyde-3-phosphate dehydrogenase OS=Homo sapiens OX=9606 GN=GAPDH PE=1 SV=3 8.75 2995.6 - 1.61E+06 - - - 1.3928 - 2.427 0.553 - 606 1 2 0 0.002 15 0 0 0 1.52E+10 1.41E+10 - - - 5.3047 0.9997 221125_WJC_METTL3_EV_vs_WT_F04.17395.17395.3 5.71E-05 Sep-52 R.AIESMEQQLSELK[136.11]K[136.11].T sp|P12270|TPR_HUMAN 1 1648.8677 2.33 51004 17395 3 1648.869299 550.6298 Nucleoprotein TPR OS=Homo sapiens OX=9606 GN=TPR PE=1 SV=3 4.79 2995.7 - 1.52E+06 - - - 0.9861 - 1.759 0.39 - 60.7 1 2 0 0.0016 14 0 0 0 1.85E+07 7.93E+06 - - - 4.3885 1 221125_WJC_METTL3_EV_vs_WT_F04.17396.17396.3 1.36E-05 14/48 R.STFK[136.11]PVIDGSMLK[136.11].N "sp|Q8IWC1|MA7D3_HUMAN,tr|A0A0A0MRP0|A0A0A0MRP0_HUMAN" 2 1437.7872 0.93 51005 17396 3 1437.789672 480.2697 MAP7 domain-containing protein 3 OS=Homo sapiens OX=9606 GN=MAP7D3 PE=1 SV=2 8.31 2995.7 - 1.37E+06 - - - 1.6936 - 2.66 0.551 - 238.7 1 2 0 0.0024 13 0 0 0 8.83E+06 9.53E+06 - - - 7.335 0.9999 221125_WJC_METTL3_EV_vs_WT_F04.17398.17398.2 3.06E-06 16/26 K.STPVTSAVQIPEVK[136.11].Q sp|Q96KR1|ZFR_HUMAN 1 1462.8123 1.23 51007 17398 2 1462.812964 732.4134 Zinc finger RNA-binding protein OS=Homo sapiens OX=9606 GN=ZFR PE=1 SV=2 5.72 2995.9 - 1.19E+06 - - - 0.4813 - 2.587 0.578 - 757.8 1 2 0 0.0007 14 0 0 0 4.06E+07 3.31E+07 - - - 5.6951 0.9998 221125_WJC_METTL3_EV_vs_WT_F04.17399.17399.2 2.67E-06 13/28 R.TQTPPLGQTPQLGLK[136.11].T "sp|P78344|IF4G2_HUMAN,tr|E9PKF8|E9PKF8_HUMAN,tr|H0Y3P2|H0Y3P2_HUMAN,tr|D3DQV9|D3DQV9_HUMAN" 4 1585.8919 2.64 51008 17399 2 1585.893078 793.9532 Eukaryotic translation initiation factor 4 gamma 2 OS=Homo sapiens OX=9606 GN=EIF4G2 PE=1 SV=1 8.41 2996 - 1.15E+06 - - - 0.7384 - 2.117 0.484 - 360.9 1 2 0 0.0012 15 0 0 0 1.93E+08 7.31E+07 - - - 4.4594 1 221125_WJC_METTL3_EV_vs_WT_F04.17400.17400.3 1.96E-08 18/60 K.GPPQSPVFEGVYNNSR.M "sp|Q8WWM7|ATX2L_HUMAN,tr|H3BSK9|H3BSK9_HUMAN,tr|H3BUF6|H3BUF6_HUMAN" 3 1746.8325 2.16 51009 17400 3 1746.836967 583.2848 Ataxin-2-like protein OS=Homo sapiens OX=9606 GN=ATXN2L PE=1 SV=2 6 2996.1 - 1.11E+06 - - - 2.5297 - 3.314 0.575 - 381.9 1 2 0 0.0044 16 0 0 0 1.43E+07 6.64E+06 - - - 8.0238 0.9999 221125_WJC_METTL3_EV_vs_WT_F04.17402.17402.3 1.75E-05 14/40 R.NDEELNK[136.11]LLGR[166.11].V "sp|Q93077|H2A1C_HUMAN,sp|P04908|H2A1B_HUMAN,sp|Q7L7L0|H2A3_HUMAN" 3 1317.7007 1.32 51011 17402 3 1317.700906 440.2409 Histone H2A type 1-C OS=Homo sapiens OX=9606 GN=H2AC6 PE=1 SV=3 4.68 2996.4 - 934799 - - - 0.1191 - 2.398 0.538 - 406.5 1 2 1 0.0002 11 0 0 0 6.30E+06 4.77E+06 - - - 7.0228 0.9997 221125_WJC_METTL3_EV_vs_WT_F04.17403.17403.3 1.59E-06 17/52 K.VLALLDVPDKSQEK.A sp|Q9NX62|IMPA3_HUMAN 1 1553.8665 1.22 51012 17403 3 1553.863155 518.9628 "Golgi-resident adenosine 3',5'-bisphosphate 3'-phosphatase OS=Homo sapiens OX=9606 GN=BPNT2 PE=1 SV=1" 4.56 2996.5 - 889340 - - - -2.136 - 3.095 0.43 - 333.1 1 2 1 -0.0033 14 0 0 0 3.70E+07 3.03E+07 - - - 6.3356 1 221125_WJC_METTL3_EV_vs_WT_F04.17404.17404.2 5.09E-10 15/26 R.TSESLC[160.03]QNNMVILK[136.11].L "sp|O14980|XPO1_HUMAN,tr|A0A7I2V461|A0A7I2V461_HUMAN,tr|A0A7I2V3N0|A0A7I2V3N0_HUMAN,tr|A0A7I2V4A3|A0A7I2V4A3_HUMAN,tr|C9JKM9|C9JKM9_HUMAN,tr|A0A7I2V3W6|A0A7I2V3W6_HUMAN,tr|A0A7I2YQV4|A0A7I2YQV4_HUMAN,tr|A0A7I2YQX3|A0A7I2YQX3_HUMAN,tr|A0A7I2V2Y6|A0A7I2V2Y6_HUMAN,tr|A0A7I2V6B9|A0A7I2V6B9_HUMAN,tr|A0A7I2V3P3|A0A7I2V3P3_HUMAN,tr|A0A7I2V2S3|A0A7I2V2S3_HUMAN" 12 1643.8102 0.49 51013 17404 2 1643.811385 822.9124 Exportin-1 OS=Homo sapiens OX=9606 GN=XPO1 PE=1 SV=1 5.66 2996.6 - 843444 - - - 0.7039 - 3.355 0.626 - 1061.2 1 2 0 0.0012 14 0 0 0 4.68E+06 9.47E+06 - - - 6.7018 0.9999 221125_WJC_METTL3_EV_vs_WT_F04.17407.17407.3 0.00423 17/52 K.VLALLDVPDK[136.11]SQEK[136.11].A sp|Q9NX62|IMPA3_HUMAN 1 1569.8949 1.22 51016 17407 3 1569.896402 524.3056 "Golgi-resident adenosine 3',5'-bisphosphate 3'-phosphatase OS=Homo sapiens OX=9606 GN=BPNT2 PE=1 SV=1" 4.56 2997 - 655547 - - - 0.9733 - 3.497 0.476 - 391.4 1 2 1 0.0015 14 0 0 0 3.70E+07 3.03E+07 - - - 7.1735 1 221125_WJC_METTL3_EV_vs_WT_F04.17408.17408.2 3.36E-06 26-Dec R.TSESLC[160.03]QNNMVILK.L "sp|O14980|XPO1_HUMAN,tr|A0A7I2V461|A0A7I2V461_HUMAN,tr|A0A7I2V3N0|A0A7I2V3N0_HUMAN,tr|A0A7I2V4A3|A0A7I2V4A3_HUMAN,tr|C9JKM9|C9JKM9_HUMAN,tr|A0A7I2V3W6|A0A7I2V3W6_HUMAN,tr|A0A7I2YQV4|A0A7I2YQV4_HUMAN,tr|A0A7I2YQX3|A0A7I2YQX3_HUMAN,tr|A0A7I2V2Y6|A0A7I2V2Y6_HUMAN,tr|A0A7I2V6B9|A0A7I2V6B9_HUMAN,tr|A0A7I2V3P3|A0A7I2V3P3_HUMAN,tr|A0A7I2V2S3|A0A7I2V2S3_HUMAN" 12 1635.796 0.49 51017 17408 2 1635.796361 818.9053 Exportin-1 OS=Homo sapiens OX=9606 GN=XPO1 PE=1 SV=1 5.66 2997.1 - 626517 - - - 0.2036 - 2.957 0.544 - 596.4 1 2 0 0.0003 14 0 0 0 4.68E+06 9.47E+06 - - - 5.7796 0.9984 221125_WJC_METTL3_EV_vs_WT_F04.17409.17409.2 0.000175 22-Dec K.QIQDQLNELEER[166.11].A "sp|Q92541|RTF1_HUMAN,tr|H0YKX1|H0YKX1_HUMAN" 2 1523.7455 0.03 51018 17409 2 1523.739041 762.88 RNA polymerase-associated protein RTF1 homolog OS=Homo sapiens OX=9606 GN=RTF1 PE=1 SV=4 4 2997.2 - 540940 - - - -4.252 - 2.445 0.431 - 621 1 2 0 -0.0065 12 0 0 0 1.50E+05 4.56E+06 - - - 4.5747 1 221125_WJC_METTL3_EV_vs_WT_F04.17412.17412.2 8.97E-11 16/28 K.NQVALNPQNTVFDAK[136.11].R "sp|P0DMV8|HS71A_HUMAN,sp|P0DMV9|HS71B_HUMAN,tr|A0A0G2JIW1|A0A0G2JIW1_HUMAN" 3 1665.8566 0.16 51020 17412 2 1665.856564 833.9356 Heat shock 70 kDa protein 1A OS=Homo sapiens OX=9606 GN=HSPA1A PE=1 SV=1 5.84 2997.6 - 3.02E+06 - - - -0.012 - 3.146 0.673 - 666.1 1 2 0 0 15 0 0 0 2.21E+09 1.41E+10 - - - 6.8296 0.9998 221125_WJC_METTL3_EV_vs_WT_F04.17414.17414.3 1.02E-05 Nov-52 R.AIESMEQQLSELKK.T sp|P12270|TPR_HUMAN 1 1632.8393 2.33 51022 17414 3 1632.843104 545.287 Nucleoprotein TPR OS=Homo sapiens OX=9606 GN=TPR PE=1 SV=3 4.79 2997.8 - 3.35E+06 - - - 2.3462 - 2.277 0.415 - 114 1 2 0 0.0038 14 0 0 0 1.85E+07 7.93E+06 - - - 5.3526 1 221125_WJC_METTL3_EV_vs_WT_F04.17415.17415.3 3.80E-08 17/56 R.TQTPPLGQTPQLGLK.T "sp|P78344|IF4G2_HUMAN,tr|E9PKF8|E9PKF8_HUMAN,tr|H0Y3P2|H0Y3P2_HUMAN,tr|D3DQV9|D3DQV9_HUMAN" 4 1577.8777 3.02 51023 17415 3 1577.881125 526.9665 Eukaryotic translation initiation factor 4 gamma 2 OS=Homo sapiens OX=9606 GN=EIF4G2 PE=1 SV=1 8.41 2997.8 - 2.58E+06 - - - 2.1662 - 3.017 0.54 - 386.9 1 2 0 0.0034 15 0 0 0 8.51E+07 2.82E+07 - - - 7.4409 0.9999 221125_WJC_METTL3_EV_vs_WT_F04.17417.17417.3 2.03E-07 16/52 K.SGEEGMPDLAHVMR.L "sp|O75688|PPM1B_HUMAN,tr|B8ZZF0|B8ZZF0_HUMAN,tr|A0A3B3IS24|A0A3B3IS24_HUMAN,tr|C9JIR6|C9JIR6_HUMAN" 4 1527.681 3.52 51025 17417 3 1527.684636 510.2343 Protein phosphatase 1B OS=Homo sapiens OX=9606 GN=PPM1B PE=1 SV=1 4.65 2998 - 1.20E+06 - - - 2.3814 - 2.954 0.499 - 495.1 1 2 0 0.0036 14 0 0 0 1.04E+09 2.95E+08 - - - 6.9809 0.9994 221125_WJC_METTL3_EV_vs_WT_F04.17418.17418.3 0.000548 Dec-44 K.LR[166.11]LDSIVIQQGR[166.11].L "sp|O60264|SMCA5_HUMAN,sp|P28370|SMCA1_HUMAN,tr|A0A0A0MRP6|A0A0A0MRP6_HUMAN,tr|B7ZLQ5|B7ZLQ5_HUMAN" 4 1416.8316 0.73 51026 17418 3 1416.834159 473.2845 SWI\SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A member 5 OS=Homo sapiens OX=9606 GN=SMARCA5 PE=1 SV=1 9.6 2998.1 - 1.16E+06 - - - 1.8153 - 2.714 0.38 - 348.7 1 2 1 0.0026 12 0 0 0 7.23E+06 9.86E+06 - - - 5.5434 1 221125_WJC_METTL3_EV_vs_WT_F04.17419.17419.2 2.46E-17 21/34 R.QMASQAPAVNTLTESTLK.N "sp|P35658|NU214_HUMAN,tr|A0A0A0MSW3|A0A0A0MSW3_HUMAN,tr|H0YF36|H0YF36_HUMAN,tr|A0A494C1F2|A0A494C1F2_HUMAN" 4 1888.9564 1.9 51027 17419 2 1888.958467 945.4855 Nuclear pore complex protein Nup214 OS=Homo sapiens OX=9606 GN=NUP214 PE=1 SV=2 6 2998.2 - 1.11E+06 - - - 1.0794 - 3.754 0.724 - 1063.4 1 2 0 0.002 18 0 0 0 6.48E+06 3.41E+06 - - - 7.64 1 221125_WJC_METTL3_EV_vs_WT_F04.17420.17420.3 6.12E-09 17/52 K.GFFDPNTHENLTYR.Q "sp|Q15149|PLEC_HUMAN,tr|H0YDN1|H0YDN1_HUMAN" 2 1709.7798 1.33 51028 17420 3 1709.78297 570.9339 Plectin OS=Homo sapiens OX=9606 GN=PLEC PE=1 SV=3 5.32 2998.3 - 1.06E+06 - - - 1.8634 - 2.992 0.606 - 259.7 1 2 0 0.0032 14 0 0 0 1.47E+07 1.10E+07 - - - 8.2079 0.9999 221125_WJC_METTL3_EV_vs_WT_F04.17421.17421.3 3.84E-05 18/56 R.TQTPPLGQTPQLGLK[136.11].T "sp|P78344|IF4G2_HUMAN,tr|E9PKF8|E9PKF8_HUMAN,tr|H0Y3P2|H0Y3P2_HUMAN,tr|D3DQV9|D3DQV9_HUMAN" 4 1585.8919 3.01 51029 17421 3 1585.894904 529.6379 Eukaryotic translation initiation factor 4 gamma 2 OS=Homo sapiens OX=9606 GN=EIF4G2 PE=1 SV=1 8.41 2998.3 - 1.05E+06 - - - 1.8898 - 2.927 0.464 - 475.2 1 2 0 0.003 15 0 0 0 8.49E+07 2.82E+07 - - - 6.5147 0.9998 221125_WJC_METTL3_EV_vs_WT_F04.17422.17422.4 2.64E-06 21/90 K.AIGIEPSLATYHHIIR[166.11].L sp|Q96EY7|PTCD3_HUMAN 1 1799.9922 1.34 51030 17422 4 1799.99518 451.0053 "Pentatricopeptide repeat domain-containing protein 3, mitochondrial OS=Homo sapiens OX=9606 GN=PTCD3 PE=1 SV=3" 6.96 2998.5 - 841087 - - - 1.6706 - 3.63 0.392 - 415.5 1 2 0 0.003 16 0 0 0 6.64E+06 4.96E+06 - - - 3.0913 0.9998 221125_WJC_METTL3_EV_vs_WT_F04.17423.17423.3 1.90E-05 16/56 K.NQTPLPLIKPYAGPR.L sp|Q9HBM6|TAF9B_HUMAN 1 1663.941 1.27 51031 17423 3 1663.944829 555.6543 Transcription initiation factor TFIID subunit 9B OS=Homo sapiens OX=9606 GN=TAF9B PE=1 SV=1 9.99 2998.6 - 823370 - - - 2.3156 - 2.438 0.399 - 270.6 1 2 0 0.0039 15 0 0 0 3.38E+07 2.65E+07 - - - 5.3128 0.9997 221125_WJC_METTL3_EV_vs_WT_F04.17424.17424.3 0.00206 13/44 K.LRLDSIVIQQGR.L "sp|O60264|SMCA5_HUMAN,sp|P28370|SMCA1_HUMAN,tr|A0A0A0MRP6|A0A0A0MRP6_HUMAN,tr|B7ZLQ5|B7ZLQ5_HUMAN" 4 1396.815 0.73 51032 17424 3 1396.817142 466.6123 SWI\SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A member 5 OS=Homo sapiens OX=9606 GN=SMARCA5 PE=1 SV=1 9.6 2998.7 - 795898 - - - 1.4998 - 2.437 0.461 - 352.7 1 2 1 0.0021 12 0 0 0 7.23E+06 9.86E+06 - - - 6.1482 1 221125_WJC_METTL3_EV_vs_WT_F04.17425.17425.3 4.89E-06 Nov-40 K.DSTGHVGFIFK[136.11].N "sp|O00560|SDCB1_HUMAN,tr|E9PBU7|E9PBU7_HUMAN,tr|B4DHN5|B4DHN5_HUMAN,tr|G5EA09|G5EA09_HUMAN" 4 1214.6175 1.34 51033 17425 3 1214.618607 405.8798 Syntenin-1 OS=Homo sapiens OX=9606 GN=SDCBP PE=1 SV=1 6.74 2998.8 - 636190 - - - 0.8925 - 2.331 0.506 - 179.7 1 2 0 0.0011 11 0 0 0 4.55E+06 3.40E+06 - - - 6.5853 1 221125_WJC_METTL3_EV_vs_WT_F04.17426.17426.3 1.43E-07 17/52 K.QEAEGLALDSPWHR[166.11].F "sp|Q8N0Y2|ZN444_HUMAN,tr|K7EK55|K7EK55_HUMAN,tr|K7ELZ3|K7ELZ3_HUMAN,tr|K7EMV5|K7EMV5_HUMAN,tr|K7EJH4|K7EJH4_HUMAN,tr|K7ESL2|K7ESL2_HUMAN,tr|K7EJ91|K7EJ91_HUMAN" 7 1617.7775 1.03 51034 17426 3 1617.780594 540.2664 Zinc finger protein 444 OS=Homo sapiens OX=9606 GN=ZNF444 PE=1 SV=1 4.65 2998.9 - 537353 - - - 1.9193 - 3.066 0.5 - 601.3 1 2 0 0.0031 14 0 0 0 5.70E+06 5.52E+06 - - - 7.0911 1 221125_WJC_METTL3_EV_vs_WT_F04.17428.17428.3 2.27E-11 17/52 K.SGEEGMPDLAHVMR[166.11].L "sp|O75688|PPM1B_HUMAN,tr|B8ZZF0|B8ZZF0_HUMAN,tr|A0A3B3IS24|A0A3B3IS24_HUMAN,tr|C9JIR6|C9JIR6_HUMAN" 4 1537.6893 3.53 51036 17428 3 1537.692591 513.5704 Protein phosphatase 1B OS=Homo sapiens OX=9606 GN=PPM1B PE=1 SV=1 4.65 2999.1 - 439377 - - - 2.161 - 3.277 0.646 - 605.7 1 2 0 0.0033 14 0 0 0 1.04E+09 2.95E+08 - - - 8.8956 0.9868 221125_WJC_METTL3_EV_vs_WT_F04.17430.17430.2 1.54E-05 26-Oct T.IENAQPILQIDNAR.L sp|P08779|K1C16_HUMAN 1 1593.8475 999 51038 17430 2 1593.848752 797.931 "Keratin, type I cytoskeletal 16 OS=Homo sapiens OX=9606 GN=KRT16 PE=1 SV=4" 4.37 2999.4 - 378643 - - - 0.8043 - 2.148 0.439 - 214.3 1 1 0 0.0013 14 0 0 0 1.60E+06 0.00E+00 - - - 4.2016 0.9918 221125_WJC_METTL3_EV_vs_WT_F04.17434.17434.3 0.105 Sep-72 R.EVIAEEEPPTVTEPLPENR.E sp|Q02952|AKA12_HUMAN 1 2148.0586 0.42 51041 17434 3 2148.068205 717.0268 A-kinase anchor protein 12 OS=Homo sapiens OX=9606 GN=AKAP12 PE=1 SV=4 3.9 2999.9 - 143712 - - - 4.451 - 2.246 0.269 - 68.5 1 2 0 0.0096 19 0 0 0 6.41E+05 1.52E+06 - - - 3.5244 1 221125_WJC_METTL3_EV_vs_WT_F04.17435.17435.3 3.83E-08 18/48 K.AGQVFLEELGNHK[136.11].A sp|P09543|CN37_HUMAN 1 1448.7503 1.23 51042 17435 3 1448.752062 483.9241 "2',3'-cyclic-nucleotide 3'-phosphodiesterase OS=Homo sapiens OX=9606 GN=CNP PE=1 SV=2" 5.4 2999.9 - 1.96E+06 - - - 1.1969 - 3.103 0.521 - 551.4 1 2 0 0.0017 13 0 0 0 2.55E+07 2.06E+07 - - - 7.4183 1 221125_WJC_METTL3_EV_vs_WT_F04.17436.17436.3 3.10E-10 19/56 K.MYSTDDGVQFHAFGR.V sp|Q15029|U5S1_HUMAN 1 1729.7519 1.59 51043 17436 3 1729.754833 577.5912 116 kDa U5 small nuclear ribonucleoprotein component OS=Homo sapiens OX=9606 GN=EFTUD2 PE=1 SV=1 5.19 3000 - 1.23E+06 - - - 1.7216 - 3.116 0.716 - 419.6 1 2 0 0.003 15 0 0 0 5.10E+07 3.21E+07 - - - 9.4875 1 221125_WJC_METTL3_EV_vs_WT_F04.17437.17437.4 1.24E-06 19/90 K.AIGIEPSLATYHHIIR.L sp|Q96EY7|PTCD3_HUMAN 1 1789.9839 1.3 51044 17437 4 1789.985964 448.5033 "Pentatricopeptide repeat domain-containing protein 3, mitochondrial OS=Homo sapiens OX=9606 GN=PTCD3 PE=1 SV=3" 6.96 3000.1 - 1.22E+06 - - - 1.1514 - 3.654 0.553 - 318 1 2 0 0.0021 16 0 0 0 6.43E+06 4.96E+06 - - - 4.4952 0.9997 221125_WJC_METTL3_EV_vs_WT_F04.17438.17438.3 0.000492 13/52 K.NPEVGLKPVWYSPK.V "sp|P07814|SYEP_HUMAN,tr|V9GYZ6|V9GYZ6_HUMAN" 2 1612.8613 0.83 51045 17438 3 1612.864887 538.6277 Bifunctional glutamate\proline--tRNA ligase OS=Homo sapiens OX=9606 GN=EPRS1 PE=1 SV=5 8.5 3000.2 - 1.11E+06 - - - 2.206 - 2.475 0.355 - 142.9 1 2 0 0.0036 14 0 0 0 3.78E+07 4.58E+07 - - - 4.9053 1 221125_WJC_METTL3_EV_vs_WT_F04.17440.17440.3 0.000267 19/64 R.AALEEVYPDLTPEETR[166.11]R[166.11].N sp|Q9H0D6|XRN2_HUMAN 1 2008.0016 1.05 51047 17440 3 2008.003259 670.3412 5'-3' exoribonuclease 2 OS=Homo sapiens OX=9606 GN=XRN2 PE=1 SV=1 4.25 3000.4 - 954493 - - - 0.8137 - 3.143 0.415 - 414.4 1 2 0 0.0016 17 0 0 0 3.71E+08 3.54E+08 - - - 6.0595 1 221125_WJC_METTL3_EV_vs_WT_F04.17442.17442.2 1.03E-05 15/28 R.NYILDQTNVYGSAQR.R "sp|Q9BUJ2|HNRL1_HUMAN,tr|A0A0A0MRA5|A0A0A0MRA5_HUMAN,tr|M0R3F1|M0R3F1_HUMAN,tr|B7Z4B8|B7Z4B8_HUMAN" 4 1740.8431 1.6 51049 17442 2 1740.845427 871.4288 Heterogeneous nuclear ribonucleoprotein U-like protein 1 OS=Homo sapiens OX=9606 GN=HNRNPUL1 PE=1 SV=2 5.83 3000.6 - 667518 - - - 1.3298 - 2.781 0.603 - 640 1 2 0 0.0023 15 0 0 0 9.19E+07 5.73E+07 - - - 6.0087 1 221125_WJC_METTL3_EV_vs_WT_F04.17443.17443.3 3.35E-07 14/40 K.HMDLC[160.03]LTVVDR.A sp|Q10471|GALT2_HUMAN 1 1357.6482 0.81 51050 17443 3 1357.649573 453.5567 Polypeptide N-acetylgalactosaminyltransferase 2 OS=Homo sapiens OX=9606 GN=GALNT2 PE=1 SV=1 5.21 3000.7 - 652647 - - - 0.9811 - 2.602 0.556 - 313.5 1 2 0 0.0013 11 0 0 0 4.91E+06 6.09E+06 - - - 7.4551 0.9994 221125_WJC_METTL3_EV_vs_WT_F04.17444.17444.3 0.0015 13/44 R.NGTLPWLRPDSK.T sp|P31153|METK2_HUMAN 1 1382.7306 1.14 51051 17444 3 1382.731316 461.9175 S-adenosylmethionine synthase isoform type-2 OS=Homo sapiens OX=9606 GN=MAT2A PE=1 SV=1 8.75 3000.8 - 628399 - - - 0.4824 - 2.233 0.258 - 289.5 1 2 0 0.0007 12 0 0 0 1.41E+07 1.23E+07 - - - 3.643 0.9948 221125_WJC_METTL3_EV_vs_WT_F04.17445.17445.3 0.0628 Oct-60 R.IENLELMSQHGC[160.03]NAWK.V sp|O75934|SPF27_HUMAN 1 1928.8873 1.4 51052 17445 3 1928.890073 643.9697 Pre-mRNA-splicing factor SPF27 OS=Homo sapiens OX=9606 GN=BCAS2 PE=1 SV=1 5.4 3000.9 - 608309 - - - 1.4361 - 1.664 0.23 - 96.5 1 2 0 0.0028 16 0 0 0 1.09E+07 7.82E+06 - - - 2.4101 0.9988 221125_WJC_METTL3_EV_vs_WT_F04.17446.17446.3 3.67E-05 Nov-64 K.FFDANYDGKDYDPVAAR.Q sp|Q15691|MARE1_HUMAN 1 1962.8748 0.16 51053 17446 3 1962.87852 655.2989 Microtubule-associated protein RP\EB family member 1 OS=Homo sapiens OX=9606 GN=MAPRE1 PE=1 SV=3 4.14 3001.1 - 508748 - - - 1.8916 - 2.091 0.397 - 60.8 1 2 1 0.0037 17 0 0 0 4.77E+06 2.90E+07 - - - 4.8286 1 221125_WJC_METTL3_EV_vs_WT_F04.17447.17447.3 1.61E-09 15/72 K.IVDR[166.11]IDNDGDGFVTTEELK[136.11].T sp|Q15293|RCN1_HUMAN 1 2153.0607 1.28 51054 17447 3 2153.061066 718.6942 Reticulocalbin-1 OS=Homo sapiens OX=9606 GN=RCN1 PE=1 SV=1 3.96 3001.2 - 363378 - - - 0.164 - 3.367 0.652 - 254.6 1 2 1 0.0004 19 0 0 0 3.64E+06 2.86E+06 - - - 8.7917 1 221125_WJC_METTL3_EV_vs_WT_F04.17456.17456.3 4.25E-07 13/52 K.NPEVGLK[136.11]PVWYSPK[136.11].V "sp|P07814|SYEP_HUMAN,tr|V9GYZ6|V9GYZ6_HUMAN" 2 1628.8897 0.79 51061 17456 3 1628.891943 543.9705 Bifunctional glutamate\proline--tRNA ligase OS=Homo sapiens OX=9606 GN=EPRS1 PE=1 SV=5 8.5 3002.4 - 2.85E+06 - - - 1.3592 - 2.589 0.476 - 199.9 1 2 0 0.0022 14 0 0 0 3.83E+07 4.83E+07 - - - 6.3744 0.9996 221125_WJC_METTL3_EV_vs_WT_F04.17458.17458.2 0.000179 22-Nov R.DIKPDNLLLDSK.G sp|Q15208|STK38_HUMAN 1 1369.7453 4.21 51063 17458 2 1369.747346 685.8799 Serine\threonine-protein kinase 38 OS=Homo sapiens OX=9606 GN=STK38 PE=1 SV=1 4.43 3002.6 - 1.55E+06 - - - 1.4966 - 2.034 0.411 - 171.2 1 2 0 0.0021 12 0 0 0 3.42E+08 8.11E+07 - - - 3.9441 0.9994 221125_WJC_METTL3_EV_vs_WT_F04.17459.17459.2 3.19E-05 16-Jul R.EYQDLLNVK[136.11].M "sp|P08670|VIME_HUMAN,sp|P14136|GFAP_HUMAN,sp|P17661|DESM_HUMAN,sp|Q16352|AINX_HUMAN,sp|P07197|NFM_HUMAN,sp|P12036|NFH_HUMAN,sp|P07196|NFL_HUMAN,tr|A0A1W2PR46|A0A1W2PR46_HUMAN,tr|A0A1X7SBR3|A0A1X7SBR3_HUMAN,tr|K7EJU1|K7EJU1_HUMAN,tr|A0A1X7SCE1|A0A1X7SCE1_HUMAN,tr|A0A1W2PRT3|A0A1W2PRT3_HUMAN,tr|B0YJC5|B0YJC5_HUMAN,tr|B0YJC4|B0YJC4_HUMAN,tr|E7ESP9|E7ESP9_HUMAN,tr|E7EMV2|E7EMV2_HUMAN" 16 1128.5906 1.88 51064 17459 2 1128.592975 565.3026 Vimentin OS=Homo sapiens OX=9606 GN=VIM PE=1 SV=4 4.37 3002.6 - 1.17E+06 - - - 2.069 - 1.507 0.499 - 218 1 2 0 0.0023 9 0 0 0 2.95E+07 1.57E+07 - - - 3.9124 0.9999 221125_WJC_METTL3_EV_vs_WT_F04.17460.17460.3 2.86E-07 Nov-60 K.WGTLTDC[160.03]VVMR[166.11]DPQTK[136.11].R "sp|P51991|ROA3_HUMAN,tr|A0A7I2V5D8|A0A7I2V5D8_HUMAN,tr|A0A7I2V2R3|A0A7I2V2R3_HUMAN,tr|A0A7I2V4J6|A0A7I2V4J6_HUMAN,tr|A0A7I2V4G0|A0A7I2V4G0_HUMAN,tr|A0A7I2V402|A0A7I2V402_HUMAN" 6 1923.9302 12.46 51065 17460 3 1923.93156 642.3173 Heterogeneous nuclear ribonucleoprotein A3 OS=Homo sapiens OX=9606 GN=HNRNPA3 PE=1 SV=2 5.95 3002.7 - 1.13E+06 - - - 0.7204 - 2.422 0.518 - 106.9 1 2 1 0.0014 16 0 0 0 4.07E+08 3.27E+07 - - - 6.5846 0.9999 221125_WJC_METTL3_EV_vs_WT_F04.17461.17461.2 9.77E-05 13/24 R.FSGSGSGTDFTLK.L "sp|A2NJV5|KV229_HUMAN,sp|A0A087WW87|KV240_HUMAN,sp|P06310|KV230_HUMAN,sp|A0A075B6S2|KVD29_HUMAN,sp|P01614|KVD40_HUMAN,sp|P01615|KVD28_HUMAN,sp|A0A075B6S6|KVD30_HUMAN,sp|A0A075B6P5|KV228_HUMAN,sp|A0A0A0MRZ7|KVD26_HUMAN" 9 1302.6092 999 51066 17461 2 1302.610656 652.3119 Immunoglobulin kappa variable 2-29 OS=Homo sapiens OX=9606 GN=IGKV2-29 PE=3 SV=2 5.84 3002.9 - 1.02E+06 - - - 1.1208 - 2.485 0.524 - 346 1 2 0 0.0015 13 0 0 0 3.02E+07 0.00E+00 - - - 5.247 0.9998 221125_WJC_METTL3_EV_vs_WT_F04.17462.17462.3 2.42E-08 15/56 K.YLDEDTIYHLQPSGR.F sp|P31153|METK2_HUMAN 1 1805.8584 1.28 51067 17462 3 1805.867324 602.9601 S-adenosylmethionine synthase isoform type-2 OS=Homo sapiens OX=9606 GN=MAT2A PE=1 SV=1 4.54 3002.9 - 971484 - - - 4.9262 - 2.521 0.646 - 191.5 1 2 0 0.0089 15 0 0 0 9.25E+07 7.21E+07 - - - 8.1526 1 221125_WJC_METTL3_EV_vs_WT_F04.17463.17463.3 1.84E-05 21/56 K.K[136.11]EDIYAVEIVGGATR[166.11].L "sp|P34932|HSP74_HUMAN,tr|A0A087WTS8|A0A087WTS8_HUMAN,tr|A0A087WYC1|A0A087WYC1_HUMAN" 3 1637.8744 0.08 51068 17463 3 1637.877681 546.9654 Heat shock 70 kDa protein 4 OS=Homo sapiens OX=9606 GN=HSPA4 PE=1 SV=4 4.68 3003 - 909425 - - - 2.0301 - 3.449 0.513 - 606.9 1 2 0 0.0033 15 0 0 0 2.36E+06 3.09E+07 - - - 7.4891 0.9999 221125_WJC_METTL3_EV_vs_WT_F04.17464.17464.3 3.78E-05 Aug-40 R.HIDLQFSYAPR[166.11].H "sp|Q86UK7|ZN598_HUMAN,tr|H3BQQ2|H3BQQ2_HUMAN,tr|H3BPG6|H3BPG6_HUMAN" 3 1355.6862 0.57 51069 17464 3 1355.686222 452.9027 E3 ubiquitin-protein ligase ZNF598 OS=Homo sapiens OX=9606 GN=ZNF598 PE=1 SV=1 6.74 3003.1 - 852897 - - - 0.0494 - 2.176 0.44 - 108.8 1 2 0 0.0001 11 0 0 0 2.26E+06 4.00E+06 - - - 5.6543 0.9999 221125_WJC_METTL3_EV_vs_WT_F04.17465.17465.3 2.59E-05 14/48 K.QQGVLALRPYLQK.Q "sp|P56192|SYMC_HUMAN,tr|H0YHV5|H0YHV5_HUMAN" 2 1512.8776 1 51070 17465 3 1512.879353 505.2998 "Methionine--tRNA ligase, cytoplasmic OS=Homo sapiens OX=9606 GN=MARS1 PE=1 SV=2" 9.99 3003.2 - 775571 - - - 1.1277 - 2.342 0.409 - 211 1 2 0 0.0017 13 0 0 0 3.23E+07 3.22E+07 - - - 5.4068 1 221125_WJC_METTL3_EV_vs_WT_F04.17466.17466.3 1.51E-10 18/52 K.DC[160.03]GATWVVLGHSER[166.11].R "sp|P60174|TPIS_HUMAN,tr|U3KPS5|U3KPS5_HUMAN,tr|U3KQF3|U3KQF3_HUMAN,tr|U3KPZ0|U3KPZ0_HUMAN" 4 1595.739 1.32 51071 17466 3 1595.741129 532.9203 Triosephosphate isomerase OS=Homo sapiens OX=9606 GN=TPI1 PE=1 SV=4 5.32 3003.3 - 658224 - - - 1.3373 - 2.911 0.626 - 483.1 1 2 0 0.0021 14 0 0 0 5.31E+06 4.01E+06 - - - 8.3583 0.9999 221125_WJC_METTL3_EV_vs_WT_F04.17468.17468.3 1.10E-09 15/84 R.LPPPADYNKEITEGDEVEVYSR.A "sp|P51116|FXR2_HUMAN,tr|I3L1Z2|I3L1Z2_HUMAN" 2 2520.202 2.49 51073 17468 3 2520.204448 841.0746 Fragile X mental retardation syndrome-related protein 2 OS=Homo sapiens OX=9606 GN=FXR2 PE=1 SV=2 4.08 3003.6 - 646282 - - - 0.9658 - 2.905 0.642 - 196 1 2 1 0.0024 22 0 0 0 1.23E+07 4.94E+06 - - - 8.2253 0.9999 221125_WJC_METTL3_EV_vs_WT_F04.17469.17469.3 8.89E-06 16/56 K.YLDEDTIYHLQPSGR[166.11].F sp|P31153|METK2_HUMAN 1 1815.8667 1.29 51074 17469 3 1815.871994 606.2962 S-adenosylmethionine synthase isoform type-2 OS=Homo sapiens OX=9606 GN=MAT2A PE=1 SV=1 4.54 3003.7 - 583126 - - - 2.9165 - 2.549 0.473 - 231.4 1 2 0 0.0053 15 0 0 0 9.27E+07 7.21E+07 - - - 6.2536 0.9994 221125_WJC_METTL3_EV_vs_WT_F04.17470.17470.3 0.000726 Nov-44 R.YQILPLHSQIPR.E sp|Q08211|DHX9_HUMAN 1 1463.8249 1.12 51075 17470 3 1463.825727 488.9489 ATP-dependent RNA helicase A OS=Homo sapiens OX=9606 GN=DHX9 PE=1 SV=4 8.75 3003.8 - 548680 - - - 0.5759 - 2.025 0.291 - 136.2 1 2 0 0.0008 12 0 0 0 2.98E+06 2.65E+06 - - - 3.7399 0.9998 221125_WJC_METTL3_EV_vs_WT_F04.17472.17472.2 4.81E-05 14/22 R.DIK[136.11]PDNLLLDSK[136.11].G sp|Q15208|STK38_HUMAN 1 1385.7737 4.21 51077 17472 2 1385.775298 693.8941 Serine\threonine-protein kinase 38 OS=Homo sapiens OX=9606 GN=STK38 PE=1 SV=1 4.43 3004 - 496587 - - - 1.156 - 2.502 0.425 - 239.3 1 2 0 0.0016 12 0 0 0 3.41E+08 8.11E+07 - - - 4.5926 1 221125_WJC_METTL3_EV_vs_WT_F04.17473.17473.2 3.43E-08 30-Dec R.VQVQDNEGC[160.03]PVEALVK.D "sp|P21333|FLNA_HUMAN,tr|A0A7P0NMY4|A0A7P0NMY4_HUMAN,tr|Q60FE5|Q60FE5_HUMAN" 3 1783.8774 0.6 51078 17473 2 1783.864706 892.946 Filamin-A OS=Homo sapiens OX=9606 GN=FLNA PE=1 SV=4 4.14 3004.1 - 495449 - - - -7.1434 - 2.72 0.583 - 306 1 2 0 -0.0127 16 0 0 0 7.58E+06 1.26E+07 - - - 5.8031 0.9999 221125_WJC_METTL3_EV_vs_WT_F04.17474.17474.3 0.00037 Dec-40 R.K[136.11]ALDDMISTLK[136.11].K "sp|P49368|TCPG_HUMAN,tr|E9PM09|E9PM09_HUMAN,tr|Q5SZW8|Q5SZW8_HUMAN,tr|E9PRC8|E9PRC8_HUMAN,tr|B4DUR8|B4DUR8_HUMAN,tr|Q5SZX9|Q5SZX9_HUMAN,tr|E9PQ35|E9PQ35_HUMAN,tr|Q5SZX6|Q5SZX6_HUMAN" 8 1249.6923 0.23 51079 17474 3 1249.69298 417.5714 T-complex protein 1 subunit gamma OS=Homo sapiens OX=9606 GN=CCT3 PE=1 SV=4 5.96 3004.3 - 493065 - - - 0.5649 - 2.63 0.353 - 337.2 1 2 0 0.0007 11 0 0 0 2.21E+07 9.62E+07 - - - 5.2224 0.9749 221125_WJC_METTL3_EV_vs_WT_F04.17475.17475.3 0.112 Aug-36 K.K[136.11]FDDENFILK[136.11].H "sp|Q9UNP9|PPIE_HUMAN,tr|E9PEQ6|E9PEQ6_HUMAN,tr|E9PKY5|E9PKY5_HUMAN" 3 1283.6733 1.6 51080 17475 3 1283.67658 428.8984 Peptidyl-prolyl cis-trans isomerase E OS=Homo sapiens OX=9606 GN=PPIE PE=1 SV=1 4.56 3004.4 - 319718 - - - 2.5918 - 1.447 0.203 - 96.9 1 2 0 0.0033 10 0 0 0 1.86E+06 1.16E+06 - - - 1.8814 1 221125_WJC_METTL3_EV_vs_WT_F04.17477.17477.2 0.00208 15/28 R.NYILDQTNVYGSAQR[166.11].R "sp|Q9BUJ2|HNRL1_HUMAN,tr|A0A0A0MRA5|A0A0A0MRA5_HUMAN,tr|M0R3F1|M0R3F1_HUMAN,tr|B7Z4B8|B7Z4B8_HUMAN" 4 1750.8514 1.6 51081 17477 2 1750.852107 876.433 Heterogeneous nuclear ribonucleoprotein U-like protein 1 OS=Homo sapiens OX=9606 GN=HNRNPUL1 PE=1 SV=2 5.83 3004.6 - 4.36E+06 - - - 0.4141 - 2.896 0.608 - 809 1 2 0 0.0007 15 0 0 0 9.19E+07 5.73E+07 - - - 6.1457 0.9999 221125_WJC_METTL3_EV_vs_WT_F04.17480.17480.3 5.63E-05 Oct-56 R.NYILDQTNVYGSAQR.R "sp|Q9BUJ2|HNRL1_HUMAN,tr|A0A0A0MRA5|A0A0A0MRA5_HUMAN,tr|M0R3F1|M0R3F1_HUMAN,tr|B7Z4B8|B7Z4B8_HUMAN" 4 1740.8431 1.66 51084 17480 3 1740.844341 581.2883 Heterogeneous nuclear ribonucleoprotein U-like protein 1 OS=Homo sapiens OX=9606 GN=HNRNPUL1 PE=1 SV=2 5.83 3004.8 - 7.61E+06 - - - 0.706 - 1.925 0.503 - 121.2 1 2 0 0.0012 15 0 0 0 7.24E+07 4.37E+07 - - - 5.8566 1 221125_WJC_METTL3_EV_vs_WT_F04.17481.17481.3 7.64E-06 15/56 R.GALQNIIPASTGAAK.A "sp|P04406|G3P_HUMAN,tr|E7EUT5|E7EUT5_HUMAN" 2 1410.7831 1.06 51085 17481 3 1410.783531 471.2683 Glyceraldehyde-3-phosphate dehydrogenase OS=Homo sapiens OX=9606 GN=GAPDH PE=1 SV=3 8.75 3004.9 - 1.84E+06 - - - 0.3211 - 2.883 0.456 - 319.5 1 2 0 0.0005 15 0 0 0 1.27E+09 1.19E+09 - - - 6.3867 1 221125_WJC_METTL3_EV_vs_WT_F04.17482.17482.3 6.16E-05 14/56 R.GALQNIIPASTGAAK[136.11].A "sp|P04406|G3P_HUMAN,tr|E7EUT5|E7EUT5_HUMAN" 2 1418.7973 1.06 51086 17482 3 1418.795477 473.9397 Glyceraldehyde-3-phosphate dehydrogenase OS=Homo sapiens OX=9606 GN=GAPDH PE=1 SV=3 8.75 3005 - 1.51E+06 - - - -1.2694 - 2.985 0.462 - 255.7 1 2 0 -0.0018 15 0 0 0 1.27E+09 1.19E+09 - - - 6.5439 1 221125_WJC_METTL3_EV_vs_WT_F04.17483.17483.3 6.12E-08 19/60 R.DLK[136.11]PENILVTSGGTVK[136.11].L "sp|P11802|CDK4_HUMAN,tr|F8VWX7|F8VWX7_HUMAN,tr|F8VXD2|F8VXD2_HUMAN,tr|F8VZZ0|F8VZZ0_HUMAN,tr|F8VTV8|F8VTV8_HUMAN,tr|F8VYH9|F8VYH9_HUMAN,tr|F8VZ51|F8VZ51_HUMAN" 7 1685.9535 0.39 51087 17483 3 1685.956228 562.9918 Cyclin-dependent kinase 4 OS=Homo sapiens OX=9606 GN=CDK4 PE=1 SV=2 6.07 3005.1 - 944752 - - - 1.6471 - 3.04 0.521 - 498.6 1 2 0 0.0028 16 0 0 0 6.17E+06 1.58E+07 - - - 7.2007 1 221125_WJC_METTL3_EV_vs_WT_F04.17484.17484.2 1.18E-08 19/34 K.TVAGGAWTYNTTSAVTVK[136.11].S "sp|P61513|RL37A_HUMAN,tr|C9J4Z3|C9J4Z3_HUMAN" 2 1833.9352 0.95 51088 17484 2 1833.936727 917.9749 60S ribosomal protein L37a OS=Homo sapiens OX=9606 GN=RPL37A PE=1 SV=2 8.26 3005.2 - 924729 - - - 0.8174 - 3.737 0.662 - 837.5 1 2 0 0.0015 18 0 0 0 8.97E+07 9.44E+07 - - - 7.1711 1 221125_WJC_METTL3_EV_vs_WT_F04.17485.17485.3 2.78E-08 19/64 K.LC[160.03]DEQLSSQSHYDFGLR[166.11].A "sp|Q14204|DYHC1_HUMAN,tr|A0A7P0T8N2|A0A7P0T8N2_HUMAN,tr|A0A7P0T9C4|A0A7P0T9C4_HUMAN,tr|A0A7P0TBJ7|A0A7P0TBJ7_HUMAN,tr|A0A804HHY6|A0A804HHY6_HUMAN,tr|A0A7P0T9K2|A0A7P0T9K2_HUMAN,tr|A0A7P0TB64|A0A7P0TB64_HUMAN,tr|A0A2R8Y706|A0A2R8Y706_HUMAN,tr|A0A7P0T916|A0A7P0T916_HUMAN,tr|A0A7P0TB75|A0A7P0TB75_HUMAN,tr|A0A7P0T8W5|A0A7P0T8W5_HUMAN,tr|A0A7P0T9S3|A0A7P0T9S3_HUMAN,tr|A0A7P0TAF3|A0A7P0TAF3_HUMAN,tr|A0A7P0T9F1|A0A7P0T9F1_HUMAN,tr|A0A7P0TAW9|A0A7P0TAW9_HUMAN,tr|A0A2R8YGC7|A0A2R8YGC7_HUMAN,tr|A0A7P0TA13|A0A7P0TA13_HUMAN,tr|A0A7P0T934|A0A7P0T934_HUMAN,tr|A0A7P0TAV5|A0A7P0TAV5_HUMAN,tr|A0A7P0T7V5|A0A7P0T7V5_HUMAN,tr|A0A7P0T9R4|A0A7P0T9R4_HUMAN,tr|A0A2R8Y5T0|A0A2R8Y5T0_HUMAN,tr|A0A7P0T990|A0A7P0T990_HUMAN,tr|A0A7P0T942|A0A7P0T942_HUMAN,tr|A0A2R8YFZ7|A0A2R8YFZ7_HUMAN,tr|A0A7P0T825|A0A7P0T825_HUMAN,tr|A0A2R8Y6H2|A0A2R8Y6H2_HUMAN,tr|A0A7P0TAM4|A0A7P0TAM4_HUMAN" 28 2063.9246 0.68 51089 17485 3 2063.928301 688.9822 Cytoplasmic dynein 1 heavy chain 1 OS=Homo sapiens OX=9606 GN=DYNC1H1 PE=1 SV=5 4.54 3005.4 - 791394 - - - 1.7816 - 3.525 0.562 - 610.3 1 2 0 0.0037 17 0 0 0 2.43E+06 3.54E+06 - - - 7.9876 1 221125_WJC_METTL3_EV_vs_WT_F04.17486.17486.2 2.03E-08 19/34 K.TVAGGAWTYNTTSAVTVK.S "sp|P61513|RL37A_HUMAN,tr|C9J4Z3|C9J4Z3_HUMAN" 2 1825.921 0.95 51090 17486 2 1825.920545 913.9678 60S ribosomal protein L37a OS=Homo sapiens OX=9606 GN=RPL37A PE=1 SV=2 8.26 3005.5 - 674817 - - - -0.2645 - 3.73 0.658 - 979.1 1 2 0 -0.0005 18 0 0 0 8.97E+07 9.44E+07 - - - 7.1373 1 221125_WJC_METTL3_EV_vs_WT_F04.17487.17487.2 1.19E-09 14/30 R.VQVQDNEGC[160.03]PVEALVK[136.11].D "sp|P21333|FLNA_HUMAN,tr|A0A7P0NMY4|A0A7P0NMY4_HUMAN,tr|Q60FE5|Q60FE5_HUMAN" 3 1791.8916 0.69 51091 17487 2 1791.888284 896.9531 Filamin-A OS=Homo sapiens OX=9606 GN=FLNA PE=1 SV=4 4.14 3005.6 - 481909 - - - -1.8779 - 3.119 0.599 - 397.5 1 2 0 -0.0034 16 0 0 0 1.17E+07 1.69E+07 - - - 6.2608 1 221125_WJC_METTL3_EV_vs_WT_F04.17488.17488.2 2.60E-06 15/24 R.QDLADVVQVC[160.03]EGK[136.11].K "sp|Q14204|DYHC1_HUMAN,tr|A0A7P0T9C4|A0A7P0T9C4_HUMAN,tr|A0A2R8Y706|A0A2R8Y706_HUMAN,tr|A0A7P0TAW9|A0A7P0TAW9_HUMAN,tr|A0A7P0TA13|A0A7P0TA13_HUMAN,tr|A0A7P0T9R4|A0A7P0T9R4_HUMAN,tr|A0A2R8Y5T0|A0A2R8Y5T0_HUMAN" 7 1467.7119 0.2 51092 17488 2 1467.712797 734.8632 Cytoplasmic dynein 1 heavy chain 1 OS=Homo sapiens OX=9606 GN=DYNC1H1 PE=1 SV=5 4.03 3005.7 - 248376 - - - 0.6152 - 2.725 0.565 - 839.3 1 2 0 0.0009 13 0 0 0 1.47E+06 7.36E+06 - - - 5.7867 1 221125_WJC_METTL3_EV_vs_WT_F04.17493.17493.3 9.13E-06 Oct-68 K.TVAGGAWTYNTTSAVTVK.S "sp|P61513|RL37A_HUMAN,tr|C9J4Z3|C9J4Z3_HUMAN" 2 1825.921 0.75 51095 17493 3 1825.920951 609.6476 60S ribosomal protein L37a OS=Homo sapiens OX=9606 GN=RPL37A PE=1 SV=2 8.26 3006.4 - 1.49E+06 - - - -0.0422 - 2.11 0.513 - 66.3 1 2 0 -0.0001 18 0 0 0 4.54E+07 6.06E+07 - - - 6.1187 0.9999 221125_WJC_METTL3_EV_vs_WT_F04.17495.17495.3 6.90E-06 13/68 K.TVAGGAWTYNTTSAVTVK[136.11].S "sp|P61513|RL37A_HUMAN,tr|C9J4Z3|C9J4Z3_HUMAN" 2 1833.9352 1.01 51097 17495 3 1833.935193 612.319 60S ribosomal protein L37a OS=Homo sapiens OX=9606 GN=RPL37A PE=1 SV=2 8.26 3006.6 - 1.40E+06 - - - -0.0191 - 2.345 0.449 - 105.7 1 2 0 0 18 0 0 0 3.05E+07 3.02E+07 - - - 5.6682 0.9996 221125_WJC_METTL3_EV_vs_WT_F04.17496.17496.3 0.00183 16/48 K.AGQVFLEELGNHK.A sp|P09543|CN37_HUMAN 1 1440.7361 0.8 51098 17496 3 1440.734526 481.2527 "2',3'-cyclic-nucleotide 3'-phosphodiesterase OS=Homo sapiens OX=9606 GN=CNP PE=1 SV=2" 5.4 3006.7 - 1.26E+06 - - - -1.1119 - 2.666 0.25 - 392.5 1 2 0 -0.0016 13 0 0 0 1.57E+07 1.97E+07 - - - 3.9854 1 221125_WJC_METTL3_EV_vs_WT_F04.17497.17497.3 6.58E-05 Dec-44 K.QITQLLPEDLR[166.11]K[136.11].E sp|Q7Z4H3|HDDC2_HUMAN 1 1470.8525 2.47 51099 17497 3 1470.854127 491.2914 5'-deoxynucleotidase HDDC2 OS=Homo sapiens OX=9606 GN=HDDC2 PE=1 SV=1 6.07 3006.7 - 1.07E+06 - - - 1.1068 - 2.553 0.445 - 229.6 1 2 0 0.0016 12 0 0 0 6.99E+07 2.83E+07 - - - 6.0988 0.9998 221125_WJC_METTL3_EV_vs_WT_F04.17498.17498.3 0.000132 Dec-48 K.SHGLFGLNENQLR.L sp|Q96H79|ZCCHL_HUMAN 1 1483.7532 0.97 51100 17498 3 1483.754954 495.5917 Zinc finger CCCH-type antiviral protein 1-like OS=Homo sapiens OX=9606 GN=ZC3HAV1L PE=1 SV=2 6.47 3006.9 - 638866 - - - 1.199 - 2.568 0.319 - 385.4 1 2 0 0.0018 13 0 0 0 4.65E+07 4.81E+07 - - - 4.6531 0.997 221125_WJC_METTL3_EV_vs_WT_F04.17501.17501.3 0.000125 13/48 K.SHGLFGLNENQLR[166.11].L sp|Q96H79|ZCCHL_HUMAN 1 1493.7614 0.97 51103 17501 3 1494.764725 498.9278 Zinc finger CCCH-type antiviral protein 1-like OS=Homo sapiens OX=9606 GN=ZC3HAV1L PE=1 SV=2 6.47 3007.2 - 587855 - - - 671.6467 - 2.563 0.375 - 430.8 1 2 0 1.0033 13 0 0 0 4.65E+07 4.81E+07 - - - 4.9948 0.9999 221125_WJC_METTL3_EV_vs_WT_F04.17502.17502.3 3.71E-06 16/52 R.IVATK[136.11]PLYVALAQR[166.11].K "sp|Q9H361|PABP3_HUMAN,sp|P11940|PABP1_HUMAN,tr|A0A7I2YQE4|A0A7I2YQE4_HUMAN,tr|A0A7I2V649|A0A7I2V649_HUMAN,tr|H0YB86|H0YB86_HUMAN,tr|H0YAR2|H0YAR2_HUMAN,tr|E7ERJ7|E7ERJ7_HUMAN,tr|A0A7I2YQ88|A0A7I2YQ88_HUMAN,tr|A0A087WTT1|A0A087WTT1_HUMAN,tr|A0A7I2YQ90|A0A7I2YQ90_HUMAN,tr|A0A7I2V4N4|A0A7I2V4N4_HUMAN,tr|E7EQV3|E7EQV3_HUMAN" 12 1559.9518 1.43 51104 17502 3 1559.957313 520.9912 Polyadenylate-binding protein 3 OS=Homo sapiens OX=9606 GN=PABPC3 PE=1 SV=2 9.99 3007.3 - 396799 - - - 3.5219 - 2.631 0.514 - 328.9 1 2 0 0.0055 14 0 0 0 4.45E+07 3.11E+07 - - - 6.8399 0.9998 221125_WJC_METTL3_EV_vs_WT_F04.17503.17503.3 0.00408 13/48 R.AVAIDLPGLGHSK.E "sp|Q96IU4|ABHEB_HUMAN,tr|B4DQI4|B4DQI4_HUMAN" 2 1276.7139 1.77 51105 17503 3 1276.713041 426.5786 Protein ABHD14B OS=Homo sapiens OX=9606 GN=ABHD14B PE=1 SV=1 6.79 3007.4 - 381071 - - - -0.701 - 2.316 0.337 - 203.4 1 2 0 -0.0009 13 0 0 0 2.96E+07 1.67E+07 - - - 4.574 1 221125_WJC_METTL3_EV_vs_WT_F04.17507.17507.3 7.84E-10 17/52 K.HWPFMVVNDAGR[166.11]PK[136.11].V "sp|P11142|HSP7C_HUMAN,tr|E9PQQ4|E9PQQ4_HUMAN,tr|E9PNE6|E9PNE6_HUMAN,tr|E9PKE3|E9PKE3_HUMAN,tr|E9PN89|E9PN89_HUMAN,tr|E9PLF4|E9PLF4_HUMAN,tr|E9PK54|E9PK54_HUMAN,tr|E9PN25|E9PN25_HUMAN,tr|E9PPY6|E9PPY6_HUMAN,tr|E9PQK7|E9PQK7_HUMAN" 10 1670.847 0.11 51108 17507 3 1670.846714 557.9563 Heat shock cognate 71 kDa protein OS=Homo sapiens OX=9606 GN=HSPA8 PE=1 SV=1 8.75 3007.9 - 1.97E+06 - - - -0.1927 - 2.79 0.588 - 434.6 1 2 0 -0.0003 14 0 0 0 1.33E+07 1.16E+08 - - - 7.8223 1 221125_WJC_METTL3_EV_vs_WT_F04.17509.17509.3 1.92E-08 15/56 R.NYILDQTNVYGSAQR[166.11].R "sp|Q9BUJ2|HNRL1_HUMAN,tr|A0A0A0MRA5|A0A0A0MRA5_HUMAN,tr|M0R3F1|M0R3F1_HUMAN,tr|B7Z4B8|B7Z4B8_HUMAN" 4 1750.8514 1.66 51110 17509 3 1750.850406 584.6244 Heterogeneous nuclear ribonucleoprotein U-like protein 1 OS=Homo sapiens OX=9606 GN=HNRNPUL1 PE=1 SV=2 5.83 3008 - 3.93E+06 - - - -0.5574 - 2.427 0.626 - 336 1 2 0 -0.001 15 0 0 0 7.24E+07 4.37E+07 - - - 7.8326 0.9766 221125_WJC_METTL3_EV_vs_WT_F04.17511.17511.3 1.80E-06 Dec-52 R.YAILNEPFK[136.11]GEMNR[166.11].G "sp|Q14839|CHD4_HUMAN,tr|A0A2R8Y4X2|A0A2R8Y4X2_HUMAN,tr|A0A2U3TZM0|A0A2U3TZM0_HUMAN,tr|A0A2R8YD40|A0A2R8YD40_HUMAN,tr|A0A2R8Y5J0|A0A2R8Y5J0_HUMAN,tr|A0A2R8Y425|A0A2R8Y425_HUMAN,tr|A0A2R8YFK9|A0A2R8YFK9_HUMAN,tr|A0A0C4DGG9|A0A0C4DGG9_HUMAN,tr|A0A2R8YFD8|A0A2R8YFD8_HUMAN,tr|A0A2R8YDW2|A0A2R8YDW2_HUMAN,tr|A0A2R8Y7I0|A0A2R8Y7I0_HUMAN,tr|F5GWX5|F5GWX5_HUMAN,tr|A0A2R8Y7M9|A0A2R8Y7M9_HUMAN,tr|A0A2R8Y521|A0A2R8Y521_HUMAN,tr|A0A2R8YDJ9|A0A2R8YDJ9_HUMAN,tr|A0A2R8Y212|A0A2R8Y212_HUMAN" 16 1698.8518 0.51 51112 17511 3 1699.860326 567.2912 Chromodomain-helicase-DNA-binding protein 4 OS=Homo sapiens OX=9606 GN=CHD4 PE=1 SV=2 6.14 3008.1 - 1.25E+06 - - - 593.6239 - 2.425 0.482 - 118.5 1 2 1 1.0085 14 0 0 0 1.14E+07 2.25E+07 - - - 5.9886 0.8236 221125_WJC_METTL3_EV_vs_WT_F04.17512.17512.2 0.0052 24-Aug E.RVYDTVVEDLC[160.03]SR.E tr|A0A1W2PR75|A0A1W2PR75_HUMAN 1 1610.7723 341.48 51113 17512 2 1610.769567 806.3934 RNA polymerase II subunit A C-terminal domain phosphatase SSU72 OS=Homo sapiens OX=9606 GN=SSU72P8 PE=3 SV=1 4.56 3008.3 - 1.02E+06 - - - -1.6694 - 1.579 0.247 - 28.3 4 1 0 -0.0027 13 0 0 0 1.41E+08 4.14E+05 - - - 1.7679 1 221125_WJC_METTL3_EV_vs_WT_F04.17513.17513.3 9.05E-06 19/56 K.YKPYEEALLQAEAPR.L "sp|Q15020|SART3_HUMAN,tr|A0A499FI31|A0A499FI31_HUMAN" 2 1776.9046 4.23 51114 17513 3 1776.90591 593.3088 Squamous cell carcinoma antigen recognized by T-cells 3 OS=Homo sapiens OX=9606 GN=SART3 PE=1 SV=1 4.79 3008.4 - 964782 - - - 0.7091 - 3.294 0.553 - 507.8 1 2 0 0.0013 15 0 0 0 1.03E+08 2.43E+07 - - - 7.8157 0.9998 221125_WJC_METTL3_EV_vs_WT_F04.17520.17520.3 0.00498 13/44 K.QITQLLPEDLRK.E sp|Q7Z4H3|HDDC2_HUMAN 1 1452.83 2.48 51119 17520 3 1452.828262 485.284 5'-deoxynucleotidase HDDC2 OS=Homo sapiens OX=9606 GN=HDDC2 PE=1 SV=1 6.07 3009.3 - 2.70E+06 - - - -1.2162 - 2.27 0.34 - 218.1 1 2 0 -0.0018 12 0 0 0 7.03E+07 2.83E+07 - - - 4.6025 0.9997 221125_WJC_METTL3_EV_vs_WT_F04.17525.17525.3 0.00673 Dec-48 R.LVHPGVAEVVFVK.K "sp|Q9BY77|PDIP3_HUMAN,tr|F6VRR5|F6VRR5_HUMAN" 2 1392.8129 1.05 51124 17525 3 1392.814888 465.2783 Polymerase delta-interacting protein 3 OS=Homo sapiens OX=9606 GN=POLDIP3 PE=1 SV=2 6.75 3009.8 - 1.21E+06 - - - 1.4115 - 2.439 0.315 - 187 1 2 0 0.002 13 0 0 0 1.36E+07 1.30E+07 - - - 4.4687 0.993 221125_WJC_METTL3_EV_vs_WT_F04.17526.17526.2 7.31E-06 17/18 L.KPDNLLLDSK.G sp|Q15208|STK38_HUMAN 1 1141.6343 9.13 51125 17526 2 1141.634483 571.8244 Serine\threonine-protein kinase 38 OS=Homo sapiens OX=9606 GN=STK38 PE=1 SV=1 5.96 3009.9 - 796718 - - - 0.1699 - 3.261 0.353 - 971 1 1 0 0.0002 10 0 0 0 7.82E+06 8.57E+05 - - - 4.9476 0.9999 221125_WJC_METTL3_EV_vs_WT_F04.17529.17529.2 5.74E-07 22-Nov R.STGEAFVQFASK[136.11].E sp|P31942|HNRH3_HUMAN 1 1278.6336 2.6 51126 17529 2 1278.633202 640.3241 Heterogeneous nuclear ribonucleoprotein H3 OS=Homo sapiens OX=9606 GN=HNRNPH3 PE=1 SV=2 5.72 3010.3 - 1.53E+06 - - - -0.2855 - 2.464 0.495 - 626.3 1 2 0 -0.0004 12 0 0 0 5.75E+07 2.22E+07 - - - 5.0697 1 221125_WJC_METTL3_EV_vs_WT_F04.17530.17530.3 2.44E-08 15/48 R.LVHPGVAEVVFVK[136.11].K "sp|Q9BY77|PDIP3_HUMAN,tr|F6VRR5|F6VRR5_HUMAN" 2 1400.8271 1.04 51127 17530 3 1400.824126 467.9497 Polymerase delta-interacting protein 3 OS=Homo sapiens OX=9606 GN=POLDIP3 PE=1 SV=2 6.75 3010.4 - 990478 - - - -2.1387 - 2.819 0.528 - 305.1 1 2 0 -0.003 13 0 0 0 1.37E+07 1.32E+07 - - - 7.2358 0.9997 221125_WJC_METTL3_EV_vs_WT_F04.17534.17534.2 0.0181 14/22 R.SQAVQDLESLGR.H sp|Q8IYH5|ZZZ3_HUMAN 1 1301.6575 1.82 51131 17534 2 1301.654593 651.836 ZZ-type zinc finger-containing protein 3 OS=Homo sapiens OX=9606 GN=ZZZ3 PE=1 SV=1 4.37 3010.9 - 1.34E+06 - - - -2.2663 - 2.622 0.43 - 803.6 1 2 0 -0.003 12 0 0 0 3.32E+07 1.83E+07 - - - 4.7523 0.9999 221125_WJC_METTL3_EV_vs_WT_F04.17537.17537.2 1.67E-06 14/24 K.IGQLEEQLEQEAK.E sp|P35580|MYH10_HUMAN 1 1513.7624 0.97 51133 17537 2 1513.761497 757.8885 Myosin-10 OS=Homo sapiens OX=9606 GN=MYH10 PE=1 SV=3 4.09 3011.2 - 2.13E+06 - - - -0.5978 - 2.864 0.527 - 680.7 1 2 0 -0.0009 13 0 0 0 4.21E+07 4.32E+07 - - - 5.6337 0.9979 221125_WJC_METTL3_EV_vs_WT_F04.17539.17539.3 0.00765 Sep-44 R.DIKPDNLLLDSK.G sp|Q15208|STK38_HUMAN 1 1369.7453 4.23 51134 17539 3 1369.742393 457.589 Serine\threonine-protein kinase 38 OS=Homo sapiens OX=9606 GN=STK38 PE=1 SV=1 4.43 3011.5 - 5.45E+07 - - - -2.1194 - 2.056 0.246 - 137.3 1 2 0 -0.0029 12 0 0 0 9.32E+08 2.20E+08 - - - 3.2797 0.9999 221125_WJC_METTL3_EV_vs_WT_F04.17541.17541.2 3.04E-07 14/24 K.QISQAYEVLSDAK.K sp|P31689|DNJA1_HUMAN 1 1450.7304 0.35 51136 17541 2 1450.728098 726.3725 DnaJ homolog subfamily A member 1 OS=Homo sapiens OX=9606 GN=DNAJA1 PE=1 SV=2 4.37 3011.6 - 1.37E+06 - - - -1.5689 - 2.557 0.551 - 719.2 1 2 0 -0.0023 13 0 0 0 1.95E+07 5.62E+07 - - - 5.5195 1 221125_WJC_METTL3_EV_vs_WT_F04.17545.17545.2 1.30E-12 20/32 K.VVQNDAYTAPALPSSIR.T "sp|Q9BY77|PDIP3_HUMAN,tr|F6VRR5|F6VRR5_HUMAN,tr|F8WCX5|F8WCX5_HUMAN,tr|Q8WUT1|Q8WUT1_HUMAN" 4 1800.937 1.67 51138 17545 2 1800.932322 901.4758 Polymerase delta-interacting protein 3 OS=Homo sapiens OX=9606 GN=POLDIP3 PE=1 SV=2 5.81 3012.1 - 2.59E+06 - - - -2.6048 - 3.428 0.704 - 1054.7 1 2 0 -0.0047 17 0 0 0 1.28E+09 7.63E+08 - - - 7.2681 0.9999 221125_WJC_METTL3_EV_vs_WT_F04.17546.17546.2 1.09E-05 13/24 K.QISQAYEVLSDAK[136.11].K sp|P31689|DNJA1_HUMAN 1 1458.7446 0.35 51139 17546 2 1458.743173 730.3796 DnaJ homolog subfamily A member 1 OS=Homo sapiens OX=9606 GN=DNAJA1 PE=1 SV=2 4.37 3012.3 - 3.14E+06 - - - -0.9604 - 2.672 0.511 - 476.1 1 2 0 -0.0014 13 0 0 0 1.95E+07 5.62E+07 - - - 5.3373 0.9999 221125_WJC_METTL3_EV_vs_WT_F04.17548.17548.3 9.83E-06 16/52 R.IVATKPLYVALAQR.K "sp|Q9H361|PABP3_HUMAN,sp|P11940|PABP1_HUMAN,tr|A0A7I2YQE4|A0A7I2YQE4_HUMAN,tr|A0A7I2V649|A0A7I2V649_HUMAN,tr|H0YB86|H0YB86_HUMAN,tr|H0YAR2|H0YAR2_HUMAN,tr|E7ERJ7|E7ERJ7_HUMAN,tr|A0A7I2YQ88|A0A7I2YQ88_HUMAN,tr|A0A087WTT1|A0A087WTT1_HUMAN,tr|A0A7I2YQ90|A0A7I2YQ90_HUMAN,tr|A0A7I2V4N4|A0A7I2V4N4_HUMAN,tr|E7EQV3|E7EQV3_HUMAN" 12 1541.9293 1.43 51141 17548 3 1541.930135 514.9837 Polyadenylate-binding protein 3 OS=Homo sapiens OX=9606 GN=PABPC3 PE=1 SV=2 9.99 3012.4 - 4.55E+06 - - - 0.5098 - 2.218 0.426 - 338.9 1 2 0 0.0008 14 0 0 0 4.45E+07 3.11E+07 - - - 5.4063 1 221125_WJC_METTL3_EV_vs_WT_F04.17551.17551.3 4.70E-07 17/64 K.VVQNDAYTAPALPSSIR.T "sp|Q9BY77|PDIP3_HUMAN,tr|F6VRR5|F6VRR5_HUMAN,tr|F8WCX5|F8WCX5_HUMAN,tr|Q8WUT1|Q8WUT1_HUMAN" 4 1800.937 1.96 51142 17551 3 1800.932868 601.3196 Polymerase delta-interacting protein 3 OS=Homo sapiens OX=9606 GN=POLDIP3 PE=1 SV=2 5.81 3012.8 - 5.38E+06 - - - -2.3016 - 3.142 0.548 - 279.5 1 2 0 -0.0041 17 0 0 0 1.17E+09 6.00E+08 - - - 7.5408 1 221125_WJC_METTL3_EV_vs_WT_F04.17552.17552.2 1.29E-12 20/32 K.VVQNDAYTAPALPSSIR[166.11].T "sp|Q9BY77|PDIP3_HUMAN,tr|F6VRR5|F6VRR5_HUMAN,tr|F8WCX5|F8WCX5_HUMAN,tr|Q8WUT1|Q8WUT1_HUMAN" 4 1810.9453 1.67 51143 17552 2 1810.940565 906.4799 Polymerase delta-interacting protein 3 OS=Homo sapiens OX=9606 GN=POLDIP3 PE=1 SV=2 5.81 3012.9 - 4.10E+06 - - - -2.6053 - 3.389 0.639 - 1064.4 1 2 0 -0.0047 17 0 0 0 1.28E+09 7.63E+08 - - - 6.7599 1 221125_WJC_METTL3_EV_vs_WT_F04.17553.17553.3 5.73E-07 20/64 K.VVQNDAYTAPALPSSIR[166.11].T "sp|Q9BY77|PDIP3_HUMAN,tr|F6VRR5|F6VRR5_HUMAN,tr|F8WCX5|F8WCX5_HUMAN,tr|Q8WUT1|Q8WUT1_HUMAN" 4 1810.9453 1.91 51144 17553 3 1810.942824 604.6557 Polymerase delta-interacting protein 3 OS=Homo sapiens OX=9606 GN=POLDIP3 PE=1 SV=2 5.81 3013 - 4.33E+06 - - - -1.3579 - 3.468 0.539 - 391.9 1 2 0 -0.0025 17 0 0 0 1.15E+09 6.00E+08 - - - 7.6903 1 221125_WJC_METTL3_EV_vs_WT_F04.17555.17555.2 5.18E-07 15/24 K.NLNNSNLFSPVNR.D "sp|P52948|NUP98_HUMAN,tr|A0A3B3ITD8|A0A3B3ITD8_HUMAN,tr|H0YEN4|H0YEN4_HUMAN" 3 1487.7481 1.99 51146 17555 2 1488.74027 744.8813 Nuclear pore complex protein Nup98-Nup96 OS=Homo sapiens OX=9606 GN=NUP98 PE=1 SV=4 9.75 3013.2 - 1.35E+06 - - - 666.9005 - 3.06 0.619 - 891.5 1 2 0 0.9922 13 0 0 0 4.05E+08 2.04E+08 - - - 6.1718 0.9996 221125_WJC_METTL3_EV_vs_WT_F04.17556.17556.2 3.82E-06 26-Dec K.SGEEGMPDLAHVMR[166.11].L "sp|O75688|PPM1B_HUMAN,tr|B8ZZF0|B8ZZF0_HUMAN,tr|A0A3B3IS24|A0A3B3IS24_HUMAN,tr|C9JIR6|C9JIR6_HUMAN" 4 1537.6893 5.23 51147 17556 2 1537.684502 769.8519 Protein phosphatase 1B OS=Homo sapiens OX=9606 GN=PPM1B PE=1 SV=1 4.65 3013.3 - 1.10E+06 - - - -3.0995 - 2.273 0.601 - 358.1 1 2 0 -0.0048 14 0 0 0 9.95E+07 1.90E+07 - - - 5.539 0.9999 221125_WJC_METTL3_EV_vs_WT_F04.17559.17559.3 1.45E-10 17/60 K.IFVGGIK[136.11]EDTEEYNLR[166.11].D "sp|P51991|ROA3_HUMAN,tr|A0A7I2V5D8|A0A7I2V5D8_HUMAN,tr|A0A7I2V2R3|A0A7I2V2R3_HUMAN,tr|A0A7I2V4J6|A0A7I2V4J6_HUMAN,tr|A0A7I2V4G0|A0A7I2V4G0_HUMAN,tr|A0A7I2V402|A0A7I2V402_HUMAN" 6 1899.9697 1.46 51148 17559 3 1899.964825 634.3305 Heterogeneous nuclear ribonucleoprotein A3 OS=Homo sapiens OX=9606 GN=HNRNPA3 PE=1 SV=2 4.41 3013.7 - 5.13E+06 - - - -2.5727 - 3.3 0.611 - 335.4 1 2 1 -0.0049 16 0 0 0 1.65E+08 1.13E+08 - - - 8.4141 0.9515 221125_WJC_METTL3_EV_vs_WT_F04.17561.17561.3 7.42E-07 21/60 C.FDEITYVELQKEEAQK.L "sp|Q00839|HNRPU_HUMAN,tr|A0A1W2PQL0|A0A1W2PQL0_HUMAN,tr|A0A1W2PPL4|A0A1W2PPL4_HUMAN,tr|Q5RI18|Q5RI18_HUMAN,tr|A0A1W2PP35|A0A1W2PP35_HUMAN,tr|A0A1W2PPS1|A0A1W2PPS1_HUMAN,tr|A0A1W2PPH7|A0A1W2PPH7_HUMAN,tr|A0A1W2PQD4|A0A1W2PQD4_HUMAN,tr|A0A1W2PP34|A0A1W2PP34_HUMAN,tr|A0A1X7SBS1|A0A1X7SBS1_HUMAN" 10 1968.968 1.98 51150 17561 3 1968.975088 657.33 Heterogeneous nuclear ribonucleoprotein U OS=Homo sapiens OX=9606 GN=HNRNPU PE=1 SV=6 4.25 3013.9 - 2.30E+06 - - - 3.5806 - 3.076 0.52 - 529 1 1 1 0.007 16 0 0 0 3.55E+07 1.79E+07 - - - 7.2186 1 221125_WJC_METTL3_EV_vs_WT_F04.17568.17568.3 1.18E-08 16/60 K.IFVGGIKEDTEEYNLR.D "sp|P51991|ROA3_HUMAN,tr|A0A7I2V5D8|A0A7I2V5D8_HUMAN,tr|A0A7I2V2R3|A0A7I2V2R3_HUMAN,tr|A0A7I2V4J6|A0A7I2V4J6_HUMAN,tr|A0A7I2V4G0|A0A7I2V4G0_HUMAN,tr|A0A7I2V402|A0A7I2V402_HUMAN" 6 1881.9472 1.46 51155 17568 3 1881.945394 628.323 Heterogeneous nuclear ribonucleoprotein A3 OS=Homo sapiens OX=9606 GN=HNRNPA3 PE=1 SV=2 4.41 3014.8 - 8.11E+06 - - - -0.9825 - 3.194 0.609 - 335.3 1 2 1 -0.0018 16 0 0 0 1.65E+08 1.13E+08 - - - 8.3089 1 221125_WJC_METTL3_EV_vs_WT_F04.17570.17570.2 1.48E-06 16/24 K.NLNNSNLFSPVNR[166.11].D "sp|P52948|NUP98_HUMAN,tr|A0A3B3ITD8|A0A3B3ITD8_HUMAN,tr|H0YEN4|H0YEN4_HUMAN" 3 1497.7564 1.99 51157 17570 2 1497.750497 749.8855 Nuclear pore complex protein Nup98-Nup96 OS=Homo sapiens OX=9606 GN=NUP98 PE=1 SV=4 9.75 3015 - 2.38E+06 - - - -3.9145 - 3.07 0.596 - 1007.2 1 2 0 -0.0059 13 0 0 0 4.05E+08 2.04E+08 - - - 6.32 0.9998 221125_WJC_METTL3_EV_vs_WT_F04.17571.17571.3 3.31E-06 14/48 R.DVGLADR[166.11]FEEYPK[136.11].L sp|Q9HCE5|MET14_HUMAN 1 1555.7637 0.03 51158 17571 3 1555.762272 519.5952 N6-adenosine-methyltransferase non-catalytic subunit OS=Homo sapiens OX=9606 GN=METTL14 PE=1 SV=2 4.32 3015.1 - 2.19E+06 - - - -0.9455 - 2.057 0.487 - 164.2 1 2 1 -0.0015 13 0 0 0 9.42E+06 2.85E+08 - - - 5.9247 0.9998 221125_WJC_METTL3_EV_vs_WT_F04.17578.17578.3 2.14E-07 20/52 R.VEVER[166.11]DNLAEDIMR[166.11].L "sp|P08670|VIME_HUMAN,tr|B0YJC4|B0YJC4_HUMAN" 2 1707.8365 1.79 51163 17578 3 1707.832565 570.2861 Vimentin OS=Homo sapiens OX=9606 GN=VIM PE=1 SV=4 4.18 3015.9 - 1.99E+06 - - - -2.2889 - 3.015 0.529 - 623.9 1 2 1 -0.0039 14 0 0 0 9.34E+08 5.22E+08 - - - 7.3696 0.9999 221125_WJC_METTL3_EV_vs_WT_F04.17579.17579.3 4.01E-08 20/52 R.VEVERDNLAEDIMR.L "sp|P08670|VIME_HUMAN,tr|B0YJC4|B0YJC4_HUMAN" 2 1687.8199 1.79 51164 17579 3 1687.819486 563.6139 Vimentin OS=Homo sapiens OX=9606 GN=VIM PE=1 SV=4 4.18 3016 - 2.46E+06 - - - -0.2654 - 3.283 0.529 - 780.2 1 2 1 -0.0004 14 0 0 0 9.35E+08 5.22E+08 - - - 7.5969 0.9999 221125_WJC_METTL3_EV_vs_WT_F04.17580.17580.3 2.62E-06 16/44 K.SFQGEIDALSKR.S "sp|Q13948|CASP_HUMAN,sp|P39880|CUX1_HUMAN,tr|A0A2R8Y852|A0A2R8Y852_HUMAN,tr|A0A2R8YDI1|A0A2R8YDI1_HUMAN" 4 1349.6939 1.4 51165 17580 3 1349.691134 450.9053 Protein CASP OS=Homo sapiens OX=9606 GN=CUX1 PE=1 SV=2 5.79 3016.1 - 1.39E+06 - - - -2.0708 - 2.722 0.472 - 327.9 1 2 0 -0.0028 12 0 0 0 4.59E+07 3.29E+07 - - - 6.5772 1 221125_WJC_METTL3_EV_vs_WT_F04.17594.17594.3 4.71E-06 17/48 K.NLNNSNLFSPVNR.D "sp|P52948|NUP98_HUMAN,tr|A0A3B3ITD8|A0A3B3ITD8_HUMAN,tr|H0YEN4|H0YEN4_HUMAN" 3 1487.7481 2.08 51175 17594 3 1487.747561 496.9233 Nuclear pore complex protein Nup98-Nup96 OS=Homo sapiens OX=9606 GN=NUP98 PE=1 SV=4 9.75 3017.9 - 1.49E+06 - - - -0.3556 - 2.514 0.484 - 363.8 1 2 0 -0.0005 13 0 0 0 3.00E+07 1.44E+07 - - - 6.4354 0.9995 221125_WJC_METTL3_EV_vs_WT_F04.17595.17595.3 0.00772 Nov-48 R.AVAIDLPGLGHSK[136.11].E "sp|Q96IU4|ABHEB_HUMAN,tr|B4DQI4|B4DQI4_HUMAN" 2 1284.7281 1.84 51176 17595 3 1284.726467 429.25 Protein ABHD14B OS=Homo sapiens OX=9606 GN=ABHD14B PE=1 SV=1 6.79 3018.1 - 812304 - - - -1.2991 - 1.754 0.353 - 143.1 1 2 0 -0.0017 13 0 0 0 2.96E+07 1.61E+07 - - - 3.9986 1 221125_WJC_METTL3_EV_vs_WT_F04.17599.17599.2 2.34E-08 17/26 K.SGEEGMPDLAHVMR.L "sp|O75688|PPM1B_HUMAN,tr|B8ZZF0|B8ZZF0_HUMAN,tr|A0A3B3IS24|A0A3B3IS24_HUMAN,tr|C9JIR6|C9JIR6_HUMAN" 4 1527.681 5.23 51178 17599 2 1527.680102 764.8478 Protein phosphatase 1B OS=Homo sapiens OX=9606 GN=PPM1B PE=1 SV=1 4.65 3018.6 - 2.00E+06 - - - -0.5865 - 3.326 0.571 - 738.5 1 2 0 -0.0009 14 0 0 0 9.95E+07 1.90E+07 - - - 6.2739 0.9976 221125_WJC_METTL3_EV_vs_WT_F04.17602.17602.4 0.0142 Oct-66 K.LK[136.11]DYAFIHFDER[166.11].D "sp|O60506|HNRPQ_HUMAN,tr|A0A7I2YQV8|A0A7I2YQV8_HUMAN,tr|A0A7I2YQN2|A0A7I2YQN2_HUMAN,tr|A0A7I2V4Z0|A0A7I2V4Z0_HUMAN,tr|B7Z645|B7Z645_HUMAN,tr|A0A7I2V2F2|A0A7I2V2F2_HUMAN,tr|A0A7I2V346|A0A7I2V346_HUMAN,tr|A0A7I2V309|A0A7I2V309_HUMAN" 8 1570.7899 1.51 51181 17602 4 1570.787199 393.7048 Heterogeneous nuclear ribonucleoprotein Q OS=Homo sapiens OX=9606 GN=SYNCRIP PE=1 SV=2 5.38 3018.9 - 637609 - - - -1.7182 - 1.729 0.336 - 115.9 1 2 1 -0.0027 12 0 0 0 1.43E+07 9.47E+06 - - - 2.357 0.9999 221125_WJC_METTL3_EV_vs_WT_F04.17608.17608.3 7.06E-06 19/72 K.NLPPSGAVPVTGIPPHVVK[136.11].V "sp|Q13283|G3BP1_HUMAN,tr|A0A7I2V5M7|A0A7I2V5M7_HUMAN,tr|A0A7I2YQM1|A0A7I2YQM1_HUMAN,tr|A0A7P0P2U7|A0A7P0P2U7_HUMAN,tr|A0A7I2YQU8|A0A7I2YQU8_HUMAN,tr|A0A7I2V548|A0A7I2V548_HUMAN,tr|A0A7I2V651|A0A7I2V651_HUMAN,tr|A0A7I2V4D8|A0A7I2V4D8_HUMAN,tr|A0A7I2YQN9|A0A7I2YQN9_HUMAN" 9 1886.0869 1.27 51185 17608 3 1886.081526 629.7029 Ras GTPase-activating protein-binding protein 1 OS=Homo sapiens OX=9606 GN=G3BP1 PE=1 SV=1 8.76 3019.7 - 2.03E+06 - - - -2.8588 - 2.558 0.477 - 309.5 1 2 0 -0.0054 19 0 0 0 7.81E+07 6.14E+07 - - - 6.1641 1 221125_WJC_METTL3_EV_vs_WT_F04.17609.17609.2 2.09E-07 17/26 R.VEVER[166.11]DNLAEDIMR[166.11].L "sp|P08670|VIME_HUMAN,tr|B0YJC4|B0YJC4_HUMAN" 2 1707.8365 2.2 51186 17609 2 1707.831036 854.9255 Vimentin OS=Homo sapiens OX=9606 GN=VIM PE=1 SV=4 4.18 3019.8 - 1.12E+06 - - - -3.1841 - 3.098 0.536 - 349 1 2 1 -0.0054 14 0 0 0 7.64E+07 3.48E+07 - - - 5.8358 1 221125_WJC_METTL3_EV_vs_WT_F04.17611.17611.4 1.82E-08 17/78 K.HWPFMVVNDAGR[166.11]PK[136.11].V "sp|P11142|HSP7C_HUMAN,tr|E9PQQ4|E9PQQ4_HUMAN,tr|E9PNE6|E9PNE6_HUMAN,tr|E9PKE3|E9PKE3_HUMAN,tr|E9PN89|E9PN89_HUMAN,tr|E9PLF4|E9PLF4_HUMAN,tr|E9PK54|E9PK54_HUMAN,tr|E9PN25|E9PN25_HUMAN,tr|E9PPY6|E9PPY6_HUMAN,tr|E9PQK7|E9PQK7_HUMAN" 10 1670.847 0.09 51188 17611 4 1670.843037 418.719 Heat shock cognate 71 kDa protein OS=Homo sapiens OX=9606 GN=HSPA8 PE=1 SV=1 8.75 3020.1 - 624062 - - - -2.3934 - 2.664 0.565 - 260 1 2 0 -0.004 14 0 0 0 3.55E+06 3.75E+07 - - - 4.4993 0.9961 221125_WJC_METTL3_EV_vs_WT_F04.17615.17615.2 1.37E-08 17/26 R.VEVERDNLAEDIMR.L "sp|P08670|VIME_HUMAN,tr|B0YJC4|B0YJC4_HUMAN" 2 1687.8199 2.2 51190 17615 2 1687.815189 844.9172 Vimentin OS=Homo sapiens OX=9606 GN=VIM PE=1 SV=4 4.18 3020.6 - 1.81E+06 - - - -2.8113 - 3.044 0.494 - 353.2 1 2 1 -0.0047 14 0 0 0 7.64E+07 3.48E+07 - - - 5.4816 1 221125_WJC_METTL3_EV_vs_WT_F04.17616.17616.2 1.30E-09 13/20 H.NC[160.03]AVEFNFGQK[136.11].E "sp|Q00839|HNRPU_HUMAN,tr|A0A1W2PQL0|A0A1W2PQL0_HUMAN,tr|A0A1W2PPL4|A0A1W2PPL4_HUMAN,tr|A0A1W2PQ74|A0A1W2PQ74_HUMAN,tr|Q5RI18|Q5RI18_HUMAN,tr|A0A1W2PP35|A0A1W2PP35_HUMAN,tr|A0A1W2PPS1|A0A1W2PPS1_HUMAN,tr|A0A1W2PRZ7|A0A1W2PRZ7_HUMAN,tr|A0A1W2PPH7|A0A1W2PPH7_HUMAN,tr|A0A1W2PP34|A0A1W2PP34_HUMAN,tr|A0A1X7SBS1|A0A1X7SBS1_HUMAN" 11 1320.6012 1.03 51191 17616 2 1320.603296 661.3079 Heterogeneous nuclear ribonucleoprotein U OS=Homo sapiens OX=9606 GN=HNRNPU PE=1 SV=6 5.99 3020.7 - 1.28E+06 - - - 1.5713 - 2.459 0.628 - 756.7 1 1 0 0.0021 11 0 0 0 5.59E+07 5.43E+07 - - - 6.1128 0.994 221125_WJC_METTL3_EV_vs_WT_F04.17621.17621.2 5.56E-10 13/20 H.NC[160.03]AVEFNFGQK.E "sp|Q00839|HNRPU_HUMAN,tr|A0A1W2PQL0|A0A1W2PQL0_HUMAN,tr|A0A1W2PPL4|A0A1W2PPL4_HUMAN,tr|A0A1W2PQ74|A0A1W2PQ74_HUMAN,tr|Q5RI18|Q5RI18_HUMAN,tr|A0A1W2PP35|A0A1W2PP35_HUMAN,tr|A0A1W2PPS1|A0A1W2PPS1_HUMAN,tr|A0A1W2PRZ7|A0A1W2PRZ7_HUMAN,tr|A0A1W2PPH7|A0A1W2PPH7_HUMAN,tr|A0A1W2PP34|A0A1W2PP34_HUMAN,tr|A0A1X7SBS1|A0A1X7SBS1_HUMAN" 11 1312.587 1.03 51194 17621 2 1312.587303 657.3008 Heterogeneous nuclear ribonucleoprotein U OS=Homo sapiens OX=9606 GN=HNRNPU PE=1 SV=6 5.99 3021.4 - 2.45E+06 - - - 0.2148 - 2.396 0.523 - 777.2 1 1 0 0.0003 11 0 0 0 5.59E+07 5.43E+07 - - - 5.2676 0.9977 221125_WJC_METTL3_EV_vs_WT_F04.17625.17625.4 0.0852 13/66 K.LKDYAFIHFDER.D "sp|O60506|HNRPQ_HUMAN,tr|A0A7I2YQV8|A0A7I2YQV8_HUMAN,tr|A0A7I2YQN2|A0A7I2YQN2_HUMAN,tr|A0A7I2V4Z0|A0A7I2V4Z0_HUMAN,tr|B7Z645|B7Z645_HUMAN,tr|A0A7I2V2F2|A0A7I2V2F2_HUMAN,tr|A0A7I2V346|A0A7I2V346_HUMAN,tr|A0A7I2V309|A0A7I2V309_HUMAN" 8 1552.7674 1.51 51198 17625 4 1552.763384 389.1991 Heterogeneous nuclear ribonucleoprotein Q OS=Homo sapiens OX=9606 GN=SYNCRIP PE=1 SV=2 5.38 3021.8 - 550268 - - - -2.6044 - 2.379 0.359 - 174.4 1 2 1 -0.004 12 0 0 0 1.43E+07 9.47E+06 - - - 2.6776 1 221125_WJC_METTL3_EV_vs_WT_F04.17631.17631.3 2.70E-05 21/80 R.SPLRPTPVVAPSEVPAGFPQR.L sp|Q14774|HLX_HUMAN 1 2201.1957 2.97 51201 17631 3 2201.195232 734.7392 H2.0-like homeobox protein OS=Homo sapiens OX=9606 GN=HLX PE=1 SV=3 9.31 3022.6 - 1.78E+06 - - - -0.2067 - 3.825 0.578 - 325.3 1 2 0 -0.0005 21 0 0 0 4.36E+07 1.47E+07 - - - 8.2003 0.9791 221125_WJC_METTL3_EV_vs_WT_F04.17633.17633.2 0.000101 13/22 H.QNIIPASTGAAK[136.11].A "sp|O14556|G3PT_HUMAN,sp|P04406|G3P_HUMAN,tr|E7EUT5|E7EUT5_HUMAN" 3 1177.6546 1.53 51203 17633 2 1177.652877 589.8346 "Glyceraldehyde-3-phosphate dehydrogenase, testis-specific OS=Homo sapiens OX=9606 GN=GAPDHS PE=1 SV=2" 8.75 3022.9 - 423247 - - - -1.4945 - 2.669 0.308 - 575.9 1 1 0 -0.0018 12 0 0 0 4.38E+06 2.86E+06 - - - 3.8984 1 221125_WJC_METTL3_EV_vs_WT_F04.17636.17636.3 6.89E-07 18/56 K.FQSIVIGC[160.03]ALEDQK[136.11]K[136.11].L sp|O95816|BAG2_HUMAN 1 1750.9259 0.31 51204 17636 3 1750.927262 584.6492 BAG family molecular chaperone regulator 2 OS=Homo sapiens OX=9606 GN=BAG2 PE=1 SV=1 6.06 3023.2 - 2.91E+06 - - - 0.803 - 3.328 0.551 - 482.2 1 2 0 0.0014 15 0 0 0 1.75E+07 5.64E+07 - - - 7.8201 1 221125_WJC_METTL3_EV_vs_WT_F04.17640.17640.3 9.57E-09 18/56 K.R[166.11]LEITPVVC[160.03]NVEQVR[166.11].L sp|Q9UI36|DACH1_HUMAN 1 1830.9889 1.24 51208 17640 3 1830.991898 611.3369 Dachshund homolog 1 OS=Homo sapiens OX=9606 GN=DACH1 PE=1 SV=4 6.14 3023.6 - 2.06E+06 - - - 1.6412 - 3.49 0.61 - 596.2 1 2 0 0.003 15 0 0 0 6.17E+07 4.99E+07 - - - 8.6015 0.9998 221125_WJC_METTL3_EV_vs_WT_F04.17644.17644.2 0.000991 13/28 R.GALQNIIPASTGAAK[136.11].A "sp|P04406|G3P_HUMAN,tr|E7EUT5|E7EUT5_HUMAN" 2 1418.7973 1.07 51211 17644 2 1418.795245 710.4059 Glyceraldehyde-3-phosphate dehydrogenase OS=Homo sapiens OX=9606 GN=GAPDH PE=1 SV=3 8.75 3024.1 - 2.96E+08 - - - -1.4329 - 2.637 0.492 - 356.9 1 2 0 -0.002 15 0 0 0 1.52E+10 1.41E+10 - - - 5.0582 1 221125_WJC_METTL3_EV_vs_WT_F04.17648.17648.2 1.86E-10 13/34 R.SVPTSTVFYPSDGVATEK.A "sp|P29401|TKT_HUMAN,tr|A0A0B4J1R6|A0A0B4J1R6_HUMAN" 2 1883.9153 1.24 51214 17648 2 1883.918626 942.9649 Transketolase OS=Homo sapiens OX=9606 GN=TKT PE=1 SV=3 4.37 3024.5 - 881425 - - - 1.7793 - 2.766 0.641 - 343 1 2 0 0.0034 18 0 0 0 1.62E+07 1.30E+07 - - - 6.2757 1 221125_WJC_METTL3_EV_vs_WT_F04.17653.17653.3 1.31E-10 14/40 R.THSDQFLVAFK[136.11].E sp|P36542|ATPG_HUMAN 1 1299.6703 1.11 51217 17653 3 1299.666976 434.2307 "ATP synthase subunit gamma, mitochondrial OS=Homo sapiens OX=9606 GN=ATP5F1C PE=1 SV=1" 6.41 3025.1 - 1.65E+06 - - - -2.5476 - 2.563 0.658 - 282.3 1 2 0 -0.0033 11 0 0 0 1.08E+08 9.75E+07 - - - 8.5489 1 221125_WJC_METTL3_EV_vs_WT_F04.17654.17654.3 2.21E-12 15/40 R.THSDQFLVAFK.E sp|P36542|ATPG_HUMAN 1 1291.6561 1.11 51218 17654 3 1291.652729 431.5593 "ATP synthase subunit gamma, mitochondrial OS=Homo sapiens OX=9606 GN=ATP5F1C PE=1 SV=1" 6.41 3025.2 - 1.08E+06 - - - -2.5998 - 2.667 0.664 - 316.9 1 2 0 -0.0034 11 0 0 0 1.08E+08 9.74E+07 - - - 8.7287 0.9972 221125_WJC_METTL3_EV_vs_WT_F04.17656.17656.2 3.52E-07 13/24 R.DVGLADR[166.11]FEEYPK[136.11].L sp|Q9HCE5|MET14_HUMAN 1 1555.7637 0.001 51220 17656 2 1555.760324 778.8891 N6-adenosine-methyltransferase non-catalytic subunit OS=Homo sapiens OX=9606 GN=METTL14 PE=1 SV=2 4.32 3025.5 - 1.46E+06 - - - -2.1976 - 2.358 0.534 - 401.3 1 2 1 -0.0034 13 0 0 0 0.00E+00 5.16E+07 - - - 5.1857 1 221125_WJC_METTL3_EV_vs_WT_F04.17659.17659.2 3.59E-08 16/28 R.GALQNIIPASTGAAK.A "sp|P04406|G3P_HUMAN,tr|E7EUT5|E7EUT5_HUMAN" 2 1410.7831 1.07 51222 17659 2 1410.782469 706.3988 Glyceraldehyde-3-phosphate dehydrogenase OS=Homo sapiens OX=9606 GN=GAPDH PE=1 SV=3 8.75 3025.9 - 3.83E+08 - - - -0.4317 - 2.824 0.595 - 649.4 1 2 0 -0.0006 15 0 0 0 1.52E+10 1.41E+10 - - - 5.9878 0.9999 221125_WJC_METTL3_EV_vs_WT_F04.17661.17661.3 0.000608 14/56 K.MVHGNITPENIILNK[136.11].S "sp|Q6P3W7|SCYL2_HUMAN,tr|F8VSC5|F8VSC5_HUMAN,tr|A0A0U1RQQ9|A0A0U1RQQ9_HUMAN,tr|F8VPW3|F8VPW3_HUMAN" 4 1699.9171 2.36 51223 17661 3 1699.912941 567.6463 SCY1-like protein 2 OS=Homo sapiens OX=9606 GN=SCYL2 PE=1 SV=1 6.5 3026.1 - 2.95E+06 - - - -2.4325 - 2.714 0.438 - 376.1 1 2 0 -0.0041 15 0 0 0 1.26E+08 5.32E+07 - - - 6.0274 1 221125_WJC_METTL3_EV_vs_WT_F04.17662.17662.3 5.53E-08 24/80 R.VTGEADVEFATHEDAVAAMSK[136.11].D "sp|P31943|HNRH1_HUMAN,tr|H0YBD7|H0YBD7_HUMAN,tr|H0YB39|H0YB39_HUMAN,tr|H0YBG7|H0YBG7_HUMAN,tr|E9PCY7|E9PCY7_HUMAN,tr|G8JLB6|G8JLB6_HUMAN" 6 2185.0089 1.19 51224 17662 3 2185.003679 729.3436 Heterogeneous nuclear ribonucleoprotein H OS=Homo sapiens OX=9606 GN=HNRNPH1 PE=1 SV=4 4.17 3026.1 - 2.03E+06 - - - -2.373 - 4.259 0.636 - 508.4 1 2 0 -0.0052 21 0 0 0 1.46E+08 1.23E+08 - - - 9.1033 1 221125_WJC_METTL3_EV_vs_WT_F04.17663.17663.3 4.06E-14 26/80 R.VTGEADVEFATHEDAVAAMSK.D "sp|P31943|HNRH1_HUMAN,tr|H0YBD7|H0YBD7_HUMAN,tr|H0YB39|H0YB39_HUMAN,tr|H0YBG7|H0YBG7_HUMAN,tr|E9PCY7|E9PCY7_HUMAN,tr|G8JLB6|G8JLB6_HUMAN" 6 2176.9947 1.19 51225 17663 3 2176.98864 726.6722 Heterogeneous nuclear ribonucleoprotein H OS=Homo sapiens OX=9606 GN=HNRNPH1 PE=1 SV=4 4.17 3026.2 - 2.51E+06 - - - -2.7671 - 5.048 0.713 - 860.8 1 2 0 -0.006 21 0 0 0 1.46E+08 1.23E+08 - - - 10.369 0.9999 221125_WJC_METTL3_EV_vs_WT_F04.17664.17664.2 1.65E-07 15/34 R.SVPTSTVFYPSDGVATEK[136.11].A "sp|P29401|TKT_HUMAN,tr|A0A0B4J1R6|A0A0B4J1R6_HUMAN" 2 1891.9295 1.24 51226 17664 2 1891.927545 946.972 Transketolase OS=Homo sapiens OX=9606 GN=TKT PE=1 SV=3 4.37 3026.4 - 574681 - - - -1.0196 - 2.712 0.469 - 424.6 1 2 0 -0.0019 18 0 0 0 1.62E+07 1.30E+07 - - - 4.9573 0.8229 221125_WJC_METTL3_EV_vs_WT_F04.17665.17665.3 0.225 Oct-56 K.VLEMDPLPSSKPFQK.Y sp|Q96SI9|STRBP_HUMAN 1 1714.8964 0.65 51227 17665 3 1714.894741 572.6394 Spermatid perinuclear RNA-binding protein OS=Homo sapiens OX=9606 GN=STRBP PE=1 SV=1 6.04 3026.5 - 795336 - - - -0.9639 - 1.751 0.008 - 103.2 1 2 0 -0.0017 15 0 0 0 7.56E+06 1.16E+07 - - - 0.0905 0.9999 221125_WJC_METTL3_EV_vs_WT_F04.17669.17669.3 0.00016 15/72 K.NLPPSGAVPVTGIPPHVVK.V "sp|Q13283|G3BP1_HUMAN,tr|A0A7I2V5M7|A0A7I2V5M7_HUMAN,tr|A0A7I2YQM1|A0A7I2YQM1_HUMAN,tr|A0A7P0P2U7|A0A7P0P2U7_HUMAN,tr|A0A7I2YQU8|A0A7I2YQU8_HUMAN,tr|A0A7I2V548|A0A7I2V548_HUMAN,tr|A0A7I2V651|A0A7I2V651_HUMAN,tr|A0A7I2V4D8|A0A7I2V4D8_HUMAN,tr|A0A7I2YQN9|A0A7I2YQN9_HUMAN" 9 1878.0727 1.32 51229 17669 3 1878.068691 627.0315 Ras GTPase-activating protein-binding protein 1 OS=Homo sapiens OX=9606 GN=G3BP1 PE=1 SV=1 8.76 3027 - 2.41E+06 - - - -2.1442 - 2.559 0.418 - 174.3 1 2 0 -0.004 19 0 0 0 8.35E+07 6.34E+07 - - - 5.5076 0.9993 221125_WJC_METTL3_EV_vs_WT_F04.17670.17670.3 7.09E-07 18/68 R.TEIVFTGEKEQLAQAVAR.L "sp|Q00341|VIGLN_HUMAN,tr|A0A024R4E5|A0A024R4E5_HUMAN,tr|H7C0A4|H7C0A4_HUMAN,tr|H0Y394|H0Y394_HUMAN" 4 1989.0531 1.71 51230 17670 3 1989.062673 664.025 Vigilin OS=Homo sapiens OX=9606 GN=HDLBP PE=1 SV=2 4.78 3027.1 - 1.43E+06 - - - 4.8103 - 3.545 0.579 - 341 1 2 1 0.0096 18 0 0 0 2.40E+07 1.40E+07 - - - 8.1439 1 221125_WJC_METTL3_EV_vs_WT_F04.17671.17671.2 5.48E-08 17/20 R.THSDQFLVAFK[136.11].E sp|P36542|ATPG_HUMAN 1 1299.6703 1.09 51231 17671 2 1299.669382 650.8424 "ATP synthase subunit gamma, mitochondrial OS=Homo sapiens OX=9606 GN=ATP5F1C PE=1 SV=1" 6.41 3027.2 - 1.47E+06 - - - -0.6963 - 3.169 0.608 - 1149.9 1 2 0 -0.0009 11 0 0 0 3.37E+07 3.11E+07 - - - 6.6517 0.9999 221125_WJC_METTL3_EV_vs_WT_F04.17672.17672.3 0.000234 Oct-40 K.K[136.11]GAYDIFLNAK[136.11].E "sp|P42704|LPPRC_HUMAN,tr|A0A804HI14|A0A804HI14_HUMAN,tr|A0A804HL40|A0A804HL40_HUMAN,tr|A0A804HKJ0|A0A804HKJ0_HUMAN,tr|A0A804HKR3|A0A804HKR3_HUMAN,tr|A0A804HIN4|A0A804HIN4_HUMAN,tr|A0A804HLG8|A0A804HLG8_HUMAN,tr|A0A804HI40|A0A804HI40_HUMAN,tr|A0A804HJZ1|A0A804HJZ1_HUMAN,tr|A0A804HIQ7|A0A804HIQ7_HUMAN,tr|A0A804HK30|A0A804HK30_HUMAN,tr|A0A804HKI2|A0A804HKI2_HUMAN,tr|A0A804HJI0|A0A804HJI0_HUMAN,tr|A0A804HIG4|A0A804HIG4_HUMAN" 14 1254.6943 0.73 51232 17672 3 1254.693329 419.2387 "Leucine-rich PPR motif-containing protein, mitochondrial OS=Homo sapiens OX=9606 GN=LRPPRC PE=1 SV=3" 8.5 3027.4 - 837419 - - - -0.7922 - 1.818 0.446 - 123.7 1 2 0 -0.001 11 0 0 0 8.31E+06 1.14E+07 - - - 5.2103 0.9664 221125_WJC_METTL3_EV_vs_WT_F04.17673.17673.2 25.9 12-Jul K.IGIEIIK.R "sp|P10809|CH60_HUMAN,tr|A0A7I2V2X6|A0A7I2V2X6_HUMAN,tr|A0A7I2YQK6|A0A7I2YQK6_HUMAN,tr|A0A7I2V599|A0A7I2V599_HUMAN" 4 784.5058 1.4 51233 17673 2 784.503666 393.2602 "60 kDa heat shock protein, mitochondrial OS=Homo sapiens OX=9606 GN=HSPD1 PE=1 SV=2" 6 3027.5 - 694391 - - - -2.7724 - 1.748 0.001 - 113.8 2 2 0 -0.0022 7 0 0 0 7.49E+06 5.33E+06 - - - 0.6828 0.9998 221125_WJC_METTL3_EV_vs_WT_F04.17674.17674.3 3.48E-06 18/60 R.LQAYHTQTTPLIEYYR.K "sp|P54819|KAD2_HUMAN,tr|F8VY04|F8VY04_HUMAN,tr|F8W1A4|F8W1A4_HUMAN,tr|A0A5K1VW67|A0A5K1VW67_HUMAN" 4 1996.0054 1.11 51234 17674 3 1996.013796 666.3424 "Adenylate kinase 2, mitochondrial OS=Homo sapiens OX=9606 GN=AK2 PE=1 SV=2" 6.75 3027.6 - 683577 - - - 4.1929 - 3.445 0.492 - 465.8 1 2 0 0.0084 16 0 0 0 6.45E+06 5.81E+06 - - - 7.1968 0.9991 221125_WJC_METTL3_EV_vs_WT_F04.17676.17676.3 0.0396 Sep-36 R.DSFPWEVPKK.L sp|P31153|METK2_HUMAN 1 1231.6237 1.09 51236 17676 3 1231.621446 411.5485 S-adenosylmethionine synthase isoform type-2 OS=Homo sapiens OX=9606 GN=MAT2A PE=1 SV=1 6.07 3027.9 - 578607 - - - -1.8496 - 1.7 0.328 - 78.9 1 2 0 -0.0023 10 0 0 0 1.27E+07 1.17E+07 - - - 3.7459 0.9999 221125_WJC_METTL3_EV_vs_WT_F04.17677.17677.2 8.51E-10 14/28 R.GENLVSMTVEGPPPK[136.11].D "sp|P63162|RSMN_HUMAN,sp|P14678|RSMB_HUMAN,tr|J3QLE5|J3QLE5_HUMAN" 3 1561.7901 1.04 51237 17677 2 1561.788383 781.9023 Small nuclear ribonucleoprotein-associated protein N OS=Homo sapiens OX=9606 GN=SNRPN PE=1 SV=1 4.53 3028 - 534495 - - - -1.1276 - 2.526 0.572 - 597.4 1 2 0 -0.0018 15 0 0 0 2.45E+07 2.35E+07 - - - 5.5434 1 221125_WJC_METTL3_EV_vs_WT_F04.17679.17679.3 2.19E-08 16/52 K.SGEEGMPDLAHVMR.L "sp|O75688|PPM1B_HUMAN,tr|B8ZZF0|B8ZZF0_HUMAN,tr|A0A3B3IS24|A0A3B3IS24_HUMAN,tr|C9JIR6|C9JIR6_HUMAN" 4 1527.681 3.53 51238 17679 3 1527.681862 510.2343 Protein phosphatase 1B OS=Homo sapiens OX=9606 GN=PPM1B PE=1 SV=1 4.65 3028.2 - 736480 - - - 0.5656 - 3.003 0.57 - 511 1 2 0 0.0009 14 0 0 0 1.04E+09 2.94E+08 - - - 7.817 1 221125_WJC_METTL3_EV_vs_WT_F04.17681.17681.2 8.00E-09 17/20 R.THSDQFLVAFK.E sp|P36542|ATPG_HUMAN 1 1291.6561 1.09 51239 17681 2 1291.654918 646.8353 "ATP synthase subunit gamma, mitochondrial OS=Homo sapiens OX=9606 GN=ATP5F1C PE=1 SV=1" 6.41 3028.5 - 2.65E+06 - - - -0.905 - 3.128 0.605 - 1167.3 1 2 0 -0.0012 11 0 0 0 3.37E+07 3.11E+07 - - - 6.5942 1 221125_WJC_METTL3_EV_vs_WT_F04.17682.17682.3 1.25E-05 18/68 R.DEATAAVIDLNDRPIGSR.K sp|Q9NTZ6|RBM12_HUMAN 1 1911.965 1.18 51240 17682 3 1911.967678 638.3289 RNA-binding protein 12 OS=Homo sapiens OX=9606 GN=RBM12 PE=1 SV=1 4.23 3028.6 - 1.12E+06 - - - 1.3907 - 3.185 0.486 - 447.6 1 2 0 0.0027 18 0 0 0 1.36E+07 1.15E+07 - - - 6.8423 1 221125_WJC_METTL3_EV_vs_WT_F04.17684.17684.3 1.20E-11 24/68 R.TEIVFTGEK[136.11]EQLAQAVAR[166.11].L "sp|Q00341|VIGLN_HUMAN,tr|A0A024R4E5|A0A024R4E5_HUMAN,tr|H7C0A4|H7C0A4_HUMAN,tr|H0Y394|H0Y394_HUMAN" 4 2007.0756 1.71 51242 17684 3 2007.078791 670.0325 Vigilin OS=Homo sapiens OX=9606 GN=HDLBP PE=1 SV=2 4.78 3028.7 - 2.03E+06 - - - 1.6023 - 3.64 0.627 - 693.8 1 2 1 0.0032 18 0 0 0 2.40E+07 1.40E+07 - - - 8.7467 0.9517 221125_WJC_METTL3_EV_vs_WT_F04.17685.17685.3 0.229 13/64 R.SPAAAMPGHRTTPEKSK.D tr|A0A2R8YDV1|A0A2R8YDV1_HUMAN 1 1764.8941 257.87 51243 17685 3 1764.895766 589.3053 Potassium voltage-gated channel subfamily KQT member 1 OS=Homo sapiens OX=9606 GN=KCNQ1 PE=1 SV=1 9.99 3028.8 - 1.59E+06 - - - 0.9428 - 1.738 0.167 - 134.8 1 2 2 0.0017 17 0 0 0 1.81E+07 7.01E+04 - - - 1.7978 0.9986 221125_WJC_METTL3_EV_vs_WT_F04.17689.17689.3 0.0103 Jul-36 R.DSFPWEVPK[136.11]K[136.11].L sp|P31153|METK2_HUMAN 1 1247.6521 1.09 51247 17689 3 1247.650554 416.8913 S-adenosylmethionine synthase isoform type-2 OS=Homo sapiens OX=9606 GN=MAT2A PE=1 SV=1 6.07 3029.3 - 882406 - - - -1.2584 - 1.466 0.329 - 53.2 2 2 0 -0.0016 10 0 0 0 1.27E+07 1.17E+07 - - - 3.1854 1 221125_WJC_METTL3_EV_vs_WT_F04.17690.17690.2 2.58E-08 17/28 K.AGPGSLELC[160.03]GLPSQK[136.11].T sp|Q14684|RRP1B_HUMAN 1 1520.7748 0.97 51248 17690 2 1520.771934 761.3947 Ribosomal RNA processing protein 1 homolog B OS=Homo sapiens OX=9606 GN=RRP1B PE=1 SV=3 6.04 3029.4 - 854597 - - - -1.9036 - 2.982 0.604 - 651.7 1 2 0 -0.0029 15 0 0 0 1.23E+07 1.27E+07 - - - 6.1874 1 221125_WJC_METTL3_EV_vs_WT_F04.17691.17691.2 2.35E-08 14/28 K.AGPGSLELC[160.03]GLPSQK.T sp|Q14684|RRP1B_HUMAN 1 1512.7606 0.97 51249 17691 2 1512.756883 757.3876 Ribosomal RNA processing protein 1 homolog B OS=Homo sapiens OX=9606 GN=RRP1B PE=1 SV=3 6.04 3029.5 - 684785 - - - -2.4763 - 2.939 0.569 - 434.3 1 2 0 -0.0037 15 0 0 0 1.23E+07 1.27E+07 - - - 5.8929 0.9999 221125_WJC_METTL3_EV_vs_WT_F04.17693.17693.3 3.35E-05 Nov-48 K.IVHAFDMEDLGDK.A sp|Q9NZ45|CISD1_HUMAN 1 1488.6919 1.37 51251 17693 3 1488.690031 497.2379 CDGSH iron-sulfur domain-containing protein 1 OS=Homo sapiens OX=9606 GN=CISD1 PE=1 SV=1 4.22 3029.8 - 567372 - - - -1.242 - 1.949 0.44 - 151 1 2 0 -0.0018 13 0 0 0 4.49E+06 3.28E+06 - - - 5.2543 0.999 221125_WJC_METTL3_EV_vs_WT_F04.17694.17694.3 0.00473 Sep-52 R.ETSHVTMVVAELEK.T "sp|Q7L5Y9|MAEA_HUMAN,tr|D6REW7|D6REW7_HUMAN,tr|D6RA86|D6RA86_HUMAN,tr|B4DVN3|B4DVN3_HUMAN,tr|D6RIB6|D6RIB6_HUMAN,tr|E7ESC7|E7ESC7_HUMAN,tr|D6RDW4|D6RDW4_HUMAN,tr|D6RE80|D6RE80_HUMAN" 8 1571.7865 1.34 51252 17694 3 1571.783068 524.9361 E3 ubiquitin-protein transferase MAEA OS=Homo sapiens OX=9606 GN=MAEA PE=1 SV=1 4.75 3029.9 - 419800 - - - -2.1892 - 2.006 0.307 - 84.2 1 2 0 -0.0034 14 0 0 0 2.17E+06 1.62E+06 - - - 3.8118 1 221125_WJC_METTL3_EV_vs_WT_F04.17698.17698.2 5.16E-08 13/24 K.LTFDSSFSPNTGK.K "sp|P21796|VDAC1_HUMAN,tr|C9JI87|C9JI87_HUMAN" 2 1399.662 1.1 51254 17698 2 1399.662651 700.8383 Voltage-dependent anion-selective channel protein 1 OS=Homo sapiens OX=9606 GN=VDAC1 PE=1 SV=2 5.84 3030.5 - 6.44E+06 - - - 0.4937 - 2.539 0.633 - 588.4 1 2 0 0.0007 13 0 0 0 8.22E+07 7.47E+07 - - - 6.1075 1 221125_WJC_METTL3_EV_vs_WT_F04.17700.17700.3 0.000307 16/56 K.MVHGNITPENIILNK.S "sp|Q6P3W7|SCYL2_HUMAN,tr|F8VSC5|F8VSC5_HUMAN,tr|A0A0U1RQQ9|A0A0U1RQQ9_HUMAN,tr|F8VPW3|F8VPW3_HUMAN" 4 1691.9029 2.36 51256 17700 3 1691.903028 564.9749 SCY1-like protein 2 OS=Homo sapiens OX=9606 GN=SCYL2 PE=1 SV=1 6.5 3030.7 - 3.11E+06 - - - 0.0898 - 3.055 0.487 - 531.2 1 2 0 0.0002 15 0 0 0 1.26E+08 5.32E+07 - - - 6.8836 0.9999 221125_WJC_METTL3_EV_vs_WT_F04.17701.17701.3 0.000601 Nov-44 K.LQWFQNHLDPQK[136.11].K "sp|Q96EY4|TMA16_HUMAN,tr|H0Y9X1|H0Y9X1_HUMAN,tr|D6RC31|D6RC31_HUMAN,tr|D6RE67|D6RE67_HUMAN,tr|D6RA57|D6RA57_HUMAN" 5 1560.7929 0.69 51257 17701 3 1560.791322 521.2716 Translation machinery-associated protein 16 OS=Homo sapiens OX=9606 GN=TMA16 PE=1 SV=2 6.74 3030.7 - 2.62E+06 - - - -0.9867 - 1.91 0.409 - 139.9 1 2 0 -0.0015 12 0 0 0 2.94E+07 4.27E+07 - - - 4.8932 1 221125_WJC_METTL3_EV_vs_WT_F04.17702.17702.3 2.60E-07 19/40 K.QEVAVFVFDKK.L "sp|Q6P3W7|SCYL2_HUMAN,tr|F8VSC5|F8VSC5_HUMAN,tr|A0A0U1RQQ9|A0A0U1RQQ9_HUMAN" 3 1308.7078 1.48 51258 17702 3 1308.706059 437.2432 SCY1-like protein 2 OS=Homo sapiens OX=9606 GN=SCYL2 PE=1 SV=1 6.07 3030.9 - 1.27E+06 - - - -1.3212 - 2.826 0.584 - 420.3 1 2 0 -0.0017 11 0 0 0 1.30E+07 8.78E+06 - - - 8.0018 1 221125_WJC_METTL3_EV_vs_WT_F04.17703.17703.3 1.87E-05 15/40 K.QEVAVFVFDK[136.11]K[136.11].L "sp|Q6P3W7|SCYL2_HUMAN,tr|F8VSC5|F8VSC5_HUMAN,tr|A0A0U1RQQ9|A0A0U1RQQ9_HUMAN" 3 1324.7362 1.43 51259 17703 3 1324.735066 442.586 SCY1-like protein 2 OS=Homo sapiens OX=9606 GN=SCYL2 PE=1 SV=1 6.07 3031 - 852820 - - - -0.847 - 2.336 0.513 - 274.6 1 2 0 -0.0011 11 0 0 0 1.30E+07 9.05E+06 - - - 6.6694 0.9996 221125_WJC_METTL3_EV_vs_WT_F04.17704.17704.2 6.31E-09 14/30 K.EGVQGPLNVSLSEEGK.S sp|P12270|TPR_HUMAN 1 1641.821 3.5 51260 17704 2 1641.825695 821.9178 Nucleoprotein TPR OS=Homo sapiens OX=9606 GN=TPR PE=1 SV=3 4.25 3031.1 - 794860 - - - 2.8718 - 2.741 0.496 - 737.4 1 2 0 0.0047 16 0 0 0 1.75E+07 5.01E+06 - - - 5.182 1 221125_WJC_METTL3_EV_vs_WT_F04.17708.17708.2 2.70E-06 16/30 R.QYTSPEEIDAQLQAEK.Q "sp|Q13442|HAP28_HUMAN,tr|F8WBW6|F8WBW6_HUMAN" 2 1848.8741 0.6 51263 17708 2 1848.876903 925.4443 28 kDa heat- and acid-stable phosphoprotein OS=Homo sapiens OX=9606 GN=PDAP1 PE=1 SV=1 4 3031.6 - 540686 - - - 1.4955 - 3.378 0.621 - 982.4 1 2 0 0.0028 16 0 0 0 1.04E+07 1.74E+07 - - - 6.6196 1 221125_WJC_METTL3_EV_vs_WT_F04.17710.17710.2 9.15E-06 14/26 K.QQEPVTSTSLVFGK[136.11].K sp|P49790|NU153_HUMAN 1 1527.8024 1.3 51264 17710 2 1527.802141 764.9085 Nuclear pore complex protein Nup153 OS=Homo sapiens OX=9606 GN=NUP153 PE=1 SV=2 6 3031.8 - 1.09E+06 - - - -0.1846 - 2.827 0.572 - 738.9 1 2 0 -0.0003 14 0 0 0 2.02E+07 1.56E+07 - - - 5.8736 0.9999 221125_WJC_METTL3_EV_vs_WT_F04.17713.17713.3 1.18E-05 14/56 K.MAFRPGVVDLPEENR.E "sp|O60216|RAD21_HUMAN,tr|E5RJW1|E5RJW1_HUMAN,tr|E5RFV8|E5RFV8_HUMAN,tr|E5RJK5|E5RJK5_HUMAN,tr|E5RIN7|E5RIN7_HUMAN" 5 1728.8617 0.36 51267 17713 3 1728.85827 577.2945 Double-strand-break repair protein rad21 homolog OS=Homo sapiens OX=9606 GN=RAD21 PE=1 SV=2 4.68 3032.1 - 736181 - - - -2.0065 - 2.333 0.418 - 157.9 1 2 0 -0.0035 15 0 0 0 4.44E+06 1.24E+07 - - - 5.4099 0.9998 221125_WJC_METTL3_EV_vs_WT_F04.17715.17715.3 9.59E-07 14/64 K.LLHSFHSELPVLSDSER.D "sp|Q99567|NUP88_HUMAN,tr|J3KMX1|J3KMX1_HUMAN" 2 1964.9956 3.2 51269 17715 3 1965.001733 656.0058 Nuclear pore complex protein Nup88 OS=Homo sapiens OX=9606 GN=NUP88 PE=1 SV=2 5.27 3032.4 - 526911 - - - 3.1262 - 2.783 0.454 - 218.9 1 2 0 0.0061 17 0 0 0 1.34E+07 4.18E+06 - - - 6.1857 0.9999 221125_WJC_METTL3_EV_vs_WT_F04.17716.17716.3 5.56E-06 Nov-44 K.SLEDVTAEYIHK.A sp|Q9P0K7|RAI14_HUMAN 1 1403.6933 0.75 51270 17716 3 1403.695067 468.905 Ankycorbin OS=Homo sapiens OX=9606 GN=RAI14 PE=1 SV=2 4.65 3032.5 - 509387 - - - 1.2873 - 1.946 0.445 - 104.6 1 2 0 0.0018 12 0 0 0 2.55E+06 3.39E+06 - - - 5.3462 1 221125_WJC_METTL3_EV_vs_WT_F04.17717.17717.3 5.31E-08 16/44 K.APIQDIWYHEDR.L "sp|Q9Y3D9|RT23_HUMAN,tr|J3QLR8|J3QLR8_HUMAN" 2 1541.7263 1 51271 17717 3 1541.72893 514.916 "28S ribosomal protein S23, mitochondrial OS=Homo sapiens OX=9606 GN=MRPS23 PE=1 SV=2" 4.54 3032.7 - 434063 - - - 1.7111 - 3.184 0.594 - 503.1 1 2 0 0.0026 12 0 0 0 1.25E+07 1.25E+07 - - - 8.372 1 221125_WJC_METTL3_EV_vs_WT_F04.17721.17721.2 5.73E-08 Nov-32 R.AGIATQFSTANGQVNLR[166.11].G "sp|Q9UQR1|ZN148_HUMAN,tr|G5E9X2|G5E9X2_HUMAN" 2 1756.9096 0.14 51275 17721 2 1756.907134 879.4621 Zinc finger protein 148 OS=Homo sapiens OX=9606 GN=ZNF148 PE=1 SV=2 9.79 3033.2 - 265112 - - - -1.3842 - 2.784 0.625 - 374.6 1 2 0 -0.0024 17 0 0 0 3.16E+05 2.27E+06 - - - 6.1738 1 221125_WJC_METTL3_EV_vs_WT_F04.17725.17725.3 5.11E-05 14/64 K.LTEVPVEPVLTVHPESK.S sp|Q9H307|PININ_HUMAN 1 1873.0197 2.39 51278 17725 3 1873.022179 625.3472 Pinin OS=Homo sapiens OX=9606 GN=PNN PE=1 SV=5 4.75 3033.6 - 3.32E+06 - - - 1.3342 - 2.362 0.505 - 141.7 1 2 0 0.0025 17 0 0 0 6.22E+07 2.60E+07 - - - 6.3409 1 221125_WJC_METTL3_EV_vs_WT_F04.17726.17726.2 8.03E-09 14/26 K.QQEPVTSTSLVFGK.K sp|P49790|NU153_HUMAN 1 1519.7882 1.3 51279 17726 2 1519.789403 760.9014 Nuclear pore complex protein Nup153 OS=Homo sapiens OX=9606 GN=NUP153 PE=1 SV=2 6 3033.7 - 2.20E+06 - - - 0.7764 - 2.895 0.611 - 731.7 1 2 0 0.0012 14 0 0 0 2.02E+07 1.56E+07 - - - 6.221 1 221125_WJC_METTL3_EV_vs_WT_F04.17727.17727.3 1.70E-12 18/68 K.MVMIQDGPLPTGADK[136.11]PLR[166.11].L sp|Q96I24|FUBP3_HUMAN 1 1956.0292 2.03 51280 17727 3 1956.030774 653.017 Far upstream element-binding protein 3 OS=Homo sapiens OX=9606 GN=FUBP3 PE=1 SV=2 5.71 3033.7 - 1.77E+06 - - - 0.8257 - 3.436 0.655 - 367.2 1 2 0 0.0016 18 0 0 0 6.88E+07 3.39E+07 - - - 8.9157 1 221125_WJC_METTL3_EV_vs_WT_F04.17730.17730.2 7.64E-09 16/30 R.QYTSPEEIDAQLQAEK[136.11].Q "sp|Q13442|HAP28_HUMAN,tr|F8WBW6|F8WBW6_HUMAN" 2 1856.8883 0.6 51283 17730 2 1856.894821 929.4514 28 kDa heat- and acid-stable phosphoprotein OS=Homo sapiens OX=9606 GN=PDAP1 PE=1 SV=1 4 3034.1 - 985427 - - - 3.4913 - 3.299 0.646 - 816.6 1 2 0 0.0065 16 0 0 0 1.04E+07 1.74E+07 - - - 6.7449 1 221125_WJC_METTL3_EV_vs_WT_F04.17731.17731.3 3.98E-07 16/56 R.REPFLLSGGDDGALK.L sp|Q9BQ67|GRWD1_HUMAN 1 1573.81 1.03 51284 17731 3 1573.813801 525.6106 Glutamate-rich WD repeat-containing protein 1 OS=Homo sapiens OX=9606 GN=GRWD1 PE=1 SV=1 4.56 3034.2 - 898329 - - - 2.4018 - 3.032 0.514 - 387.5 1 2 0 0.0038 15 0 0 0 1.24E+07 1.21E+07 - - - 7.1639 0.9999 221125_WJC_METTL3_EV_vs_WT_F04.17734.17734.4 5.89E-05 14/90 R.ELVLVVQVHNR[166.11]PEYLR[166.11].L sp|Q10469|MGAT2_HUMAN 1 1983.1169 1.1 51287 17734 4 1983.117569 496.7865 "Alpha-1,6-mannosyl-glycoprotein 2-beta-N-acetylglucosaminyltransferase OS=Homo sapiens OX=9606 GN=MGAT2 PE=1 SV=1" 6.86 3034.5 - 644571 - - - 0.3525 - 2.635 0.406 - 143 1 2 0 0.0007 16 0 0 0 2.20E+06 2.00E+06 - - - 3.1009 0.9992 221125_WJC_METTL3_EV_vs_WT_F04.17735.17735.3 0.00187 Sep-40 K.SKWEGNYLFPR.E "sp|Q9BVI4|NOC4L_HUMAN,tr|F5H303|F5H303_HUMAN" 2 1395.6935 0.79 51288 17735 3 1395.695466 466.2385 Nucleolar complex protein 4 homolog OS=Homo sapiens OX=9606 GN=NOC4L PE=1 SV=1 8.31 3034.6 - 515145 - - - 1.3835 - 1.814 0.422 - 130.4 1 2 1 0.0019 11 0 0 0 6.23E+06 7.90E+06 - - - 4.9362 0.9796 221125_WJC_METTL3_EV_vs_WT_F04.17741.17741.3 0.0449 Aug-32 K.RDEFEFLEK.A "sp|Q14258|TRI25_HUMAN,tr|A0A3B3IUA7|A0A3B3IUA7_HUMAN" 2 1211.5823 0.09 51294 17741 3 1211.58589 404.868 E3 ubiquitin\ISG15 ligase TRIM25 OS=Homo sapiens OX=9606 GN=TRIM25 PE=1 SV=2 4.41 3035.4 - 172270 - - - 3.0019 - 1.449 0.227 - 97.7 1 2 0 0.0036 9 0 0 0 7.76E+05 8.78E+06 - - - 2.1876 0.9998 221125_WJC_METTL3_EV_vs_WT_F04.17743.17743.3 9.05E-05 Dec-56 R.GALQNIIPASTGAAK.A "sp|P04406|G3P_HUMAN,tr|E7EUT5|E7EUT5_HUMAN" 2 1410.7831 1.06 51295 17743 3 1410.785184 471.2683 Glyceraldehyde-3-phosphate dehydrogenase OS=Homo sapiens OX=9606 GN=GAPDH PE=1 SV=3 8.75 3035.6 - 3.05E+06 - - - 1.4928 - 2.488 0.37 - 179.2 1 2 0 0.0021 15 0 0 0 1.26E+09 1.19E+09 - - - 5.0429 1 221125_WJC_METTL3_EV_vs_WT_F04.17744.17744.3 5.83E-06 14/56 R.GALQNIIPASTGAAK[136.11].A "sp|P04406|G3P_HUMAN,tr|E7EUT5|E7EUT5_HUMAN" 2 1418.7973 1.06 51296 17744 3 1418.799098 473.9397 Glyceraldehyde-3-phosphate dehydrogenase OS=Homo sapiens OX=9606 GN=GAPDH PE=1 SV=3 8.75 3035.7 - 1.70E+06 - - - 1.2828 - 2.817 0.462 - 265.9 1 2 0 0.0018 15 0 0 0 1.26E+09 1.19E+09 - - - 6.3928 0.9999 221125_WJC_METTL3_EV_vs_WT_F04.17747.17747.3 0.00131 14/56 R.R[166.11]EPFLLSGGDDGALK[136.11].L sp|Q9BQ67|GRWD1_HUMAN 1 1591.8325 1.03 51299 17747 3 1591.835408 531.6181 Glutamate-rich WD repeat-containing protein 1 OS=Homo sapiens OX=9606 GN=GRWD1 PE=1 SV=1 4.56 3035.9 - 2.01E+06 - - - 1.8325 - 2.736 0.454 - 235.8 1 2 0 0.0029 15 0 0 0 1.24E+07 1.21E+07 - - - 6.2272 0.9997 221125_WJC_METTL3_EV_vs_WT_F04.17749.17749.2 0.0593 13/24 K.TIEVLQLQDQGSK[136.11].M "sp|Q96GC5|RM48_HUMAN,tr|F5H702|F5H702_HUMAN" 2 1465.7868 1.09 51301 17749 2 1465.790405 733.9007 "39S ribosomal protein L48, mitochondrial OS=Homo sapiens OX=9606 GN=MRPL48 PE=1 SV=2" 4.37 3036 - 1.70E+06 - - - 2.4779 - 2.634 0.495 - 451 1 2 0 0.0036 13 0 0 0 1.17E+07 1.07E+07 - - - 5.1816 1 221125_WJC_METTL3_EV_vs_WT_F04.17750.17750.3 2.17E-07 15/44 K.APIQDIWYHEDR[166.11].L "sp|Q9Y3D9|RT23_HUMAN,tr|J3QLR8|J3QLR8_HUMAN" 2 1551.7346 1.01 51302 17750 3 1551.7383 518.2521 "28S ribosomal protein S23, mitochondrial OS=Homo sapiens OX=9606 GN=MRPS23 PE=1 SV=2" 4.54 3036.1 - 1.69E+06 - - - 2.4089 - 2.668 0.535 - 448.2 1 2 0 0.0037 12 0 0 0 1.25E+07 1.23E+07 - - - 7.2238 1 221125_WJC_METTL3_EV_vs_WT_F04.17752.17752.3 4.79E-06 13/56 K.C[160.03]VTTELYADSSQLSR.E "sp|Q6W2J9|BCOR_HUMAN,tr|H7BZ37|H7BZ37_HUMAN,tr|A1A564|A1A564_HUMAN,tr|H7C2V9|H7C2V9_HUMAN,tr|H7BYY2|H7BYY2_HUMAN,tr|H7C231|H7C231_HUMAN" 6 1728.7989 1.6 51304 17752 3 1728.799744 577.2736 BCL-6 corepressor OS=Homo sapiens OX=9606 GN=BCOR PE=1 SV=1 4.37 3036.3 - 1.05E+06 - - - 0.5084 - 2.721 0.488 - 157.9 1 2 0 0.0009 15 0 0 0 8.02E+06 5.00E+06 - - - 6.5924 0.9906 221125_WJC_METTL3_EV_vs_WT_F04.17754.17754.3 0.465 Nov-44 K.EK[136.11]PVDLQNFGLR[166.11].T sp|Q92922|SMRC1_HUMAN 1 1432.7793 1.65 51306 17754 3 1432.7797 478.6004 SWI\SNF complex subunit SMARCC1 OS=Homo sapiens OX=9606 GN=SMARCC1 PE=1 SV=3 6.17 3036.4 - 857358 - - - 0.2554 - 1.905 0.136 - 190.4 1 2 0 0.0004 12 0 0 0 3.77E+07 2.29E+07 - - - 1.8426 1 221125_WJC_METTL3_EV_vs_WT_F04.17757.17757.2 8.50E-06 14/30 K.EGVQGPLNVSLSEEGK[136.11].S sp|P12270|TPR_HUMAN 1 1649.8352 3.48 51309 17757 2 1649.836631 825.9249 Nucleoprotein TPR OS=Homo sapiens OX=9606 GN=TPR PE=1 SV=3 4.25 3036.8 - 682388 - - - 0.8795 - 3.221 0.579 - 743.5 1 2 0 0.0015 16 0 0 0 1.74E+07 5.01E+06 - - - 6.1928 1 221125_WJC_METTL3_EV_vs_WT_F04.17759.17759.2 3.91E-11 15/32 K.IISNASC[160.03]TTNC[160.03]LAPLAK.V "sp|P04406|G3P_HUMAN,tr|E7EUT5|E7EUT5_HUMAN" 2 1832.9125 -1 51311 17759 2 1833.899201 917.4635 Glyceraldehyde-3-phosphate dehydrogenase OS=Homo sapiens OX=9606 GN=GAPDH PE=1 SV=3 8.06 3037 - 546854 - - - 538.3487 - 3.042 0.698 - 571.7 1 2 0 0.9867 17 0 0 0 0.00E+00 0.00E+00 - - - 6.6218 0.9983 221125_WJC_METTL3_EV_vs_WT_F04.17762.17762.3 8.88E-10 15/96 A.AATGSYGAAAAYGAQPSATLAAPYR.T sp|Q96PK6|RBM14_HUMAN 1 2356.1448 999 51314 17762 3 2356.148718 786.3889 RNA-binding protein 14 OS=Homo sapiens OX=9606 GN=RBM14 PE=1 SV=2 8.54 3037.4 - 392920 - - - 1.6739 - 3.315 0.621 - 134.1 1 1 0 0.0039 25 0 0 0 2.90E+06 0.00E+00 - - - 8.2197 0.9947 221125_WJC_METTL3_EV_vs_WT_F04.17766.17766.3 0.000269 Sep-44 K.EKPVDLQNFGLR.T sp|Q92922|SMRC1_HUMAN 1 1414.7569 1.65 51317 17766 3 1414.763601 472.5929 SWI\SNF complex subunit SMARCC1 OS=Homo sapiens OX=9606 GN=SMARCC1 PE=1 SV=3 6.17 3037.8 - 3.29E+06 - - - 4.7619 - 1.877 0.337 - 163.2 1 2 0 0.0067 12 0 0 0 3.77E+07 2.29E+07 - - - 4.0407 1 221125_WJC_METTL3_EV_vs_WT_F04.17767.17767.3 6.55E-07 14/44 K.SWEEQMIEVGR[166.11]K[136.11].D sp|Q00059|TFAM_HUMAN 1 1508.7412 0.91 51318 17767 3 1508.743939 503.921 "Transcription factor A, mitochondrial OS=Homo sapiens OX=9606 GN=TFAM PE=1 SV=1" 4.78 3037.9 - 1.63E+06 - - - 1.7935 - 2.31 0.581 - 326.4 1 2 0 0.0027 12 0 0 0 7.91E+06 8.67E+06 - - - 7.3375 1 221125_WJC_METTL3_EV_vs_WT_F04.17768.17768.3 8.83E-09 15/60 R.QYTSPEEIDAQLQAEK[136.11].Q "sp|Q13442|HAP28_HUMAN,tr|F8WBW6|F8WBW6_HUMAN" 2 1856.8883 -1 51319 17768 3 1856.893665 619.9701 28 kDa heat- and acid-stable phosphoprotein OS=Homo sapiens OX=9606 GN=PDAP1 PE=1 SV=1 4 3037.9 - 1.53E+06 - - - 2.8688 - 2.668 0.6 - 399.3 1 2 0 0.0053 16 0 0 0 0.00E+00 0.00E+00 - - - 7.7459 0.9999 221125_WJC_METTL3_EV_vs_WT_F04.17769.17769.3 1.74E-07 Nov-56 K.C[160.03]VTTELYADSSQLSR[166.11].E "sp|Q6W2J9|BCOR_HUMAN,tr|H7BZ37|H7BZ37_HUMAN,tr|A1A564|A1A564_HUMAN,tr|H7C2V9|H7C2V9_HUMAN,tr|H7BYY2|H7BYY2_HUMAN,tr|H7C231|H7C231_HUMAN" 6 1738.8071 1.6 51320 17769 3 1738.810548 580.6097 BCL-6 corepressor OS=Homo sapiens OX=9606 GN=BCOR PE=1 SV=1 4.37 3038 - 1.49E+06 - - - 1.9628 - 2.541 0.466 - 115.9 1 2 0 0.0034 15 0 0 0 8.02E+06 5.00E+06 - - - 6.1679 1 221125_WJC_METTL3_EV_vs_WT_F04.17772.17772.2 5.93E-07 19/28 K.C[160.03]VTTELYADSSQLSR.E "sp|Q6W2J9|BCOR_HUMAN,tr|H7BZ37|H7BZ37_HUMAN,tr|A1A564|A1A564_HUMAN,tr|H7C2V9|H7C2V9_HUMAN,tr|H7BYY2|H7BYY2_HUMAN,tr|H7C231|H7C231_HUMAN" 6 1728.7989 1.49 51323 17772 2 1728.801013 865.4067 BCL-6 corepressor OS=Homo sapiens OX=9606 GN=BCOR PE=1 SV=1 4.37 3038.3 - 974898 - - - 1.2425 - 3.015 0.668 - 1202 1 2 0 0.0021 15 0 0 0 3.44E+06 2.31E+06 - - - 6.6874 0.9999 221125_WJC_METTL3_EV_vs_WT_F04.17774.17774.3 1.55E-05 14/60 R.QYTSPEEIDAQLQAEK.Q "sp|Q13442|HAP28_HUMAN,tr|F8WBW6|F8WBW6_HUMAN" 2 1848.8741 -1 51325 17774 3 1848.875162 617.2987 28 kDa heat- and acid-stable phosphoprotein OS=Homo sapiens OX=9606 GN=PDAP1 PE=1 SV=1 4 3038.6 - 808079 - - - 0.5539 - 2.397 0.446 - 328.3 1 2 0 0.001 16 0 0 0 0.00E+00 0.00E+00 - - - 5.7553 0.9997 221125_WJC_METTL3_EV_vs_WT_F04.17775.17775.3 8.77E-05 Nov-60 K.IQFVEHEELDAQELAK.R sp|Q86X52|CHSS1_HUMAN 1 1897.9422 1.15 51326 17775 3 1897.946787 633.6547 Chondroitin sulfate synthase 1 OS=Homo sapiens OX=9606 GN=CHSY1 PE=1 SV=3 4.25 3038.7 - 657977 - - - 2.439 - 2.357 0.38 - 169 1 2 0 0.0046 16 0 0 0 2.76E+06 2.41E+06 - - - 4.9753 0.9999 221125_WJC_METTL3_EV_vs_WT_F04.17776.17776.3 0.000187 14/48 K.QGEGVPDLVHVMR[166.11].T sp|P35813|PPM1A_HUMAN 1 1445.7325 1.27 51327 17776 3 1445.736443 482.9181 Protein phosphatase 1A OS=Homo sapiens OX=9606 GN=PPM1A PE=1 SV=1 5.32 3038.8 - 639051 - - - 2.7598 - 2.867 0.506 - 378.1 1 2 0 0.004 13 0 0 0 4.74E+06 3.74E+06 - - - 7.036 0.9998 221125_WJC_METTL3_EV_vs_WT_F04.17777.17777.3 1.96E-06 15/64 R.LDNVPHTPSSYIETLPK.A "sp|Q99733|NP1L4_HUMAN,tr|E9PP22|E9PP22_HUMAN,tr|A8MXH2|A8MXH2_HUMAN,tr|E9PKI2|E9PKI2_HUMAN,tr|C9J6D1|C9J6D1_HUMAN,tr|E9PJJ2|E9PJJ2_HUMAN,tr|E9PNW0|E9PNW0_HUMAN,tr|E9PS34|E9PS34_HUMAN,tr|E9PNJ7|E9PNJ7_HUMAN" 9 1909.9785 1.03 51328 17777 3 1909.985947 637.6668 Nucleosome assembly protein 1-like 4 OS=Homo sapiens OX=9606 GN=NAP1L4 PE=1 SV=1 5.32 3038.9 - 626832 - - - 3.8765 - 2.816 0.521 - 220.2 1 2 0 0.0074 17 0 0 0 5.31E+06 5.15E+06 - - - 6.9621 0.9968 221125_WJC_METTL3_EV_vs_WT_F04.17778.17778.3 0.088 Nov-56 R.YEAVGSVHQAWEAIR.A sp|Q9BV20|MTNA_HUMAN 1 1714.8427 1.09 51329 17778 3 1714.844913 572.6215 Methylthioribose-1-phosphate isomerase OS=Homo sapiens OX=9606 GN=MRI1 PE=1 SV=1 5.4 3039 - 617972 - - - 1.28 - 1.894 0.235 - 63.5 2 2 0 0.0022 15 0 0 0 5.37E+06 4.94E+06 - - - 2.6867 1 221125_WJC_METTL3_EV_vs_WT_F04.17781.17781.2 3.41E-09 16/28 K.C[160.03]VTTELYADSSQLSR[166.11].E "sp|Q6W2J9|BCOR_HUMAN,tr|H7BZ37|H7BZ37_HUMAN,tr|A1A564|A1A564_HUMAN,tr|H7C2V9|H7C2V9_HUMAN,tr|H7BYY2|H7BYY2_HUMAN,tr|H7C231|H7C231_HUMAN" 6 1738.8071 1.49 51332 17781 2 1738.809848 870.4108 BCL-6 corepressor OS=Homo sapiens OX=9606 GN=BCOR PE=1 SV=1 4.37 3039.3 - 548200 - - - 1.5603 - 2.792 0.69 - 697.3 1 2 0 0.0027 15 0 0 0 3.44E+06 2.31E+06 - - - 6.6608 1 221125_WJC_METTL3_EV_vs_WT_F04.17782.17782.2 2.01E-07 24-Dec K.AMQEQLENYDFTK[136.11].F sp|Q9H223|EHD4_HUMAN 1 1623.733 2.14 51333 17782 2 1623.734408 812.8738 EH domain-containing protein 4 OS=Homo sapiens OX=9606 GN=EHD4 PE=1 SV=1 4.14 3039.5 - 519940 - - - 0.853 - 2.719 0.656 - 648.6 1 2 0 0.0014 13 0 0 0 3.27E+06 1.53E+06 - - - 6.453 1 221125_WJC_METTL3_EV_vs_WT_F04.17786.17786.2 4.69E-05 15/28 K.TETISFGSVSPGGVK[136.11].L "sp|Q9Y2J2|E41L3_HUMAN,tr|J3QS83|J3QS83_HUMAN,tr|A0A0A0MRA8|A0A0A0MRA8_HUMAN,tr|A8K968|A8K968_HUMAN,tr|A0A0J9YY18|A0A0J9YY18_HUMAN,tr|A0A0A0MSA4|A0A0A0MSA4_HUMAN" 6 1472.7602 0.71 51336 17786 2 1472.763996 737.3874 Band 4.1-like protein 3 OS=Homo sapiens OX=9606 GN=EPB41L3 PE=1 SV=2 5.66 3039.9 - 304730 - - - 2.5612 - 2.915 0.569 - 860 1 2 0 0.0038 15 0 0 0 1.14E+06 1.61E+06 - - - 5.8728 1 221125_WJC_METTL3_EV_vs_WT_F04.17787.17787.3 5.28E-07 20/68 K.MVMIQDGPLPTGADKPLR.L sp|Q96I24|FUBP3_HUMAN 1 1938.0067 2.04 51337 17787 3 1938.010035 647.0095 Far upstream element-binding protein 3 OS=Homo sapiens OX=9606 GN=FUBP3 PE=1 SV=2 5.71 3040 - 1.39E+07 - - - 1.7265 - 3.665 0.626 - 468.6 1 2 0 0.0033 18 0 0 0 6.91E+07 3.39E+07 - - - 8.7526 0.9999 221125_WJC_METTL3_EV_vs_WT_F04.17794.17794.3 1.62E-05 13/52 R.GLHSQNFTQALLER.M "sp|Q9Y4W2|LAS1L_HUMAN,tr|A0A7I2V3R6|A0A7I2V3R6_HUMAN,tr|A0A7I2V3Q3|A0A7I2V3Q3_HUMAN,tr|A0A7I2V5R7|A0A7I2V5R7_HUMAN,tr|A0A7I2V653|A0A7I2V653_HUMAN,tr|A0A7I2V4E5|A0A7I2V4E5_HUMAN,tr|A0A7I2YQI7|A0A7I2YQI7_HUMAN" 7 1612.8322 1.08 51344 17794 3 1612.836788 538.618 Ribosomal biogenesis protein LAS1L OS=Homo sapiens OX=9606 GN=LAS1L PE=1 SV=2 6.75 3040.6 - 783824 - - - 2.8732 - 2.395 0.491 - 207.7 1 2 0 0.0046 14 0 0 0 4.43E+06 4.09E+06 - - - 6.3339 1 221125_WJC_METTL3_EV_vs_WT_F04.17795.17795.3 8.55E-05 Dec-48 R.FGDDLNHISC[160.03]VIK.E "sp|Q8IXM2|BAP18_HUMAN,tr|H0YIS7|H0YIS7_HUMAN,tr|F8W038|F8W038_HUMAN,tr|F8W1H0|F8W1H0_HUMAN" 4 1516.7344 1.67 51345 17795 3 1516.736204 506.5854 Chromatin complexes subunit BAP18 OS=Homo sapiens OX=9606 GN=BAP18 PE=1 SV=1 5.21 3040.7 - 727711 - - - 1.1802 - 2.546 0.474 - 75.5 1 2 0 0.0018 13 0 0 0 5.55E+06 3.32E+06 - - - 6.3579 1 221125_WJC_METTL3_EV_vs_WT_F04.17802.17802.2 8.16E-13 14/32 K.GEIGDATPFNDAVNVQK.L "sp|P30876|RPB2_HUMAN,tr|C9J4M6|C9J4M6_HUMAN,tr|C9J2Y9|C9J2Y9_HUMAN" 3 1773.8533 1.37 51352 17802 2 1773.854457 887.9339 DNA-directed RNA polymerase II subunit RPB2 OS=Homo sapiens OX=9606 GN=POLR2B PE=1 SV=1 4.03 3041.6 - 396986 - - - 0.628 - 3.052 0.7 - 475.8 1 2 0 0.0011 17 0 0 0 1.89E+06 1.38E+06 - - - 6.9541 0.9995 221125_WJC_METTL3_EV_vs_WT_F04.17806.17806.2 2.35E-06 20-Aug R.EAQNDLEQVLR.Q sp|Q15075|EEA1_HUMAN 1 1313.6575 -1 51355 17806 2 1313.660208 657.836 Early endosome antigen 1 OS=Homo sapiens OX=9606 GN=EEA1 PE=1 SV=2 4.14 3042.2 - 212872 - - - 2.0287 - 1.705 0.493 - 142.9 1 2 0 0.0027 11 0 0 0 0.00E+00 0.00E+00 - - - 4.1249 0.9999 221125_WJC_METTL3_EV_vs_WT_F04.17809.17809.3 0.00012 13/44 R.LNHLVDSLQQLR[166.11].L "sp|P35658|NU214_HUMAN,tr|A0A0A0MSW3|A0A0A0MSW3_HUMAN,tr|A0A494C1F2|A0A494C1F2_HUMAN" 3 1444.8026 2.39 51358 17809 3 1444.804925 482.6081 Nuclear pore complex protein Nup214 OS=Homo sapiens OX=9606 GN=NUP214 PE=1 SV=2 6.74 3042.4 - 1.40E+06 - - - 1.6217 - 2.369 0.393 - 317.6 1 2 0 0.0023 12 0 0 0 1.79E+07 7.51E+06 - - - 5.3115 1 221125_WJC_METTL3_EV_vs_WT_F04.17811.17811.3 8.80E-08 15/48 R.FGDDLNHISC[160.03]VIK[136.11].E "sp|Q8IXM2|BAP18_HUMAN,tr|H0YIS7|H0YIS7_HUMAN,tr|F8W038|F8W038_HUMAN,tr|F8W1H0|F8W1H0_HUMAN" 4 1524.7486 2.1 51360 17811 3 1524.752279 509.2568 Chromatin complexes subunit BAP18 OS=Homo sapiens OX=9606 GN=BAP18 PE=1 SV=1 5.21 3042.7 - 1.02E+06 - - - 2.4037 - 2.466 0.595 - 135.5 1 2 0 0.0037 13 0 0 0 6.96E+06 3.32E+06 - - - 7.6198 0.9903 221125_WJC_METTL3_EV_vs_WT_F04.17812.17812.3 3.88E-06 15/48 Q.SIVPALEIANAHR.K "sp|P10809|CH60_HUMAN,tr|A0A7I2V2X6|A0A7I2V2X6_HUMAN,tr|A0A7I2YQK6|A0A7I2YQK6_HUMAN,tr|A0A7I2V599|A0A7I2V599_HUMAN,tr|A0A7I2YQ71|A0A7I2YQ71_HUMAN,tr|A0A7I2V5M1|A0A7I2V5M1_HUMAN,tr|A0A7I2V5K3|A0A7I2V5K3_HUMAN,tr|A0A7I2V369|A0A7I2V369_HUMAN" 8 1389.7728 1.39 51361 17812 3 1389.775235 464.2649 "60 kDa heat shock protein, mitochondrial OS=Homo sapiens OX=9606 GN=HSPD1 PE=1 SV=2" 6.47 3042.8 - 990313 - - - 1.7175 - 2.867 0.391 - 212.3 1 1 0 0.0024 13 0 0 0 1.42E+07 1.03E+07 - - - 5.7543 0.9905 221125_WJC_METTL3_EV_vs_WT_F04.17814.17814.3 1.15E-07 15/48 Q.SIVPALEIANAHR[166.11].K "sp|P10809|CH60_HUMAN,tr|A0A7I2V2X6|A0A7I2V2X6_HUMAN,tr|A0A7I2YQK6|A0A7I2YQK6_HUMAN,tr|A0A7I2V599|A0A7I2V599_HUMAN,tr|A0A7I2YQ71|A0A7I2YQ71_HUMAN,tr|A0A7I2V5M1|A0A7I2V5M1_HUMAN,tr|A0A7I2V5K3|A0A7I2V5K3_HUMAN,tr|A0A7I2V369|A0A7I2V369_HUMAN" 8 1399.7811 1.39 51363 17814 3 1399.785891 467.601 "60 kDa heat shock protein, mitochondrial OS=Homo sapiens OX=9606 GN=HSPD1 PE=1 SV=2" 6.47 3043 - 745722 - - - 3.4098 - 2.948 0.518 - 279.7 1 1 0 0.0048 13 0 0 0 1.42E+07 1.03E+07 - - - 7.2451 0.9999 221125_WJC_METTL3_EV_vs_WT_F04.17817.17817.3 0.00146 Dec-36 R.RDAETWFLSK.T "sp|P08779|K1C16_HUMAN,tr|K7ENW6|K7ENW6_HUMAN" 2 1251.6248 59.32 51366 17817 3 1251.626404 418.2155 "Keratin, type I cytoskeletal 16 OS=Homo sapiens OX=9606 GN=KRT16 PE=1 SV=4" 6.07 3043.4 - 559952 - - - 1.2919 - 2.412 0.413 - 288.6 1 2 0 0.0016 10 0 0 0 5.08E+06 8.56E+04 - - - 5.7154 1 221125_WJC_METTL3_EV_vs_WT_F04.17818.17818.3 9.66E-07 16/64 R.LLTTILHSDGDLTEQGK[136.11].L sp|Q9NTI5|PDS5B_HUMAN 1 1847.972 0.53 51367 17818 3 1847.975875 616.9979 Sister chromatid cohesion protein PDS5 homolog B OS=Homo sapiens OX=9606 GN=PDS5B PE=1 SV=1 4.54 3043.5 - 557095 - - - 2.0926 - 2.989 0.559 - 221.1 1 2 0 0.0039 17 0 0 0 1.07E+06 2.00E+06 - - - 7.5374 1 221125_WJC_METTL3_EV_vs_WT_F04.17819.17819.3 2.69E-07 14/52 R.LSDGELLFEC[160.03]AGHK[136.11].D "sp|Q13685|AAMP_HUMAN,tr|C9JG97|C9JG97_HUMAN,tr|C9JEH3|C9JEH3_HUMAN,tr|C9JTS3|C9JTS3_HUMAN" 4 1582.7541 0.81 51368 17819 3 1582.757944 528.592 Angio-associated migratory cell protein OS=Homo sapiens OX=9606 GN=AAMP PE=1 SV=2 4.65 3043.6 - 538487 - - - 2.4331 - 2.649 0.567 - 244.9 1 2 0 0.0039 14 0 0 0 1.62E+06 1.99E+06 - - - 7.4493 0.998 221125_WJC_METTL3_EV_vs_WT_F04.17821.17821.3 0.000484 Oct-60 K.LAEQAERYDEMVESMK.K "sp|P62258|1433E_HUMAN,tr|B4DJF2|B4DJF2_HUMAN,tr|I3L3T1|I3L3T1_HUMAN" 3 1927.8656 0.57 51370 17821 3 1927.859544 643.6291 14-3-3 protein epsilon OS=Homo sapiens OX=9606 GN=YWHAE PE=1 SV=1 4.25 3043.9 - 496631 - - - -3.1226 - 2.17 0.414 - 108.4 1 2 1 -0.006 16 0 0 0 2.66E+06 4.64E+06 - - - 5.1419 1 221125_WJC_METTL3_EV_vs_WT_F04.17823.17823.2 5.86E-10 16/38 R.QLEVYTSGGDPESVAGEYGR[166.11].H "sp|Q9Y262|EIF3L_HUMAN,tr|B0QY89|B0QY89_HUMAN,tr|B0QY90|B0QY90_HUMAN" 3 2122.9683 1.15 51372 17823 2 2122.969754 1062.4914 Eukaryotic translation initiation factor 3 subunit L OS=Homo sapiens OX=9606 GN=EIF3L PE=1 SV=1 4 3044.1 - 421629 - - - 0.7023 - 3.291 0.627 - 476.3 1 2 0 0.0015 20 0 0 0 1.95E+06 1.70E+06 - - - 6.6002 1 221125_WJC_METTL3_EV_vs_WT_F04.17824.17824.2 8.24E-09 17/38 R.QLEVYTSGGDPESVAGEYGR.H "sp|Q9Y262|EIF3L_HUMAN,tr|B0QY89|B0QY89_HUMAN,tr|B0QY90|B0QY90_HUMAN" 3 2112.96 1.15 51373 17824 2 2112.962253 1057.4873 Eukaryotic translation initiation factor 3 subunit L OS=Homo sapiens OX=9606 GN=EIF3L PE=1 SV=1 4 3044.3 - 393970 - - - 1.0696 - 3.704 0.7 - 479.1 1 2 0 0.0023 20 0 0 0 1.95E+06 1.70E+06 - - - 7.4297 0.9318 221125_WJC_METTL3_EV_vs_WT_F04.17825.17825.4 0.000146 Oct-72 K.LKDLFDYSPPLHK.N "sp|Q9NYF8|BCLF1_HUMAN,tr|E9PKI6|E9PKI6_HUMAN,tr|A0A1W2PQ43|A0A1W2PQ43_HUMAN,tr|E9PK91|E9PK91_HUMAN,tr|E9PK09|E9PK09_HUMAN,tr|E9PQN2|E9PQN2_HUMAN" 6 1571.8348 2.3 51374 17825 4 1571.839056 393.966 Bcl-2-associated transcription factor 1 OS=Homo sapiens OX=9606 GN=BCLAF1 PE=1 SV=2 6.75 3044.4 - 358821 - - - 2.7204 - 1.94 0.209 - 87.3 1 2 1 0.0043 13 0 0 0 8.55E+06 3.71E+06 - - - 1.2897 1 221125_WJC_METTL3_EV_vs_WT_F04.17831.17831.3 3.00E-09 20/76 R.LPLQLDDAVRPEAEGEEEGR.A "sp|P14868|SYDC_HUMAN,tr|C9J7S3|C9J7S3_HUMAN,tr|C9JLC1|C9JLC1_HUMAN" 3 2222.0815 1.43 51379 17831 3 2222.085121 741.7011 "Aspartate--tRNA ligase, cytoplasmic OS=Homo sapiens OX=9606 GN=DARS1 PE=1 SV=2" 4 3044.9 - 1.68E+06 - - - 1.6273 - 3.451 0.682 - 525.8 1 2 0 0.0036 20 0 0 0 1.97E+07 1.38E+07 - - - 9.1477 0.9885 221125_WJC_METTL3_EV_vs_WT_F04.17832.17832.2 4.27E-07 13/28 K.QYNGVPLDGRPMNIQ.L "sp|Q86V81|THOC4_HUMAN,tr|E9PB61|E9PB61_HUMAN" 2 1700.8304 1.63 51380 17832 2 1700.83314 851.4225 THO complex subunit 4 OS=Homo sapiens OX=9606 GN=ALYREF PE=1 SV=3 5.84 3045 - 1.08E+06 - - - 1.588 - 2.218 0.553 - 296.4 1 1 0 0.0027 15 0 0 0 1.68E+07 1.03E+07 - - - 5.0831 1 221125_WJC_METTL3_EV_vs_WT_F04.17833.17833.2 9.84E-09 15/24 R.AQQMVEILSDENR.N "sp|Q4VCS5|AMOT_HUMAN,tr|A6NP16|A6NP16_HUMAN,tr|E7ERM3|E7ERM3_HUMAN" 3 1531.7301 1.56 51381 17833 2 1531.732878 766.8723 Angiomotin OS=Homo sapiens OX=9606 GN=AMOT PE=1 SV=1 4.14 3045.1 - 762324 - - - 1.8424 - 3.062 0.681 - 1195.2 1 2 0 0.0028 13 0 0 0 7.57E+06 4.86E+06 - - - 6.9421 0.9995 221125_WJC_METTL3_EV_vs_WT_F04.17834.17834.3 0.00449 Nov-52 K.TVVLHIDGLDDTSR.R "sp|Q9NVT9|ARMC1_HUMAN,tr|E5RJ86|E5RJ86_HUMAN" 2 1539.7893 2.98 51382 17834 3 1539.794158 514.2704 Armadillo repeat-containing protein 1 OS=Homo sapiens OX=9606 GN=ARMC1 PE=1 SV=1 4.41 3045.2 - 757893 - - - 3.1641 - 2.007 0.411 - 123.2 1 2 0 0.0049 14 0 0 0 4.93E+06 1.66E+06 - - - 4.9722 0.9999 221125_WJC_METTL3_EV_vs_WT_F04.17836.17836.3 2.75E-05 Dec-40 R.ISDEDWDIIHR[166.11].V "sp|P51659|DHB4_HUMAN,tr|A0A2R8YD50|A0A2R8YD50_HUMAN,tr|E7ER27|E7ER27_HUMAN,tr|A0A2R8YF45|A0A2R8YF45_HUMAN,tr|E7EPL9|E7EPL9_HUMAN,tr|A0A804HKU2|A0A804HKU2_HUMAN,tr|A0A2R8YDT8|A0A2R8YDT8_HUMAN,tr|A0A804HK65|A0A804HK65_HUMAN" 8 1407.6658 0.76 51384 17836 3 1407.66791 470.2292 Peroxisomal multifunctional enzyme type 2 OS=Homo sapiens OX=9606 GN=HSD17B4 PE=1 SV=3 4.22 3045.4 - 449007 - - - 1.4897 - 2.325 0.477 - 301.1 1 2 0 0.0021 11 0 0 0 1.00E+07 1.31E+07 - - - 6.2544 0.9999 221125_WJC_METTL3_EV_vs_WT_F04.17839.17839.3 5.72E-05 17/64 R.LLTTILHSDGDLTEQGK.L sp|Q9NTI5|PDS5B_HUMAN 1 1839.9578 0.53 51387 17839 3 1839.962591 614.3265 Sister chromatid cohesion protein PDS5 homolog B OS=Homo sapiens OX=9606 GN=PDS5B PE=1 SV=1 4.54 3045.9 - 353100 - - - 2.5995 - 2.614 0.451 - 298.1 1 2 0 0.0048 17 0 0 0 1.07E+06 2.00E+06 - - - 5.9944 0.999 221125_WJC_METTL3_EV_vs_WT_F04.17840.17840.3 0.00571 13/52 K.AVHLQEELIAINSK.K sp|O75665|OFD1_HUMAN 1 1563.8621 4.87 51388 17840 3 1563.865362 522.2946 Oral-facial-digital syndrome 1 protein OS=Homo sapiens OX=9606 GN=OFD1 PE=1 SV=1 5.4 3046 - 307454 - - - 2.1134 - 2.189 0.29 - 174.8 1 2 0 0.0033 14 0 0 0 7.37E+05 1.51E+05 - - - 3.8543 0.9988 221125_WJC_METTL3_EV_vs_WT_F04.17842.17842.2 1.53E-07 24-Dec K.ENVVQSVTSVAEK.T sp|O76070|SYUG_HUMAN 1 1388.7147 3.74 51390 17842 2 1388.719886 695.3646 Gamma-synuclein OS=Homo sapiens OX=9606 GN=SNCG PE=1 SV=2 4.53 3046.2 - 223697 - - - 3.7171 - 2.509 0.405 - 559.5 1 2 0 0.0052 13 0 0 0 1.07E+07 2.86E+06 - - - 4.3916 1 221125_WJC_METTL3_EV_vs_WT_F04.17845.17845.2 2.87E-06 13/30 R.SLETENSALQLQVTER[166.11].E "sp|P20700|LMNB1_HUMAN,tr|A0A0D9SFY5|A0A0D9SFY5_HUMAN,tr|E9PBF6|E9PBF6_HUMAN,tr|A0A0D9SFE5|A0A0D9SFE5_HUMAN" 4 1826.9249 1.13 51393 17845 2 1826.925934 914.4697 Lamin-B1 OS=Homo sapiens OX=9606 GN=LMNB1 PE=1 SV=2 4.25 3046.6 - 180706 - - - 0.5435 - 3.104 0.566 - 628.3 1 2 0 0.001 16 0 0 0 2.02E+06 1.78E+06 - - - 6.0059 0.9998 221125_WJC_METTL3_EV_vs_WT_F04.17848.17848.2 0.000185 13/22 R.LNHLVDSLQQLR.L "sp|P35658|NU214_HUMAN,tr|A0A0A0MSW3|A0A0A0MSW3_HUMAN,tr|A0A494C1F2|A0A494C1F2_HUMAN" 3 1434.7943 13.3 51395 17848 2 1434.794707 718.4044 Nuclear pore complex protein Nup214 OS=Homo sapiens OX=9606 GN=NUP214 PE=1 SV=2 6.74 3047.1 - 579374 - - - 0.2753 - 2.154 0.425 - 697.7 1 2 0 0.0004 12 0 0 0 2.86E+06 2.15E+05 - - - 4.1989 0.9974 221125_WJC_METTL3_EV_vs_WT_F04.17849.17849.3 0.0457 Jul-44 R.DLKPANVFLDGK.Q "sp|P51955|NEK2_HUMAN,tr|F6U4U2|F6U4U2_HUMAN" 2 1315.7136 -1 51396 17849 3 1315.716236 439.5785 Serine\threonine-protein kinase Nek2 OS=Homo sapiens OX=9606 GN=NEK2 PE=1 SV=1 5.96 3047.2 - 86547.4 - - - 2.002 - 1.455 0.317 - 53.8 1 2 0 0.0026 12 0 0 0 0.00E+00 0.00E+00 - - - 3.113 1 221125_WJC_METTL3_EV_vs_WT_F04.17851.17851.3 1.42E-07 16/48 R.GYFEYIEENK[136.11]YSR[166.11].A "sp|Q00839|HNRPU_HUMAN,tr|Q5RI18|Q5RI18_HUMAN,tr|A0A1W2PP35|A0A1W2PP35_HUMAN,tr|A0A1W2PPS1|A0A1W2PPS1_HUMAN,tr|A0A1W2PRI6|A0A1W2PRI6_HUMAN" 5 1714.7958 0.95 51398 17851 3 1714.794662 572.6059 Heterogeneous nuclear ribonucleoprotein U OS=Homo sapiens OX=9606 GN=HNRNPU PE=1 SV=6 4.79 3047.3 - 3.46E+06 - - - -0.6473 - 2.93 0.602 - 302.6 1 2 1 -0.0011 13 0 0 0 1.34E+09 1.42E+09 - - - 8.166 1 221125_WJC_METTL3_EV_vs_WT_F04.17852.17852.3 3.45E-10 16/60 K.YFSTTEDYDHEITGLR.V "sp|Q96DA0|ZG16B_HUMAN,tr|I3L1H9|I3L1H9_HUMAN,tr|A0A0C4DGN4|A0A0C4DGN4_HUMAN,tr|I3L3X0|I3L3X0_HUMAN" 4 1945.8694 999 51399 17852 3 1945.872625 649.6304 Zymogen granule protein 16 homolog B OS=Homo sapiens OX=9606 GN=ZG16B PE=1 SV=3 4.31 3047.4 - 2.91E+06 - - - 1.664 - 3.444 0.676 - 186.7 1 2 0 0.0032 16 0 0 0 1.32E+07 0.00E+00 - - - 9.2489 0.9999 221125_WJC_METTL3_EV_vs_WT_F04.17853.17853.3 1.96E-06 17/48 R.GYFEYIEENKYSR.A "sp|Q00839|HNRPU_HUMAN,tr|Q5RI18|Q5RI18_HUMAN,tr|A0A1W2PP35|A0A1W2PP35_HUMAN,tr|A0A1W2PPS1|A0A1W2PPS1_HUMAN,tr|A0A1W2PRI6|A0A1W2PRI6_HUMAN" 5 1696.7733 0.95 51400 17853 3 1696.776342 566.5984 Heterogeneous nuclear ribonucleoprotein U OS=Homo sapiens OX=9606 GN=HNRNPU PE=1 SV=6 4.79 3047.4 - 2.45E+06 - - - 1.7916 - 2.914 0.576 - 358.7 1 2 1 0.003 13 0 0 0 1.34E+09 1.42E+09 - - - 7.8608 1 221125_WJC_METTL3_EV_vs_WT_F04.17854.17854.2 5.30E-12 18/30 R.QSGEAFVELGSEDDVK[136.11].M "sp|P52597|HNRPF_HUMAN,tr|A0A1B0GW42|A0A1B0GW42_HUMAN" 2 1716.7934 0.46 51401 17854 2 1716.792401 859.404 Heterogeneous nuclear ribonucleoprotein F OS=Homo sapiens OX=9606 GN=HNRNPF PE=1 SV=3 3.83 3047.5 - 2.39E+06 - - - -0.5673 - 3.306 0.69 - 1182.5 1 2 0 -0.001 16 0 0 0 8.48E+07 1.86E+08 - - - 7.0768 1 221125_WJC_METTL3_EV_vs_WT_F04.17855.17855.3 3.20E-09 22/76 R.LPLQLDDAVR[166.11]PEAEGEEEGR[166.11].A "sp|P14868|SYDC_HUMAN,tr|C9J7S3|C9J7S3_HUMAN,tr|C9JLC1|C9JLC1_HUMAN" 3 2242.098 1.4 51402 17855 3 2242.100314 748.3733 "Aspartate--tRNA ligase, cytoplasmic OS=Homo sapiens OX=9606 GN=DARS1 PE=1 SV=2" 4 3047.6 - 2.22E+06 - - - 1.012 - 3.605 0.644 - 624.1 1 2 0 0.0023 20 0 0 0 1.94E+07 1.38E+07 - - - 8.8303 1 221125_WJC_METTL3_EV_vs_WT_F04.17857.17857.3 2.16E-09 20/72 R.QVSASELHTSGILGPETLR.D "sp|P58107|EPIPL_HUMAN,sp|P58107|EPIPL_HUMAN,sp|P58107|EPIPL_HUMAN,sp|P58107|EPIPL_HUMAN,sp|P58107|EPIPL_HUMAN,tr|A0A075B730|A0A075B730_HUMAN,tr|A0A075B730|A0A075B730_HUMAN,tr|A0A075B730|A0A075B730_HUMAN,tr|A0A075B730|A0A075B730_HUMAN,tr|A0A075B730|A0A075B730_HUMAN" 10 1994.0433 0.56 51404 17857 3 1994.045278 665.6884 Epiplakin OS=Homo sapiens OX=9606 GN=EPPK1 PE=1 SV=3 5.4 3047.8 - 1.25E+06 - - - 1.0075 - 3.458 0.479 - 516.1 1 2 0 0.002 19 0 0 0 5.64E+07 1.01E+08 - - - 6.928 0.9997 221125_WJC_METTL3_EV_vs_WT_F04.17858.17858.3 0.00135 13/36 K.KADEVLEILK.T "sp|O75643|U520_HUMAN,tr|A0A494C1A5|A0A494C1A5_HUMAN" 2 1156.6703 1.89 51405 17858 3 1156.670942 386.5641 U5 small nuclear ribonucleoprotein 200 kDa helicase OS=Homo sapiens OX=9606 GN=SNRNP200 PE=1 SV=2 4.68 3047.9 - 1.20E+06 - - - 0.5205 - 2.511 0.261 - 278.1 1 2 0 0.0006 10 0 0 0 2.80E+07 1.48E+07 - - - 4.1385 0.9989 221125_WJC_METTL3_EV_vs_WT_F04.17862.17862.3 0.0696 Dec-36 K.K[136.11]ADEVLEILK[136.11].T "sp|O75643|U520_HUMAN,tr|A0A494C1A5|A0A494C1A5_HUMAN" 2 1172.6987 1.89 51409 17862 3 1172.699185 391.9069 U5 small nuclear ribonucleoprotein 200 kDa helicase OS=Homo sapiens OX=9606 GN=SNRNP200 PE=1 SV=2 4.68 3048.4 - 772584 - - - 0.3795 - 2.308 0.2 - 234 1 2 0 0.0004 10 0 0 0 2.80E+07 1.48E+07 - - - 3.2123 0.9996 221125_WJC_METTL3_EV_vs_WT_F04.17863.17863.3 0.00223 16/72 K.EIIIEERPGQELTDVNGVR.L sp|Q9BV20|MTNA_HUMAN 1 2166.1281 3.7 51410 17863 3 2166.122006 723.05 Methylthioribose-1-phosphate isomerase OS=Homo sapiens OX=9606 GN=MRI1 PE=1 SV=1 4.25 3048.5 - 771904 - - - -2.7953 - 2.521 0.381 - 271.5 1 2 0 -0.0061 19 0 0 0 3.32E+06 8.97E+05 - - - 5.0578 1 221125_WJC_METTL3_EV_vs_WT_F04.17864.17864.2 1.23E-08 14/24 R.AQQMVEILSDENR[166.11].N "sp|Q4VCS5|AMOT_HUMAN,tr|A6NP16|A6NP16_HUMAN,tr|E7ERM3|E7ERM3_HUMAN" 3 1541.7383 1.56 51411 17864 2 1541.739623 771.8764 Angiomotin OS=Homo sapiens OX=9606 GN=AMOT PE=1 SV=1 4.14 3048.7 - 674818 - - - 0.8413 - 2.96 0.594 - 1036.8 1 2 0 0.0013 13 0 0 0 7.57E+06 4.86E+06 - - - 6.213 0.9992 221125_WJC_METTL3_EV_vs_WT_F04.17866.17866.3 0.00458 Nov-64 R.FEPSSQMIEVQEGQNLK.L "sp|Q15155|NOMO1_HUMAN,sp|Q5JPE7|NOMO2_HUMAN,sp|P69849|NOMO3_HUMAN,tr|A0A7I2V3P4|A0A7I2V3P4_HUMAN,tr|A0A7I2V6B0|A0A7I2V6B0_HUMAN,tr|A0A7I2V4T6|A0A7I2V4T6_HUMAN,tr|A0A0G2JP90|A0A0G2JP90_HUMAN,tr|A0A087X117|A0A087X117_HUMAN,tr|A0A0G2JN29|A0A0G2JN29_HUMAN,tr|A0A7I2V2Z5|A0A7I2V2Z5_HUMAN,tr|A0A087WW46|A0A087WW46_HUMAN,tr|J3KN36|J3KN36_HUMAN" 12 1962.9357 2.56 51413 17866 3 1962.942558 655.3192 Nodal modulator 1 OS=Homo sapiens OX=9606 GN=NOMO1 PE=1 SV=5 4.25 3048.9 - 596156 - - - 3.4978 - 2.007 0.41 - 84.7 1 2 0 0.0069 17 0 0 0 5.73E+06 2.24E+06 - - - 4.8691 0.9999 221125_WJC_METTL3_EV_vs_WT_F04.17867.17867.3 4.82E-06 13/48 R.DLHVSTGEFTDLK.Q sp|O43264|ZW10_HUMAN 1 1460.7147 1.13 51414 17867 3 1460.717162 487.9122 Centromere\kinetochore protein zw10 homolog OS=Homo sapiens OX=9606 GN=ZW10 PE=1 SV=3 4.54 3049.1 - 539799 - - - 1.669 - 2.248 0.458 - 227.1 1 2 0 0.0024 13 0 0 0 3.18E+06 2.80E+06 - - - 5.8418 1 221125_WJC_METTL3_EV_vs_WT_F04.17871.17871.2 3.14E-10 18/30 R.QSGEAFVELGSEDDVK.M "sp|P52597|HNRPF_HUMAN,tr|A0A1B0GW42|A0A1B0GW42_HUMAN" 2 1708.7792 0.46 51417 17871 2 1708.78011 855.3969 Heterogeneous nuclear ribonucleoprotein F OS=Homo sapiens OX=9606 GN=HNRNPF PE=1 SV=3 3.83 3049.5 - 5.64E+06 - - - 0.5472 - 3.474 0.696 - 1258.9 1 2 0 0.0009 16 0 0 0 8.48E+07 1.86E+08 - - - 7.243 0.9999 221125_WJC_METTL3_EV_vs_WT_F04.17872.17872.2 0.00104 22-Nov K.LNISFPATGC[160.03]QK[136.11].L "sp|P62753|RS6_HUMAN,tr|A2A3R7|A2A3R7_HUMAN" 2 1342.6795 0.76 51418 17872 2 1342.680289 672.347 40S ribosomal protein S6 OS=Homo sapiens OX=9606 GN=RPS6 PE=1 SV=1 8.22 3049.5 - 3.39E+06 - - - 0.6085 - 2.428 0.534 - 368 1 2 0 0.0008 12 0 0 0 1.03E+08 1.36E+08 - - - 5.3189 1 221125_WJC_METTL3_EV_vs_WT_F04.17873.17873.2 1.88E-08 16/30 K.YGGISTASVDFEQPTR.D sp|P98175|RBM10_HUMAN 1 1726.8162 3.57 51419 17873 2 1726.816779 864.4154 RNA-binding protein 10 OS=Homo sapiens OX=9606 GN=RBM10 PE=1 SV=3 4.37 3049.6 - 1.69E+06 - - - 0.3185 - 2.95 0.673 - 899.3 1 2 0 0.0006 16 0 0 0 3.47E+07 9.71E+06 - - - 6.6713 0.9999 221125_WJC_METTL3_EV_vs_WT_F04.17875.17875.3 0.0014 Dec-40 R.ISDEDWDIIHR.V "sp|P51659|DHB4_HUMAN,tr|A0A2R8YD50|A0A2R8YD50_HUMAN,tr|E7ER27|E7ER27_HUMAN,tr|A0A2R8YF45|A0A2R8YF45_HUMAN,tr|E7EPL9|E7EPL9_HUMAN,tr|A0A804HKU2|A0A804HKU2_HUMAN,tr|A0A2R8YDT8|A0A2R8YDT8_HUMAN,tr|A0A804HK65|A0A804HK65_HUMAN" 8 1397.6575 0.76 51421 17875 3 1397.657699 466.8931 Peroxisomal multifunctional enzyme type 2 OS=Homo sapiens OX=9606 GN=HSD17B4 PE=1 SV=3 4.22 3049.7 - 1.55E+06 - - - 0.1116 - 2.251 0.427 - 253.7 1 2 0 0.0002 11 0 0 0 1.00E+07 1.31E+07 - - - 5.6056 1 221125_WJC_METTL3_EV_vs_WT_F04.17879.17879.2 0.00041 14/26 D.APATQDGVESLLQK[136.11].F "sp|Q86U44|MTA70_HUMAN,tr|B4E349|B4E349_HUMAN,tr|F5H6D8|F5H6D8_HUMAN,tr|H0YFV6|H0YFV6_HUMAN,tr|B4DTN4|B4DTN4_HUMAN" 5 1463.7711 0.02 51425 17879 2 1463.773798 732.8928 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 4.37 3050.2 - 492821 - - - 1.8275 - 3.172 0.528 - 634.3 1 1 0 0.0027 14 0 0 0 5.20E+05 3.09E+07 - - - 5.8368 1 221125_WJC_METTL3_EV_vs_WT_F04.17880.17880.3 1.08E-07 18/56 K.SPAPPLLHVAALGQK[136.11].Q "sp|Q8N163|CCAR2_HUMAN,tr|H0YC69|H0YC69_HUMAN,tr|E5RGU7|E5RGU7_HUMAN,tr|E5RFJ3|E5RFJ3_HUMAN,tr|H0YC58|H0YC58_HUMAN" 5 1505.8809 1.11 51426 17880 3 1505.880777 502.9676 Cell cycle and apoptosis regulator protein 2 OS=Homo sapiens OX=9606 GN=CCAR2 PE=1 SV=2 8.49 3050.4 - 446300 - - - -0.1136 - 3.095 0.536 - 400.8 1 2 0 -0.0002 15 0 0 0 1.92E+07 1.74E+07 - - - 7.4639 1 221125_WJC_METTL3_EV_vs_WT_F04.17882.17882.2 2.67E-05 13/30 R.SLETENSALQLQVTER.E "sp|P20700|LMNB1_HUMAN,tr|A0A0D9SFY5|A0A0D9SFY5_HUMAN,tr|E9PBF6|E9PBF6_HUMAN,tr|A0A0D9SFE5|A0A0D9SFE5_HUMAN" 4 1816.9167 1.13 51428 17882 2 1816.919968 909.4656 Lamin-B1 OS=Homo sapiens OX=9606 GN=LMNB1 PE=1 SV=2 4.25 3050.6 - 369448 - - - 1.8146 - 3.137 0.571 - 677.4 1 2 0 0.0033 16 0 0 0 2.02E+06 1.78E+06 - - - 6.0681 1 221125_WJC_METTL3_EV_vs_WT_F04.17883.17883.2 1.30E-09 13/32 R.FEPSSQMIEVQEGQNLK.L "sp|Q15155|NOMO1_HUMAN,sp|Q5JPE7|NOMO2_HUMAN,sp|P69849|NOMO3_HUMAN,tr|A0A7I2V3P4|A0A7I2V3P4_HUMAN,tr|A0A7I2V6B0|A0A7I2V6B0_HUMAN,tr|A0A7I2V4T6|A0A7I2V4T6_HUMAN,tr|A0A0G2JP90|A0A0G2JP90_HUMAN,tr|A0A087X117|A0A087X117_HUMAN,tr|A0A0G2JN29|A0A0G2JN29_HUMAN,tr|A0A7I2V2Z5|A0A7I2V2Z5_HUMAN,tr|A0A087WW46|A0A087WW46_HUMAN,tr|J3KN36|J3KN36_HUMAN" 12 1962.9357 2.77 51429 17883 2 1962.938369 982.4751 Nodal modulator 1 OS=Homo sapiens OX=9606 GN=NOMO1 PE=1 SV=5 4.25 3050.8 - 282893 - - - 1.3638 - 2.873 0.642 - 476.4 1 2 0 0.0027 17 0 0 0 2.69E+06 9.74E+05 - - - 6.3766 1 221125_WJC_METTL3_EV_vs_WT_F04.17886.17886.2 3.12E-09 15/32 L.GLPVGAVINC[160.03]ADNTGAK.N "sp|P62829|RL23_HUMAN,tr|J3KT29|J3KT29_HUMAN,tr|B9ZVP7|B9ZVP7_HUMAN,tr|C9JD32|C9JD32_HUMAN" 4 1655.8301 0.7 51432 17886 2 1655.830185 828.9223 60S ribosomal protein L23 OS=Homo sapiens OX=9606 GN=RPL23 PE=1 SV=1 5.83 3051.1 - 214696 - - - 0.0483 - 2.661 0.668 - 535.5 1 1 0 0.0001 17 0 0 0 2.74E+06 3.90E+06 - - - 6.381 1 221125_WJC_METTL3_EV_vs_WT_F04.17887.17887.2 5.46E-11 Dec-32 R.FEPSSQMIEVQEGQNLK[136.11].L "sp|Q15155|NOMO1_HUMAN,sp|Q5JPE7|NOMO2_HUMAN,sp|P69849|NOMO3_HUMAN,tr|A0A7I2V3P4|A0A7I2V3P4_HUMAN,tr|A0A7I2V6B0|A0A7I2V6B0_HUMAN,tr|A0A7I2V4T6|A0A7I2V4T6_HUMAN,tr|A0A0G2JP90|A0A0G2JP90_HUMAN,tr|A0A087X117|A0A087X117_HUMAN,tr|A0A0G2JN29|A0A0G2JN29_HUMAN,tr|A0A7I2V2Z5|A0A7I2V2Z5_HUMAN,tr|A0A087WW46|A0A087WW46_HUMAN,tr|J3KN36|J3KN36_HUMAN" 12 1970.9499 2.77 51433 17887 2 1970.949599 986.4822 Nodal modulator 1 OS=Homo sapiens OX=9606 GN=NOMO1 PE=1 SV=5 4.25 3051.3 - 213522 - - - -0.1487 - 2.662 0.683 - 482.9 1 2 0 -0.0003 17 0 0 0 2.69E+06 9.74E+05 - - - 6.4927 0.9999 221125_WJC_METTL3_EV_vs_WT_F04.17891.17891.2 6.72E-05 22-Nov K.LNISFPATGC[160.03]QK.L "sp|P62753|RS6_HUMAN,tr|A2A3R7|A2A3R7_HUMAN" 2 1334.6653 0.76 51435 17891 2 1334.665195 668.3399 40S ribosomal protein S6 OS=Homo sapiens OX=9606 GN=RPS6 PE=1 SV=1 8.22 3051.8 - 7.88E+06 - - - -0.0577 - 2.306 0.478 - 269.5 1 2 0 -0.0001 12 0 0 0 1.03E+08 1.36E+08 - - - 4.7699 0.999 221125_WJC_METTL3_EV_vs_WT_F04.17892.17892.2 1.32E-08 24-Dec R.GYFEYIEENKYSR.A "sp|Q00839|HNRPU_HUMAN,tr|Q5RI18|Q5RI18_HUMAN,tr|A0A1W2PP35|A0A1W2PP35_HUMAN,tr|A0A1W2PPS1|A0A1W2PPS1_HUMAN,tr|A0A1W2PRI6|A0A1W2PRI6_HUMAN" 5 1696.7733 0.6 51436 17892 2 1696.774317 849.3939 Heterogeneous nuclear ribonucleoprotein U OS=Homo sapiens OX=9606 GN=HNRNPU PE=1 SV=6 4.79 3051.9 - 3.42E+06 - - - 0.5982 - 2.648 0.565 - 446 1 2 1 0.001 13 0 0 0 1.33E+08 2.24E+08 - - - 5.7131 1 221125_WJC_METTL3_EV_vs_WT_F04.17893.17893.3 1.03E-06 16/64 K.TPPGLQHEYAAPADYFR.L "sp|Q9BVL2|NUP58_HUMAN,tr|H7BYF2|H7BYF2_HUMAN,tr|Q5JRG1|Q5JRG1_HUMAN" 3 1931.9166 2.94 51437 17893 3 1931.918928 644.9795 Nucleoporin p58\p45 OS=Homo sapiens OX=9606 GN=NUP58 PE=1 SV=1 5.29 3051.9 - 2.64E+06 - - - 1.1988 - 2.985 0.558 - 309.2 1 2 0 0.0023 17 0 0 0 3.14E+07 1.07E+07 - - - 7.5233 0.9998 221125_WJC_METTL3_EV_vs_WT_F04.17894.17894.4 0.00455 Dec-90 K.YFLHDDRDDGVDYWAK.R "sp|Q9NYF8|BCLF1_HUMAN,tr|H0YF14|H0YF14_HUMAN" 2 2013.8857 2.06 51438 17894 4 2013.887211 504.4787 Bcl-2-associated transcription factor 1 OS=Homo sapiens OX=9606 GN=BCLAF1 PE=1 SV=2 4.28 3052 - 1.41E+06 - - - 0.7473 - 2.62 0.472 - 107.5 1 2 1 0.0015 16 0 0 0 2.63E+08 1.27E+08 - - - 3.6732 1 221125_WJC_METTL3_EV_vs_WT_F04.17895.17895.3 8.92E-09 14/36 R.K[136.11]QDSGHLDLR[166.11].N "sp|Q86U44|MTA70_HUMAN,tr|B4E349|B4E349_HUMAN,tr|F5H6D8|F5H6D8_HUMAN,tr|B4DTN4|B4DTN4_HUMAN" 4 1185.6221 0.01 51439 17895 3 1185.621485 396.2146 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 6.75 3052.2 - 1.11E+06 - - - -0.5229 - 2.851 0.549 - 246.6 1 2 0 -0.0006 10 0 0 0 1.27E+05 1.10E+07 - - - 7.7203 0.9457 221125_WJC_METTL3_EV_vs_WT_F04.17897.17897.2 9.01E-07 20-Nov Y.FEYIEENKYSR.A "sp|Q00839|HNRPU_HUMAN,tr|Q5RI18|Q5RI18_HUMAN,tr|A0A1W2PP35|A0A1W2PP35_HUMAN,tr|A0A1W2PPS1|A0A1W2PPS1_HUMAN,tr|A0A1W2PRI6|A0A1W2PRI6_HUMAN" 5 1476.6885 0.88 51441 17897 2 1476.688678 739.3515 Heterogeneous nuclear ribonucleoprotein U OS=Homo sapiens OX=9606 GN=HNRNPU PE=1 SV=6 4.79 3052.4 - 877589 - - - 0.1144 - 2.121 0.615 - 452.5 1 1 1 0.0002 11 0 0 0 3.08E+07 3.49E+07 - - - 5.6174 0.9999 221125_WJC_METTL3_EV_vs_WT_F04.17898.17898.3 0.0757 Dec-40 K.ELNLSFC[160.03]EIK[136.11]R[166.11].D "sp|P46060|RAGP1_HUMAN,tr|H0Y4Q3|H0Y4Q3_HUMAN" 2 1425.7405 1.16 51442 17898 3 1425.741094 476.2541 Ran GTPase-activating protein 1 OS=Homo sapiens OX=9606 GN=RANGAP1 PE=1 SV=1 6.23 3052.5 - 555457 - - - 0.4131 - 2.397 0.346 - 265.3 1 2 0 0.0006 11 0 0 0 5.88E+06 5.09E+06 - - - 4.8809 0.9986 221125_WJC_METTL3_EV_vs_WT_F04.17900.17900.2 0.135 24-Aug R.FQVITIPQQQSAK.M "sp|Q9BYP7|WNK3_HUMAN,tr|A0A087WYK2|A0A087WYK2_HUMAN" 2 1486.8144 1.98 51444 17900 2 1486.815222 744.4145 Serine\threonine-protein kinase WNK3 OS=Homo sapiens OX=9606 GN=WNK3 PE=1 SV=3 8.75 3052.8 - 455878 - - - 0.5677 - 1.712 0.234 - 176 1 2 0 0.0008 13 0 0 0 4.31E+06 2.18E+06 - - - 2.149 0.998 221125_WJC_METTL3_EV_vs_WT_F04.17901.17901.3 0.00331 Nov-48 K.LKDLFDYSPPLHK.N "sp|Q9NYF8|BCLF1_HUMAN,tr|E9PKI6|E9PKI6_HUMAN,tr|A0A1W2PQ43|A0A1W2PQ43_HUMAN,tr|E9PK91|E9PK91_HUMAN,tr|E9PK09|E9PK09_HUMAN,tr|E9PQN2|E9PQN2_HUMAN" 6 1571.8348 3.1 51445 17901 3 1571.833348 524.9522 Bcl-2-associated transcription factor 1 OS=Homo sapiens OX=9606 GN=BCLAF1 PE=1 SV=2 6.75 3052.9 - 359018 - - - -0.911 - 2.012 0.314 - 120.5 1 2 1 -0.0014 13 0 0 0 8.10E+06 2.61E+06 - - - 3.9359 0.9984 221125_WJC_METTL3_EV_vs_WT_F04.17902.17902.3 0.00651 Aug-48 R.DLHVSTGEFTDLK[136.11].Q sp|O43264|ZW10_HUMAN 1 1468.7289 1.15 51446 17902 3 1468.72775 490.5836 Centromere\kinetochore protein zw10 homolog OS=Homo sapiens OX=9606 GN=ZW10 PE=1 SV=3 4.54 3053 - 369887 - - - -0.7993 - 1.722 0.265 - 71.4 1 2 0 -0.0012 13 0 0 0 3.02E+06 2.62E+06 - - - 2.9677 0.9587 221125_WJC_METTL3_EV_vs_WT_F04.17904.17904.3 0.271 Jul-36 R.SWEQK[136.11]LEEMR[166.11].K "sp|Q16543|CDC37_HUMAN,tr|K7EQA9|K7EQA9_HUMAN,tr|K7EKQ2|K7EKQ2_HUMAN" 3 1352.6514 0.25 51448 17904 3 1352.648925 451.8911 Hsp90 co-chaperone Cdc37 OS=Homo sapiens OX=9606 GN=CDC37 PE=1 SV=1 4.78 3053.3 - 224604 - - - -1.7972 - 1.341 0.245 - 76.2 1 2 1 -0.0024 10 0 0 0 3.15E+05 1.27E+06 - - - 2.1277 1 221125_WJC_METTL3_EV_vs_WT_F04.17909.17909.3 1.31E-09 13/64 K.MSGLHISGGQSVLEPIK.S sp|Q14966|ZN638_HUMAN 1 1751.924 1.01 51452 17909 3 1751.924966 584.9819 Zinc finger protein 638 OS=Homo sapiens OX=9606 GN=ZNF638 PE=1 SV=2 6.5 3053.8 - 1.17E+06 - - - 0.5485 - 2.617 0.549 - 151.1 1 2 0 0.001 17 0 0 0 9.24E+06 9.16E+06 - - - 7.0909 0.9999 221125_WJC_METTL3_EV_vs_WT_F04.17910.17910.4 2.84E-05 13/90 K.YFLHDDR[166.11]DDGVDYWAK[136.11].R "sp|Q9NYF8|BCLF1_HUMAN,tr|H0YF14|H0YF14_HUMAN" 2 2031.9082 2.06 51453 17910 4 2031.907351 508.9843 Bcl-2-associated transcription factor 1 OS=Homo sapiens OX=9606 GN=BCLAF1 PE=1 SV=2 4.28 3053.9 - 2.25E+06 - - - -0.406 - 2.596 0.511 - 114.5 1 2 1 -0.0008 16 0 0 0 2.63E+08 1.27E+08 - - - 4.0096 1 221125_WJC_METTL3_EV_vs_WT_F04.17912.17912.3 6.48E-05 14/40 R.K[136.11]SDGIYIINLK[136.11].R "sp|P08865|RSSA_HUMAN,tr|C9J9K3|C9J9K3_HUMAN,tr|A0A0C4DG17|A0A0C4DG17_HUMAN,tr|F8WD59|F8WD59_HUMAN" 4 1278.7518 0.62 51455 17912 3 1278.750654 427.2579 40S ribosomal protein SA OS=Homo sapiens OX=9606 GN=RPSA PE=1 SV=4 8.5 3054 - 1.57E+06 - - - -0.9259 - 2.49 0.456 - 279.2 1 2 0 -0.0012 11 0 0 0 3.41E+07 5.51E+07 - - - 6.2153 0.9998 221125_WJC_METTL3_EV_vs_WT_F04.17913.17913.3 0.00482 16/56 K.SPAPPLLHVAALGQK.Q "sp|Q8N163|CCAR2_HUMAN,tr|H0YC69|H0YC69_HUMAN,tr|E5RGU7|E5RGU7_HUMAN,tr|E5RFJ3|E5RFJ3_HUMAN,tr|H0YC58|H0YC58_HUMAN" 5 1497.8667 1.1 51456 17913 3 1497.86565 500.2962 Cell cycle and apoptosis regulator protein 2 OS=Homo sapiens OX=9606 GN=CCAR2 PE=1 SV=2 8.49 3054.1 - 1.47E+06 - - - -0.733 - 2.124 0.353 - 198.2 1 2 0 -0.0011 15 0 0 0 1.93E+07 1.76E+07 - - - 4.4409 1 221125_WJC_METTL3_EV_vs_WT_F04.17914.17914.2 2.51E-06 16/18 R.K[136.11]QDSGHLDLR[166.11].N "sp|Q86U44|MTA70_HUMAN,tr|B4E349|B4E349_HUMAN,tr|F5H6D8|F5H6D8_HUMAN,tr|B4DTN4|B4DTN4_HUMAN" 4 1185.6221 0.001 51457 17914 2 1185.620399 593.8183 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 6.75 3054.2 - 1.40E+06 - - - -1.4389 - 2.956 0.589 - 905.8 1 2 0 -0.0017 10 0 0 0 0.00E+00 1.10E+07 - - - 6.4161 1 221125_WJC_METTL3_EV_vs_WT_F04.17915.17915.3 3.11E-12 22/100 A.AAATGSYGAAAAYGAQPSATLAAPYR.T sp|Q96PK6|RBM14_HUMAN 1 2427.1819 4.86 51458 17915 3 2427.18405 810.0679 RNA-binding protein 14 OS=Homo sapiens OX=9606 GN=RBM14 PE=1 SV=2 8.54 3054.3 - 1.36E+06 - - - 0.8907 - 3.873 0.635 - 298.2 1 1 0 0.0022 26 0 0 0 1.05E+07 2.16E+06 - - - 8.7342 1 221125_WJC_METTL3_EV_vs_WT_F04.17916.17916.3 5.49E-07 14/48 K.SLTNDWEDHLAVK[136.11].H "sp|P08238|HS90B_HUMAN,sp|P07900|HS90A_HUMAN" 2 1534.7507 0.71 51459 17916 3 1534.750401 512.5909 Heat shock protein HSP 90-beta OS=Homo sapiens OX=9606 GN=HSP90AB1 PE=1 SV=4 4.53 3054.4 - 1.26E+06 - - - -0.2092 - 2.932 0.544 - 160.4 1 2 0 -0.0003 13 0 0 0 1.42E+08 2.00E+08 - - - 7.5215 1 221125_WJC_METTL3_EV_vs_WT_F04.17917.17917.3 1.74E-07 18/64 K.TPPGLQHEYAAPADYFR[166.11].L "sp|Q9BVL2|NUP58_HUMAN,tr|H7BYF2|H7BYF2_HUMAN,tr|Q5JRG1|Q5JRG1_HUMAN" 3 1941.9249 2.92 51460 17917 3 1941.925441 648.3156 Nucleoporin p58\p45 OS=Homo sapiens OX=9606 GN=NUP58 PE=1 SV=1 5.29 3054.5 - 1.20E+06 - - - 0.2879 - 3.323 0.571 - 421.4 1 2 0 0.0006 17 0 0 0 3.12E+07 1.07E+07 - - - 7.9397 0.9953 221125_WJC_METTL3_EV_vs_WT_F04.17921.17921.2 2.15E-05 22-Nov K.TGQPMINLYTDR[166.11].E "sp|P35637|FUS_HUMAN,tr|H3BPE7|H3BPE7_HUMAN" 2 1417.6899 1.06 51464 17921 2 1417.691863 709.8522 RNA-binding protein FUS OS=Homo sapiens OX=9606 GN=FUS PE=1 SV=1 5.5 3054.9 - 590125 - - - 1.3705 - 2.222 0.048 - 422.2 1 2 0 0.0019 12 0 0 0 1.43E+07 1.35E+07 - - - 1.4957 0.9998 221125_WJC_METTL3_EV_vs_WT_F04.17927.17927.3 0.000503 15/60 K.YFLHDDR[166.11]DDGVDYWAK[136.11].R "sp|Q9NYF8|BCLF1_HUMAN,tr|H0YF14|H0YF14_HUMAN" 2 2031.9082 2.13 51468 17927 3 2031.904518 678.31 Bcl-2-associated transcription factor 1 OS=Homo sapiens OX=9606 GN=BCLAF1 PE=1 SV=2 4.28 3055.6 - 3.81E+06 - - - -1.8003 - 2.635 0.524 - 231.5 1 2 1 -0.0037 16 0 0 0 1.30E+08 6.08E+07 - - - 6.8671 0.9998 221125_WJC_METTL3_EV_vs_WT_F04.17929.17929.3 2.14E-06 14/64 K.MSGLHISGGQSVLEPIK[136.11].S sp|Q14966|ZN638_HUMAN 1 1759.9382 1.01 51470 17929 3 1759.932118 587.6533 Zinc finger protein 638 OS=Homo sapiens OX=9606 GN=ZNF638 PE=1 SV=2 6.5 3055.8 - 1.62E+06 - - - -3.4586 - 2.592 0.501 - 210.8 1 2 0 -0.0061 17 0 0 0 9.24E+06 9.16E+06 - - - 6.5301 0.9999 221125_WJC_METTL3_EV_vs_WT_F04.17930.17930.3 0.00101 14/40 K.ELNLSFC[160.03]EIKR.D "sp|P46060|RAGP1_HUMAN,tr|H0Y4Q3|H0Y4Q3_HUMAN" 2 1407.718 1.17 51471 17930 3 1407.718246 470.2466 Ran GTPase-activating protein 1 OS=Homo sapiens OX=9606 GN=RANGAP1 PE=1 SV=1 6.23 3055.9 - 853198 - - - 0.1499 - 2.427 0.34 - 315.8 1 2 0 0.0002 11 0 0 0 5.97E+06 5.09E+06 - - - 4.8494 0.9998 221125_WJC_METTL3_EV_vs_WT_F04.17931.17931.3 0.000336 14/36 R.TSFLDDAFR[166.11]K[136.11].N "sp|Q14204|DYHC1_HUMAN,tr|A0A7P0T8N2|A0A7P0T8N2_HUMAN,tr|A0A7P0T9C4|A0A7P0T9C4_HUMAN,tr|A0A7P0TBJ7|A0A7P0TBJ7_HUMAN,tr|A0A7P0T9K2|A0A7P0T9K2_HUMAN,tr|A0A2R8Y706|A0A2R8Y706_HUMAN,tr|A0A7P0T916|A0A7P0T916_HUMAN,tr|A0A7P0TB75|A0A7P0TB75_HUMAN,tr|A0A7P0T8W5|A0A7P0T8W5_HUMAN,tr|A0A7P0TAF3|A0A7P0TAF3_HUMAN,tr|A0A7P0T9F1|A0A7P0T9F1_HUMAN,tr|A0A7P0TAW9|A0A7P0TAW9_HUMAN,tr|A0A7P0TA13|A0A7P0TA13_HUMAN,tr|A0A7P0T7V5|A0A7P0T7V5_HUMAN,tr|A0A7P0T9R4|A0A7P0T9R4_HUMAN,tr|A0A2R8Y5T0|A0A2R8Y5T0_HUMAN,tr|A0A2R8YFZ7|A0A2R8YFZ7_HUMAN,tr|A0A2R8Y6H2|A0A2R8Y6H2_HUMAN" 18 1216.6207 0.78 51472 17931 3 1216.617599 406.5475 Cytoplasmic dynein 1 heavy chain 1 OS=Homo sapiens OX=9606 GN=DYNC1H1 PE=1 SV=5 5.63 3056.1 - 780507 - - - -2.5554 - 2.387 0.419 - 305.4 1 2 0 -0.0031 10 0 0 0 6.94E+06 8.87E+06 - - - 5.7515 0.9887 221125_WJC_METTL3_EV_vs_WT_F04.17932.17932.2 7.62E-05 28-Nov Y.TIQGQYAIPQPDLTK.L "sp|Q15366|PCBP2_HUMAN,tr|F8VRH0|F8VRH0_HUMAN,tr|H3BSS4|H3BSS4_HUMAN" 3 1671.8832 1.26 51473 17932 2 1671.884919 836.9489 Poly(rC)-binding protein 2 OS=Homo sapiens OX=9606 GN=PCBP2 PE=1 SV=1 5.5 3056.2 - 498907 - - - 1.0366 - 2.127 0.501 - 250.7 1 1 0 0.0017 15 0 0 0 1.05E+07 8.36E+06 - - - 4.5963 1 221125_WJC_METTL3_EV_vs_WT_F04.17934.17934.3 5.20E-12 21/80 R.VTGEADVEFATHEDAVAAMSK.D "sp|P31943|HNRH1_HUMAN,tr|H0YBD7|H0YBD7_HUMAN,tr|H0YB39|H0YB39_HUMAN,tr|H0YBG7|H0YBG7_HUMAN,tr|E9PCY7|E9PCY7_HUMAN,tr|G8JLB6|G8JLB6_HUMAN" 6 2176.9947 0.86 51474 17934 3 2176.988598 726.6722 Heterogeneous nuclear ribonucleoprotein H OS=Homo sapiens OX=9606 GN=HNRNPH1 PE=1 SV=4 4.17 3056.4 - 420549 - - - -2.7864 - 4.04 0.682 - 501.9 1 2 0 -0.0061 21 0 0 0 4.16E+06 4.82E+06 - - - 9.4894 1 221125_WJC_METTL3_EV_vs_WT_F04.17936.17936.3 1.52E-05 16/72 K.NLPPSGAVPVTGIPPHVVK[136.11].V "sp|Q13283|G3BP1_HUMAN,tr|A0A7I2V5M7|A0A7I2V5M7_HUMAN,tr|A0A7I2YQM1|A0A7I2YQM1_HUMAN,tr|A0A7P0P2U7|A0A7P0P2U7_HUMAN,tr|A0A7I2YQU8|A0A7I2YQU8_HUMAN,tr|A0A7I2V548|A0A7I2V548_HUMAN,tr|A0A7I2V651|A0A7I2V651_HUMAN,tr|A0A7I2V4D8|A0A7I2V4D8_HUMAN,tr|A0A7I2YQN9|A0A7I2YQN9_HUMAN" 9 1886.0869 1.28 51475 17936 3 1886.087053 629.7029 Ras GTPase-activating protein-binding protein 1 OS=Homo sapiens OX=9606 GN=G3BP1 PE=1 SV=1 8.76 3056.6 - 1.09E+06 - - - 0.0716 - 2.4 0.53 - 221.4 1 2 0 0.0001 19 0 0 0 2.99E+07 2.34E+07 - - - 6.5998 0.9999 221125_WJC_METTL3_EV_vs_WT_F04.17938.17938.3 9.48E-06 19/60 K.YFLHDDRDDGVDYWAK.R "sp|Q9NYF8|BCLF1_HUMAN,tr|H0YF14|H0YF14_HUMAN" 2 2013.8857 2.13 51477 17938 3 2013.884065 672.3025 Bcl-2-associated transcription factor 1 OS=Homo sapiens OX=9606 GN=BCLAF1 PE=1 SV=2 4.28 3056.8 - 1.10E+07 - - - -0.8148 - 2.458 0.532 - 321.6 1 2 1 -0.0016 16 0 0 0 1.30E+08 6.08E+07 - - - 6.7784 1 221125_WJC_METTL3_EV_vs_WT_F04.17939.17939.3 3.31E-05 13/40 R.KSDGIYIINLK.R "sp|P08865|RSSA_HUMAN,tr|C9J9K3|C9J9K3_HUMAN,tr|A0A0C4DG17|A0A0C4DG17_HUMAN,tr|F8WD59|F8WD59_HUMAN" 4 1262.7234 0.62 51478 17939 3 1262.722284 421.9151 40S ribosomal protein SA OS=Homo sapiens OX=9606 GN=RPSA PE=1 SV=4 8.5 3056.9 - 2.15E+06 - - - -0.9139 - 2.474 0.467 - 243.6 1 2 0 -0.0012 11 0 0 0 3.42E+07 5.52E+07 - - - 6.3196 1 221125_WJC_METTL3_EV_vs_WT_F04.17940.17940.3 7.28E-07 15/52 R.AENLQLLTENELHR[166.11].Q sp|O94992|HEXI1_HUMAN 1 1688.8721 0.67 51479 17940 3 1688.874509 563.9646 Protein HEXIM1 OS=Homo sapiens OX=9606 GN=HEXIM1 PE=1 SV=1 4.75 3057 - 1.46E+06 - - - 1.4157 - 3.356 0.495 - 406.2 1 2 0 0.0024 14 0 0 0 9.69E+06 1.45E+07 - - - 7.2757 0.9999 221125_WJC_METTL3_EV_vs_WT_F04.17941.17941.3 5.15E-09 16/60 K.LTEDKADVQSIIGLQR.F "sp|Q13263|TIF1B_HUMAN,tr|M0R0K9|M0R0K9_HUMAN" 2 1784.9632 0.83 51480 17941 3 1784.962682 595.995 Transcription intermediary factor 1-beta OS=Homo sapiens OX=9606 GN=TRIM28 PE=1 SV=5 4.56 3057.1 - 1.36E+06 - - - -0.3059 - 3.146 0.456 - 276.3 1 2 1 -0.0005 16 0 0 0 8.74E+06 1.05E+07 - - - 6.5646 1 221125_WJC_METTL3_EV_vs_WT_F04.17943.17943.2 1.53E-10 15/30 K.YGGISTASVDFEQPTR[166.11].D sp|P98175|RBM10_HUMAN 1 1736.8245 3.57 51482 17943 2 1736.826307 869.4195 RNA-binding protein 10 OS=Homo sapiens OX=9606 GN=RBM10 PE=1 SV=3 4.37 3057.4 - 818393 - - - 1.041 - 3.061 0.724 - 788.8 1 2 0 0.0018 16 0 0 0 3.47E+07 9.71E+06 - - - 7.1384 0.9999 221125_WJC_METTL3_EV_vs_WT_F04.17944.17944.3 0.000445 14/36 R.TSFLDDAFRK.N "sp|Q14204|DYHC1_HUMAN,tr|A0A7P0T8N2|A0A7P0T8N2_HUMAN,tr|A0A7P0T9C4|A0A7P0T9C4_HUMAN,tr|A0A7P0TBJ7|A0A7P0TBJ7_HUMAN,tr|A0A7P0T9K2|A0A7P0T9K2_HUMAN,tr|A0A2R8Y706|A0A2R8Y706_HUMAN,tr|A0A7P0T916|A0A7P0T916_HUMAN,tr|A0A7P0TB75|A0A7P0TB75_HUMAN,tr|A0A7P0T8W5|A0A7P0T8W5_HUMAN,tr|A0A7P0TAF3|A0A7P0TAF3_HUMAN,tr|A0A7P0T9F1|A0A7P0T9F1_HUMAN,tr|A0A7P0TAW9|A0A7P0TAW9_HUMAN,tr|A0A7P0TA13|A0A7P0TA13_HUMAN,tr|A0A7P0T7V5|A0A7P0T7V5_HUMAN,tr|A0A7P0T9R4|A0A7P0T9R4_HUMAN,tr|A0A2R8Y5T0|A0A2R8Y5T0_HUMAN,tr|A0A2R8YFZ7|A0A2R8YFZ7_HUMAN,tr|A0A2R8Y6H2|A0A2R8Y6H2_HUMAN" 18 1198.5982 0.78 51483 17944 3 1198.59599 400.54 Cytoplasmic dynein 1 heavy chain 1 OS=Homo sapiens OX=9606 GN=DYNC1H1 PE=1 SV=5 5.63 3057.5 - 683290 - - - -1.8755 - 2.406 0.393 - 324.3 1 2 0 -0.0022 10 0 0 0 6.94E+06 8.87E+06 - - - 5.485 0.9993 221125_WJC_METTL3_EV_vs_WT_F04.17945.17945.3 0.000254 14/68 K.VK[136.11]DGQLTVGLVGYPNVGK[136.11].S "sp|Q9H089|LSG1_HUMAN,tr|H7C2X7|H7C2X7_HUMAN" 2 1859.0487 1.01 51484 17945 3 1859.045386 620.6902 Large subunit GTPase 1 homolog OS=Homo sapiens OX=9606 GN=LSG1 PE=1 SV=2 8.47 3057.6 - 644461 - - - -1.809 - 2.332 0.41 - 174.9 1 2 1 -0.0034 18 0 0 0 5.27E+06 5.24E+06 - - - 5.2186 1 221125_WJC_METTL3_EV_vs_WT_F04.17947.17947.2 5.60E-10 16/28 R.VDDDSLGEFPVTNSR.A "sp|Q92785|REQU_HUMAN,tr|J3KMZ8|J3KMZ8_HUMAN" 2 1649.7533 1.35 51486 17947 2 1649.749564 825.8839 Zinc finger protein ubi-d4 OS=Homo sapiens OX=9606 GN=DPF2 PE=1 SV=2 3.84 3057.9 - 586984 - - - -2.2609 - 3.084 0.685 - 808.5 1 2 0 -0.0037 15 0 0 0 2.02E+07 1.50E+07 - - - 6.8681 1 221125_WJC_METTL3_EV_vs_WT_F04.17948.17948.3 0.00078 14/40 R.R[166.11]QELEQVLGIR[166.11].L "sp|Q92925|SMRD2_HUMAN,tr|B9EGA3|B9EGA3_HUMAN,tr|J3KMX2|J3KMX2_HUMAN,tr|J3QWB6|J3QWB6_HUMAN" 4 1359.7737 0.63 51487 17948 3 1359.773084 454.2652 SWI\SNF-related matrix-associated actin-dependent regulator of chromatin subfamily D member 2 OS=Homo sapiens OX=9606 GN=SMARCD2 PE=1 SV=3 6.14 3058 - 346398 - - - -0.481 - 2.643 0.426 - 561.2 1 2 0 -0.0007 11 0 0 0 2.65E+06 4.23E+06 - - - 6.0503 1 221125_WJC_METTL3_EV_vs_WT_F04.17949.17949.2 6.94E-10 15/28 R.VDDDSLGEFPVTNSR[166.11].A "sp|Q92785|REQU_HUMAN,tr|J3KMZ8|J3KMZ8_HUMAN" 2 1659.7616 1.5 51488 17949 2 1659.758983 830.8881 Zinc finger protein ubi-d4 OS=Homo sapiens OX=9606 GN=DPF2 PE=1 SV=2 3.84 3058.1 - 319521 - - - -1.555 - 3.106 0.697 - 713.2 1 2 0 -0.0026 15 0 0 0 2.96E+07 1.98E+07 - - - 6.9746 0.9999 221125_WJC_METTL3_EV_vs_WT_F04.17951.17951.3 0.0204 19/72 K.NLPPSGAVPVTGIPPHVVK.V "sp|Q13283|G3BP1_HUMAN,tr|A0A7I2V5M7|A0A7I2V5M7_HUMAN,tr|A0A7I2YQM1|A0A7I2YQM1_HUMAN,tr|A0A7P0P2U7|A0A7P0P2U7_HUMAN,tr|A0A7I2YQU8|A0A7I2YQU8_HUMAN,tr|A0A7I2V548|A0A7I2V548_HUMAN,tr|A0A7I2V651|A0A7I2V651_HUMAN,tr|A0A7I2V4D8|A0A7I2V4D8_HUMAN,tr|A0A7I2YQN9|A0A7I2YQN9_HUMAN" 9 1878.0727 1.28 51489 17951 3 1878.07373 627.0315 Ras GTPase-activating protein-binding protein 1 OS=Homo sapiens OX=9606 GN=G3BP1 PE=1 SV=1 8.76 3058.4 - 2.48E+06 - - - 0.5389 - 2.781 0.426 - 319.1 1 2 0 0.001 19 0 0 0 2.99E+07 2.34E+07 - - - 5.802 0.9713 221125_WJC_METTL3_EV_vs_WT_F04.17953.17953.3 2.98E-05 Dec-48 R.GYFEYIEENKYSR[166.11].A "sp|Q00839|HNRPU_HUMAN,tr|Q5RI18|Q5RI18_HUMAN,tr|A0A1W2PP35|A0A1W2PP35_HUMAN,tr|A0A1W2PPS1|A0A1W2PPS1_HUMAN,tr|A0A1W2PRI6|A0A1W2PRI6_HUMAN" 5 1706.7816 - 51490 17953 3 1707.779555 569.9345 Heterogeneous nuclear ribonucleoprotein U OS=Homo sapiens OX=9606 GN=HNRNPU PE=1 SV=6 4.79 3058.6 - 2.02E+06 - - - 584.7163 - 2.214 0.486 - 121.2 1 2 1 0.998 13 0 0 0 - - - - - 5.8369 1 221125_WJC_METTL3_EV_vs_WT_F04.17954.17954.4 4.59E-08 20/90 K.VLHGEQYLELYK[136.11]PLPR[166.11].A "sp|P51659|DHB4_HUMAN,tr|A0A2R8Y7L2|A0A2R8Y7L2_HUMAN,tr|A0A2R8YD50|A0A2R8YD50_HUMAN,tr|A0A804HIR1|A0A804HIR1_HUMAN,tr|E7ET17|E7ET17_HUMAN,tr|E7ER27|E7ER27_HUMAN,tr|E7EPL9|E7EPL9_HUMAN,tr|A0A804HKU2|A0A804HKU2_HUMAN,tr|A0A804HK65|A0A804HK65_HUMAN" 9 1972.0901 0.46 51491 17954 4 1972.088743 494.0298 Peroxisomal multifunctional enzyme type 2 OS=Homo sapiens OX=9606 GN=HSD17B4 PE=1 SV=3 6.73 3058.6 - 1.74E+06 - - - -0.6896 - 3.354 0.612 - 274.6 1 2 0 -0.0014 16 0 0 0 8.39E+06 1.83E+07 - - - 4.9788 1 221125_WJC_METTL3_EV_vs_WT_F04.17955.17955.2 5.55E-09 17/24 K.SLTNDWEDHLAVK.H "sp|P08238|HS90B_HUMAN,sp|P07900|HS90A_HUMAN" 2 1526.7365 0.78 51492 17955 2 1526.737177 764.3755 Heat shock protein HSP 90-beta OS=Homo sapiens OX=9606 GN=HSP90AB1 PE=1 SV=4 4.53 3058.8 - 1.72E+06 - - - 0.429 - 3.253 0.632 - 774.9 1 2 0 0.0007 13 0 0 0 1.29E+07 1.65E+07 - - - 6.7362 0.9998 221125_WJC_METTL3_EV_vs_WT_F04.17956.17956.2 3.58E-08 17/20 R.K[136.11]SDGIYIINLK[136.11].R "sp|P08865|RSSA_HUMAN,tr|C9J9K3|C9J9K3_HUMAN,tr|A0A0C4DG17|A0A0C4DG17_HUMAN,tr|F8WD59|F8WD59_HUMAN" 4 1278.7518 0.89 51493 17956 2 1278.749577 640.3832 40S ribosomal protein SA OS=Homo sapiens OX=9606 GN=RPSA PE=1 SV=4 8.5 3058.9 - 1.47E+06 - - - -1.7681 - 3.351 0.415 - 925.7 1 2 0 -0.0023 11 0 0 0 9.99E+06 1.12E+07 - - - 5.3768 1 221125_WJC_METTL3_EV_vs_WT_F04.17957.17957.2 1.06E-07 16/28 K.ISENMNLQFENQMNK.T sp|Q8IX12|CCAR1_HUMAN 1 1838.8291 11.57 51494 17957 2 1838.829743 920.4218 Cell division cycle and apoptosis regulator protein 1 OS=Homo sapiens OX=9606 GN=CCAR1 PE=1 SV=2 4.53 3059 - 931454 - - - 0.3393 - 3.032 0.623 - 664.3 1 2 0 0.0006 15 0 0 0 8.54E+06 7.38E+05 - - - 6.3694 0.9999 221125_WJC_METTL3_EV_vs_WT_F04.17958.17958.3 7.42E-05 Dec-44 R.NGENGIHFLLNR.D "sp|Q12849|GRSF1_HUMAN,tr|H0YAK1|H0YAK1_HUMAN,tr|H0Y8R1|H0Y8R1_HUMAN,tr|F5H5I6|F5H5I6_HUMAN" 4 1382.7055 1.58 51495 17958 3 1382.705424 461.9091 G-rich sequence factor 1 OS=Homo sapiens OX=9606 GN=GRSF1 PE=1 SV=3 6.75 3059.2 - 872260 - - - -0.0528 - 2.104 0.378 - 282.6 1 2 0 -0.0001 12 0 0 0 9.00E+06 5.71E+06 - - - 4.8161 1 221125_WJC_METTL3_EV_vs_WT_F04.17959.17959.3 1.13E-07 20/52 K.AGGALC[160.03]HILGAAYK.Y "sp|Q92922|SMRC1_HUMAN,tr|F8WE13|F8WE13_HUMAN" 2 1400.7235 1.39 51496 17959 3 1400.721103 467.9151 SWI\SNF complex subunit SMARCC1 OS=Homo sapiens OX=9606 GN=SMARCC1 PE=1 SV=3 8.25 3059.3 - 863999 - - - -1.6791 - 3.745 0.555 - 500.9 1 2 0 -0.0024 14 0 0 0 7.82E+06 5.64E+06 - - - 8.2361 0.9999 221125_WJC_METTL3_EV_vs_WT_F04.17963.17963.3 6.38E-05 Nov-44 R.NGENGIHFLLNR[166.11].D "sp|Q12849|GRSF1_HUMAN,tr|H0YAK1|H0YAK1_HUMAN,tr|H0Y8R1|H0Y8R1_HUMAN,tr|F5H5I6|F5H5I6_HUMAN" 4 1392.7138 1.57 51500 17963 3 1392.713824 465.2452 G-rich sequence factor 1 OS=Homo sapiens OX=9606 GN=GRSF1 PE=1 SV=3 6.75 3059.8 - 607440 - - - 0.0409 - 2.152 0.465 - 218.9 1 2 0 0.0001 12 0 0 0 8.95E+06 5.71E+06 - - - 5.8486 0.9941 221125_WJC_METTL3_EV_vs_WT_F04.17964.17964.2 5.99E-07 13/28 Y.TIQGQYAIPQPDLTK[136.11].L "sp|Q15366|PCBP2_HUMAN,tr|F8VRH0|F8VRH0_HUMAN,tr|H3BSS4|H3BSS4_HUMAN" 3 1679.8974 1.39 51501 17964 2 1679.895986 840.956 Poly(rC)-binding protein 2 OS=Homo sapiens OX=9606 GN=PCBP2 PE=1 SV=1 5.5 3059.9 - 548151 - - - -0.8334 - 2.292 0.602 - 354.8 1 1 0 -0.0014 15 0 0 0 1.05E+07 7.57E+06 - - - 5.5261 1 221125_WJC_METTL3_EV_vs_WT_F04.17965.17965.3 7.55E-10 21/64 K.LLQALAQYQNHLQEQPR[166.11].K "sp|Q9BQG0|MBB1A_HUMAN,tr|I3L1L3|I3L1L3_HUMAN" 2 2059.0838 0.56 51502 17965 3 2059.082783 687.3686 Myb-binding protein 1A OS=Homo sapiens OX=9606 GN=MYBBP1A PE=1 SV=2 6.75 3060.1 - 483410 - - - -0.5143 - 4.375 0.529 - 817.7 1 2 0 -0.0011 17 0 0 0 1.83E+06 3.28E+06 - - - 8.1661 0.9999 221125_WJC_METTL3_EV_vs_WT_F04.17967.17967.3 3.70E-05 Dec-56 R.VDDDSLGEFPVTNSR.A "sp|Q92785|REQU_HUMAN,tr|J3KMZ8|J3KMZ8_HUMAN" 2 1649.7533 2.13 51504 17967 3 1649.753997 550.925 Zinc finger protein ubi-d4 OS=Homo sapiens OX=9606 GN=DPF2 PE=1 SV=2 3.84 3060.3 - 389562 - - - 0.4261 - 1.829 0.488 - 137.1 1 2 0 0.0007 15 0 0 0 4.87E+06 2.29E+06 - - - 5.556 1 221125_WJC_METTL3_EV_vs_WT_F04.17968.17968.2 8.05E-09 28-Nov K.FSPNGEWLASSSADK.L "sp|P61964|WDR5_HUMAN,tr|V9GZ59|V9GZ59_HUMAN" 2 1594.7264 5.56 51505 17968 2 1594.725218 798.3705 WD repeat-containing protein 5 OS=Homo sapiens OX=9606 GN=WDR5 PE=1 SV=1 4.37 3060.5 - 274176 - - - -0.7105 - 2.357 0.662 - 331.3 1 2 0 -0.0011 15 0 0 0 3.22E+06 5.80E+05 - - - 6.0381 1 221125_WJC_METTL3_EV_vs_WT_F04.17971.17971.3 3.65E-08 16/60 K.TGEEIFGTIGMR[166.11]PNAK[136.11].N "sp|Q99873|ANM1_HUMAN,tr|E9PKG1|E9PKG1_HUMAN" 2 1737.8839 1.93 51506 17971 3 1737.881914 580.3019 Protein arginine N-methyltransferase 1 OS=Homo sapiens OX=9606 GN=PRMT1 PE=1 SV=3 5.81 3060.9 - 3.72E+06 - - - -1.1284 - 3.048 0.567 - 336.5 1 2 0 -0.002 16 0 0 0 8.09E+07 4.18E+07 - - - 7.7206 0.9999 221125_WJC_METTL3_EV_vs_WT_F04.17974.17974.2 1.34E-07 22-Nov K.TGQPMINLYTDR.E "sp|P35637|FUS_HUMAN,tr|H3BPE7|H3BPE7_HUMAN" 2 1407.6816 0.99 51509 17974 2 1407.683068 704.8481 RNA-binding protein FUS OS=Homo sapiens OX=9606 GN=FUS PE=1 SV=1 5.5 3061.2 - 990766 - - - 1.0073 - 2.34 0.567 - 376.4 1 2 0 0.0014 12 0 0 0 1.33E+07 1.35E+07 - - - 5.4653 0.9831 221125_WJC_METTL3_EV_vs_WT_F04.17980.17980.2 8.46E-06 Oct-34 F.STAVYSATPVPTPSLPER.T "sp|P82673|RT35_HUMAN,tr|H0YG82|H0YG82_HUMAN" 2 1871.9629 2.48 51515 17980 2 1871.959622 936.9887 "28S ribosomal protein S35, mitochondrial OS=Homo sapiens OX=9606 GN=MRPS35 PE=1 SV=1" 5.72 3061.9 - 603494 - - - -1.7474 - 2.186 0.469 - 181.7 1 1 0 -0.0033 18 0 0 0 9.28E+06 3.74E+06 - - - 4.4268 1 221125_WJC_METTL3_EV_vs_WT_F04.17981.17981.2 1.78E-09 13/30 R.VK[136.11]PAPDETSFSEALLK[136.11].R "sp|Q12905|ILF2_HUMAN,tr|B4DY09|B4DY09_HUMAN,tr|X6R6Z1|X6R6Z1_HUMAN,tr|A0A0A0MRL0|A0A0A0MRL0_HUMAN" 4 1746.9375 1.45 51516 17981 2 1746.934702 874.476 Interleukin enhancer-binding factor 2 OS=Homo sapiens OX=9606 GN=ILF2 PE=1 SV=2 4.68 3062.1 - 389432 - - - -1.5828 - 2.503 0.619 - 286.3 1 2 0 -0.0028 16 0 0 0 8.47E+06 5.84E+06 - - - 5.8678 0.9999 221125_WJC_METTL3_EV_vs_WT_F04.17982.17982.3 0.0197 15/36 K.STFVLDEFKR.K sp|P26641|EF1G_HUMAN 1 1240.6452 0.84 51517 17982 3 1240.64492 414.5557 Elongation factor 1-gamma OS=Homo sapiens OX=9606 GN=EEF1G PE=1 SV=3 5.79 3062.2 - 363952 - - - -0.216 - 2.311 0.408 - 367.8 1 2 0 -0.0003 10 0 0 0 1.21E+07 1.44E+07 - - - 5.5351 0.9993 221125_WJC_METTL3_EV_vs_WT_F04.17983.17983.2 6.51E-07 28-Oct K.FSPNGEWLASSSADK.L "sp|P61964|WDR5_HUMAN,tr|V9GZ59|V9GZ59_HUMAN" 2 1594.7264 5.56 51518 17983 2 1594.720493 798.3705 WD repeat-containing protein 5 OS=Homo sapiens OX=9606 GN=WDR5 PE=1 SV=1 4.37 3062.3 - 354940 - - - -3.6734 - 2.063 0.61 - 244.6 1 2 0 -0.0059 15 0 0 0 3.22E+06 5.80E+05 - - - 5.325 1 221125_WJC_METTL3_EV_vs_WT_F04.17987.17987.3 1.00E-05 Nov-60 R.VKPAPDETSFSEALLK.R "sp|Q12905|ILF2_HUMAN,tr|B4DY09|B4DY09_HUMAN,tr|X6R6Z1|X6R6Z1_HUMAN,tr|A0A0A0MRL0|A0A0A0MRL0_HUMAN" 4 1730.9091 1.43 51521 17987 3 1730.907695 577.977 Interleukin enhancer-binding factor 2 OS=Homo sapiens OX=9606 GN=ILF2 PE=1 SV=2 4.68 3062.8 - 1.45E+07 - - - -0.7926 - 2.855 0.497 - 81.8 1 2 0 -0.0014 16 0 0 0 1.26E+08 8.82E+07 - - - 6.7725 1 221125_WJC_METTL3_EV_vs_WT_F04.17989.17989.3 9.72E-07 21/60 K.TGEEIFGTIGMRPNAK.N "sp|Q99873|ANM1_HUMAN,tr|E9PKG1|E9PKG1_HUMAN" 2 1719.8614 1.8 51523 17989 3 1719.863768 574.2944 Protein arginine N-methyltransferase 1 OS=Homo sapiens OX=9606 GN=PRMT1 PE=1 SV=3 5.81 3063 - 1.04E+07 - - - 1.3739 - 3.724 0.616 - 785.1 1 2 0 0.0024 16 0 0 0 8.13E+07 4.51E+07 - - - 8.7807 0.9997 221125_WJC_METTL3_EV_vs_WT_F04.17990.17990.4 2.62E-06 15/90 K.YYVTIIDAPGHR[166.11]DFIK[136.11].N "sp|P68104|EF1A1_HUMAN,sp|Q5VTE0|EF1A3_HUMAN,tr|A0A7I2V659|A0A7I2V659_HUMAN,tr|A0A7I2V3H3|A0A7I2V3H3_HUMAN,tr|Q5JR01|Q5JR01_HUMAN,tr|A0A7I2V5N4|A0A7I2V5N4_HUMAN,tr|A0A087WVQ9|A0A087WVQ9_HUMAN,tr|A6PW80|A6PW80_HUMAN,tr|A0A087WV01|A0A087WV01_HUMAN" 9 1925.0166 0.37 51524 17990 4 1925.019125 482.2614 Elongation factor 1-alpha 1 OS=Homo sapiens OX=9606 GN=EEF1A1 PE=1 SV=1 6.75 3063 - 2.69E+06 - - - 1.3096 - 2.84 0.446 - 174.8 1 2 1 0.0025 16 0 0 0 5.10E+06 1.38E+07 - - - 3.475 0.9996 221125_WJC_METTL3_EV_vs_WT_F04.17993.17993.4 0.000179 16/90 K.YYVTIIDAPGHRDFIK.N "sp|P68104|EF1A1_HUMAN,sp|Q5VTE0|EF1A3_HUMAN,tr|A0A7I2V659|A0A7I2V659_HUMAN,tr|A0A7I2V3H3|A0A7I2V3H3_HUMAN,tr|Q5JR01|Q5JR01_HUMAN,tr|A0A7I2V5N4|A0A7I2V5N4_HUMAN,tr|A0A087WVQ9|A0A087WVQ9_HUMAN,tr|A6PW80|A6PW80_HUMAN,tr|A0A087WV01|A0A087WV01_HUMAN" 9 1906.9941 0.37 51527 17993 4 1906.997312 477.7558 Elongation factor 1-alpha 1 OS=Homo sapiens OX=9606 GN=EEF1A1 PE=1 SV=1 6.75 3063.3 - 967746 - - - 1.6665 - 2.658 0.429 - 191.9 1 2 1 0.0032 16 0 0 0 5.10E+06 1.38E+07 - - - 3.3035 0.9998 221125_WJC_METTL3_EV_vs_WT_F04.17994.17994.3 1.97E-05 17/60 K.YYVTIIDAPGHR[166.11]DFIK[136.11].N "sp|P68104|EF1A1_HUMAN,sp|Q5VTE0|EF1A3_HUMAN,tr|A0A7I2V659|A0A7I2V659_HUMAN,tr|A0A7I2V3H3|A0A7I2V3H3_HUMAN,tr|Q5JR01|Q5JR01_HUMAN,tr|A0A7I2V5N4|A0A7I2V5N4_HUMAN,tr|A0A087WVQ9|A0A087WVQ9_HUMAN,tr|A6PW80|A6PW80_HUMAN,tr|A0A087WV01|A0A087WV01_HUMAN" 9 1925.0166 0.31 51528 17994 3 1925.021537 642.6795 Elongation factor 1-alpha 1 OS=Homo sapiens OX=9606 GN=EEF1A1 PE=1 SV=1 6.75 3063.4 - 902202 - - - 2.5626 - 3.335 0.508 - 270.1 1 2 1 0.0049 16 0 0 0 2.20E+06 7.02E+06 - - - 7.2928 0.9998 221125_WJC_METTL3_EV_vs_WT_F04.17995.17995.2 1.15E-09 13/28 K.TGGYLTESGYVNLQR[166.11].V sp|Q9H0D6|XRN2_HUMAN 1 1666.819 1.15 51529 17995 2 1666.820097 834.4168 5'-3' exoribonuclease 2 OS=Homo sapiens OX=9606 GN=XRN2 PE=1 SV=1 5.66 3063.5 - 885468 - - - 0.6461 - 2.635 0.43 - 532.4 1 2 0 0.0011 15 0 0 0 6.95E+06 6.03E+06 - - - 4.5987 0.9998 221125_WJC_METTL3_EV_vs_WT_F04.17996.17996.3 6.03E-05 13/56 R.WMEANQHSLNILGQK.V sp|P98175|RBM10_HUMAN 1 1767.8726 2.55 51530 17996 3 1767.878049 590.2982 RNA-binding protein 10 OS=Homo sapiens OX=9606 GN=RBM10 PE=1 SV=3 6.75 3063.7 - 796597 - - - 3.0607 - 2.241 0.464 - 147.6 1 2 0 0.0054 15 0 0 0 2.64E+07 1.04E+07 - - - 5.8172 1 221125_WJC_METTL3_EV_vs_WT_F04.17998.17998.3 0.00091 18/44 K.WIGLDLSNGKPR.D "sp|P17987|TCPA_HUMAN,tr|F5H282|F5H282_HUMAN,tr|E7EQR6|E7EQR6_HUMAN" 3 1354.7357 0.43 51532 17998 3 1354.736542 452.5859 T-complex protein 1 subunit alpha OS=Homo sapiens OX=9606 GN=TCP1 PE=1 SV=1 8.75 3063.9 - 689844 - - - 0.5964 - 3.239 0.442 - 583 1 2 0 0.0008 12 0 0 0 4.92E+07 1.14E+08 - - - 6.7253 0.9616 221125_WJC_METTL3_EV_vs_WT_F04.18001.18001.3 0.00918 Dec-44 R.HVNIDHLHVGWY.Q "sp|O15372|EIF3H_HUMAN,tr|B3KS98|B3KS98_HUMAN,tr|A0A087WZK9|A0A087WZK9_HUMAN,tr|E5RFH0|E5RFH0_HUMAN,tr|E5RGU4|E5RGU4_HUMAN,tr|E5RJT0|E5RJT0_HUMAN" 6 1488.7262 - 51535 18001 3 1488.728133 497.2494 Eukaryotic translation initiation factor 3 subunit H OS=Homo sapiens OX=9606 GN=EIF3H PE=1 SV=1 6.25 3064.2 - 640987 - - - 1.2769 - 2.033 0.334 - 155.4 1 1 0 0.0019 12 0 0 0 - - - - - 4.2299 0.9968 221125_WJC_METTL3_EV_vs_WT_F04.18005.18005.3 7.88E-06 16/60 K.YYVTIIDAPGHRDFIK.N "sp|P68104|EF1A1_HUMAN,sp|Q5VTE0|EF1A3_HUMAN,tr|A0A7I2V659|A0A7I2V659_HUMAN,tr|A0A7I2V3H3|A0A7I2V3H3_HUMAN,tr|Q5JR01|Q5JR01_HUMAN,tr|A0A7I2V5N4|A0A7I2V5N4_HUMAN,tr|A0A087WVQ9|A0A087WVQ9_HUMAN,tr|A6PW80|A6PW80_HUMAN,tr|A0A087WV01|A0A087WV01_HUMAN" 9 1906.9941 0.31 51539 18005 3 1907.005945 636.672 Elongation factor 1-alpha 1 OS=Homo sapiens OX=9606 GN=EEF1A1 PE=1 SV=1 6.75 3064.7 - 339442 - - - 6.1935 - 3.159 0.508 - 227.8 1 2 1 0.0118 16 0 0 0 2.20E+06 7.02E+06 - - - 7.1518 0.9996 221125_WJC_METTL3_EV_vs_WT_F04.18009.18009.2 0.00143 22-Aug K.KWDIC[160.03]AGNAILK.A sp|Q9NX62|IMPA3_HUMAN 1 1387.7282 1.02 51542 18009 2 1387.729401 694.8714 "Golgi-resident adenosine 3',5'-bisphosphate 3'-phosphatase OS=Homo sapiens OX=9606 GN=BPNT2 PE=1 SV=1" 8.2 3065.2 - 383262 - - - 0.8611 - 2.039 0.351 - 141.5 1 2 0 0.0012 12 0 0 0 1.12E+06 1.10E+06 - - - 3.5077 1 221125_WJC_METTL3_EV_vs_WT_F04.18010.18010.3 8.90E-06 15/44 K.WIGLDLSNGK[136.11]PR[166.11].D "sp|P17987|TCPA_HUMAN,tr|F5H282|F5H282_HUMAN,tr|E7EQR6|E7EQR6_HUMAN" 3 1372.7582 0.43 51543 18010 3 1372.759584 458.5933 T-complex protein 1 subunit alpha OS=Homo sapiens OX=9606 GN=TCP1 PE=1 SV=1 8.75 3065.3 - 7.42E+06 - - - 1.0053 - 2.732 0.479 - 409.6 1 2 0 0.0014 12 0 0 0 4.92E+07 1.14E+08 - - - 6.6658 0.9998 221125_WJC_METTL3_EV_vs_WT_F04.18011.18011.3 0.000143 Dec-36 K.STFVLDEFK[136.11]R[166.11].K sp|P26641|EF1G_HUMAN 1 1258.6677 0.84 51544 18011 3 1258.668742 420.5632 Elongation factor 1-gamma OS=Homo sapiens OX=9606 GN=EEF1G PE=1 SV=3 5.79 3065.3 - 3.32E+06 - - - 0.8612 - 2.489 0.325 - 238.1 1 2 0 0.0011 10 0 0 0 1.21E+07 1.44E+07 - - - 4.8262 0.9996 221125_WJC_METTL3_EV_vs_WT_F04.18013.18013.3 2.00E-05 Dec-76 R.ILSAENIPNLPPGGGLAGKR.N "sp|O75688|PPM1B_HUMAN,tr|B8ZZF0|B8ZZF0_HUMAN,tr|A0A3B3IS24|A0A3B3IS24_HUMAN,tr|C9JIR6|C9JIR6_HUMAN" 4 1973.1058 4.68 51546 18013 3 1973.106377 658.7092 Protein phosphatase 1B OS=Homo sapiens OX=9606 GN=PPM1B PE=1 SV=1 8.75 3065.4 - 2.55E+06 - - - 0.2874 - 2.43 0.3 - 137.8 1 2 0 0.0006 20 0 0 0 1.29E+07 2.76E+06 - - - 4.0386 0.9997 221125_WJC_METTL3_EV_vs_WT_F04.18014.18014.2 0.017 16-Sep R.VLDELTLAR.A "sp|Q04695|K1C17_HUMAN,sp|P02533|K1C14_HUMAN,sp|P08727|K1C19_HUMAN,sp|P08779|K1C16_HUMAN,sp|P19012|K1C15_HUMAN,tr|K7EPJ9|K7EPJ9_HUMAN,tr|C9JM50|C9JM50_HUMAN,tr|C9JTG5|C9JTG5_HUMAN,tr|F5GWP8|F5GWP8_HUMAN,tr|K7EMS3|K7EMS3_HUMAN,tr|A8MT21|A8MT21_HUMAN" 11 1028.5866 999 51547 18014 2 1028.587632 515.3006 "Keratin, type I cytoskeletal 17 OS=Homo sapiens OX=9606 GN=KRT17 PE=1 SV=2" 4.37 3065.5 - 1.61E+06 - - - 0.9936 - 2.05 0.39 - 308.9 1 2 0 0.001 9 0 0 0 6.96E+06 0.00E+00 - - - 3.998 1 221125_WJC_METTL3_EV_vs_WT_F04.18015.18015.3 4.95E-07 16/56 R.WMEANQHSLNILGQK[136.11].V sp|P98175|RBM10_HUMAN 1 1775.8868 2.53 51548 18015 3 1775.891418 592.9696 RNA-binding protein 10 OS=Homo sapiens OX=9606 GN=RBM10 PE=1 SV=3 6.75 3065.6 - 1.45E+06 - - - 2.579 - 3.014 0.608 - 286.2 1 2 0 0.0046 15 0 0 0 2.62E+07 1.04E+07 - - - 8.1962 0.9997 221125_WJC_METTL3_EV_vs_WT_F04.18017.18017.3 0.000118 Nov-44 K.TVEIVHIDIADR.S "sp|P48739|PIPNB_HUMAN,tr|B3KYB7|B3KYB7_HUMAN,tr|A0A0A0MSW4|A0A0A0MSW4_HUMAN,tr|B3KYB6|B3KYB6_HUMAN" 4 1379.7409 1.16 51550 18017 3 1379.737254 460.9209 Phosphatidylinositol transfer protein beta isoform OS=Homo sapiens OX=9606 GN=PITPNB PE=1 SV=2 4.53 3065.7 - 1.63E+06 - - - -2.6273 - 2.208 0.406 - 153.6 1 2 0 -0.0036 12 0 0 0 4.12E+06 3.56E+06 - - - 5.261 1 221125_WJC_METTL3_EV_vs_WT_F04.18018.18018.3 6.03E-07 16/48 R.HVISYSLSPFEQR[166.11].A sp|O14949|QCR8_HUMAN 1 1571.7972 1.4 51551 18018 3 1571.797665 524.9397 Cytochrome b-c1 complex subunit 8 OS=Homo sapiens OX=9606 GN=UQCRQ PE=1 SV=4 6.75 3065.8 - 868834 - - - 0.32 - 3.128 0.487 - 512 1 2 0 0.0005 13 0 0 0 3.99E+06 2.85E+06 - - - 7.0614 0.9999 221125_WJC_METTL3_EV_vs_WT_F04.18022.18022.3 1.54E-05 15/48 R.HVISYSLSPFEQR.A sp|O14949|QCR8_HUMAN 1 1561.7889 1.36 51555 18022 3 1561.789585 521.6036 Cytochrome b-c1 complex subunit 8 OS=Homo sapiens OX=9606 GN=UQCRQ PE=1 SV=4 6.75 3066.3 - 690165 - - - 0.4437 - 2.887 0.38 - 424.1 1 2 0 0.0007 13 0 0 0 3.88E+06 2.85E+06 - - - 5.651 0.9739 221125_WJC_METTL3_EV_vs_WT_F04.18025.18025.2 4.18E-07 Sep-34 F.STAVYSATPVPTPSLPER[166.11].T "sp|P82673|RT35_HUMAN,tr|H0YG82|H0YG82_HUMAN" 2 1881.9712 2.45 51558 18025 2 1881.976878 941.9929 "28S ribosomal protein S35, mitochondrial OS=Homo sapiens OX=9606 GN=MRPS35 PE=1 SV=1" 5.72 3066.7 - 392033 - - - 3.0367 - 2.344 0.57 - 135.1 1 1 0 0.0057 18 0 0 0 9.15E+06 3.74E+06 - - - 5.3436 1 221125_WJC_METTL3_EV_vs_WT_F04.18031.18031.2 1.70E-08 16/28 L.SNLQVTQPTVGMNFK.T "sp|P08708|RS17_HUMAN,tr|H3BNC9|H3BNC9_HUMAN" 2 1662.8399 1 51563 18031 2 1662.8429 832.4272 40S ribosomal protein S17 OS=Homo sapiens OX=9606 GN=RPS17 PE=1 SV=2 8.47 3067.4 - 2.56E+06 - - - 1.7795 - 2.985 0.596 - 819.7 1 1 0 0.003 15 0 0 0 1.63E+07 1.63E+07 - - - 6.1308 0.9999 221125_WJC_METTL3_EV_vs_WT_F04.18034.18034.3 2.13E-06 22/56 K.VGEVIVTK[136.11]DDAMLLK[136.11].G "sp|P10809|CH60_HUMAN,tr|A0A7I2V2X6|A0A7I2V2X6_HUMAN,tr|A0A7I2YQK6|A0A7I2YQK6_HUMAN,tr|A0A7I2V599|A0A7I2V599_HUMAN" 4 1645.9295 2.42 51566 18034 3 1645.932285 549.6505 "60 kDa heat shock protein, mitochondrial OS=Homo sapiens OX=9606 GN=HSPD1 PE=1 SV=2" 4.56 3067.6 - 1.50E+06 - - - 1.6647 - 4.271 0.45 - 790.4 1 2 1 0.0027 15 0 0 0 4.31E+07 1.78E+07 - - - 7.3447 1 221125_WJC_METTL3_EV_vs_WT_F04.18035.18035.3 7.21E-09 20/64 K.IEELDQENEAALENGIK.N "sp|P43243|MATR3_HUMAN,tr|B3KM87|B3KM87_HUMAN,tr|A8MXP9|A8MXP9_HUMAN,tr|A0A0R4J2E8|A0A0R4J2E8_HUMAN,tr|D6REM6|D6REM6_HUMAN" 5 1913.9218 1.49 51567 18035 3 1913.923644 638.9812 Matrin-3 OS=Homo sapiens OX=9606 GN=MATR3 PE=1 SV=2 3.83 3067.7 - 1.14E+06 - - - 0.9551 - 3.535 0.648 - 628.2 1 2 0 0.0018 17 0 0 0 1.54E+07 1.03E+07 - - - 8.954 1 221125_WJC_METTL3_EV_vs_WT_F04.18037.18037.2 1.75E-05 20/32 K.IEELDQENEAALENGIK.N "sp|P43243|MATR3_HUMAN,tr|B3KM87|B3KM87_HUMAN,tr|A8MXP9|A8MXP9_HUMAN,tr|A0A0R4J2E8|A0A0R4J2E8_HUMAN,tr|D6REM6|D6REM6_HUMAN" 5 1913.9218 1.83 51569 18037 2 1913.925816 957.9682 Matrin-3 OS=Homo sapiens OX=9606 GN=MATR3 PE=1 SV=2 3.83 3067.9 - 1.05E+06 - - - 2.0899 - 3.803 0.608 - 1210.3 1 2 0 0.004 17 0 0 0 1.54E+07 8.41E+06 - - - 6.8145 0.9997 221125_WJC_METTL3_EV_vs_WT_F04.18038.18038.3 0.00124 13/48 R.TQR[166.11]PADVIFATVR[166.11].E sp|P33993|MCM7_HUMAN 1 1492.8265 1.04 51570 18038 3 1492.82989 498.6161 DNA replication licensing factor MCM7 OS=Homo sapiens OX=9606 GN=MCM7 PE=1 SV=4 9.26 3068 - 1.00E+06 - - - 2.2695 - 2.678 0.335 - 248.4 1 2 0 0.0034 13 0 0 0 2.26E+07 2.17E+07 - - - 4.9448 1 221125_WJC_METTL3_EV_vs_WT_F04.18040.18040.3 1.72E-07 19/72 R.NLESHLMSPAEIPGQPVPK.N "sp|Q9NRA8|4ET_HUMAN,tr|B0QYZ7|B0QYZ7_HUMAN" 2 2043.0459 1.3 51572 18040 3 2043.046888 682.0226 Eukaryotic translation initiation factor 4E transporter OS=Homo sapiens OX=9606 GN=EIF4ENIF1 PE=1 SV=2 5.4 3068.2 - 785813 - - - 0.4782 - 3.498 0.535 - 330.6 1 2 0 0.001 19 0 0 0 4.29E+07 3.29E+07 - - - 7.5808 0.9925 221125_WJC_METTL3_EV_vs_WT_F04.18042.18042.3 0.0795 Oct-40 K.KMIGEFVSDRK.N "sp|Q92538|GBF1_HUMAN,tr|A0A7I2V2L4|A0A7I2V2L4_HUMAN,tr|A0A7I2V5C9|A0A7I2V5C9_HUMAN,tr|A0A7I2YQM2|A0A7I2YQM2_HUMAN,tr|A0A7I2V3Y5|A0A7I2V3Y5_HUMAN,tr|A0A669KBG8|A0A669KBG8_HUMAN,tr|A0A7I2V2L5|A0A7I2V2L5_HUMAN,tr|A0A7I2V514|A0A7I2V514_HUMAN,tr|A0A7I2YQ65|A0A7I2YQ65_HUMAN,tr|A0A7I2YQP6|A0A7I2YQP6_HUMAN,tr|A0A669KB10|A0A669KB10_HUMAN,tr|A0A7I2V452|A0A7I2V452_HUMAN,tr|A0A7I2V4K2|A0A7I2V4K2_HUMAN,tr|A0A7I2V3J0|A0A7I2V3J0_HUMAN,tr|A0A7I2V4H1|A0A7I2V4H1_HUMAN,tr|A0A7I2V529|A0A7I2V529_HUMAN,tr|A0A7P0RGV0|A0A7P0RGV0_HUMAN" 17 1308.686 3.17 51574 18042 3 1308.685814 437.2359 Golgi-specific brefeldin A-resistance guanine nucleotide exchange factor 1 OS=Homo sapiens OX=9606 GN=GBF1 PE=1 SV=2 8.59 3068.4 - 677756 - - - -0.1475 - 1.385 0.226 - 83.3 1 2 0 -0.0002 11 0 0 0 1.39E+07 4.40E+06 - - - 1.9849 0.9999 221125_WJC_METTL3_EV_vs_WT_F04.18043.18043.3 0.00593 Nov-44 K.TVEIVHIDIADR[166.11].S "sp|P48739|PIPNB_HUMAN,tr|B3KYB7|B3KYB7_HUMAN,tr|A0A0A0MSW4|A0A0A0MSW4_HUMAN,tr|B3KYB6|B3KYB6_HUMAN" 4 1389.7491 1.16 51575 18043 3 1389.747373 464.257 Phosphatidylinositol transfer protein beta isoform OS=Homo sapiens OX=9606 GN=PITPNB PE=1 SV=2 4.53 3068.6 - 629815 - - - -1.2779 - 2.264 0.372 - 147.7 1 2 0 -0.0018 12 0 0 0 4.12E+06 3.56E+06 - - - 4.9519 0.9802 221125_WJC_METTL3_EV_vs_WT_F04.18044.18044.3 0.228 Nov-40 K.KMIGEFVSDR[166.11]K[136.11].N "sp|Q92538|GBF1_HUMAN,tr|A0A7I2V2L4|A0A7I2V2L4_HUMAN,tr|A0A7I2V5C9|A0A7I2V5C9_HUMAN,tr|A0A7I2YQM2|A0A7I2YQM2_HUMAN,tr|A0A7I2V3Y5|A0A7I2V3Y5_HUMAN,tr|A0A669KBG8|A0A669KBG8_HUMAN,tr|A0A7I2V2L5|A0A7I2V2L5_HUMAN,tr|A0A7I2V514|A0A7I2V514_HUMAN,tr|A0A7I2YQ65|A0A7I2YQ65_HUMAN,tr|A0A7I2YQP6|A0A7I2YQP6_HUMAN,tr|A0A669KB10|A0A669KB10_HUMAN,tr|A0A7I2V452|A0A7I2V452_HUMAN,tr|A0A7I2V4K2|A0A7I2V4K2_HUMAN,tr|A0A7I2V3J0|A0A7I2V3J0_HUMAN,tr|A0A7I2V4H1|A0A7I2V4H1_HUMAN,tr|A0A7I2V529|A0A7I2V529_HUMAN,tr|A0A7P0RGV0|A0A7P0RGV0_HUMAN" 17 1326.7085 - 51576 18044 3 1326.709726 443.2434 Golgi-specific brefeldin A-resistance guanine nucleotide exchange factor 1 OS=Homo sapiens OX=9606 GN=GBF1 PE=1 SV=2 8.59 3068.7 - 491716 - - - 0.9414 - 1.292 0.195 - 102.3 1 2 0 0.0013 11 0 0 0 - - - - - 1.4415 0.9794 221125_WJC_METTL3_EV_vs_WT_F04.18045.18045.3 0.785 Oct-44 K.WIGLDLSNGKPR[166.11].D "sp|P17987|TCPA_HUMAN,tr|F5H282|F5H282_HUMAN,tr|E7EQR6|E7EQR6_HUMAN" 3 1364.744 - 51577 18045 3 1364.750235 455.9219 T-complex protein 1 subunit alpha OS=Homo sapiens OX=9606 GN=TCP1 PE=1 SV=1 8.75 3068.8 - 461691 - - - 4.5657 - 1.988 0.223 - 130 1 2 0 0.0062 12 0 0 0 - - - - - 2.9291 0.9986 221125_WJC_METTL3_EV_vs_WT_F04.18048.18048.2 0.0162 28-Aug R.GALQNIIPASTGAAK.A "sp|P04406|G3P_HUMAN,tr|E7EUT5|E7EUT5_HUMAN" 2 1410.7831 1.36 51580 18048 2 1410.781572 706.3988 Glyceraldehyde-3-phosphate dehydrogenase OS=Homo sapiens OX=9606 GN=GAPDH PE=1 SV=3 8.75 3069.2 - 325272 - - - -1.0675 - 1.491 0.303 - 116.3 1 2 0 -0.0015 15 0 0 0 6.63E+06 4.88E+06 - - - 2.2605 0.9999 221125_WJC_METTL3_EV_vs_WT_F04.18051.18051.2 2.60E-07 22-Oct K.LLDLVQQSC[160.03]NYK.Q "sp|P55769|NH2L1_HUMAN,tr|B1AHD1|B1AHD1_HUMAN,tr|A0A3B3IUA2|A0A3B3IUA2_HUMAN" 3 1479.7392 0.84 51582 18051 2 1479.741056 740.8769 NHP2-like protein 1 OS=Homo sapiens OX=9606 GN=SNU13 PE=1 SV=3 5.83 3069.6 - 318202 - - - 1.2779 - 2.248 0.554 - 310.2 1 2 0 0.0019 12 0 0 0 1.57E+06 1.86E+06 - - - 5.2636 1 221125_WJC_METTL3_EV_vs_WT_F04.18056.18056.2 4.21E-10 Dec-32 R.HVQNGLDSSVNVQGSVL.- sp|Q15007|FL2D_HUMAN 1 1751.8802 - 51587 18056 2 1751.880152 876.9474 Pre-mRNA-splicing regulator WTAP OS=Homo sapiens OX=9606 GN=WTAP PE=1 SV=2 5.08 3069.9 - 2.04E+06 - - - -0.0422 - 2.59 0.621 - 402.2 1 2 0 -0.0001 17 0 0 0 - - - - - 5.9674 1 221125_WJC_METTL3_EV_vs_WT_F04.18058.18058.4 1.61E-05 17/114 K.MIMATNR[166.11]PDTLDPALLR[166.11]PGR[166.11].L "sp|P62333|PRS10_HUMAN,tr|A0A087X2I1|A0A087X2I1_HUMAN" 2 2267.2021 1.23 51589 18058 4 2267.206136 567.8078 26S proteasome regulatory subunit 10B OS=Homo sapiens OX=9606 GN=PSMC6 PE=1 SV=1 9.26 3070 - 1.42E+06 - - - 1.7859 - 2.176 0.523 - 81.4 1 2 0 0.004 20 0 0 0 1.12E+07 9.13E+06 - - - 4.037 0.9933 221125_WJC_METTL3_EV_vs_WT_F04.18060.18060.3 0.000796 Oct-40 E.SLTEELAYLKK.N "sp|P13645|K1C10_HUMAN,tr|A0A1B0GVI3|A0A1B0GVI3_HUMAN" 2 1293.718 21.16 51591 18060 3 1293.719003 432.2466 "Keratin, type I cytoskeletal 10 OS=Homo sapiens OX=9606 GN=KRT10 PE=1 SV=6" 5.86 3070.2 - 738336 - - - 0.7614 - 1.672 0.506 - 109.3 1 1 0 0.001 11 0 0 0 4.02E+06 1.90E+05 - - - 5.6414 1 221125_WJC_METTL3_EV_vs_WT_F04.18061.18061.3 3.35E-07 19/48 R.R[166.11]PQIDPAVEGFIR[166.11].D "sp|Q8WU79|SMAP2_HUMAN,tr|A0A087WV97|A0A087WV97_HUMAN,tr|X6RCC3|X6RCC3_HUMAN" 3 1516.8265 2.79 51592 18061 3 1516.827764 506.6161 Stromal membrane-associated protein 2 OS=Homo sapiens OX=9606 GN=SMAP2 PE=1 SV=1 6.07 3070.4 - 728692 - - - 0.832 - 3.331 0.5 - 750.1 1 2 0 0.0013 13 0 0 0 4.02E+07 1.44E+07 - - - 7.3766 0.9338 221125_WJC_METTL3_EV_vs_WT_F04.18063.18063.3 0.192 Oct-48 R.K[136.11]RAAMSVTLTSVK[136.11].R "tr|C9JWC3|C9JWC3_HUMAN,tr|C9J9D3|C9J9D3_HUMAN,tr|C9J372|C9J372_HUMAN,tr|C9JZ60|C9JZ60_HUMAN,tr|C9JG84|C9JG84_HUMAN,tr|C9J4Z9|C9J4Z9_HUMAN,tr|C9JN77|C9JN77_HUMAN" 7 1406.825 - 51594 18063 3 1406.827389 469.9489 Sorbin and SH3 domain-containing protein 2 (Fragment) OS=Homo sapiens OX=9606 GN=SORBS2 PE=1 SV=1 11.17 3070.6 - 549644 - - - 1.6839 - 1.991 0.128 - 123.2 1 2 1 0.0024 13 0 0 0 - - - - - 1.8335 1 221125_WJC_METTL3_EV_vs_WT_F04.18064.18064.2 1.88E-10 19/32 K.TAANLVVETGQDGVQIR.S "sp|Q5T3I0|GPTC4_HUMAN,tr|E9PPY4|E9PPY4_HUMAN,tr|F2Z3C6|F2Z3C6_HUMAN,tr|A0A0A0MRK1|A0A0A0MRK1_HUMAN,tr|E9PAV9|E9PAV9_HUMAN" 5 1769.9272 1.61 51595 18064 2 1769.935781 885.9709 G patch domain-containing protein 4 OS=Homo sapiens OX=9606 GN=GPATCH4 PE=1 SV=2 4.37 3070.7 - 414021 - - - 4.8618 - 3.568 0.621 - 1081.5 1 2 0 0.0086 17 0 0 0 1.09E+07 6.76E+06 - - - 6.7523 0.9877 221125_WJC_METTL3_EV_vs_WT_F04.18066.18066.2 2.16E-05 30-Nov R.GLSPAQADSQFLENAK[136.11].R "sp|O43491|E41L2_HUMAN,tr|A0A2R8Y5B3|A0A2R8Y5B3_HUMAN,tr|E9PII3|E9PII3_HUMAN,tr|E9PHY5|E9PHY5_HUMAN,tr|E9PK52|E9PK52_HUMAN" 5 1682.8355 1.25 51597 18066 2 1682.823378 842.425 Band 4.1-like protein 2 OS=Homo sapiens OX=9606 GN=EPB41L2 PE=1 SV=1 4.37 3071 - 305957 - - - -7.2116 - 2.134 0.497 - 283.3 1 2 0 -0.0121 16 0 0 0 1.79E+06 1.43E+06 - - - 4.5716 0.9997 221125_WJC_METTL3_EV_vs_WT_F04.18068.18068.2 0.000475 22-Oct K.SPYQEFTDHLVK[136.11].T "sp|P15880|RS2_HUMAN,tr|E9PQD7|E9PQD7_HUMAN,tr|H0YEN5|H0YEN5_HUMAN" 3 1470.7234 1.05 51599 18068 2 1470.725432 736.369 40S ribosomal protein S2 OS=Homo sapiens OX=9606 GN=RPS2 PE=1 SV=2 5.3 3071.3 - 246266 - - - 1.351 - 2.059 0.439 - 234.5 1 2 0 0.002 12 0 0 0 7.82E+06 7.45E+06 - - - 4.1831 0.9999 221125_WJC_METTL3_EV_vs_WT_F04.18072.18072.3 4.60E-05 13/72 R.NLESHLMSPAEIPGQPVPK[136.11].N "sp|Q9NRA8|4ET_HUMAN,tr|B0QYZ7|B0QYZ7_HUMAN" 2 2051.0601 1.3 51601 18072 3 2051.06293 684.694 Eukaryotic translation initiation factor 4E transporter OS=Homo sapiens OX=9606 GN=EIF4ENIF1 PE=1 SV=2 5.4 3071.8 - 2.74E+06 - - - 1.3744 - 2.563 0.474 - 145.7 1 2 0 0.0028 19 0 0 0 4.29E+07 3.29E+07 - - - 6.1361 1 221125_WJC_METTL3_EV_vs_WT_F04.18074.18074.3 1.61E-07 15/64 K.TAANLVVETGQDGVQIR[166.11].S "sp|Q5T3I0|GPTC4_HUMAN,tr|E9PPY4|E9PPY4_HUMAN,tr|F2Z3C6|F2Z3C6_HUMAN,tr|A0A0A0MRK1|A0A0A0MRK1_HUMAN,tr|E9PAV9|E9PAV9_HUMAN" 5 1779.9354 1.32 51603 18074 3 1779.938519 594.3191 G patch domain-containing protein 4 OS=Homo sapiens OX=9606 GN=GPATCH4 PE=1 SV=2 4.37 3072 - 1.75E+06 - - - 1.7265 - 3.243 0.467 - 343.1 1 2 0 0.0031 17 0 0 0 1.81E+07 1.37E+07 - - - 6.7179 0.9999 221125_WJC_METTL3_EV_vs_WT_F04.18075.18075.3 4.71E-07 14/48 K.NADVLFSSFQKPK.Q sp|Q9P2D1|CHD7_HUMAN 1 1479.7722 0.93 51604 18075 3 1479.773423 494.2647 Chromodomain-helicase-DNA-binding protein 7 OS=Homo sapiens OX=9606 GN=CHD7 PE=1 SV=3 8.59 3072 - 1.66E+06 - - - 0.8407 - 2.996 0.328 - 207.7 1 2 0 0.0012 13 0 0 0 2.48E+07 2.65E+07 - - - 5.1716 0.9994 221125_WJC_METTL3_EV_vs_WT_F04.18076.18076.3 2.62E-05 13/44 K.DIEREDIEFIC[160.03]K.T sp|P50991|TCPD_HUMAN 1 1565.7396 0.31 51605 18076 3 1565.740864 522.9205 T-complex protein 1 subunit delta OS=Homo sapiens OX=9606 GN=CCT4 PE=1 SV=4 4.18 3072.1 - 1.43E+06 - - - 0.8335 - 1.922 0.419 - 228.4 1 2 1 0.0013 12 0 0 0 1.53E+07 5.02E+07 - - - 5.0221 0.9942 221125_WJC_METTL3_EV_vs_WT_F04.18077.18077.3 4.64E-05 13/56 K.R[166.11]GLLQDDAHPTLVTY.A "sp|Q86U44|MTA70_HUMAN,tr|F5H6D8|F5H6D8_HUMAN,tr|H0YFV6|H0YFV6_HUMAN,tr|B4DTN4|B4DTN4_HUMAN" 4 1707.882 0.02 51606 18077 3 1707.884296 570.3013 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 5.21 3072.2 - 1.27E+06 - - - 1.3713 - 2.35 0.479 - 209.6 1 1 0 0.0023 15 0 0 0 1.97E+06 8.75E+07 - - - 6.1092 1 221125_WJC_METTL3_EV_vs_WT_F04.18078.18078.3 2.44E-07 19/72 R.VSPEEVTIYNHPGIQAELR.L sp|Q8TEM1|PO210_HUMAN 1 2151.096 3.58 51607 18078 3 2151.099275 718.0393 Nuclear pore membrane glycoprotein 210 OS=Homo sapiens OX=9606 GN=NUP210 PE=1 SV=3 4.75 3072.3 - 982873 - - - 1.5071 - 3.54 0.474 - 382.4 1 2 0 0.0032 19 0 0 0 1.16E+07 3.24E+06 - - - 6.9294 1 221125_WJC_METTL3_EV_vs_WT_F04.18079.18079.3 7.66E-11 24/64 R.SLVNLGGSKSISISVAR.G sp|P04264|K2C1_HUMAN 1 1686.9628 999 51608 18079 3 1686.963911 563.3282 "Keratin, type II cytoskeletal 1 OS=Homo sapiens OX=9606 GN=KRT1 PE=1 SV=6" 11 3072.4 - 883835 - - - 0.6384 - 4.11 0.635 - 625.5 1 2 1 0.0011 17 0 0 0 2.33E+07 0.00E+00 - - - 9.1901 1 221125_WJC_METTL3_EV_vs_WT_F04.18080.18080.2 1.72E-10 17/32 K.TAANLVVETGQDGVQIR[166.11].S "sp|Q5T3I0|GPTC4_HUMAN,tr|E9PPY4|E9PPY4_HUMAN,tr|F2Z3C6|F2Z3C6_HUMAN,tr|A0A0A0MRK1|A0A0A0MRK1_HUMAN,tr|E9PAV9|E9PAV9_HUMAN" 5 1779.9354 1.61 51609 18080 2 1779.935939 890.975 G patch domain-containing protein 4 OS=Homo sapiens OX=9606 GN=GPATCH4 PE=1 SV=2 4.37 3072.5 - 866294 - - - 0.277 - 3.539 0.602 - 840.3 1 2 0 0.0005 17 0 0 0 1.09E+07 6.76E+06 - - - 6.5944 1 221125_WJC_METTL3_EV_vs_WT_F04.18081.18081.2 1.08E-08 15/26 R.NLGSINTELQDVQR[166.11].L "sp|O75396|SC22B_HUMAN,tr|A0A087X1A9|A0A087X1A9_HUMAN" 2 1595.8143 1.21 51610 18081 2 1595.81579 798.9144 Vesicle-trafficking protein SEC22b OS=Homo sapiens OX=9606 GN=SEC22B PE=1 SV=5 4.37 3072.7 - 529244 - - - 0.9531 - 3.067 0.62 - 797.3 1 2 0 0.0015 14 0 0 0 2.12E+07 1.74E+07 - - - 6.4322 0.9908 221125_WJC_METTL3_EV_vs_WT_F04.18083.18083.2 1.49E-05 30-Nov R.GLSNPNELQAAIDSNR.R "sp|Q99856|ARI3A_HUMAN,tr|K7EJ04|K7EJ04_HUMAN" 2 1697.8333 999 51612 18083 2 1697.839747 849.9239 AT-rich interactive domain-containing protein 3A OS=Homo sapiens OX=9606 GN=ARID3A PE=1 SV=2 4.37 3072.9 - 378770 - - - 3.8113 - 2.35 0.154 - 339.7 1 2 0 0.0065 16 0 0 0 2.99E+06 0.00E+00 - - - 2.277 0.9918 221125_WJC_METTL3_EV_vs_WT_F04.18085.18085.3 5.57E-08 14/68 K.AKADALYPVVSAASIC[160.03]AK.V sp|O75792|RNH2A_HUMAN 1 1833.9659 1.26 51614 18085 3 1833.979215 612.3292 Ribonuclease H2 subunit A OS=Homo sapiens OX=9606 GN=RNASEH2A PE=1 SV=2 8.22 3073.2 - 268576 - - - 7.2766 - 2.616 0.513 - 244.9 1 2 1 0.0133 18 0 0 0 2.52E+06 1.99E+06 - - - 6.6503 0.9999 221125_WJC_METTL3_EV_vs_WT_F04.18090.18090.3 2.28E-05 Nov-44 K.DIER[166.11]EDIEFIC[160.03]K[136.11].T sp|P50991|TCPD_HUMAN 1 1583.762 0.32 51618 18090 3 1583.76313 528.928 T-complex protein 1 subunit delta OS=Homo sapiens OX=9606 GN=CCT4 PE=1 SV=4 4.18 3073.8 - 7.87E+06 - - - 0.6952 - 2.472 0.496 - 145 1 2 1 0.0011 12 0 0 0 1.51E+07 4.71E+07 - - - 6.5782 0.9999 221125_WJC_METTL3_EV_vs_WT_F04.18092.18092.3 4.06E-08 13/60 R.ELVFK[136.11]EDGQEYAQVIK[136.11].M "sp|O14602|IF1AY_HUMAN,sp|P47813|IF1AX_HUMAN,tr|A6NJH9|A6NJH9_HUMAN" 3 1910.996 0.69 51619 18092 3 1910.997493 638.006 "Eukaryotic translation initiation factor 1A, Y-chromosomal OS=Homo sapiens OX=9606 GN=EIF1AY PE=1 SV=4" 4.41 3074 - 5.88E+06 - - - 0.7582 - 2.572 0.557 - 199.3 1 2 1 0.0014 16 0 0 0 1.69E+08 2.44E+08 - - - 7.1735 1 221125_WJC_METTL3_EV_vs_WT_F04.18093.18093.3 1.04E-08 17/64 K.TAANLVVETGQDGVQIR.S "sp|Q5T3I0|GPTC4_HUMAN,tr|E9PPY4|E9PPY4_HUMAN,tr|F2Z3C6|F2Z3C6_HUMAN,tr|A0A0A0MRK1|A0A0A0MRK1_HUMAN,tr|E9PAV9|E9PAV9_HUMAN" 5 1769.9272 1.32 51620 18093 3 1769.930897 590.983 G patch domain-containing protein 4 OS=Homo sapiens OX=9606 GN=GPATCH4 PE=1 SV=2 4.37 3074.1 - 3.11E+06 - - - 2.1023 - 3.385 0.56 - 449.4 1 2 0 0.0037 17 0 0 0 1.81E+07 1.37E+07 - - - 7.8629 1 221125_WJC_METTL3_EV_vs_WT_F04.18094.18094.2 2.62E-08 15/26 R.NLGSINTELQDVQR.L "sp|O75396|SC22B_HUMAN,tr|A0A087X1A9|A0A087X1A9_HUMAN" 2 1585.806 1.21 51621 18094 2 1585.810656 793.9103 Vesicle-trafficking protein SEC22b OS=Homo sapiens OX=9606 GN=SEC22B PE=1 SV=5 4.37 3074.1 - 1.86E+06 - - - 2.9367 - 2.926 0.576 - 887.3 1 2 0 0.0047 14 0 0 0 2.12E+07 1.74E+07 - - - 5.9881 1 221125_WJC_METTL3_EV_vs_WT_F04.18096.18096.3 2.27E-05 18/68 R.FTAQGLPDLNHSQVYAVK.T sp|Q92900|RENT1_HUMAN 1 1987.0163 1.08 51623 18096 3 1987.019857 663.3461 Regulator of nonsense transcripts 1 OS=Homo sapiens OX=9606 GN=UPF1 PE=1 SV=2 6.74 3074.3 - 1.53E+06 - - - 1.777 - 3.069 0.49 - 406.5 1 2 0 0.0035 18 0 0 0 1.29E+07 1.20E+07 - - - 6.7943 0.9993 221125_WJC_METTL3_EV_vs_WT_F04.18098.18098.4 0.00147 13/114 K.MIMATNRPDTLDPALLRPGR.L "sp|P62333|PRS10_HUMAN,tr|A0A087X2I1|A0A087X2I1_HUMAN" 2 2237.1773 1.2 51625 18098 4 2237.182841 560.3016 26S proteasome regulatory subunit 10B OS=Homo sapiens OX=9606 GN=PSMC6 PE=1 SV=1 9.26 3074.5 - 1.02E+06 - - - 2.4871 - 1.926 0.357 - 42.2 1 2 0 0.0056 20 0 0 0 1.10E+07 9.13E+06 - - - 2.5509 1 221125_WJC_METTL3_EV_vs_WT_F04.18099.18099.2 1.13E-06 24-Dec R.FSGSGSGTDFTLK.L "sp|A2NJV5|KV229_HUMAN,sp|A0A087WW87|KV240_HUMAN,sp|P06310|KV230_HUMAN,sp|A0A075B6S2|KVD29_HUMAN,sp|P01614|KVD40_HUMAN,sp|P01615|KVD28_HUMAN,sp|A0A075B6S6|KVD30_HUMAN,sp|A0A075B6P5|KV228_HUMAN,sp|A0A0A0MRZ7|KVD26_HUMAN" 9 1302.6092 11.25 51626 18099 2 1302.613524 652.3119 Immunoglobulin kappa variable 2-29 OS=Homo sapiens OX=9606 GN=IGKV2-29 PE=3 SV=2 5.84 3074.6 - 852409 - - - 3.3226 - 2.619 0.596 - 303.3 1 2 0 0.0043 13 0 0 0 1.17E+07 1.04E+06 - - - 5.9127 0.9998 221125_WJC_METTL3_EV_vs_WT_F04.18100.18100.3 1.56E-06 Nov-44 R.DRDVDVLSAALK.E sp|Q96ER9|MITOK_HUMAN 1 1300.6987 2.62 51627 18100 3 1300.698567 434.5735 Mitochondrial potassium channel OS=Homo sapiens OX=9606 GN=CCDC51 PE=1 SV=2 4.43 3074.8 - 849698 - - - -0.0869 - 2.147 0.499 - 206.9 1 2 1 -0.0001 12 0 0 0 4.76E+06 1.82E+06 - - - 6.2212 0.9999 221125_WJC_METTL3_EV_vs_WT_F04.18101.18101.3 4.50E-06 14/56 R.HSIAQLDPEALGNIK[136.11].K sp|Q53HL2|BOREA_HUMAN 1 1612.8664 1.6 51628 18101 3 1612.86284 538.6294 Borealin OS=Homo sapiens OX=9606 GN=CDCA8 PE=1 SV=2 5.32 3074.9 - 590219 - - - -2.2203 - 2.871 0.451 - 350.2 1 2 0 -0.0036 15 0 0 0 1.14E+07 7.13E+06 - - - 6.3192 1 221125_WJC_METTL3_EV_vs_WT_F04.18102.18102.2 3.41E-10 17/34 K.LSGSNPYTTVTPQIINSK[136.11].W "sp|O43707|ACTN4_HUMAN,tr|F5GXS2|F5GXS2_HUMAN,tr|H7C144|H7C144_HUMAN" 3 1927.0142 1.8 51629 18102 2 1927.016155 964.5144 Alpha-actinin-4 OS=Homo sapiens OX=9606 GN=ACTN4 PE=1 SV=2 8.59 3075 - 529253 - - - 1.0109 - 3.225 0.633 - 802.2 1 2 0 0.0019 18 0 0 0 8.75E+06 4.85E+06 - - - 6.5945 0.7662 221125_WJC_METTL3_EV_vs_WT_F04.18103.18103.3 0.0229 Dec-44 R.DR[166.11]DVDVLSAALK[136.11].E sp|Q96ER9|MITOK_HUMAN 1 1318.7212 2.62 51630 18103 3 1318.727052 440.581 Mitochondrial potassium channel OS=Homo sapiens OX=9606 GN=CCDC51 PE=1 SV=2 4.43 3075.1 - 527763 - - - 4.4755 - 1.814 0.175 - 219.2 1 2 1 0.0059 12 0 0 0 4.76E+06 1.82E+06 - - - 2.1402 0.8834 221125_WJC_METTL3_EV_vs_WT_F04.18104.18104.2 0.0547 24-Sep R.RNVQALEIELQSQ.L "sp|P13645|K1C10_HUMAN,tr|A0A1B0GVI3|A0A1B0GVI3_HUMAN" 2 1526.8053 999 51631 18104 2 1526.807763 764.4099 "Keratin, type I cytoskeletal 10 OS=Homo sapiens OX=9606 GN=KRT10 PE=1 SV=6" 4.53 3075.2 - 489288 - - - 1.6328 - 1.612 0.265 - 225.8 1 1 0 0.0025 13 0 0 0 4.76E+06 0.00E+00 - - - 2.223 1 221125_WJC_METTL3_EV_vs_WT_F04.18105.18105.3 5.62E-09 20/72 R.VSPEEVTIYNHPGIQAELR[166.11].L sp|Q8TEM1|PO210_HUMAN 1 2161.1043 3.51 51632 18105 3 2161.101673 721.3754 Nuclear pore membrane glycoprotein 210 OS=Homo sapiens OX=9606 GN=NUP210 PE=1 SV=3 4.75 3075.4 - 482928 - - - -1.217 - 3.105 0.581 - 391 1 2 0 -0.0026 19 0 0 0 1.14E+07 3.24E+06 - - - 7.8004 1 221125_WJC_METTL3_EV_vs_WT_F04.18108.18108.3 1.98E-09 15/72 K.FVLC[160.03]PEC[160.03]ENPETDLHVNPK.K "sp|P55010|IF5_HUMAN,tr|H0YLZ1|H0YLZ1_HUMAN,tr|H0YN40|H0YN40_HUMAN" 3 2297.0457 0.96 51635 18108 3 2297.047443 766.6892 Eukaryotic translation initiation factor 5 OS=Homo sapiens OX=9606 GN=EIF5 PE=1 SV=2 4.4 3075.8 - 337714 - - - 0.7788 - 2.981 0.679 - 201.4 1 2 0 0.0018 19 0 0 0 1.50E+07 1.56E+07 - - - 8.7931 0.8915 221125_WJC_METTL3_EV_vs_WT_F04.18111.18111.2 6.75E-08 15/28 C.IPALDSLTPANEDQK.L "sp|P10809|CH60_HUMAN,tr|A0A7I2V2X6|A0A7I2V2X6_HUMAN,tr|A0A7I2YQK6|A0A7I2YQK6_HUMAN,tr|A0A7I2V599|A0A7I2V599_HUMAN" 4 1610.8152 1.03 51638 18111 2 1610.823638 806.4149 "60 kDa heat shock protein, mitochondrial OS=Homo sapiens OX=9606 GN=HSPD1 PE=1 SV=2" 4.03 3076.1 - 283729 - - - 5.2594 - 3.081 0.514 - 629.4 1 1 0 0.0085 15 0 0 0 3.41E+06 3.30E+06 - - - 5.6012 0.9996 221125_WJC_METTL3_EV_vs_WT_F04.18114.18114.3 0.00877 Dec-44 K.EIGNIISDAMK[136.11]K[136.11].V "sp|P10809|CH60_HUMAN,tr|A0A7I2V599|A0A7I2V599_HUMAN,tr|E7EXB4|E7EXB4_HUMAN,tr|A0A7I2YQ71|A0A7I2YQ71_HUMAN,tr|E7ESH4|E7ESH4_HUMAN,tr|A0A7I2V5M1|A0A7I2V5M1_HUMAN,tr|A0A7I2V5K3|A0A7I2V5K3_HUMAN,tr|A0A7I2V369|A0A7I2V369_HUMAN" 8 1333.7246 1.19 51639 18114 3 1333.723678 445.5822 "60 kDa heat shock protein, mitochondrial OS=Homo sapiens OX=9606 GN=HSPD1 PE=1 SV=2" 6.17 3076.5 - 2.61E+06 - - - -0.719 - 1.91 0.327 - 171.8 1 2 0 -0.001 12 0 0 0 6.87E+07 5.80E+07 - - - 3.9791 1 221125_WJC_METTL3_EV_vs_WT_F04.18115.18115.2 3.53E-07 20-Dec K.NC[160.03]AVEFNFGQR.A "sp|Q9BUJ2|HNRL1_HUMAN,tr|M0QYZ0|M0QYZ0_HUMAN,tr|A0A0A0MRA5|A0A0A0MRA5_HUMAN,tr|M0R3F1|M0R3F1_HUMAN,tr|B7Z4B8|B7Z4B8_HUMAN" 5 1340.5932 1.74 51640 18115 2 1340.593277 671.3039 Heterogeneous nuclear ribonucleoprotein U-like protein 1 OS=Homo sapiens OX=9606 GN=HNRNPUL1 PE=1 SV=2 5.99 3076.6 - 2.70E+06 - - - 0.0806 - 2.643 0.652 - 622.1 1 2 0 0.0001 11 0 0 0 1.85E+07 1.06E+07 - - - 6.4859 1 221125_WJC_METTL3_EV_vs_WT_F04.18116.18116.3 9.86E-06 17/56 R.HSIAQLDPEALGNIK.K sp|Q53HL2|BOREA_HUMAN 1 1604.8522 1.59 51641 18116 3 1604.853531 535.958 Borealin OS=Homo sapiens OX=9606 GN=CDCA8 PE=1 SV=2 5.32 3076.7 - 1.70E+06 - - - 0.8163 - 3.135 0.482 - 551.4 1 2 0 0.0013 15 0 0 0 1.12E+07 7.05E+06 - - - 6.895 1 221125_WJC_METTL3_EV_vs_WT_F04.18117.18117.2 2.12E-12 22/30 R.ELVFK[136.11]EDGQEYAQVIK[136.11].M "sp|O14602|IF1AY_HUMAN,sp|P47813|IF1AX_HUMAN,tr|A6NJH9|A6NJH9_HUMAN" 3 1910.996 0.71 51642 18117 2 1910.996202 956.5053 "Eukaryotic translation initiation factor 1A, Y-chromosomal OS=Homo sapiens OX=9606 GN=EIF1AY PE=1 SV=4" 4.41 3076.8 - 1.39E+06 - - - 0.0827 - 3.926 0.624 - 1394.9 1 2 1 0.0002 16 0 0 0 8.00E+06 1.12E+07 - - - 7.0122 0.9986 221125_WJC_METTL3_EV_vs_WT_F04.18118.18118.3 0.00592 Dec-52 K.ALTNLPHTDFTLC[160.03]K[136.11].C "sp|Q9UBQ5|EIF3K_HUMAN,tr|K7EQM4|K7EQM4_HUMAN,tr|A0A087WVB9|A0A087WVB9_HUMAN,tr|K7ERF1|K7ERF1_HUMAN,tr|K7ES31|K7ES31_HUMAN" 5 1637.8327 0.94 51643 18118 3 1637.834628 546.9515 Eukaryotic translation initiation factor 3 subunit K OS=Homo sapiens OX=9606 GN=EIF3K PE=1 SV=1 6.78 3076.9 - 1.33E+06 - - - 1.1906 - 2.303 0.219 - 158.7 1 2 0 0.0019 14 0 0 0 7.04E+06 7.47E+06 - - - 3.198 1 221125_WJC_METTL3_EV_vs_WT_F04.18119.18119.3 1.86E-13 26/76 K.AEAESLYQSKYEELQITAGR.H sp|P04264|K2C1_HUMAN 1 2285.1176 98.76 51644 18119 3 2285.118595 762.7131 "Keratin, type II cytoskeletal 1 OS=Homo sapiens OX=9606 GN=KRT1 PE=1 SV=6" 4.49 3077 - 1.31E+06 - - - 0.4547 - 4.383 0.687 - 822.4 1 2 1 0.001 20 0 0 0 2.38E+07 2.41E+05 - - - 9.7841 0.9998 221125_WJC_METTL3_EV_vs_WT_F04.18121.18121.3 0.000308 13/52 K.ALTNLPHTDFTLC[160.03]K.C "sp|Q9UBQ5|EIF3K_HUMAN,tr|K7EQM4|K7EQM4_HUMAN,tr|A0A087WVB9|A0A087WVB9_HUMAN,tr|K7ERF1|K7ERF1_HUMAN,tr|K7ES31|K7ES31_HUMAN" 5 1629.8185 0.95 51646 18121 3 1629.818371 544.2801 Eukaryotic translation initiation factor 3 subunit K OS=Homo sapiens OX=9606 GN=EIF3K PE=1 SV=1 6.78 3077.2 - 1.23E+06 - - - -0.0657 - 2.419 0.347 - 217.8 1 2 0 -0.0001 14 0 0 0 7.04E+06 7.40E+06 - - - 4.7562 0.9996 221125_WJC_METTL3_EV_vs_WT_F04.18122.18122.3 2.61E-05 15/48 K.EKENLSYDLVPLK.N "sp|Q92598|HS105_HUMAN,tr|A0A0A0MSM0|A0A0A0MSM0_HUMAN,tr|R4GN69|R4GN69_HUMAN" 3 1546.8243 0.12 51647 18122 3 1546.828893 516.6154 Heat shock protein 105 kDa OS=Homo sapiens OX=9606 GN=HSPH1 PE=1 SV=1 4.68 3077.3 - 1.17E+06 - - - 2.9861 - 2.461 0.535 - 257.6 1 2 1 0.0046 13 0 0 0 7.33E+06 6.11E+07 - - - 6.9451 0.8301 221125_WJC_METTL3_EV_vs_WT_F04.18126.18126.2 2.26 30-Sep K.VAVSDSESVSLSGSPK[136.11].S "sp|Q8IVL0|NAV3_HUMAN,tr|A0A2R8YFX5|A0A2R8YFX5_HUMAN,tr|H0YHA8|H0YHA8_HUMAN" 3 1555.7821 0.001 51651 18126 2 1555.788668 778.8983 Neuron navigator 3 OS=Homo sapiens OX=9606 GN=NAV3 PE=1 SV=3 4.37 3077.8 - 930675 - - - 4.2332 - 1.206 0.1 - 103.9 1 2 0 0.0066 16 0 0 0 0.00E+00 5.52E+06 - - - 0.238 1 221125_WJC_METTL3_EV_vs_WT_F04.18127.18127.2 1.64E-10 14/28 K.GSNEEDTDTPLFIGK.V "sp|A6NHR9|SMHD1_HUMAN,tr|J3KTL8|J3KTL8_HUMAN,tr|A0A2R8YE92|A0A2R8YE92_HUMAN" 3 1621.7471 1.56 51652 18127 2 1621.745517 811.8808 Structural maintenance of chromosomes flexible hinge domain-containing protein 1 OS=Homo sapiens OX=9606 GN=SMCHD1 PE=1 SV=2 3.92 3077.9 - 804248 - - - -1.0045 - 2.736 0.721 - 615.8 1 2 0 -0.0016 15 0 0 0 7.77E+06 4.97E+06 - - - 6.8403 1 221125_WJC_METTL3_EV_vs_WT_F04.18128.18128.2 1.32E-08 19/30 R.ELVFKEDGQEYAQVIK.M "sp|O14602|IF1AY_HUMAN,sp|P47813|IF1AX_HUMAN,tr|A6NJH9|A6NJH9_HUMAN" 3 1894.9676 0.71 51653 18128 2 1894.971685 948.4911 "Eukaryotic translation initiation factor 1A, Y-chromosomal OS=Homo sapiens OX=9606 GN=EIF1AY PE=1 SV=4" 4.41 3078 - 781438 - - - 2.1325 - 3.879 0.636 - 1073.1 1 2 1 0.004 16 0 0 0 8.00E+06 1.12E+07 - - - 7.07 1 221125_WJC_METTL3_EV_vs_WT_F04.18129.18129.2 9.98E-06 14/28 K.IIQTPGLWESENQNK.G "sp|Q9NP72|RAB18_HUMAN,tr|Q5W0J0|Q5W0J0_HUMAN,tr|A0A804HKH8|A0A804HKH8_HUMAN,tr|A0A804HL88|A0A804HL88_HUMAN,tr|A0A804HJJ8|A0A804HJJ8_HUMAN,tr|A0A804HIY1|A0A804HIY1_HUMAN" 6 1755.8792 1.61 51654 18129 2 1755.884209 878.9469 Ras-related protein Rab-18 OS=Homo sapiens OX=9606 GN=RAB18 PE=1 SV=1 4.53 3078.2 - 660177 - - - 2.8732 - 2.955 0.567 - 667.9 1 2 0 0.005 15 0 0 0 6.28E+06 3.91E+06 - - - 5.8911 0.9998 221125_WJC_METTL3_EV_vs_WT_F04.18130.18130.3 0.00019 Nov-72 R.YQPLASTASDNDFVTPEPR[166.11].R sp|Q15021|CND1_HUMAN 1 2116.9941 0.96 51655 18130 3 2116.990002 706.672 Condensin complex subunit 1 OS=Homo sapiens OX=9606 GN=NCAPD2 PE=1 SV=3 4.03 3078.3 - 567199 - - - -1.9282 - 1.834 0.452 - 109.6 1 2 0 -0.0041 19 0 0 0 2.09E+06 2.17E+06 - - - 5.0683 0.9513 221125_WJC_METTL3_EV_vs_WT_F04.18133.18133.2 1.24 24-Apr R.TQR[166.11]PADVIFATVR[166.11].E sp|P33993|MCM7_HUMAN 1 1492.8265 1.09 51658 18133 2 1492.823728 747.4205 DNA replication licensing factor MCM7 OS=Homo sapiens OX=9606 GN=MCM7 PE=1 SV=4 9.26 3078.7 - 392248 - - - -1.8582 - 1.155 0.161 - 21.3 22 2 0 -0.0028 13 0 0 0 2.21E+06 2.03E+06 - - - -0.0005 1 221125_WJC_METTL3_EV_vs_WT_F04.18137.18137.3 7.48E-14 23/96 R.AAAASAAEAGIATTGTEDSDDALLK.M "sp|P55036|PSMD4_HUMAN,sp|A2A3N6|PIPSL_HUMAN,tr|H0Y3Y9|H0Y3Y9_HUMAN" 3 2319.1078 1.21 51661 18137 3 2319.107678 774.0432 26S proteasome non-ATPase regulatory subunit 4 OS=Homo sapiens OX=9606 GN=PSMD4 PE=1 SV=1 3.77 3079.1 - 6.38E+06 - - - -0.0436 - 4.531 0.683 - 542.3 1 2 0 -0.0001 25 0 0 0 2.91E+07 2.40E+07 - - - 9.6309 0.9999 221125_WJC_METTL3_EV_vs_WT_F04.18138.18138.3 7.14E-05 15/56 R.TPALVFEHVNNTDFK.Q "sp|P68400|CSK21_HUMAN,sp|Q8NEV1|CSK23_HUMAN,tr|V9GYA2|V9GYA2_HUMAN,tr|A0A2R8YEW1|A0A2R8YEW1_HUMAN,tr|A0A2R8Y4D6|A0A2R8Y4D6_HUMAN,tr|A0A2R8YD58|A0A2R8YD58_HUMAN,tr|A0A2R8YF43|A0A2R8YF43_HUMAN,tr|A0A2R8Y5A0|A0A2R8Y5A0_HUMAN,tr|A0A2R8YDY7|A0A2R8YDY7_HUMAN,tr|A0A2R8Y4H0|A0A2R8Y4H0_HUMAN,tr|E7EU96|E7EU96_HUMAN" 11 1730.8628 0.44 51662 18138 3 1730.856096 577.9615 Casein kinase II subunit alpha OS=Homo sapiens OX=9606 GN=CSNK2A1 PE=1 SV=1 5.29 3079.1 - 2.57E+06 - - - -3.8645 - 3.323 0.527 - 296.3 1 2 0 -0.0067 15 0 0 0 9.03E+06 2.07E+07 - - - 7.5472 1 221125_WJC_METTL3_EV_vs_WT_F04.18139.18139.3 8.55E-06 15/68 R.FTAQGLPDLNHSQVYAVK[136.11].T sp|Q92900|RENT1_HUMAN 1 1995.0305 1.92 51663 18139 3 1995.029636 666.0175 Regulator of nonsense transcripts 1 OS=Homo sapiens OX=9606 GN=UPF1 PE=1 SV=2 6.74 3079.2 - 2.16E+06 - - - -0.4461 - 2.866 0.585 - 290.2 1 2 0 -0.0009 18 0 0 0 2.39E+07 1.24E+07 - - - 7.6838 0.9999 221125_WJC_METTL3_EV_vs_WT_F04.18141.18141.2 2.67E-06 13/22 K.EIGNIISDAMK[136.11]K[136.11].V "sp|P10809|CH60_HUMAN,tr|A0A7I2V599|A0A7I2V599_HUMAN,tr|E7EXB4|E7EXB4_HUMAN,tr|A0A7I2YQ71|A0A7I2YQ71_HUMAN,tr|E7ESH4|E7ESH4_HUMAN,tr|A0A7I2V5M1|A0A7I2V5M1_HUMAN,tr|A0A7I2V5K3|A0A7I2V5K3_HUMAN,tr|A0A7I2V369|A0A7I2V369_HUMAN" 8 1333.7246 1.05 51665 18141 2 1333.724049 667.8696 "60 kDa heat shock protein, mitochondrial OS=Homo sapiens OX=9606 GN=HSPD1 PE=1 SV=2" 6.17 3079.4 - 1.15E+06 - - - -0.4409 - 2.516 0.523 - 538.3 1 2 0 -0.0006 12 0 0 0 8.55E+06 8.14E+06 - - - 5.3314 1 221125_WJC_METTL3_EV_vs_WT_F04.18142.18142.2 1.13E-07 13/24 K.EK[136.11]ENLSYDLVPLK[136.11].N "sp|Q92598|HS105_HUMAN,tr|A0A0A0MSM0|A0A0A0MSM0_HUMAN,tr|R4GN69|R4GN69_HUMAN" 3 1562.8527 0.001 51666 18142 2 1562.852771 782.4336 Heat shock protein 105 kDa OS=Homo sapiens OX=9606 GN=HSPH1 PE=1 SV=1 4.68 3079.5 - 1.10E+06 - - - 0.0621 - 2.679 0.58 - 333.1 1 2 1 0.0001 13 0 0 0 0.00E+00 5.95E+06 - - - 5.854 0.9969 221125_WJC_METTL3_EV_vs_WT_F04.18143.18143.2 0.00257 16-Sep R.LLIYKVSNR.F sp|A0A075B6R9|KVD24_HUMAN 1 1104.6655 999 51667 18143 2 1104.664989 553.34 Probable non-functional immunoglobulin kappa variable 2D-24 OS=Homo sapiens OX=9606 GN=IGKV2D-24 PE=1 SV=1 9.99 3079.7 - 1.05E+06 - - - -0.4888 - 1.972 0.364 - 241.3 1 2 1 -0.0005 9 0 0 0 5.55E+06 0.00E+00 - - - 3.6939 1 221125_WJC_METTL3_EV_vs_WT_F04.18144.18144.2 6.47E-09 15/24 K.VNDTIQIDLETGK.L sp|P62701|RS4X_HUMAN 1 1444.7409 1.36 51668 18144 2 1444.742005 723.3777 "40S ribosomal protein S4, X isoform OS=Homo sapiens OX=9606 GN=RPS4X PE=1 SV=2" 4.03 3079.8 - 1.03E+06 - - - 0.7378 - 3.262 0.631 - 1302 1 2 0 0.0011 13 0 0 0 1.51E+07 1.11E+07 - - - 6.7357 1 221125_WJC_METTL3_EV_vs_WT_F04.18145.18145.2 2.53E-05 14/24 K.VNDTIQIDLETGK[136.11].L sp|P62701|RS4X_HUMAN 1 1452.7551 1.36 51669 18145 2 1452.754878 727.3848 "40S ribosomal protein S4, X isoform OS=Homo sapiens OX=9606 GN=RPS4X PE=1 SV=2" 4.03 3079.9 - 951814 - - - -0.1797 - 3.062 0.562 - 642.5 1 2 0 -0.0003 13 0 0 0 1.51E+07 1.11E+07 - - - 6.064 1 221125_WJC_METTL3_EV_vs_WT_F04.18148.18148.2 1.23E-08 28-Dec K.GSNEEDTDTPLFIGK[136.11].V "sp|A6NHR9|SMHD1_HUMAN,tr|J3KTL8|J3KTL8_HUMAN,tr|A0A2R8YE92|A0A2R8YE92_HUMAN" 3 1629.7613 1.56 51672 18148 2 1629.752913 815.8879 Structural maintenance of chromosomes flexible hinge domain-containing protein 1 OS=Homo sapiens OX=9606 GN=SMCHD1 PE=1 SV=2 3.92 3080.3 - 763179 - - - -5.1744 - 2.352 0.695 - 395.3 1 2 0 -0.0084 15 0 0 0 7.77E+06 4.97E+06 - - - 6.2743 0.9999 221125_WJC_METTL3_EV_vs_WT_F04.18149.18149.2 0.00113 15/28 K.IIQTPGLWESENQNK[136.11].G "sp|Q9NP72|RAB18_HUMAN,tr|Q5W0J0|Q5W0J0_HUMAN,tr|A0A804HKH8|A0A804HKH8_HUMAN,tr|A0A804HL88|A0A804HL88_HUMAN,tr|A0A804HJJ8|A0A804HJJ8_HUMAN,tr|A0A804HIY1|A0A804HIY1_HUMAN" 6 1763.8934 1.61 51673 18149 2 1763.893 882.954 Ras-related protein Rab-18 OS=Homo sapiens OX=9606 GN=RAB18 PE=1 SV=1 4.53 3080.4 - 673872 - - - -0.2064 - 2.791 0.562 - 733.9 1 2 0 -0.0004 15 0 0 0 6.28E+06 3.91E+06 - - - 5.7153 1 221125_WJC_METTL3_EV_vs_WT_F04.18150.18150.2 1.57E-10 13/34 K.LSGSNPYTTVTPQIINSK.W "sp|O43707|ACTN4_HUMAN,tr|F5GXS2|F5GXS2_HUMAN,tr|H7C144|H7C144_HUMAN" 3 1919 1.8 51674 18150 2 1918.995638 960.5073 Alpha-actinin-4 OS=Homo sapiens OX=9606 GN=ACTN4 PE=1 SV=2 8.59 3080.6 - 647433 - - - -2.2767 - 2.588 0.66 - 398.4 1 2 0 -0.0044 18 0 0 0 8.75E+06 4.85E+06 - - - 6.2522 0.9999 221125_WJC_METTL3_EV_vs_WT_F04.18151.18151.2 2.02E-05 14/26 R.DFIIQTGDPTGTGR.G sp|Q8WUA2|PPIL4_HUMAN 1 1476.7209 0.75 51675 18151 2 1476.718623 739.3677 Peptidyl-prolyl cis-trans isomerase-like 4 OS=Homo sapiens OX=9606 GN=PPIL4 PE=1 SV=1 4.21 3080.7 - 612934 - - - -1.523 - 2.332 0.574 - 602.6 1 2 0 -0.0022 14 0 0 0 4.30E+06 5.73E+06 - - - 5.4047 0.9999 221125_WJC_METTL3_EV_vs_WT_F04.18153.18153.4 5.55E-05 30/108 K.LAAAILGGVDQIHIK[136.11]PGAK[136.11].V "sp|P22087|FBRL_HUMAN,tr|M0R299|M0R299_HUMAN,tr|M0R0P1|M0R0P1_HUMAN,tr|M0R1H0|M0R1H0_HUMAN,tr|M0QXL5|M0QXL5_HUMAN,tr|M0R2Q4|M0R2Q4_HUMAN,tr|M0R2B0|M0R2B0_HUMAN,tr|M0R2U2|M0R2U2_HUMAN" 8 1887.1277 0.9 51677 18153 4 1887.124372 472.7892 rRNA 2'-O-methyltransferase fibrillarin OS=Homo sapiens OX=9606 GN=FBL PE=1 SV=2 8.6 3081 - 599206 - - - -1.7466 - 3.898 0.433 - 1100.2 1 2 0 -0.0033 19 0 0 0 2.60E+07 2.89E+07 - - - 3.4541 1 221125_WJC_METTL3_EV_vs_WT_F04.18156.18156.3 3.65E-08 14/44 K.SPYQEFTDHLVK.T "sp|P15880|RS2_HUMAN,tr|E9PQD7|E9PQD7_HUMAN,tr|H0YEN5|H0YEN5_HUMAN" 3 1462.7092 1.01 51679 18156 3 1462.709055 488.577 40S ribosomal protein S2 OS=Homo sapiens OX=9606 GN=RPS2 PE=1 SV=2 5.3 3081.3 - 1.50E+07 - - - -0.1299 - 2.645 0.575 - 217.4 1 2 0 -0.0002 12 0 0 0 1.05E+08 1.04E+08 - - - 7.6467 1 221125_WJC_METTL3_EV_vs_WT_F04.18157.18157.4 9.78E-09 26/108 K.LAAAILGGVDQIHIKPGAK.V "sp|P22087|FBRL_HUMAN,tr|M0R299|M0R299_HUMAN,tr|M0R0P1|M0R0P1_HUMAN,tr|M0R1H0|M0R1H0_HUMAN,tr|M0QXL5|M0QXL5_HUMAN,tr|M0R2Q4|M0R2Q4_HUMAN,tr|M0R2B0|M0R2B0_HUMAN,tr|M0R2U2|M0R2U2_HUMAN" 8 1871.0993 0.9 51680 18157 4 1871.093919 468.7821 rRNA 2'-O-methyltransferase fibrillarin OS=Homo sapiens OX=9606 GN=FBL PE=1 SV=2 8.6 3081.4 - 817578 - - - -2.8587 - 3.988 0.574 - 734.4 1 2 0 -0.0053 19 0 0 0 2.60E+07 2.89E+07 - - - 4.6886 1 221125_WJC_METTL3_EV_vs_WT_F04.18159.18159.3 5.31E-09 16/72 K.FVLC[160.03]PEC[160.03]ENPETDLHVNPK[136.11].K "sp|P55010|IF5_HUMAN,tr|H0YLZ1|H0YLZ1_HUMAN,tr|H0YN40|H0YN40_HUMAN" 3 2305.0599 0.94 51682 18159 3 2305.060461 769.3606 Eukaryotic translation initiation factor 5 OS=Homo sapiens OX=9606 GN=EIF5 PE=1 SV=2 4.4 3081.6 - 1.70E+06 - - - 0.2633 - 3.574 0.69 - 278.7 1 2 0 0.0006 19 0 0 0 1.50E+07 1.59E+07 - - - 9.3618 0.9999 221125_WJC_METTL3_EV_vs_WT_F04.18160.18160.3 4.20E-08 14/52 K.LR[166.11]EIFGLYGQTTGK[136.11].G "sp|Q9NR31|SAR1A_HUMAN,tr|H0Y5E8|H0Y5E8_HUMAN" 2 1599.874 0.96 51683 18160 3 1599.874133 534.2986 GTP-binding protein SAR1a OS=Homo sapiens OX=9606 GN=SAR1A PE=1 SV=1 8.59 3081.6 - 1.70E+06 - - - 0.1069 - 2.763 0.602 - 249.7 1 2 1 0.0002 14 0 0 0 7.91E+07 8.25E+07 - - - 7.9526 1 221125_WJC_METTL3_EV_vs_WT_F04.18161.18161.3 2.66E-10 21/72 R.AFREEFGAEPELAVSAPGR.V "sp|P51570|GALK1_HUMAN,tr|K7ERJ9|K7ERJ9_HUMAN,tr|K7ERN9|K7ERN9_HUMAN,tr|K7EII7|K7EII7_HUMAN" 4 2032.0014 2.19 51684 18161 3 2032.001358 678.3411 Galactokinase OS=Homo sapiens OX=9606 GN=GALK1 PE=1 SV=1 4.49 3081.7 - 1.37E+06 - - - -0.0226 - 3.265 0.64 - 576.1 1 2 1 0 19 0 0 0 4.62E+07 2.11E+07 - - - 8.5824 0.9999 221125_WJC_METTL3_EV_vs_WT_F04.18166.18166.3 0.00022 18/44 K.LALDVEIATYRK.L "sp|P48668|K2C6C_HUMAN,sp|Q01546|K22O_HUMAN,sp|P12035|K2C3_HUMAN,sp|P04259|K2C6B_HUMAN,sp|P13647|K2C5_HUMAN,sp|P35908|K22E_HUMAN,sp|O95678|K2C75_HUMAN,sp|Q5XKE5|K2C79_HUMAN,sp|P02538|K2C6A_HUMAN,tr|H0YI76|H0YI76_HUMAN,tr|H0YID6|H0YID6_HUMAN" 11 1390.782 999 51689 18166 3 1390.782191 464.6013 "Keratin, type II cytoskeletal 6C OS=Homo sapiens OX=9606 GN=KRT6C PE=1 SV=3" 6.07 3082.2 - 928612 - - - 0.1258 - 2.619 0.329 - 461.9 1 2 0 0.0002 12 0 0 0 5.91E+06 0.00E+00 - - - 4.8767 0.9999 221125_WJC_METTL3_EV_vs_WT_F04.18167.18167.2 8.07E-08 13/28 R.YFQINQDEEEEEDED.- "sp|P35268|RL22_HUMAN,tr|K7ERI7|K7ERI7_HUMAN" 2 1930.7228 - 51690 18167 2 1930.720241 966.3687 60S ribosomal protein L22 OS=Homo sapiens OX=9606 GN=RPL22 PE=1 SV=2 3.35 3082.3 - 822759 - - - -1.3472 - 2.555 0.532 - 260 1 2 0 -0.0026 15 0 0 0 - - - - - 5.2758 0.9999 221125_WJC_METTL3_EV_vs_WT_F04.18172.18172.2 3.81E-06 13/26 R.DFIIQTGDPTGTGR[166.11].G sp|Q8WUA2|PPIL4_HUMAN 1 1486.7291 0.9 51695 18172 2 1486.730127 744.3718 Peptidyl-prolyl cis-trans isomerase-like 4 OS=Homo sapiens OX=9606 GN=PPIL4 PE=1 SV=1 4.21 3083 - 683262 - - - 0.6625 - 2.455 0.525 - 529.1 1 2 0 0.001 14 0 0 0 4.30E+06 4.80E+06 - - - 5.1721 1 221125_WJC_METTL3_EV_vs_WT_F04.18174.18174.3 6.84E-09 17/68 R.VALVNDSLSDVTSTTSSR.V "sp|Q7Z2W4|ZCCHV_HUMAN,tr|A0A7P0T8C6|A0A7P0T8C6_HUMAN" 2 1850.9222 0.03 51697 18174 3 1850.923453 617.9813 Zinc finger CCCH-type antiviral protein 1 OS=Homo sapiens OX=9606 GN=ZC3HAV1 PE=1 SV=3 4.21 3083.2 - 546821 - - - 0.7034 - 3.716 0.569 - 392.6 1 2 0 0.0013 18 0 0 0 8.21E+06 2.44E+08 - - - 8.1521 1 221125_WJC_METTL3_EV_vs_WT_F04.18175.18175.2 2.55E-12 19/34 R.VALVNDSLSDVTSTTSSR.V "sp|Q7Z2W4|ZCCHV_HUMAN,tr|A0A7P0T8C6|A0A7P0T8C6_HUMAN" 2 1850.9222 0.01 51698 18175 2 1850.923728 926.4684 Zinc finger CCCH-type antiviral protein 1 OS=Homo sapiens OX=9606 GN=ZC3HAV1 PE=1 SV=3 4.21 3083.3 - 476777 - - - 0.852 - 3.648 0.595 - 1112.6 1 2 0 0.0016 18 0 0 0 3.32E+06 3.15E+08 - - - 6.617 1 221125_WJC_METTL3_EV_vs_WT_F04.18177.18177.3 1.63E-10 18/44 K.SPYQEFTDHLVK[136.11].T "sp|P15880|RS2_HUMAN,tr|E9PQD7|E9PQD7_HUMAN,tr|H0YEN5|H0YEN5_HUMAN" 3 1470.7234 1.01 51699 18177 3 1470.723259 491.2484 40S ribosomal protein S2 OS=Homo sapiens OX=9606 GN=RPS2 PE=1 SV=2 5.3 3083.5 - 1.34E+07 - - - -0.1265 - 3.121 0.661 - 415.3 1 2 0 -0.0002 12 0 0 0 1.05E+08 1.04E+08 - - - 9.0642 0.9999 221125_WJC_METTL3_EV_vs_WT_F04.18179.18179.3 1.83E-07 15/52 K.LREIFGLYGQTTGK.G "sp|Q9NR31|SAR1A_HUMAN,tr|H0Y5E8|H0Y5E8_HUMAN" 2 1581.8515 0.96 51701 18179 3 1581.852022 528.2911 GTP-binding protein SAR1a OS=Homo sapiens OX=9606 GN=SAR1A PE=1 SV=1 8.59 3083.7 - 3.98E+06 - - - 0.3351 - 2.597 0.582 - 266.4 1 2 1 0.0005 14 0 0 0 7.91E+07 8.25E+07 - - - 7.5648 1 221125_WJC_METTL3_EV_vs_WT_F04.18180.18180.3 2.02E-08 18/72 R.AFR[166.11]EEFGAEPELAVSAPGR[166.11].V "sp|P51570|GALK1_HUMAN,tr|K7ERJ9|K7ERJ9_HUMAN,tr|K7ERN9|K7ERN9_HUMAN,tr|K7EII7|K7EII7_HUMAN" 4 2052.0179 2.19 51702 18180 3 2052.016342 685.0133 Galactokinase OS=Homo sapiens OX=9606 GN=GALK1 PE=1 SV=1 4.49 3083.8 - 1.42E+06 - - - -0.7807 - 3.291 0.617 - 411 1 2 1 -0.0016 19 0 0 0 4.62E+07 2.11E+07 - - - 8.345 0.9999 221125_WJC_METTL3_EV_vs_WT_F04.18182.18182.2 0.000478 15/26 K.DQLDETVNVEPLTK.A "sp|Q14203|DCTN1_HUMAN,tr|A0A804CDA6|A0A804CDA6_HUMAN,tr|E7EX90|E7EX90_HUMAN,tr|A0A7P0Z4C3|A0A7P0Z4C3_HUMAN,tr|Q6AWB1|Q6AWB1_HUMAN" 5 1599.7992 2.05 51704 18182 2 1599.799129 800.9069 Dynactin subunit 1 OS=Homo sapiens OX=9606 GN=DCTN1 PE=1 SV=3 3.92 3084 - 689630 - - - -0.0331 - 2.798 0.547 - 619.4 1 2 0 -0.0001 14 0 0 0 3.75E+07 1.83E+07 - - - 5.6631 1 221125_WJC_METTL3_EV_vs_WT_F04.18185.18185.2 1.33E-08 17/26 K.LREIFGLYGQTTGK.G "sp|Q9NR31|SAR1A_HUMAN,tr|H0Y5E8|H0Y5E8_HUMAN" 2 1581.8515 1.23 51707 18185 2 1581.853624 791.933 GTP-binding protein SAR1a OS=Homo sapiens OX=9606 GN=SAR1A PE=1 SV=1 8.59 3084.4 - 334319 - - - 1.3478 - 3.303 0.577 - 645.2 1 2 1 0.0021 14 0 0 0 7.98E+06 6.51E+06 - - - 6.3004 0.8256 221125_WJC_METTL3_EV_vs_WT_F04.18186.18186.3 0.674 Jul-48 R.FIADQLDHLNVTK.K sp|Q9BQC6|RT63_HUMAN 1 1512.7936 1.18 51708 18186 3 1512.789517 505.2718 "Ribosomal protein 63, mitochondrial OS=Homo sapiens OX=9606 GN=MRPL57 PE=1 SV=1" 5.21 3084.6 - 302134 - - - -2.7274 - 1.21 0.168 - 30.5 3 2 0 -0.0041 13 0 0 0 6.15E+06 5.19E+06 - - - 0.7079 0.9975 221125_WJC_METTL3_EV_vs_WT_F04.18187.18187.3 0.0153 Oct-60 K.MLDAEDIVNTARPDEK.A sp|O43707|ACTN4_HUMAN 1 1815.8673 0.63 51709 18187 3 1815.859876 606.2964 Alpha-actinin-4 OS=Homo sapiens OX=9606 GN=ACTN4 PE=1 SV=2 4.1 3084.7 - 243578 - - - -4.0763 - 1.766 0.378 - 84.3 1 2 0 -0.0074 16 0 0 0 3.79E+06 6.04E+06 - - - 4.2115 0.9944 221125_WJC_METTL3_EV_vs_WT_F04.18188.18188.2 0.026 18-Jul K.R[166.11]QDLLNVLAR[166.11].M sp|Q96A33|CCD47_HUMAN 1 1216.7155 1.32 51710 18188 2 1216.71921 609.365 PAT complex subunit CCDC47 OS=Homo sapiens OX=9606 GN=CCDC47 PE=1 SV=1 9.6 3084.8 - 224099 - - - 3.0533 - 1.516 0.275 - 79.3 1 2 0 0.0037 10 0 0 0 2.26E+06 1.72E+06 - - - 2.2324 0.9991 221125_WJC_METTL3_EV_vs_WT_F04.18194.18194.3 0.000113 Nov-40 R.HIEIFTDLSSR[166.11].F "sp|P13010|XRCC5_HUMAN,tr|C9JZ81|C9JZ81_HUMAN" 2 1326.6807 1.2 51714 18194 3 1326.674557 443.2342 X-ray repair cross-complementing protein 5 OS=Homo sapiens OX=9606 GN=XRCC5 PE=1 SV=3 5.32 3085.5 - 1.17E+06 - - - -4.6567 - 2.295 0.416 - 185.7 1 2 0 -0.0062 11 0 0 0 1.11E+07 9.27E+06 - - - 5.5362 1 221125_WJC_METTL3_EV_vs_WT_F04.18195.18195.2 1.42E-08 17/34 K.GSPGVPSFAAGPPISEGK.Y "sp|Q15517|CDSN_HUMAN,tr|G8JLG2|G8JLG2_HUMAN,tr|Q2L6G8|Q2L6G8_HUMAN" 3 1653.8362 200.68 51715 18195 2 1653.839728 827.9254 Corneodesmosin OS=Homo sapiens OX=9606 GN=CDSN PE=1 SV=3 6 3085.6 - 976289 - - - 2.1115 - 2.997 0.636 - 673.4 1 2 0 0.0035 18 0 0 0 2.24E+07 1.12E+05 - - - 6.4359 0.9997 221125_WJC_METTL3_EV_vs_WT_F04.18198.18198.2 0.207 28-Nov R.ALLNLPGTQTSGEAK[136.11].D sp|Q96GM8|TOE1_HUMAN 1 1506.8133 0.78 51718 18198 2 1506.812563 754.4139 Target of EGR1 protein 1 OS=Homo sapiens OX=9606 GN=TOE1 PE=1 SV=1 6.05 3086 - 774727 - - - -0.5037 - 2.638 0.293 - 261.1 1 2 0 -0.0008 15 0 0 0 5.63E+06 7.19E+06 - - - 3.5897 0.9989 221125_WJC_METTL3_EV_vs_WT_F04.18204.18204.3 0.00957 Aug-36 R.APFDLFENK[136.11]K[136.11].K "sp|P08238|HS90B_HUMAN,sp|Q58FF7|H90B3_HUMAN" 2 1223.6521 0.81 51724 18204 3 1223.652448 408.8913 Heat shock protein HSP 90-beta OS=Homo sapiens OX=9606 GN=HSP90AB1 PE=1 SV=4 6.11 3086.8 - 335412 - - - 0.2648 - 1.607 0.298 - 56 1 2 0 0.0003 10 0 0 0 1.89E+06 2.32E+06 - - - 3.2477 0.9928 221125_WJC_METTL3_EV_vs_WT_F04.18205.18205.3 0.00189 Jul-52 R.KILTPIIFKEENLR.T "sp|P82650|RT22_HUMAN,tr|G5E9W7|G5E9W7_HUMAN,tr|A0A7P0MKV3|A0A7P0MKV3_HUMAN,tr|H7C5L9|H7C5L9_HUMAN" 4 1713.0189 1.39 51725 18205 3 1713.022775 572.0136 "28S ribosomal protein S22, mitochondrial OS=Homo sapiens OX=9606 GN=MRPS22 PE=1 SV=1" 8.59 3086.9 - 330013 - - - 2.2668 - 1.539 0.35 - 43.6 1 2 1 0.0039 14 0 0 0 1.76E+06 1.27E+06 - - - 3.5868 0.9999 221125_WJC_METTL3_EV_vs_WT_F04.18207.18207.3 0.000916 Dec-36 R.APFDLFENKK.K "sp|P08238|HS90B_HUMAN,sp|Q58FF7|H90B3_HUMAN" 2 1207.6237 0.81 51727 18207 3 1207.623605 403.5485 Heat shock protein HSP 90-beta OS=Homo sapiens OX=9606 GN=HSP90AB1 PE=1 SV=4 6.11 3087.2 - 211059 - - - -0.0985 - 1.814 0.433 - 139.2 1 2 0 -0.0001 10 0 0 0 1.89E+06 2.32E+06 - - - 5.1067 0.9999 221125_WJC_METTL3_EV_vs_WT_F04.18208.18208.3 0.000313 Nov-36 K.R[166.11]QDLLNVLAR[166.11].M sp|Q96A33|CCD47_HUMAN 1 1216.7155 1.13 51728 18208 3 1216.716298 406.5791 PAT complex subunit CCDC47 OS=Homo sapiens OX=9606 GN=CCDC47 PE=1 SV=1 9.6 3087.3 - 204439 - - - 0.66 - 2.012 0.406 - 230.4 1 2 0 0.0008 10 0 0 0 2.70E+06 2.38E+06 - - - 5.108 1 221125_WJC_METTL3_EV_vs_WT_F04.18214.18214.2 4.15E-05 16/26 K.DQLDETVNVEPLTK[136.11].A "sp|Q14203|DCTN1_HUMAN,tr|A0A804CDA6|A0A804CDA6_HUMAN,tr|E7EX90|E7EX90_HUMAN,tr|A0A7P0Z4C3|A0A7P0Z4C3_HUMAN,tr|Q6AWB1|Q6AWB1_HUMAN" 5 1607.8134 2.05 51732 18214 2 1607.813516 804.914 Dynactin subunit 1 OS=Homo sapiens OX=9606 GN=DCTN1 PE=1 SV=3 3.92 3088.1 - 2.15E+06 - - - 0.0833 - 2.906 0.588 - 759.5 1 2 0 0.0001 14 0 0 0 3.75E+07 1.83E+07 - - - 6.061 1 221125_WJC_METTL3_EV_vs_WT_F04.18215.18215.3 2.14E-10 14/52 R.AHQVVEDGYEFFAK.R "sp|P62136|PP1A_HUMAN,sp|P62140|PP1B_HUMAN,sp|P36873|PP1G_HUMAN,tr|A0A7I2V4F7|A0A7I2V4F7_HUMAN,tr|F8W0W8|F8W0W8_HUMAN,tr|F8VYE8|F8VYE8_HUMAN,tr|E9PMD7|E9PMD7_HUMAN" 7 1638.7678 1.27 51733 18215 3 1638.768369 547.2632 Serine\threonine-protein phosphatase PP1-alpha catalytic subunit OS=Homo sapiens OX=9606 GN=PPP1CA PE=1 SV=1 4.65 3088.1 - 2.04E+06 - - - 0.3338 - 2.715 0.638 - 314.1 1 2 0 0.0005 14 0 0 0 3.90E+07 3.08E+07 - - - 8.3072 1 221125_WJC_METTL3_EV_vs_WT_F04.18218.18218.3 1.92E-11 19/56 K.HNELTGDNVGPLILK.K "sp|Q8N5K1|CISD2_HUMAN,tr|D6RCF4|D6RCF4_HUMAN" 2 1618.8679 0.66 51736 18218 3 1618.867211 540.6299 CDGSH iron-sulfur domain-containing protein 2 OS=Homo sapiens OX=9606 GN=CISD2 PE=1 SV=1 5.32 3088.4 - 1.25E+06 - - - -0.4077 - 3.429 0.583 - 613.4 1 2 0 -0.0007 15 0 0 0 1.13E+07 1.71E+07 - - - 8.2551 1 221125_WJC_METTL3_EV_vs_WT_F04.18219.18219.3 1.89E-05 Dec-36 K.DVDDFFEHER.T "sp|Q9UNH7|SNX6_HUMAN,tr|A0A0A0MRI2|A0A0A0MRI2_HUMAN,tr|G3V5X9|G3V5X9_HUMAN" 3 1307.5418 1.78 51737 18219 3 1307.542011 436.8546 Sorting nexin-6 OS=Homo sapiens OX=9606 GN=SNX6 PE=1 SV=1 4.1 3088.6 - 1.20E+06 - - - 0.127 - 2.182 0.511 - 175.9 1 2 0 0.0002 10 0 0 0 9.41E+06 5.29E+06 - - - 6.5157 1 221125_WJC_METTL3_EV_vs_WT_F04.18221.18221.3 2.21E-06 16/56 K.TQAIVC[160.03]QQLDLTHLK.E "sp|P61221|ABCE1_HUMAN,tr|D6RGF4|D6RGF4_HUMAN,tr|D6R9I9|D6R9I9_HUMAN" 3 1766.9349 0.8 51739 18221 3 1766.938004 589.9856 ATP-binding cassette sub-family E member 1 OS=Homo sapiens OX=9606 GN=ABCE1 PE=1 SV=1 6.4 3088.8 - 1.09E+06 - - - 1.7539 - 3.07 0.472 - 247.1 1 2 0 0.0031 15 0 0 0 9.20E+06 1.16E+07 - - - 6.7283 1 221125_WJC_METTL3_EV_vs_WT_F04.18222.18222.3 2.58E-06 19/48 R.SELPIAELTGHTR.T "sp|Q9H7D7|WDR26_HUMAN,tr|A0A7P0SXD0|A0A7P0SXD0_HUMAN,tr|H0Y9R3|H0Y9R3_HUMAN,tr|A0A7I2YQL3|A0A7I2YQL3_HUMAN,tr|A0A499FIZ0|A0A499FIZ0_HUMAN" 5 1422.7467 0.87 51740 18222 3 1422.747244 475.2562 WD repeat-containing protein 26 OS=Homo sapiens OX=9606 GN=WDR26 PE=1 SV=3 5.38 3088.9 - 939152 - - - 0.3873 - 2.854 0.503 - 589.5 1 2 0 0.0006 13 0 0 0 8.70E+06 1.00E+07 - - - 6.9912 0.9997 221125_WJC_METTL3_EV_vs_WT_F04.18224.18224.3 0.000747 Sep-48 R.FIADQLDHLNVTK[136.11].K sp|Q9BQC6|RT63_HUMAN 1 1520.8078 1.18 51742 18224 3 1520.808834 507.9432 "Ribosomal protein 63, mitochondrial OS=Homo sapiens OX=9606 GN=MRPL57 PE=1 SV=1" 5.21 3089.2 - 598874 - - - 0.6516 - 1.792 0.361 - 61.6 1 2 0 0.001 13 0 0 0 6.15E+06 5.19E+06 - - - 4.1461 0.9928 221125_WJC_METTL3_EV_vs_WT_F04.18225.18225.3 2.04 Apr-56 R.YFQINQDEEEEEDED.- "sp|P35268|RL22_HUMAN,tr|K7ERI7|K7ERI7_HUMAN" 2 1930.7228 - 51743 18225 3 1930.723753 644.5816 60S ribosomal protein L22 OS=Homo sapiens OX=9606 GN=RPL22 PE=1 SV=2 3.35 3089.3 - 592678 - - - 0.4718 - 0.888 0.351 - 16.9 2 2 0 0.0009 15 0 0 0 - - - - - 2.0038 0.9994 221125_WJC_METTL3_EV_vs_WT_F04.18228.18228.3 0.00429 Nov-52 K.DQLDETVNVEPLTK[136.11].A "sp|Q14203|DCTN1_HUMAN,tr|A0A804CDA6|A0A804CDA6_HUMAN,tr|E7EX90|E7EX90_HUMAN,tr|A0A7P0Z4C3|A0A7P0Z4C3_HUMAN,tr|Q6AWB1|Q6AWB1_HUMAN" 5 1607.8134 1.96 51746 18228 3 1607.814364 536.9451 Dynactin subunit 1 OS=Homo sapiens OX=9606 GN=DCTN1 PE=1 SV=3 3.92 3089.7 - 457072 - - - 0.6108 - 1.869 0.309 - 139.9 1 2 0 0.001 14 0 0 0 7.19E+06 3.66E+06 - - - 3.6468 0.9998 221125_WJC_METTL3_EV_vs_WT_F04.18231.18231.2 9.04E-05 30-Oct K.GGITQPNINDSLEITK.L "sp|P30260|CDC27_HUMAN,tr|I3L328|I3L328_HUMAN,tr|G5EA36|G5EA36_HUMAN" 3 1698.8788 0.57 51749 18231 2 1698.879216 850.4467 Cell division cycle protein 27 homolog OS=Homo sapiens OX=9606 GN=CDC27 PE=1 SV=2 4.37 3090.1 - 231865 - - - 0.2278 - 1.815 0.511 - 230.8 1 2 0 0.0004 16 0 0 0 2.69E+06 4.70E+06 - - - 4.2806 1 221125_WJC_METTL3_EV_vs_WT_F04.18234.18234.3 1.25E-11 15/52 R.AHQVVEDGYEFFAK[136.11].R "sp|P62136|PP1A_HUMAN,sp|P62140|PP1B_HUMAN,sp|P36873|PP1G_HUMAN,tr|A0A7I2V4F7|A0A7I2V4F7_HUMAN,tr|F8W0W8|F8W0W8_HUMAN,tr|F8VYE8|F8VYE8_HUMAN,tr|E9PMD7|E9PMD7_HUMAN" 7 1646.782 1.27 51750 18234 3 1646.7819 549.9346 Serine\threonine-protein phosphatase PP1-alpha catalytic subunit OS=Homo sapiens OX=9606 GN=PPP1CA PE=1 SV=1 4.65 3090.5 - 4.46E+06 - - - -0.0741 - 3.216 0.664 - 400.4 1 2 0 -0.0001 14 0 0 0 3.90E+07 3.08E+07 - - - 9.0473 0.9949 221125_WJC_METTL3_EV_vs_WT_F04.18236.18236.3 1.39E-08 18/52 W.ELISNASDALDKIR.Y "sp|Q58FF8|H90B2_HUMAN,sp|P08238|HS90B_HUMAN,sp|Q58FF6|H90B4_HUMAN,sp|Q58FF7|H90B3_HUMAN,sp|P14625|ENPL_HUMAN,tr|A0A7P0T917|A0A7P0T917_HUMAN,tr|A0A7P0Z405|A0A7P0Z405_HUMAN,tr|A0A7P0T823|A0A7P0T823_HUMAN,tr|A0A7P0TAE1|A0A7P0TAE1_HUMAN,tr|H0YIV0|H0YIV0_HUMAN,tr|A0A7P0T8R3|A0A7P0T8R3_HUMAN,tr|A0A7P0T885|A0A7P0T885_HUMAN,tr|A0A7P0TAY2|A0A7P0TAY2_HUMAN,tr|A0A087WT78|A0A087WT78_HUMAN,tr|F8W026|F8W026_HUMAN,tr|A0A7P0TBC2|A0A7P0TBC2_HUMAN,tr|A0A7P0TAT8|A0A7P0TAT8_HUMAN" 17 1543.8206 0.86 51752 18236 3 1543.819872 515.6141 Putative heat shock protein HSP 90-beta 2 OS=Homo sapiens OX=9606 GN=HSP90AB2P PE=1 SV=2 4.56 3090.6 - 1.95E+06 - - - -0.4625 - 3.735 0.55 - 568.1 1 1 1 -0.0007 14 0 0 0 4.12E+07 4.76E+07 - - - 8.1737 1 221125_WJC_METTL3_EV_vs_WT_F04.18237.18237.2 1.78E-09 13/24 R.ESQDTSFTTLVER.V "sp|Q06210|GFPT1_HUMAN,tr|A0A6I8PRN4|A0A6I8PRN4_HUMAN,tr|A0A6I8PTT9|A0A6I8PTT9_HUMAN" 3 1511.7104 1.42 51753 18237 2 1511.710716 756.8625 Glutamine--fructose-6-phosphate aminotransferase [isomerizing] 1 OS=Homo sapiens OX=9606 GN=GFPT1 PE=1 SV=3 4.14 3090.7 - 1.22E+06 - - - 0.2309 - 2.834 0.61 - 816.4 1 2 0 0.0003 13 0 0 0 3.91E+07 2.74E+07 - - - 6.2199 1 221125_WJC_METTL3_EV_vs_WT_F04.18239.18239.2 2.30E-09 15/24 R.ESQDTSFTTLVER[166.11].V "sp|Q06210|GFPT1_HUMAN,tr|A0A6I8PRN4|A0A6I8PRN4_HUMAN,tr|A0A6I8PTT9|A0A6I8PTT9_HUMAN" 3 1521.7186 1.42 51755 18239 2 1521.718246 761.8666 Glutamine--fructose-6-phosphate aminotransferase [isomerizing] 1 OS=Homo sapiens OX=9606 GN=GFPT1 PE=1 SV=3 4.14 3091 - 996604 - - - -0.2569 - 2.958 0.6 - 947.3 1 2 0 -0.0004 13 0 0 0 3.91E+07 2.74E+07 - - - 6.2559 1 221125_WJC_METTL3_EV_vs_WT_F04.18240.18240.3 7.86E-08 17/56 R.LSFPSIK[136.11]PDTDQTLK[136.11].K "sp|Q92785|REQU_HUMAN,tr|J3KMZ8|J3KMZ8_HUMAN" 2 1704.9269 1.69 51756 18240 3 1704.928252 569.3162 Zinc finger protein ubi-d4 OS=Homo sapiens OX=9606 GN=DPF2 PE=1 SV=2 5.96 3091.1 - 927452 - - - 0.7918 - 2.821 0.534 - 229.2 1 2 0 0.0014 15 0 0 0 1.76E+07 1.04E+07 - - - 7.1993 0.9999 221125_WJC_METTL3_EV_vs_WT_F04.18241.18241.3 0.000107 14/48 R.SSGSHLVFVPSLR[166.11].D "sp|Q14181|DPOA2_HUMAN,tr|A0A3B3ITS5|A0A3B3ITS5_HUMAN,tr|H0YDR7|H0YDR7_HUMAN" 3 1394.7546 0.55 51757 18241 3 1394.753025 465.9255 DNA polymerase alpha subunit B OS=Homo sapiens OX=9606 GN=POLA2 PE=1 SV=2 9.49 3091.2 - 799100 - - - -1.107 - 2.717 0.346 - 258.7 1 2 0 -0.0015 13 0 0 0 2.97E+06 5.37E+06 - - - 5.1071 1 221125_WJC_METTL3_EV_vs_WT_F04.18242.18242.3 3.56E-12 22/84 K.VAALAASPASVAVDSGSELNSR.S sp|O15119|TBX3_HUMAN 1 2071.0546 0.88 51758 18242 3 2071.057492 691.3588 T-box transcription factor TBX3 OS=Homo sapiens OX=9606 GN=TBX3 PE=1 SV=4 4.37 3091.4 - 767049 - - - 1.4147 - 4.25 0.609 - 569.4 1 2 0 0.0029 22 0 0 0 3.95E+07 4.47E+07 - - - 8.7593 1 221125_WJC_METTL3_EV_vs_WT_F04.18248.18248.3 3.45E-07 Dec-40 K.ARPELEELLAK.L "sp|Q96GC5|RM48_HUMAN,tr|F5H702|F5H702_HUMAN,tr|F5H8D0|F5H8D0_HUMAN" 3 1267.7136 1.62 51764 18248 3 1267.713397 423.5785 "39S ribosomal protein L48, mitochondrial OS=Homo sapiens OX=9606 GN=MRPL48 PE=1 SV=2" 4.79 3092.1 - 390059 - - - -0.1617 - 2.44 0.448 - 293.3 1 2 0 -0.0002 11 0 0 0 2.58E+06 1.59E+06 - - - 6.0687 0.8962 221125_WJC_METTL3_EV_vs_WT_F04.18249.18249.3 0.596 Sep-56 R.LSC[160.03]SLC[160.03]PQYSVAVVR[166.11].S "sp|Q9H0K4|RSH6A_HUMAN,tr|M0R2K1|M0R2K1_HUMAN,tr|M0R103|M0R103_HUMAN" 3 1747.8625 12.44 51765 18249 3 1747.864026 583.6281 Radial spoke head protein 6 homolog A OS=Homo sapiens OX=9606 GN=RSPH6A PE=1 SV=1 8.06 3092.3 - 349521 - - - 0.8834 - 1.529 0.072 - 64.9 1 2 0 0.0015 15 0 0 0 3.95E+07 3.18E+06 - - - 0.4503 1 221125_WJC_METTL3_EV_vs_WT_F04.18250.18250.3 0.00202 15/48 R.SSGSHLVFVPSLR.D "sp|Q14181|DPOA2_HUMAN,tr|A0A3B3ITS5|A0A3B3ITS5_HUMAN,tr|H0YDR7|H0YDR7_HUMAN" 3 1384.7463 0.52 51766 18250 3 1384.743772 462.5894 DNA polymerase alpha subunit B OS=Homo sapiens OX=9606 GN=POLA2 PE=1 SV=2 9.49 3092.4 - 334931 - - - -1.8249 - 2.642 0.542 - 315.6 1 2 0 -0.0025 13 0 0 0 2.97E+06 5.69E+06 - - - 7.2162 0.9999 221125_WJC_METTL3_EV_vs_WT_F04.18251.18251.3 0.00947 Jul-36 K.RQDLLNVLAR.M sp|Q96A33|CCD47_HUMAN 1 1196.699 1.13 51767 18251 3 1196.698528 399.9069 PAT complex subunit CCDC47 OS=Homo sapiens OX=9606 GN=CCDC47 PE=1 SV=1 9.6 3092.5 - 290054 - - - -0.3568 - 1.851 0.404 - 64.7 1 2 0 -0.0004 10 0 0 0 2.70E+06 2.38E+06 - - - 4.8423 0.9999 221125_WJC_METTL3_EV_vs_WT_F04.18252.18252.4 0.000565 Dec-72 R.LYHLGLPSHDLLR.V "tr|A0A087WX24|A0A087WX24_HUMAN,tr|H7BY14|H7BY14_HUMAN,tr|A0A087WU74|A0A087WU74_HUMAN" 3 1532.8463 2.93 51768 18252 4 1532.845224 384.2189 Sterile alpha motif domain-containing protein 11 OS=Homo sapiens OX=9606 GN=SAMD11 PE=1 SV=2 6.92 3092.6 - 261617 - - - -0.7326 - 2.172 0.43 - 107.2 1 2 0 -0.0011 13 0 0 0 1.03E+06 3.51E+05 - - - 3.256 1 221125_WJC_METTL3_EV_vs_WT_F04.18253.18253.4 1.21E-06 15/90 K.SPIAPEELALVHNLR[166.11]K[136.11].M "sp|P51398|RT29_HUMAN,tr|V9GYA7|V9GYA7_HUMAN,tr|V9GYJ9|V9GYJ9_HUMAN,tr|V9GYW1|V9GYW1_HUMAN,tr|V9GZ03|V9GZ03_HUMAN,tr|V9GZ61|V9GZ61_HUMAN,tr|V9GYC9|V9GYC9_HUMAN,tr|V9GYL9|V9GYL9_HUMAN" 8 1804.0326 1.02 51769 18253 4 1804.03097 452.0154 "28S ribosomal protein S29, mitochondrial OS=Homo sapiens OX=9606 GN=DAP3 PE=1 SV=1" 6.48 3092.8 - 247280 - - - -0.8969 - 2.828 0.482 - 278.9 1 2 0 -0.0016 16 0 0 0 1.01E+06 9.86E+05 - - - 3.7871 1 221125_WJC_METTL3_EV_vs_WT_F04.18255.18255.3 1.22E-09 19/52 W.ELISNASDALDK[136.11]IR[166.11].Y "sp|Q58FF8|H90B2_HUMAN,sp|P08238|HS90B_HUMAN,sp|Q58FF6|H90B4_HUMAN,sp|Q58FF7|H90B3_HUMAN,sp|P14625|ENPL_HUMAN,tr|A0A7P0T917|A0A7P0T917_HUMAN,tr|A0A7P0Z405|A0A7P0Z405_HUMAN,tr|A0A7P0T823|A0A7P0T823_HUMAN,tr|A0A7P0TAE1|A0A7P0TAE1_HUMAN,tr|H0YIV0|H0YIV0_HUMAN,tr|A0A7P0T8R3|A0A7P0T8R3_HUMAN,tr|A0A7P0T885|A0A7P0T885_HUMAN,tr|A0A7P0TAY2|A0A7P0TAY2_HUMAN,tr|A0A087WT78|A0A087WT78_HUMAN,tr|F8W026|F8W026_HUMAN,tr|A0A7P0TBC2|A0A7P0TBC2_HUMAN,tr|A0A7P0TAT8|A0A7P0TAT8_HUMAN" 17 1561.8431 0.88 51770 18255 3 1561.842135 521.6216 Putative heat shock protein HSP 90-beta 2 OS=Homo sapiens OX=9606 GN=HSP90AB2P PE=1 SV=2 4.56 3093 - 9.94E+06 - - - -0.5897 - 3.755 0.597 - 638.8 1 1 1 -0.0009 14 0 0 0 4.08E+07 4.61E+07 - - - 8.7119 0.9996 221125_WJC_METTL3_EV_vs_WT_F04.18257.18257.3 0.00323 Oct-44 R.GREFSFEAWNAK.L "sp|P78347|GTF2I_HUMAN,tr|A0A494C1K3|A0A494C1K3_HUMAN" 2 1440.6786 1.36 51772 18257 3 1440.679887 481.2335 General transcription factor II-I OS=Homo sapiens OX=9606 GN=GTF2I PE=1 SV=2 6.14 3093.1 - 6.56E+06 - - - 0.8843 - 2.261 0.406 - 107.1 1 2 1 0.0013 12 0 0 0 3.26E+07 2.40E+07 - - - 5.3274 0.9999 221125_WJC_METTL3_EV_vs_WT_F04.18258.18258.3 4.25E-06 Dec-44 R.GR[166.11]EFSFEAWNAK[136.11].L "sp|P78347|GTF2I_HUMAN,tr|A0A494C1K3|A0A494C1K3_HUMAN" 2 1458.7011 1.36 51773 18258 3 1458.701281 487.241 General transcription factor II-I OS=Homo sapiens OX=9606 GN=GTF2I PE=1 SV=2 6.14 3093.1 - 4.25E+06 - - - 0.1357 - 2.447 0.523 - 185.5 1 2 1 0.0002 12 0 0 0 3.26E+07 2.40E+07 - - - 6.8513 0.9925 221125_WJC_METTL3_EV_vs_WT_F04.18259.18259.2 1.78E-08 28-Dec F.QYGPAVFPVAPTSSK.Q "sp|Q14157|UBP2L_HUMAN,tr|F8W726|F8W726_HUMAN,tr|H7C2T8|H7C2T8_HUMAN,tr|H0Y5H6|H0Y5H6_HUMAN" 4 1547.7984 2.15 51774 18259 2 1547.799366 774.9065 Ubiquitin-associated protein 2-like OS=Homo sapiens OX=9606 GN=UBAP2L PE=1 SV=2 8.59 3093.2 - 2.93E+06 - - - 0.628 - 2.408 0.516 - 401.2 1 1 0 0.001 15 0 0 0 1.77E+07 8.25E+06 - - - 5.0124 1 221125_WJC_METTL3_EV_vs_WT_F04.18261.18261.3 1.86E-05 18/68 K.LHIIEVGTPPTGNQPFPK[136.11].K "sp|Q00610|CLH1_HUMAN,tr|A0A087WVQ6|A0A087WVQ6_HUMAN" 2 1952.0611 1.12 51776 18261 3 1952.060774 651.6943 Clathrin heavy chain 1 OS=Homo sapiens OX=9606 GN=CLTC PE=1 SV=5 6.75 3093.3 - 2.06E+06 - - - -0.166 - 3.348 0.557 - 455.9 1 2 0 -0.0003 18 0 0 0 7.88E+07 7.04E+07 - - - 7.7589 1 221125_WJC_METTL3_EV_vs_WT_F04.18267.18267.2 6.80E-12 15/26 R.AHQVVEDGYEFFAK[136.11].R "sp|P62136|PP1A_HUMAN,sp|P62140|PP1B_HUMAN,sp|P36873|PP1G_HUMAN,tr|A0A7I2V4F7|A0A7I2V4F7_HUMAN,tr|F8W0W8|F8W0W8_HUMAN,tr|F8VYE8|F8VYE8_HUMAN,tr|E9PMD7|E9PMD7_HUMAN" 7 1646.782 1.36 51782 18267 2 1646.77926 824.3983 Serine\threonine-protein phosphatase PP1-alpha catalytic subunit OS=Homo sapiens OX=9606 GN=PPP1CA PE=1 SV=1 4.65 3094 - 998777 - - - -1.6772 - 3.029 0.642 - 549.4 1 2 0 -0.0028 14 0 0 0 4.39E+06 3.23E+06 - - - 6.563 0.962 221125_WJC_METTL3_EV_vs_WT_F04.18269.18269.3 3.06E-05 15/64 R.HVDAHATLNDGVVVQVM.G "sp|Q13283|G3BP1_HUMAN,tr|A0A7I2YQB1|A0A7I2YQB1_HUMAN,tr|A0A7I2V5M7|A0A7I2V5M7_HUMAN,tr|E5RH42|E5RH42_HUMAN,tr|A0A7P0P2U7|A0A7P0P2U7_HUMAN,tr|A0A7I2YQU8|A0A7I2YQU8_HUMAN,tr|E5RJU8|E5RJU8_HUMAN,tr|A0A7I2YQQ8|A0A7I2YQQ8_HUMAN,tr|A0A7I2V651|A0A7I2V651_HUMAN,tr|E5RIF8|E5RIF8_HUMAN,tr|A0A7I2YQN9|A0A7I2YQN9_HUMAN" 11 1803.8938 - 51784 18269 3 1803.896779 602.3052 Ras GTPase-activating protein-binding protein 1 OS=Homo sapiens OX=9606 GN=G3BP1 PE=1 SV=1 5.05 3094.2 - 749569 - - - 1.6692 - 2.716 0.301 - 199.6 1 1 0 0.003 17 0 0 0 - - - - - 4.4192 0.9994 221125_WJC_METTL3_EV_vs_WT_F04.18273.18273.3 0.0075 Sep-48 K.VIQYLAYVASSHK.S "sp|P35579|MYH9_HUMAN,tr|Q5BKV1|Q5BKV1_HUMAN" 2 1477.7929 0.21 51788 18273 3 1477.793267 493.6049 Myosin-9 OS=Homo sapiens OX=9606 GN=MYH9 PE=1 SV=4 8.48 3094.7 - 662405 - - - 0.2382 - 2.019 0.295 - 72.7 1 2 0 0.0004 13 0 0 0 3.02E+06 1.42E+07 - - - 3.7338 0.9999 221125_WJC_METTL3_EV_vs_WT_F04.18274.18274.3 5.46E-05 Oct-36 K.DVDDFFEHER[166.11].T "sp|Q9UNH7|SNX6_HUMAN,tr|A0A0A0MRI2|A0A0A0MRI2_HUMAN,tr|G3V5X9|G3V5X9_HUMAN" 3 1317.5501 1.78 51789 18274 3 1317.5486 440.1906 Sorting nexin-6 OS=Homo sapiens OX=9606 GN=SNX6 PE=1 SV=1 4.1 3094.8 - 618583 - - - -1.1499 - 1.718 0.491 - 109.4 1 2 0 -0.0015 10 0 0 0 9.41E+06 5.29E+06 - - - 5.5942 0.9969 221125_WJC_METTL3_EV_vs_WT_F04.18277.18277.3 0.000738 Oct-60 R.ELVFKEDGQEYAQVIK.M "sp|O14602|IF1AY_HUMAN,sp|P47813|IF1AX_HUMAN,tr|A6NJH9|A6NJH9_HUMAN" 3 1894.9676 0.69 51791 18277 3 1894.97082 632.6632 "Eukaryotic translation initiation factor 1A, Y-chromosomal OS=Homo sapiens OX=9606 GN=EIF1AY PE=1 SV=4" 4.41 3095.1 - 913296 - - - 1.676 - 2.323 0.291 - 103.5 1 2 1 0.0032 16 0 0 0 1.69E+08 2.44E+08 - - - 3.9461 0.9999 221125_WJC_METTL3_EV_vs_WT_F04.18279.18279.3 1.45E-06 14/44 R.YLYTLVITDK[136.11]EK[136.11].A "sp|P63173|RL38_HUMAN,tr|J3KT73|J3KT73_HUMAN,tr|J3QL01|J3QL01_HUMAN" 3 1500.841 1.27 51793 18279 3 1500.840571 501.2876 60S ribosomal protein L38 OS=Homo sapiens OX=9606 GN=RPL38 PE=1 SV=2 6.07 3095.2 - 4.31E+06 - - - -0.3172 - 2.506 0.54 - 174.3 1 2 1 -0.0005 12 0 0 0 7.06E+07 5.56E+07 - - - 7.1068 1 221125_WJC_METTL3_EV_vs_WT_F04.18280.18280.3 6.60E-06 13/44 R.K[136.11]SEIEYYAMLAK[136.11].T "sp|P62888|RL30_HUMAN,tr|E5RI99|E5RI99_HUMAN" 2 1460.7556 1.08 51794 18280 3 1460.755954 487.9258 60S ribosomal protein L30 OS=Homo sapiens OX=9606 GN=RPL30 PE=1 SV=2 6.14 3095.3 - 4.23E+06 - - - 0.2403 - 2.327 0.572 - 180.9 1 2 0 0.0004 12 0 0 0 1.97E+07 1.81E+07 - - - 7.2582 0.9996 221125_WJC_METTL3_EV_vs_WT_F04.18282.18282.3 5.06E-05 13/44 R.YLYTLVITDKEK.A "sp|P63173|RL38_HUMAN,tr|J3KT73|J3KT73_HUMAN,tr|J3QL01|J3QL01_HUMAN" 3 1484.8126 1.37 51796 18282 3 1484.812312 495.9448 60S ribosomal protein L38 OS=Homo sapiens OX=9606 GN=RPL38 PE=1 SV=2 6.07 3095.4 - 3.65E+06 - - - -0.2256 - 2.191 0.406 - 128 1 2 1 -0.0003 12 0 0 0 7.60E+07 5.56E+07 - - - 5.2405 1 221125_WJC_METTL3_EV_vs_WT_F04.18283.18283.3 0.000595 18/52 R.GPR[166.11]PWEDPDLLQGR[166.11].N "sp|Q9P0S2|COX16_HUMAN,tr|A0A087WX56|A0A087WX56_HUMAN,tr|A0A087X1F5|A0A087X1F5_HUMAN,tr|A0A087WYV9|A0A087WYV9_HUMAN" 4 1654.833 1.58 51797 18283 3 1654.834209 552.6183 "Cytochrome c oxidase assembly protein COX16 homolog, mitochondrial OS=Homo sapiens OX=9606 GN=COX16 PE=1 SV=1" 4.56 3095.4 - 2.86E+06 - - - 0.704 - 3.279 0.496 - 681.4 1 2 0 0.0012 14 0 0 0 9.40E+07 5.95E+07 - - - 7.2255 1 221125_WJC_METTL3_EV_vs_WT_F04.18286.18286.2 8.79E-08 15/22 R.K[136.11]SEIEYYAMLAK[136.11].T "sp|P62888|RL30_HUMAN,tr|E5RI99|E5RI99_HUMAN" 2 1460.7556 1.13 51800 18286 2 1460.75843 731.3851 60S ribosomal protein L30 OS=Homo sapiens OX=9606 GN=RPL30 PE=1 SV=2 6.14 3095.7 - 878575 - - - 1.9353 - 3.355 0.579 - 681.4 1 2 0 0.0028 12 0 0 0 4.18E+06 3.68E+06 - - - 6.5015 0.9992 221125_WJC_METTL3_EV_vs_WT_F04.18287.18287.3 0.000513 Oct-60 R.HVLEYNEER[166.11]DDFDLEA.- sp|Q9NV31|IMP3_HUMAN 1 2002.8784 -1 51801 18287 3 2002.878442 668.6334 U3 small nucleolar ribonucleoprotein protein IMP3 OS=Homo sapiens OX=9606 GN=IMP3 PE=1 SV=1 3.95 3095.9 - 684189 - - - 0.0285 - 1.761 0.418 - 72.5 1 2 1 0.0001 16 0 0 0 0.00E+00 0.00E+00 - - - 4.6522 0.9978 221125_WJC_METTL3_EV_vs_WT_F04.18288.18288.3 0.00628 Aug-48 R.ESQDTSFTTLVER.V "sp|Q06210|GFPT1_HUMAN,tr|A0A6I8PRN4|A0A6I8PRN4_HUMAN,tr|A0A6I8PTT9|A0A6I8PTT9_HUMAN" 3 1511.7104 0.32 51802 18288 3 1511.710735 504.9107 Glutamine--fructose-6-phosphate aminotransferase [isomerizing] 1 OS=Homo sapiens OX=9606 GN=GFPT1 PE=1 SV=3 4.14 3096 - 646451 - - - 0.2434 - 1.381 0.301 - 75.8 1 2 0 0.0004 13 0 0 0 5.33E+06 1.67E+07 - - - 2.771 0.9874 221125_WJC_METTL3_EV_vs_WT_F04.18291.18291.3 0.0112 Sep-44 K.SGYIESVQHILK.D "sp|Q9BQP7|MGME1_HUMAN,tr|Q5QPE8|Q5QPE8_HUMAN" 2 1372.7351 1.52 51805 18291 3 1372.731792 458.5856 Mitochondrial genome maintenance exonuclease 1 OS=Homo sapiens OX=9606 GN=MGME1 PE=1 SV=1 6.47 3096.3 - 448901 - - - -2.3843 - 1.378 0.248 - 60.2 1 2 0 -0.0033 12 0 0 0 2.00E+06 1.32E+06 - - - 2.1928 0.9785 221125_WJC_METTL3_EV_vs_WT_F04.18297.18297.3 0.000587 17/76 M.RILSAENIPNLPPGGGLAGK.R "sp|O75688|PPM1B_HUMAN,tr|B8ZZF0|B8ZZF0_HUMAN,tr|A0A3B3IS24|A0A3B3IS24_HUMAN,tr|C9JIR6|C9JIR6_HUMAN" 4 1973.1058 3.94 51810 18297 3 1973.107459 658.7092 Protein phosphatase 1B OS=Homo sapiens OX=9606 GN=PPM1B PE=1 SV=1 8.75 3097.1 - 2.63E+06 - - - 0.8357 - 2.882 0.309 - 256.3 1 1 0 0.0016 20 0 0 0 6.00E+07 1.52E+07 - - - 4.5525 0.9986 221125_WJC_METTL3_EV_vs_WT_F04.18298.18298.3 0.00943 Oct-44 K.SGYIESVQHILK[136.11].D "sp|Q9BQP7|MGME1_HUMAN,tr|Q5QPE8|Q5QPE8_HUMAN" 2 1380.7493 1.47 51811 18298 3 1380.751838 461.257 Mitochondrial genome maintenance exonuclease 1 OS=Homo sapiens OX=9606 GN=MGME1 PE=1 SV=1 6.47 3097.2 - 510373 - - - 1.8635 - 1.73 0.309 - 71.8 1 2 0 0.0026 12 0 0 0 1.94E+06 1.32E+06 - - - 3.5036 1 221125_WJC_METTL3_EV_vs_WT_F04.18300.18300.3 1.11E-05 15/68 K.LHIIEVGTPPTGNQPFPK.K "sp|Q00610|CLH1_HUMAN,tr|A0A087WVQ6|A0A087WVQ6_HUMAN" 2 1944.0469 1.12 51813 18300 3 1944.048333 649.0229 Clathrin heavy chain 1 OS=Homo sapiens OX=9606 GN=CLTC PE=1 SV=5 6.75 3097.3 - 3.86E+06 - - - 0.7382 - 2.873 0.539 - 329.2 1 2 0 0.0014 18 0 0 0 7.88E+07 7.04E+07 - - - 7.1769 1 221125_WJC_METTL3_EV_vs_WT_F04.18303.18303.2 5.52E-09 16/28 K.SLDIGNQMNVSEEMK.V "sp|Q6P3W7|SCYL2_HUMAN,tr|F8VSC5|F8VSC5_HUMAN,tr|A0A0U1RQQ9|A0A0U1RQQ9_HUMAN" 3 1693.7651 1.84 51816 18303 2 1693.765504 847.8898 SCY1-like protein 2 OS=Homo sapiens OX=9606 GN=SCYL2 PE=1 SV=1 4.14 3097.5 - 1.29E+06 - - - 0.2261 - 2.876 0.666 - 706 1 2 0 0.0004 15 0 0 0 9.98E+06 5.44E+06 - - - 6.5572 0.9888 221125_WJC_METTL3_EV_vs_WT_F04.18304.18304.3 0.0168 Aug-60 R.HVLEYNEERDDFDLEA.- sp|Q9NV31|IMP3_HUMAN 1 1992.8701 1.68 51817 18304 3 1992.870742 665.2973 U3 small nucleolar ribonucleoprotein protein IMP3 OS=Homo sapiens OX=9606 GN=IMP3 PE=1 SV=1 3.95 3097.6 - 1.12E+06 - - - 0.3146 - 1.376 0.299 - 61.7 1 2 1 0.0006 16 0 0 0 4.26E+06 2.53E+06 - - - 2.6924 1 221125_WJC_METTL3_EV_vs_WT_F04.18306.18306.3 0.000205 16/48 R.EAYPGDVFYLHSR.L sp|P25705|ATPA_HUMAN 1 1552.731 2.5 51819 18306 3 1552.732905 518.5843 "ATP synthase subunit alpha, mitochondrial OS=Homo sapiens OX=9606 GN=ATP5F1A PE=1 SV=1" 5.32 3097.8 - 980037 - - - 1.1992 - 2.592 0.484 - 272.1 1 2 0 0.0019 13 0 0 0 2.43E+07 9.72E+06 - - - 6.5179 0.9999 221125_WJC_METTL3_EV_vs_WT_F04.18307.18307.2 6.54E-06 24-Nov R.SSFESSC[160.03]PQQWIK[136.11].Y sp|Q5JTJ3|COA6_HUMAN 1 1590.7228 0.86 51820 18307 2 1590.722701 796.3687 Cytochrome c oxidase assembly factor 6 homolog OS=Homo sapiens OX=9606 GN=COA6 PE=1 SV=1 5.72 3098 - 977859 - - - -0.0578 - 2.236 0.591 - 216.3 1 2 0 -0.0001 13 0 0 0 3.31E+07 3.86E+07 - - - 5.4714 1 221125_WJC_METTL3_EV_vs_WT_F04.18308.18308.2 2.41E-09 16/28 K.SLDIGNQMNVSEEMK[136.11].V "sp|Q6P3W7|SCYL2_HUMAN,tr|F8VSC5|F8VSC5_HUMAN,tr|A0A0U1RQQ9|A0A0U1RQQ9_HUMAN" 3 1701.7793 1.84 51821 18308 2 1701.778367 851.8969 SCY1-like protein 2 OS=Homo sapiens OX=9606 GN=SCYL2 PE=1 SV=1 4.14 3098.1 - 782542 - - - -0.5606 - 3.091 0.627 - 765.3 1 2 0 -0.001 15 0 0 0 9.98E+06 5.44E+06 - - - 6.4462 0.9994 221125_WJC_METTL3_EV_vs_WT_F04.18309.18309.2 0.0011 24-Dec R.SSFESSC[160.03]PQQWIK.Y sp|Q5JTJ3|COA6_HUMAN 1 1582.7086 0.85 51822 18309 2 1582.703356 792.3616 Cytochrome c oxidase assembly factor 6 homolog OS=Homo sapiens OX=9606 GN=COA6 PE=1 SV=1 5.72 3098.2 - 718174 - - - -3.3089 - 2.504 0.505 - 341.5 1 2 0 -0.0052 13 0 0 0 3.26E+07 3.84E+07 - - - 5.1251 1 221125_WJC_METTL3_EV_vs_WT_F04.18312.18312.2 2.13E-07 19/42 K.VAALAASPASVAVDSGSELNSR.S sp|O15119|TBX3_HUMAN 1 2071.0546 1.17 51825 18312 2 2071.05599 1036.5346 T-box transcription factor TBX3 OS=Homo sapiens OX=9606 GN=TBX3 PE=1 SV=4 4.37 3098.6 - 618519 - - - 0.6895 - 3.78 0.589 - 636.5 1 2 0 0.0014 22 0 0 0 1.74E+07 1.49E+07 - - - 6.6601 0.9987 221125_WJC_METTL3_EV_vs_WT_F04.18314.18314.2 5.52E-06 22-Nov R.YLYTLVITDK[136.11]EK[136.11].A "sp|P63173|RL38_HUMAN,tr|J3KT73|J3KT73_HUMAN,tr|J3QL01|J3QL01_HUMAN" 3 1500.841 1.03 51827 18314 2 1500.841793 751.4278 60S ribosomal protein L38 OS=Homo sapiens OX=9606 GN=RPL38 PE=1 SV=2 6.07 3098.9 - 507206 - - - 0.4971 - 2.197 0.549 - 346 1 2 1 0.0007 12 0 0 0 4.56E+06 4.43E+06 - - - 5.1667 1 221125_WJC_METTL3_EV_vs_WT_F04.18315.18315.2 1.33E-08 15/22 R.YLYTLVITDKEK.A "sp|P63173|RL38_HUMAN,tr|J3KT73|J3KT73_HUMAN,tr|J3QL01|J3QL01_HUMAN" 3 1484.8126 1.03 51828 18315 2 1484.813005 743.4136 60S ribosomal protein L38 OS=Homo sapiens OX=9606 GN=RPL38 PE=1 SV=2 6.07 3099 - 466145 - - - 0.2411 - 2.901 0.607 - 756.4 1 2 1 0.0004 12 0 0 0 4.56E+06 4.43E+06 - - - 6.3265 0.9999 221125_WJC_METTL3_EV_vs_WT_F04.18316.18316.3 0.00444 13/48 K.GAIIQLATGELKR.V sp|P0C7T5|ATX1L_HUMAN 1 1368.8089 1.75 51829 18316 3 1368.810573 457.2769 Ataxin-1-like OS=Homo sapiens OX=9606 GN=ATXN1L PE=1 SV=1 8.75 3099.1 - 454481 - - - 1.223 - 2.633 0.429 - 323.1 1 2 0 0.0017 13 0 0 0 1.98E+06 1.13E+06 - - - 5.9473 1 221125_WJC_METTL3_EV_vs_WT_F04.18318.18318.3 4.73E-05 Dec-40 R.RNLDFQDVLDK.L sp|Q9Y3I0|RTCB_HUMAN 1 1361.6939 1.59 51830 18318 3 1361.691041 454.9053 RNA-splicing ligase RtcB homolog OS=Homo sapiens OX=9606 GN=RTCB PE=1 SV=1 4.43 3099.4 - 574304 - - - -2.1209 - 2.276 0.545 - 226.9 1 2 0 -0.0029 11 0 0 0 2.47E+06 1.56E+06 - - - 6.9518 0.9999 221125_WJC_METTL3_EV_vs_WT_F04.18321.18321.3 5.66E-06 14/64 K.LADFGVAGQLTDTQIKR.N "sp|Q9P289|STK26_HUMAN,sp|O00506|STK25_HUMAN,sp|Q9Y6E0|STK24_HUMAN,tr|C9JDH9|C9JDH9_HUMAN,tr|C9J232|C9J232_HUMAN,tr|B4E0Y9|B4E0Y9_HUMAN,tr|B4DR80|B4DR80_HUMAN,tr|C9JJV0|C9JJV0_HUMAN,tr|Q8NBY1|Q8NBY1_HUMAN,tr|H7C279|H7C279_HUMAN,tr|C9JCC0|C9JCC0_HUMAN,tr|H0Y630|H0Y630_HUMAN,tr|C9J6L2|C9J6L2_HUMAN" 13 1831.9792 0.94 51833 18321 3 1831.983103 611.667 Serine\threonine-protein kinase 26 OS=Homo sapiens OX=9606 GN=STK26 PE=1 SV=2 5.96 3099.6 - 1.08E+06 - - - 2.1239 - 2.729 0.501 - 240.6 1 2 0 0.0039 17 0 0 0 1.53E+07 1.62E+07 - - - 6.6608 0.8469 221125_WJC_METTL3_EV_vs_WT_F04.18322.18322.3 0.525 13/76 M.R[166.11]ILSAENIPNLPPGGGLAGK[136.11].R "sp|O75688|PPM1B_HUMAN,tr|B8ZZF0|B8ZZF0_HUMAN,tr|A0A3B3IS24|A0A3B3IS24_HUMAN,tr|C9JIR6|C9JIR6_HUMAN" 4 1991.1283 3.94 51834 18322 3 1991.126737 664.7167 Protein phosphatase 1B OS=Homo sapiens OX=9606 GN=PPM1B PE=1 SV=1 8.75 3099.8 - 895198 - - - -0.7749 - 2.146 0.228 - 134.4 1 1 0 -0.0015 20 0 0 0 6.00E+07 1.52E+07 - - - 2.9341 0.9995 221125_WJC_METTL3_EV_vs_WT_F04.18323.18323.2 8.78E-06 26-Oct R.GPRPWEDPDLLQGR.N "sp|Q9P0S2|COX16_HUMAN,tr|A0A087WX56|A0A087WX56_HUMAN,tr|A0A087X1F5|A0A087X1F5_HUMAN,tr|A0A087WYV9|A0A087WYV9_HUMAN" 4 1634.8165 0.07 51835 18323 2 1634.820659 818.4155 "Cytochrome c oxidase assembly protein COX16 homolog, mitochondrial OS=Homo sapiens OX=9606 GN=COX16 PE=1 SV=1" 4.56 3099.9 - 549897 - - - 2.5416 - 1.882 0.536 - 149.1 1 2 0 0.0042 14 0 0 0 4.84E+06 6.93E+07 - - - 4.5854 1 221125_WJC_METTL3_EV_vs_WT_F04.18326.18326.2 1.23E-09 16/42 K.VAALAASPASVAVDSGSELNSR[166.11].S sp|O15119|TBX3_HUMAN 1 2081.0628 1.18 51838 18326 2 2082.056765 1041.5387 T-box transcription factor TBX3 OS=Homo sapiens OX=9606 GN=TBX3 PE=1 SV=4 4.37 3100.3 - 531299 - - - 477.6084 - 3.419 0.572 - 431.9 1 2 0 0.9939 22 0 0 0 1.57E+07 1.33E+07 - - - 5.9761 1 221125_WJC_METTL3_EV_vs_WT_F04.18330.18330.2 1.07E-08 28-Dec K.DFMVQGGDFSEGNGR[166.11].G "sp|Q13427|PPIG_HUMAN,tr|A0A7I2V629|A0A7I2V629_HUMAN,tr|C9JM79|C9JM79_HUMAN,tr|C9JN15|C9JN15_HUMAN,tr|A0A7I2V5Q5|A0A7I2V5Q5_HUMAN,tr|A0A7I2V4W3|A0A7I2V4W3_HUMAN" 6 1624.6815 1.5 51842 18330 2 1624.678608 813.348 Peptidyl-prolyl cis-trans isomerase G OS=Homo sapiens OX=9606 GN=PPIG PE=1 SV=2 4.03 3100.8 - 395419 - - - -1.8047 - 2.448 0.682 - 344.7 1 2 0 -0.0029 15 0 0 0 3.42E+06 2.28E+06 - - - 6.2784 1 221125_WJC_METTL3_EV_vs_WT_F04.18340.18340.2 6.37E-09 17/34 K.PSTASAVPELATDPELEK[136.11].K "sp|Q86U44|MTA70_HUMAN,tr|B4E349|B4E349_HUMAN,tr|F5H6D8|F5H6D8_HUMAN,tr|H0YFV6|H0YFV6_HUMAN,tr|B4DTN4|B4DTN4_HUMAN" 5 1861.94 0.02 51850 18340 2 1861.938124 931.9773 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 4 3102 - 1.63E+06 - - - -1.0285 - 3.358 0.585 - 521.3 1 1 0 -0.0019 18 0 0 0 1.27E+07 5.29E+08 - - - 6.3394 0.9999 221125_WJC_METTL3_EV_vs_WT_F04.18342.18342.4 4.22E-09 25/108 R.IHYIGQNEPELLVAHAYTR.Y "sp|P30519|HMOX2_HUMAN,tr|I3L159|I3L159_HUMAN,tr|A0A087WT44|A0A087WT44_HUMAN,tr|I3L1F5|I3L1F5_HUMAN" 4 2223.1437 1.64 51852 18342 4 2223.147254 556.7932 Heme oxygenase 2 OS=Homo sapiens OX=9606 GN=HMOX2 PE=1 SV=2 6 3102.2 - 1.28E+06 - - - 1.6202 - 4.1 0.449 - 709.2 1 2 0 0.0036 19 0 0 0 1.15E+07 7.03E+06 - - - 3.6104 1 221125_WJC_METTL3_EV_vs_WT_F04.18344.18344.4 2.38E-07 22/108 R.IHYIGQNEPELLVAHAYTR[166.11].Y "sp|P30519|HMOX2_HUMAN,tr|I3L159|I3L159_HUMAN,tr|A0A087WT44|A0A087WT44_HUMAN,tr|I3L1F5|I3L1F5_HUMAN" 4 2233.1519 1.62 51854 18344 4 2233.152963 559.2953 Heme oxygenase 2 OS=Homo sapiens OX=9606 GN=HMOX2 PE=1 SV=2 6 3102.4 - 1.12E+06 - - - 0.4662 - 4.053 0.554 - 450.1 1 2 0 0.001 19 0 0 0 1.14E+07 7.03E+06 - - - 4.5211 1 221125_WJC_METTL3_EV_vs_WT_F04.18348.18348.2 2.62E-09 19/30 R.TVEEEDQIFLDGQENK.R "sp|Q96HA1|P121A_HUMAN,sp|A8CG34|P121C_HUMAN,sp|Q6PJE2|POZP3_HUMAN,tr|A0A0J9YWR1|A0A0J9YWR1_HUMAN,tr|C9J370|C9J370_HUMAN,tr|C9JER0|C9JER0_HUMAN" 6 1892.864 1.97 51858 18348 2 1892.863908 947.4393 Nuclear envelope pore membrane protein POM 121 OS=Homo sapiens OX=9606 GN=POM121 PE=1 SV=2 3.77 3102.9 - 860787 - - - -0.0312 - 3.565 0.684 - 1018.1 1 2 0 -0.0001 16 0 0 0 9.97E+06 5.06E+06 - - - 7.2182 0.9998 221125_WJC_METTL3_EV_vs_WT_F04.18350.18350.2 2.05E-07 28-Nov K.DFMVQGGDFSEGNGR.G "sp|Q13427|PPIG_HUMAN,tr|A0A7I2V629|A0A7I2V629_HUMAN,tr|C9JM79|C9JM79_HUMAN,tr|C9JN15|C9JN15_HUMAN,tr|A0A7I2V5Q5|A0A7I2V5Q5_HUMAN,tr|A0A7I2V4W3|A0A7I2V4W3_HUMAN" 6 1614.6733 1.5 51860 18350 2 1614.670023 808.3439 Peptidyl-prolyl cis-trans isomerase G OS=Homo sapiens OX=9606 GN=PPIG PE=1 SV=2 4.03 3103.2 - 397324 - - - -2.0109 - 2.151 0.648 - 260.7 1 2 0 -0.0032 15 0 0 0 3.42E+06 2.28E+06 - - - 5.7092 0.9999 221125_WJC_METTL3_EV_vs_WT_F04.18351.18351.2 4.40E-09 28-Nov K.EEISATQIIVC[160.03]TPEK.W "sp|O75643|U520_HUMAN,tr|A0A494C1A5|A0A494C1A5_HUMAN" 2 1716.8604 3.51 51861 18351 2 1716.858181 859.4375 U5 small nuclear ribonucleoprotein 200 kDa helicase OS=Homo sapiens OX=9606 GN=SNRNP200 PE=1 SV=2 4.25 3103.3 - 384896 - - - -1.2936 - 2.439 0.604 - 356.2 1 2 0 -0.0022 15 0 0 0 2.87E+06 8.17E+05 - - - 5.6935 0.9997 221125_WJC_METTL3_EV_vs_WT_F04.18355.18355.2 1.35E-05 13/24 R.QVQSLTC[160.03]EVDALK[136.11].G "sp|P08670|VIME_HUMAN,tr|B0YJC5|B0YJC5_HUMAN,tr|B0YJC4|B0YJC4_HUMAN" 3 1497.7588 2.12 51863 18355 2 1497.75655 749.8867 Vimentin OS=Homo sapiens OX=9606 GN=VIM PE=1 SV=4 4.37 3103.8 - 3.98E+06 - - - -1.5316 - 2.476 0.362 - 571.3 1 2 0 -0.0023 13 0 0 0 2.18E+08 1.03E+08 - - - 4.0409 1 221125_WJC_METTL3_EV_vs_WT_F04.18356.18356.3 1.21E-09 18/84 K.VAALAASPASVAVDSGSELNSR[166.11].S sp|O15119|TBX3_HUMAN 1 2081.0628 0.84 51864 18356 3 2081.060577 694.6949 T-box transcription factor TBX3 OS=Homo sapiens OX=9606 GN=TBX3 PE=1 SV=4 4.37 3103.8 - 3.38E+06 - - - -1.0836 - 3.859 0.625 - 391.3 1 2 0 -0.0023 22 0 0 0 3.95E+07 4.72E+07 - - - 8.7091 1 221125_WJC_METTL3_EV_vs_WT_F04.18358.18358.2 1.54E-08 16/30 K.SDGGYTYDTSDLAAIK.Q sp|P54136|SYRC_HUMAN 1 1675.7577 1.06 51866 18358 2 1675.75599 838.8861 "Arginine--tRNA ligase, cytoplasmic OS=Homo sapiens OX=9606 GN=RARS1 PE=1 SV=2" 3.93 3104.1 - 1.90E+06 - - - -1.027 - 3.553 0.68 - 764.6 1 2 0 -0.0017 16 0 0 0 5.34E+07 5.05E+07 - - - 7.1799 1 221125_WJC_METTL3_EV_vs_WT_F04.18359.18359.3 1.36E-06 17/56 R.DLSHIGDAVVISC[160.03]AK[136.11].D sp|P12004|PCNA_HUMAN 1 1591.8119 1.07 51867 18359 3 1591.810276 531.6113 Proliferating cell nuclear antigen OS=Homo sapiens OX=9606 GN=PCNA PE=1 SV=1 5.21 3104.2 - 1.76E+06 - - - -1.0466 - 3.019 0.463 - 429.8 1 2 0 -0.0017 15 0 0 0 2.26E+07 2.11E+07 - - - 6.5847 1 221125_WJC_METTL3_EV_vs_WT_F04.18360.18360.3 1.73E-05 13/68 K.LLLNVTPTVRPDADQMTK.L "sp|Q6P3W7|SCYL2_HUMAN,tr|F8VSC5|F8VSC5_HUMAN,tr|A0A0U1RQQ9|A0A0U1RQQ9_HUMAN" 3 2011.0772 1.95 51868 18360 3 2011.07958 671.3663 SCY1-like protein 2 OS=Homo sapiens OX=9606 GN=SCYL2 PE=1 SV=1 5.96 3104.3 - 1.55E+06 - - - 1.1775 - 2.889 0.5 - 146.2 1 2 0 0.0024 18 0 0 0 3.81E+07 1.95E+07 - - - 6.7556 1 221125_WJC_METTL3_EV_vs_WT_F04.18361.18361.2 1.46E-11 17/30 K.SDGGYTYDTSDLAAIK[136.11].Q sp|P54136|SYRC_HUMAN 1 1683.7719 1.06 51869 18361 2 1683.771127 842.8932 "Arginine--tRNA ligase, cytoplasmic OS=Homo sapiens OX=9606 GN=RARS1 PE=1 SV=2" 3.93 3104.4 - 1.40E+06 - - - -0.4656 - 3.685 0.706 - 988.3 1 2 0 -0.0008 16 0 0 0 5.34E+07 5.05E+07 - - - 7.4619 1 221125_WJC_METTL3_EV_vs_WT_F04.18362.18362.2 2.25E-07 14/24 K.LFIGGLNTETNEK.A "sp|Q96E39|RMXL1_HUMAN,sp|P38159|RBMX_HUMAN,tr|A0A1B0GUK8|A0A1B0GUK8_HUMAN,tr|H3BT71|H3BT71_HUMAN,tr|H0Y6E7|H0Y6E7_HUMAN,tr|H3BR27|H3BR27_HUMAN,tr|H3BNC1|H3BNC1_HUMAN" 7 1434.7355 1.83 51870 18362 2 1434.733848 718.375 "RNA binding motif protein, X-linked-like-1 OS=Homo sapiens OX=9606 GN=RBMXL1 PE=1 SV=1" 4.53 3104.6 - 1.37E+06 - - - -1.1229 - 2.649 0.607 - 517.2 1 2 0 -0.0016 13 0 0 0 2.51E+07 1.37E+07 - - - 6.0241 1 221125_WJC_METTL3_EV_vs_WT_F04.18367.18367.3 1.60E-07 18/52 R.GPRPWEDPDLLQGR.N "sp|Q9P0S2|COX16_HUMAN,tr|A0A087WX56|A0A087WX56_HUMAN,tr|A0A087X1F5|A0A087X1F5_HUMAN,tr|A0A087WYV9|A0A087WYV9_HUMAN" 4 1634.8165 1.61 51873 18367 3 1634.814531 545.9461 "Cytochrome c oxidase assembly protein COX16 homolog, mitochondrial OS=Homo sapiens OX=9606 GN=COX16 PE=1 SV=1" 4.56 3105.1 - 4.75E+06 - - - -1.2069 - 3.185 0.587 - 712.6 1 2 0 -0.002 14 0 0 0 9.31E+07 5.78E+07 - - - 8.1625 0.9999 221125_WJC_METTL3_EV_vs_WT_F04.18368.18368.3 0.000107 13/56 R.GQMQKPFEDASFALR.T "sp|Q13526|PIN1_HUMAN,tr|K7EN45|K7EN45_HUMAN" 2 1723.8352 1.5 51874 18368 3 1723.833021 575.619 Peptidyl-prolyl cis-trans isomerase NIMA-interacting 1 OS=Homo sapiens OX=9606 GN=PIN1 PE=1 SV=1 6.07 3105.1 - 2.94E+06 - - - -1.2582 - 2.077 0.415 - 136.7 1 2 0 -0.0022 15 0 0 0 2.35E+07 1.56E+07 - - - 5.0735 1 221125_WJC_METTL3_EV_vs_WT_F04.18369.18369.3 2.75E-06 16/56 R.DLSHIGDAVVISC[160.03]AK.D sp|P12004|PCNA_HUMAN 1 1583.7977 1.07 51875 18369 3 1583.795855 528.9399 Proliferating cell nuclear antigen OS=Homo sapiens OX=9606 GN=PCNA PE=1 SV=1 5.21 3105.2 - 2.01E+06 - - - -1.1914 - 3.041 0.542 - 398.3 1 2 0 -0.0019 15 0 0 0 2.26E+07 2.11E+07 - - - 7.4843 1 221125_WJC_METTL3_EV_vs_WT_F04.18378.18378.2 2.45E-09 19/36 R.AAVDAGFVPNDMQVGQTGK.L "sp|P13804|ETFA_HUMAN,tr|H0YK49|H0YK49_HUMAN,tr|H0YL12|H0YL12_HUMAN,tr|H0YLU7|H0YLU7_HUMAN,tr|H0YNX6|H0YNX6_HUMAN" 5 1903.9098 3.59 51881 18378 2 1903.907054 952.9622 "Electron transfer flavoprotein subunit alpha, mitochondrial OS=Homo sapiens OX=9606 GN=ETFA PE=1 SV=1" 4.21 3106.3 - 2.31E+06 - - - -1.4486 - 3.889 0.659 - 641.5 1 2 0 -0.0028 19 0 0 0 2.00E+07 5.58E+06 - - - 7.2466 0.9995 221125_WJC_METTL3_EV_vs_WT_F04.18379.18379.3 2.77E-08 21/52 R.VDEIIWVK[136.11]TNQLQR[166.11].L sp|Q86U44|MTA70_HUMAN 1 1758.9747 0.59 51882 18379 3 1758.968412 587.3322 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 6.04 3106.4 - 1.93E+06 - - - -3.597 - 3.421 0.488 - 789.1 1 2 1 -0.0063 14 0 0 0 1.17E+07 1.99E+07 - - - 7.2476 0.9999 221125_WJC_METTL3_EV_vs_WT_F04.18380.18380.3 0.000121 Dec-48 R.AGHLC[160.03]TVQFLISK.G "sp|Q8IWZ3|ANKH1_HUMAN,tr|E9PDP5|E9PDP5_HUMAN,tr|H3BLS9|H3BLS9_HUMAN,tr|H7C2F5|H7C2F5_HUMAN" 4 1472.781 0.56 51883 18380 3 1472.781924 491.9343 Ankyrin repeat and KH domain-containing protein 1 OS=Homo sapiens OX=9606 GN=ANKHD1 PE=1 SV=1 8.27 3106.6 - 1.19E+06 - - - 0.6478 - 2.448 0.396 - 254.4 1 2 0 0.001 13 0 0 0 2.13E+07 3.77E+07 - - - 5.3821 1 221125_WJC_METTL3_EV_vs_WT_F04.18381.18381.2 1.61E-09 15/30 R.TEPTAQQNLALQLAEK.L "sp|Q99613|EIF3C_HUMAN,sp|B5ME19|EIFCL_HUMAN" 2 1753.921 1.29 51884 18381 2 1753.917168 877.9678 Eukaryotic translation initiation factor 3 subunit C OS=Homo sapiens OX=9606 GN=EIF3C PE=1 SV=1 4.53 3106.7 - 832332 - - - -2.2008 - 3.279 0.599 - 715.3 1 2 0 -0.0039 16 0 0 0 2.65E+07 2.06E+07 - - - 6.3836 1 221125_WJC_METTL3_EV_vs_WT_F04.18382.18382.2 2.23E-10 18/28 A.TIENAQPILQIDNAR.L sp|P08779|K1C16_HUMAN 1 1694.8951 999 51885 18382 2 1694.893252 848.4549 "Keratin, type I cytoskeletal 16 OS=Homo sapiens OX=9606 GN=KRT16 PE=1 SV=4" 4.37 3106.8 - 790086 - - - -1.1187 - 3.387 0.657 - 727.1 1 1 0 -0.0019 15 0 0 0 1.57E+07 0.00E+00 - - - 6.8923 0.9951 221125_WJC_METTL3_EV_vs_WT_F04.18383.18383.3 0.0764 13/44 K.QKVDSLLENLEK.L "sp|P0DMR1|HNRC4_HUMAN,sp|P07910|HNRPC_HUMAN,sp|O60812|HNRC1_HUMAN,sp|B2RXH8|HNRC2_HUMAN,sp|B7ZW38|HNRC3_HUMAN,tr|B4DY08|B4DY08_HUMAN,tr|G3V5V7|G3V5V7_HUMAN,tr|B2R5W2|B2R5W2_HUMAN,tr|G3V4C1|G3V4C1_HUMAN,tr|A0A0G2JPF8|A0A0G2JPF8_HUMAN,tr|A0A0G2JNQ3|A0A0G2JNQ3_HUMAN,tr|G3V576|G3V576_HUMAN,tr|G3V2D6|G3V2D6_HUMAN,tr|G3V4W0|G3V4W0_HUMAN,tr|G3V2Q1|G3V2Q1_HUMAN" 15 1414.7668 1.53 51886 18383 3 1414.766207 472.5962 Heterogeneous nuclear ribonucleoprotein C-like 4 OS=Homo sapiens OX=9606 GN=HNRNPCL4 PE=3 SV=1 4.68 3107 - 772896 - - - -0.3909 - 2.35 0.211 - 302.2 1 2 1 -0.0006 12 0 0 0 6.46E+07 4.21E+07 - - - 3.2606 1 221125_WJC_METTL3_EV_vs_WT_F04.18389.18389.3 1.91E-06 16/68 K.LLLNVTPTVR[166.11]PDADQMTK[136.11].L "sp|Q6P3W7|SCYL2_HUMAN,tr|F8VSC5|F8VSC5_HUMAN,tr|A0A0U1RQQ9|A0A0U1RQQ9_HUMAN" 3 2029.0997 1.95 51890 18389 3 2029.098737 677.3738 SCY1-like protein 2 OS=Homo sapiens OX=9606 GN=SCYL2 PE=1 SV=1 5.96 3107.8 - 1.63E+06 - - - -0.4657 - 3.13 0.471 - 277.8 1 2 0 -0.0009 18 0 0 0 3.81E+07 1.95E+07 - - - 6.6322 1 221125_WJC_METTL3_EV_vs_WT_F04.18390.18390.3 1.03E-05 Nov-48 R.ADHDFVVQEDFMK[136.11].A "sp|P62333|PRS10_HUMAN,tr|A0A087X2I1|A0A087X2I1_HUMAN" 2 1587.7119 0.4 51891 18390 3 1587.709405 530.2446 26S proteasome regulatory subunit 10B OS=Homo sapiens OX=9606 GN=PSMC6 PE=1 SV=1 4.22 3107.8 - 2.78E+06 - - - -1.5677 - 2.25 0.516 - 196.5 1 2 0 -0.0025 13 0 0 0 1.14E+07 2.88E+07 - - - 6.4909 0.9749 221125_WJC_METTL3_EV_vs_WT_F04.18391.18391.3 0.0542 Nov-44 K.QK[136.11]VDSLLENLEK[136.11].L "sp|P0DMR1|HNRC4_HUMAN,sp|P07910|HNRPC_HUMAN,sp|O60812|HNRC1_HUMAN,sp|B2RXH8|HNRC2_HUMAN,sp|B7ZW38|HNRC3_HUMAN,tr|B4DY08|B4DY08_HUMAN,tr|G3V5V7|G3V5V7_HUMAN,tr|B2R5W2|B2R5W2_HUMAN,tr|G3V4C1|G3V4C1_HUMAN,tr|A0A0G2JPF8|A0A0G2JPF8_HUMAN,tr|A0A0G2JNQ3|A0A0G2JNQ3_HUMAN,tr|G3V576|G3V576_HUMAN,tr|G3V2D6|G3V2D6_HUMAN,tr|G3V4W0|G3V4W0_HUMAN,tr|G3V2Q1|G3V2Q1_HUMAN" 15 1430.7952 1.53 51892 18391 3 1430.792484 477.939 Heterogeneous nuclear ribonucleoprotein C-like 4 OS=Homo sapiens OX=9606 GN=HNRNPCL4 PE=3 SV=1 4.68 3107.9 - 2.51E+06 - - - -1.8703 - 2.062 0.174 - 247.4 1 2 1 -0.0027 12 0 0 0 6.46E+07 4.21E+07 - - - 2.4851 0.9999 221125_WJC_METTL3_EV_vs_WT_F04.18392.18392.3 4.69E-07 16/60 K.SAIDLTPIVVEDKEEK.K "sp|Q14839|CHD4_HUMAN,tr|A0A2R8Y4X2|A0A2R8Y4X2_HUMAN,tr|A0A2U3TZM0|A0A2U3TZM0_HUMAN,tr|A0A2R8Y5M9|A0A2R8Y5M9_HUMAN,tr|A0A2R8YD40|A0A2R8YD40_HUMAN,tr|A0A2R8Y5J0|A0A2R8Y5J0_HUMAN,tr|A0A2R8Y425|A0A2R8Y425_HUMAN,tr|A0A2R8YFK9|A0A2R8YFK9_HUMAN,tr|A0A0C4DGG9|A0A0C4DGG9_HUMAN,tr|A0A2R8YFD8|A0A2R8YFD8_HUMAN,tr|A0A2R8YDW2|A0A2R8YDW2_HUMAN,tr|A0A2R8Y7I0|A0A2R8Y7I0_HUMAN,tr|F5GWX5|F5GWX5_HUMAN,tr|A0A2R8Y7X1|A0A2R8Y7X1_HUMAN,tr|A0A2R8Y7M9|A0A2R8Y7M9_HUMAN,tr|A0A2R8Y521|A0A2R8Y521_HUMAN,tr|A0A2R8YDJ9|A0A2R8YDJ9_HUMAN,tr|A0A2R8Y212|A0A2R8Y212_HUMAN,tr|A0A2R8YE38|A0A2R8YE38_HUMAN" 19 1784.9408 0.77 51893 18392 3 1784.941228 595.9875 Chromodomain-helicase-DNA-binding protein 4 OS=Homo sapiens OX=9606 GN=CHD4 PE=1 SV=2 4.18 3108 - 1.61E+06 - - - 0.2616 - 2.955 0.482 - 273.5 1 2 1 0.0005 16 0 0 0 1.59E+07 2.06E+07 - - - 6.6938 1 221125_WJC_METTL3_EV_vs_WT_F04.18393.18393.3 4.13E-08 17/52 K.FLQEFYQDDELGK[136.11]K[136.11].Q sp|P33993|MCM7_HUMAN 1 1774.8749 0.99 51894 18393 3 1774.875617 592.6322 DNA replication licensing factor MCM7 OS=Homo sapiens OX=9606 GN=MCM7 PE=1 SV=4 4.32 3108.1 - 1.23E+06 - - - 0.4226 - 2.647 0.599 - 323.1 1 2 0 0.0008 14 0 0 0 1.81E+07 1.84E+07 - - - 7.805 1 221125_WJC_METTL3_EV_vs_WT_F04.18394.18394.3 2.75E-08 16/48 R.QVQSLTC[160.03]EVDALK.G "sp|P08670|VIME_HUMAN,tr|B0YJC5|B0YJC5_HUMAN,tr|B0YJC4|B0YJC4_HUMAN" 3 1489.7446 2.38 51895 18394 3 1489.741287 497.5888 Vimentin OS=Homo sapiens OX=9606 GN=VIM PE=1 SV=4 4.37 3108.3 - 1.23E+06 - - - -2.2534 - 2.98 0.578 - 550.7 1 2 0 -0.0034 13 0 0 0 1.57E+07 6.58E+06 - - - 7.9437 1 221125_WJC_METTL3_EV_vs_WT_F04.18395.18395.2 1.59E-11 19/30 R.TEPTAQQNLALQLAEK[136.11].L "sp|Q99613|EIF3C_HUMAN,sp|B5ME19|EIFCL_HUMAN" 2 1761.9352 1.29 51896 18395 2 1761.926299 881.9749 Eukaryotic translation initiation factor 3 subunit C OS=Homo sapiens OX=9606 GN=EIF3C PE=1 SV=1 4.53 3108.4 - 1.16E+06 - - - -5.0677 - 3.652 0.652 - 1597.5 1 2 0 -0.0089 16 0 0 0 2.65E+07 2.06E+07 - - - 7.0384 1 221125_WJC_METTL3_EV_vs_WT_F04.18400.18400.3 1.48E-07 13/52 K.HINMDGTINVDDFK.L "sp|O75643|U520_HUMAN,tr|A0A494C1A5|A0A494C1A5_HUMAN" 2 1617.7457 2.09 51899 18400 3 1617.742549 540.2558 U5 small nuclear ribonucleoprotein 200 kDa helicase OS=Homo sapiens OX=9606 GN=SNRNP200 PE=1 SV=2 4.41 3109 - 3.33E+06 - - - -1.9521 - 2.612 0.619 - 368.6 1 2 0 -0.0032 14 0 0 0 4.01E+07 1.92E+07 - - - 7.9919 0.9999 221125_WJC_METTL3_EV_vs_WT_F04.18401.18401.3 4.26E-08 16/68 R.QISR[166.11]PSAAGINLMIGSTR[166.11].Y sp|Q08211|DHX9_HUMAN 1 1891.0213 0.57 51900 18401 3 1891.016379 631.3477 ATP-dependent RNA helicase A OS=Homo sapiens OX=9606 GN=DHX9 PE=1 SV=4 12 3109 - 5.85E+06 - - - -2.5785 - 2.832 0.533 - 279.2 1 2 0 -0.0049 18 0 0 0 4.24E+07 7.44E+07 - - - 7.0732 1 221125_WJC_METTL3_EV_vs_WT_F04.18402.18402.3 2.91E-08 19/60 R.TEPTAQQNLALQLAEK.L "sp|Q99613|EIF3C_HUMAN,sp|B5ME19|EIFCL_HUMAN" 2 1753.921 1.55 51901 18402 3 1753.92266 585.6476 Eukaryotic translation initiation factor 3 subunit C OS=Homo sapiens OX=9606 GN=EIF3C PE=1 SV=1 4.53 3109.1 - 2.12E+06 - - - 0.9305 - 2.673 0.491 - 501 1 2 0 0.0016 16 0 0 0 2.56E+07 1.65E+07 - - - 6.5365 0.9926 221125_WJC_METTL3_EV_vs_WT_F04.18404.18404.3 1.29E-05 15/52 K.DHTPSQELALTQSV.G "sp|Q86U44|MTA70_HUMAN,tr|H0YFV6|H0YFV6_HUMAN" 2 1524.742 - 51903 18404 3 1524.737063 509.2546 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 4.35 3109.3 - 1.57E+06 - - - -3.2386 - 2.852 0.547 - 274.1 1 1 0 -0.0049 14 0 0 0 - - - - - 7.4223 1 221125_WJC_METTL3_EV_vs_WT_F04.18405.18405.3 4.20E-06 14/52 K.HINMDGTINVDDFK[136.11].L "sp|O75643|U520_HUMAN,tr|A0A494C1A5|A0A494C1A5_HUMAN" 2 1625.7599 2.09 51904 18405 3 1625.761093 542.9272 U5 small nuclear ribonucleoprotein 200 kDa helicase OS=Homo sapiens OX=9606 GN=SNRNP200 PE=1 SV=2 4.41 3109.4 - 1.49E+06 - - - 0.7295 - 2.647 0.543 - 330.6 1 2 0 0.0012 14 0 0 0 4.01E+07 1.92E+07 - - - 7.1805 0.9991 221125_WJC_METTL3_EV_vs_WT_F04.18406.18406.2 0.000133 22-Dec K.DSGSQEVLSELR[166.11].V "sp|Q9BVJ6|UT14A_HUMAN,tr|X6RJY0|X6RJY0_HUMAN" 2 1328.6447 1.66 51905 18406 2 1328.639292 665.3296 U3 small nucleolar RNA-associated protein 14 homolog A OS=Homo sapiens OX=9606 GN=UTP14A PE=1 SV=1 4.14 3109.5 - 1.35E+06 - - - -4.1034 - 2.74 0.5 - 675.2 1 2 0 -0.0055 12 0 0 0 2.88E+07 1.73E+07 - - - 5.3844 1 221125_WJC_METTL3_EV_vs_WT_F04.18407.18407.3 0.00622 15/52 R.RLQLSPWESSVVNR.L "sp|Q14244|MAP7_HUMAN,tr|A0A087WZ40|A0A087WZ40_HUMAN" 2 1669.89 999 51906 18407 3 1669.891395 557.6373 Ensconsin OS=Homo sapiens OX=9606 GN=MAP7 PE=1 SV=1 9.6 3109.7 - 1.24E+06 - - - 0.8336 - 2.883 0.423 - 188.4 1 2 0 0.0014 14 0 0 0 1.37E+07 0.00E+00 - - - 6.0695 0.9996 221125_WJC_METTL3_EV_vs_WT_F04.18408.18408.2 1.15E-06 15/24 R.AGHLC[160.03]TVQFLISK.G "sp|Q8IWZ3|ANKH1_HUMAN,tr|E9PDP5|E9PDP5_HUMAN,tr|H3BLS9|H3BLS9_HUMAN,tr|H7C2F5|H7C2F5_HUMAN" 4 1472.781 2.6 51907 18408 2 1472.779002 737.3978 Ankyrin repeat and KH domain-containing protein 1 OS=Homo sapiens OX=9606 GN=ANKHD1 PE=1 SV=1 8.27 3109.8 - 502556 - - - -1.3362 - 2.519 0.305 - 707.2 1 2 0 -0.002 13 0 0 0 3.68E+06 1.41E+06 - - - 3.6642 1 221125_WJC_METTL3_EV_vs_WT_F04.18411.18411.3 6.84E-07 18/68 R.QISRPSAAGINLMIGSTR.Y sp|Q08211|DHX9_HUMAN 1 1871.0047 0.58 51908 18411 3 1871.002521 624.6755 ATP-dependent RNA helicase A OS=Homo sapiens OX=9606 GN=DHX9 PE=1 SV=4 12 3110.2 - 4.22E+06 - - - -1.1726 - 3.243 0.498 - 348.8 1 2 0 -0.0022 18 0 0 0 4.23E+07 7.24E+07 - - - 7.0212 0.9999 221125_WJC_METTL3_EV_vs_WT_F04.18412.18412.3 0.00134 13/48 K.KGLTPSQIGVILR.D "sp|P62277|RS13_HUMAN,tr|J3KMX5|J3KMX5_HUMAN" 2 1380.8453 0.91 51909 18412 3 1380.842533 461.289 40S ribosomal protein S13 OS=Homo sapiens OX=9606 GN=RPS13 PE=1 SV=2 11 3110.3 - 2.54E+06 - - - -1.993 - 2.779 0.407 - 240 1 2 0 -0.0028 13 0 0 0 2.63E+07 2.90E+07 - - - 5.8481 1 221125_WJC_METTL3_EV_vs_WT_F04.18413.18413.3 4.00E-05 18/48 K.K[136.11]GLTPSQIGVILR[166.11].D "sp|P62277|RS13_HUMAN,tr|J3KMX5|J3KMX5_HUMAN" 2 1398.8678 0.91 51910 18413 3 1398.866803 467.2965 40S ribosomal protein S13 OS=Homo sapiens OX=9606 GN=RPS13 PE=1 SV=2 11 3110.3 - 2.82E+06 - - - -0.6806 - 3.172 0.434 - 451.4 1 2 0 -0.001 13 0 0 0 2.63E+07 2.90E+07 - - - 6.5082 1 221125_WJC_METTL3_EV_vs_WT_F04.18420.18420.3 2.29E-05 24/68 K.FQGEDTVVIASKPYAFDR.V sp|P33176|KINH_HUMAN 1 2042.0109 1.01 51917 18420 3 2042.008407 681.6776 Kinesin-1 heavy chain OS=Homo sapiens OX=9606 GN=KIF5B PE=1 SV=1 4.56 3111.1 - 1.30E+06 - - - -1.2238 - 3.631 0.576 - 778.3 1 2 0 -0.0025 18 0 0 0 8.59E+06 8.50E+06 - - - 8.1721 0.9998 221125_WJC_METTL3_EV_vs_WT_F04.18422.18422.3 7.16E-08 16/64 R.VLELEPNNFEATNELR[166.11]K[136.11].L sp|Q9H6T3|RPAP3_HUMAN 1 2033.0548 1.33 51919 18422 3 2033.048492 678.6922 RNA polymerase II-associated protein 3 OS=Homo sapiens OX=9606 GN=RPAP3 PE=1 SV=2 4.49 3111.4 - 1.10E+06 - - - -3.1224 - 3.011 0.422 - 238 1 2 0 -0.0063 17 0 0 0 8.60E+06 6.49E+06 - - - 6.0278 1 221125_WJC_METTL3_EV_vs_WT_F04.18423.18423.2 5.08E-11 20/34 K.NLEAVETLGSTSTIC[160.03]SDK.T "sp|P05023|AT1A1_HUMAN,sp|P13637|AT1A3_HUMAN,sp|Q13733|AT1A4_HUMAN,sp|P50993|AT1A2_HUMAN,tr|A0A669K9X0|A0A669K9X0_HUMAN,tr|A0A0A0MT26|A0A0A0MT26_HUMAN,tr|H0Y7C1|H0Y7C1_HUMAN,tr|A0A2R8YEY8|A0A2R8YEY8_HUMAN,tr|E9PRA5|E9PRA5_HUMAN,tr|B1AKY9|B1AKY9_HUMAN,tr|M0R116|M0R116_HUMAN" 11 1923.9095 0.92 51920 18423 2 1923.905657 962.962 Sodium\potassium-transporting ATPase subunit alpha-1 OS=Homo sapiens OX=9606 GN=ATP1A1 PE=1 SV=1 4.14 3111.5 - 1.01E+06 - - - -2.0167 - 4.265 0.619 - 1364.5 1 2 0 -0.0039 18 0 0 0 1.75E+07 1.90E+07 - - - 7.1777 0.9995 221125_WJC_METTL3_EV_vs_WT_F04.18424.18424.3 0.0156 Nov-44 R.DIKPDNLLLDAK.G "sp|Q9Y2H1|ST38L_HUMAN,tr|F5H277|F5H277_HUMAN,tr|H0YGN4|H0YGN4_HUMAN" 3 1353.7504 4.06 51921 18424 3 1353.747837 452.2574 Serine\threonine-protein kinase 38-like OS=Homo sapiens OX=9606 GN=STK38L PE=1 SV=3 4.43 3111.6 - 964709 - - - -1.8792 - 2.238 0.308 - 194.4 1 2 0 -0.0025 12 0 0 0 1.83E+07 4.51E+06 - - - 4.2061 0.9993 221125_WJC_METTL3_EV_vs_WT_F04.18425.18425.2 0.00484 30-Dec K.ATPYTFPGGTGQIINK.N "sp|Q10472|GALT1_HUMAN,tr|K7EJV8|K7EJV8_HUMAN" 2 1663.857 2.68 51922 18425 2 1663.853663 832.9358 Polypeptide N-acetylgalactosaminyltransferase 1 OS=Homo sapiens OX=9606 GN=GALNT1 PE=1 SV=1 8.63 3111.8 - 860653 - - - -1.9888 - 1.825 0.393 - 264.2 1 2 0 -0.0033 16 0 0 0 1.56E+07 5.82E+06 - - - 3.4217 0.984 221125_WJC_METTL3_EV_vs_WT_F04.18426.18426.3 1.58E-06 Dec-64 R.PAHVVVGDVLQAADVDK[136.11].T "sp|P30043|BLVRB_HUMAN,tr|A0A2R8YEP4|A0A2R8YEP4_HUMAN,tr|A0A2R8Y7Y9|A0A2R8Y7Y9_HUMAN,tr|M0R192|M0R192_HUMAN,tr|M0QZL1|M0QZL1_HUMAN" 5 1739.9297 0.91 51923 18426 3 1739.932222 580.9839 Flavin reductase (NADPH) OS=Homo sapiens OX=9606 GN=BLVRB PE=1 SV=3 4.41 3111.9 - 833236 - - - 1.4213 - 2.425 0.386 - 120.1 1 1 0 0.0025 17 0 0 0 4.56E+06 4.98E+06 - - - 5.0807 0.9683 221125_WJC_METTL3_EV_vs_WT_F04.18437.18437.3 0.0356 Dec-36 A.ISFHLPINSR[166.11].K "sp|P49755|TMEDA_HUMAN,tr|G3V2K7|G3V2K7_HUMAN" 2 1192.6592 1.36 51932 18437 3 1192.658314 398.5603 Transmembrane emp24 domain-containing protein 10 OS=Homo sapiens OX=9606 GN=TMED10 PE=1 SV=2 9.76 3112.9 - 1.83E+06 - - - -0.7529 - 2.068 0.317 - 158 1 1 0 -0.0009 10 0 0 0 3.16E+07 2.33E+07 - - - 4.1959 1 221125_WJC_METTL3_EV_vs_WT_F04.18439.18439.3 7.75E-06 Dec-52 K.VFHGADSDIEWLQK.D sp|Q01780|EXOSX_HUMAN 1 1643.7944 0.72 51934 18439 3 1643.793656 548.9387 Exosome component 10 OS=Homo sapiens OX=9606 GN=EXOSC10 PE=1 SV=2 4.54 3113.1 - 1.58E+06 - - - -0.435 - 2.623 0.492 - 243.7 1 2 0 -0.0007 14 0 0 0 1.71E+07 2.39E+07 - - - 6.5878 0.9615 221125_WJC_METTL3_EV_vs_WT_F04.18441.18441.3 1.9 Dec-64 K.TPPEDC[160.03]EGPFRPAEILK.E sp|P49790|NU153_HUMAN 1 1954.9459 2.08 51936 18441 3 1954.941076 652.6559 Nuclear pore complex protein Nup153 OS=Homo sapiens OX=9606 GN=NUP153 PE=1 SV=2 4.41 3113.4 - 913293 - - - -2.4487 - 1.917 0.121 - 116.3 1 2 0 -0.0048 17 0 0 0 1.36E+07 6.52E+06 - - - 1.5317 0.9998 221125_WJC_METTL3_EV_vs_WT_F04.18443.18443.3 3.54E-06 15/56 K.INLDK[136.11]LNVTDSVINK[136.11].V sp|Q9BRS2|RIOK1_HUMAN 1 1700.9643 1.58 51938 18443 3 1700.961392 567.9954 Serine\threonine-protein kinase RIO1 OS=Homo sapiens OX=9606 GN=RIOK1 PE=1 SV=2 5.96 3113.6 - 730700 - - - -1.739 - 2.607 0.477 - 154.6 1 2 1 -0.003 15 0 0 0 4.37E+06 2.76E+06 - - - 6.3576 0.9987 221125_WJC_METTL3_EV_vs_WT_F04.18444.18444.3 0.000907 Dec-52 K.MEK[136.11]GEIEAELC[160.03]WAK[136.11].K "sp|Q15643|TRIPB_HUMAN,tr|H0YJ97|H0YJ97_HUMAN" 2 1708.8135 0.001 51939 18444 3 1708.809318 570.6118 Thyroid receptor-interacting protein 11 OS=Homo sapiens OX=9606 GN=TRIP11 PE=1 SV=3 4.49 3113.7 - 728736 - - - -2.4643 - 2.236 0.394 - 188.8 1 2 1 -0.0042 14 0 0 0 0.00E+00 3.97E+06 - - - 5.07 0.9999 221125_WJC_METTL3_EV_vs_WT_F04.18446.18446.3 0.0106 Nov-68 K.NLEAVETLGSTSTIC[160.03]SDK.T "sp|P05023|AT1A1_HUMAN,sp|P13637|AT1A3_HUMAN,sp|Q13733|AT1A4_HUMAN,sp|P50993|AT1A2_HUMAN,tr|A0A669K9X0|A0A669K9X0_HUMAN,tr|A0A0A0MT26|A0A0A0MT26_HUMAN,tr|H0Y7C1|H0Y7C1_HUMAN,tr|A0A2R8YEY8|A0A2R8YEY8_HUMAN,tr|E9PRA5|E9PRA5_HUMAN,tr|B1AKY9|B1AKY9_HUMAN,tr|M0R116|M0R116_HUMAN" 11 1923.9095 13.14 51941 18446 3 1923.912159 642.3105 Sodium\potassium-transporting ATPase subunit alpha-1 OS=Homo sapiens OX=9606 GN=ATP1A1 PE=1 SV=1 4.14 3114 - 639096 - - - 1.3628 - 2.244 0.442 - 149.9 1 2 0 0.0026 18 0 0 0 3.82E+08 2.91E+07 - - - 5.4798 0.9998 221125_WJC_METTL3_EV_vs_WT_F04.18447.18447.2 2.45E-07 28-Dec R.NGYELSPTAAANFTR[166.11].R sp|P49721|PSB2_HUMAN 1 1620.7772 0.55 51942 18447 2 1620.773927 811.3959 Proteasome subunit beta type-2 OS=Homo sapiens OX=9606 GN=PSMB2 PE=1 SV=1 6 3114.1 - 546768 - - - -1.9916 - 2.424 0.565 - 360.1 1 2 0 -0.0032 15 0 0 0 1.96E+06 3.57E+06 - - - 5.3899 0.9991 221125_WJC_METTL3_EV_vs_WT_F04.18449.18449.3 0.00112 Nov-52 K.IKDLSTVEALQNLK.N "sp|Q9BTT0|AN32E_HUMAN,tr|E9PPH5|E9PPH5_HUMAN" 2 1570.893 0.64 51944 18449 3 1570.891147 524.6383 Acidic leucine-rich nuclear phosphoprotein 32 family member E OS=Homo sapiens OX=9606 GN=ANP32E PE=1 SV=1 6.07 3114.4 - 482750 - - - -1.1942 - 2.276 0.351 - 118.2 1 2 1 -0.0019 14 0 0 0 2.56E+06 3.99E+06 - - - 4.6384 0.9977 221125_WJC_METTL3_EV_vs_WT_F04.18450.18450.3 0.0134 Oct-36 R.DYAFVHFTSR.E "sp|A0AV96|RBM47_HUMAN,tr|B7Z8Z7|B7Z8Z7_HUMAN,tr|D6R9D6|D6R9D6_HUMAN" 3 1241.5829 0.64 51945 18450 3 1241.579528 414.8683 RNA-binding protein 47 OS=Homo sapiens OX=9606 GN=RBM47 PE=1 SV=2 6.74 3114.5 - 342280 - - - -2.7336 - 1.665 0.314 - 159.3 1 2 0 -0.0034 10 0 0 0 2.20E+06 3.45E+06 - - - 3.5288 0.9998 221125_WJC_METTL3_EV_vs_WT_F04.18452.18452.2 0.000465 13/24 R.QVQSLTC[160.03]EVDALK.G "sp|P08670|VIME_HUMAN,tr|B0YJC5|B0YJC5_HUMAN,tr|B0YJC4|B0YJC4_HUMAN" 3 1489.7446 2.12 51946 18452 2 1489.744871 745.8796 Vimentin OS=Homo sapiens OX=9606 GN=VIM PE=1 SV=4 4.37 3114.7 - 615300 - - - 0.1524 - 2.454 0.418 - 305.6 1 2 0 0.0002 13 0 0 0 2.18E+08 1.03E+08 - - - 4.4323 0.9947 221125_WJC_METTL3_EV_vs_WT_F04.18455.18455.3 0.000594 Dec-36 A.ISFHLPINSR.K "sp|P49755|TMEDA_HUMAN,tr|G3V2K7|G3V2K7_HUMAN" 2 1182.6509 1.36 51949 18455 3 1182.651031 395.2243 Transmembrane emp24 domain-containing protein 10 OS=Homo sapiens OX=9606 GN=TMED10 PE=1 SV=2 9.76 3114.9 - 3.69E+06 - - - 0.0753 - 2.169 0.456 - 168.4 1 1 0 0.0001 10 0 0 0 3.16E+07 2.33E+07 - - - 5.8851 0.9998 221125_WJC_METTL3_EV_vs_WT_F04.18458.18458.3 5.17E-05 13/60 R.TEPTAQQNLALQLAEK[136.11].L "sp|Q99613|EIF3C_HUMAN,sp|B5ME19|EIFCL_HUMAN" 2 1761.9352 1.55 51952 18458 3 1761.932668 588.319 Eukaryotic translation initiation factor 3 subunit C OS=Homo sapiens OX=9606 GN=EIF3C PE=1 SV=1 4.53 3115.2 - 1.25E+06 - - - -1.4529 - 2.672 0.318 - 219.4 1 2 0 -0.0026 16 0 0 0 2.56E+07 1.65E+07 - - - 4.6065 0.9984 221125_WJC_METTL3_EV_vs_WT_F04.18460.18460.3 1.30E-07 17/52 Y.MSSPC[160.03]HIEMILTEK.E "sp|P18621|RL17_HUMAN,tr|J3QLC8|J3QLC8_HUMAN,tr|J3QQT2|J3QQT2_HUMAN,tr|A0A0A0MRF8|A0A0A0MRF8_HUMAN,tr|J3KRX5|J3KRX5_HUMAN,tr|A0A087WXM6|A0A087WXM6_HUMAN,tr|A0A0A6YYL6|A0A0A6YYL6_HUMAN" 7 1674.7779 0.58 51954 18460 3 1674.776398 559.2666 60S ribosomal protein L17 OS=Homo sapiens OX=9606 GN=RPL17 PE=1 SV=3 5.38 3115.4 - 897357 - - - -0.9177 - 2.985 0.54 - 463.6 1 1 0 -0.0015 14 0 0 0 6.29E+06 1.08E+07 - - - 7.4663 0.9998 221125_WJC_METTL3_EV_vs_WT_F04.18462.18462.3 0.00757 Oct-68 K.FQGEDTVVIASK[136.11]PYAFDR[166.11].V sp|P33176|KINH_HUMAN 1 2060.0334 0.9 51956 18462 3 2060.035964 687.6851 Kinesin-1 heavy chain OS=Homo sapiens OX=9606 GN=KIF5B PE=1 SV=1 4.56 3115.7 - 740851 - - - 1.2563 - 2.162 0.386 - 122.9 1 2 0 0.0026 18 0 0 0 8.78E+06 9.76E+06 - - - 4.7628 0.9999 221125_WJC_METTL3_EV_vs_WT_F04.18463.18463.3 0.0199 Dec-44 R.DIK[136.11]PDNLLLDAK[136.11].G "sp|Q9Y2H1|ST38L_HUMAN,tr|F5H277|F5H277_HUMAN,tr|H0YGN4|H0YGN4_HUMAN" 3 1369.7788 4.22 51957 18463 3 1369.778999 457.6002 Serine\threonine-protein kinase 38-like OS=Homo sapiens OX=9606 GN=STK38L PE=1 SV=3 4.43 3115.8 - 633291 - - - 0.1591 - 2.322 0.381 - 234.5 1 2 0 0.0002 12 0 0 0 1.79E+07 4.26E+06 - - - 5.1228 0.9998 221125_WJC_METTL3_EV_vs_WT_F04.18464.18464.2 5.89E-05 22-Oct R.QSPTLNLLPSSR[166.11].T sp|Q6ZU65|UBN2_HUMAN 1 1321.7229 1.75 51958 18464 2 1321.722884 661.8687 Ubinuclein-2 OS=Homo sapiens OX=9606 GN=UBN2 PE=1 SV=2 9.75 3115.9 - 570276 - - - -0.0378 - 1.941 0.456 - 353.8 1 2 0 -0.0001 12 0 0 0 8.57E+06 4.90E+06 - - - 4.154 0.9994 221125_WJC_METTL3_EV_vs_WT_F04.18468.18468.2 0.0777 22-Jul R.RWEVADLQPQLK.L "sp|P22695|QCR2_HUMAN,tr|H3BP04|H3BP04_HUMAN,tr|H3BRG4|H3BRG4_HUMAN,tr|H3BSJ9|H3BSJ9_HUMAN" 4 1481.7991 5.37 51962 18468 2 1481.797307 741.9068 "Cytochrome b-c1 complex subunit 2, mitochondrial OS=Homo sapiens OX=9606 GN=UQCRC2 PE=1 SV=3" 6.07 3116.4 - 327469 - - - -1.185 - 1.724 0.349 - 184.2 1 2 0 -0.0018 12 0 0 0 6.41E+06 1.19E+06 - - - 3.0512 1 221125_WJC_METTL3_EV_vs_WT_F04.18474.18474.2 1.92E-08 14/34 K.GSPGVPSFAAGPPISEGK.Y "sp|Q15517|CDSN_HUMAN,tr|G8JLG2|G8JLG2_HUMAN,tr|Q2L6G8|Q2L6G8_HUMAN" 3 1653.8362 6.32 51967 18474 2 1653.836598 827.9254 Corneodesmosin OS=Homo sapiens OX=9606 GN=CDSN PE=1 SV=3 6 3117.1 - 1.54E+06 - - - 0.2189 - 2.792 0.612 - 481.5 1 2 0 0.0004 18 0 0 0 1.11E+08 1.76E+07 - - - 6.0855 1 221125_WJC_METTL3_EV_vs_WT_F04.18475.18475.3 1.95E-08 14/56 K.EGYDFHSSSEFEIVK.A "sp|P61163|ACTZ_HUMAN,tr|R4GMT0|R4GMT0_HUMAN,tr|A0A1B0GVS3|A0A1B0GVS3_HUMAN" 3 1772.7893 1.77 51968 18475 3 1772.791262 591.9371 Alpha-centractin OS=Homo sapiens OX=9606 GN=ACTR1A PE=1 SV=1 4.4 3117.2 - 2.68E+06 - - - 1.0808 - 2.438 0.627 - 127.8 1 2 0 0.0019 15 0 0 0 1.85E+07 1.04E+07 - - - 7.8553 1 221125_WJC_METTL3_EV_vs_WT_F04.18476.18476.3 9.05E-07 Dec-52 K.TASNVEEAFINTAK.E "sp|P61019|RAB2A_HUMAN,tr|H7C125|H7C125_HUMAN" 2 1493.7362 0.75 51969 18476 3 1493.738081 498.9193 Ras-related protein Rab-2A OS=Homo sapiens OX=9606 GN=RAB2A PE=1 SV=1 4.53 3117.2 - 2.39E+06 - - - 1.2673 - 2.38 0.558 - 177.3 1 2 0 0.0019 14 0 0 0 1.05E+07 1.39E+07 - - - 7.065 1 221125_WJC_METTL3_EV_vs_WT_F04.18477.18477.3 3.65E-08 15/56 R.NFILDQTNVSAAAQR.R "sp|Q00839|HNRPU_HUMAN,tr|A0A1W2PQL0|A0A1W2PQL0_HUMAN,tr|A0A1W2PPL4|A0A1W2PPL4_HUMAN,tr|A0A1W2PQ74|A0A1W2PQ74_HUMAN,tr|Q5RI18|Q5RI18_HUMAN,tr|A0A1W2PP35|A0A1W2PP35_HUMAN,tr|A0A1W2PPS1|A0A1W2PPS1_HUMAN,tr|A0A1W2PRZ7|A0A1W2PRZ7_HUMAN,tr|A0A1W2PPH7|A0A1W2PPH7_HUMAN,tr|A0A1W2PQD4|A0A1W2PQD4_HUMAN,tr|A0A1W2PP34|A0A1W2PP34_HUMAN,tr|A0A1X7SBS1|A0A1X7SBS1_HUMAN" 12 1646.8376 1.06 51970 18477 3 1646.840607 549.9532 Heterogeneous nuclear ribonucleoprotein U OS=Homo sapiens OX=9606 GN=HNRNPU PE=1 SV=6 5.84 3117.3 - 2.00E+06 - - - 1.8059 - 3.025 0.577 - 314.6 1 2 0 0.003 15 0 0 0 1.13E+09 1.06E+09 - - - 7.8605 1 221125_WJC_METTL3_EV_vs_WT_F04.18478.18478.2 5.22E-06 17/28 R.NFILDQTNVSAAAQR.R "sp|Q00839|HNRPU_HUMAN,tr|A0A1W2PQL0|A0A1W2PQL0_HUMAN,tr|A0A1W2PPL4|A0A1W2PPL4_HUMAN,tr|A0A1W2PQ74|A0A1W2PQ74_HUMAN,tr|Q5RI18|Q5RI18_HUMAN,tr|A0A1W2PP35|A0A1W2PP35_HUMAN,tr|A0A1W2PPS1|A0A1W2PPS1_HUMAN,tr|A0A1W2PRZ7|A0A1W2PRZ7_HUMAN,tr|A0A1W2PPH7|A0A1W2PPH7_HUMAN,tr|A0A1W2PQD4|A0A1W2PQD4_HUMAN,tr|A0A1W2PP34|A0A1W2PP34_HUMAN,tr|A0A1X7SBS1|A0A1X7SBS1_HUMAN" 12 1646.8376 1.03 51971 18478 2 1646.838316 824.4261 Heterogeneous nuclear ribonucleoprotein U OS=Homo sapiens OX=9606 GN=HNRNPU PE=1 SV=6 5.84 3117.4 - 1.97E+06 - - - 0.4147 - 3.325 0.595 - 1093.3 1 2 0 0.0007 15 0 0 0 1.98E+09 1.92E+09 - - - 6.3893 0.9999 221125_WJC_METTL3_EV_vs_WT_F04.18479.18479.3 4.33E-08 17/64 R.NLSDVATKQEGLESVLK.L sp|P14923|PLAK_HUMAN 1 1829.9735 153.55 51972 18479 3 1829.976162 610.9984 Junction plakoglobin OS=Homo sapiens OX=9606 GN=JUP PE=1 SV=3 4.68 3117.4 - 1.24E+06 - - - 1.4776 - 3.004 0.571 - 239.1 1 2 1 0.0027 17 0 0 0 2.11E+07 1.38E+05 - - - 7.6841 0.9998 221125_WJC_METTL3_EV_vs_WT_F04.18483.18483.3 2.85E-08 15/64 R.YRSDGALLLGASSLSGR.C sp|Q9BQA1|MEP50_HUMAN 1 1721.906 1.8 51976 18483 3 1721.908944 574.976 Methylosome protein 50 OS=Homo sapiens OX=9606 GN=WDR77 PE=1 SV=1 8.75 3117.9 - 778654 - - - 1.6824 - 3.305 0.441 - 259.4 1 2 1 0.0029 17 0 0 0 1.41E+08 7.82E+07 - - - 6.4759 0.9993 221125_WJC_METTL3_EV_vs_WT_F04.18486.18486.2 0.0116 22-Oct R.DIKPDNLLLDAK.G "sp|Q9Y2H1|ST38L_HUMAN,tr|F5H277|F5H277_HUMAN,tr|H0YGN4|H0YGN4_HUMAN" 3 1353.7504 3.46 51979 18486 2 1353.751279 677.8825 Serine\threonine-protein kinase 38-like OS=Homo sapiens OX=9606 GN=STK38L PE=1 SV=3 4.43 3118.2 - 632085 - - - 0.6633 - 1.654 0.342 - 167.5 1 2 0 0.0009 12 0 0 0 4.09E+06 1.18E+06 - - - 2.8907 1 221125_WJC_METTL3_EV_vs_WT_F04.18494.18494.2 4.59E-09 13/28 K.QDMPNAMPVSELTDK.L "sp|P84085|ARF5_HUMAN,tr|C9J1Z8|C9J1Z8_HUMAN" 2 1674.7593 1.25 51986 18494 2 1674.763277 838.3869 ADP-ribosylation factor 5 OS=Homo sapiens OX=9606 GN=ARF5 PE=1 SV=2 4.03 3119.2 - 682610 - - - 2.3699 - 2.58 0.643 - 437.1 1 2 0 0.004 15 0 0 0 2.12E+07 1.70E+07 - - - 6.1191 1 221125_WJC_METTL3_EV_vs_WT_F04.18496.18496.2 1.40E-10 17/26 R.VPTANVSVVDLTC[160.03]R.L "sp|P04406|G3P_HUMAN,tr|E7EUT5|E7EUT5_HUMAN" 2 1529.7872 1.09 51988 18496 2 1529.78786 765.9009 Glyceraldehyde-3-phosphate dehydrogenase OS=Homo sapiens OX=9606 GN=GAPDH PE=1 SV=3 5.8 3119.4 - 9.78E+06 - - - 0.4458 - 3.373 0.656 - 1057.2 1 2 0 0.0007 14 0 0 0 6.47E+07 5.92E+07 - - - 6.937 1 221125_WJC_METTL3_EV_vs_WT_F04.18497.18497.2 0.000214 14/24 R.IESLSSQLSNLQK[136.11].E "sp|P20700|LMNB1_HUMAN,tr|E9PBF6|E9PBF6_HUMAN,tr|A0A0D9SFE5|A0A0D9SFE5_HUMAN" 3 1453.7868 1.16 51989 18497 2 1453.787218 727.9007 Lamin-B1 OS=Homo sapiens OX=9606 GN=LMNB1 PE=1 SV=2 6 3119.5 - 2.78E+06 - - - 0.3061 - 2.899 0.555 - 748.3 1 2 0 0.0004 13 0 0 0 7.98E+07 6.88E+07 - - - 5.8718 1 221125_WJC_METTL3_EV_vs_WT_F04.18498.18498.3 1.85E-07 15/52 R.VPTANVSVVDLTC[160.03]R.L "sp|P04406|G3P_HUMAN,tr|E7EUT5|E7EUT5_HUMAN" 2 1529.7872 0.86 51990 18498 3 1529.786547 510.9363 Glyceraldehyde-3-phosphate dehydrogenase OS=Homo sapiens OX=9606 GN=GAPDH PE=1 SV=3 5.8 3119.5 - 2.64E+06 - - - -0.4125 - 2.714 0.546 - 383.3 1 2 0 -0.0006 14 0 0 0 1.52E+07 1.76E+07 - - - 7.2805 0.9999 221125_WJC_METTL3_EV_vs_WT_F04.18499.18499.2 9.48E-05 13/24 R.IESLSSQLSNLQK.E "sp|P20700|LMNB1_HUMAN,tr|E9PBF6|E9PBF6_HUMAN,tr|A0A0D9SFE5|A0A0D9SFE5_HUMAN" 3 1445.7726 1.16 51991 18499 2 1445.772714 723.8936 Lamin-B1 OS=Homo sapiens OX=9606 GN=LMNB1 PE=1 SV=2 6 3119.6 - 2.52E+06 - - - 0.0975 - 2.779 0.509 - 666.6 1 2 0 0.0001 13 0 0 0 7.98E+07 6.88E+07 - - - 5.4237 0.9999 221125_WJC_METTL3_EV_vs_WT_F04.18504.18504.2 5.66E-08 24-Nov K.TAFQEALDAAGDK[136.11].L sp|P10599|THIO_HUMAN 1 1343.6449 0.92 51996 18504 2 1343.644313 672.8297 Thioredoxin OS=Homo sapiens OX=9606 GN=TXN PE=1 SV=3 4.03 3120.1 - 951481 - - - -0.4071 - 2.22 0.606 - 270.4 1 2 0 -0.0005 13 0 0 0 3.59E+06 3.91E+06 - - - 5.5636 1 221125_WJC_METTL3_EV_vs_WT_F04.18506.18506.2 2.36E-07 15/24 K.TAFQEALDAAGDK.L sp|P10599|THIO_HUMAN 1 1335.6307 0.92 51998 18506 2 1335.633767 668.8226 Thioredoxin OS=Homo sapiens OX=9606 GN=TXN PE=1 SV=3 4.03 3120.3 - 902344 - - - 2.3262 - 2.867 0.646 - 534.8 1 2 0 0.0031 13 0 0 0 3.59E+06 3.91E+06 - - - 6.5146 0.997 221125_WJC_METTL3_EV_vs_WT_F04.18508.18508.3 0.191 Jun-56 R.EPFFHGQDNYDQLVR.L "sp|P19784|CSK22_HUMAN,tr|H3BNI9|H3BNI9_HUMAN,tr|H3BSA1|H3BSA1_HUMAN" 3 1863.854 2.94 52000 18508 3 1863.855648 622.2919 Casein kinase II subunit alpha' OS=Homo sapiens OX=9606 GN=CSNK2A2 PE=1 SV=1 4.54 3120.5 - 869376 - - - 0.8783 - 1.315 0.3 - 47.8 1 2 0 0.0016 15 0 0 0 4.83E+06 1.65E+06 - - - 2.5988 0.9996 221125_WJC_METTL3_EV_vs_WT_F04.18509.18509.3 3.71E-05 13/72 K.NLPPSGAVPVTGIPPHVVK.V "sp|Q13283|G3BP1_HUMAN,tr|A0A7I2V5M7|A0A7I2V5M7_HUMAN,tr|A0A7I2YQM1|A0A7I2YQM1_HUMAN,tr|A0A7P0P2U7|A0A7P0P2U7_HUMAN,tr|A0A7I2YQU8|A0A7I2YQU8_HUMAN,tr|A0A7I2V548|A0A7I2V548_HUMAN,tr|A0A7I2V651|A0A7I2V651_HUMAN,tr|A0A7I2V4D8|A0A7I2V4D8_HUMAN,tr|A0A7I2YQN9|A0A7I2YQN9_HUMAN" 9 1878.0727 1.98 52001 18509 3 1878.072018 627.0315 Ras GTPase-activating protein-binding protein 1 OS=Homo sapiens OX=9606 GN=G3BP1 PE=1 SV=1 8.76 3120.6 - 827125 - - - -0.3727 - 2.01 0.329 - 117 1 2 0 -0.0007 19 0 0 0 4.02E+07 2.03E+07 - - - 3.923 1 221125_WJC_METTL3_EV_vs_WT_F04.18510.18510.3 5.43E-05 19/52 K.DLANLEVPHELPTK.Q "sp|Q8WXI9|P66B_HUMAN,tr|A0A0U1RR34|A0A0U1RR34_HUMAN,tr|A0A0U1RRM1|A0A0U1RRM1_HUMAN,tr|A0A0U1RRK3|A0A0U1RRK3_HUMAN" 4 1574.8304 2.12 52002 18510 3 1574.832068 525.9508 Transcriptional repressor p66-beta OS=Homo sapiens OX=9606 GN=GATAD2B PE=1 SV=1 4.65 3120.7 - 808450 - - - 1.0452 - 2.862 0.464 - 286.3 1 2 0 0.0016 14 0 0 0 2.72E+08 1.28E+08 - - - 6.5071 0.9774 221125_WJC_METTL3_EV_vs_WT_F04.18513.18513.3 0.019 Nov-44 K.IEISELNRVIQR.L "sp|P04264|K2C1_HUMAN,sp|P35908|K22E_HUMAN" 2 1468.8362 999 52005 18513 3 1468.836407 490.6193 "Keratin, type II cytoskeletal 1 OS=Homo sapiens OX=9606 GN=KRT1 PE=1 SV=6" 6.14 3121.1 - 641495 - - - 0.1566 - 1.86 0.177 - 147.3 1 2 1 0.0002 12 0 0 0 2.73E+07 0.00E+00 - - - 2.2335 0.994 221125_WJC_METTL3_EV_vs_WT_F04.18519.18519.3 0.000569 14/56 K.QIVSEDKELFNLESR.V sp|Q9NYP9|MS18A_HUMAN 1 1805.9159 0.94 52010 18519 3 1805.924597 602.9793 Protein Mis18-alpha OS=Homo sapiens OX=9606 GN=MIS18A PE=1 SV=1 4.41 3121.7 - 1.42E+06 - - - 4.792 - 2.524 0.387 - 81.1 1 2 1 0.0087 15 0 0 0 6.56E+06 6.95E+06 - - - 5.2681 1 221125_WJC_METTL3_EV_vs_WT_F04.18520.18520.2 3.42E-09 19/30 R.EAATSTLGGLGFSSER.N "sp|Q6W2J9|BCOR_HUMAN,tr|H7BZ37|H7BZ37_HUMAN,tr|H7C2V9|H7C2V9_HUMAN,tr|A0A5F9ZGX7|A0A5F9ZGX7_HUMAN,tr|H7BYY2|H7BYY2_HUMAN,tr|H7C231|H7C231_HUMAN" 6 1581.7635 1.47 52011 18520 2 1581.761359 791.889 BCL-6 corepressor OS=Homo sapiens OX=9606 GN=BCOR PE=1 SV=1 4.53 3121.8 - 1.32E+06 - - - -1.3314 - 3.688 0.62 - 946.7 1 2 0 -0.0021 16 0 0 0 5.42E+07 3.69E+07 - - - 6.8283 1 221125_WJC_METTL3_EV_vs_WT_F04.18521.18521.3 9.20E-06 18/60 R.R[166.11]APEEELPPLDPEEIR[166.11].K "sp|Q8IY67|RAVR1_HUMAN,tr|K7EKR9|K7EKR9_HUMAN,tr|E9PAU2|E9PAU2_HUMAN,tr|A0A087WZ13|A0A087WZ13_HUMAN" 4 1908.9696 1.03 52012 18521 3 1908.968594 637.3305 Ribonucleoprotein PTB-binding 1 OS=Homo sapiens OX=9606 GN=RAVER1 PE=1 SV=1 4.14 3121.9 - 1.01E+06 - - - -0.5254 - 3.082 0.497 - 450.7 1 2 0 -0.001 16 0 0 0 1.60E+08 1.56E+08 - - - 6.9689 0.9999 221125_WJC_METTL3_EV_vs_WT_F04.18525.18525.3 9.69E-07 16/40 R.MNDIVK[136.11]EFEDR[166.11].G sp|P54136|SYRC_HUMAN 1 1412.6725 0.87 52016 18525 3 1412.672135 471.8981 "Arginine--tRNA ligase, cytoplasmic OS=Homo sapiens OX=9606 GN=RARS1 PE=1 SV=2" 4.32 3122.4 - 712962 - - - -0.2478 - 2.965 0.527 - 520.4 1 2 1 -0.0003 11 0 0 0 8.76E+06 1.01E+07 - - - 7.5031 0.9998 221125_WJC_METTL3_EV_vs_WT_F04.18526.18526.3 3.53E-05 14/40 R.MNDIVKEFEDR.G sp|P54136|SYRC_HUMAN 1 1394.65 0.87 52017 18526 3 1394.648768 465.8906 "Arginine--tRNA ligase, cytoplasmic OS=Homo sapiens OX=9606 GN=RARS1 PE=1 SV=2" 4.32 3122.5 - 635875 - - - -0.8941 - 2.445 0.439 - 421.2 1 2 1 -0.0012 11 0 0 0 8.76E+06 1.01E+07 - - - 5.9739 0.9987 221125_WJC_METTL3_EV_vs_WT_F04.18529.18529.2 1.83E-07 Nov-32 R.YRSDGALLLGASSLSGR.C sp|Q9BQA1|MEP50_HUMAN 1 1721.906 3.95 52020 18529 2 1721.904083 861.9603 Methylosome protein 50 OS=Homo sapiens OX=9606 GN=WDR77 PE=1 SV=1 8.75 3122.9 - 385865 - - - -1.1406 - 2.611 0.539 - 59 1 2 1 -0.002 17 0 0 0 6.83E+06 1.73E+06 - - - 5.381 0.9992 221125_WJC_METTL3_EV_vs_WT_F04.18530.18530.2 9.81E-08 Nov-36 K.NGSVVAMTGDGVNDAVALK.A "sp|P98194|AT2C1_HUMAN,tr|H0Y9V7|H0Y9V7_HUMAN,tr|B4E2Q0|B4E2Q0_HUMAN,tr|H0Y9S7|H0Y9S7_HUMAN" 4 1816.8989 -1 52021 18530 2 1816.892253 909.4567 Calcium-transporting ATPase type 2C member 1 OS=Homo sapiens OX=9606 GN=ATP2C1 PE=1 SV=3 4.21 3123.1 - 283993 - - - -3.6656 - 2.158 0.551 - 93.3 1 2 0 -0.0067 19 0 0 0 0.00E+00 0.00E+00 - - - 4.9997 1 221125_WJC_METTL3_EV_vs_WT_F04.18536.18536.3 2.28E-07 19/60 R.RAPEEELPPLDPEEIR.K "sp|Q8IY67|RAVR1_HUMAN,tr|K7EKR9|K7EKR9_HUMAN,tr|E9PAU2|E9PAU2_HUMAN,tr|A0A087WZ13|A0A087WZ13_HUMAN" 4 1888.9531 1.03 52025 18536 3 1888.952762 630.6583 Ribonucleoprotein PTB-binding 1 OS=Homo sapiens OX=9606 GN=RAVER1 PE=1 SV=1 4.14 3123.7 - 1.98E+06 - - - -0.1562 - 2.896 0.575 - 478.5 1 2 0 -0.0003 16 0 0 0 1.60E+08 1.56E+08 - - - 7.679 0.9999 221125_WJC_METTL3_EV_vs_WT_F04.18538.18538.3 2.31E-06 16/68 R.GLRPLELPAVPATEPGNK.K sp|Q9BUA3|SPNDC_HUMAN 1 1858.0312 2 52027 18538 3 1858.030139 620.351 Spindlin interactor and repressor of chromatin-binding protein OS=Homo sapiens OX=9606 GN=SPINDOC PE=1 SV=3 6.14 3123.9 - 799872 - - - -0.5969 - 2.762 0.386 - 303.8 1 2 0 -0.0011 18 0 0 0 9.52E+07 4.75E+07 - - - 5.373 0.9997 221125_WJC_METTL3_EV_vs_WT_F04.18539.18539.3 5.94E-05 15/44 K.NSIEDIHAFAIR.S "sp|Q9NRY5|F1142_HUMAN,tr|E7ESJ7|E7ESJ7_HUMAN" 2 1384.7099 1.32 52028 18539 3 1384.703477 462.5772 Protein FAM114A2 OS=Homo sapiens OX=9606 GN=FAM114A2 PE=1 SV=4 5.32 3124.1 - 514331 - - - -4.6479 - 2.788 0.472 - 395.9 1 2 0 -0.0064 12 0 0 0 7.67E+06 5.81E+06 - - - 6.6426 0.9998 221125_WJC_METTL3_EV_vs_WT_F04.18542.18542.2 0.00301 16-Sep K.DAEAWFNEK.S "sp|P13645|K1C10_HUMAN,sp|Q7Z3Z0|K1C25_HUMAN,sp|Q7Z3Y8|K1C27_HUMAN,sp|Q7Z3Y7|K1C28_HUMAN,tr|A0A1B0GVI3|A0A1B0GVI3_HUMAN" 5 1108.4825 1134.56 52029 18542 2 1108.481041 555.2485 "Keratin, type I cytoskeletal 10 OS=Homo sapiens OX=9606 GN=KRT10 PE=1 SV=6" 4.14 3124.4 - 2.68E+07 - - - -1.3514 - 1.987 0.443 - 354.4 1 2 0 -0.0015 9 0 0 0 1.51E+08 1.33E+05 - - - 4.299 0.9999 221125_WJC_METTL3_EV_vs_WT_F04.18543.18543.3 0.000101 15/64 R.YR[166.11]SDGALLLGASSLSGR[166.11].C sp|Q9BQA1|MEP50_HUMAN 1 1741.9226 1.79 52030 18543 3 1741.920771 581.6481 Methylosome protein 50 OS=Homo sapiens OX=9606 GN=WDR77 PE=1 SV=1 8.75 3124.5 - 5.47E+06 - - - -1.0425 - 2.81 0.483 - 309.3 1 2 1 -0.0018 17 0 0 0 1.41E+08 7.86E+07 - - - 6.5346 0.9995 221125_WJC_METTL3_EV_vs_WT_F04.18546.18546.4 0.00175 18/84 R.VREEVPLELVEAHVK.K sp|Q92922|SMRC1_HUMAN 1 1745.9676 2.59 52033 18546 4 1745.966096 437.4992 SWI\SNF complex subunit SMARCC1 OS=Homo sapiens OX=9606 GN=SMARCC1 PE=1 SV=3 4.91 3124.8 - 1.64E+06 - - - -0.8528 - 2.737 0.401 - 200.1 1 2 1 -0.0015 15 0 0 0 3.22E+07 1.24E+07 - - - 3.0762 1 221125_WJC_METTL3_EV_vs_WT_F04.18548.18548.3 1.03E-09 22/60 K.VADPTPFHIQAEVTMK[136.11].T "sp|P16152|CBR1_HUMAN,tr|E9PQ63|E9PQ63_HUMAN,tr|A8MTM1|A8MTM1_HUMAN" 3 1790.9117 1.46 52035 18548 3 1790.910482 597.9778 Carbonyl reductase [NADPH] 1 OS=Homo sapiens OX=9606 GN=CBR1 PE=1 SV=3 5.32 3125 - 1.49E+06 - - - -0.6555 - 3.963 0.568 - 765.1 1 2 0 -0.0012 16 0 0 0 4.26E+07 2.93E+07 - - - 8.4055 0.8928 221125_WJC_METTL3_EV_vs_WT_F04.18549.18549.3 1.52 Aug-48 R.IESLSSQLSNLQK[136.11].E "sp|P20700|LMNB1_HUMAN,tr|E9PBF6|E9PBF6_HUMAN,tr|A0A0D9SFE5|A0A0D9SFE5_HUMAN" 3 1453.7868 1.15 52036 18549 3 1453.788042 485.6029 Lamin-B1 OS=Homo sapiens OX=9606 GN=LMNB1 PE=1 SV=2 6 3125.1 - 1.21E+06 - - - 0.8729 - 1.508 0.082 - 106.8 2 2 0 0.0013 13 0 0 0 9.97E+06 8.70E+06 - - - 0.4283 0.9999 221125_WJC_METTL3_EV_vs_WT_F04.18550.18550.3 7.65E-05 Sep-44 R.ADLTEYLSTHYK.A sp|P31930|QCR1_HUMAN 1 1439.6933 0.99 52037 18550 3 1439.691842 480.905 "Cytochrome b-c1 complex subunit 1, mitochondrial OS=Homo sapiens OX=9606 GN=UQCRC1 PE=1 SV=3" 5.32 3125.3 - 1.15E+06 - - - -0.9849 - 2.212 0.444 - 142.7 1 2 0 -0.0014 12 0 0 0 2.71E+07 2.74E+07 - - - 5.6903 1 221125_WJC_METTL3_EV_vs_WT_F04.18555.18555.3 5.33E-06 14/56 R.NFILDQTNVSAAAQR[166.11].R "sp|Q00839|HNRPU_HUMAN,tr|A0A1W2PQL0|A0A1W2PQL0_HUMAN,tr|A0A1W2PPL4|A0A1W2PPL4_HUMAN,tr|A0A1W2PQ74|A0A1W2PQ74_HUMAN,tr|Q5RI18|Q5RI18_HUMAN,tr|A0A1W2PP35|A0A1W2PP35_HUMAN,tr|A0A1W2PPS1|A0A1W2PPS1_HUMAN,tr|A0A1W2PRZ7|A0A1W2PRZ7_HUMAN,tr|A0A1W2PPH7|A0A1W2PPH7_HUMAN,tr|A0A1W2PQD4|A0A1W2PQD4_HUMAN,tr|A0A1W2PP34|A0A1W2PP34_HUMAN,tr|A0A1X7SBS1|A0A1X7SBS1_HUMAN" 12 1656.8459 1.06 52041 18555 3 1656.84267 553.2892 Heterogeneous nuclear ribonucleoprotein U OS=Homo sapiens OX=9606 GN=HNRNPU PE=1 SV=6 5.84 3125.9 - 9.81E+07 - - - -1.9513 - 2.618 0.556 - 213.2 1 2 0 -0.0032 15 0 0 0 1.13E+09 1.06E+09 - - - 7.2492 0.9999 221125_WJC_METTL3_EV_vs_WT_F04.18559.18559.3 4.25E-10 19/60 K.VADPTPFHIQAEVTMK.T "sp|P16152|CBR1_HUMAN,tr|E9PQ63|E9PQ63_HUMAN,tr|A8MTM1|A8MTM1_HUMAN" 3 1782.8975 1.46 52044 18559 3 1782.891097 595.3064 Carbonyl reductase [NADPH] 1 OS=Homo sapiens OX=9606 GN=CBR1 PE=1 SV=3 5.32 3126.2 - 2.77E+06 - - - -3.5667 - 3.82 0.58 - 626 1 2 0 -0.0064 16 0 0 0 4.25E+07 2.92E+07 - - - 8.4436 1 221125_WJC_METTL3_EV_vs_WT_F04.18560.18560.2 1.71E-12 17/28 R.NPDDITNEEYGEFYK.S sp|P07900|HS90A_HUMAN 1 1832.7741 0.73 52045 18560 2 1832.772195 917.3943 Heat shock protein HSP 90-alpha OS=Homo sapiens OX=9606 GN=HSP90AA1 PE=1 SV=5 3.83 3126.3 - 2.51E+06 - - - -1.0334 - 3.376 0.761 - 353 1 2 0 -0.0019 15 0 0 0 6.55E+07 9.01E+07 - - - 7.6524 0.9995 221125_WJC_METTL3_EV_vs_WT_F04.18561.18561.2 0.00142 22-Oct K.DSTDISAVLGTK.A "sp|O75410|TACC1_HUMAN,tr|E5RFM9|E5RFM9_HUMAN,tr|R4GMT7|R4GMT7_HUMAN" 3 1205.6139 1.01 52046 18561 2 1205.611465 603.8142 Transforming acidic coiled-coil-containing protein 1 OS=Homo sapiens OX=9606 GN=TACC1 PE=1 SV=2 4.21 3126.3 - 2.02E+06 - - - -2.0587 - 1.959 0.416 - 143 1 2 0 -0.0025 12 0 0 0 5.90E+07 5.82E+07 - - - 3.8821 0.9998 221125_WJC_METTL3_EV_vs_WT_F04.18562.18562.3 0.00122 Nov-44 R.ADLTEYLSTHYK[136.11].A sp|P31930|QCR1_HUMAN 1 1447.7075 0.99 52047 18562 3 1447.705978 483.5764 "Cytochrome b-c1 complex subunit 1, mitochondrial OS=Homo sapiens OX=9606 GN=UQCRC1 PE=1 SV=3" 5.32 3126.4 - 1.93E+06 - - - -1.0237 - 2.267 0.338 - 197.3 1 2 0 -0.0015 12 0 0 0 2.71E+07 2.74E+07 - - - 4.5766 0.9998 221125_WJC_METTL3_EV_vs_WT_F04.18563.18563.2 6.08E-06 22-Oct K.DSTDISAVLGTK[136.11].A "sp|O75410|TACC1_HUMAN,tr|E5RFM9|E5RFM9_HUMAN,tr|R4GMT7|R4GMT7_HUMAN" 3 1213.6281 1.01 52048 18563 2 1213.626136 607.8213 Transforming acidic coiled-coil-containing protein 1 OS=Homo sapiens OX=9606 GN=TACC1 PE=1 SV=2 4.21 3126.5 - 1.89E+06 - - - -1.657 - 2.435 0.512 - 379.9 1 2 0 -0.002 12 0 0 0 5.90E+07 5.82E+07 - - - 5.1636 1 221125_WJC_METTL3_EV_vs_WT_F04.18565.18565.2 4.71E-06 15/28 K.QDMPNAMPVSELTDK[136.11].L "sp|P84085|ARF5_HUMAN,tr|C9J1Z8|C9J1Z8_HUMAN" 2 1682.7735 1.25 52050 18565 2 1682.770574 842.394 ADP-ribosylation factor 5 OS=Homo sapiens OX=9606 GN=ARF5 PE=1 SV=2 4.03 3126.8 - 1.35E+06 - - - -1.7436 - 2.823 0.584 - 561.9 1 2 0 -0.0029 15 0 0 0 2.12E+07 1.70E+07 - - - 5.905 0.9998 221125_WJC_METTL3_EV_vs_WT_F04.18566.18566.4 1.35E-06 17/84 R.VR[166.11]EEVPLELVEAHVK[136.11].K sp|Q92922|SMRC1_HUMAN 1 1763.9901 2.59 52051 18566 4 1763.985656 442.0048 SWI\SNF complex subunit SMARCC1 OS=Homo sapiens OX=9606 GN=SMARCC1 PE=1 SV=3 4.91 3126.9 - 1.19E+06 - - - -2.4938 - 2.764 0.52 - 210.5 1 2 1 -0.0044 15 0 0 0 3.22E+07 1.24E+07 - - - 4.1146 0.9999 221125_WJC_METTL3_EV_vs_WT_F04.18567.18567.2 1.95E-05 22-Nov R.GSTDNLMDDIER[166.11].A sp|P50990|TCPQ_HUMAN 1 1374.5961 0.37 52052 18567 2 1374.594647 688.3053 T-complex protein 1 subunit theta OS=Homo sapiens OX=9606 GN=CCT8 PE=1 SV=4 3.84 3127.1 - 1.07E+06 - - - -1.0418 - 2.473 0.505 - 419.4 1 2 0 -0.0014 12 0 0 0 2.47E+08 6.71E+08 - - - 5.1528 0.9999 221125_WJC_METTL3_EV_vs_WT_F04.18569.18569.3 0.00205 16/40 R.FQELLQDLEK[136.11]K[136.11].E sp|Q8TAE8|G45IP_HUMAN 1 1405.7788 1.59 52054 18569 3 1405.775406 469.6002 Growth arrest and DNA damage-inducible proteins-interacting protein 1 OS=Homo sapiens OX=9606 GN=GADD45GIP1 PE=1 SV=1 4.68 3127.3 - 983227 - - - -2.4008 - 3.158 0.365 - 229.6 1 2 0 -0.0034 11 0 0 0 7.06E+07 4.43E+07 - - - 5.8752 1 221125_WJC_METTL3_EV_vs_WT_F04.18571.18571.2 7.90E-09 Dec-36 R.MGVFAQADGSAYIEQGNTK.A "sp|Q9NPD3|EXOS4_HUMAN,tr|E9PPI9|E9PPI9_HUMAN" 2 1985.9153 1.04 52056 18571 2 1985.911705 993.9649 Exosome complex component RRP41 OS=Homo sapiens OX=9606 GN=EXOSC4 PE=1 SV=3 4.37 3127.6 - 530263 - - - -1.8057 - 2.752 0.678 - 231.7 1 2 0 -0.0036 19 0 0 0 2.79E+06 2.69E+06 - - - 6.5364 1 221125_WJC_METTL3_EV_vs_WT_F04.18575.18575.3 0.00185 16/64 K.FVINYDYPNSSEDYVHR.L "sp|Q92841|DDX17_HUMAN,tr|A0A5H1ZRQ2|A0A5H1ZRQ2_HUMAN,tr|A0A1X7SBZ2|A0A1X7SBZ2_HUMAN" 3 2116.949 1.1 52059 18575 3 2116.947579 706.657 Probable ATP-dependent RNA helicase DDX17 OS=Homo sapiens OX=9606 GN=DDX17 PE=1 SV=2 4.54 3127.9 - 7.06E+06 - - - -0.6873 - 3.05 0.566 - 311.7 1 2 0 -0.0015 17 0 0 0 1.71E+08 1.56E+08 - - - 7.6671 0.9999 221125_WJC_METTL3_EV_vs_WT_F04.18576.18576.3 0.0739 15/40 R.FQELLQDLEKK.E sp|Q8TAE8|G45IP_HUMAN 1 1389.7504 1.6 52060 18576 3 1389.749502 464.2574 Growth arrest and DNA damage-inducible proteins-interacting protein 1 OS=Homo sapiens OX=9606 GN=GADD45GIP1 PE=1 SV=1 4.68 3128 - 2.50E+06 - - - -0.6325 - 2.74 0.4 - 187.9 1 2 0 -0.0009 11 0 0 0 7.08E+07 4.43E+07 - - - 5.8628 1 221125_WJC_METTL3_EV_vs_WT_F04.18578.18578.3 0.0001 Dec-48 K.NGIHDLDNISFPK[136.11].Q "sp|P49721|PSB2_HUMAN,tr|A0A087WVV1|A0A087WVV1_HUMAN" 2 1476.7452 0.88 52062 18578 3 1476.743105 493.2557 Proteasome subunit beta type-2 OS=Homo sapiens OX=9606 GN=PSMB2 PE=1 SV=1 5.21 3128.2 - 1.85E+06 - - - -1.4478 - 2.182 0.507 - 133.2 1 2 0 -0.0021 13 0 0 0 2.06E+07 2.33E+07 - - - 6.3074 0.9999 221125_WJC_METTL3_EV_vs_WT_F04.18579.18579.2 1.75E-05 22-Nov R.GSTDNLMDDIER.A sp|P50990|TCPQ_HUMAN 1 1364.5878 0.37 52063 18579 2 1364.587164 683.3012 T-complex protein 1 subunit theta OS=Homo sapiens OX=9606 GN=CCT8 PE=1 SV=4 3.84 3128.3 - 1.68E+06 - - - -0.4727 - 2.662 0.54 - 449.1 1 2 0 -0.0006 12 0 0 0 2.47E+08 6.71E+08 - - - 5.6054 0.9998 221125_WJC_METTL3_EV_vs_WT_F04.18580.18580.2 0.000215 16/26 K.DLANLEVPHELPTK.Q "sp|Q8WXI9|P66B_HUMAN,tr|A0A0U1RR34|A0A0U1RR34_HUMAN,tr|A0A0U1RRM1|A0A0U1RRM1_HUMAN,tr|A0A0U1RRK3|A0A0U1RRK3_HUMAN" 4 1574.8304 7.69 52064 18580 2 1574.833405 788.4225 Transcriptional repressor p66-beta OS=Homo sapiens OX=9606 GN=GATAD2B PE=1 SV=1 4.65 3128.4 - 1.11E+06 - - - 1.8942 - 3.078 0.515 - 855.1 1 2 0 0.003 14 0 0 0 1.80E+07 2.34E+06 - - - 5.6652 1 221125_WJC_METTL3_EV_vs_WT_F04.18582.18582.3 1.18E-06 16/60 K.QSPLGFEVHDEITVTR.Q sp|O95347|SMC2_HUMAN 1 1826.9163 6.4 52066 18582 3 1826.912715 609.9794 Structural maintenance of chromosomes protein 2 OS=Homo sapiens OX=9606 GN=SMC2 PE=1 SV=2 4.65 3128.6 - 739218 - - - -1.9497 - 3.197 0.573 - 285.6 1 2 0 -0.0036 16 0 0 0 7.55E+06 1.18E+06 - - - 7.9095 1 221125_WJC_METTL3_EV_vs_WT_F04.18586.18586.2 1.66E-05 19/30 R.EAATSTLGGLGFSSER[166.11].N "sp|Q6W2J9|BCOR_HUMAN,tr|H7BZ37|H7BZ37_HUMAN,tr|H7C2V9|H7C2V9_HUMAN,tr|A0A5F9ZGX7|A0A5F9ZGX7_HUMAN,tr|H7BYY2|H7BYY2_HUMAN,tr|H7C231|H7C231_HUMAN" 6 1591.7717 1.47 52068 18586 2 1591.773684 796.8931 BCL-6 corepressor OS=Homo sapiens OX=9606 GN=BCOR PE=1 SV=1 4.53 3129.2 - 1.49E+06 - - - 1.2244 - 3.486 0.59 - 936.7 1 2 0 0.0019 16 0 0 0 5.41E+07 3.69E+07 - - - 6.4682 1 221125_WJC_METTL3_EV_vs_WT_F04.18587.18587.3 6.69E-08 16/72 R.IGDLQAFQGHGAGNLAGLK.G "sp|P08195|4F2_HUMAN,tr|A0A7P0TAN7|A0A7P0TAN7_HUMAN,tr|J3KPF3|J3KPF3_HUMAN,tr|H0YH36|H0YH36_HUMAN,tr|A0A7P0TAT7|A0A7P0TAT7_HUMAN,tr|H0YFS2|H0YFS2_HUMAN,tr|A0A7P0T8U7|A0A7P0T8U7_HUMAN,tr|A0A7P0T8F1|A0A7P0T8F1_HUMAN,tr|A0A7P0Z4A0|A0A7P0Z4A0_HUMAN,tr|F5GZS6|F5GZS6_HUMAN,tr|A0A7P0Z4P5|A0A7P0Z4P5_HUMAN,tr|A0A7P0TAS6|A0A7P0TAS6_HUMAN" 12 1865.9748 1.73 52069 18587 3 1865.974347 622.9989 4F2 cell-surface antigen heavy chain OS=Homo sapiens OX=9606 GN=SLC3A2 PE=1 SV=3 6.74 3129.2 - 1.58E+06 - - - -0.2401 - 3.321 0.552 - 264.4 1 2 0 -0.0004 19 0 0 0 5.20E+07 3.00E+07 - - - 7.6429 0.9997 221125_WJC_METTL3_EV_vs_WT_F04.18588.18588.3 3.78E-06 16/44 R.KLEAELLQIEER.H "sp|Q969G3|SMCE1_HUMAN,tr|A0A2R8Y855|A0A2R8Y855_HUMAN,tr|A0A2R8YES3|A0A2R8YES3_HUMAN,tr|A0A2U3TZQ7|A0A2U3TZQ7_HUMAN,tr|A0A2R8Y7U4|A0A2R8Y7U4_HUMAN,tr|B4DGM3|B4DGM3_HUMAN,tr|J3QKS7|J3QKS7_HUMAN,tr|A0A2R8Y4T4|A0A2R8Y4T4_HUMAN,tr|A0A2R8Y7I9|A0A2R8Y7I9_HUMAN,tr|J3QR61|J3QR61_HUMAN,tr|A0A2R8Y765|A0A2R8Y765_HUMAN" 11 1469.809 1.89 52070 18588 3 1469.808768 490.9436 SWI\SNF-related matrix-associated actin-dependent regulator of chromatin subfamily E member 1 OS=Homo sapiens OX=9606 GN=SMARCE1 PE=1 SV=2 4.49 3129.3 - 1.48E+06 - - - -0.1299 - 2.827 0.243 - 529.4 1 2 0 -0.0002 12 0 0 0 2.59E+07 1.37E+07 - - - 4.1297 0.9999 221125_WJC_METTL3_EV_vs_WT_F04.18597.18597.2 2.42E-06 20-Nov R.SSSGLLEWESK.S "sp|P14866|HNRPL_HUMAN,tr|M0QYT0|M0QYT0_HUMAN,tr|A0A3B3ITJ4|A0A3B3ITJ4_HUMAN,tr|M0QXS5|M0QXS5_HUMAN,tr|M0R076|M0R076_HUMAN" 5 1221.5877 1.62 52077 18597 2 1221.587954 611.8011 Heterogeneous nuclear ribonucleoprotein L OS=Homo sapiens OX=9606 GN=HNRNPL PE=1 SV=2 4.53 3130.3 - 1.24E+06 - - - 0.1809 - 2.394 0.484 - 329.4 1 2 0 0.0002 11 0 0 0 1.74E+07 1.07E+07 - - - 4.9773 0.9998 221125_WJC_METTL3_EV_vs_WT_F04.18601.18601.2 1.06E-07 13/38 K.AIGGEFSDTNAAVEGTPLPK.A "sp|O75410|TACC1_HUMAN,tr|E7EVI4|E7EVI4_HUMAN,tr|E5RJU4|E5RJU4_HUMAN,tr|E5RFM9|E5RFM9_HUMAN,tr|R4GMT7|R4GMT7_HUMAN,tr|H0YAY0|H0YAY0_HUMAN,tr|E7ET87|E7ET87_HUMAN" 7 1972.9742 2.21 52081 18601 2 1972.974735 987.4944 Transforming acidic coiled-coil-containing protein 1 OS=Homo sapiens OX=9606 GN=TACC1 PE=1 SV=2 4.14 3130.9 - 573953 - - - 0.2783 - 2.984 0.313 - 306.9 1 2 0 0.0005 20 0 0 0 1.07E+07 4.87E+06 - - - 4.0405 1 221125_WJC_METTL3_EV_vs_WT_F04.18602.18602.3 1.01E-05 14/48 K.TQIHFDPEVVQIK.A "sp|Q9NS73|MBIP1_HUMAN,tr|S4R2X9|S4R2X9_HUMAN,tr|S4R3P6|S4R3P6_HUMAN,tr|S4R3N2|S4R3N2_HUMAN,tr|S4R3Y0|S4R3Y0_HUMAN,tr|A0A087X1L0|A0A087X1L0_HUMAN" 6 1552.8249 0.69 52082 18602 3 1552.824486 518.6156 MAP3K12-binding inhibitory protein 1 OS=Homo sapiens OX=9606 GN=MBIP PE=1 SV=2 5.29 3131 - 493800 - - - -0.2943 - 2.435 0.476 - 193.7 1 2 0 -0.0005 13 0 0 0 1.89E+07 2.72E+07 - - - 6.2597 1 221125_WJC_METTL3_EV_vs_WT_F04.18607.18607.3 1.31E-05 21/64 K.VTAEVVLAHLGGGSTSR[166.11].A "sp|P04843|RPN1_HUMAN,tr|F8WF32|F8WF32_HUMAN" 2 1662.8929 1.19 52085 18607 3 1662.892246 555.3049 Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit 1 OS=Homo sapiens OX=9606 GN=RPN1 PE=1 SV=1 6.72 3131.6 - 7.04E+06 - - - -0.365 - 3.426 0.536 - 644.2 1 2 0 -0.0006 17 0 0 0 1.38E+08 1.16E+08 - - - 7.6266 0.9999 221125_WJC_METTL3_EV_vs_WT_F04.18609.18609.3 1.16E-05 Dec-44 R.QLFHPEQLITGK[136.11].E "sp|Q9NY65|TBA8_HUMAN,sp|Q6PEY2|TBA3E_HUMAN,sp|P0DPH7|TBA3C_HUMAN,sp|Q71U36|TBA1A_HUMAN,sp|P0DPH8|TBA3D_HUMAN,sp|Q9H853|TBA4B_HUMAN,sp|P68366|TBA4A_HUMAN,sp|P68363|TBA1B_HUMAN,sp|Q9BQE3|TBA1C_HUMAN,tr|C9JJQ8|C9JJQ8_HUMAN,tr|F8VS66|F8VS66_HUMAN,tr|F8VWV9|F8VWV9_HUMAN,tr|F8VRZ4|F8VRZ4_HUMAN,tr|F8VVB9|F8VVB9_HUMAN,tr|C9JQ00|C9JQ00_HUMAN,tr|C9JEV8|C9JEV8_HUMAN,tr|A0A7P0TA31|A0A7P0TA31_HUMAN,tr|A0A1W2PQM2|A0A1W2PQM2_HUMAN,tr|F5H5D3|F5H5D3_HUMAN,tr|C9J2C0|C9J2C0_HUMAN,tr|C9K0S6|C9K0S6_HUMAN,tr|C9JDL2|C9JDL2_HUMAN,tr|F8VQQ4|F8VQQ4_HUMAN,tr|F8VX09|F8VX09_HUMAN,tr|A0A7P0T945|A0A7P0T945_HUMAN" 25 1417.7809 0.56 52087 18609 3 1417.781057 473.6009 Tubulin alpha-8 chain OS=Homo sapiens OX=9606 GN=TUBA8 PE=1 SV=1 6.75 3131.8 - 1.43E+06 - - - 0.1107 - 2.169 0.391 - 239.5 1 2 0 0.0002 12 0 0 0 9.42E+07 1.68E+08 - - - 5.0454 0.9999 221125_WJC_METTL3_EV_vs_WT_F04.18610.18610.2 0.000293 20-Nov R.FQELLQDLEKK.E sp|Q8TAE8|G45IP_HUMAN 1 1389.7504 1.85 52088 18610 2 1389.749286 695.8825 Growth arrest and DNA damage-inducible proteins-interacting protein 1 OS=Homo sapiens OX=9606 GN=GADD45GIP1 PE=1 SV=1 4.68 3131.9 - 607964 - - - -0.7879 - 2.35 0.453 - 383.6 1 2 0 -0.0011 11 0 0 0 6.69E+06 3.61E+06 - - - 4.6979 0.9998 221125_WJC_METTL3_EV_vs_WT_F04.18611.18611.4 4.56E-05 18/108 K.LVEKPSPLTLAPHDFANIK.A sp|P53618|COPB_HUMAN 1 2089.1572 0.54 52089 18611 4 2089.162798 523.2966 Coatomer subunit beta OS=Homo sapiens OX=9606 GN=COPB1 PE=1 SV=3 6.75 3132 - 536471 - - - 2.691 - 3.15 0.44 - 213.1 1 2 0 0.0056 19 0 0 0 7.56E+06 1.39E+07 - - - 3.4423 0.9998 221125_WJC_METTL3_EV_vs_WT_F04.18613.18613.3 0.00105 Aug-44 R.GSTDNLMDDIER[166.11].A sp|P50990|TCPQ_HUMAN 1 1374.5961 0.37 52091 18613 3 1374.595269 459.206 T-complex protein 1 subunit theta OS=Homo sapiens OX=9606 GN=CCT8 PE=1 SV=4 3.84 3132.3 - 429670 - - - -0.5893 - 1.463 0.46 - 86 1 2 0 -0.0008 12 0 0 0 2.67E+06 7.27E+06 - - - 4.723 0.9999 221125_WJC_METTL3_EV_vs_WT_F04.18614.18614.3 0.000152 Oct-64 K.VPDGKPENEFAFNAEFK.D sp|Q15181|IPYR_HUMAN 1 1937.9159 0.31 52092 18614 3 1937.915016 646.9793 Inorganic pyrophosphatase OS=Homo sapiens OX=9606 GN=PPA1 PE=1 SV=2 4.41 3132.4 - 353722 - - - -0.4783 - 2.174 0.404 - 86 1 2 0 -0.0009 17 0 0 0 6.63E+06 2.15E+07 - - - 5.0058 0.9923 221125_WJC_METTL3_EV_vs_WT_F04.18615.18615.3 0.0149 Jul-32 K.NK[136.11]DLVEWLK[136.11].L sp|Q9P2D1|CHD7_HUMAN 1 1159.6572 1.21 52093 18615 3 1159.655133 387.5597 Chromodomain-helicase-DNA-binding protein 7 OS=Homo sapiens OX=9606 GN=CHD7 PE=1 SV=3 6.07 3132.6 - 336167 - - - -1.7902 - 1.634 0.29 - 105.6 1 2 1 -0.0021 9 0 0 0 6.35E+06 5.23E+06 - - - 3.2525 1 221125_WJC_METTL3_EV_vs_WT_F04.18619.18619.3 3.43E-09 20/64 K.VTAEVVLAHLGGGSTSR.A "sp|P04843|RPN1_HUMAN,tr|F8WF32|F8WF32_HUMAN" 2 1652.8846 1.19 52095 18619 3 1652.885282 551.9688 Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit 1 OS=Homo sapiens OX=9606 GN=RPN1 PE=1 SV=1 6.72 3133.1 - 1.01E+07 - - - 0.4229 - 3.663 0.591 - 645.5 1 2 0 0.0007 17 0 0 0 1.38E+08 1.16E+08 - - - 8.4087 0.9908 221125_WJC_METTL3_EV_vs_WT_F04.18620.18620.3 0.00272 13/40 K.EK[136.11]FEEMIQQIK[136.11].E "sp|P48643|TCPE_HUMAN,tr|E9PCA1|E9PCA1_HUMAN,tr|B7ZAR1|B7ZAR1_HUMAN,tr|E7ENZ3|E7ENZ3_HUMAN" 4 1437.7509 0.57 52096 18620 3 1437.750821 480.2576 T-complex protein 1 subunit epsilon OS=Homo sapiens OX=9606 GN=CCT5 PE=1 SV=1 4.79 3133.2 - 2.26E+06 - - - -0.0216 - 2.276 0.175 - 355.6 1 2 1 0 11 0 0 0 7.61E+07 1.34E+08 - - - 2.8274 1 221125_WJC_METTL3_EV_vs_WT_F04.18621.18621.3 1.60E-10 20/68 R.ELGIC[160.03]PDDAAVIPIKNNR.F sp|P12273|PIP_HUMAN 1 1994.0255 118.27 52097 18621 3 1994.028002 665.6824 Prolactin-inducible protein OS=Homo sapiens OX=9606 GN=PIP PE=1 SV=1 4.56 3133.2 - 1.82E+06 - - - 1.2492 - 3.347 0.655 - 402.7 1 2 1 0.0025 18 0 0 0 4.08E+07 3.45E+05 - - - 8.8501 0.9987 221125_WJC_METTL3_EV_vs_WT_F04.18623.18623.3 0.00548 13/52 K.VC[160.03]AHITNIPFSITK.M sp|Q9NTZ6|RBM12_HUMAN 1 1599.8443 0.56 52099 18623 3 1599.842396 534.2887 RNA-binding protein 12 OS=Homo sapiens OX=9606 GN=RBM12 PE=1 SV=1 8.2 3133.5 - 629397 - - - -1.1895 - 1.983 0.252 - 217.8 1 2 0 -0.0019 14 0 0 0 9.64E+06 1.73E+07 - - - 3.1684 0.9994 221125_WJC_METTL3_EV_vs_WT_F04.18625.18625.3 3.60E-05 Dec-40 K.LK[136.11]VPEWVDTVK[136.11].L "sp|P39019|RS19_HUMAN,tr|M0R140|M0R140_HUMAN,tr|M0R2L9|M0R2L9_HUMAN,tr|M0QYF7|M0QYF7_HUMAN" 4 1328.7675 1.11 52101 18625 3 1328.77014 443.9298 40S ribosomal protein S19 OS=Homo sapiens OX=9606 GN=RPS19 PE=1 SV=2 6.07 3133.7 - 539796 - - - 1.9958 - 1.982 0.455 - 203.3 1 2 1 0.0027 11 0 0 0 5.61E+07 5.03E+07 - - - 5.5555 0.9987 221125_WJC_METTL3_EV_vs_WT_F04.18629.18629.2 0.000366 13/20 K.EK[136.11]FEEMIQQIK[136.11].E "sp|P48643|TCPE_HUMAN,tr|E9PCA1|E9PCA1_HUMAN,tr|B7ZAR1|B7ZAR1_HUMAN,tr|E7ENZ3|E7ENZ3_HUMAN" 4 1437.7509 0.63 52103 18629 2 1437.751327 719.8827 T-complex protein 1 subunit epsilon OS=Homo sapiens OX=9606 GN=CCT5 PE=1 SV=1 4.79 3134.2 - 1.17E+06 - - - 0.3304 - 2.398 0.479 - 461 1 2 1 0.0005 11 0 0 0 2.84E+07 4.55E+07 - - - 4.9448 0.8706 221125_WJC_METTL3_EV_vs_WT_F04.18630.18630.3 0.0011 15/52 R.RTDIFGVEETAIGK.K sp|Q15459|SF3A1_HUMAN 1 1534.7991 0.74 52104 18630 3 1535.790505 512.607 Splicing factor 3A subunit 1 OS=Homo sapiens OX=9606 GN=SF3A1 PE=1 SV=1 4.68 3134.4 - 572780 - - - 645.9366 - 2.737 0.442 - 339.1 1 2 0 0.9914 14 0 0 0 1.32E+07 1.79E+07 - - - 5.869 1 221125_WJC_METTL3_EV_vs_WT_F04.18632.18632.2 1.88E-13 17/28 R.NPDDITNEEYGEFYK[136.11].S sp|P07900|HS90A_HUMAN 1 1840.7883 0.72 52106 18632 2 1840.788756 921.4014 Heat shock protein HSP 90-alpha OS=Homo sapiens OX=9606 GN=HSP90AA1 PE=1 SV=5 3.83 3134.5 - 1.43E+06 - - - 0.2537 - 3.525 0.782 - 1184.6 1 2 0 0.0005 15 0 0 0 6.55E+07 9.09E+07 - - - 7.9142 0.9998 221125_WJC_METTL3_EV_vs_WT_F04.18633.18633.3 6.33E-05 13/48 K.TLYNNQPIDFLKK.M "sp|Q13867|BLMH_HUMAN,tr|K7ESE8|K7ESE8_HUMAN,tr|J3KSD8|J3KSD8_HUMAN,tr|K7ES02|K7ES02_HUMAN" 4 1592.8562 7.16 52107 18633 3 1592.860285 531.9594 Bleomycin hydrolase OS=Homo sapiens OX=9606 GN=BLMH PE=1 SV=1 8.17 3134.6 - 864686 - - - 2.5376 - 2.091 0.458 - 118.1 1 2 0 0.004 13 0 0 0 2.38E+07 3.32E+06 - - - 5.6451 1 221125_WJC_METTL3_EV_vs_WT_F04.18634.18634.3 1.12E-08 23/80 M.IPGGLSEAKPATPEIQEIVDK.V "sp|P01040|CYTA_HUMAN,tr|C9J0E4|C9J0E4_HUMAN" 2 2191.1736 999 52108 18634 3 2191.176019 731.3985 Cystatin-A OS=Homo sapiens OX=9606 GN=CSTA PE=1 SV=1 4.41 3134.8 - 792231 - - - 1.0976 - 4.078 0.592 - 680.8 1 2 0 0.0024 21 0 0 0 8.96E+07 0.00E+00 - - - 8.5094 0.9958 221125_WJC_METTL3_EV_vs_WT_F04.18636.18636.3 0.0339 13/64 K.ELTDEEAER[166.11]LQLEIDQK[136.11].K "sp|Q9Y266|NUDC_HUMAN,tr|A0A0A0MSS4|A0A0A0MSS4_HUMAN,tr|A0A0A0MSU9|A0A0A0MSU9_HUMAN" 3 2076.0342 1.64 52110 18636 3 2076.031104 693.0187 Nuclear migration protein nudC OS=Homo sapiens OX=9606 GN=NUDC PE=1 SV=1 4 3135 - 553797 - - - -1.474 - 2.262 0.264 - 143.2 1 2 1 -0.0031 17 0 0 0 1.67E+07 1.02E+07 - - - 3.5446 0.9998 221125_WJC_METTL3_EV_vs_WT_F04.18637.18637.3 4.75E-05 Dec-64 K.LIKDDFLQQNGYTPYDR.F sp|P38606|VATA_HUMAN 1 2085.0167 1.34 52111 18637 3 2085.018229 696.0128 V-type proton ATPase catalytic subunit A OS=Homo sapiens OX=9606 GN=ATP6V1A PE=1 SV=2 4.43 3135.1 - 379823 - - - 0.7237 - 2.277 0.492 - 190.6 1 2 1 0.0015 17 0 0 0 7.13E+06 5.33E+06 - - - 6.1037 0.9998 221125_WJC_METTL3_EV_vs_WT_F04.18642.18642.3 0.00229 Dec-44 R.QLFHPEQLITGK.E "sp|Q9NY65|TBA8_HUMAN,sp|Q6PEY2|TBA3E_HUMAN,sp|P0DPH7|TBA3C_HUMAN,sp|Q71U36|TBA1A_HUMAN,sp|P0DPH8|TBA3D_HUMAN,sp|Q9H853|TBA4B_HUMAN,sp|P68366|TBA4A_HUMAN,sp|P68363|TBA1B_HUMAN,sp|Q9BQE3|TBA1C_HUMAN,tr|C9JJQ8|C9JJQ8_HUMAN,tr|F8VS66|F8VS66_HUMAN,tr|F8VWV9|F8VWV9_HUMAN,tr|F8VRZ4|F8VRZ4_HUMAN,tr|F8VVB9|F8VVB9_HUMAN,tr|C9JQ00|C9JQ00_HUMAN,tr|C9JEV8|C9JEV8_HUMAN,tr|A0A7P0TA31|A0A7P0TA31_HUMAN,tr|A0A1W2PQM2|A0A1W2PQM2_HUMAN,tr|F5H5D3|F5H5D3_HUMAN,tr|C9J2C0|C9J2C0_HUMAN,tr|C9K0S6|C9K0S6_HUMAN,tr|C9JDL2|C9JDL2_HUMAN,tr|F8VQQ4|F8VQQ4_HUMAN,tr|F8VX09|F8VX09_HUMAN,tr|A0A7P0T945|A0A7P0T945_HUMAN" 25 1409.7667 0.56 52114 18642 3 1409.767704 470.9295 Tubulin alpha-8 chain OS=Homo sapiens OX=9606 GN=TUBA8 PE=1 SV=1 6.75 3135.7 - 1.97E+06 - - - 0.7122 - 2.175 0.361 - 208.7 1 2 0 0.001 12 0 0 0 9.42E+07 1.68E+08 - - - 4.7183 0.9972 221125_WJC_METTL3_EV_vs_WT_F04.18644.18644.3 4.39E-08 15/72 S.NVSSVPLPAENVTITAGQR.L "sp|Q14157|UBP2L_HUMAN,tr|F8W726|F8W726_HUMAN,tr|Q5VU77|Q5VU77_HUMAN" 3 1952.0327 0.13 52116 18644 3 1952.0358 651.6848 Ubiquitin-associated protein 2-like OS=Homo sapiens OX=9606 GN=UBAP2L PE=1 SV=2 6 3135.9 - 1.32E+06 - - - 1.586 - 2.648 0.564 - 215 1 1 0 0.0031 19 0 0 0 5.32E+07 4.08E+08 - - - 7.2196 0.995 221125_WJC_METTL3_EV_vs_WT_F04.18646.18646.2 0.434 20-Dec K.EKFEEMIQQIK.E "sp|P48643|TCPE_HUMAN,tr|E9PCA1|E9PCA1_HUMAN,tr|B7ZAR1|B7ZAR1_HUMAN,tr|E7ENZ3|E7ENZ3_HUMAN" 4 1421.7225 0.63 52118 18646 2 1421.720542 711.8685 T-complex protein 1 subunit epsilon OS=Homo sapiens OX=9606 GN=CCT5 PE=1 SV=1 4.79 3136.1 - 1.17E+06 - - - -1.3434 - 2.216 0.315 - 385.9 1 2 1 -0.0019 11 0 0 0 2.84E+07 4.55E+07 - - - 3.5196 0.9998 221125_WJC_METTL3_EV_vs_WT_F04.18648.18648.3 1.71E-06 14/40 K.LKVPEWVDTVK.L "sp|P39019|RS19_HUMAN,tr|M0R140|M0R140_HUMAN,tr|M0R2L9|M0R2L9_HUMAN,tr|M0QYF7|M0QYF7_HUMAN" 4 1312.7391 1.21 52120 18648 3 1312.739368 438.587 40S ribosomal protein S19 OS=Homo sapiens OX=9606 GN=RPS19 PE=1 SV=2 6.07 3136.3 - 820875 - - - 0.2133 - 2.801 0.43 - 326.7 1 2 1 0.0003 11 0 0 0 6.79E+07 5.63E+07 - - - 6.26 1 221125_WJC_METTL3_EV_vs_WT_F04.18649.18649.3 6.77E-11 25/56 R.GVEK[136.11]PPHLAALILAR[166.11].G "sp|Q8NFW8|NEUA_HUMAN,tr|F5H296|F5H296_HUMAN" 2 1601.9736 0.83 52121 18649 3 1601.974662 534.9985 N-acylneuraminate cytidylyltransferase OS=Homo sapiens OX=9606 GN=CMAS PE=1 SV=2 8.75 3136.4 - 761055 - - - 0.6523 - 3.726 0.63 - 868.3 1 2 0 0.001 15 0 0 0 5.80E+06 6.99E+06 - - - 8.9958 0.9999 221125_WJC_METTL3_EV_vs_WT_F04.18655.18655.4 0.000872 Dec-84 R.GVEKPPHLAALILAR.G "sp|Q8NFW8|NEUA_HUMAN,tr|F5H296|F5H296_HUMAN" 2 1583.9511 0.92 52127 18655 4 1583.950019 396.9951 N-acylneuraminate cytidylyltransferase OS=Homo sapiens OX=9606 GN=CMAS PE=1 SV=2 8.75 3137.2 - 260098 - - - -0.7121 - 2.398 0.427 - 138.4 1 2 0 -0.0011 15 0 0 0 3.08E+06 3.34E+06 - - - 3.2552 1 221125_WJC_METTL3_EV_vs_WT_F04.18660.18660.3 1.91E-07 16/56 K.LVEALC[160.03]AEHQINLIK.V sp|P25398|RS12_HUMAN 1 1749.9447 1.77 52130 18660 3 1749.946844 584.3222 40S ribosomal protein S12 OS=Homo sapiens OX=9606 GN=RPS12 PE=1 SV=3 5.4 3137.8 - 1.91E+06 - - - 1.2018 - 3.203 0.53 - 211.7 1 2 0 0.0021 15 0 0 0 2.53E+07 1.43E+07 - - - 7.4859 1 221125_WJC_METTL3_EV_vs_WT_F04.18662.18662.2 8.37E-09 17/30 K.QEETAVLEEDSADWEK.E sp|Q96A49|SYAP1_HUMAN 1 1877.8167 1.44 52132 18662 2 1877.819993 939.9156 Synapse-associated protein 1 OS=Homo sapiens OX=9606 GN=SYAP1 PE=1 SV=1 3.71 3137.9 - 981606 - - - 1.7627 - 3.507 0.683 - 1028.5 1 2 0 0.0033 16 0 0 0 1.07E+08 7.45E+07 - - - 7.1695 0.9999 221125_WJC_METTL3_EV_vs_WT_F04.18663.18663.3 2.76E-08 17/60 R.VEK[136.11]IPGGIIEDSC[160.03]VLR[166.11].G "sp|P49368|TCPG_HUMAN,tr|E9PRC8|E9PRC8_HUMAN,tr|B4DUR8|B4DUR8_HUMAN,tr|E9PQ35|E9PQ35_HUMAN,tr|Q5SZX6|Q5SZX6_HUMAN" 5 1801.9727 0.64 52133 18663 3 1801.975156 601.6648 T-complex protein 1 subunit gamma OS=Homo sapiens OX=9606 GN=CCT3 PE=1 SV=4 4.68 3138.1 - 737805 - - - 1.3685 - 3.068 0.545 - 426.2 1 2 1 0.0025 16 0 0 0 1.21E+07 1.89E+07 - - - 7.4919 0.9997 221125_WJC_METTL3_EV_vs_WT_F04.18666.18666.3 0.00106 Aug-72 R.IALTGGAALVADYGHDGTK[136.11].T "sp|Q7L592|NDUF7_HUMAN,tr|C9JS27|C9JS27_HUMAN,tr|C9J236|C9J236_HUMAN" 3 1836.9461 0.48 52136 18666 3 1836.948884 613.3227 "Protein arginine methyltransferase NDUFAF7, mitochondrial OS=Homo sapiens OX=9606 GN=NDUFAF7 PE=1 SV=1" 5.21 3138.4 - 355947 - - - 1.5009 - 2.345 0.386 - 51.2 4 2 0 0.0028 19 0 0 0 1.26E+06 2.61E+06 - - - 4.658 1 221125_WJC_METTL3_EV_vs_WT_F04.18667.18667.2 7.55E-09 13/26 K.EEYITSALESTEEK.L "sp|P52732|KIF11_HUMAN,tr|A0A7I2YQY4|A0A7I2YQY4_HUMAN,tr|A0A7I2V3A9|A0A7I2V3A9_HUMAN,tr|A0A7I2V3V3|A0A7I2V3V3_HUMAN" 4 1627.7465 4.8 52137 18667 2 1627.740555 814.8805 Kinesin-like protein KIF11 OS=Homo sapiens OX=9606 GN=KIF11 PE=1 SV=2 3.98 3138.6 - 298413 - - - -3.6388 - 2.78 0.62 - 404.5 1 2 0 -0.0059 14 0 0 0 4.43E+08 9.23E+07 - - - 6.1842 1 221125_WJC_METTL3_EV_vs_WT_F04.18672.18672.2 6.81E-10 19/36 S.NVSSVPLPAENVTITAGQR.L "sp|Q14157|UBP2L_HUMAN,tr|F8W726|F8W726_HUMAN,tr|Q5VU77|Q5VU77_HUMAN" 3 1952.0327 0.04 52140 18672 2 1952.035338 977.0236 Ubiquitin-associated protein 2-like OS=Homo sapiens OX=9606 GN=UBAP2L PE=1 SV=2 6 3139.1 - 1.21E+06 - - - 1.3494 - 3.006 0.654 - 593.7 1 1 0 0.0026 19 0 0 0 2.07E+07 5.39E+08 - - - 6.5765 1 221125_WJC_METTL3_EV_vs_WT_F04.18673.18673.3 3.06E-09 14/60 R.DMLGGNGISDEYHVIR[166.11].H "sp|Q92947|GCDH_HUMAN,tr|K7ESA6|K7ESA6_HUMAN,tr|K7EQ99|K7EQ99_HUMAN" 3 1784.8391 0.96 52141 18673 3 1784.840279 595.9536 "Glutaryl-CoA dehydrogenase, mitochondrial OS=Homo sapiens OX=9606 GN=GCDH PE=1 SV=1" 4.54 3139.2 - 1.39E+06 - - - 0.6589 - 2.726 0.668 - 206 1 2 0 0.0012 16 0 0 0 1.08E+07 1.13E+07 - - - 8.5604 0.9999 221125_WJC_METTL3_EV_vs_WT_F04.18674.18674.3 2.83E-07 16/60 R.DMLGGNGISDEYHVIR.H "sp|Q92947|GCDH_HUMAN,tr|K7ESA6|K7ESA6_HUMAN,tr|K7EQ99|K7EQ99_HUMAN" 3 1774.8308 0.94 52142 18674 3 1774.836969 592.6176 "Glutaryl-CoA dehydrogenase, mitochondrial OS=Homo sapiens OX=9606 GN=GCDH PE=1 SV=1" 4.54 3139.3 - 1.40E+06 - - - 3.4572 - 3.071 0.6 - 310.6 1 2 0 0.0061 16 0 0 0 1.05E+07 1.12E+07 - - - 8.1066 0.9999 221125_WJC_METTL3_EV_vs_WT_F04.18675.18675.3 3.68E-07 Dec-44 R.EHALLAYTLGVK[136.11].Q "sp|Q05639|EF1A2_HUMAN,sp|P68104|EF1A1_HUMAN,sp|Q5VTE0|EF1A3_HUMAN,tr|A0A2R8Y488|A0A2R8Y488_HUMAN,tr|A0A7I2V659|A0A7I2V659_HUMAN,tr|A0A7I2V3H3|A0A7I2V3H3_HUMAN,tr|A0A2U3TZH3|A0A2U3TZH3_HUMAN,tr|A0A7I2V5N4|A0A7I2V5N4_HUMAN,tr|A0A087WVQ9|A0A087WVQ9_HUMAN,tr|A0A087WV01|A0A087WV01_HUMAN,tr|A0A2R8Y660|A0A2R8Y660_HUMAN" 11 1321.7485 3.11 52143 18675 3 1321.750682 441.5901 Elongation factor 1-alpha 2 OS=Homo sapiens OX=9606 GN=EEF1A2 PE=1 SV=1 6.85 3139.4 - 1.04E+06 - - - 1.6229 - 2.646 0.401 - 216 1 2 0 0.0021 12 0 0 0 7.72E+07 2.48E+07 - - - 5.7073 0.9995 221125_WJC_METTL3_EV_vs_WT_F04.18676.18676.3 0.194 Nov-48 K.SEDFSLPAYMDRR.D "sp|P13073|COX41_HUMAN,tr|H3BNI5|H3BNI5_HUMAN,tr|Q86WV2|Q86WV2_HUMAN,tr|H3BN72|H3BN72_HUMAN,tr|H3BNV9|H3BNV9_HUMAN" 5 1585.7195 0.89 52144 18676 3 1585.722002 529.5804 "Cytochrome c oxidase subunit 4 isoform 1, mitochondrial OS=Homo sapiens OX=9606 GN=COX4I1 PE=1 SV=1" 4.56 3139.4 - 1.02E+06 - - - 1.5829 - 1.983 0.339 - 192.9 1 2 0 0.0025 13 0 0 0 1.44E+07 1.63E+07 - - - 4.175 0.9978 221125_WJC_METTL3_EV_vs_WT_F04.18679.18679.3 0.00047 13/64 K.LIK[136.11]DDFLQQNGYTPYDR[166.11].F sp|P38606|VATA_HUMAN 1 2103.0392 1.5 52147 18679 3 2103.047774 702.0203 V-type proton ATPase catalytic subunit A OS=Homo sapiens OX=9606 GN=ATP6V1A PE=1 SV=2 4.43 3139.8 - 620953 - - - 4.0817 - 2.637 0.429 - 236.2 1 2 1 0.0086 17 0 0 0 7.88E+06 5.27E+06 - - - 5.7702 1 221125_WJC_METTL3_EV_vs_WT_F04.18683.18683.3 2.95E-08 Dec-44 R.R[166.11]EDYYDIQLSIK[136.11].G "sp|Q93009|UBP7_HUMAN,tr|A0A669KBL1|A0A669KBL1_HUMAN,tr|F5H2X1|F5H2X1_HUMAN,tr|H3BND8|H3BND8_HUMAN" 4 1559.795 1.85 52151 18683 3 1559.794757 520.939 Ubiquitin carboxyl-terminal hydrolase 7 OS=Homo sapiens OX=9606 GN=USP7 PE=1 SV=2 4.56 3140.4 - 437516 - - - -0.1834 - 2.036 0.666 - 188.9 1 2 0 -0.0003 12 0 0 0 7.24E+06 3.92E+06 - - - 7.9359 0.9212 221125_WJC_METTL3_EV_vs_WT_F04.18686.18686.2 0.0286 May-38 G.EADGAGEAGEAGETAPEDEK.K sp|P35499|SCN4A_HUMAN 1 1931.7868 999 52154 18686 2 1931.7843 966.9007 Sodium channel protein type 4 subunit alpha OS=Homo sapiens OX=9606 GN=SCN4A PE=1 SV=4 3.67 3140.8 - 175985 - - - -1.3143 - 1.214 0.384 - 34.1 1 1 0 -0.0025 20 0 0 0 2.13E+06 0.00E+00 - - - 2.3532 0.9999 221125_WJC_METTL3_EV_vs_WT_F04.18691.18691.3 1.93E-07 13/60 K.QEETAVLEEDSADWEK.E sp|Q96A49|SYAP1_HUMAN 1 1877.8167 1.55 52157 18691 3 1877.821094 626.9462 Synapse-associated protein 1 OS=Homo sapiens OX=9606 GN=SYAP1 PE=1 SV=1 3.71 3141.4 - 3.44E+06 - - - 2.349 - 2.541 0.512 - 310.1 1 2 0 0.0044 16 0 0 0 4.07E+07 2.62E+07 - - - 6.6399 0.9999 221125_WJC_METTL3_EV_vs_WT_F04.18692.18692.3 4.08E-05 Nov-52 K.EEYITSALESTEEK.L "sp|P52732|KIF11_HUMAN,tr|A0A7I2YQY4|A0A7I2YQY4_HUMAN,tr|A0A7I2V3A9|A0A7I2V3A9_HUMAN,tr|A0A7I2V3V3|A0A7I2V3V3_HUMAN" 4 1627.7465 7.23 52158 18692 3 1627.748588 543.5894 Kinesin-like protein KIF11 OS=Homo sapiens OX=9606 GN=KIF11 PE=1 SV=2 3.98 3141.4 - 1.29E+06 - - - 1.2963 - 2.296 0.432 - 153.1 1 2 0 0.0021 14 0 0 0 7.76E+07 1.07E+07 - - - 5.5646 0.9988 221125_WJC_METTL3_EV_vs_WT_F04.18693.18693.3 0.000613 Dec-76 R.FSGVPDRFSGSGSGTDFTLK.L "sp|A2NJV5|KV229_HUMAN,sp|A0A075B6S2|KVD29_HUMAN,sp|A0A0A0MRZ7|KVD26_HUMAN" 3 2060.9803 999 52159 18693 3 2060.985159 688.0007 Immunoglobulin kappa variable 2-29 OS=Homo sapiens OX=9606 GN=IGKV2-29 PE=3 SV=2 5.96 3141.5 - 3.43E+06 - - - 2.3411 - 2.2 0.42 - 131.7 1 2 1 0.0048 20 0 0 0 8.91E+07 0.00E+00 - - - 5.1341 1 221125_WJC_METTL3_EV_vs_WT_F04.18694.18694.3 2.30E-10 16/56 K.R[166.11]LDEYTQEEIDAFPR[166.11].L "sp|Q9BYD1|RM13_HUMAN,tr|E5RJI7|E5RJI7_HUMAN,tr|H0YAX3|H0YAX3_HUMAN" 3 1900.907 1.02 52160 18694 3 1900.905235 634.6429 "39S ribosomal protein L13, mitochondrial OS=Homo sapiens OX=9606 GN=MRPL13 PE=1 SV=1" 4.18 3141.6 - 648808 - - - -0.9269 - 3.665 0.601 - 513.6 1 2 0 -0.0018 15 0 0 0 1.40E+07 1.38E+07 - - - 8.6292 1 221125_WJC_METTL3_EV_vs_WT_F04.18695.18695.2 6.13E-11 16/28 K.MPDFNSQAQSNLLGK.C sp|P50219|MNX1_HUMAN 1 1648.7879 1.76 52161 18695 2 1648.789203 825.4012 Motor neuron and pancreas homeobox protein 1 OS=Homo sapiens OX=9606 GN=MNX1 PE=1 SV=3 5.59 3141.7 - 619132 - - - 0.7866 - 3.437 0.672 - 819.4 1 2 0 0.0013 15 0 0 0 5.91E+06 3.35E+06 - - - 7.0393 0.983 221125_WJC_METTL3_EV_vs_WT_F04.18701.18701.3 0.117 Sep-40 K.HEYWFAVPQER[166.11].T "sp|Q8N573|OXR1_HUMAN,tr|H0YC07|H0YC07_HUMAN" 2 1470.692 1.06 52167 18701 3 1470.691446 491.2379 Oxidation resistance protein 1 OS=Homo sapiens OX=9606 GN=OXR1 PE=1 SV=2 5.4 3142.4 - 256973 - - - -0.3556 - 1.409 0.177 - 61.7 1 2 0 -0.0005 11 0 0 0 3.66E+06 3.46E+06 - - - 1.4873 0.9361 221125_WJC_METTL3_EV_vs_WT_F04.18703.18703.2 6.51E-06 Sep-34 R.FSGVPDRFSGSGSGTDFT.L "sp|A2NJV5|KV229_HUMAN,sp|A0A075B6S2|KVD29_HUMAN,sp|A0A0A0MRZ7|KVD26_HUMAN" 3 1819.8013 999 52169 18703 2 1819.80061 910.9079 Immunoglobulin kappa variable 2-29 OS=Homo sapiens OX=9606 GN=IGKV2-29 PE=3 SV=2 4.21 3142.7 - 196383 - - - -0.383 - 1.76 0.648 - 154 1 1 1 -0.0007 18 0 0 0 1.69E+06 0.00E+00 - - - 5.2168 1 221125_WJC_METTL3_EV_vs_WT_F04.18704.18704.3 4.19E-06 Nov-44 R.KGSLADVVDTLK.Q "sp|P35712|SOX6_HUMAN,sp|P35711|SOX5_HUMAN,tr|F5H876|F5H876_HUMAN,tr|F5H0I3|F5H0I3_HUMAN,tr|E9PQL4|E9PQL4_HUMAN,tr|G3V0H1|G3V0H1_HUMAN,tr|F5GWL1|F5GWL1_HUMAN,tr|E9PQ78|E9PQ78_HUMAN,tr|A0A2R8Y7P3|A0A2R8Y7P3_HUMAN,tr|E9PN02|E9PN02_HUMAN,tr|I3L0A5|I3L0A5_HUMAN,tr|A0A590UJ80|A0A590UJ80_HUMAN" 12 1244.6976 1.16 52170 18704 3 1244.698595 415.9065 Transcription factor SOX-6 OS=Homo sapiens OX=9606 GN=SOX6 PE=1 SV=3 5.96 3142.8 - 184678 - - - 0.7857 - 2.399 0.459 - 302.7 1 2 0 0.001 12 0 0 0 1.60E+06 1.38E+06 - - - 6.0826 0.8685 221125_WJC_METTL3_EV_vs_WT_F04.18705.18705.2 0.000372 26-Nov K.SQSSSAEQSFLFSR.E sp|Q9Y6D9|MD1L1_HUMAN 1 1559.7216 1.97 52171 18705 2 1561.728185 780.8681 Mitotic spindle assembly checkpoint protein MAD1 OS=Homo sapiens OX=9606 GN=MAD1L1 PE=1 SV=2 5.72 3143 - 169755 - - - 1286.502 - 1.86 0.445 - 306.3 1 2 0 2.0066 14 0 0 0 3.31E+07 1.68E+07 - - - 3.255 1 221125_WJC_METTL3_EV_vs_WT_F04.18711.18711.3 8.76E-05 Dec-44 K.FNSLNELVDYHR[166.11].S sp|P62993|GRB2_HUMAN 1 1515.7346 0.88 52176 18711 3 1515.736632 506.2521 Growth factor receptor-bound protein 2 OS=Homo sapiens OX=9606 GN=GRB2 PE=1 SV=1 5.32 3143.7 - 901718 - - - 1.3657 - 2.529 0.496 - 154.5 1 2 0 0.0021 12 0 0 0 5.14E+06 5.84E+06 - - - 6.6411 0.9997 221125_WJC_METTL3_EV_vs_WT_F04.18712.18712.3 0.000128 16/56 R.FK[136.11]EQLTPSQIMSLEK[136.11].E "sp|Q00059|TFAM_HUMAN,tr|H7BYN3|H7BYN3_HUMAN" 2 1793.9568 1.11 52177 18712 3 1793.960213 598.9929 "Transcription factor A, mitochondrial OS=Homo sapiens OX=9606 GN=TFAM PE=1 SV=1" 6.14 3143.8 - 871080 - - - 1.8902 - 3.332 0.425 - 406 1 2 1 0.0034 15 0 0 0 2.74E+07 2.47E+07 - - - 6.418 0.989 221125_WJC_METTL3_EV_vs_WT_F04.18713.18713.3 0.000319 14/72 K.VNGNPHSTPVSGPPAFLTQ.G sp|Q96I24|FUBP3_HUMAN 1 1918.9537 - 52178 18713 3 1918.956595 640.6585 Far upstream element-binding protein 3 OS=Homo sapiens OX=9606 GN=FUBP3 PE=1 SV=2 6.71 3143.9 - 716566 - - - 1.4951 - 2.942 0.386 - 166.1 1 1 0 0.0029 19 0 0 0 - - - - - 5.4938 1 221125_WJC_METTL3_EV_vs_WT_F04.18714.18714.2 1.23E-08 15/26 K.APNYSC[160.03]VMTGSWDK[136.11].T "sp|P78406|RAE1L_HUMAN,tr|E9PQ57|E9PQ57_HUMAN,tr|E9PPG9|E9PPG9_HUMAN" 3 1622.6949 1.45 52179 18714 2 1622.694922 812.3547 mRNA export factor OS=Homo sapiens OX=9606 GN=RAE1 PE=1 SV=1 5.87 3144 - 657609 - - - 0.0357 - 3.199 0.638 - 957.4 1 2 0 0.0001 14 0 0 0 2.41E+07 1.66E+07 - - - 6.6713 0.7822 221125_WJC_METTL3_EV_vs_WT_F04.18715.18715.2 9.71E-07 13/28 K.MPDFNSQAQSNLLGK[136.11].C sp|P50219|MNX1_HUMAN 1 1656.8021 1.76 52180 18715 2 1657.794019 829.4083 Motor neuron and pancreas homeobox protein 1 OS=Homo sapiens OX=9606 GN=MNX1 PE=1 SV=3 5.59 3144.1 - 478687 - - - 598.6913 - 2.641 0.571 - 505.3 1 2 0 0.9919 15 0 0 0 5.91E+06 3.35E+06 - - - 5.3346 1 221125_WJC_METTL3_EV_vs_WT_F04.18716.18716.3 4.81E-08 17/60 R.DALR[166.11]PPLQNINSVQLK[136.11].E sp|Q14008|CKAP5_HUMAN 1 1823.0384 0.84 52181 18716 3 1823.038794 608.6867 Cytoskeleton-associated protein 5 OS=Homo sapiens OX=9606 GN=CKAP5 PE=1 SV=3 8.75 3144.3 - 476452 - - - 0.215 - 3.282 0.574 - 549.8 1 2 0 0.0004 16 0 0 0 4.18E+06 4.95E+06 - - - 7.9888 1 221125_WJC_METTL3_EV_vs_WT_F04.18718.18718.2 1.16E-11 15/32 K.MSASDPNSSIFLTDTAK[136.11].Q "sp|P23381|SYWC_HUMAN,tr|H0YJP3|H0YJP3_HUMAN" 2 1791.844 0.52 52183 18718 2 1791.845197 896.9293 "Tryptophan--tRNA ligase, cytoplasmic OS=Homo sapiens OX=9606 GN=WARS1 PE=1 SV=2" 4.21 3144.5 - 408452 - - - 0.6513 - 3.185 0.723 - 616.3 1 2 0 0.0012 17 0 0 0 2.27E+06 4.34E+06 - - - 7.2288 0.9986 221125_WJC_METTL3_EV_vs_WT_F04.18720.18720.2 5.80E-09 26-Dec R.EAQQQQLQALIAEK.K "sp|Q8IY31|IFT20_HUMAN,tr|J3QRC6|J3QRC6_HUMAN,tr|J3QR43|J3QR43_HUMAN" 3 1596.8471 4.09 52185 18720 2 1596.85259 799.4308 Intraflagellar transport protein 20 homolog OS=Homo sapiens OX=9606 GN=IFT20 PE=1 SV=1 4.53 3144.8 - 322194 - - - 3.4161 - 2.7 0.324 - 540.2 1 2 0 0.0055 14 0 0 0 2.89E+06 7.08E+05 - - - 3.9249 0.9852 221125_WJC_METTL3_EV_vs_WT_F04.18721.18721.2 1.37E-08 Nov-36 K.VNGNPHSTPVSGPPAFLTQ.G sp|Q96I24|FUBP3_HUMAN 1 1918.9537 - 52186 18721 2 1918.958267 960.4841 Far upstream element-binding protein 3 OS=Homo sapiens OX=9606 GN=FUBP3 PE=1 SV=2 6.71 3144.9 - 251473 - - - 2.3664 - 2.62 0.571 - 230.5 1 1 0 0.0045 19 0 0 0 - - - - - 5.625 0.9997 221125_WJC_METTL3_EV_vs_WT_F04.18722.18722.2 1.87E-06 15/32 R.ALLEAGALPNAPNSYGR.R "sp|P42771|CDN2A_HUMAN,tr|J3QRG6|J3QRG6_HUMAN" 2 1712.8846 4.82 52187 18722 2 1712.888764 857.4496 Cyclin-dependent kinase inhibitor 2A OS=Homo sapiens OX=9606 GN=CDKN2A PE=1 SV=2 6.05 3145 - 249251 - - - 2.4409 - 3.157 0.492 - 417.2 1 2 0 0.0042 17 0 0 0 2.22E+06 4.61E+05 - - - 5.5 1 221125_WJC_METTL3_EV_vs_WT_F04.18726.18726.3 1.52E-07 15/60 K.QEETAVLEEDSADWEK[136.11].E sp|Q96A49|SYAP1_HUMAN 1 1885.8309 1.55 52189 18726 3 1885.832027 629.6176 Synapse-associated protein 1 OS=Homo sapiens OX=9606 GN=SYAP1 PE=1 SV=1 3.71 3145.6 - 3.58E+06 - - - 0.6066 - 2.987 0.588 - 460.3 1 2 0 0.0011 16 0 0 0 4.07E+07 2.62E+07 - - - 7.903 1 221125_WJC_METTL3_EV_vs_WT_F04.18727.18727.3 8.12E-12 25/76 R.NLALC[160.03]PANHAPLQEAAVIPR.L sp|P14923|PLAK_HUMAN 1 2154.1368 416.85 52190 18727 3 2154.138748 719.0529 Junction plakoglobin OS=Homo sapiens OX=9606 GN=JUP PE=1 SV=3 6.74 3145.7 - 3.91E+06 - - - 0.908 - 4.279 0.675 - 715.2 1 2 0 0.002 20 0 0 0 3.43E+07 8.22E+04 - - - 9.5918 1 221125_WJC_METTL3_EV_vs_WT_F04.18728.18728.2 5.04E-07 18/30 K.QEETAVLEEDSADWEK[136.11].E sp|Q96A49|SYAP1_HUMAN 1 1885.8309 1.44 52191 18728 2 1885.830979 943.9227 Synapse-associated protein 1 OS=Homo sapiens OX=9606 GN=SYAP1 PE=1 SV=1 3.71 3145.7 - 7.56E+06 - - - 0.0509 - 3.367 0.647 - 1128 1 2 0 0.0001 16 0 0 0 1.07E+08 7.45E+07 - - - 6.8044 1 221125_WJC_METTL3_EV_vs_WT_F04.18729.18729.2 5.25E-07 26-Nov K.APNYSC[160.03]VMTGSWDK.T "sp|P78406|RAE1L_HUMAN,tr|E9PQ57|E9PQ57_HUMAN,tr|E9PPG9|E9PPG9_HUMAN" 3 1614.6807 1.45 52192 18729 2 1614.680704 808.3476 mRNA export factor OS=Homo sapiens OX=9606 GN=RAE1 PE=1 SV=1 5.87 3145.8 - 2.12E+06 - - - 0.0248 - 2.709 0.685 - 394.6 1 2 0 0 14 0 0 0 2.41E+07 1.66E+07 - - - 6.6013 0.9999 221125_WJC_METTL3_EV_vs_WT_F04.18730.18730.2 6.30E-05 20-Dec K.SNQQLVDIIEK.V "sp|P61289|PSME3_HUMAN,tr|K7ENH2|K7ENH2_HUMAN,tr|B3KQ25|B3KQ25_HUMAN,tr|K7ESG5|K7ESG5_HUMAN,tr|K9J957|K9J957_HUMAN,tr|K7EMD0|K7EMD0_HUMAN,tr|K7EKR3|K7EKR3_HUMAN,tr|K7EPX6|K7EPX6_HUMAN" 8 1285.6878 1.19 52193 18730 2 1285.689275 643.8512 Proteasome activator complex subunit 3 OS=Homo sapiens OX=9606 GN=PSME3 PE=1 SV=1 4.37 3145.9 - 2.04E+06 - - - 1.162 - 2.677 0.482 - 807.3 1 2 0 0.0015 11 0 0 0 1.74E+07 1.46E+07 - - - 5.2644 1 221125_WJC_METTL3_EV_vs_WT_F04.18731.18731.2 3.21E-09 16/22 R.QLFHPEQLITGK[136.11].E "sp|Q9NY65|TBA8_HUMAN,sp|Q6PEY2|TBA3E_HUMAN,sp|P0DPH7|TBA3C_HUMAN,sp|Q71U36|TBA1A_HUMAN,sp|P0DPH8|TBA3D_HUMAN,sp|Q9H853|TBA4B_HUMAN,sp|P68366|TBA4A_HUMAN,sp|P68363|TBA1B_HUMAN,sp|Q9BQE3|TBA1C_HUMAN,tr|C9JJQ8|C9JJQ8_HUMAN,tr|F8VS66|F8VS66_HUMAN,tr|F8VWV9|F8VWV9_HUMAN,tr|F8VRZ4|F8VRZ4_HUMAN,tr|F8VVB9|F8VVB9_HUMAN,tr|C9JQ00|C9JQ00_HUMAN,tr|C9JEV8|C9JEV8_HUMAN,tr|A0A7P0TA31|A0A7P0TA31_HUMAN,tr|A0A1W2PQM2|A0A1W2PQM2_HUMAN,tr|F5H5D3|F5H5D3_HUMAN,tr|C9J2C0|C9J2C0_HUMAN,tr|C9K0S6|C9K0S6_HUMAN,tr|C9JDL2|C9JDL2_HUMAN,tr|F8VQQ4|F8VQQ4_HUMAN,tr|F8VX09|F8VX09_HUMAN,tr|A0A7P0T945|A0A7P0T945_HUMAN" 25 1417.7809 0.58 52194 18731 2 1417.781764 709.8977 Tubulin alpha-8 chain OS=Homo sapiens OX=9606 GN=TUBA8 PE=1 SV=1 6.75 3146 - 1.50E+06 - - - 0.6094 - 3.069 0.58 - 1041.3 1 2 0 0.0009 12 0 0 0 1.32E+07 2.30E+07 - - - 6.2751 1 221125_WJC_METTL3_EV_vs_WT_F04.18734.18734.3 4.98E-09 15/52 K.HTLSIGDMVTGTVK[136.11].S "sp|Q14690|RRP5_HUMAN,tr|A0A3B3IUD7|A0A3B3IUD7_HUMAN" 2 1465.769 0.48 52197 18734 3 1465.769742 489.5969 Protein RRP5 homolog OS=Homo sapiens OX=9606 GN=PDCD11 PE=1 SV=3 6.74 3146.3 - 661955 - - - 0.496 - 3.085 0.573 - 391.4 1 2 0 0.0007 14 0 0 0 3.22E+06 6.73E+06 - - - 7.922 0.9993 221125_WJC_METTL3_EV_vs_WT_F04.18735.18735.3 0.0167 Dec-44 K.FNSLNELVDYHR.S sp|P62993|GRB2_HUMAN 1 1505.7263 0.57 52198 18735 3 1505.728831 502.916 Growth factor receptor-bound protein 2 OS=Homo sapiens OX=9606 GN=GRB2 PE=1 SV=1 5.32 3146.4 - 642550 - - - 1.6862 - 2.154 0.293 - 143.2 1 2 0 0.0025 12 0 0 0 5.39E+06 9.44E+06 - - - 3.9329 0.7987 221125_WJC_METTL3_EV_vs_WT_F04.18737.18737.3 2.80E-07 15/76 K.AEAESLYQSKYEELQITAGR.H sp|P04264|K2C1_HUMAN 1 2285.1176 999 52200 18737 3 2286.102807 762.7131 "Keratin, type II cytoskeletal 1 OS=Homo sapiens OX=9606 GN=KRT1 PE=1 SV=6" 4.49 3146.7 - 331855 - - - 431.1599 - 2.705 0.586 - 299.5 1 2 1 0.9853 20 0 0 0 1.56E+06 0.00E+00 - - - 7.2145 0.9995 221125_WJC_METTL3_EV_vs_WT_F04.18738.18738.3 0.00033 Oct-36 K.DNDTLKDLLK.A sp|Q9H8Y8|GORS2_HUMAN 1 1173.6241 1.45 52201 18738 3 1173.624479 392.2153 Golgi reassembly-stacking protein 2 OS=Homo sapiens OX=9606 GN=GORASP2 PE=1 SV=3 4.43 3146.8 - 300508 - - - 0.3076 - 2.144 0.394 - 120 1 2 1 0.0004 10 0 0 0 2.41E+06 1.66E+06 - - - 5.1599 0.9941 221125_WJC_METTL3_EV_vs_WT_F04.18739.18739.3 0.00859 Jul-36 K.DNDTLK[136.11]DLLK[136.11].A sp|Q9H8Y8|GORS2_HUMAN 1 1189.6525 1.45 52202 18739 3 1189.654026 397.5581 Golgi reassembly-stacking protein 2 OS=Homo sapiens OX=9606 GN=GORASP2 PE=1 SV=3 4.43 3146.9 - 240168 - - - 1.2676 - 1.44 0.331 - 61.6 1 2 1 0.0015 10 0 0 0 2.41E+06 1.66E+06 - - - 3.2948 0.9998 221125_WJC_METTL3_EV_vs_WT_F04.18740.18740.3 0.000395 15/44 K.TTISVAHLLAAR.Q "sp|Q8NCA5|FA98A_HUMAN,tr|E9PH82|E9PH82_HUMAN" 2 1251.7299 0.86 52203 18740 3 1251.733947 418.2506 Protein FAM98A OS=Homo sapiens OX=9606 GN=FAM98A PE=1 SV=2 9.44 3147.1 - 221879 - - - 3.2171 - 2.708 0.43 - 399.3 1 2 0 0.004 12 0 0 0 2.05E+06 2.40E+06 - - - 6.0943 0.9995 221125_WJC_METTL3_EV_vs_WT_F04.18741.18741.3 1.85E-05 Dec-52 K.THLPGFVEQAEALK[136.11].A sp|P30044|PRDX5_HUMAN 1 1546.8235 1.51 52204 18741 3 1546.827252 516.6151 "Peroxiredoxin-5, mitochondrial OS=Homo sapiens OX=9606 GN=PRDX5 PE=1 SV=4" 5.37 3147.2 - 197447 - - - 2.4301 - 2.244 0.357 - 134.3 1 2 0 0.0038 14 0 0 0 2.69E+08 1.78E+08 - - - 4.6671 0.9996 221125_WJC_METTL3_EV_vs_WT_F04.18744.18744.3 1.81E-06 14/56 R.FKEQLTPSQIMSLEK.E "sp|Q00059|TFAM_HUMAN,tr|H7BYN3|H7BYN3_HUMAN" 2 1777.9284 0.7 52205 18744 3 1777.933172 593.6501 "Transcription factor A, mitochondrial OS=Homo sapiens OX=9606 GN=TFAM PE=1 SV=1" 6.14 3147.6 - 3.42E+06 - - - 2.6716 - 2.902 0.473 - 321.1 1 2 1 0.0047 15 0 0 0 2.72E+07 3.87E+07 - - - 6.5922 0.9998 221125_WJC_METTL3_EV_vs_WT_F04.18745.18745.3 4.16E-05 13/44 R.LLKEYQELMNVK.L "sp|P48668|K2C6C_HUMAN,sp|P04259|K2C6B_HUMAN,sp|P02538|K2C6A_HUMAN" 3 1506.8116 58.27 52206 18745 3 1506.813502 503.2778 "Keratin, type II cytoskeletal 6C OS=Homo sapiens OX=9606 GN=KRT6C PE=1 SV=3" 6.14 3147.7 - 1.17E+06 - - - 1.2616 - 2.454 0.478 - 215.6 1 2 1 0.0019 12 0 0 0 1.62E+07 2.78E+05 - - - 6.357 1 221125_WJC_METTL3_EV_vs_WT_F04.18746.18746.2 7.97E-09 26-Dec K.EEYITSALESTEEK[136.11].L "sp|P52732|KIF11_HUMAN,tr|A0A7I2YQY4|A0A7I2YQY4_HUMAN,tr|A0A7I2V3A9|A0A7I2V3A9_HUMAN,tr|A0A7I2V3V3|A0A7I2V3V3_HUMAN" 4 1635.7607 4.79 52207 18746 2 1635.760189 818.8876 Kinesin-like protein KIF11 OS=Homo sapiens OX=9606 GN=KIF11 PE=1 SV=2 3.98 3147.7 - 9.48E+06 - - - -0.2989 - 2.708 0.643 - 433.5 1 2 0 -0.0005 14 0 0 0 4.42E+08 9.23E+07 - - - 6.29 0.9999 221125_WJC_METTL3_EV_vs_WT_F04.18747.18747.2 2.27E-06 13/20 K.SNQQLVDIIEK[136.11].V "sp|P61289|PSME3_HUMAN,tr|K7ENH2|K7ENH2_HUMAN,tr|B3KQ25|B3KQ25_HUMAN,tr|K7ESG5|K7ESG5_HUMAN,tr|K9J957|K9J957_HUMAN,tr|K7EMD0|K7EMD0_HUMAN,tr|K7EKR3|K7EKR3_HUMAN,tr|K7EPX6|K7EPX6_HUMAN" 8 1293.702 1.19 52208 18747 2 1293.702603 647.8583 Proteasome activator complex subunit 3 OS=Homo sapiens OX=9606 GN=PSME3 PE=1 SV=1 4.37 3147.8 - 1.53E+06 - - - 0.4808 - 2.77 0.506 - 996.8 1 2 0 0.0006 11 0 0 0 1.74E+07 1.46E+07 - - - 5.5343 0.9999 221125_WJC_METTL3_EV_vs_WT_F04.18748.18748.3 0.000295 13/52 K.FNLTGLNEQVPHYR[166.11].Q "sp|P67870|CSK2B_HUMAN,tr|Q5SRQ3|Q5SRQ3_HUMAN,tr|A0A0G2JM58|A0A0G2JM58_HUMAN,tr|Q5SRQ6|Q5SRQ6_HUMAN,tr|N0E644|N0E644_HUMAN,tr|N0E472|N0E472_HUMAN,tr|A0A7I2YQ78|A0A7I2YQ78_HUMAN,tr|A0A7I2V500|A0A7I2V500_HUMAN,tr|A0A7I2YQQ2|A0A7I2YQQ2_HUMAN,tr|A0A0G2JM12|A0A0G2JM12_HUMAN" 10 1696.8561 1.29 52209 18748 3 1696.859848 566.626 Casein kinase II subunit beta OS=Homo sapiens OX=9606 GN=CSNK2B PE=1 SV=1 6.75 3147.9 - 1.21E+06 - - - 2.2241 - 2.427 0.458 - 191.3 1 2 0 0.0038 14 0 0 0 2.05E+07 1.59E+07 - - - 6.0015 0.9982 221125_WJC_METTL3_EV_vs_WT_F04.18750.18750.3 0.0141 13/76 K.TVEPPISQVGNVDTASELEK.G sp|O95104|SCAF4_HUMAN 1 2112.0586 1.17 52211 18750 3 2112.054499 705.0268 SR-related and CTD-associated factor 4 OS=Homo sapiens OX=9606 GN=SCAF4 PE=1 SV=3 4 3148.1 - 864113 - - - -1.9625 - 2.032 0.271 - 132.7 1 2 0 -0.0041 20 0 0 0 5.81E+06 4.97E+06 - - - 3.2803 1 221125_WJC_METTL3_EV_vs_WT_F04.18753.18753.3 8.80E-07 15/52 K.HTLSIGDMVTGTVK.S "sp|Q14690|RRP5_HUMAN,tr|A0A3B3IUD7|A0A3B3IUD7_HUMAN" 2 1457.7548 0.48 52214 18753 3 1457.755552 486.9255 Protein RRP5 homolog OS=Homo sapiens OX=9606 GN=PDCD11 PE=1 SV=3 6.74 3148.5 - 462975 - - - 0.5056 - 2.946 0.564 - 374.1 1 2 0 0.0007 14 0 0 0 3.22E+06 6.73E+06 - - - 7.6992 1 221125_WJC_METTL3_EV_vs_WT_F04.18754.18754.2 2.42E-12 16/36 K.TGAPQYGSYGTAPVNLNIK[136.11].T "sp|Q6UN15|FIP1_HUMAN,tr|A0A0B4J203|A0A0B4J203_HUMAN" 2 1957.9989 0.71 52215 18754 2 1957.99945 980.0067 Pre-mRNA 3'-end-processing factor FIP1 OS=Homo sapiens OX=9606 GN=FIP1L1 PE=1 SV=1 8.17 3148.6 - 453409 - - - 0.2855 - 3.001 0.721 - 510.2 1 2 0 0.0006 19 0 0 0 4.00E+06 5.65E+06 - - - 7.0679 1 221125_WJC_METTL3_EV_vs_WT_F04.18756.18756.2 8.75E-10 Nov-38 R.DC[160.03]GGAAQLAGPAAEADPLGR.F "sp|Q9Y508|RN114_HUMAN,tr|A0A096LNN8|A0A096LNN8_HUMAN,tr|A0A096LP02|A0A096LP02_HUMAN,tr|A0A096LNV3|A0A096LNV3_HUMAN,tr|A0A096LNT1|A0A096LNT1_HUMAN,tr|A0A096LPF9|A0A096LPF9_HUMAN" 6 1895.8796 4.38 52217 18756 2 1895.880739 948.9471 E3 ubiquitin-protein ligase RNF114 OS=Homo sapiens OX=9606 GN=RNF114 PE=1 SV=1 4.03 3148.9 - 229399 - - - 0.614 - 3.006 0.69 - 215.3 1 2 0 0.0012 20 0 0 0 3.50E+06 7.98E+05 - - - 6.8429 0.815 221125_WJC_METTL3_EV_vs_WT_F04.18761.18761.3 0.538 Apr-36 R.C[160.03]NMSLTHFFK[136.11].L sp|Q6L8Q7|PDE12_HUMAN 1 1291.5933 0.96 52222 18761 3 1291.592646 431.5384 "2',5'-phosphodiesterase 12 OS=Homo sapiens OX=9606 GN=PDE12 PE=1 SV=2" 8.23 3149.6 - 195675 - - - -0.5056 - 0.832 0.217 - 9.9 6 2 0 -0.0007 10 0 0 0 1.43E+06 1.48E+06 - - - 0.0619 0.9918 221125_WJC_METTL3_EV_vs_WT_F04.18764.18764.3 7.43E-07 14/52 Q.FNWYVDGVEVHNAK.T "sp|P01859|IGHG2_HUMAN,sp|P01861|IGHG4_HUMAN,sp|P01857|IGHG1_HUMAN,tr|A0A0A0MS08|A0A0A0MS08_HUMAN,tr|A0A286YFJ8|A0A286YFJ8_HUMAN,tr|A0A286YEY4|A0A286YEY4_HUMAN" 6 1676.7947 13.07 52223 18764 3 1676.798314 559.9388 Immunoglobulin heavy constant gamma 2 OS=Homo sapiens OX=9606 GN=IGHG2 PE=1 SV=2 5.32 3150 - 1.92E+06 - - - 2.1517 - 2.622 0.462 - 190.1 1 1 0 0.0036 14 0 0 0 1.95E+07 1.49E+06 - - - 6.2515 1 221125_WJC_METTL3_EV_vs_WT_F04.18766.18766.2 0.000386 14/26 K.SQSSSAEQSFLFSR.E sp|Q9Y6D9|MD1L1_HUMAN 1 1559.7216 1.97 52225 18766 2 1559.722994 780.8681 Mitotic spindle assembly checkpoint protein MAD1 OS=Homo sapiens OX=9606 GN=MAD1L1 PE=1 SV=2 5.72 3150.1 - 2.66E+06 - - - 0.8937 - 3.069 0.619 - 802.3 1 2 0 0.0014 14 0 0 0 3.31E+07 1.68E+07 - - - 6.4265 0.9996 221125_WJC_METTL3_EV_vs_WT_F04.18767.18767.3 4.00E-06 Dec-56 R.GPIK[136.11]FNVWDTAGQEK[136.11].F "sp|P62826|RAN_HUMAN,tr|H0YFC6|H0YFC6_HUMAN,tr|B5MDF5|B5MDF5_HUMAN,tr|J3KQE5|J3KQE5_HUMAN,tr|F5H018|F5H018_HUMAN" 5 1704.8806 1.41 52226 18767 3 1704.885123 569.3008 GTP-binding nuclear protein Ran OS=Homo sapiens OX=9606 GN=RAN PE=1 SV=3 6.07 3150.2 - 890081 - - - 2.6407 - 2.309 0.536 - 152.6 1 2 1 0.0045 15 0 0 0 9.98E+06 7.06E+06 - - - 6.6982 1 221125_WJC_METTL3_EV_vs_WT_F04.18768.18768.3 1.28E-08 17/68 K.FGQMLGSNMTEFHSQISK[136.11].S "sp|Q14204|DYHC1_HUMAN,tr|A0A7P0T8N2|A0A7P0T8N2_HUMAN,tr|A0A7P0T9C4|A0A7P0T9C4_HUMAN,tr|A0A7P0TBJ7|A0A7P0TBJ7_HUMAN,tr|A0A804HHY6|A0A804HHY6_HUMAN,tr|A0A7P0T9K2|A0A7P0T9K2_HUMAN,tr|A0A7P0TB64|A0A7P0TB64_HUMAN,tr|A0A2R8Y706|A0A2R8Y706_HUMAN,tr|A0A7P0T916|A0A7P0T916_HUMAN,tr|A0A7P0TB75|A0A7P0TB75_HUMAN,tr|A0A7P0T8W5|A0A7P0T8W5_HUMAN,tr|A0A7P0T9S3|A0A7P0T9S3_HUMAN,tr|A0A7P0TAF3|A0A7P0TAF3_HUMAN,tr|A0A7P0T9F1|A0A7P0T9F1_HUMAN,tr|A0A7P0TAW9|A0A7P0TAW9_HUMAN,tr|A0A2R8YGC7|A0A2R8YGC7_HUMAN,tr|A0A7P0TA13|A0A7P0TA13_HUMAN,tr|A0A7P0T934|A0A7P0T934_HUMAN,tr|A0A7P0TAV5|A0A7P0TAV5_HUMAN,tr|A0A7P0T9Y3|A0A7P0T9Y3_HUMAN,tr|A0A7P0T7V5|A0A7P0T7V5_HUMAN,tr|A0A7P0T9R4|A0A7P0T9R4_HUMAN,tr|A0A2R8Y5T0|A0A2R8Y5T0_HUMAN,tr|A0A7P0T990|A0A7P0T990_HUMAN,tr|A0A7P0T942|A0A7P0T942_HUMAN,tr|A0A2R8YFZ7|A0A2R8YFZ7_HUMAN,tr|A0A7P0T825|A0A7P0T825_HUMAN,tr|A0A2R8Y6H2|A0A2R8Y6H2_HUMAN,tr|A0A7P0TBC9|A0A7P0TBC9_HUMAN,tr|A0A7P0TAM4|A0A7P0TAM4_HUMAN" 30 2048.9539 1.04 52227 18768 3 2048.95812 683.9919 Cytoplasmic dynein 1 heavy chain 1 OS=Homo sapiens OX=9606 GN=DYNC1H1 PE=1 SV=5 6.75 3150.3 - 773275 - - - 2.044 - 3.423 0.567 - 339 1 2 0 0.0042 18 0 0 0 5.38E+06 5.18E+06 - - - 7.9244 0.9999 221125_WJC_METTL3_EV_vs_WT_F04.18769.18769.3 8.81E-05 Oct-52 K.SQSSSAEQSFLFSR.E sp|Q9Y6D9|MD1L1_HUMAN 1 1559.7216 0.94 52228 18769 3 1559.723947 520.9145 Mitotic spindle assembly checkpoint protein MAD1 OS=Homo sapiens OX=9606 GN=MAD1L1 PE=1 SV=2 5.72 3150.4 - 717558 - - - 1.5048 - 1.976 0.478 - 124.9 1 2 0 0.0023 14 0 0 0 3.70E+06 3.95E+06 - - - 5.6786 1 221125_WJC_METTL3_EV_vs_WT_F04.18773.18773.2 3.86E-13 18/36 K.GSLGGGFSSGGFSGGSFSR.G "sp|P13645|K1C10_HUMAN,tr|A0A1B0GVI3|A0A1B0GVI3_HUMAN" 2 1706.7649 999 52232 18773 2 1706.762718 854.3897 "Keratin, type I cytoskeletal 10 OS=Homo sapiens OX=9606 GN=KRT10 PE=1 SV=6" 9.75 3150.9 - 461955 - - - -1.2562 - 3.492 0.622 - 910.9 1 2 0 -0.0021 19 0 0 0 1.87E+07 0.00E+00 - - - 6.7088 0.9869 221125_WJC_METTL3_EV_vs_WT_F04.18775.18775.2 1.47E-06 14/22 R.LLKEYQELMNVK.L "sp|P48668|K2C6C_HUMAN,sp|P04259|K2C6B_HUMAN,sp|P02538|K2C6A_HUMAN" 3 1506.8116 -1 52234 18775 2 1506.818331 754.4131 "Keratin, type II cytoskeletal 6C OS=Homo sapiens OX=9606 GN=KRT6C PE=1 SV=3" 6.14 3151.2 - 388271 - - - 4.4664 - 2.478 0.554 - 480.9 1 2 1 0.0067 12 0 0 0 0.00E+00 0.00E+00 - - - 5.5184 0.9996 221125_WJC_METTL3_EV_vs_WT_F04.18782.18782.3 3.43E-05 15/60 R.SDLKAEALASAIASTK.V sp|Q9NVT9|ARMC1_HUMAN 1 1574.8516 3.57 52240 18782 3 1574.855223 525.9578 Armadillo repeat-containing protein 1 OS=Homo sapiens OX=9606 GN=ARMC1 PE=1 SV=1 5.79 3152.2 - 512787 - - - 2.331 - 2.743 0.471 - 325.2 1 2 1 0.0037 16 0 0 0 2.83E+06 7.93E+05 - - - 6.3793 1 221125_WJC_METTL3_EV_vs_WT_F04.18783.18783.3 9.43E-07 18/44 R.TTELQDELSHLR[166.11].S "sp|Q9H019|MFR1L_HUMAN,tr|E9PLD2|E9PLD2_HUMAN,tr|E9PPQ0|E9PPQ0_HUMAN,tr|E9PRK5|E9PRK5_HUMAN,tr|E9PPF9|E9PPF9_HUMAN,tr|C9JF50|C9JF50_HUMAN,tr|E9PLU1|E9PLU1_HUMAN" 7 1450.7291 2.8 52241 18783 3 1450.729271 484.5837 Mitochondrial fission regulator 1-like OS=Homo sapiens OX=9606 GN=MTFR1L PE=1 SV=2 4.65 3152.3 - 2.37E+06 - - - 0.0889 - 3.135 0.401 - 655.3 1 2 0 0.0001 12 0 0 0 6.78E+07 2.43E+07 - - - 6.1779 1 221125_WJC_METTL3_EV_vs_WT_F04.18784.18784.3 9.25E-07 Dec-60 R.HLASDAIINENYDYLK.G "sp|P52948|NUP98_HUMAN,tr|H7C3P6|H7C3P6_HUMAN" 2 1877.9159 0.46 52242 18784 3 1877.918217 626.9793 Nuclear pore complex protein Nup98-Nup96 OS=Homo sapiens OX=9606 GN=NUP98 PE=1 SV=4 4.54 3152.3 - 2.19E+06 - - - 1.2109 - 2.561 0.486 - 172.9 1 2 0 0.0023 16 0 0 0 2.63E+07 5.71E+07 - - - 6.3707 0.9997 221125_WJC_METTL3_EV_vs_WT_F04.18785.18785.2 9.75E-07 13/22 K.LNDLEDALQQAK.E sp|P04264|K2C1_HUMAN 1 1356.6885 367.84 52243 18785 2 1356.690327 679.3515 "Keratin, type II cytoskeletal 1 OS=Homo sapiens OX=9606 GN=KRT1 PE=1 SV=6" 4.03 3152.4 - 1.74E+06 - - - 1.34 - 2.644 0.33 - 711.2 1 2 0 0.0018 12 0 0 0 1.10E+09 2.98E+06 - - - 4.0361 1 221125_WJC_METTL3_EV_vs_WT_F04.18786.18786.3 2.18E-09 17/60 R.GLGHQVATDALVAMEK.A sp|Q9Y3I0|RTCB_HUMAN 1 1638.8399 1.32 52244 18786 3 1638.84203 547.2873 RNA-splicing ligase RtcB homolog OS=Homo sapiens OX=9606 GN=RTCB PE=1 SV=1 5.32 3152.5 - 1.36E+06 - - - 1.2747 - 3.191 0.562 - 397.2 1 2 0 0.0021 16 0 0 0 6.51E+07 4.92E+07 - - - 7.7824 1 221125_WJC_METTL3_EV_vs_WT_F04.18787.18787.4 3.81E-13 23/102 R.TLSDYNIQK[136.11]ESTLHLVLR[166.11].L "sp|P62979|RS27A_HUMAN,sp|P0CG48|UBC_HUMAN,sp|P0CG48|UBC_HUMAN,sp|P0CG48|UBC_HUMAN,sp|P0CG48|UBC_HUMAN,sp|P0CG48|UBC_HUMAN,sp|P0CG48|UBC_HUMAN,sp|P0CG48|UBC_HUMAN,sp|P0CG48|UBC_HUMAN,sp|P0CG48|UBC_HUMAN,sp|P0CG47|UBB_HUMAN,sp|P0CG47|UBB_HUMAN,sp|P0CG47|UBB_HUMAN,sp|P62987|RL40_HUMAN,tr|F5H388|F5H388_HUMAN,tr|F5GYU3|F5GYU3_HUMAN,tr|B4DV12|B4DV12_HUMAN,tr|Q5PY61|Q5PY61_HUMAN,tr|Q5PY61|Q5PY61_HUMAN,tr|Q5PY61|Q5PY61_HUMAN,tr|F5H2Z3|F5H2Z3_HUMAN,tr|M0R2S1|M0R2S1_HUMAN,tr|J3QS39|J3QS39_HUMAN,tr|J3QTR3|J3QTR3_HUMAN,tr|Q96C32|Q96C32_HUMAN,tr|Q96C32|Q96C32_HUMAN,tr|Q96C32|Q96C32_HUMAN,tr|F5H747|F5H747_HUMAN,tr|F5H747|F5H747_HUMAN,tr|F5GXK7|F5GXK7_HUMAN,tr|F5GXK7|F5GXK7_HUMAN,tr|M0R1M6|M0R1M6_HUMAN,tr|F5H6Q2|F5H6Q2_HUMAN,tr|J3QKN0|J3QKN0_HUMAN,tr|J3QKN0|J3QKN0_HUMAN,tr|F5H265|F5H265_HUMAN,tr|A0A2R8Y422|A0A2R8Y422_HUMAN" 37 2147.1705 0.46 52245 18787 4 2147.171954 537.7999 Ubiquitin-40S ribosomal protein S27a OS=Homo sapiens OX=9606 GN=RPS27A PE=1 SV=2 6.42 3152.6 - 1.03E+06 - - - 0.6595 - 3.523 0.647 - 292.7 1 2 1 0.0014 18 0 0 0 8.24E+06 1.80E+07 - - - 5.2885 0.9917 221125_WJC_METTL3_EV_vs_WT_F04.18788.18788.3 1.57E-05 14/60 K.R[166.11]PLDDGVGNQLGALVH.Q sp|Q96I24|FUBP3_HUMAN 1 1669.8775 4.09 52246 18788 3 1669.880593 557.6331 Far upstream element-binding protein 3 OS=Homo sapiens OX=9606 GN=FUBP3 PE=1 SV=2 5.21 3152.6 - 956363 - - - 1.8295 - 2.357 0.472 - 217.4 1 1 0 0.0031 16 0 0 0 9.10E+07 2.23E+07 - - - 6.0014 1 221125_WJC_METTL3_EV_vs_WT_F04.18792.18792.3 5.30E-07 17/44 R.ADNIFPFPDR[166.11]PR[166.11].T "sp|Q17RY0|CPEB4_HUMAN,tr|H0YBG1|H0YBG1_HUMAN,tr|E5RJM0|E5RJM0_HUMAN,tr|B7ZLQ8|B7ZLQ8_HUMAN" 4 1463.7424 2.98 52250 18792 3 1463.743626 488.9214 Cytoplasmic polyadenylation element-binding protein 4 OS=Homo sapiens OX=9606 GN=CPEB4 PE=1 SV=1 6.01 3153.1 - 508757 - - - 0.8116 - 2.928 0.413 - 466.3 1 2 0 0.0012 12 0 0 0 1.28E+07 4.31E+06 - - - 6.1221 1 221125_WJC_METTL3_EV_vs_WT_F04.18797.18797.2 5.82E-08 Dec-38 K.GGINLTATC[160.03]PQSELDAETVK[136.11].S sp|Q9Y295|DRG1_HUMAN 1 2111.0296 -1 52255 18797 2 2111.033674 1056.5221 Developmentally-regulated GTP-binding protein 1 OS=Homo sapiens OX=9606 GN=DRG1 PE=1 SV=1 4.14 3153.8 - 279502 - - - 1.9303 - 3.245 0.621 - 271.6 1 2 0 0.0041 20 0 0 0 0.00E+00 0.00E+00 - - - 6.5204 1 221125_WJC_METTL3_EV_vs_WT_F04.18806.18806.3 6.05E-05 13/64 K.K[136.11]IFVGGLSVNTTVEDVK[136.11].Q "sp|O43347|MSI1H_HUMAN,tr|H0YHB7|H0YHB7_HUMAN" 2 1821.0219 1.53 52262 18806 3 1821.020547 608.0146 RNA-binding protein Musashi homolog 1 OS=Homo sapiens OX=9606 GN=MSI1 PE=1 SV=1 6.07 3154.7 - 3.19E+06 - - - -0.7238 - 2.922 0.533 - 247.5 1 2 0 -0.0013 17 0 0 0 9.88E+07 6.47E+07 - - - 7.1909 0.9999 221125_WJC_METTL3_EV_vs_WT_F04.18811.18811.3 6.48E-06 14/36 K.QNPFWWTHQR.H "sp|Q6P2Q9|PRP8_HUMAN,tr|I3L3Z8|I3L3Z8_HUMAN" 2 1398.6582 1.31 52267 18811 3 1398.661319 467.2267 Pre-mRNA-processing-splicing factor 8 OS=Homo sapiens OX=9606 GN=PRPF8 PE=1 SV=2 9.76 3155.2 - 390864 - - - 2.2643 - 2.4 0.461 - 435.6 1 2 0 0.0032 10 0 0 0 5.64E+07 4.31E+07 - - - 6.2356 0.9769 221125_WJC_METTL3_EV_vs_WT_F04.18814.18814.3 0.139 Oct-48 K.TYHPNC[160.03]FAC[160.03]TIC[160.03]K.R "sp|O14639|ABLM1_HUMAN,tr|F8W8M4|F8W8M4_HUMAN,tr|A0A494C1G0|A0A494C1G0_HUMAN,tr|A0A3B3IS55|A0A3B3IS55_HUMAN,tr|A0A0A0MRL6|A0A0A0MRL6_HUMAN,tr|A0A494C1P1|A0A494C1P1_HUMAN" 6 1670.7004 205.88 52268 18814 3 1670.699429 557.9074 Actin-binding LIM protein 1 OS=Homo sapiens OX=9606 GN=ABLIM1 PE=1 SV=3 7.67 3155.6 - 2.30E+06 - - - -0.5537 - 1.498 0.15 - 54.9 1 2 0 -0.0009 13 0 0 0 4.37E+07 2.12E+05 - - - 1.3078 1 221125_WJC_METTL3_EV_vs_WT_F04.18819.18819.3 1.60E-05 14/36 K.QNPFWWTHQR.H "sp|Q6P2Q9|PRP8_HUMAN,tr|I3L3Z8|I3L3Z8_HUMAN" 2 1398.6582 1.31 52273 18819 3 1398.656273 467.2267 Pre-mRNA-processing-splicing factor 8 OS=Homo sapiens OX=9606 GN=PRPF8 PE=1 SV=2 9.76 3156.3 - 826809 - - - -1.3434 - 2.29 0.486 - 441.4 1 2 0 -0.0019 10 0 0 0 5.64E+07 4.31E+07 - - - 6.3776 0.9997 221125_WJC_METTL3_EV_vs_WT_F04.18822.18822.2 2.92E-05 20-Oct K.VQQTVQDLFGR[166.11].A "sp|P38646|GRP75_HUMAN,tr|A0A7I2V2S7|A0A7I2V2S7_HUMAN,tr|A0A7I2V2G2|A0A7I2V2G2_HUMAN,tr|A0A7I2YQB2|A0A7I2YQB2_HUMAN,tr|D6RCD7|D6RCD7_HUMAN" 5 1299.6811 0.43 52274 18822 2 1299.678301 650.8478 "Stress-70 protein, mitochondrial OS=Homo sapiens OX=9606 GN=HSPA9 PE=1 SV=2" 5.81 3156.6 - 2.77E+06 - - - -2.1305 - 2.375 0.473 - 502.4 1 2 0 -0.0028 11 0 0 0 6.16E+07 1.43E+08 - - - 4.8737 0.8417 221125_WJC_METTL3_EV_vs_WT_F04.18825.18825.2 2.85E-05 Dec-36 K.VVGSAVGSGSITSNIVASN.S "sp|Q9Y5A9|YTHD2_HUMAN,tr|S4R3V3|S4R3V3_HUMAN" 2 1717.8846 - 52277 18825 2 1717.875746 859.9496 YTH domain-containing family protein 2 OS=Homo sapiens OX=9606 GN=YTHDF2 PE=1 SV=2 5.49 3157 - 1.35E+06 - - - -5.179 - 2.135 0.497 - 310 1 1 0 -0.0089 19 0 0 0 - - - - - 4.5738 0.997 221125_WJC_METTL3_EV_vs_WT_F04.18833.18833.4 7.38E-08 14/96 R.VIEC[160.03]DVVKDYAFVHMEK.E sp|Q96PK6|RBM14_HUMAN 1 2080.9962 1.5 52281 18833 4 2080.987696 521.2563 RNA-binding protein 14 OS=Homo sapiens OX=9606 GN=RBM14 PE=1 SV=2 4.75 3157.9 - 1.41E+07 - - - -4.0788 - 2.633 0.41 - 152.2 1 2 1 -0.0085 17 0 0 0 3.40E+08 2.26E+08 - - - 3.1284 1 221125_WJC_METTL3_EV_vs_WT_F04.18835.18835.3 1.14E-07 18/56 R.LVLEVAQHLGESTVR.T sp|P06576|ATPB_HUMAN 1 1649.9101 2.67 52283 18835 3 1649.908665 550.9773 "ATP synthase subunit beta, mitochondrial OS=Homo sapiens OX=9606 GN=ATP5F1B PE=1 SV=3" 5.4 3158.1 - 2.92E+06 - - - -0.8516 - 2.939 0.555 - 416.3 1 2 0 -0.0014 15 0 0 0 4.89E+07 1.83E+07 - - - 7.5404 0.9999 221125_WJC_METTL3_EV_vs_WT_F04.18836.18836.3 2.97E-06 15/36 K.QNPFWWTHQR[166.11].H "sp|Q6P2Q9|PRP8_HUMAN,tr|I3L3Z8|I3L3Z8_HUMAN" 2 1408.6664 1.31 52284 18836 3 1408.663337 470.5628 Pre-mRNA-processing-splicing factor 8 OS=Homo sapiens OX=9606 GN=PRPF8 PE=1 SV=2 9.76 3158.3 - 2.79E+06 - - - -2.19 - 2.348 0.495 - 507 1 2 0 -0.0031 10 0 0 0 5.64E+07 4.31E+07 - - - 6.5507 1 221125_WJC_METTL3_EV_vs_WT_F04.18838.18838.3 1.31E-12 27/64 R.VIEC[160.03]DVVK[136.11]DYAFVHMEK[136.11].E sp|Q96PK6|RBM14_HUMAN 1 2097.0246 2 52286 18838 3 2097.023278 700.0155 RNA-binding protein 14 OS=Homo sapiens OX=9606 GN=RBM14 PE=1 SV=2 4.75 3158.5 - 1.34E+06 - - - -0.6228 - 4.413 0.64 - 715 1 2 1 -0.0013 17 0 0 0 1.95E+08 9.77E+07 - - - 9.4254 1 221125_WJC_METTL3_EV_vs_WT_F04.18846.18846.3 4.59E-12 22/64 R.VIEC[160.03]DVVKDYAFVHMEK.E sp|Q96PK6|RBM14_HUMAN 1 2080.9962 2 52290 18846 3 2080.996951 694.6727 RNA-binding protein 14 OS=Homo sapiens OX=9606 GN=RBM14 PE=1 SV=2 4.75 3159.5 - 5.08E+06 - - - 0.3686 - 4.075 0.699 - 446.6 1 2 1 0.0008 17 0 0 0 1.95E+08 9.77E+07 - - - 9.8821 0.9991 221125_WJC_METTL3_EV_vs_WT_F04.18848.18848.2 1.49E-05 20-Dec K.VQQTVQDLFGR.A "sp|P38646|GRP75_HUMAN,tr|A0A7I2V2S7|A0A7I2V2S7_HUMAN,tr|A0A7I2V2G2|A0A7I2V2G2_HUMAN,tr|A0A7I2YQB2|A0A7I2YQB2_HUMAN,tr|D6RCD7|D6RCD7_HUMAN" 5 1289.6728 0.43 52292 18848 2 1289.667674 645.8437 "Stress-70 protein, mitochondrial OS=Homo sapiens OX=9606 GN=HSPA9 PE=1 SV=2" 5.81 3159.7 - 1.80E+06 - - - -3.9747 - 2.586 0.482 - 803.3 1 2 0 -0.0051 11 0 0 0 6.16E+07 1.43E+08 - - - 5.1697 0.9998 221125_WJC_METTL3_EV_vs_WT_F04.18855.18855.2 0.000212 15/26 R.SSGLPNIPVQTISR.A "sp|P02786|TFR1_HUMAN,tr|G3V0E5|G3V0E5_HUMAN" 2 1467.8045 1.27 52297 18855 2 1467.801706 734.9095 Transferrin receptor protein 1 OS=Homo sapiens OX=9606 GN=TFRC PE=1 SV=2 9.47 3160.6 - 1.63E+06 - - - -1.9321 - 2.513 0.517 - 567.6 1 2 0 -0.0028 14 0 0 0 7.90E+07 6.25E+07 - - - 5.1711 0.9999 221125_WJC_METTL3_EV_vs_WT_F04.18858.18858.3 3.87E-05 16/36 R.K[136.11]MC[160.03]LFAGFQR[166.11].K "sp|Q00839|HNRPU_HUMAN,tr|A0A1W2PQL0|A0A1W2PQL0_HUMAN,tr|A0A1W2PPL4|A0A1W2PPL4_HUMAN,tr|A0A1W2PQ74|A0A1W2PQ74_HUMAN,tr|Q5RI18|Q5RI18_HUMAN,tr|A0A1W2PP35|A0A1W2PP35_HUMAN,tr|A0A1W2PPS1|A0A1W2PPS1_HUMAN,tr|A0A1W2PRZ7|A0A1W2PRZ7_HUMAN,tr|A0A1W2PPH7|A0A1W2PPH7_HUMAN,tr|A0A1W2PQD4|A0A1W2PQD4_HUMAN,tr|A0A1W2PP34|A0A1W2PP34_HUMAN,tr|A0A1X7SBS1|A0A1X7SBS1_HUMAN" 12 1274.6383 0.73 52298 18858 3 1274.637184 425.8867 Heterogeneous nuclear ribonucleoprotein U OS=Homo sapiens OX=9606 GN=HNRNPU PE=1 SV=6 9.51 3160.9 - 2.69E+06 - - - -0.8669 - 2.083 0.437 - 298.9 1 2 0 -0.0011 10 0 0 0 7.51E+07 1.03E+08 - - - 5.5549 0.9999 221125_WJC_METTL3_EV_vs_WT_F04.18864.18864.3 1.57E-06 13/36 R.KMC[160.03]LFAGFQR.K "sp|Q00839|HNRPU_HUMAN,tr|A0A1W2PQL0|A0A1W2PQL0_HUMAN,tr|A0A1W2PPL4|A0A1W2PPL4_HUMAN,tr|A0A1W2PQ74|A0A1W2PQ74_HUMAN,tr|Q5RI18|Q5RI18_HUMAN,tr|A0A1W2PP35|A0A1W2PP35_HUMAN,tr|A0A1W2PPS1|A0A1W2PPS1_HUMAN,tr|A0A1W2PRZ7|A0A1W2PRZ7_HUMAN,tr|A0A1W2PPH7|A0A1W2PPH7_HUMAN,tr|A0A1W2PQD4|A0A1W2PQD4_HUMAN,tr|A0A1W2PP34|A0A1W2PP34_HUMAN,tr|A0A1X7SBS1|A0A1X7SBS1_HUMAN" 12 1256.6158 0.73 52302 18864 3 1256.612843 419.8792 Heterogeneous nuclear ribonucleoprotein U OS=Homo sapiens OX=9606 GN=HNRNPU PE=1 SV=6 9.51 3161.6 - 2.88E+06 - - - -2.3683 - 2.301 0.521 - 214.9 1 2 0 -0.003 10 0 0 0 7.51E+07 1.03E+08 - - - 6.7815 0.9999 221125_WJC_METTL3_EV_vs_WT_F04.18868.18868.4 1.55E-05 15/96 R.VIEC[160.03]DVVK[136.11]DYAFVHMEK[136.11].E sp|Q96PK6|RBM14_HUMAN 1 2097.0246 1.5 52304 18868 4 2097.021044 525.2634 RNA-binding protein 14 OS=Homo sapiens OX=9606 GN=RBM14 PE=1 SV=2 4.75 3162.1 - 9.65E+06 - - - -1.6881 - 2.988 0.542 - 193.8 1 2 1 -0.0035 17 0 0 0 3.40E+08 2.26E+08 - - - 4.3226 0.9862 221125_WJC_METTL3_EV_vs_WT_F04.18870.18870.2 9.46E-07 16/26 R.SSGLPNIPVQTISR[166.11].A "sp|P02786|TFR1_HUMAN,tr|G3V0E5|G3V0E5_HUMAN" 2 1477.8128 1.27 52305 18870 2 1477.798725 739.9137 Transferrin receptor protein 1 OS=Homo sapiens OX=9606 GN=TFRC PE=1 SV=2 9.47 3162.3 - 2.29E+06 - - - -9.5323 - 2.512 0.562 - 630.9 1 2 0 -0.0141 14 0 0 0 7.90E+07 6.25E+07 - - - 5.4989 0.9836 221125_WJC_METTL3_EV_vs_WT_F04.18872.18872.3 5.51E-10 20/88 H.GLGGIGMGLGPGGQPIDANHLNK.G "sp|P52272|HNRPM_HUMAN,tr|M0R019|M0R019_HUMAN,tr|M0R0N3|M0R0N3_HUMAN,tr|M0QYL3|M0QYL3_HUMAN,tr|A0A087X0X3|A0A087X0X3_HUMAN,tr|M0QZM1|M0QZM1_HUMAN" 6 2172.111 1.8 52306 18872 3 2172.12077 725.0443 Heterogeneous nuclear ribonucleoprotein M OS=Homo sapiens OX=9606 GN=HNRNPM PE=1 SV=3 6.74 3162.5 - 4.14E+06 - - - 4.5113 - 4.6 0.499 - 325.8 1 1 0 0.0098 23 0 0 0 9.97E+07 5.54E+07 - - - 7.6807 1 221125_WJC_METTL3_EV_vs_WT_F04.18877.18877.2 2.42E-11 13/36 K.YAALSVDGEDENEGEDYAE.- "sp|P23588|IF4B_HUMAN,tr|E7EX17|E7EX17_HUMAN" 2 2074.8127 - 52309 18877 2 2074.810083 1038.4136 Eukaryotic translation initiation factor 4B OS=Homo sapiens OX=9606 GN=EIF4B PE=1 SV=2 3.4 3163.2 - 1.54E+06 - - - -1.2705 - 2.959 0.735 - 377.5 1 2 0 -0.0026 19 0 0 0 - - - - - 7.136 0.9988 221125_WJC_METTL3_EV_vs_WT_F04.18880.18880.3 4.35E-05 27/88 H.GLGGIGMGLGPGGQPIDANHLNK[136.11].G "sp|P52272|HNRPM_HUMAN,tr|M0R019|M0R019_HUMAN,tr|M0R0N3|M0R0N3_HUMAN,tr|M0QYL3|M0QYL3_HUMAN,tr|A0A087X0X3|A0A087X0X3_HUMAN,tr|M0QZM1|M0QZM1_HUMAN" 6 2180.1252 1.8 52310 18880 3 2180.123936 727.7157 Heterogeneous nuclear ribonucleoprotein M OS=Homo sapiens OX=9606 GN=HNRNPM PE=1 SV=3 6.74 3163.6 - 3.25E+06 - - - -0.5665 - 4.77 0.516 - 689.3 1 1 0 -0.0012 23 0 0 0 9.97E+07 5.54E+07 - - - 7.9577 1 221125_WJC_METTL3_EV_vs_WT_F04.18881.18881.3 1.28E-07 21/60 R.GLGHQVATDALVAMEK[136.11].A sp|Q9Y3I0|RTCB_HUMAN 1 1646.8541 1.58 52311 18881 3 1646.85009 549.9587 RNA-splicing ligase RtcB homolog OS=Homo sapiens OX=9606 GN=RTCB PE=1 SV=1 5.32 3163.7 - 851718 - - - -2.4598 - 3.651 0.578 - 690.6 1 2 0 -0.0041 16 0 0 0 6.51E+07 4.13E+07 - - - 8.3058 1 221125_WJC_METTL3_EV_vs_WT_F04.18886.18886.2 7.90E-13 17/28 K.NQVAMNPTNTIFDAK[136.11].R sp|P54652|HSP72_HUMAN 1 1670.8178 0.15 52314 18886 2 1670.812495 836.4162 Heat shock-related 70 kDa protein 2 OS=Homo sapiens OX=9606 GN=HSPA2 PE=1 SV=1 5.84 3164.3 - 646140 - - - -3.1488 - 3.281 0.754 - 754 1 2 0 -0.0053 15 0 0 0 1.53E+06 1.00E+07 - - - 7.5295 0.8004 221125_WJC_METTL3_EV_vs_WT_F04.18898.18898.2 0.36 Jul-38 G.GGGGGGSVASPTSSSGSSSR.G sp|Q9Y5N1|HRH3_HUMAN 1 1637.7241 999 52322 18898 2 1637.721048 819.8693 Histamine H3 receptor OS=Homo sapiens OX=9606 GN=HRH3 PE=1 SV=2 9.75 3165.8 - 2.16E+06 - - - -1.8758 - 1.237 0.297 - 70.3 1 1 0 -0.0031 20 0 0 0 1.03E+08 0.00E+00 - - - 1.7566 1 221125_WJC_METTL3_EV_vs_WT_F04.18901.18901.2 9.33E-12 18/28 R.NPDDITQEEYGEFYK[136.11].S sp|P08238|HS90B_HUMAN 1 1854.8039 0.82 52325 18901 2 1854.798869 928.4092 Heat shock protein HSP 90-beta OS=Homo sapiens OX=9606 GN=HSP90AB1 PE=1 SV=4 3.83 3166.2 - 763964 - - - -2.734 - 3.464 0.668 - 1279.3 1 2 0 -0.0051 15 0 0 0 3.05E+07 3.70E+07 - - - 7.0278 1 221125_WJC_METTL3_EV_vs_WT_F04.18905.18905.3 1.04E-08 13/52 R.SLRPDPNFDALISK.L "sp|Q99496|RING2_HUMAN,sp|Q06587|RING1_HUMAN,tr|X6RFN3|X6RFN3_HUMAN" 3 1571.8308 1.66 52327 18905 3 1571.828816 524.9509 E3 ubiquitin-protein ligase RING2 OS=Homo sapiens OX=9606 GN=RNF2 PE=1 SV=1 5.68 3166.7 - 6.49E+06 - - - -1.2349 - 2.565 0.576 - 252.9 1 2 0 -0.0019 14 0 0 0 1.11E+08 6.71E+07 - - - 7.4646 0.9897 221125_WJC_METTL3_EV_vs_WT_F04.18910.18910.3 0.000817 15/48 K.AKLEQLFQDEVAK.A "sp|Q15149|PLEC_HUMAN,tr|H0YDN1|H0YDN1_HUMAN" 2 1517.809 32.52 52332 18910 3 1517.813727 506.9436 Plectin OS=Homo sapiens OX=9606 GN=PLEC PE=1 SV=3 4.68 3167.2 - 1.48E+06 - - - 3.1414 - 2.177 0.281 - 177.1 1 2 1 0.0048 13 0 0 0 3.05E+07 9.37E+05 - - - 3.7808 1 221125_WJC_METTL3_EV_vs_WT_F04.18912.18912.2 5.97E-07 17/28 R.NPDDITQEEYGEFYK.S sp|P08238|HS90B_HUMAN 1 1846.7897 0.82 52334 18912 2 1846.786359 924.4021 Heat shock protein HSP 90-beta OS=Homo sapiens OX=9606 GN=HSP90AB1 PE=1 SV=4 3.83 3167.4 - 1.14E+06 - - - -1.8307 - 3.59 0.707 - 1339 1 2 0 -0.0034 15 0 0 0 3.05E+07 3.70E+07 - - - 7.4042 1 221125_WJC_METTL3_EV_vs_WT_F04.18913.18913.2 8.90E-09 16/32 R.GSNNVALGYDEGSIIVK[136.11].L "sp|P35606|COPB2_HUMAN,tr|H0Y938|H0Y938_HUMAN,tr|A0A7I2V258|A0A7I2V258_HUMAN,tr|H0YAC7|H0YAC7_HUMAN" 4 1742.893 0.6 52335 18913 2 1742.888378 872.4538 Coatomer subunit beta' OS=Homo sapiens OX=9606 GN=COPB2 PE=1 SV=2 4.37 3167.5 - 737648 - - - -2.6686 - 3.091 0.585 - 848.4 1 2 0 -0.0047 17 0 0 0 3.71E+06 6.18E+06 - - - 6.1348 0.9998 221125_WJC_METTL3_EV_vs_WT_F04.18915.18915.3 5.77E-06 Dec-56 K.DVDNAYMIKVELQSK.V sp|P35908|K22E_HUMAN 1 1751.8764 999 52337 18915 3 1751.875974 584.9661 "Keratin, type II cytoskeletal 2 epidermal OS=Homo sapiens OX=9606 GN=KRT2 PE=1 SV=2" 4.56 3167.8 - 405497 - - - -0.2352 - 2.188 0.471 - 111.4 1 2 1 -0.0004 15 0 0 0 2.68E+06 0.00E+00 - - - 5.8342 1 221125_WJC_METTL3_EV_vs_WT_F04.18918.18918.2 6.54E-07 13/24 K.EQLDNQLDAYMSK.T "sp|Q9Y3Y2|CHTOP_HUMAN,tr|X6R700|X6R700_HUMAN" 2 1553.7032 6.22 52338 18918 2 1553.700718 777.8589 Chromatin target of PRMT1 protein OS=Homo sapiens OX=9606 GN=CHTOP PE=1 SV=2 4.03 3168.2 - 6.75E+06 - - - -1.5801 - 2.846 0.633 - 676.8 1 2 0 -0.0025 13 0 0 0 2.83E+08 4.55E+07 - - - 6.3999 1 221125_WJC_METTL3_EV_vs_WT_F04.18919.18919.3 5.96E-08 19/56 K.QC[160.03]ANLQAAIADAEQR.G "sp|P04259|K2C6B_HUMAN,sp|P02538|K2C6A_HUMAN" 2 1657.7842 0.98 52339 18919 3 1657.782685 553.602 "Keratin, type II cytoskeletal 6B OS=Homo sapiens OX=9606 GN=KRT6B PE=1 SV=5" 4.37 3168.3 - 1.55E+06 - - - -0.9247 - 3.451 0.604 - 710.4 1 2 0 -0.0015 15 0 0 0 2.33E+07 2.38E+07 - - - 8.5057 0.9999 221125_WJC_METTL3_EV_vs_WT_F04.18924.18924.3 0.000174 14/52 K.IAILTC[160.03]PFEPPKPK.T "sp|P48643|TCPE_HUMAN,tr|E9PCA1|E9PCA1_HUMAN,tr|B7ZAR1|B7ZAR1_HUMAN,tr|E7ENZ3|E7ENZ3_HUMAN" 4 1609.8902 1.65 52344 18924 3 1609.887713 537.6373 T-complex protein 1 subunit epsilon OS=Homo sapiens OX=9606 GN=CCT5 PE=1 SV=1 8.2 3169 - 762675 - - - -1.5361 - 2.623 0.434 - 276.4 1 2 0 -0.0025 14 0 0 0 1.10E+07 6.65E+06 - - - 5.9407 0.9994 221125_WJC_METTL3_EV_vs_WT_F04.18926.18926.2 0.00443 26-Oct K.THLPGFVEQAEALK[136.11].A sp|P30044|PRDX5_HUMAN 1 1546.8235 1.57 52346 18926 2 1546.825263 774.419 "Peroxiredoxin-5, mitochondrial OS=Homo sapiens OX=9606 GN=PRDX5 PE=1 SV=4" 5.37 3169.2 - 751862 - - - 1.1443 - 1.756 0.377 - 171.6 1 2 0 0.0018 14 0 0 0 3.07E+07 1.96E+07 - - - 3.2379 0.9999 221125_WJC_METTL3_EV_vs_WT_F04.18927.18927.2 0.00534 16/26 R.SLRPDPNFDALISK.L "sp|Q99496|RING2_HUMAN,sp|Q06587|RING1_HUMAN,tr|X6RFN3|X6RFN3_HUMAN" 3 1571.8308 3.62 52347 18927 2 1571.832241 786.9227 E3 ubiquitin-protein ligase RING2 OS=Homo sapiens OX=9606 GN=RNF2 PE=1 SV=1 5.68 3169.4 - 704233 - - - 0.9441 - 2.983 0.493 - 924.2 1 2 0 0.0015 14 0 0 0 8.48E+06 2.34E+06 - - - 5.4245 0.9975 221125_WJC_METTL3_EV_vs_WT_F04.18928.18928.3 1.64E-07 22/68 Q.LAGTSLQAAAQSLNVQSK.S "sp|P14859|PO2F1_HUMAN,tr|A0A0A0MT46|A0A0A0MT46_HUMAN" 2 1785.9585 0.89 52348 18928 3 1785.954497 596.3268 "POU domain, class 2, transcription factor 1 OS=Homo sapiens OX=9606 GN=POU2F1 PE=1 SV=2" 8.75 3169.5 - 695813 - - - -2.2285 - 4.21 0.529 - 909 1 1 0 -0.004 18 0 0 0 1.09E+07 1.23E+07 - - - 8.0162 1 221125_WJC_METTL3_EV_vs_WT_F04.18929.18929.3 0.000479 18/48 R.NILSVVGTDALKK.T sp|O43172|PRP4_HUMAN 1 1356.7977 2.9 52349 18929 3 1356.796762 453.2732 U4\U6 small nuclear ribonucleoprotein Prp4 OS=Homo sapiens OX=9606 GN=PRPF4 PE=1 SV=2 8.59 3169.6 - 536610 - - - -0.6663 - 3.447 0.392 - 324.5 1 2 0 -0.0009 13 0 0 0 1.66E+07 5.73E+06 - - - 6.2654 0.9998 221125_WJC_METTL3_EV_vs_WT_F04.18932.18932.3 1.52E-05 Oct-36 K.DYAFVHFEDR[166.11].G "sp|O43390|HNRPR_HUMAN,tr|B4DT28|B4DT28_HUMAN,tr|A0A6Q8PH31|A0A6Q8PH31_HUMAN,tr|A0A6Q8PH35|A0A6Q8PH35_HUMAN,tr|A0A286YEZ8|A0A286YEZ8_HUMAN" 5 1307.581 1.42 52352 18932 3 1307.581565 436.8676 Heterogeneous nuclear ribonucleoprotein R OS=Homo sapiens OX=9606 GN=HNRNPR PE=1 SV=1 4.54 3170 - 299970 - - - 0.416 - 2.143 0.345 - 169.8 1 2 0 0.0005 10 0 0 0 2.98E+06 2.10E+06 - - - 4.6122 0.9999 221125_WJC_METTL3_EV_vs_WT_F04.18933.18933.3 2.78E-06 Nov-44 K.KYSSLNLFDTYK.G sp|P48634|PRC2A_HUMAN 1 1477.7453 1.56 52353 18933 3 1477.748182 493.589 Protein PRRC2A OS=Homo sapiens OX=9606 GN=PRRC2A PE=1 SV=3 8.43 3170.1 - 273859 - - - 1.953 - 2.411 0.508 - 211.8 1 2 0 0.0029 12 0 0 0 4.02E+06 2.58E+06 - - - 6.6422 1 221125_WJC_METTL3_EV_vs_WT_F04.18936.18936.3 0.00226 Nov-52 K.THLPGFVEQAEALK.A sp|P30044|PRDX5_HUMAN 1 1538.8093 1.49 52354 18936 3 1538.809396 513.9437 "Peroxiredoxin-5, mitochondrial OS=Homo sapiens OX=9606 GN=PRDX5 PE=1 SV=4" 5.37 3170.6 - 8.81E+06 - - - 0.0669 - 2.478 0.465 - 206 1 2 0 0.0001 14 0 0 0 2.56E+08 1.72E+08 - - - 6.1358 1 221125_WJC_METTL3_EV_vs_WT_F04.18937.18937.3 1.54E-10 15/52 R.SLR[166.11]PDPNFDALISK[136.11].L "sp|Q99496|RING2_HUMAN,sp|Q06587|RING1_HUMAN,tr|X6RFN3|X6RFN3_HUMAN" 3 1589.8532 1.66 52355 18937 3 1589.852391 530.9584 E3 ubiquitin-protein ligase RING2 OS=Homo sapiens OX=9606 GN=RNF2 PE=1 SV=1 5.68 3170.6 - 5.67E+06 - - - -0.5258 - 2.629 0.608 - 361.8 1 2 0 -0.0008 14 0 0 0 1.11E+08 6.71E+07 - - - 7.8871 1 221125_WJC_METTL3_EV_vs_WT_F04.18941.18941.3 1.39E-05 19/64 R.ATISNPITGDLETVHYR[166.11].L sp|P13674|P4HA1_HUMAN 1 1895.9617 1.25 52359 18941 3 1895.961277 632.9945 Prolyl 4-hydroxylase subunit alpha-1 OS=Homo sapiens OX=9606 GN=P4HA1 PE=1 SV=2 5.32 3170.9 - 1.74E+06 - - - -0.2025 - 3.209 0.548 - 430.2 1 2 0 -0.0004 17 0 0 0 1.47E+07 1.18E+07 - - - 7.5951 1 221125_WJC_METTL3_EV_vs_WT_F04.18942.18942.3 1.38E-06 18/68 R.ILAGLGFDPEMQNR[166.11]PTQK[136.11].F "sp|Q8NE71|ABCF1_HUMAN,tr|Q5STZ8|Q5STZ8_HUMAN,tr|H0YGW7|H0YGW7_HUMAN" 3 2032.0531 1.23 52360 18942 3 2032.055912 678.3583 ATP-binding cassette sub-family F member 1 OS=Homo sapiens OX=9606 GN=ABCF1 PE=1 SV=2 6.07 3171 - 1.61E+06 - - - 1.4006 - 2.947 0.46 - 285.7 1 2 0 0.0028 18 0 0 0 1.25E+07 1.02E+07 - - - 6.359 0.9999 221125_WJC_METTL3_EV_vs_WT_F04.18944.18944.3 8.51E-06 Nov-48 R.RIGFDVVTLSGTR.G "sp|Q9BSD7|NTPCR_HUMAN,tr|Q5TDF0|Q5TDF0_HUMAN" 2 1419.7834 1.07 52362 18944 3 1419.783675 474.2684 Cancer-related nucleoside-triphosphatase OS=Homo sapiens OX=9606 GN=NTPCR PE=1 SV=1 9.6 3171.1 - 1.31E+06 - - - 0.1845 - 2.269 0.442 - 144 1 2 0 0.0003 13 0 0 0 1.16E+07 1.09E+07 - - - 5.6893 1 221125_WJC_METTL3_EV_vs_WT_F04.18948.18948.2 8.10E-15 17/32 R.AADTDGDGQVNYEEFVR.V sp|P27482|CALL3_HUMAN 1 1884.8126 999 52366 18948 2 1884.812864 943.4136 Calmodulin-like protein 3 OS=Homo sapiens OX=9606 GN=CALML3 PE=1 SV=2 3.77 3171.6 - 1.11E+06 - - - 0.1401 - 3.838 0.808 - 1023.3 1 2 0 0.0003 17 0 0 0 1.10E+07 0.00E+00 - - - 8.3154 1 221125_WJC_METTL3_EV_vs_WT_F04.18950.18950.3 6.31E-08 Dec-56 R.NPDDITQEEYGEFYK[136.11].S sp|P08238|HS90B_HUMAN 1 1854.8039 0.84 52368 18950 3 1854.804548 619.2753 Heat shock protein HSP 90-beta OS=Homo sapiens OX=9606 GN=HSP90AB1 PE=1 SV=4 3.83 3171.8 - 840387 - - - 0.3278 - 2.357 0.564 - 193.8 1 2 0 0.0006 15 0 0 0 4.40E+06 5.24E+06 - - - 7.0651 1 221125_WJC_METTL3_EV_vs_WT_F04.18951.18951.3 3.70E-06 13/60 K.SLVTVETDAHGSFC[160.03]FK.A "sp|Q15155|NOMO1_HUMAN,sp|Q5JPE7|NOMO2_HUMAN,sp|P69849|NOMO3_HUMAN,tr|A0A7I2V3P4|A0A7I2V3P4_HUMAN,tr|A0A7I2V6B0|A0A7I2V6B0_HUMAN,tr|A0A7I2V4D7|A0A7I2V4D7_HUMAN,tr|A0A7I2V4T6|A0A7I2V4T6_HUMAN,tr|A0A0G2JP90|A0A0G2JP90_HUMAN,tr|A0A087X117|A0A087X117_HUMAN,tr|A0A0G2JN29|A0A0G2JN29_HUMAN,tr|A0A7I2V2Z5|A0A7I2V2Z5_HUMAN,tr|H3BPS9|H3BPS9_HUMAN,tr|A0A087WW46|A0A087WW46_HUMAN,tr|J3KN36|J3KN36_HUMAN" 14 1796.8403 0.31 52369 18951 3 1796.839173 599.9541 Nodal modulator 1 OS=Homo sapiens OX=9606 GN=NOMO1 PE=1 SV=5 5.3 3171.9 - 1.71E+06 - - - -0.6472 - 2.619 0.476 - 133.8 1 2 0 -0.0012 16 0 0 0 3.31E+06 1.08E+07 - - - 6.317 0.9998 221125_WJC_METTL3_EV_vs_WT_F04.18952.18952.3 0.00218 13/48 R.NILSVVGTDALK[136.11]K[136.11].T sp|O43172|PRP4_HUMAN 1 1372.8261 2.9 52370 18952 3 1372.825458 458.616 U4\U6 small nuclear ribonucleoprotein Prp4 OS=Homo sapiens OX=9606 GN=PRPF4 PE=1 SV=2 8.59 3172 - 699748 - - - -0.4429 - 2.693 0.316 - 133.8 1 2 0 -0.0006 13 0 0 0 1.66E+07 5.73E+06 - - - 4.7489 1 221125_WJC_METTL3_EV_vs_WT_F04.18955.18955.2 3.72E-10 13/32 R.GSNNVALGYDEGSIIVK.L "sp|P35606|COPB2_HUMAN,tr|H0Y938|H0Y938_HUMAN,tr|A0A7I2V258|A0A7I2V258_HUMAN,tr|H0YAC7|H0YAC7_HUMAN" 4 1734.8788 0.6 52373 18955 2 1734.879685 868.4467 Coatomer subunit beta' OS=Homo sapiens OX=9606 GN=COPB2 PE=1 SV=2 4.37 3172.4 - 587032 - - - 0.4934 - 2.703 0.621 - 451.1 1 2 0 0.0009 17 0 0 0 3.71E+06 6.18E+06 - - - 6.0721 0.9999 221125_WJC_METTL3_EV_vs_WT_F04.18958.18958.3 7.90E-05 13/44 K.K[136.11]IDGLLIDQIQR[166.11].D "sp|P82650|RT22_HUMAN,tr|G5E9W7|G5E9W7_HUMAN,tr|A0A7P0MKV3|A0A7P0MKV3_HUMAN,tr|H7C5L9|H7C5L9_HUMAN" 4 1428.8419 1.07 52375 18958 3 1428.841636 477.2879 "28S ribosomal protein S22, mitochondrial OS=Homo sapiens OX=9606 GN=MRPS22 PE=1 SV=1" 5.96 3172.7 - 818214 - - - -0.2086 - 2.34 0.383 - 372.5 1 2 0 -0.0003 12 0 0 0 3.59E+06 3.37E+06 - - - 5.1665 1 221125_WJC_METTL3_EV_vs_WT_F04.18959.18959.3 1.77E-12 22/80 R.ATGEADVEFVTHEDAVAAMSK.D sp|P31942|HNRH3_HUMAN 1 2176.9947 4.81 52376 18959 3 2176.993736 726.6722 Heterogeneous nuclear ribonucleoprotein H3 OS=Homo sapiens OX=9606 GN=HNRNPH3 PE=1 SV=2 4.17 3172.8 - 2.31E+06 - - - -0.4263 - 4.962 0.705 - 860.2 1 2 0 -0.0009 21 0 0 0 1.34E+07 2.78E+06 - - - 10.2401 1 221125_WJC_METTL3_EV_vs_WT_F04.18961.18961.3 5.02E-07 14/52 R.LLHEVQELTTEVEK.L "sp|Q13561|DCTN2_HUMAN,tr|H0YHL1|H0YHL1_HUMAN,tr|A8K8J9|A8K8J9_HUMAN,tr|F8W1I6|F8W1I6_HUMAN,tr|A0A7I2V4H4|A0A7I2V4H4_HUMAN,tr|A0A7I2V390|A0A7I2V390_HUMAN,tr|A0A7I2V4Y9|A0A7I2V4Y9_HUMAN,tr|F8VRV7|F8VRV7_HUMAN,tr|F8VW18|F8VW18_HUMAN" 9 1666.8778 3.37 52378 18961 3 1666.878321 556.6332 Dynactin subunit 2 OS=Homo sapiens OX=9606 GN=DCTN2 PE=1 SV=4 4.48 3172.9 - 2.20E+06 - - - 0.3324 - 2.993 0.499 - 425.9 1 2 0 0.0006 14 0 0 0 1.37E+08 4.08E+07 - - - 7.0166 0.9994 221125_WJC_METTL3_EV_vs_WT_F04.18963.18963.3 0.0932 Dec-48 R.R[166.11]IGFDVVTLSGTR[166.11].G "sp|Q9BSD7|NTPCR_HUMAN,tr|Q5TDF0|Q5TDF0_HUMAN" 2 1439.8 6.57 52380 18963 3 1439.799472 480.9406 Cancer-related nucleoside-triphosphatase OS=Homo sapiens OX=9606 GN=NTPCR PE=1 SV=1 9.6 3173.1 - 1.48E+06 - - - -0.3341 - 2.219 0.265 - 203.3 1 2 0 -0.0005 13 0 0 0 7.65E+07 1.17E+07 - - - 3.6554 1 221125_WJC_METTL3_EV_vs_WT_F04.18965.18965.2 3.06E-12 21/34 Q.LAGTSLQAAAQSLNVQSK.S "sp|P14859|PO2F1_HUMAN,tr|A0A0A0MT46|A0A0A0MT46_HUMAN" 2 1785.9585 999 52382 18965 2 1785.958464 893.9865 "POU domain, class 2, transcription factor 1 OS=Homo sapiens OX=9606 GN=POU2F1 PE=1 SV=2" 8.75 3173.3 - 897147 - - - -0.0073 - 4.226 0.62 - 1725 1 1 0 0 18 0 0 0 5.26E+06 0.00E+00 - - - 7.1637 1 221125_WJC_METTL3_EV_vs_WT_F04.18967.18967.3 7.06E-09 15/52 R.SHPLDPIDTVDFER[166.11].E "sp|P47897|SYQ_HUMAN,tr|A0A0U1RQL2|A0A0U1RQL2_HUMAN,tr|A0A0U1RRI9|A0A0U1RRI9_HUMAN,tr|C9J165|C9J165_HUMAN,tr|A0A0U1RQT0|A0A0U1RQT0_HUMAN,tr|A0A1B0GVU9|A0A1B0GVU9_HUMAN,tr|A0A0U1RQE9|A0A0U1RQE9_HUMAN,tr|A0A0U1RQM8|A0A0U1RQM8_HUMAN,tr|A0A0U1RQU2|A0A0U1RQU2_HUMAN" 9 1649.7925 1.18 52384 18967 3 1649.795815 550.9381 Glutamine--tRNA ligase OS=Homo sapiens OX=9606 GN=QARS1 PE=1 SV=1 4.22 3173.5 - 802697 - - - 2.0269 - 2.624 0.531 - 415.9 1 2 0 0.0033 14 0 0 0 3.73E+07 3.15E+07 - - - 7.0229 1 221125_WJC_METTL3_EV_vs_WT_F04.18968.18968.3 0.00118 Nov-36 K.DYAFVHFEDR.G "sp|O43390|HNRPR_HUMAN,tr|B4DT28|B4DT28_HUMAN,tr|A0A6Q8PH31|A0A6Q8PH31_HUMAN,tr|A0A6Q8PH35|A0A6Q8PH35_HUMAN,tr|A0A286YEZ8|A0A286YEZ8_HUMAN" 5 1297.5728 1.42 52385 18968 3 1297.572668 433.5315 Heterogeneous nuclear ribonucleoprotein R OS=Homo sapiens OX=9606 GN=HNRNPR PE=1 SV=1 4.54 3173.6 - 707858 - - - -0.064 - 2.097 0.552 - 227.7 1 2 0 -0.0001 10 0 0 0 2.98E+06 2.10E+06 - - - 6.8568 0.9999 221125_WJC_METTL3_EV_vs_WT_F04.18970.18970.3 0.000135 13/44 K.KIDGLLIDQIQR.D "sp|P82650|RT22_HUMAN,tr|G5E9W7|G5E9W7_HUMAN,tr|A0A7P0MKV3|A0A7P0MKV3_HUMAN,tr|H7C5L9|H7C5L9_HUMAN" 4 1410.8195 1.07 52387 18970 3 1410.820801 471.2804 "28S ribosomal protein S22, mitochondrial OS=Homo sapiens OX=9606 GN=MRPS22 PE=1 SV=1" 5.96 3173.9 - 676262 - - - 0.9477 - 2.391 0.414 - 329 1 2 0 0.0013 12 0 0 0 3.59E+06 3.37E+06 - - - 5.5716 1 221125_WJC_METTL3_EV_vs_WT_F04.18971.18971.2 2.09E-10 15/28 R.NFILDQC[160.03]NVYNSGQR.R "sp|Q1KMD3|HNRL2_HUMAN,tr|H3BQZ7|H3BQZ7_HUMAN" 2 1826.837 1.26 52388 18971 2 1826.837564 914.4258 Heterogeneous nuclear ribonucleoprotein U-like protein 2 OS=Homo sapiens OX=9606 GN=HNRNPUL2 PE=1 SV=1 5.83 3174 - 639314 - - - 0.3191 - 2.956 0.674 - 864.6 1 2 0 0.0006 15 0 0 0 5.23E+06 4.17E+06 - - - 6.6836 0.9924 221125_WJC_METTL3_EV_vs_WT_F04.18972.18972.3 3.39E-05 Nov-44 V.KLALDVEIATYR.K "sp|P48668|K2C6C_HUMAN,sp|Q01546|K22O_HUMAN,sp|P12035|K2C3_HUMAN,sp|P04259|K2C6B_HUMAN,sp|P13647|K2C5_HUMAN,sp|P35908|K22E_HUMAN,sp|O95678|K2C75_HUMAN,sp|Q5XKE5|K2C79_HUMAN,sp|P02538|K2C6A_HUMAN,tr|H0YI76|H0YI76_HUMAN,tr|H0YID6|H0YID6_HUMAN" 11 1390.782 0.93 52389 18972 3 1390.78256 464.6013 "Keratin, type II cytoskeletal 6C OS=Homo sapiens OX=9606 GN=KRT6C PE=1 SV=3" 6.07 3174.2 - 555369 - - - 0.3911 - 2.31 0.417 - 231.5 1 1 0 0.0005 12 0 0 0 4.56E+06 4.88E+06 - - - 5.5097 0.9999 221125_WJC_METTL3_EV_vs_WT_F04.18974.18974.2 7.57E-07 Dec-36 R.ALSSGGSITSPPLSPALPK.Y "sp|Q6Y7W6|GGYF2_HUMAN,tr|F8WCD5|F8WCD5_HUMAN,tr|C9JPV7|C9JPV7_HUMAN,tr|C9JRZ2|C9JRZ2_HUMAN,tr|C9J0V6|C9J0V6_HUMAN,tr|I1E4Y6|I1E4Y6_HUMAN,tr|C9JHT0|C9JHT0_HUMAN,tr|C9JXQ0|C9JXQ0_HUMAN,tr|C9JHW1|C9JHW1_HUMAN,tr|C9JW88|C9JW88_HUMAN,tr|E7ESB6|E7ESB6_HUMAN" 11 1778.9778 999 52391 18974 2 1778.976863 890.4962 GRB10-interacting GYF protein 2 OS=Homo sapiens OX=9606 GN=GIGYF2 PE=1 SV=1 8.8 3174.4 - 429211 - - - -0.5351 - 2.481 0.568 - 205.4 1 2 0 -0.001 19 0 0 0 4.04E+06 0.00E+00 - - - 5.4699 1 221125_WJC_METTL3_EV_vs_WT_F04.18978.18978.2 1.39E-08 14/28 K.QC[160.03]ANLQAAIADAEQR.G "sp|P04259|K2C6B_HUMAN,sp|P02538|K2C6A_HUMAN" 2 1657.7842 999 52394 18978 2 1657.78185 829.8994 "Keratin, type II cytoskeletal 6B OS=Homo sapiens OX=9606 GN=KRT6B PE=1 SV=5" 4.37 3174.9 - 2.23E+06 - - - -1.4284 - 3.074 0.668 - 638.5 1 2 0 -0.0024 15 0 0 0 1.29E+07 0.00E+00 - - - 6.735 0.9998 221125_WJC_METTL3_EV_vs_WT_F04.18980.18980.3 0.0103 Nov-56 K.GGQTHLGLPVFNTVK.E "sp|P53597|SUCA_HUMAN,tr|A0A494C0D1|A0A494C0D1_HUMAN" 2 1566.8518 1.57 52396 18980 3 1566.850526 523.2912 "Succinate--CoA ligase [ADP\GDP-forming] subunit alpha, mitochondrial OS=Homo sapiens OX=9606 GN=SUCLG1 PE=1 SV=4" 8.76 3175 - 6.44E+06 - - - -0.8303 - 2.154 0.356 - 128.3 1 2 0 -0.0013 15 0 0 0 1.13E+08 7.20E+07 - - - 4.5109 0.9999 221125_WJC_METTL3_EV_vs_WT_F04.18981.18981.3 2.68E-07 17/52 R.YQVELENLKDEYVR.T "sp|P82094|TMF1_HUMAN,tr|A0A2R8Y7M0|A0A2R8Y7M0_HUMAN" 2 1796.8945 2.14 52397 18981 3 1796.896261 599.9721 TATA element modulatory factor OS=Homo sapiens OX=9606 GN=TMF1 PE=1 SV=2 4.41 3175 - 4.43E+06 - - - 0.9917 - 3.164 0.585 - 271.7 1 2 1 0.0018 14 0 0 0 1.15E+08 5.36E+07 - - - 8.1227 1 221125_WJC_METTL3_EV_vs_WT_F04.18983.18983.3 4.05E-07 16/52 R.LLHEVQELTTEVEK[136.11].L "sp|Q13561|DCTN2_HUMAN,tr|H0YHL1|H0YHL1_HUMAN,tr|A8K8J9|A8K8J9_HUMAN,tr|F8W1I6|F8W1I6_HUMAN,tr|A0A7I2V4H4|A0A7I2V4H4_HUMAN,tr|A0A7I2V390|A0A7I2V390_HUMAN,tr|A0A7I2V4Y9|A0A7I2V4Y9_HUMAN,tr|F8VRV7|F8VRV7_HUMAN,tr|F8VW18|F8VW18_HUMAN" 9 1674.892 3.37 52399 18983 3 1674.89049 559.3046 Dynactin subunit 2 OS=Homo sapiens OX=9606 GN=DCTN2 PE=1 SV=4 4.48 3175.1 - 2.57E+06 - - - -0.8818 - 3.113 0.516 - 505.1 1 2 0 -0.0015 14 0 0 0 1.37E+08 4.08E+07 - - - 7.3103 0.9993 221125_WJC_METTL3_EV_vs_WT_F04.18985.18985.3 0.00449 15/80 K.EEPPKELPAAEPVLSPLEGTK.M "sp|Q9BY77|PDIP3_HUMAN,tr|F6VRR5|F6VRR5_HUMAN" 2 2230.1733 2.57 52401 18985 3 2230.170437 744.3984 Polymerase delta-interacting protein 3 OS=Homo sapiens OX=9606 GN=POLDIP3 PE=1 SV=2 4.33 3175.3 - 1.95E+06 - - - -1.2748 - 2.464 0.378 - 207.2 1 2 1 -0.0028 21 0 0 0 4.06E+07 1.58E+07 - - - 4.9155 1 221125_WJC_METTL3_EV_vs_WT_F04.18986.18986.2 5.16E-10 14/32 R.GSTAPVGGGAFPTIVER.E sp|Q15084|PDIA6_HUMAN 1 1614.8366 1.75 52402 18986 2 1614.834732 808.4256 Protein disulfide-isomerase A6 OS=Homo sapiens OX=9606 GN=PDIA6 PE=1 SV=1 6 3175.5 - 960225 - - - -1.1382 - 2.574 0.655 - 459.4 1 2 0 -0.0018 17 0 0 0 2.02E+07 1.15E+07 - - - 6.2027 0.9997 221125_WJC_METTL3_EV_vs_WT_F04.18987.18987.2 0.00014 22-Dec K.NYIQGINLVQAK.K "sp|P52815|RM12_HUMAN,tr|B4DLN1|B4DLN1_HUMAN" 2 1359.7511 2.92 52403 18987 2 1359.751942 680.8828 "39S ribosomal protein L12, mitochondrial OS=Homo sapiens OX=9606 GN=MRPL12 PE=1 SV=2" 8.59 3175.6 - 888392 - - - 0.656 - 1.948 0.389 - 187.2 1 2 0 0.0009 12 0 0 0 4.18E+07 1.43E+07 - - - 3.6683 1 221125_WJC_METTL3_EV_vs_WT_F04.18991.18991.2 2.65E-06 16/28 R.NFILDQC[160.03]NVYNSGQR[166.11].R "sp|Q1KMD3|HNRL2_HUMAN,tr|H3BQZ7|H3BQZ7_HUMAN" 2 1836.8453 1.26 52407 18991 2 1836.840957 919.4299 Heterogeneous nuclear ribonucleoprotein U-like protein 2 OS=Homo sapiens OX=9606 GN=HNRNPUL2 PE=1 SV=1 5.83 3176.1 - 814744 - - - -2.3377 - 2.967 0.637 - 895.8 1 2 0 -0.0043 15 0 0 0 5.23E+06 4.17E+06 - - - 6.4183 0.9998 221125_WJC_METTL3_EV_vs_WT_F04.18994.18994.2 7.05E-06 13/26 R.LLHEVQELTTEVEK[136.11].L "sp|Q13561|DCTN2_HUMAN,tr|H0YHL1|H0YHL1_HUMAN,tr|A8K8J9|A8K8J9_HUMAN,tr|F8W1I6|F8W1I6_HUMAN,tr|A0A7I2V4H4|A0A7I2V4H4_HUMAN,tr|A0A7I2V390|A0A7I2V390_HUMAN,tr|A0A7I2V4Y9|A0A7I2V4Y9_HUMAN,tr|F8VRV7|F8VRV7_HUMAN,tr|F8VW18|F8VW18_HUMAN" 9 1674.892 4.11 52410 18994 2 1674.892997 838.4533 Dynactin subunit 2 OS=Homo sapiens OX=9606 GN=DCTN2 PE=1 SV=4 4.48 3176.5 - 602883 - - - 0.615 - 2.512 0.409 - 473.2 1 2 0 0.001 14 0 0 0 5.13E+07 1.25E+07 - - - 4.373 1 221125_WJC_METTL3_EV_vs_WT_F04.18995.18995.3 0.00234 16/48 K.MFVGGLSWDTSKK.D "sp|Q99729|ROAA_HUMAN,tr|D6R9P3|D6R9P3_HUMAN,tr|D6RD18|D6RD18_HUMAN,tr|D6RBZ0|D6RBZ0_HUMAN" 4 1454.7228 1.43 52411 18995 3 1454.723772 485.9149 Heterogeneous nuclear ribonucleoprotein A\B OS=Homo sapiens OX=9606 GN=HNRNPAB PE=1 SV=2 8.35 3176.6 - 564435 - - - 0.6778 - 2.84 0.474 - 364.7 1 2 0 0.001 13 0 0 0 1.92E+07 1.34E+07 - - - 6.6544 0.999 221125_WJC_METTL3_EV_vs_WT_F04.18996.18996.3 8.59E-05 Oct-52 K.NQQPVLPAGLQVPK[136.11].T sp|Q01780|EXOSX_HUMAN 1 1495.8602 1 52412 18996 3 1495.854791 499.6273 Exosome component 10 OS=Homo sapiens OX=9606 GN=EXOSC10 PE=1 SV=2 8.75 3176.8 - 541144 - - - -3.6247 - 2.21 0.361 - 107.7 1 2 0 -0.0054 14 0 0 0 3.96E+06 3.95E+06 - - - 4.6707 1 221125_WJC_METTL3_EV_vs_WT_F04.18997.18997.2 3.87E-11 14/28 K.SDAYYC[160.03]TGDVTAWTK.C "sp|P09874|PARP1_HUMAN,tr|A0A7I2V625|A0A7I2V625_HUMAN,tr|A0A7I2V3E1|A0A7I2V3E1_HUMAN" 3 1736.7352 0.85 52413 18997 2 1736.73441 869.3749 Poly [ADP-ribose] polymerase 1 OS=Homo sapiens OX=9606 GN=PARP1 PE=1 SV=4 4.21 3176.9 - 527927 - - - -0.456 - 3.017 0.781 - 593 1 2 0 -0.0008 15 0 0 0 8.08E+07 9.46E+07 - - - 7.5241 1 221125_WJC_METTL3_EV_vs_WT_F04.18999.18999.2 7.67E-11 20/26 R.LLHEVQELTTEVEK.L "sp|Q13561|DCTN2_HUMAN,tr|H0YHL1|H0YHL1_HUMAN,tr|A8K8J9|A8K8J9_HUMAN,tr|F8W1I6|F8W1I6_HUMAN,tr|A0A7I2V4H4|A0A7I2V4H4_HUMAN,tr|A0A7I2V390|A0A7I2V390_HUMAN,tr|A0A7I2V4Y9|A0A7I2V4Y9_HUMAN,tr|F8VRV7|F8VRV7_HUMAN,tr|F8VW18|F8VW18_HUMAN" 9 1666.8778 4.09 52414 18999 2 1666.875091 834.4462 Dynactin subunit 2 OS=Homo sapiens OX=9606 GN=DCTN2 PE=1 SV=4 4.48 3177.1 - 3.90E+06 - - - -1.6054 - 3.533 0.672 - 1717 1 2 0 -0.0027 14 0 0 0 5.10E+07 1.25E+07 - - - 7.1708 0.9166 221125_WJC_METTL3_EV_vs_WT_F04.19002.19002.3 0.00159 Oct-40 K.EIK[136.11]DILIQYDR[166.11].T "sp|P62249|RS16_HUMAN,tr|M0R210|M0R210_HUMAN" 2 1422.7838 0.84 52417 19002 3 1422.782507 475.2685 40S ribosomal protein S16 OS=Homo sapiens OX=9606 GN=RPS16 PE=1 SV=2 4.56 3177.4 - 3.43E+06 - - - -0.8736 - 1.63 0.133 - 191.3 1 2 1 -0.0012 11 0 0 0 1.23E+08 1.46E+08 - - - 1.4104 1 221125_WJC_METTL3_EV_vs_WT_F04.19003.19003.2 6.76E-12 16/28 K.SDAYYC[160.03]TGDVTAWTK[136.11].C "sp|P09874|PARP1_HUMAN,tr|A0A7I2V625|A0A7I2V625_HUMAN,tr|A0A7I2V3E1|A0A7I2V3E1_HUMAN" 3 1744.7494 0.85 52418 19003 2 1744.744831 873.382 Poly [ADP-ribose] polymerase 1 OS=Homo sapiens OX=9606 GN=PARP1 PE=1 SV=4 4.21 3177.5 - 2.73E+06 - - - -2.6199 - 3.193 0.795 - 844.9 1 2 0 -0.0046 15 0 0 0 8.08E+07 9.46E+07 - - - 7.7657 0.9995 221125_WJC_METTL3_EV_vs_WT_F04.19005.19005.3 0.000264 16/44 K.REELITNWEQIR.T "sp|Q13813|SPTN1_HUMAN,tr|A0A0D9SF54|A0A0D9SF54_HUMAN,tr|A0A0D9SGF6|A0A0D9SGF6_HUMAN" 3 1585.8213 1.6 52420 19005 3 1585.811966 529.6144 "Spectrin alpha chain, non-erythrocytic 1 OS=Homo sapiens OX=9606 GN=SPTAN1 PE=1 SV=3" 4.79 3177.7 - 1.50E+06 - - - -5.8575 - 3.175 0.511 - 494.5 1 2 0 -0.0093 12 0 0 0 1.92E+07 1.20E+07 - - - 7.4369 0.9946 221125_WJC_METTL3_EV_vs_WT_F04.19014.19014.3 0.0195 13/48 K.MFVGGLSWDTSK[136.11]K[136.11].D "sp|Q99729|ROAA_HUMAN,tr|D6R9P3|D6R9P3_HUMAN,tr|D6RD18|D6RD18_HUMAN,tr|D6RBZ0|D6RBZ0_HUMAN" 4 1470.7512 1.43 52427 19014 3 1470.745521 491.2577 Heterogeneous nuclear ribonucleoprotein A\B OS=Homo sapiens OX=9606 GN=HNRNPAB PE=1 SV=2 8.35 3178.6 - 1.27E+06 - - - -3.8518 - 1.978 0.279 - 160.2 1 2 0 -0.0057 13 0 0 0 1.92E+07 1.34E+07 - - - 3.4983 1 221125_WJC_METTL3_EV_vs_WT_F04.19023.19023.2 8.19E-12 21/30 L.QDDAHPTLVTYADHSK[136.11].L "sp|Q86U44|MTA70_HUMAN,tr|F5H6D8|F5H6D8_HUMAN,tr|H0YFV6|H0YFV6_HUMAN,tr|B4DTN4|B4DTN4_HUMAN" 4 1804.8471 0.001 52434 19023 2 1804.840892 903.4308 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 5.13 3179.5 - 3.78E+06 - - - -3.4629 - 3.509 0.671 - 1074.6 1 1 0 -0.0063 16 0 0 0 0.00E+00 4.69E+07 - - - 7.0813 1 221125_WJC_METTL3_EV_vs_WT_F04.19025.19025.3 5.14E-07 20/72 K.GSLGGGFSSGGFSGGSFSR.G "sp|P13645|K1C10_HUMAN,tr|A0A1B0GVI3|A0A1B0GVI3_HUMAN" 2 1706.7649 1003.65 52436 19025 3 1706.760788 569.9289 "Keratin, type I cytoskeletal 10 OS=Homo sapiens OX=9606 GN=KRT10 PE=1 SV=6" 9.75 3179.8 - 1.70E+06 - - - -2.387 - 3.292 0.579 - 272.5 1 2 0 -0.0041 19 0 0 0 5.68E+08 5.66E+05 - - - 7.9214 1 221125_WJC_METTL3_EV_vs_WT_F04.19029.19029.3 1.42E-09 19/68 R.QHLQATGVSLGGVDLTVR.V "sp|Q13618|CUL3_HUMAN,tr|A0A087WTG3|A0A087WTG3_HUMAN" 2 1850.001 3.79 52440 19029 3 1849.99562 617.6743 Cullin-3 OS=Homo sapiens OX=9606 GN=CUL3 PE=1 SV=2 6.74 3180.3 - 1.17E+06 - - - -2.9135 - 3.357 0.6 - 434.3 1 2 0 -0.0054 18 0 0 0 1.23E+07 3.24E+06 - - - 8.2435 0.9999 221125_WJC_METTL3_EV_vs_WT_F04.19032.19032.3 1.26E-05 17/76 K.GGVSAVAGGVTAVGSAVVNK.V sp|Q8WUH6|TM263_HUMAN 1 1698.9264 0.92 52441 19032 3 1698.923268 567.3161 Transmembrane protein 263 OS=Homo sapiens OX=9606 GN=TMEM263 PE=1 SV=1 8.75 3180.6 - 1.18E+06 - - - -1.8718 - 2.915 0.448 - 318.2 1 2 0 -0.0032 20 0 0 0 4.21E+07 4.58E+07 - - - 6.1294 0.9932 221125_WJC_METTL3_EV_vs_WT_F04.19033.19033.3 8.67E-06 15/44 K.R[166.11]EELITNWEQIR[166.11].T "sp|Q13813|SPTN1_HUMAN,tr|A0A0D9SF54|A0A0D9SF54_HUMAN,tr|A0A0D9SGF6|A0A0D9SGF6_HUMAN" 3 1605.8378 1.6 52442 19033 3 1605.824296 536.2865 "Spectrin alpha chain, non-erythrocytic 1 OS=Homo sapiens OX=9606 GN=SPTAN1 PE=1 SV=3" 4.79 3180.8 - 1.06E+06 - - - -8.4062 - 2.658 0.409 - 464.4 1 2 0 -0.0135 12 0 0 0 1.92E+07 1.20E+07 - - - 5.8059 0.9877 221125_WJC_METTL3_EV_vs_WT_F04.19034.19034.3 3.35E-11 22/64 L.LQDDAHPTLVTYADHSK[136.11].L "sp|Q86U44|MTA70_HUMAN,tr|F5H6D8|F5H6D8_HUMAN,tr|H0YFV6|H0YFV6_HUMAN,tr|B4DTN4|B4DTN4_HUMAN" 4 1917.9312 0.76 52443 19034 3 1917.923103 640.3177 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 5.13 3180.9 - 1.51E+06 - - - -4.2249 - 3.56 0.541 - 634.6 1 1 0 -0.0081 17 0 0 0 1.56E+07 2.05E+07 - - - 7.7772 1 221125_WJC_METTL3_EV_vs_WT_F04.19038.19038.2 1.12E-10 20/36 K.GSLGGGFSSGGFSGGSFSR.G "sp|P13645|K1C10_HUMAN,tr|A0A1B0GVI3|A0A1B0GVI3_HUMAN" 2 1706.7649 999 52446 19038 2 1706.758737 854.3897 "Keratin, type I cytoskeletal 10 OS=Homo sapiens OX=9606 GN=KRT10 PE=1 SV=6" 9.75 3181.4 - 7.61E+07 - - - -3.5887 - 3.873 0.595 - 959.7 1 2 0 -0.0061 19 0 0 0 7.34E+09 0.00E+00 - - - 6.7627 0.9823 221125_WJC_METTL3_EV_vs_WT_F04.19041.19041.2 3.14E-07 14/24 K.LC[160.03]LNIC[160.03]VGESGDR[166.11].L "sp|P62913|RL11_HUMAN,tr|Q5VVC8|Q5VVC8_HUMAN" 2 1501.6893 1.68 52448 19041 2 1501.678873 751.8519 60S ribosomal protein L11 OS=Homo sapiens OX=9606 GN=RPL11 PE=1 SV=2 4.37 3181.7 - 1.73E+06 - - - -6.9222 - 2.865 0.279 - 785.9 1 2 0 -0.0104 13 0 0 0 3.84E+07 2.28E+07 - - - 3.7999 0.9993 221125_WJC_METTL3_EV_vs_WT_F04.19053.19053.3 3.09E-06 15/40 R.NRENVMEDFLK.R sp|O60825|F262_HUMAN 1 1393.666 3.16 52457 19053 3 1393.661763 465.5626 "6-phosphofructo-2-kinase\fructose-2,6-bisphosphatase 2 OS=Homo sapiens OX=9606 GN=PFKFB2 PE=1 SV=2" 4.68 3183 - 1.75E+06 - - - -3.0402 - 2.33 0.465 - 394.1 1 2 1 -0.0042 11 0 0 0 2.78E+07 8.78E+06 - - - 6.1261 1 221125_WJC_METTL3_EV_vs_WT_F04.19057.19057.3 1.19E-08 25/68 K.TNTLAVTGGEDDKAFVWR.L "sp|Q13685|AAMP_HUMAN,tr|C9JG97|C9JG97_HUMAN,tr|C9JEH3|C9JEH3_HUMAN,tr|C9JTS3|C9JTS3_HUMAN" 4 1978.9749 1.18 52459 19057 3 1978.971512 660.6656 Angio-associated migratory cell protein OS=Homo sapiens OX=9606 GN=AAMP PE=1 SV=2 4.56 3183.5 - 3.31E+06 - - - -1.6893 - 4.571 0.661 - 1068.4 1 2 1 -0.0033 18 0 0 0 5.04E+07 4.26E+07 - - - 9.6929 1 221125_WJC_METTL3_EV_vs_WT_F04.19062.19062.2 3.19E-10 18/28 Q.DDAHPTLVTYADHSK[136.11].L "sp|Q86U44|MTA70_HUMAN,tr|F5H6D8|F5H6D8_HUMAN,tr|H0YFV6|H0YFV6_HUMAN,tr|B4DTN4|B4DTN4_HUMAN" 4 1676.7886 0.001 52462 19062 2 1676.784793 839.4016 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 5.13 3184.1 - 1.30E+06 - - - -2.2489 - 3.218 0.625 - 863.7 1 1 0 -0.0038 15 0 0 0 0.00E+00 2.14E+07 - - - 6.5295 1 221125_WJC_METTL3_EV_vs_WT_F04.19067.19067.3 1.51E-06 15/56 K.GGQTHLGLPVFNTVK[136.11].E "sp|P53597|SUCA_HUMAN,tr|A0A494C0D1|A0A494C0D1_HUMAN" 2 1574.866 1.57 52465 19067 3 1574.864005 525.9626 "Succinate--CoA ligase [ADP\GDP-forming] subunit alpha, mitochondrial OS=Homo sapiens OX=9606 GN=SUCLG1 PE=1 SV=4" 8.76 3184.7 - 1.69E+06 - - - -1.2839 - 2.8 0.442 - 334.6 1 2 0 -0.002 15 0 0 0 1.13E+08 7.20E+07 - - - 6.154 1 221125_WJC_METTL3_EV_vs_WT_F04.19069.19069.2 8.12E-13 17/26 K.C[160.03]PNPTC[160.03]ENMNFSWR[166.11].N "sp|P35637|FUS_HUMAN,tr|H3BPE7|H3BPE7_HUMAN" 2 1821.7261 1.44 52467 19069 2 1821.724295 911.8703 RNA-binding protein FUS OS=Homo sapiens OX=9606 GN=FUS PE=1 SV=1 5.99 3185 - 1.84E+06 - - - -0.9716 - 3.249 0.827 - 1140.5 1 2 0 -0.0018 14 0 0 0 2.01E+08 1.40E+08 - - - 8.1057 1 221125_WJC_METTL3_EV_vs_WT_F04.19073.19073.3 5.04E-09 15/48 R.DLSYC[160.03]LSGMYDHR[166.11].Y sp|P52597|HNRPF_HUMAN 1 1625.6842 0.65 52469 19073 3 1625.680208 542.902 Heterogeneous nuclear ribonucleoprotein F OS=Homo sapiens OX=9606 GN=HNRNPF PE=1 SV=3 5.21 3185.5 - 6.71E+06 - - - -2.4451 - 2.538 0.701 - 239.2 1 2 0 -0.004 13 0 0 0 6.26E+07 9.70E+07 - - - 8.8796 0.9999 221125_WJC_METTL3_EV_vs_WT_F04.19074.19074.2 6.58E-07 15/24 R.DPTAEQFQEELEK.F sp|P31944|CASPE_HUMAN 1 1562.71 55.01 52470 19074 2 1562.708729 782.3623 Caspase-14 OS=Homo sapiens OX=9606 GN=CASP14 PE=1 SV=2 3.91 3185.6 - 3.59E+06 - - - -0.8344 - 2.343 0.544 - 245.9 1 2 0 -0.0013 13 0 0 0 1.30E+08 2.36E+06 - - - 5.2438 1 221125_WJC_METTL3_EV_vs_WT_F04.19076.19076.2 2.73E-14 18/26 K.C[160.03]PNPTC[160.03]ENMNFSWR.N "sp|P35637|FUS_HUMAN,tr|H3BPE7|H3BPE7_HUMAN" 2 1811.7178 1.44 52472 19076 2 1811.716049 906.8662 RNA-binding protein FUS OS=Homo sapiens OX=9606 GN=FUS PE=1 SV=1 5.99 3185.8 - 2.72E+06 - - - -0.9637 - 3.172 0.814 - 1238.7 1 2 0 -0.0017 14 0 0 0 2.01E+08 1.40E+08 - - - 7.9495 1 221125_WJC_METTL3_EV_vs_WT_F04.19080.19080.3 2.09E-06 21/60 K.SGYAFVDC[160.03]PDEHWAMK.A sp|Q9NZI8|IF2B1_HUMAN 1 1911.792 1.25 52474 19080 3 1911.785452 638.2713 Insulin-like growth factor 2 mRNA-binding protein 1 OS=Homo sapiens OX=9606 GN=IGF2BP1 PE=1 SV=2 4.53 3186.3 - 2.17E+06 - - - -3.4277 - 3.491 0.624 - 319.2 1 2 0 -0.0066 16 0 0 0 6.63E+07 5.28E+07 - - - 8.703 1 221125_WJC_METTL3_EV_vs_WT_F04.19082.19082.3 3.54E-08 18/60 K.SGYAFVDC[160.03]PDEHWAMK[136.11].A sp|Q9NZI8|IF2B1_HUMAN 1 1919.8062 1.25 52476 19082 3 1919.804024 640.9427 Insulin-like growth factor 2 mRNA-binding protein 1 OS=Homo sapiens OX=9606 GN=IGF2BP1 PE=1 SV=2 4.53 3186.5 - 2.51E+06 - - - -1.1361 - 3.461 0.653 - 243.4 1 2 0 -0.0022 16 0 0 0 6.63E+07 5.28E+07 - - - 9.0054 1 221125_WJC_METTL3_EV_vs_WT_F04.19083.19083.3 1.37E-09 15/52 K.C[160.03]PNPTC[160.03]ENMNFSWR.N "sp|P35637|FUS_HUMAN,tr|H3BPE7|H3BPE7_HUMAN" 2 1811.7178 1.49 52477 19083 3 1811.714919 604.9132 RNA-binding protein FUS OS=Homo sapiens OX=9606 GN=FUS PE=1 SV=1 5.99 3186.7 - 1.75E+06 - - - -1.5874 - 3.118 0.718 - 367.2 1 2 0 -0.0029 14 0 0 0 5.40E+07 3.64E+07 - - - 9.5663 1 221125_WJC_METTL3_EV_vs_WT_F04.19092.19092.3 0.000182 18/48 R.DLSYC[160.03]LSGMYDHR.Y sp|P52597|HNRPF_HUMAN 1 1615.6759 0.64 52484 19092 3 1615.673116 539.5659 Heterogeneous nuclear ribonucleoprotein F OS=Homo sapiens OX=9606 GN=HNRNPF PE=1 SV=3 5.21 3187.8 - 4.41E+06 - - - -1.7312 - 2.788 0.554 - 394 1 2 0 -0.0028 13 0 0 0 6.24E+07 9.70E+07 - - - 7.4957 1 221125_WJC_METTL3_EV_vs_WT_F04.19095.19095.4 4.23E-07 25/102 K.YVATLGVEVHPLVFHTNR[166.11].G "sp|P62826|RAN_HUMAN,tr|H0YFC6|H0YFC6_HUMAN,tr|B5MDF5|B5MDF5_HUMAN,tr|J3KQE5|J3KQE5_HUMAN,tr|F5H018|F5H018_HUMAN" 5 2061.1035 0.65 52487 19095 4 2061.101919 516.2832 GTP-binding nuclear protein Ran OS=Homo sapiens OX=9606 GN=RAN PE=1 SV=3 6.92 3188.1 - 6.12E+06 - - - -0.7743 - 3.479 0.522 - 438.5 1 2 0 -0.0016 18 0 0 0 4.72E+07 7.24E+07 - - - 4.1961 1 221125_WJC_METTL3_EV_vs_WT_F04.19097.19097.3 5.15E-10 23/68 K.YVATLGVEVHPLVFHTNR[166.11].G "sp|P62826|RAN_HUMAN,tr|H0YFC6|H0YFC6_HUMAN,tr|B5MDF5|B5MDF5_HUMAN,tr|J3KQE5|J3KQE5_HUMAN,tr|F5H018|F5H018_HUMAN" 5 2061.1035 0.74 52489 19097 3 2061.097458 688.0418 GTP-binding nuclear protein Ran OS=Homo sapiens OX=9606 GN=RAN PE=1 SV=3 6.92 3188.3 - 1.82E+06 - - - -2.9387 - 4.033 0.565 - 555 1 2 0 -0.0061 18 0 0 0 1.19E+07 1.60E+07 - - - 8.31 1 221125_WJC_METTL3_EV_vs_WT_F04.19100.19100.3 1.12E-09 24/68 K.YVATLGVEVHPLVFHTNR.G "sp|P62826|RAN_HUMAN,tr|H0YFC6|H0YFC6_HUMAN,tr|B5MDF5|B5MDF5_HUMAN,tr|J3KQE5|J3KQE5_HUMAN,tr|F5H018|F5H018_HUMAN" 5 2051.0952 0.74 52492 19100 3 2051.093835 684.7057 GTP-binding nuclear protein Ran OS=Homo sapiens OX=9606 GN=RAN PE=1 SV=3 6.92 3188.7 - 1.47E+06 - - - -0.6874 - 4.413 0.608 - 565.2 1 2 0 -0.0014 18 0 0 0 1.19E+07 1.60E+07 - - - 9.0149 0.9999 221125_WJC_METTL3_EV_vs_WT_F04.19102.19102.3 2.54E-06 15/56 R.FKLTETLSEDTLAGR.L "sp|P42694|HELZ_HUMAN,tr|J3QS41|J3QS41_HUMAN,tr|A0A075B6R3|A0A075B6R3_HUMAN" 3 1679.873 0.95 52494 19102 3 1679.87322 560.9649 Probable helicase with zinc finger domain OS=Homo sapiens OX=9606 GN=HELZ PE=1 SV=2 4.68 3189 - 1.36E+06 - - - 0.1214 - 2.64 0.484 - 353.3 1 2 1 0.0002 15 0 0 0 9.87E+06 1.03E+07 - - - 6.4692 1 221125_WJC_METTL3_EV_vs_WT_F04.19103.19103.2 2.93E-07 17/38 K.GGVSAVAGGVTAVGSAVVNK.V sp|Q8WUH6|TM263_HUMAN 1 1698.9264 36.73 52495 19103 2 1698.923789 850.4705 Transmembrane protein 263 OS=Homo sapiens OX=9606 GN=TMEM263 PE=1 SV=1 8.75 3189.1 - 982043 - - - -1.5651 - 3.029 0.628 - 441.1 1 2 0 -0.0027 20 0 0 0 2.20E+07 5.99E+05 - - - 6.4032 1 221125_WJC_METTL3_EV_vs_WT_F04.19106.19106.3 7.56E-09 16/72 K.VQGGALEDSQLVAGVAFK[136.11]K[136.11].T sp|Q99832|TCPH_HUMAN 1 1932.0651 0.14 52496 19106 3 1932.062119 645.029 T-complex protein 1 subunit eta OS=Homo sapiens OX=9606 GN=CCT7 PE=1 SV=2 6.04 3189.5 - 7.56E+06 - - - -1.5569 - 3.503 0.596 - 275.2 1 2 0 -0.003 19 0 0 0 1.47E+07 1.07E+08 - - - 8.2639 1 221125_WJC_METTL3_EV_vs_WT_F04.19107.19107.3 8.77E-12 17/68 R.KVPGVTAIELDEDTGTFR.L "sp|P51114|FXR1_HUMAN,tr|E7EU85|E7EU85_HUMAN,tr|E9PFF5|E9PFF5_HUMAN,tr|B4DXZ6|B4DXZ6_HUMAN" 4 1946.9949 1.47 52497 19107 3 1946.992402 650.0056 Fragile X mental retardation syndrome-related protein 1 OS=Homo sapiens OX=9606 GN=FXR1 PE=1 SV=3 4.32 3189.5 - 4.99E+06 - - - -1.2943 - 3.124 0.633 - 385 1 2 0 -0.0025 18 0 0 0 7.32E+07 4.97E+07 - - - 8.4331 0.9999 221125_WJC_METTL3_EV_vs_WT_F04.19109.19109.3 0.000224 15/44 R.GMQDLVEDFKNK.Y sp|P02538|K2C6A_HUMAN 1 1422.6813 87.75 52499 19109 3 1422.679223 475.2344 "Keratin, type II cytoskeletal 6A OS=Homo sapiens OX=9606 GN=KRT6A PE=1 SV=3" 4.56 3189.6 - 4.66E+06 - - - -1.4705 - 2.667 0.497 - 204.4 1 2 1 -0.0021 12 0 0 0 3.64E+07 4.15E+05 - - - 6.7995 1 221125_WJC_METTL3_EV_vs_WT_F04.19110.19110.3 1.25E-08 15/68 R.K[136.11]VPGVTAIELDEDTGTFR[166.11].L "sp|P51114|FXR1_HUMAN,tr|E7EU85|E7EU85_HUMAN,tr|E9PFF5|E9PFF5_HUMAN,tr|B4DXZ6|B4DXZ6_HUMAN" 4 1965.0174 1.47 52500 19110 3 1965.01512 656.0131 Fragile X mental retardation syndrome-related protein 1 OS=Homo sapiens OX=9606 GN=FXR1 PE=1 SV=3 4.32 3189.7 - 4.53E+06 - - - -1.1562 - 2.956 0.598 - 354.7 1 2 0 -0.0023 18 0 0 0 7.32E+07 4.97E+07 - - - 7.9053 1 221125_WJC_METTL3_EV_vs_WT_F04.19112.19112.3 2.47E-11 18/60 K.K[136.11]YEQGFITDPVVLSPK[136.11].D "sp|P12268|IMDH2_HUMAN,tr|A0A7I2YQK5|A0A7I2YQK5_HUMAN,tr|H0Y4R1|H0Y4R1_HUMAN,tr|A0A7I2V2T3|A0A7I2V2T3_HUMAN,tr|E7ETK5|E7ETK5_HUMAN" 5 1836.0004 0.73 52502 19112 3 1836.002239 613.0074 Inosine-5'-monophosphate dehydrogenase 2 OS=Homo sapiens OX=9606 GN=IMPDH2 PE=1 SV=2 6.07 3189.8 - 3.70E+06 - - - 1.0011 - 3.403 0.643 - 559.5 1 2 0 0.0018 16 0 0 0 4.16E+07 5.69E+07 - - - 8.8506 0.998 221125_WJC_METTL3_EV_vs_WT_F04.19114.19114.3 8.57E-08 22/68 H.SSTFDAGAGIALNDHFVK[136.11].L "sp|P04406|G3P_HUMAN,tr|E7EUT5|E7EUT5_HUMAN" 2 1856.9148 1.08 52504 19114 3 1856.911056 619.9789 Glyceraldehyde-3-phosphate dehydrogenase OS=Homo sapiens OX=9606 GN=GAPDH PE=1 SV=3 5.19 3190 - 2.33E+06 - - - -2.0308 - 3.996 0.557 - 647.1 1 1 0 -0.0038 18 0 0 0 2.90E+07 2.67E+07 - - - 8.1985 1 221125_WJC_METTL3_EV_vs_WT_F04.19115.19115.2 7.88E-07 19/34 G.SLGGGFSSGGFSGGSFSR.G "sp|P13645|K1C10_HUMAN,tr|A0A1B0GVI3|A0A1B0GVI3_HUMAN" 2 1649.7434 999 52505 19115 2 1649.742386 825.879 "Keratin, type I cytoskeletal 10 OS=Homo sapiens OX=9606 GN=KRT10 PE=1 SV=6" 9.47 3190.1 - 1.98E+06 - - - -0.6134 - 3.56 0.659 - 999.8 1 1 0 -0.001 18 0 0 0 1.76E+07 0.00E+00 - - - 7.0298 1 221125_WJC_METTL3_EV_vs_WT_F04.19118.19118.2 2.15E-07 14/32 K.TELEDTLDSTAAQQELR.S sp|P35579|MYH9_HUMAN 1 1918.912 3.68 52508 19118 2 1918.902405 960.4633 Myosin-9 OS=Homo sapiens OX=9606 GN=MYH9 PE=1 SV=4 3.83 3190.5 - 1.02E+06 - - - -4.9898 - 3.075 0.62 - 407.2 1 2 0 -0.0096 17 0 0 0 4.65E+07 1.26E+07 - - - 6.379 1 221125_WJC_METTL3_EV_vs_WT_F04.19119.19119.2 2.92E-10 16/30 A.DDEVDVDGTVEEDLGK.S "sp|P14625|ENPL_HUMAN,tr|A0A7P0Z4B4|A0A7P0Z4B4_HUMAN,tr|A0A7P0TAC2|A0A7P0TAC2_HUMAN,tr|A0A7P0Z405|A0A7P0Z405_HUMAN,tr|A0A7P0T823|A0A7P0T823_HUMAN,tr|A0A7P0TAG4|A0A7P0TAG4_HUMAN,tr|A0A7P0TAE1|A0A7P0TAE1_HUMAN,tr|H0YIV0|H0YIV0_HUMAN,tr|A0A7P0T8C8|A0A7P0T8C8_HUMAN,tr|A0A7P0T8R3|A0A7P0T8R3_HUMAN,tr|A0A7P0T885|A0A7P0T885_HUMAN,tr|A0A7P0TAY2|A0A7P0TAY2_HUMAN,tr|A0A087WT78|A0A087WT78_HUMAN,tr|A0A7P0TBC2|A0A7P0TBC2_HUMAN,tr|A0A7P0TAT8|A0A7P0TAT8_HUMAN" 15 1733.7479 1.21 52509 19119 2 1733.744656 867.8812 Endoplasmin OS=Homo sapiens OX=9606 GN=HSP90B1 PE=1 SV=1 3.54 3190.6 - 999506 - - - -1.8907 - 3.273 0.733 - 776 1 1 0 -0.0033 16 0 0 0 1.02E+07 8.38E+06 - - - 7.369 0.9993 221125_WJC_METTL3_EV_vs_WT_F04.19121.19121.3 0.0168 Oct-48 K.ANDLTHSLSSYLK.E "sp|Q9BQ75|CMS1_HUMAN,tr|C9J384|C9J384_HUMAN,tr|H7C515|H7C515_HUMAN" 3 1447.7307 0.54 52511 19121 3 1447.729058 483.5842 Protein CMSS1 OS=Homo sapiens OX=9606 GN=CMSS1 PE=1 SV=2 6.79 3190.9 - 705512 - - - -1.1397 - 1.876 0.299 - 88.5 1 2 0 -0.0016 13 0 0 0 5.61E+06 1.04E+07 - - - 3.5789 0.9999 221125_WJC_METTL3_EV_vs_WT_F04.19122.19122.3 2.47E-07 16/44 R.LPVDLAEELGHR.D "sp|P42771|CDN2A_HUMAN,tr|K7ENC6|K7ENC6_HUMAN,tr|J3QRG6|J3QRG6_HUMAN,tr|K7ES20|K7ES20_HUMAN" 4 1347.7147 0.65 52512 19122 3 1347.71863 450.2455 Cyclin-dependent kinase inhibitor 2A OS=Homo sapiens OX=9606 GN=CDKN2A PE=1 SV=2 4.65 3191 - 701892 - - - 2.9428 - 2.843 0.538 - 321.8 1 2 0 0.004 12 0 0 0 6.12E+06 9.35E+06 - - - 7.4333 0.9999 221125_WJC_METTL3_EV_vs_WT_F04.19124.19124.2 3.86E-11 15/32 K.TELEDTLDSTAAQQELR[166.11].S sp|P35579|MYH9_HUMAN 1 1928.9202 3.85 52514 19124 2 1928.919905 965.4674 Myosin-9 OS=Homo sapiens OX=9606 GN=MYH9 PE=1 SV=4 3.83 3191.3 - 622482 - - - -0.1789 - 3.293 0.467 - 650.8 1 2 0 -0.0003 17 0 0 0 4.61E+07 1.20E+07 - - - 5.4202 0.9982 221125_WJC_METTL3_EV_vs_WT_F04.19129.19129.3 5.30E-07 14/68 H.SSTFDAGAGIALNDHFVK.L "sp|P04406|G3P_HUMAN,tr|E7EUT5|E7EUT5_HUMAN" 2 1848.9006 1.08 52517 19129 3 1848.90162 617.3075 Glyceraldehyde-3-phosphate dehydrogenase OS=Homo sapiens OX=9606 GN=GAPDH PE=1 SV=3 5.19 3191.8 - 4.58E+06 - - - 0.5371 - 3.152 0.527 - 207 1 1 0 0.001 18 0 0 0 2.90E+07 2.67E+07 - - - 7.274 1 221125_WJC_METTL3_EV_vs_WT_F04.19130.19130.3 9.34E-14 21/68 R.GKPPPLLPSVLGPAGGDR.E "sp|Q8IY67|RAVR1_HUMAN,tr|E9PAU2|E9PAU2_HUMAN,tr|A0A087WZ13|A0A087WZ13_HUMAN" 3 1726.973 0.99 52518 19130 3 1726.972301 576.6649 Ribonucleoprotein PTB-binding 1 OS=Homo sapiens OX=9606 GN=RAVER1 PE=1 SV=1 8.75 3191.8 - 3.32E+06 - - - -0.4071 - 3.622 0.652 - 443.3 1 2 0 -0.0007 18 0 0 0 2.35E+08 2.38E+08 - - - 9.0138 0.9999 221125_WJC_METTL3_EV_vs_WT_F04.19131.19131.3 2.70E-07 17/52 K.IAILTC[160.03]PFEPPK[136.11]PK[136.11].T "sp|P48643|TCPE_HUMAN,tr|E9PCA1|E9PCA1_HUMAN,tr|B7ZAR1|B7ZAR1_HUMAN,tr|E7ENZ3|E7ENZ3_HUMAN" 4 1625.9186 0.76 52519 19131 3 1625.919387 542.9801 T-complex protein 1 subunit epsilon OS=Homo sapiens OX=9606 GN=CCT5 PE=1 SV=1 8.2 3191.9 - 3.28E+06 - - - 0.4926 - 2.87 0.353 - 389 1 2 0 0.0008 14 0 0 0 1.64E+08 2.14E+08 - - - 5.2772 1 221125_WJC_METTL3_EV_vs_WT_F04.19132.19132.2 1.74E-11 18/32 K.VWLDPNETNEIANANSR.Q "sp|P84098|RL19_HUMAN,tr|A0A7I2V638|A0A7I2V638_HUMAN,tr|J3KTE4|J3KTE4_HUMAN,tr|A0A7I2V2L0|A0A7I2V2L0_HUMAN,tr|A0A7I2YQG2|A0A7I2YQG2_HUMAN,tr|J3QR09|J3QR09_HUMAN,tr|A0A7I2V512|A0A7I2V512_HUMAN,tr|A0A7I2V4U6|A0A7I2V4U6_HUMAN" 8 1941.9181 1.09 52520 19132 2 1941.918592 971.9663 60S ribosomal protein L19 OS=Homo sapiens OX=9606 GN=RPL19 PE=1 SV=1 4.14 3191.9 - 3.11E+06 - - - 0.2698 - 3.295 0.684 - 878.3 1 2 0 0.0005 17 0 0 0 1.15E+08 1.06E+08 - - - 7.0244 1 221125_WJC_METTL3_EV_vs_WT_F04.19134.19134.3 3.73E-08 16/56 K.TGENVEDAFLEAAK[136.11]K[136.11].L "sp|P61106|RAB14_HUMAN,tr|X6RFL8|X6RFL8_HUMAN" 2 1636.8279 1.02 52522 19134 3 1636.8275 546.6166 Ras-related protein Rab-14 OS=Homo sapiens OX=9606 GN=RAB14 PE=1 SV=4 4.41 3192.1 - 2.12E+06 - - - -0.2542 - 3.02 0.605 - 306.3 1 2 0 -0.0004 15 0 0 0 2.00E+07 1.96E+07 - - - 8.1691 1 221125_WJC_METTL3_EV_vs_WT_F04.19136.19136.3 8.10E-10 23/80 R.GQVGGDVNVEMDAAPGVDLSR.L sp|P02533|K1C14_HUMAN 1 2084.9797 537.82 52524 19136 3 2084.975889 696.0005 "Keratin, type I cytoskeletal 14 OS=Homo sapiens OX=9606 GN=KRT14 PE=1 SV=4" 3.84 3192.2 - 1.74E+06 - - - -1.8192 - 4.056 0.657 - 481.8 1 2 0 -0.0038 21 0 0 0 6.98E+08 1.30E+06 - - - 9.2208 0.9999 221125_WJC_METTL3_EV_vs_WT_F04.19138.19138.3 0.000127 15/40 R.DLTQMADELR[166.11]R[166.11].H "sp|P41227|NAA10_HUMAN,tr|C9JN83|C9JN83_HUMAN" 2 1366.6778 0.51 52526 19138 3 1366.675872 456.5665 N-alpha-acetyltransferase 10 OS=Homo sapiens OX=9606 GN=NAA10 PE=1 SV=1 4.56 3192.4 - 1.55E+06 - - - -1.4027 - 2.326 0.403 - 313 1 2 0 -0.0019 11 0 0 0 9.36E+06 1.84E+07 - - - 5.4306 1 221125_WJC_METTL3_EV_vs_WT_F04.19142.19142.3 7.18E-10 16/52 R.YEDFSNLGTTHLLR[166.11].L "sp|P22695|QCR2_HUMAN,tr|H3BP04|H3BP04_HUMAN,tr|H3BUE4|H3BUE4_HUMAN,tr|H3BUI9|H3BUI9_HUMAN,tr|H3BRG4|H3BRG4_HUMAN,tr|H3BSJ9|H3BSJ9_HUMAN,tr|A0A087WVZ4|A0A087WVZ4_HUMAN" 7 1674.8241 1.23 52530 19142 3 1674.824704 559.282 "Cytochrome b-c1 complex subunit 2, mitochondrial OS=Homo sapiens OX=9606 GN=UQCRC2 PE=1 SV=3" 5.32 3192.9 - 852980 - - - 0.3576 - 2.661 0.611 - 230.1 1 2 0 0.0006 14 0 0 0 8.33E+06 6.76E+06 - - - 7.9528 0.9998 221125_WJC_METTL3_EV_vs_WT_F04.19143.19143.3 0.000137 14/52 R.IDQVNQLLELDHQK.R "sp|P61201|CSN2_HUMAN,tr|B4DIH5|B4DIH5_HUMAN" 2 1691.8842 0.79 52531 19143 3 1691.882829 564.9687 COP9 signalosome complex subunit 2 OS=Homo sapiens OX=9606 GN=COPS2 PE=1 SV=1 4.54 3193 - 852196 - - - -0.8393 - 2.565 0.333 - 225.5 1 2 0 -0.0014 14 0 0 0 5.72E+06 7.25E+06 - - - 4.7555 0.9999 221125_WJC_METTL3_EV_vs_WT_F04.19147.19147.3 6.22E-05 Dec-60 R.AK[136.11]FEEYGPVIEC[160.03]DIVK[136.11].D "sp|Q9BWF3|RBM4_HUMAN,sp|Q9BQ04|RBM4B_HUMAN,tr|E9PM61|E9PM61_HUMAN,tr|D6R9K7|D6R9K7_HUMAN,tr|J3QRR5|J3QRR5_HUMAN,tr|E9PB51|E9PB51_HUMAN,tr|U3KQD5|U3KQD5_HUMAN,tr|E9PLB0|E9PLB0_HUMAN" 8 1911.9623 1.62 52533 19147 3 1911.960985 638.328 RNA-binding protein 4 OS=Homo sapiens OX=9606 GN=RBM4 PE=1 SV=1 4.41 3193.5 - 6.77E+06 - - - -0.6888 - 2.188 0.532 - 147.7 1 2 1 -0.0013 16 0 0 0 3.35E+08 2.07E+08 - - - 6.4799 1 221125_WJC_METTL3_EV_vs_WT_F04.19148.19148.3 3.34E-11 18/68 R.GK[136.11]PPPLLPSVLGPAGGDR[166.11].E "sp|Q8IY67|RAVR1_HUMAN,tr|E9PAU2|E9PAU2_HUMAN,tr|A0A087WZ13|A0A087WZ13_HUMAN" 3 1744.9955 0.99 52534 19148 3 1744.993571 582.6724 Ribonucleoprotein PTB-binding 1 OS=Homo sapiens OX=9606 GN=RAVER1 PE=1 SV=1 8.75 3193.6 - 6.63E+06 - - - -1.0905 - 3.22 0.661 - 365.8 1 2 0 -0.0019 18 0 0 0 2.35E+08 2.38E+08 - - - 8.8208 1 221125_WJC_METTL3_EV_vs_WT_F04.19149.19149.2 8.36E-08 18/32 K.VWLDPNETNEIANANSR[166.11].Q "sp|P84098|RL19_HUMAN,tr|A0A7I2V638|A0A7I2V638_HUMAN,tr|J3KTE4|J3KTE4_HUMAN,tr|A0A7I2V2L0|A0A7I2V2L0_HUMAN,tr|A0A7I2YQG2|A0A7I2YQG2_HUMAN,tr|J3QR09|J3QR09_HUMAN,tr|A0A7I2V512|A0A7I2V512_HUMAN,tr|A0A7I2V4U6|A0A7I2V4U6_HUMAN" 8 1951.9263 1.09 52535 19149 2 1951.923543 976.9704 60S ribosomal protein L19 OS=Homo sapiens OX=9606 GN=RPL19 PE=1 SV=1 4.14 3193.6 - 6.51E+06 - - - -1.4319 - 3.404 0.604 - 815.9 1 2 0 -0.0028 17 0 0 0 1.15E+08 1.06E+08 - - - 6.5129 1 221125_WJC_METTL3_EV_vs_WT_F04.19150.19150.2 5.47E-17 23/40 R.GQVGGDVNVEMDAAPGVDLSR.L sp|P02533|K1C14_HUMAN 1 2084.9797 246.43 52536 19150 2 2084.978464 1043.4971 "Keratin, type I cytoskeletal 14 OS=Homo sapiens OX=9606 GN=KRT14 PE=1 SV=4" 3.84 3193.7 - 4.75E+06 - - - -0.5842 - 4.114 0.75 - 1090.3 1 2 0 -0.0012 21 0 0 0 4.66E+08 1.89E+06 - - - 8.0575 0.9999 221125_WJC_METTL3_EV_vs_WT_F04.19154.19154.3 4.77E-05 15/40 R.DLTQMADELRR.H "sp|P41227|NAA10_HUMAN,tr|C9JN83|C9JN83_HUMAN" 2 1346.6612 0.51 52540 19154 3 1346.659978 449.8944 N-alpha-acetyltransferase 10 OS=Homo sapiens OX=9606 GN=NAA10 PE=1 SV=1 4.56 3194.1 - 1.10E+06 - - - -0.9438 - 2.127 0.449 - 317.8 1 2 0 -0.0013 11 0 0 0 9.36E+06 1.84E+07 - - - 5.6896 0.812 221125_WJC_METTL3_EV_vs_WT_F04.19155.19155.2 4.78E-05 17/30 R.AKFEEYGPVIEC[160.03]DIVK.D "sp|Q9BWF3|RBM4_HUMAN,sp|Q9BQ04|RBM4B_HUMAN,tr|E9PM61|E9PM61_HUMAN,tr|D6R9K7|D6R9K7_HUMAN,tr|J3QRR5|J3QRR5_HUMAN,tr|E9PB51|E9PB51_HUMAN,tr|U3KQD5|U3KQD5_HUMAN,tr|E9PLB0|E9PLB0_HUMAN" 8 1895.9339 1.39 52541 19155 2 1895.948063 948.9742 RNA-binding protein 4 OS=Homo sapiens OX=9606 GN=RBM4 PE=1 SV=1 4.41 3194.2 - 860181 - - - 7.4691 - 3.117 0.275 - 743.8 1 2 1 0.0142 16 0 0 0 1.31E+07 9.42E+06 - - - 3.8628 0.8635 221125_WJC_METTL3_EV_vs_WT_F04.19157.19157.2 0.0309 Sep-34 R.IGSSLYALGTQDSTDIC[160.03]K.F "sp|Q9UNH7|SNX6_HUMAN,tr|A0A0A0MRI2|A0A0A0MRI2_HUMAN" 2 1927.9197 3.6 52543 19157 2 1928.92157 964.9671 Sorting nexin-6 OS=Homo sapiens OX=9606 GN=SNX6 PE=1 SV=1 4.21 3194.5 - 675864 - - - 519.6596 - 1.553 0.211 - 161 1 2 0 1.0019 18 0 0 0 1.04E+07 2.90E+06 - - - 1.3671 1 221125_WJC_METTL3_EV_vs_WT_F04.19159.19159.2 5.79E-10 30-Dec A.DDEVDVDGTVEEDLGK[136.11].S "sp|P14625|ENPL_HUMAN,tr|A0A7P0Z4B4|A0A7P0Z4B4_HUMAN,tr|A0A7P0TAC2|A0A7P0TAC2_HUMAN,tr|A0A7P0Z405|A0A7P0Z405_HUMAN,tr|A0A7P0T823|A0A7P0T823_HUMAN,tr|A0A7P0TAG4|A0A7P0TAG4_HUMAN,tr|A0A7P0TAE1|A0A7P0TAE1_HUMAN,tr|H0YIV0|H0YIV0_HUMAN,tr|A0A7P0T8C8|A0A7P0T8C8_HUMAN,tr|A0A7P0T8R3|A0A7P0T8R3_HUMAN,tr|A0A7P0T885|A0A7P0T885_HUMAN,tr|A0A7P0TAY2|A0A7P0TAY2_HUMAN,tr|A0A087WT78|A0A087WT78_HUMAN,tr|A0A7P0TBC2|A0A7P0TBC2_HUMAN,tr|A0A7P0TAT8|A0A7P0TAT8_HUMAN" 15 1741.7621 1.21 52545 19159 2 1741.761729 871.8883 Endoplasmin OS=Homo sapiens OX=9606 GN=HSP90B1 PE=1 SV=1 3.54 3194.7 - 521786 - - - -0.2325 - 2.734 0.734 - 403.1 1 1 0 -0.0004 16 0 0 0 1.02E+07 8.38E+06 - - - 6.9349 1 221125_WJC_METTL3_EV_vs_WT_F04.19163.19163.3 4.00E-10 16/64 K.VWLDPNETNEIANANSR.Q "sp|P84098|RL19_HUMAN,tr|A0A7I2V638|A0A7I2V638_HUMAN,tr|J3KTE4|J3KTE4_HUMAN,tr|A0A7I2V2L0|A0A7I2V2L0_HUMAN,tr|A0A7I2YQG2|A0A7I2YQG2_HUMAN,tr|J3QR09|J3QR09_HUMAN,tr|A0A7I2V512|A0A7I2V512_HUMAN,tr|A0A7I2V4U6|A0A7I2V4U6_HUMAN" 8 1941.9181 1.33 52547 19163 3 1941.917066 648.3133 60S ribosomal protein L19 OS=Homo sapiens OX=9606 GN=RPL19 PE=1 SV=1 4.14 3195.2 - 6.19E+06 - - - -0.516 - 2.92 0.636 - 282.7 1 2 0 -0.001 17 0 0 0 9.48E+07 7.13E+07 - - - 8.3376 1 221125_WJC_METTL3_EV_vs_WT_F04.19164.19164.3 0.000385 18/64 K.VWLDPNETNEIANANSR[166.11].Q "sp|P84098|RL19_HUMAN,tr|A0A7I2V638|A0A7I2V638_HUMAN,tr|J3KTE4|J3KTE4_HUMAN,tr|A0A7I2V2L0|A0A7I2V2L0_HUMAN,tr|A0A7I2YQG2|A0A7I2YQG2_HUMAN,tr|J3QR09|J3QR09_HUMAN,tr|A0A7I2V512|A0A7I2V512_HUMAN,tr|A0A7I2V4U6|A0A7I2V4U6_HUMAN" 8 1951.9263 1.33 52548 19164 3 1951.926044 651.6494 60S ribosomal protein L19 OS=Homo sapiens OX=9606 GN=RPL19 PE=1 SV=1 4.14 3195.3 - 5.72E+06 - - - -0.1506 - 3.177 0.541 - 408.6 1 2 0 -0.0003 17 0 0 0 9.33E+07 6.99E+07 - - - 7.4918 1 221125_WJC_METTL3_EV_vs_WT_F04.19165.19165.3 3.47E-07 18/72 K.FYQTSVESVDFANAPEESR.K sp|P29508|SPB3_HUMAN 1 2174.9756 129.61 52549 19165 3 2174.974952 725.9992 Serpin B3 OS=Homo sapiens OX=9606 GN=SERPINB3 PE=1 SV=2 4 3195.4 - 5.12E+06 - - - -0.3177 - 3.407 0.588 - 330.3 1 2 0 -0.0007 19 0 0 0 5.96E+07 4.60E+05 - - - 8.1071 0.9769 221125_WJC_METTL3_EV_vs_WT_F04.19166.19166.3 0.891 13/52 K.HEQILVLDPPTDLK.F "sp|Q9P0L0|VAPA_HUMAN,tr|J3QKM9|J3QKM9_HUMAN" 2 1616.8774 2.68 52550 19166 3 1616.884512 539.9664 Vesicle-associated membrane protein-associated protein A OS=Homo sapiens OX=9606 GN=VAPA PE=1 SV=3 4.54 3195.4 - 1.87E+06 - - - 4.4153 - 2.163 0.196 - 202.2 1 2 0 0.0071 14 0 0 0 3.97E+07 1.48E+07 - - - 2.7735 1 221125_WJC_METTL3_EV_vs_WT_F04.19169.19169.3 2.04E-07 18/48 R.KQYPISLVLAPTR.E "sp|O00571|DDX3X_HUMAN,sp|O15523|DDX3Y_HUMAN,tr|A0A2R8YFR4|A0A2R8YFR4_HUMAN,tr|A0A2R8YCW1|A0A2R8YCW1_HUMAN,tr|A0A2R8YDH3|A0A2R8YDH3_HUMAN,tr|A0A2R8YDT5|A0A2R8YDT5_HUMAN,tr|A0A2R8Y645|A0A2R8Y645_HUMAN,tr|A0A2R8YF78|A0A2R8YF78_HUMAN,tr|A0A0D9SFB3|A0A0D9SFB3_HUMAN,tr|A0A2R8YFS5|A0A2R8YFS5_HUMAN,tr|A0A0D9SF53|A0A0D9SF53_HUMAN,tr|A0A2R8Y5G6|A0A2R8Y5G6_HUMAN,tr|A0A2R8Y7T2|A0A2R8Y7T2_HUMAN,tr|A0A0D9SG12|A0A0D9SG12_HUMAN,tr|A0A2U3TZJ9|A0A2U3TZJ9_HUMAN,tr|A0A2R8Y4A4|A0A2R8Y4A4_HUMAN" 16 1484.8715 1.23 52553 19169 3 1484.871782 495.9644 ATP-dependent RNA helicase DDX3X OS=Homo sapiens OX=9606 GN=DDX3X PE=1 SV=3 9.99 3195.8 - 654439 - - - 0.1906 - 3.567 0.583 - 545.6 1 2 0 0.0003 13 0 0 0 3.00E+07 2.44E+07 - - - 8.4878 1 221125_WJC_METTL3_EV_vs_WT_F04.19173.19173.3 9.36E-06 23/72 K.LQEEMLQREEAENTLQSFR.Q "sp|P08670|VIME_HUMAN,tr|B0YJC5|B0YJC5_HUMAN,tr|B0YJC4|B0YJC4_HUMAN" 3 2350.1223 1.67 52555 19173 3 2350.122187 784.3814 Vimentin OS=Homo sapiens OX=9606 GN=VIM PE=1 SV=4 4.33 3196.3 - 3.68E+06 - - - -0.0583 - 4.313 0.552 - 604.9 1 2 1 -0.0001 19 0 0 0 1.82E+08 1.09E+08 - - - 8.2852 1 221125_WJC_METTL3_EV_vs_WT_F04.19174.19174.3 8.44E-09 15/64 K.K[136.11]IFVGGLSANTVVEDVK[136.11].Q "sp|Q96DH6|MSI2H_HUMAN,tr|B4DHE8|B4DHE8_HUMAN,tr|A0A6Q8PF05|A0A6Q8PF05_HUMAN,tr|B4DM51|B4DM51_HUMAN,tr|J3KTC1|J3KTC1_HUMAN" 5 1791.0113 1.58 52556 19174 3 1791.011125 598.011 RNA-binding protein Musashi homolog 2 OS=Homo sapiens OX=9606 GN=MSI2 PE=1 SV=1 6.07 3196.3 - 3.10E+06 - - - -0.0977 - 2.709 0.559 - 317.6 1 2 0 -0.0002 17 0 0 0 5.03E+07 3.20E+07 - - - 7.2899 0.9948 221125_WJC_METTL3_EV_vs_WT_F04.19175.19175.3 7.43E-05 16/68 R.TVVSGLVNHVPLEQMQNR.M "sp|Q12904|AIMP1_HUMAN,tr|A0A804HJ47|A0A804HJ47_HUMAN,tr|A0A5F9ZHC5|A0A5F9ZHC5_HUMAN" 3 2020.0524 1.62 52557 19175 3 2021.061107 674.3581 Aminoacyl tRNA synthase complex-interacting multifunctional protein 1 OS=Homo sapiens OX=9606 GN=AIMP1 PE=1 SV=2 6.41 3196.4 - 2.78E+06 - - - 499.3499 - 2.575 0.457 - 171.4 1 2 0 1.0087 18 0 0 0 4.36E+07 2.70E+07 - - - 5.7109 1 221125_WJC_METTL3_EV_vs_WT_F04.19176.19176.3 6.43E-07 16/72 K.LQEEMLQR[166.11]EEAENTLQSFR[166.11].Q "sp|P08670|VIME_HUMAN,tr|B0YJC5|B0YJC5_HUMAN,tr|B0YJC4|B0YJC4_HUMAN" 3 2370.1389 1.73 52558 19176 3 2370.132657 791.0536 Vimentin OS=Homo sapiens OX=9606 GN=VIM PE=1 SV=4 4.33 3196.4 - 2.55E+06 - - - -2.6188 - 3.785 0.599 - 209.4 1 2 1 -0.0062 19 0 0 0 1.89E+08 1.09E+08 - - - 8.4867 1 221125_WJC_METTL3_EV_vs_WT_F04.19178.19178.3 6.73E-10 14/60 K.KYEQGFITDPVVLSPK.D "sp|P12268|IMDH2_HUMAN,tr|A0A7I2YQK5|A0A7I2YQK5_HUMAN,tr|H0Y4R1|H0Y4R1_HUMAN,tr|A0A7I2V2T3|A0A7I2V2T3_HUMAN,tr|E7ETK5|E7ETK5_HUMAN" 5 1819.972 0.73 52560 19178 3 1819.976655 607.6646 Inosine-5'-monophosphate dehydrogenase 2 OS=Homo sapiens OX=9606 GN=IMPDH2 PE=1 SV=2 6.07 3196.6 - 1.68E+06 - - - 2.5572 - 2.983 0.574 - 325.2 1 2 0 0.0047 16 0 0 0 4.16E+07 5.68E+07 - - - 7.7426 0.9971 221125_WJC_METTL3_EV_vs_WT_F04.19179.19179.3 7.25E-06 20/52 R.RLNAETFGIPLRPN.R "sp|Q8ND56|LS14A_HUMAN,tr|A0A140TA66|A0A140TA66_HUMAN,tr|A0A096LP11|A0A096LP11_HUMAN,tr|A0A140TA76|A0A140TA76_HUMAN,tr|A0A0G2JQ95|A0A0G2JQ95_HUMAN" 5 1596.8736 0.56 52561 19179 3 1596.874047 533.2985 Protein LSM14 homolog A OS=Homo sapiens OX=9606 GN=LSM14A PE=1 SV=3 9.6 3196.7 - 1.33E+06 - - - 0.2643 - 2.883 0.473 - 481.7 1 1 0 0.0004 14 0 0 0 2.96E+07 5.28E+07 - - - 6.6272 0.8735 221125_WJC_METTL3_EV_vs_WT_F04.19180.19180.3 0.000211 Nov-72 R.VADGLPLAASMQEDEQSGR.D sp|O75396|SC22B_HUMAN 1 1972.916 2.28 52562 19180 3 1973.906581 658.6459 Vesicle-trafficking protein SEC22b OS=Homo sapiens OX=9606 GN=SEC22B PE=1 SV=5 3.92 3196.8 - 957965 - - - 502.0802 - 2.496 0.411 - 65.1 1 2 0 0.9906 19 0 0 0 1.94E+07 8.52E+06 - - - 5.0951 0.9999 221125_WJC_METTL3_EV_vs_WT_F04.19181.19181.3 0.00023 13/64 R.ALQQYTLEPSEKPFDLK.S sp|Q9Y678|COPG1_HUMAN 1 2006.0361 0.3 52563 19181 3 2006.032836 669.686 Coatomer subunit gamma-1 OS=Homo sapiens OX=9606 GN=COPG1 PE=1 SV=1 4.68 3196.9 - 870765 - - - -1.6062 - 2.329 0.406 - 184.1 1 2 0 -0.0032 17 0 0 0 9.75E+06 3.21E+07 - - - 5.2014 0.9999 221125_WJC_METTL3_EV_vs_WT_F04.19184.19184.2 8.47E-06 15/26 K.VLEQLTGQTPVFSK[136.11].A "sp|P62913|RL11_HUMAN,tr|Q5VVC8|Q5VVC8_HUMAN" 2 1553.8545 1.13 52566 19184 2 1553.854594 777.9345 60S ribosomal protein L11 OS=Homo sapiens OX=9606 GN=RPL11 PE=1 SV=2 5.97 3197.3 - 562309 - - - 0.0869 - 2.967 0.513 - 877 1 2 0 0.0001 14 0 0 0 1.95E+07 1.72E+07 - - - 5.5591 0.9951 221125_WJC_METTL3_EV_vs_WT_F04.19185.19185.2 0.345 16-Jul R.LLLPGELAK.H "sp|Q8N257|H2B3B_HUMAN,sp|A0A2R8Y619|H2BE1_HUMAN,sp|P33778|H2B1B_HUMAN,sp|Q96A08|H2B1A_HUMAN,sp|Q5QNW6|H2B2F_HUMAN,sp|P58876|H2B1D_HUMAN,sp|Q99880|H2B1L_HUMAN,sp|P62807|H2B1C_HUMAN,sp|Q99877|H2B1N_HUMAN,sp|P57053|H2BFS_HUMAN,sp|P23527|H2B1O_HUMAN,sp|O60814|H2B1K_HUMAN,sp|Q93079|H2B1H_HUMAN,sp|Q99879|H2B1M_HUMAN,sp|Q16778|H2B2E_HUMAN,sp|P06899|H2B1J_HUMAN,tr|U3KQK0|U3KQK0_HUMAN" 17 952.5957 1.39 52567 19185 2 952.596467 477.3051 Histone H2B type 3-B OS=Homo sapiens OX=9606 GN=H2BU1 PE=1 SV=3 6 3197.4 - 491415 - - - 0.7863 - 1.275 0.204 - 129.3 1 2 0 0.0007 9 0 0 0 7.54E+06 5.44E+06 - - - 1.2504 1 221125_WJC_METTL3_EV_vs_WT_F04.19193.19193.3 3.87E-07 16/48 R.K[136.11]QYPISLVLAPTR[166.11].E "sp|O00571|DDX3X_HUMAN,sp|O15523|DDX3Y_HUMAN,tr|A0A2R8YFR4|A0A2R8YFR4_HUMAN,tr|A0A2R8YCW1|A0A2R8YCW1_HUMAN,tr|A0A2R8YDH3|A0A2R8YDH3_HUMAN,tr|A0A2R8YDT5|A0A2R8YDT5_HUMAN,tr|A0A2R8Y645|A0A2R8Y645_HUMAN,tr|A0A2R8YF78|A0A2R8YF78_HUMAN,tr|A0A0D9SFB3|A0A0D9SFB3_HUMAN,tr|A0A2R8YFS5|A0A2R8YFS5_HUMAN,tr|A0A0D9SF53|A0A0D9SF53_HUMAN,tr|A0A2R8Y5G6|A0A2R8Y5G6_HUMAN,tr|A0A2R8Y7T2|A0A2R8Y7T2_HUMAN,tr|A0A0D9SG12|A0A0D9SG12_HUMAN,tr|A0A2U3TZJ9|A0A2U3TZJ9_HUMAN,tr|A0A2R8Y4A4|A0A2R8Y4A4_HUMAN" 16 1502.894 1.14 52573 19193 3 1502.891298 501.9719 ATP-dependent RNA helicase DDX3X OS=Homo sapiens OX=9606 GN=DDX3X PE=1 SV=3 9.99 3198.2 - 1.35E+06 - - - -1.7772 - 3.037 0.542 - 462.3 1 2 0 -0.0027 13 0 0 0 2.78E+07 2.43E+07 - - - 7.5939 1 221125_WJC_METTL3_EV_vs_WT_F04.19195.19195.2 8.82E-11 21/36 K.FYQTSVESVDFANAPEESR.K sp|P29508|SPB3_HUMAN 1 2174.9756 999 52575 19195 2 2174.973757 1088.4951 Serpin B3 OS=Homo sapiens OX=9606 GN=SERPINB3 PE=1 SV=2 4 3198.5 - 1.22E+06 - - - -0.8671 - 4.172 0.728 - 1435.6 1 2 0 -0.0019 19 0 0 0 2.29E+07 0.00E+00 - - - 7.9292 0.9999 221125_WJC_METTL3_EV_vs_WT_F04.19196.19196.2 7.65E-06 15/26 K.VLEQLTGQTPVFSK.A "sp|P62913|RL11_HUMAN,tr|Q5VVC8|Q5VVC8_HUMAN" 2 1545.8403 1.13 52576 19196 2 1545.839477 773.9274 60S ribosomal protein L11 OS=Homo sapiens OX=9606 GN=RPL11 PE=1 SV=2 5.97 3198.6 - 954846 - - - -0.5059 - 2.906 0.488 - 928.4 1 2 0 -0.0008 14 0 0 0 1.95E+07 1.72E+07 - - - 5.3221 0.9996 221125_WJC_METTL3_EV_vs_WT_F04.19197.19197.2 1.43E-08 14/38 K.GTGVVTSVPSDSPDDIAALR[166.11].D "sp|Q9P2J5|SYLC_HUMAN,tr|A0A6I8PIV1|A0A6I8PIV1_HUMAN,tr|A0A6I8PRS0|A0A6I8PRS0_HUMAN,tr|A0A6I8PLB8|A0A6I8PLB8_HUMAN,tr|A0A6I8PIP7|A0A6I8PIP7_HUMAN,tr|A0A6I8PIT3|A0A6I8PIT3_HUMAN,tr|A0A6I8PTV8|A0A6I8PTV8_HUMAN,tr|A0A6I8PRU9|A0A6I8PRU9_HUMAN,tr|A0A6I8PLB3|A0A6I8PLB3_HUMAN,tr|A0A6I8PS05|A0A6I8PS05_HUMAN,tr|B4DER1|B4DER1_HUMAN,tr|A0A6I8PL42|A0A6I8PL42_HUMAN" 12 1965.9883 0.69 52577 19197 2 1965.982273 984.0014 "Leucine--tRNA ligase, cytoplasmic OS=Homo sapiens OX=9606 GN=LARS1 PE=1 SV=2" 3.93 3198.7 - 471419 - - - -3.0504 - 2.846 0.52 - 257.9 1 2 0 -0.006 20 0 0 0 4.87E+06 7.11E+06 - - - 5.4513 0.9972 221125_WJC_METTL3_EV_vs_WT_F04.19198.19198.2 0.0257 Jul-34 R.GKPPPLLPSVLGPAGGDR.E "sp|Q8IY67|RAVR1_HUMAN,tr|E9PAU2|E9PAU2_HUMAN,tr|A0A087WZ13|A0A087WZ13_HUMAN" 3 1726.973 1.13 52578 19198 2 1726.971356 864.4938 Ribonucleoprotein PTB-binding 1 OS=Homo sapiens OX=9606 GN=RAVER1 PE=1 SV=1 8.75 3198.9 - 375470 - - - -0.9543 - 1.658 0.185 - 82.5 1 2 0 -0.0016 18 0 0 0 4.78E+06 4.24E+06 - - - 1.65 1 221125_WJC_METTL3_EV_vs_WT_F04.19200.19200.3 6.21E-06 15/52 K.IAILTC[160.03]PFEPPKPK.T "sp|P48643|TCPE_HUMAN,tr|E9PCA1|E9PCA1_HUMAN,tr|B7ZAR1|B7ZAR1_HUMAN,tr|E7ENZ3|E7ENZ3_HUMAN" 4 1609.8902 0.79 52579 19200 3 1609.889534 537.6373 T-complex protein 1 subunit epsilon OS=Homo sapiens OX=9606 GN=CCT5 PE=1 SV=1 8.2 3199.1 - 3.97E+06 - - - -0.405 - 2.789 0.512 - 276.2 1 2 0 -0.0007 14 0 0 0 1.69E+08 2.14E+08 - - - 6.9739 0.9999 221125_WJC_METTL3_EV_vs_WT_F04.19203.19203.3 2.22E-06 13/64 R.VNTHGIFTISTASMVEK.V "sp|Q92598|HS105_HUMAN,tr|A0A0A0MSM0|A0A0A0MSM0_HUMAN" 2 1833.9295 0.17 52581 19203 3 1833.927534 612.3171 Heat shock protein 105 kDa OS=Homo sapiens OX=9606 GN=HSPH1 PE=1 SV=1 6.72 3199.3 - 1.54E+06 - - - -1.0638 - 2.768 0.397 - 210.1 1 2 0 -0.0019 17 0 0 0 1.85E+07 1.11E+08 - - - 5.5377 0.9995 221125_WJC_METTL3_EV_vs_WT_F04.19205.19205.3 0.0031 15/60 R.SGMSHEEDQLIPNLYR.Y sp|Q6P2Q9|PRP8_HUMAN 1 1887.8785 59.99 52583 19205 3 1887.884685 630.3001 Pre-mRNA-processing-splicing factor 8 OS=Homo sapiens OX=9606 GN=PRPF8 PE=1 SV=2 4.65 3199.6 - 607919 - - - 3.2698 - 2.201 0.41 - 161.7 1 2 0 0.0062 16 0 0 0 8.53E+06 1.42E+05 - - - 5.1336 0.9991 221125_WJC_METTL3_EV_vs_WT_F04.19206.19206.3 0.00294 Sep-52 K.LEDK[136.11]VENLVDQLNK[136.11].S "sp|Q15643|TRIPB_HUMAN,tr|H0YJ97|H0YJ97_HUMAN" 2 1671.9014 1.07 52584 19206 3 1671.902618 558.3077 Thyroid receptor-interacting protein 11 OS=Homo sapiens OX=9606 GN=TRIP11 PE=1 SV=3 4.32 3199.7 - 585790 - - - 0.7189 - 1.985 0.381 - 50.4 1 2 1 0.0012 14 0 0 0 4.42E+06 4.11E+06 - - - 4.6095 1 221125_WJC_METTL3_EV_vs_WT_F04.19207.19207.2 6.92E-09 21/30 R.AK[136.11]FEEYGPVIEC[160.03]DIVK[136.11].D "sp|Q9BWF3|RBM4_HUMAN,sp|Q9BQ04|RBM4B_HUMAN,tr|E9PM61|E9PM61_HUMAN,tr|D6R9K7|D6R9K7_HUMAN,tr|J3QRR5|J3QRR5_HUMAN,tr|E9PB51|E9PB51_HUMAN,tr|U3KQD5|U3KQD5_HUMAN,tr|E9PLB0|E9PLB0_HUMAN" 8 1911.9623 1.39 52585 19207 2 1911.959973 956.9884 RNA-binding protein 4 OS=Homo sapiens OX=9606 GN=RBM4 PE=1 SV=1 4.41 3199.9 - 564830 - - - -1.2181 - 3.382 0.625 - 1257.4 1 2 1 -0.0023 16 0 0 0 1.31E+07 9.42E+06 - - - 6.6522 0.9997 221125_WJC_METTL3_EV_vs_WT_F04.19208.19208.2 5.20E-05 14/32 K.LQPSSSPENSLDPFPPR.L "sp|Q8WWM7|ATX2L_HUMAN,tr|H3BUF6|H3BUF6_HUMAN" 2 1866.9112 1.33 52586 19208 2 1866.906589 934.4629 Ataxin-2-like protein OS=Homo sapiens OX=9606 GN=ATXN2L PE=1 SV=2 4.37 3200 - 410548 - - - -2.4656 - 2.665 0.565 - 438.9 1 2 0 -0.0046 17 0 0 0 6.97E+06 5.25E+06 - - - 5.6225 1 221125_WJC_METTL3_EV_vs_WT_F04.19209.19209.2 6.29E-10 13/36 R.VADGLPLAASMQEDEQSGR.D sp|O75396|SC22B_HUMAN 1 1972.916 2.27 52587 19209 2 1972.917682 987.4653 Vesicle-trafficking protein SEC22b OS=Homo sapiens OX=9606 GN=SEC22B PE=1 SV=5 3.92 3200.1 - 373635 - - - 0.8429 - 2.8 0.685 - 314.9 1 2 0 0.0017 19 0 0 0 5.88E+06 2.59E+06 - - - 6.6313 0.9943 221125_WJC_METTL3_EV_vs_WT_F04.19210.19210.2 0.502 16-Aug R.LLLPGELAK[136.11].H "sp|Q8N257|H2B3B_HUMAN,sp|A0A2R8Y619|H2BE1_HUMAN,sp|P33778|H2B1B_HUMAN,sp|Q96A08|H2B1A_HUMAN,sp|Q5QNW6|H2B2F_HUMAN,sp|P58876|H2B1D_HUMAN,sp|Q99880|H2B1L_HUMAN,sp|P62807|H2B1C_HUMAN,sp|Q99877|H2B1N_HUMAN,sp|P57053|H2BFS_HUMAN,sp|P23527|H2B1O_HUMAN,sp|O60814|H2B1K_HUMAN,sp|Q93079|H2B1H_HUMAN,sp|Q99879|H2B1M_HUMAN,sp|Q16778|H2B2E_HUMAN,sp|P06899|H2B1J_HUMAN,tr|U3KQK0|U3KQK0_HUMAN" 17 960.6099 1.39 52588 19210 2 960.610015 481.3122 Histone H2B type 3-B OS=Homo sapiens OX=9606 GN=H2BU1 PE=1 SV=3 6 3200.3 - 369317 - - - 0.101 - 1.331 0.154 - 140.1 1 2 0 0.0001 9 0 0 0 7.54E+06 5.44E+06 - - - 1.0056 1 221125_WJC_METTL3_EV_vs_WT_F04.19213.19213.3 1.50E-11 23/80 K.GTAGLSQNSTLEVQTLSVAPK.A "sp|Q96QA5|GSDMA_HUMAN,tr|J3KRG2|J3KRG2_HUMAN" 2 2100.1063 67.36 52589 19213 3 2100.10511 701.0427 Gasdermin-A OS=Homo sapiens OX=9606 GN=GSDMA PE=1 SV=4 6 3200.7 - 3.36E+06 - - - -0.549 - 4.049 0.653 - 622.1 1 2 0 -0.0012 21 0 0 0 3.73E+07 5.54E+05 - - - 9.1728 1 221125_WJC_METTL3_EV_vs_WT_F04.19214.19214.3 9.05E-08 15/60 K.VELAQLQEEWNEHNAK.L sp|Q9H307|PININ_HUMAN 1 1936.9279 2.2 52590 19214 3 1936.926945 646.6499 Pinin OS=Homo sapiens OX=9606 GN=PNN PE=1 SV=5 4.48 3200.7 - 3.87E+06 - - - -0.4956 - 2.801 0.571 - 270.8 1 2 0 -0.001 16 0 0 0 6.31E+07 2.87E+07 - - - 7.5486 1 221125_WJC_METTL3_EV_vs_WT_F04.19217.19217.2 3.97E-05 14/28 Q.SVTDTNVILSMDNSR.N sp|P35908|K22E_HUMAN 1 1650.7883 27.18 52593 19217 2 1650.792122 826.4014 "Keratin, type II cytoskeletal 2 epidermal OS=Homo sapiens OX=9606 GN=KRT2 PE=1 SV=2" 4.21 3201.1 - 926905 - - - 2.3153 - 2.901 0.563 - 603.6 1 1 0 0.0038 15 0 0 0 1.03E+07 3.78E+05 - - - 5.8166 0.9977 221125_WJC_METTL3_EV_vs_WT_F04.19218.19218.3 0.0401 Nov-52 K.VLEQLTGQTPVFSK[136.11].A "sp|P62913|RL11_HUMAN,tr|Q5VVC8|Q5VVC8_HUMAN" 2 1553.8545 3.37 52594 19218 3 1553.853826 518.9588 60S ribosomal protein L11 OS=Homo sapiens OX=9606 GN=RPL11 PE=1 SV=2 5.97 3201.2 - 723148 - - - -0.4074 - 1.736 0.244 - 119.2 1 2 0 -0.0006 14 0 0 0 1.81E+07 5.37E+06 - - - 2.726 0.9996 221125_WJC_METTL3_EV_vs_WT_F04.19220.19220.4 3.99E-05 14/108 K.LQEEMLQREEAENTLQSFR.Q "sp|P08670|VIME_HUMAN,tr|B0YJC5|B0YJC5_HUMAN,tr|B0YJC4|B0YJC4_HUMAN" 3 2350.1223 1.51 52596 19220 4 2350.12503 588.5379 Vimentin OS=Homo sapiens OX=9606 GN=VIM PE=1 SV=4 4.33 3201.4 - 577560 - - - 1.1514 - 2.189 0.423 - 102 1 2 1 0.0027 19 0 0 0 3.15E+06 2.09E+06 - - - 3.1721 0.9996 221125_WJC_METTL3_EV_vs_WT_F04.19221.19221.3 0.00116 14/48 K.QMELEQAVEHIAK[136.11].L sp|Q96T58|MINT_HUMAN 1 1532.7748 1.26 52597 19221 3 1532.774584 511.9322 Msx2-interacting protein OS=Homo sapiens OX=9606 GN=SPEN PE=1 SV=1 4.75 3201.6 - 577392 - - - -0.1592 - 1.831 0.336 - 196.2 1 2 0 -0.0002 13 0 0 0 1.22E+07 9.69E+06 - - - 3.926 0.9998 221125_WJC_METTL3_EV_vs_WT_F04.19223.19223.2 1.69E-06 28-Nov K.ESVDGQWVC[160.03]ISDVNK.G sp|P55735|SEC13_HUMAN 1 1734.7883 1.98 52599 19223 2 1734.785251 868.4014 Protein SEC13 homolog OS=Homo sapiens OX=9606 GN=SEC13 PE=1 SV=3 4.03 3201.8 - 351597 - - - -1.7576 - 2.439 0.598 - 393.2 1 2 0 -0.003 15 0 0 0 3.37E+06 1.70E+06 - - - 5.6489 1 221125_WJC_METTL3_EV_vs_WT_F04.19224.19224.2 5.79E-11 16/36 R.VADGLPLAASMQEDEQSGR[166.11].D sp|O75396|SC22B_HUMAN 1 1982.9243 2.08 52600 19224 2 1982.918394 992.4694 Vesicle-trafficking protein SEC22b OS=Homo sapiens OX=9606 GN=SEC22B PE=1 SV=5 3.92 3202 - 273836 - - - -2.9729 - 3.145 0.707 - 524.7 1 2 0 -0.0059 19 0 0 0 8.13E+06 3.90E+06 - - - 7.0781 0.9999 221125_WJC_METTL3_EV_vs_WT_F04.19226.19226.3 4.41E-07 13/60 R.AKFEEYGPVIEC[160.03]DIVK.D "sp|Q9BWF3|RBM4_HUMAN,sp|Q9BQ04|RBM4B_HUMAN,tr|E9PM61|E9PM61_HUMAN,tr|D6R9K7|D6R9K7_HUMAN,tr|J3QRR5|J3QRR5_HUMAN,tr|E9PB51|E9PB51_HUMAN,tr|U3KQD5|U3KQD5_HUMAN,tr|E9PLB0|E9PLB0_HUMAN" 8 1895.9339 1.62 52601 19226 3 1895.933294 632.9852 RNA-binding protein 4 OS=Homo sapiens OX=9606 GN=RBM4 PE=1 SV=1 4.41 3202.2 - 1.34E+07 - - - -0.3207 - 2.687 0.572 - 228.2 1 2 1 -0.0006 16 0 0 0 3.35E+08 2.07E+08 - - - 7.4532 1 221125_WJC_METTL3_EV_vs_WT_F04.19227.19227.2 0.00948 15/26 F.NQGLDC[160.03]DVIVAEVR[166.11].S sp|Q86U44|MTA70_HUMAN 1 1596.7805 0.05 52602 19227 2 1596.781054 799.3975 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 4.03 3202.2 - 3.96E+06 - - - 0.3307 - 3.367 0.609 - 963.7 1 1 0 0.0005 14 0 0 0 2.35E+06 4.94E+07 - - - 6.5854 1 221125_WJC_METTL3_EV_vs_WT_F04.19228.19228.3 3.13E-06 14/64 R.IINEPTAAAIAYGLDKK.G "sp|P54652|HSP72_HUMAN,sp|P11142|HSP7C_HUMAN,tr|E9PKE3|E9PKE3_HUMAN,tr|E9PN89|E9PN89_HUMAN,tr|E9PI65|E9PI65_HUMAN" 5 1786.9829 0.19 52603 19228 3 1786.98299 596.6682 Heat shock-related 70 kDa protein 2 OS=Homo sapiens OX=9606 GN=HSPA2 PE=1 SV=1 6.07 3202.3 - 3.34E+06 - - - 0.0504 - 2.791 0.486 - 157.7 1 2 0 0.0001 17 0 0 0 7.56E+07 4.02E+08 - - - 6.5514 1 221125_WJC_METTL3_EV_vs_WT_F04.19230.19230.3 3.74E-08 16/68 K.TVLQR[166.11]PLSLIQGPPGTGK[136.11].T sp|Q92900|RENT1_HUMAN 1 1879.101 1.06 52605 19230 3 1879.100847 627.3743 Regulator of nonsense transcripts 1 OS=Homo sapiens OX=9606 GN=UPF1 PE=1 SV=2 11 3202.4 - 1.93E+06 - - - -0.0825 - 3.043 0.582 - 246 1 2 0 -0.0002 18 0 0 0 4.52E+07 4.26E+07 - - - 7.7998 1 221125_WJC_METTL3_EV_vs_WT_F04.19231.19231.3 1.37E-05 23/68 K.TVLQRPLSLIQGPPGTGK.T sp|Q92900|RENT1_HUMAN 1 1861.0785 1.03 52606 19231 3 1861.078244 621.3668 Regulator of nonsense transcripts 1 OS=Homo sapiens OX=9606 GN=UPF1 PE=1 SV=2 11 3202.5 - 1.31E+06 - - - -0.1547 - 3.801 0.565 - 492.9 1 2 0 -0.0003 18 0 0 0 4.39E+07 4.26E+07 - - - 8.1641 1 221125_WJC_METTL3_EV_vs_WT_F04.19232.19232.3 9.92E-08 21/64 K.FKDDVMPATYC[160.03]EIDLDK.E "sp|Q9HD45|TM9S3_HUMAN,tr|Q5TB53|Q5TB53_HUMAN" 2 2058.9278 1.01 52607 19232 3 2058.933092 687.3166 Transmembrane 9 superfamily member 3 OS=Homo sapiens OX=9606 GN=TM9SF3 PE=1 SV=2 4.04 3202.6 - 1.17E+06 - - - 2.5557 - 3.747 0.603 - 834 1 2 1 0.0053 17 0 0 0 2.27E+07 2.26E+07 - - - 8.5985 1 221125_WJC_METTL3_EV_vs_WT_F04.19233.19233.3 1.63E-06 15/68 R.TVVSGLVNHVPLEQMQNR[166.11].M "sp|Q12904|AIMP1_HUMAN,tr|A0A804HJ47|A0A804HJ47_HUMAN,tr|A0A5F9ZHC5|A0A5F9ZHC5_HUMAN" 3 2030.0607 1.64 52608 19233 3 2030.062539 677.6942 Aminoacyl tRNA synthase complex-interacting multifunctional protein 1 OS=Homo sapiens OX=9606 GN=AIMP1 PE=1 SV=2 6.41 3202.8 - 1.00E+06 - - - 0.9236 - 2.667 0.513 - 136.6 1 2 0 0.0019 18 0 0 0 4.36E+07 2.66E+07 - - - 6.7016 0.9999 221125_WJC_METTL3_EV_vs_WT_F04.19235.19235.3 5.21E-05 Dec-52 K.VLEQLTGQTPVFSK.A "sp|P62913|RL11_HUMAN,tr|Q5VVC8|Q5VVC8_HUMAN" 2 1545.8403 7.08 52610 19235 3 1545.841076 516.2874 60S ribosomal protein L11 OS=Homo sapiens OX=9606 GN=RPL11 PE=1 SV=2 5.97 3203 - 789500 - - - 0.5285 - 2.027 0.415 - 223.9 1 2 0 0.0008 14 0 0 0 3.80E+07 5.37E+06 - - - 5.0443 1 221125_WJC_METTL3_EV_vs_WT_F04.19236.19236.3 4.02E-07 17/72 R.VADGLPLAASMQEDEQSGR[166.11].D sp|O75396|SC22B_HUMAN 1 1982.9243 2.36 52611 19236 3 1982.922771 661.982 Vesicle-trafficking protein SEC22b OS=Homo sapiens OX=9606 GN=SEC22B PE=1 SV=5 3.92 3203.1 - 582162 - - - -0.7655 - 3.73 0.565 - 472.2 1 2 0 -0.0015 19 0 0 0 1.17E+07 4.97E+06 - - - 8.0729 0.9992 221125_WJC_METTL3_EV_vs_WT_F04.19237.19237.2 0.000211 14/26 R.LSQELEYLTEDVKR.L sp|P12270|TPR_HUMAN 1 1721.8836 19.78 52612 19237 2 1721.889833 861.9491 Nucleoprotein TPR OS=Homo sapiens OX=9606 GN=TPR PE=1 SV=3 4.41 3203.2 - 464049 - - - 3.6315 - 2.759 0.483 - 648 1 2 0 0.0063 14 0 0 0 3.44E+06 1.74E+05 - - - 5.1532 0.9855 221125_WJC_METTL3_EV_vs_WT_F04.19238.19238.2 0.00043 26-Oct K.IAILTC[160.03]PFEPPK[136.11]PK[136.11].T "sp|P48643|TCPE_HUMAN,tr|E9PCA1|E9PCA1_HUMAN,tr|B7ZAR1|B7ZAR1_HUMAN,tr|E7ENZ3|E7ENZ3_HUMAN" 4 1625.9186 0.4 52613 19238 2 1625.908813 813.9666 T-complex protein 1 subunit epsilon OS=Homo sapiens OX=9606 GN=CCT5 PE=1 SV=1 8.2 3203.4 - 447160 - - - -6.0108 - 1.983 0.348 - 178.7 1 2 0 -0.0098 14 0 0 0 3.15E+06 7.96E+06 - - - 3.3263 0.9971 221125_WJC_METTL3_EV_vs_WT_F04.19240.19240.3 5.50E-05 Aug-60 K.TFAVDETSVSGYIYHK.L sp|Q92900|RENT1_HUMAN 1 1815.8679 0.8 52614 19240 3 1815.878781 606.2966 Regulator of nonsense transcripts 1 OS=Homo sapiens OX=9606 GN=UPF1 PE=1 SV=2 5.29 3203.6 - 4.87E+06 - - - 5.9757 - 1.675 0.486 - 48.9 1 2 0 0.0109 16 0 0 0 3.73E+07 4.64E+07 - - - 5.2789 1 221125_WJC_METTL3_EV_vs_WT_F04.19242.19242.3 5.65E-06 15/56 K.KGEISELLVGSPSIR.A "sp|Q9NW68|BSDC1_HUMAN,tr|E9PQA7|E9PQA7_HUMAN,tr|E9PS77|E9PS77_HUMAN" 3 1583.8883 0.6 52615 19242 3 1583.889372 528.97 BSD domain-containing protein 1 OS=Homo sapiens OX=9606 GN=BSDC1 PE=1 SV=1 6.14 3203.8 - 1.35E+06 - - - 0.6945 - 2.899 0.491 - 278.5 1 2 0 0.0011 15 0 0 0 3.17E+07 5.24E+07 - - - 6.7912 1 221125_WJC_METTL3_EV_vs_WT_F04.19246.19246.3 2.50E-06 Dec-52 R.STYNHLSSWLTDAR.N "sp|P61106|RAB14_HUMAN,tr|X6RFL8|X6RFL8_HUMAN" 2 1649.7798 1.13 52619 19246 3 1649.780006 550.9339 Ras-related protein Rab-14 OS=Homo sapiens OX=9606 GN=RAB14 PE=1 SV=4 6.46 3204.1 - 1.10E+06 - - - 0.1346 - 2.607 0.552 - 186.3 1 2 0 0.0002 14 0 0 0 2.40E+07 2.12E+07 - - - 7.2406 1 221125_WJC_METTL3_EV_vs_WT_F04.19248.19248.3 1.47E-08 13/52 R.STYNHLSSWLTDAR[166.11].N "sp|P61106|RAB14_HUMAN,tr|X6RFL8|X6RFL8_HUMAN" 2 1659.7881 1.15 52621 19248 3 1659.78669 554.27 Ras-related protein Rab-14 OS=Homo sapiens OX=9606 GN=RAB14 PE=1 SV=4 6.46 3204.3 - 1.03E+06 - - - -0.8218 - 2.815 0.572 - 207.6 1 2 0 -0.0014 14 0 0 0 2.40E+07 2.09E+07 - - - 7.6673 0.9999 221125_WJC_METTL3_EV_vs_WT_F04.19250.19250.2 2.34E-07 14/32 R.EGNVPNIIIAGPPGTGK[136.11].T sp|P35250|RFC2_HUMAN 1 1640.8977 0.99 52623 19250 2 1640.898249 821.4561 Replication factor C subunit 2 OS=Homo sapiens OX=9606 GN=RFC2 PE=1 SV=3 6.1 3204.6 - 928851 - - - 0.3218 - 2.614 0.527 - 547.1 1 2 0 0.0005 17 0 0 0 1.08E+07 1.10E+07 - - - 5.2956 0.9999 221125_WJC_METTL3_EV_vs_WT_F04.19251.19251.3 8.36E-06 18/72 R.EDLMGLAIGTHGSNIQQAR.K "sp|P51114|FXR1_HUMAN,tr|E7EU85|E7EU85_HUMAN,tr|E9PFF5|E9PFF5_HUMAN,tr|B4DXZ6|B4DXZ6_HUMAN" 4 2009.9953 86.07 52624 19251 3 2009.990404 671.0057 Fragile X mental retardation syndrome-related protein 1 OS=Homo sapiens OX=9606 GN=FXR1 PE=1 SV=3 5.32 3204.7 - 777210 - - - -2.4224 - 3.239 0.494 - 382.3 1 2 0 -0.0049 19 0 0 0 9.54E+06 1.11E+05 - - - 6.9337 1 221125_WJC_METTL3_EV_vs_WT_F04.19253.19253.4 0.000198 19/108 K.ILGSGISSSSVLHGMVFK[136.11]K[136.11].E sp|P50990|TCPQ_HUMAN 1 1962.0943 0.23 52626 19253 4 1962.094895 491.5309 T-complex protein 1 subunit theta OS=Homo sapiens OX=9606 GN=CCT8 PE=1 SV=4 10 3204.9 - 614530 - - - 0.2936 - 3.015 0.47 - 244.5 1 2 0 0.0006 19 0 0 0 4.64E+06 1.99E+07 - - - 3.69 1 221125_WJC_METTL3_EV_vs_WT_F04.19259.19259.2 5.98E-08 13/28 R.ELAQQVQQVADDYGK.C "sp|Q92841|DDX17_HUMAN,tr|A0A5H1ZRQ2|A0A5H1ZRQ2_HUMAN,tr|A0A1X7SBZ2|A0A1X7SBZ2_HUMAN" 3 1690.8162 1.12 52630 19259 2 1690.815767 846.4154 Probable ATP-dependent RNA helicase DDX17 OS=Homo sapiens OX=9606 GN=DDX17 PE=1 SV=2 4.03 3205.7 - 1.82E+06 - - - -0.2732 - 2.774 0.585 - 728.6 1 2 0 -0.0005 15 0 0 0 1.25E+08 1.12E+08 - - - 5.8701 0.9999 221125_WJC_METTL3_EV_vs_WT_F04.19260.19260.2 8.52E-07 18/28 R.ELAQQVQQVADDYGK[136.11].C "sp|Q92841|DDX17_HUMAN,tr|A0A5H1ZRQ2|A0A5H1ZRQ2_HUMAN,tr|A0A1X7SBZ2|A0A1X7SBZ2_HUMAN" 3 1698.8304 1.12 52631 19260 2 1698.829184 850.4225 Probable ATP-dependent RNA helicase DDX17 OS=Homo sapiens OX=9606 GN=DDX17 PE=1 SV=2 4.03 3205.9 - 2.07E+06 - - - -0.7329 - 3.282 0.461 - 1440.7 1 2 0 -0.0012 15 0 0 0 1.25E+08 1.12E+08 - - - 5.3674 0.9999 221125_WJC_METTL3_EV_vs_WT_F04.19261.19261.3 7.51E-06 18/64 K.EAFSLFDKDGDGTITTK.E "sp|P0DP25|CALM3_HUMAN,sp|P0DP23|CALM1_HUMAN,sp|P0DP24|CALM2_HUMAN,tr|F8WBR5|F8WBR5_HUMAN,tr|G3V479|G3V479_HUMAN,tr|M0QZ52|M0QZ52_HUMAN,tr|E7EMB3|E7EMB3_HUMAN" 7 1843.884 1.12 52632 19261 3 1843.878955 615.6353 Calmodulin-3 OS=Homo sapiens OX=9606 GN=CALM3 PE=1 SV=1 4.23 3205.9 - 1.98E+06 - - - -2.722 - 3.168 0.61 - 340.3 1 2 1 -0.005 17 0 0 0 1.80E+08 1.60E+08 - - - 8.2526 1 221125_WJC_METTL3_EV_vs_WT_F04.19266.19266.2 7.95E-08 14/22 K.SFFDNISC[160.03]DDNR.E "sp|Q8ND56|LS14A_HUMAN,tr|A0A096LP11|A0A096LP11_HUMAN,tr|A0A140TA76|A0A140TA76_HUMAN,tr|A0A0G2JQ95|A0A0G2JQ95_HUMAN" 4 1488.594 1.01 52637 19266 2 1488.594462 745.3043 Protein LSM14 homolog A OS=Homo sapiens OX=9606 GN=LSM14A PE=1 SV=3 3.93 3206.5 - 924035 - - - 0.3392 - 2.173 0.685 - 682.4 1 2 0 0.0005 12 0 0 0 2.80E+09 2.78E+09 - - - 6.1423 0.9999 221125_WJC_METTL3_EV_vs_WT_F04.19267.19267.3 0.00122 13/64 R.SAVDQAGGAQIVIDHLR[166.11].S "sp|P52306|GDS1_HUMAN,tr|D6RHH8|D6RHH8_HUMAN,tr|D6REZ0|D6REZ0_HUMAN" 3 1758.9252 0.47 52638 19267 3 1758.92442 587.3157 Rap1 GTPase-GDP dissociation stimulator 1 OS=Homo sapiens OX=9606 GN=RAP1GDS1 PE=1 SV=3 5.19 3206.7 - 573480 - - - -0.4525 - 2.926 0.386 - 231.8 1 2 0 -0.0008 17 0 0 0 1.84E+06 3.90E+06 - - - 5.5556 1 221125_WJC_METTL3_EV_vs_WT_F04.19273.19273.3 5.46E-13 27/84 R.GPADSLSTAAGAAELSAEGAGK.S sp|Q7Z5L9|I2BP2_HUMAN 1 1929.928 1.27 52643 19273 3 1929.927722 644.3166 Interferon regulatory factor 2-binding protein 2 OS=Homo sapiens OX=9606 GN=IRF2BP2 PE=1 SV=2 4.14 3207.3 - 2.67E+06 - - - -0.1254 - 4.659 0.624 - 785.1 1 2 0 -0.0002 22 0 0 0 1.65E+08 1.30E+08 - - - 9.1452 1 221125_WJC_METTL3_EV_vs_WT_F04.19274.19274.2 2.30E-08 14/22 K.SFFDNISC[160.03]DDNR[166.11].E "sp|Q8ND56|LS14A_HUMAN,tr|A0A096LP11|A0A096LP11_HUMAN,tr|A0A140TA76|A0A140TA76_HUMAN,tr|A0A0G2JQ95|A0A0G2JQ95_HUMAN" 4 1498.6022 1.01 52644 19274 2 1498.600778 750.3084 Protein LSM14 homolog A OS=Homo sapiens OX=9606 GN=LSM14A PE=1 SV=3 3.93 3207.4 - 4.15E+06 - - - -0.9669 - 2.71 0.732 - 666 1 2 0 -0.0014 12 0 0 0 2.80E+09 2.78E+09 - - - 7.0702 0.9997 221125_WJC_METTL3_EV_vs_WT_F04.19277.19277.3 0.000914 Nov-44 K.GK[136.11]EFEFSQLPLK[136.11].V "sp|Q9Y5M8|SRPRB_HUMAN,tr|H7C4H2|H7C4H2_HUMAN" 2 1437.7839 1.24 52647 19277 3 1437.785181 480.2686 Signal recognition particle receptor subunit beta OS=Homo sapiens OX=9606 GN=SRPRB PE=1 SV=3 6.14 3207.7 - 745226 - - - 0.9139 - 2.248 0.451 - 137.1 1 2 1 0.0013 12 0 0 0 8.84E+06 7.11E+06 - - - 5.8132 1 221125_WJC_METTL3_EV_vs_WT_F04.19278.19278.2 9.75E-10 15/30 R.C[160.03]IPALDSLTPANEDQK[136.11].L "sp|P10809|CH60_HUMAN,tr|A0A7I2V2X6|A0A7I2V2X6_HUMAN,tr|A0A7I2YQK6|A0A7I2YQK6_HUMAN,tr|A0A7I2V599|A0A7I2V599_HUMAN" 4 1778.86 0.92 52648 19278 2 1778.852792 890.4373 "60 kDa heat shock protein, mitochondrial OS=Homo sapiens OX=9606 GN=HSPD1 PE=1 SV=2" 4.03 3207.8 - 654568 - - - -4.0605 - 2.51 0.661 - 422.5 1 2 0 -0.0072 16 0 0 0 6.87E+08 7.43E+08 - - - 6.1834 0.9996 221125_WJC_METTL3_EV_vs_WT_F04.19279.19279.3 0.00247 14/48 R.QLSEVFIQLPSR[166.11]K[136.11].E "sp|P51531|SMCA2_HUMAN,sp|P51532|SMCA4_HUMAN,tr|A0A2R8Y5K3|A0A2R8Y5K3_HUMAN,tr|B1ALF6|B1ALF6_HUMAN,tr|A0A2R8Y7S2|A0A2R8Y7S2_HUMAN,tr|A0A0U1RQX3|A0A0U1RQX3_HUMAN,tr|A0A0A0MSS5|A0A0A0MSS5_HUMAN,tr|A0A2R8Y7F3|A0A2R8Y7F3_HUMAN,tr|A0A2R8YGG3|A0A2R8YGG3_HUMAN,tr|A0A1W2PS06|A0A1W2PS06_HUMAN,tr|A0A2R8Y523|A0A2R8Y523_HUMAN,tr|A0A2R8Y6V2|A0A2R8Y6V2_HUMAN,tr|A0A0U1RRG6|A0A0U1RRG6_HUMAN,tr|Q9HBD4|Q9HBD4_HUMAN,tr|A0A0U1RRD6|A0A0U1RRD6_HUMAN,tr|K7EQF0|K7EQF0_HUMAN,tr|A0A0U1RR26|A0A0U1RR26_HUMAN,tr|F6T8Q0|F6T8Q0_HUMAN,tr|F6UH26|F6UH26_HUMAN,tr|A0A0U1RRF8|A0A0U1RRF8_HUMAN,tr|A0A0U1RR83|A0A0U1RR83_HUMAN,tr|B1ALG2|B1ALG2_HUMAN,tr|A0A2R8Y440|A0A2R8Y440_HUMAN,tr|A0A0U1RQU0|A0A0U1RQU0_HUMAN,tr|F6VDE0|F6VDE0_HUMAN,tr|A0A2R8YFK5|A0A2R8YFK5_HUMAN,tr|A0A0U1RRN2|A0A0U1RRN2_HUMAN,tr|A0A2R8Y7Y7|A0A2R8Y7Y7_HUMAN,tr|A0A2R8YF58|A0A2R8YF58_HUMAN,tr|A0A2R8Y526|A0A2R8Y526_HUMAN,tr|K7EP28|K7EP28_HUMAN,tr|A0A2R8YG32|A0A2R8YG32_HUMAN,tr|F6XE55|F6XE55_HUMAN,tr|B4DNT1|B4DNT1_HUMAN,tr|A0A2R8Y6N0|A0A2R8Y6N0_HUMAN,tr|A0A2R8YF80|A0A2R8YF80_HUMAN,tr|A0A0U1RRF5|A0A0U1RRF5_HUMAN,tr|A0A2R8Y4P4|A0A2R8Y4P4_HUMAN,tr|A0A0U1RQW7|A0A0U1RQW7_HUMAN,tr|A0A0U1RR09|A0A0U1RR09_HUMAN,tr|B1ALG1|B1ALG1_HUMAN" 41 1561.8947 0.9 52649 19279 3 1561.894716 521.6388 Probable global transcription activator SNF2L2 OS=Homo sapiens OX=9606 GN=SMARCA2 PE=1 SV=2 8.75 3208 - 477571 - - - 0.0115 - 1.775 0.351 - 163.2 1 2 0 0 13 0 0 0 4.89E+06 5.44E+06 - - - 4.009 0.9999 221125_WJC_METTL3_EV_vs_WT_F04.19284.19284.3 0.00152 15/56 K.K[136.11]GEISELLVGSPSIR[166.11].A "sp|Q9NW68|BSDC1_HUMAN,tr|E9PQA7|E9PQA7_HUMAN,tr|E9PS77|E9PS77_HUMAN" 3 1601.9107 0.66 52652 19284 3 1601.911056 534.9775 BSD domain-containing protein 1 OS=Homo sapiens OX=9606 GN=BSDC1 PE=1 SV=1 6.14 3208.6 - 1.44E+06 - - - 0.196 - 2.982 0.372 - 314.2 1 2 0 0.0003 15 0 0 0 3.43E+07 5.22E+07 - - - 5.5383 1 221125_WJC_METTL3_EV_vs_WT_F04.19285.19285.3 7.31E-12 23/80 R.LAQAHPAGPPTLDPVNDLQLK.D "sp|Q15477|SKIV2_HUMAN,tr|H7C5N0|H7C5N0_HUMAN" 2 2194.1746 1.46 52653 19285 3 2194.175449 732.3988 Helicase SKI2W OS=Homo sapiens OX=9606 GN=SKIV2L PE=1 SV=3 5.21 3208.7 - 1.08E+06 - - - 0.3792 - 4.732 0.597 - 728.9 1 2 0 0.0008 21 0 0 0 2.28E+07 1.57E+07 - - - 8.9222 1 221125_WJC_METTL3_EV_vs_WT_F04.19286.19286.3 1.71E-08 14/44 K.SFFDNISC[160.03]DDNR.E "sp|Q8ND56|LS14A_HUMAN,tr|A0A096LP11|A0A096LP11_HUMAN,tr|A0A140TA76|A0A140TA76_HUMAN,tr|A0A0G2JQ95|A0A0G2JQ95_HUMAN" 4 1488.594 1.05 52654 19286 3 1488.59086 497.2053 Protein LSM14 homolog A OS=Homo sapiens OX=9606 GN=LSM14A PE=1 SV=3 3.93 3208.8 - 944074 - - - -2.0805 - 2.326 0.675 - 303.5 1 2 0 -0.0031 12 0 0 0 2.01E+08 1.91E+08 - - - 8.4046 0.9893 221125_WJC_METTL3_EV_vs_WT_F04.19287.19287.3 0.00615 17/76 K.LGGIPDALPTVAAPR[166.11]PVC[160.03]QR[166.11].C sp|Q9BRP1|PDD2L_HUMAN 1 2107.1475 0.74 52655 19287 3 2107.157593 703.3898 Programmed cell death protein 2-like OS=Homo sapiens OX=9606 GN=PDCD2L PE=1 SV=1 8.25 3208.9 - 699541 - - - 4.7809 - 2.008 0.294 - 230.8 1 2 0 0.0101 20 0 0 0 8.32E+06 1.13E+07 - - - 3.5063 0.9999 221125_WJC_METTL3_EV_vs_WT_F04.19294.19294.3 0.000499 13/56 R.ELAQQVQQVADDYGK.C "sp|Q92841|DDX17_HUMAN,tr|A0A5H1ZRQ2|A0A5H1ZRQ2_HUMAN,tr|A0A1X7SBZ2|A0A1X7SBZ2_HUMAN" 3 1690.8162 1.18 52660 19294 3 1690.816718 564.6127 Probable ATP-dependent RNA helicase DDX17 OS=Homo sapiens OX=9606 GN=DDX17 PE=1 SV=2 4.03 3209.8 - 3.44E+06 - - - 0.2892 - 2.379 0.361 - 258.6 1 2 0 0.0005 15 0 0 0 4.53E+07 3.84E+07 - - - 4.8261 0.9999 221125_WJC_METTL3_EV_vs_WT_F04.19295.19295.4 0.00043 18/96 K.FMQASEDLLKEHYVDLK.D "sp|P15531|NDKA_HUMAN,tr|Q32Q12|Q32Q12_HUMAN,tr|J3KPD9|J3KPD9_HUMAN,tr|E5RHP0|E5RHP0_HUMAN,tr|E7ERL0|E7ERL0_HUMAN" 5 2065.019 1.41 52661 19295 4 2065.020561 517.262 Nucleoside diphosphate kinase A OS=Homo sapiens OX=9606 GN=NME1 PE=1 SV=1 4.75 3209.8 - 3.81E+06 - - - 0.7424 - 3.37 0.561 - 152.1 1 2 1 0.0015 17 0 0 0 4.49E+07 3.18E+07 - - - 4.5303 1 221125_WJC_METTL3_EV_vs_WT_F04.19296.19296.2 1.44E-10 15/32 R.SVGDGETVEFDVVEGEK.G "sp|Q9Y2T7|YBOX2_HUMAN,sp|P67809|YBOX1_HUMAN,sp|P16989|YBOX3_HUMAN,tr|H0Y449|H0Y449_HUMAN,tr|A0A0D9SEI8|A0A0D9SEI8_HUMAN" 5 1794.816 1.06 52662 19296 2 1794.80508 898.4153 Y-box-binding protein 2 OS=Homo sapiens OX=9606 GN=YBX2 PE=1 SV=2 3.77 3209.8 - 3.20E+06 - - - -6.0586 - 3.053 0.67 - 579 1 2 0 -0.0109 17 0 0 0 2.80E+08 2.65E+08 - - - 6.7302 0.9999 221125_WJC_METTL3_EV_vs_WT_F04.19297.19297.4 1.39E-07 16/96 K.FMQASEDLLK[136.11]EHYVDLK[136.11].D "sp|P15531|NDKA_HUMAN,tr|Q32Q12|Q32Q12_HUMAN,tr|J3KPD9|J3KPD9_HUMAN,tr|E5RHP0|E5RHP0_HUMAN,tr|E7ERL0|E7ERL0_HUMAN" 5 2081.0474 1.41 52663 19297 4 2081.047251 521.2691 Nucleoside diphosphate kinase A OS=Homo sapiens OX=9606 GN=NME1 PE=1 SV=1 4.75 3209.9 - 3.16E+06 - - - -0.0851 - 2.742 0.51 - 126.8 1 2 1 -0.0002 17 0 0 0 4.49E+07 3.18E+07 - - - 4.0152 1 221125_WJC_METTL3_EV_vs_WT_F04.19298.19298.3 2.16E-06 13/44 K.SFFDNISC[160.03]DDNR[166.11].E "sp|Q8ND56|LS14A_HUMAN,tr|A0A096LP11|A0A096LP11_HUMAN,tr|A0A140TA76|A0A140TA76_HUMAN,tr|A0A0G2JQ95|A0A0G2JQ95_HUMAN" 4 1498.6022 1.05 52664 19298 3 1498.600854 500.5414 Protein LSM14 homolog A OS=Homo sapiens OX=9606 GN=LSM14A PE=1 SV=3 3.93 3209.9 - 2.71E+06 - - - -0.9162 - 1.996 0.639 - 263.4 1 2 0 -0.0014 12 0 0 0 2.01E+08 1.91E+08 - - - 7.5796 0.8433 221125_WJC_METTL3_EV_vs_WT_F04.19299.19299.3 2.34E-05 14/64 K.FMQASEDLLKEHYVDLK.D "sp|P15531|NDKA_HUMAN,tr|Q32Q12|Q32Q12_HUMAN,tr|J3KPD9|J3KPD9_HUMAN,tr|E5RHP0|E5RHP0_HUMAN,tr|E7ERL0|E7ERL0_HUMAN" 5 2065.019 1.38 52665 19299 3 2065.010707 689.347 Nucleoside diphosphate kinase A OS=Homo sapiens OX=9606 GN=NME1 PE=1 SV=1 4.75 3210 - 2.11E+06 - - - -4.0295 - 2.494 0.124 - 182.1 1 2 1 -0.0083 17 0 0 0 1.86E+07 1.35E+07 - - - 2.2289 1 221125_WJC_METTL3_EV_vs_WT_F04.19301.19301.2 2.47E-09 23/42 R.GPADSLSTAAGAAELSAEGAGK[136.11].S sp|Q7Z5L9|I2BP2_HUMAN 1 1937.9422 1.7 52667 19301 2 1937.942854 969.9784 Interferon regulatory factor 2-binding protein 2 OS=Homo sapiens OX=9606 GN=IRF2BP2 PE=1 SV=2 4.14 3210.2 - 1.65E+06 - - - 0.356 - 4.836 0.71 - 1695.2 1 2 0 0.0007 22 0 0 0 1.06E+08 6.24E+07 - - - 8.1597 1 221125_WJC_METTL3_EV_vs_WT_F04.19304.19304.2 4.74E-12 21/32 K.EAFSLFDK[136.11]DGDGTITTK[136.11].E "sp|P0DP25|CALM3_HUMAN,sp|P0DP23|CALM1_HUMAN,sp|P0DP24|CALM2_HUMAN,tr|F8WBR5|F8WBR5_HUMAN,tr|G3V479|G3V479_HUMAN,tr|M0QZ52|M0QZ52_HUMAN,tr|E7EMB3|E7EMB3_HUMAN" 7 1859.9124 1.38 52670 19304 2 1859.917331 930.9635 Calmodulin-3 OS=Homo sapiens OX=9606 GN=CALM3 PE=1 SV=1 4.23 3210.6 - 626526 - - - 2.6652 - 4.042 0.644 - 1535.6 1 2 1 0.005 17 0 0 0 1.11E+07 8.03E+06 - - - 7.23 1 221125_WJC_METTL3_EV_vs_WT_F04.19305.19305.2 1.52E-09 19/32 K.EAFSLFDKDGDGTITTK.E "sp|P0DP25|CALM3_HUMAN,sp|P0DP23|CALM1_HUMAN,sp|P0DP24|CALM2_HUMAN,tr|F8WBR5|F8WBR5_HUMAN,tr|G3V479|G3V479_HUMAN,tr|M0QZ52|M0QZ52_HUMAN,tr|E7EMB3|E7EMB3_HUMAN" 7 1843.884 1.38 52671 19305 2 1843.87939 922.9493 Calmodulin-3 OS=Homo sapiens OX=9606 GN=CALM3 PE=1 SV=1 4.23 3210.7 - 584775 - - - -2.4861 - 3.823 0.679 - 1359.2 1 2 1 -0.0046 17 0 0 0 1.11E+07 8.03E+06 - - - 7.3517 1 221125_WJC_METTL3_EV_vs_WT_F04.19308.19308.3 6.77E-12 27/80 R.LAQAHPAGPPTLDPVNDLQLK[136.11].D "sp|Q15477|SKIV2_HUMAN,tr|H7C5N0|H7C5N0_HUMAN" 2 2202.1888 1.46 52673 19308 3 2202.18775 735.0702 Helicase SKI2W OS=Homo sapiens OX=9606 GN=SKIV2L PE=1 SV=3 5.21 3211.2 - 1.81E+06 - - - -0.4845 - 5.076 0.657 - 975.5 1 2 0 -0.0011 21 0 0 0 2.28E+07 1.57E+07 - - - 9.7593 1 221125_WJC_METTL3_EV_vs_WT_F04.19310.19310.2 5.66E-13 18/32 R.SVGDGETVEFDVVEGEK[136.11].G "sp|Q9Y2T7|YBOX2_HUMAN,sp|P67809|YBOX1_HUMAN,sp|P16989|YBOX3_HUMAN,tr|H0Y449|H0Y449_HUMAN,tr|A0A0D9SEI8|A0A0D9SEI8_HUMAN" 5 1802.8302 1.06 52674 19310 2 1802.828733 902.4224 Y-box-binding protein 2 OS=Homo sapiens OX=9606 GN=YBX2 PE=1 SV=2 3.77 3211.4 - 7.45E+06 - - - -0.7882 - 3.559 0.711 - 731.8 1 2 0 -0.0014 17 0 0 0 2.80E+08 2.65E+08 - - - 7.4131 0.9999 221125_WJC_METTL3_EV_vs_WT_F04.19312.19312.3 0.000293 15/64 K.FVINYDYPNSSEDYIHR[166.11].L "sp|P17844|DDX5_HUMAN,tr|J3KTA4|J3KTA4_HUMAN,tr|A0A0G2JLI4|A0A0G2JLI4_HUMAN" 3 2140.973 1.95 52676 19312 3 2140.971661 714.6649 Probable ATP-dependent RNA helicase DDX5 OS=Homo sapiens OX=9606 GN=DDX5 PE=1 SV=1 4.54 3211.5 - 4.52E+06 - - - -0.6039 - 2.706 0.423 - 254.7 1 2 0 -0.0013 17 0 0 0 8.77E+08 4.50E+08 - - - 5.7705 1 221125_WJC_METTL3_EV_vs_WT_F04.19313.19313.2 6.79E-11 16/34 K.QITSYGETC[160.03]PGLEQYAIK[136.11].K sp|P50990|TCPQ_HUMAN 1 2064.9918 0.29 52677 19313 2 2064.994609 1033.5032 T-complex protein 1 subunit theta OS=Homo sapiens OX=9606 GN=CCT8 PE=1 SV=4 4.53 3211.6 - 900200 - - - 1.3811 - 3.057 0.654 - 584.7 1 2 0 0.0029 18 0 0 0 3.83E+06 1.32E+07 - - - 6.6178 0.9995 221125_WJC_METTL3_EV_vs_WT_F04.19315.19315.3 0.00028 Nov-44 K.GKEFEFSQLPLK.V "sp|Q9Y5M8|SRPRB_HUMAN,tr|H7C4H2|H7C4H2_HUMAN" 2 1421.7555 1.22 52679 19315 3 1421.754891 474.9258 Signal recognition particle receptor subunit beta OS=Homo sapiens OX=9606 GN=SRPRB PE=1 SV=3 6.14 3211.9 - 715611 - - - -0.4051 - 1.797 0.437 - 125.9 1 2 1 -0.0006 12 0 0 0 8.84E+06 7.24E+06 - - - 5.0366 0.9999 221125_WJC_METTL3_EV_vs_WT_F04.19322.19322.3 1.99E-07 14/64 R.GAPPSSNIEDFHGLLPK[136.11].G "sp|P43243|MATR3_HUMAN,tr|A8MXP9|A8MXP9_HUMAN,tr|D6R991|D6R991_HUMAN,tr|A0A0R4J2E8|A0A0R4J2E8_HUMAN,tr|H0Y8T4|H0Y8T4_HUMAN,tr|D6REM6|D6REM6_HUMAN" 6 1785.9141 1.45 52684 19322 3 1785.909541 596.312 Matrin-3 OS=Homo sapiens OX=9606 GN=MATR3 PE=1 SV=2 5.32 3212.7 - 2.33E+06 - - - -2.5522 - 2.596 0.528 - 213.1 1 2 0 -0.0046 17 0 0 0 7.52E+09 5.17E+09 - - - 6.8354 0.9927 221125_WJC_METTL3_EV_vs_WT_F04.19324.19324.2 4.80E-06 Oct-44 K.LVQDVANNTNEEAGDGTTTATVL.A "sp|P10809|CH60_HUMAN,tr|C9JL25|C9JL25_HUMAN,tr|A0A7I2V2X6|A0A7I2V2X6_HUMAN,tr|A0A7I2YQK6|A0A7I2YQK6_HUMAN,tr|A0A7I2V599|A0A7I2V599_HUMAN,tr|E7EXB4|E7EXB4_HUMAN,tr|A0A7I2YQ71|A0A7I2YQ71_HUMAN,tr|E7ESH4|E7ESH4_HUMAN,tr|A0A7I2V5M1|A0A7I2V5M1_HUMAN,tr|A0A7I2V5K3|A0A7I2V5K3_HUMAN,tr|A0A7I2V369|A0A7I2V369_HUMAN" 11 2332.103 - 52686 19324 2 2332.101527 1167.0588 "60 kDa heat shock protein, mitochondrial OS=Homo sapiens OX=9606 GN=HSPD1 PE=1 SV=2" 3.43 3212.9 - 1.63E+06 - - - -0.6436 - 2.378 0.511 - 162.6 1 1 0 -0.0015 23 0 0 0 - - - - - 4.9445 0.9985 221125_WJC_METTL3_EV_vs_WT_F04.19325.19325.2 0.00067 24-Dec K.SDNKDDDIDIDAI.- sp|P55010|IF5_HUMAN 1 1447.6314 1.05 52687 19325 2 1447.631969 724.823 Eukaryotic translation initiation factor 5 OS=Homo sapiens OX=9606 GN=EIF5 PE=1 SV=2 3.57 3213.1 - 1.40E+06 - - - 0.3599 - 2.329 0.478 - 454.8 1 2 1 0.0005 13 0 0 0 1.52E+07 1.44E+07 - - - 4.7412 0.9993 221125_WJC_METTL3_EV_vs_WT_F04.19328.19328.3 0.00108 Dec-44 R.NMQDLVEDLKNK.Y "sp|P48668|K2C6C_HUMAN,sp|P04259|K2C6B_HUMAN" 2 1445.7184 999 52690 19328 3 1445.715972 482.9134 "Keratin, type II cytoskeletal 6C OS=Homo sapiens OX=9606 GN=KRT6C PE=1 SV=3" 4.56 3213.4 - 575947 - - - -1.6995 - 2.185 0.4 - 201.1 1 2 1 -0.0025 12 0 0 0 4.95E+06 0.00E+00 - - - 5.1654 1 221125_WJC_METTL3_EV_vs_WT_F04.19334.19334.3 5.53E-07 18/64 K.FVINYDYPNSSEDYIHR.L "sp|P17844|DDX5_HUMAN,tr|J3KTA4|J3KTA4_HUMAN,tr|A0A0G2JLI4|A0A0G2JLI4_HUMAN" 3 2130.9647 2.42 52694 19334 3 2130.963741 711.3288 Probable ATP-dependent RNA helicase DDX5 OS=Homo sapiens OX=9606 GN=DDX5 PE=1 SV=1 4.54 3214.1 - 1.75E+07 - - - -0.4425 - 3.298 0.606 - 346.2 1 2 0 -0.0009 17 0 0 0 1.09E+09 4.50E+08 - - - 8.3107 1 221125_WJC_METTL3_EV_vs_WT_F04.19335.19335.3 2.24E-05 13/64 R.GAPPSSNIEDFHGLLPK.G "sp|P43243|MATR3_HUMAN,tr|A8MXP9|A8MXP9_HUMAN,tr|D6R991|D6R991_HUMAN,tr|A0A0R4J2E8|A0A0R4J2E8_HUMAN,tr|H0Y8T4|H0Y8T4_HUMAN,tr|D6REM6|D6REM6_HUMAN" 6 1777.8999 1.42 52695 19335 3 1777.902057 593.6406 Matrin-3 OS=Homo sapiens OX=9606 GN=MATR3 PE=1 SV=2 5.32 3214.1 - 6.12E+06 - - - 1.2138 - 2.489 0.532 - 159.7 1 2 0 0.0022 17 0 0 0 5.81E+09 4.08E+09 - - - 6.7744 1 221125_WJC_METTL3_EV_vs_WT_F04.19336.19336.2 1.59E-11 18/36 F.GGSSGGYGGLGGFGGGSFR.G "sp|P13645|K1C10_HUMAN,tr|A0A1B0GVI3|A0A1B0GVI3_HUMAN" 2 1632.7281 4.59 52696 19336 2 1632.726366 817.3713 "Keratin, type I cytoskeletal 10 OS=Homo sapiens OX=9606 GN=KRT10 PE=1 SV=6" 8.75 3214.2 - 3.56E+06 - - - -1.0516 - 3.686 0.723 - 773.9 1 1 0 -0.0017 19 0 0 0 4.41E+07 9.62E+06 - - - 7.5878 1 221125_WJC_METTL3_EV_vs_WT_F04.19338.19338.3 9.17E-11 21/76 K.VNNSSLIGLGYTQTLK[136.11]PGIK[136.11].L sp|P21796|VDAC1_HUMAN 1 2118.202 1.21 52698 19338 3 2118.203619 707.0746 Voltage-dependent anion-selective channel protein 1 OS=Homo sapiens OX=9606 GN=VDAC1 PE=1 SV=2 9.7 3214.4 - 2.19E+06 - - - 0.7856 - 3.686 0.675 - 533.2 1 2 0 0.0017 20 0 0 0 2.71E+08 2.23E+08 - - - 9.23 1 221125_WJC_METTL3_EV_vs_WT_F04.19339.19339.3 9.42E-07 13/64 R.SVGDGETVEFDVVEGEK[136.11].G "sp|Q9Y2T7|YBOX2_HUMAN,sp|P67809|YBOX1_HUMAN,sp|P16989|YBOX3_HUMAN,tr|H0Y449|H0Y449_HUMAN,tr|A0A0D9SEI8|A0A0D9SEI8_HUMAN" 5 1802.8302 1.03 52699 19339 3 1802.826951 601.9507 Y-box-binding protein 2 OS=Homo sapiens OX=9606 GN=YBX2 PE=1 SV=2 3.77 3214.4 - 1.98E+06 - - - -1.7767 - 2.384 0.532 - 195.5 1 2 0 -0.0032 17 0 0 0 2.21E+07 2.15E+07 - - - 6.6652 1 221125_WJC_METTL3_EV_vs_WT_F04.19340.19340.3 2.17E-12 24/76 K.VNNSSLIGLGYTQTLKPGIK.L sp|P21796|VDAC1_HUMAN 1 2102.1736 1.19 52700 19340 3 2102.174466 701.7318 Voltage-dependent anion-selective channel protein 1 OS=Homo sapiens OX=9606 GN=VDAC1 PE=1 SV=2 9.7 3214.5 - 1.82E+06 - - - 0.4334 - 4.287 0.685 - 678.1 1 2 0 0.0009 20 0 0 0 2.85E+08 2.39E+08 - - - 9.7081 1 221125_WJC_METTL3_EV_vs_WT_F04.19342.19342.2 1.01E-08 16/32 K.TDPSSLGATSASFNFGK.K sp|Q9UKX7|NUP50_HUMAN 1 1685.7897 1.87 52702 19342 2 1685.787602 843.9021 Nuclear pore complex protein Nup50 OS=Homo sapiens OX=9606 GN=NUP50 PE=1 SV=2 5.5 3214.7 - 782979 - - - -1.2327 - 3.511 0.617 - 711.8 1 2 0 -0.0021 17 0 0 0 1.11E+07 5.91E+06 - - - 6.6852 0.9982 221125_WJC_METTL3_EV_vs_WT_F04.19346.19346.3 0.00204 Oct-64 R.SVGDGETVEFDVVEGEK.G "sp|Q9Y2T7|YBOX2_HUMAN,sp|P67809|YBOX1_HUMAN,sp|P16989|YBOX3_HUMAN,tr|H0Y449|H0Y449_HUMAN,tr|A0A0D9SEI8|A0A0D9SEI8_HUMAN" 5 1794.816 1.06 52704 19346 3 1794.809923 599.2793 Y-box-binding protein 2 OS=Homo sapiens OX=9606 GN=YBX2 PE=1 SV=2 3.77 3215.2 - 2.17E+06 - - - -3.3602 - 1.846 0.355 - 121.6 1 2 0 -0.006 17 0 0 0 2.21E+07 2.08E+07 - - - 4.0449 0.9999 221125_WJC_METTL3_EV_vs_WT_F04.19347.19347.4 1.32E-07 17/84 R.GFVFITFKEEEPVKK.V "sp|Q99729|ROAA_HUMAN,tr|D6R9P3|D6R9P3_HUMAN,tr|D6RD18|D6RD18_HUMAN,tr|D6RBZ0|D6RBZ0_HUMAN" 4 1796.9713 1.39 52705 19347 4 1796.969805 450.2501 Heterogeneous nuclear ribonucleoprotein A\B OS=Homo sapiens OX=9606 GN=HNRNPAB PE=1 SV=2 6.23 3215.3 - 1.62E+06 - - - -0.8169 - 3.013 0.529 - 173.2 1 2 1 -0.0015 15 0 0 0 4.96E+07 3.56E+07 - - - 4.2247 1 221125_WJC_METTL3_EV_vs_WT_F04.19348.19348.2 1.19E-08 15/30 K.DAGEGGLSLAIEGPSK[136.11].A "sp|P21333|FLNA_HUMAN,tr|Q60FE5|Q60FE5_HUMAN" 2 1507.761 0.09 52706 19348 2 1508.755691 754.8878 Filamin-A OS=Homo sapiens OX=9606 GN=FLNA PE=1 SV=4 4.14 3215.4 - 1.32E+06 - - - 659.7458 - 2.763 0.627 - 733.6 1 2 0 0.9947 16 0 0 0 3.14E+06 3.41E+07 - - - 5.8583 0.9999 221125_WJC_METTL3_EV_vs_WT_F04.19349.19349.4 7.57E-08 17/84 R.GFVFITFK[136.11]EEEPVK[136.11]K[136.11].V "sp|Q99729|ROAA_HUMAN,tr|D6R9P3|D6R9P3_HUMAN,tr|D6RD18|D6RD18_HUMAN,tr|D6RBZ0|D6RBZ0_HUMAN" 4 1821.0139 1.39 52707 19349 4 1821.010993 456.2607 Heterogeneous nuclear ribonucleoprotein A\B OS=Homo sapiens OX=9606 GN=HNRNPAB PE=1 SV=2 6.23 3215.5 - 1.20E+06 - - - -1.5815 - 3.03 0.605 - 192.1 1 2 1 -0.0029 15 0 0 0 4.93E+07 3.55E+07 - - - 4.8878 0.9998 221125_WJC_METTL3_EV_vs_WT_F04.19350.19350.3 3.87E-05 14/52 R.QNISPDKIPWSALK.T "sp|Q14204|DYHC1_HUMAN,tr|A0A7P0T9C4|A0A7P0T9C4_HUMAN,tr|A0A2R8Y706|A0A2R8Y706_HUMAN,tr|A0A7P0TAW9|A0A7P0TAW9_HUMAN,tr|A0A7P0TA13|A0A7P0TA13_HUMAN,tr|A0A7P0T7V5|A0A7P0T7V5_HUMAN,tr|A0A7P0T9R4|A0A7P0T9R4_HUMAN,tr|A0A2R8Y5T0|A0A2R8Y5T0_HUMAN" 8 1595.8671 0.36 52708 19350 3 1595.867973 532.963 Cytoplasmic dynein 1 heavy chain 1 OS=Homo sapiens OX=9606 GN=DYNC1H1 PE=1 SV=5 8.59 3215.7 - 1.09E+06 - - - 0.5207 - 2.407 0.457 - 248.4 1 2 1 0.0008 14 0 0 0 1.68E+07 4.60E+07 - - - 5.9692 0.9999 221125_WJC_METTL3_EV_vs_WT_F04.19353.19353.2 1.26E-05 15/30 R.SIQETLGESGSLLPNK[136.11].L sp|Q96BP2|CHCH1_HUMAN 1 1679.8821 1.34 52711 19353 2 1679.882976 840.9483 Coiled-coil-helix-coiled-coil-helix domain-containing protein 1 OS=Homo sapiens OX=9606 GN=CHCHD1 PE=1 SV=1 4.53 3216.1 - 591652 - - - 0.5036 - 2.599 0.532 - 458.9 1 2 0 0.0008 16 0 0 0 8.95E+08 6.68E+08 - - - 5.3183 0.9999 221125_WJC_METTL3_EV_vs_WT_F04.19354.19354.4 1.86E-06 17/90 R.ASVLFDTMQHHLALNR.D sp|P46821|MAP1B_HUMAN 1 1851.9414 2.61 52712 19354 4 1851.942137 463.9926 Microtubule-associated protein 1B OS=Homo sapiens OX=9606 GN=MAP1B PE=1 SV=2 6.96 3216.2 - 552588 - - - 0.405 - 2.972 0.435 - 249.9 1 2 0 0.0008 16 0 0 0 7.36E+06 2.82E+06 - - - 3.3957 0.9995 221125_WJC_METTL3_EV_vs_WT_F04.19355.19355.2 8.49E-05 30-Dec K.NTVANSPQTLLAGMNK[136.11].F sp|P61221|ABCE1_HUMAN 1 1665.86 1.45 52713 19355 2 1665.855469 833.9373 ATP-binding cassette sub-family E member 1 OS=Homo sapiens OX=9606 GN=ABCE1 PE=1 SV=1 8.75 3216.3 - 0 - - - -2.6929 - 2.485 0.465 - 322.7 1 2 0 -0.0045 16 0 0 0 8.07E+06 5.58E+06 - - - 4.712 1 221125_WJC_METTL3_EV_vs_WT_F04.19359.19359.3 4.36E-10 19/44 R.RHPDYSVVLLLR.L "sp|P02768|ALBU_HUMAN,tr|B7WNR0|B7WNR0_HUMAN,tr|H0YA55|H0YA55_HUMAN,tr|A0A0C4DGB6|A0A0C4DGB6_HUMAN,tr|D6RHD5|D6RHD5_HUMAN,tr|C9JKR2|C9JKR2_HUMAN" 6 1466.8358 999 52715 19359 3 1466.833514 489.9525 Albumin OS=Homo sapiens OX=9606 GN=ALB PE=1 SV=2 8.75 3216.7 - 3.75E+06 - - - -1.5469 - 3.596 0.686 - 870.9 1 2 0 -0.0023 12 0 0 0 5.09E+07 0.00E+00 - - - 9.7351 0.9999 221125_WJC_METTL3_EV_vs_WT_F04.19360.19360.3 2.97E-07 16/60 K.IIVDELK[136.11]QEVISTSSK[136.11].A "sp|P63244|RACK1_HUMAN,tr|H0YAM7|H0YAM7_HUMAN,tr|H0YAF8|H0YAF8_HUMAN,tr|H0Y9P0|H0Y9P0_HUMAN,tr|D6RF23|D6RF23_HUMAN,tr|J3KPE3|J3KPE3_HUMAN,tr|D6RAC2|D6RAC2_HUMAN,tr|D6REE5|D6REE5_HUMAN,tr|H0Y8W2|H0Y8W2_HUMAN" 9 1804.0164 0.97 52716 19360 3 1804.014695 602.3461 Receptor of activated protein C kinase 1 OS=Homo sapiens OX=9606 GN=RACK1 PE=1 SV=3 4.68 3216.8 - 5.00E+06 - - - -0.9701 - 3.061 0.597 - 270.5 1 2 1 -0.0018 16 0 0 0 1.42E+08 1.46E+08 - - - 8.066 0.9991 221125_WJC_METTL3_EV_vs_WT_F04.19366.19366.3 0.00701 Nov-52 K.FKGPFTDVVTTNLK.L sp|Q9P0L0|VAPA_HUMAN 1 1565.8453 0.99 52722 19366 3 1565.842655 522.9557 Vesicle-associated membrane protein-associated protein A OS=Homo sapiens OX=9606 GN=VAPA PE=1 SV=3 8.59 3217.3 - 1.21E+06 - - - -1.7173 - 2.436 0.358 - 135.9 1 2 1 -0.0027 14 0 0 0 4.79E+07 4.83E+07 - - - 4.8968 0.9992 221125_WJC_METTL3_EV_vs_WT_F04.19367.19367.2 6.71E-05 15/30 R.SIQETLGESGSLLPNK.L sp|Q96BP2|CHCH1_HUMAN 1 1671.8679 1.34 52723 19367 2 1671.861364 836.9412 Coiled-coil-helix-coiled-coil-helix domain-containing protein 1 OS=Homo sapiens OX=9606 GN=CHCHD1 PE=1 SV=1 4.53 3217.4 - 1.13E+06 - - - -3.9273 - 2.968 0.512 - 412.7 1 2 0 -0.0066 16 0 0 0 8.95E+08 6.68E+08 - - - 5.4952 1 221125_WJC_METTL3_EV_vs_WT_F04.19368.19368.2 8.81E-12 20/34 R.VASVSQNAIVSAAGNIAR.T "sp|O75694|NU155_HUMAN,tr|E9PF10|E9PF10_HUMAN" 2 1726.9326 1.71 52724 19368 2 1726.931055 864.4736 Nuclear pore complex protein Nup155 OS=Homo sapiens OX=9606 GN=NUP155 PE=1 SV=1 9.72 3217.6 - 983237 - - - -0.8923 - 3.576 0.652 - 1186.9 1 2 0 -0.0015 18 0 0 0 3.14E+07 1.83E+07 - - - 6.989 1 221125_WJC_METTL3_EV_vs_WT_F04.19370.19370.3 1.42E-05 14/60 R.SIQETLGESGSLLPNK.L sp|Q96BP2|CHCH1_HUMAN 1 1671.8679 1.2 52726 19370 3 1671.865957 558.2966 Coiled-coil-helix-coiled-coil-helix domain-containing protein 1 OS=Homo sapiens OX=9606 GN=CHCHD1 PE=1 SV=1 4.53 3217.8 - 818818 - - - -1.1801 - 2.608 0.459 - 206 1 2 0 -0.002 16 0 0 0 4.22E+08 3.51E+08 - - - 6.1164 0.9973 221125_WJC_METTL3_EV_vs_WT_F04.19372.19372.3 0.00555 Dec-40 R.LKDLEALLNSK.E "sp|P02545|LMNA_HUMAN,tr|A0A6Q8PF80|A0A6Q8PF80_HUMAN,tr|A0A804HL68|A0A804HL68_HUMAN,tr|Q5TCI8|Q5TCI8_HUMAN,tr|A0A6Q8PFJ0|A0A6Q8PFJ0_HUMAN,tr|A0A6Q8PHQ9|A0A6Q8PHQ9_HUMAN,tr|A0A6Q8PGH0|A0A6Q8PGH0_HUMAN,tr|Q3BDU5|Q3BDU5_HUMAN" 8 1242.7184 3.1 52728 19372 3 1242.716848 415.2467 Prelamin-A\C OS=Homo sapiens OX=9606 GN=LMNA PE=1 SV=1 6.07 3218.1 - 684637 - - - -1.2111 - 2.51 0.234 - 181.1 1 2 1 -0.0015 11 0 0 0 1.26E+07 4.05E+06 - - - 3.7628 1 221125_WJC_METTL3_EV_vs_WT_F04.19376.19376.3 1.29E-08 17/72 K.YDPSLK[136.11]PLSVSYDQATSLR[166.11].L "sp|P00918|CAH2_HUMAN,tr|E5RID5|E5RID5_HUMAN,tr|E5RK37|E5RK37_HUMAN" 3 2157.1073 0.66 52730 19376 3 2157.107058 720.043 Carbonic anhydrase 2 OS=Homo sapiens OX=9606 GN=CA2 PE=1 SV=2 5.96 3218.6 - 1.32E+06 - - - -0.0978 - 3.365 0.615 - 405.8 1 2 0 -0.0002 19 0 0 0 1.25E+07 1.91E+07 - - - 8.3777 1 221125_WJC_METTL3_EV_vs_WT_F04.19377.19377.3 2.24E-08 15/56 R.QNLLSQSHAYQQFLR[166.11].D "sp|Q01082|SPTB2_HUMAN,tr|A0A087WUZ3|A0A087WUZ3_HUMAN" 2 1841.9412 0.87 52731 19377 3 1841.94407 614.9877 "Spectrin beta chain, non-erythrocytic 1 OS=Homo sapiens OX=9606 GN=SPTBN1 PE=1 SV=2" 8.75 3218.6 - 1.93E+06 - - - 1.5581 - 3.304 0.554 - 375.7 1 2 0 0.0029 15 0 0 0 2.53E+07 2.92E+07 - - - 7.8343 0.9997 221125_WJC_METTL3_EV_vs_WT_F04.19379.19379.3 1.97 15/68 R.VASVSQNAIVSAAGNIAR.T "sp|O75694|NU155_HUMAN,tr|E9PF10|E9PF10_HUMAN" 2 1726.9326 1.58 52733 19379 3 1726.927035 576.6515 Nuclear pore complex protein Nup155 OS=Homo sapiens OX=9606 GN=NUP155 PE=1 SV=1 9.72 3218.8 - 1.70E+06 - - - -3.2202 - 3.35 0.373 - 297.1 1 2 0 -0.0056 18 0 0 0 2.93E+07 1.85E+07 - - - 5.7075 1 221125_WJC_METTL3_EV_vs_WT_F04.19380.19380.2 3.63E-10 22/34 R.VASVSQNAIVSAAGNIAR[166.11].T "sp|O75694|NU155_HUMAN,tr|E9PF10|E9PF10_HUMAN" 2 1736.9409 1.71 52734 19380 2 1736.938172 869.4777 Nuclear pore complex protein Nup155 OS=Homo sapiens OX=9606 GN=NUP155 PE=1 SV=1 9.72 3219 - 1.40E+06 - - - -1.551 - 3.931 0.643 - 1613.4 1 2 0 -0.0027 18 0 0 0 3.14E+07 1.83E+07 - - - 7.1548 0.9994 221125_WJC_METTL3_EV_vs_WT_F04.19381.19381.3 0.00089 20/68 R.VASVSQNAIVSAAGNIAR[166.11].T "sp|O75694|NU155_HUMAN,tr|E9PF10|E9PF10_HUMAN" 2 1736.9409 1.57 52735 19381 3 1737.942775 579.9876 Nuclear pore complex protein Nup155 OS=Homo sapiens OX=9606 GN=NUP155 PE=1 SV=1 9.72 3219.1 - 1.13E+06 - - - 576.8239 - 3.841 0.466 - 600.7 1 2 0 1.0019 18 0 0 0 2.91E+07 1.85E+07 - - - 6.8089 0.9999 221125_WJC_METTL3_EV_vs_WT_F04.19386.19386.3 7.76E-06 15/56 R.GFVFITFKEEEPVKK.V "sp|Q99729|ROAA_HUMAN,tr|D6R9P3|D6R9P3_HUMAN,tr|D6RD18|D6RD18_HUMAN,tr|D6RBZ0|D6RBZ0_HUMAN" 4 1796.9713 1.33 52738 19386 3 1796.967764 599.9977 Heterogeneous nuclear ribonucleoprotein A\B OS=Homo sapiens OX=9606 GN=HNRNPAB PE=1 SV=2 6.23 3219.6 - 2.46E+06 - - - -1.9527 - 3.045 0.527 - 296.6 1 2 1 -0.0035 15 0 0 0 2.96E+07 2.23E+07 - - - 7.3201 1 221125_WJC_METTL3_EV_vs_WT_F04.19387.19387.3 1.14E-05 15/56 R.QNLLSQSHAYQQFLR.D "sp|Q01082|SPTB2_HUMAN,tr|A0A087WUZ3|A0A087WUZ3_HUMAN" 2 1831.9329 0.88 52739 19387 3 1831.934546 611.6516 "Spectrin beta chain, non-erythrocytic 1 OS=Homo sapiens OX=9606 GN=SPTBN1 PE=1 SV=2" 8.75 3219.6 - 2.28E+06 - - - 0.8821 - 2.543 0.508 - 268.6 1 2 0 0.0016 15 0 0 0 2.53E+07 2.88E+07 - - - 6.6387 1 221125_WJC_METTL3_EV_vs_WT_F04.19392.19392.3 9.28E-13 17/72 K.K[136.11]VQGGALEDSQLVAGVAFK[136.11].K sp|Q99832|TCPH_HUMAN 1 1932.0651 0.18 52743 19392 3 1932.063745 645.029 T-complex protein 1 subunit eta OS=Homo sapiens OX=9606 GN=CCT7 PE=1 SV=2 6.07 3220.1 - 8.87E+06 - - - -0.7153 - 3.542 0.578 - 456.2 1 2 0 -0.0014 19 0 0 0 2.14E+07 1.21E+08 - - - 8.0908 0.9678 221125_WJC_METTL3_EV_vs_WT_F04.19394.19394.2 0.00193 22-Aug K.NQILNLTTDNAN.L "sp|P13645|K1C10_HUMAN,tr|A0A1B0GVI3|A0A1B0GVI3_HUMAN" 2 1329.6525 - 52744 19394 2 1329.654407 665.8335 "Keratin, type I cytoskeletal 10 OS=Homo sapiens OX=9606 GN=KRT10 PE=1 SV=6" 3.8 3220.3 - 2.19E+06 - - - 1.4658 - 1.68 0.415 - 193.7 1 1 0 0.0019 12 0 0 0 - - - - - 3.4706 1 221125_WJC_METTL3_EV_vs_WT_F04.19395.19395.3 7.35E-07 15/52 K.DHTLEDEDVIQIVK[136.11].K sp|Q9Y295|DRG1_HUMAN 1 1660.8399 0.29 52745 19395 3 1660.836497 554.6206 Developmentally-regulated GTP-binding protein 1 OS=Homo sapiens OX=9606 GN=DRG1 PE=1 SV=1 4.1 3220.4 - 833369 - - - -2.0676 - 2.814 0.529 - 280.5 1 2 0 -0.0034 14 0 0 0 4.51E+06 1.55E+07 - - - 7.1864 1 221125_WJC_METTL3_EV_vs_WT_F04.19397.19397.3 5.78E-07 Dec-60 R.SIQETLGESGSLLPNK[136.11].L sp|Q96BP2|CHCH1_HUMAN 1 1679.8821 1.2 52747 19397 3 1679.880232 560.968 Coiled-coil-helix-coiled-coil-helix domain-containing protein 1 OS=Homo sapiens OX=9606 GN=CHCHD1 PE=1 SV=1 4.53 3220.5 - 1.62E+06 - - - -1.1298 - 2.471 0.557 - 122.9 1 2 0 -0.0019 16 0 0 0 4.22E+08 3.51E+08 - - - 7.0706 0.9999 221125_WJC_METTL3_EV_vs_WT_F04.19400.19400.3 4.40E-07 17/80 R.TFATYGYALDPSLDNHQVSAK[136.11].Y "sp|O60508|PRP17_HUMAN,tr|Q5SRN1|Q5SRN1_HUMAN" 2 2305.1106 0.97 52750 19400 3 2305.120286 769.3775 Pre-mRNA-processing factor 17 OS=Homo sapiens OX=9606 GN=CDC40 PE=1 SV=1 5.18 3220.9 - 1.79E+06 - - - 4.1903 - 3.077 0.574 - 167.8 1 2 0 0.0097 21 0 0 0 1.86E+07 1.91E+07 - - - 7.6315 0.9994 221125_WJC_METTL3_EV_vs_WT_F04.19401.19401.3 0.000122 13/44 R.TRLGLDDFESLK.V "sp|Q9Y2H1|ST38L_HUMAN,tr|F5GY51|F5GY51_HUMAN,tr|I3L0D0|I3L0D0_HUMAN,tr|F5H7Z3|F5H7Z3_HUMAN" 4 1392.7249 3.15 52751 19401 3 1392.726426 465.2489 Serine\threonine-protein kinase 38-like OS=Homo sapiens OX=9606 GN=STK38L PE=1 SV=3 4.56 3221 - 802812 - - - 1.0993 - 2.465 0.369 - 211.2 1 2 1 0.0015 12 0 0 0 7.02E+06 2.23E+06 - - - 5.1543 1 221125_WJC_METTL3_EV_vs_WT_F04.19402.19402.2 8.36E-11 15/38 K.VNNSSLIGLGYTQTLKPGIK.L sp|P21796|VDAC1_HUMAN 1 2102.1736 1.37 52752 19402 2 2102.176564 1052.0941 Voltage-dependent anion-selective channel protein 1 OS=Homo sapiens OX=9606 GN=VDAC1 PE=1 SV=2 9.7 3221.1 - 593686 - - - 1.4314 - 3.049 0.656 - 487.3 1 2 0 0.003 20 0 0 0 4.52E+06 3.31E+06 - - - 6.6261 0.9999 221125_WJC_METTL3_EV_vs_WT_F04.19404.19404.3 1.24E-07 17/68 R.IIAFVGSPVEDNEKDLVK.L "sp|P55036|PSMD4_HUMAN,tr|A6PVX3|A6PVX3_HUMAN,tr|Q5VWC4|Q5VWC4_HUMAN" 3 1972.0517 1.64 52754 19404 3 1972.050983 658.3578 26S proteasome non-ATPase regulatory subunit 4 OS=Homo sapiens OX=9606 GN=PSMD4 PE=1 SV=1 4.32 3221.4 - 480329 - - - -0.3676 - 3.021 0.548 - 250.3 1 2 1 -0.0007 18 0 0 0 5.22E+06 3.17E+06 - - - 7.4025 0.9998 221125_WJC_METTL3_EV_vs_WT_F04.19407.19407.3 7.15E-06 13/64 K.NMAILDPPDADHLYSAK.V "sp|Q8IX12|CCAR1_HUMAN,tr|F5H2E6|F5H2E6_HUMAN,tr|F5H1H2|F5H1H2_HUMAN,tr|A0A0C4DGG8|A0A0C4DGG8_HUMAN,tr|F5H3E1|F5H3E1_HUMAN" 5 1869.8931 4.81 52755 19407 3 1869.885765 624.305 Cell division cycle and apoptosis regulator protein 1 OS=Homo sapiens OX=9606 GN=CCAR1 PE=1 SV=2 4.41 3221.8 - 2.74E+06 - - - -3.9221 - 2.675 0.538 - 184.2 1 2 0 -0.0073 17 0 0 0 1.06E+08 2.20E+07 - - - 7.0219 1 221125_WJC_METTL3_EV_vs_WT_F04.19408.19408.2 1.31E-09 21/30 K.IIVDELK[136.11]QEVISTSSK[136.11].A "sp|P63244|RACK1_HUMAN,tr|H0YAM7|H0YAM7_HUMAN,tr|H0YAF8|H0YAF8_HUMAN,tr|H0Y9P0|H0Y9P0_HUMAN,tr|D6RF23|D6RF23_HUMAN,tr|J3KPE3|J3KPE3_HUMAN,tr|D6RAC2|D6RAC2_HUMAN,tr|D6REE5|D6REE5_HUMAN,tr|H0Y8W2|H0Y8W2_HUMAN" 9 1804.0164 0.91 52756 19408 2 1804.013983 903.0155 Receptor of activated protein C kinase 1 OS=Homo sapiens OX=9606 GN=RACK1 PE=1 SV=3 4.68 3221.9 - 1.91E+06 - - - -1.3647 - 4.059 0.676 - 1613 1 2 1 -0.0025 16 0 0 0 2.50E+07 2.75E+07 - - - 7.4774 1 221125_WJC_METTL3_EV_vs_WT_F04.19409.19409.2 1.95E-09 15/32 R.FSGVPDRFSGSGSGTDF.T "sp|A2NJV5|KV229_HUMAN,sp|A0A075B6S2|KVD29_HUMAN,sp|A0A0A0MRZ7|KVD26_HUMAN" 3 1718.7536 122 52757 19409 2 1718.751837 860.3841 Immunoglobulin kappa variable 2-29 OS=Homo sapiens OX=9606 GN=IGKV2-29 PE=3 SV=2 4.21 3222 - 2.12E+06 - - - -1.0426 - 2.88 0.576 - 421.3 1 1 1 -0.0018 17 0 0 0 3.16E+07 2.59E+05 - - - 5.8954 0.9999 221125_WJC_METTL3_EV_vs_WT_F04.19410.19410.2 4.84E-06 18-Nov R.GYFEYIEENK[136.11].Y "sp|Q00839|HNRPU_HUMAN,tr|Q5RI18|Q5RI18_HUMAN,tr|A0A1W2PP35|A0A1W2PP35_HUMAN,tr|A0A1W2PPS1|A0A1W2PPS1_HUMAN,tr|A0A1W2PRI6|A0A1W2PRI6_HUMAN" 5 1298.591 1.07 52758 19410 2 1298.590148 650.3028 Heterogeneous nuclear ribonucleoprotein U OS=Homo sapiens OX=9606 GN=HNRNPU PE=1 SV=6 4.25 3222.2 - 1.04E+06 - - - -0.6815 - 2.238 0.509 - 363.8 1 2 0 -0.0009 10 0 0 0 1.72E+07 1.60E+07 - - - 5.0488 1 221125_WJC_METTL3_EV_vs_WT_F04.19412.19412.2 9.20E-10 18/32 K.FVINYDYPNSSEDYIHR.L "sp|P17844|DDX5_HUMAN,tr|J3KTA4|J3KTA4_HUMAN,tr|A0A0G2JLI4|A0A0G2JLI4_HUMAN" 3 2130.9647 2.31 52760 19412 2 2130.965023 1066.4896 Probable ATP-dependent RNA helicase DDX5 OS=Homo sapiens OX=9606 GN=DDX5 PE=1 SV=1 4.54 3222.4 - 531137 - - - 0.1591 - 3.621 0.685 - 797.8 1 2 0 0.0003 17 0 0 0 1.56E+07 6.75E+06 - - - 7.2638 0.8285 221125_WJC_METTL3_EV_vs_WT_F04.19413.19413.3 0.221 Jun-44 R.SMGFIGHYLDQK[136.11].R sp|P53396|ACLY_HUMAN 1 1402.6795 0.57 52761 19413 3 1402.67922 468.5671 ATP-citrate synthase OS=Homo sapiens OX=9606 GN=ACLY PE=1 SV=3 6.46 3222.6 - 465219 - - - -0.1789 - 1.27 0.119 - 24 8 2 0 -0.0003 12 0 0 0 2.54E+06 4.43E+06 - - - 0.1112 1 221125_WJC_METTL3_EV_vs_WT_F04.19414.19414.2 1.99E-07 14/34 K.SAIVHLINYQDDAELATR.A "sp|P14923|PLAK_HUMAN,tr|C9JKY1|C9JKY1_HUMAN,tr|C9JK18|C9JK18_HUMAN,tr|C9JTX4|C9JTX4_HUMAN,tr|C9J826|C9J826_HUMAN" 5 2028.0276 5.53 52762 19414 2 2028.021178 1015.0211 Junction plakoglobin OS=Homo sapiens OX=9606 GN=JUP PE=1 SV=3 4.53 3222.7 - 460290 - - - -3.176 - 3.368 0.517 - 540.2 1 2 0 -0.0064 18 0 0 0 4.60E+06 8.31E+05 - - - 5.843 0.9985 221125_WJC_METTL3_EV_vs_WT_F04.19415.19415.3 0.0425 Nov-56 R.LLIHQSLAGGIIGVK.G "sp|P61978|HNRPK_HUMAN,tr|Q5T6W2|Q5T6W2_HUMAN" 2 1517.9293 0.98 52763 19415 3 1517.931291 506.9837 Heterogeneous nuclear ribonucleoprotein K OS=Homo sapiens OX=9606 GN=HNRNPK PE=1 SV=1 8.76 3222.8 - 449310 - - - 1.2794 - 1.919 0.265 - 115.3 1 2 0 0.0019 15 0 0 0 5.16E+06 5.25E+06 - - - 3.1947 0.8325 221125_WJC_METTL3_EV_vs_WT_F04.19416.19416.3 0.0801 Jul-56 R.LLIHQSLAGGIIGVK[136.11].G "sp|P61978|HNRPK_HUMAN,tr|Q5T6W2|Q5T6W2_HUMAN" 2 1525.9435 0.98 52764 19416 3 1525.945742 509.6551 Heterogeneous nuclear ribonucleoprotein K OS=Homo sapiens OX=9606 GN=HNRNPK PE=1 SV=1 8.76 3223 - 391472 - - - 1.4371 - 1.405 0.091 - 40.5 2 2 0 0.0022 15 0 0 0 5.16E+06 5.25E+06 - - - 0.3019 0.9968 221125_WJC_METTL3_EV_vs_WT_F04.19417.19417.3 0.0351 13/44 R.NKLAELEEALQK.A "sp|P13647|K2C5_HUMAN,tr|H0YI76|H0YI76_HUMAN" 2 1384.7562 129.73 52765 19417 3 1384.755576 462.5927 "Keratin, type II cytoskeletal 5 OS=Homo sapiens OX=9606 GN=KRT5 PE=1 SV=3" 4.79 3223.1 - 383753 - - - -0.447 - 2.268 0.248 - 348.4 1 2 1 -0.0006 12 0 0 0 1.33E+08 1.02E+06 - - - 3.5746 0.9999 221125_WJC_METTL3_EV_vs_WT_F04.19420.19420.2 1.24E-05 20-Oct R.DQTIVDPFSSK[136.11].H sp|Q9UQE7|SMC3_HUMAN 1 1243.6176 0.84 52766 19420 2 1243.616518 622.8161 Structural maintenance of chromosomes protein 3 OS=Homo sapiens OX=9606 GN=SMC3 PE=1 SV=2 4.21 3223.5 - 2.79E+06 - - - -0.8564 - 2.132 0.538 - 382.3 1 2 0 -0.0011 11 0 0 0 3.36E+07 3.98E+07 - - - 5.0624 1 221125_WJC_METTL3_EV_vs_WT_F04.19421.19421.3 3.34E-07 18/84 K.YTPVQQGPVGVNVTYGGDPIPK.S "sp|P21333|FLNA_HUMAN,tr|A0A7P0NMY4|A0A7P0NMY4_HUMAN,tr|Q60FE5|Q60FE5_HUMAN" 3 2285.1692 1.09 52767 19421 3 2285.168792 762.7303 Filamin-A OS=Homo sapiens OX=9606 GN=FLNA PE=1 SV=4 5.83 3223.6 - 1.70E+06 - - - -0.1777 - 3.081 0.56 - 247.1 1 2 0 -0.0004 22 0 0 0 2.81E+07 2.57E+07 - - - 7.4511 0.9999 221125_WJC_METTL3_EV_vs_WT_F04.19422.19422.2 0.00013 20-Nov R.DQTIVDPFSSK.H sp|Q9UQE7|SMC3_HUMAN 1 1235.6034 0.84 52768 19422 2 1235.601874 618.809 Structural maintenance of chromosomes protein 3 OS=Homo sapiens OX=9606 GN=SMC3 PE=1 SV=2 4.21 3223.7 - 2.30E+06 - - - -1.2213 - 2.294 0.524 - 488.3 1 2 0 -0.0015 11 0 0 0 3.36E+07 3.98E+07 - - - 5.1569 1 221125_WJC_METTL3_EV_vs_WT_F04.19423.19423.3 1.99E-09 21/52 K.K[136.11]ADVDAIHEYLLLK[136.11].G sp|Q9UJV9|DDX41_HUMAN 1 1642.9265 1.09 52769 19423 3 1642.925743 548.6494 Probable ATP-dependent RNA helicase DDX41 OS=Homo sapiens OX=9606 GN=DDX41 PE=1 SV=2 5.38 3223.7 - 1.92E+06 - - - -0.4656 - 3.556 0.617 - 649.9 1 2 0 -0.0008 14 0 0 0 3.62E+07 3.32E+07 - - - 8.7902 1 221125_WJC_METTL3_EV_vs_WT_F04.19425.19425.3 1.32E-11 32/56 A.PPSSNIEDFHGLLPK.G "sp|P43243|MATR3_HUMAN,tr|A8MXP9|A8MXP9_HUMAN,tr|D6R991|D6R991_HUMAN,tr|A0A0R4J2E8|A0A0R4J2E8_HUMAN,tr|H0Y8T4|H0Y8T4_HUMAN,tr|D6REM6|D6REM6_HUMAN" 6 1649.8413 1.44 52771 19425 3 1649.841837 550.9544 Matrin-3 OS=Homo sapiens OX=9606 GN=MATR3 PE=1 SV=2 5.33 3224 - 913477 - - - 0.3122 - 4.73 0.7 - 1507.6 1 1 0 0.0005 15 0 0 0 2.26E+08 1.57E+08 - - - 10.3989 0.9998 221125_WJC_METTL3_EV_vs_WT_F04.19429.19429.3 0.00977 Sep-40 K.SELHLLDFQGK[136.11].Q sp|Q9Y3A2|UTP11_HUMAN 1 1293.6809 1.35 52775 19429 3 1293.68276 432.2342 Probable U3 small nucleolar RNA-associated protein 11 OS=Homo sapiens OX=9606 GN=UTP11 PE=1 SV=2 5.3 3224.5 - 523902 - - - 1.4749 - 2.078 0.384 - 121.9 1 2 0 0.0019 11 0 0 0 5.19E+06 3.84E+06 - - - 4.8985 1 221125_WJC_METTL3_EV_vs_WT_F04.19430.19430.3 1.63E-09 15/52 R.FQSGDFHVINGVLR[166.11].T sp|P55060|XPO2_HUMAN 1 1597.824 0.53 52776 19430 3 1597.822963 533.6153 Exportin-2 OS=Homo sapiens OX=9606 GN=CSE1L PE=1 SV=3 6.74 3224.6 - 463436 - - - -0.6772 - 2.458 0.649 - 169.4 1 2 0 -0.0011 14 0 0 0 9.48E+06 1.79E+07 - - - 8.1655 0.8206 221125_WJC_METTL3_EV_vs_WT_F04.19431.19431.3 0.53 Sep-44 R.EKLNIGYIEDLK.A "sp|P05120|PAI2_HUMAN,tr|H7C004|H7C004_HUMAN,tr|H7BYS2|H7BYS2_HUMAN" 3 1433.7766 2.94 52777 19431 3 1433.773525 478.9328 Plasminogen activator inhibitor 2 OS=Homo sapiens OX=9606 GN=SERPINB2 PE=1 SV=2 4.68 3224.8 - 442054 - - - -2.1419 - 1.582 0.134 - 105.8 1 2 1 -0.0031 12 0 0 0 4.45E+06 1.52E+06 - - - 1.3045 1 221125_WJC_METTL3_EV_vs_WT_F04.19433.19433.3 7.16E-07 14/44 R.K[136.11]QININNPFVFK[136.11].H "sp|Q9UKF6|CPSF3_HUMAN,tr|G5E9W3|G5E9W3_HUMAN" 2 1476.8424 1.04 52779 19433 3 1476.8406 493.2881 Cleavage and polyadenylation specificity factor subunit 3 OS=Homo sapiens OX=9606 GN=CPSF3 PE=1 SV=1 10 3225 - 413587 - - - -1.208 - 2.767 0.533 - 343.9 1 2 0 -0.0018 12 0 0 0 5.70E+06 5.48E+06 - - - 7.303 0.9983 221125_WJC_METTL3_EV_vs_WT_F04.19434.19434.3 0.0374 Sep-40 K.SELHLLDFQGK.Q sp|Q9Y3A2|UTP11_HUMAN 1 1285.6667 1.35 52780 19434 3 1285.665205 429.5628 Probable U3 small nucleolar RNA-associated protein 11 OS=Homo sapiens OX=9606 GN=UTP11 PE=1 SV=2 5.3 3225.1 - 344832 - - - -1.1255 - 1.686 0.264 - 105 1 2 0 -0.0014 11 0 0 0 5.19E+06 3.84E+06 - - - 2.9669 1 221125_WJC_METTL3_EV_vs_WT_F04.19436.19436.3 2.20E-09 16/72 K.KVQGGALEDSQLVAGVAFK.K sp|Q99832|TCPH_HUMAN 1 1916.0367 0.17 52781 19436 3 1916.038927 639.6862 T-complex protein 1 subunit eta OS=Homo sapiens OX=9606 GN=CCT7 PE=1 SV=2 6.07 3225.4 - 902931 - - - 1.1482 - 3.404 0.514 - 363.4 1 2 0 0.0022 19 0 0 0 2.11E+07 1.21E+08 - - - 7.2794 1 221125_WJC_METTL3_EV_vs_WT_F04.19437.19437.2 2.34E-12 19/42 R.GPADSLSTAAGAAELSAEGAGK.S sp|Q7Z5L9|I2BP2_HUMAN 1 1929.928 1.64 52782 19437 2 1929.928752 965.9713 Interferon regulatory factor 2-binding protein 2 OS=Homo sapiens OX=9606 GN=IRF2BP2 PE=1 SV=2 4.14 3225.5 - 653543 - - - 0.4083 - 4.345 0.754 - 1076.6 1 2 0 0.0008 22 0 0 0 9.87E+07 6.03E+07 - - - 8.2215 1 221125_WJC_METTL3_EV_vs_WT_F04.19438.19438.3 2.04E-06 25/76 R.YVELFLNSTAGASGGAYEHR[166.11].Y "sp|P31943|HNRH1_HUMAN,tr|H0YB39|H0YB39_HUMAN,tr|G8JLB6|G8JLB6_HUMAN" 3 2151.0261 1.05 52783 19438 3 2151.024482 718.016 Heterogeneous nuclear ribonucleoprotein H OS=Homo sapiens OX=9606 GN=HNRNPH1 PE=1 SV=4 5.4 3225.6 - 1.13E+07 - - - -0.7299 - 4.583 0.661 - 606.2 1 2 0 -0.0016 20 0 0 0 7.34E+08 6.99E+08 - - - 9.6023 1 221125_WJC_METTL3_EV_vs_WT_F04.19439.19439.3 7.35E-12 22/84 K.YTPVQQGPVGVNVTYGGDPIPK[136.11].S "sp|P21333|FLNA_HUMAN,tr|A0A7P0NMY4|A0A7P0NMY4_HUMAN,tr|Q60FE5|Q60FE5_HUMAN" 3 2293.1834 1.09 52784 19439 3 2293.180526 765.4017 Filamin-A OS=Homo sapiens OX=9606 GN=FLNA PE=1 SV=4 5.83 3225.7 - 2.52E+06 - - - -1.2524 - 3.634 0.664 - 370.4 1 2 0 -0.0029 22 0 0 0 2.81E+07 2.57E+07 - - - 9.0013 1 221125_WJC_METTL3_EV_vs_WT_F04.19440.19440.3 6.29E-08 18/52 K.KADVDAIHEYLLLK.G sp|Q9UJV9|DDX41_HUMAN 1 1626.8981 1.27 52785 19440 3 1626.900389 543.3066 Probable ATP-dependent RNA helicase DDX41 OS=Homo sapiens OX=9606 GN=DDX41 PE=1 SV=2 5.38 3225.7 - 2.38E+06 - - - 1.4021 - 3.789 0.564 - 423.7 1 2 0 0.0023 14 0 0 0 4.20E+07 3.31E+07 - - - 8.3675 1 221125_WJC_METTL3_EV_vs_WT_F04.19441.19441.3 4.00E-07 14/56 R.INEMVHFDLPGQEER.E "sp|Q9NVI7|ATD3A_HUMAN,tr|Q5SV16|Q5SV16_HUMAN" 2 1812.8465 0.68 52786 19441 3 1812.850004 605.2894 ATPase family AAA domain-containing protein 3A OS=Homo sapiens OX=9606 GN=ATAD3A PE=1 SV=2 4.4 3225.8 - 1.76E+06 - - - 1.9422 - 3.073 0.511 - 324.3 1 2 0 0.0035 15 0 0 0 2.28E+07 3.33E+07 - - - 7.1656 0.9962 221125_WJC_METTL3_EV_vs_WT_F04.19443.19443.3 0.00842 Oct-36 K.DK[136.11]DFAIDIIK[136.11].S sp|Q15181|IPYR_HUMAN 1 1192.6674 0.34 52788 19443 3 1192.667145 398.5631 Inorganic pyrophosphatase OS=Homo sapiens OX=9606 GN=PPA1 PE=1 SV=2 4.43 3226 - 1.17E+06 - - - -0.2473 - 2.069 0.25 - 131.3 1 2 1 -0.0003 10 0 0 0 6.78E+06 2.01E+07 - - - 3.4505 1 221125_WJC_METTL3_EV_vs_WT_F04.19444.19444.4 0.000164 22/78 K.KADVDAIHEYLLLK.G sp|Q9UJV9|DDX41_HUMAN 1 1626.8981 0.92 52789 19444 4 1626.895511 407.7318 Probable ATP-dependent RNA helicase DDX41 OS=Homo sapiens OX=9606 GN=DDX41 PE=1 SV=2 5.38 3226.1 - 885528 - - - -1.5963 - 4.191 0.539 - 626.4 1 2 0 -0.0026 14 0 0 0 7.89E+06 8.61E+06 - - - 4.4382 0.9973 221125_WJC_METTL3_EV_vs_WT_F04.19446.19446.3 0.00818 Jul-36 K.DKDFAIDIIK.S sp|Q15181|IPYR_HUMAN 1 1176.639 0.34 52791 19446 3 1176.63722 393.2203 Inorganic pyrophosphatase OS=Homo sapiens OX=9606 GN=PPA1 PE=1 SV=2 4.43 3226.4 - 612538 - - - -1.5468 - 1.733 0.339 - 56.4 1 2 1 -0.0018 10 0 0 0 6.78E+06 2.01E+07 - - - 3.9248 0.9998 221125_WJC_METTL3_EV_vs_WT_F04.19449.19449.3 3.81E-06 14/52 K.HEQILVLDPPTDLK.F "sp|Q9P0L0|VAPA_HUMAN,tr|J3QKM9|J3QKM9_HUMAN" 2 1616.8774 1.15 52793 19449 3 1616.874016 539.9664 Vesicle-associated membrane protein-associated protein A OS=Homo sapiens OX=9606 GN=VAPA PE=1 SV=3 4.54 3226.7 - 251536 - - - -2.0762 - 2.536 0.381 - 236.5 1 2 0 -0.0034 14 0 0 0 8.10E+07 7.04E+07 - - - 5.2599 0.9998 221125_WJC_METTL3_EV_vs_WT_F04.19453.19453.2 1.38E-05 30-Dec K.ETSEELLPPPVQTQIK.G sp|Q8N183|NDUF2_HUMAN 1 1807.9567 2.02 52796 19453 2 1807.954473 904.9856 NADH dehydrogenase [ubiquinone] 1 alpha subcomplex assembly factor 2 OS=Homo sapiens OX=9606 GN=NDUFAF2 PE=1 SV=1 4.25 3227.2 - 1.21E+06 - - - -1.2567 - 2.122 0.555 - 212 1 2 0 -0.0023 16 0 0 0 1.01E+08 5.01E+07 - - - 4.9892 1 221125_WJC_METTL3_EV_vs_WT_F04.19454.19454.3 1.76E-12 25/72 K.LLFDETQGK[136.11]PAVAVIDNGR[166.11].G sp|A6NHR9|SMHD1_HUMAN 1 2060.1021 1.53 52797 19454 3 2060.099171 687.708 Structural maintenance of chromosomes flexible hinge domain-containing protein 1 OS=Homo sapiens OX=9606 GN=SMCHD1 PE=1 SV=2 4.56 3227.3 - 1.18E+06 - - - -1.4334 - 3.519 0.677 - 616.8 1 2 0 -0.003 19 0 0 0 1.62E+07 1.06E+07 - - - 9.1782 0.9997 221125_WJC_METTL3_EV_vs_WT_F04.19455.19455.4 0.000701 13/108 R.MDTLAHVLYYPQK[136.11]PLVTTR[166.11].S "sp|P30876|RPB2_HUMAN,tr|C9J4M6|C9J4M6_HUMAN,tr|C9J2Y9|C9J2Y9_HUMAN" 3 2263.2154 6.26 52798 19455 4 2263.213719 566.8111 DNA-directed RNA polymerase II subunit RPB2 OS=Homo sapiens OX=9606 GN=POLR2B PE=1 SV=1 8.27 3227.4 - 796664 - - - -0.7339 - 2.44 0.36 - 92.9 1 2 0 -0.0017 19 0 0 0 3.94E+07 6.29E+06 - - - 2.6607 1 221125_WJC_METTL3_EV_vs_WT_F04.19456.19456.3 1.28E-11 15/52 R.FQSGDFHVINGVLR.T sp|P55060|XPO2_HUMAN 1 1587.8158 0.53 52799 19456 3 1587.817929 530.2792 Exportin-2 OS=Homo sapiens OX=9606 GN=CSE1L PE=1 SV=3 6.74 3227.5 - 723298 - - - 1.3566 - 2.851 0.653 - 194 1 2 0 0.0022 14 0 0 0 9.30E+06 1.76E+07 - - - 8.6039 1 221125_WJC_METTL3_EV_vs_WT_F04.19457.19457.4 5.29E-09 19/78 K.K[136.11]ADVDAIHEYLLLK[136.11].G sp|Q9UJV9|DDX41_HUMAN 1 1642.9265 0.92 52800 19457 4 1642.92548 411.7389 Probable ATP-dependent RNA helicase DDX41 OS=Homo sapiens OX=9606 GN=DDX41 PE=1 SV=2 5.38 3227.6 - 570223 - - - -0.6257 - 3.672 0.548 - 400.1 1 2 0 -0.001 14 0 0 0 7.89E+06 8.61E+06 - - - 4.4689 0.9999 221125_WJC_METTL3_EV_vs_WT_F04.19458.19458.3 1.39E-05 Dec-44 R.KQININNPFVFK.H "sp|Q9UKF6|CPSF3_HUMAN,tr|G5E9W3|G5E9W3_HUMAN" 2 1460.814 1.04 52801 19458 3 1460.811325 487.9453 Cleavage and polyadenylation specificity factor subunit 3 OS=Homo sapiens OX=9606 GN=CPSF3 PE=1 SV=1 10 3227.8 - 535882 - - - -1.8202 - 2.424 0.392 - 239.1 1 2 0 -0.0027 12 0 0 0 5.70E+06 5.48E+06 - - - 5.3639 1 221125_WJC_METTL3_EV_vs_WT_F04.19459.19459.2 1.99E-12 16/40 K.GPNAAYDFSQAATTGELAANK.S sp|Q9Y5V3|MAGD1_HUMAN 1 2095.9811 2.36 52802 19459 2 2095.981778 1048.9978 Melanoma-associated antigen D1 OS=Homo sapiens OX=9606 GN=MAGED1 PE=1 SV=3 4.37 3227.9 - 444747 - - - 0.3411 - 4.102 0.73 - 840.8 1 2 0 0.0007 21 0 0 0 6.26E+06 2.65E+06 - - - 7.9027 1 221125_WJC_METTL3_EV_vs_WT_F04.19462.19462.3 5.22E-13 24/76 R.YVELFLNSTAGASGGAYEHR.Y "sp|P31943|HNRH1_HUMAN,tr|H0YB39|H0YB39_HUMAN,tr|G8JLB6|G8JLB6_HUMAN" 3 2141.0178 1.08 52803 19462 3 2141.020544 714.6799 Heterogeneous nuclear ribonucleoprotein H OS=Homo sapiens OX=9606 GN=HNRNPH1 PE=1 SV=4 5.4 3228.3 - 2.43E+07 - - - 1.29 - 4.061 0.691 - 606.2 1 2 0 0.0028 20 0 0 0 7.14E+08 6.61E+08 - - - 9.6431 1 221125_WJC_METTL3_EV_vs_WT_F04.19464.19464.3 4.56E-09 18/76 K.VNNASLIGLGYTQTLRPGVK.L sp|Q9Y277|VDAC3_HUMAN 1 2100.1691 1.4 52805 19464 3 2100.168926 701.0637 Voltage-dependent anion-selective channel protein 3 OS=Homo sapiens OX=9606 GN=VDAC3 PE=1 SV=1 9.99 3228.4 - 9.37E+06 - - - -0.1009 - 4.06 0.627 - 455 1 2 0 -0.0002 20 0 0 0 1.34E+08 9.60E+07 - - - 8.9297 0.9989 221125_WJC_METTL3_EV_vs_WT_F04.19465.19465.2 0.000284 17/22 R.NKLAELEEALQK.A "sp|P13647|K2C5_HUMAN,tr|H0YI76|H0YI76_HUMAN" 2 1384.7562 0.21 52806 19465 2 1384.757136 693.3854 "Keratin, type II cytoskeletal 5 OS=Homo sapiens OX=9606 GN=KRT5 PE=1 SV=3" 4.79 3228.5 - 1.63E+06 - - - 0.6795 - 3.202 0.487 - 1175.2 1 2 1 0.0009 12 0 0 0 4.73E+07 2.27E+08 - - - 5.6998 1 221125_WJC_METTL3_EV_vs_WT_F04.19466.19466.3 1.95E-07 20/60 K.ETSEELLPPPVQTQIK.G sp|Q8N183|NDUF2_HUMAN 1 1807.9567 1.71 52807 19466 3 1807.955916 603.6595 NADH dehydrogenase [ubiquinone] 1 alpha subcomplex assembly factor 2 OS=Homo sapiens OX=9606 GN=NDUFAF2 PE=1 SV=1 4.25 3228.6 - 1.48E+06 - - - -0.4585 - 3.214 0.517 - 562.5 1 2 0 -0.0008 16 0 0 0 7.60E+07 4.45E+07 - - - 7.2995 0.9999 221125_WJC_METTL3_EV_vs_WT_F04.19468.19468.3 9.25E-05 15/60 K.ETSEELLPPPVQTQIK[136.11].G sp|Q8N183|NDUF2_HUMAN 1 1815.9709 1.7 52809 19468 3 1815.971663 606.3309 NADH dehydrogenase [ubiquinone] 1 alpha subcomplex assembly factor 2 OS=Homo sapiens OX=9606 GN=NDUFAF2 PE=1 SV=1 4.25 3228.8 - 1.04E+06 - - - 0.3954 - 2.464 0.403 - 299.7 1 2 0 0.0007 16 0 0 0 7.58E+07 4.45E+07 - - - 5.3467 0.9965 221125_WJC_METTL3_EV_vs_WT_F04.19471.19471.3 0.0116 Oct-36 K.DRPFFPGLVK.Y "sp|O60361|NDK8_HUMAN,sp|P22392|NDKB_HUMAN,tr|Q32Q12|Q32Q12_HUMAN,tr|J3KPD9|J3KPD9_HUMAN,tr|F6XY72|F6XY72_HUMAN" 5 1174.6499 0.66 52812 19471 3 1174.647599 392.5572 Putative nucleoside diphosphate kinase OS=Homo sapiens OX=9606 GN=NME2P1 PE=5 SV=1 8.75 3229.2 - 570627 - - - -1.941 - 1.848 0.224 - 135.2 1 2 0 -0.0023 10 0 0 0 1.27E+07 1.91E+07 - - - 2.8302 0.9993 221125_WJC_METTL3_EV_vs_WT_F04.19473.19473.3 1.77E-06 17/60 R.FSHQGVQLIDFSPC[160.03]ER.Y "sp|P55884|EIF3B_HUMAN,tr|C9JQN7|C9JQN7_HUMAN" 2 1918.8996 1.23 52814 19473 3 1919.90383 640.6405 Eukaryotic translation initiation factor 3 subunit B OS=Homo sapiens OX=9606 GN=EIF3B PE=1 SV=3 5.32 3229.5 - 433193 - - - 523.3458 - 3.118 0.496 - 340.7 1 2 0 1.0042 16 0 0 0 3.91E+07 3.19E+07 - - - 6.7096 1 221125_WJC_METTL3_EV_vs_WT_F04.19477.19477.3 6.73E-09 16/64 K.GQGC[160.03]TAYDVAVNSDFYR.R "sp|Q9NWS0|PIHD1_HUMAN,tr|M0QYF4|M0QYF4_HUMAN,tr|M0QXD5|M0QXD5_HUMAN,tr|M0R3A4|M0R3A4_HUMAN,tr|M0R028|M0R028_HUMAN,tr|M0QZ61|M0QZ61_HUMAN,tr|M0QZM3|M0QZM3_HUMAN,tr|M0QYA2|M0QYA2_HUMAN" 8 1921.8265 1.51 52816 19477 3 1921.823896 641.6161 PIH1 domain-containing protein 1 OS=Homo sapiens OX=9606 GN=PIH1D1 PE=1 SV=1 4.21 3230 - 1.16E+06 - - - -1.3425 - 3.23 0.626 - 295.1 1 2 0 -0.0026 17 0 0 0 7.29E+07 4.82E+07 - - - 8.4806 1 221125_WJC_METTL3_EV_vs_WT_F04.19478.19478.3 2.18E-05 18/56 K.GQYFGELALVTNKPR.A "sp|P13861|KAP2_HUMAN,sp|P31323|KAP3_HUMAN,tr|H7C330|H7C330_HUMAN" 3 1691.8995 2.05 52817 19478 3 1691.900422 564.9738 cAMP-dependent protein kinase type II-alpha regulatory subunit OS=Homo sapiens OX=9606 GN=PRKAR2A PE=1 SV=2 8.59 3230 - 3.60E+06 - - - 0.542 - 3.099 0.555 - 438.7 1 2 0 0.0009 15 0 0 0 9.24E+07 4.50E+07 - - - 7.6788 1 221125_WJC_METTL3_EV_vs_WT_F04.19479.19479.3 4.52E-10 19/80 K.VKTEPTEDSGISLEMAAVTVK.E "sp|P78347|GTF2I_HUMAN,tr|A0A494C1K3|A0A494C1K3_HUMAN" 2 2204.1246 1.68 52818 19479 3 2204.125851 735.7155 General transcription factor II-I OS=Homo sapiens OX=9606 GN=GTF2I PE=1 SV=2 4.41 3230.1 - 2.25E+06 - - - 0.5608 - 3.521 0.651 - 474 1 2 1 0.0012 21 0 0 0 1.46E+08 8.66E+07 - - - 8.8154 1 221125_WJC_METTL3_EV_vs_WT_F04.19482.19482.2 5.70E-13 16/32 K.GQGC[160.03]TAYDVAVNSDFYR.R "sp|Q9NWS0|PIHD1_HUMAN,tr|M0QYF4|M0QYF4_HUMAN,tr|M0QXD5|M0QXD5_HUMAN,tr|M0R3A4|M0R3A4_HUMAN,tr|M0R028|M0R028_HUMAN,tr|M0QZ61|M0QZ61_HUMAN,tr|M0QZM3|M0QZM3_HUMAN,tr|M0QYA2|M0QYA2_HUMAN" 8 1921.8265 1.27 52821 19482 2 1921.822077 961.9205 PIH1 domain-containing protein 1 OS=Homo sapiens OX=9606 GN=PIH1D1 PE=1 SV=1 4.21 3230.5 - 1.20E+06 - - - -2.289 - 3.555 0.734 - 896.2 1 2 0 -0.0044 17 0 0 0 8.11E+07 6.39E+07 - - - 7.5793 1 221125_WJC_METTL3_EV_vs_WT_F04.19483.19483.3 2.02E-11 17/64 K.GQGC[160.03]TAYDVAVNSDFYR[166.11].R "sp|Q9NWS0|PIHD1_HUMAN,tr|M0QYF4|M0QYF4_HUMAN,tr|M0QXD5|M0QXD5_HUMAN,tr|M0R3A4|M0R3A4_HUMAN,tr|M0R028|M0R028_HUMAN,tr|M0QZ61|M0QZ61_HUMAN,tr|M0QZM3|M0QZM3_HUMAN,tr|M0QYA2|M0QYA2_HUMAN" 8 1931.8347 1.51 52822 19483 3 1931.83149 644.9522 PIH1 domain-containing protein 1 OS=Homo sapiens OX=9606 GN=PIH1D1 PE=1 SV=1 4.21 3230.6 - 1.18E+06 - - - -1.6854 - 3.172 0.689 - 331.3 1 2 0 -0.0033 17 0 0 0 7.29E+07 4.82E+07 - - - 9.137 0.9998 221125_WJC_METTL3_EV_vs_WT_F04.19484.19484.2 1.02E-05 30-Dec K.ETSEELLPPPVQTQIK[136.11].G sp|Q8N183|NDUF2_HUMAN 1 1815.9709 2.02 52823 19484 2 1815.967593 908.9927 NADH dehydrogenase [ubiquinone] 1 alpha subcomplex assembly factor 2 OS=Homo sapiens OX=9606 GN=NDUFAF2 PE=1 SV=1 4.25 3230.8 - 1.06E+06 - - - -1.8458 - 2.021 0.54 - 212.8 1 2 0 -0.0034 16 0 0 0 1.01E+08 5.01E+07 - - - 4.7582 1 221125_WJC_METTL3_EV_vs_WT_F04.19487.19487.3 5.91E-05 18/52 R.KLEAAEDIAYQLSR.S "sp|P35232|PHB_HUMAN,tr|C9JZ20|C9JZ20_HUMAN" 2 1605.8362 1.22 52826 19487 3 1605.836503 536.286 Prohibitin OS=Homo sapiens OX=9606 GN=PHB PE=1 SV=1 4.68 3231.1 - 609499 - - - 0.1663 - 3.137 0.519 - 560.9 1 2 0 0.0003 14 0 0 0 2.45E+08 2.01E+08 - - - 7.3645 0.9019 221125_WJC_METTL3_EV_vs_WT_F04.19489.19489.2 0.214 18-Aug K.DRPFFPGLVK.Y "sp|O60361|NDK8_HUMAN,sp|P22392|NDKB_HUMAN,tr|Q32Q12|Q32Q12_HUMAN,tr|J3KPD9|J3KPD9_HUMAN,tr|F6XY72|F6XY72_HUMAN" 5 1174.6499 0.51 52828 19489 2 1174.653676 588.3322 Putative nucleoside diphosphate kinase OS=Homo sapiens OX=9606 GN=NME2P1 PE=5 SV=1 8.75 3231.4 - 448845 - - - 3.2325 - 1.483 0.033 - 112.8 3 2 0 0.0038 10 0 0 0 6.25E+06 1.23E+07 - - - 0.1704 1 221125_WJC_METTL3_EV_vs_WT_F04.19494.19494.2 2.06E-12 18/32 K.GQGC[160.03]TAYDVAVNSDFYR[166.11].R "sp|Q9NWS0|PIHD1_HUMAN,tr|M0QYF4|M0QYF4_HUMAN,tr|M0QXD5|M0QXD5_HUMAN,tr|M0R3A4|M0R3A4_HUMAN,tr|M0R028|M0R028_HUMAN,tr|M0QZ61|M0QZ61_HUMAN,tr|M0QZM3|M0QZM3_HUMAN,tr|M0QYA2|M0QYA2_HUMAN" 8 1931.8347 1.27 52831 19494 2 1931.832629 966.9246 PIH1 domain-containing protein 1 OS=Homo sapiens OX=9606 GN=PIH1D1 PE=1 SV=1 4.21 3232.1 - 2.39E+06 - - - -1.0958 - 3.652 0.745 - 1073.9 1 2 0 -0.0021 17 0 0 0 8.11E+07 6.39E+07 - - - 7.7274 1 221125_WJC_METTL3_EV_vs_WT_F04.19495.19495.3 8.05E-07 Nov-56 R.GFC[160.03]FITYTDEEPVK[136.11]K[136.11].L "sp|O14979|HNRDL_HUMAN,tr|A0A087WUK2|A0A087WUK2_HUMAN" 2 1848.8939 1.41 52832 19495 3 1848.89234 617.3052 Heterogeneous nuclear ribonucleoprotein D-like OS=Homo sapiens OX=9606 GN=HNRNPDL PE=1 SV=3 4.68 3232.1 - 4.91E+06 - - - -0.8373 - 2.159 0.58 - 114.7 1 2 0 -0.0015 15 0 0 0 1.27E+08 9.04E+07 - - - 7.0143 1 221125_WJC_METTL3_EV_vs_WT_F04.19496.19496.3 0.000135 14/52 R.K[136.11]LEAAEDIAYQLSR[166.11].S "sp|P35232|PHB_HUMAN,tr|C9JZ20|C9JZ20_HUMAN" 2 1623.8587 1.22 52833 19496 3 1623.858365 542.2935 Prohibitin OS=Homo sapiens OX=9606 GN=PHB PE=1 SV=1 4.68 3232.2 - 2.51E+06 - - - -0.21 - 2.665 0.461 - 258.5 1 2 0 -0.0003 14 0 0 0 2.46E+08 2.01E+08 - - - 6.2845 1 221125_WJC_METTL3_EV_vs_WT_F04.19498.19498.3 1.29E-05 16/52 K.TSNHAIVLAQLITK[136.11].G sp|Q15067|ACOX1_HUMAN 1 1515.8864 1.07 52835 19498 3 1515.88677 506.3028 Peroxisomal acyl-coenzyme A oxidase 1 OS=Homo sapiens OX=9606 GN=ACOX1 PE=1 SV=3 8.44 3232.4 - 645392 - - - 0.2256 - 2.65 0.473 - 534.9 1 2 0 0.0003 14 0 0 0 1.40E+07 1.31E+07 - - - 6.4033 0.9668 221125_WJC_METTL3_EV_vs_WT_F04.19502.19502.3 1.84E-06 19/64 R.LQK[136.11]EEEIEFLYNENTVR[166.11].E "sp|P41252|SYIC_HUMAN,tr|A0A804HL54|A0A804HL54_HUMAN,tr|A0A804HKU1|A0A804HKU1_HUMAN,tr|A0A804HK69|A0A804HK69_HUMAN,tr|A0A804HIV9|A0A804HIV9_HUMAN,tr|A0A804HJN6|A0A804HJN6_HUMAN,tr|A0A804HHW9|A0A804HHW9_HUMAN,tr|A0A0A0MSX9|A0A0A0MSX9_HUMAN,tr|J3KR24|J3KR24_HUMAN,tr|A0A804HJ36|A0A804HJ36_HUMAN" 10 2171.0865 0.09 52837 19502 3 2172.080809 724.7028 "Isoleucine--tRNA ligase, cytoplasmic OS=Homo sapiens OX=9606 GN=IARS1 PE=1 SV=2" 4.33 3232.9 - 3.08E+06 - - - 457.9619 - 2.98 0.496 - 477.2 1 2 1 0.9943 17 0 0 0 3.86E+06 4.22E+07 - - - 6.553 0.9999 221125_WJC_METTL3_EV_vs_WT_F04.19504.19504.4 2.25E-06 14/108 K.VWIKPGAEQSFLYGNHVLK.S "sp|Q9Y221|NIP7_HUMAN,tr|J3QRR4|J3QRR4_HUMAN,tr|J3QRD6|J3QRD6_HUMAN" 3 2185.1684 2.19 52839 19504 4 2185.164989 547.2994 60S ribosome subunit biogenesis protein NIP7 homolog OS=Homo sapiens OX=9606 GN=NIP7 PE=1 SV=1 8.48 3233.1 - 2.17E+06 - - - -1.5656 - 2.625 0.44 - 115.2 1 2 0 -0.0034 19 0 0 0 3.54E+07 1.62E+07 - - - 3.3813 1 221125_WJC_METTL3_EV_vs_WT_F04.19506.19506.3 5.87E-06 15/56 K.LIQSEVALNDLHLTK[136.11].Q "sp|Q15643|TRIPB_HUMAN,tr|H0YJ97|H0YJ97_HUMAN" 2 1700.9552 0.27 52841 19506 3 1700.953965 567.9924 Thyroid receptor-interacting protein 11 OS=Homo sapiens OX=9606 GN=TRIP11 PE=1 SV=3 5.32 3233.3 - 957551 - - - -0.7472 - 2.536 0.459 - 176.2 1 2 0 -0.0013 15 0 0 0 5.13E+06 1.88E+07 - - - 6.0853 0.9995 221125_WJC_METTL3_EV_vs_WT_F04.19510.19510.3 3.75E-05 14/56 R.IQALEAELQAVSHSK[136.11].T sp|Q08378|GOGA3_HUMAN 1 1630.877 17.54 52843 19510 3 1630.871496 544.6329 Golgin subfamily A member 3 OS=Homo sapiens OX=9606 GN=GOLGA3 PE=1 SV=2 5.4 3233.9 - 435428 - - - -3.3657 - 2.435 0.387 - 161.4 1 2 0 -0.0055 15 0 0 0 1.12E+08 6.38E+06 - - - 5.1753 1 221125_WJC_METTL3_EV_vs_WT_F04.19511.19511.3 0.000285 17/52 K.TSNHAIVLAQLITK.G sp|Q15067|ACOX1_HUMAN 1 1507.8722 1.07 52844 19511 3 1507.873852 503.6314 Peroxisomal acyl-coenzyme A oxidase 1 OS=Homo sapiens OX=9606 GN=ACOX1 PE=1 SV=3 8.44 3234 - 1.10E+06 - - - 1.077 - 2.691 0.477 - 506.9 1 2 0 0.0016 14 0 0 0 1.40E+07 1.31E+07 - - - 6.4884 0.9998 221125_WJC_METTL3_EV_vs_WT_F04.19515.19515.3 4.28E-05 13/60 R.C[160.03]IPALDSLTPANEDQK.L "sp|P10809|CH60_HUMAN,tr|A0A7I2V2X6|A0A7I2V2X6_HUMAN,tr|A0A7I2YQK6|A0A7I2YQK6_HUMAN,tr|A0A7I2V599|A0A7I2V599_HUMAN" 4 1770.8458 999 52846 19515 3 1770.842537 591.2892 "60 kDa heat shock protein, mitochondrial OS=Homo sapiens OX=9606 GN=HSPD1 PE=1 SV=2" 4.03 3234.5 - 8.14E+06 - - - -1.8511 - 2.186 0.391 - 130.2 1 2 0 -0.0033 16 0 0 0 3.04E+08 0.00E+00 - - - 4.905 1 221125_WJC_METTL3_EV_vs_WT_F04.19516.19516.3 7.06E-09 23/68 K.VVTATLWGEDADK[136.11]FDGSR[166.11].Q "sp|P27694|RFA1_HUMAN,tr|I3L4R8|I3L4R8_HUMAN" 2 1983.9657 0.97 52847 19516 3 1983.960876 662.3292 Replication protein A 70 kDa DNA-binding subunit OS=Homo sapiens OX=9606 GN=RPA1 PE=1 SV=2 4.23 3234.6 - 2.29E+06 - - - -2.4265 - 3.973 0.638 - 569.6 1 2 1 -0.0048 18 0 0 0 2.64E+08 2.72E+08 - - - 9.0869 1 221125_WJC_METTL3_EV_vs_WT_F04.19517.19517.3 1.74E-12 20/68 R.GHVFEESQVAGTPMFVVK[136.11].A sp|P13639|EF2_HUMAN 1 1968.9859 0.36 52848 19517 3 1968.984545 657.3359 Elongation factor 2 OS=Homo sapiens OX=9606 GN=EEF2 PE=1 SV=4 5.4 3234.7 - 4.27E+06 - - - -0.68 - 3.822 0.663 - 726.5 1 2 0 -0.0013 18 0 0 0 8.15E+07 2.29E+08 - - - 9.2701 1 221125_WJC_METTL3_EV_vs_WT_F04.19518.19518.2 7.50E-10 21/26 R.K[136.11]LEAAEDIAYQLSR[166.11].S "sp|P35232|PHB_HUMAN,tr|C9JZ20|C9JZ20_HUMAN" 2 1623.8587 1.25 52849 19518 2 1623.858307 812.9366 Prohibitin OS=Homo sapiens OX=9606 GN=PHB PE=1 SV=1 4.68 3234.8 - 1.12E+06 - - - -0.2457 - 4.278 0.644 - 1656.9 1 2 0 -0.0004 14 0 0 0 3.96E+07 3.17E+07 - - - 7.4449 1 221125_WJC_METTL3_EV_vs_WT_F04.19522.19522.2 4.09E-07 22/26 R.KLEAAEDIAYQLSR.S "sp|P35232|PHB_HUMAN,tr|C9JZ20|C9JZ20_HUMAN" 2 1605.8362 1.25 52851 19522 2 1605.836168 803.9254 Prohibitin OS=Homo sapiens OX=9606 GN=PHB PE=1 SV=1 4.68 3235.4 - 1.20E+06 - - - -0.0423 - 4.334 0.653 - 1910.5 1 2 0 -0.0001 14 0 0 0 3.96E+07 3.17E+07 - - - 7.5441 0.9999 221125_WJC_METTL3_EV_vs_WT_F04.19523.19523.3 5.83E-08 19/56 K.NGFRPLDVSLYAQQR.Y sp|Q92615|LAR4B_HUMAN 1 1762.9115 0.83 52852 19523 3 1762.915988 588.6444 La-related protein 4B OS=Homo sapiens OX=9606 GN=LARP4B PE=1 SV=3 8.75 3235.5 - 1.83E+06 - - - 2.5645 - 2.989 0.486 - 468.5 1 2 0 0.0045 15 0 0 0 3.01E+08 3.61E+08 - - - 6.8143 0.9998 221125_WJC_METTL3_EV_vs_WT_F04.19524.19524.3 1.36E-05 Dec-40 R.HYDLNQLLEPR.S "sp|P52948|NUP98_HUMAN,tr|H7C3P6|H7C3P6_HUMAN,tr|H0YDF4|H0YDF4_HUMAN" 3 1396.7099 1.93 52853 19524 3 1396.706229 466.5772 Nuclear pore complex protein Nup98-Nup96 OS=Homo sapiens OX=9606 GN=NUP98 PE=1 SV=4 5.32 3235.7 - 446145 - - - -2.6376 - 2.496 0.415 - 263.9 1 2 0 -0.0037 11 0 0 0 2.76E+07 1.43E+07 - - - 5.7643 1 221125_WJC_METTL3_EV_vs_WT_F04.19527.19527.2 4.01E-11 16/36 A.AFASSLVSGLNSSASEPAK[136.11].E "sp|Q86U44|MTA70_HUMAN,tr|F5H6D8|F5H6D8_HUMAN,tr|H0YFV6|H0YFV6_HUMAN,tr|B4DTN4|B4DTN4_HUMAN" 4 1829.9251 0.001 52854 19527 2 1829.919928 915.9698 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 6.05 3236 - 802660 - - - -2.8034 - 3.612 0.581 - 636.6 1 1 0 -0.0051 19 0 0 0 0.00E+00 3.55E+07 - - - 6.4881 0.9994 221125_WJC_METTL3_EV_vs_WT_F04.19531.19531.3 0.0473 18/44 K.FDK[136.11]DHDVMLFLK[136.11].M "sp|Q93009|UBP7_HUMAN,tr|A0A669KBL1|A0A669KBL1_HUMAN,tr|H3BND8|H3BND8_HUMAN" 3 1522.7825 1.14 52857 19531 3 1522.776604 508.6014 Ubiquitin carboxyl-terminal hydrolase 7 OS=Homo sapiens OX=9606 GN=USP7 PE=1 SV=2 5.3 3236.5 - 819603 - - - -3.8627 - 3.24 0.474 - 238.6 1 2 1 -0.0059 12 0 0 0 1.82E+07 1.59E+07 - - - 7.0815 0.9994 221125_WJC_METTL3_EV_vs_WT_F04.19532.19532.3 8.54E-05 15/44 K.FDKDHDVMLFLK.M "sp|Q93009|UBP7_HUMAN,tr|A0A669KBL1|A0A669KBL1_HUMAN,tr|H3BND8|H3BND8_HUMAN" 3 1506.7541 1.14 52858 19532 3 1506.752249 503.2586 Ubiquitin carboxyl-terminal hydrolase 7 OS=Homo sapiens OX=9606 GN=USP7 PE=1 SV=2 5.3 3236.7 - 638930 - - - -1.2192 - 2.212 0.38 - 150.5 1 2 1 -0.0018 12 0 0 0 1.82E+07 1.59E+07 - - - 4.9767 0.9895 221125_WJC_METTL3_EV_vs_WT_F04.19533.19533.2 0.0514 24-Jul K.GSTLDLSDLEAEK[136.11].L sp|O00767|SCD_HUMAN 1 1384.6813 0.54 52859 19533 2 1384.677932 693.3479 Stearoyl-CoA desaturase OS=Homo sapiens OX=9606 GN=SCD PE=1 SV=2 3.92 3236.8 - 588738 - - - -2.4359 - 1.503 0.189 - 97.8 2 2 0 -0.0034 13 0 0 0 8.73E+06 1.60E+07 - - - 1.3472 1 221125_WJC_METTL3_EV_vs_WT_F04.19535.19535.3 1.10E-13 19/80 R.GAHGIIVVYDVTDQESYANVK.Q sp|Q9H0U4|RAB1B_HUMAN 1 2277.1277 1.02 52860 19535 3 2277.133086 760.0499 Ras-related protein Rab-1B OS=Homo sapiens OX=9606 GN=RAB1B PE=1 SV=1 4.54 3237 - 2.51E+06 - - - 2.3534 - 3.969 0.668 - 470.9 1 2 0 0.0054 21 0 0 0 7.99E+07 7.82E+07 - - - 9.291 1 221125_WJC_METTL3_EV_vs_WT_F04.19537.19537.3 9.64E-12 18/80 K.VK[136.11]TEPTEDSGISLEMAAVTVK[136.11].E "sp|P78347|GTF2I_HUMAN,tr|A0A494C1K3|A0A494C1K3_HUMAN" 2 2220.153 1.68 52861 19537 3 2220.156887 741.0583 General transcription factor II-I OS=Homo sapiens OX=9606 GN=GTF2I PE=1 SV=2 4.41 3237.2 - 3.24E+06 - - - 1.744 - 3.277 0.671 - 430.8 1 2 1 0.0039 21 0 0 0 1.46E+08 8.66E+07 - - - 8.8655 0.8457 221125_WJC_METTL3_EV_vs_WT_F04.19540.19540.3 0.4 Oct-48 R.SVFALTNGIYPHK[136.11].L sp|Q02878|RL6_HUMAN 1 1453.7809 1.17 52864 19540 3 1453.778914 485.6009 60S ribosomal protein L6 OS=Homo sapiens OX=9606 GN=RPL6 PE=1 SV=3 8.33 3237.6 - 632557 - - - -1.3661 - 1.412 0.072 - 66.9 1 2 0 -0.002 13 0 0 0 8.76E+06 7.48E+06 - - - 0.2776 1 221125_WJC_METTL3_EV_vs_WT_F04.19544.19544.2 3.37E-10 15/30 R.C[160.03]IPALDSLTPANEDQK[136.11].L "sp|P10809|CH60_HUMAN,tr|A0A7I2V2X6|A0A7I2V2X6_HUMAN,tr|A0A7I2YQK6|A0A7I2YQK6_HUMAN,tr|A0A7I2V599|A0A7I2V599_HUMAN" 4 1778.86 0.92 52866 19544 2 1778.854484 890.4373 "60 kDa heat shock protein, mitochondrial OS=Homo sapiens OX=9606 GN=HSPD1 PE=1 SV=2" 4.03 3238.1 - 1.72E+07 - - - -3.1093 - 2.648 0.69 - 424.3 1 2 0 -0.0055 16 0 0 0 6.87E+08 7.43E+08 - - - 6.5297 0.8781 221125_WJC_METTL3_EV_vs_WT_F04.19545.19545.2 0.116 Aug-32 R.GAPPSSNIEDFHGLLPK[136.11].G "sp|P43243|MATR3_HUMAN,tr|A8MXP9|A8MXP9_HUMAN,tr|D6R991|D6R991_HUMAN,tr|A0A0R4J2E8|A0A0R4J2E8_HUMAN,tr|H0Y8T4|H0Y8T4_HUMAN,tr|D6REM6|D6REM6_HUMAN" 6 1785.9141 1.42 52867 19545 2 1786.917541 893.9643 Matrin-3 OS=Homo sapiens OX=9606 GN=MATR3 PE=1 SV=2 5.32 3238.2 - 2.83E+06 - - - 561.8646 - 1.43 0.242 - 107.7 1 2 0 1.0034 17 0 0 0 1.36E+08 9.57E+07 - - - 1.3927 0.9999 221125_WJC_METTL3_EV_vs_WT_F04.19549.19549.3 3.10E-06 Nov-40 R.HYDLNQLLEPR[166.11].S "sp|P52948|NUP98_HUMAN,tr|H7C3P6|H7C3P6_HUMAN,tr|H0YDF4|H0YDF4_HUMAN" 3 1406.7182 1.86 52871 19549 3 1406.717575 469.9133 Nuclear pore complex protein Nup98-Nup96 OS=Homo sapiens OX=9606 GN=NUP98 PE=1 SV=4 5.32 3238.6 - 485683 - - - -0.4322 - 2.066 0.436 - 208.5 1 2 0 -0.0006 11 0 0 0 2.61E+07 1.41E+07 - - - 5.4621 0.9999 221125_WJC_METTL3_EV_vs_WT_F04.19554.19554.3 0.00393 Dec-36 R.KDAEEWFFTK.T sp|P02533|K1C14_HUMAN 1 1299.6136 999 52874 19554 3 1299.613721 434.2118 "Keratin, type I cytoskeletal 14 OS=Homo sapiens OX=9606 GN=KRT14 PE=1 SV=4" 4.68 3239.3 - 1.99E+06 - - - 0.1293 - 2.3 0.398 - 211.2 1 2 0 0.0002 10 0 0 0 8.00E+07 0.00E+00 - - - 5.4097 1 221125_WJC_METTL3_EV_vs_WT_F04.19555.19555.3 4.22E-11 22/80 K.LVSDGQALPEMEIHLQTNAEK.G sp|Q12931|TRAP1_HUMAN 1 2322.1526 2.18 52875 19555 3 2322.150576 775.0581 "Heat shock protein 75 kDa, mitochondrial OS=Homo sapiens OX=9606 GN=TRAP1 PE=1 SV=3" 4.4 3239.4 - 1.90E+06 - - - -0.8548 - 3.684 0.631 - 441.7 1 2 0 -0.002 21 0 0 0 6.74E+07 3.09E+07 - - - 8.7008 0.9999 221125_WJC_METTL3_EV_vs_WT_F04.19557.19557.3 7.81E-05 Nov-40 R.GFC[160.03]FLEYEDHK.T "sp|O60506|HNRPQ_HUMAN,sp|O43390|HNRPR_HUMAN,tr|A0A7I2YQV8|A0A7I2YQV8_HUMAN,tr|B4DT28|B4DT28_HUMAN,tr|A0A7I2YQN2|A0A7I2YQN2_HUMAN,tr|A0A7I2V5Q6|A0A7I2V5Q6_HUMAN,tr|A0A7I2V4Z0|A0A7I2V4Z0_HUMAN,tr|A0A6Q8PHG0|A0A6Q8PHG0_HUMAN,tr|B7Z645|B7Z645_HUMAN,tr|A0A6Q8PH31|A0A6Q8PH31_HUMAN,tr|A0A6Q8PEX7|A0A6Q8PEX7_HUMAN,tr|A0A7I2V2F2|A0A7I2V2F2_HUMAN,tr|A0A7I2V346|A0A7I2V346_HUMAN,tr|A0A7I2V309|A0A7I2V309_HUMAN" 14 1443.6129 1.37 52877 19557 3 1443.611019 482.2116 Heterogeneous nuclear ribonucleoprotein Q OS=Homo sapiens OX=9606 GN=SYNCRIP PE=1 SV=2 4.65 3239.7 - 551126 - - - -1.3044 - 1.831 0.475 - 108.3 1 2 0 -0.0019 11 0 0 0 3.34E+07 2.44E+07 - - - 5.5536 0.9999 221125_WJC_METTL3_EV_vs_WT_F04.19558.19558.3 0.00194 Dec-40 R.GFC[160.03]FLEYEDHK[136.11].T "sp|O60506|HNRPQ_HUMAN,sp|O43390|HNRPR_HUMAN,tr|A0A7I2YQV8|A0A7I2YQV8_HUMAN,tr|B4DT28|B4DT28_HUMAN,tr|A0A7I2YQN2|A0A7I2YQN2_HUMAN,tr|A0A7I2V5Q6|A0A7I2V5Q6_HUMAN,tr|A0A7I2V4Z0|A0A7I2V4Z0_HUMAN,tr|A0A6Q8PHG0|A0A6Q8PHG0_HUMAN,tr|B7Z645|B7Z645_HUMAN,tr|A0A6Q8PH31|A0A6Q8PH31_HUMAN,tr|A0A6Q8PEX7|A0A6Q8PEX7_HUMAN,tr|A0A7I2V2F2|A0A7I2V2F2_HUMAN,tr|A0A7I2V346|A0A7I2V346_HUMAN,tr|A0A7I2V309|A0A7I2V309_HUMAN" 14 1451.6271 1.3 52878 19558 3 1451.62423 484.883 Heterogeneous nuclear ribonucleoprotein Q OS=Homo sapiens OX=9606 GN=SYNCRIP PE=1 SV=2 4.65 3239.8 - 541268 - - - -1.9785 - 1.878 0.459 - 126.3 1 2 0 -0.0029 11 0 0 0 3.16E+07 2.44E+07 - - - 5.4469 0.9963 221125_WJC_METTL3_EV_vs_WT_F04.19559.19559.4 0.000104 13/66 K.FDK[136.11]DHDVMLFLK[136.11].M "sp|Q93009|UBP7_HUMAN,tr|A0A669KBL1|A0A669KBL1_HUMAN,tr|H3BND8|H3BND8_HUMAN" 3 1522.7825 0.001 52879 19559 4 1522.77812 381.7029 Ubiquitin carboxyl-terminal hydrolase 7 OS=Homo sapiens OX=9606 GN=USP7 PE=1 SV=2 5.3 3239.9 - 526785 - - - -2.8671 - 2.333 0.344 - 123.6 1 2 1 -0.0044 12 0 0 0 0.00E+00 7.19E+06 - - - 2.5396 1 221125_WJC_METTL3_EV_vs_WT_F04.19562.19562.3 2.60E-07 16/72 K.EAEDVIWEDSASENQEGLR.K sp|O75792|RNH2A_HUMAN 1 2175.9556 2.98 52880 19562 3 2175.955403 726.3258 Ribonuclease H2 subunit A OS=Homo sapiens OX=9606 GN=RNASEH2A PE=1 SV=2 3.71 3240.4 - 1.17E+06 - - - -0.1071 - 3.146 0.598 - 381.1 1 2 0 -0.0002 19 0 0 0 1.85E+07 6.20E+06 - - - 8.0229 0.9921 221125_WJC_METTL3_EV_vs_WT_F04.19563.19563.2 2.66E-07 14/28 K.NGFRPLDVSLYAQQR.Y sp|Q92615|LAR4B_HUMAN 1 1762.9115 999 52881 19563 2 1762.898778 882.463 La-related protein 4B OS=Homo sapiens OX=9606 GN=LARP4B PE=1 SV=3 8.75 3240.6 - 1.15E+06 - - - -7.1978 - 2.488 0.558 - 176.4 1 2 0 -0.0127 15 0 0 0 1.16E+07 0.00E+00 - - - 5.3993 0.9976 221125_WJC_METTL3_EV_vs_WT_F04.19566.19566.3 0.00102 Dec-56 K.YKDNPFSLGESFGSR.W "sp|Q8N6H7|ARFG2_HUMAN,tr|E9PMU9|E9PMU9_HUMAN,tr|E9PQP3|E9PQP3_HUMAN,tr|H0YDN9|H0YDN9_HUMAN,tr|G5E9L0|G5E9L0_HUMAN,tr|A0A0D9SF70|A0A0D9SF70_HUMAN" 6 1702.7951 1.58 52884 19566 3 1702.791849 568.6056 ADP-ribosylation factor GTPase-activating protein 2 OS=Homo sapiens OX=9606 GN=ARFGAP2 PE=1 SV=1 6.07 3240.9 - 772895 - - - -1.9092 - 2.166 0.326 - 184.5 1 2 1 -0.0033 15 0 0 0 6.39E+07 4.05E+07 - - - 4.1904 0.9998 221125_WJC_METTL3_EV_vs_WT_F04.19571.19571.3 1.29E-06 15/64 R.ITFDAFPGEPDKELNPK.K sp|Q12904|AIMP1_HUMAN 1 1916.952 1.55 52887 19571 3 1916.954187 639.9913 Aminoacyl tRNA synthase complex-interacting multifunctional protein 1 OS=Homo sapiens OX=9606 GN=AIMP1 PE=1 SV=2 4.32 3241.5 - 3.10E+06 - - - 1.144 - 2.495 0.512 - 227.6 1 2 1 0.0022 17 0 0 0 1.41E+08 9.08E+07 - - - 6.5575 0.9995 221125_WJC_METTL3_EV_vs_WT_F04.19573.19573.3 2.17E-05 Dec-64 R.ITFDAFPGEPDK[136.11]ELNPK[136.11].K sp|Q12904|AIMP1_HUMAN 1 1932.9804 1.56 52889 19573 3 1932.976463 645.3341 Aminoacyl tRNA synthase complex-interacting multifunctional protein 1 OS=Homo sapiens OX=9606 GN=AIMP1 PE=1 SV=2 4.32 3241.7 - 2.46E+06 - - - -2.0336 - 2.254 0.453 - 143.5 1 2 1 -0.0039 17 0 0 0 1.41E+08 9.08E+07 - - - 5.6426 1 221125_WJC_METTL3_EV_vs_WT_F04.19574.19574.2 9.57E-13 20/34 K.VVTATLWGEDADKFDGSR.Q "sp|P27694|RFA1_HUMAN,tr|I3L4R8|I3L4R8_HUMAN" 2 1965.9432 1.62 52890 19574 2 1965.946976 983.9789 Replication protein A 70 kDa DNA-binding subunit OS=Homo sapiens OX=9606 GN=RPA1 PE=1 SV=2 4.23 3241.8 - 681881 - - - 1.9105 - 3.558 0.705 - 1322 1 2 1 0.0038 18 0 0 0 8.66E+06 5.33E+06 - - - 7.3673 0.9986 221125_WJC_METTL3_EV_vs_WT_F04.19575.19575.3 2.42E-07 16/72 K.EAEDVIWEDSASENQEGLR[166.11].K sp|O75792|RNH2A_HUMAN 1 2185.9639 2.98 52891 19575 3 2186.962005 729.6619 Ribonuclease H2 subunit A OS=Homo sapiens OX=9606 GN=RNASEH2A PE=1 SV=2 3.71 3241.9 - 667084 - - - 456.5945 - 2.811 0.563 - 362.3 1 2 0 0.9981 19 0 0 0 1.85E+07 6.20E+06 - - - 7.0796 1 221125_WJC_METTL3_EV_vs_WT_F04.19576.19576.3 4.04E-06 Nov-36 R.R[166.11]APFDLFENK[136.11].K "sp|P08238|HS90B_HUMAN,sp|Q58FF7|H90B3_HUMAN" 2 1253.6523 0.86 52892 19576 3 1253.652476 418.8914 Heat shock protein HSP 90-beta OS=Homo sapiens OX=9606 GN=HSP90AB1 PE=1 SV=4 6.07 3242.1 - 464964 - - - 0.1069 - 2.467 0.482 - 196.8 1 2 0 0.0001 10 0 0 0 1.50E+07 1.75E+07 - - - 6.5509 1 221125_WJC_METTL3_EV_vs_WT_F04.19581.19581.3 6.06E-12 24/76 R.VINEPTAAALAYGLDKSEDK.V "sp|P38646|GRP75_HUMAN,tr|H0Y8K0|H0Y8K0_HUMAN,tr|A0A7I2V2S7|A0A7I2V2S7_HUMAN,tr|A0A7I2V2G2|A0A7I2V2G2_HUMAN,tr|A0A7I2V3F7|A0A7I2V3F7_HUMAN,tr|A0A7I2YQB2|A0A7I2YQB2_HUMAN,tr|D6RCD7|D6RCD7_HUMAN" 7 2104.0688 0.62 52895 19581 3 2104.069047 702.3635 "Stress-70 protein, mitochondrial OS=Homo sapiens OX=9606 GN=HSPA9 PE=1 SV=2" 4.32 3242.6 - 1.95E+06 - - - 0.1103 - 4.283 0.624 - 533.2 1 2 1 0.0002 20 0 0 0 1.15E+08 1.86E+08 - - - 9.0259 0.9999 221125_WJC_METTL3_EV_vs_WT_F04.19588.19588.3 0.000164 Dec-44 K.QDFVQHFSQIVR[166.11].V "sp|P14324|FPPS_HUMAN,tr|A0A087WTP2|A0A087WTP2_HUMAN,tr|A0A087WVN4|A0A087WVN4_HUMAN,tr|A0A087X1D8|A0A087X1D8_HUMAN" 4 1512.7713 1.6 52902 19588 3 1512.770935 505.2644 Farnesyl pyrophosphate synthase OS=Homo sapiens OX=9606 GN=FDPS PE=1 SV=4 6.74 3243.4 - 456620 - - - -0.2294 - 1.878 0.422 - 159.4 1 2 0 -0.0003 12 0 0 0 1.43E+07 8.97E+06 - - - 4.9916 0.9999 221125_WJC_METTL3_EV_vs_WT_F04.19590.19590.2 8.90E-05 13/30 R.C[160.03]IPALDSLTPANEDQK.L "sp|P10809|CH60_HUMAN,tr|A0A7I2V2X6|A0A7I2V2X6_HUMAN,tr|A0A7I2YQK6|A0A7I2YQK6_HUMAN,tr|A0A7I2V599|A0A7I2V599_HUMAN" 4 1770.8458 1.1 52903 19590 2 1770.846323 886.4302 "60 kDa heat shock protein, mitochondrial OS=Homo sapiens OX=9606 GN=HSPD1 PE=1 SV=2" 4.03 3243.6 - 3.19E+07 - - - 0.2869 - 2.276 0.538 - 280.6 1 2 0 0.0005 16 0 0 0 6.87E+08 6.26E+08 - - - 5.0365 1 221125_WJC_METTL3_EV_vs_WT_F04.19592.19592.3 4.02E-07 13/64 R.GAPPSSNIEDFHGLLPK[136.11].G "sp|P43243|MATR3_HUMAN,tr|A8MXP9|A8MXP9_HUMAN,tr|D6R991|D6R991_HUMAN,tr|A0A0R4J2E8|A0A0R4J2E8_HUMAN,tr|H0Y8T4|H0Y8T4_HUMAN,tr|D6REM6|D6REM6_HUMAN" 6 1785.9141 1.45 52905 19592 3 1785.911416 596.312 Matrin-3 OS=Homo sapiens OX=9606 GN=MATR3 PE=1 SV=2 5.32 3243.7 - 1.12E+08 - - - -1.5023 - 2.552 0.563 - 149.1 1 2 0 -0.0027 17 0 0 0 7.52E+09 5.17E+09 - - - 7.183 0.9999 221125_WJC_METTL3_EV_vs_WT_F04.19593.19593.3 0.00117 17/80 K.LVSDGQALPEMEIHLQTNAEK[136.11].G sp|Q12931|TRAP1_HUMAN 1 2330.1668 2.18 52906 19593 3 2330.16431 777.7295 "Heat shock protein 75 kDa, mitochondrial OS=Homo sapiens OX=9606 GN=TRAP1 PE=1 SV=3" 4.4 3243.8 - 2.86E+06 - - - -1.0519 - 2.483 0.397 - 170.6 1 2 0 -0.0025 21 0 0 0 6.74E+07 3.09E+07 - - - 5.1459 1 221125_WJC_METTL3_EV_vs_WT_F04.19595.19595.3 9.46E-10 22/68 R.TSQQLQLIDEQDSYIQSR[166.11].A "sp|Q13190|STX5_HUMAN,tr|H7C3X5|H7C3X5_HUMAN" 2 2161.0527 1.59 52908 19595 3 2161.049473 721.3582 Syntaxin-5 OS=Homo sapiens OX=9606 GN=STX5 PE=1 SV=2 4.03 3244 - 1.77E+06 - - - -1.4752 - 3.353 0.602 - 857.8 1 2 0 -0.0032 18 0 0 0 3.92E+07 2.46E+07 - - - 8.2635 0.9672 221125_WJC_METTL3_EV_vs_WT_F04.19596.19596.3 3.45E-05 Oct-56 K.QC[160.03]ADLETAIADAEQR.G sp|Q14CN4|K2C72_HUMAN 1 1689.7628 0.45 52909 19596 3 1689.75043 564.2615 "Keratin, type II cytoskeletal 72 OS=Homo sapiens OX=9606 GN=KRT72 PE=1 SV=2" 3.92 3244.1 - 1.50E+06 - - - -7.3282 - 2.346 0.284 - 156.4 1 2 0 -0.0124 15 0 0 0 2.48E+07 5.48E+07 - - - 3.9279 1 221125_WJC_METTL3_EV_vs_WT_F04.19598.19598.3 8.96E-10 15/84 R.DKVLTAEELNAAQTSVAYGC[160.03]IK.Y sp|P54136|SYRC_HUMAN 1 2380.1944 2.51 52911 19598 3 2380.188442 794.4054 "Arginine--tRNA ligase, cytoplasmic OS=Homo sapiens OX=9606 GN=RARS1 PE=1 SV=2" 4.68 3244.4 - 911478 - - - -2.5145 - 4.005 0.607 - 262.1 1 2 1 -0.006 22 0 0 0 5.01E+06 1.99E+06 - - - 8.5954 1 221125_WJC_METTL3_EV_vs_WT_F04.19599.19599.2 6.56E-06 20/26 P.PSSNIEDFHGLLPK[136.11].G "sp|P43243|MATR3_HUMAN,tr|A8MXP9|A8MXP9_HUMAN,tr|D6R991|D6R991_HUMAN,tr|A0A0R4J2E8|A0A0R4J2E8_HUMAN,tr|H0Y8T4|H0Y8T4_HUMAN,tr|D6REM6|D6REM6_HUMAN" 6 1560.8028 1.16 52912 19599 2 1560.7984 781.4087 Matrin-3 OS=Homo sapiens OX=9606 GN=MATR3 PE=1 SV=2 5.33 3244.5 - 742256 - - - -2.7922 - 3.735 0.62 - 1191.9 1 1 0 -0.0044 14 0 0 0 2.70E+07 2.32E+07 - - - 6.9258 1 221125_WJC_METTL3_EV_vs_WT_F04.19600.19600.3 1.12E-07 20/44 R.FATSEELLSHLR[166.11].T "sp|Q9H7S9|ZN703_HUMAN,sp|Q96F45|ZN503_HUMAN" 2 1411.7335 1.59 52913 19600 3 1411.734291 471.5851 Zinc finger protein 703 OS=Homo sapiens OX=9606 GN=ZNF703 PE=1 SV=1 5.4 3244.6 - 712668 - - - 0.561 - 2.891 0.527 - 420 1 2 0 0.0008 12 0 0 0 2.81E+07 1.77E+07 - - - 7.3579 1 221125_WJC_METTL3_EV_vs_WT_F04.19601.19601.2 8.69E-13 17/36 R.FDSNNVVLIEDNGNPVGTR.L sp|Q6P1L8|RM14_HUMAN 1 2058.997 1.28 52914 19601 2 2058.991555 1030.5058 "39S ribosomal protein L14, mitochondrial OS=Homo sapiens OX=9606 GN=MRPL14 PE=1 SV=1" 4.03 3244.7 - 654322 - - - -2.6673 - 3.54 0.67 - 606.7 1 2 0 -0.0055 19 0 0 0 9.13E+06 7.13E+06 - - - 7.0958 1 221125_WJC_METTL3_EV_vs_WT_F04.19603.19603.3 1.58E-06 13/64 R.GAPPSSNIEDFHGLLPK.G "sp|P43243|MATR3_HUMAN,tr|A8MXP9|A8MXP9_HUMAN,tr|D6R991|D6R991_HUMAN,tr|A0A0R4J2E8|A0A0R4J2E8_HUMAN,tr|H0Y8T4|H0Y8T4_HUMAN,tr|D6REM6|D6REM6_HUMAN" 6 1777.8999 1.42 52915 19603 3 1777.900432 593.6406 Matrin-3 OS=Homo sapiens OX=9606 GN=MATR3 PE=1 SV=2 5.32 3245 - 1.60E+08 - - - 0.2998 - 2.49 0.57 - 162.5 1 2 0 0.0005 17 0 0 0 5.81E+09 4.08E+09 - - - 7.1995 1 221125_WJC_METTL3_EV_vs_WT_F04.19605.19605.3 5.47E-09 24/76 R.VINEPTAAALAYGLDK[136.11]SEDK[136.11].V "sp|P38646|GRP75_HUMAN,tr|H0Y8K0|H0Y8K0_HUMAN,tr|A0A7I2V2S7|A0A7I2V2S7_HUMAN,tr|A0A7I2V2G2|A0A7I2V2G2_HUMAN,tr|A0A7I2V3F7|A0A7I2V3F7_HUMAN,tr|A0A7I2YQB2|A0A7I2YQB2_HUMAN,tr|D6RCD7|D6RCD7_HUMAN" 7 2120.0972 0.62 52916 19605 3 2120.095678 707.7063 "Stress-70 protein, mitochondrial OS=Homo sapiens OX=9606 GN=HSPA9 PE=1 SV=2" 4.32 3245.2 - 1.55E+07 - - - -0.725 - 4.084 0.622 - 512.3 1 2 1 -0.0015 20 0 0 0 1.15E+08 1.86E+08 - - - 8.8879 0.9415 221125_WJC_METTL3_EV_vs_WT_F04.19606.19606.3 0.101 Jul-56 K.YK[136.11]DNPFSLGESFGSR[166.11].W "sp|Q8N6H7|ARFG2_HUMAN,tr|E9PMU9|E9PMU9_HUMAN,tr|E9PQP3|E9PQP3_HUMAN,tr|H0YDN9|H0YDN9_HUMAN,tr|G5E9L0|G5E9L0_HUMAN,tr|A0A0D9SF70|A0A0D9SF70_HUMAN" 6 1720.8176 1.58 52917 19606 3 1720.821867 574.6131 ADP-ribosylation factor GTPase-activating protein 2 OS=Homo sapiens OX=9606 GN=ARFGAP2 PE=1 SV=1 6.07 3245.2 - 3.04E+06 - - - 2.4971 - 1.43 0.248 - 43.5 1 2 1 0.0043 15 0 0 0 6.37E+07 4.03E+07 - - - 2.2371 0.9984 221125_WJC_METTL3_EV_vs_WT_F04.19608.19608.3 8.95E-09 19/72 R.FDSNNVVLIEDNGNPVGTR[166.11].L sp|Q6P1L8|RM14_HUMAN 1 2069.0053 1.5 52919 19608 3 2070.014168 690.6757 "39S ribosomal protein L14, mitochondrial OS=Homo sapiens OX=9606 GN=MRPL14 PE=1 SV=1" 4.03 3245.4 - 1.76E+06 - - - 487.6019 - 3.57 0.523 - 393.7 1 2 0 1.0089 19 0 0 0 2.06E+07 1.37E+07 - - - 7.2179 1 221125_WJC_METTL3_EV_vs_WT_F04.19609.19609.3 0.000381 17/44 R.FATSEELLSHLR.T "sp|Q9H7S9|ZN703_HUMAN,sp|Q96F45|ZN503_HUMAN" 2 1401.7252 1.59 52920 19609 3 1401.724807 468.249 Zinc finger protein 703 OS=Homo sapiens OX=9606 GN=ZNF703 PE=1 SV=1 5.4 3245.4 - 1.45E+06 - - - -0.3011 - 2.73 0.491 - 269.9 1 2 0 -0.0004 12 0 0 0 2.81E+07 1.77E+07 - - - 6.7978 0.9996 221125_WJC_METTL3_EV_vs_WT_F04.19610.19610.3 0.00144 14/56 R.ANQLAEEIESSAQYK.A "sp|Q99700|ATX2_HUMAN,tr|F8W0B5|F8W0B5_HUMAN,tr|A0A5F9ZHW5|A0A5F9ZHW5_HUMAN,tr|A0A5F9ZHH4|A0A5F9ZHH4_HUMAN,tr|A0A5F9ZI57|A0A5F9ZI57_HUMAN,tr|A0A2R8YDM9|A0A2R8YDM9_HUMAN,tr|F8VQP2|F8VQP2_HUMAN,tr|A0A2R8Y5A6|A0A2R8Y5A6_HUMAN,tr|F8WB06|F8WB06_HUMAN,tr|A0A5F9ZH85|A0A5F9ZH85_HUMAN,tr|F8VRK6|F8VRK6_HUMAN,tr|V9GY86|V9GY86_HUMAN,tr|A0A2R8Y7E6|A0A2R8Y7E6_HUMAN,tr|A0A5F9ZHX3|A0A5F9ZHX3_HUMAN,tr|H0YH87|H0YH87_HUMAN,tr|A0A2R8Y7P6|A0A2R8Y7P6_HUMAN" 16 1679.8002 1.36 52921 19610 3 1679.799687 560.9407 Ataxin-2 OS=Homo sapiens OX=9606 GN=ATXN2 PE=1 SV=2 4.25 3245.5 - 903616 - - - -0.3322 - 1.925 0.334 - 226.6 1 2 0 -0.0006 15 0 0 0 1.66E+07 1.23E+07 - - - 3.9726 1 221125_WJC_METTL3_EV_vs_WT_F04.19611.19611.2 1.35E-10 15/36 R.FDSNNVVLIEDNGNPVGTR[166.11].L sp|Q6P1L8|RM14_HUMAN 1 2069.0053 1.28 52922 19611 2 2069.002279 1035.5099 "39S ribosomal protein L14, mitochondrial OS=Homo sapiens OX=9606 GN=MRPL14 PE=1 SV=1" 4.03 3245.6 - 783868 - - - -1.4683 - 3.11 0.631 - 596.2 1 2 0 -0.003 19 0 0 0 9.13E+06 7.13E+06 - - - 6.4901 1 221125_WJC_METTL3_EV_vs_WT_F04.19613.19613.3 3.47E-06 14/36 R.RAPFDLFENK.K "sp|P08238|HS90B_HUMAN,sp|Q58FF7|H90B3_HUMAN" 2 1235.6299 0.94 52924 19613 3 1235.629129 412.8839 Heat shock protein HSP 90-beta OS=Homo sapiens OX=9606 GN=HSP90AB1 PE=1 SV=4 6.07 3245.9 - 699187 - - - -0.6013 - 2.207 0.563 - 422.3 1 2 0 -0.0007 10 0 0 0 1.40E+07 1.49E+07 - - - 7.1286 0.9999 221125_WJC_METTL3_EV_vs_WT_F04.19617.19617.3 1.88E-07 17/60 K.FR[166.11]QDLMNIAGTTLSSK[136.11].L "sp|P78371|TCPB_HUMAN,tr|F8VQ14|F8VQ14_HUMAN,tr|F5GWF6|F5GWF6_HUMAN" 3 1798.9366 2.35 52926 19617 3 1798.934511 600.6528 T-complex protein 1 subunit beta OS=Homo sapiens OX=9606 GN=CCT2 PE=1 SV=4 8.75 3246.4 - 8.22E+06 - - - -1.1829 - 2.884 0.623 - 444.9 1 2 1 -0.0021 16 0 0 0 7.61E+08 3.24E+08 - - - 8.203 1 221125_WJC_METTL3_EV_vs_WT_F04.19618.19618.3 3.12E-05 23/80 R.VAILVDDMADTC[160.03]GTIC[160.03]HAADK[136.11].L "sp|P60891|PRPS1_HUMAN,sp|P11908|PRPS2_HUMAN,tr|A0A2R8Y7H4|A0A2R8Y7H4_HUMAN,tr|B1ALA9|B1ALA9_HUMAN,tr|A0A6Q8PEU0|A0A6Q8PEU0_HUMAN,tr|A0A6Q8PG82|A0A6Q8PG82_HUMAN" 6 2283.0425 0.9 52927 19618 3 2283.04145 762.0214 Ribose-phosphate pyrophosphokinase 1 OS=Homo sapiens OX=9606 GN=PRPS1 PE=1 SV=2 4.13 3246.4 - 1.54E+06 - - - -0.4551 - 4.756 0.681 - 711.9 1 2 0 -0.001 21 0 0 0 2.23E+07 2.47E+07 - - - 9.8708 0.9982 221125_WJC_METTL3_EV_vs_WT_F04.19621.19621.3 0.000698 Nov-40 R.DKLNNLVLFDK.A sp|P62851|RS25_HUMAN 1 1317.7293 1.65 52930 19621 3 1317.728284 440.2504 40S ribosomal protein S25 OS=Homo sapiens OX=9606 GN=RPS25 PE=1 SV=1 5.96 3246.8 - 718600 - - - -0.7346 - 2.034 0.311 - 264.7 1 2 1 -0.001 11 0 0 0 1.82E+07 1.10E+07 - - - 4.0241 0.9999 221125_WJC_METTL3_EV_vs_WT_F04.19629.19629.3 1.78E-06 16/64 K.VTEGLTDVILYHQPDDK[136.11].K "sp|O60506|HNRPQ_HUMAN,tr|A0A7I2YQV8|A0A7I2YQV8_HUMAN,tr|A0A7I2YQN2|A0A7I2YQN2_HUMAN,tr|A0A7I2V5Q6|A0A7I2V5Q6_HUMAN,tr|A0A7I2V4Z0|A0A7I2V4Z0_HUMAN,tr|B7Z645|B7Z645_HUMAN,tr|A0A7I2V2F2|A0A7I2V2F2_HUMAN,tr|A0A7I2V346|A0A7I2V346_HUMAN,tr|A0A7I2V309|A0A7I2V309_HUMAN" 9 1949.9826 1.39 52935 19629 3 1949.988552 651.0015 Heterogeneous nuclear ribonucleoprotein Q OS=Homo sapiens OX=9606 GN=SYNCRIP PE=1 SV=2 4.22 3247.7 - 1.56E+06 - - - 3.0662 - 3.18 0.541 - 341.9 1 2 0 0.006 17 0 0 0 1.78E+08 1.28E+08 - - - 7.4926 1 221125_WJC_METTL3_EV_vs_WT_F04.19630.19630.3 5.37E-11 21/80 R.VAILVDDMADTC[160.03]GTIC[160.03]HAADK.L "sp|P60891|PRPS1_HUMAN,sp|P11908|PRPS2_HUMAN,tr|A0A2R8Y7H4|A0A2R8Y7H4_HUMAN,tr|B1ALA9|B1ALA9_HUMAN,tr|A0A6Q8PEU0|A0A6Q8PEU0_HUMAN,tr|A0A6Q8PG82|A0A6Q8PG82_HUMAN" 6 2275.0283 0.89 52936 19630 3 2275.02347 759.35 Ribose-phosphate pyrophosphokinase 1 OS=Homo sapiens OX=9606 GN=PRPS1 PE=1 SV=2 4.13 3247.8 - 1.75E+06 - - - -2.1182 - 4.514 0.673 - 531.1 1 2 0 -0.0048 21 0 0 0 2.20E+07 2.47E+07 - - - 9.6554 1 221125_WJC_METTL3_EV_vs_WT_F04.19631.19631.3 2.80E-07 13/60 R.SIIQQHNLETLENDIK.G sp|O00443|P3C2A_HUMAN 1 1893.9796 1.51 52937 19631 3 1893.979708 632.3338 Phosphatidylinositol 4-phosphate 3-kinase C2 domain-containing subunit alpha OS=Homo sapiens OX=9606 GN=PIK3C2A PE=1 SV=2 4.65 3248 - 1.27E+06 - - - 0.0539 - 2.703 0.486 - 129.1 1 2 0 0.0001 16 0 0 0 5.47E+07 3.63E+07 - - - 6.5098 1 221125_WJC_METTL3_EV_vs_WT_F04.19632.19632.3 2.40E-13 19/96 K.TLGEC[160.03]GFTSQTARPQAPATVGLAFR.A "sp|Q15370|ELOB_HUMAN,tr|I3L0M9|I3L0M9_HUMAN,tr|B8ZZU8|B8ZZU8_HUMAN" 3 2635.3177 0.79 52938 19632 3 2635.314444 879.4465 Elongin-B OS=Homo sapiens OX=9606 GN=ELOB PE=1 SV=1 7.91 3248.1 - 1.14E+06 - - - -1.2241 - 3.586 0.694 - 249.3 1 2 0 -0.0032 25 0 0 0 1.75E+07 2.21E+07 - - - 9.2145 0.9997 221125_WJC_METTL3_EV_vs_WT_F04.19633.19633.3 0.000116 Dec-40 R.DK[136.11]LNNLVLFDK[136.11].A sp|P62851|RS25_HUMAN 1 1333.7577 1.62 52939 19633 3 1333.75649 445.5932 40S ribosomal protein S25 OS=Homo sapiens OX=9606 GN=RPS25 PE=1 SV=1 5.96 3248.2 - 908859 - - - -0.8712 - 2.097 0.444 - 220.2 1 2 1 -0.0012 11 0 0 0 1.76E+07 1.09E+07 - - - 5.5935 1 221125_WJC_METTL3_EV_vs_WT_F04.19634.19634.2 1.01E-11 18/32 K.FNVTGTPEQYVPYSTTR.K sp|Q9UI09|NDUAC_HUMAN 1 1958.9374 1.14 52940 19634 2 1958.93389 980.476 NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 12 OS=Homo sapiens OX=9606 GN=NDUFA12 PE=1 SV=1 6 3248.4 - 802153 - - - -1.7954 - 3.222 0.639 - 860 1 2 0 -0.0035 17 0 0 0 1.20E+07 1.06E+07 - - - 6.6361 0.9994 221125_WJC_METTL3_EV_vs_WT_F04.19637.19637.3 6.66E-06 15/44 R.ENLISALEEAK[136.11]K[136.11].G sp|P22102|PUR2_HUMAN 1 1359.758 0.85 52943 19637 3 1359.750521 454.26 Trifunctional purine biosynthetic protein adenosine-3 OS=Homo sapiens OX=9606 GN=GART PE=1 SV=1 4.79 3248.7 - 720487 - - - -5.5341 - 3.032 0.464 - 477.9 1 2 0 -0.0075 12 0 0 0 1.68E+07 1.98E+07 - - - 6.7857 0.9995 221125_WJC_METTL3_EV_vs_WT_F04.19638.19638.2 2.69E-09 16/28 R.ANQLAEEIESSAQYK.A "sp|Q99700|ATX2_HUMAN,tr|F8W0B5|F8W0B5_HUMAN,tr|A0A5F9ZHW5|A0A5F9ZHW5_HUMAN,tr|A0A5F9ZHH4|A0A5F9ZHH4_HUMAN,tr|A0A5F9ZI57|A0A5F9ZI57_HUMAN,tr|A0A2R8YDM9|A0A2R8YDM9_HUMAN,tr|F8VQP2|F8VQP2_HUMAN,tr|A0A2R8Y5A6|A0A2R8Y5A6_HUMAN,tr|F8WB06|F8WB06_HUMAN,tr|A0A5F9ZH85|A0A5F9ZH85_HUMAN,tr|F8VRK6|F8VRK6_HUMAN,tr|V9GY86|V9GY86_HUMAN,tr|A0A2R8Y7E6|A0A2R8Y7E6_HUMAN,tr|A0A5F9ZHX3|A0A5F9ZHX3_HUMAN,tr|H0YH87|H0YH87_HUMAN,tr|A0A2R8Y7P6|A0A2R8Y7P6_HUMAN" 16 1679.8002 0.88 52944 19638 2 1679.805686 840.9074 Ataxin-2 OS=Homo sapiens OX=9606 GN=ATXN2 PE=1 SV=2 4.25 3248.9 - 650126 - - - 3.2391 - 3.276 0.503 - 967.4 1 2 0 0.0054 15 0 0 0 6.36E+06 7.25E+06 - - - 5.6718 0.9999 221125_WJC_METTL3_EV_vs_WT_F04.19640.19640.2 0.000112 18-Nov K.FAAQELIEVK[136.11].R "sp|Q86U44|MTA70_HUMAN,tr|F5H6D8|F5H6D8_HUMAN,tr|H0YFV6|H0YFV6_HUMAN,tr|B4DTN4|B4DTN4_HUMAN" 4 1154.6427 0.02 52945 19640 2 1154.642481 578.3286 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 4.53 3249.1 - 5.79E+07 - - - -0.168 - 2.072 0.463 - 327.6 1 2 0 -0.0002 10 0 0 0 2.10E+07 9.29E+08 - - - 4.4942 1 221125_WJC_METTL3_EV_vs_WT_F04.19642.19642.3 4.39E-07 20/64 K.VTEGLTDVILYHQPDDK.K "sp|O60506|HNRPQ_HUMAN,tr|A0A7I2YQV8|A0A7I2YQV8_HUMAN,tr|A0A7I2YQN2|A0A7I2YQN2_HUMAN,tr|A0A7I2V5Q6|A0A7I2V5Q6_HUMAN,tr|A0A7I2V4Z0|A0A7I2V4Z0_HUMAN,tr|B7Z645|B7Z645_HUMAN,tr|A0A7I2V2F2|A0A7I2V2F2_HUMAN,tr|A0A7I2V346|A0A7I2V346_HUMAN,tr|A0A7I2V309|A0A7I2V309_HUMAN" 9 1941.9684 1.38 52947 19642 3 1941.966672 648.3301 Heterogeneous nuclear ribonucleoprotein Q OS=Homo sapiens OX=9606 GN=SYNCRIP PE=1 SV=2 4.22 3249.2 - 5.05E+06 - - - -0.8759 - 3.683 0.469 - 571.5 1 2 0 -0.0017 17 0 0 0 1.77E+08 1.28E+08 - - - 7.062 1 221125_WJC_METTL3_EV_vs_WT_F04.19643.19643.2 1.09E-13 18/32 K.TDMDNQIVVSDYAQMDR[166.11].V sp|P50991|TCPD_HUMAN 1 2009.8698 0.22 52948 19643 2 2009.866951 1005.9422 T-complex protein 1 subunit delta OS=Homo sapiens OX=9606 GN=CCT4 PE=1 SV=4 3.77 3249.3 - 4.14E+06 - - - -1.423 - 3.725 0.73 - 898.9 1 2 0 -0.0029 17 0 0 0 1.03E+07 4.74E+07 - - - 7.665 1 221125_WJC_METTL3_EV_vs_WT_F04.19644.19644.4 1.52E-11 25/144 K.IVPAHVPTPIQPTFGGATHSAFGLK.A "sp|A6NF01|P121B_HUMAN,sp|A8CG34|P121C_HUMAN" 2 2542.3696 2.01 52949 19644 4 2542.366814 636.5997 Putative nuclear envelope pore membrane protein POM 121B OS=Homo sapiens OX=9606 GN=POM121B PE=5 SV=2 8.76 3249.4 - 2.51E+06 - - - -1.1072 - 3.898 0.603 - 301 1 2 0 -0.0028 25 0 0 0 1.85E+07 9.22E+06 - - - 4.9065 1 221125_WJC_METTL3_EV_vs_WT_F04.19647.19647.2 2.02E-09 22/30 K.FR[166.11]QDLMNIAGTTLSSK[136.11].L "sp|P78371|TCPB_HUMAN,tr|F8VQ14|F8VQ14_HUMAN,tr|F5GWF6|F5GWF6_HUMAN" 3 1798.9366 0.001 52952 19647 2 1798.934575 900.4756 T-complex protein 1 subunit beta OS=Homo sapiens OX=9606 GN=CCT2 PE=1 SV=4 8.75 3249.6 - 1.95E+06 - - - -1.1473 - 4.562 0.588 - 1208.1 1 2 1 -0.0021 16 0 0 0 0.00E+00 2.16E+07 - - - 7.1148 1 221125_WJC_METTL3_EV_vs_WT_F04.19648.19648.4 8.08E-12 28/120 R.ISLVLGGDHSLAIGSISGHAR.V "sp|P05089|ARGI1_HUMAN,tr|A0A5F9ZGN6|A0A5F9ZGN6_HUMAN" 2 2059.1174 39.39 52953 19648 4 2059.118154 515.7866 Arginase-1 OS=Homo sapiens OX=9606 GN=ARG1 PE=1 SV=2 6.92 3249.7 - 1.69E+06 - - - 0.3482 - 3.755 0.626 - 590.2 1 2 0 0.0007 21 0 0 0 3.11E+07 7.89E+05 - - - 5.112 1 221125_WJC_METTL3_EV_vs_WT_F04.19649.19649.2 4.56E-06 16/36 R.TTTVNIGSISTADGSALVK[136.11].L sp|Q96B26|EXOS8_HUMAN 1 1841.9826 1.12 52954 19649 2 1841.983288 921.9986 Exosome complex component RRP43 OS=Homo sapiens OX=9606 GN=EXOSC8 PE=1 SV=1 5.5 3249.8 - 828787 - - - 0.3882 - 3.049 0.572 - 633 1 2 0 0.0007 19 0 0 0 2.16E+07 1.93E+07 - - - 6.0064 0.9898 221125_WJC_METTL3_EV_vs_WT_F04.19650.19650.3 1.02E-08 17/64 R.AFTMDC[160.03]ITLEGDQVSHR[166.11].G sp|Q9UQE7|SMC3_HUMAN 1 1988.896 1.26 52955 19650 3 1989.887571 663.9726 Structural maintenance of chromosomes protein 3 OS=Homo sapiens OX=9606 GN=SMC3 PE=1 SV=2 4.54 3250 - 823766 - - - 498.5706 - 2.94 0.626 - 311.6 1 2 0 0.9916 17 0 0 0 1.42E+07 1.13E+07 - - - 7.969 0.9999 221125_WJC_METTL3_EV_vs_WT_F04.19651.19651.2 3.89E-09 17/36 R.TTTVNIGSISTADGSALVK.L sp|Q96B26|EXOS8_HUMAN 1 1833.9684 1.12 52956 19651 2 1833.967759 917.9915 Exosome complex component RRP43 OS=Homo sapiens OX=9606 GN=EXOSC8 PE=1 SV=1 5.5 3250.1 - 795828 - - - -0.3348 - 3.115 0.488 - 695.3 1 2 0 -0.0006 19 0 0 0 2.16E+07 1.93E+07 - - - 5.4386 1 221125_WJC_METTL3_EV_vs_WT_F04.19660.19660.3 2.27E-09 15/60 R.SIIQQHNLETLENDIK[136.11].G sp|O00443|P3C2A_HUMAN 1 1901.9938 1.45 52963 19660 3 1901.991517 635.0052 Phosphatidylinositol 4-phosphate 3-kinase C2 domain-containing subunit alpha OS=Homo sapiens OX=9606 GN=PIK3C2A PE=1 SV=2 4.65 3251.1 - 3.19E+06 - - - -1.2035 - 3.111 0.628 - 153.6 1 2 0 -0.0023 16 0 0 0 5.25E+07 3.61E+07 - - - 8.4531 0.9996 221125_WJC_METTL3_EV_vs_WT_F04.19664.19664.3 0.00186 Sep-84 R.GPPPSWASEPER[166.11]PSILSASELK[136.11].E "sp|Q9Y520|PRC2C_HUMAN,tr|A0A0A0MS30|A0A0A0MS30_HUMAN,tr|E7EPN9|E7EPN9_HUMAN" 3 2352.208 1.91 52967 19664 3 2352.202897 785.0766 Protein PRRC2C OS=Homo sapiens OX=9606 GN=PRRC2C PE=1 SV=4 4.79 3251.6 - 1.31E+06 - - - -2.189 - 2.18 0.383 - 50.5 2 2 0 -0.0051 22 0 0 0 2.41E+07 1.26E+07 - - - 4.517 0.9995 221125_WJC_METTL3_EV_vs_WT_F04.19665.19665.3 0.000213 14/44 R.ENLISALEEAKK.G sp|P22102|PUR2_HUMAN 1 1343.7296 0.84 52968 19665 3 1343.727975 448.9172 Trifunctional purine biosynthetic protein adenosine-3 OS=Homo sapiens OX=9606 GN=GART PE=1 SV=1 4.79 3251.7 - 1.07E+06 - - - -1.2436 - 2.517 0.248 - 438.4 1 2 0 -0.0017 12 0 0 0 1.68E+07 2.01E+07 - - - 3.8631 1 221125_WJC_METTL3_EV_vs_WT_F04.19666.19666.2 9.37E-07 16/26 R.C[160.03]ESGFIEELPEETR.S "sp|Q9BV68|RN126_HUMAN,tr|U3KQF4|U3KQF4_HUMAN,tr|K7EIY6|K7EIY6_HUMAN" 3 1694.7458 0.95 52969 19666 2 1694.745504 848.3802 E3 ubiquitin-protein ligase RNF126 OS=Homo sapiens OX=9606 GN=RNF126 PE=1 SV=2 3.98 3251.9 - 818632 - - - -0.1546 - 3.164 0.625 - 1114.7 1 2 0 -0.0003 14 0 0 0 1.89E+07 2.00E+07 - - - 6.5476 0.9995 221125_WJC_METTL3_EV_vs_WT_F04.19671.19671.3 0.00105 Dec-72 R.TTTVNIGSISTADGSALVK[136.11].L sp|Q96B26|EXOS8_HUMAN 1 1841.9826 1.41 52972 19671 3 1841.978019 615.0015 Exosome complex component RRP43 OS=Homo sapiens OX=9606 GN=EXOSC8 PE=1 SV=1 5.5 3252.4 - 1.15E+06 - - - -2.4723 - 2.333 0.356 - 161.4 1 2 0 -0.0046 19 0 0 0 1.12E+07 7.93E+06 - - - 4.5891 1 221125_WJC_METTL3_EV_vs_WT_F04.19674.19674.3 1.61E-07 17/60 R.NIVQEDHPIMSFTISK.N "sp|Q9H7D7|WDR26_HUMAN,tr|A0A7P0SXD0|A0A7P0SXD0_HUMAN,tr|H0Y9R3|H0Y9R3_HUMAN,tr|A0A7I2YQL3|A0A7I2YQL3_HUMAN,tr|A0A7I2YQQ9|A0A7I2YQQ9_HUMAN,tr|A0A499FIZ0|A0A499FIZ0_HUMAN" 6 1857.9295 1.09 52975 19674 3 1857.92656 620.3171 WD repeat-containing protein 26 OS=Homo sapiens OX=9606 GN=WDR26 PE=1 SV=3 5.32 3252.7 - 1.66E+06 - - - -1.5743 - 2.653 0.5 - 203.8 1 2 0 -0.0029 16 0 0 0 1.40E+07 1.28E+07 - - - 6.6172 1 221125_WJC_METTL3_EV_vs_WT_F04.19675.19675.3 1.32E-07 19/64 R.AFTMDC[160.03]ITLEGDQVSHR.G sp|Q9UQE7|SMC3_HUMAN 1 1978.8877 0.74 52976 19675 3 1978.888584 660.6365 Structural maintenance of chromosomes protein 3 OS=Homo sapiens OX=9606 GN=SMC3 PE=1 SV=2 4.54 3252.8 - 1.19E+06 - - - 0.4487 - 2.773 0.583 - 411.7 1 2 0 0.0009 17 0 0 0 5.87E+06 7.98E+06 - - - 7.6163 1 221125_WJC_METTL3_EV_vs_WT_F04.19677.19677.3 2.34E-08 17/72 R.TMLTNDGSDIHSAVLSTIR[166.11].K sp|P46019|KPB2_HUMAN 1 2040.0185 2.67 52978 19677 3 2040.020365 681.0135 "Phosphorylase b kinase regulatory subunit alpha, liver isoform OS=Homo sapiens OX=9606 GN=PHKA2 PE=1 SV=1" 5.18 3253.1 - 773532 - - - 0.9024 - 3.203 0.617 - 281.3 1 2 0 0.0018 19 0 0 0 1.36E+07 5.10E+06 - - - 8.2784 0.9998 221125_WJC_METTL3_EV_vs_WT_F04.19682.19682.3 2.35E-05 Nov-60 K.YPIEHGIITNWDDMEK[136.11].L "sp|P68133|ACTS_HUMAN,sp|P62736|ACTA_HUMAN,sp|P68032|ACTC_HUMAN,sp|P63267|ACTH_HUMAN,tr|B8ZZJ2|B8ZZJ2_HUMAN,tr|F6QUT6|F6QUT6_HUMAN,tr|F6UVQ4|F6UVQ4_HUMAN,tr|F8WB63|F8WB63_HUMAN,tr|A0A804HKV3|A0A804HKV3_HUMAN,tr|C9JFL5|C9JFL5_HUMAN,tr|A6NL76|A6NL76_HUMAN" 11 1967.9179 1.56 52981 19682 3 1967.914799 656.9799 "Actin, alpha skeletal muscle OS=Homo sapiens OX=9606 GN=ACTA1 PE=1 SV=1" 4.31 3253.7 - 4.30E+06 - - - -1.5575 - 2.316 0.379 - 77.1 1 2 0 -0.0031 16 0 0 0 7.14E+07 4.57E+07 - - - 4.9195 0.9999 221125_WJC_METTL3_EV_vs_WT_F04.19683.19683.3 7.61E-09 15/68 R.KVPGVTAIELGEETC[160.03]TFR.L sp|P51116|FXR2_HUMAN 1 2006.0143 1.16 52982 19683 3 2006.020699 669.6787 Fragile X mental retardation syndrome-related protein 2 OS=Homo sapiens OX=9606 GN=FXR2 PE=1 SV=2 4.79 3253.8 - 1.92E+06 - - - 3.2014 - 2.803 0.548 - 246.7 1 2 0 0.0064 18 0 0 0 2.61E+07 2.24E+07 - - - 7.2144 1 221125_WJC_METTL3_EV_vs_WT_F04.19686.19686.2 1.53E-10 13/34 K.TVDSQGPTPVC[160.03]TPTFLER.R "sp|Q9BYG3|MK67I_HUMAN,tr|C9J808|C9J808_HUMAN,tr|H7BZL0|H7BZL0_HUMAN" 3 2003.9622 1.27 52985 19686 2 2003.960864 1002.9884 MKI67 FHA domain-interacting nucleolar phosphoprotein OS=Homo sapiens OX=9606 GN=NIFK PE=1 SV=1 4.37 3254.2 - 650031 - - - -0.6876 - 2.985 0.631 - 433.4 1 2 0 -0.0014 18 0 0 0 8.22E+06 6.48E+06 - - - 6.3898 0.995 221125_WJC_METTL3_EV_vs_WT_F04.19687.19687.2 9.97E-08 14/26 K.LHEEEIQELQAQIQ.E "sp|P08670|VIME_HUMAN,tr|B0YJC5|B0YJC5_HUMAN,tr|B0YJC4|B0YJC4_HUMAN" 3 1706.8475 - 52986 19687 2 1706.847842 854.431 Vimentin OS=Homo sapiens OX=9606 GN=VIM PE=1 SV=4 4.09 3254.3 - 619262 - - - 0.1834 - 2.885 0.543 - 678.1 1 1 0 0.0003 14 0 0 0 - - - - - 5.7103 0.9929 221125_WJC_METTL3_EV_vs_WT_F04.19688.19688.3 7.14E-05 15/56 K.MQHNVLVAEVTQQLK[136.11].A "sp|Q13618|CUL3_HUMAN,tr|A0A087WTG3|A0A087WTG3_HUMAN" 2 1744.9385 1.85 52987 19688 3 1744.925891 582.6535 Cullin-3 OS=Homo sapiens OX=9606 GN=CUL3 PE=1 SV=2 6.5 3254.4 - 540780 - - - -7.249 - 2.74 0.364 - 416 1 2 0 -0.0126 15 0 0 0 1.16E+07 6.25E+06 - - - 5.2249 1 221125_WJC_METTL3_EV_vs_WT_F04.19690.19690.2 4.33E-08 20/32 K.VTEGLTDVILYHQPDDK.K "sp|O60506|HNRPQ_HUMAN,tr|A0A7I2YQV8|A0A7I2YQV8_HUMAN,tr|A0A7I2YQN2|A0A7I2YQN2_HUMAN,tr|A0A7I2V5Q6|A0A7I2V5Q6_HUMAN,tr|A0A7I2V4Z0|A0A7I2V4Z0_HUMAN,tr|B7Z645|B7Z645_HUMAN,tr|A0A7I2V2F2|A0A7I2V2F2_HUMAN,tr|A0A7I2V346|A0A7I2V346_HUMAN,tr|A0A7I2V309|A0A7I2V309_HUMAN" 9 1941.9684 2.3 52989 19690 2 1941.958027 971.9915 Heterogeneous nuclear ribonucleoprotein Q OS=Homo sapiens OX=9606 GN=SYNCRIP PE=1 SV=2 4.22 3254.7 - 427574 - - - -5.3276 - 3.52 0.653 - 1126.9 1 2 0 -0.0103 17 0 0 0 5.66E+06 2.46E+06 - - - 6.9548 1 221125_WJC_METTL3_EV_vs_WT_F04.19695.19695.3 2.45E-10 19/88 K.AELLDNEK[136.11]PAAVVAPITTGYTVK[136.11].L sp|Q9HB71|CYBP_HUMAN 1 2415.3232 0.48 52992 19695 3 2415.322026 806.115 Calcyclin-binding protein OS=Homo sapiens OX=9606 GN=CACYBP PE=1 SV=2 4.68 3255.3 - 1.80E+06 - - - -0.4828 - 3.137 0.578 - 210.3 1 2 0 -0.0012 23 0 0 0 7.30E+06 1.53E+07 - - - 7.6658 1 221125_WJC_METTL3_EV_vs_WT_F04.19696.19696.3 4.32E-15 21/72 K.C[160.03]NLHMNGNVITSDQPILLR.L "sp|Q9BY77|PDIP3_HUMAN,tr|F6VRR5|F6VRR5_HUMAN" 2 2194.0987 1.35 52993 19696 3 2194.09637 732.3735 Polymerase delta-interacting protein 3 OS=Homo sapiens OX=9606 GN=POLDIP3 PE=1 SV=2 6.74 3255.4 - 3.43E+06 - - - -1.0583 - 4.167 0.747 - 622.1 1 2 0 -0.0023 19 0 0 0 3.64E+08 2.70E+08 - - - 10.374 1 221125_WJC_METTL3_EV_vs_WT_F04.19697.19697.3 1.82E-06 16/44 K.GTNYLADVFEKK.D sp|P31151|S10A7_HUMAN 1 1383.7034 13.54 52994 19697 3 1383.702036 462.2418 Protein S100-A7 OS=Homo sapiens OX=9606 GN=S100A7 PE=1 SV=4 6.07 3255.4 - 2.27E+06 - - - -1.0082 - 2.699 0.535 - 468.4 1 2 0 -0.0014 12 0 0 0 7.92E+07 5.85E+06 - - - 7.2565 1 221125_WJC_METTL3_EV_vs_WT_F04.19698.19698.2 4.27E-08 14/24 K.DC[160.03]NSAEAMDDFMK.R "sp|Q16875|F263_HUMAN,tr|A0A1W2PR17|A0A1W2PR17_HUMAN,tr|Q5W015|Q5W015_HUMAN,tr|F2Z2I2|F2Z2I2_HUMAN,tr|Q5VX20|Q5VX20_HUMAN" 5 1532.5582 5.49 52995 19698 2 1532.557613 767.2864 "6-phosphofructo-2-kinase\fructose-2,6-bisphosphatase 3 OS=Homo sapiens OX=9606 GN=PFKFB3 PE=1 SV=1" 3.84 3255.6 - 1.32E+06 - - - -0.3602 - 2.948 0.8 - 799.9 1 2 0 -0.0006 13 0 0 0 1.78E+07 3.24E+06 - - - 7.7244 0.9987 221125_WJC_METTL3_EV_vs_WT_F04.19699.19699.3 1.42E-09 14/56 A.SFNDTFVHVTDLSGK[136.11].E "sp|P62263|RS14_HUMAN,tr|A0A2R8Y811|A0A2R8Y811_HUMAN,tr|E5RH77|E5RH77_HUMAN" 3 1673.8141 1.27 52996 19699 3 1673.813497 558.9453 40S ribosomal protein S14 OS=Homo sapiens OX=9606 GN=RPS14 PE=1 SV=3 5.19 3255.7 - 1.22E+06 - - - -0.331 - 2.849 0.586 - 157.4 1 1 0 -0.0006 15 0 0 0 3.14E+07 2.48E+07 - - - 7.8051 0.9999 221125_WJC_METTL3_EV_vs_WT_F04.19700.19700.3 7.05E-05 Nov-40 K.DLFDYSPPLHK.N "sp|Q9NYF8|BCLF1_HUMAN,tr|E9PKI6|E9PKI6_HUMAN,tr|A0A1W2PQ43|A0A1W2PQ43_HUMAN,tr|E9PK91|E9PK91_HUMAN,tr|E9PK09|E9PK09_HUMAN,tr|E9PQN2|E9PQN2_HUMAN" 6 1330.6558 1.91 52997 19700 3 1330.65467 444.5592 Bcl-2-associated transcription factor 1 OS=Homo sapiens OX=9606 GN=BCLAF1 PE=1 SV=2 5.21 3255.8 - 1.20E+06 - - - -0.8131 - 1.818 0.429 - 129 1 2 0 -0.0011 11 0 0 0 2.12E+07 1.11E+07 - - - 5.0207 0.9999 221125_WJC_METTL3_EV_vs_WT_F04.19701.19701.3 1.17E-07 17/56 K.DVAIKEPLVDVVDPK.Q "sp|Q99873|ANM1_HUMAN,tr|E9PQ98|E9PQ98_HUMAN,tr|E9PKG1|E9PKG1_HUMAN,tr|E9PIX6|E9PIX6_HUMAN" 4 1635.9083 2.31 52998 19701 3 1635.908236 546.3101 Protein arginine N-methyltransferase 1 OS=Homo sapiens OX=9606 GN=PRMT1 PE=1 SV=3 4.23 3255.9 - 798623 - - - -0.0624 - 3.031 0.55 - 305.6 1 2 1 -0.0001 15 0 0 0 3.16E+08 1.36E+08 - - - 7.5654 1 221125_WJC_METTL3_EV_vs_WT_F04.19702.19702.2 1.40E-12 17/32 R.TLSADASVNTLPVVVSR.E "sp|Q92615|LAR4B_HUMAN,tr|H0Y641|H0Y641_HUMAN,tr|H0Y4V9|H0Y4V9_HUMAN" 3 1727.9418 1.13 52999 19702 2 1727.943889 864.9782 La-related protein 4B OS=Homo sapiens OX=9606 GN=LARP4B PE=1 SV=3 5.5 3256 - 675020 - - - 1.2298 - 3.467 0.702 - 892.3 1 2 0 0.0021 17 0 0 0 8.42E+06 7.43E+06 - - - 7.282 1 221125_WJC_METTL3_EV_vs_WT_F04.19704.19704.2 1.87E-09 24-Dec K.DC[160.03]NSAEAMDDFMK[136.11].R "sp|Q16875|F263_HUMAN,tr|A0A1W2PR17|A0A1W2PR17_HUMAN,tr|Q5W015|Q5W015_HUMAN,tr|F2Z2I2|F2Z2I2_HUMAN,tr|Q5VX20|Q5VX20_HUMAN" 5 1540.5724 5.49 53001 19704 2 1540.571115 771.2935 "6-phosphofructo-2-kinase\fructose-2,6-bisphosphatase 3 OS=Homo sapiens OX=9606 GN=PFKFB3 PE=1 SV=1" 3.84 3256.3 - 320948 - - - -0.8114 - 2.69 0.759 - 580.8 1 2 0 -0.0013 13 0 0 0 1.78E+07 3.24E+06 - - - 7.1863 0.9989 221125_WJC_METTL3_EV_vs_WT_F04.19707.19707.3 7.92E-07 13/56 A.SFNDTFVHVTDLSGK.E "sp|P62263|RS14_HUMAN,tr|A0A2R8Y811|A0A2R8Y811_HUMAN,tr|E5RH77|E5RH77_HUMAN" 3 1665.7999 1.27 53002 19707 3 1665.798758 556.2739 40S ribosomal protein S14 OS=Homo sapiens OX=9606 GN=RPS14 PE=1 SV=3 5.19 3256.7 - 2.61E+06 - - - -0.6561 - 2.823 0.621 - 142.7 1 1 0 -0.0011 15 0 0 0 3.14E+07 2.48E+07 - - - 8.1712 1 221125_WJC_METTL3_EV_vs_WT_F04.19709.19709.3 2.68E-12 21/96 K.NLDPDPEPPSPDSPTETFAAPAEVR.H "sp|Q9BUA3|SPNDC_HUMAN,tr|H0YGY5|H0YGY5_HUMAN" 2 2648.2242 12.47 53004 19709 3 2648.224889 883.7487 Spindlin interactor and repressor of chromatin-binding protein OS=Homo sapiens OX=9606 GN=SPINDOC PE=1 SV=3 3.71 3256.9 - 1.66E+06 - - - 0.2579 - 3.18 0.66 - 379.8 1 2 0 0.0007 25 0 0 0 1.33E+07 1.06E+06 - - - 8.5597 1 221125_WJC_METTL3_EV_vs_WT_F04.19711.19711.2 1.80E-06 16/30 K.TTYDSSLSSYTVPLEK.D "sp|Q8WWM7|ATX2L_HUMAN,tr|H3BSK9|H3BSK9_HUMAN,tr|H3BUF6|H3BUF6_HUMAN" 3 1789.8622 1.31 53006 19711 2 1789.860273 895.9384 Ataxin-2-like protein OS=Homo sapiens OX=9606 GN=ATXN2L PE=1 SV=2 4.37 3257.1 - 1.33E+06 - - - -1.0632 - 3.074 0.602 - 395.3 1 2 0 -0.0019 16 0 0 0 4.32E+07 3.30E+07 - - - 6.2477 1 221125_WJC_METTL3_EV_vs_WT_F04.19712.19712.2 3.89E-14 17/30 K.TTYDSSLSSYTVPLEK[136.11].D "sp|Q8WWM7|ATX2L_HUMAN,tr|H3BSK9|H3BSK9_HUMAN,tr|H3BUF6|H3BUF6_HUMAN" 3 1797.8764 1.31 53007 19712 2 1797.875982 899.9455 Ataxin-2-like protein OS=Homo sapiens OX=9606 GN=ATXN2L PE=1 SV=2 4.37 3257.2 - 1.10E+06 - - - -0.2191 - 3.308 0.698 - 522.6 1 2 0 -0.0004 16 0 0 0 4.32E+07 3.30E+07 - - - 7.1376 1 221125_WJC_METTL3_EV_vs_WT_F04.19713.19713.3 1.05E-09 17/88 K.GVVPLAGTNGETTTQGLDGLSER.C "sp|P04075|ALDOA_HUMAN,tr|H3BR04|H3BR04_HUMAN,tr|H3BMQ8|H3BMQ8_HUMAN,tr|H3BU78|H3BU78_HUMAN,tr|H3BQN4|H3BQN4_HUMAN,tr|H3BUH7|H3BUH7_HUMAN,tr|J3KPS3|J3KPS3_HUMAN,tr|H3BPS8|H3BPS8_HUMAN" 8 2271.1343 1.57 53008 19713 3 2271.13175 758.052 Fructose-bisphosphate aldolase A OS=Homo sapiens OX=9606 GN=ALDOA PE=1 SV=2 4.14 3257.4 - 1.03E+06 - - - -1.1091 - 3.055 0.546 - 137.7 1 2 0 -0.0025 23 0 0 0 3.70E+07 2.36E+07 - - - 7.2466 0.998 221125_WJC_METTL3_EV_vs_WT_F04.19714.19714.3 0.0096 Nov-36 R.EKDLEDLFYK.Y "sp|Q13242|SRSF9_HUMAN,tr|H0YIB4|H0YIB4_HUMAN,tr|S4R3G0|S4R3G0_HUMAN" 3 1298.6394 1.45 53009 19714 3 1298.638343 433.8871 Serine\arginine-rich splicing factor 9 OS=Homo sapiens OX=9606 GN=SRSF9 PE=1 SV=1 4.32 3257.5 - 884397 - - - -0.8401 - 1.896 0.317 - 221.6 1 2 1 -0.0011 10 0 0 0 2.64E+07 1.82E+07 - - - 3.9423 0.997 221125_WJC_METTL3_EV_vs_WT_F04.19717.19717.3 0.0429 Sep-40 K.DLFDYSPPLHK[136.11].N "sp|Q9NYF8|BCLF1_HUMAN,tr|E9PKI6|E9PKI6_HUMAN,tr|A0A1W2PQ43|A0A1W2PQ43_HUMAN,tr|E9PK91|E9PK91_HUMAN,tr|E9PK09|E9PK09_HUMAN,tr|E9PQN2|E9PQN2_HUMAN" 6 1338.67 1.91 53012 19717 3 1338.673734 447.2306 Bcl-2-associated transcription factor 1 OS=Homo sapiens OX=9606 GN=BCLAF1 PE=1 SV=2 5.21 3257.8 - 710234 - - - 2.8252 - 1.549 0.324 - 97.1 1 2 0 0.0038 11 0 0 0 2.12E+07 1.10E+07 - - - 3.3944 1 221125_WJC_METTL3_EV_vs_WT_F04.19718.19718.2 4.48E-10 17/32 R.TLSADASVNTLPVVVSR[166.11].E "sp|Q92615|LAR4B_HUMAN,tr|H0Y641|H0Y641_HUMAN,tr|H0Y4V9|H0Y4V9_HUMAN" 3 1737.95 1.13 53013 19718 2 1737.9506 869.9823 La-related protein 4B OS=Homo sapiens OX=9606 GN=LARP4B PE=1 SV=3 5.5 3258 - 656522 - - - 0.3257 - 3.212 0.622 - 494.8 1 2 0 0.0006 17 0 0 0 8.42E+06 7.43E+06 - - - 6.5038 0.9465 221125_WJC_METTL3_EV_vs_WT_F04.19721.19721.2 1.54E-05 24-Dec K.GAVHDVKDVLDSV.L sp|P81605|DCD_HUMAN 1 1352.6936 71.6 53014 19721 2 1352.693644 677.3541 Dermcidin OS=Homo sapiens OX=9606 GN=DCD PE=1 SV=2 4.41 3258.4 - 4.61E+06 - - - 0.0362 - 2.679 0.551 - 384.9 1 1 1 0 13 0 0 0 7.09E+07 9.90E+05 - - - 5.6398 1 221125_WJC_METTL3_EV_vs_WT_F04.19724.19724.3 1.08E-09 17/60 K.VDEFVTHNLSFDEINK.A sp|P11766|ADHX_HUMAN 1 1905.9109 0.36 53017 19724 3 1905.90724 636.3109 Alcohol dehydrogenase class-3 OS=Homo sapiens OX=9606 GN=ADH5 PE=1 SV=4 4.31 3258.6 - 1.28E+06 - - - -1.8983 - 3.35 0.643 - 278.2 1 2 0 -0.0036 16 0 0 0 1.16E+07 3.25E+07 - - - 8.8098 1 221125_WJC_METTL3_EV_vs_WT_F04.19727.19727.3 2.41E-07 20/84 K.TLFLAVQVQNEEGKC[160.03]EVTEVSK.L "sp|O95433|AHSA1_HUMAN,tr|G3V3W9|G3V3W9_HUMAN" 2 2507.2578 1.23 53020 19727 3 2507.258539 836.7599 Activator of 90 kDa heat shock protein ATPase homolog 1 OS=Homo sapiens OX=9606 GN=AHSA1 PE=1 SV=1 4.49 3259 - 980653 - - - 0.3127 - 4.109 0.63 - 350.5 1 2 1 0.0008 22 0 0 0 5.38E+06 4.38E+06 - - - 8.9141 1 221125_WJC_METTL3_EV_vs_WT_F04.19729.19729.3 1.77E-18 25/88 K.VVMALGDYMGASC[160.03]HAC[160.03]IGGTNVR.A "sp|P60842|IF4A1_HUMAN,tr|J3KTB5|J3KTB5_HUMAN,tr|J3KT12|J3KT12_HUMAN,tr|J3QKZ9|J3QKZ9_HUMAN,tr|J3QS69|J3QS69_HUMAN,tr|J3QL43|J3QL43_HUMAN,tr|J3KS25|J3KS25_HUMAN,tr|J3KSZ0|J3KSZ0_HUMAN,tr|J3QLN6|J3QLN6_HUMAN,tr|J3QR64|J3QR64_HUMAN" 10 2438.0963 0.96 53022 19729 3 2438.091457 813.7061 Eukaryotic initiation factor 4A-I OS=Homo sapiens OX=9606 GN=EIF4A1 PE=1 SV=1 6.7 3259.3 - 431957 - - - -1.997 - 4.862 0.771 - 923.1 1 2 0 -0.0049 23 0 0 0 4.00E+06 4.16E+06 - - - 10.8445 1 221125_WJC_METTL3_EV_vs_WT_F04.19730.19730.2 4.56E-07 Nov-34 K.TVDSQGPTPVC[160.03]TPTFLER[166.11].R "sp|Q9BYG3|MK67I_HUMAN,tr|C9J808|C9J808_HUMAN,tr|H7BZL0|H7BZL0_HUMAN" 3 2013.9705 1.27 53023 19730 2 2013.971998 1007.9925 MKI67 FHA domain-interacting nucleolar phosphoprotein OS=Homo sapiens OX=9606 GN=NIFK PE=1 SV=1 4.37 3259.4 - 430030 - - - 0.7378 - 2.448 0.615 - 242.4 1 2 0 0.0015 18 0 0 0 8.22E+06 6.48E+06 - - - 5.784 0.942 221125_WJC_METTL3_EV_vs_WT_F04.19731.19731.3 0.261 Sep-48 K.LK[136.11]EVFSMAGVVVR[166.11].A "sp|P52272|HNRPM_HUMAN,tr|M0R019|M0R019_HUMAN,tr|M0R0N3|M0R0N3_HUMAN,tr|A0A087X0X3|A0A087X0X3_HUMAN,tr|M0QZM1|M0QZM1_HUMAN,tr|M0QYQ7|M0QYQ7_HUMAN,tr|M0R2T0|M0R2T0_HUMAN" 7 1451.8289 1.21 53024 19731 3 1451.82895 484.9503 Heterogeneous nuclear ribonucleoprotein M OS=Homo sapiens OX=9606 GN=HNRNPM PE=1 SV=3 8.75 3259.5 - 382414 - - - 0.0165 - 1.685 0.151 - 112.3 1 2 1 0 13 0 0 0 3.10E+06 2.57E+06 - - - 1.6382 1 221125_WJC_METTL3_EV_vs_WT_F04.19739.19739.3 7.64E-12 21/80 R.MVAADNQDTSNLPQLAVPAPR.V "sp|Q8IWZ3|ANKH1_HUMAN,tr|A0A0A0MQZ8|A0A0A0MQZ8_HUMAN,tr|H0Y472|H0Y472_HUMAN,tr|H0Y7Y3|H0Y7Y3_HUMAN,tr|H0Y4P6|H0Y4P6_HUMAN,tr|H7C0V5|H7C0V5_HUMAN,tr|H0Y785|H0Y785_HUMAN" 7 2207.1005 5.65 53030 19739 3 2207.103585 736.7074 Ankyrin repeat and KH domain-containing protein 1 OS=Homo sapiens OX=9606 GN=ANKHD1 PE=1 SV=1 4.21 3260.5 - 4.20E+06 - - - 1.4132 - 3.442 0.711 - 447.1 1 2 0 0.0031 21 0 0 0 1.61E+08 2.85E+07 - - - 9.4295 0.9996 221125_WJC_METTL3_EV_vs_WT_F04.19740.19740.3 0.00138 Dec-36 R.EK[136.11]DLEDLFYK[136.11].Y "sp|Q13242|SRSF9_HUMAN,tr|H0YIB4|H0YIB4_HUMAN,tr|S4R3G0|S4R3G0_HUMAN" 3 1314.6678 1.44 53031 19740 3 1314.667802 439.2299 Serine\arginine-rich splicing factor 9 OS=Homo sapiens OX=9606 GN=SRSF9 PE=1 SV=1 4.32 3260.6 - 2.26E+06 - - - -0.0243 - 2.128 0.402 - 276.7 1 2 1 0 10 0 0 0 2.63E+07 1.82E+07 - - - 5.2274 0.9999 221125_WJC_METTL3_EV_vs_WT_F04.19742.19742.3 3.20E-05 17/72 K.DAGEGLLAVQITDPEGKPK.K "sp|P21333|FLNA_HUMAN,tr|Q60FE5|Q60FE5_HUMAN" 2 1937.0106 2.25 53033 19742 3 1937.014936 646.6775 Filamin-A OS=Homo sapiens OX=9606 GN=FLNA PE=1 SV=4 4.32 3260.7 - 1.89E+06 - - - 2.253 - 2.987 0.445 - 270.9 1 2 0 0.0044 19 0 0 0 1.98E+07 8.79E+06 - - - 6.1885 1 221125_WJC_METTL3_EV_vs_WT_F04.19744.19744.3 0.0441 20/72 K.DAGEGLLAVQITDPEGK[136.11]PK[136.11].K "sp|P21333|FLNA_HUMAN,tr|Q60FE5|Q60FE5_HUMAN" 2 1953.039 2.25 53035 19744 3 1953.040793 652.0203 Filamin-A OS=Homo sapiens OX=9606 GN=FLNA PE=1 SV=4 4.32 3261 - 1.29E+06 - - - 0.9324 - 3.377 0.52 - 474.3 1 2 0 0.0018 19 0 0 0 1.98E+07 8.79E+06 - - - 7.3269 1 221125_WJC_METTL3_EV_vs_WT_F04.19745.19745.3 4.94E-07 23/68 R.TQAVFNHTEDYVLLPDER.T sp|Q05048|CSTF1_HUMAN 1 2146.0331 1.03 53036 19745 3 2146.032784 716.3516 Cleavage stimulation factor subunit 1 OS=Homo sapiens OX=9606 GN=CSTF1 PE=1 SV=1 4.31 3261.1 - 997263 - - - -0.1463 - 4.38 0.655 - 578.9 1 2 0 -0.0003 18 0 0 0 1.46E+07 1.42E+07 - - - 9.5205 0.9999 221125_WJC_METTL3_EV_vs_WT_F04.19746.19746.2 1.75E-07 13/34 K.VGINYQPPTVVPGGDLAK[136.11].V "sp|Q9NY65|TBA8_HUMAN,sp|Q6PEY2|TBA3E_HUMAN,sp|P0DPH7|TBA3C_HUMAN,sp|Q71U36|TBA1A_HUMAN,sp|P0DPH8|TBA3D_HUMAN,sp|P68366|TBA4A_HUMAN,sp|P68363|TBA1B_HUMAN,sp|Q9BQE3|TBA1C_HUMAN,tr|A0A1W2PQM2|A0A1W2PQM2_HUMAN,tr|F5H5D3|F5H5D3_HUMAN,tr|C9J2C0|C9J2C0_HUMAN,tr|V9GZ17|V9GZ17_HUMAN,tr|A0A7P0T945|A0A7P0T945_HUMAN" 13 1831.9923 0.71 53037 19746 2 1831.991301 917.0035 Tubulin alpha-8 chain OS=Homo sapiens OX=9606 GN=TUBA8 PE=1 SV=1 5.81 3261.2 - 631865 - - - -0.5721 - 2.279 0.578 - 267.9 1 2 0 -0.001 18 0 0 0 9.65E+06 1.36E+07 - - - 5.335 1 221125_WJC_METTL3_EV_vs_WT_F04.19749.19749.2 9.61E-09 17/34 K.IESSIDEQVQTAADDSLR.S "sp|Q5VT06|CE350_HUMAN,tr|H0Y6Q4|H0Y6Q4_HUMAN" 2 1975.9334 3.6 53040 19749 2 1975.935776 988.974 Centrosome-associated protein 350 OS=Homo sapiens OX=9606 GN=CEP350 PE=1 SV=1 3.77 3261.6 - 277786 - - - 1.1802 - 3.642 0.671 - 1047.4 1 2 0 0.0023 18 0 0 0 2.20E+06 6.12E+05 - - - 7.174 0.9926 221125_WJC_METTL3_EV_vs_WT_F04.19751.19751.2 9.56E-06 28-Nov A.SFNDTFVHVTDLSGK.E "sp|P62263|RS14_HUMAN,tr|A0A2R8Y811|A0A2R8Y811_HUMAN,tr|E5RH77|E5RH77_HUMAN" 3 1665.7999 3.42 53042 19751 2 1665.798397 833.9072 40S ribosomal protein S14 OS=Homo sapiens OX=9606 GN=RPS14 PE=1 SV=3 5.19 3261.9 - 220688 - - - -0.8729 - 2.286 0.54 - 353.9 1 1 0 -0.0015 15 0 0 0 3.99E+06 1.17E+06 - - - 5.0617 0.9996 221125_WJC_METTL3_EV_vs_WT_F04.19755.19755.3 6.30E-06 14/56 K.DVAIK[136.11]EPLVDVVDPK[136.11].Q "sp|Q99873|ANM1_HUMAN,tr|E9PQ98|E9PQ98_HUMAN,tr|E9PKG1|E9PKG1_HUMAN,tr|E9PIX6|E9PIX6_HUMAN" 4 1651.9367 2.31 53044 19755 3 1651.937268 551.6529 Protein arginine N-methyltransferase 1 OS=Homo sapiens OX=9606 GN=PRMT1 PE=1 SV=3 4.23 3262.3 - 5.71E+06 - - - 0.3208 - 2.584 0.391 - 212.3 1 2 1 0.0005 15 0 0 0 3.14E+08 1.36E+08 - - - 5.3763 0.9998 221125_WJC_METTL3_EV_vs_WT_F04.19759.19759.3 0.00107 Dec-44 K.KISLEDIQAFEK.T sp|Q8WXX5|DNJC9_HUMAN 1 1419.7609 2 53048 19759 3 1419.761937 474.2609 DnaJ homolog subfamily C member 9 OS=Homo sapiens OX=9606 GN=DNAJC9 PE=1 SV=1 4.68 3262.6 - 1.09E+06 - - - 0.698 - 2.259 0.323 - 243.8 1 2 0 0.001 12 0 0 0 7.86E+06 3.94E+06 - - - 4.3997 1 221125_WJC_METTL3_EV_vs_WT_F04.19760.19760.3 9.38E-06 20/52 R.QQQETLAIQVGDLR.L "sp|P82094|TMF1_HUMAN,tr|F8WF45|F8WF45_HUMAN" 2 1597.8424 1.44 53049 19760 3 1597.844055 533.6214 TATA element modulatory factor OS=Homo sapiens OX=9606 GN=TMF1 PE=1 SV=2 4.37 3262.7 - 964966 - - - 1.0458 - 2.717 0.476 - 483.7 1 2 0 0.0017 14 0 0 0 2.43E+07 1.68E+07 - - - 6.5027 0.9996 221125_WJC_METTL3_EV_vs_WT_F04.19761.19761.3 0.0543 Dec-60 R.GLIVYQLENQPSEFR[166.11]R[166.11].L "sp|P78406|RAE1L_HUMAN,tr|E9PQ57|E9PQ57_HUMAN,tr|E9PPG9|E9PPG9_HUMAN" 3 1968.0332 0.97 53050 19761 3 1968.032185 657.0183 mRNA export factor OS=Homo sapiens OX=9606 GN=RAE1 PE=1 SV=1 6.14 3262.9 - 903853 - - - -0.5157 - 2.398 0.296 - 173.1 1 2 0 -0.001 16 0 0 0 1.41E+07 1.45E+07 - - - 4.084 0.9994 221125_WJC_METTL3_EV_vs_WT_F04.19762.19762.2 0.0406 Dec-32 K.AAPGPGPSTFSFVPPSK[136.11].A "sp|P35658|NU214_HUMAN,tr|A0A494C1F2|A0A494C1F2_HUMAN" 2 1650.8497 2.01 53051 19762 2 1650.850739 826.4321 Nuclear pore complex protein Nup214 OS=Homo sapiens OX=9606 GN=NUP214 PE=1 SV=2 8.8 3263 - 772945 - - - 0.6245 - 1.961 0.315 - 178 1 2 0 0.001 17 0 0 0 5.41E+07 2.70E+07 - - - 3.023 0.9999 221125_WJC_METTL3_EV_vs_WT_F04.19763.19763.3 1.52E-06 17/52 R.QQQETLAIQVGDLR[166.11].L "sp|P82094|TMF1_HUMAN,tr|F8WF45|F8WF45_HUMAN" 2 1607.8507 1.44 53052 19763 3 1607.849831 536.9575 TATA element modulatory factor OS=Homo sapiens OX=9606 GN=TMF1 PE=1 SV=2 4.37 3263.1 - 742249 - - - -0.5119 - 2.45 0.362 - 342.4 1 2 0 -0.0008 14 0 0 0 2.43E+07 1.68E+07 - - - 4.9571 0.9999 221125_WJC_METTL3_EV_vs_WT_F04.19765.19765.2 7.01E-06 15/34 K.VGINYQPPTVVPGGDLAK.V "sp|Q9NY65|TBA8_HUMAN,sp|Q6PEY2|TBA3E_HUMAN,sp|P0DPH7|TBA3C_HUMAN,sp|Q71U36|TBA1A_HUMAN,sp|P0DPH8|TBA3D_HUMAN,sp|P68366|TBA4A_HUMAN,sp|P68363|TBA1B_HUMAN,sp|Q9BQE3|TBA1C_HUMAN,tr|A0A1W2PQM2|A0A1W2PQM2_HUMAN,tr|F5H5D3|F5H5D3_HUMAN,tr|C9J2C0|C9J2C0_HUMAN,tr|V9GZ17|V9GZ17_HUMAN,tr|A0A7P0T945|A0A7P0T945_HUMAN" 13 1823.9781 0.71 53054 19765 2 1823.97809 912.9964 Tubulin alpha-8 chain OS=Homo sapiens OX=9606 GN=TUBA8 PE=1 SV=1 5.81 3263.4 - 650434 - - - -0.0323 - 2.422 0.587 - 389.4 1 2 0 -0.0001 18 0 0 0 9.65E+06 1.36E+07 - - - 5.5514 0.9997 221125_WJC_METTL3_EV_vs_WT_F04.19768.19768.3 9.86E-06 16/68 K.VGINYQPPTVVPGGDLAK.V "sp|Q9NY65|TBA8_HUMAN,sp|Q6PEY2|TBA3E_HUMAN,sp|P0DPH7|TBA3C_HUMAN,sp|Q71U36|TBA1A_HUMAN,sp|P0DPH8|TBA3D_HUMAN,sp|P68366|TBA4A_HUMAN,sp|P68363|TBA1B_HUMAN,sp|Q9BQE3|TBA1C_HUMAN,tr|A0A1W2PQM2|A0A1W2PQM2_HUMAN,tr|F5H5D3|F5H5D3_HUMAN,tr|C9J2C0|C9J2C0_HUMAN,tr|V9GZ17|V9GZ17_HUMAN,tr|A0A7P0T945|A0A7P0T945_HUMAN" 13 1823.9781 0.37 53057 19768 3 1823.983317 609 Tubulin alpha-8 chain OS=Homo sapiens OX=9606 GN=TUBA8 PE=1 SV=1 5.81 3263.7 - 577635 - - - 2.8334 - 2.727 0.397 - 219.2 1 2 0 0.0052 18 0 0 0 5.56E+06 1.51E+07 - - - 5.4628 0.9997 221125_WJC_METTL3_EV_vs_WT_F04.19769.19769.3 0.0014 Dec-44 K.K[136.11]ISLEDIQAFEK[136.11].T sp|Q8WXX5|DNJC9_HUMAN 1 1435.7893 1.87 53058 19769 3 1435.789438 479.6037 DnaJ homolog subfamily C member 9 OS=Homo sapiens OX=9606 GN=DNAJC9 PE=1 SV=1 4.68 3263.9 - 526080 - - - 0.0641 - 2.231 0.305 - 199.7 1 2 0 0.0001 12 0 0 0 7.36E+06 3.94E+06 - - - 4.1647 0.9997 221125_WJC_METTL3_EV_vs_WT_F04.19771.19771.2 3.17E-05 22-Nov K.DAGQISGLNVLR[166.11].V "sp|P38646|GRP75_HUMAN,tr|H0Y8K0|H0Y8K0_HUMAN,tr|A0A7I2V2S7|A0A7I2V2S7_HUMAN,tr|A0A7I2V2G2|A0A7I2V2G2_HUMAN,tr|A0A7I2V3F7|A0A7I2V3F7_HUMAN,tr|A0A7I2YQB2|A0A7I2YQB2_HUMAN,tr|D6RCD7|D6RCD7_HUMAN" 7 1251.6811 0.56 53060 19771 2 1251.683029 626.8478 "Stress-70 protein, mitochondrial OS=Homo sapiens OX=9606 GN=HSPA9 PE=1 SV=2" 5.84 3264.1 - 463149 - - - 1.5651 - 2.525 0.418 - 333 1 2 0 0.002 12 0 0 0 7.06E+06 1.27E+07 - - - 4.5648 0.9983 221125_WJC_METTL3_EV_vs_WT_F04.19774.19774.4 2.78E-08 21/96 E.MIGHYLGEFSITYKPVK.H "sp|P62841|RS15_HUMAN,tr|K7EM56|K7EM56_HUMAN,tr|A0A0B4J2B4|A0A0B4J2B4_HUMAN,tr|K7ELC2|K7ELC2_HUMAN,tr|K7EQJ5|K7EQJ5_HUMAN,tr|S4R417|S4R417_HUMAN" 6 1982.0336 1.21 53063 19774 4 1982.034147 496.5157 40S ribosomal protein S15 OS=Homo sapiens OX=9606 GN=RPS15 PE=1 SV=2 8.21 3264.5 - 344242 - - - 0.2982 - 3.411 0.594 - 282.9 1 1 0 0.0006 17 0 0 0 1.62E+07 1.34E+07 - - - 4.822 1 221125_WJC_METTL3_EV_vs_WT_F04.19777.19777.3 1.35E-07 Dec-56 R.EQLDPDELETITMHK[136.11].L sp|Q9NYU2|UGGG1_HUMAN 1 1805.8597 0.13 53064 19777 3 1805.860619 602.9605 UDP-glucose:glycoprotein glucosyltransferase 1 OS=Homo sapiens OX=9606 GN=UGGT1 PE=1 SV=3 4.17 3264.9 - 2.22E+06 - - - 0.52 - 2.548 0.618 - 214.6 1 2 0 0.0009 15 0 0 0 3.00E+06 2.32E+07 - - - 7.8704 1 221125_WJC_METTL3_EV_vs_WT_F04.19779.19779.3 2.37E-05 13/64 R.IINEPTAAAIAYGLDK[136.11]R[166.11].E "sp|P11021|BIP_HUMAN,tr|A0A7P0TB36|A0A7P0TB36_HUMAN,tr|A0A7P0TAI0|A0A7P0TAI0_HUMAN" 3 1833.0115 0.23 53066 19779 3 1833.008333 612.0111 Endoplasmic reticulum chaperone BiP OS=Homo sapiens OX=9606 GN=HSPA5 PE=1 SV=2 6.07 3265 - 1.69E+06 - - - -1.7376 - 2.669 0.483 - 220.2 1 2 0 -0.0032 17 0 0 0 4.74E+06 2.07E+07 - - - 6.4042 0.9998 221125_WJC_METTL3_EV_vs_WT_F04.19780.19780.3 8.76E-06 17/64 K.AAPGPGPSTFSFVPPSK.A "sp|P35658|NU214_HUMAN,tr|A0A494C1F2|A0A494C1F2_HUMAN" 2 1642.8355 0.76 53067 19780 3 1642.839594 548.6191 Nuclear pore complex protein Nup214 OS=Homo sapiens OX=9606 GN=NUP214 PE=1 SV=2 8.8 3265.1 - 1.46E+06 - - - 2.4872 - 2.514 0.418 - 204.9 1 2 0 0.0041 17 0 0 0 2.55E+07 3.38E+07 - - - 5.5281 0.9993 221125_WJC_METTL3_EV_vs_WT_F04.19781.19781.3 0.149 Dec-60 R.GLIVYQLENQPSEFRR.L "sp|P78406|RAE1L_HUMAN,tr|E9PQ57|E9PQ57_HUMAN,tr|E9PPG9|E9PPG9_HUMAN" 3 1948.0167 0.96 53068 19781 3 1948.020099 650.3462 mRNA export factor OS=Homo sapiens OX=9606 GN=RAE1 PE=1 SV=1 6.14 3265.2 - 1.45E+06 - - - 1.7654 - 2.331 0.296 - 165.9 1 2 0 0.0034 16 0 0 0 1.39E+07 1.44E+07 - - - 4.0106 1 221125_WJC_METTL3_EV_vs_WT_F04.19782.19782.2 2.03E-08 16/28 K.DVAIKEPLVDVVDPK.Q "sp|Q99873|ANM1_HUMAN,tr|E9PQ98|E9PQ98_HUMAN,tr|E9PKG1|E9PKG1_HUMAN,tr|E9PIX6|E9PIX6_HUMAN" 4 1635.9083 2.35 53069 19782 2 1635.908844 818.9614 Protein arginine N-methyltransferase 1 OS=Homo sapiens OX=9606 GN=PRMT1 PE=1 SV=3 4.23 3265.3 - 1.44E+06 - - - 0.3093 - 3.461 0.588 - 592.6 1 2 1 0.0005 15 0 0 0 2.75E+07 1.17E+07 - - - 6.4362 1 221125_WJC_METTL3_EV_vs_WT_F04.19784.19784.3 6.34E-06 14/60 K.IYGADDIELLPEAQHK[136.11].A "sp|P11586|C1TC_HUMAN,tr|F5H2F4|F5H2F4_HUMAN,tr|V9GZ78|V9GZ78_HUMAN,tr|V9GYY3|V9GYY3_HUMAN" 4 1818.9243 1.59 53071 19784 3 1818.925502 607.3154 "C-1-tetrahydrofolate synthase, cytoplasmic OS=Homo sapiens OX=9606 GN=MTHFD1 PE=1 SV=4" 4.31 3265.5 - 871609 - - - 0.6449 - 2.639 0.517 - 191.8 1 2 0 0.0012 16 0 0 0 3.96E+07 2.49E+07 - - - 6.7936 1 221125_WJC_METTL3_EV_vs_WT_F04.19786.19786.3 7.12E-06 15/52 R.K[136.11]GDNLQPVTLILSK[136.11].E "sp|Q5VWN6|TASO2_HUMAN,tr|A0A2R8YH03|A0A2R8YH03_HUMAN" 2 1540.9159 1.6 53073 19786 3 1540.917302 514.6459 Protein TASOR 2 OS=Homo sapiens OX=9606 GN=TASOR2 PE=1 SV=1 8.59 3265.8 - 418353 - - - 0.8819 - 2.639 0.504 - 225.5 1 2 0 0.0014 14 0 0 0 7.07E+06 4.42E+06 - - - 6.7376 0.8342 221125_WJC_METTL3_EV_vs_WT_F04.19787.19787.3 3.22E-10 17/64 E.MIGHYLGEFSITYK[136.11]PVK[136.11].H "sp|P62841|RS15_HUMAN,tr|K7EM56|K7EM56_HUMAN,tr|A0A0B4J2B4|A0A0B4J2B4_HUMAN,tr|K7ELC2|K7ELC2_HUMAN,tr|K7EQJ5|K7EQJ5_HUMAN,tr|S4R417|S4R417_HUMAN" 6 1998.062 1.26 53074 19787 3 1998.07727 667.0279 40S ribosomal protein S15 OS=Homo sapiens OX=9606 GN=RPS15 PE=1 SV=2 8.21 3265.9 - 403749 - - - 7.6644 - 2.92 0.499 - 391.5 1 1 0 0.0153 17 0 0 0 6.47E+06 5.11E+06 - - - 6.8063 1 221125_WJC_METTL3_EV_vs_WT_F04.19792.19792.2 1.84E-08 14/26 R.QQQETLAIQVGDLR[166.11].L "sp|P82094|TMF1_HUMAN,tr|F8WF45|F8WF45_HUMAN" 2 1607.8507 1.53 53078 19792 2 1607.850901 804.9326 TATA element modulatory factor OS=Homo sapiens OX=9606 GN=TMF1 PE=1 SV=2 4.37 3266.6 - 1.78E+06 - - - 0.1536 - 3.027 0.63 - 707.1 1 2 0 0.0002 14 0 0 0 3.31E+07 2.15E+07 - - - 6.4735 0.9997 221125_WJC_METTL3_EV_vs_WT_F04.19796.19796.2 0.000244 14/32 K.AAPGPGPSTFSFVPPSK.A "sp|P35658|NU214_HUMAN,tr|A0A494C1F2|A0A494C1F2_HUMAN" 2 1642.8355 2.07 53081 19796 2 1642.838517 822.425 Nuclear pore complex protein Nup214 OS=Homo sapiens OX=9606 GN=NUP214 PE=1 SV=2 8.8 3266.9 - 3.05E+06 - - - 1.8316 - 2.049 0.482 - 209.4 1 2 0 0.003 17 0 0 0 5.27E+07 2.55E+07 - - - 4.3637 0.985 221125_WJC_METTL3_EV_vs_WT_F04.19797.19797.4 4.02E-07 14/96 E.MIGHYLGEFSITYK[136.11]PVK[136.11].H "sp|P62841|RS15_HUMAN,tr|K7EM56|K7EM56_HUMAN,tr|A0A0B4J2B4|A0A0B4J2B4_HUMAN,tr|K7ELC2|K7ELC2_HUMAN,tr|K7EQJ5|K7EQJ5_HUMAN,tr|S4R417|S4R417_HUMAN" 6 1998.062 1.21 53082 19797 4 1998.064716 500.5228 40S ribosomal protein S15 OS=Homo sapiens OX=9606 GN=RPS15 PE=1 SV=2 8.21 3267 - 1.79E+06 - - - 1.3813 - 2.784 0.405 - 148.3 1 1 0 0.0028 17 0 0 0 1.62E+07 1.34E+07 - - - 3.1058 0.9999 221125_WJC_METTL3_EV_vs_WT_F04.19802.19802.4 1.70E-05 15/90 K.DLLPYGFAIHHAGMTR.V "sp|O75643|U520_HUMAN,tr|A0A494C1A5|A0A494C1A5_HUMAN" 2 1797.8985 1.73 53087 19802 4 1797.900893 450.4819 U5 small nuclear ribonucleoprotein 200 kDa helicase OS=Homo sapiens OX=9606 GN=SNRNP200 PE=1 SV=2 6.92 3267.4 - 818131 - - - 1.3538 - 2.902 0.423 - 158.9 1 2 0 0.0024 16 0 0 0 6.41E+06 3.70E+06 - - - 3.2824 0.9953 221125_WJC_METTL3_EV_vs_WT_F04.19803.19803.3 6.64E-09 16/64 E.MIGHYLGEFSITYKPVK.H "sp|P62841|RS15_HUMAN,tr|K7EM56|K7EM56_HUMAN,tr|A0A0B4J2B4|A0A0B4J2B4_HUMAN,tr|K7ELC2|K7ELC2_HUMAN,tr|K7EQJ5|K7EQJ5_HUMAN,tr|S4R417|S4R417_HUMAN" 6 1982.0336 1.26 53088 19803 3 1982.037514 661.6851 40S ribosomal protein S15 OS=Homo sapiens OX=9606 GN=RPS15 PE=1 SV=2 8.21 3267.6 - 776836 - - - 1.9969 - 2.762 0.515 - 292 1 1 0 0.004 17 0 0 0 6.47E+06 5.11E+06 - - - 6.8473 0.9941 221125_WJC_METTL3_EV_vs_WT_F04.19807.19807.3 0.000103 15/44 K.ETSYGLSFFKPR.P sp|Q9Y512|SAM50_HUMAN 1 1430.7194 1.41 53092 19807 3 1430.715691 477.9137 Sorting and assembly machinery component 50 homolog OS=Homo sapiens OX=9606 GN=SAMM50 PE=1 SV=3 8.69 3268.1 - 558045 - - - -2.6029 - 2.763 0.51 - 410.4 1 1 0 -0.0037 12 0 0 0 3.65E+06 2.58E+06 - - - 7.042 0.9236 221125_WJC_METTL3_EV_vs_WT_F04.19808.19808.3 0.277 Sep-60 R.AYFDLQTHVIQVPQGK[136.11].Y "sp|Q8WUB8|PHF10_HUMAN,tr|S5FZ81|S5FZ81_HUMAN" 2 1850.977 1.01 53093 19808 3 1850.975788 617.9996 PHD finger protein 10 OS=Homo sapiens OX=9606 GN=PHF10 PE=1 SV=3 6.79 3268.2 - 401238 - - - -0.6732 - 1.352 0.116 - 39.4 1 2 0 -0.0012 16 0 0 0 9.61E+06 9.56E+06 - - - 0.6068 1 221125_WJC_METTL3_EV_vs_WT_F04.19809.19809.2 1.17E-10 13/34 R.EEGAPGDPEAALEDNLAR.L sp|P33908|MA1A1_HUMAN 1 1852.8439 1.71 53094 19809 2 1852.842332 927.4292 "Mannosyl-oligosaccharide 1,2-alpha-mannosidase IA OS=Homo sapiens OX=9606 GN=MAN1A1 PE=1 SV=3" 3.77 3268.3 - 205234 - - - -0.8463 - 2.466 0.738 - 367 1 2 0 -0.0016 18 0 0 0 2.30E+06 1.35E+06 - - - 6.7105 0.9989 221125_WJC_METTL3_EV_vs_WT_F04.19811.19811.3 5.74E-06 14/88 K.GVVPLAGTNGETTTQGLDGLSER[166.11].C "sp|P04075|ALDOA_HUMAN,tr|H3BR04|H3BR04_HUMAN,tr|H3BMQ8|H3BMQ8_HUMAN,tr|H3BU78|H3BU78_HUMAN,tr|H3BQN4|H3BQN4_HUMAN,tr|H3BUH7|H3BUH7_HUMAN,tr|J3KPS3|J3KPS3_HUMAN,tr|H3BPS8|H3BPS8_HUMAN" 8 2281.1425 1.66 53095 19811 3 2281.152622 761.3881 Fructose-bisphosphate aldolase A OS=Homo sapiens OX=9606 GN=ALDOA PE=1 SV=2 4.14 3268.5 - 307726 - - - 4.4202 - 2.916 0.368 - 227.5 1 2 0 0.0101 23 0 0 0 3.70E+07 2.23E+07 - - - 5.1507 1 221125_WJC_METTL3_EV_vs_WT_F04.19813.19813.2 1.07E-10 15/28 K.QC[160.03]ASLQAAIADAEQR.G sp|P48668|K2C6C_HUMAN 1 1630.7733 999 53096 19813 2 1630.775602 816.3939 "Keratin, type II cytoskeletal 6C OS=Homo sapiens OX=9606 GN=KRT6C PE=1 SV=3" 4.37 3268.7 - 1.98E+06 - - - 1.3999 - 3.448 0.589 - 890.5 1 2 0 0.0023 15 0 0 0 5.64E+07 0.00E+00 - - - 6.4338 0.9999 221125_WJC_METTL3_EV_vs_WT_F04.19814.19814.4 1.40E-06 18/96 K.NLLSEHEQLVVTLEDHK[136.11].S sp|O00461|GOLI4_HUMAN 1 2011.0466 1.79 53097 19814 4 2011.048142 503.7689 Golgi integral membrane protein 4 OS=Homo sapiens OX=9606 GN=GOLIM4 PE=1 SV=1 4.8 3268.9 - 773220 - - - 0.7817 - 2.402 0.468 - 227.4 1 2 0 0.0016 17 0 0 0 1.34E+07 7.47E+06 - - - 3.6033 0.9999 221125_WJC_METTL3_EV_vs_WT_F04.19816.19816.4 7.28E-06 19/90 K.DLLPYGFAIHHAGMTR[166.11].V "sp|O75643|U520_HUMAN,tr|A0A494C1A5|A0A494C1A5_HUMAN" 2 1807.9067 1.77 53099 19816 4 1807.908964 452.984 U5 small nuclear ribonucleoprotein 200 kDa helicase OS=Homo sapiens OX=9606 GN=SNRNP200 PE=1 SV=2 6.92 3269.1 - 476152 - - - 1.2362 - 3.283 0.459 - 246.5 1 2 0 0.0022 16 0 0 0 6.55E+06 3.70E+06 - - - 3.6393 0.9987 221125_WJC_METTL3_EV_vs_WT_F04.19818.19818.3 1.86E-05 13/52 R.IQSLLDIQEKEFEK.F "sp|Q93009|UBP7_HUMAN,tr|A0A669KBL1|A0A669KBL1_HUMAN" 2 1718.9091 1.34 53101 19818 3 1718.911781 573.977 Ubiquitin carboxyl-terminal hydrolase 7 OS=Homo sapiens OX=9606 GN=USP7 PE=1 SV=2 4.41 3269.4 - 360638 - - - 1.5789 - 2.701 0.306 - 180.6 1 2 1 0.0027 14 0 0 0 2.71E+06 2.03E+06 - - - 4.5914 0.9992 221125_WJC_METTL3_EV_vs_WT_F04.19820.19820.3 0.013 Nov-40 R.ELDELKPWIEK.T sp|O43395|PRPF3_HUMAN 1 1398.7395 1.93 53103 19820 3 1398.741206 467.2538 U4\U6 small nuclear ribonucleoprotein Prp3 OS=Homo sapiens OX=9606 GN=PRPF3 PE=1 SV=2 4.41 3269.6 - 290492 - - - 1.2325 - 1.786 0.31 - 146.6 1 2 0 0.0017 11 0 0 0 6.09E+06 3.15E+06 - - - 3.6433 1 221125_WJC_METTL3_EV_vs_WT_F04.19830.19830.3 1.26E-07 16/76 R.GTLSDEHAGVISVLAQQAAK.L "sp|O43504|LTOR5_HUMAN,tr|R4GMU8|R4GMU8_HUMAN,tr|A0A0C4DGV4|A0A0C4DGV4_HUMAN,tr|E9PLX3|E9PLX3_HUMAN" 4 1994.0433 1.16 53111 19830 3 1994.045973 665.6884 Ragulator complex protein LAMTOR5 OS=Homo sapiens OX=9606 GN=LAMTOR5 PE=1 SV=1 5.32 3270.9 - 618501 - - - 1.356 - 3.508 0.554 - 289.4 1 2 0 0.0027 20 0 0 0 5.72E+06 4.93E+06 - - - 7.7606 0.9999 221125_WJC_METTL3_EV_vs_WT_F04.19832.19832.3 1.24E-08 19/72 K.HFPIEIDSTDYVSSGPSVR[166.11].N "sp|P82673|RT35_HUMAN,tr|H0YG82|H0YG82_HUMAN" 2 2115.0148 1.3 53113 19832 3 2115.006798 706.0122 "28S ribosomal protein S35, mitochondrial OS=Homo sapiens OX=9606 GN=MRPS35 PE=1 SV=1" 4.54 3271.2 - 564621 - - - -3.7924 - 3.444 0.611 - 379 1 2 0 -0.008 19 0 0 0 6.70E+06 5.14E+06 - - - 8.388 0.9998 221125_WJC_METTL3_EV_vs_WT_F04.19835.19835.3 5.53E-05 16/60 K.DLLPYGFAIHHAGMTR.V "sp|O75643|U520_HUMAN,tr|A0A494C1A5|A0A494C1A5_HUMAN" 2 1797.8985 0.09 53116 19835 3 1797.903643 600.3068 U5 small nuclear ribonucleoprotein 200 kDa helicase OS=Homo sapiens OX=9606 GN=SNRNP200 PE=1 SV=2 6.92 3271.6 - 678218 - - - 2.8834 - 2.574 0.418 - 267.3 1 2 0 0.0052 16 0 0 0 2.97E+06 3.14E+07 - - - 5.6248 0.9997 221125_WJC_METTL3_EV_vs_WT_F04.19836.19836.3 0.0717 14/44 R.TRLGLEDFESLK.V sp|Q15208|STK38_HUMAN 1 1406.7405 3.58 53117 19836 3 1406.741227 469.9208 Serine\threonine-protein kinase 38 OS=Homo sapiens OX=9606 GN=STK38 PE=1 SV=1 4.68 3271.7 - 455447 - - - 0.4848 - 2.802 0.382 - 344.7 1 2 1 0.0007 12 0 0 0 1.04E+07 2.92E+06 - - - 5.6547 0.9776 221125_WJC_METTL3_EV_vs_WT_F04.19839.19839.3 0.0372 Dec-40 R.ELDELK[136.11]PWIEK[136.11].T sp|O43395|PRPF3_HUMAN 1 1414.7679 2.58 53120 19839 3 1414.770158 472.5966 U4\U6 small nuclear ribonucleoprotein Prp3 OS=Homo sapiens OX=9606 GN=PRPF3 PE=1 SV=2 4.41 3272.1 - 269730 - - - 1.6087 - 1.57 0.157 - 178.9 1 2 0 0.0023 11 0 0 0 5.66E+06 2.19E+06 - - - 1.5712 1 221125_WJC_METTL3_EV_vs_WT_F04.19843.19843.3 2.28E-09 26/68 K.ELQQELQEYEVVTESEKR.D sp|Q96A49|SYAP1_HUMAN 1 2236.0859 1.3 53122 19843 3 2236.088394 746.3693 Synapse-associated protein 1 OS=Homo sapiens OX=9606 GN=SYAP1 PE=1 SV=1 4.21 3272.6 - 9.10E+06 - - - 1.1055 - 4.031 0.522 - 971.3 1 2 0 0.0025 18 0 0 0 1.57E+08 1.20E+08 - - - 7.8303 1 221125_WJC_METTL3_EV_vs_WT_F04.19844.19844.3 4.29E-09 27/68 K.ELQQELQEYEVVTESEK[136.11]R[166.11].D sp|Q96A49|SYAP1_HUMAN 1 2254.1084 1.33 53123 19844 3 2254.10849 752.3767 Synapse-associated protein 1 OS=Homo sapiens OX=9606 GN=SYAP1 PE=1 SV=1 4.21 3272.7 - 7.33E+06 - - - 0.0435 - 4.157 0.628 - 1113.4 1 2 0 0.0001 18 0 0 0 1.52E+08 1.15E+08 - - - 9.0894 0.9981 221125_WJC_METTL3_EV_vs_WT_F04.19848.19848.3 0.315 Nov-44 R.KQVVNIPSFIVR.L sp|P46781|RS9_HUMAN 1 1398.8347 1.06 53127 19848 3 1398.838281 467.2855 40S ribosomal protein S9 OS=Homo sapiens OX=9606 GN=RPS9 PE=1 SV=3 11 3273.1 - 706244 - - - 2.5457 - 2.161 0.261 - 147.9 1 2 0 0.0036 12 0 0 0 1.07E+08 1.00E+08 - - - 3.5848 1 221125_WJC_METTL3_EV_vs_WT_F04.19849.19849.3 9.65E-13 32/72 C.K[136.11]ILGSGISSSSVLHGMVFK[136.11].K sp|P50990|TCPQ_HUMAN 1 1962.0943 0.32 53128 19849 3 1962.093249 655.0387 T-complex protein 1 subunit theta OS=Homo sapiens OX=9606 GN=CCT8 PE=1 SV=4 10 3273.2 - 662127 - - - -0.5453 - 4.94 0.636 - 1088.8 1 1 0 -0.0011 19 0 0 0 2.63E+06 8.18E+06 - - - 9.5549 0.9851 221125_WJC_METTL3_EV_vs_WT_F04.19854.19854.3 0.00312 Aug-80 K.ADC[160.03]PTMEAQTTLTTNDIVISK[136.11].L sp|Q13123|RED_HUMAN 1 2316.1069 0.98 53133 19854 3 2317.105931 773.0429 Protein Red OS=Homo sapiens OX=9606 GN=IK PE=1 SV=3 4.03 3273.9 - 395322 - - - 431.3562 - 2.232 0.37 - 52.7 2 2 0 0.9991 21 0 0 0 2.28E+06 2.32E+06 - - - 4.174 1 221125_WJC_METTL3_EV_vs_WT_F04.19865.19865.3 3.69E-08 18/56 K.QC[160.03]ASLQAAIADAEQR.G sp|P48668|K2C6C_HUMAN 1 1630.7733 47.89 53143 19865 3 1630.775266 544.5984 "Keratin, type II cytoskeletal 6C OS=Homo sapiens OX=9606 GN=KRT6C PE=1 SV=3" 4.37 3275.2 - 1.18E+07 - - - 1.1939 - 3.681 0.585 - 528 1 2 0 0.0019 15 0 0 0 9.35E+07 1.95E+06 - - - 8.4621 1 221125_WJC_METTL3_EV_vs_WT_F04.19869.19869.3 1.71E-06 Nov-44 R.K[136.11]QVVNIPSFIVR[166.11].L sp|P46781|RS9_HUMAN 1 1416.8572 1.06 53147 19869 3 1416.85773 473.293 40S ribosomal protein S9 OS=Homo sapiens OX=9606 GN=RPS9 PE=1 SV=3 11 3275.5 - 928499 - - - 0.3811 - 2.402 0.473 - 215 1 2 0 0.0005 12 0 0 0 1.07E+08 1.00E+08 - - - 6.2423 0.9997 221125_WJC_METTL3_EV_vs_WT_F04.19872.19872.3 1.22E-06 16/56 R.IPIEDKDLINTANWR.V sp|Q14574|DSC3_HUMAN 1 1796.9421 29.98 53150 19872 3 1796.938428 599.988 Desmocollin-3 OS=Homo sapiens OX=9606 GN=DSC3 PE=1 SV=3 4.56 3275.9 - 663393 - - - -2.0424 - 2.613 0.461 - 228.9 1 2 1 -0.0037 15 0 0 0 2.16E+07 7.22E+05 - - - 6.185 0.9999 221125_WJC_METTL3_EV_vs_WT_F04.19873.19873.3 2.44E-06 17/48 R.RPQTDQAVEFFIR.D "sp|Q8IYB5|SMAP1_HUMAN,tr|A0A087X1X9|A0A087X1X9_HUMAN" 2 1605.8263 1.4 53151 19873 3 1605.828678 536.2827 Stromal membrane-associated protein 1 OS=Homo sapiens OX=9606 GN=SMAP1 PE=1 SV=2 6.07 3276 - 372978 - - - 1.4559 - 2.994 0.421 - 355.6 1 2 0 0.0023 13 0 0 0 5.23E+06 3.72E+06 - - - 6.2063 1 221125_WJC_METTL3_EV_vs_WT_F04.19874.19874.2 1.07E-07 14/32 R.YNQMDSTEDAQEEFGWK.L sp|Q99805|TM9S2_HUMAN 1 2076.8371 1.28 53152 19874 2 2076.843931 1039.4258 Transmembrane 9 superfamily member 2 OS=Homo sapiens OX=9606 GN=TM9SF2 PE=1 SV=1 3.83 3276.1 - 269307 - - - 3.2891 - 3.361 0.731 - 787.5 1 2 0 0.0068 17 0 0 0 2.71E+06 2.11E+06 - - - 7.4184 1 221125_WJC_METTL3_EV_vs_WT_F04.19876.19876.2 2.75E-07 15/30 K.TITLEVEPSDTIENVK[136.11].A "sp|P62979|RS27A_HUMAN,sp|P0CG48|UBC_HUMAN,sp|P0CG47|UBB_HUMAN,sp|P62987|RL40_HUMAN,tr|F5H388|F5H388_HUMAN,tr|F5GYU3|F5GYU3_HUMAN,tr|B4DV12|B4DV12_HUMAN,tr|J3QSA3|J3QSA3_HUMAN,tr|Q5PY61|Q5PY61_HUMAN,tr|F5H2Z3|F5H2Z3_HUMAN,tr|J3QS39|J3QS39_HUMAN,tr|J3QTR3|J3QTR3_HUMAN,tr|Q96C32|Q96C32_HUMAN,tr|M0R1V7|M0R1V7_HUMAN,tr|F5H747|F5H747_HUMAN,tr|F5H747|F5H747_HUMAN,tr|F5GXK7|F5GXK7_HUMAN,tr|F5GXK7|F5GXK7_HUMAN,tr|F5H6Q2|F5H6Q2_HUMAN,tr|F5GZ39|F5GZ39_HUMAN,tr|J3QKN0|J3QKN0_HUMAN,tr|J3QKN0|J3QKN0_HUMAN,tr|J3QKN0|J3QKN0_HUMAN,tr|F5H265|F5H265_HUMAN" 24 1794.9342 0.6 53154 19876 2 1794.932006 898.4744 Ubiquitin-40S ribosomal protein S27a OS=Homo sapiens OX=9606 GN=RPS27A PE=1 SV=2 4 3276.4 - 190442 - - - -1.2363 - 3.055 0.614 - 591 1 2 0 -0.0022 16 0 0 0 8.88E+07 1.47E+08 - - - 6.321 0.9994 221125_WJC_METTL3_EV_vs_WT_F04.19878.19878.3 0.0212 Dec-64 R.GAPPSSNIEDFHGLLPK.G "sp|P43243|MATR3_HUMAN,tr|A8MXP9|A8MXP9_HUMAN,tr|D6R991|D6R991_HUMAN,tr|A0A0R4J2E8|A0A0R4J2E8_HUMAN,tr|H0Y8T4|H0Y8T4_HUMAN,tr|D6REM6|D6REM6_HUMAN" 6 1777.8999 1.57 53155 19878 3 1777.901367 593.6406 Matrin-3 OS=Homo sapiens OX=9606 GN=MATR3 PE=1 SV=2 5.32 3276.7 - 3.56E+06 - - - 0.8257 - 1.883 0.32 - 129.5 1 2 0 0.0015 17 0 0 0 1.73E+09 1.10E+09 - - - 3.7061 1 221125_WJC_METTL3_EV_vs_WT_F04.19882.19882.3 4.89E-08 18/72 R.EDLMGLAIGTHGANIQQAR.K "sp|P51116|FXR2_HUMAN,sp|Q06787|FMR1_HUMAN,tr|A0A087WY29|A0A087WY29_HUMAN,tr|R9WNI0|R9WNI0_HUMAN,tr|A8MQB8|A8MQB8_HUMAN,tr|A0A087WWR6|A0A087WWR6_HUMAN,tr|A0A087WXI3|A0A087WXI3_HUMAN,tr|Q8IXW7|Q8IXW7_HUMAN,tr|G3V0J0|G3V0J0_HUMAN" 9 1994.0004 1.77 53158 19882 3 1994.003587 665.6741 Fragile X mental retardation syndrome-related protein 2 OS=Homo sapiens OX=9606 GN=FXR2 PE=1 SV=2 5.32 3277 - 2.72E+06 - - - 1.6194 - 3.698 0.496 - 431.4 1 2 0 0.0032 19 0 0 0 1.35E+08 7.64E+07 - - - 7.282 1 221125_WJC_METTL3_EV_vs_WT_F04.19883.19883.3 1.90E-11 19/72 R.EDLMGLAIGTHGANIQQAR[166.11].K "sp|P51116|FXR2_HUMAN,sp|Q06787|FMR1_HUMAN,tr|A0A087WY29|A0A087WY29_HUMAN,tr|R9WNI0|R9WNI0_HUMAN,tr|A8MQB8|A8MQB8_HUMAN,tr|A0A087WWR6|A0A087WWR6_HUMAN,tr|A0A087WXI3|A0A087WXI3_HUMAN,tr|Q8IXW7|Q8IXW7_HUMAN,tr|G3V0J0|G3V0J0_HUMAN" 9 2004.0086 1.77 53159 19883 3 2004.010464 669.0102 Fragile X mental retardation syndrome-related protein 2 OS=Homo sapiens OX=9606 GN=FXR2 PE=1 SV=2 5.32 3277.1 - 2.41E+06 - - - 0.9162 - 3.808 0.639 - 522.7 1 2 0 0.0018 19 0 0 0 1.35E+08 7.64E+07 - - - 8.9487 0.9999 221125_WJC_METTL3_EV_vs_WT_F04.19887.19887.3 2.60E-05 14/72 R.SSPLGQNDNSEYVPMLPGK[136.11].F "sp|O14654|IRS4_HUMAN,tr|A0A804CF45|A0A804CF45_HUMAN" 2 2039.9714 1.31 53163 19887 3 2039.975549 680.9977 Insulin receptor substrate 4 OS=Homo sapiens OX=9606 GN=IRS4 PE=1 SV=1 4.37 3277.5 - 747936 - - - 2.0554 - 2.837 0.505 - 166.1 1 2 0 0.0042 19 0 0 0 5.59E+06 4.25E+06 - - - 6.7309 1 221125_WJC_METTL3_EV_vs_WT_F04.19888.19888.3 2.41E-08 15/72 R.SSPLGQNDNSEYVPMLPGK.F "sp|O14654|IRS4_HUMAN,tr|A0A804CF45|A0A804CF45_HUMAN" 2 2031.9572 1.24 53164 19888 3 2031.959219 678.3263 Insulin receptor substrate 4 OS=Homo sapiens OX=9606 GN=IRS4 PE=1 SV=1 4.37 3277.6 - 615933 - - - 1.0153 - 2.854 0.606 - 189.6 1 2 0 0.0021 19 0 0 0 5.26E+06 4.25E+06 - - - 7.8722 0.9999 221125_WJC_METTL3_EV_vs_WT_F04.19889.19889.3 0.000558 Dec-64 R.YNQMDSTEDAQEEFGWK.L sp|Q99805|TM9S2_HUMAN 1 2076.8371 1.25 53165 19889 3 2076.841169 693.2863 Transmembrane 9 superfamily member 2 OS=Homo sapiens OX=9606 GN=TM9SF2 PE=1 SV=1 3.83 3277.7 - 591980 - - - 1.9592 - 2.163 0.502 - 201.6 1 2 0 0.0041 17 0 0 0 2.84E+06 2.27E+06 - - - 6.0847 1 221125_WJC_METTL3_EV_vs_WT_F04.19891.19891.2 1.27E-07 16/28 R.DISSSLNSLADSNAR[166.11].E sp|O94776|MTA2_HUMAN 1 1558.7462 1.25 53167 19891 2 1558.747346 780.3804 Metastasis-associated protein MTA2 OS=Homo sapiens OX=9606 GN=MTA2 PE=1 SV=1 4.21 3278 - 524521 - - - 0.7038 - 3.085 0.585 - 773.4 1 2 0 0.0011 15 0 0 0 4.50E+06 3.60E+06 - - - 6.1311 1 221125_WJC_METTL3_EV_vs_WT_F04.19893.19893.2 9.10E-08 16/30 K.TITLEVEPSDTIENVK.A "sp|P62979|RS27A_HUMAN,sp|P0CG48|UBC_HUMAN,sp|P0CG47|UBB_HUMAN,sp|P62987|RL40_HUMAN,tr|F5H388|F5H388_HUMAN,tr|F5GYU3|F5GYU3_HUMAN,tr|B4DV12|B4DV12_HUMAN,tr|J3QSA3|J3QSA3_HUMAN,tr|Q5PY61|Q5PY61_HUMAN,tr|F5H2Z3|F5H2Z3_HUMAN,tr|J3QS39|J3QS39_HUMAN,tr|J3QTR3|J3QTR3_HUMAN,tr|Q96C32|Q96C32_HUMAN,tr|M0R1V7|M0R1V7_HUMAN,tr|F5H747|F5H747_HUMAN,tr|F5H747|F5H747_HUMAN,tr|F5GXK7|F5GXK7_HUMAN,tr|F5GXK7|F5GXK7_HUMAN,tr|F5H6Q2|F5H6Q2_HUMAN,tr|F5GZ39|F5GZ39_HUMAN,tr|J3QKN0|J3QKN0_HUMAN,tr|J3QKN0|J3QKN0_HUMAN,tr|J3QKN0|J3QKN0_HUMAN,tr|F5H265|F5H265_HUMAN" 24 1786.92 0.62 53169 19893 2 1786.924478 894.4673 Ubiquitin-40S ribosomal protein S27a OS=Homo sapiens OX=9606 GN=RPS27A PE=1 SV=2 4 3278.3 - 405486 - - - 2.492 - 3.411 0.62 - 640.9 1 2 0 0.0045 16 0 0 0 8.88E+07 1.43E+08 - - - 6.6356 0.9998 221125_WJC_METTL3_EV_vs_WT_F04.19896.19896.2 1.47E-06 14/28 R.TQETPSAQMEGFLNR[166.11].K "sp|Q01082|SPTB2_HUMAN,tr|A0A087WUZ3|A0A087WUZ3_HUMAN" 2 1717.7969 1.52 53172 19896 2 1717.793655 859.9057 "Spectrin beta chain, non-erythrocytic 1 OS=Homo sapiens OX=9606 GN=SPTBN1 PE=1 SV=2" 4.53 3278.6 - 314784 - - - -1.8914 - 2.95 0.516 - 545.9 1 2 0 -0.0032 15 0 0 0 4.14E+06 2.72E+06 - - - 5.5108 0.9998 221125_WJC_METTL3_EV_vs_WT_F04.19901.19901.2 2.00E-06 Nov-34 K.VDFSPQPPYNYAVTASSR.L "sp|Q8TED0|UTP15_HUMAN,tr|H0Y8P4|H0Y8P4_HUMAN,tr|D6RF65|D6RF65_HUMAN" 3 1997.9483 2.08 53176 19901 2 1997.945929 999.9814 U3 small nucleolar RNA-associated protein 15 homolog OS=Homo sapiens OX=9606 GN=UTP15 PE=1 SV=3 5.81 3279.3 - 222214 - - - -1.1897 - 2.129 0.52 - 181.8 1 2 0 -0.0024 18 0 0 0 1.33E+06 6.39E+05 - - - 4.7388 0.9999 221125_WJC_METTL3_EV_vs_WT_F04.19903.19903.3 0.000136 16/56 K.QTELFAHFIQPAAQK.T sp|O60264|SMCA5_HUMAN 1 1727.8995 0.85 53177 19903 3 1727.901179 576.9738 SWI\SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A member 5 OS=Homo sapiens OX=9606 GN=SMARCA5 PE=1 SV=1 6.75 3279.5 - 1.44E+06 - - - 0.9688 - 2.38 0.416 - 316.1 1 2 0 0.0017 15 0 0 0 1.22E+07 1.44E+07 - - - 5.4401 0.9983 221125_WJC_METTL3_EV_vs_WT_F04.19904.19904.3 1.66E-06 15/60 K.TITLEVEPSDTIENVK[136.11].A "sp|P62979|RS27A_HUMAN,sp|P0CG48|UBC_HUMAN,sp|P0CG47|UBB_HUMAN,sp|P62987|RL40_HUMAN,tr|F5H388|F5H388_HUMAN,tr|F5GYU3|F5GYU3_HUMAN,tr|B4DV12|B4DV12_HUMAN,tr|J3QSA3|J3QSA3_HUMAN,tr|Q5PY61|Q5PY61_HUMAN,tr|F5H2Z3|F5H2Z3_HUMAN,tr|J3QS39|J3QS39_HUMAN,tr|J3QTR3|J3QTR3_HUMAN,tr|Q96C32|Q96C32_HUMAN,tr|M0R1V7|M0R1V7_HUMAN,tr|F5H747|F5H747_HUMAN,tr|F5H747|F5H747_HUMAN,tr|F5GXK7|F5GXK7_HUMAN,tr|F5GXK7|F5GXK7_HUMAN,tr|F5H6Q2|F5H6Q2_HUMAN,tr|F5GZ39|F5GZ39_HUMAN,tr|J3QKN0|J3QKN0_HUMAN,tr|J3QKN0|J3QKN0_HUMAN,tr|J3QKN0|J3QKN0_HUMAN,tr|F5H265|F5H265_HUMAN" 24 1794.9342 1.03 53178 19904 3 1795.93833 599.3187 Ubiquitin-40S ribosomal protein S27a OS=Homo sapiens OX=9606 GN=RPS27A PE=1 SV=2 4 3279.6 - 1.51E+06 - - - 559.4105 - 2.597 0.441 - 222.2 1 2 0 1.0041 16 0 0 0 3.93E+07 3.80E+07 - - - 5.6273 0.9998 221125_WJC_METTL3_EV_vs_WT_F04.19905.19905.3 0.00278 Nov-48 K.K[136.11]YDAFLASESLIK[136.11].Q sp|P62906|RL10A_HUMAN 1 1499.8206 1.2 53179 19905 3 1499.822282 500.9475 60S ribosomal protein L10a OS=Homo sapiens OX=9606 GN=RPL10A PE=1 SV=2 6.07 3279.7 - 888129 - - - 1.0908 - 2.025 0.392 - 126.6 1 2 0 0.0016 13 0 0 0 1.24E+07 1.03E+07 - - - 4.823 1 221125_WJC_METTL3_EV_vs_WT_F04.19906.19906.3 0.00172 14/56 K.QHNIFLDQMTIDEDK.L "sp|P52732|KIF11_HUMAN,tr|A0A7I2V3A9|A0A7I2V3A9_HUMAN" 2 1845.8567 5.22 53180 19906 3 1845.856328 616.2928 Kinesin-like protein KIF11 OS=Homo sapiens OX=9606 GN=KIF11 PE=1 SV=2 4.22 3279.8 - 859689 - - - -0.2091 - 2.849 0.511 - 252.1 1 2 0 -0.0004 15 0 0 0 2.16E+07 4.14E+06 - - - 6.969 0.9997 221125_WJC_METTL3_EV_vs_WT_F04.19908.19908.3 2.48E-06 Nov-56 K.TQLLQDVQDENKLFK.S "sp|Q86UP2|KTN1_HUMAN,tr|G3V4Y7|G3V4Y7_HUMAN,tr|H0YJV5|H0YJV5_HUMAN" 3 1817.9523 1.61 53182 19908 3 1817.954321 606.9914 Kinectin OS=Homo sapiens OX=9606 GN=KTN1 PE=1 SV=1 4.56 3280 - 756374 - - - 1.0957 - 2.541 0.44 - 128.9 1 2 1 0.002 15 0 0 0 5.89E+06 3.65E+06 - - - 5.8784 0.9937 221125_WJC_METTL3_EV_vs_WT_F04.19909.19909.3 0.000249 Dec-48 K.KYDAFLASESLIK.Q sp|P62906|RL10A_HUMAN 1 1483.7922 1.2 53183 19909 3 1483.793022 495.6047 60S ribosomal protein L10a OS=Homo sapiens OX=9606 GN=RPL10A PE=1 SV=2 6.07 3280.1 - 739655 - - - 0.523 - 2.224 0.124 - 132.8 1 2 0 0.0008 13 0 0 0 1.24E+07 1.03E+07 - - - 2.0894 1 221125_WJC_METTL3_EV_vs_WT_F04.19910.19910.3 4.67E-10 20/72 R.NLAMEATYINHNFSQQC[160.03]LR.M sp|O15371|EIF3D_HUMAN 1 2309.0681 1.03 53184 19910 3 2309.069879 770.6967 Eukaryotic translation initiation factor 3 subunit D OS=Homo sapiens OX=9606 GN=EIF3D PE=1 SV=1 6.74 3280.3 - 722528 - - - 0.7613 - 4.283 0.654 - 379.3 1 2 0 0.0018 19 0 0 0 3.39E+07 3.31E+07 - - - 9.4048 1 221125_WJC_METTL3_EV_vs_WT_F04.19912.19912.2 1.19E-08 26-Dec K.EAC[160.03]WTISNITAGNR.A "sp|O60684|IMA7_HUMAN,sp|P52294|IMA5_HUMAN,tr|Q5TFJ7|Q5TFJ7_HUMAN" 3 1591.7413 0.66 53186 19912 2 1591.742737 796.8779 Importin subunit alpha-7 OS=Homo sapiens OX=9606 GN=KPNA6 PE=1 SV=1 6.09 3280.5 - 523065 - - - 0.9091 - 2.392 0.653 - 530.7 1 2 0 0.0014 14 0 0 0 3.65E+06 5.54E+06 - - - 6.0522 0.9981 221125_WJC_METTL3_EV_vs_WT_F04.19916.19916.2 0.00495 Jul-36 R.SSPLGQNDNSEYVPMLPGK[136.11].F "sp|O14654|IRS4_HUMAN,tr|A0A804CF45|A0A804CF45_HUMAN" 2 2039.9714 1.36 53190 19916 2 2039.975923 1020.993 Insulin receptor substrate 4 OS=Homo sapiens OX=9606 GN=IRS4 PE=1 SV=1 4.37 3281 - 284885 - - - 2.2388 - 1.416 0.378 - 79.2 1 2 0 0.0046 19 0 0 0 3.27E+06 2.41E+06 - - - 2.6866 0.9999 221125_WJC_METTL3_EV_vs_WT_F04.19921.19921.3 0.00632 26/76 R.VGQQAIVLC[160.03]ISPSKPNPVFK.V "sp|Q16656|NRF1_HUMAN,tr|C9JP85|C9JP85_HUMAN" 2 2181.198 2.49 53193 19921 3 2181.198887 728.0733 Nuclear respiratory factor 1 OS=Homo sapiens OX=9606 GN=NRF1 PE=1 SV=1 9.31 3281.7 - 1.75E+06 - - - 0.4085 - 4.359 0.327 - 640.7 1 2 0 0.0009 20 0 0 0 9.23E+07 3.71E+07 - - - 5.7572 0.9999 221125_WJC_METTL3_EV_vs_WT_F04.19922.19922.3 0.000211 16/60 K.TITLEVEPSDTIENVK.A "sp|P62979|RS27A_HUMAN,sp|P0CG48|UBC_HUMAN,sp|P0CG47|UBB_HUMAN,sp|P62987|RL40_HUMAN,tr|F5H388|F5H388_HUMAN,tr|F5GYU3|F5GYU3_HUMAN,tr|B4DV12|B4DV12_HUMAN,tr|J3QSA3|J3QSA3_HUMAN,tr|Q5PY61|Q5PY61_HUMAN,tr|F5H2Z3|F5H2Z3_HUMAN,tr|J3QS39|J3QS39_HUMAN,tr|J3QTR3|J3QTR3_HUMAN,tr|Q96C32|Q96C32_HUMAN,tr|M0R1V7|M0R1V7_HUMAN,tr|F5H747|F5H747_HUMAN,tr|F5H747|F5H747_HUMAN,tr|F5GXK7|F5GXK7_HUMAN,tr|F5GXK7|F5GXK7_HUMAN,tr|F5H6Q2|F5H6Q2_HUMAN,tr|F5GZ39|F5GZ39_HUMAN,tr|J3QKN0|J3QKN0_HUMAN,tr|J3QKN0|J3QKN0_HUMAN,tr|J3QKN0|J3QKN0_HUMAN,tr|F5H265|F5H265_HUMAN" 24 1786.92 0.86 53194 19922 3 1786.921445 596.6473 Ubiquitin-40S ribosomal protein S27a OS=Homo sapiens OX=9606 GN=RPS27A PE=1 SV=2 4 3281.7 - 2.44E+06 - - - 0.7947 - 2.611 0.398 - 262.5 1 2 0 0.0014 16 0 0 0 2.90E+07 3.36E+07 - - - 5.4395 0.9931 221125_WJC_METTL3_EV_vs_WT_F04.19924.19924.3 2.59E-05 20/44 L.NNQFASFIDKVR.F "sp|Q8N1N4|K2C78_HUMAN,sp|P04264|K2C1_HUMAN" 2 1437.7365 48.21 53196 19924 3 1437.738534 480.2528 "Keratin, type II cytoskeletal 78 OS=Homo sapiens OX=9606 GN=KRT78 PE=1 SV=2" 8.75 3282 - 910436 - - - 1.4412 - 3.305 0.57 - 686.4 1 1 1 0.0021 12 0 0 0 1.43E+07 2.97E+05 - - - 8.2079 1 221125_WJC_METTL3_EV_vs_WT_F04.19927.19927.3 5.30E-08 20/48 R.RGQNFQVLMIMNK.G "sp|Q08188|TGM3_HUMAN,tr|A0A494C0J7|A0A494C0J7_HUMAN" 2 1577.817 999 53199 19927 3 1577.820096 526.9463 Protein-glutamine gamma-glutamyltransferase E OS=Homo sapiens OX=9606 GN=TGM3 PE=1 SV=4 11 3282.3 - 766241 - - - 1.9381 - 3.398 0.523 - 573.8 1 2 0 0.0031 13 0 0 0 1.96E+07 0.00E+00 - - - 7.6865 0.9993 221125_WJC_METTL3_EV_vs_WT_F04.19929.19929.3 2.39E-07 22/52 K.TQSKPFSIQELELR.S "sp|Q9Y618|NCOR2_HUMAN,tr|C9J7T7|C9J7T7_HUMAN,tr|C9JE98|C9JE98_HUMAN,tr|C9J0Q5|C9J0Q5_HUMAN,tr|A0A384DVL6|A0A384DVL6_HUMAN" 5 1674.8941 2.12 53201 19929 3 1674.90431 559.3053 Nuclear receptor corepressor 2 OS=Homo sapiens OX=9606 GN=NCOR2 PE=1 SV=3 5.81 3282.6 - 585803 - - - 6.1049 - 3.209 0.481 - 687.5 1 2 0 0.0102 14 0 0 0 2.06E+07 9.71E+06 - - - 6.9984 0.9999 221125_WJC_METTL3_EV_vs_WT_F04.19938.19938.3 6.73E-05 15/68 K.HLVGVDSLIGPETQIGEK[136.11].S "sp|Q9NR50|EI2BG_HUMAN,tr|H0Y580|H0Y580_HUMAN" 2 1899.0193 1.09 53208 19938 3 1899.023719 634.0137 Translation initiation factor eIF-2B subunit gamma OS=Homo sapiens OX=9606 GN=EIF2B3 PE=1 SV=1 4.65 3283.6 - 722958 - - - 2.3312 - 3.2 0.473 - 312.2 1 2 0 0.0044 18 0 0 0 1.20E+07 1.10E+07 - - - 6.7086 1 221125_WJC_METTL3_EV_vs_WT_F04.19941.19941.3 1.05E-05 15/64 R.AGAFDAVPC[160.03]YHWSVGGK[136.11].G "sp|Q6UB35|C1TM_HUMAN,tr|Q4VXV2|Q4VXV2_HUMAN,tr|A0A087WVM4|A0A087WVM4_HUMAN,tr|B7ZM99|B7ZM99_HUMAN" 4 1828.8446 0.68 53211 19941 3 1828.843229 610.6222 "Monofunctional C1-tetrahydrofolate synthase, mitochondrial OS=Homo sapiens OX=9606 GN=MTHFD1L PE=1 SV=1" 6.78 3284 - 456492 - - - -0.7715 - 2.39 0.501 - 289.3 1 2 0 -0.0014 17 0 0 0 3.36E+06 4.96E+06 - - - 6.3264 0.9235 221125_WJC_METTL3_EV_vs_WT_F04.19942.19942.2 4.2 24-Jun R.KLDFSRPEPC[160.03]FEK.E sp|Q6ZS62|COLC1_HUMAN 1 1651.8028 999 53212 19942 2 1651.804808 826.9087 Colorectal cancer-associated protein 1 OS=Homo sapiens OX=9606 GN=COLCA1 PE=2 SV=1 6.17 3284.2 - 387063 - - - 1.1987 - 1.133 0.021 - 76.2 1 2 0 0.002 13 0 0 0 1.38E+08 0.00E+00 - - - -0.484 1 221125_WJC_METTL3_EV_vs_WT_F04.19947.19947.3 2.51E-11 20/100 R.GAYGGGYGGYDDYNGYNDGYGFGSDR.F "sp|P31943|HNRH1_HUMAN,tr|H0YBD7|H0YBD7_HUMAN,tr|H0YB39|H0YB39_HUMAN,tr|E9PCY7|E9PCY7_HUMAN,tr|G8JLB6|G8JLB6_HUMAN" 5 2716.0375 1.17 53215 19947 3 2716.034134 906.3531 Heterogeneous nuclear ribonucleoprotein H OS=Homo sapiens OX=9606 GN=HNRNPH1 PE=1 SV=4 3.77 3284.8 - 915760 - - - -1.2275 - 3.054 0.785 - 315.1 1 2 0 -0.0033 26 0 0 0 2.18E+07 1.87E+07 - - - 9.8596 1 221125_WJC_METTL3_EV_vs_WT_F04.19948.19948.3 1.33E-06 14/68 K.HLVGVDSLIGPETQIGEK.S "sp|Q9NR50|EI2BG_HUMAN,tr|H0Y580|H0Y580_HUMAN" 2 1891.0051 0.92 53216 19948 3 1891.006546 631.3423 Translation initiation factor eIF-2B subunit gamma OS=Homo sapiens OX=9606 GN=EIF2B3 PE=1 SV=1 4.65 3284.9 - 769061 - - - 0.7689 - 3.146 0.411 - 167.3 1 2 0 0.0015 18 0 0 0 1.20E+07 1.30E+07 - - - 5.9758 0.9996 221125_WJC_METTL3_EV_vs_WT_F04.19950.19950.3 1.57E-07 16/64 K.TR[166.11]NPTFNEMLVYSGYSK[136.11].E sp|O00443|P3C2A_HUMAN 1 2023.9792 0.39 53218 19950 3 2023.973176 675.667 Phosphatidylinositol 4-phosphate 3-kinase C2 domain-containing subunit alpha OS=Homo sapiens OX=9606 GN=PIK3C2A PE=1 SV=2 8.17 3285.2 - 452941 - - - -2.9921 - 3.253 0.476 - 417.6 1 2 1 -0.0061 17 0 0 0 2.82E+06 7.21E+06 - - - 6.8252 0.9538 221125_WJC_METTL3_EV_vs_WT_F04.19952.19952.3 4.13E-09 15/64 V.LEDTENWLYEDGEDQPK[136.11].Q "sp|O95757|HS74L_HUMAN,sp|P34932|HSP74_HUMAN,tr|E9PDE8|E9PDE8_HUMAN,tr|A0A087WYC1|A0A087WYC1_HUMAN" 4 2087.9051 0.06 53220 19952 3 2088.910186 696.9756 Heat shock 70 kDa protein 4L OS=Homo sapiens OX=9606 GN=HSPA4L PE=1 SV=3 3.66 3285.5 - 269011 - - - 481.3801 - 2.647 0.604 - 309.5 1 1 0 1.0051 17 0 0 0 5.45E+06 9.54E+07 - - - 7.4548 0.9998 221125_WJC_METTL3_EV_vs_WT_F04.19959.19959.3 0.000452 13/60 K.FEQLSESAKEELINFK.R sp|Q9Y5X3|SNX5_HUMAN 1 1910.9626 0.95 53225 19959 3 1910.960361 637.9948 Sorting nexin-5 OS=Homo sapiens OX=9606 GN=SNX5 PE=1 SV=1 4.49 3286.2 - 665691 - - - -1.1502 - 2.706 0.472 - 164.4 1 2 1 -0.0022 16 0 0 0 2.73E+06 2.89E+06 - - - 6.356 0.9999 221125_WJC_METTL3_EV_vs_WT_F04.19966.19966.3 2.73E-08 26/72 R.AAISSGIEDPVPTLHLTER[166.11].D "sp|O75175|CNOT3_HUMAN,tr|A0A2R8Y691|A0A2R8Y691_HUMAN,tr|B7Z6J7|B7Z6J7_HUMAN,tr|A0A2H2FJL5|A0A2H2FJL5_HUMAN,tr|H7C3F5|H7C3F5_HUMAN,tr|A0A2R8Y4W0|A0A2R8Y4W0_HUMAN,tr|H0Y5X7|H0Y5X7_HUMAN" 7 2015.0563 5.58 53230 19966 3 2015.048331 672.6927 CCR4-NOT transcription complex subunit 3 OS=Homo sapiens OX=9606 GN=CNOT3 PE=1 SV=1 4.65 3287.1 - 1.90E+06 - - - -3.9498 - 4.032 0.571 - 597.5 1 2 0 -0.008 19 0 0 0 2.27E+08 4.06E+07 - - - 8.3293 1 221125_WJC_METTL3_EV_vs_WT_F04.19967.19967.3 2.56E-09 15/56 R.KFGYVDFESAEDLEK.A "sp|P19338|NUCL_HUMAN,tr|A0A7I2V506|A0A7I2V506_HUMAN,tr|A0A7I2V699|A0A7I2V699_HUMAN,tr|A0A7I2V2U7|A0A7I2V2U7_HUMAN,tr|A0A7I2V3F3|A0A7I2V3F3_HUMAN,tr|A0A7I2V428|A0A7I2V428_HUMAN,tr|A0A7I2V349|A0A7I2V349_HUMAN,tr|H7BY16|H7BY16_HUMAN,tr|A0A7I2V5M5|A0A7I2V5M5_HUMAN,tr|A0A7I2V2S8|A0A7I2V2S8_HUMAN,tr|C9JLB1|C9JLB1_HUMAN" 11 1775.8254 1.18 53231 19967 3 1775.821777 592.9491 Nucleolin OS=Homo sapiens OX=9606 GN=NCL PE=1 SV=3 4.18 3287.1 - 1.80E+06 - - - -2.0385 - 3.448 0.571 - 428.1 1 2 0 -0.0036 15 0 0 0 2.46E+08 2.09E+08 - - - 8.1349 1 221125_WJC_METTL3_EV_vs_WT_F04.19977.19977.3 2.55E-08 20/56 R.K[136.11]FGYVDFESAEDLEK[136.11].A "sp|P19338|NUCL_HUMAN,tr|A0A7I2V506|A0A7I2V506_HUMAN,tr|A0A7I2V699|A0A7I2V699_HUMAN,tr|A0A7I2V2U7|A0A7I2V2U7_HUMAN,tr|A0A7I2V3F3|A0A7I2V3F3_HUMAN,tr|A0A7I2V428|A0A7I2V428_HUMAN,tr|A0A7I2V349|A0A7I2V349_HUMAN,tr|H7BY16|H7BY16_HUMAN,tr|A0A7I2V5M5|A0A7I2V5M5_HUMAN,tr|A0A7I2V2S8|A0A7I2V2S8_HUMAN,tr|C9JLB1|C9JLB1_HUMAN" 11 1791.8538 1.18 53238 19977 3 1791.848766 598.2919 Nucleolin OS=Homo sapiens OX=9606 GN=NCL PE=1 SV=3 4.18 3288.2 - 3.80E+06 - - - -2.8077 - 3.76 0.644 - 698.2 1 2 0 -0.005 15 0 0 0 2.46E+08 2.09E+08 - - - 9.1745 1 221125_WJC_METTL3_EV_vs_WT_F04.19978.19978.2 8.31E-06 22-Sep K.HTDESLGDC[160.03]SFL.N "sp|Q86U44|MTA70_HUMAN,tr|H0YFV6|H0YFV6_HUMAN" 2 1379.5663 - 53239 19978 2 1379.560553 690.7904 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 4.02 3288.4 - 1.62E+06 - - - -4.1984 - 2.07 0.646 - 136.3 1 1 0 -0.0058 12 0 0 0 - - - - - 5.7248 0.9999 221125_WJC_METTL3_EV_vs_WT_F04.19985.19985.2 9.22E-05 13/20 K.NALESYAFNMK[136.11].S "sp|P0DMV8|HS71A_HUMAN,sp|P34931|HS71L_HUMAN,sp|P0DMV9|HS71B_HUMAN,tr|Q53FA3|Q53FA3_HUMAN,tr|V9GZ37|V9GZ37_HUMAN,tr|A0A0G2JIW1|A0A0G2JIW1_HUMAN" 6 1294.6107 0.4 53243 19985 2 1294.610282 648.3126 Heat shock 70 kDa protein 1A OS=Homo sapiens OX=9606 GN=HSPA1A PE=1 SV=1 6 3289.3 - 2.81E+06 - - - -0.3406 - 2.592 0.546 - 701 1 2 0 -0.0004 11 0 0 0 1.67E+07 4.23E+07 - - - 5.6502 0.9503 221125_WJC_METTL3_EV_vs_WT_F04.19990.19990.3 1.44E-05 16/72 R.QVDDLEVWSHTNDTIGSVR[166.11].R sp|Q93008|USP9X_HUMAN 1 2180.0373 0.46 53246 19990 3 2181.053294 727.6864 Probable ubiquitin carboxyl-terminal hydrolase FAF-X OS=Homo sapiens OX=9606 GN=USP9X PE=1 SV=4 4.22 3289.9 - 4.53E+06 - - - 466.0237 - 2.37 0.472 - 116 1 2 0 1.0159 19 0 0 0 4.19E+07 9.10E+07 - - - 5.6409 1 221125_WJC_METTL3_EV_vs_WT_F04.20004.20004.2 3.30E-10 20/32 V.LEDTENWLYEDGEDQPK[136.11].Q "sp|O95757|HS74L_HUMAN,sp|P34932|HSP74_HUMAN,tr|E9PDE8|E9PDE8_HUMAN,tr|A0A087WYC1|A0A087WYC1_HUMAN" 4 2087.9051 0.001 53251 20004 2 2087.899137 1044.9598 Heat shock 70 kDa protein 4L OS=Homo sapiens OX=9606 GN=HSPA4L PE=1 SV=3 3.66 3291.8 - 2.51E+06 - - - -2.8608 - 3.842 0.734 - 1278.8 1 1 0 -0.006 17 0 0 0 0.00E+00 8.48E+07 - - - 7.7696 0.9988 221125_WJC_METTL3_EV_vs_WT_F04.20005.20005.2 0.00432 14-Nov R.VDEIIWVK[136.11].T sp|Q86U44|MTA70_HUMAN 1 1008.5735 0.01 53252 20005 2 1008.569796 505.294 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 4.37 3291.9 - 3.49E+06 - - - -3.7052 - 2.306 0.379 - 407.8 1 2 0 -0.0037 8 0 0 0 2.69E+06 5.32E+08 - - - 4.359 1 221125_WJC_METTL3_EV_vs_WT_F04.20022.20022.3 1.25E-08 17/60 F.ASFNDTFVHVTDLSGK.E "sp|P62263|RS14_HUMAN,tr|A0A2R8Y811|A0A2R8Y811_HUMAN,tr|E5RH77|E5RH77_HUMAN" 3 1736.837 1.35 53257 20022 3 1736.83288 579.9529 40S ribosomal protein S14 OS=Homo sapiens OX=9606 GN=RPS14 PE=1 SV=3 5.21 3294.3 - 4.70E+06 - - - -2.3514 - 3.358 0.619 - 214.1 1 1 0 -0.0041 16 0 0 0 3.47E+08 2.58E+08 - - - 8.5483 0.9993 221125_WJC_METTL3_EV_vs_WT_F04.20023.20023.2 4.50E-07 15/22 K.LNDLEEALQQAK.E sp|P35908|K22E_HUMAN 1 1370.7042 999 53258 20023 2 1370.699174 686.3594 "Keratin, type II cytoskeletal 2 epidermal OS=Homo sapiens OX=9606 GN=KRT2 PE=1 SV=2" 4.14 3294.4 - 2.79E+06 - - - -3.6368 - 3.005 0.433 - 904.1 1 2 0 -0.005 12 0 0 0 1.21E+08 0.00E+00 - - - 5.1326 1 221125_WJC_METTL3_EV_vs_WT_F04.20032.20032.2 4.71E-11 18/32 R.SLGYAYVNFQQPADAER.A "sp|Q13310|PABP4_HUMAN,sp|P11940|PABP1_HUMAN,tr|A0A7I2V649|A0A7I2V649_HUMAN,tr|B1ANR0|B1ANR0_HUMAN,tr|A0A7I2V4L7|A0A7I2V4L7_HUMAN,tr|E5RHG7|E5RHG7_HUMAN,tr|B1ANR1|B1ANR1_HUMAN,tr|H0YAR2|H0YAR2_HUMAN,tr|E7ERJ7|E7ERJ7_HUMAN,tr|E5RJB9|E5RJB9_HUMAN,tr|A0A7I2YQ88|A0A7I2YQ88_HUMAN,tr|E5RH24|E5RH24_HUMAN,tr|H0YBN4|H0YBN4_HUMAN,tr|E5RGH3|E5RGH3_HUMAN,tr|A0A087WTT1|A0A087WTT1_HUMAN,tr|A0A7I2YQ90|A0A7I2YQ90_HUMAN,tr|E7EQV3|E7EQV3_HUMAN" 17 1927.9064 2.59 53259 20032 2 1927.905485 964.9605 Polyadenylate-binding protein 4 OS=Homo sapiens OX=9606 GN=PABPC4 PE=1 SV=1 4.37 3295.8 - 3.14E+06 - - - -0.4959 - 3.446 0.702 - 1092.2 1 2 0 -0.001 17 0 0 0 1.03E+08 3.99E+07 - - - 7.2674 1 221125_WJC_METTL3_EV_vs_WT_F04.20033.20033.2 5.29E-15 22/32 R.TDASSASSFLDSDELER[166.11].T "sp|Q14498|RBM39_HUMAN,tr|A0A0U1RQW2|A0A0U1RQW2_HUMAN,tr|H0Y4X3|H0Y4X3_HUMAN,tr|A0A0U1RQH7|A0A0U1RQH7_HUMAN,tr|G3XAC6|G3XAC6_HUMAN" 5 1838.8046 1.72 53260 20033 2 1838.804356 920.4096 RNA-binding protein 39 OS=Homo sapiens OX=9606 GN=RBM39 PE=1 SV=2 3.77 3295.9 - 3.10E+06 - - - -0.106 - 3.427 0.62 - 1007.4 1 2 0 -0.0002 17 0 0 0 1.27E+08 7.39E+07 - - - 6.6484 1 221125_WJC_METTL3_EV_vs_WT_F04.20034.20034.3 4.80E-14 22/64 K.KFYPLEIDYGQDEEAVK.K sp|P09874|PARP1_HUMAN 1 2042.9837 1.21 53261 20034 3 2042.986086 682.0018 Poly [ADP-ribose] polymerase 1 OS=Homo sapiens OX=9606 GN=PARP1 PE=1 SV=4 4.18 3296.1 - 2.73E+06 - - - 1.1738 - 3.798 0.657 - 846.4 1 2 0 0.0024 17 0 0 0 1.04E+08 8.55E+07 - - - 9.2355 1 221125_WJC_METTL3_EV_vs_WT_F04.20039.20039.3 2.16E-09 21/60 R.LQQELDDLTVDLDHQR.Q sp|P35580|MYH10_HUMAN 1 1936.949 0.97 53263 20039 3 1936.948539 646.657 Myosin-10 OS=Homo sapiens OX=9606 GN=MYH10 PE=1 SV=3 4.03 3296.7 - 5.51E+06 - - - -0.2556 - 3.662 0.557 - 692.6 1 2 0 -0.0005 16 0 0 0 1.61E+08 1.67E+08 - - - 8.0804 1 221125_WJC_METTL3_EV_vs_WT_F04.20040.20040.2 2.11E-12 21/32 R.TDASSASSFLDSDELER.T "sp|Q14498|RBM39_HUMAN,tr|A0A0U1RQW2|A0A0U1RQW2_HUMAN,tr|H0Y4X3|H0Y4X3_HUMAN,tr|A0A0U1RQH7|A0A0U1RQH7_HUMAN,tr|G3XAC6|G3XAC6_HUMAN" 5 1828.7963 1.72 53264 20040 2 1828.790076 915.4054 RNA-binding protein 39 OS=Homo sapiens OX=9606 GN=RBM39 PE=1 SV=2 3.77 3296.8 - 4.87E+06 - - - -3.3929 - 3.841 0.669 - 1846.4 1 2 0 -0.0062 17 0 0 0 1.27E+08 7.39E+07 - - - 7.2888 1 221125_WJC_METTL3_EV_vs_WT_F04.20041.20041.3 2.96E-10 25/60 R.LQQELDDLTVDLDHQR[166.11].Q sp|P35580|MYH10_HUMAN 1 1946.9573 0.96 53265 20041 3 1946.955609 649.993 Myosin-10 OS=Homo sapiens OX=9606 GN=MYH10 PE=1 SV=3 4.03 3296.9 - 3.94E+06 - - - -0.8706 - 3.918 0.578 - 1119.2 1 2 0 -0.0017 16 0 0 0 1.61E+08 1.67E+08 - - - 8.4876 1 221125_WJC_METTL3_EV_vs_WT_F04.20052.20052.3 2.45E-06 24/52 K.R[166.11]PSENLGQVLFGER[166.11].L sp|Q99805|TM9S2_HUMAN 1 1620.8487 1.27 53272 20052 3 1620.84556 541.2902 Transmembrane 9 superfamily member 2 OS=Homo sapiens OX=9606 GN=TM9SF2 PE=1 SV=1 6.14 3298.3 - 2.01E+06 - - - -1.9336 - 4.199 0.595 - 1265.9 1 2 0 -0.0031 14 0 0 0 8.10E+07 6.37E+07 - - - 8.9859 0.9991 221125_WJC_METTL3_EV_vs_WT_F04.20053.20053.3 9.81E-07 16/64 R.TENPVIMGLSSQNGQLR.G "sp|P26196|DDX6_HUMAN,tr|Q8IV96|Q8IV96_HUMAN" 2 1842.9258 1.21 53273 20053 3 1842.932138 615.3159 Probable ATP-dependent RNA helicase DDX6 OS=Homo sapiens OX=9606 GN=DDX6 PE=1 SV=2 5.66 3298.4 - 1.97E+06 - - - 3.4413 - 3.116 0.296 - 326.8 1 2 0 0.0063 17 0 0 0 3.85E+07 3.19E+07 - - - 4.7096 1 221125_WJC_METTL3_EV_vs_WT_F04.20056.20056.3 3.59E-11 25/52 K.RPSENLGQVLFGER.L sp|Q99805|TM9S2_HUMAN 1 1600.8322 1.27 53274 20056 3 1600.82801 534.618 Transmembrane 9 superfamily member 2 OS=Homo sapiens OX=9606 GN=TM9SF2 PE=1 SV=1 6.14 3298.8 - 4.20E+06 - - - -2.5887 - 4.241 0.466 - 1390.8 1 2 0 -0.0041 14 0 0 0 8.10E+07 6.39E+07 - - - 7.5739 0.9999 221125_WJC_METTL3_EV_vs_WT_F04.20057.20057.3 2.06E-08 14/64 K.K[136.11]FYPLEIDYGQDEEAVK[136.11].K sp|P09874|PARP1_HUMAN 1 2059.0121 1.21 53275 20057 3 2059.004819 687.3446 Poly [ADP-ribose] polymerase 1 OS=Homo sapiens OX=9606 GN=PARP1 PE=1 SV=4 4.18 3298.9 - 4.03E+06 - - - -3.5303 - 3.145 0.615 - 329.1 1 2 0 -0.0073 17 0 0 0 1.04E+08 8.53E+07 - - - 8.2893 1 221125_WJC_METTL3_EV_vs_WT_F04.20058.20058.3 0.000267 20/60 R.EVIDLLKPDQVEGIQK.S sp|Q86UP2|KTN1_HUMAN 1 1823.004 1.62 53276 20058 3 1823.001434 608.6753 Kinectin OS=Homo sapiens OX=9606 GN=KTN1 PE=1 SV=1 4.32 3299 - 3.87E+06 - - - -1.424 - 3.514 0.45 - 502.5 1 2 0 -0.0026 16 0 0 0 6.01E+07 3.72E+07 - - - 6.781 1 221125_WJC_METTL3_EV_vs_WT_F04.20060.20060.3 9.87E-10 18/76 K.LIEAEDNMNC[160.03]QMSNITVTYR.D "sp|P62318|SMD3_HUMAN,tr|H3BT13|H3BT13_HUMAN" 2 2401.0712 2.55 53278 20060 3 2401.071519 801.3643 Small nuclear ribonucleoprotein Sm D3 OS=Homo sapiens OX=9606 GN=SNRPD3 PE=1 SV=1 4.14 3299.2 - 2.66E+06 - - - 0.1258 - 2.868 0.697 - 176.4 1 2 0 0.0003 20 0 0 0 3.14E+07 1.23E+07 - - - 8.8669 1 221125_WJC_METTL3_EV_vs_WT_F04.20061.20061.2 1.17E-13 21/30 F.ASFNDTFVHVTDLSGK.E "sp|P62263|RS14_HUMAN,tr|A0A2R8Y811|A0A2R8Y811_HUMAN,tr|E5RH77|E5RH77_HUMAN" 3 1736.837 2.4 53279 20061 2 1736.828211 869.4258 40S ribosomal protein S14 OS=Homo sapiens OX=9606 GN=RPS14 PE=1 SV=3 5.21 3299.3 - 1.49E+06 - - - -5.0396 - 3.997 0.736 - 1386.5 1 1 0 -0.0088 16 0 0 0 3.82E+07 1.59E+07 - - - 7.8808 1 221125_WJC_METTL3_EV_vs_WT_F04.20066.20066.3 2.49E-06 16/60 R.EVIDLLK[136.11]PDQVEGIQK[136.11].S sp|Q86UP2|KTN1_HUMAN 1 1839.0324 1.62 53282 20066 3 1839.028261 614.0181 Kinectin OS=Homo sapiens OX=9606 GN=KTN1 PE=1 SV=1 4.32 3299.8 - 3.13E+06 - - - -2.267 - 2.9 0.546 - 233.2 1 2 0 -0.0042 16 0 0 0 6.00E+07 3.70E+07 - - - 7.3581 1 221125_WJC_METTL3_EV_vs_WT_F04.20068.20068.4 1.92E-09 21/84 R.EVPIPEHIDIYHLTR.E "sp|Q9UG63|ABCF2_HUMAN,tr|C9JZV3|C9JZV3_HUMAN,tr|C9JHK9|C9JHK9_HUMAN" 3 1830.9628 0.65 53284 20068 4 1830.959461 458.748 ATP-binding cassette sub-family F member 2 OS=Homo sapiens OX=9606 GN=ABCF2 PE=1 SV=2 5.28 3300.1 - 986563 - - - -1.8422 - 3.957 0.64 - 412.1 1 2 0 -0.0034 15 0 0 0 3.15E+07 4.82E+07 - - - 5.2878 1 221125_WJC_METTL3_EV_vs_WT_F04.20071.20071.3 1.98E-09 19/64 R.TENPVIMGLSSQNGQLR[166.11].G "sp|P26196|DDX6_HUMAN,tr|Q8IV96|Q8IV96_HUMAN" 2 1852.9341 1.2 53285 20071 3 1852.928433 618.652 Probable ATP-dependent RNA helicase DDX6 OS=Homo sapiens OX=9606 GN=DDX6 PE=1 SV=2 5.66 3300.5 - 1.34E+06 - - - -3.04 - 3.392 0.581 - 556.7 1 2 0 -0.0056 17 0 0 0 3.83E+07 3.19E+07 - - - 8.1017 1 221125_WJC_METTL3_EV_vs_WT_F04.20072.20072.2 1.22E-13 19/36 K.QNLYDLDEDDDGIASVPTK.Q "sp|Q9BY77|PDIP3_HUMAN,tr|F6VRR5|F6VRR5_HUMAN,tr|F8WCX5|F8WCX5_HUMAN,tr|Q8WUT1|Q8WUT1_HUMAN,tr|F8WEE2|F8WEE2_HUMAN" 5 2106.9593 1.65 53286 20072 2 2106.957449 1054.4869 Polymerase delta-interacting protein 3 OS=Homo sapiens OX=9606 GN=POLDIP3 PE=1 SV=2 3.61 3300.7 - 1.62E+06 - - - -0.8899 - 3.956 0.71 - 714.4 1 2 0 -0.0019 19 0 0 0 3.94E+08 2.39E+08 - - - 7.6655 1 221125_WJC_METTL3_EV_vs_WT_F04.20073.20073.3 2.93E-11 15/72 K.QNLYDLDEDDDGIASVPTK.Q "sp|Q9BY77|PDIP3_HUMAN,tr|F6VRR5|F6VRR5_HUMAN,tr|F8WCX5|F8WCX5_HUMAN,tr|Q8WUT1|Q8WUT1_HUMAN,tr|F8WEE2|F8WEE2_HUMAN" 5 2106.9593 1.75 53287 20073 3 2106.963584 703.3271 Polymerase delta-interacting protein 3 OS=Homo sapiens OX=9606 GN=POLDIP3 PE=1 SV=2 3.61 3300.7 - 2.31E+06 - - - 2.0219 - 3.442 0.676 - 186.5 1 2 0 0.0043 19 0 0 0 3.43E+08 1.96E+08 - - - 9.1123 1 221125_WJC_METTL3_EV_vs_WT_F04.20075.20075.2 1.37E-13 18/36 K.QNLYDLDEDDDGIASVPTK[136.11].Q "sp|Q9BY77|PDIP3_HUMAN,tr|F6VRR5|F6VRR5_HUMAN,tr|F8WCX5|F8WCX5_HUMAN,tr|Q8WUT1|Q8WUT1_HUMAN,tr|F8WEE2|F8WEE2_HUMAN" 5 2114.9735 1.65 53289 20075 2 2114.967176 1058.494 Polymerase delta-interacting protein 3 OS=Homo sapiens OX=9606 GN=POLDIP3 PE=1 SV=2 3.61 3301 - 1.59E+06 - - - -3.0015 - 3.678 0.741 - 643.1 1 2 0 -0.0063 19 0 0 0 3.94E+08 2.39E+08 - - - 7.714 1 221125_WJC_METTL3_EV_vs_WT_F04.20076.20076.3 0.00122 25/64 K.QGGLGPMNIPLVSDPK[136.11]R[166.11].T "sp|Q06830|PRDX1_HUMAN,tr|A0A0A0MSI0|A0A0A0MSI0_HUMAN" 2 1795.9734 0.38 53290 20076 3 1795.975401 599.6651 Peroxiredoxin-1 OS=Homo sapiens OX=9606 GN=PRDX1 PE=1 SV=1 8.75 3301.1 - 1.44E+06 - - - 1.137 - 3.591 0.56 - 668.6 1 2 0 0.002 17 0 0 0 1.06E+07 2.79E+07 - - - 8.0126 0.9998 221125_WJC_METTL3_EV_vs_WT_F04.20078.20078.3 0.000109 Nov-48 R.SIFQHIQSAQSQR.S "sp|Q9Y2W1|TR150_HUMAN,tr|A0A3B3ITZ9|A0A3B3ITZ9_HUMAN" 2 1528.7746 2.8 53292 20078 3 1528.772893 510.5988 Thyroid hormone receptor-associated protein 3 OS=Homo sapiens OX=9606 GN=THRAP3 PE=1 SV=2 9.49 3301.4 - 703750 - - - -1.1421 - 1.88 0.404 - 91.3 1 2 0 -0.0017 13 0 0 0 5.55E+06 1.99E+06 - - - 4.7553 1 221125_WJC_METTL3_EV_vs_WT_F04.20081.20081.3 3.86E-09 18/68 R.QIENLQATLGSQTSSWEK.L "sp|P82094|TMF1_HUMAN,tr|A0A2R8Y7M0|A0A2R8Y7M0_HUMAN" 2 2018.9909 1.86 53294 20081 3 2018.986613 674.0042 TATA element modulatory factor OS=Homo sapiens OX=9606 GN=TMF1 PE=1 SV=2 4.53 3301.7 - 1.77E+06 - - - -2.1228 - 3.939 0.592 - 456.3 1 2 0 -0.0043 18 0 0 0 3.78E+07 2.03E+07 - - - 8.5528 0.997 221125_WJC_METTL3_EV_vs_WT_F04.20083.20083.4 3.38E-06 17/90 R.SPSELFAQHIVTIVHH.V "sp|Q9Y2W1|TR150_HUMAN,tr|A0A3B3ITZ9|A0A3B3ITZ9_HUMAN" 2 1813.9475 - 53295 20083 4 1813.94381 454.4942 Thyroid hormone receptor-associated protein 3 OS=Homo sapiens OX=9606 GN=THRAP3 PE=1 SV=2 6.2 3301.9 - 2.54E+06 - - - -2.0442 - 3.218 0.577 - 198.6 1 1 0 -0.0037 16 0 0 0 - - - - - 4.6589 0.9988 221125_WJC_METTL3_EV_vs_WT_F04.20084.20084.3 7.63E-10 15/60 R.SPSELFAQHIVTIVHH.V "sp|Q9Y2W1|TR150_HUMAN,tr|A0A3B3ITZ9|A0A3B3ITZ9_HUMAN" 2 1813.9475 - 53296 20084 3 1813.947108 605.6564 Thyroid hormone receptor-associated protein 3 OS=Homo sapiens OX=9606 GN=THRAP3 PE=1 SV=2 6.2 3302 - 1.20E+06 - - - -0.226 - 3.084 0.595 - 214.2 1 1 0 -0.0004 16 0 0 0 - - - - - 8.0633 1 221125_WJC_METTL3_EV_vs_WT_F04.20086.20086.3 1.19E-08 16/64 K.NAFYIGSYQQC[160.03]INEAQR[166.11].V "sp|O14579|COPE_HUMAN,tr|M0QXB4|M0QXB4_HUMAN,tr|M0R061|M0R061_HUMAN" 3 2070.9457 1.15 53298 20086 3 2070.944727 691.3225 Coatomer subunit epsilon OS=Homo sapiens OX=9606 GN=COPE PE=1 SV=3 5.99 3302.2 - 1.42E+06 - - - -0.4669 - 3.198 0.564 - 356.2 1 2 0 -0.001 17 0 0 0 1.88E+07 1.63E+07 - - - 7.7647 0.9998 221125_WJC_METTL3_EV_vs_WT_F04.20088.20088.2 7.87E-07 24-Dec R.FSGSGSGTDFTLK.L "sp|A2NJV5|KV229_HUMAN,sp|A0A087WW87|KV240_HUMAN,sp|P06310|KV230_HUMAN,sp|A0A075B6S2|KVD29_HUMAN,sp|P01614|KVD40_HUMAN,sp|P01615|KVD28_HUMAN,sp|A0A075B6S6|KVD30_HUMAN,sp|A0A075B6P5|KV228_HUMAN,sp|A0A0A0MRZ7|KVD26_HUMAN" 9 1302.6092 21.42 53300 20088 2 1302.607524 652.3119 Immunoglobulin kappa variable 2-29 OS=Homo sapiens OX=9606 GN=IGKV2-29 PE=3 SV=2 5.84 3302.4 - 1.08E+06 - - - -1.2836 - 2.332 0.421 - 251.5 1 2 0 -0.0017 13 0 0 0 2.95E+07 1.38E+06 - - - 4.3231 0.9996 221125_WJC_METTL3_EV_vs_WT_F04.20089.20089.3 0.102 Jul-64 R.ALSMYEEAFQNTSDSDR.Y "sp|P52948|NUP98_HUMAN,tr|H7C3P6|H7C3P6_HUMAN,tr|H0YDF4|H0YDF4_HUMAN" 3 1962.8265 8.56 53301 20089 3 1962.827598 655.2828 Nuclear pore complex protein Nup98-Nup96 OS=Homo sapiens OX=9606 GN=NUP98 PE=1 SV=4 3.92 3302.6 - 686758 - - - 0.5411 - 1.663 0.375 - 52 1 2 0 0.0011 17 0 0 0 3.03E+06 3.54E+05 - - - 4.0055 0.9996 221125_WJC_METTL3_EV_vs_WT_F04.20090.20090.3 1.26 18/52 K.ILLAELEQLKGQGK.S "sp|P08670|VIME_HUMAN,tr|B0YJC4|B0YJC4_HUMAN,tr|A0A1B0GTT5|A0A1B0GTT5_HUMAN" 3 1538.9032 1.63 53302 20090 3 1538.898841 513.975 Vimentin OS=Homo sapiens OX=9606 GN=VIM PE=1 SV=4 6.14 3302.7 - 642642 - - - -2.8286 - 3.282 0.444 - 455.2 1 2 1 -0.0044 14 0 0 0 4.54E+07 2.78E+07 - - - 6.6473 1 221125_WJC_METTL3_EV_vs_WT_F04.20091.20091.2 8.35E-06 19/32 R.TENPVIMGLSSQNGQLR.G "sp|P26196|DDX6_HUMAN,tr|Q8IV96|Q8IV96_HUMAN" 2 1842.9258 1.89 53303 20091 2 1842.921903 922.4702 Probable ATP-dependent RNA helicase DDX6 OS=Homo sapiens OX=9606 GN=DDX6 PE=1 SV=2 5.66 3302.8 - 621862 - - - -2.1124 - 3.577 0.628 - 1042.2 1 2 0 -0.0039 17 0 0 0 1.35E+07 7.10E+06 - - - 6.8117 1 221125_WJC_METTL3_EV_vs_WT_F04.20092.20092.2 6.42E-10 17/34 R.QIENLQATLGSQTSSWEK.L "sp|P82094|TMF1_HUMAN,tr|A0A2R8Y7M0|A0A2R8Y7M0_HUMAN" 2 2018.9909 1.82 53304 20092 2 2018.990459 1010.5027 TATA element modulatory factor OS=Homo sapiens OX=9606 GN=TMF1 PE=1 SV=2 4.53 3303 - 513642 - - - -0.2179 - 3.309 0.653 - 932.4 1 2 0 -0.0004 18 0 0 0 1.25E+07 6.87E+06 - - - 6.8059 0.9999 221125_WJC_METTL3_EV_vs_WT_F04.20095.20095.2 1.46E-07 26-Nov K.GGSTTGSQFLEQFK[136.11].T "sp|Q14157|UBP2L_HUMAN,tr|F8W726|F8W726_HUMAN" 2 1493.7242 2.08 53305 20095 2 1493.722516 747.8694 Ubiquitin-associated protein 2-like OS=Homo sapiens OX=9606 GN=UBAP2L PE=1 SV=2 6 3303.4 - 6.49E+06 - - - -1.1093 - 2.565 0.473 - 444.4 1 2 0 -0.0017 14 0 0 0 1.18E+09 5.69E+08 - - - 4.8979 1 221125_WJC_METTL3_EV_vs_WT_F04.20097.20097.2 1.88E-05 13/26 K.GGSTTGSQFLEQFK.T "sp|Q14157|UBP2L_HUMAN,tr|F8W726|F8W726_HUMAN" 2 1485.71 2.08 53307 20097 2 1485.708584 743.8623 Ubiquitin-associated protein 2-like OS=Homo sapiens OX=9606 GN=UBAP2L PE=1 SV=2 6 3303.5 - 1.08E+07 - - - -0.9349 - 2.854 0.58 - 773.4 1 2 0 -0.0014 14 0 0 0 1.18E+09 5.69E+08 - - - 5.9562 0.9998 221125_WJC_METTL3_EV_vs_WT_F04.20099.20099.3 0.0011 Nov-52 K.GGSTTGSQFLEQFK.T "sp|Q14157|UBP2L_HUMAN,tr|F8W726|F8W726_HUMAN" 2 1485.71 2.49 53309 20099 3 1485.707522 496.2439 Ubiquitin-associated protein 2-like OS=Homo sapiens OX=9606 GN=UBAP2L PE=1 SV=2 6 3303.7 - 1.42E+06 - - - -1.6497 - 2.061 0.396 - 115.3 1 2 0 -0.0025 14 0 0 0 1.13E+08 4.53E+07 - - - 4.8762 0.9998 221125_WJC_METTL3_EV_vs_WT_F04.20101.20101.2 3.41E-07 22-Dec R.GYISPYFINTSK.G "sp|P10809|CH60_HUMAN,tr|A0A7I2V2X6|A0A7I2V2X6_HUMAN,tr|A0A7I2V599|A0A7I2V599_HUMAN,tr|A0A7I2YQ71|A0A7I2YQ71_HUMAN,tr|E7ESH4|E7ESH4_HUMAN,tr|A0A7I2V5M1|A0A7I2V5M1_HUMAN,tr|A0A7I2V5K3|A0A7I2V5K3_HUMAN,tr|A0A7I2V369|A0A7I2V369_HUMAN" 8 1388.6976 1.65 53311 20101 2 1388.695196 695.3561 "60 kDa heat shock protein, mitochondrial OS=Homo sapiens OX=9606 GN=HSPD1 PE=1 SV=2" 8.5 3303.9 - 909840 - - - -1.7434 - 2.491 0.536 - 590.6 1 2 0 -0.0024 12 0 0 0 5.29E+07 3.20E+07 - - - 5.4006 0.9998 221125_WJC_METTL3_EV_vs_WT_F04.20103.20103.3 2.14E-05 15/56 R.VK[136.11]EDENVPFLLVGNK[136.11].S "sp|P11233|RALA_HUMAN,tr|H7C3P7|H7C3P7_HUMAN" 2 1715.9429 1.14 53313 20103 3 1715.938643 572.9882 Ras-related protein Ral-A OS=Homo sapiens OX=9606 GN=RALA PE=1 SV=1 4.68 3304.1 - 835679 - - - -2.4727 - 2.94 0.547 - 311.9 1 2 1 -0.0042 15 0 0 0 4.40E+07 3.85E+07 - - - 7.4513 0.9997 221125_WJC_METTL3_EV_vs_WT_F04.20104.20104.3 0.000192 Nov-52 K.GGSTTGSQFLEQFK[136.11].T "sp|Q14157|UBP2L_HUMAN,tr|F8W726|F8W726_HUMAN" 2 1493.7242 2.46 53314 20104 3 1493.721359 498.9153 Ubiquitin-associated protein 2-like OS=Homo sapiens OX=9606 GN=UBAP2L PE=1 SV=2 6 3304.3 - 831309 - - - -1.8839 - 1.945 0.4 - 102.8 1 2 0 -0.0028 14 0 0 0 1.11E+08 4.53E+07 - - - 4.7668 1 221125_WJC_METTL3_EV_vs_WT_F04.20105.20105.2 1.97E-08 16/34 R.QIENLQATLGSQTSSWEK[136.11].L "sp|P82094|TMF1_HUMAN,tr|A0A2R8Y7M0|A0A2R8Y7M0_HUMAN" 2 2027.0051 1.82 53315 20105 2 2027.001271 1014.5098 TATA element modulatory factor OS=Homo sapiens OX=9606 GN=TMF1 PE=1 SV=2 4.53 3304.4 - 684663 - - - -1.8885 - 3.302 0.602 - 728.8 1 2 0 -0.0038 18 0 0 0 1.25E+07 6.87E+06 - - - 6.423 1 221125_WJC_METTL3_EV_vs_WT_F04.20106.20106.2 1.73E-09 19/30 Q.TQISETNVILSMDNNR.S sp|P04264|K2C1_HUMAN 1 1833.8891 999 53316 20106 2 1833.889035 917.9518 "Keratin, type II cytoskeletal 1 OS=Homo sapiens OX=9606 GN=KRT1 PE=1 SV=6" 4.37 3304.5 - 638244 - - - -0.0224 - 3.527 0.671 - 1040.9 1 1 0 0 16 0 0 0 2.54E+07 0.00E+00 - - - 7.0959 0.9043 221125_WJC_METTL3_EV_vs_WT_F04.20109.20109.2 1.08E-07 13/20 L.FQHIQSAQSQR.S "sp|Q9Y2W1|TR150_HUMAN,tr|A0A3B3ITZ9|A0A3B3ITZ9_HUMAN" 2 1328.6585 2.01 53319 20109 2 1328.65362 665.3365 Thyroid hormone receptor-associated protein 3 OS=Homo sapiens OX=9606 GN=THRAP3 PE=1 SV=2 9.76 3304.9 - 566415 - - - -3.7075 - 2.034 0.395 - 746.9 1 1 0 -0.0049 11 0 0 0 8.48E+06 4.22E+06 - - - 3.8777 1 221125_WJC_METTL3_EV_vs_WT_F04.20111.20111.2 1.05E-10 14/32 K.NAFYIGSYQQC[160.03]INEAQR[166.11].V "sp|O14579|COPE_HUMAN,tr|M0QXB4|M0QXB4_HUMAN,tr|M0R061|M0R061_HUMAN" 3 2070.9457 0.74 53321 20111 2 2070.942989 1036.4801 Coatomer subunit epsilon OS=Homo sapiens OX=9606 GN=COPE PE=1 SV=3 5.99 3305.2 - 362582 - - - -1.3062 - 3.032 0.717 - 534.5 1 2 0 -0.0027 17 0 0 0 2.43E+06 3.30E+06 - - - 7.063 0.9999 221125_WJC_METTL3_EV_vs_WT_F04.20116.20116.3 1.46E-05 16/52 K.ILLAELEQLK[136.11]GQGK[136.11].S "sp|P08670|VIME_HUMAN,tr|B0YJC4|B0YJC4_HUMAN,tr|A0A1B0GTT5|A0A1B0GTT5_HUMAN" 3 1554.9316 1.63 53325 20116 3 1554.930946 519.3178 Vimentin OS=Homo sapiens OX=9606 GN=VIM PE=1 SV=4 6.14 3305.6 - 2.88E+06 - - - -0.4161 - 3.2 0.493 - 337.9 1 2 1 -0.0006 14 0 0 0 4.54E+07 2.78E+07 - - - 7.1274 1 221125_WJC_METTL3_EV_vs_WT_F04.20117.20117.3 7.38E-10 17/56 R.VKEDENVPFLLVGNK.S "sp|P11233|RALA_HUMAN,tr|H7C3P7|H7C3P7_HUMAN" 2 1699.9145 1.14 53326 20117 3 1699.914242 567.6454 Ras-related protein Ral-A OS=Homo sapiens OX=9606 GN=RALA PE=1 SV=1 4.68 3305.7 - 2.38E+06 - - - -0.1435 - 2.96 0.611 - 513.9 1 2 1 -0.0002 15 0 0 0 4.40E+07 3.85E+07 - - - 8.1836 1 221125_WJC_METTL3_EV_vs_WT_F04.20118.20118.2 1.96E-08 22-Dec R.GYISPYFINTSK[136.11].G "sp|P10809|CH60_HUMAN,tr|A0A7I2V2X6|A0A7I2V2X6_HUMAN,tr|A0A7I2V599|A0A7I2V599_HUMAN,tr|A0A7I2YQ71|A0A7I2YQ71_HUMAN,tr|E7ESH4|E7ESH4_HUMAN,tr|A0A7I2V5M1|A0A7I2V5M1_HUMAN,tr|A0A7I2V5K3|A0A7I2V5K3_HUMAN,tr|A0A7I2V369|A0A7I2V369_HUMAN" 8 1396.7118 1.58 53327 20118 2 1396.712218 699.3632 "60 kDa heat shock protein, mitochondrial OS=Homo sapiens OX=9606 GN=HSPD1 PE=1 SV=2" 8.5 3305.8 - 2.04E+06 - - - 0.2871 - 2.514 0.59 - 526.5 1 2 0 0.0004 12 0 0 0 4.98E+07 3.15E+07 - - - 5.8242 0.9982 221125_WJC_METTL3_EV_vs_WT_F04.20120.20120.3 8.01E-09 14/60 Q.TQISETNVILSMDNNR.S sp|P04264|K2C1_HUMAN 1 1833.8891 434.38 53329 20120 3 1833.888476 612.3036 "Keratin, type II cytoskeletal 1 OS=Homo sapiens OX=9606 GN=KRT1 PE=1 SV=6" 4.37 3305.9 - 1.47E+06 - - - -0.3272 - 2.569 0.567 - 304.9 1 1 0 -0.0006 16 0 0 0 7.96E+07 1.83E+05 - - - 7.2823 0.9999 221125_WJC_METTL3_EV_vs_WT_F04.20122.20122.3 0.000345 Dec-52 R.K[136.11]GISLNPEQWSQLK[136.11].E sp|P53999|TCP4_HUMAN 1 1642.9014 0.47 53331 20122 3 1642.902138 548.6411 Activated RNA polymerase II transcriptional coactivator p15 OS=Homo sapiens OX=9606 GN=SUB1 PE=1 SV=3 8.59 3306.1 - 740388 - - - 0.476 - 2.134 0.422 - 175.6 1 2 0 0.0008 14 0 0 0 3.87E+06 8.30E+06 - - - 5.2591 0.9998 221125_WJC_METTL3_EV_vs_WT_F04.20123.20123.3 0.00094 14/52 K.HFC[160.03]PNVPIILVGNK.K "sp|P61586|RHOA_HUMAN,sp|P08134|RHOC_HUMAN,tr|E9PQH6|E9PQH6_HUMAN,tr|C9JNR4|C9JNR4_HUMAN,tr|A0A7I2V3G1|A0A7I2V3G1_HUMAN,tr|Q5JR08|Q5JR08_HUMAN,tr|C9JX21|C9JX21_HUMAN,tr|Q5JR05|Q5JR05_HUMAN,tr|Q5JR07|Q5JR07_HUMAN" 9 1606.8654 1.2 53332 20123 3 1606.864643 536.6291 Transforming protein RhoA OS=Homo sapiens OX=9606 GN=RHOA PE=1 SV=1 8.23 3306.3 - 515475 - - - -0.4512 - 2.191 0.342 - 192.4 1 2 0 -0.0007 14 0 0 0 5.90E+06 4.91E+06 - - - 4.4372 0.9999 221125_WJC_METTL3_EV_vs_WT_F04.20129.20129.3 1.86E-06 18/64 K.QGGLGPMNIPLVSDPKR.T "sp|Q06830|PRDX1_HUMAN,tr|A0A0A0MSI0|A0A0A0MSI0_HUMAN" 2 1777.9509 0.38 53336 20129 3 1777.947806 593.6576 Peroxiredoxin-1 OS=Homo sapiens OX=9606 GN=PRDX1 PE=1 SV=1 8.75 3306.9 - 873669 - - - -1.734 - 2.674 0.433 - 291.6 1 2 0 -0.0031 17 0 0 0 1.06E+07 2.79E+07 - - - 5.8515 1 221125_WJC_METTL3_EV_vs_WT_F04.20130.20130.3 3.37E-08 Dec-68 K.RVEDAYILTC[160.03]NVSLEYEK.T sp|P40227|TCPZ_HUMAN 1 2201.0674 0.48 53337 20130 3 2201.065489 734.6964 T-complex protein 1 subunit zeta OS=Homo sapiens OX=9606 GN=CCT6A PE=1 SV=3 4.41 3307 - 1.51E+06 - - - -0.8841 - 3.044 0.599 - 165.7 1 2 0 -0.0019 18 0 0 0 2.59E+07 5.46E+07 - - - 7.9896 1 221125_WJC_METTL3_EV_vs_WT_F04.20131.20131.3 1.45E-07 16/60 R.EVPNTVHQFQLDITVK.M "sp|P56556|NDUA6_HUMAN,tr|A0A2Y9D025|A0A2Y9D025_HUMAN" 2 1866.984 2.03 53338 20131 3 1866.985538 623.3353 NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 6 OS=Homo sapiens OX=9606 GN=NDUFA6 PE=1 SV=4 5.32 3307.1 - 974470 - - - 0.8436 - 3.291 0.566 - 229.1 1 2 0 0.0016 16 0 0 0 3.44E+07 1.69E+07 - - - 7.9063 1 221125_WJC_METTL3_EV_vs_WT_F04.20133.20133.3 3.83E-06 20/68 K.TANFVAVDTELSGLGDRK.S sp|Q96GM8|TOE1_HUMAN 1 1891.964 0.89 53340 20133 3 1891.962404 631.6619 Target of EGR1 protein 1 OS=Homo sapiens OX=9606 GN=TOE1 PE=1 SV=1 4.56 3307.3 - 844033 - - - -0.8203 - 3.91 0.569 - 469.7 1 2 0 -0.0016 18 0 0 0 8.43E+06 9.45E+06 - - - 8.2787 0.9999 221125_WJC_METTL3_EV_vs_WT_F04.20134.20134.3 0.000341 Dec-80 R.LPPYPYSSPSLVLPTQPHTPK.S "sp|Q53ET0|CRTC2_HUMAN,tr|Q5T4K5|Q5T4K5_HUMAN,tr|H0YDQ8|H0YDQ8_HUMAN" 3 2318.2311 1.58 53341 20134 3 2318.230013 773.751 CREB-regulated transcription coactivator 2 OS=Homo sapiens OX=9606 GN=CRTC2 PE=1 SV=2 8.5 3307.4 - 663221 - - - -0.456 - 2.417 0.415 - 100.1 1 2 0 -0.0011 21 0 0 0 3.42E+06 2.16E+06 - - - 5.2824 1 221125_WJC_METTL3_EV_vs_WT_F04.20141.20141.2 4.13E-08 15/28 K.TADVTSLFGGEDTSR.S sp|O00443|P3C2A_HUMAN 1 1554.7162 1.42 53346 20141 2 1554.708234 778.3654 Phosphatidylinositol 4-phosphate 3-kinase C2 domain-containing subunit alpha OS=Homo sapiens OX=9606 GN=PIK3C2A PE=1 SV=2 4.03 3308.2 - 1.96E+06 - - - -5.1115 - 3.143 0.668 - 767.6 1 2 0 -0.0079 15 0 0 0 5.46E+07 3.84E+07 - - - 6.7878 0.9985 221125_WJC_METTL3_EV_vs_WT_F04.20143.20143.3 6.74E-07 15/64 M.QTQISETNVILSMDNNR.S sp|P04264|K2C1_HUMAN 1 1961.9477 999 53348 20143 3 1961.948739 654.9898 "Keratin, type II cytoskeletal 1 OS=Homo sapiens OX=9606 GN=KRT1 PE=1 SV=6" 4.37 3308.3 - 2.62E+06 - - - 0.553 - 2.876 0.569 - 287.3 1 1 0 0.0011 17 0 0 0 1.01E+08 0.00E+00 - - - 7.5523 1 221125_WJC_METTL3_EV_vs_WT_F04.20144.20144.2 4.61E-11 20/32 M.QTQISETNVILSMDNNR.S sp|P04264|K2C1_HUMAN 1 1961.9477 999 53349 20144 2 1961.948983 981.9811 "Keratin, type II cytoskeletal 1 OS=Homo sapiens OX=9606 GN=KRT1 PE=1 SV=6" 4.37 3308.4 - 1.28E+06 - - - 0.6774 - 3.692 0.709 - 1608.2 1 1 0 0.0013 17 0 0 0 6.56E+07 0.00E+00 - - - 7.4885 1 221125_WJC_METTL3_EV_vs_WT_F04.20145.20145.3 3.40E-06 17/48 K.TYEQVLENLESKR.F sp|Q16762|THTR_HUMAN 1 1607.8155 1.77 53350 20145 3 1607.811418 536.9458 Thiosulfate sulfurtransferase OS=Homo sapiens OX=9606 GN=TST PE=1 SV=4 4.78 3308.6 - 1.17E+06 - - - -2.5395 - 2.765 0.554 - 294.4 1 2 0 -0.0041 13 0 0 0 2.78E+07 1.57E+07 - - - 7.4729 1 221125_WJC_METTL3_EV_vs_WT_F04.20146.20146.4 1.45E-06 23/132 R.FKPAYNPYTEPSMEVFSYHQGLK.K "sp|Q9Y285|SYFA_HUMAN,tr|K7EPH2|K7EPH2_HUMAN,tr|K7ER00|K7ER00_HUMAN" 3 2732.2945 1.86 53351 20146 4 2732.301561 684.0809 Phenylalanine--tRNA ligase alpha subunit OS=Homo sapiens OX=9606 GN=FARSA PE=1 SV=3 6.75 3308.7 - 1.11E+06 - - - 2.5934 - 4.073 0.567 - 364 1 2 0 0.0071 23 0 0 0 8.15E+06 4.38E+06 - - - 4.6142 0.9861 221125_WJC_METTL3_EV_vs_WT_F04.20149.20149.2 0.23 26-Nov K.ILLAELEQLKGQGK.S "sp|P08670|VIME_HUMAN,tr|B0YJC4|B0YJC4_HUMAN,tr|A0A1B0GTT5|A0A1B0GTT5_HUMAN" 3 1538.9032 4.63 53354 20149 2 1538.901593 770.4589 Vimentin OS=Homo sapiens OX=9606 GN=VIM PE=1 SV=4 6.14 3309.1 - 627152 - - - -1.0404 - 1.484 0.313 - 153.9 1 2 1 -0.0016 14 0 0 0 4.00E+06 8.63E+05 - - - 2.3429 1 221125_WJC_METTL3_EV_vs_WT_F04.20150.20150.3 7.35E-08 18/60 R.EVPNTVHQFQLDITVK[136.11].M "sp|P56556|NDUA6_HUMAN,tr|A0A2Y9D025|A0A2Y9D025_HUMAN" 2 1874.9982 2.03 53355 20150 3 1874.999861 626.0067 NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 6 OS=Homo sapiens OX=9606 GN=NDUFA6 PE=1 SV=4 5.32 3309.2 - 560910 - - - 0.9056 - 3.262 0.554 - 262.1 1 2 0 0.0017 16 0 0 0 3.44E+07 1.69E+07 - - - 7.7498 0.9225 221125_WJC_METTL3_EV_vs_WT_F04.20151.20151.2 0.0947 Aug-34 K.QSKPVTTPEEIAQVATIS.A "sp|P10809|CH60_HUMAN,tr|A0A7I2V599|A0A7I2V599_HUMAN,tr|E7EXB4|E7EXB4_HUMAN,tr|A0A7I2YQ71|A0A7I2YQ71_HUMAN,tr|E7ESH4|E7ESH4_HUMAN,tr|A0A7I2V5M1|A0A7I2V5M1_HUMAN,tr|A0A7I2V5K3|A0A7I2V5K3_HUMAN,tr|A0A7I2V369|A0A7I2V369_HUMAN" 8 1897.9997 1.48 53356 20151 2 1897.997002 950.0071 "60 kDa heat shock protein, mitochondrial OS=Homo sapiens OX=9606 GN=HSPD1 PE=1 SV=2" 4.53 3309.3 - 559860 - - - -1.4073 - 1.657 0.307 - 135.4 2 1 0 -0.0027 18 0 0 0 3.24E+07 2.19E+07 - - - 2.4148 0.9999 221125_WJC_METTL3_EV_vs_WT_F04.20152.20152.4 3.24E-05 16/84 K.IWDILGDRPSLVHSR.D "sp|Q13610|PWP1_HUMAN,tr|B4DJV5|B4DJV5_HUMAN" 2 1762.9479 1.08 53357 20152 4 1762.948524 441.7442 Periodic tryptophan protein 1 homolog OS=Homo sapiens OX=9606 GN=PWP1 PE=1 SV=1 6.75 3309.5 - 520294 - - - 0.3812 - 2.792 0.441 - 212.2 1 2 0 0.0007 15 0 0 0 1.76E+07 1.63E+07 - - - 3.4317 1 221125_WJC_METTL3_EV_vs_WT_F04.20157.20157.2 4.39E-11 13/24 K.DFDFESANAQFNK.E "sp|Q8ND56|LS14A_HUMAN,tr|A0A140TA76|A0A140TA76_HUMAN,tr|K7EMZ9|K7EMZ9_HUMAN" 3 1531.6579 1.08 53360 20157 2 1531.656161 766.8362 Protein LSM14 homolog A OS=Homo sapiens OX=9606 GN=LSM14A PE=1 SV=3 4.03 3310 - 3.09E+06 - - - -1.1595 - 2.794 0.623 - 401.1 1 2 0 -0.0018 13 0 0 0 4.88E+08 4.52E+08 - - - 6.279 1 221125_WJC_METTL3_EV_vs_WT_F04.20158.20158.2 3.55E-10 17/28 K.TADVTSLFGGEDTSR[166.11].S sp|O00443|P3C2A_HUMAN 1 1564.7245 1.42 53361 20158 2 1564.726055 783.3695 Phosphatidylinositol 4-phosphate 3-kinase C2 domain-containing subunit alpha OS=Homo sapiens OX=9606 GN=PIK3C2A PE=1 SV=2 4.03 3310.1 - 2.61E+06 - - - 1.0251 - 3.117 0.662 - 1049.3 1 2 0 0.0016 15 0 0 0 5.46E+07 3.84E+07 - - - 6.7251 0.9999 221125_WJC_METTL3_EV_vs_WT_F04.20159.20159.3 1.54E-06 18/44 R.AR[166.11]FEELNADLFR[166.11].G "sp|P54652|HSP72_HUMAN,sp|P11142|HSP7C_HUMAN,tr|E9PNE6|E9PNE6_HUMAN,tr|A8K7Q2|A8K7Q2_HUMAN,tr|E9PKE3|E9PKE3_HUMAN,tr|E9PN89|E9PN89_HUMAN" 6 1499.7636 0.17 53362 20159 3 1499.760884 500.9285 Heat shock-related 70 kDa protein 2 OS=Homo sapiens OX=9606 GN=HSPA2 PE=1 SV=1 4.68 3310.2 - 1.78E+06 - - - -1.7889 - 3.127 0.507 - 618.3 1 2 1 -0.0027 12 0 0 0 7.01E+07 4.04E+08 - - - 7.3519 0.9836 221125_WJC_METTL3_EV_vs_WT_F04.20162.20162.2 0.327 Aug-38 R.LGEHNIEVLEGNEQFINAAK.L "sp|P07478|TRY2_HUMAN,sp|Q8NHM4|TRY6_HUMAN,sp|P07477|TRY1_HUMAN,tr|E7EQ64|E7EQ64_HUMAN,tr|A6XMV9|A6XMV9_HUMAN,tr|A0A0J9YYC8|A0A0J9YYC8_HUMAN,tr|A6XMV8|A6XMV8_HUMAN,tr|H0Y8D1|H0Y8D1_HUMAN" 8 2224.1124 999 53365 20162 2 2224.10939 1113.0635 Trypsin-2 OS=Homo sapiens OX=9606 GN=PRSS2 PE=1 SV=1 4.48 3310.5 - 1.35E+06 - - - -1.3583 - 1.433 0.081 - 124.6 1 2 0 -0.003 20 0 0 0 2.11E+08 0.00E+00 - - - 0.5228 1 221125_WJC_METTL3_EV_vs_WT_F04.20164.20164.3 1.04E-13 20/96 K.VVINNSTSYAGSQGPSASAYVTYIR[166.11].S sp|O95628|CNOT4_HUMAN 1 2614.2903 2.05 53367 20164 3 2614.283549 872.4374 CCR4-NOT transcription complex subunit 4 OS=Homo sapiens OX=9606 GN=CNOT4 PE=1 SV=3 8.47 3310.8 - 916963 - - - -2.5693 - 3.8 0.68 - 416.3 1 2 0 -0.0067 25 0 0 0 2.56E+07 1.25E+07 - - - 9.1908 1 221125_WJC_METTL3_EV_vs_WT_F04.20169.20169.3 6.01E-09 16/56 R.GFGFVYFQNHDAADK.A sp|Q13151|ROA0_HUMAN 1 1714.774 1.25 53370 20169 3 1714.773885 572.5986 Heterogeneous nuclear ribonucleoprotein A0 OS=Homo sapiens OX=9606 GN=HNRNPA0 PE=1 SV=1 5.21 3311.5 - 4.65E+06 - - - -0.0496 - 3.169 0.62 - 205.6 1 2 0 -0.0001 15 0 0 0 1.07E+08 8.53E+07 - - - 8.462 0.9999 221125_WJC_METTL3_EV_vs_WT_F04.20170.20170.3 4.79E-06 14/48 K.SQPERDWVLNEFR.S "sp|Q92841|DDX17_HUMAN,tr|A0A0U1RQJ0|A0A0U1RQJ0_HUMAN,tr|A0A5H1ZRQ2|A0A5H1ZRQ2_HUMAN,tr|A0A1X7SBZ2|A0A1X7SBZ2_HUMAN" 4 1674.8114 0.89 53371 20170 3 1674.811941 559.2777 Probable ATP-dependent RNA helicase DDX17 OS=Homo sapiens OX=9606 GN=DDX17 PE=1 SV=2 4.68 3311.5 - 3.65E+06 - - - 0.3123 - 2.682 0.507 - 219.9 1 2 1 0.0005 13 0 0 0 3.39E+07 3.80E+07 - - - 6.8673 0.9999 221125_WJC_METTL3_EV_vs_WT_F04.20172.20172.3 3.49E-06 Dec-48 K.SQPER[166.11]DWVLNEFR[166.11].S "sp|Q92841|DDX17_HUMAN,tr|A0A0U1RQJ0|A0A0U1RQJ0_HUMAN,tr|A0A5H1ZRQ2|A0A5H1ZRQ2_HUMAN,tr|A0A1X7SBZ2|A0A1X7SBZ2_HUMAN" 4 1694.828 0.89 53373 20172 3 1694.826765 565.9499 Probable ATP-dependent RNA helicase DDX17 OS=Homo sapiens OX=9606 GN=DDX17 PE=1 SV=2 4.68 3311.6 - 2.84E+06 - - - -0.7039 - 2.541 0.531 - 212.5 1 2 1 -0.0012 13 0 0 0 3.39E+07 3.83E+07 - - - 6.9882 0.9999 221125_WJC_METTL3_EV_vs_WT_F04.20173.20173.3 7.72E-07 20/60 R.NR[166.11]LENDGATALAEAFR[166.11].V sp|P46060|RAGP1_HUMAN 1 1766.8815 0.97 53374 20173 3 1766.881149 589.9678 Ran GTPase-activating protein 1 OS=Homo sapiens OX=9606 GN=RANGAP1 PE=1 SV=1 4.68 3311.8 - 1.50E+06 - - - -0.1709 - 3.502 0.516 - 610.4 1 2 1 -0.0003 16 0 0 0 3.53E+07 3.63E+07 - - - 7.5087 1 221125_WJC_METTL3_EV_vs_WT_F04.20174.20174.3 2.16E-07 17/48 K.TYEQVLENLESK[136.11]R[166.11].F sp|Q16762|THTR_HUMAN 1 1625.838 1.9 53375 20174 3 1625.836508 542.9533 Thiosulfate sulfurtransferase OS=Homo sapiens OX=9606 GN=TST PE=1 SV=4 4.78 3311.9 - 1.38E+06 - - - -0.8998 - 2.648 0.608 - 274.8 1 2 0 -0.0015 13 0 0 0 3.04E+07 1.60E+07 - - - 7.9585 0.9999 221125_WJC_METTL3_EV_vs_WT_F04.20175.20175.4 4.11E-05 16/84 K.IWDILGDR[166.11]PSLVHSR[166.11].D "sp|Q13610|PWP1_HUMAN,tr|B4DJV5|B4DJV5_HUMAN" 2 1782.9644 1.08 53376 20175 4 1782.963806 446.7484 Periodic tryptophan protein 1 homolog OS=Homo sapiens OX=9606 GN=PWP1 PE=1 SV=1 6.75 3312 - 1.05E+06 - - - -0.3287 - 2.431 0.404 - 203.9 1 2 0 -0.0006 15 0 0 0 1.76E+07 1.63E+07 - - - 3.0601 0.9782 221125_WJC_METTL3_EV_vs_WT_F04.20176.20176.2 0.00761 Nov-34 K.QSK[136.11]PVTTPEEIAQVATIS.A "sp|P10809|CH60_HUMAN,tr|A0A7I2V599|A0A7I2V599_HUMAN,tr|E7EXB4|E7EXB4_HUMAN,tr|A0A7I2YQ71|A0A7I2YQ71_HUMAN,tr|E7ESH4|E7ESH4_HUMAN,tr|A0A7I2V5M1|A0A7I2V5M1_HUMAN,tr|A0A7I2V5K3|A0A7I2V5K3_HUMAN,tr|A0A7I2V369|A0A7I2V369_HUMAN" 8 1906.0139 1.47 53377 20176 2 1906.011174 954.0142 "60 kDa heat shock protein, mitochondrial OS=Homo sapiens OX=9606 GN=HSPD1 PE=1 SV=2" 4.53 3312.1 - 870352 - - - -1.416 - 1.856 0.437 - 209.7 1 1 0 -0.0027 18 0 0 0 6.98E+07 4.76E+07 - - - 3.7883 0.9999 221125_WJC_METTL3_EV_vs_WT_F04.20178.20178.3 5.11E-07 Dec-48 K.DFDFESANAQFNK.E "sp|Q8ND56|LS14A_HUMAN,tr|A0A140TA76|A0A140TA76_HUMAN,tr|K7EMZ9|K7EMZ9_HUMAN" 3 1531.6579 1.09 53379 20178 3 1531.658891 511.5599 Protein LSM14 homolog A OS=Homo sapiens OX=9606 GN=LSM14A PE=1 SV=3 4.03 3312.4 - 742496 - - - 0.6229 - 1.94 0.49 - 152 1 2 0 0.001 13 0 0 0 3.24E+07 2.98E+07 - - - 5.7995 1 221125_WJC_METTL3_EV_vs_WT_F04.20182.20182.2 2.10E-11 17/28 K.AFLDALQNQAEASSK.L sp|Q12931|TRAP1_HUMAN 1 1591.7842 2.03 53381 20182 2 1591.780984 796.8994 "Heat shock protein 75 kDa, mitochondrial OS=Homo sapiens OX=9606 GN=TRAP1 PE=1 SV=3" 4.37 3312.9 - 2.50E+06 - - - -2.021 - 3.558 0.643 - 1038.8 1 2 0 -0.0032 15 0 0 0 9.63E+07 4.74E+07 - - - 6.9096 0.9998 221125_WJC_METTL3_EV_vs_WT_F04.20183.20183.3 8.12E-06 Nov-48 K.DFDFESANAQFNK[136.11].E "sp|Q8ND56|LS14A_HUMAN,tr|A0A140TA76|A0A140TA76_HUMAN,tr|K7EMZ9|K7EMZ9_HUMAN" 3 1539.6721 1.07 53382 20183 3 1539.676314 514.2313 Protein LSM14 homolog A OS=Homo sapiens OX=9606 GN=LSM14A PE=1 SV=3 4.03 3313 - 1.49E+06 - - - 2.7129 - 1.649 0.528 - 136.6 1 2 0 0.0042 13 0 0 0 3.24E+07 3.03E+07 - - - 5.7816 1 221125_WJC_METTL3_EV_vs_WT_F04.20190.20190.2 7.80E-06 24-Dec K.DFDFESANAQFNK[136.11].E "sp|Q8ND56|LS14A_HUMAN,tr|A0A140TA76|A0A140TA76_HUMAN,tr|K7EMZ9|K7EMZ9_HUMAN" 3 1539.6721 1.08 53387 20190 2 1539.667759 770.8433 Protein LSM14 homolog A OS=Homo sapiens OX=9606 GN=LSM14A PE=1 SV=3 4.03 3313.8 - 2.34E+07 - - - -2.8435 - 2.618 0.657 - 380.3 1 2 0 -0.0044 13 0 0 0 4.88E+08 4.52E+08 - - - 6.3623 0.9997 221125_WJC_METTL3_EV_vs_WT_F04.20192.20192.3 0.000186 Oct-44 R.ARFEELNADLFR.G "sp|P54652|HSP72_HUMAN,sp|P11142|HSP7C_HUMAN,tr|E9PNE6|E9PNE6_HUMAN,tr|A8K7Q2|A8K7Q2_HUMAN,tr|E9PKE3|E9PKE3_HUMAN,tr|E9PN89|E9PN89_HUMAN" 6 1479.747 0.18 53389 20192 3 1479.744771 494.2563 Heat shock-related 70 kDa protein 2 OS=Homo sapiens OX=9606 GN=HSPA2 PE=1 SV=1 4.68 3313.9 - 3.08E+06 - - - -1.5246 - 2.313 0.471 - 226.7 1 2 1 -0.0023 12 0 0 0 7.11E+07 4.05E+08 - - - 6.1149 1 221125_WJC_METTL3_EV_vs_WT_F04.20194.20194.2 1.55E-09 17/28 K.AFLDALQNQAEASSK[136.11].L sp|Q12931|TRAP1_HUMAN 1 1599.7984 2.03 53391 20194 2 1599.794525 800.9065 "Heat shock protein 75 kDa, mitochondrial OS=Homo sapiens OX=9606 GN=TRAP1 PE=1 SV=3" 4.37 3314.1 - 2.06E+06 - - - -2.4228 - 3.508 0.65 - 1048.3 1 2 0 -0.0039 15 0 0 0 9.63E+07 4.74E+07 - - - 6.9263 0.9847 221125_WJC_METTL3_EV_vs_WT_F04.20196.20196.3 1.47E-09 18/60 R.INEANQLMQYDQC[160.03]LTK[136.11].G "sp|Q86SF2|GALT7_HUMAN,tr|H0YAK0|H0YAK0_HUMAN,tr|H0YAH3|H0YAH3_HUMAN" 3 1975.9223 1.36 53393 20196 3 1976.912965 659.648 N-acetylgalactosaminyltransferase 7 OS=Homo sapiens OX=9606 GN=GALNT7 PE=1 SV=1 4.37 3314.4 - 887882 - - - 501.3694 - 3.356 0.581 - 624.8 1 2 0 0.9907 16 0 0 0 1.67E+07 1.23E+07 - - - 7.8498 1 221125_WJC_METTL3_EV_vs_WT_F04.20199.20199.3 1.74E-11 23/68 R.HDIAFVEFDNEVQAGAAR.D "sp|P09012|SNRPA_HUMAN,tr|M0R268|M0R268_HUMAN" 2 1987.9388 1.55 53394 20199 3 1987.936111 663.6535 U1 small nuclear ribonucleoprotein A OS=Homo sapiens OX=9606 GN=SNRPA PE=1 SV=3 4.31 3314.7 - 1.37E+06 - - - -1.3547 - 4.427 0.614 - 857.5 1 2 0 -0.0027 18 0 0 0 2.75E+07 1.77E+07 - - - 9.0893 1 221125_WJC_METTL3_EV_vs_WT_F04.20200.20200.3 0.00017 15/60 R.INEANQLMQYDQC[160.03]LTK.G "sp|Q86SF2|GALT7_HUMAN,tr|H0YAK0|H0YAK0_HUMAN,tr|H0YAH3|H0YAH3_HUMAN" 3 1967.9081 0.47 53395 20200 3 1967.90871 656.9766 N-acetylgalactosaminyltransferase 7 OS=Homo sapiens OX=9606 GN=GALNT7 PE=1 SV=1 4.37 3314.9 - 1.62E+06 - - - 0.311 - 3.272 0.467 - 364.5 1 2 0 0.0006 16 0 0 0 1.91E+07 4.02E+07 - - - 6.788 1 221125_WJC_METTL3_EV_vs_WT_F04.20201.20201.3 4.54E-08 17/56 R.GFGFVYFQNHDAADK[136.11].A sp|Q13151|ROA0_HUMAN 1 1722.7882 1.24 53396 20201 3 1722.784932 575.27 Heterogeneous nuclear ribonucleoprotein A0 OS=Homo sapiens OX=9606 GN=HNRNPA0 PE=1 SV=1 5.21 3314.9 - 5.51E+06 - - - -1.8795 - 2.796 0.556 - 278.2 1 2 0 -0.0032 15 0 0 0 1.07E+08 8.64E+07 - - - 7.4209 1 221125_WJC_METTL3_EV_vs_WT_F04.20202.20202.3 2.47E-08 25/60 R.NRLENDGATALAEAFR.V sp|P46060|RAGP1_HUMAN 1 1746.8649 0.97 53397 20202 3 1746.864139 583.2956 Ran GTPase-activating protein 1 OS=Homo sapiens OX=9606 GN=RANGAP1 PE=1 SV=1 4.68 3315 - 3.30E+06 - - - -0.4419 - 4.269 0.547 - 1093.3 1 2 1 -0.0008 16 0 0 0 3.52E+07 3.63E+07 - - - 8.3623 1 221125_WJC_METTL3_EV_vs_WT_F04.20203.20203.2 1.83E-05 18/26 K.QNLSELEQLNENLK.K "sp|Q15643|TRIPB_HUMAN,tr|H0YJ97|H0YJ97_HUMAN" 2 1670.8475 2.5 53398 20203 2 1670.845436 836.431 Thyroid receptor-interacting protein 11 OS=Homo sapiens OX=9606 GN=TRIP11 PE=1 SV=3 4.25 3315.1 - 2.36E+06 - - - -1.2527 - 3.556 0.564 - 1436.2 1 2 0 -0.0021 14 0 0 0 6.18E+07 2.47E+07 - - - 6.3896 0.9998 221125_WJC_METTL3_EV_vs_WT_F04.20205.20205.3 1.02E-05 22/60 R.GNSLTLIDLPGHESLR[166.11].L sp|Q9Y5M8|SRPRB_HUMAN 1 1730.9191 1.08 53400 20205 3 1730.916599 577.9803 Signal recognition particle receptor subunit beta OS=Homo sapiens OX=9606 GN=SRPRB PE=1 SV=3 5.32 3315.3 - 1.07E+06 - - - -1.4264 - 3.406 0.293 - 719.7 1 2 0 -0.0025 16 0 0 0 4.42E+07 4.08E+07 - - - 4.9505 0.9999 221125_WJC_METTL3_EV_vs_WT_F04.20206.20206.4 2.02E-08 22/96 R.KFGEAIGMGFPVKVPYR.K "sp|P78347|GTF2I_HUMAN,tr|A0A494C1K3|A0A494C1K3_HUMAN" 2 1895.0128 1.29 53401 20206 4 1895.010572 474.7605 General transcription factor II-I OS=Homo sapiens OX=9606 GN=GTF2I PE=1 SV=2 9.7 3315.5 - 1.06E+06 - - - -1.1551 - 2.979 0.567 - 441.5 1 2 1 -0.0022 17 0 0 0 1.97E+07 1.52E+07 - - - 4.5396 0.9997 221125_WJC_METTL3_EV_vs_WT_F04.20207.20207.3 1.65E-05 15/56 R.NK[136.11]EVTWEVLEGEVEK[136.11].E sp|P05455|LA_HUMAN 1 1803.9225 0.95 53402 20207 3 1803.919711 602.3148 Lupus La protein OS=Homo sapiens OX=9606 GN=SSB PE=1 SV=2 4.33 3315.6 - 668045 - - - -1.571 - 2.764 0.439 - 265.4 1 2 1 -0.0028 15 0 0 0 7.53E+06 7.93E+06 - - - 6.0865 1 221125_WJC_METTL3_EV_vs_WT_F04.20212.20212.3 5.88E-16 28/84 R.KDLYANTVLSGGTTMYPGIADR.M "sp|P63261|ACTG_HUMAN,sp|P60709|ACTB_HUMAN,tr|A0A804GS07|A0A804GS07_HUMAN,tr|E7EVS6|E7EVS6_HUMAN,tr|A0A6Q8PFE4|A0A6Q8PFE4_HUMAN,tr|A0A2R8Y793|A0A2R8Y793_HUMAN,tr|I3L4N8|I3L4N8_HUMAN" 7 2342.1576 0.96 53405 20212 3 2342.158287 781.7265 "Actin, cytoplasmic 2 OS=Homo sapiens OX=9606 GN=ACTG1 PE=1 SV=1" 5.96 3316.1 - 2.57E+06 - - - 0.2733 - 4.249 0.697 - 720.6 1 2 0 0.0006 22 0 0 0 1.07E+08 1.11E+08 - - - 9.7405 1 221125_WJC_METTL3_EV_vs_WT_F04.20213.20213.3 6.19E-09 15/76 K.RSSPAAFINPPIGTVTPALK.L "sp|Q9BY77|PDIP3_HUMAN,tr|F6VRR5|F6VRR5_HUMAN,tr|F8WCX5|F8WCX5_HUMAN,tr|Q6R954|Q6R954_HUMAN,tr|Q8WUT1|Q8WUT1_HUMAN,tr|F8WEE2|F8WEE2_HUMAN" 6 2036.1419 1.46 53406 20213 3 2036.141654 679.7212 Polymerase delta-interacting protein 3 OS=Homo sapiens OX=9606 GN=POLDIP3 PE=1 SV=2 11 3316.2 - 1.66E+06 - - - -0.1017 - 3.304 0.587 - 258.9 1 2 0 -0.0002 20 0 0 0 4.60E+07 3.15E+07 - - - 7.9838 0.9999 221125_WJC_METTL3_EV_vs_WT_F04.20214.20214.4 1.56E-10 20/96 R.K[136.11]FGEAIGMGFPVK[136.11]VPYR[166.11].K "sp|P78347|GTF2I_HUMAN,tr|A0A494C1K3|A0A494C1K3_HUMAN" 2 1921.0494 1.29 53407 20214 4 1921.046197 481.2696 General transcription factor II-I OS=Homo sapiens OX=9606 GN=GTF2I PE=1 SV=2 9.7 3316.3 - 1.42E+06 - - - -1.6835 - 3.079 0.572 - 378.1 1 2 1 -0.0032 17 0 0 0 1.97E+07 1.52E+07 - - - 4.5943 0.9992 221125_WJC_METTL3_EV_vs_WT_F04.20215.20215.2 0.00918 22-Jul K.YNILGTNTIMDK.M "sp|Q00839|HNRPU_HUMAN,tr|A0A1W2PQL0|A0A1W2PQL0_HUMAN,tr|A0A1W2PPL4|A0A1W2PPL4_HUMAN,tr|A0A1W2PQ74|A0A1W2PQ74_HUMAN,tr|Q5RI18|Q5RI18_HUMAN,tr|A0A1W2PP35|A0A1W2PP35_HUMAN,tr|A0A1W2PPS1|A0A1W2PPS1_HUMAN,tr|A0A1W2PRZ7|A0A1W2PRZ7_HUMAN,tr|A0A1W2PPH7|A0A1W2PPH7_HUMAN,tr|A0A1W2PQD4|A0A1W2PQD4_HUMAN,tr|A0A1W2PP34|A0A1W2PP34_HUMAN,tr|A0A1X7SBS1|A0A1X7SBS1_HUMAN" 12 1381.6912 0.34 53408 20215 2 1381.688052 691.8529 Heterogeneous nuclear ribonucleoprotein U OS=Homo sapiens OX=9606 GN=HNRNPU PE=1 SV=6 5.83 3316.4 - 781913 - - - -2.2436 - 1.842 0.4 - 114.9 1 2 0 -0.0031 12 0 0 0 1.23E+07 3.63E+07 - - - 3.6017 0.9191 221125_WJC_METTL3_EV_vs_WT_F04.20216.20216.2 0.64 30-Jun K.VGEEFEEQTVDGRPC[160.03]K.S sp|P29373|RABP2_HUMAN 1 1878.8418 15.74 53409 20216 2 1878.836035 940.4282 Cellular retinoic acid-binding protein 2 OS=Homo sapiens OX=9606 GN=CRABP2 PE=1 SV=2 4.25 3316.6 - 480244 - - - -3.0641 - 1.172 0.106 - 33.3 1 2 0 -0.0058 16 0 0 0 1.83E+07 1.16E+06 - - - 0.2123 1 221125_WJC_METTL3_EV_vs_WT_F04.20220.20220.3 2.09E-08 30/84 R.K[136.11]DLYANTVLSGGTTMYPGIADR[166.11].M "sp|P63261|ACTG_HUMAN,sp|P60709|ACTB_HUMAN,tr|A0A804GS07|A0A804GS07_HUMAN,tr|E7EVS6|E7EVS6_HUMAN,tr|A0A6Q8PFE4|A0A6Q8PFE4_HUMAN,tr|A0A2R8Y793|A0A2R8Y793_HUMAN,tr|I3L4N8|I3L4N8_HUMAN" 7 2360.1801 0.96 53411 20220 3 2360.176046 787.734 "Actin, cytoplasmic 2 OS=Homo sapiens OX=9606 GN=ACTG1 PE=1 SV=1" 5.96 3317.1 - 4.32E+06 - - - -1.7249 - 5.194 0.649 - 824 1 2 0 -0.0041 22 0 0 0 1.07E+08 1.11E+08 - - - 9.6805 1 221125_WJC_METTL3_EV_vs_WT_F04.20221.20221.3 1.04E-12 22/84 R.SNVASSAAC[160.03]SSASSLGLGLAYR.R sp|Q16352|AINX_HUMAN 1 2128.0219 0.64 53412 20221 3 2128.024606 710.3479 Alpha-internexin OS=Homo sapiens OX=9606 GN=INA PE=1 SV=2 7.94 3317.1 - 2.34E+06 - - - 1.2801 - 4.12 0.71 - 580.9 1 2 0 0.0027 22 0 0 0 4.46E+07 7.00E+07 - - - 9.8118 0.9999 221125_WJC_METTL3_EV_vs_WT_F04.20222.20222.3 2.10E-06 Dec-36 R.KDAEDWFFSK.T "sp|Q04695|K1C17_HUMAN,tr|K7ESE1|K7ESE1_HUMAN,tr|F5GWP8|F5GWP8_HUMAN" 3 1271.5823 201.11 53413 20222 3 1271.580437 424.868 "Keratin, type I cytoskeletal 17 OS=Homo sapiens OX=9606 GN=KRT17 PE=1 SV=2" 4.56 3317.2 - 1.78E+06 - - - -1.4281 - 2.111 0.481 - 248.8 1 2 0 -0.0018 10 0 0 0 6.30E+07 3.13E+05 - - - 6.0842 1 221125_WJC_METTL3_EV_vs_WT_F04.20224.20224.2 1.13E-07 16/26 K.QNLSELEQLNENLK[136.11].K "sp|Q15643|TRIPB_HUMAN,tr|H0YJ97|H0YJ97_HUMAN" 2 1678.8617 2 53415 20224 2 1679.862704 840.4381 Thyroid receptor-interacting protein 11 OS=Homo sapiens OX=9606 GN=TRIP11 PE=1 SV=3 4.25 3317.4 - 1.35E+06 - - - 596.2224 - 3.122 0.561 - 958.8 1 2 0 1.001 14 0 0 0 4.89E+07 2.44E+07 - - - 5.7272 1 221125_WJC_METTL3_EV_vs_WT_F04.20225.20225.2 2.51E-09 20/32 K.ELTTEIDNNIEQISSYK.S "sp|P13645|K1C10_HUMAN,tr|A0A1B0GVI3|A0A1B0GVI3_HUMAN" 2 1995.9637 999 53416 20225 2 1995.960835 998.9891 "Keratin, type I cytoskeletal 10 OS=Homo sapiens OX=9606 GN=KRT10 PE=1 SV=6" 4 3317.6 - 1.11E+06 - - - -1.4259 - 3.844 0.657 - 1227.9 1 2 0 -0.0028 17 0 0 0 1.58E+08 0.00E+00 - - - 7.2032 1 221125_WJC_METTL3_EV_vs_WT_F04.20226.20226.3 7.68E-07 24/68 K.TFFEELAVEDKQAGEEEK.V "sp|Q8NE71|ABCF1_HUMAN,tr|A0A0G2JIC2|A0A0G2JIC2_HUMAN,tr|Q5STZ8|Q5STZ8_HUMAN,tr|A0A0G2JJB9|A0A0G2JJB9_HUMAN" 4 2097.9742 1.78 53417 20226 3 2097.972555 700.332 ATP-binding cassette sub-family F member 1 OS=Homo sapiens OX=9606 GN=ABCF1 PE=1 SV=2 4.06 3317.7 - 801417 - - - -0.806 - 4.1 0.635 - 455.6 1 2 1 -0.0017 18 0 0 0 2.01E+07 1.13E+07 - - - 9.1327 1 221125_WJC_METTL3_EV_vs_WT_F04.20228.20228.2 2.97E-12 22/42 R.SNVASSAAC[160.03]SSASSLGLGLAYR.R sp|Q16352|AINX_HUMAN 1 2128.0219 2.85 53419 20228 2 2128.024967 1065.0182 Alpha-internexin OS=Homo sapiens OX=9606 GN=INA PE=1 SV=2 7.94 3318 - 498884 - - - 1.4497 - 4.501 0.713 - 1619.8 1 2 0 0.0031 22 0 0 0 5.76E+06 2.02E+06 - - - 8.0046 1 221125_WJC_METTL3_EV_vs_WT_F04.20231.20231.3 2.11E-09 18/68 R.HDIAFVEFDNEVQAGAAR[166.11].D "sp|P09012|SNRPA_HUMAN,tr|M0R268|M0R268_HUMAN" 2 1997.9471 1.55 53421 20231 3 1997.94597 666.9896 U1 small nuclear ribonucleoprotein A OS=Homo sapiens OX=9606 GN=SNRPA PE=1 SV=3 4.31 3318.2 - 2.42E+06 - - - -0.5526 - 3.586 0.591 - 503.7 1 2 0 -0.0011 18 0 0 0 2.71E+07 1.75E+07 - - - 8.3087 1 221125_WJC_METTL3_EV_vs_WT_F04.20232.20232.3 2.91E-08 13/60 R.VSLDVNHFAPDELTVK.T "sp|P04792|HSPB1_HUMAN,tr|A0A6Q8PGY2|A0A6Q8PGY2_HUMAN,tr|A0A6Q8PHJ6|A0A6Q8PHJ6_HUMAN,tr|A0A6Q8PHA6|A0A6Q8PHA6_HUMAN,tr|A0A6Q8PF43|A0A6Q8PF43_HUMAN,tr|A0A6Q8PFK8|A0A6Q8PFK8_HUMAN,tr|A0A6Q8PGK1|A0A6Q8PGK1_HUMAN,tr|A0A6Q8PH65|A0A6Q8PH65_HUMAN,tr|A0A6Q8PFE7|A0A6Q8PFE7_HUMAN" 9 1782.9152 2.56 53422 20232 3 1782.912779 595.3123 Heat shock protein beta-1 OS=Homo sapiens OX=9606 GN=HSPB1 PE=1 SV=2 4.54 3318.3 - 6.24E+06 - - - -1.3663 - 3.216 0.576 - 240.5 1 2 0 -0.0024 16 0 0 0 1.96E+08 7.65E+07 - - - 7.9584 1 221125_WJC_METTL3_EV_vs_WT_F04.20233.20233.3 4.12E-06 16/60 K.IEVIKPGDLGVDLTSK.L "sp|P38117|ETFB_HUMAN,tr|M0QY67|M0QY67_HUMAN" 2 1682.9455 1.03 53423 20233 3 1682.945876 561.9891 Electron transfer flavoprotein subunit beta OS=Homo sapiens OX=9606 GN=ETFB PE=1 SV=3 4.56 3318.3 - 4.64E+06 - - - 0.2519 - 3.264 0.534 - 236.3 1 2 0 0.0004 16 0 0 0 1.24E+08 1.21E+08 - - - 7.5288 1 221125_WJC_METTL3_EV_vs_WT_F04.20234.20234.3 1.19E-08 18/48 R.K[136.11]IEEIK[136.11]DFLLTAR[166.11].R "sp|P63173|RL38_HUMAN,tr|J3KT73|J3KT73_HUMAN,tr|J3QL01|J3QL01_HUMAN,tr|J3KSP2|J3KSP2_HUMAN" 4 1600.9399 1.06 53424 20234 3 1600.93835 534.6539 60S ribosomal protein L38 OS=Homo sapiens OX=9606 GN=RPL38 PE=1 SV=2 6.18 3318.4 - 3.55E+06 - - - -0.9451 - 2.968 0.606 - 445 1 2 1 -0.0015 13 0 0 0 3.83E+09 3.62E+09 - - - 8.2455 0.9999 221125_WJC_METTL3_EV_vs_WT_F04.20235.20235.3 1.32E-06 16/60 R.GNSLTLIDLPGHESLR.L sp|Q9Y5M8|SRPRB_HUMAN 1 1720.9108 1.08 53425 20235 3 1720.909599 574.6442 Signal recognition particle receptor subunit beta OS=Homo sapiens OX=9606 GN=SRPRB PE=1 SV=3 5.32 3318.4 - 2.98E+06 - - - -0.6967 - 3.044 0.316 - 290.4 1 2 0 -0.0012 16 0 0 0 4.42E+07 4.08E+07 - - - 4.919 1 221125_WJC_METTL3_EV_vs_WT_F04.20236.20236.3 1.45E-07 15/60 R.VSLDVNHFAPDELTVK[136.11].T "sp|P04792|HSPB1_HUMAN,tr|A0A6Q8PGY2|A0A6Q8PGY2_HUMAN,tr|A0A6Q8PHJ6|A0A6Q8PHJ6_HUMAN,tr|A0A6Q8PHA6|A0A6Q8PHA6_HUMAN,tr|A0A6Q8PF43|A0A6Q8PF43_HUMAN,tr|A0A6Q8PFK8|A0A6Q8PFK8_HUMAN,tr|A0A6Q8PGK1|A0A6Q8PGK1_HUMAN,tr|A0A6Q8PH65|A0A6Q8PH65_HUMAN,tr|A0A6Q8PFE7|A0A6Q8PFE7_HUMAN" 9 1790.9294 2.56 53426 20236 3 1790.926361 597.9837 Heat shock protein beta-1 OS=Homo sapiens OX=9606 GN=HSPB1 PE=1 SV=2 4.54 3318.5 - 2.89E+06 - - - -1.7053 - 3.025 0.546 - 248.1 1 2 0 -0.0031 16 0 0 0 1.96E+08 7.65E+07 - - - 7.4667 0.9999 221125_WJC_METTL3_EV_vs_WT_F04.20237.20237.3 3.67E-09 21/48 R.KIEEIKDFLLTAR.R "sp|P63173|RL38_HUMAN,tr|J3KT73|J3KT73_HUMAN,tr|J3QL01|J3QL01_HUMAN,tr|J3KSP2|J3KSP2_HUMAN" 4 1574.9032 1.06 53427 20237 3 1574.90266 525.975 60S ribosomal protein L38 OS=Homo sapiens OX=9606 GN=RPL38 PE=1 SV=2 6.18 3318.5 - 2.31E+06 - - - -0.3391 - 3.312 0.428 - 732.4 1 2 1 -0.0005 13 0 0 0 3.83E+09 3.62E+09 - - - 6.5585 1 221125_WJC_METTL3_EV_vs_WT_F04.20239.20239.3 6.10E-09 19/60 K.ANIVHLMLSSPEQIQK.Q sp|P55060|XPO2_HUMAN 1 1806.9662 0.89 53429 20239 3 1806.965462 603.3293 Exportin-2 OS=Homo sapiens OX=9606 GN=CSE1L PE=1 SV=3 6.79 3318.7 - 1.14E+06 - - - -0.4112 - 3.834 0.54 - 605.2 1 2 0 -0.0007 16 0 0 0 7.20E+07 8.13E+07 - - - 8.0085 0.9998 221125_WJC_METTL3_EV_vs_WT_F04.20243.20243.4 0.000221 17/72 R.KIEEIKDFLLTAR.R "sp|P63173|RL38_HUMAN,tr|J3KT73|J3KT73_HUMAN,tr|J3QL01|J3QL01_HUMAN,tr|J3KSP2|J3KSP2_HUMAN" 4 1574.9032 0.99 53431 20243 4 1574.902261 394.7331 60S ribosomal protein L38 OS=Homo sapiens OX=9606 GN=RPL38 PE=1 SV=2 6.18 3319.3 - 2.01E+06 - - - -0.5924 - 2.814 0.449 - 294.2 1 2 1 -0.0009 13 0 0 0 8.79E+08 8.91E+08 - - - 3.5174 0.9996 221125_WJC_METTL3_EV_vs_WT_F04.20246.20246.4 0.000192 16/72 R.K[136.11]IEEIK[136.11]DFLLTAR[166.11].R "sp|P63173|RL38_HUMAN,tr|J3KT73|J3KT73_HUMAN,tr|J3QL01|J3QL01_HUMAN,tr|J3KSP2|J3KSP2_HUMAN" 4 1600.9399 0.99 53434 20246 4 1600.936576 401.2422 60S ribosomal protein L38 OS=Homo sapiens OX=9606 GN=RPL38 PE=1 SV=2 6.18 3319.5 - 2.94E+06 - - - -2.0532 - 2.806 0.444 - 220.3 1 2 1 -0.0033 13 0 0 0 8.78E+08 8.90E+08 - - - 3.4722 1 221125_WJC_METTL3_EV_vs_WT_F04.20247.20247.2 0.00112 19/30 R.TVSSSSLPSLEEYEPR.G "sp|P42694|HELZ_HUMAN,tr|J3QS41|J3QS41_HUMAN" 2 1779.8527 2.14 53435 20247 2 1779.852308 890.9336 Probable helicase with zinc finger domain OS=Homo sapiens OX=9606 GN=HELZ PE=1 SV=2 4.25 3319.6 - 998342 - - - -0.2056 - 3.132 0.542 - 779.2 1 2 0 -0.0004 16 0 0 0 4.96E+07 2.32E+07 - - - 5.8509 1 221125_WJC_METTL3_EV_vs_WT_F04.20249.20249.4 2.66E-07 21/96 R.AVYHNMPLIWKPGYLDR.A "sp|Q92552|RT27_HUMAN,tr|G5EA06|G5EA06_HUMAN,tr|D6RH20|D6RH20_HUMAN" 3 2072.0666 1.01 53437 20249 4 2072.063256 519.0239 "28S ribosomal protein S27, mitochondrial OS=Homo sapiens OX=9606 GN=MRPS27 PE=1 SV=3" 8.55 3319.9 - 636678 - - - -1.6076 - 3.764 0.563 - 281.6 1 2 0 -0.0033 17 0 0 0 1.91E+07 1.88E+07 - - - 4.5856 1 221125_WJC_METTL3_EV_vs_WT_F04.20256.20256.2 2.74E-10 20/24 R.K[136.11]IEEIK[136.11]DFLLTAR[166.11].R "sp|P63173|RL38_HUMAN,tr|J3KT73|J3KT73_HUMAN,tr|J3QL01|J3QL01_HUMAN,tr|J3KSP2|J3KSP2_HUMAN" 4 1600.9399 1 53442 20256 2 1600.933051 801.4772 60S ribosomal protein L38 OS=Homo sapiens OX=9606 GN=RPL38 PE=1 SV=2 6.18 3320.8 - 1.34E+06 - - - -4.255 - 3.469 0.659 - 1225.7 1 2 1 -0.0068 13 0 0 0 2.32E+08 2.31E+08 - - - 7.0987 1 221125_WJC_METTL3_EV_vs_WT_F04.20261.20261.3 1.92E-05 18/48 K.TELDAHLENLLSK[136.11].A "sp|Q9Y371|SHLB1_HUMAN,tr|A0A087WW40|A0A087WW40_HUMAN" 2 1489.7868 1.35 53445 20261 3 1489.783911 497.6029 Endophilin-B1 OS=Homo sapiens OX=9606 GN=SH3GLB1 PE=1 SV=1 4.65 3321.5 - 1.80E+06 - - - -1.9211 - 3.252 0.464 - 462.2 1 2 0 -0.0029 13 0 0 0 5.47E+07 4.06E+07 - - - 6.9097 0.9998 221125_WJC_METTL3_EV_vs_WT_F04.20263.20263.3 0.0436 16/48 R.K[136.11]IEEIKDFLLTAR[166.11].R "sp|P63173|RL38_HUMAN,tr|J3KT73|J3KT73_HUMAN,tr|J3QL01|J3QL01_HUMAN,tr|J3KSP2|J3KSP2_HUMAN" 4 1592.9257 - 53447 20263 3 1592.925474 531.9825 60S ribosomal protein L38 OS=Homo sapiens OX=9606 GN=RPL38 PE=1 SV=2 6.18 3321.6 - 2.06E+06 - - - -0.1186 - 2.533 0.445 - 330.6 1 2 1 -0.0002 13 0 0 0 - - - - - 6.0211 1 221125_WJC_METTL3_EV_vs_WT_F04.20264.20264.3 6.73E-11 20/80 K.ADFDNTVAIHPTSSEELVTLR[166.11].- sp|P00390|GSHR_HUMAN 1 2324.1524 1.66 53448 20264 3 2324.149239 775.7247 "Glutathione reductase, mitochondrial OS=Homo sapiens OX=9606 GN=GSR PE=1 SV=2" 4.31 3321.8 - 1.43E+06 - - - -1.3493 - 4.042 0.586 - 239.9 1 2 0 -0.0031 21 0 0 0 4.18E+07 2.52E+07 - - - 8.4211 1 221125_WJC_METTL3_EV_vs_WT_F04.20277.20277.3 3.95E-05 17/48 K.R[166.11]LDQVEQELNELR[166.11].E sp|Q9UQE7|SMC3_HUMAN 1 1660.8647 0.62 53457 20277 3 1660.863708 554.6289 Structural maintenance of chromosomes protein 3 OS=Homo sapiens OX=9606 GN=SMC3 PE=1 SV=2 4.41 3323.3 - 1.18E+06 - - - -0.6202 - 3.465 0.457 - 579.5 1 2 0 -0.001 13 0 0 0 9.13E+06 1.47E+07 - - - 7.0042 1 221125_WJC_METTL3_EV_vs_WT_F04.20279.20279.3 1.51E-05 26/64 K.MLQAPESVLAEHYQDLR[166.11].R "sp|O00746|NDKM_HUMAN,tr|Q4TT34|Q4TT34_HUMAN,tr|H0Y6J0|H0Y6J0_HUMAN,tr|F2Z2X0|F2Z2X0_HUMAN,tr|A2IDC9|A2IDC9_HUMAN" 5 2008.9916 2.3 53459 20279 3 2008.98754 670.6711 "Nucleoside diphosphate kinase, mitochondrial OS=Homo sapiens OX=9606 GN=NME4 PE=1 SV=1" 4.65 3323.6 - 3.16E+06 - - - -2.0115 - 4.389 0.535 - 783.5 1 2 0 -0.004 17 0 0 0 1.60E+08 6.95E+07 - - - 8.2403 1 221125_WJC_METTL3_EV_vs_WT_F04.20281.20281.3 1.25E-11 20/68 K.LGELSDK[136.11]IGSTIDDTISK[136.11].F sp|Q14677|EPN4_HUMAN 1 1907.007 1.38 53461 20281 3 1907.004222 636.6763 Clathrin interactor 1 OS=Homo sapiens OX=9606 GN=CLINT1 PE=1 SV=1 4.23 3323.7 - 2.38E+06 - - - -1.4583 - 4.18 0.628 - 629.7 1 2 1 -0.0028 18 0 0 0 1.20E+08 8.70E+07 - - - 9.1024 1 221125_WJC_METTL3_EV_vs_WT_F04.20285.20285.2 4.79E-05 18/24 R.KIEEIKDFLLTAR.R "sp|P63173|RL38_HUMAN,tr|J3KT73|J3KT73_HUMAN,tr|J3QL01|J3QL01_HUMAN,tr|J3KSP2|J3KSP2_HUMAN" 4 1574.9032 1 53463 20285 2 1574.900352 788.4589 60S ribosomal protein L38 OS=Homo sapiens OX=9606 GN=RPL38 PE=1 SV=2 6.18 3324.3 - 8.99E+06 - - - -1.8046 - 3.57 0.637 - 1051.9 1 2 1 -0.0028 13 0 0 0 2.32E+08 2.31E+08 - - - 7.0111 1 221125_WJC_METTL3_EV_vs_WT_F04.20286.20286.3 4.90E-12 18/68 K.LGELSDKIGSTIDDTISK.F sp|Q14677|EPN4_HUMAN 1 1890.9786 1.38 53464 20286 3 1890.976403 631.3335 Clathrin interactor 1 OS=Homo sapiens OX=9606 GN=CLINT1 PE=1 SV=1 4.23 3324.3 - 4.13E+06 - - - -1.1634 - 3.955 0.588 - 488.8 1 2 1 -0.0022 18 0 0 0 1.20E+08 8.70E+07 - - - 8.5189 1 221125_WJC_METTL3_EV_vs_WT_F04.20290.20290.3 5.10E-05 17/48 K.RLDQVEQELNELR.E sp|Q9UQE7|SMC3_HUMAN 1 1640.8482 0.62 53468 20290 3 1640.843931 547.9567 Structural maintenance of chromosomes protein 3 OS=Homo sapiens OX=9606 GN=SMC3 PE=1 SV=2 4.41 3324.8 - 987199 - - - -2.6005 - 3.393 0.522 - 633.9 1 2 0 -0.0043 13 0 0 0 9.04E+06 1.46E+07 - - - 7.671 0.9999 221125_WJC_METTL3_EV_vs_WT_F04.20297.20297.3 1.18E-07 21/60 R.HFLDFQGSAIPQAMQK[136.11].L sp|Q8N4Q0|PTGR3_HUMAN 1 1824.9072 1.44 53473 20297 3 1824.902814 609.3097 Prostaglandin reductase 3 OS=Homo sapiens OX=9606 GN=ZADH2 PE=1 SV=1 6.74 3325.6 - 1.39E+06 - - - -2.4253 - 2.736 0.492 - 243.7 1 2 0 -0.0044 16 0 0 0 2.56E+07 1.78E+07 - - - 6.6066 0.9996 221125_WJC_METTL3_EV_vs_WT_F04.20298.20298.3 3.57E-11 22/100 R.GAYGGGYGGYDDYGGYNDGYGFGSDR.F sp|P55795|HNRH2_HUMAN 1 2659.016 1.54 53474 20298 3 2659.016106 887.3459 Heterogeneous nuclear ribonucleoprotein H2 OS=Homo sapiens OX=9606 GN=HNRNPH2 PE=1 SV=1 3.77 3325.8 - 1.26E+06 - - - 0.0384 - 3.022 0.259 - 388.1 1 2 0 0.0001 26 0 0 0 1.15E+07 7.51E+06 - - - 3.9719 1 221125_WJC_METTL3_EV_vs_WT_F04.20303.20303.3 3.97E-09 20/72 K.NEDIPNVAVYPHNGMIDLK.Y sp|P54709|AT1B3_HUMAN 1 2138.0466 1.56 53477 20303 3 2138.043889 713.6895 Sodium\potassium-transporting ATPase subunit beta-3 OS=Homo sapiens OX=9606 GN=ATP1B3 PE=1 SV=1 4.54 3326.3 - 3.37E+06 - - - -1.2867 - 3.64 0.601 - 451.6 1 2 0 -0.0028 19 0 0 0 3.67E+07 2.35E+07 - - - 8.4139 0.9864 221125_WJC_METTL3_EV_vs_WT_F04.20306.20306.2 0.451 12-Sep K.KIEEYKR[166.11].E "sp|P23760|PAX3_HUMAN,sp|Q96P16|RPR1A_HUMAN,sp|P23759|PAX7_HUMAN" 3 974.5425 - 53480 20306 2 974.544944 488.2785 Paired box protein Pax-3 OS=Homo sapiens OX=9606 GN=PAX3 PE=1 SV=2 8.5 3326.7 - 879318 - - - 2.5581 - 1.577 0.104 - 257.2 1 2 0 0.0025 7 0 0 0 - - - - - 1.2517 0.9381 221125_WJC_METTL3_EV_vs_WT_F04.20308.20308.3 0.229 Nov-48 R.K[136.11]IEEIKDFLLTAR.R "sp|P63173|RL38_HUMAN,tr|J3KT73|J3KT73_HUMAN,tr|J3QL01|J3QL01_HUMAN,tr|J3KSP2|J3KSP2_HUMAN" 4 1582.9174 - 53482 20308 3 1582.915011 528.6464 60S ribosomal protein L38 OS=Homo sapiens OX=9606 GN=RPL38 PE=1 SV=2 6.18 3327 - 600950 - - - -1.5048 - 1.675 0.163 - 98.7 1 2 1 -0.0024 13 0 0 0 - - - - - 1.7551 0.9999 221125_WJC_METTL3_EV_vs_WT_F04.20313.20313.3 1.81E-09 15/72 K.NEDIPNVAVYPHNGMIDLK[136.11].Y sp|P54709|AT1B3_HUMAN 1 2146.0608 1.56 53485 20313 3 2146.055102 716.3609 Sodium\potassium-transporting ATPase subunit beta-3 OS=Homo sapiens OX=9606 GN=ATP1B3 PE=1 SV=1 4.54 3327.6 - 2.40E+06 - - - -2.6737 - 3.273 0.524 - 175.6 1 2 0 -0.0057 19 0 0 0 3.67E+07 2.35E+07 - - - 7.2935 0.9999 221125_WJC_METTL3_EV_vs_WT_F04.20314.20314.3 0.000225 Oct-56 K.EAPC[160.03]VLIYIPDGHTK.E "sp|P07814|SYEP_HUMAN,tr|V9GYZ6|V9GYZ6_HUMAN" 2 1711.8603 1.06 53486 20314 3 1711.860557 571.6274 Bifunctional glutamate\proline--tRNA ligase OS=Homo sapiens OX=9606 GN=EPRS1 PE=1 SV=5 5.32 3327.6 - 3.35E+06 - - - 0.125 - 1.945 0.431 - 77.8 1 2 0 0.0002 15 0 0 0 5.31E+07 4.99E+07 - - - 5.0811 0.9899 221125_WJC_METTL3_EV_vs_WT_F04.20315.20315.3 1.61E-06 14/48 L.DGIHLLDPDVVAR[166.11].F sp|Q86U44|MTA70_HUMAN 1 1428.76 0 53487 20315 3 1428.758854 477.2606 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 4.41 3327.8 - 1.78E+06 - - - -0.8357 - 2.731 0.355 - 372.1 1 1 0 -0.0012 13 0 0 0 9.35E+04 4.48E+07 - - - 5.2215 0.9999 221125_WJC_METTL3_EV_vs_WT_F04.20316.20316.3 1.90E-05 17/56 K.TVINIQDQFHAIVQK.L "sp|Q9UPS8|ANR26_HUMAN,tr|A0A6Q8PFU2|A0A6Q8PFU2_HUMAN,tr|E7ESJ3|E7ESJ3_HUMAN" 3 1752.9523 2.24 53488 20316 3 1752.948948 585.3247 Ankyrin repeat domain-containing protein 26 OS=Homo sapiens OX=9606 GN=ANKRD26 PE=1 SV=4 6.41 3327.9 - 1.52E+06 - - - -1.8945 - 2.869 0.437 - 199.3 1 2 0 -0.0033 15 0 0 0 1.05E+07 4.69E+06 - - - 6.1614 1 221125_WJC_METTL3_EV_vs_WT_F04.20318.20318.3 2.19E-11 23/68 K.SEASLHPVLMSEAPWNTR.A "sp|O96019|ACL6A_HUMAN,tr|H7C5S0|H7C5S0_HUMAN" 2 2023.9786 1.25 53490 20318 3 2023.973191 675.6668 Actin-like protein 6A OS=Homo sapiens OX=9606 GN=ACTL6A PE=1 SV=1 5.38 3328.1 - 1.00E+06 - - - -2.6527 - 3.789 0.537 - 538.1 1 2 0 -0.0054 18 0 0 0 1.77E+07 1.42E+07 - - - 7.8426 1 221125_WJC_METTL3_EV_vs_WT_F04.20319.20319.2 7.56E-11 16/30 R.QLC[160.03]DNAGFDATNILNK[136.11].L sp|Q99832|TCPH_HUMAN 1 1800.8556 0.18 53491 20319 2 1800.856186 901.4351 T-complex protein 1 subunit eta OS=Homo sapiens OX=9606 GN=CCT7 PE=1 SV=2 4.21 3328.3 - 948950 - - - 0.3265 - 3.411 0.669 - 873.9 1 2 0 0.0006 16 0 0 0 3.20E+07 1.79E+08 - - - 6.9987 0.9999 221125_WJC_METTL3_EV_vs_WT_F04.20324.20324.3 0.0215 16/44 R.DISLDSELHDLR.L "sp|Q15643|TRIPB_HUMAN,tr|H0YJ97|H0YJ97_HUMAN" 2 1411.6943 1.18 53494 20324 3 1411.692972 471.5721 Thyroid receptor-interacting protein 11 OS=Homo sapiens OX=9606 GN=TRIP11 PE=1 SV=3 4.22 3328.9 - 2.87E+06 - - - -0.957 - 2.447 0.404 - 254.3 1 2 0 -0.0014 12 0 0 0 3.19E+07 2.71E+07 - - - 5.5243 0.9999 221125_WJC_METTL3_EV_vs_WT_F04.20325.20325.3 0.000997 Dec-56 K.EAPC[160.03]VLIYIPDGHTK[136.11].E "sp|P07814|SYEP_HUMAN,tr|V9GYZ6|V9GYZ6_HUMAN" 2 1719.8745 1.06 53495 20325 3 1719.872653 574.2988 Bifunctional glutamate\proline--tRNA ligase OS=Homo sapiens OX=9606 GN=EPRS1 PE=1 SV=5 5.32 3328.9 - 3.55E+06 - - - -1.0989 - 1.972 0.429 - 144.5 1 2 0 -0.0019 15 0 0 0 5.31E+07 4.99E+07 - - - 5.0943 1 221125_WJC_METTL3_EV_vs_WT_F04.20326.20326.3 2.85E-06 19/44 R.DISLDSELHDLR[166.11].L "sp|Q15643|TRIPB_HUMAN,tr|H0YJ97|H0YJ97_HUMAN" 2 1421.7026 1.17 53496 20326 3 1421.701457 474.9081 Thyroid receptor-interacting protein 11 OS=Homo sapiens OX=9606 GN=TRIP11 PE=1 SV=3 4.22 3329 - 2.08E+06 - - - -0.799 - 2.462 0.527 - 380.8 1 2 0 -0.0011 12 0 0 0 3.19E+07 2.72E+07 - - - 6.9126 0.9999 221125_WJC_METTL3_EV_vs_WT_F04.20327.20327.3 0.000649 19/56 K.SINDNIAIFTEVQKR.S sp|Q07065|CKAP4_HUMAN 1 1746.9264 1.11 53497 20327 3 1746.926211 583.3161 Cytoskeleton-associated protein 4 OS=Homo sapiens OX=9606 GN=CKAP4 PE=1 SV=2 5.79 3329.2 - 1.91E+06 - - - -0.1357 - 2.527 0.39 - 242.8 1 2 0 -0.0002 15 0 0 0 1.63E+07 1.46E+07 - - - 5.307 1 221125_WJC_METTL3_EV_vs_WT_F04.20329.20329.3 2.47E-10 22/56 K.ITSAYLQDIENAYKK.T "sp|O95299|NDUAA_HUMAN,tr|A0A7I2V4N8|A0A7I2V4N8_HUMAN,tr|A0A7I2V2N6|A0A7I2V2N6_HUMAN,tr|H7C1Y7|H7C1Y7_HUMAN,tr|A0A7I2V5B2|A0A7I2V5B2_HUMAN,tr|A0A7I2V419|A0A7I2V419_HUMAN,tr|A0A7I2V2W9|A0A7I2V2W9_HUMAN,tr|A0A7I2V2X3|A0A7I2V2X3_HUMAN,tr|A0A7I2YQU0|A0A7I2YQU0_HUMAN,tr|H7C2X4|H7C2X4_HUMAN,tr|A0A7I2V438|A0A7I2V438_HUMAN,tr|E7ESZ7|E7ESZ7_HUMAN,tr|A0A7I2V5L0|A0A7I2V5L0_HUMAN,tr|A0A087WXC5|A0A087WXC5_HUMAN,tr|A0A7I2V458|A0A7I2V458_HUMAN,tr|A0A7I2V594|A0A7I2V594_HUMAN,tr|A0A7I2V327|A0A7I2V327_HUMAN,tr|A0A7I2V5U7|A0A7I2V5U7_HUMAN" 18 1755.9043 1.47 53499 20329 3 1755.904026 586.3087 "NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 10, mitochondrial OS=Homo sapiens OX=9606 GN=NDUFA10 PE=1 SV=1" 6.07 3329.4 - 1.11E+06 - - - -0.1652 - 3.549 0.513 - 534.6 1 2 0 -0.0003 15 0 0 0 4.08E+07 2.78E+07 - - - 7.5646 0.9809 221125_WJC_METTL3_EV_vs_WT_F04.20331.20331.3 0.0334 13/60 K.ANIVHLMLSSPEQIQK[136.11].Q sp|P55060|XPO2_HUMAN 1 1814.9804 0.89 53501 20331 3 1814.986038 606.0007 Exportin-2 OS=Homo sapiens OX=9606 GN=CSE1L PE=1 SV=3 6.79 3329.7 - 723020 - - - 3.1036 - 1.817 0.198 - 144.3 1 2 0 0.0056 16 0 0 0 7.20E+07 8.13E+07 - - - 2.2782 1 221125_WJC_METTL3_EV_vs_WT_F04.20336.20336.3 7.12E-07 15/56 K.ITSAYLQDIENAYK[136.11]K[136.11].T "sp|O95299|NDUAA_HUMAN,tr|A0A7I2V4N8|A0A7I2V4N8_HUMAN,tr|A0A7I2V2N6|A0A7I2V2N6_HUMAN,tr|H7C1Y7|H7C1Y7_HUMAN,tr|A0A7I2V5B2|A0A7I2V5B2_HUMAN,tr|A0A7I2V419|A0A7I2V419_HUMAN,tr|A0A7I2V2W9|A0A7I2V2W9_HUMAN,tr|A0A7I2V2X3|A0A7I2V2X3_HUMAN,tr|A0A7I2YQU0|A0A7I2YQU0_HUMAN,tr|H7C2X4|H7C2X4_HUMAN,tr|A0A7I2V438|A0A7I2V438_HUMAN,tr|E7ESZ7|E7ESZ7_HUMAN,tr|A0A7I2V5L0|A0A7I2V5L0_HUMAN,tr|A0A087WXC5|A0A087WXC5_HUMAN,tr|A0A7I2V458|A0A7I2V458_HUMAN,tr|A0A7I2V594|A0A7I2V594_HUMAN,tr|A0A7I2V327|A0A7I2V327_HUMAN,tr|A0A7I2V5U7|A0A7I2V5U7_HUMAN" 18 1771.9327 1.47 53504 20336 3 1771.931891 591.6515 "NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 10, mitochondrial OS=Homo sapiens OX=9606 GN=NDUFA10 PE=1 SV=1" 6.07 3330.3 - 1.74E+06 - - - -0.4656 - 2.896 0.533 - 201.5 1 2 0 -0.0008 15 0 0 0 4.08E+07 2.78E+07 - - - 7.2568 1 221125_WJC_METTL3_EV_vs_WT_F04.20337.20337.3 5.71E-09 13/60 R.QLC[160.03]DNAGFDATNILNK[136.11].L sp|Q99832|TCPH_HUMAN 1 1800.8556 0.26 53505 20337 3 1800.853997 601.2925 T-complex protein 1 subunit eta OS=Homo sapiens OX=9606 GN=CCT7 PE=1 SV=2 4.21 3330.3 - 2.87E+06 - - - -0.889 - 2.521 0.629 - 255.1 1 2 0 -0.0016 16 0 0 0 2.35E+07 9.17E+07 - - - 7.9248 0.9999 221125_WJC_METTL3_EV_vs_WT_F04.20338.20338.3 6.63E-07 Nov-44 R.DVDFELIKVEGK.V "sp|P48643|TCPE_HUMAN,tr|E9PCA1|E9PCA1_HUMAN,tr|B7ZAR1|B7ZAR1_HUMAN,tr|E7ENZ3|E7ENZ3_HUMAN" 4 1390.7344 0.59 53506 20338 3 1390.733439 464.5854 T-complex protein 1 subunit epsilon OS=Homo sapiens OX=9606 GN=CCT5 PE=1 SV=1 4.32 3330.5 - 1.37E+06 - - - -0.6888 - 2.066 0.53 - 98.2 1 2 1 -0.001 12 0 0 0 1.37E+07 2.31E+07 - - - 6.46 1 221125_WJC_METTL3_EV_vs_WT_F04.20339.20339.3 9.25E-08 18/64 R.TLIVTHSNQALNQLFEK.L sp|O60306|AQR_HUMAN 1 1955.0476 1.17 53507 20339 3 1955.05006 652.6898 RNA helicase aquarius OS=Homo sapiens OX=9606 GN=AQR PE=1 SV=4 6.41 3330.6 - 990499 - - - 1.245 - 3.737 0.596 - 224.2 1 2 0 0.0024 17 0 0 0 1.54E+07 1.32E+07 - - - 8.5145 1 221125_WJC_METTL3_EV_vs_WT_F04.20340.20340.2 4.28E-11 16/34 K.QSSTPGSLFLSPPAPAPK.N "sp|Q9H4A3|WNK1_HUMAN,tr|F5GWT4|F5GWT4_HUMAN,tr|F6UYG0|F6UYG0_HUMAN" 3 1780.936 1.91 53508 20340 2 1780.939541 891.4753 Serine\threonine-protein kinase WNK1 OS=Homo sapiens OX=9606 GN=WNK1 PE=1 SV=2 8.75 3330.7 - 799616 - - - 2.0164 - 2.784 0.649 - 540 1 2 0 0.0036 18 0 0 0 1.91E+07 1.00E+07 - - - 6.3507 1 221125_WJC_METTL3_EV_vs_WT_F04.20346.20346.3 2.03E-07 17/76 K.QFYDQALQQAVVDDDANNAK.A "sp|P60033|CD81_HUMAN,tr|E9PJK1|E9PJK1_HUMAN,tr|E9PRJ8|E9PRJ8_HUMAN,tr|E9PIF1|E9PIF1_HUMAN,tr|E9PM31|E9PM31_HUMAN,tr|H0YDL9|H0YDL9_HUMAN,tr|H0YDJ9|H0YDJ9_HUMAN,tr|A6NMH8|A6NMH8_HUMAN,tr|H0YEE2|H0YEE2_HUMAN" 9 2252.0346 1.85 53512 20346 3 2252.037049 751.6855 CD81 antigen OS=Homo sapiens OX=9606 GN=CD81 PE=1 SV=1 3.77 3331.5 - 1.77E+06 - - - 1.1074 - 3.246 0.51 - 314.1 1 2 0 0.0025 20 0 0 0 1.62E+07 8.78E+06 - - - 7.0818 1 221125_WJC_METTL3_EV_vs_WT_F04.20347.20347.3 6.36E-11 19/72 R.SVVC[160.03]SDVEQQVIVIEEEKK.F "sp|Q7L014|DDX46_HUMAN,tr|A0A0C4DG89|A0A0C4DG89_HUMAN" 2 2217.1199 4.21 53513 20347 3 2217.125646 740.0472 Probable ATP-dependent RNA helicase DDX46 OS=Homo sapiens OX=9606 GN=DDX46 PE=1 SV=2 4.25 3331.7 - 1.14E+06 - - - 2.6074 - 3.179 0.649 - 282.4 1 2 0 0.0058 19 0 0 0 3.40E+07 8.08E+06 - - - 8.6156 1 221125_WJC_METTL3_EV_vs_WT_F04.20348.20348.3 5.69E-10 19/64 K.MLQAPESVLAEHYQDLR.R "sp|O00746|NDKM_HUMAN,tr|Q4TT34|Q4TT34_HUMAN,tr|H0Y6J0|H0Y6J0_HUMAN,tr|F2Z2X0|F2Z2X0_HUMAN,tr|A2IDC9|A2IDC9_HUMAN" 5 1998.9833 2.3 53514 20348 3 1998.984883 667.335 "Nucleoside diphosphate kinase, mitochondrial OS=Homo sapiens OX=9606 GN=NME4 PE=1 SV=1" 4.65 3331.7 - 3.12E+06 - - - 0.7864 - 3.957 0.623 - 446.7 1 2 0 0.0016 17 0 0 0 1.59E+08 6.93E+07 - - - 8.9603 1 221125_WJC_METTL3_EV_vs_WT_F04.20351.20351.3 2.53E-12 20/80 R.GAHGIIVVYDVTDQESFNNVK[136.11].Q "sp|P62820|RAB1A_HUMAN,tr|E7END7|E7END7_HUMAN" 2 2312.1528 0.94 53517 20351 3 2312.15015 771.7249 Ras-related protein Rab-1A OS=Homo sapiens OX=9606 GN=RAB1A PE=1 SV=3 4.54 3332 - 1.43E+06 - - - -1.1574 - 3.589 0.625 - 525.3 1 2 0 -0.0027 21 0 0 0 4.78E+07 5.08E+07 - - - 8.571 0.9999 221125_WJC_METTL3_EV_vs_WT_F04.20353.20353.3 7.03E-08 16/64 R.TLIVTHSNQALNQLFEK[136.11].L sp|O60306|AQR_HUMAN 1 1963.0618 1.17 53519 20353 3 1963.066567 655.3612 RNA helicase aquarius OS=Homo sapiens OX=9606 GN=AQR PE=1 SV=4 6.41 3332.2 - 1.24E+06 - - - 2.4151 - 2.406 0.526 - 167.7 1 2 0 0.0047 17 0 0 0 1.54E+07 1.32E+07 - - - 6.6211 1 221125_WJC_METTL3_EV_vs_WT_F04.20359.20359.3 5.00E-06 18/60 R.QLC[160.03]DNAGFDATNILNK.L sp|Q99832|TCPH_HUMAN 1 1792.8414 0.21 53523 20359 3 1792.840888 598.6211 T-complex protein 1 subunit eta OS=Homo sapiens OX=9606 GN=CCT7 PE=1 SV=2 4.21 3333 - 1.68E+06 - - - -0.2845 - 3.211 0.564 - 495.1 1 2 0 -0.0005 16 0 0 0 1.91E+07 9.14E+07 - - - 7.8212 1 221125_WJC_METTL3_EV_vs_WT_F04.20360.20360.2 1.82E-09 16/26 R.GVVDSEDIPLNLSR[166.11].E "sp|Q12931|TRAP1_HUMAN,sp|P08238|HS90B_HUMAN,sp|Q58FF7|H90B3_HUMAN,sp|P07900|HS90A_HUMAN,tr|I3L0K7|I3L0K7_HUMAN,tr|I3L239|I3L239_HUMAN" 6 1522.7867 0.9 53524 20360 2 1522.787956 762.4006 "Heat shock protein 75 kDa, mitochondrial OS=Homo sapiens OX=9606 GN=TRAP1 PE=1 SV=3" 4.03 3333.1 - 750310 - - - 0.853 - 3.146 0.578 - 805.2 1 2 0 0.0013 14 0 0 0 9.23E+06 1.03E+07 - - - 6.1859 1 221125_WJC_METTL3_EV_vs_WT_F04.20361.20361.2 9.33E-06 15/26 K.SQELNFVMDVNSSK[136.11].Y "sp|Q8IWZ3|ANKH1_HUMAN,tr|H0Y472|H0Y472_HUMAN,tr|H0Y7Y3|H0Y7Y3_HUMAN,tr|H0Y4P6|H0Y4P6_HUMAN,tr|H0Y785|H0Y785_HUMAN" 5 1604.7596 1.08 53525 20361 2 1604.759629 803.3871 Ankyrin repeat and KH domain-containing protein 1 OS=Homo sapiens OX=9606 GN=ANKHD1 PE=1 SV=1 4.37 3333.2 - 2.20E+06 - - - 0.0355 - 3.01 0.597 - 701.1 1 2 0 0.0001 14 0 0 0 3.31E+07 3.05E+07 - - - 6.2157 0.9958 221125_WJC_METTL3_EV_vs_WT_F04.20363.20363.3 0.033 Oct-36 K.DRPFFAGLVK.Y "sp|P15531|NDKA_HUMAN,tr|Q32Q12|Q32Q12_HUMAN,tr|J3KPD9|J3KPD9_HUMAN,tr|E5RHP0|E5RHP0_HUMAN,tr|E7ERL0|E7ERL0_HUMAN" 5 1148.6342 1.57 53527 20363 3 1148.633635 383.8854 Nucleoside diphosphate kinase A OS=Homo sapiens OX=9606 GN=NME1 PE=1 SV=1 8.75 3333.5 - 489292 - - - -0.5171 - 1.695 0.203 - 144.1 1 2 0 -0.0006 10 0 0 0 6.53E+06 4.16E+06 - - - 2.3441 0.9945 221125_WJC_METTL3_EV_vs_WT_F04.20364.20364.2 0.00292 24-Oct K.LLQDFFNGK[136.11]ELNK[136.11].S "sp|P54652|HSP72_HUMAN,sp|P11142|HSP7C_HUMAN,sp|P17066|HSP76_HUMAN,tr|E9PNE6|E9PNE6_HUMAN,tr|A8K7Q2|A8K7Q2_HUMAN,tr|E9PKE3|E9PKE3_HUMAN,tr|E9PN89|E9PN89_HUMAN" 7 1580.8533 0.001 53528 20364 2 1580.856768 791.4339 Heat shock-related 70 kDa protein 2 OS=Homo sapiens OX=9606 GN=HSPA2 PE=1 SV=1 6.07 3333.6 - 440754 - - - 2.1666 - 2.204 0.418 - 259.5 1 2 1 0.0034 13 0 0 0 0.00E+00 4.22E+06 - - - 4.1555 1 221125_WJC_METTL3_EV_vs_WT_F04.20365.20365.3 1.72E-08 16/68 R.AMTHVINQGMAMYWGTSR.W "sp|Q13303|KCAB2_HUMAN,sp|Q14722|KCAB1_HUMAN,tr|A0A087X1P8|A0A087X1P8_HUMAN,tr|A0A590UJJ4|A0A590UJJ4_HUMAN,tr|F8W6W4|F8W6W4_HUMAN,tr|Q5TG81|Q5TG81_HUMAN,tr|A0A5F9UN28|A0A5F9UN28_HUMAN,tr|A0A590UJB6|A0A590UJB6_HUMAN,tr|B7Z8E5|B7Z8E5_HUMAN,tr|A0A590UJ35|A0A590UJ35_HUMAN" 10 2052.9332 1.91 53529 20365 3 2052.936032 685.3183 Voltage-gated potassium channel subunit beta-2 OS=Homo sapiens OX=9606 GN=KCNAB2 PE=1 SV=2 8.8 3333.8 - 426218 - - - 1.3761 - 3.344 0.539 - 332.1 1 2 0 0.0028 18 0 0 0 1.35E+07 7.05E+06 - - - 7.5545 0.9996 221125_WJC_METTL3_EV_vs_WT_F04.20367.20367.2 0.00259 Jun-32 K.LSPPYSSPQEFAQDVGR[166.11].M "sp|Q13263|TIF1B_HUMAN,tr|M0R0K9|M0R0K9_HUMAN" 2 1886.9038 0.78 53531 20367 2 1886.901759 944.4592 Transcription intermediary factor 1-beta OS=Homo sapiens OX=9606 GN=TRIM28 PE=1 SV=5 4.37 3334 - 340374 - - - -1.088 - 1.417 0.474 - 41.9 1 2 0 -0.0021 17 0 0 0 1.57E+07 2.01E+07 - - - 3.3982 1 221125_WJC_METTL3_EV_vs_WT_F04.20372.20372.2 7.02E-07 15/26 K.SQELNFVMDVNSSK.Y "sp|Q8IWZ3|ANKH1_HUMAN,tr|H0Y472|H0Y472_HUMAN,tr|H0Y7Y3|H0Y7Y3_HUMAN,tr|H0Y4P6|H0Y4P6_HUMAN,tr|H0Y785|H0Y785_HUMAN" 5 1596.7454 1.08 53534 20372 2 1596.745665 799.38 Ankyrin repeat and KH domain-containing protein 1 OS=Homo sapiens OX=9606 GN=ANKHD1 PE=1 SV=1 4.37 3334.6 - 3.74E+06 - - - 0.1835 - 3.075 0.608 - 744.3 1 2 0 0.0003 14 0 0 0 3.31E+07 3.05E+07 - - - 6.3505 1 221125_WJC_METTL3_EV_vs_WT_F04.20374.20374.2 3.19E-07 14/24 K.DQGTYEDYVEGLR[166.11].V "sp|P60660|MYL6_HUMAN,tr|F8W1R7|F8W1R7_HUMAN,tr|G3V1V0|G3V1V0_HUMAN,tr|B7Z6Z4|B7Z6Z4_HUMAN,tr|F8VZU9|F8VZU9_HUMAN,tr|G8JLA2|G8JLA2_HUMAN,tr|H0YI43|H0YI43_HUMAN,tr|F8W180|F8W180_HUMAN,tr|G3V1Y7|G3V1Y7_HUMAN,tr|J3KND3|J3KND3_HUMAN,tr|F8VPF3|F8VPF3_HUMAN" 11 1553.6873 1.24 53536 20374 2 1553.687878 777.8509 Myosin light polypeptide 6 OS=Homo sapiens OX=9606 GN=MYL6 PE=1 SV=2 3.92 3334.8 - 1.77E+06 - - - 0.3482 - 2.921 0.576 - 1011.6 1 2 0 0.0005 13 0 0 0 2.57E+07 2.08E+07 - - - 6.0463 1 221125_WJC_METTL3_EV_vs_WT_F04.20375.20375.3 2.03E-11 18/72 R.ATENPEQVASEGLPEPVLR.K "sp|Q9BYD3|RM04_HUMAN,tr|X6RAY8|X6RAY8_HUMAN,tr|K7ES61|K7ES61_HUMAN,tr|K7ELF1|K7ELF1_HUMAN,tr|K7ELQ0|K7ELQ0_HUMAN,tr|K7EKI4|K7EKI4_HUMAN" 6 2035.0222 1.64 53537 20375 3 2035.026432 679.348 "39S ribosomal protein L4, mitochondrial OS=Homo sapiens OX=9606 GN=MRPL4 PE=1 SV=1" 4.09 3334.9 - 1.44E+06 - - - 2.0801 - 3.128 0.561 - 224.9 1 2 0 0.0042 19 0 0 0 1.90E+07 1.16E+07 - - - 7.5951 0.9999 221125_WJC_METTL3_EV_vs_WT_F04.20376.20376.3 0.00191 13/44 K.TSTVINWFHNYR[166.11].S "sp|P39880|CUX1_HUMAN,tr|A0A2R8Y852|A0A2R8Y852_HUMAN,tr|A0A2R8YDI1|A0A2R8YDI1_HUMAN" 3 1546.7556 1.2 53538 20376 3 1546.757907 516.5925 Homeobox protein cut-like 1 OS=Homo sapiens OX=9606 GN=CUX1 PE=1 SV=3 8.44 3335 - 957044 - - - 1.4715 - 2.766 0.405 - 365.8 1 2 0 0.0023 12 0 0 0 1.17E+07 9.74E+06 - - - 5.8748 1 221125_WJC_METTL3_EV_vs_WT_F04.20379.20379.3 0.00123 13/44 K.TSTVINWFHNYR.S "sp|P39880|CUX1_HUMAN,tr|A0A2R8Y852|A0A2R8Y852_HUMAN,tr|A0A2R8YDI1|A0A2R8YDI1_HUMAN" 3 1536.7474 1.2 53541 20379 3 1536.747455 513.2564 Homeobox protein cut-like 1 OS=Homo sapiens OX=9606 GN=CUX1 PE=1 SV=3 8.44 3335.3 - 887759 - - - 0.0612 - 2.782 0.416 - 375.4 1 2 0 0.0001 12 0 0 0 1.17E+07 9.74E+06 - - - 6.014 1 221125_WJC_METTL3_EV_vs_WT_F04.20381.20381.2 8.57E-10 15/38 F.GGGFGGGFGGDGGLLSGNEK.V "sp|P13645|K1C10_HUMAN,tr|A0A1B0GVI3|A0A1B0GVI3_HUMAN" 2 1738.7911 999 53543 20381 2 1738.791463 870.4028 "Keratin, type I cytoskeletal 10 OS=Homo sapiens OX=9606 GN=KRT10 PE=1 SV=6" 4.37 3335.5 - 613343 - - - 0.222 - 3.39 0.663 - 420.8 1 1 0 0.0004 20 0 0 0 1.07E+07 0.00E+00 - - - 6.9393 1 221125_WJC_METTL3_EV_vs_WT_F04.20383.20383.2 7.40E-09 14/36 R.ATENPEQVASEGLPEPVLR[166.11].K "sp|Q9BYD3|RM04_HUMAN,tr|X6RAY8|X6RAY8_HUMAN,tr|K7ES61|K7ES61_HUMAN,tr|K7ELF1|K7ELF1_HUMAN,tr|K7ELQ0|K7ELQ0_HUMAN,tr|K7EKI4|K7EKI4_HUMAN" 6 2045.0305 2.7 53545 20383 2 2046.02374 1023.5225 "39S ribosomal protein L4, mitochondrial OS=Homo sapiens OX=9606 GN=MRPL4 PE=1 SV=1" 4.09 3335.8 - 403948 - - - 485.6999 - 2.679 0.623 - 433.8 1 2 0 0.9933 19 0 0 0 7.68E+06 2.84E+06 - - - 5.7533 0.8434 221125_WJC_METTL3_EV_vs_WT_F04.20384.20384.2 0.00508 28-Sep K.SKELTTEIDNNIEQI.S "sp|P13645|K1C10_HUMAN,tr|A0A1B0GVI3|A0A1B0GVI3_HUMAN" 2 1745.8683 16.3 53546 20384 2 1745.869156 873.9414 "Keratin, type I cytoskeletal 10 OS=Homo sapiens OX=9606 GN=KRT10 PE=1 SV=6" 4 3335.9 - 311457 - - - 0.4766 - 1.888 0.429 - 128.2 1 1 1 0.0008 15 0 0 0 2.41E+06 1.48E+05 - - - 3.7718 0.9998 221125_WJC_METTL3_EV_vs_WT_F04.20388.20388.3 4.17E-06 14/60 R.EGLEDK[136.11]YNLQLNPEWR[166.11].M "sp|Q9NWS0|PIHD1_HUMAN,tr|M0QYF4|M0QYF4_HUMAN,tr|M0QXD5|M0QXD5_HUMAN,tr|M0R3A4|M0R3A4_HUMAN,tr|M0R2P8|M0R2P8_HUMAN,tr|M0QYA2|M0QYA2_HUMAN" 6 2020.9973 1.82 53549 20388 3 2021.000783 674.6731 PIH1 domain-containing protein 1 OS=Homo sapiens OX=9606 GN=PIH1D1 PE=1 SV=1 4.41 3336.3 - 4.39E+06 - - - 1.711 - 2.759 0.494 - 248.4 1 2 1 0.0035 16 0 0 0 7.92E+07 4.37E+07 - - - 6.6507 1 221125_WJC_METTL3_EV_vs_WT_F04.20389.20389.3 1.43E-08 13/64 K.HEPLVLFC[160.03]ESC[160.03]DTLTC[160.03]R.D "sp|Q13263|TIF1B_HUMAN,tr|M0R2I3|M0R2I3_HUMAN,tr|M0R3C0|M0R3C0_HUMAN" 3 2135.9438 0.84 53550 20389 3 2135.945974 712.9886 Transcription intermediary factor 1-beta OS=Homo sapiens OX=9606 GN=TRIM28 PE=1 SV=5 4.65 3336.4 - 1.88E+06 - - - 1.0028 - 2.979 0.595 - 289 1 2 0 0.0021 17 0 0 0 1.61E+07 1.91E+07 - - - 7.9307 1 221125_WJC_METTL3_EV_vs_WT_F04.20390.20390.3 1.82E-15 19/64 K.HEPLVLFC[160.03]ESC[160.03]DTLTC[160.03]R[166.11].D "sp|Q13263|TIF1B_HUMAN,tr|M0R2I3|M0R2I3_HUMAN,tr|M0R3C0|M0R3C0_HUMAN" 3 2145.9521 0.86 53551 20390 3 2145.95398 716.3246 Transcription intermediary factor 1-beta OS=Homo sapiens OX=9606 GN=TRIM28 PE=1 SV=5 4.65 3336.4 - 1.77E+06 - - - 0.8751 - 3.706 0.745 - 732.5 1 2 0 0.0019 17 0 0 0 1.58E+07 1.84E+07 - - - 10.1548 0.9996 221125_WJC_METTL3_EV_vs_WT_F04.20393.20393.3 0.00104 Nov-44 K.NKDWVFINYTYK.R sp|Q15208|STK38_HUMAN 1 1589.7878 0.96 53554 20393 3 1589.787609 530.9366 Serine\threonine-protein kinase 38 OS=Homo sapiens OX=9606 GN=STK38 PE=1 SV=1 8.43 3336.7 - 1.05E+06 - - - -0.1384 - 2.401 0.393 - 168.1 1 2 1 -0.0002 12 0 0 0 3.48E+07 3.61E+07 - - - 5.3493 0.9967 221125_WJC_METTL3_EV_vs_WT_F04.20399.20399.3 0.0112 Oct-44 R.DVDFELIK[136.11]VEGK[136.11].V "sp|P48643|TCPE_HUMAN,tr|E9PCA1|E9PCA1_HUMAN,tr|B7ZAR1|B7ZAR1_HUMAN,tr|E7ENZ3|E7ENZ3_HUMAN" 4 1406.7628 0.59 53560 20399 3 1406.764143 469.9282 T-complex protein 1 subunit epsilon OS=Homo sapiens OX=9606 GN=CCT5 PE=1 SV=1 4.32 3337.4 - 515363 - - - 0.9568 - 1.492 0.355 - 38 1 2 1 0.0013 12 0 0 0 1.37E+07 2.31E+07 - - - 3.6066 0.9999 221125_WJC_METTL3_EV_vs_WT_F04.20400.20400.2 6.19E-05 30-Dec R.SPQVPAAQQMLNFPEK.N sp|Q92922|SMRC1_HUMAN 1 1783.8927 23.2 53561 20400 2 1783.894042 892.9536 SWI\SNF complex subunit SMARCC1 OS=Homo sapiens OX=9606 GN=SMARCC1 PE=1 SV=3 5.72 3337.5 - 400152 - - - 0.7495 - 2.667 0.545 - 376.6 1 2 0 0.0013 16 0 0 0 2.58E+06 1.11E+05 - - - 5.4777 0.8576 221125_WJC_METTL3_EV_vs_WT_F04.20401.20401.2 0.701 Sep-32 R.ITNLTVNTGLDC[160.03]SEKTR[166.11].E sp|Q6UB98|ANR12_HUMAN 1 1930.9658 - 53562 20401 2 1930.966654 966.4902 Ankyrin repeat domain-containing protein 12 OS=Homo sapiens OX=9606 GN=ANKRD12 PE=1 SV=3 6.06 3337.7 - 372182 - - - 0.4625 - 1.22 0.12 - 125.5 1 2 1 0.0009 17 0 0 0 - - - - - 0.4159 1 221125_WJC_METTL3_EV_vs_WT_F04.20407.20407.3 1.02E-11 28/72 K.VLDSGAPIKIPVGPETLGR.L "sp|P06576|ATPB_HUMAN,tr|F8W079|F8W079_HUMAN,tr|H0YH81|H0YH81_HUMAN" 3 1918.0888 2.18 53567 20407 3 1918.091166 640.3702 "ATP synthase subunit beta, mitochondrial OS=Homo sapiens OX=9606 GN=ATP5F1B PE=1 SV=3" 6.04 3338.3 - 952984 - - - 1.2528 - 3.931 0.65 - 674.1 1 2 1 0.0024 19 0 0 0 2.10E+07 9.64E+06 - - - 9.1493 0.9999 221125_WJC_METTL3_EV_vs_WT_F04.20408.20408.3 6.29E-07 14/52 K.DVYDK[136.11]VDYLSSLGK[136.11].T "sp|Q14254|FLOT2_HUMAN,tr|E7EMK3|E7EMK3_HUMAN,tr|K7EKW9|K7EKW9_HUMAN,tr|J3QLD9|J3QLD9_HUMAN" 4 1616.8269 3.04 53568 20408 3 1616.828682 539.9496 Flotillin-2 OS=Homo sapiens OX=9606 GN=FLOT2 PE=1 SV=2 4.43 3338.4 - 795439 - - - 1.1306 - 2.844 0.582 - 175.3 1 2 1 0.0018 14 0 0 0 7.35E+06 2.42E+06 - - - 7.8059 1 221125_WJC_METTL3_EV_vs_WT_F04.20411.20411.2 1.55E-10 13/34 R.SLPSVETLGC[160.03]TSVIC[160.03]SDK.T "sp|P16615|AT2A2_HUMAN,sp|Q93084|AT2A3_HUMAN,sp|O14983|AT2A1_HUMAN,tr|H3BTW4|H3BTW4_HUMAN,tr|H7C5W9|H7C5W9_HUMAN" 5 1951.9231 1.33 53571 20411 2 1951.934246 976.9688 Sarcoplasmic\endoplasmic reticulum calcium ATPase 2 OS=Homo sapiens OX=9606 GN=ATP2A2 PE=1 SV=1 4.37 3338.8 - 423279 - - - 5.721 - 2.868 0.576 - 430 1 2 0 0.0112 18 0 0 0 3.72E+06 2.79E+06 - - - 5.8822 1 221125_WJC_METTL3_EV_vs_WT_F04.20413.20413.2 7.18E-10 19/36 R.ATENPEQVASEGLPEPVLR.K "sp|Q9BYD3|RM04_HUMAN,tr|X6RAY8|X6RAY8_HUMAN,tr|K7ES61|K7ES61_HUMAN,tr|K7ELF1|K7ELF1_HUMAN,tr|K7ELQ0|K7ELQ0_HUMAN,tr|K7EKI4|K7EKI4_HUMAN" 6 2035.0222 2.7 53573 20413 2 2035.02465 1018.5184 "39S ribosomal protein L4, mitochondrial OS=Homo sapiens OX=9606 GN=MRPL4 PE=1 SV=1" 4.09 3339 - 377317 - - - 1.2044 - 3.454 0.662 - 986.8 1 2 0 0.0025 19 0 0 0 7.68E+06 2.84E+06 - - - 6.9772 0.9997 221125_WJC_METTL3_EV_vs_WT_F04.20415.20415.2 0.00189 Nov-36 R.ILSAENIPNLPPGGGLAGK.R "sp|O75688|PPM1B_HUMAN,tr|B8ZZF0|B8ZZF0_HUMAN,tr|A0A3B3IS24|A0A3B3IS24_HUMAN,tr|C9JIR6|C9JIR6_HUMAN" 4 1817.0047 999 53575 20415 2 1817.005981 909.5096 Protein phosphatase 1B OS=Homo sapiens OX=9606 GN=PPM1B PE=1 SV=1 6 3339.3 - 317841 - - - 0.7056 - 1.862 0.41 - 195.9 1 2 0 0.0013 19 0 0 0 2.01E+06 0.00E+00 - - - 3.5972 1 221125_WJC_METTL3_EV_vs_WT_F04.20418.20418.2 5.22E-08 Nov-34 L.GSSTSSFQSMGSYGPFGR[166.11].M "sp|Q8ND56|LS14A_HUMAN,tr|A0A140TA76|A0A140TA76_HUMAN,tr|K7EMZ9|K7EMZ9_HUMAN" 3 1848.7976 0.92 53578 20418 2 1848.798763 925.4061 Protein LSM14 homolog A OS=Homo sapiens OX=9606 GN=LSM14A PE=1 SV=3 8.75 3339.7 - 163068 - - - 0.6117 - 2.339 0.691 - 286.1 1 1 0 0.0011 18 0 0 0 2.61E+06 2.84E+06 - - - 6.2335 1 221125_WJC_METTL3_EV_vs_WT_F04.20424.20424.3 2.28E-11 19/56 R.GQFSTDELVAEVEK[136.11]R[166.11].N "sp|Q00610|CLH1_HUMAN,sp|P53675|CLH2_HUMAN,tr|A0A087WVQ6|A0A087WVQ6_HUMAN,tr|A0A087WX41|A0A087WX41_HUMAN" 4 1724.87 0.88 53583 20424 3 1724.872601 575.9639 Clathrin heavy chain 1 OS=Homo sapiens OX=9606 GN=CLTC PE=1 SV=5 4.41 3340.3 - 2.42E+06 - - - 1.5085 - 3.468 0.695 - 577.4 1 2 0 0.0026 15 0 0 0 1.84E+07 2.09E+07 - - - 9.5328 1 221125_WJC_METTL3_EV_vs_WT_F04.20425.20425.3 1.98E-09 20/56 R.GQFSTDELVAEVEKR.N "sp|Q00610|CLH1_HUMAN,sp|P53675|CLH2_HUMAN,tr|A0A087WVQ6|A0A087WVQ6_HUMAN,tr|A0A087WX41|A0A087WX41_HUMAN" 4 1706.8475 0.88 53584 20425 3 1706.8497 569.9565 Clathrin heavy chain 1 OS=Homo sapiens OX=9606 GN=CLTC PE=1 SV=5 4.41 3340.4 - 2.02E+06 - - - 1.2719 - 3.632 0.602 - 623.6 1 2 0 0.0022 15 0 0 0 1.84E+07 2.09E+07 - - - 8.6166 0.9998 221125_WJC_METTL3_EV_vs_WT_F04.20426.20426.3 1.93E-05 15/72 K.EVIPVNVPEAQEEMKEVAK.H "sp|P07814|SYEP_HUMAN,tr|V9GYZ6|V9GYZ6_HUMAN" 2 2138.0929 0.95 53585 20426 3 2138.092824 713.7049 Bifunctional glutamate\proline--tRNA ligase OS=Homo sapiens OX=9606 GN=EPRS1 PE=1 SV=5 4.33 3340.4 - 1.39E+06 - - - -0.0454 - 2.372 0.471 - 190.6 1 2 1 -0.0001 19 0 0 0 1.07E+07 1.13E+07 - - - 5.9132 0.999 221125_WJC_METTL3_EV_vs_WT_F04.20428.20428.2 1.93E-05 13/22 K.NKDWVFINYTYK.R sp|Q15208|STK38_HUMAN 1 1589.7878 13.59 53587 20428 2 1589.787505 795.9012 Serine\threonine-protein kinase 38 OS=Homo sapiens OX=9606 GN=STK38 PE=1 SV=1 8.43 3340.6 - 899620 - - - -0.2038 - 2.601 0.535 - 354.8 1 2 1 -0.0003 12 0 0 0 4.86E+06 3.58E+05 - - - 5.5075 0.9977 221125_WJC_METTL3_EV_vs_WT_F04.20431.20431.3 0.556 Sep-44 K.QHTDTVVNFLIR.V "sp|Q9Y4A5|TRRAP_HUMAN,tr|H0Y4W2|H0Y4W2_HUMAN,tr|F2Z2U4|F2Z2U4_HUMAN" 3 1441.7678 1.07 53590 20431 3 1441.769151 481.5965 Transformation\transcription domain-associated protein OS=Homo sapiens OX=9606 GN=TRRAP PE=1 SV=3 6.74 3341 - 676854 - - - 0.9627 - 1.84 0.23 - 141.3 1 2 0 0.0014 12 0 0 0 1.32E+06 1.24E+06 - - - 2.7941 0.9994 221125_WJC_METTL3_EV_vs_WT_F04.20436.20436.3 0.157 Oct-44 K.QHTDTVVNFLIR[166.11].V "sp|Q9Y4A5|TRRAP_HUMAN,tr|H0Y4W2|H0Y4W2_HUMAN,tr|F2Z2U4|F2Z2U4_HUMAN" 3 1451.776 1.07 53595 20436 3 1451.776923 484.9326 Transformation\transcription domain-associated protein OS=Homo sapiens OX=9606 GN=TRRAP PE=1 SV=3 6.74 3341.7 - 440762 - - - 0.613 - 2.043 0.285 - 157.3 1 2 0 0.0009 12 0 0 0 1.32E+06 1.24E+06 - - - 3.6975 0.9999 221125_WJC_METTL3_EV_vs_WT_F04.20437.20437.2 2.03E-07 13/34 R.SLPSVETLGC[160.03]TSVIC[160.03]SDK[136.11].T "sp|P16615|AT2A2_HUMAN,sp|Q93084|AT2A3_HUMAN,sp|O14983|AT2A1_HUMAN,tr|H3BTW4|H3BTW4_HUMAN,tr|H7C5W9|H7C5W9_HUMAN" 5 1959.9373 1.33 53596 20437 2 1959.937179 980.9759 Sarcoplasmic\endoplasmic reticulum calcium ATPase 2 OS=Homo sapiens OX=9606 GN=ATP2A2 PE=1 SV=1 4.37 3341.8 - 414562 - - - -0.051 - 2.81 0.527 - 397.4 1 2 0 -0.0001 18 0 0 0 3.72E+06 2.79E+06 - - - 5.4735 1 221125_WJC_METTL3_EV_vs_WT_F04.20438.20438.2 5.47E-10 30-Dec R.EGLEDKYNLQLNPEWR.M "sp|Q9NWS0|PIHD1_HUMAN,tr|M0QYF4|M0QYF4_HUMAN,tr|M0QXD5|M0QXD5_HUMAN,tr|M0R3A4|M0R3A4_HUMAN,tr|M0R2P8|M0R2P8_HUMAN,tr|M0QYA2|M0QYA2_HUMAN" 6 2002.9749 4.47 53597 20438 2 2002.973053 1002.4947 PIH1 domain-containing protein 1 OS=Homo sapiens OX=9606 GN=PIH1D1 PE=1 SV=1 4.41 3341.9 - 335968 - - - -0.8997 - 2.563 0.655 - 393.7 1 2 1 -0.0018 16 0 0 0 1.42E+06 3.16E+05 - - - 6.1922 0.9998 221125_WJC_METTL3_EV_vs_WT_F04.20439.20439.3 0.00375 Oct-64 R.IATSLDGFDVASVQQQR.Q "sp|O60664|PLIN3_HUMAN,tr|K7ERZ3|K7ERZ3_HUMAN" 2 1833.9221 1.3 53598 20439 3 1833.922978 612.3146 Perilipin-3 OS=Homo sapiens OX=9606 GN=PLIN3 PE=1 SV=3 4.21 3342.1 - 254882 - - - 0.4837 - 1.975 0.371 - 119.5 1 2 0 0.0009 17 0 0 0 2.04E+06 1.57E+06 - - - 4.3954 0.8238 221125_WJC_METTL3_EV_vs_WT_F04.20443.20443.2 5.06 30-Jul R.QLC[160.03]DNAGFDATNILNK.L sp|Q99832|TCPH_HUMAN 1 1792.8414 0.18 53601 20443 2 1792.837195 897.428 T-complex protein 1 subunit eta OS=Homo sapiens OX=9606 GN=CCT7 PE=1 SV=2 4.21 3342.7 - 206528 - - - -2.3443 - 1.101 0.025 - 61 2 2 0 -0.0042 16 0 0 0 3.20E+07 1.79E+08 - - - -0.6736 1 221125_WJC_METTL3_EV_vs_WT_F04.20445.20445.3 4.99E-09 18/52 K.C[160.03]EFQDAYVLLSEK[136.11]K[136.11].L "sp|P10809|CH60_HUMAN,tr|A0A7I2V2X6|A0A7I2V2X6_HUMAN,tr|A0A7I2YQK6|A0A7I2YQK6_HUMAN,tr|A0A7I2V599|A0A7I2V599_HUMAN,tr|A0A7I2YQ71|A0A7I2YQ71_HUMAN,tr|A0A7I2V5M1|A0A7I2V5M1_HUMAN,tr|A0A7I2V5K3|A0A7I2V5K3_HUMAN,tr|A0A7I2V369|A0A7I2V369_HUMAN" 8 1744.8677 1.24 53603 20445 3 1744.870143 582.6298 "60 kDa heat shock protein, mitochondrial OS=Homo sapiens OX=9606 GN=HSPD1 PE=1 SV=2" 4.68 3342.8 - 2.85E+06 - - - 1.4156 - 3.307 0.713 - 385.4 1 2 0 0.0025 14 0 0 0 6.27E+07 5.04E+07 - - - 9.6671 0.9999 221125_WJC_METTL3_EV_vs_WT_F04.20448.20448.3 5.35E-05 14/48 R.LVNLQHLDLLNNK.L sp|Q96AG4|LRC59_HUMAN 1 1532.8675 1.49 53606 20448 3 1532.869722 511.9631 Leucine-rich repeat-containing protein 59 OS=Homo sapiens OX=9606 GN=LRRC59 PE=1 SV=1 6.74 3343 - 1.51E+06 - - - 1.4646 - 2.827 0.441 - 210.1 1 2 0 0.0022 13 0 0 0 6.56E+06 4.41E+06 - - - 6.2737 0.9999 221125_WJC_METTL3_EV_vs_WT_F04.20450.20450.3 4.14E-05 Dec-48 R.LVNLQHLDLLNNK[136.11].L sp|Q96AG4|LRC59_HUMAN 1 1540.8817 1.49 53608 20450 3 1540.882066 514.6345 Leucine-rich repeat-containing protein 59 OS=Homo sapiens OX=9606 GN=LRRC59 PE=1 SV=1 6.74 3343.2 - 1.13E+06 - - - 0.2525 - 2.484 0.429 - 145.6 1 2 0 0.0004 13 0 0 0 6.56E+06 4.41E+06 - - - 5.7897 1 221125_WJC_METTL3_EV_vs_WT_F04.20451.20451.3 1.02E-11 18/76 K.TDVLC[160.03]ADEEEDC[160.03]QAASLLQK[136.11].Y "sp|Q6W2J9|BCOR_HUMAN,tr|H7BZ37|H7BZ37_HUMAN,tr|H7C2V9|H7C2V9_HUMAN,tr|H7C231|H7C231_HUMAN" 4 2302.0184 3.14 53609 20451 3 2303.018285 768.3468 BCL-6 corepressor OS=Homo sapiens OX=9606 GN=BCOR PE=1 SV=1 3.71 3343.3 - 1.03E+06 - - - 434.3327 - 3.217 0.73 - 477.4 1 2 0 0.9998 20 0 0 0 1.56E+07 4.96E+06 - - - 9.2365 1 221125_WJC_METTL3_EV_vs_WT_F04.20452.20452.3 1.40E-10 16/84 K.SLSFSSDSEGNFETPEAETPIR.S "sp|O75410|TACC1_HUMAN,tr|E5RJG6|E5RJG6_HUMAN" 2 2399.0765 1.45 53610 20452 3 2399.081317 800.6994 Transforming acidic coiled-coil-containing protein 1 OS=Homo sapiens OX=9606 GN=TACC1 PE=1 SV=2 3.91 3343.5 - 755565 - - - 2.0166 - 2.749 0.679 - 214.1 1 2 0 0.0048 22 0 0 0 4.08E+06 2.81E+06 - - - 8.5063 0.9958 221125_WJC_METTL3_EV_vs_WT_F04.20454.20454.3 0.0226 Dec-88 K.TELAEPIAIR[166.11]PTSETVMYPAYAK[136.11].W sp|P07814|SYEP_HUMAN 1 2568.3264 0.97 53612 20454 3 2568.329999 857.1161 Bifunctional glutamate\proline--tRNA ligase OS=Homo sapiens OX=9606 GN=EPRS1 PE=1 SV=5 4.78 3343.7 - 676855 - - - 1.383 - 1.833 0.231 - 93.4 1 2 0 0.0036 23 0 0 0 2.39E+06 2.46E+06 - - - 2.536 0.9314 221125_WJC_METTL3_EV_vs_WT_F04.20457.20457.3 0.000254 Sep-88 R.AAVPSGASTGIYEALELRDGDKG.R "sp|P13929|ENOB_HUMAN,tr|E5RI09|E5RI09_HUMAN,tr|E5RG95|E5RG95_HUMAN,tr|E5RGZ4|E5RGZ4_HUMAN,tr|K7EPM1|K7EPM1_HUMAN,tr|K7EKN2|K7EKN2_HUMAN" 6 2276.1285 2.32 53615 20457 3 2276.125475 759.7168 Beta-enolase OS=Homo sapiens OX=9606 GN=ENO3 PE=1 SV=5 4.32 3344.1 - 472394 - - - -1.3092 - 2.782 0.388 - 28.2 5 1 1 -0.003 23 0 0 0 3.15E+06 1.36E+06 - - - 4.9418 1 221125_WJC_METTL3_EV_vs_WT_F04.20458.20458.3 9.04E-07 17/84 K.GLESLPPLRPQQNPVLPVAGER.N sp|P56192|SYMC_HUMAN 1 2366.307 1.12 53616 20458 3 2366.308807 789.7763 "Methionine--tRNA ligase, cytoplasmic OS=Homo sapiens OX=9606 GN=MARS1 PE=1 SV=2" 6.14 3344.3 - 457464 - - - 0.7514 - 2.587 0.531 - 142.8 1 2 0 0.0018 22 0 0 0 4.18E+07 3.73E+07 - - - 6.7131 1 221125_WJC_METTL3_EV_vs_WT_F04.20459.20459.2 4.79E-08 26-Nov K.YQGTILSIDDNLQR.T sp|Q02413|DSG1_HUMAN 1 1634.8264 -1 53617 20459 2 1634.831513 818.4205 Desmoglein-1 OS=Homo sapiens OX=9606 GN=DSG1 PE=1 SV=2 4.21 3344.4 - 434226 - - - 3.1275 - 2.625 0.626 - 356 1 2 0 0.0051 14 0 0 0 0.00E+00 0.00E+00 - - - 6.0849 1 221125_WJC_METTL3_EV_vs_WT_F04.20460.20460.3 1.57E-05 15/40 R.NC[160.03]WQNYLDFHR[166.11].C "sp|P14854|CX6B1_HUMAN,tr|A0A494C160|A0A494C160_HUMAN" 2 1561.676 1.55 53618 20460 3 1561.677893 521.5659 Cytochrome c oxidase subunit 6B1 OS=Homo sapiens OX=9606 GN=COX6B1 PE=1 SV=2 6.73 3344.5 - 407681 - - - 1.2115 - 2.737 0.501 - 379.1 1 2 0 0.0019 11 0 0 0 5.30E+06 3.41E+06 - - - 6.9855 0.9999 221125_WJC_METTL3_EV_vs_WT_F04.20461.20461.4 8.98E-06 17/96 R.LLGHWEEAAHDLALAC[160.03]K.L "sp|P50502|F10A1_HUMAN,sp|Q8IZP2|ST134_HUMAN,tr|H7C3I1|H7C3I1_HUMAN" 3 1932.9516 1.83 53619 20461 4 1932.954282 484.2452 Hsc70-interacting protein OS=Homo sapiens OX=9606 GN=ST13 PE=1 SV=2 5.27 3344.7 - 292481 - - - 1.3787 - 2.648 0.418 - 128.2 1 2 0 0.0027 17 0 0 0 9.72E+06 5.30E+06 - - - 3.2016 0.9999 221125_WJC_METTL3_EV_vs_WT_F04.20466.20466.3 1.43E-08 18/72 K.VLDSGAPIK[136.11]IPVGPETLGR[166.11].L "sp|P06576|ATPB_HUMAN,tr|F8W079|F8W079_HUMAN,tr|H0YH81|H0YH81_HUMAN" 3 1936.1112 2.18 53623 20466 3 1936.115849 646.3777 "ATP synthase subunit beta, mitochondrial OS=Homo sapiens OX=9606 GN=ATP5F1B PE=1 SV=3" 6.04 3345.1 - 1.39E+06 - - - 2.3842 - 2.885 0.614 - 202.7 1 2 1 0.0046 19 0 0 0 2.10E+07 9.64E+06 - - - 7.9873 0.9999 221125_WJC_METTL3_EV_vs_WT_F04.20467.20467.3 2.38E-05 Oct-40 R.NC[160.03]WQNYLDFHR.C "sp|P14854|CX6B1_HUMAN,tr|A0A494C160|A0A494C160_HUMAN" 2 1551.6677 1.37 53624 20467 3 1551.670543 518.2299 Cytochrome c oxidase subunit 6B1 OS=Homo sapiens OX=9606 GN=COX6B1 PE=1 SV=2 6.73 3345.2 - 1.05E+06 - - - 1.8122 - 1.927 0.525 - 154.2 1 2 0 0.0028 11 0 0 0 5.21E+06 3.79E+06 - - - 6.2559 0.9999 221125_WJC_METTL3_EV_vs_WT_F04.20468.20468.3 0.000183 18/84 K.GLESLPPLR[166.11]PQQNPVLPVAGER[166.11].N sp|P56192|SYMC_HUMAN 1 2386.3236 1.12 53625 20468 3 2386.326523 796.4485 "Methionine--tRNA ligase, cytoplasmic OS=Homo sapiens OX=9606 GN=MARS1 PE=1 SV=2" 6.14 3345.4 - 988591 - - - 1.2379 - 2.603 0.451 - 163.7 1 2 0 0.003 22 0 0 0 4.18E+07 3.73E+07 - - - 5.8355 1 221125_WJC_METTL3_EV_vs_WT_F04.20471.20471.2 1.88E-11 19/38 K.TDVLC[160.03]ADEEEDC[160.03]QAASLLQK.Y "sp|Q6W2J9|BCOR_HUMAN,tr|H7BZ37|H7BZ37_HUMAN,tr|H7C2V9|H7C2V9_HUMAN,tr|H7C231|H7C231_HUMAN" 4 2294.0042 2.1 53628 20471 2 2294.010818 1148.0094 BCL-6 corepressor OS=Homo sapiens OX=9606 GN=BCOR PE=1 SV=1 3.71 3345.7 - 612381 - - - 2.8662 - 4.071 0.796 - 972.6 1 2 0 0.0066 20 0 0 0 2.86E+06 1.36E+06 - - - 8.3697 1 221125_WJC_METTL3_EV_vs_WT_F04.20472.20472.3 1.61E-08 17/88 R.SAMSVQSSLVMHPIYAYGSEEQR.Q "sp|Q92947|GCDH_HUMAN,tr|K7EKT3|K7EKT3_HUMAN,tr|K7EKH1|K7EKH1_HUMAN" 3 2569.1941 0.45 53629 20472 3 2569.200535 857.4053 "Glutaryl-CoA dehydrogenase, mitochondrial OS=Homo sapiens OX=9606 GN=GCDH PE=1 SV=1" 5.38 3345.8 - 540666 - - - 2.5012 - 3.155 0.55 - 187.5 1 2 0 0.0064 23 0 0 0 3.20E+07 7.14E+07 - - - 7.3656 0.9994 221125_WJC_METTL3_EV_vs_WT_F04.20473.20473.3 5.72E-06 14/88 K.TELAEPIAIRPTSETVMYPAYAK.W sp|P07814|SYEP_HUMAN 1 2550.304 0.91 53630 20473 3 2550.317872 851.1086 Bifunctional glutamate\proline--tRNA ligase OS=Homo sapiens OX=9606 GN=EPRS1 PE=1 SV=5 4.78 3346 - 519810 - - - 5.4484 - 2.901 0.509 - 168.5 1 2 0 0.0139 23 0 0 0 2.39E+06 2.63E+06 - - - 6.7096 0.9996 221125_WJC_METTL3_EV_vs_WT_F04.20474.20474.4 3.04E-06 14/96 K.SLHTLFGDKLC[160.03]TVATLR.E "sp|P02768|ALBU_HUMAN,tr|A0A087WWT3|A0A087WWT3_HUMAN,tr|H7C013|H7C013_HUMAN,tr|A0A0C4DGB6|A0A0C4DGB6_HUMAN" 4 1931.0299 -1 53631 20474 4 1931.031938 483.7647 Albumin OS=Homo sapiens OX=9606 GN=ALB PE=1 SV=2 7.97 3346.1 - 504973 - - - 1.072 - 2.794 0.408 - 135.5 1 2 1 0.0021 17 0 0 0 0.00E+00 0.00E+00 - - - 3.1334 1 221125_WJC_METTL3_EV_vs_WT_F04.20476.20476.4 2.87E-08 13/96 R.LLGHWEEAAHDLALAC[160.03]K[136.11].L "sp|P50502|F10A1_HUMAN,sp|Q8IZP2|ST134_HUMAN,tr|H7C3I1|H7C3I1_HUMAN" 3 1940.9658 1.83 53633 20476 4 1940.967171 486.2487 Hsc70-interacting protein OS=Homo sapiens OX=9606 GN=ST13 PE=1 SV=2 5.27 3346.4 - 359430 - - - 0.6976 - 3.123 0.551 - 132.5 1 2 0 0.0014 17 0 0 0 9.72E+06 5.30E+06 - - - 4.4169 0.9968 221125_WJC_METTL3_EV_vs_WT_F04.20477.20477.3 0.000477 13/60 R.GRVNFDDYTVNLGGLK.D "sp|Q06210|GFPT1_HUMAN,tr|A0A6I8PRN4|A0A6I8PRN4_HUMAN,tr|A0A6I8PTT9|A0A6I8PTT9_HUMAN" 3 1766.8951 0.35 53634 20477 3 1766.900801 589.9723 Glutamine--fructose-6-phosphate aminotransferase [isomerizing] 1 OS=Homo sapiens OX=9606 GN=GFPT1 PE=1 SV=3 5.96 3346.5 - 349120 - - - 3.1994 - 2.138 0.384 - 139.2 1 2 1 0.0057 16 0 0 0 1.09E+06 3.13E+06 - - - 4.7694 0.9999 221125_WJC_METTL3_EV_vs_WT_F04.20478.20478.4 1.00E-06 13/78 R.VLPYPFTHHWQFER[166.11].T sp|Q9BVJ6|UT14A_HUMAN 1 1865.9241 1.88 53635 20478 4 1865.925224 467.4883 U3 small nucleolar RNA-associated protein 14 homolog A OS=Homo sapiens OX=9606 GN=UTP14A PE=1 SV=1 6.89 3346.6 - 231701 - - - 0.6056 - 2.655 0.436 - 149.5 1 2 0 0.0011 14 0 0 0 4.48E+06 2.39E+06 - - - 3.376 0.9997 221125_WJC_METTL3_EV_vs_WT_F04.20479.20479.2 0.000169 Nov-34 R.SEDTTGPITGLALTSVNK.F "sp|Q92538|GBF1_HUMAN,tr|A0A7I2V2L4|A0A7I2V2L4_HUMAN,tr|A0A7I2YQM2|A0A7I2YQM2_HUMAN,tr|A0A7I2V3Y5|A0A7I2V3Y5_HUMAN,tr|A0A7I2V342|A0A7I2V342_HUMAN,tr|A0A669KBG8|A0A669KBG8_HUMAN,tr|A0A7I2V2L5|A0A7I2V2L5_HUMAN,tr|A0A7I2V514|A0A7I2V514_HUMAN,tr|A0A7I2YQ65|A0A7I2YQ65_HUMAN,tr|A0A7I2V3Q4|A0A7I2V3Q4_HUMAN,tr|A0A669KB10|A0A669KB10_HUMAN,tr|A0A7I2V452|A0A7I2V452_HUMAN,tr|A0A7I2V4K2|A0A7I2V4K2_HUMAN,tr|A0A7I2YQA6|A0A7I2YQA6_HUMAN,tr|A0A7I2V529|A0A7I2V529_HUMAN,tr|A0A7P0RGV0|A0A7P0RGV0_HUMAN" 16 1802.9262 -1 53636 20479 2 1802.926577 902.4704 Golgi-specific brefeldin A-resistance guanine nucleotide exchange factor 1 OS=Homo sapiens OX=9606 GN=GBF1 PE=1 SV=2 4.37 3346.7 - 154190 - - - 0.2241 - 1.696 0.457 - 222.6 1 2 0 0.0004 18 0 0 0 0.00E+00 0.00E+00 - - - 3.7151 1 221125_WJC_METTL3_EV_vs_WT_F04.20484.20484.3 1.99E-22 30/80 K.DGNVLLHEMQIQHPTASLIAK[136.11].V sp|P40227|TCPZ_HUMAN 1 2322.2246 0.4 53639 20484 3 2322.228373 775.0821 T-complex protein 1 subunit zeta OS=Homo sapiens OX=9606 GN=CCT6A PE=1 SV=3 5.99 3347.4 - 5.17E+06 - - - 1.6458 - 5.149 0.767 - 1136.6 1 2 0 0.0038 21 0 0 0 6.69E+07 1.68E+08 - - - 11.0192 1 221125_WJC_METTL3_EV_vs_WT_F04.20486.20486.3 1.26E-09 19/52 K.FNADEFEDMVAEK[136.11]R[166.11].L "sp|P27635|RL10_HUMAN,tr|F8W7C6|F8W7C6_HUMAN,tr|X1WI28|X1WI28_HUMAN" 3 1717.7737 1.16 53641 20486 3 1717.777252 573.5985 60S ribosomal protein L10 OS=Homo sapiens OX=9606 GN=RPL10 PE=1 SV=4 4.18 3347.5 - 2.22E+06 - - - 2.0934 - 3.258 0.599 - 357.9 1 2 0 0.0036 14 0 0 0 1.03E+08 8.91E+07 - - - 8.3561 1 221125_WJC_METTL3_EV_vs_WT_F04.20488.20488.3 6.60E-18 32/80 K.DGNVLLHEMQIQHPTASLIAK.V sp|P40227|TCPZ_HUMAN 1 2314.2104 0.4 53643 20488 3 2314.212627 772.4107 T-complex protein 1 subunit zeta OS=Homo sapiens OX=9606 GN=CCT6A PE=1 SV=3 5.99 3347.8 - 1.55E+06 - - - 0.9835 - 5.317 0.718 - 1443.6 1 2 0 0.0023 21 0 0 0 6.69E+07 1.68E+08 - - - 10.5503 0.9973 221125_WJC_METTL3_EV_vs_WT_F04.20489.20489.3 0.00041 17/72 T.FDYQQAFGNSTGGFDGQAR.Q sp|Q96PK6|RBM14_HUMAN 1 2064.8926 3.15 53644 20489 3 2064.893518 689.3048 RNA-binding protein 14 OS=Homo sapiens OX=9606 GN=RBM14 PE=1 SV=2 4.21 3347.8 - 1.36E+06 - - - 0.4533 - 2.762 0.507 - 379.9 1 1 0 0.0009 19 0 0 0 2.05E+07 6.52E+06 - - - 6.6883 1 221125_WJC_METTL3_EV_vs_WT_F04.20490.20490.3 3.32E-07 13/60 K.EDSHPFDLGLYNEAVK.L "sp|P35244|RFA3_HUMAN,tr|B5MC59|B5MC59_HUMAN" 2 1832.8581 1.36 53645 20490 3 1832.858211 611.96 Replication protein A 14 kDa subunit OS=Homo sapiens OX=9606 GN=RPA3 PE=1 SV=1 4.31 3347.9 - 1.34E+06 - - - 0.0638 - 2.534 0.588 - 174.3 1 2 0 0.0001 16 0 0 0 2.29E+08 1.68E+08 - - - 7.4813 0.9999 221125_WJC_METTL3_EV_vs_WT_F04.20492.20492.3 1.58E-06 Oct-60 K.EDSHPFDLGLYNEAVK[136.11].L "sp|P35244|RFA3_HUMAN,tr|B5MC59|B5MC59_HUMAN" 2 1840.8723 1.36 53647 20492 3 1840.877221 614.6314 Replication protein A 14 kDa subunit OS=Homo sapiens OX=9606 GN=RPA3 PE=1 SV=1 4.31 3348 - 1.17E+06 - - - 2.6764 - 2.104 0.561 - 104.1 1 2 0 0.0049 16 0 0 0 2.29E+08 1.68E+08 - - - 6.7018 1 221125_WJC_METTL3_EV_vs_WT_F04.20493.20493.3 1.83E-12 26/88 R.SAMSVQSSLVMHPIYAYGSEEQR[166.11].Q "sp|Q92947|GCDH_HUMAN,tr|K7EKT3|K7EKT3_HUMAN,tr|K7EKH1|K7EKH1_HUMAN" 3 2579.2024 0.25 53648 20493 3 2579.204883 860.7414 "Glutaryl-CoA dehydrogenase, mitochondrial OS=Homo sapiens OX=9606 GN=GCDH PE=1 SV=1" 5.38 3348.2 - 1.10E+06 - - - 0.9708 - 4.624 0.616 - 517.8 1 2 0 0.0025 23 0 0 0 3.26E+07 1.31E+08 - - - 8.9993 1 221125_WJC_METTL3_EV_vs_WT_F04.20495.20495.2 2.17E-13 17/36 T.FDYQQAFGNSTGGFDGQAR.Q sp|Q96PK6|RBM14_HUMAN 1 2064.8926 2.52 53650 20495 2 2064.892692 1033.4536 RNA-binding protein 14 OS=Homo sapiens OX=9606 GN=RBM14 PE=1 SV=2 4.21 3348.4 - 622362 - - - 0.0533 - 3.628 0.752 - 845.1 1 1 0 0.0001 19 0 0 0 1.01E+07 4.02E+06 - - - 7.7635 1 221125_WJC_METTL3_EV_vs_WT_F04.20496.20496.4 2.81E-06 15/78 R.VLPYPFTHHWQFER.T sp|Q9BVJ6|UT14A_HUMAN 1 1855.9158 1.72 53651 20496 4 1855.91569 464.9862 U3 small nucleolar RNA-associated protein 14 homolog A OS=Homo sapiens OX=9606 GN=UTP14A PE=1 SV=1 6.89 3348.5 - 509553 - - - -0.0722 - 3.108 0.532 - 214.3 1 2 0 -0.0001 14 0 0 0 4.48E+06 2.61E+06 - - - 4.2692 0.9999 221125_WJC_METTL3_EV_vs_WT_F04.20500.20500.3 0.000223 Nov-44 K.NAAIAVLEELKK.L "sp|O95793|STAU1_HUMAN,tr|Q5JW30|Q5JW30_HUMAN,tr|Q5JW28|Q5JW28_HUMAN" 3 1297.7606 3.67 53655 20500 3 1297.761243 433.5941 Double-stranded RNA-binding protein Staufen homolog 1 OS=Homo sapiens OX=9606 GN=STAU1 PE=1 SV=2 6.14 3349.1 - 374805 - - - 0.5325 - 1.93 0.429 - 129.3 1 2 0 0.0007 12 0 0 0 1.79E+06 4.89E+05 - - - 5.1453 0.9982 221125_WJC_METTL3_EV_vs_WT_F04.20501.20501.3 0.038 Dec-52 R.QDLMNIAGTTLSSK[136.11].L "sp|P78371|TCPB_HUMAN,tr|F8VQ14|F8VQ14_HUMAN,tr|F5GWF6|F5GWF6_HUMAN" 3 1485.7588 0.31 53656 20501 3 1485.762927 496.2602 T-complex protein 1 subunit beta OS=Homo sapiens OX=9606 GN=CCT2 PE=1 SV=4 5.84 3349.2 - 352334 - - - 2.7481 - 2.204 0.279 - 172.7 1 2 0 0.0041 14 0 0 0 6.85E+05 2.20E+06 - - - 3.7496 0.9999 221125_WJC_METTL3_EV_vs_WT_F04.20502.20502.4 0.00112 15/84 R.IEIPIHIVPHVTIGK[136.11].V "sp|P46736|BRCC3_HUMAN,tr|X6RJS7|X6RJS7_HUMAN,tr|A0A0D9SF50|A0A0D9SF50_HUMAN,tr|A0A087WZR3|A0A087WZR3_HUMAN,tr|H9KVA9|H9KVA9_HUMAN" 5 1673.012 0.85 53657 20502 4 1673.014362 419.2603 Lys-63-specific deubiquitinase BRCC36 OS=Homo sapiens OX=9606 GN=BRCC3 PE=1 SV=2 6.92 3349.3 - 311293 - - - 1.4339 - 2.998 0.461 - 187.1 1 2 0 0.0024 15 0 0 0 1.86E+06 2.17E+06 - - - 3.6307 1 221125_WJC_METTL3_EV_vs_WT_F04.20503.20503.3 7.24E-11 21/56 K.DR[166.11]DPEAQFEMPYVVR[166.11].L "sp|O14744|ANM5_HUMAN,tr|H0YJD3|H0YJD3_HUMAN,tr|H7BZ44|H7BZ44_HUMAN" 3 1870.8787 2.95 53658 20503 3 1870.876317 624.6335 Protein arginine N-methyltransferase 5 OS=Homo sapiens OX=9606 GN=PRMT5 PE=1 SV=4 4.32 3349.5 - 307614 - - - -1.2593 - 3.423 0.674 - 632.3 1 2 1 -0.0024 15 0 0 0 3.24E+08 1.10E+08 - - - 9.2647 0.9998 221125_WJC_METTL3_EV_vs_WT_F04.20505.20505.3 2.66E-06 17/48 R.KIEEIKDFLLTAR.R "sp|P63173|RL38_HUMAN,tr|J3KT73|J3KT73_HUMAN,tr|J3QL01|J3QL01_HUMAN,tr|J3KSP2|J3KSP2_HUMAN" 4 1574.9032 -1 53659 20505 3 1574.906261 525.975 60S ribosomal protein L38 OS=Homo sapiens OX=9606 GN=RPL38 PE=1 SV=2 6.18 3349.7 - 737286 - - - 1.9474 - 2.891 0.52 - 383.8 1 2 1 0.0031 13 0 0 0 0.00E+00 0.00E+00 - - - 7.2149 0.9988 221125_WJC_METTL3_EV_vs_WT_F04.20506.20506.3 0.000339 Dec-48 R.K[136.11]IEEIK[136.11]DFLLTAR[166.11].R "sp|P63173|RL38_HUMAN,tr|J3KT73|J3KT73_HUMAN,tr|J3QL01|J3QL01_HUMAN,tr|J3KSP2|J3KSP2_HUMAN" 4 1600.9399 1.51 53660 20506 3 1600.941832 534.6539 60S ribosomal protein L38 OS=Homo sapiens OX=9606 GN=RPL38 PE=1 SV=2 6.18 3349.8 - 458298 - - - 1.2299 - 1.812 0.391 - 116.3 1 2 1 0.002 13 0 0 0 1.14E+07 7.56E+06 - - - 4.5104 1 221125_WJC_METTL3_EV_vs_WT_F04.20507.20507.3 1.44E-10 23/52 K.FNADEFEDMVAEKR.L "sp|P27635|RL10_HUMAN,tr|F8W7C6|F8W7C6_HUMAN,tr|X1WI28|X1WI28_HUMAN" 3 1699.7512 1.16 53661 20507 3 1699.754786 567.591 60S ribosomal protein L10 OS=Homo sapiens OX=9606 GN=RPL10 PE=1 SV=4 4.18 3349.9 - 5.33E+06 - - - 2.118 - 3.647 0.667 - 509 1 2 0 0.0036 14 0 0 0 1.03E+08 8.91E+07 - - - 9.414 0.999 221125_WJC_METTL3_EV_vs_WT_F04.20510.20510.3 5.01E-10 15/72 T.FDYQQAFGNSTGGFDGQAR[166.11].Q sp|Q96PK6|RBM14_HUMAN 1 2074.9009 3.15 53664 20510 3 2074.901179 692.6409 RNA-binding protein 14 OS=Homo sapiens OX=9606 GN=RBM14 PE=1 SV=2 4.21 3350.1 - 1.79E+06 - - - 0.1576 - 2.976 0.641 - 261.8 1 1 0 0.0003 19 0 0 0 2.05E+07 6.52E+06 - - - 8.3658 1 221125_WJC_METTL3_EV_vs_WT_F04.20511.20511.3 1.17E-12 23/92 R.SLYQSAGVAPESFEYIEAHGTGTK[136.11].V "sp|P49327|FAS_HUMAN,tr|A0A0U1RQF0|A0A0U1RQF0_HUMAN" 2 2549.2165 0.77 53665 20511 3 2549.215262 850.7461 Fatty acid synthase OS=Homo sapiens OX=9606 GN=FASN PE=1 SV=3 4.75 3350.2 - 1.27E+06 - - - -0.5045 - 3.894 0.63 - 749.7 1 2 0 -0.0013 24 0 0 0 4.11E+07 5.34E+07 - - - 8.7209 1 221125_WJC_METTL3_EV_vs_WT_F04.20513.20513.3 9.45E-08 21/92 R.SLYQSAGVAPESFEYIEAHGTGTK.V "sp|P49327|FAS_HUMAN,tr|A0A0U1RQF0|A0A0U1RQF0_HUMAN" 2 2541.2023 0.77 53667 20513 3 2541.205647 848.0747 Fatty acid synthase OS=Homo sapiens OX=9606 GN=FASN PE=1 SV=3 4.75 3350.4 - 1.08E+06 - - - 1.2982 - 3.901 0.628 - 536.4 1 2 0 0.0033 24 0 0 0 4.11E+07 5.34E+07 - - - 8.7023 0.9994 221125_WJC_METTL3_EV_vs_WT_F04.20514.20514.3 0.015 14/48 K.LLQDFFNGR[166.11]DLNK[136.11].S "sp|P0DMV8|HS71A_HUMAN,sp|P0DMV9|HS71B_HUMAN,tr|V9GZ37|V9GZ37_HUMAN,tr|A0A0G2JIW1|A0A0G2JIW1_HUMAN" 4 1596.8379 0.69 53668 20514 3 1596.838689 533.2866 Heat shock 70 kDa protein 1A OS=Homo sapiens OX=9606 GN=HSPA1A PE=1 SV=1 5.96 3350.6 - 953748 - - - 0.4872 - 2.502 0.345 - 175.4 1 2 1 0.0008 13 0 0 0 1.10E+07 1.58E+07 - - - 4.8727 1 221125_WJC_METTL3_EV_vs_WT_F04.20517.20517.3 1.25E-05 13/56 K.IC[160.03]DQWDALGSLTHSR[166.11].R "sp|O43707|ACTN4_HUMAN,tr|F5GXS2|F5GXS2_HUMAN,tr|H7C144|H7C144_HUMAN" 3 1767.8238 2.01 53671 20517 3 1767.823795 590.2819 Alpha-actinin-4 OS=Homo sapiens OX=9606 GN=ACTN4 PE=1 SV=2 5.21 3350.9 - 577492 - - - 0.004 - 2.875 0.562 - 186 1 2 0 0 15 0 0 0 5.72E+06 2.84E+06 - - - 7.5614 1 221125_WJC_METTL3_EV_vs_WT_F04.20518.20518.2 9.57E-12 15/36 T.FDYQQAFGNSTGGFDGQAR[166.11].Q sp|Q96PK6|RBM14_HUMAN 1 2074.9009 2.52 53672 20518 2 2074.902737 1038.4577 RNA-binding protein 14 OS=Homo sapiens OX=9606 GN=RBM14 PE=1 SV=2 4.21 3351.1 - 535796 - - - 0.9085 - 3.265 0.748 - 591.8 1 1 0 0.0019 19 0 0 0 1.01E+07 4.02E+06 - - - 7.4742 1 221125_WJC_METTL3_EV_vs_WT_F04.20521.20521.4 0.000106 13/84 R.IEIPIHIVPHVTIGK.V "sp|P46736|BRCC3_HUMAN,tr|X6RJS7|X6RJS7_HUMAN,tr|A0A0D9SF50|A0A0D9SF50_HUMAN,tr|A0A087WZR3|A0A087WZR3_HUMAN,tr|H9KVA9|H9KVA9_HUMAN" 5 1664.9978 0.88 53675 20521 4 1665.000472 417.2567 Lys-63-specific deubiquitinase BRCC36 OS=Homo sapiens OX=9606 GN=BRCC3 PE=1 SV=2 6.92 3351.4 - 333883 - - - 1.627 - 2.487 0.498 - 120.7 1 2 0 0.0027 15 0 0 0 1.02E+06 1.15E+06 - - - 3.8858 1 221125_WJC_METTL3_EV_vs_WT_F04.20523.20523.3 1.16E-06 14/84 K.ELPDPSQRPLGEPSAGLGEYLK.G "sp|Q9HC52|CBX8_HUMAN,tr|C9J6K3|C9J6K3_HUMAN" 2 2352.1961 14.4 53677 20523 3 2352.19511 785.0727 Chromobox protein homolog 8 OS=Homo sapiens OX=9606 GN=CBX8 PE=1 SV=3 4.41 3351.7 - 286982 - - - -0.4383 - 2.514 0.484 - 141.7 1 2 0 -0.001 22 0 0 0 6.96E+06 4.84E+05 - - - 6.1214 1 221125_WJC_METTL3_EV_vs_WT_F04.20524.20524.3 5.58E-07 15/116 R.C[160.03]LQLGSPGPGPVAAGPGPASVSGLAAGSGR.D sp|Q8IYS2|K2013_HUMAN 1 2644.3391 -1 53678 20524 3 2644.339568 882.4537 Uncharacterized protein KIAA2013 OS=Homo sapiens OX=9606 GN=KIAA2013 PE=1 SV=1 8.25 3351.8 - 218241 - - - 0.1641 - 3.285 0.541 - 116.8 1 2 0 0.0004 30 0 0 0 0.00E+00 0.00E+00 - - - 7.3078 0.9153 221125_WJC_METTL3_EV_vs_WT_F04.20528.20528.3 4.00E-06 15/76 L.AISTPDAPATQDGVESLLQK[136.11].F "sp|Q86U44|MTA70_HUMAN,tr|B4E349|B4E349_HUMAN,tr|F5H6D8|F5H6D8_HUMAN,tr|H0YFV6|H0YFV6_HUMAN,tr|B4DTN4|B4DTN4_HUMAN" 5 2048.0517 0.06 53680 20528 3 2049.053954 683.6912 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 4.03 3352.4 - 1.37E+06 - - - 489.3622 - 2.765 0.501 - 202.9 1 1 0 1.0022 20 0 0 0 8.89E+05 1.61E+07 - - - 6.3154 0.9998 221125_WJC_METTL3_EV_vs_WT_F04.20531.20531.2 6.81E-06 30-Oct K.SYELPDGQVITIGNER[166.11].F "sp|Q6S8J3|POTEE_HUMAN,sp|P63261|ACTG_HUMAN,sp|P68133|ACTS_HUMAN,sp|P62736|ACTA_HUMAN,sp|Q9BYX7|ACTBM_HUMAN,sp|P68032|ACTC_HUMAN,sp|Q562R1|ACTBL_HUMAN,sp|P60709|ACTB_HUMAN,sp|P63267|ACTH_HUMAN,sp|A5A3E0|POTEF_HUMAN,tr|A0A804GS07|A0A804GS07_HUMAN,tr|E7EVS6|E7EVS6_HUMAN,tr|A0A6Q8PFE4|A0A6Q8PFE4_HUMAN,tr|A0A2R8YEA7|A0A2R8YEA7_HUMAN,tr|A0A804HKV3|A0A804HKV3_HUMAN,tr|A0A2R8Y793|A0A2R8Y793_HUMAN,tr|I3L4N8|I3L4N8_HUMAN,tr|A6NL76|A6NL76_HUMAN" 18 1799.8929 3.13 53683 20531 2 1799.889738 900.9537 POTE ankyrin domain family member E OS=Homo sapiens OX=9606 GN=POTEE PE=2 SV=3 4.14 3352.8 - 341129 - - - -1.764 - 2.16 0.612 - 283.4 1 2 0 -0.0032 16 0 0 0 8.45E+06 2.70E+06 - - - 5.4536 1 221125_WJC_METTL3_EV_vs_WT_F04.20535.20535.3 2.67E-08 22/92 R.ELSLTPITGAK[136.11]PSATGYLGSVAAK[136.11].R "sp|O95785|WIZ_HUMAN,tr|A0A669KBG4|A0A669KBG4_HUMAN,tr|A0A2R8YFV2|A0A2R8YFV2_HUMAN,tr|A0A669KAV7|A0A669KAV7_HUMAN,tr|M0QXA7|M0QXA7_HUMAN,tr|A0A669KBH9|A0A669KBH9_HUMAN,tr|B9EGQ5|B9EGQ5_HUMAN" 7 2347.297 1.47 53685 20535 3 2347.294155 783.4396 Protein Wiz OS=Homo sapiens OX=9606 GN=WIZ PE=1 SV=2 8.59 3353.3 - 1.05E+06 - - - -1.2027 - 3.758 0.603 - 339.5 1 2 0 -0.0028 24 0 0 0 3.98E+07 2.70E+07 - - - 8.3369 1 221125_WJC_METTL3_EV_vs_WT_F04.20536.20536.2 7.67E-11 14/30 K.EDSHPFDLGLYNEAVK[136.11].L "sp|P35244|RFA3_HUMAN,tr|B5MC59|B5MC59_HUMAN" 2 1840.8723 1.42 53686 20536 2 1840.872569 921.4434 Replication protein A 14 kDa subunit OS=Homo sapiens OX=9606 GN=RPA3 PE=1 SV=1 4.31 3353.4 - 447351 - - - 0.1494 - 2.815 0.719 - 392.4 1 2 0 0.0003 16 0 0 0 9.23E+06 6.49E+06 - - - 6.8959 0.9981 221125_WJC_METTL3_EV_vs_WT_F04.20537.20537.3 0.018 13/64 R.EEEVTGPVIAPLFPQKR.E sp|O75643|U520_HUMAN 1 1909.0309 3.28 53687 20537 3 1909.040265 637.3509 U5 small nuclear ribonucleoprotein 200 kDa helicase OS=Homo sapiens OX=9606 GN=SNRNP200 PE=1 SV=2 4.79 3353.5 - 951214 - - - 4.8988 - 2.53 0.367 - 182.2 1 2 0 0.0094 17 0 0 0 1.80E+07 5.47E+06 - - - 4.9741 1 221125_WJC_METTL3_EV_vs_WT_F04.20538.20538.2 7.19E-10 30-Dec K.EDSHPFDLGLYNEAVK.L "sp|P35244|RFA3_HUMAN,tr|B5MC59|B5MC59_HUMAN" 2 1832.8581 1.42 53688 20538 2 1832.861964 917.4363 Replication protein A 14 kDa subunit OS=Homo sapiens OX=9606 GN=RPA3 PE=1 SV=1 4.31 3353.6 - 650940 - - - 2.1115 - 3.049 0.68 - 353.7 1 2 0 0.0039 16 0 0 0 9.23E+06 6.49E+06 - - - 6.8031 1 221125_WJC_METTL3_EV_vs_WT_F04.20553.20553.3 1.22E-07 23/92 R.ELSLTPITGAKPSATGYLGSVAAK.R "sp|O95785|WIZ_HUMAN,tr|A0A669KBG4|A0A669KBG4_HUMAN,tr|A0A2R8YFV2|A0A2R8YFV2_HUMAN,tr|A0A669KAV7|A0A669KAV7_HUMAN,tr|M0QXA7|M0QXA7_HUMAN,tr|A0A669KBH9|A0A669KBH9_HUMAN,tr|B9EGQ5|B9EGQ5_HUMAN" 7 2331.2686 1.48 53697 20553 3 2331.264438 778.0968 Protein Wiz OS=Homo sapiens OX=9606 GN=WIZ PE=1 SV=2 8.59 3355.5 - 2.33E+06 - - - -1.7759 - 3.707 0.558 - 527.6 1 2 0 -0.0041 24 0 0 0 3.99E+07 2.70E+07 - - - 7.8031 1 221125_WJC_METTL3_EV_vs_WT_F04.20558.20558.3 1.44E-08 19/88 K.LALPGHAESYNPPPEYLLSEEER[166.11].L sp|Q14137|BOP1_HUMAN 1 2620.2685 0.93 53702 20558 3 2620.264254 874.4301 Ribosome biogenesis protein BOP1 OS=Homo sapiens OX=9606 GN=BOP1 PE=1 SV=2 4.32 3356.1 - 484806 - - - -1.6082 - 3.697 0.589 - 423.5 1 2 0 -0.0042 23 0 0 0 1.83E+07 1.96E+07 - - - 8.173 1 221125_WJC_METTL3_EV_vs_WT_F04.20568.20568.3 2.12E-06 13/52 K.LTLDTIFVPNTGKK.S "sp|Q9Y277|VDAC3_HUMAN,tr|E5RJN6|E5RJN6_HUMAN,tr|E5RK27|E5RK27_HUMAN,tr|E5RFP6|E5RFP6_HUMAN,tr|E5RHZ6|E5RHZ6_HUMAN" 5 1545.8766 1.22 53710 20568 3 1545.878084 516.2995 Voltage-dependent anion-selective channel protein 3 OS=Homo sapiens OX=9606 GN=VDAC3 PE=1 SV=1 8.59 3357.3 - 592353 - - - 0.9315 - 2.655 0.531 - 184.3 1 2 0 0.0014 14 0 0 0 8.13E+07 6.64E+07 - - - 7.0547 1 221125_WJC_METTL3_EV_vs_WT_F04.20577.20577.2 1.13E-10 19/32 K.IETSINLAWTAGSNNTR.F sp|Q9Y277|VDAC3_HUMAN 1 1846.9173 1.14 53717 20577 2 1846.918563 924.4659 Voltage-dependent anion-selective channel protein 3 OS=Homo sapiens OX=9606 GN=VDAC3 PE=1 SV=1 6 3358.4 - 794005 - - - 0.6622 - 3.66 0.641 - 1225.8 1 2 0 0.0012 17 0 0 0 1.61E+07 1.41E+07 - - - 6.9649 1 221125_WJC_METTL3_EV_vs_WT_F04.20579.20579.4 7.74E-09 17/90 R.SAATLITHPFHVITLR[166.11].S "sp|Q9Y6C9|MTCH2_HUMAN,tr|E9PIE4|E9PIE4_HUMAN" 2 1786.0129 0.72 53719 20579 4 1786.013227 447.5105 Mitochondrial carrier homolog 2 OS=Homo sapiens OX=9606 GN=MTCH2 PE=1 SV=1 9.51 3358.6 - 399263 - - - 0.1781 - 3.275 0.603 - 244.2 1 2 0 0.0003 16 0 0 0 7.25E+06 1.01E+07 - - - 4.8923 0.9976 221125_WJC_METTL3_EV_vs_WT_F04.20581.20581.3 2.92E-05 Nov-48 K.MFIGGLSWDTSKK.D "sp|O14979|HNRDL_HUMAN,tr|A0A087WUK2|A0A087WUK2_HUMAN" 2 1468.7384 0.97 53721 20581 3 1468.739187 490.5868 Heterogeneous nuclear ribonucleoprotein D-like OS=Homo sapiens OX=9606 GN=HNRNPDL PE=1 SV=3 8.35 3358.9 - 321398 - - - 0.5113 - 2.055 0.198 - 161.4 1 2 0 0.0008 13 0 0 0 6.75E+06 6.95E+06 - - - 2.7002 1 221125_WJC_METTL3_EV_vs_WT_F04.20584.20584.3 1.41E-05 18/64 K.DK[136.11]PNPQLIYDDEIPSLK[136.11].L "sp|Q9Y2L1|RRP44_HUMAN,tr|G3V1J5|G3V1J5_HUMAN" 2 2000.0437 20.16 53722 20584 3 2000.041573 667.6885 Exosome complex exonuclease RRP44 OS=Homo sapiens OX=9606 GN=DIS3 PE=1 SV=2 4.23 3359.3 - 868814 - - - -1.075 - 2.824 0.498 - 321.7 1 2 0 -0.0022 17 0 0 0 1.78E+08 8.81E+06 - - - 6.7143 1 221125_WJC_METTL3_EV_vs_WT_F04.20586.20586.2 7.71E-11 16/32 K.IETSINLAWTAGSNNTR[166.11].F sp|Q9Y277|VDAC3_HUMAN 1 1856.9256 1.14 53724 20586 2 1856.92479 929.4701 Voltage-dependent anion-selective channel protein 3 OS=Homo sapiens OX=9606 GN=VDAC3 PE=1 SV=1 6 3359.5 - 760655 - - - -0.4416 - 3.436 0.621 - 814.5 1 2 0 -0.0008 17 0 0 0 1.61E+07 1.41E+07 - - - 6.6621 0.9999 221125_WJC_METTL3_EV_vs_WT_F04.20591.20591.3 6.22E-05 Oct-44 K.DNAADWHNLILK.W "sp|Q9BW66|CINP_HUMAN,tr|H0YN33|H0YN33_HUMAN,tr|H0YKY0|H0YKY0_HUMAN" 3 1408.7099 1.58 53729 20591 3 1408.713065 470.5772 Cyclin-dependent kinase 2-interacting protein OS=Homo sapiens OX=9606 GN=CINP PE=1 SV=1 5.21 3360.2 - 243585 - - - 2.2375 - 1.963 0.506 - 131.4 1 2 0 0.0032 12 0 0 0 3.17E+06 2.01E+06 - - - 6.0501 0.9997 221125_WJC_METTL3_EV_vs_WT_F04.20592.20592.2 1.75E-05 Dec-32 R.LSASSSISSADLFEEPR[166.11].K "sp|Q9NP61|ARFG3_HUMAN,tr|H0Y6A0|H0Y6A0_HUMAN" 2 1804.8718 0.83 53730 20592 2 1804.867167 903.4432 ADP-ribosylation factor GTPase-activating protein 3 OS=Homo sapiens OX=9606 GN=ARFGAP3 PE=1 SV=1 4.14 3360.3 - 185509 - - - -2.5908 - 2.852 0.527 - 302.9 1 2 0 -0.0047 17 0 0 0 5.25E+06 6.30E+06 - - - 5.5086 1 221125_WJC_METTL3_EV_vs_WT_F04.20594.20594.3 0.00461 14/52 K.LTLDTIFVPNTGK[136.11]K[136.11].S "sp|Q9Y277|VDAC3_HUMAN,tr|E5RJN6|E5RJN6_HUMAN,tr|E5RK27|E5RK27_HUMAN,tr|E5RFP6|E5RFP6_HUMAN,tr|E5RHZ6|E5RHZ6_HUMAN" 5 1561.905 1.35 53731 20594 3 1561.90674 521.6423 Voltage-dependent anion-selective channel protein 3 OS=Homo sapiens OX=9606 GN=VDAC3 PE=1 SV=1 8.59 3360.6 - 2.71E+06 - - - 1.0859 - 2.74 0.49 - 187.9 1 2 0 0.0017 14 0 0 0 9.07E+07 6.70E+07 - - - 6.6812 1 221125_WJC_METTL3_EV_vs_WT_F04.20597.20597.2 2.92E-09 17/36 A.ISTPDAPATQDGVESLLQK[136.11].F "sp|Q86U44|MTA70_HUMAN,tr|B4E349|B4E349_HUMAN,tr|F5H6D8|F5H6D8_HUMAN,tr|H0YFV6|H0YFV6_HUMAN,tr|B4DTN4|B4DTN4_HUMAN" 5 1977.0146 0.02 53733 20597 2 1977.013978 989.5146 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 4.03 3360.9 - 1.60E+06 - - - -0.3151 - 3.199 0.621 - 596 1 1 0 -0.0006 19 0 0 0 8.83E+06 4.77E+08 - - - 6.4864 1 221125_WJC_METTL3_EV_vs_WT_F04.20598.20598.3 0.00169 16/60 K.KPELVISYLPPGMASK.L "sp|P78347|GTF2I_HUMAN,tr|A0A494C1K3|A0A494C1K3_HUMAN" 2 1728.9484 1.57 53734 20598 3 1728.952318 577.3234 General transcription factor II-I OS=Homo sapiens OX=9606 GN=GTF2I PE=1 SV=2 8.5 3361 - 2.27E+06 - - - 2.2493 - 2.991 0.547 - 333.7 1 2 0 0.0039 16 0 0 0 2.57E+08 1.64E+08 - - - 7.4486 0.9998 221125_WJC_METTL3_EV_vs_WT_F04.20599.20599.3 5.03E-06 13/60 R.SPQVPAAQQMLNFPEK.N sp|Q92922|SMRC1_HUMAN 1 1783.8927 3.23 53735 20599 3 1783.898204 595.6382 SWI\SNF complex subunit SMARCC1 OS=Homo sapiens OX=9606 GN=SMARCC1 PE=1 SV=3 5.72 3361.1 - 487854 - - - 3.0826 - 2.652 0.457 - 232.7 1 2 0 0.0055 16 0 0 0 2.95E+07 9.11E+06 - - - 6.1361 1 221125_WJC_METTL3_EV_vs_WT_F04.20603.20603.3 3.94E-09 15/64 K.WPEVDDDSIEDLGEVK[136.11]K[136.11].- sp|O43583|DENR_HUMAN 1 1988.955 0.14 53737 20603 3 1988.958963 663.9923 Density-regulated protein OS=Homo sapiens OX=9606 GN=DENR PE=1 SV=2 3.9 3361.6 - 3.75E+06 - - - 2.0091 - 2.801 0.59 - 236.5 1 2 0 0.004 17 0 0 0 1.94E+07 1.42E+08 - - - 7.7188 0.9918 221125_WJC_METTL3_EV_vs_WT_F04.20604.20604.3 1.22E-07 14/72 A.ISTPDAPATQDGVESLLQK[136.11].F "sp|Q86U44|MTA70_HUMAN,tr|B4E349|B4E349_HUMAN,tr|F5H6D8|F5H6D8_HUMAN,tr|H0YFV6|H0YFV6_HUMAN,tr|B4DTN4|B4DTN4_HUMAN" 5 1977.0146 0.03 53738 20604 3 1977.01922 660.0121 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 4.03 3361.7 - 2.40E+06 - - - 2.3364 - 2.614 0.494 - 258.1 1 1 0 0.0046 19 0 0 0 2.39E+07 9.04E+08 - - - 6.407 1 221125_WJC_METTL3_EV_vs_WT_F04.20606.20606.3 3.08E-06 15/64 R.GTSYQSPHGIPIDLLDR[166.11].L "sp|Q9Y230|RUVB2_HUMAN,tr|M0R0Y3|M0R0Y3_HUMAN" 2 1877.9511 0.9 53740 20606 3 1877.952505 626.991 RuvB-like 2 OS=Homo sapiens OX=9606 GN=RUVBL2 PE=1 SV=3 5.21 3361.8 - 1.43E+06 - - - 0.7498 - 2.851 0.493 - 208.5 1 2 0 0.0014 17 0 0 0 3.85E+07 4.29E+07 - - - 6.6828 0.9999 221125_WJC_METTL3_EV_vs_WT_F04.20607.20607.4 5.04E-05 24/108 R.LVNAC[160.03]LAEELPHIHAFEQK.T "sp|Q9H3K6|BOLA2_HUMAN,tr|A0A087WZT3|A0A087WZT3_HUMAN" 2 2218.1205 1 53741 20607 4 2218.123995 555.5374 BolA-like protein 2 OS=Homo sapiens OX=9606 GN=BOLA2 PE=1 SV=1 5.33 3361.9 - 939502 - - - 1.5874 - 3.868 0.467 - 496.2 1 2 0 0.0035 19 0 0 0 3.91E+07 3.89E+07 - - - 3.7474 1 221125_WJC_METTL3_EV_vs_WT_F04.20609.20609.3 9.12E-07 Dec-84 R.EPFDLGEPEQSNGGFPC[160.03]TTAPK.L sp|Q99961|SH3G1_HUMAN 1 2377.0532 2.36 53743 20609 3 2377.054357 793.3584 Endophilin-A2 OS=Homo sapiens OX=9606 GN=SH3GL1 PE=1 SV=1 4 3362.2 - 578751 - - - 0.4691 - 2.729 0.529 - 123.8 1 2 0 0.0011 22 0 0 0 1.09E+07 4.62E+06 - - - 6.8177 1 221125_WJC_METTL3_EV_vs_WT_F04.20616.20616.3 3.04E-11 14/64 K.WPEVDDDSIEDLGEVKK.- sp|O43583|DENR_HUMAN 1 1972.9266 0.14 53748 20616 3 1972.926523 658.6495 Density-regulated protein OS=Homo sapiens OX=9606 GN=DENR PE=1 SV=2 3.9 3363.1 - 1.84E+06 - - - -0.0223 - 3.176 0.646 - 243.6 1 2 0 0 17 0 0 0 1.94E+07 1.41E+08 - - - 8.6617 1 221125_WJC_METTL3_EV_vs_WT_F04.20617.20617.2 1.21E-07 14/22 R.STDYGIFQINSR.Y "sp|P61626|LYSC_HUMAN,tr|A0A0B4J259|A0A0B4J259_HUMAN,tr|F8VV32|F8VV32_HUMAN" 3 1399.6732 999 53749 20617 2 1399.675855 700.8439 Lysozyme C OS=Homo sapiens OX=9606 GN=LYZ PE=1 SV=1 5.55 3363.2 - 1.55E+06 - - - 1.9019 - 2.677 0.569 - 792.3 1 2 0 0.0027 12 0 0 0 7.32E+07 0.00E+00 - - - 5.8337 0.9998 221125_WJC_METTL3_EV_vs_WT_F04.20618.20618.3 0.000235 16/60 K.K[136.11]PELVISYLPPGMASK[136.11].L "sp|P78347|GTF2I_HUMAN,tr|A0A494C1K3|A0A494C1K3_HUMAN" 2 1744.9768 1.56 53750 20618 3 1744.978412 582.6662 General transcription factor II-I OS=Homo sapiens OX=9606 GN=GTF2I PE=1 SV=2 8.5 3363.3 - 3.73E+06 - - - 0.9072 - 2.048 0.393 - 200.1 1 2 0 0.0016 16 0 0 0 2.46E+08 1.57E+08 - - - 4.7605 1 221125_WJC_METTL3_EV_vs_WT_F04.20620.20620.3 2.21E-07 Dec-64 R.GTSYQSPHGIPIDLLDR.L "sp|Q9Y230|RUVB2_HUMAN,tr|M0R0Y3|M0R0Y3_HUMAN" 2 1867.9428 0.9 53752 20620 3 1867.945772 623.6549 RuvB-like 2 OS=Homo sapiens OX=9606 GN=RUVBL2 PE=1 SV=3 5.21 3363.5 - 1.13E+06 - - - 1.5766 - 2.882 0.511 - 143.3 1 2 0 0.0029 17 0 0 0 3.85E+07 4.29E+07 - - - 6.9104 1 221125_WJC_METTL3_EV_vs_WT_F04.20621.20621.3 1.63E-11 21/72 K.YYHASLEPVDFVNAADESR.K "sp|Q9UIV8|SPB13_HUMAN,tr|F8WE70|F8WE70_HUMAN,tr|A0A0A0MQW3|A0A0A0MQW3_HUMAN" 3 2181.9967 999 53753 20621 3 2181.998857 728.3395 Serpin B13 OS=Homo sapiens OX=9606 GN=SERPINB13 PE=1 SV=2 4.31 3363.6 - 987339 - - - 0.9826 - 4.101 0.625 - 620.1 1 2 0 0.0021 19 0 0 0 1.46E+07 0.00E+00 - - - 8.9747 0.9999 221125_WJC_METTL3_EV_vs_WT_F04.20624.20624.3 7.21E-07 13/52 R.HLQLSFQEPHFYLR[166.11].C sp|P85037|FOXK1_HUMAN 1 1823.9347 1.61 53756 20624 3 1823.934403 608.9855 Forkhead box protein K1 OS=Homo sapiens OX=9606 GN=FOXK1 PE=1 SV=1 6.92 3364 - 540966 - - - -0.1404 - 2.48 0.435 - 234.9 1 2 0 -0.0003 14 0 0 0 9.85E+06 6.11E+06 - - - 5.8035 0.9967 221125_WJC_METTL3_EV_vs_WT_F04.20625.20625.4 1.32E-08 18/96 W.SLRPESLHQVSFLFSDR.G sp|P04040|CATA_HUMAN 1 2017.0381 5.89 53757 20625 4 2017.041597 505.2668 Catalase OS=Homo sapiens OX=9606 GN=CAT PE=1 SV=3 6.47 3364.1 - 458857 - - - 1.7218 - 2.617 0.556 - 278.7 1 1 0 0.0035 17 0 0 0 4.42E+06 7.50E+05 - - - 4.3985 0.9995 221125_WJC_METTL3_EV_vs_WT_F04.20626.20626.2 1.40E-05 Oct-32 R.FSPNSSNPIIVSC[160.03]GWDK.L "sp|P63244|RACK1_HUMAN,tr|H0YAM7|H0YAM7_HUMAN,tr|D6RFX4|D6RFX4_HUMAN,tr|H0YAF8|H0YAF8_HUMAN,tr|D6R9Z1|D6R9Z1_HUMAN,tr|J3KPE3|J3KPE3_HUMAN,tr|D6R9L0|D6R9L0_HUMAN,tr|D6RHH4|D6RHH4_HUMAN,tr|D6RBD0|D6RBD0_HUMAN,tr|D6RAC2|D6RAC2_HUMAN,tr|H0Y8R5|H0Y8R5_HUMAN,tr|D6REE5|D6REE5_HUMAN,tr|H0Y8W2|H0Y8W2_HUMAN" 13 1906.8883 2.16 53758 20626 2 1906.882374 954.4515 Receptor of activated protein C kinase 1 OS=Homo sapiens OX=9606 GN=RACK1 PE=1 SV=3 5.83 3364.3 - 246309 - - - -3.1329 - 2.151 0.578 - 215.6 1 2 0 -0.006 17 0 0 0 4.29E+06 1.98E+06 - - - 5.1913 0.9999 221125_WJC_METTL3_EV_vs_WT_F04.20632.20632.2 1.03E-08 16/28 K.QNGTVVQYLPTLQEK[136.11].K "sp|P35658|NU214_HUMAN,tr|A0A494BZU9|A0A494BZU9_HUMAN,tr|A0A494C1F2|A0A494C1F2_HUMAN,tr|A0A494C0J0|A0A494C0J0_HUMAN" 4 1724.9189 2.12 53762 20632 2 1724.917595 863.4667 Nuclear pore complex protein Nup214 OS=Homo sapiens OX=9606 GN=NUP214 PE=1 SV=2 6 3365 - 839540 - - - -0.7276 - 2.753 0.537 - 675.8 1 2 0 -0.0013 15 0 0 0 6.26E+07 2.95E+07 - - - 5.4966 1 221125_WJC_METTL3_EV_vs_WT_F04.20633.20633.3 3.36E-06 15/48 K.IDQHTLLQSIVNR.T sp|Q8NDV7|TNR6A_HUMAN 1 1535.842 999 53763 20633 3 1535.84266 512.9546 Trinucleotide repeat-containing gene 6A protein OS=Homo sapiens OX=9606 GN=TNRC6A PE=1 SV=2 6.74 3365.2 - 363870 - - - 0.4362 - 2.813 0.504 - 389.2 1 2 0 0.0007 13 0 0 0 7.33E+06 0.00E+00 - - - 6.9631 0.9999 221125_WJC_METTL3_EV_vs_WT_F04.20634.20634.4 2.32E-05 13/78 R.HLQLSFQEPHFYLR.C sp|P85037|FOXK1_HUMAN 1 1813.9264 1.24 53764 20634 4 1813.928658 454.4889 Forkhead box protein K1 OS=Homo sapiens OX=9606 GN=FOXK1 PE=1 SV=1 6.92 3365.3 - 302812 - - - 1.2509 - 2.537 0.465 - 176.3 1 2 0 0.0023 14 0 0 0 3.94E+06 3.18E+06 - - - 3.6116 1 221125_WJC_METTL3_EV_vs_WT_F04.20635.20635.3 2.68E-05 Nov-44 R.STDYGIFQINSR.Y "sp|P61626|LYSC_HUMAN,tr|A0A0B4J259|A0A0B4J259_HUMAN,tr|F8VV32|F8VV32_HUMAN" 3 1399.6732 999 53765 20635 3 1399.671614 467.565 Lysozyme C OS=Homo sapiens OX=9606 GN=LYZ PE=1 SV=1 5.55 3365.4 - 299419 - - - -1.1281 - 2.189 0.486 - 121.4 1 2 0 -0.0016 12 0 0 0 5.67E+06 0.00E+00 - - - 6.1296 1 221125_WJC_METTL3_EV_vs_WT_F04.20638.20638.3 2.02E-07 16/56 K.QNGTVVQYLPTLQEK.K "sp|P35658|NU214_HUMAN,tr|A0A494BZU9|A0A494BZU9_HUMAN,tr|A0A494C1F2|A0A494C1F2_HUMAN,tr|A0A494C0J0|A0A494C0J0_HUMAN" 4 1716.9046 2.45 53766 20638 3 1716.905577 573.3088 Nuclear pore complex protein Nup214 OS=Homo sapiens OX=9606 GN=NUP214 PE=1 SV=2 6 3365.8 - 1.08E+06 - - - 0.5399 - 2.959 0.521 - 255.5 1 2 0 0.0009 15 0 0 0 2.85E+07 1.17E+07 - - - 7.1792 1 221125_WJC_METTL3_EV_vs_WT_F04.20639.20639.3 4.33E-12 27/100 R.LQEALDAEMLEDEAGGGGAGPGGAC[160.03]K.A "sp|Q1KMD3|HNRL2_HUMAN,tr|H3BQZ7|H3BQZ7_HUMAN" 2 2502.1003 1.71 53767 20639 3 2502.101317 835.0407 Heterogeneous nuclear ribonucleoprotein U-like protein 2 OS=Homo sapiens OX=9606 GN=HNRNPUL2 PE=1 SV=1 3.77 3366 - 887389 - - - 0.4192 - 4.48 0.693 - 668.3 1 2 0 0.001 26 0 0 0 1.72E+07 1.01E+07 - - - 9.7161 0.9398 221125_WJC_METTL3_EV_vs_WT_F04.20642.20642.3 9.92E-06 14/60 R.DLKLDNVLLDSEGHIK.L sp|P41743|KPCI_HUMAN 1 1807.968 0.72 53770 20642 3 1807.980089 603.6633 Protein kinase C iota type OS=Homo sapiens OX=9606 GN=PRKCI PE=1 SV=2 4.66 3366.4 - 371819 - - - 6.6981 - 2.472 0.307 - 302 1 2 1 0.0121 16 0 0 0 4.95E+06 6.88E+06 - - - 4.2816 0.9957 221125_WJC_METTL3_EV_vs_WT_F04.20646.20646.3 1.48E-08 13/72 K.C[160.03]NLHMNGNVITSDQPILLR[166.11].L "sp|Q9BY77|PDIP3_HUMAN,tr|F6VRR5|F6VRR5_HUMAN" 2 2204.107 -1 53772 20646 3 2205.100261 735.7096 Polymerase delta-interacting protein 3 OS=Homo sapiens OX=9606 GN=POLDIP3 PE=1 SV=2 6.74 3366.9 - 3.94E+06 - - - 450.6583 - 2.79 0.631 - 212.3 1 2 0 0.9933 19 0 0 0 0.00E+00 0.00E+00 - - - 7.8207 1 221125_WJC_METTL3_EV_vs_WT_F04.20648.20648.3 3.18E-14 22/100 R.LQEALDAEMLEDEAGGGGAGPGGAC[160.03]K[136.11].A "sp|Q1KMD3|HNRL2_HUMAN,tr|H3BQZ7|H3BQZ7_HUMAN" 2 2510.1145 1.71 53774 20648 3 2510.112166 837.7121 Heterogeneous nuclear ribonucleoprotein U-like protein 2 OS=Homo sapiens OX=9606 GN=HNRNPUL2 PE=1 SV=1 3.77 3367.1 - 691965 - - - -0.9171 - 4.312 0.7 - 440.7 1 2 0 -0.0023 26 0 0 0 1.72E+07 1.01E+07 - - - 9.7058 0.9998 221125_WJC_METTL3_EV_vs_WT_F04.20650.20650.4 1.39E-05 18/90 R.DLK[136.11]LDNVLLDSEGHIK[136.11].L sp|P41743|KPCI_HUMAN 1 1823.9964 0.74 53776 20650 4 1823.998564 457.0064 Protein kinase C iota type OS=Homo sapiens OX=9606 GN=PRKCI PE=1 SV=2 4.66 3367.3 - 630880 - - - 1.1979 - 2.755 0.464 - 378.2 1 2 1 0.0022 16 0 0 0 4.85E+06 6.54E+06 - - - 3.621 0.9999 221125_WJC_METTL3_EV_vs_WT_F04.20651.20651.4 7.21E-08 17/90 R.DLKLDNVLLDSEGHIK.L sp|P41743|KPCI_HUMAN 1 1807.968 0.74 53777 20651 4 1807.967823 452.9993 Protein kinase C iota type OS=Homo sapiens OX=9606 GN=PRKCI PE=1 SV=2 4.66 3367.5 - 569372 - - - -0.0863 - 3.138 0.55 - 303.1 1 2 1 -0.0002 16 0 0 0 4.85E+06 6.54E+06 - - - 4.416 0.9998 221125_WJC_METTL3_EV_vs_WT_F04.20652.20652.3 5.09E-05 14/64 K.ANSFTVSSVAAPSWLHR[166.11].F "sp|Q00341|VIGLN_HUMAN,tr|A0A024R4E5|A0A024R4E5_HUMAN,tr|H7C0A4|H7C0A4_HUMAN,tr|H0Y394|H0Y394_HUMAN" 4 1838.9303 1.12 53778 20652 3 1838.927657 613.984 Vigilin OS=Homo sapiens OX=9606 GN=HDLBP PE=1 SV=2 9.8 3367.6 - 358238 - - - -1.4378 - 2.383 0.348 - 196.7 1 2 0 -0.0026 17 0 0 0 2.64E+07 2.35E+07 - - - 4.6129 0.9987 221125_WJC_METTL3_EV_vs_WT_F04.20653.20653.3 7.24E-09 16/64 R.GREGPVQFEEDPFGLDK.F "sp|Q13573|SNW1_HUMAN,tr|G3V4X8|G3V4X8_HUMAN" 2 1918.9061 0.54 53779 20653 3 1918.916202 640.6426 SNW domain-containing protein 1 OS=Homo sapiens OX=9606 GN=SNW1 PE=1 SV=1 4.18 3367.7 - 346637 - - - 5.2608 - 3.246 0.545 - 320.2 1 2 1 0.0101 17 0 0 0 1.21E+07 2.25E+07 - - - 7.5879 0.9997 221125_WJC_METTL3_EV_vs_WT_F04.20662.20662.4 8.27E-05 14/84 K.FFVTLLEAQADYHRK.A sp|Q68EM7|RHG17_HUMAN 1 1836.9523 1.5 53786 20662 4 1836.952304 460.2453 Rho GTPase-activating protein 17 OS=Homo sapiens OX=9606 GN=ARHGAP17 PE=1 SV=1 6.75 3368.8 - 475676 - - - 0.0191 - 2.656 0.358 - 209.9 1 2 0 0 15 0 0 0 3.09E+06 2.06E+06 - - - 2.6915 1 221125_WJC_METTL3_EV_vs_WT_F04.20664.20664.2 1.23E-09 26-Oct K.NANC[160.03]TSDFEEYFAK.R "sp|O60315|ZEB2_HUMAN,tr|U3KPV5|U3KPV5_HUMAN,tr|E7ESP8|E7ESP8_HUMAN,tr|E7EUW9|E7EUW9_HUMAN,tr|A0JP08|A0JP08_HUMAN,tr|A0A1B0GW50|A0A1B0GW50_HUMAN,tr|A0A1B0GV02|A0A1B0GV02_HUMAN,tr|A0A1X7SC99|A0A1X7SC99_HUMAN,tr|A0A1B0GVV8|A0A1B0GVV8_HUMAN" 9 1694.6883 4.84 53788 20664 2 1694.684016 848.3514 Zinc finger E-box-binding homeobox 2 OS=Homo sapiens OX=9606 GN=ZEB2 PE=1 SV=1 4.14 3369.1 - 331329 - - - -2.4996 - 2.528 0.771 - 336.7 1 2 0 -0.0042 14 0 0 0 2.50E+06 5.17E+05 - - - 7.0616 1 221125_WJC_METTL3_EV_vs_WT_F04.20668.20668.3 1.74E-09 14/60 K.IEWLESHQDADIEDFK[136.11].A "sp|P11021|BIP_HUMAN,tr|A0A7P0TB36|A0A7P0TB36_HUMAN,tr|A0A7P0TAI0|A0A7P0TAI0_HUMAN" 3 1981.9149 1.1 53790 20668 3 1981.914081 661.6456 Endoplasmic reticulum chaperone BiP OS=Homo sapiens OX=9606 GN=HSPA5 PE=1 SV=2 4.01 3369.6 - 8.35E+06 - - - -0.4067 - 3.473 0.596 - 207.9 1 2 0 -0.0008 16 0 0 0 8.45E+07 7.65E+07 - - - 8.3791 0.9987 221125_WJC_METTL3_EV_vs_WT_F04.20670.20670.3 0.00079 Dec-76 K.ALPC[160.03]IVDVRDEQQISAAVEK.A sp|Q6YN16|HSDL2_HUMAN 1 2240.1471 1.76 53792 20670 3 2240.151474 747.723 Hydroxysteroid dehydrogenase-like protein 2 OS=Homo sapiens OX=9606 GN=HSDL2 PE=1 SV=1 4.32 3369.8 - 1.37E+06 - - - 1.9606 - 2.184 0.392 - 157 1 2 1 0.0044 20 0 0 0 1.38E+07 7.86E+06 - - - 4.8043 1 221125_WJC_METTL3_EV_vs_WT_F04.20673.20673.2 4.89E-12 26/40 R.GQVGGEINVEMDAAPGVDLSR.L "sp|Q04695|K1C17_HUMAN,tr|K7EPJ9|K7EPJ9_HUMAN,tr|K7ESE1|K7ESE1_HUMAN,tr|F5GWP8|F5GWP8_HUMAN" 4 2113.011 999 53795 20673 2 2113.017836 1057.5128 "Keratin, type I cytoskeletal 17 OS=Homo sapiens OX=9606 GN=KRT17 PE=1 SV=2" 3.92 3370.1 - 889233 - - - 3.2432 - 4.289 0.696 - 1538.1 1 2 0 0.0069 21 0 0 0 1.79E+08 0.00E+00 - - - 7.7593 0.9997 221125_WJC_METTL3_EV_vs_WT_F04.20674.20674.4 3.29E-05 17/96 K.MKPLMGVIYVPLTDKEK.Q "sp|P22061|PIMT_HUMAN,tr|F6S8N6|F6S8N6_HUMAN,tr|A0A3F2YNX8|A0A3F2YNX8_HUMAN,tr|A0A0A0MRJ6|A0A0A0MRJ6_HUMAN" 4 1961.073 0.61 53796 20674 4 1961.073716 491.2755 Protein-L-isoaspartate(D-aspartate) O-methyltransferase OS=Homo sapiens OX=9606 GN=PCMT1 PE=1 SV=4 8.19 3370.2 - 671720 - - - 0.3763 - 3.047 0.442 - 216.6 1 2 1 0.0007 17 0 0 0 6.22E+06 1.01E+07 - - - 3.4598 1 221125_WJC_METTL3_EV_vs_WT_F04.20675.20675.2 7.53E-12 13/44 F.GGFGGFGGGAGGGDGGILTANEK.S sp|P35527|K1C9_HUMAN 1 1951.9024 999 53797 20675 2 1951.904898 976.9585 "Keratin, type I cytoskeletal 9 OS=Homo sapiens OX=9606 GN=KRT9 PE=1 SV=3" 4.37 3370.4 - 521506 - - - 1.2706 - 3.314 0.584 - 350.8 1 1 0 0.0025 23 0 0 0 6.14E+06 0.00E+00 - - - 6.2994 0.9999 221125_WJC_METTL3_EV_vs_WT_F04.20676.20676.3 0.00278 Dec-48 K.MFIGGLSWDTTK[136.11]K[136.11].D "sp|Q14103|HNRPD_HUMAN,tr|H0Y8G5|H0Y8G5_HUMAN,tr|D6RF44|D6RF44_HUMAN,tr|D6RD83|D6RD83_HUMAN,tr|D6RBQ9|D6RBQ9_HUMAN,tr|D6RAF8|D6RAF8_HUMAN,tr|H0YA96|H0YA96_HUMAN" 7 1498.7825 2.36 53798 20676 3 1498.782628 500.6014 Heterogeneous nuclear ribonucleoprotein D0 OS=Homo sapiens OX=9606 GN=HNRNPD PE=1 SV=1 8.35 3370.5 - 490003 - - - 0.0947 - 2.282 0.382 - 143.3 1 2 0 0.0001 13 0 0 0 1.12E+07 4.74E+06 - - - 5.0358 1 221125_WJC_METTL3_EV_vs_WT_F04.20677.20677.2 1.65E-06 30-Oct K.IEWLESHQDADIEDFK[136.11].A "sp|P11021|BIP_HUMAN,tr|A0A7P0TB36|A0A7P0TB36_HUMAN,tr|A0A7P0TAI0|A0A7P0TAI0_HUMAN" 3 1981.9149 0.77 53799 20677 2 1981.904289 991.9647 Endoplasmic reticulum chaperone BiP OS=Homo sapiens OX=9606 GN=HSPA5 PE=1 SV=2 4.01 3370.6 - 287313 - - - -5.3474 - 2.614 0.671 - 249.4 1 2 0 -0.0106 16 0 0 0 1.07E+06 1.38E+06 - - - 6.356 1 221125_WJC_METTL3_EV_vs_WT_F04.20682.20682.3 8.37E-06 19/56 R.ELAQQVQQVAAEYC[160.03]R.A "sp|P17844|DDX5_HUMAN,tr|A0A7I2V5F5|A0A7I2V5F5_HUMAN,tr|J3KRZ1|J3KRZ1_HUMAN,tr|A0A7I2V507|A0A7I2V507_HUMAN,tr|J3KTA4|J3KTA4_HUMAN,tr|A0A0G2JLI4|A0A0G2JLI4_HUMAN,tr|A0A7I2V2S0|A0A7I2V2S0_HUMAN,tr|J3QRQ7|J3QRQ7_HUMAN" 8 1791.8574 1.86 53802 20682 3 1791.855377 598.2931 Probable ATP-dependent RNA helicase DDX5 OS=Homo sapiens OX=9606 GN=DDX5 PE=1 SV=1 4.53 3371.2 - 952000 - - - -1.1195 - 3.279 0.534 - 544.5 1 2 0 -0.002 15 0 0 0 1.18E+08 6.35E+07 - - - 7.5917 1 221125_WJC_METTL3_EV_vs_WT_F04.20683.20683.3 0.000422 21/68 R.DVQIGDIVTVGEC[160.03]R[166.11]PLSK[136.11].T "sp|P62280|RS11_HUMAN,tr|M0R1H5|M0R1H5_HUMAN" 2 2003.0476 1.04 53803 20683 3 2003.048349 668.6898 40S ribosomal protein S11 OS=Homo sapiens OX=9606 GN=RPS11 PE=1 SV=3 4.56 3371.2 - 6.79E+06 - - - 0.351 - 3.714 0.528 - 464.7 1 2 0 0.0007 18 0 0 0 4.58E+08 4.41E+08 - - - 7.6938 1 221125_WJC_METTL3_EV_vs_WT_F04.20686.20686.3 1.80E-07 14/56 R.LQINQSIIFC[160.03]NSSQR.V sp|P26196|DDX6_HUMAN 1 1806.9047 0.78 53806 20686 3 1806.90419 603.3088 Probable ATP-dependent RNA helicase DDX6 OS=Homo sapiens OX=9606 GN=DDX6 PE=1 SV=2 8.25 3371.5 - 1.30E+06 - - - -0.264 - 2.994 0.546 - 261.5 1 2 0 -0.0005 15 0 0 0 9.68E+06 1.24E+07 - - - 7.4887 1 221125_WJC_METTL3_EV_vs_WT_F04.20691.20691.3 3.32E-08 18/84 K.VDVGGSEPASLSYLSFEGATK[136.11]R[166.11].N sp|Q9NQT5|EXOS3_HUMAN 1 2287.1451 1.77 53811 20691 3 2287.149748 763.389 Exosome complex component RRP40 OS=Homo sapiens OX=9606 GN=EXOSC3 PE=1 SV=3 4.68 3372.1 - 387715 - - - 2.027 - 3.226 0.577 - 229.2 1 2 0 0.0046 22 0 0 0 1.41E+07 7.96E+06 - - - 7.7485 1 221125_WJC_METTL3_EV_vs_WT_F04.20692.20692.2 5.58E-09 18/30 K.K[136.11]PELVISYLPPGMASK[136.11].L "sp|P78347|GTF2I_HUMAN,tr|A0A494C1K3|A0A494C1K3_HUMAN" 2 1744.9768 0.71 53812 20692 2 1744.984031 873.4957 General transcription factor II-I OS=Homo sapiens OX=9606 GN=GTF2I PE=1 SV=2 8.5 3372.2 - 304426 - - - 4.1273 - 3.537 0.627 - 813.4 1 2 0 0.0072 16 0 0 0 7.65E+06 1.07E+07 - - - 6.7756 1 221125_WJC_METTL3_EV_vs_WT_F04.20697.20697.3 2.49E-09 19/68 R.DVQIGDIVTVGEC[160.03]RPLSK.T "sp|P62280|RS11_HUMAN,tr|M0R1H5|M0R1H5_HUMAN" 2 1985.0252 1.03 53815 20697 3 1985.025167 662.6823 40S ribosomal protein S11 OS=Homo sapiens OX=9606 GN=RPS11 PE=1 SV=3 4.56 3372.9 - 1.82E+07 - - - -0.0045 - 3.741 0.586 - 360.4 1 2 0 0 18 0 0 0 4.56E+08 4.41E+08 - - - 8.3586 1 221125_WJC_METTL3_EV_vs_WT_F04.20698.20698.2 6.24E-10 17/28 K.QNGTVVQYLPTLQEK.K "sp|P35658|NU214_HUMAN,tr|A0A494BZU9|A0A494BZU9_HUMAN,tr|A0A494C1F2|A0A494C1F2_HUMAN,tr|A0A494C0J0|A0A494C0J0_HUMAN" 4 1716.9046 2.12 53816 20698 2 1716.903712 859.4596 Nuclear pore complex protein Nup214 OS=Homo sapiens OX=9606 GN=NUP214 PE=1 SV=2 6 3373 - 2.52E+06 - - - -0.5463 - 2.965 0.605 - 724.5 1 2 0 -0.0009 15 0 0 0 6.26E+07 2.95E+07 - - - 6.1814 1 221125_WJC_METTL3_EV_vs_WT_F04.20699.20699.3 7.92E-05 Sep-64 K.ANSFTVSSVAAPSWLHR.F "sp|Q00341|VIGLN_HUMAN,tr|A0A024R4E5|A0A024R4E5_HUMAN,tr|H7C0A4|H7C0A4_HUMAN,tr|H0Y394|H0Y394_HUMAN" 4 1828.922 1.12 53817 20699 3 1828.924282 610.648 Vigilin OS=Homo sapiens OX=9606 GN=HDLBP PE=1 SV=2 9.8 3373.1 - 2.74E+06 - - - 1.2308 - 2.513 0.483 - 84.8 1 2 0 0.0023 17 0 0 0 2.64E+07 2.35E+07 - - - 6.2523 1 221125_WJC_METTL3_EV_vs_WT_F04.20700.20700.3 2.74E-09 16/72 R.MDSFDEDLARPSGLLAQER.K "sp|Q9Y2W1|TR150_HUMAN,tr|A0A3B3ITZ9|A0A3B3ITZ9_HUMAN" 2 2149.011 2 53818 20700 3 2149.011391 717.3443 Thyroid hormone receptor-associated protein 3 OS=Homo sapiens OX=9606 GN=THRAP3 PE=1 SV=2 4.1 3373.2 - 2.18E+06 - - - 0.1899 - 3.082 0.612 - 234.9 1 2 0 0.0004 19 0 0 0 2.01E+07 1.00E+07 - - - 8.1284 1 221125_WJC_METTL3_EV_vs_WT_F04.20701.20701.3 7.12E-08 17/56 R.LQINQSIIFC[160.03]NSSQR[166.11].V sp|P26196|DDX6_HUMAN 1 1816.9129 0.78 53819 20701 3 1816.913395 606.6449 Probable ATP-dependent RNA helicase DDX6 OS=Homo sapiens OX=9606 GN=DDX6 PE=1 SV=2 8.25 3373.3 - 1.36E+06 - - - 0.2521 - 3.405 0.51 - 488.2 1 2 0 0.0005 15 0 0 0 9.68E+06 1.24E+07 - - - 7.423 1 221125_WJC_METTL3_EV_vs_WT_F04.20703.20703.2 5.71E-11 14/30 R.GENSWFSTQVDTVATK[136.11].V "sp|P08195|4F2_HUMAN,tr|A0A7P0TAN7|A0A7P0TAN7_HUMAN,tr|J3KPF3|J3KPF3_HUMAN,tr|F5H056|F5H056_HUMAN,tr|H0YH36|H0YH36_HUMAN,tr|F5GZI0|F5GZI0_HUMAN,tr|A0A7P0T8U7|A0A7P0T8U7_HUMAN,tr|A0A7P0T9F7|A0A7P0T9F7_HUMAN,tr|A0A7P0TBF8|A0A7P0TBF8_HUMAN,tr|A0A7P0T8F1|A0A7P0T8F1_HUMAN,tr|A0A7P0Z4A0|A0A7P0Z4A0_HUMAN,tr|F5GZS6|F5GZS6_HUMAN,tr|A0A7P0Z4P5|A0A7P0Z4P5_HUMAN,tr|A0A7P0TAS6|A0A7P0TAS6_HUMAN" 14 1776.841 1.35 53821 20703 2 1776.835078 889.4278 4F2 cell-surface antigen heavy chain OS=Homo sapiens OX=9606 GN=SLC3A2 PE=1 SV=3 4.37 3373.5 - 913756 - - - -3.3295 - 3.366 0.61 - 660.5 1 2 0 -0.0059 16 0 0 0 2.17E+07 1.61E+07 - - - 6.5286 1 221125_WJC_METTL3_EV_vs_WT_F04.20704.20704.3 0.00515 21/88 K.AVTSGLPGDTALLLPPSPR[166.11]PSPR[166.11].V "sp|Q6W2J9|BCOR_HUMAN,tr|H7BZ37|H7BZ37_HUMAN,tr|H7C2V9|H7C2V9_HUMAN,tr|H7BYY2|H7BYY2_HUMAN,tr|H7C231|H7C231_HUMAN" 5 2318.2861 2.07 53822 20704 3 2318.28262 773.7693 BCL-6 corepressor OS=Homo sapiens OX=9606 GN=BCOR PE=1 SV=1 9.64 3373.6 - 826364 - - - -1.5102 - 3.529 0.447 - 303.3 1 2 0 -0.0035 23 0 0 0 1.47E+07 7.10E+06 - - - 6.4809 1 221125_WJC_METTL3_EV_vs_WT_F04.20706.20706.2 8.54E-07 17/28 R.LQINQSIIFC[160.03]NSSQR[166.11].V sp|P26196|DDX6_HUMAN 1 1816.9129 1 53824 20706 2 1816.913501 909.4637 Probable ATP-dependent RNA helicase DDX6 OS=Homo sapiens OX=9606 GN=DDX6 PE=1 SV=2 8.25 3373.9 - 731714 - - - 0.3104 - 3.521 0.606 - 943.4 1 2 0 0.0006 15 0 0 0 6.80E+06 6.79E+06 - - - 6.6114 0.9927 221125_WJC_METTL3_EV_vs_WT_F04.20707.20707.3 0.167 Oct-48 R.DITLFHAMDTLHK.N "sp|Q13330|MTA1_HUMAN,tr|H0Y4T7|H0Y4T7_HUMAN,tr|E7ESY4|E7ESY4_HUMAN" 3 1540.7708 1.8 53825 20707 3 1540.769873 514.5975 Metastasis-associated protein MTA1 OS=Homo sapiens OX=9606 GN=MTA1 PE=1 SV=2 5.98 3374 - 729707 - - - -0.601 - 1.786 0.169 - 65.9 1 2 0 -0.0009 13 0 0 0 5.99E+06 3.33E+06 - - - 1.9964 1 221125_WJC_METTL3_EV_vs_WT_F04.20708.20708.3 3.90E-06 16/88 K.IYSQSTLSLSTVANEAHNNLGVK[136.11].R sp|Q9P1Y5|CAMP3_HUMAN 1 2453.2642 1.25 53826 20708 3 2453.265764 818.762 Calmodulin-regulated spectrin-associated protein 3 OS=Homo sapiens OX=9606 GN=CAMSAP3 PE=1 SV=2 6.75 3374.1 - 665652 - - - 0.651 - 2.936 0.509 - 165.6 1 2 0 0.0016 23 0 0 0 4.74E+06 3.79E+06 - - - 6.7411 1 221125_WJC_METTL3_EV_vs_WT_F04.20709.20709.2 3.42E-07 18/34 R.DVQIGDIVTVGEC[160.03]R[166.11]PLSK[136.11].T "sp|P62280|RS11_HUMAN,tr|M0R1H5|M0R1H5_HUMAN" 2 2003.0476 1.09 53827 20709 2 2003.045398 1002.5311 40S ribosomal protein S11 OS=Homo sapiens OX=9606 GN=RPS11 PE=1 SV=3 4.56 3374.2 - 647456 - - - -1.1223 - 3.435 0.601 - 913 1 2 0 -0.0022 18 0 0 0 2.15E+07 1.98E+07 - - - 6.5132 1 221125_WJC_METTL3_EV_vs_WT_F04.20711.20711.2 9.10E-08 20/34 R.DVQIGDIVTVGEC[160.03]RPLSK.T "sp|P62280|RS11_HUMAN,tr|M0R1H5|M0R1H5_HUMAN" 2 1985.0252 1.09 53829 20711 2 1985.021222 993.5199 40S ribosomal protein S11 OS=Homo sapiens OX=9606 GN=RPS11 PE=1 SV=3 4.56 3374.5 - 552150 - - - -1.9919 - 3.854 0.66 - 1128.8 1 2 0 -0.004 18 0 0 0 2.15E+07 1.98E+07 - - - 7.2314 1 221125_WJC_METTL3_EV_vs_WT_F04.20712.20712.2 1.40E-08 21/34 K.TVTNAVVTVPAYFNDSQR[166.11].Q "sp|P11142|HSP7C_HUMAN,tr|E9PQQ4|E9PQQ4_HUMAN,tr|E9PN89|E9PN89_HUMAN,tr|E9PLF4|E9PLF4_HUMAN,tr|E9PI65|E9PI65_HUMAN,tr|E9PK54|E9PK54_HUMAN,tr|E9PQK7|E9PQK7_HUMAN" 7 1990.9988 0.16 53830 20712 2 1990.996578 996.5067 Heat shock cognate 71 kDa protein OS=Homo sapiens OX=9606 GN=HSPA8 PE=1 SV=1 5.5 3374.6 - 467400 - - - -1.1035 - 3.302 0.602 - 968.7 1 2 0 -0.0022 18 0 0 0 1.16E+09 7.18E+09 - - - 6.4235 0.9998 221125_WJC_METTL3_EV_vs_WT_F04.20713.20713.2 1.40E-05 26-Sep R.QEINFWVEC[160.03]QSQGK.L sp|Q96P63|SPB12_HUMAN 1 1751.7937 999 53831 20713 2 1751.795454 876.9041 Serpin B12 OS=Homo sapiens OX=9606 GN=SERPINB12 PE=1 SV=1 4.53 3374.8 - 403621 - - - 0.9898 - 1.956 0.545 - 231.4 1 2 0 0.0017 14 0 0 0 7.39E+06 0.00E+00 - - - 4.7494 1 221125_WJC_METTL3_EV_vs_WT_F04.20720.20720.3 1.93E-09 17/56 R.ELAQQVQQVAAEYC[160.03]R[166.11].A "sp|P17844|DDX5_HUMAN,tr|A0A7I2V5F5|A0A7I2V5F5_HUMAN,tr|J3KRZ1|J3KRZ1_HUMAN,tr|A0A7I2V507|A0A7I2V507_HUMAN,tr|J3KTA4|J3KTA4_HUMAN,tr|A0A0G2JLI4|A0A0G2JLI4_HUMAN,tr|A0A7I2V2S0|A0A7I2V2S0_HUMAN,tr|J3QRQ7|J3QRQ7_HUMAN" 8 1801.8657 1.89 53836 20720 3 1801.863335 601.6292 Probable ATP-dependent RNA helicase DDX5 OS=Homo sapiens OX=9606 GN=DDX5 PE=1 SV=1 4.53 3375.5 - 5.82E+06 - - - -1.2864 - 3.251 0.608 - 414.9 1 2 0 -0.0023 15 0 0 0 1.16E+08 6.14E+07 - - - 8.3943 1 221125_WJC_METTL3_EV_vs_WT_F04.20721.20721.2 3.55E-07 14/28 R.ELAQQVQQVAAEYC[160.03]R.A "sp|P17844|DDX5_HUMAN,tr|A0A7I2V5F5|A0A7I2V5F5_HUMAN,tr|J3KRZ1|J3KRZ1_HUMAN,tr|A0A7I2V507|A0A7I2V507_HUMAN,tr|J3KTA4|J3KTA4_HUMAN,tr|A0A0G2JLI4|A0A0G2JLI4_HUMAN,tr|A0A7I2V2S0|A0A7I2V2S0_HUMAN,tr|J3QRQ7|J3QRQ7_HUMAN" 8 1791.8574 1.66 53837 20721 2 1791.85579 896.936 Probable ATP-dependent RNA helicase DDX5 OS=Homo sapiens OX=9606 GN=DDX5 PE=1 SV=1 4.53 3375.6 - 4.49E+06 - - - -0.889 - 3.156 0.557 - 780.3 1 2 0 -0.0016 15 0 0 0 7.45E+07 4.48E+07 - - - 5.9801 1 221125_WJC_METTL3_EV_vs_WT_F04.20722.20722.3 2.10E-10 18/64 R.EGIVTATEQEVKEDIAK.L "sp|Q12931|TRAP1_HUMAN,tr|I3L0K7|I3L0K7_HUMAN" 2 1858.9524 1.5 53838 20722 3 1858.950797 620.6581 "Heat shock protein 75 kDa, mitochondrial OS=Homo sapiens OX=9606 GN=TRAP1 PE=1 SV=3" 4.25 3375.7 - 2.28E+06 - - - -0.8559 - 4.013 0.606 - 640.5 1 2 1 -0.0016 17 0 0 0 2.78E+07 1.86E+07 - - - 8.8063 1 221125_WJC_METTL3_EV_vs_WT_F04.20723.20723.3 3.23E-12 20/72 K.K[136.11]PVVDC[160.03]VVSVPC[160.03]FYTDAER[166.11].R "sp|P34932|HSP74_HUMAN,tr|A0A087WTS8|A0A087WTS8_HUMAN,tr|A0A087WYC1|A0A087WYC1_HUMAN" 3 2258.083 0.03 53839 20723 3 2258.081781 753.7016 Heat shock 70 kDa protein 4 OS=Homo sapiens OX=9606 GN=HSPA4 PE=1 SV=4 4.56 3375.8 - 2.13E+06 - - - -0.5602 - 3.416 0.671 - 407.4 1 2 0 -0.0013 19 0 0 0 9.51E+05 2.89E+07 - - - 9.0387 0.9964 221125_WJC_METTL3_EV_vs_WT_F04.20724.20724.3 2.75E-08 14/52 K.LSTDDLNSLIAHAH.R "sp|Q16891|MIC60_HUMAN,tr|B9A067|B9A067_HUMAN,tr|C9J406|C9J406_HUMAN,tr|H7C463|H7C463_HUMAN" 4 1505.7474 - 53840 20724 3 1505.745765 502.9231 MICOS complex subunit MIC60 OS=Homo sapiens OX=9606 GN=IMMT PE=1 SV=1 5.05 3375.9 - 1.74E+06 - - - -1.0998 - 2.533 0.482 - 304.1 1 1 0 -0.0017 14 0 0 0 - - - - - 6.3833 0.9951 221125_WJC_METTL3_EV_vs_WT_F04.20726.20726.3 2.17E-05 14/52 Q.EQISNLEAQITDVR.Q "sp|P35527|K1C9_HUMAN,tr|K7EQQ3|K7EQQ3_HUMAN" 2 1614.8213 21.26 53842 20726 3 1614.820469 539.281 "Keratin, type I cytoskeletal 9 OS=Homo sapiens OX=9606 GN=KRT9 PE=1 SV=3" 4.14 3376.1 - 1.05E+06 - - - -0.5233 - 2.332 0.466 - 254.8 1 1 0 -0.0008 14 0 0 0 5.33E+06 2.51E+05 - - - 5.9854 1 221125_WJC_METTL3_EV_vs_WT_F04.20727.20727.4 1.13E-07 17/78 K.GHPFFEGVDWEHIR.E sp|Q9Y2H1|ST38L_HUMAN 1 1724.8059 3.36 53843 20727 4 1724.803422 432.2088 Serine\threonine-protein kinase 38-like OS=Homo sapiens OX=9606 GN=STK38L PE=1 SV=3 5.27 3376.2 - 874735 - - - -1.4593 - 2.629 0.509 - 220.9 1 2 0 -0.0025 14 0 0 0 4.36E+07 1.30E+07 - - - 4.0074 0.9794 221125_WJC_METTL3_EV_vs_WT_F04.20728.20728.3 0.000549 Dec-60 R.AEK[136.11]TEVLSEDLLQIER[166.11].R "sp|Q68EM7|RHG17_HUMAN,tr|I3L1S9|I3L1S9_HUMAN,tr|I3L4P0|I3L4P0_HUMAN,tr|C9IZD3|C9IZD3_HUMAN" 4 1890.0065 0.79 53844 20728 3 1889.995835 631.0094 Rho GTPase-activating protein 17 OS=Homo sapiens OX=9606 GN=ARHGAP17 PE=1 SV=1 4.25 3376.3 - 692167 - - - -5.6391 - 2.485 0.339 - 164.8 1 2 1 -0.0107 16 0 0 0 3.61E+06 4.55E+06 - - - 4.6522 1 221125_WJC_METTL3_EV_vs_WT_F04.20729.20729.2 4.40E-09 18/36 R.ELQSQISDTSVVLSMDNSR.S "sp|P05787|K2C8_HUMAN,sp|P08729|K2C7_HUMAN,tr|F8VUG2|F8VUG2_HUMAN,tr|A0A1W2PRP1|A0A1W2PRP1_HUMAN" 4 2108.0056 1.16 53845 20729 2 2107.995607 1055.0101 "Keratin, type II cytoskeletal 8 OS=Homo sapiens OX=9606 GN=KRT8 PE=1 SV=7" 4.03 3376.5 - 364461 - - - -4.7229 - 3.576 0.704 - 900.6 1 2 0 -0.01 19 0 0 0 5.98E+06 5.17E+06 - - - 7.3704 1 221125_WJC_METTL3_EV_vs_WT_F04.20733.20733.3 0.000356 21/72 R.MDSFDEDLAR[166.11]PSGLLAQER[166.11].K "sp|Q9Y2W1|TR150_HUMAN,tr|A0A3B3ITZ9|A0A3B3ITZ9_HUMAN" 2 2169.0275 2.99 53847 20733 3 2169.023883 724.0165 Thyroid hormone receptor-associated protein 3 OS=Homo sapiens OX=9606 GN=THRAP3 PE=1 SV=2 4.1 3377 - 3.06E+07 - - - -1.6782 - 3.281 0.603 - 618.8 1 2 0 -0.0036 19 0 0 0 1.06E+10 3.56E+09 - - - 8.1809 0.9994 221125_WJC_METTL3_EV_vs_WT_F04.20735.20735.3 1.09E-09 20/72 R.GC[160.03]VNYEGADR[166.11]VEFVIETAR[166.11].Q sp|Q7Z5L9|I2BP2_HUMAN 1 2204.0435 1.41 53849 20735 3 2204.032879 735.6884 Interferon regulatory factor 2-binding protein 2 OS=Homo sapiens OX=9606 GN=IRF2BP2 PE=1 SV=2 4.41 3377.1 - 4.58E+06 - - - -4.822 - 3.018 0.639 - 535.6 1 2 1 -0.0106 19 0 0 0 6.09E+07 4.33E+07 - - - 8.375 1 221125_WJC_METTL3_EV_vs_WT_F04.20736.20736.3 8.34E-15 22/96 R.FAHPADSTMIDTNDNTVTVC[160.03]MDYIK.G "sp|Q9NR56|MBNL1_HUMAN,tr|H7C4T5|H7C4T5_HUMAN,tr|Q86VM6|Q86VM6_HUMAN,tr|H7C4Y1|H7C4Y1_HUMAN,tr|A0A0A0MQX8|A0A0A0MQX8_HUMAN,tr|C9JCX1|C9JCX1_HUMAN,tr|C9JP00|C9JP00_HUMAN" 7 2858.2561 1.89 53850 20736 3 2858.253977 953.7593 Muscleblind-like protein 1 OS=Homo sapiens OX=9606 GN=MBNL1 PE=1 SV=2 4.13 3377.2 - 2.28E+06 - - - -0.7487 - 4.344 0.747 - 378.3 1 2 0 -0.0021 25 0 0 0 1.79E+07 9.48E+06 - - - 10.2469 0.9999 221125_WJC_METTL3_EV_vs_WT_F04.20741.20741.4 9.80E-06 15/78 K.GHPFFEGVDWEHIR[166.11].E sp|Q9Y2H1|ST38L_HUMAN 1 1734.8142 3.36 53855 20741 4 1734.808786 434.7108 Serine\threonine-protein kinase 38-like OS=Homo sapiens OX=9606 GN=STK38L PE=1 SV=3 5.27 3377.9 - 859214 - - - -3.126 - 2.446 0.534 - 179.9 1 2 0 -0.0054 14 0 0 0 4.36E+07 1.30E+07 - - - 4.198 1 221125_WJC_METTL3_EV_vs_WT_F04.20743.20743.3 1.10E-09 19/64 K.EIEGEEIEIVLAKPPDK.K "sp|O43390|HNRPR_HUMAN,tr|B4DT28|B4DT28_HUMAN,tr|A0A6Q8PH35|A0A6Q8PH35_HUMAN,tr|A0A286YEZ8|A0A286YEZ8_HUMAN" 4 1908.0092 1.09 53857 20743 3 1908.011813 637.0103 Heterogeneous nuclear ribonucleoprotein R OS=Homo sapiens OX=9606 GN=HNRNPR PE=1 SV=1 4.14 3378.1 - 626323 - - - 1.3826 - 2.979 0.577 - 434.7 1 2 0 0.0026 17 0 0 0 1.16E+07 1.07E+07 - - - 7.7299 0.9999 221125_WJC_METTL3_EV_vs_WT_F04.20750.20750.2 1.10E-06 15/36 R.MDSFDEDLARPSGLLAQER.K "sp|Q9Y2W1|TR150_HUMAN,tr|A0A3B3ITZ9|A0A3B3ITZ9_HUMAN" 2 2149.011 3.2 53862 20750 2 2149.00806 1075.5128 Thyroid hormone receptor-associated protein 3 OS=Homo sapiens OX=9606 GN=THRAP3 PE=1 SV=2 4.1 3378.9 - 4.07E+06 - - - -1.3602 - 2.518 0.582 - 121.8 1 2 0 -0.0029 19 0 0 0 3.01E+08 9.43E+07 - - - 5.6091 0.9994 221125_WJC_METTL3_EV_vs_WT_F04.20752.20752.2 1.13E-08 17/36 R.MDSFDEDLAR[166.11]PSGLLAQER[166.11].K "sp|Q9Y2W1|TR150_HUMAN,tr|A0A3B3ITZ9|A0A3B3ITZ9_HUMAN" 2 2169.0275 3.2 53864 20752 2 2169.020754 1085.521 Thyroid hormone receptor-associated protein 3 OS=Homo sapiens OX=9606 GN=THRAP3 PE=1 SV=2 4.1 3379.1 - 1.67E+06 - - - -3.1208 - 2.737 0.431 - 173 1 2 0 -0.0068 19 0 0 0 3.01E+08 9.43E+07 - - - 4.6977 1 221125_WJC_METTL3_EV_vs_WT_F04.20758.20758.3 7.39E-16 21/80 R.GQVGGEINVEMDAAPGVDLSR.L "sp|Q04695|K1C17_HUMAN,tr|K7EPJ9|K7EPJ9_HUMAN,tr|K7ESE1|K7ESE1_HUMAN,tr|F5GWP8|F5GWP8_HUMAN" 4 2113.011 999 53868 20758 3 2113.009747 705.3443 "Keratin, type I cytoskeletal 17 OS=Homo sapiens OX=9606 GN=KRT17 PE=1 SV=2" 3.92 3379.8 - 1.12E+07 - - - -0.5849 - 3.862 0.715 - 370.9 1 2 0 -0.0012 21 0 0 0 3.09E+08 0.00E+00 - - - 9.7506 1 221125_WJC_METTL3_EV_vs_WT_F04.20760.20760.4 3.59E-08 18/108 R.MDSFDEDLARPSGLLAQER.K "sp|Q9Y2W1|TR150_HUMAN,tr|A0A3B3ITZ9|A0A3B3ITZ9_HUMAN" 2 2149.011 1.84 53870 20760 4 2149.008159 538.26 Thyroid hormone receptor-associated protein 3 OS=Homo sapiens OX=9606 GN=THRAP3 PE=1 SV=2 4.1 3380 - 1.44E+06 - - - -1.3141 - 3.461 0.616 - 162.1 1 2 0 -0.0028 19 0 0 0 3.44E+07 1.87E+07 - - - 5.0069 1 221125_WJC_METTL3_EV_vs_WT_F04.20761.20761.2 7.29E-09 17/34 K.TVTNAVVTVPAYFNDSQR.Q "sp|P11142|HSP7C_HUMAN,tr|E9PQQ4|E9PQQ4_HUMAN,tr|E9PN89|E9PN89_HUMAN,tr|E9PLF4|E9PLF4_HUMAN,tr|E9PI65|E9PI65_HUMAN,tr|E9PK54|E9PK54_HUMAN,tr|E9PQK7|E9PQK7_HUMAN" 7 1980.9905 0.16 53871 20761 2 1980.986701 991.5025 Heat shock cognate 71 kDa protein OS=Homo sapiens OX=9606 GN=HSPA8 PE=1 SV=1 5.5 3380.1 - 1.36E+06 - - - -1.9203 - 2.926 0.557 - 458.7 1 2 0 -0.0038 18 0 0 0 1.16E+09 7.17E+09 - - - 5.7934 1 221125_WJC_METTL3_EV_vs_WT_F04.20763.20763.3 1.51E-06 16/56 R.DQDLTQEIAMEHFVK[136.11].K "sp|Q9ULX6|AKP8L_HUMAN,tr|A0A7P0TAE3|A0A7P0TAE3_HUMAN" 2 1810.8651 11.53 53873 20763 3 1810.868421 604.629 A-kinase anchor protein 8-like OS=Homo sapiens OX=9606 GN=AKAP8L PE=1 SV=4 4.31 3380.4 - 772630 - - - 1.8339 - 3.177 0.494 - 435.4 1 2 0 0.0033 15 0 0 0 6.24E+07 5.41E+06 - - - 7.063 0.9999 221125_WJC_METTL3_EV_vs_WT_F04.20769.20769.3 1.82E-08 14/44 R.AR[166.11]FEELC[160.03]SDLFR[166.11].S "sp|P48741|HSP77_HUMAN,sp|P0DMV8|HS71A_HUMAN,sp|P0DMV9|HS71B_HUMAN,sp|P17066|HSP76_HUMAN,tr|V9GZ37|V9GZ37_HUMAN,tr|A0A0G2JIW1|A0A0G2JIW1_HUMAN" 6 1561.7462 0.08 53877 20769 3 1561.743283 521.5893 Putative heat shock 70 kDa protein 7 OS=Homo sapiens OX=9606 GN=HSPA7 PE=5 SV=2 4.68 3381.1 - 2.27E+06 - - - -1.8697 - 2.901 0.602 - 389 1 2 1 -0.0029 12 0 0 0 2.97E+07 3.56E+08 - - - 8.2031 0.9993 221125_WJC_METTL3_EV_vs_WT_F04.20770.20770.3 4.76E-06 18/48 K.SK[136.11]DSLVDIIGIC[160.03]K[136.11].S "sp|P27694|RFA1_HUMAN,tr|I3L4R8|I3L4R8_HUMAN" 2 1462.8036 1.1 53878 20770 3 1462.80104 488.6085 Replication protein A 70 kDa DNA-binding subunit OS=Homo sapiens OX=9606 GN=RPA1 PE=1 SV=2 5.68 3381.2 - 1.96E+06 - - - -1.761 - 2.381 0.386 - 558.2 1 2 1 -0.0026 13 0 0 0 2.75E+07 2.51E+07 - - - 5.1949 0.9997 221125_WJC_METTL3_EV_vs_WT_F04.20772.20772.3 9.24E-05 16/48 K.SKDSLVDIIGIC[160.03]K.S "sp|P27694|RFA1_HUMAN,tr|I3L4R8|I3L4R8_HUMAN" 2 1446.7752 1.1 53880 20772 3 1446.771228 483.2657 Replication protein A 70 kDa DNA-binding subunit OS=Homo sapiens OX=9606 GN=RPA1 PE=1 SV=2 5.68 3381.4 - 1.23E+06 - - - -2.7565 - 3.11 0.499 - 421.5 1 2 1 -0.004 13 0 0 0 2.75E+07 2.51E+07 - - - 7.1785 0.9999 221125_WJC_METTL3_EV_vs_WT_F04.20774.20774.3 2.89E-05 19/60 K.LTVIAEQIQHLQEQAR[166.11].K sp|Q9BV19|CA050_HUMAN 1 1886.0249 1.78 53882 20774 3 1886.029163 629.6823 Uncharacterized protein C1orf50 OS=Homo sapiens OX=9606 GN=C1orf50 PE=1 SV=2 5.4 3381.7 - 1.05E+06 - - - 2.2444 - 2.827 0.464 - 277.4 1 2 0 0.0042 16 0 0 0 5.94E+07 3.33E+07 - - - 6.3785 0.9963 221125_WJC_METTL3_EV_vs_WT_F04.20779.20779.4 3.74E-05 26/108 K.ISSIQSIVPALEIANAHRK.P "sp|P10809|CH60_HUMAN,tr|A0A7I2V2X6|A0A7I2V2X6_HUMAN,tr|A0A7I2YQK6|A0A7I2YQK6_HUMAN,tr|A0A7I2V599|A0A7I2V599_HUMAN,tr|A0A7I2YQ71|A0A7I2YQ71_HUMAN,tr|A0A7I2V5M1|A0A7I2V5M1_HUMAN,tr|A0A7I2V5K3|A0A7I2V5K3_HUMAN,tr|A0A7I2V369|A0A7I2V369_HUMAN" 8 2046.1586 1.3 53885 20779 4 2046.155914 512.5469 "60 kDa heat shock protein, mitochondrial OS=Homo sapiens OX=9606 GN=HSPD1 PE=1 SV=2" 8.75 3382.2 - 2.40E+06 - - - -1.2995 - 3.735 0.5 - 610 1 1 0 -0.0027 19 0 0 0 8.31E+08 6.40E+08 - - - 4.023 1 221125_WJC_METTL3_EV_vs_WT_F04.20785.20785.3 5.34E-10 20/64 K.YDGFDC[160.03]VYGLELNKDER.V sp|Q9Y657|SPIN1_HUMAN 1 2091.9208 2.82 53889 20785 3 2091.918912 698.3142 Spindlin-1 OS=Homo sapiens OX=9606 GN=SPIN1 PE=1 SV=3 4.11 3382.9 - 5.26E+06 - - - -0.8887 - 3.849 0.75 - 554.5 1 2 1 -0.0019 17 0 0 0 8.50E+07 3.02E+07 - - - 10.3062 1 221125_WJC_METTL3_EV_vs_WT_F04.20786.20786.3 2.42E-11 19/60 K.K[136.11]DC[160.03]EVVMMIGLPGAGK[136.11].T "sp|Q00839|HNRPU_HUMAN,tr|A0A1W2PQL0|A0A1W2PQL0_HUMAN,tr|A0A1W2PPL4|A0A1W2PPL4_HUMAN,tr|A0A1W2PQ74|A0A1W2PQ74_HUMAN,tr|Q5RI18|Q5RI18_HUMAN,tr|A0A1W2PP35|A0A1W2PP35_HUMAN,tr|A0A1W2PPS1|A0A1W2PPS1_HUMAN,tr|A0A1W2PRZ7|A0A1W2PRZ7_HUMAN,tr|A0A1W2PPH7|A0A1W2PPH7_HUMAN,tr|A0A1W2PQD4|A0A1W2PQD4_HUMAN,tr|A0A1W2PP34|A0A1W2PP34_HUMAN,tr|A0A1X7SBS1|A0A1X7SBS1_HUMAN" 12 1719.8693 0.99 53890 20786 3 1719.868332 574.297 Heterogeneous nuclear ribonucleoprotein U OS=Homo sapiens OX=9606 GN=HNRNPU PE=1 SV=6 6.06 3382.9 - 2.95E+06 - - - -0.5454 - 3.227 0.551 - 440.6 1 2 0 -0.0009 16 0 0 0 3.04E+09 3.07E+09 - - - 7.6889 1 221125_WJC_METTL3_EV_vs_WT_F04.20787.20787.3 1.29E-06 18/60 K.KDC[160.03]EVVMMIGLPGAGK.T "sp|Q00839|HNRPU_HUMAN,tr|A0A1W2PQL0|A0A1W2PQL0_HUMAN,tr|A0A1W2PPL4|A0A1W2PPL4_HUMAN,tr|A0A1W2PQ74|A0A1W2PQ74_HUMAN,tr|Q5RI18|Q5RI18_HUMAN,tr|A0A1W2PP35|A0A1W2PP35_HUMAN,tr|A0A1W2PPS1|A0A1W2PPS1_HUMAN,tr|A0A1W2PRZ7|A0A1W2PRZ7_HUMAN,tr|A0A1W2PPH7|A0A1W2PPH7_HUMAN,tr|A0A1W2PQD4|A0A1W2PQD4_HUMAN,tr|A0A1W2PP34|A0A1W2PP34_HUMAN,tr|A0A1X7SBS1|A0A1X7SBS1_HUMAN" 12 1703.8409 0.99 53891 20787 3 1703.837541 568.9542 Heterogeneous nuclear ribonucleoprotein U OS=Homo sapiens OX=9606 GN=HNRNPU PE=1 SV=6 6.06 3383 - 2.43E+06 - - - -1.9538 - 3.408 0.591 - 349.5 1 2 0 -0.0033 16 0 0 0 3.05E+09 3.07E+09 - - - 8.2742 0.9918 221125_WJC_METTL3_EV_vs_WT_F04.20788.20788.4 1.31E-06 29/108 K.ISSIQSIVPALEIANAHR[166.11]K[136.11].P "sp|P10809|CH60_HUMAN,tr|A0A7I2V2X6|A0A7I2V2X6_HUMAN,tr|A0A7I2YQK6|A0A7I2YQK6_HUMAN,tr|A0A7I2V599|A0A7I2V599_HUMAN,tr|A0A7I2YQ71|A0A7I2YQ71_HUMAN,tr|A0A7I2V5M1|A0A7I2V5M1_HUMAN,tr|A0A7I2V5K3|A0A7I2V5K3_HUMAN,tr|A0A7I2V369|A0A7I2V369_HUMAN" 8 2064.181 1.3 53892 20788 4 2064.174837 517.0525 "60 kDa heat shock protein, mitochondrial OS=Homo sapiens OX=9606 GN=HSPD1 PE=1 SV=2" 8.75 3383.1 - 2.33E+06 - - - -3.0065 - 4.233 0.527 - 713.5 1 1 0 -0.0062 19 0 0 0 8.31E+08 6.40E+08 - - - 4.2994 1 221125_WJC_METTL3_EV_vs_WT_F04.20789.20789.2 4.89E-08 16/22 R.AR[166.11]FEELC[160.03]SDLFR[166.11].S "sp|P48741|HSP77_HUMAN,sp|P0DMV8|HS71A_HUMAN,sp|P0DMV9|HS71B_HUMAN,sp|P17066|HSP76_HUMAN,tr|V9GZ37|V9GZ37_HUMAN,tr|A0A0G2JIW1|A0A0G2JIW1_HUMAN" 6 1561.7462 0.03 53893 20789 2 1561.742663 781.8804 Putative heat shock 70 kDa protein 7 OS=Homo sapiens OX=9606 GN=HSPA7 PE=5 SV=2 4.68 3383.2 - 1.80E+06 - - - -2.2667 - 2.836 0.626 - 390.1 1 2 1 -0.0035 12 0 0 0 2.29E+06 8.42E+07 - - - 6.4062 0.9996 221125_WJC_METTL3_EV_vs_WT_F04.20792.20792.3 2.33E-07 13/72 R.MDSFDEDLAR[166.11]PSGLLAQER.K "sp|Q9Y2W1|TR150_HUMAN,tr|A0A3B3ITZ9|A0A3B3ITZ9_HUMAN" 2 2159.0193 - 53894 20792 3 2159.011187 720.6804 Thyroid hormone receptor-associated protein 3 OS=Homo sapiens OX=9606 GN=THRAP3 PE=1 SV=2 4.1 3383.6 - 3.17E+06 - - - -3.736 - 2.251 0.471 - 227.4 2 2 0 -0.0081 19 0 0 0 - - - - - 5.643 1 221125_WJC_METTL3_EV_vs_WT_F04.20800.20800.2 0.00359 22/30 K.KDC[160.03]EVVMMIGLPGAGK.T "sp|Q00839|HNRPU_HUMAN,tr|A0A1W2PQL0|A0A1W2PQL0_HUMAN,tr|A0A1W2PPL4|A0A1W2PPL4_HUMAN,tr|A0A1W2PQ74|A0A1W2PQ74_HUMAN,tr|Q5RI18|Q5RI18_HUMAN,tr|A0A1W2PP35|A0A1W2PP35_HUMAN,tr|A0A1W2PPS1|A0A1W2PPS1_HUMAN,tr|A0A1W2PRZ7|A0A1W2PRZ7_HUMAN,tr|A0A1W2PPH7|A0A1W2PPH7_HUMAN,tr|A0A1W2PQD4|A0A1W2PQD4_HUMAN,tr|A0A1W2PP34|A0A1W2PP34_HUMAN,tr|A0A1X7SBS1|A0A1X7SBS1_HUMAN" 12 1703.8409 1.86 53901 20800 2 1703.839869 852.9277 Heterogeneous nuclear ribonucleoprotein U OS=Homo sapiens OX=9606 GN=HNRNPU PE=1 SV=6 6.06 3384.3 - 566236 - - - -0.5875 - 3.857 0.582 - 1188.6 1 2 0 -0.001 16 0 0 0 5.70E+08 3.06E+08 - - - 6.6581 0.9997 221125_WJC_METTL3_EV_vs_WT_F04.20803.20803.3 1.22E-05 13/52 K.EQIGKVDEIFGQLR.D sp|Q9NY12|GAR1_HUMAN 1 1630.8679 1.4 53902 20803 3 1630.865045 544.6299 H\ACA ribonucleoprotein complex subunit 1 OS=Homo sapiens OX=9606 GN=GAR1 PE=1 SV=1 4.68 3384.7 - 3.36E+06 - - - -1.7328 - 2.439 0.45 - 189.7 1 2 1 -0.0028 14 0 0 0 8.98E+07 6.44E+07 - - - 5.9257 1 221125_WJC_METTL3_EV_vs_WT_F04.20804.20804.3 1.63E-09 16/68 K.QQLSAEELDAQLDAYNAR.M "sp|Q86V81|THOC4_HUMAN,tr|E9PB61|E9PB61_HUMAN" 2 2033.9654 0.82 53903 20804 3 2033.96631 678.9957 THO complex subunit 4 OS=Homo sapiens OX=9606 GN=ALYREF PE=1 SV=3 3.92 3384.8 - 2.97E+06 - - - 0.441 - 3.398 0.561 - 267.1 1 2 0 0.0009 18 0 0 0 3.20E+09 3.89E+09 - - - 7.8402 0.9993 221125_WJC_METTL3_EV_vs_WT_F04.20807.20807.2 3.19E-06 13/26 K.GDGPVQGIINFEQK.E sp|P00441|SODC_HUMAN 1 1500.7573 1.99 53906 20807 2 1500.753161 751.3859 Superoxide dismutase [Cu-Zn] OS=Homo sapiens OX=9606 GN=SOD1 PE=1 SV=2 4.37 3385.2 - 1.14E+06 - - - -2.73 - 2.559 0.362 - 640.1 1 2 0 -0.0041 14 0 0 0 1.11E+08 5.54E+07 - - - 4.0714 0.9999 221125_WJC_METTL3_EV_vs_WT_F04.20808.20808.3 1.22E-06 20/72 R.QAVLGAGLPISTPC[160.03]TTINK.V "sp|P24752|THIL_HUMAN,tr|A0A5F9ZHJ7|A0A5F9ZHJ7_HUMAN,tr|A0A5F9ZHH9|A0A5F9ZHH9_HUMAN,tr|A0A5F9ZHJ0|A0A5F9ZHJ0_HUMAN,tr|A0A5F9ZHL1|A0A5F9ZHL1_HUMAN,tr|H0YEL7|H0YEL7_HUMAN" 6 1940.0401 1.17 53907 20808 3 1940.036603 647.6873 "Acetyl-CoA acetyltransferase, mitochondrial OS=Homo sapiens OX=9606 GN=ACAT1 PE=1 SV=1" 8.22 3385.3 - 1.00E+06 - - - -1.8015 - 2.774 0.449 - 240.1 1 2 0 -0.0035 19 0 0 0 8.65E+07 7.41E+07 - - - 6.0516 1 221125_WJC_METTL3_EV_vs_WT_F04.20811.20811.3 2.60E-09 19/64 K.YDGFDC[160.03]VYGLELNK[136.11]DER[166.11].V sp|Q9Y657|SPIN1_HUMAN 1 2109.9432 2.82 53908 20811 3 2109.939894 704.3217 Spindlin-1 OS=Homo sapiens OX=9606 GN=SPIN1 PE=1 SV=3 4.11 3385.7 - 2.98E+06 - - - -1.5863 - 3.366 0.697 - 445.1 1 2 1 -0.0033 17 0 0 0 8.50E+07 3.02E+07 - - - 9.3762 1 221125_WJC_METTL3_EV_vs_WT_F04.20812.20812.2 1.64E-07 17/34 K.QQLSAEELDAQLDAYNAR.M "sp|Q86V81|THOC4_HUMAN,tr|E9PB61|E9PB61_HUMAN" 2 2033.9654 0.77 53909 20812 2 2033.961408 1017.99 THO complex subunit 4 OS=Homo sapiens OX=9606 GN=ALYREF PE=1 SV=3 3.92 3385.8 - 2.92E+06 - - - -1.9691 - 3.671 0.656 - 1039.7 1 2 0 -0.004 18 0 0 0 1.49E+09 1.93E+09 - - - 7.0822 1 221125_WJC_METTL3_EV_vs_WT_F04.20816.20816.3 1.07E-07 23/72 R.QAVLGAGLPISTPC[160.03]TTINK[136.11].V "sp|P24752|THIL_HUMAN,tr|A0A5F9ZHJ7|A0A5F9ZHJ7_HUMAN,tr|A0A5F9ZHH9|A0A5F9ZHH9_HUMAN,tr|A0A5F9ZHJ0|A0A5F9ZHJ0_HUMAN,tr|A0A5F9ZHL1|A0A5F9ZHL1_HUMAN,tr|H0YEL7|H0YEL7_HUMAN" 6 1948.0543 1.13 53913 20816 3 1948.050255 650.3587 "Acetyl-CoA acetyltransferase, mitochondrial OS=Homo sapiens OX=9606 GN=ACAT1 PE=1 SV=1" 8.22 3386.3 - 1.34E+06 - - - -2.0754 - 3.766 0.533 - 727.7 1 2 0 -0.004 19 0 0 0 8.65E+07 7.63E+07 - - - 7.7391 1 221125_WJC_METTL3_EV_vs_WT_F04.20818.20818.2 4.04E-11 14/30 K.NEAPEGNLGDFAEFQR[166.11].R sp|Q9UKN8|TF3C4_HUMAN 1 1802.8099 1.78 53915 20818 2 1802.801781 902.4122 General transcription factor 3C polypeptide 4 OS=Homo sapiens OX=9606 GN=GTF3C4 PE=1 SV=2 4 3386.6 - 506107 - - - -4.5102 - 2.868 0.662 - 670 1 2 0 -0.0081 16 0 0 0 6.85E+06 3.84E+06 - - - 6.5183 1 221125_WJC_METTL3_EV_vs_WT_F04.20821.20821.3 1.23E-07 17/68 K.QQLSAEELDAQLDAYNAR[166.11].M "sp|Q86V81|THOC4_HUMAN,tr|E9PB61|E9PB61_HUMAN" 2 2043.9737 0.82 53916 20821 3 2043.973108 682.3318 THO complex subunit 4 OS=Homo sapiens OX=9606 GN=ALYREF PE=1 SV=3 3.92 3387 - 3.73E+07 - - - -0.2813 - 3.279 0.601 - 334.9 1 2 0 -0.0006 18 0 0 0 3.19E+09 3.89E+09 - - - 8.1975 1 221125_WJC_METTL3_EV_vs_WT_F04.20823.20823.2 4.19E-13 17/34 K.QQLSAEELDAQLDAYNAR[166.11].M "sp|Q86V81|THOC4_HUMAN,tr|E9PB61|E9PB61_HUMAN" 2 2043.9737 0.77 53918 20823 2 2043.96925 1022.9941 THO complex subunit 4 OS=Homo sapiens OX=9606 GN=ALYREF PE=1 SV=3 3.92 3387.1 - 1.21E+07 - - - -2.1688 - 3.715 0.708 - 978.7 1 2 0 -0.0044 18 0 0 0 1.49E+09 1.93E+09 - - - 7.4954 0.9999 221125_WJC_METTL3_EV_vs_WT_F04.20825.20825.3 6.41E-06 16/60 R.GILDDLQLDSTAHTAK.Q sp|Q5VT06|CE350_HUMAN 1 1696.8632 999 53920 20825 3 1696.859391 566.6283 Centrosome-associated protein 350 OS=Homo sapiens OX=9606 GN=CEP350 PE=1 SV=1 4.41 3387.2 - 1.86E+06 - - - -2.2324 - 2.479 0.504 - 154.3 1 2 0 -0.0038 16 0 0 0 4.52E+07 0.00E+00 - - - 6.4875 1 221125_WJC_METTL3_EV_vs_WT_F04.20833.20833.2 2.99E-12 23/30 K.K[136.11]DC[160.03]EVVMMIGLPGAGK[136.11].T "sp|Q00839|HNRPU_HUMAN,tr|A0A1W2PQL0|A0A1W2PQL0_HUMAN,tr|A0A1W2PPL4|A0A1W2PPL4_HUMAN,tr|A0A1W2PQ74|A0A1W2PQ74_HUMAN,tr|Q5RI18|Q5RI18_HUMAN,tr|A0A1W2PP35|A0A1W2PP35_HUMAN,tr|A0A1W2PPS1|A0A1W2PPS1_HUMAN,tr|A0A1W2PRZ7|A0A1W2PRZ7_HUMAN,tr|A0A1W2PPH7|A0A1W2PPH7_HUMAN,tr|A0A1W2PQD4|A0A1W2PQD4_HUMAN,tr|A0A1W2PP34|A0A1W2PP34_HUMAN,tr|A0A1X7SBS1|A0A1X7SBS1_HUMAN" 12 1719.8693 1.71 53925 20833 2 1719.867754 860.9419 Heterogeneous nuclear ribonucleoprotein U OS=Homo sapiens OX=9606 GN=HNRNPU PE=1 SV=6 6.06 3388.1 - 3.52E+06 - - - -0.8815 - 4.615 0.68 - 1260.8 1 2 0 -0.0015 16 0 0 0 5.24E+08 3.06E+08 - - - 7.8229 0.9996 221125_WJC_METTL3_EV_vs_WT_F04.20840.20840.3 1.94E-06 17/56 K.DR[166.11]EGFFTNGLTLGAK[136.11].K "sp|P35080|PROF2_HUMAN,tr|C9JQ45|C9JQ45_HUMAN,tr|G5E9Q6|G5E9Q6_HUMAN,tr|C9J2N0|C9J2N0_HUMAN,tr|C9J0J7|C9J0J7_HUMAN,tr|C9J712|C9J712_HUMAN" 6 1642.8434 0.94 53930 20840 3 1642.837992 548.6217 Profilin-2 OS=Homo sapiens OX=9606 GN=PFN2 PE=1 SV=3 6.07 3388.9 - 2.41E+06 - - - -3.2858 - 2.333 0.563 - 299.2 1 2 1 -0.0054 15 0 0 0 3.14E+07 3.32E+07 - - - 7.0259 0.9996 221125_WJC_METTL3_EV_vs_WT_F04.20841.20841.3 4.31E-05 15/52 K.EQIGK[136.11]VDEIFGQLR[166.11].D sp|Q9NY12|GAR1_HUMAN 1 1648.8903 1.4 53931 20841 3 1648.88731 550.6374 H\ACA ribonucleoprotein complex subunit 1 OS=Homo sapiens OX=9606 GN=GAR1 PE=1 SV=1 4.68 3389 - 1.86E+06 - - - -1.8382 - 2.467 0.448 - 271.7 1 2 1 -0.003 14 0 0 0 8.98E+07 6.44E+07 - - - 5.9337 1 221125_WJC_METTL3_EV_vs_WT_F04.20842.20842.2 7.34E-07 20/38 F.GGGFGGGFGGDGGLLSGNEK.V "sp|P13645|K1C10_HUMAN,tr|A0A1B0GVI3|A0A1B0GVI3_HUMAN" 2 1738.7911 106.83 53932 20842 2 1738.783483 870.4028 "Keratin, type I cytoskeletal 10 OS=Homo sapiens OX=9606 GN=KRT10 PE=1 SV=6" 4.37 3389.1 - 1.50E+06 - - - -4.3674 - 3.692 0.629 - 1046.1 1 1 0 -0.0076 20 0 0 0 4.53E+07 4.24E+05 - - - 6.8957 1 221125_WJC_METTL3_EV_vs_WT_F04.20847.20847.3 0.00625 16/68 K.SGGLSVEVC[160.03]GPALSQQWK[136.11].F sp|Q10471|GALT2_HUMAN 1 1909.9447 1.66 53935 20847 3 1909.942394 637.6555 Polypeptide N-acetylgalactosaminyltransferase 2 OS=Homo sapiens OX=9606 GN=GALNT2 PE=1 SV=1 5.72 3389.8 - 666893 - - - -1.2325 - 3.188 0.504 - 321.1 1 2 0 -0.0024 18 0 0 0 2.84E+07 1.71E+07 - - - 7.0455 1 221125_WJC_METTL3_EV_vs_WT_F04.20848.20848.2 3.11E-08 19/36 R.QAVLGAGLPISTPC[160.03]TTINK.V "sp|P24752|THIL_HUMAN,tr|A0A5F9ZHJ7|A0A5F9ZHJ7_HUMAN,tr|A0A5F9ZHH9|A0A5F9ZHH9_HUMAN,tr|A0A5F9ZHJ0|A0A5F9ZHJ0_HUMAN,tr|A0A5F9ZHL1|A0A5F9ZHL1_HUMAN,tr|H0YEL7|H0YEL7_HUMAN" 6 1940.0401 1.94 53936 20848 2 1940.03673 971.0273 "Acetyl-CoA acetyltransferase, mitochondrial OS=Homo sapiens OX=9606 GN=ACAT1 PE=1 SV=1" 8.22 3389.9 - 1.63E+06 - - - -1.736 - 3.581 0.577 - 786.3 1 2 0 -0.0034 19 0 0 0 5.18E+07 2.67E+07 - - - 6.4379 0.9995 221125_WJC_METTL3_EV_vs_WT_F04.20849.20849.2 7.15E-06 14/26 K.GDGPVQGIINFEQK[136.11].E sp|P00441|SODC_HUMAN 1 1508.7715 1.99 53937 20849 2 1508.76829 755.393 Superoxide dismutase [Cu-Zn] OS=Homo sapiens OX=9606 GN=SOD1 PE=1 SV=2 4.37 3390 - 1.33E+06 - - - -2.0991 - 2.513 0.361 - 720.9 1 2 0 -0.0032 14 0 0 0 1.11E+08 5.54E+07 - - - 4.0188 1 221125_WJC_METTL3_EV_vs_WT_F04.20850.20850.2 2.66E-06 20/36 R.QAVLGAGLPISTPC[160.03]TTINK[136.11].V "sp|P24752|THIL_HUMAN,tr|A0A5F9ZHJ7|A0A5F9ZHJ7_HUMAN,tr|A0A5F9ZHH9|A0A5F9ZHH9_HUMAN,tr|A0A5F9ZHJ0|A0A5F9ZHJ0_HUMAN,tr|A0A5F9ZHL1|A0A5F9ZHL1_HUMAN,tr|H0YEL7|H0YEL7_HUMAN" 6 1948.0543 1.94 53938 20850 2 1948.053306 975.0344 "Acetyl-CoA acetyltransferase, mitochondrial OS=Homo sapiens OX=9606 GN=ACAT1 PE=1 SV=1" 8.22 3390.1 - 1.14E+06 - - - -0.5092 - 3.437 0.542 - 967.7 1 2 0 -0.001 19 0 0 0 5.18E+07 2.67E+07 - - - 6.0792 1 221125_WJC_METTL3_EV_vs_WT_F04.20851.20851.2 5.96E-05 17/34 K.SGGLSVEVC[160.03]GPALSQQWK.F sp|Q10471|GALT2_HUMAN 1 1901.9305 2 53939 20851 2 1901.93066 951.9726 Polypeptide N-acetylgalactosaminyltransferase 2 OS=Homo sapiens OX=9606 GN=GALNT2 PE=1 SV=1 5.72 3390.3 - 740083 - - - 0.0589 - 3.51 0.643 - 753.3 1 2 0 0.0001 18 0 0 0 3.38E+07 1.69E+07 - - - 6.8772 0.9936 221125_WJC_METTL3_EV_vs_WT_F04.20856.20856.3 0.000224 17/56 K.DREGFFTNGLTLGAK.K "sp|P35080|PROF2_HUMAN,tr|C9JQ45|C9JQ45_HUMAN,tr|G5E9Q6|G5E9Q6_HUMAN,tr|C9J2N0|C9J2N0_HUMAN,tr|C9J0J7|C9J0J7_HUMAN,tr|C9J712|C9J712_HUMAN" 6 1624.8209 0.94 53942 20856 3 1624.817171 542.6142 Profilin-2 OS=Homo sapiens OX=9606 GN=PFN2 PE=1 SV=3 6.07 3390.9 - 1.80E+06 - - - -2.3073 - 2.018 0.295 - 293.8 1 2 1 -0.0037 15 0 0 0 3.11E+07 3.32E+07 - - - 3.66 1 221125_WJC_METTL3_EV_vs_WT_F04.20862.20862.3 4.92E-05 19/60 K.KPELVISYLPPGMASK.L "sp|P78347|GTF2I_HUMAN,tr|A0A494C1K3|A0A494C1K3_HUMAN" 2 1728.9484 1.57 53946 20862 3 1728.946106 577.3234 General transcription factor II-I OS=Homo sapiens OX=9606 GN=GTF2I PE=1 SV=2 8.5 3391.7 - 2.87E+06 - - - -1.3436 - 3.257 0.532 - 446.6 1 2 0 -0.0023 16 0 0 0 1.11E+08 7.09E+07 - - - 7.5004 1 221125_WJC_METTL3_EV_vs_WT_F04.20867.20867.3 2.19E-07 18/68 K.SGGLSVEVC[160.03]GPALSQQWK.F sp|Q10471|GALT2_HUMAN 1 1901.9305 1.68 53951 20867 3 1901.931511 634.9841 Polypeptide N-acetylgalactosaminyltransferase 2 OS=Homo sapiens OX=9606 GN=GALNT2 PE=1 SV=1 5.72 3392.3 - 904491 - - - 0.5063 - 3.442 0.518 - 403.1 1 2 0 0.001 18 0 0 0 2.88E+07 1.71E+07 - - - 7.3928 1 221125_WJC_METTL3_EV_vs_WT_F04.20869.20869.3 1.52E-09 18/68 K.TVTNAVVTVPAYFNDSQR.Q "sp|P11142|HSP7C_HUMAN,tr|E9PQQ4|E9PQQ4_HUMAN,tr|E9PN89|E9PN89_HUMAN,tr|E9PLF4|E9PLF4_HUMAN,tr|E9PI65|E9PI65_HUMAN,tr|E9PK54|E9PK54_HUMAN,tr|E9PQK7|E9PQK7_HUMAN" 7 1980.9905 0.16 53952 20869 3 1980.989457 661.3374 Heat shock cognate 71 kDa protein OS=Homo sapiens OX=9606 GN=HSPA8 PE=1 SV=1 5.5 3392.5 - 4.56E+07 - - - -0.529 - 3.195 0.605 - 357.7 1 2 0 -0.001 18 0 0 0 2.57E+09 1.57E+10 - - - 8.1773 0.9998 221125_WJC_METTL3_EV_vs_WT_F04.20873.20873.3 0.000124 15/56 R.QYYTLLNQAPDMLHR.F "sp|Q13283|G3BP1_HUMAN,tr|E5RH00|E5RH00_HUMAN,tr|E5RH42|E5RH42_HUMAN,tr|A0A7I2V4Y8|A0A7I2V4Y8_HUMAN,tr|A0A7I2V3C4|A0A7I2V3C4_HUMAN,tr|A0A7P0P2U7|A0A7P0P2U7_HUMAN,tr|A0A7I2V2S5|A0A7I2V2S5_HUMAN,tr|A0A7I2YQU8|A0A7I2YQU8_HUMAN,tr|E5RJU8|E5RJU8_HUMAN,tr|A0A7I2V651|A0A7I2V651_HUMAN,tr|E5RIF8|E5RIF8_HUMAN,tr|A0A7I2YQN9|A0A7I2YQN9_HUMAN" 12 1861.9145 0.99 53953 20873 3 1861.911042 621.6454 Ras GTPase-activating protein-binding protein 1 OS=Homo sapiens OX=9606 GN=G3BP1 PE=1 SV=1 6.74 3393.1 - 750806 - - - -1.8588 - 2.246 0.392 - 262.5 1 2 0 -0.0035 15 0 0 0 7.92E+07 7.99E+07 - - - 5.0208 0.9929 221125_WJC_METTL3_EV_vs_WT_F04.20875.20875.2 4.86E-06 16-Dec V.PAYFNDSQR[166.11].Q "sp|P38646|GRP75_HUMAN,sp|P54652|HSP72_HUMAN,sp|P0DMV8|HS71A_HUMAN,sp|P34931|HS71L_HUMAN,sp|P11142|HSP7C_HUMAN,sp|P0DMV9|HS71B_HUMAN,sp|P17066|HSP76_HUMAN,tr|E9PQQ4|E9PQQ4_HUMAN,tr|H0Y8K0|H0Y8K0_HUMAN,tr|E9PN89|E9PN89_HUMAN,tr|A0A7I2V2S7|A0A7I2V2S7_HUMAN,tr|A0A7I2V2G2|A0A7I2V2G2_HUMAN,tr|E9PLF4|E9PLF4_HUMAN,tr|Q53FA3|Q53FA3_HUMAN,tr|E9PI65|E9PI65_HUMAN,tr|E9PK54|E9PK54_HUMAN,tr|A0A7I2V3F7|A0A7I2V3F7_HUMAN,tr|A0A7I2YQB2|A0A7I2YQB2_HUMAN,tr|E9PQK7|E9PQK7_HUMAN,tr|A0A0G2JIW1|A0A0G2JIW1_HUMAN,tr|D6RCD7|D6RCD7_HUMAN" 21 1106.502 0.29 53954 20875 2 1106.50167 554.2583 "Stress-70 protein, mitochondrial OS=Homo sapiens OX=9606 GN=HSPA9 PE=1 SV=2" 6.26 3393.3 - 4.68E+06 - - - -0.3362 - 2.211 0.481 - 565.7 1 1 0 -0.0004 9 0 0 0 5.78E+07 1.98E+08 - - - 4.889 1 221125_WJC_METTL3_EV_vs_WT_F04.20876.20876.3 6.37E-05 14/60 K.K[136.11]DC[160.03]EVVMMIGLPGAGK.T "sp|Q00839|HNRPU_HUMAN,tr|A0A1W2PQL0|A0A1W2PQL0_HUMAN,tr|A0A1W2PPL4|A0A1W2PPL4_HUMAN,tr|A0A1W2PQ74|A0A1W2PQ74_HUMAN,tr|Q5RI18|Q5RI18_HUMAN,tr|A0A1W2PP35|A0A1W2PP35_HUMAN,tr|A0A1W2PPS1|A0A1W2PPS1_HUMAN,tr|A0A1W2PRZ7|A0A1W2PRZ7_HUMAN,tr|A0A1W2PPH7|A0A1W2PPH7_HUMAN,tr|A0A1W2PQD4|A0A1W2PQD4_HUMAN,tr|A0A1W2PP34|A0A1W2PP34_HUMAN,tr|A0A1X7SBS1|A0A1X7SBS1_HUMAN" 12 1711.8551 - 53955 20876 3 1711.854926 571.6256 Heterogeneous nuclear ribonucleoprotein U OS=Homo sapiens OX=9606 GN=HNRNPU PE=1 SV=6 6.06 3393.3 - 2.27E+06 - - - -0.0841 - 2.456 0.543 - 245.4 1 2 0 -0.0001 16 0 0 0 - - - - - 6.8994 1 221125_WJC_METTL3_EV_vs_WT_F04.20881.20881.3 6.10E-07 16/60 K.K[136.11]PELVISYLPPGMASK[136.11].L "sp|P78347|GTF2I_HUMAN,tr|A0A494C1K3|A0A494C1K3_HUMAN" 2 1744.9768 1.58 53957 20881 3 1744.974974 582.6662 General transcription factor II-I OS=Homo sapiens OX=9606 GN=GTF2I PE=1 SV=2 8.5 3393.9 - 1.25E+06 - - - -1.0631 - 3.219 0.499 - 317.3 1 2 0 -0.0019 16 0 0 0 1.15E+08 7.29E+07 - - - 7.1025 0.9999 221125_WJC_METTL3_EV_vs_WT_F04.20883.20883.3 0.000113 16/56 R.QYYTLLNQAPDMLHR[166.11].F "sp|Q13283|G3BP1_HUMAN,tr|E5RH00|E5RH00_HUMAN,tr|E5RH42|E5RH42_HUMAN,tr|A0A7I2V4Y8|A0A7I2V4Y8_HUMAN,tr|A0A7I2V3C4|A0A7I2V3C4_HUMAN,tr|A0A7P0P2U7|A0A7P0P2U7_HUMAN,tr|A0A7I2V2S5|A0A7I2V2S5_HUMAN,tr|A0A7I2YQU8|A0A7I2YQU8_HUMAN,tr|E5RJU8|E5RJU8_HUMAN,tr|A0A7I2V651|A0A7I2V651_HUMAN,tr|E5RIF8|E5RIF8_HUMAN,tr|A0A7I2YQN9|A0A7I2YQN9_HUMAN" 12 1871.9228 1 53959 20883 3 1871.91883 624.9815 Ras GTPase-activating protein-binding protein 1 OS=Homo sapiens OX=9606 GN=G3BP1 PE=1 SV=1 6.74 3394.1 - 1.60E+06 - - - -2.1064 - 2.569 0.447 - 308.1 1 2 0 -0.0039 15 0 0 0 7.98E+07 8.01E+07 - - - 5.9845 1 221125_WJC_METTL3_EV_vs_WT_F04.20884.20884.3 5.55E-07 15/48 R.C[160.03]HIDLSGIVEEVK.A sp|Q6KB66|K2C80_HUMAN 1 1497.7497 9.24 53960 20884 3 1497.749431 500.2572 "Keratin, type II cytoskeletal 80 OS=Homo sapiens OX=9606 GN=KRT80 PE=1 SV=2" 4.65 3394.3 - 1.32E+06 - - - -0.1996 - 2.393 0.532 - 301.4 1 2 0 -0.0003 13 0 0 0 5.50E+07 5.95E+06 - - - 6.8369 0.9999 221125_WJC_METTL3_EV_vs_WT_F04.20889.20889.2 1.97E-06 13/28 K.NAVITVPAYFNDSQR.Q "sp|P38646|GRP75_HUMAN,sp|P0DMV8|HS71A_HUMAN,sp|P34931|HS71L_HUMAN,sp|P0DMV9|HS71B_HUMAN,tr|H0Y8K0|H0Y8K0_HUMAN,tr|A0A7I2V2S7|A0A7I2V2S7_HUMAN,tr|A0A7I2V2G2|A0A7I2V2G2_HUMAN,tr|Q53FA3|Q53FA3_HUMAN,tr|A0A7I2V3F7|A0A7I2V3F7_HUMAN,tr|A0A7I2YQB2|A0A7I2YQB2_HUMAN,tr|A0A0G2JIW1|A0A0G2JIW1_HUMAN,tr|D6RCD7|D6RCD7_HUMAN" 12 1693.8424 0.39 53963 20889 2 1693.840137 847.9285 "Stress-70 protein, mitochondrial OS=Homo sapiens OX=9606 GN=HSPA9 PE=1 SV=2" 5.84 3394.9 - 1.10E+06 - - - -1.3266 - 2.41 0.537 - 297 1 2 0 -0.0022 15 0 0 0 1.33E+08 3.38E+08 - - - 5.1692 1 221125_WJC_METTL3_EV_vs_WT_F04.20895.20895.4 2.88E-07 17/102 K.TVTNAVVTVPAYFNDSQR[166.11].Q "sp|P11142|HSP7C_HUMAN,tr|E9PQQ4|E9PQQ4_HUMAN,tr|E9PN89|E9PN89_HUMAN,tr|E9PLF4|E9PLF4_HUMAN,tr|E9PI65|E9PI65_HUMAN,tr|E9PK54|E9PK54_HUMAN,tr|E9PQK7|E9PQK7_HUMAN" 7 1990.9988 0.11 53965 20895 4 1990.997332 498.757 Heat shock cognate 71 kDa protein OS=Homo sapiens OX=9606 GN=HSPA8 PE=1 SV=1 5.5 3395.7 - 875669 - - - -0.7248 - 3.284 0.593 - 274.4 1 2 0 -0.0014 18 0 0 0 2.61E+06 2.42E+07 - - - 4.7944 0.9918 221125_WJC_METTL3_EV_vs_WT_F04.20902.20902.2 7.20E-05 16-Oct V.PAYFNDSQR.Q "sp|P38646|GRP75_HUMAN,sp|P54652|HSP72_HUMAN,sp|P0DMV8|HS71A_HUMAN,sp|P34931|HS71L_HUMAN,sp|P11142|HSP7C_HUMAN,sp|P0DMV9|HS71B_HUMAN,sp|P17066|HSP76_HUMAN,tr|E9PQQ4|E9PQQ4_HUMAN,tr|H0Y8K0|H0Y8K0_HUMAN,tr|E9PN89|E9PN89_HUMAN,tr|A0A7I2V2S7|A0A7I2V2S7_HUMAN,tr|A0A7I2V2G2|A0A7I2V2G2_HUMAN,tr|E9PLF4|E9PLF4_HUMAN,tr|Q53FA3|Q53FA3_HUMAN,tr|E9PI65|E9PI65_HUMAN,tr|E9PK54|E9PK54_HUMAN,tr|A0A7I2V3F7|A0A7I2V3F7_HUMAN,tr|A0A7I2YQB2|A0A7I2YQB2_HUMAN,tr|E9PQK7|E9PQK7_HUMAN,tr|A0A0G2JIW1|A0A0G2JIW1_HUMAN,tr|D6RCD7|D6RCD7_HUMAN" 21 1096.4938 0.17 53969 20902 2 1096.492336 549.2542 "Stress-70 protein, mitochondrial OS=Homo sapiens OX=9606 GN=HSPA9 PE=1 SV=2" 6.26 3396.5 - 600475 - - - -1.3096 - 2.077 0.554 - 456.8 1 1 0 -0.0014 9 0 0 0 3.15E+07 1.82E+08 - - - 5.247 1 221125_WJC_METTL3_EV_vs_WT_F04.20907.20907.2 4.47E-12 16/30 Y.SDNQPGVLIQVYEGER[166.11].A "sp|P0DMV8|HS71A_HUMAN,sp|P34931|HS71L_HUMAN,sp|P11142|HSP7C_HUMAN,sp|P0DMV9|HS71B_HUMAN,tr|E9PNE6|E9PNE6_HUMAN,tr|A8K7Q2|A8K7Q2_HUMAN,tr|E9PKE3|E9PKE3_HUMAN,tr|E9PS65|E9PS65_HUMAN,tr|Q53FA3|Q53FA3_HUMAN,tr|V9GZ37|V9GZ37_HUMAN,tr|A0A0G2JIW1|A0A0G2JIW1_HUMAN" 11 1812.8882 0.16 53972 20907 2 1812.881687 907.4514 Heat shock 70 kDa protein 1A OS=Homo sapiens OX=9606 GN=HSPA1A PE=1 SV=1 4.14 3397.1 - 1.33E+06 - - - -3.5716 - 3.294 0.71 - 725.8 1 1 0 -0.0065 16 0 0 0 5.23E+07 3.35E+08 - - - 7.2139 1 221125_WJC_METTL3_EV_vs_WT_F04.20909.20909.3 7.65E-09 16/40 R.TQDEC[160.03]ILHFLR.L "sp|Q8TAQ2|SMRC2_HUMAN,sp|Q92922|SMRC1_HUMAN,tr|F8VXC8|F8VXC8_HUMAN" 3 1430.6976 2.65 53974 20909 3 1430.696561 477.9065 SWI\SNF complex subunit SMARCC2 OS=Homo sapiens OX=9606 GN=SMARCC2 PE=1 SV=1 5.29 3397.4 - 1.07E+06 - - - -0.75 - 3.077 0.594 - 641.9 1 2 0 -0.0011 11 0 0 0 4.90E+07 1.85E+07 - - - 8.3552 0.7932 221125_WJC_METTL3_EV_vs_WT_F04.20912.20912.3 0.183 Nov-56 K.SVTDSIRDEYAFLQK.K "sp|O00429|DNM1L_HUMAN,tr|F8VZ52|F8VZ52_HUMAN" 2 1770.8788 0.63 53975 20912 3 1770.875814 591.3002 Dynamin-1-like protein OS=Homo sapiens OX=9606 GN=DNM1L PE=1 SV=2 4.56 3397.8 - 1.89E+06 - - - -1.7025 - 1.492 0.13 - 77.8 1 2 1 -0.003 15 0 0 0 2.77E+07 4.43E+07 - - - 1.0326 0.9984 221125_WJC_METTL3_EV_vs_WT_F04.20914.20914.3 4.10E-09 15/60 Y.SDNQPGVLIQVYEGER[166.11].A "sp|P0DMV8|HS71A_HUMAN,sp|P34931|HS71L_HUMAN,sp|P11142|HSP7C_HUMAN,sp|P0DMV9|HS71B_HUMAN,tr|E9PNE6|E9PNE6_HUMAN,tr|A8K7Q2|A8K7Q2_HUMAN,tr|E9PKE3|E9PKE3_HUMAN,tr|E9PS65|E9PS65_HUMAN,tr|Q53FA3|Q53FA3_HUMAN,tr|V9GZ37|V9GZ37_HUMAN,tr|A0A0G2JIW1|A0A0G2JIW1_HUMAN" 11 1812.8882 0.18 53977 20914 3 1812.889569 605.3033 Heat shock 70 kDa protein 1A OS=Homo sapiens OX=9606 GN=HSPA1A PE=1 SV=1 4.14 3397.9 - 2.91E+06 - - - 0.7761 - 2.97 0.556 - 366.1 1 1 0 0.0014 16 0 0 0 6.90E+07 3.79E+08 - - - 7.5316 0.9999 221125_WJC_METTL3_EV_vs_WT_F04.20916.20916.3 4.58E-05 Nov-48 R.GHTAEILDFALSK[136.11].D "sp|Q13685|AAMP_HUMAN,tr|H7C0R2|H7C0R2_HUMAN,tr|C9JG97|C9JG97_HUMAN,tr|C9JEH3|C9JEH3_HUMAN" 4 1408.7442 1.34 53979 20916 3 1408.744479 470.5887 Angio-associated migratory cell protein OS=Homo sapiens OX=9606 GN=AAMP PE=1 SV=2 5.32 3398.2 - 543148 - - - 0.2122 - 2.208 0.452 - 185.7 1 2 0 0.0003 13 0 0 0 9.82E+06 7.31E+06 - - - 5.7268 0.9999 221125_WJC_METTL3_EV_vs_WT_F04.20919.20919.3 3.38E-05 13/56 K.NAVITVPAYFNDSQR.Q "sp|P38646|GRP75_HUMAN,sp|P0DMV8|HS71A_HUMAN,sp|P34931|HS71L_HUMAN,sp|P0DMV9|HS71B_HUMAN,tr|H0Y8K0|H0Y8K0_HUMAN,tr|A0A7I2V2S7|A0A7I2V2S7_HUMAN,tr|A0A7I2V2G2|A0A7I2V2G2_HUMAN,tr|Q53FA3|Q53FA3_HUMAN,tr|A0A7I2V3F7|A0A7I2V3F7_HUMAN,tr|A0A7I2YQB2|A0A7I2YQB2_HUMAN,tr|A0A0G2JIW1|A0A0G2JIW1_HUMAN,tr|D6RCD7|D6RCD7_HUMAN" 12 1693.8424 0.09 53980 20919 3 1693.845609 565.6214 "Stress-70 protein, mitochondrial OS=Homo sapiens OX=9606 GN=HSPA9 PE=1 SV=2" 5.84 3398.6 - 887446 - - - 1.904 - 2.34 0.415 - 205.1 1 2 0 0.0032 15 0 0 0 2.43E+07 2.67E+08 - - - 5.3843 0.9999 221125_WJC_METTL3_EV_vs_WT_F04.20920.20920.3 8.14E-05 Dec-48 R.GHTAEILDFALSK.D "sp|Q13685|AAMP_HUMAN,tr|H7C0R2|H7C0R2_HUMAN,tr|C9JG97|C9JG97_HUMAN,tr|C9JEH3|C9JEH3_HUMAN" 4 1400.73 1.34 53981 20920 3 1400.729518 467.9173 Angio-associated migratory cell protein OS=Homo sapiens OX=9606 GN=AAMP PE=1 SV=2 5.32 3398.7 - 800185 - - - -0.3298 - 2.165 0.401 - 318.1 1 2 0 -0.0005 13 0 0 0 9.82E+06 7.31E+06 - - - 5.1049 1 221125_WJC_METTL3_EV_vs_WT_F04.20922.20922.3 1.47E-06 15/40 R.TQDEC[160.03]ILHFLR[166.11].L "sp|Q8TAQ2|SMRC2_HUMAN,sp|Q92922|SMRC1_HUMAN,tr|F8VXC8|F8VXC8_HUMAN" 3 1440.7059 2.64 53983 20922 3 1440.706524 481.2426 SWI\SNF complex subunit SMARCC2 OS=Homo sapiens OX=9606 GN=SMARCC2 PE=1 SV=1 5.29 3399 - 1.08E+06 - - - 0.4303 - 2.824 0.563 - 543.5 1 2 0 0.0006 11 0 0 0 4.90E+07 1.85E+07 - - - 7.7659 0.9999 221125_WJC_METTL3_EV_vs_WT_F04.20931.20931.3 9.31E-06 14/56 R.IDDLQMVLNQTEDHR[166.11].Q "sp|Q93050|VPP1_HUMAN,tr|B7Z2A9|B7Z2A9_HUMAN,tr|B7Z641|B7Z641_HUMAN" 3 1835.8711 1.29 53990 20931 3 1835.874119 612.9643 V-type proton ATPase 116 kDa subunit a1 OS=Homo sapiens OX=9606 GN=ATP6V0A1 PE=1 SV=3 4.22 3400.1 - 792661 - - - 1.627 - 2.44 0.464 - 269.4 1 2 0 0.003 15 0 0 0 2.84E+07 2.20E+07 - - - 6.0399 1 221125_WJC_METTL3_EV_vs_WT_F04.20937.20937.3 2.40E-12 24/76 R.IIDDSEITK[136.11]EDDALWPPPDR[166.11].V "sp|Q96A72|MGN2_HUMAN,sp|P61326|MGN_HUMAN,tr|F5H6N1|F5H6N1_HUMAN,tr|F5H3U9|F5H3U9_HUMAN,tr|F5H6P7|F5H6P7_HUMAN" 5 2342.1397 2.38 53994 20937 3 2342.137605 781.7205 Protein mago nashi homolog 2 OS=Homo sapiens OX=9606 GN=MAGOHB PE=1 SV=1 3.85 3400.9 - 2.37E+06 - - - -0.8911 - 4.045 0.674 - 361.8 1 2 1 -0.0021 20 0 0 0 1.31E+08 5.50E+07 - - - 9.4442 0.9963 221125_WJC_METTL3_EV_vs_WT_F04.20939.20939.4 0.0369 16/114 R.FVHSENQHLVSPEALDFLDK.L "sp|P68400|CSK21_HUMAN,sp|Q8NEV1|CSK23_HUMAN,tr|A0A2R8YFU2|A0A2R8YFU2_HUMAN,tr|A0A2R8YD58|A0A2R8YD58_HUMAN,tr|A0A2R8YF43|A0A2R8YF43_HUMAN,tr|A0A2R8Y5A0|A0A2R8Y5A0_HUMAN,tr|A0A087WY74|A0A087WY74_HUMAN,tr|A0A2R8YDP2|A0A2R8YDP2_HUMAN,tr|E7EU96|E7EU96_HUMAN" 9 2324.1437 1.75 53996 20939 4 2324.14354 582.0432 Casein kinase II subunit alpha OS=Homo sapiens OX=9606 GN=CSNK2A1 PE=1 SV=1 4.72 3401.2 - 1.59E+06 - - - -0.0736 - 2.768 0.226 - 93 1 2 0 -0.0002 20 0 0 0 2.37E+07 1.35E+07 - - - 1.5334 1 221125_WJC_METTL3_EV_vs_WT_F04.20940.20940.4 1.44E-07 22/138 R.FSTFAGSITGPLYTHRPPITISSK.L "sp|P07197|NFM_HUMAN,tr|E7ESP9|E7ESP9_HUMAN,tr|E7EMV2|E7EMV2_HUMAN" 3 2577.3591 3.4 53997 20940 4 2577.3586 645.3471 Neurofilament medium polypeptide OS=Homo sapiens OX=9606 GN=NEFM PE=1 SV=3 9.99 3401.3 - 1.49E+06 - - - -0.2033 - 4.117 0.534 - 332.6 1 2 0 -0.0005 24 0 0 0 5.90E+07 1.74E+07 - - - 4.328 0.9989 221125_WJC_METTL3_EV_vs_WT_F04.20945.20945.3 0.00745 15/48 K.QLDDLK[136.11]VELSQLR[166.11].V "sp|P42766|RL35_HUMAN,tr|F2Z388|F2Z388_HUMAN" 2 1573.8794 0.55 54002 20945 3 1573.875535 525.6338 60S ribosomal protein L35 OS=Homo sapiens OX=9606 GN=RPL35 PE=1 SV=2 4.56 3402 - 703158 - - - -2.4824 - 2.176 0.417 - 320.1 1 2 1 -0.0039 13 0 0 0 1.07E+07 1.97E+07 - - - 5.2961 0.9982 221125_WJC_METTL3_EV_vs_WT_F04.20946.20946.3 3.60E-09 18/100 R.TNALTVQQLTAAQQQQYALAAAQQPH.L "sp|Q8TB72|PUM2_HUMAN,tr|A0A0C4DG68|A0A0C4DG68_HUMAN,tr|C9JW01|C9JW01_HUMAN" 3 2792.4206 - 54003 20946 3 2792.423283 931.8141 Pumilio homolog 2 OS=Homo sapiens OX=9606 GN=PUM2 PE=1 SV=2 6.4 3402.1 - 684943 - - - 0.9769 - 3.129 0.562 - 236.3 1 1 0 0.0027 26 0 0 0 - - - - - 7.4294 0.9819 221125_WJC_METTL3_EV_vs_WT_F04.20948.20948.2 0.00037 30-Dec Y.NYGNEDQAEFLC[160.03]VVSK[136.11].E sp|Q9NXV2|KCTD5_HUMAN 1 1879.8502 8.16 54005 20948 2 1879.845122 940.9324 BTB\POZ domain-containing protein KCTD5 OS=Homo sapiens OX=9606 GN=KCTD5 PE=1 SV=1 4.14 3402.4 - 385271 - - - -2.6896 - 2.527 0.575 - 212.2 1 1 0 -0.0051 16 0 0 0 1.96E+07 2.40E+06 - - - 5.5655 1 221125_WJC_METTL3_EV_vs_WT_F04.20952.20952.3 5.99E-12 24/76 R.IIDDSEITKEDDALWPPPDR.V "sp|Q96A72|MGN2_HUMAN,sp|P61326|MGN_HUMAN,tr|F5H6N1|F5H6N1_HUMAN,tr|F5H3U9|F5H3U9_HUMAN,tr|F5H6P7|F5H6P7_HUMAN" 5 2324.1172 2.4 54007 20952 3 2324.116754 775.713 Protein mago nashi homolog 2 OS=Homo sapiens OX=9606 GN=MAGOHB PE=1 SV=1 3.85 3402.8 - 7.01E+06 - - - -0.2014 - 4.123 0.63 - 365.9 1 2 1 -0.0005 20 0 0 0 1.32E+08 5.50E+07 - - - 9.0004 0.9971 221125_WJC_METTL3_EV_vs_WT_F04.20954.20954.3 8.27E-06 16/72 K.ISSIQSIVPALEIANAHRK.P "sp|P10809|CH60_HUMAN,tr|A0A7I2V2X6|A0A7I2V2X6_HUMAN,tr|A0A7I2YQK6|A0A7I2YQK6_HUMAN,tr|A0A7I2V599|A0A7I2V599_HUMAN,tr|A0A7I2YQ71|A0A7I2YQ71_HUMAN,tr|A0A7I2V5M1|A0A7I2V5M1_HUMAN,tr|A0A7I2V5K3|A0A7I2V5K3_HUMAN,tr|A0A7I2V369|A0A7I2V369_HUMAN" 8 2046.1586 1.07 54009 20954 3 2046.157326 683.0601 "60 kDa heat shock protein, mitochondrial OS=Homo sapiens OX=9606 GN=HSPD1 PE=1 SV=2" 8.75 3402.9 - 6.36E+06 - - - -0.6094 - 2.742 0.5 - 188.5 1 1 0 -0.0012 19 0 0 0 2.17E+08 2.03E+08 - - - 6.5923 0.9997 221125_WJC_METTL3_EV_vs_WT_F04.20956.20956.2 3.67E-05 24-Dec K.DTNGSQFFITTVK.T "sp|P23284|PPIB_HUMAN,tr|A0A7P0Z497|A0A7P0Z497_HUMAN,tr|A0A7P0TB45|A0A7P0TB45_HUMAN" 3 1456.7198 0.34 54011 20956 2 1456.721402 729.3672 Peptidyl-prolyl cis-trans isomerase B OS=Homo sapiens OX=9606 GN=PPIB PE=1 SV=2 5.84 3403.1 - 299440 - - - 1.0936 - 2.135 0.396 - 415.5 1 2 0 0.0016 13 0 0 0 4.04E+06 1.18E+07 - - - 3.912 1 221125_WJC_METTL3_EV_vs_WT_F04.20958.20958.3 5.35E-08 16/68 K.TVTNAVVTVPAYFNDSQR[166.11].Q "sp|P11142|HSP7C_HUMAN,tr|E9PQQ4|E9PQQ4_HUMAN,tr|E9PN89|E9PN89_HUMAN,tr|E9PLF4|E9PLF4_HUMAN,tr|E9PI65|E9PI65_HUMAN,tr|E9PK54|E9PK54_HUMAN,tr|E9PQK7|E9PQK7_HUMAN" 7 1990.9988 0.16 54012 20958 3 1990.997786 664.6735 Heat shock cognate 71 kDa protein OS=Homo sapiens OX=9606 GN=HSPA8 PE=1 SV=1 5.5 3403.3 - 1.27E+08 - - - -0.4967 - 3.152 0.597 - 364.4 1 2 0 -0.001 18 0 0 0 2.57E+09 1.57E+10 - - - 8.0544 0.9998 221125_WJC_METTL3_EV_vs_WT_F04.20960.20960.2 0.00353 16-Oct R.YLDVSILGK[136.11].F sp|Q86U44|MTA70_HUMAN 1 1014.5841 0.02 54013 20960 2 1014.583325 508.2993 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 5.83 3403.5 - 6.17E+06 - - - -0.7619 - 1.831 0.444 - 237.1 1 2 0 -0.0008 9 0 0 0 3.96E+06 2.02E+08 - - - 4.07 1 221125_WJC_METTL3_EV_vs_WT_F04.20961.20961.3 4.34E-08 18/104 R.TLYDAELSQMQSHISDTSVVLSMDNNR.S sp|P12035|K2C3_HUMAN 1 3053.407 999 54014 20961 3 3053.40426 1018.8096 "Keratin, type II cytoskeletal 3 OS=Homo sapiens OX=9606 GN=KRT3 PE=1 SV=3" 4.22 3403.7 - 2.82E+06 - - - -0.9023 - 3.011 0.526 - 279.2 1 2 0 -0.0028 27 0 0 0 7.07E+07 0.00E+00 - - - 6.9395 1 221125_WJC_METTL3_EV_vs_WT_F04.20965.20965.2 2.60E-11 17/30 R.DWSNGAVLQASSQLSR.G sp|Q86YP4|P66A_HUMAN 1 1717.8384 1.36 54016 20965 2 1717.837695 859.9265 Transcriptional repressor p66-alpha OS=Homo sapiens OX=9606 GN=GATAD2A PE=1 SV=1 5.84 3404.2 - 1.04E+06 - - - -0.3877 - 3.622 0.682 - 848.9 1 2 0 -0.0007 16 0 0 0 1.62E+07 1.19E+07 - - - 7.2423 0.9989 221125_WJC_METTL3_EV_vs_WT_F04.20966.20966.3 0.00158 Nov-48 K.QLDDLKVELSQLR.V "sp|P42766|RL35_HUMAN,tr|F2Z388|F2Z388_HUMAN" 2 1555.857 0.55 54017 20966 3 1555.856618 519.6263 60S ribosomal protein L35 OS=Homo sapiens OX=9606 GN=RPL35 PE=1 SV=2 4.56 3404.3 - 1.04E+06 - - - -0.2275 - 1.984 0.36 - 159.2 1 2 1 -0.0004 13 0 0 0 1.07E+07 1.97E+07 - - - 4.4111 1 221125_WJC_METTL3_EV_vs_WT_F04.20967.20967.2 2.77E-12 16/30 Y.SDNQPGVLIQVYEGER.A "sp|P0DMV8|HS71A_HUMAN,sp|P34931|HS71L_HUMAN,sp|P11142|HSP7C_HUMAN,sp|P0DMV9|HS71B_HUMAN,tr|E9PNE6|E9PNE6_HUMAN,tr|A8K7Q2|A8K7Q2_HUMAN,tr|E9PKE3|E9PKE3_HUMAN,tr|E9PS65|E9PS65_HUMAN,tr|Q53FA3|Q53FA3_HUMAN,tr|V9GZ37|V9GZ37_HUMAN,tr|A0A0G2JIW1|A0A0G2JIW1_HUMAN" 11 1802.8799 0.12 54018 20967 2 1802.879999 902.4472 Heat shock 70 kDa protein 1A OS=Homo sapiens OX=9606 GN=HSPA1A PE=1 SV=1 4.14 3404.4 - 2.45E+06 - - - 0.0593 - 3.042 0.66 - 675.6 1 1 0 0.0001 16 0 0 0 2.29E+07 1.86E+08 - - - 6.6509 1 221125_WJC_METTL3_EV_vs_WT_F04.20971.20971.3 3.03E-06 18/72 R.DQPAFTPSGILTPHALGSR[166.11].N sp|Q9H0D6|XRN2_HUMAN 1 1974.0198 1.07 54022 20971 3 1974.020195 659.0139 5'-3' exoribonuclease 2 OS=Homo sapiens OX=9606 GN=XRN2 PE=1 SV=1 6.74 3404.7 - 1.03E+06 - - - 0.1773 - 3.257 0.587 - 403.7 1 2 0 0.0004 19 0 0 0 4.43E+07 4.13E+07 - - - 7.9854 1 221125_WJC_METTL3_EV_vs_WT_F04.20980.20980.2 7.24E-09 19/34 K.TVTNAVVTVPAYFNDSQR[166.11].Q "sp|P11142|HSP7C_HUMAN,tr|E9PQQ4|E9PQQ4_HUMAN,tr|E9PN89|E9PN89_HUMAN,tr|E9PLF4|E9PLF4_HUMAN,tr|E9PI65|E9PI65_HUMAN,tr|E9PK54|E9PK54_HUMAN,tr|E9PQK7|E9PQK7_HUMAN" 7 1990.9988 0.16 54030 20980 2 1990.998375 996.5067 Heat shock cognate 71 kDa protein OS=Homo sapiens OX=9606 GN=HSPA8 PE=1 SV=1 5.5 3405.9 - 1.15E+07 - - - -0.2009 - 3.347 0.632 - 718.8 1 2 0 -0.0004 18 0 0 0 1.16E+09 7.18E+09 - - - 6.6789 1 221125_WJC_METTL3_EV_vs_WT_F04.20981.20981.3 2.57E-09 14/60 Y.SDNQPGVLIQVYEGER.A "sp|P0DMV8|HS71A_HUMAN,sp|P34931|HS71L_HUMAN,sp|P11142|HSP7C_HUMAN,sp|P0DMV9|HS71B_HUMAN,tr|E9PNE6|E9PNE6_HUMAN,tr|A8K7Q2|A8K7Q2_HUMAN,tr|E9PKE3|E9PKE3_HUMAN,tr|E9PS65|E9PS65_HUMAN,tr|Q53FA3|Q53FA3_HUMAN,tr|V9GZ37|V9GZ37_HUMAN,tr|A0A0G2JIW1|A0A0G2JIW1_HUMAN" 11 1802.8799 0.16 54031 20981 3 1802.881215 601.9672 Heat shock 70 kDa protein 1A OS=Homo sapiens OX=9606 GN=HSPA1A PE=1 SV=1 4.14 3405.9 - 2.97E+06 - - - 0.7338 - 2.811 0.658 - 295.9 1 1 0 0.0013 16 0 0 0 5.82E+07 3.72E+08 - - - 8.5276 1 221125_WJC_METTL3_EV_vs_WT_F04.20982.20982.3 4.36E-08 13/56 R.GFAFVTFDDHDSVDK.L "sp|Q32P51|RA1L2_HUMAN,sp|P09651|ROA1_HUMAN,tr|A0A7I2YQX9|A0A7I2YQX9_HUMAN,tr|F8VZ49|F8VZ49_HUMAN,tr|A0A7I2V3R8|A0A7I2V3R8_HUMAN,tr|F8VTQ5|F8VTQ5_HUMAN,tr|F8W6I7|F8W6I7_HUMAN,tr|H0YH80|H0YH80_HUMAN,tr|A0A7I2V2L6|A0A7I2V2L6_HUMAN,tr|A0A7I2V3W0|A0A7I2V3W0_HUMAN,tr|A0A7I2V5U9|A0A7I2V5U9_HUMAN,tr|A0A2R8Y4L2|A0A2R8Y4L2_HUMAN" 12 1698.7526 1.29 54032 20982 3 1698.754605 567.2581 Heterogeneous nuclear ribonucleoprotein A1-like 2 OS=Homo sapiens OX=9606 GN=HNRNPA1L2 PE=2 SV=2 4.13 3406 - 3.78E+06 - - - 1.2003 - 2.904 0.537 - 130.1 1 2 0 0.002 15 0 0 0 2.33E+08 1.81E+08 - - - 7.3083 1 221125_WJC_METTL3_EV_vs_WT_F04.20983.20983.3 3.65E-08 13/56 R.GFAFVTFDDHDSVDK[136.11].L "sp|Q32P51|RA1L2_HUMAN,sp|P09651|ROA1_HUMAN,tr|A0A7I2YQX9|A0A7I2YQX9_HUMAN,tr|F8VZ49|F8VZ49_HUMAN,tr|A0A7I2V3R8|A0A7I2V3R8_HUMAN,tr|F8VTQ5|F8VTQ5_HUMAN,tr|F8W6I7|F8W6I7_HUMAN,tr|H0YH80|H0YH80_HUMAN,tr|A0A7I2V2L6|A0A7I2V2L6_HUMAN,tr|A0A7I2V3W0|A0A7I2V3W0_HUMAN,tr|A0A7I2V5U9|A0A7I2V5U9_HUMAN,tr|A0A2R8Y4L2|A0A2R8Y4L2_HUMAN" 12 1706.7668 1.29 54033 20983 3 1706.76896 569.9295 Heterogeneous nuclear ribonucleoprotein A1-like 2 OS=Homo sapiens OX=9606 GN=HNRNPA1L2 PE=2 SV=2 4.13 3406 - 3.39E+06 - - - 1.2855 - 2.54 0.551 - 105.2 1 2 0 0.0022 15 0 0 0 2.33E+08 1.81E+08 - - - 7.1149 1 221125_WJC_METTL3_EV_vs_WT_F04.20985.20985.3 1.07E-06 26/92 R.ISTSPSVALSKPYMTVSSEFPAAR.L "sp|Q6W2J9|BCOR_HUMAN,tr|H7BZ37|H7BZ37_HUMAN,tr|H7C2V9|H7C2V9_HUMAN,tr|H7BYY2|H7BYY2_HUMAN,tr|H7C231|H7C231_HUMAN" 5 2525.2836 1.6 54035 20985 3 2525.285848 842.7685 BCL-6 corepressor OS=Homo sapiens OX=9606 GN=BCOR PE=1 SV=1 8.59 3406.2 - 1.20E+06 - - - 0.8997 - 4.232 0.605 - 566.8 1 2 0 0.0023 24 0 0 0 2.46E+07 1.54E+07 - - - 8.6353 0.9999 221125_WJC_METTL3_EV_vs_WT_F04.21000.21000.3 1.59E-07 22/64 K.LGVQVVITDPEK[136.11]LDQIR[166.11].Q "sp|P17987|TCPA_HUMAN,tr|F5GZ03|F5GZ03_HUMAN,tr|F5H282|F5H282_HUMAN,tr|E7EQR6|E7EQR6_HUMAN,tr|E7ERF2|E7ERF2_HUMAN" 5 1940.1061 0.43 54048 21000 3 1940.108196 647.7093 T-complex protein 1 subunit alpha OS=Homo sapiens OX=9606 GN=TCP1 PE=1 SV=1 4.56 3408.1 - 1.23E+06 - - - 1.0561 - 3.676 0.551 - 762.4 1 2 1 0.002 17 0 0 0 6.64E+06 1.56E+07 - - - 7.9713 0.9999 221125_WJC_METTL3_EV_vs_WT_F04.21001.21001.3 3.35E-05 Nov-76 R.GAALDVHESEPFSFAQGPLK[136.11].D sp|P56545|CTBP2_HUMAN 1 2107.0466 1.34 54049 21001 3 2107.048998 703.3561 C-terminal-binding protein 2 OS=Homo sapiens OX=9606 GN=CTBP2 PE=1 SV=1 4.65 3408.2 - 621530 - - - 1.1523 - 2.335 0.447 - 86.5 1 2 0 0.0024 20 0 0 0 1.40E+07 1.05E+07 - - - 5.5802 1 221125_WJC_METTL3_EV_vs_WT_F04.21002.21002.3 1.67E-07 21/100 K.GDPTGAGPEASLEPGADSVSMQAFSR.A sp|P98175|RBM10_HUMAN 1 2533.1391 1.03 54050 21002 3 2533.132553 845.387 RNA-binding protein 10 OS=Homo sapiens OX=9606 GN=RBM10 PE=1 SV=3 3.92 3408.3 - 498282 - - - -2.583 - 3.786 0.621 - 390.3 1 2 0 -0.0065 26 0 0 0 4.84E+06 4.70E+06 - - - 8.5246 0.9997 221125_WJC_METTL3_EV_vs_WT_F04.21004.21004.3 4.33E-05 15/48 R.YEEIVK[136.11]EVSTYIK[136.11].K "sp|P68104|EF1A1_HUMAN,sp|Q5VTE0|EF1A3_HUMAN,tr|A0A7I2V659|A0A7I2V659_HUMAN,tr|A0A7I2V3H3|A0A7I2V3H3_HUMAN,tr|A0A7I2V5N4|A0A7I2V5N4_HUMAN,tr|A0A087WVQ9|A0A087WVQ9_HUMAN,tr|A0A087WV01|A0A087WV01_HUMAN" 7 1615.868 0.34 54052 21004 3 1615.873188 539.6299 Elongation factor 1-alpha 1 OS=Homo sapiens OX=9606 GN=EEF1A1 PE=1 SV=1 4.79 3408.6 - 442807 - - - 3.2168 - 2.822 0.537 - 165.9 1 2 1 0.0052 13 0 0 0 2.40E+06 6.99E+06 - - - 7.3384 0.9999 221125_WJC_METTL3_EV_vs_WT_F04.21005.21005.3 4.68E-05 Nov-60 K.NTSEQDQPMGGWEMIR.K sp|P20700|LMNB1_HUMAN 1 1877.8036 1.91 54053 21005 3 1877.807412 626.9418 Lamin-B1 OS=Homo sapiens OX=9606 GN=LMNB1 PE=1 SV=2 4.14 3408.7 - 391356 - - - 2.013 - 2.148 0.481 - 154 1 2 0 0.0038 16 0 0 0 7.66E+06 4.02E+06 - - - 5.8633 0.9992 221125_WJC_METTL3_EV_vs_WT_F04.21006.21006.4 0.00721 15/90 K.RPPSAFFLFC[160.03]SEYRPK.L "sp|P09429|HMGB1_HUMAN,tr|Q5T7C4|Q5T7C4_HUMAN" 2 2000.9931 0.12 54054 21006 4 2000.999169 501.2555 High mobility group protein B1 OS=Homo sapiens OX=9606 GN=HMGB1 PE=1 SV=3 9.31 3408.9 - 183271 - - - 3.039 - 2.436 0.364 - 204.1 1 2 0 0.0061 16 0 0 0 3.20E+06 2.70E+07 - - - 2.7062 1 221125_WJC_METTL3_EV_vs_WT_F04.21008.21008.2 2.16E-12 16/30 R.DWSNGAVLQASSQLSR[166.11].G sp|Q86YP4|P66A_HUMAN 1 1727.8466 1.36 54055 21008 2 1727.848703 864.9306 Transcriptional repressor p66-alpha OS=Homo sapiens OX=9606 GN=GATAD2A PE=1 SV=1 5.84 3409.1 - 696762 - - - 1.1992 - 3.138 0.69 - 720.7 1 2 0 0.0021 16 0 0 0 1.62E+07 1.19E+07 - - - 6.9482 1 221125_WJC_METTL3_EV_vs_WT_F04.21011.21011.3 2.87E-09 21/72 R.DQPAFTPSGILTPHALGSR.N sp|Q9H0D6|XRN2_HUMAN 1 1964.0116 1.07 54057 21011 3 1964.013324 655.6778 5'-3' exoribonuclease 2 OS=Homo sapiens OX=9606 GN=XRN2 PE=1 SV=1 6.74 3409.3 - 2.15E+06 - - - 0.8905 - 3.354 0.62 - 552.7 1 2 0 0.0017 19 0 0 0 4.43E+07 4.13E+07 - - - 8.425 0.9998 221125_WJC_METTL3_EV_vs_WT_F04.21016.21016.3 1.72E-05 19/64 K.LGVQVVITDPEKLDQIR.Q "sp|P17987|TCPA_HUMAN,tr|F5GZ03|F5GZ03_HUMAN,tr|F5H282|F5H282_HUMAN,tr|E7EQR6|E7EQR6_HUMAN,tr|E7ERF2|E7ERF2_HUMAN" 5 1922.0837 0.43 54062 21016 3 1922.086337 641.7018 T-complex protein 1 subunit alpha OS=Homo sapiens OX=9606 GN=TCP1 PE=1 SV=1 4.56 3409.9 - 769916 - - - 1.3839 - 3.06 0.451 - 347 1 2 1 0.0027 17 0 0 0 6.64E+06 1.56E+07 - - - 6.3929 1 221125_WJC_METTL3_EV_vs_WT_F04.21021.21021.3 5.32E-13 18/76 R.GAALDVHESEPFSFAQGPLK.D sp|P56545|CTBP2_HUMAN 1 2099.0324 0.75 54067 21021 3 2099.036255 700.6847 C-terminal-binding protein 2 OS=Homo sapiens OX=9606 GN=CTBP2 PE=1 SV=1 4.65 3410.5 - 398261 - - - 1.8509 - 3.726 0.639 - 422.4 1 2 0 0.0039 20 0 0 0 2.99E+07 3.96E+07 - - - 8.8542 1 221125_WJC_METTL3_EV_vs_WT_F04.21022.21022.2 1.63E-10 15/30 K.NTSEQDQPMGGWEMIR[166.11].K sp|P20700|LMNB1_HUMAN 1 1887.8119 1.07 54068 21022 2 1887.813306 944.9132 Lamin-B1 OS=Homo sapiens OX=9606 GN=LMNB1 PE=1 SV=2 4.14 3410.6 - 313911 - - - 0.7437 - 3.194 0.69 - 469.7 1 2 0 0.0014 16 0 0 0 8.03E+06 7.52E+06 - - - 6.9919 1 221125_WJC_METTL3_EV_vs_WT_F04.21026.21026.3 1.87E-13 19/60 R.SHFEQWGTLTDC[160.03]VVMR[166.11].D "sp|Q32P51|RA1L2_HUMAN,sp|P09651|ROA1_HUMAN,tr|F8W646|F8W646_HUMAN,tr|F8VZ49|F8VZ49_HUMAN,tr|A0A7I2V3R8|A0A7I2V3R8_HUMAN,tr|F8W6I7|F8W6I7_HUMAN,tr|A0A7I2V2L6|A0A7I2V2L6_HUMAN,tr|A0A7I2V3W0|A0A7I2V3W0_HUMAN" 8 1974.8956 0.94 54070 21026 3 1974.897216 659.3058 Heterogeneous nuclear ribonucleoprotein A1-like 2 OS=Homo sapiens OX=9606 GN=HNRNPA1L2 PE=2 SV=2 5.3 3411.2 - 3.97E+06 - - - 0.8319 - 3.494 0.68 - 722.3 1 2 0 0.0016 16 0 0 0 3.11E+07 3.30E+07 - - - 9.3309 1 221125_WJC_METTL3_EV_vs_WT_F04.21027.21027.2 2.53E-10 15/28 R.GFAFVTFDDHDSVDK.L "sp|Q32P51|RA1L2_HUMAN,sp|P09651|ROA1_HUMAN,tr|A0A7I2YQX9|A0A7I2YQX9_HUMAN,tr|F8VZ49|F8VZ49_HUMAN,tr|A0A7I2V3R8|A0A7I2V3R8_HUMAN,tr|F8VTQ5|F8VTQ5_HUMAN,tr|F8W6I7|F8W6I7_HUMAN,tr|H0YH80|H0YH80_HUMAN,tr|A0A7I2V2L6|A0A7I2V2L6_HUMAN,tr|A0A7I2V3W0|A0A7I2V3W0_HUMAN,tr|A0A7I2V5U9|A0A7I2V5U9_HUMAN,tr|A0A2R8Y4L2|A0A2R8Y4L2_HUMAN" 12 1698.7526 1.15 54071 21027 2 1698.755162 850.3836 Heterogeneous nuclear ribonucleoprotein A1-like 2 OS=Homo sapiens OX=9606 GN=HNRNPA1L2 PE=2 SV=2 4.13 3411.3 - 2.55E+06 - - - 1.5282 - 3.105 0.739 - 671.7 1 2 0 0.0026 15 0 0 0 2.68E+07 2.33E+07 - - - 7.284 1 221125_WJC_METTL3_EV_vs_WT_F04.21028.21028.3 0.0265 18/60 K.R[166.11]PPSAFFLFC[160.03]SEYR[166.11]PK[136.11].L "sp|P09429|HMGB1_HUMAN,tr|Q5T7C4|Q5T7C4_HUMAN" 2 2029.0238 0.05 54072 21028 3 2029.025423 677.3486 High mobility group protein B1 OS=Homo sapiens OX=9606 GN=HMGB1 PE=1 SV=3 9.31 3411.3 - 2.13E+06 - - - 0.7861 - 3.408 0.381 - 565.7 1 2 0 0.0016 16 0 0 0 1.30E+06 2.68E+07 - - - 5.9334 1 221125_WJC_METTL3_EV_vs_WT_F04.21032.21032.3 3.28E-07 23/72 R.ALQAAIQQLAEAQPEATAK.N sp|Q92616|GCN1_HUMAN 1 1951.0375 0.96 54076 21032 3 1951.041844 651.3531 eIF-2-alpha kinase activator GCN1 OS=Homo sapiens OX=9606 GN=GCN1 PE=1 SV=6 4.53 3411.7 - 858492 - - - 2.2496 - 3.886 0.481 - 644.2 1 2 0 0.0044 19 0 0 0 8.77E+06 9.11E+06 - - - 7.2363 1 221125_WJC_METTL3_EV_vs_WT_F04.21034.21034.2 1.94E-08 17/30 K.NTSEQDQPMGGWEMIR.K sp|P20700|LMNB1_HUMAN 1 1877.8036 1.07 54078 21034 2 1877.810842 939.9091 Lamin-B1 OS=Homo sapiens OX=9606 GN=LMNB1 PE=1 SV=2 4.14 3412 - 490958 - - - 3.8396 - 3.563 0.741 - 638 1 2 0 0.0072 16 0 0 0 8.03E+06 7.52E+06 - - - 7.6356 0.8354 221125_WJC_METTL3_EV_vs_WT_F04.21037.21037.3 0.156 Aug-48 R.KTVTAMDVVYALK.R sp|P62805|H4_HUMAN 1 1437.7901 2.61 54081 21037 3 1437.78592 480.2707 Histone H4 OS=Homo sapiens OX=9606 GN=H4C1 PE=1 SV=2 8.5 3412.4 - 301330 - - - -2.9337 - 1.267 0.148 - 58.6 1 2 0 -0.0042 13 0 0 0 5.28E+06 2.02E+06 - - - 0.8305 0.8339 221125_WJC_METTL3_EV_vs_WT_F04.21041.21041.4 0.00349 22/108 K.ISSIQSIVPALEIANAHRK.P "sp|P10809|CH60_HUMAN,tr|A0A7I2V2X6|A0A7I2V2X6_HUMAN,tr|A0A7I2YQK6|A0A7I2YQK6_HUMAN,tr|A0A7I2V599|A0A7I2V599_HUMAN,tr|A0A7I2YQ71|A0A7I2YQ71_HUMAN,tr|A0A7I2V5M1|A0A7I2V5M1_HUMAN,tr|A0A7I2V5K3|A0A7I2V5K3_HUMAN,tr|A0A7I2V369|A0A7I2V369_HUMAN" 8 2046.1586 1.3 54084 21041 4 2046.161457 512.5469 "60 kDa heat shock protein, mitochondrial OS=Homo sapiens OX=9606 GN=HSPD1 PE=1 SV=2" 8.75 3412.9 - 492442 - - - 1.4095 - 3.224 0.26 - 363 1 1 0 0.0029 19 0 0 0 8.31E+08 6.40E+08 - - - 1.8842 1 221125_WJC_METTL3_EV_vs_WT_F04.21043.21043.3 5.31E-10 18/60 R.SHFEQWGTLTDC[160.03]VVMR.D "sp|Q32P51|RA1L2_HUMAN,sp|P09651|ROA1_HUMAN,tr|F8W646|F8W646_HUMAN,tr|F8VZ49|F8VZ49_HUMAN,tr|A0A7I2V3R8|A0A7I2V3R8_HUMAN,tr|F8W6I7|F8W6I7_HUMAN,tr|A0A7I2V2L6|A0A7I2V2L6_HUMAN,tr|A0A7I2V3W0|A0A7I2V3W0_HUMAN" 8 1964.8873 0.94 54085 21043 3 1964.890424 655.9697 Heterogeneous nuclear ribonucleoprotein A1-like 2 OS=Homo sapiens OX=9606 GN=HNRNPA1L2 PE=2 SV=2 5.3 3413.1 - 5.28E+06 - - - 1.5884 - 3.46 0.675 - 618.1 1 2 0 0.0031 16 0 0 0 3.11E+07 3.30E+07 - - - 9.2496 1 221125_WJC_METTL3_EV_vs_WT_F04.21045.21045.2 1.95E-08 13/28 R.GFAFVTFDDHDSVDK[136.11].L "sp|Q32P51|RA1L2_HUMAN,sp|P09651|ROA1_HUMAN,tr|A0A7I2YQX9|A0A7I2YQX9_HUMAN,tr|F8VZ49|F8VZ49_HUMAN,tr|A0A7I2V3R8|A0A7I2V3R8_HUMAN,tr|F8VTQ5|F8VTQ5_HUMAN,tr|F8W6I7|F8W6I7_HUMAN,tr|H0YH80|H0YH80_HUMAN,tr|A0A7I2V2L6|A0A7I2V2L6_HUMAN,tr|A0A7I2V3W0|A0A7I2V3W0_HUMAN,tr|A0A7I2V5U9|A0A7I2V5U9_HUMAN,tr|A0A2R8Y4L2|A0A2R8Y4L2_HUMAN" 12 1706.7668 1.15 54087 21045 2 1706.769606 854.3907 Heterogeneous nuclear ribonucleoprotein A1-like 2 OS=Homo sapiens OX=9606 GN=HNRNPA1L2 PE=2 SV=2 4.13 3413.3 - 1.58E+06 - - - 1.664 - 2.943 0.605 - 427.1 1 2 0 0.0028 15 0 0 0 2.68E+07 2.33E+07 - - - 6.1625 0.9842 221125_WJC_METTL3_EV_vs_WT_F04.21047.21047.3 1.60E-05 Nov-56 R.HMSEFMEC[160.03]NLNELVK[136.11].H "sp|P25786|PSA1_HUMAN,tr|F5GX11|F5GX11_HUMAN" 2 1887.8409 1.17 54089 21047 3 1888.835631 630.2876 Proteasome subunit alpha type-1 OS=Homo sapiens OX=9606 GN=PSMA1 PE=1 SV=1 4.75 3413.4 - 852919 - - - 526.9274 - 2.1 0.517 - 184 1 2 0 0.9948 15 0 0 0 7.22E+06 6.19E+06 - - - 5.9645 1 221125_WJC_METTL3_EV_vs_WT_F04.21048.21048.3 4.55E-10 22/72 R.GQNAC[160.03]SEIYIHGLGLAINR.A "sp|O75817|POP7_HUMAN,tr|C9JYM0|C9JYM0_HUMAN" 2 2085.0426 2.81 54090 21048 3 2085.047866 696.0215 Ribonuclease P protein subunit p20 OS=Homo sapiens OX=9606 GN=POP7 PE=1 SV=2 6.74 3413.6 - 721801 - - - 2.5458 - 3.302 0.569 - 730.9 1 2 0 0.0053 19 0 0 0 6.68E+06 2.38E+06 - - - 7.817 1 221125_WJC_METTL3_EV_vs_WT_F04.21054.21054.4 1.59E-05 15/84 R.KYGEVEEVEILLHPR.T "sp|O15047|SET1A_HUMAN,tr|A0A804HLA6|A0A804HLA6_HUMAN" 2 1809.9625 1.32 54096 21054 4 1809.961632 453.4979 Histone-lysine N-methyltransferase SETD1A OS=Homo sapiens OX=9606 GN=SETD1A PE=1 SV=3 4.91 3414.3 - 165455 - - - -0.479 - 2.932 0.469 - 272 1 2 0 -0.0009 15 0 0 0 2.59E+06 1.96E+06 - - - 3.6928 1 221125_WJC_METTL3_EV_vs_WT_F04.21058.21058.2 1.03E-12 16/28 R.NNQGTVNWSVDDIVK.G "sp|P52292|IMA1_HUMAN,tr|J3QLL0|J3QLL0_HUMAN,tr|J3KS65|J3KS65_HUMAN,tr|A0A7I2V3Z3|A0A7I2V3Z3_HUMAN,tr|A0A7I2YQE1|A0A7I2YQE1_HUMAN,tr|A0A7I2V487|A0A7I2V487_HUMAN,tr|A0A7I2V351|A0A7I2V351_HUMAN" 7 1687.8166 1.17 54098 21058 2 1687.818769 844.9156 Importin subunit alpha-1 OS=Homo sapiens OX=9606 GN=KPNA2 PE=1 SV=1 4.21 3414.9 - 4.40E+06 - - - 1.307 - 3.331 0.653 - 1300.8 1 2 0 0.0022 15 0 0 0 4.03E+07 3.43E+07 - - - 6.8217 0.9962 221125_WJC_METTL3_EV_vs_WT_F04.21059.21059.3 2.65E-05 16/56 K.K[136.11]LLHHLSDLALTLPT.D "sp|Q86U44|MTA70_HUMAN,tr|B4E349|B4E349_HUMAN,tr|F5H6D8|F5H6D8_HUMAN,tr|H0YFV6|H0YFV6_HUMAN,tr|B4DTN4|B4DTN4_HUMAN" 5 1678.9861 0.02 54099 21059 3 1678.989052 560.6693 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 6.92 3414.9 - 2.47E+06 - - - 1.7332 - 2.985 0.497 - 208.3 1 1 0 0.0029 15 0 0 0 9.54E+06 4.16E+08 - - - 6.9339 0.9999 221125_WJC_METTL3_EV_vs_WT_F04.21062.21062.4 3.78E-06 17/90 K.R[166.11]PPSAFFLFC[160.03]SEYR[166.11]PK[136.11].L "sp|P09429|HMGB1_HUMAN,tr|Q5T7C4|Q5T7C4_HUMAN" 2 2029.0238 0.64 54102 21062 4 2029.028389 508.2632 High mobility group protein B1 OS=Homo sapiens OX=9606 GN=HMGB1 PE=1 SV=3 9.31 3415.2 - 1.49E+06 - - - 2.2479 - 2.678 0.477 - 285.7 1 2 0 0.0046 16 0 0 0 2.00E+07 3.11E+07 - - - 3.7235 1 221125_WJC_METTL3_EV_vs_WT_F04.21064.21064.3 2.31E-10 25/72 L.HAYPPQVYGYDDLQMLQTR.F "sp|Q14157|UBP2L_HUMAN,tr|F8W726|F8W726_HUMAN,tr|H7C2T8|H7C2T8_HUMAN,tr|H0Y5H6|H0Y5H6_HUMAN" 4 2294.079 1 54104 21064 3 2294.08059 765.7003 Ubiquitin-associated protein 2-like OS=Homo sapiens OX=9606 GN=UBAP2L PE=1 SV=2 5.21 3415.4 - 1.18E+06 - - - 0.6918 - 5.089 0.687 - 1209.4 1 1 0 0.0016 19 0 0 0 1.19E+07 1.19E+07 - - - 10.1963 0.9664 221125_WJC_METTL3_EV_vs_WT_F04.21065.21065.4 0.00108 13/84 K.K[136.11]LLHHLSDLALTLPT.D "sp|Q86U44|MTA70_HUMAN,tr|B4E349|B4E349_HUMAN,tr|F5H6D8|F5H6D8_HUMAN,tr|H0YFV6|H0YFV6_HUMAN,tr|B4DTN4|B4DTN4_HUMAN" 5 1678.9861 0.01 54105 21065 4 1678.988562 420.7538 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 6.92 3415.6 - 523586 - - - 1.4413 - 2.274 0.363 - 136.3 1 1 0 0.0024 15 0 0 0 5.46E+05 4.93E+07 - - - 2.6788 1 221125_WJC_METTL3_EV_vs_WT_F04.21067.21067.2 3.79E-10 18/38 K.AYLTEENGQIAVFDATNTTR.E sp|O60825|F262_HUMAN 1 2213.06 999 54107 21067 2 2213.062728 1107.5373 "6-phosphofructo-2-kinase\fructose-2,6-bisphosphatase 2 OS=Homo sapiens OX=9606 GN=PFKFB2 PE=1 SV=2" 4.14 3415.8 - 504857 - - - 1.2142 - 3.498 0.655 - 699.1 1 2 0 0.0027 20 0 0 0 3.26E+06 0.00E+00 - - - 6.9566 0.9989 221125_WJC_METTL3_EV_vs_WT_F04.21070.21070.3 0.000942 Nov-40 K.LLDIAC[160.03]WIHHK.Y "sp|P07339|CATD_HUMAN,tr|A0A1B0GW44|A0A1B0GW44_HUMAN,tr|A0A1B0GVD5|A0A1B0GVD5_HUMAN,tr|A0A1B0GV23|A0A1B0GV23_HUMAN,tr|C9JH19|C9JH19_HUMAN,tr|A0A1B0GWE8|A0A1B0GWE8_HUMAN,tr|A0A1B0GU03|A0A1B0GU03_HUMAN,tr|A0A1B0GVP3|A0A1B0GVP3_HUMAN,tr|F8WD96|F8WD96_HUMAN,tr|A0A1B0GU92|A0A1B0GU92_HUMAN,tr|F8W787|F8W787_HUMAN" 11 1404.7336 7.21 54110 21070 3 1404.739084 469.2518 Cathepsin D OS=Homo sapiens OX=9606 GN=CTSD PE=1 SV=1 6.91 3416.2 - 379736 - - - 3.8854 - 2.066 0.377 - 170.1 1 2 0 0.0055 11 0 0 0 3.05E+06 4.23E+05 - - - 4.803 0.9999 221125_WJC_METTL3_EV_vs_WT_F04.21071.21071.3 1.85E-05 13/44 K.GISDLAQHYLMR[166.11].A "sp|P49368|TCPG_HUMAN,tr|B4DUR8|B4DUR8_HUMAN" 2 1412.711 0.16 54111 21071 3 1412.707878 471.9109 T-complex protein 1 subunit gamma OS=Homo sapiens OX=9606 GN=CCT3 PE=1 SV=4 6.74 3416.4 - 362122 - - - -2.2021 - 2.44 0.458 - 184 1 2 0 -0.0031 12 0 0 0 1.16E+06 7.40E+06 - - - 6.1179 1 221125_WJC_METTL3_EV_vs_WT_F04.21072.21072.4 5.66E-07 15/84 R.K[136.11]YGEVEEVEILLHPR[166.11].T "sp|O15047|SET1A_HUMAN,tr|A0A804HLA6|A0A804HLA6_HUMAN" 2 1827.985 1.32 54112 21072 4 1827.987777 458.0035 Histone-lysine N-methyltransferase SETD1A OS=Homo sapiens OX=9606 GN=SETD1A PE=1 SV=3 4.91 3416.5 - 358999 - - - 1.5361 - 2.951 0.55 - 287.7 1 2 0 0.0028 15 0 0 0 2.59E+06 1.96E+06 - - - 4.3996 0.9999 221125_WJC_METTL3_EV_vs_WT_F04.21074.21074.2 2.91E-05 26-Nov K.NEGC[160.03]QVYGFLEVNK.V "sp|Q9Y282|ERGI3_HUMAN,tr|H0Y621|H0Y621_HUMAN,tr|H0Y5K5|H0Y5K5_HUMAN,tr|A0A1W2PPS8|A0A1W2PPS8_HUMAN" 4 1655.7614 2.1 54114 21074 2 1655.761292 828.888 Endoplasmic reticulum-Golgi intermediate compartment protein 3 OS=Homo sapiens OX=9606 GN=ERGIC3 PE=1 SV=1 4.53 3416.7 - 279342 - - - -0.0393 - 2.53 0.529 - 460.1 1 2 0 -0.0001 14 0 0 0 2.85E+06 1.36E+06 - - - 5.2775 1 221125_WJC_METTL3_EV_vs_WT_F04.21078.21078.2 2.62E-13 16/28 R.NNQGTVNWSVDDIVK[136.11].G "sp|P52292|IMA1_HUMAN,tr|J3QLL0|J3QLL0_HUMAN,tr|J3KS65|J3KS65_HUMAN,tr|A0A7I2V3Z3|A0A7I2V3Z3_HUMAN,tr|A0A7I2YQE1|A0A7I2YQE1_HUMAN,tr|A0A7I2V487|A0A7I2V487_HUMAN,tr|A0A7I2V351|A0A7I2V351_HUMAN" 7 1695.8308 1.17 54116 21078 2 1695.830367 848.9227 Importin subunit alpha-1 OS=Homo sapiens OX=9606 GN=KPNA2 PE=1 SV=1 4.21 3417.3 - 3.14E+06 - - - -0.2335 - 3.462 0.695 - 1264.8 1 2 0 -0.0004 15 0 0 0 4.03E+07 3.43E+07 - - - 7.2273 1 221125_WJC_METTL3_EV_vs_WT_F04.21080.21080.3 2.73E-07 21/76 R.VIDFDENTALDDAEEESFR[166.11]K[136.11].L "sp|Q14257|RCN2_HUMAN,tr|H0YL43|H0YL43_HUMAN" 2 2360.0775 0.31 54118 21080 3 2360.078975 787.6998 Reticulocalbin-2 OS=Homo sapiens OX=9606 GN=RCN2 PE=1 SV=1 3.85 3417.4 - 3.42E+06 - - - 0.6313 - 3.617 0.592 - 387.7 1 2 0 0.0015 20 0 0 0 4.71E+06 1.52E+07 - - - 8.2588 1 221125_WJC_METTL3_EV_vs_WT_F04.21082.21082.3 3.93E-07 20/68 K.LQQQQIDIQTHFISAALK.T "sp|Q9BVV6|TALD3_HUMAN,tr|A0A087WYM5|A0A087WYM5_HUMAN,tr|A0A494C0M8|A0A494C0M8_HUMAN,tr|G3V2T5|G3V2T5_HUMAN,tr|A0A494C0Z1|A0A494C0Z1_HUMAN,tr|A0A494C171|A0A494C171_HUMAN" 6 2081.1269 4.99 54120 21082 3 2081.128556 694.7163 Protein TALPID3 OS=Homo sapiens OX=9606 GN=KIAA0586 PE=1 SV=4 6.74 3417.6 - 1.58E+06 - - - 0.777 - 2.988 0.458 - 522.4 1 2 0 0.0016 18 0 0 0 9.71E+06 1.95E+06 - - - 6.3715 1 221125_WJC_METTL3_EV_vs_WT_F04.21084.21084.3 1.09E-07 19/72 R.GLVVLGFPC[160.03]NQFGHQENAK.N sp|P07203|GPX1_HUMAN 1 2114.0367 0.66 54122 21084 3 2114.039531 705.6862 Glutathione peroxidase 1 OS=Homo sapiens OX=9606 GN=GPX1 PE=1 SV=4 6.74 3417.8 - 870603 - - - 1.3183 - 3.137 0.583 - 468.5 1 2 0 0.0028 19 0 0 0 1.36E+07 2.04E+07 - - - 7.8479 1 221125_WJC_METTL3_EV_vs_WT_F04.21085.21085.3 1.89E-08 18/84 K.SISISVAGGGGGFGAAGGFGGR.G sp|P35908|K22E_HUMAN 1 1837.9071 61.65 54123 21085 3 1837.908254 613.643 "Keratin, type II cytoskeletal 2 epidermal OS=Homo sapiens OX=9606 GN=KRT2 PE=1 SV=2" 9.47 3417.9 - 713520 - - - 0.6224 - 3.449 0.54 - 274.8 1 2 0 0.0011 22 0 0 0 2.62E+07 4.25E+05 - - - 7.4954 1 221125_WJC_METTL3_EV_vs_WT_F04.21086.21086.3 0.00582 19/60 R.DLK[136.11]PQNLLINTEGAIK[136.11].L "sp|P24941|CDK2_HUMAN,tr|G3V5T9|G3V5T9_HUMAN,tr|E7ESI2|E7ESI2_HUMAN" 3 1782.0222 0.54 54124 21086 3 1782.020855 595.0147 Cyclin-dependent kinase 2 OS=Homo sapiens OX=9606 GN=CDK2 PE=1 SV=2 6.07 3418 - 711982 - - - -0.7542 - 3.17 0.422 - 471.3 1 2 0 -0.0013 16 0 0 0 4.67E+06 8.61E+06 - - - 6.2048 0.9912 221125_WJC_METTL3_EV_vs_WT_F04.21092.21092.3 8.18E-06 13/64 R.PTDMSALNNLFGPQKPK.V "sp|Q6P3W7|SCYL2_HUMAN,tr|A0A0U1RQQ9|A0A0U1RQQ9_HUMAN" 2 1856.9455 2.37 54130 21092 3 1856.947122 619.9891 SCY1-like protein 2 OS=Homo sapiens OX=9606 GN=SCYL2 PE=1 SV=1 9.01 3418.8 - 383752 - - - 0.8902 - 2.499 0.409 - 177.5 1 1 0 0.0017 17 0 0 0 3.10E+06 1.31E+06 - - - 5.4133 0.9998 221125_WJC_METTL3_EV_vs_WT_F04.21093.21093.3 3.62E-05 Oct-40 R.KEWLTNFMEDR.R "sp|P11388|TOP2A_HUMAN,sp|Q02880|TOP2B_HUMAN,tr|E9PCY5|E9PCY5_HUMAN" 3 1467.6816 0.98 54131 21093 3 1467.686351 490.2345 DNA topoisomerase 2-alpha OS=Homo sapiens OX=9606 GN=TOP2A PE=1 SV=3 4.68 3418.9 - 370793 - - - 3.203 - 2.074 0.486 - 161.1 1 2 0 0.0047 11 0 0 0 2.06E+06 2.10E+06 - - - 6.0294 1 221125_WJC_METTL3_EV_vs_WT_F04.21099.21099.3 1.15E-09 17/56 R.GFAFVTFDDHDTVDK.L "sp|P51991|ROA3_HUMAN,tr|A0A7I2V5D8|A0A7I2V5D8_HUMAN,tr|A0A7I2V2R3|A0A7I2V2R3_HUMAN,tr|A0A7I2V4J6|A0A7I2V4J6_HUMAN,tr|A0A7I2V4G0|A0A7I2V4G0_HUMAN,tr|A0A7I2V402|A0A7I2V402_HUMAN" 6 1712.7682 1.34 54135 21099 3 1712.768373 571.93 Heterogeneous nuclear ribonucleoprotein A3 OS=Homo sapiens OX=9606 GN=HNRNPA3 PE=1 SV=2 4.13 3419.7 - 3.38E+06 - - - 0.0917 - 3.391 0.519 - 253.7 1 2 0 0.0002 15 0 0 0 4.24E+07 3.16E+07 - - - 7.5127 1 221125_WJC_METTL3_EV_vs_WT_F04.21100.21100.3 1.92E-08 14/56 R.GFAFVTFDDHDTVDK[136.11].L "sp|P51991|ROA3_HUMAN,tr|A0A7I2V5D8|A0A7I2V5D8_HUMAN,tr|A0A7I2V2R3|A0A7I2V2R3_HUMAN,tr|A0A7I2V4J6|A0A7I2V4J6_HUMAN,tr|A0A7I2V4G0|A0A7I2V4G0_HUMAN,tr|A0A7I2V402|A0A7I2V402_HUMAN" 6 1720.7824 1.37 54136 21100 3 1720.782227 574.6014 Heterogeneous nuclear ribonucleoprotein A3 OS=Homo sapiens OX=9606 GN=HNRNPA3 PE=1 SV=2 4.13 3419.7 - 2.83E+06 - - - -0.1098 - 3.123 0.645 - 157.3 1 2 0 -0.0002 15 0 0 0 4.34E+07 3.16E+07 - - - 8.7026 1 221125_WJC_METTL3_EV_vs_WT_F04.21103.21103.2 2.08E-13 19/42 K.SISISVAGGGGGFGAAGGFGGR.G sp|P35908|K22E_HUMAN 1 1837.9071 999 54139 21103 2 1837.907738 919.9608 "Keratin, type II cytoskeletal 2 epidermal OS=Homo sapiens OX=9606 GN=KRT2 PE=1 SV=2" 9.47 3420 - 2.19E+06 - - - 0.3417 - 3.5 0.691 - 645.5 1 2 0 0.0006 22 0 0 0 3.14E+07 0.00E+00 - - - 7.2245 0.9935 221125_WJC_METTL3_EV_vs_WT_F04.21105.21105.2 7.26E-07 28-Nov K.K[136.11]LLHHLSDLALTLPT.D "sp|Q86U44|MTA70_HUMAN,tr|B4E349|B4E349_HUMAN,tr|F5H6D8|F5H6D8_HUMAN,tr|H0YFV6|H0YFV6_HUMAN,tr|B4DTN4|B4DTN4_HUMAN" 5 1678.9861 0.001 54141 21105 2 1678.9873 840.5003 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 6.92 3420.2 - 1.80E+06 - - - 0.6897 - 2.294 0.582 - 184.7 1 1 0 0.0012 15 0 0 0 0.00E+00 3.27E+07 - - - 5.3806 1 221125_WJC_METTL3_EV_vs_WT_F04.21107.21107.3 4.78E-10 15/56 R.DEGAVISQISDISNR.D "sp|O75410|TACC1_HUMAN,tr|E7EVI4|E7EVI4_HUMAN,tr|E5RFM9|E5RFM9_HUMAN,tr|A0A0C4DGD5|A0A0C4DGD5_HUMAN,tr|R4GMT7|R4GMT7_HUMAN,tr|H0YAY0|H0YAY0_HUMAN,tr|A0A0C4DGD3|A0A0C4DGD3_HUMAN,tr|H0YBT8|H0YBT8_HUMAN,tr|E7ET87|E7ET87_HUMAN" 9 1602.7849 1.41 54143 21107 3 1602.787606 535.2689 Transforming acidic coiled-coil-containing protein 1 OS=Homo sapiens OX=9606 GN=TACC1 PE=1 SV=2 4.03 3420.4 - 1.33E+06 - - - 1.6702 - 2.96 0.614 - 380.9 1 2 0 0.0027 15 0 0 0 1.55E+07 1.10E+07 - - - 8.2164 1 221125_WJC_METTL3_EV_vs_WT_F04.21109.21109.3 2.25E-07 Dec-48 R.SSHSNAYFYGFFK[136.11].N sp|O75844|FACE1_HUMAN 1 1561.7081 1.07 54145 21109 3 1561.71 521.5767 CAAX prenyl protease 1 homolog OS=Homo sapiens OX=9606 GN=ZMPSTE24 PE=1 SV=2 8.24 3420.6 - 1.32E+06 - - - 1.198 - 2.084 0.628 - 153 1 2 0 0.0019 13 0 0 0 1.24E+07 1.16E+07 - - - 7.5319 1 221125_WJC_METTL3_EV_vs_WT_F04.21110.21110.3 1.83E-07 13/48 R.SSHSNAYFYGFFK.N sp|O75844|FACE1_HUMAN 1 1553.6939 1.09 54146 21110 3 1553.694583 518.9053 CAAX prenyl protease 1 homolog OS=Homo sapiens OX=9606 GN=ZMPSTE24 PE=1 SV=2 8.24 3420.7 - 1.32E+06 - - - 0.4209 - 2.595 0.605 - 178.7 1 2 0 0.0007 13 0 0 0 1.27E+07 1.16E+07 - - - 7.8704 0.9981 221125_WJC_METTL3_EV_vs_WT_F04.21111.21111.3 0.00013 15/72 R.NHTLALTETGSVFAFGENK.M sp|Q9P258|RCC2_HUMAN 1 2035.0011 0.8 54147 21111 3 2036.006583 679.341 Protein RCC2 OS=Homo sapiens OX=9606 GN=RCC2 PE=1 SV=2 5.4 3420.8 - 1.20E+06 - - - 494.1093 - 2.622 0.46 - 287.7 1 2 0 1.0055 19 0 0 0 1.39E+07 1.73E+07 - - - 5.7582 0.9971 221125_WJC_METTL3_EV_vs_WT_F04.21122.21122.3 6.09E-07 19/76 R.QLSEPC[160.03]LYPEPLPALRPTPR.P sp|Q5T749|KPRP_HUMAN 1 2333.2202 999 54156 21122 3 2333.216789 778.7473 Keratinocyte proline-rich protein OS=Homo sapiens OX=9606 GN=KPRP PE=1 SV=1 6.14 3422.1 - 3.10E+06 - - - -1.4568 - 2.649 0.539 - 340.4 1 1 0 -0.0034 20 0 0 0 4.32E+07 0.00E+00 - - - 6.9118 0.9999 221125_WJC_METTL3_EV_vs_WT_F04.21123.21123.3 0.00105 Dec-40 K.QHVTEAFQFHF.- "sp|O43175|SERA_HUMAN,tr|A0A286YF22|A0A286YF22_HUMAN,tr|A0A286YFA2|A0A286YFA2_HUMAN" 3 1389.6466 - 54157 21123 3 1389.646518 464.2228 D-3-phosphoglycerate dehydrogenase OS=Homo sapiens OX=9606 GN=PHGDH PE=1 SV=4 5.98 3422.2 - 2.38E+06 - - - -0.0482 - 2.148 0.426 - 129.8 1 2 0 -0.0001 11 0 0 0 - - - - - 5.4614 0.9984 221125_WJC_METTL3_EV_vs_WT_F04.21126.21126.3 1.26E-08 16/60 V.TNAVITVPAYFNDSQR[166.11].Q "sp|P0DMV8|HS71A_HUMAN,sp|P34931|HS71L_HUMAN,sp|P0DMV9|HS71B_HUMAN,tr|Q53FA3|Q53FA3_HUMAN,tr|A0A0G2JIW1|A0A0G2JIW1_HUMAN" 5 1804.8983 0.1 54160 21126 3 1804.900406 602.6401 Heat shock 70 kDa protein 1A OS=Homo sapiens OX=9606 GN=HSPA1A PE=1 SV=1 5.5 3422.4 - 1.39E+06 - - - 1.1485 - 2.833 0.591 - 426.6 1 1 0 0.0021 16 0 0 0 1.14E+06 1.10E+07 - - - 7.8004 1 221125_WJC_METTL3_EV_vs_WT_F04.21127.21127.3 9.36E-06 17/68 R.GPGGSSLLIEALSNSSHK.C "sp|Q9BSH4|TACO1_HUMAN,tr|A0A804HJB7|A0A804HJB7_HUMAN" 2 1752.9006 1 54161 21127 3 1752.899628 585.3075 Translational activator of cytochrome c oxidase 1 OS=Homo sapiens OX=9606 GN=TACO1 PE=1 SV=1 6.75 3422.5 - 1.22E+06 - - - -0.5699 - 3.541 0.552 - 416.7 1 2 0 -0.001 18 0 0 0 8.57E+06 8.60E+06 - - - 7.8425 1 221125_WJC_METTL3_EV_vs_WT_F04.21130.21130.3 1.54E-13 16/60 K.HVPC[160.03]VEDEDFIQALDK.M sp|Q9HAU5|RENT2_HUMAN 1 1913.8829 1.19 54164 21130 3 1913.887039 638.9683 Regulator of nonsense transcripts 2 OS=Homo sapiens OX=9606 GN=UPF2 PE=1 SV=1 4.1 3422.9 - 543949 - - - 2.1475 - 3.298 0.677 - 455.8 1 2 0 0.0041 16 0 0 0 4.69E+06 3.93E+06 - - - 9.1486 1 221125_WJC_METTL3_EV_vs_WT_F04.21136.21136.3 1.37E-06 18/64 R.AETEC[160.03]QNTEYQQLLDIK.L "sp|P13645|K1C10_HUMAN,tr|A0A1B0GVI3|A0A1B0GVI3_HUMAN" 2 2081.9576 241.73 54168 21136 3 2081.957378 694.9931 "Keratin, type I cytoskeletal 10 OS=Homo sapiens OX=9606 GN=KRT10 PE=1 SV=6" 4 3423.6 - 3.43E+06 - - - -0.0826 - 3.153 0.628 - 442 1 2 0 -0.0002 17 0 0 0 1.54E+09 6.36E+06 - - - 8.4426 1 221125_WJC_METTL3_EV_vs_WT_F04.21137.21137.2 2.88E-09 16/28 R.DEGAVISQISDISNR[166.11].D "sp|O75410|TACC1_HUMAN,tr|E7EVI4|E7EVI4_HUMAN,tr|E5RFM9|E5RFM9_HUMAN,tr|A0A0C4DGD5|A0A0C4DGD5_HUMAN,tr|R4GMT7|R4GMT7_HUMAN,tr|H0YAY0|H0YAY0_HUMAN,tr|A0A0C4DGD3|A0A0C4DGD3_HUMAN,tr|H0YBT8|H0YBT8_HUMAN,tr|E7ET87|E7ET87_HUMAN" 9 1612.7932 1.05 54169 21137 2 1612.791348 807.4039 Transforming acidic coiled-coil-containing protein 1 OS=Homo sapiens OX=9606 GN=TACC1 PE=1 SV=2 4.03 3423.7 - 3.04E+06 - - - -1.1477 - 3.482 0.661 - 1097.7 1 2 0 -0.0019 15 0 0 0 3.45E+07 3.28E+07 - - - 6.9899 0.9999 221125_WJC_METTL3_EV_vs_WT_F04.21143.21143.3 0.0491 15/60 K.KPELVISYLPPGMASK.L "sp|P78347|GTF2I_HUMAN,tr|A0A494C1K3|A0A494C1K3_HUMAN" 2 1728.9484 1.2 54175 21143 3 1728.951783 577.3234 General transcription factor II-I OS=Homo sapiens OX=9606 GN=GTF2I PE=1 SV=2 8.5 3424.1 - 1.75E+06 - - - 1.9399 - 2.493 0.417 - 276.7 1 2 0 0.0034 16 0 0 0 8.41E+06 7.02E+06 - - - 5.5321 1 221125_WJC_METTL3_EV_vs_WT_F04.21144.21144.3 2.29E-07 20/64 K.MSADNQLQVIFITNDRR.N "sp|Q9Y2L1|RRP44_HUMAN,tr|F2Z2C0|F2Z2C0_HUMAN,tr|G3V1J5|G3V1J5_HUMAN" 3 2020.016 1.51 54176 21144 3 2020.016713 674.3459 Exosome complex exonuclease RRP44 OS=Homo sapiens OX=9606 GN=DIS3 PE=1 SV=2 5.71 3424.2 - 1.43E+06 - - - 0.349 - 3.351 0.512 - 646.9 1 2 0 0.0007 17 0 0 0 2.99E+07 1.98E+07 - - - 7.3031 1 221125_WJC_METTL3_EV_vs_WT_F04.21147.21147.2 1.05E-12 20/32 R.AETEC[160.03]QNTEYQQLLDIK.L "sp|P13645|K1C10_HUMAN,tr|A0A1B0GVI3|A0A1B0GVI3_HUMAN" 2 2081.9576 999 54179 21147 2 2081.9582 1041.9861 "Keratin, type I cytoskeletal 10 OS=Homo sapiens OX=9606 GN=KRT10 PE=1 SV=6" 4 3424.6 - 1.08E+06 - - - 0.3122 - 4.07 0.706 - 1479 1 2 0 0.0006 17 0 0 0 9.06E+08 0.00E+00 - - - 7.7062 1 221125_WJC_METTL3_EV_vs_WT_F04.21149.21149.3 5.84E-12 23/100 R.IGLNNSPVNGNSSC[160.03]QMAFPSSQSLYR.T sp|Q12948|FOXC1_HUMAN 1 2827.3018 5.72 54181 21149 3 2827.300246 943.4412 Forkhead box protein C1 OS=Homo sapiens OX=9606 GN=FOXC1 PE=1 SV=3 8.22 3424.8 - 805396 - - - -0.5362 - 3.471 0.661 - 312.2 1 2 0 -0.0015 26 0 0 0 4.98E+06 8.71E+05 - - - 8.7721 0.9998 221125_WJC_METTL3_EV_vs_WT_F04.21152.21152.3 8.84E-07 13/88 K.ALYPSSVGQPFQGAYLEINK[136.11]NPK[136.11].Y "sp|O43795|MYO1B_HUMAN,tr|E9PDF6|E9PDF6_HUMAN,tr|H7C2Y7|H7C2Y7_HUMAN" 3 2536.3297 0.96 54184 21152 3 2536.325532 846.4505 Unconventional myosin-Ib OS=Homo sapiens OX=9606 GN=MYO1B PE=1 SV=3 8.47 3425.2 - 437581 - - - -1.6335 - 2.8 0.522 - 140.6 1 2 1 -0.0041 23 0 0 0 2.20E+06 2.29E+06 - - - 6.7741 0.9999 221125_WJC_METTL3_EV_vs_WT_F04.21153.21153.3 2.98E-05 Dec-56 K.DTVATQLSEAVDATR.G "sp|O60664|PLIN3_HUMAN,tr|K7ERZ3|K7ERZ3_HUMAN,tr|K7EL96|K7EL96_HUMAN" 3 1575.774 1.8 54185 21153 3 1575.7742 526.2653 Perilipin-3 OS=Homo sapiens OX=9606 GN=PLIN3 PE=1 SV=3 4.03 3425.3 - 436900 - - - 0.1079 - 2.299 0.397 - 198.8 1 2 0 0.0002 15 0 0 0 4.78E+06 2.66E+06 - - - 5.1383 0.9999 221125_WJC_METTL3_EV_vs_WT_F04.21156.21156.3 0.000226 16/60 K.K[136.11]PELVISYLPPGMASK[136.11].L "sp|P78347|GTF2I_HUMAN,tr|A0A494C1K3|A0A494C1K3_HUMAN" 2 1744.9768 1.28 54187 21156 3 1744.976477 582.6662 General transcription factor II-I OS=Homo sapiens OX=9606 GN=GTF2I PE=1 SV=2 8.5 3425.7 - 910568 - - - -0.2017 - 2.569 0.44 - 248.2 1 2 0 -0.0004 16 0 0 0 3.25E+07 2.53E+07 - - - 5.8664 1 221125_WJC_METTL3_EV_vs_WT_F04.21160.21160.3 9.57E-08 15/72 R.VNIAFNYDMPEDSDTYLHR.V "sp|Q13838|DX39B_HUMAN,tr|H0Y400|H0Y400_HUMAN,tr|Q5STU3|Q5STU3_HUMAN,tr|A0A0G2JJZ9|A0A0G2JJZ9_HUMAN,tr|A0A140T9X3|A0A140T9X3_HUMAN" 5 2299.0215 2.04 54190 21160 3 2299.0193 767.3478 Spliceosome RNA helicase DDX39B OS=Homo sapiens OX=9606 GN=DDX39B PE=1 SV=1 4.22 3426 - 5.20E+06 - - - -0.9774 - 3.062 0.61 - 225.6 1 2 0 -0.0022 19 0 0 0 4.15E+07 2.04E+07 - - - 8.0896 1 221125_WJC_METTL3_EV_vs_WT_F04.21161.21161.3 5.12E-12 17/72 R.VNIAFNYDMPEDSDTYLHR[166.11].V "sp|Q13838|DX39B_HUMAN,tr|H0Y400|H0Y400_HUMAN,tr|Q5STU3|Q5STU3_HUMAN,tr|A0A0G2JJZ9|A0A0G2JJZ9_HUMAN,tr|A0A140T9X3|A0A140T9X3_HUMAN" 5 2309.0298 2.04 54191 21161 3 2309.02521 770.6839 Spliceosome RNA helicase DDX39B OS=Homo sapiens OX=9606 GN=DDX39B PE=1 SV=1 4.22 3426.1 - 3.21E+06 - - - -1.9952 - 3.378 0.673 - 270.8 1 2 0 -0.0046 19 0 0 0 4.15E+07 2.04E+07 - - - 9.0326 1 221125_WJC_METTL3_EV_vs_WT_F04.21162.21162.3 2.99E-07 14/64 K.MSADNQLQVIFITNDR[166.11]R[166.11].N "sp|Q9Y2L1|RRP44_HUMAN,tr|F2Z2C0|F2Z2C0_HUMAN,tr|G3V1J5|G3V1J5_HUMAN" 3 2040.0325 1.65 54192 21162 3 2040.034665 681.0181 Exosome complex exonuclease RRP44 OS=Homo sapiens OX=9606 GN=DIS3 PE=1 SV=2 5.71 3426.1 - 2.19E+06 - - - 1.0377 - 2.998 0.544 - 319.2 1 2 0 0.0021 17 0 0 0 2.91E+07 1.76E+07 - - - 7.3782 1 221125_WJC_METTL3_EV_vs_WT_F04.21166.21166.4 2.97E-06 24/108 K.K[136.11]ISSIQSIVPALEIANAHR[166.11].K "sp|P10809|CH60_HUMAN,tr|A0A7I2V2X6|A0A7I2V2X6_HUMAN,tr|A0A7I2YQK6|A0A7I2YQK6_HUMAN,tr|A0A7I2V599|A0A7I2V599_HUMAN,tr|A0A7I2YQ71|A0A7I2YQ71_HUMAN,tr|A0A7I2V5M1|A0A7I2V5M1_HUMAN,tr|A0A7I2V5K3|A0A7I2V5K3_HUMAN,tr|A0A7I2V369|A0A7I2V369_HUMAN" 8 2064.181 1.53 54196 21166 4 2064.17849 517.0525 "60 kDa heat shock protein, mitochondrial OS=Homo sapiens OX=9606 GN=HSPD1 PE=1 SV=2" 8.75 3426.5 - 1.12E+06 - - - -1.2368 - 4.149 0.593 - 597.6 1 2 0 -0.0026 19 0 0 0 2.34E+07 1.54E+07 - - - 4.8681 1 221125_WJC_METTL3_EV_vs_WT_F04.21168.21168.3 2.86E-05 14/72 K.LTLQPVDNSTISLQMGTNK[136.11].V sp|Q15417|CNN3_HUMAN 1 2067.0762 0.3 54198 21168 3 2067.077519 690.0327 Calponin-3 OS=Homo sapiens OX=9606 GN=CNN3 PE=1 SV=1 5.84 3426.7 - 796521 - - - 0.6599 - 2.717 0.444 - 192.4 1 2 0 0.0014 19 0 0 0 2.63E+06 8.87E+06 - - - 5.9454 1 221125_WJC_METTL3_EV_vs_WT_F04.21170.21170.3 3.15E-11 16/56 R.QWQYDANPFLQSVHR.C "sp|Q96RN5|MED15_HUMAN,tr|G3V1P5|G3V1P5_HUMAN" 2 1887.9016 6.05 54200 21170 3 1887.89884 630.3078 Mediator of RNA polymerase II transcription subunit 15 OS=Homo sapiens OX=9606 GN=MED15 PE=1 SV=2 6.74 3427 - 720870 - - - -1.4778 - 2.912 0.622 - 455.8 1 2 0 -0.0028 15 0 0 0 3.13E+07 5.17E+06 - - - 8.2629 1 221125_WJC_METTL3_EV_vs_WT_F04.21171.21171.4 2.14E-07 18/84 K.FGHEFLEFEFR[166.11]PDGK[136.11].L "sp|Q96A72|MGN2_HUMAN,sp|P61326|MGN_HUMAN,tr|F5H6N1|F5H6N1_HUMAN" 3 1871.8962 1.68 54201 21171 4 1871.893878 468.9813 Protein mago nashi homolog 2 OS=Homo sapiens OX=9606 GN=MAGOHB PE=1 SV=1 4.83 3427.1 - 619939 - - - -1.2159 - 3.084 0.509 - 344.4 1 2 0 -0.0023 15 0 0 0 1.90E+08 1.13E+08 - - - 4.0587 0.9996 221125_WJC_METTL3_EV_vs_WT_F04.21172.21172.3 0.000244 Sep-72 K.LTLQPVDNSTISLQMGTNK.V sp|Q15417|CNN3_HUMAN 1 2059.062 0.3 54202 21172 3 2059.057841 687.3613 Calponin-3 OS=Homo sapiens OX=9606 GN=CNN3 PE=1 SV=1 5.84 3427.2 - 584474 - - - -1.998 - 1.979 0.374 - 56.5 1 2 0 -0.0041 19 0 0 0 2.63E+06 8.87E+06 - - - 4.3856 1 221125_WJC_METTL3_EV_vs_WT_F04.21173.21173.2 5.08E-12 19/36 K.DATNVGDEGGFAPNILENK.E "sp|P06733|ENOA_HUMAN,tr|A0A2R8Y6G6|A0A2R8Y6G6_HUMAN" 2 1959.9174 1.77 54203 21173 2 1959.911545 980.966 Alpha-enolase OS=Homo sapiens OX=9606 GN=ENO1 PE=1 SV=2 3.92 3427.4 - 412270 - - - -2.9874 - 3.656 0.699 - 843.3 1 2 0 -0.0059 19 0 0 0 2.65E+08 1.50E+08 - - - 7.3892 1 221125_WJC_METTL3_EV_vs_WT_F04.21182.21182.3 1.79E-09 18/72 K.DATNVGDEGGFAPNILENK[136.11].E "sp|P06733|ENOA_HUMAN,tr|A0A2R8Y6G6|A0A2R8Y6G6_HUMAN" 2 1967.9316 2.12 54210 21182 3 1967.92807 656.9845 Alpha-enolase OS=Homo sapiens OX=9606 GN=ENO1 PE=1 SV=2 3.92 3428.4 - 1.22E+06 - - - -1.7938 - 3.149 0.676 - 354.1 1 2 0 -0.0035 19 0 0 0 1.92E+08 9.03E+07 - - - 8.8939 0.9744 221125_WJC_METTL3_EV_vs_WT_F04.21183.21183.2 0.9 May-40 K.QDVLC[160.03]LC[160.03]FSPSEETLVASTSK.N "sp|Q96MR6|CFA57_HUMAN,tr|A0A087WVY5|A0A087WVY5_HUMAN" 2 2370.1083 999 54211 21183 2 2370.112055 1186.0614 Cilia- and flagella-associated protein 57 OS=Homo sapiens OX=9606 GN=CFAP57 PE=2 SV=3 4.14 3428.5 - 1.22E+06 - - - 1.5784 - 1.12 0.185 - 33.6 5 2 0 0.0037 21 0 0 0 1.28E+08 0.00E+00 - - - 0.3726 1 221125_WJC_METTL3_EV_vs_WT_F04.21186.21186.3 1.14E-09 22/56 K.FGHEFLEFEFR[166.11]PDGK[136.11].L "sp|Q96A72|MGN2_HUMAN,sp|P61326|MGN_HUMAN,tr|F5H6N1|F5H6N1_HUMAN" 3 1871.8962 1.86 54214 21186 3 1871.885329 624.9727 Protein mago nashi homolog 2 OS=Homo sapiens OX=9606 GN=MAGOHB PE=1 SV=1 4.83 3428.9 - 908293 - - - -5.7829 - 3.534 0.616 - 808.5 1 2 0 -0.0108 15 0 0 0 9.35E+07 5.04E+07 - - - 8.6989 1 221125_WJC_METTL3_EV_vs_WT_F04.21187.21187.2 1.83E-09 15/30 K.SENQEFYQDTFGQQWK.- "sp|O60506|HNRPQ_HUMAN,tr|A0A7I2V2F2|A0A7I2V2F2_HUMAN,tr|A0A7I2V309|A0A7I2V309_HUMAN" 3 2033.8755 3.5 54215 21187 2 2033.871801 1017.945 Heterogeneous nuclear ribonucleoprotein Q OS=Homo sapiens OX=9606 GN=SYNCRIP PE=1 SV=2 4.14 3429.1 - 724157 - - - -1.8359 - 3.188 0.715 - 978.9 1 2 0 -0.0037 16 0 0 0 4.57E+06 1.31E+06 - - - 7.1712 1 221125_WJC_METTL3_EV_vs_WT_F04.21194.21194.4 2.96E-08 18/84 K.FGHEFLEFEFRPDGK.L "sp|Q96A72|MGN2_HUMAN,sp|P61326|MGN_HUMAN,tr|F5H6N1|F5H6N1_HUMAN" 3 1853.8737 1.68 54220 21194 4 1853.869395 464.4757 Protein mago nashi homolog 2 OS=Homo sapiens OX=9606 GN=MAGOHB PE=1 SV=1 4.83 3430 - 7.52E+06 - - - -2.3135 - 3.309 0.543 - 397.4 1 2 0 -0.0043 15 0 0 0 1.90E+08 1.13E+08 - - - 4.3793 1 221125_WJC_METTL3_EV_vs_WT_F04.21196.21196.3 3.96E-10 20/72 K.DATNVGDEGGFAPNILENK.E "sp|P06733|ENOA_HUMAN,tr|A0A2R8Y6G6|A0A2R8Y6G6_HUMAN" 2 1959.9174 2.12 54222 21196 3 1959.91501 654.3131 Alpha-enolase OS=Homo sapiens OX=9606 GN=ENO1 PE=1 SV=2 3.92 3430.1 - 6.27E+06 - - - -1.2194 - 3.441 0.621 - 395.4 1 2 0 -0.0024 19 0 0 0 1.92E+08 9.03E+07 - - - 8.4989 1 221125_WJC_METTL3_EV_vs_WT_F04.21197.21197.2 8.46E-12 23/36 K.DATNVGDEGGFAPNILENK[136.11].E "sp|P06733|ENOA_HUMAN,tr|A0A2R8Y6G6|A0A2R8Y6G6_HUMAN" 2 1967.9316 1.77 54223 21197 2 1967.93074 984.9731 Alpha-enolase OS=Homo sapiens OX=9606 GN=ENO1 PE=1 SV=2 3.92 3430.2 - 4.42E+06 - - - -0.437 - 4.248 0.693 - 1526.4 1 2 0 -0.0009 19 0 0 0 2.65E+08 1.50E+08 - - - 7.7154 1 221125_WJC_METTL3_EV_vs_WT_F04.21198.21198.4 4.84E-13 26/156 R.VIISAPSADAPMFVMGVNHEKYDNSLK.L "sp|P04406|G3P_HUMAN,tr|E7EUT5|E7EUT5_HUMAN" 2 2932.4463 1.1 54224 21198 4 2932.439452 734.1189 Glyceraldehyde-3-phosphate dehydrogenase OS=Homo sapiens OX=9606 GN=GAPDH PE=1 SV=3 5.38 3430.2 - 3.86E+06 - - - -2.3356 - 4.589 0.647 - 358.8 1 2 1 -0.0068 27 0 0 0 1.10E+08 1.01E+08 - - - 5.3323 0.9999 221125_WJC_METTL3_EV_vs_WT_F04.21200.21200.3 4.03E-07 Nov-56 K.SAFPFSDKLGELSDK.L sp|Q14677|EPN4_HUMAN 1 1639.8094 1.67 54226 21200 3 1639.811091 547.6104 Clathrin interactor 1 OS=Homo sapiens OX=9606 GN=CLINT1 PE=1 SV=1 4.56 3430.4 - 2.40E+06 - - - 1.0599 - 2.919 0.546 - 75.2 1 2 1 0.0017 15 0 0 0 6.18E+07 3.71E+07 - - - 7.4221 1 221125_WJC_METTL3_EV_vs_WT_F04.21201.21201.3 2.83E-08 18/56 R.GFGFVTFDDHDPVDK.L "sp|P22626|ROA2_HUMAN,tr|A0A7I2V4N0|A0A7I2V4N0_HUMAN,tr|A0A024RA28|A0A024RA28_HUMAN,tr|A0A7I2V4N1|A0A7I2V4N1_HUMAN,tr|A0A7I2V4I6|A0A7I2V4I6_HUMAN,tr|A0A087WUI2|A0A087WUI2_HUMAN,tr|A0A7I2V4S4|A0A7I2V4S4_HUMAN,tr|A0A7I2V323|A0A7I2V323_HUMAN,tr|A0A7I2V3P1|A0A7I2V3P1_HUMAN,tr|A0A7I2V3P7|A0A7I2V3P7_HUMAN" 10 1694.7577 1.31 54227 21201 3 1694.752471 565.9265 Heterogeneous nuclear ribonucleoproteins A2\B1 OS=Homo sapiens OX=9606 GN=HNRNPA2B1 PE=1 SV=2 4.13 3430.5 - 2.03E+06 - - - -3.0565 - 2.979 0.628 - 257.9 1 2 0 -0.0052 15 0 0 0 1.56E+08 1.19E+08 - - - 8.3885 0.9999 221125_WJC_METTL3_EV_vs_WT_F04.21208.21208.3 15.2 19/56 R.GFGFVTFDDHDPVDK[136.11].L "sp|P22626|ROA2_HUMAN,tr|A0A7I2V4N0|A0A7I2V4N0_HUMAN,tr|A0A024RA28|A0A024RA28_HUMAN,tr|A0A7I2V4N1|A0A7I2V4N1_HUMAN,tr|A0A7I2V4I6|A0A7I2V4I6_HUMAN,tr|A0A087WUI2|A0A087WUI2_HUMAN,tr|A0A7I2V4S4|A0A7I2V4S4_HUMAN,tr|A0A7I2V323|A0A7I2V323_HUMAN,tr|A0A7I2V3P1|A0A7I2V3P1_HUMAN,tr|A0A7I2V3P7|A0A7I2V3P7_HUMAN" 10 1702.7719 1.31 54232 21208 3 1702.767264 568.5979 Heterogeneous nuclear ribonucleoproteins A2\B1 OS=Homo sapiens OX=9606 GN=HNRNPA2B1 PE=1 SV=2 4.13 3431.2 - 3.66E+06 - - - -2.6938 - 3.121 0.479 - 308.5 1 2 0 -0.0046 15 0 0 0 1.56E+08 1.19E+08 - - - 6.849 1 221125_WJC_METTL3_EV_vs_WT_F04.21209.21209.3 5.20E-06 40/84 K.GPAVGIDLGTTYSC[160.03]VGVFQHGK[136.11].V "sp|P11142|HSP7C_HUMAN,tr|E9PQQ4|E9PQQ4_HUMAN,tr|E9PNE6|E9PNE6_HUMAN,tr|E9PKE3|E9PKE3_HUMAN,tr|E9PLF4|E9PLF4_HUMAN,tr|E9PI65|E9PI65_HUMAN,tr|E9PK54|E9PK54_HUMAN,tr|E9PN25|E9PN25_HUMAN,tr|E9PPY6|E9PPY6_HUMAN,tr|E9PQK7|E9PQK7_HUMAN" 10 2270.1245 0.14 54233 21209 3 2270.118481 757.7154 Heat shock cognate 71 kDa protein OS=Homo sapiens OX=9606 GN=HSPA8 PE=1 SV=1 6.73 3431.4 - 2.91E+06 - - - -2.6527 - 4.493 0.633 - 1966.2 1 2 0 -0.006 22 0 0 0 3.52E+08 2.56E+09 - - - 9.1579 0.7844 221125_WJC_METTL3_EV_vs_WT_F04.21210.21210.4 1.66 7/120 K.SSGESSPSEHSSSGVSTPC[160.03]LK.E "sp|Q9Y3M8|STA13_HUMAN,tr|H3BRG5|H3BRG5_HUMAN" 2 2105.9171 15.49 54234 21210 4 2105.910216 527.4866 StAR-related lipid transfer protein 13 OS=Homo sapiens OX=9606 GN=STARD13 PE=1 SV=2 5.38 3431.5 - 1.25E+06 - - - -3.2888 - 0.985 0.149 - 21.5 1 2 0 -0.0069 21 0 0 0 1.46E+07 9.40E+05 - - - 0.516 1 221125_WJC_METTL3_EV_vs_WT_F04.21211.21211.3 2.07E-08 13/60 K.SENQEFYQDTFGQQWK.- "sp|O60506|HNRPQ_HUMAN,tr|A0A7I2V2F2|A0A7I2V2F2_HUMAN,tr|A0A7I2V309|A0A7I2V309_HUMAN" 3 2033.8755 1.45 54235 21211 3 2033.875081 678.9658 Heterogeneous nuclear ribonucleoprotein Q OS=Homo sapiens OX=9606 GN=SYNCRIP PE=1 SV=2 4.14 3431.6 - 738179 - - - -0.2232 - 2.795 0.576 - 244 1 2 0 -0.0005 16 0 0 0 9.70E+06 6.71E+06 - - - 7.599 0.9989 221125_WJC_METTL3_EV_vs_WT_F04.21221.21221.3 7.33E-08 26/96 S.TNPAPGILGPPPPSFHLGGPAVGPR.G "sp|P43243|MATR3_HUMAN,tr|D6RE02|D6RE02_HUMAN,tr|B3KM87|B3KM87_HUMAN,tr|A8MXP9|A8MXP9_HUMAN,tr|D6RAY2|D6RAY2_HUMAN,tr|D6R991|D6R991_HUMAN,tr|A0A0R4J2E8|A0A0R4J2E8_HUMAN,tr|D6RAM9|D6RAM9_HUMAN,tr|D6RIA2|D6RIA2_HUMAN,tr|H0Y8T4|H0Y8T4_HUMAN,tr|D6REM6|D6REM6_HUMAN,tr|D6RBI2|D6RBI2_HUMAN" 12 2402.2859 1.77 54240 21221 3 2402.284901 801.7692 Matrin-3 OS=Homo sapiens OX=9606 GN=MATR3 PE=1 SV=2 9.44 3432.9 - 3.34E+06 - - - -0.4154 - 3.799 0.594 - 695.1 1 1 0 -0.001 25 0 0 0 2.41E+08 1.36E+08 - - - 8.233 0.9993 221125_WJC_METTL3_EV_vs_WT_F04.21224.21224.3 3.72E-07 17/60 R.DLK[136.11]PSNLLINTTC[160.03]DLK[136.11].L "sp|P27361|MK03_HUMAN,sp|P28482|MK01_HUMAN,tr|H0YDH9|H0YDH9_HUMAN,tr|B3KR49|B3KR49_HUMAN,tr|E9PQW4|E9PQW4_HUMAN,tr|E9PJF0|E9PJF0_HUMAN,tr|E9PBK7|E9PBK7_HUMAN" 7 1859.9997 0.65 54242 21224 3 1860.999738 621.0072 Mitogen-activated protein kinase 3 OS=Homo sapiens OX=9606 GN=MAPK3 PE=1 SV=4 5.95 3433.2 - 960404 - - - 537.628 - 3.186 0.551 - 467.7 1 2 0 1 16 0 0 0 1.67E+07 2.58E+07 - - - 7.3793 1 221125_WJC_METTL3_EV_vs_WT_F04.21226.21226.3 4.60E-10 26/96 S.TNPAPGILGPPPPSFHLGGPAVGPR[166.11].G "sp|P43243|MATR3_HUMAN,tr|D6RE02|D6RE02_HUMAN,tr|B3KM87|B3KM87_HUMAN,tr|A8MXP9|A8MXP9_HUMAN,tr|D6RAY2|D6RAY2_HUMAN,tr|D6R991|D6R991_HUMAN,tr|A0A0R4J2E8|A0A0R4J2E8_HUMAN,tr|D6RAM9|D6RAM9_HUMAN,tr|D6RIA2|D6RIA2_HUMAN,tr|H0Y8T4|H0Y8T4_HUMAN,tr|D6REM6|D6REM6_HUMAN,tr|D6RBI2|D6RBI2_HUMAN" 12 2412.2942 1.77 54244 21226 3 2412.289788 805.1053 Matrin-3 OS=Homo sapiens OX=9606 GN=MATR3 PE=1 SV=2 9.44 3433.4 - 2.25E+06 - - - -1.8161 - 4.475 0.641 - 745.3 1 1 0 -0.0044 25 0 0 0 2.41E+08 1.36E+08 - - - 9.1328 0.9972 221125_WJC_METTL3_EV_vs_WT_F04.21230.21230.3 0.000306 14/60 K.ELEEAVTSALQQETEK.S "sp|Q9UPN3|MACF1_HUMAN,tr|H3BQK9|H3BQK9_HUMAN,tr|A0A7P0MQR8|A0A7P0MQR8_HUMAN,tr|E9PNZ4|E9PNZ4_HUMAN,tr|H0Y390|H0Y390_HUMAN,tr|H3BPE1|H3BPE1_HUMAN,tr|A0A590UJG2|A0A590UJG2_HUMAN" 7 1803.8738 4.56 54246 21230 3 1803.863769 602.2985 "Microtubule-actin cross-linking factor 1, isoforms 1\2\3\5 OS=Homo sapiens OX=9606 GN=MACF1 PE=1 SV=4" 3.98 3433.9 - 789629 - - - -5.563 - 2.347 0.388 - 243.5 1 2 0 -0.01 16 0 0 0 1.39E+07 3.05E+06 - - - 5.0521 0.9999 221125_WJC_METTL3_EV_vs_WT_F04.21236.21236.2 3.94E-06 14/24 K.QTADFLQEYVTNK[136.11].T "sp|Q9ULX6|AKP8L_HUMAN,tr|A0A7P0TAJ5|A0A7P0TAJ5_HUMAN,tr|A0A7P0TAE3|A0A7P0TAE3_HUMAN" 3 1563.766 0.94 54250 21236 2 1563.767423 782.8903 A-kinase anchor protein 8-like OS=Homo sapiens OX=9606 GN=AKAP8L PE=1 SV=4 4.37 3434.7 - 1.41E+06 - - - 0.8857 - 2.75 0.478 - 787.7 1 2 0 0.0014 13 0 0 0 3.06E+07 3.26E+07 - - - 5.1674 0.9997 221125_WJC_METTL3_EV_vs_WT_F04.21239.21239.2 2.48E-06 13/24 K.QTADFLQEYVTNK.T "sp|Q9ULX6|AKP8L_HUMAN,tr|A0A7P0TAJ5|A0A7P0TAJ5_HUMAN,tr|A0A7P0TAE3|A0A7P0TAE3_HUMAN" 3 1555.7518 0.93 54253 21239 2 1555.752506 778.8832 A-kinase anchor protein 8-like OS=Homo sapiens OX=9606 GN=AKAP8L PE=1 SV=4 4.37 3435.1 - 1.09E+06 - - - 0.4294 - 2.173 0.339 - 376.3 1 2 0 0.0007 13 0 0 0 3.04E+07 3.26E+07 - - - 3.5365 0.9999 221125_WJC_METTL3_EV_vs_WT_F04.21244.21244.3 0.00173 18/64 R.HLQLAIRGDEELDSLIK.A "sp|P0C0S5|H2AZ_HUMAN,sp|Q71UI9|H2AV_HUMAN,tr|C9J386|C9J386_HUMAN,tr|C9J0D1|C9J0D1_HUMAN,tr|A0A494C189|A0A494C189_HUMAN" 5 1949.0582 1.32 54256 21244 3 1949.056287 650.6933 Histone H2A.Z OS=Homo sapiens OX=9606 GN=H2AZ1 PE=1 SV=2 4.75 3435.6 - 2.34E+06 - - - -0.9769 - 3.401 0.5 - 421 1 2 1 -0.0019 17 0 0 0 8.94E+07 6.78E+07 - - - 7.2063 1 221125_WJC_METTL3_EV_vs_WT_F04.21246.21246.2 6.57E-14 20/42 K.GPAVGIDLGTTYSC[160.03]VGVFQHGK[136.11].V "sp|P11142|HSP7C_HUMAN,tr|E9PQQ4|E9PQQ4_HUMAN,tr|E9PNE6|E9PNE6_HUMAN,tr|E9PKE3|E9PKE3_HUMAN,tr|E9PLF4|E9PLF4_HUMAN,tr|E9PI65|E9PI65_HUMAN,tr|E9PK54|E9PK54_HUMAN,tr|E9PN25|E9PN25_HUMAN,tr|E9PPY6|E9PPY6_HUMAN,tr|E9PQK7|E9PQK7_HUMAN" 10 2270.1245 0.03 54258 21246 2 2270.122708 1136.0695 Heat shock cognate 71 kDa protein OS=Homo sapiens OX=9606 GN=HSPA8 PE=1 SV=1 6.73 3435.9 - 1.16E+06 - - - -0.7907 - 3.897 0.714 - 1102 1 2 0 -0.0018 22 0 0 0 6.80E+05 2.39E+07 - - - 7.6582 0.9999 221125_WJC_METTL3_EV_vs_WT_F04.21247.21247.4 1.25E-06 17/96 R.HLQLAIRGDEELDSLIK.A "sp|P0C0S5|H2AZ_HUMAN,sp|Q71UI9|H2AV_HUMAN,tr|C9J386|C9J386_HUMAN,tr|C9J0D1|C9J0D1_HUMAN,tr|A0A494C189|A0A494C189_HUMAN" 5 1949.0582 1.28 54259 21247 4 1949.057332 488.2718 Histone H2A.Z OS=Homo sapiens OX=9606 GN=H2AZ1 PE=1 SV=2 4.75 3436 - 1.05E+06 - - - -0.4407 - 2.887 0.493 - 234.8 1 2 1 -0.0009 17 0 0 0 2.76E+07 2.16E+07 - - - 3.8849 0.9998 221125_WJC_METTL3_EV_vs_WT_F04.21251.21251.3 0.00305 19/64 R.HLQLAIR[166.11]GDEELDSLIK[136.11].A "sp|P0C0S5|H2AZ_HUMAN,sp|Q71UI9|H2AV_HUMAN,tr|C9J386|C9J386_HUMAN,tr|C9J0D1|C9J0D1_HUMAN,tr|A0A494C189|A0A494C189_HUMAN" 5 1967.0807 1.32 54261 21251 3 1967.08069 656.7008 Histone H2A.Z OS=Homo sapiens OX=9606 GN=H2AZ1 PE=1 SV=2 4.75 3436.5 - 3.37E+06 - - - 0.0147 - 3.058 0.434 - 482.4 1 2 1 0 17 0 0 0 8.94E+07 6.78E+07 - - - 6.2025 1 221125_WJC_METTL3_EV_vs_WT_F04.21254.21254.3 1.26E-19 27/88 K.C[160.03]DYMDEVTYGELEKEEAQPIVTK.Y "sp|Q1KMD3|HNRL2_HUMAN,tr|H3BQZ7|H3BQZ7_HUMAN" 2 2746.2354 1.57 54264 21254 3 2746.231142 916.4191 Heterogeneous nuclear ribonucleoprotein U-like protein 2 OS=Homo sapiens OX=9606 GN=HNRNPUL2 PE=1 SV=1 4 3436.8 - 1.87E+06 - - - -1.5377 - 4.544 0.838 - 718.3 1 2 1 -0.0042 23 0 0 0 3.52E+07 2.24E+07 - - - 11.433 1 221125_WJC_METTL3_EV_vs_WT_F04.21255.21255.3 1.24E-11 18/92 K.GILGYTEHQVVSSDFNSDTHSSTF.D "sp|P04406|G3P_HUMAN,tr|E7EUT5|E7EUT5_HUMAN" 2 2627.1776 - 54265 21255 3 2627.176339 876.7331 Glyceraldehyde-3-phosphate dehydrogenase OS=Homo sapiens OX=9606 GN=GAPDH PE=1 SV=3 4.52 3437 - 1.25E+06 - - - -0.4762 - 4.006 0.685 - 244.4 1 1 0 -0.0013 24 0 0 0 - - - - - 9.4 1 221125_WJC_METTL3_EV_vs_WT_F04.21256.21256.3 1.74E-14 23/88 K.C[160.03]DYMDEVTYGELEK[136.11]EEAQPIVTK[136.11].Y "sp|Q1KMD3|HNRL2_HUMAN,tr|H3BQZ7|H3BQZ7_HUMAN" 2 2762.2638 1.57 54266 21256 3 2762.267193 921.7619 Heterogeneous nuclear ribonucleoprotein U-like protein 2 OS=Homo sapiens OX=9606 GN=HNRNPUL2 PE=1 SV=1 4 3437.1 - 1.14E+06 - - - 1.241 - 3.452 0.759 - 456.8 1 2 1 0.0034 23 0 0 0 3.52E+07 2.24E+07 - - - 9.9077 1 221125_WJC_METTL3_EV_vs_WT_F04.21260.21260.3 1.60E-08 15/80 K.SATIVADLSETTIQTPDGEER.L "sp|Q9NRG9|AAAS_HUMAN,tr|H3BU82|H3BU82_HUMAN,tr|F8VZ44|F8VZ44_HUMAN,tr|F8VUB6|F8VUB6_HUMAN" 4 2232.0758 0.43 54268 21260 3 2232.070891 745.0325 Aladin OS=Homo sapiens OX=9606 GN=AAAS PE=1 SV=1 3.83 3437.5 - 1.92E+06 - - - -2.1773 - 3.155 0.586 - 243.5 1 2 0 -0.0049 21 0 0 0 2.04E+07 4.72E+07 - - - 7.8266 1 221125_WJC_METTL3_EV_vs_WT_F04.21262.21262.3 2.54E-08 20/96 K.YGGPPPDSVYSGQQPSVGTEIFVGK.L "sp|O60506|HNRPQ_HUMAN,tr|A0A7I2YQN2|A0A7I2YQN2_HUMAN,tr|A0A7I2V5Q6|A0A7I2V5Q6_HUMAN,tr|A0A7I2V4Z0|A0A7I2V4Z0_HUMAN,tr|B7Z645|B7Z645_HUMAN,tr|A0A7I2V2F2|A0A7I2V2F2_HUMAN,tr|F6UXX1|F6UXX1_HUMAN,tr|A0A7I2V309|A0A7I2V309_HUMAN" 8 2565.2387 1.37 54270 21262 3 2565.23852 856.0869 Heterogeneous nuclear ribonucleoprotein Q OS=Homo sapiens OX=9606 GN=SYNCRIP PE=1 SV=2 4.37 3437.8 - 1.35E+06 - - - -0.0834 - 3.527 0.57 - 313.7 1 2 0 -0.0002 25 0 0 0 5.82E+07 4.25E+07 - - - 7.7947 1 221125_WJC_METTL3_EV_vs_WT_F04.21264.21264.3 2.93E-13 22/64 R.HVLLQEEVAELQGQVQR.T sp|Q6P4E1|GOLM2_HUMAN 1 1975.0487 1.84 54272 21264 3 1975.04528 659.3568 Protein GOLM2 OS=Homo sapiens OX=9606 GN=GOLM2 PE=1 SV=2 4.75 3438.1 - 422995 - - - -1.726 - 4.842 0.569 - 890.5 1 2 0 -0.0034 17 0 0 0 1.86E+07 1.01E+07 - - - 8.8677 1 221125_WJC_METTL3_EV_vs_WT_F04.21266.21266.3 1.38E-12 25/84 K.GPAVGIDLGTTYSC[160.03]VGVFQHGK.V "sp|P11142|HSP7C_HUMAN,tr|E9PQQ4|E9PQQ4_HUMAN,tr|E9PNE6|E9PNE6_HUMAN,tr|E9PKE3|E9PKE3_HUMAN,tr|E9PLF4|E9PLF4_HUMAN,tr|E9PI65|E9PI65_HUMAN,tr|E9PK54|E9PK54_HUMAN,tr|E9PN25|E9PN25_HUMAN,tr|E9PPY6|E9PPY6_HUMAN,tr|E9PQK7|E9PQK7_HUMAN" 10 2262.1103 0.14 54273 21266 3 2262.111174 755.044 Heat shock cognate 71 kDa protein OS=Homo sapiens OX=9606 GN=HSPA8 PE=1 SV=1 6.73 3438.3 - 2.04E+07 - - - 0.385 - 3.772 0.705 - 530.9 1 2 0 0.0009 22 0 0 0 3.51E+08 2.55E+09 - - - 9.5473 0.9999 221125_WJC_METTL3_EV_vs_WT_F04.21268.21268.3 3.89E-07 22/76 R.NALKQETEVELYNEFPEPIK.L "sp|P51149|RAB7A_HUMAN,tr|C9J4V0|C9J4V0_HUMAN,tr|C9J8S3|C9J8S3_HUMAN,tr|C9J4S4|C9J4S4_HUMAN,tr|A0A6Q8PGE6|A0A6Q8PGE6_HUMAN" 5 2390.2006 1.89 54274 21268 3 2390.19809 797.7408 Ras-related protein Rab-7a OS=Homo sapiens OX=9606 GN=RAB7A PE=1 SV=1 4.33 3438.5 - 3.46E+06 - - - -1.0325 - 3.377 0.494 - 638.2 1 2 1 -0.0025 20 0 0 0 5.37E+07 2.85E+07 - - - 6.9994 1 221125_WJC_METTL3_EV_vs_WT_F04.21274.21274.4 3.31E-07 25/126 K.GPAVGIDLGTTYSC[160.03]VGVFQHGK[136.11].V "sp|P11142|HSP7C_HUMAN,tr|E9PQQ4|E9PQQ4_HUMAN,tr|E9PNE6|E9PNE6_HUMAN,tr|E9PKE3|E9PKE3_HUMAN,tr|E9PLF4|E9PLF4_HUMAN,tr|E9PI65|E9PI65_HUMAN,tr|E9PK54|E9PK54_HUMAN,tr|E9PN25|E9PN25_HUMAN,tr|E9PPY6|E9PPY6_HUMAN,tr|E9PQK7|E9PQK7_HUMAN" 10 2270.1245 0.14 54278 21274 4 2270.12495 568.5384 Heat shock cognate 71 kDa protein OS=Homo sapiens OX=9606 GN=HSPA8 PE=1 SV=1 6.73 3439.1 - 1.73E+06 - - - 0.1969 - 3.051 0.515 - 379.7 1 2 0 0.0004 22 0 0 0 3.85E+06 2.81E+07 - - - 4.0734 1 221125_WJC_METTL3_EV_vs_WT_F04.21277.21277.3 4.09E-13 18/96 K.YGGPPPDSVYSGQQPSVGTEIFVGK[136.11].L "sp|O60506|HNRPQ_HUMAN,tr|A0A7I2YQN2|A0A7I2YQN2_HUMAN,tr|A0A7I2V5Q6|A0A7I2V5Q6_HUMAN,tr|A0A7I2V4Z0|A0A7I2V4Z0_HUMAN,tr|B7Z645|B7Z645_HUMAN,tr|A0A7I2V2F2|A0A7I2V2F2_HUMAN,tr|F6UXX1|F6UXX1_HUMAN,tr|A0A7I2V309|A0A7I2V309_HUMAN" 8 2573.2529 1.36 54281 21277 3 2573.249145 858.7583 Heterogeneous nuclear ribonucleoprotein Q OS=Homo sapiens OX=9606 GN=SYNCRIP PE=1 SV=2 4.37 3439.4 - 1.22E+06 - - - -1.4725 - 3.572 0.652 - 267.8 1 2 0 -0.0038 25 0 0 0 6.09E+07 4.46E+07 - - - 8.7371 1 221125_WJC_METTL3_EV_vs_WT_F04.21278.21278.3 6.25E-12 23/84 K.VTYHPDGPEGQAYDVDFTPPFR[166.11].R sp|Q15046|SYK_HUMAN 1 2517.1476 0.76 54282 21278 3 2517.144578 840.0565 Lysine--tRNA ligase OS=Homo sapiens OX=9606 GN=KARS1 PE=1 SV=3 4.22 3439.5 - 1.02E+06 - - - -1.2101 - 4.234 0.699 - 507.9 1 2 0 -0.003 22 0 0 0 2.46E+07 3.23E+07 - - - 9.7538 1 221125_WJC_METTL3_EV_vs_WT_F04.21286.21286.2 6.00E-09 14/22 K.DPNNLLNDWSQK[136.11].L sp|O00232|PSD12_HUMAN 1 1450.6932 0.5 54288 21286 2 1450.693109 726.3539 26S proteasome non-ATPase regulatory subunit 12 OS=Homo sapiens OX=9606 GN=PSMD12 PE=1 SV=3 4.21 3440.6 - 1.63E+06 - - - -0.0676 - 2.938 0.653 - 1128.4 1 2 0 -0.0001 12 0 0 0 2.55E+07 5.10E+07 - - - 6.6997 1 221125_WJC_METTL3_EV_vs_WT_F04.21292.21292.3 9.15E-10 20/104 R.VGMGSGSIC[160.03]ITQEVLAC[160.03]GR[166.11]PQATAVYK[136.11].V "sp|P12268|IMDH2_HUMAN,tr|A0A7I2V2T3|A0A7I2V2T3_HUMAN,tr|E7ETK5|E7ETK5_HUMAN" 3 2870.4208 0.32 54294 21292 3 2870.424603 957.8142 Inosine-5'-monophosphate dehydrogenase 2 OS=Homo sapiens OX=9606 GN=IMPDH2 PE=1 SV=2 8.02 3441.2 - 887739 - - - 1.3336 - 3.633 0.525 - 337.8 1 2 0 0.0038 27 0 0 0 4.11E+06 1.29E+07 - - - 7.3601 1 221125_WJC_METTL3_EV_vs_WT_F04.21294.21294.3 5.23E-07 13/48 K.FC[160.03]FSNEFSTFTHK.T "sp|Q9Y3B3|TMED7_HUMAN,tr|A0A0A6YYA0|A0A0A6YYA0_HUMAN" 2 1650.7137 1.69 54296 21294 3 1650.713471 551.2452 Transmembrane emp24 domain-containing protein 7 OS=Homo sapiens OX=9606 GN=TMED7 PE=1 SV=2 6.74 3441.4 - 757300 - - - -0.1254 - 2.494 0.598 - 122.3 1 2 0 -0.0002 13 0 0 0 1.48E+07 8.72E+06 - - - 7.6849 0.9999 221125_WJC_METTL3_EV_vs_WT_F04.21300.21300.3 0.00415 13/64 R.SC[160.03]PVVQSSQHLFLDLPK.L sp|P56192|SYMC_HUMAN 1 1953.9982 1.12 54300 21300 3 1953.99891 652.34 "Methionine--tRNA ligase, cytoplasmic OS=Homo sapiens OX=9606 GN=MARS1 PE=1 SV=2" 6.46 3442.2 - 1.28E+06 - - - 0.3465 - 2.767 0.402 - 163.5 1 2 0 0.0007 17 0 0 0 5.51E+07 4.93E+07 - - - 5.5929 1 221125_WJC_METTL3_EV_vs_WT_F04.21301.21301.3 2.51E-10 14/48 K.FC[160.03]FSNEFSTFTHK[136.11].T "sp|Q9Y3B3|TMED7_HUMAN,tr|A0A0A6YYA0|A0A0A6YYA0_HUMAN" 2 1658.7279 1.69 54301 21301 3 1658.725676 553.9166 Transmembrane emp24 domain-containing protein 7 OS=Homo sapiens OX=9606 GN=TMED7 PE=1 SV=2 6.74 3442.3 - 764993 - - - -1.3275 - 2.724 0.646 - 129.9 1 2 0 -0.0022 13 0 0 0 1.48E+07 8.72E+06 - - - 8.4586 1 221125_WJC_METTL3_EV_vs_WT_F04.21306.21306.3 5.01E-10 22/84 K.VTYHPDGPEGQAYDVDFTPPFR.R sp|Q15046|SYK_HUMAN 1 2507.1394 0.76 54304 21306 3 2507.141146 836.7204 Lysine--tRNA ligase OS=Homo sapiens OX=9606 GN=KARS1 PE=1 SV=3 4.22 3443 - 1.09E+06 - - - 0.7148 - 4.313 0.681 - 452.3 1 2 0 0.0018 22 0 0 0 2.46E+07 3.23E+07 - - - 9.5973 1 221125_WJC_METTL3_EV_vs_WT_F04.21307.21307.3 1.71E-08 17/64 R.SC[160.03]PVVQSSQHLFLDLPK[136.11].L sp|P56192|SYMC_HUMAN 1 1962.0124 1.11 54305 21307 3 1962.014438 655.0114 "Methionine--tRNA ligase, cytoplasmic OS=Homo sapiens OX=9606 GN=MARS1 PE=1 SV=2" 6.46 3443.1 - 755729 - - - 1.0219 - 3.483 0.581 - 278.1 1 2 0 0.002 17 0 0 0 5.47E+07 4.92E+07 - - - 8.1696 1 221125_WJC_METTL3_EV_vs_WT_F04.21308.21308.2 6.66E-07 16/22 R.EANELQQWINEK.E "sp|Q13813|SPTN1_HUMAN,tr|A0A0D9SF54|A0A0D9SF54_HUMAN,tr|A0A0D9SGF6|A0A0D9SGF6_HUMAN" 3 1500.7209 0.08 54306 21308 2 1500.724572 751.3677 "Spectrin alpha chain, non-erythrocytic 1 OS=Homo sapiens OX=9606 GN=SPTAN1 PE=1 SV=3" 4.25 3443.2 - 1.51E+06 - - - 2.4655 - 2.905 0.572 - 1196.4 1 2 0 0.0037 12 0 0 0 2.89E+07 3.74E+08 - - - 6.0706 0.9988 221125_WJC_METTL3_EV_vs_WT_F04.21311.21311.2 6.04E-06 18-Nov R.EC[160.03]LNLWGYER[166.11].V sp|Q86U44|MTA70_HUMAN 1 1348.6109 0.01 54309 21311 2 1348.616248 675.3127 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 4.53 3443.6 - 327970 - - - 3.9352 - 2.001 0.497 - 633.6 1 2 0 0.0053 10 0 0 0 1.60E+06 1.34E+08 - - - 4.6464 1 221125_WJC_METTL3_EV_vs_WT_F04.21314.21314.4 1.32E-11 27/114 R.PLFPHVLC[160.03]HNC[160.03]AVEFNFGQK.E "sp|Q00839|HNRPU_HUMAN,tr|A0A1W2PQL0|A0A1W2PQL0_HUMAN,tr|A0A1W2PPL4|A0A1W2PPL4_HUMAN,tr|A0A1W2PQ74|A0A1W2PQ74_HUMAN,tr|Q5RI18|Q5RI18_HUMAN,tr|A0A1W2PP35|A0A1W2PP35_HUMAN,tr|A0A1W2PPS1|A0A1W2PPS1_HUMAN,tr|A0A1W2PRZ7|A0A1W2PRZ7_HUMAN,tr|A0A1W2PPH7|A0A1W2PPH7_HUMAN,tr|A0A1W2PP34|A0A1W2PP34_HUMAN,tr|A0A1X7SBS1|A0A1X7SBS1_HUMAN" 11 2413.146 1.09 54310 21314 4 2413.146345 604.2938 Heterogeneous nuclear ribonucleoprotein U OS=Homo sapiens OX=9606 GN=HNRNPU PE=1 SV=6 7.24 3444 - 2.25E+06 - - - 0.1525 - 4.976 0.666 - 806.7 1 1 0 0.0004 20 0 0 0 2.51E+08 2.29E+08 - - - 5.5592 0.9985 221125_WJC_METTL3_EV_vs_WT_F04.21315.21315.4 2.33E-12 20/114 R.PLFPHVLC[160.03]HNC[160.03]AVEFNFGQK[136.11].E "sp|Q00839|HNRPU_HUMAN,tr|A0A1W2PQL0|A0A1W2PQL0_HUMAN,tr|A0A1W2PPL4|A0A1W2PPL4_HUMAN,tr|A0A1W2PQ74|A0A1W2PQ74_HUMAN,tr|Q5RI18|Q5RI18_HUMAN,tr|A0A1W2PP35|A0A1W2PP35_HUMAN,tr|A0A1W2PPS1|A0A1W2PPS1_HUMAN,tr|A0A1W2PRZ7|A0A1W2PRZ7_HUMAN,tr|A0A1W2PPH7|A0A1W2PPH7_HUMAN,tr|A0A1W2PP34|A0A1W2PP34_HUMAN,tr|A0A1X7SBS1|A0A1X7SBS1_HUMAN" 11 2421.1602 1.1 54311 21315 4 2421.160393 606.2973 Heterogeneous nuclear ribonucleoprotein U OS=Homo sapiens OX=9606 GN=HNRNPU PE=1 SV=6 7.24 3444.1 - 2.31E+06 - - - 0.0892 - 3.262 0.621 - 344.2 1 1 0 0.0002 20 0 0 0 2.52E+08 2.29E+08 - - - 5.0264 0.9964 221125_WJC_METTL3_EV_vs_WT_F04.21316.21316.4 0.000511 17/132 R.LLQGR[166.11]PPLDFYPPGVHPSGLVPR[166.11].E sp|P48634|PRC2A_HUMAN 1 2531.3916 0.78 54312 21316 4 2531.388513 633.8552 Protein PRRC2A OS=Homo sapiens OX=9606 GN=PRRC2A PE=1 SV=3 8.75 3444.2 - 1.40E+06 - - - -1.2151 - 3.063 0.224 - 143.2 1 2 0 -0.0031 23 0 0 0 2.97E+07 3.83E+07 - - - 1.5375 1 221125_WJC_METTL3_EV_vs_WT_F04.21323.21323.2 1.43E-07 14/28 R.VVSEDFLQDVSASTK.S "sp|P09874|PARP1_HUMAN,tr|A0A7I2V3E1|A0A7I2V3E1_HUMAN" 2 1623.7992 1.01 54317 21323 2 1623.804177 812.9069 Poly [ADP-ribose] polymerase 1 OS=Homo sapiens OX=9606 GN=PARP1 PE=1 SV=4 4.03 3445.1 - 884596 - - - 3.0761 - 2.631 0.622 - 467 1 2 0 0.005 15 0 0 0 2.00E+07 1.98E+07 - - - 6.0118 1 221125_WJC_METTL3_EV_vs_WT_F04.21325.21325.2 4.15E-08 16/28 R.VVSEDFLQDVSASTK[136.11].S "sp|P09874|PARP1_HUMAN,tr|A0A7I2V3E1|A0A7I2V3E1_HUMAN" 2 1631.8134 1.01 54319 21325 2 1631.814164 816.914 Poly [ADP-ribose] polymerase 1 OS=Homo sapiens OX=9606 GN=PARP1 PE=1 SV=4 4.03 3445.3 - 847514 - - - 0.4792 - 2.83 0.601 - 679.8 1 2 0 0.0008 15 0 0 0 2.00E+07 1.98E+07 - - - 6.0373 1 221125_WJC_METTL3_EV_vs_WT_F04.21329.21329.4 9.25E-08 22/150 R.TGHILHPEYLQPLPSTPVSPIELDAK.K sp|Q96F45|ZN503_HUMAN 1 2851.512 1.72 54321 21329 4 2851.513991 713.8853 Zinc finger protein 503 OS=Homo sapiens OX=9606 GN=ZNF503 PE=1 SV=1 5.26 3445.8 - 2.18E+06 - - - 0.6996 - 4.048 0.585 - 265.3 1 2 0 0.002 26 0 0 0 2.72E+07 1.58E+07 - - - 4.7583 0.9997 221125_WJC_METTL3_EV_vs_WT_F04.21330.21330.4 0.000197 20/132 R.LLQGRPPLDFYPPGVHPSGLVPR.E sp|P48634|PRC2A_HUMAN 1 2511.375 0.65 54322 21330 4 2511.378068 628.851 Protein PRRC2A OS=Homo sapiens OX=9606 GN=PRRC2A PE=1 SV=3 8.75 3445.9 - 2.01E+06 - - - 1.2021 - 3.172 0.352 - 186.7 1 2 0 0.003 23 0 0 0 2.97E+07 4.55E+07 - - - 2.663 1 221125_WJC_METTL3_EV_vs_WT_F04.21332.21332.3 7.96E-08 13/60 K.EEDAFHFVSYVPVNGR.L "sp|Q9Y5K5|UCHL5_HUMAN,tr|H0Y4E0|H0Y4E0_HUMAN,tr|Q5LJA9|Q5LJA9_HUMAN,tr|H0Y6Y4|H0Y6Y4_HUMAN,tr|Q5LJB0|Q5LJB0_HUMAN,tr|Q5LJA5|Q5LJA5_HUMAN" 6 1864.8744 1.62 54324 21332 3 1864.875346 622.6321 Ubiquitin carboxyl-terminal hydrolase isozyme L5 OS=Homo sapiens OX=9606 GN=UCHL5 PE=1 SV=3 4.65 3446.1 - 659410 - - - 0.5003 - 2.89 0.601 - 138.1 1 2 0 0.0009 16 0 0 0 7.92E+07 4.88E+07 - - - 7.9633 1 221125_WJC_METTL3_EV_vs_WT_F04.21334.21334.4 1.44E-05 22/114 K.IAELLENVTLIHK[136.11]PVSLQPR[166.11].G "sp|Q14694|UBP10_HUMAN,tr|J3KT19|J3KT19_HUMAN" 2 2287.3383 0.96 54326 21334 4 2287.336859 572.8418 Ubiquitin carboxyl-terminal hydrolase 10 OS=Homo sapiens OX=9606 GN=USP10 PE=1 SV=2 6.76 3446.3 - 426164 - - - -0.6177 - 3.761 0.539 - 378.5 1 2 0 -0.0014 20 0 0 0 1.06E+07 1.11E+07 - - - 4.3599 0.9994 221125_WJC_METTL3_EV_vs_WT_F04.21336.21336.3 0.000189 13/72 K.EQAGEAEGAQAVTQLMVDR[166.11].L "sp|O14617|AP3D1_HUMAN,tr|A0A2R8Y611|A0A2R8Y611_HUMAN" 2 2011.9508 0.61 54328 21336 3 2011.951987 671.6576 AP-3 complex subunit delta-1 OS=Homo sapiens OX=9606 GN=AP3D1 PE=1 SV=1 4 3446.6 - 177535 - - - 0.5706 - 2.338 0.276 - 216.7 1 2 0 0.0011 19 0 0 0 1.71E+06 2.82E+06 - - - 3.7034 1 221125_WJC_METTL3_EV_vs_WT_F04.21339.21339.4 4.12E-09 26/150 R.TGHILHPEYLQPLPSTPVSPIELDAK[136.11].K sp|Q96F45|ZN503_HUMAN 1 2859.5262 1.72 54329 21339 4 2859.523284 715.8888 Zinc finger protein 503 OS=Homo sapiens OX=9606 GN=ZNF503 PE=1 SV=1 5.26 3447 - 1.68E+06 - - - -1.0184 - 4.559 0.556 - 453.3 1 2 0 -0.0029 26 0 0 0 2.72E+07 1.58E+07 - - - 4.5432 1 221125_WJC_METTL3_EV_vs_WT_F04.21343.21343.3 1.94E-06 20/68 R.ELQGQIAAITGIAPGGQR.L sp|Q5VVQ6|OTU1_HUMAN 1 1778.9639 2.78 54333 21343 3 1778.965399 593.9952 Ubiquitin thioesterase OTU1 OS=Homo sapiens OX=9606 GN=YOD1 PE=1 SV=1 6.1 3447.5 - 640423 - - - 0.8449 - 3.118 0.499 - 414.8 1 2 0 0.0015 18 0 0 0 7.81E+06 2.81E+06 - - - 6.9347 0.9968 221125_WJC_METTL3_EV_vs_WT_F04.21347.21347.4 7.79E-06 19/90 L.R[166.11]DYLHLPPEIVPATLR[166.11].R "sp|P46783|RS10_HUMAN,tr|A0A2R8Y6L3|A0A2R8Y6L3_HUMAN,tr|F6U211|F6U211_HUMAN,tr|A0A1W2PQS6|A0A1W2PQS6_HUMAN,tr|A0A2R8YFH6|A0A2R8YFH6_HUMAN,tr|A0A2R8Y7H1|A0A2R8Y7H1_HUMAN,tr|S4R435|S4R435_HUMAN" 7 1909.0689 2.11 54337 21347 4 1909.070769 478.2745 40S ribosomal protein S10 OS=Homo sapiens OX=9606 GN=RPS10 PE=1 SV=1 6.75 3448 - 358250 - - - 1.0015 - 2.837 0.524 - 285.9 1 1 0 0.0019 16 0 0 0 1.52E+07 7.20E+06 - - - 4.1537 1 221125_WJC_METTL3_EV_vs_WT_F04.21348.21348.4 5.65E-07 16/96 K.LSSLIILMPHHVEPLER[166.11].L "sp|P50454|SERPH_HUMAN,tr|E9PKH2|E9PKH2_HUMAN,tr|E9PPV6|E9PPV6_HUMAN,tr|E9PR70|E9PR70_HUMAN,tr|E9PJH8|E9PJH8_HUMAN" 5 1993.1058 2.45 54338 21348 4 1993.10256 499.2837 Serpin H1 OS=Homo sapiens OX=9606 GN=SERPINH1 PE=1 SV=2 6 3448.2 - 163919 - - - -1.6371 - 3.394 0.541 - 274 1 2 0 -0.0033 17 0 0 0 3.65E+06 1.49E+06 - - - 4.3582 1 221125_WJC_METTL3_EV_vs_WT_F04.21349.21349.2 2.28E-09 Nov-36 R.AALETDENLLLC[160.03]APTGAGK.T "sp|O75643|U520_HUMAN,tr|A0A494C1A5|A0A494C1A5_HUMAN" 2 1942.967 5.11 54339 21349 2 1942.960549 972.4908 U5 small nuclear ribonucleoprotein 200 kDa helicase OS=Homo sapiens OX=9606 GN=SNRNP200 PE=1 SV=2 4.14 3448.3 - 233978 - - - -3.3166 - 2.473 0.67 - 261 1 2 0 -0.0064 19 0 0 0 2.30E+06 4.51E+05 - - - 6.2136 1 221125_WJC_METTL3_EV_vs_WT_F04.21353.21353.3 6.10E-13 29/76 R.PLFPHVLC[160.03]HNC[160.03]AVEFNFGQK.E "sp|Q00839|HNRPU_HUMAN,tr|A0A1W2PQL0|A0A1W2PQL0_HUMAN,tr|A0A1W2PPL4|A0A1W2PPL4_HUMAN,tr|A0A1W2PQ74|A0A1W2PQ74_HUMAN,tr|Q5RI18|Q5RI18_HUMAN,tr|A0A1W2PP35|A0A1W2PP35_HUMAN,tr|A0A1W2PPS1|A0A1W2PPS1_HUMAN,tr|A0A1W2PRZ7|A0A1W2PRZ7_HUMAN,tr|A0A1W2PPH7|A0A1W2PPH7_HUMAN,tr|A0A1W2PP34|A0A1W2PP34_HUMAN,tr|A0A1X7SBS1|A0A1X7SBS1_HUMAN" 11 2413.146 1.08 54341 21353 3 2413.146555 805.3893 Heterogeneous nuclear ribonucleoprotein U OS=Homo sapiens OX=9606 GN=HNRNPU PE=1 SV=6 7.24 3448.7 - 3.42E+06 - - - 0.2395 - 4.379 0.69 - 750 1 1 0 0.0006 20 0 0 0 4.41E+07 4.09E+07 - - - 9.8155 0.9997 221125_WJC_METTL3_EV_vs_WT_F04.21354.21354.3 0.000347 18/56 R.TK[136.11]EEALELINGYIQK[136.11].L "sp|Q13526|PIN1_HUMAN,tr|K7EMU7|K7EMU7_HUMAN,tr|K7EN45|K7EN45_HUMAN" 3 1763.964 1.53 54342 21354 3 1763.961567 588.9953 Peptidyl-prolyl cis-trans isomerase NIMA-interacting 1 OS=Homo sapiens OX=9606 GN=PIN1 PE=1 SV=1 4.78 3448.8 - 926592 - - - -1.3884 - 2.822 0.414 - 533.2 1 2 1 -0.0024 15 0 0 0 2.20E+07 1.45E+07 - - - 5.8621 1 221125_WJC_METTL3_EV_vs_WT_F04.21355.21355.3 4.89E-11 18/92 K.GLVEPVDVVDNADGTQTVNYVPSR[166.11].E "sp|P21333|FLNA_HUMAN,tr|Q60FE5|Q60FE5_HUMAN" 2 2553.2586 1 54343 21355 3 2553.257174 852.0935 Filamin-A OS=Homo sapiens OX=9606 GN=FLNA PE=1 SV=4 3.84 3448.9 - 3.49E+06 - - - -0.5706 - 3.062 0.498 - 212.9 1 2 0 -0.0015 24 0 0 0 3.08E+07 3.07E+07 - - - 6.691 1 221125_WJC_METTL3_EV_vs_WT_F04.21356.21356.3 3.42E-06 14/72 K.SGAWDESGVFIYTTSNHIK[136.11].Y "sp|P53621|COPA_HUMAN,tr|A0A3B3ISC6|A0A3B3ISC6_HUMAN,tr|A0A3B3ITV3|A0A3B3ITV3_HUMAN,tr|A0A3B3IS84|A0A3B3IS84_HUMAN,tr|A0A3B3IU89|A0A3B3IU89_HUMAN,tr|A0A3B3IT15|A0A3B3IT15_HUMAN" 6 2119.0102 1.23 54344 21356 3 2119.007842 707.344 Coatomer subunit alpha OS=Homo sapiens OX=9606 GN=COPA PE=1 SV=2 5.3 3449 - 1.52E+06 - - - -1.1052 - 2.51 0.546 - 140.9 1 2 0 -0.0023 19 0 0 0 2.79E+07 2.26E+07 - - - 6.8877 1 221125_WJC_METTL3_EV_vs_WT_F04.21358.21358.2 4.30E-08 16/32 R.LEQELFSGGNTGINFEK.Y "sp|O00571|DDX3X_HUMAN,sp|O15523|DDX3Y_HUMAN,tr|A0A2R8YFR4|A0A2R8YFR4_HUMAN,tr|A0A2R8YCW1|A0A2R8YCW1_HUMAN,tr|A0A2R8YDH3|A0A2R8YDH3_HUMAN,tr|A0A2R8Y645|A0A2R8Y645_HUMAN,tr|A0A2R8YF78|A0A2R8YF78_HUMAN,tr|C9J8G5|C9J8G5_HUMAN,tr|A0A2R8YCU0|A0A2R8YCU0_HUMAN,tr|A0A0D9SFB3|A0A0D9SFB3_HUMAN,tr|A0A2R8YFS5|A0A2R8YFS5_HUMAN,tr|A0A0D9SF53|A0A0D9SF53_HUMAN,tr|A0A2R8Y650|A0A2R8Y650_HUMAN,tr|C9J081|C9J081_HUMAN,tr|A0A2R8Y5G6|A0A2R8Y5G6_HUMAN,tr|A0A0D9SG12|A0A0D9SG12_HUMAN,tr|F6S8Q4|F6S8Q4_HUMAN,tr|A0A2U3TZJ9|A0A2U3TZJ9_HUMAN,tr|A0A2R8Y4A4|A0A2R8Y4A4_HUMAN" 19 1881.9109 1.67 54346 21358 2 1881.912242 941.9627 ATP-dependent RNA helicase DDX3X OS=Homo sapiens OX=9606 GN=DDX3X PE=1 SV=3 4.25 3449.3 - 363842 - - - 0.7354 - 3.44 0.573 - 972.2 1 2 0 0.0014 17 0 0 0 4.74E+06 2.84E+06 - - - 6.3102 1 221125_WJC_METTL3_EV_vs_WT_F04.21359.21359.3 5.66E-09 18/100 R.TGHILHPEYLQPLPSTPVSPIELDAK.K sp|Q96F45|ZN503_HUMAN 1 2851.512 2.4 54347 21359 3 2851.522616 951.5113 Zinc finger protein 503 OS=Homo sapiens OX=9606 GN=ZNF503 PE=1 SV=1 5.26 3449.4 - 357567 - - - 3.7243 - 4.461 0.607 - 311.3 1 2 0 0.0106 26 0 0 0 2.72E+06 1.13E+06 - - - 8.7448 0.9998 221125_WJC_METTL3_EV_vs_WT_F04.21361.21361.4 0.00247 Dec-72 K.DLIHDVSFDFHGR[166.11].R "sp|Q96EE3|SEH1_HUMAN,tr|K7EP88|K7EP88_HUMAN,tr|K7ENI5|K7ENI5_HUMAN,tr|K7ELV2|K7ELV2_HUMAN" 4 1566.7455 1.46 54349 21361 4 1566.744642 392.6936 Nucleoporin SEH1 OS=Homo sapiens OX=9606 GN=SEH1L PE=1 SV=3 5.13 3449.7 - 204821 - - - -0.5227 - 2.252 0.39 - 148.3 1 2 0 -0.0008 13 0 0 0 4.15E+06 2.83E+06 - - - 2.9213 1 221125_WJC_METTL3_EV_vs_WT_F04.21364.21364.3 3.07E-17 23/80 R.LASYLDKVQALEEANNDLENK.L sp|P35527|K1C9_HUMAN 1 2376.1809 981.98 54350 21364 3 2376.179994 793.0676 "Keratin, type I cytoskeletal 9 OS=Homo sapiens OX=9606 GN=KRT9 PE=1 SV=3" 4.18 3450.1 - 5.16E+06 - - - -0.375 - 4.524 0.709 - 699.7 1 2 1 -0.0009 21 0 0 0 5.50E+08 5.60E+05 - - - 10.0631 0.9998 221125_WJC_METTL3_EV_vs_WT_F04.21366.21366.3 1.57E-06 18/56 R.TKEEALELINGYIQK.L "sp|Q13526|PIN1_HUMAN,tr|K7EMU7|K7EMU7_HUMAN,tr|K7EN45|K7EN45_HUMAN" 3 1747.9356 1.53 54352 21366 3 1747.939579 583.6525 Peptidyl-prolyl cis-trans isomerase NIMA-interacting 1 OS=Homo sapiens OX=9606 GN=PIN1 PE=1 SV=1 4.78 3450.2 - 2.46E+06 - - - 2.2672 - 2.834 0.513 - 584.2 1 2 1 0.004 15 0 0 0 2.20E+07 1.45E+07 - - - 6.9765 1 221125_WJC_METTL3_EV_vs_WT_F04.21371.21371.3 7.63E-08 16/48 R.KVESLQEEIAFLK.K "sp|P08670|VIME_HUMAN,tr|B0YJC5|B0YJC5_HUMAN,tr|B0YJC4|B0YJC4_HUMAN" 3 1532.845 1.96 54357 21371 3 1532.845768 511.9556 Vimentin OS=Homo sapiens OX=9606 GN=VIM PE=1 SV=4 4.79 3450.9 - 448118 - - - 0.4945 - 3.318 0.552 - 605.7 1 2 0 0.0008 13 0 0 0 1.05E+08 5.39E+07 - - - 7.9459 1 221125_WJC_METTL3_EV_vs_WT_F04.21372.21372.4 1.79E-07 17/72 K.DLIHDVSFDFHGR.R "sp|Q96EE3|SEH1_HUMAN,tr|K7EP88|K7EP88_HUMAN,tr|K7ENI5|K7ENI5_HUMAN,tr|K7ELV2|K7ELV2_HUMAN" 4 1556.7372 1.46 54358 21372 4 1556.737567 390.1916 Nucleoporin SEH1 OS=Homo sapiens OX=9606 GN=SEH1L PE=1 SV=3 5.13 3451 - 416541 - - - 0.2415 - 2.924 0.498 - 297.4 1 2 0 0.0004 13 0 0 0 4.15E+06 2.83E+06 - - - 3.9583 0.8942 221125_WJC_METTL3_EV_vs_WT_F04.21376.21376.4 0.874 May-66 K.VPHWYHFSC[160.03]FWK[136.11].V "sp|P09874|PARP1_HUMAN,tr|A0A7I2V384|A0A7I2V384_HUMAN,tr|A0A7I2V5E9|A0A7I2V5E9_HUMAN,tr|A0A7I2V625|A0A7I2V625_HUMAN,tr|A0A7I2V3E1|A0A7I2V3E1_HUMAN" 5 1700.7802 0.68 54362 21376 4 1700.777485 426.2023 Poly [ADP-ribose] polymerase 1 OS=Homo sapiens OX=9606 GN=PARP1 PE=1 SV=4 8.19 3451.5 - 263430 - - - -1.5899 - 1.066 0.174 - 13.5 3 2 0 -0.0027 12 0 0 0 1.73E+06 2.53E+06 - - - 0.4003 0.9997 221125_WJC_METTL3_EV_vs_WT_F04.21380.21380.4 1.89E-05 19/144 R.VVTVSEYYLRPVSQQEFDKNTLDLR.Q sp|Q92917|GPKOW_HUMAN 1 2998.54 1.27 54364 21380 4 2998.543096 750.6423 G-patch domain and KOW motifs-containing protein OS=Homo sapiens OX=9606 GN=GPKOW PE=1 SV=2 4.78 3452.1 - 644618 - - - 1.0322 - 2.985 0.432 - 133.1 1 2 1 0.0031 25 0 0 0 4.99E+06 3.93E+06 - - - 3.3332 0.9953 221125_WJC_METTL3_EV_vs_WT_F04.21382.21382.4 9.05E-05 13/90 L.RDYLHLPPEIVPATLR.R "sp|P46783|RS10_HUMAN,tr|A0A2R8Y6L3|A0A2R8Y6L3_HUMAN,tr|F6U211|F6U211_HUMAN,tr|A0A1W2PQS6|A0A1W2PQS6_HUMAN,tr|A0A2R8YFH6|A0A2R8YFH6_HUMAN,tr|A0A2R8Y7H1|A0A2R8Y7H1_HUMAN,tr|S4R435|S4R435_HUMAN" 7 1889.0523 1.42 54366 21382 4 1889.054345 473.2704 40S ribosomal protein S10 OS=Homo sapiens OX=9606 GN=RPS10 PE=1 SV=1 6.75 3452.3 - 499649 - - - 1.0736 - 2.771 0.487 - 117.7 1 1 0 0.002 16 0 0 0 9.34E+06 6.57E+06 - - - 3.8233 1 221125_WJC_METTL3_EV_vs_WT_F04.21384.21384.3 9.78E-05 15/52 K.AAILPTSIFLTNKK.G "sp|O14744|ANM5_HUMAN,tr|H0YJX6|H0YJX6_HUMAN" 2 1515.9025 3.04 54368 21384 3 1515.903543 506.3081 Protein arginine N-methyltransferase 5 OS=Homo sapiens OX=9606 GN=PRMT5 PE=1 SV=4 10 3452.6 - 413813 - - - 0.7111 - 2.824 0.498 - 363.7 1 2 0 0.0011 14 0 0 0 7.91E+06 2.60E+06 - - - 6.8508 0.9999 221125_WJC_METTL3_EV_vs_WT_F04.21386.21386.3 0.000425 Oct-44 R.K[136.11]ALVDILSEVSK[136.11].A "sp|Q9BQG0|MBB1A_HUMAN,tr|I3L1L3|I3L1L3_HUMAN" 2 1316.7886 0.69 54370 21386 3 1316.786901 439.9368 Myb-binding protein 1A OS=Homo sapiens OX=9606 GN=MYBBP1A PE=1 SV=2 6.07 3452.9 - 174451 - - - -1.3039 - 2.011 0.461 - 203.6 1 2 0 -0.0017 12 0 0 0 1.17E+06 1.69E+06 - - - 5.6157 1 221125_WJC_METTL3_EV_vs_WT_F04.21390.21390.3 7.79E-11 16/64 K.VHYENNSPFLTITSMTR.V "sp|P04843|RPN1_HUMAN,tr|B7Z4L4|B7Z4L4_HUMAN" 2 2008.9677 1.34 54373 21390 3 2008.969092 670.6632 Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit 1 OS=Homo sapiens OX=9606 GN=RPN1 PE=1 SV=1 6.72 3453.3 - 852279 - - - 0.7123 - 3.467 0.616 - 352.1 1 2 0 0.0014 17 0 0 0 1.02E+07 7.62E+06 - - - 8.5483 1 221125_WJC_METTL3_EV_vs_WT_F04.21391.21391.3 1.23E-05 13/72 R.AIQTLGYFPVGDGDFPHQK.L "sp|Q5VYK3|ECM29_HUMAN,tr|J3KN16|J3KN16_HUMAN,tr|A0A804HJA4|A0A804HJA4_HUMAN,tr|R4GMY1|R4GMY1_HUMAN" 4 2089.0269 0.51 54374 21391 3 2089.028681 697.3496 Proteasome adapter and scaffold protein ECM29 OS=Homo sapiens OX=9606 GN=ECPAS PE=1 SV=2 5.21 3453.4 - 524446 - - - 0.8569 - 2.741 0.475 - 225.5 1 2 0 0.0018 19 0 0 0 5.69E+06 1.12E+07 - - - 6.3125 1 221125_WJC_METTL3_EV_vs_WT_F04.21392.21392.3 6.67E-08 20/92 R.FEEVEEEPEVIPGPPSESPGMLTK.L sp|O43395|PRPF3_HUMAN 1 2626.236 2.46 54375 21392 3 2626.239059 876.4193 U4\U6 small nuclear ribonucleoprotein Prp3 OS=Homo sapiens OX=9606 GN=PRPF3 PE=1 SV=2 3.83 3453.5 - 515631 - - - 1.1587 - 2.761 0.642 - 256.5 1 2 0 0.003 24 0 0 0 9.39E+06 3.82E+06 - - - 8.0556 0.9999 221125_WJC_METTL3_EV_vs_WT_F04.21393.21393.3 7.95E-06 Oct-60 K.EANHDGDFGITLAELR.A "sp|P20020|AT2B1_HUMAN,tr|F8W1V5|F8W1V5_HUMAN" 2 1756.838 1.45 54376 21393 3 1756.837365 586.62 Plasma membrane calcium-transporting ATPase 1 OS=Homo sapiens OX=9606 GN=ATP2B1 PE=1 SV=4 4.31 3453.7 - 370859 - - - -0.3768 - 1.923 0.415 - 147.6 1 2 0 -0.0007 16 0 0 0 3.07E+06 2.12E+06 - - - 4.8444 1 221125_WJC_METTL3_EV_vs_WT_F04.21394.21394.3 1.20E-07 Oct-44 R.FHDNFGFDDLVR[166.11].D sp|O00165|HAX1_HUMAN 1 1490.6818 1.37 54377 21394 3 1490.680909 497.9012 HCLS1-associated protein X-1 OS=Homo sapiens OX=9606 GN=HAX1 PE=1 SV=2 4.41 3453.8 - 226901 - - - -0.5964 - 2.188 0.536 - 103.7 1 2 0 -0.0009 12 0 0 0 2.65E+06 1.94E+06 - - - 6.6859 1 221125_WJC_METTL3_EV_vs_WT_F04.21395.21395.2 1.71E-10 30-Oct K.EEDAFHFVSYVPVNGR.L "sp|Q9Y5K5|UCHL5_HUMAN,tr|H0Y4E0|H0Y4E0_HUMAN,tr|Q5LJA9|Q5LJA9_HUMAN,tr|H0Y6Y4|H0Y6Y4_HUMAN,tr|Q5LJB0|Q5LJB0_HUMAN,tr|Q5LJA5|Q5LJA5_HUMAN" 6 1864.8744 0.28 54378 21395 2 1864.877377 933.4445 Ubiquitin carboxyl-terminal hydrolase isozyme L5 OS=Homo sapiens OX=9606 GN=UCHL5 PE=1 SV=3 4.65 3453.9 - 215414 - - - 1.5894 - 2.271 0.651 - 265.5 1 2 0 0.003 16 0 0 0 1.36E+06 4.80E+06 - - - 5.8649 1 221125_WJC_METTL3_EV_vs_WT_F04.21400.21400.4 6.80E-11 23/114 K.ILHVDNHIGISIAGLTADAR.L "sp|P25786|PSA1_HUMAN,tr|F5GX11|F5GX11_HUMAN,tr|B4DEV8|B4DEV8_HUMAN" 3 2085.1331 1.28 54381 21400 4 2085.12901 522.2905 Proteasome subunit alpha type-1 OS=Homo sapiens OX=9606 GN=PSMA1 PE=1 SV=1 5.98 3454.6 - 796811 - - - -1.9553 - 4.593 0.55 - 341.2 1 2 0 -0.0041 20 0 0 0 6.87E+06 5.36E+06 - - - 4.5218 1 221125_WJC_METTL3_EV_vs_WT_F04.21401.21401.4 8.85E-07 21/114 K.ILHVDNHIGISIAGLTADAR[166.11].L "sp|P25786|PSA1_HUMAN,tr|F5GX11|F5GX11_HUMAN,tr|B4DEV8|B4DEV8_HUMAN" 3 2095.1414 1.28 54382 21401 4 2095.142936 524.7926 Proteasome subunit alpha type-1 OS=Homo sapiens OX=9606 GN=PSMA1 PE=1 SV=1 5.98 3454.7 - 579260 - - - 0.7536 - 4.265 0.559 - 258.3 1 2 0 0.0016 20 0 0 0 6.87E+06 5.36E+06 - - - 4.576 0.9999 221125_WJC_METTL3_EV_vs_WT_F04.21407.21407.3 1.90E-06 Oct-44 K.DHIMEIFSTYGK[136.11].L "sp|Q15287|RNPS1_HUMAN,tr|H3BMM9|H3BMM9_HUMAN,tr|H3BV80|H3BV80_HUMAN,tr|H3BMS0|H3BMS0_HUMAN,tr|H3BTC0|H3BTC0_HUMAN" 5 1447.6897 1.7 54388 21407 3 1447.688237 483.5705 RNA-binding protein with serine-rich domain 1 OS=Homo sapiens OX=9606 GN=RNPS1 PE=1 SV=1 5.32 3455.5 - 151105 - - - -1.012 - 2.17 0.457 - 124.7 1 2 0 -0.0015 12 0 0 0 3.22E+06 1.90E+06 - - - 5.7821 0.9999 221125_WJC_METTL3_EV_vs_WT_F04.21412.21412.3 1.23E-07 19/76 R.YESSALPSGQLTSLSEYASR.M "sp|Q12931|TRAP1_HUMAN,tr|I3L0K7|I3L0K7_HUMAN" 2 2145.0226 1.34 54391 21412 3 2145.028116 716.0148 "Heat shock protein 75 kDa, mitochondrial OS=Homo sapiens OX=9606 GN=TRAP1 PE=1 SV=3" 4.53 3456.1 - 1.57E+06 - - - 2.5748 - 3.471 0.386 - 435.2 1 2 0 0.0055 20 0 0 0 9.82E+07 7.35E+07 - - - 5.861 0.9987 221125_WJC_METTL3_EV_vs_WT_F04.21413.21413.3 0.00984 Oct-56 K.TLNDMRQEYEQLIAK.N "sp|P35527|K1C9_HUMAN,tr|K7EQQ3|K7EQQ3_HUMAN" 2 1850.9196 -1 54392 21413 3 1850.922889 617.9805 "Keratin, type I cytoskeletal 9 OS=Homo sapiens OX=9606 GN=KRT9 PE=1 SV=3" 4.68 3456.2 - 799627 - - - 1.751 - 1.84 0.411 - 70.7 1 2 1 0.0032 15 0 0 0 0.00E+00 0.00E+00 - - - 4.7124 0.9999 221125_WJC_METTL3_EV_vs_WT_F04.21414.21414.2 0.000245 Nov-40 K.DYEEVGVDSVEGEGEEEGEEY.- "sp|Q71U36|TBA1A_HUMAN,sp|P68363|TBA1B_HUMAN" 2 2347.8976 - 54393 21414 2 2347.898614 1174.9561 Tubulin alpha-1A chain OS=Homo sapiens OX=9606 GN=TUBA1A PE=1 SV=1 3.18 3456.4 - 586194 - - - 0.4442 - 2.126 0.625 - 202.4 1 2 0 0.001 21 0 0 0 - - - - - 5.5113 0.9896 221125_WJC_METTL3_EV_vs_WT_F04.21418.21418.3 0.000375 13/60 L.RDYLHLPPEIVPATLR.R "sp|P46783|RS10_HUMAN,tr|A0A2R8Y6L3|A0A2R8Y6L3_HUMAN,tr|F6U211|F6U211_HUMAN,tr|A0A1W2PQS6|A0A1W2PQS6_HUMAN,tr|A0A2R8YFH6|A0A2R8YFH6_HUMAN,tr|A0A2R8Y7H1|A0A2R8Y7H1_HUMAN,tr|S4R435|S4R435_HUMAN" 7 1889.0523 0.99 54397 21418 3 1889.051426 630.6914 40S ribosomal protein S10 OS=Homo sapiens OX=9606 GN=RPS10 PE=1 SV=1 6.75 3456.9 - 431016 - - - -0.4717 - 2.648 0.373 - 236.9 1 1 0 -0.0009 16 0 0 0 1.25E+07 1.25E+07 - - - 5.197 1 221125_WJC_METTL3_EV_vs_WT_F04.21420.21420.3 6.20E-08 Oct-44 K.DHIMEIFSTYGK.L "sp|Q15287|RNPS1_HUMAN,tr|H3BMM9|H3BMM9_HUMAN,tr|H3BV80|H3BV80_HUMAN,tr|H3BMS0|H3BMS0_HUMAN,tr|H3BTC0|H3BTC0_HUMAN" 5 1439.6755 1.7 54399 21420 3 1439.678162 480.8991 RNA-binding protein with serine-rich domain 1 OS=Homo sapiens OX=9606 GN=RNPS1 PE=1 SV=1 5.32 3457.1 - 298363 - - - 1.8476 - 2.262 0.613 - 144.2 1 2 0 0.0027 12 0 0 0 3.22E+06 1.90E+06 - - - 7.6361 1 221125_WJC_METTL3_EV_vs_WT_F04.21426.21426.3 1.08E-06 13/48 R.K[136.11]VESLQEEIAFLK[136.11].K "sp|P08670|VIME_HUMAN,tr|B0YJC5|B0YJC5_HUMAN,tr|B0YJC4|B0YJC4_HUMAN" 3 1548.8734 1.96 54404 21426 3 1548.875233 517.2984 Vimentin OS=Homo sapiens OX=9606 GN=VIM PE=1 SV=4 4.79 3457.9 - 5.64E+06 - - - 1.177 - 3.173 0.577 - 370.2 1 2 0 0.0018 13 0 0 0 1.05E+08 5.38E+07 - - - 8.1031 1 221125_WJC_METTL3_EV_vs_WT_F04.21430.21430.2 1.68E-10 19/24 R.KVESLQEEIAFLK.K "sp|P08670|VIME_HUMAN,tr|B0YJC5|B0YJC5_HUMAN,tr|B0YJC4|B0YJC4_HUMAN" 3 1532.845 1.95 54408 21430 2 1532.84753 767.4298 Vimentin OS=Homo sapiens OX=9606 GN=VIM PE=1 SV=4 4.79 3458.2 - 1.39E+06 - - - 1.644 - 3.716 0.665 - 1039.3 1 2 0 0.0025 13 0 0 0 1.43E+07 7.31E+06 - - - 7.3208 1 221125_WJC_METTL3_EV_vs_WT_F04.21431.21431.2 2.33E-14 19/38 R.YESSALPSGQLTSLSEYASR.M "sp|Q12931|TRAP1_HUMAN,tr|I3L0K7|I3L0K7_HUMAN" 2 2145.0226 1.88 54409 21431 2 2145.024418 1073.5186 "Heat shock protein 75 kDa, mitochondrial OS=Homo sapiens OX=9606 GN=TRAP1 PE=1 SV=3" 4.53 3458.4 - 680792 - - - 0.8508 - 4.058 0.711 - 487.7 1 2 0 0.0018 20 0 0 0 2.28E+07 1.21E+07 - - - 7.7355 1 221125_WJC_METTL3_EV_vs_WT_F04.21433.21433.2 6.44E-10 15/28 L.TTDNANILLQIDNAR.L "sp|P13645|K1C10_HUMAN,tr|A0A1B0GVI3|A0A1B0GVI3_HUMAN" 2 1670.8588 999 54411 21433 2 1670.861319 836.4367 "Keratin, type I cytoskeletal 10 OS=Homo sapiens OX=9606 GN=KRT10 PE=1 SV=6" 4.21 3458.6 - 330080 - - - 1.5298 - 3.064 0.583 - 723.6 1 1 0 0.0026 15 0 0 0 3.49E+07 0.00E+00 - - - 6.0991 0.9976 221125_WJC_METTL3_EV_vs_WT_F04.21439.21439.3 0.00445 Aug-60 K.EEDAFHFVSYVPVNGR[166.11].L "sp|Q9Y5K5|UCHL5_HUMAN,tr|H0Y4E0|H0Y4E0_HUMAN,tr|Q5LJA9|Q5LJA9_HUMAN,tr|H0Y6Y4|H0Y6Y4_HUMAN,tr|Q5LJB0|Q5LJB0_HUMAN,tr|Q5LJA5|Q5LJA5_HUMAN" 6 1874.8827 1.63 54415 21439 3 1874.880467 625.9682 Ubiquitin carboxyl-terminal hydrolase isozyme L5 OS=Homo sapiens OX=9606 GN=UCHL5 PE=1 SV=3 4.65 3459.3 - 620367 - - - -1.1819 - 1.404 0.302 - 44.1 1 2 0 -0.0022 16 0 0 0 7.95E+07 4.88E+07 - - - 2.777 1 221125_WJC_METTL3_EV_vs_WT_F04.21441.21441.3 5.53E-14 22/64 K.VHYENNSPFLTITSMTR[166.11].V "sp|P04843|RPN1_HUMAN,tr|B7Z4L4|B7Z4L4_HUMAN" 2 2018.9759 1.05 54417 21441 3 2018.976275 673.9993 Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit 1 OS=Homo sapiens OX=9606 GN=RPN1 PE=1 SV=1 6.72 3459.5 - 1.81E+06 - - - 0.1704 - 3.647 0.703 - 759.3 1 2 0 0.0003 17 0 0 0 4.40E+07 4.18E+07 - - - 9.6465 1 221125_WJC_METTL3_EV_vs_WT_F04.21442.21442.3 3.96E-10 20/88 K.QGEYGLASIC[160.03]NGGGGASAMLIQK.L "sp|P24752|THIL_HUMAN,tr|A0A5F9ZHD4|A0A5F9ZHD4_HUMAN,tr|A0A5F9ZHJ0|A0A5F9ZHJ0_HUMAN,tr|A0A5F9ZHL1|A0A5F9ZHL1_HUMAN,tr|A0A5F9ZI66|A0A5F9ZI66_HUMAN" 5 2281.0831 1.35 54418 21442 3 2281.084588 761.3683 "Acetyl-CoA acetyltransferase, mitochondrial OS=Homo sapiens OX=9606 GN=ACAT1 PE=1 SV=1" 5.99 3459.6 - 1.09E+06 - - - 0.6514 - 3.862 0.629 - 537.5 1 2 0 0.0015 23 0 0 0 4.52E+07 3.36E+07 - - - 8.7221 0.9999 221125_WJC_METTL3_EV_vs_WT_F04.21444.21444.4 8.06E-07 21/114 K.IALLNVELELK[136.11]AEK[136.11]DNAEIR[166.11].V sp|Q99832|TCPH_HUMAN 1 2306.3056 0.18 54420 21444 4 2306.306712 577.5837 T-complex protein 1 subunit eta OS=Homo sapiens OX=9606 GN=CCT7 PE=1 SV=2 4.59 3459.8 - 861958 - - - 0.49 - 3.132 0.512 - 370.5 1 2 2 0.0011 20 0 0 0 4.32E+05 2.42E+06 - - - 4.0638 1 221125_WJC_METTL3_EV_vs_WT_F04.21446.21446.2 7.82E-15 18/38 R.YESSALPSGQLTSLSEYASR[166.11].M "sp|Q12931|TRAP1_HUMAN,tr|I3L0K7|I3L0K7_HUMAN" 2 2155.0309 1.88 54422 21446 2 2155.034691 1078.5227 "Heat shock protein 75 kDa, mitochondrial OS=Homo sapiens OX=9606 GN=TRAP1 PE=1 SV=3" 4.53 3460.1 - 700136 - - - 1.7763 - 4.107 0.681 - 472.4 1 2 0 0.0038 20 0 0 0 2.28E+07 1.21E+07 - - - 7.5428 0.9999 221125_WJC_METTL3_EV_vs_WT_F04.21448.21448.3 8.79E-08 Dec-44 K.SKDWVFLNYTYK.R sp|Q9Y2H1|ST38L_HUMAN 1 1562.7769 9.06 54424 21448 3 1562.776566 521.9329 Serine\threonine-protein kinase 38-like OS=Homo sapiens OX=9606 GN=STK38L PE=1 SV=3 8.15 3460.3 - 684300 - - - -0.2329 - 2.601 0.537 - 172.7 1 2 1 -0.0004 12 0 0 0 7.10E+06 7.84E+05 - - - 7.1765 0.996 221125_WJC_METTL3_EV_vs_WT_F04.21450.21450.3 2.42E-08 16/56 L.TTDNANILLQIDNAR.L "sp|P13645|K1C10_HUMAN,tr|A0A1B0GVI3|A0A1B0GVI3_HUMAN" 2 1670.8588 5.07 54426 21450 3 1670.859289 557.9602 "Keratin, type I cytoskeletal 10 OS=Homo sapiens OX=9606 GN=KRT10 PE=1 SV=6" 4.21 3460.6 - 568942 - - - 0.3148 - 2.666 0.459 - 455.8 1 1 0 0.0005 15 0 0 0 2.26E+07 4.45E+06 - - - 6.2159 0.9999 221125_WJC_METTL3_EV_vs_WT_F04.21451.21451.3 3.85E-07 13/44 K.VQK[136.11]LLQDFFNGR[166.11].D "sp|P0DMV8|HS71A_HUMAN,sp|P0DMV9|HS71B_HUMAN,tr|V9GZ37|V9GZ37_HUMAN,tr|A0A0G2JIW1|A0A0G2JIW1_HUMAN" 4 1481.811 0.02 54427 21451 3 1481.810992 494.9443 Heat shock 70 kDa protein 1A OS=Homo sapiens OX=9606 GN=HSPA1A PE=1 SV=1 8.72 3460.7 - 430649 - - - 0.0162 - 2.543 0.535 - 259.8 1 2 1 0 12 0 0 0 1.25E+05 5.15E+06 - - - 7.0918 1 221125_WJC_METTL3_EV_vs_WT_F04.21453.21453.2 2.98E-11 13/30 R.SSSFSSWDDSSDSYWK[136.11].K sp|Q9NP61|ARFG3_HUMAN 1 1877.7472 1.01 54429 21453 2 1877.745793 939.8809 ADP-ribosylation factor GTPase-activating protein 3 OS=Homo sapiens OX=9606 GN=ARFGAP3 PE=1 SV=1 3.93 3460.9 - 275451 - - - -0.7243 - 2.839 0.702 - 509.1 1 2 0 -0.0014 16 0 0 0 1.87E+07 1.85E+07 - - - 6.7909 1 221125_WJC_METTL3_EV_vs_WT_F04.21457.21457.3 2.66E-15 25/80 K.TAEELMNFSK[136.11]GEENLMDAQVK[136.11].A "sp|P50990|TCPQ_HUMAN,tr|H7C4C8|H7C4C8_HUMAN" 2 2399.132 0.35 54431 21457 3 2399.130089 800.7179 T-complex protein 1 subunit theta OS=Homo sapiens OX=9606 GN=CCT8 PE=1 SV=4 4.25 3461.5 - 4.13E+06 - - - -0.7807 - 4.834 0.698 - 780.3 1 2 1 -0.0019 21 0 0 0 5.27E+07 1.52E+08 - - - 10.0991 1 221125_WJC_METTL3_EV_vs_WT_F04.21458.21458.3 1.17E-10 20/88 K.QGEYGLASIC[160.03]NGGGGASAMLIQK[136.11].L "sp|P24752|THIL_HUMAN,tr|A0A5F9ZHD4|A0A5F9ZHD4_HUMAN,tr|A0A5F9ZHJ0|A0A5F9ZHJ0_HUMAN,tr|A0A5F9ZHL1|A0A5F9ZHL1_HUMAN,tr|A0A5F9ZI66|A0A5F9ZI66_HUMAN" 5 2289.0973 1.35 54432 21458 3 2289.099797 764.0397 "Acetyl-CoA acetyltransferase, mitochondrial OS=Homo sapiens OX=9606 GN=ACAT1 PE=1 SV=1" 5.99 3461.6 - 2.95E+06 - - - 1.0899 - 3.519 0.668 - 410.9 1 2 0 0.0025 23 0 0 0 4.52E+07 3.36E+07 - - - 8.9385 0.9989 221125_WJC_METTL3_EV_vs_WT_F04.21459.21459.2 0.000827 17/28 K.TLNDMRQEYEQLIAK.N "sp|P35527|K1C9_HUMAN,tr|K7EQQ3|K7EQQ3_HUMAN" 2 1850.9196 999 54433 21459 2 1850.918637 926.4671 "Keratin, type I cytoskeletal 9 OS=Homo sapiens OX=9606 GN=KRT9 PE=1 SV=3" 4.68 3461.7 - 2.18E+06 - - - -0.5462 - 2.874 0.507 - 828.8 1 2 1 -0.001 15 0 0 0 9.42E+07 0.00E+00 - - - 5.3809 1 221125_WJC_METTL3_EV_vs_WT_F04.21461.21461.2 3.93E-07 20/32 R.VEAVNMAEGIIHDTETK[136.11].M "sp|P38646|GRP75_HUMAN,tr|A0A7I2V2S7|A0A7I2V2S7_HUMAN,tr|A0A7I2V2G2|A0A7I2V2G2_HUMAN,tr|A0A7I2V3F7|A0A7I2V3F7_HUMAN,tr|A0A7I2YQB2|A0A7I2YQB2_HUMAN,tr|D6RCD7|D6RCD7_HUMAN" 6 1863.9128 0.4 54435 21461 2 1863.912176 932.9637 "Stress-70 protein, mitochondrial OS=Homo sapiens OX=9606 GN=HSPA9 PE=1 SV=2" 4.4 3461.9 - 1.56E+06 - - - -0.323 - 4.011 0.642 - 967.2 1 2 0 -0.0006 17 0 0 0 2.47E+07 6.13E+07 - - - 7.1976 1 221125_WJC_METTL3_EV_vs_WT_F04.21464.21464.4 0.000135 23/114 R.TPLHMAASEGHASIVEVLLK.H "sp|Q06547|GABP1_HUMAN,tr|H9ZYI9|H9ZYI9_HUMAN" 2 2102.1194 3.17 54438 21464 4 2102.116409 526.5371 GA-binding protein subunit beta-1 OS=Homo sapiens OX=9606 GN=GABPB1 PE=1 SV=2 5.94 3462.3 - 920734 - - - -1.4281 - 4.577 0.555 - 392 1 2 0 -0.003 20 0 0 0 6.24E+06 1.97E+06 - - - 4.5644 0.9833 221125_WJC_METTL3_EV_vs_WT_F04.21466.21466.3 5.84E-06 Dec-56 K.AKGPVTIPYPLFQSH.V "sp|P78347|GTF2I_HUMAN,tr|A0A494C1K3|A0A494C1K3_HUMAN" 2 1653.8879 1.43 54440 21466 3 1653.88859 552.3032 General transcription factor II-I OS=Homo sapiens OX=9606 GN=GTF2I PE=1 SV=2 8.64 3462.5 - 622167 - - - 0.4305 - 2.71 0.464 - 205.6 1 1 1 0.0007 15 0 0 0 2.47E+07 1.72E+07 - - - 6.3143 0.9999 221125_WJC_METTL3_EV_vs_WT_F04.21467.21467.4 3.00E-06 14/114 R.TPLHMAASEGHASIVEVLLK[136.11].H "sp|Q06547|GABP1_HUMAN,tr|H9ZYI9|H9ZYI9_HUMAN" 2 2110.1336 3.26 54441 21467 4 2110.134164 528.5407 GA-binding protein subunit beta-1 OS=Homo sapiens OX=9606 GN=GABPB1 PE=1 SV=2 5.94 3462.7 - 429694 - - - 0.2621 - 2.716 0.446 - 66.4 1 2 0 0.0006 20 0 0 0 6.42E+06 1.97E+06 - - - 3.4419 1 221125_WJC_METTL3_EV_vs_WT_F04.21470.21470.3 5.17E-15 24/80 K.TAEELMNFSKGEENLMDAQVK.A "sp|P50990|TCPQ_HUMAN,tr|H7C4C8|H7C4C8_HUMAN" 2 2383.1036 0.36 54442 21470 3 2383.099119 795.3751 T-complex protein 1 subunit theta OS=Homo sapiens OX=9606 GN=CCT8 PE=1 SV=4 4.25 3463.1 - 2.14E+06 - - - -1.8644 - 4.232 0.699 - 667.8 1 2 1 -0.0044 21 0 0 0 5.44E+07 1.52E+08 - - - 9.7907 0.9998 221125_WJC_METTL3_EV_vs_WT_F04.21471.21471.2 3.90E-06 22-Dec K.DAGTIAGLNVLR.L "sp|P11142|HSP7C_HUMAN,tr|E9PQQ4|E9PQQ4_HUMAN,tr|E9PKE3|E9PKE3_HUMAN,tr|E9PN89|E9PN89_HUMAN,tr|E9PLF4|E9PLF4_HUMAN,tr|E9PI65|E9PI65_HUMAN,tr|E9PK54|E9PK54_HUMAN,tr|E9PQK7|E9PQK7_HUMAN" 8 1198.667 0.65 54443 21471 2 1198.666236 600.3408 Heat shock cognate 71 kDa protein OS=Homo sapiens OX=9606 GN=HSPA8 PE=1 SV=1 5.84 3463.2 - 2.08E+06 - - - -0.6257 - 2.411 0.418 - 438.2 1 2 0 -0.0008 12 0 0 0 2.92E+07 4.51E+07 - - - 4.4437 1 221125_WJC_METTL3_EV_vs_WT_F04.21472.21472.2 8.31E-10 14/30 R.SSSFSSWDDSSDSYWK.K sp|Q9NP61|ARFG3_HUMAN 1 1869.733 1.01 54444 21472 2 1869.732956 935.8738 ADP-ribosylation factor GTPase-activating protein 3 OS=Homo sapiens OX=9606 GN=ARFGAP3 PE=1 SV=1 3.93 3463.3 - 1.25E+06 - - - 0.0016 - 3.091 0.661 - 688.1 1 2 0 0 16 0 0 0 1.87E+07 1.85E+07 - - - 6.6976 1 221125_WJC_METTL3_EV_vs_WT_F04.21474.21474.2 3.55E-07 17/32 R.VEAVNMAEGIIHDTETK.M "sp|P38646|GRP75_HUMAN,tr|A0A7I2V2S7|A0A7I2V2S7_HUMAN,tr|A0A7I2V2G2|A0A7I2V2G2_HUMAN,tr|A0A7I2V3F7|A0A7I2V3F7_HUMAN,tr|A0A7I2YQB2|A0A7I2YQB2_HUMAN,tr|D6RCD7|D6RCD7_HUMAN" 6 1855.8986 0.4 54446 21474 2 1855.896323 928.9566 "Stress-70 protein, mitochondrial OS=Homo sapiens OX=9606 GN=HSPA9 PE=1 SV=2" 4.4 3463.6 - 924019 - - - -1.215 - 3.938 0.622 - 930.4 1 2 0 -0.0023 17 0 0 0 2.47E+07 6.13E+07 - - - 7.0042 0.995 221125_WJC_METTL3_EV_vs_WT_F04.21478.21478.3 0.000103 18/60 W.GNVGFVFTKEDLTEIR.D "sp|Q8NHW5|RLA0L_HUMAN,sp|P05388|RLA0_HUMAN,tr|G3V210|G3V210_HUMAN,tr|F8VU65|F8VU65_HUMAN,tr|F8VWV4|F8VWV4_HUMAN,tr|F8VWS0|F8VWS0_HUMAN,tr|F8VS58|F8VS58_HUMAN,tr|F8VW21|F8VW21_HUMAN,tr|F8VZS0|F8VZS0_HUMAN,tr|F8VRK7|F8VRK7_HUMAN,tr|F8VQY6|F8VQY6_HUMAN,tr|F8VPE8|F8VPE8_HUMAN" 12 1823.9418 0.19 54450 21478 3 1823.943364 608.9879 60S acidic ribosomal protein P0-like OS=Homo sapiens OX=9606 GN=RPLP0P6 PE=5 SV=1 4.68 3464.1 - 451833 - - - 0.8772 - 3.69 0.574 - 479.1 1 1 1 0.0016 16 0 0 0 3.64E+06 1.87E+07 - - - 8.2892 0.9997 221125_WJC_METTL3_EV_vs_WT_F04.21479.21479.4 0.0142 11/108 K.AVEYYFASDASAVIEHTNR[166.11].V "sp|Q06210|GFPT1_HUMAN,tr|A0A6I8PRN4|A0A6I8PRN4_HUMAN,tr|A0A6I8PTT9|A0A6I8PTT9_HUMAN" 3 2152.0101 0.87 54451 21479 4 2152.013518 539.0098 Glutamine--fructose-6-phosphate aminotransferase [isomerizing] 1 OS=Homo sapiens OX=9606 GN=GFPT1 PE=1 SV=3 4.65 3464.2 - 296614 - - - 1.6032 - 2.154 0.376 - 85.4 1 2 0 0.0034 19 0 0 0 9.23E+05 1.06E+06 - - - 2.7573 0.9999 221125_WJC_METTL3_EV_vs_WT_F04.21482.21482.2 0.000106 13/22 K.DAGTIAGLNVLR[166.11].L "sp|P11142|HSP7C_HUMAN,tr|E9PQQ4|E9PQQ4_HUMAN,tr|E9PKE3|E9PKE3_HUMAN,tr|E9PN89|E9PN89_HUMAN,tr|E9PLF4|E9PLF4_HUMAN,tr|E9PI65|E9PI65_HUMAN,tr|E9PK54|E9PK54_HUMAN,tr|E9PQK7|E9PQK7_HUMAN" 8 1208.6753 0.65 54452 21482 2 1208.674699 605.3449 Heat shock cognate 71 kDa protein OS=Homo sapiens OX=9606 GN=HSPA8 PE=1 SV=1 5.84 3464.6 - 3.04E+06 - - - -0.4608 - 2.526 0.51 - 624.7 1 2 0 -0.0006 12 0 0 0 2.92E+07 4.51E+07 - - - 5.2458 1 221125_WJC_METTL3_EV_vs_WT_F04.21486.21486.2 1.23E-14 18/34 K.SQESQEADEQLVAEVVEK.C "sp|O75410|TACC1_HUMAN,tr|E5RFM9|E5RFM9_HUMAN,tr|R4GMT7|R4GMT7_HUMAN,tr|E5RJG6|E5RJG6_HUMAN" 4 2016.9488 1.54 54456 21486 2 2016.948309 1009.4817 Transforming acidic coiled-coil-containing protein 1 OS=Homo sapiens OX=9606 GN=TACC1 PE=1 SV=2 3.83 3465.1 - 516204 - - - -0.2231 - 3.663 0.737 - 880.4 1 2 0 -0.0004 18 0 0 0 1.58E+07 1.02E+07 - - - 7.6762 0.9946 221125_WJC_METTL3_EV_vs_WT_F04.21488.21488.4 0.18 Dec-90 R.NVPTDVLSFPFHEHLK[136.11].A sp|P58557|YBEY_HUMAN 1 1886.977 1.13 54458 21488 4 1886.97722 472.7515 Endoribonuclease YbeY OS=Homo sapiens OX=9606 GN=YBEY PE=1 SV=2 5.99 3465.3 - 443878 - - - 0.0986 - 1.802 0.225 - 118.3 1 2 0 0.0002 16 0 0 0 8.04E+06 7.13E+06 - - - 1.3918 0.998 221125_WJC_METTL3_EV_vs_WT_F04.21491.21491.3 0.000331 13/80 R.YAFGQETNVPLNNFSADQVTR.A sp|O43678|NDUA2_HUMAN 1 2370.124 6.73 54459 21491 3 2370.115227 791.0486 NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 2 OS=Homo sapiens OX=9606 GN=NDUFA2 PE=1 SV=3 4.37 3465.7 - 1.76E+06 - - - -3.7175 - 2.02 0.357 - 109.6 1 2 0 -0.0088 21 0 0 0 1.61E+08 2.40E+07 - - - 4.2034 1 221125_WJC_METTL3_EV_vs_WT_F04.21493.21493.3 7.03E-06 14/52 R.DNNGVIGLLEPMK[136.11]K[136.11].S "sp|P18754|RCC1_HUMAN,tr|C9JQZ4|C9JQZ4_HUMAN,tr|C9J3R0|C9J3R0_HUMAN,tr|C9JMJ4|C9JMJ4_HUMAN,tr|C9JW69|C9JW69_HUMAN,tr|C9JRH2|C9JRH2_HUMAN" 6 1542.8411 0.7 54461 21493 3 1542.839232 515.2876 Regulator of chromosome condensation OS=Homo sapiens OX=9606 GN=RCC1 PE=1 SV=1 6.07 3465.9 - 922800 - - - -1.1874 - 2.504 0.539 - 298.2 1 2 0 -0.0018 14 0 0 0 8.46E+06 1.21E+07 - - - 6.9881 0.9998 221125_WJC_METTL3_EV_vs_WT_F04.21505.21505.3 2.40E-05 Dec-52 R.DNNGVIGLLEPMKK.S "sp|P18754|RCC1_HUMAN,tr|C9JQZ4|C9JQZ4_HUMAN,tr|C9J3R0|C9J3R0_HUMAN,tr|C9JMJ4|C9JMJ4_HUMAN,tr|C9JW69|C9JW69_HUMAN,tr|C9JRH2|C9JRH2_HUMAN" 6 1526.8127 0.23 54469 21505 3 1526.812879 509.9448 Regulator of chromosome condensation OS=Homo sapiens OX=9606 GN=RCC1 PE=1 SV=1 6.07 3467.4 - 639363 - - - 0.1408 - 2.295 0.349 - 209.2 1 2 0 0.0002 14 0 0 0 1.11E+07 4.83E+07 - - - 4.6386 1 221125_WJC_METTL3_EV_vs_WT_F04.21507.21507.3 3.77E-10 17/84 K.GPAVGIDLGTTYSC[160.03]VGVFQHGK[136.11].V "sp|P11142|HSP7C_HUMAN,tr|E9PQQ4|E9PQQ4_HUMAN,tr|E9PNE6|E9PNE6_HUMAN,tr|E9PKE3|E9PKE3_HUMAN,tr|E9PLF4|E9PLF4_HUMAN,tr|E9PI65|E9PI65_HUMAN,tr|E9PK54|E9PK54_HUMAN,tr|E9PN25|E9PN25_HUMAN,tr|E9PPY6|E9PPY6_HUMAN,tr|E9PQK7|E9PQK7_HUMAN" 10 2270.1245 1.68 54471 21507 3 2270.124096 757.7154 Heat shock cognate 71 kDa protein OS=Homo sapiens OX=9606 GN=HSPA8 PE=1 SV=1 6.73 3467.7 - 740827 - - - -0.1793 - 2.986 0.61 - 243.7 1 2 0 -0.0004 22 0 0 0 1.29E+08 7.71E+07 - - - 7.9343 1 221125_WJC_METTL3_EV_vs_WT_F04.21509.21509.3 1.26E-05 16/52 K.EHVEEISELFYDAK.S "sp|Q9Y265|RUVB1_HUMAN,tr|H7C4G5|H7C4G5_HUMAN" 2 1707.7992 0.77 54473 21509 3 1707.803242 570.2737 RuvB-like 1 OS=Homo sapiens OX=9606 GN=RUVBL1 PE=1 SV=1 4.25 3468 - 478447 - - - 2.3773 - 3.326 0.598 - 386.1 1 2 0 0.0041 14 0 0 0 2.20E+07 2.86E+07 - - - 8.3997 0.9984 221125_WJC_METTL3_EV_vs_WT_F04.21516.21516.3 1.09E-06 19/96 S.TNPAPGILGPPPPSFHLGGPAVGPR[166.11].G "sp|P43243|MATR3_HUMAN,tr|D6RE02|D6RE02_HUMAN,tr|B3KM87|B3KM87_HUMAN,tr|A8MXP9|A8MXP9_HUMAN,tr|D6RAY2|D6RAY2_HUMAN,tr|D6R991|D6R991_HUMAN,tr|A0A0R4J2E8|A0A0R4J2E8_HUMAN,tr|D6RAM9|D6RAM9_HUMAN,tr|D6RIA2|D6RIA2_HUMAN,tr|H0Y8T4|H0Y8T4_HUMAN,tr|D6REM6|D6REM6_HUMAN,tr|D6RBI2|D6RBI2_HUMAN" 12 2412.2942 0.72 54478 21516 3 2412.291786 805.1053 Matrin-3 OS=Homo sapiens OX=9606 GN=MATR3 PE=1 SV=2 9.44 3468.7 - 1.32E+06 - - - -0.9879 - 3.246 0.559 - 270.8 1 1 0 -0.0024 25 0 0 0 1.91E+07 2.67E+07 - - - 7.4805 1 221125_WJC_METTL3_EV_vs_WT_F04.21517.21517.3 4.38E-12 19/80 R.GHFEAFGTLTDC[160.03]VVVVNPQTK.R sp|Q13151|ROA0_HUMAN 1 2318.1365 5.06 54479 21517 3 2318.135302 773.7194 Heterogeneous nuclear ribonucleoprotein A0 OS=Homo sapiens OX=9606 GN=HNRNPA0 PE=1 SV=1 5.32 3468.9 - 1.14E+06 - - - -0.5246 - 3.521 0.648 - 371.2 1 2 0 -0.0012 21 0 0 0 3.68E+08 7.28E+07 - - - 8.782 1 221125_WJC_METTL3_EV_vs_WT_F04.21520.21520.3 9.43E-08 14/44 K.WELLQQVDTSTR.T sp|P04264|K2C1_HUMAN 1 1474.7416 223.6 54482 21520 3 1474.739715 492.5878 "Keratin, type II cytoskeletal 1 OS=Homo sapiens OX=9606 GN=KRT1 PE=1 SV=6" 4.37 3469.3 - 584791 - - - -1.2829 - 2.729 0.448 - 390.6 1 2 0 -0.0019 12 0 0 0 2.20E+07 9.84E+04 - - - 6.317 0.8466 221125_WJC_METTL3_EV_vs_WT_F04.21526.21526.3 1.60E-07 14/76 K.GNPQGFNQGLDC[160.03]DVIVAEVR.S sp|Q86U44|MTA70_HUMAN 1 2187.0379 0.15 54486 21526 3 2189.03545 730.0199 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 4.03 3470 - 4.89E+06 - - - 913.3742 - 2.441 0.612 - 198.6 1 2 0 1.9976 20 0 0 0 7.22E+07 4.96E+08 - - - 6.9749 0.8552 221125_WJC_METTL3_EV_vs_WT_F04.21528.21528.3 7.80E-07 16/64 L.GNQLDGIHLLDPDVVAR[166.11].F sp|Q86U44|MTA70_HUMAN 1 1840.9671 0.08 54488 21528 3 1841.965144 614.663 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 4.41 3470.1 - 2.76E+06 - - - 542.1406 - 3.179 0.555 - 247.1 1 1 0 0.9981 17 0 0 0 3.94E+07 5.00E+08 - - - 7.3731 1 221125_WJC_METTL3_EV_vs_WT_F04.21529.21529.3 9.76E-09 20/80 R.GHFEAFGTLTDC[160.03]VVVVNPQTK[136.11].R sp|Q13151|ROA0_HUMAN 1 2326.1507 1.2 54489 21529 3 2326.153002 776.3908 Heterogeneous nuclear ribonucleoprotein A0 OS=Homo sapiens OX=9606 GN=HNRNPA0 PE=1 SV=1 5.32 3470.2 - 1.08E+06 - - - 0.9819 - 3.668 0.651 - 400.1 1 2 0 0.0023 21 0 0 0 1.95E+07 1.63E+07 - - - 8.9132 1 221125_WJC_METTL3_EV_vs_WT_F04.21530.21530.2 5.46E-11 17/28 R.LDVGNFSWGSEC[160.03]C[160.03]TR[166.11].K sp|P62241|RS8_HUMAN 1 1796.7486 0.59 54490 21530 2 1796.749482 899.3816 40S ribosomal protein S8 OS=Homo sapiens OX=9606 GN=RPS8 PE=1 SV=2 4.37 3470.4 - 874850 - - - 0.5054 - 3.191 0.703 - 1051.4 1 2 0 0.0009 15 0 0 0 4.52E+07 7.71E+07 - - - 7.0858 1 221125_WJC_METTL3_EV_vs_WT_F04.21532.21532.2 6.42E-11 14/34 R.TGLTSGNVTENLQTYIDK.S sp|Q9H8K7|PAAT_HUMAN 1 1952.9691 999 54492 21532 2 1952.965666 977.4918 ATPase PAAT OS=Homo sapiens OX=9606 GN=PAAT PE=1 SV=2 4.37 3470.6 - 395668 - - - -1.7589 - 3.209 0.653 - 533.5 1 2 0 -0.0034 18 0 0 0 1.65E+07 0.00E+00 - - - 6.7295 1 221125_WJC_METTL3_EV_vs_WT_F04.21536.21536.3 1.69E-06 24/68 K.HYFQNTQGLIFVVDSNDR.E "sp|P18085|ARF4_HUMAN,sp|P84077|ARF1_HUMAN,sp|P61204|ARF3_HUMAN,sp|P84085|ARF5_HUMAN,tr|F5H423|F5H423_HUMAN,tr|C9J1Z8|C9J1Z8_HUMAN,tr|C9JPM4|C9JPM4_HUMAN,tr|C9JAK5|C9JAK5_HUMAN,tr|F5H0C7|F5H0C7_HUMAN" 9 2152.0338 1.94 54494 21536 3 2152.034495 718.3519 ADP-ribosylation factor 4 OS=Homo sapiens OX=9606 GN=ARF4 PE=1 SV=3 5.21 3471.2 - 6.40E+06 - - - 0.3383 - 4.362 0.674 - 1078.1 1 2 0 0.0007 18 0 0 0 1.60E+08 8.25E+07 - - - 9.722 1 221125_WJC_METTL3_EV_vs_WT_F04.21539.21539.3 2.04E-06 16/52 K.EHVEEISELFYDAK[136.11].S "sp|Q9Y265|RUVB1_HUMAN,tr|H7C4G5|H7C4G5_HUMAN" 2 1715.8134 0.82 54497 21539 3 1715.810533 572.9451 RuvB-like 1 OS=Homo sapiens OX=9606 GN=RUVBL1 PE=1 SV=1 4.25 3471.4 - 1.39E+06 - - - -1.6604 - 3.327 0.569 - 514.2 1 2 0 -0.0028 14 0 0 0 2.33E+07 2.86E+07 - - - 8.0775 0.9998 221125_WJC_METTL3_EV_vs_WT_F04.21542.21542.2 1.22E-07 15/36 R.ADDLLPLGDQTQDGDFGSR.L sp|O43290|SNUT1_HUMAN 1 2018.9181 2.95 54498 21542 2 2018.913808 1010.4663 U4\U6.U5 tri-snRNP-associated protein 1 OS=Homo sapiens OX=9606 GN=SART1 PE=1 SV=1 3.66 3471.8 - 1.44E+06 - - - -2.1398 - 2.596 0.574 - 460.2 1 2 0 -0.0043 19 0 0 0 2.57E+07 8.68E+06 - - - 5.6246 1 221125_WJC_METTL3_EV_vs_WT_F04.21543.21543.2 1.50E-09 18/28 R.LDVGNFSWGSEC[160.03]C[160.03]TR.K sp|P62241|RS8_HUMAN 1 1786.7403 0.59 54499 21543 2 1786.738151 894.3774 40S ribosomal protein S8 OS=Homo sapiens OX=9606 GN=RPS8 PE=1 SV=2 4.37 3471.9 - 1.38E+06 - - - -1.205 - 3.397 0.718 - 1041.2 1 2 0 -0.0022 15 0 0 0 4.52E+07 7.71E+07 - - - 7.35 1 221125_WJC_METTL3_EV_vs_WT_F04.21544.21544.3 2.10E-09 16/76 K.MWDLSSNQAIQIAQHDAPVK.T "sp|P78406|RAE1L_HUMAN,tr|B0QZ36|B0QZ36_HUMAN,tr|E9PQ57|E9PQ57_HUMAN,tr|E9PPG9|E9PPG9_HUMAN" 4 2251.1056 1.67 54500 21544 3 2251.101737 751.3758 mRNA export factor OS=Homo sapiens OX=9606 GN=RAE1 PE=1 SV=1 5.19 3472 - 1.03E+07 - - - -1.6947 - 2.649 0.555 - 281.7 1 2 0 -0.0038 20 0 0 0 3.24E+08 1.95E+08 - - - 7.09 1 221125_WJC_METTL3_EV_vs_WT_F04.21555.21555.3 1.41E-11 17/72 R.ADDLLPLGDQTQDGDFGSR.L sp|O43290|SNUT1_HUMAN 1 2018.9181 2.74 54509 21555 3 2018.916394 673.98 U4\U6.U5 tri-snRNP-associated protein 1 OS=Homo sapiens OX=9606 GN=SART1 PE=1 SV=1 3.66 3473.3 - 2.68E+06 - - - -0.8589 - 3.231 0.638 - 330 1 2 0 -0.0017 19 0 0 0 3.62E+07 1.32E+07 - - - 8.5339 1 221125_WJC_METTL3_EV_vs_WT_F04.21556.21556.3 9.54E-09 18/80 R.YAFGQETNVPLNNFSADQVTR[166.11].A sp|O43678|NDUA2_HUMAN 1 2380.1323 6.68 54510 21556 3 2380.124649 794.3847 NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 2 OS=Homo sapiens OX=9606 GN=NDUFA2 PE=1 SV=3 4.37 3473.4 - 2.14E+06 - - - -3.2179 - 3.314 0.593 - 127.7 1 2 0 -0.0077 21 0 0 0 1.46E+08 2.19E+07 - - - 8.0218 0.9988 221125_WJC_METTL3_EV_vs_WT_F04.21559.21559.3 4.44E-07 20/52 Q.LDGIHLLDPDVVAR[166.11].F sp|Q86U44|MTA70_HUMAN 1 1541.8441 0.3 54513 21559 3 1541.843467 514.9553 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 4.41 3473.7 - 1.34E+06 - - - -0.4183 - 3.489 0.549 - 614.6 1 1 0 -0.0006 14 0 0 0 3.43E+07 1.14E+08 - - - 7.9815 1 221125_WJC_METTL3_EV_vs_WT_F04.21562.21562.3 2.88E-09 20/72 K.ESSHSGVVLSVEEVEAGLK[136.11].G "sp|Q9NRA8|4ET_HUMAN,tr|B1AKL4|B1AKL4_HUMAN,tr|B0QYZ7|B0QYZ7_HUMAN" 3 1962.999 1.15 54514 21562 3 1962.997522 655.3403 Eukaryotic translation initiation factor 4E transporter OS=Homo sapiens OX=9606 GN=EIF4ENIF1 PE=1 SV=2 4.48 3474.1 - 2.59E+06 - - - -0.728 - 3.445 0.617 - 673.5 1 2 0 -0.0014 19 0 0 0 7.04E+07 6.14E+07 - - - 8.4574 0.9999 221125_WJC_METTL3_EV_vs_WT_F04.21563.21563.3 5.98E-10 18/44 K.QAYVDK[136.11]LEELMK[136.11].L "sp|Q92598|HS105_HUMAN,tr|A0A0A0MSM0|A0A0A0MSM0_HUMAN" 2 1481.7771 0.07 54515 21563 3 1481.774175 494.933 Heat shock protein 105 kDa OS=Homo sapiens OX=9606 GN=HSPH1 PE=1 SV=1 4.68 3474.2 - 1.39E+06 - - - -1.9517 - 3.071 0.577 - 414 1 2 1 -0.0029 12 0 0 0 6.72E+06 9.40E+07 - - - 8.0822 1 221125_WJC_METTL3_EV_vs_WT_F04.21566.21566.2 2.93E-09 Dec-32 R.AETEC[160.03]QNTEYQQLLDIK.L "sp|P13645|K1C10_HUMAN,tr|A0A1B0GVI3|A0A1B0GVI3_HUMAN" 2 2081.9576 -1 54518 21566 2 2082.945512 1041.9861 "Keratin, type I cytoskeletal 10 OS=Homo sapiens OX=9606 GN=KRT10 PE=1 SV=6" 4 3474.6 - 538328 - - - 474.5351 - 2.887 0.666 - 528.8 1 2 0 0.988 17 0 0 0 0.00E+00 0.00E+00 - - - 6.2565 1 221125_WJC_METTL3_EV_vs_WT_F04.21572.21572.3 4.17E-07 15/52 K.VSHLLGINVTDFTR[166.11].G sp|P35579|MYH9_HUMAN 1 1580.855 0.92 54521 21572 3 1580.851988 527.9589 Myosin-9 OS=Homo sapiens OX=9606 GN=MYH9 PE=1 SV=4 6.71 3475.2 - 502674 - - - -1.9123 - 2.766 0.556 - 383 1 2 0 -0.003 14 0 0 0 1.64E+07 1.78E+07 - - - 7.4418 1 221125_WJC_METTL3_EV_vs_WT_F04.21574.21574.3 9.72E-07 13/52 K.VSHLLGINVTDFTR.G sp|P35579|MYH9_HUMAN 1 1570.8467 0.92 54523 21574 3 1570.843369 524.6229 Myosin-9 OS=Homo sapiens OX=9606 GN=MYH9 PE=1 SV=4 6.71 3475.5 - 565789 - - - -2.1466 - 2.346 0.556 - 309 1 2 0 -0.0034 14 0 0 0 1.64E+07 1.78E+07 - - - 7.004 0.9996 221125_WJC_METTL3_EV_vs_WT_F04.21575.21575.3 0.0249 Aug-56 R.LDVGNFSWGSEC[160.03]C[160.03]TR[166.11].K sp|P62241|RS8_HUMAN 1 1796.7486 1.08 54524 21575 3 1796.748653 599.9235 40S ribosomal protein S8 OS=Homo sapiens OX=9606 GN=RPS8 PE=1 SV=2 4.37 3475.6 - 497564 - - - 0.044 - 1.616 0.385 - 80.7 1 2 0 0.0001 15 0 0 0 5.24E+06 4.86E+06 - - - 4.0847 0.9989 221125_WJC_METTL3_EV_vs_WT_F04.21576.21576.2 1.11E-06 Sep-40 R.YAFGQETNVPLNNFSADQVTR.A sp|O43678|NDUA2_HUMAN 1 2370.124 5.77 54525 21576 2 2370.114015 1186.0693 NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 2 OS=Homo sapiens OX=9606 GN=NDUFA2 PE=1 SV=3 4.37 3475.8 - 320836 - - - -4.2289 - 2.546 0.53 - 47.3 1 2 0 -0.01 21 0 0 0 9.79E+06 1.70E+06 - - - 5.25 1 221125_WJC_METTL3_EV_vs_WT_F04.21578.21578.3 2.23E-05 19/72 K.ESSHSGVVLSVEEVEAGLK.G "sp|Q9NRA8|4ET_HUMAN,tr|B1AKL4|B1AKL4_HUMAN,tr|B0QYZ7|B0QYZ7_HUMAN" 3 1954.9848 1.14 54526 21578 3 1954.98257 652.6689 Eukaryotic translation initiation factor 4E transporter OS=Homo sapiens OX=9606 GN=EIF4ENIF1 PE=1 SV=2 4.48 3476 - 3.02E+06 - - - -1.1156 - 3.696 0.587 - 563.4 1 2 0 -0.0022 19 0 0 0 7.03E+07 6.14E+07 - - - 8.2955 1 221125_WJC_METTL3_EV_vs_WT_F04.21581.21581.2 9.35E-11 16/36 R.GGTVPADLEAAAASLPSSK.E "sp|Q9Y6D9|MD1L1_HUMAN,tr|C9JKI7|C9JKI7_HUMAN" 2 1740.8894 3.81 54528 21581 2 1740.886254 871.452 Mitotic spindle assembly checkpoint protein MAD1 OS=Homo sapiens OX=9606 GN=MAD1L1 PE=1 SV=2 4.37 3476.4 - 849989 - - - -1.8037 - 3.208 0.673 - 623.4 1 2 0 -0.0031 19 0 0 0 9.72E+07 2.55E+07 - - - 6.8766 1 221125_WJC_METTL3_EV_vs_WT_F04.21587.21587.3 2.46E-08 20/84 R.QGNGPVLVC[160.03]APSNIAVDQLTEK.L sp|Q92900|RENT1_HUMAN 1 2309.1685 2.03 54532 21587 3 2309.16474 770.7301 Regulator of nonsense transcripts 1 OS=Homo sapiens OX=9606 GN=UPF1 PE=1 SV=2 4.37 3477 - 1.35E+06 - - - -1.6482 - 3.884 0.486 - 359.2 1 2 0 -0.0038 22 0 0 0 2.54E+07 1.25E+07 - - - 7.1743 0.9997 221125_WJC_METTL3_EV_vs_WT_F04.21594.21594.4 2.14E-05 18/102 R.EGISFHFTPVLVC[160.03]KDPIR.T sp|Q9BRR6|ADPGK_HUMAN 1 2114.0983 0.98 54537 21594 4 2114.096835 529.5318 ADP-dependent glucokinase OS=Homo sapiens OX=9606 GN=ADPGK PE=1 SV=1 6.84 3477.9 - 1.49E+06 - - - -0.6845 - 3.473 0.423 - 207.5 1 2 1 -0.0014 18 0 0 0 4.02E+07 4.10E+07 - - - 3.3339 1 221125_WJC_METTL3_EV_vs_WT_F04.21595.21595.3 6.44E-10 15/60 K.HTYLPLEVC[160.03]NIVAGQR.C "sp|Q9UKV8|AGO2_HUMAN,sp|Q9UL18|AGO1_HUMAN,sp|Q9H9G7|AGO3_HUMAN,sp|Q9HCK5|AGO4_HUMAN,tr|A0A6I8PTZ8|A0A6I8PTZ8_HUMAN,tr|Q5TA58|Q5TA58_HUMAN" 6 1868.9567 1.21 54538 21595 3 1868.954333 623.9928 Protein argonaute-2 OS=Homo sapiens OX=9606 GN=AGO2 PE=1 SV=3 6.74 3478 - 1.20E+06 - - - -1.2681 - 3.321 0.44 - 293.9 1 2 0 -0.0024 16 0 0 0 1.54E+07 1.27E+07 - - - 6.5246 0.9998 221125_WJC_METTL3_EV_vs_WT_F04.21596.21596.3 0.000424 Dec-44 R.K[136.11]IEFSLPDLEGR[166.11].T "sp|P35998|PRS7_HUMAN,tr|C9JX88|C9JX88_HUMAN" 2 1420.7681 0.71 54539 21596 3 1420.766751 474.5966 26S proteasome regulatory subunit 7 OS=Homo sapiens OX=9606 GN=PSMC2 PE=1 SV=3 4.68 3478.1 - 826706 - - - -0.9495 - 2.215 0.361 - 314.2 1 2 0 -0.0014 12 0 0 0 1.68E+07 2.35E+07 - - - 4.7687 0.9963 221125_WJC_METTL3_EV_vs_WT_F04.21599.21599.2 0.00043 16-Aug K.LLQDFFNGK[136.11].E "sp|P54652|HSP72_HUMAN,sp|P11142|HSP7C_HUMAN,sp|P17066|HSP76_HUMAN,tr|E9PNE6|E9PNE6_HUMAN,tr|A8K7Q2|A8K7Q2_HUMAN,tr|E9PKE3|E9PKE3_HUMAN,tr|E9PN89|E9PN89_HUMAN" 7 1088.5746 0.86 54540 21599 2 1088.569997 545.2946 Heat shock-related 70 kDa protein 2 OS=Homo sapiens OX=9606 GN=HSPA2 PE=1 SV=1 5.84 3478.5 - 2.07E+06 - - - -4.2239 - 1.598 0.412 - 155.6 1 2 0 -0.0046 9 0 0 0 6.62E+07 7.66E+07 - - - 3.4387 1 221125_WJC_METTL3_EV_vs_WT_F04.21612.21612.3 3.43E-10 23/72 K.FEPIHGNFLLTGAYDNTAK.L sp|O43172|PRP4_HUMAN 1 2107.0375 12.35 54548 21612 3 2107.034064 703.3531 U4\U6 small nuclear ribonucleoprotein Prp4 OS=Homo sapiens OX=9606 GN=PRPF4 PE=1 SV=2 5.32 3479.9 - 3.38E+06 - - - -1.6094 - 3.471 0.489 - 785.1 1 2 0 -0.0034 19 0 0 0 8.87E+07 7.18E+06 - - - 7.0483 1 221125_WJC_METTL3_EV_vs_WT_F04.21613.21613.3 1.61E-16 28/72 K.SVRPNDEVTAVLAVQTELK.E sp|P12273|PIP_HUMAN 1 2068.1164 260.53 54549 21613 3 2068.116045 690.3794 Prolactin-inducible protein OS=Homo sapiens OX=9606 GN=PIP PE=1 SV=1 4.68 3480 - 2.14E+06 - - - -0.1881 - 5.117 0.667 - 1336 1 2 0 -0.0004 19 0 0 0 4.19E+08 1.61E+06 - - - 9.9872 0.7966 221125_WJC_METTL3_EV_vs_WT_F04.21626.21626.3 5.87E-06 Dec-68 K.MNLSEEVDLEDYVARPDK.L sp|P43686|PRS6B_HUMAN 1 2121.9889 0.78 54557 21626 3 2121.975673 708.3369 26S proteasome regulatory subunit 6B OS=Homo sapiens OX=9606 GN=PSMC4 PE=1 SV=2 4.02 3481.5 - 3.38E+06 - - - -6.2097 - 2.14 0.145 - 117.3 1 2 0 -0.0132 18 0 0 0 1.22E+08 1.57E+08 - - - 2.0474 1 221125_WJC_METTL3_EV_vs_WT_F04.21631.21631.4 1.15E-07 15/114 K.GNPQGFNQGLDC[160.03]DVIVAEVR[166.11].S sp|Q86U44|MTA70_HUMAN 1 2197.0461 0 54558 21631 4 2197.042911 550.2688 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 4.03 3482.2 - 4.40E+06 - - - -1.4679 - 2.538 0.615 - 145.4 1 2 0 -0.0032 20 0 0 0 6.98E+05 3.52E+08 - - - 4.8894 1 221125_WJC_METTL3_EV_vs_WT_F04.21635.21635.2 7.02E-09 21/42 R.GDWSVGAPGGVQEITYTVPADK.C sp|Q96I24|FUBP3_HUMAN 1 2246.0855 2.77 54560 21635 2 2246.082107 1124.05 Far upstream element-binding protein 3 OS=Homo sapiens OX=9606 GN=FUBP3 PE=1 SV=2 4.03 3482.7 - 9.24E+06 - - - -1.5231 - 3.261 0.635 - 702.2 1 2 0 -0.0034 22 0 0 0 1.01E+09 3.65E+08 - - - 6.6361 0.9997 221125_WJC_METTL3_EV_vs_WT_F04.21641.21641.3 0.00372 15/84 R.GDWSVGAPGGVQEITYTVPADK.C sp|Q96I24|FUBP3_HUMAN 1 2246.0855 2.26 54561 21641 3 2246.076592 749.7025 Far upstream element-binding protein 3 OS=Homo sapiens OX=9606 GN=FUBP3 PE=1 SV=2 4.03 3483.6 - 3.78E+07 - - - -3.9785 - 2.242 0.502 - 153.1 1 2 0 -0.0089 22 0 0 0 1.05E+09 4.63E+08 - - - 6.0485 1 221125_WJC_METTL3_EV_vs_WT_F04.21648.21648.2 9.70E-08 16/42 R.GDWSVGAPGGVQEITYTVPADK[136.11].C sp|Q96I24|FUBP3_HUMAN 1 2254.0997 2.77 54563 21648 2 2254.084688 1128.0571 Far upstream element-binding protein 3 OS=Homo sapiens OX=9606 GN=FUBP3 PE=1 SV=2 4.03 3484.5 - 9.63E+06 - - - -6.6723 - 2.629 0.611 - 324 1 2 0 -0.015 22 0 0 0 1.01E+09 3.65E+08 - - - 5.9256 1 221125_WJC_METTL3_EV_vs_WT_F04.21651.21651.2 3.25E-06 18/26 F.NQGLDC[160.03]DVIVAEVR[166.11].S sp|Q86U44|MTA70_HUMAN 1 1596.7805 0.01 54564 21651 2 1596.765348 799.3975 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 4.03 3484.9 - 3.64E+06 - - - -9.5054 - 3.452 0.637 - 1188.8 1 1 0 -0.0152 14 0 0 0 2.46E+06 3.01E+08 - - - 6.8502 1 221125_WJC_METTL3_EV_vs_WT_F04.21669.21669.4 1.33E-06 26/114 R.TLYVHWTDAGQLTPALLHSR.C "sp|Q8IY67|RAVR1_HUMAN,tr|E9PAU2|E9PAU2_HUMAN,tr|A0A087WZ13|A0A087WZ13_HUMAN" 3 2278.1859 0.63 54567 21669 4 2278.181964 570.5537 Ribonucleoprotein PTB-binding 1 OS=Homo sapiens OX=9606 GN=RAVER1 PE=1 SV=1 6.61 3487.6 - 6.58E+06 - - - -1.7062 - 3.967 0.544 - 329.8 1 2 0 -0.0039 20 0 0 0 2.74E+08 4.34E+08 - - - 4.4206 0.9999 221125_WJC_METTL3_EV_vs_WT_F04.21678.21678.3 7.13E-07 19/60 R.EGEITHLQLEIGNLEK.T "sp|P82094|TMF1_HUMAN,tr|A0A2R8Y7M0|A0A2R8Y7M0_HUMAN" 2 1821.9472 2.9 54568 21678 3 1821.943239 608.323 TATA element modulatory factor OS=Homo sapiens OX=9606 GN=TMF1 PE=1 SV=2 4.48 3489.1 - 3.51E+06 - - - -2.1976 - 3.095 0.392 - 351.3 1 2 0 -0.004 16 0 0 0 1.14E+08 3.94E+07 - - - 5.8082 0.995 221125_WJC_METTL3_EV_vs_WT_F04.21688.21688.4 8.10E-08 22/114 R.TLYVHWTDAGQLTPALLHSR[166.11].C "sp|Q8IY67|RAVR1_HUMAN,tr|E9PAU2|E9PAU2_HUMAN,tr|A0A087WZ13|A0A087WZ13_HUMAN" 3 2288.1941 0.63 54570 21688 4 2289.189717 573.0558 Ribonucleoprotein PTB-binding 1 OS=Homo sapiens OX=9606 GN=RAVER1 PE=1 SV=1 6.61 3490.5 - 1.53E+07 - - - 435.1012 - 2.888 0.52 - 265.8 1 2 0 0.9956 20 0 0 0 2.73E+08 4.33E+08 - - - 3.8309 1 221125_WJC_METTL3_EV_vs_WT_F04.21689.21689.2 1.31E-11 18/34 K.TVDFTQDSNYLLTGGQDK[136.11].L sp|Q9Y3F4|STRAP_HUMAN 1 2008.9469 0.69 54571 21689 2 2008.939583 1005.4807 Serine-threonine kinase receptor-associated protein OS=Homo sapiens OX=9606 GN=STRAP PE=1 SV=1 3.93 3490.6 - 4.32E+06 - - - -3.6497 - 3.366 0.696 - 1038.4 1 2 0 -0.0073 18 0 0 0 7.87E+07 1.14E+08 - - - 7.1634 1 221125_WJC_METTL3_EV_vs_WT_F04.21692.21692.3 2.49E-05 29/76 R.TLYVHWTDAGQLTPALLHSR.C "sp|Q8IY67|RAVR1_HUMAN,tr|E9PAU2|E9PAU2_HUMAN,tr|A0A087WZ13|A0A087WZ13_HUMAN" 3 2278.1859 0.5 54572 21692 3 2278.174688 760.4026 Ribonucleoprotein PTB-binding 1 OS=Homo sapiens OX=9606 GN=RAVER1 PE=1 SV=1 6.61 3491 - 4.73E+06 - - - -4.9 - 4.468 0.617 - 817.9 1 2 0 -0.0112 20 0 0 0 7.14E+07 1.42E+08 - - - 9.0475 0.9994 221125_WJC_METTL3_EV_vs_WT_F04.21693.21693.4 2.79E-05 20/96 K.AAIDWFDGKEFHGNIIK.V "sp|Q92804|RBP56_HUMAN,tr|A0A075B7D9|A0A075B7D9_HUMAN" 2 1959.9843 1.05 54573 21693 4 1959.978563 491.0034 TATA-binding protein-associated factor 2N OS=Homo sapiens OX=9606 GN=TAF15 PE=1 SV=1 5.38 3491.1 - 2.44E+06 - - - -2.9255 - 3.287 0.452 - 362 1 2 1 -0.0057 17 0 0 0 4.81E+07 4.56E+07 - - - 3.5718 0.9999 221125_WJC_METTL3_EV_vs_WT_F04.21695.21695.3 9.29E-05 17/76 K.FTASAGIQVVGDDLTVTNPK.R "sp|P06733|ENOA_HUMAN,tr|A0A2R8Y6G6|A0A2R8Y6G6_HUMAN" 2 2032.0477 1.9 54575 21695 3 2032.041913 678.3565 Alpha-enolase OS=Homo sapiens OX=9606 GN=ENO1 PE=1 SV=2 4.21 3491.3 - 3.38E+06 - - - -2.841 - 2.711 0.474 - 312.1 1 2 0 -0.0058 20 0 0 0 5.96E+07 3.14E+07 - - - 6.2425 0.9995 221125_WJC_METTL3_EV_vs_WT_F04.21696.21696.3 8.39E-07 17/76 K.FTASAGIQVVGDDLTVTNPK[136.11].R "sp|P06733|ENOA_HUMAN,tr|A0A2R8Y6G6|A0A2R8Y6G6_HUMAN" 2 2040.0619 1.9 54576 21696 3 2040.051906 681.0279 Alpha-enolase OS=Homo sapiens OX=9606 GN=ENO1 PE=1 SV=2 4.21 3491.4 - 2.28E+06 - - - -4.892 - 2.977 0.476 - 326.8 1 2 0 -0.01 20 0 0 0 5.96E+07 3.14E+07 - - - 6.4908 1 221125_WJC_METTL3_EV_vs_WT_F04.21700.21700.2 1.13E-06 17/34 K.TVDFTQDSNYLLTGGQDK.L sp|Q9Y3F4|STRAP_HUMAN 1 2000.9327 0.69 54578 21700 2 2000.926223 1001.4736 Serine-threonine kinase receptor-associated protein OS=Homo sapiens OX=9606 GN=STRAP PE=1 SV=1 3.93 3491.9 - 3.32E+06 - - - -3.2445 - 3.253 0.63 - 681 1 2 0 -0.0065 18 0 0 0 7.87E+07 1.14E+08 - - - 6.5922 1 221125_WJC_METTL3_EV_vs_WT_F04.21701.21701.2 4.21E-11 19/36 K.TSSAETPTIPLGSAVEAIK[136.11].A "sp|Q16891|MIC60_HUMAN,tr|B9A067|B9A067_HUMAN,tr|C9J406|C9J406_HUMAN,tr|H7C463|H7C463_HUMAN" 4 1879.003 1.57 54579 21701 2 1878.998674 940.5088 MICOS complex subunit MIC60 OS=Homo sapiens OX=9606 GN=IMMT PE=1 SV=1 4.53 3492.1 - 1.57E+06 - - - -2.2884 - 3.242 0.645 - 667.4 1 2 0 -0.0043 19 0 0 0 5.72E+08 3.64E+08 - - - 6.6953 0.9999 221125_WJC_METTL3_EV_vs_WT_F04.21705.21705.3 9.21E-10 17/68 K.TVDFTQDSNYLLTGGQDK[136.11].L sp|Q9Y3F4|STRAP_HUMAN 1 2008.9469 0.43 54581 21705 3 2008.939691 670.6562 Serine-threonine kinase receptor-associated protein OS=Homo sapiens OX=9606 GN=STRAP PE=1 SV=1 3.93 3492.5 - 2.88E+06 - - - -3.5959 - 2.81 0.634 - 336.8 1 2 0 -0.0072 18 0 0 0 3.46E+07 8.03E+07 - - - 8.1792 1 221125_WJC_METTL3_EV_vs_WT_F04.21707.21707.2 7.60E-10 20/36 K.TSSAETPTIPLGSAVEAIK.A "sp|Q16891|MIC60_HUMAN,tr|B9A067|B9A067_HUMAN,tr|C9J406|C9J406_HUMAN,tr|H7C463|H7C463_HUMAN" 4 1870.9888 1.57 54583 21707 2 1870.986488 936.5017 MICOS complex subunit MIC60 OS=Homo sapiens OX=9606 GN=IMMT PE=1 SV=1 4.53 3492.8 - 2.39E+06 - - - -1.2218 - 3.589 0.65 - 740 1 2 0 -0.0023 19 0 0 0 5.72E+08 3.64E+08 - - - 6.9829 1 221125_WJC_METTL3_EV_vs_WT_F04.21713.21713.3 1.45E-10 20/64 R.TSIFWNDVK[136.11]DPVSIEER[166.11].A "sp|P55884|EIF3B_HUMAN,tr|C9JQN7|C9JQN7_HUMAN,tr|C9JZG1|C9JZG1_HUMAN" 3 2052.0283 0.75 54586 21713 3 2052.026926 685.0167 Eukaryotic translation initiation factor 3 subunit B OS=Homo sapiens OX=9606 GN=EIF3B PE=1 SV=3 4.32 3493.5 - 2.68E+06 - - - -0.6652 - 3.836 0.573 - 503.1 1 2 1 -0.0014 17 0 0 0 4.09E+07 5.46E+07 - - - 8.3244 0.9927 221125_WJC_METTL3_EV_vs_WT_F04.21714.21714.3 5.70E-07 17/64 T.YSDNQPGVLIQVYEGER[166.11].A "sp|P0DMV8|HS71A_HUMAN,sp|P34931|HS71L_HUMAN,sp|P11142|HSP7C_HUMAN,sp|P0DMV9|HS71B_HUMAN,tr|E9PNE6|E9PNE6_HUMAN,tr|A8K7Q2|A8K7Q2_HUMAN,tr|E9PKE3|E9PKE3_HUMAN,tr|E9PS65|E9PS65_HUMAN,tr|Q53FA3|Q53FA3_HUMAN,tr|V9GZ37|V9GZ37_HUMAN,tr|A0A0G2JIW1|A0A0G2JIW1_HUMAN" 11 1975.9515 0.12 54587 21714 3 1975.944806 659.6578 Heat shock 70 kDa protein 1A OS=Homo sapiens OX=9606 GN=HSPA1A PE=1 SV=1 4.14 3493.6 - 1.27E+06 - - - -3.3827 - 2.861 0.576 - 433.7 1 1 0 -0.0067 17 0 0 0 3.07E+06 2.55E+07 - - - 7.6156 0.9999 221125_WJC_METTL3_EV_vs_WT_F04.21720.21720.4 1.80E-09 20/132 K.IVGAPMHDLLLWNNATVTTC[160.03]HSK.T "sp|P11586|C1TC_HUMAN,tr|F5H2F4|F5H2F4_HUMAN,tr|V9GZ78|V9GZ78_HUMAN,tr|V9GYY3|V9GYY3_HUMAN" 4 2577.2832 2.93 54591 21720 4 2577.274902 645.3281 "C-1-tetrahydrofolate synthase, cytoplasmic OS=Homo sapiens OX=9606 GN=MTHFD1 PE=1 SV=4" 6.91 3494.3 - 2.17E+06 - - - -3.2193 - 3.397 0.525 - 205.2 1 2 0 -0.0083 23 0 0 0 2.98E+07 1.02E+07 - - - 4.1895 1 221125_WJC_METTL3_EV_vs_WT_F04.21721.21721.3 5.57E-08 25/76 R.TLYVHWTDAGQLTPALLHSR[166.11].C "sp|Q8IY67|RAVR1_HUMAN,tr|E9PAU2|E9PAU2_HUMAN,tr|A0A087WZ13|A0A087WZ13_HUMAN" 3 2288.1941 0.5 54592 21721 3 2288.191486 763.7387 Ribonucleoprotein PTB-binding 1 OS=Homo sapiens OX=9606 GN=RAVER1 PE=1 SV=1 6.61 3494.5 - 2.02E+06 - - - -1.1516 - 4.309 0.629 - 568.9 1 2 0 -0.0026 20 0 0 0 7.14E+07 1.42E+08 - - - 9.0957 0.9999 221125_WJC_METTL3_EV_vs_WT_F04.21722.21722.3 5.64E-09 18/68 K.TVDFTQDSNYLLTGGQDK.L sp|Q9Y3F4|STRAP_HUMAN 1 2000.9327 0.45 54593 21722 3 2000.92517 667.9848 Serine-threonine kinase receptor-associated protein OS=Homo sapiens OX=9606 GN=STRAP PE=1 SV=1 3.93 3494.6 - 1.86E+06 - - - -3.7707 - 2.95 0.592 - 345.5 1 2 0 -0.0075 18 0 0 0 3.46E+07 7.64E+07 - - - 7.8319 1 221125_WJC_METTL3_EV_vs_WT_F04.21728.21728.3 3.45E-06 15/72 K.FHMVDGNVSGEFTDLVPEK.H "sp|O95433|AHSA1_HUMAN,tr|H0YJ63|H0YJ63_HUMAN,tr|G3V438|G3V438_HUMAN" 3 2119.9885 1.74 54596 21728 3 2119.98604 707.6701 Activator of 90 kDa heat shock protein ATPase homolog 1 OS=Homo sapiens OX=9606 GN=AHSA1 PE=1 SV=1 4.31 3495.4 - 3.61E+06 - - - -1.1396 - 2.724 0.545 - 179 1 2 0 -0.0024 19 0 0 0 8.73E+07 5.01E+07 - - - 7.0775 0.9999 221125_WJC_METTL3_EV_vs_WT_F04.21730.21730.3 0.0484 15/72 K.TSSAETPTIPLGSAVEAIK[136.11].A "sp|Q16891|MIC60_HUMAN,tr|B9A067|B9A067_HUMAN,tr|C9J406|C9J406_HUMAN,tr|H7C463|H7C463_HUMAN" 4 1879.003 1.68 54598 21730 3 1879.002153 627.3416 MICOS complex subunit MIC60 OS=Homo sapiens OX=9606 GN=IMMT PE=1 SV=1 4.53 3495.5 - 2.22E+06 - - - -0.4369 - 2.82 0.372 - 223.3 1 2 0 -0.0008 19 0 0 0 2.04E+08 1.21E+08 - - - 5.2343 0.9985 221125_WJC_METTL3_EV_vs_WT_F04.21733.21733.3 2.34E-05 13/56 R.LR[166.11]GWEAFLNAPEANR[166.11].G sp|O43719|HTSF1_HUMAN 1 1762.9018 1.75 54601 21733 3 1762.895631 588.6412 HIV Tat-specific factor 1 OS=Homo sapiens OX=9606 GN=HTATSF1 PE=1 SV=1 6.14 3495.9 - 554013 - - - -3.4948 - 2.567 0.423 - 155.6 1 2 1 -0.0062 15 0 0 0 6.02E+06 3.44E+06 - - - 5.7143 0.8376 221125_WJC_METTL3_EV_vs_WT_F04.21738.21738.4 1.73 Jul-96 R.TIFSEC[160.03]FYTMAMNELWR[166.11].A "sp|P51606|RENBP_HUMAN,tr|H7C1A7|H7C1A7_HUMAN,tr|A6NKZ2|A6NKZ2_HUMAN" 3 2207.9718 0.47 54604 21738 4 2207.969547 553.0002 N-acylglucosamine 2-epimerase OS=Homo sapiens OX=9606 GN=RENBP PE=1 SV=2 4.53 3496.5 - 1.03E+06 - - - -1.0086 - 1.221 0.106 - 25 1 2 0 -0.0022 17 0 0 0 1.11E+07 2.38E+07 - - - 0.2173 0.962 221125_WJC_METTL3_EV_vs_WT_F04.21739.21739.2 0.00737 Aug-34 K.QTQTFTTYSDNQPGVLIQ.V "sp|P11142|HSP7C_HUMAN,tr|E9PNE6|E9PNE6_HUMAN,tr|A8K7Q2|A8K7Q2_HUMAN,tr|E9PKE3|E9PKE3_HUMAN,tr|E9PS65|E9PS65_HUMAN" 5 2039.98 - 54605 21739 2 2039.97966 1020.9973 Heat shock cognate 71 kDa protein OS=Homo sapiens OX=9606 GN=HSPA8 PE=1 SV=1 3.8 3496.7 - 575912 - - - -0.1667 - 1.375 0.396 - 93.8 1 1 0 -0.0003 18 0 0 0 - - - - - 2.7487 1 221125_WJC_METTL3_EV_vs_WT_F04.21745.21745.3 3.93E-12 21/72 K.FHMVDGNVSGEFTDLVPEK[136.11].H "sp|O95433|AHSA1_HUMAN,tr|H0YJ63|H0YJ63_HUMAN,tr|G3V438|G3V438_HUMAN" 3 2128.0027 1.66 54609 21745 3 2127.996308 710.3415 Activator of 90 kDa heat shock protein ATPase homolog 1 OS=Homo sapiens OX=9606 GN=AHSA1 PE=1 SV=1 4.31 3497.3 - 2.11E+06 - - - -2.9831 - 3.895 0.599 - 417.9 1 2 0 -0.0063 19 0 0 0 9.91E+07 5.97E+07 - - - 8.557 0.9995 221125_WJC_METTL3_EV_vs_WT_F04.21748.21748.3 0.00196 14/64 R.DAPTHLPSVDLSNPFTK.E sp|Q5VT52|RPRD2_HUMAN 1 1837.921 1.8 54612 21748 3 1837.921029 613.6476 Regulation of nuclear pre-mRNA domain-containing protein 2 OS=Homo sapiens OX=9606 GN=RPRD2 PE=1 SV=1 5.21 3497.6 - 1.01E+06 - - - 0.0005 - 1.943 0.32 - 65.2 1 2 0 0 17 0 0 0 1.47E+07 8.17E+06 - - - 3.7857 1 221125_WJC_METTL3_EV_vs_WT_F04.21749.21749.2 9.18E-08 14/30 R.IINEPTAAAIAYGLDK[136.11].R "sp|P11021|BIP_HUMAN,sp|P54652|HSP72_HUMAN,sp|P34931|HS71L_HUMAN,sp|P11142|HSP7C_HUMAN,tr|E9PKE3|E9PKE3_HUMAN,tr|E9PN89|E9PN89_HUMAN,tr|A0A7P0TB36|A0A7P0TB36_HUMAN,tr|E9PLF4|E9PLF4_HUMAN,tr|A0A7P0TAI0|A0A7P0TAI0_HUMAN,tr|Q53FA3|Q53FA3_HUMAN,tr|E9PI65|E9PI65_HUMAN" 11 1666.9021 0.18 54613 21749 2 1666.901899 834.4583 Endoplasmic reticulum chaperone BiP OS=Homo sapiens OX=9606 GN=HSPA5 PE=1 SV=2 4.37 3497.8 - 686399 - - - -0.1428 - 3.142 0.606 - 536.6 1 2 0 -0.0002 16 0 0 0 1.50E+06 8.30E+06 - - - 6.3315 1 221125_WJC_METTL3_EV_vs_WT_F04.21754.21754.4 2.14E-11 21/132 R.AITVFSPDGHLFQVEYAQEAVK[136.11]K[136.11].G "sp|Q8TAA3|PSMA8_HUMAN,sp|O14818|PSA7_HUMAN,tr|F5GY34|F5GY34_HUMAN" 3 2592.3559 0.73 54616 21754 4 2592.354976 649.0962 Proteasome subunit alpha-type 8 OS=Homo sapiens OX=9606 GN=PSMA8 PE=2 SV=3 5.45 3498.4 - 1.47E+06 - - - -0.3522 - 4.302 0.634 - 348.9 1 2 0 -0.0009 23 0 0 0 2.30E+07 3.17E+07 - - - 5.2168 1 221125_WJC_METTL3_EV_vs_WT_F04.21757.21757.4 1.88E-07 25/126 R.IDWPVGSPATIHYPALDGHLSR.Y "sp|O15498|YKT6_HUMAN,tr|A0A7I2V4L6|A0A7I2V4L6_HUMAN,tr|A0A7I2V3V7|A0A7I2V3V7_HUMAN,tr|A0A7I2V3A1|A0A7I2V3A1_HUMAN" 4 2401.2179 6.56 54619 21757 4 2401.219377 601.3117 Synaptobrevin homolog YKT6 OS=Homo sapiens OX=9606 GN=YKT6 PE=1 SV=1 5.98 3498.7 - 1.17E+06 - - - 0.6239 - 2.857 0.502 - 235.9 1 2 0 0.0015 22 0 0 0 4.63E+07 7.06E+06 - - - 3.9385 1 221125_WJC_METTL3_EV_vs_WT_F04.21759.21759.3 1.67E-12 23/92 K.ENALVQMADANQAQLAMNHLSGQR[166.11].L sp|O95758|PTBP3_HUMAN 1 2619.2521 1.52 54621 21759 3 2619.249714 874.0913 Polypyrimidine tract-binding protein 3 OS=Homo sapiens OX=9606 GN=PTBP3 PE=1 SV=2 5.32 3499 - 763600 - - - -0.9197 - 4.384 0.685 - 569.3 1 2 0 -0.0024 24 0 0 0 1.15E+07 7.58E+06 - - - 9.6091 0.9999 221125_WJC_METTL3_EV_vs_WT_F04.21770.21770.3 1.94E-05 14/72 K.TSSAETPTIPLGSAVEAIK.A "sp|Q16891|MIC60_HUMAN,tr|B9A067|B9A067_HUMAN,tr|C9J406|C9J406_HUMAN,tr|H7C463|H7C463_HUMAN" 4 1870.9888 1.68 54630 21770 3 1870.989282 624.6702 MICOS complex subunit MIC60 OS=Homo sapiens OX=9606 GN=IMMT PE=1 SV=1 4.53 3500.2 - 7.39E+06 - - - 0.2715 - 2.58 0.401 - 218.9 1 2 0 0.0005 19 0 0 0 2.04E+08 1.21E+08 - - - 5.3391 1 221125_WJC_METTL3_EV_vs_WT_F04.21772.21772.3 1.14E-10 17/72 R.VQTLEELEELGKEEC[160.03]FQNK.E sp|Q9BVJ6|UT14A_HUMAN 1 2322.1049 3 54632 21772 3 2322.104974 775.0423 U3 small nucleolar RNA-associated protein 14 homolog A OS=Homo sapiens OX=9606 GN=UTP14A PE=1 SV=1 4.21 3500.4 - 1.46E+06 - - - 0.0133 - 3.91 0.578 - 312.5 1 2 1 0 19 0 0 0 3.47E+07 1.16E+07 - - - 8.3341 1 221125_WJC_METTL3_EV_vs_WT_F04.21774.21774.3 8.49E-10 19/92 R.LLSTC[160.03]GLVQSVELQEKPDLAESPK.E sp|Q9Y3A4|RRP7A_HUMAN 1 2640.368 1.1 54634 21774 3 2640.365383 881.13 Ribosomal RNA-processing protein 7 homolog A OS=Homo sapiens OX=9606 GN=RRP7A PE=1 SV=2 4.41 3500.6 - 999884 - - - -1.004 - 4.077 0.513 - 258.5 1 2 0 -0.0027 24 0 0 0 1.20E+07 1.09E+07 - - - 7.5228 0.9997 221125_WJC_METTL3_EV_vs_WT_F04.21776.21776.3 4.04E-06 14/68 K.DLEGENIEIVFAK[136.11]PPDQK[136.11].R "sp|O60506|HNRPQ_HUMAN,tr|A0A7I2YQV8|A0A7I2YQV8_HUMAN,tr|A0A7I2YQN2|A0A7I2YQN2_HUMAN,tr|A0A7I2V4Z0|A0A7I2V4Z0_HUMAN,tr|B7Z645|B7Z645_HUMAN,tr|A0A7I2V2F2|A0A7I2V2F2_HUMAN,tr|A0A7I2V346|A0A7I2V346_HUMAN,tr|A0A7I2V309|A0A7I2V309_HUMAN" 8 2057.0652 2.54 54636 21776 3 2057.075492 686.6957 Heterogeneous nuclear ribonucleoprotein Q OS=Homo sapiens OX=9606 GN=SYNCRIP PE=1 SV=2 4.18 3500.8 - 904499 - - - 5.0096 - 2.446 0.573 - 130.9 1 2 0 0.0103 18 0 0 0 1.79E+08 7.03E+07 - - - 7.1528 1 221125_WJC_METTL3_EV_vs_WT_F04.21778.21778.3 8.41E-13 26/92 K.ENALVQMADANQAQLAMNHLSGQR.L sp|O95758|PTBP3_HUMAN 1 2609.2439 1.52 54638 21778 3 2609.238516 870.7552 Polypyrimidine tract-binding protein 3 OS=Homo sapiens OX=9606 GN=PTBP3 PE=1 SV=2 5.32 3501.1 - 761052 - - - -2.0454 - 4.849 0.644 - 750.3 1 2 0 -0.0053 24 0 0 0 1.15E+07 7.58E+06 - - - 9.3853 1 221125_WJC_METTL3_EV_vs_WT_F04.21783.21783.3 4.52E-10 21/76 R.VPEEEKDTNVQVLMVLGAGR.G "sp|O14744|ANM5_HUMAN,tr|H0YJ77|H0YJ77_HUMAN,tr|H0YJX6|H0YJX6_HUMAN" 3 2183.1256 2.19 54641 21783 3 2183.121255 728.7158 Protein arginine N-methyltransferase 5 OS=Homo sapiens OX=9606 GN=PRMT5 PE=1 SV=4 4.41 3501.7 - 3.26E+06 - - - -1.9985 - 3.467 0.628 - 598.5 1 2 1 -0.0044 20 0 0 0 7.71E+07 3.52E+07 - - - 8.5566 1 221125_WJC_METTL3_EV_vs_WT_F04.21787.21787.3 1.17E-09 19/92 R.LLSTC[160.03]GLVQSVELQEK[136.11]PDLAESPK[136.11].E sp|Q9Y3A4|RRP7A_HUMAN 1 2656.3964 1.1 54645 21787 3 2656.395382 886.4728 Ribosomal RNA-processing protein 7 homolog A OS=Homo sapiens OX=9606 GN=RRP7A PE=1 SV=2 4.41 3502.1 - 1.25E+06 - - - -0.396 - 4.171 0.615 - 299.8 1 2 0 -0.0011 24 0 0 0 1.20E+07 1.09E+07 - - - 8.7134 1 221125_WJC_METTL3_EV_vs_WT_F04.21788.21788.3 1.39E-05 15/64 R.DAPTHLPSVDLSNPFTK[136.11].E sp|Q5VT52|RPRD2_HUMAN 1 1845.9352 1.8 54646 21788 3 1845.937231 616.319 Regulation of nuclear pre-mRNA domain-containing protein 2 OS=Homo sapiens OX=9606 GN=RPRD2 PE=1 SV=1 5.21 3502.2 - 724745 - - - 1.0851 - 2.683 0.473 - 305 1 2 0 0.002 17 0 0 0 1.47E+07 8.17E+06 - - - 6.3062 1 221125_WJC_METTL3_EV_vs_WT_F04.21789.21789.4 2.96E-11 23/102 K.LAFPSPFGHLSEGFSHSR.W "sp|Q13501|SQSTM_HUMAN,tr|E9PFW8|E9PFW8_HUMAN,tr|E7EMC7|E7EMC7_HUMAN,tr|C9JRJ8|C9JRJ8_HUMAN" 4 1971.9591 1.35 54647 21789 4 1971.957053 493.9971 Sequestosome-1 OS=Homo sapiens OX=9606 GN=SQSTM1 PE=1 SV=1 6.92 3502.3 - 492240 - - - -1.0609 - 3.98 0.609 - 432.5 1 2 0 -0.0021 18 0 0 0 6.76E+06 5.01E+06 - - - 4.9993 1 221125_WJC_METTL3_EV_vs_WT_F04.21794.21794.2 6.53E-11 18/38 K.GNPQGFNQGLDC[160.03]DVIVAEVR[166.11].S sp|Q86U44|MTA70_HUMAN 1 2197.0461 0.01 54650 21794 2 2197.044633 1099.5303 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 4.03 3502.8 - 3.42E+06 - - - -0.6841 - 3.46 0.679 - 876.9 1 2 0 -0.0015 20 0 0 0 1.16E+06 1.05E+08 - - - 7.1073 1 221125_WJC_METTL3_EV_vs_WT_F04.21796.21796.4 7.32E-05 16/96 R.WVTYFNKPDIDAWELRK.G "sp|P20674|COX5A_HUMAN,tr|H3BNX8|H3BNX8_HUMAN,tr|H3BRI0|H3BRI0_HUMAN" 3 2180.1055 1.9 54652 21796 4 2180.106385 546.0336 "Cytochrome c oxidase subunit 5A, mitochondrial OS=Homo sapiens OX=9606 GN=COX5A PE=1 SV=2" 6.12 3503 - 1.90E+06 - - - 0.4174 - 2.805 0.518 - 183.7 1 2 0 0.0009 17 0 0 0 3.70E+07 1.95E+07 - - - 4.0925 1 221125_WJC_METTL3_EV_vs_WT_F04.21797.21797.3 3.86E-12 18/80 K.IEEAMDGSETPQLFTVLPEK[136.11]R[166.11].T "sp|Q13435|SF3B2_HUMAN,tr|E9PPJ0|E9PPJ0_HUMAN" 2 2407.206 1.02 54653 21797 3 2407.202934 803.4093 Splicing factor 3B subunit 2 OS=Homo sapiens OX=9606 GN=SF3B2 PE=1 SV=2 4.25 3503.1 - 1.40E+06 - - - -1.2724 - 3.653 0.698 - 378.3 1 2 0 -0.0031 21 0 0 0 3.35E+07 3.27E+07 - - - 9.4272 1 221125_WJC_METTL3_EV_vs_WT_F04.21798.21798.3 9.77E-12 20/80 K.IEEAMDGSETPQLFTVLPEKR.T "sp|Q13435|SF3B2_HUMAN,tr|E9PPJ0|E9PPJ0_HUMAN" 2 2389.1835 0.53 54654 21798 3 2389.185899 797.4018 Splicing factor 3B subunit 2 OS=Homo sapiens OX=9606 GN=SF3B2 PE=1 SV=2 4.25 3503.2 - 1.38E+06 - - - 0.9928 - 3.559 0.694 - 472.6 1 2 0 0.0024 21 0 0 0 3.59E+07 6.73E+07 - - - 9.3203 0.9998 221125_WJC_METTL3_EV_vs_WT_F04.21801.21801.3 3.95E-05 13/60 K.IGDEYFTFITDC[160.03]K[136.11]DPK[136.11].A "sp|P49368|TCPG_HUMAN,tr|B4DUR8|B4DUR8_HUMAN" 2 1963.9208 0.31 54657 21801 3 1963.917792 655.6476 T-complex protein 1 subunit gamma OS=Homo sapiens OX=9606 GN=CCT3 PE=1 SV=4 4.23 3503.6 - 445174 - - - -1.5474 - 2.24 0.532 - 159.6 1 2 1 -0.003 16 0 0 0 5.69E+07 1.81E+08 - - - 6.5397 1 221125_WJC_METTL3_EV_vs_WT_F04.21802.21802.2 2.93E-08 Nov-36 P.APGPASGGSGEVDELFDVK.N "sp|O14579|COPE_HUMAN,tr|M0QXB4|M0QXB4_HUMAN,tr|M0R061|M0R061_HUMAN" 3 1830.8636 1.53 54658 21802 2 1830.868151 916.4391 Coatomer subunit epsilon OS=Homo sapiens OX=9606 GN=COPE PE=1 SV=3 3.92 3503.7 - 412025 - - - 2.5005 - 2.553 0.61 - 177.9 1 1 0 0.0046 19 0 0 0 5.64E+06 3.70E+06 - - - 5.8493 1 221125_WJC_METTL3_EV_vs_WT_F04.21806.21806.3 2.76E-08 24/88 K.VTSVVFHPSQDLVFSASPDATIR[166.11].L sp|Q9UMS4|PRP19_HUMAN 1 2482.2732 1.68 54660 21806 3 2482.275178 828.4317 Pre-mRNA-processing factor 19 OS=Homo sapiens OX=9606 GN=PRPF19 PE=1 SV=1 5.21 3504.2 - 2.10E+06 - - - 0.8134 - 4.21 0.586 - 680.5 1 2 0 0.002 23 0 0 0 3.50E+07 2.09E+07 - - - 8.445 1 221125_WJC_METTL3_EV_vs_WT_F04.21808.21808.3 5.55E-08 24/96 K.IDSIPHLNNSTPLVDPSVYGYGVQK.R sp|Q96I24|FUBP3_HUMAN 1 2712.3759 1.99 54662 21808 3 2712.378297 905.1326 Far upstream element-binding protein 3 OS=Homo sapiens OX=9606 GN=FUBP3 PE=1 SV=2 5.21 3504.4 - 2.17E+06 - - - 0.8852 - 4.213 0.637 - 450.6 1 2 0 0.0024 25 0 0 0 3.80E+09 1.91E+09 - - - 8.95 1 221125_WJC_METTL3_EV_vs_WT_F04.21811.21811.3 6.66E-07 24/96 K.IDSIPHLNNSTPLVDPSVYGYGVQK[136.11].R sp|Q96I24|FUBP3_HUMAN 1 2720.3901 1.99 54665 21811 3 2720.389844 907.804 Far upstream element-binding protein 3 OS=Homo sapiens OX=9606 GN=FUBP3 PE=1 SV=2 5.21 3504.7 - 1.04E+06 - - - -0.0926 - 3.987 0.569 - 481.7 1 2 0 -0.0003 25 0 0 0 3.80E+09 1.91E+09 - - - 8.0656 1 221125_WJC_METTL3_EV_vs_WT_F04.21815.21815.2 1.18E-06 14/22 K.SLNNQFASFIDK.V sp|P04264|K2C1_HUMAN 1 1382.683 706.72 54668 21815 2 1382.684185 692.3488 "Keratin, type II cytoskeletal 1 OS=Homo sapiens OX=9606 GN=KRT1 PE=1 SV=6" 5.55 3505.2 - 2.14E+07 - - - 0.8353 - 2.685 0.607 - 658.1 1 2 0 0.0012 12 0 0 0 4.88E+08 6.90E+05 - - - 6.1227 0.9969 221125_WJC_METTL3_EV_vs_WT_F04.21818.21818.3 7.81E-07 14/64 L.GNQLDGIHLLDPDVVAR[166.11].F sp|Q86U44|MTA70_HUMAN 1 1840.9671 0.02 54670 21818 3 1840.965662 614.663 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 4.41 3505.5 - 4.46E+06 - - - -0.7708 - 2.557 0.503 - 116.3 1 1 0 -0.0014 17 0 0 0 1.99E+08 1.06E+10 - - - 6.5193 1 221125_WJC_METTL3_EV_vs_WT_F04.21826.21826.2 1.40E-11 18/30 R.ETTDTDTADQVIASFK.V "sp|O43707|ACTN4_HUMAN,tr|F5GXS2|F5GXS2_HUMAN,tr|H7C144|H7C144_HUMAN" 3 1740.8054 1.88 54675 21826 2 1740.800951 871.41 Alpha-actinin-4 OS=Homo sapiens OX=9606 GN=ACTN4 PE=1 SV=2 3.84 3506.5 - 2.74E+06 - - - -2.55 - 3.468 0.678 - 1212.2 1 2 0 -0.0044 16 0 0 0 5.46E+07 2.90E+07 - - - 7.1047 0.9996 221125_WJC_METTL3_EV_vs_WT_F04.21827.21827.4 0.000153 Dec-96 R.WVTYFNK[136.11]PDIDAWELR[166.11]K[136.11].G "sp|P20674|COX5A_HUMAN,tr|H3BNX8|H3BNX8_HUMAN,tr|H3BRI0|H3BRI0_HUMAN" 3 2206.1421 1.9 54676 21827 4 2206.134544 552.5428 "Cytochrome c oxidase subunit 5A, mitochondrial OS=Homo sapiens OX=9606 GN=COX5A PE=1 SV=2" 6.12 3506.6 - 2.18E+06 - - - -3.4454 - 2.422 0.43 - 65.1 1 2 0 -0.0076 17 0 0 0 3.70E+07 1.95E+07 - - - 3.2737 0.9999 221125_WJC_METTL3_EV_vs_WT_F04.21828.21828.2 1.04E-10 18/32 K.LATQSNEITIPVTFESR.A "sp|P04792|HSPB1_HUMAN,tr|A0A6Q8PFK8|A0A6Q8PFK8_HUMAN,tr|C9J3N8|C9J3N8_HUMAN,tr|A0A6Q8PGK1|A0A6Q8PGK1_HUMAN" 4 1904.9844 2.62 54677 21828 2 1904.985735 953.4995 Heat shock protein beta-1 OS=Homo sapiens OX=9606 GN=HSPB1 PE=1 SV=2 4.53 3506.7 - 1.04E+06 - - - 0.7234 - 3.763 0.451 - 743 1 2 0 0.0014 17 0 0 0 6.05E+07 2.31E+07 - - - 5.6298 0.9999 221125_WJC_METTL3_EV_vs_WT_F04.21835.21835.3 2.59E-07 13/60 R.ETTDTDTADQVIASFK.V "sp|O43707|ACTN4_HUMAN,tr|F5GXS2|F5GXS2_HUMAN,tr|H7C144|H7C144_HUMAN" 3 1740.8054 7.69 54682 21835 3 1740.801194 581.2757 Alpha-actinin-4 OS=Homo sapiens OX=9606 GN=ACTN4 PE=1 SV=2 3.84 3507.4 - 806358 - - - -2.4104 - 2.395 0.51 - 237.9 1 2 0 -0.0042 16 0 0 0 1.57E+07 2.04E+06 - - - 6.4658 0.9996 221125_WJC_METTL3_EV_vs_WT_F04.21839.21839.3 3.28E-07 15/60 K.IGDEYFTFITDC[160.03]KDPK.A "sp|P49368|TCPG_HUMAN,tr|B4DUR8|B4DUR8_HUMAN" 2 1947.8924 0.31 54684 21839 3 1947.885229 650.3048 T-complex protein 1 subunit gamma OS=Homo sapiens OX=9606 GN=CCT3 PE=1 SV=4 4.23 3507.9 - 1.36E+06 - - - -3.6973 - 2.627 0.604 - 183.4 1 2 1 -0.0072 16 0 0 0 5.69E+07 1.81E+08 - - - 7.7502 1 221125_WJC_METTL3_EV_vs_WT_F04.21840.21840.2 3.53E-12 19/32 L.GNQLDGIHLLDPDVVAR[166.11].F sp|Q86U44|MTA70_HUMAN 1 1840.9671 0 54685 21840 2 1840.960352 921.4908 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 4.41 3508.1 - 1.66E+06 - - - -3.6551 - 3.451 0.709 - 693.3 1 1 0 -0.0067 17 0 0 0 1.97E+06 5.78E+08 - - - 7.3209 1 221125_WJC_METTL3_EV_vs_WT_F04.21842.21842.3 4.00E-06 30/76 K.KLGGSLADSYLDEGFLLDKK.L "sp|P78371|TCPB_HUMAN,tr|F8VQ14|F8VQ14_HUMAN,tr|F5GWF6|F5GWF6_HUMAN" 3 2168.1365 0.5 54687 21842 3 2168.136971 723.7194 T-complex protein 1 subunit beta OS=Homo sapiens OX=9606 GN=CCT2 PE=1 SV=4 4.68 3508.3 - 2.78E+06 - - - 0.2168 - 3.908 0.564 - 694.6 1 2 0 0.0005 20 0 0 0 8.94E+07 1.79E+08 - - - 8.1346 1 221125_WJC_METTL3_EV_vs_WT_F04.21843.21843.4 4.82E-06 21/90 R.DYLHLPPEIVPATLR[166.11]R[166.11].S "sp|P46783|RS10_HUMAN,tr|A0A2R8Y6L3|A0A2R8Y6L3_HUMAN,tr|F6U211|F6U211_HUMAN,tr|A0A1W2PQS6|A0A1W2PQS6_HUMAN,tr|A0A2R8YFH6|A0A2R8YFH6_HUMAN,tr|A0A2R8Y7H1|A0A2R8Y7H1_HUMAN,tr|S4R435|S4R435_HUMAN" 7 1909.0689 1.04 54688 21843 4 1909.066026 478.2745 40S ribosomal protein S10 OS=Homo sapiens OX=9606 GN=RPS10 PE=1 SV=1 6.75 3508.4 - 1.51E+06 - - - -1.4829 - 3.383 0.593 - 326.9 1 2 0 -0.0028 16 0 0 0 1.32E+08 1.27E+08 - - - 4.816 0.9999 221125_WJC_METTL3_EV_vs_WT_F04.21844.21844.3 0.00771 16/64 K.LATQSNEITIPVTFESR.A "sp|P04792|HSPB1_HUMAN,tr|A0A6Q8PFK8|A0A6Q8PFK8_HUMAN,tr|C9J3N8|C9J3N8_HUMAN,tr|A0A6Q8PGK1|A0A6Q8PGK1_HUMAN" 4 1904.9844 1.89 54689 21844 3 1904.98116 636.0021 Heat shock protein beta-1 OS=Homo sapiens OX=9606 GN=HSPB1 PE=1 SV=2 4.53 3508.5 - 1.11E+06 - - - -1.6782 - 2.717 0.431 - 219.7 1 2 0 -0.0032 17 0 0 0 4.40E+07 2.33E+07 - - - 5.8694 0.9998 221125_WJC_METTL3_EV_vs_WT_F04.21845.21845.3 1.72E-06 15/64 K.LATQSNEITIPVTFESR[166.11].A "sp|P04792|HSPB1_HUMAN,tr|A0A6Q8PFK8|A0A6Q8PFK8_HUMAN,tr|C9J3N8|C9J3N8_HUMAN,tr|A0A6Q8PGK1|A0A6Q8PGK1_HUMAN" 4 1914.9926 1.87 54690 21845 3 1914.985615 639.3382 Heat shock protein beta-1 OS=Homo sapiens OX=9606 GN=HSPB1 PE=1 SV=2 4.53 3508.6 - 525116 - - - -3.6616 - 2.779 0.489 - 211 1 2 0 -0.007 17 0 0 0 4.36E+07 2.33E+07 - - - 6.572 1 221125_WJC_METTL3_EV_vs_WT_F04.21848.21848.4 6.94E-11 21/114 K.KLGGSLADSYLDEGFLLDKK.L "sp|P78371|TCPB_HUMAN,tr|F8VQ14|F8VQ14_HUMAN,tr|F5GWF6|F5GWF6_HUMAN" 3 2168.1365 0.47 54691 21848 4 2168.135609 543.0414 T-complex protein 1 subunit beta OS=Homo sapiens OX=9606 GN=CCT2 PE=1 SV=4 4.68 3509 - 5.21E+06 - - - -0.4114 - 3.787 0.604 - 386.1 1 2 0 -0.0009 20 0 0 0 1.50E+08 3.17E+08 - - - 4.9281 1 221125_WJC_METTL3_EV_vs_WT_F04.21851.21851.3 1.30E-07 20/84 K.INFLVNNGGGQFLSPAEHISSK.G "sp|Q9BY49|PECR_HUMAN,tr|B4DJS2|B4DJS2_HUMAN" 2 2328.1862 2.19 54694 21851 3 2328.181427 777.0694 Peroxisomal trans-2-enoyl-CoA reductase OS=Homo sapiens OX=9606 GN=PECR PE=1 SV=2 6.75 3509.3 - 4.18E+06 - - - -2.0694 - 3.847 0.613 - 403.5 1 2 0 -0.0048 22 0 0 0 1.13E+08 5.16E+07 - - - 8.5672 1 221125_WJC_METTL3_EV_vs_WT_F04.21855.21855.3 6.33E-11 24/116 R.GGGFGGGSSFGGGSGFSGGGFGGGGFGGGR.F sp|P35908|K22E_HUMAN 1 2398.0111 70.01 54696 21855 3 2398.007707 800.3443 "Keratin, type II cytoskeletal 2 epidermal OS=Homo sapiens OX=9606 GN=KRT2 PE=1 SV=2" 9.75 3509.8 - 3.65E+06 - - - -1.4291 - 5.02 0.565 - 266.4 1 2 0 -0.0034 30 0 0 0 7.44E+07 1.06E+06 - - - 8.5502 1 221125_WJC_METTL3_EV_vs_WT_F04.21856.21856.2 5.90E-11 15/30 R.ETTDTDTADQVIASFK[136.11].V "sp|O43707|ACTN4_HUMAN,tr|F5GXS2|F5GXS2_HUMAN,tr|H7C144|H7C144_HUMAN" 3 1748.8196 1.86 54697 21856 2 1748.814053 875.4171 Alpha-actinin-4 OS=Homo sapiens OX=9606 GN=ACTN4 PE=1 SV=2 3.84 3509.9 - 1.10E+06 - - - -3.1661 - 3.069 0.665 - 712.5 1 2 0 -0.0055 16 0 0 0 5.46E+07 2.94E+07 - - - 6.7078 1 221125_WJC_METTL3_EV_vs_WT_F04.21857.21857.3 6.71E-09 20/80 Q.AAEEAFVNDIDESSPGTEWER[166.11].V "sp|P09496|CLCA_HUMAN,tr|C9J8P9|C9J8P9_HUMAN" 2 2361.0272 0.68 54698 21857 3 2361.024657 788.0164 Clathrin light chain A OS=Homo sapiens OX=9606 GN=CLTA PE=1 SV=1 3.71 3510 - 3.60E+06 - - - -1.0915 - 3.944 0.635 - 354.8 1 1 0 -0.0026 21 0 0 0 4.89E+07 7.16E+07 - - - 8.9087 1 221125_WJC_METTL3_EV_vs_WT_F04.21858.21858.3 5.46E-09 22/80 Q.AAEEAFVNDIDESSPGTEWER.V "sp|P09496|CLCA_HUMAN,tr|C9J8P9|C9J8P9_HUMAN" 2 2351.019 0.69 54699 21858 3 2351.019345 784.6803 Clathrin light chain A OS=Homo sapiens OX=9606 GN=CLTA PE=1 SV=1 3.71 3510.1 - 2.75E+06 - - - 0.1621 - 3.816 0.646 - 425 1 1 0 0.0004 21 0 0 0 4.89E+07 7.14E+07 - - - 8.9528 0.9998 221125_WJC_METTL3_EV_vs_WT_F04.21859.21859.4 7.64E-06 27/120 R.K[136.11]HAASDVDLEIESLLNQQSTK[136.11].E "sp|Q86U44|MTA70_HUMAN,tr|F5H6D8|F5H6D8_HUMAN,tr|H0YFV6|H0YFV6_HUMAN,tr|B4DTN4|B4DTN4_HUMAN" 4 2341.2096 0 54700 21859 4 2341.201502 586.3097 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 4.75 3510.2 - 2.30E+06 - - - -3.467 - 3.838 0.464 - 495.1 1 2 0 -0.0081 21 0 0 0 2.93E+05 8.38E+07 - - - 3.7071 1 221125_WJC_METTL3_EV_vs_WT_F04.21860.21860.4 0.000615 26/90 R.DYLHLPPEIVPATLRR.S "sp|P46783|RS10_HUMAN,tr|A0A2R8Y6L3|A0A2R8Y6L3_HUMAN,tr|F6U211|F6U211_HUMAN,tr|A0A1W2PQS6|A0A1W2PQS6_HUMAN,tr|A0A2R8YFH6|A0A2R8YFH6_HUMAN,tr|A0A2R8Y7H1|A0A2R8Y7H1_HUMAN,tr|S4R435|S4R435_HUMAN" 7 1889.0523 1.04 54701 21860 4 1889.046751 473.2704 40S ribosomal protein S10 OS=Homo sapiens OX=9606 GN=RPS10 PE=1 SV=1 6.75 3510.4 - 1.61E+06 - - - -2.9465 - 3.97 0.576 - 471 1 2 0 -0.0056 16 0 0 0 1.33E+08 1.29E+08 - - - 4.7236 1 221125_WJC_METTL3_EV_vs_WT_F04.21866.21866.3 3.89E-12 17/76 K.GNPQGFNQGLDC[160.03]DVIVAEVR[166.11].S sp|Q86U44|MTA70_HUMAN 1 2197.0461 0.01 54705 21866 3 2198.04293 733.356 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 4.03 3511.1 - 8.21E+06 - - - 453.6973 - 3.231 0.665 - 316.3 1 2 0 0.9968 20 0 0 0 4.75E+06 3.38E+08 - - - 8.5232 0.9999 221125_WJC_METTL3_EV_vs_WT_F04.21868.21868.4 4.95E-08 17/114 K.K[136.11]LGGSLADSYLDEGFLLDK[136.11]K[136.11].L "sp|P78371|TCPB_HUMAN,tr|F8VQ14|F8VQ14_HUMAN,tr|F5GWF6|F5GWF6_HUMAN" 3 2192.1791 0.47 54707 21868 4 2192.173611 549.0521 T-complex protein 1 subunit beta OS=Homo sapiens OX=9606 GN=CCT2 PE=1 SV=4 4.68 3511.2 - 2.46E+07 - - - -2.5044 - 2.96 0.511 - 244.6 1 2 0 -0.0055 20 0 0 0 1.50E+08 3.18E+08 - - - 4.035 1 221125_WJC_METTL3_EV_vs_WT_F04.21871.21871.2 3.86E-15 24/48 K.IDSIPHLNNSTPLVDPSVYGYGVQK.R sp|Q96I24|FUBP3_HUMAN 1 2712.3759 2.74 54708 21871 2 2712.369408 1357.1952 Far upstream element-binding protein 3 OS=Homo sapiens OX=9606 GN=FUBP3 PE=1 SV=2 5.21 3511.6 - 1.47E+06 - - - -2.392 - 3.947 0.71 - 808.1 1 2 0 -0.0065 25 0 0 0 3.88E+07 1.41E+07 - - - 7.6585 1 221125_WJC_METTL3_EV_vs_WT_F04.21873.21873.2 3.57E-11 19/40 Q.AAEEAFVNDIDESSPGTEWER[166.11].V "sp|P09496|CLCA_HUMAN,tr|C9J8P9|C9J8P9_HUMAN" 2 2361.0272 0.86 54709 21873 2 2361.023174 1181.5209 Clathrin light chain A OS=Homo sapiens OX=9606 GN=CLTA PE=1 SV=1 3.71 3511.8 - 1.07E+06 - - - -1.7196 - 4.107 0.712 - 944.4 1 1 0 -0.0041 21 0 0 0 1.54E+07 1.79E+07 - - - 7.7717 1 221125_WJC_METTL3_EV_vs_WT_F04.21876.21876.3 4.36E-13 23/76 K.K[136.11]LGGSLADSYLDEGFLLDK[136.11]K[136.11].L "sp|P78371|TCPB_HUMAN,tr|F8VQ14|F8VQ14_HUMAN,tr|F5GWF6|F5GWF6_HUMAN" 3 2192.1791 0.5 54711 21876 3 2192.182164 731.7336 T-complex protein 1 subunit beta OS=Homo sapiens OX=9606 GN=CCT2 PE=1 SV=4 4.68 3512.1 - 9.23E+06 - - - 1.3972 - 4.314 0.641 - 648.4 1 2 0 0.0031 20 0 0 0 8.94E+07 1.79E+08 - - - 9.2322 1 221125_WJC_METTL3_EV_vs_WT_F04.21877.21877.3 1.49E-07 14/64 K.LATQSNEITIPVTFESR[166.11].A "sp|P04792|HSPB1_HUMAN,tr|A0A6Q8PFK8|A0A6Q8PFK8_HUMAN,tr|C9J3N8|C9J3N8_HUMAN,tr|A0A6Q8PGK1|A0A6Q8PGK1_HUMAN" 4 1914.9926 1.87 54712 21877 3 1914.991472 639.3382 Heat shock protein beta-1 OS=Homo sapiens OX=9606 GN=HSPB1 PE=1 SV=2 4.53 3512.2 - 1.07E+06 - - - -0.6031 - 3.025 0.564 - 178.5 1 2 0 -0.0012 17 0 0 0 4.36E+07 2.33E+07 - - - 7.6241 0.9594 221125_WJC_METTL3_EV_vs_WT_F04.21881.21881.3 5.05E-10 17/64 L.GNQLDGIHLLDPDVVAR.F sp|Q86U44|MTA70_HUMAN 1 1830.9588 0.02 54714 21881 3 1831.959738 611.3269 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 4.41 3512.7 - 5.06E+06 - - - 546.6682 - 3.238 0.602 - 330.3 1 1 0 1.0009 17 0 0 0 1.99E+08 1.06E+10 - - - 7.9427 0.9992 221125_WJC_METTL3_EV_vs_WT_F04.21885.21885.3 1.54E-05 23/80 R.K[136.11]HAASDVDLEIESLLNQQSTK[136.11].E "sp|Q86U44|MTA70_HUMAN,tr|F5H6D8|F5H6D8_HUMAN,tr|H0YFV6|H0YFV6_HUMAN,tr|B4DTN4|B4DTN4_HUMAN" 4 2341.2096 1.16 54716 21885 3 2342.208383 781.4105 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 4.75 3513.2 - 3.53E+06 - - - 426.6017 - 3.691 0.537 - 715.4 1 2 0 0.9988 21 0 0 0 7.94E+07 6.86E+07 - - - 7.3812 0.9999 221125_WJC_METTL3_EV_vs_WT_F04.21890.21890.3 3.23E-09 18/72 K.EIEELKQELIQAEIQNGVK.Q "sp|Q12904|AIMP1_HUMAN,tr|A0A804HJ47|A0A804HJ47_HUMAN,tr|D6R937|D6R937_HUMAN,tr|A0A5F9ZHC5|A0A5F9ZHC5_HUMAN" 4 2210.1794 0.78 54718 21890 3 2210.181428 737.7338 Aminoacyl tRNA synthase complex-interacting multifunctional protein 1 OS=Homo sapiens OX=9606 GN=AIMP1 PE=1 SV=2 4.33 3513.9 - 5.72E+06 - - - 0.9049 - 3.084 0.542 - 417.7 1 2 1 0.002 19 0 0 0 5.77E+07 7.39E+07 - - - 7.3491 1 221125_WJC_METTL3_EV_vs_WT_F04.21892.21892.4 3.85E-09 21/102 K.K[136.11]VPEFQFLIGDEAATHLK[136.11].Q "sp|P34949|MPI_HUMAN,tr|H3BPB8|H3BPB8_HUMAN,tr|H3BP57|H3BP57_HUMAN,tr|H3BT48|H3BT48_HUMAN,tr|H3BU66|H3BU66_HUMAN,tr|H3BQX0|H3BQX0_HUMAN,tr|H3BUZ9|H3BUZ9_HUMAN,tr|H3BPM5|H3BPM5_HUMAN,tr|H3BPP3|H3BPP3_HUMAN,tr|F5GX71|F5GX71_HUMAN,tr|H3BMZ9|H3BMZ9_HUMAN,tr|H3BNY8|H3BNY8_HUMAN" 12 2058.1121 1.67 54720 21892 4 2058.107659 515.5353 Mannose-6-phosphate isomerase OS=Homo sapiens OX=9606 GN=MPI PE=1 SV=2 5.45 3514.1 - 2.11E+06 - - - -2.1466 - 3.195 0.55 - 390.8 1 2 0 -0.0044 18 0 0 0 3.82E+07 2.28E+07 - - - 4.4099 1 221125_WJC_METTL3_EV_vs_WT_F04.21893.21893.4 9.48E-07 25/84 R.GIEKPPFELPDFIKR.T "sp|Q13435|SF3B2_HUMAN,tr|E9PPJ0|E9PPJ0_HUMAN" 2 1784.9825 1.15 54721 21893 4 1784.979474 447.2529 Splicing factor 3B subunit 2 OS=Homo sapiens OX=9606 GN=SF3B2 PE=1 SV=2 6.18 3514.2 - 1.32E+06 - - - -1.6986 - 3.715 0.535 - 549.6 1 2 0 -0.003 15 0 0 0 3.06E+07 2.66E+07 - - - 4.3514 1 221125_WJC_METTL3_EV_vs_WT_F04.21894.21894.4 1.55E-09 22/84 R.GIEK[136.11]PPFELPDFIK[136.11]R[166.11].T "sp|Q13435|SF3B2_HUMAN,tr|E9PPJ0|E9PPJ0_HUMAN" 2 1811.0192 1.15 54722 21894 4 1811.018128 453.7621 Splicing factor 3B subunit 2 OS=Homo sapiens OX=9606 GN=SF3B2 PE=1 SV=2 6.18 3514.4 - 924003 - - - -0.5787 - 3.42 0.573 - 282.6 1 2 0 -0.001 15 0 0 0 3.06E+07 2.66E+07 - - - 4.6531 0.9993 221125_WJC_METTL3_EV_vs_WT_F04.21896.21896.2 0.0444 14-Jul K.DVIEEYFK.C sp|P25398|RS12_HUMAN 1 1041.5019 2.76 54724 21896 2 1041.502966 521.7582 40S ribosomal protein S12 OS=Homo sapiens OX=9606 GN=RPS12 PE=1 SV=3 4.14 3514.6 - 436633 - - - 1.0446 - 1.522 0.356 - 102.1 1 2 0 0.0011 8 0 0 0 1.01E+07 3.66E+06 - - - 2.9369 0.9999 221125_WJC_METTL3_EV_vs_WT_F04.21899.21899.3 5.69E-11 29/72 R.IQEIIEQLDVTTSEYEK[136.11]EK[136.11].L "sp|P10809|CH60_HUMAN,tr|A0A7I2V2X6|A0A7I2V2X6_HUMAN,tr|A0A7I2YQK6|A0A7I2YQK6_HUMAN,tr|A0A7I2V599|A0A7I2V599_HUMAN" 4 2310.1813 1.43 54725 21899 3 2310.17592 771.0677 "60 kDa heat shock protein, mitochondrial OS=Homo sapiens OX=9606 GN=HSPD1 PE=1 SV=2" 4.14 3515 - 1.27E+07 - - - -2.3457 - 4.409 0.55 - 1281.4 1 2 1 -0.0054 19 0 0 0 1.35E+10 9.50E+09 - - - 8.3155 1 221125_WJC_METTL3_EV_vs_WT_F04.21900.21900.3 2.29E-07 25/72 R.IQEIIEQLDVTTSEYEKEK.L "sp|P10809|CH60_HUMAN,tr|A0A7I2V2X6|A0A7I2V2X6_HUMAN,tr|A0A7I2YQK6|A0A7I2YQK6_HUMAN,tr|A0A7I2V599|A0A7I2V599_HUMAN" 4 2294.1529 1.43 54726 21900 3 2294.152025 765.7249 "60 kDa heat shock protein, mitochondrial OS=Homo sapiens OX=9606 GN=HSPD1 PE=1 SV=2" 4.14 3515 - 1.13E+07 - - - -0.3984 - 4.265 0.58 - 807.1 1 2 1 -0.0009 19 0 0 0 1.35E+10 9.50E+09 - - - 8.5696 1 221125_WJC_METTL3_EV_vs_WT_F04.21901.21901.4 1.54E-08 19/102 K.KVPEFQFLIGDEAATHLK.Q "sp|P34949|MPI_HUMAN,tr|H3BPB8|H3BPB8_HUMAN,tr|H3BP57|H3BP57_HUMAN,tr|H3BT48|H3BT48_HUMAN,tr|H3BU66|H3BU66_HUMAN,tr|H3BQX0|H3BQX0_HUMAN,tr|H3BUZ9|H3BUZ9_HUMAN,tr|H3BPM5|H3BPM5_HUMAN,tr|H3BPP3|H3BPP3_HUMAN,tr|F5GX71|F5GX71_HUMAN,tr|H3BMZ9|H3BMZ9_HUMAN,tr|H3BNY8|H3BNY8_HUMAN" 12 2042.0837 1.67 54727 21901 4 2042.080267 511.5282 Mannose-6-phosphate isomerase OS=Homo sapiens OX=9606 GN=MPI PE=1 SV=2 5.45 3515.1 - 2.99E+06 - - - -1.6699 - 3.314 0.547 - 261.4 1 2 0 -0.0034 18 0 0 0 3.82E+07 2.28E+07 - - - 4.3966 1 221125_WJC_METTL3_EV_vs_WT_F04.21903.21903.3 1.16E-06 20/56 K.TLSSVQNEVQEALQR.A sp|P12270|TPR_HUMAN 1 1700.8693 3.31 54729 21903 3 1700.866952 567.9637 Nucleoprotein TPR OS=Homo sapiens OX=9606 GN=TPR PE=1 SV=3 4.53 3515.4 - 2.04E+06 - - - -1.3963 - 2.869 0.513 - 508.1 1 2 0 -0.0024 15 0 0 0 7.39E+07 2.23E+07 - - - 7.009 0.995 221125_WJC_METTL3_EV_vs_WT_F04.21904.21904.3 2.18E-06 18/56 N.QLDGIHLLDPDVVAR[166.11].F sp|Q86U44|MTA70_HUMAN 1 1669.9027 3.43 54730 21904 3 1669.900571 557.6415 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 4.41 3515.5 - 928360 - - - -1.2689 - 2.792 0.439 - 394 1 1 0 -0.0021 15 0 0 0 3.65E+07 1.06E+07 - - - 6.113 1 221125_WJC_METTL3_EV_vs_WT_F04.21905.21905.2 9.10E-17 18/36 F.TTYSDNQPGVLIQVYEGER[166.11].A "sp|P0DMV8|HS71A_HUMAN,sp|P34931|HS71L_HUMAN,sp|P11142|HSP7C_HUMAN,sp|P0DMV9|HS71B_HUMAN,tr|E9PNE6|E9PNE6_HUMAN,tr|A8K7Q2|A8K7Q2_HUMAN,tr|E9PKE3|E9PKE3_HUMAN,tr|E9PS65|E9PS65_HUMAN,tr|Q53FA3|Q53FA3_HUMAN,tr|V9GZ37|V9GZ37_HUMAN,tr|A0A0G2JIW1|A0A0G2JIW1_HUMAN" 11 2178.0468 0.03 54731 21905 2 2178.045939 1090.0307 Heat shock 70 kDa protein 1A OS=Homo sapiens OX=9606 GN=HSPA1A PE=1 SV=1 4.14 3515.6 - 851228 - - - -0.4169 - 3.666 0.738 - 583.3 1 1 0 -0.0009 19 0 0 0 1.97E+06 6.50E+07 - - - 7.6855 0.9995 221125_WJC_METTL3_EV_vs_WT_F04.21912.21912.4 0.0063 16/144 K.IDSIPHLNNSTPLVDPSVYGYGVQK[136.11].R sp|Q96I24|FUBP3_HUMAN 1 2720.3901 1.75 54736 21912 4 2720.387699 681.1048 Far upstream element-binding protein 3 OS=Homo sapiens OX=9606 GN=FUBP3 PE=1 SV=2 5.21 3516.4 - 4.74E+06 - - - -0.8811 - 2.604 0.325 - 106.4 1 2 0 -0.0024 25 0 0 0 1.64E+08 9.38E+07 - - - 2.3586 0.9993 221125_WJC_METTL3_EV_vs_WT_F04.21916.21916.3 4.80E-07 18/48 R.SQLIDELADK[136.11]FNR[166.11].L sp|Q8N3U4|STAG2_HUMAN 1 1565.8168 0.95 54738 21916 3 1565.810062 522.9462 Cohesin subunit SA-2 OS=Homo sapiens OX=9606 GN=STAG2 PE=1 SV=3 4.56 3516.9 - 1.17E+06 - - - -4.3294 - 3.247 0.516 - 557.3 1 2 1 -0.0068 13 0 0 0 2.02E+07 2.13E+07 - - - 7.4842 1 221125_WJC_METTL3_EV_vs_WT_F04.21919.21919.4 6.85E-22 41/186 R.PAPVAVAAAATAAAYGGYPTAHTATDYGYTQR.Q sp|Q96KR1|ZFR_HUMAN 1 3153.5156 1.03 54741 21919 4 3153.516132 789.3862 Zinc finger RNA-binding protein OS=Homo sapiens OX=9606 GN=ZFR PE=1 SV=2 7.15 3517.1 - 3.05E+06 - - - 0.1757 - 6.452 0.77 - 1215.7 1 1 0 0.0006 32 0 0 0 5.37E+07 5.23E+07 - - - 6.4909 1 221125_WJC_METTL3_EV_vs_WT_F04.21920.21920.3 9.75E-06 20/60 R.DYLHLPPEIVPATLR[166.11]R[166.11].S "sp|P46783|RS10_HUMAN,tr|A0A2R8Y6L3|A0A2R8Y6L3_HUMAN,tr|F6U211|F6U211_HUMAN,tr|A0A1W2PQS6|A0A1W2PQS6_HUMAN,tr|A0A2R8YFH6|A0A2R8YFH6_HUMAN,tr|A0A2R8Y7H1|A0A2R8Y7H1_HUMAN,tr|S4R435|S4R435_HUMAN" 7 1909.0689 1.05 54742 21920 3 1909.065633 637.3636 40S ribosomal protein S10 OS=Homo sapiens OX=9606 GN=RPS10 PE=1 SV=1 6.75 3517.2 - 1.09E+06 - - - -1.6888 - 3.136 0.556 - 400.1 1 2 0 -0.0032 16 0 0 0 5.68E+07 5.43E+07 - - - 7.6706 1 221125_WJC_METTL3_EV_vs_WT_F04.21921.21921.2 4.64E-09 20/36 R.IQEIIEQLDVTTSEYEK[136.11]EK[136.11].L "sp|P10809|CH60_HUMAN,tr|A0A7I2V2X6|A0A7I2V2X6_HUMAN,tr|A0A7I2YQK6|A0A7I2YQK6_HUMAN,tr|A0A7I2V599|A0A7I2V599_HUMAN" 4 2310.1813 1.38 54743 21921 2 2310.175899 1156.0979 "60 kDa heat shock protein, mitochondrial OS=Homo sapiens OX=9606 GN=HSPD1 PE=1 SV=2" 4.14 3517.4 - 1.04E+06 - - - -2.3548 - 4.15 0.659 - 972.1 1 2 1 -0.0054 19 0 0 0 3.36E+08 2.44E+08 - - - 7.4054 1 221125_WJC_METTL3_EV_vs_WT_F04.21924.21924.3 1.06E-08 20/76 K.GQLNADEISLRPAQSFLMNK.N "sp|P78344|IF4G2_HUMAN,tr|D3DQV9|D3DQV9_HUMAN" 2 2231.1369 0.94 54744 21924 3 2231.134387 744.7196 Eukaryotic translation initiation factor 4 gamma 2 OS=Homo sapiens OX=9606 GN=EIF4G2 PE=1 SV=1 6.07 3517.7 - 3.11E+06 - - - -1.1048 - 3.612 0.394 - 333.6 1 2 0 -0.0025 20 0 0 0 7.85E+07 8.36E+07 - - - 6.0477 1 221125_WJC_METTL3_EV_vs_WT_F04.21925.21925.2 3.45E-10 23/36 R.IQEIIEQLDVTTSEYEKEK.L "sp|P10809|CH60_HUMAN,tr|A0A7I2V2X6|A0A7I2V2X6_HUMAN,tr|A0A7I2YQK6|A0A7I2YQK6_HUMAN,tr|A0A7I2V599|A0A7I2V599_HUMAN" 4 2294.1529 1.38 54745 21925 2 2294.150934 1148.0837 "60 kDa heat shock protein, mitochondrial OS=Homo sapiens OX=9606 GN=HSPD1 PE=1 SV=2" 4.14 3517.9 - 3.45E+06 - - - -0.874 - 4.329 0.653 - 1305.1 1 2 1 -0.002 19 0 0 0 3.36E+08 2.44E+08 - - - 7.466 0.9998 221125_WJC_METTL3_EV_vs_WT_F04.21926.21926.3 0.000145 17/76 R.AINVLLEGNPDTHSWEMVGK.K "sp|Q14157|UBP2L_HUMAN,tr|Q5VU78|Q5VU78_HUMAN,tr|F8W726|F8W726_HUMAN,tr|Q5VU81|Q5VU81_HUMAN,tr|Q5VU79|Q5VU79_HUMAN,tr|Q5VU80|Q5VU80_HUMAN,tr|Q5VU77|Q5VU77_HUMAN" 7 2209.0838 5.75 54746 21926 3 2209.076574 737.3685 Ubiquitin-associated protein 2-like OS=Homo sapiens OX=9606 GN=UBAP2L PE=1 SV=2 4.65 3517.9 - 2.33E+06 - - - -3.2502 - 2.765 0.472 - 359.6 1 2 0 -0.0072 20 0 0 0 4.53E+07 7.86E+06 - - - 6.2677 0.9999 221125_WJC_METTL3_EV_vs_WT_F04.21929.21929.3 1.44E-05 14/56 K.TLSSVQNEVQEALQR[166.11].A sp|P12270|TPR_HUMAN 1 1710.8776 3.31 54748 21929 3 1710.873449 571.2998 Nucleoprotein TPR OS=Homo sapiens OX=9606 GN=TPR PE=1 SV=3 4.53 3518.3 - 1.26E+06 - - - -2.4245 - 2.564 0.494 - 272.3 1 2 0 -0.0041 15 0 0 0 7.39E+07 2.23E+07 - - - 6.5034 0.9979 221125_WJC_METTL3_EV_vs_WT_F04.21933.21933.4 1.76E-06 13/144 K.IDSIPHLNNSTPLVDPSVYGYGVQK.R sp|Q96I24|FUBP3_HUMAN 1 2712.3759 1.75 54751 21933 4 2712.359455 679.1013 Far upstream element-binding protein 3 OS=Homo sapiens OX=9606 GN=FUBP3 PE=1 SV=2 5.21 3518.6 - 3.17E+06 - - - -6.0615 - 2.904 0.436 - 76.5 1 2 0 -0.0164 25 0 0 0 1.64E+08 9.38E+07 - - - 3.3555 1 221125_WJC_METTL3_EV_vs_WT_F04.21934.21934.4 8.93E-15 32/186 R.PAPVAVAAAATAAAYGGYPTAHTATDYGYTQR[166.11].Q sp|Q96KR1|ZFR_HUMAN 1 3163.5238 1.03 54752 21934 4 3163.517946 791.8882 Zinc finger RNA-binding protein OS=Homo sapiens OX=9606 GN=ZFR PE=1 SV=2 7.15 3518.7 - 2.79E+06 - - - -1.8656 - 4.923 0.722 - 632.8 1 1 0 -0.0059 32 0 0 0 5.37E+07 5.23E+07 - - - 5.9899 0.9999 221125_WJC_METTL3_EV_vs_WT_F04.21943.21943.3 2.04E-07 18/48 R.SQLIDELADKFNR.L sp|Q8N3U4|STAG2_HUMAN 1 1547.7944 0.95 54759 21943 3 1547.793033 516.9387 Cohesin subunit SA-2 OS=Homo sapiens OX=9606 GN=STAG2 PE=1 SV=3 4.56 3519.6 - 1.79E+06 - - - -0.8645 - 3.464 0.491 - 612.7 1 2 1 -0.0013 13 0 0 0 2.02E+07 2.13E+07 - - - 7.3824 1 221125_WJC_METTL3_EV_vs_WT_F04.21950.21950.2 1.23E-11 20/38 K.YAGSALQYEDVSTAVQNLQK[136.11].A "sp|Q9NP79|VTA1_HUMAN,tr|Q5TGM0|Q5TGM0_HUMAN,tr|A0A087WY55|A0A087WY55_HUMAN" 3 2192.0841 2.31 54763 21950 2 2192.077432 1097.0493 Vacuolar protein sorting-associated protein VTA1 homolog OS=Homo sapiens OX=9606 GN=VTA1 PE=1 SV=1 4.37 3520.5 - 1.03E+06 - - - -3.0318 - 4.239 0.696 - 1657.9 1 2 0 -0.0066 20 0 0 0 6.85E+07 2.97E+07 - - - 7.7305 1 221125_WJC_METTL3_EV_vs_WT_F04.21954.21954.2 3.06E-15 18/38 K.YAGSALQYEDVSTAVQNLQK.A "sp|Q9NP79|VTA1_HUMAN,tr|Q5TGM0|Q5TGM0_HUMAN,tr|A0A087WY55|A0A087WY55_HUMAN" 3 2184.0699 2.33 54767 21954 2 2184.065654 1093.0422 Vacuolar protein sorting-associated protein VTA1 homolog OS=Homo sapiens OX=9606 GN=VTA1 PE=1 SV=1 4.37 3520.9 - 1.88E+06 - - - -1.934 - 4.05 0.7 - 882.9 1 2 0 -0.0042 20 0 0 0 6.92E+07 2.97E+07 - - - 7.6487 0.9986 221125_WJC_METTL3_EV_vs_WT_F04.21958.21958.3 3.92E-08 20/72 F.TTYSDNQPGVLIQVYEGER[166.11].A "sp|P0DMV8|HS71A_HUMAN,sp|P34931|HS71L_HUMAN,sp|P11142|HSP7C_HUMAN,sp|P0DMV9|HS71B_HUMAN,tr|E9PNE6|E9PNE6_HUMAN,tr|A8K7Q2|A8K7Q2_HUMAN,tr|E9PKE3|E9PKE3_HUMAN,tr|E9PS65|E9PS65_HUMAN,tr|Q53FA3|Q53FA3_HUMAN,tr|V9GZ37|V9GZ37_HUMAN,tr|A0A0G2JIW1|A0A0G2JIW1_HUMAN" 11 2178.0468 0.21 54769 21958 3 2178.043252 727.0229 Heat shock 70 kDa protein 1A OS=Homo sapiens OX=9606 GN=HSPA1A PE=1 SV=1 4.14 3521.4 - 9.36E+06 - - - -1.6506 - 3.445 0.611 - 499.7 1 1 0 -0.0036 19 0 0 0 5.76E+07 2.80E+08 - - - 8.3899 0.9059 221125_WJC_METTL3_EV_vs_WT_F04.21964.21964.3 0.0638 Nov-76 R.GFAFVTFDDHDTVDKIVVQK.Y "sp|P51991|ROA3_HUMAN,tr|A0A7I2V5D8|A0A7I2V5D8_HUMAN,tr|A0A7I2V2R3|A0A7I2V2R3_HUMAN,tr|A0A7I2V4J6|A0A7I2V4J6_HUMAN,tr|A0A7I2V4G0|A0A7I2V4G0_HUMAN" 5 2280.1426 0.23 54773 21964 3 2281.141707 761.0548 Heterogeneous nuclear ribonucleoprotein A3 OS=Homo sapiens OX=9606 GN=HNRNPA3 PE=1 SV=2 4.56 3522 - 6.15E+06 - - - 438.1559 - 2.167 0.335 - 91.7 1 2 1 0.9991 20 0 0 0 1.43E+08 6.31E+08 - - - 3.8743 0.9995 221125_WJC_METTL3_EV_vs_WT_F04.21967.21967.2 0.000141 16-Nov K.LLQDFFNGR[166.11].D "sp|P0DMV8|HS71A_HUMAN,sp|P0DMV9|HS71B_HUMAN,tr|V9GZ37|V9GZ37_HUMAN,tr|A0A0G2JIW1|A0A0G2JIW1_HUMAN" 4 1118.5748 5.26 54776 21967 2 1118.572264 560.2947 Heat shock 70 kDa protein 1A OS=Homo sapiens OX=9606 GN=HSPA1A PE=1 SV=1 5.84 3522.4 - 1.76E+06 - - - -2.2788 - 2.29 0.357 - 340.3 1 2 0 -0.0026 9 0 0 0 2.35E+08 4.47E+07 - - - 4.074 1 221125_WJC_METTL3_EV_vs_WT_F04.21972.21972.3 3.48E-13 21/76 K.YAGSALQYEDVSTAVQNLQK[136.11].A "sp|Q9NP79|VTA1_HUMAN,tr|Q5TGM0|Q5TGM0_HUMAN,tr|A0A087WY55|A0A087WY55_HUMAN" 3 2192.0841 1.94 54779 21972 3 2192.080094 731.702 Vacuolar protein sorting-associated protein VTA1 homolog OS=Homo sapiens OX=9606 GN=VTA1 PE=1 SV=1 4.37 3522.9 - 9.18E+06 - - - -1.8174 - 3.898 0.681 - 655.4 1 2 0 -0.004 20 0 0 0 2.37E+08 1.22E+08 - - - 9.4319 1 221125_WJC_METTL3_EV_vs_WT_F04.21974.21974.4 2.70E-05 17/126 R.APDELHYTYLDTFGRPVIVAYK.K "sp|P04843|RPN1_HUMAN,tr|B7Z4L4|B7Z4L4_HUMAN" 2 2567.306 1.62 54781 21974 4 2567.304841 642.8338 Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit 1 OS=Homo sapiens OX=9606 GN=RPN1 PE=1 SV=1 5.38 3523 - 3.55E+06 - - - -0.4616 - 3.052 0.476 - 178.3 1 2 0 -0.0012 22 0 0 0 3.70E+07 2.28E+07 - - - 3.7339 1 221125_WJC_METTL3_EV_vs_WT_F04.21979.21979.4 4.89E-12 19/114 R.GFAFVTFDDHDTVDKIVVQK.Y "sp|P51991|ROA3_HUMAN,tr|A0A7I2V5D8|A0A7I2V5D8_HUMAN,tr|A0A7I2V2R3|A0A7I2V2R3_HUMAN,tr|A0A7I2V4J6|A0A7I2V4J6_HUMAN,tr|A0A7I2V4G0|A0A7I2V4G0_HUMAN" 5 2280.1426 0.81 54784 21979 4 2280.14054 571.0429 Heterogeneous nuclear ribonucleoprotein A3 OS=Homo sapiens OX=9606 GN=HNRNPA3 PE=1 SV=2 4.56 3523.6 - 9.98E+06 - - - -0.9249 - 3.365 0.67 - 173.4 1 2 1 -0.0021 20 0 0 0 7.79E+07 9.59E+07 - - - 5.4628 1 221125_WJC_METTL3_EV_vs_WT_F04.21980.21980.4 2.65E-12 20/126 R.APDELHYTYLDTFGR[166.11]PVIVAYK[136.11].K "sp|P04843|RPN1_HUMAN,tr|B7Z4L4|B7Z4L4_HUMAN" 2 2585.3285 1.62 54785 21980 4 2585.322409 647.3394 Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit 1 OS=Homo sapiens OX=9606 GN=RPN1 PE=1 SV=1 5.38 3523.7 - 2.89E+06 - - - -2.3544 - 3.796 0.591 - 247.8 1 2 0 -0.0061 22 0 0 0 3.70E+07 2.28E+07 - - - 4.8049 0.9999 221125_WJC_METTL3_EV_vs_WT_F04.21987.21987.3 3.70E-05 19/52 K.AQNDLIWNIKDELK.K "sp|P09874|PARP1_HUMAN,tr|A0A7I2V5E9|A0A7I2V5E9_HUMAN,tr|A0A7I2V625|A0A7I2V625_HUMAN,tr|A0A7I2V3E1|A0A7I2V3E1_HUMAN" 4 1698.8941 0.98 54790 21987 3 1698.893718 567.3053 Poly [ADP-ribose] polymerase 1 OS=Homo sapiens OX=9606 GN=PARP1 PE=1 SV=4 4.56 3524.6 - 2.45E+06 - - - -0.216 - 3.404 0.524 - 694.6 1 2 1 -0.0004 14 0 0 0 3.28E+07 3.35E+07 - - - 7.6373 1 221125_WJC_METTL3_EV_vs_WT_F04.21988.21988.3 2.62E-08 23/84 K.AAAIGIDLGTTYSC[160.03]VGVFQHGK[136.11].V "sp|P0DMV8|HS71A_HUMAN,sp|P0DMV9|HS71B_HUMAN,tr|V9GZ37|V9GZ37_HUMAN,tr|A0A0G2JIW1|A0A0G2JIW1_HUMAN" 4 2272.1402 0.13 54791 21988 3 2272.140254 758.3873 Heat shock 70 kDa protein 1A OS=Homo sapiens OX=9606 GN=HSPA1A PE=1 SV=1 6.78 3524.6 - 8.92E+06 - - - 0.0445 - 3.743 0.643 - 579.8 2 2 0 0.0001 22 0 0 0 1.52E+08 1.13E+09 - - - 8.6987 1 221125_WJC_METTL3_EV_vs_WT_F04.21990.21990.2 1.44E-11 18/32 K.YSDVSGLLANYTDPQSK.L "sp|Q6PI98|IN80C_HUMAN,tr|M0R3E2|M0R3E2_HUMAN,tr|K7EIY8|K7EIY8_HUMAN" 3 1856.8792 1.99 54793 21990 2 1856.883474 929.4469 INO80 complex subunit C OS=Homo sapiens OX=9606 GN=INO80C PE=1 SV=1 4.21 3524.9 - 829560 - - - 2.2893 - 3.311 0.669 - 747.7 1 2 0 0.0043 17 0 0 0 2.34E+07 1.17E+07 - - - 6.9244 1 221125_WJC_METTL3_EV_vs_WT_F04.21993.21993.3 6.85E-07 21/84 K.AAAIGIDLGTTYSC[160.03]VGVFQHGK.V "sp|P0DMV8|HS71A_HUMAN,sp|P0DMV9|HS71B_HUMAN,tr|V9GZ37|V9GZ37_HUMAN,tr|A0A0G2JIW1|A0A0G2JIW1_HUMAN" 4 2264.126 0.14 54794 21993 3 2264.125302 755.7159 Heat shock 70 kDa protein 1A OS=Homo sapiens OX=9606 GN=HSPA1A PE=1 SV=1 6.78 3525.4 - 2.60E+06 - - - -0.2875 - 3.421 0.569 - 398.8 1 2 0 -0.0007 22 0 0 0 1.59E+08 1.14E+09 - - - 7.7996 1 221125_WJC_METTL3_EV_vs_WT_F04.21994.21994.3 1.55E-08 20/60 R.EFPDVLEC[160.03]TVSHAVEK.L sp|P48507|GSH0_HUMAN 1 1858.8771 1.27 54795 21994 3 1858.880657 620.633 Glutamate--cysteine ligase regulatory subunit OS=Homo sapiens OX=9606 GN=GCLM PE=1 SV=1 4.4 3525.5 - 1.75E+06 - - - 1.9055 - 3.35 0.529 - 438.2 1 2 0 0.0035 16 0 0 0 2.36E+07 1.86E+07 - - - 7.5389 0.9999 221125_WJC_METTL3_EV_vs_WT_F04.22000.22000.3 2.29E-09 17/60 R.EFPDVLEC[160.03]TVSHAVEK[136.11].L sp|P48507|GSH0_HUMAN 1 1866.8913 1.27 54801 22000 3 1866.889762 623.3044 Glutamate--cysteine ligase regulatory subunit OS=Homo sapiens OX=9606 GN=GCLM PE=1 SV=1 4.4 3526.2 - 1.01E+06 - - - -0.8319 - 3.029 0.353 - 338.6 1 2 0 -0.0016 16 0 0 0 2.36E+07 1.86E+07 - - - 5.3187 0.9999 221125_WJC_METTL3_EV_vs_WT_F04.22002.22002.3 0.000146 14/64 R.SALQSINEWAAQTTDGK[136.11].L "sp|P50454|SERPH_HUMAN,tr|E9PNX1|E9PNX1_HUMAN,tr|E9PPV6|E9PPV6_HUMAN,tr|E9PR70|E9PR70_HUMAN,tr|E9PMI5|E9PMI5_HUMAN,tr|E9PJH8|E9PJH8_HUMAN,tr|E9PK86|E9PK86_HUMAN,tr|E9PQ34|E9PQ34_HUMAN" 8 1826.889 3.2 54803 22002 3 1826.886741 609.9703 Serpin H1 OS=Homo sapiens OX=9606 GN=SERPINH1 PE=1 SV=2 4.37 3526.4 - 659859 - - - -1.2404 - 2.141 0.412 - 191.8 1 2 0 -0.0023 17 0 0 0 1.75E+07 5.48E+06 - - - 5.056 1 221125_WJC_METTL3_EV_vs_WT_F04.22006.22006.3 2.65E-07 16/80 R.IAQLEEELEEEQGNTELINDR[166.11].L sp|P35579|MYH9_HUMAN 1 2481.1746 1.07 54805 22006 3 2481.172063 828.0655 Myosin-9 OS=Homo sapiens OX=9606 GN=MYH9 PE=1 SV=4 3.72 3526.9 - 2.66E+06 - - - -1.0334 - 3.433 0.496 - 428.5 1 2 0 -0.0026 21 0 0 0 3.87E+07 3.62E+07 - - - 7.0263 1 221125_WJC_METTL3_EV_vs_WT_F04.22010.22010.2 7.49E-11 19/40 K.TIQNLYDLDEDDDGIASVPTK.Q "tr|Q8WUT1|Q8WUT1_HUMAN,tr|F8WEE2|F8WEE2_HUMAN" 2 2321.0911 1.64 54809 22010 2 2321.092132 1161.5528 POLDIP3 protein OS=Homo sapiens OX=9606 GN=POLDIP3 PE=1 SV=1 3.61 3527.2 - 2.39E+06 - - - 0.4588 - 4.011 0.686 - 625.9 1 2 0 0.0011 21 0 0 0 4.39E+07 2.67E+07 - - - 7.5225 0.9999 221125_WJC_METTL3_EV_vs_WT_F04.22011.22011.3 7.71E-05 15/44 K.IEEIK[136.11]DFLLTAR[166.11].R "sp|P63173|RL38_HUMAN,tr|J3KT73|J3KT73_HUMAN,tr|J3QL01|J3QL01_HUMAN,tr|J3KSP2|J3KSP2_HUMAN" 4 1464.8307 1.25 54810 22011 3 1464.831622 489.2842 60S ribosomal protein L38 OS=Homo sapiens OX=9606 GN=RPL38 PE=1 SV=2 4.68 3527.3 - 2.26E+06 - - - 0.6294 - 2.858 0.475 - 397.5 1 2 1 0.0009 12 0 0 0 2.89E+07 2.32E+07 - - - 6.7463 0.9998 221125_WJC_METTL3_EV_vs_WT_F04.22013.22013.3 0.00169 16/44 K.IEEIKDFLLTAR.R "sp|P63173|RL38_HUMAN,tr|J3KT73|J3KT73_HUMAN,tr|J3QL01|J3QL01_HUMAN,tr|J3KSP2|J3KSP2_HUMAN" 4 1446.8082 1.25 54812 22013 3 1446.805739 483.2767 60S ribosomal protein L38 OS=Homo sapiens OX=9606 GN=RPL38 PE=1 SV=2 4.68 3527.5 - 1.28E+06 - - - -1.7217 - 2.867 0.434 - 426.8 1 2 1 -0.0025 12 0 0 0 2.89E+07 2.32E+07 - - - 6.2975 1 221125_WJC_METTL3_EV_vs_WT_F04.22015.22015.2 5.86E-08 16/32 R.SAELPDAVGPIVQLQEK.L "sp|Q96PU8|QKI_HUMAN,tr|F5H5U6|F5H5U6_HUMAN,tr|F5GYM3|F5GYM3_HUMAN,tr|F5GXS8|F5GXS8_HUMAN,tr|F5GYT7|F5GYT7_HUMAN,tr|F5H8C8|F5H8C8_HUMAN,tr|H0YG47|H0YG47_HUMAN" 7 1792.9571 9.2 54814 22015 2 1792.96982 897.4858 Protein quaking OS=Homo sapiens OX=9606 GN=QKI PE=1 SV=1 4.14 3527.7 - 857406 - - - 7.1056 - 3.019 0.587 - 674.3 1 2 0 0.0127 17 0 0 0 1.51E+07 1.64E+06 - - - 6.0891 1 221125_WJC_METTL3_EV_vs_WT_F04.22020.22020.4 3.00E-08 23/126 K.AAAIGIDLGTTYSC[160.03]VGVFQHGK[136.11].V "sp|P0DMV8|HS71A_HUMAN,sp|P0DMV9|HS71B_HUMAN,tr|V9GZ37|V9GZ37_HUMAN,tr|A0A0G2JIW1|A0A0G2JIW1_HUMAN" 4 2272.1402 0.14 54817 22020 4 2272.144411 569.0423 Heat shock 70 kDa protein 1A OS=Homo sapiens OX=9606 GN=HSPA1A PE=1 SV=1 6.78 3528.3 - 2.55E+06 - - - 1.874 - 3.934 0.601 - 427.6 1 2 0 0.0043 22 0 0 0 3.19E+06 2.23E+07 - - - 4.9041 1 221125_WJC_METTL3_EV_vs_WT_F04.22026.22026.2 2.97E-06 20/42 K.AAAIGIDLGTTYSC[160.03]VGVFQHGK[136.11].V "sp|P0DMV8|HS71A_HUMAN,sp|P0DMV9|HS71B_HUMAN,tr|V9GZ37|V9GZ37_HUMAN,tr|A0A0G2JIW1|A0A0G2JIW1_HUMAN" 4 2272.1402 0.001 54823 22026 2 2272.13978 1137.0774 Heat shock 70 kDa protein 1A OS=Homo sapiens OX=9606 GN=HSPA1A PE=1 SV=1 6.78 3528.9 - 975531 - - - -0.1642 - 4.046 0.608 - 1238.8 1 2 0 -0.0004 22 0 0 0 0.00E+00 9.56E+06 - - - 6.968 1 221125_WJC_METTL3_EV_vs_WT_F04.22031.22031.3 9.16E-07 13/52 K.VDLK[136.11]PLLSSLSANK[136.11].E "sp|Q9NRA8|4ET_HUMAN,tr|B1AKL4|B1AKL4_HUMAN,tr|B0QYZ7|B0QYZ7_HUMAN" 3 1499.8894 1.26 54828 22031 3 1499.889852 500.9704 Eukaryotic translation initiation factor 4E transporter OS=Homo sapiens OX=9606 GN=EIF4ENIF1 PE=1 SV=2 8.56 3529.5 - 321710 - - - 0.3054 - 2.522 0.533 - 175.7 1 2 0 0.0005 14 0 0 0 7.24E+07 5.75E+07 - - - 6.9407 1 221125_WJC_METTL3_EV_vs_WT_F04.22033.22033.3 1.75E-08 20/80 R.IAQLEEELEEEQGNTELINDR.L sp|P35579|MYH9_HUMAN 1 2471.1664 1.07 54829 22033 3 2471.167103 824.7294 Myosin-9 OS=Homo sapiens OX=9606 GN=MYH9 PE=1 SV=4 3.72 3529.7 - 3.68E+06 - - - 0.3019 - 3.699 0.586 - 654.9 1 2 0 0.0007 21 0 0 0 3.87E+07 3.63E+07 - - - 8.2091 1 221125_WJC_METTL3_EV_vs_WT_F04.22039.22039.3 1.68E-06 Dec-68 K.EGGGGISC[160.03]VLQDGC[160.03]VFEK[136.11].A sp|P36551|HEM6_HUMAN 1 1918.8644 0.81 54834 22039 3 1918.862331 640.6288 "Oxygen-dependent coproporphyrinogen-III oxidase, mitochondrial OS=Homo sapiens OX=9606 GN=CPOX PE=1 SV=3" 4.14 3530.4 - 704337 - - - -1.1038 - 2.402 0.521 - 198.1 1 2 0 -0.0021 18 0 0 0 5.85E+06 7.21E+06 - - - 6.5301 1 221125_WJC_METTL3_EV_vs_WT_F04.22040.22040.3 3.11E-09 17/56 K.KAQDEGLLSDVVPFK.V "sp|P55084|ECHB_HUMAN,tr|F5GZQ3|F5GZQ3_HUMAN" 2 1644.8723 0.34 54835 22040 3 1644.872129 549.298 "Trifunctional enzyme subunit beta, mitochondrial OS=Homo sapiens OX=9606 GN=HADHB PE=1 SV=3" 4.56 3530.6 - 636000 - - - -0.0961 - 3.097 0.61 - 389.4 1 2 0 -0.0002 15 0 0 0 5.97E+06 1.76E+07 - - - 8.2906 1 221125_WJC_METTL3_EV_vs_WT_F04.22041.22041.3 3.41E-08 13/52 K.VDLKPLLSSLSANK.E "sp|Q9NRA8|4ET_HUMAN,tr|B1AKL4|B1AKL4_HUMAN,tr|B0QYZ7|B0QYZ7_HUMAN" 3 1483.861 1.26 54836 22041 3 1483.859123 495.6276 Eukaryotic translation initiation factor 4E transporter OS=Homo sapiens OX=9606 GN=EIF4ENIF1 PE=1 SV=2 8.56 3530.7 - 536116 - - - -1.2609 - 2.746 0.585 - 172.6 1 2 0 -0.0019 14 0 0 0 7.24E+07 5.75E+07 - - - 7.7461 1 221125_WJC_METTL3_EV_vs_WT_F04.22043.22043.3 2.01E-12 13/80 K.TIQNLYDLDEDDDGIASVPTK.Q "tr|Q8WUT1|Q8WUT1_HUMAN,tr|F8WEE2|F8WEE2_HUMAN" 2 2321.0911 1.73 54837 22043 3 2321.091826 774.7043 POLDIP3 protein OS=Homo sapiens OX=9606 GN=POLDIP3 PE=1 SV=1 3.61 3530.9 - 5.31E+06 - - - 0.327 - 3.015 0.543 - 122.7 1 2 0 0.0008 21 0 0 0 1.02E+08 5.88E+07 - - - 7.2395 1 221125_WJC_METTL3_EV_vs_WT_F04.22045.22045.3 2.23E-08 17/88 R.LVGQGASAVLLDLPNSGGEAQAK[136.11].K "sp|Q99714|HCD2_HUMAN,tr|Q5H928|Q5H928_HUMAN,tr|A0A804HHW5|A0A804HHW5_HUMAN" 3 2202.1736 0.8 54839 22045 3 2202.171964 735.0651 3-hydroxyacyl-CoA dehydrogenase type-2 OS=Homo sapiens OX=9606 GN=HSD17B10 PE=1 SV=3 4.37 3531.1 - 3.97E+06 - - - -0.7252 - 3.653 0.572 - 176.2 1 2 0 -0.0016 23 0 0 0 3.13E+07 3.92E+07 - - - 7.9561 1 221125_WJC_METTL3_EV_vs_WT_F04.22047.22047.2 7.83E-12 18/40 K.TIQNLYDLDEDDDGIASVPTK[136.11].Q "tr|Q8WUT1|Q8WUT1_HUMAN,tr|F8WEE2|F8WEE2_HUMAN" 2 2329.1053 1.64 54841 22047 2 2329.104457 1165.5599 POLDIP3 protein OS=Homo sapiens OX=9606 GN=POLDIP3 PE=1 SV=1 3.61 3531.3 - 1.01E+06 - - - -0.3478 - 3.702 0.713 - 586.3 1 2 0 -0.0008 21 0 0 0 4.39E+07 2.67E+07 - - - 7.5249 1 221125_WJC_METTL3_EV_vs_WT_F04.22048.22048.2 4.29E-12 19/34 K.EGGGGISC[160.03]VLQDGC[160.03]VFEK.A sp|P36551|HEM6_HUMAN 1 1910.8502 1.48 54842 22048 2 1910.848746 956.4324 "Oxygen-dependent coproporphyrinogen-III oxidase, mitochondrial OS=Homo sapiens OX=9606 GN=CPOX PE=1 SV=3" 4.14 3531.4 - 808787 - - - -0.7866 - 3.208 0.699 - 1114.1 1 2 0 -0.0015 18 0 0 0 9.48E+06 6.41E+06 - - - 7.0691 1 221125_WJC_METTL3_EV_vs_WT_F04.22051.22051.3 1.93E-08 Dec-60 K.TTQIPQYLFEEGYTNK.G "sp|O60231|DHX16_HUMAN,tr|A0A140T947|A0A140T947_HUMAN" 2 1930.9313 0.26 54845 22051 3 1930.930888 644.651 Pre-mRNA-splicing factor ATP-dependent RNA helicase DHX16 OS=Homo sapiens OX=9606 GN=DHX16 PE=1 SV=2 4.53 3531.8 - 430875 - - - -0.1921 - 2.788 0.58 - 140 1 2 0 -0.0004 16 0 0 0 1.83E+07 7.05E+07 - - - 7.6372 1 221125_WJC_METTL3_EV_vs_WT_F04.22055.22055.3 0.000416 17/56 K.K[136.11]IEDNNTLVFIVDVK[136.11].A "sp|P62750|RL23A_HUMAN,tr|K7EMA7|K7EMA7_HUMAN,tr|H7BY10|H7BY10_HUMAN,tr|K7ERT8|K7ERT8_HUMAN,tr|A8MUS3|A8MUS3_HUMAN,tr|K7EJV9|K7EJV9_HUMAN" 6 1761.9848 0.45 54847 22055 3 1761.986821 588.3355 60S ribosomal protein L23a OS=Homo sapiens OX=9606 GN=RPL23A PE=1 SV=1 4.56 3532.3 - 1.08E+06 - - - 1.1748 - 3.421 0.492 - 496.4 1 2 0 0.0021 15 0 0 0 8.82E+06 1.94E+07 - - - 7.2341 0.9998 221125_WJC_METTL3_EV_vs_WT_F04.22056.22056.4 8.28E-06 22/114 R.HVAEVLEYTK[136.11]DEQLESLFQR[166.11].T "sp|P05198|IF2A_HUMAN,tr|H0YJS4|H0YJS4_HUMAN,tr|G3V4T5|G3V4T5_HUMAN" 3 2451.2401 0.92 54848 22056 4 2451.245045 613.8173 Eukaryotic translation initiation factor 2 subunit 1 OS=Homo sapiens OX=9606 GN=EIF2S1 PE=1 SV=3 4.57 3532.5 - 1.02E+06 - - - 2.0275 - 3.455 0.518 - 211.5 1 2 1 0.005 20 0 0 0 1.51E+07 1.65E+07 - - - 4.1478 1 221125_WJC_METTL3_EV_vs_WT_F04.22057.22057.4 1.14E-12 23/114 R.HVAEVLEYTKDEQLESLFQR.T "sp|P05198|IF2A_HUMAN,tr|H0YJS4|H0YJS4_HUMAN,tr|G3V4T5|G3V4T5_HUMAN" 3 2433.2176 0.92 54849 22057 4 2433.224962 609.3117 Eukaryotic translation initiation factor 2 subunit 1 OS=Homo sapiens OX=9606 GN=EIF2S1 PE=1 SV=3 4.57 3532.6 - 896853 - - - 3.0236 - 3.854 0.641 - 455.3 1 2 1 0.0074 20 0 0 0 1.51E+07 1.65E+07 - - - 5.2543 1 221125_WJC_METTL3_EV_vs_WT_F04.22058.22058.2 1.82E-10 16/34 K.EGGGGISC[160.03]VLQDGC[160.03]VFEK[136.11].A sp|P36551|HEM6_HUMAN 1 1918.8644 1.48 54850 22058 2 1918.863276 960.4395 "Oxygen-dependent coproporphyrinogen-III oxidase, mitochondrial OS=Homo sapiens OX=9606 GN=CPOX PE=1 SV=3" 4.14 3532.7 - 817620 - - - -0.6113 - 3.002 0.669 - 695.6 1 2 0 -0.0012 18 0 0 0 9.48E+06 6.41E+06 - - - 6.6845 0.9998 221125_WJC_METTL3_EV_vs_WT_F04.22060.22060.3 0.000125 Sep-60 R.TDEGTEVAFPLLVSHR.S sp|Q7Z589|EMSY_HUMAN 1 1769.8948 0.24 54852 22060 3 1769.894124 590.9722 BRCA2-interacting transcriptional repressor EMSY OS=Homo sapiens OX=9606 GN=EMSY PE=1 SV=2 4.65 3533 - 326385 - - - -0.3899 - 1.844 0.41 - 72.5 1 2 0 -0.0007 16 0 0 0 6.07E+06 2.48E+07 - - - 4.6811 1 221125_WJC_METTL3_EV_vs_WT_F04.22063.22063.3 7.60E-09 20/92 K.IFTASNVSSVPLPAENVTITAGQR.L "sp|Q14157|UBP2L_HUMAN,tr|F8W726|F8W726_HUMAN,tr|Q5VU77|Q5VU77_HUMAN" 3 2471.302 2.48 54853 22063 3 2471.301058 824.7746 Ubiquitin-associated protein 2-like OS=Homo sapiens OX=9606 GN=UBAP2L PE=1 SV=2 6 3533.4 - 962970 - - - -0.3824 - 3.549 0.594 - 345 1 2 0 -0.0009 24 0 0 0 2.15E+08 8.68E+07 - - - 8.1042 0.9999 221125_WJC_METTL3_EV_vs_WT_F04.22064.22064.4 1.87E-10 18/96 K.LSDFDREHFSEVFVDLK.W sp|Q8IZH2|XRN1_HUMAN 1 2082.0058 1.23 54854 22064 4 2082.007353 521.5087 5'-3' exoribonuclease 1 OS=Homo sapiens OX=9606 GN=XRN1 PE=1 SV=1 4.43 3533.5 - 967997 - - - 0.7358 - 3.402 0.585 - 286.7 1 2 1 0.0015 17 0 0 0 1.44E+07 1.17E+07 - - - 4.7425 1 221125_WJC_METTL3_EV_vs_WT_F04.22065.22065.3 3.83E-15 28/76 R.HVAEVLEYTKDEQLESLFQR.T "sp|P05198|IF2A_HUMAN,tr|H0YJS4|H0YJS4_HUMAN,tr|G3V4T5|G3V4T5_HUMAN" 3 2433.2176 0.76 54855 22065 3 2433.222992 812.0798 Eukaryotic translation initiation factor 2 subunit 1 OS=Homo sapiens OX=9606 GN=EIF2S1 PE=1 SV=3 4.57 3533.6 - 1.05E+06 - - - 2.2139 - 5.133 0.709 - 914.8 1 2 1 0.0054 20 0 0 0 9.39E+06 1.24E+07 - - - 10.4114 0.9999 221125_WJC_METTL3_EV_vs_WT_F04.22066.22066.4 1.61E-09 16/96 K.LSDFDR[166.11]EHFSEVFVDLK[136.11].W sp|Q8IZH2|XRN1_HUMAN 1 2100.0283 1.23 54856 22066 4 2100.030757 526.0143 5'-3' exoribonuclease 1 OS=Homo sapiens OX=9606 GN=XRN1 PE=1 SV=1 4.43 3533.7 - 1.00E+06 - - - 1.1743 - 3.273 0.613 - 224 1 2 1 0.0025 17 0 0 0 1.46E+07 1.19E+07 - - - 4.9725 1 221125_WJC_METTL3_EV_vs_WT_F04.22067.22067.3 3.30E-10 28/76 R.HVAEVLEYTK[136.11]DEQLESLFQR[166.11].T "sp|P05198|IF2A_HUMAN,tr|H0YJS4|H0YJS4_HUMAN,tr|G3V4T5|G3V4T5_HUMAN" 3 2451.2401 0.74 54857 22067 3 2451.242232 818.0873 Eukaryotic translation initiation factor 2 subunit 1 OS=Homo sapiens OX=9606 GN=EIF2S1 PE=1 SV=3 4.57 3533.9 - 960580 - - - 0.88 - 5.016 0.675 - 810 1 2 1 0.0022 20 0 0 0 9.39E+06 1.27E+07 - - - 9.9773 1 221125_WJC_METTL3_EV_vs_WT_F04.22068.22068.3 8.81E-16 17/92 K.VIQNSTEC[160.03]TDAQQASLLPSVPALK.G tr|H7C0V5|H7C0V5_HUMAN 1 2569.3058 2.18 54858 22068 3 2569.306147 857.4425 ANKHD1-EIF4EBP3 readthrough (Fragment) OS=Homo sapiens OX=9606 GN=ANKHD1-EIF4EBP3 PE=4 SV=1 4.37 3534 - 795703 - - - 0.1475 - 3.216 0.722 - 200.3 1 2 0 0.0004 24 0 0 0 1.31E+07 6.02E+06 - - - 9.3026 1 221125_WJC_METTL3_EV_vs_WT_F04.22071.22071.2 7.70E-10 20/42 M.APPAPGPASGGSGEVDELFDVK.N "sp|O14579|COPE_HUMAN,tr|M0QXB4|M0QXB4_HUMAN,tr|M0R061|M0R061_HUMAN" 3 2096.0062 1.42 54861 22071 2 2096.013102 1049.0104 Coatomer subunit epsilon OS=Homo sapiens OX=9606 GN=COPE PE=1 SV=3 3.92 3534.4 - 444571 - - - 3.2858 - 3.883 0.733 - 864.3 1 2 0 0.0069 22 0 0 0 1.78E+07 1.25E+07 - - - 7.7881 0.9559 221125_WJC_METTL3_EV_vs_WT_F04.22072.22072.3 5.70E-05 Nov-64 R.SAELPDAVGPIVQLQEK.L "sp|Q96PU8|QKI_HUMAN,tr|F5H5U6|F5H5U6_HUMAN,tr|F5GYM3|F5GYM3_HUMAN,tr|F5GXS8|F5GXS8_HUMAN,tr|F5GYT7|F5GYT7_HUMAN,tr|F5H8C8|F5H8C8_HUMAN,tr|H0YG47|H0YG47_HUMAN" 7 1792.9571 16.44 54862 22072 3 1792.968299 598.6596 Protein quaking OS=Homo sapiens OX=9606 GN=QKI PE=1 SV=1 4.14 3534.5 - 387752 - - - 6.2573 - 2.318 0.226 - 184.8 1 2 0 0.0112 17 0 0 0 6.30E+06 3.83E+05 - - - 3.1804 1 221125_WJC_METTL3_EV_vs_WT_F04.22073.22073.2 1.40E-07 16/42 M.APPAPGPASGGSGEVDELFDVK[136.11].N "sp|O14579|COPE_HUMAN,tr|M0QXB4|M0QXB4_HUMAN,tr|M0R061|M0R061_HUMAN" 3 2104.0204 1.42 54863 22073 2 2104.026447 1053.0175 Coatomer subunit epsilon OS=Homo sapiens OX=9606 GN=COPE PE=1 SV=3 3.92 3534.7 - 335182 - - - 2.8669 - 3.316 0.663 - 591.9 1 2 0 0.006 22 0 0 0 1.78E+07 1.25E+07 - - - 6.8832 0.9992 221125_WJC_METTL3_EV_vs_WT_F04.22077.22077.3 3.44E-11 19/72 K.WSPTHEQQLISGSLDNIVK.L sp|Q9GZL7|WDR12_HUMAN 1 2151.096 0.6 54865 22077 3 2151.107365 718.0393 Ribosome biogenesis protein WDR12 OS=Homo sapiens OX=9606 GN=WDR12 PE=1 SV=2 5.32 3535.1 - 3.90E+06 - - - 5.268 - 3.389 0.412 - 410.4 1 2 0 0.0113 19 0 0 0 2.31E+07 3.84E+07 - - - 6.1289 1 221125_WJC_METTL3_EV_vs_WT_F04.22078.22078.3 3.18E-09 22/92 K.IFTASNVSSVPLPAENVTITAGQR[166.11].L "sp|Q14157|UBP2L_HUMAN,tr|F8W726|F8W726_HUMAN,tr|Q5VU77|Q5VU77_HUMAN" 3 2481.3103 2.48 54866 22078 3 2481.311389 828.1107 Ubiquitin-associated protein 2-like OS=Homo sapiens OX=9606 GN=UBAP2L PE=1 SV=2 6 3535.2 - 1.70E+06 - - - 0.4498 - 3.956 0.58 - 434.2 1 2 0 0.0011 24 0 0 0 2.15E+08 8.68E+07 - - - 8.2002 1 221125_WJC_METTL3_EV_vs_WT_F04.22080.22080.3 7.09E-13 35/116 F.MLQQSTNPAPGILGPPPPSFHLGGPAVGPR.G "sp|P43243|MATR3_HUMAN,tr|D6RE02|D6RE02_HUMAN,tr|B3KM87|B3KM87_HUMAN,tr|A8MXP9|A8MXP9_HUMAN,tr|D6RAY2|D6RAY2_HUMAN,tr|D6R991|D6R991_HUMAN,tr|A0A0R4J2E8|A0A0R4J2E8_HUMAN,tr|D6RAM9|D6RAM9_HUMAN,tr|D6RIA2|D6RIA2_HUMAN,tr|H0Y8T4|H0Y8T4_HUMAN,tr|D6REM6|D6REM6_HUMAN,tr|D6RBI2|D6RBI2_HUMAN" 12 2989.5596 1.97 54868 22080 3 2989.560452 997.5272 Matrin-3 OS=Homo sapiens OX=9606 GN=MATR3 PE=1 SV=2 9.52 3535.5 - 1.33E+06 - - - 0.2746 - 4.991 0.658 - 1119.1 1 1 0 0.0008 30 0 0 0 3.62E+07 1.84E+07 - - - 9.5744 1 221125_WJC_METTL3_EV_vs_WT_F04.22081.22081.4 1.70E-05 18/102 R.TDYHILNDPELSFLDAHK.N sp|Q9P2D1|CHD7_HUMAN 1 2127.0273 1.48 54869 22081 4 2127.029229 532.7641 Chromodomain-helicase-DNA-binding protein 7 OS=Homo sapiens OX=9606 GN=CHD7 PE=1 SV=3 4.63 3535.6 - 1.21E+06 - - - 0.9144 - 3.41 0.504 - 243.4 1 2 0 0.0019 18 0 0 0 7.48E+06 5.07E+06 - - - 4.0325 1 221125_WJC_METTL3_EV_vs_WT_F04.22082.22082.3 5.36E-13 25/64 K.LSDFDREHFSEVFVDLK.W sp|Q8IZH2|XRN1_HUMAN 1 2082.0058 0.85 54870 22082 3 2082.010936 695.0092 5'-3' exoribonuclease 1 OS=Homo sapiens OX=9606 GN=XRN1 PE=1 SV=1 4.43 3535.7 - 1.20E+06 - - - 2.4568 - 4.631 0.596 - 1007.3 1 2 1 0.0051 17 0 0 0 8.64E+06 1.02E+07 - - - 9.0556 1 221125_WJC_METTL3_EV_vs_WT_F04.22084.22084.4 1.52E-10 30/174 F.MLQQSTNPAPGILGPPPPSFHLGGPAVGPR.G "sp|P43243|MATR3_HUMAN,tr|D6RE02|D6RE02_HUMAN,tr|B3KM87|B3KM87_HUMAN,tr|A8MXP9|A8MXP9_HUMAN,tr|D6RAY2|D6RAY2_HUMAN,tr|D6R991|D6R991_HUMAN,tr|A0A0R4J2E8|A0A0R4J2E8_HUMAN,tr|D6RAM9|D6RAM9_HUMAN,tr|D6RIA2|D6RIA2_HUMAN,tr|H0Y8T4|H0Y8T4_HUMAN,tr|D6REM6|D6REM6_HUMAN,tr|D6RBI2|D6RBI2_HUMAN" 12 2989.5596 2.02 54872 22084 4 2989.569627 748.3972 Matrin-3 OS=Homo sapiens OX=9606 GN=MATR3 PE=1 SV=2 9.52 3535.9 - 830420 - - - 3.3436 - 5.346 0.647 - 431.4 1 1 0 0.01 30 0 0 0 1.35E+07 6.69E+06 - - - 5.3677 1 221125_WJC_METTL3_EV_vs_WT_F04.22090.22090.3 1.51E-15 24/84 M.APPAPGPASGGSGEVDELFDVK.N "sp|O14579|COPE_HUMAN,tr|M0QXB4|M0QXB4_HUMAN,tr|M0R061|M0R061_HUMAN" 3 2096.0062 1.25 54877 22090 3 2096.006998 699.676 Coatomer subunit epsilon OS=Homo sapiens OX=9606 GN=COPE PE=1 SV=3 3.92 3536.8 - 2.19E+06 - - - 0.3736 - 4.793 0.71 - 798.9 1 2 0 0.0008 22 0 0 0 4.27E+07 3.43E+07 - - - 10.1711 0.9999 221125_WJC_METTL3_EV_vs_WT_F04.22098.22098.3 1.47E-06 Nov-88 K.LEAPFTQDDTLGLENSHPVWTQK[136.11].E "sp|Q9Y6A5|TACC3_HUMAN,tr|A0A087WUE2|A0A087WUE2_HUMAN,tr|A0A494BZT8|A0A494BZT8_HUMAN,tr|C9JA91|C9JA91_HUMAN,tr|E7EMT0|E7EMT0_HUMAN" 5 2633.2853 1.34 54884 22098 3 2633.290582 878.769 Transforming acidic coiled-coil-containing protein 3 OS=Homo sapiens OX=9606 GN=TACC3 PE=1 SV=1 4.31 3537.7 - 658663 - - - 2.007 - 2.416 0.516 - 94.9 1 2 0 0.0053 23 0 0 0 5.94E+06 4.42E+06 - - - 6.3608 1 221125_WJC_METTL3_EV_vs_WT_F04.22102.22102.3 1.44E-12 35/116 F.MLQQSTNPAPGILGPPPPSFHLGGPAVGPR[166.11].G "sp|P43243|MATR3_HUMAN,tr|D6RE02|D6RE02_HUMAN,tr|B3KM87|B3KM87_HUMAN,tr|A8MXP9|A8MXP9_HUMAN,tr|D6RAY2|D6RAY2_HUMAN,tr|D6R991|D6R991_HUMAN,tr|A0A0R4J2E8|A0A0R4J2E8_HUMAN,tr|D6RAM9|D6RAM9_HUMAN,tr|D6RIA2|D6RIA2_HUMAN,tr|H0Y8T4|H0Y8T4_HUMAN,tr|D6REM6|D6REM6_HUMAN,tr|D6RBI2|D6RBI2_HUMAN" 12 2999.5679 1.97 54886 22102 3 2999.565621 1000.8632 Matrin-3 OS=Homo sapiens OX=9606 GN=MATR3 PE=1 SV=2 9.52 3538.2 - 1.51E+06 - - - -0.7601 - 5.473 0.648 - 1250.3 1 1 0 -0.0023 30 0 0 0 3.62E+07 1.84E+07 - - - 9.6746 1 221125_WJC_METTL3_EV_vs_WT_F04.22106.22106.3 3.31E-09 18/84 R.SPK[136.11]PLLTGLMWAQQGTTPGTPK[136.11].L "sp|Q13724|MOGS_HUMAN,tr|A0A3B3IS52|A0A3B3IS52_HUMAN,tr|B8ZZE2|B8ZZE2_HUMAN,tr|A0A3B3IRI7|A0A3B3IRI7_HUMAN,tr|A0A3B3ITU6|A0A3B3ITU6_HUMAN,tr|A0A3B3ITC1|A0A3B3ITC1_HUMAN" 6 2324.2533 0.23 54890 22106 3 2324.257841 775.7584 Mannosyl-oligosaccharide glucosidase OS=Homo sapiens OX=9606 GN=MOGS PE=1 SV=5 10 3538.7 - 920084 - - - 1.937 - 3.133 0.597 - 373.8 1 2 0 0.0045 22 0 0 0 2.51E+06 1.09E+07 - - - 7.9022 1 221125_WJC_METTL3_EV_vs_WT_F04.22107.22107.3 0.00925 19/76 R.AFVHWYVGEGMEEGEFSEAR[166.11].E "sp|Q9NY65|TBA8_HUMAN,sp|Q6PEY2|TBA3E_HUMAN,sp|P0DPH7|TBA3C_HUMAN,sp|Q71U36|TBA1A_HUMAN,sp|P0DPH8|TBA3D_HUMAN,sp|P68366|TBA4A_HUMAN,sp|P68363|TBA1B_HUMAN,sp|Q9BQE3|TBA1C_HUMAN,tr|F5H5D3|F5H5D3_HUMAN,tr|C9J2C0|C9J2C0_HUMAN" 10 2339.0193 0.54 54891 22107 3 2339.020564 780.6804 Tubulin alpha-8 chain OS=Homo sapiens OX=9606 GN=TUBA8 PE=1 SV=1 4.32 3538.8 - 772517 - - - 0.5605 - 3.769 0.604 - 410.4 1 2 0 0.0013 20 0 0 0 1.85E+06 3.44E+06 - - - 8.4925 0.9872 221125_WJC_METTL3_EV_vs_WT_F04.22116.22116.3 0.22 15/60 R.DGLK[136.11]LMLLLEVISGER[166.11].L "sp|O43707|ACTN4_HUMAN,sp|P12814|ACTN1_HUMAN,tr|A0A804HK61|A0A804HK61_HUMAN,tr|A0A804HIN7|A0A804HIN7_HUMAN,tr|G3V5M4|G3V5M4_HUMAN,tr|A0A804HLF4|A0A804HLF4_HUMAN,tr|A0A804HIY0|A0A804HIY0_HUMAN,tr|A0A7I2V4Y4|A0A7I2V4Y4_HUMAN,tr|A0A804HII9|A0A804HII9_HUMAN,tr|A0A804HJQ9|A0A804HJQ9_HUMAN,tr|F5GXS2|F5GXS2_HUMAN,tr|A0A804HKE2|A0A804HKE2_HUMAN,tr|G3V2N5|G3V2N5_HUMAN,tr|A0A804HLD0|A0A804HLD0_HUMAN,tr|H7C144|H7C144_HUMAN" 15 1803.0295 0.99 54898 22116 3 1803.032135 602.0171 Alpha-actinin-4 OS=Homo sapiens OX=9606 GN=ACTN4 PE=1 SV=2 4.68 3540 - 930518 - - - 1.4742 - 2.094 0.215 - 239.4 1 2 1 0.0027 16 0 0 0 2.67E+06 2.69E+06 - - - 2.8327 1 221125_WJC_METTL3_EV_vs_WT_F04.22117.22117.4 5.54E-05 19/90 R.DYLHLPPEIVPATLR[166.11]R[166.11].S "sp|P46783|RS10_HUMAN,tr|A0A2R8Y6L3|A0A2R8Y6L3_HUMAN,tr|F6U211|F6U211_HUMAN,tr|A0A1W2PQS6|A0A1W2PQS6_HUMAN,tr|A0A2R8YFH6|A0A2R8YFH6_HUMAN,tr|A0A2R8Y7H1|A0A2R8Y7H1_HUMAN,tr|S4R435|S4R435_HUMAN" 7 1909.0689 1.09 54899 22117 4 1909.072128 478.2745 40S ribosomal protein S10 OS=Homo sapiens OX=9606 GN=RPS10 PE=1 SV=1 6.75 3540.1 - 566798 - - - 1.7134 - 3.193 0.547 - 278.1 1 2 0 0.0033 16 0 0 0 1.37E+07 1.25E+07 - - - 4.3951 1 221125_WJC_METTL3_EV_vs_WT_F04.22118.22118.2 4.15E-10 18/38 K.GHLDAELDAYMAQTDPETND.- "sp|Q9Y3Y2|CHTOP_HUMAN,tr|X6R700|X6R700_HUMAN" 2 2204.9168 - 54900 22118 2 2204.918349 1103.4657 Chromatin target of PRMT1 protein OS=Homo sapiens OX=9606 GN=CHTOP PE=1 SV=2 3.81 3540.2 - 535034 - - - 0.6993 - 3.263 0.754 - 866.7 1 2 0 0.0015 20 0 0 0 - - - - - 7.5172 1 221125_WJC_METTL3_EV_vs_WT_F04.22119.22119.3 1.96E-09 18/100 K.FAAEHTIFASNTSSLQITSIANATTR.Q "sp|Q16836|HCDH_HUMAN,tr|A0A1W2PQC2|A0A1W2PQC2_HUMAN,tr|A0A804HJW7|A0A804HJW7_HUMAN,tr|A0A0D9SFP2|A0A0D9SFP2_HUMAN,tr|E9PF18|E9PF18_HUMAN,tr|A0A0A0MSE2|A0A0A0MSE2_HUMAN,tr|A0A804HKJ2|A0A804HKJ2_HUMAN,tr|A0A1W2PRT2|A0A1W2PRT2_HUMAN,tr|A0A1W2PQV5|A0A1W2PQV5_HUMAN,tr|A0A1W2PNM1|A0A1W2PNM1_HUMAN" 10 2751.3828 1.38 54901 22119 3 2751.381988 918.1349 "Hydroxyacyl-coenzyme A dehydrogenase, mitochondrial OS=Homo sapiens OX=9606 GN=HADH PE=1 SV=3" 6.75 3540.4 - 486376 - - - -0.2849 - 3.107 0.604 - 220 1 2 0 -0.0008 26 0 0 0 4.77E+06 3.45E+06 - - - 7.8819 1 221125_WJC_METTL3_EV_vs_WT_F04.22120.22120.3 2.55E-09 15/56 K.RGIEKPPFELPDFIK.R "sp|Q13435|SF3B2_HUMAN,tr|E9PPJ0|E9PPJ0_HUMAN" 2 1784.9825 0.8 54902 22120 3 1784.98764 596.0014 Splicing factor 3B subunit 2 OS=Homo sapiens OX=9606 GN=SF3B2 PE=1 SV=2 6.18 3540.5 - 481537 - - - 2.8762 - 3.228 0.545 - 300.8 1 2 0 0.0051 15 0 0 0 3.41E+06 4.26E+06 - - - 7.6726 1 221125_WJC_METTL3_EV_vs_WT_F04.22121.22121.2 5.08E-09 18/46 K.IFTASNVSSVPLPAENVTITAGQR.L "sp|Q14157|UBP2L_HUMAN,tr|F8W726|F8W726_HUMAN,tr|Q5VU77|Q5VU77_HUMAN" 3 2471.302 4.19 54903 22121 2 2471.308169 1236.6583 Ubiquitin-associated protein 2-like OS=Homo sapiens OX=9606 GN=UBAP2L PE=1 SV=2 6 3540.6 - 475187 - - - 2.495 - 3.693 0.655 - 346 1 2 0 0.0062 24 0 0 0 5.65E+06 1.35E+06 - - - 7.0888 1 221125_WJC_METTL3_EV_vs_WT_F04.22122.22122.3 4.12E-09 15/56 K.R[166.11]GIEK[136.11]PPFELPDFIK[136.11].R "sp|Q13435|SF3B2_HUMAN,tr|E9PPJ0|E9PPJ0_HUMAN" 2 1811.0192 2.88 54904 22122 3 1811.017899 604.6803 Splicing factor 3B subunit 2 OS=Homo sapiens OX=9606 GN=SF3B2 PE=1 SV=2 6.18 3540.8 - 418960 - - - -0.7051 - 3.191 0.573 - 302.7 1 2 0 -0.0013 15 0 0 0 1.48E+07 5.16E+06 - - - 7.9558 0.9997 221125_WJC_METTL3_EV_vs_WT_F04.22124.22124.3 5.78E-05 Oct-60 R.DKGSAALGGVLALAER.S sp|Q6P582|MZT2A_HUMAN 1 1526.8417 3.85 54906 22124 3 1526.842298 509.9545 Mitotic-spindle organizing protein 2A OS=Homo sapiens OX=9606 GN=MZT2A PE=1 SV=2 6.07 3541 - 155675 - - - 0.4205 - 2.269 0.456 - 135.3 1 2 1 0.0006 16 0 0 0 1.46E+06 3.79E+05 - - - 5.7261 0.9999 221125_WJC_METTL3_EV_vs_WT_F04.22129.22129.4 1.68E-06 17/138 K.IFTASNVSSVPLPAENVTITAGQR.L "sp|Q14157|UBP2L_HUMAN,tr|F8W726|F8W726_HUMAN,tr|Q5VU77|Q5VU77_HUMAN" 3 2471.302 1 54909 22129 4 2471.30311 618.8328 Ubiquitin-associated protein 2-like OS=Homo sapiens OX=9606 GN=UBAP2L PE=1 SV=2 6 3541.7 - 868674 - - - 0.4479 - 2.803 0.437 - 131.6 1 2 0 0.0011 24 0 0 0 4.53E+06 4.55E+06 - - - 3.3602 0.9936 221125_WJC_METTL3_EV_vs_WT_F04.22130.22130.3 3.96E-06 14/100 R.TTGIVMDSGDGVTHTVPIYEGYALPH.A "sp|P63261|ACTG_HUMAN,sp|P60709|ACTB_HUMAN,tr|A0A804GS07|A0A804GS07_HUMAN,tr|I3L3I0|I3L3I0_HUMAN,tr|E7EVS6|E7EVS6_HUMAN,tr|A0A6Q8PFE4|A0A6Q8PFE4_HUMAN,tr|I3L1U9|I3L1U9_HUMAN,tr|A0A2R8YEA7|A0A2R8YEA7_HUMAN,tr|A0A2R8Y793|A0A2R8Y793_HUMAN,tr|I3L4N8|I3L4N8_HUMAN" 10 2729.3007 - 54910 22130 3 2729.299121 910.7742 "Actin, cytoplasmic 2 OS=Homo sapiens OX=9606 GN=ACTG1 PE=1 SV=1" 4.51 3541.8 - 2.39E+06 - - - -0.5719 - 2.448 0.456 - 100.7 1 1 0 -0.0016 26 0 0 0 - - - - - 5.6832 0.9935 221125_WJC_METTL3_EV_vs_WT_F04.22132.22132.2 0.0119 30-Dec R.DGLK[136.11]LMLLLEVISGER[166.11].L "sp|O43707|ACTN4_HUMAN,sp|P12814|ACTN1_HUMAN,tr|A0A804HK61|A0A804HK61_HUMAN,tr|A0A804HIN7|A0A804HIN7_HUMAN,tr|G3V5M4|G3V5M4_HUMAN,tr|A0A804HLF4|A0A804HLF4_HUMAN,tr|A0A804HIY0|A0A804HIY0_HUMAN,tr|A0A7I2V4Y4|A0A7I2V4Y4_HUMAN,tr|A0A804HII9|A0A804HII9_HUMAN,tr|A0A804HJQ9|A0A804HJQ9_HUMAN,tr|F5GXS2|F5GXS2_HUMAN,tr|A0A804HKE2|A0A804HKE2_HUMAN,tr|G3V2N5|G3V2N5_HUMAN,tr|A0A804HLD0|A0A804HLD0_HUMAN,tr|H7C144|H7C144_HUMAN" 15 1803.0295 0.001 54912 22132 2 1803.031781 902.522 Alpha-actinin-4 OS=Homo sapiens OX=9606 GN=ACTN4 PE=1 SV=2 4.68 3542.1 - 726418 - - - 1.2778 - 2.066 0.334 - 385.9 1 2 1 0.0023 16 0 0 0 0.00E+00 5.25E+09 - - - 3.2912 1 221125_WJC_METTL3_EV_vs_WT_F04.22133.22133.4 3.68E-08 18/90 R.DYLHLPPEIVPATLRR.S "sp|P46783|RS10_HUMAN,tr|A0A2R8Y6L3|A0A2R8Y6L3_HUMAN,tr|F6U211|F6U211_HUMAN,tr|A0A1W2PQS6|A0A1W2PQS6_HUMAN,tr|A0A2R8YFH6|A0A2R8YFH6_HUMAN,tr|A0A2R8Y7H1|A0A2R8Y7H1_HUMAN,tr|S4R435|S4R435_HUMAN" 7 1889.0523 1.05 54913 22133 4 1889.053578 473.2704 40S ribosomal protein S10 OS=Homo sapiens OX=9606 GN=RPS10 PE=1 SV=1 6.75 3542.2 - 697959 - - - 0.6675 - 3.047 0.531 - 234.8 1 2 0 0.0013 16 0 0 0 1.26E+07 1.20E+07 - - - 4.2399 0.9999 221125_WJC_METTL3_EV_vs_WT_F04.22135.22135.3 8.76E-08 20/76 K.SSATSGDIWPGLSAYDNSPR.S "sp|Q9NYF8|BCLF1_HUMAN,tr|E9PKI6|E9PKI6_HUMAN,tr|A0A1W2PQ43|A0A1W2PQ43_HUMAN,tr|E9PK91|E9PK91_HUMAN,tr|E9PJA7|E9PJA7_HUMAN,tr|E9PK09|E9PK09_HUMAN,tr|E9PQN2|E9PQN2_HUMAN" 7 2079.9498 3.44 54915 22135 3 2079.956868 694.3239 Bcl-2-associated transcription factor 1 OS=Homo sapiens OX=9606 GN=BCLAF1 PE=1 SV=2 4.21 3542.4 - 574873 - - - 3.4164 - 3.205 0.563 - 489.4 1 2 0 0.0071 20 0 0 0 1.38E+08 4.02E+07 - - - 7.6405 0.9999 221125_WJC_METTL3_EV_vs_WT_F04.22143.22143.4 2.96E-15 29/126 K.VAEKLDEIYVAGLVAHSDLDER.A "sp|O60506|HNRPQ_HUMAN,tr|A0A7I2YQV8|A0A7I2YQV8_HUMAN,tr|A0A7I2YQN2|A0A7I2YQN2_HUMAN,tr|A0A7I2V5Q6|A0A7I2V5Q6_HUMAN,tr|A0A7I2V4Z0|A0A7I2V4Z0_HUMAN,tr|A0A7I2V4J0|A0A7I2V4J0_HUMAN,tr|F6UXX1|F6UXX1_HUMAN,tr|A0A7I2V346|A0A7I2V346_HUMAN" 8 2441.2438 1.32 54921 22143 4 2441.245773 611.3182 Heterogeneous nuclear ribonucleoprotein Q OS=Homo sapiens OX=9606 GN=SYNCRIP PE=1 SV=2 4.29 3543.5 - 946248 - - - 0.8004 - 4.803 0.543 - 699.5 1 2 1 0.002 22 0 0 0 8.56E+07 6.48E+07 - - - 4.4652 0.9688 221125_WJC_METTL3_EV_vs_WT_F04.22144.22144.3 0.0839 Oct-92 R.VAPPYPHLFSSC[160.03]SPPGMVLDGSPK.G "sp|Q9BUK6|MSTO1_HUMAN,tr|V9GYF2|V9GYF2_HUMAN" 2 2539.224 2.68 54922 22144 3 2539.225283 847.4153 Protein misato homolog 1 OS=Homo sapiens OX=9606 GN=MSTO1 PE=1 SV=1 6.7 3543.6 - 916024 - - - 0.5238 - 1.8 0.11 - 73.3 1 2 0 0.0013 24 0 0 0 1.04E+07 3.89E+06 - - - 1.1312 1 221125_WJC_METTL3_EV_vs_WT_F04.22145.22145.3 1.14E-05 17/84 K.LLQLPSTTIENISVSVHQPQPK.H sp|Q5T6F2|UBAP2_HUMAN 1 2428.3326 0.75 54923 22145 3 2428.331919 810.4515 Ubiquitin-associated protein 2 OS=Homo sapiens OX=9606 GN=UBAP2 PE=1 SV=1 6.75 3543.7 - 850697 - - - -0.2701 - 2.951 0.506 - 266.4 1 2 0 -0.0007 22 0 0 0 6.73E+06 8.93E+06 - - - 6.7468 0.9999 221125_WJC_METTL3_EV_vs_WT_F04.22146.22146.3 2.69E-07 19/68 R.TVVSGLVQFVPKEELQDR.L "sp|P54577|SYYC_HUMAN,tr|A0A6Q8PFX2|A0A6Q8PFX2_HUMAN" 2 2043.1001 0.54 54924 22146 3 2043.100979 682.0406 "Tyrosine--tRNA ligase, cytoplasmic OS=Homo sapiens OX=9606 GN=YARS1 PE=1 SV=4" 4.68 3543.8 - 649024 - - - 0.4518 - 3.41 0.517 - 262 1 2 1 0.0009 18 0 0 0 3.13E+07 5.84E+07 - - - 7.3584 1 221125_WJC_METTL3_EV_vs_WT_F04.22151.22151.4 9.96E-13 26/126 K.VAEK[136.11]LDEIYVAGLVAHSDLDER[166.11].A "sp|O60506|HNRPQ_HUMAN,tr|A0A7I2YQV8|A0A7I2YQV8_HUMAN,tr|A0A7I2YQN2|A0A7I2YQN2_HUMAN,tr|A0A7I2V5Q6|A0A7I2V5Q6_HUMAN,tr|A0A7I2V4Z0|A0A7I2V4Z0_HUMAN,tr|A0A7I2V4J0|A0A7I2V4J0_HUMAN,tr|F6UXX1|F6UXX1_HUMAN,tr|A0A7I2V346|A0A7I2V346_HUMAN" 8 2459.2663 1.32 54927 22151 4 2459.261432 615.8238 Heterogeneous nuclear ribonucleoprotein Q OS=Homo sapiens OX=9606 GN=SYNCRIP PE=1 SV=2 4.29 3544.4 - 3.12E+06 - - - -1.975 - 5.058 0.651 - 531.4 1 2 1 -0.0049 22 0 0 0 8.56E+07 6.48E+07 - - - 5.4213 1 221125_WJC_METTL3_EV_vs_WT_F04.22152.22152.3 3.09E-13 27/92 R.TDDEVVQR[166.11]EEEAIQLDGLNASQIR[166.11].E "sp|P14625|ENPL_HUMAN,tr|A0A7P0Z405|A0A7P0Z405_HUMAN,tr|A0A7P0T823|A0A7P0T823_HUMAN,tr|A0A7P0TAE1|A0A7P0TAE1_HUMAN,tr|H0YIV0|H0YIV0_HUMAN,tr|A0A7P0T8R3|A0A7P0T8R3_HUMAN,tr|A0A7P0T885|A0A7P0T885_HUMAN,tr|A0A7P0TAY2|A0A7P0TAY2_HUMAN,tr|A0A087WT78|A0A087WT78_HUMAN,tr|A0A7P0TBC2|A0A7P0TBC2_HUMAN,tr|A0A7P0TAT8|A0A7P0TAT8_HUMAN" 11 2747.3477 0.77 54928 22152 3 2747.343629 916.7898 Endoplasmin OS=Homo sapiens OX=9606 GN=HSP90B1 PE=1 SV=1 3.95 3544.5 - 2.12E+06 - - - -1.4712 - 4.535 0.665 - 852.3 1 2 1 -0.004 24 0 0 0 1.23E+07 1.60E+07 - - - 9.4643 0.9917 221125_WJC_METTL3_EV_vs_WT_F04.22155.22155.2 0.0366 30-Nov R.DGLKLMLLLEVISGER[166.11].L "sp|O43707|ACTN4_HUMAN,sp|P12814|ACTN1_HUMAN,tr|A0A804HK61|A0A804HK61_HUMAN,tr|A0A804HIN7|A0A804HIN7_HUMAN,tr|G3V5M4|G3V5M4_HUMAN,tr|A0A804HLF4|A0A804HLF4_HUMAN,tr|A0A804HIY0|A0A804HIY0_HUMAN,tr|A0A7I2V4Y4|A0A7I2V4Y4_HUMAN,tr|A0A804HII9|A0A804HII9_HUMAN,tr|A0A804HJQ9|A0A804HJQ9_HUMAN,tr|F5GXS2|F5GXS2_HUMAN,tr|A0A804HKE2|A0A804HKE2_HUMAN,tr|G3V2N5|G3V2N5_HUMAN,tr|A0A804HLD0|A0A804HLD0_HUMAN,tr|H7C144|H7C144_HUMAN" 15 1795.0153 - 54931 22155 2 1795.013516 898.5149 Alpha-actinin-4 OS=Homo sapiens OX=9606 GN=ACTN4 PE=1 SV=2 4.68 3544.9 - 839154 - - - -0.9811 - 2.063 0.268 - 292.7 1 2 1 -0.0018 16 0 0 0 - - - - - 2.8003 1 221125_WJC_METTL3_EV_vs_WT_F04.22157.22157.3 1.84E-10 16/64 R.FGEDVVEVIK[136.11]DSNPVDK[136.11].C "sp|Q96N67|DOCK7_HUMAN,tr|A0A1B0GWE0|A0A1B0GWE0_HUMAN" 2 1904.9702 0.52 54933 22157 3 1904.961769 635.9974 Dedicator of cytokinesis protein 7 OS=Homo sapiens OX=9606 GN=DOCK7 PE=1 SV=4 4.11 3545.2 - 476021 - - - -4.4384 - 3.84 0.607 - 429.3 1 2 1 -0.0085 17 0 0 0 2.98E+06 5.76E+06 - - - 8.7042 1 221125_WJC_METTL3_EV_vs_WT_F04.22173.22173.3 2.64E-13 35/84 K.VAEKLDEIYVAGLVAHSDLDER.A "sp|O60506|HNRPQ_HUMAN,tr|A0A7I2YQV8|A0A7I2YQV8_HUMAN,tr|A0A7I2YQN2|A0A7I2YQN2_HUMAN,tr|A0A7I2V5Q6|A0A7I2V5Q6_HUMAN,tr|A0A7I2V4Z0|A0A7I2V4Z0_HUMAN,tr|A0A7I2V4J0|A0A7I2V4J0_HUMAN,tr|F6UXX1|F6UXX1_HUMAN,tr|A0A7I2V346|A0A7I2V346_HUMAN" 8 2441.2438 7.36 54943 22173 3 2441.247414 814.7552 Heterogeneous nuclear ribonucleoprotein Q OS=Homo sapiens OX=9606 GN=SYNCRIP PE=1 SV=2 4.29 3546.9 - 1.83E+06 - - - 1.4726 - 5.949 0.699 - 1597.9 1 2 1 0.0036 22 0 0 0 1.48E+07 2.01E+06 - - - 10.5599 0.9968 221125_WJC_METTL3_EV_vs_WT_F04.22176.22176.3 5.02E-05 18/68 R.TVVSGLVQFVPK[136.11]EELQDR[166.11].L "sp|P54577|SYYC_HUMAN,tr|A0A6Q8PFX2|A0A6Q8PFX2_HUMAN" 2 2061.1225 0.54 54944 22176 3 2061.112378 688.0481 "Tyrosine--tRNA ligase, cytoplasmic OS=Homo sapiens OX=9606 GN=YARS1 PE=1 SV=4" 4.68 3547.3 - 4.11E+06 - - - -4.9235 - 2.768 0.442 - 234.3 1 2 1 -0.0101 18 0 0 0 3.13E+07 5.84E+07 - - - 6.0003 1 221125_WJC_METTL3_EV_vs_WT_F04.22192.22192.3 1.74E-16 21/88 K.AFSAVDTDGNGTINAQELGAALK.A sp|Q9NZT1|CALL5_HUMAN 1 2262.1128 40.27 54951 22192 3 2262.100987 755.0449 Calmodulin-like protein 5 OS=Homo sapiens OX=9606 GN=CALML5 PE=1 SV=2 4.03 3549.2 - 6.86E+06 - - - -5.2243 - 3.366 0.73 - 481.6 1 2 0 -0.0118 23 0 0 0 4.27E+08 1.06E+07 - - - 9.5228 1 221125_WJC_METTL3_EV_vs_WT_F04.22196.22196.2 6.43E-10 19/32 R.DQSAVVVQGLPEGVAFK[136.11].H "sp|P78347|GTF2I_HUMAN,tr|A0A494C1K3|A0A494C1K3_HUMAN" 2 1750.9345 1.79 54954 22196 2 1750.92328 876.4745 General transcription factor II-I OS=Homo sapiens OX=9606 GN=GTF2I PE=1 SV=2 4.37 3549.6 - 2.94E+06 - - - -6.408 - 3.435 0.647 - 1048.6 1 2 0 -0.0112 17 0 0 0 2.93E+08 1.64E+08 - - - 6.8501 1 221125_WJC_METTL3_EV_vs_WT_F04.22199.22199.2 4.69E-11 18/32 R.DQSAVVVQGLPEGVAFK.H "sp|P78347|GTF2I_HUMAN,tr|A0A494C1K3|A0A494C1K3_HUMAN" 2 1742.9203 1.79 54955 22199 2 1742.913098 872.4674 General transcription factor II-I OS=Homo sapiens OX=9606 GN=GTF2I PE=1 SV=2 4.37 3550 - 5.30E+06 - - - -4.1321 - 3.242 0.664 - 982.9 1 2 0 -0.0072 17 0 0 0 2.93E+08 1.64E+08 - - - 6.8348 1 221125_WJC_METTL3_EV_vs_WT_F04.22201.22201.3 2.31E-10 21/88 K.LTETVVTEYLNSGNANEAVNGVR[166.11].E "sp|P78344|IF4G2_HUMAN,tr|E9PKF8|E9PKF8_HUMAN,tr|H0Y3P2|H0Y3P2_HUMAN,tr|D3DQV9|D3DQV9_HUMAN" 4 2459.2168 2.82 54957 22201 3 2459.20964 820.7462 Eukaryotic translation initiation factor 4 gamma 2 OS=Homo sapiens OX=9606 GN=EIF4G2 PE=1 SV=1 4.25 3550.1 - 1.04E+07 - - - -2.8977 - 3.777 0.618 - 448.8 1 2 0 -0.0071 23 0 0 0 5.80E+08 2.05E+08 - - - 8.5457 1 221125_WJC_METTL3_EV_vs_WT_F04.22206.22206.2 1.95E-17 23/44 K.AFSAVDTDGNGTINAQELGAALK.A sp|Q9NZT1|CALL5_HUMAN 1 2262.1128 999 54959 22206 2 2262.103171 1132.0637 Calmodulin-like protein 5 OS=Homo sapiens OX=9606 GN=CALML5 PE=1 SV=2 4.03 3550.7 - 3.27E+06 - - - -4.2589 - 4.338 0.77 - 1484.7 1 2 0 -0.0096 23 0 0 0 1.30E+08 0.00E+00 - - - 8.3329 1 221125_WJC_METTL3_EV_vs_WT_F04.22208.22208.2 4.14E-16 22/44 K.LTETVVTEYLNSGNANEAVNGVR.E "sp|P78344|IF4G2_HUMAN,tr|E9PKF8|E9PKF8_HUMAN,tr|H0Y3P2|H0Y3P2_HUMAN,tr|D3DQV9|D3DQV9_HUMAN" 4 2449.2085 4.38 54961 22208 2 2449.202963 1225.6115 Eukaryotic translation initiation factor 4 gamma 2 OS=Homo sapiens OX=9606 GN=EIF4G2 PE=1 SV=1 4.25 3551 - 3.43E+06 - - - -2.2591 - 5.021 0.711 - 1223.2 1 2 0 -0.0055 23 0 0 0 5.52E+07 1.26E+07 - - - 8.2579 1 221125_WJC_METTL3_EV_vs_WT_F04.22209.22209.3 6.54E-08 19/64 R.DQSAVVVQGLPEGVAFK[136.11].H "sp|P78347|GTF2I_HUMAN,tr|A0A494C1K3|A0A494C1K3_HUMAN" 2 1750.9345 1.4 54962 22209 3 1750.933684 584.6521 General transcription factor II-I OS=Homo sapiens OX=9606 GN=GTF2I PE=1 SV=2 4.37 3551.1 - 1.45E+06 - - - -0.466 - 3.493 0.508 - 387.3 1 2 0 -0.0008 17 0 0 0 8.15E+07 5.83E+07 - - - 7.3633 1 221125_WJC_METTL3_EV_vs_WT_F04.22212.22212.2 3.98E-09 17/30 K.SYELPDGQVITIGNER.F "sp|Q6S8J3|POTEE_HUMAN,sp|P63261|ACTG_HUMAN,sp|P68133|ACTS_HUMAN,sp|P62736|ACTA_HUMAN,sp|Q9BYX7|ACTBM_HUMAN,sp|P68032|ACTC_HUMAN,sp|Q562R1|ACTBL_HUMAN,sp|P60709|ACTB_HUMAN,sp|P63267|ACTH_HUMAN,sp|A5A3E0|POTEF_HUMAN,tr|A0A804GS07|A0A804GS07_HUMAN,tr|E7EVS6|E7EVS6_HUMAN,tr|A0A6Q8PFE4|A0A6Q8PFE4_HUMAN,tr|A0A2R8YEA7|A0A2R8YEA7_HUMAN,tr|A0A804HKV3|A0A804HKV3_HUMAN,tr|A0A2R8Y793|A0A2R8Y793_HUMAN,tr|I3L4N8|I3L4N8_HUMAN,tr|A6NL76|A6NL76_HUMAN" 18 1789.8846 1.07 54963 22212 2 1789.884025 895.9496 POTE ankyrin domain family member E OS=Homo sapiens OX=9606 GN=POTEE PE=2 SV=3 4.14 3551.5 - 4.84E+06 - - - -0.3453 - 3.037 0.688 - 836.8 1 2 0 -0.0006 16 0 0 0 2.36E+09 2.20E+09 - - - 6.8535 1 221125_WJC_METTL3_EV_vs_WT_F04.22219.22219.3 5.83E-09 17/64 R.DQSAVVVQGLPEGVAFK.H "sp|P78347|GTF2I_HUMAN,tr|A0A494C1K3|A0A494C1K3_HUMAN" 2 1742.9203 1.4 54969 22219 3 1742.919547 581.9807 General transcription factor II-I OS=Homo sapiens OX=9606 GN=GTF2I PE=1 SV=2 4.37 3552.1 - 3.17E+06 - - - -0.432 - 3.604 0.564 - 297 1 2 0 -0.0008 17 0 0 0 8.15E+07 5.83E+07 - - - 8.0667 1 221125_WJC_METTL3_EV_vs_WT_F04.22220.22220.2 2.10E-09 20/38 K.SSATSGDIWPGLSAYDNSPR.S "sp|Q9NYF8|BCLF1_HUMAN,tr|E9PKI6|E9PKI6_HUMAN,tr|A0A1W2PQ43|A0A1W2PQ43_HUMAN,tr|E9PK91|E9PK91_HUMAN,tr|E9PJA7|E9PJA7_HUMAN,tr|E9PK09|E9PK09_HUMAN,tr|E9PQN2|E9PQN2_HUMAN" 7 2079.9498 7.72 54970 22220 2 2079.947454 1040.9822 Bcl-2-associated transcription factor 1 OS=Homo sapiens OX=9606 GN=BCLAF1 PE=1 SV=2 4.21 3552.2 - 1.88E+06 - - - -1.1096 - 3.77 0.711 - 529.5 1 2 0 -0.0023 20 0 0 0 5.67E+07 7.35E+06 - - - 7.5544 0.9996 221125_WJC_METTL3_EV_vs_WT_F04.22225.22225.3 9.50E-06 16/52 R.EYFSWEGAFQHVGK[136.11].A sp|P26641|EF1G_HUMAN 1 1691.7824 1.49 54973 22225 3 1691.776338 564.9347 Elongation factor 1-gamma OS=Homo sapiens OX=9606 GN=EEF1G PE=1 SV=3 5.4 3552.8 - 2.16E+06 - - - -3.5578 - 2.046 0.46 - 189.4 1 2 0 -0.006 14 0 0 0 7.09E+07 4.75E+07 - - - 5.5694 0.9999 221125_WJC_METTL3_EV_vs_WT_F04.22229.22229.4 5.61E-09 17/114 R.GFAFVTFDDHDSVDK[136.11]IVIQK[136.11].Y "sp|Q32P51|RA1L2_HUMAN,sp|P09651|ROA1_HUMAN,tr|A0A7I2YQX9|A0A7I2YQX9_HUMAN,tr|F8VZ49|F8VZ49_HUMAN,tr|A0A7I2V3R8|A0A7I2V3R8_HUMAN,tr|F8VTQ5|F8VTQ5_HUMAN,tr|F8W6I7|F8W6I7_HUMAN,tr|H0YH80|H0YH80_HUMAN,tr|A0A7I2V2L6|A0A7I2V2L6_HUMAN,tr|A0A7I2V3W0|A0A7I2V3W0_HUMAN,tr|A0A2R8Y4L2|A0A2R8Y4L2_HUMAN" 11 2296.171 1.26 54975 22229 4 2296.167427 575.05 Heterogeneous nuclear ribonucleoprotein A1-like 2 OS=Homo sapiens OX=9606 GN=HNRNPA1L2 PE=2 SV=2 4.56 3553.3 - 1.04E+07 - - - -1.5774 - 3.108 0.601 - 120.9 1 2 1 -0.0036 20 0 0 0 2.72E+08 2.15E+08 - - - 4.8352 0.9934 221125_WJC_METTL3_EV_vs_WT_F04.22230.22230.3 8.69E-10 17/76 K.GNPQGFNQGLDC[160.03]DVIVAEVR[166.11].S sp|Q86U44|MTA70_HUMAN 1 2197.0461 0.001 54976 22230 3 2198.0379 733.356 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 4.03 3553.4 - 1.72E+06 - - - 451.4079 - 3.133 0.62 - 324.8 1 2 0 0.9918 20 0 0 0 0.00E+00 3.52E+07 - - - 7.9482 1 221125_WJC_METTL3_EV_vs_WT_F04.22232.22232.3 9.84E-08 16/52 R.EYFSWEGAFQHVGK.A sp|P26641|EF1G_HUMAN 1 1683.7682 1.52 54978 22232 3 1683.76508 562.2633 Elongation factor 1-gamma OS=Homo sapiens OX=9606 GN=EEF1G PE=1 SV=3 5.4 3553.6 - 1.94E+06 - - - -1.8274 - 2.453 0.543 - 194.6 1 2 0 -0.0031 14 0 0 0 7.22E+07 4.75E+07 - - - 6.9777 0.998 221125_WJC_METTL3_EV_vs_WT_F04.22233.22233.2 0.242 14-Jul R.LTILELER[166.11].E sp|Q569K6|CC157_HUMAN 1 995.5891 0.001 54979 22233 2 995.587877 498.8018 Coiled-coil domain-containing protein 157 OS=Homo sapiens OX=9606 GN=CCDC157 PE=1 SV=3 4.53 3553.8 - 903764 - - - -1.1953 - 1.561 0.22 - 126.4 1 2 0 -0.0012 8 0 0 0 0.00E+00 7.68E+07 - - - 2.0086 0.9999 221125_WJC_METTL3_EV_vs_WT_F04.22235.22235.4 8.26E-08 13/114 R.GFAFVTFDDHDSVDKIVIQK.Y "sp|Q32P51|RA1L2_HUMAN,sp|P09651|ROA1_HUMAN,tr|A0A7I2YQX9|A0A7I2YQX9_HUMAN,tr|F8VZ49|F8VZ49_HUMAN,tr|A0A7I2V3R8|A0A7I2V3R8_HUMAN,tr|F8VTQ5|F8VTQ5_HUMAN,tr|F8W6I7|F8W6I7_HUMAN,tr|H0YH80|H0YH80_HUMAN,tr|A0A7I2V2L6|A0A7I2V2L6_HUMAN,tr|A0A7I2V3W0|A0A7I2V3W0_HUMAN,tr|A0A2R8Y4L2|A0A2R8Y4L2_HUMAN" 11 2280.1426 1.26 54980 22235 4 2280.141823 571.0429 Heterogeneous nuclear ribonucleoprotein A1-like 2 OS=Homo sapiens OX=9606 GN=HNRNPA1L2 PE=2 SV=2 4.56 3554 - 1.74E+07 - - - -0.3623 - 2.666 0.584 - 67.7 1 2 1 -0.0008 20 0 0 0 2.72E+08 2.15E+08 - - - 4.6367 0.9531 221125_WJC_METTL3_EV_vs_WT_F04.22239.22239.3 0.646 Nov-60 R.DGLKLMLLLEVISGER[166.11].L "sp|O43707|ACTN4_HUMAN,sp|P12814|ACTN1_HUMAN,tr|A0A804HK61|A0A804HK61_HUMAN,tr|A0A804HIN7|A0A804HIN7_HUMAN,tr|G3V5M4|G3V5M4_HUMAN,tr|A0A804HLF4|A0A804HLF4_HUMAN,tr|A0A804HIY0|A0A804HIY0_HUMAN,tr|A0A7I2V4Y4|A0A7I2V4Y4_HUMAN,tr|A0A804HII9|A0A804HII9_HUMAN,tr|A0A804HJQ9|A0A804HJQ9_HUMAN,tr|F5GXS2|F5GXS2_HUMAN,tr|A0A804HKE2|A0A804HKE2_HUMAN,tr|G3V2N5|G3V2N5_HUMAN,tr|A0A804HLD0|A0A804HLD0_HUMAN,tr|H7C144|H7C144_HUMAN" 15 1795.0153 - 54982 22239 3 1795.015899 599.3457 Alpha-actinin-4 OS=Homo sapiens OX=9606 GN=ACTN4 PE=1 SV=2 4.68 3554.4 - 6.40E+06 - - - 0.3465 - 1.943 0.137 - 163 1 2 1 0.0006 16 0 0 0 - - - - - 1.7716 0.9988 221125_WJC_METTL3_EV_vs_WT_F04.22241.22241.4 7.58E-05 19/126 K.AVLSAEQLR[166.11]DEEVHAGLGELLR[166.11].S "sp|P50454|SERPH_HUMAN,tr|E9PNX1|E9PNX1_HUMAN,tr|E9PIG2|E9PIG2_HUMAN,tr|E9PPV6|E9PPV6_HUMAN,tr|E9PR70|E9PR70_HUMAN,tr|E9PMI5|E9PMI5_HUMAN,tr|E9PRS3|E9PRS3_HUMAN,tr|E9PJH8|E9PJH8_HUMAN,tr|E9PK86|E9PK86_HUMAN,tr|E9PQ34|E9PQ34_HUMAN" 10 2424.2876 1.39 54984 22241 4 2424.280663 607.0792 Serpin H1 OS=Homo sapiens OX=9606 GN=SERPINH1 PE=1 SV=2 4.57 3554.7 - 2.14E+06 - - - -2.852 - 3.269 0.402 - 238.5 1 2 1 -0.0069 22 0 0 0 7.42E+07 5.34E+07 - - - 3.1107 1 221125_WJC_METTL3_EV_vs_WT_F04.22245.22245.3 9.84E-11 19/76 R.GFAFVTFDDHDSVDKIVIQK.Y "sp|Q32P51|RA1L2_HUMAN,sp|P09651|ROA1_HUMAN,tr|A0A7I2YQX9|A0A7I2YQX9_HUMAN,tr|F8VZ49|F8VZ49_HUMAN,tr|A0A7I2V3R8|A0A7I2V3R8_HUMAN,tr|F8VTQ5|F8VTQ5_HUMAN,tr|F8W6I7|F8W6I7_HUMAN,tr|H0YH80|H0YH80_HUMAN,tr|A0A7I2V2L6|A0A7I2V2L6_HUMAN,tr|A0A7I2V3W0|A0A7I2V3W0_HUMAN,tr|A0A2R8Y4L2|A0A2R8Y4L2_HUMAN" 11 2280.1426 0.83 54987 22245 3 2280.136509 761.0548 Heterogeneous nuclear ribonucleoprotein A1-like 2 OS=Homo sapiens OX=9606 GN=HNRNPA1L2 PE=2 SV=2 4.56 3555.1 - 7.35E+06 - - - -2.6928 - 3.614 0.621 - 311.5 1 2 1 -0.0061 20 0 0 0 1.20E+08 1.45E+08 - - - 8.5788 1 221125_WJC_METTL3_EV_vs_WT_F04.22247.22247.2 1.58E-09 15/30 K.SYELPDGQVITIGNER[166.11].F "sp|Q6S8J3|POTEE_HUMAN,sp|P63261|ACTG_HUMAN,sp|P68133|ACTS_HUMAN,sp|P62736|ACTA_HUMAN,sp|Q9BYX7|ACTBM_HUMAN,sp|P68032|ACTC_HUMAN,sp|Q562R1|ACTBL_HUMAN,sp|P60709|ACTB_HUMAN,sp|P63267|ACTH_HUMAN,sp|A5A3E0|POTEF_HUMAN,tr|A0A804GS07|A0A804GS07_HUMAN,tr|E7EVS6|E7EVS6_HUMAN,tr|A0A6Q8PFE4|A0A6Q8PFE4_HUMAN,tr|A0A2R8YEA7|A0A2R8YEA7_HUMAN,tr|A0A804HKV3|A0A804HKV3_HUMAN,tr|A0A2R8Y793|A0A2R8Y793_HUMAN,tr|I3L4N8|I3L4N8_HUMAN,tr|A6NL76|A6NL76_HUMAN" 18 1799.8929 1.07 54988 22247 2 1799.889106 900.9537 POTE ankyrin domain family member E OS=Homo sapiens OX=9606 GN=POTEE PE=2 SV=3 4.14 3555.4 - 9.48E+06 - - - -2.1151 - 2.986 0.664 - 672 1 2 0 -0.0038 16 0 0 0 2.36E+09 2.20E+09 - - - 6.6336 1 221125_WJC_METTL3_EV_vs_WT_F04.22248.22248.3 7.16E-14 18/60 K.SYELPDGQVITIGNER.F "sp|Q6S8J3|POTEE_HUMAN,sp|P63261|ACTG_HUMAN,sp|P68133|ACTS_HUMAN,sp|P62736|ACTA_HUMAN,sp|Q9BYX7|ACTBM_HUMAN,sp|P68032|ACTC_HUMAN,sp|Q562R1|ACTBL_HUMAN,sp|P60709|ACTB_HUMAN,sp|P63267|ACTH_HUMAN,sp|A5A3E0|POTEF_HUMAN,tr|A0A804GS07|A0A804GS07_HUMAN,tr|E7EVS6|E7EVS6_HUMAN,tr|A0A6Q8PFE4|A0A6Q8PFE4_HUMAN,tr|A0A2R8YEA7|A0A2R8YEA7_HUMAN,tr|A0A804HKV3|A0A804HKV3_HUMAN,tr|A0A2R8Y793|A0A2R8Y793_HUMAN,tr|I3L4N8|I3L4N8_HUMAN,tr|A6NL76|A6NL76_HUMAN" 18 1789.8846 1.05 54989 22248 3 1789.882948 597.6355 POTE ankyrin domain family member E OS=Homo sapiens OX=9606 GN=POTEE PE=2 SV=3 4.14 3555.4 - 4.99E+06 - - - -0.947 - 3.205 0.679 - 414.7 1 2 0 -0.0017 16 0 0 0 6.23E+08 5.94E+08 - - - 9.0982 0.9788 221125_WJC_METTL3_EV_vs_WT_F04.22250.22250.3 1.10E-05 18/60 R.R[166.11]AEQDSTTVAAFASSL.V "sp|Q86U44|MTA70_HUMAN,tr|F5H6D8|F5H6D8_HUMAN,tr|H0YFV6|H0YFV6_HUMAN,tr|B4DTN4|B4DTN4_HUMAN" 4 1662.8088 0 54991 22250 3 1662.802309 555.2769 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 4.37 3555.6 - 2.15E+06 - - - -3.9331 - 2.94 0.476 - 320.8 1 1 0 -0.0065 16 0 0 0 2.23E+05 2.17E+08 - - - 6.6122 1 221125_WJC_METTL3_EV_vs_WT_F04.22256.22256.3 8.27E-05 23/60 R.HGVQELEIELQSQLSK.K "sp|P35527|K1C9_HUMAN,tr|K7EQQ3|K7EQQ3_HUMAN" 2 1836.9581 11885.05 54995 22256 3 1836.957378 613.3267 "Keratin, type I cytoskeletal 9 OS=Homo sapiens OX=9606 GN=KRT9 PE=1 SV=3" 4.75 3556.2 - 2.89E+06 - - - -0.4159 - 2.448 0.504 - 158.7 1 2 0 -0.0008 16 0 0 0 1.75E+10 1.47E+06 - - - 6.456 1 221125_WJC_METTL3_EV_vs_WT_F04.22257.22257.2 2.11E-06 13/30 R.RAEQDSTTVAAFASSL.V "sp|Q86U44|MTA70_HUMAN,tr|F5H6D8|F5H6D8_HUMAN,tr|H0YFV6|H0YFV6_HUMAN,tr|B4DTN4|B4DTN4_HUMAN" 4 1652.8006 0.02 54996 22257 2 1652.793752 827.4076 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 4.37 3556.3 - 1.59E+06 - - - -4.1306 - 2.687 0.583 - 292.7 1 1 0 -0.0068 16 0 0 0 1.65E+08 8.34E+09 - - - 5.775 1 221125_WJC_METTL3_EV_vs_WT_F04.22271.22271.3 8.24E-12 24/84 K.KPALGFYDTSEENYQALDADFR.K sp|Q99459|CDC5L_HUMAN 1 2549.171 0.63 55002 22271 3 2549.175235 850.731 Cell division cycle 5-like protein OS=Homo sapiens OX=9606 GN=CDC5L PE=1 SV=2 4.11 3558.1 - 1.80E+06 - - - 1.6425 - 3.807 0.669 - 638.6 1 2 0 0.0042 22 0 0 0 4.67E+07 7.36E+07 - - - 9.167 1 221125_WJC_METTL3_EV_vs_WT_F04.22277.22277.2 4.93E-14 25/30 R.HGVQELEIELQSQLSK.K "sp|P35527|K1C9_HUMAN,tr|K7EQQ3|K7EQQ3_HUMAN" 2 1836.9581 999 55005 22277 2 1836.958717 919.4863 "Keratin, type I cytoskeletal 9 OS=Homo sapiens OX=9606 GN=KRT9 PE=1 SV=3" 4.75 3558.8 - 5.80E+06 - - - 0.313 - 5.458 0.727 - 2559.6 1 2 0 0.0006 16 0 0 0 4.22E+09 0.00E+00 - - - 8.5828 1 221125_WJC_METTL3_EV_vs_WT_F04.22294.22294.3 1.85E-07 19/60 K.SYELPDGQVITIGNER[166.11].F "sp|Q6S8J3|POTEE_HUMAN,sp|P63261|ACTG_HUMAN,sp|P68133|ACTS_HUMAN,sp|P62736|ACTA_HUMAN,sp|Q9BYX7|ACTBM_HUMAN,sp|P68032|ACTC_HUMAN,sp|Q562R1|ACTBL_HUMAN,sp|P60709|ACTB_HUMAN,sp|P63267|ACTH_HUMAN,sp|A5A3E0|POTEF_HUMAN,tr|A0A804GS07|A0A804GS07_HUMAN,tr|E7EVS6|E7EVS6_HUMAN,tr|A0A6Q8PFE4|A0A6Q8PFE4_HUMAN,tr|A0A2R8YEA7|A0A2R8YEA7_HUMAN,tr|A0A804HKV3|A0A804HKV3_HUMAN,tr|A0A2R8Y793|A0A2R8Y793_HUMAN,tr|I3L4N8|I3L4N8_HUMAN,tr|A6NL76|A6NL76_HUMAN" 18 1799.8929 1.05 55013 22294 3 1799.892145 600.9716 POTE ankyrin domain family member E OS=Homo sapiens OX=9606 GN=POTEE PE=2 SV=3 4.14 3560.9 - 5.28E+06 - - - -0.4267 - 2.96 0.626 - 424.6 1 2 0 -0.0008 16 0 0 0 6.24E+08 5.96E+08 - - - 8.3035 1 221125_WJC_METTL3_EV_vs_WT_F04.22301.22301.3 2.42E-13 26/84 R.TVYGGGC[160.03]SEMLMAHAVTQLANR[166.11].T "sp|P78371|TCPB_HUMAN,tr|F5GWF6|F5GWF6_HUMAN" 2 2375.106 0.26 55015 22301 3 2376.10405 792.7093 T-complex protein 1 subunit beta OS=Homo sapiens OX=9606 GN=CCT2 PE=1 SV=4 6.41 3561.9 - 4.59E+06 - - - 420.2229 - 4.148 0.69 - 501.4 1 2 0 0.9981 22 0 0 0 8.94E+07 3.41E+08 - - - 9.3292 0.9999 221125_WJC_METTL3_EV_vs_WT_F04.22326.22326.3 6.56E-08 21/84 K.DSGPLPTPPGVSLLGEPPKDYR.L "tr|E9PAU2|E9PAU2_HUMAN,tr|A0A087WZ13|A0A087WZ13_HUMAN" 2 2291.1798 1.14 55022 22326 3 2291.17924 764.7339 Ribonucleoprotein PTB-binding 1 OS=Homo sapiens OX=9606 GN=RAVER1 PE=1 SV=1 4.56 3565.4 - 3.89E+06 - - - -0.2278 - 3.398 0.514 - 275.1 1 2 1 -0.0005 22 0 0 0 9.92E+07 8.73E+07 - - - 7.1704 0.9943 221125_WJC_METTL3_EV_vs_WT_F04.22332.22332.3 0.00144 18/52 K.LLHHLSDLALTLPT.D "sp|Q86U44|MTA70_HUMAN,tr|B4E349|B4E349_HUMAN,tr|F5H6D8|F5H6D8_HUMAN,tr|H0YFV6|H0YFV6_HUMAN,tr|B4DTN4|B4DTN4_HUMAN" 5 1542.877 - 55024 22332 3 1542.875061 515.2996 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 5.97 3566.2 - 2.91E+06 - - - -1.2431 - 3.182 0.388 - 322.9 1 1 0 -0.0019 14 0 0 0 - - - - - 5.9414 1 221125_WJC_METTL3_EV_vs_WT_F04.22341.22341.2 3.00E-10 16/28 L.SFDTNEQSLEQVFSK.Y "sp|Q14011|CIRBP_HUMAN,tr|K7ER40|K7ER40_HUMAN,tr|K7EQL0|K7EQL0_HUMAN,tr|K7ENX8|K7ENX8_HUMAN,tr|K7EJV1|K7EJV1_HUMAN,tr|K7EJV5|K7EJV5_HUMAN,tr|K7ELT6|K7ELT6_HUMAN,tr|K7EIF7|K7EIF7_HUMAN,tr|K7EMY9|K7EMY9_HUMAN,tr|K7EQX4|K7EQX4_HUMAN,tr|K7ELV6|K7ELV6_HUMAN,tr|K7EQR7|K7EQR7_HUMAN,tr|K7EPM4|K7EPM4_HUMAN,tr|K7ENN6|K7ENN6_HUMAN,tr|D6W5Y5|D6W5Y5_HUMAN" 15 1757.8108 1.13 55026 22341 2 1757.806134 879.9127 Cold-inducible RNA-binding protein OS=Homo sapiens OX=9606 GN=CIRBP PE=1 SV=1 4.14 3567.5 - 2.05E+06 - - - -2.6596 - 3.328 0.645 - 797.6 1 1 0 -0.0047 15 0 0 0 1.10E+08 9.73E+07 - - - 6.7596 1 221125_WJC_METTL3_EV_vs_WT_F04.22343.22343.3 1.05E-12 20/84 R.TVYGGGC[160.03]SEMLMAHAVTQLANR.T "sp|P78371|TCPB_HUMAN,tr|F5GWF6|F5GWF6_HUMAN" 2 2365.0977 0.26 55027 22343 3 2365.087714 789.3732 T-complex protein 1 subunit beta OS=Homo sapiens OX=9606 GN=CCT2 PE=1 SV=4 6.41 3567.7 - 3.32E+06 - - - -4.2248 - 3.759 0.739 - 336.8 1 2 0 -0.01 22 0 0 0 8.94E+07 3.41E+08 - - - 9.9157 1 221125_WJC_METTL3_EV_vs_WT_F04.22346.22346.2 1.02E-12 17/28 L.SFDTNEQSLEQVFSK[136.11].Y "sp|Q14011|CIRBP_HUMAN,tr|K7ER40|K7ER40_HUMAN,tr|K7EQL0|K7EQL0_HUMAN,tr|K7ENX8|K7ENX8_HUMAN,tr|K7EJV1|K7EJV1_HUMAN,tr|K7EJV5|K7EJV5_HUMAN,tr|K7ELT6|K7ELT6_HUMAN,tr|K7EIF7|K7EIF7_HUMAN,tr|K7EMY9|K7EMY9_HUMAN,tr|K7EQX4|K7EQX4_HUMAN,tr|K7ELV6|K7ELV6_HUMAN,tr|K7EQR7|K7EQR7_HUMAN,tr|K7EPM4|K7EPM4_HUMAN,tr|K7ENN6|K7ENN6_HUMAN,tr|D6W5Y5|D6W5Y5_HUMAN" 15 1765.825 1.13 55028 22346 2 1765.82092 883.9198 Cold-inducible RNA-binding protein OS=Homo sapiens OX=9606 GN=CIRBP PE=1 SV=1 4.14 3568.1 - 2.95E+06 - - - -2.3156 - 3.424 0.649 - 927.3 1 1 0 -0.0041 15 0 0 0 1.10E+08 9.73E+07 - - - 6.8592 0.9981 221125_WJC_METTL3_EV_vs_WT_F04.22347.22347.3 3.28E-07 14/56 L.SFDTNEQSLEQVFSK[136.11].Y "sp|Q14011|CIRBP_HUMAN,tr|K7ER40|K7ER40_HUMAN,tr|K7EQL0|K7EQL0_HUMAN,tr|K7ENX8|K7ENX8_HUMAN,tr|K7EJV1|K7EJV1_HUMAN,tr|K7EJV5|K7EJV5_HUMAN,tr|K7ELT6|K7ELT6_HUMAN,tr|K7EIF7|K7EIF7_HUMAN,tr|K7EMY9|K7EMY9_HUMAN,tr|K7EQX4|K7EQX4_HUMAN,tr|K7ELV6|K7ELV6_HUMAN,tr|K7EQR7|K7EQR7_HUMAN,tr|K7EPM4|K7EPM4_HUMAN,tr|K7ENN6|K7ENN6_HUMAN,tr|D6W5Y5|D6W5Y5_HUMAN" 15 1765.825 1.04 55029 22347 3 1765.823371 589.6156 Cold-inducible RNA-binding protein OS=Homo sapiens OX=9606 GN=CIRBP PE=1 SV=1 4.14 3568.2 - 841617 - - - -0.9276 - 2.623 0.553 - 214.2 1 1 0 -0.0016 15 0 0 0 3.63E+07 3.49E+07 - - - 7.2212 1 221125_WJC_METTL3_EV_vs_WT_F04.22359.22359.3 2.23E-07 20/68 K.LVINGNPITIFQERDPSK.L sp|P04406|G3P_HUMAN 1 2040.1004 1.09 55035 22359 3 2040.100895 681.0407 Glyceraldehyde-3-phosphate dehydrogenase OS=Homo sapiens OX=9606 GN=GAPDH PE=1 SV=3 6.07 3569.6 - 3.10E+06 - - - 0.2475 - 3.797 0.589 - 385.5 1 2 1 0.0005 18 0 0 0 5.82E+09 5.35E+09 - - - 8.429 0.9936 221125_WJC_METTL3_EV_vs_WT_F04.22361.22361.3 1.19E-07 13/56 L.SFDTNEQSLEQVFSK.Y "sp|Q14011|CIRBP_HUMAN,tr|K7ER40|K7ER40_HUMAN,tr|K7EQL0|K7EQL0_HUMAN,tr|K7ENX8|K7ENX8_HUMAN,tr|K7EJV1|K7EJV1_HUMAN,tr|K7EJV5|K7EJV5_HUMAN,tr|K7ELT6|K7ELT6_HUMAN,tr|K7EIF7|K7EIF7_HUMAN,tr|K7EMY9|K7EMY9_HUMAN,tr|K7EQX4|K7EQX4_HUMAN,tr|K7ELV6|K7ELV6_HUMAN,tr|K7EQR7|K7EQR7_HUMAN,tr|K7EPM4|K7EPM4_HUMAN,tr|K7ENN6|K7ENN6_HUMAN,tr|D6W5Y5|D6W5Y5_HUMAN" 15 1757.8108 1.04 55036 22361 3 1757.805742 586.9442 Cold-inducible RNA-binding protein OS=Homo sapiens OX=9606 GN=CIRBP PE=1 SV=1 4.14 3569.8 - 1.94E+06 - - - -2.8826 - 2.333 0.582 - 172.6 1 1 0 -0.0051 15 0 0 0 3.63E+07 3.49E+07 - - - 7.2379 0.9999 221125_WJC_METTL3_EV_vs_WT_F04.22363.22363.3 1.08E-07 19/68 K.LVINGNPITIFQER[166.11]DPSK[136.11].L sp|P04406|G3P_HUMAN 1 2058.1229 1.09 55037 22363 3 2058.120024 687.0482 Glyceraldehyde-3-phosphate dehydrogenase OS=Homo sapiens OX=9606 GN=GAPDH PE=1 SV=3 6.07 3570 - 4.99E+06 - - - -1.378 - 3.279 0.62 - 377.4 1 2 1 -0.0028 18 0 0 0 5.82E+09 5.35E+09 - - - 8.4087 0.999 221125_WJC_METTL3_EV_vs_WT_F04.22370.22370.3 0.0857 13/60 K.K[136.11]VSQEILELLNTTTAK[136.11].E "sp|Q86U44|MTA70_HUMAN,tr|H0YFV6|H0YFV6_HUMAN" 2 1803.0324 0 55041 22370 3 1803.029497 602.0181 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 6.14 3570.9 - 3.13E+06 - - - -1.6267 - 2.131 0.276 - 230 1 2 0 -0.0029 16 0 0 0 3.81E+05 2.80E+08 - - - 3.5576 1 221125_WJC_METTL3_EV_vs_WT_F04.22374.22374.3 5.19E-10 21/72 K.YK[136.11]DLDEDELLGNLSETELK[136.11].Q "sp|Q9NYL9|TMOD3_HUMAN,tr|H0YNU8|H0YNU8_HUMAN" 2 2239.1078 0.34 55043 22374 3 2239.106774 747.3766 Tropomodulin-3 OS=Homo sapiens OX=9606 GN=TMOD3 PE=1 SV=1 3.95 3571.4 - 2.01E+06 - - - -0.4756 - 3.803 0.583 - 659.9 1 2 1 -0.0011 19 0 0 0 3.04E+07 9.00E+07 - - - 8.3214 1 221125_WJC_METTL3_EV_vs_WT_F04.22377.22377.3 6.72E-06 19/56 K.HSGNITFDEIVNIAR[166.11].Q sp|P30050|RL12_HUMAN 1 1694.8616 1.44 55045 22377 3 1694.86054 565.9611 60S ribosomal protein L12 OS=Homo sapiens OX=9606 GN=RPL12 PE=1 SV=1 5.32 3571.8 - 1.07E+06 - - - -0.5977 - 2.381 0.51 - 313.9 1 2 0 -0.001 15 0 0 0 1.54E+09 1.07E+09 - - - 6.4894 1 221125_WJC_METTL3_EV_vs_WT_F04.22379.22379.3 4.13E-08 19/56 K.HSGNITFDEIVNIAR.Q sp|P30050|RL12_HUMAN 1 1684.8533 1.44 55047 22379 3 1684.852753 562.625 60S ribosomal protein L12 OS=Homo sapiens OX=9606 GN=RPL12 PE=1 SV=1 5.32 3572 - 1.57E+06 - - - -0.3146 - 2.916 0.603 - 274.7 1 2 0 -0.0005 15 0 0 0 1.54E+09 1.07E+09 - - - 8.0553 0.9959 221125_WJC_METTL3_EV_vs_WT_F04.22380.22380.3 0.000686 Sep-44 R.GFKDQIYDIFQK.L "sp|P60842|IF4A1_HUMAN,tr|J3KTB5|J3KTB5_HUMAN,tr|J3KT12|J3KT12_HUMAN,tr|J3QS69|J3QS69_HUMAN,tr|J3QL43|J3QL43_HUMAN,tr|J3KTN0|J3KTN0_HUMAN,tr|J3KSZ0|J3KSZ0_HUMAN,tr|J3QR64|J3QR64_HUMAN" 8 1500.7613 1.35 55048 22380 3 1500.760752 501.261 Eukaryotic initiation factor 4A-I OS=Homo sapiens OX=9606 GN=EIF4A1 PE=1 SV=1 5.96 3572.1 - 709688 - - - -0.3518 - 1.967 0.267 - 82.4 1 2 1 -0.0005 12 0 0 0 2.10E+07 1.56E+07 - - - 3.3918 1 221125_WJC_METTL3_EV_vs_WT_F04.22384.22384.3 6.18E-07 13/72 K.VGDFGDAINWPTPGEIAHK[136.11].S "sp|Q6PKG0|LARP1_HUMAN,tr|A0A0B4J210|A0A0B4J210_HUMAN,tr|H0YAX9|H0YAX9_HUMAN" 3 2030.9941 0.87 55050 22384 3 2030.992281 678.0053 La-related protein 1 OS=Homo sapiens OX=9606 GN=LARP1 PE=1 SV=2 4.54 3572.6 - 473037 - - - -0.9153 - 2.273 0.495 - 153 1 2 0 -0.0019 19 0 0 0 2.89E+07 3.32E+07 - - - 6.0755 0.9592 221125_WJC_METTL3_EV_vs_WT_F04.22399.22399.3 1.03E-05 25/96 K.IDSIPHLNNSTPLVDPSVYGYGVQK.R sp|Q96I24|FUBP3_HUMAN 1 2712.3759 -1 55060 22399 3 2713.357651 905.1326 Far upstream element-binding protein 3 OS=Homo sapiens OX=9606 GN=FUBP3 PE=1 SV=2 5.21 3574.3 - 2.08E+06 - - - 361.9539 - 3.606 0.578 - 569.8 1 2 0 0.9818 25 0 0 0 0.00E+00 0.00E+00 - - - 7.663 1 221125_WJC_METTL3_EV_vs_WT_F04.22403.22403.3 3.82E-08 19/72 K.VGDFGDAINWPTPGEIAHK.S "sp|Q6PKG0|LARP1_HUMAN,tr|A0A0B4J210|A0A0B4J210_HUMAN,tr|H0YAX9|H0YAX9_HUMAN" 3 2022.9799 0.91 55064 22403 3 2022.976223 675.3339 La-related protein 1 OS=Homo sapiens OX=9606 GN=LARP1 PE=1 SV=2 4.54 3574.7 - 690437 - - - -1.8374 - 3.068 0.545 - 341.2 1 2 0 -0.0037 19 0 0 0 2.66E+07 2.92E+07 - - - 7.3693 1 221125_WJC_METTL3_EV_vs_WT_F04.22406.22406.2 2.28E-09 20/28 K.HSGNITFDEIVNIAR.Q sp|P30050|RL12_HUMAN 1 1684.8533 1.49 55065 22406 2 1684.85508 843.4339 60S ribosomal protein L12 OS=Homo sapiens OX=9606 GN=RPL12 PE=1 SV=1 5.32 3575.1 - 1.92E+06 - - - 1.0666 - 3.631 0.638 - 1177.2 1 2 0 0.0018 15 0 0 0 1.82E+08 1.22E+08 - - - 6.923 1 221125_WJC_METTL3_EV_vs_WT_F04.22408.22408.2 2.66E-08 20/28 K.HSGNITFDEIVNIAR[166.11].Q sp|P30050|RL12_HUMAN 1 1694.8616 1.49 55067 22408 2 1694.861062 848.4381 60S ribosomal protein L12 OS=Homo sapiens OX=9606 GN=RPL12 PE=1 SV=1 5.32 3575.4 - 2.12E+06 - - - -0.2897 - 3.702 0.654 - 1346.7 1 2 0 -0.0005 15 0 0 0 1.82E+08 1.22E+08 - - - 7.0892 1 221125_WJC_METTL3_EV_vs_WT_F04.22410.22410.3 1.01E-07 21/76 K.TIDGQQTIIAC[160.03]IESHQFQPK.N sp|P52907|CAZA1_HUMAN 1 2313.1423 1.08 55069 22410 3 2313.143101 772.0547 F-actin-capping protein subunit alpha-1 OS=Homo sapiens OX=9606 GN=CAPZA1 PE=1 SV=3 5.29 3575.6 - 1.40E+06 - - - 0.3329 - 4.078 0.563 - 244.1 1 2 0 0.0008 20 0 0 0 1.27E+07 1.18E+07 - - - 8.2267 1 221125_WJC_METTL3_EV_vs_WT_F04.22411.22411.2 2.02E-13 17/32 K.DGLNDDDFEPYLSPQAR.P "sp|Q9Y5A9|YTHD2_HUMAN,tr|S4R3J8|S4R3J8_HUMAN" 2 1950.8595 1.69 55070 22411 2 1950.859619 976.4371 YTH domain-containing family protein 2 OS=Homo sapiens OX=9606 GN=YTHDF2 PE=1 SV=2 3.71 3575.8 - 1.22E+06 - - - 0.0354 - 3.107 0.637 - 538.1 1 1 0 0.0001 17 0 0 0 8.65E+07 5.13E+07 - - - 6.533 1 221125_WJC_METTL3_EV_vs_WT_F04.22412.22412.2 1.53E-10 17/32 K.DGLNDDDFEPYLSPQAR[166.11].P "sp|Q9Y5A9|YTHD2_HUMAN,tr|S4R3J8|S4R3J8_HUMAN" 2 1960.8678 1.69 55071 22412 2 1960.865952 981.4412 YTH domain-containing family protein 2 OS=Homo sapiens OX=9606 GN=YTHDF2 PE=1 SV=2 3.71 3575.9 - 1.17E+06 - - - -0.9526 - 3.263 0.658 - 624.7 1 1 0 -0.0019 17 0 0 0 8.65E+07 5.13E+07 - - - 6.808 0.9998 221125_WJC_METTL3_EV_vs_WT_F04.22413.22413.4 2.18E-06 19/126 R.THPVEIFYTPEPERDYLEAAIR.T sp|O43143|DHX15_HUMAN 1 2645.3126 2.38 55072 22413 4 2645.309771 662.3354 Pre-mRNA-splicing factor ATP-dependent RNA helicase DHX15 OS=Homo sapiens OX=9606 GN=DHX15 PE=1 SV=2 4.57 3576 - 809957 - - - -1.0573 - 2.539 0.466 - 195 1 2 1 -0.0028 22 0 0 0 2.23E+07 9.37E+06 - - - 3.5862 0.9998 221125_WJC_METTL3_EV_vs_WT_F04.22414.22414.3 1.53E-05 13/60 R.RFDEILEASDGIMVAR.G "sp|P14618|KPYM_HUMAN,tr|B4DNK4|B4DNK4_HUMAN,tr|A0A804F6T5|A0A804F6T5_HUMAN,tr|H3BTN5|H3BTN5_HUMAN,tr|H3BR70|H3BR70_HUMAN,tr|A0A804F729|A0A804F729_HUMAN" 6 1820.9091 10.49 55073 22414 3 1820.91286 607.977 Pyruvate kinase PKM OS=Homo sapiens OX=9606 GN=PKM PE=1 SV=4 4.32 3576.2 - 611545 - - - 2.0737 - 2.43 0.417 - 228.4 1 2 0 0.0038 16 0 0 0 4.20E+07 4.01E+06 - - - 5.4663 0.9968 221125_WJC_METTL3_EV_vs_WT_F04.22420.22420.3 9.45E-10 17/64 K.DGLNDDDFEPYLSPQAR.P "sp|Q9Y5A9|YTHD2_HUMAN,tr|S4R3J8|S4R3J8_HUMAN" 2 1950.8595 1.57 55077 22420 3 1950.859768 651.2938 YTH domain-containing family protein 2 OS=Homo sapiens OX=9606 GN=YTHDF2 PE=1 SV=2 3.71 3576.8 - 1.18E+06 - - - 0.1117 - 2.434 0.511 - 356 1 1 0 0.0002 17 0 0 0 4.26E+07 2.72E+07 - - - 6.4843 1 221125_WJC_METTL3_EV_vs_WT_F04.22421.22421.3 1.96E-10 21/64 K.DGLNDDDFEPYLSPQAR[166.11].P "sp|Q9Y5A9|YTHD2_HUMAN,tr|S4R3J8|S4R3J8_HUMAN" 2 1960.8678 1.6 55078 22421 3 1960.870711 654.6299 YTH domain-containing family protein 2 OS=Homo sapiens OX=9606 GN=YTHDF2 PE=1 SV=2 3.71 3576.9 - 1.09E+06 - - - 1.4743 - 3.35 0.682 - 639.8 1 1 0 0.0029 17 0 0 0 4.26E+07 2.66E+07 - - - 9.197 1 221125_WJC_METTL3_EV_vs_WT_F04.22422.22422.3 2.28E-05 14/80 R.LQEVPHEGPMC[160.03]DLLWSDPDDR.G "sp|P67775|PP2AA_HUMAN,sp|P62714|PP2AB_HUMAN,tr|E5RHC1|E5RHC1_HUMAN,tr|H0YC23|H0YC23_HUMAN" 4 2508.105 0.44 55079 22422 3 2508.105475 837.0423 Serine\threonine-protein phosphatase 2A catalytic subunit alpha isoform OS=Homo sapiens OX=9606 GN=PPP2CA PE=1 SV=1 3.96 3577.1 - 1.05E+06 - - - 0.2053 - 2.816 0.541 - 151.1 1 2 0 0.0005 21 0 0 0 1.08E+07 2.45E+07 - - - 7.0536 1 221125_WJC_METTL3_EV_vs_WT_F04.22423.22423.2 1.26E-06 16/34 K.SSGPTSLFAVTVAPPGAR[166.11].Q "sp|Q00839|HNRPU_HUMAN,tr|A0A1W2PP35|A0A1W2PP35_HUMAN,tr|A0A1W2PPS1|A0A1W2PPS1_HUMAN,tr|A0A1W2PP22|A0A1W2PP22_HUMAN,tr|A0A1X7SBS1|A0A1X7SBS1_HUMAN" 5 1723.9133 1.02 55080 22423 2 1723.917137 862.9639 Heterogeneous nuclear ribonucleoprotein U OS=Homo sapiens OX=9606 GN=HNRNPU PE=1 SV=6 9.47 3577.2 - 1.04E+06 - - - 2.2524 - 3.094 0.552 - 749.1 1 2 0 0.0039 18 0 0 0 2.84E+08 2.77E+08 - - - 5.8937 1 221125_WJC_METTL3_EV_vs_WT_F04.22428.22428.3 1.81E-13 18/64 R.SHEAIINYTSELFYEGK.L "sp|P42694|HELZ_HUMAN,tr|J3QS41|J3QS41_HUMAN" 2 1999.9527 0.81 55083 22428 3 1999.953984 667.6582 Probable helicase with zinc finger domain OS=Homo sapiens OX=9606 GN=HELZ PE=1 SV=2 4.75 3577.9 - 3.00E+06 - - - 0.6305 - 3.747 0.695 - 516.2 1 2 0 0.0013 17 0 0 0 3.59E+07 4.45E+07 - - - 9.6253 1 221125_WJC_METTL3_EV_vs_WT_F04.22429.22429.4 1.54E-11 30/138 K.TFEHVTSEIGAEEAEEVGVEHLLR[166.11].D "sp|P51665|PSMD7_HUMAN,tr|H3BNT7|H3BNT7_HUMAN,tr|H3BTM8|H3BTM8_HUMAN" 3 2690.3063 0.63 55084 22429 4 2690.308606 673.5839 26S proteasome non-ATPase regulatory subunit 7 OS=Homo sapiens OX=9606 GN=PSMD7 PE=1 SV=2 4.35 3577.9 - 3.54E+06 - - - 0.8534 - 4.914 0.668 - 514.7 1 2 0 0.0023 24 0 0 0 2.02E+07 3.19E+07 - - - 5.5506 0.9052 221125_WJC_METTL3_EV_vs_WT_F04.22430.22430.3 2.61E-05 22/96 K.IDSIPHLNNSTPLVDPSVYGYGVQK[136.11].R sp|Q96I24|FUBP3_HUMAN 1 2720.3901 0.001 55085 22430 3 2721.371083 907.804 Far upstream element-binding protein 3 OS=Homo sapiens OX=9606 GN=FUBP3 PE=1 SV=2 5.21 3578.1 - 3.21E+06 - - - 360.6053 - 3.417 0.483 - 436.6 1 2 0 0.981 25 0 0 0 0.00E+00 6.40E+06 - - - 6.4802 1 221125_WJC_METTL3_EV_vs_WT_F04.22432.22432.4 2.72E-10 24/138 K.TFEHVTSEIGAEEAEEVGVEHLLR.D "sp|P51665|PSMD7_HUMAN,tr|H3BNT7|H3BNT7_HUMAN,tr|H3BTM8|H3BTM8_HUMAN" 3 2680.298 0.64 55087 22432 4 2680.298148 671.0818 26S proteasome non-ATPase regulatory subunit 7 OS=Homo sapiens OX=9606 GN=PSMD7 PE=1 SV=2 4.35 3578.2 - 2.52E+06 - - - 0.0403 - 4.244 0.619 - 332.8 1 2 0 0.0001 24 0 0 0 2.04E+07 3.21E+07 - - - 5.0777 1 221125_WJC_METTL3_EV_vs_WT_F04.22436.22436.2 6.84E-11 20/34 K.LVINGNPITIFQER[166.11]DPSK[136.11].L sp|P04406|G3P_HUMAN 1 2058.1229 1.13 55091 22436 2 2058.12102 1030.0687 Glyceraldehyde-3-phosphate dehydrogenase OS=Homo sapiens OX=9606 GN=GAPDH PE=1 SV=3 6.07 3578.7 - 1.62E+06 - - - -0.894 - 4.023 0.568 - 1042.9 1 2 1 -0.0018 18 0 0 0 1.11E+08 9.78E+07 - - - 6.658 1 221125_WJC_METTL3_EV_vs_WT_F04.22442.22442.2 7.64E-11 23/34 K.LVINGNPITIFQERDPSK.L sp|P04406|G3P_HUMAN 1 2040.1004 1.13 55095 22442 2 2040.099386 1021.0575 Glyceraldehyde-3-phosphate dehydrogenase OS=Homo sapiens OX=9606 GN=GAPDH PE=1 SV=3 6.07 3579.4 - 2.87E+06 - - - -0.4921 - 4.102 0.691 - 1579.4 1 2 1 -0.001 18 0 0 0 1.11E+08 9.78E+07 - - - 7.6146 1 221125_WJC_METTL3_EV_vs_WT_F04.22443.22443.2 1.17E-10 19/34 K.SSGPTSLFAVTVAPPGAR.Q "sp|Q00839|HNRPU_HUMAN,tr|A0A1W2PP35|A0A1W2PP35_HUMAN,tr|A0A1W2PPS1|A0A1W2PPS1_HUMAN,tr|A0A1W2PP22|A0A1W2PP22_HUMAN,tr|A0A1X7SBS1|A0A1X7SBS1_HUMAN" 5 1713.905 1.03 55096 22443 2 1713.906411 857.9598 Heterogeneous nuclear ribonucleoprotein U OS=Homo sapiens OX=9606 GN=HNRNPU PE=1 SV=6 9.47 3579.6 - 2.41E+06 - - - 0.8326 - 2.981 0.601 - 999.4 1 2 0 0.0014 18 0 0 0 2.84E+08 2.76E+08 - - - 6.1649 1 221125_WJC_METTL3_EV_vs_WT_F04.22448.22448.3 4.69E-08 21/60 R.TSQEELLAEVVQGQSR[166.11].T "sp|Q6PJT7|ZC3HE_HUMAN,tr|G3V256|G3V256_HUMAN,tr|G3V5I6|G3V5I6_HUMAN,tr|H0YJA2|H0YJA2_HUMAN,tr|A0A087WTC9|A0A087WTC9_HUMAN" 5 1782.8987 1.19 55101 22448 3 1782.900085 595.3069 Zinc finger CCCH domain-containing protein 14 OS=Homo sapiens OX=9606 GN=ZC3H14 PE=1 SV=1 4.25 3580.2 - 1.27E+06 - - - 0.7617 - 3.429 0.485 - 656.2 1 2 0 0.0014 16 0 0 0 3.20E+07 2.68E+07 - - - 7.1087 1 221125_WJC_METTL3_EV_vs_WT_F04.22458.22458.3 6.70E-08 17/60 R.TSQEELLAEVVQGQSR.T "sp|Q6PJT7|ZC3HE_HUMAN,tr|G3V256|G3V256_HUMAN,tr|G3V5I6|G3V5I6_HUMAN,tr|H0YJA2|H0YJA2_HUMAN,tr|A0A087WTC9|A0A087WTC9_HUMAN" 5 1772.8905 1.19 55109 22458 3 1772.891109 591.9708 Zinc finger CCCH domain-containing protein 14 OS=Homo sapiens OX=9606 GN=ZC3H14 PE=1 SV=1 4.25 3581.3 - 1.97E+06 - - - 0.3678 - 3.263 0.497 - 349.6 1 2 0 0.0007 16 0 0 0 3.20E+07 2.68E+07 - - - 7.1154 0.9969 221125_WJC_METTL3_EV_vs_WT_F04.22459.22459.3 1.96E-09 20/88 R.QTASVTLQAIAAQNAAVQAVNAH.S "sp|Q16891|MIC60_HUMAN,tr|B9A067|B9A067_HUMAN,tr|C9J406|C9J406_HUMAN,tr|H7C463|H7C463_HUMAN" 4 2276.1873 - 55110 22459 3 2276.183485 759.7364 MICOS complex subunit MIC60 OS=Homo sapiens OX=9606 GN=IMMT PE=1 SV=1 6.74 3581.4 - 1.73E+06 - - - -1.6791 - 4.092 0.467 - 569.1 1 1 0 -0.0038 23 0 0 0 - - - - - 7.051 1 221125_WJC_METTL3_EV_vs_WT_F04.22460.22460.3 3.67E-08 16/56 K.KEENLADWYSQVITK.S sp|P07814|SYEP_HUMAN 1 1822.9101 0.97 55111 22460 3 1822.908151 608.644 Bifunctional glutamate\proline--tRNA ligase OS=Homo sapiens OX=9606 GN=EPRS1 PE=1 SV=5 4.68 3581.5 - 1.45E+06 - - - -1.0851 - 2.994 0.568 - 289 1 2 0 -0.002 15 0 0 0 3.89E+07 4.01E+07 - - - 7.7335 0.9999 221125_WJC_METTL3_EV_vs_WT_F04.22462.22462.4 1.10E-06 19/102 K.LVINGNPITIFQER[166.11]DPSK[136.11].L sp|P04406|G3P_HUMAN 1 2058.1229 1.52 55113 22462 4 2058.121232 515.538 Glyceraldehyde-3-phosphate dehydrogenase OS=Homo sapiens OX=9606 GN=GAPDH PE=1 SV=3 6.07 3581.8 - 686383 - - - -0.791 - 3.311 0.505 - 297.9 1 2 1 -0.0016 18 0 0 0 2.02E+07 1.33E+07 - - - 4.0312 0.9999 221125_WJC_METTL3_EV_vs_WT_F04.22465.22465.3 9.76E-05 20/68 K.SSGPTSLFAVTVAPPGAR.Q "sp|Q00839|HNRPU_HUMAN,tr|A0A1W2PP35|A0A1W2PP35_HUMAN,tr|A0A1W2PPS1|A0A1W2PPS1_HUMAN,tr|A0A1W2PP22|A0A1W2PP22_HUMAN,tr|A0A1X7SBS1|A0A1X7SBS1_HUMAN" 5 1713.905 0.92 55114 22465 3 1713.903526 572.3089 Heterogeneous nuclear ribonucleoprotein U OS=Homo sapiens OX=9606 GN=HNRNPU PE=1 SV=6 9.47 3582.1 - 2.12E+06 - - - -0.8507 - 2.854 0.409 - 159.2 1 2 0 -0.0015 18 0 0 0 1.02E+08 1.11E+08 - - - 5.711 0.9386 221125_WJC_METTL3_EV_vs_WT_F04.22466.22466.2 0.214 28-Jul R.LTEMETLQSQLMAEK[136.11].L sp|P35579|MYH9_HUMAN 1 1758.8623 0.01 55115 22466 2 1758.851548 880.4384 Myosin-9 OS=Homo sapiens OX=9606 GN=MYH9 PE=1 SV=4 4.25 3582.3 - 1.53E+06 - - - -6.1261 - 1.582 0.267 - 85.5 2 2 0 -0.0108 15 0 0 0 2.92E+05 5.77E+07 - - - 2.0029 1 221125_WJC_METTL3_EV_vs_WT_F04.22469.22469.3 5.49E-07 15/80 R.ETVGDLEAMNEMNDELQENAR[166.11].E "sp|Q14203|DCTN1_HUMAN,tr|A0A804CDA6|A0A804CDA6_HUMAN,tr|E7EX90|E7EX90_HUMAN,tr|A0A7P0Z4C3|A0A7P0Z4C3_HUMAN,tr|Q6AWB1|Q6AWB1_HUMAN" 5 2417.035 2.07 55118 22469 3 2417.029695 806.6856 Dynactin subunit 1 OS=Homo sapiens OX=9606 GN=DCTN1 PE=1 SV=3 3.71 3582.6 - 1.60E+06 - - - -2.211 - 2.865 0.624 - 288.6 1 2 0 -0.0053 21 0 0 0 2.74E+07 1.32E+07 - - - 8.019 0.9999 221125_WJC_METTL3_EV_vs_WT_F04.22470.22470.4 7.34E-06 21/102 K.LVINGNPITIFQERDPSK.L sp|P04406|G3P_HUMAN 1 2040.1004 1.52 55119 22470 4 2040.098614 511.0324 Glyceraldehyde-3-phosphate dehydrogenase OS=Homo sapiens OX=9606 GN=GAPDH PE=1 SV=3 6.07 3582.7 - 1.13E+06 - - - -0.8705 - 3.22 0.51 - 339.1 1 2 1 -0.0018 18 0 0 0 2.02E+07 1.33E+07 - - - 4.0651 0.9973 221125_WJC_METTL3_EV_vs_WT_F04.22471.22471.3 8.13E-06 13/52 Q.AQISALEEQLQQIR.A "sp|P13645|K1C10_HUMAN,tr|A0A1B0GVI3|A0A1B0GVI3_HUMAN" 2 1625.8737 999 55120 22471 3 1625.874415 542.9652 "Keratin, type I cytoskeletal 10 OS=Homo sapiens OX=9606 GN=KRT10 PE=1 SV=6" 4.53 3582.8 - 1.04E+06 - - - 0.4496 - 2.855 0.483 - 267.5 1 1 0 0.0007 14 0 0 0 1.22E+07 0.00E+00 - - - 6.7127 1 221125_WJC_METTL3_EV_vs_WT_F04.22472.22472.2 2.08E-12 19/30 R.TSQEELLAEVVQGQSR.T "sp|Q6PJT7|ZC3HE_HUMAN,tr|G3V256|G3V256_HUMAN,tr|G3V5I6|G3V5I6_HUMAN,tr|H0YJA2|H0YJA2_HUMAN,tr|A0A087WTC9|A0A087WTC9_HUMAN" 5 1772.8905 0.79 55121 22472 2 1772.894208 887.4525 Zinc finger CCCH domain-containing protein 14 OS=Homo sapiens OX=9606 GN=ZC3H14 PE=1 SV=1 4.25 3582.9 - 993892 - - - 2.1158 - 3.678 0.643 - 1113.3 1 2 0 0.0038 16 0 0 0 1.36E+07 1.72E+07 - - - 6.991 0.9995 221125_WJC_METTL3_EV_vs_WT_F04.22478.22478.3 4.54E-08 18/76 R.GEYNVYSTFQSHEPEFDYLK[136.11].S "sp|Q66LE6|2ABD_HUMAN,sp|P63151|2ABA_HUMAN,sp|Q00005|2ABB_HUMAN,tr|H0YB06|H0YB06_HUMAN,tr|E5RIY1|E5RIY1_HUMAN" 5 2460.1001 0.81 55124 22478 3 2460.084581 821.0407 Serine\threonine-protein phosphatase 2A 55 kDa regulatory subunit B delta isoform OS=Homo sapiens OX=9606 GN=PPP2R2D PE=1 SV=1 4.4 3583.7 - 1.30E+06 - - - -6.3172 - 2.956 0.59 - 383.3 1 2 0 -0.0155 20 0 0 0 1.01E+07 1.25E+07 - - - 7.743 0.9999 221125_WJC_METTL3_EV_vs_WT_F04.22479.22479.3 4.90E-08 15/92 K.NGYGFVEFEDSR[166.11]DADDAVYELNGK[136.11].E "sp|Q13247|SRSF6_HUMAN,tr|A0A590UK80|A0A590UK80_HUMAN,tr|A0A590UJK4|A0A590UJK4_HUMAN,tr|A0A590UJP7|A0A590UJP7_HUMAN,tr|A0A590UK01|A0A590UK01_HUMAN" 5 2727.2055 1.25 55125 22479 3 2727.208032 910.0758 Serine\arginine-rich splicing factor 6 OS=Homo sapiens OX=9606 GN=SRSF6 PE=1 SV=2 3.9 3583.8 - 955922 - - - 0.9138 - 2.589 0.574 - 97.1 1 2 1 0.0025 24 0 0 0 1.32E+07 1.06E+07 - - - 7.1483 1 221125_WJC_METTL3_EV_vs_WT_F04.22480.22480.3 9.85E-16 22/108 R.AAAMLPTVGEGYGYGPESELSQASAATR.N sp|Q9BQ04|RBM4B_HUMAN 1 2783.3072 2.13 55126 22480 3 2783.308328 928.7764 RNA-binding protein 4B OS=Homo sapiens OX=9606 GN=RBM4B PE=1 SV=1 4.25 3583.9 - 1.82E+06 - - - 0.3967 - 4.067 0.698 - 204.4 1 2 0 0.0011 28 0 0 0 2.77E+07 1.30E+07 - - - 9.5493 1 221125_WJC_METTL3_EV_vs_WT_F04.22483.22483.2 2.69E-06 18/30 V.INGNPITIFQERDPSK.L sp|P04406|G3P_HUMAN 1 1827.9479 1.7 55127 22483 2 1827.943834 914.9812 Glyceraldehyde-3-phosphate dehydrogenase OS=Homo sapiens OX=9606 GN=GAPDH PE=1 SV=3 6.07 3584.3 - 727672 - - - -2.2309 - 3.506 0.599 - 1296 1 1 1 -0.0041 16 0 0 0 9.82E+06 5.79E+06 - - - 6.5481 1 221125_WJC_METTL3_EV_vs_WT_F04.22486.22486.3 4.61E-13 20/108 R.AAAMLPTVGEGYGYGPESELSQASAATR[166.11].N sp|Q9BQ04|RBM4B_HUMAN 1 2793.3155 2.13 55129 22486 3 2793.313567 932.1124 RNA-binding protein 4B OS=Homo sapiens OX=9606 GN=RBM4B PE=1 SV=1 4.25 3584.7 - 1.36E+06 - - - -0.6899 - 4.008 0.671 - 362.1 1 2 0 -0.0019 28 0 0 0 2.77E+07 1.30E+07 - - - 9.2144 1 221125_WJC_METTL3_EV_vs_WT_F04.22490.22490.3 0.000185 18/48 K.GELTTLIHQLQEK[136.11].D sp|Q86UP2|KTN1_HUMAN 1 1516.8341 1.64 55133 22490 3 1516.835139 506.6186 Kinectin OS=Homo sapiens OX=9606 GN=KTN1 PE=1 SV=1 5.4 3585 - 1.05E+06 - - - 0.7127 - 2.723 0.475 - 384.4 1 2 0 0.0011 13 0 0 0 2.69E+07 1.64E+07 - - - 6.5515 1 221125_WJC_METTL3_EV_vs_WT_F04.22492.22492.2 1.94E-05 15/26 Q.AQISALEEQLQQIR.A "sp|P13645|K1C10_HUMAN,tr|A0A1B0GVI3|A0A1B0GVI3_HUMAN" 2 1625.8737 999 55135 22492 2 1625.870744 813.9441 "Keratin, type I cytoskeletal 10 OS=Homo sapiens OX=9606 GN=KRT10 PE=1 SV=6" 4.53 3585.3 - 542857 - - - -1.8083 - 3.348 0.502 - 700.5 1 1 0 -0.0029 14 0 0 0 1.07E+07 0.00E+00 - - - 5.7802 1 221125_WJC_METTL3_EV_vs_WT_F04.22496.22496.2 7.48E-09 18/40 C.LAISTPDAPATQDGVESLLQK[136.11].F "sp|Q86U44|MTA70_HUMAN,tr|B4E349|B4E349_HUMAN,tr|F5H6D8|F5H6D8_HUMAN,tr|H0YFV6|H0YFV6_HUMAN,tr|B4DTN4|B4DTN4_HUMAN" 5 2161.1358 0 55137 22496 2 2162.133202 1081.5752 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 4.03 3585.8 - 1.63E+06 - - - 461.5272 - 3.335 0.618 - 638.6 1 1 0 0.9974 21 0 0 0 2.93E+05 1.17E+08 - - - 6.2536 0.97 221125_WJC_METTL3_EV_vs_WT_F04.22497.22497.3 6.39E-09 15/76 K.GNPQGFNQGLDC[160.03]DVIVAEVR[166.11].S sp|Q86U44|MTA70_HUMAN 1 2197.0461 1.07 55138 22497 3 2198.032098 733.356 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 4.03 3585.9 - 4.93E+06 - - - 448.7671 - 2.979 0.658 - 237.5 1 2 0 0.986 20 0 0 0 1.65E+07 1.54E+07 - - - 8.2512 1 221125_WJC_METTL3_EV_vs_WT_F04.22498.22498.3 1.47E-06 19/48 K.GELTTLIHQLQEK.D sp|Q86UP2|KTN1_HUMAN 1 1508.8199 1.64 55139 22498 3 1508.821273 503.9472 Kinectin OS=Homo sapiens OX=9606 GN=KTN1 PE=1 SV=1 5.4 3586 - 1.34E+06 - - - 0.9378 - 2.973 0.433 - 613.4 1 2 0 0.0014 13 0 0 0 2.69E+07 1.64E+07 - - - 6.3213 1 221125_WJC_METTL3_EV_vs_WT_F04.22499.22499.3 2.09E-07 14/64 R.SDPDLVAQNIDVVLNRR.S "sp|Q9UBU9|NXF1_HUMAN,tr|B4E227|B4E227_HUMAN,tr|E9PIN3|E9PIN3_HUMAN" 3 1923.0174 1.38 55140 22499 3 1923.019629 642.0131 Nuclear RNA export factor 1 OS=Homo sapiens OX=9606 GN=NXF1 PE=1 SV=1 4.43 3586.1 - 1.27E+06 - - - 1.1654 - 2.395 0.486 - 173.2 1 2 0 0.0022 17 0 0 0 2.05E+07 1.48E+07 - - - 6.1642 1 221125_WJC_METTL3_EV_vs_WT_F04.22504.22504.3 4.04E-11 26/68 R.RPSSLQSLFGLPEAAGAR.D "sp|P39880|CUX1_HUMAN,tr|A0A2R8Y852|A0A2R8Y852_HUMAN,tr|A0A2R8YDI1|A0A2R8YDI1_HUMAN" 3 1855.9904 1.36 55143 22504 3 1855.992981 619.6708 Homeobox protein cut-like 1 OS=Homo sapiens OX=9606 GN=CUX1 PE=1 SV=3 9.6 3586.7 - 1.63E+06 - - - 1.3664 - 3.869 0.583 - 748.8 1 2 0 0.0025 18 0 0 0 1.05E+08 7.78E+07 - - - 8.4083 1 221125_WJC_METTL3_EV_vs_WT_F04.22505.22505.3 1.48E-06 27/68 R.R[166.11]PSSLQSLFGLPEAAGAR[166.11].D "sp|P39880|CUX1_HUMAN,tr|A0A2R8Y852|A0A2R8Y852_HUMAN,tr|A0A2R8YDI1|A0A2R8YDI1_HUMAN" 3 1876.007 1.36 55144 22505 3 1876.008326 626.3429 Homeobox protein cut-like 1 OS=Homo sapiens OX=9606 GN=CUX1 PE=1 SV=3 9.6 3586.8 - 1.79E+06 - - - 0.7148 - 4.174 0.538 - 766.4 1 2 0 0.0013 18 0 0 0 1.06E+08 7.78E+07 - - - 8.0958 0.9115 221125_WJC_METTL3_EV_vs_WT_F04.22506.22506.3 1.1 13/56 K.K[136.11]EENLADWYSQVITK[136.11].S sp|P07814|SYEP_HUMAN 1 1838.9385 0.92 55145 22506 3 1838.945498 613.9868 Bifunctional glutamate\proline--tRNA ligase OS=Homo sapiens OX=9606 GN=EPRS1 PE=1 SV=5 4.68 3587 - 1.44E+06 - - - 3.7897 - 1.819 0.135 - 112 1 2 0 0.007 15 0 0 0 3.71E+07 4.01E+07 - - - 1.6043 1 221125_WJC_METTL3_EV_vs_WT_F04.22508.22508.3 3.28E-06 17/64 K.SLC[160.03]IPFK[136.11]PLC[160.03]ELQPGAK[136.11].C sp|P07814|SYEP_HUMAN 1 1973.0449 0.31 55147 22508 3 1973.047327 658.6889 Bifunctional glutamate\proline--tRNA ligase OS=Homo sapiens OX=9606 GN=EPRS1 PE=1 SV=5 7.78 3587.2 - 1.22E+06 - - - 1.2169 - 3.234 0.535 - 336.1 1 2 0 0.0024 17 0 0 0 7.05E+06 2.26E+07 - - - 7.4692 0.9999 221125_WJC_METTL3_EV_vs_WT_F04.22523.22523.3 5.26E-08 18/60 K.FASFIDKVQFLEQQNK.V sp|P19013|K2C4_HUMAN 1 1940.9996 35.21 55158 22523 3 1941.003423 648.0071 "Keratin, type II cytoskeletal 4 OS=Homo sapiens OX=9606 GN=KRT4 PE=1 SV=5" 6.07 3588.9 - 1.23E+07 - - - 1.9629 - 3.504 0.521 - 416.1 1 2 1 0.0038 16 0 0 0 1.22E+08 3.46E+06 - - - 7.5649 1 221125_WJC_METTL3_EV_vs_WT_F04.22524.22524.4 9.97E-08 25/96 R.EAEAAIYHLQLFEELRR.L "sp|P14618|KPYM_HUMAN,tr|B4DNK4|B4DNK4_HUMAN" 2 2087.08 1.07 55159 22524 4 2087.082103 522.7773 Pyruvate kinase PKM OS=Homo sapiens OX=9606 GN=PKM PE=1 SV=4 4.91 3589 - 2.13E+06 - - - 1.0129 - 3.393 0.575 - 605.6 1 2 0 0.0021 17 0 0 0 1.21E+07 1.12E+07 - - - 4.6544 1 221125_WJC_METTL3_EV_vs_WT_F04.22529.22529.3 8.09E-09 19/80 K.ELSSTEAQLHDAQELLQEETR[166.11].A "sp|Q7Z406|MYH14_HUMAN,tr|A0A0C4DFM8|A0A0C4DFM8_HUMAN" 2 2436.1644 1.52 55164 22529 3 2436.16967 813.0621 Myosin-14 OS=Homo sapiens OX=9606 GN=MYH14 PE=1 SV=2 4.14 3589.7 - 590117 - - - 2.1645 - 3.5 0.606 - 347 1 2 0 0.0053 21 0 0 0 7.10E+06 4.67E+06 - - - 8.2983 1 221125_WJC_METTL3_EV_vs_WT_F04.22534.22534.3 3.47E-06 18/68 K.EQLAQAMFDHIPVGVGSK.G sp|Q9Y3I0|RTCB_HUMAN 1 1925.9669 1.24 55167 22534 3 1925.964799 642.9963 RNA-splicing ligase RtcB homolog OS=Homo sapiens OX=9606 GN=RTCB PE=1 SV=1 5.32 3590.2 - 1.94E+06 - - - -1.108 - 3.264 0.577 - 319.2 1 2 0 -0.0021 18 0 0 0 4.40E+07 3.55E+07 - - - 7.9181 1 221125_WJC_METTL3_EV_vs_WT_F04.22539.22539.3 3.23E-08 17/100 K.AGADIELGC[160.03]STPLMEASQEGHLELVK[136.11].Y "sp|Q8IWZ3|ANKH1_HUMAN,tr|E9PDP5|E9PDP5_HUMAN,tr|H3BLS9|H3BLS9_HUMAN" 3 2762.3346 0.94 55172 22539 3 2762.335046 921.7855 Ankyrin repeat and KH domain-containing protein 1 OS=Homo sapiens OX=9606 GN=ANKHD1 PE=1 SV=1 4.25 3590.8 - 956163 - - - 0.1499 - 3.058 0.549 - 226.2 1 2 0 0.0004 26 0 0 0 1.03E+07 1.09E+07 - - - 7.2323 0.9999 221125_WJC_METTL3_EV_vs_WT_F04.22546.22546.2 9.23E-07 13/22 K.NIEDVIAQGIGK[136.11].L "sp|P05387|RLA2_HUMAN,tr|H0YDD8|H0YDD8_HUMAN" 2 1263.6914 1.22 55177 22546 2 1263.691688 632.853 60S acidic ribosomal protein P2 OS=Homo sapiens OX=9606 GN=RPLP2 PE=1 SV=1 4.37 3591.7 - 994229 - - - 0.2152 - 2.439 0.473 - 385.1 1 2 0 0.0003 12 0 0 0 3.83E+07 3.14E+07 - - - 4.8804 0.9997 221125_WJC_METTL3_EV_vs_WT_F04.22553.22553.3 2.31E-07 15/72 K.QETEVELYNEFPEPIKLDK.N "sp|P51149|RAB7A_HUMAN,tr|C9J4V0|C9J4V0_HUMAN,tr|C9J7D1|C9J7D1_HUMAN,tr|C9J8S3|C9J8S3_HUMAN,tr|C9J4S4|C9J4S4_HUMAN,tr|A0A6Q8PGE6|A0A6Q8PGE6_HUMAN" 6 2320.1475 4.09 55182 22553 3 2320.14206 774.3898 Ras-related protein Rab-7a OS=Homo sapiens OX=9606 GN=RAB7A PE=1 SV=1 4.14 3592.6 - 1.90E+06 - - - -2.327 - 2.711 0.506 - 200.9 1 2 1 -0.0054 19 0 0 0 2.61E+07 6.39E+06 - - - 6.6301 1 221125_WJC_METTL3_EV_vs_WT_F04.22554.22554.3 1.33E-10 16/84 K.NEFVSLINC[160.03]SSQPPLISHGIGK.D "sp|O95793|STAU1_HUMAN,tr|Q5JW30|Q5JW30_HUMAN" 2 2396.2158 2.45 55183 22554 3 2396.214616 799.7459 Double-stranded RNA-binding protein Staufen homolog 1 OS=Homo sapiens OX=9606 GN=STAU1 PE=1 SV=2 6.74 3592.7 - 1.01E+06 - - - -0.507 - 3.349 0.565 - 203.3 1 2 0 -0.0012 22 0 0 0 3.44E+07 1.40E+07 - - - 7.7044 0.9999 221125_WJC_METTL3_EV_vs_WT_F04.22562.22562.2 3.97E-07 15/22 K.NIEDVIAQGIGK.L "sp|P05387|RLA2_HUMAN,tr|H0YDD8|H0YDD8_HUMAN" 2 1255.6772 1.22 55189 22562 2 1255.678993 628.8459 60S acidic ribosomal protein P2 OS=Homo sapiens OX=9606 GN=RPLP2 PE=1 SV=1 4.37 3593.8 - 3.34E+06 - - - 1.4152 - 2.531 0.54 - 557.8 1 2 0 0.0018 12 0 0 0 3.83E+07 3.14E+07 - - - 5.4722 1 221125_WJC_METTL3_EV_vs_WT_F04.22564.22564.3 2.60E-09 21/68 K.EQLAQAMFDHIPVGVGSK[136.11].G sp|Q9Y3I0|RTCB_HUMAN 1 1933.9811 1.24 55191 22564 3 1933.983138 645.6677 RNA-splicing ligase RtcB homolog OS=Homo sapiens OX=9606 GN=RTCB PE=1 SV=1 5.32 3593.9 - 3.31E+06 - - - 1.0367 - 3.145 0.598 - 454 1 2 0 0.002 18 0 0 0 4.40E+07 3.55E+07 - - - 8.0597 1 221125_WJC_METTL3_EV_vs_WT_F04.22565.22565.3 1.40E-18 30/96 K.EQASHLGGAVFSGAGNIAAATGLVK[136.11].R "sp|Q16143|SYUB_HUMAN,tr|G4Y816|G4Y816_HUMAN" 2 2333.2219 1.57 55192 22565 3 2333.226045 778.7479 Beta-synuclein OS=Homo sapiens OX=9606 GN=SNCB PE=1 SV=1 6.85 3594 - 2.70E+06 - - - 1.7727 - 5.233 0.726 - 810.5 1 2 0 0.0041 25 0 0 0 8.80E+07 5.60E+07 - - - 10.4406 0.7971 221125_WJC_METTL3_EV_vs_WT_F04.22567.22567.3 0.0325 Sep-92 K.TPSTMENDSSNLDPSQAPSLAQPL.V "sp|Q14157|UBP2L_HUMAN,tr|F8W726|F8W726_HUMAN,tr|Q5VU77|Q5VU77_HUMAN" 3 2499.1435 - 55194 22567 3 2499.14967 834.0551 Ubiquitin-associated protein 2-like OS=Homo sapiens OX=9606 GN=UBAP2L PE=1 SV=2 3.49 3594.3 - 780727 - - - 2.4636 - 1.452 0.356 - 32 1 1 0 0.0062 24 0 0 0 - - - - - 3.3735 1 221125_WJC_METTL3_EV_vs_WT_F04.22568.22568.3 7.11E-16 28/108 R.HLLPNSGAAATSAAMAAAAATTSSYYGR[166.11].D sp|Q9BQ04|RBM4B_HUMAN 1 2691.295 1.58 55195 22568 3 2691.300456 898.1056 RNA-binding protein 4B OS=Homo sapiens OX=9606 GN=RBM4B PE=1 SV=1 8.6 3594.4 - 759950 - - - 2.0146 - 5.715 0.715 - 1103.9 1 2 0 0.0054 28 0 0 0 6.64E+07 4.21E+07 - - - 10.5203 1 221125_WJC_METTL3_EV_vs_WT_F04.22569.22569.3 7.19E-09 21/68 R.C[160.03]HVPLAQAQALVTSELEK.F "sp|Q96C01|F136A_HUMAN,tr|E7EQY1|E7EQY1_HUMAN,tr|C9JF51|C9JF51_HUMAN" 3 1993.0303 4.75 55196 22569 3 1993.032362 665.3507 Protein FAM136A OS=Homo sapiens OX=9606 GN=FAM136A PE=1 SV=1 5.4 3594.5 - 727178 - - - 1.0537 - 4.52 0.606 - 745 1 2 0 0.0021 18 0 0 0 2.18E+07 4.58E+06 - - - 9.0521 1 221125_WJC_METTL3_EV_vs_WT_F04.22572.22572.3 6.44E-09 14/60 K.TC[160.03]FVDC[160.03]LIEQTHPEIR[166.11].K sp|Q15029|U5S1_HUMAN 1 2026.948 2 55199 22572 3 2026.946534 676.6566 116 kDa U5 small nuclear ribonucleoprotein component OS=Homo sapiens OX=9606 GN=EFTUD2 PE=1 SV=1 4.65 3594.9 - 526140 - - - -0.7242 - 2.813 0.65 - 302.8 1 2 0 -0.0015 16 0 0 0 9.51E+06 4.77E+06 - - - 8.4402 1 221125_WJC_METTL3_EV_vs_WT_F04.22575.22575.2 7.03E-11 21/30 K.K[136.11]VSQEILELLNTTTAK[136.11].E "sp|Q86U44|MTA70_HUMAN,tr|H0YFV6|H0YFV6_HUMAN" 2 1803.0324 0.001 55202 22575 2 1803.036302 902.5235 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 6.14 3595.3 - 494383 - - - 2.1475 - 4.175 0.674 - 1275.4 1 2 0 0.0039 16 0 0 0 0.00E+00 5.77E+06 - - - 7.5315 1 221125_WJC_METTL3_EV_vs_WT_F04.22582.22582.3 9.22E-08 21/52 K.SLNNQFASFIDKVR.F sp|P04264|K2C1_HUMAN 1 1637.8526 999 55207 22582 3 1637.856546 546.9581 "Keratin, type II cytoskeletal 1 OS=Homo sapiens OX=9606 GN=KRT1 PE=1 SV=6" 8.46 3596.1 - 2.85E+06 - - - 2.4367 - 3.468 0.642 - 508.5 1 2 1 0.004 14 0 0 0 2.42E+08 0.00E+00 - - - 9.0014 1 221125_WJC_METTL3_EV_vs_WT_F04.22583.22583.3 1.11E-20 34/108 R.HLLPNSGAAATSAAMAAAAATTSSYYGR.D sp|Q9BQ04|RBM4B_HUMAN 1 2681.2868 1.58 55208 22583 3 2681.291163 894.7695 RNA-binding protein 4B OS=Homo sapiens OX=9606 GN=RBM4B PE=1 SV=1 8.6 3596.2 - 2.22E+06 - - - 1.6406 - 6.615 0.773 - 1476.1 1 2 0 0.0044 28 0 0 0 6.64E+07 4.21E+07 - - - 11.5037 1 221125_WJC_METTL3_EV_vs_WT_F04.22584.22584.3 4.31E-14 20/84 K.NEFVSLINC[160.03]SSQPPLISHGIGK[136.11].D "sp|O95793|STAU1_HUMAN,tr|Q5JW30|Q5JW30_HUMAN" 2 2404.23 2.68 55209 22584 3 2404.234058 802.4173 Double-stranded RNA-binding protein Staufen homolog 1 OS=Homo sapiens OX=9606 GN=STAU1 PE=1 SV=2 6.74 3596.2 - 1.75E+06 - - - 1.675 - 3.601 0.72 - 341.5 1 2 0 0.004 22 0 0 0 3.76E+07 1.40E+07 - - - 9.6037 1 221125_WJC_METTL3_EV_vs_WT_F04.22586.22586.3 1.51E-09 19/60 K.TC[160.03]FVDC[160.03]LIEQTHPEIR.K sp|Q15029|U5S1_HUMAN 1 2016.9397 2 55211 22586 3 2016.944209 673.3205 116 kDa U5 small nuclear ribonucleoprotein component OS=Homo sapiens OX=9606 GN=EFTUD2 PE=1 SV=1 4.65 3596.5 - 1.13E+06 - - - 2.2197 - 3.54 0.654 - 631.1 1 2 0 0.0045 16 0 0 0 9.51E+06 4.77E+06 - - - 9.0738 1 221125_WJC_METTL3_EV_vs_WT_F04.22587.22587.4 1.71E-06 24/132 R.GFGFVTYSC[160.03]VEEVDAAMC[160.03]ARPHK.V "sp|P51991|ROA3_HUMAN,tr|A0A7I2V5D8|A0A7I2V5D8_HUMAN,tr|A0A7I2V2R3|A0A7I2V2R3_HUMAN,tr|A0A7I2V4J6|A0A7I2V4J6_HUMAN,tr|A0A7I2V4G0|A0A7I2V4G0_HUMAN,tr|A0A7I2V402|A0A7I2V402_HUMAN" 6 2630.1716 1.47 55212 22587 4 2630.173755 658.5502 Heterogeneous nuclear ribonucleoprotein A3 OS=Homo sapiens OX=9606 GN=HNRNPA3 PE=1 SV=2 5.44 3596.6 - 832878 - - - 0.8193 - 4.501 0.579 - 483.2 1 2 0 0.0022 23 0 0 0 4.67E+07 3.18E+07 - - - 4.7524 1 221125_WJC_METTL3_EV_vs_WT_F04.22588.22588.3 7.17E-08 17/80 K.LSIFDANESGFESYEALPQHK.L "sp|P26358|DNMT1_HUMAN,tr|A0A7I2V5D0|A0A7I2V5D0_HUMAN,tr|A0A7I2V5F1|A0A7I2V5F1_HUMAN,tr|A0A7I2V5F6|A0A7I2V5F6_HUMAN,tr|A0A7I2YQA8|A0A7I2YQA8_HUMAN,tr|A0A7I2YQQ0|A0A7I2YQQ0_HUMAN,tr|A0A7I2V311|A0A7I2V311_HUMAN,tr|A0A7I2V490|A0A7I2V490_HUMAN" 8 2381.1176 0.44 55213 22588 3 2381.131721 794.7131 DNA (cytosine-5)-methyltransferase 1 OS=Homo sapiens OX=9606 GN=DNMT1 PE=1 SV=2 4.4 3596.8 - 704917 - - - 5.9489 - 3.503 0.625 - 246.8 1 2 0 0.0142 21 0 0 0 4.45E+06 1.02E+07 - - - 8.5097 0.9992 221125_WJC_METTL3_EV_vs_WT_F04.22589.22589.3 1.53E-05 Dec-60 R.QAQIEVVPSASALIIK.A sp|P30050|RL12_HUMAN 1 1665.9665 1.63 55214 22589 3 1665.975254 556.3295 60S ribosomal protein L12 OS=Homo sapiens OX=9606 GN=RPL12 PE=1 SV=1 6 3596.9 - 544266 - - - 5.2414 - 2.403 0.476 - 222.6 1 2 0 0.0087 16 0 0 0 2.95E+06 1.81E+06 - - - 6.094 0.9405 221125_WJC_METTL3_EV_vs_WT_F04.22594.22594.3 0.432 Jun-44 K.NIEDVIAQGIGK[136.11].L "sp|P05387|RLA2_HUMAN,tr|H0YDD8|H0YDD8_HUMAN" 2 1263.6914 0.96 55219 22594 3 1263.693248 422.2377 60S acidic ribosomal protein P2 OS=Homo sapiens OX=9606 GN=RPLP2 PE=1 SV=1 4.37 3597.5 - 137602 - - - 1.4497 - 1.259 0.158 - 62 1 2 0 0.0018 12 0 0 0 1.43E+06 1.48E+06 - - - 0.9394 1 221125_WJC_METTL3_EV_vs_WT_F04.22598.22598.3 1.83E-13 21/92 K.IGEEQSPEDAEDGPPELLFIHGGH.T "sp|Q09028|RBBP4_HUMAN,tr|H0YCT5|H0YCT5_HUMAN,tr|H0YDK2|H0YDK2_HUMAN,tr|H0YEU5|H0YEU5_HUMAN,tr|H0YF10|H0YF10_HUMAN" 5 2572.1718 - 55221 22598 3 2572.174341 858.3979 Histone-binding protein RBBP4 OS=Homo sapiens OX=9606 GN=RBBP4 PE=1 SV=3 4 3598.1 - 990103 - - - 0.9968 - 3.848 0.622 - 486.5 1 1 0 0.0026 24 0 0 0 - - - - - 8.6038 0.9999 221125_WJC_METTL3_EV_vs_WT_F04.22599.22599.3 3.08E-08 17/68 R.DESSPYAAMLAAQDVAQR.C "sp|P62263|RS14_HUMAN,tr|A0A2R8Y811|A0A2R8Y811_HUMAN,tr|E5RH77|E5RH77_HUMAN" 3 1921.884 1.42 55222 22599 3 1921.891992 641.6353 40S ribosomal protein S14 OS=Homo sapiens OX=9606 GN=RPS14 PE=1 SV=3 4.03 3598.2 - 1.20E+06 - - - 4.1631 - 3.136 0.596 - 450.9 1 2 0 0.008 18 0 0 0 1.01E+07 7.12E+06 - - - 8.0287 1 221125_WJC_METTL3_EV_vs_WT_F04.22600.22600.4 1.04E-06 24/132 R.GFGFVTYSC[160.03]VEEVDAAMC[160.03]AR[166.11]PHK[136.11].V "sp|P51991|ROA3_HUMAN,tr|A0A7I2V5D8|A0A7I2V5D8_HUMAN,tr|A0A7I2V2R3|A0A7I2V2R3_HUMAN,tr|A0A7I2V4J6|A0A7I2V4J6_HUMAN,tr|A0A7I2V4G0|A0A7I2V4G0_HUMAN,tr|A0A7I2V402|A0A7I2V402_HUMAN" 6 2648.1941 1.47 55223 22600 4 2648.201171 663.0558 Heterogeneous nuclear ribonucleoprotein A3 OS=Homo sapiens OX=9606 GN=HNRNPA3 PE=1 SV=2 5.44 3598.3 - 997657 - - - 2.6815 - 4.011 0.597 - 426.6 1 2 0 0.0071 23 0 0 0 4.67E+07 3.18E+07 - - - 4.8704 1 221125_WJC_METTL3_EV_vs_WT_F04.22601.22601.3 7.15E-10 17/68 R.GTEDITSPHGIPLDLLDR[166.11].V "sp|Q9Y265|RUVB1_HUMAN,tr|E7ETR0|E7ETR0_HUMAN,tr|H7C4G5|H7C4G5_HUMAN,tr|J3QLR1|J3QLR1_HUMAN" 4 1957.9984 1.14 55224 22601 3 1958.002675 653.6734 RuvB-like 1 OS=Homo sapiens OX=9606 GN=RUVBL1 PE=1 SV=1 4.22 3598.4 - 859216 - - - 2.1624 - 3.581 0.599 - 302.1 1 2 0 0.0042 18 0 0 0 1.76E+07 1.55E+07 - - - 8.3936 1 221125_WJC_METTL3_EV_vs_WT_F04.22602.22602.3 3.59E-12 19/68 R.DESSPYAAMLAAQDVAQR[166.11].C "sp|P62263|RS14_HUMAN,tr|A0A2R8Y811|A0A2R8Y811_HUMAN,tr|E5RH77|E5RH77_HUMAN" 3 1931.8923 1.42 55225 22602 3 1931.89835 644.9714 40S ribosomal protein S14 OS=Homo sapiens OX=9606 GN=RPS14 PE=1 SV=3 4.03 3598.6 - 791034 - - - 3.1518 - 3.628 0.653 - 575.5 1 2 0 0.0061 18 0 0 0 1.01E+07 7.12E+06 - - - 9.0276 0.9999 221125_WJC_METTL3_EV_vs_WT_F04.22603.22603.3 1.70E-07 18/80 R.STQAPLIIR[166.11]PDSGNPLDTVLK[136.11].V "sp|P43490|NAMPT_HUMAN,tr|A0A7P0T862|A0A7P0T862_HUMAN,tr|B7Z8W6|B7Z8W6_HUMAN,tr|A0A7P0T931|A0A7P0T931_HUMAN,tr|A0A7P0T8L3|A0A7P0T8L3_HUMAN,tr|A0A7P0T973|A0A7P0T973_HUMAN,tr|A0A7P0T895|A0A7P0T895_HUMAN,tr|A0A0C4DFS8|A0A0C4DFS8_HUMAN,tr|A0A7P0TAS5|A0A7P0TAS5_HUMAN,tr|A0A7P0T9I9|A0A7P0T9I9_HUMAN,tr|A0A7P0T8D2|A0A7P0T8D2_HUMAN" 11 2252.2495 1.66 55226 22603 3 2252.253207 751.7571 Nicotinamide phosphoribosyltransferase OS=Homo sapiens OX=9606 GN=NAMPT PE=1 SV=1 5.68 3598.7 - 743410 - - - 1.6384 - 3.448 0.432 - 353.4 1 2 0 0.0037 21 0 0 0 1.22E+07 7.37E+06 - - - 6.3229 0.9996 221125_WJC_METTL3_EV_vs_WT_F04.22613.22613.3 1.61E-06 Dec-68 K.LVINGNPITIFQERDPSK.L sp|P04406|G3P_HUMAN 1 2040.1004 1.21 55235 22613 3 2040.105819 681.0407 Glyceraldehyde-3-phosphate dehydrogenase OS=Homo sapiens OX=9606 GN=GAPDH PE=1 SV=3 6.07 3600 - 276260 - - - 2.6611 - 2.489 0.521 - 128.3 1 2 1 0.0054 18 0 0 0 5.06E+06 4.17E+06 - - - 6.6178 1 221125_WJC_METTL3_EV_vs_WT_F04.22616.22616.3 6.50E-12 18/84 K.DQLQTFSEEHPVLLTEAPLNPR[166.11].K "sp|P61163|ACTZ_HUMAN,tr|R4GMT0|R4GMT0_HUMAN,tr|A0A1B0GVS3|A0A1B0GVS3_HUMAN" 3 2543.2895 0.87 55238 22616 3 2543.289689 848.7705 Alpha-centractin OS=Homo sapiens OX=9606 GN=ACTR1A PE=1 SV=1 4.4 3600.2 - 1.29E+06 - - - 0.0598 - 3.537 0.632 - 248.7 1 2 0 0.0002 22 0 0 0 7.71E+07 8.82E+07 - - - 8.5812 1 221125_WJC_METTL3_EV_vs_WT_F04.22617.22617.3 8.81E-07 14/60 K.GLDVDSLVIEHIQVNK[136.11].A "sp|P18621|RL17_HUMAN,tr|A0A087WWH0|A0A087WWH0_HUMAN,tr|J3QS96|J3QS96_HUMAN,tr|J3QLC8|J3QLC8_HUMAN,tr|J3QQT2|J3QQT2_HUMAN,tr|A0A0A0MRF8|A0A0A0MRF8_HUMAN,tr|J3KRB3|J3KRB3_HUMAN,tr|J3KRX5|J3KRX5_HUMAN,tr|A0A087WXM6|A0A087WXM6_HUMAN,tr|A0A0A6YYL6|A0A0A6YYL6_HUMAN" 10 1785.9716 1.02 55239 22617 3 1785.973305 596.3311 60S ribosomal protein L17 OS=Homo sapiens OX=9606 GN=RPL17 PE=1 SV=3 4.54 3600.3 - 966406 - - - 0.9468 - 2.615 0.475 - 157.1 1 2 0 0.0017 16 0 0 0 3.44E+07 3.36E+07 - - - 6.3018 0.9999 221125_WJC_METTL3_EV_vs_WT_F04.22618.22618.3 3.58E-06 13/80 R.STQAPLIIRPDSGNPLDTVLK.V "sp|P43490|NAMPT_HUMAN,tr|A0A7P0T862|A0A7P0T862_HUMAN,tr|B7Z8W6|B7Z8W6_HUMAN,tr|A0A7P0T931|A0A7P0T931_HUMAN,tr|A0A7P0T8L3|A0A7P0T8L3_HUMAN,tr|A0A7P0T973|A0A7P0T973_HUMAN,tr|A0A7P0T895|A0A7P0T895_HUMAN,tr|A0A0C4DFS8|A0A0C4DFS8_HUMAN,tr|A0A7P0TAS5|A0A7P0TAS5_HUMAN,tr|A0A7P0T9I9|A0A7P0T9I9_HUMAN,tr|A0A7P0T8D2|A0A7P0T8D2_HUMAN" 11 2234.227 1.66 55240 22618 3 2234.231218 745.7496 Nicotinamide phosphoribosyltransferase OS=Homo sapiens OX=9606 GN=NAMPT PE=1 SV=1 5.68 3600.4 - 897804 - - - 1.8669 - 2.834 0.448 - 133.1 1 2 0 0.0042 21 0 0 0 1.22E+07 7.37E+06 - - - 6.031 1 221125_WJC_METTL3_EV_vs_WT_F04.22620.22620.3 3.60E-09 18/60 K.GLDVDSLVIEHIQVNK.A "sp|P18621|RL17_HUMAN,tr|A0A087WWH0|A0A087WWH0_HUMAN,tr|J3QS96|J3QS96_HUMAN,tr|J3QLC8|J3QLC8_HUMAN,tr|J3QQT2|J3QQT2_HUMAN,tr|A0A0A0MRF8|A0A0A0MRF8_HUMAN,tr|J3KRB3|J3KRB3_HUMAN,tr|J3KRX5|J3KRX5_HUMAN,tr|A0A087WXM6|A0A087WXM6_HUMAN,tr|A0A0A6YYL6|A0A0A6YYL6_HUMAN" 10 1777.9574 1.02 55242 22620 3 1777.961208 593.6597 60S ribosomal protein L17 OS=Homo sapiens OX=9606 GN=RPL17 PE=1 SV=3 4.54 3600.6 - 727275 - - - 2.1339 - 3.383 0.573 - 284.7 1 2 0 0.0038 16 0 0 0 3.44E+07 3.36E+07 - - - 8.0545 1 221125_WJC_METTL3_EV_vs_WT_F04.22622.22622.3 7.99E-08 18/68 K.HTAMVSWGGVSIPNSPFR.V "sp|P21333|FLNA_HUMAN,tr|A0A7P0NMY4|A0A7P0NMY4_HUMAN,tr|Q60FE5|Q60FE5_HUMAN" 3 1941.952 0.64 55244 22622 3 1941.953633 648.3246 Filamin-A OS=Homo sapiens OX=9606 GN=FLNA PE=1 SV=4 9.76 3600.9 - 554615 - - - 0.8661 - 3.622 0.57 - 285.4 1 2 0 0.0017 18 0 0 0 8.52E+06 1.33E+07 - - - 8.0993 1 221125_WJC_METTL3_EV_vs_WT_F04.22624.22624.3 0.00191 14/60 K.K[136.11]VSQEILELLNTTTAK[136.11].E "sp|Q86U44|MTA70_HUMAN,tr|H0YFV6|H0YFV6_HUMAN" 2 1803.0324 0 55245 22624 3 1803.034624 602.0181 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 6.14 3601.2 - 1.47E+06 - - - 1.2168 - 3.209 0.606 - 356.9 1 2 0 0.0022 16 0 0 0 7.93E+04 8.43E+07 - - - 8.2874 1 221125_WJC_METTL3_EV_vs_WT_F04.22626.22626.3 0.000103 20/76 R.HVDLLEVAQETDGFSGSDLK[136.11].E sp|Q8NBU5|ATAD1_HUMAN 1 2167.0524 0.82 55246 22626 3 2167.046993 723.3581 Outer mitochondrial transmembrane helix translocase OS=Homo sapiens OX=9606 GN=ATAD1 PE=1 SV=1 4.1 3601.4 - 868958 - - - -2.5149 - 3.728 0.541 - 520.5 1 2 0 -0.0054 20 0 0 0 5.45E+06 6.62E+06 - - - 7.7624 1 221125_WJC_METTL3_EV_vs_WT_F04.22627.22627.3 2.08E-11 21/92 R.LDGGTDITFPDGDQELDLGSAGGR.F "sp|Q86U06|RBM23_HUMAN,tr|H0YJJ3|H0YJJ3_HUMAN,tr|G3XAP0|G3XAP0_HUMAN,tr|G3V5Z6|G3V5Z6_HUMAN" 4 2405.0983 1.72 55247 22627 3 2405.101014 802.7067 Probable RNA-binding protein 23 OS=Homo sapiens OX=9606 GN=RBM23 PE=1 SV=1 3.61 3601.5 - 490868 - - - 1.138 - 3.474 0.679 - 423.1 1 2 0 0.0027 24 0 0 0 6.66E+07 3.88E+07 - - - 9.0018 0.9988 221125_WJC_METTL3_EV_vs_WT_F04.22632.22632.3 0.0227 13/64 R.AAVEEGIVLGGGC[160.03]ALLR[166.11].C "sp|P10809|CH60_HUMAN,tr|A0A7I2V2X6|A0A7I2V2X6_HUMAN,tr|A0A7I2YQK6|A0A7I2YQK6_HUMAN,tr|A0A7I2V599|A0A7I2V599_HUMAN" 4 1693.9061 1.39 55252 22632 3 1693.908643 565.6426 "60 kDa heat shock protein, mitochondrial OS=Homo sapiens OX=9606 GN=HSPD1 PE=1 SV=2" 4.53 3602.2 - 253723 - - - 1.5243 - 2.137 0.27 - 153.7 1 2 0 0.0026 17 0 0 0 6.44E+06 4.64E+06 - - - 3.468 0.8432 221125_WJC_METTL3_EV_vs_WT_F04.22633.22633.3 4.12E-08 14/72 F.EAHPNDLYVEGLPENIPFR[166.11].S "sp|P78347|GTF2I_HUMAN,tr|A0A494C0Q7|A0A494C0Q7_HUMAN,tr|A0A494C1K3|A0A494C1K3_HUMAN" 3 2219.0887 6.29 55253 22633 3 2219.103593 740.7035 General transcription factor II-I OS=Homo sapiens OX=9606 GN=GTF2I PE=1 SV=2 4.4 3602.3 - 200441 - - - 6.7325 - 2.742 0.476 - 165.9 1 1 0 0.0149 19 0 0 0 1.45E+07 2.31E+06 - - - 6.3209 1 221125_WJC_METTL3_EV_vs_WT_F04.22637.22637.3 5.09E-11 27/108 K.QAQILASEAEKAEQINQAAGEASAVLAK.A "sp|Q9UJZ1|STML2_HUMAN,tr|A0A087WYB4|A0A087WYB4_HUMAN,tr|F2Z2I8|F2Z2I8_HUMAN" 3 2838.4723 1.5 55255 22637 3 2838.478071 947.1647 "Stomatin-like protein 2, mitochondrial OS=Homo sapiens OX=9606 GN=STOML2 PE=1 SV=1" 4.49 3602.9 - 902881 - - - 2.0275 - 5.1 0.607 - 791 1 2 1 0.0058 28 0 0 0 2.12E+07 1.41E+07 - - - 9.0542 0.9999 221125_WJC_METTL3_EV_vs_WT_F04.22639.22639.3 2.15E-08 17/64 R.AAVEEGIVLGGGC[160.03]ALLR.C "sp|P10809|CH60_HUMAN,tr|A0A7I2V2X6|A0A7I2V2X6_HUMAN,tr|A0A7I2YQK6|A0A7I2YQK6_HUMAN,tr|A0A7I2V599|A0A7I2V599_HUMAN" 4 1683.8978 1.37 55257 22639 3 1683.905728 562.3065 "60 kDa heat shock protein, mitochondrial OS=Homo sapiens OX=9606 GN=HSPD1 PE=1 SV=2" 4.53 3603.1 - 538400 - - - 4.7135 - 3.355 0.605 - 355.3 1 2 0 0.0079 17 0 0 0 6.37E+06 4.64E+06 - - - 8.3409 0.9995 221125_WJC_METTL3_EV_vs_WT_F04.22641.22641.4 4.66E-08 17/126 R.THPVEIFYTPEPER[166.11]DYLEAAIR[166.11].T sp|O43143|DHX15_HUMAN 1 2665.3291 1.35 55259 22641 4 2665.338229 667.3396 Pre-mRNA-splicing factor ATP-dependent RNA helicase DHX15 OS=Homo sapiens OX=9606 GN=DHX15 PE=1 SV=2 4.57 3603.4 - 445762 - - - 3.4221 - 3.005 0.505 - 148.3 1 2 1 0.0091 22 0 0 0 8.12E+06 6.03E+06 - - - 3.979 1 221125_WJC_METTL3_EV_vs_WT_F04.22643.22643.2 1.01E-09 17/46 R.LDGGTDITFPDGDQELDLGSAGGR.F "sp|Q86U06|RBM23_HUMAN,tr|H0YJJ3|H0YJJ3_HUMAN,tr|G3XAP0|G3XAP0_HUMAN,tr|G3V5Z6|G3V5Z6_HUMAN" 4 2405.0983 2.06 55261 22643 2 2405.10576 1203.5564 Probable RNA-binding protein 23 OS=Homo sapiens OX=9606 GN=RBM23 PE=1 SV=1 3.61 3603.6 - 204363 - - - 3.1113 - 3.492 0.715 - 401.2 1 2 0 0.0075 24 0 0 0 1.05E+07 5.10E+06 - - - 7.394 1 221125_WJC_METTL3_EV_vs_WT_F04.22648.22648.3 4.39E-12 20/84 K.DQLQTFSEEHPVLLTEAPLNPR.K "sp|P61163|ACTZ_HUMAN,tr|R4GMT0|R4GMT0_HUMAN,tr|A0A1B0GVS3|A0A1B0GVS3_HUMAN" 3 2533.2813 0.9 55264 22648 3 2533.2849 845.4344 Alpha-centractin OS=Homo sapiens OX=9606 GN=ACTR1A PE=1 SV=1 4.4 3604.2 - 4.19E+06 - - - 1.4341 - 3.601 0.601 - 294.7 1 2 0 0.0036 22 0 0 0 7.71E+07 8.58E+07 - - - 8.2771 0.9978 221125_WJC_METTL3_EV_vs_WT_F04.22649.22649.3 0.0183 16/68 K.HTAMVSWGGVSIPNSPFR[166.11].V "sp|P21333|FLNA_HUMAN,tr|A0A7P0NMY4|A0A7P0NMY4_HUMAN,tr|Q60FE5|Q60FE5_HUMAN" 3 1951.9602 0.69 55265 22649 3 1951.961329 651.6607 Filamin-A OS=Homo sapiens OX=9606 GN=FLNA PE=1 SV=4 9.76 3604.4 - 800427 - - - 0.5676 - 2.786 0.15 - 182.8 1 2 0 0.0011 18 0 0 0 8.52E+06 1.24E+07 - - - 2.7634 0.9995 221125_WJC_METTL3_EV_vs_WT_F04.22651.22651.4 3.11E-09 20/162 K.QAQILASEAEKAEQINQAAGEASAVLAK.A "sp|Q9UJZ1|STML2_HUMAN,tr|A0A087WYB4|A0A087WYB4_HUMAN,tr|F2Z2I8|F2Z2I8_HUMAN" 3 2838.4723 1.88 55267 22651 4 2838.478993 710.6254 "Stomatin-like protein 2, mitochondrial OS=Homo sapiens OX=9606 GN=STOML2 PE=1 SV=1" 4.49 3604.6 - 598150 - - - 2.3523 - 3.869 0.442 - 225.2 1 2 1 0.0067 28 0 0 0 6.10E+06 3.24E+06 - - - 3.4914 0.9993 221125_WJC_METTL3_EV_vs_WT_F04.22652.22652.3 2.30E-07 14/68 K.DKVTLVVGASQDIIPQLK.K "sp|P21964|COMT_HUMAN,tr|E7EUU8|E7EUU8_HUMAN,tr|E7EMS6|E7EMS6_HUMAN,tr|H7BZ45|H7BZ45_HUMAN,tr|A0A7I2V3G7|A0A7I2V3G7_HUMAN,tr|A0A7I2V370|A0A7I2V370_HUMAN" 6 1923.1041 1.38 55268 22652 3 1923.109306 642.042 Catechol O-methyltransferase OS=Homo sapiens OX=9606 GN=COMT PE=1 SV=2 5.96 3604.7 - 369110 - - - 2.7185 - 2.556 0.449 - 166.2 1 2 1 0.0052 18 0 0 0 1.32E+07 9.56E+06 - - - 5.8813 0.9927 221125_WJC_METTL3_EV_vs_WT_F04.22655.22655.3 3.50E-06 21/96 K.IDSIPHLNNSTPLVDPSVYGYGVQK.R sp|Q96I24|FUBP3_HUMAN 1 2712.3759 -1 55270 22655 3 2713.366552 905.1326 Far upstream element-binding protein 3 OS=Homo sapiens OX=9606 GN=FUBP3 PE=1 SV=2 5.21 3605.1 - 2.17E+06 - - - 365.2355 - 3.401 0.536 - 391.5 1 2 0 0.9907 25 0 0 0 0.00E+00 0.00E+00 - - - 7.0576 1 221125_WJC_METTL3_EV_vs_WT_F04.22661.22661.2 5.31E-09 19/36 K.IIAATIENAQPILQIDNAR.L sp|P08779|K1C16_HUMAN 1 2063.1375 999 55275 22661 2 2063.144275 1032.576 "Keratin, type I cytoskeletal 16 OS=Homo sapiens OX=9606 GN=KRT16 PE=1 SV=4" 4.37 3605.9 - 419320 - - - 3.2819 - 4.016 0.652 - 842 1 2 0 0.0068 19 0 0 0 1.19E+07 0.00E+00 - - - 7.2726 0.999 221125_WJC_METTL3_EV_vs_WT_F04.22662.22662.4 5.82E-05 14/150 K.LGGSPTSLGTWGSWIGPDHDKFSAMK.Y "sp|P14314|GLU2B_HUMAN,tr|K7ELL7|K7ELL7_HUMAN,tr|A0A0C4DGP4|A0A0C4DGP4_HUMAN" 3 2731.3064 0.75 55276 22662 4 2731.316211 683.8339 Glucosidase 2 subunit beta OS=Homo sapiens OX=9606 GN=PRKCSH PE=1 SV=2 6.75 3606.1 - 327722 - - - 3.5789 - 2.344 0.469 - 61.3 1 2 1 0.0098 26 0 0 0 1.58E+06 2.10E+06 - - - 3.5742 0.9278 221125_WJC_METTL3_EV_vs_WT_F04.22663.22663.4 0.00247 Sep-96 R.SPSELFAQHIVTIVHHV.K "sp|Q9Y2W1|TR150_HUMAN,tr|A0A3B3ITZ9|A0A3B3ITZ9_HUMAN" 2 1913.0159 - 55277 22663 4 1913.020066 479.2613 Thyroid hormone receptor-associated protein 3 OS=Homo sapiens OX=9606 GN=THRAP3 PE=1 SV=2 6.2 3606.2 - 229759 - - - 2.161 - 1.829 0.352 - 65.8 1 1 0 0.0041 17 0 0 0 - - - - - 2.4983 0.9997 221125_WJC_METTL3_EV_vs_WT_F04.22664.22664.4 6.75E-06 11/114 K.FK[136.11]IEANAGQLYLTGVVVLHK[136.11].D sp|O43395|PRPF3_HUMAN 1 2215.27 3.17 55278 22664 4 2215.274345 554.8248 U4\U6 small nuclear ribonucleoprotein Prp3 OS=Homo sapiens OX=9606 GN=PRPF3 PE=1 SV=2 8.51 3606.3 - 173007 - - - 1.9727 - 2.369 0.467 - 95.9 1 2 1 0.0044 20 0 0 0 5.88E+06 1.85E+06 - - - 3.5779 0.9999 221125_WJC_METTL3_EV_vs_WT_F04.22673.22673.3 0.000195 Oct-64 K.TVNELQNLTAAEVVVPR[166.11].D sp|Q9NZI8|IF2B1_HUMAN 1 1862.0137 0.04 55285 22673 3 1862.015485 621.6785 Insulin-like growth factor 2 mRNA-binding protein 1 OS=Homo sapiens OX=9606 GN=IGF2BP1 PE=1 SV=2 4.53 3607.5 - 172194 - - - 0.9603 - 2.277 0.482 - 115.3 1 2 0 0.0018 17 0 0 0 1.07E+05 2.50E+06 - - - 5.9921 1 221125_WJC_METTL3_EV_vs_WT_F04.22677.22677.2 8.44E-05 15/32 R.DWELLPSAAASAEPQSK.N sp|P48634|PRC2A_HUMAN 1 1798.8737 2.67 55287 22677 2 1798.869804 900.4441 Protein PRRC2A OS=Homo sapiens OX=9606 GN=PRRC2A PE=1 SV=3 4.14 3607.9 - 526032 - - - -2.1903 - 3.039 0.602 - 556 1 2 0 -0.0039 17 0 0 0 1.83E+07 6.85E+06 - - - 6.2189 0.9998 221125_WJC_METTL3_EV_vs_WT_F04.22678.22678.4 5.42E-09 13/114 K.FKIEANAGQLYLTGVVVLHK.D sp|O43395|PRPF3_HUMAN 1 2199.2416 2.68 55288 22678 4 2199.247739 550.8177 U4\U6 small nuclear ribonucleoprotein Prp3 OS=Homo sapiens OX=9606 GN=PRPF3 PE=1 SV=2 8.51 3608.1 - 329788 - - - 2.8028 - 2.582 0.585 - 69.9 1 2 1 0.0062 20 0 0 0 4.61E+06 1.72E+06 - - - 4.6333 0.9999 221125_WJC_METTL3_EV_vs_WT_F04.22680.22680.3 1.36E-06 Nov-84 K.GEWIKPGAIVIDC[160.03]GINYVPDDK.K "sp|P11586|C1TC_HUMAN,tr|F5H2F4|F5H2F4_HUMAN,tr|V9GZ78|V9GZ78_HUMAN,tr|V9GYY3|V9GYY3_HUMAN" 4 2458.2202 1.86 55290 22680 3 2458.217273 820.414 "C-1-tetrahydrofolate synthase, cytoplasmic OS=Homo sapiens OX=9606 GN=MTHFD1 PE=1 SV=4" 4.23 3608.3 - 609490 - - - -1.2098 - 2.307 0.491 - 75.6 1 2 0 -0.003 22 0 0 0 9.27E+06 4.99E+06 - - - 5.9952 0.9999 221125_WJC_METTL3_EV_vs_WT_F04.22696.22696.3 4.60E-06 17/76 R.SDLGPSYGGWQVLDATPQER.S "sp|Q08188|TGM3_HUMAN,tr|A0A494C0J7|A0A494C0J7_HUMAN" 2 2175.0233 9 55302 22696 3 2175.030302 726.015 Protein-glutamine gamma-glutamyltransferase E OS=Homo sapiens OX=9606 GN=TGM3 PE=1 SV=4 4.03 3610.4 - 642749 - - - 3.2367 - 2.961 0.492 - 306.1 1 2 0 0.007 20 0 0 0 1.71E+07 1.90E+06 - - - 6.6569 0.9999 221125_WJC_METTL3_EV_vs_WT_F04.22705.22705.4 0.000567 13/102 K.TEAEIAHIALETLEGHQR[166.11].A "sp|O75955|FLOT1_HUMAN,tr|A2AB10|A2AB10_HUMAN,tr|A0A140T910|A0A140T910_HUMAN,tr|A2AB09|A2AB09_HUMAN,tr|A2AB11|A2AB11_HUMAN,tr|A0A140T9C3|A0A140T9C3_HUMAN,tr|A0A140T9R1|A0A140T9R1_HUMAN,tr|A0A140T957|A0A140T957_HUMAN,tr|A0A140T9B1|A0A140T9B1_HUMAN,tr|A0A140T959|A0A140T959_HUMAN,tr|A2AB12|A2AB12_HUMAN,tr|A0A0G2JJQ6|A0A0G2JJQ6_HUMAN,tr|A0A140T9X0|A0A140T9X0_HUMAN,tr|A2AB13|A2AB13_HUMAN" 14 2027.0311 2.56 55309 22705 4 2027.031376 507.7651 Flotillin-1 OS=Homo sapiens OX=9606 GN=FLOT1 PE=1 SV=3 4.87 3611.6 - 309673 - - - 0.1174 - 2.601 0.42 - 135.3 1 2 0 0.0002 18 0 0 0 2.09E+07 8.17E+06 - - - 3.2091 0.9998 221125_WJC_METTL3_EV_vs_WT_F04.22710.22710.3 7.09E-06 18/80 R.EGLRVPGNIVYSSLC[160.03]GLGSEK.G "sp|Q6W2J9|BCOR_HUMAN,tr|H7BZ37|H7BZ37_HUMAN,tr|H7C2V9|H7C2V9_HUMAN,tr|A0A5F9ZGX7|A0A5F9ZGX7_HUMAN,tr|H7BYY2|H7BYY2_HUMAN,tr|H7C231|H7C231_HUMAN" 6 2234.1365 3.04 55312 22710 3 2234.141539 745.7194 BCL-6 corepressor OS=Homo sapiens OX=9606 GN=BCOR PE=1 SV=1 6.23 3612.2 - 868638 - - - 2.2474 - 3.528 0.518 - 363.8 1 2 1 0.005 21 0 0 0 9.50E+06 3.12E+06 - - - 7.3363 0.998 221125_WJC_METTL3_EV_vs_WT_F04.22711.22711.3 1.32E-08 16/88 F.SSLFDSSQVPANQGWGDGPLSSR.V "sp|Q8IWZ3|ANKH1_HUMAN,tr|A0A0A0MQZ8|A0A0A0MQZ8_HUMAN,tr|H0Y472|H0Y472_HUMAN,tr|H0Y7Y3|H0Y7Y3_HUMAN,tr|H0Y4P6|H0Y4P6_HUMAN,tr|H7C0V5|H7C0V5_HUMAN,tr|H0Y785|H0Y785_HUMAN" 7 2391.1091 1.44 55313 22711 3 2391.112557 798.0436 Ankyrin repeat and KH domain-containing protein 1 OS=Homo sapiens OX=9606 GN=ANKHD1 PE=1 SV=1 4.21 3612.4 - 750376 - - - 1.4387 - 3.538 0.552 - 191.2 1 1 0 0.0034 23 0 0 0 1.54E+07 1.06E+07 - - - 7.6575 1 221125_WJC_METTL3_EV_vs_WT_F04.22712.22712.3 9.51E-08 25/76 K.ISDSVLVDIKDTEPLIQTAK.T "sp|P48643|TCPE_HUMAN,tr|E9PCA1|E9PCA1_HUMAN,tr|B7ZAR1|B7ZAR1_HUMAN,tr|E7ENZ3|E7ENZ3_HUMAN" 4 2184.1889 0.79 55314 22712 3 2184.194484 729.0703 T-complex protein 1 subunit epsilon OS=Homo sapiens OX=9606 GN=CCT5 PE=1 SV=1 4.23 3612.5 - 688205 - - - 2.5428 - 4.624 0.564 - 913.4 1 2 1 0.0056 20 0 0 0 1.32E+09 1.68E+09 - - - 8.5414 1 221125_WJC_METTL3_EV_vs_WT_F04.22714.22714.4 9.14E-10 18/120 K.DHSSLLQGTLAEHFGVLPGPR.D sp|Q5VT52|RPRD2_HUMAN 1 2230.1495 1.19 55316 22714 4 2230.155124 558.5446 Regulation of nuclear pre-mRNA domain-containing protein 2 OS=Homo sapiens OX=9606 GN=RPRD2 PE=1 SV=1 5.99 3612.8 - 336140 - - - 2.5375 - 3.494 0.579 - 229.5 1 2 0 0.0057 21 0 0 0 6.19E+06 5.22E+06 - - - 4.6777 1 221125_WJC_METTL3_EV_vs_WT_F04.22722.22722.4 3.18E-10 24/102 K.TEAEIAHIALETLEGHQR.A "sp|O75955|FLOT1_HUMAN,tr|A2AB10|A2AB10_HUMAN,tr|A0A140T910|A0A140T910_HUMAN,tr|A2AB09|A2AB09_HUMAN,tr|A2AB11|A2AB11_HUMAN,tr|A0A140T9C3|A0A140T9C3_HUMAN,tr|A0A140T9R1|A0A140T9R1_HUMAN,tr|A0A140T957|A0A140T957_HUMAN,tr|A0A140T9B1|A0A140T9B1_HUMAN,tr|A0A140T959|A0A140T959_HUMAN,tr|A2AB12|A2AB12_HUMAN,tr|A0A0G2JJQ6|A0A0G2JJQ6_HUMAN,tr|A0A140T9X0|A0A140T9X0_HUMAN,tr|A2AB13|A2AB13_HUMAN" 14 2017.0229 2.56 55322 22722 4 2017.025761 505.263 Flotillin-1 OS=Homo sapiens OX=9606 GN=FLOT1 PE=1 SV=3 4.87 3613.7 - 1.02E+06 - - - 1.4343 - 3.588 0.58 - 419.3 1 2 0 0.0029 18 0 0 0 2.09E+07 8.17E+06 - - - 4.7112 0.9987 221125_WJC_METTL3_EV_vs_WT_F04.22725.22725.4 0.00141 16/126 R.THPVEIFYTPEPERDYLEAAIR.T sp|O43143|DHX15_HUMAN 1 2645.3126 1.08 55325 22725 4 2645.316446 662.3354 Pre-mRNA-splicing factor ATP-dependent RNA helicase DHX15 OS=Homo sapiens OX=9606 GN=DHX15 PE=1 SV=2 4.57 3614.1 - 648270 - - - 1.466 - 2.925 0.349 - 134 1 2 1 0.0039 22 0 0 0 1.30E+07 1.20E+07 - - - 2.6138 1 221125_WJC_METTL3_EV_vs_WT_F04.22726.22726.3 1.49E-12 17/72 K.HEALMSDLSAYGSSIQALR.E "sp|Q13813|SPTN1_HUMAN,tr|A0A0D9SF54|A0A0D9SF54_HUMAN,tr|A0A0D9SGF6|A0A0D9SGF6_HUMAN" 3 2047.9997 0.99 55326 22726 3 2048.00089 683.6738 "Spectrin alpha chain, non-erythrocytic 1 OS=Homo sapiens OX=9606 GN=SPTAN1 PE=1 SV=3" 5.32 3614.2 - 357072 - - - 0.5859 - 3.224 0.63 - 366.7 1 2 0 0.0012 19 0 0 0 2.70E+06 2.71E+06 - - - 8.4395 0.7697 221125_WJC_METTL3_EV_vs_WT_F04.22729.22729.4 0.167 11/102 R.K[136.11]IELFGR[166.11]PHNVQPNWITL.G sp|Q86U44|MTA70_HUMAN 1 2179.2021 0.02 55327 22729 4 2179.200812 545.8078 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 8.75 3614.6 - 1.27E+06 - - - -0.597 - 2.154 0.252 - 54.6 1 1 0 -0.0013 18 0 0 0 7.23E+07 3.60E+09 - - - 1.6819 1 221125_WJC_METTL3_EV_vs_WT_F04.22730.22730.3 1.51E-11 23/68 K.TEAEIAHIALETLEGHQR.A "sp|O75955|FLOT1_HUMAN,tr|A2AB10|A2AB10_HUMAN,tr|A0A140T910|A0A140T910_HUMAN,tr|A2AB09|A2AB09_HUMAN,tr|A2AB11|A2AB11_HUMAN,tr|A0A140T9C3|A0A140T9C3_HUMAN,tr|A0A140T9R1|A0A140T9R1_HUMAN,tr|A0A140T957|A0A140T957_HUMAN,tr|A0A140T9B1|A0A140T9B1_HUMAN,tr|A0A140T959|A0A140T959_HUMAN,tr|A2AB12|A2AB12_HUMAN,tr|A0A0G2JJQ6|A0A0G2JJQ6_HUMAN,tr|A0A140T9X0|A0A140T9X0_HUMAN,tr|A2AB13|A2AB13_HUMAN" 14 2017.0229 4.31 55328 22730 3 2017.028766 673.3482 Flotillin-1 OS=Homo sapiens OX=9606 GN=FLOT1 PE=1 SV=3 4.87 3614.7 - 952524 - - - 2.9241 - 3.629 0.615 - 470 1 2 0 0.0059 18 0 0 0 9.37E+06 2.17E+06 - - - 8.6046 1 221125_WJC_METTL3_EV_vs_WT_F04.22731.22731.3 3.31E-07 29/88 K.C[160.03]VDGKGPTEQLVSPEPEVYEILR.A "sp|O75688|PPM1B_HUMAN,tr|A0A3B3IS24|A0A3B3IS24_HUMAN,tr|C9JIR6|C9JIR6_HUMAN" 3 2614.2949 24.21 55329 22731 3 2614.289471 872.4389 Protein phosphatase 1B OS=Homo sapiens OX=9606 GN=PPM1B PE=1 SV=1 4.25 3614.9 - 1.67E+06 - - - -2.0648 - 4.404 0.656 - 902.9 1 2 1 -0.0054 23 0 0 0 1.07E+08 4.43E+06 - - - 9.3301 1 221125_WJC_METTL3_EV_vs_WT_F04.22734.22734.3 5.75E-14 27/108 R.VLHALQEAAPEVVQPTTVQSSTIPSLLR[166.11].G sp|Q9NUL7|DDX28_HUMAN 1 2993.6425 2.27 55332 22734 3 2993.63121 998.8881 Probable ATP-dependent RNA helicase DDX28 OS=Homo sapiens OX=9606 GN=DDX28 PE=1 SV=2 5.4 3615.2 - 919622 - - - -3.7733 - 4.753 0.745 - 715.7 1 2 0 -0.0113 28 0 0 0 2.53E+07 1.12E+07 - - - 10.4291 1 221125_WJC_METTL3_EV_vs_WT_F04.22735.22735.3 1.61E-13 19/68 K.RYDQDLC[160.03]YTDILFTEQER.G sp|Q15029|U5S1_HUMAN 1 2364.0692 1.24 55333 22735 3 2364.073507 789.0304 116 kDa U5 small nuclear ribonucleoprotein component OS=Homo sapiens OX=9606 GN=EFTUD2 PE=1 SV=1 4.11 3615.4 - 869279 - - - 1.8109 - 4.013 0.733 - 461.7 1 2 0 0.0043 18 0 0 0 1.87E+07 1.50E+07 - - - 10.1711 1 221125_WJC_METTL3_EV_vs_WT_F04.22745.22745.2 5.33E-13 21/38 K.ISDSVLVDIK[136.11]DTEPLIQTAK[136.11].T "sp|P48643|TCPE_HUMAN,tr|E9PCA1|E9PCA1_HUMAN,tr|B7ZAR1|B7ZAR1_HUMAN,tr|E7ENZ3|E7ENZ3_HUMAN" 4 2200.2173 1.16 55338 22745 2 2200.20254 1101.1159 T-complex protein 1 subunit epsilon OS=Homo sapiens OX=9606 GN=CCT5 PE=1 SV=1 4.23 3616.7 - 1.08E+06 - - - -6.7221 - 4.221 0.685 - 693.7 1 2 1 -0.0148 20 0 0 0 1.36E+08 1.17E+08 - - - 7.6362 0.9999 221125_WJC_METTL3_EV_vs_WT_F04.22755.22755.3 2.37E-08 18/52 K.SNSFFEGVDWEHIR.E sp|Q15208|STK38_HUMAN 1 1721.7798 6.66 55342 22755 3 1721.773056 574.9339 Serine\threonine-protein kinase 38 OS=Homo sapiens OX=9606 GN=STK38 PE=1 SV=1 4.65 3617.9 - 3.13E+06 - - - -3.9076 - 3.285 0.603 - 418.9 1 2 0 -0.0067 14 0 0 0 3.25E+08 4.88E+07 - - - 8.4218 1 221125_WJC_METTL3_EV_vs_WT_F04.22773.22773.3 1.87E-13 23/92 R.VETGVLK[136.11]PGMVVTFAPVNVTTEVK[136.11].S "sp|P68104|EF1A1_HUMAN,sp|Q5VTE0|EF1A3_HUMAN,tr|A0A7I2V659|A0A7I2V659_HUMAN,tr|A0A7I2V3H3|A0A7I2V3H3_HUMAN,tr|A0A7I2V5N4|A0A7I2V5N4_HUMAN,tr|A0A087WVQ9|A0A087WVQ9_HUMAN" 6 2530.4051 0.35 55347 22773 3 2530.396566 844.4757 Elongation factor 1-alpha 1 OS=Homo sapiens OX=9606 GN=EEF1A1 PE=1 SV=1 6.11 3620.4 - 9.27E+06 - - - -3.3916 - 4.331 0.67 - 490.9 1 2 0 -0.0086 24 0 0 0 1.68E+08 4.83E+08 - - - 9.4119 1 221125_WJC_METTL3_EV_vs_WT_F04.22779.22779.2 2.67E-14 24/38 K.ISDSVLVDIKDTEPLIQTAK.T "sp|P48643|TCPE_HUMAN,tr|E9PCA1|E9PCA1_HUMAN,tr|B7ZAR1|B7ZAR1_HUMAN,tr|E7ENZ3|E7ENZ3_HUMAN" 4 2184.1889 1.16 55349 22779 2 2184.186574 1093.1017 T-complex protein 1 subunit epsilon OS=Homo sapiens OX=9606 GN=CCT5 PE=1 SV=1 4.23 3621.2 - 3.44E+06 - - - -1.0787 - 4.465 0.714 - 1973.5 1 2 1 -0.0024 20 0 0 0 1.36E+08 1.17E+08 - - - 7.9925 0.9999 221125_WJC_METTL3_EV_vs_WT_F04.22789.22789.3 1.42E-05 16/76 K.ALPGQLKPFETLLSQNQGGK.T "sp|P09211|GSTP1_HUMAN,tr|A0A087X243|A0A087X243_HUMAN" 2 2125.1532 1.82 55352 22789 3 2125.149877 709.3917 Glutathione S-transferase P OS=Homo sapiens OX=9606 GN=GSTP1 PE=1 SV=2 8.64 3622.6 - 3.17E+06 - - - -1.542 - 2.558 0.456 - 223.5 1 2 0 -0.0033 20 0 0 0 1.72E+08 9.48E+07 - - - 5.9016 0.9652 221125_WJC_METTL3_EV_vs_WT_F04.22794.22794.2 3.48E-05 Dec-34 R.K[136.11]IELFGR[166.11]PHNVQPNWITL.G sp|Q86U44|MTA70_HUMAN 1 2179.2021 0.001 55353 22794 2 2179.1945 1090.6083 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 8.75 3623.3 - 6.87E+06 - - - -3.4935 - 2.265 0.586 - 187 1 1 0 -0.0076 18 0 0 0 0.00E+00 2.55E+08 - - - 5.3769 1 221125_WJC_METTL3_EV_vs_WT_F04.22803.22803.3 1.17E-10 24/92 R.VETGVLKPGMVVTFAPVNVTTEVK.S "sp|P68104|EF1A1_HUMAN,sp|Q5VTE0|EF1A3_HUMAN,tr|A0A7I2V659|A0A7I2V659_HUMAN,tr|A0A7I2V3H3|A0A7I2V3H3_HUMAN,tr|A0A7I2V5N4|A0A7I2V5N4_HUMAN,tr|A0A087WVQ9|A0A087WVQ9_HUMAN" 6 2514.3767 0.35 55355 22803 3 2514.364331 839.1329 Elongation factor 1-alpha 1 OS=Homo sapiens OX=9606 GN=EEF1A1 PE=1 SV=1 6.11 3624.6 - 4.45E+06 - - - -4.9384 - 4.42 0.661 - 487.8 1 2 0 -0.0124 24 0 0 0 1.68E+08 4.83E+08 - - - 9.3578 0.9999 221125_WJC_METTL3_EV_vs_WT_F04.22804.22804.3 0.0024 22/64 K.HNQLPLVIEFTEQTAPK[136.11].L "sp|P07237|PDIA1_HUMAN,tr|A0A7P0TA97|A0A7P0TA97_HUMAN,tr|A0A7P0T8C0|A0A7P0T8C0_HUMAN,tr|H7BZ94|H7BZ94_HUMAN,tr|A0A7P0TA71|A0A7P0TA71_HUMAN,tr|I3L4M2|I3L4M2_HUMAN,tr|A0A7P0T9D6|A0A7P0T9D6_HUMAN,tr|A0A7P0T9K9|A0A7P0T9K9_HUMAN,tr|H0Y3Z3|H0Y3Z3_HUMAN,tr|A0A7P0TA35|A0A7P0TA35_HUMAN,tr|I3L514|I3L514_HUMAN,tr|A0A7P0TB26|A0A7P0TB26_HUMAN,tr|A0A7P0T9U6|A0A7P0T9U6_HUMAN,tr|I3L3P5|I3L3P5_HUMAN,tr|A0A7P0T8X1|A0A7P0T8X1_HUMAN" 15 1972.0509 1.6 55356 22804 3 1972.044258 658.3576 Protein disulfide-isomerase OS=Homo sapiens OX=9606 GN=P4HB PE=1 SV=3 5.4 3624.7 - 1.90E+06 - - - -3.3818 - 3.83 0.56 - 891.5 1 2 0 -0.0067 17 0 0 0 1.52E+08 9.45E+07 - - - 8.1741 0.9997 221125_WJC_METTL3_EV_vs_WT_F04.22807.22807.3 0.00116 18/76 K.ALPGQLK[136.11]PFETLLSQNQGGK[136.11].T "sp|P09211|GSTP1_HUMAN,tr|A0A087X243|A0A087X243_HUMAN" 2 2141.1816 1.82 55359 22807 3 2141.17729 714.7345 Glutathione S-transferase P OS=Homo sapiens OX=9606 GN=GSTP1 PE=1 SV=2 8.64 3624.9 - 2.99E+06 - - - -1.9914 - 2.573 0.358 - 303.1 1 2 0 -0.0043 20 0 0 0 1.72E+08 9.49E+07 - - - 4.8229 0.9829 221125_WJC_METTL3_EV_vs_WT_F04.22813.22813.3 0.00016 14/68 R.K[136.11]IELFGR[166.11]PHNVQPNWITL.G sp|Q86U44|MTA70_HUMAN 1 2179.2021 0 55361 22813 3 2179.197066 727.408 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 8.75 3625.7 - 5.98E+07 - - - -2.316 - 2.285 0.44 - 214.2 1 1 0 -0.005 18 0 0 0 2.18E+06 3.01E+09 - - - 5.5019 1 221125_WJC_METTL3_EV_vs_WT_F04.22820.22820.3 1.33E-14 22/64 R.C[160.03]EMEQQSQEYQILLDVK.T sp|P08779|K1C16_HUMAN 1 2139.9817 166.12 55365 22820 3 2139.977887 714.3345 "Keratin, type I cytoskeletal 16 OS=Homo sapiens OX=9606 GN=KRT16 PE=1 SV=4" 4 3626.4 - 3.16E+06 - - - -1.7617 - 3.824 0.752 - 750 1 2 0 -0.0038 17 0 0 0 9.01E+07 5.42E+05 - - - 10.3115 0.9998 221125_WJC_METTL3_EV_vs_WT_F04.22822.22822.3 6.85E-09 26/104 K.SLPGQNEDLVLTGYQVDKNKDDELTGF.- sp|P01040|CYTA_HUMAN 1 2994.4458 999 55367 22822 3 2994.438079 999.1559 Cystatin-A OS=Homo sapiens OX=9606 GN=CSTA PE=1 SV=1 3.96 3626.7 - 3.59E+06 - - - -2.5871 - 4.115 0.498 - 429.3 1 2 2 -0.0077 27 0 0 0 8.34E+07 0.00E+00 - - - 7.3446 1 221125_WJC_METTL3_EV_vs_WT_F04.22825.22825.4 2.36E-12 26/174 R.TTGIVMDSGDGVTHTVPIYEGYALPHAILR[166.11].L "sp|P63261|ACTG_HUMAN,sp|P60709|ACTB_HUMAN,tr|A0A804GS07|A0A804GS07_HUMAN,tr|I3L3I0|I3L3I0_HUMAN,tr|E7EVS6|E7EVS6_HUMAN,tr|A0A6Q8PFE4|A0A6Q8PFE4_HUMAN,tr|I3L1U9|I3L1U9_HUMAN,tr|A0A2R8YEA7|A0A2R8YEA7_HUMAN,tr|A0A2R8Y793|A0A2R8Y793_HUMAN,tr|I3L4N8|I3L4N8_HUMAN" 10 3192.6153 0.92 55368 22825 4 3192.608142 799.1611 "Actin, cytoplasmic 2 OS=Homo sapiens OX=9606 GN=ACTG1 PE=1 SV=1" 5.2 3627.1 - 9.37E+06 - - - -2.2436 - 3.666 0.718 - 264.8 1 2 0 -0.0072 30 0 0 0 6.40E+08 6.98E+08 - - - 5.871 1 221125_WJC_METTL3_EV_vs_WT_F04.22826.22826.4 1.16E-08 24/174 R.TTGIVMDSGDGVTHTVPIYEGYALPHAILR.L "sp|P63261|ACTG_HUMAN,sp|P60709|ACTB_HUMAN,tr|A0A804GS07|A0A804GS07_HUMAN,tr|I3L3I0|I3L3I0_HUMAN,tr|E7EVS6|E7EVS6_HUMAN,tr|A0A6Q8PFE4|A0A6Q8PFE4_HUMAN,tr|I3L1U9|I3L1U9_HUMAN,tr|A0A2R8YEA7|A0A2R8YEA7_HUMAN,tr|A0A2R8Y793|A0A2R8Y793_HUMAN,tr|I3L4N8|I3L4N8_HUMAN" 10 3182.607 0.92 55369 22826 4 3182.601594 796.659 "Actin, cytoplasmic 2 OS=Homo sapiens OX=9606 GN=ACTG1 PE=1 SV=1" 5.2 3627.1 - 1.10E+07 - - - -1.7096 - 3.557 0.675 - 183.9 1 2 0 -0.0054 30 0 0 0 6.40E+08 6.98E+08 - - - 5.488 1 221125_WJC_METTL3_EV_vs_WT_F04.22832.22832.2 7.57E-10 15/42 L.C[160.03]LAISTPDAPATQDGVESLLQK[136.11].F "sp|Q86U44|MTA70_HUMAN,tr|B4E349|B4E349_HUMAN,tr|F5H6D8|F5H6D8_HUMAN,tr|H0YFV6|H0YFV6_HUMAN,tr|B4DTN4|B4DTN4_HUMAN" 5 2321.1664 0.001 55373 22832 2 2321.159419 1161.5905 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 4.03 3627.8 - 1.77E+06 - - - -3.0192 - 3.271 0.608 - 288.6 1 1 0 -0.007 22 0 0 0 0.00E+00 2.97E+07 - - - 6.4431 0.8574 221125_WJC_METTL3_EV_vs_WT_F04.22833.22833.3 0.0133 16/108 R.LASLMNLGMSSSLNQQGAHSALSSASTS.S "sp|P43243|MATR3_HUMAN,tr|D6RBS2|D6RBS2_HUMAN,tr|A8MXP9|A8MXP9_HUMAN,tr|D6R991|D6R991_HUMAN,tr|D6REK4|D6REK4_HUMAN,tr|A0A0R4J2E8|A0A0R4J2E8_HUMAN,tr|D6RCM3|D6RCM3_HUMAN,tr|D6R8Z5|D6R8Z5_HUMAN,tr|D6REM6|D6REM6_HUMAN" 9 2749.3011 - 55374 22833 3 2749.298158 917.441 Matrin-3 OS=Homo sapiens OX=9606 GN=MATR3 PE=1 SV=2 6.74 3627.9 - 3.29E+06 - - - -1.0675 - 2.102 0.248 - 143.2 1 1 0 -0.0029 28 0 0 0 - - - - - 3.0133 0.9995 221125_WJC_METTL3_EV_vs_WT_F04.22838.22838.4 0.000432 20/108 K.LDALSNFHFIPKPPVPEIK.V sp|O00566|MPP10_HUMAN 1 2161.1936 1.69 55377 22838 4 2161.19084 541.3057 U3 small nucleolar ribonucleoprotein protein MPP10 OS=Homo sapiens OX=9606 GN=MPHOSPH10 PE=1 SV=2 6.75 3628.6 - 3.17E+06 - - - -1.2595 - 3.244 0.317 - 277 1 2 0 -0.0027 19 0 0 0 7.19E+07 4.25E+07 - - - 2.3825 1 221125_WJC_METTL3_EV_vs_WT_F04.22839.22839.3 7.89E-07 21/64 K.ELTTEIDNNIEQISSYK.S "sp|P13645|K1C10_HUMAN,tr|A0A1B0GVI3|A0A1B0GVI3_HUMAN" 2 1995.9637 1701.14 55378 22839 3 1995.963622 666.3285 "Keratin, type I cytoskeletal 10 OS=Homo sapiens OX=9606 GN=KRT10 PE=1 SV=6" 4 3628.7 - 1.86E+06 - - - -0.0296 - 3.367 0.521 - 478.2 1 2 0 -0.0001 17 0 0 0 7.63E+08 4.49E+05 - - - 7.4156 1 221125_WJC_METTL3_EV_vs_WT_F04.22845.22845.3 3.96E-09 23/64 K.HNQLPLVIEFTEQTAPK.L "sp|P07237|PDIA1_HUMAN,tr|A0A7P0TA97|A0A7P0TA97_HUMAN,tr|A0A7P0T8C0|A0A7P0T8C0_HUMAN,tr|H7BZ94|H7BZ94_HUMAN,tr|A0A7P0TA71|A0A7P0TA71_HUMAN,tr|I3L4M2|I3L4M2_HUMAN,tr|A0A7P0T9D6|A0A7P0T9D6_HUMAN,tr|A0A7P0T9K9|A0A7P0T9K9_HUMAN,tr|H0Y3Z3|H0Y3Z3_HUMAN,tr|A0A7P0TA35|A0A7P0TA35_HUMAN,tr|I3L514|I3L514_HUMAN,tr|A0A7P0TB26|A0A7P0TB26_HUMAN,tr|A0A7P0T9U6|A0A7P0T9U6_HUMAN,tr|I3L3P5|I3L3P5_HUMAN,tr|A0A7P0T8X1|A0A7P0T8X1_HUMAN" 15 1964.0367 1.59 55382 22845 3 1964.034583 655.6862 Protein disulfide-isomerase OS=Homo sapiens OX=9606 GN=P4HB PE=1 SV=3 5.4 3629.4 - 3.96E+06 - - - -1.0916 - 3.965 0.62 - 1056.2 1 2 0 -0.0021 17 0 0 0 1.49E+08 9.37E+07 - - - 8.9318 0.9953 221125_WJC_METTL3_EV_vs_WT_F04.22848.22848.3 0.000542 16/68 R.FTPGTFTNQIQAAFREPR.L "sp|P08865|RSSA_HUMAN,tr|C9J9K3|C9J9K3_HUMAN,tr|A0A0C4DG17|A0A0C4DG17_HUMAN" 3 2080.049 0.43 55385 22848 3 2080.038904 694.357 40S ribosomal protein SA OS=Homo sapiens OX=9606 GN=RPSA PE=1 SV=4 9.6 3629.6 - 1.69E+06 - - - -4.8648 - 2.551 0.419 - 326.5 1 2 1 -0.0101 18 0 0 0 3.05E+07 7.11E+07 - - - 5.5406 1 221125_WJC_METTL3_EV_vs_WT_F04.22852.22852.3 1.49E-18 35/116 R.TTGIVMDSGDGVTHTVPIYEGYALPHAILR.L "sp|P63261|ACTG_HUMAN,sp|P60709|ACTB_HUMAN,tr|A0A804GS07|A0A804GS07_HUMAN,tr|I3L3I0|I3L3I0_HUMAN,tr|E7EVS6|E7EVS6_HUMAN,tr|A0A6Q8PFE4|A0A6Q8PFE4_HUMAN,tr|I3L1U9|I3L1U9_HUMAN,tr|A0A2R8YEA7|A0A2R8YEA7_HUMAN,tr|A0A2R8Y793|A0A2R8Y793_HUMAN,tr|I3L4N8|I3L4N8_HUMAN" 10 3182.607 0.82 55387 22852 3 3182.602883 1061.8763 "Actin, cytoplasmic 2 OS=Homo sapiens OX=9606 GN=ACTG1 PE=1 SV=1" 5.2 3630.1 - 2.08E+06 - - - -1.3046 - 5.435 0.734 - 913 1 2 0 -0.0042 30 0 0 0 5.01E+07 6.14E+07 - - - 10.6169 0.9999 221125_WJC_METTL3_EV_vs_WT_F04.22854.22854.3 1.91E-08 13/68 R.FTPGTFTNQIQAAFR[166.11]EPR[166.11].L "sp|P08865|RSSA_HUMAN,tr|C9J9K3|C9J9K3_HUMAN,tr|A0A0C4DG17|A0A0C4DG17_HUMAN" 3 2100.0656 0.44 55389 22854 3 2100.064218 701.0291 40S ribosomal protein SA OS=Homo sapiens OX=9606 GN=RPSA PE=1 SV=4 9.6 3630.3 - 3.17E+06 - - - -0.6405 - 2.627 0.553 - 181.6 1 2 1 -0.0013 18 0 0 0 3.11E+07 7.11E+07 - - - 7.1101 1 221125_WJC_METTL3_EV_vs_WT_F04.22858.22858.3 2.82E-20 36/116 R.TTGIVMDSGDGVTHTVPIYEGYALPHAILR[166.11].L "sp|P63261|ACTG_HUMAN,sp|P60709|ACTB_HUMAN,tr|A0A804GS07|A0A804GS07_HUMAN,tr|I3L3I0|I3L3I0_HUMAN,tr|E7EVS6|E7EVS6_HUMAN,tr|A0A6Q8PFE4|A0A6Q8PFE4_HUMAN,tr|I3L1U9|I3L1U9_HUMAN,tr|A0A2R8YEA7|A0A2R8YEA7_HUMAN,tr|A0A2R8Y793|A0A2R8Y793_HUMAN,tr|I3L4N8|I3L4N8_HUMAN" 10 3192.6153 0.82 55391 22858 3 3192.61145 1065.2124 "Actin, cytoplasmic 2 OS=Homo sapiens OX=9606 GN=ACTG1 PE=1 SV=1" 5.2 3630.8 - 2.71E+06 - - - -1.2075 - 5.306 0.768 - 975.3 1 2 0 -0.0039 30 0 0 0 5.01E+07 6.14E+07 - - - 10.9408 0.9999 221125_WJC_METTL3_EV_vs_WT_F04.22866.22866.3 7.03E-10 17/60 K.K[136.11]VSQEILELLNTTTAK[136.11].E "sp|Q86U44|MTA70_HUMAN,tr|H0YFV6|H0YFV6_HUMAN" 2 1803.0324 0.5 55397 22866 3 1803.02561 602.0181 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 6.14 3631.8 - 1.36E+06 - - - -3.7825 - 3.526 0.548 - 486 1 2 0 -0.0068 16 0 0 0 1.39E+07 2.79E+07 - - - 7.8812 1 221125_WJC_METTL3_EV_vs_WT_F04.22870.22870.3 3.19E-06 17/72 K.ANALHATNNLQIIPDFSLK[136.11].D "sp|Q9P2R3|ANFY1_HUMAN,tr|I3L1Z9|I3L1Z9_HUMAN" 2 2087.1255 0.94 55401 22870 3 2087.126993 696.7158 Rabankyrin-5 OS=Homo sapiens OX=9606 GN=ANKFY1 PE=1 SV=2 6.79 3632.3 - 733675 - - - 0.7206 - 3.727 0.535 - 299.7 1 2 0 0.0015 19 0 0 0 1.47E+07 1.56E+07 - - - 7.7365 0.9999 221125_WJC_METTL3_EV_vs_WT_F04.22873.22873.3 6.64E-05 20/64 K.AAIDWFDGKEFSGNPIK.V "sp|P35637|FUS_HUMAN,tr|H3BPE7|H3BPE7_HUMAN" 2 1893.9261 1.12 55402 22873 3 1893.924444 632.316 RNA-binding protein FUS OS=Homo sapiens OX=9606 GN=FUS PE=1 SV=1 4.56 3632.7 - 1.87E+06 - - - -0.8818 - 3.805 0.498 - 704.7 1 2 1 -0.0017 17 0 0 0 2.06E+08 1.84E+08 - - - 7.4677 0.9972 221125_WJC_METTL3_EV_vs_WT_F04.22874.22874.3 0.000954 Nov-76 R.SSPLKLEFDFTEDTGNIEAR.K "sp|O75410|TACC1_HUMAN,tr|E7EVI4|E7EVI4_HUMAN,tr|E5RFM9|E5RFM9_HUMAN,tr|R4GMT7|R4GMT7_HUMAN,tr|H0YAY0|H0YAY0_HUMAN,tr|E7ET87|E7ET87_HUMAN" 6 2268.091 0.7 55403 22874 3 2268.09503 757.0376 Transforming acidic coiled-coil-containing protein 1 OS=Homo sapiens OX=9606 GN=TACC1 PE=1 SV=2 4.18 3632.8 - 1.18E+06 - - - 1.7737 - 2.291 0.317 - 53.4 1 2 1 0.004 20 0 0 0 6.61E+06 9.39E+06 - - - 4.0843 0.9999 221125_WJC_METTL3_EV_vs_WT_F04.22875.22875.2 0.000125 13/32 K.DLDLLASVPSPSSSGSR.K "sp|Q8WU79|SMAP2_HUMAN,tr|A0A087WV97|A0A087WV97_HUMAN" 2 1686.8424 1.62 55404 22875 2 1686.841828 844.4285 Stromal membrane-associated protein 2 OS=Homo sapiens OX=9606 GN=SMAP2 PE=1 SV=1 4.21 3632.9 - 1.32E+06 - - - -0.3652 - 2.412 0.481 - 330.4 1 2 0 -0.0006 17 0 0 0 2.21E+08 1.37E+08 - - - 4.7581 0.9999 221125_WJC_METTL3_EV_vs_WT_F04.22878.22878.3 4.79E-05 Dec-52 K.HLTVEELFGTSLPK.E "sp|Q9NPI6|DCP1A_HUMAN,tr|A0A087WT55|A0A087WT55_HUMAN" 2 1569.8403 1.67 55407 22878 3 1569.83839 524.2874 mRNA-decapping enzyme 1A OS=Homo sapiens OX=9606 GN=DCP1A PE=1 SV=3 5.4 3633.3 - 478864 - - - -1.1906 - 2.37 0.435 - 175.7 1 2 0 -0.0019 14 0 0 0 2.31E+06 1.39E+06 - - - 5.6825 1 221125_WJC_METTL3_EV_vs_WT_F04.22885.22885.3 7.41E-08 20/88 K.GPHLANSILFQSSGLTNGIIEEK.D sp|Q9BVP2|GNL3_HUMAN 1 2424.2649 1.53 55412 22885 3 2424.26205 809.0956 Guanine nucleotide-binding protein-like 3 OS=Homo sapiens OX=9606 GN=GNL3 PE=1 SV=2 5.4 3634.1 - 1.54E+06 - - - -1.1711 - 3.926 0.545 - 333.3 1 2 0 -0.0028 23 0 0 0 1.98E+07 1.30E+07 - - - 7.8238 0.9997 221125_WJC_METTL3_EV_vs_WT_F04.22886.22886.3 0.00458 Dec-60 K.IDPQTGWPFFVDHNSR[166.11].T sp|O95817|BAG3_HUMAN 1 1924.9096 0.19 55413 22886 3 1924.90821 642.6438 BAG family molecular chaperone regulator 3 OS=Homo sapiens OX=9606 GN=BAG3 PE=1 SV=3 5.21 3634.2 - 522107 - - - -0.7044 - 2.099 0.344 - 142.9 1 2 0 -0.0014 16 0 0 0 1.58E+06 8.35E+06 - - - 4.2774 1 221125_WJC_METTL3_EV_vs_WT_F04.22889.22889.3 5.66E-13 21/64 K.AAIDWFDGK[136.11]EFSGNPIK[136.11].V "sp|P35637|FUS_HUMAN,tr|H3BPE7|H3BPE7_HUMAN" 2 1909.9545 1.12 55414 22889 3 1909.951472 637.6588 RNA-binding protein FUS OS=Homo sapiens OX=9606 GN=FUS PE=1 SV=1 4.56 3634.6 - 9.86E+06 - - - -1.5927 - 4.362 0.578 - 789.1 1 2 1 -0.003 17 0 0 0 2.06E+08 1.84E+08 - - - 8.7044 1 221125_WJC_METTL3_EV_vs_WT_F04.22892.22892.3 2.43E-13 33/96 K.GLDDLDADADDGWAGLHEEVDYSEK.L sp|Q5JSZ5|PRC2B_HUMAN 1 2734.1518 1.99 55417 22892 3 2734.150088 912.3912 Protein PRRC2B OS=Homo sapiens OX=9606 GN=PRRC2B PE=1 SV=2 3.66 3635 - 1.97E+06 - - - -0.6368 - 6.043 0.695 - 1636.9 1 2 0 -0.0017 25 0 0 0 2.10E+07 1.05E+07 - - - 10.4267 1 221125_WJC_METTL3_EV_vs_WT_F04.22895.22895.2 1.85E-07 16/32 K.AAIDWFDGKEFSGNPIK.V "sp|P35637|FUS_HUMAN,tr|H3BPE7|H3BPE7_HUMAN" 2 1893.9261 1.31 55420 22895 2 1893.924092 947.9703 RNA-binding protein FUS OS=Homo sapiens OX=9606 GN=FUS PE=1 SV=1 4.56 3635.4 - 650344 - - - -1.0676 - 3.679 0.614 - 973.3 1 2 1 -0.002 17 0 0 0 1.28E+07 9.75E+06 - - - 6.778 1 221125_WJC_METTL3_EV_vs_WT_F04.22898.22898.3 1.03E-08 21/92 K.YIAENGTDPINNQPLSEEQLIDIK.V "sp|Q9UMS4|PRP19_HUMAN,tr|F5GY56|F5GY56_HUMAN" 2 2713.3447 1.49 55421 22898 3 2713.34429 905.4555 Pre-mRNA-processing factor 19 OS=Homo sapiens OX=9606 GN=PRPF19 PE=1 SV=1 3.83 3635.8 - 7.08E+06 - - - -0.1349 - 3.528 0.635 - 390.6 1 2 0 -0.0004 24 0 0 0 1.21E+08 8.15E+07 - - - 8.5477 1 221125_WJC_METTL3_EV_vs_WT_F04.22899.22899.3 1.79E-09 20/92 K.YIAENGTDPINNQPLSEEQLIDIK[136.11].V "sp|Q9UMS4|PRP19_HUMAN,tr|F5GY56|F5GY56_HUMAN" 2 2721.3589 1.49 55422 22899 3 2721.357446 908.1269 Pre-mRNA-processing factor 19 OS=Homo sapiens OX=9606 GN=PRPF19 PE=1 SV=1 3.83 3635.8 - 5.38E+06 - - - -0.5181 - 3.614 0.652 - 351.4 1 2 0 -0.0014 24 0 0 0 1.21E+08 8.15E+07 - - - 8.7929 1 221125_WJC_METTL3_EV_vs_WT_F04.22904.22904.4 8.73E-11 24/138 R.ESLGLWGPEEEPHLLAGQWPGR[166.11]PK[136.11].L "sp|Q5JSZ5|PRC2B_HUMAN,tr|A0A804HKC3|A0A804HKC3_HUMAN" 2 2700.3779 1.79 55427 22904 4 2700.379149 676.1018 Protein PRRC2B OS=Homo sapiens OX=9606 GN=PRRC2B PE=1 SV=2 4.91 3636.2 - 1.28E+06 - - - 0.4607 - 4.044 0.618 - 260.3 1 2 0 0.0012 24 0 0 0 2.62E+07 1.46E+07 - - - 5.0532 1 221125_WJC_METTL3_EV_vs_WT_F04.22907.22907.2 2.83E-11 18/32 K.AAIDWFDGK[136.11]EFSGNPIK[136.11].V "sp|P35637|FUS_HUMAN,tr|H3BPE7|H3BPE7_HUMAN" 2 1909.9545 1.31 55430 22907 2 1909.954255 955.9845 RNA-binding protein FUS OS=Homo sapiens OX=9606 GN=FUS PE=1 SV=1 4.56 3636.6 - 683795 - - - -0.1356 - 3.818 0.608 - 1238.3 1 2 1 -0.0003 17 0 0 0 1.28E+07 9.75E+06 - - - 6.8254 1 221125_WJC_METTL3_EV_vs_WT_F04.22908.22908.2 6.79E-13 17/34 R.GTGQSDDSDIWDDTALIK[136.11].A "sp|Q16637|SMN_HUMAN,tr|E7EQZ4|E7EQZ4_HUMAN,tr|B4DP61|B4DP61_HUMAN,tr|A0A1W2PRV5|A0A1W2PRV5_HUMAN" 4 1943.884 1.75 55431 22908 2 1943.887554 972.9493 Survival motor neuron protein OS=Homo sapiens OX=9606 GN=SMN1 PE=1 SV=1 3.66 3636.8 - 553874 - - - 1.8381 - 3.721 0.725 - 1019.9 1 2 0 0.0036 18 0 0 0 1.28E+07 7.33E+06 - - - 7.6252 1 221125_WJC_METTL3_EV_vs_WT_F04.22914.22914.4 6.01E-12 22/138 R.ESLGLWGPEEEPHLLAGQWPGRPK.L "sp|Q5JSZ5|PRC2B_HUMAN,tr|A0A804HKC3|A0A804HKC3_HUMAN" 2 2682.3554 1.79 55435 22914 4 2682.353163 671.5961 Protein PRRC2B OS=Homo sapiens OX=9606 GN=PRRC2B PE=1 SV=2 4.91 3637.4 - 2.87E+06 - - - -0.847 - 3.767 0.612 - 190.2 1 2 0 -0.0023 24 0 0 0 2.62E+07 1.46E+07 - - - 4.9779 1 221125_WJC_METTL3_EV_vs_WT_F04.22915.22915.3 9.78E-16 18/64 R.SMDELNHDFQALALEGR.A "sp|Q14671|PUM1_HUMAN,tr|Q5T1Z8|Q5T1Z8_HUMAN,tr|H0YEH2|H0YEH2_HUMAN,tr|Q5T1Z4|Q5T1Z4_HUMAN,tr|E9PR38|E9PR38_HUMAN" 5 1944.9 3.83 55436 22915 3 1944.897515 649.3073 Pumilio homolog 1 OS=Homo sapiens OX=9606 GN=PUM1 PE=1 SV=3 4.31 3637.5 - 2.21E+06 - - - -1.2648 - 3.712 0.75 - 384.7 1 2 0 -0.0025 17 0 0 0 4.12E+07 1.07E+07 - - - 10.2145 1 221125_WJC_METTL3_EV_vs_WT_F04.22916.22916.3 1.36E-11 20/68 R.DGIDDESYGQIFK[136.11]PIISK[136.11].V sp|Q92769|HDAC2_HUMAN 1 2040.0386 2.12 55437 22916 3 2040.034149 681.0202 Histone deacetylase 2 OS=Homo sapiens OX=9606 GN=HDAC2 PE=1 SV=2 4.23 3637.6 - 1.48E+06 - - - -2.2 - 3.631 0.66 - 583.8 1 2 0 -0.0045 18 0 0 0 2.48E+08 1.17E+08 - - - 9.1081 0.9971 221125_WJC_METTL3_EV_vs_WT_F04.22917.22917.3 2.65E-05 16/80 K.DFLSC[160.03]R[166.11]PTEIPENDILLC[160.03]ESR[166.11].Y "sp|Q86U86|PB1_HUMAN,tr|E7EVG2|E7EVG2_HUMAN" 2 2583.2212 1.81 55438 22917 3 2584.217932 862.081 Protein polybromo-1 OS=Homo sapiens OX=9606 GN=PBRM1 PE=1 SV=1 4.18 3637.7 - 1.31E+06 - - - 385.8431 - 2.84 0.492 - 188.1 1 2 0 0.9967 21 0 0 0 1.16E+07 6.42E+06 - - - 6.2517 1 221125_WJC_METTL3_EV_vs_WT_F04.22918.22918.3 1.35E-10 19/64 R.SMDELNHDFQALALEGR[166.11].A "sp|Q14671|PUM1_HUMAN,tr|Q5T1Z8|Q5T1Z8_HUMAN,tr|H0YEH2|H0YEH2_HUMAN,tr|Q5T1Z4|Q5T1Z4_HUMAN,tr|E9PR38|E9PR38_HUMAN" 5 1954.9082 3.62 55439 22918 3 1954.904864 652.6434 Pumilio homolog 1 OS=Homo sapiens OX=9606 GN=PUM1 PE=1 SV=3 4.31 3637.9 - 1.24E+06 - - - -1.7295 - 3.537 0.585 - 446.2 1 2 0 -0.0034 17 0 0 0 3.90E+07 1.07E+07 - - - 8.2527 0.9999 221125_WJC_METTL3_EV_vs_WT_F04.22920.22920.3 1.50E-10 15/80 K.DFLSC[160.03]RPTEIPENDILLC[160.03]ESR.Y "sp|Q86U86|PB1_HUMAN,tr|E7EVG2|E7EVG2_HUMAN" 2 2563.2047 1.81 55441 22920 3 2563.195125 855.4088 Protein polybromo-1 OS=Homo sapiens OX=9606 GN=PBRM1 PE=1 SV=1 4.18 3638.1 - 697960 - - - -3.7254 - 2.831 0.622 - 284.2 1 2 0 -0.0095 21 0 0 0 1.16E+07 6.42E+06 - - - 7.9669 1 221125_WJC_METTL3_EV_vs_WT_F04.22922.22922.3 1.40E-09 17/84 R.R[166.11]GPFELEAFYSDPQGVPYPEAK[136.11].L "sp|Q92598|HS105_HUMAN,tr|A0A0A0MSM0|A0A0A0MSM0_HUMAN" 2 2514.2186 0.04 55442 22922 3 2514.218431 839.0801 Heat shock protein 105 kDa OS=Homo sapiens OX=9606 GN=HSPH1 PE=1 SV=1 4.41 3638.3 - 1.30E+06 - - - -0.0716 - 3.082 0.619 - 219.8 1 2 0 -0.0002 22 0 0 0 4.19E+06 1.09E+08 - - - 8.1097 1 221125_WJC_METTL3_EV_vs_WT_F04.22924.22924.3 1.25E-07 15/68 R.DGIDDESYGQIFKPIISK.V sp|Q92769|HDAC2_HUMAN 1 2024.0102 2.12 55443 22924 3 2024.012026 675.6774 Histone deacetylase 2 OS=Homo sapiens OX=9606 GN=HDAC2 PE=1 SV=2 4.23 3638.6 - 5.14E+06 - - - 0.8839 - 2.938 0.604 - 281.1 1 2 0 0.0018 18 0 0 0 2.48E+08 1.17E+08 - - - 7.9572 1 221125_WJC_METTL3_EV_vs_WT_F04.22929.22929.3 4.18E-07 14/56 K.DGQWFTDWDAVPHSR[166.11].H sp|Q08J23|NSUN2_HUMAN 1 1825.8048 0.75 55448 22929 3 1825.805503 609.6089 RNA cytosine C(5)-methyltransferase NSUN2 OS=Homo sapiens OX=9606 GN=NSUN2 PE=1 SV=2 4.41 3639.1 - 890333 - - - 0.4031 - 2.449 0.66 - 209.6 1 2 0 0.0007 15 0 0 0 3.13E+07 4.16E+07 - - - 8.2353 0.9997 221125_WJC_METTL3_EV_vs_WT_F04.22930.22930.3 2.35E-06 13/76 K.EK[136.11]EELIEEWQPEPLVPPVPK[136.11].D "sp|O15269|SPTC1_HUMAN,tr|A0A2R8Y6A2|A0A2R8Y6A2_HUMAN,tr|A0A2R8Y4S0|A0A2R8Y4S0_HUMAN" 3 2401.2752 2.8 55449 22930 3 2401.272378 801.4323 Serine palmitoyltransferase 1 OS=Homo sapiens OX=9606 GN=SPTLC1 PE=1 SV=1 4.21 3639.2 - 756560 - - - -1.1665 - 2.122 0.481 - 105.4 1 2 1 -0.0028 20 0 0 0 1.35E+07 4.82E+06 - - - 5.7271 1 221125_WJC_METTL3_EV_vs_WT_F04.22935.22935.2 1.01E-08 17/32 K.ELTTEIDNNIEQISSYK.S "sp|P13645|K1C10_HUMAN,tr|A0A1B0GVI3|A0A1B0GVI3_HUMAN" 2 1995.9637 999 55452 22935 2 1995.96257 998.9891 "Keratin, type I cytoskeletal 10 OS=Homo sapiens OX=9606 GN=KRT10 PE=1 SV=6" 4 3639.9 - 2.96E+06 - - - -0.5566 - 3.321 0.631 - 824.7 1 2 0 -0.0011 17 0 0 0 7.01E+08 0.00E+00 - - - 6.6521 1 221125_WJC_METTL3_EV_vs_WT_F04.22936.22936.3 1.72E-07 16/56 K.DGQWFTDWDAVPHSR.H sp|Q08J23|NSUN2_HUMAN 1 1815.7965 0.75 55453 22936 3 1815.796475 606.2728 RNA cytosine C(5)-methyltransferase NSUN2 OS=Homo sapiens OX=9606 GN=NSUN2 PE=1 SV=2 4.41 3640 - 1.53E+06 - - - -0.0121 - 2.948 0.588 - 314.5 1 2 0 0 15 0 0 0 3.13E+07 4.16E+07 - - - 7.9167 0.999 221125_WJC_METTL3_EV_vs_WT_F04.22939.22939.3 6.64E-09 17/96 L.AWHPQQSEVFVFGDENGTVSLVDTK[136.11].S "sp|Q9BQA1|MEP50_HUMAN,tr|H0Y711|H0Y711_HUMAN" 2 2797.3439 4.75 55456 22939 3 2797.345363 933.4552 Methylosome protein 50 OS=Homo sapiens OX=9606 GN=WDR77 PE=1 SV=1 4.31 3640.4 - 0 - - - 0.5323 - 3.592 0.623 - 288.4 1 1 0 0.0015 25 0 0 0 9.50E+06 2.00E+06 - - - 8.4273 1 221125_WJC_METTL3_EV_vs_WT_F04.22944.22944.3 2.24E-16 29/120 L.GGPGGFGPGGYPGGIHEVSVNQSLLQPLNVK.V sp|P35908|K22E_HUMAN 1 3031.5516 999 55458 22944 3 3031.550675 1011.5245 "Keratin, type II cytoskeletal 2 epidermal OS=Homo sapiens OX=9606 GN=KRT2 PE=1 SV=2" 6.75 3641 - 1.98E+06 - - - -0.2949 - 4.737 0.741 - 455.2 1 1 0 -0.0009 31 0 0 0 5.76E+07 0.00E+00 - - - 10.3796 1 221125_WJC_METTL3_EV_vs_WT_F04.22947.22947.3 1.88E-09 20/80 R.SINDPEHPLTLEELNVVEQVR.V "sp|Q9Y3D0|CIA2B_HUMAN,tr|H3BNV7|H3BNV7_HUMAN,tr|J3KS95|J3KS95_HUMAN" 3 2430.2391 5.93 55461 22947 3 2430.241941 811.087 Cytosolic iron-sulfur assembly component 2B OS=Homo sapiens OX=9606 GN=CIAO2B PE=1 SV=1 4.25 3641.2 - 3.54E+06 - - - 1.1822 - 3.608 0.531 - 374.5 1 2 0 0.0029 21 0 0 0 4.80E+07 8.10E+06 - - - 7.5356 1 221125_WJC_METTL3_EV_vs_WT_F04.22956.22956.2 2.35E-06 21/30 K.KVSQEILELLNTTTAK[136.11].E "sp|Q86U44|MTA70_HUMAN,tr|H0YFV6|H0YFV6_HUMAN" 2 1795.0182 - 55468 22956 2 1796.014363 898.5164 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 6.14 3642.2 - 3.30E+06 - - - 554.9431 - 3.818 0.529 - 1232.2 1 2 0 0.9961 16 0 0 0 - - - - - 5.9292 1 221125_WJC_METTL3_EV_vs_WT_F04.22959.22959.2 1.56E-08 23/30 K.K[136.11]VSQEILELLNTTTAK[136.11].E "sp|Q86U44|MTA70_HUMAN,tr|H0YFV6|H0YFV6_HUMAN" 2 1803.0324 0 55469 22959 2 1803.027919 902.5235 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 6.14 3642.6 - 1.44E+08 - - - -2.5019 - 4.368 0.623 - 1511 1 2 0 -0.0045 16 0 0 0 6.42E+08 1.73E+11 - - - 7.2657 0.9338 221125_WJC_METTL3_EV_vs_WT_F04.22970.22970.2 2.26E-06 17/32 K.DLDLLASVPSPSSSGSR[166.11].K "sp|Q8WU79|SMAP2_HUMAN,tr|A0A087WV97|A0A087WV97_HUMAN" 2 1696.8507 1.79 55476 22970 2 1697.860868 849.4326 Stromal membrane-associated protein 2 OS=Homo sapiens OX=9606 GN=SMAP2 PE=1 SV=1 4.21 3643.8 - 2.81E+06 - - - 595.3111 - 2.72 0.412 - 571.9 1 2 0 1.0102 17 0 0 0 2.08E+08 1.16E+08 - - - 4.2269 0.9999 221125_WJC_METTL3_EV_vs_WT_F04.22971.22971.4 2.07E-09 21/90 K.K[136.11]VSQEILELLNTTTAK[136.11].E "sp|Q86U44|MTA70_HUMAN,tr|H0YFV6|H0YFV6_HUMAN" 2 1803.0324 0.05 55477 22971 4 1803.025061 451.7654 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 6.14 3643.8 - 3.16E+06 - - - -4.087 - 4.3 0.593 - 485.4 1 2 0 -0.0074 16 0 0 0 3.31E+07 6.64E+08 - - - 4.8992 0.8855 221125_WJC_METTL3_EV_vs_WT_F04.22974.22974.2 0.032 14-Aug E.LLNTTTAK[136.11].E "sp|Q86U44|MTA70_HUMAN,tr|H0YFV6|H0YFV6_HUMAN" 2 868.5109 0 55480 22974 2 868.50935 435.2627 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 8.75 3644.1 - 1.92E+06 - - - -1.8227 - 1.572 0.252 - 153.3 1 1 0 -0.0016 8 0 0 0 7.78E+04 2.06E+08 - - - 2.266 1 221125_WJC_METTL3_EV_vs_WT_F04.22985.22985.2 1.31E-08 20/30 K.KVSQEILELLNTTTAK.E "sp|Q86U44|MTA70_HUMAN,tr|H0YFV6|H0YFV6_HUMAN" 2 1787.004 0 55485 22985 2 1788.005217 894.5093 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 6.14 3645.5 - 2.55E+06 - - - 560.2601 - 3.863 0.589 - 1220.9 1 2 0 1.0012 16 0 0 0 6.45E+08 1.74E+11 - - - 6.3996 1 221125_WJC_METTL3_EV_vs_WT_F04.23003.23003.3 4.69E-09 19/56 R.DHADSNIVIMLVGNK.S "sp|Q15907|RB11B_HUMAN,sp|P62491|RB11A_HUMAN,tr|B4DQU5|B4DQU5_HUMAN,tr|H3BMH2|H3BMH2_HUMAN,tr|H3BSC1|H3BSC1_HUMAN" 5 1624.8243 1.6 55491 23003 3 1624.822239 542.6154 Ras-related protein Rab-11B OS=Homo sapiens OX=9606 GN=RAB11B PE=1 SV=4 5.21 3647.9 - 6.89E+06 - - - -1.2629 - 3.523 0.671 - 704.7 1 2 0 -0.0021 15 0 0 0 1.43E+08 8.95E+07 - - - 9.3064 1 221125_WJC_METTL3_EV_vs_WT_F04.23009.23009.3 3.48E-08 18/56 R.DHADSNIVIMLVGNK[136.11].S "sp|Q15907|RB11B_HUMAN,sp|P62491|RB11A_HUMAN,tr|B4DQU5|B4DQU5_HUMAN,tr|H3BMH2|H3BMH2_HUMAN,tr|H3BSC1|H3BSC1_HUMAN" 5 1632.8385 1.6 55494 23009 3 1632.83084 545.2868 Ras-related protein Rab-11B OS=Homo sapiens OX=9606 GN=RAB11B PE=1 SV=4 5.21 3648.5 - 3.58E+06 - - - -4.6857 - 3.067 0.629 - 585.8 1 2 0 -0.0077 15 0 0 0 1.43E+08 8.95E+07 - - - 8.4749 1 221125_WJC_METTL3_EV_vs_WT_F04.23044.23044.2 5.26E-09 25/38 R.SASSASSLFSPSSTLFSSSR.L "sp|Q14671|PUM1_HUMAN,tr|Q5T1Z8|Q5T1Z8_HUMAN,tr|H0YDK8|H0YDK8_HUMAN,tr|H0YEH2|H0YEH2_HUMAN,tr|Q5T1Z4|Q5T1Z4_HUMAN,tr|E9PR38|E9PR38_HUMAN" 6 1991.9436 2.37 55500 23044 2 1991.93934 996.9791 Pumilio homolog 1 OS=Homo sapiens OX=9606 GN=PUM1 PE=1 SV=3 9.47 3653.8 - 3.79E+06 - - - -2.1456 - 3.612 0.642 - 636.1 1 2 0 -0.0043 20 0 0 0 8.24E+08 3.48E+08 - - - 6.9389 1 221125_WJC_METTL3_EV_vs_WT_F04.23054.23054.2 1.96E-10 19/38 R.SASSASSLFSPSSTLFSSSR[166.11].L "sp|Q14671|PUM1_HUMAN,tr|Q5T1Z8|Q5T1Z8_HUMAN,tr|H0YDK8|H0YDK8_HUMAN,tr|H0YEH2|H0YEH2_HUMAN,tr|Q5T1Z4|Q5T1Z4_HUMAN,tr|E9PR38|E9PR38_HUMAN" 6 2001.9519 2.37 55504 23054 2 2001.949849 1001.9832 Pumilio homolog 1 OS=Homo sapiens OX=9606 GN=PUM1 PE=1 SV=3 9.47 3655 - 6.31E+06 - - - -1.0165 - 3.859 0.642 - 610 1 2 0 -0.002 20 0 0 0 8.24E+08 3.48E+08 - - - 7.1022 1 221125_WJC_METTL3_EV_vs_WT_F04.23058.23058.3 4.66E-06 22/76 R.SASSASSLFSPSSTLFSSSR[166.11].L "sp|Q14671|PUM1_HUMAN,tr|Q5T1Z8|Q5T1Z8_HUMAN,tr|H0YDK8|H0YDK8_HUMAN,tr|H0YEH2|H0YEH2_HUMAN,tr|Q5T1Z4|Q5T1Z4_HUMAN,tr|E9PR38|E9PR38_HUMAN" 6 2001.9519 2.22 55506 23058 3 2001.952895 668.3246 Pumilio homolog 1 OS=Homo sapiens OX=9606 GN=PUM1 PE=1 SV=3 9.47 3655.5 - 5.89E+06 - - - 0.505 - 3.478 0.471 - 458.8 1 2 0 0.001 20 0 0 0 4.86E+08 2.19E+08 - - - 6.8148 1 221125_WJC_METTL3_EV_vs_WT_F04.23066.23066.3 2.18E-09 20/76 R.SASSASSLFSPSSTLFSSSR.L "sp|Q14671|PUM1_HUMAN,tr|Q5T1Z8|Q5T1Z8_HUMAN,tr|H0YDK8|H0YDK8_HUMAN,tr|H0YEH2|H0YEH2_HUMAN,tr|Q5T1Z4|Q5T1Z4_HUMAN,tr|E9PR38|E9PR38_HUMAN" 6 1991.9436 2.22 55508 23066 3 1991.937588 664.9885 Pumilio homolog 1 OS=Homo sapiens OX=9606 GN=PUM1 PE=1 SV=3 9.47 3656.6 - 1.05E+07 - - - -3.0252 - 3.16 0.611 - 269.5 1 2 0 -0.006 20 0 0 0 4.86E+08 2.19E+08 - - - 8.1417 1 221125_WJC_METTL3_EV_vs_WT_F04.23074.23074.2 2.47E-07 15/26 K.LISWYDNEFGYSNR.V "sp|P04406|G3P_HUMAN,tr|E7EUT5|E7EUT5_HUMAN" 2 1762.7951 1.55 55510 23074 2 1762.792661 882.4048 Glyceraldehyde-3-phosphate dehydrogenase OS=Homo sapiens OX=9606 GN=GAPDH PE=1 SV=3 4.37 3657.8 - 4.79E+06 - - - -1.3836 - 2.717 0.682 - 844.5 1 2 0 -0.0024 14 0 0 0 1.02E+08 6.55E+07 - - - 6.5858 1 221125_WJC_METTL3_EV_vs_WT_F04.23100.23100.3 1.41E-10 20/60 K.K[136.11]VSQEILELLNTTTAK[136.11].E "sp|Q86U44|MTA70_HUMAN,tr|H0YFV6|H0YFV6_HUMAN" 2 1803.0324 0.01 55512 23100 3 1803.027754 602.0181 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 6.14 3662 - 3.44E+09 - - - -2.5934 - 4.167 0.677 - 781.4 1 2 0 -0.0047 16 0 0 0 1.46E+09 1.51E+11 - - - 9.7486 1 221125_WJC_METTL3_EV_vs_WT_F04.23110.23110.3 1.14E-09 20/68 K.ISSIQSIVPALEIANAHR.K "sp|P10809|CH60_HUMAN,tr|A0A7I2V2X6|A0A7I2V2X6_HUMAN,tr|A0A7I2YQK6|A0A7I2YQK6_HUMAN,tr|A0A7I2V599|A0A7I2V599_HUMAN,tr|A0A7I2YQ71|A0A7I2YQ71_HUMAN,tr|A0A7I2V5M1|A0A7I2V5M1_HUMAN,tr|A0A7I2V5K3|A0A7I2V5K3_HUMAN,tr|A0A7I2V369|A0A7I2V369_HUMAN" 8 1918.0636 1.35 55513 23110 3 1918.0691 640.3618 "60 kDa heat shock protein, mitochondrial OS=Homo sapiens OX=9606 GN=HSPD1 PE=1 SV=2" 6.75 3663.6 - 5.46E+06 - - - 2.8623 - 3.229 0.561 - 396.7 1 2 0 0.0055 18 0 0 0 1.32E+09 9.80E+08 - - - 7.7119 1 221125_WJC_METTL3_EV_vs_WT_F04.23122.23122.3 1.37E-13 25/76 K.FEAHPNDLYVEGLPENIPFR.S "sp|P78347|GTF2I_HUMAN,tr|A0A494C0Q7|A0A494C0Q7_HUMAN,tr|A0A494C1K3|A0A494C1K3_HUMAN" 3 2356.1488 4.11 55517 23122 3 2356.147169 786.3902 General transcription factor II-I OS=Homo sapiens OX=9606 GN=GTF2I PE=1 SV=2 4.4 3665.3 - 3.42E+06 - - - -0.691 - 3.954 0.684 - 521.4 1 2 0 -0.0016 20 0 0 0 2.14E+08 5.21E+07 - - - 9.5006 1 221125_WJC_METTL3_EV_vs_WT_F04.23126.23126.3 9.08E-09 21/76 K.GDVAEGDLIEHFSQFGTVEK[136.11].A sp|Q13151|ROA0_HUMAN 1 2185.0419 2.15 55519 23126 3 2185.040178 729.3546 Heterogeneous nuclear ribonucleoprotein A0 OS=Homo sapiens OX=9606 GN=HNRNPA0 PE=1 SV=1 4.17 3665.7 - 9.35E+06 - - - -0.778 - 4.313 0.617 - 649.6 1 2 0 -0.0017 20 0 0 0 9.14E+08 4.25E+08 - - - 8.9644 1 221125_WJC_METTL3_EV_vs_WT_F04.23133.23133.3 3.21E-07 19/76 K.GDVAEGDLIEHFSQFGTVEK.A sp|Q13151|ROA0_HUMAN 1 2177.0277 2.15 55521 23133 3 2177.023813 726.6832 Heterogeneous nuclear ribonucleoprotein A0 OS=Homo sapiens OX=9606 GN=HNRNPA0 PE=1 SV=1 4.17 3666.7 - 2.18E+07 - - - -1.7754 - 3.583 0.552 - 424.2 1 2 0 -0.0039 20 0 0 0 9.20E+08 4.27E+08 - - - 7.7893 1 221125_WJC_METTL3_EV_vs_WT_F04.23156.23156.3 1.75E-09 19/76 K.FEAHPNDLYVEGLPENIPFR[166.11].S "sp|P78347|GTF2I_HUMAN,tr|A0A494C0Q7|A0A494C0Q7_HUMAN,tr|A0A494C1K3|A0A494C1K3_HUMAN" 3 2366.1571 4.03 55531 23156 3 2366.143567 789.7263 General transcription factor II-I OS=Homo sapiens OX=9606 GN=GTF2I PE=1 SV=2 4.4 3669.6 - 3.08E+06 - - - -5.7055 - 3.488 0.673 - 267.2 1 2 0 -0.0135 20 0 0 0 2.10E+08 5.21E+07 - - - 9.0704 0.9996 221125_WJC_METTL3_EV_vs_WT_F04.23165.23165.3 1.74E-05 21/76 R.GFGFVTFDDHDPVDKIVLQK.Y "sp|P22626|ROA2_HUMAN,tr|A0A024RA28|A0A024RA28_HUMAN,tr|A0A7I2V4N1|A0A7I2V4N1_HUMAN,tr|A0A7I2V4I6|A0A7I2V4I6_HUMAN,tr|A0A087WUI2|A0A087WUI2_HUMAN,tr|A0A7I2V4S4|A0A7I2V4S4_HUMAN,tr|A0A7I2V323|A0A7I2V323_HUMAN,tr|A0A7I2V3P1|A0A7I2V3P1_HUMAN,tr|A0A7I2V3P7|A0A7I2V3P7_HUMAN" 9 2276.1477 2.54 55533 23165 3 2276.139728 759.7232 Heterogeneous nuclear ribonucleoproteins A2\B1 OS=Homo sapiens OX=9606 GN=HNRNPA2B1 PE=1 SV=2 4.56 3670.9 - 2.76E+06 - - - -3.5173 - 3.331 0.546 - 322.6 1 2 1 -0.008 20 0 0 0 5.03E+07 1.98E+07 - - - 7.5443 1 221125_WJC_METTL3_EV_vs_WT_F04.23166.23166.3 4.85E-09 19/64 R.IQEIIEQLDVTTSEYEK.E "sp|P10809|CH60_HUMAN,tr|A0A7I2V2X6|A0A7I2V2X6_HUMAN,tr|A0A7I2YQK6|A0A7I2YQK6_HUMAN,tr|A0A7I2V599|A0A7I2V599_HUMAN" 4 2037.0154 0.9 55534 23166 3 2037.009837 680.0124 "60 kDa heat shock protein, mitochondrial OS=Homo sapiens OX=9606 GN=HSPD1 PE=1 SV=2" 3.91 3671 - 2.51E+06 - - - -2.7221 - 3.102 0.544 - 568.8 1 2 0 -0.0055 17 0 0 0 1.50E+08 1.67E+08 - - - 7.4634 0.9949 221125_WJC_METTL3_EV_vs_WT_F04.23173.23173.4 0.0032 16/114 R.GFGFVTFDDHDPVDK[136.11]IVLQK[136.11].Y "sp|P22626|ROA2_HUMAN,tr|A0A024RA28|A0A024RA28_HUMAN,tr|A0A7I2V4N1|A0A7I2V4N1_HUMAN,tr|A0A7I2V4I6|A0A7I2V4I6_HUMAN,tr|A0A087WUI2|A0A087WUI2_HUMAN,tr|A0A7I2V4S4|A0A7I2V4S4_HUMAN,tr|A0A7I2V323|A0A7I2V323_HUMAN,tr|A0A7I2V3P1|A0A7I2V3P1_HUMAN,tr|A0A7I2V3P7|A0A7I2V3P7_HUMAN" 9 2292.1761 1.7 55538 23173 4 2292.182816 574.0513 Heterogeneous nuclear ribonucleoproteins A2\B1 OS=Homo sapiens OX=9606 GN=HNRNPA2B1 PE=1 SV=2 4.56 3671.7 - 5.44E+06 - - - 2.9151 - 2.059 0.339 - 92.9 1 2 1 0.0067 20 0 0 0 1.66E+08 9.77E+07 - - - 2.4163 1 221125_WJC_METTL3_EV_vs_WT_F04.23177.23177.3 9.00E-10 16/60 K.K[136.11]VSQEILELLNTTTAK.E "sp|Q86U44|MTA70_HUMAN,tr|H0YFV6|H0YFV6_HUMAN" 2 1795.0182 - 55539 23177 3 1795.018577 599.3467 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 6.14 3672.3 - 9.68E+07 - - - 0.1933 - 3.291 0.616 - 457.3 2 2 0 0.0003 16 0 0 0 - - - - - 8.3248 1 221125_WJC_METTL3_EV_vs_WT_F04.23182.23182.2 2.66E-15 21/30 K.K[136.11]VSQEILELLNTTTAK[136.11].E "sp|Q86U44|MTA70_HUMAN,tr|H0YFV6|H0YFV6_HUMAN" 2 1803.0324 0 55542 23182 2 1803.028132 902.5235 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 6.14 3672.8 - 4.96E+08 - - - -2.3838 - 4.207 0.63 - 1166.7 1 2 0 -0.0043 16 0 0 0 5.57E+07 2.01E+10 - - - 7.2251 1 221125_WJC_METTL3_EV_vs_WT_F04.23183.23183.2 1.85E-10 20/32 R.IQEIIEQLDVTTSEYEK.E "sp|P10809|CH60_HUMAN,tr|A0A7I2V2X6|A0A7I2V2X6_HUMAN,tr|A0A7I2YQK6|A0A7I2YQK6_HUMAN,tr|A0A7I2V599|A0A7I2V599_HUMAN" 4 2037.0154 1.68 55543 23183 2 2037.015033 1019.515 "60 kDa heat shock protein, mitochondrial OS=Homo sapiens OX=9606 GN=HSPD1 PE=1 SV=2" 3.91 3672.9 - 3.46E+06 - - - -0.1713 - 3.953 0.64 - 1031.8 1 2 0 -0.0003 17 0 0 0 9.27E+07 5.51E+07 - - - 7.1471 1 221125_WJC_METTL3_EV_vs_WT_F04.23191.23191.2 3.09E-09 20/30 K.K[136.11]VSQEILELLNTTTAK.E "sp|Q86U44|MTA70_HUMAN,tr|H0YFV6|H0YFV6_HUMAN" 2 1795.0182 - 55547 23191 2 1796.015439 898.5164 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 6.14 3673.7 - 1.73E+07 - - - 555.5425 - 3.483 0.586 - 1016 1 2 0 0.9972 16 0 0 0 - - - - - 6.1241 0.9999 221125_WJC_METTL3_EV_vs_WT_F04.23197.23197.3 0.00171 16/68 K.ISSIQSIVPALEIANAHR[166.11].K "sp|P10809|CH60_HUMAN,tr|A0A7I2V2X6|A0A7I2V2X6_HUMAN,tr|A0A7I2YQK6|A0A7I2YQK6_HUMAN,tr|A0A7I2V599|A0A7I2V599_HUMAN,tr|A0A7I2YQ71|A0A7I2YQ71_HUMAN,tr|A0A7I2V5M1|A0A7I2V5M1_HUMAN,tr|A0A7I2V5K3|A0A7I2V5K3_HUMAN,tr|A0A7I2V369|A0A7I2V369_HUMAN" 8 1928.0719 1.35 55551 23197 3 1928.070736 643.6979 "60 kDa heat shock protein, mitochondrial OS=Homo sapiens OX=9606 GN=HSPD1 PE=1 SV=2" 6.75 3674.2 - 1.33E+07 - - - -0.5933 - 2.165 0.4 - 143.9 1 2 0 -0.0011 18 0 0 0 1.32E+09 9.80E+08 - - - 4.9227 1 221125_WJC_METTL3_EV_vs_WT_F04.23203.23203.4 1.89E-11 23/90 K.K[136.11]VSQEILELLNTTTAK[136.11].E "sp|Q86U44|MTA70_HUMAN,tr|H0YFV6|H0YFV6_HUMAN" 2 1803.0324 0.05 55555 23203 4 1803.029751 451.7654 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 6.14 3674.9 - 1.84E+06 - - - -1.4858 - 4.268 0.611 - 672.1 1 2 0 -0.0027 16 0 0 0 3.36E+07 6.67E+08 - - - 5.0546 1 221125_WJC_METTL3_EV_vs_WT_F04.23208.23208.3 1.92E-06 27/104 K.AAQYQVNQAAAAQAAATAAAMTQSAVK.S "sp|Q9NR56|MBNL1_HUMAN,tr|Q86VM6|Q86VM6_HUMAN,tr|A0A0A0MQX8|A0A0A0MQX8_HUMAN,tr|C9JP00|C9JP00_HUMAN" 4 2605.2918 1.68 55558 23208 3 2605.289949 869.4379 Muscleblind-like protein 1 OS=Homo sapiens OX=9606 GN=MBNL1 PE=1 SV=2 8.63 3675.4 - 8.15E+06 - - - -0.7293 - 4.94 0.641 - 308.3 1 2 0 -0.0019 27 0 0 0 6.76E+08 4.02E+08 - - - 9.361 1 221125_WJC_METTL3_EV_vs_WT_F04.23209.23209.2 2.04E-09 20/32 R.IQEIIEQLDVTTSEYEK[136.11].E "sp|P10809|CH60_HUMAN,tr|A0A7I2V2X6|A0A7I2V2X6_HUMAN,tr|A0A7I2YQK6|A0A7I2YQK6_HUMAN,tr|A0A7I2V599|A0A7I2V599_HUMAN" 4 2045.0296 1.68 55559 23209 2 2045.027974 1023.5221 "60 kDa heat shock protein, mitochondrial OS=Homo sapiens OX=9606 GN=HSPD1 PE=1 SV=2" 3.91 3675.5 - 1.91E+06 - - - -0.7863 - 3.919 0.629 - 1146.7 1 2 0 -0.0016 17 0 0 0 9.27E+07 5.51E+07 - - - 7.0443 0.9299 221125_WJC_METTL3_EV_vs_WT_F04.23213.23213.2 0.0239 14-Aug E.LLNTTTAK[136.11].E "sp|Q86U44|MTA70_HUMAN,tr|H0YFV6|H0YFV6_HUMAN" 2 868.5109 0.001 55561 23213 2 868.510254 435.2627 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 8.75 3676 - 906516 - - - -0.7818 - 1.553 0.256 - 155.2 1 1 0 -0.0007 8 0 0 0 0.00E+00 7.33E+07 - - - 2.2592 1 221125_WJC_METTL3_EV_vs_WT_F04.23219.23219.3 1.81E-10 22/88 K.AEIR[166.11]YEGILYTIDTENSTVALAK[136.11].V "sp|Q8ND56|LS14A_HUMAN,tr|I3L4Q1|I3L4Q1_HUMAN,tr|A0A140TA76|A0A140TA76_HUMAN,tr|K7EMZ9|K7EMZ9_HUMAN" 4 2587.35 0.73 55565 23219 3 2587.34519 863.4573 Protein LSM14 homolog A OS=Homo sapiens OX=9606 GN=LSM14A PE=1 SV=3 4.41 3676.7 - 3.69E+06 - - - -1.8664 - 4.434 0.618 - 506.3 1 2 1 -0.0048 23 0 0 0 7.77E+07 1.06E+08 - - - 8.9226 0.9459 221125_WJC_METTL3_EV_vs_WT_F04.23221.23221.2 0.0586 18-Oct L.LELLNTTTAK[136.11].E "sp|Q86U44|MTA70_HUMAN,tr|H0YFV6|H0YFV6_HUMAN" 2 1110.6376 0.001 55566 23221 2 1110.635129 556.3261 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 6 3676.9 - 855272 - - - -2.2158 - 2.319 0.261 - 324.5 1 1 0 -0.0025 10 0 0 0 0.00E+00 5.27E+07 - - - 3.3158 1 221125_WJC_METTL3_EV_vs_WT_F04.23223.23223.3 5.40E-09 20/92 R.ISSTSHTQDVVYLQQQLQAYAMER.E "sp|Q15643|TRIPB_HUMAN,tr|H0YJ97|H0YJ97_HUMAN" 2 2795.3548 1.84 55567 23223 3 2795.353526 932.7922 Thyroid receptor-interacting protein 11 OS=Homo sapiens OX=9606 GN=TRIP11 PE=1 SV=3 5.32 3677.1 - 1.63E+06 - - - -0.4711 - 4.374 0.657 - 501.7 1 2 0 -0.0013 24 0 0 0 4.24E+07 2.30E+07 - - - 9.2919 1 221125_WJC_METTL3_EV_vs_WT_F04.23226.23226.3 2.78E-07 22/88 K.AEIRYEGILYTIDTENSTVALAK.V "sp|Q8ND56|LS14A_HUMAN,tr|I3L4Q1|I3L4Q1_HUMAN,tr|A0A140TA76|A0A140TA76_HUMAN,tr|K7EMZ9|K7EMZ9_HUMAN" 4 2569.3275 0.73 55569 23226 3 2569.323243 857.4498 Protein LSM14 homolog A OS=Homo sapiens OX=9606 GN=LSM14A PE=1 SV=3 4.41 3677.4 - 2.99E+06 - - - -1.6759 - 4.325 0.634 - 459 1 2 1 -0.0043 23 0 0 0 7.77E+07 1.06E+08 - - - 9.0427 0.9982 221125_WJC_METTL3_EV_vs_WT_F04.23227.23227.4 1.20E-07 16/126 R.LTLYDIAHTPGVAADLSHIETK.A sp|P40926|MDHM_HUMAN 1 2364.2325 1.32 55570 23227 4 2365.238541 592.0654 "Malate dehydrogenase, mitochondrial OS=Homo sapiens OX=9606 GN=MDH2 PE=1 SV=3" 5.21 3677.5 - 3.02E+06 - - - 425.5144 - 3.391 0.482 - 114.5 1 2 0 1.006 22 0 0 0 1.37E+08 1.04E+08 - - - 3.5422 0.8442 221125_WJC_METTL3_EV_vs_WT_F04.23228.23228.2 0.00133 16-Oct L.ELLNTTTAK[136.11].E "sp|Q86U44|MTA70_HUMAN,tr|H0YFV6|H0YFV6_HUMAN" 2 997.5535 0.001 55571 23228 2 997.550873 499.784 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 6.1 3677.6 - 1.34E+06 - - - -2.6595 - 1.903 0.214 - 288.5 1 1 0 -0.0027 9 0 0 0 0.00E+00 5.52E+07 - - - 2.4823 1 221125_WJC_METTL3_EV_vs_WT_F04.23232.23232.2 9.49E-10 13/24 K.C[160.03]EFQDAYVLLSEK.K "sp|P10809|CH60_HUMAN,tr|A0A7I2V2X6|A0A7I2V2X6_HUMAN,tr|A0A7I2YQK6|A0A7I2YQK6_HUMAN,tr|A0A7I2V599|A0A7I2V599_HUMAN,tr|A0A7I2YQ71|A0A7I2YQ71_HUMAN,tr|A0A7I2V5M1|A0A7I2V5M1_HUMAN,tr|A0A7I2V5K3|A0A7I2V5K3_HUMAN,tr|A0A7I2V369|A0A7I2V369_HUMAN" 8 1600.7443 3.48 55572 23232 2 1600.741944 801.3794 "60 kDa heat shock protein, mitochondrial OS=Homo sapiens OX=9606 GN=HSPD1 PE=1 SV=2" 4.14 3678.2 - 806791 - - - -1.4781 - 2.742 0.675 - 504.7 1 2 0 -0.0024 13 0 0 0 4.10E+07 1.18E+07 - - - 6.6146 1 221125_WJC_METTL3_EV_vs_WT_F04.23234.23234.4 6.83E-15 31/156 K.AAQYQVNQAAAAQAAATAAAMTQSAVK.S "sp|Q9NR56|MBNL1_HUMAN,tr|Q86VM6|Q86VM6_HUMAN,tr|A0A0A0MQX8|A0A0A0MQX8_HUMAN,tr|C9JP00|C9JP00_HUMAN" 4 2605.2918 6.25 55573 23234 4 2605.294422 652.3302 Muscleblind-like protein 1 OS=Homo sapiens OX=9606 GN=MBNL1 PE=1 SV=2 8.63 3678.4 - 2.17E+06 - - - 0.9876 - 5.696 0.6 - 778.3 1 2 0 0.0026 27 0 0 0 3.71E+07 5.94E+06 - - - 4.992 1 221125_WJC_METTL3_EV_vs_WT_F04.23238.23238.3 1.84E-05 24/84 Y.SALILHDDEVTVTEDK[136.11]INALIK[136.11].A sp|P05386|RLA1_HUMAN 1 2452.3396 3.66 55574 23238 3 2452.335045 818.4538 60S acidic ribosomal protein P1 OS=Homo sapiens OX=9606 GN=RPLP1 PE=1 SV=1 4.43 3678.9 - 1.48E+06 - - - -1.8456 - 4.971 0.681 - 524.4 1 1 1 -0.0045 22 0 0 0 8.42E+07 2.30E+07 - - - 9.9331 1 221125_WJC_METTL3_EV_vs_WT_F04.23252.23252.2 8.18E-09 19/30 K.KVSQEILELLNTTTAK.E "sp|Q86U44|MTA70_HUMAN,tr|H0YFV6|H0YFV6_HUMAN" 2 1787.004 0 55580 23252 2 1788.000522 894.5093 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 6.14 3680.8 - 941768 - - - 557.6328 - 3.379 0.583 - 1024 1 2 0 0.9965 16 0 0 0 2.91E+07 1.23E+10 - - - 6.0276 1 221125_WJC_METTL3_EV_vs_WT_F04.23257.23257.3 1.37E-14 26/104 K.AAQYQVNQAAAAQAAATAAAMTQSAVK[136.11].S "sp|Q9NR56|MBNL1_HUMAN,tr|Q86VM6|Q86VM6_HUMAN,tr|A0A0A0MQX8|A0A0A0MQX8_HUMAN,tr|C9JP00|C9JP00_HUMAN" 4 2613.306 1.68 55582 23257 3 2614.301286 872.1093 Muscleblind-like protein 1 OS=Homo sapiens OX=9606 GN=MBNL1 PE=1 SV=2 8.63 3681.4 - 7.09E+06 - - - 380.8345 - 5.067 0.691 - 949.7 1 2 0 0.9952 27 0 0 0 6.76E+08 4.02E+08 - - - 9.7016 1 221125_WJC_METTL3_EV_vs_WT_F04.23298.23298.3 1.49E-06 24/92 K.QTQTFTTYSDNQPGVLIQVYEGER[166.11].A "sp|P11142|HSP7C_HUMAN,tr|E9PNE6|E9PNE6_HUMAN,tr|A8K7Q2|A8K7Q2_HUMAN,tr|E9PKE3|E9PKE3_HUMAN,tr|E9PS65|E9PS65_HUMAN" 5 2783.3278 0.17 55603 23298 3 2783.325728 928.7832 Heat shock cognate 71 kDa protein OS=Homo sapiens OX=9606 GN=HSPA8 PE=1 SV=1 4.14 3686.4 - 4.85E+06 - - - -0.7351 - 3.596 0.637 - 467.4 1 2 0 -0.002 24 0 0 0 2.16E+08 1.24E+09 - - - 8.6139 0.9999 221125_WJC_METTL3_EV_vs_WT_F04.23306.23306.4 1.59E-07 22/120 K.LFIGGLSFETTDDSLR[166.11]EHFEK[136.11].W "sp|P51991|ROA3_HUMAN,tr|A0A7I2V5D8|A0A7I2V5D8_HUMAN,tr|A0A7I2V2R3|A0A7I2V2R3_HUMAN,tr|A0A7I2V4J6|A0A7I2V4J6_HUMAN,tr|A0A7I2V4G0|A0A7I2V4G0_HUMAN,tr|A0A7I2V402|A0A7I2V402_HUMAN" 6 2458.2135 1.4 55609 23306 4 2458.212132 615.5607 Heterogeneous nuclear ribonucleoprotein A3 OS=Homo sapiens OX=9606 GN=HNRNPA3 PE=1 SV=2 4.5 3687.3 - 2.08E+06 - - - -0.5667 - 3.922 0.526 - 258.1 1 2 1 -0.0014 21 0 0 0 6.94E+07 4.96E+07 - - - 4.2558 0.9997 221125_WJC_METTL3_EV_vs_WT_F04.23321.23321.4 1.98E-06 14/120 K.LFIGGLSFETTDDSLREHFEK.W "sp|P51991|ROA3_HUMAN,tr|A0A7I2V5D8|A0A7I2V5D8_HUMAN,tr|A0A7I2V2R3|A0A7I2V2R3_HUMAN,tr|A0A7I2V4J6|A0A7I2V4J6_HUMAN,tr|A0A7I2V4G0|A0A7I2V4G0_HUMAN,tr|A0A7I2V402|A0A7I2V402_HUMAN" 6 2440.1911 1.4 55617 23321 4 2440.183628 611.055 Heterogeneous nuclear ribonucleoprotein A3 OS=Homo sapiens OX=9606 GN=HNRNPA3 PE=1 SV=2 4.5 3689 - 5.56E+06 - - - -3.0436 - 3.685 0.522 - 102.2 1 2 1 -0.0074 21 0 0 0 6.94E+07 4.96E+07 - - - 4.1987 1 221125_WJC_METTL3_EV_vs_WT_F04.23324.23324.3 3.59E-10 23/92 K.QTQTFTTYSDNQPGVLIQVYEGER.A "sp|P11142|HSP7C_HUMAN,tr|E9PNE6|E9PNE6_HUMAN,tr|A8K7Q2|A8K7Q2_HUMAN,tr|E9PKE3|E9PKE3_HUMAN,tr|E9PS65|E9PS65_HUMAN" 5 2773.3195 0.17 55618 23324 3 2773.3241 925.4471 Heat shock cognate 71 kDa protein OS=Homo sapiens OX=9606 GN=HSPA8 PE=1 SV=1 4.14 3689.4 - 2.23E+06 - - - 1.6572 - 3.379 0.628 - 487 1 2 0 0.0046 24 0 0 0 2.16E+08 1.24E+09 - - - 8.3683 0.9995 221125_WJC_METTL3_EV_vs_WT_F04.23326.23326.3 0.000228 16/60 R.DK[136.11]FPEVIINFPDPAQK[136.11].S "sp|Q00341|VIGLN_HUMAN,tr|A0A024R4E5|A0A024R4E5_HUMAN,tr|H7BZC3|H7BZC3_HUMAN,tr|H0Y394|H0Y394_HUMAN" 4 1872.9957 0.53 55619 23326 3 1873.001066 625.3392 Vigilin OS=Homo sapiens OX=9606 GN=HDLBP PE=1 SV=2 4.56 3689.6 - 909037 - - - 2.8916 - 3.101 0.449 - 211.2 1 2 1 0.0054 16 0 0 0 1.63E+07 3.07E+07 - - - 6.4483 1 221125_WJC_METTL3_EV_vs_WT_F04.23327.23327.3 1.19E-13 24/96 R.YNFPNPNPFVEDDMDK[136.11]NEIASVAYR[166.11].Y sp|O15371|EIF3D_HUMAN 1 2962.3562 2.08 55620 23327 3 2962.342089 988.4594 Eukaryotic translation initiation factor 3 subunit D OS=Homo sapiens OX=9606 GN=EIF3D PE=1 SV=1 4.11 3689.7 - 1.47E+06 - - - -4.778 - 3.949 0.754 - 399.1 1 2 1 -0.0142 25 0 0 0 1.93E+07 9.27E+06 - - - 10.1023 1 221125_WJC_METTL3_EV_vs_WT_F04.23334.23334.3 1.59E-10 21/84 K.EVEETDEMDQVELVDFDPNQER[166.11].R sp|P31689|DNJA1_HUMAN 1 2675.142 0.49 55624 23334 3 2675.136804 892.7213 DnaJ homolog subfamily A member 1 OS=Homo sapiens OX=9606 GN=DNAJA1 PE=1 SV=2 3.51 3690.6 - 3.30E+06 - - - -1.9446 - 3.81 0.69 - 312.8 1 2 0 -0.0052 22 0 0 0 3.68E+07 7.54E+07 - - - 9.4027 0.9997 221125_WJC_METTL3_EV_vs_WT_F04.23336.23336.3 0.000424 15/60 K.TKGVDEVTIVNILTNR.S "sp|P07355|ANXA2_HUMAN,tr|H0YMU9|H0YMU9_HUMAN,tr|H0YMD9|H0YMD9_HUMAN,tr|H0YKX9|H0YKX9_HUMAN,tr|H0YMM1|H0YMM1_HUMAN,tr|H0YLV6|H0YLV6_HUMAN,tr|H0YMD0|H0YMD0_HUMAN,tr|H0YKV8|H0YKV8_HUMAN,tr|H0YMW4|H0YMW4_HUMAN,tr|H0YN42|H0YN42_HUMAN,tr|A0A7I2V4P4|A0A7I2V4P4_HUMAN,tr|H0YMT9|H0YMT9_HUMAN,tr|H0YKZ7|H0YKZ7_HUMAN,tr|H0YKL9|H0YKL9_HUMAN,tr|H0YNB8|H0YNB8_HUMAN,tr|H0YKS4|H0YKS4_HUMAN" 16 1770.984 0.17 55626 23336 3 1770.986635 591.3353 Annexin A2 OS=Homo sapiens OX=9606 GN=ANXA2 PE=1 SV=2 5.74 3690.9 - 1.30E+06 - - - 1.5088 - 2.963 0.427 - 293.8 1 2 1 0.0027 16 0 0 0 2.58E+07 1.53E+08 - - - 6.0869 1 221125_WJC_METTL3_EV_vs_WT_F04.23337.23337.2 1.01E-11 19/46 K.QTQTFTTYSDNQPGVLIQVYEGER[166.11].A "sp|P11142|HSP7C_HUMAN,tr|E9PNE6|E9PNE6_HUMAN,tr|A8K7Q2|A8K7Q2_HUMAN,tr|E9PKE3|E9PKE3_HUMAN,tr|E9PS65|E9PS65_HUMAN" 5 2783.3278 0.04 55627 23337 2 2785.325447 1392.6712 Heat shock cognate 71 kDa protein OS=Homo sapiens OX=9606 GN=HSPA8 PE=1 SV=1 4.14 3691 - 1.22E+06 - - - 717.7283 - 3.713 0.737 - 648.9 1 2 0 1.9977 24 0 0 0 2.25E+06 5.52E+07 - - - 7.0824 1 221125_WJC_METTL3_EV_vs_WT_F04.23343.23343.3 1.73E-13 23/68 R.DGIDDESYEAIFK[136.11]PVMSK[136.11].V sp|Q13547|HDAC1_HUMAN 1 2058.9791 1.84 55631 23343 3 2058.974107 687.3336 Histone deacetylase 1 OS=Homo sapiens OX=9606 GN=HDAC1 PE=1 SV=1 4.11 3691.8 - 2.88E+06 - - - -2.4124 - 3.823 0.609 - 667.5 1 2 0 -0.005 18 0 0 0 1.31E+08 7.13E+07 - - - 8.6677 1 221125_WJC_METTL3_EV_vs_WT_F04.23344.23344.3 1.27E-10 19/68 R.DGIDDESYEAIFKPVMSK.V sp|Q13547|HDAC1_HUMAN 1 2042.9507 1.85 55632 23344 3 2042.940031 681.9908 Histone deacetylase 1 OS=Homo sapiens OX=9606 GN=HDAC1 PE=1 SV=1 4.11 3691.8 - 2.49E+06 - - - -5.2096 - 3.559 0.663 - 459.5 1 2 0 -0.0106 18 0 0 0 1.32E+08 7.13E+07 - - - 9.09 1 221125_WJC_METTL3_EV_vs_WT_F04.23348.23348.3 5.15E-11 17/60 K.K[136.11]VSQEILELLNTTTAK[136.11].E "sp|Q86U44|MTA70_HUMAN,tr|H0YFV6|H0YFV6_HUMAN" 2 1803.0324 0.01 55634 23348 3 1803.029601 602.0181 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 6.14 3692.3 - 3.78E+08 - - - -1.569 - 3.569 0.661 - 571.5 1 2 0 -0.0028 16 0 0 0 5.47E+08 5.61E+10 - - - 9.1732 1 221125_WJC_METTL3_EV_vs_WT_F04.23349.23349.2 8.91E-12 21/38 K.TIGGGDDSFNTFFSETGAGK[136.11].H "sp|Q6PEY2|TBA3E_HUMAN,sp|P0DPH7|TBA3C_HUMAN,sp|Q71U36|TBA1A_HUMAN,sp|P0DPH8|TBA3D_HUMAN,sp|P68363|TBA1B_HUMAN,sp|Q9BQE3|TBA1C_HUMAN,tr|F8W0F6|F8W0F6_HUMAN,tr|F8VS66|F8VS66_HUMAN,tr|F8VWV9|F8VWV9_HUMAN,tr|F8VRZ4|F8VRZ4_HUMAN,tr|F8VVB9|F8VVB9_HUMAN,tr|A0A1W2PQM2|A0A1W2PQM2_HUMAN,tr|F5H5D3|F5H5D3_HUMAN,tr|F8VRK0|F8VRK0_HUMAN,tr|F8VQQ4|F8VQQ4_HUMAN,tr|F8VX09|F8VX09_HUMAN,tr|A0A7P0Z4A1|A0A7P0Z4A1_HUMAN" 17 2014.9 0.57 55635 23349 2 2014.897541 1008.4573 Tubulin alpha-3E chain OS=Homo sapiens OX=9606 GN=TUBA3E PE=1 SV=2 4.03 3692.4 - 4.51E+06 - - - -1.203 - 3.441 0.729 - 840.2 1 2 0 -0.0024 20 0 0 0 3.81E+08 6.73E+08 - - - 7.4628 0.8202 221125_WJC_METTL3_EV_vs_WT_F04.23351.23351.3 1.79E-06 16/64 K.ELTTEIDNNIEQISSYK.S "sp|P13645|K1C10_HUMAN,tr|A0A1B0GVI3|A0A1B0GVI3_HUMAN" 2 1995.9637 999 55637 23351 3 1996.950227 666.3285 "Keratin, type I cytoskeletal 10 OS=Homo sapiens OX=9606 GN=KRT10 PE=1 SV=6" 4 3692.7 - 2.56E+06 - - - 494.2705 - 2.268 0.481 - 255.7 1 2 0 0.9865 17 0 0 0 2.85E+06 0.00E+00 - - - 5.6982 1 221125_WJC_METTL3_EV_vs_WT_F04.23352.23352.2 2.11E-09 21/38 K.TIGGGDDSFNTFFSETGAGK.H "sp|Q6PEY2|TBA3E_HUMAN,sp|P0DPH7|TBA3C_HUMAN,sp|Q71U36|TBA1A_HUMAN,sp|P0DPH8|TBA3D_HUMAN,sp|P68363|TBA1B_HUMAN,sp|Q9BQE3|TBA1C_HUMAN,tr|F8W0F6|F8W0F6_HUMAN,tr|F8VS66|F8VS66_HUMAN,tr|F8VWV9|F8VWV9_HUMAN,tr|F8VRZ4|F8VRZ4_HUMAN,tr|F8VVB9|F8VVB9_HUMAN,tr|A0A1W2PQM2|A0A1W2PQM2_HUMAN,tr|F5H5D3|F5H5D3_HUMAN,tr|F8VRK0|F8VRK0_HUMAN,tr|F8VQQ4|F8VQQ4_HUMAN,tr|F8VX09|F8VX09_HUMAN,tr|A0A7P0Z4A1|A0A7P0Z4A1_HUMAN" 17 2006.8858 0.57 55638 23352 2 2006.88542 1004.4502 Tubulin alpha-3E chain OS=Homo sapiens OX=9606 GN=TUBA3E PE=1 SV=2 4.03 3692.8 - 2.26E+06 - - - -0.1719 - 3.191 0.662 - 784.6 1 2 0 -0.0003 20 0 0 0 3.81E+08 6.73E+08 - - - 6.7832 1 221125_WJC_METTL3_EV_vs_WT_F04.23353.23353.3 7.28E-11 19/84 K.EVEETDEMDQVELVDFDPNQER.R sp|P31689|DNJA1_HUMAN 1 2665.1337 0.49 55639 23353 3 2665.129106 889.3852 DnaJ homolog subfamily A member 1 OS=Homo sapiens OX=9606 GN=DNAJA1 PE=1 SV=2 3.51 3692.9 - 2.26E+06 - - - -1.7372 - 3.738 0.713 - 261.3 1 2 0 -0.0046 22 0 0 0 3.68E+07 7.52E+07 - - - 9.614 0.9996 221125_WJC_METTL3_EV_vs_WT_F04.23354.23354.3 0.00639 14/60 K.SDALETLGFLNHYQMK[136.11].N "sp|P14866|HNRPL_HUMAN,tr|M0QYT0|M0QYT0_HUMAN,tr|A0A3B3ITJ4|A0A3B3ITJ4_HUMAN,tr|M0QXS5|M0QXS5_HUMAN,tr|M0R076|M0R076_HUMAN" 5 1873.9124 0.48 55640 23354 3 1873.912073 625.6447 Heterogeneous nuclear ribonucleoprotein L OS=Homo sapiens OX=9606 GN=HNRNPL PE=1 SV=2 5.3 3693 - 962433 - - - -0.1665 - 2.17 0.317 - 192.3 1 2 0 -0.0003 16 0 0 0 3.01E+06 6.23E+06 - - - 4.062 1 221125_WJC_METTL3_EV_vs_WT_F04.23357.23357.3 1.42E-08 14/76 K.TIGGGDDSFNTFFSETGAGK[136.11].H "sp|Q6PEY2|TBA3E_HUMAN,sp|P0DPH7|TBA3C_HUMAN,sp|Q71U36|TBA1A_HUMAN,sp|P0DPH8|TBA3D_HUMAN,sp|P68363|TBA1B_HUMAN,sp|Q9BQE3|TBA1C_HUMAN,tr|F8W0F6|F8W0F6_HUMAN,tr|F8VS66|F8VS66_HUMAN,tr|F8VWV9|F8VWV9_HUMAN,tr|F8VRZ4|F8VRZ4_HUMAN,tr|F8VVB9|F8VVB9_HUMAN,tr|A0A1W2PQM2|A0A1W2PQM2_HUMAN,tr|F5H5D3|F5H5D3_HUMAN,tr|F8VRK0|F8VRK0_HUMAN,tr|F8VQQ4|F8VQQ4_HUMAN,tr|F8VX09|F8VX09_HUMAN,tr|A0A7P0Z4A1|A0A7P0Z4A1_HUMAN" 17 2014.9 0.55 55641 23357 3 2014.897754 672.6406 Tubulin alpha-3E chain OS=Homo sapiens OX=9606 GN=TUBA3E PE=1 SV=2 4.03 3693.4 - 5.52E+06 - - - -1.0973 - 2.447 0.669 - 115.6 1 2 0 -0.0022 20 0 0 0 1.42E+08 2.58E+08 - - - 8.169 1 221125_WJC_METTL3_EV_vs_WT_F04.23358.23358.3 2.56E-10 21/76 K.TIGGGDDSFNTFFSETGAGK.H "sp|Q6PEY2|TBA3E_HUMAN,sp|P0DPH7|TBA3C_HUMAN,sp|Q71U36|TBA1A_HUMAN,sp|P0DPH8|TBA3D_HUMAN,sp|P68363|TBA1B_HUMAN,sp|Q9BQE3|TBA1C_HUMAN,tr|F8W0F6|F8W0F6_HUMAN,tr|F8VS66|F8VS66_HUMAN,tr|F8VWV9|F8VWV9_HUMAN,tr|F8VRZ4|F8VRZ4_HUMAN,tr|F8VVB9|F8VVB9_HUMAN,tr|A0A1W2PQM2|A0A1W2PQM2_HUMAN,tr|F5H5D3|F5H5D3_HUMAN,tr|F8VRK0|F8VRK0_HUMAN,tr|F8VQQ4|F8VQQ4_HUMAN,tr|F8VX09|F8VX09_HUMAN,tr|A0A7P0Z4A1|A0A7P0Z4A1_HUMAN" 17 2006.8858 0.55 55642 23358 3 2006.883782 669.9692 Tubulin alpha-3E chain OS=Homo sapiens OX=9606 GN=TUBA3E PE=1 SV=2 4.03 3693.5 - 2.57E+06 - - - -0.9881 - 2.836 0.677 - 291.9 1 2 0 -0.002 20 0 0 0 1.42E+08 2.58E+08 - - - 8.6162 0.9998 221125_WJC_METTL3_EV_vs_WT_F04.23362.23362.4 1.40E-07 23/132 K.TPELNLDQFHDKTPYTIMFGPDK.C "sp|P27824|CALX_HUMAN,tr|A0A7P0T937|A0A7P0T937_HUMAN,tr|A0A7P0T840|A0A7P0T840_HUMAN,tr|D6RFL1|D6RFL1_HUMAN,tr|A0A7P0Z4H2|A0A7P0Z4H2_HUMAN,tr|A0A7P0TB65|A0A7P0TB65_HUMAN,tr|A0A7P0TAE9|A0A7P0TAE9_HUMAN,tr|D6RGY2|D6RGY2_HUMAN,tr|A0A7P0T8G1|A0A7P0T8G1_HUMAN,tr|A0A7P0Z4D6|A0A7P0Z4D6_HUMAN,tr|A0A7P0Z484|A0A7P0Z484_HUMAN,tr|A0A7P0TAR9|A0A7P0TAR9_HUMAN,tr|A0A7P0T9L0|A0A7P0T9L0_HUMAN" 13 2706.3 0.97 55646 23362 4 2706.304847 677.5823 Calnexin OS=Homo sapiens OX=9606 GN=CANX PE=1 SV=2 4.66 3694 - 1.95E+06 - - - 1.808 - 3.052 0.509 - 302.4 1 2 1 0.0049 23 0 0 0 2.49E+07 2.56E+07 - - - 4.0165 0.9999 221125_WJC_METTL3_EV_vs_WT_F04.23373.23373.4 0.0021 22/138 K.QTQTFTTYSDNQPGVLIQVYEGER[166.11].A "sp|P11142|HSP7C_HUMAN,tr|E9PNE6|E9PNE6_HUMAN,tr|A8K7Q2|A8K7Q2_HUMAN,tr|E9PKE3|E9PKE3_HUMAN,tr|E9PS65|E9PS65_HUMAN" 5 2783.3278 0.11 55653 23373 4 2783.326683 696.8392 Heat shock cognate 71 kDa protein OS=Homo sapiens OX=9606 GN=HSPA8 PE=1 SV=1 4.14 3695.2 - 1.58E+06 - - - -0.392 - 2.947 0.448 - 185.1 1 2 0 -0.0011 24 0 0 0 2.40E+06 2.25E+07 - - - 3.472 0.8291 221125_WJC_METTL3_EV_vs_WT_F04.23378.23378.3 0.000266 18/60 R.HGVQELEIELQSQLSK.K "sp|P35527|K1C9_HUMAN,tr|K7EQQ3|K7EQQ3_HUMAN" 2 1836.9581 10.76 55658 23378 3 1837.943864 613.3267 "Keratin, type I cytoskeletal 9 OS=Homo sapiens OX=9606 GN=KRT9 PE=1 SV=3" 4.75 3695.9 - 1.30E+06 - - - 536.6056 - 2.688 0.449 - 346.9 1 2 0 0.9857 16 0 0 0 1.03E+07 9.60E+05 - - - 5.81 0.9999 221125_WJC_METTL3_EV_vs_WT_F04.23379.23379.4 1.12E-05 18/96 K.SKGLAPDLPEDLYHLIK.K "sp|P62277|RS13_HUMAN,tr|J3KMX5|J3KMX5_HUMAN" 2 1908.0357 1.14 55659 23379 4 1908.034557 478.0162 40S ribosomal protein S13 OS=Homo sapiens OX=9606 GN=RPS13 PE=1 SV=2 5.36 3696 - 617046 - - - -0.5802 - 3.379 0.507 - 296.5 1 2 1 -0.0011 17 0 0 0 1.36E+07 1.20E+07 - - - 4.0614 0.9994 221125_WJC_METTL3_EV_vs_WT_F04.23380.23380.3 0.000147 Dec-60 K.GLEEFFDDPKNWGQEK.V sp|Q9HD33|RM47_HUMAN 1 1937.8796 0.33 55660 23380 3 1937.874508 646.9671 "39S ribosomal protein L47, mitochondrial OS=Homo sapiens OX=9606 GN=MRPL47 PE=1 SV=2" 4.18 3696.2 - 559453 - - - -2.6059 - 2.095 0.496 - 120.1 1 2 1 -0.005 16 0 0 0 4.62E+06 1.41E+07 - - - 5.9661 1 221125_WJC_METTL3_EV_vs_WT_F04.23385.23385.2 1.94E-07 16/30 K.ASSTSPVEISEWLDQK.L "sp|P13804|ETFA_HUMAN,tr|H0YK49|H0YK49_HUMAN,tr|H0YL12|H0YL12_HUMAN,tr|H0YKF0|H0YKF0_HUMAN,tr|H0YLU7|H0YLU7_HUMAN,tr|H0YNX6|H0YNX6_HUMAN" 6 1775.8578 1.76 55663 23385 2 1775.858297 888.9362 "Electron transfer flavoprotein subunit alpha, mitochondrial OS=Homo sapiens OX=9606 GN=ETFA PE=1 SV=1" 4.14 3696.7 - 2.43E+06 - - - 0.3024 - 3.044 0.602 - 736.2 1 2 0 0.0005 16 0 0 0 4.47E+07 2.54E+07 - - - 6.224 1 221125_WJC_METTL3_EV_vs_WT_F04.23386.23386.3 7.45E-11 22/72 K.TIHLLTSLDEGIEQVQQSR.G "sp|Q8WV92|MITD1_HUMAN,tr|H7C3Q6|H7C3Q6_HUMAN" 2 2166.1281 1.45 55664 23386 3 2166.130956 723.05 MIT domain-containing protein 1 OS=Homo sapiens OX=9606 GN=MITD1 PE=1 SV=1 4.65 3696.8 - 2.38E+06 - - - 1.3365 - 4.405 0.591 - 764 1 2 0 0.0029 19 0 0 0 5.76E+07 3.98E+07 - - - 8.7711 1 221125_WJC_METTL3_EV_vs_WT_F04.23391.23391.3 5.29E-21 29/88 K.SENLGQGDKPDYFSSVATVVYLR.K sp|P27694|RFA1_HUMAN 1 2544.2496 1.14 55667 23391 3 2544.251764 849.0905 Replication protein A 70 kDa DNA-binding subunit OS=Homo sapiens OX=9606 GN=RPA1 PE=1 SV=2 4.56 3697.4 - 2.61E+06 - - - 0.8376 - 4.647 0.752 - 877.4 1 2 0 0.0021 23 0 0 0 1.57E+08 1.38E+08 - - - 10.5274 1 221125_WJC_METTL3_EV_vs_WT_F04.23393.23393.3 5.95E-11 25/96 R.EYVRPGLPVTFIDEVDSEEAPQAAK.L "sp|Q4KMQ1|TPRN_HUMAN,tr|H3BLU1|H3BLU1_HUMAN" 2 2759.3654 6.61 55669 23393 3 2759.370033 920.7957 Taperin OS=Homo sapiens OX=9606 GN=TPRN PE=1 SV=2 4.08 3697.6 - 1.68E+06 - - - 1.6823 - 4.577 0.703 - 585.9 1 2 0 0.0046 25 0 0 0 2.55E+07 3.86E+06 - - - 9.8758 1 221125_WJC_METTL3_EV_vs_WT_F04.23394.23394.3 1.48E-17 26/116 A.R[166.11]SLEPLPSSGPDFGGLGEEAEFVEVEPEAK[136.11].Q sp|Q9Y512|SAM50_HUMAN 1 3189.5473 1.81 55670 23394 3 3189.547938 1064.1897 Sorting and assembly machinery component 50 homolog OS=Homo sapiens OX=9606 GN=SAMM50 PE=1 SV=3 3.99 3697.8 - 1.24E+06 - - - 0.2079 - 4.708 0.732 - 572.5 1 1 0 0.0007 30 0 0 0 2.86E+07 1.58E+07 - - - 10.2652 1 221125_WJC_METTL3_EV_vs_WT_F04.23400.23400.3 2.04E-19 28/88 K.SENLGQGDK[136.11]PDYFSSVATVVYLR[166.11].K sp|P27694|RFA1_HUMAN 1 2562.2721 1.04 55674 23400 3 2562.278389 855.098 Replication protein A 70 kDa DNA-binding subunit OS=Homo sapiens OX=9606 GN=RPA1 PE=1 SV=2 4.56 3698.5 - 2.27E+06 - - - 2.4533 - 4.36 0.759 - 727.8 1 2 0 0.0063 23 0 0 0 1.56E+08 1.50E+08 - - - 10.4547 1 221125_WJC_METTL3_EV_vs_WT_F04.23401.23401.3 2.18E-11 27/96 K.ETVSQRPGATVPTDFATFPSSAFLR.A "sp|Q14203|DCTN1_HUMAN,tr|A0A804CDA6|A0A804CDA6_HUMAN,tr|E7EX90|E7EX90_HUMAN,tr|A0A7P0Z4C3|A0A7P0Z4C3_HUMAN,tr|E7EWF7|E7EWF7_HUMAN" 5 2681.3449 1.83 55675 23401 3 2681.347214 894.7889 Dynactin subunit 1 OS=Homo sapiens OX=9606 GN=DCTN1 PE=1 SV=3 6.17 3698.6 - 1.20E+06 - - - 0.8518 - 4.058 0.608 - 373.1 1 2 0 0.0023 25 0 0 0 4.30E+08 2.35E+08 - - - 8.5404 1 221125_WJC_METTL3_EV_vs_WT_F04.23402.23402.3 1.90E-05 Nov-60 K.ASSTSPVEISEWLDQK.L "sp|P13804|ETFA_HUMAN,tr|H0YK49|H0YK49_HUMAN,tr|H0YL12|H0YL12_HUMAN,tr|H0YKF0|H0YKF0_HUMAN,tr|H0YLU7|H0YLU7_HUMAN,tr|H0YNX6|H0YNX6_HUMAN" 6 1775.8578 0.23 55676 23402 3 1775.86093 592.9599 "Electron transfer flavoprotein subunit alpha, mitochondrial OS=Homo sapiens OX=9606 GN=ETFA PE=1 SV=1" 4.14 3698.7 - 950624 - - - 1.7851 - 2.731 0.534 - 175.5 1 2 0 0.0032 16 0 0 0 1.12E+07 4.84E+07 - - - 7.0705 1 221125_WJC_METTL3_EV_vs_WT_F04.23407.23407.4 4.06E-10 23/210 K.IDSVAAQPTATSPVVYTRPAISSFSSSGIGFGESLK.A sp|P49790|NU153_HUMAN 1 3626.8468 1.16 55679 23407 4 3626.855466 907.719 Nuclear pore complex protein Nup153 OS=Homo sapiens OX=9606 GN=NUP153 PE=1 SV=2 6.07 3699.4 - 857465 - - - 2.3872 - 4.268 0.588 - 216.7 1 2 0 0.0087 36 0 0 0 1.06E+07 9.16E+06 - - - 4.7693 1 221125_WJC_METTL3_EV_vs_WT_F04.23408.23408.2 6.24E-11 19/38 R.EATNDDPWGPSGQLMGEIAK[136.11].A sp|Q14677|EPN4_HUMAN 1 2122.9721 1.46 55680 23408 2 2122.967776 1062.4933 Clathrin interactor 1 OS=Homo sapiens OX=9606 GN=CLINT1 PE=1 SV=1 3.92 3699.5 - 1.30E+06 - - - -2.0292 - 3.718 0.667 - 927.7 1 2 0 -0.0043 20 0 0 0 8.13E+07 5.56E+07 - - - 7.1946 0.9996 221125_WJC_METTL3_EV_vs_WT_F04.23409.23409.4 0.113 17/96 K.SK[136.11]GLAPDLPEDLYHLIK[136.11].K "sp|P62277|RS13_HUMAN,tr|J3KMX5|J3KMX5_HUMAN" 2 1924.0641 1.14 55681 23409 4 1924.064178 482.0233 40S ribosomal protein S13 OS=Homo sapiens OX=9606 GN=RPS13 PE=1 SV=2 5.36 3699.7 - 788378 - - - 0.0592 - 2.856 0.411 - 275.8 1 2 1 0.0001 17 0 0 0 1.36E+07 1.20E+07 - - - 3.1677 0.9995 221125_WJC_METTL3_EV_vs_WT_F04.23410.23410.3 1.31E-11 16/68 K.AQDEGLLSDVVPFKVPGK.D "sp|P55084|ECHB_HUMAN,tr|F5GZQ3|F5GZQ3_HUMAN" 2 1898.0149 0.64 55682 23410 3 1898.023101 633.6789 "Trifunctional enzyme subunit beta, mitochondrial OS=Homo sapiens OX=9606 GN=HADHB PE=1 SV=3" 4.56 3699.8 - 526259 - - - 4.3056 - 2.938 0.612 - 266 1 2 1 0.0082 18 0 0 0 1.07E+07 1.68E+07 - - - 8.0446 1 221125_WJC_METTL3_EV_vs_WT_F04.23414.23414.2 5.82E-11 20/38 R.EATNDDPWGPSGQLMGEIAK.A sp|Q14677|EPN4_HUMAN 1 2114.9579 1.46 55684 23414 2 2114.958212 1058.4862 Clathrin interactor 1 OS=Homo sapiens OX=9606 GN=CLINT1 PE=1 SV=1 3.92 3700.3 - 3.08E+06 - - - 0.1551 - 3.576 0.715 - 983.3 1 2 0 0.0003 20 0 0 0 7.98E+07 5.48E+07 - - - 7.4547 1 221125_WJC_METTL3_EV_vs_WT_F04.23415.23415.3 1.77E-08 19/76 R.EATNDDPWGPSGQLMGEIAK[136.11].A sp|Q14677|EPN4_HUMAN 1 2122.9721 1.95 55685 23415 3 2122.972125 708.6646 Clathrin interactor 1 OS=Homo sapiens OX=9606 GN=CLINT1 PE=1 SV=1 3.92 3700.4 - 2.59E+06 - - - 0.0193 - 3.118 0.547 - 371.3 1 2 0 0 20 0 0 0 1.47E+08 7.53E+07 - - - 7.3974 1 221125_WJC_METTL3_EV_vs_WT_F04.23418.23418.3 2.06E-16 28/96 R.RFPGSMEGFVTLDEVGDEEDSELQK.L tr|A8MXP9|A8MXP9_HUMAN 1 2813.2702 2.15 55688 23418 3 2813.264478 938.764 Matrin-3 OS=Homo sapiens OX=9606 GN=MATR3 PE=1 SV=1 3.89 3700.7 - 1.09E+06 - - - -2.0233 - 5.176 0.738 - 941.1 1 2 0 -0.0057 25 0 0 0 5.74E+07 2.67E+07 - - - 10.5487 1 221125_WJC_METTL3_EV_vs_WT_F04.23419.23419.3 1.10E-08 22/68 K.AQDEGLLSDVVPFK[136.11]VPGK[136.11].D "sp|P55084|ECHB_HUMAN,tr|F5GZQ3|F5GZQ3_HUMAN" 2 1914.0433 0.62 55689 23419 3 1914.04436 639.0217 "Trifunctional enzyme subunit beta, mitochondrial OS=Homo sapiens OX=9606 GN=HADHB PE=1 SV=3" 4.56 3700.9 - 1.04E+06 - - - 0.5387 - 3.418 0.606 - 467.1 1 2 1 0.001 18 0 0 0 1.07E+07 1.72E+07 - - - 8.3565 1 221125_WJC_METTL3_EV_vs_WT_F04.23420.23420.4 6.43E-07 16/102 K.GTSIVVPEPLHFLLPGK[136.11]K[136.11].N "sp|Q9NUQ7|UFSP2_HUMAN,tr|D6RGX2|D6RGX2_HUMAN,tr|H0YA18|H0YA18_HUMAN" 3 1947.1528 1.12 55690 23420 4 1947.150844 487.7955 Ufm1-specific protease 2 OS=Homo sapiens OX=9606 GN=UFSP2 PE=1 SV=3 8.6 3701 - 787858 - - - -1.0148 - 2.797 0.525 - 180.8 1 2 0 -0.002 18 0 0 0 1.75E+07 1.56E+07 - - - 4.1474 0.9999 221125_WJC_METTL3_EV_vs_WT_F04.23426.23426.4 1.51E-07 22/144 K.C[160.03]LLDRVPEEEKDTNVQVLMVLGAGR.G "sp|O14744|ANM5_HUMAN,tr|H0YJ77|H0YJ77_HUMAN,tr|H0YJX6|H0YJX6_HUMAN" 3 2840.4524 1.33 55694 23426 4 2840.454827 711.1204 Protein arginine N-methyltransferase 5 OS=Homo sapiens OX=9606 GN=PRMT5 PE=1 SV=4 4.51 3701.8 - 1.30E+06 - - - 0.8372 - 3.768 0.554 - 333.2 1 2 2 0.0024 25 0 0 0 1.15E+07 8.62E+06 - - - 4.4694 0.9999 221125_WJC_METTL3_EV_vs_WT_F04.23429.23429.3 1.45E-05 18/92 K.QLGDNEAITQEIVGC[160.03]AHLENYALK[136.11].M "sp|Q9NP79|VTA1_HUMAN,tr|Q5TGM0|Q5TGM0_HUMAN,tr|A0A087WY55|A0A087WY55_HUMAN" 3 2693.321 0.67 55697 23429 3 2693.321656 898.781 Vacuolar protein sorting-associated protein VTA1 homolog OS=Homo sapiens OX=9606 GN=VTA1 PE=1 SV=1 4.4 3702.1 - 670746 - - - 0.2321 - 2.705 0.445 - 210.4 1 2 0 0.0006 24 0 0 0 6.28E+06 9.44E+06 - - - 5.8124 1 221125_WJC_METTL3_EV_vs_WT_F04.23434.23434.3 4.11E-06 18/68 K.R[166.11]IQEIIEQLDVTTSEYEK[136.11].E "sp|P10809|CH60_HUMAN,tr|A0A7I2V2X6|A0A7I2V2X6_HUMAN,tr|A0A7I2YQK6|A0A7I2YQK6_HUMAN,tr|A0A7I2V599|A0A7I2V599_HUMAN" 4 2211.139 1.21 55700 23434 3 2211.141013 738.0536 "60 kDa heat shock protein, mitochondrial OS=Homo sapiens OX=9606 GN=HSPD1 PE=1 SV=2" 4.25 3702.7 - 1.81E+06 - - - 0.9267 - 3.487 0.54 - 498.7 1 2 0 0.0021 18 0 0 0 2.37E+08 1.96E+08 - - - 7.6701 0.9299 221125_WJC_METTL3_EV_vs_WT_F04.23435.23435.4 0.000722 19/126 R.K[136.11]IELFGR[166.11]PHNVQPNWITLGNQL.D sp|Q86U44|MTA70_HUMAN 1 2591.4091 0.04 55701 23435 4 2591.41432 648.8596 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 8.75 3702.8 - 1.22E+06 - - - 1.9966 - 2.895 0.332 - 188.7 1 1 0 0.0052 22 0 0 0 2.76E+06 7.25E+07 - - - 2.4621 1 221125_WJC_METTL3_EV_vs_WT_F04.23438.23438.4 0.000365 18/102 K.GTSIVVPEPLHFLLPGKK.N "sp|Q9NUQ7|UFSP2_HUMAN,tr|D6RGX2|D6RGX2_HUMAN,tr|H0YA18|H0YA18_HUMAN" 3 1931.1244 1.12 55704 23438 4 1931.122854 483.7884 Ufm1-specific protease 2 OS=Homo sapiens OX=9606 GN=UFSP2 PE=1 SV=3 8.6 3703.2 - 696082 - - - -0.8109 - 3.105 0.508 - 281.1 1 2 0 -0.0016 18 0 0 0 1.75E+07 1.56E+07 - - - 4.0353 1 221125_WJC_METTL3_EV_vs_WT_F04.23441.23441.2 3.77E-09 19/30 K.K[136.11]VSQEILELLNTTTAK[136.11].E "sp|Q86U44|MTA70_HUMAN,tr|H0YFV6|H0YFV6_HUMAN" 2 1803.0324 0 55706 23441 2 1803.031243 902.5235 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 6.14 3703.5 - 6.23E+06 - - - -0.6583 - 3.956 0.63 - 1010.9 1 2 0 -0.0012 16 0 0 0 2.93E+07 1.26E+10 - - - 7.0749 1 221125_WJC_METTL3_EV_vs_WT_F04.23451.23451.3 0.000119 24/68 K.RIQEIIEQLDVTTSEYEK.E "sp|P10809|CH60_HUMAN,tr|A0A7I2V2X6|A0A7I2V2X6_HUMAN,tr|A0A7I2YQK6|A0A7I2YQK6_HUMAN,tr|A0A7I2V599|A0A7I2V599_HUMAN" 4 2193.1165 1.21 55713 23451 3 2193.118254 732.0461 "60 kDa heat shock protein, mitochondrial OS=Homo sapiens OX=9606 GN=HSPD1 PE=1 SV=2" 4.25 3704.7 - 4.56E+06 - - - 0.8025 - 4.134 0.571 - 977.2 1 2 0 0.0018 18 0 0 0 2.43E+08 2.01E+08 - - - 8.4397 0.9999 221125_WJC_METTL3_EV_vs_WT_F04.23452.23452.4 1.71E-09 20/150 R.ENYLEATVWIHGDNEENK[136.11]EIILQGLK[136.11].H "sp|Q9Y2L1|RRP44_HUMAN,tr|F2Z2C0|F2Z2C0_HUMAN,tr|G3V1J5|G3V1J5_HUMAN" 3 3070.5582 2.02 55714 23452 4 3070.561035 768.6468 Exosome complex exonuclease RRP44 OS=Homo sapiens OX=9606 GN=DIS3 PE=1 SV=2 4.41 3704.8 - 1.67E+06 - - - 0.9132 - 3.47 0.519 - 210.5 1 2 1 0.0028 26 0 0 0 2.30E+07 1.14E+07 - - - 4.135 0.9979 221125_WJC_METTL3_EV_vs_WT_F04.23454.23454.3 2.87E-09 20/64 K.K[136.11]VSQEILELLNTTTAK[136.11]E.Q "sp|Q86U44|MTA70_HUMAN,tr|H0YFV6|H0YFV6_HUMAN" 2 1932.075 0.36 55716 23454 3 1932.070929 645.0323 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 5.01 3704.9 - 1.82E+06 - - - -2.119 - 3.582 0.582 - 592.1 1 1 0 -0.0041 17 0 0 0 2.02E+07 5.61E+07 - - - 8.251 1 221125_WJC_METTL3_EV_vs_WT_F04.23459.23459.3 7.10E-11 22/96 K.ETVSQR[166.11]PGATVPTDFATFPSSAFLR[166.11].A "sp|Q14203|DCTN1_HUMAN,tr|A0A804CDA6|A0A804CDA6_HUMAN,tr|E7EX90|E7EX90_HUMAN,tr|A0A7P0Z4C3|A0A7P0Z4C3_HUMAN,tr|E7EWF7|E7EWF7_HUMAN" 5 2701.3615 1.83 55719 23459 3 2701.362345 901.4611 Dynactin subunit 1 OS=Homo sapiens OX=9606 GN=DCTN1 PE=1 SV=3 6.17 3705.6 - 5.96E+06 - - - 0.3239 - 3.604 0.577 - 288.6 1 2 0 0.0009 25 0 0 0 4.30E+08 2.35E+08 - - - 7.9223 1 221125_WJC_METTL3_EV_vs_WT_F04.23460.23460.3 1.91E-09 20/72 K.K[136.11]PVTDC[160.03]VISVPSFFTDAER[166.11].R sp|Q92598|HS105_HUMAN 1 2185.0844 0.09 55720 23460 3 2185.087858 729.3688 Heat shock protein 105 kDa OS=Homo sapiens OX=9606 GN=HSPH1 PE=1 SV=1 4.56 3705.6 - 2.72E+06 - - - 1.5706 - 3.803 0.603 - 416.4 1 2 0 0.0034 19 0 0 0 4.63E+06 5.19E+07 - - - 8.5437 0.9999 221125_WJC_METTL3_EV_vs_WT_F04.23461.23461.4 5.55E-05 23/150 R.ENYLEATVWIHGDNEENKEIILQGLK.H "sp|Q9Y2L1|RRP44_HUMAN,tr|F2Z2C0|F2Z2C0_HUMAN,tr|G3V1J5|G3V1J5_HUMAN" 3 3054.5298 2.02 55721 23461 4 3054.534777 764.6397 Exosome complex exonuclease RRP44 OS=Homo sapiens OX=9606 GN=DIS3 PE=1 SV=2 4.41 3705.7 - 2.25E+06 - - - 1.6192 - 3.261 0.542 - 321.9 1 2 1 0.0049 26 0 0 0 2.30E+07 1.14E+07 - - - 4.3151 1 221125_WJC_METTL3_EV_vs_WT_F04.23462.23462.3 1.94E-13 24/92 R.FLEQQNQVLQTKWELLQQVDTSTR.T sp|P04264|K2C1_HUMAN 1 2931.509 999 55722 23462 3 2931.510304 978.177 "Keratin, type II cytoskeletal 1 OS=Homo sapiens OX=9606 GN=KRT1 PE=1 SV=6" 4.68 3705.8 - 1.54E+06 - - - 0.4325 - 4.365 0.677 - 558.1 1 2 1 0.0013 24 0 0 0 1.84E+07 0.00E+00 - - - 9.5102 1 221125_WJC_METTL3_EV_vs_WT_F04.23464.23464.3 2.54E-15 28/92 R.HGLEVSEMAVSELPGNPNAVWTVR.R "sp|Q15393|SF3B3_HUMAN,tr|J3QKV4|J3QKV4_HUMAN" 2 2591.2802 2.75 55724 23464 3 2591.282724 864.7674 Splicing factor 3B subunit 3 OS=Homo sapiens OX=9606 GN=SF3B3 PE=1 SV=4 4.75 3706.1 - 950780 - - - 0.9655 - 4.559 0.633 - 637.5 1 2 0 0.0025 24 0 0 0 1.49E+07 5.43E+06 - - - 9.1203 1 221125_WJC_METTL3_EV_vs_WT_F04.23466.23466.3 1.12E-08 22/96 K.HNVEVLGILSDDVETDTVAPGENLK.L "sp|P15170|ERF3A_HUMAN,tr|H3BR35|H3BR35_HUMAN" 2 2663.329 0.92 55726 23466 3 2663.337759 888.7836 Eukaryotic peptide chain release factor GTP-binding subunit ERF3A OS=Homo sapiens OX=9606 GN=GSPT1 PE=1 SV=1 4.01 3706.3 - 650832 - - - 3.2865 - 4.25 0.641 - 398.1 1 2 0 0.0088 25 0 0 0 9.33E+06 1.02E+07 - - - 9.0129 1 221125_WJC_METTL3_EV_vs_WT_F04.23472.23472.3 1.40E-07 25/72 K.IR[166.11]ELESQISELQEDLESER[166.11].A sp|P35579|MYH9_HUMAN 1 2322.1454 1.07 55730 23472 3 2322.154161 775.0557 Myosin-9 OS=Homo sapiens OX=9606 GN=MYH9 PE=1 SV=4 4.06 3707.1 - 3.17E+06 - - - 3.7775 - 4.342 0.573 - 938 1 2 1 0.0088 19 0 0 0 7.76E+07 7.22E+07 - - - 8.5334 0.9999 221125_WJC_METTL3_EV_vs_WT_F04.23474.23474.3 1.13E-11 24/72 K.IRELESQISELQEDLESER.A sp|P35579|MYH9_HUMAN 1 2302.1288 1.07 55732 23474 3 2302.132286 768.3836 Myosin-9 OS=Homo sapiens OX=9606 GN=MYH9 PE=1 SV=4 4.06 3707.3 - 3.28E+06 - - - 1.493 - 4.162 0.57 - 874.8 1 2 1 0.0034 19 0 0 0 7.73E+07 7.22E+07 - - - 8.3974 0.9999 221125_WJC_METTL3_EV_vs_WT_F04.23475.23475.3 1.86E-07 15/52 K.R[166.11]LDQELDFILSQQK[136.11].E "sp|P37198|NUP62_HUMAN,tr|M0QXN5|M0QXN5_HUMAN" 2 1749.938 1.93 55733 23475 3 1749.944427 584.3199 Nuclear pore glycoprotein p62 OS=Homo sapiens OX=9606 GN=NUP62 PE=1 SV=3 4.56 3707.4 - 432808 - - - 3.6618 - 3.001 0.497 - 369.8 1 2 0 0.0064 14 0 0 0 3.44E+07 1.79E+07 - - - 6.9998 1 221125_WJC_METTL3_EV_vs_WT_F04.23476.23476.2 1.52E-09 14/32 K.AQYYLPDGSTIEIGPSR.F "sp|P61163|ACTZ_HUMAN,tr|R4GMT0|R4GMT0_HUMAN" 2 1865.9159 4.76 55734 23476 2 1865.922779 933.9652 Alpha-centractin OS=Homo sapiens OX=9606 GN=ACTR1A PE=1 SV=1 4.37 3707.6 - 381471 - - - 3.6636 - 3.013 0.694 - 391.5 1 2 0 0.0068 17 0 0 0 1.32E+07 2.78E+06 - - - 6.8764 1 221125_WJC_METTL3_EV_vs_WT_F04.23480.23480.3 5.18E-07 15/52 K.RLDQELDFILSQQK.E "sp|P37198|NUP62_HUMAN,tr|M0QXN5|M0QXN5_HUMAN" 2 1731.9155 1.93 55736 23480 3 1731.918083 578.3125 Nuclear pore glycoprotein p62 OS=Homo sapiens OX=9606 GN=NUP62 PE=1 SV=3 4.56 3708.1 - 1.55E+06 - - - 1.4631 - 3.063 0.567 - 324.2 1 2 0 0.0025 14 0 0 0 3.44E+07 1.79E+07 - - - 7.8356 1 221125_WJC_METTL3_EV_vs_WT_F04.23481.23481.3 3.34E-10 29/96 R.R[166.11]FPGSMEGFVTLDEVGDEEDSELQK[136.11].L tr|A8MXP9|A8MXP9_HUMAN 1 2831.2926 2.15 55737 23481 3 2831.291267 944.7715 Matrin-3 OS=Homo sapiens OX=9606 GN=MATR3 PE=1 SV=1 3.89 3708.2 - 885057 - - - -0.4849 - 5.725 0.67 - 1133.2 1 2 0 -0.0014 25 0 0 0 5.30E+07 2.47E+07 - - - 10.0237 0.904 221125_WJC_METTL3_EV_vs_WT_F04.23482.23482.3 0.000131 13/96 K.QPVPVGGAISTAQAQAFLGHLHQVQ.L "sp|P14859|PO2F1_HUMAN,tr|A0A0A0MT46|A0A0A0MT46_HUMAN" 2 2553.3452 - 55738 23482 3 2553.356083 852.1223 "POU domain, class 2, transcription factor 1 OS=Homo sapiens OX=9606 GN=POU2F1 PE=1 SV=2" 6.92 3708.3 - 985917 - - - 4.2603 - 2.668 0.391 - 120.8 1 1 0 0.0109 25 0 0 0 - - - - - 5.1539 0.9999 221125_WJC_METTL3_EV_vs_WT_F04.23487.23487.4 8.09E-07 20/144 K.ETVSQRPGATVPTDFATFPSSAFLR.A "sp|Q14203|DCTN1_HUMAN,tr|A0A804CDA6|A0A804CDA6_HUMAN,tr|E7EX90|E7EX90_HUMAN,tr|A0A7P0Z4C3|A0A7P0Z4C3_HUMAN,tr|E7EWF7|E7EWF7_HUMAN" 5 2681.3449 0.22 55741 23487 4 2681.351835 671.3435 Dynactin subunit 1 OS=Homo sapiens OX=9606 GN=DCTN1 PE=1 SV=3 6.17 3709 - 770026 - - - 2.5752 - 2.958 0.492 - 115.7 1 2 0 0.0069 25 0 0 0 1.23E+07 5.70E+07 - - - 3.8515 1 221125_WJC_METTL3_EV_vs_WT_F04.23497.23497.3 2.20E-07 21/80 K.QC[160.03]ANLQAAIADAEQRGEMALK.D "sp|P04259|K2C6B_HUMAN,sp|P02538|K2C6A_HUMAN" 2 2287.1049 5.14 55749 23497 3 2287.102244 763.3756 "Keratin, type II cytoskeletal 6B OS=Homo sapiens OX=9606 GN=KRT6B PE=1 SV=5" 4.68 3710.2 - 1.41E+06 - - - -1.1613 - 4.025 0.587 - 482.5 1 2 1 -0.0027 21 0 0 0 6.08E+07 1.18E+07 - - - 8.4223 0.9961 221125_WJC_METTL3_EV_vs_WT_F04.23500.23500.3 0.0249 11/108 K.SSVGETVYGGSDELSDDITQQQLLPGVK.D "sp|O00267|SPT5H_HUMAN,tr|M0QYL9|M0QYL9_HUMAN" 2 2921.4142 999 55752 23500 3 2921.416183 974.812 Transcription elongation factor SPT5 OS=Homo sapiens OX=9606 GN=SUPT5H PE=1 SV=1 3.77 3710.5 - 901894 - - - 0.6815 - 1.455 0.268 - 51.8 1 2 0 0.002 28 0 0 0 8.67E+06 0.00E+00 - - - 2.3901 0.9983 221125_WJC_METTL3_EV_vs_WT_F04.23501.23501.3 2.58E-12 16/92 Y.SAANYTNGSFGSNFVSAGIQTSFR.T "sp|P17844|DDX5_HUMAN,tr|J3KTA4|J3KTA4_HUMAN,tr|A0A0G2JLI4|A0A0G2JLI4_HUMAN" 3 2482.1513 12.56 55753 23501 3 2482.155753 828.391 Probable ATP-dependent RNA helicase DDX5 OS=Homo sapiens OX=9606 GN=DDX5 PE=1 SV=1 8.46 3710.6 - 762906 - - - 1.7876 - 3.166 0.65 - 177.8 1 1 0 0.0044 24 0 0 0 6.32E+06 5.03E+05 - - - 8.4623 0.9982 221125_WJC_METTL3_EV_vs_WT_F04.23509.23509.3 2.21E-09 22/92 T.GGAVFGEEGLTLNLEDVQPHDLGK.V "sp|P10809|CH60_HUMAN,tr|A0A7I2V2X6|A0A7I2V2X6_HUMAN,tr|A0A7I2YQK6|A0A7I2YQK6_HUMAN,tr|A0A7I2V599|A0A7I2V599_HUMAN" 4 2494.234 1.33 55759 23509 3 2494.237976 832.4186 "60 kDa heat shock protein, mitochondrial OS=Homo sapiens OX=9606 GN=HSPD1 PE=1 SV=2" 4.17 3711.6 - 3.49E+06 - - - 1.6009 - 3.417 0.6 - 386.1 1 1 0 0.004 24 0 0 0 4.11E+08 3.08E+08 - - - 8.0822 0.9975 221125_WJC_METTL3_EV_vs_WT_F04.23510.23510.3 0.000236 18/92 T.GGAVFGEEGLTLNLEDVQPHDLGK[136.11].V "sp|P10809|CH60_HUMAN,tr|A0A7I2V2X6|A0A7I2V2X6_HUMAN,tr|A0A7I2YQK6|A0A7I2YQK6_HUMAN,tr|A0A7I2V599|A0A7I2V599_HUMAN" 4 2502.2482 1.33 55760 23510 3 2502.247219 835.09 "60 kDa heat shock protein, mitochondrial OS=Homo sapiens OX=9606 GN=HSPD1 PE=1 SV=2" 4.17 3711.7 - 2.60E+06 - - - -0.3853 - 3.382 0.489 - 261.9 1 1 0 -0.001 24 0 0 0 4.11E+08 3.08E+08 - - - 6.8216 1 221125_WJC_METTL3_EV_vs_WT_F04.23513.23513.3 2.37E-08 17/52 R.SLHDALC[160.03]VLAQTVK[136.11].D "sp|P78371|TCPB_HUMAN,tr|F8VQ14|F8VQ14_HUMAN,tr|F5GWF6|F5GWF6_HUMAN" 3 1561.8378 0.48 55763 23513 3 1561.839278 521.6199 T-complex protein 1 subunit beta OS=Homo sapiens OX=9606 GN=CCT2 PE=1 SV=4 6.46 3712 - 1.15E+06 - - - 0.97 - 3.289 0.555 - 529.6 1 2 0 0.0015 14 0 0 0 9.68E+06 2.01E+07 - - - 7.8913 1 221125_WJC_METTL3_EV_vs_WT_F04.23514.23514.3 6.50E-11 19/84 R.GYDYGPHFQGILEASLEGDSGR.L "sp|P49327|FAS_HUMAN,tr|A0A0U1RQF0|A0A0U1RQF0_HUMAN" 2 2367.0768 0.19 55764 23514 3 2367.073075 790.0329 Fatty acid synthase OS=Homo sapiens OX=9606 GN=FASN PE=1 SV=3 4.31 3712.1 - 1.14E+06 - - - -1.5542 - 3.562 0.673 - 244.1 1 2 0 -0.0037 22 0 0 0 1.49E+07 7.97E+07 - - - 9.054 0.9998 221125_WJC_METTL3_EV_vs_WT_F04.23518.23518.3 4.03E-06 13/100 K.LGNNC[160.03]VFAPADVTSEK[136.11]DVQTALALAK[136.11].G "sp|Q99714|HCD2_HUMAN,tr|Q5H928|Q5H928_HUMAN,tr|A0A804HHW5|A0A804HHW5_HUMAN" 3 2747.4135 -1 55768 23518 3 2747.418695 916.8118 3-hydroxyacyl-CoA dehydrogenase type-2 OS=Homo sapiens OX=9606 GN=HSD17B10 PE=1 SV=3 4.56 3712.6 - 503092 - - - 1.8978 - 2.452 0.582 - 98.2 1 2 1 0.0052 26 0 0 0 0.00E+00 0.00E+00 - - - 7.0907 1 221125_WJC_METTL3_EV_vs_WT_F04.23520.23520.3 4.77E-18 21/100 R.DYTRPDLPSGDGQPALDPAIAAAFAK.E "sp|Q9UKA9|PTBP2_HUMAN,tr|B4DI28|B4DI28_HUMAN,tr|A0A6Q8PEZ3|A0A6Q8PEZ3_HUMAN,tr|A0A6Q8PH43|A0A6Q8PH43_HUMAN,tr|A0A7I2RVZ4|A0A7I2RVZ4_HUMAN,tr|A0A6Q8PFE6|A0A6Q8PFE6_HUMAN,tr|A0A6Q8PFC0|A0A6Q8PFC0_HUMAN,tr|A0A6Q8PH82|A0A6Q8PH82_HUMAN" 8 2656.3133 1.26 55770 23520 3 2656.322911 886.445 Polypyrimidine tract-binding protein 2 OS=Homo sapiens OX=9606 GN=PTBP2 PE=1 SV=1 4.14 3712.9 - 477882 - - - 3.6197 - 4.079 0.621 - 385 1 2 0 0.0096 26 0 0 0 8.19E+06 6.51E+06 - - - 8.6952 0.9997 221125_WJC_METTL3_EV_vs_WT_F04.23525.23525.3 5.13E-07 23/84 R.GYDYGPHFQGILEASLEGDSGR[166.11].L "sp|P49327|FAS_HUMAN,tr|A0A0U1RQF0|A0A0U1RQF0_HUMAN" 2 2377.085 0.18 55773 23525 3 2377.088999 793.369 Fatty acid synthase OS=Homo sapiens OX=9606 GN=FASN PE=1 SV=3 4.31 3713.5 - 1.94E+06 - - - 1.6722 - 3.824 0.27 - 450.8 1 2 0 0.004 22 0 0 0 1.49E+07 8.06E+07 - - - 4.7291 0.9999 221125_WJC_METTL3_EV_vs_WT_F04.23526.23526.3 9.75E-11 14/80 R.EAFLNTEDK[136.11]GDSLDSVEALIK[136.11].K "sp|Q13813|SPTN1_HUMAN,tr|A0A0D9SF54|A0A0D9SF54_HUMAN,tr|A0A0D9SGF6|A0A0D9SGF6_HUMAN" 3 2309.1609 1.74 55774 23526 3 2309.163703 770.7276 "Spectrin alpha chain, non-erythrocytic 1 OS=Homo sapiens OX=9606 GN=SPTAN1 PE=1 SV=3" 4.02 3713.6 - 1.18E+06 - - - 1.1974 - 3.288 0.591 - 219.9 1 2 1 0.0028 21 0 0 0 2.50E+07 1.43E+07 - - - 7.9819 1 221125_WJC_METTL3_EV_vs_WT_F04.23529.23529.3 1.41E-10 17/52 R.SLHDALC[160.03]VLAQTVK.D "sp|P78371|TCPB_HUMAN,tr|F8VQ14|F8VQ14_HUMAN,tr|F5GWF6|F5GWF6_HUMAN" 3 1553.8236 0.48 55777 23529 3 1553.824363 518.9485 T-complex protein 1 subunit beta OS=Homo sapiens OX=9606 GN=CCT2 PE=1 SV=4 6.46 3713.9 - 933926 - - - 0.5149 - 3.14 0.622 - 462.1 1 2 0 0.0008 14 0 0 0 9.68E+06 2.01E+07 - - - 8.5153 1 221125_WJC_METTL3_EV_vs_WT_F04.23533.23533.3 1.72E-06 16/56 K.DRPASGSPFQLFLSK.V "sp|Q96T88|UHRF1_HUMAN,tr|A0A087WWG9|A0A087WWG9_HUMAN,tr|A0A087WTW0|A0A087WTW0_HUMAN,tr|A0A087WVR3|A0A087WVR3_HUMAN" 4 1648.8573 1.5 55781 23533 3 1648.859039 550.6264 E3 ubiquitin-protein ligase UHRF1 OS=Homo sapiens OX=9606 GN=UHRF1 PE=1 SV=1 8.75 3714.4 - 578408 - - - 1.051 - 2.928 0.557 - 229.7 1 2 0 0.0017 15 0 0 0 8.13E+06 5.41E+06 - - - 7.5528 0.9997 221125_WJC_METTL3_EV_vs_WT_F04.23534.23534.3 1.99E-07 19/76 K.LRDQPSLVQAIFNGDPDEVR.A sp|O15084|ANR28_HUMAN 1 2268.1499 999 55782 23534 3 2268.158715 757.0572 Serine\threonine-protein phosphatase 6 regulatory ankyrin repeat subunit A OS=Homo sapiens OX=9606 GN=ANKRD28 PE=1 SV=5 4.23 3714.5 - 378799 - - - 3.9045 - 4.025 0.579 - 339.6 1 2 1 0.0089 20 0 0 0 3.21E+06 0.00E+00 - - - 8.3711 0.9965 221125_WJC_METTL3_EV_vs_WT_F04.23535.23535.4 0.00036 19/162 R.QTASVTLQAIAAQNAAVQAVNAHSNILK[136.11].A "sp|Q16891|MIC60_HUMAN,tr|B9A067|B9A067_HUMAN,tr|C9J406|C9J406_HUMAN,tr|H7C463|H7C463_HUMAN" 4 2839.5396 1.35 55783 23535 4 2840.537938 710.8922 MICOS complex subunit MIC60 OS=Homo sapiens OX=9606 GN=IMMT PE=1 SV=1 8.76 3714.7 - 367598 - - - 351.6007 - 3.362 0.453 - 107.1 1 2 0 0.9984 28 0 0 0 2.01E+08 1.50E+08 - - - 3.2688 0.9999 221125_WJC_METTL3_EV_vs_WT_F04.23542.23542.3 2.47E-09 24/108 R.QTASVTLQAIAAQNAAVQAVNAHSNILK.A "sp|Q16891|MIC60_HUMAN,tr|B9A067|B9A067_HUMAN,tr|C9J406|C9J406_HUMAN,tr|H7C463|H7C463_HUMAN" 4 2831.5254 1.29 55788 23542 3 2831.535316 944.8491 MICOS complex subunit MIC60 OS=Homo sapiens OX=9606 GN=IMMT PE=1 SV=1 8.76 3715.5 - 945326 - - - 3.5182 - 4.596 0.569 - 540.8 1 2 0 0.01 28 0 0 0 3.57E+08 2.76E+08 - - - 8.3899 0.9999 221125_WJC_METTL3_EV_vs_WT_F04.23543.23543.3 4.19E-08 16/80 R.NPPGFAFVEFEDPR[166.11]DAEDAVR[166.11].G "sp|Q16629|SRSF7_HUMAN,tr|C9JAB2|C9JAB2_HUMAN,tr|A0A0B4J1Z1|A0A0B4J1Z1_HUMAN" 3 2397.114 3.23 55789 23543 3 2397.116321 800.0453 Serine\arginine-rich splicing factor 7 OS=Homo sapiens OX=9606 GN=SRSF7 PE=1 SV=1 4.02 3715.6 - 802425 - - - 0.9561 - 2.802 0.545 - 136.5 1 2 1 0.0023 21 0 0 0 6.81E+07 2.11E+07 - - - 7.0858 1 221125_WJC_METTL3_EV_vs_WT_F04.23544.23544.4 8.73E-06 29/162 R.QTASVTLQAIAAQNAAVQAVNAHSNILK.A "sp|Q16891|MIC60_HUMAN,tr|B9A067|B9A067_HUMAN,tr|C9J406|C9J406_HUMAN,tr|H7C463|H7C463_HUMAN" 4 2831.5254 1.35 55790 23544 4 2831.527767 708.8886 MICOS complex subunit MIC60 OS=Homo sapiens OX=9606 GN=IMMT PE=1 SV=1 8.76 3715.8 - 771812 - - - 0.8522 - 5.358 0.542 - 423.7 1 2 0 0.0024 28 0 0 0 2.01E+08 1.50E+08 - - - 4.4641 1 221125_WJC_METTL3_EV_vs_WT_F04.23545.23545.4 0.00101 17/84 R.NLSTVMDEIHTVLKK.D sp|Q8IX12|CCAR1_HUMAN 1 1726.9288 4.23 55791 23545 4 1726.929789 432.7395 Cell division cycle and apoptosis regulator protein 1 OS=Homo sapiens OX=9606 GN=CCAR1 PE=1 SV=2 6.75 3715.9 - 536325 - - - 0.5982 - 3.076 0.481 - 196.8 1 2 0 0.001 15 0 0 0 4.72E+07 1.12E+07 - - - 3.8144 1 221125_WJC_METTL3_EV_vs_WT_F04.23550.23550.4 4.27E-11 24/144 R.LAAFADALEFADEEKESPVEFTGHK.L sp|Q5SY16|NOL9_HUMAN 1 2750.3075 0.94 55794 23550 4 2750.31044 688.5842 Polynucleotide 5'-hydroxyl-kinase NOL9 OS=Homo sapiens OX=9606 GN=NOL9 PE=1 SV=1 4.25 3716.6 - 1.24E+06 - - - 1.0537 - 4.518 0.66 - 388.7 1 2 1 0.0029 25 0 0 0 1.61E+07 1.71E+07 - - - 5.4496 0.9992 221125_WJC_METTL3_EV_vs_WT_F04.23551.23551.4 0.00124 21/138 R.QLPLLTSALHGLQQQHPAFSGVAR[166.11].L "sp|Q9H6R4|NOL6_HUMAN,tr|A0A0A0MRW6|A0A0A0MRW6_HUMAN" 2 2578.4008 1.12 55795 23551 4 2578.400564 645.6075 Nucleolar protein 6 OS=Homo sapiens OX=9606 GN=NOL6 PE=1 SV=2 9.76 3716.7 - 1.06E+06 - - - -0.076 - 2.389 0.301 - 175.7 1 2 0 -0.0002 24 0 0 0 1.30E+07 1.16E+07 - - - 2.1254 1 221125_WJC_METTL3_EV_vs_WT_F04.23552.23552.3 0.0194 16/60 K.KVSQEILELLNTTTAK[136.11].E "sp|Q86U44|MTA70_HUMAN,tr|H0YFV6|H0YFV6_HUMAN" 2 1795.0182 - 55796 23552 3 1795.019323 599.3467 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 6.14 3716.8 - 955732 - - - 0.6089 - 3.166 0.452 - 510.5 1 2 0 0.0011 16 0 0 0 - - - - - 6.5361 0.9999 221125_WJC_METTL3_EV_vs_WT_F04.23553.23553.3 0.000885 15/52 R.DKWLAPDGLIFPDR.A "sp|Q99873|ANM1_HUMAN,tr|E9PQ98|E9PQ98_HUMAN,tr|E9PKG1|E9PKG1_HUMAN,tr|E9PNR9|E9PNR9_HUMAN,tr|H0YDE4|H0YDE4_HUMAN,tr|E9PIX6|E9PIX6_HUMAN" 6 1641.8515 2.12 55797 23553 3 1641.852183 548.2911 Protein arginine N-methyltransferase 1 OS=Homo sapiens OX=9606 GN=PRMT1 PE=1 SV=3 4.43 3716.9 - 690400 - - - 0.4209 - 3.094 0.481 - 352.8 1 2 1 0.0007 14 0 0 0 1.93E+07 9.08E+06 - - - 6.9041 1 221125_WJC_METTL3_EV_vs_WT_F04.23560.23560.4 5.33E-05 19/138 R.QLPLLTSALHGLQQQHPAFSGVAR.L "sp|Q9H6R4|NOL6_HUMAN,tr|A0A0A0MRW6|A0A0A0MRW6_HUMAN" 2 2568.3925 1.12 55802 23560 4 2568.393495 643.1054 Nucleolar protein 6 OS=Homo sapiens OX=9606 GN=NOL6 PE=1 SV=2 9.76 3717.9 - 775414 - - - 0.3913 - 3.012 0.502 - 108.9 1 2 0 0.001 24 0 0 0 1.30E+07 1.16E+07 - - - 3.949 1 221125_WJC_METTL3_EV_vs_WT_F04.23562.23562.3 4.10E-13 31/108 R.QTASVTLQAIAAQNAAVQAVNAHSNILK[136.11].A "sp|Q16891|MIC60_HUMAN,tr|B9A067|B9A067_HUMAN,tr|C9J406|C9J406_HUMAN,tr|H7C463|H7C463_HUMAN" 4 2839.5396 1.29 55804 23562 3 2839.53817 947.5205 MICOS complex subunit MIC60 OS=Homo sapiens OX=9606 GN=IMMT PE=1 SV=1 8.76 3718.1 - 3.51E+06 - - - -0.4874 - 5.019 0.638 - 1029.9 1 2 0 -0.0014 28 0 0 0 3.57E+08 2.76E+08 - - - 9.3641 0.9789 221125_WJC_METTL3_EV_vs_WT_F04.23563.23563.4 0.000237 16/138 T.GGAVFGEEGLTLNLEDVQPHDLGK[136.11].V "sp|P10809|CH60_HUMAN,tr|A0A7I2V2X6|A0A7I2V2X6_HUMAN,tr|A0A7I2YQK6|A0A7I2YQK6_HUMAN,tr|A0A7I2V599|A0A7I2V599_HUMAN" 4 2502.2482 1.25 55805 23563 4 2502.250119 626.5693 "60 kDa heat shock protein, mitochondrial OS=Homo sapiens OX=9606 GN=HSPD1 PE=1 SV=2" 4.17 3718.2 - 730280 - - - 0.7737 - 3.036 0.377 - 124.3 1 1 0 0.0019 24 0 0 0 1.14E+07 9.16E+06 - - - 2.8633 1 221125_WJC_METTL3_EV_vs_WT_F04.23566.23566.3 4.25E-08 19/56 R.NLSTVMDEIHTVLKK.D sp|Q8IX12|CCAR1_HUMAN 1 1726.9288 6.01 55806 23566 3 1726.927195 576.6502 Cell division cycle and apoptosis regulator protein 1 OS=Homo sapiens OX=9606 GN=CCAR1 PE=1 SV=2 6.75 3718.6 - 920130 - - - -0.9039 - 3.31 0.557 - 379.1 1 2 0 -0.0016 15 0 0 0 4.29E+07 7.14E+06 - - - 7.8728 0.9993 221125_WJC_METTL3_EV_vs_WT_F04.23567.23567.3 0.0011 Sep-52 R.DK[136.11]WLAPDGLIFPDR[166.11].A "sp|Q99873|ANM1_HUMAN,tr|E9PQ98|E9PQ98_HUMAN,tr|E9PKG1|E9PKG1_HUMAN,tr|E9PNR9|E9PNR9_HUMAN,tr|H0YDE4|H0YDE4_HUMAN,tr|E9PIX6|E9PIX6_HUMAN" 6 1659.874 2.12 55807 23567 3 1659.874454 554.2986 Protein arginine N-methyltransferase 1 OS=Homo sapiens OX=9606 GN=PRMT1 PE=1 SV=3 4.43 3718.7 - 316742 - - - 0.2964 - 2.004 0.391 - 99.8 1 2 1 0.0005 14 0 0 0 1.93E+07 9.08E+06 - - - 4.7465 1 221125_WJC_METTL3_EV_vs_WT_F04.23571.23571.4 1.54E-06 Dec-84 R.NLSTVMDEIHTVLK[136.11]K[136.11].D sp|Q8IX12|CCAR1_HUMAN 1 1742.9572 4.19 55809 23571 4 1742.957333 436.7466 Cell division cycle and apoptosis regulator protein 1 OS=Homo sapiens OX=9606 GN=CCAR1 PE=1 SV=2 6.75 3719.2 - 434394 - - - 0.1016 - 2.2 0.498 - 124.8 1 2 0 0.0002 15 0 0 0 4.69E+07 1.12E+07 - - - 3.8427 1 221125_WJC_METTL3_EV_vs_WT_F04.23572.23572.3 1.23E-09 16/68 K.DKPTYDEIFYTLSPVNGK.L "sp|Q9H4M9|EHD1_HUMAN,tr|A0A024R571|A0A024R571_HUMAN" 2 2086.0259 1.38 55810 23572 3 2086.029804 696.3492 EH domain-containing protein 1 OS=Homo sapiens OX=9606 GN=EHD1 PE=1 SV=2 4.56 3719.3 - 1.81E+06 - - - 1.8773 - 3.122 0.633 - 315.9 1 2 0 0.0039 18 0 0 0 3.78E+07 2.73E+07 - - - 8.4312 0.9999 221125_WJC_METTL3_EV_vs_WT_F04.23573.23573.3 3.30E-06 17/68 K.DK[136.11]PTYDEIFYTLSPVNGK[136.11].L "sp|Q9H4M9|EHD1_HUMAN,tr|A0A024R571|A0A024R571_HUMAN" 2 2102.0543 1.38 55811 23573 3 2102.059741 701.692 EH domain-containing protein 1 OS=Homo sapiens OX=9606 GN=EHD1 PE=1 SV=2 4.56 3719.4 - 1.15E+06 - - - 2.5941 - 2.879 0.527 - 391.8 1 2 0 0.0055 18 0 0 0 3.78E+07 2.73E+07 - - - 7.0472 0.9997 221125_WJC_METTL3_EV_vs_WT_F04.23579.23579.3 0.00115 19/52 K.AFVDFLSDEIKEER.K sp|Q07021|C1QBP_HUMAN 1 1696.8308 1.23 55815 23579 3 1696.827571 566.6175 "Complement component 1 Q subcomponent-binding protein, mitochondrial OS=Homo sapiens OX=9606 GN=C1QBP PE=1 SV=1" 4.18 3720.1 - 892976 - - - -1.9124 - 2.549 0.449 - 399.8 1 2 1 -0.0032 14 0 0 0 2.55E+07 2.07E+07 - - - 6.0317 0.9998 221125_WJC_METTL3_EV_vs_WT_F04.23580.23580.3 1.93E-06 17/52 K.AFVDFLSDEIK[136.11]EER[166.11].K sp|Q07021|C1QBP_HUMAN 1 1714.8533 1.23 55816 23580 3 1714.84841 572.625 "Complement component 1 Q subcomponent-binding protein, mitochondrial OS=Homo sapiens OX=9606 GN=C1QBP PE=1 SV=1" 4.18 3720.3 - 891317 - - - -2.8434 - 3.144 0.55 - 332.9 1 2 1 -0.0049 14 0 0 0 2.55E+07 2.07E+07 - - - 7.7148 1 221125_WJC_METTL3_EV_vs_WT_F04.23581.23581.2 1.05E-06 24-Nov R.FSGSGSGTDFTLK.L "sp|A2NJV5|KV229_HUMAN,sp|A0A087WW87|KV240_HUMAN,sp|P06310|KV230_HUMAN,sp|A0A075B6S2|KVD29_HUMAN,sp|P01614|KVD40_HUMAN,sp|P01615|KVD28_HUMAN,sp|A0A075B6S6|KVD30_HUMAN,sp|A0A075B6P5|KV228_HUMAN,sp|A0A0A0MRZ7|KVD26_HUMAN" 9 1302.6092 35.1 55817 23581 2 1302.608834 652.3119 Immunoglobulin kappa variable 2-29 OS=Homo sapiens OX=9606 GN=IGKV2-29 PE=3 SV=2 5.84 3720.4 - 399683 - - - -0.2779 - 2.406 0.622 - 201.2 1 2 0 -0.0004 13 0 0 0 1.08E+07 3.09E+05 - - - 5.8883 1 221125_WJC_METTL3_EV_vs_WT_F04.23587.23587.3 2.10E-09 20/100 K.TAATVTSALQPPVLSLTQPTQVGVGK.Q "sp|O00268|TAF4_HUMAN,tr|A0A0G2JRY5|A0A0G2JRY5_HUMAN" 2 2563.4221 1.34 55819 23587 3 2563.4253 855.4813 Transcription initiation factor TFIID subunit 4 OS=Homo sapiens OX=9606 GN=TAF4 PE=1 SV=2 8.41 3721.2 - 1.86E+06 - - - 1.2413 - 3.298 0.584 - 319.5 1 2 0 0.0032 26 0 0 0 5.30E+07 3.96E+07 - - - 7.7955 1 221125_WJC_METTL3_EV_vs_WT_F04.23591.23591.3 1.44E-09 20/100 K.TAATVTSALQPPVLSLTQPTQVGVGK[136.11].Q "sp|O00268|TAF4_HUMAN,tr|A0A0G2JRY5|A0A0G2JRY5_HUMAN" 2 2571.4363 1.34 55820 23591 3 2571.43582 858.1527 Transcription initiation factor TFIID subunit 4 OS=Homo sapiens OX=9606 GN=TAF4 PE=1 SV=2 8.41 3721.6 - 988659 - - - -0.1937 - 3.524 0.608 - 300.8 1 2 0 -0.0005 26 0 0 0 5.30E+07 3.96E+07 - - - 8.2163 1 221125_WJC_METTL3_EV_vs_WT_F04.23592.23592.3 1.70E-09 18/84 K.DINAYNC[160.03]EEPTEKLPFPIIDDR.N sp|P30041|PRDX6_HUMAN 1 2648.2428 0.96 55821 23592 3 2648.236787 883.7549 Peroxiredoxin-6 OS=Homo sapiens OX=9606 GN=PRDX6 PE=1 SV=3 4.02 3721.7 - 881215 - - - -2.283 - 3.314 0.716 - 254.8 1 2 1 -0.006 22 0 0 0 2.65E+07 2.77E+07 - - - 9.3616 0.9977 221125_WJC_METTL3_EV_vs_WT_F04.23602.23602.4 0.000104 15/90 S.KGLAPDLPEDLYHLIK.K "sp|P62277|RS13_HUMAN,tr|J3KMX5|J3KMX5_HUMAN" 2 1821.0036 1.02 55829 23602 4 1821.00228 456.2582 40S ribosomal protein S13 OS=Homo sapiens OX=9606 GN=RPS13 PE=1 SV=2 5.38 3722.9 - 538366 - - - -0.7446 - 3.146 0.555 - 156.3 1 1 0 -0.0014 16 0 0 0 5.78E+06 5.67E+06 - - - 4.4601 1 221125_WJC_METTL3_EV_vs_WT_F04.23604.23604.3 8.30E-11 20/60 K.K[136.11]VSQEILELLNTTTAK[136.11].E "sp|Q86U44|MTA70_HUMAN,tr|H0YFV6|H0YFV6_HUMAN" 2 1803.0324 0.01 55830 23604 3 1803.028903 602.0181 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 6.14 3723.1 - 1.69E+07 - - - -1.9561 - 3.863 0.68 - 839.2 1 2 0 -0.0035 16 0 0 0 6.95E+06 6.21E+08 - - - 9.588 1 221125_WJC_METTL3_EV_vs_WT_F04.23607.23607.3 6.34E-08 21/84 K.DINAYNC[160.03]EEPTEK[136.11]LPFPIIDDR[166.11].N sp|P30041|PRDX6_HUMAN 1 2666.2653 0.96 55832 23607 3 2666.267432 889.7624 Peroxiredoxin-6 OS=Homo sapiens OX=9606 GN=PRDX6 PE=1 SV=3 4.02 3723.4 - 1.50E+06 - - - 0.7985 - 3.412 0.644 - 434.7 1 2 1 0.0021 22 0 0 0 2.65E+07 2.77E+07 - - - 8.6291 1 221125_WJC_METTL3_EV_vs_WT_F04.23611.23611.3 1.22E-14 27/96 A.TGGAVFGEEGLTLNLEDVQPHDLGK.V "sp|P10809|CH60_HUMAN,tr|A0A7I2V2X6|A0A7I2V2X6_HUMAN,tr|A0A7I2YQK6|A0A7I2YQK6_HUMAN,tr|A0A7I2V599|A0A7I2V599_HUMAN" 4 2595.2817 1.68 55834 23611 3 2595.287095 866.1012 "60 kDa heat shock protein, mitochondrial OS=Homo sapiens OX=9606 GN=HSPD1 PE=1 SV=2" 4.17 3723.9 - 2.14E+06 - - - 2.0938 - 4.216 0.634 - 677.5 1 1 0 0.0054 25 0 0 0 4.07E+07 2.42E+07 - - - 8.9173 0.9996 221125_WJC_METTL3_EV_vs_WT_F04.23613.23613.3 9.07E-06 Dec-80 R.AQLSDYSDIVTTLDLAPPTK[136.11]K[136.11].L sp|O60216|RAD21_HUMAN 1 2291.2231 0.79 55836 23613 3 2291.219807 764.7483 Double-strand-break repair protein rad21 homolog OS=Homo sapiens OX=9606 GN=RAD21 PE=1 SV=2 4.43 3724.1 - 1.67E+06 - - - -1.4564 - 2.195 0.346 - 103.9 1 2 0 -0.0033 21 0 0 0 1.81E+07 2.30E+07 - - - 4.2815 1 221125_WJC_METTL3_EV_vs_WT_F04.23614.23614.3 1.04E-07 22/64 K.HVINFDLPSDIEEYVHR.L "sp|O00571|DDX3X_HUMAN,sp|O15523|DDX3Y_HUMAN,tr|A0A2R8YFR4|A0A2R8YFR4_HUMAN,tr|A0A2R8YCW1|A0A2R8YCW1_HUMAN,tr|A0A2R8YDT5|A0A2R8YDT5_HUMAN,tr|A0A2R8Y645|A0A2R8Y645_HUMAN,tr|A0A2R8YF78|A0A2R8YF78_HUMAN,tr|A0A0D9SFB3|A0A0D9SFB3_HUMAN,tr|A0A2R8YFS5|A0A2R8YFS5_HUMAN,tr|A0A0D9SF53|A0A0D9SF53_HUMAN,tr|A0A087WVZ1|A0A087WVZ1_HUMAN,tr|A0A0J9YVQ7|A0A0J9YVQ7_HUMAN,tr|A0A2R8Y5G6|A0A2R8Y5G6_HUMAN,tr|A0A2R8Y7T2|A0A2R8Y7T2_HUMAN,tr|A0A0D9SG12|A0A0D9SG12_HUMAN,tr|F6S8Q4|F6S8Q4_HUMAN,tr|A0A2U3TZJ9|A0A2U3TZJ9_HUMAN,tr|A0A2R8Y4A4|A0A2R8Y4A4_HUMAN" 18 2082.0171 1.43 55837 23614 3 2082.025513 695.013 ATP-dependent RNA helicase DDX3X OS=Homo sapiens OX=9606 GN=DDX3X PE=1 SV=3 4.72 3724.2 - 981033 - - - 4.0629 - 3.841 0.593 - 908.6 1 2 0 0.0085 17 0 0 0 2.37E+07 1.65E+07 - - - 8.5487 1 221125_WJC_METTL3_EV_vs_WT_F04.23619.23619.4 3.32E-10 22/138 K.IQFHNVKPEYLDAYNSLTEAVLPK.L "sp|Q9BPW8|NIPS1_HUMAN,tr|H7C2U6|H7C2U6_HUMAN,tr|F8WCR5|F8WCR5_HUMAN" 3 2788.4436 1.51 55840 23619 4 2788.446722 698.1182 Protein NipSnap homolog 1 OS=Homo sapiens OX=9606 GN=NIPSNAP1 PE=1 SV=1 5.45 3724.8 - 2.70E+06 - - - 1.1261 - 3.57 0.558 - 249.5 1 2 0 0.0031 24 0 0 0 5.83E+07 3.86E+07 - - - 4.4904 1 221125_WJC_METTL3_EV_vs_WT_F04.23620.23620.3 2.35E-13 20/80 R.AQLSDYSDIVTTLDLAPPTKK.L sp|O60216|RAD21_HUMAN 1 2275.1947 0.83 55841 23620 3 2275.192607 759.4055 Double-strand-break repair protein rad21 homolog OS=Homo sapiens OX=9606 GN=RAD21 PE=1 SV=2 4.43 3724.9 - 1.20E+06 - - - -0.9393 - 3.008 0.638 - 318.2 1 2 0 -0.0021 21 0 0 0 1.91E+07 2.30E+07 - - - 8.2927 0.9998 221125_WJC_METTL3_EV_vs_WT_F04.23621.23621.4 5.13E-07 20/102 K.EVTWEVLEGEVEK[136.11]EALK[136.11]K[136.11].L sp|P05455|LA_HUMAN 1 2139.1526 0.39 55842 23621 4 2139.147826 535.7954 Lupus La protein OS=Homo sapiens OX=9606 GN=SSB PE=1 SV=2 4.48 3725 - 804015 - - - -2.2093 - 3.205 0.504 - 224.9 1 2 1 -0.0047 18 0 0 0 4.27E+06 1.09E+07 - - - 4.0105 1 221125_WJC_METTL3_EV_vs_WT_F04.23628.23628.4 0.00447 23/114 K.ISNIVHISNLVRPFTLGQLK.E "sp|Q9UKV3|ACINU_HUMAN,tr|G3V3B0|G3V3B0_HUMAN,tr|S4R3H4|S4R3H4_HUMAN,tr|E7EQT4|E7EQT4_HUMAN" 4 2248.3056 1.48 55847 23628 4 2248.30795 563.0837 Apoptotic chromatin condensation inducer in the nucleus OS=Homo sapiens OX=9606 GN=ACIN1 PE=1 SV=2 11 3725.9 - 1.06E+06 - - - 1.0577 - 3.919 0.485 - 357.4 1 2 0 0.0024 20 0 0 0 3.03E+07 2.05E+07 - - - 3.9034 1 221125_WJC_METTL3_EV_vs_WT_F04.23629.23629.4 4.83E-08 24/96 K.HVINFDLPSDIEEYVHR[166.11].L "sp|O00571|DDX3X_HUMAN,sp|O15523|DDX3Y_HUMAN,tr|A0A2R8YFR4|A0A2R8YFR4_HUMAN,tr|A0A2R8YCW1|A0A2R8YCW1_HUMAN,tr|A0A2R8YDT5|A0A2R8YDT5_HUMAN,tr|A0A2R8Y645|A0A2R8Y645_HUMAN,tr|A0A2R8YF78|A0A2R8YF78_HUMAN,tr|A0A0D9SFB3|A0A0D9SFB3_HUMAN,tr|A0A2R8YFS5|A0A2R8YFS5_HUMAN,tr|A0A0D9SF53|A0A0D9SF53_HUMAN,tr|A0A087WVZ1|A0A087WVZ1_HUMAN,tr|A0A0J9YVQ7|A0A0J9YVQ7_HUMAN,tr|A0A2R8Y5G6|A0A2R8Y5G6_HUMAN,tr|A0A2R8Y7T2|A0A2R8Y7T2_HUMAN,tr|A0A0D9SG12|A0A0D9SG12_HUMAN,tr|F6S8Q4|F6S8Q4_HUMAN,tr|A0A2U3TZJ9|A0A2U3TZJ9_HUMAN,tr|A0A2R8Y4A4|A0A2R8Y4A4_HUMAN" 18 2092.0253 1.27 55848 23629 4 2092.02406 524.0136 ATP-dependent RNA helicase DDX3X OS=Homo sapiens OX=9606 GN=DDX3X PE=1 SV=3 4.72 3726.1 - 976659 - - - -0.6042 - 3.883 0.59 - 746 1 2 0 -0.0013 17 0 0 0 1.92E+07 1.51E+07 - - - 4.832 1 221125_WJC_METTL3_EV_vs_WT_F04.23630.23630.2 3.23E-13 18/32 R.DINLQDEDWNEFNDINK.L "sp|Q6P2Q9|PRP8_HUMAN,tr|I3L0J9|I3L0J9_HUMAN" 2 2120.9287 3.02 55849 23630 2 2120.92568 1061.4716 Pre-mRNA-processing-splicing factor 8 OS=Homo sapiens OX=9606 GN=PRPF8 PE=1 SV=2 3.66 3726.2 - 812915 - - - -1.4206 - 3.561 0.698 - 764.4 1 2 0 -0.003 17 0 0 0 1.89E+07 6.24E+06 - - - 7.3179 0.9979 221125_WJC_METTL3_EV_vs_WT_F04.23636.23636.3 0.000813 16/80 R.NPPGFAFVEFEDPR[166.11]DAADAVR[166.11].E "sp|P84103|SRSF3_HUMAN,tr|A0A087X2D0|A0A087X2D0_HUMAN" 2 2339.1085 1.32 55853 23636 3 2339.110602 780.7101 Serine\arginine-rich splicing factor 3 OS=Homo sapiens OX=9606 GN=SRSF3 PE=1 SV=1 4.11 3726.9 - 1.15E+06 - - - 0.8773 - 1.889 0.345 - 161.6 1 2 1 0.0021 21 0 0 0 3.04E+07 2.30E+07 - - - 3.9107 0.9999 221125_WJC_METTL3_EV_vs_WT_F04.23637.23637.4 0.000634 29/162 R.GLGSELKDSIPVTELSASGPFESHDLLR.K sp|Q9Y244|POMP_HUMAN 1 2953.5033 2.12 55854 23637 4 2953.508365 739.3831 Proteasome maturation protein OS=Homo sapiens OX=9606 GN=POMP PE=1 SV=1 4.5 3727 - 1.07E+06 - - - 1.721 - 4.861 0.557 - 711.1 1 2 1 0.0051 28 0 0 0 1.13E+08 5.34E+07 - - - 4.5637 1 221125_WJC_METTL3_EV_vs_WT_F04.23639.23639.3 6.88E-08 34/116 K.SHLSTAGGLAVPSLPTAGPYYSPYALYGQR.L sp|Q9H7S9|ZN703_HUMAN 1 3093.556 12.95 55856 23639 3 3093.560868 1032.1926 Zinc finger protein 703 OS=Homo sapiens OX=9606 GN=ZNF703 PE=1 SV=1 8.18 3727.3 - 784295 - - - 1.5781 - 5.585 0.703 - 999.8 1 2 0 0.0049 30 0 0 0 1.02E+08 7.87E+06 - - - 10.3337 0.9987 221125_WJC_METTL3_EV_vs_WT_F04.23641.23641.3 0.000103 14/68 K.ELQNTVSQLLESEGWNR[166.11]R[166.11].N "sp|Q7L0Y3|TM10C_HUMAN,tr|C9JVB6|C9JVB6_HUMAN" 2 2178.0932 1.54 55858 23641 3 2178.103656 727.0384 tRNA methyltransferase 10 homolog C OS=Homo sapiens OX=9606 GN=TRMT10C PE=1 SV=2 4.79 3727.6 - 629803 - - - 4.7849 - 2.444 0.406 - 173.6 1 2 0 0.0104 18 0 0 0 1.58E+07 1.02E+07 - - - 5.2889 1 221125_WJC_METTL3_EV_vs_WT_F04.23642.23642.3 2.93E-06 19/72 R.R[166.11]QATTIIADNIIFLSDQTK[136.11].E sp|Q04837|SSBP_HUMAN 1 2165.1811 1.32 55859 23642 3 2165.179633 722.7343 "Single-stranded DNA-binding protein, mitochondrial OS=Homo sapiens OX=9606 GN=SSBP1 PE=1 SV=1" 5.96 3727.7 - 604035 - - - -0.6789 - 2.803 0.492 - 279.4 1 2 0 -0.0015 19 0 0 0 9.23E+07 7.01E+07 - - - 6.5571 1 221125_WJC_METTL3_EV_vs_WT_F04.23648.23648.3 2.34E-15 20/84 K.SHLFDGLDDDEPSLANGAFMPK.K "sp|P52948|NUP98_HUMAN,tr|A0A3B3ITD8|A0A3B3ITD8_HUMAN,tr|H0YEN4|H0YEN4_HUMAN,tr|H0YCR0|H0YCR0_HUMAN" 4 2375.074 2.43 55863 23648 3 2375.075829 792.6986 Nuclear pore complex protein Nup98-Nup96 OS=Homo sapiens OX=9606 GN=NUP98 PE=1 SV=4 4.03 3728.3 - 1.72E+06 - - - 0.7798 - 4.128 0.729 - 574.8 1 2 0 0.0019 22 0 0 0 2.38E+07 9.81E+06 - - - 10.0285 1 221125_WJC_METTL3_EV_vs_WT_F04.23652.23652.3 3.64E-15 23/88 K.TVEEVLGHFGVNESTGLSLEQVK.K "sp|P16615|AT2A2_HUMAN,tr|J3QSY6|J3QSY6_HUMAN" 2 2471.2544 0.43 55867 23652 3 2471.257335 824.7587 Sarcoplasmic\endoplasmic reticulum calcium ATPase 2 OS=Homo sapiens OX=9606 GN=ATP2A2 PE=1 SV=1 4.48 3728.8 - 1.61E+06 - - - 1.1941 - 4.39 0.612 - 331.9 1 2 0 0.003 23 0 0 0 7.09E+06 1.66E+07 - - - 8.8328 0.9999 221125_WJC_METTL3_EV_vs_WT_F04.23653.23653.3 9.09E-08 20/80 R.NPPGFAFVEFEDPRDAADAVR.E "sp|P84103|SRSF3_HUMAN,tr|A0A087X2D0|A0A087X2D0_HUMAN" 2 2319.092 1.33 55868 23653 3 2319.089997 774.0379 Serine\arginine-rich splicing factor 3 OS=Homo sapiens OX=9606 GN=SRSF3 PE=1 SV=1 4.11 3728.9 - 1.52E+06 - - - -0.868 - 2.836 0.529 - 242.4 1 2 1 -0.002 21 0 0 0 3.06E+07 2.30E+07 - - - 6.9364 1 221125_WJC_METTL3_EV_vs_WT_F04.23660.23660.3 5.84E-09 27/116 K.WLNDAENLSSDSSLSSPSALNSPGIEGLSR.R "sp|P14859|PO2F1_HUMAN,tr|A0A0C4DG88|A0A0C4DG88_HUMAN,tr|A0A0A0MT46|A0A0A0MT46_HUMAN" 3 3102.4742 2.55 55873 23660 3 3102.465188 1035.1653 "POU domain, class 2, transcription factor 1 OS=Homo sapiens OX=9606 GN=POU2F1 PE=1 SV=2" 3.92 3729.8 - 9.86E+06 - - - -2.8938 - 4.374 0.669 - 602.5 1 2 0 -0.009 30 0 0 0 9.76E+07 3.84E+07 - - - 9.3912 0.9271 221125_WJC_METTL3_EV_vs_WT_F04.23664.23664.3 2.66E-06 14/68 K.LQVDYTGLIQSYEQNETK[136.11].L "sp|Q15643|TRIPB_HUMAN,tr|H0YJ97|H0YJ97_HUMAN" 2 2136.0466 2.03 55877 23664 3 2137.034559 713.0228 Thyroid receptor-interacting protein 11 OS=Homo sapiens OX=9606 GN=TRIP11 PE=1 SV=3 4.14 3730.1 - 1.62E+06 - - - 462.5039 - 2.571 0.504 - 234 1 2 0 0.9879 18 0 0 0 7.45E+07 3.67E+07 - - - 6.2368 0.9999 221125_WJC_METTL3_EV_vs_WT_F04.23667.23667.3 6.33E-07 19/72 R.GIDIHGVPYVINVTLPDEK.Q "sp|Q92499|DDX1_HUMAN,tr|A0A7I2V2M5|A0A7I2V2M5_HUMAN,tr|A0A087X2G1|A0A087X2G1_HUMAN,tr|A0A7I2V430|A0A7I2V430_HUMAN,tr|A0A7I2V4F0|A0A7I2V4F0_HUMAN,tr|A0A087WZ71|A0A087WZ71_HUMAN" 6 2078.1048 2.6 55880 23667 3 2078.102168 693.7089 ATP-dependent RNA helicase DDX1 OS=Homo sapiens OX=9606 GN=DDX1 PE=1 SV=2 4.54 3730.5 - 1.11E+06 - - - -1.2699 - 3.136 0.392 - 396.8 1 2 0 -0.0026 19 0 0 0 1.32E+07 5.05E+06 - - - 5.7177 1 221125_WJC_METTL3_EV_vs_WT_F04.23669.23669.4 5.67E-08 19/96 K.HVINFDLPSDIEEYVHR.L "sp|O00571|DDX3X_HUMAN,sp|O15523|DDX3Y_HUMAN,tr|A0A2R8YFR4|A0A2R8YFR4_HUMAN,tr|A0A2R8YCW1|A0A2R8YCW1_HUMAN,tr|A0A2R8YDT5|A0A2R8YDT5_HUMAN,tr|A0A2R8Y645|A0A2R8Y645_HUMAN,tr|A0A2R8YF78|A0A2R8YF78_HUMAN,tr|A0A0D9SFB3|A0A0D9SFB3_HUMAN,tr|A0A2R8YFS5|A0A2R8YFS5_HUMAN,tr|A0A0D9SF53|A0A0D9SF53_HUMAN,tr|A0A087WVZ1|A0A087WVZ1_HUMAN,tr|A0A0J9YVQ7|A0A0J9YVQ7_HUMAN,tr|A0A2R8Y5G6|A0A2R8Y5G6_HUMAN,tr|A0A2R8Y7T2|A0A2R8Y7T2_HUMAN,tr|A0A0D9SG12|A0A0D9SG12_HUMAN,tr|F6S8Q4|F6S8Q4_HUMAN,tr|A0A2U3TZJ9|A0A2U3TZJ9_HUMAN,tr|A0A2R8Y4A4|A0A2R8Y4A4_HUMAN" 18 2082.0171 1.27 55882 23669 4 2082.014721 521.5115 ATP-dependent RNA helicase DDX3X OS=Homo sapiens OX=9606 GN=DDX3X PE=1 SV=3 4.72 3730.7 - 1.04E+06 - - - -1.1205 - 3.196 0.473 - 258.6 1 2 0 -0.0023 17 0 0 0 1.92E+07 1.51E+07 - - - 3.7458 1 221125_WJC_METTL3_EV_vs_WT_F04.23672.23672.3 7.45E-07 25/72 R.RQATTIIADNIIFLSDQTK.E sp|Q04837|SSBP_HUMAN 1 2147.1586 1.32 55883 23672 3 2147.157942 716.7268 "Single-stranded DNA-binding protein, mitochondrial OS=Homo sapiens OX=9606 GN=SSBP1 PE=1 SV=1" 5.96 3731.1 - 4.82E+06 - - - -0.3218 - 4.43 0.584 - 1145 1 2 0 -0.0007 19 0 0 0 9.24E+07 7.02E+07 - - - 8.7075 1 221125_WJC_METTL3_EV_vs_WT_F04.23674.23674.3 1.81E-12 30/116 K.WLNDAENLSSDSSLSSPSALNSPGIEGLSR[166.11].R "sp|P14859|PO2F1_HUMAN,tr|A0A0C4DG88|A0A0C4DG88_HUMAN,tr|A0A0A0MT46|A0A0A0MT46_HUMAN" 3 3112.4824 2.55 55885 23674 3 3113.472548 1038.5014 "POU domain, class 2, transcription factor 1 OS=Homo sapiens OX=9606 GN=POU2F1 PE=1 SV=2" 3.92 3731.3 - 3.88E+06 - - - 318.1101 - 4.545 0.719 - 670.9 1 2 0 0.9901 30 0 0 0 9.76E+07 3.84E+07 - - - 9.7651 0.9999 221125_WJC_METTL3_EV_vs_WT_F04.23676.23676.3 6.11E-07 18/64 K.VTLENFYSNLIAQHEER.E sp|Q15208|STK38_HUMAN 1 2062.012 3.99 55887 23676 3 2062.005583 688.3446 Serine\threonine-protein kinase 38 OS=Homo sapiens OX=9606 GN=STK38 PE=1 SV=1 4.75 3731.5 - 2.39E+06 - - - -3.097 - 3.372 0.54 - 435.4 1 2 0 -0.0064 17 0 0 0 1.40E+08 3.50E+07 - - - 7.6294 0.9997 221125_WJC_METTL3_EV_vs_WT_F04.23681.23681.3 2.88E-06 17/80 R.DK[136.11]LDGNELDLSLSDLNEVPVK[136.11].E "sp|Q96AG4|LRC59_HUMAN,tr|I3L223|I3L223_HUMAN" 2 2328.2031 1.55 55889 23681 3 2328.199618 777.075 Leucine-rich repeat-containing protein 59 OS=Homo sapiens OX=9606 GN=LRRC59 PE=1 SV=1 3.96 3732.1 - 3.34E+06 - - - -1.5115 - 3.147 0.404 - 162.7 1 2 1 -0.0035 21 0 0 0 2.68E+08 1.72E+08 - - - 5.7918 0.9999 221125_WJC_METTL3_EV_vs_WT_F04.23686.23686.3 0.0106 21/144 K.LYQSAGGMPGGMPGGFPGGGAPPSGGASSGPTIEEVD.- "sp|P11142|HSP7C_HUMAN,tr|E9PNE6|E9PNE6_HUMAN,tr|A8K7Q2|A8K7Q2_HUMAN,tr|E9PKE3|E9PKE3_HUMAN" 4 3345.4918 - 55892 23686 3 3345.48472 1116.1712 Heat shock cognate 71 kDa protein OS=Homo sapiens OX=9606 GN=HSPA8 PE=1 SV=1 3.88 3732.8 - 3.50E+06 - - - -2.1184 - 3.388 0.381 - 174.5 1 2 0 -0.0071 37 0 0 0 - - - - - 5.5931 1 221125_WJC_METTL3_EV_vs_WT_F04.23699.23699.3 3.29E-09 22/64 K.VTLENFYSNLIAQHEER[166.11].E sp|Q15208|STK38_HUMAN 1 2072.0202 3.99 55899 23699 3 2072.013914 691.6807 Serine\threonine-protein kinase 38 OS=Homo sapiens OX=9606 GN=STK38 PE=1 SV=1 4.75 3734.3 - 2.44E+06 - - - -3.0526 - 3.739 0.608 - 681.1 1 2 0 -0.0063 17 0 0 0 1.40E+08 3.50E+07 - - - 8.6486 1 221125_WJC_METTL3_EV_vs_WT_F04.23700.23700.2 2.06E-08 19/30 K.K[136.11]VSQEILELLNTTTAK[136.11].E "sp|Q86U44|MTA70_HUMAN,tr|H0YFV6|H0YFV6_HUMAN" 2 1803.0324 0.001 55900 23700 2 1803.028634 902.5235 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 6.14 3734.4 - 2.29E+06 - - - -2.1053 - 3.783 0.638 - 942.4 1 2 0 -0.0038 16 0 0 0 0.00E+00 3.90E+07 - - - 7.0232 0.9999 221125_WJC_METTL3_EV_vs_WT_F04.23701.23701.4 2.31E-07 30/162 R.GLGSELK[136.11]DSIPVTELSASGPFESHDLLR[166.11].K sp|Q9Y244|POMP_HUMAN 1 2971.5258 2.16 55901 23701 4 2971.523186 743.8887 Proteasome maturation protein OS=Homo sapiens OX=9606 GN=POMP PE=1 SV=1 4.5 3734.5 - 2.81E+06 - - - -0.8635 - 5.303 0.587 - 749.1 1 2 1 -0.0026 28 0 0 0 1.20E+08 5.57E+07 - - - 4.8525 1 221125_WJC_METTL3_EV_vs_WT_F04.23705.23705.2 5.86E-12 17/32 R.STGEAFVQFASQEIAEK.A "sp|P55795|HNRH2_HUMAN,sp|P31943|HNRH1_HUMAN,tr|E5RGH4|E5RGH4_HUMAN,tr|H0YB39|H0YB39_HUMAN,tr|E5RGV0|E5RGV0_HUMAN,tr|E9PCY7|E9PCY7_HUMAN,tr|D6RIU0|D6RIU0_HUMAN,tr|D6RBM0|D6RBM0_HUMAN,tr|G8JLB6|G8JLB6_HUMAN,tr|E7EN40|E7EN40_HUMAN" 10 1840.8843 0.3 55903 23705 2 1840.878262 921.4494 Heterogeneous nuclear ribonucleoprotein H2 OS=Homo sapiens OX=9606 GN=HNRNPH2 PE=1 SV=1 4.25 3735.1 - 2.28E+06 - - - -3.2848 - 3.455 0.641 - 1134.2 1 2 0 -0.006 17 0 0 0 8.19E+07 2.70E+08 - - - 6.8217 1 221125_WJC_METTL3_EV_vs_WT_F04.23711.23711.2 8.20E-13 18/32 R.STGEAFVQFASQEIAEK[136.11].A "sp|P55795|HNRH2_HUMAN,sp|P31943|HNRH1_HUMAN,tr|E5RGH4|E5RGH4_HUMAN,tr|H0YB39|H0YB39_HUMAN,tr|E5RGV0|E5RGV0_HUMAN,tr|E9PCY7|E9PCY7_HUMAN,tr|D6RIU0|D6RIU0_HUMAN,tr|D6RBM0|D6RBM0_HUMAN,tr|G8JLB6|G8JLB6_HUMAN,tr|E7EN40|E7EN40_HUMAN" 10 1848.8985 0.28 55906 23711 2 1848.895424 925.4565 Heterogeneous nuclear ribonucleoprotein H2 OS=Homo sapiens OX=9606 GN=HNRNPH2 PE=1 SV=1 4.25 3735.7 - 2.97E+06 - - - -1.6686 - 3.581 0.67 - 1410.2 1 2 0 -0.0031 17 0 0 0 8.20E+07 2.90E+08 - - - 7.1249 0.9996 221125_WJC_METTL3_EV_vs_WT_F04.23712.23712.4 6.33E-07 17/108 K.SAEKEISLWFKPEELVDYK.S "sp|P22392|NDKB_HUMAN,tr|Q32Q12|Q32Q12_HUMAN" 2 2310.1784 1.55 55907 23712 4 2310.171989 578.5519 Nucleoside diphosphate kinase B OS=Homo sapiens OX=9606 GN=NME2 PE=1 SV=1 4.58 3735.8 - 2.35E+06 - - - -2.76 - 3.419 0.49 - 193.4 1 2 1 -0.0064 19 0 0 0 3.11E+07 2.00E+07 - - - 3.9051 1 221125_WJC_METTL3_EV_vs_WT_F04.23713.23713.3 7.55E-21 35/108 K.LQEQHLSSPQGVQLDIASQSLDQEILLK.V "sp|Q9BXK5|B2L13_HUMAN,tr|A0A0A0MR90|A0A0A0MR90_HUMAN,tr|F2Z2C3|F2Z2C3_HUMAN,tr|E9PDD6|E9PDD6_HUMAN,tr|A0A087WW80|A0A087WW80_HUMAN" 5 3116.6354 1.8 55908 23713 3 3116.629962 1039.8857 Bcl-2-like protein 13 OS=Homo sapiens OX=9606 GN=BCL2L13 PE=1 SV=1 4.31 3735.9 - 2.29E+06 - - - -1.7314 - 6.663 0.737 - 1966.4 1 2 0 -0.0054 28 0 0 0 2.70E+07 1.50E+07 - - - 11.1186 1 221125_WJC_METTL3_EV_vs_WT_F04.23719.23719.3 8.76E-07 14/64 R.STGEAFVQFASQEIAEK[136.11].A "sp|P55795|HNRH2_HUMAN,sp|P31943|HNRH1_HUMAN,tr|E5RGH4|E5RGH4_HUMAN,tr|H0YB39|H0YB39_HUMAN,tr|E5RGV0|E5RGV0_HUMAN,tr|E9PCY7|E9PCY7_HUMAN,tr|D6RIU0|D6RIU0_HUMAN,tr|D6RBM0|D6RBM0_HUMAN,tr|G8JLB6|G8JLB6_HUMAN,tr|E7EN40|E7EN40_HUMAN" 10 1848.8985 0.53 55912 23719 3 1848.896994 617.3068 Heterogeneous nuclear ribonucleoprotein H2 OS=Homo sapiens OX=9606 GN=HNRNPH2 PE=1 SV=1 4.25 3736.7 - 2.13E+06 - - - -0.8194 - 2.711 0.589 - 257.8 1 2 0 -0.0015 17 0 0 0 3.83E+07 7.24E+07 - - - 7.6259 1 221125_WJC_METTL3_EV_vs_WT_F04.23720.23720.3 8.98E-07 17/64 R.STGEAFVQFASQEIAEK.A "sp|P55795|HNRH2_HUMAN,sp|P31943|HNRH1_HUMAN,tr|E5RGH4|E5RGH4_HUMAN,tr|H0YB39|H0YB39_HUMAN,tr|E5RGV0|E5RGV0_HUMAN,tr|E9PCY7|E9PCY7_HUMAN,tr|D6RIU0|D6RIU0_HUMAN,tr|D6RBM0|D6RBM0_HUMAN,tr|G8JLB6|G8JLB6_HUMAN,tr|E7EN40|E7EN40_HUMAN" 10 1840.8843 0.55 55913 23720 3 1840.885042 614.6354 Heterogeneous nuclear ribonucleoprotein H2 OS=Homo sapiens OX=9606 GN=HNRNPH2 PE=1 SV=1 4.25 3736.8 - 2.48E+06 - - - 0.3982 - 2.782 0.49 - 200.2 1 2 0 0.0007 17 0 0 0 3.82E+07 6.97E+07 - - - 6.5876 1 221125_WJC_METTL3_EV_vs_WT_F04.23727.23727.3 9.03E-07 20/72 K.ILTATVDNANVLLQIDNAR.L sp|P02533|K1C14_HUMAN 1 2053.1168 999 55918 23727 3 2053.116175 685.3795 "Keratin, type I cytoskeletal 14 OS=Homo sapiens OX=9606 GN=KRT14 PE=1 SV=4" 4.21 3737.7 - 1.40E+06 - - - -0.2888 - 3.538 0.565 - 489.9 1 2 0 -0.0006 19 0 0 0 1.82E+07 0.00E+00 - - - 7.9433 1 221125_WJC_METTL3_EV_vs_WT_F04.23728.23728.3 3.68E-07 25/96 R.QTVADQVLVGSYC[160.03]VFSNQGGLVHPK.T sp|P56537|IF6_HUMAN 1 2702.3486 1.59 55919 23728 3 2702.347972 901.7902 Eukaryotic translation initiation factor 6 OS=Homo sapiens OX=9606 GN=EIF6 PE=1 SV=1 6.73 3737.8 - 2.30E+06 - - - -0.2457 - 3.823 0.627 - 395.4 1 2 0 -0.0007 25 0 0 0 4.58E+07 2.88E+07 - - - 8.6155 0.9998 221125_WJC_METTL3_EV_vs_WT_F04.23734.23734.4 3.67E-07 19/108 K.SAEK[136.11]EISLWFK[136.11]PEELVDYK[136.11].S "sp|P22392|NDKB_HUMAN,tr|Q32Q12|Q32Q12_HUMAN" 2 2334.221 1.55 55923 23734 4 2334.219513 584.5625 Nucleoside diphosphate kinase B OS=Homo sapiens OX=9606 GN=NME2 PE=1 SV=1 4.58 3738.5 - 910028 - - - -0.622 - 3.046 0.475 - 263.5 1 2 1 -0.0015 19 0 0 0 3.11E+07 2.00E+07 - - - 3.7368 1 221125_WJC_METTL3_EV_vs_WT_F04.23736.23736.3 1.61E-11 24/96 R.QTVADQVLVGSYC[160.03]VFSNQGGLVHPK[136.11].T sp|P56537|IF6_HUMAN 1 2710.3628 1.59 55925 23736 3 2710.360933 904.4616 Eukaryotic translation initiation factor 6 OS=Homo sapiens OX=9606 GN=EIF6 PE=1 SV=1 6.73 3738.8 - 2.01E+06 - - - -0.7021 - 3.956 0.644 - 541.6 1 2 0 -0.0019 25 0 0 0 4.58E+07 2.88E+07 - - - 8.8834 1 221125_WJC_METTL3_EV_vs_WT_F04.23737.23737.4 2.25E-10 30/192 K.IEPAQAVDEVEPLPEDYYTRPVNLTEVTTLQQR.L sp|Q9UJW0|DCTN4_HUMAN 1 3812.9109 1.33 55926 23737 4 3812.912021 954.235 Dynactin subunit 4 OS=Homo sapiens OX=9606 GN=DCTN4 PE=1 SV=1 4 3738.9 - 1.18E+06 - - - 0.3032 - 3.989 0.627 - 339.1 1 2 0 0.0012 33 0 0 0 8.06E+06 6.07E+06 - - - 5.0982 1 221125_WJC_METTL3_EV_vs_WT_F04.23740.23740.3 2.31E-10 17/68 K.AHVLAASVEQATENFLEK.G "sp|P35221|CTNA1_HUMAN,tr|E5RHV7|E5RHV7_HUMAN,tr|E5RJL0|E5RJL0_HUMAN,tr|E5RIE0|E5RIE0_HUMAN,tr|E5RIB1|E5RIB1_HUMAN,tr|E5RGY6|E5RGY6_HUMAN,tr|E5RG03|E5RG03_HUMAN,tr|E5RFM3|E5RFM3_HUMAN,tr|G3XAM7|G3XAM7_HUMAN" 9 1955.9953 2.08 55929 23740 3 1955.995241 653.0057 Catenin alpha-1 OS=Homo sapiens OX=9606 GN=CTNNA1 PE=1 SV=1 4.75 3739.3 - 584828 - - - -0.0077 - 3.559 0.594 - 493.3 1 2 0 0 18 0 0 0 1.06E+07 5.09E+06 - - - 8.3236 1 221125_WJC_METTL3_EV_vs_WT_F04.23744.23744.4 6.18E-10 25/162 R.TVSLGAGAKDELHIVEAEAMNYEGSPIK.V "sp|P06748|NPM_HUMAN,tr|A0A7I2V4G8|A0A7I2V4G8_HUMAN,tr|A0A7I2YQC0|A0A7I2YQC0_HUMAN,tr|A0A7I2V433|A0A7I2V433_HUMAN,tr|A0A7I2V579|A0A7I2V579_HUMAN,tr|A0A7I2V2X9|A0A7I2V2X9_HUMAN,tr|A0A7I2V3G5|A0A7I2V3G5_HUMAN,tr|A0A7I2V5S2|A0A7I2V5S2_HUMAN,tr|A0A7I2V3U2|A0A7I2V3U2_HUMAN" 9 2928.4539 1.17 55931 23744 4 2928.463881 733.1207 Nucleophosmin OS=Homo sapiens OX=9606 GN=NPM1 PE=1 SV=2 4.57 3739.8 - 2.79E+06 - - - 3.412 - 4.696 0.614 - 461.9 1 2 1 0.01 28 0 0 0 6.77E+07 5.79E+07 - - - 5.0477 0.9999 221125_WJC_METTL3_EV_vs_WT_F04.23747.23747.3 1.77E-08 25/80 K.QNLSKEELIAELQDC[160.03]EGLIVR.S "sp|O43175|SERA_HUMAN,tr|A0A2C9F2M7|A0A2C9F2M7_HUMAN,tr|A0A286YFB2|A0A286YFB2_HUMAN,tr|A0A286YF34|A0A286YF34_HUMAN,tr|A0A286YFC8|A0A286YFC8_HUMAN,tr|A0A286YF22|A0A286YF22_HUMAN,tr|A0A286YFL2|A0A286YFL2_HUMAN,tr|A0A286YFA2|A0A286YFA2_HUMAN,tr|A0A286YFM8|A0A286YFM8_HUMAN,tr|A0A286YER3|A0A286YER3_HUMAN" 10 2456.2581 1.09 55934 23747 3 2456.261508 819.76 D-3-phosphoglycerate dehydrogenase OS=Homo sapiens OX=9606 GN=PHGDH PE=1 SV=4 4.25 3740.1 - 814281 - - - 1.392 - 4.186 0.578 - 788.6 1 2 1 0.0034 21 0 0 0 1.67E+07 1.53E+07 - - - 8.4157 1 221125_WJC_METTL3_EV_vs_WT_F04.23749.23749.4 3.11E-11 20/108 K.NQLNPIGSLQELAIHHGWR.L "sp|O75569|PRKRA_HUMAN,tr|B4DJC7|B4DJC7_HUMAN,tr|A0A7I2V3J2|A0A7I2V3J2_HUMAN,tr|A0A7I2V2I8|A0A7I2V2I8_HUMAN,tr|A0A7I2V5H3|A0A7I2V5H3_HUMAN,tr|A0A7I2YQ87|A0A7I2YQ87_HUMAN" 6 2182.1396 1.53 55936 23749 4 2182.139782 546.5422 Interferon-inducible double-stranded RNA-dependent protein kinase activator A OS=Homo sapiens OX=9606 GN=PRKRA PE=1 SV=1 6.92 3740.4 - 450938 - - - 0.0976 - 3.718 0.616 - 407.3 1 2 0 0.0002 19 0 0 0 1.31E+07 8.60E+06 - - - 5.0318 0.9984 221125_WJC_METTL3_EV_vs_WT_F04.23754.23754.2 0.156 18-Aug K.ILLAELEQLK[136.11].G "sp|P08670|VIME_HUMAN,tr|B0YJC4|B0YJC4_HUMAN,tr|A0A1B0GTT5|A0A1B0GTT5_HUMAN" 3 1176.7209 2.04 55939 23754 2 1176.721427 589.3677 Vimentin OS=Homo sapiens OX=9606 GN=VIM PE=1 SV=4 4.53 3741 - 310360 - - - 0.4266 - 1.598 0.225 - 109.5 1 2 0 0.0005 10 0 0 0 9.27E+06 4.55E+06 - - - 2.0111 1 221125_WJC_METTL3_EV_vs_WT_F04.23756.23756.4 1.23E-05 18/90 K.GLAPDLPEDLYHLIK[136.11]K[136.11].A "sp|P62277|RS13_HUMAN,tr|J3KMX5|J3KMX5_HUMAN" 2 1837.032 1.06 55941 23756 4 1837.032993 460.2653 40S ribosomal protein S13 OS=Homo sapiens OX=9606 GN=RPS13 PE=1 SV=2 5.38 3741.2 - 742197 - - - 0.5209 - 3.156 0.53 - 219.3 1 2 0 0.001 16 0 0 0 4.08E+07 3.86E+07 - - - 4.2437 0.9999 221125_WJC_METTL3_EV_vs_WT_F04.23759.23759.3 0.00165 Oct-60 R.SDATADDLIDVVEGNR.V sp|Q9Y295|DRG1_HUMAN 1 1688.7853 0.35 55944 23759 3 1688.785656 563.9357 Developmentally-regulated GTP-binding protein 1 OS=Homo sapiens OX=9606 GN=DRG1 PE=1 SV=1 3.71 3741.6 - 292988 - - - 0.1972 - 1.907 0.415 - 100.8 1 2 0 0.0003 16 0 0 0 6.86E+06 1.97E+07 - - - 4.8231 1 221125_WJC_METTL3_EV_vs_WT_F04.23762.23762.3 1.71E-09 24/68 K.R[166.11]QAFTPSSTMMEVFLQEK[136.11].S "sp|Q14157|UBP2L_HUMAN,tr|F8W726|F8W726_HUMAN" 2 2147.051 3.26 55945 23762 3 2147.054095 716.6909 Ubiquitin-associated protein 2-like OS=Homo sapiens OX=9606 GN=UBAP2L PE=1 SV=2 6.14 3742 - 1.70E+06 - - - 1.4336 - 4.156 0.621 - 871.2 1 2 0 0.0031 18 0 0 0 5.40E+07 1.66E+07 - - - 9.01 1 221125_WJC_METTL3_EV_vs_WT_F04.23765.23765.3 1.27E-13 29/108 R.TVSLGAGAKDELHIVEAEAMNYEGSPIK.V "sp|P06748|NPM_HUMAN,tr|A0A7I2V4G8|A0A7I2V4G8_HUMAN,tr|A0A7I2YQC0|A0A7I2YQC0_HUMAN,tr|A0A7I2V433|A0A7I2V433_HUMAN,tr|A0A7I2V579|A0A7I2V579_HUMAN,tr|A0A7I2V2X9|A0A7I2V2X9_HUMAN,tr|A0A7I2V3G5|A0A7I2V3G5_HUMAN,tr|A0A7I2V5S2|A0A7I2V5S2_HUMAN,tr|A0A7I2V3U2|A0A7I2V3U2_HUMAN" 9 2928.4539 0.8 55948 23765 3 2928.456774 977.1586 Nucleophosmin OS=Homo sapiens OX=9606 GN=NPM1 PE=1 SV=2 4.57 3742.3 - 914903 - - - 0.9852 - 5.261 0.718 - 1122.8 1 2 1 0.0029 28 0 0 0 9.89E+06 1.24E+07 - - - 10.364 1 221125_WJC_METTL3_EV_vs_WT_F04.23766.23766.3 3.42E-09 15/72 R.YEGILYTIDTENSTVALAK.V "sp|Q8ND56|LS14A_HUMAN,tr|I3L4Q1|I3L4Q1_HUMAN,tr|A0A140TA76|A0A140TA76_HUMAN,tr|K7EMZ9|K7EMZ9_HUMAN" 4 2100.0627 0.16 55949 23766 3 2100.063106 701.0282 Protein LSM14 homolog A OS=Homo sapiens OX=9606 GN=LSM14A PE=1 SV=3 4.14 3742.4 - 894622 - - - 0.209 - 3.371 0.56 - 339.8 1 2 0 0.0004 19 0 0 0 8.61E+06 5.36E+07 - - - 7.7689 1 221125_WJC_METTL3_EV_vs_WT_F04.23767.23767.3 7.95E-17 28/108 R.TVSLGAGAK[136.11]DELHIVEAEAMNYEGSPIK[136.11].V "sp|P06748|NPM_HUMAN,tr|A0A7I2V4G8|A0A7I2V4G8_HUMAN,tr|A0A7I2YQC0|A0A7I2YQC0_HUMAN,tr|A0A7I2V433|A0A7I2V433_HUMAN,tr|A0A7I2V579|A0A7I2V579_HUMAN,tr|A0A7I2V2X9|A0A7I2V2X9_HUMAN,tr|A0A7I2V3G5|A0A7I2V3G5_HUMAN,tr|A0A7I2V5S2|A0A7I2V5S2_HUMAN,tr|A0A7I2V3U2|A0A7I2V3U2_HUMAN" 9 2944.4823 0.8 55950 23767 3 2944.487774 982.5014 Nucleophosmin OS=Homo sapiens OX=9606 GN=NPM1 PE=1 SV=2 4.57 3742.6 - 818299 - - - 1.8628 - 5.093 0.682 - 849.9 1 2 1 0.0055 28 0 0 0 9.89E+06 1.24E+07 - - - 9.8872 0.9999 221125_WJC_METTL3_EV_vs_WT_F04.23769.23769.4 0.00019 15/144 R.QTVADQVLVGSYC[160.03]VFSNQGGLVHPK[136.11].T sp|P56537|IF6_HUMAN 1 2710.3628 1.62 55952 23769 4 2710.364765 678.598 Eukaryotic translation initiation factor 6 OS=Homo sapiens OX=9606 GN=EIF6 PE=1 SV=1 6.73 3742.8 - 576807 - - - 0.7117 - 2.844 0.428 - 167.9 1 2 0 0.0019 25 0 0 0 1.08E+07 6.68E+06 - - - 3.2833 1 221125_WJC_METTL3_EV_vs_WT_F04.23770.23770.2 3.29E-11 18/36 R.AEDNADTLALVFEAPNQEK[136.11].V sp|P12004|PCNA_HUMAN 1 2081.9997 0.03 55953 23770 2 2081.999749 1042.0071 Proliferating cell nuclear antigen OS=Homo sapiens OX=9606 GN=PCNA PE=1 SV=1 3.83 3743 - 297552 - - - 0.0336 - 3.461 0.709 - 654.2 1 2 0 0.0001 19 0 0 0 3.52E+05 1.07E+07 - - - 7.3301 0.9999 221125_WJC_METTL3_EV_vs_WT_F04.23775.23775.3 6.28E-06 13/60 K.GLAPDLPEDLYHLIKK.A "sp|P62277|RS13_HUMAN,tr|J3KMX5|J3KMX5_HUMAN" 2 1821.0036 1.06 55956 23775 3 1821.0075 608.0085 40S ribosomal protein S13 OS=Homo sapiens OX=9606 GN=RPS13 PE=1 SV=2 5.38 3743.5 - 578631 - - - 2.1219 - 2.679 0.505 - 177.4 1 2 0 0.0039 16 0 0 0 1.70E+07 1.60E+07 - - - 6.6977 0.9995 221125_WJC_METTL3_EV_vs_WT_F04.23777.23777.3 0.0503 13/72 R.YEGILYTIDTENSTVALAK[136.11].V "sp|Q8ND56|LS14A_HUMAN,tr|I3L4Q1|I3L4Q1_HUMAN,tr|A0A140TA76|A0A140TA76_HUMAN,tr|K7EMZ9|K7EMZ9_HUMAN" 4 2108.0769 0.17 55958 23777 3 2108.073859 703.6996 Protein LSM14 homolog A OS=Homo sapiens OX=9606 GN=LSM14A PE=1 SV=3 4.14 3743.7 - 2.40E+06 - - - -1.4269 - 2.149 0.32 - 113.2 1 2 0 -0.003 19 0 0 0 8.96E+06 5.36E+07 - - - 3.9863 1 221125_WJC_METTL3_EV_vs_WT_F04.23778.23778.4 8.41E-13 24/138 R.YQQQYLQPLPLTHYELVTDAFGHR.A "sp|Q96T37|RBM15_HUMAN,tr|A0A494C001|A0A494C001_HUMAN,tr|A0A499FJY3|A0A499FJY3_HUMAN,tr|A0A087WWP4|A0A087WWP4_HUMAN" 4 2916.4559 0.3 55959 23778 4 2916.460984 730.1212 RNA-binding protein 15 OS=Homo sapiens OX=9606 GN=RBM15 PE=1 SV=2 5.99 3743.8 - 1.05E+06 - - - 1.7508 - 4.433 0.661 - 425.6 1 2 0 0.0051 24 0 0 0 1.88E+07 6.34E+07 - - - 5.4559 1 221125_WJC_METTL3_EV_vs_WT_F04.23779.23779.3 2.75E-13 23/76 R.ISLGLPVGAVINC[160.03]ADNTGAK[136.11].N "sp|P62829|RL23_HUMAN,tr|J3KT29|J3KT29_HUMAN,tr|B9ZVP7|B9ZVP7_HUMAN,tr|C9JD32|C9JD32_HUMAN" 4 1977.0445 1.09 55960 23779 3 1977.048445 660.0221 60S ribosomal protein L23 OS=Homo sapiens OX=9606 GN=RPL23 PE=1 SV=1 5.83 3743.9 - 892725 - - - 2.0146 - 4.095 0.666 - 683.8 1 2 0 0.004 20 0 0 0 5.43E+07 4.96E+07 - - - 9.3843 1 221125_WJC_METTL3_EV_vs_WT_F04.23780.23780.2 5.85E-12 21/38 R.ISLGLPVGAVINC[160.03]ADNTGAK.N "sp|P62829|RL23_HUMAN,tr|J3KT29|J3KT29_HUMAN,tr|B9ZVP7|B9ZVP7_HUMAN,tr|C9JD32|C9JD32_HUMAN" 4 1969.0303 1.17 55961 23780 2 1969.034862 985.5224 60S ribosomal protein L23 OS=Homo sapiens OX=9606 GN=RPL23 PE=1 SV=1 5.83 3744.1 - 859917 - - - 2.3362 - 3.481 0.702 - 1100.6 1 2 0 0.0046 20 0 0 0 4.90E+07 4.18E+07 - - - 7.2911 1 221125_WJC_METTL3_EV_vs_WT_F04.23781.23781.3 3.26E-12 17/84 K.IESDVQEPTEPEDDLDIMLGNK.K sp|P20042|IF2B_HUMAN 1 2486.137 0.96 55962 23781 3 2486.142356 829.7196 Eukaryotic translation initiation factor 2 subunit 2 OS=Homo sapiens OX=9606 GN=EIF2S2 PE=1 SV=2 3.58 3744.2 - 554382 - - - 2.1419 - 3.607 0.644 - 297.7 1 2 0 0.0053 22 0 0 0 1.24E+07 1.29E+07 - - - 8.76 1 221125_WJC_METTL3_EV_vs_WT_F04.23782.23782.3 2.66E-11 20/92 K.LNSNTQVVLLSATMPSDVLEVTK[136.11]K[136.11].F "sp|P60842|IF4A1_HUMAN,tr|J3KTB5|J3KTB5_HUMAN,tr|J3KT12|J3KT12_HUMAN,tr|J3QS69|J3QS69_HUMAN,tr|J3KTN0|J3KTN0_HUMAN,tr|J3KSZ0|J3KSZ0_HUMAN" 6 2602.4223 0.85 55963 23782 3 2602.425415 868.4814 Eukaryotic initiation factor 4A-I OS=Homo sapiens OX=9606 GN=EIF4A1 PE=1 SV=1 6.07 3744.3 - 549319 - - - 1.2146 - 4.396 0.531 - 276.7 1 2 0 0.0032 24 0 0 0 9.91E+06 1.16E+07 - - - 7.8983 1 221125_WJC_METTL3_EV_vs_WT_F04.23783.23783.2 1.18E-09 21/38 R.ISLGLPVGAVINC[160.03]ADNTGAK[136.11].N "sp|P62829|RL23_HUMAN,tr|J3KT29|J3KT29_HUMAN,tr|B9ZVP7|B9ZVP7_HUMAN,tr|C9JD32|C9JD32_HUMAN" 4 1977.0445 1.17 55964 23783 2 1977.042672 989.5295 60S ribosomal protein L23 OS=Homo sapiens OX=9606 GN=RPL23 PE=1 SV=1 5.83 3744.4 - 540242 - - - -0.9054 - 3.369 0.654 - 1020.2 1 2 0 -0.0018 20 0 0 0 4.90E+07 4.18E+07 - - - 6.8571 1 221125_WJC_METTL3_EV_vs_WT_F04.23787.23787.3 3.98E-11 17/64 R.QEIEC[160.03]QNQEYSLLLSIK.M "sp|P35527|K1C9_HUMAN,tr|K7EQQ3|K7EQQ3_HUMAN" 2 2094.0303 83.02 55966 23787 3 2094.034046 699.0174 "Keratin, type I cytoskeletal 9 OS=Homo sapiens OX=9606 GN=KRT9 PE=1 SV=3" 4.25 3745 - 2.73E+06 - - - 1.7789 - 3.354 0.561 - 486.3 1 2 0 0.0037 17 0 0 0 5.01E+07 6.03E+05 - - - 7.8508 1 221125_WJC_METTL3_EV_vs_WT_F04.23789.23789.3 3.33E-13 24/76 R.ISLGLPVGAVINC[160.03]ADNTGAK.N "sp|P62829|RL23_HUMAN,tr|J3KT29|J3KT29_HUMAN,tr|B9ZVP7|B9ZVP7_HUMAN,tr|C9JD32|C9JD32_HUMAN" 4 1969.0303 1.09 55968 23789 3 1969.033216 657.3507 60S ribosomal protein L23 OS=Homo sapiens OX=9606 GN=RPL23 PE=1 SV=1 5.83 3745.2 - 2.87E+06 - - - 1.5002 - 3.839 0.717 - 840.2 1 2 0 0.003 20 0 0 0 5.43E+07 4.96E+07 - - - 9.7965 0.9999 221125_WJC_METTL3_EV_vs_WT_F04.23790.23790.3 8.16E-08 16/72 R.DSQLYAVDYETLTRPFSGR.R "sp|P82930|RT34_HUMAN,tr|C9JJ19|C9JJ19_HUMAN" 2 2217.0702 0.95 55969 23790 3 2217.073307 740.0307 "28S ribosomal protein S34, mitochondrial OS=Homo sapiens OX=9606 GN=MRPS34 PE=1 SV=2" 4.56 3745.3 - 1.88E+06 - - - 1.396 - 3.014 0.384 - 308.4 1 2 0 0.0031 19 0 0 0 2.58E+07 2.73E+07 - - - 5.5309 1 221125_WJC_METTL3_EV_vs_WT_F04.23792.23792.2 5.92E-09 16/32 R.QEIEC[160.03]QNQEYSLLLSIK.M "sp|P35527|K1C9_HUMAN,tr|K7EQQ3|K7EQQ3_HUMAN" 2 2094.0303 999 55971 23792 2 2094.033074 1048.0224 "Keratin, type I cytoskeletal 9 OS=Homo sapiens OX=9606 GN=KRT9 PE=1 SV=3" 4.25 3745.5 - 1.02E+06 - - - 1.3147 - 3.723 0.649 - 830.6 1 2 0 0.0028 17 0 0 0 2.25E+07 0.00E+00 - - - 7.0655 1 221125_WJC_METTL3_EV_vs_WT_F04.23793.23793.3 3.54E-11 25/92 K.LNSNTQVVLLSATMPSDVLEVTKK.F "sp|P60842|IF4A1_HUMAN,tr|J3KTB5|J3KTB5_HUMAN,tr|J3KT12|J3KT12_HUMAN,tr|J3QS69|J3QS69_HUMAN,tr|J3KTN0|J3KTN0_HUMAN,tr|J3KSZ0|J3KSZ0_HUMAN" 6 2586.3939 0.85 55972 23793 3 2586.402417 863.1386 Eukaryotic initiation factor 4A-I OS=Homo sapiens OX=9606 GN=EIF4A1 PE=1 SV=1 6.07 3745.6 - 725865 - - - 3.3108 - 5.027 0.643 - 473.6 1 2 0 0.0086 24 0 0 0 9.91E+06 1.16E+07 - - - 9.457 0.9929 221125_WJC_METTL3_EV_vs_WT_F04.23796.23796.4 0.0189 14/114 K.TKDLPVTEAVFSALVTGHAR.A "sp|P42704|LPPRC_HUMAN,tr|A0A804HI14|A0A804HI14_HUMAN,tr|A0A804HL40|A0A804HL40_HUMAN,tr|A0A804HKJ0|A0A804HKJ0_HUMAN,tr|A0A804HKR3|A0A804HKR3_HUMAN,tr|A0A0C4DG06|A0A0C4DG06_HUMAN,tr|A0A804HIN4|A0A804HIN4_HUMAN,tr|A0A804HLG8|A0A804HLG8_HUMAN,tr|A0A804HIV5|A0A804HIV5_HUMAN,tr|A0A804HHY9|A0A804HHY9_HUMAN,tr|A0A804HJH8|A0A804HJH8_HUMAN,tr|B8ZZ38|B8ZZ38_HUMAN,tr|A0A804HI40|A0A804HI40_HUMAN,tr|A0A804HJZ1|A0A804HJZ1_HUMAN,tr|C9JCA9|C9JCA9_HUMAN,tr|A0A804HIQ7|A0A804HIQ7_HUMAN,tr|A0A804HK30|A0A804HK30_HUMAN,tr|A0A804HKI2|A0A804HKI2_HUMAN,tr|A0A804HKR5|A0A804HKR5_HUMAN,tr|A0A804HKX0|A0A804HKX0_HUMAN,tr|A0A804HIG4|A0A804HIG4_HUMAN,tr|A0A804HK02|A0A804HK02_HUMAN" 22 2111.1375 0.6 55975 23796 4 2111.14272 528.7917 "Leucine-rich PPR motif-containing protein, mitochondrial OS=Homo sapiens OX=9606 GN=LRPPRC PE=1 SV=3" 6.42 3746 - 333952 - - - 2.4707 - 2.238 0.303 - 58.1 1 2 1 0.0052 20 0 0 0 3.33E+06 5.59E+06 - - - 2.1312 1 221125_WJC_METTL3_EV_vs_WT_F04.23807.23807.4 1.15E-11 23/108 K.NQLNPIGSLQELAIHHGWR[166.11].L "sp|O75569|PRKRA_HUMAN,tr|B4DJC7|B4DJC7_HUMAN,tr|A0A7I2V3J2|A0A7I2V3J2_HUMAN,tr|A0A7I2V2I8|A0A7I2V2I8_HUMAN,tr|A0A7I2V5H3|A0A7I2V5H3_HUMAN,tr|A0A7I2YQ87|A0A7I2YQ87_HUMAN" 6 2192.1478 1.51 55983 23807 4 2192.151515 549.0442 Interferon-inducible double-stranded RNA-dependent protein kinase activator A OS=Homo sapiens OX=9606 GN=PRKRA PE=1 SV=1 6.92 3747.4 - 632702 - - - 1.6769 - 3.836 0.645 - 534 1 2 0 0.0037 19 0 0 0 1.30E+07 8.60E+06 - - - 5.2939 1 221125_WJC_METTL3_EV_vs_WT_F04.23809.23809.3 3.11E-12 34/116 K.SPEEGAETPVYLALLPPDAEGPHGQFVSEK.R sp|P16152|CBR1_HUMAN 1 3163.535 1.65 55984 23809 3 3163.538699 1055.5189 Carbonyl reductase [NADPH] 1 OS=Homo sapiens OX=9606 GN=CBR1 PE=1 SV=3 4.14 3747.6 - 2.48E+06 - - - 1.1768 - 4.971 0.718 - 954.2 1 2 0 0.0037 30 0 0 0 3.73E+07 2.27E+07 - - - 10.2333 1 221125_WJC_METTL3_EV_vs_WT_F04.23810.23810.3 9.26E-10 22/64 K.HNIQFSSFDIFSDEEVR[166.11].Q sp|O76003|GLRX3_HUMAN 1 2078.9573 1.7 55985 23810 3 2078.95776 693.993 Glutaredoxin-3 OS=Homo sapiens OX=9606 GN=GLRX3 PE=1 SV=2 4.31 3747.8 - 1.54E+06 - - - 0.2193 - 3.942 0.635 - 768.3 1 2 0 0.0005 17 0 0 0 2.54E+07 1.49E+07 - - - 9.0848 1 221125_WJC_METTL3_EV_vs_WT_F04.23812.23812.3 6.69E-07 18/72 R.DSQLYAVDYETLTR[166.11]PFSGR[166.11].R "sp|P82930|RT34_HUMAN,tr|C9JJ19|C9JJ19_HUMAN" 2 2237.0868 1.04 55987 23812 3 2237.089576 746.7029 "28S ribosomal protein S34, mitochondrial OS=Homo sapiens OX=9606 GN=MRPS34 PE=1 SV=2" 4.56 3748 - 1.63E+06 - - - 1.2624 - 3.25 0.551 - 354.4 1 2 0 0.0028 19 0 0 0 2.57E+07 2.46E+07 - - - 7.578 0.9998 221125_WJC_METTL3_EV_vs_WT_F04.23813.23813.4 1.82E-06 18/162 R.TVSLGAGAK[136.11]DELHIVEAEAMNYEGSPIK[136.11].V "sp|P06748|NPM_HUMAN,tr|A0A7I2V4G8|A0A7I2V4G8_HUMAN,tr|A0A7I2YQC0|A0A7I2YQC0_HUMAN,tr|A0A7I2V433|A0A7I2V433_HUMAN,tr|A0A7I2V579|A0A7I2V579_HUMAN,tr|A0A7I2V2X9|A0A7I2V2X9_HUMAN,tr|A0A7I2V3G5|A0A7I2V3G5_HUMAN,tr|A0A7I2V5S2|A0A7I2V5S2_HUMAN,tr|A0A7I2V3U2|A0A7I2V3U2_HUMAN" 9 2944.4823 1.17 55988 23813 4 2944.485833 737.1278 Nucleophosmin OS=Homo sapiens OX=9606 GN=NPM1 PE=1 SV=2 4.57 3748.1 - 1.35E+06 - - - 1.2036 - 3.629 0.481 - 169 1 2 1 0.0035 28 0 0 0 6.75E+07 5.76E+07 - - - 3.8118 1 221125_WJC_METTL3_EV_vs_WT_F04.23820.23820.3 2.26E-08 21/64 K.HNIQFSSFDIFSDEEVR.Q sp|O76003|GLRX3_HUMAN 1 2068.949 1.7 55993 23820 3 2068.953167 690.657 Glutaredoxin-3 OS=Homo sapiens OX=9606 GN=GLRX3 PE=1 SV=2 4.31 3749 - 1.52E+06 - - - 1.9976 - 3.676 0.613 - 689.6 1 2 0 0.0041 17 0 0 0 2.54E+07 1.49E+07 - - - 8.662 1 221125_WJC_METTL3_EV_vs_WT_F04.23823.23823.3 2.13E-08 27/108 K.SGDAAIVDMVPGK[136.11]PMC[160.03]VESFSDYPPLGR[166.11].F "sp|P68104|EF1A1_HUMAN,sp|Q5VTE0|EF1A3_HUMAN,tr|A0A7I2V659|A0A7I2V659_HUMAN,tr|A0A087WVQ9|A0A087WVQ9_HUMAN" 4 3012.415 0.11 55996 23823 3 3012.422916 1005.1456 Elongation factor 1-alpha 1 OS=Homo sapiens OX=9606 GN=EEF1A1 PE=1 SV=1 4.23 3749.4 - 978044 - - - 2.6208 - 4.491 0.686 - 667.3 1 2 0 0.0079 28 0 0 0 6.28E+07 5.95E+08 - - - 9.6418 1 221125_WJC_METTL3_EV_vs_WT_F04.23830.23830.3 1.22E-13 30/116 K.SPEEGAETPVYLALLPPDAEGPHGQFVSEK[136.11].R sp|P16152|CBR1_HUMAN 1 3171.5492 1.63 56001 23830 3 3171.551733 1058.1903 Carbonyl reductase [NADPH] 1 OS=Homo sapiens OX=9606 GN=CBR1 PE=1 SV=3 4.14 3750.3 - 1.41E+06 - - - 0.8062 - 5.058 0.72 - 537.1 1 2 0 0.0026 30 0 0 0 3.69E+07 2.27E+07 - - - 10.2958 1 221125_WJC_METTL3_EV_vs_WT_F04.23831.23831.4 2.34E-07 21/102 K.NLVEQHIQDIVVHYTFNK[136.11].V "sp|P04843|RPN1_HUMAN,tr|B7Z4L4|B7Z4L4_HUMAN" 2 2204.147 1.4 56002 23831 4 2204.151006 552.044 Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit 1 OS=Homo sapiens OX=9606 GN=RPN1 PE=1 SV=1 5.99 3750.4 - 1.27E+06 - - - 1.8388 - 3.754 0.523 - 240.5 1 2 0 0.0041 18 0 0 0 1.84E+07 1.32E+07 - - - 4.2302 0.9986 221125_WJC_METTL3_EV_vs_WT_F04.23833.23833.4 0.0481 13/114 K.TLAYLLPAIVHINHQPYLER[166.11].G "sp|Q92841|DDX17_HUMAN,tr|A0A5H1ZRQ2|A0A5H1ZRQ2_HUMAN,tr|A0A1X7SBZ2|A0A1X7SBZ2_HUMAN" 3 2370.3088 1.06 56004 23833 4 2370.316262 593.5845 Probable ATP-dependent RNA helicase DDX17 OS=Homo sapiens OX=9606 GN=DDX17 PE=1 SV=2 6.61 3750.7 - 287977 - - - 3.1663 - 1.944 0.347 - 72 1 2 0 0.0075 20 0 0 0 6.42E+06 6.05E+06 - - - 2.4664 1 221125_WJC_METTL3_EV_vs_WT_F04.23834.23834.4 0.000834 18/162 K.SGDAAIVDMVPGK[136.11]PMC[160.03]VESFSDYPPLGR[166.11].F "sp|P68104|EF1A1_HUMAN,sp|Q5VTE0|EF1A3_HUMAN,tr|A0A7I2V659|A0A7I2V659_HUMAN,tr|A0A087WVQ9|A0A087WVQ9_HUMAN" 4 3012.415 0.26 56005 23834 4 3012.417 754.111 Elongation factor 1-alpha 1 OS=Homo sapiens OX=9606 GN=EEF1A1 PE=1 SV=1 4.23 3750.8 - 262165 - - - 0.6569 - 3.114 0.589 - 167.7 1 2 0 0.002 28 0 0 0 1.84E+07 7.12E+07 - - - 4.7048 0.9999 221125_WJC_METTL3_EV_vs_WT_F04.23835.23835.4 9.82E-07 21/114 K.TK[136.11]DLPVTEAVFSALVTGHAR[166.11].A "sp|P42704|LPPRC_HUMAN,tr|A0A804HI14|A0A804HI14_HUMAN,tr|A0A804HL40|A0A804HL40_HUMAN,tr|A0A804HKJ0|A0A804HKJ0_HUMAN,tr|A0A804HKR3|A0A804HKR3_HUMAN,tr|A0A0C4DG06|A0A0C4DG06_HUMAN,tr|A0A804HIN4|A0A804HIN4_HUMAN,tr|A0A804HLG8|A0A804HLG8_HUMAN,tr|A0A804HIV5|A0A804HIV5_HUMAN,tr|A0A804HHY9|A0A804HHY9_HUMAN,tr|A0A804HJH8|A0A804HJH8_HUMAN,tr|B8ZZ38|B8ZZ38_HUMAN,tr|A0A804HI40|A0A804HI40_HUMAN,tr|A0A804HJZ1|A0A804HJZ1_HUMAN,tr|C9JCA9|C9JCA9_HUMAN,tr|A0A804HIQ7|A0A804HIQ7_HUMAN,tr|A0A804HK30|A0A804HK30_HUMAN,tr|A0A804HKI2|A0A804HKI2_HUMAN,tr|A0A804HKR5|A0A804HKR5_HUMAN,tr|A0A804HKX0|A0A804HKX0_HUMAN,tr|A0A804HIG4|A0A804HIG4_HUMAN,tr|A0A804HK02|A0A804HK02_HUMAN" 22 2129.16 0.61 56006 23835 4 2129.162841 533.2973 "Leucine-rich PPR motif-containing protein, mitochondrial OS=Homo sapiens OX=9606 GN=LRPPRC PE=1 SV=3" 6.42 3750.9 - 244308 - - - 1.3465 - 2.856 0.512 - 248.6 1 2 1 0.0029 20 0 0 0 4.94E+06 8.07E+06 - - - 4.0325 1 221125_WJC_METTL3_EV_vs_WT_F04.23840.23840.3 5.24E-08 19/68 K.NLVEQHIQDIVVHYTFNK[136.11].V "sp|P04843|RPN1_HUMAN,tr|B7Z4L4|B7Z4L4_HUMAN" 2 2204.147 1.34 56009 23840 3 2204.14915 735.7229 Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit 1 OS=Homo sapiens OX=9606 GN=RPN1 PE=1 SV=1 5.99 3751.6 - 777210 - - - 0.9968 - 3.944 0.61 - 315.4 1 2 0 0.0022 18 0 0 0 1.30E+07 9.69E+06 - - - 8.7572 1 221125_WJC_METTL3_EV_vs_WT_F04.23841.23841.3 2.38E-09 22/68 K.NLVEQHIQDIVVHYTFNK.V "sp|P04843|RPN1_HUMAN,tr|B7Z4L4|B7Z4L4_HUMAN" 2 2196.1328 1.36 56010 23841 3 2196.14213 733.0515 Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit 1 OS=Homo sapiens OX=9606 GN=RPN1 PE=1 SV=1 5.99 3751.8 - 1.01E+06 - - - 4.2698 - 4.188 0.589 - 379.4 1 2 0 0.0094 18 0 0 0 1.32E+07 9.69E+06 - - - 8.6706 1 221125_WJC_METTL3_EV_vs_WT_F04.23842.23842.3 4.10E-06 18/56 R.LQAIEHELHELGLLK.D "sp|Q16769|QPCT_HUMAN,tr|B5MCZ9|B5MCZ9_HUMAN,tr|C9JS14|C9JS14_HUMAN" 3 1741.9727 1.52 56011 23842 3 1741.976501 581.6648 Glutaminyl-peptide cyclotransferase OS=Homo sapiens OX=9606 GN=QPCT PE=1 SV=1 5.33 3751.9 - 795904 - - - 2.1992 - 3.442 0.466 - 556 1 2 0 0.0038 15 0 0 0 1.79E+07 1.17E+07 - - - 6.9597 0.9999 221125_WJC_METTL3_EV_vs_WT_F04.23843.23843.4 0.000492 Nov-84 R.LQAIEHELHELGLLK.D "sp|Q16769|QPCT_HUMAN,tr|B5MCZ9|B5MCZ9_HUMAN,tr|C9JS14|C9JS14_HUMAN" 3 1741.9727 1.78 56012 23843 4 1741.975217 436.5004 Glutaminyl-peptide cyclotransferase OS=Homo sapiens OX=9606 GN=QPCT PE=1 SV=1 5.33 3752 - 614471 - - - 1.4621 - 2.596 0.406 - 116.5 1 2 0 0.0025 15 0 0 0 9.27E+06 5.20E+06 - - - 3.1005 0.9997 221125_WJC_METTL3_EV_vs_WT_F04.23846.23846.4 5.25E-06 18/114 K.TLAYLLPAIVHINHQPYLER.G "sp|Q92841|DDX17_HUMAN,tr|A0A5H1ZRQ2|A0A5H1ZRQ2_HUMAN,tr|A0A1X7SBZ2|A0A1X7SBZ2_HUMAN" 3 2360.3005 1.06 56015 23846 4 2360.312233 591.0824 Probable ATP-dependent RNA helicase DDX17 OS=Homo sapiens OX=9606 GN=DDX17 PE=1 SV=2 6.61 3752.4 - 468380 - - - 4.9765 - 2.986 0.556 - 176.7 1 2 0 0.0117 20 0 0 0 6.42E+06 6.05E+06 - - - 4.4279 0.9988 221125_WJC_METTL3_EV_vs_WT_F04.23848.23848.4 0.000672 Nov-84 R.LQAIEHELHELGLLK[136.11].D "sp|Q16769|QPCT_HUMAN,tr|B5MCZ9|B5MCZ9_HUMAN,tr|C9JS14|C9JS14_HUMAN" 3 1749.9869 1.78 56017 23848 4 1749.988348 438.504 Glutaminyl-peptide cyclotransferase OS=Homo sapiens OX=9606 GN=QPCT PE=1 SV=1 5.33 3752.6 - 428735 - - - 0.8446 - 2.168 0.283 - 105.9 1 2 0 0.0015 15 0 0 0 9.27E+06 5.20E+06 - - - 1.9657 1 221125_WJC_METTL3_EV_vs_WT_F04.23852.23852.4 6.30E-10 20/90 K.GLAPDLPEDLYHLIKK.A "sp|P62277|RS13_HUMAN,tr|J3KMX5|J3KMX5_HUMAN" 2 1821.0036 1.06 56020 23852 4 1821.006715 456.2582 40S ribosomal protein S13 OS=Homo sapiens OX=9606 GN=RPS13 PE=1 SV=2 5.38 3753.1 - 2.22E+06 - - - 1.6908 - 3.638 0.501 - 283.1 1 2 0 0.0031 16 0 0 0 4.08E+07 3.86E+07 - - - 4.0408 1 221125_WJC_METTL3_EV_vs_WT_F04.23855.23855.4 4.16E-08 24/156 K.YYAVNYPLRDGIDDESYEAIFKPVMSK.V sp|Q13547|HDAC1_HUMAN 1 3182.5271 1.36 56022 23855 4 3182.527608 796.639 Histone deacetylase 1 OS=Homo sapiens OX=9606 GN=HDAC1 PE=1 SV=1 4.44 3753.5 - 1.68E+06 - - - 0.1741 - 3.335 0.631 - 215.4 1 2 1 0.0006 27 0 0 0 1.79E+07 1.32E+07 - - - 5.0949 1 221125_WJC_METTL3_EV_vs_WT_F04.23856.23856.4 1.73E-09 29/234 R.GKPPPLLPSVLGPAGGDREALGLGPPAAQLTPPPAPVGLR.G "sp|Q8IY67|RAVR1_HUMAN,tr|E9PAU2|E9PAU2_HUMAN,tr|A0A087WZ13|A0A087WZ13_HUMAN" 3 3830.1571 1.32 56023 23856 4 3830.162957 958.5465 Ribonucleoprotein PTB-binding 1 OS=Homo sapiens OX=9606 GN=RAVER1 PE=1 SV=1 8.75 3753.6 - 1.40E+06 - - - 1.5386 - 3.628 0.643 - 195.3 1 2 1 0.0059 40 0 0 0 5.83E+07 4.43E+07 - - - 5.193 0.9999 221125_WJC_METTL3_EV_vs_WT_F04.23860.23860.3 0.000281 Nov-44 R.LFPPQWIC[160.03]C[160.03]DIR[166.11].Y sp|Q86U44|MTA70_HUMAN 1 1613.7722 0.001 56027 23860 3 1613.775046 538.9313 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 5.82 3754.1 - 379183 - - - 1.7574 - 1.814 0.506 - 176.7 1 2 0 0.0028 12 0 0 0 0.00E+00 1.48E+07 - - - 5.8313 0.9997 221125_WJC_METTL3_EV_vs_WT_F04.23863.23863.3 0.000263 Oct-56 R.DYLHLPPEIVPATLR.R "sp|P46783|RS10_HUMAN,tr|A0A2R8Y6L3|A0A2R8Y6L3_HUMAN,tr|F6U211|F6U211_HUMAN,tr|A0A1W2PQS6|A0A1W2PQS6_HUMAN,tr|A0A2R8YFH6|A0A2R8YFH6_HUMAN,tr|A0A2R8Y7H1|A0A2R8Y7H1_HUMAN,tr|S4R435|S4R435_HUMAN" 7 1732.9512 1.28 56030 23863 3 1732.95512 578.6577 40S ribosomal protein S10 OS=Homo sapiens OX=9606 GN=RPS10 PE=1 SV=1 5.32 3754.5 - 134068 - - - 2.2586 - 1.92 0.423 - 84.9 1 2 0 0.0039 15 0 0 0 3.49E+07 2.72E+07 - - - 4.9571 0.9988 221125_WJC_METTL3_EV_vs_WT_F04.23867.23867.3 0.00977 15/56 R.LQAIEHELHELGLLK[136.11].D "sp|Q16769|QPCT_HUMAN,tr|B5MCZ9|B5MCZ9_HUMAN,tr|C9JS14|C9JS14_HUMAN" 3 1749.9869 1.62 56033 23867 3 1750.988881 584.3362 Glutaminyl-peptide cyclotransferase OS=Homo sapiens OX=9606 GN=QPCT PE=1 SV=1 5.33 3755 - 765018 - - - 572.582 - 3.169 0.429 - 334.6 1 2 0 1.002 15 0 0 0 1.70E+07 1.05E+07 - - - 6.0551 1 221125_WJC_METTL3_EV_vs_WT_F04.23870.23870.3 2.92E-05 16/60 K.GLAPDLPEDLYHLIK[136.11]K[136.11].A "sp|P62277|RS13_HUMAN,tr|J3KMX5|J3KMX5_HUMAN" 2 1837.032 1.09 56035 23870 3 1837.034045 613.3513 40S ribosomal protein S13 OS=Homo sapiens OX=9606 GN=RPS13 PE=1 SV=2 5.38 3755.5 - 425160 - - - 1.0936 - 2.202 0.511 - 71.5 1 2 0 0.002 16 0 0 0 1.68E+07 1.54E+07 - - - 6.262 0.9999 221125_WJC_METTL3_EV_vs_WT_F04.23873.23873.4 8.97E-08 21/156 K.YYAVNYPLR[166.11]DGIDDESYEAIFK[136.11]PVMSK[136.11].V sp|Q13547|HDAC1_HUMAN 1 3208.5637 1.36 56037 23873 4 3208.569231 803.1482 Histone deacetylase 1 OS=Homo sapiens OX=9606 GN=HDAC1 PE=1 SV=1 4.44 3755.8 - 1.80E+06 - - - 1.7163 - 2.913 0.581 - 150.5 1 2 1 0.0055 27 0 0 0 1.79E+07 1.32E+07 - - - 4.616 0.9999 221125_WJC_METTL3_EV_vs_WT_F04.23874.23874.4 1.21E-06 33/234 R.GK[136.11]PPPLLPSVLGPAGGDR[166.11]EALGLGPPAAQLTPPPAPVGLR[166.11].G "sp|Q8IY67|RAVR1_HUMAN,tr|E9PAU2|E9PAU2_HUMAN,tr|A0A087WZ13|A0A087WZ13_HUMAN" 3 3858.1878 1.31 56038 23874 4 3858.19265 965.5542 Ribonucleoprotein PTB-binding 1 OS=Homo sapiens OX=9606 GN=RAVER1 PE=1 SV=1 8.75 3755.9 - 2.11E+06 - - - 1.256 - 3.706 0.581 - 250.2 1 2 1 0.0048 40 0 0 0 5.81E+07 4.43E+07 - - - 4.6598 0.9919 221125_WJC_METTL3_EV_vs_WT_F04.23876.23876.4 0.169 10/150 R.LVMGGPQQLYHLDAYIPLQINSHESK[136.11].A "sp|Q9NWS0|PIHD1_HUMAN,tr|M0QYA2|M0QYA2_HUMAN" 2 2958.5153 1.44 56040 23876 4 2958.518022 740.6361 PIH1 domain-containing protein 1 OS=Homo sapiens OX=9606 GN=PIH1D1 PE=1 SV=1 5.99 3756.2 - 669414 - - - 0.9153 - 2.229 0.203 - 47.1 1 2 0 0.0027 26 0 0 0 2.24E+08 1.55E+08 - - - 1.245 1 221125_WJC_METTL3_EV_vs_WT_F04.23881.23881.3 7.61E-06 16/60 K.K[136.11]VSQEILELLNTTTAK[136.11].E "sp|Q86U44|MTA70_HUMAN,tr|H0YFV6|H0YFV6_HUMAN" 2 1803.0324 0 56043 23881 3 1803.032126 602.0181 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 6.14 3756.7 - 6.53E+06 - - - -0.1686 - 3.659 0.667 - 528.8 1 2 0 -0.0003 16 0 0 0 6.56E+05 1.46E+08 - - - 9.3047 1 221125_WJC_METTL3_EV_vs_WT_F04.23884.23884.3 2.90E-11 23/108 K.SGDAAIVDMVPGKPMC[160.03]VESFSDYPPLGR.F "sp|P68104|EF1A1_HUMAN,sp|Q5VTE0|EF1A3_HUMAN,tr|A0A7I2V659|A0A7I2V659_HUMAN,tr|A0A087WVQ9|A0A087WVQ9_HUMAN" 4 2994.3926 0.11 56046 23884 3 2994.383713 999.1381 Elongation factor 1-alpha 1 OS=Homo sapiens OX=9606 GN=EEF1A1 PE=1 SV=1 4.23 3757 - 1.90E+06 - - - -2.9515 - 4.09 0.696 - 491.8 1 2 0 -0.0088 28 0 0 0 6.28E+07 5.93E+08 - - - 9.5378 0.9999 221125_WJC_METTL3_EV_vs_WT_F04.23887.23887.4 5.52E-12 25/150 K.SGFEPASLKEEVGEEAIVELVENGKK.V "sp|P35579|MYH9_HUMAN,tr|Q5BKV1|Q5BKV1_HUMAN,tr|B1AH99|B1AH99_HUMAN" 3 2787.4178 1.12 56049 23887 4 2787.425195 697.8617 Myosin-9 OS=Homo sapiens OX=9606 GN=MYH9 PE=1 SV=4 4.36 3757.4 - 848722 - - - 2.6455 - 4.151 0.595 - 346.4 1 2 1 0.0074 26 0 0 0 1.29E+08 1.16E+08 - - - 4.8518 1 221125_WJC_METTL3_EV_vs_WT_F04.23890.23890.3 1.98E-17 23/140 K.GIQNIDPESDPYVTPGSVLGGTATSPIVDTDHQLLR.D "sp|Q9UPQ9|TNR6B_HUMAN,tr|H0Y720|H0Y720_HUMAN" 2 3761.8748 5.66 56052 23890 3 3761.884204 1254.9655 Trinucleotide repeat-containing gene 6B protein OS=Homo sapiens OX=9606 GN=TNRC6B PE=1 SV=4 4.03 3757.8 - 492805 - - - 2.4961 - 4.373 0.718 - 365.3 1 2 0 0.0094 36 0 0 0 6.86E+06 1.21E+06 - - - 9.9369 1 221125_WJC_METTL3_EV_vs_WT_F04.23891.23891.3 3.94E-11 19/100 K.ENYLTAGLTVGQVRPLVPLQPVTQNR.A sp|Q99959|PKP2_HUMAN 1 2862.5716 2.65 56053 23891 3 2862.574317 955.1978 Plakophilin-2 OS=Homo sapiens OX=9606 GN=PKP2 PE=1 SV=2 8.85 3758 - 316324 - - - 0.9575 - 3.38 0.733 - 311.2 1 2 0 0.0027 26 0 0 0 8.89E+06 3.35E+06 - - - 9.5134 0.9998 221125_WJC_METTL3_EV_vs_WT_F04.23895.23895.4 8.00E-06 16/150 K.SGFEPASLK[136.11]EEVGEEAIVELVENGK[136.11]K[136.11].V "sp|P35579|MYH9_HUMAN,tr|Q5BKV1|Q5BKV1_HUMAN,tr|B1AH99|B1AH99_HUMAN" 3 2811.4604 1.12 56055 23895 4 2811.464837 703.8724 Myosin-9 OS=Homo sapiens OX=9606 GN=MYH9 PE=1 SV=4 4.36 3758.4 - 3.31E+06 - - - 1.5707 - 2.925 0.484 - 114.5 1 2 1 0.0044 26 0 0 0 1.29E+08 1.16E+08 - - - 3.7761 0.9999 221125_WJC_METTL3_EV_vs_WT_F04.23897.23897.4 0.000328 18/150 R.LVMGGPQQLYHLDAYIPLQINSHESK.A "sp|Q9NWS0|PIHD1_HUMAN,tr|M0QYA2|M0QYA2_HUMAN" 2 2950.5011 1.44 56057 23897 4 2950.507072 738.6326 PIH1 domain-containing protein 1 OS=Homo sapiens OX=9606 GN=PIH1D1 PE=1 SV=1 5.99 3758.6 - 2.94E+06 - - - 2.0193 - 2.733 0.442 - 124.3 1 2 0 0.006 26 0 0 0 2.23E+08 1.55E+08 - - - 3.3887 0.9999 221125_WJC_METTL3_EV_vs_WT_F04.23899.23899.4 1.39E-08 21/144 R.IASLPVEVQEVSLLDKITDKESGER.L "sp|Q96P16|RPR1A_HUMAN,tr|A0A0C4DGQ6|A0A0C4DGQ6_HUMAN,tr|K7EP82|K7EP82_HUMAN" 3 2754.4651 2.14 56059 23899 4 2754.470756 689.6236 Regulation of nuclear pre-mRNA domain-containing protein 1A OS=Homo sapiens OX=9606 GN=RPRD1A PE=1 SV=1 4.36 3758.8 - 1.26E+06 - - - 2.0516 - 4.458 0.612 - 288.8 1 2 2 0.0057 25 0 0 0 8.87E+06 4.14E+06 - - - 5.0268 1 221125_WJC_METTL3_EV_vs_WT_F04.23902.23902.3 1.13E-08 15/84 K.NNFSDTGNFGFGIQEHIDLGIK[136.11].Y "sp|P62913|RL11_HUMAN,tr|Q5VVC8|Q5VVC8_HUMAN" 2 2430.1695 9.97 56062 23902 3 2430.176427 811.0638 60S ribosomal protein L11 OS=Homo sapiens OX=9606 GN=RPL11 PE=1 SV=2 4.54 3759.2 - 699955 - - - 2.8344 - 2.941 0.604 - 187.3 1 2 0 0.0069 22 0 0 0 7.02E+07 7.05E+06 - - - 7.8296 0.9999 221125_WJC_METTL3_EV_vs_WT_F04.23904.23904.3 0.000128 Dec-76 K.DTQDIVHDLESPGIDPSIIK.Q "sp|Q9UPN3|MACF1_HUMAN,tr|A0A804HL78|A0A804HL78_HUMAN,tr|H3BQK9|H3BQK9_HUMAN,tr|A0A7P0MQR8|A0A7P0MQR8_HUMAN,tr|H0Y390|H0Y390_HUMAN,tr|H3BPE1|H3BPE1_HUMAN,tr|A0A590UJG2|A0A590UJG2_HUMAN" 7 2191.1008 11.86 56064 23904 3 2191.104448 731.3742 "Microtubule-actin cross-linking factor 1, isoforms 1\2\3\5 OS=Homo sapiens OX=9606 GN=MACF1 PE=1 SV=4" 4.03 3759.5 - 596991 - - - 1.6453 - 2.615 0.419 - 90.3 1 2 0 0.0036 20 0 0 0 5.17E+06 4.35E+05 - - - 5.5425 1 221125_WJC_METTL3_EV_vs_WT_F04.23905.23905.4 7.77E-06 27/126 K.TSQLLETLNQLSTHTHVVDITR.T "sp|Q14203|DCTN1_HUMAN,tr|A0A804CDA6|A0A804CDA6_HUMAN,tr|E7EX90|E7EX90_HUMAN,tr|A0A7P0Z4C3|A0A7P0Z4C3_HUMAN,tr|E7EWF7|E7EWF7_HUMAN" 5 2505.3187 1.98 56065 23905 4 2505.324686 627.337 Dynactin subunit 1 OS=Homo sapiens OX=9606 GN=DCTN1 PE=1 SV=3 5.92 3759.6 - 534638 - - - 2.3829 - 4.935 0.584 - 937.7 1 2 0 0.006 22 0 0 0 6.57E+06 3.32E+06 - - - 4.8298 0.9993 221125_WJC_METTL3_EV_vs_WT_F04.23909.23909.4 0.000147 15/96 R.DAWGRLPVDLAEELGHR.D "sp|P42771|CDN2A_HUMAN,tr|K7ENC6|K7ENC6_HUMAN,tr|J3QRG6|J3QRG6_HUMAN,tr|K7ES20|K7ES20_HUMAN" 4 1932.9806 3.57 56069 23909 4 1932.981756 484.2524 Cyclin-dependent kinase inhibitor 2A OS=Homo sapiens OX=9606 GN=CDKN2A PE=1 SV=2 4.75 3760.1 - 238770 - - - 0.5934 - 2.507 0.385 - 132 1 2 1 0.0011 17 0 0 0 3.17E+06 8.87E+05 - - - 2.8958 1 221125_WJC_METTL3_EV_vs_WT_F04.23914.23914.3 1.49E-08 19/104 K.NFQNIFPPSATLHLSNIPPSVSEEDLK[136.11].V "sp|P26599|PTBP1_HUMAN,tr|A0A0U1RRM4|A0A0U1RRM4_HUMAN,tr|A6NLN1|A6NLN1_HUMAN,tr|A0A0D9SF20|A0A0D9SF20_HUMAN,tr|A0A7I2V621|A0A7I2V621_HUMAN" 5 3001.5277 0.86 56072 23914 3 3001.526699 1001.5165 Polypyrimidine tract-binding protein 1 OS=Homo sapiens OX=9606 GN=PTBP1 PE=1 SV=1 4.65 3760.7 - 5.29E+06 - - - -0.3175 - 3.406 0.521 - 174.4 1 2 0 -0.001 27 0 0 0 1.68E+08 1.96E+08 - - - 7.1679 1 221125_WJC_METTL3_EV_vs_WT_F04.23918.23918.3 3.14E-08 26/100 K.SGFEPASLKEEVGEEAIVELVENGKK.V "sp|P35579|MYH9_HUMAN,tr|Q5BKV1|Q5BKV1_HUMAN,tr|B1AH99|B1AH99_HUMAN" 3 2787.4178 2.66 56076 23918 3 2787.425467 930.1466 Myosin-9 OS=Homo sapiens OX=9606 GN=MYH9 PE=1 SV=4 4.36 3761.1 - 1.62E+06 - - - 2.743 - 4.779 0.673 - 603.3 1 2 1 0.0076 26 0 0 0 2.65E+07 9.98E+06 - - - 9.6399 0.9997 221125_WJC_METTL3_EV_vs_WT_F04.23920.23920.3 1.09E-05 18/64 R.DAWGRLPVDLAEELGHR.D "sp|P42771|CDN2A_HUMAN,tr|K7ENC6|K7ENC6_HUMAN,tr|J3QRG6|J3QRG6_HUMAN,tr|K7ES20|K7ES20_HUMAN" 4 1932.9806 7.69 56078 23920 3 1932.981452 645.3341 Cyclin-dependent kinase inhibitor 2A OS=Homo sapiens OX=9606 GN=CDKN2A PE=1 SV=2 4.75 3761.4 - 850768 - - - 0.4361 - 2.492 0.419 - 271.2 1 2 1 0.0008 17 0 0 0 1.50E+07 1.96E+06 - - - 5.5179 0.8041 221125_WJC_METTL3_EV_vs_WT_F04.23926.23926.4 0.143 10/120 R.AEEEDEKGTAGGLLSSLEGLK[136.11].M "sp|Q8NFM4|ADCY4_HUMAN,tr|H0YJ57|H0YJ57_HUMAN" 2 2140.0627 - 56082 23926 4 2140.048897 536.0229 Adenylate cyclase type 4 OS=Homo sapiens OX=9606 GN=ADCY4 PE=1 SV=1 4.14 3762.1 - 1.22E+06 - - - -6.4377 - 1.632 0.281 - 27.9 1 2 1 -0.0138 21 0 0 0 - - - - - 1.83 0.9618 221125_WJC_METTL3_EV_vs_WT_F04.23927.23927.2 0.000925 14-Aug K.DIGFIK[136.11]LD.- "sp|P62273|RS29_HUMAN,tr|A0A087WTT6|A0A087WTT6_HUMAN" 2 927.5157 1.1 56083 23927 2 927.514767 464.7651 40S ribosomal protein S29 OS=Homo sapiens OX=9606 GN=RPS29 PE=1 SV=2 4.54 3762.2 - 885961 - - - -0.9887 - 1.399 0.194 - 113.8 1 2 1 -0.0009 8 0 0 0 2.02E+07 1.84E+07 - - - 1.4862 0.99 221125_WJC_METTL3_EV_vs_WT_F04.23929.23929.3 0.25 Aug-60 R.HDYWLLAGIINHGYAR.W "sp|Q14839|CHD4_HUMAN,tr|A0A2R8Y4X2|A0A2R8Y4X2_HUMAN,tr|A0A2U3TZM0|A0A2U3TZM0_HUMAN,tr|A0A2R8YD40|A0A2R8YD40_HUMAN,tr|A0A2R8Y5J0|A0A2R8Y5J0_HUMAN,tr|A0A2R8Y425|A0A2R8Y425_HUMAN,tr|A0A2R8YFK9|A0A2R8YFK9_HUMAN,tr|A0A0C4DGG9|A0A0C4DGG9_HUMAN,tr|A0A2R8YFD8|A0A2R8YFD8_HUMAN,tr|A0A2R8YDW2|A0A2R8YDW2_HUMAN,tr|A0A2R8Y7I0|A0A2R8Y7I0_HUMAN,tr|F5GWX5|F5GWX5_HUMAN,tr|A0A2R8Y7M9|A0A2R8Y7M9_HUMAN,tr|A0A2R8Y521|A0A2R8Y521_HUMAN,tr|A0A2R8YDJ9|A0A2R8YDJ9_HUMAN,tr|A0A2R8Y212|A0A2R8Y212_HUMAN" 16 1897.9588 43.1 56085 23929 3 1897.955489 633.6602 Chromodomain-helicase-DNA-binding protein 4 OS=Homo sapiens OX=9606 GN=CHD4 PE=1 SV=2 6.92 3762.5 - 571149 - - - -1.7187 - 1.655 0.199 - 41.9 1 2 0 -0.0033 16 0 0 0 1.49E+07 3.46E+05 - - - 2.0504 0.9999 221125_WJC_METTL3_EV_vs_WT_F04.23932.23932.2 8.55E-07 22-Sep R.LFPPQWIC[160.03]C[160.03]DIR[166.11].Y sp|Q86U44|MTA70_HUMAN 1 1613.7722 0 56086 23932 2 1613.772524 807.8934 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 5.82 3762.9 - 2.18E+06 - - - 0.1946 - 1.992 0.525 - 230.1 1 2 0 0.0003 12 0 0 0 2.96E+05 7.42E+07 - - - 4.7318 1 221125_WJC_METTL3_EV_vs_WT_F04.23933.23933.3 4.18E-12 24/92 R.EGPIDLGAC[160.03]NQDDWISAVRPVIEK.R "sp|Q9Y5K5|UCHL5_HUMAN,tr|H0Y4E0|H0Y4E0_HUMAN,tr|Q5LJA9|Q5LJA9_HUMAN,tr|H0Y6Y4|H0Y6Y4_HUMAN,tr|Q5LJB0|Q5LJB0_HUMAN,tr|Q5LJA5|Q5LJA5_HUMAN" 6 2681.3119 3.17 56087 23933 3 2681.310834 894.7779 Ubiquitin carboxyl-terminal hydrolase isozyme L5 OS=Homo sapiens OX=9606 GN=UCHL5 PE=1 SV=3 4.11 3763 - 3.06E+06 - - - -0.4035 - 4.17 0.706 - 578.8 1 2 0 -0.0011 24 0 0 0 1.59E+08 5.02E+07 - - - 9.7274 0.9999 221125_WJC_METTL3_EV_vs_WT_F04.23935.23935.4 2.13E-06 25/144 K.ISVIVETVYTHVLHPYPTQITQSEK[136.11].Q sp|P04843|RPN1_HUMAN 1 2889.5368 1.17 56089 23935 4 2889.525084 723.3915 Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit 1 OS=Homo sapiens OX=9606 GN=RPN1 PE=1 SV=1 6 3763.1 - 2.70E+06 - - - -4.0408 - 4.667 0.546 - 359.3 1 2 0 -0.0117 25 0 0 0 8.00E+07 6.84E+07 - - - 4.4652 1 221125_WJC_METTL3_EV_vs_WT_F04.23938.23938.4 9.95E-09 22/180 R.APHLVGPHLGLETGNGGGVINLNAFDPTLPK.T "sp|Q6P2I3|FAH2B_HUMAN,sp|Q96GK7|FAH2A_HUMAN,tr|C9J5B6|C9J5B6_HUMAN,tr|C9JGM0|C9JGM0_HUMAN" 4 3104.6407 1.36 56092 23938 4 3104.638141 777.1675 Fumarylacetoacetate hydrolase domain-containing protein 2B OS=Homo sapiens OX=9606 GN=FAHD2B PE=1 SV=1 6 3763.5 - 1.07E+06 - - - -0.8304 - 3.324 0.54 - 254.9 1 2 0 -0.0026 31 0 0 0 1.88E+07 1.38E+07 - - - 4.2905 1 221125_WJC_METTL3_EV_vs_WT_F04.23940.23940.4 1.00E-11 21/114 R.DGVSEGQFQQVLHHELLAIR.E sp|Q9UKV8|AGO2_HUMAN 1 2275.1709 1.2 56094 23940 4 2275.176796 569.8 Protein argonaute-2 OS=Homo sapiens OX=9606 GN=AGO2 PE=1 SV=3 5.27 3763.8 - 771052 - - - 2.5787 - 4.191 0.679 - 474.5 1 2 0 0.0059 20 0 0 0 6.12E+06 5.10E+06 - - - 5.6135 0.9999 221125_WJC_METTL3_EV_vs_WT_F04.23943.23943.3 1.75E-09 20/104 K.NFQNIFPPSATLHLSNIPPSVSEEDLK.V "sp|P26599|PTBP1_HUMAN,tr|A0A0U1RRM4|A0A0U1RRM4_HUMAN,tr|A6NLN1|A6NLN1_HUMAN,tr|A0A0D9SF20|A0A0D9SF20_HUMAN,tr|A0A7I2V621|A0A7I2V621_HUMAN" 5 2993.5135 0.86 56095 23943 3 2993.525571 998.8451 Polypyrimidine tract-binding protein 1 OS=Homo sapiens OX=9606 GN=PTBP1 PE=1 SV=1 4.65 3764.1 - 9.77E+06 - - - 4.0484 - 3.059 0.58 - 235.6 1 2 0 0.0121 27 0 0 0 1.68E+08 1.96E+08 - - - 7.5754 1 221125_WJC_METTL3_EV_vs_WT_F04.23944.23944.4 3.41E-08 22/144 K.ISVIVETVYTHVLHPYPTQITQSEK.Q sp|P04843|RPN1_HUMAN 1 2881.5226 1.1 56096 23944 4 2881.515882 721.3879 Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit 1 OS=Homo sapiens OX=9606 GN=RPN1 PE=1 SV=1 6 3764.2 - 4.80E+06 - - - -2.3175 - 3.593 0.518 - 232.2 1 2 0 -0.0067 25 0 0 0 8.27E+07 7.48E+07 - - - 4.1397 1 221125_WJC_METTL3_EV_vs_WT_F04.23948.23948.3 3.93E-08 19/56 R.QGDTGDWIGTFLGHK.G sp|Q9Y3F4|STRAP_HUMAN 1 1630.774 0.67 56098 23948 3 1630.773466 544.5986 Serine-threonine kinase receptor-associated protein OS=Homo sapiens OX=9606 GN=STRAP PE=1 SV=1 5.21 3764.7 - 3.47E+06 - - - -0.3091 - 2.131 0.575 - 415.5 1 2 0 -0.0005 15 0 0 0 7.97E+07 1.19E+08 - - - 6.9248 0.8619 221125_WJC_METTL3_EV_vs_WT_F04.23951.23951.2 0.122 14-Jul K.DIGFIKLD.- "sp|P62273|RS29_HUMAN,tr|A0A087WTT6|A0A087WTT6_HUMAN" 2 919.5015 1.1 56101 23951 2 919.499987 460.758 40S ribosomal protein S29 OS=Homo sapiens OX=9606 GN=RPS29 PE=1 SV=2 4.54 3764.9 - 1.12E+06 - - - -1.6281 - 1.143 0.175 - 89 1 2 1 -0.0015 8 0 0 0 2.02E+07 1.84E+07 - - - 0.7362 0.9999 221125_WJC_METTL3_EV_vs_WT_F04.23954.23954.3 6.25E-06 Nov-56 R.QGDTGDWIGTFLGHK[136.11].G sp|Q9Y3F4|STRAP_HUMAN 1 1638.7882 0.67 56102 23954 3 1638.787173 547.27 Serine-threonine kinase receptor-associated protein OS=Homo sapiens OX=9606 GN=STRAP PE=1 SV=1 5.21 3765.3 - 7.69E+06 - - - -0.6084 - 1.572 0.513 - 129.3 1 2 0 -0.001 15 0 0 0 7.97E+07 1.19E+08 - - - 5.4395 1 221125_WJC_METTL3_EV_vs_WT_F04.23955.23955.3 1.52E-10 29/92 R.EGPIDLGAC[160.03]NQDDWISAVR[166.11]PVIEK[136.11].R "sp|Q9Y5K5|UCHL5_HUMAN,tr|H0Y4E0|H0Y4E0_HUMAN,tr|Q5LJA9|Q5LJA9_HUMAN,tr|H0Y6Y4|H0Y6Y4_HUMAN,tr|Q5LJB0|Q5LJB0_HUMAN,tr|Q5LJA5|Q5LJA5_HUMAN" 6 2699.3344 3.17 56103 23955 3 2699.333082 900.7854 Ubiquitin carboxyl-terminal hydrolase isozyme L5 OS=Homo sapiens OX=9606 GN=UCHL5 PE=1 SV=3 4.11 3765.4 - 4.37E+06 - - - -0.4831 - 4.301 0.72 - 926.2 1 2 0 -0.0013 24 0 0 0 1.59E+08 5.02E+07 - - - 9.9552 0.9999 221125_WJC_METTL3_EV_vs_WT_F04.23960.23960.3 9.20E-05 19/144 K.LYQSAGGMPGGMPGGFPGGGAPPSGGASSGPTIEEVD.- "sp|P11142|HSP7C_HUMAN,tr|E9PNE6|E9PNE6_HUMAN,tr|A8K7Q2|A8K7Q2_HUMAN,tr|E9PKE3|E9PKE3_HUMAN" 4 3345.4918 - 56105 23960 3 3345.488596 1116.1712 Heat shock cognate 71 kDa protein OS=Homo sapiens OX=9606 GN=HSPA8 PE=1 SV=1 3.88 3766.1 - 2.05E+06 - - - -0.9598 - 2.917 0.422 - 138.7 1 2 0 -0.0032 37 0 0 0 - - - - - 5.707 1 221125_WJC_METTL3_EV_vs_WT_F04.23961.23961.3 4.14E-13 30/104 F.QSTLVIAEHANDSLAPITLNTITAATR.L "sp|P13804|ETFA_HUMAN,tr|J3KN60|J3KN60_HUMAN,tr|H0YKF0|H0YKF0_HUMAN,tr|H0YLU7|H0YLU7_HUMAN" 4 2820.4981 1.72 56106 23961 3 2820.49872 941.1733 "Electron transfer flavoprotein subunit alpha, mitochondrial OS=Homo sapiens OX=9606 GN=ETFA PE=1 SV=1" 5.32 3766.2 - 3.25E+06 - - - 0.2067 - 4.391 0.678 - 643.1 1 1 0 0.0006 27 0 0 0 3.52E+07 2.05E+07 - - - 9.5028 1 221125_WJC_METTL3_EV_vs_WT_F04.23967.23967.3 2.96E-12 24/92 R.SHELDIDENPASDFDDSGSLLGFK.Y sp|Q96RS0|TGS1_HUMAN 1 2607.1613 1.59 56110 23967 3 2607.154892 870.061 Trimethylguanosine synthase OS=Homo sapiens OX=9606 GN=TGS1 PE=1 SV=3 3.85 3767 - 1.38E+06 - - - -2.4471 - 4.712 0.764 - 630.3 1 2 0 -0.0064 24 0 0 0 2.04E+07 1.29E+07 - - - 10.6564 1 221125_WJC_METTL3_EV_vs_WT_F04.23969.23969.3 4.68E-11 23/120 R.GGSPYNQFDIIPGDTLGGHTGPAGDSWLPAK.S "sp|Q9UPQ9|TNR6B_HUMAN,tr|H0Y720|H0Y720_HUMAN" 2 3124.489 12.71 56112 23969 3 3124.482728 1042.5036 Trinucleotide repeat-containing gene 6B protein OS=Homo sapiens OX=9606 GN=TNRC6B PE=1 SV=4 4.41 3767.2 - 1.16E+06 - - - -2.0166 - 3.883 0.703 - 257.1 1 2 0 -0.0063 31 0 0 0 1.64E+07 1.29E+06 - - - 9.4971 0.9515 221125_WJC_METTL3_EV_vs_WT_F04.23977.23977.3 2.96E-10 17/104 F.QSTLVIAEHANDSLAPITLNTITAATR[166.11].L "sp|P13804|ETFA_HUMAN,tr|J3KN60|J3KN60_HUMAN,tr|H0YKF0|H0YKF0_HUMAN,tr|H0YLU7|H0YLU7_HUMAN" 4 2830.5064 1.72 56118 23977 3 2831.513034 944.5094 "Electron transfer flavoprotein subunit alpha, mitochondrial OS=Homo sapiens OX=9606 GN=ETFA PE=1 SV=1" 5.32 3768.1 - 1.13E+06 - - - 355.6349 - 3.202 0.6 - 217.6 1 1 0 1.0066 27 0 0 0 3.52E+07 2.05E+07 - - - 7.628 1 221125_WJC_METTL3_EV_vs_WT_F04.23984.23984.4 2.49E-16 28/174 K.MMVDKDGDVTVTNDGATILSMMDVDHQIAK.L "sp|P48643|TCPE_HUMAN,tr|E9PCA1|E9PCA1_HUMAN,tr|B7ZAR1|B7ZAR1_HUMAN" 3 3249.5026 0.38 56122 23984 4 3249.501875 813.3829 T-complex protein 1 subunit epsilon OS=Homo sapiens OX=9606 GN=CCT5 PE=1 SV=1 4.11 3768.9 - 3.71E+06 - - - -0.2145 - 5.809 0.711 - 517.7 1 2 1 -0.0007 30 0 0 0 3.04E+07 7.93E+07 - - - 5.9527 0.9976 221125_WJC_METTL3_EV_vs_WT_F04.23985.23985.4 0.00298 9/126 K.EVIELPVK[136.11]HPELFEALGIAQPK[136.11].G "sp|P62195|PRS8_HUMAN,tr|J3QQM1|J3QQM1_HUMAN,tr|J3KRP2|J3KRP2_HUMAN,tr|J3QRR3|J3QRR3_HUMAN,tr|J3QSA9|J3QSA9_HUMAN,tr|J3QLH6|J3QLH6_HUMAN,tr|J3QSE0|J3QSE0_HUMAN,tr|J3QRW1|J3QRW1_HUMAN" 8 2472.3963 1.08 56123 23985 4 2472.396946 619.1064 26S proteasome regulatory subunit 8 OS=Homo sapiens OX=9606 GN=PSMC5 PE=1 SV=1 4.91 3769 - 2.26E+06 - - - 0.2621 - 1.955 0.324 - 48.5 1 2 1 0.0006 22 0 0 0 2.05E+07 1.90E+07 - - - 2.2653 1 221125_WJC_METTL3_EV_vs_WT_F04.23986.23986.3 4.15E-06 17/68 R.QELEIVIGDEHISFTTSK.L "sp|Q96A72|MGN2_HUMAN,sp|P61326|MGN_HUMAN,tr|F5H6P7|F5H6P7_HUMAN" 3 2045.0317 5.89 56124 23986 3 2045.033566 682.6845 Protein mago nashi homolog 2 OS=Homo sapiens OX=9606 GN=MAGOHB PE=1 SV=1 4.4 3769.1 - 1.34E+06 - - - 0.912 - 3.235 0.51 - 347.1 1 2 0 0.0019 18 0 0 0 1.39E+07 2.36E+06 - - - 7.1489 1 221125_WJC_METTL3_EV_vs_WT_F04.23987.23987.3 6.73E-11 19/80 K.R[166.11]IDTPSLEEPSDLEELEQFAK[136.11].T "sp|P14859|PO2F1_HUMAN,tr|A0A0C4DG88|A0A0C4DG88_HUMAN" 2 2463.2136 2.06 56125 23987 3 2463.218021 822.0785 "POU domain, class 2, transcription factor 1 OS=Homo sapiens OX=9606 GN=POU2F1 PE=1 SV=2" 4 3769.2 - 1.22E+06 - - - 1.8009 - 4.123 0.618 - 426 1 2 0 0.0044 21 0 0 0 2.94E+08 1.42E+08 - - - 8.825 1 221125_WJC_METTL3_EV_vs_WT_F04.23991.23991.3 4.17E-11 18/84 K.EVIELPVK[136.11]HPELFEALGIAQPK[136.11].G "sp|P62195|PRS8_HUMAN,tr|J3QQM1|J3QQM1_HUMAN,tr|J3KRP2|J3KRP2_HUMAN,tr|J3QRR3|J3QRR3_HUMAN,tr|J3QSA9|J3QSA9_HUMAN,tr|J3QLH6|J3QLH6_HUMAN,tr|J3QSE0|J3QSE0_HUMAN,tr|J3QRW1|J3QRW1_HUMAN" 8 2472.3963 0.72 56129 23991 3 2472.396462 825.1394 26S proteasome regulatory subunit 8 OS=Homo sapiens OX=9606 GN=PSMC5 PE=1 SV=1 4.91 3769.7 - 674069 - - - 0.0663 - 4.026 0.651 - 302.7 1 2 1 0.0002 22 0 0 0 5.19E+06 7.17E+06 - - - 9.1 0.9999 221125_WJC_METTL3_EV_vs_WT_F04.23992.23992.3 0.000439 14/68 R.IGPYQPNVPVGIDYVIPK.T "sp|P43243|MATR3_HUMAN,tr|B3KM87|B3KM87_HUMAN,tr|A8MXP9|A8MXP9_HUMAN,tr|A0A0R4J2E8|A0A0R4J2E8_HUMAN" 4 1968.072 1.34 56130 23992 3 1968.075537 657.0313 Matrin-3 OS=Homo sapiens OX=9606 GN=MATR3 PE=1 SV=2 5.83 3769.8 - 666550 - - - 1.7718 - 2.855 0.473 - 211.5 1 2 0 0.0035 18 0 0 0 1.21E+07 9.01E+06 - - - 6.4248 0.9951 221125_WJC_METTL3_EV_vs_WT_F04.23996.23996.4 0.0418 14/138 K.HISQISVAEDDDESLLGHLMIVGK[136.11].K sp|P49773|HINT1_HUMAN 1 2613.32 1 56134 23996 4 2613.320398 654.3373 Adenosine 5'-monophosphoramidase HINT1 OS=Homo sapiens OX=9606 GN=HINT1 PE=1 SV=2 4.42 3770.4 - 502378 - - - 0.1645 - 1.764 0.232 - 33.6 1 2 0 0.0004 24 0 0 0 3.06E+06 3.05E+06 - - - 1.4274 1 221125_WJC_METTL3_EV_vs_WT_F04.24002.24002.3 1.22E-10 24/80 K.RIDTPSLEEPSDLEELEQFAK.T "sp|P14859|PO2F1_HUMAN,tr|A0A0C4DG88|A0A0C4DG88_HUMAN" 2 2445.1911 2.06 56138 24002 3 2445.195208 816.071 "POU domain, class 2, transcription factor 1 OS=Homo sapiens OX=9606 GN=POU2F1 PE=1 SV=2" 4 3771 - 1.23E+07 - - - 1.6739 - 4.498 0.709 - 606.7 1 2 0 0.0041 21 0 0 0 2.94E+08 1.42E+08 - - - 10.0484 1 221125_WJC_METTL3_EV_vs_WT_F04.24005.24005.3 1.56E-10 21/92 R.QNIVLPSDEKGELDLSLENLDLSK.D sp|Q01804|OTUD4_HUMAN 1 2668.3807 3.77 56141 24005 3 2668.381453 890.4675 OTU domain-containing protein 4 OS=Homo sapiens OX=9606 GN=OTUD4 PE=1 SV=4 4.02 3771.3 - 1.52E+06 - - - 0.2796 - 3.873 0.623 - 545.4 1 2 1 0.0007 24 0 0 0 9.65E+06 2.56E+06 - - - 8.6305 0.9985 221125_WJC_METTL3_EV_vs_WT_F04.24009.24009.3 0.0161 Nov-76 K.QKDFLDGVYAFEYYPSTPGR.Y "sp|O75369|FLNB_HUMAN,tr|E7EN95|E7EN95_HUMAN,tr|A0A804HK76|A0A804HK76_HUMAN,tr|A0A804HL72|A0A804HL72_HUMAN" 4 2352.1063 0.81 56145 24009 3 2352.108723 785.0427 Filamin-B OS=Homo sapiens OX=9606 GN=FLNB PE=1 SV=2 4.56 3771.8 - 779355 - - - 1.0459 - 2.202 0.339 - 78.6 1 2 1 0.0025 20 0 0 0 4.58E+06 5.64E+06 - - - 4.2339 0.9996 221125_WJC_METTL3_EV_vs_WT_F04.24010.24010.3 0.0236 Oct-76 R.K[136.11]PGADLSDYFNYGFNEDTWK[136.11].A "sp|Q6UN15|FIP1_HUMAN,tr|A0A0B4J203|A0A0B4J203_HUMAN" 2 2382.0775 0.8 56146 24010 3 2382.071957 795.0331 Pre-mRNA 3'-end-processing factor FIP1 OS=Homo sapiens OX=9606 GN=FIP1L1 PE=1 SV=1 4.23 3772 - 656015 - - - -2.3446 - 2.233 0.379 - 74.2 1 2 0 -0.0056 20 0 0 0 7.85E+06 9.80E+06 - - - 4.7129 1 221125_WJC_METTL3_EV_vs_WT_F04.24011.24011.3 9.91E-07 17/64 R.EGSPLDIPVDVFVHQSK.L "sp|Q6ZN17|LN28B_HUMAN,tr|A0A1B0GTK2|A0A1B0GTK2_HUMAN,tr|A0A1B0GVD3|A0A1B0GVD3_HUMAN" 3 1865.9523 1.21 56147 24011 3 1865.95511 622.9914 Protein lin-28 homolog B OS=Homo sapiens OX=9606 GN=LIN28B PE=1 SV=1 4.54 3772.1 - 567589 - - - 1.4904 - 2.841 0.536 - 378.7 1 2 0 0.0028 17 0 0 0 7.93E+06 6.53E+06 - - - 7.153 0.9994 221125_WJC_METTL3_EV_vs_WT_F04.24013.24013.2 4.27E-06 15/34 R.IGPYQPNVPVGIDYVIPK[136.11].T "sp|P43243|MATR3_HUMAN,tr|B3KM87|B3KM87_HUMAN,tr|A8MXP9|A8MXP9_HUMAN,tr|A0A0R4J2E8|A0A0R4J2E8_HUMAN" 4 1976.0863 1.41 56149 24013 2 1976.09196 989.0504 Matrin-3 OS=Homo sapiens OX=9606 GN=MATR3 PE=1 SV=2 5.83 3772.4 - 315735 - - - 2.8895 - 2.201 0.503 - 414.2 1 2 0 0.0057 18 0 0 0 9.58E+06 6.80E+06 - - - 4.6939 1 221125_WJC_METTL3_EV_vs_WT_F04.24017.24017.3 2.06E-14 15/104 S.SC[160.03]YSFGSGGGYGSSFGGVDGLLAGGEK.A "sp|Q04695|K1C17_HUMAN,tr|K7EPJ9|K7EPJ9_HUMAN" 2 2572.1176 999 56151 24017 3 2572.121356 858.3798 "Keratin, type I cytoskeletal 17 OS=Homo sapiens OX=9606 GN=KRT17 PE=1 SV=2" 4.37 3772.9 - 575847 - - - 1.4474 - 3.229 0.76 - 210.1 1 1 0 0.0037 27 0 0 0 4.11E+06 0.00E+00 - - - 9.709 1 221125_WJC_METTL3_EV_vs_WT_F04.24018.24018.3 4.39E-17 29/104 R.ALYDAELSQMQTHISDTSVVLSMDNNR.N "sp|P48668|K2C6C_HUMAN,sp|P04259|K2C6B_HUMAN,sp|P02538|K2C6A_HUMAN" 3 3037.4121 452.91 56152 24018 3 3037.413867 1013.478 "Keratin, type II cytoskeletal 6C OS=Homo sapiens OX=9606 GN=KRT6C PE=1 SV=3" 4.22 3773 - 1.40E+06 - - - 0.5817 - 5.327 0.719 - 959.1 1 2 0 0.0018 27 0 0 0 3.32E+08 7.33E+05 - - - 10.4041 1 221125_WJC_METTL3_EV_vs_WT_F04.24019.24019.4 1.38E-11 28/186 R.VVYGGGAAEISC[160.03]ALAVSQEADK[136.11]C[160.03]PTLEQYAMR[166.11].A "sp|P48643|TCPE_HUMAN,tr|E9PCA1|E9PCA1_HUMAN,tr|B7ZAR1|B7ZAR1_HUMAN,tr|E7ENZ3|E7ENZ3_HUMAN" 4 3461.6384 0.61 56153 24019 4 3461.638704 866.4169 T-complex protein 1 subunit epsilon OS=Homo sapiens OX=9606 GN=CCT5 PE=1 SV=1 4.41 3773.1 - 966293 - - - 0.0786 - 5.533 0.651 - 380.6 1 2 1 0.0003 32 0 0 0 4.39E+06 7.15E+06 - - - 5.4088 1 221125_WJC_METTL3_EV_vs_WT_F04.24020.24020.3 9.02E-13 25/88 R.GSPQSAAAELSSGLLASAAASSR.A sp|Q12948|FOXC1_HUMAN 1 2088.0447 0.72 56154 24020 3 2088.048796 697.0222 Forkhead box protein C1 OS=Homo sapiens OX=9606 GN=FOXC1 PE=1 SV=3 6 3773.3 - 651037 - - - 1.9497 - 4.075 0.605 - 607.6 1 2 0 0.0041 23 0 0 0 1.15E+07 1.59E+07 - - - 8.5798 1 221125_WJC_METTL3_EV_vs_WT_F04.24023.24023.3 1.17E-12 18/112 K.VSDSISAQYPVVDHEFDAVVVGAGGAGLR.A "sp|P31040|SDHA_HUMAN,tr|A0A087X1I3|A0A087X1I3_HUMAN,tr|D6RFM5|D6RFM5_HUMAN,tr|A0A494C1T6|A0A494C1T6_HUMAN" 4 2914.4461 0.59 56157 24023 3 2914.448597 972.4893 "Succinate dehydrogenase [ubiquinone] flavoprotein subunit, mitochondrial OS=Homo sapiens OX=9606 GN=SDHA PE=1 SV=2" 4.22 3773.7 - 453632 - - - 0.8564 - 3.614 0.585 - 203.1 1 2 0 0.0025 29 0 0 0 9.43E+06 1.60E+07 - - - 8.0174 1 221125_WJC_METTL3_EV_vs_WT_F04.24026.24026.4 3.95E-05 12/156 R.ALYDAELSQMQTHISDTSVVLSMDNNR.N "sp|P48668|K2C6C_HUMAN,sp|P04259|K2C6B_HUMAN,sp|P02538|K2C6A_HUMAN" 3 3037.4121 14.98 56158 24026 4 3037.41114 760.3603 "Keratin, type II cytoskeletal 6C OS=Homo sapiens OX=9606 GN=KRT6C PE=1 SV=3" 4.22 3774.1 - 2.48E+06 - - - -0.3161 - 2.115 0.485 - 61.9 1 2 0 -0.001 27 0 0 0 8.04E+07 5.37E+06 - - - 3.6815 1 221125_WJC_METTL3_EV_vs_WT_F04.24028.24028.3 1.26E-09 18/84 K.FR[166.11]ISLGLPVGAVINC[160.03]ADNTGAK[136.11].N "sp|P62829|RL23_HUMAN,tr|J3KT29|J3KT29_HUMAN,tr|B9ZVP7|B9ZVP7_HUMAN,tr|C9JD32|C9JD32_HUMAN" 4 2290.2223 1.29 56160 24028 3 2290.223715 764.4147 60S ribosomal protein L23 OS=Homo sapiens OX=9606 GN=RPL23 PE=1 SV=1 8.22 3774.3 - 978923 - - - 0.6366 - 3.12 0.626 - 326.7 1 2 1 0.0015 22 0 0 0 1.28E+07 9.92E+06 - - - 8.2165 1 221125_WJC_METTL3_EV_vs_WT_F04.24036.24036.3 1.14E-10 28/108 K.RGGGSVVIVSSIAAFSPSPGFSPYNVSK.T "sp|Q6PKH6|DR4L2_HUMAN,sp|Q9BTZ2|DHRS4_HUMAN,tr|A0A087WSZ6|A0A087WSZ6_HUMAN,tr|A0A087WXI8|A0A087WXI8_HUMAN,tr|H0YKN3|H0YKN3_HUMAN" 5 2766.4341 1.89 56166 24036 3 2766.441397 923.152 Dehydrogenase\reductase SDR family member 4-like 2 OS=Homo sapiens OX=9606 GN=DHRS4L2 PE=2 SV=2 9.99 3775.5 - 857970 - - - 2.6449 - 4.986 0.676 - 861 1 2 0 0.0073 28 0 0 0 1.82E+07 9.62E+06 - - - 9.771 1 221125_WJC_METTL3_EV_vs_WT_F04.24037.24037.3 2.44E-14 27/112 K.VSDSISAQYPVVDHEFDAVVVGAGGAGLR[166.11].A "sp|P31040|SDHA_HUMAN,tr|A0A087X1I3|A0A087X1I3_HUMAN,tr|D6RFM5|D6RFM5_HUMAN,tr|A0A494C1T6|A0A494C1T6_HUMAN" 4 2924.4544 0.6 56167 24037 3 2924.452693 975.8254 "Succinate dehydrogenase [ubiquinone] flavoprotein subunit, mitochondrial OS=Homo sapiens OX=9606 GN=SDHA PE=1 SV=2" 4.22 3775.6 - 730470 - - - -0.5738 - 4.699 0.707 - 712 1 2 0 -0.0017 29 0 0 0 9.89E+06 1.64E+07 - - - 9.9818 1 221125_WJC_METTL3_EV_vs_WT_F04.24038.24038.3 1.60E-15 22/76 K.SYSMIVNNLLK[136.11]PISVEGSSK[136.11].K sp|Q9HB71|CYBP_HUMAN 1 2181.1686 0.3 56168 24038 3 2181.174007 728.0635 Calcyclin-binding protein OS=Homo sapiens OX=9606 GN=CACYBP PE=1 SV=2 8.22 3775.8 - 1.22E+06 - - - 2.4762 - 4.084 0.71 - 335.8 1 2 0 0.0054 20 0 0 0 6.72E+06 2.24E+07 - - - 9.8679 1 221125_WJC_METTL3_EV_vs_WT_F04.24039.24039.4 6.37E-07 22/126 K.LSELSNSQQSVQTLSLWLIHHR.K "sp|Q96P16|RPR1A_HUMAN,sp|Q9NQG5|RPR1B_HUMAN,tr|E9PIQ9|E9PIQ9_HUMAN,tr|E9PQF3|E9PQF3_HUMAN,tr|A0A0C4DGQ6|A0A0C4DGQ6_HUMAN,tr|K7EQR8|K7EQR8_HUMAN" 6 2575.3507 1.81 56169 24039 4 2575.354791 644.8449 Regulation of nuclear pre-mRNA domain-containing protein 1A OS=Homo sapiens OX=9606 GN=RPRD1A PE=1 SV=1 6.92 3775.9 - 927112 - - - 1.5947 - 4.057 0.588 - 421.5 1 2 0 0.0041 22 0 0 0 4.39E+07 2.43E+07 - - - 4.801 0.9995 221125_WJC_METTL3_EV_vs_WT_F04.24040.24040.3 1.61E-06 16/80 K.DLNTFLHEPFSSVAATC[160.03]QTPK.L sp|Q9H1E1|RNAS7_HUMAN 1 2362.1263 3.28 56170 24040 3 2362.137504 788.3827 Ribonuclease 7 OS=Homo sapiens OX=9606 GN=RNASE7 PE=1 SV=2 5.32 3776 - 921005 - - - 4.7233 - 3.412 0.434 - 210.6 1 2 0 0.0112 21 0 0 0 1.16E+07 3.53E+06 - - - 6.318 1 221125_WJC_METTL3_EV_vs_WT_F04.24041.24041.3 3.40E-14 26/108 K.R[166.11]GGGSVVIVSSIAAFSPSPGFSPYNVSK[136.11].T "sp|Q6PKH6|DR4L2_HUMAN,sp|Q9BTZ2|DHRS4_HUMAN,tr|A0A087WSZ6|A0A087WSZ6_HUMAN,tr|A0A087WXI8|A0A087WXI8_HUMAN,tr|H0YKN3|H0YKN3_HUMAN" 5 2784.4565 1.89 56171 24041 3 2784.463707 929.1595 Dehydrogenase\reductase SDR family member 4-like 2 OS=Homo sapiens OX=9606 GN=DHRS4L2 PE=2 SV=2 9.99 3776.1 - 857371 - - - 2.5703 - 4.911 0.722 - 755.7 1 2 0 0.0072 28 0 0 0 1.82E+07 9.62E+06 - - - 10.249 0.9995 221125_WJC_METTL3_EV_vs_WT_F04.24042.24042.4 1.61E-05 19/132 R.VSVGIHK[136.11]EDIDAAIETYNLLSER[166.11].W sp|P23921|RIR1_HUMAN 1 2589.3405 0.56 56172 24042 4 2589.345376 648.3424 Ribonucleoside-diphosphate reductase large subunit OS=Homo sapiens OX=9606 GN=RRM1 PE=1 SV=1 4.5 3776.3 - 661853 - - - 1.8765 - 3.461 0.416 - 222.9 1 2 1 0.0049 23 0 0 0 3.26E+06 5.84E+06 - - - 3.2478 1 221125_WJC_METTL3_EV_vs_WT_F04.24043.24043.3 6.98E-09 17/68 K.GHVDILAPTVQELAALEK.E "sp|Q92499|DDX1_HUMAN,tr|A0A7I2V2M5|A0A7I2V2M5_HUMAN,tr|A0A087X2G1|A0A087X2G1_HUMAN,tr|A0A7I2V430|A0A7I2V430_HUMAN,tr|A0A7I2V4F0|A0A7I2V4F0_HUMAN,tr|A0A087WZ71|A0A087WZ71_HUMAN,tr|A0A7I2YQ77|A0A7I2YQ77_HUMAN" 7 1903.0415 1.15 56173 24043 3 1903.041184 635.3544 ATP-dependent RNA helicase DDX1 OS=Homo sapiens OX=9606 GN=DDX1 PE=1 SV=2 4.65 3776.4 - 557457 - - - -0.1545 - 3.477 0.562 - 481.6 1 2 0 -0.0003 18 0 0 0 5.33E+06 4.63E+06 - - - 7.9088 1 221125_WJC_METTL3_EV_vs_WT_F04.24044.24044.3 5.76E-09 19/68 R.EGNDLYHEMIESGVINLK.D "sp|P06576|ATPB_HUMAN,tr|F8W079|F8W079_HUMAN,tr|H0YI37|H0YI37_HUMAN,tr|F8W0P7|F8W0P7_HUMAN,tr|H0YH81|H0YH81_HUMAN" 5 2059.9885 1.62 56174 24044 3 2059.990863 687.6701 "ATP synthase subunit beta, mitochondrial OS=Homo sapiens OX=9606 GN=ATP5F1B PE=1 SV=3" 4.4 3776.5 - 507233 - - - 1.1685 - 3.24 0.62 - 397.1 1 2 0 0.0024 18 0 0 0 4.53E+07 2.81E+07 - - - 8.379 0.9999 221125_WJC_METTL3_EV_vs_WT_F04.24045.24045.3 3.61E-10 14/68 K.GHVDILAPTVQELAALEK[136.11].E "sp|Q92499|DDX1_HUMAN,tr|A0A7I2V2M5|A0A7I2V2M5_HUMAN,tr|A0A087X2G1|A0A087X2G1_HUMAN,tr|A0A7I2V430|A0A7I2V430_HUMAN,tr|A0A7I2V4F0|A0A7I2V4F0_HUMAN,tr|A0A087WZ71|A0A087WZ71_HUMAN,tr|A0A7I2YQ77|A0A7I2YQ77_HUMAN" 7 1911.0557 1.15 56175 24045 3 1911.061728 638.0258 ATP-dependent RNA helicase DDX1 OS=Homo sapiens OX=9606 GN=DDX1 PE=1 SV=2 4.65 3776.7 - 430861 - - - 3.1658 - 3.583 0.557 - 268.8 1 2 0 0.006 18 0 0 0 5.33E+06 4.63E+06 - - - 7.9262 1 221125_WJC_METTL3_EV_vs_WT_F04.24047.24047.2 8.15E-16 17/40 K.RIDTPSLEEPSDLEELEQFAK.T "sp|P14859|PO2F1_HUMAN,tr|A0A0C4DG88|A0A0C4DG88_HUMAN" 2 2445.1911 13.42 56177 24047 2 2445.195889 1223.6028 "POU domain, class 2, transcription factor 1 OS=Homo sapiens OX=9606 GN=POU2F1 PE=1 SV=2" 4 3776.9 - 401203 - - - 1.9524 - 3.771 0.713 - 386.5 1 2 0 0.0048 21 0 0 0 2.12E+06 1.58E+05 - - - 7.569 0.9999 221125_WJC_METTL3_EV_vs_WT_F04.24048.24048.3 1.29E-05 16/56 K.SLQSELDEINK[136.11]ELSR[166.11].L "sp|Q16625|OCLN_HUMAN,tr|A0A0G2JMZ8|A0A0G2JMZ8_HUMAN" 2 1777.9177 1.39 56178 24048 3 1777.920115 593.6465 Occludin OS=Homo sapiens OX=9606 GN=OCLN PE=1 SV=1 4.41 3777.1 - 299672 - - - 1.3707 - 2.986 0.566 - 260.4 1 2 1 0.0024 15 0 0 0 3.16E+06 2.28E+06 - - - 7.7041 1 221125_WJC_METTL3_EV_vs_WT_F04.24052.24052.3 1.91E-05 14/56 R.NIETIINTFHQYSVK.L sp|P06702|S10A9_HUMAN 1 1805.9312 85.39 56180 24052 3 1805.932301 602.9843 Protein S100-A9 OS=Homo sapiens OX=9606 GN=S100A9 PE=1 SV=1 6.75 3777.6 - 4.27E+06 - - - 0.6102 - 2.555 0.448 - 192.8 1 2 0 0.0011 15 0 0 0 7.04E+07 8.25E+05 - - - 5.9822 1 221125_WJC_METTL3_EV_vs_WT_F04.24054.24054.3 8.32E-09 15/68 R.EGNDLYHEMIESGVINLK[136.11].D "sp|P06576|ATPB_HUMAN,tr|F8W079|F8W079_HUMAN,tr|H0YI37|H0YI37_HUMAN,tr|F8W0P7|F8W0P7_HUMAN,tr|H0YH81|H0YH81_HUMAN" 5 2068.0027 1.62 56182 24054 3 2068.003687 690.3415 "ATP synthase subunit beta, mitochondrial OS=Homo sapiens OX=9606 GN=ATP5F1B PE=1 SV=3" 4.4 3777.8 - 2.08E+06 - - - 0.4985 - 2.741 0.616 - 254.5 1 2 0 0.001 18 0 0 0 4.52E+07 2.79E+07 - - - 7.9183 1 221125_WJC_METTL3_EV_vs_WT_F04.24061.24061.3 0.000122 22/60 K.QNDQVSFASLVEELKK.V "sp|Q86UP2|KTN1_HUMAN,tr|G3V4Y7|G3V4Y7_HUMAN,tr|G3V5G2|G3V5G2_HUMAN,tr|H0YJZ8|H0YJZ8_HUMAN" 4 1833.9472 2.25 56187 24061 3 1833.948647 612.323 Kinectin OS=Homo sapiens OX=9606 GN=KTN1 PE=1 SV=1 4.68 3778.7 - 1.68E+06 - - - 0.7656 - 3.643 0.593 - 650.2 1 2 0 0.0014 16 0 0 0 1.96E+07 8.70E+06 - - - 8.4681 1 221125_WJC_METTL3_EV_vs_WT_F04.24064.24064.3 7.79E-13 28/100 R.VELSEQQLQLWPSDVDK[136.11]LSPTDNLPR[166.11].G sp|P09543|CN37_HUMAN 1 3024.5523 4.75 56190 24064 3 3024.554443 1009.1914 "2',3'-cyclic-nucleotide 3'-phosphodiesterase OS=Homo sapiens OX=9606 GN=CNP PE=1 SV=2" 4.11 3779.1 - 723728 - - - 0.7082 - 4.678 0.617 - 908.8 1 2 1 0.0021 26 0 0 0 3.26E+07 6.86E+06 - - - 8.9679 1 221125_WJC_METTL3_EV_vs_WT_F04.24065.24065.2 6.73E-14 19/52 R.ALYDAELSQMQTHISDTSVVLSMDNNR.N "sp|P48668|K2C6C_HUMAN,sp|P04259|K2C6B_HUMAN,sp|P02538|K2C6A_HUMAN" 3 3037.4121 -1 56191 24065 2 3037.417835 1519.7133 "Keratin, type II cytoskeletal 6C OS=Homo sapiens OX=9606 GN=KRT6C PE=1 SV=3" 4.22 3779.2 - 708747 - - - 1.8881 - 3.866 0.758 - 712.7 1 2 0 0.0057 27 0 0 0 0.00E+00 0.00E+00 - - - 7.9623 1 221125_WJC_METTL3_EV_vs_WT_F04.24066.24066.4 0.000115 18/114 K.DHSPDLYSLELAGLDEIGKR.Y "sp|O75787|RENR_HUMAN,tr|B7Z413|B7Z413_HUMAN,tr|A0A1B0GTU8|A0A1B0GTU8_HUMAN,tr|A0A1B0GVI9|A0A1B0GVI9_HUMAN,tr|B7Z1I9|B7Z1I9_HUMAN,tr|A0A1B0GVC7|A0A1B0GVC7_HUMAN,tr|H7C3E1|H7C3E1_HUMAN,tr|A0A1B0GU12|A0A1B0GU12_HUMAN,tr|A0A1C7CYW4|A0A1C7CYW4_HUMAN,tr|A0A1B0GWD6|A0A1B0GWD6_HUMAN,tr|A0A1B0GVB9|A0A1B0GVB9_HUMAN,tr|A0A1B0GWJ8|A0A1B0GWJ8_HUMAN,tr|A0A1B0GVW0|A0A1B0GVW0_HUMAN,tr|A0A1B0GTB0|A0A1B0GTB0_HUMAN" 14 2227.1121 1.93 56192 24066 4 2227.112668 557.7853 Renin receptor OS=Homo sapiens OX=9606 GN=ATP6AP2 PE=1 SV=2 4.43 3779.3 - 675606 - - - 0.2654 - 3.556 0.573 - 356.1 1 2 0 0.0006 20 0 0 0 4.39E+06 2.27E+06 - - - 4.6374 1 221125_WJC_METTL3_EV_vs_WT_F04.24067.24067.3 1.42E-13 22/124 K.HAPTYTIPLSPVLSPTLPAEAPTAQVPPSLPR.N sp|Q9NPI6|DCP1A_HUMAN 1 3317.8024 7.9 56193 24067 3 3317.813369 1106.9414 mRNA-decapping enzyme 1A OS=Homo sapiens OX=9606 GN=DCP1A PE=1 SV=3 6.75 3779.4 - 569914 - - - 3.317 - 4.163 0.67 - 282.8 1 2 0 0.011 32 0 0 0 5.83E+06 7.38E+05 - - - 9.288 1 221125_WJC_METTL3_EV_vs_WT_F04.24069.24069.2 3.17E-07 15/28 R.NIETIINTFHQYSVK.L sp|P06702|S10A9_HUMAN 1 1805.9312 999 56195 24069 2 1805.936207 903.9729 Protein S100-A9 OS=Homo sapiens OX=9606 GN=S100A9 PE=1 SV=1 6.75 3779.7 - 484337 - - - 2.7731 - 2.92 0.552 - 612.9 1 2 0 0.005 15 0 0 0 7.40E+06 0.00E+00 - - - 5.751 1 221125_WJC_METTL3_EV_vs_WT_F04.24071.24071.3 1.04E-08 24/108 K.SGDAAIVDMVPGK[136.11]PMC[160.03]VESFSDYPPLGR[166.11].F "sp|P68104|EF1A1_HUMAN,sp|Q5VTE0|EF1A3_HUMAN,tr|A0A7I2V659|A0A7I2V659_HUMAN,tr|A0A087WVQ9|A0A087WVQ9_HUMAN" 4 3012.415 0.11 56196 24071 3 3012.415547 1005.1456 Elongation factor 1-alpha 1 OS=Homo sapiens OX=9606 GN=EEF1A1 PE=1 SV=1 4.23 3779.9 - 1.56E+06 - - - 0.1746 - 3.821 0.656 - 507.8 1 2 0 0.0005 28 0 0 0 6.28E+07 5.95E+08 - - - 8.9376 1 221125_WJC_METTL3_EV_vs_WT_F04.24074.24074.3 2.18E-14 21/92 Y.QAELSQMQTQISETNVILSMDNNR.S sp|P04264|K2C1_HUMAN 1 2749.3011 999 56198 24074 3 2749.306493 917.441 "Keratin, type II cytoskeletal 1 OS=Homo sapiens OX=9606 GN=KRT1 PE=1 SV=6" 4.14 3780.3 - 1.18E+06 - - - 1.9641 - 4.391 0.698 - 405.2 1 1 0 0.0054 24 0 0 0 7.80E+06 0.00E+00 - - - 9.7569 1 221125_WJC_METTL3_EV_vs_WT_F04.24075.24075.3 2.09E-06 22/68 K.LQNELDNVSTLLEEAEK[136.11]K[136.11].G sp|P35580|MYH10_HUMAN 1 2088.0921 1.06 56199 24075 3 2088.098281 697.038 Myosin-10 OS=Homo sapiens OX=9606 GN=MYH10 PE=1 SV=3 4.25 3780.4 - 3.56E+06 - - - 2.9458 - 4.202 0.585 - 618.8 1 2 0 0.0062 18 0 0 0 4.57E+07 4.30E+07 - - - 8.6352 0.9999 221125_WJC_METTL3_EV_vs_WT_F04.24077.24077.4 2.04E-06 20/138 K.AQQGIVFLDEVDKIGSVPGIHQLR.D sp|O76031|CLPX_HUMAN 1 2618.418 1.85 56201 24077 4 2618.42151 655.6118 "ATP-dependent Clp protease ATP-binding subunit clpX-like, mitochondrial OS=Homo sapiens OX=9606 GN=CLPX PE=1 SV=2" 5.38 3780.6 - 1.08E+06 - - - 1.3268 - 3.886 0.574 - 153.5 1 2 1 0.0035 24 0 0 0 7.36E+06 3.98E+06 - - - 4.6568 1 221125_WJC_METTL3_EV_vs_WT_F04.24078.24078.3 5.06E-12 23/100 R.ERLEQQVPVNQVFGQDEMIDVIGVTK.G "sp|P39023|RL3_HUMAN,tr|G5E9G0|G5E9G0_HUMAN,tr|H7C3M2|H7C3M2_HUMAN,tr|B5MCW2|B5MCW2_HUMAN,tr|H7C422|H7C422_HUMAN" 5 2970.5121 0.95 56202 24078 3 2970.517114 991.178 60S ribosomal protein L3 OS=Homo sapiens OX=9606 GN=RPL3 PE=1 SV=2 4.18 3780.7 - 1.05E+06 - - - 1.6974 - 4.749 0.62 - 357.4 1 2 1 0.005 26 0 0 0 1.47E+07 1.54E+07 - - - 9.0352 1 221125_WJC_METTL3_EV_vs_WT_F04.24080.24080.3 8.50E-07 21/76 K.HGAEHYWDLALSESVLESTD.- sp|O43395|PRPF3_HUMAN 1 2258.0128 - 56204 24080 3 2258.017609 753.6782 U4\U6 small nuclear ribonucleoprotein Prp3 OS=Homo sapiens OX=9606 GN=PRPF3 PE=1 SV=2 4.32 3780.9 - 902771 - - - 2.1488 - 3.477 0.571 - 476.2 1 2 0 0.0049 20 0 0 0 - - - - - 7.928 1 221125_WJC_METTL3_EV_vs_WT_F04.24081.24081.4 6.61E-06 16/90 K.FTEDLVGSVVHVLSHR[166.11].Q "sp|Q6P9B6|MEAK7_HUMAN,tr|H3BUB0|H3BUB0_HUMAN,tr|H3BM75|H3BM75_HUMAN" 3 1803.9507 0.21 56205 24081 4 1803.951055 451.995 MTOR-associated protein MEAK7 OS=Homo sapiens OX=9606 GN=MEAK7 PE=1 SV=2 5.99 3781.1 - 700759 - - - 0.1951 - 2.601 0.509 - 358.7 1 2 0 0.0004 16 0 0 0 9.35E+05 4.39E+06 - - - 3.993 1 221125_WJC_METTL3_EV_vs_WT_F04.24082.24082.4 4.14E-11 19/132 K.NELHNLLDKPQLQGIPVLVLGNK.R "sp|Q96BM9|ARL8A_HUMAN,sp|Q9NVJ2|ARL8B_HUMAN" 2 2551.4486 1.41 56206 24082 4 2551.455855 638.8694 ADP-ribosylation factor-like protein 8A OS=Homo sapiens OX=9606 GN=ARL8A PE=1 SV=1 6.75 3781.2 - 632392 - - - 2.8403 - 3.409 0.654 - 329.8 1 2 0 0.0072 23 0 0 0 1.02E+07 7.22E+06 - - - 5.3138 0.9997 221125_WJC_METTL3_EV_vs_WT_F04.24083.24083.4 1.28E-09 23/138 K.AQQGIVFLDEVDK[136.11]IGSVPGIHQLR[166.11].D sp|O76031|CLPX_HUMAN 1 2636.4405 1.85 56207 24083 4 2636.449554 660.1174 "ATP-dependent Clp protease ATP-binding subunit clpX-like, mitochondrial OS=Homo sapiens OX=9606 GN=CLPX PE=1 SV=2" 5.38 3781.3 - 595778 - - - 3.4319 - 3.57 0.578 - 261.3 1 2 1 0.009 24 0 0 0 7.36E+06 3.98E+06 - - - 4.6629 1 221125_WJC_METTL3_EV_vs_WT_F04.24086.24086.3 1.15E-05 Nov-52 R.TESDDLHTFLLEIK.E "sp|P35658|NU214_HUMAN,tr|A0A0A0MSW3|A0A0A0MSW3_HUMAN,tr|A0A494BZU9|A0A494BZU9_HUMAN,tr|A0A494C1F2|A0A494C1F2_HUMAN" 4 1659.8356 1.6 56210 24086 3 1659.835767 554.2858 Nuclear pore complex protein Nup214 OS=Homo sapiens OX=9606 GN=NUP214 PE=1 SV=2 4.31 3781.7 - 496318 - - - 0.1205 - 2.522 0.542 - 104.5 1 2 0 0.0002 14 0 0 0 5.82E+06 3.63E+06 - - - 7.0411 1 221125_WJC_METTL3_EV_vs_WT_F04.24089.24089.3 1.50E-09 18/56 R.EGSEEDLDALEHMFR.Q sp|P31944|CASPE_HUMAN 1 1776.7625 999 56212 24089 3 1776.766186 593.2614 Caspase-14 OS=Homo sapiens OX=9606 GN=CASP14 PE=1 SV=2 4.08 3782.1 - 899423 - - - 2.0864 - 3.497 0.675 - 635.3 1 2 0 0.0037 15 0 0 0 9.72E+06 0.00E+00 - - - 9.3312 0.9999 221125_WJC_METTL3_EV_vs_WT_F04.24092.24092.3 7.21E-08 20/72 K.ETLIAEIEELDR[166.11]QNQEATK[136.11].H "sp|Q15643|TRIPB_HUMAN,tr|H0YJ97|H0YJ97_HUMAN" 2 2247.1349 1.22 56214 24092 3 2247.135585 750.0523 Thyroid receptor-interacting protein 11 OS=Homo sapiens OX=9606 GN=TRIP11 PE=1 SV=3 4.14 3782.4 - 2.00E+06 - - - 0.2866 - 3.851 0.438 - 396.5 1 2 1 0.0006 19 0 0 0 5.47E+07 4.50E+07 - - - 6.7357 1 221125_WJC_METTL3_EV_vs_WT_F04.24094.24094.3 1.24E-13 23/68 K.LQNELDNVSTLLEEAEKK.G sp|P35580|MYH10_HUMAN 1 2072.0637 1.06 56216 24094 3 2072.067864 691.6952 Myosin-10 OS=Homo sapiens OX=9606 GN=MYH10 PE=1 SV=3 4.25 3782.5 - 4.49E+06 - - - 1.9951 - 4.493 0.631 - 688.9 1 2 0 0.0041 18 0 0 0 4.57E+07 4.30E+07 - - - 9.3153 0.9951 221125_WJC_METTL3_EV_vs_WT_F04.24095.24095.4 1.66E-05 20/120 K.K[136.11]LLHHLSDLALTLPTDAVSIC[160.03].L "sp|Q86U44|MTA70_HUMAN,tr|B4E349|B4E349_HUMAN,tr|F5H6D8|F5H6D8_HUMAN,tr|H0YFV6|H0YFV6_HUMAN,tr|B4DTN4|B4DTN4_HUMAN" 5 2324.2654 0.02 56217 24095 4 2324.268744 582.0736 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 5.98 3782.6 - 1.69E+06 - - - 1.4585 - 3.123 0.493 - 169.2 1 1 0 0.0034 21 0 0 0 1.61E+06 7.91E+07 - - - 3.8927 0.9999 221125_WJC_METTL3_EV_vs_WT_F04.24099.24099.3 2.83E-09 20/100 K.ADLESESFRPNLSDPSELLLPDQIEK.L sp|Q8N573|OXR1_HUMAN 1 2941.4557 0.51 56221 24099 3 2941.465104 981.4925 Oxidation resistance protein 1 OS=Homo sapiens OX=9606 GN=OXR1 PE=1 SV=2 3.95 3783.1 - 426993 - - - 3.2096 - 3.062 0.617 - 223.8 1 2 0 0.0094 26 0 0 0 4.71E+06 9.26E+06 - - - 7.9909 0.9999 221125_WJC_METTL3_EV_vs_WT_F04.24100.24100.3 5.91E-05 Nov-68 K.GFFDPNTHENLTYVQLLR.R "sp|P58107|EPIPL_HUMAN,sp|P58107|EPIPL_HUMAN,sp|P58107|EPIPL_HUMAN,sp|P58107|EPIPL_HUMAN,tr|A0A075B730|A0A075B730_HUMAN,tr|A0A075B730|A0A075B730_HUMAN,tr|A0A075B730|A0A075B730_HUMAN,tr|A0A075B730|A0A075B730_HUMAN" 8 2163.0749 4.34 56222 24100 3 2163.075595 722.0322 Epiplakin OS=Homo sapiens OX=9606 GN=EPPK1 PE=1 SV=3 5.32 3783.2 - 403750 - - - 0.3199 - 2.069 0.414 - 99 1 2 0 0.0007 18 0 0 0 4.55E+06 1.05E+06 - - - 4.966 0.9999 221125_WJC_METTL3_EV_vs_WT_F04.24101.24101.3 0.0218 15/52 K.AQIHDLVLVGGSTR[166.11].L "sp|P0DMV8|HS71A_HUMAN,sp|P0DMV9|HS71B_HUMAN,tr|V9GZ37|V9GZ37_HUMAN,tr|A0A0G2JIW1|A0A0G2JIW1_HUMAN" 4 1474.8131 0.98 56223 24101 3 1474.814006 492.6117 Heat shock 70 kDa protein 1A OS=Homo sapiens OX=9606 GN=HSPA1A PE=1 SV=1 6.79 3783.4 - 362630 - - - 0.5831 - 2.812 0.402 - 266.2 1 2 0 0.0009 14 0 0 0 3.38E+06 3.45E+06 - - - 5.7693 1 221125_WJC_METTL3_EV_vs_WT_F04.24102.24102.4 2.26E-09 15/102 R.SPSELFAQHIVTIVHHVK.E "sp|Q9Y2W1|TR150_HUMAN,tr|A0A3B3ITZ9|A0A3B3ITZ9_HUMAN" 2 2041.1109 2.9 56224 24102 4 2041.114151 511.285 Thyroid hormone receptor-associated protein 3 OS=Homo sapiens OX=9606 GN=THRAP3 PE=1 SV=2 6.78 3783.5 - 277162 - - - 1.5952 - 2.791 0.594 - 143.2 1 2 0 0.0033 18 0 0 0 5.40E+06 1.86E+06 - - - 4.7469 0.9988 221125_WJC_METTL3_EV_vs_WT_F04.24106.24106.3 1.43E-09 16/84 K.KEEQVISLGPQVAEGENVFGVC[160.03].H "sp|P62263|RS14_HUMAN,tr|A0A2R8Y811|A0A2R8Y811_HUMAN,tr|E5RH77|E5RH77_HUMAN" 3 2388.1631 1.26 56226 24106 3 2388.16565 797.0617 40S ribosomal protein S14 OS=Homo sapiens OX=9606 GN=RPS14 PE=1 SV=3 4.09 3784 - 1.33E+06 - - - 1.0569 - 3.241 0.618 - 154 1 1 0 0.0025 22 0 0 0 2.33E+07 1.84E+07 - - - 8.2172 0.8652 221125_WJC_METTL3_EV_vs_WT_F04.24107.24107.3 0.000118 18/56 R.K[136.11]HAASDVDLEIESLL.N "sp|Q86U44|MTA70_HUMAN,tr|F5H6D8|F5H6D8_HUMAN,tr|H0YFV6|H0YFV6_HUMAN,tr|B4DTN4|B4DTN4_HUMAN" 4 1646.8607 0.05 56227 24107 3 1647.861138 549.9608 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 4.31 3784.1 - 941554 - - - 607.5019 - 3.128 0.46 - 437.2 1 1 0 1.0005 15 0 0 0 1.10E+06 2.20E+07 - - - 6.3671 1 221125_WJC_METTL3_EV_vs_WT_F04.24108.24108.3 3.62E-06 15/64 R.TQLEELEDELQATEDAK[136.11].L "sp|P35580|MYH10_HUMAN,sp|P35749|MYH11_HUMAN,sp|P35579|MYH9_HUMAN" 3 1968.9255 1.51 56228 24108 3 1968.926952 657.3158 Myosin-10 OS=Homo sapiens OX=9606 GN=MYH10 PE=1 SV=3 3.71 3784.2 - 730358 - - - 0.7319 - 3.334 0.555 - 325.2 1 2 0 0.0014 17 0 0 0 8.01E+06 5.29E+06 - - - 7.7694 1 221125_WJC_METTL3_EV_vs_WT_F04.24109.24109.4 4.50E-14 26/204 R.GPSPRPPATAYDAPASAFGSSLLGSGGSAFAPPLR.A sp|Q8WUF5|IASPP_HUMAN 1 3326.6684 0.33 56229 24109 4 3326.67296 832.6744 RelA-associated inhibitor OS=Homo sapiens OX=9606 GN=PPP1R13L PE=1 SV=4 8.75 3784.4 - 693499 - - - 1.3737 - 4.203 0.688 - 274.3 1 2 0 0.0046 35 0 0 0 4.22E+06 1.28E+07 - - - 5.6387 1 221125_WJC_METTL3_EV_vs_WT_F04.24111.24111.3 8.31E-12 19/88 K.NELHNLLDKPQLQGIPVLVLGNK.R "sp|Q96BM9|ARL8A_HUMAN,sp|Q9NVJ2|ARL8B_HUMAN" 2 2551.4486 1.4 56231 24111 3 2551.457214 851.4901 ADP-ribosylation factor-like protein 8A OS=Homo sapiens OX=9606 GN=ARL8A PE=1 SV=1 6.75 3784.6 - 372930 - - - 3.373 - 3.893 0.729 - 383.8 1 2 0 0.0086 23 0 0 0 1.57E+06 1.12E+06 - - - 9.8538 1 221125_WJC_METTL3_EV_vs_WT_F04.24116.24116.3 6.48E-13 21/104 K.VLYDAEISQIHQSVTDTNVILSMDNSR.N sp|P35908|K22E_HUMAN 1 3047.487 131.22 56234 24116 3 3047.488029 1016.8363 "Keratin, type II cytoskeletal 2 epidermal OS=Homo sapiens OX=9606 GN=KRT2 PE=1 SV=2" 4.22 3785.4 - 1.91E+06 - - - 0.3442 - 4.834 0.676 - 288.7 1 2 0 0.001 27 0 0 0 9.03E+07 6.88E+05 - - - 9.7015 0.9989 221125_WJC_METTL3_EV_vs_WT_F04.24119.24119.3 1.00E-09 15/84 K.K[136.11]EEQVISLGPQVAEGENVFGVC[160.03].H "sp|P62263|RS14_HUMAN,tr|A0A2R8Y811|A0A2R8Y811_HUMAN,tr|E5RH77|E5RH77_HUMAN" 3 2396.1773 1.38 56237 24119 3 2396.178322 799.7331 40S ribosomal protein S14 OS=Homo sapiens OX=9606 GN=RPS14 PE=1 SV=3 4.09 3785.8 - 990532 - - - 0.4157 - 3.203 0.618 - 122.1 1 1 0 0.001 22 0 0 0 2.33E+07 1.68E+07 - - - 8.1897 1 221125_WJC_METTL3_EV_vs_WT_F04.24120.24120.3 1.52E-12 25/96 R.GAGYTFGQDISETFNHANGLTLVSR[166.11].A "sp|P67775|PP2AA_HUMAN,sp|P62714|PP2AB_HUMAN,tr|H0YC23|H0YC23_HUMAN" 3 2664.2808 0.79 56238 24120 3 2664.278514 889.1009 Serine\threonine-protein phosphatase 2A catalytic subunit alpha isoform OS=Homo sapiens OX=9606 GN=PPP2CA PE=1 SV=1 5.32 3785.9 - 927246 - - - -0.8445 - 5.302 0.675 - 925.6 1 2 0 -0.0022 25 0 0 0 2.65E+07 3.34E+07 - - - 9.9026 1 221125_WJC_METTL3_EV_vs_WT_F04.24122.24122.3 6.90E-08 16/68 K.LQVELDNVTGLLSQSDSK[136.11].S sp|P35579|MYH9_HUMAN 1 1953.0146 1.3 56240 24122 3 1953.014809 652.0121 Myosin-9 OS=Homo sapiens OX=9606 GN=MYH9 PE=1 SV=4 4.03 3786.2 - 640355 - - - 0.1065 - 3.229 0.507 - 420.1 1 2 0 0.0002 18 0 0 0 6.76E+06 5.18E+06 - - - 7.1113 1 221125_WJC_METTL3_EV_vs_WT_F04.24124.24124.3 3.91E-12 25/96 R.GAGYTFGQDISETFNHANGLTLVSR.A "sp|P67775|PP2AA_HUMAN,sp|P62714|PP2AB_HUMAN,tr|H0YC23|H0YC23_HUMAN" 3 2654.2725 0.79 56242 24124 3 2654.274439 885.7648 Serine\threonine-protein phosphatase 2A catalytic subunit alpha isoform OS=Homo sapiens OX=9606 GN=PPP2CA PE=1 SV=1 5.32 3786.4 - 566631 - - - 0.7328 - 4.994 0.709 - 848.2 1 2 0 0.0019 25 0 0 0 2.65E+07 3.34E+07 - - - 10.1441 1 221125_WJC_METTL3_EV_vs_WT_F04.24125.24125.2 1.13E-08 17/30 K.K[136.11]VSQEILELLNTTTAK[136.11].E "sp|Q86U44|MTA70_HUMAN,tr|H0YFV6|H0YFV6_HUMAN" 2 1803.0324 0.001 56243 24125 2 1803.030213 902.5235 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 6.14 3786.6 - 437676 - - - -1.2296 - 3.624 0.656 - 684.2 1 2 0 -0.0022 16 0 0 0 0.00E+00 4.97E+06 - - - 7.0511 0.8918 221125_WJC_METTL3_EV_vs_WT_F04.24126.24126.3 1.2 Jun-84 R.LPIGNTIQPSQAATFMNDAIEK.A sp|O43395|PRPF3_HUMAN 1 2358.1889 2.54 56244 24126 3 2358.185272 787.0703 U4\U6 small nuclear ribonucleoprotein Prp3 OS=Homo sapiens OX=9606 GN=PRPF3 PE=1 SV=2 4.37 3786.7 - 298810 - - - -1.5584 - 1.396 0.15 - 30.1 9 2 0 -0.0037 22 0 0 0 5.64E+06 2.22E+06 - - - 0.5606 0.9999 221125_WJC_METTL3_EV_vs_WT_F04.24128.24128.3 2.28E-05 Nov-44 R.LFPPQWIC[160.03]C[160.03]DIR[166.11].Y sp|Q86U44|MTA70_HUMAN 1 1613.7722 0.01 56246 24128 3 1613.769307 538.9313 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 5.82 3787 - 261481 - - - -1.7989 - 2.086 0.523 - 134.3 1 2 0 -0.0029 12 0 0 0 1.18E+05 9.16E+06 - - - 6.4081 0.8724 221125_WJC_METTL3_EV_vs_WT_F04.24132.24132.3 0.0181 Aug-92 R.DTEPGPASGGTLGPSGEEAPRPR[166.11]M.S "sp|Q765P7|MTSS2_HUMAN,tr|A0A087WXN9|A0A087WXN9_HUMAN" 2 2375.1051 - 56248 24132 3 2375.099105 792.709 Protein MTSS 2 OS=Homo sapiens OX=9606 GN=MTSS2 PE=1 SV=1 4.41 3787.5 - 587650 - - - -2.527 - 1.9 0.337 - 40.5 1 1 0 -0.006 24 0 0 0 - - - - - 3.7863 0.9999 221125_WJC_METTL3_EV_vs_WT_F04.24134.24134.3 2.82E-09 16/68 K.LQVELDNVTGLLSQSDSK.S sp|P35579|MYH9_HUMAN 1 1945.0004 1.46 56250 24134 3 1945.006139 649.3407 Myosin-9 OS=Homo sapiens OX=9606 GN=MYH9 PE=1 SV=4 4.03 3787.8 - 657174 - - - 2.9501 - 2.915 0.544 - 381.9 1 2 0 0.0057 18 0 0 0 8.17E+06 5.61E+06 - - - 7.2676 0.9997 221125_WJC_METTL3_EV_vs_WT_F04.24135.24135.2 2.65E-06 26-Dec R.HEILQWVLQTDSQQ.- sp|Q96AG4|LRC59_HUMAN 1 1723.8529 - 56251 24135 2 1723.857379 862.9338 Leucine-rich repeat-containing protein 59 OS=Homo sapiens OX=9606 GN=LRRC59 PE=1 SV=1 4.35 3787.9 - 532828 - - - 2.5698 - 2.667 0.517 - 616.5 1 2 0 0.0044 14 0 0 0 - - - - - 5.3198 0.9515 221125_WJC_METTL3_EV_vs_WT_F04.24136.24136.2 0.1 28-Sep R.K[136.11]HAASDVDLEIESLL.N "sp|Q86U44|MTA70_HUMAN,tr|F5H6D8|F5H6D8_HUMAN,tr|H0YFV6|H0YFV6_HUMAN,tr|B4DTN4|B4DTN4_HUMAN" 4 1646.8607 0.04 56252 24136 2 1646.860824 824.4376 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 4.31 3788 - 329292 - - - 0.0953 - 1.613 0.312 - 152.5 1 1 0 0.0002 15 0 0 0 2.89E+05 6.93E+06 - - - 2.5208 1 221125_WJC_METTL3_EV_vs_WT_F04.24138.24138.4 8.99E-09 19/144 R.GAGYTFGQDISETFNHANGLTLVSR[166.11].A "sp|P67775|PP2AA_HUMAN,sp|P62714|PP2AB_HUMAN,tr|H0YC23|H0YC23_HUMAN" 3 2664.2808 0.65 56254 24138 4 2664.28414 667.0775 Serine\threonine-protein phosphatase 2A catalytic subunit alpha isoform OS=Homo sapiens OX=9606 GN=PPP2CA PE=1 SV=1 5.32 3788.3 - 299237 - - - 1.2671 - 3.608 0.584 - 298.7 1 2 0 0.0034 25 0 0 0 1.80E+06 2.78E+06 - - - 4.7164 1 221125_WJC_METTL3_EV_vs_WT_F04.24143.24143.4 5.02E-08 15/156 K.VLYDAEISQIHQSVTDTNVILSMDNSR.N sp|P35908|K22E_HUMAN 1 3047.487 89.79 56257 24143 4 3047.492432 762.879 "Keratin, type II cytoskeletal 2 epidermal OS=Homo sapiens OX=9606 GN=KRT2 PE=1 SV=2" 4.22 3788.8 - 5.44E+06 - - - 1.789 - 2.66 0.567 - 81.3 1 2 0 0.0055 27 0 0 0 4.99E+07 5.56E+05 - - - 4.4658 1 221125_WJC_METTL3_EV_vs_WT_F04.24144.24144.3 3.26E-09 17/60 K.K[136.11]VSQEILELLNTTTAK[136.11].E "sp|Q86U44|MTA70_HUMAN,tr|H0YFV6|H0YFV6_HUMAN" 2 1803.0324 0 56258 24144 3 1803.033504 602.0181 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 6.14 3788.9 - 3.17E+06 - - - 0.5957 - 3.315 0.576 - 477.4 1 2 0 0.0011 16 0 0 0 7.65E+04 4.88E+07 - - - 8.0366 1 221125_WJC_METTL3_EV_vs_WT_F04.24146.24146.4 3.04E-08 20/138 R.AYNYVAQEVDDYHAFQTLTHIYNK[136.11].V sp|Q9NYU2|UGGG1_HUMAN 1 2910.3704 0.27 56260 24146 4 2910.37374 728.5999 UDP-glucose:glycoprotein glucosyltransferase 1 OS=Homo sapiens OX=9606 GN=UGGT1 PE=1 SV=3 5.21 3789.1 - 1.55E+06 - - - 1.1397 - 4.169 0.601 - 220.2 1 2 0 0.0033 24 0 0 0 2.53E+06 9.20E+06 - - - 4.9144 1 221125_WJC_METTL3_EV_vs_WT_F04.24151.24151.3 6.15E-07 18/88 R.QGGDVLQNEEGETTSHLMGMFYR.T "sp|P39748|FEN1_HUMAN,tr|F5H1Y3|F5H1Y3_HUMAN" 2 2598.1479 0.41 56265 24151 3 2598.152311 867.0566 Flap endonuclease 1 OS=Homo sapiens OX=9606 GN=FEN1 PE=1 SV=1 4.4 3789.7 - 265007 - - - 1.7028 - 3.225 0.638 - 285.4 1 2 0 0.0044 23 0 0 0 2.62E+06 6.37E+06 - - - 8.3988 0.9987 221125_WJC_METTL3_EV_vs_WT_F04.24161.24161.3 2.45E-08 13/60 A.KDFGNYLFNFASAATK.K sp|Q96A49|SYAP1_HUMAN 1 1792.8784 1.43 56273 24161 3 1792.877195 598.6334 Synapse-associated protein 1 OS=Homo sapiens OX=9606 GN=SYAP1 PE=1 SV=1 8.5 3791.2 - 348627 - - - -0.6916 - 2.782 0.595 - 217.2 1 1 0 -0.0012 16 0 0 0 3.39E+06 2.36E+06 - - - 7.7986 0.997 221125_WJC_METTL3_EV_vs_WT_F04.24163.24163.3 1.05E-07 13/60 A.K[136.11]DFGNYLFNFASAATK[136.11].K sp|Q96A49|SYAP1_HUMAN 1 1808.9068 1.43 56275 24163 3 1808.904664 603.9762 Synapse-associated protein 1 OS=Homo sapiens OX=9606 GN=SYAP1 PE=1 SV=1 8.5 3791.4 - 669135 - - - -1.2002 - 2.949 0.483 - 136.1 1 1 0 -0.0022 16 0 0 0 3.39E+06 2.36E+06 - - - 6.6993 1 221125_WJC_METTL3_EV_vs_WT_F04.24166.24166.3 5.12E-09 22/104 K.NFQNIFPPSATLHLSNIPPSVSEEDLK[136.11].V "sp|P26599|PTBP1_HUMAN,tr|A0A0U1RRM4|A0A0U1RRM4_HUMAN,tr|A6NLN1|A6NLN1_HUMAN,tr|A0A0D9SF20|A0A0D9SF20_HUMAN,tr|A0A7I2V621|A0A7I2V621_HUMAN" 5 3001.5277 1.25 56277 24166 3 3001.529092 1001.5165 Polypyrimidine tract-binding protein 1 OS=Homo sapiens OX=9606 GN=PTBP1 PE=1 SV=1 4.65 3791.8 - 2.35E+06 - - - 0.4798 - 3.331 0.578 - 243.9 1 2 0 0.0014 27 0 0 0 5.29E+07 4.24E+07 - - - 7.752 1 221125_WJC_METTL3_EV_vs_WT_F04.24168.24168.3 1.46E-06 25/80 R.SKLEDIANAALAASAVTQVAK.V "sp|Q8WVM8|SCFD1_HUMAN,tr|A0A7I2V4U2|A0A7I2V4U2_HUMAN,tr|A0A7I2V4B8|A0A7I2V4B8_HUMAN,tr|H0YIZ7|H0YIZ7_HUMAN,tr|J3KNG4|J3KNG4_HUMAN,tr|A0A7I2V5Z4|A0A7I2V5Z4_HUMAN,tr|A0A7I2V3C9|A0A7I2V3C9_HUMAN,tr|A0A7I2V5I2|A0A7I2V5I2_HUMAN,tr|A0A7I2V590|A0A7I2V590_HUMAN,tr|G3V5E2|G3V5E2_HUMAN,tr|H0YJY1|H0YJY1_HUMAN,tr|A0A7I2YQR2|A0A7I2YQR2_HUMAN,tr|A0A7I2V362|A0A7I2V362_HUMAN,tr|A0A7I2V320|A0A7I2V320_HUMAN,tr|A0A7I2V534|A0A7I2V534_HUMAN,tr|A0A7I2V3B4|A0A7I2V3B4_HUMAN,tr|G3V2M8|G3V2M8_HUMAN,tr|A0A7I2V5H5|A0A7I2V5H5_HUMAN,tr|A0A7I2V4R0|A0A7I2V4R0_HUMAN,tr|A0A7I2V5R9|A0A7I2V5R9_HUMAN,tr|A0A7I2YQQ1|A0A7I2YQQ1_HUMAN,tr|A0A7I2V5L2|A0A7I2V5L2_HUMAN,tr|A0A7I2V321|A0A7I2V321_HUMAN" 23 2070.1321 1.57 56278 24168 3 2070.138126 691.0513 Sec1 family domain-containing protein 1 OS=Homo sapiens OX=9606 GN=SCFD1 PE=1 SV=4 5.79 3792 - 1.55E+06 - - - 2.9187 - 4.919 0.56 - 1001.7 1 2 1 0.006 21 0 0 0 1.69E+07 1.08E+07 - - - 8.6012 1 221125_WJC_METTL3_EV_vs_WT_F04.24170.24170.4 7.22E-14 30/174 R.IKEELIAQGLLESEDRPAEDSEDEVLAELR.K sp|O75528|TADA3_HUMAN 1 3395.6944 1.32 56280 24170 4 3395.697316 849.9309 Transcriptional adapter 3 OS=Homo sapiens OX=9606 GN=TADA3 PE=1 SV=1 3.96 3792.2 - 1.11E+06 - - - 0.8617 - 4.812 0.747 - 439.4 1 2 1 0.0029 30 0 0 0 5.80E+06 4.40E+06 - - - 6.2078 0.9999 221125_WJC_METTL3_EV_vs_WT_F04.24172.24172.3 3.49E-06 16/56 R.DYKVDQEIINIMQDR.L "sp|O96000|NDUBA_HUMAN,tr|H3BV16|H3BV16_HUMAN" 2 1878.9146 0.76 56282 24172 3 1878.916086 627.3121 NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 10 OS=Homo sapiens OX=9606 GN=NDUFB10 PE=1 SV=3 4.23 3792.5 - 755339 - - - 0.8106 - 2.745 0.471 - 398.9 1 2 1 0.0015 15 0 0 0 2.43E+07 3.21E+07 - - - 6.4257 1 221125_WJC_METTL3_EV_vs_WT_F04.24173.24173.4 4.29E-06 13/108 R.TDGALLVNAMFFK[136.11]PHWDEK[136.11].F "sp|P50454|SERPH_HUMAN,tr|E9PPV6|E9PPV6_HUMAN,tr|E9PR70|E9PR70_HUMAN,tr|E9PMI5|E9PMI5_HUMAN,tr|E9PJH8|E9PJH8_HUMAN,tr|E9PK86|E9PK86_HUMAN" 6 2234.1165 1.31 56283 24173 4 2234.118814 559.5364 Serpin H1 OS=Homo sapiens OX=9606 GN=SERPINH1 PE=1 SV=2 5.35 3792.6 - 509359 - - - 1.0308 - 3.052 0.491 - 124.4 1 2 0 0.0023 19 0 0 0 3.05E+06 2.33E+06 - - - 3.8765 0.9999 221125_WJC_METTL3_EV_vs_WT_F04.24174.24174.3 4.68E-11 13/96 K.GSPGLLDPC[160.03]EKDPFDTLATMTDQQR.E sp|Q96KR1|ZFR_HUMAN 1 2791.2793 0.17 56284 24174 3 2791.277182 931.4337 Zinc finger RNA-binding protein OS=Homo sapiens OX=9606 GN=ZFR PE=1 SV=2 4.04 3792.7 - 357684 - - - -0.757 - 2.612 0.647 - 105.4 1 2 1 -0.0021 25 0 0 0 2.23E+06 1.29E+07 - - - 7.9617 0.9999 221125_WJC_METTL3_EV_vs_WT_F04.24179.24179.3 9.25E-08 17/120 R.SETPPVPPPPPYLASYPGFPENGAPGPPISR.F sp|P48634|PRC2A_HUMAN 1 3184.587 2 56289 24179 3 3184.594365 1062.5363 Protein PRRC2A OS=Homo sapiens OX=9606 GN=PRRC2A PE=1 SV=3 4.53 3793.4 - 322638 - - - 2.3278 - 2.568 0.496 - 160.8 1 2 0 0.0074 31 0 0 0 1.41E+07 7.05E+06 - - - 6.2377 1 221125_WJC_METTL3_EV_vs_WT_F04.24188.24188.3 2.76E-10 25/104 K.NFQNIFPPSATLHLSNIPPSVSEEDLK.V "sp|P26599|PTBP1_HUMAN,tr|A0A0U1RRM4|A0A0U1RRM4_HUMAN,tr|A6NLN1|A6NLN1_HUMAN,tr|A0A0D9SF20|A0A0D9SF20_HUMAN,tr|A0A7I2V621|A0A7I2V621_HUMAN" 5 2993.5135 1.08 56296 24188 3 2993.521215 998.8451 Polypyrimidine tract-binding protein 1 OS=Homo sapiens OX=9606 GN=PTBP1 PE=1 SV=1 4.65 3794.4 - 2.54E+06 - - - 2.5933 - 4.249 0.64 - 421 1 2 0 0.0078 27 0 0 0 8.37E+07 7.77E+07 - - - 9.0015 1 221125_WJC_METTL3_EV_vs_WT_F04.24189.24189.3 1.33E-12 26/80 R.SK[136.11]LEDIANAALAASAVTQVAK[136.11].V "sp|Q8WVM8|SCFD1_HUMAN,tr|A0A7I2V4U2|A0A7I2V4U2_HUMAN,tr|A0A7I2V4B8|A0A7I2V4B8_HUMAN,tr|H0YIZ7|H0YIZ7_HUMAN,tr|J3KNG4|J3KNG4_HUMAN,tr|A0A7I2V5Z4|A0A7I2V5Z4_HUMAN,tr|A0A7I2V3C9|A0A7I2V3C9_HUMAN,tr|A0A7I2V5I2|A0A7I2V5I2_HUMAN,tr|A0A7I2V590|A0A7I2V590_HUMAN,tr|G3V5E2|G3V5E2_HUMAN,tr|H0YJY1|H0YJY1_HUMAN,tr|A0A7I2YQR2|A0A7I2YQR2_HUMAN,tr|A0A7I2V362|A0A7I2V362_HUMAN,tr|A0A7I2V320|A0A7I2V320_HUMAN,tr|A0A7I2V534|A0A7I2V534_HUMAN,tr|A0A7I2V3B4|A0A7I2V3B4_HUMAN,tr|G3V2M8|G3V2M8_HUMAN,tr|A0A7I2V5H5|A0A7I2V5H5_HUMAN,tr|A0A7I2V4R0|A0A7I2V4R0_HUMAN,tr|A0A7I2V5R9|A0A7I2V5R9_HUMAN,tr|A0A7I2YQQ1|A0A7I2YQQ1_HUMAN,tr|A0A7I2V5L2|A0A7I2V5L2_HUMAN,tr|A0A7I2V321|A0A7I2V321_HUMAN" 23 2086.1605 1.57 56297 24189 3 2086.164288 696.3941 Sec1 family domain-containing protein 1 OS=Homo sapiens OX=9606 GN=SCFD1 PE=1 SV=4 5.79 3794.5 - 1.34E+06 - - - 1.8234 - 5.155 0.611 - 1210.7 1 2 1 0.0038 21 0 0 0 1.69E+07 1.08E+07 - - - 9.2827 1 221125_WJC_METTL3_EV_vs_WT_F04.24190.24190.4 2.28E-10 16/156 K.YYAVNFPMRDGIDDESYGQIFKPIISK.V sp|Q92769|HDAC2_HUMAN 1 3165.5481 0.74 56298 24190 4 3165.556121 792.3943 Histone deacetylase 2 OS=Homo sapiens OX=9606 GN=HDAC2 PE=1 SV=2 4.68 3794.7 - 1.12E+06 - - - 2.5266 - 2.867 0.683 - 89.1 1 2 1 0.008 27 0 0 0 4.61E+06 6.19E+06 - - - 5.4982 1 221125_WJC_METTL3_EV_vs_WT_F04.24192.24192.3 1.02E-08 16/72 K.GTPEQPQC[160.03]GFSNAVVQILR.L sp|Q86SX6|GLRX5_HUMAN 1 2100.0422 0 56300 24192 3 2100.047451 701.0214 "Glutaredoxin-related protein 5, mitochondrial OS=Homo sapiens OX=9606 GN=GLRX5 PE=1 SV=2" 5.99 3794.9 - 993055 - - - 2.4895 - 2.868 0.629 - 249.9 1 2 0 0.0052 19 0 0 0 1.52E+07 8.38E+09 - - - 8.1398 0.9998 221125_WJC_METTL3_EV_vs_WT_F04.24197.24197.4 1.17E-05 12/174 R.IK[136.11]EELIAQGLLESEDR[166.11]PAEDSEDEVLAELR[166.11].K sp|O75528|TADA3_HUMAN 1 3423.7251 1.28 56305 24197 4 3423.731492 856.9386 Transcriptional adapter 3 OS=Homo sapiens OX=9606 GN=TADA3 PE=1 SV=1 3.96 3795.5 - 296273 - - - 1.8582 - 1.93 0.503 - 63.3 1 2 1 0.0064 30 0 0 0 5.96E+06 4.66E+06 - - - 3.8036 0.971 221125_WJC_METTL3_EV_vs_WT_F04.24198.24198.3 0.0189 Jul-64 R.ELESQISELQEDLESER.A sp|P35579|MYH9_HUMAN 1 2032.9437 1.35 56306 24198 3 2032.952067 678.6552 Myosin-9 OS=Homo sapiens OX=9606 GN=MYH9 PE=1 SV=4 3.77 3795.7 - 228347 - - - 4.1285 - 1.611 0.246 - 50.5 1 2 0 0.0084 17 0 0 0 2.23E+06 1.65E+06 - - - 2.485 0.9993 221125_WJC_METTL3_EV_vs_WT_F04.24199.24199.3 0.000259 Aug-64 K.RGSEGGVAAFVDFVDIK.S sp|Q96T58|MINT_HUMAN 1 1765.8999 0.92 56307 24199 3 1765.904465 589.6406 Msx2-interacting protein OS=Homo sapiens OX=9606 GN=SPEN PE=1 SV=1 4.56 3795.8 - 142916 - - - 2.5857 - 1.993 0.373 - 58.1 1 2 0 0.0046 17 0 0 0 1.83E+06 2.00E+06 - - - 4.4396 1 221125_WJC_METTL3_EV_vs_WT_F04.24208.24208.3 5.48E-12 16/76 K.AFEDWLNDDLGSYQGAQGNR[166.11].Y "sp|Q8N6T3|ARFG1_HUMAN,tr|F8VWH9|F8VWH9_HUMAN,tr|E5RHT6|E5RHT6_HUMAN,tr|F8W1U7|F8W1U7_HUMAN,tr|E5RHC5|E5RHC5_HUMAN" 5 2264.9962 1.73 56312 24208 3 2264.999136 756.006 ADP-ribosylation factor GTPase-activating protein 1 OS=Homo sapiens OX=9606 GN=ARFGAP1 PE=1 SV=2 3.84 3797 - 946814 - - - 1.2923 - 3.394 0.719 - 247.5 1 2 0 0.0029 20 0 0 0 1.65E+07 9.51E+06 - - - 9.52 0.9992 221125_WJC_METTL3_EV_vs_WT_F04.24210.24210.4 0.000335 13/156 K.NFQNIFPPSATLHLSNIPPSVSEEDLK.V "sp|P26599|PTBP1_HUMAN,tr|A0A0U1RRM4|A0A0U1RRM4_HUMAN,tr|A6NLN1|A6NLN1_HUMAN,tr|A0A0D9SF20|A0A0D9SF20_HUMAN,tr|A0A7I2V621|A0A7I2V621_HUMAN" 5 2993.5135 1.68 56314 24210 4 2993.52739 749.3856 Polypyrimidine tract-binding protein 1 OS=Homo sapiens OX=9606 GN=PTBP1 PE=1 SV=1 4.65 3797.3 - 600209 - - - 4.6561 - 2.627 0.443 - 88.1 1 2 0 0.0139 27 0 0 0 9.99E+06 5.93E+06 - - - 3.3802 0.9998 221125_WJC_METTL3_EV_vs_WT_F04.24212.24212.4 5.42E-07 13/108 K.IDGDK[136.11]DGFVTVDELK[136.11]DWIK[136.11].F sp|O43852|CALU_HUMAN 1 2216.1427 0.7 56316 24212 4 2216.147765 555.043 Calumenin OS=Homo sapiens OX=9606 GN=CALU PE=1 SV=2 4.17 3797.6 - 431749 - - - 2.2787 - 2.882 0.541 - 137.6 1 2 2 0.005 19 0 0 0 1.97E+06 2.83E+06 - - - 4.2915 0.9999 221125_WJC_METTL3_EV_vs_WT_F04.24213.24213.3 0.0136 15/108 R.YGSGQQPLILPQSIQLPPGQSLSVGAPR.R "sp|Q5JSZ5|PRC2B_HUMAN,tr|A0A804HKU3|A0A804HKU3_HUMAN,tr|A0A804HJR4|A0A804HJR4_HUMAN" 3 2887.5556 5.77 56317 24213 3 2887.563614 963.5258 Protein PRRC2B OS=Homo sapiens OX=9606 GN=PRRC2B PE=1 SV=2 8.75 3797.7 - 376635 - - - 2.7781 - 2.688 0.523 - 104.9 1 2 0 0.008 28 0 0 0 1.40E+07 2.43E+06 - - - 6.6436 1 221125_WJC_METTL3_EV_vs_WT_F04.24214.24214.3 6.29E-08 14/68 K.K[136.11]TGLSSEQTVNVLAQILK[136.11].R "sp|P35269|T2FA_HUMAN,tr|M0QXD6|M0QXD6_HUMAN" 2 1944.1226 0.52 56318 24214 3 1944.122708 649.0482 General transcription factor IIF subunit 1 OS=Homo sapiens OX=9606 GN=GTF2F1 PE=1 SV=2 8.59 3797.8 - 329731 - - - 0.0339 - 2.604 0.539 - 257.1 1 2 0 0.0001 18 0 0 0 3.49E+06 6.70E+06 - - - 6.9324 0.9998 221125_WJC_METTL3_EV_vs_WT_F04.24215.24215.3 2.94E-05 Dec-68 K.KTGLSSEQTVNVLAQILK.R "sp|P35269|T2FA_HUMAN,tr|M0QXD6|M0QXD6_HUMAN" 2 1928.0942 0.52 56319 24215 3 1928.098922 643.7054 General transcription factor IIF subunit 1 OS=Homo sapiens OX=9606 GN=GTF2F1 PE=1 SV=2 8.59 3798 - 269551 - - - 2.4273 - 2.339 0.415 - 116.1 1 2 0 0.0047 18 0 0 0 3.49E+06 6.70E+06 - - - 5.2814 1 221125_WJC_METTL3_EV_vs_WT_F04.24216.24216.3 3.19E-08 Nov-92 K.RVESIQC[160.03]FQNTEAGSPTIMLLSLK.A "sp|Q14527|HLTF_HUMAN,tr|H7C5K0|H7C5K0_HUMAN,tr|A0A0C4DGA6|A0A0C4DGA6_HUMAN" 3 2721.383 2.22 56320 24216 3 2721.382661 908.1349 Helicase-like transcription factor OS=Homo sapiens OX=9606 GN=HLTF PE=1 SV=2 6.14 3798.1 - 251143 - - - -0.1143 - 2.27 0.605 - 118.1 1 2 0 -0.0003 24 0 0 0 1.71E+06 7.70E+05 - - - 7.1891 0.9998 221125_WJC_METTL3_EV_vs_WT_F04.24217.24217.4 4.96E-05 11/102 K.EDLSWPGLAVGNLFHRPR.A "sp|O75787|RENR_HUMAN,tr|A0A1B0GTU8|A0A1B0GTU8_HUMAN,tr|B7Z1I9|B7Z1I9_HUMAN,tr|H7C3E1|H7C3E1_HUMAN,tr|A0A1B0GV24|A0A1B0GV24_HUMAN,tr|A0A1B0GUT7|A0A1B0GUT7_HUMAN,tr|A0A1C7CYW4|A0A1C7CYW4_HUMAN,tr|H7C240|H7C240_HUMAN,tr|A0A1B0GVB9|A0A1B0GVB9_HUMAN,tr|A0A1B0GWJ8|A0A1B0GWJ8_HUMAN,tr|A0A1B0GVW0|A0A1B0GVW0_HUMAN,tr|A0A1B0GW13|A0A1B0GW13_HUMAN,tr|A0A1B0GTB0|A0A1B0GTB0_HUMAN,tr|A0A1B0GV60|A0A1B0GV60_HUMAN" 14 2063.0701 1.42 56321 24217 4 2063.074797 516.7748 Renin receptor OS=Homo sapiens OX=9606 GN=ATP6AP2 PE=1 SV=2 6.85 3798.2 - 176987 - - - 2.2801 - 2.204 0.436 - 113.5 1 2 0 0.0047 18 0 0 0 3.91E+06 2.76E+06 - - - 3.2904 0.9994 221125_WJC_METTL3_EV_vs_WT_F04.24218.24218.3 0.000259 Aug-52 K.EISNLNQLIEEFKK.N "sp|Q14789|GOGB1_HUMAN,tr|E7EU81|E7EU81_HUMAN,tr|H0Y867|H0Y867_HUMAN" 3 1703.9094 1.42 56322 24218 3 1703.912798 568.9771 Golgin subfamily B member 1 OS=Homo sapiens OX=9606 GN=GOLGB1 PE=1 SV=2 4.79 3798.3 - 139232 - - - 1.9937 - 1.666 0.389 - 64.7 1 2 0 0.0034 14 0 0 0 2.00E+06 1.41E+06 - - - 4.2325 1 221125_WJC_METTL3_EV_vs_WT_F04.24223.24223.3 1.67E-10 18/76 K.AFEDWLNDDLGSYQGAQGNR.Y "sp|Q8N6T3|ARFG1_HUMAN,tr|F8VWH9|F8VWH9_HUMAN,tr|E5RHT6|E5RHT6_HUMAN,tr|F8W1U7|F8W1U7_HUMAN,tr|E5RHC5|E5RHC5_HUMAN" 5 2254.9879 1.73 56325 24223 3 2254.994432 752.6699 ADP-ribosylation factor GTPase-activating protein 1 OS=Homo sapiens OX=9606 GN=ARFGAP1 PE=1 SV=2 3.84 3798.9 - 1.92E+06 - - - 2.8794 - 3.574 0.626 - 212.3 1 2 0 0.0065 20 0 0 0 1.65E+07 9.51E+06 - - - 8.6075 0.9984 221125_WJC_METTL3_EV_vs_WT_F04.24225.24225.3 3.21E-07 19/56 K.LQDREWLTELFQQSK.V "sp|P78344|IF4G2_HUMAN,tr|E9PKF8|E9PKF8_HUMAN,tr|H0Y3P2|H0Y3P2_HUMAN,tr|H0YE22|H0YE22_HUMAN,tr|D3DQV9|D3DQV9_HUMAN" 5 1919.9741 1.77 56327 24225 3 1919.984816 640.9987 Eukaryotic translation initiation factor 4 gamma 2 OS=Homo sapiens OX=9606 GN=EIF4G2 PE=1 SV=1 4.68 3799.2 - 457496 - - - 5.5673 - 3.538 0.518 - 724.8 1 2 1 0.0107 15 0 0 0 2.02E+07 1.14E+07 - - - 7.6093 0.9998 221125_WJC_METTL3_EV_vs_WT_F04.24228.24228.4 0.00147 10/102 K.R[166.11]FDLGLEDVLIPHVDAGK[136.11].G sp|O60476|MA1A2_HUMAN 1 2011.0857 1.19 56330 24228 4 2011.087739 503.7787 "Mannosyl-oligosaccharide 1,2-alpha-mannosidase IB OS=Homo sapiens OX=9606 GN=MAN1A2 PE=1 SV=1" 4.66 3799.6 - 189781 - - - 0.991 - 1.69 0.403 - 58.8 1 2 0 0.002 18 0 0 0 1.06E+06 8.92E+05 - - - 2.9129 0.986 221125_WJC_METTL3_EV_vs_WT_F04.24231.24231.3 0.151 Jul-44 R.LSVEADINGLRR.V "sp|Q04695|K1C17_HUMAN,tr|F5GWP8|F5GWP8_HUMAN" 2 1341.7365 999 56333 24231 3 1341.741068 448.2528 "Keratin, type I cytoskeletal 17 OS=Homo sapiens OX=9606 GN=KRT17 PE=1 SV=2" 6.07 3800 - 109778 - - - 3.4329 - 1.503 0.266 - 96.4 1 2 0 0.0046 12 0 0 0 3.18E+06 0.00E+00 - - - 2.6338 0.9982 221125_WJC_METTL3_EV_vs_WT_F04.24235.24235.3 3.53E-06 19/80 K.K[136.11]LLHHLSDLALTLPTDAVSIC[160.03].L "sp|Q86U44|MTA70_HUMAN,tr|B4E349|B4E349_HUMAN,tr|F5H6D8|F5H6D8_HUMAN,tr|H0YFV6|H0YFV6_HUMAN,tr|B4DTN4|B4DTN4_HUMAN" 5 2324.2654 0.09 56335 24235 3 2324.26781 775.7624 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 5.98 3800.6 - 787950 - - - 1.0567 - 3.329 0.544 - 214.3 1 1 0 0.0025 21 0 0 0 1.30E+07 1.39E+08 - - - 7.4877 1 221125_WJC_METTL3_EV_vs_WT_F04.24239.24239.3 2.28E-09 17/92 K.YNDDSDDSYFTSSSSYFDEPVELR[166.11].S sp|Q9NP61|ARFG3_HUMAN 1 2847.1547 1.46 56339 24239 3 2847.159654 950.0588 ADP-ribosylation factor GTPase-activating protein 3 OS=Homo sapiens OX=9606 GN=ARFGAP3 PE=1 SV=1 3.57 3801.1 - 607807 - - - 1.7474 - 3.426 0.803 - 270.6 1 2 0 0.005 24 0 0 0 1.62E+07 1.11E+07 - - - 10.3513 1 221125_WJC_METTL3_EV_vs_WT_F04.24240.24240.3 6.60E-17 20/92 K.YNDDSDDSYFTSSSSYFDEPVELR.S sp|Q9NP61|ARFG3_HUMAN 1 2837.1464 1.46 56340 24240 3 2837.145412 946.7227 ADP-ribosylation factor GTPase-activating protein 3 OS=Homo sapiens OX=9606 GN=ARFGAP3 PE=1 SV=1 3.57 3801.2 - 585471 - - - -0.3514 - 3.843 0.858 - 416.5 1 2 0 -0.001 24 0 0 0 1.62E+07 1.11E+07 - - - 11.2324 1 221125_WJC_METTL3_EV_vs_WT_F04.24242.24242.3 1.44E-11 20/80 K.NSTPFMAEHLEETLSAVTNNR.Q "sp|Q9NRA8|4ET_HUMAN,tr|B1AKL4|B1AKL4_HUMAN,tr|B0QYZ7|B0QYZ7_HUMAN" 3 2360.1067 1.54 56342 24242 3 2360.100645 787.7095 Eukaryotic translation initiation factor 4E transporter OS=Homo sapiens OX=9606 GN=EIF4ENIF1 PE=1 SV=2 4.75 3801.5 - 509345 - - - -2.5545 - 3.999 0.691 - 449.4 1 2 0 -0.006 21 0 0 0 1.72E+08 1.12E+08 - - - 9.5653 0.9999 221125_WJC_METTL3_EV_vs_WT_F04.24244.24244.3 8.63E-07 17/64 R.TSFTQEQIEALEKEFER.T "sp|P26367|PAX6_HUMAN,tr|A0A1W2PQG7|A0A1W2PQG7_HUMAN,tr|A0A1W2PRS6|A0A1W2PRS6_HUMAN,tr|A0A1W2PPH0|A0A1W2PPH0_HUMAN,tr|D1KF47|D1KF47_HUMAN,tr|A0A1W2PRA4|A0A1W2PRA4_HUMAN,tr|A0A1W2PRA8|A0A1W2PRA8_HUMAN,tr|A0A1X7SBT0|A0A1X7SBT0_HUMAN,tr|E9PKM0|E9PKM0_HUMAN,tr|A0A1W2PP89|A0A1W2PP89_HUMAN,tr|A0A1W2PRW7|A0A1W2PRW7_HUMAN,tr|A0A1W2PRH6|A0A1W2PRH6_HUMAN,tr|A0A1W2PQL7|A0A1W2PQL7_HUMAN,tr|A0A1W2PSA8|A0A1W2PSA8_HUMAN,tr|A0A1W2PP27|A0A1W2PP27_HUMAN,tr|A0A1W2PQJ8|A0A1W2PQJ8_HUMAN,tr|A0A1W2PQG3|A0A1W2PQG3_HUMAN,tr|A0A1W2PSB5|A0A1W2PSB5_HUMAN,tr|A0A1W2PPN2|A0A1W2PPN2_HUMAN,tr|A0A1W2PPG3|A0A1W2PPG3_HUMAN,tr|A0A1W2PPJ2|A0A1W2PPJ2_HUMAN,tr|A0A1W2PQA8|A0A1W2PQA8_HUMAN,tr|A0A1W2PS91|A0A1W2PS91_HUMAN,tr|A0A1W2PRG3|A0A1W2PRG3_HUMAN,tr|A0A1W2PPM5|A0A1W2PPM5_HUMAN,tr|A0A1W2PNS7|A0A1W2PNS7_HUMAN,tr|B1B1I8|B1B1I8_HUMAN,tr|A0A1W2PRU4|A0A1W2PRU4_HUMAN,tr|B1B1I9|B1B1I9_HUMAN,tr|A0A1W2PQ31|A0A1W2PQ31_HUMAN,tr|A0A1W2PQM7|A0A1W2PQM7_HUMAN" 31 2084.0062 0.95 56344 24244 3 2084.004404 695.676 Paired box protein Pax-6 OS=Homo sapiens OX=9606 GN=PAX6 PE=1 SV=2 4.32 3801.7 - 354419 - - - -0.869 - 2.813 0.496 - 337.4 1 2 1 -0.0018 17 0 0 0 3.44E+06 3.62E+06 - - - 6.6822 0.9996 221125_WJC_METTL3_EV_vs_WT_F04.24247.24247.4 0.00458 10/102 K.EDLSWPGLAVGNLFHR[166.11]PR[166.11].A "sp|O75787|RENR_HUMAN,tr|A0A1B0GTU8|A0A1B0GTU8_HUMAN,tr|B7Z1I9|B7Z1I9_HUMAN,tr|H7C3E1|H7C3E1_HUMAN,tr|A0A1B0GV24|A0A1B0GV24_HUMAN,tr|A0A1B0GUT7|A0A1B0GUT7_HUMAN,tr|A0A1C7CYW4|A0A1C7CYW4_HUMAN,tr|H7C240|H7C240_HUMAN,tr|A0A1B0GVB9|A0A1B0GVB9_HUMAN,tr|A0A1B0GWJ8|A0A1B0GWJ8_HUMAN,tr|A0A1B0GVW0|A0A1B0GVW0_HUMAN,tr|A0A1B0GW13|A0A1B0GW13_HUMAN,tr|A0A1B0GTB0|A0A1B0GTB0_HUMAN,tr|A0A1B0GV60|A0A1B0GV60_HUMAN" 14 2083.0866 1.42 56346 24247 4 2083.08835 521.7789 Renin receptor OS=Homo sapiens OX=9606 GN=ATP6AP2 PE=1 SV=2 6.85 3802.1 - 260243 - - - 0.8243 - 2.112 0.343 - 66.1 1 2 0 0.0017 18 0 0 0 3.91E+06 2.76E+06 - - - 2.4671 0.9999 221125_WJC_METTL3_EV_vs_WT_F04.24250.24250.3 2.80E-07 22/56 K.LQDR[166.11]EWLTELFQQSK[136.11].V "sp|P78344|IF4G2_HUMAN,tr|E9PKF8|E9PKF8_HUMAN,tr|H0Y3P2|H0Y3P2_HUMAN,tr|H0YE22|H0YE22_HUMAN,tr|D3DQV9|D3DQV9_HUMAN" 5 1937.9966 1.8 56348 24250 3 1937.99664 647.0061 Eukaryotic translation initiation factor 4 gamma 2 OS=Homo sapiens OX=9606 GN=EIF4G2 PE=1 SV=1 4.68 3802.4 - 744610 - - - 0.0222 - 3.297 0.516 - 885.9 1 2 1 0 15 0 0 0 2.07E+07 1.15E+07 - - - 7.4059 1 221125_WJC_METTL3_EV_vs_WT_F04.24251.24251.3 3.21E-12 23/84 R.GKEDPWNSITSGALTGAVLAAR.S "sp|O60830|TI17B_HUMAN,tr|V9GYU0|V9GYU0_HUMAN,tr|V9GYS0|V9GYS0_HUMAN" 3 2213.144 1.04 56349 24251 3 2213.153348 738.722 Mitochondrial import inner membrane translocase subunit Tim17-B OS=Homo sapiens OX=9606 GN=TIMM17B PE=1 SV=1 6.07 3802.5 - 707377 - - - 4.2031 - 4.434 0.655 - 514.3 1 2 1 0.0093 22 0 0 0 1.04E+07 1.01E+07 - - - 9.3709 0.9999 221125_WJC_METTL3_EV_vs_WT_F04.24252.24252.3 9.23E-06 14/84 R.GK[136.11]EDPWNSITSGALTGAVLAAR[166.11].S "sp|O60830|TI17B_HUMAN,tr|V9GYU0|V9GYU0_HUMAN,tr|V9GYS0|V9GYS0_HUMAN" 3 2231.1665 1.04 56350 24252 3 2231.164512 744.7294 Mitochondrial import inner membrane translocase subunit Tim17-B OS=Homo sapiens OX=9606 GN=TIMM17B PE=1 SV=1 6.07 3802.7 - 633602 - - - -0.8982 - 3.005 0.57 - 173.4 1 2 1 -0.002 22 0 0 0 1.04E+07 1.01E+07 - - - 7.503 1 221125_WJC_METTL3_EV_vs_WT_F04.24253.24253.3 7.98E-14 18/120 K.GAVTSEALK[136.11]DPDVC[160.03]TDPVQLTTYAMGVNIYK[136.11].E sp|Q6P161|RM54_HUMAN 1 3371.66 0.41 56351 24253 3 3371.659465 1124.8939 "39S ribosomal protein L54, mitochondrial OS=Homo sapiens OX=9606 GN=MRPL54 PE=1 SV=1" 4.23 3802.8 - 551137 - - - -0.1572 - 3.702 0.735 - 240.9 1 2 1 -0.0005 31 0 0 0 2.25E+06 5.49E+06 - - - 9.7456 1 221125_WJC_METTL3_EV_vs_WT_F04.24258.24258.3 1.64E-14 34/108 K.LGVNNISGIEEVNMFTNQGTVIHFNNPK.V "sp|P20290|BTF3_HUMAN,tr|A0A7I2V3T6|A0A7I2V3T6_HUMAN,tr|A0A7I2YQL2|A0A7I2YQL2_HUMAN" 3 3085.5291 1.04 56354 24258 3 3085.523555 1029.517 Transcription factor BTF3 OS=Homo sapiens OX=9606 GN=BTF3 PE=1 SV=1 5.4 3803.4 - 7.80E+06 - - - -1.8033 - 5.911 0.624 - 1280.4 1 2 0 -0.0056 28 0 0 0 1.16E+08 1.11E+08 - - - 9.5833 1 221125_WJC_METTL3_EV_vs_WT_F04.24259.24259.4 9.75E-14 29/162 K.LGVNNISGIEEVNMFTNQGTVIHFNNPK.V "sp|P20290|BTF3_HUMAN,tr|A0A7I2V3T6|A0A7I2V3T6_HUMAN,tr|A0A7I2YQL2|A0A7I2YQL2_HUMAN" 3 3085.5291 0.73 56355 24259 4 3085.529806 772.3896 Transcription factor BTF3 OS=Homo sapiens OX=9606 GN=BTF3 PE=1 SV=1 5.4 3803.5 - 2.92E+06 - - - 0.2227 - 5.584 0.692 - 590.3 1 2 0 0.0007 28 0 0 0 3.00E+07 4.11E+07 - - - 5.783 1 221125_WJC_METTL3_EV_vs_WT_F04.24260.24260.4 2.36E-06 19/114 K.TLSYLLPAIVHINHQPFLER.G "sp|P17844|DDX5_HUMAN,tr|A0A7I2V5F5|A0A7I2V5F5_HUMAN,tr|J3QRN5|J3QRN5_HUMAN,tr|A0A7I2V507|A0A7I2V507_HUMAN,tr|J3KTA4|J3KTA4_HUMAN,tr|A0A0G2JLI4|A0A0G2JLI4_HUMAN,tr|A0A7I2V2S0|A0A7I2V2S0_HUMAN,tr|J3QRQ7|J3QRQ7_HUMAN" 8 2360.3005 1.71 56356 24260 4 2360.298772 591.0824 Probable ATP-dependent RNA helicase DDX5 OS=Homo sapiens OX=9606 GN=DDX5 PE=1 SV=1 6.61 3803.6 - 1.84E+06 - - - -0.7266 - 2.848 0.513 - 183.1 1 2 0 -0.0017 20 0 0 0 3.03E+07 1.77E+07 - - - 4.0406 1 221125_WJC_METTL3_EV_vs_WT_F04.24265.24265.3 4.14E-11 19/80 K.NSTPFMAEHLEETLSAVTNNR[166.11].Q "sp|Q9NRA8|4ET_HUMAN,tr|B1AKL4|B1AKL4_HUMAN,tr|B0QYZ7|B0QYZ7_HUMAN" 3 2370.1149 1.54 56359 24265 3 2370.105168 791.0456 Eukaryotic translation initiation factor 4E transporter OS=Homo sapiens OX=9606 GN=EIF4ENIF1 PE=1 SV=2 4.75 3804.2 - 7.10E+06 - - - -4.1247 - 3.725 0.644 - 443.8 1 2 0 -0.0098 21 0 0 0 1.72E+08 1.12E+08 - - - 8.8701 0.9871 221125_WJC_METTL3_EV_vs_WT_F04.24269.24269.2 0.000167 Dec-36 R.R[166.11]AEQDSTTVAAFASSLVSG.L "sp|Q86U44|MTA70_HUMAN,tr|F5H6D8|F5H6D8_HUMAN,tr|H0YFV6|H0YFV6_HUMAN,tr|B4DTN4|B4DTN4_HUMAN" 4 1905.9308 0.01 56361 24269 2 1905.9293 953.9727 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 4.37 3804.7 - 1.40E+06 - - - -0.7634 - 2.106 0.436 - 183.8 1 1 0 -0.0015 19 0 0 0 2.39E+05 4.47E+07 - - - 4.0919 1 221125_WJC_METTL3_EV_vs_WT_F04.24275.24275.3 1.65E-11 34/108 K.LGVNNISGIEEVNMFTNQGTVIHFNNPK[136.11].V "sp|P20290|BTF3_HUMAN,tr|A0A7I2V3T6|A0A7I2V3T6_HUMAN,tr|A0A7I2YQL2|A0A7I2YQL2_HUMAN" 3 3093.5433 1.04 56365 24275 3 3093.533529 1032.1884 Transcription factor BTF3 OS=Homo sapiens OX=9606 GN=BTF3 PE=1 SV=1 5.4 3805.4 - 1.23E+07 - - - -3.1647 - 5.411 0.667 - 1205.8 1 2 0 -0.0098 28 0 0 0 1.16E+08 1.11E+08 - - - 9.8582 0.9976 221125_WJC_METTL3_EV_vs_WT_F04.24276.24276.4 1.63E-09 27/162 K.LGVNNISGIEEVNMFTNQGTVIHFNNPK[136.11].V "sp|P20290|BTF3_HUMAN,tr|A0A7I2V3T6|A0A7I2V3T6_HUMAN,tr|A0A7I2YQL2|A0A7I2YQL2_HUMAN" 3 3093.5433 0.7 56366 24276 4 3094.536527 774.3931 Transcription factor BTF3 OS=Homo sapiens OX=9606 GN=BTF3 PE=1 SV=1 5.4 3805.5 - 3.08E+06 - - - 321.0584 - 4.95 0.574 - 520.4 1 2 0 0.9932 28 0 0 0 3.06E+07 4.40E+07 - - - 4.4436 1 221125_WJC_METTL3_EV_vs_WT_F04.24277.24277.3 2.78E-06 17/56 K.VSQEILELLNTTTAK[136.11].E "sp|Q86U44|MTA70_HUMAN,tr|H0YFV6|H0YFV6_HUMAN" 2 1666.9233 0.03 56367 24277 3 1666.920095 556.6484 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 4.53 3805.5 - 1.78E+07 - - - -1.9029 - 3.294 0.529 - 455.9 1 2 0 -0.0032 15 0 0 0 4.93E+07 1.49E+09 - - - 7.5476 0.9995 221125_WJC_METTL3_EV_vs_WT_F04.24278.24278.4 2.96E-07 22/132 K.TYTAYVDLEK[136.11]DFAAEVVHPGDLK[136.11].N "sp|P54577|SYYC_HUMAN,tr|A0A6Q8PFX2|A0A6Q8PFX2_HUMAN" 2 2596.3032 0.69 56368 24278 4 2596.294314 650.0831 "Tyrosine--tRNA ligase, cytoplasmic OS=Homo sapiens OX=9606 GN=YARS1 PE=1 SV=4" 4.43 3805.7 - 2.30E+06 - - - -3.4168 - 3.331 0.505 - 130.1 1 2 1 -0.0089 23 0 0 0 3.80E+07 5.49E+07 - - - 4.0089 0.9998 221125_WJC_METTL3_EV_vs_WT_F04.24282.24282.4 2.65E-06 25/132 K.VFNTTPDDLDLHVIYDVSHNIAK[136.11].V sp|Q9Y3I0|RTCB_HUMAN 1 2633.3217 1.3 56370 24282 4 2633.316262 659.3377 RNA-splicing ligase RtcB homolog OS=Homo sapiens OX=9606 GN=RTCB PE=1 SV=1 4.54 3806.2 - 1.14E+06 - - - -2.0582 - 3.02 0.387 - 274.3 1 2 0 -0.0054 23 0 0 0 2.06E+08 1.58E+08 - - - 2.951 1 221125_WJC_METTL3_EV_vs_WT_F04.24305.24305.4 2.22E-09 26/132 K.VFNTTPDDLDLHVIYDVSHNIAK.V sp|Q9Y3I0|RTCB_HUMAN 1 2625.3075 1.3 56383 24305 4 2625.303395 657.3341 RNA-splicing ligase RtcB homolog OS=Homo sapiens OX=9606 GN=RTCB PE=1 SV=1 4.54 3808.8 - 2.71E+07 - - - -1.5568 - 4.202 0.591 - 390.7 1 2 0 -0.0041 23 0 0 0 2.06E+08 1.58E+08 - - - 4.834 1 221125_WJC_METTL3_EV_vs_WT_F04.24308.24308.3 8.00E-06 16/56 K.VSQEILELLNTTTAK.E "sp|Q86U44|MTA70_HUMAN,tr|H0YFV6|H0YFV6_HUMAN" 2 1658.9091 0.03 56385 24308 3 1658.905554 553.977 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 4.53 3809.2 - 1.30E+06 - - - -2.1177 - 2.93 0.523 - 438.9 1 2 0 -0.0035 15 0 0 0 4.93E+07 1.49E+09 - - - 7.175 1 221125_WJC_METTL3_EV_vs_WT_F04.24316.24316.3 1.70E-10 19/96 K.NIADLMTQAGVEELESENKIPATQK.S sp|O75506|HSBP1_HUMAN 1 2728.3589 1.26 56389 24316 3 2728.348587 910.4603 Heat shock factor-binding protein 1 OS=Homo sapiens OX=9606 GN=HSBP1 PE=1 SV=1 4.25 3810.1 - 5.36E+06 - - - -3.7895 - 4.026 0.651 - 230.4 1 2 1 -0.0103 25 0 0 0 2.91E+08 2.31E+08 - - - 8.9994 0.9999 221125_WJC_METTL3_EV_vs_WT_F04.24317.24317.3 1.04E-07 21/88 K.VFNTTPDDLDLHVIYDVSHNIAK[136.11].V sp|Q9Y3I0|RTCB_HUMAN 1 2633.3217 2.01 56390 24317 3 2633.311578 878.7812 RNA-splicing ligase RtcB homolog OS=Homo sapiens OX=9606 GN=RTCB PE=1 SV=1 4.54 3810.2 - 1.57E+06 - - - -3.837 - 3.429 0.532 - 406.8 1 2 0 -0.0101 23 0 0 0 5.91E+07 2.94E+07 - - - 7.3593 0.9993 221125_WJC_METTL3_EV_vs_WT_F04.24324.24324.3 3.13E-10 22/96 K.NIADLMTQAGVEELESENK[136.11]IPATQK[136.11].S sp|O75506|HSBP1_HUMAN 1 2744.3873 1.24 56393 24324 3 2744.378097 915.8031 Heat shock factor-binding protein 1 OS=Homo sapiens OX=9606 GN=HSBP1 PE=1 SV=1 4.25 3811.1 - 4.66E+06 - - - -3.3629 - 3.377 0.452 - 296.8 1 2 1 -0.0092 25 0 0 0 2.87E+08 2.31E+08 - - - 6.3766 1 221125_WJC_METTL3_EV_vs_WT_F04.24328.24328.3 1.83E-07 23/64 K.LNDLEDALQQAKEDLAR.L sp|P04264|K2C1_HUMAN 1 1940.9803 324.53 56395 24328 3 1940.976547 648.0007 "Keratin, type II cytoskeletal 1 OS=Homo sapiens OX=9606 GN=KRT1 PE=1 SV=6" 4.11 3811.6 - 4.54E+06 - - - -1.9511 - 4.516 0.575 - 897.1 1 2 1 -0.0038 17 0 0 0 4.38E+08 1.35E+06 - - - 8.7584 1 221125_WJC_METTL3_EV_vs_WT_F04.24332.24332.3 3.33E-11 24/100 K.DATNVGDEGGFAPNILENK[136.11]EGLELLK[136.11].T "sp|P06733|ENOA_HUMAN,tr|A0A2R8Y6G6|A0A2R8Y6G6_HUMAN" 2 2758.3996 2.47 56397 24332 3 2759.393453 920.4738 Alpha-enolase OS=Homo sapiens OX=9606 GN=ENO1 PE=1 SV=2 4.08 3812 - 3.42E+06 - - - 360.2988 - 4.167 0.689 - 550.1 1 2 1 0.9938 26 0 0 0 3.02E+08 1.22E+08 - - - 9.2298 1 221125_WJC_METTL3_EV_vs_WT_F04.24340.24340.3 2.94E-11 21/76 R.NQDLAPNSAEQASILSLVTK.L "sp|Q12905|ILF2_HUMAN,tr|B4DY09|B4DY09_HUMAN,tr|X6R6Z1|X6R6Z1_HUMAN,tr|A0A0A0MRL0|A0A0A0MRL0_HUMAN" 4 2098.0906 6.14 56402 24340 3 2099.099789 700.3708 Interleukin enhancer-binding factor 2 OS=Homo sapiens OX=9606 GN=ILF2 PE=1 SV=2 4.37 3812.9 - 3.54E+06 - - - 480.9973 - 3.581 0.647 - 693.4 1 2 0 1.0092 20 0 0 0 8.62E+07 1.40E+07 - - - 8.5686 0.9999 221125_WJC_METTL3_EV_vs_WT_F04.24346.24346.4 3.24E-08 24/144 K.NIADLMTQAGVEELESENKIPATQK.S sp|O75506|HSBP1_HUMAN 1 2728.3589 2.16 56406 24346 4 2728.35389 683.097 Heat shock factor-binding protein 1 OS=Homo sapiens OX=9606 GN=HSBP1 PE=1 SV=1 4.25 3813.6 - 3.83E+06 - - - -1.8458 - 3.755 0.56 - 273.7 1 2 1 -0.005 25 0 0 0 7.19E+07 3.33E+07 - - - 4.5197 1 221125_WJC_METTL3_EV_vs_WT_F04.24349.24349.3 1.33E-08 19/72 K.DVHEDSVTIFFENNWQSER.Q sp|P51116|FXR2_HUMAN 1 2351.0455 1.71 56409 24349 3 2351.040697 784.6891 Fragile X mental retardation syndrome-related protein 2 OS=Homo sapiens OX=9606 GN=FXR2 PE=1 SV=2 4.17 3814 - 1.47E+06 - - - -2.0234 - 3.695 0.658 - 603.5 1 2 0 -0.0048 19 0 0 0 1.89E+07 1.10E+07 - - - 9.0857 0.9995 221125_WJC_METTL3_EV_vs_WT_F04.24357.24357.3 2.02E-06 Nov-76 K.GNPQGFNQGLDC[160.03]DVIVAEVR[166.11].S sp|Q86U44|MTA70_HUMAN 1 2197.0461 0.13 56413 24357 3 2197.037014 733.356 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 4.03 3815 - 475879 - - - -4.1519 - 2.156 0.472 - 101.1 1 2 0 -0.0091 20 0 0 0 1.58E+06 1.23E+07 - - - 5.6636 1 221125_WJC_METTL3_EV_vs_WT_F04.24360.24360.2 5.81E-06 18/32 K.LNDLEDALQQAKEDLAR.L sp|P04264|K2C1_HUMAN 1 1940.9803 0.64 56415 24360 2 1940.976898 971.4974 "Keratin, type II cytoskeletal 1 OS=Homo sapiens OX=9606 GN=KRT1 PE=1 SV=6" 4.11 3815.3 - 626712 - - - -1.7702 - 3.607 0.618 - 940.9 1 2 1 -0.0034 17 0 0 0 1.64E+07 2.58E+07 - - - 6.7585 0.9998 221125_WJC_METTL3_EV_vs_WT_F04.24361.24361.4 2.75E-07 23/144 K.NIADLMTQAGVEELESENK[136.11]IPATQK[136.11].S sp|O75506|HSBP1_HUMAN 1 2744.3873 2.17 56416 24361 4 2744.379181 687.1041 Heat shock factor-binding protein 1 OS=Homo sapiens OX=9606 GN=HSBP1 PE=1 SV=1 4.25 3815.5 - 1.42E+06 - - - -2.9679 - 4.23 0.549 - 246.4 1 2 1 -0.0081 25 0 0 0 7.22E+07 3.33E+07 - - - 4.461 1 221125_WJC_METTL3_EV_vs_WT_F04.24362.24362.3 8.50E-09 18/80 K.K[136.11]GEPVSAEDLGVSGALTVLMK[136.11].D "sp|P11586|C1TC_HUMAN,tr|F5H2F4|F5H2F4_HUMAN,tr|V9GZ78|V9GZ78_HUMAN,tr|V9GYY3|V9GYY3_HUMAN,tr|A0A494C1T2|A0A494C1T2_HUMAN" 5 2116.1421 3.53 56417 24362 3 2116.14155 706.388 "C-1-tetrahydrofolate synthase, cytoplasmic OS=Homo sapiens OX=9606 GN=MTHFD1 PE=1 SV=4" 4.68 3815.6 - 989597 - - - -0.2396 - 3.285 0.522 - 337 1 2 0 -0.0005 21 0 0 0 6.31E+07 1.78E+07 - - - 7.2111 1 221125_WJC_METTL3_EV_vs_WT_F04.24372.24372.3 1.80E-09 19/92 K.QTQIFTTYSDNQPGVLIQVYEGER[166.11].A "sp|P0DMV8|HS71A_HUMAN,sp|P34931|HS71L_HUMAN,sp|P0DMV9|HS71B_HUMAN,tr|Q53FA3|Q53FA3_HUMAN,tr|V9GZ37|V9GZ37_HUMAN,tr|A0A0G2JIW1|A0A0G2JIW1_HUMAN" 6 2795.3642 0.18 56423 24372 3 2795.363348 932.7953 Heat shock 70 kDa protein 1A OS=Homo sapiens OX=9606 GN=HSPA1A PE=1 SV=1 4.14 3816.9 - 1.50E+06 - - - -0.2901 - 3.09 0.591 - 145.9 1 2 0 -0.0008 24 0 0 0 2.36E+08 1.29E+09 - - - 7.7491 1 221125_WJC_METTL3_EV_vs_WT_F04.24377.24377.4 1.21E-07 18/108 R.LNEQYEHASIHLWDLLEGK[136.11].E "sp|Q14444|CAPR1_HUMAN,tr|G3V153|G3V153_HUMAN" 2 2302.1473 0.97 56426 24377 4 2302.14144 576.5441 Caprin-1 OS=Homo sapiens OX=9606 GN=CAPRIN1 PE=1 SV=2 4.8 3817.6 - 1.16E+06 - - - -2.5659 - 3.139 0.584 - 203.1 1 2 0 -0.0059 19 0 0 0 1.99E+08 2.05E+08 - - - 4.6945 1 221125_WJC_METTL3_EV_vs_WT_F04.24388.24388.3 9.44E-10 21/72 R.LNEQYEHASIHLWDLLEGK.E "sp|Q14444|CAPR1_HUMAN,tr|G3V153|G3V153_HUMAN" 2 2294.1331 0.88 56433 24388 3 2294.128731 765.7183 Caprin-1 OS=Homo sapiens OX=9606 GN=CAPRIN1 PE=1 SV=2 4.8 3819 - 575462 - - - -1.9249 - 3.958 0.624 - 553.4 1 2 0 -0.0044 19 0 0 0 1.01E+08 1.15E+08 - - - 8.8757 1 221125_WJC_METTL3_EV_vs_WT_F04.24390.24390.3 4.85E-11 22/112 K.AGGPAIPSHLLSTPYPFGLSPSSVVQDSR.F "sp|Q14687|GSE1_HUMAN,tr|C9JLW9|C9JLW9_HUMAN" 2 2936.5032 5.09 56435 24390 3 2936.502099 979.8417 Genetic suppressor element 1 OS=Homo sapiens OX=9606 GN=GSE1 PE=1 SV=3 6.79 3819.3 - 863278 - - - -0.3824 - 4.197 0.671 - 326.4 1 2 0 -0.0011 29 0 0 0 2.40E+07 4.71E+06 - - - 9.3206 0.9229 221125_WJC_METTL3_EV_vs_WT_F04.24391.24391.3 0.0104 Nov-96 K.VNGNPHSTPVSGPPAFLTQGWGSTY.Q sp|Q96I24|FUBP3_HUMAN 1 2570.219 - 56436 24391 3 2570.209771 857.7469 Far upstream element-binding protein 3 OS=Homo sapiens OX=9606 GN=FUBP3 PE=1 SV=2 6.71 3819.4 - 527187 - - - -3.5915 - 2.186 0.409 - 112.8 1 1 0 -0.0092 25 0 0 0 - - - - - 4.8967 0.9984 221125_WJC_METTL3_EV_vs_WT_F04.24392.24392.4 0.00992 May-84 K.NSHLINVLMWELEK[136.11]K[136.11].S "sp|O15372|EIF3H_HUMAN,tr|B3KS98|B3KS98_HUMAN,tr|A0A087WZK9|A0A087WZK9_HUMAN,tr|E5RJT0|E5RJT0_HUMAN" 4 1869.0153 2.23 56437 24392 4 1869.011339 468.2611 Eukaryotic translation initiation factor 3 subunit H OS=Homo sapiens OX=9606 GN=EIF3H PE=1 SV=1 6.76 3819.5 - 67994.1 - - - -2.1407 - 1.139 0.32 - 17.9 1 2 0 -0.004 15 0 0 0 2.86E+06 1.28E+06 - - - 2.0567 1 221125_WJC_METTL3_EV_vs_WT_F04.24394.24394.3 1.13E-08 20/60 K.K[136.11]VSQEILELLNTTTAK[136.11].E "sp|Q86U44|MTA70_HUMAN,tr|H0YFV6|H0YFV6_HUMAN" 2 1803.0324 0.01 56438 24394 3 1803.028648 602.0181 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 6.14 3819.7 - 2.95E+06 - - - -2.0976 - 4.071 0.666 - 806.5 1 2 0 -0.0038 16 0 0 0 1.72E+06 2.40E+08 - - - 9.5664 1 221125_WJC_METTL3_EV_vs_WT_F04.24396.24396.4 1.62E-10 22/108 R.LNEQYEHASIHLWDLLEGK.E "sp|Q14444|CAPR1_HUMAN,tr|G3V153|G3V153_HUMAN" 2 2294.1331 0.97 56439 24396 4 2294.129224 574.5406 Caprin-1 OS=Homo sapiens OX=9606 GN=CAPRIN1 PE=1 SV=2 4.8 3820 - 1.36E+07 - - - -1.71 - 3.975 0.592 - 330.8 1 2 0 -0.0039 19 0 0 0 1.99E+08 2.05E+08 - - - 4.8445 1 221125_WJC_METTL3_EV_vs_WT_F04.24399.24399.3 1.08E-11 18/92 K.QTQIFTTYSDNQPGVLIQVYEGER.A "sp|P0DMV8|HS71A_HUMAN,sp|P34931|HS71L_HUMAN,sp|P0DMV9|HS71B_HUMAN,tr|Q53FA3|Q53FA3_HUMAN,tr|V9GZ37|V9GZ37_HUMAN,tr|A0A0G2JIW1|A0A0G2JIW1_HUMAN" 6 2785.3559 0.18 56442 24399 3 2785.348595 929.4592 Heat shock 70 kDa protein 1A OS=Homo sapiens OX=9606 GN=HSPA1A PE=1 SV=1 4.14 3820.3 - 2.50E+06 - - - -2.6187 - 3.364 0.634 - 306.7 1 2 0 -0.0073 24 0 0 0 2.31E+08 1.28E+09 - - - 8.4241 1 221125_WJC_METTL3_EV_vs_WT_F04.24400.24400.2 1.89E-16 21/46 K.QTQIFTTYSDNQPGVLIQVYEGER[166.11].A "sp|P0DMV8|HS71A_HUMAN,sp|P34931|HS71L_HUMAN,sp|P0DMV9|HS71B_HUMAN,tr|Q53FA3|Q53FA3_HUMAN,tr|V9GZ37|V9GZ37_HUMAN,tr|A0A0G2JIW1|A0A0G2JIW1_HUMAN" 6 2795.3642 0.14 56443 24400 2 2795.354261 1398.6894 Heat shock 70 kDa protein 1A OS=Homo sapiens OX=9606 GN=HSPA1A PE=1 SV=1 4.14 3820.4 - 1.39E+06 - - - -3.5409 - 4.218 0.741 - 790 1 2 0 -0.0099 24 0 0 0 7.77E+06 5.61E+07 - - - 8.0497 0.9993 221125_WJC_METTL3_EV_vs_WT_F04.24402.24402.3 1.59E-05 Nov-52 K.C[160.03]ITDTLQELVNQSK.A "sp|O75694|NU155_HUMAN,tr|E9PF10|E9PF10_HUMAN" 2 1647.8138 1.36 56445 24402 3 1647.808649 550.2785 Nuclear pore complex protein Nup155 OS=Homo sapiens OX=9606 GN=NUP155 PE=1 SV=1 4.37 3820.7 - 666584 - - - -3.1175 - 1.773 0.413 - 110.2 1 2 0 -0.0051 14 0 0 0 3.17E+06 2.34E+06 - - - 4.665 0.9642 221125_WJC_METTL3_EV_vs_WT_F04.24403.24403.3 0.191 May-56 K.NSHLINVLMWELEK[136.11]K[136.11].S "sp|O15372|EIF3H_HUMAN,tr|B3KS98|B3KS98_HUMAN,tr|A0A087WZK9|A0A087WZK9_HUMAN,tr|E5RJT0|E5RJT0_HUMAN" 4 1869.0153 0.1 56446 24403 3 1869.015922 624.0124 Eukaryotic translation initiation factor 3 subunit H OS=Homo sapiens OX=9606 GN=EIF3H PE=1 SV=1 6.76 3820.8 - 422872 - - - 0.3114 - 1.429 0.174 - 18.3 6 2 0 0.0006 15 0 0 0 3.00E+05 2.89E+06 - - - 1.0511 0.9999 221125_WJC_METTL3_EV_vs_WT_F04.24404.24404.4 5.57E-05 Jun-84 K.NSHLINVLMWELEKK.S "sp|O15372|EIF3H_HUMAN,tr|B3KS98|B3KS98_HUMAN,tr|A0A087WZK9|A0A087WZK9_HUMAN,tr|E5RJT0|E5RJT0_HUMAN" 4 1852.9869 2.23 56447 24404 4 1852.983963 464.254 Eukaryotic translation initiation factor 3 subunit H OS=Homo sapiens OX=9606 GN=EIF3H PE=1 SV=1 6.76 3820.9 - 408557 - - - -1.6066 - 1.606 0.434 - 21.3 1 2 0 -0.003 15 0 0 0 2.86E+06 1.28E+06 - - - 3.1722 0.9997 221125_WJC_METTL3_EV_vs_WT_F04.24409.24409.4 3.13E-07 19/192 R.AVGNIVTGTDEQTQVVLNC[160.03]DALSHFPALLTHPK[136.11].E "sp|O00629|IMA3_HUMAN,tr|A0A7I2YQ95|A0A7I2YQ95_HUMAN,tr|H7C4F6|H7C4F6_HUMAN,tr|A0A7I2V340|A0A7I2V340_HUMAN" 4 3552.8126 1.24 56449 24409 4 3552.792035 889.2104 Importin subunit alpha-3 OS=Homo sapiens OX=9606 GN=KPNA4 PE=1 SV=1 5.21 3821.6 - 1.98E+06 - - - -5.7934 - 3.873 0.594 - 200.4 1 2 0 -0.0206 33 0 0 0 9.13E+06 7.39E+06 - - - 4.7967 1 221125_WJC_METTL3_EV_vs_WT_F04.24411.24411.2 5.12E-09 15/36 R.LNEQYEHASIHLWDLLEGK[136.11].E "sp|Q14444|CAPR1_HUMAN,tr|G3V153|G3V153_HUMAN" 2 2302.1473 0.81 56451 24411 2 2302.142903 1152.0809 Caprin-1 OS=Homo sapiens OX=9606 GN=CAPRIN1 PE=1 SV=2 4.8 3821.8 - 1.29E+06 - - - -1.9304 - 3.366 0.668 - 443.1 1 2 0 -0.0044 19 0 0 0 3.66E+06 4.51E+06 - - - 6.9575 1 221125_WJC_METTL3_EV_vs_WT_F04.24412.24412.2 5.71E-14 17/36 R.LNEQYEHASIHLWDLLEGK.E "sp|Q14444|CAPR1_HUMAN,tr|G3V153|G3V153_HUMAN" 2 2294.1331 0.81 56452 24412 2 2294.123178 1148.0738 Caprin-1 OS=Homo sapiens OX=9606 GN=CAPRIN1 PE=1 SV=2 4.8 3822 - 1.28E+06 - - - -4.3454 - 4.015 0.727 - 876.4 1 2 0 -0.01 19 0 0 0 3.66E+06 4.51E+06 - - - 7.825 0.9831 221125_WJC_METTL3_EV_vs_WT_F04.24418.24418.3 0.000337 Nov-92 K.QTQTFTTYSDNQPGVFIQVYEGER[166.11].A sp|P17066|HSP76_HUMAN 1 2817.3121 -1 56456 24418 3 2817.334795 940.1113 Heat shock 70 kDa protein 6 OS=Homo sapiens OX=9606 GN=HSPA6 PE=1 SV=2 4.14 3822.8 - 1.50E+06 - - - 8.0474 - 2.031 0.397 - 100.1 1 2 0 0.0227 24 0 0 0 0.00E+00 0.00E+00 - - - 4.6055 0.9999 221125_WJC_METTL3_EV_vs_WT_F04.24419.24419.3 9.40E-10 19/92 K.C[160.03]ELSSSVQTDINLPYLTMDSSGPK[136.11].H "sp|P38646|GRP75_HUMAN,tr|H0Y8K0|H0Y8K0_HUMAN,tr|A0A7I2V2G2|A0A7I2V2G2_HUMAN,tr|A0A7I2V3F7|A0A7I2V3F7_HUMAN,tr|A0A7I2YQB2|A0A7I2YQB2_HUMAN,tr|D6RCD7|D6RCD7_HUMAN" 6 2649.2393 0.33 56457 24419 3 2649.228575 884.0871 "Stress-70 protein, mitochondrial OS=Homo sapiens OX=9606 GN=HSPA9 PE=1 SV=2" 4.03 3822.9 - 1.07E+06 - - - -4.0612 - 3.617 0.577 - 175.4 1 2 0 -0.0108 24 0 0 0 8.88E+06 2.71E+07 - - - 7.956 1 221125_WJC_METTL3_EV_vs_WT_F04.24423.24423.2 9.76E-12 Nov-46 K.C[160.03]ELSSSVQTDINLPYLTMDSSGPK[136.11].H "sp|P38646|GRP75_HUMAN,tr|H0Y8K0|H0Y8K0_HUMAN,tr|A0A7I2V2G2|A0A7I2V2G2_HUMAN,tr|A0A7I2V3F7|A0A7I2V3F7_HUMAN,tr|A0A7I2YQB2|A0A7I2YQB2_HUMAN,tr|D6RCD7|D6RCD7_HUMAN" 6 2649.2393 0.08 56461 24423 2 2649.237759 1325.6269 "Stress-70 protein, mitochondrial OS=Homo sapiens OX=9606 GN=HSPA9 PE=1 SV=2" 4.03 3823.4 - 0 - - - -0.5945 - 2.969 0.757 - 138.3 1 2 0 -0.0016 24 0 0 0 1.59E+05 1.94E+06 - - - 7.3072 1 221125_WJC_METTL3_EV_vs_WT_F04.24428.24428.4 7.88E-09 17/138 K.QTQIFTTYSDNQPGVLIQVYEGER[166.11].A "sp|P0DMV8|HS71A_HUMAN,sp|P34931|HS71L_HUMAN,sp|P0DMV9|HS71B_HUMAN,tr|Q53FA3|Q53FA3_HUMAN,tr|V9GZ37|V9GZ37_HUMAN,tr|A0A0G2JIW1|A0A0G2JIW1_HUMAN" 6 2795.3642 0.23 56464 24428 4 2795.368088 699.8483 Heat shock 70 kDa protein 1A OS=Homo sapiens OX=9606 GN=HSPA1A PE=1 SV=1 4.14 3824 - 3.34E+06 - - - 1.4055 - 2.878 0.58 - 193.5 1 2 0 0.0039 24 0 0 0 1.10E+07 4.75E+07 - - - 4.6125 0.9999 221125_WJC_METTL3_EV_vs_WT_F04.24429.24429.3 5.73E-05 17/104 K.NFQNIFPPSATLHLSNIPPSVSEEDLK[136.11].V "sp|P26599|PTBP1_HUMAN,tr|A0A0U1RRM4|A0A0U1RRM4_HUMAN,tr|A6NLN1|A6NLN1_HUMAN,tr|A0A0D9SF20|A0A0D9SF20_HUMAN,tr|A0A7I2V621|A0A7I2V621_HUMAN" 5 3001.5277 1.4 56465 24429 3 3001.517837 1001.5165 Polypyrimidine tract-binding protein 1 OS=Homo sapiens OX=9606 GN=PTBP1 PE=1 SV=1 4.65 3824.1 - 1.29E+06 - - - -3.27 - 2.813 0.506 - 132.8 1 2 0 -0.0098 27 0 0 0 1.84E+08 1.32E+08 - - - 6.5581 1 221125_WJC_METTL3_EV_vs_WT_F04.24431.24431.3 9.74E-06 13/56 K.HSQFIGYPITLFVEK[136.11].K "sp|Q58FG0|HS905_HUMAN,sp|P07900|HS90A_HUMAN,tr|G3V2J8|G3V2J8_HUMAN" 3 1785.9545 0.3 56467 24431 3 1785.956817 596.3254 Putative heat shock protein HSP 90-alpha A5 OS=Homo sapiens OX=9606 GN=HSP90AA5P PE=2 SV=1 6.75 3824.4 - 143618 - - - 1.2934 - 2.479 0.517 - 142.2 1 2 0 0.0023 15 0 0 0 1.35E+06 4.44E+06 - - - 6.6723 1 221125_WJC_METTL3_EV_vs_WT_F04.24434.24434.3 2.03E-08 17/60 R.C[160.03]EFEEVQGFLDQVAHK[136.11].L "sp|Q9NX20|RM16_HUMAN,tr|E9PI14|E9PI14_HUMAN" 2 1942.8975 0.66 56468 24434 3 1942.901124 648.6398 "39S ribosomal protein L16, mitochondrial OS=Homo sapiens OX=9606 GN=MRPL16 PE=1 SV=1" 4.4 3824.8 - 1.67E+06 - - - 1.8843 - 3.2 0.532 - 497.6 1 2 0 0.0037 16 0 0 0 2.31E+07 3.48E+07 - - - 7.4547 1 221125_WJC_METTL3_EV_vs_WT_F04.24435.24435.3 2.59E-09 19/104 K.NFQNIFPPSATLHLSNIPPSVSEEDLK.V "sp|P26599|PTBP1_HUMAN,tr|A0A0U1RRM4|A0A0U1RRM4_HUMAN,tr|A6NLN1|A6NLN1_HUMAN,tr|A0A0D9SF20|A0A0D9SF20_HUMAN,tr|A0A7I2V621|A0A7I2V621_HUMAN" 5 2993.5135 1.4 56469 24435 3 2993.51406 998.8451 Polypyrimidine tract-binding protein 1 OS=Homo sapiens OX=9606 GN=PTBP1 PE=1 SV=1 4.65 3824.9 - 1.24E+06 - - - 0.2031 - 3.473 0.637 - 199.6 1 2 0 0.0006 27 0 0 0 1.84E+08 1.32E+08 - - - 8.5061 0.9972 221125_WJC_METTL3_EV_vs_WT_F04.24436.24436.2 0.00029 26-Nov K.GAVHDVKDVLDSVL.- sp|P81605|DCD_HUMAN 1 1465.7777 378.83 56470 24436 2 1465.778143 733.8961 Dermcidin OS=Homo sapiens OX=9606 GN=DCD PE=1 SV=2 4.41 3825 - 1.32E+06 - - - 0.3302 - 2.091 0.397 - 344.4 1 2 1 0.0005 14 0 0 0 4.28E+07 1.13E+05 - - - 3.8242 0.9999 221125_WJC_METTL3_EV_vs_WT_F04.24437.24437.3 3.38E-07 16/52 K.GAVHDVKDVLDSVL.- sp|P81605|DCD_HUMAN 1 1465.7777 302.79 56471 24437 3 1465.77685 489.5998 Dermcidin OS=Homo sapiens OX=9606 GN=DCD PE=1 SV=2 4.41 3825.1 - 856615 - - - -0.5519 - 2.816 0.505 - 264.5 1 2 1 -0.0008 14 0 0 0 3.14E+07 1.04E+05 - - - 6.9214 1 221125_WJC_METTL3_EV_vs_WT_F04.24438.24438.3 3.29E-11 21/100 R.NVLLDPQLVPGGGASEMAVAHALTEK[136.11].S "sp|P49368|TCPG_HUMAN,tr|B4DUR8|B4DUR8_HUMAN" 2 2624.3723 0.07 56472 24438 3 2624.375698 875.7981 T-complex protein 1 subunit gamma OS=Homo sapiens OX=9606 GN=CCT3 PE=1 SV=4 4.65 3825.3 - 852783 - - - 1.2803 - 4.031 0.658 - 319.1 1 2 0 0.0034 26 0 0 0 6.40E+05 8.83E+06 - - - 9.0822 1 221125_WJC_METTL3_EV_vs_WT_F04.24439.24439.4 4.22E-09 29/102 R.DGFIDK[136.11]EDLHDMLASLGK[136.11].N "sp|O14950|ML12B_HUMAN,sp|P19105|ML12A_HUMAN,sp|P24844|MYL9_HUMAN,tr|J3KTJ1|J3KTJ1_HUMAN,tr|J3QRS3|J3QRS3_HUMAN" 5 2018.9954 1.31 56473 24439 4 2018.994745 505.7561 Myosin regulatory light chain 12B OS=Homo sapiens OX=9606 GN=MYL12B PE=1 SV=2 4.35 3825.4 - 771831 - - - -0.3205 - 4.039 0.645 - 715 1 2 1 -0.0006 18 0 0 0 3.97E+07 3.03E+07 - - - 5.3181 1 221125_WJC_METTL3_EV_vs_WT_F04.24442.24442.3 2.43E-12 20/60 R.C[160.03]EFEEVQGFLDQVAHK.L "sp|Q9NX20|RM16_HUMAN,tr|E9PI14|E9PI14_HUMAN" 2 1934.8833 0.61 56474 24442 3 1934.883684 645.9684 "39S ribosomal protein L16, mitochondrial OS=Homo sapiens OX=9606 GN=MRPL16 PE=1 SV=1" 4.4 3825.8 - 2.14E+06 - - - 0.2176 - 3.305 0.684 - 609.2 1 2 0 0.0004 16 0 0 0 2.31E+07 3.78E+07 - - - 9.2331 1 221125_WJC_METTL3_EV_vs_WT_F04.24443.24443.4 1.20E-14 29/102 R.DGFIDKEDLHDMLASLGK.N "sp|O14950|ML12B_HUMAN,sp|P19105|ML12A_HUMAN,sp|P24844|MYL9_HUMAN,tr|J3KTJ1|J3KTJ1_HUMAN,tr|J3QRS3|J3QRS3_HUMAN" 5 2002.967 1.31 56475 24443 4 2002.965467 501.749 Myosin regulatory light chain 12B OS=Homo sapiens OX=9606 GN=MYL12B PE=1 SV=2 4.35 3825.9 - 1.37E+06 - - - -0.7614 - 4.592 0.641 - 794 1 2 1 -0.0015 18 0 0 0 3.97E+07 3.03E+07 - - - 5.327 1 221125_WJC_METTL3_EV_vs_WT_F04.24444.24444.3 0.00089 28/68 R.DGFIDKEDLHDMLASLGK.N "sp|O14950|ML12B_HUMAN,sp|P19105|ML12A_HUMAN,sp|P24844|MYL9_HUMAN,tr|J3KTJ1|J3KTJ1_HUMAN,tr|J3QRS3|J3QRS3_HUMAN" 5 2002.967 1.3 56476 24444 3 2002.973932 668.6629 Myosin regulatory light chain 12B OS=Homo sapiens OX=9606 GN=MYL12B PE=1 SV=2 4.35 3826 - 1.49E+06 - - - 3.4649 - 4.93 0.598 - 1422.4 1 2 1 0.0069 18 0 0 0 4.39E+07 3.39E+07 - - - 9.1777 0.9525 221125_WJC_METTL3_EV_vs_WT_F04.24449.24449.3 0.0032 Jul-64 R.R[166.11]AEQDSTTVAAFASSLV.S "sp|Q86U44|MTA70_HUMAN,tr|F5H6D8|F5H6D8_HUMAN,tr|H0YFV6|H0YFV6_HUMAN,tr|B4DTN4|B4DTN4_HUMAN" 4 1761.8773 0.02 56481 24449 3 1761.877144 588.2997 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 4.37 3826.6 - 464079 - - - -0.0675 - 1.884 0.334 - 48.6 1 1 0 -0.0001 17 0 0 0 1.39E+05 6.80E+06 - - - 3.8639 1 221125_WJC_METTL3_EV_vs_WT_F04.24454.24454.3 3.66E-06 18/88 K.K[136.11]PAFNLSAFGTLSPSLGNSSILK[136.11].T sp|P49790|NU153_HUMAN 1 2364.3024 1.5 56484 24454 3 2364.304632 789.1081 Nuclear pore complex protein Nup153 OS=Homo sapiens OX=9606 GN=NUP153 PE=1 SV=2 10 3827.3 - 476426 - - - 0.9453 - 3.366 0.477 - 272.7 1 2 0 0.0022 23 0 0 0 6.86E+06 4.58E+06 - - - 6.7048 1 221125_WJC_METTL3_EV_vs_WT_F04.24455.24455.3 1.37E-10 22/68 R.DYFEEYGKIDTIEIITDR.Q "sp|P22626|ROA2_HUMAN,tr|A0A7I2YQN4|A0A7I2YQN4_HUMAN,tr|A0A7I2V4N0|A0A7I2V4N0_HUMAN,tr|A0A024RA28|A0A024RA28_HUMAN,tr|A0A7I2V4N1|A0A7I2V4N1_HUMAN,tr|A0A7I2V4I6|A0A7I2V4I6_HUMAN,tr|A0A087WUI2|A0A087WUI2_HUMAN,tr|A0A7I2V4S4|A0A7I2V4S4_HUMAN,tr|A0A7I2V323|A0A7I2V323_HUMAN,tr|A0A7I2V3P1|A0A7I2V3P1_HUMAN,tr|A0A7I2V3P7|A0A7I2V3P7_HUMAN" 11 2219.0634 2.11 56485 24455 3 2219.062422 740.6951 Heterogeneous nuclear ribonucleoproteins A2\B1 OS=Homo sapiens OX=9606 GN=HNRNPA2B1 PE=1 SV=2 4.02 3827.4 - 1.15E+06 - - - -0.4385 - 3.359 0.648 - 593.3 1 2 1 -0.001 18 0 0 0 1.07E+07 5.06E+06 - - - 8.7814 1 221125_WJC_METTL3_EV_vs_WT_F04.24458.24458.3 6.09E-09 21/92 R.VTGQHQGYGFVEFLSEEDADYAIK[136.11].L "sp|Q15427|SF3B4_HUMAN,tr|Q5SZ64|Q5SZ64_HUMAN" 2 2710.2642 0.71 56488 24458 3 2710.267125 904.4287 Splicing factor 3B subunit 4 OS=Homo sapiens OX=9606 GN=SF3B4 PE=1 SV=1 4.17 3827.8 - 503619 - - - 1.0693 - 4.536 0.643 - 552.5 1 2 0 0.0029 24 0 0 0 1.47E+07 2.08E+07 - - - 9.2199 0.9995 221125_WJC_METTL3_EV_vs_WT_F04.24459.24459.3 1.31E-09 14/64 K.SELK[136.11]DFFQSYGNVVELR[166.11].L "sp|Q13283|G3BP1_HUMAN,tr|A0A7I2V5M7|A0A7I2V5M7_HUMAN,tr|A0A7I2YQN9|A0A7I2YQN9_HUMAN,tr|A0A7I2YQH0|A0A7I2YQH0_HUMAN" 4 2048.0334 0.63 56489 24459 3 2048.024641 683.6851 Ras GTPase-activating protein-binding protein 1 OS=Homo sapiens OX=9606 GN=G3BP1 PE=1 SV=1 4.68 3827.9 - 366549 - - - -4.2651 - 3.162 0.586 - 299.6 1 2 1 -0.0087 17 0 0 0 2.29E+06 3.66E+06 - - - 7.9792 0.998 221125_WJC_METTL3_EV_vs_WT_F04.24462.24462.3 5.42E-14 25/120 K.ELEQVC[160.03]NPIISGLYQGAGGPGPGGFGAQGPK[136.11].G "sp|P0DMV8|HS71A_HUMAN,sp|P0DMV9|HS71B_HUMAN,tr|V9GZ37|V9GZ37_HUMAN,tr|A0A0G2JIW1|A0A0G2JIW1_HUMAN" 4 3062.5011 0.13 56490 24462 3 3063.492563 1021.841 Heat shock 70 kDa protein 1A OS=Homo sapiens OX=9606 GN=HSPA1A PE=1 SV=1 4.53 3828.3 - 1.40E+06 - - - 323.7364 - 4.333 0.608 - 599.9 1 2 0 0.9914 31 0 0 0 2.62E+08 2.06E+09 - - - 8.4173 0.9998 221125_WJC_METTL3_EV_vs_WT_F04.24463.24463.3 1.60E-08 17/64 K.SELKDFFQSYGNVVELR.L "sp|Q13283|G3BP1_HUMAN,tr|A0A7I2V5M7|A0A7I2V5M7_HUMAN,tr|A0A7I2YQN9|A0A7I2YQN9_HUMAN,tr|A0A7I2YQH0|A0A7I2YQH0_HUMAN" 4 2030.0109 0.63 56491 24463 3 2030.016573 677.6776 Ras GTPase-activating protein-binding protein 1 OS=Homo sapiens OX=9606 GN=G3BP1 PE=1 SV=1 4.68 3828.4 - 609346 - - - 2.7916 - 3.094 0.603 - 414.3 1 2 1 0.0057 17 0 0 0 2.29E+06 3.66E+06 - - - 8.1147 1 221125_WJC_METTL3_EV_vs_WT_F04.24464.24464.3 2.68E-13 25/68 R.DYFEEYGK[136.11]IDTIEIITDR[166.11].Q "sp|P22626|ROA2_HUMAN,tr|A0A7I2YQN4|A0A7I2YQN4_HUMAN,tr|A0A7I2V4N0|A0A7I2V4N0_HUMAN,tr|A0A024RA28|A0A024RA28_HUMAN,tr|A0A7I2V4N1|A0A7I2V4N1_HUMAN,tr|A0A7I2V4I6|A0A7I2V4I6_HUMAN,tr|A0A087WUI2|A0A087WUI2_HUMAN,tr|A0A7I2V4S4|A0A7I2V4S4_HUMAN,tr|A0A7I2V323|A0A7I2V323_HUMAN,tr|A0A7I2V3P1|A0A7I2V3P1_HUMAN,tr|A0A7I2V3P7|A0A7I2V3P7_HUMAN" 11 2237.0859 2.09 56492 24464 3 2237.083693 746.7026 Heterogeneous nuclear ribonucleoproteins A2\B1 OS=Homo sapiens OX=9606 GN=HNRNPA2B1 PE=1 SV=2 4.02 3828.6 - 1.11E+06 - - - -0.9709 - 4.044 0.713 - 716.1 1 2 1 -0.0022 18 0 0 0 1.07E+07 5.13E+06 - - - 9.9679 1 221125_WJC_METTL3_EV_vs_WT_F04.24465.24465.2 5.43E-15 18/46 K.QTQIFTTYSDNQPGVLIQVYEGER.A "sp|P0DMV8|HS71A_HUMAN,sp|P34931|HS71L_HUMAN,sp|P0DMV9|HS71B_HUMAN,tr|Q53FA3|Q53FA3_HUMAN,tr|V9GZ37|V9GZ37_HUMAN,tr|A0A0G2JIW1|A0A0G2JIW1_HUMAN" 6 2785.3559 0.14 56493 24465 2 2785.357675 1393.6852 Heat shock 70 kDa protein 1A OS=Homo sapiens OX=9606 GN=HSPA1A PE=1 SV=1 4.14 3828.7 - 851320 - - - 0.6412 - 3.834 0.731 - 618.2 1 2 0 0.0018 24 0 0 0 7.77E+06 5.58E+07 - - - 7.7437 1 221125_WJC_METTL3_EV_vs_WT_F04.24466.24466.3 7.10E-05 20/68 K.DSDPVMAGIGEEIAHFQK[136.11].E "sp|P35658|NU214_HUMAN,tr|A0A0A0MSW3|A0A0A0MSW3_HUMAN,tr|A0A494BZU9|A0A494BZU9_HUMAN,tr|A0A494C1F2|A0A494C1F2_HUMAN" 4 1950.9237 1.72 56494 24466 3 1950.925714 651.3152 Nuclear pore complex protein Nup214 OS=Homo sapiens OX=9606 GN=NUP214 PE=1 SV=2 4.31 3828.8 - 605777 - - - 1.0436 - 3.792 0.587 - 473.6 1 2 0 0.002 18 0 0 0 8.16E+07 4.74E+07 - - - 8.4029 1 221125_WJC_METTL3_EV_vs_WT_F04.24471.24471.3 2.04E-08 14/56 K.QYHQEIEEFVSNLVK.R sp|Q6NZY4|ZCHC8_HUMAN 1 1861.921 1.46 56499 24471 3 1861.920488 621.6476 Zinc finger CCHC domain-containing protein 8 OS=Homo sapiens OX=9606 GN=ZCCHC8 PE=1 SV=2 4.75 3829.5 - 315971 - - - -0.29 - 3.029 0.535 - 319.7 1 2 0 -0.0005 15 0 0 0 7.98E+06 5.45E+06 - - - 7.3964 0.9998 221125_WJC_METTL3_EV_vs_WT_F04.24474.24474.3 6.37E-07 17/68 K.EKVGEVTYVELLMDAEGK.S "sp|P52272|HNRPM_HUMAN,tr|M0R019|M0R019_HUMAN,tr|M0R0N3|M0R0N3_HUMAN,tr|A0A087X0X3|A0A087X0X3_HUMAN,tr|M0R2T0|M0R2T0_HUMAN" 5 2009.0027 3.89 56500 24474 3 2009.004112 670.6748 Heterogeneous nuclear ribonucleoprotein M OS=Homo sapiens OX=9606 GN=HNRNPM PE=1 SV=3 4.25 3829.9 - 1.13E+06 - - - 0.6984 - 3.181 0.425 - 366.5 1 2 1 0.0014 18 0 0 0 1.30E+07 3.35E+06 - - - 6.1595 1 221125_WJC_METTL3_EV_vs_WT_F04.24475.24475.3 9.79E-13 25/88 R.YQAVLANLLLEEDNKFC[160.03]ADC[160.03]QSK.G sp|Q8WU79|SMAP2_HUMAN 1 2728.2837 2.09 56501 24475 3 2728.278563 910.4352 Stromal membrane-associated protein 2 OS=Homo sapiens OX=9606 GN=SMAP2 PE=1 SV=1 4.32 3830 - 858534 - - - -1.8656 - 4.823 0.73 - 637.5 1 2 1 -0.0051 23 0 0 0 2.82E+07 1.35E+07 - - - 10.3685 1 221125_WJC_METTL3_EV_vs_WT_F04.24482.24482.3 4.86E-11 14/64 K.VIHDNFGIVEGLMTTVH.A "sp|P04406|G3P_HUMAN,tr|E7EUT5|E7EUT5_HUMAN" 2 1880.9455 - 56508 24482 3 1880.945839 627.9891 Glyceraldehyde-3-phosphate dehydrogenase OS=Homo sapiens OX=9606 GN=GAPDH PE=1 SV=3 5.15 3830.9 - 245350 - - - 0.1967 - 3.071 0.663 - 283.2 1 1 0 0.0004 17 0 0 0 - - - - - 8.7662 1 221125_WJC_METTL3_EV_vs_WT_F04.24486.24486.2 5.90E-11 21/36 K.STNGDTFLGGEDFDQALLR[166.11].H "sp|P38646|GRP75_HUMAN,tr|H0Y8K0|H0Y8K0_HUMAN,tr|A0A7I2V2S7|A0A7I2V2S7_HUMAN,tr|A0A7I2V2G2|A0A7I2V2G2_HUMAN,tr|A0A7I2V3F7|A0A7I2V3F7_HUMAN,tr|A0A7I2YQB2|A0A7I2YQB2_HUMAN,tr|D6RCD7|D6RCD7_HUMAN" 7 2064.9628 0.14 56511 24486 2 2064.96212 1033.4887 "Stress-70 protein, mitochondrial OS=Homo sapiens OX=9606 GN=HSPA9 PE=1 SV=2" 3.84 3831.4 - 656406 - - - -0.3211 - 3.91 0.745 - 1041.4 1 2 0 -0.0007 19 0 0 0 9.80E+05 6.94E+06 - - - 7.8957 1 221125_WJC_METTL3_EV_vs_WT_F04.24487.24487.3 2.70E-10 15/72 K.STNGDTFLGGEDFDQALLR.H "sp|P38646|GRP75_HUMAN,tr|H0Y8K0|H0Y8K0_HUMAN,tr|A0A7I2V2S7|A0A7I2V2S7_HUMAN,tr|A0A7I2V2G2|A0A7I2V2G2_HUMAN,tr|A0A7I2V3F7|A0A7I2V3F7_HUMAN,tr|A0A7I2YQB2|A0A7I2YQB2_HUMAN,tr|D6RCD7|D6RCD7_HUMAN" 7 2054.9545 0.4 56512 24487 3 2054.95926 685.9921 "Stress-70 protein, mitochondrial OS=Homo sapiens OX=9606 GN=HSPA9 PE=1 SV=2" 3.84 3831.5 - 543673 - - - 2.31 - 3.069 0.644 - 348.8 1 2 0 0.0047 19 0 0 0 3.64E+06 9.00E+06 - - - 8.4736 0.9996 221125_WJC_METTL3_EV_vs_WT_F04.24488.24488.3 2.45E-07 Dec-68 K.EK[136.11]VGEVTYVELLMDAEGK[136.11].S "sp|P52272|HNRPM_HUMAN,tr|M0R019|M0R019_HUMAN,tr|M0R0N3|M0R0N3_HUMAN,tr|A0A087X0X3|A0A087X0X3_HUMAN,tr|M0R2T0|M0R2T0_HUMAN" 5 2025.0311 3.89 56513 24488 3 2025.029433 676.0176 Heterogeneous nuclear ribonucleoprotein M OS=Homo sapiens OX=9606 GN=HNRNPM PE=1 SV=3 4.25 3831.6 - 513272 - - - -0.8276 - 2.805 0.386 - 189.2 1 2 1 -0.0017 18 0 0 0 1.30E+07 3.35E+06 - - - 5.4114 0.993 221125_WJC_METTL3_EV_vs_WT_F04.24494.24494.3 0.0185 Jul-44 R.LFPPQWIC[160.03]C[160.03]DIR[166.11].Y sp|Q86U44|MTA70_HUMAN 1 1613.7722 0.001 56519 24494 3 1613.772373 538.9313 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 5.82 3832.4 - 148711 - - - 0.101 - 1.261 0.255 - 57 1 2 0 0.0002 12 0 0 0 0.00E+00 1.59E+06 - - - 2.0258 1 221125_WJC_METTL3_EV_vs_WT_F04.24497.24497.3 5.86E-09 21/96 K.APLATGEDDDDEVPDLVENFDEASK.N "sp|P20290|BTF3_HUMAN,tr|A0A7I2V5Y3|A0A7I2V5Y3_HUMAN" 2 2690.1719 0.55 56520 24497 3 2690.165752 897.7312 Transcription factor BTF3 OS=Homo sapiens OX=9606 GN=BTF3 PE=1 SV=1 3.45 3832.8 - 1.69E+06 - - - -2.2839 - 3.414 0.717 - 400.4 1 2 0 -0.0061 25 0 0 0 2.65E+07 4.79E+07 - - - 9.3571 0.8201 221125_WJC_METTL3_EV_vs_WT_F04.24504.24504.3 0.000375 Sep-84 Q.SVGGDSSADR[166.11]LFPPQWIC[160.03]C[160.03]DIR[166.11].Y sp|Q86U44|MTA70_HUMAN 1 2555.18 0.001 56527 24504 3 2555.176378 852.7339 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 4.43 3833.7 - 208015 - - - -1.4246 - 2.173 0.331 - 63 1 1 1 -0.0036 22 0 0 0 0.00E+00 5.24E+06 - - - 4.0693 1 221125_WJC_METTL3_EV_vs_WT_F04.24507.24507.3 7.29E-09 23/92 R.VTGQHQGYGFVEFLSEEDADYAIK.L "sp|Q15427|SF3B4_HUMAN,tr|Q5SZ64|Q5SZ64_HUMAN" 2 2702.25 0.71 56528 24507 3 2702.257152 901.7573 Splicing factor 3B subunit 4 OS=Homo sapiens OX=9606 GN=SF3B4 PE=1 SV=1 4.17 3834.1 - 1.17E+06 - - - 2.6367 - 4.548 0.66 - 693.6 1 2 0 0.0071 24 0 0 0 1.47E+07 2.08E+07 - - - 9.4144 1 221125_WJC_METTL3_EV_vs_WT_F04.24508.24508.3 1.26E-10 25/92 K.ELTTEIDNNIEQISSYKSEITELR.R "sp|P13645|K1C10_HUMAN,tr|A0A1B0GVI3|A0A1B0GVI3_HUMAN" 2 2824.3978 999 56529 24508 3 2824.40429 942.4732 "Keratin, type I cytoskeletal 10 OS=Homo sapiens OX=9606 GN=KRT10 PE=1 SV=6" 4.14 3834.3 - 776809 - - - 2.2929 - 4.718 0.613 - 701.4 1 2 1 0.0065 24 0 0 0 1.29E+07 0.00E+00 - - - 8.9758 1 221125_WJC_METTL3_EV_vs_WT_F04.24517.24517.4 2.26E-16 28/198 R.MGYAEEAPYDAIHVGAAAPVVPQALIDQLKPGGR.L "sp|P22061|PIMT_HUMAN,tr|F6S8N6|F6S8N6_HUMAN,tr|A0A3F2YNX8|A0A3F2YNX8_HUMAN,tr|A0A0A0MRJ6|A0A0A0MRJ6_HUMAN" 4 3503.7871 1.53 56536 24517 4 3503.798765 876.9541 Protein-L-isoaspartate(D-aspartate) O-methyltransferase OS=Homo sapiens OX=9606 GN=PCMT1 PE=1 SV=4 4.75 3835.6 - 1.14E+06 - - - 3.3221 - 4.234 0.726 - 339.1 1 2 0 0.0116 34 0 0 0 1.17E+07 7.68E+06 - - - 5.9722 1 221125_WJC_METTL3_EV_vs_WT_F04.24518.24518.3 2.39E-12 30/132 K.LGLGIDEDEVAAEEPNAAVPDEIPPLEGDEDASR.M sp|P08238|HS90B_HUMAN 1 3531.6377 1.45 56537 24518 3 3531.644202 1178.2198 Heat shock protein HSP 90-beta OS=Homo sapiens OX=9606 GN=HSP90AB1 PE=1 SV=4 3.43 3835.7 - 1.04E+06 - - - 1.8515 - 3.666 0.675 - 496.8 1 2 0 0.0065 34 0 0 0 1.76E+07 1.21E+07 - - - 9.0525 0.9236 221125_WJC_METTL3_EV_vs_WT_F04.24521.24521.3 1.86E-06 10/120 K.TAFGTSTTGFGTNPGGLFGQQNQQTTSLFSK.P "sp|P52948|NUP98_HUMAN,tr|A0A3B3ITD8|A0A3B3ITD8_HUMAN" 2 3179.516 5.58 56540 24521 3 3179.529716 1060.8459 Nuclear pore complex protein Nup98-Nup96 OS=Homo sapiens OX=9606 GN=NUP98 PE=1 SV=4 8.41 3836.1 - 285513 - - - 4.3227 - 2.483 0.432 - 69.5 1 1 0 0.0137 31 0 0 0 2.03E+06 3.63E+05 - - - 5.4449 0.9619 221125_WJC_METTL3_EV_vs_WT_F04.24528.24528.2 0.000912 22-Oct K.K[136.11]VSQEILELLNT.T "sp|Q86U44|MTA70_HUMAN,tr|H0YFV6|H0YFV6_HUMAN" 2 1393.7908 0.001 56545 24528 2 1393.79434 697.9027 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 4.53 3837 - 1.29E+06 - - - 2.5427 - 2.062 0.427 - 331.1 1 1 0 0.0035 12 0 0 0 0.00E+00 3.64E+07 - - - 4.0978 1 221125_WJC_METTL3_EV_vs_WT_F04.24540.24540.3 1.65E-15 19/88 R.YQAVLANLLLEEDNK[136.11]FC[160.03]ADC[160.03]QSK[136.11].G sp|Q8WU79|SMAP2_HUMAN 1 2744.3121 1.96 56555 24540 3 2744.313579 915.778 Stromal membrane-associated protein 2 OS=Homo sapiens OX=9606 GN=SMAP2 PE=1 SV=1 4.32 3838.6 - 769383 - - - 0.5561 - 4.009 0.757 - 272.8 1 2 1 0.0015 23 0 0 0 2.65E+07 1.35E+07 - - - 10.2368 0.9999 221125_WJC_METTL3_EV_vs_WT_F04.24544.24544.4 1.80E-06 11/126 R.TLVAVERPLDDIIAQLPPPIKK.K "sp|Q969X6|UTP4_HUMAN,tr|H3BRM8|H3BRM8_HUMAN,tr|H3BSH7|H3BSH7_HUMAN,tr|A0A0J9YXV4|A0A0J9YXV4_HUMAN,tr|A0A0J9YWM9|A0A0J9YWM9_HUMAN" 5 2425.4308 1 56559 24544 4 2425.434329 607.365 U3 small nucleolar RNA-associated protein 4 homolog OS=Homo sapiens OX=9606 GN=UTP4 PE=1 SV=1 5.79 3839.1 - 344215 - - - 1.4418 - 2.121 0.413 - 49.2 1 2 0 0.0035 22 0 0 0 6.25E+06 6.27E+06 - - - 3.0658 0.9997 221125_WJC_METTL3_EV_vs_WT_F04.24546.24546.3 0.000174 Nov-52 K.AFYPEEISSMVLTK[136.11].M "sp|P0DMV8|HS71A_HUMAN,sp|P34931|HS71L_HUMAN,sp|P0DMV9|HS71B_HUMAN,tr|Q53FA3|Q53FA3_HUMAN,tr|A0A0G2JIW1|A0A0G2JIW1_HUMAN" 5 1621.8153 0.06 56561 24546 3 1621.820088 541.6124 Heat shock 70 kDa protein 1A OS=Homo sapiens OX=9606 GN=HSPA1A PE=1 SV=1 4.53 3839.4 - 175389 - - - 2.9547 - 1.939 0.449 - 148.7 1 2 0 0.0048 14 0 0 0 3.19E+05 5.33E+06 - - - 5.3043 0.9987 221125_WJC_METTL3_EV_vs_WT_F04.24548.24548.3 0.000131 Oct-56 K.VSQEILELLNTTTAK[136.11].E "sp|Q86U44|MTA70_HUMAN,tr|H0YFV6|H0YFV6_HUMAN" 2 1666.9233 0.03 56563 24548 3 1666.916078 556.6484 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 4.53 3839.6 - 114801 - - - -4.3127 - 2.028 0.407 - 160.3 1 2 0 -0.0072 15 0 0 0 7.78E+04 2.87E+06 - - - 4.9206 1 221125_WJC_METTL3_EV_vs_WT_F04.24551.24551.3 9.51E-15 42/120 K.ELEQVC[160.03]NPIISGLYQGAGGPGPGGFGAQGPK.G "sp|P0DMV8|HS71A_HUMAN,sp|P0DMV9|HS71B_HUMAN,tr|V9GZ37|V9GZ37_HUMAN,tr|A0A0G2JIW1|A0A0G2JIW1_HUMAN" 4 3054.4869 0.13 56564 24551 3 3054.495522 1019.1696 Heat shock 70 kDa protein 1A OS=Homo sapiens OX=9606 GN=HSPA1A PE=1 SV=1 4.53 3840 - 1.94E+06 - - - 2.8162 - 6.351 0.716 - 1956.4 1 2 0 0.0086 31 0 0 0 2.62E+08 2.06E+09 - - - 10.7733 0.9999 221125_WJC_METTL3_EV_vs_WT_F04.24552.24552.4 6.83E-08 30/216 R.ELQEALPEAPAPLLPHITATSLLGTREPDTEVITVEK.S "sp|Q9BXK5|B2L13_HUMAN,tr|A0A087WX97|A0A087WX97_HUMAN,tr|A0A087WTL4|A0A087WTL4_HUMAN" 3 3978.1201 2.22 56565 24552 4 3978.12236 995.5373 Bcl-2-like protein 13 OS=Homo sapiens OX=9606 GN=BCL2L13 PE=1 SV=1 4.3 3840.1 - 1.10E+06 - - - 0.5608 - 3.914 0.565 - 325.1 1 2 1 0.0022 37 0 0 0 7.76E+06 3.50E+06 - - - 4.5432 1 221125_WJC_METTL3_EV_vs_WT_F04.24561.24561.4 2.50E-15 34/180 K.ELEQVC[160.03]NPIISGLYQGAGGPGPGGFGAQGPK[136.11].G "sp|P0DMV8|HS71A_HUMAN,sp|P0DMV9|HS71B_HUMAN,tr|V9GZ37|V9GZ37_HUMAN,tr|A0A0G2JIW1|A0A0G2JIW1_HUMAN" 4 3062.5011 0.13 56572 24561 4 3062.504027 766.6326 Heat shock 70 kDa protein 1A OS=Homo sapiens OX=9606 GN=HSPA1A PE=1 SV=1 4.53 3841.3 - 6.09E+06 - - - 0.9492 - 5.64 0.678 - 876.7 1 2 0 0.0029 31 0 0 0 3.48E+07 2.77E+08 - - - 5.6523 1 221125_WJC_METTL3_EV_vs_WT_F04.24565.24565.3 3.03E-12 21/80 K.LSSC[160.03]DSFTSTINELNHC[160.03]LSLR[166.11].T "sp|P07814|SYEP_HUMAN,tr|V9GZ76|V9GZ76_HUMAN,tr|V9GYZ6|V9GYZ6_HUMAN" 3 2463.1398 0.57 56576 24565 3 2463.139686 822.0539 Bifunctional glutamate\proline--tRNA ligase OS=Homo sapiens OX=9606 GN=EPRS1 PE=1 SV=5 5.32 3841.8 - 643067 - - - -0.0378 - 4.419 0.684 - 701.1 1 2 0 -0.0001 21 0 0 0 7.88E+06 1.39E+07 - - - 9.7283 0.9992 221125_WJC_METTL3_EV_vs_WT_F04.24567.24567.4 0.00247 8/126 R.TLVAVER[166.11]PLDDIIAQLPPPIK[136.11]K[136.11].K "sp|Q969X6|UTP4_HUMAN,tr|H3BRM8|H3BRM8_HUMAN,tr|H3BSH7|H3BSH7_HUMAN,tr|A0A0J9YXV4|A0A0J9YXV4_HUMAN,tr|A0A0J9YWM9|A0A0J9YWM9_HUMAN" 5 2451.4675 1 56578 24567 4 2451.481673 613.8742 U3 small nucleolar RNA-associated protein 4 homolog OS=Homo sapiens OX=9606 GN=UTP4 PE=1 SV=1 5.79 3842 - 520981 - - - 5.7806 - 1.42 0.528 - 18.8 1 2 0 0.0142 22 0 0 0 6.25E+06 6.22E+06 - - - 3.9325 0.9999 221125_WJC_METTL3_EV_vs_WT_F04.24568.24568.4 1.19E-10 20/126 R.TIEDAIAVLSVAEEAADRHPER.R sp|Q96CT7|CC124_HUMAN 1 2391.203 0.93 56579 24568 4 2391.205941 598.808 Coiled-coil domain-containing protein 124 OS=Homo sapiens OX=9606 GN=CCDC124 PE=1 SV=1 4.35 3842.2 - 473436 - - - 1.2228 - 3.156 0.608 - 235.3 1 2 1 0.0029 22 0 0 0 3.31E+07 3.54E+07 - - - 4.8933 1 221125_WJC_METTL3_EV_vs_WT_F04.24569.24569.4 2.00E-06 15/138 K.SLK[136.11]R[166.11]PLEATFDLGIPQAVLPPLPK[136.11].R "sp|Q9NR56|MBNL1_HUMAN,tr|Q86VM6|Q86VM6_HUMAN,tr|A0A0A0MQX8|A0A0A0MQX8_HUMAN,tr|C9JP00|C9JP00_HUMAN" 4 2625.5468 1.73 56580 24569 4 2625.547605 657.394 Muscleblind-like protein 1 OS=Homo sapiens OX=9606 GN=MBNL1 PE=1 SV=2 8.31 3842.3 - 336159 - - - 0.3009 - 2.992 0.658 - 112.4 1 2 1 0.0008 24 0 0 0 6.46E+06 3.73E+06 - - - 5.3048 1 221125_WJC_METTL3_EV_vs_WT_F04.24572.24572.3 6.75E-08 16/52 R.LHFFMPGFAPLTSR[166.11].G "sp|P04350|TBB4A_HUMAN,sp|Q9BVA1|TBB2B_HUMAN,sp|A6NNZ2|TBB8B_HUMAN,sp|P07437|TBB5_HUMAN,sp|Q13885|TBB2A_HUMAN,sp|P68371|TBB4B_HUMAN,sp|Q9BUF5|TBB6_HUMAN,sp|Q3ZCM7|TBB8_HUMAN,tr|Q5ST81|Q5ST81_HUMAN,tr|Q5JP53|Q5JP53_HUMAN,tr|K7ESM5|K7ESM5_HUMAN,tr|A0A075B736|A0A075B736_HUMAN,tr|Q5SQY0|Q5SQY0_HUMAN" 13 1629.8365 0.68 56583 24572 3 1629.84115 544.2861 Tubulin beta-4A chain OS=Homo sapiens OX=9606 GN=TUBB4A PE=1 SV=2 9.76 3842.7 - 191042 - - - 2.8383 - 3.192 0.605 - 363.8 1 2 0 0.0046 14 0 0 0 3.30E+06 4.85E+06 - - - 8.3683 0.9999 221125_WJC_METTL3_EV_vs_WT_F04.24575.24575.4 4.64E-11 25/126 R.TIEDAIAVLSVAEEAADR[166.11]HPER[166.11].R sp|Q96CT7|CC124_HUMAN 1 2411.2196 0.93 56584 24575 4 2411.219653 603.8122 Coiled-coil domain-containing protein 124 OS=Homo sapiens OX=9606 GN=CCDC124 PE=1 SV=1 4.35 3843.1 - 2.00E+06 - - - 0.0398 - 4.044 0.582 - 376.6 1 2 1 0.0001 22 0 0 0 3.31E+07 3.54E+07 - - - 4.7489 1 221125_WJC_METTL3_EV_vs_WT_F04.24576.24576.3 8.61E-19 26/80 K.LSSC[160.03]DSFTSTINELNHC[160.03]LSLR.T "sp|P07814|SYEP_HUMAN,tr|V9GZ76|V9GZ76_HUMAN,tr|V9GYZ6|V9GYZ6_HUMAN" 3 2453.1315 0.57 56585 24576 3 2453.129548 818.7178 Bifunctional glutamate\proline--tRNA ligase OS=Homo sapiens OX=9606 GN=EPRS1 PE=1 SV=5 5.32 3843.2 - 1.02E+06 - - - -0.7994 - 5.023 0.711 - 1158.3 1 2 0 -0.002 21 0 0 0 7.88E+06 1.39E+07 - - - 10.336 1 221125_WJC_METTL3_EV_vs_WT_F04.24580.24580.3 2.97E-08 18/64 K.IIHDFPQFYPLGIVQHD.- "sp|P35244|RFA3_HUMAN,tr|B5MC59|B5MC59_HUMAN" 2 2038.0312 - 56589 24580 3 2038.029361 680.351 Replication protein A 14 kDa subunit OS=Homo sapiens OX=9606 GN=RPA3 PE=1 SV=1 5.22 3843.8 - 252762 - - - -0.9259 - 3.429 0.582 - 462 1 2 0 -0.0019 17 0 0 0 - - - - - 8.1413 1 221125_WJC_METTL3_EV_vs_WT_F04.24583.24583.3 8.23E-09 24/68 K.K[136.11]GDEVQC[160.03]EIEELGVIINK[136.11].V "sp|Q6P2I3|FAH2B_HUMAN,sp|Q96GK7|FAH2A_HUMAN" 2 2088.0744 1.03 56590 24583 3 2088.076131 697.0321 Fumarylacetoacetate hydrolase domain-containing protein 2B OS=Homo sapiens OX=9606 GN=FAHD2B PE=1 SV=1 4.25 3844.2 - 1.34E+06 - - - 0.8429 - 4.092 0.686 - 1000.6 1 2 0 0.0018 18 0 0 0 1.61E+07 1.56E+07 - - - 9.6964 1 221125_WJC_METTL3_EV_vs_WT_F04.24584.24584.3 1.35E-15 22/68 K.KGDEVQC[160.03]EIEELGVIINK.V "sp|Q6P2I3|FAH2B_HUMAN,sp|Q96GK7|FAH2A_HUMAN" 2 2072.046 1.08 56591 24584 3 2072.052866 691.6893 Fumarylacetoacetate hydrolase domain-containing protein 2B OS=Homo sapiens OX=9606 GN=FAHD2B PE=1 SV=1 4.25 3844.3 - 1.37E+06 - - - 3.3276 - 4.186 0.697 - 794.7 1 2 0 0.0069 18 0 0 0 1.64E+07 1.53E+07 - - - 9.8741 1 221125_WJC_METTL3_EV_vs_WT_F04.24587.24587.4 2.38E-08 13/180 R.SAAEMYGSVTEHPSPSPLLSSSFDLDYDFQR.D "sp|P07910|HNRPC_HUMAN,tr|G3V575|G3V575_HUMAN,tr|G3V576|G3V576_HUMAN,tr|G3V555|G3V555_HUMAN,tr|G3V2Q1|G3V2Q1_HUMAN" 5 3432.5456 1.45 56594 24587 4 3432.542498 859.1437 Heterogeneous nuclear ribonucleoproteins C1\C2 OS=Homo sapiens OX=9606 GN=HNRNPC PE=1 SV=4 4.1 3844.6 - 907224 - - - -0.9087 - 2.921 0.599 - 107.1 1 2 0 -0.0031 31 0 0 0 6.83E+06 4.71E+06 - - - 4.7646 1 221125_WJC_METTL3_EV_vs_WT_F04.24589.24589.2 8.50E-14 28/60 K.ELEQVC[160.03]NPIISGLYQGAGGPGPGGFGAQGPK[136.11].G "sp|P0DMV8|HS71A_HUMAN,sp|P0DMV9|HS71B_HUMAN,tr|V9GZ37|V9GZ37_HUMAN,tr|A0A0G2JIW1|A0A0G2JIW1_HUMAN" 4 3062.5011 0.04 56596 24589 2 3062.507037 1532.2578 Heat shock 70 kDa protein 1A OS=Homo sapiens OX=9606 GN=HSPA1A PE=1 SV=1 4.53 3844.9 - 698111 - - - 1.9321 - 5.245 0.756 - 1544.7 1 2 0 0.0059 31 0 0 0 1.69E+06 3.90E+07 - - - 8.6974 1 221125_WJC_METTL3_EV_vs_WT_F04.24591.24591.3 7.77E-12 21/120 R.SAAEMYGSVTEHPSPSPLLSSSFDLDYDFQR[166.11].D "sp|P07910|HNRPC_HUMAN,tr|G3V575|G3V575_HUMAN,tr|G3V576|G3V576_HUMAN,tr|G3V555|G3V555_HUMAN,tr|G3V2Q1|G3V2Q1_HUMAN" 5 3442.5539 1.53 56598 24591 3 3442.552803 1148.5252 Heterogeneous nuclear ribonucleoproteins C1\C2 OS=Homo sapiens OX=9606 GN=HNRNPC PE=1 SV=4 4.1 3845.1 - 518977 - - - -0.3149 - 3.896 0.737 - 383.3 1 2 0 -0.0011 31 0 0 0 1.24E+07 8.13E+06 - - - 9.8853 1 221125_WJC_METTL3_EV_vs_WT_F04.24594.24594.4 5.84E-13 30/156 R.LSKEETVLATVQALQTASHLSQQADLR.S sp|P04844|RPN2_HUMAN 1 2936.5567 1.03 56599 24594 4 2936.555958 735.1465 Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit 2 OS=Homo sapiens OX=9606 GN=RPN2 PE=1 SV=3 5.45 3845.6 - 2.38E+06 - - - -0.2574 - 6.529 0.642 - 578 1 2 1 -0.0008 27 0 0 0 4.83E+07 4.68E+07 - - - 5.4008 1 221125_WJC_METTL3_EV_vs_WT_F04.24595.24595.3 1.67E-15 21/120 R.SAAEMYGSVTEHPSPSPLLSSSFDLDYDFQR.D "sp|P07910|HNRPC_HUMAN,tr|G3V575|G3V575_HUMAN,tr|G3V576|G3V576_HUMAN,tr|G3V555|G3V555_HUMAN,tr|G3V2Q1|G3V2Q1_HUMAN" 5 3432.5456 1.56 56600 24595 3 3432.544902 1145.1891 Heterogeneous nuclear ribonucleoproteins C1\C2 OS=Homo sapiens OX=9606 GN=HNRNPC PE=1 SV=4 4.1 3845.7 - 952508 - - - -0.2083 - 4.316 0.737 - 400.6 1 2 0 -0.0007 31 0 0 0 1.26E+07 8.13E+06 - - - 10.1209 1 221125_WJC_METTL3_EV_vs_WT_F04.24599.24599.3 9.07E-14 20/96 L.YQAELSQMQTQISETNVILSMDNNR.S sp|P04264|K2C1_HUMAN 1 2912.3644 40.3 56604 24599 3 2912.369673 971.7954 "Keratin, type II cytoskeletal 1 OS=Homo sapiens OX=9606 GN=KRT1 PE=1 SV=6" 4.14 3846.1 - 436579 - - - 1.803 - 4.489 0.7 - 381.1 1 1 0 0.0053 25 0 0 0 1.38E+07 3.44E+05 - - - 9.7976 1 221125_WJC_METTL3_EV_vs_WT_F04.24602.24602.3 8.83E-19 31/116 K.DPC[160.03]AAPNEGFC[160.03]SAGVQTEAGVADLTWVGER.G sp|Q9BQA1|MEP50_HUMAN 1 3163.3975 3.22 56605 24602 3 3163.393033 1055.4731 Methylosome protein 50 OS=Homo sapiens OX=9606 GN=WDR77 PE=1 SV=1 3.83 3846.5 - 2.31E+06 - - - -1.4162 - 4.903 0.833 - 968.9 1 2 0 -0.0045 30 0 0 0 1.12E+08 3.46E+07 - - - 11.4835 1 221125_WJC_METTL3_EV_vs_WT_F04.24604.24604.3 2.96E-10 19/116 R.GLPPQQPQQPLLNLQGTNSASLLNGSMLQR.A "sp|Q9ULV3|CIZ1_HUMAN,tr|Q5SYW2|Q5SYW2_HUMAN,tr|F5H2X7|F5H2X7_HUMAN,tr|H0Y5D5|H0Y5D5_HUMAN,tr|F6WSM2|F6WSM2_HUMAN,tr|A0A494C0L7|A0A494C0L7_HUMAN,tr|Q9BTG3|Q9BTG3_HUMAN,tr|F6VD24|F6VD24_HUMAN" 8 3199.6772 4.62 56607 24604 3 3199.677664 1067.5663 Cip1-interacting zinc finger protein OS=Homo sapiens OX=9606 GN=CIZ1 PE=1 SV=2 9.75 3846.7 - 679090 - - - 0.1513 - 3.978 0.65 - 300 1 2 0 0.0005 30 0 0 0 2.69E+07 5.83E+06 - - - 8.9634 1 221125_WJC_METTL3_EV_vs_WT_F04.24607.24607.3 1.54E-12 19/104 K.SSLQYSSPAPDGC[160.03]GDQTLGDLLLTPTR[166.11].L sp|P22102|PUR2_HUMAN 1 2858.3632 8.26 56608 24607 3 2858.365613 953.795 Trifunctional purine biosynthetic protein adenosine-3 OS=Homo sapiens OX=9606 GN=GART PE=1 SV=1 3.93 3847.1 - 946601 - - - 0.8536 - 3.488 0.707 - 318.8 1 2 0 0.0024 27 0 0 0 1.22E+08 1.47E+07 - - - 9.2959 0.9949 221125_WJC_METTL3_EV_vs_WT_F04.24610.24610.2 1.38E-05 24-Nov R.FSGSGSGTDFTLK.L "sp|A2NJV5|KV229_HUMAN,sp|A0A087WW87|KV240_HUMAN,sp|P06310|KV230_HUMAN,sp|A0A075B6S2|KVD29_HUMAN,sp|P01614|KVD40_HUMAN,sp|P01615|KVD28_HUMAN,sp|A0A075B6S6|KVD30_HUMAN,sp|A0A075B6P5|KV228_HUMAN,sp|A0A0A0MRZ7|KVD26_HUMAN" 9 1302.6092 39.6 56611 24610 2 1302.617328 652.3119 Immunoglobulin kappa variable 2-29 OS=Homo sapiens OX=9606 GN=IGKV2-29 PE=3 SV=2 5.84 3847.5 - 269173 - - - 6.2429 - 2.292 0.515 - 186.8 1 2 0 0.0081 13 0 0 0 2.35E+07 5.93E+05 - - - 4.971 1 221125_WJC_METTL3_EV_vs_WT_F04.24617.24617.3 5.34E-12 24/92 R.SPASIEVVK[136.11]PMEAASAILSQADAR[166.11].Q sp|Q9BVP2|GNL3_HUMAN 1 2458.2856 0.77 56616 24617 3 2458.276904 820.4358 Guanine nucleotide-binding protein-like 3 OS=Homo sapiens OX=9606 GN=GNL3 PE=1 SV=2 4.68 3848.4 - 543413 - - - -3.5557 - 4.263 0.672 - 782.5 1 2 0 -0.0087 24 0 0 0 2.31E+07 3.00E+07 - - - 9.3974 0.9992 221125_WJC_METTL3_EV_vs_WT_F04.24618.24618.2 7.96E-08 Aug-32 K.KEESEESDDDMGFGLFD.- "sp|P05387|RLA2_HUMAN,sp|P05386|RLA1_HUMAN,tr|H0YDD8|H0YDD8_HUMAN" 3 1948.752 1.78 56617 24618 2 1948.759565 975.3833 60S acidic ribosomal protein P2 OS=Homo sapiens OX=9606 GN=RPLP2 PE=1 SV=1 3.71 3848.6 - 375365 - - - 3.865 - 1.851 0.665 - 95.9 1 2 0 0.0075 17 0 0 0 6.45E+06 3.62E+06 - - - 5.4641 1 221125_WJC_METTL3_EV_vs_WT_F04.24623.24623.3 2.08E-13 20/112 R.DGTLKPGDTIIEPTSGNTGIGLALAAAVR.G "sp|P35520|CBS_HUMAN,tr|C9JMA6|C9JMA6_HUMAN" 2 2807.5029 0.6 56620 24623 3 2807.50067 936.8416 Cystathionine beta-synthase OS=Homo sapiens OX=9606 GN=CBS PE=1 SV=2 4.56 3849.2 - 1.10E+06 - - - -0.79 - 3.746 0.723 - 176.6 1 2 0 -0.0022 29 0 0 0 9.50E+06 1.58E+07 - - - 9.6385 0.9989 221125_WJC_METTL3_EV_vs_WT_F04.24626.24626.4 0.00104 9/108 K.SEDISK[136.11]FDWLDLDPLSK[136.11]PK[136.11].V "sp|O00443|P3C2A_HUMAN,tr|A0A0C4DGF9|A0A0C4DGF9_HUMAN" 2 2256.174 1.89 56623 24626 4 2256.17538 565.0508 Phosphatidylinositol 4-phosphate 3-kinase C2 domain-containing subunit alpha OS=Homo sapiens OX=9606 GN=PIK3C2A PE=1 SV=2 4.36 3849.6 - 273630 - - - 0.605 - 1.687 0.372 - 50 1 2 1 0.0014 19 0 0 0 5.04E+06 2.67E+06 - - - 2.6404 1 221125_WJC_METTL3_EV_vs_WT_F04.24629.24629.3 5.87E-14 20/60 K.K[136.11]VSQEILELLNTTTAK[136.11].E "sp|Q86U44|MTA70_HUMAN,tr|H0YFV6|H0YFV6_HUMAN" 2 1803.0324 0.02 56624 24629 3 1803.030942 602.0181 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 6.14 3850 - 1.83E+06 - - - -0.8253 - 4.183 0.621 - 754.5 1 2 0 -0.0015 16 0 0 0 1.18E+06 7.22E+07 - - - 9.135 1 221125_WJC_METTL3_EV_vs_WT_F04.24630.24630.4 2.63E-11 18/174 K.DPC[160.03]AAPNEGFC[160.03]SAGVQTEAGVADLTWVGER.G sp|Q9BQA1|MEP50_HUMAN 1 3163.3975 5.46 56625 24630 4 3163.396632 791.8567 Methylosome protein 50 OS=Homo sapiens OX=9606 GN=WDR77 PE=1 SV=1 3.83 3850.1 - 604313 - - - -0.2785 - 3.734 0.643 - 232.6 1 2 0 -0.0009 30 0 0 0 7.64E+06 1.40E+06 - - - 5.2256 1 221125_WJC_METTL3_EV_vs_WT_F04.24632.24632.4 1.05E-14 30/180 K.ELEQVC[160.03]NPIISGLYQGAGGPGPGGFGAQGPK.G "sp|P0DMV8|HS71A_HUMAN,sp|P0DMV9|HS71B_HUMAN,tr|V9GZ37|V9GZ37_HUMAN,tr|A0A0G2JIW1|A0A0G2JIW1_HUMAN" 4 3054.4869 0.13 56627 24632 4 3054.488652 764.629 Heat shock 70 kDa protein 1A OS=Homo sapiens OX=9606 GN=HSPA1A PE=1 SV=1 4.53 3850.4 - 1.55E+06 - - - 0.567 - 5.328 0.57 - 677.3 1 2 0 0.0017 31 0 0 0 3.48E+07 2.77E+08 - - - 4.6953 0.984 221125_WJC_METTL3_EV_vs_WT_F04.24635.24635.3 3.90E-06 Nov-92 R.DYTR[166.11]PDLPSGDSQPSLDQTMAAAF.G "sp|P26599|PTBP1_HUMAN,tr|A0A6Q8PEX4|A0A6Q8PEX4_HUMAN,tr|A0A0U1RRM4|A0A0U1RRM4_HUMAN,tr|A6NLN1|A6NLN1_HUMAN,tr|A0A087WU68|A0A087WU68_HUMAN,tr|A0A7I2V4H6|A0A7I2V4H6_HUMAN,tr|A0A7I2V621|A0A7I2V621_HUMAN,tr|A0A087WTS6|A0A087WTS6_HUMAN,tr|K7EK45|K7EK45_HUMAN" 9 2592.1678 3.17 56630 24635 3 2592.15845 865.0632 Polypyrimidine tract-binding protein 1 OS=Homo sapiens OX=9606 GN=PTBP1 PE=1 SV=1 3.77 3850.7 - 834424 - - - -3.5943 - 2.4 0.546 - 71.2 1 1 0 -0.0093 24 0 0 0 5.33E+07 1.68E+07 - - - 6.6581 0.9999 221125_WJC_METTL3_EV_vs_WT_F04.24636.24636.3 0.00666 16/60 K.GFDQTINLILDESHER.V "sp|O95777|LSM8_HUMAN,tr|C9JNV3|C9JNV3_HUMAN,tr|C9JIZ0|C9JIZ0_HUMAN,tr|F2Z2Y6|F2Z2Y6_HUMAN" 4 1885.917 2.69 56631 24636 3 1885.913627 629.6463 U6 snRNA-associated Sm-like protein LSm8 OS=Homo sapiens OX=9606 GN=LSM8 PE=1 SV=3 4.31 3850.9 - 527388 - - - -1.7917 - 2.949 0.41 - 323.6 1 2 0 -0.0034 16 0 0 0 1.03E+07 3.84E+06 - - - 5.8851 1 221125_WJC_METTL3_EV_vs_WT_F04.24644.24644.3 1.23E-12 26/92 R.KLISEVDSDGDGEISFQEFLTAAK.K sp|Q9NZT1|CALL5_HUMAN 1 2598.2701 168.19 56636 24644 3 2598.287896 867.0973 Calmodulin-like protein 5 OS=Homo sapiens OX=9606 GN=CALML5 PE=1 SV=2 4.02 3851.8 - 707013 - - - 6.8515 - 4.785 0.69 - 890.1 1 2 0 0.0178 24 0 0 0 4.95E+07 2.95E+05 - - - 9.8639 1 221125_WJC_METTL3_EV_vs_WT_F04.24645.24645.3 2.28E-09 15/116 R.GLPPQQPQQPLLNLQGTNSASLLNGSMLQR[166.11].A "sp|Q9ULV3|CIZ1_HUMAN,tr|Q5SYW2|Q5SYW2_HUMAN,tr|F5H2X7|F5H2X7_HUMAN,tr|H0Y5D5|H0Y5D5_HUMAN,tr|F6WSM2|F6WSM2_HUMAN,tr|A0A494C0L7|A0A494C0L7_HUMAN,tr|Q9BTG3|Q9BTG3_HUMAN,tr|F6VD24|F6VD24_HUMAN" 8 3209.6854 4.64 56637 24645 3 3209.686418 1070.9024 Cip1-interacting zinc finger protein OS=Homo sapiens OX=9606 GN=CIZ1 PE=1 SV=2 9.75 3852 - 426056 - - - 0.3016 - 3.5 0.586 - 188.9 1 2 0 0.001 30 0 0 0 2.55E+07 5.49E+06 - - - 7.9552 1 221125_WJC_METTL3_EV_vs_WT_F04.24646.24646.3 2.51E-08 15/64 K.GLEHVTVDDLVAEITPK.G "sp|Q9NPA8|ENY2_HUMAN,tr|E5RHX8|E5RHX8_HUMAN" 2 1834.9676 1.7 56638 24646 3 1834.972194 612.6632 Transcription and mRNA export factor ENY2 OS=Homo sapiens OX=9606 GN=ENY2 PE=1 SV=1 4.31 3852.1 - 369373 - - - 2.4796 - 2.794 0.568 - 170.3 1 2 0 0.0046 17 0 0 0 1.01E+07 5.97E+06 - - - 7.4671 1 221125_WJC_METTL3_EV_vs_WT_F04.24650.24650.3 2.46E-06 23/92 R.SPASIEVVKPMEAASAILSQADAR.Q sp|Q9BVP2|GNL3_HUMAN 1 2440.2632 0.77 56639 24650 3 2440.26711 814.4283 Guanine nucleotide-binding protein-like 3 OS=Homo sapiens OX=9606 GN=GNL3 PE=1 SV=2 4.68 3852.7 - 1.27E+06 - - - 1.6125 - 4.085 0.583 - 566.3 1 2 0 0.0039 24 0 0 0 2.31E+07 3.00E+07 - - - 8.3074 1 221125_WJC_METTL3_EV_vs_WT_F04.24652.24652.3 4.23E-07 19/92 K.GHNGWVTQIATTPQFPDMILSASR[166.11].D "sp|P63244|RACK1_HUMAN,tr|D6RFZ9|D6RFZ9_HUMAN,tr|D6RAU2|D6RAU2_HUMAN,tr|D6RDI0|D6RDI0_HUMAN,tr|J3KPE3|J3KPE3_HUMAN,tr|D6RHJ5|D6RHJ5_HUMAN,tr|D6RHH4|D6RHH4_HUMAN,tr|D6RBD0|D6RBD0_HUMAN,tr|D6R909|D6R909_HUMAN,tr|D6RAC2|D6RAC2_HUMAN,tr|D6RGK8|D6RGK8_HUMAN,tr|E9PD14|E9PD14_HUMAN,tr|D6REE5|D6REE5_HUMAN" 13 2636.3045 1.06 56641 24652 3 2636.301517 879.7754 Receptor of activated protein C kinase 1 OS=Homo sapiens OX=9606 GN=RACK1 PE=1 SV=3 6.74 3852.9 - 583801 - - - -1.1224 - 3.86 0.615 - 304.6 1 2 0 -0.003 24 0 0 0 2.21E+07 2.09E+07 - - - 8.5329 1 221125_WJC_METTL3_EV_vs_WT_F04.24656.24656.3 1.54E-13 18/116 K.DPC[160.03]AAPNEGFC[160.03]SAGVQTEAGVADLTWVGER[166.11].G sp|Q9BQA1|MEP50_HUMAN 1 3173.4058 3.22 56643 24656 3 3173.410019 1058.8092 Methylosome protein 50 OS=Homo sapiens OX=9606 GN=WDR77 PE=1 SV=1 3.83 3853.5 - 822274 - - - 1.3348 - 3.625 0.713 - 300.7 1 2 0 0.0042 30 0 0 0 1.12E+08 3.46E+07 - - - 9.451 0.9992 221125_WJC_METTL3_EV_vs_WT_F04.24659.24659.3 4.97E-06 16/84 R.GSNTIASAAADKIPGLLGVFQK.L sp|P55060|XPO2_HUMAN 1 2157.1794 0.77 56646 24659 3 2157.185173 720.0671 Exportin-2 OS=Homo sapiens OX=9606 GN=CSE1L PE=1 SV=3 8.59 3853.9 - 514342 - - - 2.691 - 2.438 0.455 - 178.8 1 2 1 0.0058 22 0 0 0 9.06E+06 1.18E+07 - - - 5.724 1 221125_WJC_METTL3_EV_vs_WT_F04.24667.24667.3 5.10E-05 19/124 R.ILHTLLASGEDALDFTQESEPSYISDVGPPGR.S "sp|Q8N1F7|NUP93_HUMAN,tr|H3BM93|H3BM93_HUMAN,tr|H3BP95|H3BP95_HUMAN,tr|H3BVG0|H3BVG0_HUMAN,tr|H3BMX0|H3BMX0_HUMAN" 5 3413.6627 4.86 56652 24667 3 3413.667214 1138.8948 Nuclear pore complex protein Nup93 OS=Homo sapiens OX=9606 GN=NUP93 PE=1 SV=2 4.01 3854.9 - 981097 - - - 1.3235 - 2.575 0.536 - 202.4 1 2 0 0.0045 32 0 0 0 1.30E+07 2.68E+06 - - - 6.6907 1 221125_WJC_METTL3_EV_vs_WT_F04.24669.24669.4 2.22E-09 25/132 R.GFGFVTYATVEEVDAAMNAR[166.11]PHK[136.11].V "sp|P09651|ROA1_HUMAN,tr|A0A7I2YQX9|A0A7I2YQX9_HUMAN,tr|A0A7I2V3W4|A0A7I2V3W4_HUMAN,tr|F8W646|F8W646_HUMAN,tr|F8VZ49|F8VZ49_HUMAN,tr|A0A7I2V3R8|A0A7I2V3R8_HUMAN,tr|F8W6I7|F8W6I7_HUMAN,tr|F8VYN5|F8VYN5_HUMAN,tr|A0A7I2V2L6|A0A7I2V2L6_HUMAN,tr|A0A7I2V3C7|A0A7I2V3C7_HUMAN,tr|A0A7I2V3W0|A0A7I2V3W0_HUMAN,tr|A0A7I2YQV3|A0A7I2YQV3_HUMAN,tr|A0A2R8Y4L2|A0A2R8Y4L2_HUMAN,tr|A0A7I2V2Z4|A0A7I2V2Z4_HUMAN,tr|A0A7I2V4M0|A0A7I2V4M0_HUMAN" 15 2527.2285 1.36 56654 24669 4 2527.226178 632.8144 Heterogeneous nuclear ribonucleoprotein A1 OS=Homo sapiens OX=9606 GN=HNRNPA1 PE=1 SV=5 5.45 3855.2 - 1.15E+06 - - - -0.9045 - 4.679 0.461 - 391.9 1 2 0 -0.0023 23 0 0 0 9.77E+07 7.17E+07 - - - 3.7378 0.9999 221125_WJC_METTL3_EV_vs_WT_F04.24671.24671.3 3.29E-06 17/84 R.GSNTIASAAADK[136.11]IPGLLGVFQK[136.11].L sp|P55060|XPO2_HUMAN 1 2173.2078 0.77 56656 24671 3 2173.209251 725.4099 Exportin-2 OS=Homo sapiens OX=9606 GN=CSE1L PE=1 SV=3 8.59 3855.4 - 826865 - - - 0.6824 - 3.234 0.531 - 187.2 1 2 1 0.0015 22 0 0 0 9.06E+06 1.18E+07 - - - 7.2424 0.9999 221125_WJC_METTL3_EV_vs_WT_F04.24672.24672.3 7.13E-09 15/84 K.DGVFLYFEDNAGVIVNNK[136.11]GEMK[136.11].G "sp|P62829|RL23_HUMAN,tr|J3KT29|J3KT29_HUMAN,tr|J3KTJ3|J3KTJ3_HUMAN" 3 2474.2123 0.67 56657 24672 3 2474.21565 825.7447 60S ribosomal protein L23 OS=Homo sapiens OX=9606 GN=RPL23 PE=1 SV=1 4.32 3855.6 - 785610 - - - 1.3693 - 3.234 0.595 - 195.7 1 2 1 0.0034 22 0 0 0 3.44E+06 5.15E+06 - - - 7.9554 1 221125_WJC_METTL3_EV_vs_WT_F04.24674.24674.3 1.96E-09 15/112 K.SIDDTSNFDDFPESDILQPVPNTTEPDYK.S sp|Q9Y2H1|ST38L_HUMAN 1 3298.4677 13.98 56659 24674 3 3298.470959 1100.4965 Serine\threonine-protein kinase 38-like OS=Homo sapiens OX=9606 GN=STK38L PE=1 SV=3 3.5 3855.8 - 458047 - - - 0.9747 - 2.689 0.699 - 155.8 1 2 0 0.0032 29 0 0 0 2.51E+07 1.80E+06 - - - 8.608 1 221125_WJC_METTL3_EV_vs_WT_F04.24676.24676.3 1.74E-09 16/104 K.NFQNIFPPSATLHLSNIPPSVSEEDLK.V "sp|P26599|PTBP1_HUMAN,tr|A0A0U1RRM4|A0A0U1RRM4_HUMAN,tr|A6NLN1|A6NLN1_HUMAN,tr|A0A0D9SF20|A0A0D9SF20_HUMAN,tr|A0A7I2V621|A0A7I2V621_HUMAN" 5 2993.5135 1.29 56660 24676 3 2993.518811 998.8451 Polypyrimidine tract-binding protein 1 OS=Homo sapiens OX=9606 GN=PTBP1 PE=1 SV=1 4.65 3856.2 - 1.05E+06 - - - 1.7902 - 3.344 0.581 - 127.5 1 2 0 0.0054 27 0 0 0 3.97E+07 3.08E+07 - - - 7.7933 1 221125_WJC_METTL3_EV_vs_WT_F04.24678.24678.4 1.39E-06 29/132 R.GFGFVTYATVEEVDAAMNARPHK.V "sp|P09651|ROA1_HUMAN,tr|A0A7I2YQX9|A0A7I2YQX9_HUMAN,tr|A0A7I2V3W4|A0A7I2V3W4_HUMAN,tr|F8W646|F8W646_HUMAN,tr|F8VZ49|F8VZ49_HUMAN,tr|A0A7I2V3R8|A0A7I2V3R8_HUMAN,tr|F8W6I7|F8W6I7_HUMAN,tr|F8VYN5|F8VYN5_HUMAN,tr|A0A7I2V2L6|A0A7I2V2L6_HUMAN,tr|A0A7I2V3C7|A0A7I2V3C7_HUMAN,tr|A0A7I2V3W0|A0A7I2V3W0_HUMAN,tr|A0A7I2YQV3|A0A7I2YQV3_HUMAN,tr|A0A2R8Y4L2|A0A2R8Y4L2_HUMAN,tr|A0A7I2V2Z4|A0A7I2V2Z4_HUMAN,tr|A0A7I2V4M0|A0A7I2V4M0_HUMAN" 15 2509.206 1.37 56661 24678 4 2509.210029 628.3088 Heterogeneous nuclear ribonucleoprotein A1 OS=Homo sapiens OX=9606 GN=HNRNPA1 PE=1 SV=5 5.45 3856.4 - 2.91E+06 - - - 1.6081 - 4.819 0.563 - 503.6 1 2 0 0.004 23 0 0 0 9.81E+07 7.17E+07 - - - 4.6347 0.9998 221125_WJC_METTL3_EV_vs_WT_F04.24680.24680.2 0.000148 24-Nov K.TLNDELEIIEGMK[136.11].F "sp|P10809|CH60_HUMAN,tr|A0A7I2V2X6|A0A7I2V2X6_HUMAN,tr|A0A7I2V599|A0A7I2V599_HUMAN,tr|E7EXB4|E7EXB4_HUMAN,tr|A0A7I2YQ71|A0A7I2YQ71_HUMAN,tr|E7ESH4|E7ESH4_HUMAN,tr|A0A7I2V5M1|A0A7I2V5M1_HUMAN,tr|A0A7I2V5K3|A0A7I2V5K3_HUMAN,tr|A0A7I2V369|A0A7I2V369_HUMAN" 9 1511.7633 1.41 56663 24680 2 1511.765736 756.8889 "60 kDa heat shock protein, mitochondrial OS=Homo sapiens OX=9606 GN=HSPD1 PE=1 SV=2" 4 3856.7 - 898264 - - - 1.6372 - 2.299 0.502 - 240.8 1 2 0 0.0025 13 0 0 0 1.40E+07 9.94E+06 - - - 4.8846 0.939 221125_WJC_METTL3_EV_vs_WT_F04.24682.24682.3 0.067 15/76 K.K[136.11]LLHHLSDLALTLPTDAVSI.C "sp|Q86U44|MTA70_HUMAN,tr|B4E349|B4E349_HUMAN,tr|F5H6D8|F5H6D8_HUMAN,tr|H0YFV6|H0YFV6_HUMAN,tr|B4DTN4|B4DTN4_HUMAN" 5 2164.2347 0.001 56665 24682 3 2164.242192 722.4188 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 5.98 3856.9 - 486451 - - - 3.4594 - 2.661 0.372 - 199.3 1 1 0 0.0075 20 0 0 0 0.00E+00 7.66E+07 - - - 5.0597 0.9999 221125_WJC_METTL3_EV_vs_WT_F04.24684.24684.3 2.84E-05 Oct-48 K.TLNDELEIIEGMK.F "sp|P10809|CH60_HUMAN,tr|A0A7I2V2X6|A0A7I2V2X6_HUMAN,tr|A0A7I2V599|A0A7I2V599_HUMAN,tr|E7EXB4|E7EXB4_HUMAN,tr|A0A7I2YQ71|A0A7I2YQ71_HUMAN,tr|E7ESH4|E7ESH4_HUMAN,tr|A0A7I2V5M1|A0A7I2V5M1_HUMAN,tr|A0A7I2V5K3|A0A7I2V5K3_HUMAN,tr|A0A7I2V369|A0A7I2V369_HUMAN" 9 1503.7491 1.89 56667 24684 3 1503.748986 502.257 "60 kDa heat shock protein, mitochondrial OS=Homo sapiens OX=9606 GN=HSPD1 PE=1 SV=2" 4 3857.2 - 371544 - - - -0.0499 - 2.057 0.43 - 210.5 1 2 0 -0.0001 13 0 0 0 2.71E+06 1.44E+06 - - - 5.2896 0.9994 221125_WJC_METTL3_EV_vs_WT_F04.24686.24686.3 7.57E-05 Sep-48 K.TLNDELEIIEGMK[136.11].F "sp|P10809|CH60_HUMAN,tr|A0A7I2V2X6|A0A7I2V2X6_HUMAN,tr|A0A7I2V599|A0A7I2V599_HUMAN,tr|E7EXB4|E7EXB4_HUMAN,tr|A0A7I2YQ71|A0A7I2YQ71_HUMAN,tr|E7ESH4|E7ESH4_HUMAN,tr|A0A7I2V5M1|A0A7I2V5M1_HUMAN,tr|A0A7I2V5K3|A0A7I2V5K3_HUMAN,tr|A0A7I2V369|A0A7I2V369_HUMAN" 9 1511.7633 1.89 56669 24686 3 1511.763228 504.9284 "60 kDa heat shock protein, mitochondrial OS=Homo sapiens OX=9606 GN=HSPD1 PE=1 SV=2" 4 3857.5 - 249892 - - - -0.0218 - 1.802 0.316 - 103.8 1 2 0 0 13 0 0 0 2.71E+06 1.44E+06 - - - 3.6597 1 221125_WJC_METTL3_EV_vs_WT_F04.24692.24692.3 2.02E-09 28/92 K.GHNGWVTQIATTPQFPDMILSASR.D "sp|P63244|RACK1_HUMAN,tr|D6RFZ9|D6RFZ9_HUMAN,tr|D6RAU2|D6RAU2_HUMAN,tr|D6RDI0|D6RDI0_HUMAN,tr|J3KPE3|J3KPE3_HUMAN,tr|D6RHJ5|D6RHJ5_HUMAN,tr|D6RHH4|D6RHH4_HUMAN,tr|D6RBD0|D6RBD0_HUMAN,tr|D6R909|D6R909_HUMAN,tr|D6RAC2|D6RAC2_HUMAN,tr|D6RGK8|D6RGK8_HUMAN,tr|E9PD14|E9PD14_HUMAN,tr|D6REE5|D6REE5_HUMAN" 13 2626.2962 1.05 56673 24692 3 2626.30047 876.4393 Receptor of activated protein C kinase 1 OS=Homo sapiens OX=9606 GN=RACK1 PE=1 SV=3 6.74 3858.2 - 1.32E+06 - - - 1.6236 - 4.166 0.602 - 757.5 1 2 0 0.0043 24 0 0 0 2.21E+07 2.11E+07 - - - 8.5648 1 221125_WJC_METTL3_EV_vs_WT_F04.24694.24694.3 7.33E-09 14/104 K.NFQNIFPPSATLHLSNIPPSVSEEDLK[136.11].V "sp|P26599|PTBP1_HUMAN,tr|A0A0U1RRM4|A0A0U1RRM4_HUMAN,tr|A6NLN1|A6NLN1_HUMAN,tr|A0A0D9SF20|A0A0D9SF20_HUMAN,tr|A0A7I2V621|A0A7I2V621_HUMAN" 5 3001.5277 1.43 56675 24694 3 3001.530225 1001.5165 Polypyrimidine tract-binding protein 1 OS=Homo sapiens OX=9606 GN=PTBP1 PE=1 SV=1 4.65 3858.4 - 716417 - - - 0.8572 - 3.15 0.59 - 102.7 1 2 0 0.0026 27 0 0 0 5.85E+07 4.09E+07 - - - 7.757 1 221125_WJC_METTL3_EV_vs_WT_F04.24696.24696.3 1.93E-16 18/124 R.ILHTLLASGEDALDFTQESEPSYISDVGPPGR[166.11].S "sp|Q8N1F7|NUP93_HUMAN,tr|H3BM93|H3BM93_HUMAN,tr|H3BP95|H3BP95_HUMAN,tr|H3BVG0|H3BVG0_HUMAN,tr|H3BMX0|H3BMX0_HUMAN" 5 3423.671 4.86 56677 24696 3 3423.676654 1142.2309 Nuclear pore complex protein Nup93 OS=Homo sapiens OX=9606 GN=NUP93 PE=1 SV=2 4.01 3858.7 - 320568 - - - 1.6614 - 3.686 0.753 - 211 1 2 0 0.0057 32 0 0 0 1.30E+07 2.68E+06 - - - 9.9349 1 221125_WJC_METTL3_EV_vs_WT_F04.24702.24702.3 6.85E-07 24/88 K.TGIASSILDAISQGSESQHALEK.C sp|Q9HCJ3|RAVR2_HUMAN 1 2341.1761 1.46 56681 24702 3 2341.182139 781.3993 Ribonucleoprotein PTB-binding 2 OS=Homo sapiens OX=9606 GN=RAVER2 PE=1 SV=2 4.65 3859.5 - 1.13E+06 - - - 2.565 - 4.546 0.55 - 496.1 1 2 0 0.006 23 0 0 0 1.40E+08 9.62E+07 - - - 8.2226 0.9879 221125_WJC_METTL3_EV_vs_WT_F04.24704.24704.3 7.40E-08 20/80 -.MR[166.11]YVASYLLAALGGNSSPSAK[136.11].D sp|P05387|RLA2_HUMAN 1 2173.132 1.22 56683 24704 3 2173.112724 725.3846 60S acidic ribosomal protein P2 OS=Homo sapiens OX=9606 GN=RPLP2 PE=1 SV=1 9.7 3859.8 - 574462 - - - -8.8904 - 3.799 0.48 - 465.1 1 2 1 -0.0193 21 0 0 0 8.78E+07 7.19E+07 - - - 7.0861 1 221125_WJC_METTL3_EV_vs_WT_F04.24705.24705.3 2.54E-10 24/152 K.SGLVGGQLSGGLGLPPGKPPSSSPLTGASPPSFLQGLC[160.03]R.D sp|Q9H7S9|ZN703_HUMAN 1 3729.9512 2.36 56684 24705 3 3729.952893 1244.3244 Zinc finger protein 703 OS=Homo sapiens OX=9606 GN=ZNF703 PE=1 SV=1 9.5 3859.9 - 441131 - - - 0.4459 - 3.539 0.666 - 201.3 1 2 0 0.0017 39 0 0 0 3.72E+07 1.57E+07 - - - 8.8724 0.9959 221125_WJC_METTL3_EV_vs_WT_F04.24707.24707.2 0.119 22-Jul R.AQFEGIVTDLIR[166.11].R "sp|P38646|GRP75_HUMAN,tr|H0Y8K0|H0Y8K0_HUMAN,tr|A0A7I2V2S7|A0A7I2V2S7_HUMAN,tr|A0A7I2V2G2|A0A7I2V2G2_HUMAN,tr|A0A7I2V3F7|A0A7I2V3F7_HUMAN,tr|A0A7I2YQB2|A0A7I2YQB2_HUMAN,tr|D6RCD7|D6RCD7_HUMAN" 7 1370.7433 0.42 56686 24707 2 1370.742565 686.3789 "Stress-70 protein, mitochondrial OS=Homo sapiens OX=9606 GN=HSPA9 PE=1 SV=2" 4.37 3860.1 - 318758 - - - -0.5617 - 1.23 0.228 - 66.6 1 2 0 -0.0008 12 0 0 0 1.34E+06 3.17E+06 - - - 1.2695 1 221125_WJC_METTL3_EV_vs_WT_F04.24712.24712.4 5.92E-10 32/228 K.SGLVGGQLSGGLGLPPGKPPSSSPLTGASPPSFLQGLC[160.03]R.D sp|Q9H7S9|ZN703_HUMAN 1 3729.9512 1.14 56689 24712 4 3729.950318 933.4951 Zinc finger protein 703 OS=Homo sapiens OX=9606 GN=ZNF703 PE=1 SV=1 9.5 3860.8 - 1.84E+06 - - - -0.2445 - 4.898 0.587 - 351.8 1 2 0 -0.0009 39 0 0 0 7.09E+07 6.23E+07 - - - 4.7959 0.9579 221125_WJC_METTL3_EV_vs_WT_F04.24713.24713.3 0.00027 8/140 R.LASLMNLGMSSSLNQQGAHSALSSASTSSHNLQSIF.N "sp|P43243|MATR3_HUMAN,tr|D6RBS2|D6RBS2_HUMAN,tr|A8MXP9|A8MXP9_HUMAN,tr|D6R991|D6R991_HUMAN,tr|D6REK4|D6REK4_HUMAN,tr|A0A0R4J2E8|A0A0R4J2E8_HUMAN,tr|D6RCM3|D6RCM3_HUMAN,tr|D6R8Z5|D6R8Z5_HUMAN,tr|D6REM6|D6REM6_HUMAN" 9 3675.7621 - 56690 24713 3 3675.756901 1226.2613 Matrin-3 OS=Homo sapiens OX=9606 GN=MATR3 PE=1 SV=2 6.92 3861 - 507914 - - - -1.4168 - 2.297 0.33 - 25.9 1 1 0 -0.0052 36 0 0 0 - - - - - 4.131 1 221125_WJC_METTL3_EV_vs_WT_F04.24721.24721.3 8.96E-09 23/60 R.LQQELDDLLVDLDHQR.Q sp|P35579|MYH9_HUMAN 1 1948.9854 1.04 56696 24721 3 1948.986314 650.6691 Myosin-9 OS=Homo sapiens OX=9606 GN=MYH9 PE=1 SV=4 4.03 3861.9 - 807353 - - - 0.4587 - 3.791 0.608 - 884.8 1 2 0 0.0009 16 0 0 0 1.96E+07 1.88E+07 - - - 8.7377 1 221125_WJC_METTL3_EV_vs_WT_F04.24722.24722.4 6.44E-06 16/120 R.DSSQVHPLAVLLLTDGDVHIR[166.11].D "sp|Q7L2E3|DHX30_HUMAN,tr|H7BXY3|H7BXY3_HUMAN" 2 2294.2258 1.13 56697 24722 4 2294.228035 574.5637 ATP-dependent RNA helicase DHX30 OS=Homo sapiens OX=9606 GN=DHX30 PE=1 SV=1 5.13 3862.1 - 803710 - - - 0.9676 - 3.631 0.519 - 160.4 1 2 0 0.0022 21 0 0 0 1.88E+07 1.66E+07 - - - 4.1691 1 221125_WJC_METTL3_EV_vs_WT_F04.24723.24723.4 2.85E-08 33/198 K.FGLSSGLSNPVSLTPFQFGVSNLGQEEKKEELPK.S sp|P49790|NU153_HUMAN 1 3662.8832 2.38 56698 24723 4 3662.883928 916.7281 Nuclear pore complex protein Nup153 OS=Homo sapiens OX=9606 GN=NUP153 PE=1 SV=2 4.95 3862.2 - 735380 - - - 0.2007 - 5.651 0.621 - 361.8 1 2 1 0.0007 34 0 0 0 8.47E+06 3.56E+06 - - - 5.1474 1 221125_WJC_METTL3_EV_vs_WT_F04.24724.24724.4 9.64E-05 19/120 R.DSSQVHPLAVLLLTDGDVHIR.D "sp|Q7L2E3|DHX30_HUMAN,tr|H7BXY3|H7BXY3_HUMAN" 2 2284.2175 1.13 56699 24724 4 2284.221846 572.0617 ATP-dependent RNA helicase DHX30 OS=Homo sapiens OX=9606 GN=DHX30 PE=1 SV=1 5.13 3862.3 - 623099 - - - 1.8829 - 3.78 0.586 - 289 1 2 0 0.0043 21 0 0 0 1.89E+07 1.67E+07 - - - 4.765 1 221125_WJC_METTL3_EV_vs_WT_F04.24725.24725.4 2.68E-05 16/240 K.KPGILGDSPLGALQPGAQPANPLLGELPAGGGLPPELPPRR.G "sp|Q8IY67|RAVR1_HUMAN,tr|E9PAU2|E9PAU2_HUMAN,tr|A0A087WZ13|A0A087WZ13_HUMAN" 3 4017.2164 1.33 56700 24725 4 4017.220849 1005.3114 Ribonucleoprotein PTB-binding 1 OS=Homo sapiens OX=9606 GN=RAVER1 PE=1 SV=1 6.18 3862.5 - 388118 - - - 1.115 - 3.143 0.556 - 43.6 1 2 0 0.0045 41 0 0 0 8.93E+06 6.73E+06 - - - 4.3931 0.9989 221125_WJC_METTL3_EV_vs_WT_F04.24729.24729.3 0.00582 Oct-84 K.KNEIMVAPDKDYFLIVIQNPTE.- "sp|Q9NP97|DLRB1_HUMAN,tr|B1AKR6|B1AKR6_HUMAN" 2 2576.3196 3.34 56702 24729 3 2576.316896 859.7805 Dynein light chain roadblock-type 1 OS=Homo sapiens OX=9606 GN=DYNLRB1 PE=1 SV=3 4.54 3863 - 797382 - - - -1.06 - 2.101 0.371 - 59.9 1 2 1 -0.0027 22 0 0 0 1.42E+07 4.25E+06 - - - 4.4357 0.9999 221125_WJC_METTL3_EV_vs_WT_F04.24731.24731.3 3.27E-08 23/80 -.MRYVASYLLAALGGNSSPSAK.D sp|P05387|RLA2_HUMAN 1 2155.1096 1.22 56704 24731 3 2155.110074 719.3771 60S acidic ribosomal protein P2 OS=Homo sapiens OX=9606 GN=RPLP2 PE=1 SV=1 9.7 3863.2 - 5.05E+06 - - - 0.232 - 4.19 0.518 - 612.9 1 2 1 0.0005 21 0 0 0 8.78E+07 7.19E+07 - - - 7.7499 1 221125_WJC_METTL3_EV_vs_WT_F04.24732.24732.4 3.07E-07 27/228 K.SGLVGGQLSGGLGLPPGK[136.11]PPSSSPLTGASPPSFLQGLC[160.03]R[166.11].D sp|Q9H7S9|ZN703_HUMAN 1 3747.9737 1.23 56705 24732 4 3747.971735 938.0007 Zinc finger protein 703 OS=Homo sapiens OX=9606 GN=ZNF703 PE=1 SV=1 9.5 3863.3 - 1.67E+06 - - - -0.5243 - 4.404 0.47 - 261 1 2 0 -0.002 39 0 0 0 6.98E+07 5.69E+07 - - - 3.7464 0.9998 221125_WJC_METTL3_EV_vs_WT_F04.24734.24734.3 2.93E-08 Nov-68 K.EFEEASSKLEEFVNGLDK.Q sp|Q5VT52|RPRD2_HUMAN 1 2069.9793 1.19 56707 24734 3 2069.973652 691.0004 Regulation of nuclear pre-mRNA domain-containing protein 2 OS=Homo sapiens OX=9606 GN=RPRD2 PE=1 SV=1 4.14 3863.6 - 571050 - - - -2.7435 - 2.683 0.585 - 117.6 1 2 1 -0.0057 18 0 0 0 5.58E+06 4.71E+06 - - - 7.5182 1 221125_WJC_METTL3_EV_vs_WT_F04.24735.24735.2 2.89E-12 16/30 K.K[136.11]VSQEILELLNTTTAK[136.11].E "sp|Q86U44|MTA70_HUMAN,tr|H0YFV6|H0YFV6_HUMAN" 2 1803.0324 0.001 56708 24735 2 1803.037416 902.5235 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 6.14 3863.7 - 311330 - - - 2.7653 - 3.478 0.674 - 638.7 1 2 0 0.005 16 0 0 0 0.00E+00 9.92E+06 - - - 7.0821 1 221125_WJC_METTL3_EV_vs_WT_F04.24739.24739.4 2.54E-08 14/96 R.THNLEPYFESFINNLRR.R sp|P04264|K2C1_HUMAN 1 2149.0705 395.26 56710 24739 4 2149.070376 538.2749 "Keratin, type II cytoskeletal 1 OS=Homo sapiens OX=9606 GN=KRT1 PE=1 SV=6" 6.42 3864.2 - 483726 - - - -0.0517 - 2.748 0.595 - 217.2 1 2 0 -0.0001 17 0 0 0 5.85E+07 1.48E+05 - - - 4.7558 1 221125_WJC_METTL3_EV_vs_WT_F04.24742.24742.4 2.92E-10 21/234 K.LLSGYPSSSSLASAAAAAMAC[160.03]HMHIPTSGAPGSPGTLALR.S sp|Q96F45|ZN503_HUMAN 1 3865.8913 1.93 56713 24742 4 3865.889365 967.4801 Zinc finger protein 503 OS=Homo sapiens OX=9606 GN=ZNF503 PE=1 SV=1 8.24 3864.6 - 717704 - - - -0.5132 - 3.681 0.627 - 125.9 1 2 0 -0.002 40 0 0 0 1.41E+07 7.28E+06 - - - 5.059 0.9997 221125_WJC_METTL3_EV_vs_WT_F04.24748.24748.4 1.00E-05 11/114 K.ESKKEDLVFIFWAPESAPLK.S "sp|P23528|COF1_HUMAN,sp|Q9Y281|COF2_HUMAN,tr|E9PP50|E9PP50_HUMAN,tr|G3V1A4|G3V1A4_HUMAN,tr|E9PQB7|E9PQB7_HUMAN,tr|E9PK25|E9PK25_HUMAN" 6 2333.2307 1.43 56717 24748 4 2333.230549 584.315 Cofilin-1 OS=Homo sapiens OX=9606 GN=CFL1 PE=1 SV=3 4.87 3865.6 - 792539 - - - -0.0797 - 2.647 0.443 - 77.6 1 2 1 -0.0002 20 0 0 0 2.31E+07 1.62E+07 - - - 3.4073 1 221125_WJC_METTL3_EV_vs_WT_F04.24752.24752.3 1.60E-10 15/60 R.KLTFLYLANDVIQNSK.R "sp|Q96P16|RPR1A_HUMAN,sp|Q9NQG5|RPR1B_HUMAN,tr|E9PIQ9|E9PIQ9_HUMAN,tr|A0A0C4DGQ6|A0A0C4DGQ6_HUMAN" 4 1866.0251 2.44 56719 24752 3 1866.027662 623.0156 Regulation of nuclear pre-mRNA domain-containing protein 1A OS=Homo sapiens OX=9606 GN=RPRD1A PE=1 SV=1 8.5 3866.1 - 402083 - - - 1.373 - 3.243 0.492 - 330.5 1 2 0 0.0026 16 0 0 0 1.41E+07 5.78E+06 - - - 7.0433 1 221125_WJC_METTL3_EV_vs_WT_F04.24754.24754.3 1.54E-09 31/88 K.TGIASSILDAISQGSESQHALEK[136.11].C sp|Q9HCJ3|RAVR2_HUMAN 1 2349.1903 1.46 56720 24754 3 2349.191651 784.0707 Ribonucleoprotein PTB-binding 2 OS=Homo sapiens OX=9606 GN=RAVER2 PE=1 SV=2 4.65 3866.3 - 6.38E+06 - - - 0.5606 - 5.237 0.572 - 1080.7 1 2 0 0.0013 23 0 0 0 1.40E+08 9.62E+07 - - - 8.8012 0.9999 221125_WJC_METTL3_EV_vs_WT_F04.24756.24756.3 7.87E-08 Dec-88 K.EQELNQSISEK[136.11]ETLIAEIEELDR[166.11].Q "sp|Q15643|TRIPB_HUMAN,tr|H0YJ97|H0YJ97_HUMAN" 2 2733.3675 2.03 56722 24756 3 2733.367192 912.1298 Thyroid receptor-interacting protein 11 OS=Homo sapiens OX=9606 GN=TRIP11 PE=1 SV=3 3.99 3866.6 - 687052 - - - -0.12 - 2.652 0.594 - 121.8 1 2 1 -0.0003 23 0 0 0 1.63E+07 8.06E+06 - - - 7.4505 1 221125_WJC_METTL3_EV_vs_WT_F04.24759.24759.3 6.58E-15 21/80 R.QAAAFTASVQHVEAELSAQIR.Y "sp|Q9P086|MED11_HUMAN,tr|I3L2Q0|I3L2Q0_HUMAN,tr|I3L3E8|I3L3E8_HUMAN" 3 2226.1393 1.32 56723 24759 3 2226.14617 743.0537 Mediator of RNA polymerase II transcription subunit 11 OS=Homo sapiens OX=9606 GN=MED11 PE=1 SV=2 5.4 3866.9 - 475246 - - - 3.0883 - 4.206 0.646 - 524.4 1 2 0 0.0069 21 0 0 0 4.52E+06 3.44E+06 - - - 9.1843 1 221125_WJC_METTL3_EV_vs_WT_F04.24761.24761.3 7.60E-12 20/88 K.EQELNQSISEKETLIAEIEELDR.Q "sp|Q15643|TRIPB_HUMAN,tr|H0YJ97|H0YJ97_HUMAN" 2 2715.345 2.03 56724 24761 3 2715.343343 906.1223 Thyroid receptor-interacting protein 11 OS=Homo sapiens OX=9606 GN=TRIP11 PE=1 SV=3 3.99 3867.2 - 848991 - - - -0.6286 - 3.437 0.654 - 344.9 1 2 1 -0.0017 23 0 0 0 1.63E+07 8.06E+06 - - - 8.7273 1 221125_WJC_METTL3_EV_vs_WT_F04.24763.24763.3 2.53E-13 25/60 V.RQNLEPLFEQYINNLR.R "sp|P48668|K2C6C_HUMAN,sp|P04259|K2C6B_HUMAN,sp|P13647|K2C5_HUMAN,sp|P02538|K2C6A_HUMAN,tr|F8W0C6|F8W0C6_HUMAN" 5 2046.0647 10947.4 56726 24763 3 2046.065112 683.0288 "Keratin, type II cytoskeletal 6C OS=Homo sapiens OX=9606 GN=KRT6C PE=1 SV=3" 6.14 3867.4 - 2.04E+06 - - - 0.2146 - 4.984 0.545 - 1089.4 1 1 0 0.0004 16 0 0 0 5.25E+08 4.79E+04 - - - 8.7375 0.9987 221125_WJC_METTL3_EV_vs_WT_F04.24764.24764.4 0.0324 8/132 K.TGIASSILDAISQGSESQHALEK.C sp|Q9HCJ3|RAVR2_HUMAN 1 2341.1761 2.14 56727 24764 4 2341.17087 586.3013 Ribonucleoprotein PTB-binding 2 OS=Homo sapiens OX=9606 GN=RAVER2 PE=1 SV=2 4.65 3867.5 - 306092 - - - -2.2484 - 2.133 0.31 - 41.1 1 2 0 -0.0053 23 0 0 0 4.54E+06 2.12E+06 - - - 2.1682 1 221125_WJC_METTL3_EV_vs_WT_F04.24770.24770.4 1.42E-07 16/150 R.KLMSDPDSSIIDFYPEDFAIDLNGKK.Y sp|Q9H0D6|XRN2_HUMAN 1 2957.4368 2.74 56731 24770 4 2957.43105 740.3665 5'-3' exoribonuclease 2 OS=Homo sapiens OX=9606 GN=XRN2 PE=1 SV=1 4.17 3868.3 - 490168 - - - -1.9585 - 2.724 0.543 - 136.7 1 2 0 -0.0058 26 0 0 0 8.27E+06 3.02E+06 - - - 4.2668 1 221125_WJC_METTL3_EV_vs_WT_F04.24775.24775.4 1.88E-10 21/108 R.ADLEMQIENLKEELAYLKK.N "sp|Q04695|K1C17_HUMAN,tr|K7EPJ9|K7EPJ9_HUMAN,tr|F5GWP8|F5GWP8_HUMAN" 3 2277.1926 999 56734 24775 4 2277.197239 570.3054 "Keratin, type I cytoskeletal 17 OS=Homo sapiens OX=9606 GN=KRT17 PE=1 SV=2" 4.59 3869 - 1.02E+06 - - - 2.0218 - 4.193 0.647 - 489.7 1 2 1 0.0046 19 0 0 0 1.49E+08 0.00E+00 - - - 5.3411 1 221125_WJC_METTL3_EV_vs_WT_F04.24776.24776.4 5.76E-13 21/174 R.K[136.11]EPFTLEAYYSSPQDLPYPDPAIAQFSVQK[136.11].V "sp|P34932|HSP74_HUMAN,tr|A0A087WYC1|A0A087WYC1_HUMAN" 2 3444.71 0.23 56735 24776 4 3444.712555 862.1848 Heat shock 70 kDa protein 4 OS=Homo sapiens OX=9606 GN=HSPA4 PE=1 SV=4 4.32 3869.1 - 712246 - - - 0.7301 - 3.677 0.703 - 223.6 1 2 0 0.0025 30 0 0 0 1.38E+06 5.88E+06 - - - 5.7427 1 221125_WJC_METTL3_EV_vs_WT_F04.24777.24777.3 4.71E-14 25/116 R.K[136.11]EPFTLEAYYSSPQDLPYPDPAIAQFSVQK[136.11].V "sp|P34932|HSP74_HUMAN,tr|A0A087WYC1|A0A087WYC1_HUMAN" 2 3444.71 0.04 56736 24777 3 3444.716571 1149.244 Heat shock 70 kDa protein 4 OS=Homo sapiens OX=9606 GN=HSPA4 PE=1 SV=4 4.32 3869.2 - 532096 - - - 1.896 - 3.829 0.737 - 529.2 1 2 0 0.0065 30 0 0 0 3.21E+05 8.82E+06 - - - 9.8439 0.9998 221125_WJC_METTL3_EV_vs_WT_F04.24781.24781.4 5.23E-07 14/114 K.ESK[136.11]K[136.11]EDLVFIFWAPESAPLK[136.11].S "sp|P23528|COF1_HUMAN,sp|Q9Y281|COF2_HUMAN,tr|E9PP50|E9PP50_HUMAN,tr|G3V1A4|G3V1A4_HUMAN,tr|E9PQB7|E9PQB7_HUMAN,tr|E9PK25|E9PK25_HUMAN" 6 2357.2733 1.43 56738 24781 4 2357.273835 590.3256 Cofilin-1 OS=Homo sapiens OX=9606 GN=CFL1 PE=1 SV=3 4.87 3869.8 - 766676 - - - 0.2121 - 2.814 0.471 - 111.2 1 2 1 0.0005 20 0 0 0 2.31E+07 1.62E+07 - - - 3.6713 1 221125_WJC_METTL3_EV_vs_WT_F04.24782.24782.3 8.14E-07 20/64 K.LNDLEEALQQAKEDLAR.L sp|P35908|K22E_HUMAN 1 1954.996 19.01 56739 24782 3 1954.997624 652.6726 "Keratin, type II cytoskeletal 2 epidermal OS=Homo sapiens OX=9606 GN=KRT2 PE=1 SV=2" 4.18 3869.9 - 787392 - - - 0.8389 - 4.483 0.558 - 588 1 2 1 0.0016 17 0 0 0 1.61E+07 8.47E+05 - - - 8.5509 0.9993 221125_WJC_METTL3_EV_vs_WT_F04.24783.24783.3 6.74E-05 13/112 R.EIPDPDSAELLC[160.03]C[160.03]TFQPVNNNLTVVGNAK.H sp|Q9H1Z4|WDR13_HUMAN 1 3214.5275 1.63 56740 24783 3 3214.510859 1072.5164 WD repeat-containing protein 13 OS=Homo sapiens OX=9606 GN=WDR13 PE=1 SV=2 3.92 3870 - 626328 - - - -5.1659 - 2.321 0.515 - 103.3 1 2 0 -0.0166 29 0 0 0 4.14E+06 2.53E+06 - - - 6.2143 1 221125_WJC_METTL3_EV_vs_WT_F04.24784.24784.3 1.12E-16 19/172 R.LGSAGGLGSTLGGSSYSSC[160.03]YSFGSGGGYGSSFGGVDGLLAGGEK.A "sp|Q04695|K1C17_HUMAN,tr|K7EPJ9|K7EPJ9_HUMAN" 2 4023.8069 999 56741 24784 3 4023.80458 1342.2762 "Keratin, type I cytoskeletal 17 OS=Homo sapiens OX=9606 GN=KRT17 PE=1 SV=2" 4.37 3870.1 - 568208 - - - -0.5691 - 3.538 0.789 - 181.2 1 2 0 -0.0023 44 0 0 0 5.55E+06 0.00E+00 - - - 10.2429 1 221125_WJC_METTL3_EV_vs_WT_F04.24788.24788.3 1.51E-08 22/120 R.TDPVPEEGEDVAATISATETLSEEEQEELRR.E "sp|P55327|TPD52_HUMAN,tr|H0YC44|H0YC44_HUMAN,tr|E5RFR7|E5RFR7_HUMAN,tr|H0YC42|H0YC42_HUMAN" 4 3429.5907 0.95 56743 24788 3 3429.587837 1144.2042 Tumor protein D52 OS=Homo sapiens OX=9606 GN=TPD52 PE=1 SV=2 3.8 3870.7 - 863075 - - - -0.8383 - 2.973 0.632 - 157.5 1 2 0 -0.0029 31 0 0 0 1.01E+07 1.06E+07 - - - 8.0921 1 221125_WJC_METTL3_EV_vs_WT_F04.24789.24789.3 4.26E-14 30/96 K.AGIEAGNINITSGEVFEIEEHISER.Q sp|O43172|PRP4_HUMAN 1 2713.3195 4.38 56744 24789 3 2713.31988 905.4471 U4\U6 small nuclear ribonucleoprotein Prp4 OS=Homo sapiens OX=9606 GN=PRPF4 PE=1 SV=2 4.2 3870.7 - 2.50E+06 - - - 0.1386 - 5.391 0.683 - 1220.6 1 2 0 0.0004 25 0 0 0 3.51E+07 8.03E+06 - - - 10.0306 1 221125_WJC_METTL3_EV_vs_WT_F04.24792.24792.3 6.65E-09 22/72 R.ADLEMQIENLKEELAYLKK.N "sp|Q04695|K1C17_HUMAN,tr|K7EPJ9|K7EPJ9_HUMAN,tr|F5GWP8|F5GWP8_HUMAN" 3 2277.1926 999 56747 24792 3 2277.196349 760.0715 "Keratin, type I cytoskeletal 17 OS=Homo sapiens OX=9606 GN=KRT17 PE=1 SV=2" 4.59 3871.1 - 703880 - - - 1.631 - 4.581 0.595 - 822.4 1 2 1 0.0037 19 0 0 0 4.99E+07 0.00E+00 - - - 8.9117 1 221125_WJC_METTL3_EV_vs_WT_F04.24801.24801.3 5.06E-12 23/88 K.SSVLIAQQTDTSDPEK[136.11]VVSAFLK[136.11].V sp|P46060|RAGP1_HUMAN 1 2478.3188 1.78 56753 24801 3 2478.315552 827.1136 Ran GTPase-activating protein 1 OS=Homo sapiens OX=9606 GN=RANGAP1 PE=1 SV=1 4.56 3872.2 - 787334 - - - -1.3247 - 4.375 0.681 - 515.8 1 2 1 -0.0033 23 0 0 0 1.49E+07 8.37E+06 - - - 9.594 1 221125_WJC_METTL3_EV_vs_WT_F04.24804.24804.4 8.94E-07 17/180 R.TDPVPEEGEDVAATISATETLSEEEQEELRR.E "sp|P55327|TPD52_HUMAN,tr|H0YC44|H0YC44_HUMAN,tr|E5RFR7|E5RFR7_HUMAN,tr|H0YC42|H0YC42_HUMAN" 4 3429.5907 1.28 56754 24804 4 3429.590545 858.405 Tumor protein D52 OS=Homo sapiens OX=9606 GN=TPD52 PE=1 SV=2 3.8 3872.6 - 1.02E+06 - - - -0.0487 - 3.104 0.488 - 89.8 1 2 0 -0.0002 31 0 0 0 7.53E+06 5.87E+06 - - - 3.8178 1 221125_WJC_METTL3_EV_vs_WT_F04.24805.24805.3 4.91E-11 20/96 K.AGIEAGNINITSGEVFEIEEHISER[166.11].Q sp|O43172|PRP4_HUMAN 1 2723.3278 4.23 56755 24805 3 2723.329929 908.7832 U4\U6 small nuclear ribonucleoprotein Prp4 OS=Homo sapiens OX=9606 GN=PRPF4 PE=1 SV=2 4.2 3872.8 - 449495 - - - 0.7913 - 4.06 0.621 - 384.1 1 2 0 0.0022 25 0 0 0 3.40E+07 8.03E+06 - - - 8.6866 1 221125_WJC_METTL3_EV_vs_WT_F04.24806.24806.3 8.49E-05 13/64 R.THNLEPYFESFINNLRR.R sp|P04264|K2C1_HUMAN 1 2149.0705 15 56756 24806 3 2149.072202 717.3641 "Keratin, type II cytoskeletal 1 OS=Homo sapiens OX=9606 GN=KRT1 PE=1 SV=6" 6.42 3872.9 - 1.56E+06 - - - 0.798 - 2.383 0.508 - 211.3 1 2 0 0.0017 17 0 0 0 4.06E+07 2.70E+06 - - - 6.397 0.9809 221125_WJC_METTL3_EV_vs_WT_F04.24809.24809.2 6.89E-05 30-Sep V.RQNLEPLFEQYINNLR.R "sp|P48668|K2C6C_HUMAN,sp|P04259|K2C6B_HUMAN,sp|P13647|K2C5_HUMAN,sp|P02538|K2C6A_HUMAN,tr|F8W0C6|F8W0C6_HUMAN" 5 2046.0647 999 56759 24809 2 2046.063349 1024.0396 "Keratin, type II cytoskeletal 6C OS=Homo sapiens OX=9606 GN=KRT6C PE=1 SV=3" 6.14 3873.3 - 564156 - - - -0.6471 - 1.656 0.443 - 53.8 1 1 0 -0.0013 16 0 0 0 1.38E+07 0.00E+00 - - - 3.5527 0.9999 221125_WJC_METTL3_EV_vs_WT_F04.24814.24814.3 1.04E-06 15/52 R.ARDDLITDLLNEAK.Q "sp|P36543|VATE1_HUMAN,tr|C9J8H1|C9J8H1_HUMAN" 2 1585.8312 1.5 56762 24814 3 1585.829698 529.6177 V-type proton ATPase subunit E 1 OS=Homo sapiens OX=9606 GN=ATP6V1E1 PE=1 SV=1 4.23 3873.9 - 673601 - - - -0.9162 - 3.219 0.478 - 372.4 1 2 1 -0.0015 14 0 0 0 1.05E+07 6.99E+06 - - - 6.9757 1 221125_WJC_METTL3_EV_vs_WT_F04.24815.24815.3 2.07E-11 24/80 R.ESEEENLNKSEISQVFEIALK.R "sp|O95793|STAU1_HUMAN,tr|Q5JW30|Q5JW30_HUMAN,tr|Q5JW28|Q5JW28_HUMAN" 3 2435.2068 3.87 56763 24815 3 2435.209198 812.7429 Double-stranded RNA-binding protein Staufen homolog 1 OS=Homo sapiens OX=9606 GN=STAU1 PE=1 SV=2 4.21 3874.1 - 984697 - - - 0.9991 - 3.955 0.668 - 740.2 1 2 1 0.0024 21 0 0 0 4.85E+07 1.25E+07 - - - 9.2833 0.9999 221125_WJC_METTL3_EV_vs_WT_F04.24817.24817.3 1.79E-07 17/52 R.AR[166.11]DDLITDLLNEAK[136.11].Q "sp|P36543|VATE1_HUMAN,tr|C9J8H1|C9J8H1_HUMAN" 2 1603.8536 1.5 56765 24817 3 1603.851075 535.6252 V-type proton ATPase subunit E 1 OS=Homo sapiens OX=9606 GN=ATP6V1E1 PE=1 SV=1 4.23 3874.3 - 462125 - - - -1.5874 - 2.658 0.521 - 367.6 1 2 1 -0.0025 14 0 0 0 1.05E+07 6.99E+06 - - - 6.9459 0.9995 221125_WJC_METTL3_EV_vs_WT_F04.24819.24819.3 0.000704 Aug-56 K.ITPENLPQILLQLK[136.11]R[166.11].R "sp|P43243|MATR3_HUMAN,tr|A8MXP9|A8MXP9_HUMAN,tr|D6R991|D6R991_HUMAN,tr|A0A0R4J2E8|A0A0R4J2E8_HUMAN,tr|D6REM6|D6REM6_HUMAN" 5 1793.0894 1.96 56767 24819 3 1793.089498 598.7037 Matrin-3 OS=Homo sapiens OX=9606 GN=MATR3 PE=1 SV=2 8.75 3874.6 - 197275 - - - 0.0686 - 1.586 0.368 - 97.8 1 2 0 0.0001 15 0 0 0 3.31E+06 1.69E+06 - - - 3.8463 1 221125_WJC_METTL3_EV_vs_WT_F04.24823.24823.3 0.0116 24/96 R.GLEDGEAGEEEEKEPLPSLDVFLSR.Y "sp|Q96DF8|ESS2_HUMAN,tr|F8WEF8|F8WEF8_HUMAN" 2 2744.3029 2.13 56769 24823 3 2744.299852 915.7749 Splicing factor ESS-2 homolog OS=Homo sapiens OX=9606 GN=ESS2 PE=1 SV=1 3.89 3875.1 - 2.35E+06 - - - -1.0924 - 4.277 0.629 - 405.6 1 2 1 -0.003 25 0 0 0 3.68E+07 1.72E+07 - - - 8.8953 1 221125_WJC_METTL3_EV_vs_WT_F04.24824.24824.3 4.01E-16 24/120 K.AFLADPSAFVAAAPVAAATTAAPAAAAAPAK.V "sp|P05388|RLA0_HUMAN,tr|F8VWS0|F8VWS0_HUMAN,tr|F8W1K8|F8W1K8_HUMAN" 3 2751.4596 1.91 56770 24824 3 2751.462791 918.1605 60S acidic ribosomal protein P0 OS=Homo sapiens OX=9606 GN=RPLP0 PE=1 SV=1 5.88 3875.2 - 686515 - - - 1.1721 - 4.787 0.721 - 479.1 1 2 0 0.0032 31 0 0 0 1.01E+07 5.32E+06 - - - 10.1801 1 221125_WJC_METTL3_EV_vs_WT_F04.24826.24826.3 3.13E-10 20/88 K.ANC[160.03]SDNEFTQALTAAIPPESLTR.G "sp|Q16891|MIC60_HUMAN,tr|B9A067|B9A067_HUMAN,tr|C9J406|C9J406_HUMAN,tr|H7C463|H7C463_HUMAN" 4 2505.1806 1.31 56772 24826 3 2505.179752 836.0675 MICOS complex subunit MIC60 OS=Homo sapiens OX=9606 GN=IMMT PE=1 SV=1 4.14 3875.5 - 1.02E+06 - - - -0.3253 - 3.439 0.663 - 226.8 1 2 0 -0.0008 23 0 0 0 2.02E+07 1.54E+07 - - - 8.8292 0.9983 221125_WJC_METTL3_EV_vs_WT_F04.24830.24830.4 7.84E-05 15/90 V.RQNLEPLFEQYINNLR.R "sp|P48668|K2C6C_HUMAN,sp|P04259|K2C6B_HUMAN,sp|P13647|K2C5_HUMAN,sp|P02538|K2C6A_HUMAN,tr|F8W0C6|F8W0C6_HUMAN" 5 2046.0647 999 56774 24830 4 2046.061889 512.5234 "Keratin, type II cytoskeletal 6C OS=Homo sapiens OX=9606 GN=KRT6C PE=1 SV=3" 6.14 3876 - 327913 - - - -1.3607 - 3.126 0.605 - 251.7 1 1 0 -0.0028 16 0 0 0 8.48E+06 0.00E+00 - - - 4.8926 0.9998 221125_WJC_METTL3_EV_vs_WT_F04.24834.24834.3 1.69E-06 11/112 K.MK[136.11]ETAENYLGHTAK[136.11]NAVITVPAYFNDSQR[166.11].Q "sp|P38646|GRP75_HUMAN,tr|H0Y8K0|H0Y8K0_HUMAN,tr|A0A7I2V2S7|A0A7I2V2S7_HUMAN,tr|A0A7I2V2G2|A0A7I2V2G2_HUMAN,tr|A0A7I2V3F7|A0A7I2V3F7_HUMAN,tr|A0A7I2YQB2|A0A7I2YQB2_HUMAN,tr|D6RCD7|D6RCD7_HUMAN" 7 3293.6349 0 56777 24834 3 3293.636741 1098.8856 "Stress-70 protein, mitochondrial OS=Homo sapiens OX=9606 GN=HSPA9 PE=1 SV=2" 6.51 3876.5 - 490594 - - - 0.5495 - 2.322 0.488 - 41 1 2 2 0.0018 29 0 0 0 1.67E+06 3.63E+08 - - - 5.9183 1 221125_WJC_METTL3_EV_vs_WT_F04.24835.24835.3 6.73E-12 18/96 R.DDSGMVAPSNIFHQPMASGFVDFSK.G "sp|Q8IWZ3|ANKH1_HUMAN,tr|A0A0A0MQZ8|A0A0A0MQZ8_HUMAN,tr|H0Y7Y3|H0Y7Y3_HUMAN,tr|H0Y4P6|H0Y4P6_HUMAN,tr|H7C2E1|H7C2E1_HUMAN" 5 2683.2047 1.77 56778 24835 3 2683.203264 895.4088 Ankyrin repeat and KH domain-containing protein 1 OS=Homo sapiens OX=9606 GN=ANKHD1 PE=1 SV=1 4.41 3876.6 - 364324 - - - -0.5251 - 3.569 0.743 - 318.5 1 2 0 -0.0014 25 0 0 0 1.92E+07 1.08E+07 - - - 9.7504 1 221125_WJC_METTL3_EV_vs_WT_F04.24836.24836.3 5.11E-13 19/76 K.VHNGMDDLILDGHNILDGLR.T "sp|O14653|GOSR2_HUMAN,tr|I3NI02|I3NI02_HUMAN,tr|E7EQ34|E7EQ34_HUMAN,tr|A0A1W2PPP5|A0A1W2PPP5_HUMAN,tr|A0A1W2PPG5|A0A1W2PPG5_HUMAN,tr|I3L0K1|I3L0K1_HUMAN,tr|A0A1W2PP28|A0A1W2PP28_HUMAN,tr|A0A1W2PRC2|A0A1W2PRC2_HUMAN,tr|A0A1W2PQQ4|A0A1W2PQQ4_HUMAN,tr|A0A1W2PQP2|A0A1W2PQP2_HUMAN,tr|A0A1X7SBU8|A0A1X7SBU8_HUMAN,tr|A0A1W2PS81|A0A1W2PS81_HUMAN,tr|I3L4Z6|I3L4Z6_HUMAN,tr|A0A1W2PPJ0|A0A1W2PPJ0_HUMAN,tr|A0A1W2PPG1|A0A1W2PPG1_HUMAN,tr|A0A1W2PRV0|A0A1W2PRV0_HUMAN,tr|A0A1W2PQS3|A0A1W2PQS3_HUMAN,tr|A0A1W2PNV3|A0A1W2PNV3_HUMAN,tr|A0A1W2PQM3|A0A1W2PQM3_HUMAN,tr|A0A1W2PRE6|A0A1W2PRE6_HUMAN,tr|A0A1W2PS12|A0A1W2PS12_HUMAN,tr|A0A1W2PRL0|A0A1W2PRL0_HUMAN" 22 2216.1008 0.85 56779 24836 3 2216.098383 739.7075 Golgi SNAP receptor complex member 2 OS=Homo sapiens OX=9606 GN=GOSR2 PE=1 SV=2 4.54 3876.8 - 353811 - - - -1.0911 - 3.913 0.719 - 393.6 1 2 0 -0.0024 20 0 0 0 4.85E+06 5.72E+06 - - - 9.8653 1 221125_WJC_METTL3_EV_vs_WT_F04.24841.24841.4 2.00E-10 23/114 K.VHNGMDDLILDGHNILDGLR.T "sp|O14653|GOSR2_HUMAN,tr|I3NI02|I3NI02_HUMAN,tr|E7EQ34|E7EQ34_HUMAN,tr|A0A1W2PPP5|A0A1W2PPP5_HUMAN,tr|A0A1W2PPG5|A0A1W2PPG5_HUMAN,tr|I3L0K1|I3L0K1_HUMAN,tr|A0A1W2PP28|A0A1W2PP28_HUMAN,tr|A0A1W2PRC2|A0A1W2PRC2_HUMAN,tr|A0A1W2PQQ4|A0A1W2PQQ4_HUMAN,tr|A0A1W2PQP2|A0A1W2PQP2_HUMAN,tr|A0A1X7SBU8|A0A1X7SBU8_HUMAN,tr|A0A1W2PS81|A0A1W2PS81_HUMAN,tr|I3L4Z6|I3L4Z6_HUMAN,tr|A0A1W2PPJ0|A0A1W2PPJ0_HUMAN,tr|A0A1W2PPG1|A0A1W2PPG1_HUMAN,tr|A0A1W2PRV0|A0A1W2PRV0_HUMAN,tr|A0A1W2PQS3|A0A1W2PQS3_HUMAN,tr|A0A1W2PNV3|A0A1W2PNV3_HUMAN,tr|A0A1W2PQM3|A0A1W2PQM3_HUMAN,tr|A0A1W2PRE6|A0A1W2PRE6_HUMAN,tr|A0A1W2PS12|A0A1W2PS12_HUMAN,tr|A0A1W2PRL0|A0A1W2PRL0_HUMAN" 22 2216.1008 1.43 56782 24841 4 2216.102611 555.0325 Golgi SNAP receptor complex member 2 OS=Homo sapiens OX=9606 GN=GOSR2 PE=1 SV=2 4.54 3877.4 - 548876 - - - 0.8167 - 4.385 0.656 - 552.7 1 2 0 0.0018 20 0 0 0 5.16E+06 3.61E+06 - - - 5.4295 1 221125_WJC_METTL3_EV_vs_WT_F04.24842.24842.4 4.57E-13 19/114 K.VHNGMDDLILDGHNILDGLR[166.11].T "sp|O14653|GOSR2_HUMAN,tr|I3NI02|I3NI02_HUMAN,tr|E7EQ34|E7EQ34_HUMAN,tr|A0A1W2PPP5|A0A1W2PPP5_HUMAN,tr|A0A1W2PPG5|A0A1W2PPG5_HUMAN,tr|I3L0K1|I3L0K1_HUMAN,tr|A0A1W2PP28|A0A1W2PP28_HUMAN,tr|A0A1W2PRC2|A0A1W2PRC2_HUMAN,tr|A0A1W2PQQ4|A0A1W2PQQ4_HUMAN,tr|A0A1W2PQP2|A0A1W2PQP2_HUMAN,tr|A0A1X7SBU8|A0A1X7SBU8_HUMAN,tr|A0A1W2PS81|A0A1W2PS81_HUMAN,tr|I3L4Z6|I3L4Z6_HUMAN,tr|A0A1W2PPJ0|A0A1W2PPJ0_HUMAN,tr|A0A1W2PPG1|A0A1W2PPG1_HUMAN,tr|A0A1W2PRV0|A0A1W2PRV0_HUMAN,tr|A0A1W2PQS3|A0A1W2PQS3_HUMAN,tr|A0A1W2PNV3|A0A1W2PNV3_HUMAN,tr|A0A1W2PQM3|A0A1W2PQM3_HUMAN,tr|A0A1W2PRE6|A0A1W2PRE6_HUMAN,tr|A0A1W2PS12|A0A1W2PS12_HUMAN,tr|A0A1W2PRL0|A0A1W2PRL0_HUMAN" 22 2226.1091 1.43 56783 24842 4 2226.109133 557.5345 Golgi SNAP receptor complex member 2 OS=Homo sapiens OX=9606 GN=GOSR2 PE=1 SV=2 4.54 3877.5 - 306911 - - - 0.0279 - 4.008 0.636 - 282.5 1 2 0 0.0001 20 0 0 0 5.16E+06 3.61E+06 - - - 5.2259 1 221125_WJC_METTL3_EV_vs_WT_F04.24848.24848.3 4.93E-16 24/100 K.HWTNFVITENANDAIGILNNSASFNK.M sp|O15226|NKRF_HUMAN 1 2889.4046 1.23 56787 24848 3 2889.408431 964.1421 NF-kappa-B-repressing factor OS=Homo sapiens OX=9606 GN=NKRF PE=1 SV=2 5.32 3878.2 - 600601 - - - 1.3359 - 4.568 0.732 - 557.1 1 2 0 0.0039 26 0 0 0 5.25E+06 4.27E+06 - - - 10.1948 0.9999 221125_WJC_METTL3_EV_vs_WT_F04.24850.24850.3 2.50E-05 Nov-76 K.VHNGMDDLILDGHNILDGLR[166.11].T "sp|O14653|GOSR2_HUMAN,tr|I3NI02|I3NI02_HUMAN,tr|E7EQ34|E7EQ34_HUMAN,tr|A0A1W2PPP5|A0A1W2PPP5_HUMAN,tr|A0A1W2PPG5|A0A1W2PPG5_HUMAN,tr|I3L0K1|I3L0K1_HUMAN,tr|A0A1W2PP28|A0A1W2PP28_HUMAN,tr|A0A1W2PRC2|A0A1W2PRC2_HUMAN,tr|A0A1W2PQQ4|A0A1W2PQQ4_HUMAN,tr|A0A1W2PQP2|A0A1W2PQP2_HUMAN,tr|A0A1X7SBU8|A0A1X7SBU8_HUMAN,tr|A0A1W2PS81|A0A1W2PS81_HUMAN,tr|I3L4Z6|I3L4Z6_HUMAN,tr|A0A1W2PPJ0|A0A1W2PPJ0_HUMAN,tr|A0A1W2PPG1|A0A1W2PPG1_HUMAN,tr|A0A1W2PRV0|A0A1W2PRV0_HUMAN,tr|A0A1W2PQS3|A0A1W2PQS3_HUMAN,tr|A0A1W2PNV3|A0A1W2PNV3_HUMAN,tr|A0A1W2PQM3|A0A1W2PQM3_HUMAN,tr|A0A1W2PRE6|A0A1W2PRE6_HUMAN,tr|A0A1W2PS12|A0A1W2PS12_HUMAN,tr|A0A1W2PRL0|A0A1W2PRL0_HUMAN" 22 2226.1091 0.85 56789 24850 3 2226.106202 743.0436 Golgi SNAP receptor complex member 2 OS=Homo sapiens OX=9606 GN=GOSR2 PE=1 SV=2 4.54 3878.5 - 532097 - - - -1.2888 - 2.156 0.493 - 95.9 1 2 0 -0.0029 20 0 0 0 4.85E+06 5.72E+06 - - - 5.8995 1 221125_WJC_METTL3_EV_vs_WT_F04.24864.24864.3 2.11E-11 20/60 K.K[136.11]VSQEILELLNTTTAK[136.11].E "sp|Q86U44|MTA70_HUMAN,tr|H0YFV6|H0YFV6_HUMAN" 2 1803.0324 0 56799 24864 3 1803.032684 602.0181 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 6.14 3880.4 - 1.61E+06 - - - 0.1409 - 4.001 0.574 - 732.8 1 2 0 0.0003 16 0 0 0 1.16E+05 3.93E+07 - - - 8.4971 1 221125_WJC_METTL3_EV_vs_WT_F04.24866.24866.3 4.90E-10 19/100 R.SGPFGQIFR[166.11]PDNFVFGQSGAGNNWAK[136.11].G "sp|P04350|TBB4A_HUMAN,sp|Q9BVA1|TBB2B_HUMAN,sp|P07437|TBB5_HUMAN,sp|Q13885|TBB2A_HUMAN,sp|P68371|TBB4B_HUMAN,tr|Q5ST81|Q5ST81_HUMAN,tr|Q5JP53|Q5JP53_HUMAN,tr|M0QY85|M0QY85_HUMAN,tr|M0QZL7|M0QZL7_HUMAN,tr|M0R278|M0R278_HUMAN,tr|M0R1I1|M0R1I1_HUMAN" 11 2815.3586 0.73 56801 24866 3 2815.362771 939.4601 Tubulin beta-4A chain OS=Homo sapiens OX=9606 GN=TUBB4A PE=1 SV=2 8.46 3880.6 - 945340 - - - 1.4932 - 3.841 0.591 - 336.7 1 2 0 0.0042 26 0 0 0 3.28E+08 4.50E+08 - - - 8.2239 0.9998 221125_WJC_METTL3_EV_vs_WT_F04.24867.24867.3 2.28E-06 13/96 R.GLEDGEAGEEEEK[136.11]EPLPSLDVFLSR[166.11].Y "sp|Q96DF8|ESS2_HUMAN,tr|F8WEF8|F8WEF8_HUMAN" 2 2762.3253 2.13 56802 24867 3 2762.325757 921.7824 Splicing factor ESS-2 homolog OS=Homo sapiens OX=9606 GN=ESS2 PE=1 SV=1 3.89 3880.7 - 617402 - - - 0.1582 - 2.338 0.506 - 125.7 1 2 1 0.0004 25 0 0 0 3.68E+07 1.72E+07 - - - 6.1352 1 221125_WJC_METTL3_EV_vs_WT_F04.24869.24869.3 3.19E-13 20/116 K.ENGTVTAANASTLNDGAAALVLMTADAAK[136.11]R[166.11].L "sp|P24752|THIL_HUMAN,tr|A0A5F9ZHJ7|A0A5F9ZHJ7_HUMAN,tr|A0A5F9ZHD4|A0A5F9ZHD4_HUMAN,tr|A0A5F9ZHJ0|A0A5F9ZHJ0_HUMAN,tr|A0A5F9ZHL1|A0A5F9ZHL1_HUMAN,tr|A0A5F9ZI66|A0A5F9ZI66_HUMAN" 6 2934.4836 1.34 56804 24869 3 2934.49277 979.1685 "Acetyl-CoA acetyltransferase, mitochondrial OS=Homo sapiens OX=9606 GN=ACAT1 PE=1 SV=1" 4.56 3881 - 321543 - - - 3.1355 - 3.901 0.757 - 322.7 1 2 0 0.0092 30 0 0 0 5.02E+06 3.73E+06 - - - 10.109 0.9995 221125_WJC_METTL3_EV_vs_WT_F04.24875.24875.4 0.000172 12/168 K.MK[136.11]ETAENYLGHTAK[136.11]NAVITVPAYFNDSQR[166.11].Q "sp|P38646|GRP75_HUMAN,tr|H0Y8K0|H0Y8K0_HUMAN,tr|A0A7I2V2S7|A0A7I2V2S7_HUMAN,tr|A0A7I2V2G2|A0A7I2V2G2_HUMAN,tr|A0A7I2V3F7|A0A7I2V3F7_HUMAN,tr|A0A7I2YQB2|A0A7I2YQB2_HUMAN,tr|D6RCD7|D6RCD7_HUMAN" 7 3293.6349 0.02 56808 24875 4 3293.638375 824.416 "Stress-70 protein, mitochondrial OS=Homo sapiens OX=9606 GN=HSPA9 PE=1 SV=2" 6.51 3881.8 - 945177 - - - 1.0457 - 2.372 0.406 - 41.2 1 2 2 0.0034 29 0 0 0 2.14E+06 1.36E+08 - - - 3.0251 1 221125_WJC_METTL3_EV_vs_WT_F04.24890.24890.3 2.19E-10 24/88 K.LNNDDNVDGLLVQLPLPEHIDER[166.11].R "sp|P13995|MTDC_HUMAN,tr|A0A7I2V482|A0A7I2V482_HUMAN,tr|A0A7I2V2U6|A0A7I2V2U6_HUMAN,tr|A0A7I2YQD4|A0A7I2YQD4_HUMAN" 4 2637.3274 1.26 56821 24890 3 2637.33287 880.1164 "Bifunctional methylenetetrahydrofolate dehydrogenase\cyclohydrolase, mitochondrial OS=Homo sapiens OX=9606 GN=MTHFD2 PE=1 SV=2" 3.96 3883.5 - 2.70E+06 - - - 2.0817 - 3.937 0.648 - 422.4 1 2 0 0.0055 23 0 0 0 9.97E+07 7.93E+07 - - - 8.978 1 221125_WJC_METTL3_EV_vs_WT_F04.24891.24891.3 1.03E-06 24/96 K.DGDVTVTNDGATILSMMDVDHQIAK.L "sp|P48643|TCPE_HUMAN,tr|E9PCA1|E9PCA1_HUMAN,tr|B7ZAR1|B7ZAR1_HUMAN" 3 2645.2313 0.47 56822 24891 3 2645.232117 882.751 T-complex protein 1 subunit epsilon OS=Homo sapiens OX=9606 GN=CCT5 PE=1 SV=1 3.97 3883.6 - 2.08E+06 - - - 0.3157 - 3.583 0.601 - 442 1 2 0 0.0008 25 0 0 0 2.27E+07 4.84E+07 - - - 8.1764 1 221125_WJC_METTL3_EV_vs_WT_F04.24892.24892.3 3.80E-07 29/100 R.SGPFGQIFRPDNFVFGQSGAGNNWAK.G "sp|P04350|TBB4A_HUMAN,sp|Q9BVA1|TBB2B_HUMAN,sp|P07437|TBB5_HUMAN,sp|Q13885|TBB2A_HUMAN,sp|P68371|TBB4B_HUMAN,tr|Q5ST81|Q5ST81_HUMAN,tr|Q5JP53|Q5JP53_HUMAN,tr|M0QY85|M0QY85_HUMAN,tr|M0QZL7|M0QZL7_HUMAN,tr|M0R278|M0R278_HUMAN,tr|M0R1I1|M0R1I1_HUMAN" 11 2797.3361 0.73 56823 24892 3 2797.343697 933.4526 Tubulin beta-4A chain OS=Homo sapiens OX=9606 GN=TUBB4A PE=1 SV=2 8.46 3883.7 - 1.18E+06 - - - 2.7169 - 4.382 0.574 - 917.6 1 2 0 0.0076 26 0 0 0 3.28E+08 4.50E+08 - - - 8.3366 1 221125_WJC_METTL3_EV_vs_WT_F04.24893.24893.3 6.20E-10 20/84 K.TETGQELEC[160.03]LQDHLDDLVVEC[160.03]R[166.11].D "sp|Q92896|GSLG1_HUMAN,tr|H3BM42|H3BM42_HUMAN" 2 2668.1984 0.7 56824 24893 3 2668.200631 890.4067 Golgi apparatus protein 1 OS=Homo sapiens OX=9606 GN=GLG1 PE=1 SV=2 3.95 3883.9 - 799024 - - - 0.8301 - 4.587 0.644 - 451.8 1 2 0 0.0022 22 0 0 0 5.61E+06 7.99E+06 - - - 9.3307 1 221125_WJC_METTL3_EV_vs_WT_F04.24894.24894.3 3.45E-10 18/88 R.IITITGTQDQIQNAQYLLQNSVK.Q sp|P61978|HNRPK_HUMAN 1 2588.381 1.29 56825 24894 3 2588.384975 863.8009 Heterogeneous nuclear ribonucleoprotein K OS=Homo sapiens OX=9606 GN=HNRNPK PE=1 SV=1 5.83 3884 - 755138 - - - 1.5427 - 3.172 0.619 - 357.5 1 2 0 0.004 23 0 0 0 2.57E+07 1.99E+07 - - - 8.1482 0.9971 221125_WJC_METTL3_EV_vs_WT_F04.24895.24895.3 4.70E-10 21/92 K.GTAFVTLLNGEQAEAAINAFHQSR.L "sp|Q8IY67|RAVR1_HUMAN,tr|E9PAU2|E9PAU2_HUMAN,tr|A0A087WZ13|A0A087WZ13_HUMAN" 3 2544.2721 0.96 56826 24895 3 2545.264703 849.098 Ribonucleoprotein PTB-binding 1 OS=Homo sapiens OX=9606 GN=RAVER1 PE=1 SV=1 5.4 3884.1 - 748172 - - - 390.1324 - 3.904 0.597 - 496.5 1 2 0 0.9926 24 0 0 0 1.80E+07 1.88E+07 - - - 8.0844 1 221125_WJC_METTL3_EV_vs_WT_F04.24896.24896.3 6.75E-17 29/116 K.ENGTVTAANASTLNDGAAALVLMTADAAKR.L "sp|P24752|THIL_HUMAN,tr|A0A5F9ZHJ7|A0A5F9ZHJ7_HUMAN,tr|A0A5F9ZHD4|A0A5F9ZHD4_HUMAN,tr|A0A5F9ZHJ0|A0A5F9ZHJ0_HUMAN,tr|A0A5F9ZHL1|A0A5F9ZHL1_HUMAN,tr|A0A5F9ZI66|A0A5F9ZI66_HUMAN" 6 2916.4611 0.82 56827 24896 3 2916.465229 973.161 "Acetyl-CoA acetyltransferase, mitochondrial OS=Homo sapiens OX=9606 GN=ACAT1 PE=1 SV=1" 4.56 3884.3 - 587242 - - - 1.4161 - 4.967 0.779 - 740.3 1 2 0 0.0041 30 0 0 0 5.02E+06 6.10E+06 - - - 10.9114 1 221125_WJC_METTL3_EV_vs_WT_F04.24897.24897.3 1.66E-05 21/76 R.KAPPDGWELIEPTLDELDQK.M "sp|P41223|BUD31_HUMAN,tr|F8WCN7|F8WCN7_HUMAN,tr|C9JCD9|C9JCD9_HUMAN" 3 2293.1478 1.13 56828 24897 3 2293.153148 765.3899 Protein BUD31 homolog OS=Homo sapiens OX=9606 GN=BUD31 PE=1 SV=2 4.02 3884.4 - 576453 - - - 2.3348 - 3.939 0.509 - 602.7 1 2 0 0.0054 20 0 0 0 8.85E+06 7.86E+06 - - - 7.5393 1 221125_WJC_METTL3_EV_vs_WT_F04.24898.24898.3 2.66E-13 19/80 R.NQDETEDTELQGMNEYLSSFK.V "sp|Q14839|CHD4_HUMAN,tr|A0A2R8Y4X2|A0A2R8Y4X2_HUMAN,tr|A0A2U3TZM0|A0A2U3TZM0_HUMAN,tr|A0A2R8Y5M9|A0A2R8Y5M9_HUMAN,tr|A0A2R8Y685|A0A2R8Y685_HUMAN,tr|A0A2R8Y445|A0A2R8Y445_HUMAN,tr|A0A2R8YD40|A0A2R8YD40_HUMAN,tr|A0A2R8Y5J0|A0A2R8Y5J0_HUMAN,tr|A0A2R8Y425|A0A2R8Y425_HUMAN,tr|A0A2R8YFK9|A0A2R8YFK9_HUMAN,tr|A0A2R8Y8C1|A0A2R8Y8C1_HUMAN,tr|A0A0C4DGG9|A0A0C4DGG9_HUMAN,tr|A0A2R8YFD8|A0A2R8YFD8_HUMAN,tr|A0A2R8YDW2|A0A2R8YDW2_HUMAN,tr|A0A2R8Y5Z7|A0A2R8Y5Z7_HUMAN,tr|F5GWX5|F5GWX5_HUMAN,tr|A0A2R8YER1|A0A2R8YER1_HUMAN,tr|A0A2R8Y521|A0A2R8Y521_HUMAN,tr|A0A2R8YDJ9|A0A2R8YDJ9_HUMAN,tr|A0A2R8Y212|A0A2R8Y212_HUMAN,tr|A0A2R8YE38|A0A2R8YE38_HUMAN" 21 2477.054 0.62 56829 24898 3 2477.051597 826.692 Chromodomain-helicase-DNA-binding protein 4 OS=Homo sapiens OX=9606 GN=CHD4 PE=1 SV=2 3.77 3884.5 - 552411 - - - -0.9818 - 3.775 0.748 - 484.6 1 2 0 -0.0024 21 0 0 0 3.26E+06 5.29E+06 - - - 10.0636 0.9997 221125_WJC_METTL3_EV_vs_WT_F04.24900.24900.3 0.00148 Nov-56 R.SHQELISQLLQSYMK[136.11].L "sp|Q9Y2H2|SAC2_HUMAN,tr|A0A3B3ISI3|A0A3B3ISI3_HUMAN,tr|A0A3B3IRJ9|A0A3B3IRJ9_HUMAN,tr|A0A3B3ITL0|A0A3B3ITL0_HUMAN,tr|A0A3B3ITR9|A0A3B3ITR9_HUMAN" 5 1811.9331 0.26 56831 24900 3 1811.939333 604.985 Phosphatidylinositide phosphatase SAC2 OS=Homo sapiens OX=9606 GN=INPP5F PE=1 SV=3 6.47 3884.8 - 352198 - - - 3.4289 - 2.281 0.46 - 113.3 1 2 0 0.0062 15 0 0 0 1.07E+06 4.08E+06 - - - 5.8185 0.913 221125_WJC_METTL3_EV_vs_WT_F04.24903.24903.4 0.00084 8/114 V.GTRPINLEPIFQGYIDSLKR.Y sp|P35908|K22E_HUMAN 1 2316.259 999 56834 24903 4 2316.264417 580.072 "Keratin, type II cytoskeletal 2 epidermal OS=Homo sapiens OX=9606 GN=KRT2 PE=1 SV=2" 8.59 3885.2 - 156532 - - - 2.3318 - 1.743 0.35 - 29.7 1 1 0 0.0054 20 0 0 0 1.60E+06 0.00E+00 - - - 2.4567 1 221125_WJC_METTL3_EV_vs_WT_F04.24906.24906.3 3.41E-08 17/88 R.IITITGTQDQIQNAQYLLQNSVK[136.11].Q sp|P61978|HNRPK_HUMAN 1 2596.3952 1.29 56835 24906 3 2596.397784 866.4723 Heterogeneous nuclear ribonucleoprotein K OS=Homo sapiens OX=9606 GN=HNRNPK PE=1 SV=1 5.83 3885.6 - 2.26E+06 - - - 1.0022 - 3.162 0.567 - 302.4 1 2 0 0.0026 23 0 0 0 2.57E+07 1.99E+07 - - - 7.5614 0.9821 221125_WJC_METTL3_EV_vs_WT_F04.24907.24907.2 1.29E-05 24-Dec K.K[136.11]VSQEILELLNTT.T "sp|Q86U44|MTA70_HUMAN,tr|H0YFV6|H0YFV6_HUMAN" 2 1494.8385 0 56836 24907 2 1494.841334 748.4265 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 4.53 3885.7 - 694550 - - - 1.9133 - 2.528 0.435 - 593.2 1 1 0 0.0029 13 0 0 0 1.55E+05 7.14E+07 - - - 4.6333 0.9967 221125_WJC_METTL3_EV_vs_WT_F04.24910.24910.4 0.00317 11/168 K.MK[136.11]ETAENYLGHTAKNAVITVPAYFNDSQR.Q "sp|P38646|GRP75_HUMAN,tr|H0Y8K0|H0Y8K0_HUMAN,tr|A0A7I2V2S7|A0A7I2V2S7_HUMAN,tr|A0A7I2V2G2|A0A7I2V2G2_HUMAN,tr|A0A7I2V3F7|A0A7I2V3F7_HUMAN,tr|A0A7I2YQB2|A0A7I2YQB2_HUMAN,tr|D6RCD7|D6RCD7_HUMAN" 7 3275.6125 - 56839 24910 4 3275.616872 819.9104 "Stress-70 protein, mitochondrial OS=Homo sapiens OX=9606 GN=HSPA9 PE=1 SV=2" 6.51 3886.1 - 565582 - - - 1.3466 - 2.469 0.305 - 29.6 1 2 2 0.0044 29 0 0 0 - - - - - 2.158 0.9975 221125_WJC_METTL3_EV_vs_WT_F04.24911.24911.4 0.000125 17/108 G.TRPINLEPIFQGYIDSLKR.Y sp|P35908|K22E_HUMAN 1 2259.2376 999 56840 24911 4 2259.240024 565.8167 "Keratin, type II cytoskeletal 2 epidermal OS=Homo sapiens OX=9606 GN=KRT2 PE=1 SV=2" 8.25 3886.2 - 372132 - - - 1.0942 - 3.5 0.546 - 207.3 1 1 0 0.0025 19 0 0 0 8.66E+06 0.00E+00 - - - 4.4015 0.9995 221125_WJC_METTL3_EV_vs_WT_F04.24912.24912.3 0.000922 Nov-72 R.ENK[136.11]PSIIFIDEIDSLC[160.03]GSR[166.11].S sp|O75351|VPS4B_HUMAN 1 2210.1008 0.18 56841 24912 3 2210.09908 737.7075 Vacuolar protein sorting-associated protein 4B OS=Homo sapiens OX=9606 GN=VPS4B PE=1 SV=2 4.32 3886.4 - 368960 - - - -0.7801 - 2.195 0.301 - 142.6 1 2 0 -0.0017 19 0 0 0 1.38E+06 7.70E+06 - - - 3.8269 0.9999 221125_WJC_METTL3_EV_vs_WT_F04.24913.24913.3 1.22E-09 11/120 K.ESDTGLAPPALWDLAADK[136.11]QTLQSEQPLQVAR[166.11].C "sp|P35998|PRS7_HUMAN,tr|C9JX88|C9JX88_HUMAN,tr|C9JLS9|C9JLS9_HUMAN" 3 3365.7222 0.54 56842 24913 3 3365.72792 1122.9147 26S proteasome regulatory subunit 7 OS=Homo sapiens OX=9606 GN=PSMC2 PE=1 SV=3 4.11 3886.5 - 336310 - - - 1.6935 - 2.726 0.566 - 30.2 1 2 1 0.0057 31 0 0 0 2.09E+06 3.86E+06 - - - 7.1559 1 221125_WJC_METTL3_EV_vs_WT_F04.24918.24918.3 6.92E-10 24/96 K.DGDVTVTNDGATILSMMDVDHQIAK[136.11].L "sp|P48643|TCPE_HUMAN,tr|E9PCA1|E9PCA1_HUMAN,tr|B7ZAR1|B7ZAR1_HUMAN" 3 2653.2455 0.47 56845 24918 3 2653.247463 885.4224 T-complex protein 1 subunit epsilon OS=Homo sapiens OX=9606 GN=CCT5 PE=1 SV=1 3.97 3887.1 - 2.98E+06 - - - 0.7466 - 4.126 0.67 - 384.2 1 2 0 0.002 25 0 0 0 2.27E+07 4.86E+07 - - - 9.27 0.9999 221125_WJC_METTL3_EV_vs_WT_F04.24921.24921.3 2.05E-11 18/104 K.NFQNIFPPSATLHLSNIPPSVSEEDLK.V "sp|P26599|PTBP1_HUMAN,tr|A0A0U1RRM4|A0A0U1RRM4_HUMAN,tr|A6NLN1|A6NLN1_HUMAN,tr|A0A0D9SF20|A0A0D9SF20_HUMAN,tr|A0A7I2V621|A0A7I2V621_HUMAN" 5 2993.5135 1.44 56848 24921 3 2993.526129 998.8451 Polypyrimidine tract-binding protein 1 OS=Homo sapiens OX=9606 GN=PTBP1 PE=1 SV=1 4.65 3887.5 - 402984 - - - 4.2348 - 3.483 0.623 - 201.1 1 2 0 0.0127 27 0 0 0 6.80E+06 4.72E+06 - - - 8.3533 0.997 221125_WJC_METTL3_EV_vs_WT_F04.24922.24922.4 4.59E-07 16/150 R.SGPFGQIFRPDNFVFGQSGAGNNWAK.G "sp|P04350|TBB4A_HUMAN,sp|Q9BVA1|TBB2B_HUMAN,sp|P07437|TBB5_HUMAN,sp|Q13885|TBB2A_HUMAN,sp|P68371|TBB4B_HUMAN,tr|Q5ST81|Q5ST81_HUMAN,tr|Q5JP53|Q5JP53_HUMAN,tr|M0QY85|M0QY85_HUMAN,tr|M0QZL7|M0QZL7_HUMAN,tr|M0R278|M0R278_HUMAN,tr|M0R1I1|M0R1I1_HUMAN" 11 2797.3361 0.57 56849 24922 4 2798.344924 700.3413 Tubulin beta-4A chain OS=Homo sapiens OX=9606 GN=TUBB4A PE=1 SV=2 8.46 3887.6 - 143420 - - - 360.6385 - 2.557 0.491 - 139.5 1 2 0 1.0088 26 0 0 0 1.19E+07 2.07E+07 - - - 3.5164 0.9998 221125_WJC_METTL3_EV_vs_WT_F04.24926.24926.3 2.54E-05 14/68 R.DR[166.11]VTSAVEALLSADSASR[166.11].K sp|P45974|UBP5_HUMAN 1 1866.955 1.15 56851 24926 3 1866.956164 623.3256 Ubiquitin carboxyl-terminal hydrolase 5 OS=Homo sapiens OX=9606 GN=USP5 PE=1 SV=2 4.56 3888.2 - 459570 - - - 0.6187 - 2.942 0.463 - 285.3 1 2 1 0.0012 18 0 0 0 5.46E+06 4.74E+06 - - - 6.3887 1 221125_WJC_METTL3_EV_vs_WT_F04.24932.24932.3 2.69E-12 19/88 K.LNNDDNVDGLLVQLPLPEHIDER.R "sp|P13995|MTDC_HUMAN,tr|A0A7I2V482|A0A7I2V482_HUMAN,tr|A0A7I2V2U6|A0A7I2V2U6_HUMAN,tr|A0A7I2YQD4|A0A7I2YQD4_HUMAN" 4 2627.3191 1.26 56856 24932 3 2627.317373 876.7803 "Bifunctional methylenetetrahydrofolate dehydrogenase\cyclohydrolase, mitochondrial OS=Homo sapiens OX=9606 GN=MTHFD2 PE=1 SV=2" 3.96 3888.9 - 479667 - - - -0.6611 - 3.801 0.584 - 243.8 1 2 0 -0.0017 23 0 0 0 9.89E+07 7.88E+07 - - - 8.183 0.9999 221125_WJC_METTL3_EV_vs_WT_F04.24935.24935.3 0.000213 13/68 R.DRVTSAVEALLSADSASR.K sp|P45974|UBP5_HUMAN 1 1846.9385 0.93 56858 24935 3 1846.939208 616.6534 Ubiquitin carboxyl-terminal hydrolase 5 OS=Homo sapiens OX=9606 GN=USP5 PE=1 SV=2 4.56 3889.2 - 503738 - - - 0.4001 - 2.754 0.486 - 196.4 1 2 1 0.0007 18 0 0 0 5.46E+06 5.89E+06 - - - 6.4808 1 221125_WJC_METTL3_EV_vs_WT_F04.24938.24938.4 3.98E-09 20/120 R.QVLDLEDLVFTQGSHFMANKR.C "sp|O75643|U520_HUMAN,tr|A0A494C1A5|A0A494C1A5_HUMAN" 2 2447.2267 1.07 56861 24938 4 2447.228491 612.814 U5 small nuclear ribonucleoprotein 200 kDa helicase OS=Homo sapiens OX=9606 GN=SNRNP200 PE=1 SV=2 5.38 3889.6 - 346870 - - - 0.72 - 3.787 0.589 - 170.1 1 2 0 0.0018 21 0 0 0 2.78E+07 2.61E+07 - - - 4.7924 0.9927 221125_WJC_METTL3_EV_vs_WT_F04.24947.24947.3 0.00215 Oct-76 K.GNPQGFNQGLDC[160.03]DVIVAEVR[166.11].S sp|Q86U44|MTA70_HUMAN 1 2197.0461 0.07 56868 24947 3 2198.047677 733.356 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 4.03 3890.8 - 223692 - - - 455.858 - 2.188 0.372 - 112.9 1 2 0 1.0015 20 0 0 0 1.62E+05 2.22E+06 - - - 4.3096 0.9991 221125_WJC_METTL3_EV_vs_WT_F04.24954.24954.2 0.0456 16-Aug R.IDLAVLLGK.T "sp|Q14157|UBP2L_HUMAN,tr|F8W726|F8W726_HUMAN,tr|Q5VU77|Q5VU77_HUMAN" 3 940.5957 1.96 56873 24954 2 940.596579 471.3051 Ubiquitin-associated protein 2-like OS=Homo sapiens OX=9606 GN=UBAP2L PE=1 SV=2 5.84 3891.7 - 117181 - - - 0.9154 - 1.656 0.29 - 147.9 1 2 0 0.0009 9 0 0 0 1.20E+06 6.12E+05 - - - 2.6419 0.9999 221125_WJC_METTL3_EV_vs_WT_F04.24957.24957.3 5.02E-08 19/72 R.ADLEMQIESLKEELAYLKK.N sp|P02533|K1C14_HUMAN 1 2250.1817 999 56874 24957 3 2250.184278 751.0679 "Keratin, type I cytoskeletal 14 OS=Homo sapiens OX=9606 GN=KRT14 PE=1 SV=4" 4.59 3892.1 - 1.37E+06 - - - 1.1297 - 3.894 0.558 - 537.9 1 2 1 0.0025 19 0 0 0 4.75E+07 0.00E+00 - - - 8.1003 1 221125_WJC_METTL3_EV_vs_WT_F04.24960.24960.4 1.29E-06 11/138 K.HAAWYPSEILDPHVVLLTSDNVIR[166.11].L "sp|Q99567|NUP88_HUMAN,tr|J3KMX1|J3KMX1_HUMAN,tr|I3L245|I3L245_HUMAN" 3 2754.4369 1.64 56877 24960 4 2754.440982 689.6165 Nuclear pore complex protein Nup88 OS=Homo sapiens OX=9606 GN=NUP88 PE=1 SV=2 5.21 3892.5 - 267243 - - - 1.4929 - 2.668 0.511 - 66.4 1 2 0 0.0041 24 0 0 0 3.87E+06 2.35E+06 - - - 3.9876 1 221125_WJC_METTL3_EV_vs_WT_F04.24967.24967.3 7.26E-17 27/112 R.HGLANLTAELLQQGANPNLQTEEALPLPK.E sp|Q9P2R3|ANFY1_HUMAN 1 3079.6302 1.86 56882 24967 3 3079.634464 1027.5507 Rabankyrin-5 OS=Homo sapiens OX=9606 GN=ANKFY1 PE=1 SV=2 4.75 3893.4 - 544484 - - - 1.3804 - 5.091 0.737 - 691.7 1 2 0 0.0043 29 0 0 0 4.58E+06 2.46E+06 - - - 10.4999 0.9996 221125_WJC_METTL3_EV_vs_WT_F04.24968.24968.3 0.0915 Nov-92 R.ENPDLAC[160.03]LQSIIFDEER[166.11]SPEEQAK[136.11].T sp|O95801|TTC4_HUMAN 1 2835.3352 0.001 56883 24968 3 2835.329921 946.119 Tetratricopeptide repeat protein 4 OS=Homo sapiens OX=9606 GN=TTC4 PE=1 SV=3 4 3893.5 - 375251 - - - -1.8527 - 2.908 0.435 - 62.1 1 2 1 -0.0053 24 0 0 0 0.00E+00 5.86E+06 - - - 5.8677 1 221125_WJC_METTL3_EV_vs_WT_F04.24970.24970.4 1.08E-12 20/138 K.HAAWYPSEILDPHVVLLTSDNVIR.L "sp|Q99567|NUP88_HUMAN,tr|J3KMX1|J3KMX1_HUMAN,tr|I3L245|I3L245_HUMAN" 3 2744.4286 1.69 56885 24970 4 2744.436874 687.1144 Nuclear pore complex protein Nup88 OS=Homo sapiens OX=9606 GN=NUP88 PE=1 SV=2 5.21 3893.8 - 365072 - - - 3.0148 - 3.628 0.645 - 253.8 1 2 0 0.0083 24 0 0 0 3.87E+06 2.29E+06 - - - 5.2514 0.9999 221125_WJC_METTL3_EV_vs_WT_F04.24976.24976.3 0.000302 7/152 K.SGLVGGQLSGGLGLPPGK[136.11]PPSSSPLTGASPPSFLQGLC[160.03]R[166.11].D sp|Q9H7S9|ZN703_HUMAN 1 3747.9737 2.68 56891 24976 3 3747.973493 1250.3318 Zinc finger protein 703 OS=Homo sapiens OX=9606 GN=ZNF703 PE=1 SV=1 9.5 3894.5 - 161292 - - - -0.0552 - 1.633 0.469 - 16.2 1 2 0 -0.0002 39 0 0 0 2.59E+06 9.69E+05 - - - 4.8971 1 221125_WJC_METTL3_EV_vs_WT_F04.24980.24980.4 3.33E-12 23/144 R.R[166.11]PVINAGDGVGEHPTQALLDIFTIR[166.11].E "sp|P27708|PYR1_HUMAN,tr|F8VPD4|F8VPD4_HUMAN,tr|H7C2E4|H7C2E4_HUMAN" 3 2708.4513 0.37 56893 24980 4 2708.449249 678.1201 CAD protein OS=Homo sapiens OX=9606 GN=CAD PE=1 SV=3 5.38 3895.1 - 590405 - - - -0.7528 - 3.813 0.669 - 388.5 1 2 0 -0.002 25 0 0 0 2.86E+06 7.82E+06 - - - 5.4742 0.9999 221125_WJC_METTL3_EV_vs_WT_F04.24982.24982.4 7.01E-08 29/126 R.TLQEDLVKDVLSNAHIQNELER.E "sp|P24928|RPB1_HUMAN,tr|A0A6Q8PGB0|A0A6Q8PGB0_HUMAN" 2 2563.3242 1.73 56895 24982 4 2563.324152 641.8383 DNA-directed RNA polymerase II subunit RPB1 OS=Homo sapiens OX=9606 GN=POLR2A PE=1 SV=2 4.5 3895.3 - 1.33E+06 - - - -0.0168 - 4.717 0.57 - 398.3 1 2 1 0 22 0 0 0 1.01E+07 5.84E+06 - - - 4.6948 1 221125_WJC_METTL3_EV_vs_WT_F04.24983.24983.4 5.21E-08 23/150 R.SGPFGQIFR[166.11]PDNFVFGQSGAGNNWAK[136.11].G "sp|P04350|TBB4A_HUMAN,sp|Q9BVA1|TBB2B_HUMAN,sp|P07437|TBB5_HUMAN,sp|Q13885|TBB2A_HUMAN,sp|P68371|TBB4B_HUMAN,tr|Q5ST81|Q5ST81_HUMAN,tr|Q5JP53|Q5JP53_HUMAN,tr|M0QY85|M0QY85_HUMAN,tr|M0QZL7|M0QZL7_HUMAN,tr|M0R278|M0R278_HUMAN,tr|M0R1I1|M0R1I1_HUMAN" 11 2815.3586 0.65 56896 24983 4 2815.357811 704.8469 Tubulin beta-4A chain OS=Homo sapiens OX=9606 GN=TUBB4A PE=1 SV=2 8.46 3895.4 - 1.30E+06 - - - -0.2685 - 3.853 0.537 - 327.4 1 2 0 -0.0008 26 0 0 0 1.44E+07 2.24E+07 - - - 4.3253 1 221125_WJC_METTL3_EV_vs_WT_F04.24986.24986.2 4.64E-08 14/30 K.K[136.11]VSQEILELLNTTTAK[136.11].E "sp|Q86U44|MTA70_HUMAN,tr|H0YFV6|H0YFV6_HUMAN" 2 1803.0324 0.001 56899 24986 2 1803.029427 902.5235 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 6.14 3895.8 - 301003 - - - -1.6655 - 3.201 0.637 - 533.7 1 2 0 -0.003 16 0 0 0 0.00E+00 1.55E+07 - - - 6.6054 1 221125_WJC_METTL3_EV_vs_WT_F04.24989.24989.4 5.72E-12 21/108 R.ADLEMQIESLKEELAYLKK.N sp|P02533|K1C14_HUMAN 1 2250.1817 999 56901 24989 4 2250.1833 563.5527 "Keratin, type I cytoskeletal 14 OS=Homo sapiens OX=9606 GN=KRT14 PE=1 SV=4" 4.59 3896.2 - 4.39E+07 - - - 0.6951 - 4.323 0.649 - 498.5 1 2 1 0.0016 19 0 0 0 1.90E+08 0.00E+00 - - - 5.3697 1 221125_WJC_METTL3_EV_vs_WT_F04.24992.24992.3 1.28E-10 18/84 K.EK[136.11]PYFPIPEEYTFIQNVPLEDR[166.11].V "sp|Q00839|HNRPU_HUMAN,tr|A0A1W2PQL0|A0A1W2PQL0_HUMAN,tr|A0A1W2PPL4|A0A1W2PPL4_HUMAN,tr|A0A1W2PQ74|A0A1W2PQ74_HUMAN,tr|Q5RI18|Q5RI18_HUMAN,tr|A0A1W2PP35|A0A1W2PP35_HUMAN,tr|A0A1W2PPS1|A0A1W2PPS1_HUMAN,tr|A0A1W2PRZ7|A0A1W2PRZ7_HUMAN,tr|A0A1W2PPH7|A0A1W2PPH7_HUMAN,tr|A0A1W2PP34|A0A1W2PP34_HUMAN,tr|A0A1X7SBS1|A0A1X7SBS1_HUMAN" 11 2741.3708 1.19 56903 24992 3 2741.367525 914.7975 Heterogeneous nuclear ribonucleoprotein U OS=Homo sapiens OX=9606 GN=HNRNPU PE=1 SV=6 4.25 3896.5 - 1.13E+06 - - - -1.1779 - 3.527 0.651 - 233.3 1 2 0 -0.0032 22 0 0 0 3.17E+08 2.66E+08 - - - 8.7854 1 221125_WJC_METTL3_EV_vs_WT_F04.24995.24995.3 3.16E-11 18/88 R.NEDEDSPNKLYTLVTYVPVTTFK.N "sp|P62899|RL31_HUMAN,tr|B7Z4C8|B7Z4C8_HUMAN,tr|B7Z4E3|B7Z4E3_HUMAN,tr|H7C2W9|H7C2W9_HUMAN,tr|C9JU56|C9JU56_HUMAN" 5 2672.3221 1.5 56906 24995 3 2672.32108 891.7813 60S ribosomal protein L31 OS=Homo sapiens OX=9606 GN=RPL31 PE=1 SV=1 4.32 3896.9 - 345025 - - - -0.3925 - 3.428 0.649 - 230.6 1 2 1 -0.001 23 0 0 0 2.64E+07 1.77E+07 - - - 8.6656 0.9999 221125_WJC_METTL3_EV_vs_WT_F04.24996.24996.4 3.51E-08 16/102 R.SIQAALDSAYK[136.11]ELTDLHK[136.11].A "sp|P82094|TMF1_HUMAN,tr|F8WF45|F8WF45_HUMAN" 2 2018.0655 1.49 56907 24996 4 2018.063559 505.5237 TATA element modulatory factor OS=Homo sapiens OX=9606 GN=TMF1 PE=1 SV=2 5.36 3897.1 - 343921 - - - -0.9722 - 2.738 0.552 - 107.5 1 2 1 -0.002 18 0 0 0 9.11E+06 6.09E+06 - - - 4.3751 0.9999 221125_WJC_METTL3_EV_vs_WT_F04.25001.25001.4 8.70E-07 19/102 R.SIQAALDSAYKELTDLHK.A "sp|P82094|TMF1_HUMAN,tr|F8WF45|F8WF45_HUMAN" 2 2002.0371 1.49 56910 25001 4 2002.03723 501.5166 TATA element modulatory factor OS=Homo sapiens OX=9606 GN=TMF1 PE=1 SV=2 5.36 3897.7 - 541489 - - - 0.0544 - 3.953 0.609 - 196.8 1 2 1 0.0001 18 0 0 0 9.11E+06 6.09E+06 - - - 4.9975 0.9891 221125_WJC_METTL3_EV_vs_WT_F04.25004.25004.3 1.25E-06 13/76 Y.YNTIDDLKDQIVDLTVGNNK.T sp|P35527|K1C9_HUMAN 1 2277.1489 1.51 56911 25004 3 2277.15011 760.0569 "Keratin, type I cytoskeletal 9 OS=Homo sapiens OX=9606 GN=KRT9 PE=1 SV=3" 4.14 3898.1 - 633900 - - - 0.5507 - 2.868 0.518 - 160.2 1 1 1 0.0013 20 0 0 0 1.29E+08 8.54E+07 - - - 6.8709 1 221125_WJC_METTL3_EV_vs_WT_F04.25005.25005.3 3.25E-11 19/88 R.NEDEDSPNK[136.11]LYTLVTYVPVTTFK[136.11].N "sp|P62899|RL31_HUMAN,tr|B7Z4C8|B7Z4C8_HUMAN,tr|B7Z4E3|B7Z4E3_HUMAN,tr|H7C2W9|H7C2W9_HUMAN,tr|C9JU56|C9JU56_HUMAN" 5 2688.3505 1.5 56912 25005 3 2688.347756 897.1241 60S ribosomal protein L31 OS=Homo sapiens OX=9606 GN=RPL31 PE=1 SV=1 4.32 3898.2 - 778669 - - - -1.0315 - 3.462 0.683 - 260.1 1 2 1 -0.0028 23 0 0 0 2.64E+07 1.77E+07 - - - 9.0673 1 221125_WJC_METTL3_EV_vs_WT_F04.25013.25013.3 1.56E-06 13/104 K.NFQNIFPPSATLHLSNIPPSVSEEDLK[136.11].V "sp|P26599|PTBP1_HUMAN,tr|A0A0U1RRM4|A0A0U1RRM4_HUMAN,tr|A6NLN1|A6NLN1_HUMAN,tr|A0A0D9SF20|A0A0D9SF20_HUMAN,tr|A0A7I2V621|A0A7I2V621_HUMAN" 5 3001.5277 1.41 56918 25013 3 3001.529557 1001.5165 Polypyrimidine tract-binding protein 1 OS=Homo sapiens OX=9606 GN=PTBP1 PE=1 SV=1 4.65 3899.3 - 520122 - - - 0.6347 - 2.519 0.534 - 94.7 1 2 0 0.0019 27 0 0 0 1.95E+07 1.38E+07 - - - 6.6185 0.9999 221125_WJC_METTL3_EV_vs_WT_F04.25025.25025.3 1.96E-05 Nov-56 K.EISLWFK[136.11]PEELVDYK[136.11].S "sp|P22392|NDKB_HUMAN,tr|Q32Q12|Q32Q12_HUMAN" 2 1911.0001 1.72 56926 25025 3 1910.999975 638.0073 Nucleoside diphosphate kinase B OS=Homo sapiens OX=9606 GN=NME2 PE=1 SV=1 4.41 3900.9 - 322315 - - - -0.0481 - 2.335 0.435 - 137.7 1 2 0 -0.0001 15 0 0 0 9.17E+06 5.34E+06 - - - 5.6026 0.9999 221125_WJC_METTL3_EV_vs_WT_F04.25026.25026.4 5.32E-07 20/126 R.EK[136.11]LEAYQHLFYLLQTNPTYLAK[136.11].L "sp|P46940|IQGA1_HUMAN,tr|H0YLE8|H0YLE8_HUMAN,tr|A0A0J9YXZ5|A0A0J9YXZ5_HUMAN" 3 2698.4341 0.81 56927 25026 4 2698.431236 675.6158 Ras GTPase-activating-like protein IQGAP1 OS=Homo sapiens OX=9606 GN=IQGAP1 PE=1 SV=1 6.85 3901 - 313105 - - - -1.0762 - 4.047 0.539 - 267.2 1 2 1 -0.0029 22 0 0 0 9.66E+06 1.19E+07 - - - 4.3741 0.9999 221125_WJC_METTL3_EV_vs_WT_F04.25030.25030.3 8.05E-08 14/64 K.MEIDLKDLEAQIEAANK.A sp|P35580|MYH10_HUMAN 1 1929.9717 0.39 56928 25030 3 1929.971619 644.3312 Myosin-10 OS=Homo sapiens OX=9606 GN=MYH10 PE=1 SV=3 4.18 3901.6 - 396050 - - - -0.0642 - 2.867 0.554 - 260 1 2 1 -0.0001 17 0 0 0 1.17E+07 3.02E+07 - - - 7.3774 0.9999 221125_WJC_METTL3_EV_vs_WT_F04.25032.25032.4 1.22E-09 21/126 R.EKLEAYQHLFYLLQTNPTYLAK.L "sp|P46940|IQGA1_HUMAN,tr|H0YLE8|H0YLE8_HUMAN,tr|A0A0J9YXZ5|A0A0J9YXZ5_HUMAN" 3 2682.4057 0.81 56930 25032 4 2682.400291 671.6087 Ras GTPase-activating-like protein IQGAP1 OS=Homo sapiens OX=9606 GN=IQGAP1 PE=1 SV=1 6.85 3901.9 - 771805 - - - -2.0314 - 4.102 0.564 - 308.2 1 2 1 -0.0054 22 0 0 0 9.61E+06 1.19E+07 - - - 4.5954 0.9998 221125_WJC_METTL3_EV_vs_WT_F04.25036.25036.3 0.000528 16/60 R.SLVEIIEHGLVDEQQK.V sp|O75533|SF3B1_HUMAN 1 1835.9629 1.75 56932 25036 3 1835.966093 612.9949 Splicing factor 3B subunit 1 OS=Homo sapiens OX=9606 GN=SF3B1 PE=1 SV=3 4.4 3902.4 - 224992 - - - 1.743 - 2.342 0.392 - 222.3 1 2 0 0.0032 16 0 0 0 5.54E+06 3.17E+06 - - - 5.0931 0.9947 221125_WJC_METTL3_EV_vs_WT_F04.25037.25037.2 0.0396 14-Jun R.GFGFVLFK[136.11].E "sp|Q14103|HNRPD_HUMAN,sp|O14979|HNRDL_HUMAN,tr|H0Y8G5|H0Y8G5_HUMAN,tr|A0A087WUK2|A0A087WUK2_HUMAN,tr|D6RF44|D6RF44_HUMAN,tr|D6RBQ9|D6RBQ9_HUMAN,tr|D6RAF8|D6RAF8_HUMAN,tr|H0YA96|H0YA96_HUMAN" 8 921.5204 1.21 56933 25037 2 921.518406 461.7675 Heterogeneous nuclear ribonucleoprotein D0 OS=Homo sapiens OX=9606 GN=HNRNPD PE=1 SV=1 8.75 3902.5 - 188061 - - - -2.1367 - 0.988 0.366 - 109.6 1 2 0 -0.002 8 0 0 0 4.57E+06 3.79E+06 - - - 1.7072 0.9944 221125_WJC_METTL3_EV_vs_WT_F04.25038.25038.2 1.36E-06 14/26 K.K[136.11]VSQEILELLNTTT.A "sp|Q86U44|MTA70_HUMAN,tr|H0YFV6|H0YFV6_HUMAN" 2 1595.8862 0.001 56934 25038 2 1595.886731 798.9504 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 4.53 3902.6 - 916101 - - - 0.3622 - 2.703 0.536 - 821.7 1 1 0 0.0006 14 0 0 0 0.00E+00 2.53E+07 - - - 5.495 1 221125_WJC_METTL3_EV_vs_WT_F04.25041.25041.3 3.46E-12 20/84 K.EKPYFPIPEEYTFIQNVPLEDR.V "sp|Q00839|HNRPU_HUMAN,tr|A0A1W2PQL0|A0A1W2PQL0_HUMAN,tr|A0A1W2PPL4|A0A1W2PPL4_HUMAN,tr|A0A1W2PQ74|A0A1W2PQ74_HUMAN,tr|Q5RI18|Q5RI18_HUMAN,tr|A0A1W2PP35|A0A1W2PP35_HUMAN,tr|A0A1W2PPS1|A0A1W2PPS1_HUMAN,tr|A0A1W2PRZ7|A0A1W2PRZ7_HUMAN,tr|A0A1W2PPH7|A0A1W2PPH7_HUMAN,tr|A0A1W2PP34|A0A1W2PP34_HUMAN,tr|A0A1X7SBS1|A0A1X7SBS1_HUMAN" 11 2723.3483 1.19 56935 25041 3 2723.345614 908.79 Heterogeneous nuclear ribonucleoprotein U OS=Homo sapiens OX=9606 GN=HNRNPU PE=1 SV=6 4.25 3903 - 1.52E+07 - - - -0.9804 - 3.774 0.684 - 295.8 1 2 0 -0.0027 22 0 0 0 3.17E+08 2.66E+08 - - - 9.314 0.9999 221125_WJC_METTL3_EV_vs_WT_F04.25045.25045.3 5.50E-05 13/68 K.EAQTSFLHLGYLPNQLFR[166.11].T "sp|Q92499|DDX1_HUMAN,tr|A0A7I2V2M5|A0A7I2V2M5_HUMAN,tr|A0A087X2G1|A0A087X2G1_HUMAN,tr|A0A7I2V430|A0A7I2V430_HUMAN,tr|A0A7I2V4F0|A0A7I2V4F0_HUMAN,tr|A0A087WZ71|A0A087WZ71_HUMAN,tr|A0A7I2YQ77|A0A7I2YQ77_HUMAN" 7 2143.109 1.06 56939 25045 3 2143.110956 715.3769 ATP-dependent RNA helicase DDX1 OS=Homo sapiens OX=9606 GN=DDX1 PE=1 SV=2 6.85 3903.4 - 337936 - - - 0.9155 - 2.325 0.391 - 158.5 1 2 0 0.002 18 0 0 0 7.25E+06 6.82E+06 - - - 4.9997 0.9974 221125_WJC_METTL3_EV_vs_WT_F04.25049.25049.4 1.40E-08 25/126 M.NVGTRPINLEPIFQGYIDSLKR.Y sp|P35908|K22E_HUMAN 1 2529.3704 111.42 56941 25049 4 2529.370881 633.3499 "Keratin, type II cytoskeletal 2 epidermal OS=Homo sapiens OX=9606 GN=KRT2 PE=1 SV=2" 8.59 3903.9 - 2.24E+06 - - - 0.2072 - 4.268 0.534 - 357.4 1 1 0 0.0005 22 0 0 0 2.04E+08 1.83E+06 - - - 4.3486 1 221125_WJC_METTL3_EV_vs_WT_F04.25051.25051.3 2.05E-11 25/92 K.ETVYC[160.03]LNDDDETEVLKEDIIQGFR.Y sp|P13010|XRCC5_HUMAN 1 2900.3386 1.77 56942 25051 3 2900.330285 967.7868 X-ray repair cross-complementing protein 5 OS=Homo sapiens OX=9606 GN=XRCC5 PE=1 SV=3 3.85 3904.1 - 590517 - - - -2.8614 - 5.112 0.773 - 746.5 1 2 1 -0.0083 24 0 0 0 2.89E+07 1.63E+07 - - - 10.9454 0.9999 221125_WJC_METTL3_EV_vs_WT_F04.25052.25052.3 2.90E-06 17/68 K.EAQTSFLHLGYLPNQLFR.T "sp|Q92499|DDX1_HUMAN,tr|A0A7I2V2M5|A0A7I2V2M5_HUMAN,tr|A0A087X2G1|A0A087X2G1_HUMAN,tr|A0A7I2V430|A0A7I2V430_HUMAN,tr|A0A7I2V4F0|A0A7I2V4F0_HUMAN,tr|A0A087WZ71|A0A087WZ71_HUMAN,tr|A0A7I2YQ77|A0A7I2YQ77_HUMAN" 7 2133.1007 1.06 56943 25052 3 2133.104433 712.0409 ATP-dependent RNA helicase DDX1 OS=Homo sapiens OX=9606 GN=DDX1 PE=1 SV=2 6.85 3904.3 - 258850 - - - 1.7388 - 2.68 0.472 - 319.5 1 2 0 0.0037 18 0 0 0 7.25E+06 6.82E+06 - - - 6.2561 1 221125_WJC_METTL3_EV_vs_WT_F04.25058.25058.3 2.40E-10 22/120 R.GNDETIGFEDILNDPSQSEVMGEPHLMVEYK.L "sp|Q9Y244|POMP_HUMAN,tr|A0A1W2PS02|A0A1W2PS02_HUMAN" 2 3492.5701 2.95 56946 25058 3 3492.565381 1165.1973 Proteasome maturation protein OS=Homo sapiens OX=9606 GN=POMP PE=1 SV=1 3.89 3905 - 1.01E+06 - - - -1.356 - 4.586 0.705 - 330.2 1 2 0 -0.0047 31 0 0 0 1.12E+07 3.80E+06 - - - 9.9026 0.9999 221125_WJC_METTL3_EV_vs_WT_F04.25059.25059.4 5.98E-07 21/144 R.VFTTQELVQAFTHAPATLEADRGGK.F "sp|O95433|AHSA1_HUMAN,tr|H0YJ63|H0YJ63_HUMAN,tr|G3V438|G3V438_HUMAN,tr|H0YJG7|H0YJG7_HUMAN" 4 2686.3715 1.48 56947 25059 4 2686.370486 672.6001 Activator of 90 kDa heat shock protein ATPase homolog 1 OS=Homo sapiens OX=9606 GN=AHSA1 PE=1 SV=1 5.44 3905.1 - 474575 - - - -0.3696 - 4.115 0.547 - 181.4 1 2 1 -0.001 25 0 0 0 9.96E+06 6.72E+06 - - - 4.4368 0.9995 221125_WJC_METTL3_EV_vs_WT_F04.25066.25066.3 2.02E-12 25/84 R.QLLAQQLGAESADSIGAVLNSK[136.11].D "sp|Q9HCE5|MET14_HUMAN,tr|A0A0D9SFW0|A0A0D9SFW0_HUMAN,tr|A0A0D9SF88|A0A0D9SF88_HUMAN" 3 2220.1841 0.03 56950 25066 3 2221.183331 741.0687 N6-adenosine-methyltransferase non-catalytic subunit OS=Homo sapiens OX=9606 GN=METTL14 PE=1 SV=2 4.37 3906.1 - 735496 - - - 450.055 - 4.434 0.59 - 800.5 1 2 0 0.9992 22 0 0 0 2.60E+05 9.90E+06 - - - 8.372 1 221125_WJC_METTL3_EV_vs_WT_F04.25069.25069.3 3.33E-11 18/124 R.C[160.03]SEGSFLLTTFPRPVTVEPMDQLDDEEGLPEK.L "sp|Q15233|NONO_HUMAN,tr|A0A7I2V535|A0A7I2V535_HUMAN,tr|A0A7I2V4N2|A0A7I2V4N2_HUMAN,tr|A0A7I2V464|A0A7I2V464_HUMAN,tr|A0A7P0MRW0|A0A7P0MRW0_HUMAN,tr|H7C367|H7C367_HUMAN,tr|A0A7I2V4J2|A0A7I2V4J2_HUMAN,tr|A0A7I2V5Y7|A0A7I2V5Y7_HUMAN" 8 3635.7011 0.43 56953 25069 3 3635.697689 1212.9077 Non-POU domain-containing octamer-binding protein OS=Homo sapiens OX=9606 GN=NONO PE=1 SV=4 3.89 3906.5 - 286302 - - - -0.947 - 3.34 0.654 - 173.3 1 2 0 -0.0034 32 0 0 0 3.73E+06 8.76E+06 - - - 8.605 1 221125_WJC_METTL3_EV_vs_WT_F04.25074.25074.3 9.04E-09 18/124 R.C[160.03]SEGSFLLTTFPR[166.11]PVTVEPMDQLDDEEGLPEK[136.11].L "sp|Q15233|NONO_HUMAN,tr|A0A7I2V535|A0A7I2V535_HUMAN,tr|A0A7I2V4N2|A0A7I2V4N2_HUMAN,tr|A0A7I2V464|A0A7I2V464_HUMAN,tr|A0A7P0MRW0|A0A7P0MRW0_HUMAN,tr|H7C367|H7C367_HUMAN,tr|A0A7I2V4J2|A0A7I2V4J2_HUMAN,tr|A0A7I2V5Y7|A0A7I2V5Y7_HUMAN" 8 3653.7236 0.43 56956 25074 3 3653.730695 1218.9151 Non-POU domain-containing octamer-binding protein OS=Homo sapiens OX=9606 GN=NONO PE=1 SV=4 3.89 3907.1 - 571502 - - - 1.9413 - 2.776 0.618 - 162.8 1 2 0 0.0071 32 0 0 0 3.73E+06 8.76E+06 - - - 7.7771 1 221125_WJC_METTL3_EV_vs_WT_F04.25075.25075.4 1.02E-09 18/96 R.TFHIFYQLLSGAGEHLK[136.11].S sp|P35580|MYH10_HUMAN 1 1968.0349 1.25 56957 25075 4 1968.03463 493.016 Myosin-10 OS=Homo sapiens OX=9606 GN=MYH10 PE=1 SV=3 6.61 3907.3 - 447002 - - - -0.1286 - 2.906 0.61 - 322.6 1 2 0 -0.0003 17 0 0 0 1.22E+07 9.76E+06 - - - 4.9058 1 221125_WJC_METTL3_EV_vs_WT_F04.25076.25076.3 5.16E-10 18/100 R.SSGTASSVAFTPLQGLEIVNPQAAEK.K "sp|Q8WWY3|PRP31_HUMAN,tr|E7EVX8|E7EVX8_HUMAN" 2 2601.3286 0.58 56958 25076 3 2601.332537 868.1168 U4\U6 small nuclear ribonucleoprotein Prp31 OS=Homo sapiens OX=9606 GN=PRPF31 PE=1 SV=2 4.53 3907.4 - 1.13E+06 - - - 1.5088 - 3.164 0.552 - 241.8 1 2 0 0.0039 26 0 0 0 1.01E+08 1.76E+08 - - - 7.3431 1 221125_WJC_METTL3_EV_vs_WT_F04.25079.25079.4 1.02E-08 25/252 K.LLAAYPGASGLGSAAAAAAAAASC[160.03]HLHLPPPAAPGSPGSLSLR.N sp|Q9H7S9|ZN703_HUMAN 1 3947.0476 3.5 56959 25079 4 3947.044544 987.7692 Zinc finger protein 703 OS=Homo sapiens OX=9606 GN=ZNF703 PE=1 SV=1 8.24 3907.8 - 691869 - - - -0.7717 - 3.766 0.555 - 184.6 1 2 0 -0.003 43 0 0 0 1.27E+07 3.62E+06 - - - 4.4333 1 221125_WJC_METTL3_EV_vs_WT_F04.25083.25083.3 1.90E-07 16/72 R.YVASYLLAALGGNSSPSAK[136.11].D sp|P05387|RLA2_HUMAN 1 1875.9822 1.34 56963 25083 3 1875.97916 626.3347 60S acidic ribosomal protein P2 OS=Homo sapiens OX=9606 GN=RPLP2 PE=1 SV=1 8.5 3908.3 - 505340 - - - -1.6093 - 2.835 0.514 - 243.8 1 2 0 -0.003 19 0 0 0 2.14E+07 1.60E+07 - - - 6.8298 1 221125_WJC_METTL3_EV_vs_WT_F04.25084.25084.2 0.000461 21/36 R.YVASYLLAALGGNSSPSAK.D sp|P05387|RLA2_HUMAN 1 1867.968 0.78 56964 25084 2 1867.964612 934.9913 60S acidic ribosomal protein P2 OS=Homo sapiens OX=9606 GN=RPLP2 PE=1 SV=1 8.5 3908.5 - 340460 - - - -1.8025 - 3.4 0.628 - 1295.8 1 2 0 -0.0034 19 0 0 0 1.36E+07 1.75E+07 - - - 6.6871 0.9998 221125_WJC_METTL3_EV_vs_WT_F04.25085.25085.3 0.00722 Jul-56 K.DASDDLDDLNFFNQK.K sp|P20042|IF2B_HUMAN 1 1755.7588 0.9 56965 25085 3 1755.759189 586.2602 Eukaryotic translation initiation factor 2 subunit 2 OS=Homo sapiens OX=9606 GN=EIF2S2 PE=1 SV=2 3.66 3908.6 - 233982 - - - 0.2364 - 1.431 0.475 - 61 1 2 0 0.0004 15 0 0 0 6.58E+06 7.28E+06 - - - 4.7708 1 221125_WJC_METTL3_EV_vs_WT_F04.25088.25088.3 3.01E-13 19/88 R.SAAASNLSGLSLQEAQQILNVSK.L "sp|Q9Y3D7|TIM16_HUMAN,tr|I3L3T0|I3L3T0_HUMAN,tr|A0A0A6YYL4|A0A0A6YYL4_HUMAN,tr|I3L1U7|I3L1U7_HUMAN,tr|I3L0X9|I3L0X9_HUMAN" 5 2328.2285 1.49 56966 25088 3 2328.23143 777.0834 Mitochondrial import inner membrane translocase subunit TIM16 OS=Homo sapiens OX=9606 GN=PAM16 PE=1 SV=2 5.72 3909 - 7.30E+06 - - - 1.2567 - 3.899 0.646 - 443.5 1 2 0 0.0029 23 0 0 0 9.12E+07 6.11E+07 - - - 8.9336 1 221125_WJC_METTL3_EV_vs_WT_F04.25090.25090.3 0.000389 25/80 N.VGTRPINLEPIFQGYIDSLKR.Y sp|P35908|K22E_HUMAN 1 2415.3274 999 56968 25090 3 2415.327671 806.1164 "Keratin, type II cytoskeletal 2 epidermal OS=Homo sapiens OX=9606 GN=KRT2 PE=1 SV=2" 8.56 3909.3 - 1.29E+06 - - - 0.0998 - 4.945 0.58 - 654.2 1 1 0 0.0002 21 0 0 0 3.09E+07 0.00E+00 - - - 8.8384 0.9977 221125_WJC_METTL3_EV_vs_WT_F04.25091.25091.4 6.51E-06 18/150 H.TAVVGIPHGLEDWSFFAVYDGHAGSR.V "sp|O75688|PPM1B_HUMAN,tr|B8ZZF0|B8ZZF0_HUMAN,tr|A0A3B3IS24|A0A3B3IS24_HUMAN,tr|C9JIR6|C9JIR6_HUMAN" 4 2787.3405 0.78 56969 25091 4 2787.342836 697.8424 Protein phosphatase 1B OS=Homo sapiens OX=9606 GN=PPM1B PE=1 SV=1 5.2 3909.4 - 775868 - - - 0.8331 - 3.852 0.553 - 160.1 1 1 0 0.0023 26 0 0 0 7.72E+06 9.90E+06 - - - 4.4641 1 221125_WJC_METTL3_EV_vs_WT_F04.25093.25093.2 2.73E-13 17/28 K.DASDDLDDLNFFNQK.K sp|P20042|IF2B_HUMAN 1 1755.7588 0.85 56971 25093 2 1755.758679 878.8867 Eukaryotic translation initiation factor 2 subunit 2 OS=Homo sapiens OX=9606 GN=EIF2S2 PE=1 SV=2 3.66 3909.7 - 619282 - - - -0.0541 - 3.54 0.763 - 1115.4 1 2 0 -0.0001 15 0 0 0 1.45E+07 1.71E+07 - - - 7.7844 1 221125_WJC_METTL3_EV_vs_WT_F04.25094.25094.2 0.000299 18/36 R.YVASYLLAALGGNSSPSAK[136.11].D sp|P05387|RLA2_HUMAN 1 1875.9822 0.71 56972 25094 2 1875.986082 938.9984 60S acidic ribosomal protein P2 OS=Homo sapiens OX=9606 GN=RPLP2 PE=1 SV=1 8.5 3909.8 - 613049 - - - 2.0805 - 3.561 0.605 - 815.9 1 2 0 0.0039 19 0 0 0 1.36E+07 1.92E+07 - - - 6.6308 1 221125_WJC_METTL3_EV_vs_WT_F04.25095.25095.4 6.67E-07 19/96 R.TFHIFYQLLSGAGEHLK.S sp|P35580|MYH10_HUMAN 1 1960.0207 1.25 56973 25095 4 1960.020127 491.0124 Myosin-10 OS=Homo sapiens OX=9606 GN=MYH10 PE=1 SV=3 6.61 3909.9 - 531970 - - - -0.2837 - 3.098 0.475 - 314.5 1 2 0 -0.0006 17 0 0 0 1.22E+07 9.76E+06 - - - 3.7528 1 221125_WJC_METTL3_EV_vs_WT_F04.25096.25096.2 3.84E-08 17/44 R.SAAASNLSGLSLQEAQQILNVSK.L "sp|Q9Y3D7|TIM16_HUMAN,tr|I3L3T0|I3L3T0_HUMAN,tr|A0A0A6YYL4|A0A0A6YYL4_HUMAN,tr|I3L1U7|I3L1U7_HUMAN,tr|I3L0X9|I3L0X9_HUMAN" 5 2328.2285 1.52 56974 25096 2 2328.226923 1165.1215 Mitochondrial import inner membrane translocase subunit TIM16 OS=Homo sapiens OX=9606 GN=PAM16 PE=1 SV=2 5.72 3910 - 522824 - - - -0.6791 - 4.033 0.704 - 809.9 1 2 0 -0.0016 23 0 0 0 6.82E+06 4.49E+06 - - - 7.6687 1 221125_WJC_METTL3_EV_vs_WT_F04.25098.25098.3 2.66E-07 13/56 K.DASDDLDDLNFFNQK[136.11].K sp|P20042|IF2B_HUMAN 1 1763.773 0.9 56976 25098 3 1763.77223 588.9316 Eukaryotic translation initiation factor 2 subunit 2 OS=Homo sapiens OX=9606 GN=EIF2S2 PE=1 SV=2 3.66 3910.3 - 388995 - - - -0.4218 - 2.348 0.614 - 236.3 1 2 0 -0.0007 15 0 0 0 6.58E+06 7.28E+06 - - - 7.6125 1 221125_WJC_METTL3_EV_vs_WT_F04.25100.25100.3 0.000277 15/60 K.K[136.11]VSQEILELLNTTTAK[136.11].E "sp|Q86U44|MTA70_HUMAN,tr|H0YFV6|H0YFV6_HUMAN" 2 1803.0324 0.01 56977 25100 3 1803.031995 602.0181 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 6.14 3910.5 - 1.36E+06 - - - -0.2413 - 3.563 0.64 - 436.1 1 2 0 -0.0004 16 0 0 0 1.06E+06 1.61E+08 - - - 8.9354 1 221125_WJC_METTL3_EV_vs_WT_F04.25104.25104.3 4.44E-12 23/108 K.SPTSVGAFPSTSAFGQEAGEIVNSGFGK.T sp|O60318|GANP_HUMAN 1 2728.298 1.66 56979 25104 3 2728.296453 910.44 Germinal-center associated nuclear protein OS=Homo sapiens OX=9606 GN=MCM3AP PE=1 SV=2 4.53 3911 - 931942 - - - -0.5817 - 4.212 0.585 - 563.8 1 2 0 -0.0016 28 0 0 0 1.22E+07 7.35E+06 - - - 8.3699 1 221125_WJC_METTL3_EV_vs_WT_F04.25111.25111.4 0.000712 17/114 K.SEVLSESSELLQQELEELR[166.11]K[136.11].S "sp|Q15643|TRIPB_HUMAN,tr|H0YJ97|H0YJ97_HUMAN" 2 2363.2187 1.37 56984 25111 4 2363.219245 591.8119 Thyroid receptor-interacting protein 11 OS=Homo sapiens OX=9606 GN=TRIP11 PE=1 SV=3 4.21 3912 - 423910 - - - 0.2433 - 3.398 0.528 - 210.9 1 2 0 0.0006 20 0 0 0 8.60E+06 6.28E+06 - - - 4.2305 1 221125_WJC_METTL3_EV_vs_WT_F04.25112.25112.4 1.23E-05 14/132 R.YVHIPDDVNITSTIEQQLQIIHR.V sp|Q969L4|LSM10_HUMAN 1 2731.4293 2.07 56985 25112 4 2731.425638 683.8646 U7 snRNA-associated Sm-like protein LSm10 OS=Homo sapiens OX=9606 GN=LSM10 PE=1 SV=1 5.21 3912.1 - 307196 - - - -1.3513 - 3.132 0.468 - 119.2 1 2 0 -0.0037 23 0 0 0 4.53E+06 2.19E+06 - - - 3.6683 1 221125_WJC_METTL3_EV_vs_WT_F04.25115.25115.3 3.10E-11 24/100 R.SSGTASSVAFTPLQGLEIVNPQAAEK[136.11].K "sp|Q8WWY3|PRP31_HUMAN,tr|E7EVX8|E7EVX8_HUMAN" 2 2609.3428 2.5 56987 25115 3 2609.342598 870.7882 U4\U6 small nuclear ribonucleoprotein Prp31 OS=Homo sapiens OX=9606 GN=PRPF31 PE=1 SV=2 4.53 3912.4 - 2.20E+06 - - - -0.082 - 3.876 0.629 - 471.4 1 2 0 -0.0002 26 0 0 0 9.46E+07 3.78E+07 - - - 8.6696 1 221125_WJC_METTL3_EV_vs_WT_F04.25117.25117.3 5.63E-10 26/76 K.SEVLSESSELLQQELEELR[166.11]K[136.11].S "sp|Q15643|TRIPB_HUMAN,tr|H0YJ97|H0YJ97_HUMAN" 2 2363.2187 1.11 56988 25117 3 2363.2166 788.7468 Thyroid receptor-interacting protein 11 OS=Homo sapiens OX=9606 GN=TRIP11 PE=1 SV=3 4.21 3912.7 - 3.46E+06 - - - -0.8759 - 4.488 0.555 - 648 1 2 0 -0.0021 20 0 0 0 3.64E+07 3.28E+07 - - - 8.3696 0.9999 221125_WJC_METTL3_EV_vs_WT_F04.25118.25118.3 0.000192 Dec-60 R.ETDLQELFR[166.11]PFGSISR[166.11].L "sp|O75821|EIF3G_HUMAN,tr|K7EP16|K7EP16_HUMAN,tr|K7ENA8|K7ENA8_HUMAN" 3 1913.975 0.88 56989 25118 3 1913.974296 638.9989 Eukaryotic translation initiation factor 3 subunit G OS=Homo sapiens OX=9606 GN=EIF3G PE=1 SV=2 4.68 3912.8 - 314268 - - - -0.3767 - 2.706 0.401 - 224.3 1 2 0 -0.0007 16 0 0 0 4.20E+06 4.78E+06 - - - 5.5648 1 221125_WJC_METTL3_EV_vs_WT_F04.25119.25119.3 5.15E-09 20/96 K.KEEQVISLGPQVAEGENVFGVC[160.03]HIF.A "sp|P62263|RS14_HUMAN,tr|A0A2R8Y811|A0A2R8Y811_HUMAN,tr|E5RH77|E5RH77_HUMAN" 3 2785.3745 1.42 56990 25119 3 2785.376092 929.4654 40S ribosomal protein S14 OS=Homo sapiens OX=9606 GN=RPS14 PE=1 SV=3 4.48 3912.9 - 777362 - - - 0.5658 - 3.983 0.654 - 480.8 1 1 0 0.0016 25 0 0 0 1.24E+07 8.70E+06 - - - 9.0106 1 221125_WJC_METTL3_EV_vs_WT_F04.25120.25120.4 2.37E-07 20/114 K.SEVLSESSELLQQELEELRK.S "sp|Q15643|TRIPB_HUMAN,tr|H0YJ97|H0YJ97_HUMAN" 2 2345.1962 1.37 56991 25120 4 2345.197399 587.3063 Thyroid receptor-interacting protein 11 OS=Homo sapiens OX=9606 GN=TRIP11 PE=1 SV=3 4.21 3913 - 777335 - - - 0.5113 - 3.418 0.591 - 320.4 1 2 0 0.0012 20 0 0 0 8.60E+06 6.28E+06 - - - 4.7806 1 221125_WJC_METTL3_EV_vs_WT_F04.25121.25121.3 1.30E-08 14/68 K.DKPVYDELFYTLSPINGK.L sp|Q9H223|EHD4_HUMAN 1 2098.0623 1.03 56992 25121 3 2098.061074 700.3614 EH domain-containing protein 4 OS=Homo sapiens OX=9606 GN=EHD4 PE=1 SV=1 4.56 3913.2 - 383168 - - - -0.5715 - 3.043 0.58 - 250 1 2 0 -0.0012 18 0 0 0 4.43E+06 4.29E+06 - - - 7.7772 1 221125_WJC_METTL3_EV_vs_WT_F04.25122.25122.3 0.000438 13/64 R.TFHIFYQLLSGAGEHLK[136.11].S sp|P35580|MYH10_HUMAN 1 1968.0349 36.72 56993 25122 3 1968.031362 657.0189 Myosin-10 OS=Homo sapiens OX=9606 GN=MYH10 PE=1 SV=3 6.61 3913.3 - 283846 - - - -1.7891 - 2.764 0.506 - 200.2 1 2 0 -0.0035 17 0 0 0 3.31E+08 9.02E+06 - - - 6.7489 0.9998 221125_WJC_METTL3_EV_vs_WT_F04.25129.25129.3 3.00E-06 20/64 R.NKLDLETLTDILQHQIR.A "sp|P18440|ARY1_HUMAN,tr|F5H5R8|F5H5R8_HUMAN" 2 2049.1219 1.2 56998 25129 3 2049.128492 684.0479 Arylamine N-acetyltransferase 1 OS=Homo sapiens OX=9606 GN=NAT1 PE=1 SV=2 5.38 3914.2 - 327264 - - - 3.2394 - 4.126 0.55 - 575.1 1 2 1 0.0066 17 0 0 0 1.48E+06 1.23E+06 - - - 8.2507 1 221125_WJC_METTL3_EV_vs_WT_F04.25133.25133.3 1.33E-08 23/76 K.SEVLSESSELLQQELEELRK.S "sp|Q15643|TRIPB_HUMAN,tr|H0YJ97|H0YJ97_HUMAN" 2 2345.1962 1.11 57000 25133 3 2345.199695 782.7393 Thyroid receptor-interacting protein 11 OS=Homo sapiens OX=9606 GN=TRIP11 PE=1 SV=3 4.21 3914.8 - 3.65E+06 - - - 1.4903 - 4.134 0.58 - 488.4 1 2 0 0.0035 20 0 0 0 3.64E+07 3.28E+07 - - - 8.4486 0.9997 221125_WJC_METTL3_EV_vs_WT_F04.25136.25136.4 0.000421 10/174 K.TGGAFSNALSSLNVLR[166.11]PGEIPDAAFIHAAR[166.11].K sp|Q9Y5B6|PAXB1_HUMAN 1 3071.6056 1.24 57003 25136 4 3071.615244 768.9087 PAX3- and PAX7-binding protein 1 OS=Homo sapiens OX=9606 GN=PAXBP1 PE=1 SV=2 6.42 3915.1 - 259723 - - - 3.1537 - 2.577 0.426 - 39.8 1 2 0 0.0097 30 0 0 0 2.93E+06 2.36E+06 - - - 3.2209 1 221125_WJC_METTL3_EV_vs_WT_F04.25143.25143.3 2.14E-09 17/80 R.VGSHPEGGASWLSTAANFLSR.S sp|Q9NVT9|ARMC1_HUMAN 1 2143.0447 1.55 57008 25143 3 2143.047456 715.3555 Armadillo repeat-containing protein 1 OS=Homo sapiens OX=9606 GN=ARMC1 PE=1 SV=1 6.72 3916.1 - 1.04E+06 - - - 1.3019 - 3.253 0.588 - 271.2 1 2 0 0.0028 21 0 0 0 1.20E+07 7.71E+06 - - - 7.9228 1 221125_WJC_METTL3_EV_vs_WT_F04.25146.25146.3 2.44E-10 19/80 R.VGSHPEGGASWLSTAANFLSR[166.11].S sp|Q9NVT9|ARMC1_HUMAN 1 2153.0529 1.65 57011 25146 3 2153.05335 718.6916 Armadillo repeat-containing protein 1 OS=Homo sapiens OX=9606 GN=ARMC1 PE=1 SV=1 6.72 3916.4 - 621741 - - - 0.1923 - 3.663 0.626 - 410.6 1 2 0 0.0004 21 0 0 0 1.19E+07 7.22E+06 - - - 8.6317 0.9993 221125_WJC_METTL3_EV_vs_WT_F04.25148.25148.3 0.129 Oct-60 R.QNLEPLFEQYINNLRR.Q "sp|P48668|K2C6C_HUMAN,sp|P04259|K2C6B_HUMAN,sp|P13647|K2C5_HUMAN,sp|P02538|K2C6A_HUMAN,tr|F8W0C6|F8W0C6_HUMAN" 5 2046.0647 141.05 57013 25148 3 2046.069212 683.0288 "Keratin, type II cytoskeletal 6C OS=Homo sapiens OX=9606 GN=KRT6C PE=1 SV=3" 6.14 3916.7 - 351624 - - - 2.2184 - 2.178 0.331 - 88.6 1 2 0 0.0045 16 0 0 0 1.08E+08 7.67E+05 - - - 4.2264 0.9999 221125_WJC_METTL3_EV_vs_WT_F04.25150.25150.3 4.90E-05 Dec-68 K.AKNEILDEVISLSQVTPK.H "sp|O60313|OPA1_HUMAN,tr|C9JMB8|C9JMB8_HUMAN,tr|A0A2R8YDM2|A0A2R8YDM2_HUMAN,tr|E5KLJ9|E5KLJ9_HUMAN,tr|A0A2R8Y3X5|A0A2R8Y3X5_HUMAN,tr|A0A2R8YGE5|A0A2R8YGE5_HUMAN,tr|A0A2R8YFD1|A0A2R8YFD1_HUMAN,tr|A0A2R8YE78|A0A2R8YE78_HUMAN" 8 1983.0888 2.94 57015 25150 3 1983.08967 662.0369 "Dynamin-like 120 kDa protein, mitochondrial OS=Homo sapiens OX=9606 GN=OPA1 PE=1 SV=3" 4.68 3917 - 228571 - - - 0.4276 - 2.339 0.523 - 178.5 1 2 1 0.0008 18 0 0 0 2.41E+06 8.19E+05 - - - 6.4866 1 221125_WJC_METTL3_EV_vs_WT_F04.25155.25155.3 1.19E-11 22/136 F.GGGSFGGGGFGGGGFGGGFGGGFGGDGGLLSGNEK.V "sp|P13645|K1C10_HUMAN,tr|A0A1B0GVI3|A0A1B0GVI3_HUMAN" 2 2894.2644 999 57018 25155 3 2894.263825 965.7621 "Keratin, type I cytoskeletal 10 OS=Homo sapiens OX=9606 GN=KRT10 PE=1 SV=6" 4.37 3917.6 - 563992 - - - -0.2153 - 4.051 0.686 - 292.1 1 1 0 -0.0006 35 0 0 0 5.92E+06 0.00E+00 - - - 9.4066 1 221125_WJC_METTL3_EV_vs_WT_F04.25162.25162.3 5.52E-05 22/68 K.LAQQSQALQELISELDR[166.11]R[166.11].C sp|P19474|RO52_HUMAN 1 2117.1344 1.64 57025 25162 3 2117.134561 706.7187 E3 ubiquitin-protein ligase TRIM21 OS=Homo sapiens OX=9606 GN=TRIM21 PE=1 SV=1 4.68 3918.5 - 417979 - - - 0.0897 - 3.645 0.45 - 663.5 1 2 0 0.0002 18 0 0 0 1.93E+07 1.18E+07 - - - 6.7776 0.9984 221125_WJC_METTL3_EV_vs_WT_F04.25165.25165.3 0.000924 Aug-80 K.EK[136.11]FAGGDYTTTIEAFISASGR[166.11].A sp|P07814|SYEP_HUMAN 1 2238.0923 1.81 57028 25165 3 2238.095619 747.0381 Bifunctional glutamate\proline--tRNA ligase OS=Homo sapiens OX=9606 GN=EPRS1 PE=1 SV=5 4.68 3918.9 - 227982 - - - 1.4615 - 1.732 0.407 - 67.5 1 2 1 0.0033 21 0 0 0 2.88E+06 1.59E+06 - - - 4.3936 1 221125_WJC_METTL3_EV_vs_WT_F04.25173.25173.3 6.12E-11 17/72 K.NDLSIC[160.03]GTLHSVDQYLNIK.L sp|Q9Y333|LSM2_HUMAN 1 2189.0787 3.38 57034 25173 3 2189.084931 730.7002 U6 snRNA-associated Sm-like protein LSm2 OS=Homo sapiens OX=9606 GN=LSM2 PE=1 SV=1 5.21 3920 - 381436 - - - 2.861 - 3.39 0.628 - 284.5 1 2 0 0.0063 19 0 0 0 5.23E+06 1.55E+06 - - - 8.5392 0.9971 221125_WJC_METTL3_EV_vs_WT_F04.25178.25178.4 6.61E-05 9/126 R.VLDGLHNELQTIGFQIETIGK[136.11]K[136.11].V sp|O60701|UGDH_HUMAN 1 2468.361 1.17 57039 25178 4 2468.377298 618.0975 UDP-glucose 6-dehydrogenase OS=Homo sapiens OX=9606 GN=UGDH PE=1 SV=1 5.44 3920.6 - 249222 - - - 6.6129 - 1.954 0.451 - 43.4 1 2 0 0.0163 22 0 0 0 1.16E+06 9.90E+05 - - - 3.3662 0.9999 221125_WJC_METTL3_EV_vs_WT_F04.25183.25183.3 3.25E-07 24/112 K.MK[136.11]EIAEAYLGYPVTNAVITVPAYFNDSQR[166.11].Q "sp|P0DMV8|HS71A_HUMAN,sp|P0DMV9|HS71B_HUMAN,tr|A0A0G2JIW1|A0A0G2JIW1_HUMAN" 3 3277.6448 0.15 57042 25183 3 3277.651301 1093.5556 Heat shock 70 kDa protein 1A OS=Homo sapiens OX=9606 GN=HSPA1A PE=1 SV=1 4.68 3921.3 - 784402 - - - 1.977 - 3.835 0.582 - 285.8 1 2 1 0.0065 29 0 0 0 5.16E+07 3.56E+08 - - - 8.1194 0.9989 221125_WJC_METTL3_EV_vs_WT_F04.25185.25185.3 4.27E-07 15/88 K.QKVEGTEPTTAFNLFVGNLNFNK.S "sp|P19338|NUCL_HUMAN,tr|A0A7I2V506|A0A7I2V506_HUMAN,tr|A0A7I2V699|A0A7I2V699_HUMAN,tr|A0A7I2V2U7|A0A7I2V2U7_HUMAN,tr|A0A7I2V3F3|A0A7I2V3F3_HUMAN,tr|A0A7I2V428|A0A7I2V428_HUMAN,tr|A0A7I2V349|A0A7I2V349_HUMAN,tr|H7BY16|H7BY16_HUMAN,tr|A0A7I2V5M5|A0A7I2V5M5_HUMAN,tr|A0A7I2V2S8|A0A7I2V2S8_HUMAN,tr|C9JLB1|C9JLB1_HUMAN" 11 2567.302 1.18 57044 25185 3 2567.312431 856.7746 Nucleolin OS=Homo sapiens OX=9606 GN=NCL PE=1 SV=3 6.14 3921.6 - 497512 - - - 4.0619 - 2.96 0.489 - 210.5 1 2 1 0.0104 23 0 0 0 3.84E+06 3.27E+06 - - - 6.5348 0.9997 221125_WJC_METTL3_EV_vs_WT_F04.25186.25186.3 5.46E-08 13/88 K.QK[136.11]VEGTEPTTAFNLFVGNLNFNK[136.11].S "sp|P19338|NUCL_HUMAN,tr|A0A7I2V506|A0A7I2V506_HUMAN,tr|A0A7I2V699|A0A7I2V699_HUMAN,tr|A0A7I2V2U7|A0A7I2V2U7_HUMAN,tr|A0A7I2V3F3|A0A7I2V3F3_HUMAN,tr|A0A7I2V428|A0A7I2V428_HUMAN,tr|A0A7I2V349|A0A7I2V349_HUMAN,tr|H7BY16|H7BY16_HUMAN,tr|A0A7I2V5M5|A0A7I2V5M5_HUMAN,tr|A0A7I2V2S8|A0A7I2V2S8_HUMAN,tr|C9JLB1|C9JLB1_HUMAN" 11 2583.3304 1.18 57045 25186 3 2583.337376 862.1174 Nucleolin OS=Homo sapiens OX=9606 GN=NCL PE=1 SV=3 6.14 3921.7 - 414616 - - - 2.6992 - 2.694 0.542 - 128.9 1 2 1 0.007 23 0 0 0 3.84E+06 3.27E+06 - - - 6.9057 0.9877 221125_WJC_METTL3_EV_vs_WT_F04.25191.25191.3 6.19E-06 Oct-72 K.STNGDTFLGGEDFDQALLR[166.11].H "sp|P38646|GRP75_HUMAN,tr|H0Y8K0|H0Y8K0_HUMAN,tr|A0A7I2V2S7|A0A7I2V2S7_HUMAN,tr|A0A7I2V2G2|A0A7I2V2G2_HUMAN,tr|A0A7I2V3F7|A0A7I2V3F7_HUMAN,tr|A0A7I2YQB2|A0A7I2YQB2_HUMAN,tr|D6RCD7|D6RCD7_HUMAN" 7 2064.9628 -1 57050 25191 3 2065.955546 689.3282 "Stress-70 protein, mitochondrial OS=Homo sapiens OX=9606 GN=HSPA9 PE=1 SV=2" 3.84 3922.4 - 113497 - - - 480.7656 - 2.314 0.579 - 150.9 1 2 0 0.9928 19 0 0 0 0.00E+00 0.00E+00 - - - 6.7815 1 221125_WJC_METTL3_EV_vs_WT_F04.25194.25194.3 1.17E-07 16/68 K.LAQQSQALQELISELDRR.C sp|P19474|RO52_HUMAN 1 2097.1178 1.64 57052 25194 3 2097.123331 700.0466 E3 ubiquitin-protein ligase TRIM21 OS=Homo sapiens OX=9606 GN=TRIM21 PE=1 SV=1 4.68 3922.7 - 1.40E+06 - - - 2.6226 - 3.181 0.567 - 241.2 1 2 0 0.0055 18 0 0 0 1.94E+07 1.18E+07 - - - 7.7415 1 221125_WJC_METTL3_EV_vs_WT_F04.25196.25196.4 1.05E-15 29/204 R.LC[160.03]QADPDLDSDKDETGAYLIDRDPTYFGPVLNYLR.H "sp|Q9NXV2|KCTD5_HUMAN,tr|H3BSS5|H3BSS5_HUMAN" 2 4044.9051 4.28 57053 25196 4 4044.909672 1012.2336 BTB\POZ domain-containing protein KCTD5 OS=Homo sapiens OX=9606 GN=KCTD5 PE=1 SV=1 3.94 3922.9 - 1.26E+06 - - - 1.1234 - 4.816 0.67 - 246.2 1 2 2 0.0045 35 0 0 0 1.81E+08 4.22E+07 - - - 5.5224 1 221125_WJC_METTL3_EV_vs_WT_F04.25200.25200.3 4.00E-14 24/80 K.DNFHGLAIFLDTYPNDETTER.V "sp|Q12907|LMAN2_HUMAN,tr|D6RBV2|D6RBV2_HUMAN,tr|D6RDX1|D6RDX1_HUMAN,tr|D6RIU4|D6RIU4_HUMAN" 4 2467.1292 1.54 57057 25200 3 2467.129977 823.3837 Vesicular integral-membrane protein VIP36 OS=Homo sapiens OX=9606 GN=LMAN2 PE=1 SV=1 4.1 3923.4 - 758164 - - - 0.3218 - 4.352 0.73 - 418.6 1 2 0 0.0008 21 0 0 0 1.56E+07 1.01E+07 - - - 10.2043 1 221125_WJC_METTL3_EV_vs_WT_F04.25201.25201.3 2.60E-13 25/92 R.IYSHDGTDSPPDADEVVIVLNNFK[136.11].S sp|Q9NYU2|UGGG1_HUMAN 1 2652.2799 0.1 57058 25201 3 2652.280721 885.1006 UDP-glucose:glycoprotein glucosyltransferase 1 OS=Homo sapiens OX=9606 GN=UGGT1 PE=1 SV=3 4.03 3923.5 - 743894 - - - 0.3182 - 4.443 0.748 - 577.7 1 2 0 0.0008 24 0 0 0 1.35E+06 1.34E+07 - - - 10.343 0.9999 221125_WJC_METTL3_EV_vs_WT_F04.25216.25216.4 2.11E-10 14/108 R.TDLEMQIEGLKEELAYLRK.N sp|P08779|K1C16_HUMAN 1 2278.1879 999 57071 25216 4 2278.193155 570.5542 "Keratin, type I cytoskeletal 16 OS=Homo sapiens OX=9606 GN=KRT16 PE=1 SV=4" 4.58 3925.5 - 370107 - - - 2.3137 - 3.269 0.569 - 178.9 1 2 1 0.0053 19 0 0 0 2.25E+07 0.00E+00 - - - 4.5778 0.9999 221125_WJC_METTL3_EV_vs_WT_F04.25220.25220.4 3.64E-09 25/168 K.MK[136.11]EIAEAYLGYPVTNAVITVPAYFNDSQR[166.11].Q "sp|P0DMV8|HS71A_HUMAN,sp|P0DMV9|HS71B_HUMAN,tr|A0A0G2JIW1|A0A0G2JIW1_HUMAN" 3 3277.6448 0.15 57074 25220 4 3277.644955 820.4185 Heat shock 70 kDa protein 1A OS=Homo sapiens OX=9606 GN=HSPA1A PE=1 SV=1 4.68 3925.9 - 3.58E+06 - - - 0.0409 - 4.43 0.549 - 252 1 2 1 0.0001 29 0 0 0 2.00E+07 1.35E+08 - - - 4.4632 1 221125_WJC_METTL3_EV_vs_WT_F04.25221.25221.3 1.72E-08 20/72 R.QNLDTIVQAIQHIEGTQEK.Q sp|Q01664|TFAP4_HUMAN 1 2164.1124 1.51 57075 25221 3 2164.116728 722.3781 Transcription factor AP-4 OS=Homo sapiens OX=9606 GN=TFAP4 PE=1 SV=2 4.65 3926 - 2.01E+06 - - - 1.9948 - 4.078 0.549 - 658.9 1 2 0 0.0043 19 0 0 0 2.68E+07 1.78E+07 - - - 8.1129 1 221125_WJC_METTL3_EV_vs_WT_F04.25222.25222.3 6.56E-10 28/112 K.MKEIAEAYLGYPVTNAVITVPAYFNDSQR.Q "sp|P0DMV8|HS71A_HUMAN,sp|P0DMV9|HS71B_HUMAN,tr|A0A0G2JIW1|A0A0G2JIW1_HUMAN" 3 3259.6224 0.15 57076 25222 3 3259.622868 1087.5481 Heat shock 70 kDa protein 1A OS=Homo sapiens OX=9606 GN=HSPA1A PE=1 SV=1 4.68 3926.1 - 1.31E+06 - - - 0.1586 - 4.235 0.629 - 328 1 2 1 0.0005 29 0 0 0 5.16E+07 3.56E+08 - - - 8.8733 1 221125_WJC_METTL3_EV_vs_WT_F04.25224.25224.3 5.26E-12 14/104 K.FEQLVSIGSSYNYGNEDQAEFLC[160.03]VVSK.E sp|Q9NXV2|KCTD5_HUMAN 1 3082.423 6.1 57078 25224 3 3082.426914 1028.4816 BTB\POZ domain-containing protein KCTD5 OS=Homo sapiens OX=9606 GN=KCTD5 PE=1 SV=1 4 3926.4 - 752581 - - - 1.2753 - 3.359 0.684 - 216 1 2 0 0.0039 27 0 0 0 6.26E+06 1.03E+06 - - - 8.9524 1 221125_WJC_METTL3_EV_vs_WT_F04.25227.25227.4 1.72E-10 21/132 R.GREGPVQFEEDPFGLDKFLEEAK.Q "sp|Q13573|SNW1_HUMAN,tr|G3V4X8|G3V4X8_HUMAN" 2 2636.2758 2.87 57081 25227 4 2636.274616 660.0762 SNW domain-containing protein 1 OS=Homo sapiens OX=9606 GN=SNW1 PE=1 SV=1 4.25 3926.8 - 287721 - - - -0.4673 - 4.01 0.619 - 298.5 1 2 2 -0.0012 23 0 0 0 1.79E+06 6.23E+05 - - - 5.0634 1 221125_WJC_METTL3_EV_vs_WT_F04.25229.25229.4 1.09E-10 22/138 R.LAQENEVDFILLGGDLFHENKPSR.K "sp|P49959|MRE11_HUMAN,tr|F5GXT0|F5GXT0_HUMAN,tr|F5H256|F5H256_HUMAN,tr|F8W7U8|F8W7U8_HUMAN,tr|F5H742|F5H742_HUMAN" 5 2740.382 1.45 57083 25229 4 2740.387177 686.1028 Double-strand break repair protein MRE11 OS=Homo sapiens OX=9606 GN=MRE11 PE=1 SV=3 4.5 3927.1 - 213887 - - - 1.8731 - 3.854 0.615 - 307.7 1 2 0 0.0051 24 0 0 0 3.75E+06 2.58E+06 - - - 5.0106 1 221125_WJC_METTL3_EV_vs_WT_F04.25232.25232.4 1.01E-16 35/258 R.FGGFGGPGGVGGLGGPGGFGPGGYPGGIHEVSVNQSLLQPLNVK.V sp|P35908|K22E_HUMAN 1 4091.0653 128.15 57084 25232 4 4091.069083 1023.7736 "Keratin, type II cytoskeletal 2 epidermal OS=Homo sapiens OX=9606 GN=KRT2 PE=1 SV=2" 6.75 3927.4 - 2.23E+06 - - - 0.9127 - 5.212 0.651 - 314.4 1 2 0 0.0037 44 0 0 0 4.77E+07 3.72E+05 - - - 5.3591 1 221125_WJC_METTL3_EV_vs_WT_F04.25234.25234.4 8.95E-09 20/138 R.LAQENEVDFILLGGDLFHENK[136.11]PSR[166.11].K "sp|P49959|MRE11_HUMAN,tr|F5GXT0|F5GXT0_HUMAN,tr|F5H256|F5H256_HUMAN,tr|F8W7U8|F8W7U8_HUMAN,tr|F5H742|F5H742_HUMAN" 5 2758.4045 1.67 57086 25234 4 2758.401423 690.6084 Double-strand break repair protein MRE11 OS=Homo sapiens OX=9606 GN=MRE11 PE=1 SV=3 4.5 3927.7 - 705624 - - - -1.1206 - 3.683 0.592 - 241.1 1 2 0 -0.0031 24 0 0 0 4.30E+06 2.58E+06 - - - 4.7964 1 221125_WJC_METTL3_EV_vs_WT_F04.25235.25235.3 2.18E-09 23/104 K.MFFDAELSQMQTHVSDTSVVLSMDNNR.N "sp|P13647|K2C5_HUMAN,tr|H0YI76|H0YI76_HUMAN,tr|H0YIN9|H0YIN9_HUMAN" 3 3101.3893 -1 57087 25235 3 3101.37529 1034.8037 "Keratin, type II cytoskeletal 5 OS=Homo sapiens OX=9606 GN=KRT5 PE=1 SV=3" 4.22 3927.8 - 522519 - - - -4.5031 - 4.26 0.692 - 441.5 1 2 0 -0.014 27 0 0 0 0.00E+00 0.00E+00 - - - 9.5855 0.9997 221125_WJC_METTL3_EV_vs_WT_F04.25236.25236.3 4.19E-06 13/80 K.RPLEATFDLGIPQAVLPPLPK.R "sp|Q9NR56|MBNL1_HUMAN,tr|Q86VM6|Q86VM6_HUMAN,tr|A0A0A0MQX8|A0A0A0MQX8_HUMAN,tr|C9JP00|C9JP00_HUMAN" 4 2271.2991 3.26 57088 25236 3 2271.308171 758.107 Muscleblind-like protein 1 OS=Homo sapiens OX=9606 GN=MBNL1 PE=1 SV=2 6.07 3928 - 439844 - - - 3.9982 - 2.129 0.534 - 146.2 1 2 0 0.0091 21 0 0 0 4.76E+06 1.46E+06 - - - 6.3027 1 221125_WJC_METTL3_EV_vs_WT_F04.25243.25243.4 1.06E-10 27/168 K.MKEIAEAYLGYPVTNAVITVPAYFNDSQR.Q "sp|P0DMV8|HS71A_HUMAN,sp|P0DMV9|HS71B_HUMAN,tr|A0A0G2JIW1|A0A0G2JIW1_HUMAN" 3 3259.6224 0.15 57093 25243 4 3259.61989 815.9129 Heat shock 70 kDa protein 1A OS=Homo sapiens OX=9606 GN=HSPA1A PE=1 SV=1 4.68 3928.9 - 2.47E+06 - - - -0.755 - 4.33 0.627 - 274.6 1 2 1 -0.0025 29 0 0 0 2.00E+07 1.35E+08 - - - 5.1344 0.9955 221125_WJC_METTL3_EV_vs_WT_F04.25245.25245.4 3.86E-06 15/132 S.RTLTAVHDAILEDLVFPSEIVGK.R "sp|P62081|RS7_HUMAN,tr|B5MCP9|B5MCP9_HUMAN,tr|A0A2R8Y623|A0A2R8Y623_HUMAN" 3 2522.3744 0.93 57095 25245 4 2522.375661 631.6009 40S ribosomal protein S7 OS=Homo sapiens OX=9606 GN=RPS7 PE=1 SV=1 4.75 3929.1 - 325020 - - - 0.4841 - 2.588 0.496 - 136.9 1 1 0 0.0012 23 0 0 0 2.89E+06 3.11E+06 - - - 3.8509 1 221125_WJC_METTL3_EV_vs_WT_F04.25254.25254.3 5.51E-13 20/172 R.FGGFGGPGGVGGLGGPGGFGPGGYPGGIHEVSVNQSLLQPLNVK.V sp|P35908|K22E_HUMAN 1 4091.0653 999 57101 25254 3 4091.060499 1364.6957 "Keratin, type II cytoskeletal 2 epidermal OS=Homo sapiens OX=9606 GN=KRT2 PE=1 SV=2" 6.75 3930.2 - 1.25E+06 - - - -1.1855 - 4.208 0.682 - 104 1 2 0 -0.0049 44 0 0 0 7.55E+06 0.00E+00 - - - 9.4483 1 221125_WJC_METTL3_EV_vs_WT_F04.25256.25256.4 3.32E-17 40/228 K.FAESTEISELSHNFVMVNLEDEEEPKDEDFSPDGGYIPR.L sp|O95881|TXD12_HUMAN 1 4470.9962 1.52 57103 25256 4 4470.989123 1118.7563 Thioredoxin domain-containing protein 12 OS=Homo sapiens OX=9606 GN=TXNDC12 PE=1 SV=1 3.88 3930.5 - 1.79E+06 - - - -1.58 - 6.391 0.734 - 598.9 1 2 1 -0.0071 39 0 0 0 9.75E+06 6.43E+06 - - - 6.1509 0.9529 221125_WJC_METTL3_EV_vs_WT_F04.25257.25257.3 0.000107 25/84 M.ADPPWDIHMELPYGTLTDDEMR[166.11].R sp|Q86U44|MTA70_HUMAN 1 2611.1598 0.04 57104 25257 3 2612.159711 871.3939 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 3.96 3930.6 - 1.42E+06 - - - 382.9203 - 3.478 0.578 - 611.5 1 1 0 0.9999 22 0 0 0 5.38E+05 1.37E+07 - - - 7.6623 0.9985 221125_WJC_METTL3_EV_vs_WT_F04.25259.25259.3 3.34E-06 Nov-72 R.GFASQVEQLISMGANVHSK[136.11].A "sp|Q9H6S0|YTDC2_HUMAN,tr|D6RA70|D6RA70_HUMAN" 2 2010.0084 0.18 57106 25259 3 2009.995986 671.0101 3'-5' RNA helicase YTHDC2 OS=Homo sapiens OX=9606 GN=YTHDC2 PE=1 SV=2 6.75 3930.9 - 461701 - - - -6.1811 - 2.456 0.482 - 117.8 1 2 0 -0.0124 19 0 0 0 3.17E+05 1.77E+06 - - - 6.1179 1 221125_WJC_METTL3_EV_vs_WT_F04.25260.25260.3 7.53E-10 26/60 R.RGVMLAVDAVIAELKK.Q "sp|P10809|CH60_HUMAN,tr|A0A7I2V2X6|A0A7I2V2X6_HUMAN,tr|A0A7I2V599|A0A7I2V599_HUMAN,tr|E7EXB4|E7EXB4_HUMAN,tr|A0A7I2YQ71|A0A7I2YQ71_HUMAN,tr|E7ESH4|E7ESH4_HUMAN,tr|A0A7I2V5M1|A0A7I2V5M1_HUMAN,tr|A0A7I2V5K3|A0A7I2V5K3_HUMAN,tr|A0A7I2V369|A0A7I2V369_HUMAN" 9 1712.0019 1.19 57107 25260 3 1711.999291 571.6746 "60 kDa heat shock protein, mitochondrial OS=Homo sapiens OX=9606 GN=HSPD1 PE=1 SV=2" 8.59 3931 - 304555 - - - -1.5018 - 4.392 0.563 - 1197.3 1 2 0 -0.0026 16 0 0 0 3.47E+07 2.93E+07 - - - 8.6131 1 221125_WJC_METTL3_EV_vs_WT_F04.25264.25264.3 4.39E-06 24/60 R.R[166.11]GVMLAVDAVIAELK[136.11]K[136.11].Q "sp|P10809|CH60_HUMAN,tr|A0A7I2V2X6|A0A7I2V2X6_HUMAN,tr|A0A7I2V599|A0A7I2V599_HUMAN,tr|E7EXB4|E7EXB4_HUMAN,tr|A0A7I2YQ71|A0A7I2YQ71_HUMAN,tr|E7ESH4|E7ESH4_HUMAN,tr|A0A7I2V5M1|A0A7I2V5M1_HUMAN,tr|A0A7I2V5K3|A0A7I2V5K3_HUMAN,tr|A0A7I2V369|A0A7I2V369_HUMAN" 9 1738.0385 1.19 57109 25264 3 1738.038892 580.3535 "60 kDa heat shock protein, mitochondrial OS=Homo sapiens OX=9606 GN=HSPD1 PE=1 SV=2" 8.59 3931.6 - 987585 - - - 0.2071 - 4.034 0.644 - 811.8 1 2 0 0.0004 16 0 0 0 3.47E+07 2.93E+07 - - - 9.2986 1 221125_WJC_METTL3_EV_vs_WT_F04.25267.25267.4 5.08E-20 33/258 R.LGSAGGLGSTLGGSSYSSC[160.03]YSFGSGGGYGSSFGGVDGLLAGGEK.A "sp|Q04695|K1C17_HUMAN,tr|K7EPJ9|K7EPJ9_HUMAN" 2 4023.8069 999 57112 25267 4 4023.805046 1006.959 "Keratin, type I cytoskeletal 17 OS=Homo sapiens OX=9606 GN=KRT17 PE=1 SV=2" 4.37 3931.9 - 1.53E+06 - - - -0.4533 - 5.479 0.724 - 417.4 1 2 0 -0.0018 44 0 0 0 6.88E+06 0.00E+00 - - - 6.0091 0.9997 221125_WJC_METTL3_EV_vs_WT_F04.25271.25271.4 1.23E-08 18/90 R.R[166.11]GVMLAVDAVIAELK[136.11]K[136.11].Q "sp|P10809|CH60_HUMAN,tr|A0A7I2V2X6|A0A7I2V2X6_HUMAN,tr|A0A7I2V599|A0A7I2V599_HUMAN,tr|E7EXB4|E7EXB4_HUMAN,tr|A0A7I2YQ71|A0A7I2YQ71_HUMAN,tr|E7ESH4|E7ESH4_HUMAN,tr|A0A7I2V5M1|A0A7I2V5M1_HUMAN,tr|A0A7I2V5K3|A0A7I2V5K3_HUMAN,tr|A0A7I2V369|A0A7I2V369_HUMAN" 9 1738.0385 1.13 57116 25271 4 1738.03724 435.5169 "60 kDa heat shock protein, mitochondrial OS=Homo sapiens OX=9606 GN=HSPD1 PE=1 SV=2" 8.59 3932.5 - 589721 - - - -0.7434 - 2.949 0.347 - 303.6 1 2 0 -0.0013 16 0 0 0 1.83E+07 1.62E+07 - - - 2.6269 1 221125_WJC_METTL3_EV_vs_WT_F04.25272.25272.4 1.10E-07 22/90 R.RGVMLAVDAVIAELKK.Q "sp|P10809|CH60_HUMAN,tr|A0A7I2V2X6|A0A7I2V2X6_HUMAN,tr|A0A7I2V599|A0A7I2V599_HUMAN,tr|E7EXB4|E7EXB4_HUMAN,tr|A0A7I2YQ71|A0A7I2YQ71_HUMAN,tr|E7ESH4|E7ESH4_HUMAN,tr|A0A7I2V5M1|A0A7I2V5M1_HUMAN,tr|A0A7I2V5K3|A0A7I2V5K3_HUMAN,tr|A0A7I2V369|A0A7I2V369_HUMAN" 9 1712.0019 1.13 57117 25272 4 1712.001336 429.0077 "60 kDa heat shock protein, mitochondrial OS=Homo sapiens OX=9606 GN=HSPD1 PE=1 SV=2" 8.59 3932.6 - 548553 - - - -0.3072 - 3.194 0.604 - 438.4 1 2 0 -0.0005 16 0 0 0 1.83E+07 1.62E+07 - - - 4.8921 0.9996 221125_WJC_METTL3_EV_vs_WT_F04.25275.25275.3 0.0126 Oct-76 K.GNPQGFNQGLDC[160.03]DVIVAEVR[166.11].S sp|Q86U44|MTA70_HUMAN 1 2197.0461 0.001 57120 25275 3 2197.049392 733.356 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 4.03 3933 - 291662 - - - 1.482 - 1.974 0.376 - 104.8 1 2 0 0.0033 20 0 0 0 0.00E+00 2.92E+06 - - - 4.381 1 221125_WJC_METTL3_EV_vs_WT_F04.25280.25280.3 3.38E-20 38/112 K.SEAAVPPWVDTNDEETIQQQILALSADKR.N sp|Q96A49|SYAP1_HUMAN 1 3223.5997 1.57 57123 25280 3 3223.597636 1075.5405 Synapse-associated protein 1 OS=Homo sapiens OX=9606 GN=SYAP1 PE=1 SV=1 4.02 3933.6 - 3.85E+06 - - - -0.6406 - 5.215 0.745 - 1038 1 2 0 -0.0021 29 0 0 0 1.72E+08 1.09E+08 - - - 10.645 1 221125_WJC_METTL3_EV_vs_WT_F04.25281.25281.3 1.13E-11 29/112 K.SEAAVPPWVDTNDEETIQQQILALSADK[136.11]R[166.11].N sp|Q96A49|SYAP1_HUMAN 1 3241.6222 1.57 57124 25281 3 3241.616449 1081.548 Synapse-associated protein 1 OS=Homo sapiens OX=9606 GN=SYAP1 PE=1 SV=1 4.02 3933.8 - 3.40E+06 - - - -1.7652 - 4.076 0.657 - 392.1 1 2 0 -0.0057 29 0 0 0 1.72E+08 1.09E+08 - - - 9.096 1 221125_WJC_METTL3_EV_vs_WT_F04.25282.25282.4 6.68E-16 33/168 K.SEAAVPPWVDTNDEETIQQQILALSADKR.N sp|Q96A49|SYAP1_HUMAN 1 3223.5997 1.77 57125 25282 4 3223.598478 806.9072 Synapse-associated protein 1 OS=Homo sapiens OX=9606 GN=SYAP1 PE=1 SV=1 4.02 3933.9 - 2.71E+06 - - - -0.3794 - 4.531 0.734 - 715.2 1 2 0 -0.0012 29 0 0 0 6.81E+07 3.85E+07 - - - 6.0801 1 221125_WJC_METTL3_EV_vs_WT_F04.25283.25283.3 1.56E-07 15/60 R.NVQALEIELQSQLALK.Q "sp|P13645|K1C10_HUMAN,tr|A0A1B0GVI3|A0A1B0GVI3_HUMAN" 2 1796.0044 0.2 57126 25283 3 1796.004931 599.6754 "Keratin, type I cytoskeletal 10 OS=Homo sapiens OX=9606 GN=KRT10 PE=1 SV=6" 4.53 3934 - 2.03E+06 - - - 0.3157 - 2.961 0.577 - 392.5 1 2 0 0.0006 16 0 0 0 1.01E+07 5.04E+07 - - - 7.7581 1 221125_WJC_METTL3_EV_vs_WT_F04.25284.25284.3 1.67E-17 18/172 R.LGSAGGLGSTLGGSSYSSC[160.03]YSFGSGGGYGSSFGGVDGLLAGGEK.A "sp|Q04695|K1C17_HUMAN,tr|K7EPJ9|K7EPJ9_HUMAN" 2 4023.8069 999 57127 25284 3 4023.807831 1342.2762 "Keratin, type I cytoskeletal 17 OS=Homo sapiens OX=9606 GN=KRT17 PE=1 SV=2" 4.37 3934.1 - 1.29E+06 - - - 0.2388 - 3.989 0.834 - 174 1 2 0 0.001 44 0 0 0 6.97E+06 0.00E+00 - - - 11.021 1 221125_WJC_METTL3_EV_vs_WT_F04.25291.25291.4 4.39E-12 23/168 K.SEAAVPPWVDTNDEETIQQQILALSADK[136.11]R[166.11].N sp|Q96A49|SYAP1_HUMAN 1 3241.6222 1.76 57132 25291 4 3241.613792 811.4128 Synapse-associated protein 1 OS=Homo sapiens OX=9606 GN=SYAP1 PE=1 SV=1 4.02 3934.9 - 6.39E+06 - - - -2.5848 - 3.688 0.719 - 267.9 1 2 0 -0.0084 29 0 0 0 6.79E+07 3.85E+07 - - - 5.8841 0.9982 221125_WJC_METTL3_EV_vs_WT_F04.25293.25293.3 2.07E-09 16/72 H.AASDVDLEIESLLNQQSTK[136.11].E "sp|Q86U44|MTA70_HUMAN,tr|F5H6D8|F5H6D8_HUMAN,tr|H0YFV6|H0YFV6_HUMAN,tr|B4DTN4|B4DTN4_HUMAN" 4 2068.0415 0.19 57134 25293 3 2068.041184 690.3545 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 3.92 3935.1 - 1.81E+06 - - - -0.1741 - 3.189 0.527 - 344.3 1 1 0 -0.0004 19 0 0 0 1.95E+06 1.05E+07 - - - 7.2646 1 221125_WJC_METTL3_EV_vs_WT_F04.25296.25296.3 8.57E-13 23/80 K.WGDAGAEYVVESTGVFTTMEK.A "sp|P04406|G3P_HUMAN,tr|E7EUT5|E7EUT5_HUMAN" 2 2276.0307 1.01 57137 25296 3 2276.028847 759.6842 Glyceraldehyde-3-phosphate dehydrogenase OS=Homo sapiens OX=9606 GN=GAPDH PE=1 SV=3 4 3935.5 - 1.58E+06 - - - -0.8207 - 4.101 0.672 - 758.1 1 2 0 -0.0019 21 0 0 0 8.47E+06 8.34E+06 - - - 9.415 0.9886 221125_WJC_METTL3_EV_vs_WT_F04.25298.25298.2 0.955 30-Jul R.NVQALEIELQSQLALK.Q "sp|P13645|K1C10_HUMAN,tr|A0A1B0GVI3|A0A1B0GVI3_HUMAN" 2 1796.0044 1 57139 25298 2 1796.006897 899.0095 "Keratin, type I cytoskeletal 10 OS=Homo sapiens OX=9606 GN=KRT10 PE=1 SV=6" 4.53 3935.8 - 447359 - - - 1.4104 - 1.277 0.165 - 76.5 1 2 0 0.0025 16 0 0 0 3.10E+06 3.09E+06 - - - 0.86 1 221125_WJC_METTL3_EV_vs_WT_F04.25304.25304.3 1.87E-12 17/80 K.WGDAGAEYVVESTGVFTTMEK[136.11].A "sp|P04406|G3P_HUMAN,tr|E7EUT5|E7EUT5_HUMAN" 2 2284.0449 1.01 57143 25304 3 2284.041837 762.3556 Glyceraldehyde-3-phosphate dehydrogenase OS=Homo sapiens OX=9606 GN=GAPDH PE=1 SV=3 4 3936.4 - 1.62E+06 - - - -1.3476 - 3.269 0.69 - 401.9 1 2 0 -0.0031 21 0 0 0 8.47E+06 8.34E+06 - - - 9.0717 1 221125_WJC_METTL3_EV_vs_WT_F04.25308.25308.3 3.20E-10 20/104 R.GNSSSPAPAASITSMLSPSFTPTSVIR[166.11].K "sp|Q9NRA8|4ET_HUMAN,tr|B1AKL4|B1AKL4_HUMAN" 2 2672.3355 1.52 57144 25308 3 2672.328864 891.7858 Eukaryotic translation initiation factor 4E transporter OS=Homo sapiens OX=9606 GN=EIF4ENIF1 PE=1 SV=2 9.75 3937 - 1.53E+06 - - - -2.4836 - 3.247 0.565 - 216.5 1 2 0 -0.0066 27 0 0 0 8.82E+07 5.81E+07 - - - 7.5469 1 221125_WJC_METTL3_EV_vs_WT_F04.25309.25309.3 3.17E-13 23/104 R.GNSSSPAPAASITSMLSPSFTPTSVIR.K "sp|Q9NRA8|4ET_HUMAN,tr|B1AKL4|B1AKL4_HUMAN" 2 2662.3272 1.56 57145 25309 3 2662.321085 888.4497 Eukaryotic translation initiation factor 4E transporter OS=Homo sapiens OX=9606 GN=EIF4ENIF1 PE=1 SV=2 9.75 3937.1 - 1.94E+06 - - - -2.3085 - 4.016 0.652 - 298.2 1 2 0 -0.0061 27 0 0 0 9.06E+07 5.83E+07 - - - 9.006 0.9999 221125_WJC_METTL3_EV_vs_WT_F04.25310.25310.3 6.02E-09 17/76 K.DKVVLDVGSGTGILC[160.03]MFAAK.A "sp|Q99873|ANM1_HUMAN,tr|E9PQ98|E9PQ98_HUMAN,tr|E9PKG1|E9PKG1_HUMAN,tr|E9PNR9|E9PNR9_HUMAN,tr|H0YDE4|H0YDE4_HUMAN,tr|E9PMW9|E9PMW9_HUMAN,tr|E9PIX6|E9PIX6_HUMAN" 7 2080.0697 0.51 57146 25310 3 2080.064274 694.3638 Protein arginine N-methyltransferase 1 OS=Homo sapiens OX=9606 GN=PRMT1 PE=1 SV=3 5.95 3937.3 - 616850 - - - -2.6009 - 3.655 0.59 - 404.2 1 2 1 -0.0054 20 0 0 0 3.60E+06 7.07E+06 - - - 8.2608 0.9935 221125_WJC_METTL3_EV_vs_WT_F04.25319.25319.4 2.24E-10 24/132 Q.MNVGTRPINLEPIFQGYIDSLKR.Y sp|P35908|K22E_HUMAN 1 2660.4108 281.94 57151 25319 4 2660.401637 666.11 "Keratin, type II cytoskeletal 2 epidermal OS=Homo sapiens OX=9606 GN=KRT2 PE=1 SV=2" 8.34 3938.4 - 904344 - - - -3.46 - 3.489 0.619 - 307.4 1 1 0 -0.0092 23 0 0 0 4.96E+07 1.76E+05 - - - 5.0161 1 221125_WJC_METTL3_EV_vs_WT_F04.25339.25339.3 4.41E-10 16/60 K.K[136.11]VSQEILELLNTTTAK[136.11].E "sp|Q86U44|MTA70_HUMAN,tr|H0YFV6|H0YFV6_HUMAN" 2 1803.0324 0.02 57162 25339 3 1803.028121 602.0181 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 6.14 3940.8 - 2.69E+06 - - - -2.3899 - 3.605 0.649 - 472.6 1 2 0 -0.0043 16 0 0 0 1.27E+06 5.93E+07 - - - 9.0648 0.9898 221125_WJC_METTL3_EV_vs_WT_F04.25342.25342.3 0.00104 13/88 K.GNVQVVIPFLTESYSSSQDPPEK.S sp|P22314|UBA1_HUMAN 1 2520.2384 0.67 57163 25342 3 2520.226979 841.0867 Ubiquitin-like modifier-activating enzyme 1 OS=Homo sapiens OX=9606 GN=UBA1 PE=1 SV=3 4.14 3941.2 - 488977 - - - -4.5317 - 1.634 0.332 - 98.8 1 2 0 -0.0114 23 0 0 0 8.19E+06 1.22E+07 - - - 3.3902 1 221125_WJC_METTL3_EV_vs_WT_F04.25356.25356.3 1.42E-14 27/72 K.FNLLAHLADDLGHVVPNSR.L sp|Q8N5N7|RM50_HUMAN 1 2087.0912 1.32 57168 25356 3 2087.085595 696.7044 "39S ribosomal protein L50, mitochondrial OS=Homo sapiens OX=9606 GN=MRPL50 PE=1 SV=2" 5.98 3943 - 1.21E+06 - - - -2.6961 - 4.677 0.685 - 907.1 1 2 0 -0.0056 19 0 0 0 1.76E+07 1.33E+07 - - - 9.9655 1 221125_WJC_METTL3_EV_vs_WT_F04.25358.25358.4 3.85E-07 26/108 K.FNLLAHLADDLGHVVPNSR.L sp|Q8N5N7|RM50_HUMAN 1 2087.0912 1.19 57170 25358 4 2087.087045 522.7801 "39S ribosomal protein L50, mitochondrial OS=Homo sapiens OX=9606 GN=MRPL50 PE=1 SV=2" 5.98 3943.2 - 1.69E+06 - - - -2.0013 - 3.921 0.523 - 480.4 1 2 0 -0.0042 19 0 0 0 2.96E+07 2.48E+07 - - - 4.2392 0.9983 221125_WJC_METTL3_EV_vs_WT_F04.25364.25364.4 8.83E-09 26/108 K.FNLLAHLADDLGHVVPNSR[166.11].L sp|Q8N5N7|RM50_HUMAN 1 2097.0995 1.17 57173 25364 4 2098.09803 525.2821 "39S ribosomal protein L50, mitochondrial OS=Homo sapiens OX=9606 GN=MRPL50 PE=1 SV=2" 5.98 3944 - 1.21E+06 - - - 476.1519 - 3.869 0.533 - 496.2 1 2 0 0.9985 19 0 0 0 2.97E+07 2.54E+07 - - - 4.0463 1 221125_WJC_METTL3_EV_vs_WT_F04.25365.25365.3 2.59E-10 22/116 K.ETGANLAIC[160.03]QWGFDDEANHLLLQNNLPAVR[166.11].W "sp|P48643|TCPE_HUMAN,tr|E9PCA1|E9PCA1_HUMAN,tr|B7ZAR1|B7ZAR1_HUMAN,tr|E7ENZ3|E7ENZ3_HUMAN" 4 3388.6498 0.61 57174 25365 3 3388.644963 1130.5572 T-complex protein 1 subunit epsilon OS=Homo sapiens OX=9606 GN=CCT5 PE=1 SV=1 4.31 3944.1 - 1.43E+06 - - - -1.4256 - 3.714 0.612 - 446.3 1 2 0 -0.0048 30 0 0 0 6.63E+06 1.08E+07 - - - 8.3805 1 221125_WJC_METTL3_EV_vs_WT_F04.25366.25366.3 4.25E-12 21/68 K.GHYTEGAELVDSVLDVVR[166.11].K "sp|Q9BVA1|TBB2B_HUMAN,sp|P07437|TBB5_HUMAN,sp|Q13509|TBB3_HUMAN,sp|Q13885|TBB2A_HUMAN,sp|P68371|TBB4B_HUMAN,tr|A0A0B4J269|A0A0B4J269_HUMAN,tr|Q5ST81|Q5ST81_HUMAN,tr|Q5JP53|Q5JP53_HUMAN,tr|G3V2A3|G3V2A3_HUMAN" 9 1967.9828 0.9 57175 25366 3 1967.980884 657.0015 Tubulin beta-2B chain OS=Homo sapiens OX=9606 GN=TUBB2B PE=1 SV=1 4.31 3944.2 - 1.18E+06 - - - -0.969 - 3.892 0.705 - 745.8 1 2 0 -0.0019 18 0 0 0 5.28E+07 5.84E+07 - - - 9.7834 1 221125_WJC_METTL3_EV_vs_WT_F04.25368.25368.3 5.38E-13 20/88 R.QEDKDDLDVTELTNEDLLDQLVK.Y "sp|P42166|LAP2A_HUMAN,sp|P42167|LAP2B_HUMAN,tr|G5E972|G5E972_HUMAN,tr|H0YJH7|H0YJH7_HUMAN" 4 2687.3025 1.21 57177 25368 3 2687.301333 896.7748 "Lamina-associated polypeptide 2, isoform alpha OS=Homo sapiens OX=9606 GN=TMPO PE=1 SV=2" 3.72 3944.5 - 743883 - - - -0.4402 - 3.691 0.666 - 598.9 1 2 1 -0.0012 23 0 0 0 7.31E+07 6.06E+07 - - - 9.0285 1 221125_WJC_METTL3_EV_vs_WT_F04.25369.25369.3 1.93E-12 24/68 K.GHYTEGAELVDSVLDVVR.K "sp|Q9BVA1|TBB2B_HUMAN,sp|P07437|TBB5_HUMAN,sp|Q13509|TBB3_HUMAN,sp|Q13885|TBB2A_HUMAN,sp|P68371|TBB4B_HUMAN,tr|A0A0B4J269|A0A0B4J269_HUMAN,tr|Q5ST81|Q5ST81_HUMAN,tr|Q5JP53|Q5JP53_HUMAN,tr|G3V2A3|G3V2A3_HUMAN" 9 1957.9745 0.75 57178 25369 3 1957.974296 653.6655 Tubulin beta-2B chain OS=Homo sapiens OX=9606 GN=TUBB2B PE=1 SV=1 4.31 3944.6 - 670946 - - - -0.1149 - 4.224 0.712 - 983.5 1 2 0 -0.0002 18 0 0 0 5.99E+07 7.96E+07 - - - 10.0657 1 221125_WJC_METTL3_EV_vs_WT_F04.25375.25375.3 2.39E-16 24/88 R.QEDK[136.11]DDLDVTELTNEDLLDQLVK[136.11].Y "sp|P42166|LAP2A_HUMAN,sp|P42167|LAP2B_HUMAN,tr|G5E972|G5E972_HUMAN,tr|H0YJH7|H0YJH7_HUMAN" 4 2703.3309 1.21 57181 25375 3 2703.328637 902.1176 "Lamina-associated polypeptide 2, isoform alpha OS=Homo sapiens OX=9606 GN=TMPO PE=1 SV=2" 3.72 3945.4 - 3.33E+06 - - - -0.843 - 4.261 0.715 - 837.9 1 2 1 -0.0023 23 0 0 0 7.31E+07 6.06E+07 - - - 9.9114 1 221125_WJC_METTL3_EV_vs_WT_F04.25378.25378.3 2.16E-12 22/108 R.PHNVQPNWITLGNQLDGIHLLDPDVVAR[166.11].F sp|Q86U44|MTA70_HUMAN 1 3140.6395 0.01 57184 25378 3 3141.635448 1047.8871 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 5.14 3945.6 - 3.63E+06 - - - 317.1208 - 3.984 0.683 - 248.6 1 1 0 0.996 28 0 0 0 1.25E+07 1.00E+09 - - - 9.059 1 221125_WJC_METTL3_EV_vs_WT_F04.25382.25382.3 2.55E-13 22/88 K.NDITAWQEC[160.03]VNNSMAQLEHQAVR.L sp|O75934|SPF27_HUMAN 1 2713.2337 1.37 57186 25382 3 2713.229373 905.4185 Pre-mRNA-splicing factor SPF27 OS=Homo sapiens OX=9606 GN=BCAS2 PE=1 SV=1 4.65 3946.1 - 766400 - - - -1.5881 - 4.656 0.656 - 534.3 1 2 0 -0.0043 23 0 0 0 7.84E+06 5.73E+06 - - - 9.461 1 221125_WJC_METTL3_EV_vs_WT_F04.25383.25383.3 5.74E-05 13/116 K.ETGANLAIC[160.03]QWGFDDEANHLLLQNNLPAVR.W "sp|P48643|TCPE_HUMAN,tr|E9PCA1|E9PCA1_HUMAN,tr|B7ZAR1|B7ZAR1_HUMAN,tr|E7ENZ3|E7ENZ3_HUMAN" 4 3378.6415 0.61 57187 25383 3 3378.632707 1127.2211 T-complex protein 1 subunit epsilon OS=Homo sapiens OX=9606 GN=CCT5 PE=1 SV=1 4.31 3946.2 - 689450 - - - -2.6096 - 2.878 0.607 - 102.3 1 2 0 -0.0088 30 0 0 0 6.63E+06 1.08E+07 - - - 7.737 1 221125_WJC_METTL3_EV_vs_WT_F04.25389.25389.4 1.61E-07 27/150 R.AGTFQAFEQFGQQLLAHGHYASPEIK.Q "sp|Q13813|SPTN1_HUMAN,tr|A0A0D9SF54|A0A0D9SF54_HUMAN,tr|A0A0D9SGF6|A0A0D9SGF6_HUMAN" 3 2874.4089 1.41 57191 25389 4 2874.410107 719.6095 "Spectrin alpha chain, non-erythrocytic 1 OS=Homo sapiens OX=9606 GN=SPTAN1 PE=1 SV=3" 6.01 3946.9 - 2.35E+06 - - - 0.4102 - 5.075 0.565 - 737.4 1 2 0 0.0012 26 0 0 0 1.71E+07 1.22E+07 - - - 4.6558 1 221125_WJC_METTL3_EV_vs_WT_F04.25390.25390.3 4.84E-14 25/116 K.DMAIATGGAVFGEEGLTLNLEDVQPHDLGK.V "sp|P10809|CH60_HUMAN,tr|A0A7I2V2X6|A0A7I2V2X6_HUMAN,tr|A0A7I2YQK6|A0A7I2YQK6_HUMAN,tr|A0A7I2V599|A0A7I2V599_HUMAN" 4 3096.5074 1.46 57192 25390 3 3096.503524 1033.1764 "60 kDa heat shock protein, mitochondrial OS=Homo sapiens OX=9606 GN=HSPD1 PE=1 SV=2" 4.01 3947 - 2.01E+06 - - - -1.2456 - 4.798 0.695 - 395.5 1 2 0 -0.0039 30 0 0 0 4.91E+07 3.36E+07 - - - 9.8954 1 221125_WJC_METTL3_EV_vs_WT_F04.25391.25391.4 5.70E-07 21/150 R.AGTFQAFEQFGQQLLAHGHYASPEIK[136.11].Q "sp|Q13813|SPTN1_HUMAN,tr|A0A0D9SF54|A0A0D9SF54_HUMAN,tr|A0A0D9SGF6|A0A0D9SGF6_HUMAN" 3 2882.4231 1.41 57193 25391 4 2882.421646 721.6131 "Spectrin alpha chain, non-erythrocytic 1 OS=Homo sapiens OX=9606 GN=SPTAN1 PE=1 SV=3" 6.01 3947.1 - 1.79E+06 - - - -0.5142 - 4.199 0.549 - 336.8 1 2 0 -0.0015 26 0 0 0 1.71E+07 1.22E+07 - - - 4.4567 0.987 221125_WJC_METTL3_EV_vs_WT_F04.25395.25395.4 4.49E-07 17/102 R.K[136.11]IELFGR[166.11]PHNVQPNWITL.G sp|Q86U44|MTA70_HUMAN 1 2179.2021 0.02 57195 25395 4 2179.198777 545.8078 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 8.75 3947.5 - 4.26E+06 - - - -1.5308 - 3.162 0.409 - 148.5 1 1 0 -0.0033 18 0 0 0 5.08E+05 2.09E+07 - - - 3.1794 1 221125_WJC_METTL3_EV_vs_WT_F04.25396.25396.3 1.17E-10 24/116 K.DMAIATGGAVFGEEGLTLNLEDVQPHDLGK[136.11].V "sp|P10809|CH60_HUMAN,tr|A0A7I2V2X6|A0A7I2V2X6_HUMAN,tr|A0A7I2YQK6|A0A7I2YQK6_HUMAN,tr|A0A7I2V599|A0A7I2V599_HUMAN" 4 3104.5216 1.49 57196 25396 3 3104.514179 1035.8478 "60 kDa heat shock protein, mitochondrial OS=Homo sapiens OX=9606 GN=HSPD1 PE=1 SV=2" 4.01 3947.6 - 2.41E+06 - - - -2.3843 - 4.335 0.595 - 321.7 1 2 0 -0.0074 30 0 0 0 5.23E+07 3.51E+07 - - - 8.546 1 221125_WJC_METTL3_EV_vs_WT_F04.25406.25406.4 3.41E-11 23/132 R.AEMDMVAWGVDLASVEQHINSHR.G sp|P15924|DESP_HUMAN 1 2594.2006 31.93 57202 25406 4 2594.198222 649.5574 Desmoplakin OS=Homo sapiens OX=9606 GN=DSP PE=1 SV=3 4.72 3948.9 - 1.16E+06 - - - -0.9132 - 3.917 0.624 - 484.2 1 2 0 -0.0024 23 0 0 0 4.93E+06 1.54E+05 - - - 5.099 1 221125_WJC_METTL3_EV_vs_WT_F04.25407.25407.3 2.43E-09 15/60 K.DFGNYLFNFASAATK[136.11]K[136.11].L sp|Q96A49|SYAP1_HUMAN 1 1808.9068 1.26 57203 25407 3 1808.908371 603.9762 Synapse-associated protein 1 OS=Homo sapiens OX=9606 GN=SYAP1 PE=1 SV=1 8.5 3949 - 1.10E+06 - - - 0.8491 - 2.714 0.649 - 171.1 1 2 0 0.0015 16 0 0 0 7.52E+06 5.96E+06 - - - 8.3371 1 221125_WJC_METTL3_EV_vs_WT_F04.25408.25408.3 9.81E-11 20/60 K.DFGNYLFNFASAATKK.L sp|Q96A49|SYAP1_HUMAN 1 1792.8784 1.26 57204 25408 3 1792.876801 598.6334 Synapse-associated protein 1 OS=Homo sapiens OX=9606 GN=SYAP1 PE=1 SV=1 8.5 3949.2 - 1.07E+06 - - - -0.9114 - 3.124 0.633 - 379.7 1 2 0 -0.0016 16 0 0 0 7.52E+06 5.96E+06 - - - 8.5197 1 221125_WJC_METTL3_EV_vs_WT_F04.25414.25414.4 7.47E-11 28/132 R.TMHHLLLEVEVIEGTLQC[160.03]PESGR.M sp|Q9UI30|TR112_HUMAN 1 2647.3098 3.98 57208 25414 4 2647.308591 662.8347 Multifunctional methyltransferase subunit TRM112-like protein OS=Homo sapiens OX=9606 GN=TRMT112 PE=1 SV=1 4.87 3949.9 - 1.35E+06 - - - -0.4593 - 4.424 0.519 - 635 1 2 0 -0.0012 23 0 0 0 6.04E+07 1.52E+07 - - - 4.2248 0.9999 221125_WJC_METTL3_EV_vs_WT_F04.25415.25415.4 3.51E-09 16/132 K.LVLEHSKDDDNLDSLLDSVVGLK.Q "sp|Q69YN4|VIR_HUMAN,tr|H0YB68|H0YB68_HUMAN" 2 2523.3068 0.49 57209 25415 4 2523.306464 631.834 Protein virilizer homolog OS=Homo sapiens OX=9606 GN=VIRMA PE=1 SV=2 4.17 3950.1 - 1.42E+06 - - - -0.1387 - 2.646 0.549 - 165.8 1 2 1 -0.0003 23 0 0 0 5.33E+06 1.08E+07 - - - 4.3197 1 221125_WJC_METTL3_EV_vs_WT_F04.25420.25420.3 5.59E-11 25/88 R.TMHHLLLEVEVIEGTLQC[160.03]PESGR.M sp|Q9UI30|TR112_HUMAN 1 2647.3098 1.36 57212 25420 3 2647.314056 883.4439 Multifunctional methyltransferase subunit TRM112-like protein OS=Homo sapiens OX=9606 GN=TRMT112 PE=1 SV=1 4.87 3950.7 - 825113 - - - 1.605 - 4.894 0.559 - 984.7 1 2 0 0.0042 23 0 0 0 1.03E+07 7.53E+06 - - - 8.4965 1 221125_WJC_METTL3_EV_vs_WT_F04.25421.25421.4 2.45E-09 26/192 R.QQELTALYQMQHLQYQQFLIQQQYAQVLAQQQK.A "sp|Q6Y7W6|GGYF2_HUMAN,tr|A0A7I2V3H7|A0A7I2V3H7_HUMAN,tr|I1E4Y6|I1E4Y6_HUMAN,tr|A0A7I2V516|A0A7I2V516_HUMAN,tr|A0A7I2V3H0|A0A7I2V3H0_HUMAN,tr|C9JHW1|C9JHW1_HUMAN,tr|A0A7I2V361|A0A7I2V361_HUMAN,tr|E7ESB6|E7ESB6_HUMAN" 8 4064.0578 3.3 57213 25421 4 4064.056807 1017.0217 GRB10-interacting GYF protein 2 OS=Homo sapiens OX=9606 GN=GIGYF2 PE=1 SV=1 6.75 3950.9 - 1.23E+06 - - - -0.2495 - 3.868 0.551 - 357.9 1 2 0 -0.001 33 0 0 0 9.81E+06 2.97E+06 - - - 4.4275 1 221125_WJC_METTL3_EV_vs_WT_F04.25422.25422.2 0.000384 21/30 K.K[136.11]VSQEILELLNTTTAK[136.11].E "sp|Q86U44|MTA70_HUMAN,tr|H0YFV6|H0YFV6_HUMAN" 2 1803.0324 0.001 57214 25422 2 1803.033055 902.5235 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 6.14 3951 - 694959 - - - 0.3466 - 4.221 0.701 - 1266.9 1 2 0 0.0006 16 0 0 0 0.00E+00 1.58E+07 - - - 7.7589 0.9595 221125_WJC_METTL3_EV_vs_WT_F04.25428.25428.3 5.20E-09 22/104 T.DAVSIC[160.03]LAISTPDAPATQDGVESLLQK[136.11].F "sp|Q86U44|MTA70_HUMAN,tr|B4E349|B4E349_HUMAN,tr|F5H6D8|F5H6D8_HUMAN,tr|H0YFV6|H0YFV6_HUMAN,tr|B4DTN4|B4DTN4_HUMAN" 5 2806.415 0.02 57218 25428 3 2807.420568 936.4789 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 3.84 3951.8 - 605757 - - - 358.3137 - 4.13 0.551 - 601.5 1 1 0 1.0056 27 0 0 0 1.77E+05 1.06E+07 - - - 7.6675 1 221125_WJC_METTL3_EV_vs_WT_F04.25430.25430.2 7.88E-11 17/40 K.DDGVSIPGEYTSFLAPISSSK.L "sp|O14744|ANM5_HUMAN,tr|H0YJD3|H0YJD3_HUMAN,tr|H7BZ44|H7BZ44_HUMAN" 3 2169.0477 3.89 57220 25430 2 2169.048572 1085.5311 Protein arginine N-methyltransferase 5 OS=Homo sapiens OX=9606 GN=PRMT5 PE=1 SV=4 4.03 3952 - 438866 - - - 0.3813 - 2.84 0.681 - 555.3 1 2 0 0.0008 21 0 0 0 7.24E+06 1.86E+06 - - - 6.6368 1 221125_WJC_METTL3_EV_vs_WT_F04.25437.25437.3 1.81E-15 25/108 K.NIILEEGK[136.11]EILVGDVGQTVDDPYATFVK[136.11].M "sp|P23528|COF1_HUMAN,tr|E9PP50|E9PP50_HUMAN,tr|G3V1A4|G3V1A4_HUMAN,tr|E9PQB7|E9PQB7_HUMAN,tr|E9PK25|E9PK25_HUMAN,tr|E9PLJ3|E9PLJ3_HUMAN,tr|E9PS23|E9PS23_HUMAN" 7 3077.6143 2.54 57225 25437 3 3077.614111 1026.8787 Cofilin-1 OS=Homo sapiens OX=9606 GN=CFL1 PE=1 SV=3 4.02 3953 - 633237 - - - -0.0773 - 4.143 0.68 - 537.7 1 2 1 -0.0002 28 0 0 0 1.11E+07 4.36E+06 - - - 9.3914 1 221125_WJC_METTL3_EV_vs_WT_F04.25438.25438.3 1.42E-12 19/128 K.AQDEIPALSVSRPQTGLSFLGPEPEDLEDLYSR.Y sp|P43686|PRS6B_HUMAN 1 3628.7897 1.09 57226 25438 3 3628.788279 1210.6038 26S proteasome regulatory subunit 6B OS=Homo sapiens OX=9606 GN=PSMC4 PE=1 SV=2 3.95 3953.1 - 504066 - - - -0.388 - 3.302 0.715 - 153.3 1 2 0 -0.0014 33 0 0 0 2.18E+06 2.00E+06 - - - 9.2593 1 221125_WJC_METTL3_EV_vs_WT_F04.25443.25443.3 8.91E-12 21/60 R.THNLEPYFESFINNLR.R sp|P04264|K2C1_HUMAN 1 1992.9694 10576.47 57229 25443 3 1992.966682 665.3304 "Keratin, type II cytoskeletal 1 OS=Homo sapiens OX=9606 GN=KRT1 PE=1 SV=6" 5.37 3953.8 - 5.98E+06 - - - -1.3518 - 3.589 0.667 - 866.8 1 2 0 -0.0027 16 0 0 0 1.18E+09 1.12E+05 - - - 9.2545 0.9643 221125_WJC_METTL3_EV_vs_WT_F04.25445.25445.3 0.00475 16/76 K.K[136.11]LLHHLSDLALTLPTDAVSI.C "sp|Q86U44|MTA70_HUMAN,tr|B4E349|B4E349_HUMAN,tr|F5H6D8|F5H6D8_HUMAN,tr|H0YFV6|H0YFV6_HUMAN,tr|B4DTN4|B4DTN4_HUMAN" 5 2164.2347 0.001 57231 25445 3 2164.227036 722.4188 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 5.98 3954 - 1.10E+06 - - - -3.5435 - 2.925 0.405 - 214.9 1 1 0 -0.0077 20 0 0 0 0.00E+00 6.63E+06 - - - 5.6571 1 221125_WJC_METTL3_EV_vs_WT_F04.25455.25455.2 1.83E-10 15/30 R.THNLEPYFESFINNLR.R sp|P04264|K2C1_HUMAN 1 1992.9694 24.11 57234 25455 2 1992.963665 997.492 "Keratin, type II cytoskeletal 1 OS=Homo sapiens OX=9606 GN=KRT1 PE=1 SV=6" 5.37 3955.6 - 1.42E+06 - - - -2.8656 - 3.002 0.663 - 468.4 1 2 0 -0.0057 16 0 0 0 6.37E+07 2.64E+06 - - - 6.6388 1 221125_WJC_METTL3_EV_vs_WT_F04.25459.25459.3 1.70E-11 25/100 R.SESGGLGVSMVEYVLSSSPGDSC[160.03]LRK.G "sp|Q14671|PUM1_HUMAN,tr|Q5T1Z8|Q5T1Z8_HUMAN,tr|H0YEH2|H0YEH2_HUMAN,tr|Q5T1Z4|Q5T1Z4_HUMAN" 4 2700.2735 2.7 57236 25459 3 2700.265427 901.0984 Pumilio homolog 1 OS=Homo sapiens OX=9606 GN=PUM1 PE=1 SV=3 4.68 3956.1 - 1.09E+06 - - - -2.983 - 4.122 0.653 - 518.6 1 2 0 -0.0081 26 0 0 0 1.46E+07 5.40E+06 - - - 9.0766 1 221125_WJC_METTL3_EV_vs_WT_F04.25460.25460.3 1.05E-14 26/76 R.NK[136.11]NPAPPIDAVEQILPTLVR[166.11].L "sp|P52292|IMA1_HUMAN,tr|A0A7I2V3Z3|A0A7I2V3Z3_HUMAN,tr|A0A7I2YQE1|A0A7I2YQE1_HUMAN,tr|A0A7I2V487|A0A7I2V487_HUMAN,tr|A0A7I2V351|A0A7I2V351_HUMAN" 5 2202.2491 1.43 57237 25460 3 2202.249069 735.0903 Importin subunit alpha-1 OS=Homo sapiens OX=9606 GN=KPNA2 PE=1 SV=1 6.07 3956.2 - 1.06E+06 - - - -0.0245 - 4.539 0.681 - 633.4 1 2 1 -0.0001 20 0 0 0 1.16E+08 8.13E+07 - - - 9.8023 1 221125_WJC_METTL3_EV_vs_WT_F04.25465.25465.3 1.25E-16 28/76 R.NKNPAPPIDAVEQILPTLVR.L "sp|P52292|IMA1_HUMAN,tr|A0A7I2V3Z3|A0A7I2V3Z3_HUMAN,tr|A0A7I2YQE1|A0A7I2YQE1_HUMAN,tr|A0A7I2V487|A0A7I2V487_HUMAN,tr|A0A7I2V351|A0A7I2V351_HUMAN" 5 2184.2267 1.44 57240 25465 3 2184.225138 729.0828 Importin subunit alpha-1 OS=Homo sapiens OX=9606 GN=KPNA2 PE=1 SV=1 6.07 3956.9 - 2.36E+06 - - - -0.6936 - 4.186 0.719 - 839.7 1 2 1 -0.0015 20 0 0 0 1.17E+08 8.13E+07 - - - 10.0292 1 221125_WJC_METTL3_EV_vs_WT_F04.25466.25466.3 1.10E-19 27/92 K.HYQEEGQGTEVVQGVLLGLVVEDR.L "sp|O15372|EIF3H_HUMAN,tr|B3KS98|B3KS98_HUMAN,tr|A0A087WZK9|A0A087WZK9_HUMAN,tr|E5RFW7|E5RFW7_HUMAN,tr|E5RFH0|E5RFH0_HUMAN,tr|E5RGU4|E5RGU4_HUMAN" 6 2653.3348 1.74 57241 25466 3 2653.327985 885.4522 Eukaryotic translation initiation factor 3 subunit H OS=Homo sapiens OX=9606 GN=EIF3H PE=1 SV=1 4.25 3957 - 1.10E+06 - - - -2.5534 - 4.827 0.738 - 760.3 1 2 0 -0.0068 24 0 0 0 1.12E+08 6.44E+07 - - - 10.4224 1 221125_WJC_METTL3_EV_vs_WT_F04.25473.25473.4 3.00E-12 27/162 R.DKLDGNELDLSLSDLNEVPVKELAALPK.A sp|Q96AG4|LRC59_HUMAN 1 3034.6074 1.64 57243 25473 4 3034.613444 759.6591 Leucine-rich repeat-containing protein 59 OS=Homo sapiens OX=9606 GN=LRRC59 PE=1 SV=1 4.14 3958 - 1.46E+06 - - - 1.9877 - 4.308 0.697 - 340.4 1 2 2 0.006 28 0 0 0 9.94E+06 6.06E+06 - - - 5.7445 1 221125_WJC_METTL3_EV_vs_WT_F04.25478.25478.4 1.48E-10 22/90 R.THNLEPYFESFINNLR.R sp|P04264|K2C1_HUMAN 1 1992.9694 999 57246 25478 4 1992.96881 499.2496 "Keratin, type II cytoskeletal 1 OS=Homo sapiens OX=9606 GN=KRT1 PE=1 SV=6" 5.37 3958.6 - 1.31E+06 - - - -0.284 - 3.924 0.677 - 484 1 2 0 -0.0006 16 0 0 0 2.36E+07 0.00E+00 - - - 5.6 1 221125_WJC_METTL3_EV_vs_WT_F04.25493.25493.3 2.93E-08 29/84 R.K[136.11]PLVIIAEDVDGEALSTLVLNR[166.11].L "sp|P10809|CH60_HUMAN,tr|A0A7I2V2X6|A0A7I2V2X6_HUMAN,tr|A0A7I2YQK6|A0A7I2YQK6_HUMAN,tr|A0A7I2V599|A0A7I2V599_HUMAN,tr|A0A7I2YQ71|A0A7I2YQ71_HUMAN,tr|A0A7I2V5M1|A0A7I2V5M1_HUMAN,tr|A0A7I2V5K3|A0A7I2V5K3_HUMAN" 7 2382.3489 1.21 57253 25493 3 2382.346593 795.1236 "60 kDa heat shock protein, mitochondrial OS=Homo sapiens OX=9606 GN=HSPD1 PE=1 SV=2" 4.32 3960.6 - 1.41E+06 - - - -0.9671 - 5.299 0.658 - 1056.2 1 2 0 -0.0023 22 0 0 0 6.84E+07 5.67E+07 - - - 9.8288 1 221125_WJC_METTL3_EV_vs_WT_F04.25502.25502.3 9.27E-11 Nov-84 R.DNYVPEVSALDQEIIEVDPDTK.E "sp|P08708|RS17_HUMAN,tr|H3BNC9|H3BNC9_HUMAN,tr|H0YN88|H0YN88_HUMAN,tr|A0A075B716|A0A075B716_HUMAN" 4 2488.1857 2.43 57260 25502 3 2488.185403 830.4025 40S ribosomal protein S17 OS=Homo sapiens OX=9606 GN=RPS17 PE=1 SV=2 3.62 3961.7 - 1.27E+06 - - - -0.1174 - 2.902 0.67 - 72.5 1 2 0 -0.0003 22 0 0 0 2.45E+07 1.01E+07 - - - 8.5356 1 221125_WJC_METTL3_EV_vs_WT_F04.25505.25505.3 9.43E-08 13/76 R.K[136.11]LPIDVTEGEVISLGLPFGK[136.11].V "sp|P26599|PTBP1_HUMAN,tr|A0A6Q8PEX4|A0A6Q8PEX4_HUMAN,tr|A0A0U1RRM4|A0A0U1RRM4_HUMAN,tr|A6NLN1|A6NLN1_HUMAN,tr|K7EKJ7|K7EKJ7_HUMAN,tr|K7ELW5|K7ELW5_HUMAN,tr|K7ES59|K7ES59_HUMAN,tr|A0A7I2V4H6|A0A7I2V4H6_HUMAN,tr|A0A7I2V621|A0A7I2V621_HUMAN" 9 2127.2162 1.86 57263 25505 3 2127.214283 710.0793 Polypyrimidine tract-binding protein 1 OS=Homo sapiens OX=9606 GN=PTBP1 PE=1 SV=1 4.68 3962.1 - 400770 - - - -0.9049 - 2.943 0.602 - 155 1 2 0 -0.0019 20 0 0 0 4.79E+06 2.58E+06 - - - 7.8699 1 221125_WJC_METTL3_EV_vs_WT_F04.25506.25506.3 0.00307 17/64 K.SVQNDSQAIAEVLNQLK.D sp|P15924|DESP_HUMAN 1 1855.964 12.12 57264 25506 3 1855.961559 619.6619 Desmoplakin OS=Homo sapiens OX=9606 GN=DSP PE=1 SV=3 4.37 3962.2 - 399642 - - - -1.2915 - 3.324 0.546 - 464.8 1 2 0 -0.0024 17 0 0 0 3.72E+06 3.07E+05 - - - 7.6612 1 221125_WJC_METTL3_EV_vs_WT_F04.25510.25510.3 3.90E-10 19/80 K.NQILNLTTDNANILLQIDNAR.L "sp|P13645|K1C10_HUMAN,tr|A0A1B0GVI3|A0A1B0GVI3_HUMAN" 2 2366.2554 88.6 57266 25510 3 2366.245949 789.7591 "Keratin, type I cytoskeletal 10 OS=Homo sapiens OX=9606 GN=KRT10 PE=1 SV=6" 4.21 3962.8 - 5.24E+06 - - - -3.9886 - 3.64 0.616 - 406.5 1 2 0 -0.0094 21 0 0 0 9.90E+06 1.12E+05 - - - 8.5026 1 221125_WJC_METTL3_EV_vs_WT_F04.25513.25513.3 1.05E-07 13/76 R.KLPIDVTEGEVISLGLPFGK.V "sp|P26599|PTBP1_HUMAN,tr|A0A6Q8PEX4|A0A6Q8PEX4_HUMAN,tr|A0A0U1RRM4|A0A0U1RRM4_HUMAN,tr|A6NLN1|A6NLN1_HUMAN,tr|K7EKJ7|K7EKJ7_HUMAN,tr|K7ELW5|K7ELW5_HUMAN,tr|K7ES59|K7ES59_HUMAN,tr|A0A7I2V4H6|A0A7I2V4H6_HUMAN,tr|A0A7I2V621|A0A7I2V621_HUMAN" 9 2111.1878 1.45 57269 25513 3 2111.187532 704.7365 Polypyrimidine tract-binding protein 1 OS=Homo sapiens OX=9606 GN=PTBP1 PE=1 SV=1 4.68 3963.2 - 650747 - - - -0.1307 - 3.063 0.547 - 141.3 1 2 0 -0.0003 20 0 0 0 3.75E+06 2.58E+06 - - - 7.3541 1 221125_WJC_METTL3_EV_vs_WT_F04.25514.25514.4 2.41E-09 17/126 R.K[136.11]PLVIIAEDVDGEALSTLVLNR[166.11].L "sp|P10809|CH60_HUMAN,tr|A0A7I2V2X6|A0A7I2V2X6_HUMAN,tr|A0A7I2YQK6|A0A7I2YQK6_HUMAN,tr|A0A7I2V599|A0A7I2V599_HUMAN,tr|A0A7I2YQ71|A0A7I2YQ71_HUMAN,tr|A0A7I2V5M1|A0A7I2V5M1_HUMAN,tr|A0A7I2V5K3|A0A7I2V5K3_HUMAN" 7 2382.3489 1.54 57270 25514 4 2382.349009 596.5945 "60 kDa heat shock protein, mitochondrial OS=Homo sapiens OX=9606 GN=HSPD1 PE=1 SV=2" 4.32 3963.3 - 566035 - - - 0.047 - 3.424 0.667 - 256.3 1 2 0 0.0001 22 0 0 0 6.34E+06 4.12E+06 - - - 5.4343 1 221125_WJC_METTL3_EV_vs_WT_F04.25518.25518.4 0.000232 15/96 R.TFHIFYYLLSGAGEHLK[136.11].T sp|P35579|MYH9_HUMAN 1 2003.0396 0.89 57274 25518 4 2003.040716 501.7672 Myosin-9 OS=Homo sapiens OX=9606 GN=MYH9 PE=1 SV=4 6.61 3963.8 - 439909 - - - 0.5402 - 2.543 0.5 - 141.3 1 2 0 0.0011 17 0 0 0 9.83E+05 1.11E+06 - - - 3.9018 0.9999 221125_WJC_METTL3_EV_vs_WT_F04.25519.25519.4 1.80E-05 10/192 K.VLYLGAASGTTVSHVSDIVGPDGLVYAVEFSHR.S "sp|P22087|FBRL_HUMAN,tr|M0R299|M0R299_HUMAN,tr|M0R0P1|M0R0P1_HUMAN,tr|M0QXL5|M0QXL5_HUMAN,tr|M0R2Q4|M0R2Q4_HUMAN" 5 3415.7412 0.53 57275 25519 4 3415.741772 854.9426 rRNA 2'-O-methyltransferase fibrillarin OS=Homo sapiens OX=9606 GN=FBL PE=1 SV=2 5.21 3963.9 - 434120 - - - 0.1613 - 2.128 0.478 - 37.2 1 2 0 0.0006 33 0 0 0 1.71E+06 3.22E+06 - - - 3.6129 0.9573 221125_WJC_METTL3_EV_vs_WT_F04.25522.25522.2 0.0024 16-Jul K.GVLGHLK[136.11]AR[166.11].L "sp|Q96NB1|CEP20_HUMAN,tr|I3NI25|I3NI25_HUMAN,tr|I3L4V2|I3L4V2_HUMAN,tr|I3L3N6|I3L3N6_HUMAN,tr|I3L0K3|I3L0K3_HUMAN,tr|I3L2N4|I3L2N4_HUMAN" 6 967.6046 0.001 57278 25522 2 967.605834 484.8096 Centrosomal protein 20 OS=Homo sapiens OX=9606 GN=CEP20 PE=1 SV=1 11 3964.3 - 174607 - - - 1.2712 - 1.448 0.199 - 102.4 1 2 1 0.0012 9 0 0 0 0.00E+00 1.19E+06 - - - 1.5814 1 221125_WJC_METTL3_EV_vs_WT_F04.25527.25527.3 6.37E-18 29/84 R.KPLVIIAEDVDGEALSTLVLNR.L "sp|P10809|CH60_HUMAN,tr|A0A7I2V2X6|A0A7I2V2X6_HUMAN,tr|A0A7I2YQK6|A0A7I2YQK6_HUMAN,tr|A0A7I2V599|A0A7I2V599_HUMAN,tr|A0A7I2YQ71|A0A7I2YQ71_HUMAN,tr|A0A7I2V5M1|A0A7I2V5M1_HUMAN,tr|A0A7I2V5K3|A0A7I2V5K3_HUMAN" 7 2364.3264 1.21 57281 25527 3 2364.324786 789.1161 "60 kDa heat shock protein, mitochondrial OS=Homo sapiens OX=9606 GN=HSPD1 PE=1 SV=2" 4.32 3964.9 - 7.45E+06 - - - -0.6941 - 5.19 0.62 - 1094.6 1 2 0 -0.0016 22 0 0 0 6.84E+07 5.67E+07 - - - 9.3561 1 221125_WJC_METTL3_EV_vs_WT_F04.25530.25530.3 8.15E-12 19/108 R.SNPENNVGLITLANDC[160.03]EVLTTLTPDTGR.L "sp|P55036|PSMD4_HUMAN,tr|A6PVX3|A6PVX3_HUMAN,tr|Q5VWC4|Q5VWC4_HUMAN" 3 3013.4662 2.46 57284 25530 3 3013.462731 1005.496 26S proteasome non-ATPase regulatory subunit 4 OS=Homo sapiens OX=9606 GN=PSMD4 PE=1 SV=1 3.92 3965.2 - 1.27E+06 - - - -1.1658 - 3.202 0.678 - 284.8 1 2 0 -0.0035 28 0 0 0 6.19E+06 2.52E+06 - - - 8.7755 0.999 221125_WJC_METTL3_EV_vs_WT_F04.25535.25535.2 1.65E-08 Sep-42 R.DNYVPEVSALDQEIIEVDPDTK[136.11].E "sp|P08708|RS17_HUMAN,tr|H3BNC9|H3BNC9_HUMAN,tr|H0YN88|H0YN88_HUMAN,tr|A0A075B716|A0A075B716_HUMAN" 4 2496.1999 -1 57289 25535 2 2496.189729 1249.1072 40S ribosomal protein S17 OS=Homo sapiens OX=9606 GN=RPS17 PE=1 SV=2 3.62 3965.9 - 247965 - - - -4.0726 - 2.26 0.563 - 99 1 2 0 -0.0102 22 0 0 0 0.00E+00 0.00E+00 - - - 5.2007 1 221125_WJC_METTL3_EV_vs_WT_F04.25540.25540.3 3.80E-14 20/100 R.TDC[160.03]SPIQFESAWALTNIASGTSEQTK.A "sp|P52292|IMA1_HUMAN,tr|A0A7I2V3Z3|A0A7I2V3Z3_HUMAN,tr|A0A7I2YQE1|A0A7I2YQE1_HUMAN,tr|A0A7I2V487|A0A7I2V487_HUMAN,tr|A0A7I2V351|A0A7I2V351_HUMAN" 5 2841.3127 1.57 57293 25540 3 2841.308959 948.1115 Importin subunit alpha-1 OS=Homo sapiens OX=9606 GN=KPNA2 PE=1 SV=1 4.14 3966.4 - 1.49E+06 - - - -1.3181 - 3.987 0.668 - 283.5 1 2 0 -0.0037 26 0 0 0 9.84E+06 6.25E+06 - - - 9.1684 1 221125_WJC_METTL3_EV_vs_WT_F04.25542.25542.4 1.19E-06 18/126 R.KPLVIIAEDVDGEALSTLVLNR.L "sp|P10809|CH60_HUMAN,tr|A0A7I2V2X6|A0A7I2V2X6_HUMAN,tr|A0A7I2YQK6|A0A7I2YQK6_HUMAN,tr|A0A7I2V599|A0A7I2V599_HUMAN,tr|A0A7I2YQ71|A0A7I2YQ71_HUMAN,tr|A0A7I2V5M1|A0A7I2V5M1_HUMAN,tr|A0A7I2V5K3|A0A7I2V5K3_HUMAN" 7 2364.3264 1.54 57295 25542 4 2364.322404 592.0889 "60 kDa heat shock protein, mitochondrial OS=Homo sapiens OX=9606 GN=HSPD1 PE=1 SV=2" 4.32 3966.7 - 1.05E+06 - - - -1.7015 - 3.592 0.571 - 273.1 1 2 0 -0.004 22 0 0 0 6.34E+06 4.12E+06 - - - 4.6133 0.9986 221125_WJC_METTL3_EV_vs_WT_F04.25545.25545.3 0.0105 13/44 R.SLDLDSIIAEVK.A sp|P04264|K2C1_HUMAN 1 1301.7078 -1 57298 25545 3 1301.703274 434.9099 "Keratin, type II cytoskeletal 1 OS=Homo sapiens OX=9606 GN=KRT1 PE=1 SV=6" 4.03 3967.1 - 363442 - - - -3.5138 - 2.088 0.338 - 293.1 1 2 0 -0.0046 12 0 0 0 0.00E+00 0.00E+00 - - - 4.3478 0.9978 221125_WJC_METTL3_EV_vs_WT_F04.25550.25550.4 0.000143 21/162 K.FAVVMADPPWDIHMELPYGTLTDDEMR[166.11]R[166.11].L sp|Q86U44|MTA70_HUMAN 1 3324.5521 0.05 57301 25550 4 3324.533882 832.1453 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 4.23 3967.7 - 1.18E+06 - - - -5.4699 - 2.764 0.408 - 141.8 1 2 0 -0.0182 28 0 0 0 1.24E+05 2.57E+06 - - - 3.0879 1 221125_WJC_METTL3_EV_vs_WT_F04.25571.25571.4 1.32E-08 35/174 K.IVKPNGEKPDEFESGISQALLELEMNSDLK.A "sp|P62081|RS7_HUMAN,tr|B5MCP9|B5MCP9_HUMAN,tr|A0A2R8Y623|A0A2R8Y623_HUMAN" 3 3329.6701 0.86 57309 25571 4 3329.666418 833.4248 40S ribosomal protein S7 OS=Homo sapiens OX=9606 GN=RPS7 PE=1 SV=1 4.25 3970.6 - 2.85E+06 - - - -1.1025 - 5.305 0.643 - 878 1 2 0 -0.0037 30 0 0 0 1.11E+08 1.29E+08 - - - 5.3323 1 221125_WJC_METTL3_EV_vs_WT_F04.25572.25572.4 1.23E-16 36/210 R.LC[160.03]C[160.03]QEDPELDSDKDETGAYLIDRDPTYFGPILNYLR.H sp|Q14681|KCTD2_HUMAN 1 4290.9726 15.68 57310 25572 4 4290.970328 1073.7504 BTB\POZ domain-containing protein KCTD2 OS=Homo sapiens OX=9606 GN=KCTD2 PE=1 SV=3 3.93 3970.7 - 2.54E+06 - - - -0.5192 - 4.976 0.758 - 433.3 1 2 2 -0.0022 36 0 0 0 3.57E+07 2.28E+06 - - - 6.296 1 221125_WJC_METTL3_EV_vs_WT_F04.25574.25574.4 2.26E-13 32/174 K.IVK[136.11]PNGEK[136.11]PDEFESGISQALLELEMNSDLK[136.11].A "sp|P62081|RS7_HUMAN,tr|B5MCP9|B5MCP9_HUMAN,tr|A0A2R8Y623|A0A2R8Y623_HUMAN" 3 3353.7127 0.86 57312 25574 4 3353.708704 839.4354 40S ribosomal protein S7 OS=Homo sapiens OX=9606 GN=RPS7 PE=1 SV=1 4.25 3971 - 3.34E+06 - - - -1.1882 - 5.181 0.605 - 636.5 1 2 0 -0.004 30 0 0 0 1.11E+08 1.29E+08 - - - 4.9942 1 221125_WJC_METTL3_EV_vs_WT_F04.25577.25577.2 2.49E-06 Jun-38 K.DIENQYETQITQIEHEVSSS.G "sp|P35527|K1C9_HUMAN,tr|K7EQQ3|K7EQQ3_HUMAN" 2 2349.0608 - 57313 25577 2 2349.054933 1175.5377 "Keratin, type I cytoskeletal 9 OS=Homo sapiens OX=9606 GN=KRT9 PE=1 SV=3" 3.9 3971.4 - 399808 - - - -2.5099 - 2.334 0.673 - 64.9 1 1 0 -0.0059 20 0 0 0 - - - - - 6.0937 1 221125_WJC_METTL3_EV_vs_WT_F04.25581.25581.3 3.50E-10 16/92 K.DSEDNPQTLLFSATC[160.03]PHWVFNVAK.K sp|Q9NR30|DDX21_HUMAN 1 2775.2963 0.6 57314 25581 3 2775.291392 926.106 Nucleolar RNA helicase 2 OS=Homo sapiens OX=9606 GN=DDX21 PE=1 SV=5 4.54 3971.8 - 510286 - - - -1.7562 - 3.794 0.677 - 253.2 1 2 0 -0.0049 24 0 0 0 4.94E+06 8.18E+06 - - - 9.1835 1 221125_WJC_METTL3_EV_vs_WT_F04.25583.25583.3 1.92E-07 13/60 K.K[136.11]VSQEILELLNTTTAK[136.11].E "sp|Q86U44|MTA70_HUMAN,tr|H0YFV6|H0YFV6_HUMAN" 2 1803.0324 0 57315 25583 3 1803.028779 602.0181 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 6.14 3972 - 1.39E+06 - - - -2.0249 - 3.118 0.567 - 258.5 1 2 0 -0.0037 16 0 0 0 9.01E+04 4.61E+07 - - - 7.7784 1 221125_WJC_METTL3_EV_vs_WT_F04.25584.25584.3 3.21E-11 17/116 K.IVK[136.11]PNGEK[136.11]PDEFESGISQALLELEMNSDLK[136.11].A "sp|P62081|RS7_HUMAN,tr|B5MCP9|B5MCP9_HUMAN,tr|A0A2R8Y623|A0A2R8Y623_HUMAN" 3 3353.7127 1.03 57316 25584 3 3353.704438 1118.9115 40S ribosomal protein S7 OS=Homo sapiens OX=9606 GN=RPS7 PE=1 SV=1 4.25 3972.1 - 1.13E+06 - - - -2.4603 - 4.453 0.658 - 251.8 1 2 0 -0.0083 30 0 0 0 1.18E+07 1.15E+07 - - - 9.3099 1 221125_WJC_METTL3_EV_vs_WT_F04.25588.25588.3 1.08E-10 17/68 R.GDADQASNILASFGLSAR.D "sp|P43243|MATR3_HUMAN,tr|A8MXP9|A8MXP9_HUMAN,tr|D6R991|D6R991_HUMAN,tr|A0A0R4J2E8|A0A0R4J2E8_HUMAN,tr|D6REM6|D6REM6_HUMAN" 5 1791.8751 1.38 57318 25588 3 1791.877873 598.299 Matrin-3 OS=Homo sapiens OX=9606 GN=MATR3 PE=1 SV=2 4.21 3972.7 - 634600 - - - 1.5247 - 3.06 0.609 - 398.6 1 2 0 0.0027 18 0 0 0 3.86E+07 2.79E+07 - - - 8.114 1 221125_WJC_METTL3_EV_vs_WT_F04.25589.25589.3 2.18E-06 16/68 R.GGHPPAIQSLINLLADNR[166.11].Y sp|Q9HCD5|NCOA5_HUMAN 1 1895.0253 2.22 57319 25589 3 1895.027211 632.6824 Nuclear receptor coactivator 5 OS=Homo sapiens OX=9606 GN=NCOA5 PE=1 SV=2 6.74 3972.8 - 429997 - - - 1.0269 - 3.473 0.537 - 309.6 1 2 0 0.0019 18 0 0 0 6.16E+07 2.77E+07 - - - 7.6267 0.9997 221125_WJC_METTL3_EV_vs_WT_F04.25591.25591.4 4.28E-05 8/102 K.VFLENVIRDAVTYTEHAK.R sp|P62805|H4_HUMAN 1 2104.0953 0.87 57321 25591 4 2104.094007 527.0311 Histone H4 OS=Homo sapiens OX=9606 GN=H4C1 PE=1 SV=2 5.44 3973 - 105697 - - - -0.6164 - 1.894 0.451 - 41.7 1 2 1 -0.0013 18 0 0 0 1.30E+06 1.49E+06 - - - 3.3699 1 221125_WJC_METTL3_EV_vs_WT_F04.25594.25594.3 4.53E-13 28/116 K.IVKPNGEKPDEFESGISQALLELEMNSDLK.A "sp|P62081|RS7_HUMAN,tr|B5MCP9|B5MCP9_HUMAN,tr|A0A2R8Y623|A0A2R8Y623_HUMAN" 3 3329.6701 1.03 57322 25594 3 3329.670629 1110.8973 40S ribosomal protein S7 OS=Homo sapiens OX=9606 GN=RPS7 PE=1 SV=1 4.25 3973.5 - 1.20E+06 - - - 0.1622 - 5.037 0.717 - 684.5 1 2 0 0.0005 30 0 0 0 1.18E+07 1.15E+07 - - - 10.2534 0.9928 221125_WJC_METTL3_EV_vs_WT_F04.25595.25595.3 1.30E-05 Oct-56 K.STSESFIQHIVSLVH.H "sp|Q9NYF8|BCLF1_HUMAN,tr|E9PKI6|E9PKI6_HUMAN,tr|A0A1W2PQ43|A0A1W2PQ43_HUMAN,tr|E9PK91|E9PK91_HUMAN,tr|E9PJA7|E9PJA7_HUMAN,tr|E9PK09|E9PK09_HUMAN,tr|E9PQN2|E9PQN2_HUMAN" 7 1682.8628 - 57323 25595 3 1682.863769 561.9615 Bcl-2-associated transcription factor 1 OS=Homo sapiens OX=9606 GN=BCLAF1 PE=1 SV=2 5.93 3973.6 - 479177 - - - 0.5847 - 2.178 0.448 - 91.8 1 1 0 0.001 15 0 0 0 - - - - - 5.5656 1 221125_WJC_METTL3_EV_vs_WT_F04.25596.25596.3 9.09E-08 18/68 R.GDADQASNILASFGLSAR[166.11].D "sp|P43243|MATR3_HUMAN,tr|A8MXP9|A8MXP9_HUMAN,tr|D6R991|D6R991_HUMAN,tr|A0A0R4J2E8|A0A0R4J2E8_HUMAN,tr|D6REM6|D6REM6_HUMAN" 5 1801.8834 1.38 57324 25596 3 1801.884041 601.6351 Matrin-3 OS=Homo sapiens OX=9606 GN=MATR3 PE=1 SV=2 4.21 3973.7 - 1.59E+06 - - - 0.3496 - 3.093 0.569 - 392.4 1 2 0 0.0006 18 0 0 0 3.86E+07 2.79E+07 - - - 7.6953 0.9999 221125_WJC_METTL3_EV_vs_WT_F04.25597.25597.2 1.70E-05 24-Oct R.FSGSGSGTDFTLK.L "sp|A2NJV5|KV229_HUMAN,sp|A0A087WW87|KV240_HUMAN,sp|P06310|KV230_HUMAN,sp|A0A075B6S2|KVD29_HUMAN,sp|P01614|KVD40_HUMAN,sp|P01615|KVD28_HUMAN,sp|A0A075B6S6|KVD30_HUMAN,sp|A0A075B6P5|KV228_HUMAN,sp|A0A0A0MRZ7|KVD26_HUMAN" 9 1302.6092 999 57325 25597 2 1302.610592 652.3119 Immunoglobulin kappa variable 2-29 OS=Homo sapiens OX=9606 GN=IGKV2-29 PE=3 SV=2 5.84 3973.8 - 597014 - - - 1.0717 - 2.199 0.567 - 175.8 1 2 0 0.0014 13 0 0 0 1.63E+07 0.00E+00 - - - 5.2509 1 221125_WJC_METTL3_EV_vs_WT_F04.25604.25604.2 2.66E-12 22/34 R.GDADQASNILASFGLSAR.D "sp|P43243|MATR3_HUMAN,tr|A8MXP9|A8MXP9_HUMAN,tr|D6R991|D6R991_HUMAN,tr|A0A0R4J2E8|A0A0R4J2E8_HUMAN,tr|D6REM6|D6REM6_HUMAN" 5 1791.8751 2.61 57330 25604 2 1791.875478 896.9448 Matrin-3 OS=Homo sapiens OX=9606 GN=MATR3 PE=1 SV=2 4.21 3974.6 - 4.22E+06 - - - 0.1881 - 4.05 0.707 - 1589.5 1 2 0 0.0003 18 0 0 0 4.78E+07 1.83E+07 - - - 7.7016 1 221125_WJC_METTL3_EV_vs_WT_F04.25613.25613.3 3.76E-09 13/96 R.GGSDPETTGIQIWSEVFTVEKPGGK.K "sp|Q6DD88|ATLA3_HUMAN,tr|F5H6I7|F5H6I7_HUMAN" 2 2618.2864 0.11 57337 25613 3 2618.29218 873.7694 Atlastin-3 OS=Homo sapiens OX=9606 GN=ATL3 PE=1 SV=1 4.41 3975.9 - 382476 - - - 2.203 - 2.996 0.583 - 153.2 1 2 0 0.0058 25 0 0 0 2.01E+06 1.75E+07 - - - 7.5627 1 221125_WJC_METTL3_EV_vs_WT_F04.25616.25616.3 2.59E-09 22/68 R.GGHPPAIQSLINLLADNR.Y sp|Q9HCD5|NCOA5_HUMAN 1 1885.017 2.23 57339 25616 3 1885.017275 629.3463 Nuclear receptor coactivator 5 OS=Homo sapiens OX=9606 GN=NCOA5 PE=1 SV=2 6.74 3976.3 - 1.50E+06 - - - 0.1485 - 4.233 0.596 - 692.5 1 2 0 0.0003 18 0 0 0 6.18E+07 2.77E+07 - - - 8.7777 1 221125_WJC_METTL3_EV_vs_WT_F04.25619.25619.3 2.20E-07 15/64 K.K[136.11]EDLVFIFWAPESAPLK[136.11].S "sp|P23528|COF1_HUMAN,sp|Q9Y281|COF2_HUMAN,tr|E9PP50|E9PP50_HUMAN,tr|G3V1A4|G3V1A4_HUMAN,tr|E9PQB7|E9PQB7_HUMAN,tr|E9PK25|E9PK25_HUMAN" 6 2005.0896 1.23 57341 25619 3 2005.092815 669.3705 Cofilin-1 OS=Homo sapiens OX=9606 GN=CFL1 PE=1 SV=3 4.68 3976.6 - 302246 - - - 1.6279 - 3.155 0.544 - 245.2 1 2 0 0.0033 17 0 0 0 2.69E+06 2.18E+06 - - - 7.5068 1 221125_WJC_METTL3_EV_vs_WT_F04.25620.25620.4 1.66E-18 45/180 K.TIFTGHTAVVEDVSWHLLHESLFGSVADDQK.L sp|Q09028|RBBP4_HUMAN 1 3437.6892 1.38 57342 25620 4 3437.689813 860.4296 Histone-binding protein RBBP4 OS=Homo sapiens OX=9606 GN=RBBP4 PE=1 SV=3 4.77 3976.8 - 2.18E+06 - - - 0.1827 - 6.616 0.707 - 1325.8 1 2 0 0.0006 31 0 0 0 1.92E+07 1.39E+07 - - - 5.9538 0.9998 221125_WJC_METTL3_EV_vs_WT_F04.25622.25622.4 1.05E-05 18/156 K.ALTVGGFIEEEKEDLLQHFSTANQGPK.F sp|Q9P2N5|RBM27_HUMAN 1 2957.4771 0.72 57344 25622 4 2957.472471 740.3765 RNA-binding protein 27 OS=Homo sapiens OX=9606 GN=RBM27 PE=1 SV=2 4.57 3977 - 330876 - - - -1.554 - 3.295 0.462 - 165.8 1 2 1 -0.0046 27 0 0 0 3.40E+06 4.71E+06 - - - 3.6191 0.9997 221125_WJC_METTL3_EV_vs_WT_F04.25627.25627.4 0.000214 29/162 R.QKLEAQLTENNIVKEELALLDGSNVVFK.L "sp|O15212|PFD6_HUMAN,tr|A2AB88|A2AB88_HUMAN" 2 3141.6921 27.02 57347 25627 4 3141.699166 786.4303 Prefoldin subunit 6 OS=Homo sapiens OX=9606 GN=PFDN6 PE=1 SV=1 4.59 3977.7 - 2.29E+06 - - - 2.2348 - 3.982 0.465 - 332 1 2 2 0.007 28 0 0 0 9.89E+07 3.66E+06 - - - 3.7004 1 221125_WJC_METTL3_EV_vs_WT_F04.25635.25635.4 1.91E-11 22/186 R.ENLASDMYLISQMDSDQYVPITTVANLDHIKK.L sp|Q92615|LAR4B_HUMAN 1 3651.78 1.19 57353 25635 4 3651.778326 913.9523 La-related protein 4B OS=Homo sapiens OX=9606 GN=LARP4B PE=1 SV=3 4.35 3978.7 - 1.05E+06 - - - -0.4721 - 4.095 0.66 - 142.4 1 2 0 -0.0017 32 0 0 0 5.03E+06 4.21E+06 - - - 5.3958 0.9999 221125_WJC_METTL3_EV_vs_WT_F04.25638.25638.4 1.92E-08 24/180 K.AKGPVTIPYPLFQSHVEDLYVEGLPEGIPFR.R "sp|P78347|GTF2I_HUMAN,tr|A0A494C1K3|A0A494C1K3_HUMAN" 2 3467.8129 1.81 57356 25638 4 3467.81994 867.9605 General transcription factor II-I OS=Homo sapiens OX=9606 GN=GTF2I PE=1 SV=2 4.83 3979 - 1.28E+06 - - - 2.0217 - 3.089 0.576 - 158 1 2 1 0.007 31 0 0 0 5.68E+06 3.15E+06 - - - 4.5803 1 221125_WJC_METTL3_EV_vs_WT_F04.25641.25641.3 1.41E-07 Nov-84 K.TSTSNVEQYQAMVTSLEESLNK.E sp|P12270|TPR_HUMAN 1 2458.1533 2.91 57359 25641 3 2458.152769 820.3917 Nucleoprotein TPR OS=Homo sapiens OX=9606 GN=TPR PE=1 SV=3 4.25 3979.4 - 479738 - - - -0.2359 - 2.851 0.584 - 112.5 1 2 0 -0.0006 22 0 0 0 1.80E+06 6.18E+05 - - - 7.5347 0.9989 221125_WJC_METTL3_EV_vs_WT_F04.25643.25643.3 3.02E-07 13/72 G.VTIAQGGVLPNIQAVLLPK.K "sp|P16104|H2AX_HUMAN,sp|Q9BTM1|H2AJ_HUMAN,sp|Q93077|H2A1C_HUMAN,sp|Q99878|H2A1J_HUMAN,sp|Q16777|H2A2C_HUMAN,sp|Q8IUE6|H2A2B_HUMAN,sp|Q96QV6|H2A1A_HUMAN,sp|P04908|H2A1B_HUMAN,sp|P20671|H2A1D_HUMAN,sp|P0C0S8|H2A1_HUMAN,sp|Q6FI13|H2A2A_HUMAN,sp|Q96KK5|H2A1H_HUMAN,sp|Q7L7L0|H2A3_HUMAN,tr|A0A0U1RR32|A0A0U1RR32_HUMAN,tr|A0A0U1RRH7|A0A0U1RRH7_HUMAN,tr|H0YFX9|H0YFX9_HUMAN" 16 1930.1615 1.61 57361 25643 3 1930.161529 644.3945 Histone H2AX OS=Homo sapiens OX=9606 GN=H2AX PE=1 SV=2 8.72 3979.7 - 256639 - - - -0.0026 - 3.023 0.616 - 169.8 1 1 0 0 19 0 0 0 5.83E+06 3.62E+06 - - - 8.1256 1 221125_WJC_METTL3_EV_vs_WT_F04.25648.25648.3 1.53E-17 28/116 K.DMAIATGGAVFGEEGLTLNLEDVQPHDLGK.V "sp|P10809|CH60_HUMAN,tr|A0A7I2V2X6|A0A7I2V2X6_HUMAN,tr|A0A7I2YQK6|A0A7I2YQK6_HUMAN,tr|A0A7I2V599|A0A7I2V599_HUMAN" 4 3096.5074 1.36 57364 25648 3 3096.506172 1033.1764 "60 kDa heat shock protein, mitochondrial OS=Homo sapiens OX=9606 GN=HSPD1 PE=1 SV=2" 4.01 3980.3 - 1.70E+06 - - - -0.3904 - 4.747 0.745 - 497.5 1 2 0 -0.0012 30 0 0 0 4.42E+07 3.26E+07 - - - 10.429 1 221125_WJC_METTL3_EV_vs_WT_F04.25651.25651.3 4.00E-07 16/68 K.K[136.11]DDNGIGTAIDFVLSNAR[166.11].L "sp|Q9NQG6|MID51_HUMAN,tr|B0QY95|B0QY95_HUMAN,tr|B0QY94|B0QY94_HUMAN" 3 1922.9817 0.77 57367 25651 3 1922.97698 642.0012 Mitochondrial dynamics protein MID51 OS=Homo sapiens OX=9606 GN=MIEF1 PE=1 SV=1 4.43 3980.7 - 742793 - - - -2.4415 - 3.217 0.585 - 279.2 1 2 0 -0.0047 18 0 0 0 3.04E+06 3.94E+06 - - - 7.9704 1 221125_WJC_METTL3_EV_vs_WT_F04.25655.25655.4 7.21E-13 27/246 R.ELSQGLLPLPQPYQAQGVLASQALSQGSEPSSENANDTIILR.N sp|P98175|RBM10_HUMAN 1 4419.2558 3.66 57369 25655 4 4419.260662 1105.8212 RNA-binding protein 10 OS=Homo sapiens OX=9606 GN=RBM10 PE=1 SV=3 4 3981.2 - 1.81E+06 - - - 1.1029 - 4.827 0.656 - 223.9 1 2 0 0.0049 42 0 0 0 1.02E+07 2.78E+06 - - - 5.3846 1 221125_WJC_METTL3_EV_vs_WT_F04.25656.25656.3 2.93E-08 17/68 K.KDDNGIGTAIDFVLSNAR.L "sp|Q9NQG6|MID51_HUMAN,tr|B0QY95|B0QY95_HUMAN,tr|B0QY94|B0QY94_HUMAN" 3 1904.9592 0.8 57370 25656 3 1904.958797 635.9937 Mitochondrial dynamics protein MID51 OS=Homo sapiens OX=9606 GN=MIEF1 PE=1 SV=1 4.43 3981.3 - 406560 - - - -0.2142 - 3.081 0.616 - 338.1 1 2 0 -0.0004 18 0 0 0 3.04E+06 3.79E+06 - - - 8.2097 1 221125_WJC_METTL3_EV_vs_WT_F04.25664.25664.4 3.05E-14 37/234 W.SATHSYLDPPLVTPFPNTGFINGFTSPAFKPAASPLTSLR.Q sp|Q92615|LAR4B_HUMAN 1 4216.1633 1.54 57376 25664 4 4216.166311 1055.0481 La-related protein 4B OS=Homo sapiens OX=9606 GN=LARP4B PE=1 SV=3 8.33 3982.4 - 1.25E+06 - - - 0.7066 - 4.817 0.729 - 497.2 1 1 0 0.003 40 0 0 0 7.38E+06 4.79E+06 - - - 6.0242 0.9999 221125_WJC_METTL3_EV_vs_WT_F04.25666.25666.4 0.00119 22/114 R.KRLEEALMADMLAHVEELAR.D "sp|O95983|MBD3_HUMAN,tr|K7EIE8|K7EIE8_HUMAN" 2 2324.1981 1.03 57378 25666 4 2324.199151 582.0568 Methyl-CpG-binding domain protein 3 OS=Homo sapiens OX=9606 GN=MBD3 PE=1 SV=1 4.96 3982.6 - 206586 - - - 0.4642 - 4.03 0.562 - 593.8 1 2 1 0.0011 20 0 0 0 1.91E+06 1.86E+06 - - - 4.5833 1 221125_WJC_METTL3_EV_vs_WT_F04.25669.25669.3 1.29E-09 18/76 R.INNEIDQLMNQMQQIETQQR.K sp|Q9UQE7|SMC3_HUMAN 1 2473.169 0.87 57379 25669 3 2473.170445 825.3969 Structural maintenance of chromosomes protein 3 OS=Homo sapiens OX=9606 GN=SMC3 PE=1 SV=2 4.14 3983 - 664362 - - - 0.6017 - 3.512 0.624 - 455.5 1 2 0 0.0015 20 0 0 0 7.22E+06 8.32E+06 - - - 8.5441 1 221125_WJC_METTL3_EV_vs_WT_F04.25671.25671.3 4.56E-10 17/116 K.DMAIATGGAVFGEEGLTLNLEDVQPHDLGK[136.11].V "sp|P10809|CH60_HUMAN,tr|A0A7I2V2X6|A0A7I2V2X6_HUMAN,tr|A0A7I2YQK6|A0A7I2YQK6_HUMAN,tr|A0A7I2V599|A0A7I2V599_HUMAN" 4 3104.5216 1.36 57381 25671 3 3104.521339 1035.8478 "60 kDa heat shock protein, mitochondrial OS=Homo sapiens OX=9606 GN=HSPD1 PE=1 SV=2" 4.01 3983.3 - 1.67E+06 - - - -0.078 - 3.953 0.571 - 154 1 2 0 -0.0002 30 0 0 0 4.53E+07 3.33E+07 - - - 8.0682 0.9718 221125_WJC_METTL3_EV_vs_WT_F04.25675.25675.3 5.66E-06 Nov-76 K.GNPQGFNQGLDC[160.03]DVIVAEVR[166.11].S sp|Q86U44|MTA70_HUMAN 1 2197.0461 0.01 57385 25675 3 2198.038804 733.356 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 4.03 3983.8 - 159671 - - - 451.8194 - 2.132 0.49 - 134.9 1 2 0 0.9927 20 0 0 0 2.13E+05 1.71E+07 - - - 5.5647 1 221125_WJC_METTL3_EV_vs_WT_F04.25679.25679.4 2.34E-10 22/120 R.K[136.11]FDVNTSAVQVLIEHIGNLDR[166.11].A "sp|Q00610|CLH1_HUMAN,tr|A0A087WVQ6|A0A087WVQ6_HUMAN" 2 2385.2771 0.94 57387 25679 4 2385.27428 597.3266 Clathrin heavy chain 1 OS=Homo sapiens OX=9606 GN=CLTC PE=1 SV=5 5.38 3984.3 - 1.76E+06 - - - -1.1944 - 4.235 0.454 - 455.6 1 2 0 -0.0028 21 0 0 0 1.48E+07 1.57E+07 - - - 3.6541 1 221125_WJC_METTL3_EV_vs_WT_F04.25681.25681.4 7.11E-10 26/120 R.KFDVNTSAVQVLIEHIGNLDR.A "sp|Q00610|CLH1_HUMAN,tr|A0A087WVQ6|A0A087WVQ6_HUMAN" 2 2367.2547 0.94 57389 25681 4 2367.254419 592.8209 Clathrin heavy chain 1 OS=Homo sapiens OX=9606 GN=CLTC PE=1 SV=5 5.38 3984.5 - 1.62E+06 - - - -0.1014 - 4.226 0.527 - 630.5 1 2 0 -0.0002 21 0 0 0 1.48E+07 1.57E+07 - - - 4.2895 1 221125_WJC_METTL3_EV_vs_WT_F04.25683.25683.3 2.29E-15 22/112 K.ENGTVTAANASTLNDGAAALVLMTADAAK.R "sp|P24752|THIL_HUMAN,tr|A0A5F9ZHJ7|A0A5F9ZHJ7_HUMAN,tr|A0A5F9ZHD4|A0A5F9ZHD4_HUMAN,tr|A0A5F9ZHJ0|A0A5F9ZHJ0_HUMAN,tr|A0A5F9ZHL1|A0A5F9ZHL1_HUMAN,tr|A0A5F9ZI66|A0A5F9ZI66_HUMAN" 6 2760.36 2.95 57391 25683 3 2760.365534 921.1273 "Acetyl-CoA acetyltransferase, mitochondrial OS=Homo sapiens OX=9606 GN=ACAT1 PE=1 SV=1" 4.03 3984.7 - 592094 - - - 2.0092 - 3.92 0.724 - 417.2 1 2 0 0.0055 29 0 0 0 3.12E+06 1.06E+06 - - - 9.7532 0.9981 221125_WJC_METTL3_EV_vs_WT_F04.25690.25690.3 0.00773 May-84 R.VFTTQELVQAFTHAPATLEADR[166.11].G "sp|O95433|AHSA1_HUMAN,tr|H0YJ63|H0YJ63_HUMAN,tr|G3V438|G3V438_HUMAN,tr|H0YJG7|H0YJG7_HUMAN" 4 2454.2419 0.66 57395 25690 3 2454.238453 819.0879 Activator of 90 kDa heat shock protein ATPase homolog 1 OS=Homo sapiens OX=9606 GN=AHSA1 PE=1 SV=1 4.65 3985.7 - 268477 - - - -1.3878 - 1.482 0.335 - 20.6 3 2 0 -0.0034 22 0 0 0 1.05E+06 1.58E+06 - - - 2.9858 1 221125_WJC_METTL3_EV_vs_WT_F04.25703.25703.3 8.13E-09 16/84 K.ETIEDVEEMLNNLPGVTSVHSR.F "sp|Q9UNM6|PSD13_HUMAN,tr|J3KNQ3|J3KNQ3_HUMAN,tr|E9PL38|E9PL38_HUMAN,tr|H0YD73|H0YD73_HUMAN,tr|A0A087WUL9|A0A087WUL9_HUMAN" 5 2468.1853 0.64 57402 25703 3 2468.17853 823.7357 26S proteasome non-ATPase regulatory subunit 13 OS=Homo sapiens OX=9606 GN=PSMD13 PE=1 SV=2 4.25 3987.3 - 384091 - - - -2.7502 - 3.256 0.599 - 114.6 1 2 0 -0.0068 22 0 0 0 3.74E+06 5.85E+06 - - - 8.0151 1 221125_WJC_METTL3_EV_vs_WT_F04.25704.25704.3 5.31E-08 26/104 K.EGTDSSQGIPQLVSNISAC[160.03]QVIAEAVR[166.11].T "sp|Q99832|TCPH_HUMAN,tr|A0A0D9SG95|A0A0D9SG95_HUMAN,tr|F8WBP8|F8WBP8_HUMAN" 3 2838.4057 0.14 57403 25704 3 2838.415204 947.1425 T-complex protein 1 subunit eta OS=Homo sapiens OX=9606 GN=CCT7 PE=1 SV=2 4.14 3987.4 - 1.64E+06 - - - 3.3459 - 4.188 0.647 - 515.7 1 2 0 0.0095 27 0 0 0 6.00E+06 4.43E+07 - - - 9.0458 0.9999 221125_WJC_METTL3_EV_vs_WT_F04.25705.25705.4 5.99E-10 27/234 R.LAGLEQAILSPGQNSGNYFAPIPLEDHAENKVDILEMLQK.A "sp|Q9NRA8|4ET_HUMAN,tr|B1AKL4|B1AKL4_HUMAN" 2 4362.2206 1.85 57404 25705 4 4362.226526 1091.5624 Eukaryotic translation initiation factor 4E transporter OS=Homo sapiens OX=9606 GN=EIF4ENIF1 PE=1 SV=2 4.35 3987.6 - 1.07E+06 - - - 1.361 - 4.22 0.547 - 252.3 1 2 1 0.0059 40 0 0 0 4.28E+06 2.31E+06 - - - 4.4011 1 221125_WJC_METTL3_EV_vs_WT_F04.25710.25710.3 1.19E-09 21/84 K.ETIEDVEEMLNNLPGVTSVHSR[166.11].F "sp|Q9UNM6|PSD13_HUMAN,tr|J3KNQ3|J3KNQ3_HUMAN,tr|E9PL38|E9PL38_HUMAN,tr|H0YD73|H0YD73_HUMAN,tr|A0A087WUL9|A0A087WUL9_HUMAN" 5 2478.1936 0.64 57407 25710 3 2478.195811 827.0718 26S proteasome non-ATPase regulatory subunit 13 OS=Homo sapiens OX=9606 GN=PSMD13 PE=1 SV=2 4.25 3988.2 - 1.53E+06 - - - 0.897 - 3.723 0.591 - 259.9 1 2 0 0.0022 22 0 0 0 3.74E+06 5.85E+06 - - - 8.245 0.9998 221125_WJC_METTL3_EV_vs_WT_F04.25713.25713.4 2.23E-07 17/162 K.QLHEQAMQFGQLLTHLDTTQQMIANSLK.D "sp|Q13561|DCTN2_HUMAN,tr|H0YI98|H0YI98_HUMAN,tr|A8K8J9|A8K8J9_HUMAN,tr|A0A7I2V4H4|A0A7I2V4H4_HUMAN,tr|A0A7I2V4Y9|A0A7I2V4Y9_HUMAN" 5 3223.6118 3.14 57410 25713 4 3223.627382 806.9102 Dynactin subunit 2 OS=Homo sapiens OX=9606 GN=DCTN2 PE=1 SV=4 5.99 3988.6 - 329913 - - - 4.8328 - 3.422 0.601 - 187.7 1 2 0 0.0156 28 0 0 0 2.08E+06 6.63E+05 - - - 4.8347 0.9986 221125_WJC_METTL3_EV_vs_WT_F04.25715.25715.4 1.92E-05 10/186 R.QGPPHINHDDPSLVPNVPYFDLPAGLMAPLVK.L "sp|Q8IWX8|CHERP_HUMAN,tr|J3QK89|J3QK89_HUMAN" 2 3447.7649 0.58 57412 25715 4 3447.786843 862.9485 Calcium homeostasis endoplasmic reticulum protein OS=Homo sapiens OX=9606 GN=CHERP PE=1 SV=3 5.13 3988.9 - 302190 - - - 6.3548 - 2.038 0.498 - 37.3 1 2 0 0.0219 32 0 0 0 1.01E+06 1.75E+06 - - - 3.7695 0.9981 221125_WJC_METTL3_EV_vs_WT_F04.25719.25719.2 6.27E-05 20-Oct R.NPEAALSPTFR[166.11].S "sp|Q86U44|MTA70_HUMAN,tr|B4E349|B4E349_HUMAN,tr|F5H6D8|F5H6D8_HUMAN,tr|B4DTN4|B4DTN4_HUMAN" 4 1211.6174 0.01 57416 25719 2 1211.623366 606.816 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 6 3989.4 - 147377 - - - 4.9182 - 2.25 0.529 - 315.5 1 2 0 0.006 11 0 0 0 2.85E+04 3.21E+06 - - - 5.1401 0.9982 221125_WJC_METTL3_EV_vs_WT_F04.25720.25720.2 0.00192 18-Jul K.FAAQELIEVK[136.11].R "sp|Q86U44|MTA70_HUMAN,tr|F5H6D8|F5H6D8_HUMAN,tr|H0YFV6|H0YFV6_HUMAN,tr|B4DTN4|B4DTN4_HUMAN" 4 1154.6427 0.02 57417 25720 2 1154.645885 578.3286 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 4.53 3989.5 - 119494 - - - 2.7801 - 1.414 0.418 - 107.7 1 2 0 0.0032 10 0 0 0 6.23E+04 3.75E+06 - - - 3.0943 0.9996 221125_WJC_METTL3_EV_vs_WT_F04.25722.25722.3 0.000105 Nov-56 R.RGVMLAVDAVIAELK.K "sp|P10809|CH60_HUMAN,tr|A0A7I2V2X6|A0A7I2V2X6_HUMAN,tr|A0A7I2V599|A0A7I2V599_HUMAN,tr|E7EXB4|E7EXB4_HUMAN,tr|A0A7I2YQ71|A0A7I2YQ71_HUMAN,tr|E7ESH4|E7ESH4_HUMAN,tr|A0A7I2V5M1|A0A7I2V5M1_HUMAN,tr|A0A7I2V5K3|A0A7I2V5K3_HUMAN,tr|A0A7I2V369|A0A7I2V369_HUMAN" 9 1583.9069 -1 57419 25722 3 1583.91364 528.9762 "60 kDa heat shock protein, mitochondrial OS=Homo sapiens OX=9606 GN=HSPD1 PE=1 SV=2" 6.07 3989.8 - 65020.9 - - - 4.2559 - 2.154 0.496 - 172.1 1 2 0 0.0067 15 0 0 0 0.00E+00 0.00E+00 - - - 6.0703 1 221125_WJC_METTL3_EV_vs_WT_F04.25725.25725.4 4.12E-12 37/150 K.SISHYHETLGEALQGVELEFSGLDIK.F "sp|Q9HD45|TM9S3_HUMAN,tr|Q5TB53|Q5TB53_HUMAN" 2 2871.4291 1.51 57420 25725 4 2871.438712 718.8645 Transmembrane 9 superfamily member 3 OS=Homo sapiens OX=9606 GN=TM9SF3 PE=1 SV=2 4.56 3990.2 - 1.96E+06 - - - 3.3635 - 5.728 0.699 - 927.7 1 2 0 0.0097 26 0 0 0 2.12E+07 1.40E+07 - - - 5.858 1 221125_WJC_METTL3_EV_vs_WT_F04.25726.25726.3 1.11E-10 25/104 K.EGTDSSQGIPQLVSNISAC[160.03]QVIAEAVR.T "sp|Q99832|TCPH_HUMAN,tr|A0A0D9SG95|A0A0D9SG95_HUMAN,tr|F8WBP8|F8WBP8_HUMAN" 3 2828.3974 0.14 57421 25726 3 2828.405269 943.8064 T-complex protein 1 subunit eta OS=Homo sapiens OX=9606 GN=CCT7 PE=1 SV=2 4.14 3990.3 - 1.08E+06 - - - 2.7691 - 4.293 0.691 - 505.7 1 2 0 0.0078 27 0 0 0 6.00E+06 4.39E+07 - - - 9.5938 1 221125_WJC_METTL3_EV_vs_WT_F04.25727.25727.4 4.58E-13 35/150 K.SISHYHETLGEALQGVELEFSGLDIK[136.11].F "sp|Q9HD45|TM9S3_HUMAN,tr|Q5TB53|Q5TB53_HUMAN" 2 2879.4433 1.51 57422 25727 4 2879.449929 720.8681 Transmembrane 9 superfamily member 3 OS=Homo sapiens OX=9606 GN=TM9SF3 PE=1 SV=2 4.56 3990.4 - 1.24E+06 - - - 2.3182 - 5.479 0.629 - 853.2 1 2 0 0.0067 26 0 0 0 2.12E+07 1.40E+07 - - - 5.2355 1 221125_WJC_METTL3_EV_vs_WT_F04.25728.25728.3 4.14E-12 25/72 K.NVVHQLSVTLEDLYNGATR[166.11].K sp|P31689|DNJA1_HUMAN 1 2138.0996 0.48 57423 25728 3 2138.107266 713.7071 DnaJ homolog subfamily A member 1 OS=Homo sapiens OX=9606 GN=DNAJA1 PE=1 SV=2 5.32 3990.6 - 802275 - - - 3.6079 - 3.79 0.622 - 800.9 1 2 0 0.0077 19 0 0 0 2.47E+07 5.17E+07 - - - 8.7459 1 221125_WJC_METTL3_EV_vs_WT_F04.25738.25738.3 1.06E-08 Dec-60 R.THNLEPYFESFINNLR.R sp|P04264|K2C1_HUMAN 1 1992.9694 999 57433 25738 3 1992.975327 665.3304 "Keratin, type II cytoskeletal 1 OS=Homo sapiens OX=9606 GN=KRT1 PE=1 SV=6" 5.37 3991.9 - 110532 - - - 2.986 - 2.408 0.642 - 241.8 1 2 0 0.006 16 0 0 0 2.59E+07 0.00E+00 - - - 7.9509 1 221125_WJC_METTL3_EV_vs_WT_F04.25740.25740.3 3.97E-13 21/84 R.K[136.11]PLVIIAEDVDGEALSTLVLNR[166.11].L "sp|P10809|CH60_HUMAN,tr|A0A7I2V2X6|A0A7I2V2X6_HUMAN,tr|A0A7I2YQK6|A0A7I2YQK6_HUMAN,tr|A0A7I2V599|A0A7I2V599_HUMAN,tr|A0A7I2YQ71|A0A7I2YQ71_HUMAN,tr|A0A7I2V5M1|A0A7I2V5M1_HUMAN,tr|A0A7I2V5K3|A0A7I2V5K3_HUMAN" 7 2382.3489 1.12 57434 25740 3 2382.353973 795.1236 "60 kDa heat shock protein, mitochondrial OS=Homo sapiens OX=9606 GN=HSPD1 PE=1 SV=2" 4.32 3992.1 - 506785 - - - 2.1307 - 4.064 0.692 - 495.9 1 2 0 0.0051 22 0 0 0 9.01E+06 8.02E+06 - - - 9.578 1 221125_WJC_METTL3_EV_vs_WT_F04.25742.25742.3 1.08E-17 31/100 K.SISHYHETLGEALQGVELEFSGLDIK.F "sp|Q9HD45|TM9S3_HUMAN,tr|Q5TB53|Q5TB53_HUMAN" 2 2871.4291 1.3 57435 25742 3 2871.436822 958.1503 Transmembrane 9 superfamily member 3 OS=Homo sapiens OX=9606 GN=TM9SF3 PE=1 SV=2 4.56 3992.3 - 1.15E+06 - - - 2.7053 - 5.803 0.717 - 1131.5 1 2 0 0.0078 26 0 0 0 4.44E+06 3.41E+06 - - - 10.5771 1 221125_WJC_METTL3_EV_vs_WT_F04.25743.25743.3 3.31E-09 30/100 K.SISHYHETLGEALQGVELEFSGLDIK[136.11].F "sp|Q9HD45|TM9S3_HUMAN,tr|Q5TB53|Q5TB53_HUMAN" 2 2879.4433 1.3 57436 25743 3 2879.450731 960.8217 Transmembrane 9 superfamily member 3 OS=Homo sapiens OX=9606 GN=TM9SF3 PE=1 SV=2 4.56 3992.5 - 711162 - - - 2.5967 - 5.224 0.669 - 1123.9 1 2 0 0.0075 26 0 0 0 4.44E+06 3.41E+06 - - - 9.8002 0.9999 221125_WJC_METTL3_EV_vs_WT_F04.25744.25744.4 8.56E-09 21/144 K.KRIEPLSPELVAAASAVADSLPFDK.Q sp|Q92665|RT31_HUMAN 1 2623.4221 1.06 57437 25744 4 2623.428457 656.8628 "28S ribosomal protein S31, mitochondrial OS=Homo sapiens OX=9606 GN=MRPS31 PE=1 SV=3" 4.78 3992.6 - 654509 - - - 2.4163 - 3.389 0.604 - 192.5 1 2 1 0.0063 25 0 0 0 3.75E+06 3.54E+06 - - - 4.8697 0.9998 221125_WJC_METTL3_EV_vs_WT_F04.25745.25745.4 0.000978 13/108 K.NVVHQLSVTLEDLYNGATR[166.11].K sp|P31689|DNJA1_HUMAN 1 2138.0996 0.59 57438 25745 4 2138.102306 535.5322 DnaJ homolog subfamily A member 1 OS=Homo sapiens OX=9606 GN=DNAJA1 PE=1 SV=2 5.32 3992.7 - 637497 - - - 1.2881 - 2.226 0.389 - 84.2 1 2 0 0.0028 19 0 0 0 1.93E+06 3.28E+06 - - - 2.8818 1 221125_WJC_METTL3_EV_vs_WT_F04.25761.25761.4 1.14E-11 16/144 K.K[136.11]R[166.11]IEPLSPELVAAASAVADSLPFDK[136.11].Q sp|Q92665|RT31_HUMAN 1 2649.4588 1.59 57452 25761 4 2649.459784 663.372 "28S ribosomal protein S31, mitochondrial OS=Homo sapiens OX=9606 GN=MRPS31 PE=1 SV=3" 4.78 3994.8 - 428175 - - - 0.3759 - 3.352 0.649 - 128.2 1 2 1 0.001 25 0 0 0 3.75E+06 2.36E+06 - - - 5.2594 0.9997 221125_WJC_METTL3_EV_vs_WT_F04.25762.25762.2 4.43E-07 13/30 K.AAGVNVEPFWPGLFAK.A sp|P05386|RLA1_HUMAN 1 1701.8879 1.97 57453 25762 2 1701.891978 851.9512 60S acidic ribosomal protein P1 OS=Homo sapiens OX=9606 GN=RPLP1 PE=1 SV=1 6.05 3994.9 - 277003 - - - 2.4091 - 2.801 0.517 - 392.7 1 2 0 0.0041 16 0 0 0 2.86E+06 1.45E+06 - - - 5.3905 1 221125_WJC_METTL3_EV_vs_WT_F04.25765.25765.3 8.45E-14 27/84 R.KPLVIIAEDVDGEALSTLVLNR.L "sp|P10809|CH60_HUMAN,tr|A0A7I2V2X6|A0A7I2V2X6_HUMAN,tr|A0A7I2YQK6|A0A7I2YQK6_HUMAN,tr|A0A7I2V599|A0A7I2V599_HUMAN,tr|A0A7I2YQ71|A0A7I2YQ71_HUMAN,tr|A0A7I2V5M1|A0A7I2V5M1_HUMAN,tr|A0A7I2V5K3|A0A7I2V5K3_HUMAN" 7 2364.3264 1.15 57455 25765 3 2364.330392 789.1161 "60 kDa heat shock protein, mitochondrial OS=Homo sapiens OX=9606 GN=HSPD1 PE=1 SV=2" 4.32 3995.4 - 625160 - - - 1.677 - 4.623 0.692 - 929.8 1 2 0 0.004 22 0 0 0 9.01E+06 7.82E+06 - - - 9.8839 1 221125_WJC_METTL3_EV_vs_WT_F04.25767.25767.3 1.56E-09 18/120 K.SSSLQVADQDLLPSFHPYQPLEC[160.03]IVEETEGK.L "sp|Q8IWZ3|ANKH1_HUMAN,tr|E9PDP5|E9PDP5_HUMAN" 2 3515.6766 1.76 57456 25767 3 3515.679437 1172.8995 Ankyrin repeat and KH domain-containing protein 1 OS=Homo sapiens OX=9606 GN=ANKHD1 PE=1 SV=1 4.08 3995.6 - 683009 - - - 0.7981 - 3.415 0.563 - 209.6 1 2 0 0.0028 31 0 0 0 4.02E+06 2.28E+06 - - - 7.6417 1 221125_WJC_METTL3_EV_vs_WT_F04.25768.25768.4 4.79E-10 17/180 K.SSSLQVADQDLLPSFHPYQPLEC[160.03]IVEETEGK.L "sp|Q8IWZ3|ANKH1_HUMAN,tr|E9PDP5|E9PDP5_HUMAN" 2 3515.6766 1.12 57457 25768 4 3515.677379 879.9264 Ankyrin repeat and KH domain-containing protein 1 OS=Homo sapiens OX=9606 GN=ANKHD1 PE=1 SV=1 4.08 3995.7 - 452144 - - - 0.2128 - 3.429 0.563 - 149.9 1 2 0 0.0007 31 0 0 0 2.11E+06 1.89E+06 - - - 4.5007 1 221125_WJC_METTL3_EV_vs_WT_F04.25773.25773.3 1.85E-05 15/120 K.SSSLQVADQDLLPSFHPYQPLEC[160.03]IVEETEGK[136.11].L "sp|Q8IWZ3|ANKH1_HUMAN,tr|E9PDP5|E9PDP5_HUMAN" 2 3523.6908 1.76 57461 25773 3 3523.698418 1175.5709 Ankyrin repeat and KH domain-containing protein 1 OS=Homo sapiens OX=9606 GN=ANKHD1 PE=1 SV=1 4.08 3996.4 - 395622 - - - 2.1531 - 2.922 0.537 - 139.5 1 2 0 0.0076 31 0 0 0 4.02E+06 2.28E+06 - - - 6.9918 1 221125_WJC_METTL3_EV_vs_WT_F04.25774.25774.4 5.05E-11 15/168 R.DYLGDFIEHYAQLGPSQPPDLAQAQDEPR.R sp|Q00577|PURA_HUMAN 1 3269.5265 7.3 57462 25774 4 3269.527886 818.3889 Transcriptional activator protein Pur-alpha OS=Homo sapiens OX=9606 GN=PURA PE=1 SV=2 3.96 3996.5 - 251177 - - - 0.4129 - 3.346 0.639 - 108.4 1 2 0 0.0013 29 0 0 0 9.78E+05 1.34E+05 - - - 5.1597 0.9707 221125_WJC_METTL3_EV_vs_WT_F04.25783.25783.3 7.44E-06 Nov-68 H.ASASSTNLKDILADLIPK.E "sp|O75390|CISY_HUMAN,tr|B4DJV2|B4DJV2_HUMAN,tr|F8W031|F8W031_HUMAN,tr|F8VR34|F8VR34_HUMAN,tr|F8W4S1|F8W4S1_HUMAN,tr|F8VP03|F8VP03_HUMAN,tr|F8VU34|F8VU34_HUMAN,tr|F8W0J2|F8W0J2_HUMAN,tr|F8VTT8|F8VTT8_HUMAN,tr|F8VWQ5|F8VWQ5_HUMAN" 10 1856.0255 1.29 57469 25783 3 1856.028777 619.6824 "Citrate synthase, mitochondrial OS=Homo sapiens OX=9606 GN=CS PE=1 SV=2" 6 3997.7 - 367488 - - - 1.7688 - 2.182 0.517 - 81.5 1 1 1 0.0033 18 0 0 0 3.44E+06 2.66E+06 - - - 6.246 1 221125_WJC_METTL3_EV_vs_WT_F04.25785.25785.3 3.84E-07 Dec-64 K.TTQVPQFILDDFIQNDR[166.11].A sp|Q08211|DHX9_HUMAN 1 2059.025 0.68 57471 25785 3 2059.024899 687.3489 ATP-dependent RNA helicase A OS=Homo sapiens OX=9606 GN=DHX9 PE=1 SV=4 3.93 3998 - 208767 - - - -0.0442 - 2.541 0.522 - 278.1 1 2 0 -0.0001 17 0 0 0 6.59E+05 9.69E+05 - - - 6.7157 0.9997 221125_WJC_METTL3_EV_vs_WT_F04.25789.25789.3 0.000659 Nov-64 K.ATENDIYNFFSPLNPVR[166.11].V "sp|P52597|HNRPF_HUMAN,sp|P31943|HNRH1_HUMAN,tr|H0YBD7|H0YBD7_HUMAN,tr|H0YB39|H0YB39_HUMAN,tr|H0YBG7|H0YBG7_HUMAN,tr|E9PCY7|E9PCY7_HUMAN,tr|G8JLB6|G8JLB6_HUMAN" 7 2005.9773 1.58 57473 25789 3 2005.983977 669.6664 Heterogeneous nuclear ribonucleoprotein F OS=Homo sapiens OX=9606 GN=HNRNPF PE=1 SV=3 4.37 3998.5 - 335493 - - - 3.3231 - 2.257 0.457 - 119.8 1 2 0 0.0067 17 0 0 0 2.72E+06 1.73E+06 - - - 5.6898 0.9999 221125_WJC_METTL3_EV_vs_WT_F04.25790.25790.3 1.19E-08 13/64 K.ATENDIYNFFSPLNPVR.V "sp|P52597|HNRPF_HUMAN,sp|P31943|HNRH1_HUMAN,tr|H0YBD7|H0YBD7_HUMAN,tr|H0YB39|H0YB39_HUMAN,tr|H0YBG7|H0YBG7_HUMAN,tr|E9PCY7|E9PCY7_HUMAN,tr|G8JLB6|G8JLB6_HUMAN" 7 1995.969 1.61 57474 25790 3 1995.976521 666.3303 Heterogeneous nuclear ribonucleoprotein F OS=Homo sapiens OX=9606 GN=HNRNPF PE=1 SV=3 4.37 3998.7 - 447267 - - - 3.7476 - 2.883 0.614 - 169.8 1 2 0 0.0075 17 0 0 0 2.79E+06 1.73E+06 - - - 8.0583 1 221125_WJC_METTL3_EV_vs_WT_F04.25791.25791.4 2.25E-12 26/240 R.MR[166.11]PGVAC[160.03]SVSQAQK[136.11]DELILEGNDIELVSNSAALIQQATTVK[136.11].N "sp|P32969|RL9_HUMAN,tr|H0Y9V9|H0Y9V9_HUMAN,tr|A0A2R8Y5Y7|A0A2R8Y5Y7_HUMAN" 3 4409.2781 0.76 57475 25791 4 4409.29266 1103.3268 60S ribosomal protein L9 OS=Homo sapiens OX=9606 GN=RPL9 PE=1 SV=1 4.51 3998.8 - 417657 - - - 3.3087 - 4.439 0.755 - 330.2 1 2 1 0.0146 41 0 0 0 1.70E+06 2.24E+06 - - - 6.2216 1 221125_WJC_METTL3_EV_vs_WT_F04.25792.25792.4 5.89E-21 26/240 R.MRPGVAC[160.03]SVSQAQKDELILEGNDIELVSNSAALIQQATTVK.N "sp|P32969|RL9_HUMAN,tr|H0Y9V9|H0Y9V9_HUMAN,tr|A0A2R8Y5Y7|A0A2R8Y5Y7_HUMAN" 3 4383.2414 0.76 57476 25792 4 4383.256408 1096.8176 60S ribosomal protein L9 OS=Homo sapiens OX=9606 GN=RPL9 PE=1 SV=1 4.51 3998.9 - 355835 - - - 3.4237 - 4.709 0.731 - 357.7 1 2 1 0.015 41 0 0 0 1.70E+06 2.24E+06 - - - 6.0296 1 221125_WJC_METTL3_EV_vs_WT_F04.25794.25794.4 5.89E-13 21/144 K.VEESGEHVILGTGELYLDC[160.03]VMHDLR.K sp|Q15029|U5S1_HUMAN 1 2870.3579 1.14 57478 25794 4 2870.368405 718.5967 116 kDa U5 small nuclear ribonucleoprotein component OS=Homo sapiens OX=9606 GN=EFTUD2 PE=1 SV=1 4.35 3999.2 - 320110 - - - 3.6668 - 3.992 0.703 - 279.4 1 2 0 0.0105 25 0 0 0 1.58E+06 1.38E+06 - - - 5.7824 0.9999 221125_WJC_METTL3_EV_vs_WT_F04.25796.25796.3 1.49E-05 14/84 R.EISESTPVEEVEALFKGDNLPK.F sp|Q92615|LAR4B_HUMAN 1 2430.2166 1.19 57480 25796 3 2430.220864 811.0795 La-related protein 4B OS=Homo sapiens OX=9606 GN=LARP4B PE=1 SV=3 4.14 3999.5 - 216149 - - - 1.7538 - 2.831 0.558 - 125.8 1 2 1 0.0043 22 0 0 0 6.58E+06 5.52E+06 - - - 7.2271 0.9999 221125_WJC_METTL3_EV_vs_WT_F04.25798.25798.4 4.03E-07 10/126 R.KPLVIIAEDVDGEALSTLVLNR.L "sp|P10809|CH60_HUMAN,tr|A0A7I2V2X6|A0A7I2V2X6_HUMAN,tr|A0A7I2YQK6|A0A7I2YQK6_HUMAN,tr|A0A7I2V599|A0A7I2V599_HUMAN,tr|A0A7I2YQ71|A0A7I2YQ71_HUMAN,tr|A0A7I2V5M1|A0A7I2V5M1_HUMAN,tr|A0A7I2V5K3|A0A7I2V5K3_HUMAN" 7 2364.3264 1.95 57482 25798 4 2364.336128 592.0889 "60 kDa heat shock protein, mitochondrial OS=Homo sapiens OX=9606 GN=HSPD1 PE=1 SV=2" 4.32 3999.7 - 126001 - - - 4.1031 - 2.16 0.57 - 59 1 2 0 0.0097 22 0 0 0 9.87E+05 5.05E+05 - - - 4.4366 1 221125_WJC_METTL3_EV_vs_WT_F04.25802.25802.3 1.13E-10 25/104 K.EIAEAYLGYPVTNAVITVPAYFNDSQR[166.11].Q "sp|P0DMV8|HS71A_HUMAN,sp|P0DMV9|HS71B_HUMAN,tr|A0A0G2JIW1|A0A0G2JIW1_HUMAN" 3 3010.4952 0.001 57484 25802 3 3010.504854 1004.5057 Heat shock 70 kDa protein 1A OS=Homo sapiens OX=9606 GN=HSPA1A PE=1 SV=1 4.14 4000.3 - 678556 - - - 3.2158 - 5.113 0.68 - 333.2 1 2 0 0.0097 27 0 0 0 0.00E+00 8.68E+06 - - - 9.8728 1 221125_WJC_METTL3_EV_vs_WT_F04.25803.25803.4 1.52E-12 18/150 R.DLDELSRYPEDKITPENLPQILLQLK.R "sp|P43243|MATR3_HUMAN,tr|A8MXP9|A8MXP9_HUMAN,tr|D6R991|D6R991_HUMAN,tr|A0A0R4J2E8|A0A0R4J2E8_HUMAN,tr|D6REM6|D6REM6_HUMAN" 5 3079.6441 1.38 57485 25803 4 3079.660784 770.9183 Matrin-3 OS=Homo sapiens OX=9606 GN=MATR3 PE=1 SV=2 4.3 4000.4 - 848438 - - - 5.4071 - 3.33 0.718 - 169.3 1 2 2 0.0167 26 0 0 0 3.86E+07 2.80E+07 - - - 5.8503 1 221125_WJC_METTL3_EV_vs_WT_F04.25805.25805.3 1.32E-11 21/84 R.EISESTPVEEVEALFK[136.11]GDNLPK[136.11].F sp|Q92615|LAR4B_HUMAN 1 2446.245 1.19 57487 25805 3 2446.257156 816.4223 La-related protein 4B OS=Homo sapiens OX=9606 GN=LARP4B PE=1 SV=3 4.14 4000.7 - 427919 - - - 4.9684 - 3.762 0.677 - 363.8 1 2 1 0.0122 22 0 0 0 6.58E+06 5.52E+06 - - - 9.2258 0.9999 221125_WJC_METTL3_EV_vs_WT_F04.25806.25806.3 4.37E-07 19/80 K.K[136.11]TSQIGESFEEILEETVISTK[136.11].K sp|Q16352|AINX_HUMAN 1 2383.2341 1.15 57488 25806 3 2383.241953 795.4186 Alpha-internexin OS=Homo sapiens OX=9606 GN=INA PE=1 SV=2 4.33 4000.8 - 413555 - - - 3.2938 - 3.56 0.524 - 437 1 2 0 0.0078 21 0 0 0 2.97E+06 2.59E+06 - - - 7.4241 1 221125_WJC_METTL3_EV_vs_WT_F04.25808.25808.4 1.63E-10 25/186 K.PVTTPEEIAQVATISANGDKEIGNIISDAMKK.V "sp|P10809|CH60_HUMAN,tr|A0A7I2V599|A0A7I2V599_HUMAN,tr|E7EXB4|E7EXB4_HUMAN,tr|A0A7I2YQ71|A0A7I2YQ71_HUMAN,tr|E7ESH4|E7ESH4_HUMAN,tr|A0A7I2V5M1|A0A7I2V5M1_HUMAN,tr|A0A7I2V5K3|A0A7I2V5K3_HUMAN,tr|A0A7I2V369|A0A7I2V369_HUMAN" 8 3339.7232 1.33 57490 25808 4 3339.750127 835.9381 "60 kDa heat shock protein, mitochondrial OS=Homo sapiens OX=9606 GN=HSPD1 PE=1 SV=2" 4.51 4001.1 - 181870 - - - 8.0665 - 5.483 0.649 - 409.7 1 1 1 0.0269 32 0 0 0 1.21E+07 9.07E+06 - - - 5.3812 0.9998 221125_WJC_METTL3_EV_vs_WT_F04.25810.25810.4 3.07E-05 19/198 R.GPPPSGIATLVSGIAGGAIPGQAPGSVPGPGLVK.D "tr|A0A804CDA6|A0A804CDA6_HUMAN,tr|E7EX90|E7EX90_HUMAN" 2 2975.6444 1.02 57492 25810 4 2975.658638 744.9184 Dynactin subunit 1 OS=Homo sapiens OX=9606 GN=DCTN1 PE=4 SV=1 8.75 4001.3 - 156457 - - - 4.7825 - 3.117 0.602 - 106.6 1 2 0 0.0142 34 0 0 0 3.93E+05 3.85E+05 - - - 4.8009 0.9996 221125_WJC_METTL3_EV_vs_WT_F04.25811.25811.3 1.16E-08 17/88 K.SINPDEAVAYGAAVQAAILSGDK[136.11].S "sp|P11142|HSP7C_HUMAN,tr|E9PNE6|E9PNE6_HUMAN,tr|A8K7Q2|A8K7Q2_HUMAN,tr|E9PKE3|E9PKE3_HUMAN" 4 2267.1525 0.22 57493 25811 3 2267.166205 756.7248 Heat shock cognate 71 kDa protein OS=Homo sapiens OX=9606 GN=HSPA8 PE=1 SV=1 4.03 4001.5 - 141505 - - - 6.0486 - 3.33 0.607 - 299.6 1 2 0 0.0137 23 0 0 0 5.32E+05 2.45E+06 - - - 8.1258 0.8002 221125_WJC_METTL3_EV_vs_WT_F04.25814.25814.4 0.000104 11/174 K.IVKPNGEKPDEFESGISQALLELEMNSDLK.A "sp|P62081|RS7_HUMAN,tr|B5MCP9|B5MCP9_HUMAN,tr|A0A2R8Y623|A0A2R8Y623_HUMAN" 3 3329.6701 0.83 57495 25814 4 3330.668665 833.4248 40S ribosomal protein S7 OS=Homo sapiens OX=9606 GN=RPS7 PE=1 SV=1 4.25 4001.9 - 1.53E+06 - - - 299.9024 - 2.492 0.234 - 60.5 1 2 0 0.9986 30 0 0 0 7.58E+06 9.17E+06 - - - 1.2655 1 221125_WJC_METTL3_EV_vs_WT_F04.25820.25820.3 4.89E-11 21/116 K.KVDSSVLGSLSSVPLTGFSFSPGNSSLFGK.D sp|Q9UKX7|NUP50_HUMAN 1 3000.5444 -1 57500 25820 3 3000.554512 1001.1887 Nuclear pore complex protein Nup50 OS=Homo sapiens OX=9606 GN=NUP50 PE=1 SV=2 8.59 4002.7 - 576615 - - - 3.3641 - 3.847 0.597 - 279.5 1 2 0 0.0101 30 0 0 0 0.00E+00 0.00E+00 - - - 8.2928 1 221125_WJC_METTL3_EV_vs_WT_F04.25827.25827.3 0.00335 Sep-60 K.K[136.11]VSQEILELLNTTTAK[136.11].E "sp|Q86U44|MTA70_HUMAN,tr|H0YFV6|H0YFV6_HUMAN" 2 1803.0324 0 57505 25827 3 1803.035258 602.0181 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 6.14 4003.6 - 158366 - - - 1.5685 - 2.221 0.587 - 140.9 1 2 0 0.0028 16 0 0 0 5.50E+04 3.88E+07 - - - 7.1311 1 221125_WJC_METTL3_EV_vs_WT_F04.25829.25829.4 6.94E-10 22/150 R.DLDELSR[166.11]YPEDK[136.11]ITPENLPQILLQLK[136.11].R "sp|P43243|MATR3_HUMAN,tr|A8MXP9|A8MXP9_HUMAN,tr|D6R991|D6R991_HUMAN,tr|A0A0R4J2E8|A0A0R4J2E8_HUMAN,tr|D6REM6|D6REM6_HUMAN" 5 3105.6808 1.38 57506 25829 4 3105.688708 777.4275 Matrin-3 OS=Homo sapiens OX=9606 GN=MATR3 PE=1 SV=2 4.3 4003.8 - 3.80E+06 - - - 2.5457 - 3.601 0.721 - 222 1 2 2 0.0079 26 0 0 0 3.86E+07 2.80E+07 - - - 5.9035 0.9998 221125_WJC_METTL3_EV_vs_WT_F04.25830.25830.4 1.53E-05 19/150 K.IGAVEEELNRVTELFMDNKNELDQC[160.03]K.S "sp|P52732|KIF11_HUMAN,tr|A0A7I2YQY4|A0A7I2YQY4_HUMAN,tr|A0A7I2V3A9|A0A7I2V3A9_HUMAN,tr|A0A7I2V3V3|A0A7I2V3V3_HUMAN" 4 3093.4747 1.75 57507 25830 4 3093.484502 774.376 Kinesin-like protein KIF11 OS=Homo sapiens OX=9606 GN=KIF11 PE=1 SV=2 4.25 4003.9 - 898883 - - - 3.1683 - 3.73 0.614 - 236.1 1 2 2 0.0098 26 0 0 0 3.97E+06 2.27E+06 - - - 4.9828 1 221125_WJC_METTL3_EV_vs_WT_F04.25831.25831.3 5.84E-14 25/100 R.DLDELSR[166.11]YPEDK[136.11]ITPENLPQILLQLK[136.11].R "sp|P43243|MATR3_HUMAN,tr|A8MXP9|A8MXP9_HUMAN,tr|D6R991|D6R991_HUMAN,tr|A0A0R4J2E8|A0A0R4J2E8_HUMAN,tr|D6REM6|D6REM6_HUMAN" 5 3105.6808 0.96 57508 25831 3 3105.687655 1036.2342 Matrin-3 OS=Homo sapiens OX=9606 GN=MATR3 PE=1 SV=2 4.3 4004.1 - 552118 - - - 2.2066 - 4.764 0.716 - 548.2 1 2 2 0.0069 26 0 0 0 4.08E+06 4.24E+06 - - - 10.1123 0.9998 221125_WJC_METTL3_EV_vs_WT_F04.25833.25833.4 7.97E-11 17/138 R.VHTVEDYQAIVDAEWNILYDKLEK.L sp|Q99832|TCPH_HUMAN 1 2890.4389 0.33 57510 25833 4 2890.448177 723.617 T-complex protein 1 subunit eta OS=Homo sapiens OX=9606 GN=CCT7 PE=1 SV=2 4.29 4004.3 - 352888 - - - 3.213 - 3.985 0.611 - 160.6 1 2 1 0.0093 24 0 0 0 1.13E+06 3.44E+06 - - - 4.9853 1 221125_WJC_METTL3_EV_vs_WT_F04.25838.25838.4 7.93E-12 25/144 K.NYSPYYNTIDDLKDQIVDLTVGNNK.T sp|P35527|K1C9_HUMAN 1 2901.4032 787.28 57513 25838 4 2901.406753 726.3581 "Keratin, type I cytoskeletal 9 OS=Homo sapiens OX=9606 GN=KRT9 PE=1 SV=3" 4.14 4004.9 - 6.59E+06 - - - 1.2132 - 3.391 0.631 - 298.4 1 2 1 0.0035 25 0 0 0 1.79E+08 2.28E+05 - - - 5.1057 1 221125_WJC_METTL3_EV_vs_WT_F04.25839.25839.4 7.88E-15 34/186 K.PVTTPEEIAQVATISANGDK[136.11]EIGNIISDAMK[136.11]K[136.11].V "sp|P10809|CH60_HUMAN,tr|A0A7I2V599|A0A7I2V599_HUMAN,tr|E7EXB4|E7EXB4_HUMAN,tr|A0A7I2YQ71|A0A7I2YQ71_HUMAN,tr|E7ESH4|E7ESH4_HUMAN,tr|A0A7I2V5M1|A0A7I2V5M1_HUMAN,tr|A0A7I2V5K3|A0A7I2V5K3_HUMAN,tr|A0A7I2V369|A0A7I2V369_HUMAN" 8 3363.7658 1.33 57514 25839 4 3363.765732 841.9487 "60 kDa heat shock protein, mitochondrial OS=Homo sapiens OX=9606 GN=HSPD1 PE=1 SV=2" 4.51 4005 - 1.64E+06 - - - -0.0164 - 6.113 0.636 - 784 1 1 1 -0.0001 32 0 0 0 1.21E+07 9.07E+06 - - - 5.3084 0.9999 221125_WJC_METTL3_EV_vs_WT_F04.25840.25840.4 0.000318 14/156 R.QSPEHNLTHPELSVAVEMLSSVALINR[166.11].A "sp|P46940|IQGA1_HUMAN,tr|A0A0J9YXZ5|A0A0J9YXZ5_HUMAN" 2 2980.5316 1.06 57515 25840 4 2980.529227 746.1402 Ras GTPase-activating-like protein IQGAP1 OS=Homo sapiens OX=9606 GN=IQGAP1 PE=1 SV=1 5.33 4005.2 - 728490 - - - -0.7881 - 2.9 0.461 - 129.9 1 2 0 -0.0023 27 0 0 0 4.56E+06 4.31E+06 - - - 3.571 1 221125_WJC_METTL3_EV_vs_WT_F04.25841.25841.3 1.48E-12 25/100 R.DLDELSRYPEDKITPENLPQILLQLK.R "sp|P43243|MATR3_HUMAN,tr|A8MXP9|A8MXP9_HUMAN,tr|D6R991|D6R991_HUMAN,tr|A0A0R4J2E8|A0A0R4J2E8_HUMAN,tr|D6REM6|D6REM6_HUMAN" 5 3079.6441 0.96 57516 25841 3 3079.657523 1027.5553 Matrin-3 OS=Homo sapiens OX=9606 GN=MATR3 PE=1 SV=2 4.3 4005.3 - 703340 - - - 4.3482 - 3.88 0.659 - 424.7 1 2 2 0.0134 26 0 0 0 4.08E+06 4.24E+06 - - - 9.0028 0.9999 221125_WJC_METTL3_EV_vs_WT_F04.25842.25842.4 1.34E-06 18/180 K.AFAMIIDKLEEDINSSMTNSTAASRPPVTLR.L sp|Q15365|PCBP1_HUMAN 1 3377.6959 0.52 57517 25842 4 3377.69529 845.4313 Poly(rC)-binding protein 1 OS=Homo sapiens OX=9606 GN=PCBP1 PE=1 SV=2 4.78 4005.4 - 640391 - - - -0.1886 - 3.326 0.519 - 133 1 2 1 -0.0006 31 0 0 0 2.82E+06 5.41E+06 - - - 4.1084 1 221125_WJC_METTL3_EV_vs_WT_F04.25844.25844.3 2.34E-07 14/84 R.TLTAVHDAILEDLVFPSEIVGK[136.11].R "sp|P62081|RS7_HUMAN,tr|B5MCP9|B5MCP9_HUMAN,tr|A0A2R8Y623|A0A2R8Y623_HUMAN" 3 2374.2875 0.74 57519 25844 3 2374.289326 792.4365 40S ribosomal protein S7 OS=Homo sapiens OX=9606 GN=RPS7 PE=1 SV=1 4.31 4005.7 - 404439 - - - 0.7569 - 3.111 0.591 - 213.6 1 2 0 0.0018 22 0 0 0 2.93E+06 3.98E+06 - - - 7.8193 1 221125_WJC_METTL3_EV_vs_WT_F04.25847.25847.3 1.39E-09 19/96 K.NYSPYYNTIDDLKDQIVDLTVGNNK.T sp|P35527|K1C9_HUMAN 1 2901.4032 999 57520 25847 3 2901.401671 968.1417 "Keratin, type I cytoskeletal 9 OS=Homo sapiens OX=9606 GN=KRT9 PE=1 SV=3" 4.14 4006.1 - 9.90E+07 - - - -0.5384 - 3.835 0.684 - 244.8 1 2 1 -0.0016 25 0 0 0 8.27E+08 0.00E+00 - - - 9.2579 1 221125_WJC_METTL3_EV_vs_WT_F04.25850.25850.2 5.47E-14 29/48 K.NYSPYYNTIDDLKDQIVDLTVGNNK.T sp|P35527|K1C9_HUMAN 1 2901.4032 999 57523 25850 2 2901.40142 1451.7089 "Keratin, type I cytoskeletal 9 OS=Homo sapiens OX=9606 GN=KRT9 PE=1 SV=3" 4.14 4006.4 - 718413 - - - -0.6249 - 4.829 0.772 - 1579.2 1 2 1 -0.0018 25 0 0 0 1.54E+07 0.00E+00 - - - 8.6137 1 221125_WJC_METTL3_EV_vs_WT_F04.25851.25851.3 7.13E-10 21/84 R.TLTAVHDAILEDLVFPSEIVGK.R "sp|P62081|RS7_HUMAN,tr|B5MCP9|B5MCP9_HUMAN,tr|A0A2R8Y623|A0A2R8Y623_HUMAN" 3 2366.2733 0.74 57524 25851 3 2366.272217 789.7651 40S ribosomal protein S7 OS=Homo sapiens OX=9606 GN=RPS7 PE=1 SV=1 4.31 4006.5 - 627442 - - - -0.4699 - 3.357 0.627 - 521.7 1 2 0 -0.0011 22 0 0 0 2.93E+06 3.98E+06 - - - 8.4013 1 221125_WJC_METTL3_EV_vs_WT_F04.25856.25856.4 2.01E-14 41/138 K.VIHDNFGIVEGLMTTVHAITATQK[136.11].T "sp|P04406|G3P_HUMAN,tr|E7EUT5|E7EUT5_HUMAN" 2 2602.3669 -1 57527 25856 4 2602.363681 651.599 Glyceraldehyde-3-phosphate dehydrogenase OS=Homo sapiens OX=9606 GN=GAPDH PE=1 SV=3 5.99 4007 - 1.76E+07 - - - -1.2208 - 5.925 0.613 - 1255.5 1 2 0 -0.0032 24 0 0 0 0.00E+00 0.00E+00 - - - 5.1317 1 221125_WJC_METTL3_EV_vs_WT_F04.25857.25857.3 1.33E-14 48/92 K.VIHDNFGIVEGLMTTVHAITATQK.T "sp|P04406|G3P_HUMAN,tr|E7EUT5|E7EUT5_HUMAN" 2 2594.3527 -1 57528 25857 3 2594.350814 865.7915 Glyceraldehyde-3-phosphate dehydrogenase OS=Homo sapiens OX=9606 GN=GAPDH PE=1 SV=3 5.99 4007.1 - 6.51E+06 - - - -0.7108 - 7.359 0.707 - 3882.3 1 2 0 -0.0018 24 0 0 0 0.00E+00 0.00E+00 - - - 11.0576 1 221125_WJC_METTL3_EV_vs_WT_F04.25858.25858.3 4.37E-14 42/92 K.VIHDNFGIVEGLMTTVHAITATQK[136.11].T "sp|P04406|G3P_HUMAN,tr|E7EUT5|E7EUT5_HUMAN" 2 2602.3669 0.34 57529 25858 3 2602.363599 868.4629 Glyceraldehyde-3-phosphate dehydrogenase OS=Homo sapiens OX=9606 GN=GAPDH PE=1 SV=3 5.99 4007.2 - 6.27E+06 - - - -1.2523 - 7.235 0.691 - 3037.3 1 2 0 -0.0033 24 0 0 0 6.98E+06 2.08E+07 - - - 10.8393 0.951 221125_WJC_METTL3_EV_vs_WT_F04.26564.26564.2 2.86 12-May K.EQSIVEK[136.11].F "sp|Q86U44|MTA70_HUMAN,tr|H0YFV6|H0YFV6_HUMAN" 2 839.448 0.04 57618 26564 2 839.448721 420.7313 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 4.53 4136.5 - 401208 - - - 0.8613 - 1.216 0.025 - 165.4 2 2 0 0.0007 7 0 0 0 3.43E+04 8.44E+05 - - - -0.2894 1 221125_WJC_METTL3_EV_vs_WT_F04.26569.26569.3 1.14E-12 18/116 K.DMAIATGGAVFGEEGLTLNLEDVQPHDLGK.V "sp|P10809|CH60_HUMAN,tr|A0A7I2V2X6|A0A7I2V2X6_HUMAN,tr|A0A7I2YQK6|A0A7I2YQK6_HUMAN,tr|A0A7I2V599|A0A7I2V599_HUMAN" 4 3096.5074 -1 57621 26569 3 3096.520789 1033.1764 "60 kDa heat shock protein, mitochondrial OS=Homo sapiens OX=9606 GN=HSPD1 PE=1 SV=2" 4.01 4137.1 - 2.12E+06 - - - 4.33 - 3.798 0.692 - 176.7 1 2 0 0.0134 30 0 0 0 0.00E+00 0.00E+00 - - - 9.3215 0.9956 221125_WJC_METTL3_EV_vs_WT_F04.27003.27003.2 0.00631 22-Apr K.TEELEEESFPER.S "sp|Q9Y2W1|TR150_HUMAN,tr|A0A3B3ITZ9|A0A3B3ITZ9_HUMAN" 2 1493.6522 3.93 57636 27003 2 1493.657514 747.8334 Thyroid hormone receptor-associated protein 3 OS=Homo sapiens OX=9606 GN=THRAP3 PE=1 SV=2 3.9 4222.3 - 19291.6 - - - 3.5691 - 1.133 0.463 - 48 1 2 0 0.0053 12 0 0 0 8.67E+05 2.20E+05 - - - 2.7876 0.9809 221125_WJC_METTL3_EV_vs_WT_F05.02340.02340.2 0.0232 14-Sep R.VGSAAQTR[166.11].A sp|P25705|ATPA_HUMAN 1 798.4223 1.22 57677 2340 2 798.41774 400.2184 "ATP synthase subunit alpha, mitochondrial OS=Homo sapiens OX=9606 GN=ATP5F1A PE=1 SV=1" 9.72 1183.5 - 192534 - - - -5.7564 - 1.846 0.266 - 253.3 1 2 0 -0.0046 8 0 0 0 4.25E+08 3.49E+08 - - - 2.8531 0.9964 221125_WJC_METTL3_EV_vs_WT_F05.02344.02344.2 0.00805 14-Oct R.VGSAAQTR.A sp|P25705|ATPA_HUMAN 1 788.4141 1.22 57678 2344 2 788.411076 395.2143 "ATP synthase subunit alpha, mitochondrial OS=Homo sapiens OX=9606 GN=ATP5F1A PE=1 SV=1" 9.72 1184.1 - 552680 - - - -3.7924 - 1.775 0.318 - 298.2 1 2 0 -0.003 8 0 0 0 4.25E+08 3.49E+08 - - - 3.1194 0.9056 221125_WJC_METTL3_EV_vs_WT_F05.02550.02550.2 2.8 12-Jul K.LVNNGEK[136.11].L sp|Q15393|SF3B3_HUMAN 1 780.4221 0.99 57730 2550 2 780.419038 391.2183 Splicing factor 3B subunit 3 OS=Homo sapiens OX=9606 GN=SF3B3 PE=1 SV=4 6 1214.5 - 513898 - - - -3.9466 - 1.234 0.111 - 147.3 1 2 0 -0.0031 7 0 0 0 1.24E+07 1.25E+07 - - - 0.5261 0.9844 221125_WJC_METTL3_EV_vs_WT_F05.02588.02588.2 0.175 14-Jul K.VVDNTTAK[136.11].E "sp|Q9H0U4|RAB1B_HUMAN,sp|Q92928|RAB1C_HUMAN,tr|E9PLD0|E9PLD0_HUMAN" 3 854.4589 1.18 57739 2588 2 854.455172 428.2367 Ras-related protein Rab-1B OS=Homo sapiens OX=9606 GN=RAB1B PE=1 SV=1 5.81 1220.3 - 147334 - - - -4.3595 - 1.223 0.338 - 162.6 1 2 0 -0.0037 8 0 0 0 1.95E+08 1.65E+08 - - - 2.1434 0.9897 221125_WJC_METTL3_EV_vs_WT_F05.02602.02602.2 0.00118 14-Aug K.VVDNTTAK.E "sp|Q9H0U4|RAB1B_HUMAN,sp|Q92928|RAB1C_HUMAN,tr|E9PLD0|E9PLD0_HUMAN" 3 846.4447 1.18 57744 2602 2 846.440775 424.2296 Ras-related protein Rab-1B OS=Homo sapiens OX=9606 GN=RAB1B PE=1 SV=1 5.81 1222.2 - 2.20E+06 - - - -4.6335 - 1.376 0.364 - 165.7 1 2 0 -0.0039 8 0 0 0 1.95E+08 1.65E+08 - - - 2.6909 0.9572 221125_WJC_METTL3_EV_vs_WT_F05.02634.02634.2 0.135 12-Jul K.ITDSEDK[136.11].A "sp|P35613|BASI_HUMAN,tr|A0A7P0T8A7|A0A7P0T8A7_HUMAN,tr|A0A087WUV8|A0A087WUV8_HUMAN,tr|A0A7P0TA85|A0A7P0TA85_HUMAN,tr|A0A7P0TB04|A0A7P0TB04_HUMAN,tr|R4GMX5|R4GMX5_HUMAN,tr|I3L192|I3L192_HUMAN" 7 814.38 2.03 57757 2634 2 814.376257 408.1973 Basigin OS=Homo sapiens OX=9606 GN=BSG PE=1 SV=2 4.03 1226.7 - 1.50E+06 - - - -4.5691 - 1.415 0.176 - 140 1 2 0 -0.0037 7 0 0 0 1.09E+08 5.38E+07 - - - 1.4397 0.9761 221125_WJC_METTL3_EV_vs_WT_F05.02650.02650.2 0.152 14-Aug K.TVESAEGK.S "sp|P82094|TMF1_HUMAN,tr|F8WF45|F8WF45_HUMAN,tr|A0A2R8Y7M0|A0A2R8Y7M0_HUMAN" 3 819.3974 1.58 57762 2650 2 819.393357 410.706 TATA element modulatory factor OS=Homo sapiens OX=9606 GN=TMF1 PE=1 SV=2 4.53 1229.1 - 1.19E+06 - - - -4.9488 - 1.538 0.243 - 201.8 1 2 0 -0.0041 8 0 0 0 1.15E+08 7.28E+07 - - - 2.1328 0.9558 221125_WJC_METTL3_EV_vs_WT_F05.02658.02658.2 2.35 12-Apr K.EPASYGR[166.11].Q "sp|Q9Y2H5|PKHA6_HUMAN,tr|A0A1B0GUN5|A0A1B0GUN5_HUMAN,tr|Q5VTI5|Q5VTI5_HUMAN" 3 788.3692 0.58 57765 2658 2 788.36957 395.1919 Pleckstrin homology domain-containing family A member 6 OS=Homo sapiens OX=9606 GN=PLEKHA6 PE=1 SV=4 6.1 1230.1 - 1.38E+06 - - - 0.4224 - 1.001 0.129 - 46.5 5 2 0 0.0003 7 0 0 0 2.96E+07 5.13E+07 - - - -0.3154 0.766 221125_WJC_METTL3_EV_vs_WT_F05.02661.02661.2 4.25 14-Jul K.TVESAEGK[136.11].S "sp|P82094|TMF1_HUMAN,tr|F8WF45|F8WF45_HUMAN,tr|A0A2R8Y7M0|A0A2R8Y7M0_HUMAN" 3 827.4116 1.59 57766 2661 2 827.408318 414.7131 TATA element modulatory factor OS=Homo sapiens OX=9606 GN=TMF1 PE=1 SV=2 4.53 1230.5 - 2.52E+06 - - - -3.9811 - 1.102 0.07 - 103 1 2 0 -0.0033 8 0 0 0 1.15E+08 7.26E+07 - - - -0.1501 0.9228 221125_WJC_METTL3_EV_vs_WT_F05.02663.02663.2 0.176 14-Jun R.LASGSTDR.H sp|Q9GZL7|WDR12_HUMAN 1 805.393 0.99 57767 2663 2 805.389926 403.7038 Ribosome biogenesis protein WDR12 OS=Homo sapiens OX=9606 GN=WDR12 PE=1 SV=2 5.84 1230.7 - 2.93E+06 - - - -3.8118 - 1.287 0.109 - 93.3 1 2 0 -0.0031 8 0 0 0 7.08E+07 7.14E+07 - - - 0.6061 0.7705 221125_WJC_METTL3_EV_vs_WT_F05.02665.02665.2 1.55 12-Jun K.LAEEHSS.- sp|P06576|ATPB_HUMAN 1 771.3399 - 57768 2665 2 771.337347 386.6772 "ATP synthase subunit beta, mitochondrial OS=Homo sapiens OX=9606 GN=ATP5F1B PE=1 SV=3" 4.51 1231 - 4.93E+06 - - - -3.3072 - 1.068 0.06 - 85.5 2 2 0 -0.0026 7 0 0 0 - - - - - -0.4427 0.9914 221125_WJC_METTL3_EV_vs_WT_F05.02667.02667.2 0.00552 14-Jul R.APVSQAAK[136.11].F sp|Q01780|EXOSX_HUMAN 1 778.4429 1.2 57770 2667 2 778.440033 390.2287 Exosome component 10 OS=Homo sapiens OX=9606 GN=EXOSC10 PE=1 SV=2 8.8 1231.1 - 1.69E+06 - - - -3.6226 - 1.414 0.285 - 150.6 1 2 0 -0.0028 8 0 0 0 8.89E+07 7.42E+07 - - - 2.1899 0.973 221125_WJC_METTL3_EV_vs_WT_F05.02680.02680.2 0.455 12-Aug K.SEEVATK.E "sp|P07197|NFM_HUMAN,tr|E7ESP9|E7ESP9_HUMAN" 2 762.3759 0.23 57773 2680 2 762.3728 382.1953 Neurofilament medium polypeptide OS=Homo sapiens OX=9606 GN=NEFM PE=1 SV=3 4.53 1233.1 - 895825 - - - -4.1305 - 1.515 0.163 - 354.3 1 2 0 -0.0031 7 0 0 0 2.24E+07 9.65E+07 - - - 1.5602 0.9465 221125_WJC_METTL3_EV_vs_WT_F05.02714.02714.2 0.197 16-Aug R.LESSGAGGR[166.11].R sp|Q15773|MLF2_HUMAN 1 842.4122 1.52 57788 2714 2 842.40815 422.2134 Myeloid leukemia factor 2 OS=Homo sapiens OX=9606 GN=MLF2 PE=1 SV=1 6 1237.5 - 560820 - - - -4.7661 - 1.586 0.135 - 148.4 1 2 0 -0.004 9 0 0 0 2.26E+07 1.49E+07 - - - 1.3712 0.9929 221125_WJC_METTL3_EV_vs_WT_F05.02722.02722.2 0.0395 14-Aug K.TVDGPSGK[136.11].L "sp|P04406|G3P_HUMAN,tr|E7EUT5|E7EUT5_HUMAN" 2 767.3905 0.98 57790 2722 2 767.388464 384.7025 Glyceraldehyde-3-phosphate dehydrogenase OS=Homo sapiens OX=9606 GN=GAPDH PE=1 SV=3 5.5 1238.7 - 2.79E+06 - - - -2.631 - 1.249 0.277 - 173.9 1 2 0 -0.002 8 0 0 0 3.44E+08 3.52E+08 - - - 1.7569 0.9786 221125_WJC_METTL3_EV_vs_WT_F05.02760.02760.2 0.0851 14-Jul R.AVAEEESK.G sp|Q969S3|ZN622_HUMAN 1 861.408 1.15 57803 2760 2 861.40475 431.7113 Zinc finger protein 622 OS=Homo sapiens OX=9606 GN=ZNF622 PE=1 SV=1 4.25 1244 - 1.46E+06 - - - -3.7462 - 1.268 0.24 - 143.4 1 2 0 -0.0032 8 0 0 0 2.51E+07 2.17E+07 - - - 1.5287 0.9857 221125_WJC_METTL3_EV_vs_WT_F05.02762.02762.2 0.0138 18-Oct R.ATGAAAAEAK[136.11].A "sp|Q8NE71|ABCF1_HUMAN,tr|Q5STZ8|Q5STZ8_HUMAN,tr|H0YGW7|H0YGW7_HUMAN" 3 867.4541 0.8 57804 2762 2 867.449682 434.7343 ATP-binding cassette sub-family F member 1 OS=Homo sapiens OX=9606 GN=ABCF1 PE=1 SV=2 6.05 1244.2 - 1.82E+06 - - - -5.1461 - 1.869 0.263 - 301.6 1 2 0 -0.0045 10 0 0 0 1.43E+08 1.78E+08 - - - 2.7278 0.9732 221125_WJC_METTL3_EV_vs_WT_F05.02764.02764.2 0.0286 18-Aug R.ATGAAAAEAK.A "sp|Q8NE71|ABCF1_HUMAN,tr|Q5STZ8|Q5STZ8_HUMAN,tr|H0YGW7|H0YGW7_HUMAN" 3 859.4399 0.8 57805 2764 2 859.43573 430.7272 ATP-binding cassette sub-family F member 1 OS=Homo sapiens OX=9606 GN=ABCF1 PE=1 SV=2 6.05 1244.4 - 2.04E+06 - - - -4.9055 - 1.54 0.239 - 139.6 1 2 0 -0.0042 10 0 0 0 1.43E+08 1.78E+08 - - - 2.0102 0.9294 221125_WJC_METTL3_EV_vs_WT_F05.02812.02812.2 0.62 12-Aug K.LAEEQQK.Q "sp|P17480|UBF1_HUMAN,tr|E9PKP7|E9PKP7_HUMAN,tr|H0YDH7|H0YDH7_HUMAN" 3 844.429 1.31 57814 2812 2 844.424724 423.2218 Nucleolar transcription factor 1 OS=Homo sapiens OX=9606 GN=UBTF PE=1 SV=1 4.53 1251.5 - 1.79E+06 - - - -5.1194 - 1.47 0.146 - 180 1 2 0 -0.0043 7 0 0 0 6.18E+07 4.74E+07 - - - 1.3387 0.9626 221125_WJC_METTL3_EV_vs_WT_F05.02814.02814.2 0.201 12-Jul K.LAEEQQK[136.11].Q "sp|P17480|UBF1_HUMAN,tr|E9PKP7|E9PKP7_HUMAN,tr|H0YDH7|H0YDH7_HUMAN" 3 852.4432 1.3 57815 2814 2 852.439733 427.2289 Nucleolar transcription factor 1 OS=Homo sapiens OX=9606 GN=UBTF PE=1 SV=1 4.53 1251.7 - 1.06E+06 - - - -4.1223 - 1.33 0.184 - 135.7 1 2 0 -0.0035 7 0 0 0 6.19E+07 4.75E+07 - - - 1.3025 0.9573 221125_WJC_METTL3_EV_vs_WT_F05.02837.02837.2 0.324 14-Jun R.SPGSQGVR.D sp|O43678|NDUA2_HUMAN 1 786.3984 2.04 57825 2837 2 786.396011 394.2065 NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 2 OS=Homo sapiens OX=9606 GN=NDUFA2 PE=1 SV=3 9.47 1254.7 - 1.36E+06 - - - -3.057 - 1.158 0.159 - 99.7 1 2 0 -0.0024 8 0 0 0 7.33E+07 3.59E+07 - - - 0.657 0.9901 221125_WJC_METTL3_EV_vs_WT_F05.02841.02841.2 0.0261 12-Jun K.C[160.03]DPDAAR[166.11].A sp|Q15181|IPYR_HUMAN 1 813.3315 0.59 57827 2841 2 813.329181 407.673 Inorganic pyrophosphatase OS=Homo sapiens OX=9606 GN=PPA1 PE=1 SV=2 4.21 1255.2 - 551018 - - - -2.8168 - 1.082 0.313 - 235.5 1 2 0 -0.0023 7 0 0 0 2.39E+07 4.02E+07 - - - 1.6018 0.9953 221125_WJC_METTL3_EV_vs_WT_F05.02848.02848.2 2.31 12-Aug K.DAEAVQK.F sp|Q15388|TOM20_HUMAN 1 759.3763 1.41 57831 2848 2 759.376027 380.6954 Mitochondrial import receptor subunit TOM20 homolog OS=Homo sapiens OX=9606 GN=TOMM20 PE=1 SV=1 4.37 1256.1 - 1.81E+06 - - - -0.3371 - 1.479 0.117 - 261.8 1 2 0 -0.0003 7 0 0 0 3.67E+08 2.61E+08 - - - 1.1451 0.989 221125_WJC_METTL3_EV_vs_WT_F05.02851.02851.2 0.843 14-Sep R.SPGSQGVR[166.11].D sp|O43678|NDUA2_HUMAN 1 796.4067 2.98 57832 2851 2 796.404111 399.2106 NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 2 OS=Homo sapiens OX=9606 GN=NDUFA2 PE=1 SV=3 9.47 1256.5 - 1.92E+06 - - - -3.232 - 1.678 0.156 - 249.6 1 2 0 -0.0026 8 0 0 0 1.42E+08 4.78E+07 - - - 1.7535 0.9675 221125_WJC_METTL3_EV_vs_WT_F05.02857.02857.2 1.03 14-Jul K.ATPAEEEK[136.11].T "sp|Q15269|PWP2_HUMAN,tr|A0A0B4J2E5|A0A0B4J2E5_HUMAN" 2 881.4222 1.23 57834 2857 2 881.420353 441.7184 Periodic tryptophan protein 2 homolog OS=Homo sapiens OX=9606 GN=PWP2 PE=2 SV=2 4.25 1257.3 - 384695 - - - -2.0694 - 1.12 0.133 - 138.4 1 2 0 -0.0018 8 0 0 0 5.54E+07 4.50E+07 - - - 0.3646 0.9647 221125_WJC_METTL3_EV_vs_WT_F05.02862.02862.2 0.512 14-Aug R.APSADTAR.S sp|Q9BUA3|SPNDC_HUMAN 1 787.3824 0.88 57837 2862 2 787.37798 394.6985 Spindlin interactor and repressor of chromatin-binding protein OS=Homo sapiens OX=9606 GN=SPINDOC PE=1 SV=3 5.88 1257.9 - 5.50E+06 - - - -5.6529 - 1.611 0.235 - 198.8 1 2 0 -0.0045 8 0 0 0 3.61E+08 4.08E+08 - - - 2.2135 0.9921 221125_WJC_METTL3_EV_vs_WT_F05.02879.02879.2 0.0908 12-Jul R.VGETETR.L "sp|P61962|DCAF7_HUMAN,tr|A0A087WWI6|A0A087WWI6_HUMAN" 2 790.3821 0.32 57841 2879 2 790.378964 396.1983 DDB1- and CUL4-associated factor 7 OS=Homo sapiens OX=9606 GN=DCAF7 PE=1 SV=1 4.53 1260.4 - 2.07E+07 - - - -3.9639 - 1.695 0.241 - 167.6 1 2 0 -0.0031 7 0 0 0 4.76E+08 1.51E+09 - - - 2.492 0.9847 221125_WJC_METTL3_EV_vs_WT_F05.02936.02936.2 0.711 14-Jul R.VPSSTAGR[166.11].V "sp|Q9Y6M1|IF2B2_HUMAN,tr|F8W930|F8W930_HUMAN" 2 783.4114 1.46 57857 2936 2 783.408589 392.713 Insulin-like growth factor 2 mRNA-binding protein 2 OS=Homo sapiens OX=9606 GN=IGF2BP2 PE=1 SV=2 9.72 1268.4 - 3.30E+06 - - - -3.6341 - 1.549 0.185 - 145.3 1 2 0 -0.0028 8 0 0 0 1.68E+08 1.15E+08 - - - 1.7263 0.9948 221125_WJC_METTL3_EV_vs_WT_F05.02946.02946.2 0.0314 14-Jul K.ITEGQAAK[136.11].K "sp|Q9BSV6|SEN34_HUMAN,tr|A0A590UJ73|A0A590UJ73_HUMAN,tr|E7EQB3|E7EQB3_HUMAN,tr|A0A0G2JNK5|A0A0G2JNK5_HUMAN,tr|A0A0G2JNL0|A0A0G2JNL0_HUMAN,tr|A0A590UJW4|A0A590UJW4_HUMAN,tr|B0V3J0|B0V3J0_HUMAN" 7 824.4483 1.42 57860 2946 2 824.444765 413.2314 tRNA-splicing endonuclease subunit Sen34 OS=Homo sapiens OX=9606 GN=TSEN34 PE=1 SV=1 6 1269.8 - 911563 - - - -4.3265 - 1.634 0.356 - 123.1 1 2 0 -0.0036 8 0 0 0 1.76E+08 1.24E+08 - - - 3.1502 0.9733 221125_WJC_METTL3_EV_vs_WT_F05.02949.02949.2 0.325 14-Jul K.ITEGQAAK.K "sp|Q9BSV6|SEN34_HUMAN,tr|A0A590UJ73|A0A590UJ73_HUMAN,tr|E7EQB3|E7EQB3_HUMAN,tr|A0A0G2JNK5|A0A0G2JNK5_HUMAN,tr|A0A0G2JNL0|A0A0G2JNL0_HUMAN,tr|A0A590UJW4|A0A590UJW4_HUMAN,tr|B0V3J0|B0V3J0_HUMAN" 7 816.4341 1.55 57862 2949 2 816.430687 409.2243 tRNA-splicing endonuclease subunit Sen34 OS=Homo sapiens OX=9606 GN=TSEN34 PE=1 SV=1 6 1270.2 - 2.12E+06 - - - -4.2196 - 1.447 0.198 - 117.5 1 2 0 -0.0034 8 0 0 0 1.76E+08 1.14E+08 - - - 1.6167 0.9985 221125_WJC_METTL3_EV_vs_WT_F05.02969.02969.2 0.0243 12-Jul K.LTATTQK.Q sp|P12270|TPR_HUMAN 1 761.4283 2.54 57869 2969 2 761.426521 381.7214 Nucleoprotein TPR OS=Homo sapiens OX=9606 GN=TPR PE=1 SV=3 8.75 1273.1 - 1.70E+06 - - - -2.3614 - 1.621 0.321 - 146.6 1 2 0 -0.0018 7 0 0 0 1.96E+08 7.70E+07 - - - 2.9419 0.9895 221125_WJC_METTL3_EV_vs_WT_F05.02978.02978.2 0.128 12-Jul R.LTEANQR.M sp|Q8TEQ6|GEMI5_HUMAN 1 830.4246 1.54 57872 2978 2 830.421922 416.2196 Gem-associated protein 5 OS=Homo sapiens OX=9606 GN=GEMIN5 PE=1 SV=3 6 1274.3 - 577135 - - - -3.261 - 1.432 0.221 - 164.8 1 2 0 -0.0027 7 0 0 0 2.53E+07 1.65E+07 - - - 1.8102 0.9843 221125_WJC_METTL3_EV_vs_WT_F05.03006.03006.2 0.154 12-Aug K.TAQQIAK[136.11].D "sp|P52756|RBM5_HUMAN,sp|P98175|RBM10_HUMAN" 2 766.4429 1.35 57882 3006 2 766.439825 384.2287 RNA-binding protein 5 OS=Homo sapiens OX=9606 GN=RBM5 PE=1 SV=2 8.41 1278.2 - 2.05E+06 - - - -3.9507 - 1.529 0.204 - 252.9 1 2 0 -0.003 7 0 0 0 2.75E+08 2.03E+08 - - - 1.8922 0.9994 221125_WJC_METTL3_EV_vs_WT_F05.03023.03023.2 0.00358 12-Oct K.TAQQIAK.D "sp|P52756|RBM5_HUMAN,sp|P98175|RBM10_HUMAN" 2 758.4287 1.35 57888 3023 2 758.427386 380.2216 RNA-binding protein 5 OS=Homo sapiens OX=9606 GN=RBM5 PE=1 SV=2 8.41 1280.6 - 9.97E+06 - - - -1.6706 - 1.76 0.358 - 376.1 1 2 0 -0.0013 7 0 0 0 2.75E+08 2.03E+08 - - - 3.476 0.9265 221125_WJC_METTL3_EV_vs_WT_F05.03042.03042.2 0.553 14-May R.EASDGEVR[166.11].R sp|Q8WXX5|DNJC9_HUMAN 1 871.3911 2.5 57895 3042 2 871.387556 436.7028 DnaJ homolog subfamily C member 9 OS=Homo sapiens OX=9606 GN=DNAJC9 PE=1 SV=1 4.14 1283.1 - 202882 - - - -4.0613 - 1.11 0.191 - 109.8 1 2 0 -0.0035 8 0 0 0 4.99E+07 1.99E+07 - - - 0.7654 0.9892 221125_WJC_METTL3_EV_vs_WT_F05.03051.03051.2 0.061 14-Jul R.EASDGEVR.R sp|Q8WXX5|DNJC9_HUMAN 1 861.3828 2.68 57899 3051 2 861.379877 431.6987 DnaJ homolog subfamily C member 9 OS=Homo sapiens OX=9606 GN=DNAJC9 PE=1 SV=1 4.14 1284.2 - 714885 - - - -3.4224 - 1.26 0.29 - 197.7 1 2 0 -0.0029 8 0 0 0 5.37E+07 2.01E+07 - - - 1.879 0.9952 221125_WJC_METTL3_EV_vs_WT_F05.03054.03054.2 0.00333 22-Jul R.FSSSGGGGGGGR.F sp|P35527|K1C9_HUMAN 1 981.4264 0.29 57900 3054 2 981.424312 491.7205 "Keratin, type I cytoskeletal 9 OS=Homo sapiens OX=9606 GN=KRT9 PE=1 SV=3" 9.75 1284.6 - 148123 - - - -2.1489 - 1.505 0.244 - 63.4 2 2 0 -0.0021 12 0 0 0 4.17E+06 1.45E+07 - - - 1.7837 0.9959 221125_WJC_METTL3_EV_vs_WT_F05.03075.03075.2 0.0681 14-Jul K.ASGNLETK.Y "sp|Q9Y277|VDAC3_HUMAN,tr|E5RHE1|E5RHE1_HUMAN,tr|E5RJN6|E5RJN6_HUMAN,tr|C9J536|C9J536_HUMAN,tr|E5RK27|E5RK27_HUMAN,tr|E5RFP6|E5RFP6_HUMAN,tr|E5RHZ6|E5RHZ6_HUMAN" 7 818.4134 0.57 57906 3075 2 818.410761 410.214 Voltage-dependent anion-selective channel protein 3 OS=Homo sapiens OX=9606 GN=VDAC3 PE=1 SV=1 6.05 1287.6 - 816080 - - - -3.2209 - 1.559 0.3 - 221.5 1 2 0 -0.0026 8 0 0 0 2.34E+08 4.08E+08 - - - 2.5952 0.9958 221125_WJC_METTL3_EV_vs_WT_F05.03082.03082.2 0.00813 12-Jun R.MC[160.03]PATQK[136.11].L sp|Q9H307|PININ_HUMAN 1 842.387 1.11 57908 3082 2 842.384448 422.2008 Pinin OS=Homo sapiens OX=9606 GN=PNN PE=1 SV=5 7.98 1288.6 - 999408 - - - -3.0236 - 1.396 0.317 - 169.6 1 2 0 -0.0025 7 0 0 0 5.65E+07 5.11E+07 - - - 2.4386 0.9969 221125_WJC_METTL3_EV_vs_WT_F05.03086.03086.2 0.00937 12-Jul R.MC[160.03]PATQK.L sp|Q9H307|PININ_HUMAN 1 834.3728 0.97 57910 3086 2 834.370395 418.1937 Pinin OS=Homo sapiens OX=9606 GN=PNN PE=1 SV=5 7.98 1289 - 1.39E+06 - - - -2.8764 - 1.381 0.346 - 225.6 1 2 0 -0.0024 7 0 0 0 4.55E+07 4.68E+07 - - - 2.6186 0.9759 221125_WJC_METTL3_EV_vs_WT_F05.03111.03111.2 0.503 12-Aug K.QLAEEQK[136.11].R sp|Q8TAE8|G45IP_HUMAN 1 852.4432 0.96 57922 3111 2 852.442173 427.2289 Growth arrest and DNA damage-inducible proteins-interacting protein 1 OS=Homo sapiens OX=9606 GN=GADD45GIP1 PE=1 SV=1 4.53 1292.1 - 576979 - - - -1.2599 - 1.453 0.001 - 190.8 1 2 0 -0.0011 7 0 0 0 2.55E+07 2.66E+07 - - - 0.2319 0.8013 221125_WJC_METTL3_EV_vs_WT_F05.03140.03140.2 0.905 16-Aug K.SAPATGGVK[136.11].K "sp|Q5TEC6|H3PS2_HUMAN,sp|Q16695|H31T_HUMAN,sp|Q71DI3|H32_HUMAN,sp|P68431|H31_HUMAN" 4 794.4378 1.05 57929 3140 2 794.43371 398.2262 Histone HIST2H3PS2 OS=Homo sapiens OX=9606 GN=H3-2 PE=1 SV=1 8.47 1296.4 - 1.12E+06 - - - -5.108 - 1.183 0.133 - 167.3 1 2 0 -0.0041 9 0 0 0 2.65E+08 2.53E+08 - - - 0.5083 0.9376 221125_WJC_METTL3_EV_vs_WT_F05.03144.03144.2 0.0911 16-Jul K.SAPATGGVK.K "sp|Q5TEC6|H3PS2_HUMAN,sp|Q16695|H31T_HUMAN,sp|Q71DI3|H32_HUMAN,sp|P68431|H31_HUMAN" 4 786.4236 1.06 57930 3144 2 786.419773 394.2191 Histone HIST2H3PS2 OS=Homo sapiens OX=9606 GN=H3-2 PE=1 SV=1 8.47 1297 - 1.31E+06 - - - -4.8256 - 1.36 0.183 - 159.1 1 2 0 -0.0038 9 0 0 0 2.59E+08 2.45E+08 - - - 1.281 0.9765 221125_WJC_METTL3_EV_vs_WT_F05.03163.03163.2 0.00543 14-Jun R.AMESTESR[166.11].H "sp|P55265|DSRAD_HUMAN,tr|A0A3B3IRQ9|A0A3B3IRQ9_HUMAN,tr|A0A3B3ISU1|A0A3B3ISU1_HUMAN,tr|A0A7P0Z4K3|A0A7P0Z4K3_HUMAN,tr|A0A7P0Z4F9|A0A7P0Z4F9_HUMAN" 5 919.3945 0.09 57937 3163 2 919.388282 460.7045 Double-stranded RNA-specific adenosine deaminase OS=Homo sapiens OX=9606 GN=ADAR PE=1 SV=4 4.53 1299.5 - 510396 - - - -6.7262 - 1.281 0.478 - 118.1 1 2 0 -0.0062 8 0 0 0 1.39E+07 1.50E+08 - - - 3.3164 0.9928 221125_WJC_METTL3_EV_vs_WT_F05.03172.03172.2 0.00992 14-Jul R.AMESTESR.H "sp|P55265|DSRAD_HUMAN,tr|A0A3B3IRQ9|A0A3B3IRQ9_HUMAN,tr|A0A3B3ISU1|A0A3B3ISU1_HUMAN,tr|A0A7P0Z4K3|A0A7P0Z4K3_HUMAN,tr|A0A7P0Z4F9|A0A7P0Z4F9_HUMAN" 5 909.3862 0.1 57938 3172 2 909.382263 455.7004 Double-stranded RNA-specific adenosine deaminase OS=Homo sapiens OX=9606 GN=ADAR PE=1 SV=4 4.53 1300.9 - 551352 - - - -4.3249 - 1.33 0.396 - 137.8 1 2 0 -0.0039 8 0 0 0 1.39E+07 1.39E+08 - - - 2.8247 0.9139 221125_WJC_METTL3_EV_vs_WT_F05.03199.03199.2 5.21 14-Jun K.QR[166.11]GSR[166.11]SGK[136.11].- "sp|Q13402|MYO7A_HUMAN,tr|H7C4D8|H7C4D8_HUMAN" 2 902.5041 1.19 57949 3199 2 902.503327 452.2593 Unconventional myosin-VIIa OS=Homo sapiens OX=9606 GN=MYO7A PE=1 SV=2 12.01 1304.4 - 187146 - - - -0.8033 - 1.418 0.116 - 146.6 2 2 2 -0.0007 8 0 0 0 5.39E+06 4.52E+06 - - - 0.8164 0.9507 221125_WJC_METTL3_EV_vs_WT_F05.03205.03205.2 0.135 12-Jul R.METEESR.K sp|Q9BZE4|GTPB4_HUMAN 1 880.3596 0.16 57953 3205 2 880.356651 441.1871 GTP-binding protein 4 OS=Homo sapiens OX=9606 GN=GTPBP4 PE=1 SV=3 4.25 1305 - 598972 - - - -3.4032 - 1.109 0.184 - 153.2 1 2 0 -0.003 7 0 0 0 1.21E+07 7.40E+07 - - - 0.7269 0.9863 221125_WJC_METTL3_EV_vs_WT_F05.03209.03209.2 0.0356 12-Aug K.TSNTLEK.D "sp|Q8WU79|SMAP2_HUMAN,tr|A0A087WV97|A0A087WV97_HUMAN" 2 791.4025 0.81 57955 3209 2 791.400776 396.7085 Stromal membrane-associated protein 2 OS=Homo sapiens OX=9606 GN=SMAP2 PE=1 SV=1 5.66 1305.6 - 5.04E+06 - - - -2.1759 - 1.574 0.073 - 262.9 1 2 0 -0.0017 7 0 0 0 2.77E+08 3.43E+08 - - - 1.017 0.9962 221125_WJC_METTL3_EV_vs_WT_F05.03210.03210.2 0.145 12-Aug R.LNSVNNR[166.11].A "sp|Q9NVM9|INT13_HUMAN,tr|H0YH12|H0YH12_HUMAN" 2 825.4332 3.76 57956 3210 2 825.430829 413.7239 Integrator complex subunit 13 OS=Homo sapiens OX=9606 GN=INTS13 PE=1 SV=2 9.75 1305.7 - 443330 - - - -2.9148 - 1.889 0.189 - 228.9 1 2 0 -0.0024 7 0 0 0 5.58E+07 1.48E+07 - - - 2.4516 0.9081 221125_WJC_METTL3_EV_vs_WT_F05.03213.03213.2 0.659 12-Aug K.IQAQEDR[166.11].E "sp|Q9Y3D7|TIM16_HUMAN,tr|I3L3T0|I3L3T0_HUMAN,tr|A0A0A6YYL4|A0A0A6YYL4_HUMAN,tr|I3L0X9|I3L0X9_HUMAN" 4 868.4278 0.08 57957 3213 2 868.424794 435.2212 Mitochondrial import inner membrane translocase subunit TIM16 OS=Homo sapiens OX=9606 GN=PAM16 PE=1 SV=2 4.37 1306.1 - 1.92E+06 - - - -3.4787 - 1.537 0.007 - 206.5 2 2 0 -0.003 7 0 0 0 1.33E+08 1.67E+09 - - - 0.3192 0.9983 221125_WJC_METTL3_EV_vs_WT_F05.03222.03222.2 0.00161 14-Sep R.SAAETVTK.G "sp|P61604|CH10_HUMAN,tr|S4R3N1|S4R3N1_HUMAN,tr|B8ZZL8|B8ZZL8_HUMAN" 3 805.4181 1.04 57960 3222 2 805.416096 403.7164 "10 kDa heat shock protein, mitochondrial OS=Homo sapiens OX=9606 GN=HSPE1 PE=1 SV=2" 5.72 1307.5 - 1.19E+06 - - - -2.5477 - 1.667 0.326 - 274.4 1 2 0 -0.0021 8 0 0 0 1.92E+08 1.83E+08 - - - 2.9894 0.769 221125_WJC_METTL3_EV_vs_WT_F05.03228.03228.2 1.15 12-Jun R.INEEEEK[136.11].K sp|Q8N9Q2|SR1IP_HUMAN 1 897.4171 0.71 57962 3228 2 897.413203 449.7158 Protein SREK1IP1 OS=Homo sapiens OX=9606 GN=SREK1IP1 PE=1 SV=1 4.09 1308.3 - 331688 - - - -4.3335 - 1.031 0.12 - 79.8 1 2 0 -0.0039 7 0 0 0 5.19E+06 7.34E+06 - - - 0.0228 0.9983 221125_WJC_METTL3_EV_vs_WT_F05.03233.03233.2 0.027 14-Aug K.LVQTQGTK[136.11].E "sp|P42694|HELZ_HUMAN,tr|J3QS41|J3QS41_HUMAN,tr|A0A075B6R3|A0A075B6R3_HUMAN" 3 881.5062 1.89 57966 3233 2 881.503888 441.7604 Probable helicase with zinc finger domain OS=Homo sapiens OX=9606 GN=HELZ PE=1 SV=2 8.75 1308.8 - 343139 - - - -2.6024 - 1.621 0.339 - 191.2 1 2 0 -0.0023 8 0 0 0 1.67E+08 8.84E+07 - - - 3.001 0.9849 221125_WJC_METTL3_EV_vs_WT_F05.03236.03236.2 0.308 14-Jul K.LVQTQGTK.E "sp|P42694|HELZ_HUMAN,tr|J3QS41|J3QS41_HUMAN,tr|A0A075B6R3|A0A075B6R3_HUMAN" 3 873.492 1.89 57967 3236 2 873.489247 437.7533 Probable helicase with zinc finger domain OS=Homo sapiens OX=9606 GN=HELZ PE=1 SV=2 8.75 1309.2 - 1.30E+06 - - - -3.1311 - 1.298 0.22 - 115.7 1 2 0 -0.0027 8 0 0 0 1.67E+08 8.84E+07 - - - 1.4517 0.9871 221125_WJC_METTL3_EV_vs_WT_F05.03240.03240.2 2.78 12-Jul R.LQEAENR.N "sp|P82094|TMF1_HUMAN,tr|A0A2R8Y7M0|A0A2R8Y7M0_HUMAN" 2 858.4195 0.42 57970 3240 2 858.417337 430.217 TATA element modulatory factor OS=Homo sapiens OX=9606 GN=TMF1 PE=1 SV=2 4.53 1309.6 - 1.97E+07 - - - -2.5722 - 1.652 0.086 - 181.9 1 2 0 -0.0022 7 0 0 0 3.52E+08 8.42E+08 - - - 1.2661 0.9938 221125_WJC_METTL3_EV_vs_WT_F05.03242.03242.2 0.172 14-Aug R.SAAETVTK[136.11].G "sp|P61604|CH10_HUMAN,tr|S4R3N1|S4R3N1_HUMAN,tr|B8ZZL8|B8ZZL8_HUMAN" 3 813.4323 1 57971 3242 2 813.429922 407.7235 "10 kDa heat shock protein, mitochondrial OS=Homo sapiens OX=9606 GN=HSPE1 PE=1 SV=2" 5.72 1309.8 - 7.90E+06 - - - -2.9824 - 1.579 0.225 - 219.6 1 2 0 -0.0024 8 0 0 0 1.84E+08 1.84E+08 - - - 2.0798 0.9981 221125_WJC_METTL3_EV_vs_WT_F05.03255.03255.2 0.0272 12-Jul R.FANSSDR.K "sp|O60481|ZIC3_HUMAN,sp|Q8N9L1|ZIC4_HUMAN,sp|Q96T25|ZIC5_HUMAN,sp|O95409|ZIC2_HUMAN,sp|Q15915|ZIC1_HUMAN,tr|H7C5D8|H7C5D8_HUMAN" 6 795.3511 2.04 57977 3255 2 795.349284 398.6828 Zinc finger protein ZIC 3 OS=Homo sapiens OX=9606 GN=ZIC3 PE=1 SV=1 5.84 1311.6 - 3.65E+06 - - - -2.3222 - 1.43 0.339 - 132.4 1 2 0 -0.0018 7 0 0 0 3.85E+08 1.89E+08 - - - 2.6776 0.9789 221125_WJC_METTL3_EV_vs_WT_F05.03264.03264.2 0.111 12-Jul R.TTLSQTK.Q "sp|O43795|MYO1B_HUMAN,tr|E9PDF6|E9PDF6_HUMAN,tr|H7C2Y7|H7C2Y7_HUMAN" 3 777.4232 6.72 57980 3264 2 777.421015 389.7189 Unconventional myosin-Ib OS=Homo sapiens OX=9606 GN=MYO1B PE=1 SV=3 8.41 1312.8 - 761575 - - - -2.853 - 1.461 0.11 - 316 1 2 0 -0.0022 7 0 0 0 1.99E+08 2.97E+07 - - - 1.054 0.9984 221125_WJC_METTL3_EV_vs_WT_F05.03268.03268.2 0.0138 12-Jul R.FANSSDR[166.11].K "sp|O60481|ZIC3_HUMAN,sp|Q8N9L1|ZIC4_HUMAN,sp|Q96T25|ZIC5_HUMAN,sp|O95409|ZIC2_HUMAN,sp|Q15915|ZIC1_HUMAN,tr|H7C5D8|H7C5D8_HUMAN" 6 805.3594 2.04 57982 3268 2 805.357682 403.687 Zinc finger protein ZIC 3 OS=Homo sapiens OX=9606 GN=ZIC3 PE=1 SV=1 5.84 1313.3 - 5.76E+06 - - - -2.1345 - 1.408 0.353 - 136 1 2 0 -0.0017 7 0 0 0 3.85E+08 1.88E+08 - - - 2.7319 0.9985 221125_WJC_METTL3_EV_vs_WT_F05.03269.03269.2 0.0206 14-Sep R.VGNTPETR[166.11].G sp|Q9Y3B4|SF3B6_HUMAN 1 882.4435 1.31 57983 3269 2 882.44321 442.229 Splicing factor 3B subunit 6 OS=Homo sapiens OX=9606 GN=SF3B6 PE=1 SV=1 5.97 1313.3 - 3.51E+06 - - - -0.289 - 1.582 0.213 - 206.6 1 2 0 -0.0003 8 0 0 0 9.95E+08 7.62E+08 - - - 1.9975 0.9977 221125_WJC_METTL3_EV_vs_WT_F05.03278.03278.2 0.0511 14-Jul R.LTEEGQEK[136.11].G "sp|Q9H0G5|NSRP1_HUMAN,tr|A0A024QZ33|A0A024QZ33_HUMAN" 2 940.4593 1.38 57987 3278 2 940.458354 471.2369 Nuclear speckle splicing regulatory protein 1 OS=Homo sapiens OX=9606 GN=NSRP1 PE=1 SV=1 4.25 1314.6 - 431187 - - - -0.9963 - 1.299 0.271 - 141.6 1 2 0 -0.0009 8 0 0 0 1.11E+07 8.05E+06 - - - 1.8313 0.8579 221125_WJC_METTL3_EV_vs_WT_F05.03288.03288.2 0.0713 12-Jun K.AYEDGC[160.03]K[136.11].T "sp|P31948|STIP1_HUMAN,tr|F5GXD8|F5GXD8_HUMAN,tr|F5H783|F5H783_HUMAN" 3 849.3418 0.48 57991 3288 2 849.338677 425.6782 Stress-induced-phosphoprotein 1 OS=Homo sapiens OX=9606 GN=STIP1 PE=1 SV=1 4.37 1315.9 - 656253 - - - -3.6993 - 1.159 0.081 - 111.5 1 2 0 -0.0031 7 0 0 0 3.02E+07 6.33E+07 - - - 0.1058 0.9795 221125_WJC_METTL3_EV_vs_WT_F05.03292.03292.2 0.5 12-Jun R.NVADDTR.S "sp|O75494|SRS10_HUMAN,tr|Q5JRI1|Q5JRI1_HUMAN,tr|Q6IQ42|Q6IQ42_HUMAN" 3 789.3617 1.75 57993 3292 2 789.35881 395.6881 Serine\arginine-rich splicing factor 10 OS=Homo sapiens OX=9606 GN=SRSF10 PE=1 SV=1 4.21 1316.3 - 1.43E+07 - - - -3.6561 - 1.299 0.222 - 189.7 1 2 0 -0.0029 7 0 0 0 4.51E+08 2.58E+08 - - - 1.5087 0.9955 221125_WJC_METTL3_EV_vs_WT_F05.03293.03293.2 7.98 12-Jul R.AIDQEEK[136.11].G "sp|Q8NF37|PCAT1_HUMAN,tr|A0A0G2JQ62|A0A0G2JQ62_HUMAN,tr|A0A0G2JRI7|A0A0G2JRI7_HUMAN" 3 839.4116 1.91 57994 3293 2 839.410459 420.7131 Lysophosphatidylcholine acyltransferase 1 OS=Homo sapiens OX=9606 GN=LPCAT1 PE=1 SV=2 4.14 1316.4 - 643704 - - - -1.3736 - 1.272 0.223 - 183.3 1 2 0 -0.0012 7 0 0 0 2.54E+07 1.33E+07 - - - 1.45 0.97 221125_WJC_METTL3_EV_vs_WT_F05.03298.03298.2 0.183 12-Jul K.LTPQGQR[166.11].D "sp|P39019|RS19_HUMAN,tr|A0A075B6E2|A0A075B6E2_HUMAN" 2 808.4431 1.08 57997 3298 2 808.440335 405.2288 40S ribosomal protein S19 OS=Homo sapiens OX=9606 GN=RPS19 PE=1 SV=2 9.75 1316.9 - 3.24E+07 - - - -3.3843 - 1.163 0.211 - 208.4 1 2 0 -0.0027 7 0 0 0 6.76E+09 6.26E+09 - - - 1.077 0.9975 221125_WJC_METTL3_EV_vs_WT_F05.03303.03303.2 0.499 14-Nov R.HLAGEVAK[136.11].E sp|Q13200|PSMD2_HUMAN 1 831.4694 0.86 58000 3303 2 831.465802 416.742 26S proteasome non-ATPase regulatory subunit 2 OS=Homo sapiens OX=9606 GN=PSMD2 PE=1 SV=3 6.75 1317.4 - 2.04E+06 - - - -4.3297 - 2.087 0.374 - 491.3 1 2 0 -0.0036 8 0 0 0 3.48E+07 4.06E+07 - - - 4.0212 0.9786 221125_WJC_METTL3_EV_vs_WT_F05.03313.03313.2 0.00041 14-Aug R.AGQDDEVR[166.11].L "sp|Q06547|GABP1_HUMAN,tr|H9ZYI9|H9ZYI9_HUMAN,tr|H0YNZ0|H0YNZ0_HUMAN" 3 898.402 2.98 58003 3313 2 898.395524 450.2083 GA-binding protein subunit beta-1 OS=Homo sapiens OX=9606 GN=GABPB1 PE=1 SV=2 4.03 1318.9 - 1.09E+06 - - - -7.2017 - 1.668 0.432 - 351.6 1 2 0 -0.0065 8 0 0 0 6.19E+07 2.07E+07 - - - 3.7728 0.9942 221125_WJC_METTL3_EV_vs_WT_F05.03314.03314.2 0.00767 14-Aug R.LATC[160.03]SSDR.S "sp|P55735|SEC13_HUMAN,tr|A8MXL6|A8MXL6_HUMAN,tr|E7ERC8|E7ERC8_HUMAN" 3 908.4022 1.48 58004 3314 2 908.398748 455.2084 Protein SEC13 homolog OS=Homo sapiens OX=9606 GN=SEC13 PE=1 SV=3 5.83 1319 - 2.83E+06 - - - -3.7792 - 1.688 0.275 - 225 1 2 0 -0.0034 8 0 0 0 4.18E+07 2.82E+07 - - - 2.6501 0.9947 221125_WJC_METTL3_EV_vs_WT_F05.03315.03315.2 0.34 14-Jul K.EAAQEAVK.L "sp|O60506|HNRPQ_HUMAN,sp|O43390|HNRPR_HUMAN,tr|B4DT28|B4DT28_HUMAN,tr|A0A7I2YQN2|A0A7I2YQN2_HUMAN,tr|A0A7I2V5Q6|A0A7I2V5Q6_HUMAN,tr|A0A7I2V4Z0|A0A7I2V4Z0_HUMAN,tr|B7Z645|B7Z645_HUMAN,tr|A0A6Q8PH31|A0A6Q8PH31_HUMAN,tr|A0A6Q8PEX7|A0A6Q8PEX7_HUMAN,tr|A0A7I2V2F2|A0A7I2V2F2_HUMAN,tr|A0A7I2V346|A0A7I2V346_HUMAN,tr|A0A7I2V309|A0A7I2V309_HUMAN,tr|A0A6Q8PH35|A0A6Q8PH35_HUMAN" 13 844.429 1.15 58005 3315 2 844.428001 423.2218 Heterogeneous nuclear ribonucleoprotein Q OS=Homo sapiens OX=9606 GN=SYNCRIP PE=1 SV=2 4.53 1319 - 1.39E+06 - - - -1.2387 - 1.478 0.143 - 207.1 1 2 0 -0.001 8 0 0 0 5.33E+08 4.62E+08 - - - 1.2752 0.9961 221125_WJC_METTL3_EV_vs_WT_F05.03318.03318.2 0.0192 14-Jun R.AGQDDEVR.L "sp|Q06547|GABP1_HUMAN,tr|H9ZYI9|H9ZYI9_HUMAN,tr|H0YNZ0|H0YNZ0_HUMAN" 3 888.3937 2.99 58006 3318 2 888.390474 445.2041 GA-binding protein subunit beta-1 OS=Homo sapiens OX=9606 GN=GABPB1 PE=1 SV=2 4.03 1319.4 - 3.34E+06 - - - -3.6583 - 1.558 0.348 - 217.3 1 2 0 -0.0032 8 0 0 0 6.18E+07 2.07E+07 - - - 2.9476 0.9816 221125_WJC_METTL3_EV_vs_WT_F05.03320.03320.2 0.0668 14-Oct R.TPQSVTAK.Q "sp|Q86UE4|LYRIC_HUMAN,tr|H0YB56|H0YB56_HUMAN,tr|E5RJU9|E5RJU9_HUMAN" 3 830.4498 0.4 58007 3320 2 830.446017 416.2322 Protein LYRIC OS=Homo sapiens OX=9606 GN=MTDH PE=1 SV=2 8.41 1319.6 - 4.54E+06 - - - -4.5337 - 1.642 0.213 - 394.6 1 2 0 -0.0038 8 0 0 0 9.63E+07 2.39E+08 - - - 2.1087 0.996 221125_WJC_METTL3_EV_vs_WT_F05.03333.03333.2 0.126 14-Aug K.TSATVGPK.A sp|P16104|H2AX_HUMAN 1 759.4127 6.39 58014 3333 2 759.410254 380.7136 Histone H2AX OS=Homo sapiens OX=9606 GN=H2AX PE=1 SV=2 8.41 1321 - 2.26E+06 - - - -3.1801 - 1.714 0.261 - 287.8 1 2 0 -0.0024 8 0 0 0 4.04E+08 6.33E+07 - - - 2.5931 0.9929 221125_WJC_METTL3_EV_vs_WT_F05.03344.03344.2 0.0204 14-Aug K.EAAQEAVK[136.11].L "sp|O60506|HNRPQ_HUMAN,sp|O43390|HNRPR_HUMAN,tr|B4DT28|B4DT28_HUMAN,tr|A0A7I2YQN2|A0A7I2YQN2_HUMAN,tr|A0A7I2V5Q6|A0A7I2V5Q6_HUMAN,tr|A0A7I2V4Z0|A0A7I2V4Z0_HUMAN,tr|B7Z645|B7Z645_HUMAN,tr|A0A6Q8PH31|A0A6Q8PH31_HUMAN,tr|A0A6Q8PEX7|A0A6Q8PEX7_HUMAN,tr|A0A7I2V2F2|A0A7I2V2F2_HUMAN,tr|A0A7I2V346|A0A7I2V346_HUMAN,tr|A0A7I2V309|A0A7I2V309_HUMAN,tr|A0A6Q8PH35|A0A6Q8PH35_HUMAN" 13 852.4432 1.12 58020 3344 2 852.439691 427.2289 Heterogeneous nuclear ribonucleoprotein Q OS=Homo sapiens OX=9606 GN=SYNCRIP PE=1 SV=2 4.53 1322.3 - 2.06E+07 - - - -4.1715 - 1.672 0.29 - 347.3 1 2 0 -0.0036 8 0 0 0 5.35E+08 4.77E+08 - - - 2.7321 0.9965 221125_WJC_METTL3_EV_vs_WT_F05.03353.03353.2 0.198 18-Nov K.TAEAGGVTGK[136.11].G "sp|P09874|PARP1_HUMAN,tr|A0A7I2V5E9|A0A7I2V5E9_HUMAN,tr|A0A7I2V625|A0A7I2V625_HUMAN,tr|A0A7I2V3E1|A0A7I2V3E1_HUMAN" 4 897.4647 1.12 58026 3353 2 897.462051 449.7396 Poly [ADP-ribose] polymerase 1 OS=Homo sapiens OX=9606 GN=PARP1 PE=1 SV=4 5.66 1323.4 - 571755 - - - -2.9639 - 1.955 0.224 - 443.1 1 2 0 -0.0027 10 0 0 0 2.67E+07 2.38E+07 - - - 2.5659 0.9989 221125_WJC_METTL3_EV_vs_WT_F05.03368.03368.2 0.00709 18-Sep R.EAAEAGAEAR[166.11].L "sp|Q14160|SCRIB_HUMAN,tr|A0A669KB89|A0A669KB89_HUMAN,tr|A0A0G2JPP5|A0A0G2JPP5_HUMAN,tr|A0A0G2JNZ2|A0A0G2JNZ2_HUMAN,tr|A0A0G2JMS7|A0A0G2JMS7_HUMAN,tr|H0YCG0|H0YCG0_HUMAN" 6 983.4548 1.99 58033 3368 2 983.451284 492.7347 Protein scribble homolog OS=Homo sapiens OX=9606 GN=SCRIB PE=1 SV=4 4.25 1325.2 - 280243 - - - -3.5324 - 1.964 0.466 - 268.3 1 2 0 -0.0035 10 0 0 0 1.06E+07 5.32E+06 - - - 4.3659 0.9804 221125_WJC_METTL3_EV_vs_WT_F05.03371.03371.2 0.0918 14-Jul K.TLAEQNTK.N sp|Q14966|ZN638_HUMAN 1 903.4662 0.57 58035 3371 2 903.462375 452.7404 Zinc finger protein 638 OS=Homo sapiens OX=9606 GN=ZNF638 PE=1 SV=2 5.66 1325.6 - 562490 - - - -4.1905 - 1.346 0.277 - 105.6 2 2 0 -0.0038 8 0 0 0 1.54E+07 2.70E+07 - - - 1.8474 0.9933 221125_WJC_METTL3_EV_vs_WT_F05.03372.03372.2 0.119 14-Aug K.TLAEQNTK[136.11].N sp|Q14966|ZN638_HUMAN 1 911.4804 0.57 58036 3372 2 911.477619 456.7475 Zinc finger protein 638 OS=Homo sapiens OX=9606 GN=ZNF638 PE=1 SV=2 5.66 1325.7 - 859803 - - - -3.0083 - 1.404 0.265 - 99.8 1 2 0 -0.0027 8 0 0 0 1.54E+07 2.70E+07 - - - 2.0208 0.9927 221125_WJC_METTL3_EV_vs_WT_F05.03373.03373.2 0.0506 18-Oct R.EAAEAGAEAR.L "sp|Q14160|SCRIB_HUMAN,tr|A0A669KB89|A0A669KB89_HUMAN,tr|A0A0G2JPP5|A0A0G2JPP5_HUMAN,tr|A0A0G2JNZ2|A0A0G2JNZ2_HUMAN,tr|A0A0G2JMS7|A0A0G2JMS7_HUMAN,tr|H0YCG0|H0YCG0_HUMAN" 6 973.4465 2.02 58037 3373 2 973.441971 487.7305 Protein scribble homolog OS=Homo sapiens OX=9606 GN=SCRIB PE=1 SV=4 4.25 1325.8 - 312162 - - - -4.6402 - 1.749 0.329 - 195.6 1 2 0 -0.0045 10 0 0 0 1.08E+07 5.32E+06 - - - 3.03 0.971 221125_WJC_METTL3_EV_vs_WT_F05.03384.03384.2 0.307 12-Jul K.TQLSQGR.S sp|Q8ND56|LS14A_HUMAN 1 788.4141 0.1 58042 3384 2 788.410748 395.2143 Protein LSM14 homolog A OS=Homo sapiens OX=9606 GN=LSM14A PE=1 SV=3 9.41 1327.1 - 3.27E+07 - - - -4.2084 - 1.336 0.215 - 284.4 1 2 0 -0.0033 7 0 0 0 6.33E+08 6.55E+09 - - - 1.5458 0.9977 221125_WJC_METTL3_EV_vs_WT_F05.03390.03390.2 0.000279 14-Aug K.VMTDESGK.S "sp|Q9H361|PABP3_HUMAN,sp|P11940|PABP1_HUMAN,tr|A0A7I2YQE4|A0A7I2YQE4_HUMAN,tr|A0A7I2V649|A0A7I2V649_HUMAN,tr|H0YAR2|H0YAR2_HUMAN,tr|E7ERJ7|E7ERJ7_HUMAN,tr|A0A7I2YQ88|A0A7I2YQ88_HUMAN,tr|A0A087WTT1|A0A087WTT1_HUMAN,tr|H0YAP2|H0YAP2_HUMAN,tr|A0A7I2YQ90|A0A7I2YQ90_HUMAN,tr|A0A7I2V4N4|A0A7I2V4N4_HUMAN,tr|E7EQV3|E7EQV3_HUMAN" 12 865.3851 1.16 58044 3390 2 865.381275 433.6998 Polyadenylate-binding protein 3 OS=Homo sapiens OX=9606 GN=PABPC3 PE=1 SV=2 4.37 1327.9 - 1.96E+06 - - - -4.4581 - 1.554 0.522 - 238.6 1 2 0 -0.0039 8 0 0 0 2.83E+08 2.44E+08 - - - 4.2248 0.9962 221125_WJC_METTL3_EV_vs_WT_F05.03393.03393.2 0.00943 16-Sep R.AAVAGEDGR.M "sp|P0DMR1|HNRC4_HUMAN,sp|P07910|HNRPC_HUMAN,sp|O60812|HNRC1_HUMAN,sp|B2RXH8|HNRC2_HUMAN,sp|B7ZW38|HNRC3_HUMAN,tr|G3V251|G3V251_HUMAN,tr|B4DY08|B4DY08_HUMAN,tr|G3V575|G3V575_HUMAN,tr|B4DSU6|B4DSU6_HUMAN,tr|G3V3K6|G3V3K6_HUMAN,tr|B2R5W2|B2R5W2_HUMAN,tr|G3V4C1|G3V4C1_HUMAN,tr|A0A0G2JPF8|A0A0G2JPF8_HUMAN,tr|A0A0G2JNQ3|A0A0G2JNQ3_HUMAN,tr|G3V576|G3V576_HUMAN,tr|G3V5X6|G3V5X6_HUMAN,tr|G3V4W0|G3V4W0_HUMAN,tr|G3V555|G3V555_HUMAN,tr|G3V2Q1|G3V2Q1_HUMAN" 19 844.4039 1.7 58045 3393 2 844.399763 423.2092 Heterogeneous nuclear ribonucleoprotein C-like 4 OS=Homo sapiens OX=9606 GN=HNRNPCL4 PE=3 SV=1 4.37 1328.3 - 3.82E+07 - - - -4.8934 - 2.085 0.382 - 327.8 1 2 0 -0.0041 9 0 0 0 6.74E+09 3.97E+09 - - - 3.9869 0.9936 221125_WJC_METTL3_EV_vs_WT_F05.03443.03443.2 0.00169 14-Sep R.LVSNESQR.R "sp|Q5JPH6|SYEM_HUMAN,tr|H3BTB7|H3BTB7_HUMAN" 2 931.4723 1.65 58055 3443 2 931.468377 466.7434 "Probable glutamate--tRNA ligase, mitochondrial OS=Homo sapiens OX=9606 GN=EARS2 PE=1 SV=2" 6 1335.7 - 5.09E+06 - - - -4.2213 - 1.774 0.283 - 299.3 1 2 0 -0.0039 8 0 0 0 7.05E+07 4.27E+07 - - - 2.8589 0.9465 221125_WJC_METTL3_EV_vs_WT_F05.03446.03446.2 0.297 12-Jul K.LSPANQR[166.11].K "sp|Q13263|TIF1B_HUMAN,tr|M0R0K9|M0R0K9_HUMAN" 2 794.4274 0.76 58056 3446 2 794.424204 398.221 Transcription intermediary factor 1-beta OS=Homo sapiens OX=9606 GN=TRIM28 PE=1 SV=5 9.75 1336 - 5.01E+06 - - - -4.0495 - 1.482 0.114 - 286 2 2 0 -0.0032 7 0 0 0 1.68E+08 2.21E+08 - - - 0.994 0.9912 221125_WJC_METTL3_EV_vs_WT_F05.03450.03450.2 0.0101 14-Jul R.IVENGQER[166.11].V "sp|Q8NHS0|DNJB8_HUMAN,sp|O75190|DNJB6_HUMAN,tr|A0A0J9YX62|A0A0J9YX62_HUMAN,tr|C9J2C4|C9J2C4_HUMAN" 4 953.4806 1.42 58057 3450 2 953.475708 477.7476 DnaJ homolog subfamily B member 8 OS=Homo sapiens OX=9606 GN=DNAJB8 PE=1 SV=1 4.53 1336.6 - 5.83E+06 - - - -5.1087 - 1.476 0.403 - 159 1 2 0 -0.0049 8 0 0 0 4.59E+08 3.24E+08 - - - 3.1902 0.9941 221125_WJC_METTL3_EV_vs_WT_F05.03452.03452.2 0.000648 14-Jul R.IVENGQER.V "sp|Q8NHS0|DNJB8_HUMAN,sp|O75190|DNJB6_HUMAN,tr|A0A0J9YX62|A0A0J9YX62_HUMAN,tr|C9J2C4|C9J2C4_HUMAN" 4 943.4723 1.42 58058 3452 2 943.46782 472.7434 DnaJ homolog subfamily B member 8 OS=Homo sapiens OX=9606 GN=DNAJB8 PE=1 SV=1 4.53 1336.8 - 9.05E+06 - - - -4.758 - 1.486 0.423 - 159 1 2 0 -0.0045 8 0 0 0 4.59E+08 3.24E+08 - - - 3.3585 0.9277 221125_WJC_METTL3_EV_vs_WT_F05.03454.03454.2 0.042 12-Jul R.MVQEAEK.Y "sp|P0DMV8|HS71A_HUMAN,sp|P11142|HSP7C_HUMAN,sp|P0DMV9|HS71B_HUMAN,tr|E9PNE6|E9PNE6_HUMAN,tr|A8K7Q2|A8K7Q2_HUMAN,tr|E9PKE3|E9PKE3_HUMAN,tr|E9PM13|E9PM13_HUMAN,tr|E9PS65|E9PS65_HUMAN,tr|V9GZ37|V9GZ37_HUMAN,tr|A0A0G2JIW1|A0A0G2JIW1_HUMAN" 10 833.3953 0.11 58060 3454 2 833.38958 417.7049 Heat shock 70 kDa protein 1A OS=Homo sapiens OX=9606 GN=HSPA1A PE=1 SV=1 4.53 1337.1 - 3.42E+06 - - - -6.8683 - 1.345 0.311 - 171.6 1 2 0 -0.0057 7 0 0 0 7.58E+07 6.75E+08 - - - 2.2754 0.9859 221125_WJC_METTL3_EV_vs_WT_F05.03461.03461.2 0.0112 14-Aug K.LNTAEDAK[136.11].D "sp|P46060|RAGP1_HUMAN,tr|B0QYT4|B0QYT4_HUMAN,tr|B0QYT5|B0QYT5_HUMAN" 3 868.4382 1.11 58062 3461 2 868.433314 435.2264 Ran GTPase-activating protein 1 OS=Homo sapiens OX=9606 GN=RANGAP1 PE=1 SV=1 4.37 1338 - 3.48E+06 - - - -5.5824 - 1.801 0.301 - 192.5 1 2 0 -0.0048 8 0 0 0 1.08E+08 9.68E+07 - - - 3.0371 0.9868 221125_WJC_METTL3_EV_vs_WT_F05.03466.03466.2 0.765 12-Jun K.FQGENTK[136.11].S "sp|Q96CT7|CC124_HUMAN,tr|M0R2F5|M0R2F5_HUMAN" 2 830.4014 2.53 58064 3466 2 830.398783 416.208 Coiled-coil domain-containing protein 124 OS=Homo sapiens OX=9606 GN=CCDC124 PE=1 SV=1 6 1338.7 - 1.32E+06 - - - -3.1298 - 1.239 0.249 - 90.7 1 2 0 -0.0026 7 0 0 0 1.13E+08 4.46E+07 - - - 1.5583 0.9547 221125_WJC_METTL3_EV_vs_WT_F05.03475.03475.2 0.131 14-Jun K.IVTDSNSR.V sp|Q68EM7|RHG17_HUMAN 1 890.4458 1.35 58069 3475 2 890.4422 446.2302 Rho GTPase-activating protein 17 OS=Homo sapiens OX=9606 GN=ARHGAP17 PE=1 SV=1 5.84 1339.6 - 2.99E+06 - - - -3.998 - 1.237 0.191 - 115.5 1 2 0 -0.0036 8 0 0 0 1.05E+08 7.76E+07 - - - 1.0921 0.8156 221125_WJC_METTL3_EV_vs_WT_F05.03483.03483.2 0.603 18-Jul K.LGSQAGEAAK.V sp|Q14469|HES1_HUMAN 1 930.4771 3.89 58073 3483 2 930.475251 466.2458 Transcription factor HES-1 OS=Homo sapiens OX=9606 GN=HES1 PE=1 SV=1 6 1340.6 - 742567 - - - -1.9442 - 1.02 0.021 - 63.7 2 2 0 -0.0018 10 0 0 0 1.36E+07 3.50E+06 - - - -0.8837 0.9924 221125_WJC_METTL3_EV_vs_WT_F05.03486.03486.2 1.18 12-Jul R.IC[160.03]SEEER[166.11].A "sp|Q9NX63|MIC19_HUMAN,tr|A0A286YEX5|A0A286YEX5_HUMAN,tr|F8WAR4|F8WAR4_HUMAN,tr|C9JRZ6|C9JRZ6_HUMAN" 4 931.3945 2.02 58074 3486 2 931.392601 466.7045 MICOS complex subunit MIC19 OS=Homo sapiens OX=9606 GN=CHCHD3 PE=1 SV=1 4.25 1341 - 720785 - - - -2.0024 - 1.373 0.177 - 133.9 1 2 0 -0.0019 7 0 0 0 1.72E+08 8.49E+07 - - - 1.3522 0.9883 221125_WJC_METTL3_EV_vs_WT_F05.03489.03489.2 1.99 12-Jul R.IC[160.03]SEEER.A "sp|Q9NX63|MIC19_HUMAN,tr|A0A286YEX5|A0A286YEX5_HUMAN,tr|F8WAR4|F8WAR4_HUMAN,tr|C9JRZ6|C9JRZ6_HUMAN" 4 921.3862 2.02 58075 3489 2 921.383479 461.7004 MICOS complex subunit MIC19 OS=Homo sapiens OX=9606 GN=CHCHD3 PE=1 SV=1 4.25 1341.4 - 973931 - - - -2.9488 - 1.51 0.163 - 159.4 1 2 0 -0.0027 7 0 0 0 1.72E+08 8.49E+07 - - - 1.5499 0.9978 221125_WJC_METTL3_EV_vs_WT_F05.03502.03502.2 0.147 14-Nov R.LAQATQER[166.11].T sp|Q9UQE7|SMC3_HUMAN 1 925.4857 0.82 58081 3502 2 925.483348 463.7501 Structural maintenance of chromosomes protein 3 OS=Homo sapiens OX=9606 GN=SMC3 PE=1 SV=2 6 1343.1 - 1.20E+06 - - - -2.5025 - 1.943 0.221 - 489.8 1 2 0 -0.0023 8 0 0 0 1.51E+08 1.84E+08 - - - 2.6759 0.9909 221125_WJC_METTL3_EV_vs_WT_F05.03503.03503.2 0.4 14-Jun R.LAQATQER.T sp|Q9UQE7|SMC3_HUMAN 1 915.4774 0.82 58082 3503 2 915.474382 458.746 Structural maintenance of chromosomes protein 3 OS=Homo sapiens OX=9606 GN=SMC3 PE=1 SV=2 6 1343.2 - 647780 - - - -3.2901 - 1.457 0.239 - 135.2 1 2 0 -0.003 8 0 0 0 1.51E+08 1.84E+08 - - - 1.9405 0.77 221125_WJC_METTL3_EV_vs_WT_F05.03506.03506.2 0.123 14-Jun K.AEQELGFA.L sp|Q03167|TGBR3_HUMAN 1 863.4025 - 58083 3506 2 863.403212 432.7085 Transforming growth factor beta receptor type 3 OS=Homo sapiens OX=9606 GN=TGFBR3 PE=1 SV=3 3.8 1343.6 - 1.70E+06 - - - 0.827 - 1.071 0.272 - 123.5 1 1 0 0.0007 8 0 0 0 - - - - - 1.2566 0.9961 221125_WJC_METTL3_EV_vs_WT_F05.03507.03507.2 5.27E-05 14-Sep K.MVSGC[160.03]QTR.S sp|Q8N1G4|LRC47_HUMAN 1 937.411 0.76 58084 3507 2 937.40625 469.7128 Leucine-rich repeat-containing protein 47 OS=Homo sapiens OX=9606 GN=LRRC47 PE=1 SV=1 8 1343.7 - 663287 - - - -5.0362 - 1.596 0.493 - 249.5 1 2 0 -0.0047 8 0 0 0 1.92E+07 2.53E+07 - - - 4.0908 0.9947 221125_WJC_METTL3_EV_vs_WT_F05.03508.03508.2 0.0108 12-Jun K.MDPNTGR[166.11].S "sp|Q99729|ROAA_HUMAN,tr|D6R9P3|D6R9P3_HUMAN,tr|D6RD18|D6RD18_HUMAN,tr|D6RBZ0|D6RBZ0_HUMAN" 4 799.3522 4.42 58085 3508 2 799.349671 400.6834 Heterogeneous nuclear ribonucleoprotein A\B OS=Homo sapiens OX=9606 GN=HNRNPAB PE=1 SV=2 5.59 1343.8 - 1.48E+06 - - - -3.1726 - 1.284 0.337 - 227.1 1 2 0 -0.0025 7 0 0 0 6.13E+08 1.39E+08 - - - 2.3214 0.9855 221125_WJC_METTL3_EV_vs_WT_F05.03513.03513.2 0.8 12-Jul K.QSEGLTK.E "sp|P51572|BAP31_HUMAN,tr|A0A2R8Y5M6|A0A2R8Y5M6_HUMAN" 2 761.3919 0 58088 3513 2 761.389758 381.7032 B-cell receptor-associated protein 31 OS=Homo sapiens OX=9606 GN=BCAP31 PE=1 SV=3 6 1344.4 - 5.66E+06 - - - -2.8566 - 1.43 0.157 - 250.5 1 2 0 -0.0022 7 0 0 0 1.62E+08 5.77E+10 - - - 1.3332 0.9851 221125_WJC_METTL3_EV_vs_WT_F05.03514.03514.2 0.115 16-Aug R.GAVQSGVDK[136.11].T "sp|O60664|PLIN3_HUMAN,tr|K7ERZ3|K7ERZ3_HUMAN,tr|K7EL96|K7EL96_HUMAN" 3 867.4541 1.03 58089 3514 2 867.45108 434.7343 Perilipin-3 OS=Homo sapiens OX=9606 GN=PLIN3 PE=1 SV=3 5.84 1344.5 - 1.61E+06 - - - -3.5345 - 1.706 0.15 - 201.3 1 2 0 -0.0031 9 0 0 0 4.35E+07 4.24E+07 - - - 1.6933 0.9998 221125_WJC_METTL3_EV_vs_WT_F05.03515.03515.2 3.96E-06 14-Oct K.MVSGC[160.03]QTR[166.11].S sp|Q8N1G4|LRC47_HUMAN 1 947.4192 0.76 58090 3515 2 947.41779 474.7169 Leucine-rich repeat-containing protein 47 OS=Homo sapiens OX=9606 GN=LRRC47 PE=1 SV=1 8 1344.6 - 999555 - - - -1.5315 - 1.76 0.52 - 318.9 1 2 0 -0.0015 8 0 0 0 1.92E+07 2.53E+07 - - - 4.5862 0.9922 221125_WJC_METTL3_EV_vs_WT_F05.03524.03524.2 0.00134 16-Sep K.ITGC[160.03]ASPGK[136.11].T sp|P50991|TCPD_HUMAN 1 897.447 0.42 58093 3524 2 897.44111 449.7308 T-complex protein 1 subunit delta OS=Homo sapiens OX=9606 GN=CCT4 PE=1 SV=4 8.22 1345.9 - 2.10E+06 - - - -6.5096 - 1.778 0.524 - 247.5 1 2 0 -0.0058 9 0 0 0 2.09E+08 4.95E+08 - - - 4.5744 0.9974 221125_WJC_METTL3_EV_vs_WT_F05.03533.03533.2 0.0112 12-Jul R.IQNGSYK.S "sp|Q86U86|PB1_HUMAN,tr|H0Y5B5|H0Y5B5_HUMAN,tr|E7EVG2|E7EVG2_HUMAN" 3 808.4079 1.18 58097 3533 2 808.406541 405.2112 Protein polybromo-1 OS=Homo sapiens OX=9606 GN=PBRM1 PE=1 SV=1 8.59 1347 - 1.86E+06 - - - -1.7033 - 1.642 0.21 - 114.1 2 2 0 -0.0014 7 0 0 0 1.00E+08 8.50E+07 - - - 2.0285 0.9978 221125_WJC_METTL3_EV_vs_WT_F05.03543.03543.2 0.00942 16-Aug K.ITGC[160.03]ASPGK.T sp|P50991|TCPD_HUMAN 1 889.4328 0.44 58100 3543 2 889.430234 445.7237 T-complex protein 1 subunit delta OS=Homo sapiens OX=9606 GN=CCT4 PE=1 SV=4 8.22 1348.3 - 2.08E+06 - - - -2.831 - 1.485 0.369 - 162.4 1 2 0 -0.0025 9 0 0 0 2.19E+08 4.95E+08 - - - 2.9096 0.9969 221125_WJC_METTL3_EV_vs_WT_F05.03547.03547.2 0.0937 12-Jun K.MDPNTGR.S "sp|Q99729|ROAA_HUMAN,tr|D6R9P3|D6R9P3_HUMAN,tr|D6RD18|D6RD18_HUMAN,tr|D6RBZ0|D6RBZ0_HUMAN" 4 789.3439 4.42 58102 3547 2 789.342818 395.6792 Heterogeneous nuclear ribonucleoprotein A\B OS=Homo sapiens OX=9606 GN=HNRNPAB PE=1 SV=2 5.59 1348.8 - 5.11E+06 - - - -1.4176 - 1.079 0.335 - 187.5 1 2 0 -0.0011 7 0 0 0 6.13E+08 1.39E+08 - - - 1.7559 0.9996 221125_WJC_METTL3_EV_vs_WT_F05.03551.03551.2 0.00909 16-Nov K.QGVAEAAGK[136.11].T "sp|P37840|SYUA_HUMAN,tr|A0A669KB41|A0A669KB41_HUMAN,tr|D6RA31|D6RA31_HUMAN,tr|A0A669KBH5|A0A669KBH5_HUMAN,tr|H6UYS7|H6UYS7_HUMAN,tr|E7EPV7|E7EPV7_HUMAN" 6 837.4436 1.59 58103 3551 2 837.441826 419.7291 Alpha-synuclein OS=Homo sapiens OX=9606 GN=SNCA PE=1 SV=1 6 1349.3 - 2.20E+06 - - - -2.0957 - 1.888 0.461 - 461.4 1 2 0 -0.0018 9 0 0 0 3.49E+09 2.19E+09 - - - 4.284 0.9988 221125_WJC_METTL3_EV_vs_WT_F05.03554.03554.2 0.0216 14-Jun R.VANC[160.03]QTVR[166.11].M "sp|Q9Y4A5|TRRAP_HUMAN,tr|H0Y4W2|H0Y4W2_HUMAN,tr|F2Z2U4|F2Z2U4_HUMAN" 3 956.4737 0.86 58104 3554 2 956.472867 479.2441 Transformation\transcription domain-associated protein OS=Homo sapiens OX=9606 GN=TRRAP PE=1 SV=3 8.22 1349.7 - 240444 - - - -0.8908 - 1.448 0.292 - 116.8 1 2 0 -0.0009 8 0 0 0 1.79E+07 2.09E+07 - - - 2.3139 0.8183 221125_WJC_METTL3_EV_vs_WT_F05.03558.03558.2 3.81 14-May R.AAPAVQTK.T "sp|P55084|ECHB_HUMAN,tr|C9K0M0|C9K0M0_HUMAN,tr|C9JE81|C9JE81_HUMAN,tr|F5GZQ3|F5GZQ3_HUMAN,tr|B5MD38|B5MD38_HUMAN,tr|C9JEY0|C9JEY0_HUMAN" 6 784.4443 0.86 58106 3558 2 784.442731 393.2294 "Trifunctional enzyme subunit beta, mitochondrial OS=Homo sapiens OX=9606 GN=HADHB PE=1 SV=3" 8.8 1350.2 - 1.61E+06 - - - -2.004 - 1.231 0.009 - 83.9 20 2 0 -0.0016 8 0 0 0 1.03E+08 1.20E+08 - - - -0.8474 0.9789 221125_WJC_METTL3_EV_vs_WT_F05.03561.03561.2 0.534 12-Jun R.GDESGYR.W "sp|Q8NEY8|PPHLN_HUMAN,tr|F8VRK2|F8VRK2_HUMAN,tr|F8VWU8|F8VWU8_HUMAN,tr|F8W0Q9|F8W0Q9_HUMAN,tr|F8VPY7|F8VPY7_HUMAN" 5 782.3195 2.03 58107 3561 2 782.316811 392.167 Periphilin-1 OS=Homo sapiens OX=9606 GN=PPHLN1 PE=1 SV=2 4.37 1350.6 - 1.84E+06 - - - -3.4321 - 1.333 0.191 - 236.9 1 2 0 -0.0027 7 0 0 0 6.25E+07 3.08E+07 - - - 1.3616 0.9998 221125_WJC_METTL3_EV_vs_WT_F05.03563.03563.2 0.00146 16-Oct K.QGVAEAAGK.T "sp|P37840|SYUA_HUMAN,tr|A0A669KB41|A0A669KB41_HUMAN,tr|D6RA31|D6RA31_HUMAN,tr|A0A669KBH5|A0A669KBH5_HUMAN,tr|H6UYS7|H6UYS7_HUMAN,tr|E7EPV7|E7EPV7_HUMAN" 6 829.4294 1.59 58108 3563 2 829.430329 415.722 Alpha-synuclein OS=Homo sapiens OX=9606 GN=SNCA PE=1 SV=1 6 1350.8 - 1.49E+07 - - - 1.143 - 2.062 0.487 - 487.9 1 2 0 0.0009 9 0 0 0 3.49E+09 2.19E+09 - - - 4.7313 0.9657 221125_WJC_METTL3_EV_vs_WT_F05.03568.03568.2 8.13 12-Jul K.STTNELK[136.11].S "sp|Q92878|RAD50_HUMAN,tr|A0A494C1B7|A0A494C1B7_HUMAN,tr|A0A1W2PQ90|A0A1W2PQ90_HUMAN" 3 799.4167 0.87 58111 3568 2 799.416479 400.7156 DNA repair protein RAD50 OS=Homo sapiens OX=9606 GN=RAD50 PE=1 SV=1 5.72 1351.4 - 1.04E+06 - - - -0.2739 - 1.264 0.003 - 195.3 1 2 0 -0.0002 7 0 0 0 3.35E+07 3.84E+07 - - - -0.1946 0.9507 221125_WJC_METTL3_EV_vs_WT_F05.03570.03570.2 1.19 12-Aug K.SVTVTQK.V "sp|P07197|NFM_HUMAN,tr|E7ESP9|E7ESP9_HUMAN,tr|E7EMV2|E7EMV2_HUMAN" 3 761.4283 1.78 58113 3570 2 761.42688 381.7214 Neurofilament medium polypeptide OS=Homo sapiens OX=9606 GN=NEFM PE=1 SV=3 8.47 1351.6 - 3.94E+06 - - - -1.8899 - 1.21 0.049 - 216.8 1 2 0 -0.0014 7 0 0 0 1.90E+08 1.07E+08 - - - 0.0065 0.9989 221125_WJC_METTL3_EV_vs_WT_F05.03575.03575.2 0.0043 12-Jul R.QC[160.03]EEVAR.A "sp|P51570|GALK1_HUMAN,tr|K7EII7|K7EII7_HUMAN" 2 890.3916 1.66 58116 3575 2 890.38976 446.2031 Galactokinase OS=Homo sapiens OX=9606 GN=GALK1 PE=1 SV=1 4.53 1352.2 - 4.85E+06 - - - -2.0845 - 1.376 0.409 - 209.1 1 2 0 -0.0019 7 0 0 0 1.26E+08 7.58E+07 - - - 3.0726 0.9676 221125_WJC_METTL3_EV_vs_WT_F05.03578.03578.2 0.28 12-Jun K.QNAELAK[136.11].L "sp|Q9P2E9|RRBP1_HUMAN,tr|A0A087WVV2|A0A087WVV2_HUMAN,tr|F8W7S5|F8W7S5_HUMAN" 3 780.4221 1.35 58117 3578 2 780.41995 391.2183 Ribosome-binding protein 1 OS=Homo sapiens OX=9606 GN=RRBP1 PE=1 SV=5 6 1352.6 - 3.03E+06 - - - -2.778 - 1.203 0.147 - 222.1 1 2 0 -0.0022 7 0 0 0 1.33E+08 9.88E+07 - - - 0.7117 0.9955 221125_WJC_METTL3_EV_vs_WT_F05.03587.03587.2 0.0761 16-Aug K.ALQTTGTAK.S "sp|P52948|NUP98_HUMAN,tr|A0A3B3ITD8|A0A3B3ITD8_HUMAN,tr|H0YEN4|H0YEN4_HUMAN,tr|H0YCR0|H0YCR0_HUMAN" 4 889.4869 1.68 58121 3587 2 889.483936 445.7507 Nuclear pore complex protein Nup98-Nup96 OS=Homo sapiens OX=9606 GN=NUP98 PE=1 SV=4 8.8 1353.7 - 9.20E+06 - - - -3.3278 - 1.448 0.333 - 182.4 1 2 0 -0.003 9 0 0 0 1.28E+09 7.59E+08 - - - 2.5706 0.9267 221125_WJC_METTL3_EV_vs_WT_F05.03595.03595.2 0.161 16-Sep K.ALQTTGTAK[136.11].S "sp|P52948|NUP98_HUMAN,tr|A0A3B3ITD8|A0A3B3ITD8_HUMAN,tr|H0YEN4|H0YEN4_HUMAN,tr|H0YCR0|H0YCR0_HUMAN" 4 897.5011 1.68 58124 3595 2 897.498389 449.7578 Nuclear pore complex protein Nup98-Nup96 OS=Homo sapiens OX=9606 GN=NUP98 PE=1 SV=4 8.8 1354.7 - 1.44E+07 - - - -3.0162 - 1.426 0.026 - 209.4 1 2 0 -0.0027 9 0 0 0 1.28E+09 7.59E+08 - - - 0.2589 0.9974 221125_WJC_METTL3_EV_vs_WT_F05.03599.03599.2 0.00815 16-Aug R.LGESANAAK.Q sp|Q9H9B4|SFXN1_HUMAN 1 859.4399 1.03 58126 3599 2 859.43735 430.7272 Sideroflexin-1 OS=Homo sapiens OX=9606 GN=SFXN1 PE=1 SV=4 6 1355.2 - 3.98E+06 - - - -3.0206 - 1.588 0.338 - 138 1 2 0 -0.0026 9 0 0 0 1.13E+08 1.09E+08 - - - 2.8746 0.9783 221125_WJC_METTL3_EV_vs_WT_F05.03611.03611.2 0.48 16-Jul R.EVAQTADAR[166.11].L "sp|P19174|PLCG1_HUMAN,tr|M0QX77|M0QX77_HUMAN,tr|A0A0D9SEK2|A0A0D9SEK2_HUMAN" 3 969.4755 0.58 58131 3611 2 969.471769 485.745 "1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma-1 OS=Homo sapiens OX=9606 GN=PLCG1 PE=1 SV=1" 4.37 1356.7 - 319033 - - - -3.8413 - 1.415 0.206 - 158.1 1 2 0 -0.0037 9 0 0 0 2.90E+06 4.98E+06 - - - 1.5656 0.9138 221125_WJC_METTL3_EV_vs_WT_F05.03615.03615.2 0.0377 16-Sep L.LAQAQAQAR.A "sp|P58107|EPIPL_HUMAN,sp|P58107|EPIPL_HUMAN,sp|P58107|EPIPL_HUMAN,sp|P58107|EPIPL_HUMAN,sp|P58107|EPIPL_HUMAN,tr|A0A075B730|A0A075B730_HUMAN,tr|A0A075B730|A0A075B730_HUMAN,tr|A0A075B730|A0A075B730_HUMAN,tr|A0A075B730|A0A075B730_HUMAN,tr|A0A075B730|A0A075B730_HUMAN" 10 955.5199 1.56 58133 3615 2 955.516815 478.7672 Epiplakin OS=Homo sapiens OX=9606 GN=EPPK1 PE=1 SV=3 9.75 1357.2 - 262903 - - - -3.2579 - 1.968 0.354 - 406 1 1 0 -0.0031 9 0 0 0 4.97E+06 3.18E+06 - - - 3.6133 0.8952 221125_WJC_METTL3_EV_vs_WT_F05.03626.03626.2 1.22 12-Jul R.HLGNAIK[136.11].Q "sp|Q99567|NUP88_HUMAN,tr|J3KMX1|J3KMX1_HUMAN" 2 759.4483 0.001 58139 3626 2 759.445553 380.7314 Nuclear pore complex protein Nup88 OS=Homo sapiens OX=9606 GN=NUP88 PE=1 SV=2 8.76 1358.4 - 3.03E+06 - - - -3.5815 - 1.355 0.055 - 149.8 2 2 0 -0.0027 7 0 0 0 0.00E+00 1.04E+08 - - - 0.2745 0.9695 221125_WJC_METTL3_EV_vs_WT_F05.03632.03632.2 0.0468 12-Sep R.ILKEEPK.G "sp|Q8WWM7|ATX2L_HUMAN,tr|H3BUF6|H3BUF6_HUMAN" 2 855.5066 1.51 58143 3632 2 855.504568 428.7606 Ataxin-2-like protein OS=Homo sapiens OX=9606 GN=ATXN2L PE=1 SV=2 6.14 1359.1 - 2.21E+06 - - - -2.339 - 1.496 0.276 - 246.1 1 2 1 -0.002 7 0 0 0 7.48E+07 4.95E+07 - - - 2.3552 0.9973 221125_WJC_METTL3_EV_vs_WT_F05.03633.03633.2 0.000108 16-Sep K.YVSGSSAER.R sp|Q6NTF9|RHBD2_HUMAN 1 954.4407 1 58144 3633 2 954.437564 478.2276 Rhomboid domain-containing protein 2 OS=Homo sapiens OX=9606 GN=RHBDD2 PE=1 SV=2 6 1359.3 - 711520 - - - -3.2585 - 1.826 0.301 - 207.2 1 2 0 -0.0031 9 0 0 0 1.23E+07 1.24E+07 - - - 3.0052 0.9915 221125_WJC_METTL3_EV_vs_WT_F05.03634.03634.2 0.0594 16-Jul K.YVSGSSAER[166.11].R sp|Q6NTF9|RHBD2_HUMAN 1 964.4489 1 58145 3634 2 964.447924 483.2317 Rhomboid domain-containing protein 2 OS=Homo sapiens OX=9606 GN=RHBDD2 PE=1 SV=2 6 1359.4 - 647759 - - - -1.0576 - 1.292 0.147 - 126.8 1 2 0 -0.001 9 0 0 0 1.23E+07 1.24E+07 - - - 0.8676 0.9883 221125_WJC_METTL3_EV_vs_WT_F05.03639.03639.2 0.0721 12-Jun K.VQDQMTK.Q sp|Q7Z3B4|NUP54_HUMAN 1 848.4062 1.44 58148 3639 2 848.40425 425.2104 Nucleoporin p54 OS=Homo sapiens OX=9606 GN=NUP54 PE=1 SV=2 5.81 1360 - 1.17E+06 - - - -2.302 - 1.274 0.188 - 89 1 2 0 -0.002 7 0 0 0 6.94E+07 4.81E+07 - - - 1.1963 0.9996 221125_WJC_METTL3_EV_vs_WT_F05.03640.03640.2 0.00233 12-Jul R.C[160.03]YEC[160.03]GEK.G "sp|Q16629|SRSF7_HUMAN,tr|C9JAB2|C9JAB2_HUMAN,tr|F8WEA1|F8WEA1_HUMAN,tr|A0A0B4J1Z1|A0A0B4J1Z1_HUMAN" 4 944.3368 1.93 58149 3640 2 944.335225 473.1757 Serine\arginine-rich splicing factor 7 OS=Homo sapiens OX=9606 GN=SRSF7 PE=1 SV=1 4.53 1360.2 - 384587 - - - -1.671 - 1.32 0.534 - 165.5 1 2 0 -0.0016 7 0 0 0 1.51E+07 7.83E+06 - - - 3.8643 0.9874 221125_WJC_METTL3_EV_vs_WT_F05.03648.03648.2 0.831 14-Aug R.TAQSGALR[166.11].D sp|P40222|TXLNA_HUMAN 1 812.438 1.65 58153 3648 2 812.435824 407.2263 Alpha-taxilin OS=Homo sapiens OX=9606 GN=TXLNA PE=1 SV=3 9.41 1361.2 - 2.69E+06 - - - -2.6611 - 1.546 0.132 - 321 1 2 0 -0.0022 8 0 0 0 8.86E+07 5.37E+07 - - - 1.3292 0.996 221125_WJC_METTL3_EV_vs_WT_F05.03649.03649.2 1.21 14-Jul K.ELQNAGDR.L "sp|Q15149|PLEC_HUMAN,tr|H0YDN1|H0YDN1_HUMAN" 2 901.4254 1.37 58154 3649 2 901.425462 451.72 Plectin OS=Homo sapiens OX=9606 GN=PLEC PE=1 SV=3 4.37 1361.3 - 1.77E+06 - - - 0.1143 - 1.396 0.166 - 190.2 1 2 0 0.0001 8 0 0 0 3.30E+07 2.41E+07 - - - 1.2732 0.9973 221125_WJC_METTL3_EV_vs_WT_F05.03663.03663.2 0.00413 16-Aug K.EVEETATAK.N "sp|Q9BPX3|CND3_HUMAN,tr|H0Y9Z8|H0Y9Z8_HUMAN" 2 976.4713 0.26 58160 3663 2 976.471289 489.2429 Condensin complex subunit 3 OS=Homo sapiens OX=9606 GN=NCAPG PE=1 SV=1 4.25 1363.1 - 226060 - - - -0.0174 - 1.324 0.229 - 260.2 1 2 0 0 9 0 0 0 7.61E+06 2.97E+07 - - - 1.5443 0.79 221125_WJC_METTL3_EV_vs_WT_F05.03665.03665.2 0.197 14-Jul K.VTTHPLAK[136.11].D "sp|Q99497|PARK7_HUMAN,tr|K7EN27|K7EN27_HUMAN,tr|K7ELW0|K7ELW0_HUMAN" 3 873.5164 2.13 58161 3665 2 873.51143 437.7655 Parkinson disease protein 7 OS=Homo sapiens OX=9606 GN=PARK7 PE=1 SV=2 8.73 1363.3 - 1.10E+06 - - - -5.6347 - 1.26 0.132 - 117.6 1 2 0 -0.0049 8 0 0 0 2.80E+08 1.32E+08 - - - 0.7114 0.9995 221125_WJC_METTL3_EV_vs_WT_F05.03671.03671.2 0.000913 14-Sep K.VTTHPLAK.D "sp|Q99497|PARK7_HUMAN,tr|K7EN27|K7EN27_HUMAN,tr|K7ELW0|K7ELW0_HUMAN" 3 865.5022 2.13 58164 3671 2 865.500003 433.7584 Parkinson disease protein 7 OS=Homo sapiens OX=9606 GN=PARK7 PE=1 SV=2 8.73 1364 - 2.56E+06 - - - -2.483 - 1.889 0.471 - 286.8 1 2 0 -0.0021 8 0 0 0 2.80E+08 1.32E+08 - - - 4.4374 0.9843 221125_WJC_METTL3_EV_vs_WT_F05.03674.03674.2 0.398 12-Jul K.LAEQAER.Y "sp|P31946|1433B_HUMAN,sp|P62258|1433E_HUMAN,sp|P27348|1433T_HUMAN,sp|P63104|1433Z_HUMAN,sp|Q04917|1433F_HUMAN,sp|P31947|1433S_HUMAN,sp|P61981|1433G_HUMAN,tr|E7EX29|E7EX29_HUMAN,tr|Q4VY19|Q4VY19_HUMAN,tr|B4DJF2|B4DJF2_HUMAN,tr|I3L0W5|I3L0W5_HUMAN,tr|Q4VY20|Q4VY20_HUMAN,tr|A2IDB1|A2IDB1_HUMAN,tr|E5RIR4|E5RIR4_HUMAN,tr|E9PG15|E9PG15_HUMAN,tr|I3L3T1|I3L3T1_HUMAN,tr|E7EVZ2|E7EVZ2_HUMAN,tr|F8WEB6|F8WEB6_HUMAN,tr|E5RGE1|E5RGE1_HUMAN,tr|E9PD24|E9PD24_HUMAN,tr|A0A0J9YWE8|A0A0J9YWE8_HUMAN,tr|E7ESK7|E7ESK7_HUMAN" 22 815.4137 1.46 58165 3674 2 815.412013 408.7141 14-3-3 protein beta\alpha OS=Homo sapiens OX=9606 GN=YWHAB PE=1 SV=3 4.53 1364.4 - 2.32E+06 - - - -2.1069 - 1.513 0.072 - 207.8 1 2 0 -0.0017 7 0 0 0 7.05E+07 4.83E+07 - - - 0.8843 0.9862 221125_WJC_METTL3_EV_vs_WT_F05.03676.03676.2 0.0552 20-Jul R.APGAAPSAAAK[136.11].S sp|Q9BXK1|KLF16_HUMAN 1 918.5014 3.91 58166 3676 2 918.498897 460.258 Krueppel-like factor 16 OS=Homo sapiens OX=9606 GN=KLF16 PE=1 SV=1 8.8 1364.6 - 524537 - - - -2.7578 - 1.563 0.181 - 122.8 4 2 0 -0.0025 11 0 0 0 2.03E+08 5.19E+07 - - - 1.3163 0.8115 221125_WJC_METTL3_EV_vs_WT_F05.03687.03687.2 0.0118 12-Aug V.TTHPLAK[136.11].D "sp|Q99497|PARK7_HUMAN,tr|K7EN27|K7EN27_HUMAN,tr|K7ELW0|K7ELW0_HUMAN" 3 774.4479 1.79 58170 3687 2 774.445206 388.2312 Parkinson disease protein 7 OS=Homo sapiens OX=9606 GN=PARK7 PE=1 SV=2 8.44 1366.1 - 9.57E+06 - - - -3.5277 - 1.459 0.356 - 308.2 1 1 0 -0.0027 7 0 0 0 4.27E+08 2.39E+08 - - - 2.8665 0.8801 221125_WJC_METTL3_EV_vs_WT_F05.03701.03701.2 1.89 14-May K.SLESQGGR[166.11].R "sp|Q2TBE0|C19L2_HUMAN,tr|H0YE03|H0YE03_HUMAN,tr|H7C3G7|H7C3G7_HUMAN" 3 842.4122 1.42 58178 3701 2 842.409227 422.2134 CWF19-like protein 2 OS=Homo sapiens OX=9606 GN=CWF19L2 PE=1 SV=4 5.72 1367.8 - 692654 - - - -3.4876 - 1.176 0.118 - 69.5 4 2 0 -0.0029 8 0 0 0 6.78E+07 4.78E+07 - - - 0.1316 0.9996 221125_WJC_METTL3_EV_vs_WT_F05.03702.03702.2 0.0313 20-Nov R.APGAAPSAAAK.S sp|Q9BXK1|KLF16_HUMAN 1 910.4872 1.14 58179 3702 2 910.487356 456.2509 Krueppel-like factor 16 OS=Homo sapiens OX=9606 GN=KLF16 PE=1 SV=1 8.8 1367.9 - 1.75E+06 - - - 0.1373 - 1.978 0.319 - 370.9 1 2 0 0.0001 11 0 0 0 4.45E+07 3.91E+07 - - - 3.2423 0.9971 221125_WJC_METTL3_EV_vs_WT_F05.03705.03705.2 0.124 12-Sep R.C[160.03]VAEEER[166.11].G "sp|O15067|PUR4_HUMAN,tr|H0YGH1|H0YGH1_HUMAN" 2 901.3839 0.98 58180 3705 2 901.381139 451.6992 Phosphoribosylformylglycinamidine synthase OS=Homo sapiens OX=9606 GN=PFAS PE=1 SV=4 4.25 1368.3 - 1.04E+06 - - - -3.0642 - 1.697 0.285 - 352.2 1 2 0 -0.0028 7 0 0 0 2.08E+07 2.12E+07 - - - 2.8209 0.9966 221125_WJC_METTL3_EV_vs_WT_F05.03711.03711.2 0.0825 12-Aug R.NDEELNK.L "sp|P16104|H2AX_HUMAN,sp|Q9BTM1|H2AJ_HUMAN,sp|Q93077|H2A1C_HUMAN,sp|Q99878|H2A1J_HUMAN,sp|Q16777|H2A2C_HUMAN,sp|Q8IUE6|H2A2B_HUMAN,sp|Q96QV6|H2A1A_HUMAN,sp|P04908|H2A1B_HUMAN,sp|P20671|H2A1D_HUMAN,sp|P0C0S8|H2A1_HUMAN,sp|Q6FI13|H2A2A_HUMAN,sp|Q96KK5|H2A1H_HUMAN,sp|Q7L7L0|H2A3_HUMAN,tr|A0A0U1RR32|A0A0U1RR32_HUMAN,tr|A0A0U1RRH7|A0A0U1RRH7_HUMAN,tr|A0A3B3IS11|A0A3B3IS11_HUMAN,tr|H0YFX9|H0YFX9_HUMAN" 17 860.3876 1.28 58183 3711 2 860.385085 431.2011 Histone H2AX OS=Homo sapiens OX=9606 GN=H2AX PE=1 SV=2 4.14 1368.9 - 3.05E+06 - - - -2.8952 - 1.529 0.292 - 392.9 1 2 0 -0.0025 7 0 0 0 9.87E+08 7.68E+08 - - - 2.5423 0.9678 221125_WJC_METTL3_EV_vs_WT_F05.03713.03713.2 1.04 12-Jul K.TLDSQTR.T "sp|P46379|BAG6_HUMAN,tr|F6UR09|F6UR09_HUMAN,tr|A0A7I2V508|A0A7I2V508_HUMAN,tr|F6U1F2|F6U1F2_HUMAN,tr|F6U341|F6U341_HUMAN,tr|F6WML8|F6WML8_HUMAN,tr|A0A0G2JJM1|A0A0G2JJM1_HUMAN,tr|X6REW1|X6REW1_HUMAN,tr|A0A7I2V3H1|A0A7I2V3H1_HUMAN,tr|A0A7P0MQS5|A0A7P0MQS5_HUMAN,tr|F6XTU0|F6XTU0_HUMAN,tr|F6X9W3|F6X9W3_HUMAN,tr|F6VEM6|F6VEM6_HUMAN,tr|A0A0G2JJR8|A0A0G2JJR8_HUMAN,tr|F6S6P2|F6S6P2_HUMAN,tr|F6TC96|F6TC96_HUMAN,tr|A0A0G2JL47|A0A0G2JL47_HUMAN,tr|A0A024RCR6|A0A024RCR6_HUMAN,tr|A0A0G2JK23|A0A0G2JK23_HUMAN,tr|A0A1B0GX79|A0A1B0GX79_HUMAN" 20 819.4086 1.46 58185 3713 2 819.40628 410.7116 Large proline-rich protein BAG6 OS=Homo sapiens OX=9606 GN=BAG6 PE=1 SV=2 5.5 1369.1 - 1.32E+06 - - - -2.8874 - 0.946 0.258 - 172.4 1 2 0 -0.0024 7 0 0 0 2.92E+08 2.00E+08 - - - 0.7699 0.9971 221125_WJC_METTL3_EV_vs_WT_F05.03719.03719.2 0.0123 12-Jul R.NDEELNK[136.11].L "sp|P16104|H2AX_HUMAN,sp|Q9BTM1|H2AJ_HUMAN,sp|Q93077|H2A1C_HUMAN,sp|Q99878|H2A1J_HUMAN,sp|Q16777|H2A2C_HUMAN,sp|Q8IUE6|H2A2B_HUMAN,sp|Q96QV6|H2A1A_HUMAN,sp|P04908|H2A1B_HUMAN,sp|P20671|H2A1D_HUMAN,sp|P0C0S8|H2A1_HUMAN,sp|Q6FI13|H2A2A_HUMAN,sp|Q96KK5|H2A1H_HUMAN,sp|Q7L7L0|H2A3_HUMAN,tr|A0A0U1RR32|A0A0U1RR32_HUMAN,tr|A0A0U1RRH7|A0A0U1RRH7_HUMAN,tr|A0A3B3IS11|A0A3B3IS11_HUMAN,tr|H0YFX9|H0YFX9_HUMAN" 17 868.4018 1.31 58188 3719 2 868.399524 435.2082 Histone H2AX OS=Homo sapiens OX=9606 GN=H2AX PE=1 SV=2 4.14 1369.7 - 6.60E+06 - - - -2.5933 - 1.474 0.301 - 293.7 1 2 0 -0.0023 7 0 0 0 9.85E+08 7.49E+08 - - - 2.4928 0.7754 221125_WJC_METTL3_EV_vs_WT_F05.03723.03723.2 2.41 12-May R.ITEVQQK.R "sp|Q13868|EXOS2_HUMAN,tr|A3KFL1|A3KFL1_HUMAN,tr|A3KFL2|A3KFL2_HUMAN,tr|A3KFL5|A3KFL5_HUMAN" 4 844.4654 0.89 58192 3723 2 844.462793 423.24 Exosome complex component RRP4 OS=Homo sapiens OX=9606 GN=EXOSC2 PE=1 SV=2 6 1370.1 - 329458 - - - -3.1251 - 1.204 0.051 - 55.9 14 2 0 -0.0026 7 0 0 0 9.31E+07 1.05E+08 - - - -0.5069 0.9184 221125_WJC_METTL3_EV_vs_WT_F05.03739.03739.2 1.11 12-May K.RGEIIAK.Q "sp|P52272|HNRPM_HUMAN,tr|M0R019|M0R019_HUMAN,tr|K7EQF1|K7EQF1_HUMAN,tr|A0A087X0X3|A0A087X0X3_HUMAN,tr|M0R2T0|M0R2T0_HUMAN" 5 785.4759 1.67 58196 3739 2 785.473932 393.7452 Heterogeneous nuclear ribonucleoprotein M OS=Homo sapiens OX=9606 GN=HNRNPM PE=1 SV=3 8.75 1372.5 - 929796 - - - -2.5539 - 1.376 0.063 - 87.4 17 2 0 -0.002 7 0 0 0 2.27E+09 1.36E+09 - - - -0.0326 0.9545 221125_WJC_METTL3_EV_vs_WT_F05.03753.03753.2 0.303 16-Jul R.QAAEVAAEK[136.11].S sp|Q9NW64|RBM22_HUMAN 1 923.4804 0.76 58203 3753 2 923.476848 462.7475 Pre-mRNA-splicing factor RBM22 OS=Homo sapiens OX=9606 GN=RBM22 PE=1 SV=1 4.53 1374.2 - 269061 - - - -3.8041 - 1.156 0.207 - 152.5 1 2 0 -0.0035 9 0 0 0 1.35E+08 1.78E+08 - - - 0.9882 0.999 221125_WJC_METTL3_EV_vs_WT_F05.03766.03766.2 0.00105 16-Aug R.QAAEVAAEK.S sp|Q9NW64|RBM22_HUMAN 1 915.4662 0.76 58206 3766 2 915.464608 458.7404 Pre-mRNA-splicing factor RBM22 OS=Homo sapiens OX=9606 GN=RBM22 PE=1 SV=1 4.53 1376.2 - 704137 - - - -1.6964 - 1.608 0.336 - 199 1 2 0 -0.0016 9 0 0 0 1.35E+08 1.78E+08 - - - 2.8964 0.991 221125_WJC_METTL3_EV_vs_WT_F05.03770.03770.2 0.927 12-Jun R.STGETIR[166.11].S "sp|P17987|TCPA_HUMAN,tr|F5GZ03|F5GZ03_HUMAN,tr|F5GZI8|F5GZI8_HUMAN,tr|E7ERF2|E7ERF2_HUMAN,tr|F5GYL4|F5GYL4_HUMAN" 5 772.3955 0.43 58208 3770 2 772.394032 387.205 T-complex protein 1 subunit alpha OS=Homo sapiens OX=9606 GN=TCP1 PE=1 SV=1 5.72 1376.7 - 7.72E+06 - - - -1.8384 - 1.452 0.125 - 215.5 1 2 0 -0.0014 7 0 0 0 1.53E+09 3.53E+09 - - - 1.1455 0.9823 221125_WJC_METTL3_EV_vs_WT_F05.03775.03775.2 2.98 12-Jul K.QALQGER[166.11].E sp|P07196|NFL_HUMAN 1 810.4223 3.19 58211 3775 2 810.421805 406.2184 Neurofilament light polypeptide OS=Homo sapiens OX=9606 GN=NEFL PE=1 SV=3 6 1377.2 - 1.23E+06 - - - -0.6552 - 1.277 0.081 - 194.9 2 2 0 -0.0005 7 0 0 0 7.56E+08 2.37E+08 - - - 0.2794 0.9865 221125_WJC_METTL3_EV_vs_WT_F05.03780.03780.2 0.532 14-May R.LSPATENK[136.11].L "sp|Q8N1F7|NUP93_HUMAN,tr|H3BPA9|H3BPA9_HUMAN,tr|H3BVG0|H3BVG0_HUMAN" 3 866.4589 2.42 58213 3780 2 866.458442 434.2367 Nuclear pore complex protein Nup93 OS=Homo sapiens OX=9606 GN=NUP93 PE=1 SV=2 6 1377.8 - 2.03E+06 - - - -0.5251 - 1.251 0.134 - 94.5 4 2 0 -0.0005 8 0 0 0 1.43E+08 5.92E+07 - - - 0.437 0.9988 221125_WJC_METTL3_EV_vs_WT_F05.03787.03787.2 0.0936 14-Jul R.LSPATENK.L "sp|Q8N1F7|NUP93_HUMAN,tr|H3BPA9|H3BPA9_HUMAN,tr|H3BVG0|H3BVG0_HUMAN" 3 858.4447 2.33 58216 3787 2 858.443236 430.2296 Nuclear pore complex protein Nup93 OS=Homo sapiens OX=9606 GN=NUP93 PE=1 SV=2 6 1378.7 - 2.41E+06 - - - -1.7019 - 1.474 0.342 - 182.7 1 2 0 -0.0015 8 0 0 0 1.43E+08 6.16E+07 - - - 2.7367 0.9917 221125_WJC_METTL3_EV_vs_WT_F05.03793.03793.2 0.271 14-Jul R.LQPGDTAK.A sp|O94906|PRP6_HUMAN 1 828.4341 1.19 58220 3793 2 828.432691 415.2243 Pre-mRNA-processing factor 6 OS=Homo sapiens OX=9606 GN=PRPF6 PE=1 SV=1 5.84 1379.4 - 1.17E+06 - - - -1.7394 - 1.333 0.198 - 159.8 3 2 0 -0.0014 8 0 0 0 1.05E+08 8.84E+07 - - - 1.1567 0.9684 221125_WJC_METTL3_EV_vs_WT_F05.03804.03804.2 0.135 12-Jun K.ILEEDHK[136.11].G "sp|Q9NRA8|4ET_HUMAN,tr|B1AKL4|B1AKL4_HUMAN" 2 890.4589 0.65 58225 3804 2 890.455456 446.2367 Eukaryotic translation initiation factor 4E transporter OS=Homo sapiens OX=9606 GN=EIF4ENIF1 PE=1 SV=2 4.65 1380.8 - 3.62E+06 - - - -3.8643 - 1.169 0.238 - 98.1 1 2 0 -0.0034 7 0 0 0 1.86E+08 2.85E+08 - - - 1.2926 0.9246 221125_WJC_METTL3_EV_vs_WT_F05.03807.03807.2 1.85 18-Jun R.GTVVAQGGGR.A "sp|Q9H3U1|UN45A_HUMAN,tr|A0A1W2PNX8|A0A1W2PNX8_HUMAN" 2 900.4777 0.23 58226 3807 2 900.476877 451.2461 Protein unc-45 homolog A OS=Homo sapiens OX=9606 GN=UNC45A PE=1 SV=1 9.75 1381.2 - 590830 - - - -0.9451 - 1.055 0.09 - 63.2 11 2 0 -0.0009 10 0 0 0 3.41E+07 1.45E+08 - - - -0.6103 0.9963 221125_WJC_METTL3_EV_vs_WT_F05.03833.03833.2 0.151 14-Aug K.TGTLTQNR[166.11].M "sp|P05023|AT1A1_HUMAN,sp|P13637|AT1A3_HUMAN,sp|Q13733|AT1A4_HUMAN,sp|P50993|AT1A2_HUMAN,sp|P54707|AT12A_HUMAN,sp|P20648|ATP4A_HUMAN,tr|A0A669K9X0|A0A669K9X0_HUMAN,tr|A0A0A0MT26|A0A0A0MT26_HUMAN,tr|H0Y7C1|H0Y7C1_HUMAN,tr|A0A2R8YEY8|A0A2R8YEY8_HUMAN,tr|E9PRA5|E9PRA5_HUMAN,tr|B1AKY9|B1AKY9_HUMAN,tr|M0R116|M0R116_HUMAN" 13 899.47 1.29 58239 3833 2 899.469481 450.7423 Sodium\potassium-transporting ATPase subunit alpha-1 OS=Homo sapiens OX=9606 GN=ATP1A1 PE=1 SV=1 9.41 1384.3 - 4.05E+06 - - - -0.5926 - 1.083 0.281 - 118.5 1 2 0 -0.0005 8 0 0 0 8.52E+07 6.61E+07 - - - 1.3568 0.9958 221125_WJC_METTL3_EV_vs_WT_F05.03839.03839.2 0.299 16-Sep K.IAAEEQTAK.R sp|Q9H875|PKRI1_HUMAN 1 959.4924 0.68 58241 3839 2 959.489835 480.7535 PRKR-interacting protein 1 OS=Homo sapiens OX=9606 GN=PRKRIP1 PE=1 SV=1 4.53 1385.1 - 1.05E+06 - - - -2.6472 - 1.616 0.24 - 205 1 2 0 -0.0025 9 0 0 0 2.10E+07 3.09E+07 - - - 2.2014 0.9467 221125_WJC_METTL3_EV_vs_WT_F05.03843.03843.2 0.0922 16-Jun K.AVQADGQVK[136.11].E sp|Q8WUM4|PDC6I_HUMAN 1 922.4963 0.89 58243 3843 2 922.49283 462.2554 Programmed cell death 6-interacting protein OS=Homo sapiens OX=9606 GN=PDCD6IP PE=1 SV=1 5.88 1385.6 - 1.61E+06 - - - -3.8103 - 1.446 0.167 - 107.6 11 2 0 -0.0035 9 0 0 0 2.99E+07 3.37E+07 - - - 0.8751 0.9969 221125_WJC_METTL3_EV_vs_WT_F05.03847.03847.2 0.00477 12-Jul K.QESTEYR.R "sp|P08670|VIME_HUMAN,tr|B0YJC5|B0YJC5_HUMAN,tr|B0YJC4|B0YJC4_HUMAN" 3 911.3985 2.77 58245 3847 2 911.395687 456.7065 Vimentin OS=Homo sapiens OX=9606 GN=VIM PE=1 SV=4 4.53 1386.1 - 3.90E+06 - - - -3.059 - 1.276 0.396 - 118.9 1 2 0 -0.0028 7 0 0 0 6.94E+07 2.51E+07 - - - 2.7373 0.8603 221125_WJC_METTL3_EV_vs_WT_F05.03860.03860.2 0.105 16-Aug K.LVQSAQNER[166.11].E "sp|Q8NG31|KNL1_HUMAN,tr|H0YEY7|H0YEY7_HUMAN,tr|H0YCZ2|H0YCZ2_HUMAN" 3 1053.5442 0.23 58253 3860 2 1053.539362 527.7794 Kinetochore scaffold 1 OS=Homo sapiens OX=9606 GN=KNL1 PE=1 SV=3 6 1387.6 - 319378 - - - -4.632 - 1.416 0.07 - 165.2 1 2 0 -0.0049 9 0 0 0 1.64E+06 7.19E+06 - - - 0.5628 0.9131 221125_WJC_METTL3_EV_vs_WT_F05.03867.03867.2 4.56 12-Jun R.EQLDSGR[166.11].L sp|Q8WUA2|PPIL4_HUMAN 1 813.3856 0.95 58256 3867 2 813.384226 407.7001 Peptidyl-prolyl cis-trans isomerase-like 4 OS=Homo sapiens OX=9606 GN=PPIL4 PE=1 SV=1 4.37 1388.4 - 1.87E+06 - - - -1.7089 - 1.164 0.051 - 145.7 6 2 0 -0.0014 7 0 0 0 6.75E+07 7.07E+07 - - - -0.4492 0.9987 221125_WJC_METTL3_EV_vs_WT_F05.03878.03878.2 0.0361 16-Aug R.IEGTQADTR.E "sp|O60645|EXOC3_HUMAN,tr|D6RB59|D6RB59_HUMAN,tr|H0Y995|H0Y995_HUMAN" 3 989.4778 0.93 58263 3878 2 989.476468 495.7462 Exocyst complex component 3 OS=Homo sapiens OX=9606 GN=EXOC3 PE=1 SV=3 4.37 1389.6 - 419314 - - - -1.334 - 1.414 0.329 - 128.5 1 2 0 -0.0013 9 0 0 0 1.44E+07 1.56E+07 - - - 2.4728 0.9952 221125_WJC_METTL3_EV_vs_WT_F05.03879.03879.2 0.382 12-Jun K.SPSPVQR[166.11].L "sp|P42694|HELZ_HUMAN,tr|J3QS41|J3QS41_HUMAN" 2 779.4165 0.19 58264 3879 2 779.415716 390.7155 Probable helicase with zinc finger domain OS=Homo sapiens OX=9606 GN=HELZ PE=1 SV=2 9.47 1389.6 - 7.43E+06 - - - -1.0341 - 1.315 0.184 - 141.5 1 2 0 -0.0008 7 0 0 0 9.97E+06 5.38E+07 - - - 1.2674 0.9953 221125_WJC_METTL3_EV_vs_WT_F05.03881.03881.2 0.227 16-Aug R.IEGTQADTR[166.11].E "sp|O60645|EXOC3_HUMAN,tr|D6RB59|D6RB59_HUMAN,tr|H0Y995|H0Y995_HUMAN" 3 999.4861 0.93 58266 3881 2 999.483319 500.7503 Exocyst complex component 3 OS=Homo sapiens OX=9606 GN=EXOC3 PE=1 SV=3 4.37 1389.9 - 551002 - - - -2.7404 - 1.574 0.245 - 178.1 1 2 0 -0.0027 9 0 0 0 1.44E+07 1.56E+07 - - - 2.1621 0.9906 221125_WJC_METTL3_EV_vs_WT_F05.03887.03887.2 0.714 12-Jun K.ELAQTTR[166.11].T "sp|P50990|TCPQ_HUMAN,tr|H7C4C8|H7C4C8_HUMAN" 2 827.4377 0.29 58268 3887 2 827.436596 414.7261 T-complex protein 1 subunit theta OS=Homo sapiens OX=9606 GN=CCT8 PE=1 SV=4 6.1 1390.7 - 1.49E+06 - - - -1.275 - 1.402 0.103 - 206 1 2 0 -0.0011 7 0 0 0 3.81E+07 1.30E+08 - - - 0.8721 0.9993 221125_WJC_METTL3_EV_vs_WT_F05.03890.03890.2 0.00124 14-Aug K.APEPTDAR[166.11].K "sp|O43719|HTSF1_HUMAN,tr|Q5H919|Q5H919_HUMAN,tr|Q5H918|Q5H918_HUMAN" 3 865.4169 1.22 58269 3890 2 865.415671 433.7157 HIV Tat-specific factor 1 OS=Homo sapiens OX=9606 GN=HTATSF1 PE=1 SV=1 4.37 1391.1 - 1.24E+06 - - - -1.4386 - 1.538 0.378 - 318.7 1 2 0 -0.0012 8 0 0 0 6.15E+07 5.02E+07 - - - 3.1308 0.992 221125_WJC_METTL3_EV_vs_WT_F05.03897.03897.2 0.125 12-Sep K.TTHLIAK[136.11].E sp|O00232|PSD12_HUMAN 1 790.4792 0.66 58273 3897 2 790.477789 396.2469 26S proteasome non-ATPase regulatory subunit 12 OS=Homo sapiens OX=9606 GN=PSMD12 PE=1 SV=3 8.44 1391.9 - 1.19E+06 - - - -1.8331 - 1.333 0.174 - 287.2 1 2 0 -0.0014 7 0 0 0 1.87E+07 2.85E+07 - - - 1.2365 0.8703 221125_WJC_METTL3_EV_vs_WT_F05.03902.03902.2 0.0583 14-Jul C.TGSAINSR.E "sp|Q04759|KPCT_HUMAN,tr|A0A087X0I9|A0A087X0I9_HUMAN" 2 804.409 3.45 58276 3902 2 804.407226 403.2118 Protein kinase C theta type OS=Homo sapiens OX=9606 GN=PRKCQ PE=1 SV=3 9.41 1392.4 - 2.09E+06 - - - -2.1805 - 1.53 0.276 - 189.7 1 1 0 -0.0018 8 0 0 0 4.48E+07 1.30E+07 - - - 2.3616 0.8548 221125_WJC_METTL3_EV_vs_WT_F05.03909.03909.2 2.87 14-May K.SLSAQEEK.L "sp|Q13813|SPTN1_HUMAN,tr|A0A0D9SF54|A0A0D9SF54_HUMAN,tr|A0A0D9SGF6|A0A0D9SGF6_HUMAN" 3 890.4345 0.89 58279 3909 2 890.431907 446.2245 "Spectrin alpha chain, non-erythrocytic 1 OS=Homo sapiens OX=9606 GN=SPTAN1 PE=1 SV=3" 4.53 1393.3 - 3.47E+06 - - - -2.9413 - 1.164 0.051 - 59.9 2 2 0 -0.0026 8 0 0 0 6.14E+07 6.90E+07 - - - -0.2596 0.9947 221125_WJC_METTL3_EV_vs_WT_F05.03914.03914.2 0.11 12-Jul R.LC[160.03]NNMQK.A "sp|Q15020|SART3_HUMAN,tr|A0A499FI31|A0A499FI31_HUMAN" 2 906.4052 0.79 58281 3914 2 906.40322 454.2099 Squamous cell carcinoma antigen recognized by T-cells 3 OS=Homo sapiens OX=9606 GN=SART3 PE=1 SV=1 8.22 1393.9 - 625137 - - - -2.137 - 1.283 0.254 - 101.4 1 2 0 -0.0019 7 0 0 0 1.19E+07 1.51E+07 - - - 1.706 0.8751 221125_WJC_METTL3_EV_vs_WT_F05.03923.03923.2 0.311 14-Jul R.TATEC[160.03]DVR[166.11].M "sp|Q69YQ0|CYTSA_HUMAN,tr|C9J8U1|C9J8U1_HUMAN,tr|C9JLY8|C9JLY8_HUMAN,tr|A0A494C1J1|A0A494C1J1_HUMAN,tr|F8WAN1|F8WAN1_HUMAN" 5 960.421 0.41 58285 3923 2 960.414508 481.2178 Cytospin-A OS=Homo sapiens OX=9606 GN=SPECC1L PE=1 SV=2 4.37 1395.2 - 314497 - - - -6.7752 - 1.013 0.359 - 123.6 1 2 0 -0.0065 8 0 0 0 2.89E+06 7.05E+06 - - - 1.7295 0.9992 221125_WJC_METTL3_EV_vs_WT_F05.03924.03924.2 0.101 16-Sep K.QGVTEAAEK.T "sp|O76070|SYUG_HUMAN,sp|Q16143|SYUB_HUMAN,tr|F8W754|F8W754_HUMAN,tr|G4Y816|G4Y816_HUMAN" 4 931.4611 1.56 58286 3924 2 931.459519 466.7378 Gamma-synuclein OS=Homo sapiens OX=9606 GN=SNCG PE=1 SV=2 4.53 1395.2 - 4.95E+06 - - - -1.6705 - 1.945 0.287 - 370.1 1 2 0 -0.0016 9 0 0 0 1.01E+09 6.45E+08 - - - 3.0849 0.9624 221125_WJC_METTL3_EV_vs_WT_F05.03925.03925.2 1.63 12-May K.MLKPTGR.V "sp|Q9Y2L1|RRP44_HUMAN,tr|F2Z2C0|F2Z2C0_HUMAN,tr|G3V1J5|G3V1J5_HUMAN" 3 801.4531 1.24 58287 3925 2 801.451797 401.7338 Exosome complex exonuclease RRP44 OS=Homo sapiens OX=9606 GN=DIS3 PE=1 SV=2 11 1395.3 - 1.55E+06 - - - -1.6183 - 1.12 0.142 - 101.4 7 2 0 -0.0013 7 0 0 0 3.65E+07 2.95E+07 - - - 0.071 0.9423 221125_WJC_METTL3_EV_vs_WT_F05.03926.03926.2 0.931 12-Jul K.TFTSSEK[136.11].S "sp|Q8ND83|SLAI1_HUMAN,tr|A0A0A0MSS3|A0A0A0MSS3_HUMAN,tr|Q5T6P5|Q5T6P5_HUMAN" 3 806.3901 1.78 58288 3926 2 806.388635 404.2024 SLAIN motif-containing protein 1 OS=Homo sapiens OX=9606 GN=SLAIN1 PE=1 SV=3 5.66 1395.3 - 1.50E+06 - - - -1.8775 - 1.253 0.019 - 181.7 1 2 0 -0.0015 7 0 0 0 7.63E+07 4.29E+07 - - - -0.1045 0.9997 221125_WJC_METTL3_EV_vs_WT_F05.03928.03928.2 9.67E-05 18-Sep K.LDDANDAGGR.N sp|P11388|TOP2A_HUMAN 1 1002.4367 1.32 58290 3928 2 1002.435399 502.2256 DNA topoisomerase 2-alpha OS=Homo sapiens OX=9606 GN=TOP2A PE=1 SV=3 3.93 1395.6 - 131514 - - - -1.25 - 1.893 0.448 - 201.4 1 2 0 -0.0013 10 0 0 0 8.26E+06 6.24E+06 - - - 4.1308 0.9988 221125_WJC_METTL3_EV_vs_WT_F05.03931.03931.2 0.2 12-Aug M.PENVAPR[166.11].S sp|P50991|TCPD_HUMAN 1 791.4165 0.85 58291 3931 2 791.414868 396.7155 T-complex protein 1 subunit delta OS=Homo sapiens OX=9606 GN=CCT4 PE=1 SV=4 6.43 1396 - 2.45E+06 - - - -2.0899 - 1.857 0.263 - 207.4 1 2 0 -0.0017 7 0 0 0 5.03E+07 5.89E+07 - - - 2.9442 0.9722 221125_WJC_METTL3_EV_vs_WT_F05.03932.03932.2 0.853 12-Jun R.ELTNDER[166.11].K sp|O15226|NKRF_HUMAN 1 885.4067 0.74 58292 3932 2 885.404119 443.7106 NF-kappa-B-repressing factor OS=Homo sapiens OX=9606 GN=NKRF PE=1 SV=2 4.14 1396 - 1.99E+06 - - - -2.9659 - 1.332 0.131 - 226.5 1 2 0 -0.0026 7 0 0 0 5.29E+07 7.14E+07 - - - 0.9161 0.9455 221125_WJC_METTL3_EV_vs_WT_F05.03933.03933.2 0.0151 12-Jul K.TFTSSEK.S "sp|Q8ND83|SLAI1_HUMAN,tr|A0A0A0MSS3|A0A0A0MSS3_HUMAN,tr|Q5T6P5|Q5T6P5_HUMAN" 3 798.3759 1.71 58293 3933 2 798.373345 400.1953 SLAIN motif-containing protein 1 OS=Homo sapiens OX=9606 GN=SLAIN1 PE=1 SV=3 5.66 1396.1 - 1.98E+06 - - - -3.2616 - 1.345 0.082 - 173.2 1 2 0 -0.0026 7 0 0 0 7.88E+07 4.61E+07 - - - 0.585 0.9949 221125_WJC_METTL3_EV_vs_WT_F05.03934.03934.2 0.0252 16-Jul K.YVAGETNAK.E "sp|Q9NRY5|F1142_HUMAN,tr|E7ESJ7|E7ESJ7_HUMAN,tr|E5RGF9|E5RGF9_HUMAN,tr|E5RFK2|E5RFK2_HUMAN" 4 951.4662 1.17 58294 3934 2 951.464137 476.7404 Protein FAM114A2 OS=Homo sapiens OX=9606 GN=FAM114A2 PE=1 SV=4 6 1396.2 - 1.13E+06 - - - -2.1272 - 1.067 0.339 - 131.9 1 2 0 -0.002 9 0 0 0 2.29E+08 1.96E+08 - - - 1.7318 0.9367 221125_WJC_METTL3_EV_vs_WT_F05.03939.03939.2 0.0279 12-Jun T.C[160.03]TNQELR.A "sp|Q9BQ04|RBM4B_HUMAN,tr|E9PM61|E9PM61_HUMAN,tr|U3KQD5|U3KQD5_HUMAN,tr|E9PLB0|E9PLB0_HUMAN" 4 919.4182 1.86 58297 3939 2 919.418167 460.7164 RNA-binding protein 4B OS=Homo sapiens OX=9606 GN=RBM4B PE=1 SV=1 5.99 1396.8 - 555025 - - - 0.0022 - 1.401 0.292 - 154.6 1 1 0 0 7 0 0 0 1.70E+07 9.16E+06 - - - 2.2661 0.7933 221125_WJC_METTL3_EV_vs_WT_F05.03945.03945.2 1.25 12-Jun R.TQDLTAK.L sp|Q86XL3|ANKL2_HUMAN 1 775.4076 1.91 58300 3945 2 775.405271 388.7111 Ankyrin repeat and LEM domain-containing protein 2 OS=Homo sapiens OX=9606 GN=ANKLE2 PE=1 SV=4 5.5 1397.5 - 2.77E+06 - - - -2.9817 - 0.903 0.105 - 88.1 1 2 0 -0.0023 7 0 0 0 6.66E+07 3.50E+07 - - - -0.5075 0.984 221125_WJC_METTL3_EV_vs_WT_F05.03946.03946.2 0.0239 12-Jul R.SYSPDGK[136.11].E "sp|P43243|MATR3_HUMAN,tr|B3KM87|B3KM87_HUMAN,tr|A8MXP9|A8MXP9_HUMAN,tr|A0A0R4J2E8|A0A0R4J2E8_HUMAN,tr|D6REM6|D6REM6_HUMAN" 5 760.3483 0.001 58301 3946 2 760.345406 381.1814 Matrin-3 OS=Homo sapiens OX=9606 GN=MATR3 PE=1 SV=2 5.55 1397.5 - 1.17E+06 - - - -3.7851 - 1.238 0.279 - 211.5 1 2 0 -0.0029 7 0 0 0 0.00E+00 2.27E+07 - - - 1.7773 0.9995 221125_WJC_METTL3_EV_vs_WT_F05.03947.03947.2 0.0113 14-Aug R.TQAVVSGR.R "sp|Q96MU7|YTDC1_HUMAN,tr|J3QR07|J3QR07_HUMAN" 2 816.4454 1.69 58302 3947 2 816.444882 409.23 YTH domain-containing protein 1 OS=Homo sapiens OX=9606 GN=YTHDC1 PE=1 SV=3 9.41 1397.6 - 2.63E+06 - - - -0.5928 - 1.844 0.287 - 359.4 1 2 0 -0.0005 8 0 0 0 5.40E+07 3.19E+07 - - - 3.0062 0.9759 221125_WJC_METTL3_EV_vs_WT_F05.03948.03948.2 0.514 14-Jul K.TLSDATTK.F "sp|Q9NUQ9|CYRIB_HUMAN,tr|A0A1W2PRQ0|A0A1W2PRQ0_HUMAN,tr|A0A087X178|A0A087X178_HUMAN" 3 835.4287 0.83 58303 3948 2 835.430381 418.7216 CYFIP-related Rac1 interactor B OS=Homo sapiens OX=9606 GN=CYRIB PE=1 SV=1 5.5 1397.6 - 1.90E+06 - - - 1.9966 - 1.116 0.164 - 157.5 1 2 0 0.0017 8 0 0 0 1.18E+08 1.42E+08 - - - 0.5828 0.9971 221125_WJC_METTL3_EV_vs_WT_F05.03950.03950.2 0.634 14-Aug K.QLEEQNAR[166.11].L "sp|Q14203|DCTN1_HUMAN,tr|A0A804CDA6|A0A804CDA6_HUMAN,tr|E7EX90|E7EX90_HUMAN,tr|A0A7P0Z4C3|A0A7P0Z4C3_HUMAN,tr|Q6AWB1|Q6AWB1_HUMAN" 5 996.4864 1.89 58305 3950 2 996.483182 499.2505 Dynactin subunit 1 OS=Homo sapiens OX=9606 GN=DCTN1 PE=1 SV=3 4.53 1397.9 - 285171 - - - -3.2213 - 1.798 0.286 - 395.6 1 2 0 -0.0032 8 0 0 0 4.77E+07 2.52E+07 - - - 2.9218 0.9979 221125_WJC_METTL3_EV_vs_WT_F05.03953.03953.2 0.244 12-Jun R.QSPSYGR.H "sp|Q86YZ3|HORN_HUMAN,sp|Q86YZ3|HORN_HUMAN,sp|Q86YZ3|HORN_HUMAN,sp|Q86YZ3|HORN_HUMAN" 4 793.3719 4.49 58306 3953 2 793.370864 397.6932 Hornerin OS=Homo sapiens OX=9606 GN=HRNR PE=1 SV=2 8.75 1398.3 - 3.76E+06 - - - -1.263 - 1.284 0.294 - 148.5 1 2 0 -0.001 7 0 0 0 6.02E+08 1.34E+08 - - - 2.0042 0.9983 221125_WJC_METTL3_EV_vs_WT_F05.03954.03954.2 0.0697 14-Sep R.TQAVVSGR[166.11].R "sp|Q96MU7|YTDC1_HUMAN,tr|J3QR07|J3QR07_HUMAN" 2 826.4536 1.72 58307 3954 2 826.451826 414.2341 YTH domain-containing protein 1 OS=Homo sapiens OX=9606 GN=YTHDC1 PE=1 SV=3 9.41 1398.3 - 2.00E+06 - - - -2.1901 - 1.908 0.233 - 497.4 1 2 0 -0.0018 8 0 0 0 5.39E+07 3.13E+07 - - - 2.7098 0.7721 221125_WJC_METTL3_EV_vs_WT_F05.03961.03961.2 0.819 12-Jul R.SLQDASR.G sp|Q96AQ6|PBIP1_HUMAN 1 775.3824 1.13 58311 3961 2 775.378964 388.6985 Pre-B-cell leukemia transcription factor-interacting protein 1 OS=Homo sapiens OX=9606 GN=PBXIP1 PE=1 SV=1 5.55 1399.1 - 1.97E+06 - - - -4.4713 - 1.257 0.045 - 158.8 1 2 0 -0.0035 7 0 0 0 2.92E+07 2.58E+07 - - - 0.097 0.964 221125_WJC_METTL3_EV_vs_WT_F05.03965.03965.2 3.37 12-May R.SLQDASR[166.11].G sp|Q96AQ6|PBIP1_HUMAN 1 785.3907 1.2 58313 3965 2 785.390699 393.7026 Pre-B-cell leukemia transcription factor-interacting protein 1 OS=Homo sapiens OX=9606 GN=PBXIP1 PE=1 SV=1 5.55 1399.5 - 652678 - - - -0.0025 - 1.167 0.062 - 97.1 3 2 0 0 7 0 0 0 2.91E+07 2.44E+07 - - - -0.2249 0.9993 221125_WJC_METTL3_EV_vs_WT_F05.03969.03969.2 0.165 16-Sep R.SAVPPGADK.K "sp|P46783|RS10_HUMAN,tr|F6U211|F6U211_HUMAN,tr|A0A1W2PQS6|A0A1W2PQS6_HUMAN,tr|A0A2R8YFH6|A0A2R8YFH6_HUMAN,tr|A0A2R8Y7H1|A0A2R8Y7H1_HUMAN,tr|S4R435|S4R435_HUMAN" 6 840.4341 1.32 58316 3969 2 840.432562 421.2243 40S ribosomal protein S10 OS=Homo sapiens OX=9606 GN=RPS10 PE=1 SV=1 5.55 1399.9 - 8.77E+07 - - - -1.8681 - 1.671 0.391 - 267.3 1 2 0 -0.0016 9 0 0 0 3.20E+09 2.43E+09 - - - 3.4138 0.998 221125_WJC_METTL3_EV_vs_WT_F05.03973.03973.2 0.00307 12-Jul K.SYEDATK.L "sp|P27694|RFA1_HUMAN,tr|I3L4R8|I3L4R8_HUMAN" 2 812.3552 1.25 58318 3973 2 812.353236 407.1849 Replication protein A 70 kDa DNA-binding subunit OS=Homo sapiens OX=9606 GN=RPA1 PE=1 SV=2 4.37 1400.4 - 3.05E+06 - - - -2.4337 - 1.376 0.359 - 166.2 1 2 0 -0.002 7 0 0 0 3.61E+08 2.90E+08 - - - 2.7033 0.9989 221125_WJC_METTL3_EV_vs_WT_F05.03983.03983.2 0.0034 12-Jul K.YNADEAR[166.11].S "sp|O14602|IF1AY_HUMAN,sp|P47813|IF1AX_HUMAN,tr|A6NJH9|A6NJH9_HUMAN,tr|X6RAC9|X6RAC9_HUMAN" 4 847.37 0.74 58320 3983 2 847.367722 424.6923 "Eukaryotic translation initiation factor 1A, Y-chromosomal OS=Homo sapiens OX=9606 GN=EIF1AY PE=1 SV=4" 4.37 1401.9 - 5.99E+07 - - - -2.6482 - 1.591 0.4 - 171.8 1 2 0 -0.0022 7 0 0 0 1.24E+09 1.67E+09 - - - 3.4661 0.9991 221125_WJC_METTL3_EV_vs_WT_F05.03990.03990.2 0.00466 14-Jul K.YAPAEGNR.Y "sp|Q96T88|UHRF1_HUMAN,tr|A0A087WWG9|A0A087WWG9_HUMAN,tr|A0A087WTW0|A0A087WTW0_HUMAN,tr|A0A087WVR3|A0A087WVR3_HUMAN" 4 876.409 1.49 58325 3990 2 876.407915 439.2118 E3 ubiquitin-protein ligase UHRF1 OS=Homo sapiens OX=9606 GN=UHRF1 PE=1 SV=1 6 1402.7 - 2.35E+06 - - - -1.2152 - 1.224 0.414 - 151.2 1 2 0 -0.0011 8 0 0 0 8.12E+07 5.45E+07 - - - 2.7081 0.9993 221125_WJC_METTL3_EV_vs_WT_F05.03996.03996.2 0.0147 12-Jul K.YNADEAR.S "sp|O14602|IF1AY_HUMAN,sp|P47813|IF1AX_HUMAN,tr|A6NJH9|A6NJH9_HUMAN,tr|X6RAC9|X6RAC9_HUMAN" 4 837.3617 0.74 58327 3996 2 837.359637 419.6881 "Eukaryotic translation initiation factor 1A, Y-chromosomal OS=Homo sapiens OX=9606 GN=EIF1AY PE=1 SV=4" 4.37 1403.5 - 6.10E+07 - - - -2.4589 - 1.56 0.476 - 181.1 1 2 0 -0.0021 7 0 0 0 1.24E+09 1.67E+09 - - - 3.9651 0.9093 221125_WJC_METTL3_EV_vs_WT_F05.03997.03997.2 0.00194 14-Aug F.MDQAGVDK[136.11].V sp|O43347|MSI1H_HUMAN 1 870.3997 1.21 58328 3997 2 870.397377 436.2071 RNA-binding protein Musashi homolog 1 OS=Homo sapiens OX=9606 GN=MSI1 PE=1 SV=1 4.21 1403.6 - 2.56E+06 - - - -2.6321 - 1.542 0.366 - 166.6 1 1 0 -0.0023 8 0 0 0 1.27E+08 1.05E+08 - - - 3.0497 0.9875 221125_WJC_METTL3_EV_vs_WT_F05.04003.04003.2 0.0591 12-Aug K.IGR[166.11]PGYK[136.11].V "sp|Q15428|SF3A2_HUMAN,tr|K7EMT0|K7EMT0_HUMAN" 2 807.4722 0.77 58331 4003 2 807.471067 404.7434 Splicing factor 3A subunit 2 OS=Homo sapiens OX=9606 GN=SF3A2 PE=1 SV=2 9.99 1404.3 - 1.68E+06 - - - -1.3945 - 1.483 0.059 - 155.6 1 2 0 -0.0011 7 0 0 0 2.58E+07 3.37E+07 - - - 0.725 0.9968 221125_WJC_METTL3_EV_vs_WT_F05.04009.04009.2 0.122 12-Aug K.TTEQDLK.E "sp|Q13148|TADBP_HUMAN,tr|A0A087WX29|A0A087WX29_HUMAN,tr|G3V162|G3V162_HUMAN,tr|A0A087WV68|A0A087WV68_HUMAN,tr|A0A087WYY0|A0A087WYY0_HUMAN,tr|K7EN94|K7EN94_HUMAN,tr|A0A0A0N0M3|A0A0A0N0M3_HUMAN,tr|B1AKP7|B1AKP7_HUMAN,tr|K7EJM5|K7EJM5_HUMAN,tr|A0A087WXQ5|A0A087WXQ5_HUMAN,tr|A0A087X260|A0A087X260_HUMAN" 11 833.4131 0.6 58333 4009 2 833.410343 417.7138 TAR DNA-binding protein 43 OS=Homo sapiens OX=9606 GN=TARDBP PE=1 SV=1 4.37 1405.1 - 4.87E+07 - - - -3.2637 - 1.661 0.298 - 358.6 1 2 0 -0.0027 7 0 0 0 1.24E+09 2.08E+09 - - - 2.849 0.9986 221125_WJC_METTL3_EV_vs_WT_F05.04014.04014.2 0.00333 14-Jul K.ANAEEMTK.Y "sp|Q13547|HDAC1_HUMAN,tr|Q5TEE2|Q5TEE2_HUMAN" 2 892.396 1.7 58336 4014 2 892.393281 447.2053 Histone deacetylase 1 OS=Homo sapiens OX=9606 GN=HDAC1 PE=1 SV=1 4.53 1405.7 - 2.88E+06 - - - -3.0827 - 1.649 0.417 - 200.8 1 2 0 -0.0028 8 0 0 0 2.63E+08 1.55E+08 - - - 3.6286 0.998 221125_WJC_METTL3_EV_vs_WT_F05.04024.04024.2 0.00113 18-Oct R.TTGQAGGGLR.S "sp|O94761|RECQ4_HUMAN,tr|V9GYB6|V9GYB6_HUMAN" 2 916.4726 1.08 58342 4024 2 916.46927 459.2436 ATP-dependent DNA helicase Q4 OS=Homo sapiens OX=9606 GN=RECQL4 PE=1 SV=2 9.41 1406.9 - 1.15E+06 - - - -3.6804 - 2.135 0.345 - 430.4 1 2 0 -0.0034 10 0 0 0 6.01E+07 5.55E+07 - - - 3.7052 0.9994 221125_WJC_METTL3_EV_vs_WT_F05.04035.04035.2 0.00278 16-Sep K.LAQTSDVNK[136.11].M sp|Q68EM7|RHG17_HUMAN 1 982.5175 1.11 58348 4035 2 982.515176 492.266 Rho GTPase-activating protein 17 OS=Homo sapiens OX=9606 GN=ARHGAP17 PE=1 SV=1 5.84 1408.2 - 587714 - - - -2.3399 - 1.877 0.436 - 265.6 1 2 0 -0.0023 9 0 0 0 1.58E+07 1.42E+07 - - - 4.0823 0.9987 221125_WJC_METTL3_EV_vs_WT_F05.04037.04037.2 0.00649 16-Jul R.ATVVESSEK.A sp|P61981|1433G_HUMAN 1 948.4764 1.19 58349 4037 2 948.47417 475.2455 14-3-3 protein gamma OS=Homo sapiens OX=9606 GN=YWHAG PE=1 SV=2 4.53 1408.4 - 3.48E+06 - - - -2.3417 - 1.593 0.368 - 202.8 1 2 0 -0.0022 9 0 0 0 1.78E+08 1.49E+08 - - - 3.1054 0.9997 221125_WJC_METTL3_EV_vs_WT_F05.04038.04038.2 0.0035 16-Sep R.ATVVESSEK[136.11].A sp|P61981|1433G_HUMAN 1 956.4906 1.19 58350 4038 2 956.489343 479.2526 14-3-3 protein gamma OS=Homo sapiens OX=9606 GN=YWHAG PE=1 SV=2 4.53 1408.5 - 3.27E+06 - - - -1.3048 - 1.947 0.409 - 329.5 1 2 0 -0.0012 9 0 0 0 1.78E+08 1.49E+08 - - - 3.9891 0.9557 221125_WJC_METTL3_EV_vs_WT_F05.04041.04041.2 0.000926 14-Sep M.TAQAASYR[166.11].A sp|Q96PK6|RBM14_HUMAN 1 876.4329 1.81 58351 4041 2 876.433805 439.2237 RNA-binding protein 14 OS=Homo sapiens OX=9606 GN=RBM14 PE=1 SV=2 8.41 1408.9 - 1.86E+06 - - - 1.0326 - 1.493 0.357 - 391 1 1 0 0.0009 8 0 0 0 6.50E+07 3.59E+07 - - - 2.8863 0.994 221125_WJC_METTL3_EV_vs_WT_F05.04044.04044.2 0.00886 14-Aug K.VSNSGITR.V sp|P50991|TCPD_HUMAN 1 832.4403 0.31 58352 4044 2 832.438552 417.2274 T-complex protein 1 subunit delta OS=Homo sapiens OX=9606 GN=CCT4 PE=1 SV=4 9.72 1409.2 - 2.32E+07 - - - -2.0758 - 1.651 0.138 - 199.3 1 2 0 -0.0017 8 0 0 0 1.06E+09 3.39E+09 - - - 1.5719 0.943 221125_WJC_METTL3_EV_vs_WT_F05.04046.04046.2 1.91 14-Jun K.QPASQLQK.Q "sp|Q16891|MIC60_HUMAN,tr|B9A067|B9A067_HUMAN,tr|A0A087WYS0|A0A087WYS0_HUMAN,tr|D6RAW4|D6RAW4_HUMAN,tr|C9J406|C9J406_HUMAN,tr|H7C463|H7C463_HUMAN" 6 898.4872 1.01 58354 4046 2 898.484952 450.2509 MICOS complex subunit MIC60 OS=Homo sapiens OX=9606 GN=IMMT PE=1 SV=1 8.75 1409.3 - 2.92E+06 - - - -2.5354 - 1.146 0.102 - 163.7 1 2 0 -0.0023 8 0 0 0 8.90E+07 8.85E+07 - - - 0.2047 0.9776 221125_WJC_METTL3_EV_vs_WT_F05.04063.04063.2 0.204 14-Jun R.VIAHTQMR[166.11].L "sp|P39023|RL3_HUMAN,tr|G5E9G0|G5E9G0_HUMAN,tr|H7C3M2|H7C3M2_HUMAN,tr|B5MCW2|B5MCW2_HUMAN,tr|H7C422|H7C422_HUMAN" 5 964.5152 0.62 58363 4063 2 964.513076 483.2649 60S ribosomal protein L3 OS=Homo sapiens OX=9606 GN=RPL3 PE=1 SV=2 9.73 1411.5 - 1.13E+06 - - - -2.1918 - 1.116 0.177 - 139.1 1 2 0 -0.0021 8 0 0 0 1.97E+07 3.18E+07 - - - 0.6787 0.9828 221125_WJC_METTL3_EV_vs_WT_F05.04066.04066.2 0.765 14-Jul K.LGETDEEK[136.11].L "sp|Q9Y3D9|RT23_HUMAN,tr|J3QLR8|J3QLR8_HUMAN" 2 927.4277 3.04 58364 4066 2 927.425216 464.7211 "28S ribosomal protein S23, mitochondrial OS=Homo sapiens OX=9606 GN=MRPS23 PE=1 SV=2" 4 1411.9 - 1.20E+06 - - - -2.6309 - 1.325 0.162 - 91.1 1 2 0 -0.0024 8 0 0 0 7.17E+07 2.36E+07 - - - 1.0855 0.9641 221125_WJC_METTL3_EV_vs_WT_F05.04068.04068.2 0.0384 14-Aug R.ELC[160.03]SGPSK[136.11].L "sp|P29372|3MG_HUMAN,tr|A2IDA3|A2IDA3_HUMAN" 2 884.4153 1.4 58366 4068 2 884.413164 443.2149 DNA-3-methyladenine glycosylase OS=Homo sapiens OX=9606 GN=MPG PE=1 SV=3 6.09 1412.1 - 685432 - - - -2.4355 - 1.381 0.062 - 235 1 2 0 -0.0022 8 0 0 0 7.72E+07 5.51E+07 - - - 0.4718 0.9996 221125_WJC_METTL3_EV_vs_WT_F05.04071.04071.2 0.000914 14-Sep R.FEDC[160.03]SSAK.T sp|O43143|DHX15_HUMAN 1 942.3753 0.66 58367 4071 2 942.373402 472.1949 Pre-mRNA-splicing factor ATP-dependent RNA helicase DHX15 OS=Homo sapiens OX=9606 GN=DHX15 PE=1 SV=2 4.37 1412.5 - 1.01E+06 - - - -2.0109 - 1.449 0.533 - 172.8 1 2 0 -0.0019 8 0 0 0 4.96E+07 7.57E+07 - - - 4.0957 0.9978 221125_WJC_METTL3_EV_vs_WT_F05.04075.04075.2 0.00251 14-Aug R.ELC[160.03]DSEGK.S sp|P0C7T5|ATX1L_HUMAN 1 936.3859 1.74 58369 4075 2 936.383066 469.2002 Ataxin-1-like OS=Homo sapiens OX=9606 GN=ATXN1L PE=1 SV=1 4.14 1412.9 - 1.43E+06 - - - -2.9859 - 1.28 0.441 - 296.6 1 2 0 -0.0028 8 0 0 0 4.54E+07 2.61E+07 - - - 3.0419 0.9859 221125_WJC_METTL3_EV_vs_WT_F05.04079.04079.2 0.184 12-Jun R.NVYSSSR.Y "sp|O75494|SRS10_HUMAN,tr|Q5JRI1|Q5JRI1_HUMAN" 2 811.3824 1.28 58372 4079 2 811.380457 406.6985 Serine\arginine-rich splicing factor 10 OS=Homo sapiens OX=9606 GN=SRSF10 PE=1 SV=1 8.75 1413.3 - 9.66E+06 - - - -2.4329 - 1.076 0.251 - 120.6 1 2 0 -0.002 7 0 0 0 2.97E+08 2.33E+08 - - - 1.1264 0.9964 221125_WJC_METTL3_EV_vs_WT_F05.04083.04083.2 0.0145 14-Aug R.FEDC[160.03]SSAK[136.11].T sp|O43143|DHX15_HUMAN 1 950.3895 0.7 58373 4083 2 950.385751 476.202 Pre-mRNA-splicing factor ATP-dependent RNA helicase DHX15 OS=Homo sapiens OX=9606 GN=DHX15 PE=1 SV=2 4.37 1413.9 - 2.46E+06 - - - -3.9415 - 1.44 0.421 - 153.2 1 2 0 -0.0037 8 0 0 0 4.96E+07 7.11E+07 - - - 3.2491 0.9994 221125_WJC_METTL3_EV_vs_WT_F05.04092.04092.2 0.032 16-Aug K.ADGEEDEVK.A "sp|Q15020|SART3_HUMAN,tr|A0A494C0L2|A0A494C0L2_HUMAN,tr|F8W667|F8W667_HUMAN,tr|A0A499FI31|A0A499FI31_HUMAN" 4 990.4142 4.22 58377 4092 2 990.412718 496.2144 Squamous cell carcinoma antigen recognized by T-cells 3 OS=Homo sapiens OX=9606 GN=SART3 PE=1 SV=1 3.83 1415.1 - 507441 - - - -1.4812 - 1.517 0.42 - 226.2 1 2 0 -0.0015 9 0 0 0 5.88E+07 1.39E+07 - - - 3.3483 0.7673 221125_WJC_METTL3_EV_vs_WT_F05.04093.04093.2 4.56 12-Jun R.SLETENR[166.11].R "sp|P05783|K1C18_HUMAN,tr|F8VZY9|F8VZY9_HUMAN" 2 857.4118 1.84 58378 4093 2 857.409334 429.7132 "Keratin, type I cytoskeletal 18 OS=Homo sapiens OX=9606 GN=KRT18 PE=1 SV=2" 4.53 1415.2 - 3.11E+06 - - - -2.9111 - 1.034 0.03 - 101 1 2 0 -0.0025 7 0 0 0 2.46E+08 1.34E+08 - - - -0.6323 0.9879 221125_WJC_METTL3_EV_vs_WT_F05.04096.04096.2 0.0511 12-Jun R.LIEDKPR.T "sp|Q13247|SRSF6_HUMAN,tr|A0A590UK80|A0A590UK80_HUMAN,tr|A0A590UJK4|A0A590UJK4_HUMAN,tr|A0A590UJP7|A0A590UJP7_HUMAN,tr|A0A590UK01|A0A590UK01_HUMAN" 5 869.4971 1.19 58379 4096 2 869.495544 435.7558 Serine\arginine-rich splicing factor 6 OS=Homo sapiens OX=9606 GN=SRSF6 PE=1 SV=2 6.07 1415.6 - 2.79E+06 - - - -1.7516 - 1.254 0.154 - 148.3 1 2 0 -0.0015 7 0 0 0 5.87E+07 4.92E+07 - - - 0.8951 0.9969 221125_WJC_METTL3_EV_vs_WT_F05.04103.04103.2 0.0134 16-Aug R.SAVPPGADK[136.11].K "sp|P46783|RS10_HUMAN,tr|F6U211|F6U211_HUMAN,tr|A0A1W2PQS6|A0A1W2PQS6_HUMAN,tr|A0A2R8YFH6|A0A2R8YFH6_HUMAN,tr|A0A2R8Y7H1|A0A2R8Y7H1_HUMAN,tr|S4R435|S4R435_HUMAN" 6 848.4483 2.22 58382 4103 2 848.446589 425.2314 40S ribosomal protein S10 OS=Homo sapiens OX=9606 GN=RPS10 PE=1 SV=1 5.55 1416.5 - 1.35E+07 - - - -2.0543 - 1.367 0.291 - 191 1 2 0 -0.0017 9 0 0 0 7.23E+09 3.26E+09 - - - 2.0942 0.969 221125_WJC_METTL3_EV_vs_WT_F05.04107.04107.2 0.000882 16-Oct K.TPEASPEPK[136.11].D "sp|Q99460|PSMD1_HUMAN,tr|A0A7I2V4X0|A0A7I2V4X0_HUMAN,tr|A0A7I2V2K8|A0A7I2V2K8_HUMAN,tr|A0A7I2YQY1|A0A7I2YQY1_HUMAN,tr|A0A7I2V523|A0A7I2V523_HUMAN,tr|A0A7I2V641|A0A7I2V641_HUMAN,tr|A0A7I2V491|A0A7I2V491_HUMAN,tr|A0A7I2YQI9|A0A7I2YQI9_HUMAN,tr|A0A7I2V262|A0A7I2V262_HUMAN,tr|A0A087WW66|A0A087WW66_HUMAN,tr|A0A7P0MW50|A0A7P0MW50_HUMAN,tr|A0A7I2V4A5|A0A7I2V4A5_HUMAN,tr|A0A7I2V5C8|A0A7I2V5C8_HUMAN,tr|A0A7I2V479|A0A7I2V479_HUMAN" 14 962.48 0.98 58386 4107 2 962.472576 482.2473 26S proteasome non-ATPase regulatory subunit 1 OS=Homo sapiens OX=9606 GN=PSMD1 PE=1 SV=2 4.53 1416.9 - 607421 - - - -7.7404 - 1.694 0.421 - 297.2 1 2 0 -0.0075 9 0 0 0 7.60E+07 7.76E+07 - - - 3.6731 0.9994 221125_WJC_METTL3_EV_vs_WT_F05.04110.04110.2 0.00211 16-Aug R.QAETEAEVK[136.11].K sp|Q96RS0|TGS1_HUMAN 1 1011.4964 1.35 58387 4110 2 1011.495394 506.7555 Trimethylguanosine synthase OS=Homo sapiens OX=9606 GN=TGS1 PE=1 SV=3 4.25 1417.3 - 783535 - - - -0.9995 - 1.581 0.364 - 338.9 1 2 0 -0.001 9 0 0 0 2.77E+07 2.05E+07 - - - 3.0544 0.998 221125_WJC_METTL3_EV_vs_WT_F05.04119.04119.2 0.288 12-Aug R.ESGVPDR.F sp|P06312|KV401_HUMAN 1 758.3559 999 58390 4119 2 758.354681 380.1852 Immunoglobulin kappa variable 4-1 OS=Homo sapiens OX=9606 GN=IGKV4-1 PE=1 SV=1 4.37 1418.5 - 1.84E+06 - - - -1.5837 - 1.344 0.299 - 297.3 1 2 0 -0.0012 7 0 0 0 6.64E+07 0.00E+00 - - - 2.1858 0.9994 221125_WJC_METTL3_EV_vs_WT_F05.04120.04120.2 0.00172 18-Sep K.LEGQAQAEAK.A "sp|O00541|PESC_HUMAN,tr|B3KXD6|B3KXD6_HUMAN,tr|B5MCF9|B5MCF9_HUMAN,tr|H7BYY8|H7BYY8_HUMAN" 4 1043.5247 0.8 58391 4120 2 1043.523515 522.7696 Pescadillo homolog OS=Homo sapiens OX=9606 GN=PES1 PE=1 SV=1 4.53 1418.6 - 332080 - - - -1.172 - 1.695 0.346 - 192.2 1 2 0 -0.0012 10 0 0 0 1.19E+07 1.49E+07 - - - 3.0691 0.9996 221125_WJC_METTL3_EV_vs_WT_F05.04125.04125.2 0.000223 16-Dec K.TPEASPEPK.D "sp|Q99460|PSMD1_HUMAN,tr|A0A7I2V4X0|A0A7I2V4X0_HUMAN,tr|A0A7I2V2K8|A0A7I2V2K8_HUMAN,tr|A0A7I2YQY1|A0A7I2YQY1_HUMAN,tr|A0A7I2V523|A0A7I2V523_HUMAN,tr|A0A7I2V641|A0A7I2V641_HUMAN,tr|A0A7I2V491|A0A7I2V491_HUMAN,tr|A0A7I2YQI9|A0A7I2YQI9_HUMAN,tr|A0A7I2V262|A0A7I2V262_HUMAN,tr|A0A087WW66|A0A087WW66_HUMAN,tr|A0A7P0MW50|A0A7P0MW50_HUMAN,tr|A0A7I2V4A5|A0A7I2V4A5_HUMAN,tr|A0A7I2V5C8|A0A7I2V5C8_HUMAN,tr|A0A7I2V479|A0A7I2V479_HUMAN" 14 954.4658 0.96 58394 4125 2 954.463763 478.2402 26S proteasome non-ATPase regulatory subunit 1 OS=Homo sapiens OX=9606 GN=PSMD1 PE=1 SV=2 4.53 1419.2 - 1.01E+06 - - - -2.1614 - 2.335 0.377 - 592.1 1 2 0 -0.0021 9 0 0 0 7.41E+07 7.76E+07 - - - 4.2782 0.8819 221125_WJC_METTL3_EV_vs_WT_F05.04126.04126.2 5.77 16-Jul R.VQGTPVASK.L "sp|Q9UNQ2|DIM1_HUMAN,tr|A0A494C0G7|A0A494C0G7_HUMAN,tr|B4DRY2|B4DRY2_HUMAN,tr|A0A0C4DGB1|A0A0C4DGB1_HUMAN,tr|A0A7P0T9J1|A0A7P0T9J1_HUMAN,tr|A0A7P0Z4I0|A0A7P0Z4I0_HUMAN,tr|A0A7P0T9Y7|A0A7P0T9Y7_HUMAN,tr|D6RCL3|D6RCL3_HUMAN" 8 885.492 0.77 58395 4126 2 885.490075 443.7533 Probable dimethyladenosine transferase OS=Homo sapiens OX=9606 GN=DIMT1 PE=1 SV=1 8.72 1419.3 - 601703 - - - -2.1536 - 1.195 0.051 - 89.7 8 2 0 -0.0019 9 0 0 0 2.23E+07 2.90E+07 - - - -0.4709 0.9887 221125_WJC_METTL3_EV_vs_WT_F05.04137.04137.2 4.23 16-Jul K.GLQTSQDAR[166.11].F "sp|P27797|CALR_HUMAN,tr|A0A7P0T861|A0A7P0T861_HUMAN,tr|K7EL50|K7EL50_HUMAN" 3 984.4864 0.65 58401 4137 2 984.484311 493.2505 Calreticulin OS=Homo sapiens OX=9606 GN=CALR PE=1 SV=1 5.84 1420.7 - 476639 - - - -2.1138 - 1.426 0.143 - 165 1 2 0 -0.0021 9 0 0 0 1.07E+07 1.64E+07 - - - 1.1232 0.9169 221125_WJC_METTL3_EV_vs_WT_F05.04140.04140.2 3.67 14-Jun K.ILSEEGR[166.11]R[166.11].Q "sp|Q13303|KCAB2_HUMAN,tr|A0A590UJJ4|A0A590UJJ4_HUMAN,tr|A0A5F9UN28|A0A5F9UN28_HUMAN,tr|A0A590UJB6|A0A590UJB6_HUMAN" 4 978.5361 1.52 58403 4140 2 978.53464 490.2753 Voltage-gated potassium channel subunit beta-2 OS=Homo sapiens OX=9606 GN=KCNAB2 PE=1 SV=2 6.14 1421.1 - 814037 - - - -1.5257 - 1.057 0.059 - 80.3 2 2 0 -0.0015 8 0 0 0 2.67E+07 1.75E+07 - - - -0.491 0.8472 221125_WJC_METTL3_EV_vs_WT_F05.04141.04141.2 2.09 14-Jun R.SSPDGGLK.G sp|P48634|PRC2A_HUMAN 1 759.3763 0.09 58404 4141 2 759.378761 380.6954 Protein PRRC2A OS=Homo sapiens OX=9606 GN=PRRC2A PE=1 SV=3 5.55 1421.1 - 1.77E+06 - - - 3.2632 - 1.074 0.137 - 148.3 8 2 0 0.0025 8 0 0 0 1.09E+08 1.20E+09 - - - -0.136 0.9938 221125_WJC_METTL3_EV_vs_WT_F05.04146.04146.2 0.567 12-Aug R.SNQELER.L "sp|Q15643|TRIPB_HUMAN,tr|H0YJ97|H0YJ97_HUMAN" 2 874.4145 1.25 58406 4146 2 874.412756 438.2145 Thyroid receptor-interacting protein 11 OS=Homo sapiens OX=9606 GN=TRIP11 PE=1 SV=3 4.53 1421.7 - 2.39E+06 - - - -1.9476 - 1.456 0.17 - 372.8 1 2 0 -0.0017 7 0 0 0 1.12E+08 8.96E+07 - - - 1.4865 0.9978 221125_WJC_METTL3_EV_vs_WT_F05.04147.04147.2 0.0296 14-Jul R.SNVVSPTK.N "sp|Q71RC2|LARP4_HUMAN,tr|X6RLN4|X6RLN4_HUMAN" 2 830.4498 3.98 58407 4147 2 830.448053 416.2322 La-related protein 4 OS=Homo sapiens OX=9606 GN=LARP4 PE=1 SV=3 8.47 1421.8 - 1.01E+06 - - - -2.082 - 1.346 0.334 - 239.7 1 2 0 -0.0017 8 0 0 0 1.47E+08 3.69E+07 - - - 2.4035 0.9379 221125_WJC_METTL3_EV_vs_WT_F05.04160.04160.2 3.08 16-Jul R.VPSHAVVAR.S "sp|P02788|TRFL_HUMAN,tr|E7EQB2|E7EQB2_HUMAN,tr|E7ER44|E7ER44_HUMAN" 3 934.5348 131.93 58411 4160 2 934.53378 468.2747 Lactotransferrin OS=Homo sapiens OX=9606 GN=LTF PE=1 SV=6 9.73 1423.6 - 316193 - - - -1.1439 - 1.077 0.043 - 156.3 1 2 0 -0.0011 9 0 0 0 3.78E+07 2.86E+05 - - - -0.4271 0.9993 221125_WJC_METTL3_EV_vs_WT_F05.04165.04165.2 0.00503 12-Aug R.TIAPC[160.03]QK.A "sp|P38646|GRP75_HUMAN,tr|H0Y8K0|H0Y8K0_HUMAN,tr|A0A7I2V2S7|A0A7I2V2S7_HUMAN,tr|A0A7I2V2G2|A0A7I2V2G2_HUMAN,tr|A0A7I2V3F7|A0A7I2V3F7_HUMAN,tr|A0A7I2YQB2|A0A7I2YQB2_HUMAN,tr|D6RCD7|D6RCD7_HUMAN" 7 816.4164 0.32 58414 4165 2 816.416125 409.2155 "Stress-70 protein, mitochondrial OS=Homo sapiens OX=9606 GN=HSPA9 PE=1 SV=2" 7.89 1424.1 - 3.17E+06 - - - -0.305 - 1.503 0.32 - 207.1 1 2 0 -0.0002 7 0 0 0 5.70E+08 1.76E+09 - - - 2.6955 0.9971 221125_WJC_METTL3_EV_vs_WT_F05.04169.04169.2 0.208 14-Jul R.EVEPGEDR[166.11].T sp|Q147X3|NAA30_HUMAN 1 939.4173 0.49 58416 4169 2 939.415732 470.7159 N-alpha-acetyltransferase 30 OS=Homo sapiens OX=9606 GN=NAA30 PE=1 SV=1 4 1424.7 - 278027 - - - -1.6798 - 1.293 0.288 - 243.8 1 2 0 -0.0016 8 0 0 0 3.07E+06 6.28E+06 - - - 1.9427 0.9579 221125_WJC_METTL3_EV_vs_WT_F05.04170.04170.2 0.00926 16-Oct M.AVAHALTEK[136.11].S "sp|P49368|TCPG_HUMAN,tr|B4DUR8|B4DUR8_HUMAN" 2 946.5327 0.23 58417 4170 2 946.531842 474.2736 T-complex protein 1 subunit gamma OS=Homo sapiens OX=9606 GN=CCT3 PE=1 SV=4 6.79 1424.8 - 513203 - - - -0.9392 - 1.736 0.293 - 358.5 1 1 0 -0.0009 9 0 0 0 5.92E+06 2.59E+07 - - - 2.8006 0.9949 221125_WJC_METTL3_EV_vs_WT_F05.04174.04174.2 0.0348 16-Jul K.IIENGENEK[136.11].T "sp|Q9Y3B8|ORN_HUMAN,tr|H0YGR4|H0YGR4_HUMAN,tr|F5GYG5|F5GYG5_HUMAN,tr|H0YG54|H0YG54_HUMAN" 4 1052.523 1.87 58419 4174 2 1052.519244 527.2688 "Oligoribonuclease, mitochondrial OS=Homo sapiens OX=9606 GN=REXO2 PE=1 SV=3" 4.25 1425.3 - 261692 - - - -3.5249 - 1.683 0.277 - 93.7 1 2 0 -0.0037 9 0 0 0 1.45E+07 7.77E+06 - - - 2.5918 0.9997 221125_WJC_METTL3_EV_vs_WT_F05.04186.04186.2 0.0112 16-Oct K.GTGASGSFK.L "sp|P16401|H15_HUMAN,sp|P10412|H14_HUMAN,sp|Q02539|H11_HUMAN,sp|P22492|H1T_HUMAN,sp|P16403|H12_HUMAN,sp|P16402|H13_HUMAN" 6 810.3872 0.7 58423 4186 2 810.386401 406.2009 Histone H1.5 OS=Homo sapiens OX=9606 GN=H1-5 PE=1 SV=3 8.75 1427 - 7.35E+06 - - - -0.9637 - 1.844 0.402 - 391.4 1 2 0 -0.0008 9 0 0 0 8.32E+08 1.19E+09 - - - 3.7803 0.9994 221125_WJC_METTL3_EV_vs_WT_F05.04197.04197.2 0.00042 16-Aug K.GTGASGSFK[136.11].L "sp|P16401|H15_HUMAN,sp|P10412|H14_HUMAN,sp|Q02539|H11_HUMAN,sp|P22492|H1T_HUMAN,sp|P16403|H12_HUMAN,sp|P16402|H13_HUMAN" 6 818.4014 0.7 58428 4197 2 818.399739 410.208 Histone H1.5 OS=Homo sapiens OX=9606 GN=H1-5 PE=1 SV=3 8.75 1428.4 - 3.42E+07 - - - -2.0076 - 1.607 0.443 - 188 1 2 0 -0.0016 9 0 0 0 8.27E+08 1.19E+09 - - - 3.6849 0.917 221125_WJC_METTL3_EV_vs_WT_F05.04200.04200.2 6.65 12-Jun R.APQC[160.03]LGK[136.11].F "sp|Q00839|HNRPU_HUMAN,tr|A0A1W2PQL0|A0A1W2PQL0_HUMAN,tr|A0A1W2PPE9|A0A1W2PPE9_HUMAN,tr|A0A1W2PPL4|A0A1W2PPL4_HUMAN,tr|A0A1W2PQ74|A0A1W2PQ74_HUMAN,tr|Q5RI18|Q5RI18_HUMAN,tr|A0A1W2PP35|A0A1W2PP35_HUMAN,tr|A0A1W2PPS1|A0A1W2PPS1_HUMAN,tr|A0A1W2PRZ7|A0A1W2PRZ7_HUMAN,tr|A0A1W2PPH7|A0A1W2PPH7_HUMAN,tr|A0A1W2PQD4|A0A1W2PQD4_HUMAN,tr|A0A1W2PP34|A0A1W2PP34_HUMAN,tr|A0A1X7SBS1|A0A1X7SBS1_HUMAN" 13 780.4044 1.22 58429 4200 2 780.402166 391.2095 Heterogeneous nuclear ribonucleoprotein U OS=Homo sapiens OX=9606 GN=HNRNPU PE=1 SV=6 8.27 1428.7 - 1.05E+07 - - - -2.8101 - 1.098 0.1 - 120.4 1 2 0 -0.0022 7 0 0 0 6.29E+08 5.14E+08 - - - 0.0751 0.9951 221125_WJC_METTL3_EV_vs_WT_F05.04205.04205.2 0.0939 14-Jul K.SAPDQEVR.L sp|P36405|ARL3_HUMAN 1 900.4301 2.57 58431 4205 2 900.430355 451.2223 ADP-ribosylation factor-like protein 3 OS=Homo sapiens OX=9606 GN=ARL3 PE=1 SV=2 4.37 1429.4 - 898690 - - - 0.2721 - 1.237 0.197 - 176.1 1 2 0 0.0002 8 0 0 0 5.74E+07 2.24E+07 - - - 1.1374 0.997 221125_WJC_METTL3_EV_vs_WT_F05.04206.04206.2 9.84E-05 22-Oct R.AAPGAAGNGAVR.G sp|Q96GI7|FA89A_HUMAN 1 1010.5257 1.48 58432 4206 2 1010.529599 506.2701 Protein FAM89A OS=Homo sapiens OX=9606 GN=FAM89A PE=1 SV=1 9.79 1429.5 - 304018 - - - 3.8178 - 1.913 0.356 - 274.6 1 2 0 0.0039 12 0 0 0 3.41E+07 2.31E+07 - - - 3.376 0.9495 221125_WJC_METTL3_EV_vs_WT_F05.04210.04210.2 6.44 12-Jun R.APQC[160.03]LGK.F "sp|Q00839|HNRPU_HUMAN,tr|A0A1W2PQL0|A0A1W2PQL0_HUMAN,tr|A0A1W2PPE9|A0A1W2PPE9_HUMAN,tr|A0A1W2PPL4|A0A1W2PPL4_HUMAN,tr|A0A1W2PQ74|A0A1W2PQ74_HUMAN,tr|Q5RI18|Q5RI18_HUMAN,tr|A0A1W2PP35|A0A1W2PP35_HUMAN,tr|A0A1W2PPS1|A0A1W2PPS1_HUMAN,tr|A0A1W2PRZ7|A0A1W2PRZ7_HUMAN,tr|A0A1W2PPH7|A0A1W2PPH7_HUMAN,tr|A0A1W2PQD4|A0A1W2PQD4_HUMAN,tr|A0A1W2PP34|A0A1W2PP34_HUMAN,tr|A0A1X7SBS1|A0A1X7SBS1_HUMAN" 13 772.3902 1.3 58434 4210 2 772.388707 387.2024 Heterogeneous nuclear ribonucleoprotein U OS=Homo sapiens OX=9606 GN=HNRNPU PE=1 SV=6 8.27 1430 - 9.66E+06 - - - -1.8799 - 1.113 0.082 - 146.2 1 2 0 -0.0015 7 0 0 0 6.66E+08 5.14E+08 - - - -0.0146 0.9977 221125_WJC_METTL3_EV_vs_WT_F05.04213.04213.2 0.173 14-Jun K.IQNDAGVR[166.11].L "sp|Q96I24|FUBP3_HUMAN,sp|Q92945|FUBP2_HUMAN,sp|Q96AE4|FUBP1_HUMAN,tr|M0R0I5|M0R0I5_HUMAN,tr|E9PEB5|E9PEB5_HUMAN,tr|M0R0C6|M0R0C6_HUMAN,tr|A0A087WTP3|A0A087WTP3_HUMAN" 7 881.4594 1.72 58437 4213 2 881.458747 441.737 Far upstream element-binding protein 3 OS=Homo sapiens OX=9606 GN=FUBP3 PE=1 SV=2 5.84 1430.2 - 1.74E+06 - - - -0.7964 - 1.499 0.221 - 102.3 2 2 0 -0.0007 8 0 0 0 1.23E+09 7.14E+08 - - - 1.7595 0.9971 221125_WJC_METTL3_EV_vs_WT_F05.04215.04215.2 0.0591 16-Jul R.SAVPPGADK.K "sp|P46783|RS10_HUMAN,tr|F6U211|F6U211_HUMAN,tr|A0A1W2PQS6|A0A1W2PQS6_HUMAN,tr|A0A2R8YFH6|A0A2R8YFH6_HUMAN,tr|A0A2R8Y7H1|A0A2R8Y7H1_HUMAN,tr|S4R435|S4R435_HUMAN" 6 840.4341 1.3 58438 4215 2 840.433377 421.2243 40S ribosomal protein S10 OS=Homo sapiens OX=9606 GN=RPS10 PE=1 SV=1 5.55 1430.4 - 1.61E+07 - - - -0.8983 - 1.272 0.253 - 167.9 1 2 0 -0.0008 9 0 0 0 1.31E+09 1.01E+09 - - - 1.6055 0.9943 221125_WJC_METTL3_EV_vs_WT_F05.04219.04219.2 0.204 16-Aug K.SLQEANAEK[136.11].V sp|Q14126|DSG2_HUMAN 1 996.4967 1.34 58441 4219 2 996.494677 499.2556 Desmoglein-2 OS=Homo sapiens OX=9606 GN=DSG2 PE=1 SV=2 4.53 1430.9 - 223863 - - - -2.0692 - 1.42 0.211 - 180.4 1 2 0 -0.0021 9 0 0 0 3.56E+07 2.66E+07 - - - 1.6133 0.9996 221125_WJC_METTL3_EV_vs_WT_F05.04226.04226.2 0.00626 22-Nov R.AAPGAAGNGAVR[166.11].G sp|Q96GI7|FA89A_HUMAN 1 1020.534 1.52 58444 4226 2 1020.532674 511.2743 Protein FAM89A OS=Homo sapiens OX=9606 GN=FAM89A PE=1 SV=1 9.79 1431.7 - 475985 - - - -1.3101 - 1.922 0.386 - 374.9 1 2 0 -0.0013 12 0 0 0 3.51E+07 2.31E+07 - - - 3.6107 0.8265 221125_WJC_METTL3_EV_vs_WT_F05.04227.04227.2 7.23 16-May R.LPAR[166.11]PAPSR[166.11].G sp|Q9H8W2|CF155_HUMAN 1 983.5779 0.71 58445 4227 2 983.576422 492.7962 Putative uncharacterized protein encoded by LINC00472 OS=Homo sapiens OX=9606 GN=LINC00472 PE=5 SV=2 12 1431.9 - 466863 - - - -1.5413 - 1.03 0.001 - 47.7 2 2 0 -0.0015 9 0 0 0 8.82E+06 1.25E+07 - - - -1.001 0.9774 221125_WJC_METTL3_EV_vs_WT_F05.04230.04230.2 2.78 12-Jun R.LSNEVSR.L "sp|Q15643|TRIPB_HUMAN,tr|G3V4R7|G3V4R7_HUMAN" 2 803.4137 1.13 58446 4230 2 803.412477 402.7141 Thyroid receptor-interacting protein 11 OS=Homo sapiens OX=9606 GN=TRIP11 PE=1 SV=3 6 1432.3 - 2.70E+06 - - - -1.5608 - 1.275 0.107 - 127.6 3 2 0 -0.0013 7 0 0 0 3.90E+08 3.45E+08 - - - 0.3876 0.9929 221125_WJC_METTL3_EV_vs_WT_F05.04233.04233.2 0.178 14-Jun K.YLPHSAGR.Y "sp|P46782|RS5_HUMAN,tr|M0R0F0|M0R0F0_HUMAN,tr|M0R0R2|M0R0R2_HUMAN" 3 899.4614 0.95 58447 4233 2 899.460292 450.738 40S ribosomal protein S5 OS=Homo sapiens OX=9606 GN=RPS5 PE=1 SV=4 8.75 1432.7 - 1.11E+06 - - - -1.1763 - 1.019 0.263 - 164.9 1 2 0 -0.0011 8 0 0 0 1.03E+09 1.08E+09 - - - 1.04 0.8949 221125_WJC_METTL3_EV_vs_WT_F05.04243.04243.2 2.66 14-Jun K.YLPHSAGR[166.11].Y "sp|P46782|RS5_HUMAN,tr|M0R0F0|M0R0F0_HUMAN,tr|M0R0R2|M0R0R2_HUMAN" 3 909.4696 0.95 58451 4243 2 909.467583 455.7421 40S ribosomal protein S5 OS=Homo sapiens OX=9606 GN=RPS5 PE=1 SV=4 8.75 1434 - 6.76E+06 - - - -2.2398 - 0.974 0.093 - 143.9 1 2 0 -0.002 8 0 0 0 1.03E+09 1.09E+09 - - - -0.3522 0.9991 221125_WJC_METTL3_EV_vs_WT_F05.04245.04245.2 0.0251 14-Oct K.C[160.03]IAC[160.03]QAAK.L sp|P49790|NU153_HUMAN 1 920.4208 11.51 58452 4245 2 920.418592 461.2177 Nuclear pore complex protein Nup153 OS=Homo sapiens OX=9606 GN=NUP153 PE=1 SV=2 8.06 1434.2 - 6.42E+06 - - - -2.4076 - 1.778 0.37 - 357.5 1 2 0 -0.0022 8 0 0 0 1.41E+09 1.22E+08 - - - 3.5088 0.998 221125_WJC_METTL3_EV_vs_WT_F05.04246.04246.2 0.00146 14-Aug K.LTTC[160.03]TGC[160.03]R[166.11].T sp|Q9UBW7|ZMYM2_HUMAN 1 977.4298 0.62 58453 4246 2 977.426747 489.7222 Zinc finger MYM-type protein 2 OS=Homo sapiens OX=9606 GN=ZMYM2 PE=1 SV=1 8.07 1434.3 - 404978 - - - -3.1296 - 1.378 0.438 - 184.1 1 2 0 -0.0031 8 0 0 0 4.60E+06 7.42E+06 - - - 3.2421 0.9655 221125_WJC_METTL3_EV_vs_WT_F05.04248.04248.2 0.0579 16-Jul K.LTPNAGSDR[166.11].S sp|P49792|RBP2_HUMAN 1 939.4649 0.16 58455 4248 2 939.469749 470.7397 E3 SUMO-protein ligase RanBP2 OS=Homo sapiens OX=9606 GN=RANBP2 PE=1 SV=2 5.84 1434.6 - 772627 - - - 5.1306 - 1.544 0.224 - 142 1 2 0 0.0048 9 0 0 0 7.07E+06 4.33E+07 - - - 1.9506 0.9979 221125_WJC_METTL3_EV_vs_WT_F05.04249.04249.2 0.0835 14-Sep K.LAEEESC[160.03]R[166.11].E "sp|Q92896|GSLG1_HUMAN,tr|H3BRD8|H3BRD8_HUMAN,tr|H3BQU9|H3BQU9_HUMAN,tr|H3BM42|H3BM42_HUMAN" 4 1002.4316 1.44 58456 4249 2 1002.431368 502.2231 Golgi apparatus protein 1 OS=Homo sapiens OX=9606 GN=GLG1 PE=1 SV=2 4.25 1434.7 - 247039 - - - -0.2115 - 1.529 0.195 - 349.7 1 2 0 -0.0002 8 0 0 0 1.33E+07 9.25E+06 - - - 1.7618 0.993 221125_WJC_METTL3_EV_vs_WT_F05.04258.04258.2 0.104 16-Jun K.ITEAPASEK[136.11].E "sp|P82970|HMGN5_HUMAN,tr|Q5JSK9|Q5JSK9_HUMAN,tr|Q5JSK8|Q5JSK8_HUMAN,tr|Q5JSK6|Q5JSK6_HUMAN,tr|Q5JSL0|Q5JSL0_HUMAN" 5 952.4957 0.76 58461 4258 2 952.496367 477.2551 High mobility group nucleosome-binding domain-containing protein 5 OS=Homo sapiens OX=9606 GN=HMGN5 PE=1 SV=1 4.53 1435.8 - 406038 - - - 0.7255 - 1.352 0.144 - 87.8 1 2 0 0.0007 9 0 0 0 2.53E+07 3.35E+07 - - - 0.9769 0.9994 221125_WJC_METTL3_EV_vs_WT_F05.04260.04260.2 0.0558 18-Nov R.LAQEEESEAK[136.11].R "sp|O00541|PESC_HUMAN,tr|B3KXD6|B3KXD6_HUMAN,tr|B5MCF9|B5MCF9_HUMAN,tr|H7C267|H7C267_HUMAN" 4 1140.539 0.89 58462 4260 2 1140.537191 571.2768 Pescadillo homolog OS=Homo sapiens OX=9606 GN=PES1 PE=1 SV=1 4.09 1436 - 292266 - - - -1.5843 - 2.525 0.23 - 557.1 1 2 0 -0.0018 10 0 0 0 4.50E+06 5.05E+06 - - - 3.3246 0.9989 221125_WJC_METTL3_EV_vs_WT_F05.04265.04265.2 0.0055 18-Sep R.LAQEEESEAK.R "sp|O00541|PESC_HUMAN,tr|B3KXD6|B3KXD6_HUMAN,tr|B5MCF9|B5MCF9_HUMAN,tr|H7C267|H7C267_HUMAN" 4 1132.5248 0.89 58465 4265 2 1132.521789 567.2697 Pescadillo homolog OS=Homo sapiens OX=9606 GN=PES1 PE=1 SV=1 4.09 1436.6 - 251547 - - - -2.6569 - 1.773 0.387 - 262.9 1 2 0 -0.003 10 0 0 0 4.50E+06 5.05E+06 - - - 3.4969 0.999 221125_WJC_METTL3_EV_vs_WT_F05.04269.04269.2 0.0202 12-Sep M.TGSNEFK[136.11].L "sp|O43684|BUB3_HUMAN,tr|J3QT28|J3QT28_HUMAN,tr|J3QSX4|J3QSX4_HUMAN" 3 789.3748 0.44 58467 4269 2 789.373368 395.6947 Mitotic checkpoint protein BUB3 OS=Homo sapiens OX=9606 GN=BUB3 PE=1 SV=1 5.66 1437.1 - 3.19E+06 - - - -1.8559 - 1.822 0.277 - 291.4 1 2 0 -0.0015 7 0 0 0 3.77E+07 8.54E+07 - - - 2.9874 0.7621 221125_WJC_METTL3_EV_vs_WT_F05.04271.04271.2 3.29 14-May K.LSPSPSSR.V "sp|P20700|LMNB1_HUMAN,sp|Q03252|LMNB2_HUMAN" 2 829.4294 0.62 58469 4271 2 829.42679 415.722 Lamin-B1 OS=Homo sapiens OX=9606 GN=LMNB1 PE=1 SV=2 9.75 1437.2 - 945746 - - - -3.1238 - 1.216 0.004 - 96.7 3 2 0 -0.0026 8 0 0 0 6.02E+08 9.64E+08 - - - -0.5536 0.9978 221125_WJC_METTL3_EV_vs_WT_F05.04275.04275.2 0.325 14-Aug K.EYEEDGAR.S sp|P61163|ACTZ_HUMAN 1 967.3883 1.84 58471 4275 2 967.386774 484.7014 Alpha-centractin OS=Homo sapiens OX=9606 GN=ACTR1A PE=1 SV=1 4 1437.8 - 490208 - - - -1.5816 - 1.294 0.311 - 334.9 1 2 0 -0.0015 8 0 0 0 5.30E+07 2.88E+07 - - - 2.1149 0.9767 221125_WJC_METTL3_EV_vs_WT_F05.04280.04280.2 0.395 16-Sep R.TGHWLNHGK[136.11].E sp|Q86U44|MTA70_HUMAN 1 1056.5345 0.4 58474 4280 2 1056.53083 529.2745 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 8.47 1438.3 - 1.39E+06 - - - -3.4377 - 1.382 0.178 - 146.5 1 2 0 -0.0036 9 0 0 0 6.38E+06 1.59E+07 - - - 1.2906 0.995 221125_WJC_METTL3_EV_vs_WT_F05.04282.04282.2 0.173 18-Jul K.TFGGGGGGAR.S sp|Q9H7E2|TDRD3_HUMAN 1 835.3937 0.99 58475 4282 2 835.393235 418.7041 Tudor domain-containing protein 3 OS=Homo sapiens OX=9606 GN=TDRD3 PE=1 SV=1 9.41 1438.5 - 1.33E+06 - - - -0.5135 - 1.34 0.172 - 119.3 1 2 0 -0.0004 10 0 0 0 3.90E+07 3.93E+07 - - - 1.1282 0.9809 221125_WJC_METTL3_EV_vs_WT_F05.04284.04284.2 6.87 12-May R.QLSEEER.G "sp|Q5UCC4|EMC10_HUMAN,sp|Q9Y6V0|PCLO_HUMAN,sp|Q5BJD5|TM41B_HUMAN,tr|M0R2A0|M0R2A0_HUMAN,tr|E9PJ42|E9PJ42_HUMAN" 5 889.4141 1.97 58477 4284 2 889.413447 445.7143 ER membrane protein complex subunit 10 OS=Homo sapiens OX=9606 GN=EMC10 PE=1 SV=1 4.25 1438.7 - 2.28E+06 - - - -0.7623 - 1.2 0.085 - 169.7 1 2 0 -0.0007 7 0 0 0 7.12E+07 3.62E+07 - - - 0.2463 0.997 221125_WJC_METTL3_EV_vs_WT_F05.04288.04288.2 0.147 14-Aug K.EYEEDGAR[166.11].S sp|P61163|ACTZ_HUMAN 1 977.3966 2 58479 4288 2 977.394299 489.7056 Alpha-centractin OS=Homo sapiens OX=9606 GN=ACTR1A PE=1 SV=1 4 1439.2 - 649314 - - - -2.3276 - 1.389 0.306 - 298.2 1 2 0 -0.0023 8 0 0 0 5.30E+07 2.64E+07 - - - 2.2914 0.9766 221125_WJC_METTL3_EV_vs_WT_F05.04295.04295.2 0.291 14-Jun K.AVEEMNGK.E "sp|Q13310|PABP4_HUMAN,tr|A0A7I2V5W9|A0A7I2V5W9_HUMAN,tr|B1ANR0|B1ANR0_HUMAN,tr|A0A7I2V4L7|A0A7I2V4L7_HUMAN,tr|H0YCC8|H0YCC8_HUMAN,tr|A0A7I2V598|A0A7I2V598_HUMAN,tr|H0Y5F5|H0Y5F5_HUMAN" 7 876.4011 0.66 58483 4295 2 876.399006 439.2078 Polyadenylate-binding protein 4 OS=Homo sapiens OX=9606 GN=PABPC4 PE=1 SV=1 4.53 1440.1 - 1.94E+06 - - - -2.4099 - 1.175 0.166 - 117.7 1 2 0 -0.0021 8 0 0 0 1.28E+08 1.93E+08 - - - 0.7528 0.9996 221125_WJC_METTL3_EV_vs_WT_F05.04301.04301.2 0.017 14-Sep R.QASTLEGR[166.11].R "sp|Q9Y2L1|RRP44_HUMAN,tr|F2Z2C0|F2Z2C0_HUMAN,tr|G3V1J5|G3V1J5_HUMAN" 3 870.4435 1.41 58487 4301 2 870.442147 436.229 Exosome complex exonuclease RRP44 OS=Homo sapiens OX=9606 GN=DIS3 PE=1 SV=2 6 1440.8 - 2.25E+06 - - - -1.5142 - 1.873 0.378 - 525.4 1 2 0 -0.0013 8 0 0 0 4.57E+08 3.24E+08 - - - 3.7251 0.9996 221125_WJC_METTL3_EV_vs_WT_F05.04306.04306.2 0.00254 16-Sep K.LGNQNVETK[136.11].Q sp|Q8WWC4|MAIP1_HUMAN 1 1009.5284 0.7 58489 4306 2 1009.527198 505.7715 "m-AAA protease-interacting protein 1, mitochondrial OS=Homo sapiens OX=9606 GN=MAIP1 PE=1 SV=1" 6 1441.5 - 328469 - - - -1.1649 - 1.744 0.389 - 234.1 1 2 0 -0.0012 9 0 0 0 3.42E+07 4.86E+07 - - - 3.5228 0.9992 221125_WJC_METTL3_EV_vs_WT_F05.04309.04309.2 0.0297 16-Jul R.LVEGESDNR[166.11].N sp|O94776|MTA2_HUMAN 1 1027.481 1.08 58490 4309 2 1027.47872 514.7478 Metastasis-associated protein MTA2 OS=Homo sapiens OX=9606 GN=MTA2 PE=1 SV=1 4.14 1441.9 - 424969 - - - -2.1927 - 1.55 0.437 - 168.8 1 2 0 -0.0023 9 0 0 0 5.18E+07 4.80E+07 - - - 3.5359 0.9994 221125_WJC_METTL3_EV_vs_WT_F05.04312.04312.2 0.00265 16-Sep K.LGNQNVETK.Q sp|Q8WWC4|MAIP1_HUMAN 1 1001.5142 0.68 58491 4312 2 1001.51259 501.7644 "m-AAA protease-interacting protein 1, mitochondrial OS=Homo sapiens OX=9606 GN=MAIP1 PE=1 SV=1" 6 1442.3 - 360920 - - - -1.5816 - 1.69 0.369 - 176.9 1 2 0 -0.0016 9 0 0 0 3.44E+07 5.08E+07 - - - 3.284 0.9996 221125_WJC_METTL3_EV_vs_WT_F05.04315.04315.2 0.00158 16-Jul R.LVEGESDNR.N sp|O94776|MTA2_HUMAN 1 1017.4727 1.08 58492 4315 2 1017.473082 509.7436 Metastasis-associated protein MTA2 OS=Homo sapiens OX=9606 GN=MTA2 PE=1 SV=1 4.14 1442.7 - 761020 - - - 0.3725 - 1.602 0.407 - 166.7 1 2 0 0.0004 9 0 0 0 5.18E+07 4.80E+07 - - - 3.4103 0.9986 221125_WJC_METTL3_EV_vs_WT_F05.04317.04317.2 0.0268 14-Jul R.QASTLEGR.R "sp|Q9Y2L1|RRP44_HUMAN,tr|F2Z2C0|F2Z2C0_HUMAN,tr|G3V1J5|G3V1J5_HUMAN" 3 860.4352 1.01 58493 4317 2 860.434071 431.2249 Exosome complex exonuclease RRP44 OS=Homo sapiens OX=9606 GN=DIS3 PE=1 SV=2 6 1442.9 - 1.13E+07 - - - -1.3063 - 1.428 0.305 - 260.6 1 2 0 -0.0011 8 0 0 0 4.61E+08 4.57E+08 - - - 2.3679 0.9328 221125_WJC_METTL3_EV_vs_WT_F05.04328.04328.2 0.099 14-Aug R.LREGQTLR.D sp|O00165|HAX1_HUMAN 1 971.5512 1.37 58498 4328 2 971.548778 486.7829 HCLS1-associated protein X-1 OS=Homo sapiens OX=9606 GN=HAX1 PE=1 SV=2 9.6 1444.3 - 854141 - - - -2.5217 - 1.5 0.205 - 151.2 1 2 1 -0.0024 8 0 0 0 2.42E+07 1.76E+07 - - - 1.7772 0.9996 221125_WJC_METTL3_EV_vs_WT_F05.04340.04340.2 0.02 14-Sep K.NLAC[160.03]EESK[136.11].R sp|O95347|SMC2_HUMAN 1 957.4317 0.86 58504 4340 2 957.43213 479.7231 Structural maintenance of chromosomes protein 2 OS=Homo sapiens OX=9606 GN=SMC2 PE=1 SV=2 4.53 1445.9 - 1.16E+06 - - - 0.4533 - 1.522 0.397 - 297.3 1 2 0 0.0004 8 0 0 0 2.52E+07 2.95E+07 - - - 3.2399 0.9758 221125_WJC_METTL3_EV_vs_WT_F05.04342.04342.2 0.159 16-May K.LTPTHGEMR.K "sp|Q8NE71|ABCF1_HUMAN,tr|Q5STZ8|Q5STZ8_HUMAN,tr|H0YGW7|H0YGW7_HUMAN" 3 1040.5073 0.02 58506 4342 2 1040.509087 521.2609 ATP-binding cassette sub-family F member 1 OS=Homo sapiens OX=9606 GN=ABCF1 PE=1 SV=2 6.75 1446.2 - 134270 - - - 1.704 - 1.078 0.163 - 91.6 1 2 0 0.0018 9 0 0 0 2.93E+06 1.74E+08 - - - 0.4617 0.9983 221125_WJC_METTL3_EV_vs_WT_F05.04345.04345.2 0.124 12-Jul K.ANEVISK[136.11].L "sp|P50990|TCPQ_HUMAN,tr|H7C2U0|H7C2U0_HUMAN" 2 767.4269 0.14 58507 4345 2 767.426031 384.7207 T-complex protein 1 subunit theta OS=Homo sapiens OX=9606 GN=CCT8 PE=1 SV=4 6.05 1446.6 - 7.88E+06 - - - -1.092 - 1.54 0.231 - 327.1 1 2 0 -0.0008 7 0 0 0 5.13E+09 3.57E+10 - - - 2.115 0.9988 221125_WJC_METTL3_EV_vs_WT_F05.04346.04346.2 0.018 14-Aug K.NLAC[160.03]EESK.R sp|O95347|SMC2_HUMAN 1 949.4175 0.85 58508 4346 2 949.41644 475.716 Structural maintenance of chromosomes protein 2 OS=Homo sapiens OX=9606 GN=SMC2 PE=1 SV=2 4.53 1446.7 - 1.13E+06 - - - -1.1123 - 1.243 0.371 - 267.3 1 2 0 -0.0011 8 0 0 0 2.52E+07 2.98E+07 - - - 2.4369 0.9728 221125_WJC_METTL3_EV_vs_WT_F05.04348.04348.2 3.19 16-Jul R.SAVPPGADK[136.11].K "sp|P46783|RS10_HUMAN,tr|F6U211|F6U211_HUMAN,tr|A0A1W2PQS6|A0A1W2PQS6_HUMAN,tr|A0A2R8YFH6|A0A2R8YFH6_HUMAN,tr|A0A2R8Y7H1|A0A2R8Y7H1_HUMAN,tr|S4R435|S4R435_HUMAN" 6 848.4483 1.62 58509 4348 2 848.447451 425.2314 40S ribosomal protein S10 OS=Homo sapiens OX=9606 GN=RPS10 PE=1 SV=1 5.55 1446.9 - 9.63E+06 - - - -1.0384 - 1.139 0.09 - 163.7 1 2 0 -0.0009 9 0 0 0 6.85E+08 4.22E+08 - - - 0.082 0.9995 221125_WJC_METTL3_EV_vs_WT_F05.04351.04351.2 0.0311 16-Sep R.ASGAQLEAK.V sp|Q9BVC6|TM109_HUMAN 1 873.4556 0.88 58511 4351 2 873.455522 437.7351 Transmembrane protein 109 OS=Homo sapiens OX=9606 GN=TMEM109 PE=1 SV=1 6.05 1447.1 - 4.17E+06 - - - -0.0847 - 1.804 0.318 - 243.4 1 2 0 -0.0001 9 0 0 0 1.04E+08 1.18E+08 - - - 3.0966 0.8995 221125_WJC_METTL3_EV_vs_WT_F05.04357.04357.2 3.39 14-May R.IVGGQEC[160.03]K.D "sp|P00742|FA10_HUMAN,tr|B7ZBK1|B7ZBK1_HUMAN,tr|Q5JVE8|Q5JVE8_HUMAN" 3 889.4328 0.71 58515 4357 2 889.431861 445.7237 Coagulation factor X OS=Homo sapiens OX=9606 GN=F10 PE=1 SV=2 5.99 1447.7 - 2.94E+06 - - - -1.0018 - 0.864 0.101 - 45.6 2 2 0 -0.0009 8 0 0 0 4.04E+08 5.73E+08 - - - -0.7886 0.9718 221125_WJC_METTL3_EV_vs_WT_F05.04358.04358.2 1.06 12-Jul R.LEAEQQR[166.11].C sp|Q8N137|CNTRB_HUMAN 1 882.4435 2.67 58516 4358 2 882.44154 442.229 Centrobin OS=Homo sapiens OX=9606 GN=CNTROB PE=1 SV=1 4.53 1447.7 - 2.93E+06 - - - -2.1814 - 1.603 0.026 - 208.6 3 2 0 -0.0019 7 0 0 0 2.63E+08 9.84E+07 - - - 0.5145 0.9878 221125_WJC_METTL3_EV_vs_WT_F05.04359.04359.2 0.117 16-Aug R.IQDAGPASR[166.11].D "sp|Q7Z2W4|ZCCHV_HUMAN,tr|C9J6P4|C9J6P4_HUMAN,tr|A0A7P0T8C6|A0A7P0T8C6_HUMAN" 3 923.47 0.78 58517 4359 2 923.466627 462.7423 Zinc finger CCCH-type antiviral protein 1 OS=Homo sapiens OX=9606 GN=ZC3HAV1 PE=1 SV=3 5.84 1447.8 - 2.33E+06 - - - -3.6677 - 1.591 0.209 - 152 1 2 0 -0.0034 9 0 0 0 8.52E+07 1.10E+08 - - - 1.927 0.9963 221125_WJC_METTL3_EV_vs_WT_F05.04364.04364.2 0.551 16-Apr K.VMEEESTEK[136.11].K "sp|Q4G0J3|LARP7_HUMAN,tr|D6RBH8|D6RBH8_HUMAN,tr|D6RF22|D6RF22_HUMAN,tr|D6RFF0|D6RFF0_HUMAN,tr|D6RF49|D6RF49_HUMAN,tr|D6RAF3|D6RAF3_HUMAN" 6 1088.4787 0.59 58520 4364 2 1088.477943 545.2466 La-related protein 7 OS=Homo sapiens OX=9606 GN=LARP7 PE=1 SV=1 4.09 1448.4 - 165643 - - - -0.701 - 0.98 0.324 - 49.1 1 2 0 -0.0008 9 0 0 0 1.34E+06 2.29E+06 - - - 1.3754 0.9925 221125_WJC_METTL3_EV_vs_WT_F05.04377.04377.2 0.0204 14-Aug K.LNQMDQDK[136.11].V "sp|P49736|MCM2_HUMAN,tr|H0Y8E6|H0Y8E6_HUMAN" 2 998.4582 1.28 58524 4377 2 998.454568 500.2364 DNA replication licensing factor MCM2 OS=Homo sapiens OX=9606 GN=MCM2 PE=1 SV=4 4.21 1450.1 - 506788 - - - -3.6827 - 1.156 0.389 - 126 1 2 0 -0.0037 8 0 0 0 1.07E+07 8.31E+06 - - - 2.3502 0.9744 221125_WJC_METTL3_EV_vs_WT_F05.04378.04378.2 1.74 12-Jul K.AIAEIK[136.11]K[136.11].M "sp|P21912|SDHB_HUMAN,sp|Q8ND61|CC020_HUMAN" 2 787.5138 0.42 58525 4378 2 787.511854 394.7642 "Succinate dehydrogenase [ubiquinone] iron-sulfur subunit, mitochondrial OS=Homo sapiens OX=9606 GN=SDHB PE=1 SV=3" 8.64 1450.2 - 1.19E+06 - - - -2.5219 - 1.327 0.11 - 145.8 1 2 0 -0.002 7 0 0 0 1.14E+07 2.74E+07 - - - 0.7493 0.9905 221125_WJC_METTL3_EV_vs_WT_F05.04382.04382.2 0.224 16-Aug R.EVVETQEGK.T "sp|Q9NVS2|RT18A_HUMAN,tr|Q5QPA5|Q5QPA5_HUMAN" 2 1017.4979 0.74 58527 4382 2 1017.495402 509.7562 "39S ribosomal protein S18a, mitochondrial OS=Homo sapiens OX=9606 GN=MRPS18A PE=1 SV=1" 4.25 1450.8 - 306842 - - - -2.4108 - 1.227 0.24 - 206.3 1 2 0 -0.0025 9 0 0 0 4.92E+06 6.68E+06 - - - 1.4047 0.9199 221125_WJC_METTL3_EV_vs_WT_F05.04385.04385.2 1.49 14-Jul K.FGTSETSK.T "sp|P49792|RBP2_HUMAN,sp|P49792|RBP2_HUMAN" 2 855.3974 2 58528 4385 2 855.394945 428.706 E3 SUMO-protein ligase RanBP2 OS=Homo sapiens OX=9606 GN=RANBP2 PE=1 SV=2 6 1451.1 - 6.86E+06 - - - -2.884 - 1.214 0.069 - 118.1 1 2 0 -0.0025 8 0 0 0 2.23E+08 1.11E+08 - - - 0.1347 0.9948 221125_WJC_METTL3_EV_vs_WT_F05.04389.04389.2 0.27 14-Jul K.TQTAVVQR[166.11].D "sp|Q14254|FLOT2_HUMAN,tr|E7EMK3|E7EMK3_HUMAN,tr|K7EKW9|K7EKW9_HUMAN,tr|J3QLD9|J3QLD9_HUMAN" 4 911.5064 1.35 58530 4389 2 911.503698 456.7605 Flotillin-2 OS=Homo sapiens OX=9606 GN=FLOT2 PE=1 SV=2 9.41 1451.6 - 3.81E+06 - - - -2.9643 - 1.655 0.224 - 306.1 1 2 0 -0.0027 8 0 0 0 9.81E+07 7.29E+07 - - - 2.2141 0.9897 221125_WJC_METTL3_EV_vs_WT_F05.04391.04391.2 0.0642 12-Jul K.LTSDDVK[136.11].E "sp|P62277|RS13_HUMAN,sp|Q15751|HERC1_HUMAN,tr|J3KMX5|J3KMX5_HUMAN,tr|H0YK45|H0YK45_HUMAN,tr|E9PS50|E9PS50_HUMAN" 5 784.4058 2.81 58531 4391 2 784.403515 393.2102 40S ribosomal protein S13 OS=Homo sapiens OX=9606 GN=RPS13 PE=1 SV=2 4.21 1451.8 - 1.36E+06 - - - -2.9118 - 1.587 0.152 - 142.7 1 2 0 -0.0023 7 0 0 0 8.58E+07 3.05E+07 - - - 1.6263 0.992 221125_WJC_METTL3_EV_vs_WT_F05.04395.04395.2 0.0223 14-Aug R.ADDNATIR.V "sp|O75821|EIF3G_HUMAN,tr|K7ER90|K7ER90_HUMAN,tr|K7EL20|K7EL20_HUMAN,tr|K7ENA8|K7ENA8_HUMAN" 4 874.4145 2.07 58534 4395 2 874.411175 438.2145 Eukaryotic translation initiation factor 3 subunit G OS=Homo sapiens OX=9606 GN=EIF3G PE=1 SV=2 4.21 1452.2 - 1.30E+07 - - - -3.7557 - 1.422 0.303 - 253.9 1 2 0 -0.0033 8 0 0 0 3.36E+08 1.62E+08 - - - 2.3397 0.9939 221125_WJC_METTL3_EV_vs_WT_F05.04397.04397.2 0.0536 12-Jul K.TSQVPVK[136.11].H sp|Q9NXV2|KCTD5_HUMAN 1 765.4476 0.31 58535 4397 2 765.445006 383.7311 BTB\POZ domain-containing protein KCTD5 OS=Homo sapiens OX=9606 GN=KCTD5 PE=1 SV=1 8.41 1452.4 - 1.45E+08 - - - -3.3941 - 1.487 0.278 - 268.5 1 2 0 -0.0026 7 0 0 0 1.23E+09 3.95E+09 - - - 2.3507 0.9201 221125_WJC_METTL3_EV_vs_WT_F05.04398.04398.2 0.96 14-Aug K.NAENLEGK[136.11].V "sp|Q15643|TRIPB_HUMAN,tr|H0YJI2|H0YJI2_HUMAN,tr|H0YJ97|H0YJ97_HUMAN" 3 881.4334 0.45 58536 4398 2 881.430489 441.724 Thyroid receptor-interacting protein 11 OS=Homo sapiens OX=9606 GN=TRIP11 PE=1 SV=3 4.53 1452.4 - 8.20E+06 - - - -3.3151 - 0.993 0.179 - 159.3 1 2 0 -0.0029 8 0 0 0 1.46E+08 3.25E+08 - - - 0.341 0.9996 221125_WJC_METTL3_EV_vs_WT_F05.04400.04400.2 0.000571 16-Aug R.IVQNSNGYK[136.11].L "sp|O60701|UGDH_HUMAN,tr|E7EV97|E7EV97_HUMAN,tr|E7ER83|E7ER83_HUMAN,tr|E7ETF4|E7ETF4_HUMAN" 4 1029.5335 1.1 58538 4400 2 1029.53154 515.774 UDP-glucose 6-dehydrogenase OS=Homo sapiens OX=9606 GN=UGDH PE=1 SV=1 8.59 1452.6 - 716389 - - - -1.864 - 1.88 0.447 - 163.2 1 2 0 -0.0019 9 0 0 0 2.89E+07 2.62E+07 - - - 4.1682 0.9971 221125_WJC_METTL3_EV_vs_WT_F05.04403.04403.2 0.0217 12-Aug K.EAEDNIR.E sp|O60925|PFD1_HUMAN 1 845.3879 1.23 58539 4403 2 845.385774 423.7012 Prefoldin subunit 1 OS=Homo sapiens OX=9606 GN=PFDN1 PE=1 SV=2 4.14 1453 - 1.14E+07 - - - -2.5267 - 1.427 0.309 - 349.6 1 2 0 -0.0021 7 0 0 0 2.74E+08 2.23E+08 - - - 2.4493 0.9782 221125_WJC_METTL3_EV_vs_WT_F05.04405.04405.2 0.519 12-Jul R.QIAAIHK[136.11].D sp|Q9UQE7|SMC3_HUMAN 1 787.4796 0.77 58540 4405 2 787.476847 394.7471 Structural maintenance of chromosomes protein 3 OS=Homo sapiens OX=9606 GN=SMC3 PE=1 SV=2 8.76 1453.2 - 1.13E+06 - - - -3.4617 - 1.352 0.184 - 177.9 1 2 0 -0.0027 7 0 0 0 2.41E+07 3.15E+07 - - - 1.3548 0.9492 221125_WJC_METTL3_EV_vs_WT_F05.04406.04406.2 0.289 14-Jul K.LQQEEVQK.K sp|Q86UP2|KTN1_HUMAN 1 1000.5189 2.49 58541 4406 2 1000.515102 501.2667 Kinectin OS=Homo sapiens OX=9606 GN=KTN1 PE=1 SV=1 4.53 1453.3 - 351925 - - - -3.821 - 1.513 0.085 - 119.3 1 2 0 -0.0038 8 0 0 0 4.87E+07 1.96E+07 - - - 0.9165 0.9963 221125_WJC_METTL3_EV_vs_WT_F05.04407.04407.2 0.00927 14-Sep R.IGQQNEVR.V "sp|P51531|SMCA2_HUMAN,sp|P51532|SMCA4_HUMAN,tr|A0A2R8Y5K3|A0A2R8Y5K3_HUMAN,tr|A0A2R8Y7S2|A0A2R8Y7S2_HUMAN,tr|A0A2R8Y7F3|A0A2R8Y7F3_HUMAN,tr|A0A2R8YGG3|A0A2R8YGG3_HUMAN,tr|A0A0U1RQZ9|A0A0U1RQZ9_HUMAN,tr|A0A2R8Y523|A0A2R8Y523_HUMAN,tr|A0A2R8Y6V2|A0A2R8Y6V2_HUMAN,tr|Q9HBD4|Q9HBD4_HUMAN,tr|A0A2R8Y440|A0A2R8Y440_HUMAN,tr|F6VDE0|F6VDE0_HUMAN,tr|A0A2R8YDA1|A0A2R8YDA1_HUMAN,tr|A0A2R8Y7Y7|A0A2R8Y7Y7_HUMAN,tr|A0A2R8YF58|A0A2R8YF58_HUMAN,tr|A0A2R8Y526|A0A2R8Y526_HUMAN,tr|A0A2R8YG32|A0A2R8YG32_HUMAN,tr|A0A2R8Y6N0|A0A2R8Y6N0_HUMAN,tr|A0A2R8YF80|A0A2R8YF80_HUMAN,tr|A0A2R8Y4P4|A0A2R8Y4P4_HUMAN,tr|A0A2R8Y4C5|A0A2R8Y4C5_HUMAN" 21 942.4883 0.62 58542 4407 2 942.484897 472.2514 Probable global transcription activator SNF2L2 OS=Homo sapiens OX=9606 GN=SMARCA2 PE=1 SV=2 6 1453.4 - 727443 - - - -3.6032 - 1.802 0.291 - 255.5 1 2 0 -0.0034 8 0 0 0 3.55E+07 5.76E+07 - - - 2.9653 0.972 221125_WJC_METTL3_EV_vs_WT_F05.04417.04417.2 0.593 12-Jun R.AEDLNTR.V "sp|Q9Y3B3|TMED7_HUMAN,tr|A0A0A6YYA0|A0A0A6YYA0_HUMAN" 2 817.393 2.62 58546 4417 2 817.389641 409.7038 Transmembrane emp24 domain-containing protein 7 OS=Homo sapiens OX=9606 GN=TMED7 PE=1 SV=2 4.37 1454.7 - 3.25E+06 - - - -4.1045 - 1.476 0.168 - 177.1 1 2 0 -0.0034 7 0 0 0 1.23E+08 4.71E+07 - - - 1.5144 0.9992 221125_WJC_METTL3_EV_vs_WT_F05.04418.04418.2 0.000141 16-Sep K.VSADNTVGR.F "sp|O00303|EIF3F_HUMAN,tr|H0YDT6|H0YDT6_HUMAN" 2 917.4567 1.26 58547 4418 2 917.453661 459.7356 Eukaryotic translation initiation factor 3 subunit F OS=Homo sapiens OX=9606 GN=EIF3F PE=1 SV=1 5.81 1454.8 - 3.74E+06 - - - -3.2677 - 2.05 0.464 - 250.5 1 2 0 -0.003 9 0 0 0 2.63E+08 2.09E+08 - - - 4.5439 0.9731 221125_WJC_METTL3_EV_vs_WT_F05.04420.04420.2 0.429 14-Aug K.LHGELQDR[166.11].K sp|Q9NR30|DDX21_HUMAN 1 976.4966 0.97 58549 4420 2 976.493492 489.2556 Nucleolar RNA helicase 2 OS=Homo sapiens OX=9606 GN=DDX21 PE=1 SV=5 5.32 1455 - 1.12E+06 - - - -3.1449 - 1.328 0.154 - 263.8 1 2 0 -0.0031 8 0 0 0 2.24E+07 2.32E+07 - - - 1.033 0.9985 221125_WJC_METTL3_EV_vs_WT_F05.04427.04427.2 0.00154 18-Oct K.DPGGGGGPVR[166.11].A sp|Q8IU81|I2BP1_HUMAN 1 877.4281 1.24 58552 4427 2 877.425016 439.7214 Interferon regulatory factor 2-binding protein 1 OS=Homo sapiens OX=9606 GN=IRF2BP1 PE=1 SV=1 5.84 1455.9 - 7.39E+06 - - - -3.5707 - 1.919 0.415 - 343.6 1 2 0 -0.0031 10 0 0 0 2.70E+08 2.17E+08 - - - 3.9246 0.9936 221125_WJC_METTL3_EV_vs_WT_F05.04434.04434.2 0.00557 14-Aug R.EQAEQTLK.Q sp|Q9UI36|DACH1_HUMAN 1 945.4767 2.05 58556 4434 2 945.473751 473.7456 Dachshund homolog 1 OS=Homo sapiens OX=9606 GN=DACH1 PE=1 SV=4 4.53 1456.6 - 1.86E+06 - - - -3.1455 - 1.647 0.218 - 194.3 1 2 0 -0.003 8 0 0 0 6.60E+08 3.21E+08 - - - 2.155 0.9956 221125_WJC_METTL3_EV_vs_WT_F05.04436.04436.2 0.376 12-Aug K.QTLENER.G sp|P35579|MYH9_HUMAN 1 888.4301 0.97 58557 4436 2 888.429361 445.2223 Myosin-9 OS=Homo sapiens OX=9606 GN=MYH9 PE=1 SV=4 4.53 1456.8 - 4.98E+06 - - - -0.8431 - 1.621 0.096 - 232.5 1 2 0 -0.0007 7 0 0 0 2.03E+08 2.10E+08 - - - 1.2804 0.7638 221125_WJC_METTL3_EV_vs_WT_F05.04443.04443.2 0.169 14-Sep L.EDEEEVK[136.11]K[136.11].E "sp|Q9NQ66|PLCB1_HUMAN,tr|H0YCJ2|H0YCJ2_HUMAN,tr|A0A0D9SF51|A0A0D9SF51_HUMAN,tr|A0A0D9SG17|A0A0D9SG17_HUMAN,tr|A0A087WW73|A0A087WW73_HUMAN,tr|A0A1B0GWB6|A0A1B0GWB6_HUMAN,tr|Q8IV92|Q8IV92_HUMAN,tr|A0A087WT80|A0A087WT80_HUMAN" 8 1020.4946 1 58559 4443 2 1020.491474 511.2546 "1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase beta-1 OS=Homo sapiens OX=9606 GN=PLCB1 PE=1 SV=1" 4.25 1457.7 - 2.29E+06 - - - -3.0828 - 1.861 0.188 - 336.7 1 1 0 -0.0031 8 0 0 0 6.13E+07 6.16E+07 - - - 2.3018 0.9678 221125_WJC_METTL3_EV_vs_WT_F05.04445.04445.2 0.254 14-Jun R.TVVDSEGR.T "sp|O00165|HAX1_HUMAN,tr|Q5VYD6|Q5VYD6_HUMAN,tr|E9PIQ7|E9PIQ7_HUMAN" 3 861.4192 1.3 58560 4445 2 861.41655 431.7169 HCLS1-associated protein X-1 OS=Homo sapiens OX=9606 GN=HAX1 PE=1 SV=2 4.37 1458 - 4.51E+06 - - - -3.0891 - 1.185 0.179 - 116 1 2 0 -0.0027 8 0 0 0 1.85E+08 1.42E+08 - - - 0.8742 0.9982 221125_WJC_METTL3_EV_vs_WT_F05.04450.04450.2 0.000409 18-Aug K.DPGGGGGPVR.A sp|Q8IU81|I2BP1_HUMAN 1 867.4199 0.89 58562 4450 2 867.416427 434.7172 Interferon regulatory factor 2-binding protein 1 OS=Homo sapiens OX=9606 GN=IRF2BP1 PE=1 SV=1 5.84 1458.6 - 6.65E+06 - - - -3.9796 - 1.689 0.485 - 215.3 1 2 0 -0.0035 10 0 0 0 2.76E+08 3.08E+08 - - - 4.0852 0.9967 221125_WJC_METTL3_EV_vs_WT_F05.04457.04457.2 0.000196 14-Aug K.MDQPPQAK[136.11].K sp|P34932|HSP74_HUMAN 1 921.447 0.22 58565 4457 2 921.443086 461.7308 Heat shock 70 kDa protein 4 OS=Homo sapiens OX=9606 GN=HSPA4 PE=1 SV=4 5.59 1459.4 - 3.51E+06 - - - -4.1956 - 1.514 0.44 - 263.5 1 2 0 -0.0039 8 0 0 0 2.55E+07 1.14E+08 - - - 3.5405 0.9781 221125_WJC_METTL3_EV_vs_WT_F05.04462.04462.2 0.000431 14-Sep R.VTTEQYQK.A "sp|Q9NX63|MIC19_HUMAN,tr|F8WAR4|F8WAR4_HUMAN,tr|C9JRZ6|C9JRZ6_HUMAN" 3 995.4924 1.89 58567 4462 2 995.485302 498.7535 MICOS complex subunit MIC19 OS=Homo sapiens OX=9606 GN=CHCHD3 PE=1 SV=1 5.97 1460 - 1.56E+06 - - - -7.105 - 2.078 0.329 - 304.2 1 2 0 -0.0071 8 0 0 0 5.65E+07 2.99E+07 - - - 3.6747 0.9945 221125_WJC_METTL3_EV_vs_WT_F05.04464.04464.2 0.0654 12-Jul R.C[160.03]EDGC[160.03]IR.G sp|Q92947|GCDH_HUMAN 1 908.348 1.22 58568 4464 2 908.344399 455.1813 "Glutaryl-CoA dehydrogenase, mitochondrial OS=Homo sapiens OX=9606 GN=GCDH PE=1 SV=1" 4.37 1460.2 - 2.81E+06 - - - -4.0051 - 1.356 0.386 - 318.3 1 2 0 -0.0036 7 0 0 0 1.20E+08 9.81E+07 - - - 2.8558 0.997 221125_WJC_METTL3_EV_vs_WT_F05.04468.04468.2 0.0138 16-Oct R.SAVPPGADK.K "sp|P46783|RS10_HUMAN,tr|F6U211|F6U211_HUMAN,tr|A0A1W2PQS6|A0A1W2PQS6_HUMAN,tr|A0A2R8YFH6|A0A2R8YFH6_HUMAN,tr|A0A2R8Y7H1|A0A2R8Y7H1_HUMAN,tr|S4R435|S4R435_HUMAN" 6 840.4341 1.25 58570 4468 2 840.430896 421.2243 40S ribosomal protein S10 OS=Homo sapiens OX=9606 GN=RPS10 PE=1 SV=1 5.55 1460.7 - 1.39E+07 - - - -3.8504 - 1.652 0.391 - 325.4 1 2 0 -0.0032 9 0 0 0 6.92E+08 5.55E+08 - - - 3.3802 0.9977 221125_WJC_METTL3_EV_vs_WT_F05.04472.04472.2 0.0123 14-Aug R.VTTEQYQK[136.11].A "sp|Q9NX63|MIC19_HUMAN,tr|F8WAR4|F8WAR4_HUMAN,tr|C9JRZ6|C9JRZ6_HUMAN" 3 1003.5066 1.88 58572 4472 2 1003.503373 502.7606 MICOS complex subunit MIC19 OS=Homo sapiens OX=9606 GN=CHCHD3 PE=1 SV=1 5.97 1461.2 - 1.57E+06 - - - -3.1908 - 1.734 0.331 - 235.6 1 2 0 -0.0032 8 0 0 0 5.62E+07 2.99E+07 - - - 3.1448 0.9829 221125_WJC_METTL3_EV_vs_WT_F05.04474.04474.2 0.0601 16-Aug K.AGVQSVGEK[136.11].E "sp|Q86VM9|ZCH18_HUMAN,tr|E7ERS3|E7ERS3_HUMAN" 2 881.4698 0.81 58574 4474 2 881.465656 441.7422 Zinc finger CCCH domain-containing protein 18 OS=Homo sapiens OX=9606 GN=ZC3H18 PE=1 SV=2 6.05 1461.4 - 1.56E+06 - - - -4.6967 - 1.579 0.258 - 209.1 1 2 0 -0.0041 9 0 0 0 3.09E+07 3.82E+07 - - - 2.2668 0.9996 221125_WJC_METTL3_EV_vs_WT_F05.04479.04479.2 0.00394 12-Sep R.C[160.03]EDGC[160.03]IR[166.11].G sp|Q92947|GCDH_HUMAN 1 918.3563 1.22 58577 4479 2 918.35451 460.1854 "Glutaryl-CoA dehydrogenase, mitochondrial OS=Homo sapiens OX=9606 GN=GCDH PE=1 SV=1" 4.37 1462 - 4.88E+06 - - - -1.9568 - 1.759 0.457 - 491.8 1 2 0 -0.0018 7 0 0 0 1.20E+08 9.81E+07 - - - 4.2053 0.9978 221125_WJC_METTL3_EV_vs_WT_F05.04486.04486.2 0.17 14-Jun R.QLQEDAAR.L "sp|Q01082|SPTB2_HUMAN,tr|A0A087WUZ3|A0A087WUZ3_HUMAN" 2 929.4567 2.25 58582 4486 2 929.455178 465.7356 "Spectrin beta chain, non-erythrocytic 1 OS=Homo sapiens OX=9606 GN=SPTBN1 PE=1 SV=2" 4.37 1462.9 - 4.14E+06 - - - -1.5934 - 1.361 0.29 - 132.8 1 2 0 -0.0015 8 0 0 0 1.11E+08 4.95E+07 - - - 2.1121 0.9814 221125_WJC_METTL3_EV_vs_WT_F05.04487.04487.2 0.0984 14-Jun K.QAEEIGEK.L sp|Q15149|PLEC_HUMAN 1 902.4345 2.62 58583 4487 2 902.431699 452.2245 Plectin OS=Homo sapiens OX=9606 GN=PLEC PE=1 SV=3 4.25 1462.9 - 856410 - - - -3.1326 - 1.239 0.218 - 156.1 1 2 0 -0.0028 8 0 0 0 4.99E+07 1.91E+07 - - - 1.2966 0.9914 221125_WJC_METTL3_EV_vs_WT_F05.04493.04493.2 0.000763 16-Sep K.LVEEQNAEK[136.11].A "sp|Q5F1R6|DJC21_HUMAN,tr|A0A2R8Y4N5|A0A2R8Y4N5_HUMAN,tr|A0A2R8Y4Q0|A0A2R8Y4Q0_HUMAN,tr|A0A2R8Y534|A0A2R8Y534_HUMAN" 4 1066.5386 1.12 58587 4493 2 1066.534417 534.2766 DnaJ homolog subfamily C member 21 OS=Homo sapiens OX=9606 GN=DNAJC21 PE=1 SV=2 4.25 1463.7 - 293428 - - - -3.9258 - 1.632 0.262 - 236 1 2 0 -0.0042 9 0 0 0 1.52E+07 1.35E+07 - - - 2.3919 0.9951 221125_WJC_METTL3_EV_vs_WT_F05.04498.04498.2 0.552 12-Aug K.QVSNIGR[166.11].K sp|Q9UJV9|DDX41_HUMAN 1 782.4274 0.77 58590 4498 2 782.425032 392.221 Probable ATP-dependent RNA helicase DDX41 OS=Homo sapiens OX=9606 GN=DDX41 PE=1 SV=2 9.75 1464.3 - 5.79E+06 - - - -3.0533 - 1.452 0.284 - 369.2 1 2 0 -0.0024 7 0 0 0 9.31E+07 1.21E+08 - - - 2.3196 0.9586 221125_WJC_METTL3_EV_vs_WT_F05.04499.04499.2 2.54 14-Jul K.QVETGVAK.M sp|Q13873|BMPR2_HUMAN 1 830.4498 0.96 58591 4499 2 830.448274 416.2322 Bone morphogenetic protein receptor type-2 OS=Homo sapiens OX=9606 GN=BMPR2 PE=1 SV=2 6 1464.3 - 966520 - - - -1.8159 - 1.066 0.116 - 107.3 1 2 0 -0.0015 8 0 0 0 5.85E+07 6.09E+07 - - - 0.0901 0.9855 221125_WJC_METTL3_EV_vs_WT_F05.04500.04500.2 0.127 12-Jul R.QEEQVVR[166.11].Q "sp|Q12788|TBL3_HUMAN,tr|J3KNP2|J3KNP2_HUMAN" 2 896.4591 1.16 58592 4500 2 896.456253 449.2368 Transducin beta-like protein 3 OS=Homo sapiens OX=9606 GN=TBL3 PE=1 SV=2 4.53 1464.5 - 649654 - - - -3.1926 - 1.485 0.166 - 341 1 2 0 -0.0029 7 0 0 0 7.77E+07 6.69E+07 - - - 1.5191 0.8978 221125_WJC_METTL3_EV_vs_WT_F05.04505.04505.2 0.248 12-Jul R.QEEQVVR.Q "sp|Q12788|TBL3_HUMAN,tr|J3KNP2|J3KNP2_HUMAN" 2 886.4508 1.16 58594 4505 2 886.445447 444.2327 Transducin beta-like protein 3 OS=Homo sapiens OX=9606 GN=TBL3 PE=1 SV=2 4.53 1465.1 - 1.41E+06 - - - -6.0895 - 1.501 0.165 - 270.4 1 2 0 -0.0054 7 0 0 0 7.86E+07 6.75E+07 - - - 1.5448 0.9819 221125_WJC_METTL3_EV_vs_WT_F05.04507.04507.2 0.0818 12-Jul K.QVSNIGR.K sp|Q9UJV9|DDX41_HUMAN 1 772.4192 0.73 58595 4507 2 772.417451 387.2169 Probable ATP-dependent RNA helicase DDX41 OS=Homo sapiens OX=9606 GN=DDX41 PE=1 SV=2 9.75 1465.3 - 4.49E+06 - - - -2.2009 - 1.279 0.137 - 189.8 1 2 0 -0.0017 7 0 0 0 9.35E+07 1.28E+08 - - - 0.8321 0.9728 221125_WJC_METTL3_EV_vs_WT_F05.04509.04509.2 0.00216 14-Aug F.YTNEEVAK.N "sp|P43243|MATR3_HUMAN,tr|B3KM87|B3KM87_HUMAN,tr|A8MXP9|A8MXP9_HUMAN,tr|A0A0R4J2E8|A0A0R4J2E8_HUMAN" 4 952.4502 1.03 58597 4509 2 952.448765 477.2324 Matrin-3 OS=Homo sapiens OX=9606 GN=MATR3 PE=1 SV=2 4.53 1465.4 - 4.99E+06 - - - -1.4814 - 1.481 0.452 - 162.7 1 1 0 -0.0014 8 0 0 0 1.66E+08 1.62E+08 - - - 3.5634 0.9257 221125_WJC_METTL3_EV_vs_WT_F05.04510.04510.2 3.37 12-Jun K.AHPPELK[136.11].K "sp|P62308|RUXG_HUMAN,sp|A8MWD9|RUXGL_HUMAN,tr|C9JVQ0|C9JVQ0_HUMAN" 3 798.4479 2.54 58598 4510 2 798.446395 400.2312 Small nuclear ribonucleoprotein G OS=Homo sapiens OX=9606 GN=SNRPG PE=1 SV=1 6.79 1465.6 - 1.06E+06 - - - -1.9325 - 1.065 0.069 - 166.8 1 2 0 -0.0015 7 0 0 0 9.37E+07 3.69E+07 - - - -0.2503 0.9583 221125_WJC_METTL3_EV_vs_WT_F05.04517.04517.2 0.441 12-Jun R.YSGGNYR[166.11].D sp|P98179|RBM3_HUMAN 1 825.3645 0.97 58600 4517 2 825.362834 413.6895 RNA-binding protein 3 OS=Homo sapiens OX=9606 GN=RBM3 PE=1 SV=1 8.59 1466.5 - 3.39E+06 - - - -2.0015 - 1.071 0.123 - 84.8 1 2 0 -0.0017 7 0 0 0 3.62E+08 3.73E+08 - - - 0.1663 0.9984 221125_WJC_METTL3_EV_vs_WT_F05.04522.04522.2 0.0199 12-Jun R.YSGGNYR.D sp|P98179|RBM3_HUMAN 1 815.3562 0.97 58602 4522 2 815.355135 408.6854 RNA-binding protein 3 OS=Homo sapiens OX=9606 GN=RBM3 PE=1 SV=1 8.59 1467.1 - 4.59E+06 - - - -1.3258 - 1.29 0.327 - 77.9 1 2 0 -0.0011 7 0 0 0 3.62E+08 3.73E+08 - - - 2.2627 0.9929 221125_WJC_METTL3_EV_vs_WT_F05.04535.04535.2 0.136 16-Jun K.LVEEQNAEK.A "sp|Q5F1R6|DJC21_HUMAN,tr|A0A2R8Y4N5|A0A2R8Y4N5_HUMAN,tr|A0A2R8Y4Q0|A0A2R8Y4Q0_HUMAN,tr|A0A2R8Y534|A0A2R8Y534_HUMAN" 4 1058.5244 1.12 58610 4535 2 1058.523565 530.2695 DnaJ homolog subfamily C member 21 OS=Homo sapiens OX=9606 GN=DNAJC21 PE=1 SV=2 4.25 1468.6 - 360667 - - - -0.7926 - 1.02 0.248 - 86.7 1 2 0 -0.0008 9 0 0 0 1.52E+07 1.35E+07 - - - 0.9298 0.9983 221125_WJC_METTL3_EV_vs_WT_F05.04545.04545.2 0.0284 12-Sep R.C[160.03]ESLNTR[166.11].T "sp|P52732|KIF11_HUMAN,tr|A0A7I2V3A9|A0A7I2V3A9_HUMAN" 2 888.3999 3.69 58616 4545 2 888.39771 445.2072 Kinesin-like protein KIF11 OS=Homo sapiens OX=9606 GN=KIF11 PE=1 SV=2 5.99 1469.8 - 1.17E+07 - - - -2.4493 - 1.689 0.295 - 496.3 1 2 0 -0.0022 7 0 0 0 1.26E+09 3.42E+08 - - - 2.8799 0.9971 221125_WJC_METTL3_EV_vs_WT_F05.04546.04546.2 2.02 16-Sep K.LHGTVVEGR[166.11].K "sp|O43251|RFOX2_HUMAN,sp|Q9NWB1|RFOX1_HUMAN,tr|A0A6Q8PGE0|A0A6Q8PGE0_HUMAN,tr|A0A6Q8PH77|A0A6Q8PH77_HUMAN,tr|A0A286YEU2|A0A286YEU2_HUMAN,tr|A0A087X2B1|A0A087X2B1_HUMAN,tr|F8VR27|F8VR27_HUMAN,tr|B7Z1U7|B7Z1U7_HUMAN,tr|B0QYV1|B0QYV1_HUMAN,tr|A0A6Q8PHA3|A0A6Q8PHA3_HUMAN,tr|F8VZY7|F8VZY7_HUMAN,tr|B0QYY4|B0QYY4_HUMAN,tr|J3KNW3|J3KNW3_HUMAN,tr|F8VZG9|F8VZG9_HUMAN,tr|F8VRS4|F8VRS4_HUMAN,tr|A0A6Q8PFM4|A0A6Q8PFM4_HUMAN,tr|S4R469|S4R469_HUMAN,tr|A0A804HKG7|A0A804HKG7_HUMAN,tr|A0A0G2JRD1|A0A0G2JRD1_HUMAN,tr|A0A0G2JRA5|A0A0G2JRA5_HUMAN,tr|A0A804HJM2|A0A804HJM2_HUMAN,tr|I3L1D4|I3L1D4_HUMAN,tr|S4R3K7|S4R3K7_HUMAN" 23 976.5329 1.06 58617 4546 2 976.531028 489.2738 RNA binding protein fox-1 homolog 2 OS=Homo sapiens OX=9606 GN=RBFOX2 PE=1 SV=3 6.75 1469.8 - 3.33E+06 - - - -1.9672 - 1.717 0.202 - 399.1 1 2 0 -0.0019 9 0 0 0 1.15E+09 1.09E+09 - - - 2.0963 0.9967 221125_WJC_METTL3_EV_vs_WT_F05.04547.04547.2 0.149 16-Jun R.VPAQSESVR[166.11].R "sp|P50552|VASP_HUMAN,tr|K7EM16|K7EM16_HUMAN" 2 981.5119 1.53 58618 4547 2 981.511013 491.7632 Vasodilator-stimulated phosphoprotein OS=Homo sapiens OX=9606 GN=VASP PE=1 SV=3 5.97 1469.9 - 1.62E+06 - - - -0.8823 - 1.389 0.205 - 112.6 1 2 0 -0.0009 9 0 0 0 6.37E+07 4.16E+07 - - - 1.5055 0.9993 221125_WJC_METTL3_EV_vs_WT_F05.04552.04552.2 0.0436 12-Aug R.C[160.03]ESLNTR.T "sp|P52732|KIF11_HUMAN,tr|A0A7I2V3A9|A0A7I2V3A9_HUMAN" 2 878.3916 3.68 58622 4552 2 878.390179 440.2031 Kinesin-like protein KIF11 OS=Homo sapiens OX=9606 GN=KIF11 PE=1 SV=2 5.99 1470.5 - 5.11E+07 - - - -1.6359 - 1.719 0.326 - 379.2 1 2 0 -0.0014 7 0 0 0 1.25E+09 3.41E+08 - - - 3.1649 0.9876 221125_WJC_METTL3_EV_vs_WT_F05.04558.04558.2 0.271 14-Sep K.HLAAVEER[166.11].K "sp|Q8TAQ2|SMRC2_HUMAN,sp|Q92922|SMRC1_HUMAN,tr|F8VXC8|F8VXC8_HUMAN" 3 933.4907 2.77 58626 4558 2 933.487586 467.7527 SWI\SNF complex subunit SMARCC2 OS=Homo sapiens OX=9606 GN=SMARCC2 PE=1 SV=1 5.4 1471.1 - 1.12E+06 - - - -3.3884 - 1.747 0.139 - 294.7 1 2 0 -0.0032 8 0 0 0 5.26E+08 1.90E+08 - - - 1.7493 0.9995 221125_WJC_METTL3_EV_vs_WT_F05.04563.04563.2 0.000689 18-Nov R.IAGQVAAANK[136.11].K "sp|P39019|RS19_HUMAN,tr|A0A075B6E2|A0A075B6E2_HUMAN" 2 949.5436 1.18 58629 4563 2 949.541608 475.7791 40S ribosomal protein S19 OS=Homo sapiens OX=9606 GN=RPS19 PE=1 SV=2 8.75 1471.6 - 1.62E+06 - - - -2.1294 - 2.244 0.358 - 283 1 2 0 -0.002 10 0 0 0 1.13E+10 9.61E+09 - - - 3.9407 0.9986 221125_WJC_METTL3_EV_vs_WT_F05.04567.04567.2 0.0911 16-Jul K.LHGTVVEGR.K "sp|O43251|RFOX2_HUMAN,sp|Q9NWB1|RFOX1_HUMAN,tr|A0A6Q8PGE0|A0A6Q8PGE0_HUMAN,tr|A0A6Q8PH77|A0A6Q8PH77_HUMAN,tr|A0A286YEU2|A0A286YEU2_HUMAN,tr|A0A087X2B1|A0A087X2B1_HUMAN,tr|F8VR27|F8VR27_HUMAN,tr|B7Z1U7|B7Z1U7_HUMAN,tr|B0QYV1|B0QYV1_HUMAN,tr|A0A6Q8PHA3|A0A6Q8PHA3_HUMAN,tr|F8VZY7|F8VZY7_HUMAN,tr|B0QYY4|B0QYY4_HUMAN,tr|J3KNW3|J3KNW3_HUMAN,tr|F8VZG9|F8VZG9_HUMAN,tr|F8VRS4|F8VRS4_HUMAN,tr|A0A6Q8PFM4|A0A6Q8PFM4_HUMAN,tr|S4R469|S4R469_HUMAN,tr|A0A804HKG7|A0A804HKG7_HUMAN,tr|A0A0G2JRD1|A0A0G2JRD1_HUMAN,tr|A0A0G2JRA5|A0A0G2JRA5_HUMAN,tr|A0A804HJM2|A0A804HJM2_HUMAN,tr|I3L1D4|I3L1D4_HUMAN,tr|S4R3K7|S4R3K7_HUMAN" 23 966.5247 1.06 58631 4567 2 966.523992 484.2696 RNA binding protein fox-1 homolog 2 OS=Homo sapiens OX=9606 GN=RBFOX2 PE=1 SV=3 6.75 1472.2 - 2.61E+07 - - - -0.7108 - 1.431 0.278 - 206.6 1 2 0 -0.0007 9 0 0 0 1.15E+09 1.09E+09 - - - 2.1309 0.9934 221125_WJC_METTL3_EV_vs_WT_F05.04568.04568.2 2.17 12-Jul R.FTDEESR[166.11].V "sp|Q9NYF8|BCLF1_HUMAN,tr|H0YF00|H0YF00_HUMAN,tr|E9PKI6|E9PKI6_HUMAN,tr|A0A1W2PQ43|A0A1W2PQ43_HUMAN,tr|E9PK91|E9PK91_HUMAN,tr|E9PK09|E9PK09_HUMAN,tr|E9PQN2|E9PQN2_HUMAN" 7 892.3802 2.19 58632 4568 2 892.377961 447.1974 Bcl-2-associated transcription factor 1 OS=Homo sapiens OX=9606 GN=BCLAF1 PE=1 SV=2 4.14 1472.2 - 1.01E+07 - - - -2.5045 - 1.424 0.214 - 162.8 1 2 0 -0.0022 7 0 0 0 1.68E+10 7.70E+09 - - - 1.7409 0.9996 221125_WJC_METTL3_EV_vs_WT_F05.04569.04569.2 0.00115 12-Jul K.HNVIVGR.N sp|Q9UQE7|SMC3_HUMAN 1 793.4559 0.82 58633 4569 2 793.454996 397.7352 Structural maintenance of chromosomes protein 3 OS=Homo sapiens OX=9606 GN=SMC3 PE=1 SV=2 9.76 1472.3 - 1.01E+06 - - - -1.1028 - 1.508 0.442 - 142.5 1 2 0 -0.0009 7 0 0 0 3.00E+07 3.65E+07 - - - 3.6069 0.9984 221125_WJC_METTL3_EV_vs_WT_F05.04572.04572.2 1.34 12-Jul R.FTDEESR.V "sp|Q9NYF8|BCLF1_HUMAN,tr|H0YF00|H0YF00_HUMAN,tr|E9PKI6|E9PKI6_HUMAN,tr|A0A1W2PQ43|A0A1W2PQ43_HUMAN,tr|E9PK91|E9PK91_HUMAN,tr|E9PK09|E9PK09_HUMAN,tr|E9PQN2|E9PQN2_HUMAN" 7 882.3719 2.19 58634 4572 2 882.370915 442.1932 Bcl-2-associated transcription factor 1 OS=Homo sapiens OX=9606 GN=BCLAF1 PE=1 SV=2 4.14 1472.7 - 3.08E+07 - - - -1.1458 - 1.469 0.259 - 171.2 1 2 0 -0.001 7 0 0 0 1.68E+10 7.69E+09 - - - 2.1722 0.9998 221125_WJC_METTL3_EV_vs_WT_F05.04573.04573.2 0.00316 18-Nov R.IAGQVAAANK.K "sp|P39019|RS19_HUMAN,tr|A0A075B6E2|A0A075B6E2_HUMAN" 2 941.5294 1.18 58635 4573 2 941.529074 471.772 40S ribosomal protein S19 OS=Homo sapiens OX=9606 GN=RPS19 PE=1 SV=2 8.75 1472.7 - 9.32E+06 - - - -0.3781 - 2.143 0.391 - 325.5 1 2 0 -0.0004 10 0 0 0 1.13E+10 9.61E+09 - - - 4.0564 0.9994 221125_WJC_METTL3_EV_vs_WT_F05.04581.04581.2 0.0104 16-Jul K.ETAAAC[160.03]VEK[136.11].- "sp|Q15631|TSN_HUMAN,tr|E9PGT1|E9PGT1_HUMAN" 2 985.463 1.4 58640 4581 2 985.461624 493.7388 Translin OS=Homo sapiens OX=9606 GN=TSN PE=1 SV=1 4.53 1473.6 - 1.00E+06 - - - -1.3922 - 1.602 0.386 - 328 1 2 0 -0.0014 9 0 0 0 3.64E+07 2.59E+07 - - - 3.2549 0.8015 221125_WJC_METTL3_EV_vs_WT_F05.04583.04583.2 0.0966 14-May R.DVTPEATK.E "sp|Q9NQX3|GEPH_HUMAN,tr|H0YJ30|H0YJ30_HUMAN" 2 859.4287 1.22 58641 4583 2 859.4247 430.7216 Gephyrin OS=Homo sapiens OX=9606 GN=GPHN PE=1 SV=1 4.37 1473.8 - 771247 - - - -4.6694 - 1.083 0.193 - 76.9 8 2 0 -0.004 8 0 0 0 2.11E+07 1.74E+07 - - - 0.3023 0.9988 221125_WJC_METTL3_EV_vs_WT_F05.04585.04585.2 0.0222 16-Sep K.GTGLNPNAK.V "sp|Q71RC2|LARP4_HUMAN,tr|F8VY40|F8VY40_HUMAN,tr|F8VNV1|F8VNV1_HUMAN,tr|F8W1Z5|F8W1Z5_HUMAN" 4 870.4559 1.6 58642 4585 2 870.454406 436.2352 La-related protein 4 OS=Homo sapiens OX=9606 GN=LARP4 PE=1 SV=3 8.75 1474 - 1.17E+06 - - - -1.7508 - 1.757 0.281 - 281.1 1 2 0 -0.0015 9 0 0 0 2.79E+08 1.74E+08 - - - 2.7465 0.9525 221125_WJC_METTL3_EV_vs_WT_F05.04590.04590.2 1.54 12-Jul R.QFQNAPK.E sp|O75131|CPNE3_HUMAN 1 831.4239 0.19 58645 4590 2 831.422117 416.7192 Copine-3 OS=Homo sapiens OX=9606 GN=CPNE3 PE=1 SV=1 8.75 1474.6 - 1.49E+06 - - - -2.1469 - 1.052 0.128 - 179 1 2 0 -0.0018 7 0 0 0 4.08E+07 2.14E+08 - - - 0.1465 0.8606 221125_WJC_METTL3_EV_vs_WT_F05.04597.04597.2 0.327 12-Jun K.EYEEEER[166.11].K "sp|Q16543|CDC37_HUMAN,tr|K7EQA9|K7EQA9_HUMAN,tr|K7EL68|K7EL68_HUMAN,tr|K7EKQ2|K7EKQ2_HUMAN,tr|K7EIU0|K7EIU0_HUMAN" 5 992.3962 0.91 58649 4597 2 992.392239 497.2054 Hsp90 co-chaperone Cdc37 OS=Homo sapiens OX=9606 GN=CDC37 PE=1 SV=1 3.98 1475.4 - 724348 - - - -4.0317 - 1.261 0.068 - 171.4 1 2 0 -0.004 7 0 0 0 1.19E+07 1.31E+07 - - - 0.2768 0.8857 221125_WJC_METTL3_EV_vs_WT_F05.04598.04598.2 4.54 12-Jun K.EYEEEER.K "sp|Q16543|CDC37_HUMAN,tr|K7EQA9|K7EQA9_HUMAN,tr|K7EL68|K7EL68_HUMAN,tr|K7EKQ2|K7EKQ2_HUMAN,tr|K7EIU0|K7EIU0_HUMAN" 5 982.388 0.9 58650 4598 2 982.390242 492.2013 Hsp90 co-chaperone Cdc37 OS=Homo sapiens OX=9606 GN=CDC37 PE=1 SV=1 3.98 1475.6 - 1.59E+06 - - - 2.3127 - 0.987 0.089 - 130.3 1 2 0 0.0023 7 0 0 0 1.19E+07 1.32E+07 - - - -0.3438 0.9663 221125_WJC_METTL3_EV_vs_WT_F05.04606.04606.2 0.691 16-Aug K.LPQTSDDEK[136.11].K sp|Q9GZT3|SLIRP_HUMAN 1 1039.4913 1.45 58654 4606 2 1039.486355 520.7529 "SRA stem-loop-interacting RNA-binding protein, mitochondrial OS=Homo sapiens OX=9606 GN=SLIRP PE=1 SV=1" 4.03 1476.3 - 3.88E+06 - - - -4.7754 - 1.502 0.225 - 81.8 2 2 0 -0.005 9 0 0 0 4.17E+08 2.89E+08 - - - 1.7437 0.9992 221125_WJC_METTL3_EV_vs_WT_F05.04609.04609.2 0.0238 12-Nov R.K[136.11]GVITVK[136.11].D "sp|P10809|CH60_HUMAN,tr|A0A7I2V599|A0A7I2V599_HUMAN,tr|E7EXB4|E7EXB4_HUMAN,tr|A0A7I2YQ71|A0A7I2YQ71_HUMAN,tr|A0A7I2V5M1|A0A7I2V5M1_HUMAN,tr|A0A7I2V5K3|A0A7I2V5K3_HUMAN,tr|A0A7I2V369|A0A7I2V369_HUMAN" 7 759.5189 0.001 58655 4609 2 759.516939 380.7667 "60 kDa heat shock protein, mitochondrial OS=Homo sapiens OX=9606 GN=HSPD1 PE=1 SV=2" 10 1476.7 - 1.02E+07 - - - -2.6148 - 2.233 0.313 - 436.1 1 2 0 -0.002 7 0 0 0 0.00E+00 1.19E+10 - - - 3.8976 0.9878 221125_WJC_METTL3_EV_vs_WT_F05.04615.04615.2 0.0603 16-Jul R.SAVPPGADK[136.11].K "sp|P46783|RS10_HUMAN,tr|F6U211|F6U211_HUMAN,tr|A0A1W2PQS6|A0A1W2PQS6_HUMAN,tr|A0A2R8YFH6|A0A2R8YFH6_HUMAN,tr|A0A2R8Y7H1|A0A2R8Y7H1_HUMAN,tr|S4R435|S4R435_HUMAN" 6 848.4483 1.35 58659 4615 2 848.445329 425.2314 40S ribosomal protein S10 OS=Homo sapiens OX=9606 GN=RPS10 PE=1 SV=1 5.55 1477.3 - 1.09E+07 - - - -3.5394 - 1.222 0.302 - 150.8 1 2 0 -0.003 9 0 0 0 7.15E+08 5.29E+08 - - - 1.8507 0.9973 221125_WJC_METTL3_EV_vs_WT_F05.04622.04622.2 0.0048 14-Nov K.HLAAVEER.K "sp|Q8TAQ2|SMRC2_HUMAN,sp|Q92922|SMRC1_HUMAN,tr|F8VXC8|F8VXC8_HUMAN" 3 923.4825 2.77 58662 4622 2 923.479705 462.7485 SWI\SNF complex subunit SMARCC2 OS=Homo sapiens OX=9606 GN=SMARCC2 PE=1 SV=1 5.4 1478.2 - 8.01E+06 - - - -3.0038 - 1.949 0.241 - 508 1 2 0 -0.0028 8 0 0 0 5.27E+08 1.90E+08 - - - 2.8328 0.9971 221125_WJC_METTL3_EV_vs_WT_F05.04628.04628.2 0.216 12-Jul R.FSEAEQR.C sp|P33993|MCM7_HUMAN 1 865.393 1.01 58665 4628 2 865.391221 433.7038 DNA replication licensing factor MCM7 OS=Homo sapiens OX=9606 GN=MCM7 PE=1 SV=4 4.53 1478.9 - 3.73E+06 - - - -2.0511 - 1.492 0.249 - 121.5 1 2 0 -0.0018 7 0 0 0 8.98E+07 8.86E+07 - - - 2.1474 0.9875 221125_WJC_METTL3_EV_vs_WT_F05.04630.04630.2 0.0431 16-Jul R.ETGITANEK[136.11].C "sp|Q9HCE5|MET14_HUMAN,tr|D6RBL4|D6RBL4_HUMAN" 2 969.4858 0.19 58666 4630 2 969.48234 485.7502 N6-adenosine-methyltransferase non-catalytic subunit OS=Homo sapiens OX=9606 GN=METTL14 PE=1 SV=2 4.53 1479.1 - 5.67E+06 - - - -3.6102 - 1.354 0.265 - 171.2 1 2 0 -0.0035 9 0 0 0 6.10E+07 3.15E+08 - - - 1.874 0.9977 221125_WJC_METTL3_EV_vs_WT_F05.04639.04639.2 0.437 14-Sep R.TDAISEEK.L "sp|Q9NR31|SAR1A_HUMAN,tr|H0Y5E8|H0Y5E8_HUMAN" 2 891.4185 1.08 58670 4639 2 891.416253 446.7165 GTP-binding protein SAR1a OS=Homo sapiens OX=9606 GN=SAR1A PE=1 SV=1 4.14 1480.2 - 1.16E+08 - - - -2.5678 - 1.951 0.223 - 307.3 1 2 0 -0.0023 8 0 0 0 2.30E+09 2.13E+09 - - - 2.703 0.8907 221125_WJC_METTL3_EV_vs_WT_F05.04640.04640.2 1.53 12-Aug K.VR[166.11]ELVDK[136.11].A sp|Q14677|EPN4_HUMAN 1 875.5195 1.34 58671 4640 2 875.518558 438.767 Clathrin interactor 1 OS=Homo sapiens OX=9606 GN=CLINT1 PE=1 SV=1 6.04 1480.3 - 4.96E+06 - - - -1.1182 - 1.492 0.056 - 208.8 1 2 1 -0.001 7 0 0 0 1.15E+08 8.61E+07 - - - 0.7221 0.9994 221125_WJC_METTL3_EV_vs_WT_F05.04641.04641.2 0.000374 16-Nov K.SPVAVQSTK[136.11].V "sp|Q13011|ECH1_HUMAN,tr|M0R248|M0R248_HUMAN" 2 923.5167 1.84 58672 4641 2 923.514611 462.7656 "Delta(3,5)-Delta(2,4)-dienoyl-CoA isomerase, mitochondrial OS=Homo sapiens OX=9606 GN=ECH1 PE=1 SV=2" 8.47 1480.4 - 1.95E+06 - - - -2.3118 - 2.044 0.392 - 514.4 1 2 0 -0.0021 9 0 0 0 1.01E+08 5.48E+07 - - - 4.0039 0.9975 221125_WJC_METTL3_EV_vs_WT_F05.04642.04642.2 0.00239 16-Aug R.LTC[160.03]EEEEEK[136.11].L "sp|P51531|SMCA2_HUMAN,sp|P51532|SMCA4_HUMAN,tr|A0A2R8Y5K3|A0A2R8Y5K3_HUMAN,tr|A0A2R8Y7S2|A0A2R8Y7S2_HUMAN,tr|A0A2R8Y7F3|A0A2R8Y7F3_HUMAN,tr|A0A2R8YGG3|A0A2R8YGG3_HUMAN,tr|A0A0U1RQZ9|A0A0U1RQZ9_HUMAN,tr|A0A2R8Y523|A0A2R8Y523_HUMAN,tr|A0A2R8Y6V2|A0A2R8Y6V2_HUMAN,tr|A0A0U1RRG6|A0A0U1RRG6_HUMAN,tr|Q9HBD4|Q9HBD4_HUMAN,tr|K7EQF0|K7EQF0_HUMAN,tr|A0A2R8Y440|A0A2R8Y440_HUMAN,tr|F6VDE0|F6VDE0_HUMAN,tr|A0A2R8YFK5|A0A2R8YFK5_HUMAN,tr|A0A2R8YDA1|A0A2R8YDA1_HUMAN,tr|A0A2R8Y7Y7|A0A2R8Y7Y7_HUMAN,tr|A0A2R8YF58|A0A2R8YF58_HUMAN,tr|A0A2R8Y526|A0A2R8Y526_HUMAN,tr|K7EP28|K7EP28_HUMAN,tr|A0A2R8YG32|A0A2R8YG32_HUMAN,tr|A0A2R8Y6N0|A0A2R8Y6N0_HUMAN,tr|A0A2R8YF80|A0A2R8YF80_HUMAN,tr|A0A2R8Y4P4|A0A2R8Y4P4_HUMAN,tr|A0A2R8Y4C5|A0A2R8Y4C5_HUMAN" 25 1173.4951 0.74 58673 4642 2 1173.4908 587.7548 Probable global transcription activator SNF2L2 OS=Homo sapiens OX=9606 GN=SMARCA2 PE=1 SV=2 3.98 1480.5 - 679873 - - - -3.6506 - 1.691 0.385 - 231.5 1 2 0 -0.0043 9 0 0 0 6.13E+06 8.31E+06 - - - 3.403 0.979 221125_WJC_METTL3_EV_vs_WT_F05.04648.04648.2 1.61 12-Aug K.SLSPQDR.A "sp|P17480|UBF1_HUMAN,tr|E9PKP7|E9PKP7_HUMAN" 2 801.3981 1.57 58677 4648 2 801.396547 401.7063 Nucleolar transcription factor 1 OS=Homo sapiens OX=9606 GN=UBTF PE=1 SV=1 5.55 1481.2 - 1.66E+06 - - - -1.9142 - 1.248 0.115 - 287 1 2 0 -0.0015 7 0 0 0 9.59E+07 6.10E+07 - - - 0.5919 0.9984 221125_WJC_METTL3_EV_vs_WT_F05.04651.04651.2 0.0463 14-Jul R.NTEEEGLK[136.11].Y "sp|Q9NYF8|BCLF1_HUMAN,tr|E9PKI6|E9PKI6_HUMAN,tr|A0A1W2PQ43|A0A1W2PQ43_HUMAN,tr|E9PK91|E9PK91_HUMAN,tr|E9PK09|E9PK09_HUMAN,tr|E9PQN2|E9PQN2_HUMAN" 6 926.4436 2.32 58678 4651 2 926.441239 464.2291 Bcl-2-associated transcription factor 1 OS=Homo sapiens OX=9606 GN=BCLAF1 PE=1 SV=2 4.25 1481.6 - 4.21E+06 - - - -2.5927 - 1.632 0.342 - 274.3 1 2 0 -0.0024 8 0 0 0 2.03E+10 8.76E+09 - - - 3.0435 0.9986 221125_WJC_METTL3_EV_vs_WT_F05.04664.04664.2 0.000792 12-Jun K.DC[160.03]EAEVR.A "sp|P30153|2AAA_HUMAN,sp|P30154|2AAB_HUMAN,tr|C9J9C1|C9J9C1_HUMAN,tr|H0YDG7|H0YDG7_HUMAN,tr|B3KQV6|B3KQV6_HUMAN" 5 877.36 0.67 58685 4664 2 877.357612 439.6873 Serine\threonine-protein phosphatase 2A 65 kDa regulatory subunit A alpha isoform OS=Homo sapiens OX=9606 GN=PPP2R1A PE=1 SV=4 4.14 1483.1 - 3.13E+06 - - - -2.7001 - 1.41 0.431 - 231.7 1 2 0 -0.0024 7 0 0 0 6.13E+07 9.14E+07 - - - 3.3123 0.9762 221125_WJC_METTL3_EV_vs_WT_F05.04670.04670.2 0.298 14-Jul K.GHLSGLAK.R "sp|Q15149|PLEC_HUMAN,tr|H0YDN1|H0YDN1_HUMAN" 2 781.4446 1.25 58689 4670 2 781.441732 391.7296 Plectin OS=Homo sapiens OX=9606 GN=PLEC PE=1 SV=3 8.76 1483.7 - 929243 - - - -3.7175 - 1.503 0.157 - 179.4 1 2 0 -0.0029 8 0 0 0 2.14E+07 1.71E+07 - - - 1.4286 0.9321 221125_WJC_METTL3_EV_vs_WT_F05.04674.04674.2 0.362 14-Jul K.VPEPGC[160.03]TK.V "sp|Q9UBC9|SPRR3_HUMAN,tr|B1AN48|B1AN48_HUMAN" 2 886.4219 12.72 58691 4674 2 886.420347 444.2182 Small proline-rich protein 3 OS=Homo sapiens OX=9606 GN=SPRR3 PE=1 SV=2 5.97 1484.3 - 5.76E+06 - - - -1.699 - 1.128 0.06 - 172.3 2 2 0 -0.0015 8 0 0 0 4.81E+08 3.78E+07 - - - -0.2875 0.9998 221125_WJC_METTL3_EV_vs_WT_F05.04676.04676.2 0.000372 16-Dec K.NAESNAELK.G "sp|P18621|RL17_HUMAN,tr|A0A087WWH0|A0A087WWH0_HUMAN,tr|J3QS96|J3QS96_HUMAN,tr|J3QLC8|J3QLC8_HUMAN,tr|J3QQT2|J3QQT2_HUMAN,tr|A0A0A0MRF8|A0A0A0MRF8_HUMAN,tr|J3KRB3|J3KRB3_HUMAN,tr|J3KRX5|J3KRX5_HUMAN,tr|A0A087WXM6|A0A087WXM6_HUMAN,tr|A0A0A6YYL6|A0A0A6YYL6_HUMAN" 10 974.4669 1.1 58692 4676 2 974.46511 488.2407 60S ribosomal protein L17 OS=Homo sapiens OX=9606 GN=RPL17 PE=1 SV=3 4.53 1484.5 - 8.25E+06 - - - -1.8256 - 2.395 0.508 - 700.4 1 2 0 -0.0018 9 0 0 0 1.63E+09 1.49E+09 - - - 5.3193 0.8425 221125_WJC_METTL3_EV_vs_WT_F05.04680.04680.2 1.2 12-May K.DEDISQK.D sp|P53701|CCHL_HUMAN 1 833.3767 5.23 58695 4680 2 833.37451 417.6956 Holocytochrome c-type synthase OS=Homo sapiens OX=9606 GN=HCCS PE=1 SV=1 4.03 1484.8 - 1.54E+06 - - - -2.6003 - 1.077 0.101 - 77.8 13 2 0 -0.0022 7 0 0 0 9.14E+07 1.75E+07 - - - -0.4763 0.7894 221125_WJC_METTL3_EV_vs_WT_F05.04693.04693.2 0.67 14-Jul E.PDDEEGLK[136.11].H "sp|Q6Y7W6|GGYF2_HUMAN,tr|A0A7I2V3H7|A0A7I2V3H7_HUMAN,tr|I1E4Y6|I1E4Y6_HUMAN,tr|A0A7I2V516|A0A7I2V516_HUMAN,tr|A0A7I2V3H0|A0A7I2V3H0_HUMAN,tr|C9JHW1|C9JHW1_HUMAN,tr|A0A7I2V361|A0A7I2V361_HUMAN,tr|E7ESB6|E7ESB6_HUMAN" 8 909.4171 19.26 58704 4693 2 909.417289 455.7158 GRB10-interacting GYF protein 2 OS=Homo sapiens OX=9606 GN=GIGYF2 PE=1 SV=1 3.92 1486.3 - 3.71E+06 - - - 0.2166 - 1.336 0.175 - 246.6 1 1 0 0.0002 8 0 0 0 1.94E+09 1.00E+08 - - - 1.2071 0.9721 221125_WJC_METTL3_EV_vs_WT_F05.04699.04699.2 0.0415 16-Oct T.FENSADADR.A "sp|O43251|RFOX2_HUMAN,sp|Q9NWB1|RFOX1_HUMAN,tr|A0A6Q8PGE0|A0A6Q8PGE0_HUMAN,tr|A0A6Q8PH77|A0A6Q8PH77_HUMAN,tr|A0A286YEU2|A0A286YEU2_HUMAN,tr|A0A087X2B1|A0A087X2B1_HUMAN,tr|F8VR27|F8VR27_HUMAN,tr|B7Z1U7|B7Z1U7_HUMAN,tr|B0QYV1|B0QYV1_HUMAN,tr|A0A6Q8PHA3|A0A6Q8PHA3_HUMAN,tr|F8VZY7|F8VZY7_HUMAN,tr|B0QYY4|B0QYY4_HUMAN,tr|J3KNW3|J3KNW3_HUMAN,tr|F8VZG9|F8VZG9_HUMAN,tr|F8VRS4|F8VRS4_HUMAN,tr|A0A6Q8PFM4|A0A6Q8PFM4_HUMAN,tr|S4R469|S4R469_HUMAN,tr|A0A804HKG7|A0A804HKG7_HUMAN,tr|A0A0G2JRD1|A0A0G2JRD1_HUMAN,tr|A0A0G2JRA5|A0A0G2JRA5_HUMAN,tr|A0A804HJM2|A0A804HJM2_HUMAN,tr|I3L1D4|I3L1D4_HUMAN,tr|B0QYY7|B0QYY7_HUMAN,tr|A0A0G2JSB3|A0A0G2JSB3_HUMAN,tr|S4R3K7|S4R3K7_HUMAN" 25 1023.4258 1.66 58706 4699 2 1023.423688 512.7202 RNA binding protein fox-1 homolog 2 OS=Homo sapiens OX=9606 GN=RBFOX2 PE=1 SV=3 4.03 1487.1 - 1.90E+06 - - - -2.0168 - 1.906 0.414 - 301.5 1 1 0 -0.0021 9 0 0 0 6.86E+07 4.12E+07 - - - 3.9642 0.9766 221125_WJC_METTL3_EV_vs_WT_F05.04701.04701.2 0.000626 16-Oct T.FENSADADR[166.11].A "sp|O43251|RFOX2_HUMAN,sp|Q9NWB1|RFOX1_HUMAN,tr|A0A6Q8PGE0|A0A6Q8PGE0_HUMAN,tr|A0A6Q8PH77|A0A6Q8PH77_HUMAN,tr|A0A286YEU2|A0A286YEU2_HUMAN,tr|A0A087X2B1|A0A087X2B1_HUMAN,tr|F8VR27|F8VR27_HUMAN,tr|B7Z1U7|B7Z1U7_HUMAN,tr|B0QYV1|B0QYV1_HUMAN,tr|A0A6Q8PHA3|A0A6Q8PHA3_HUMAN,tr|F8VZY7|F8VZY7_HUMAN,tr|B0QYY4|B0QYY4_HUMAN,tr|J3KNW3|J3KNW3_HUMAN,tr|F8VZG9|F8VZG9_HUMAN,tr|F8VRS4|F8VRS4_HUMAN,tr|A0A6Q8PFM4|A0A6Q8PFM4_HUMAN,tr|S4R469|S4R469_HUMAN,tr|A0A804HKG7|A0A804HKG7_HUMAN,tr|A0A0G2JRD1|A0A0G2JRD1_HUMAN,tr|A0A0G2JRA5|A0A0G2JRA5_HUMAN,tr|A0A804HJM2|A0A804HJM2_HUMAN,tr|I3L1D4|I3L1D4_HUMAN,tr|B0QYY7|B0QYY7_HUMAN,tr|A0A0G2JSB3|A0A0G2JSB3_HUMAN,tr|S4R3K7|S4R3K7_HUMAN" 25 1033.434 1.66 58708 4701 2 1033.431375 517.7243 RNA binding protein fox-1 homolog 2 OS=Homo sapiens OX=9606 GN=RBFOX2 PE=1 SV=3 4.03 1487.4 - 1.82E+06 - - - -2.5614 - 2.068 0.499 - 301.2 1 1 0 -0.0026 9 0 0 0 6.86E+07 4.12E+07 - - - 4.8278 0.9677 221125_WJC_METTL3_EV_vs_WT_F05.04717.04717.2 9.56 16-Jul K.ALVATPGK[136.11]K[136.11].G "sp|P19338|NUCL_HUMAN,tr|A0A7I2V506|A0A7I2V506_HUMAN,tr|A0A7I2V699|A0A7I2V699_HUMAN,tr|A0A7I2V2U7|A0A7I2V2U7_HUMAN,tr|A0A7I2V3F3|A0A7I2V3F3_HUMAN,tr|A0A7I2V428|A0A7I2V428_HUMAN,tr|A0A7I2V349|A0A7I2V349_HUMAN,tr|H7BY16|H7BY16_HUMAN,tr|A0A7I2V5M5|A0A7I2V5M5_HUMAN,tr|A0A7I2V2S8|A0A7I2V2S8_HUMAN,tr|C9JLB1|C9JLB1_HUMAN" 11 899.5775 0.89 58714 4717 2 899.576255 450.796 Nucleolin OS=Homo sapiens OX=9606 GN=NCL PE=1 SV=3 10 1489.4 - 8.32E+06 - - - -1.3862 - 1.157 0.084 - 157.6 1 2 0 -0.0012 9 0 0 0 1.32E+08 1.48E+08 - - - 0.0829 0.9582 221125_WJC_METTL3_EV_vs_WT_F05.04726.04726.2 0.419 16-Jul K.ALVATPGKK.G "sp|P19338|NUCL_HUMAN,tr|A0A7I2V506|A0A7I2V506_HUMAN,tr|A0A7I2V699|A0A7I2V699_HUMAN,tr|A0A7I2V2U7|A0A7I2V2U7_HUMAN,tr|A0A7I2V3F3|A0A7I2V3F3_HUMAN,tr|A0A7I2V428|A0A7I2V428_HUMAN,tr|A0A7I2V349|A0A7I2V349_HUMAN,tr|H7BY16|H7BY16_HUMAN,tr|A0A7I2V5M5|A0A7I2V5M5_HUMAN,tr|A0A7I2V2S8|A0A7I2V2S8_HUMAN,tr|C9JLB1|C9JLB1_HUMAN" 11 883.5491 0.89 58717 4726 2 883.546892 442.7818 Nucleolin OS=Homo sapiens OX=9606 GN=NCL PE=1 SV=3 10 1490.6 - 7.28E+06 - - - -2.5013 - 1.311 0.078 - 191.1 1 2 0 -0.0022 9 0 0 0 1.32E+08 1.48E+08 - - - 0.3998 0.9572 221125_WJC_METTL3_EV_vs_WT_F05.04729.04729.2 0.604 16-Jul R.SAVPPGADK.K "sp|P46783|RS10_HUMAN,tr|F6U211|F6U211_HUMAN,tr|A0A1W2PQS6|A0A1W2PQS6_HUMAN,tr|A0A2R8YFH6|A0A2R8YFH6_HUMAN,tr|A0A2R8Y7H1|A0A2R8Y7H1_HUMAN,tr|S4R435|S4R435_HUMAN" 6 840.4341 1.22 58719 4729 2 840.430332 421.2243 40S ribosomal protein S10 OS=Homo sapiens OX=9606 GN=RPS10 PE=1 SV=1 5.55 1490.9 - 1.03E+07 - - - -4.5215 - 1.279 0.225 - 137.3 1 2 0 -0.0038 9 0 0 0 5.20E+08 4.25E+08 - - - 1.4136 0.9828 221125_WJC_METTL3_EV_vs_WT_F05.04731.04731.2 6.76E-05 14-Sep L.TAQPATYR.A sp|Q96PK6|RBM14_HUMAN 1 906.4559 1.66 58720 4731 2 906.457087 454.2352 RNA-binding protein 14 OS=Homo sapiens OX=9606 GN=RBM14 PE=1 SV=2 8.41 1491.1 - 1.39E+07 - - - 1.2764 - 1.653 0.485 - 333.7 1 1 0 0.0012 8 0 0 0 4.01E+08 2.42E+08 - - - 4.1386 0.9938 221125_WJC_METTL3_EV_vs_WT_F05.04732.04732.2 0.0396 14-Jul K.QGTEIDGR[166.11].S "sp|P19338|NUCL_HUMAN,tr|A0A7I2V506|A0A7I2V506_HUMAN,tr|A0A7I2V2U7|A0A7I2V2U7_HUMAN,tr|A0A7I2V3F3|A0A7I2V3F3_HUMAN,tr|A0A7I2V428|A0A7I2V428_HUMAN,tr|A0A7I2V349|A0A7I2V349_HUMAN,tr|H7BY16|H7BY16_HUMAN,tr|A0A7I2V5M5|A0A7I2V5M5_HUMAN,tr|C9JLB1|C9JLB1_HUMAN" 9 884.4227 0.79 58721 4732 2 884.42033 443.2186 Nucleolin OS=Homo sapiens OX=9606 GN=NCL PE=1 SV=3 4.37 1491.1 - 1.01E+07 - - - -2.7125 - 1.558 0.208 - 250.5 1 2 0 -0.0024 8 0 0 0 8.19E+08 1.04E+09 - - - 1.9138 0.9969 221125_WJC_METTL3_EV_vs_WT_F05.04738.04738.2 0.24 16-Sep R.AQQEAPAVR[166.11].K sp|Q9NUL7|DDX28_HUMAN 1 978.5122 0.77 58724 4738 2 978.510447 490.2634 Probable ATP-dependent RNA helicase DDX28 OS=Homo sapiens OX=9606 GN=DDX28 PE=1 SV=2 6.05 1491.9 - 3.17E+06 - - - -1.8048 - 1.68 0.192 - 167.5 1 2 0 -0.0018 9 0 0 0 5.14E+07 6.72E+07 - - - 1.9595 0.9633 221125_WJC_METTL3_EV_vs_WT_F05.04742.04742.2 0.000405 14-Sep L.TAQPATYR[166.11].A sp|Q96PK6|RBM14_HUMAN 1 916.4642 1.58 58726 4742 2 916.462231 459.2394 RNA-binding protein 14 OS=Homo sapiens OX=9606 GN=RBM14 PE=1 SV=2 8.41 1492.5 - 1.59E+07 - - - -2.1485 - 1.639 0.433 - 342.9 1 1 0 -0.002 8 0 0 0 4.02E+08 2.54E+08 - - - 3.7287 0.9933 221125_WJC_METTL3_EV_vs_WT_F05.04743.04743.2 0.0361 12-Aug R.C[160.03]DSADLR.H "sp|Q9NYF8|BCLF1_HUMAN,tr|E9PKI6|E9PKI6_HUMAN,tr|E9PK91|E9PK91_HUMAN,tr|E9PK09|E9PK09_HUMAN,tr|E9PQN2|E9PQN2_HUMAN" 5 835.3494 2.03 58727 4743 2 835.346503 418.682 Bcl-2-associated transcription factor 1 OS=Homo sapiens OX=9606 GN=BCLAF1 PE=1 SV=2 4.21 1492.5 - 7.02E+06 - - - -3.4884 - 1.484 0.275 - 337 1 2 0 -0.0029 7 0 0 0 1.79E+09 8.79E+08 - - - 2.322 0.9838 221125_WJC_METTL3_EV_vs_WT_F05.04744.04744.2 0.116 18-Dec R.ADAEEEAATR[166.11].L sp|Q13409|DC1I2_HUMAN 1 1071.4708 0.77 58728 4744 2 1071.462584 536.7427 Cytoplasmic dynein 1 intermediate chain 2 OS=Homo sapiens OX=9606 GN=DYNC1I2 PE=1 SV=3 4 1492.6 - 983275 - - - -7.6698 - 2.64 0.376 - 887.4 1 2 0 -0.0082 10 0 0 0 1.86E+07 2.42E+07 - - - 4.5253 0.9981 221125_WJC_METTL3_EV_vs_WT_F05.04749.04749.2 0.0137 12-Aug R.C[160.03]DSADLR[166.11].H "sp|Q9NYF8|BCLF1_HUMAN,tr|E9PKI6|E9PKI6_HUMAN,tr|E9PK91|E9PK91_HUMAN,tr|E9PK09|E9PK09_HUMAN,tr|E9PQN2|E9PQN2_HUMAN" 5 845.3577 2.03 58731 4749 2 845.355876 423.6861 Bcl-2-associated transcription factor 1 OS=Homo sapiens OX=9606 GN=BCLAF1 PE=1 SV=2 4.21 1493.1 - 9.00E+06 - - - -2.1423 - 1.588 0.282 - 332.6 1 2 0 -0.0018 7 0 0 0 1.79E+09 8.79E+08 - - - 2.5887 0.9803 221125_WJC_METTL3_EV_vs_WT_F05.04752.04752.2 0.0404 12-Aug R.VGQTIER.M "sp|P52272|HNRPM_HUMAN,tr|M0R2I7|M0R2I7_HUMAN,tr|A0A087X0X3|A0A087X0X3_HUMAN,tr|M0QZM1|M0QZM1_HUMAN" 4 801.4345 1.07 58732 4752 2 801.430765 401.7245 Heterogeneous nuclear ribonucleoprotein M OS=Homo sapiens OX=9606 GN=HNRNPM PE=1 SV=3 5.97 1493.5 - 3.36E+06 - - - -4.6192 - 1.632 0.204 - 219.1 1 2 0 -0.0037 7 0 0 0 4.80E+07 4.50E+07 - - - 2.0986 0.9994 221125_WJC_METTL3_EV_vs_WT_F05.04754.04754.2 0.174 18-Oct K.IAEVGAGGNK[136.11].S "sp|Q00577|PURA_HUMAN,tr|A0A494C0H6|A0A494C0H6_HUMAN" 2 922.4963 1.35 58734 4754 2 922.497122 462.2554 Transcriptional activator protein Pur-alpha OS=Homo sapiens OX=9606 GN=PURA PE=1 SV=2 6 1493.8 - 2.60E+06 - - - 0.8423 - 2.067 0.268 - 221.1 1 2 0 0.0008 10 0 0 0 6.83E+07 5.07E+07 - - - 3.047 0.9756 221125_WJC_METTL3_EV_vs_WT_F05.04755.04755.2 0.211 16-Sep R.VGPNAPEEK.K "sp|Q06787|FMR1_HUMAN,tr|A8MQB8|A8MQB8_HUMAN,tr|A0A087WXI3|A0A087WXI3_HUMAN,tr|G3V0J0|G3V0J0_HUMAN" 4 939.4662 2 58735 4755 2 939.462892 470.7404 Synaptic functional regulator FMR1 OS=Homo sapiens OX=9606 GN=FMR1 PE=1 SV=1 4.53 1493.9 - 2.29E+06 - - - -3.4796 - 1.468 0.153 - 130.3 1 2 0 -0.0033 9 0 0 0 4.70E+08 2.34E+08 - - - 1.2807 0.9969 221125_WJC_METTL3_EV_vs_WT_F05.04757.04757.2 0.162 12-Jul R.EAQVNVR.M "sp|Q9Y2W1|TR150_HUMAN,tr|A0A3B3ITZ9|A0A3B3ITZ9_HUMAN" 2 814.4297 2.53 58736 4757 2 814.42885 408.2221 Thyroid hormone receptor-associated protein 3 OS=Homo sapiens OX=9606 GN=THRAP3 PE=1 SV=2 6.1 1494.1 - 2.11E+09 - - - -1.0633 - 1.325 0.227 - 343.2 1 2 0 -0.0009 7 0 0 0 4.08E+10 1.61E+10 - - - 1.609 0.9983 221125_WJC_METTL3_EV_vs_WT_F05.04760.04760.2 0.00966 14-Sep K.TTQEQLAR.E "sp|Q9P2E9|RRBP1_HUMAN,tr|A0A087WU26|A0A087WU26_HUMAN,tr|A0A087WVV2|A0A087WVV2_HUMAN,tr|F8W7S5|F8W7S5_HUMAN" 4 945.488 0.7 58738 4760 2 945.485053 473.7513 Ribosome-binding protein 1 OS=Homo sapiens OX=9606 GN=RRBP1 PE=1 SV=5 5.66 1494.4 - 6.62E+06 - - - -3.0735 - 1.879 0.325 - 420.2 1 2 0 -0.0029 8 0 0 0 6.11E+07 8.75E+07 - - - 3.3428 0.9987 221125_WJC_METTL3_EV_vs_WT_F05.04762.04762.2 0.02 16-Aug K.EVVESEGER.K "sp|Q8TAQ2|SMRC2_HUMAN,tr|F8VXC8|F8VXC8_HUMAN" 2 1032.4724 2.93 58740 4762 2 1032.472894 517.2435 SWI\SNF complex subunit SMARCC2 OS=Homo sapiens OX=9606 GN=SMARCC2 PE=1 SV=1 4.09 1494.6 - 2.37E+06 - - - 0.5095 - 1.405 0.3 - 211.7 1 2 0 0.0005 9 0 0 0 3.23E+07 1.10E+07 - - - 2.2404 0.9982 221125_WJC_METTL3_EV_vs_WT_F05.04766.04766.2 0.137 18-Nov K.IAEVGAGGNK.S "sp|Q00577|PURA_HUMAN,tr|A0A494C0H6|A0A494C0H6_HUMAN" 2 914.4821 1.36 58742 4766 2 914.479359 458.2483 Transcriptional activator protein Pur-alpha OS=Homo sapiens OX=9606 GN=PURA PE=1 SV=2 6 1495 - 9.83E+06 - - - -3.0465 - 2.288 0.259 - 361.8 1 2 0 -0.0028 10 0 0 0 6.88E+07 5.07E+07 - - - 3.2634 0.9142 221125_WJC_METTL3_EV_vs_WT_F05.04767.04767.2 3.37E-06 22-Dec T.TAAPAAAAAPAK.V "sp|Q8NHW5|RLA0L_HUMAN,sp|P05388|RLA0_HUMAN,tr|F8VWS0|F8VWS0_HUMAN,tr|F8W1K8|F8W1K8_HUMAN" 4 1009.5556 0.25 58743 4767 2 1009.551518 505.7851 60S acidic ribosomal protein P0-like OS=Homo sapiens OX=9606 GN=RPLP0P6 PE=5 SV=1 8.41 1495.1 - 1.26E+06 - - - -4.0869 - 2.054 0.473 - 483.8 1 1 0 -0.0041 12 0 0 0 1.08E+07 4.33E+07 - - - 4.4272 0.9951 221125_WJC_METTL3_EV_vs_WT_F05.04768.04768.2 0.142 12-Jun K.NELDQC[160.03]K.S "sp|P52732|KIF11_HUMAN,tr|A0A7I2YQY4|A0A7I2YQY4_HUMAN,tr|A0A7I2V3A9|A0A7I2V3A9_HUMAN,tr|A0A7I2V3V3|A0A7I2V3V3_HUMAN" 4 905.3913 4.95 58744 4768 2 905.388786 453.7029 Kinesin-like protein KIF11 OS=Homo sapiens OX=9606 GN=KIF11 PE=1 SV=2 4.37 1495.2 - 1.08E+07 - - - -2.7557 - 1.331 0.296 - 195.9 1 2 0 -0.0025 7 0 0 0 1.08E+08 2.18E+07 - - - 2.1325 0.9975 221125_WJC_METTL3_EV_vs_WT_F05.04769.04769.2 0.0151 14-Aug K.SQQALVQK.R "sp|P24539|AT5F1_HUMAN,tr|Q5QNZ2|Q5QNZ2_HUMAN" 2 900.5029 0.84 58745 4769 2 900.500663 451.2587 "ATP synthase F(0) complex subunit B1, mitochondrial OS=Homo sapiens OX=9606 GN=ATP5PB PE=1 SV=2" 8.47 1495.2 - 5.63E+06 - - - -2.4631 - 1.396 0.339 - 254.2 1 2 0 -0.0022 8 0 0 0 4.98E+07 5.92E+07 - - - 2.5503 0.9857 221125_WJC_METTL3_EV_vs_WT_F05.04771.04771.2 0.783 16-Jul K.LTSSNEINK[136.11].E "sp|Q9UPN6|SCAF8_HUMAN,tr|A0A0A0MT33|A0A0A0MT33_HUMAN" 2 1012.528 0.44 58747 4771 2 1012.528933 507.2713 SR-related and CTD-associated factor 8 OS=Homo sapiens OX=9606 GN=SCAF8 PE=1 SV=1 6 1495.4 - 1.61E+06 - - - 0.8829 - 1.251 0.114 - 119.2 1 2 0 0.0009 9 0 0 0 6.52E+06 1.49E+07 - - - 0.5306 0.9507 221125_WJC_METTL3_EV_vs_WT_F05.04773.04773.2 0.0569 16-Jul K.LTSSNEINK.E "sp|Q9UPN6|SCAF8_HUMAN,tr|A0A0A0MT33|A0A0A0MT33_HUMAN" 2 1004.5138 0.45 58749 4773 2 1004.511971 503.2642 SR-related and CTD-associated factor 8 OS=Homo sapiens OX=9606 GN=SCAF8 PE=1 SV=1 6 1495.6 - 1.28E+06 - - - -1.8596 - 1.186 0.091 - 101.9 3 2 0 -0.0019 9 0 0 0 6.52E+06 1.46E+07 - - - -0.0071 0.9988 221125_WJC_METTL3_EV_vs_WT_F05.04777.04777.2 0.0172 14-Sep K.TTQEQLAR[166.11].E "sp|Q9P2E9|RRBP1_HUMAN,tr|A0A087WU26|A0A087WU26_HUMAN,tr|A0A087WVV2|A0A087WVV2_HUMAN,tr|F8W7S5|F8W7S5_HUMAN" 4 955.4962 0.68 58752 4777 2 955.4944 478.7554 Ribosome-binding protein 1 OS=Homo sapiens OX=9606 GN=RRBP1 PE=1 SV=5 5.66 1496.1 - 6.83E+06 - - - -1.9142 - 1.707 0.296 - 502.7 1 2 0 -0.0018 8 0 0 0 6.15E+07 9.08E+07 - - - 2.8394 0.9996 221125_WJC_METTL3_EV_vs_WT_F05.04779.04779.2 0.0202 16-Aug K.AAFGGSGGR.G sp|P35908|K22E_HUMAN 1 778.3722 1.6 58754 4779 2 778.371115 390.1934 "Keratin, type II cytoskeletal 2 epidermal OS=Homo sapiens OX=9606 GN=KRT2 PE=1 SV=2" 9.79 1496.2 - 2.12E+07 - - - -1.3952 - 1.568 0.443 - 166.3 1 2 0 -0.0011 9 0 0 0 2.58E+08 1.62E+08 - - - 3.614 0.9944 221125_WJC_METTL3_EV_vs_WT_F05.04783.04783.2 0.00936 14-Jun K.LSTAC[160.03]PGR.V sp|P55060|XPO2_HUMAN 1 860.4174 0.58 58758 4783 2 860.414662 431.216 Exportin-2 OS=Homo sapiens OX=9606 GN=CSE1L PE=1 SV=3 8.25 1496.5 - 1.96E+06 - - - -3.2252 - 1.616 0.265 - 115.3 2 2 0 -0.0028 8 0 0 0 3.50E+07 6.07E+07 - - - 2.3105 0.9998 221125_WJC_METTL3_EV_vs_WT_F05.04787.04787.2 3.23E-06 18-Nov R.YYGGGSEGGR[166.11].A sp|P14866|HNRPL_HUMAN 1 1011.4285 1.16 58762 4787 2 1011.426885 506.7215 Heterogeneous nuclear ribonucleoprotein L OS=Homo sapiens OX=9606 GN=HNRNPL PE=1 SV=2 6 1496.9 - 1.07E+06 - - - -1.6393 - 1.849 0.569 - 209 1 2 0 -0.0017 10 0 0 0 2.59E+08 2.23E+08 - - - 4.9588 0.9985 221125_WJC_METTL3_EV_vs_WT_F05.04792.04792.2 0.0587 18-Jun R.QGGAPDAGQE.- "sp|P49368|TCPG_HUMAN,tr|B4DUR8|B4DUR8_HUMAN" 2 928.3886 - 58765 4792 2 928.388338 465.2016 T-complex protein 1 subunit gamma OS=Homo sapiens OX=9606 GN=CCT3 PE=1 SV=4 4.09 1497.5 - 9.66E+06 - - - -0.3242 - 1.35 0.292 - 165.1 1 2 0 -0.0003 10 0 0 0 - - - - - 2.0353 0.9998 221125_WJC_METTL3_EV_vs_WT_F05.04793.04793.2 3.03E-05 18-Aug R.YYGGGSEGGR.A sp|P14866|HNRPL_HUMAN 1 1001.4203 1.16 58766 4793 2 1001.419585 501.7174 Heterogeneous nuclear ribonucleoprotein L OS=Homo sapiens OX=9606 GN=HNRNPL PE=1 SV=2 6 1497.5 - 6.81E+06 - - - -0.687 - 1.705 0.541 - 101.8 1 2 0 -0.0007 10 0 0 0 2.59E+08 2.23E+08 - - - 4.526 0.9987 221125_WJC_METTL3_EV_vs_WT_F05.04794.04794.2 0.502 12-Sep R.HVVGEIR.R "sp|P51570|GALK1_HUMAN,tr|K7EII7|K7EII7_HUMAN" 2 808.4555 1.53 58767 4794 2 808.455781 405.235 Galactokinase OS=Homo sapiens OX=9606 GN=GALK1 PE=1 SV=1 6.75 1497.6 - 6.16E+06 - - - 0.303 - 1.744 0.188 - 350.2 1 2 0 0.0002 7 0 0 0 1.76E+08 1.15E+08 - - - 2.1918 0.9958 221125_WJC_METTL3_EV_vs_WT_F05.04795.04795.2 0.365 16-Jul R.EASLGEASK[136.11].L "sp|Q01082|SPTB2_HUMAN,tr|A0A087WUZ3|A0A087WUZ3_HUMAN" 2 898.4487 1.39 58768 4795 2 898.448316 450.2316 "Spectrin beta chain, non-erythrocytic 1 OS=Homo sapiens OX=9606 GN=SPTBN1 PE=1 SV=2" 4.53 1497.6 - 4.80E+06 - - - -0.4563 - 1.505 0.139 - 166 1 2 0 -0.0004 9 0 0 0 4.58E+07 3.31E+07 - - - 1.2502 0.9999 221125_WJC_METTL3_EV_vs_WT_F05.04797.04797.2 6.59E-05 16-Dec K.VVAEPQTQR[166.11].V "sp|Q92615|LAR4B_HUMAN,tr|B5MCU2|B5MCU2_HUMAN,tr|X6RCG6|X6RCG6_HUMAN,tr|V9GYI5|V9GYI5_HUMAN" 4 1036.5541 1.23 58770 4797 2 1036.553672 519.2843 La-related protein 4B OS=Homo sapiens OX=9606 GN=LARP4B PE=1 SV=3 5.97 1497.7 - 2.66E+06 - - - -0.3917 - 1.943 0.491 - 554.6 1 2 0 -0.0004 9 0 0 0 1.15E+09 9.36E+08 - - - 4.5891 0.984 221125_WJC_METTL3_EV_vs_WT_F05.04798.04798.2 0.998 14-Jul K.SQQALVQK[136.11].R "sp|P24539|AT5F1_HUMAN,tr|Q5QNZ2|Q5QNZ2_HUMAN" 2 908.5171 0.83 58771 4798 2 908.51737 455.2658 "ATP synthase F(0) complex subunit B1, mitochondrial OS=Homo sapiens OX=9606 GN=ATP5PB PE=1 SV=2" 8.47 1497.8 - 2.64E+06 - - - 0.3181 - 1.126 0.126 - 137.1 1 2 0 0.0003 8 0 0 0 4.98E+07 6.00E+07 - - - 0.3295 0.9997 221125_WJC_METTL3_EV_vs_WT_F05.04799.04799.2 0.000132 16-Nov K.VVAEPQTQR.V "sp|Q92615|LAR4B_HUMAN,tr|B5MCU2|B5MCU2_HUMAN,tr|X6RCG6|X6RCG6_HUMAN,tr|V9GYI5|V9GYI5_HUMAN" 4 1026.5458 1.23 58772 4799 2 1026.54569 514.2802 La-related protein 4B OS=Homo sapiens OX=9606 GN=LARP4B PE=1 SV=3 5.97 1497.8 - 2.22E+06 - - - -0.1149 - 1.894 0.365 - 484.3 1 2 0 -0.0001 9 0 0 0 1.15E+09 9.36E+08 - - - 3.5846 0.9882 221125_WJC_METTL3_EV_vs_WT_F05.04800.04800.2 0.000263 18-Sep G.EVAGTVTGQK[136.11].R "sp|Q86U44|MTA70_HUMAN,tr|F5H6D8|F5H6D8_HUMAN,tr|H0YFV6|H0YFV6_HUMAN,tr|B4DTN4|B4DTN4_HUMAN" 4 996.5331 0.09 58773 4800 2 996.533171 499.2738 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 6.1 1497.9 - 1.63E+06 - - - 0.0462 - 1.894 0.442 - 301.5 1 1 0 0 10 0 0 0 2.18E+06 2.46E+07 - - - 4.0884 0.9997 221125_WJC_METTL3_EV_vs_WT_F05.04801.04801.2 0.0167 14-Sep R.VDDESMQR[166.11].F sp|Q6P2Q9|PRP8_HUMAN 1 988.4159 1.17 58774 4801 2 988.414943 495.2152 Pre-mRNA-processing-splicing factor 8 OS=Homo sapiens OX=9606 GN=PRPF8 PE=1 SV=2 4.03 1498 - 1.30E+06 - - - -0.9986 - 1.752 0.401 - 293.4 1 2 0 -0.001 8 0 0 0 1.17E+07 9.94E+06 - - - 3.6937 0.9996 221125_WJC_METTL3_EV_vs_WT_F05.04806.04806.2 0.00325 14-Jul K.LSTAC[160.03]PGR[166.11].V sp|P55060|XPO2_HUMAN 1 870.4257 0.55 58777 4806 2 870.424352 436.2201 Exportin-2 OS=Homo sapiens OX=9606 GN=CSE1L PE=1 SV=3 8.25 1498.6 - 4.86E+06 - - - -1.5567 - 1.665 0.419 - 187.5 1 2 0 -0.0014 8 0 0 0 5.19E+07 9.43E+07 - - - 3.6729 0.9816 221125_WJC_METTL3_EV_vs_WT_F05.04809.04809.2 0.48 12-Jun K.ELAPHVK[136.11].K sp|Q8N0X7|SPART_HUMAN 1 800.4636 4.89 58780 4809 2 800.464074 401.2391 Spartin OS=Homo sapiens OX=9606 GN=SPART PE=1 SV=1 6.85 1498.7 - 2.48E+06 - - - 0.6071 - 0.998 0.17 - 159.1 1 2 0 0.0005 7 0 0 0 8.97E+07 1.83E+07 - - - 0.2901 0.9978 221125_WJC_METTL3_EV_vs_WT_F05.04810.04810.2 0.0301 14-Jul K.AVTEMNGR.L "sp|Q13310|PABP4_HUMAN,sp|Q9H361|PABP3_HUMAN,sp|Q4VXU2|PAP1L_HUMAN,sp|P11940|PABP1_HUMAN,tr|A0A7I2V5W9|A0A7I2V5W9_HUMAN,tr|H0YEU6|H0YEU6_HUMAN,tr|A0A7I2YQE4|A0A7I2YQE4_HUMAN,tr|A0A7I2V649|A0A7I2V649_HUMAN,tr|B1ANR0|B1ANR0_HUMAN,tr|A0A6Q8JFT6|A0A6Q8JFT6_HUMAN,tr|A0A7I2V4L7|A0A7I2V4L7_HUMAN,tr|H0YB86|H0YB86_HUMAN,tr|H0YAR2|H0YAR2_HUMAN,tr|E7ERJ7|E7ERJ7_HUMAN,tr|A0A7I2V598|A0A7I2V598_HUMAN,tr|A0A7I2YQ88|A0A7I2YQ88_HUMAN,tr|A0A7I2V4V6|A0A7I2V4V6_HUMAN,tr|H0Y5F5|H0Y5F5_HUMAN,tr|A0A6I8PS38|A0A6I8PS38_HUMAN,tr|A0A6I8PLA1|A0A6I8PLA1_HUMAN,tr|A0A087WTT1|A0A087WTT1_HUMAN,tr|A0A7I2YQ90|A0A7I2YQ90_HUMAN,tr|A0A7I2V4N4|A0A7I2V4N4_HUMAN,tr|E7EQV3|E7EQV3_HUMAN" 24 876.4124 0.31 58781 4810 2 876.410439 439.2135 Polyadenylate-binding protein 4 OS=Homo sapiens OX=9606 GN=PABPC4 PE=1 SV=1 6.05 1498.8 - 1.86E+06 - - - -2.1816 - 1.425 0.318 - 167.5 1 2 0 -0.0019 8 0 0 0 1.02E+08 3.32E+08 - - - 2.4573 0.9811 221125_WJC_METTL3_EV_vs_WT_F05.04812.04812.2 5.88E-07 18-Oct F.MVVNDAGR[166.11]PK[136.11].V "sp|P11142|HSP7C_HUMAN,tr|E9PQQ4|E9PQQ4_HUMAN,tr|E9PNE6|E9PNE6_HUMAN,tr|E9PKE3|E9PKE3_HUMAN,tr|E9PN89|E9PN89_HUMAN,tr|E9PLF4|E9PLF4_HUMAN,tr|E9PK54|E9PK54_HUMAN,tr|E9PN25|E9PN25_HUMAN,tr|E9PPY6|E9PPY6_HUMAN,tr|E9PQK7|E9PQK7_HUMAN" 10 1103.5876 0.12 58783 4812 2 1103.585882 552.8011 Heat shock cognate 71 kDa protein OS=Homo sapiens OX=9606 GN=HSPA8 PE=1 SV=1 8.5 1499 - 991670 - - - -1.5866 - 2.018 0.421 - 316.6 1 1 0 -0.0018 10 0 0 0 1.71E+06 1.47E+07 - - - 4.1098 0.9207 221125_WJC_METTL3_EV_vs_WT_F05.04823.04823.2 0.344 12-Jun K.HTLTQIK[136.11].D sp|P40227|TCPZ_HUMAN 1 847.5007 0.45 58790 4823 2 847.498079 424.7576 T-complex protein 1 subunit zeta OS=Homo sapiens OX=9606 GN=CCT6A PE=1 SV=3 8.76 1500.2 - 7.68E+06 - - - -3.095 - 1.084 0.128 - 115.2 1 2 0 -0.0026 7 0 0 0 6.31E+07 1.42E+08 - - - 0.2412 0.998 221125_WJC_METTL3_EV_vs_WT_F05.04824.04824.2 0.24 12-Aug R.TEEENLR.K "sp|P04637|P53_HUMAN,tr|E7ESS1|E7ESS1_HUMAN,tr|J3KP33|J3KP33_HUMAN,tr|A0A087X1Q1|A0A087X1Q1_HUMAN,tr|A0A0U1RQC9|A0A0U1RQC9_HUMAN,tr|A0A087WT22|A0A087WT22_HUMAN,tr|A0A087WXZ1|A0A087WXZ1_HUMAN" 7 889.4141 1.03 58791 4824 2 889.412713 445.7143 Cellular tumor antigen p53 OS=Homo sapiens OX=9606 GN=TP53 PE=1 SV=4 4.25 1500.2 - 5.40E+06 - - - -1.5876 - 1.65 0.212 - 363.2 1 2 0 -0.0014 7 0 0 0 7.57E+07 7.35E+07 - - - 2.1931 0.9483 221125_WJC_METTL3_EV_vs_WT_F05.04825.04825.2 0.00682 12-Aug Q.NQVLQTK.W "sp|Q7Z794|K2C1B_HUMAN,sp|P04264|K2C1_HUMAN,sp|P35908|K22E_HUMAN" 3 829.4658 1.15 58792 4825 2 829.464763 415.7402 "Keratin, type II cytoskeletal 1b OS=Homo sapiens OX=9606 GN=KRT77 PE=1 SV=3" 8.75 1500.3 - 3.62E+06 - - - -1.2104 - 1.617 0.291 - 476.4 1 1 0 -0.001 7 0 0 0 7.17E+07 6.22E+07 - - - 2.7127 0.9989 221125_WJC_METTL3_EV_vs_WT_F05.04833.04833.2 0.00832 14-Jul K.GNVLGNSK.S sp|Q8NBJ4|GOLM1_HUMAN 1 787.4188 0.94 58798 4833 2 787.417959 394.7167 Golgi membrane protein 1 OS=Homo sapiens OX=9606 GN=GOLM1 PE=1 SV=1 8.75 1501.2 - 3.98E+06 - - - -1.0896 - 1.475 0.302 - 267.1 1 2 0 -0.0009 8 0 0 0 3.69E+07 3.93E+07 - - - 2.4435 0.9992 221125_WJC_METTL3_EV_vs_WT_F05.04834.04834.2 0.00392 14-Jul K.GNVLGNSK[136.11].S sp|Q8NBJ4|GOLM1_HUMAN 1 795.433 1.08 58799 4834 2 795.433295 398.7238 Golgi membrane protein 1 OS=Homo sapiens OX=9606 GN=GOLM1 PE=1 SV=1 8.75 1501.2 - 3.01E+06 - - - 0.3495 - 1.37 0.36 - 253.7 1 2 0 0.0003 8 0 0 0 3.67E+07 3.40E+07 - - - 2.6493 0.9994 221125_WJC_METTL3_EV_vs_WT_F05.04837.04837.2 0.0102 14-Jul K.LEDC[160.03]TPQR.D "sp|O43657|TSN6_HUMAN,tr|A0A087WZU5|A0A087WZU5_HUMAN,tr|A0A087WYV6|A0A087WYV6_HUMAN" 3 1017.4549 1.59 58802 4837 2 1017.45363 509.7347 Tetraspanin-6 OS=Homo sapiens OX=9606 GN=TSPAN6 PE=1 SV=1 4.37 1501.4 - 802904 - - - -1.2915 - 1.655 0.343 - 191.8 1 2 0 -0.0013 8 0 0 0 3.52E+07 2.21E+07 - - - 3.0934 0.9939 221125_WJC_METTL3_EV_vs_WT_F05.04841.04841.2 0.073 14-Aug R.DSTLGAGR[166.11].R sp|Q9ULX3|NOB1_HUMAN 1 785.3907 0.63 58804 4841 2 785.390184 393.7026 RNA-binding protein NOB1 OS=Homo sapiens OX=9606 GN=NOB1 PE=1 SV=1 5.84 1501.9 - 4.84E+06 - - - -0.6583 - 1.638 0.083 - 284.1 2 2 0 -0.0005 8 0 0 0 3.07E+07 4.87E+07 - - - 1.0077 0.9989 221125_WJC_METTL3_EV_vs_WT_F05.04843.04843.2 0.0427 14-Jul R.ELANQVSK[136.11].D sp|Q9NR30|DDX21_HUMAN 1 895.4854 0.89 58806 4843 2 895.484631 448.75 Nucleolar RNA helicase 2 OS=Homo sapiens OX=9606 GN=DDX21 PE=1 SV=5 6.1 1502.1 - 3.94E+06 - - - -0.9101 - 1.711 0.236 - 250.2 1 2 0 -0.0008 8 0 0 0 9.60E+07 1.08E+08 - - - 2.4036 0.9995 221125_WJC_METTL3_EV_vs_WT_F05.04844.04844.2 0.0489 16-Sep K.TSATALGDK.G "sp|Q14241|ELOA1_HUMAN,tr|A0A024RAC6|A0A024RAC6_HUMAN" 2 862.4396 0.56 58807 4844 2 862.439923 432.2271 Elongin-A OS=Homo sapiens OX=9606 GN=ELOA PE=1 SV=2 5.5 1502.1 - 2.16E+06 - - - 0.3606 - 1.992 0.283 - 391.5 1 2 0 0.0003 9 0 0 0 4.92E+07 8.71E+07 - - - 3.1249 0.9974 221125_WJC_METTL3_EV_vs_WT_F05.04845.04845.2 0.191 14-Jul K.C[160.03]GGTLEER.A sp|Q12874|SF3A3_HUMAN 1 920.4022 22.01 58808 4845 2 920.401145 461.2084 Splicing factor 3A subunit 3 OS=Homo sapiens OX=9606 GN=SF3A3 PE=1 SV=1 4.53 1502.2 - 1.10E+06 - - - -1.1256 - 1.395 0.234 - 171.7 1 2 0 -0.001 8 0 0 0 2.77E+07 1.26E+06 - - - 1.773 0.9901 221125_WJC_METTL3_EV_vs_WT_F05.04853.04853.2 0.263 14-Jul R.VELSNGEK[136.11].R sp|P84103|SRSF3_HUMAN 1 882.4538 1.69 58814 4853 2 882.452007 442.2342 Serine\arginine-rich splicing factor 3 OS=Homo sapiens OX=9606 GN=SRSF3 PE=1 SV=1 4.53 1503.1 - 3.93E+06 - - - -2.0454 - 1.301 0.183 - 116.6 1 2 0 -0.0018 8 0 0 0 1.41E+08 8.35E+07 - - - 1.1857 0.999 221125_WJC_METTL3_EV_vs_WT_F05.04855.04855.2 0.0688 12-Aug K.SDEMNVK.V "sp|P60660|MYL6_HUMAN,tr|F8W1R7|F8W1R7_HUMAN,tr|G3V1V0|G3V1V0_HUMAN,tr|B7Z6Z4|B7Z6Z4_HUMAN,tr|G8JLA2|G8JLA2_HUMAN,tr|J3KND3|J3KND3_HUMAN,tr|F8VPF3|F8VPF3_HUMAN" 7 821.3589 0.99 58816 4855 2 821.359623 411.6867 Myosin light polypeptide 6 OS=Homo sapiens OX=9606 GN=MYL6 PE=1 SV=2 4.37 1503.2 - 6.31E+06 - - - 0.8583 - 1.24 0.381 - 328.3 1 2 0 0.0007 7 0 0 0 1.27E+08 1.28E+08 - - - 2.5364 0.9988 221125_WJC_METTL3_EV_vs_WT_F05.04859.04859.2 0.0189 16-Jul R.IVSQPQPAR.R "sp|Q8IX12|CCAR1_HUMAN,tr|F5H2E6|F5H2E6_HUMAN,tr|F5H1H2|F5H1H2_HUMAN,tr|A0A0C4DGG8|A0A0C4DGG8_HUMAN,tr|F5H3E1|F5H3E1_HUMAN" 5 994.556 4.74 58820 4859 2 994.555439 498.2853 Cell division cycle and apoptosis regulator protein 1 OS=Homo sapiens OX=9606 GN=CCAR1 PE=1 SV=2 9.75 1503.6 - 514355 - - - -0.543 - 1.524 0.264 - 149 1 2 0 -0.0005 9 0 0 0 6.37E+08 1.34E+08 - - - 2.2097 0.9998 221125_WJC_METTL3_EV_vs_WT_F05.04866.04866.2 0.0111 12-Aug K.SDEMNVK[136.11].V "sp|P60660|MYL6_HUMAN,tr|F8W1R7|F8W1R7_HUMAN,tr|G3V1V0|G3V1V0_HUMAN,tr|B7Z6Z4|B7Z6Z4_HUMAN,tr|G8JLA2|G8JLA2_HUMAN,tr|J3KND3|J3KND3_HUMAN,tr|F8VPF3|F8VPF3_HUMAN" 7 829.3731 1.05 58825 4866 2 829.372549 415.6938 Myosin light polypeptide 6 OS=Homo sapiens OX=9606 GN=MYL6 PE=1 SV=2 4.37 1504.6 - 9.76E+06 - - - -0.6861 - 1.626 0.457 - 356.8 1 2 0 -0.0006 7 0 0 0 1.27E+08 1.22E+08 - - - 3.9565 0.9974 221125_WJC_METTL3_EV_vs_WT_F05.04868.04868.2 2.27 12-Aug R.RLAALQK.R sp|Q99459|CDC5L_HUMAN 1 798.5076 1.25 58827 4868 2 798.507782 400.2611 Cell division cycle 5-like protein OS=Homo sapiens OX=9606 GN=CDC5L PE=1 SV=2 11 1504.7 - 2.67E+06 - - - 0.263 - 1.662 0.128 - 313.2 1 2 0 0.0002 7 0 0 0 3.00E+07 2.40E+07 - - - 1.596 0.9571 221125_WJC_METTL3_EV_vs_WT_F05.04869.04869.2 0.0396 14-Jul R.DSTLGAGR.R sp|Q9ULX3|NOB1_HUMAN 1 775.3824 0.65 58828 4869 2 775.383202 388.6985 RNA-binding protein NOB1 OS=Homo sapiens OX=9606 GN=NOB1 PE=1 SV=1 5.84 1504.7 - 2.13E+06 - - - 0.9943 - 1.246 0.036 - 176.9 2 2 0 0.0008 8 0 0 0 3.21E+07 4.92E+07 - - - -0.1645 0.9948 221125_WJC_METTL3_EV_vs_WT_F05.04870.04870.2 0.138 13/18 K.ALQSGPPQSR[166.11].R sp|O00425|IF2B3_HUMAN 1 1049.5493 13.96 58829 4870 2 1049.551677 525.7819 Insulin-like growth factor 2 mRNA-binding protein 3 OS=Homo sapiens OX=9606 GN=IGF2BP3 PE=1 SV=2 9.79 1504.8 - 851881 - - - 2.2391 - 1.837 0.146 - 771.7 1 2 0 0.0024 10 0 0 0 2.81E+08 2.01E+07 - - - 1.8161 0.9364 221125_WJC_METTL3_EV_vs_WT_F05.04874.04874.2 9.1 12-Aug K.YLR[166.11]EEVK[136.11].T "sp|Q92615|LAR4B_HUMAN,sp|Q71RC2|LARP4_HUMAN,tr|Q96J85|Q96J85_HUMAN,tr|X6RLN4|X6RLN4_HUMAN" 4 953.5301 1.98 58831 4874 2 953.530051 477.7723 La-related protein 4B OS=Homo sapiens OX=9606 GN=LARP4B PE=1 SV=3 6.14 1505.4 - 5.63E+06 - - - -0.0535 - 1.461 0.098 - 374 1 2 1 -0.0001 7 0 0 0 1.22E+08 6.15E+07 - - - 0.9661 0.9996 221125_WJC_METTL3_EV_vs_WT_F05.04876.04876.2 0.00137 14-Jul R.SGQDPYAR[166.11].N sp|Q10471|GALT2_HUMAN 1 902.4122 1.7 58833 4876 2 902.411546 452.2134 Polypeptide N-acetylgalactosaminyltransferase 2 OS=Homo sapiens OX=9606 GN=GALNT2 PE=1 SV=1 5.55 1505.5 - 1.17E+07 - - - -0.6859 - 1.46 0.415 - 149.3 1 2 0 -0.0006 8 0 0 0 1.99E+08 1.17E+08 - - - 3.2473 0.8808 221125_WJC_METTL3_EV_vs_WT_F05.04877.04877.2 2.32 12-Aug K.YLREEVK.T "sp|Q92615|LAR4B_HUMAN,sp|Q71RC2|LARP4_HUMAN,tr|Q96J85|Q96J85_HUMAN,tr|X6RLN4|X6RLN4_HUMAN" 4 935.5076 1.98 58834 4877 2 935.507626 468.7611 La-related protein 4B OS=Homo sapiens OX=9606 GN=LARP4B PE=1 SV=3 6.14 1505.5 - 6.22E+06 - - - -0.0064 - 1.46 0.035 - 330.6 1 2 1 0 7 0 0 0 1.22E+08 6.15E+07 - - - 0.4986 0.9997 221125_WJC_METTL3_EV_vs_WT_F05.04878.04878.2 0.0074 18-Oct K.ALQSGPPQSR.R sp|O00425|IF2B3_HUMAN 1 1039.5411 1.39 58835 4878 2 1039.540594 520.7778 Insulin-like growth factor 2 mRNA-binding protein 3 OS=Homo sapiens OX=9606 GN=IGF2BP3 PE=1 SV=2 9.79 1505.6 - 1.70E+06 - - - -0.4454 - 2.079 0.325 - 496.4 1 2 0 -0.0005 10 0 0 0 2.15E+07 1.54E+07 - - - 3.4842 0.9342 221125_WJC_METTL3_EV_vs_WT_F05.04879.04879.2 0.0459 16-Jul Y.NTTSAVTVK[136.11].S "sp|P61513|RL37A_HUMAN,tr|C9J4Z3|C9J4Z3_HUMAN" 2 927.5117 1.02 58836 4879 2 927.511321 464.7631 60S ribosomal protein L37a OS=Homo sapiens OX=9606 GN=RPL37A PE=1 SV=2 8.75 1505.7 - 1.48E+06 - - - -0.3666 - 1.709 0.223 - 232.5 1 1 0 -0.0003 9 0 0 0 4.87E+07 4.75E+07 - - - 2.2384 0.9984 221125_WJC_METTL3_EV_vs_WT_F05.04885.04885.2 0.906 16-Aug K.AMQDAEVSK[136.11].S "sp|P38646|GRP75_HUMAN,tr|H0Y8K0|H0Y8K0_HUMAN,tr|A0A7I2V2S7|A0A7I2V2S7_HUMAN,tr|A0A7I2V2G2|A0A7I2V2G2_HUMAN,tr|A0A7I2V3F7|A0A7I2V3F7_HUMAN,tr|A0A7I2YQB2|A0A7I2YQB2_HUMAN,tr|D6RCD7|D6RCD7_HUMAN" 7 985.463 0.32 58840 4885 2 985.463006 493.7388 "Stress-70 protein, mitochondrial OS=Homo sapiens OX=9606 GN=HSPA9 PE=1 SV=2" 4.37 1506.4 - 6.47E+06 - - - 0.0101 - 1.624 0.209 - 205.9 1 2 0 0 9 0 0 0 1.78E+08 5.49E+08 - - - 1.9875 0.9901 221125_WJC_METTL3_EV_vs_WT_F05.04886.04886.2 0.77 14-Jun R.SVGQYDNR[166.11].G "sp|P13861|KAP2_HUMAN,tr|H7C1L0|H7C1L0_HUMAN" 2 947.4336 1.57 58841 4886 2 947.434164 474.7241 cAMP-dependent protein kinase type II-alpha regulatory subunit OS=Homo sapiens OX=9606 GN=PRKAR2A PE=1 SV=2 5.55 1506.4 - 4.51E+06 - - - 0.5647 - 1.09 0.189 - 104.4 1 2 0 0.0005 8 0 0 0 8.62E+07 5.50E+07 - - - 0.6967 0.9343 221125_WJC_METTL3_EV_vs_WT_F05.04888.04888.2 0.153 16-Aug Y.NTTSAVTVK.S "sp|P61513|RL37A_HUMAN,tr|C9J4Z3|C9J4Z3_HUMAN" 2 919.4975 1.02 58843 4888 2 919.497243 460.756 60S ribosomal protein L37a OS=Homo sapiens OX=9606 GN=RPL37A PE=1 SV=2 8.75 1506.5 - 2.91E+06 - - - -0.2371 - 1.709 0.222 - 379.5 1 1 0 -0.0002 9 0 0 0 4.87E+07 4.75E+07 - - - 2.231 0.9995 221125_WJC_METTL3_EV_vs_WT_F05.04890.04890.2 0.101 14-Jul K.LEDC[160.03]TPQR[166.11].D "sp|O43657|TSN6_HUMAN,tr|A0A087WZU5|A0A087WZU5_HUMAN,tr|A0A087WYV6|A0A087WYV6_HUMAN" 3 1027.4632 1.68 58845 4890 2 1027.463447 514.7389 Tetraspanin-6 OS=Homo sapiens OX=9606 GN=TSPAN6 PE=1 SV=1 4.37 1506.7 - 967667 - - - 0.2268 - 1.476 0.379 - 190.5 1 2 0 0.0002 8 0 0 0 4.08E+07 2.43E+07 - - - 3.0144 0.9983 221125_WJC_METTL3_EV_vs_WT_F05.04896.04896.2 0.0259 14-Jul R.SVGQYDNR.G "sp|P13861|KAP2_HUMAN,tr|H7C1L0|H7C1L0_HUMAN" 2 937.4254 1.57 58849 4896 2 937.425754 469.72 cAMP-dependent protein kinase type II-alpha regulatory subunit OS=Homo sapiens OX=9606 GN=PRKAR2A PE=1 SV=2 5.55 1507.4 - 9.74E+06 - - - 0.4214 - 1.185 0.329 - 159.3 1 2 0 0.0004 8 0 0 0 8.62E+07 5.50E+07 - - - 1.9828 0.9998 221125_WJC_METTL3_EV_vs_WT_F05.04897.04897.2 0.00692 16-Nov K.QLEAETGC[160.03]K.L "sp|Q96PU8|QKI_HUMAN,tr|F5GYM3|F5GYM3_HUMAN,tr|F5GXS8|F5GXS8_HUMAN,tr|F5H8C8|F5H8C8_HUMAN" 4 1034.4703 1.25 58850 4897 2 1034.471333 518.2424 Protein quaking OS=Homo sapiens OX=9606 GN=QKI PE=1 SV=1 4.53 1507.5 - 3.57E+06 - - - 1.0372 - 2.172 0.477 - 644.6 1 2 0 0.0011 9 0 0 0 5.76E+08 4.60E+08 - - - 4.8078 0.9997 221125_WJC_METTL3_EV_vs_WT_F05.04899.04899.2 0.00131 16-Aug K.AMQDAEVSK.S "sp|P38646|GRP75_HUMAN,tr|H0Y8K0|H0Y8K0_HUMAN,tr|A0A7I2V2S7|A0A7I2V2S7_HUMAN,tr|A0A7I2V2G2|A0A7I2V2G2_HUMAN,tr|A0A7I2V3F7|A0A7I2V3F7_HUMAN,tr|A0A7I2YQB2|A0A7I2YQB2_HUMAN,tr|D6RCD7|D6RCD7_HUMAN" 7 977.4488 0.32 58852 4899 2 977.448866 489.7317 "Stress-70 protein, mitochondrial OS=Homo sapiens OX=9606 GN=HSPA9 PE=1 SV=2" 4.37 1507.5 - 5.47E+06 - - - 0.0716 - 1.714 0.399 - 200.2 1 2 0 0.0001 9 0 0 0 1.78E+08 5.49E+08 - - - 3.5469 0.9984 221125_WJC_METTL3_EV_vs_WT_F05.04900.04900.2 0.0879 12-Jul R.GPLPVKR.G "sp|Q96E39|RMXL1_HUMAN,sp|P38159|RBMX_HUMAN,tr|H3BUY5|H3BUY5_HUMAN,tr|A0A1B0GUK8|A0A1B0GUK8_HUMAN,tr|H3BT71|H3BT71_HUMAN,tr|H0Y6E7|H0Y6E7_HUMAN" 6 765.4861 1.84 58853 4900 2 765.486107 383.7503 "RNA binding motif protein, X-linked-like-1 OS=Homo sapiens OX=9606 GN=RBMXL1 PE=1 SV=1" 11 1507.6 - 2.11E+06 - - - -0.0013 - 1.168 0.33 - 250.1 1 2 0 0 7 0 0 0 1.58E+08 8.60E+07 - - - 1.9704 0.9999 221125_WJC_METTL3_EV_vs_WT_F05.04901.04901.2 0.000271 16-Oct K.QLEAETGC[160.03]K[136.11].L "sp|Q96PU8|QKI_HUMAN,tr|F5GYM3|F5GYM3_HUMAN,tr|F5GXS8|F5GXS8_HUMAN,tr|F5H8C8|F5H8C8_HUMAN" 4 1042.4845 1.13 58854 4901 2 1042.485049 522.2495 Protein quaking OS=Homo sapiens OX=9606 GN=QKI PE=1 SV=1 4.53 1507.7 - 2.09E+06 - - - 0.565 - 2.114 0.479 - 522.3 1 2 0 0.0006 9 0 0 0 5.76E+08 5.10E+08 - - - 4.7444 0.9939 221125_WJC_METTL3_EV_vs_WT_F05.04903.04903.2 0.0314 16-Jun R.SAVPPGADK[136.11].K "sp|P46783|RS10_HUMAN,tr|F6U211|F6U211_HUMAN,tr|A0A1W2PQS6|A0A1W2PQS6_HUMAN,tr|A0A2R8YFH6|A0A2R8YFH6_HUMAN,tr|A0A2R8Y7H1|A0A2R8Y7H1_HUMAN,tr|S4R435|S4R435_HUMAN" 6 848.4483 605.24 58855 4903 2 848.44826 425.2314 40S ribosomal protein S10 OS=Homo sapiens OX=9606 GN=RPS10 PE=1 SV=1 5.55 1507.9 - 6.41E+06 - - - -0.0849 - 1.082 0.229 - 122 1 2 0 -0.0001 9 0 0 0 1.12E+11 1.86E+08 - - - 0.9604 0.9997 221125_WJC_METTL3_EV_vs_WT_F05.04905.04905.2 0.00177 16-Oct R.IVSQPQPAR[166.11].R "sp|Q8IX12|CCAR1_HUMAN,tr|F5H2E6|F5H2E6_HUMAN,tr|F5H1H2|F5H1H2_HUMAN,tr|A0A0C4DGG8|A0A0C4DGG8_HUMAN,tr|F5H3E1|F5H3E1_HUMAN" 5 1004.5642 4.74 58856 4905 2 1004.563828 503.2894 Cell division cycle and apoptosis regulator protein 1 OS=Homo sapiens OX=9606 GN=CCAR1 PE=1 SV=2 9.75 1508.1 - 4.62E+06 - - - -0.4191 - 1.585 0.428 - 366.3 1 2 0 -0.0004 9 0 0 0 6.37E+08 1.34E+08 - - - 3.5346 0.9977 221125_WJC_METTL3_EV_vs_WT_F05.04914.04914.2 0.0251 16-Jul R.SSPATADKR.Q "sp|Q8TF72|SHRM3_HUMAN,tr|A0A2R8Y5P9|A0A2R8Y5P9_HUMAN" 2 931.4723 611.53 58863 4914 2 931.472965 466.7434 Protein Shroom3 OS=Homo sapiens OX=9606 GN=SHROOM3 PE=1 SV=2 8.46 1509.1 - 2.17E+07 - - - 0.7043 - 1.247 0.286 - 167.8 1 2 0 0.0007 9 0 0 0 6.28E+09 1.03E+07 - - - 1.7918 0.9918 221125_WJC_METTL3_EV_vs_WT_F05.04915.04915.2 0.137 16-Nov K.IQNGTSGIR[166.11].F sp|P55795|HNRH2_HUMAN 1 954.5122 0.49 58864 4915 2 954.508449 478.2634 Heterogeneous nuclear ribonucleoprotein H2 OS=Homo sapiens OX=9606 GN=HNRNPH2 PE=1 SV=1 9.75 1509.2 - 7.88E+06 - - - -3.9434 - 2.05 0.179 - 313.1 1 2 0 -0.0038 9 0 0 0 2.93E+08 5.96E+08 - - - 2.4387 1 221125_WJC_METTL3_EV_vs_WT_F05.04917.04917.3 8.01E-06 Dec-36 R.K[136.11]QDSGHLDLR[166.11].N "sp|Q86U44|MTA70_HUMAN,tr|B4E349|B4E349_HUMAN,tr|F5H6D8|F5H6D8_HUMAN,tr|B4DTN4|B4DTN4_HUMAN" 4 1185.6221 0.05 58866 4917 3 1185.622042 396.2146 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 6.75 1509.2 - 5.25E+06 - - - -0.0531 - 2.542 0.543 - 176.3 1 2 0 -0.0001 10 0 0 0 3.72E+06 8.15E+07 - - - 7.3185 0.993 221125_WJC_METTL3_EV_vs_WT_F05.04925.04925.2 0.249 14-Jun K.SVSDYDGK[136.11].L "sp|P07237|PDIA1_HUMAN,tr|A0A7P0TA97|A0A7P0TA97_HUMAN,tr|A0A7P0T8C0|A0A7P0T8C0_HUMAN,tr|H7BZ94|H7BZ94_HUMAN,tr|A0A7P0TA71|A0A7P0TA71_HUMAN,tr|I3L4M2|I3L4M2_HUMAN,tr|A0A7P0T9D6|A0A7P0T9D6_HUMAN,tr|A0A7P0T9K9|A0A7P0T9K9_HUMAN,tr|H0Y3Z3|H0Y3Z3_HUMAN,tr|A0A7P0TA35|A0A7P0TA35_HUMAN,tr|I3L514|I3L514_HUMAN,tr|A0A7P0TB26|A0A7P0TB26_HUMAN,tr|A0A7P0T9U6|A0A7P0T9U6_HUMAN,tr|I3L3P5|I3L3P5_HUMAN,tr|A0A7P0T8J3|A0A7P0T8J3_HUMAN,tr|A0A7P0T8X1|A0A7P0T8X1_HUMAN" 16 877.3909 0.9 58872 4925 2 877.39147 439.7027 Protein disulfide-isomerase OS=Homo sapiens OX=9606 GN=P4HB PE=1 SV=3 4.21 1510 - 3.96E+06 - - - 0.6759 - 1.11 0.218 - 103.5 1 2 0 0.0006 8 0 0 0 1.83E+08 2.03E+08 - - - 0.9657 0.996 221125_WJC_METTL3_EV_vs_WT_F05.04926.04926.2 0.101 14-Jun K.SVSDYDGK.L "sp|P07237|PDIA1_HUMAN,tr|A0A7P0TA97|A0A7P0TA97_HUMAN,tr|A0A7P0T8C0|A0A7P0T8C0_HUMAN,tr|H7BZ94|H7BZ94_HUMAN,tr|A0A7P0TA71|A0A7P0TA71_HUMAN,tr|I3L4M2|I3L4M2_HUMAN,tr|A0A7P0T9D6|A0A7P0T9D6_HUMAN,tr|A0A7P0T9K9|A0A7P0T9K9_HUMAN,tr|H0Y3Z3|H0Y3Z3_HUMAN,tr|A0A7P0TA35|A0A7P0TA35_HUMAN,tr|I3L514|I3L514_HUMAN,tr|A0A7P0TB26|A0A7P0TB26_HUMAN,tr|A0A7P0T9U6|A0A7P0T9U6_HUMAN,tr|I3L3P5|I3L3P5_HUMAN,tr|A0A7P0T8J3|A0A7P0T8J3_HUMAN,tr|A0A7P0T8X1|A0A7P0T8X1_HUMAN" 16 869.3767 0.97 58873 4926 2 869.376299 435.6956 Protein disulfide-isomerase OS=Homo sapiens OX=9606 GN=P4HB PE=1 SV=3 4.21 1510 - 3.77E+06 - - - -0.4348 - 1.075 0.274 - 93.5 1 2 0 -0.0004 8 0 0 0 1.70E+08 1.75E+08 - - - 1.2828 0.9947 221125_WJC_METTL3_EV_vs_WT_F05.04928.04928.2 0.342 14-Aug K.QASEGPLK.G "sp|P04406|G3P_HUMAN,tr|E7EUT5|E7EUT5_HUMAN" 2 828.4341 0.34 58875 4928 2 828.435099 415.2243 Glyceraldehyde-3-phosphate dehydrogenase OS=Homo sapiens OX=9606 GN=GAPDH PE=1 SV=3 6 1510.1 - 2.14E+06 - - - 1.1673 - 1.334 0.192 - 288.9 1 2 0 0.001 8 0 0 0 1.05E+10 3.06E+10 - - - 1.328 0.9983 221125_WJC_METTL3_EV_vs_WT_F05.04933.04933.2 0.688 14-Aug R.TTQEEQLR[166.11].Q sp|P12270|TPR_HUMAN 1 1013.5017 2.24 58878 4933 2 1013.500283 507.7581 Nucleoprotein TPR OS=Homo sapiens OX=9606 GN=TPR PE=1 SV=3 4.53 1510.6 - 1.02E+06 - - - -1.406 - 1.673 0.226 - 366.5 1 2 0 -0.0014 8 0 0 0 8.80E+07 3.94E+07 - - - 2.2619 0.9991 221125_WJC_METTL3_EV_vs_WT_F05.04937.04937.2 0.0989 18-Aug K.VLSGQDTEDR[166.11].S "sp|O95562|SFT2B_HUMAN,tr|Q5TIH2|Q5TIH2_HUMAN" 2 1128.5287 1.19 58880 4937 2 1128.52871 565.2716 Vesicle transport protein SFT2B OS=Homo sapiens OX=9606 GN=SFT2D2 PE=1 SV=1 4.03 1511.1 - 457874 - - - 0.0523 - 1.201 0.388 - 128.7 1 2 0 0.0001 10 0 0 0 6.67E+06 5.61E+06 - - - 2.418 0.9996 221125_WJC_METTL3_EV_vs_WT_F05.04938.04938.2 0.000137 20-Sep R.AGVVANDAGDR[166.11].V "sp|Q0VDF9|HSP7E_HUMAN,tr|H7C2A1|H7C2A1_HUMAN" 2 1053.5079 0.08 58881 4938 2 1053.50587 527.7612 Heat shock 70 kDa protein 14 OS=Homo sapiens OX=9606 GN=HSPA14 PE=1 SV=1 4.21 1511.3 - 554148 - - - -1.8851 - 1.856 0.48 - 368.7 1 2 0 -0.002 11 0 0 0 1.80E+06 2.37E+07 - - - 4.2586 0.9776 221125_WJC_METTL3_EV_vs_WT_F05.04943.04943.2 1.65 14-Oct K.IAVHC[160.03]TVR[166.11].G "sp|P62913|RL11_HUMAN,tr|Q5VVC8|Q5VVC8_HUMAN" 2 964.5152 1.73 58884 4943 2 964.513459 483.2649 60S ribosomal protein L11 OS=Homo sapiens OX=9606 GN=RPL11 PE=1 SV=2 8.26 1511.8 - 2.40E+07 - - - -1.7947 - 1.337 0.078 - 477.3 1 2 0 -0.0017 8 0 0 0 6.17E+08 3.58E+08 - - - 0.4925 0.9993 221125_WJC_METTL3_EV_vs_WT_F05.04947.04947.2 0.0156 14-Aug R.QQQEEALR.R "sp|Q6Y7W6|GGYF2_HUMAN,tr|A0A7I2V3H7|A0A7I2V3H7_HUMAN,tr|I1E4Y6|I1E4Y6_HUMAN,tr|A0A7I2V516|A0A7I2V516_HUMAN,tr|A0A7I2V3H0|A0A7I2V3H0_HUMAN,tr|A0A7I2V361|A0A7I2V361_HUMAN,tr|E7ESB6|E7ESB6_HUMAN" 7 1000.4938 3.57 58886 4947 2 1000.491516 501.2542 GRB10-interacting GYF protein 2 OS=Homo sapiens OX=9606 GN=GIGYF2 PE=1 SV=1 4.53 1512.3 - 8.27E+06 - - - -2.2549 - 1.737 0.395 - 369.3 1 2 0 -0.0023 8 0 0 0 2.62E+08 7.34E+07 - - - 3.623 0.9997 221125_WJC_METTL3_EV_vs_WT_F05.04950.04950.2 0.000265 14-Aug R.QQQEEALR[166.11].R "sp|Q6Y7W6|GGYF2_HUMAN,tr|A0A7I2V3H7|A0A7I2V3H7_HUMAN,tr|I1E4Y6|I1E4Y6_HUMAN,tr|A0A7I2V516|A0A7I2V516_HUMAN,tr|A0A7I2V3H0|A0A7I2V3H0_HUMAN,tr|A0A7I2V361|A0A7I2V361_HUMAN,tr|E7ESB6|E7ESB6_HUMAN" 7 1010.502 3.57 58889 4950 2 1010.501204 506.2583 GRB10-interacting GYF protein 2 OS=Homo sapiens OX=9606 GN=GIGYF2 PE=1 SV=1 4.53 1512.5 - 3.36E+06 - - - -0.8293 - 1.59 0.454 - 438.6 1 2 0 -0.0008 8 0 0 0 2.62E+08 7.34E+07 - - - 3.7926 0.9995 221125_WJC_METTL3_EV_vs_WT_F05.04954.04954.2 0.0784 20-Nov R.VGQAMASTEEK.A sp|P46977|STT3A_HUMAN 1 1149.5336 1.71 58891 4954 2 1149.531126 575.7741 Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit STT3A OS=Homo sapiens OX=9606 GN=STT3A PE=1 SV=2 4.53 1513 - 641668 - - - -2.1417 - 2.056 0.416 - 360.8 1 2 0 -0.0025 11 0 0 0 1.84E+07 1.08E+07 - - - 4.0626 0.9997 221125_WJC_METTL3_EV_vs_WT_F05.04960.04960.2 6.69E-06 22-Dec R.GPAGDATVASEK.E "sp|Q15758|AAAT_HUMAN,tr|M0QXM4|M0QXM4_HUMAN" 2 1101.5302 3.07 58895 4960 2 1101.528623 551.7724 Neutral amino acid transporter B(0) OS=Homo sapiens OX=9606 GN=SLC1A5 PE=1 SV=2 4.37 1513.7 - 1.70E+06 - - - -1.448 - 2.363 0.381 - 243.7 1 2 0 -0.0016 12 0 0 0 3.52E+07 1.15E+07 - - - 4.1172 0.9429 221125_WJC_METTL3_EV_vs_WT_F05.04963.04963.2 0.213 12-Jun R.NTTIPTK[136.11].K "sp|P38646|GRP75_HUMAN,sp|P54652|HSP72_HUMAN,sp|P11142|HSP7C_HUMAN,tr|E9PNE6|E9PNE6_HUMAN,tr|A8K7Q2|A8K7Q2_HUMAN,tr|E9PKE3|E9PKE3_HUMAN,tr|A0A7I2V2S7|A0A7I2V2S7_HUMAN,tr|A0A7I2V2G2|A0A7I2V2G2_HUMAN,tr|E9PS65|E9PS65_HUMAN,tr|A0A7I2YQB2|A0A7I2YQB2_HUMAN,tr|D6RCD7|D6RCD7_HUMAN" 11 781.4425 0.18 58896 4963 2 781.440014 391.7285 "Stress-70 protein, mitochondrial OS=Homo sapiens OX=9606 GN=HSPA9 PE=1 SV=2" 8.75 1514.1 - 3.41E+08 - - - -3.2056 - 1.386 0.061 - 182.4 1 2 0 -0.0025 7 0 0 0 3.84E+09 2.12E+10 - - - 0.525 0.9996 221125_WJC_METTL3_EV_vs_WT_F05.04997.04997.2 1.29E-05 16-Jul R.AAANEQLTR[166.11].A "sp|Q9NX63|MIC19_HUMAN,tr|A0A286YEX5|A0A286YEX5_HUMAN,tr|F8WAR4|F8WAR4_HUMAN,tr|C9JRZ6|C9JRZ6_HUMAN" 4 982.5071 2 58907 4997 2 982.504642 492.2608 MICOS complex subunit MIC19 OS=Homo sapiens OX=9606 GN=CHCHD3 PE=1 SV=1 6.05 1518.5 - 1.07E+07 - - - -2.5303 - 2.008 0.516 - 203.7 1 2 0 -0.0025 9 0 0 0 1.07E+09 5.34E+08 - - - 4.8683 0.9986 221125_WJC_METTL3_EV_vs_WT_F05.05014.05014.2 0.383 16-Oct R.TVDPETQAR[166.11].L "sp|O75179|ANR17_HUMAN,sp|Q8IWZ3|ANKH1_HUMAN,tr|E9PDP5|E9PDP5_HUMAN,tr|H0YM23|H0YM23_HUMAN,tr|A0A1W2PQ15|A0A1W2PQ15_HUMAN,tr|D6RHC4|D6RHC4_HUMAN" 6 1025.5017 1.66 58911 5014 2 1025.49912 513.7581 Ankyrin repeat domain-containing protein 17 OS=Homo sapiens OX=9606 GN=ANKRD17 PE=1 SV=3 4.37 1520.9 - 4.99E+06 - - - -2.5236 - 1.778 0.332 - 299.4 1 2 0 -0.0026 9 0 0 0 4.52E+08 2.73E+08 - - - 3.1573 0.9839 221125_WJC_METTL3_EV_vs_WT_F05.05019.05019.2 0.0503 14-Aug K.QLSESQVK[136.11].S "sp|P67775|PP2AA_HUMAN,tr|E5RI56|E5RI56_HUMAN" 2 925.496 0.68 58913 5019 2 925.491885 463.7553 Serine\threonine-protein phosphatase 2A catalytic subunit alpha isoform OS=Homo sapiens OX=9606 GN=PPP2CA PE=1 SV=1 6 1521.5 - 6.12E+06 - - - -4.4581 - 1.602 0.232 - 338.9 1 2 0 -0.0041 8 0 0 0 7.59E+07 1.12E+08 - - - 2.1745 0.9995 221125_WJC_METTL3_EV_vs_WT_F05.05021.05021.2 0.113 18-Oct R.LAAEDATNEK[136.11].Q sp|P07196|NFL_HUMAN 1 1068.5179 2.57 58914 5021 2 1068.516506 535.2662 Neurofilament light polypeptide OS=Homo sapiens OX=9606 GN=NEFL PE=1 SV=3 4.14 1521.7 - 1.18E+07 - - - -1.2747 - 2.064 0.313 - 304.9 1 2 0 -0.0014 10 0 0 0 4.19E+08 1.63E+08 - - - 3.3751 0.9999 221125_WJC_METTL3_EV_vs_WT_F05.05036.05036.2 0.00146 16-Nov R.TDTGEPMGR.G sp|P07900|HS90A_HUMAN 1 962.4127 0.57 58923 5036 2 962.413198 482.2136 Heat shock protein HSP 90-alpha OS=Homo sapiens OX=9606 GN=HSP90AA1 PE=1 SV=5 4.37 1523.4 - 1.68E+06 - - - 0.4707 - 2.219 0.476 - 519.4 1 2 0 0.0005 9 0 0 0 4.33E+07 7.62E+07 - - - 4.8625 0.998 221125_WJC_METTL3_EV_vs_WT_F05.05037.05037.2 0.0125 16-Oct K.ELQAEQEDR[166.11].A "sp|Q00341|VIGLN_HUMAN,tr|A0A024R4E5|A0A024R4E5_HUMAN,tr|H0Y394|H0Y394_HUMAN" 3 1126.513 1.62 58924 5037 2 1126.509131 564.2638 Vigilin OS=Homo sapiens OX=9606 GN=HDLBP PE=1 SV=2 4 1523.5 - 1.02E+06 - - - -3.4354 - 1.675 0.399 - 489.7 1 2 0 -0.0039 9 0 0 0 9.29E+06 5.74E+06 - - - 3.4791 0.9992 221125_WJC_METTL3_EV_vs_WT_F05.05042.05042.2 0.0286 14-Aug K.LTNNISDK.H "sp|Q13207|TBX2_HUMAN,sp|O15119|TBX3_HUMAN" 2 903.4662 0.97 58927 5042 2 903.467112 452.7404 T-box transcription factor TBX2 OS=Homo sapiens OX=9606 GN=TBX2 PE=1 SV=3 5.84 1524 - 5.06E+06 - - - 1.0526 - 1.619 0.32 - 190.6 1 2 0 0.001 8 0 0 0 2.19E+08 2.25E+08 - - - 2.8573 0.9709 221125_WJC_METTL3_EV_vs_WT_F05.05043.05043.2 1.53 18-Oct R.VAGAQIQGAK.E "sp|Q13423|NNTM_HUMAN,tr|D6RHU2|D6RHU2_HUMAN,tr|A0A590UJA4|A0A590UJA4_HUMAN,tr|D6RAI5|D6RAI5_HUMAN,tr|A0A590UK15|A0A590UK15_HUMAN,tr|A0A590UJM2|A0A590UJM2_HUMAN,tr|A0A590UK29|A0A590UK29_HUMAN,tr|A0A590UKC7|A0A590UKC7_HUMAN" 8 941.5294 1.68 58928 5043 2 941.527347 471.772 "NAD(P) transhydrogenase, mitochondrial OS=Homo sapiens OX=9606 GN=NNT PE=1 SV=3" 8.72 1524 - 2.68E+06 - - - -2.2124 - 1.588 0.042 - 197.5 2 2 0 -0.0021 10 0 0 0 6.83E+07 4.08E+07 - - - 0.507 0.983 221125_WJC_METTL3_EV_vs_WT_F05.05045.05045.2 0.375 14-Aug R.VPEEDLK[136.11]R[166.11].T sp|Q99832|TCPH_HUMAN 1 1002.5465 0.01 58930 5045 2 1002.543751 502.2805 T-complex protein 1 subunit eta OS=Homo sapiens OX=9606 GN=CCT7 PE=1 SV=2 4.68 1524.3 - 1.08E+06 - - - -2.7221 - 1.569 0.101 - 223 1 2 0 -0.0027 8 0 0 0 4.08E+05 2.75E+07 - - - 1.1446 0.9964 221125_WJC_METTL3_EV_vs_WT_F05.05047.05047.2 0.000576 16-Sep K.ELQAEQEDR.A "sp|Q00341|VIGLN_HUMAN,tr|A0A024R4E5|A0A024R4E5_HUMAN,tr|H0Y394|H0Y394_HUMAN" 3 1116.5047 1.62 58932 5047 2 1116.500123 559.2596 Vigilin OS=Homo sapiens OX=9606 GN=HDLBP PE=1 SV=2 4 1524.6 - 834524 - - - -4.1272 - 1.579 0.41 - 457.1 1 2 0 -0.0046 9 0 0 0 9.29E+06 5.74E+06 - - - 3.3893 0.9853 221125_WJC_METTL3_EV_vs_WT_F05.05048.05048.2 0.000392 16-Nov R.VVDQQQVER.H "sp|P46100|ATRX_HUMAN,tr|A0A6Q8PHA4|A0A6Q8PHA4_HUMAN" 2 1099.5622 3.91 58933 5048 2 1099.558152 550.7884 Transcriptional regulator ATRX OS=Homo sapiens OX=9606 GN=ATRX PE=1 SV=5 4.37 1524.7 - 537574 - - - -3.6687 - 1.537 0.202 - 324.4 1 2 0 -0.004 9 0 0 0 9.70E+06 2.48E+06 - - - 1.7752 0.9991 221125_WJC_METTL3_EV_vs_WT_F05.05051.05051.2 0.0147 14-Sep K.LTNNISDK[136.11].H "sp|Q13207|TBX2_HUMAN,sp|O15119|TBX3_HUMAN" 2 911.4804 0.97 58934 5051 2 911.478923 456.7475 T-box transcription factor TBX2 OS=Homo sapiens OX=9606 GN=TBX2 PE=1 SV=3 5.84 1525.1 - 1.28E+07 - - - -1.5777 - 1.731 0.307 - 227.2 1 2 0 -0.0014 8 0 0 0 2.16E+08 2.23E+08 - - - 2.9629 0.7719 221125_WJC_METTL3_EV_vs_WT_F05.05052.05052.2 0.409 14-May A.LAEIPGVR.S sp|Q96CN7|ISOC1_HUMAN 1 853.5022 68.8 58935 5052 2 853.50024 427.7584 Isochorismatase domain-containing protein 1 OS=Homo sapiens OX=9606 GN=ISOC1 PE=1 SV=3 6 1525.1 - 4.41E+06 - - - -2.2402 - 1.369 0.267 - 126.7 2 1 0 -0.0019 8 0 0 0 7.01E+07 1.02E+06 - - - 1.8252 0.9946 221125_WJC_METTL3_EV_vs_WT_F05.05054.05054.2 0.049 16-Jul R.IAC[160.03]GPPQAK[136.11].L "sp|Q9Y520|PRC2C_HUMAN,tr|E7EPN9|E7EPN9_HUMAN" 2 948.4942 1.27 58937 5054 2 948.493777 475.2544 Protein PRRC2C OS=Homo sapiens OX=9606 GN=PRRC2C PE=1 SV=4 8.22 1525.2 - 2.35E+06 - - - -0.485 - 1.417 0.137 - 133.9 1 2 0 -0.0005 9 0 0 0 8.08E+07 6.34E+07 - - - 1.0611 0.9992 221125_WJC_METTL3_EV_vs_WT_F05.05056.05056.2 0.494 14-Jun R.EATEQEIR[166.11].S "sp|Q9BWF3|RBM4_HUMAN,sp|Q9BQ04|RBM4B_HUMAN,tr|E9PM61|E9PM61_HUMAN,tr|D6R9K7|D6R9K7_HUMAN,tr|J3QRR5|J3QRR5_HUMAN,tr|E9PB51|E9PB51_HUMAN,tr|U3KQD5|U3KQD5_HUMAN,tr|E9PLB0|E9PLB0_HUMAN" 8 984.4752 1.46 58939 5056 2 984.475167 493.2449 RNA-binding protein 4 OS=Homo sapiens OX=9606 GN=RBM4 PE=1 SV=1 4.25 1525.4 - 1.64E+06 - - - 0.0081 - 1.677 0.269 - 270.3 1 2 0 0 8 0 0 0 2.64E+09 1.81E+09 - - - 2.5871 0.9989 221125_WJC_METTL3_EV_vs_WT_F05.05061.05061.2 0.0113 18-Sep R.VAGAQIQGAK[136.11].E "sp|Q13423|NNTM_HUMAN,tr|D6RHU2|D6RHU2_HUMAN,tr|A0A590UJA4|A0A590UJA4_HUMAN,tr|D6RAI5|D6RAI5_HUMAN,tr|A0A590UK15|A0A590UK15_HUMAN,tr|A0A590UJM2|A0A590UJM2_HUMAN,tr|A0A590UK29|A0A590UK29_HUMAN,tr|A0A590UKC7|A0A590UKC7_HUMAN" 8 949.5436 1.68 58942 5061 2 949.542921 475.7791 "NAD(P) transhydrogenase, mitochondrial OS=Homo sapiens OX=9606 GN=NNT PE=1 SV=3" 8.72 1525.9 - 3.44E+06 - - - -0.7467 - 1.597 0.275 - 220.9 1 2 0 -0.0007 10 0 0 0 6.83E+07 4.08E+07 - - - 2.3786 0.9948 221125_WJC_METTL3_EV_vs_WT_F05.05062.05062.2 0.148 14-Aug R.YGQIQQAK.S sp|Q15699|ALX1_HUMAN 1 934.4872 1.65 58943 5062 2 934.489425 468.2509 ALX homeobox protein 1 OS=Homo sapiens OX=9606 GN=ALX1 PE=1 SV=2 8.59 1526 - 2.26E+06 - - - 2.3489 - 1.425 0.241 - 155.4 1 2 0 0.0022 8 0 0 0 2.75E+07 1.67E+07 - - - 1.8885 0.9363 221125_WJC_METTL3_EV_vs_WT_F05.05070.05070.2 5.48 12-Jun K.DQGELER.Q sp|P35579|MYH9_HUMAN 1 845.3879 0.92 58948 5070 2 845.387615 423.7012 Myosin-9 OS=Homo sapiens OX=9606 GN=MYH9 PE=1 SV=4 4.14 1526.8 - 1.35E+07 - - - -0.349 - 1.03 0.037 - 168.6 1 2 0 -0.0003 7 0 0 0 2.11E+08 2.29E+08 - - - -0.5922 0.9982 221125_WJC_METTL3_EV_vs_WT_F05.05071.05071.2 0.00657 16-Jul K.EGIPPDQQR[166.11].L "sp|P62979|RS27A_HUMAN,sp|P0CG48|UBC_HUMAN,sp|P0CG48|UBC_HUMAN,sp|P0CG48|UBC_HUMAN,sp|P0CG48|UBC_HUMAN,sp|P0CG48|UBC_HUMAN,sp|P0CG48|UBC_HUMAN,sp|P0CG48|UBC_HUMAN,sp|P0CG48|UBC_HUMAN,sp|P0CG48|UBC_HUMAN,sp|P0CG47|UBB_HUMAN,sp|P0CG47|UBB_HUMAN,sp|P0CG47|UBB_HUMAN,sp|P62987|RL40_HUMAN,tr|F5H388|F5H388_HUMAN,tr|F5H388|F5H388_HUMAN,tr|F5GYU3|F5GYU3_HUMAN,tr|F5GYU3|F5GYU3_HUMAN,tr|B4DV12|B4DV12_HUMAN,tr|B4DV12|B4DV12_HUMAN,tr|J3QSA3|J3QSA3_HUMAN,tr|Q5PY61|Q5PY61_HUMAN,tr|Q5PY61|Q5PY61_HUMAN,tr|Q5PY61|Q5PY61_HUMAN,tr|F5H2Z3|F5H2Z3_HUMAN,tr|F5H2Z3|F5H2Z3_HUMAN,tr|M0R2S1|M0R2S1_HUMAN,tr|J3QS39|J3QS39_HUMAN,tr|J3QTR3|J3QTR3_HUMAN,tr|Q96C32|Q96C32_HUMAN,tr|Q96C32|Q96C32_HUMAN,tr|Q96C32|Q96C32_HUMAN,tr|Q96C32|Q96C32_HUMAN,tr|M0R1V7|M0R1V7_HUMAN,tr|F5H747|F5H747_HUMAN,tr|F5H747|F5H747_HUMAN,tr|F5GXK7|F5GXK7_HUMAN,tr|F5GXK7|F5GXK7_HUMAN,tr|M0R1M6|M0R1M6_HUMAN,tr|F5H6Q2|F5H6Q2_HUMAN,tr|F5H6Q2|F5H6Q2_HUMAN,tr|F5GZ39|F5GZ39_HUMAN,tr|J3QKN0|J3QKN0_HUMAN,tr|J3QKN0|J3QKN0_HUMAN,tr|J3QKN0|J3QKN0_HUMAN,tr|F5H265|F5H265_HUMAN,tr|F5H265|F5H265_HUMAN,tr|A0A2R8Y422|A0A2R8Y422_HUMAN" 48 1048.5177 0.68 58949 5071 2 1048.519377 525.2661 Ubiquitin-40S ribosomal protein S27a OS=Homo sapiens OX=9606 GN=RPS27A PE=1 SV=2 4.37 1526.9 - 1.21E+06 - - - 1.6061 - 1.394 0.324 - 169.1 1 2 0 0.0017 9 0 0 0 4.40E+08 6.48E+08 - - - 2.3945 0.9983 221125_WJC_METTL3_EV_vs_WT_F05.05076.05076.2 0.000902 16-Sep R.FDSDAASQR.M "sp|P04439|HLAA_HUMAN,tr|A0A140T941|A0A140T941_HUMAN,tr|A0A1W2PQS8|A0A1W2PQS8_HUMAN,tr|A0A140T8W8|A0A140T8W8_HUMAN,tr|Q9GJ45|Q9GJ45_HUMAN,tr|Q53Z42|Q53Z42_HUMAN,tr|Q5RJ27|Q5RJ27_HUMAN,tr|Q5SRN5|Q5SRN5_HUMAN,tr|A0A1W2PS24|A0A1W2PS24_HUMAN,tr|A0A140T955|A0A140T955_HUMAN,tr|A0A0G2JPD3|A0A0G2JPD3_HUMAN,tr|A0A140T913|A0A140T913_HUMAN,tr|A0A1W2PPQ2|A0A1W2PPQ2_HUMAN,tr|Q5SPM2|Q5SPM2_HUMAN,tr|A0A140T8Y4|A0A140T8Y4_HUMAN,tr|A0A140T975|A0A140T975_HUMAN,tr|A0A140T933|A0A140T933_HUMAN,tr|A0A1W2PRT9|A0A1W2PRT9_HUMAN,tr|A0A1W2PPF8|A0A1W2PPF8_HUMAN,tr|Q5SRN7|Q5SRN7_HUMAN,tr|A0A1W2PR61|A0A1W2PR61_HUMAN,tr|A0A140T9I0|A0A140T9I0_HUMAN,tr|A0A140T9X5|A0A140T9X5_HUMAN,tr|A0A1W2PS39|A0A1W2PS39_HUMAN,tr|A0A140T9Z6|A0A140T9Z6_HUMAN,tr|B0UXQ0|B0UXQ0_HUMAN" 26 995.4308 0.4 58952 5076 2 995.426567 498.7227 "HLA class I histocompatibility antigen, A alpha chain OS=Homo sapiens OX=9606 GN=HLA-A PE=1 SV=2" 4.21 1527.4 - 648757 - - - -4.2906 - 1.953 0.477 - 280.2 1 2 0 -0.0043 9 0 0 0 1.33E+07 3.32E+07 - - - 4.4993 0.9984 221125_WJC_METTL3_EV_vs_WT_F05.05077.05077.2 0.187 12-Jul K.DQGELER[166.11].Q sp|P35579|MYH9_HUMAN 1 855.3962 0.92 58953 5077 2 855.395734 428.7054 Myosin-9 OS=Homo sapiens OX=9606 GN=MYH9 PE=1 SV=4 4.14 1527.5 - 1.47E+07 - - - -0.5214 - 1.447 0.243 - 301.5 1 2 0 -0.0004 7 0 0 0 2.11E+08 2.29E+08 - - - 2.0064 0.9997 221125_WJC_METTL3_EV_vs_WT_F05.05080.05080.2 2.38E-05 18-Sep R.AGYAGEDC[160.03]PK[136.11].V "sp|O96019|ACL6A_HUMAN,sp|O94805|ACL6B_HUMAN,tr|H7C5S0|H7C5S0_HUMAN" 3 1074.4532 0.46 58956 5080 2 1074.454822 538.2339 Actin-like protein 6A OS=Homo sapiens OX=9606 GN=ACTL6A PE=1 SV=1 4.37 1527.8 - 434050 - - - 1.5468 - 1.684 0.538 - 214.3 1 2 0 0.0017 10 0 0 0 6.01E+06 1.29E+07 - - - 4.4689 0.9991 221125_WJC_METTL3_EV_vs_WT_F05.05085.05085.2 1.01 14-Aug R.EATEQEIR.S "sp|Q9BWF3|RBM4_HUMAN,sp|Q9BQ04|RBM4B_HUMAN,tr|E9PM61|E9PM61_HUMAN,tr|D6R9K7|D6R9K7_HUMAN,tr|J3QRR5|J3QRR5_HUMAN,tr|E9PB51|E9PB51_HUMAN,tr|U3KQD5|U3KQD5_HUMAN,tr|E9PLB0|E9PLB0_HUMAN" 8 974.4669 1.46 58959 5085 2 974.466042 488.2407 RNA-binding protein 4 OS=Homo sapiens OX=9606 GN=RBM4 PE=1 SV=1 4.25 1528.4 - 1.53E+08 - - - -0.8692 - 1.672 0.27 - 469.2 1 2 0 -0.0008 8 0 0 0 2.64E+09 1.81E+09 - - - 2.5852 0.9985 221125_WJC_METTL3_EV_vs_WT_F05.05089.05089.2 0.152 14-Aug K.ASQLVSEK[136.11].V sp|Q99961|SH3G1_HUMAN 1 868.4745 1.63 58963 5089 2 868.474203 435.2445 Endophilin-A2 OS=Homo sapiens OX=9606 GN=SH3GL1 PE=1 SV=1 6.05 1528.6 - 4.65E+06 - - - -0.3961 - 1.67 0.197 - 343.2 1 2 0 -0.0003 8 0 0 0 2.11E+08 1.30E+08 - - - 2.0426 0.9984 221125_WJC_METTL3_EV_vs_WT_F05.05092.05092.2 0.016 18-Oct K.TVSEVSEQPK[136.11].E sp|Q9UKJ3|GPTC8_HUMAN 1 1110.5648 1.06 58966 5092 2 1110.563395 556.2897 G patch domain-containing protein 8 OS=Homo sapiens OX=9606 GN=GPATCH8 PE=1 SV=2 4.53 1529 - 635624 - - - -1.2822 - 1.496 0.277 - 110 1 2 0 -0.0014 10 0 0 0 1.01E+07 9.60E+06 - - - 2.2108 0.9973 221125_WJC_METTL3_EV_vs_WT_F05.05097.05097.2 0.775 14-Jul K.ASQLVSEK.V sp|Q99961|SH3G1_HUMAN 1 860.4603 1.63 58969 5097 2 860.459196 431.2374 Endophilin-A2 OS=Homo sapiens OX=9606 GN=SH3GL1 PE=1 SV=1 6.05 1529.6 - 1.17E+07 - - - -1.3377 - 1.651 0.172 - 294.1 1 2 0 -0.0012 8 0 0 0 2.11E+08 1.30E+08 - - - 1.8232 0.9989 221125_WJC_METTL3_EV_vs_WT_F05.05101.05101.2 0.00398 18-Sep K.AESALAQQAK.H sp|Q99661|KIF2C_HUMAN 1 1015.5298 0.76 58973 5101 2 1015.528779 508.7722 Kinesin-like protein KIF2C OS=Homo sapiens OX=9606 GN=KIF2C PE=1 SV=2 6.05 1529.8 - 1.08E+06 - - - -1.029 - 1.482 0.317 - 247.6 1 2 0 -0.001 10 0 0 0 1.04E+07 1.37E+07 - - - 2.4801 0.8301 221125_WJC_METTL3_EV_vs_WT_F05.05102.05102.2 0.411 18-Sep R.QLEMSAEAER[166.11].L sp|Q15149|PLEC_HUMAN 1 1172.5371 1.34 58974 5102 2 1172.54809 587.2758 Plectin OS=Homo sapiens OX=9606 GN=PLEC PE=1 SV=3 4.25 1530 - 599614 - - - 9.3669 - 1.802 0.195 - 221.5 2 2 0 0.011 10 0 0 0 9.00E+06 6.72E+06 - - - 1.9871 0.9994 221125_WJC_METTL3_EV_vs_WT_F05.05103.05103.2 0.00765 18-Jul K.VTC[160.03]QSSELAK.D sp|Q09328|MGT5A_HUMAN 1 1121.5387 0.69 58975 5103 2 1121.539462 561.7766 "Alpha-1,6-mannosylglycoprotein 6-beta-N-acetylglucosaminyltransferase A OS=Homo sapiens OX=9606 GN=MGAT5 PE=1 SV=1" 5.97 1530.1 - 301941 - - - 0.7026 - 1.667 0.345 - 156 1 2 0 0.0008 10 0 0 0 3.96E+06 5.77E+06 - - - 3.0154 0.9975 221125_WJC_METTL3_EV_vs_WT_F05.05107.05107.2 0.0282 12-Sep R.EHTALLK[136.11].L "sp|P18077|RL35A_HUMAN,tr|F8WB72|F8WB72_HUMAN,tr|C9K025|C9K025_HUMAN,tr|F8WBS5|F8WBS5_HUMAN" 4 818.4742 0.65 58977 5107 2 818.472218 410.2444 60S ribosomal protein L35a OS=Homo sapiens OX=9606 GN=RPL35A PE=1 SV=2 6.85 1530.5 - 4.49E+06 - - - -2.3642 - 1.423 0.311 - 411.1 1 2 0 -0.0019 7 0 0 0 5.06E+07 7.76E+07 - - - 2.4552 0.9994 221125_WJC_METTL3_EV_vs_WT_F05.05108.05108.2 0.00325 14-Aug R.VFTTNNGR[166.11].H "sp|O00422|SAP18_HUMAN,tr|U3KQ12|U3KQ12_HUMAN,tr|U3KPY7|U3KPY7_HUMAN,tr|H7BZW6|H7BZW6_HUMAN" 4 917.4594 1.37 58978 5108 2 917.458873 459.737 Histone deacetylase complex subunit SAP18 OS=Homo sapiens OX=9606 GN=SAP18 PE=1 SV=1 9.72 1530.6 - 5.23E+06 - - - -0.6278 - 1.469 0.371 - 227.4 1 2 0 -0.0006 8 0 0 0 2.12E+08 1.55E+08 - - - 2.9409 0.999 221125_WJC_METTL3_EV_vs_WT_F05.05109.05109.2 0.0177 14-Aug R.VFTTNNGR.H "sp|O00422|SAP18_HUMAN,tr|U3KQ12|U3KQ12_HUMAN,tr|U3KPY7|U3KPY7_HUMAN,tr|H7BZW6|H7BZW6_HUMAN" 4 907.4512 1.36 58979 5109 2 907.449335 454.7329 Histone deacetylase complex subunit SAP18 OS=Homo sapiens OX=9606 GN=SAP18 PE=1 SV=1 9.72 1530.6 - 5.06E+06 - - - -2.0321 - 1.496 0.39 - 212.6 1 2 0 -0.0018 8 0 0 0 2.13E+08 1.57E+08 - - - 3.1358 0.9992 221125_WJC_METTL3_EV_vs_WT_F05.05113.05113.2 0.00668 18-Aug R.AGYAGEDC[160.03]PK.V "sp|O96019|ACL6A_HUMAN,sp|O94805|ACL6B_HUMAN,tr|H7C5S0|H7C5S0_HUMAN" 3 1066.439 0.55 58983 5113 2 1066.440361 534.2268 Actin-like protein 6A OS=Homo sapiens OX=9606 GN=ACTL6A PE=1 SV=1 4.37 1531 - 383750 - - - 1.3137 - 1.378 0.416 - 152.2 1 2 0 0.0014 10 0 0 0 6.01E+06 1.10E+07 - - - 3.0081 0.9967 221125_WJC_METTL3_EV_vs_WT_F05.05116.05116.2 0.0333 16-Jun K.EGIPPDQQR.L "sp|P62979|RS27A_HUMAN,sp|P0CG48|UBC_HUMAN,sp|P0CG48|UBC_HUMAN,sp|P0CG48|UBC_HUMAN,sp|P0CG48|UBC_HUMAN,sp|P0CG48|UBC_HUMAN,sp|P0CG48|UBC_HUMAN,sp|P0CG48|UBC_HUMAN,sp|P0CG48|UBC_HUMAN,sp|P0CG48|UBC_HUMAN,sp|P0CG47|UBB_HUMAN,sp|P0CG47|UBB_HUMAN,sp|P0CG47|UBB_HUMAN,sp|P62987|RL40_HUMAN,tr|F5H388|F5H388_HUMAN,tr|F5H388|F5H388_HUMAN,tr|F5GYU3|F5GYU3_HUMAN,tr|F5GYU3|F5GYU3_HUMAN,tr|B4DV12|B4DV12_HUMAN,tr|B4DV12|B4DV12_HUMAN,tr|J3QSA3|J3QSA3_HUMAN,tr|Q5PY61|Q5PY61_HUMAN,tr|Q5PY61|Q5PY61_HUMAN,tr|Q5PY61|Q5PY61_HUMAN,tr|F5H2Z3|F5H2Z3_HUMAN,tr|F5H2Z3|F5H2Z3_HUMAN,tr|M0R2S1|M0R2S1_HUMAN,tr|J3QS39|J3QS39_HUMAN,tr|J3QTR3|J3QTR3_HUMAN,tr|Q96C32|Q96C32_HUMAN,tr|Q96C32|Q96C32_HUMAN,tr|Q96C32|Q96C32_HUMAN,tr|Q96C32|Q96C32_HUMAN,tr|M0R1V7|M0R1V7_HUMAN,tr|F5H747|F5H747_HUMAN,tr|F5H747|F5H747_HUMAN,tr|F5GXK7|F5GXK7_HUMAN,tr|F5GXK7|F5GXK7_HUMAN,tr|M0R1M6|M0R1M6_HUMAN,tr|F5H6Q2|F5H6Q2_HUMAN,tr|F5H6Q2|F5H6Q2_HUMAN,tr|F5GZ39|F5GZ39_HUMAN,tr|J3QKN0|J3QKN0_HUMAN,tr|J3QKN0|J3QKN0_HUMAN,tr|J3QKN0|J3QKN0_HUMAN,tr|F5H265|F5H265_HUMAN,tr|F5H265|F5H265_HUMAN,tr|A0A2R8Y422|A0A2R8Y422_HUMAN" 48 1038.5094 0.67 58984 5116 2 1038.508561 520.262 Ubiquitin-40S ribosomal protein S27a OS=Homo sapiens OX=9606 GN=RPS27A PE=1 SV=2 4.37 1531.4 - 3.80E+06 - - - -0.83 - 1.236 0.249 - 124 1 2 0 -0.0009 9 0 0 0 4.48E+08 6.73E+08 - - - 1.4928 0.999 221125_WJC_METTL3_EV_vs_WT_F05.05122.05122.2 0.00444 18-Aug K.VTC[160.03]QSSELAK[136.11].D sp|Q09328|MGT5A_HUMAN 1 1129.5529 0.69 58990 5122 2 1129.551955 565.7837 "Alpha-1,6-mannosylglycoprotein 6-beta-N-acetylglucosaminyltransferase A OS=Homo sapiens OX=9606 GN=MGAT5 PE=1 SV=1" 5.97 1532 - 561531 - - - -0.8136 - 1.397 0.342 - 219.7 1 2 0 -0.0009 10 0 0 0 3.96E+06 5.77E+06 - - - 2.4999 0.9455 221125_WJC_METTL3_EV_vs_WT_F05.05126.05126.2 1.95 12-Jun R.ISAPQER.L "sp|P61163|ACTZ_HUMAN,sp|P42025|ACTY_HUMAN" 2 799.4188 0.53 58992 5126 2 799.417446 400.7167 Alpha-centractin OS=Homo sapiens OX=9606 GN=ACTR1A PE=1 SV=1 6 1532.4 - 3.91E+06 - - - -1.715 - 1.224 0.025 - 110.7 1 2 0 -0.0014 7 0 0 0 7.57E+07 1.44E+08 - - - -0.1343 0.9997 221125_WJC_METTL3_EV_vs_WT_F05.05128.05128.2 0.000138 16-Aug R.SLHQTTVIK.A "sp|Q14774|HLX_HUMAN,tr|F8VWZ5|F8VWZ5_HUMAN" 2 1025.5869 1.33 58994 5128 2 1025.585442 513.8007 H2.0-like homeobox protein OS=Homo sapiens OX=9606 GN=HLX PE=1 SV=3 8.49 1532.5 - 1.79E+06 - - - -1.4655 - 1.895 0.423 - 203.1 1 2 0 -0.0015 9 0 0 0 2.17E+07 1.63E+07 - - - 4.0141 0.9997 221125_WJC_METTL3_EV_vs_WT_F05.05129.05129.2 0.000372 18-Oct R.EVTSPNSTVR[166.11].K "sp|Q9Y4A5|TRRAP_HUMAN,tr|H0Y4W2|H0Y4W2_HUMAN,tr|F2Z2U4|F2Z2U4_HUMAN" 3 1098.5545 1.42 58995 5129 2 1098.553736 550.2845 Transformation\transcription domain-associated protein OS=Homo sapiens OX=9606 GN=TRRAP PE=1 SV=3 6.1 1532.6 - 1.42E+06 - - - -0.67 - 1.795 0.418 - 407.6 1 2 0 -0.0007 10 0 0 0 5.06E+07 3.55E+07 - - - 3.761 0.9997 221125_WJC_METTL3_EV_vs_WT_F05.05135.05135.2 0.00024 14-Oct K.LYNNHEIR[166.11].S "sp|O60506|HNRPQ_HUMAN,tr|A0A7I2YQN2|A0A7I2YQN2_HUMAN,tr|A0A7I2V5Q6|A0A7I2V5Q6_HUMAN,tr|A0A7I2V4Z0|A0A7I2V4Z0_HUMAN,tr|B7Z645|B7Z645_HUMAN,tr|A0A7I2V2F2|A0A7I2V2F2_HUMAN,tr|A0A7I2V346|A0A7I2V346_HUMAN,tr|A0A7I2V309|A0A7I2V309_HUMAN" 8 1067.5388 1.36 59001 5135 2 1067.537423 534.7767 Heterogeneous nuclear ribonucleoprotein Q OS=Homo sapiens OX=9606 GN=SYNCRIP PE=1 SV=2 6.75 1533.2 - 438473 - - - -1.2543 - 1.774 0.411 - 370.1 1 2 0 -0.0013 8 0 0 0 4.26E+07 3.13E+07 - - - 3.8051 0.9995 221125_WJC_METTL3_EV_vs_WT_F05.05138.05138.2 0.000119 16-Sep K.TTAAFQQGK[136.11].L "sp|P09234|RU1C_HUMAN,tr|A0A0A0MRR7|A0A0A0MRR7_HUMAN,tr|Q5TAL2|Q5TAL2_HUMAN" 3 958.4963 0.97 59002 5138 2 958.495679 480.2554 U1 small nuclear ribonucleoprotein C OS=Homo sapiens OX=9606 GN=SNRPC PE=1 SV=1 8.41 1533.6 - 3.70E+07 - - - -0.6948 - 1.696 0.346 - 350.4 1 2 0 -0.0007 9 0 0 0 4.91E+08 5.09E+08 - - - 3.1247 0.9988 221125_WJC_METTL3_EV_vs_WT_F05.05139.05139.2 0.0326 16-Aug K.VEGITNQGK.K "sp|Q9P2E9|RRBP1_HUMAN,tr|A0A087WVV2|A0A087WVV2_HUMAN,tr|V9GY78|V9GY78_HUMAN" 3 944.4927 1.59 59003 5139 2 944.491789 473.2536 Ribosome-binding protein 1 OS=Homo sapiens OX=9606 GN=RRBP1 PE=1 SV=5 5.97 1533.6 - 7.88E+06 - - - -0.9751 - 1.426 0.312 - 193.4 1 2 0 -0.0009 9 0 0 0 1.26E+08 7.96E+07 - - - 2.3718 0.9937 221125_WJC_METTL3_EV_vs_WT_F05.05141.05141.2 0.0795 12-Jul R.HLPGVC[160.03]K.V "sp|Q96HS1|PGAM5_HUMAN,tr|F5GXG4|F5GXG4_HUMAN" 2 809.4218 0.34 59005 5141 2 809.423177 405.7182 "Serine\threonine-protein phosphatase PGAM5, mitochondrial OS=Homo sapiens OX=9606 GN=PGAM5 PE=1 SV=2" 8.23 1533.7 - 4.97E+06 - - - 1.7086 - 1.324 0.201 - 213.4 1 2 0 0.0014 7 0 0 0 9.28E+07 2.73E+08 - - - 1.4144 0.9996 221125_WJC_METTL3_EV_vs_WT_F05.05143.05143.2 0.0153 16-Oct R.SQLEEQAAR.S sp|Q6KB66|K2C80_HUMAN 1 1030.5043 2.17 59007 5143 2 1030.504114 516.2594 "Keratin, type II cytoskeletal 80 OS=Homo sapiens OX=9606 GN=KRT80 PE=1 SV=2" 4.53 1533.8 - 2.12E+06 - - - -0.2164 - 2.016 0.304 - 513.5 1 2 0 -0.0002 9 0 0 0 1.22E+08 5.60E+07 - - - 3.3146 0.889 221125_WJC_METTL3_EV_vs_WT_F05.05145.05145.2 0.682 16-Jun K.C[160.03]QGGVNPVR[166.11].E sp|Q99523|SORT_HUMAN 1 995.4846 206.41 59009 5145 2 995.485929 498.7496 Sortilin OS=Homo sapiens OX=9606 GN=SORT1 PE=1 SV=3 8.25 1534 - 427208 - - - 1.3159 - 1.189 0.004 - 105.5 4 2 0 0.0013 9 0 0 0 7.83E+08 3.79E+06 - - - -0.698 0.995 221125_WJC_METTL3_EV_vs_WT_F05.05148.05148.2 1.17 14-Aug K.SVLADQGK.S "sp|Q9NYF8|BCLF1_HUMAN,tr|E9PKI6|E9PKI6_HUMAN,tr|A0A1W2PQ43|A0A1W2PQ43_HUMAN,tr|E9PK91|E9PK91_HUMAN,tr|E9PK09|E9PK09_HUMAN,tr|E9PQN2|E9PQN2_HUMAN" 6 816.4341 1.13 59010 5148 2 816.433796 409.2243 Bcl-2-associated transcription factor 1 OS=Homo sapiens OX=9606 GN=BCLAF1 PE=1 SV=2 5.55 1534.4 - 8.60E+06 - - - -0.4115 - 1.223 0.199 - 197.9 1 2 0 -0.0003 8 0 0 0 4.61E+08 4.08E+08 - - - 1.1178 0.9808 221125_WJC_METTL3_EV_vs_WT_F05.05150.05150.2 1.75 14-Jun K.K[136.11]EKPQGQR[166.11].E "sp|Q9HC35|EMAL4_HUMAN,tr|B5MBZ0|B5MBZ0_HUMAN" 2 987.558 - 59012 5150 2 987.557245 494.7863 Echinoderm microtubule-associated protein-like 4 OS=Homo sapiens OX=9606 GN=EML4 PE=1 SV=3 9.99 1534.5 - 6.58E+06 - - - -0.8131 - 1.191 0.093 - 145.8 1 2 0 -0.0008 8 0 0 0 - - - - - 0.2548 0.9958 221125_WJC_METTL3_EV_vs_WT_F05.05152.05152.2 0.28 14-Jul K.KEKPQGQR.E "sp|Q9HC35|EMAL4_HUMAN,tr|B5MBZ0|B5MBZ0_HUMAN" 2 969.5356 16.51 59014 5152 2 969.535123 485.7751 Echinoderm microtubule-associated protein-like 4 OS=Homo sapiens OX=9606 GN=EML4 PE=1 SV=3 9.99 1534.6 - 5.66E+06 - - - -0.4693 - 1.308 0.189 - 202.9 1 2 0 -0.0005 8 0 0 0 2.63E+08 1.59E+07 - - - 1.2466 0.9774 221125_WJC_METTL3_EV_vs_WT_F05.05157.05157.2 0.00711 12-Jul H.C[160.03]QYVTEK.V "sp|P05062|ALDOB_HUMAN,sp|P04075|ALDOA_HUMAN,sp|P09972|ALDOC_HUMAN,tr|H3BQN4|H3BQN4_HUMAN,tr|A0A3B3IS80|A0A3B3IS80_HUMAN,tr|J3KPS3|J3KPS3_HUMAN,tr|A0A087WXX2|A0A087WXX2_HUMAN,tr|H3BPS8|H3BPS8_HUMAN" 8 926.4168 1.41 59017 5157 2 926.416362 464.2157 Fructose-bisphosphate aldolase B OS=Homo sapiens OX=9606 GN=ALDOB PE=1 SV=2 5.99 1535.1 - 2.53E+06 - - - -0.4382 - 1.615 0.373 - 350.5 1 1 0 -0.0004 7 0 0 0 6.48E+07 4.61E+07 - - - 3.3146 0.9975 221125_WJC_METTL3_EV_vs_WT_F05.05168.05168.2 0.00879 16-Jun K.EMQPTHPIR[166.11].L "sp|P31946|1433B_HUMAN,sp|P27348|1433T_HUMAN,sp|P63104|1433Z_HUMAN,tr|H0YB80|H0YB80_HUMAN,tr|E7EX29|E7EX29_HUMAN,tr|B7Z2E6|B7Z2E6_HUMAN,tr|B0AZS6|B0AZS6_HUMAN" 7 1117.5578 1.48 59024 5168 2 1117.557305 559.7862 14-3-3 protein beta\alpha OS=Homo sapiens OX=9606 GN=YWHAB PE=1 SV=3 6.85 1536.2 - 413773 - - - -0.4277 - 1.238 0.268 - 124.6 1 2 0 -0.0005 9 0 0 0 6.16E+06 4.15E+06 - - - 1.638 0.9997 221125_WJC_METTL3_EV_vs_WT_F05.05171.05171.2 0.0201 18-Sep K.ASGVQAQMAK.Q "sp|Q15434|RBMS2_HUMAN,sp|P29558|RBMS1_HUMAN,tr|E7ETU5|E7ETU5_HUMAN,tr|F6Y5H0|F6Y5H0_HUMAN,tr|E7EPF2|E7EPF2_HUMAN,tr|F8W1T6|F8W1T6_HUMAN" 6 989.4964 1.3 59025 5171 2 989.496213 495.7555 "RNA-binding motif, single-stranded-interacting protein 2 OS=Homo sapiens OX=9606 GN=RBMS2 PE=1 SV=1" 8.8 1536.6 - 1.47E+07 - - - -0.2041 - 1.856 0.374 - 367.1 1 2 0 -0.0002 10 0 0 0 3.90E+08 2.99E+08 - - - 3.5295 0.9979 221125_WJC_METTL3_EV_vs_WT_F05.05176.05176.2 1.12 12-Aug K.K[136.11]QLDSLR[166.11].E "sp|Q86U44|MTA70_HUMAN,tr|B4E349|B4E349_HUMAN,tr|F5H6D8|F5H6D8_HUMAN,tr|B4DTN4|B4DTN4_HUMAN" 4 876.5148 0.03 59028 5176 2 876.51376 439.2647 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 8.75 1537.1 - 5.11E+06 - - - -1.1705 - 1.825 0.135 - 306.8 1 2 0 -0.001 7 0 0 0 6.90E+07 2.40E+09 - - - 1.9439 0.9871 221125_WJC_METTL3_EV_vs_WT_F05.05177.05177.2 1.41 12-Jul R.FTDEESR.V "sp|Q9NYF8|BCLF1_HUMAN,tr|H0YF00|H0YF00_HUMAN,tr|E9PKI6|E9PKI6_HUMAN,tr|A0A1W2PQ43|A0A1W2PQ43_HUMAN,tr|E9PK91|E9PK91_HUMAN,tr|E9PK09|E9PK09_HUMAN,tr|E9PQN2|E9PQN2_HUMAN" 7 882.3719 3.19 59029 5177 2 882.372901 442.1932 Bcl-2-associated transcription factor 1 OS=Homo sapiens OX=9606 GN=BCLAF1 PE=1 SV=2 4.14 1537.2 - 672217 - - - 1.105 - 1.129 0.168 - 175.4 1 2 0 0.001 7 0 0 0 1.23E+07 3.86E+06 - - - 0.666 0.9821 221125_WJC_METTL3_EV_vs_WT_F05.05179.05179.2 0.000426 13/22 K.PAESSAVAATEK.K sp|O95182|NDUA7_HUMAN 1 1159.5721 1.89 59031 5179 2 1159.575045 580.7933 NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 7 OS=Homo sapiens OX=9606 GN=NDUFA7 PE=1 SV=3 4.53 1537.4 - 504221 - - - 2.5553 - 2.672 0.518 - 532.8 1 1 0 0.003 12 0 0 0 6.77E+06 3.58E+06 - - - 5.452 0.9971 221125_WJC_METTL3_EV_vs_WT_F05.05184.05184.2 0.223 16-Oct K.TTAAFQQGK.L "sp|P09234|RU1C_HUMAN,tr|A0A0A0MRR7|A0A0A0MRR7_HUMAN,tr|Q5TAL2|Q5TAL2_HUMAN" 3 950.4821 0.96 59034 5184 2 950.479277 476.2483 U1 small nuclear ribonucleoprotein C OS=Homo sapiens OX=9606 GN=SNRPC PE=1 SV=1 8.41 1537.9 - 3.70E+06 - - - -3.0174 - 1.747 0.286 - 454.6 1 2 0 -0.0029 9 0 0 0 4.91E+08 5.13E+08 - - - 2.7665 0.9927 221125_WJC_METTL3_EV_vs_WT_F05.05186.05186.2 0.0762 16-Jul R.SAVPPGADK[136.11].K "sp|P46783|RS10_HUMAN,tr|F6U211|F6U211_HUMAN,tr|A0A1W2PQS6|A0A1W2PQS6_HUMAN,tr|A0A2R8YFH6|A0A2R8YFH6_HUMAN,tr|A0A2R8Y7H1|A0A2R8Y7H1_HUMAN,tr|S4R435|S4R435_HUMAN" 6 848.4483 1.28 59035 5186 2 848.446887 425.2314 40S ribosomal protein S10 OS=Homo sapiens OX=9606 GN=RPS10 PE=1 SV=1 5.55 1538.2 - 6.45E+06 - - - -1.7031 - 1.181 0.232 - 161.8 1 2 0 -0.0014 9 0 0 0 3.71E+08 2.90E+08 - - - 1.2354 0.999 221125_WJC_METTL3_EV_vs_WT_F05.05190.05190.2 0.012 12-Jul R.NVESYTK[136.11].L "sp|P04843|RPN1_HUMAN,tr|B7Z4L4|B7Z4L4_HUMAN" 2 847.4167 1.23 59038 5190 2 847.41585 424.7156 Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit 1 OS=Homo sapiens OX=9606 GN=RPN1 PE=1 SV=1 6 1538.5 - 8.03E+06 - - - -1.0007 - 1.421 0.319 - 177.8 1 2 0 -0.0008 7 0 0 0 1.69E+08 1.38E+08 - - - 2.5102 0.9984 221125_WJC_METTL3_EV_vs_WT_F05.05191.05191.2 0.107 12-Nov K.RLDAAYR.S "sp|Q9Y5A9|YTHD2_HUMAN,sp|Q7Z739|YTHD3_HUMAN,tr|A0A087X0Q1|A0A087X0Q1_HUMAN,tr|A0A024R7W5|A0A024R7W5_HUMAN,tr|A0A087WY31|A0A087WY31_HUMAN" 5 863.4614 1.28 59039 5191 2 863.459544 432.738 YTH domain-containing family protein 2 OS=Homo sapiens OX=9606 GN=YTHDF2 PE=1 SV=2 8.75 1538.6 - 5.51E+06 - - - -2.0916 - 2.073 0.181 - 459.1 1 2 0 -0.0018 7 0 0 0 7.03E+08 5.49E+08 - - - 2.6872 0.9762 221125_WJC_METTL3_EV_vs_WT_F05.05193.05193.2 3.5 12-Jul R.SEIINSK[136.11].N "sp|Q9BTV4|TMM43_HUMAN,tr|A0A590UK62|A0A590UK62_HUMAN" 2 797.4374 1.72 59041 5193 2 797.43737 399.726 Transmembrane protein 43 OS=Homo sapiens OX=9606 GN=TMEM43 PE=1 SV=1 5.72 1538.8 - 1.16E+06 - - - -0.079 - 1.308 0.02 - 234.5 1 2 0 -0.0001 7 0 0 0 3.34E+07 1.94E+07 - - - 0.0395 0.9986 221125_WJC_METTL3_EV_vs_WT_F05.05196.05196.2 0.155 14-Jul R.LSNC[160.03]GYGR[166.11].R sp|Q5JSZ5|PRC2B_HUMAN 1 935.4159 1.76 59042 5196 2 935.413806 468.7152 Protein PRRC2B OS=Homo sapiens OX=9606 GN=PRRC2B PE=1 SV=2 8.22 1539.2 - 3.16E+06 - - - -2.2065 - 1.61 0.328 - 167.7 1 2 0 -0.0021 8 0 0 0 7.06E+07 4.01E+07 - - - 2.8993 0.9452 221125_WJC_METTL3_EV_vs_WT_F05.05197.05197.2 1.36 12-Jun K.LQVQEQR.K "sp|Q9NQ34|TMM9B_HUMAN,sp|Q9P0T7|TMEM9_HUMAN,tr|B1ALM5|B1ALM5_HUMAN" 3 899.4825 1.82 59043 5197 2 899.480017 450.7485 Transmembrane protein 9B OS=Homo sapiens OX=9606 GN=TMEM9B PE=1 SV=1 6 1539.2 - 1.58E+06 - - - -2.7371 - 1.48 0.035 - 138.3 3 2 0 -0.0025 7 0 0 0 3.77E+07 2.07E+07 - - - 0.3278 0.9992 221125_WJC_METTL3_EV_vs_WT_F05.05203.05203.2 0.00378 18-Aug K.TDLGAAAGSK.R sp|Q9NX24|NHP2_HUMAN 1 889.4505 0.99 59047 5203 2 889.448644 445.7325 H\ACA ribonucleoprotein complex subunit 2 OS=Homo sapiens OX=9606 GN=NHP2 PE=1 SV=1 5.5 1539.8 - 1.88E+06 - - - -2.099 - 1.677 0.391 - 221.9 1 2 0 -0.0019 10 0 0 0 2.60E+08 2.64E+08 - - - 3.3715 0.9989 221125_WJC_METTL3_EV_vs_WT_F05.05204.05204.2 0.0155 16-Oct K.ALENDPDC[160.03]R[166.11].H "sp|P13797|PLST_HUMAN,sp|P13796|PLSL_HUMAN,tr|A0A0A0MSQ0|A0A0A0MSQ0_HUMAN,tr|Q5TBN3|Q5TBN3_HUMAN,tr|U3KQI3|U3KQI3_HUMAN" 5 1098.4639 0.65 59048 5204 2 1098.461445 550.2392 Plastin-3 OS=Homo sapiens OX=9606 GN=PLS3 PE=1 SV=4 4.03 1540 - 1.10E+06 - - - -2.2741 - 1.676 0.358 - 471.3 1 2 0 -0.0025 9 0 0 0 1.72E+07 2.65E+07 - - - 3.1784 0.9305 221125_WJC_METTL3_EV_vs_WT_F05.05207.05207.2 0.00594 12-Jul D.DDEEINK[136.11].M sp|Q6UB98|ANR12_HUMAN 1 869.3858 1.23 59050 5207 2 869.384572 435.7002 Ankyrin repeat domain-containing protein 12 OS=Homo sapiens OX=9606 GN=ANKRD12 PE=1 SV=3 3.92 1540.3 - 5.39E+06 - - - -1.4033 - 1.316 0.353 - 199.9 1 1 0 -0.0012 7 0 0 0 8.75E+07 7.10E+07 - - - 2.518 0.9448 221125_WJC_METTL3_EV_vs_WT_F05.05210.05210.2 0.000759 18-Oct Q.VATISANGDK.E "sp|P10809|CH60_HUMAN,tr|A0A7I2V599|A0A7I2V599_HUMAN,tr|E7EXB4|E7EXB4_HUMAN,tr|A0A7I2YQ71|A0A7I2YQ71_HUMAN,tr|E7ESH4|E7ESH4_HUMAN,tr|A0A7I2V5M1|A0A7I2V5M1_HUMAN,tr|A0A7I2V5K3|A0A7I2V5K3_HUMAN,tr|A0A7I2V369|A0A7I2V369_HUMAN" 8 974.5033 1.49 59052 5210 2 974.505051 488.2589 "60 kDa heat shock protein, mitochondrial OS=Homo sapiens OX=9606 GN=HSPD1 PE=1 SV=2" 5.81 1540.6 - 1.65E+06 - - - 1.8225 - 2.011 0.284 - 376.5 1 1 0 0.0018 10 0 0 0 1.74E+07 1.17E+07 - - - 3.0882 0.9995 221125_WJC_METTL3_EV_vs_WT_F05.05211.05211.2 0.00196 18-Oct K.TDLGAAAGSK[136.11].R sp|Q9NX24|NHP2_HUMAN 1 897.4647 0.96 59053 5211 2 897.462754 449.7396 H\ACA ribonucleoprotein complex subunit 2 OS=Homo sapiens OX=9606 GN=NHP2 PE=1 SV=1 5.5 1540.6 - 5.03E+06 - - - -2.1806 - 2.092 0.418 - 315.8 1 2 0 -0.002 10 0 0 0 2.60E+08 2.71E+08 - - - 4.1881 0.9831 221125_WJC_METTL3_EV_vs_WT_F05.05216.05216.2 0.000627 16-Sep L.VTSQIDAQR[166.11].R "sp|Q86V81|THOC4_HUMAN,tr|E9PB61|E9PB61_HUMAN" 2 1026.5333 0.5 59056 5216 2 1026.532727 514.2739 THO complex subunit 4 OS=Homo sapiens OX=9606 GN=ALYREF PE=1 SV=3 5.81 1541.2 - 2.91E+06 - - - -0.6001 - 1.931 0.371 - 464.5 1 1 0 -0.0006 9 0 0 0 3.57E+07 7.14E+07 - - - 3.6848 0.9843 221125_WJC_METTL3_EV_vs_WT_F05.05218.05218.2 0.00163 20-Dec P.GEVAGTVTGQK[136.11].R "sp|Q86U44|MTA70_HUMAN,tr|F5H6D8|F5H6D8_HUMAN,tr|H0YFV6|H0YFV6_HUMAN,tr|B4DTN4|B4DTN4_HUMAN" 4 1053.5546 0.02 59058 5218 2 1053.554402 527.7846 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 6 1541.4 - 6.83E+06 - - - -0.1765 - 2.449 0.304 - 567.9 1 1 0 -0.0002 11 0 0 0 3.35E+06 1.73E+08 - - - 3.7093 0.9958 221125_WJC_METTL3_EV_vs_WT_F05.05219.05219.2 0.865 14-Jul K.IQSGQC[160.03]LR[166.11].R sp|Q2TAY7|SMU1_HUMAN 1 970.4894 0.59 59059 5219 2 970.488813 486.252 WD40 repeat-containing protein SMU1 OS=Homo sapiens OX=9606 GN=SMU1 PE=1 SV=2 8.25 1541.4 - 1.91E+06 - - - -0.5739 - 1.364 0.191 - 163.6 2 2 0 -0.0006 8 0 0 0 1.70E+07 2.87E+07 - - - 1.2533 0.9975 221125_WJC_METTL3_EV_vs_WT_F05.05223.05223.2 0.19 20-Sep R.AGSQVVATTAR.H sp|Q9BWH2|FUND2_HUMAN 1 1059.5673 1.29 59061 5223 2 1059.566126 530.7909 FUN14 domain-containing protein 2 OS=Homo sapiens OX=9606 GN=FUNDC2 PE=1 SV=2 9.79 1541.9 - 611468 - - - -1.0816 - 1.497 0.222 - 219.6 1 2 0 -0.0011 11 0 0 0 2.09E+07 1.62E+07 - - - 1.7718 0.9817 221125_WJC_METTL3_EV_vs_WT_F05.05230.05230.2 0.171 22-Aug G.AAGVTDGNEVAK[136.11].A sp|Q9BX68|HINT2_HUMAN 1 1138.571 2.84 59066 5230 2 1138.570821 570.2928 Adenosine 5'-monophosphoramidase HINT2 OS=Homo sapiens OX=9606 GN=HINT2 PE=1 SV=1 4.37 1542.7 - 287942 - - - -0.1282 - 1.8 0.398 - 167.3 1 1 0 -0.0001 12 0 0 0 6.36E+06 2.24E+06 - - - 3.5271 0.9808 221125_WJC_METTL3_EV_vs_WT_F05.05231.05231.2 13.4 14-Jul K.KGGASKPR[166.11].T "sp|Q8NC96|NECP1_HUMAN,tr|A0A1W2PR09|A0A1W2PR09_HUMAN,tr|A0A1W2PRM0|A0A1W2PRM0_HUMAN,tr|F5GYH1|F5GYH1_HUMAN,tr|A0A1W2PRL5|A0A1W2PRL5_HUMAN,tr|A0A1W2PNT6|A0A1W2PNT6_HUMAN,tr|F5H2U7|F5H2U7_HUMAN,tr|A0A1W2PRW5|A0A1W2PRW5_HUMAN" 8 809.4747 - 59067 5231 2 809.474225 405.7446 Adaptin ear-binding coat-associated protein 1 OS=Homo sapiens OX=9606 GN=NECAP1 PE=1 SV=2 11.17 1542.7 - 3.68E+06 - - - -0.593 - 1.243 0.07 - 116.9 1 2 0 -0.0005 8 0 0 0 - - - - - 0.2139 0.9565 221125_WJC_METTL3_EV_vs_WT_F05.05235.05235.2 0.651 14-Jul K.IIAPPER[166.11]K[136.11].Y "sp|P63261|ACTG_HUMAN,sp|P68133|ACTS_HUMAN,sp|P62736|ACTA_HUMAN,sp|P68032|ACTC_HUMAN,sp|Q562R1|ACTBL_HUMAN,sp|P60709|ACTB_HUMAN,sp|P63267|ACTH_HUMAN,tr|A0A2R8YFE2|A0A2R8YFE2_HUMAN,tr|A0A804GS07|A0A804GS07_HUMAN,tr|A0A6Q8PFE4|A0A6Q8PFE4_HUMAN,tr|A0A804HKV3|A0A804HKV3_HUMAN,tr|I3L4N8|I3L4N8_HUMAN" 12 940.5825 0.99 59069 5235 2 940.582181 471.2985 "Actin, cytoplasmic 2 OS=Homo sapiens OX=9606 GN=ACTG1 PE=1 SV=1" 8.75 1543.3 - 6.42E+06 - - - -0.3094 - 1.178 0.016 - 186.9 1 2 0 -0.0003 8 0 0 0 6.16E+07 6.22E+07 - - - -0.3468 0.9998 221125_WJC_METTL3_EV_vs_WT_F05.05236.05236.2 0.0274 14-Sep K.QSQDEPLR.S "sp|Q13148|TADBP_HUMAN,tr|A0A087WX67|A0A087WX67_HUMAN,tr|G3V162|G3V162_HUMAN,tr|A0A087WV68|A0A087WV68_HUMAN,tr|A0A087WXV3|A0A087WXV3_HUMAN,tr|A0A087WYY0|A0A087WYY0_HUMAN,tr|K7EN94|K7EN94_HUMAN,tr|A0A0A0N0M3|A0A0A0N0M3_HUMAN,tr|A0A087WW61|A0A087WW61_HUMAN,tr|B1AKP7|B1AKP7_HUMAN,tr|K7EJM5|K7EJM5_HUMAN,tr|A0A087WZC9|A0A087WZC9_HUMAN,tr|A0A087WXQ5|A0A087WXQ5_HUMAN,tr|A0A087X260|A0A087X260_HUMAN" 14 971.4672 1.43 59070 5236 2 971.466189 486.7409 TAR DNA-binding protein 43 OS=Homo sapiens OX=9606 GN=TARDBP PE=1 SV=1 4.37 1543.3 - 5.56E+06 - - - -1.0644 - 2.064 0.455 - 462.5 1 2 0 -0.001 8 0 0 0 8.09E+08 5.67E+08 - - - 4.5868 0.9675 221125_WJC_METTL3_EV_vs_WT_F05.05237.05237.2 0.282 12-Jun R.TIEK[136.11]FEK[136.11].E "sp|Q05639|EF1A2_HUMAN,sp|P68104|EF1A1_HUMAN,sp|Q5VTE0|EF1A3_HUMAN,tr|A0A2R8Y488|A0A2R8Y488_HUMAN,tr|A0A2R8YDN5|A0A2R8YDN5_HUMAN,tr|A0A7I2V659|A0A7I2V659_HUMAN,tr|A0A7I2V3H3|A0A7I2V3H3_HUMAN,tr|Q5JR01|Q5JR01_HUMAN,tr|A0A2U3TZH3|A0A2U3TZH3_HUMAN,tr|A0A7I2V5N4|A0A7I2V5N4_HUMAN,tr|A0A087WVQ9|A0A087WVQ9_HUMAN,tr|A6PW80|A6PW80_HUMAN,tr|A0A087WV01|A0A087WV01_HUMAN,tr|A0A2R8Y660|A0A2R8Y660_HUMAN,tr|A0A6Q8PFK6|A0A6Q8PFK6_HUMAN" 15 909.5142 0.44 59071 5237 2 909.513943 455.7644 Elongation factor 1-alpha 2 OS=Homo sapiens OX=9606 GN=EEF1A2 PE=1 SV=1 5.81 1543.4 - 1.60E+07 - - - -0.32 - 1.293 0.22 - 118.4 1 2 1 -0.0003 7 0 0 0 7.66E+07 1.76E+08 - - - 1.48 0.9977 221125_WJC_METTL3_EV_vs_WT_F05.05238.05238.2 0.0205 12-Jul K.C[160.03]SESIPK.D "sp|P09874|PARP1_HUMAN,tr|A0A7I2V384|A0A7I2V384_HUMAN,tr|A0A7I2V5E9|A0A7I2V5E9_HUMAN,tr|A0A7I2V625|A0A7I2V625_HUMAN,tr|A0A7I2V3E1|A0A7I2V3E1_HUMAN" 5 819.3797 0.98 59072 5238 2 819.379662 410.6971 Poly [ADP-ribose] polymerase 1 OS=Homo sapiens OX=9606 GN=PARP1 PE=1 SV=4 5.99 1543.4 - 4.90E+06 - - - 0.0098 - 1.311 0.241 - 195.1 1 2 0 0 7 0 0 0 1.68E+08 1.71E+08 - - - 1.679 0.9998 221125_WJC_METTL3_EV_vs_WT_F05.05243.05243.2 0.00689 14-Aug K.QSQDEPLR[166.11].S "sp|Q13148|TADBP_HUMAN,tr|A0A087WX67|A0A087WX67_HUMAN,tr|G3V162|G3V162_HUMAN,tr|A0A087WV68|A0A087WV68_HUMAN,tr|A0A087WXV3|A0A087WXV3_HUMAN,tr|A0A087WYY0|A0A087WYY0_HUMAN,tr|K7EN94|K7EN94_HUMAN,tr|A0A0A0N0M3|A0A0A0N0M3_HUMAN,tr|A0A087WW61|A0A087WW61_HUMAN,tr|B1AKP7|B1AKP7_HUMAN,tr|K7EJM5|K7EJM5_HUMAN,tr|A0A087WZC9|A0A087WZC9_HUMAN,tr|A0A087WXQ5|A0A087WXQ5_HUMAN,tr|A0A087X260|A0A087X260_HUMAN" 14 981.4755 1.42 59075 5243 2 981.474841 491.745 TAR DNA-binding protein 43 OS=Homo sapiens OX=9606 GN=TARDBP PE=1 SV=1 4.37 1544 - 1.12E+07 - - - -0.6643 - 1.729 0.452 - 359.2 1 2 0 -0.0007 8 0 0 0 8.11E+08 5.70E+08 - - - 4.0306 0.9997 221125_WJC_METTL3_EV_vs_WT_F05.05244.05244.2 0.00107 12-Sep K.C[160.03]SESIPK[136.11].D "sp|P09874|PARP1_HUMAN,tr|A0A7I2V384|A0A7I2V384_HUMAN,tr|A0A7I2V5E9|A0A7I2V5E9_HUMAN,tr|A0A7I2V625|A0A7I2V625_HUMAN,tr|A0A7I2V3E1|A0A7I2V3E1_HUMAN" 5 827.3939 0.98 59076 5244 2 827.393523 414.7042 Poly [ADP-ribose] polymerase 1 OS=Homo sapiens OX=9606 GN=PARP1 PE=1 SV=4 5.99 1544.1 - 9.52E+06 - - - -0.4001 - 1.676 0.387 - 351.9 1 2 0 -0.0003 7 0 0 0 1.68E+08 1.71E+08 - - - 3.5356 0.7842 221125_WJC_METTL3_EV_vs_WT_F05.05246.05246.2 0.234 18-Jun D.EALGEESGER.W "sp|P56645|PER3_HUMAN,tr|Q8TAR6|Q8TAR6_HUMAN,tr|A0A087WV69|A0A087WV69_HUMAN" 3 1075.4782 999 59078 5246 2 1075.475863 538.7464 Period circadian protein homolog 3 OS=Homo sapiens OX=9606 GN=PER3 PE=1 SV=4 4.09 1544.2 - 4.40E+06 - - - -2.1563 - 1.311 0.276 - 106.4 1 1 0 -0.0023 10 0 0 0 5.17E+07 0.00E+00 - - - 1.8347 0.9953 221125_WJC_METTL3_EV_vs_WT_F05.05248.05248.2 0.301 14-Aug K.VPEPC[160.03]QPK.V "sp|P35321|SPR1A_HUMAN,sp|P22528|SPR1B_HUMAN" 2 953.4641 32.59 59080 5248 2 953.465559 477.7393 Cornifin-A OS=Homo sapiens OX=9606 GN=SPRR1A PE=1 SV=2 5.97 1544.2 - 2.65E+06 - - - 1.5806 - 1.382 0.212 - 241.8 1 2 0 0.0015 8 0 0 0 1.41E+09 4.32E+07 - - - 1.5821 0.9998 221125_WJC_METTL3_EV_vs_WT_F05.05249.05249.2 0.000174 16-Aug K.QC[160.03]PTENMAR.E sp|O43395|PRPF3_HUMAN 1 1105.4645 0.91 59081 5249 2 1105.463392 553.7395 U4\U6 small nuclear ribonucleoprotein Prp3 OS=Homo sapiens OX=9606 GN=PRPF3 PE=1 SV=2 5.99 1544.4 - 477263 - - - -0.9688 - 1.767 0.475 - 275.9 1 2 0 -0.0011 9 0 0 0 6.88E+06 7.55E+06 - - - 4.196 0.9886 221125_WJC_METTL3_EV_vs_WT_F05.05252.05252.2 0.334 14-Aug K.IIAPPERK.Y "sp|P63261|ACTG_HUMAN,sp|P68133|ACTS_HUMAN,sp|P62736|ACTA_HUMAN,sp|P68032|ACTC_HUMAN,sp|Q562R1|ACTBL_HUMAN,sp|P60709|ACTB_HUMAN,sp|P63267|ACTH_HUMAN,tr|A0A2R8YFE2|A0A2R8YFE2_HUMAN,tr|A0A804GS07|A0A804GS07_HUMAN,tr|A0A6Q8PFE4|A0A6Q8PFE4_HUMAN,tr|A0A804HKV3|A0A804HKV3_HUMAN,tr|I3L4N8|I3L4N8_HUMAN" 12 922.56 0.99 59082 5252 2 922.559533 462.2873 "Actin, cytoplasmic 2 OS=Homo sapiens OX=9606 GN=ACTG1 PE=1 SV=1" 8.75 1544.8 - 4.89E+06 - - - -0.5084 - 1.335 0.086 - 249 1 2 0 -0.0005 8 0 0 0 6.16E+07 6.22E+07 - - - 0.5475 0.912 221125_WJC_METTL3_EV_vs_WT_F05.05253.05253.2 0.112 18-Oct H.ISGATSVDQR.S sp|Q9NR30|DDX21_HUMAN 1 1032.52 0.93 59083 5253 2 1032.5231 517.2673 Nucleolar RNA helicase 2 OS=Homo sapiens OX=9606 GN=DDX21 PE=1 SV=5 5.84 1544.8 - 1.95E+06 - - - 3.015 - 2.132 0.306 - 273.3 1 1 0 0.0031 10 0 0 0 3.74E+07 4.01E+07 - - - 3.4133 0.9991 221125_WJC_METTL3_EV_vs_WT_F05.05254.05254.2 0.0199 14-Aug K.SEPVVSTR[166.11].K "sp|Q9NRY5|F1142_HUMAN,tr|E5RHI8|E5RHI8_HUMAN,tr|E5RHP2|E5RHP2_HUMAN,tr|E5RGF9|E5RGF9_HUMAN,tr|E5RFK2|E5RFK2_HUMAN,tr|E5RK42|E5RK42_HUMAN,tr|E5RH43|E5RH43_HUMAN" 7 883.4639 1.37 59084 5254 2 883.465745 442.7392 Protein FAM114A2 OS=Homo sapiens OX=9606 GN=FAM114A2 PE=1 SV=4 5.72 1544.9 - 3.16E+06 - - - 2.1269 - 1.713 0.363 - 344.6 1 2 0 0.0019 8 0 0 0 1.10E+08 7.98E+07 - - - 3.3449 0.9991 221125_WJC_METTL3_EV_vs_WT_F05.05255.05255.2 0.0095 12-Jul R.YSQIC[160.03]AK.V "sp|Q5VTU8|AT5EL_HUMAN,sp|P56381|ATP5E_HUMAN" 2 868.4113 1.38 59085 5255 2 868.411097 435.2129 "ATP synthase subunit epsilon-like protein, mitochondrial OS=Homo sapiens OX=9606 GN=ATP5F1EP2 PE=1 SV=1" 8.2 1544.9 - 1.85E+06 - - - -0.2211 - 1.33 0.336 - 111.7 1 2 0 -0.0002 7 0 0 0 2.48E+07 1.80E+07 - - - 2.4262 0.8749 221125_WJC_METTL3_EV_vs_WT_F05.05256.05256.2 5.49 12-Jun R.SQQSTPK[136.11].T sp|Q9NRL2|BAZ1A_HUMAN 1 782.4014 0.62 59086 5256 2 782.401562 392.208 Bromodomain adjacent to zinc finger domain protein 1A OS=Homo sapiens OX=9606 GN=BAZ1A PE=1 SV=2 8.47 1545 - 889797 - - - 0.2301 - 0.927 0.022 - 152.3 1 2 0 0.0002 7 0 0 0 2.13E+07 3.43E+07 - - - -1.0367 0.9999 221125_WJC_METTL3_EV_vs_WT_F05.05257.05257.2 1.69E-05 18-Oct K.FVQSEAQQER[166.11].C sp|O00311|CDC7_HUMAN 1 1230.5868 0.59 59087 5257 2 1230.588321 616.3007 Cell division cycle 7-related protein kinase OS=Homo sapiens OX=9606 GN=CDC7 PE=1 SV=1 4.53 1545.1 - 636056 - - - 1.2076 - 2.057 0.561 - 385.6 1 2 0 0.0015 10 0 0 0 3.47E+06 5.87E+06 - - - 5.1973 0.9997 221125_WJC_METTL3_EV_vs_WT_F05.05260.05260.2 5.54E-05 18-Aug K.FVQSEAQQER.C sp|O00311|CDC7_HUMAN 1 1220.5786 0.59 59090 5260 2 1220.580509 611.2966 Cell division cycle 7-related protein kinase OS=Homo sapiens OX=9606 GN=CDC7 PE=1 SV=1 4.53 1545.5 - 312953 - - - 1.5927 - 1.75 0.491 - 253.5 1 2 0 0.0019 10 0 0 0 3.47E+06 5.87E+06 - - - 4.229 0.9997 221125_WJC_METTL3_EV_vs_WT_F05.05263.05263.2 0.00132 18-Sep R.AQLEEASSAR.S sp|Q16352|AINX_HUMAN 1 1060.5149 2.84 59091 5263 2 1060.516021 531.2647 Alpha-internexin OS=Homo sapiens OX=9606 GN=INA PE=1 SV=2 4.53 1545.9 - 8.57E+06 - - - 1.0551 - 1.796 0.445 - 337.6 1 2 0 0.0011 10 0 0 0 1.52E+08 5.37E+07 - - - 3.9619 0.9998 221125_WJC_METTL3_EV_vs_WT_F05.05265.05265.2 0.000344 18-Oct R.AQLEEASSAR[166.11].S sp|Q16352|AINX_HUMAN 1 1070.5232 2.84 59093 5265 2 1070.523 536.2689 Alpha-internexin OS=Homo sapiens OX=9606 GN=INA PE=1 SV=2 4.53 1546 - 3.65E+06 - - - -0.1607 - 1.933 0.408 - 432 1 2 0 -0.0002 10 0 0 0 1.52E+08 5.37E+07 - - - 3.8941 0.9975 221125_WJC_METTL3_EV_vs_WT_F05.05266.05266.2 0.0266 14-Aug K.IQNEQLEK.L sp|P12270|TPR_HUMAN 1 1000.5189 3.19 59094 5266 2 1000.518099 501.2667 Nucleoprotein TPR OS=Homo sapiens OX=9606 GN=TPR PE=1 SV=3 4.53 1546.1 - 3.00E+06 - - - -0.8256 - 1.701 0.162 - 154.1 2 2 0 -0.0008 8 0 0 0 1.88E+08 5.89E+07 - - - 1.7049 0.9993 221125_WJC_METTL3_EV_vs_WT_F05.05271.05271.2 0.104 16-Dec K.QLANQTVGR[166.11].A "sp|Q68EM7|RHG17_HUMAN,sp|Q17R89|RHG44_HUMAN,tr|I3L1S9|I3L1S9_HUMAN,tr|I3L4P0|I3L4P0_HUMAN,tr|J3KRS3|J3KRS3_HUMAN,tr|F5H6L3|F5H6L3_HUMAN,tr|E7ERK8|E7ERK8_HUMAN" 7 995.5388 1.4 59099 5271 2 995.538813 498.7767 Rho GTPase-activating protein 17 OS=Homo sapiens OX=9606 GN=ARHGAP17 PE=1 SV=1 9.75 1546.4 - 1.32E+06 - - - 0.0512 - 2.073 0.212 - 961.5 1 2 0 0.0001 9 0 0 0 1.12E+08 8.01E+07 - - - 2.7158 0.9997 221125_WJC_METTL3_EV_vs_WT_F05.05274.05274.2 2.22E-05 20-Oct K.LLAQQHPPPDR.Q "sp|Q9Y520|PRC2C_HUMAN,tr|A0A0A0MS30|A0A0A0MS30_HUMAN,tr|E7EPN9|E7EPN9_HUMAN" 3 1270.6782 1.63 59102 5274 2 1270.679434 636.3464 Protein PRRC2C OS=Homo sapiens OX=9606 GN=PRRC2C PE=1 SV=4 6.74 1546.7 - 204518 - - - 0.9562 - 1.736 0.473 - 187.8 1 2 0 0.0012 11 0 0 0 4.43E+06 2.73E+06 - - - 4.0264 0.9979 221125_WJC_METTL3_EV_vs_WT_F05.05281.05281.3 0.00744 Sep-40 K.LLAQQHPPPDR[166.11].Q "sp|Q9Y520|PRC2C_HUMAN,tr|A0A0A0MS30|A0A0A0MS30_HUMAN,tr|E7EPN9|E7EPN9_HUMAN" 3 1280.6865 1.41 59107 5281 3 1280.686351 427.9028 Protein PRRC2C OS=Homo sapiens OX=9606 GN=PRRC2C PE=1 SV=4 6.74 1547.3 - 3.14E+06 - - - -0.1078 - 1.791 0.233 - 108.9 1 2 0 -0.0001 11 0 0 0 1.55E+08 1.10E+08 - - - 2.7932 0.9974 221125_WJC_METTL3_EV_vs_WT_F05.05283.05283.3 3.07E-05 13/44 R.FPATGAHPAAAR.P sp|P31274|HXC9_HUMAN 1 1165.5992 2.01 59109 5283 3 1165.598969 389.5404 Homeobox protein Hox-C9 OS=Homo sapiens OX=9606 GN=HOXC9 PE=1 SV=3 9.76 1547.4 - 1.88E+06 - - - -0.2334 - 2.661 0.492 - 182.3 1 1 0 -0.0003 12 0 0 0 4.94E+07 2.46E+07 - - - 6.7381 0.9991 221125_WJC_METTL3_EV_vs_WT_F05.05290.05290.2 0.0168 14-Sep K.IQNEQLEK[136.11].L sp|P12270|TPR_HUMAN 1 1008.5331 3.18 59114 5290 2 1008.532968 505.2738 Nucleoprotein TPR OS=Homo sapiens OX=9606 GN=TPR PE=1 SV=3 4.53 1548.3 - 5.18E+06 - - - -0.1557 - 1.971 0.205 - 199.9 2 2 0 -0.0002 8 0 0 0 1.88E+08 5.89E+07 - - - 2.4671 0.9889 221125_WJC_METTL3_EV_vs_WT_F05.05292.05292.3 0.00231 15/44 R.FPATGAHPAAAR[166.11].P sp|P31274|HXC9_HUMAN 1 1175.6075 2.68 59116 5292 3 1175.60746 392.8764 Homeobox protein Hox-C9 OS=Homo sapiens OX=9606 GN=HOXC9 PE=1 SV=3 9.76 1548.4 - 1.27E+06 - - - -0.0434 - 2.542 0.359 - 261.1 1 1 0 -0.0001 12 0 0 0 7.87E+07 2.94E+07 - - - 5.1285 0.9998 221125_WJC_METTL3_EV_vs_WT_F05.05293.05293.2 0.00386 20-Oct R.LASC[160.03]SADGTVR.L "sp|Q9NRL3|STRN4_HUMAN,tr|F5GYK2|F5GYK2_HUMAN,tr|M0QZM0|M0QZM0_HUMAN,tr|M0R317|M0R317_HUMAN" 4 1135.5292 2.62 59117 5293 2 1135.529784 568.7719 Striatin-4 OS=Homo sapiens OX=9606 GN=STRN4 PE=1 SV=2 5.83 1548.5 - 659483 - - - 0.539 - 2.285 0.409 - 423.1 1 2 0 0.0006 11 0 0 0 1.34E+07 5.13E+06 - - - 4.2972 0.9981 221125_WJC_METTL3_EV_vs_WT_F05.05296.05296.2 0.321 12-Jun R.KLLDEGR.S "sp|Q8IWZ3|ANKH1_HUMAN,tr|E9PDP5|E9PDP5_HUMAN,tr|D6RHC4|D6RHC4_HUMAN" 3 829.4658 1.85 59118 5296 2 829.465355 415.7402 Ankyrin repeat and KH domain-containing protein 1 OS=Homo sapiens OX=9606 GN=ANKHD1 PE=1 SV=1 6.07 1548.9 - 3.74E+06 - - - -0.4967 - 1.412 0.233 - 176.9 1 2 0 -0.0004 7 0 0 0 4.84E+07 2.62E+07 - - - 1.855 0.9997 221125_WJC_METTL3_EV_vs_WT_F05.05298.05298.2 0.00238 16-Nov K.QLANQTVGR.A "sp|Q68EM7|RHG17_HUMAN,sp|Q17R89|RHG44_HUMAN,tr|I3L1S9|I3L1S9_HUMAN,tr|I3L4P0|I3L4P0_HUMAN,tr|J3KRS3|J3KRS3_HUMAN,tr|F5H6L3|F5H6L3_HUMAN,tr|E7ERK8|E7ERK8_HUMAN" 7 985.5305 1.37 59119 5298 2 985.531101 493.7725 Rho GTPase-activating protein 17 OS=Homo sapiens OX=9606 GN=ARHGAP17 PE=1 SV=1 9.75 1549.1 - 9.39E+06 - - - 0.6179 - 2.229 0.339 - 675.3 1 2 0 0.0006 9 0 0 0 1.12E+08 8.13E+07 - - - 3.8636 0.9923 221125_WJC_METTL3_EV_vs_WT_F05.05299.05299.2 0.111 12-Jun K.HTPLYER[166.11].S "sp|Q5T035|CI129_HUMAN,sp|Q9NZB2|F120A_HUMAN,tr|A0A0C4DH52|A0A0C4DH52_HUMAN" 3 924.4693 0.87 59120 5299 2 924.470458 463.2419 Putative uncharacterized protein C9orf129 OS=Homo sapiens OX=9606 GN=C9orf129 PE=4 SV=1 6.75 1549.2 - 1.53E+06 - - - 1.2678 - 1.068 0.249 - 120.5 1 2 0 0.0012 7 0 0 0 2.22E+07 2.55E+07 - - - 1.0882 0.9996 221125_WJC_METTL3_EV_vs_WT_F05.05307.05307.2 0.0084 14-Jul K.SEPVVSTR.K "sp|Q9NRY5|F1142_HUMAN,tr|E5RHI8|E5RHI8_HUMAN,tr|E5RHP2|E5RHP2_HUMAN,tr|E5RGF9|E5RGF9_HUMAN,tr|E5RFK2|E5RFK2_HUMAN,tr|E5RK42|E5RK42_HUMAN,tr|E5RH43|E5RH43_HUMAN" 7 873.4556 0.93 59125 5307 2 873.45547 437.7351 Protein FAM114A2 OS=Homo sapiens OX=9606 GN=FAM114A2 PE=1 SV=4 5.72 1550.1 - 4.16E+06 - - - -0.1443 - 1.45 0.41 - 283 1 2 0 -0.0001 8 0 0 0 1.18E+08 1.27E+08 - - - 3.1898 0.9693 221125_WJC_METTL3_EV_vs_WT_F05.05308.05308.2 0.0233 14-Sep T.LQGHSVIR.S "sp|Q8WXI9|P66B_HUMAN,tr|A0A0U1RRM1|A0A0U1RRM1_HUMAN" 2 908.5192 2.15 59126 5308 2 908.519086 455.2669 Transcriptional repressor p66-beta OS=Homo sapiens OX=9606 GN=GATAD2B PE=1 SV=1 9.76 1550.2 - 1.19E+06 - - - -0.1244 - 1.866 0.276 - 288.2 1 1 0 -0.0001 8 0 0 0 3.15E+07 1.47E+07 - - - 2.9608 0.9989 221125_WJC_METTL3_EV_vs_WT_F05.05313.05313.2 0.000713 16-Sep R.TLQGHSVIR.S "sp|Q8WXI9|P66B_HUMAN,tr|A0A0U1RRM1|A0A0U1RRM1_HUMAN" 2 1009.5669 1.51 59129 5313 2 1009.568575 505.7907 Transcriptional repressor p66-beta OS=Homo sapiens OX=9606 GN=GATAD2B PE=1 SV=1 9.44 1550.8 - 7.73E+06 - - - 1.6809 - 1.496 0.367 - 285.9 1 2 0 0.0017 9 0 0 0 8.28E+07 5.50E+07 - - - 2.9164 0.8646 221125_WJC_METTL3_EV_vs_WT_F05.05314.05314.2 0.03 12-Sep L.QGHSVIR.S "sp|Q8WXI9|P66B_HUMAN,tr|A0A0U1RRM1|A0A0U1RRM1_HUMAN" 2 795.4351 1.56 59130 5314 2 795.435585 398.7248 Transcriptional repressor p66-beta OS=Homo sapiens OX=9606 GN=GATAD2B PE=1 SV=1 9.76 1550.9 - 4.81E+06 - - - 0.5657 - 1.313 0.239 - 427.1 1 1 0 0.0004 7 0 0 0 4.45E+07 2.84E+07 - - - 1.669 0.8378 221125_WJC_METTL3_EV_vs_WT_F05.05315.05315.2 0.0639 12-Jul L.QGHSVIR[166.11].S "sp|Q8WXI9|P66B_HUMAN,tr|A0A0U1RRM1|A0A0U1RRM1_HUMAN" 2 805.4434 1.59 59131 5315 2 805.443807 403.729 Transcriptional repressor p66-beta OS=Homo sapiens OX=9606 GN=GATAD2B PE=1 SV=1 9.76 1550.9 - 2.62E+06 - - - 0.4991 - 1.247 0.237 - 238.7 1 1 0 0.0004 7 0 0 0 4.47E+07 2.81E+07 - - - 1.4908 0.9605 221125_WJC_METTL3_EV_vs_WT_F05.05316.05316.2 0.00708 14-Sep T.LQGHSVIR[166.11].S "sp|Q8WXI9|P66B_HUMAN,tr|A0A0U1RRM1|A0A0U1RRM1_HUMAN" 2 918.5275 2.29 59132 5316 2 918.528204 460.271 Transcriptional repressor p66-beta OS=Homo sapiens OX=9606 GN=GATAD2B PE=1 SV=1 9.76 1551 - 1.47E+06 - - - 0.8002 - 1.817 0.279 - 295.1 1 1 0 0.0007 8 0 0 0 3.80E+07 1.66E+07 - - - 2.9026 0.9921 221125_WJC_METTL3_EV_vs_WT_F05.05317.05317.2 0.246 12-Jun R.EESSIPR.A sp|P53701|CCHL_HUMAN 1 816.3977 2.42 59133 5317 2 816.396609 409.2061 Holocytochrome c-type synthase OS=Homo sapiens OX=9606 GN=HCCS PE=1 SV=1 4.53 1551.1 - 1.35E+06 - - - -1.3939 - 1.29 0.162 - 199.7 1 2 0 -0.0011 7 0 0 0 4.45E+07 1.84E+07 - - - 1.044 0.9994 221125_WJC_METTL3_EV_vs_WT_F05.05319.05319.2 0.0117 14-Aug K.DNDSLAAR.L sp|P54886|P5CS_HUMAN 1 860.3988 1.61 59135 5319 2 860.397402 431.2067 Delta-1-pyrroline-5-carboxylate synthase OS=Homo sapiens OX=9606 GN=ALDH18A1 PE=1 SV=2 4.21 1551.2 - 1.26E+06 - - - -1.6353 - 1.76 0.361 - 304.5 1 2 0 -0.0014 8 0 0 0 4.25E+07 2.64E+07 - - - 3.4119 0.9997 221125_WJC_METTL3_EV_vs_WT_F05.05320.05320.2 0.00799 18-Nov R.SPVSSQQSLK[136.11].N sp|Q8IWJ2|GCC2_HUMAN 1 1067.5702 6.95 59136 5320 2 1067.569357 534.7924 GRIP and coiled-coil domain-containing protein 2 OS=Homo sapiens OX=9606 GN=GCC2 PE=1 SV=4 8.47 1551.3 - 889193 - - - -0.8252 - 2.149 0.32 - 388.2 1 2 0 -0.0009 10 0 0 0 9.38E+07 1.35E+07 - - - 3.5396 0.9979 221125_WJC_METTL3_EV_vs_WT_F05.05321.05321.2 0.304 16-Sep K.RAFDSAVAK.A "sp|Q16891|MIC60_HUMAN,tr|B9A067|B9A067_HUMAN,tr|C9J406|C9J406_HUMAN,tr|H7C463|H7C463_HUMAN" 4 963.5138 1.48 59137 5321 2 963.514002 482.7642 MICOS complex subunit MIC60 OS=Homo sapiens OX=9606 GN=IMMT PE=1 SV=1 8.75 1551.3 - 768328 - - - 0.2304 - 1.643 0.175 - 198.5 1 2 0 0.0002 9 0 0 0 8.70E+06 5.86E+06 - - - 1.77 0.9934 221125_WJC_METTL3_EV_vs_WT_F05.05327.05327.2 0.893 16-Jul R.SAVPPGADK.K "sp|P46783|RS10_HUMAN,tr|F6U211|F6U211_HUMAN,tr|A0A1W2PQS6|A0A1W2PQS6_HUMAN,tr|A0A2R8YFH6|A0A2R8YFH6_HUMAN,tr|A0A2R8Y7H1|A0A2R8Y7H1_HUMAN,tr|S4R435|S4R435_HUMAN" 6 840.4341 1.17 59141 5327 2 840.432793 421.2243 40S ribosomal protein S10 OS=Homo sapiens OX=9606 GN=RPS10 PE=1 SV=1 5.55 1552.1 - 5.42E+06 - - - -1.5932 - 1.206 0.227 - 164.2 1 2 0 -0.0013 9 0 0 0 9.63E+07 8.20E+07 - - - 1.2591 0.9911 221125_WJC_METTL3_EV_vs_WT_F05.05329.05329.2 0.911 12-Jun R.QLSALHR[166.11].A "sp|P61313|RL15_HUMAN,tr|A0A2R8YEM3|A0A2R8YEM3_HUMAN,tr|A0A2R8Y738|A0A2R8Y738_HUMAN,tr|E7EQV9|E7EQV9_HUMAN,tr|E7EX53|E7EX53_HUMAN,tr|E7ENU7|E7ENU7_HUMAN" 6 833.4747 0.19 59143 5329 2 833.474741 417.7446 60S ribosomal protein L15 OS=Homo sapiens OX=9606 GN=RPL15 PE=1 SV=2 9.76 1552.2 - 2.54E+06 - - - 0.0432 - 1.325 0.122 - 218.8 2 2 0 0 7 0 0 0 9.99E+06 5.17E+07 - - - 0.6993 0.9953 221125_WJC_METTL3_EV_vs_WT_F05.05330.05330.2 0.153 12-Jun R.EESSIPR[166.11].A sp|P53701|CCHL_HUMAN 1 826.406 2.46 59144 5330 2 826.405185 414.2103 Holocytochrome c-type synthase OS=Homo sapiens OX=9606 GN=HCCS PE=1 SV=1 4.53 1552.3 - 1.91E+06 - - - -1.0068 - 1.303 0.19 - 232.4 1 2 0 -0.0008 7 0 0 0 4.35E+07 1.77E+07 - - - 1.2827 0.9852 221125_WJC_METTL3_EV_vs_WT_F05.05336.05336.2 0.179 18-Aug K.EAGAVVPQSK[136.11].Y sp|Q9HDC5|JPH1_HUMAN 1 992.5382 4.07 59150 5336 2 992.536756 497.2764 Junctophilin-1 OS=Homo sapiens OX=9606 GN=JPH1 PE=1 SV=2 6.1 1552.6 - 811052 - - - -1.4649 - 1.34 0.105 - 172.9 1 2 0 -0.0015 10 0 0 0 5.26E+07 1.29E+07 - - - 0.633 1 221125_WJC_METTL3_EV_vs_WT_F05.05337.05337.2 8.31E-06 20-Dec R.MVTETEETQEK.K sp|Q6IQ49|SDE2_HUMAN 1 1323.5864 1.5 59151 5337 2 1323.584043 662.8005 Replication stress response regulator SDE2 OS=Homo sapiens OX=9606 GN=SDE2 PE=1 SV=1 4.09 1552.7 - 314622 - - - -1.7898 - 2.439 0.586 - 386.2 1 2 0 -0.0024 11 0 0 0 1.62E+07 1.08E+07 - - - 5.7804 0.9767 221125_WJC_METTL3_EV_vs_WT_F05.05343.05343.2 0.92 18-Jun R.AQLGGPEAAK.S "sp|P04792|HSPB1_HUMAN,tr|A0A6Q8PFK8|A0A6Q8PFK8_HUMAN,tr|C9J3N8|C9J3N8_HUMAN,tr|A0A6Q8PGK1|A0A6Q8PGK1_HUMAN" 4 940.4978 0.21 59155 5343 2 940.498773 471.2562 Heat shock protein beta-1 OS=Homo sapiens OX=9606 GN=HSPB1 PE=1 SV=2 6.05 1553.4 - 2.39E+06 - - - 1.0399 - 1.171 0.151 - 108.4 6 2 0 0.001 10 0 0 0 8.59E+07 4.09E+08 - - - 0.249 0.9997 221125_WJC_METTL3_EV_vs_WT_F05.05344.05344.2 0.000148 18-Aug K.GEVVEGDPDK[136.11].V "sp|O43615|TIM44_HUMAN,tr|M0QXM9|M0QXM9_HUMAN" 2 1051.4913 1.36 59156 5344 2 1051.489356 526.7529 Mitochondrial import inner membrane translocase subunit TIM44 OS=Homo sapiens OX=9606 GN=TIMM44 PE=1 SV=2 3.92 1553.5 - 3.26E+06 - - - -1.8669 - 1.802 0.525 - 297.7 1 2 0 -0.002 10 0 0 0 1.02E+08 7.49E+07 - - - 4.5618 1 221125_WJC_METTL3_EV_vs_WT_F05.05348.05348.2 1.89E-07 20-Dec R.MVTETEETQEK[136.11].K sp|Q6IQ49|SDE2_HUMAN 1 1331.6006 1.5 59160 5348 2 1331.601379 666.8076 Replication stress response regulator SDE2 OS=Homo sapiens OX=9606 GN=SDE2 PE=1 SV=1 4.09 1554 - 669881 - - - 0.576 - 2.502 0.607 - 356.8 1 2 0 0.0008 11 0 0 0 1.62E+07 1.08E+07 - - - 6.005 0.9986 221125_WJC_METTL3_EV_vs_WT_F05.05354.05354.2 0.0599 14-Jul R.EITSLHER.N sp|P12270|TPR_HUMAN 1 983.5036 3.33 59164 5354 2 983.502844 492.7591 Nucleoprotein TPR OS=Homo sapiens OX=9606 GN=TPR PE=1 SV=3 5.4 1554.6 - 2.73E+06 - - - -0.7778 - 1.562 0.243 - 207.7 1 2 0 -0.0008 8 0 0 0 2.98E+07 8.93E+06 - - - 2.1806 0.986 221125_WJC_METTL3_EV_vs_WT_F05.05355.05355.2 0.00159 16-Sep R.ASEASQGFR[166.11].F "sp|Q9H992|MARH7_HUMAN,tr|F5H6W4|F5H6W4_HUMAN" 2 961.4493 1.08 59165 5355 2 961.446512 481.7319 E3 ubiquitin-protein ligase MARCHF7 OS=Homo sapiens OX=9606 GN=MARCHF7 PE=1 SV=1 6.05 1554.8 - 1.39E+06 - - - -2.8779 - 1.597 0.132 - 282.9 1 2 0 -0.0028 9 0 0 0 1.91E+07 1.77E+07 - - - 1.3694 0.9373 221125_WJC_METTL3_EV_vs_WT_F05.05358.05358.2 0.271 18-Oct F.HLGGPAVGPR.G "sp|P43243|MATR3_HUMAN,tr|D6RE02|D6RE02_HUMAN,tr|B3KM87|B3KM87_HUMAN,tr|A8MXP9|A8MXP9_HUMAN,tr|D6RAY2|D6RAY2_HUMAN,tr|D6R991|D6R991_HUMAN,tr|A0A0R4J2E8|A0A0R4J2E8_HUMAN,tr|D6RAM9|D6RAM9_HUMAN,tr|D6RIA2|D6RIA2_HUMAN,tr|H0Y8T4|H0Y8T4_HUMAN,tr|D6REM6|D6REM6_HUMAN,tr|D6RBI2|D6RBI2_HUMAN" 12 959.5301 0.25 59166 5358 2 959.529254 480.7723 Matrin-3 OS=Homo sapiens OX=9606 GN=MATR3 PE=1 SV=2 9.76 1555.1 - 1.72E+06 - - - -0.8796 - 1.547 0.289 - 261.4 1 1 0 -0.0008 10 0 0 0 4.08E+07 1.66E+08 - - - 2.3932 0.8873 221125_WJC_METTL3_EV_vs_WT_F05.05361.05361.2 2.06 12-Sep A.R[166.11]IEDLER[166.11].A "sp|Q92817|EVPL_HUMAN,tr|K7EKI0|K7EKI0_HUMAN" 2 949.5096 0.96 59167 5361 2 949.508572 475.7621 Envoplakin OS=Homo sapiens OX=9606 GN=EVPL PE=1 SV=3 4.68 1555.5 - 6.29E+07 - - - -1.0658 - 1.991 0.094 - 315.4 1 1 0 -0.001 7 0 0 0 7.14E+08 7.43E+08 - - - 1.917 0.9977 221125_WJC_METTL3_EV_vs_WT_F05.05367.05367.2 0.00223 20-Nov R.SLATGQPATSR.L "sp|Q9ULL5|PRR12_HUMAN,tr|A0A3Q5ADB5|A0A3Q5ADB5_HUMAN" 2 1087.5622 3.45 59171 5367 2 1087.565244 544.7884 Proline-rich protein 12 OS=Homo sapiens OX=9606 GN=PRR12 PE=1 SV=3 9.47 1556.2 - 1.37E+06 - - - 2.8118 - 1.667 0.331 - 280.7 1 2 0 0.0031 11 0 0 0 1.15E+07 3.34E+06 - - - 2.8673 0.8986 221125_WJC_METTL3_EV_vs_WT_F05.05373.05373.2 7.1 12-Jun K.TQIPTQR.Y "sp|P25786|PSA1_HUMAN,tr|F5GX11|F5GX11_HUMAN" 2 842.461 0.81 59175 5373 2 842.461603 422.2378 Proteasome subunit alpha type-1 OS=Homo sapiens OX=9606 GN=PSMA1 PE=1 SV=1 9.41 1556.7 - 3.12E+06 - - - 0.6968 - 1.016 0.013 - 194.4 1 2 0 0.0006 7 0 0 0 1.03E+08 1.27E+08 - - - -0.8129 0.9997 221125_WJC_METTL3_EV_vs_WT_F05.05374.05374.2 0.00124 14-Aug R.TASFSESR[166.11].A sp|P53396|ACLY_HUMAN 1 893.4118 0.89 59176 5374 2 893.411456 447.7132 ATP-citrate synthase OS=Homo sapiens OX=9606 GN=ACLY PE=1 SV=3 5.66 1556.8 - 2.84E+06 - - - -0.4186 - 1.581 0.451 - 255.4 1 2 0 -0.0004 8 0 0 0 2.88E+07 3.25E+07 - - - 3.7534 0.9859 221125_WJC_METTL3_EV_vs_WT_F05.05379.05379.2 0.000134 22-Aug N.VLQGGEGQAPTR.Q "sp|P24752|THIL_HUMAN,tr|A0A5F9ZHL7|A0A5F9ZHL7_HUMAN,tr|A0A5F9ZHJ7|A0A5F9ZHJ7_HUMAN,tr|A0A5F9ZHH9|A0A5F9ZHH9_HUMAN,tr|A0A5F9ZHJ0|A0A5F9ZHJ0_HUMAN,tr|A0A5F9ZHL1|A0A5F9ZHL1_HUMAN,tr|E9PRQ6|E9PRQ6_HUMAN,tr|H0YEL7|H0YEL7_HUMAN" 8 1211.6258 1.59 59181 5379 2 1211.626927 606.8202 "Acetyl-CoA acetyltransferase, mitochondrial OS=Homo sapiens OX=9606 GN=ACAT1 PE=1 SV=1" 5.97 1557.3 - 392828 - - - 0.8897 - 1.725 0.498 - 168.3 1 1 0 0.0011 12 0 0 0 5.34E+06 3.36E+06 - - - 4.1535 0.9998 221125_WJC_METTL3_EV_vs_WT_F05.05382.05382.2 0.000777 14-Sep K.TSEVNC[160.03]YR[166.11].C sp|P62633|CNBP_HUMAN 1 1037.4476 0.64 59182 5382 2 1037.448175 519.7311 CCHC-type zinc finger nucleic acid binding protein OS=Homo sapiens OX=9606 GN=CNBP PE=1 SV=1 5.66 1557.7 - 1.13E+07 - - - 0.5889 - 1.737 0.454 - 500.1 1 2 0 0.0006 8 0 0 0 1.16E+08 1.80E+08 - - - 4.0593 0.9995 221125_WJC_METTL3_EV_vs_WT_F05.05383.05383.2 0.00205 12-Aug K.SC[160.03]GYSVR[166.11].F sp|Q08211|DHX9_HUMAN 1 837.3679 0.52 59183 5383 2 837.367063 419.6912 ATP-dependent RNA helicase A OS=Homo sapiens OX=9606 GN=DHX9 PE=1 SV=4 7.94 1557.7 - 8.32E+06 - - - -0.9482 - 1.445 0.407 - 297 1 2 0 -0.0008 7 0 0 0 7.86E+07 1.51E+08 - - - 3.2132 0.9991 221125_WJC_METTL3_EV_vs_WT_F05.05384.05384.2 0.0103 12-Jul K.TEQFQAR.K sp|Q9H501|ESF1_HUMAN 1 878.4246 0.22 59184 5384 2 878.423995 440.2196 ESF1 homolog OS=Homo sapiens OX=9606 GN=ESF1 PE=1 SV=1 5.66 1557.8 - 2.84E+06 - - - -0.7229 - 1.299 0.356 - 313 1 2 0 -0.0006 7 0 0 0 3.20E+07 1.44E+08 - - - 2.4991 0.9909 221125_WJC_METTL3_EV_vs_WT_F05.05385.05385.2 0.658 12-Jun K.MQASIEK.G "sp|P06748|NPM_HUMAN,tr|E5RI98|E5RI98_HUMAN,tr|A0A7I2YQC0|A0A7I2YQC0_HUMAN,tr|A0A7I2V5J8|A0A7I2V5J8_HUMAN,tr|A0A7I2V5S2|A0A7I2V5S2_HUMAN" 5 805.4004 0.83 59185 5385 2 805.400048 403.7075 Nucleophosmin OS=Homo sapiens OX=9606 GN=NPM1 PE=1 SV=2 5.75 1557.9 - 2.43E+06 - - - -0.4234 - 1.303 0.11 - 138.9 1 2 0 -0.0003 7 0 0 0 2.47E+07 2.99E+07 - - - 0.692 0.9973 221125_WJC_METTL3_EV_vs_WT_F05.05386.05386.2 0.000774 16-Sep R.SAEAELQSK.R sp|Q15149|PLEC_HUMAN 1 961.4716 1.9 59186 5386 2 961.475386 481.7431 Plectin OS=Homo sapiens OX=9606 GN=PLEC PE=1 SV=3 4.53 1557.9 - 2.36E+06 - - - 3.8961 - 1.656 0.413 - 306.3 1 2 0 0.0037 9 0 0 0 4.11E+07 2.17E+07 - - - 3.5495 0.88 221125_WJC_METTL3_EV_vs_WT_F05.05388.05388.2 0.00957 12-Jun L.AFGGHQR.H "sp|Q14683|SMC1A_HUMAN,tr|G8JLG1|G8JLG1_HUMAN,tr|A0A6Q8PHC3|A0A6Q8PHC3_HUMAN" 3 771.3776 1 59188 5388 2 771.378515 386.6961 Structural maintenance of chromosomes protein 1A OS=Homo sapiens OX=9606 GN=SMC1A PE=1 SV=2 9.8 1558.1 - 1.33E+06 - - - 1.1603 - 1.265 0.297 - 140.6 1 1 0 0.0009 7 0 0 0 2.41E+07 2.41E+07 - - - 1.9792 0.9883 221125_WJC_METTL3_EV_vs_WT_F05.05391.05391.2 0.192 18-Jun R.DAVTYTEHAK.R sp|P62805|H4_HUMAN 1 1133.5353 4.16 59191 5391 2 1133.534204 567.7749 Histone H4 OS=Homo sapiens OX=9606 GN=H4C1 PE=1 SV=2 5.32 1558.4 - 214094 - - - -0.9695 - 1.186 0.15 - 67.8 1 2 0 -0.0011 10 0 0 0 7.01E+07 1.69E+07 - - - 0.6247 0.9988 221125_WJC_METTL3_EV_vs_WT_F05.05395.05395.2 0.0187 16-Aug K.GEPGPNDVR.G "sp|Q6PKG0|LARP1_HUMAN,tr|A0A0B4J210|A0A0B4J210_HUMAN" 2 939.441 1.41 59193 5395 2 939.442167 470.7278 La-related protein 1 OS=Homo sapiens OX=9606 GN=LARP1 PE=1 SV=2 4.37 1558.9 - 3.70E+06 - - - 1.2326 - 1.519 0.313 - 278.1 1 2 0 0.0012 9 0 0 0 8.16E+07 5.80E+07 - - - 2.5619 0.9991 221125_WJC_METTL3_EV_vs_WT_F05.05396.05396.2 0.0434 12-Aug K.QGEDFSR[166.11].T "sp|O00461|GOLI4_HUMAN,tr|F8W785|F8W785_HUMAN" 2 847.37 3.26 59194 5396 2 847.369715 424.6923 Golgi integral membrane protein 4 OS=Homo sapiens OX=9606 GN=GOLIM4 PE=1 SV=1 4.37 1558.9 - 3.95E+06 - - - -0.2962 - 1.52 0.281 - 326.9 1 2 0 -0.0003 7 0 0 0 1.51E+08 4.63E+07 - - - 2.4431 0.9976 221125_WJC_METTL3_EV_vs_WT_F05.05399.05399.2 0.0181 16-Jun K.EGIPPDQQR[166.11].L "sp|P62979|RS27A_HUMAN,sp|P0CG48|UBC_HUMAN,sp|P0CG48|UBC_HUMAN,sp|P0CG48|UBC_HUMAN,sp|P0CG48|UBC_HUMAN,sp|P0CG48|UBC_HUMAN,sp|P0CG48|UBC_HUMAN,sp|P0CG48|UBC_HUMAN,sp|P0CG48|UBC_HUMAN,sp|P0CG48|UBC_HUMAN,sp|P0CG47|UBB_HUMAN,sp|P0CG47|UBB_HUMAN,sp|P0CG47|UBB_HUMAN,sp|P62987|RL40_HUMAN,tr|F5H388|F5H388_HUMAN,tr|F5H388|F5H388_HUMAN,tr|F5GYU3|F5GYU3_HUMAN,tr|F5GYU3|F5GYU3_HUMAN,tr|B4DV12|B4DV12_HUMAN,tr|B4DV12|B4DV12_HUMAN,tr|J3QSA3|J3QSA3_HUMAN,tr|Q5PY61|Q5PY61_HUMAN,tr|Q5PY61|Q5PY61_HUMAN,tr|Q5PY61|Q5PY61_HUMAN,tr|F5H2Z3|F5H2Z3_HUMAN,tr|F5H2Z3|F5H2Z3_HUMAN,tr|M0R2S1|M0R2S1_HUMAN,tr|J3QS39|J3QS39_HUMAN,tr|J3QTR3|J3QTR3_HUMAN,tr|Q96C32|Q96C32_HUMAN,tr|Q96C32|Q96C32_HUMAN,tr|Q96C32|Q96C32_HUMAN,tr|Q96C32|Q96C32_HUMAN,tr|M0R1V7|M0R1V7_HUMAN,tr|F5H747|F5H747_HUMAN,tr|F5H747|F5H747_HUMAN,tr|F5GXK7|F5GXK7_HUMAN,tr|F5GXK7|F5GXK7_HUMAN,tr|M0R1M6|M0R1M6_HUMAN,tr|F5H6Q2|F5H6Q2_HUMAN,tr|F5H6Q2|F5H6Q2_HUMAN,tr|F5GZ39|F5GZ39_HUMAN,tr|J3QKN0|J3QKN0_HUMAN,tr|J3QKN0|J3QKN0_HUMAN,tr|J3QKN0|J3QKN0_HUMAN,tr|F5H265|F5H265_HUMAN,tr|F5H265|F5H265_HUMAN,tr|A0A2R8Y422|A0A2R8Y422_HUMAN" 48 1048.5177 0.73 59197 5399 2 1048.519612 525.2661 Ubiquitin-40S ribosomal protein S27a OS=Homo sapiens OX=9606 GN=RPS27A PE=1 SV=2 4.37 1559.1 - 2.47E+06 - - - 1.8302 - 1.342 0.317 - 130.7 1 2 0 0.0019 9 0 0 0 9.93E+07 1.36E+08 - - - 2.2328 0.9909 221125_WJC_METTL3_EV_vs_WT_F05.05400.05400.2 0.484 12-May K.MQASIEK[136.11].G "sp|P06748|NPM_HUMAN,tr|E5RI98|E5RI98_HUMAN,tr|A0A7I2YQC0|A0A7I2YQC0_HUMAN,tr|A0A7I2V5J8|A0A7I2V5J8_HUMAN,tr|A0A7I2V5S2|A0A7I2V5S2_HUMAN" 5 813.4146 0.82 59198 5400 2 813.414368 407.7146 Nucleophosmin OS=Homo sapiens OX=9606 GN=NPM1 PE=1 SV=2 5.75 1559.1 - 1.99E+06 - - - -0.2717 - 1.111 0.177 - 83.6 1 2 0 -0.0002 7 0 0 0 2.48E+07 3.02E+07 - - - 0.6818 0.9665 221125_WJC_METTL3_EV_vs_WT_F05.05401.05401.2 0.00693 22-Sep N.VLQGGEGQAPTR[166.11].Q "sp|P24752|THIL_HUMAN,tr|A0A5F9ZHL7|A0A5F9ZHL7_HUMAN,tr|A0A5F9ZHJ7|A0A5F9ZHJ7_HUMAN,tr|A0A5F9ZHH9|A0A5F9ZHH9_HUMAN,tr|A0A5F9ZHJ0|A0A5F9ZHJ0_HUMAN,tr|A0A5F9ZHL1|A0A5F9ZHL1_HUMAN,tr|E9PRQ6|E9PRQ6_HUMAN,tr|H0YEL7|H0YEL7_HUMAN" 8 1221.6341 1.59 59199 5401 2 1221.635079 611.8243 "Acetyl-CoA acetyltransferase, mitochondrial OS=Homo sapiens OX=9606 GN=ACAT1 PE=1 SV=1" 5.97 1559.3 - 409498 - - - 0.7858 - 1.645 0.368 - 193.7 1 1 0 0.001 12 0 0 0 5.34E+06 3.36E+06 - - - 3.0684 0.9998 221125_WJC_METTL3_EV_vs_WT_F05.05406.05406.2 0.000401 14-Oct K.TSEVNC[160.03]YR.C sp|P62633|CNBP_HUMAN 1 1027.4393 0.64 59202 5406 2 1027.439938 514.7269 CCHC-type zinc finger nucleic acid binding protein OS=Homo sapiens OX=9606 GN=CNBP PE=1 SV=1 5.66 1559.9 - 1.06E+07 - - - 0.6268 - 1.901 0.501 - 750 1 2 0 0.0006 8 0 0 0 1.15E+08 1.80E+08 - - - 4.6786 0.9525 221125_WJC_METTL3_EV_vs_WT_F05.05408.05408.2 0.321 12-Jul R.SQIYGSR.Q "sp|P12956|XRCC6_HUMAN,tr|B1AHC9|B1AHC9_HUMAN" 2 809.4032 0.95 59204 5408 2 809.404468 405.7089 X-ray repair cross-complementing protein 6 OS=Homo sapiens OX=9606 GN=XRCC6 PE=1 SV=2 8.46 1560.1 - 1.05E+06 - - - 1.6086 - 1.299 0.014 - 294.1 1 2 0 0.0013 7 0 0 0 1.16E+08 1.23E+08 - - - -0.0271 0.9287 221125_WJC_METTL3_EV_vs_WT_F05.05409.05409.2 0.0522 14-Jun A.ASDDPIEK.V "sp|Q6UWP8|SBSN_HUMAN,tr|K7ESC4|K7ESC4_HUMAN" 2 873.408 999 59205 5409 2 873.408311 437.7113 Suprabasin OS=Homo sapiens OX=9606 GN=SBSN PE=1 SV=2 4.03 1560.2 - 959192 - - - 0.3824 - 1.261 0.334 - 109.9 1 1 0 0.0003 8 0 0 0 5.16E+07 0.00E+00 - - - 2.2072 0.9808 221125_WJC_METTL3_EV_vs_WT_F05.05416.05416.2 0.911 12-Sep R.SQIYGSR[166.11].Q "sp|P12956|XRCC6_HUMAN,tr|B1AHC9|B1AHC9_HUMAN" 2 819.4114 0.98 59210 5416 2 819.411327 410.713 X-ray repair cross-complementing protein 6 OS=Homo sapiens OX=9606 GN=XRCC6 PE=1 SV=2 8.46 1561.1 - 4.54E+06 - - - -0.133 - 1.281 0.048 - 567.2 1 2 0 -0.0001 7 0 0 0 1.16E+08 1.18E+08 - - - 0.1802 0.9917 221125_WJC_METTL3_EV_vs_WT_F05.05417.05417.3 0.828 Oct-44 R.VAAAPASGALRR.L "sp|P06576|ATPB_HUMAN,tr|F8W079|F8W079_HUMAN,tr|F8W0P7|F8W0P7_HUMAN,tr|H0YH81|H0YH81_HUMAN" 4 1138.6571 0.68 59211 5417 3 1138.656639 380.5596 "ATP synthase subunit beta, mitochondrial OS=Homo sapiens OX=9606 GN=ATP5F1B PE=1 SV=3" 12 1561.2 - 1.19E+06 - - - -0.3961 - 1.909 0.162 - 88.1 3 2 0 -0.0005 12 0 0 0 4.14E+07 6.08E+07 - - - 1.9174 0.9994 221125_WJC_METTL3_EV_vs_WT_F05.05419.05419.2 0.0139 16-Jul K.EQGNAYYAK[136.11].K "sp|Q99615|DNJC7_HUMAN,tr|K7ESP1|K7ESP1_HUMAN,tr|A0A6I8PR89|A0A6I8PR89_HUMAN,tr|A0A6I8PIK4|A0A6I8PIK4_HUMAN,tr|K7ELJ8|K7ELJ8_HUMAN,tr|A0A6I8PS32|A0A6I8PS32_HUMAN,tr|A0A6I8PUD4|A0A6I8PUD4_HUMAN,tr|K7EIH8|K7EIH8_HUMAN,tr|A0A6I8PU73|A0A6I8PU73_HUMAN,tr|K7EK03|K7EK03_HUMAN,tr|A0A6I8PU89|A0A6I8PU89_HUMAN" 11 1050.4862 1.8 59213 5419 2 1050.485662 526.2504 DnaJ homolog subfamily C member 7 OS=Homo sapiens OX=9606 GN=DNAJC7 PE=1 SV=2 6.1 1561.2 - 1.78E+06 - - - -0.4874 - 1.371 0.388 - 183.1 1 2 0 -0.0005 9 0 0 0 6.42E+07 3.56E+07 - - - 2.8195 0.9995 221125_WJC_METTL3_EV_vs_WT_F05.05425.05425.2 0.0349 14-Jul R.SYVTTSTR[166.11].T "sp|P08670|VIME_HUMAN,tr|B0YJC4|B0YJC4_HUMAN,tr|A0A1B0GVG8|A0A1B0GVG8_HUMAN,tr|A0A1B0GTT5|A0A1B0GTT5_HUMAN" 4 923.4588 1.72 59217 5425 2 923.458447 462.7367 Vimentin OS=Homo sapiens OX=9606 GN=VIM PE=1 SV=4 8.46 1561.8 - 2.30E+07 - - - -0.3617 - 1.355 0.404 - 169.3 1 2 0 -0.0003 8 0 0 0 1.09E+10 6.33E+09 - - - 2.9411 0.9995 221125_WJC_METTL3_EV_vs_WT_F05.05428.05428.2 3.81E-05 16-Oct K.SEVLGTQSK[136.11].A "sp|O15498|YKT6_HUMAN,tr|A0A7I2V4L6|A0A7I2V4L6_HUMAN" 2 955.5066 3.96 59220 5428 2 955.50901 478.7606 Synaptobrevin homolog YKT6 OS=Homo sapiens OX=9606 GN=YKT6 PE=1 SV=1 5.72 1562 - 1.59E+06 - - - 2.5484 - 2.102 0.434 - 425.1 1 2 0 0.0024 9 0 0 0 1.47E+08 3.71E+07 - - - 4.395 0.9956 221125_WJC_METTL3_EV_vs_WT_F05.05429.05429.2 0.523 14-May K.ASSLEVQK[136.11].A "sp|Q8TCG1|CIP2A_HUMAN,tr|A0A087X211|A0A087X211_HUMAN" 2 868.4745 3.01 59221 5429 2 868.474588 435.2445 Protein CIP2A OS=Homo sapiens OX=9606 GN=CIP2A PE=1 SV=2 6.05 1562.1 - 1.23E+06 - - - 0.0472 - 1.44 0.19 - 112.4 6 2 0 0 8 0 0 0 5.53E+07 1.84E+07 - - - 1.1965 0.9983 221125_WJC_METTL3_EV_vs_WT_F05.05434.05434.2 0.289 12-Jul R.K[136.11]IFVGTK[136.11].G sp|P62701|RS4X_HUMAN 1 807.5189 0.95 59224 5434 2 807.518111 404.7667 "40S ribosomal protein S4, X isoform OS=Homo sapiens OX=9606 GN=RPS4X PE=1 SV=2" 10 1562.8 - 1.04E+07 - - - -1.008 - 1.472 0.244 - 219.4 1 2 0 -0.0008 7 0 0 0 4.71E+08 4.94E+08 - - - 2.068 0.9959 221125_WJC_METTL3_EV_vs_WT_F05.05435.05435.2 0.000618 16-Nov R.QMEVAQANR.H "sp|Q14203|DCTN1_HUMAN,tr|A0A804CDA6|A0A804CDA6_HUMAN,tr|E7EX90|E7EX90_HUMAN,tr|A0A7P0Z4C3|A0A7P0Z4C3_HUMAN,tr|Q6AWB1|Q6AWB1_HUMAN" 5 1045.4975 2.34 59225 5435 2 1045.502345 523.756 Dynactin subunit 1 OS=Homo sapiens OX=9606 GN=DCTN1 PE=1 SV=3 6 1562.8 - 3.39E+06 - - - 4.6552 - 2.112 0.339 - 716 1 2 0 0.0049 9 0 0 0 1.68E+08 7.17E+07 - - - 3.7063 0.9954 221125_WJC_METTL3_EV_vs_WT_F05.05436.05436.2 2.27 12-Jul R.KIFVGTK.G sp|P62701|RS4X_HUMAN 1 791.4905 0.95 59226 5436 2 791.490059 396.7525 "40S ribosomal protein S4, X isoform OS=Homo sapiens OX=9606 GN=RPS4X PE=1 SV=2" 10 1562.8 - 6.76E+06 - - - -0.5888 - 1.441 0.153 - 183.6 2 2 0 -0.0005 7 0 0 0 4.71E+08 4.94E+08 - - - 1.194 0.9845 221125_WJC_METTL3_EV_vs_WT_F05.05442.05442.2 0.207 16-Jul R.GATPPAPPR.A sp|Q6SPF0|SAMD1_HUMAN 1 862.4661 1.61 59230 5442 2 862.464941 432.2403 Sterile alpha motif domain-containing protein 1 OS=Homo sapiens OX=9606 GN=SAMD1 PE=1 SV=1 9.75 1563.5 - 2.06E+06 - - - -1.345 - 1.256 0.116 - 170.8 1 2 0 -0.0012 9 0 0 0 5.33E+07 3.31E+07 - - - 0.5568 0.9988 221125_WJC_METTL3_EV_vs_WT_F05.05443.05443.2 0.107 22-Sep R.GGLSPANDTGAK[136.11].K "sp|P30419|NMT1_HUMAN,tr|A0A7I2V4Y5|A0A7I2V4Y5_HUMAN,tr|B7Z8J4|B7Z8J4_HUMAN,tr|A0A7I2V3X4|A0A7I2V3X4_HUMAN,tr|K7EN42|K7EN42_HUMAN,tr|A0A7I2V539|A0A7I2V539_HUMAN,tr|A0A7I2V3M5|A0A7I2V3M5_HUMAN,tr|A0A7I2V3U5|A0A7I2V3U5_HUMAN" 8 1094.5448 0.49 59231 5443 2 1094.542507 548.2797 Glycylpeptide N-tetradecanoyltransferase 1 OS=Homo sapiens OX=9606 GN=NMT1 PE=1 SV=2 5.84 1563.6 - 1.29E+06 - - - -2.0511 - 1.891 0.307 - 190.9 1 2 0 -0.0022 12 0 0 0 1.52E+07 3.09E+07 - - - 2.9841 0.9997 221125_WJC_METTL3_EV_vs_WT_F05.05444.05444.2 0.0196 16-Sep K.FEETTADGR.K "sp|Q01469|FABP5_HUMAN,tr|I6L8B7|I6L8B7_HUMAN" 2 1024.4462 7.66 59232 5444 2 1024.444933 513.2304 Fatty acid-binding protein 5 OS=Homo sapiens OX=9606 GN=FABP5 PE=1 SV=3 4.14 1563.6 - 8.58E+06 - - - -1.1919 - 1.866 0.402 - 299.6 1 2 0 -0.0012 9 0 0 0 3.21E+08 4.20E+07 - - - 3.8145 0.9998 221125_WJC_METTL3_EV_vs_WT_F05.05446.05446.2 0.000124 16-Nov R.C[160.03]ALC[160.03]AENAK.T "sp|Q9NQ38|ISK5_HUMAN,tr|E7EWP9|E7EWP9_HUMAN,tr|E5RFU9|E5RFU9_HUMAN" 3 1035.4478 36.37 59234 5446 2 1035.447549 518.7312 Serine protease inhibitor Kazal-type 5 OS=Homo sapiens OX=9606 GN=SPINK5 PE=1 SV=2 5.99 1563.9 - 1.23E+06 - - - -0.1951 - 2.185 0.375 - 518.6 1 2 0 -0.0002 9 0 0 0 1.68E+08 4.63E+06 - - - 4.0719 0.9989 221125_WJC_METTL3_EV_vs_WT_F05.05452.05452.2 0.178 18-Sep R.ISAVESQPSR.K "sp|Q9Y520|PRC2C_HUMAN,tr|E7EPN9|E7EPN9_HUMAN" 2 1072.5513 1.65 59238 5452 2 1072.550224 537.2829 Protein PRRC2C OS=Homo sapiens OX=9606 GN=PRRC2C PE=1 SV=4 6 1564.6 - 4.32E+06 - - - -0.9911 - 1.957 0.209 - 277.4 1 2 0 -0.0011 10 0 0 0 6.93E+08 4.20E+08 - - - 2.4585 0.9996 221125_WJC_METTL3_EV_vs_WT_F05.05455.05455.2 0.000133 16-Sep K.TIAPQNAPR.D "sp|Q9NYF8|BCLF1_HUMAN,tr|H0YF00|H0YF00_HUMAN,tr|E9PKI6|E9PKI6_HUMAN,tr|A0A1W2PQ43|A0A1W2PQ43_HUMAN,tr|E9PK91|E9PK91_HUMAN,tr|E9PJA7|E9PJA7_HUMAN,tr|E9PK09|E9PK09_HUMAN,tr|E9PQN2|E9PQN2_HUMAN" 8 966.5247 2.28 59240 5455 2 966.523298 484.2696 Bcl-2-associated transcription factor 1 OS=Homo sapiens OX=9606 GN=BCLAF1 PE=1 SV=2 9.41 1564.9 - 1.61E+07 - - - -1.4288 - 1.668 0.446 - 286.4 1 2 0 -0.0014 9 0 0 0 3.99E+10 1.75E+10 - - - 3.8149 0.9997 221125_WJC_METTL3_EV_vs_WT_F05.05457.05457.2 0.000296 18-Sep R.GGDPEDNDIR[166.11].E sp|O60476|MA1A2_HUMAN 1 1096.4661 1.37 59241 5457 2 1096.464145 549.2403 "Mannosyl-oligosaccharide 1,2-alpha-mannosidase IB OS=Homo sapiens OX=9606 GN=MAN1A2 PE=1 SV=1" 3.84 1565.1 - 1.09E+06 - - - -1.7383 - 1.58 0.521 - 287.6 1 2 0 -0.0019 10 0 0 0 5.15E+07 3.76E+07 - - - 4.1653 0.9994 221125_WJC_METTL3_EV_vs_WT_F05.05465.05465.2 0.01 14-Jul R.SYVTTSTR.T "sp|P08670|VIME_HUMAN,tr|B0YJC4|B0YJC4_HUMAN,tr|A0A1B0GVG8|A0A1B0GVG8_HUMAN,tr|A0A1B0GTT5|A0A1B0GTT5_HUMAN" 4 913.4505 1.71 59246 5465 2 913.448821 457.7325 Vimentin OS=Homo sapiens OX=9606 GN=VIM PE=1 SV=4 8.46 1566 - 4.38E+08 - - - -1.8501 - 1.44 0.465 - 157.8 1 2 0 -0.0017 8 0 0 0 1.09E+10 6.34E+09 - - - 3.5747 0.96 221125_WJC_METTL3_EV_vs_WT_F05.05467.05467.2 0.109 14-Jul R.DTTLETEK.A "sp|Q6KC79|NIPBL_HUMAN,tr|A0A590UJS4|A0A590UJS4_HUMAN" 2 935.4448 2.34 59247 5467 2 935.438567 468.7297 Nipped-B-like protein OS=Homo sapiens OX=9606 GN=NIPBL PE=1 SV=2 4.14 1566.2 - 1.20E+06 - - - -6.6172 - 1.586 0.306 - 210.3 1 2 0 -0.0062 8 0 0 0 5.86E+07 2.50E+07 - - - 2.6902 0.9871 221125_WJC_METTL3_EV_vs_WT_F05.05469.05469.2 0.0261 16-Jul R.STAPASLSR.S "sp|P35658|NU214_HUMAN,tr|A0A0A0MSW3|A0A0A0MSW3_HUMAN,tr|A0A494C1F2|A0A494C1F2_HUMAN" 3 888.4665 1.69 59248 5469 2 888.464261 445.2405 Nuclear pore complex protein Nup214 OS=Homo sapiens OX=9606 GN=NUP214 PE=1 SV=2 9.47 1566.4 - 6.99E+06 - - - -2.5144 - 1.302 0.194 - 203.4 1 2 0 -0.0022 9 0 0 0 6.07E+08 3.59E+08 - - - 1.2367 0.9437 221125_WJC_METTL3_EV_vs_WT_F05.05481.05481.2 0.263 14-Aug K.AGDAPLVK.V "sp|Q9HC56|PCDH9_HUMAN,tr|Q5VT82|Q5VT82_HUMAN,tr|B7ZM79|B7ZM79_HUMAN" 3 769.4334 10.03 59254 5481 2 769.436147 385.724 Protocadherin-9 OS=Homo sapiens OX=9606 GN=PCDH9 PE=1 SV=2 5.88 1567.8 - 2.77E+06 - - - 3.565 - 1.522 0.057 - 288.2 1 2 0 0.0027 8 0 0 0 4.18E+07 4.17E+06 - - - 0.7279 0.9909 221125_WJC_METTL3_EV_vs_WT_F05.05490.05490.2 0.00284 16-Sep R.SAVPPGADK[136.11].K "sp|P46783|RS10_HUMAN,tr|F6U211|F6U211_HUMAN,tr|A0A1W2PQS6|A0A1W2PQS6_HUMAN,tr|A0A2R8YFH6|A0A2R8YFH6_HUMAN,tr|A0A2R8Y7H1|A0A2R8Y7H1_HUMAN,tr|S4R435|S4R435_HUMAN" 6 848.4483 1.53 59257 5490 2 848.444638 425.2314 40S ribosomal protein S10 OS=Homo sapiens OX=9606 GN=RPS10 PE=1 SV=1 5.55 1569 - 3.36E+06 - - - -4.3538 - 1.553 0.312 - 277.1 1 2 0 -0.0037 9 0 0 0 5.84E+08 3.81E+08 - - - 2.6178 0.9984 221125_WJC_METTL3_EV_vs_WT_F05.05492.05492.2 7.89E-05 20-Oct R.GGNGLAPGEDR.F "sp|Q86SF2|GALT7_HUMAN,tr|E9PBY3|E9PBY3_HUMAN" 2 1041.4839 1.43 59259 5492 2 1041.479722 521.7492 N-acetylgalactosaminyltransferase 7 OS=Homo sapiens OX=9606 GN=GALNT7 PE=1 SV=1 4.37 1569.3 - 2.09E+06 - - - -4.0461 - 2.035 0.457 - 360.4 1 2 0 -0.0042 11 0 0 0 1.26E+08 8.83E+07 - - - 4.3371 0.9928 221125_WJC_METTL3_EV_vs_WT_F05.05505.05505.2 0.363 16-Aug R.STAPASLSR[166.11].S "sp|P35658|NU214_HUMAN,tr|A0A0A0MSW3|A0A0A0MSW3_HUMAN,tr|A0A494C1F2|A0A494C1F2_HUMAN" 3 898.4748 1.65 59264 5505 2 898.473545 450.2447 Nuclear pore complex protein Nup214 OS=Homo sapiens OX=9606 GN=NUP214 PE=1 SV=2 9.47 1570.8 - 4.98E+06 - - - -1.3579 - 1.31 0.173 - 258.5 1 2 0 -0.0012 9 0 0 0 6.11E+08 3.70E+08 - - - 1.0996 0.9283 221125_WJC_METTL3_EV_vs_WT_F05.05520.05520.2 0.00558 16-Sep S.SVLAGGSC[160.03]R.A "sp|P02533|K1C14_HUMAN,sp|P08779|K1C16_HUMAN,tr|K7ENV3|K7ENV3_HUMAN" 3 905.4389 0.08 59273 5520 2 905.436818 453.7267 "Keratin, type I cytoskeletal 14 OS=Homo sapiens OX=9606 GN=KRT14 PE=1 SV=4" 7.96 1572.5 - 2.45E+06 - - - -2.2994 - 1.67 0.344 - 325 1 1 0 -0.0021 9 0 0 0 1.08E+08 1.35E+09 - - - 3.0648 0.9996 221125_WJC_METTL3_EV_vs_WT_F05.05522.05522.2 0.00572 16-Aug R.FDAQTGADR[166.11].E sp|P43686|PRS6B_HUMAN 1 989.4442 1.01 59274 5522 2 989.443255 495.7294 26S proteasome regulatory subunit 6B OS=Homo sapiens OX=9606 GN=PSMC4 PE=1 SV=2 4.21 1572.7 - 1.84E+06 - - - -0.948 - 1.467 0.427 - 179.8 1 2 0 -0.0009 9 0 0 0 5.58E+07 5.52E+07 - - - 3.3032 0.9976 221125_WJC_METTL3_EV_vs_WT_F05.05530.05530.2 0.000503 20-Sep R.AALQEEEQASK[136.11].Q "sp|O00139|KIF2A_HUMAN,tr|A0A6Q8PFA6|A0A6Q8PFA6_HUMAN,tr|A0A6Q8PGG1|A0A6Q8PGG1_HUMAN,tr|A0A6Q8PGH7|A0A6Q8PGH7_HUMAN,tr|A0A6Q8PG37|A0A6Q8PG37_HUMAN,tr|A0A6Q8PH57|A0A6Q8PH57_HUMAN" 6 1210.5921 1.52 59277 5530 2 1210.587107 606.3033 Kinesin-like protein KIF2A OS=Homo sapiens OX=9606 GN=KIF2A PE=1 SV=3 4.25 1573.7 - 641055 - - - -4.1211 - 2.019 0.396 - 249.3 1 2 0 -0.005 11 0 0 0 9.01E+07 5.93E+07 - - - 3.865 0.8735 221125_WJC_METTL3_EV_vs_WT_F05.05537.05537.2 0.413 12-Jul K.LK[136.11]DEVLK[136.11].E "sp|Q14203|DCTN1_HUMAN,sp|P15880|RS2_HUMAN,tr|I3L404|I3L404_HUMAN,tr|A0A804CDA6|A0A804CDA6_HUMAN,tr|E9PM36|E9PM36_HUMAN,tr|E9PQD7|E9PQD7_HUMAN,tr|E9PPT0|E9PPT0_HUMAN,tr|E7EX90|E7EX90_HUMAN,tr|E9PMM9|E9PMM9_HUMAN,tr|A0A7P0Z4C3|A0A7P0Z4C3_HUMAN,tr|E7EWF7|E7EWF7_HUMAN" 11 859.535 2.55 59281 5537 2 859.535062 430.7748 Dynactin subunit 1 OS=Homo sapiens OX=9606 GN=DCTN1 PE=1 SV=3 6.07 1574.5 - 434162 - - - 0.1082 - 1.625 0.002 - 169.1 2 2 1 0.0001 7 0 0 0 5.54E+07 2.18E+07 - - - 0.4596 0.9907 221125_WJC_METTL3_EV_vs_WT_F05.05538.05538.2 6.60E-05 16-Sep A.QAASSYGVR.A sp|Q96PK6|RBM14_HUMAN 1 937.4617 1.42 59282 5538 2 937.461467 469.7381 RNA-binding protein 14 OS=Homo sapiens OX=9606 GN=RBM14 PE=1 SV=2 8.75 1574.6 - 961063 - - - -0.2955 - 1.835 0.492 - 422.3 1 1 0 -0.0003 9 0 0 0 2.83E+07 2.00E+07 - - - 4.431 0.9985 221125_WJC_METTL3_EV_vs_WT_F05.05541.05541.2 0.221 16-Jul K.EGVVAAAEK[136.11].T "sp|Q16143|SYUB_HUMAN,sp|P37840|SYUA_HUMAN,tr|A0A669KB41|A0A669KB41_HUMAN,tr|G4Y816|G4Y816_HUMAN,tr|D6RA31|D6RA31_HUMAN,tr|A0A669KBH5|A0A669KBH5_HUMAN,tr|H6UYS7|H6UYS7_HUMAN,tr|E7EPV7|E7EPV7_HUMAN" 8 880.4745 1.42 59283 5541 2 880.474711 441.2445 Beta-synuclein OS=Homo sapiens OX=9606 GN=SNCB PE=1 SV=1 4.53 1575 - 874850 - - - 0.1863 - 1.668 0.204 - 174.7 1 2 0 0.0002 9 0 0 0 3.75E+07 2.65E+07 - - - 2.0279 0.9866 221125_WJC_METTL3_EV_vs_WT_F05.05543.05543.2 0.0897 16-Jun K.IEEQINSTK.Y tr|A0A1B0GTZ1|A0A1B0GTZ1_HUMAN 1 1060.5401 1.59 59284 5543 2 1060.538228 531.2773 Synaptotagmin-14 OS=Homo sapiens OX=9606 GN=SYT14 PE=4 SV=1 4.53 1575.2 - 740915 - - - -1.7218 - 1.377 0.157 - 78.1 5 2 0 -0.0018 9 0 0 0 2.47E+07 1.56E+07 - - - 0.8133 0.9996 221125_WJC_METTL3_EV_vs_WT_F05.05545.05545.2 5.18E-05 20-Oct R.AALQEEEQASK.Q "sp|O00139|KIF2A_HUMAN,tr|A0A6Q8PFA6|A0A6Q8PFA6_HUMAN,tr|A0A6Q8PGG1|A0A6Q8PGG1_HUMAN,tr|A0A6Q8PGH7|A0A6Q8PGH7_HUMAN,tr|A0A6Q8PG37|A0A6Q8PG37_HUMAN,tr|A0A6Q8PH57|A0A6Q8PH57_HUMAN" 6 1202.5779 1.52 59286 5545 2 1202.574639 602.2962 Kinesin-like protein KIF2A OS=Homo sapiens OX=9606 GN=KIF2A PE=1 SV=3 4.25 1575.5 - 1.64E+06 - - - -2.7083 - 2.206 0.491 - 280.7 1 2 0 -0.0033 11 0 0 0 9.01E+07 5.93E+07 - - - 4.8068 0.9979 221125_WJC_METTL3_EV_vs_WT_F05.05546.05546.2 0.0166 14-Jun R.DSYGGPPR[166.11].R "sp|Q96E39|RMXL1_HUMAN,sp|P38159|RBMX_HUMAN,tr|H3BUY5|H3BUY5_HUMAN,tr|H3BT71|H3BT71_HUMAN,tr|H0Y6E7|H0Y6E7_HUMAN" 5 857.3907 1.45 59287 5546 2 857.389384 429.7026 "RNA binding motif protein, X-linked-like-1 OS=Homo sapiens OX=9606 GN=RBMXL1 PE=1 SV=1" 5.84 1575.6 - 962385 - - - -1.5361 - 1.251 0.324 - 124.8 1 2 0 -0.0013 8 0 0 0 7.42E+08 5.13E+08 - - - 2.1091 0.9988 221125_WJC_METTL3_EV_vs_WT_F05.05552.05552.2 0.000698 16-Sep K.EGVVAAAEK.T "sp|Q16143|SYUB_HUMAN,sp|P37840|SYUA_HUMAN,tr|A0A669KB41|A0A669KB41_HUMAN,tr|G4Y816|G4Y816_HUMAN,tr|D6RA31|D6RA31_HUMAN,tr|A0A669KBH5|A0A669KBH5_HUMAN,tr|H6UYS7|H6UYS7_HUMAN,tr|E7EPV7|E7EPV7_HUMAN" 8 872.4603 1.44 59289 5552 2 872.457447 437.2374 Beta-synuclein OS=Homo sapiens OX=9606 GN=SNCB PE=1 SV=1 4.53 1576.3 - 1.48E+06 - - - -3.3239 - 1.949 0.405 - 259.2 1 2 0 -0.0029 9 0 0 0 3.75E+07 2.60E+07 - - - 3.962 0.9712 221125_WJC_METTL3_EV_vs_WT_F05.05554.05554.2 1.23 16-Sep R.QLEGAEINK.S sp|Q8N4N8|KIF2B_HUMAN 1 1000.5189 1.54 59290 5554 2 1000.51729 501.2667 Kinesin-like protein KIF2B OS=Homo sapiens OX=9606 GN=KIF2B PE=1 SV=3 4.53 1576.6 - 820052 - - - -1.6342 - 1.491 0.008 - 189.9 1 2 0 -0.0016 9 0 0 0 5.87E+07 3.82E+07 - - - 0.2552 0.9995 221125_WJC_METTL3_EV_vs_WT_F05.05561.05561.2 0.000366 18-Sep R.VDVADQAQDK.D "sp|P23588|IF4B_HUMAN,tr|E7EX17|E7EX17_HUMAN,tr|F8VSC7|F8VSC7_HUMAN,tr|F8VYE9|F8VYE9_HUMAN,tr|F8VX11|F8VX11_HUMAN,tr|F8W0K0|F8W0K0_HUMAN,tr|F8VP89|F8VP89_HUMAN" 7 1087.5146 3.62 59295 5561 2 1087.516081 544.7646 Eukaryotic translation initiation factor 4B OS=Homo sapiens OX=9606 GN=EIF4B PE=1 SV=2 3.93 1577.5 - 360599 - - - 1.3912 - 1.993 0.359 - 256.8 1 2 0 0.0015 10 0 0 0 1.18E+07 3.27E+06 - - - 3.6171 0.9964 221125_WJC_METTL3_EV_vs_WT_F05.05563.05563.2 0.00723 16-Aug K.TYGQSTYSR.Q "sp|P35998|PRS7_HUMAN,tr|C9JX88|C9JX88_HUMAN,tr|C9JLS9|C9JLS9_HUMAN" 3 1061.4778 0.25 59297 5563 2 1061.481092 531.7462 26S proteasome regulatory subunit 7 OS=Homo sapiens OX=9606 GN=PSMC2 PE=1 SV=3 8.25 1577.6 - 645431 - - - 3.1126 - 1.493 0.334 - 183.3 1 2 0 0.0033 9 0 0 0 3.70E+07 1.46E+08 - - - 2.6664 0.9995 221125_WJC_METTL3_EV_vs_WT_F05.05571.05571.2 0.0387 16-Sep R.LSYNTASNK.T sp|P49207|RL34_HUMAN 1 996.4876 0.83 59300 5571 2 996.486023 499.2511 60S ribosomal protein L34 OS=Homo sapiens OX=9606 GN=RPL34 PE=1 SV=3 8.59 1578.6 - 1.45E+06 - - - -1.6066 - 1.773 0.381 - 225.4 1 2 0 -0.0016 9 0 0 0 8.72E+07 1.05E+08 - - - 3.5113 0.9994 221125_WJC_METTL3_EV_vs_WT_F05.05580.05580.2 0.00177 14-Jun R.ASFNNPDR[166.11].A "sp|P54727|RD23B_HUMAN,tr|H0Y579|H0Y579_HUMAN" 2 929.4231 1.67 59304 5580 2 929.42337 465.7188 UV excision repair protein RAD23 homolog B OS=Homo sapiens OX=9606 GN=RAD23B PE=1 SV=1 5.88 1579.8 - 964257 - - - 0.3292 - 1.399 0.386 - 144.1 1 2 0 0.0003 8 0 0 0 6.70E+07 4.01E+07 - - - 2.9045 0.9993 221125_WJC_METTL3_EV_vs_WT_F05.05585.05585.2 0.00321 18-Oct R.ALSAVSTQQK.K "sp|Q08379|GOGA2_HUMAN,tr|A0A6Q8KRG2|A0A6Q8KRG2_HUMAN,tr|H0Y7B8|H0Y7B8_HUMAN,tr|B7ZC06|B7ZC06_HUMAN" 4 1031.5611 1.85 59307 5585 2 1031.562055 516.7878 Golgin subfamily A member 2 OS=Homo sapiens OX=9606 GN=GOLGA2 PE=1 SV=3 8.8 1580.3 - 750498 - - - 0.9025 - 2.037 0.264 - 317.9 1 2 0 0.0009 10 0 0 0 2.35E+07 1.27E+07 - - - 2.9766 0.9918 221125_WJC_METTL3_EV_vs_WT_F05.05587.05587.2 0.0446 16-Aug R.C[160.03]SEPPPVAR[166.11].L "sp|O14654|IRS4_HUMAN,tr|A0A804CF45|A0A804CF45_HUMAN" 2 1021.489 0.72 59309 5587 2 1021.486147 511.7518 Insulin receptor substrate 4 OS=Homo sapiens OX=9606 GN=IRS4 PE=1 SV=1 5.99 1580.6 - 609302 - - - -2.8272 - 1.412 0.232 - 261.5 1 2 0 -0.0029 9 0 0 0 1.53E+07 2.13E+07 - - - 1.7518 0.9986 221125_WJC_METTL3_EV_vs_WT_F05.05591.05591.2 0.0246 12-Jul R.STDFTSR.D sp|O43143|DHX15_HUMAN 1 812.3664 1.45 59311 5591 2 812.365294 407.1905 Pre-mRNA-splicing factor ATP-dependent RNA helicase DHX15 OS=Homo sapiens OX=9606 GN=DHX15 PE=1 SV=2 5.55 1581.1 - 458012 - - - -1.4193 - 1.592 0.256 - 310.8 1 2 0 -0.0012 7 0 0 0 1.23E+08 8.46E+07 - - - 2.4048 0.8223 221125_WJC_METTL3_EV_vs_WT_F05.05592.05592.2 2.45 16-May R.YESQNTELK[136.11].T "sp|Q9H5H4|ZN768_HUMAN,tr|H3BS42|H3BS42_HUMAN" 2 1118.5335 2.95 59312 5592 2 1118.534472 560.274 Zinc finger protein 768 OS=Homo sapiens OX=9606 GN=ZNF768 PE=1 SV=2 4.53 1581.2 - 334420 - - - 0.852 - 0.817 0.05 - 54.2 1 2 0 0.001 9 0 0 0 4.10E+07 1.39E+07 - - - -1.1747 0.9875 221125_WJC_METTL3_EV_vs_WT_F05.05601.05601.2 0.806 16-Jul R.SAVPPGADK.K "sp|P46783|RS10_HUMAN,tr|F6U211|F6U211_HUMAN,tr|A0A1W2PQS6|A0A1W2PQS6_HUMAN,tr|A0A2R8YFH6|A0A2R8YFH6_HUMAN,tr|A0A2R8Y7H1|A0A2R8Y7H1_HUMAN,tr|S4R435|S4R435_HUMAN" 6 840.4341 1.53 59316 5601 2 840.431723 421.2243 40S ribosomal protein S10 OS=Homo sapiens OX=9606 GN=RPS10 PE=1 SV=1 5.55 1582.4 - 3.54E+06 - - - -2.8664 - 1.262 0.235 - 154.2 1 2 0 -0.0024 9 0 0 0 5.84E+08 3.81E+08 - - - 1.4492 0.9891 221125_WJC_METTL3_EV_vs_WT_F05.05606.05606.2 0.0601 12-Aug K.K[136.11]VEDMMK[136.11].K sp|P13639|EF2_HUMAN 1 895.4478 0.18 59319 5606 2 895.44533 448.7312 Elongation factor 2 OS=Homo sapiens OX=9606 GN=EEF2 PE=1 SV=4 6.07 1583 - 1.25E+06 - - - -2.7696 - 1.781 0.086 - 241.1 1 2 0 -0.0025 7 0 0 0 2.21E+07 1.22E+08 - - - 1.5042 0.9991 221125_WJC_METTL3_EV_vs_WT_F05.05610.05610.2 0.000546 14-Aug R.ASFNNPDR.A "sp|P54727|RD23B_HUMAN,tr|H0Y579|H0Y579_HUMAN" 2 919.4148 1.55 59320 5610 2 919.412924 460.7147 UV excision repair protein RAD23 homolog B OS=Homo sapiens OX=9606 GN=RAD23B PE=1 SV=1 5.88 1583.6 - 1.26E+06 - - - -2.0339 - 1.535 0.39 - 265.3 1 2 0 -0.0019 8 0 0 0 6.20E+07 4.00E+07 - - - 3.2134 0.9946 221125_WJC_METTL3_EV_vs_WT_F05.05611.05611.2 0.00553 14-Jun R.SIYC[160.03]SSQR[166.11].S sp|Q5JSZ5|PRC2B_HUMAN 1 1009.4526 12.21 59321 5611 2 1009.44975 505.7336 Protein PRRC2B OS=Homo sapiens OX=9606 GN=PRRC2B PE=1 SV=2 7.94 1583.7 - 482883 - - - -2.8728 - 1.126 0.37 - 124.1 1 2 0 -0.0029 8 0 0 0 1.03E+09 8.41E+07 - - - 2.1308 0.9996 221125_WJC_METTL3_EV_vs_WT_F05.05613.05613.2 4.26E-05 20-Sep R.STVDAPTAAGR[166.11].G sp|Q99832|TCPH_HUMAN 1 1054.5283 0.6 59322 5613 2 1054.526427 528.2714 T-complex protein 1 subunit eta OS=Homo sapiens OX=9606 GN=CCT7 PE=1 SV=2 5.55 1583.9 - 2.17E+06 - - - -1.7354 - 1.966 0.43 - 283.6 1 2 0 -0.0018 11 0 0 0 6.83E+07 1.14E+08 - - - 4.0451 0.9991 221125_WJC_METTL3_EV_vs_WT_F05.05615.05615.2 0.0203 16-Aug K.TIAPQNAPR[166.11].D "sp|Q9NYF8|BCLF1_HUMAN,tr|H0YF00|H0YF00_HUMAN,tr|E9PKI6|E9PKI6_HUMAN,tr|A0A1W2PQ43|A0A1W2PQ43_HUMAN,tr|E9PK91|E9PK91_HUMAN,tr|E9PJA7|E9PJA7_HUMAN,tr|E9PK09|E9PK09_HUMAN,tr|E9PQN2|E9PQN2_HUMAN" 8 976.5329 2.28 59323 5615 2 976.531312 489.2738 Bcl-2-associated transcription factor 1 OS=Homo sapiens OX=9606 GN=BCLAF1 PE=1 SV=2 9.41 1584.1 - 2.13E+07 - - - -1.6763 - 1.618 0.346 - 194.2 1 2 0 -0.0016 9 0 0 0 3.99E+10 1.75E+10 - - - 2.9882 0.8534 221125_WJC_METTL3_EV_vs_WT_F05.05617.05617.2 0.194 16-Aug L.LQQVDTSTR.T sp|P04264|K2C1_HUMAN 1 1046.5356 21.02 59324 5617 2 1046.533538 524.2751 "Keratin, type II cytoskeletal 1 OS=Homo sapiens OX=9606 GN=KRT1 PE=1 SV=6" 5.84 1584.3 - 1.68E+06 - - - -2.0057 - 1.538 0.25 - 201 1 1 0 -0.0021 9 0 0 0 5.57E+07 2.65E+06 - - - 2.1323 0.9802 221125_WJC_METTL3_EV_vs_WT_F05.05618.05618.2 0.254 16-May R.ASYTPSPAR.S sp|Q96DF8|ESS2_HUMAN 1 948.4665 2.51 59325 5618 2 948.465472 475.2405 Splicing factor ESS-2 homolog OS=Homo sapiens OX=9606 GN=ESS2 PE=1 SV=1 8.79 1584.4 - 1.16E+06 - - - -1.0786 - 1.077 0.16 - 82.3 2 2 0 -0.001 9 0 0 0 2.76E+08 1.10E+08 - - - 0.3026 0.9944 221125_WJC_METTL3_EV_vs_WT_F05.05619.05619.2 0.0237 16-Jul R.YESQNTELK.T "sp|Q9H5H4|ZN768_HUMAN,tr|H3BS42|H3BS42_HUMAN" 2 1110.5193 3.45 59326 5619 2 1110.52133 556.2669 Zinc finger protein 768 OS=Homo sapiens OX=9606 GN=ZNF768 PE=1 SV=2 4.53 1584.6 - 342446 - - - 1.8109 - 1.231 0.259 - 106.4 1 2 0 0.002 9 0 0 0 4.81E+07 1.39E+07 - - - 1.5546 0.9998 221125_WJC_METTL3_EV_vs_WT_F05.05620.05620.2 1.22E-05 16-Aug R.VC[160.03]DNC[160.03]YEAR.N "sp|Q9HBF4|ZFYV1_HUMAN,tr|G3V5N8|G3V5N8_HUMAN" 2 1185.4543 0.46 59327 5620 2 1185.453412 593.7344 Zinc finger FYVE domain-containing protein 1 OS=Homo sapiens OX=9606 GN=ZFYVE1 PE=1 SV=1 4.37 1584.7 - 146119 - - - -0.7432 - 1.664 0.545 - 168.8 1 2 0 -0.0009 9 0 0 0 9.28E+06 2.04E+07 - - - 4.5393 0.9948 221125_WJC_METTL3_EV_vs_WT_F05.05625.05625.2 0.0821 14-Jul R.QIYEEANK.T "sp|Q9BZJ0|CRNL1_HUMAN,tr|Q5JY65|Q5JY65_HUMAN" 2 993.4767 1.41 59330 5625 2 993.475154 497.7456 Crooked neck-like protein 1 OS=Homo sapiens OX=9606 GN=CRNKL1 PE=1 SV=4 4.53 1585.3 - 1.12E+06 - - - -1.5813 - 1.264 0.228 - 146.8 1 2 0 -0.0016 8 0 0 0 3.25E+07 2.30E+07 - - - 1.4311 0.9993 221125_WJC_METTL3_EV_vs_WT_F05.05626.05626.2 0.00227 14-Jul R.SIYC[160.03]SSQR.S sp|Q5JSZ5|PRC2B_HUMAN 1 999.4444 1.04 59331 5626 2 999.44255 500.7295 Protein PRRC2B OS=Homo sapiens OX=9606 GN=PRRC2B PE=1 SV=2 7.94 1585.4 - 1.10E+06 - - - -1.831 - 1.292 0.48 - 181.1 1 2 0 -0.0018 8 0 0 0 6.61E+07 6.36E+07 - - - 3.3584 0.9005 221125_WJC_METTL3_EV_vs_WT_F05.05628.05628.2 10.1 14-May R.RLEPAIQK.F "sp|P56962|STX17_HUMAN,tr|E9PJV6|E9PJV6_HUMAN,tr|E9PIC2|E9PIC2_HUMAN,tr|E9PJW1|E9PJW1_HUMAN,tr|E9PQU9|E9PQU9_HUMAN" 5 953.5658 0.86 59333 5628 2 953.565084 477.7902 Syntaxin-17 OS=Homo sapiens OX=9606 GN=STX17 PE=1 SV=2 8.75 1585.7 - 430954 - - - -0.7666 - 1.148 0.015 - 94.8 8 2 0 -0.0007 8 0 0 0 1.69E+07 1.97E+07 - - - -0.8356 0.9991 221125_WJC_METTL3_EV_vs_WT_F05.05635.05635.2 0.052 14-Aug K.QTLGVTQK[136.11].- sp|Q6NUK1|SCMC1_HUMAN 1 881.5062 0.93 59335 5635 2 881.50582 441.7604 Calcium-binding mitochondrial carrier protein SCaMC-1 OS=Homo sapiens OX=9606 GN=SLC25A24 PE=1 SV=2 8.75 1586.7 - 544312 - - - -0.4107 - 1.502 0.3 - 256.8 1 2 0 -0.0004 8 0 0 0 1.38E+07 1.48E+07 - - - 2.4836 0.9811 221125_WJC_METTL3_EV_vs_WT_F05.05636.05636.2 0.00266 14-Sep K.QTLGVTQK.- sp|Q6NUK1|SCMC1_HUMAN 1 873.492 0.78 59336 5636 2 873.496537 437.7533 Calcium-binding mitochondrial carrier protein SCaMC-1 OS=Homo sapiens OX=9606 GN=SLC25A24 PE=1 SV=2 8.75 1586.8 - 583670 - - - 5.2147 - 1.932 0.204 - 289 1 2 0 0.0046 8 0 0 0 1.38E+07 1.76E+07 - - - 2.5325 0.9864 221125_WJC_METTL3_EV_vs_WT_F05.05646.05646.2 0.245 16-Mar K.ELEQEEEER.K "sp|Q92793|CBP_HUMAN,sp|Q09472|EP300_HUMAN,tr|A0A669KB12|A0A669KB12_HUMAN" 3 1189.5099 999 59341 5646 2 1189.509563 595.7622 CREB-binding protein OS=Homo sapiens OX=9606 GN=CREBBP PE=1 SV=3 3.9 1588.1 - 72011.5 - - - -0.2631 - 0.857 0.275 - 28.6 3 2 0 -0.0003 9 0 0 0 3.18E+06 0.00E+00 - - - 0.4125 0.9378 221125_WJC_METTL3_EV_vs_WT_F05.05647.05647.2 0.422 16-Sep L.TDLSNSLEK.C sp|Q14789|GOGB1_HUMAN 1 1005.4979 76.33 59342 5647 2 1005.497896 503.7562 Golgin subfamily B member 1 OS=Homo sapiens OX=9606 GN=GOLGB1 PE=1 SV=2 4.37 1588.1 - 2.94E+06 - - - 0.0408 - 1.865 0.195 - 237.6 1 1 0 0 9 0 0 0 1.22E+08 1.60E+06 - - - 2.2844 0.9823 221125_WJC_METTL3_EV_vs_WT_F05.05648.05648.2 0.000247 16-Oct A.APDQDEIQR.L "sp|P10619|PPGB_HUMAN,tr|A0A7I2V3M2|A0A7I2V3M2_HUMAN,tr|X6R8A1|X6R8A1_HUMAN,tr|A0A7I2V4Q9|A0A7I2V4Q9_HUMAN,tr|A0A7I2V2E2|A0A7I2V2E2_HUMAN,tr|U3KQ41|U3KQ41_HUMAN,tr|A0A7I2V3B2|A0A7I2V3B2_HUMAN,tr|A0A7I2V4K5|A0A7I2V4K5_HUMAN,tr|A0A7I2V4D1|A0A7I2V4D1_HUMAN,tr|A0A7I2YQT8|A0A7I2YQT8_HUMAN,tr|X6R5C5|X6R5C5_HUMAN,tr|A0A7I2V504|A0A7I2V504_HUMAN,tr|Q5JZH0|Q5JZH0_HUMAN,tr|U3KQU6|U3KQU6_HUMAN,tr|A0A7I2V4R8|A0A7I2V4R8_HUMAN,tr|U3KQF1|U3KQF1_HUMAN" 16 1070.4993 77.51 59343 5648 2 1070.50006 536.2569 Lysosomal protective protein OS=Homo sapiens OX=9606 GN=CTSA PE=1 SV=2 4.03 1588.3 - 570926 - - - 0.7548 - 1.69 0.437 - 379.5 1 1 0 0.0008 9 0 0 0 4.66E+07 6.01E+05 - - - 3.7865 0.9874 221125_WJC_METTL3_EV_vs_WT_F05.05651.05651.2 0.649 12-Jun K.KVEDMMK.K sp|P13639|EF2_HUMAN 1 879.4194 0.2 59344 5651 2 879.420069 440.717 Elongation factor 2 OS=Homo sapiens OX=9606 GN=EEF2 PE=1 SV=4 6.07 1588.7 - 490437 - - - 0.7494 - 1.17 0.141 - 134.3 1 2 0 0.0007 7 0 0 0 2.21E+07 1.10E+08 - - - 0.5797 0.9953 221125_WJC_METTL3_EV_vs_WT_F05.05652.05652.2 0.85 14-Jul R.EIEQVNER.V "sp|P0C1Z6|TFPT_HUMAN,tr|A8MTQ3|A8MTQ3_HUMAN,tr|A0A0G2JP55|A0A0G2JP55_HUMAN" 3 1015.4934 0.46 59345 5652 2 1015.491689 508.754 TCF3 fusion partner OS=Homo sapiens OX=9606 GN=TFPT PE=1 SV=1 4.25 1588.8 - 472183 - - - -1.7223 - 1.388 0.209 - 239.7 1 2 0 -0.0017 8 0 0 0 1.24E+07 2.70E+07 - - - 1.5729 0.9996 221125_WJC_METTL3_EV_vs_WT_F05.05656.05656.2 0.00399 14-Jul R.DSYGGPPR.R "sp|Q96E39|RMXL1_HUMAN,sp|P38159|RBMX_HUMAN,tr|H3BUY5|H3BUY5_HUMAN,tr|H3BT71|H3BT71_HUMAN,tr|H0Y6E7|H0Y6E7_HUMAN" 5 847.3824 1.46 59347 5656 2 847.382872 424.6985 "RNA binding motif protein, X-linked-like-1 OS=Homo sapiens OX=9606 GN=RBMXL1 PE=1 SV=1" 5.84 1589.3 - 1.72E+07 - - - 0.5204 - 1.371 0.447 - 162.7 1 2 0 0.0004 8 0 0 0 7.50E+08 5.13E+08 - - - 3.2941 0.9951 221125_WJC_METTL3_EV_vs_WT_F05.05658.05658.2 0.0206 18-Jun K.LSSETYSQAK[136.11].D sp|Q08J23|NSUN2_HUMAN 1 1120.5492 0.74 59349 5658 2 1120.545679 561.2819 RNA cytosine C(5)-methyltransferase NSUN2 OS=Homo sapiens OX=9606 GN=NSUN2 PE=1 SV=2 6 1589.5 - 250081 - - - -3.1145 - 1.389 0.326 - 82.4 1 2 0 -0.0035 10 0 0 0 4.23E+07 5.69E+07 - - - 2.3649 0.9977 221125_WJC_METTL3_EV_vs_WT_F05.05663.05663.2 0.0102 16-Jul K.TSPYDSGPR.L sp|O75063|XYLK_HUMAN 1 978.4407 1.12 59352 5663 2 978.441232 490.2276 Glycosaminoglycan xylosylkinase OS=Homo sapiens OX=9606 GN=FAM20B PE=1 SV=1 5.5 1590.1 - 1.27E+06 - - - 0.5703 - 1.086 0.335 - 137.7 1 2 0 0.0006 9 0 0 0 2.72E+07 2.42E+07 - - - 1.7538 0.9502 221125_WJC_METTL3_EV_vs_WT_F05.05670.05670.2 0.829 18-Aug K.ASGTLPSQPK.V "sp|Q9NRA8|4ET_HUMAN,tr|B1AKL4|B1AKL4_HUMAN,tr|B0QYZ7|B0QYZ7_HUMAN" 3 984.524 1.64 59357 5670 2 984.528316 493.2693 Eukaryotic translation initiation factor 4E transporter OS=Homo sapiens OX=9606 GN=EIF4ENIF1 PE=1 SV=2 8.8 1590.9 - 972281 - - - 4.3737 - 1.503 0.162 - 52.6 2 2 0 0.0043 10 0 0 0 2.42E+07 1.48E+07 - - - 1.2391 0.9994 221125_WJC_METTL3_EV_vs_WT_F05.05671.05671.2 0.11 14-Sep K.DAEALSQR[166.11].L sp|P35580|MYH10_HUMAN 1 898.4384 0.93 59358 5671 2 898.439038 450.2265 Myosin-10 OS=Homo sapiens OX=9606 GN=MYH10 PE=1 SV=3 4.37 1591.1 - 677412 - - - 0.7324 - 1.789 0.292 - 452.2 1 2 0 0.0007 8 0 0 0 8.06E+07 8.63E+07 - - - 2.9518 0.9983 221125_WJC_METTL3_EV_vs_WT_F05.05672.05672.2 0.293 14-Sep K.DAEALSQR.L sp|P35580|MYH10_HUMAN 1 888.4301 0.91 59359 5672 2 888.430246 445.2223 Myosin-10 OS=Homo sapiens OX=9606 GN=MYH10 PE=1 SV=3 4.37 1591.2 - 563778 - - - 0.1531 - 1.523 0.222 - 339.2 1 2 0 0.0001 8 0 0 0 8.06E+07 8.88E+07 - - - 1.9494 0.9904 221125_WJC_METTL3_EV_vs_WT_F05.05674.05674.2 1.08 16-May R.GPPKPGLVR.T "sp|Q8WXI9|P66B_HUMAN,tr|A0A0U1RR30|A0A0U1RR30_HUMAN" 2 919.5603 2.3 59361 5674 2 919.560796 460.7874 Transcriptional repressor p66-beta OS=Homo sapiens OX=9606 GN=GATAD2B PE=1 SV=1 11 1591.5 - 277081 - - - 0.5002 - 1.084 0.194 - 100.5 1 2 0 0.0005 9 0 0 0 2.90E+07 1.26E+07 - - - 0.7071 0.9996 221125_WJC_METTL3_EV_vs_WT_F05.05678.05678.2 0.00695 14-Aug R.DPNNPYDK.N "sp|Q14527|HLTF_HUMAN,tr|A0A0C4DGA6|A0A0C4DGA6_HUMAN" 2 961.4141 2.21 59363 5678 2 961.415162 481.7143 Helicase-like transcription factor OS=Homo sapiens OX=9606 GN=HLTF PE=1 SV=2 4.21 1592 - 1.20E+06 - - - 1.0786 - 1.682 0.409 - 299.7 1 2 0 0.001 8 0 0 0 5.34E+07 2.42E+07 - - - 3.6298 0.9995 221125_WJC_METTL3_EV_vs_WT_F05.05682.05682.2 0.0285 16-Jun K.VLEDSDLK[136.11]K[136.11].S "sp|P11021|BIP_HUMAN,tr|A0A7P0TB36|A0A7P0TB36_HUMAN" 2 1061.5939 0.61 59367 5682 2 1061.59456 531.8042 Endoplasmic reticulum chaperone BiP OS=Homo sapiens OX=9606 GN=HSPA5 PE=1 SV=2 4.56 1592.5 - 270022 - - - 0.584 - 1.559 0.387 - 105.6 1 2 0 0.0006 9 0 0 0 2.85E+07 4.66E+07 - - - 3.1838 0.9994 221125_WJC_METTL3_EV_vs_WT_F05.05686.05686.2 0.00502 14-Jul K.AINNYNPK[136.11].D "sp|Q7Z739|YTHD3_HUMAN,tr|A0A087X0Q1|A0A087X0Q1_HUMAN,tr|A0A024R7W5|A0A024R7W5_HUMAN,tr|A0A087WY31|A0A087WY31_HUMAN" 4 940.4858 1.44 59370 5686 2 940.48652 471.2502 YTH domain-containing family protein 3 OS=Homo sapiens OX=9606 GN=YTHDF3 PE=1 SV=1 8.63 1593 - 3.93E+06 - - - 0.7868 - 1.42 0.399 - 158 1 2 0 0.0007 8 0 0 0 2.14E+08 1.49E+08 - - - 3.0453 0.9997 221125_WJC_METTL3_EV_vs_WT_F05.05687.05687.2 0.000536 16-Sep R.ASYTPSPAR[166.11].S sp|Q96DF8|ESS2_HUMAN 1 958.4748 2.78 59371 5687 2 958.475222 480.2447 Splicing factor ESS-2 homolog OS=Homo sapiens OX=9606 GN=ESS2 PE=1 SV=1 8.79 1593.1 - 1.58E+06 - - - 0.4768 - 1.708 0.442 - 240.7 1 2 0 0.0005 9 0 0 0 3.45E+08 1.24E+08 - - - 3.8542 0.9995 221125_WJC_METTL3_EV_vs_WT_F05.05688.05688.2 0.00129 18-Sep K.LTTASQTNIK.K "sp|Q9UMY1|NOL7_HUMAN,tr|H7C2B1|H7C2B1_HUMAN" 2 1075.5873 0.98 59372 5688 2 1075.589048 538.8009 Nucleolar protein 7 OS=Homo sapiens OX=9606 GN=NOL7 PE=1 SV=2 8.75 1593.2 - 471828 - - - 1.5889 - 1.813 0.41 - 253.6 1 2 0 0.0017 10 0 0 0 7.42E+07 7.57E+07 - - - 3.7295 0.9993 221125_WJC_METTL3_EV_vs_WT_F05.05699.05699.2 0.00153 16-Jul K.EGIPPDQQR.L "sp|P62979|RS27A_HUMAN,sp|P0CG48|UBC_HUMAN,sp|P0CG48|UBC_HUMAN,sp|P0CG48|UBC_HUMAN,sp|P0CG48|UBC_HUMAN,sp|P0CG48|UBC_HUMAN,sp|P0CG48|UBC_HUMAN,sp|P0CG48|UBC_HUMAN,sp|P0CG48|UBC_HUMAN,sp|P0CG48|UBC_HUMAN,sp|P0CG47|UBB_HUMAN,sp|P0CG47|UBB_HUMAN,sp|P0CG47|UBB_HUMAN,sp|P62987|RL40_HUMAN,tr|F5H388|F5H388_HUMAN,tr|F5H388|F5H388_HUMAN,tr|F5GYU3|F5GYU3_HUMAN,tr|F5GYU3|F5GYU3_HUMAN,tr|B4DV12|B4DV12_HUMAN,tr|B4DV12|B4DV12_HUMAN,tr|J3QSA3|J3QSA3_HUMAN,tr|Q5PY61|Q5PY61_HUMAN,tr|Q5PY61|Q5PY61_HUMAN,tr|Q5PY61|Q5PY61_HUMAN,tr|F5H2Z3|F5H2Z3_HUMAN,tr|F5H2Z3|F5H2Z3_HUMAN,tr|M0R2S1|M0R2S1_HUMAN,tr|J3QS39|J3QS39_HUMAN,tr|J3QTR3|J3QTR3_HUMAN,tr|Q96C32|Q96C32_HUMAN,tr|Q96C32|Q96C32_HUMAN,tr|Q96C32|Q96C32_HUMAN,tr|Q96C32|Q96C32_HUMAN,tr|M0R1V7|M0R1V7_HUMAN,tr|F5H747|F5H747_HUMAN,tr|F5H747|F5H747_HUMAN,tr|F5GXK7|F5GXK7_HUMAN,tr|F5GXK7|F5GXK7_HUMAN,tr|M0R1M6|M0R1M6_HUMAN,tr|F5H6Q2|F5H6Q2_HUMAN,tr|F5H6Q2|F5H6Q2_HUMAN,tr|F5GZ39|F5GZ39_HUMAN,tr|J3QKN0|J3QKN0_HUMAN,tr|J3QKN0|J3QKN0_HUMAN,tr|J3QKN0|J3QKN0_HUMAN,tr|F5H265|F5H265_HUMAN,tr|F5H265|F5H265_HUMAN,tr|A0A2R8Y422|A0A2R8Y422_HUMAN" 48 1038.5094 0.63 59380 5699 2 1038.508941 520.262 Ubiquitin-40S ribosomal protein S27a OS=Homo sapiens OX=9606 GN=RPS27A PE=1 SV=2 4.37 1594.5 - 1.03E+06 - - - -0.4641 - 1.47 0.352 - 152 1 2 0 -0.0005 9 0 0 0 6.08E+07 9.58E+07 - - - 2.7553 0.9972 221125_WJC_METTL3_EV_vs_WT_F05.05703.05703.2 0.176 16-Sep K.TIAPQNAPR.D "sp|Q9NYF8|BCLF1_HUMAN,tr|H0YF00|H0YF00_HUMAN,tr|E9PKI6|E9PKI6_HUMAN,tr|A0A1W2PQ43|A0A1W2PQ43_HUMAN,tr|E9PK91|E9PK91_HUMAN,tr|E9PJA7|E9PJA7_HUMAN,tr|E9PK09|E9PK09_HUMAN,tr|E9PQN2|E9PQN2_HUMAN" 8 966.5247 2.28 59381 5703 2 966.524627 484.2696 Bcl-2-associated transcription factor 1 OS=Homo sapiens OX=9606 GN=BCLAF1 PE=1 SV=2 9.41 1595.1 - 2.03E+06 - - - -0.0538 - 1.413 0.202 - 182.2 1 2 0 -0.0001 9 0 0 0 3.99E+10 1.75E+10 - - - 1.5331 0.9936 221125_WJC_METTL3_EV_vs_WT_F05.05704.05704.2 0.195 16-Aug R.LQGEIAHVK.K sp|P35908|K22E_HUMAN 1 993.5607 451.89 59382 5704 2 993.564073 497.7876 "Keratin, type II cytoskeletal 2 epidermal OS=Homo sapiens OX=9606 GN=KRT2 PE=1 SV=2" 6.75 1595.2 - 1.07E+06 - - - 3.3647 - 1.459 0.294 - 163 1 2 0 0.0033 9 0 0 0 2.43E+09 5.37E+06 - - - 2.3043 0.8481 221125_WJC_METTL3_EV_vs_WT_F05.05709.05709.2 0.445 12-Jun L.EIANAHR.K "sp|P10809|CH60_HUMAN,tr|A0A7I2V2X6|A0A7I2V2X6_HUMAN,tr|A0A7I2YQK6|A0A7I2YQK6_HUMAN,tr|A0A7I2V599|A0A7I2V599_HUMAN,tr|A0A7I2YQ71|A0A7I2YQ71_HUMAN,tr|A0A7I2V5M1|A0A7I2V5M1_HUMAN,tr|A0A7I2V5K3|A0A7I2V5K3_HUMAN,tr|A0A7I2V369|A0A7I2V369_HUMAN" 8 809.4144 1.28 59385 5709 2 809.41364 405.7145 "60 kDa heat shock protein, mitochondrial OS=Homo sapiens OX=9606 GN=HSPD1 PE=1 SV=2" 6.85 1595.9 - 582830 - - - -0.939 - 1.227 0.259 - 187.4 1 1 0 -0.0008 7 0 0 0 7.06E+07 5.51E+07 - - - 1.6019 0.9514 221125_WJC_METTL3_EV_vs_WT_F05.05715.05715.2 0.0291 12-Jun L.EIANAHR[166.11].K "sp|P10809|CH60_HUMAN,tr|A0A7I2V2X6|A0A7I2V2X6_HUMAN,tr|A0A7I2YQK6|A0A7I2YQK6_HUMAN,tr|A0A7I2V599|A0A7I2V599_HUMAN,tr|A0A7I2YQ71|A0A7I2YQ71_HUMAN,tr|A0A7I2V5M1|A0A7I2V5M1_HUMAN,tr|A0A7I2V5K3|A0A7I2V5K3_HUMAN,tr|A0A7I2V369|A0A7I2V369_HUMAN" 8 819.4227 1.27 59389 5715 2 819.422024 410.7186 "60 kDa heat shock protein, mitochondrial OS=Homo sapiens OX=9606 GN=HSPD1 PE=1 SV=2" 6.85 1596.5 - 949361 - - - -0.7884 - 1.37 0.348 - 185.5 1 1 0 -0.0006 7 0 0 0 7.23E+07 5.70E+07 - - - 2.6086 0.9993 221125_WJC_METTL3_EV_vs_WT_F05.05719.05719.2 0.0197 18-Aug K.LTTASQTNIK[136.11].K "sp|Q9UMY1|NOL7_HUMAN,tr|H7C2B1|H7C2B1_HUMAN" 2 1083.6015 0.98 59391 5719 2 1083.600485 542.808 Nucleolar protein 7 OS=Homo sapiens OX=9606 GN=NOL7 PE=1 SV=2 8.75 1597 - 1.54E+06 - - - -0.9727 - 1.836 0.29 - 184 1 2 0 -0.0011 10 0 0 0 7.42E+07 7.57E+07 - - - 2.8786 0.995 221125_WJC_METTL3_EV_vs_WT_F05.05726.05726.2 0.065 16-Jun R.GSTWGSGGR.L sp|Q8N1N4|K2C78_HUMAN 1 863.3886 9.53 59395 5726 2 863.387594 432.7016 "Keratin, type II cytoskeletal 78 OS=Homo sapiens OX=9606 GN=KRT78 PE=1 SV=2" 9.75 1597.9 - 1.01E+06 - - - -1.1409 - 1.019 0.295 - 123.2 1 2 0 -0.001 9 0 0 0 8.14E+07 8.55E+06 - - - 1.274 0.9867 221125_WJC_METTL3_EV_vs_WT_F05.05728.05728.2 0.019 16-Aug K.IEVNNATAR.V "sp|O43251|RFOX2_HUMAN,sp|Q9NWB1|RFOX1_HUMAN,sp|A6NFN3|RFOX3_HUMAN,tr|A0A6Q8PGE0|A0A6Q8PGE0_HUMAN,tr|A0A6Q8PH77|A0A6Q8PH77_HUMAN,tr|A0A286YEU2|A0A286YEU2_HUMAN,tr|A0A087X2B1|A0A087X2B1_HUMAN,tr|F8VR27|F8VR27_HUMAN,tr|B7Z1U7|B7Z1U7_HUMAN,tr|B0QYV1|B0QYV1_HUMAN,tr|A0A6Q8PHA3|A0A6Q8PHA3_HUMAN,tr|A0A3B3ITL7|A0A3B3ITL7_HUMAN,tr|F8VZY7|F8VZY7_HUMAN,tr|B0QYY4|B0QYY4_HUMAN,tr|J3KNW3|J3KNW3_HUMAN,tr|F8VZG9|F8VZG9_HUMAN,tr|J3QRF4|J3QRF4_HUMAN,tr|F8VRS4|F8VRS4_HUMAN,tr|A0A6Q8PFM4|A0A6Q8PFM4_HUMAN,tr|S4R469|S4R469_HUMAN,tr|A0A804HKG7|A0A804HKG7_HUMAN,tr|A0A0G2JRD1|A0A0G2JRD1_HUMAN,tr|A0A0G2JRA5|A0A0G2JRA5_HUMAN,tr|A0A804HJM2|A0A804HJM2_HUMAN,tr|I3L1D4|I3L1D4_HUMAN,tr|S4R3K7|S4R3K7_HUMAN" 26 986.5145 1.23 59397 5728 2 986.510926 494.2645 RNA binding protein fox-1 homolog 2 OS=Homo sapiens OX=9606 GN=RBFOX2 PE=1 SV=3 6 1598.1 - 847127 - - - -3.631 - 1.58 0.199 - 141.1 1 2 0 -0.0036 9 0 0 0 1.88E+08 1.53E+08 - - - 1.833 0.9799 221125_WJC_METTL3_EV_vs_WT_F05.05736.05736.2 0.672 14-Aug R.QEEEEVVR[166.11].K sp|Q9BYJ9|YTHD1_HUMAN 1 1026.4857 2.1 59399 5736 2 1026.481093 514.2501 YTH domain-containing family protein 1 OS=Homo sapiens OX=9606 GN=YTHDF1 PE=1 SV=1 4.09 1599.2 - 650305 - - - -4.5115 - 1.625 0.205 - 381.1 1 2 0 -0.0046 8 0 0 0 3.73E+07 1.77E+07 - - - 2.0179 0.997 221125_WJC_METTL3_EV_vs_WT_F05.05743.05743.2 0.00364 14-Aug K.C[160.03]STPEEIK.K "sp|P60981|DEST_HUMAN,tr|F6RFD5|F6RFD5_HUMAN" 2 962.4379 1.56 59401 5743 2 962.44151 482.2262 Destrin OS=Homo sapiens OX=9606 GN=DSTN PE=1 SV=3 4.53 1600.3 - 1.36E+06 - - - 3.754 - 1.629 0.382 - 152.2 1 2 0 0.0036 8 0 0 0 8.04E+07 5.16E+07 - - - 3.333 0.9977 221125_WJC_METTL3_EV_vs_WT_F05.05746.05746.2 0.00308 18-Oct K.TQAASVEAVK[136.11].M "sp|P49005|DPOD2_HUMAN,tr|H7C1B3|H7C1B3_HUMAN,tr|A0A087WWF6|A0A087WWF6_HUMAN,tr|F8W8R3|F8W8R3_HUMAN,tr|C9JHC7|C9JHC7_HUMAN" 5 1010.5488 0.36 59404 5746 2 1010.552471 506.2817 DNA polymerase delta subunit 2 OS=Homo sapiens OX=9606 GN=POLD2 PE=1 SV=1 5.66 1600.6 - 672854 - - - 3.6574 - 1.791 0.391 - 355.6 1 2 0 0.0037 10 0 0 0 7.59E+06 2.08E+07 - - - 3.5545 0.9989 221125_WJC_METTL3_EV_vs_WT_F05.05749.05749.2 0.198 14-Aug R.QTSLVSSR[166.11].R "sp|Q13573|SNW1_HUMAN,tr|G3V3A4|G3V3A4_HUMAN,tr|G3V5R3|G3V5R3_HUMAN" 3 886.4748 1.13 59405 5749 2 886.473756 444.2447 SNW domain-containing protein 1 OS=Homo sapiens OX=9606 GN=SNW1 PE=1 SV=1 9.75 1601 - 1.98E+06 - - - -1.1382 - 1.74 0.244 - 294 1 2 0 -0.001 8 0 0 0 2.17E+08 1.93E+08 - - - 2.5134 0.9997 221125_WJC_METTL3_EV_vs_WT_F05.05750.05750.2 0.000405 18-Oct R.NIC[160.03]GENASVK[136.11].V "sp|O00443|P3C2A_HUMAN,tr|A0A0C4DGF9|A0A0C4DGF9_HUMAN" 2 1098.5219 2.98 59406 5750 2 1098.521837 550.2682 Phosphatidylinositol 4-phosphate 3-kinase C2 domain-containing subunit alpha OS=Homo sapiens OX=9606 GN=PIK3C2A PE=1 SV=2 5.99 1601.2 - 787950 - - - -0.0646 - 1.673 0.419 - 253.3 1 2 0 -0.0001 10 0 0 0 4.95E+07 1.66E+07 - - - 3.5722 0.9998 221125_WJC_METTL3_EV_vs_WT_F05.05753.05753.2 2.26E-06 18-Oct K.ETEGDVTSVK.D sp|P50990|TCPQ_HUMAN 1 1063.5033 0.41 59407 5753 2 1063.501659 532.7589 T-complex protein 1 subunit theta OS=Homo sapiens OX=9606 GN=CCT8 PE=1 SV=4 4.14 1601.6 - 1.10E+06 - - - -1.575 - 1.975 0.563 - 444.9 1 2 0 -0.0017 10 0 0 0 1.01E+09 2.45E+09 - - - 5.0985 0.9893 221125_WJC_METTL3_EV_vs_WT_F05.05755.05755.2 0.111 20-Jul R.LNAR[166.11]PGVGGVR[166.11].S "sp|Q9BY77|PDIP3_HUMAN,tr|F6VRR5|F6VRR5_HUMAN,tr|F8WCX5|F8WCX5_HUMAN,tr|Q6R954|Q6R954_HUMAN,tr|Q8WUT1|Q8WUT1_HUMAN,tr|F8WEE2|F8WEE2_HUMAN" 6 1114.6474 1.53 59408 5755 2 1114.651212 558.331 Polymerase delta-interacting protein 3 OS=Homo sapiens OX=9606 GN=POLDIP3 PE=1 SV=2 12 1601.8 - 420928 - - - 3.4065 - 1.446 0.27 - 66.3 2 2 0 0.0038 11 0 0 0 5.45E+08 3.56E+08 - - - 1.8973 0.9956 221125_WJC_METTL3_EV_vs_WT_F05.05760.05760.2 0.17 14-Jul K.AINNYNPK.D "sp|Q7Z739|YTHD3_HUMAN,tr|A0A087X0Q1|A0A087X0Q1_HUMAN,tr|A0A024R7W5|A0A024R7W5_HUMAN,tr|A0A087WY31|A0A087WY31_HUMAN" 4 932.4716 1.43 59410 5760 2 932.470137 467.2431 YTH domain-containing family protein 3 OS=Homo sapiens OX=9606 GN=YTHDF3 PE=1 SV=1 8.63 1602.4 - 2.28E+06 - - - -1.5475 - 1.278 0.239 - 125.2 1 2 0 -0.0014 8 0 0 0 2.14E+08 1.49E+08 - - - 1.5456 0.7985 221125_WJC_METTL3_EV_vs_WT_F05.05761.05761.2 0.119 18-Jul L.NARPGVGGVR.S "sp|Q9BY77|PDIP3_HUMAN,tr|F6VRR5|F6VRR5_HUMAN,tr|F8WCX5|F8WCX5_HUMAN,tr|Q6R954|Q6R954_HUMAN,tr|Q8WUT1|Q8WUT1_HUMAN,tr|F8WEE2|F8WEE2_HUMAN" 6 981.5468 1.59 59411 5761 2 981.54704 491.7807 Polymerase delta-interacting protein 3 OS=Homo sapiens OX=9606 GN=POLDIP3 PE=1 SV=2 12 1602.5 - 653448 - - - 0.2333 - 1.345 0.187 - 79.3 1 1 0 0.0002 10 0 0 0 4.46E+08 2.81E+08 - - - 1.2494 0.8379 221125_WJC_METTL3_EV_vs_WT_F05.05768.05768.2 1.09 14-Jun K.AINVQEEK[136.11].L "sp|Q13813|SPTN1_HUMAN,tr|A0A0D9SF54|A0A0D9SF54_HUMAN,tr|A0A0D9SGF6|A0A0D9SGF6_HUMAN" 3 937.496 3.58 59414 5768 2 937.492616 469.7553 "Spectrin alpha chain, non-erythrocytic 1 OS=Homo sapiens OX=9606 GN=SPTAN1 PE=1 SV=3" 4.53 1603.4 - 1.17E+06 - - - -3.6213 - 1.363 0.036 - 102 4 2 0 -0.0034 8 0 0 0 1.38E+08 3.86E+07 - - - -0.0291 0.9999 221125_WJC_METTL3_EV_vs_WT_F05.05769.05769.2 3.33E-06 18-Nov R.QGGESETFAK.R "sp|Q13485|SMAD4_HUMAN,tr|K7EIU8|K7EIU8_HUMAN,tr|K7EL18|K7EL18_HUMAN,tr|K7ENG1|K7ENG1_HUMAN,tr|K7EL15|K7EL15_HUMAN,tr|K7EIJ2|K7EIJ2_HUMAN,tr|K7ES96|K7ES96_HUMAN" 7 1052.4775 1.15 59415 5769 2 1052.477124 527.246 Mothers against decapentaplegic homolog 4 OS=Homo sapiens OX=9606 GN=SMAD4 PE=1 SV=1 4.53 1603.6 - 858691 - - - -0.3135 - 2.204 0.506 - 364.5 1 2 0 -0.0003 10 0 0 0 3.51E+07 3.04E+07 - - - 4.9841 0.9986 221125_WJC_METTL3_EV_vs_WT_F05.05770.05770.2 0.164 14-Aug K.AINVQEEK.L "sp|Q13813|SPTN1_HUMAN,tr|A0A0D9SF54|A0A0D9SF54_HUMAN,tr|A0A0D9SGF6|A0A0D9SGF6_HUMAN" 3 929.4818 2.39 59416 5770 2 929.480597 465.7482 "Spectrin alpha chain, non-erythrocytic 1 OS=Homo sapiens OX=9606 GN=SPTAN1 PE=1 SV=3" 4.53 1603.6 - 1.71E+06 - - - -1.3061 - 1.776 0.212 - 200.3 1 2 0 -0.0012 8 0 0 0 9.17E+07 3.83E+07 - - - 2.3387 0.9991 221125_WJC_METTL3_EV_vs_WT_F05.05772.05772.2 0.0408 20-Oct R.LNARPGVGGVR.S "sp|Q9BY77|PDIP3_HUMAN,tr|F6VRR5|F6VRR5_HUMAN,tr|F8WCX5|F8WCX5_HUMAN,tr|Q6R954|Q6R954_HUMAN,tr|Q8WUT1|Q8WUT1_HUMAN,tr|F8WEE2|F8WEE2_HUMAN" 6 1094.6309 1.53 59418 5772 2 1094.629586 548.3227 Polymerase delta-interacting protein 3 OS=Homo sapiens OX=9606 GN=POLDIP3 PE=1 SV=2 12 1603.9 - 749245 - - - -1.1776 - 1.829 0.28 - 118.2 1 2 0 -0.0013 11 0 0 0 5.45E+08 3.56E+08 - - - 2.742 0.9987 221125_WJC_METTL3_EV_vs_WT_F05.05777.05777.2 0.0069 16-Jun R.C[160.03]C[160.03]PDTC[160.03]GIK.C sp|P03973|SLPI_HUMAN 1 1109.4304 999 59421 5777 2 1109.427595 555.7225 Antileukoproteinase OS=Homo sapiens OX=9606 GN=SLPI PE=1 SV=2 5.82 1604.6 - 256626 - - - -2.5157 - 1.122 0.52 - 97.8 1 2 0 -0.0028 9 0 0 0 4.39E+07 0.00E+00 - - - 3.2139 0.7857 221125_WJC_METTL3_EV_vs_WT_F05.05782.05782.2 0.0399 14-Jun L.QGEIAHVK.K sp|P35908|K22E_HUMAN 1 880.4767 260.03 59424 5782 2 880.475361 441.2456 "Keratin, type II cytoskeletal 2 epidermal OS=Homo sapiens OX=9606 GN=KRT2 PE=1 SV=2" 6.75 1605.2 - 1.04E+07 - - - -1.4822 - 1.216 0.252 - 145.8 1 1 0 -0.0013 8 0 0 0 6.65E+08 2.56E+06 - - - 1.4917 0.9594 221125_WJC_METTL3_EV_vs_WT_F05.05783.05783.2 0.0142 14-Aug R.GDPVNVSR.V "sp|P22735|TGM1_HUMAN,tr|H0YLT9|H0YLT9_HUMAN" 2 842.4246 1.76 59425 5783 2 842.422135 422.2196 Protein-glutamine gamma-glutamyltransferase K OS=Homo sapiens OX=9606 GN=TGM1 PE=1 SV=4 5.84 1605.3 - 2.23E+06 - - - -2.9617 - 1.366 0.09 - 259.9 1 2 0 -0.0025 8 0 0 0 1.05E+08 6.00E+07 - - - 0.6456 0.9983 221125_WJC_METTL3_EV_vs_WT_F05.05787.05787.2 0.0244 14-Jun R.DSYGGPPR[166.11].R "sp|Q96E39|RMXL1_HUMAN,sp|P38159|RBMX_HUMAN,tr|H3BUY5|H3BUY5_HUMAN,tr|H3BT71|H3BT71_HUMAN,tr|H0Y6E7|H0Y6E7_HUMAN" 5 857.3907 1.59 59427 5787 2 857.389706 429.7026 "RNA binding motif protein, X-linked-like-1 OS=Homo sapiens OX=9606 GN=RBMXL1 PE=1 SV=1" 5.84 1605.8 - 4.02E+06 - - - -1.1605 - 1.365 0.294 - 116.2 1 2 0 -0.001 8 0 0 0 7.74E+08 4.86E+08 - - - 2.1506 0.9706 221125_WJC_METTL3_EV_vs_WT_F05.05796.05796.2 0.376 14-Jul K.ISTVVSSK.E "sp|P37108|SRP14_HUMAN,tr|H0YLA2|H0YLA2_HUMAN" 2 819.4702 0.85 59434 5796 2 819.468217 410.7424 Signal recognition particle 14 kDa protein OS=Homo sapiens OX=9606 GN=SRP14 PE=1 SV=2 8.75 1606.9 - 609583 - - - -2.3991 - 1.187 0.14 - 90.5 1 2 0 -0.002 8 0 0 0 1.52E+07 1.79E+07 - - - 0.5914 0.9978 221125_WJC_METTL3_EV_vs_WT_F05.05800.05800.2 0.0238 16-Oct K.MQAVQEATR.L sp|Q15149|PLEC_HUMAN 1 1032.5022 6.69 59436 5800 2 1032.498396 517.2584 Plectin OS=Homo sapiens OX=9606 GN=PLEC PE=1 SV=3 5.75 1607.4 - 863105 - - - -3.7123 - 2.066 0.337 - 409.8 1 2 0 -0.0038 9 0 0 0 5.89E+07 8.79E+06 - - - 3.6281 0.9397 221125_WJC_METTL3_EV_vs_WT_F05.05802.05802.2 0.405 18-Aug R.AVAPPTPASK.R sp|Q14781|CBX2_HUMAN 1 937.5233 2.24 59437 5802 2 937.528078 469.7689 Chromobox protein homolog 2 OS=Homo sapiens OX=9606 GN=CBX2 PE=1 SV=2 8.8 1607.7 - 841672 - - - 5.1156 - 1.581 0.158 - 185.9 1 2 0 0.0048 10 0 0 0 6.72E+07 3.00E+07 - - - 1.4851 0.9585 221125_WJC_METTL3_EV_vs_WT_F05.05805.05805.2 5.79 16-Jul R.LQANQSLNR.M sp|Q13472|TOP3A_HUMAN 1 1042.552 2.19 59439 5805 2 1042.550934 522.2833 DNA topoisomerase 3-alpha OS=Homo sapiens OX=9606 GN=TOP3A PE=1 SV=1 9.75 1608 - 605400 - - - -0.9803 - 1.319 0.022 - 107.3 3 2 0 -0.001 9 0 0 0 3.43E+07 1.57E+07 - - - -0.2089 0.9852 221125_WJC_METTL3_EV_vs_WT_F05.05813.05813.2 0.16 14-Aug K.QVQEEISR.M "sp|Q9BVL2|NUP58_HUMAN,tr|H7BYF2|H7BYF2_HUMAN,tr|Q5JRG1|Q5JRG1_HUMAN" 3 987.4985 2.49 59442 5813 2 987.49553 494.7565 Nucleoporin p58\p45 OS=Homo sapiens OX=9606 GN=NUP58 PE=1 SV=1 4.53 1609 - 4.17E+06 - - - -3.0309 - 1.448 0.17 - 330.6 1 2 0 -0.003 8 0 0 0 1.96E+08 7.88E+07 - - - 1.4121 0.9996 221125_WJC_METTL3_EV_vs_WT_F05.05821.05821.2 0.0642 16-Aug K.GEELSC[160.03]EER.N sp|P31947|1433S_HUMAN 1 1107.4503 999 59445 5821 2 1107.4493 554.7324 14-3-3 protein sigma OS=Homo sapiens OX=9606 GN=SFN PE=1 SV=1 4.09 1610.1 - 443257 - - - -0.8605 - 1.865 0.359 - 343.2 1 2 0 -0.001 9 0 0 0 3.96E+07 0.00E+00 - - - 3.4954 0.9952 221125_WJC_METTL3_EV_vs_WT_F05.05824.05824.2 0.0809 14-Jun K.ENEVEEVK.E sp|Q8NC51|PAIRB_HUMAN 1 974.4557 1.12 59447 5824 2 974.457788 488.2351 Plasminogen activator inhibitor 1 RNA-binding protein OS=Homo sapiens OX=9606 GN=SERBP1 PE=1 SV=2 4.09 1610.4 - 1.48E+06 - - - 2.1879 - 1.305 0.272 - 199.5 1 2 0 0.0021 8 0 0 0 7.64E+07 6.85E+07 - - - 1.8522 0.9965 221125_WJC_METTL3_EV_vs_WT_F05.05827.05827.2 0.375 12-Aug K.NQEVTIK.A "sp|Q13948|CASP_HUMAN,sp|P39880|CUX1_HUMAN,tr|A0A2R8Y8D0|A0A2R8Y8D0_HUMAN,tr|A0A2R8Y852|A0A2R8Y852_HUMAN,tr|A0A2R8YDI1|A0A2R8YDI1_HUMAN" 5 830.4498 1.3 59448 5827 2 830.44857 416.2322 Protein CASP OS=Homo sapiens OX=9606 GN=CUX1 PE=1 SV=2 6 1610.8 - 6.77E+06 - - - -1.4595 - 1.589 0.158 - 418.8 1 2 0 -0.0012 7 0 0 0 3.45E+08 2.65E+08 - - - 1.675 0.9937 221125_WJC_METTL3_EV_vs_WT_F05.05834.05834.2 0.259 14-Jun R.HVFGQPVK[136.11].N "sp|Q9BR76|COR1B_HUMAN,tr|A0A087WW53|A0A087WW53_HUMAN,tr|F5H0D2|F5H0D2_HUMAN,tr|F5H390|F5H390_HUMAN" 4 918.5167 0.45 59451 5834 2 918.514966 460.2656 Coronin-1B OS=Homo sapiens OX=9606 GN=CORO1B PE=1 SV=1 8.76 1611.7 - 231313 - - - -1.8737 - 1.217 0.244 - 131.3 1 2 0 -0.0017 8 0 0 0 4.92E+06 1.08E+07 - - - 1.4349 0.7625 221125_WJC_METTL3_EV_vs_WT_F05.05835.05835.2 0.19 16-Aug N.ARPGVGGVR.S "sp|Q9BY77|PDIP3_HUMAN,tr|F6VRR5|F6VRR5_HUMAN,tr|F8WCX5|F8WCX5_HUMAN,tr|Q6R954|Q6R954_HUMAN,tr|Q8WUT1|Q8WUT1_HUMAN,tr|F8WEE2|F8WEE2_HUMAN" 6 867.5039 1.71 59452 5835 2 867.502168 434.7592 Polymerase delta-interacting protein 3 OS=Homo sapiens OX=9606 GN=POLDIP3 PE=1 SV=2 12 1611.9 - 1.84E+06 - - - -1.9781 - 1.421 0.214 - 116.3 1 1 0 -0.0017 9 0 0 0 1.16E+08 6.78E+07 - - - 1.6376 0.9997 221125_WJC_METTL3_EV_vs_WT_F05.05840.05840.2 1.58E-05 22-Oct K.LEAADEGSGDVK.Y "sp|Q02218|ODO1_HUMAN,sp|Q9ULD0|OGDHL_HUMAN,tr|E9PFG7|E9PFG7_HUMAN,tr|E9PDF2|E9PDF2_HUMAN,tr|A0A0D9SFS3|A0A0D9SFS3_HUMAN,tr|E9PCR7|E9PCR7_HUMAN" 6 1189.5463 1.74 59454 5840 2 1189.544805 595.7804 "2-oxoglutarate dehydrogenase, mitochondrial OS=Homo sapiens OX=9606 GN=OGDH PE=1 SV=3" 3.92 1612.6 - 283383 - - - -1.2248 - 2.224 0.387 - 286.4 1 2 0 -0.0015 12 0 0 0 9.27E+06 5.33E+06 - - - 4.002 0.9997 221125_WJC_METTL3_EV_vs_WT_F05.05843.05843.2 0.00217 14-Aug K.EHC[160.03]LVGVK[136.11].G sp|Q86U44|MTA70_HUMAN 1 948.4942 0.03 59455 5843 2 948.493558 475.2544 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 6.83 1612.9 - 2.57E+07 - - - -0.7159 - 1.542 0.455 - 230 1 2 0 -0.0007 8 0 0 0 3.04E+09 1.21E+11 - - - 3.7076 0.9971 221125_WJC_METTL3_EV_vs_WT_F05.05845.05845.2 0.0853 14-Oct R.RVEELVAK.R sp|Q9NWB6|ARGL1_HUMAN 1 942.5498 0.7 59457 5845 2 942.550892 472.2822 Arginine and glutamate-rich protein 1 OS=Homo sapiens OX=9606 GN=ARGLU1 PE=1 SV=1 6.14 1613.2 - 1.01E+06 - - - 1.1257 - 1.734 0.146 - 428.6 1 2 0 0.0011 8 0 0 0 5.69E+07 8.11E+07 - - - 1.7791 0.9509 221125_WJC_METTL3_EV_vs_WT_F05.05855.05855.2 2.1 12-Jul K.NQEVTIK[136.11].A "sp|Q13948|CASP_HUMAN,sp|P39880|CUX1_HUMAN,tr|A0A2R8Y8D0|A0A2R8Y8D0_HUMAN,tr|A0A2R8Y852|A0A2R8Y852_HUMAN,tr|A0A2R8YDI1|A0A2R8YDI1_HUMAN" 5 838.464 1.3 59460 5855 2 838.461443 420.2393 Protein CASP OS=Homo sapiens OX=9606 GN=CUX1 PE=1 SV=2 6 1614.5 - 5.87E+06 - - - -3.0282 - 1.334 0.08 - 259.9 1 2 0 -0.0025 7 0 0 0 3.45E+08 2.66E+08 - - - 0.5442 0.9994 221125_WJC_METTL3_EV_vs_WT_F05.05857.05857.2 0.00313 16-Jul K.EGIPPDQQR[166.11].L "sp|P62979|RS27A_HUMAN,sp|P0CG48|UBC_HUMAN,sp|P0CG48|UBC_HUMAN,sp|P0CG48|UBC_HUMAN,sp|P0CG48|UBC_HUMAN,sp|P0CG48|UBC_HUMAN,sp|P0CG48|UBC_HUMAN,sp|P0CG48|UBC_HUMAN,sp|P0CG48|UBC_HUMAN,sp|P0CG48|UBC_HUMAN,sp|P0CG47|UBB_HUMAN,sp|P0CG47|UBB_HUMAN,sp|P0CG47|UBB_HUMAN,sp|P62987|RL40_HUMAN,tr|F5H388|F5H388_HUMAN,tr|F5H388|F5H388_HUMAN,tr|F5GYU3|F5GYU3_HUMAN,tr|F5GYU3|F5GYU3_HUMAN,tr|B4DV12|B4DV12_HUMAN,tr|B4DV12|B4DV12_HUMAN,tr|J3QSA3|J3QSA3_HUMAN,tr|Q5PY61|Q5PY61_HUMAN,tr|Q5PY61|Q5PY61_HUMAN,tr|Q5PY61|Q5PY61_HUMAN,tr|F5H2Z3|F5H2Z3_HUMAN,tr|F5H2Z3|F5H2Z3_HUMAN,tr|M0R2S1|M0R2S1_HUMAN,tr|J3QS39|J3QS39_HUMAN,tr|J3QTR3|J3QTR3_HUMAN,tr|Q96C32|Q96C32_HUMAN,tr|Q96C32|Q96C32_HUMAN,tr|Q96C32|Q96C32_HUMAN,tr|Q96C32|Q96C32_HUMAN,tr|M0R1V7|M0R1V7_HUMAN,tr|F5H747|F5H747_HUMAN,tr|F5H747|F5H747_HUMAN,tr|F5GXK7|F5GXK7_HUMAN,tr|F5GXK7|F5GXK7_HUMAN,tr|M0R1M6|M0R1M6_HUMAN,tr|F5H6Q2|F5H6Q2_HUMAN,tr|F5H6Q2|F5H6Q2_HUMAN,tr|F5GZ39|F5GZ39_HUMAN,tr|J3QKN0|J3QKN0_HUMAN,tr|J3QKN0|J3QKN0_HUMAN,tr|J3QKN0|J3QKN0_HUMAN,tr|F5H265|F5H265_HUMAN,tr|F5H265|F5H265_HUMAN,tr|A0A2R8Y422|A0A2R8Y422_HUMAN" 48 1048.5177 0.75 59462 5857 2 1048.518254 525.2661 Ubiquitin-40S ribosomal protein S27a OS=Homo sapiens OX=9606 GN=RPS27A PE=1 SV=2 4.37 1614.7 - 2.04E+06 - - - 0.535 - 1.454 0.392 - 156.9 1 2 0 0.0006 9 0 0 0 1.62E+08 2.17E+08 - - - 3.0191 0.9985 221125_WJC_METTL3_EV_vs_WT_F05.05861.05861.2 0.00246 16-Sep R.TTTESEVMK.Y "sp|P11586|C1TC_HUMAN,tr|F5H2F4|F5H2F4_HUMAN,tr|V9GYY3|V9GYY3_HUMAN" 3 1024.4747 1.35 59463 5861 2 1024.477609 513.2446 "C-1-tetrahydrofolate synthase, cytoplasmic OS=Homo sapiens OX=9606 GN=MTHFD1 PE=1 SV=4" 4.53 1615.3 - 1.90E+06 - - - 2.862 - 1.86 0.342 - 314.4 1 2 0 0.0029 9 0 0 0 1.01E+08 7.49E+07 - - - 3.3615 0.9993 221125_WJC_METTL3_EV_vs_WT_F05.05863.05863.2 0.0195 16-Aug R.QFTSSSSMK.G "sp|P02533|K1C14_HUMAN,sp|P08779|K1C16_HUMAN,tr|K7ENV3|K7ENV3_HUMAN" 3 1001.4488 168.49 59464 5863 2 1001.447225 501.7317 "Keratin, type I cytoskeletal 14 OS=Homo sapiens OX=9606 GN=KRT14 PE=1 SV=4" 8.75 1615.5 - 1.60E+07 - - - -1.5687 - 1.698 0.357 - 250.3 1 2 0 -0.0016 9 0 0 0 5.65E+09 3.35E+07 - - - 3.209 0.9956 221125_WJC_METTL3_EV_vs_WT_F05.05864.05864.2 0.0264 14-Jul K.VLALSQHK[136.11].F "sp|Q8TB72|PUM2_HUMAN,tr|A0A0C4DG68|A0A0C4DG68_HUMAN" 2 902.5429 1.21 59465 5864 2 902.542242 452.2787 Pumilio homolog 2 OS=Homo sapiens OX=9606 GN=PUM2 PE=1 SV=2 8.73 1615.6 - 1.33E+06 - - - -0.7302 - 1.32 0.186 - 214.4 1 2 0 -0.0007 8 0 0 0 1.24E+08 1.03E+08 - - - 1.2519 0.9997 221125_WJC_METTL3_EV_vs_WT_F05.05872.05872.2 0.000504 18-Aug R.EMQENDASMR[166.11].D sp|P31930|QCR1_HUMAN 1 1219.4837 3.02 59468 5872 2 1219.482008 610.7491 "Cytochrome b-c1 complex subunit 1, mitochondrial OS=Homo sapiens OX=9606 GN=UQCRC1 PE=1 SV=3" 4.14 1616.6 - 246279 - - - -1.3809 - 1.509 0.497 - 306.5 1 2 0 -0.0017 10 0 0 0 1.23E+07 4.06E+06 - - - 3.8598 0.9758 221125_WJC_METTL3_EV_vs_WT_F05.05874.05874.2 0.0133 12-Jul K.YEDEINK.R "sp|P48668|K2C6C_HUMAN,sp|P05787|K2C8_HUMAN,sp|Q01546|K22O_HUMAN,sp|Q7Z794|K2C1B_HUMAN,sp|P12035|K2C3_HUMAN,sp|P04264|K2C1_HUMAN,sp|P04259|K2C6B_HUMAN,sp|P13647|K2C5_HUMAN,sp|P35908|K22E_HUMAN,sp|O95678|K2C75_HUMAN,sp|Q5XKE5|K2C79_HUMAN,sp|P02538|K2C6A_HUMAN,tr|F8VUG2|F8VUG2_HUMAN,tr|F8W0C6|F8W0C6_HUMAN,tr|F8VP67|F8VP67_HUMAN,tr|F8W1U3|F8W1U3_HUMAN,tr|H0YIN9|H0YIN9_HUMAN" 17 909.408 1073.84 59469 5874 2 909.403052 455.7113 "Keratin, type II cytoskeletal 6C OS=Homo sapiens OX=9606 GN=KRT6C PE=1 SV=3" 4.14 1616.8 - 1.07E+06 - - - -5.4156 - 1.281 0.35 - 144.6 1 2 0 -0.0049 7 0 0 0 6.95E+08 6.47E+05 - - - 2.4092 0.9989 221125_WJC_METTL3_EV_vs_WT_F05.05883.05883.2 0.00654 18-May R.EMQENDASMR.D sp|P31930|QCR1_HUMAN 1 1209.4754 3.02 59474 5883 2 1209.476789 605.745 "Cytochrome b-c1 complex subunit 1, mitochondrial OS=Homo sapiens OX=9606 GN=UQCRC1 PE=1 SV=3" 4.14 1617.8 - 362795 - - - 1.1302 - 1.354 0.367 - 109.8 1 2 0 0.0014 10 0 0 0 1.23E+07 4.06E+06 - - - 2.5972 0.9992 221125_WJC_METTL3_EV_vs_WT_F05.05888.05888.2 0.000143 18-Oct K.ETEGDVTSVK[136.11].D sp|P50990|TCPQ_HUMAN 1 1071.5175 0.41 59476 5888 2 1071.51557 536.766 T-complex protein 1 subunit theta OS=Homo sapiens OX=9606 GN=CCT8 PE=1 SV=4 4.14 1618.4 - 2.36E+06 - - - -1.8329 - 1.656 0.381 - 298.3 1 2 0 -0.002 10 0 0 0 1.01E+09 2.45E+09 - - - 3.2624 0.9997 221125_WJC_METTL3_EV_vs_WT_F05.05897.05897.2 0.0368 16-Oct R.EESTTGFDK.S "sp|Q9Y2W1|TR150_HUMAN,tr|A0A3B3ITZ9|A0A3B3ITZ9_HUMAN" 2 1012.4349 3.15 59478 5897 2 1012.433844 507.2247 Thyroid hormone receptor-associated protein 3 OS=Homo sapiens OX=9606 GN=THRAP3 PE=1 SV=2 4.14 1619.7 - 2.43E+06 - - - -1.0628 - 1.875 0.386 - 591.2 1 2 0 -0.0011 9 0 0 0 2.07E+09 6.56E+08 - - - 3.7103 0.9994 221125_WJC_METTL3_EV_vs_WT_F05.05915.05915.2 0.000405 14-Jul K.EATFSNPK[136.11].T "sp|O75534|CSDE1_HUMAN,tr|E9PLT0|E9PLT0_HUMAN" 2 900.4432 0.66 59483 5915 2 900.442806 451.2289 Cold shock domain-containing protein E1 OS=Homo sapiens OX=9606 GN=CSDE1 PE=1 SV=2 6.1 1622.2 - 2.07E+06 - - - -0.4898 - 1.269 0.43 - 196.2 1 2 0 -0.0004 8 0 0 0 1.46E+08 2.20E+08 - - - 2.9353 0.9979 221125_WJC_METTL3_EV_vs_WT_F05.05919.05919.2 0.000277 16-Dec R.ILQEHEQIK.K sp|Q14152|EIF3A_HUMAN 1 1136.619 1.76 59484 5919 2 1136.616804 569.3168 Eukaryotic translation initiation factor 3 subunit A OS=Homo sapiens OX=9606 GN=EIF3A PE=1 SV=1 5.4 1622.7 - 1.70E+06 - - - -1.9083 - 1.761 0.222 - 428.4 1 2 0 -0.0022 9 0 0 0 7.82E+07 4.44E+07 - - - 2.3171 0.9936 221125_WJC_METTL3_EV_vs_WT_F05.05925.05925.2 0.00625 14-Jul R.SINNYNPK[136.11].D sp|Q9Y5A9|YTHD2_HUMAN 1 956.4807 0.47 59486 5925 2 956.476778 479.2476 YTH domain-containing family protein 2 OS=Homo sapiens OX=9606 GN=YTHDF2 PE=1 SV=2 8.31 1623.5 - 1.38E+07 - - - -4.0952 - 1.514 0.337 - 149.8 1 2 0 -0.0039 8 0 0 0 9.11E+08 1.95E+09 - - - 2.7797 0.9997 221125_WJC_METTL3_EV_vs_WT_F05.05932.05932.2 0.00778 16-Sep K.ALTTPTHYK.L "sp|P52948|NUP98_HUMAN,tr|A0A3B3ITD8|A0A3B3ITD8_HUMAN,tr|H0YEN4|H0YEN4_HUMAN,tr|H0YCR0|H0YCR0_HUMAN" 4 1030.5447 2.77 59488 5932 2 1030.54523 516.2796 Nuclear pore complex protein Nup98-Nup96 OS=Homo sapiens OX=9606 GN=NUP98 PE=1 SV=4 8.64 1624.4 - 2.27E+06 - - - 0.4706 - 1.938 0.388 - 289.7 1 2 0 0.0005 9 0 0 0 3.86E+08 1.39E+08 - - - 3.8208 0.9832 221125_WJC_METTL3_EV_vs_WT_F05.05942.05942.2 0.112 12-Jun K.MYEEHLK[136.11].R "sp|P84090|ERH_HUMAN,tr|G3V279|G3V279_HUMAN" 2 956.4517 0.001 59493 5942 2 956.447676 479.2331 Enhancer of rudimentary homolog OS=Homo sapiens OX=9606 GN=ERH PE=1 SV=1 5.38 1625.8 - 1.18E+07 - - - -4.2104 - 1.181 0.328 - 125.4 1 2 0 -0.004 7 0 0 0 0.00E+00 3.74E+08 - - - 1.9895 0.9948 221125_WJC_METTL3_EV_vs_WT_F05.05954.05954.2 1.65 14-Aug R.ANGVEINR.E sp|O94906|PRP6_HUMAN 1 871.4512 3.09 59499 5954 2 871.449196 436.7329 Pre-mRNA-processing factor 6 OS=Homo sapiens OX=9606 GN=PRPF6 PE=1 SV=1 6.05 1627.3 - 2.15E+06 - - - -2.2755 - 1.787 0.137 - 391.4 1 2 0 -0.002 8 0 0 0 2.28E+08 7.39E+07 - - - 1.8031 1 221125_WJC_METTL3_EV_vs_WT_F05.05955.05955.2 0.000805 17/26 K.K[136.11]GPGEVAGTVTGQK[136.11].R "sp|Q86U44|MTA70_HUMAN,tr|F5H6D8|F5H6D8_HUMAN,tr|H0YFV6|H0YFV6_HUMAN,tr|B4DTN4|B4DTN4_HUMAN" 4 1343.738 0.001 59500 5955 2 1343.733397 672.8763 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 8.59 1627.4 - 781068 - - - -3.4099 - 3.396 0.56 - 664.3 1 2 0 -0.0046 14 0 0 0 0.00E+00 1.52E+08 - - - 6.2438 0.827 221125_WJC_METTL3_EV_vs_WT_F05.05958.05958.2 0.502 14-Aug R.ANGVEINR[166.11].E sp|O94906|PRP6_HUMAN 1 881.4594 3.09 59501 5958 2 881.453002 441.737 Pre-mRNA-processing factor 6 OS=Homo sapiens OX=9606 GN=PRPF6 PE=1 SV=1 6.05 1627.8 - 772510 - - - -7.314 - 1.686 0.146 - 266.7 1 2 0 -0.0064 8 0 0 0 2.29E+08 7.41E+07 - - - 1.6927 0.9997 221125_WJC_METTL3_EV_vs_WT_F05.05965.05965.2 0.0116 16-Sep R.QVDQLTNDK[136.11].A "sp|P08670|VIME_HUMAN,tr|B0YJC4|B0YJC4_HUMAN" 2 1067.5339 1.9 59503 5965 2 1067.532488 534.7742 Vimentin OS=Homo sapiens OX=9606 GN=VIM PE=1 SV=4 4.21 1628.8 - 9.07E+06 - - - -1.2786 - 1.814 0.431 - 354 1 2 0 -0.0014 9 0 0 0 8.27E+09 4.36E+09 - - - 3.9469 0.9726 221125_WJC_METTL3_EV_vs_WT_F05.05967.05967.2 8.05 12-Jul R.TLDGFKK.F "sp|P07237|PDIA1_HUMAN,tr|A0A7P0T8C0|A0A7P0T8C0_HUMAN,tr|H7BZ94|H7BZ94_HUMAN,tr|B3KTQ9|B3KTQ9_HUMAN,tr|A0A7P0TA71|A0A7P0TA71_HUMAN,tr|A0A7P0T9K9|A0A7P0T9K9_HUMAN,tr|H0Y3Z3|H0Y3Z3_HUMAN,tr|A0A7P0TA35|A0A7P0TA35_HUMAN,tr|A0A7P0TB26|A0A7P0TB26_HUMAN,tr|A0A7P0T9U6|A0A7P0T9U6_HUMAN,tr|I3L0S0|I3L0S0_HUMAN,tr|I3L3P5|I3L3P5_HUMAN,tr|A0A7P0T8J3|A0A7P0T8J3_HUMAN" 13 807.4491 1.51 59504 5967 2 807.448063 404.7318 Protein disulfide-isomerase OS=Homo sapiens OX=9606 GN=P4HB PE=1 SV=3 8.26 1629 - 3.20E+06 - - - -1.2273 - 1.008 0.145 - 145.5 1 2 0 -0.001 7 0 0 0 1.54E+08 1.02E+08 - - - 0.1369 0.9807 221125_WJC_METTL3_EV_vs_WT_F05.05969.05969.2 0.0647 12-Jul R.NNLIQQK[136.11].N "sp|Q9NR56|MBNL1_HUMAN,sp|Q5VZF2|MBNL2_HUMAN,sp|Q9NUK0|MBNL3_HUMAN,tr|H7C4T5|H7C4T5_HUMAN,tr|Q86VM6|Q86VM6_HUMAN,tr|C9J4T8|C9J4T8_HUMAN,tr|A0A0A0MQX8|A0A0A0MQX8_HUMAN,tr|A0A7P0T9I3|A0A7P0T9I3_HUMAN,tr|B1AKI6|B1AKI6_HUMAN,tr|C9JP00|C9JP00_HUMAN,tr|O95205|O95205_HUMAN" 11 864.4909 1.56 59505 5969 2 864.487545 433.2527 Muscleblind-like protein 1 OS=Homo sapiens OX=9606 GN=MBNL1 PE=1 SV=2 8.75 1629.2 - 1.42E+06 - - - -3.8416 - 1.33 0.232 - 223.1 1 2 0 -0.0033 7 0 0 0 1.69E+09 1.09E+09 - - - 1.6571 0.944 221125_WJC_METTL3_EV_vs_WT_F05.05983.05983.2 0.0922 20-Sep R.NPPPNSDPNLR.R sp|Q96I24|FUBP3_HUMAN 1 1219.5945 3.22 59511 5983 2 1219.588727 610.8046 Far upstream element-binding protein 3 OS=Homo sapiens OX=9606 GN=FUBP3 PE=1 SV=2 5.84 1631 - 633874 - - - -4.7737 - 1.229 0.236 - 129.1 1 2 0 -0.0058 11 0 0 0 6.87E+07 2.13E+07 - - - 1.3401 0.8468 221125_WJC_METTL3_EV_vs_WT_F05.05985.05985.2 0.784 12-Jun R.TLDGFK[136.11]K[136.11].F "sp|P07237|PDIA1_HUMAN,tr|A0A7P0T8C0|A0A7P0T8C0_HUMAN,tr|H7BZ94|H7BZ94_HUMAN,tr|B3KTQ9|B3KTQ9_HUMAN,tr|A0A7P0TA71|A0A7P0TA71_HUMAN,tr|A0A7P0T9K9|A0A7P0T9K9_HUMAN,tr|H0Y3Z3|H0Y3Z3_HUMAN,tr|A0A7P0TA35|A0A7P0TA35_HUMAN,tr|A0A7P0TB26|A0A7P0TB26_HUMAN,tr|A0A7P0T9U6|A0A7P0T9U6_HUMAN,tr|I3L0S0|I3L0S0_HUMAN,tr|I3L3P5|I3L3P5_HUMAN,tr|A0A7P0T8J3|A0A7P0T8J3_HUMAN" 13 823.4775 1.51 59513 5985 2 823.473804 412.746 Protein disulfide-isomerase OS=Homo sapiens OX=9606 GN=P4HB PE=1 SV=3 8.26 1631.2 - 2.92E+06 - - - -4.4324 - 1.006 0.181 - 128 1 2 0 -0.0037 7 0 0 0 1.54E+08 1.02E+08 - - - 0.3957 0.9985 221125_WJC_METTL3_EV_vs_WT_F05.05989.05989.2 0.0208 14-Aug R.STSYGYSR.S sp|Q13242|SRSF9_HUMAN 1 919.4036 1.01 59515 5989 2 919.402555 460.7091 Serine\arginine-rich splicing factor 9 OS=Homo sapiens OX=9606 GN=SRSF9 PE=1 SV=1 8.31 1631.6 - 2.35E+06 - - - -1.0931 - 1.578 0.241 - 411.3 1 2 0 -0.001 8 0 0 0 7.84E+07 7.75E+07 - - - 2.1965 0.9976 221125_WJC_METTL3_EV_vs_WT_F05.05994.05994.2 0.104 12-Jul R.NNLIQQK.N "sp|Q9NR56|MBNL1_HUMAN,sp|Q5VZF2|MBNL2_HUMAN,sp|Q9NUK0|MBNL3_HUMAN,tr|H7C4T5|H7C4T5_HUMAN,tr|Q86VM6|Q86VM6_HUMAN,tr|C9J4T8|C9J4T8_HUMAN,tr|A0A0A0MQX8|A0A0A0MQX8_HUMAN,tr|A0A7P0T9I3|A0A7P0T9I3_HUMAN,tr|B1AKI6|B1AKI6_HUMAN,tr|C9JP00|C9JP00_HUMAN,tr|O95205|O95205_HUMAN" 11 856.4767 1.56 59516 5994 2 856.476459 429.2456 Muscleblind-like protein 1 OS=Homo sapiens OX=9606 GN=MBNL1 PE=1 SV=2 8.75 1632.4 - 1.03E+07 - - - -0.2417 - 1.306 0.237 - 243 1 2 0 -0.0002 7 0 0 0 1.70E+09 1.09E+09 - - - 1.6373 0.976 221125_WJC_METTL3_EV_vs_WT_F05.06003.06003.2 8.93E-05 16-Oct K.GC[160.03]EVVVSGK[136.11].L "sp|P23396|RS3_HUMAN,tr|H0YEU2|H0YEU2_HUMAN,tr|E9PSF4|E9PSF4_HUMAN,tr|E9PL09|E9PL09_HUMAN,tr|E9PJN9|E9PJN9_HUMAN" 5 941.4732 0.47 59519 6003 2 941.476988 471.7439 40S ribosomal protein S3 OS=Homo sapiens OX=9606 GN=RPS3 PE=1 SV=2 5.99 1633.6 - 1.71E+07 - - - 4.0585 - 1.769 0.127 - 477 1 2 0 0.0038 9 0 0 0 5.06E+08 1.07E+09 - - - 1.6281 0.9529 221125_WJC_METTL3_EV_vs_WT_F05.06004.06004.2 2.01 14-May K.ELQNEVEK[136.11].Q "sp|Q86U42|PABP2_HUMAN,tr|B4DEH8|B4DEH8_HUMAN,tr|G3V4T2|G3V4T2_HUMAN,tr|A0A7I2V383|A0A7I2V383_HUMAN" 4 995.5015 1.21 59520 6004 2 995.5002 498.758 Polyadenylate-binding protein 2 OS=Homo sapiens OX=9606 GN=PABPN1 PE=1 SV=3 4.25 1633.8 - 944377 - - - -1.2958 - 1.144 0.127 - 82.3 20 2 0 -0.0013 8 0 0 0 1.88E+08 1.55E+08 - - - -0.1968 0.9995 221125_WJC_METTL3_EV_vs_WT_F05.06008.06008.2 0.0196 12-Jul K.QQC[160.03]AFDR.K "sp|Q5HYJ3|FA76B_HUMAN,sp|Q8TAV0|FA76A_HUMAN,tr|F5GX09|F5GX09_HUMAN,tr|E9PQL1|E9PQL1_HUMAN" 4 923.3919 1.11 59522 6008 2 923.393347 462.7033 Protein FAM76B OS=Homo sapiens OX=9606 GN=FAM76B PE=1 SV=3 5.83 1634.2 - 1.16E+06 - - - 1.5129 - 1.504 0.459 - 307.7 1 2 0 0.0014 7 0 0 0 3.13E+07 2.82E+07 - - - 3.7239 0.9906 221125_WJC_METTL3_EV_vs_WT_F05.06016.06016.2 0.00121 22-Sep K.APAASK[136.11]APAAPK[136.11].V sp|Q9P2P1|NYNRI_HUMAN 1 1094.6419 1.35 59526 6016 2 1094.639866 548.3282 Protein NYNRIN OS=Homo sapiens OX=9606 GN=NYNRIN PE=2 SV=3 10 1635.2 - 662764 - - - -1.8527 - 1.703 0.369 - 291.9 1 2 1 -0.002 12 0 0 0 4.77E+07 3.55E+07 - - - 3.1666 0.9933 221125_WJC_METTL3_EV_vs_WT_F05.06018.06018.2 2.63E-05 13/22 K.PATLTTTSATSK[136.11].L "sp|O43670|ZN207_HUMAN,tr|J3QRS9|J3QRS9_HUMAN,tr|X6R4W8|X6R4W8_HUMAN,tr|J3KS31|J3KS31_HUMAN" 4 1185.6332 0.26 59527 6018 2 1185.6329 593.8239 BUB3-interacting and GLEBS motif-containing protein ZNF207 OS=Homo sapiens OX=9606 GN=ZNF207 PE=1 SV=1 9.18 1635.5 - 850011 - - - -0.2809 - 2.48 0.481 - 589.1 1 1 0 -0.0003 12 0 0 0 1.02E+07 3.90E+07 - - - 4.9833 0.9643 221125_WJC_METTL3_EV_vs_WT_F05.06020.06020.2 0.806 14-Jul K.HTGYVGLK[136.11].N "sp|Q93009|UBP7_HUMAN,tr|A0A669KBL1|A0A669KBL1_HUMAN,tr|F5H2X1|F5H2X1_HUMAN,tr|H3BND8|H3BND8_HUMAN" 4 881.4851 1.24 59529 6020 2 881.487722 441.7498 Ubiquitin carboxyl-terminal hydrolase 7 OS=Homo sapiens OX=9606 GN=USP7 PE=1 SV=2 8.6 1635.7 - 1.48E+06 - - - 3.029 - 1.311 0.126 - 119.6 1 2 0 0.0027 8 0 0 0 1.10E+08 8.88E+07 - - - 0.7875 0.9971 221125_WJC_METTL3_EV_vs_WT_F05.06022.06022.2 0.0525 16-Aug K.TIAPQNAPR[166.11].D "sp|Q9NYF8|BCLF1_HUMAN,tr|H0YF00|H0YF00_HUMAN,tr|E9PKI6|E9PKI6_HUMAN,tr|A0A1W2PQ43|A0A1W2PQ43_HUMAN,tr|E9PK91|E9PK91_HUMAN,tr|E9PJA7|E9PJA7_HUMAN,tr|E9PK09|E9PK09_HUMAN,tr|E9PQN2|E9PQN2_HUMAN" 8 976.5329 2.81 59531 6022 2 976.532139 489.2738 Bcl-2-associated transcription factor 1 OS=Homo sapiens OX=9606 GN=BCLAF1 PE=1 SV=2 9.41 1635.9 - 268251 - - - -0.8295 - 1.371 0.223 - 219.3 1 2 0 -0.0008 9 0 0 0 7.11E+07 2.53E+07 - - - 1.6007 0.9955 221125_WJC_METTL3_EV_vs_WT_F05.06024.06024.2 0.0939 12-Jul R.GQQQVFK.G "sp|P40939|ECHA_HUMAN,tr|A0A2R8YG21|A0A2R8YG21_HUMAN,tr|H0YFD6|H0YFD6_HUMAN,tr|A0A2R8Y4F5|A0A2R8Y4F5_HUMAN" 4 833.4396 1.1 59532 6024 2 833.437786 417.7271 "Trifunctional enzyme subunit alpha, mitochondrial OS=Homo sapiens OX=9606 GN=HADHA PE=1 SV=2" 8.75 1636.2 - 2.40E+06 - - - -2.1189 - 1.493 0.204 - 320.8 1 2 0 -0.0018 7 0 0 0 1.11E+08 1.01E+08 - - - 1.8171 0.9987 221125_WJC_METTL3_EV_vs_WT_F05.06026.06026.2 0.0176 12-Jul K.AEC[160.03]WSQK[136.11].M "sp|Q8IZH2|XRN1_HUMAN,tr|H7C5E4|H7C5E4_HUMAN,tr|H7C583|H7C583_HUMAN" 3 915.4 1.21 59533 6026 2 915.399386 458.7073 5'-3' exoribonuclease 1 OS=Homo sapiens OX=9606 GN=XRN1 PE=1 SV=1 6.04 1636.4 - 1.21E+06 - - - -0.6729 - 1.277 0.326 - 270.1 1 2 0 -0.0006 7 0 0 0 5.07E+07 4.19E+07 - - - 2.2234 0.9946 221125_WJC_METTL3_EV_vs_WT_F05.06031.06031.2 0.0664 12-Jun K.AEC[160.03]WSQK.M "sp|Q8IZH2|XRN1_HUMAN,tr|H7C5E4|H7C5E4_HUMAN,tr|H7C583|H7C583_HUMAN" 3 907.3858 1.21 59535 6031 2 907.383953 454.7002 5'-3' exoribonuclease 1 OS=Homo sapiens OX=9606 GN=XRN1 PE=1 SV=1 6.04 1637 - 1.85E+06 - - - -2.0377 - 1.106 0.308 - 161.7 1 2 0 -0.0018 7 0 0 0 5.07E+07 4.19E+07 - - - 1.6345 1 221125_WJC_METTL3_EV_vs_WT_F05.06033.06033.3 1.23E-07 14/52 K.K[136.11]GPGEVAGTVTGQK[136.11].R "sp|Q86U44|MTA70_HUMAN,tr|F5H6D8|F5H6D8_HUMAN,tr|H0YFV6|H0YFV6_HUMAN,tr|B4DTN4|B4DTN4_HUMAN" 4 1343.738 0 59537 6033 3 1343.73588 448.9199 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 8.59 1637.2 - 7.98E+06 - - - -1.5621 - 2.721 0.526 - 227.5 1 2 0 -0.0021 14 0 0 0 5.44E+05 6.39E+08 - - - 7.064 0.9956 221125_WJC_METTL3_EV_vs_WT_F05.06039.06039.2 0.0695 14-Jul K.VQEQELTR.L sp|P15924|DESP_HUMAN 1 1001.5142 18.93 59539 6039 2 1001.512894 501.7644 Desmoplakin OS=Homo sapiens OX=9606 GN=DSP PE=1 SV=3 4.53 1638 - 3.04E+06 - - - -1.2781 - 1.557 0.143 - 213.6 1 2 0 -0.0013 8 0 0 0 1.36E+08 7.16E+06 - - - 1.4321 0.9987 221125_WJC_METTL3_EV_vs_WT_F05.06045.06045.2 0.4 20-Aug R.NPPPNSDPNLR[166.11].R sp|Q96I24|FUBP3_HUMAN 1 1229.6028 3.22 59542 6045 2 1229.600718 615.8087 Far upstream element-binding protein 3 OS=Homo sapiens OX=9606 GN=FUBP3 PE=1 SV=2 5.84 1638.8 - 322477 - - - -1.7087 - 1.767 0.276 - 182.7 1 2 0 -0.0021 11 0 0 0 6.87E+07 2.13E+07 - - - 2.6189 0.9986 221125_WJC_METTL3_EV_vs_WT_F05.06048.06048.2 0.182 14-Jul K.ELQNEVEK.Q "sp|Q86U42|PABP2_HUMAN,tr|B4DEH8|B4DEH8_HUMAN,tr|G3V4T2|G3V4T2_HUMAN,tr|A0A7I2V383|A0A7I2V383_HUMAN" 4 987.4873 1.08 59544 6048 2 987.485785 494.7509 Polyadenylate-binding protein 2 OS=Homo sapiens OX=9606 GN=PABPN1 PE=1 SV=3 4.25 1639.2 - 5.77E+06 - - - -1.5241 - 1.464 0.308 - 220.1 1 2 0 -0.0015 8 0 0 0 1.67E+08 1.55E+08 - - - 2.465 0.9425 221125_WJC_METTL3_EV_vs_WT_F05.06051.06051.2 0.00319 14-Jul R.LEDYQANR.K "sp|P52948|NUP98_HUMAN,tr|A0A3B3ITD8|A0A3B3ITD8_HUMAN" 2 1007.4672 2.33 59546 6051 2 1007.463526 504.7409 Nuclear pore complex protein Nup98-Nup96 OS=Homo sapiens OX=9606 GN=NUP98 PE=1 SV=4 4.37 1639.5 - 412352 - - - -3.6696 - 1.622 0.034 - 165.9 1 2 0 -0.0037 8 0 0 0 5.77E+07 2.48E+07 - - - 0.7497 0.9983 221125_WJC_METTL3_EV_vs_WT_F05.06052.06052.2 0.00236 12-Aug K.SDSFAPK[136.11].T "sp|Q9Y2W1|TR150_HUMAN,tr|A0A3B3ITZ9|A0A3B3ITZ9_HUMAN" 2 758.369 0.001 59547 6052 2 758.3684 380.1918 Thyroid hormone receptor-associated protein 3 OS=Homo sapiens OX=9606 GN=THRAP3 PE=1 SV=2 5.55 1639.6 - 4.25E+06 - - - -0.8162 - 1.478 0.237 - 344.1 1 2 0 -0.0006 7 0 0 0 0.00E+00 1.51E+08 - - - 2.0292 0.9701 221125_WJC_METTL3_EV_vs_WT_F05.06055.06055.2 0.0953 18-Oct G.AC[160.03]GVGGYGSR.S "sp|P13647|K2C5_HUMAN,tr|F8VV57|F8VV57_HUMAN" 2 982.4291 4.11 59548 6055 2 982.427763 492.2218 "Keratin, type II cytoskeletal 5 OS=Homo sapiens OX=9606 GN=KRT5 PE=1 SV=3" 8.27 1639.9 - 1.41E+06 - - - -1.3243 - 1.785 0.365 - 446 1 1 0 -0.0013 10 0 0 0 4.24E+07 1.03E+07 - - - 3.3538 0.9994 221125_WJC_METTL3_EV_vs_WT_F05.06060.06060.2 0.00442 14-Sep K.HPLTQELK.E sp|P82932|RT06_HUMAN 1 964.5342 0.68 59551 6060 2 964.535087 483.2744 "28S ribosomal protein S6, mitochondrial OS=Homo sapiens OX=9606 GN=MRPS6 PE=1 SV=3" 6.75 1640.6 - 759257 - - - 0.9393 - 1.497 0.388 - 229.8 1 2 0 0.0009 8 0 0 0 4.56E+07 6.69E+07 - - - 3.1233 0.9975 221125_WJC_METTL3_EV_vs_WT_F05.06062.06062.2 0.326 16-Sep R.IQQIAEGEK[136.11].V "sp|Q14254|FLOT2_HUMAN,tr|E7EMK3|E7EMK3_HUMAN,tr|K7EKW9|K7EKW9_HUMAN,tr|J3QLD9|J3QLD9_HUMAN" 4 1022.5488 1.41 59552 6062 2 1022.548688 512.2817 Flotillin-2 OS=Homo sapiens OX=9606 GN=FLOT2 PE=1 SV=2 4.53 1640.8 - 2.19E+06 - - - -0.0851 - 1.662 0.148 - 237.5 1 2 0 -0.0001 9 0 0 0 8.82E+07 6.26E+07 - - - 1.6038 0.9974 221125_WJC_METTL3_EV_vs_WT_F05.06066.06066.2 0.00158 18-Nov K.QAALEEEQAR[166.11].L "sp|Q13492|PICAL_HUMAN,tr|H0YEF7|H0YEF7_HUMAN,tr|H0YCY1|H0YCY1_HUMAN,tr|H0YEH1|H0YEH1_HUMAN" 4 1153.5603 1.95 59556 6066 2 1153.556066 577.7874 Phosphatidylinositol-binding clathrin assembly protein OS=Homo sapiens OX=9606 GN=PICALM PE=1 SV=2 4.25 1641.3 - 267298 - - - -3.6582 - 1.974 0.33 - 556.1 1 2 0 -0.0042 10 0 0 0 5.20E+07 2.67E+07 - - - 3.3753 0.9984 221125_WJC_METTL3_EV_vs_WT_F05.06069.06069.2 0.146 16-Aug K.TGPTVTQVK.A "sp|Q13428|TCOF_HUMAN,tr|E7ETY2|E7ETY2_HUMAN,tr|H0Y8Y7|H0Y8Y7_HUMAN,tr|A0A3B3IS06|A0A3B3IS06_HUMAN,tr|A0A6I8PRA0|A0A6I8PRA0_HUMAN" 5 929.5182 0.91 59557 6069 2 929.517255 465.7664 Treacle protein OS=Homo sapiens OX=9606 GN=TCOF1 PE=1 SV=3 8.41 1641.7 - 2.11E+06 - - - -1.0124 - 1.539 0.248 - 207.9 1 2 0 -0.0009 9 0 0 0 5.36E+07 5.92E+07 - - - 2.1197 0.999 221125_WJC_METTL3_EV_vs_WT_F05.06070.06070.2 0.00805 14-Jul R.ADDYEQVK.N "sp|P61421|VA0D1_HUMAN,tr|J3QL14|J3QL14_HUMAN,tr|F5GYQ1|F5GYQ1_HUMAN,tr|R4GN72|R4GN72_HUMAN" 4 966.4294 1.38 59558 6070 2 966.429206 484.222 V-type proton ATPase subunit d 1 OS=Homo sapiens OX=9606 GN=ATP6V0D1 PE=1 SV=1 4.03 1641.8 - 1.13E+06 - - - -0.2432 - 1.268 0.358 - 158 1 2 0 -0.0002 8 0 0 0 2.83E+07 2.05E+07 - - - 2.4012 0.9966 221125_WJC_METTL3_EV_vs_WT_F05.06071.06071.2 0.401 18-Jul K.LIQESDQHLK.D "sp|O14776|TCRG1_HUMAN,tr|A0A7P0T8N8|A0A7P0T8N8_HUMAN" 2 1209.6354 0.61 59559 6071 2 1209.635285 605.825 Transcription elongation regulator 1 OS=Homo sapiens OX=9606 GN=TCERG1 PE=1 SV=2 5.32 1641.9 - 146613 - - - -0.0546 - 1.362 0.2 - 125.2 1 2 0 -0.0001 10 0 0 0 2.19E+06 3.56E+06 - - - 1.3806 0.9998 221125_WJC_METTL3_EV_vs_WT_F05.06076.06076.2 0.00144 18-Oct K.QAALEEEQAR.L "sp|Q13492|PICAL_HUMAN,tr|H0YEF7|H0YEF7_HUMAN,tr|H0YCY1|H0YCY1_HUMAN,tr|H0YEH1|H0YEH1_HUMAN" 4 1143.552 1.95 59562 6076 2 1143.552452 572.7833 Phosphatidylinositol-binding clathrin assembly protein OS=Homo sapiens OX=9606 GN=PICALM PE=1 SV=2 4.25 1642.5 - 1.20E+06 - - - 0.3813 - 2.267 0.395 - 468.7 1 2 0 0.0004 10 0 0 0 5.20E+07 2.67E+07 - - - 4.2429 0.999 221125_WJC_METTL3_EV_vs_WT_F05.06077.06077.2 0.0052 18-Oct R.AAAMANNLQK.G "sp|Q14498|RBM39_HUMAN,tr|H0Y4X3|H0Y4X3_HUMAN,tr|A0A0U1RQH7|A0A0U1RQH7_HUMAN,tr|G3XAC6|G3XAC6_HUMAN" 4 1030.523 0.73 59563 6077 2 1030.523185 516.2688 RNA-binding protein 39 OS=Homo sapiens OX=9606 GN=RBM39 PE=1 SV=2 8.8 1642.6 - 925453 - - - 0.2145 - 2.007 0.187 - 440.4 1 2 0 0.0002 10 0 0 0 3.70E+07 5.08E+07 - - - 2.3666 0.9998 221125_WJC_METTL3_EV_vs_WT_F05.06081.06081.2 0.00182 18-Aug K.ISEC[160.03]ASVETK[136.11].Q "sp|Q9BYP7|WNK3_HUMAN,tr|A0A087WYK2|A0A087WYK2_HUMAN" 2 1130.5369 45.72 59565 6081 2 1130.537177 566.2757 Serine\threonine-protein kinase WNK3 OS=Homo sapiens OX=9606 GN=WNK3 PE=1 SV=3 4.53 1643.1 - 387809 - - - 0.2539 - 1.837 0.427 - 147.6 1 2 0 0.0003 10 0 0 0 4.92E+08 1.08E+07 - - - 3.8922 0.9989 221125_WJC_METTL3_EV_vs_WT_F05.06083.06083.2 0.000212 22-Oct R.FGGSGSQVDSAR.M sp|Q13200|PSMD2_HUMAN 1 1166.5316 0.56 59567 6083 2 1166.536024 584.2731 26S proteasome non-ATPase regulatory subunit 2 OS=Homo sapiens OX=9606 GN=PSMD2 PE=1 SV=3 5.84 1643.4 - 314538 - - - 3.7796 - 2.204 0.487 - 238 1 2 0 0.0044 12 0 0 0 1.25E+07 2.24E+07 - - - 4.7159 0.9997 221125_WJC_METTL3_EV_vs_WT_F05.06085.06085.2 0.00196 14-Sep K.EHC[160.03]LVGVK[136.11].G sp|Q86U44|MTA70_HUMAN 1 948.4942 0.03 59568 6085 2 948.494469 475.2544 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 6.83 1643.6 - 4.94E+07 - - - 0.2446 - 1.558 0.465 - 404.4 1 2 0 0.0002 8 0 0 0 3.04E+09 1.21E+11 - - - 3.8127 0.9977 221125_WJC_METTL3_EV_vs_WT_F05.06089.06089.2 0.0325 16-Jul R.IQQIAEGEK.V "sp|Q14254|FLOT2_HUMAN,tr|E7EMK3|E7EMK3_HUMAN,tr|K7EKW9|K7EKW9_HUMAN,tr|J3QLD9|J3QLD9_HUMAN" 4 1014.5346 1.4 59571 6089 2 1014.535385 508.2746 Flotillin-2 OS=Homo sapiens OX=9606 GN=FLOT2 PE=1 SV=2 4.53 1644 - 2.52E+06 - - - 0.7984 - 1.352 0.258 - 127.4 1 2 0 0.0008 9 0 0 0 8.82E+07 6.32E+07 - - - 1.8188 0.9998 221125_WJC_METTL3_EV_vs_WT_F05.06093.06093.2 0.0928 18-Dec K.STNVTVAAAR.G "sp|Q5BKZ1|ZN326_HUMAN,tr|A0A0A0MRN4|A0A0A0MRN4_HUMAN" 2 988.5302 1.27 59573 6093 2 988.531068 495.2724 DBIRD complex subunit ZNF326 OS=Homo sapiens OX=9606 GN=ZNF326 PE=1 SV=2 9.47 1644.5 - 2.16E+06 - - - 0.9206 - 2.465 0.425 - 639.6 1 2 0 0.0009 10 0 0 0 6.01E+07 4.73E+07 - - - 4.6981 0.9992 221125_WJC_METTL3_EV_vs_WT_F05.06097.06097.2 0.00727 16-Jul K.EGIPPDQQR[166.11].L "sp|P62979|RS27A_HUMAN,sp|P0CG48|UBC_HUMAN,sp|P0CG48|UBC_HUMAN,sp|P0CG48|UBC_HUMAN,sp|P0CG48|UBC_HUMAN,sp|P0CG48|UBC_HUMAN,sp|P0CG48|UBC_HUMAN,sp|P0CG48|UBC_HUMAN,sp|P0CG48|UBC_HUMAN,sp|P0CG48|UBC_HUMAN,sp|P0CG47|UBB_HUMAN,sp|P0CG47|UBB_HUMAN,sp|P0CG47|UBB_HUMAN,sp|P62987|RL40_HUMAN,tr|F5H388|F5H388_HUMAN,tr|F5H388|F5H388_HUMAN,tr|F5GYU3|F5GYU3_HUMAN,tr|F5GYU3|F5GYU3_HUMAN,tr|B4DV12|B4DV12_HUMAN,tr|B4DV12|B4DV12_HUMAN,tr|J3QSA3|J3QSA3_HUMAN,tr|Q5PY61|Q5PY61_HUMAN,tr|Q5PY61|Q5PY61_HUMAN,tr|Q5PY61|Q5PY61_HUMAN,tr|F5H2Z3|F5H2Z3_HUMAN,tr|F5H2Z3|F5H2Z3_HUMAN,tr|M0R2S1|M0R2S1_HUMAN,tr|J3QS39|J3QS39_HUMAN,tr|J3QTR3|J3QTR3_HUMAN,tr|Q96C32|Q96C32_HUMAN,tr|Q96C32|Q96C32_HUMAN,tr|Q96C32|Q96C32_HUMAN,tr|Q96C32|Q96C32_HUMAN,tr|M0R1V7|M0R1V7_HUMAN,tr|F5H747|F5H747_HUMAN,tr|F5H747|F5H747_HUMAN,tr|F5GXK7|F5GXK7_HUMAN,tr|F5GXK7|F5GXK7_HUMAN,tr|M0R1M6|M0R1M6_HUMAN,tr|F5H6Q2|F5H6Q2_HUMAN,tr|F5H6Q2|F5H6Q2_HUMAN,tr|F5GZ39|F5GZ39_HUMAN,tr|J3QKN0|J3QKN0_HUMAN,tr|J3QKN0|J3QKN0_HUMAN,tr|J3QKN0|J3QKN0_HUMAN,tr|F5H265|F5H265_HUMAN,tr|F5H265|F5H265_HUMAN,tr|A0A2R8Y422|A0A2R8Y422_HUMAN" 48 1048.5177 0.62 59576 6097 2 1048.518836 525.2661 Ubiquitin-40S ribosomal protein S27a OS=Homo sapiens OX=9606 GN=RPS27A PE=1 SV=2 4.37 1645 - 1.66E+06 - - - 1.0901 - 1.551 0.343 - 171.9 1 2 0 0.0011 9 0 0 0 1.14E+08 1.82E+08 - - - 2.8438 0.972 221125_WJC_METTL3_EV_vs_WT_F05.06108.06108.2 0.0872 14-Jul K.EDALPGQK[136.11].T "sp|P35613|BASI_HUMAN,tr|A0A7P0TA85|A0A7P0TA85_HUMAN,tr|A0A7P0TB04|A0A7P0TB04_HUMAN,tr|A0A2R8YDZ0|A0A2R8YDZ0_HUMAN,tr|I3L192|I3L192_HUMAN" 5 864.4432 1.36 59584 6108 2 864.444048 433.2289 Basigin OS=Homo sapiens OX=9606 GN=BSG PE=1 SV=2 4.37 1646.4 - 758107 - - - 0.9266 - 1.299 0.036 - 153.2 1 2 0 0.0008 8 0 0 0 8.43E+07 6.18E+07 - - - 0.0956 0.9993 221125_WJC_METTL3_EV_vs_WT_F05.06109.06109.2 0.0198 14-Aug R.QGEAEFNR[166.11].L "sp|O43707|ACTN4_HUMAN,tr|F5GXS2|F5GXS2_HUMAN" 2 959.4336 1.42 59585 6109 2 959.434604 480.7241 Alpha-actinin-4 OS=Homo sapiens OX=9606 GN=ACTN4 PE=1 SV=2 4.53 1646.5 - 415997 - - - 1.0162 - 1.658 0.319 - 271.5 1 2 0 0.001 8 0 0 0 2.09E+07 1.47E+07 - - - 2.9217 0.9915 221125_WJC_METTL3_EV_vs_WT_F05.06114.06114.2 0.0118 16-Nov R.LRSEIDNVK.K sp|P04264|K2C1_HUMAN 1 1072.5877 999 59588 6114 2 1072.588613 537.3011 "Keratin, type II cytoskeletal 1 OS=Homo sapiens OX=9606 GN=KRT1 PE=1 SV=6" 6.07 1647.2 - 843127 - - - 0.8764 - 1.864 0.269 - 382.2 1 2 1 0.0009 9 0 0 0 1.57E+09 0.00E+00 - - - 2.8291 0.9968 221125_WJC_METTL3_EV_vs_WT_F05.06115.06115.2 0.0739 14-Aug K.EDALPGQK.T "sp|P35613|BASI_HUMAN,tr|A0A7P0TA85|A0A7P0TA85_HUMAN,tr|A0A7P0TB04|A0A7P0TB04_HUMAN,tr|A0A2R8YDZ0|A0A2R8YDZ0_HUMAN,tr|I3L192|I3L192_HUMAN" 5 856.429 1.36 59589 6115 2 856.430985 429.2218 Basigin OS=Homo sapiens OX=9606 GN=BSG PE=1 SV=2 4.37 1647.2 - 1.23E+06 - - - 2.2629 - 1.553 0.253 - 208.6 1 2 0 0.0019 8 0 0 0 8.43E+07 6.18E+07 - - - 2.2366 0.9578 221125_WJC_METTL3_EV_vs_WT_F05.06116.06116.2 1.06 14-Jul R.AQVEDLQK.A sp|Q96ED9|HOOK2_HUMAN 1 929.4818 89.27 59590 6116 2 929.483795 465.7482 Protein Hook homolog 2 OS=Homo sapiens OX=9606 GN=HOOK2 PE=1 SV=3 4.37 1647.3 - 701923 - - - 2.1345 - 1.343 0.045 - 179.7 1 2 0 0.002 8 0 0 0 7.37E+08 8.25E+06 - - - 0.2622 0.9376 221125_WJC_METTL3_EV_vs_WT_F05.06122.06122.2 0.008 16-Aug Y.GGGLSVSSR.F sp|P08779|K1C16_HUMAN 1 818.4246 8.85 59594 6122 2 818.425677 410.2196 "Keratin, type I cytoskeletal 16 OS=Homo sapiens OX=9606 GN=KRT16 PE=1 SV=4" 9.75 1648.1 - 5.78E+06 - - - 1.2793 - 1.511 0.328 - 229.6 1 1 0 0.001 9 0 0 0 9.90E+07 1.12E+07 - - - 2.6575 0.9972 221125_WJC_METTL3_EV_vs_WT_F05.06123.06123.2 0.912 12-Aug K.R[166.11]YEEIVK[136.11].E "sp|P68104|EF1A1_HUMAN,sp|Q5VTE0|EF1A3_HUMAN,tr|A0A7I2V659|A0A7I2V659_HUMAN,tr|A0A7I2V3H3|A0A7I2V3H3_HUMAN,tr|A0A7I2V5N4|A0A7I2V5N4_HUMAN,tr|A0A087WVQ9|A0A087WVQ9_HUMAN,tr|A0A087WV01|A0A087WV01_HUMAN" 7 953.5301 0.69 59595 6123 2 953.531977 477.7723 Elongation factor 1-alpha 1 OS=Homo sapiens OX=9606 GN=EEF1A1 PE=1 SV=1 6.14 1648.2 - 2.09E+06 - - - 1.9664 - 1.709 0.195 - 402.3 1 2 0 0.0019 7 0 0 0 1.38E+08 2.00E+08 - - - 2.1787 0.9858 221125_WJC_METTL3_EV_vs_WT_F05.06125.06125.2 6.23 12-Jul R.FLEQQNK[136.11].L "sp|P08670|VIME_HUMAN,sp|Q9NSB2|KRT84_HUMAN,sp|P14136|GFAP_HUMAN,sp|Q14533|KRT81_HUMAN,sp|P48668|K2C6C_HUMAN,sp|P05787|K2C8_HUMAN,sp|Q01546|K22O_HUMAN,sp|P19013|K2C4_HUMAN,sp|Q8N1N4|K2C78_HUMAN,sp|P12035|K2C3_HUMAN,sp|P78386|KRT85_HUMAN,sp|P04259|K2C6B_HUMAN,sp|P13647|K2C5_HUMAN,sp|O43790|KRT86_HUMAN,sp|P78385|KRT83_HUMAN,sp|P08729|K2C7_HUMAN,sp|O95678|K2C75_HUMAN,sp|Q5XKE5|K2C79_HUMAN,sp|P02538|K2C6A_HUMAN,tr|A0A1W2PR46|A0A1W2PR46_HUMAN,tr|F8VUG2|F8VUG2_HUMAN,tr|A0A087X106|A0A087X106_HUMAN,tr|A0A1X7SBR3|A0A1X7SBR3_HUMAN,tr|B4DIR1|B4DIR1_HUMAN,tr|K7EJU1|K7EJU1_HUMAN,tr|F8W0C6|F8W0C6_HUMAN,tr|A0A1X7SCE1|A0A1X7SCE1_HUMAN,tr|Q8IWY7|Q8IWY7_HUMAN,tr|U3KPR1|U3KPR1_HUMAN,tr|F8W1U3|F8W1U3_HUMAN,tr|K7EKH9|K7EKH9_HUMAN,tr|B0YJC4|B0YJC4_HUMAN,tr|K7ELP4|K7ELP4_HUMAN,tr|A0A1B0GTT5|A0A1B0GTT5_HUMAN" 34 913.4749 5.32 59597 6125 2 913.476978 457.7447 Vimentin OS=Homo sapiens OX=9606 GN=VIM PE=1 SV=4 6 1648.3 - 1.24E+06 - - - 2.2956 - 1.419 0.127 - 141 1 2 0 0.0021 7 0 0 0 1.14E+09 2.14E+08 - - - 1.0872 0.9978 221125_WJC_METTL3_EV_vs_WT_F05.06126.06126.3 0.0038 Dec-36 K.VYEGER[166.11]PLTK[136.11].D "sp|P11021|BIP_HUMAN,tr|A0A7P0TAI0|A0A7P0TAI0_HUMAN" 2 1208.652 0.6 59598 6126 3 1208.654285 403.8913 Endoplasmic reticulum chaperone BiP OS=Homo sapiens OX=9606 GN=HSPA5 PE=1 SV=2 6.11 1648.4 - 725402 - - - 1.8839 - 1.844 0.254 - 152 1 2 0 0.0023 10 0 0 0 6.91E+08 1.15E+09 - - - 3.1583 0.9995 221125_WJC_METTL3_EV_vs_WT_F05.06127.06127.2 0.000885 18-Dec R.TASDMVSTSR[166.11].L sp|O00232|PSD12_HUMAN 1 1063.4843 0.66 59599 6127 2 1063.487211 532.7494 26S proteasome non-ATPase regulatory subunit 12 OS=Homo sapiens OX=9606 GN=PSMD12 PE=1 SV=3 5.5 1648.5 - 488026 - - - 2.6959 - 2.188 0.472 - 532.8 1 2 0 0.0029 10 0 0 0 6.05E+06 9.23E+06 - - - 4.7118 0.9979 221125_WJC_METTL3_EV_vs_WT_F05.06132.06132.2 0.107 14-Jul K.ETIMNQEK[136.11].L "sp|P20290|BTF3_HUMAN,tr|A0A7I2V3T6|A0A7I2V3T6_HUMAN,tr|D6RDG3|D6RDG3_HUMAN,tr|A0A7I2YQL2|A0A7I2YQL2_HUMAN" 4 999.4786 0.96 59602 6132 2 999.480461 500.7466 Transcription factor BTF3 OS=Homo sapiens OX=9606 GN=BTF3 PE=1 SV=1 4.53 1649.2 - 2.90E+06 - - - 1.8159 - 1.487 0.286 - 188.5 1 2 0 0.0018 8 0 0 0 6.72E+07 7.00E+07 - - - 2.3494 0.9461 221125_WJC_METTL3_EV_vs_WT_F05.06133.06133.2 0.977 14-Jul K.ETIMNQEK.L "sp|P20290|BTF3_HUMAN,tr|A0A7I2V3T6|A0A7I2V3T6_HUMAN,tr|D6RDG3|D6RDG3_HUMAN,tr|A0A7I2YQL2|A0A7I2YQL2_HUMAN" 4 991.4644 0.96 59603 6133 2 991.46895 496.7395 Transcription factor BTF3 OS=Homo sapiens OX=9606 GN=BTF3 PE=1 SV=1 4.53 1649.2 - 2.26E+06 - - - 4.5428 - 1.44 0.153 - 189.2 1 2 0 0.0045 8 0 0 0 6.72E+07 7.02E+07 - - - 1.2694 0.9985 221125_WJC_METTL3_EV_vs_WT_F05.06134.06134.2 0.00408 22-Dec R.FGGSGSQVDSAR[166.11].M sp|Q13200|PSMD2_HUMAN 1 1176.5399 0.56 59604 6134 2 1176.544364 589.2772 26S proteasome non-ATPase regulatory subunit 2 OS=Homo sapiens OX=9606 GN=PSMD2 PE=1 SV=3 5.84 1649.3 - 833132 - - - 3.8069 - 2.035 0.452 - 325.9 1 2 0 0.0045 12 0 0 0 1.25E+07 2.24E+07 - - - 4.2475 0.9999 221125_WJC_METTL3_EV_vs_WT_F05.06135.06135.2 0.406 22-Dec K.NGGGVGGGELDK.K sp|Q9H7S9|ZN703_HUMAN 1 1058.4993 1.32 59605 6135 2 1058.499705 530.2569 Zinc finger protein 703 OS=Homo sapiens OX=9606 GN=ZNF703 PE=1 SV=1 4.37 1649.4 - 724115 - - - 0.428 - 2.61 0.443 - 496.6 1 2 0 0.0005 12 0 0 0 3.47E+07 2.62E+07 - - - 4.8371 0.9089 221125_WJC_METTL3_EV_vs_WT_F05.06141.06141.2 0.38 24-Nov R.GVVVAGQSQAGAR[166.11].V sp|P0C7T5|ATX1L_HUMAN 1 1208.6501 0.54 59611 6141 2 1208.653386 605.3323 Ataxin-1-like OS=Homo sapiens OX=9606 GN=ATXN1L PE=1 SV=1 9.75 1650.2 - 178891 - - - 2.7154 - 1.305 0.036 - 218.7 1 2 0 0.0033 13 0 0 0 1.21E+08 2.23E+08 - - - -0.0109 0.9997 221125_WJC_METTL3_EV_vs_WT_F05.06148.06148.2 0.000882 16-Aug K.GSSNSYAIK.K "sp|P46782|RS5_HUMAN,tr|M0QZN2|M0QZN2_HUMAN,tr|M0R0F0|M0R0F0_HUMAN,tr|M0R0R2|M0R0R2_HUMAN" 4 925.4505 0.95 59616 6148 2 925.451919 463.7325 40S ribosomal protein S5 OS=Homo sapiens OX=9606 GN=RPS5 PE=1 SV=4 8.59 1651.1 - 721053 - - - 1.5214 - 1.715 0.471 - 272.7 1 2 0 0.0014 9 0 0 0 2.68E+09 2.83E+09 - - - 4.0799 0.9988 221125_WJC_METTL3_EV_vs_WT_F05.06149.06149.2 0.0316 16-Jul K.DDTDDEIAK.Y "sp|P27824|CALX_HUMAN,tr|A0A7P0T937|A0A7P0T937_HUMAN,tr|A0A7P0T840|A0A7P0T840_HUMAN,tr|A0A7P0Z4H2|A0A7P0Z4H2_HUMAN,tr|A0A7P0TB65|A0A7P0TB65_HUMAN,tr|A0A7P0TAN9|A0A7P0TAN9_HUMAN,tr|A0A7P0TAE9|A0A7P0TAE9_HUMAN,tr|A0A7P0T8N1|A0A7P0T8N1_HUMAN,tr|A0A7P0T8G1|A0A7P0T8G1_HUMAN,tr|A0A7P0Z4D6|A0A7P0Z4D6_HUMAN,tr|A0A7P0Z484|A0A7P0Z484_HUMAN,tr|A0A7P0TAR9|A0A7P0TAR9_HUMAN,tr|A0A7P0T9L0|A0A7P0T9L0_HUMAN,tr|D6RAQ8|D6RAQ8_HUMAN,tr|D6RAU8|D6RAU8_HUMAN" 15 1020.4247 1.2 59617 6149 2 1020.425643 511.2197 Calnexin OS=Homo sapiens OX=9606 GN=CANX PE=1 SV=2 3.71 1651.2 - 632105 - - - 0.8761 - 1.402 0.321 - 171.5 1 2 0 0.0009 9 0 0 0 6.52E+07 5.43E+07 - - - 2.3892 0.9816 221125_WJC_METTL3_EV_vs_WT_F05.06150.06150.2 0.0346 16-Oct V.YEGER[166.11]PLTK[136.11].D "sp|P11021|BIP_HUMAN,tr|A0A7P0TAI0|A0A7P0TAI0_HUMAN" 2 1109.5836 0.66 59618 6150 2 1109.584023 555.7991 Endoplasmic reticulum chaperone BiP OS=Homo sapiens OX=9606 GN=HSPA5 PE=1 SV=2 6.14 1651.3 - 368241 - - - 0.3866 - 1.698 0.409 - 214.7 1 1 0 0.0004 9 0 0 0 5.98E+07 9.07E+07 - - - 3.5935 0.9995 221125_WJC_METTL3_EV_vs_WT_F05.06151.06151.2 0.137 24-Oct R.GVVVAGQSQAGAR.V sp|P0C7T5|ATX1L_HUMAN 1 1198.6418 0.54 59619 6151 2 1198.641483 600.3282 Ataxin-1-like OS=Homo sapiens OX=9606 GN=ATXN1L PE=1 SV=1 9.75 1651.4 - 257164 - - - -0.2928 - 2.107 0.274 - 209.3 1 2 0 -0.0003 13 0 0 0 1.21E+08 2.23E+08 - - - 2.9774 0.9862 221125_WJC_METTL3_EV_vs_WT_F05.06155.06155.2 5.23 12-Aug R.FLEQQNK.L "sp|P08670|VIME_HUMAN,sp|Q9NSB2|KRT84_HUMAN,sp|P14136|GFAP_HUMAN,sp|Q14533|KRT81_HUMAN,sp|P48668|K2C6C_HUMAN,sp|P05787|K2C8_HUMAN,sp|Q01546|K22O_HUMAN,sp|P19013|K2C4_HUMAN,sp|Q8N1N4|K2C78_HUMAN,sp|P12035|K2C3_HUMAN,sp|P78386|KRT85_HUMAN,sp|P04259|K2C6B_HUMAN,sp|P13647|K2C5_HUMAN,sp|O43790|KRT86_HUMAN,sp|P78385|KRT83_HUMAN,sp|P08729|K2C7_HUMAN,sp|O95678|K2C75_HUMAN,sp|Q5XKE5|K2C79_HUMAN,sp|P02538|K2C6A_HUMAN,tr|A0A1W2PR46|A0A1W2PR46_HUMAN,tr|F8VUG2|F8VUG2_HUMAN,tr|A0A087X106|A0A087X106_HUMAN,tr|A0A1X7SBR3|A0A1X7SBR3_HUMAN,tr|B4DIR1|B4DIR1_HUMAN,tr|K7EJU1|K7EJU1_HUMAN,tr|F8W0C6|F8W0C6_HUMAN,tr|A0A1X7SCE1|A0A1X7SCE1_HUMAN,tr|Q8IWY7|Q8IWY7_HUMAN,tr|U3KPR1|U3KPR1_HUMAN,tr|F8W1U3|F8W1U3_HUMAN,tr|K7EKH9|K7EKH9_HUMAN,tr|B0YJC4|B0YJC4_HUMAN,tr|K7ELP4|K7ELP4_HUMAN,tr|A0A1B0GTT5|A0A1B0GTT5_HUMAN" 34 905.4607 3.76 59621 6155 2 905.460767 453.7376 Vimentin OS=Homo sapiens OX=9606 GN=VIM PE=1 SV=4 6 1652 - 2.55E+07 - - - 0.095 - 1.084 0.15 - 200.4 1 2 0 0.0001 7 0 0 0 7.46E+08 1.99E+08 - - - 0.4044 0.9998 221125_WJC_METTL3_EV_vs_WT_F05.06159.06159.3 0.000259 Dec-36 K.VVSTHEQVLR.T sp|P02533|K1C14_HUMAN 1 1166.6408 368.3 59625 6159 3 1166.640469 389.8875 "Keratin, type I cytoskeletal 14 OS=Homo sapiens OX=9606 GN=KRT14 PE=1 SV=4" 6.72 1652.2 - 1.17E+06 - - - -0.2589 - 2.357 0.334 - 340.6 1 2 0 -0.0003 10 0 0 0 3.58E+09 9.73E+06 - - - 4.7676 0.9964 221125_WJC_METTL3_EV_vs_WT_F05.06160.06160.2 0.0888 16-Aug K.DDTDDEIAK[136.11].Y "sp|P27824|CALX_HUMAN,tr|A0A7P0T937|A0A7P0T937_HUMAN,tr|A0A7P0T840|A0A7P0T840_HUMAN,tr|A0A7P0Z4H2|A0A7P0Z4H2_HUMAN,tr|A0A7P0TB65|A0A7P0TB65_HUMAN,tr|A0A7P0TAN9|A0A7P0TAN9_HUMAN,tr|A0A7P0TAE9|A0A7P0TAE9_HUMAN,tr|A0A7P0T8N1|A0A7P0T8N1_HUMAN,tr|A0A7P0T8G1|A0A7P0T8G1_HUMAN,tr|A0A7P0Z4D6|A0A7P0Z4D6_HUMAN,tr|A0A7P0Z484|A0A7P0Z484_HUMAN,tr|A0A7P0TAR9|A0A7P0TAR9_HUMAN,tr|A0A7P0T9L0|A0A7P0T9L0_HUMAN,tr|D6RAQ8|D6RAQ8_HUMAN,tr|D6RAU8|D6RAU8_HUMAN" 15 1028.4389 1.25 59626 6160 2 1028.441932 515.2268 Calnexin OS=Homo sapiens OX=9606 GN=CANX PE=1 SV=2 3.71 1652.3 - 467312 - - - 2.9005 - 1.816 0.237 - 288.5 1 2 0 0.003 9 0 0 0 6.52E+07 5.23E+07 - - - 2.5166 0.9973 221125_WJC_METTL3_EV_vs_WT_F05.06161.06161.2 0.00224 18-Sep K.VYEGERPLTK.D "sp|P11021|BIP_HUMAN,tr|A0A7P0TAI0|A0A7P0TAI0_HUMAN" 2 1190.6295 0.41 59627 6161 2 1190.631503 596.322 Endoplasmic reticulum chaperone BiP OS=Homo sapiens OX=9606 GN=HSPA5 PE=1 SV=2 6.11 1652.5 - 457210 - - - 1.6504 - 1.544 0.242 - 239.7 1 2 0 0.002 10 0 0 0 9.18E+07 2.23E+08 - - - 2.0403 0.9972 221125_WJC_METTL3_EV_vs_WT_F05.06162.06162.2 0.00166 18-Nov K.VAQLSSTEC[160.03]R[166.11].T sp|Q5VT06|CE350_HUMAN 1 1159.5531 1.92 59628 6162 2 1159.559172 580.7838 Centrosome-associated protein 350 OS=Homo sapiens OX=9606 GN=CEP350 PE=1 SV=1 5.97 1652.6 - 403871 - - - 5.2434 - 2.375 0.468 - 579.3 1 2 0 0.0061 10 0 0 0 4.45E+07 2.31E+07 - - - 4.9102 0.999 221125_WJC_METTL3_EV_vs_WT_F05.06167.06167.2 5.33E-05 22-Dec K.QLDAGEEATTTK.S sp|O15460|P4HA2_HUMAN 1 1262.599 1.04 59631 6167 2 1262.603143 632.3068 Prolyl 4-hydroxylase subunit alpha-2 OS=Homo sapiens OX=9606 GN=P4HA2 PE=1 SV=1 4.14 1653.3 - 462509 - - - 3.2615 - 1.872 0.484 - 423.4 1 2 0 0.0041 12 0 0 0 1.15E+07 1.11E+07 - - - 4.2643 0.9954 221125_WJC_METTL3_EV_vs_WT_F05.06168.06168.2 0.113 18-Jul K.EVMSPTGSAR.G "sp|O43347|MSI1H_HUMAN,tr|H0YHB7|H0YHB7_HUMAN" 2 1033.4862 0.43 59632 6168 2 1033.487282 517.7504 RNA-binding protein Musashi homolog 1 OS=Homo sapiens OX=9606 GN=MSI1 PE=1 SV=1 6.1 1653.4 - 311349 - - - 1.0044 - 1.349 0.201 - 159.4 1 2 0 0.001 10 0 0 0 1.13E+07 2.62E+07 - - - 1.3609 0.8202 221125_WJC_METTL3_EV_vs_WT_F05.06169.06169.2 2.97 14-Jun K.NNQETMIK.T sp|Q5UIP0|RIF1_HUMAN 1 976.4648 3.8 59633 6169 2 976.465825 489.2397 Telomere-associated protein RIF1 OS=Homo sapiens OX=9606 GN=RIF1 PE=1 SV=2 6 1653.5 - 242131 - - - 1.0692 - 0.82 0.059 - 110.6 1 2 0 0.001 8 0 0 0 2.67E+07 7.02E+06 - - - -1.1221 0.9997 221125_WJC_METTL3_EV_vs_WT_F05.06172.06172.2 0.000143 18-Oct K.VVSTHEQVLR.T sp|P02533|K1C14_HUMAN 1 1166.6408 1525.77 59634 6172 2 1166.641169 584.3277 "Keratin, type I cytoskeletal 14 OS=Homo sapiens OX=9606 GN=KRT14 PE=1 SV=4" 6.72 1653.9 - 772136 - - - 0.3412 - 1.772 0.388 - 367.8 1 2 0 0.0004 10 0 0 0 5.64E+08 3.69E+05 - - - 3.5036 0.9871 221125_WJC_METTL3_EV_vs_WT_F05.06178.06178.2 0.00721 16-Dec V.VSTHEQVLR.T sp|P02533|K1C14_HUMAN 1 1067.5724 999 59637 6178 2 1067.572542 534.7935 "Keratin, type I cytoskeletal 14 OS=Homo sapiens OX=9606 GN=KRT14 PE=1 SV=4" 6.72 1654.7 - 817162 - - - 0.1733 - 2.239 0.354 - 645.2 1 1 0 0.0002 9 0 0 0 3.07E+08 0.00E+00 - - - 3.9875 0.8339 221125_WJC_METTL3_EV_vs_WT_F05.06183.06183.2 3.06 12-Jul K.VK[136.11]DILSK[136.11].V "sp|Q52LJ0|FA98B_HUMAN,tr|H0YNA1|H0YNA1_HUMAN" 2 817.5244 1.02 59639 6183 2 817.523463 409.7695 Protein FAM98B OS=Homo sapiens OX=9606 GN=FAM98B PE=1 SV=2 8.56 1655.5 - 1.17E+06 - - - -1.151 - 1.661 0.01 - 164.7 5 2 1 -0.0009 7 0 0 0 4.23E+07 4.13E+07 - - - 0.4101 0.9939 221125_WJC_METTL3_EV_vs_WT_F05.06187.06187.2 1.29E-05 14-Aug R.YDDPEVQK[136.11].D "sp|P38646|GRP75_HUMAN,tr|H0Y8K0|H0Y8K0_HUMAN,tr|A0A7I2V2S7|A0A7I2V2S7_HUMAN,tr|A0A7I2V2G2|A0A7I2V2G2_HUMAN,tr|A0A3B3ITI4|A0A3B3ITI4_HUMAN,tr|A0A7I2V3F7|A0A7I2V3F7_HUMAN,tr|A0A7I2YQB2|A0A7I2YQB2_HUMAN,tr|D6RCD7|D6RCD7_HUMAN" 8 1000.4593 0.45 59641 6187 2 1000.4539 501.2369 "Stress-70 protein, mitochondrial OS=Homo sapiens OX=9606 GN=HSPA9 PE=1 SV=2" 4.03 1656 - 2.16E+06 - - - -5.3885 - 1.681 0.436 - 161.6 1 2 0 -0.0054 8 0 0 0 1.57E+08 3.50E+08 - - - 3.8261 0.9789 221125_WJC_METTL3_EV_vs_WT_F05.06188.06188.2 7.03 14-Jul K.TEEVSNLK.T "sp|Q6PKG0|LARP1_HUMAN,tr|A0A0B4J210|A0A0B4J210_HUMAN,tr|H0YBW1|H0YBW1_HUMAN,tr|H0YC73|H0YC73_HUMAN,tr|E5RH50|E5RH50_HUMAN" 5 918.4658 5.43 59642 6188 2 918.464614 460.2402 La-related protein 1 OS=Homo sapiens OX=9606 GN=LARP1 PE=1 SV=2 4.53 1656.1 - 1.28E+06 - - - -1.3196 - 1.223 0.094 - 184 1 2 0 -0.0012 8 0 0 0 8.12E+07 1.49E+07 - - - 0.342 0.9999 221125_WJC_METTL3_EV_vs_WT_F05.06191.06191.2 0.00128 22-Nov K.VLVQNAAGSQEK.L sp|Q9Y490|TLN1_HUMAN 1 1242.6568 0.92 59643 6191 2 1242.656468 622.3357 Talin-1 OS=Homo sapiens OX=9606 GN=TLN1 PE=1 SV=3 5.97 1656.5 - 402199 - - - -0.2792 - 1.902 0.529 - 392.3 1 2 0 -0.0003 12 0 0 0 5.00E+07 5.41E+07 - - - 4.6397 0.9918 221125_WJC_METTL3_EV_vs_WT_F05.06193.06193.2 0.971 14-Sep R.YDDPEVQK.D "sp|P38646|GRP75_HUMAN,tr|H0Y8K0|H0Y8K0_HUMAN,tr|A0A7I2V2S7|A0A7I2V2S7_HUMAN,tr|A0A7I2V2G2|A0A7I2V2G2_HUMAN,tr|A0A3B3ITI4|A0A3B3ITI4_HUMAN,tr|A0A7I2V3F7|A0A7I2V3F7_HUMAN,tr|A0A7I2YQB2|A0A7I2YQB2_HUMAN,tr|D6RCD7|D6RCD7_HUMAN" 8 992.4451 0.45 59644 6193 2 992.439054 497.2298 "Stress-70 protein, mitochondrial OS=Homo sapiens OX=9606 GN=HSPA9 PE=1 SV=2" 4.03 1656.7 - 1.21E+06 - - - -6.083 - 1.674 0.472 - 212.9 1 2 0 -0.006 8 0 0 0 1.56E+08 3.50E+08 - - - 4.0792 0.9998 221125_WJC_METTL3_EV_vs_WT_F05.06195.06195.2 0.00475 14-Aug K.GPSFNQER[166.11].G "sp|Q9Y520|PRC2C_HUMAN,tr|A0A0A0MS30|A0A0A0MS30_HUMAN,tr|E7EPN9|E7EPN9_HUMAN" 3 943.4387 0.87 59646 6195 2 943.43859 472.7266 Protein PRRC2C OS=Homo sapiens OX=9606 GN=PRRC2C PE=1 SV=4 6 1656.9 - 1.29E+06 - - - -0.1314 - 1.789 0.409 - 304.8 1 2 0 -0.0001 8 0 0 0 1.49E+08 1.71E+08 - - - 3.8161 0.914 221125_WJC_METTL3_EV_vs_WT_F05.06201.06201.2 0.007 14-Sep V.STHEQVLR.T sp|P02533|K1C14_HUMAN 1 968.5039 5305.8 59648 6201 2 968.501096 485.2592 "Keratin, type I cytoskeletal 14 OS=Homo sapiens OX=9606 GN=KRT14 PE=1 SV=4" 6.47 1657.7 - 8.01E+06 - - - -2.9396 - 1.731 0.36 - 371.9 1 1 0 -0.0028 8 0 0 0 5.25E+08 9.90E+04 - - - 3.3539 0.9979 221125_WJC_METTL3_EV_vs_WT_F05.06207.06207.2 1.41E-06 18-Nov K.EVVEEAENGR[166.11].D "sp|P06454|PTMA_HUMAN,tr|H7C2N1|H7C2N1_HUMAN,tr|B8ZZA1|B8ZZA1_HUMAN,tr|B8ZZW7|B8ZZW7_HUMAN,tr|B8ZZQ6|B8ZZQ6_HUMAN" 5 1140.5287 1.12 59651 6207 2 1140.522694 571.2716 Prothymosin alpha OS=Homo sapiens OX=9606 GN=PTMA PE=1 SV=2 4.09 1658.4 - 1.29E+06 - - - -5.223 - 2.102 0.571 - 501.7 1 2 0 -0.006 10 0 0 0 1.03E+08 9.12E+07 - - - 5.3302 1 221125_WJC_METTL3_EV_vs_WT_F05.06209.06209.2 2.41E-06 22-Dec K.VLVQNAAGSQEK[136.11].L sp|Q9Y490|TLN1_HUMAN 1 1250.671 0.92 59653 6209 2 1250.667993 626.3428 Talin-1 OS=Homo sapiens OX=9606 GN=TLN1 PE=1 SV=3 5.97 1658.6 - 1.03E+06 - - - -2.4163 - 2.309 0.61 - 445.3 1 2 0 -0.003 12 0 0 0 5.00E+07 5.41E+07 - - - 5.7473 0.9386 221125_WJC_METTL3_EV_vs_WT_F05.06218.06218.2 1.22 18-Sep R.VLLGETGK[136.11]EK[136.11].L "sp|P62280|RS11_HUMAN,tr|M0QZC5|M0QZC5_HUMAN,tr|M0R1H6|M0R1H6_HUMAN" 3 1088.6412 0.69 59658 6218 2 1088.637817 545.3279 40S ribosomal protein S11 OS=Homo sapiens OX=9606 GN=RPS11 PE=1 SV=3 6.11 1659.7 - 1.85E+06 - - - -3.1305 - 1.616 0.25 - 249.3 1 2 1 -0.0034 10 0 0 0 1.22E+08 1.77E+08 - - - 2.2261 0.9966 221125_WJC_METTL3_EV_vs_WT_F05.06224.06224.2 0.000556 16-Oct R.VTNLSEDTR[166.11].E "sp|O75821|EIF3G_HUMAN,tr|K7ER90|K7ER90_HUMAN,tr|K7EL20|K7EL20_HUMAN,tr|K7ENA8|K7ENA8_HUMAN" 4 1043.5123 1.03 59662 6224 2 1043.506911 522.7634 Eukaryotic translation initiation factor 3 subunit G OS=Homo sapiens OX=9606 GN=EIF3G PE=1 SV=2 4.37 1660.4 - 1.83E+06 - - - -5.1384 - 2.022 0.452 - 475.6 1 2 0 -0.0054 9 0 0 0 2.14E+08 2.07E+08 - - - 4.4148 0.9998 221125_WJC_METTL3_EV_vs_WT_F05.06228.06228.2 0.000225 18-Sep K.EVVEEAENGR.D "sp|P06454|PTMA_HUMAN,tr|H7C2N1|H7C2N1_HUMAN,tr|B8ZZA1|B8ZZA1_HUMAN,tr|B8ZZW7|B8ZZW7_HUMAN,tr|B8ZZQ6|B8ZZQ6_HUMAN" 5 1130.5204 1.12 59663 6228 2 1130.517951 566.2675 Prothymosin alpha OS=Homo sapiens OX=9606 GN=PTMA PE=1 SV=2 4.09 1661 - 3.31E+06 - - - -2.1495 - 2.187 0.575 - 357.4 1 2 0 -0.0024 10 0 0 0 1.03E+08 9.12E+07 - - - 5.4715 0.9267 221125_WJC_METTL3_EV_vs_WT_F05.06235.06235.2 0.000814 18-Aug M.GLSSQNGQLR.G "sp|P26196|DDX6_HUMAN,tr|Q8IV96|Q8IV96_HUMAN" 2 1058.5469 7.43 59666 6235 2 1058.543914 530.2807 Probable ATP-dependent RNA helicase DDX6 OS=Homo sapiens OX=9606 GN=DDX6 PE=1 SV=2 9.75 1661.8 - 797797 - - - -2.7935 - 1.75 0.382 - 213.7 1 1 0 -0.003 10 0 0 0 1.87E+07 2.52E+06 - - - 3.4236 0.9927 221125_WJC_METTL3_EV_vs_WT_F05.06240.06240.2 0.00299 18-Aug R.VLLGETGKEK.L "sp|P62280|RS11_HUMAN,tr|M0QZC5|M0QZC5_HUMAN,tr|M0R1H6|M0R1H6_HUMAN" 3 1072.6128 0.7 59669 6240 2 1072.613589 537.3137 40S ribosomal protein S11 OS=Homo sapiens OX=9606 GN=RPS11 PE=1 SV=3 6.11 1662.4 - 3.22E+06 - - - 0.7123 - 1.545 0.359 - 202.6 1 2 1 0.0008 10 0 0 0 1.22E+08 1.75E+08 - - - 2.9066 0.9992 221125_WJC_METTL3_EV_vs_WT_F05.06243.06243.2 0.00035 16-Sep R.SQESGYYDR.M "sp|P43243|MATR3_HUMAN,tr|A8MXP9|A8MXP9_HUMAN,tr|D6R991|D6R991_HUMAN,tr|A0A0R4J2E8|A0A0R4J2E8_HUMAN,tr|D6REM6|D6REM6_HUMAN" 5 1103.452 1.36 59671 6243 2 1103.448559 552.7333 Matrin-3 OS=Homo sapiens OX=9606 GN=MATR3 PE=1 SV=2 4.37 1662.7 - 926462 - - - -3.0885 - 1.84 0.487 - 415.6 1 2 0 -0.0034 9 0 0 0 4.39E+07 3.22E+07 - - - 4.401 0.8122 221125_WJC_METTL3_EV_vs_WT_F05.06247.06247.2 2 12-Jun K.TC[160.03]FSPNR.V "sp|O00303|EIF3F_HUMAN,tr|H0YDT6|H0YDT6_HUMAN" 2 880.3861 0.87 59673 6247 2 880.384322 441.2003 Eukaryotic translation initiation factor 3 subunit F OS=Homo sapiens OX=9606 GN=EIF3F PE=1 SV=1 7.91 1663.1 - 1.89E+06 - - - -2.0605 - 0.876 0.072 - 154.1 1 2 0 -0.0018 7 0 0 0 2.95E+07 3.38E+07 - - - -0.8473 0.9964 221125_WJC_METTL3_EV_vs_WT_F05.06248.06248.3 0.00651 Nov-36 R.LRDDTEAAIR.A "sp|P07197|NFM_HUMAN,tr|E7ESP9|E7ESP9_HUMAN,tr|E7EMV2|E7EMV2_HUMAN" 3 1158.5993 2.71 59674 6248 3 1158.596501 387.207 Neurofilament medium polypeptide OS=Homo sapiens OX=9606 GN=NEFM PE=1 SV=3 4.56 1663.3 - 543744 - - - -2.4158 - 1.677 0.37 - 126.9 1 2 1 -0.0028 10 0 0 0 1.91E+08 7.05E+07 - - - 4.1742 0.9274 221125_WJC_METTL3_EV_vs_WT_F05.06252.06252.2 0.429 12-Jun K.TC[160.03]FSPNR[166.11].V "sp|O00303|EIF3F_HUMAN,tr|H0YDT6|H0YDT6_HUMAN" 2 890.3944 0.88 59676 6252 2 890.391122 446.2045 Eukaryotic translation initiation factor 3 subunit F OS=Homo sapiens OX=9606 GN=EIF3F PE=1 SV=1 7.91 1663.8 - 1.04E+06 - - - -3.6883 - 1.014 0.204 - 204.1 1 2 0 -0.0033 7 0 0 0 2.97E+07 3.39E+07 - - - 0.5908 0.9991 221125_WJC_METTL3_EV_vs_WT_F05.06258.06258.2 0.0078 16-Jul R.SQESGYYDR[166.11].M "sp|P43243|MATR3_HUMAN,tr|A8MXP9|A8MXP9_HUMAN,tr|D6R991|D6R991_HUMAN,tr|A0A0R4J2E8|A0A0R4J2E8_HUMAN,tr|D6REM6|D6REM6_HUMAN" 5 1113.4602 1.36 59680 6258 2 1113.457873 557.7374 Matrin-3 OS=Homo sapiens OX=9606 GN=MATR3 PE=1 SV=2 4.37 1664.6 - 1.87E+06 - - - -2.1231 - 1.448 0.438 - 200.1 1 2 0 -0.0024 9 0 0 0 4.39E+07 3.22E+07 - - - 3.3463 0.9998 221125_WJC_METTL3_EV_vs_WT_F05.06265.06265.3 4.55E-06 15/36 R.LR[166.11]DDTEAAIR[166.11].A "sp|P07197|NFM_HUMAN,tr|E7ESP9|E7ESP9_HUMAN,tr|E7EMV2|E7EMV2_HUMAN" 3 1178.6158 2.71 59685 6265 3 1178.612916 393.8792 Neurofilament medium polypeptide OS=Homo sapiens OX=9606 GN=NEFM PE=1 SV=3 4.56 1665.4 - 1.57E+06 - - - -2.4809 - 2.58 0.511 - 628.7 1 2 1 -0.0029 10 0 0 0 1.91E+08 7.05E+07 - - - 7.0043 0.9949 221125_WJC_METTL3_EV_vs_WT_F05.06266.06266.2 0.0059 16-Sep R.VQTESLQER[166.11].F "sp|P20585|MSH3_HUMAN,tr|A0A590UJN8|A0A590UJN8_HUMAN,tr|A0A590UKC9|A0A590UKC9_HUMAN,tr|A0A590UJW0|A0A590UJW0_HUMAN" 4 1098.5545 0.98 59686 6266 2 1098.549901 550.2845 DNA mismatch repair protein Msh3 OS=Homo sapiens OX=9606 GN=MSH3 PE=1 SV=4 4.53 1665.5 - 418020 - - - -4.1609 - 1.691 0.337 - 367.9 1 2 0 -0.0046 9 0 0 0 9.97E+06 1.02E+07 - - - 3.0484 0.9985 221125_WJC_METTL3_EV_vs_WT_F05.06268.06268.2 0.00898 16-Sep R.SAVPPGADK[136.11].K "sp|P46783|RS10_HUMAN,tr|F6U211|F6U211_HUMAN,tr|A0A1W2PQS6|A0A1W2PQS6_HUMAN,tr|A0A2R8YFH6|A0A2R8YFH6_HUMAN,tr|A0A2R8Y7H1|A0A2R8Y7H1_HUMAN,tr|S4R435|S4R435_HUMAN" 6 848.4483 1.11 59688 6268 2 848.446643 425.2314 40S ribosomal protein S10 OS=Homo sapiens OX=9606 GN=RPS10 PE=1 SV=1 5.55 1665.6 - 1.48E+06 - - - -1.9907 - 1.527 0.333 - 269.2 1 2 0 -0.0017 9 0 0 0 8.65E+07 7.77E+07 - - - 2.7247 1 221125_WJC_METTL3_EV_vs_WT_F05.06273.06273.2 8.60E-07 13/22 K.IVQAEGEAEAAK.M "sp|Q99623|PHB2_HUMAN,tr|F5H3X6|F5H3X6_HUMAN,tr|F5GY37|F5GY37_HUMAN" 3 1214.6143 1.32 59691 6273 2 1214.613422 608.3144 Prohibitin-2 OS=Homo sapiens OX=9606 GN=PHB2 PE=1 SV=2 4.25 1666.3 - 1.80E+06 - - - -0.708 - 2.515 0.616 - 591.6 1 2 0 -0.0009 12 0 0 0 1.20E+08 9.06E+07 - - - 6.0172 0.9989 221125_WJC_METTL3_EV_vs_WT_F05.06275.06275.2 0.0685 14-Sep R.NQILQNEK[136.11].K sp|P35580|MYH10_HUMAN 1 993.5335 0.87 59693 6275 2 993.532467 497.774 Myosin-10 OS=Homo sapiens OX=9606 GN=MYH10 PE=1 SV=3 6 1666.5 - 3.67E+06 - - - -0.9985 - 1.613 0.261 - 264.5 1 2 0 -0.001 8 0 0 0 1.35E+08 1.54E+08 - - - 2.4103 0.9999 221125_WJC_METTL3_EV_vs_WT_F05.06276.06276.2 3.41E-06 13/22 K.IVQAEGEAEAAK[136.11].M "sp|Q99623|PHB2_HUMAN,tr|F5H3X6|F5H3X6_HUMAN,tr|F5GY37|F5GY37_HUMAN" 3 1222.6285 1.32 59694 6276 2 1222.628849 612.3215 Prohibitin-2 OS=Homo sapiens OX=9606 GN=PHB2 PE=1 SV=2 4.25 1666.6 - 1.35E+06 - - - 0.3002 - 2.372 0.525 - 427.6 1 2 0 0.0004 12 0 0 0 1.20E+08 9.06E+07 - - - 5.1912 0.9985 221125_WJC_METTL3_EV_vs_WT_F05.06277.06277.2 0.000668 18-Aug K.GEGQLGPAER[166.11].A sp|P13639|EF2_HUMAN 1 1022.502 0.54 59695 6277 2 1022.498972 512.2583 Elongation factor 2 OS=Homo sapiens OX=9606 GN=EEF2 PE=1 SV=4 4.53 1666.7 - 764791 - - - -3.0024 - 1.834 0.366 - 270.4 1 2 0 -0.0031 10 0 0 0 8.81E+07 1.62E+08 - - - 3.4362 0.9982 221125_WJC_METTL3_EV_vs_WT_F05.06282.06282.2 0.00672 14-Aug R.NQILQNEK.K sp|P35580|MYH10_HUMAN 1 985.5193 0.87 59698 6282 2 985.519326 493.7669 Myosin-10 OS=Homo sapiens OX=9606 GN=MYH10 PE=1 SV=3 6 1667.4 - 4.56E+06 - - - 0.068 - 1.593 0.193 - 341.9 1 2 0 0.0001 8 0 0 0 1.35E+08 1.54E+08 - - - 1.8708 0.9988 221125_WJC_METTL3_EV_vs_WT_F05.06283.06283.2 0.861 12-Jul K.ITITNDK[136.11].G "sp|P54652|HSP72_HUMAN,sp|P0DMV8|HS71A_HUMAN,sp|P34931|HS71L_HUMAN,sp|P11142|HSP7C_HUMAN,sp|P0DMV9|HS71B_HUMAN,sp|P17066|HSP76_HUMAN,tr|E9PNE6|E9PNE6_HUMAN,tr|A8K7Q2|A8K7Q2_HUMAN,tr|E9PKE3|E9PKE3_HUMAN,tr|E9PM13|E9PM13_HUMAN,tr|E9PS65|E9PS65_HUMAN,tr|Q53FA3|Q53FA3_HUMAN,tr|V9GZ37|V9GZ37_HUMAN,tr|A0A0G2JIW1|A0A0G2JIW1_HUMAN" 14 811.4531 0.21 59699 6283 2 811.452514 406.7338 Heat shock-related 70 kDa protein 2 OS=Homo sapiens OX=9606 GN=HSPA2 PE=1 SV=1 5.84 1667.4 - 3.69E+06 - - - -0.7012 - 1.533 0.256 - 154.2 1 2 0 -0.0006 7 0 0 0 2.19E+08 1.06E+09 - - - 2.2853 0.9996 221125_WJC_METTL3_EV_vs_WT_F05.06284.06284.2 0.000224 16-Sep R.TATQLAVNK.L "sp|Q99832|TCPH_HUMAN,tr|F8WAM2|F8WAM2_HUMAN" 2 944.5291 0.17 59700 6284 2 944.529672 473.2718 T-complex protein 1 subunit eta OS=Homo sapiens OX=9606 GN=CCT7 PE=1 SV=2 8.41 1667.5 - 3.79E+06 - - - 0.6109 - 1.692 0.389 - 300.7 1 2 0 0.0006 9 0 0 0 3.21E+08 1.85E+09 - - - 3.4355 0.9996 221125_WJC_METTL3_EV_vs_WT_F05.06292.06292.2 0.000573 16-Sep K.GTQVYSPEK.G "sp|O75643|U520_HUMAN,tr|A0A494C1A5|A0A494C1A5_HUMAN" 2 1007.4924 3.86 59705 6292 2 1007.494028 504.7535 U5 small nuclear ribonucleoprotein 200 kDa helicase OS=Homo sapiens OX=9606 GN=SNRNP200 PE=1 SV=2 6 1668.5 - 1.32E+06 - - - 1.6407 - 1.727 0.44 - 433.1 1 2 0 0.0017 9 0 0 0 2.21E+08 5.72E+07 - - - 3.871 0.9998 221125_WJC_METTL3_EV_vs_WT_F05.06294.06294.2 0.000174 16-Oct R.TATQLAVNK[136.11].L "sp|Q99832|TCPH_HUMAN,tr|F8WAM2|F8WAM2_HUMAN" 2 952.5433 0.17 59706 6294 2 952.543401 477.2789 T-complex protein 1 subunit eta OS=Homo sapiens OX=9606 GN=CCT7 PE=1 SV=2 8.41 1668.7 - 4.50E+07 - - - 0.1113 - 1.93 0.44 - 398.1 1 2 0 0.0001 9 0 0 0 3.21E+08 1.85E+09 - - - 4.193 0.9929 221125_WJC_METTL3_EV_vs_WT_F05.06295.06295.2 0.108 14-Jul R.QVEELQQR.L sp|Q9BRP8|PYM1_HUMAN 1 1028.5251 2.71 59707 6295 2 1028.524042 515.2698 Partner of Y14 and mago OS=Homo sapiens OX=9606 GN=PYM1 PE=1 SV=1 4.53 1668.8 - 929355 - - - -1.0024 - 1.483 0.102 - 204.8 1 2 0 -0.001 8 0 0 0 2.63E+07 9.71E+06 - - - 0.9825 0.9859 221125_WJC_METTL3_EV_vs_WT_F05.06296.06296.2 8.84 12-Aug K.LRDDFEK.K "sp|Q9Y2W1|TR150_HUMAN,tr|A0A3B3ITZ9|A0A3B3ITZ9_HUMAN" 2 921.4556 2.27 59708 6296 2 921.45515 461.7351 Thyroid hormone receptor-associated protein 3 OS=Homo sapiens OX=9606 GN=THRAP3 PE=1 SV=2 4.56 1668.9 - 1.87E+06 - - - -0.484 - 1.762 0.182 - 385.4 1 2 1 -0.0004 7 0 0 0 5.22E+09 2.30E+09 - - - 2.1799 1 221125_WJC_METTL3_EV_vs_WT_F05.06301.06301.2 2.22E-05 13/18 R.LRDDTEAAIR.A "sp|P07197|NFM_HUMAN,tr|E7ESP9|E7ESP9_HUMAN,tr|E7EMV2|E7EMV2_HUMAN" 3 1158.5993 2.43 59711 6301 2 1158.598788 580.3069 Neurofilament medium polypeptide OS=Homo sapiens OX=9606 GN=NEFM PE=1 SV=3 4.56 1669.5 - 1.68E+06 - - - -0.4419 - 2.835 0.517 - 336.2 1 2 1 -0.0005 10 0 0 0 4.35E+07 1.79E+07 - - - 5.7681 0.9998 221125_WJC_METTL3_EV_vs_WT_F05.06303.06303.2 9.44E-05 18-Sep K.SATYVNTEGR[166.11].A "sp|P28331|NDUS1_HUMAN,tr|B4DJ81|B4DJ81_HUMAN" 2 1106.5232 1.17 59713 6303 2 1106.52193 554.2689 "NADH-ubiquinone oxidoreductase 75 kDa subunit, mitochondrial OS=Homo sapiens OX=9606 GN=NDUFS1 PE=1 SV=3" 5.72 1669.7 - 1.02E+06 - - - -1.1224 - 1.921 0.471 - 442 1 2 0 -0.0012 10 0 0 0 2.44E+07 2.08E+07 - - - 4.3417 0.9765 221125_WJC_METTL3_EV_vs_WT_F05.06306.06306.2 2.06 12-Jun K.EQSIVEK[136.11].F "sp|Q86U44|MTA70_HUMAN,tr|H0YFV6|H0YFV6_HUMAN" 2 839.448 0.03 59714 6306 2 839.44727 420.7313 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 4.53 1670.1 - 1.89E+06 - - - -0.8672 - 1.202 0.069 - 219.5 1 2 0 -0.0007 7 0 0 0 2.06E+06 6.08E+07 - - - 0.1334 0.9988 221125_WJC_METTL3_EV_vs_WT_F05.06308.06308.2 0.00652 18-Oct R.QEVIGDQADK.L sp|Q9P2D1|CHD7_HUMAN 1 1101.5302 1.16 59716 6308 2 1101.530716 551.7724 Chromodomain-helicase-DNA-binding protein 7 OS=Homo sapiens OX=9606 GN=CHD7 PE=1 SV=3 4.03 1670.3 - 740123 - - - 0.4521 - 1.602 0.258 - 280.6 1 2 0 0.0005 10 0 0 0 2.20E+07 1.90E+07 - - - 2.2618 0.9661 221125_WJC_METTL3_EV_vs_WT_F05.06313.06313.2 0.441 18-Aug R.LFSSSSNTTK[136.11].K "sp|O60271|JIP4_HUMAN,tr|A0A087X2D8|A0A087X2D8_HUMAN" 2 1078.5386 2.45 59718 6313 2 1078.537248 540.2766 C-Jun-amino-terminal kinase-interacting protein 4 OS=Homo sapiens OX=9606 GN=SPAG9 PE=1 SV=4 8.75 1671 - 787915 - - - -1.2573 - 1.193 0.064 - 115.2 1 2 0 -0.0014 10 0 0 0 4.93E+07 2.02E+07 - - - 0.0059 0.9999 221125_WJC_METTL3_EV_vs_WT_F05.06317.06317.2 0.000475 18-Oct R.VQESADELQK[136.11].M "sp|P84085|ARF5_HUMAN,tr|C9J1Z8|C9J1Z8_HUMAN" 2 1153.5706 1.41 59721 6317 2 1153.569929 577.7926 ADP-ribosylation factor 5 OS=Homo sapiens OX=9606 GN=ARF5 PE=1 SV=2 4.14 1671.5 - 3.74E+06 - - - -0.6094 - 2.069 0.521 - 477.9 1 2 0 -0.0007 10 0 0 0 2.78E+08 1.97E+08 - - - 4.9183 0.9943 221125_WJC_METTL3_EV_vs_WT_F05.06323.06323.2 0.000146 14/22 G.PGEVAGTVTGQK[136.11].R "sp|Q86U44|MTA70_HUMAN,tr|F5H6D8|F5H6D8_HUMAN,tr|H0YFV6|H0YFV6_HUMAN,tr|B4DTN4|B4DTN4_HUMAN" 4 1150.6074 0.01 59725 6323 2 1150.607275 576.311 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 6.43 1672.2 - 2.83E+06 - - - -0.0669 - 2.935 0.468 - 830 1 1 0 -0.0001 12 0 0 0 1.03E+06 7.81E+07 - - - 5.3306 0.9965 221125_WJC_METTL3_EV_vs_WT_F05.06324.06324.2 0.0798 20-Jun R.NPPPNSDPNLR[166.11].R sp|Q96I24|FUBP3_HUMAN 1 1229.6028 2.38 59726 6324 2 1229.604952 615.8087 Far upstream element-binding protein 3 OS=Homo sapiens OX=9606 GN=FUBP3 PE=1 SV=2 5.84 1672.3 - 147768 - - - 1.7347 - 1.278 0.296 - 98.2 1 2 0 0.0021 11 0 0 0 1.10E+07 4.61E+06 - - - 1.8902 0.9999 221125_WJC_METTL3_EV_vs_WT_F05.06327.06327.2 0.000123 18-Oct R.VQESADELQK.M "sp|P84085|ARF5_HUMAN,tr|C9J1Z8|C9J1Z8_HUMAN" 2 1145.5564 1.41 59727 6327 2 1145.555667 573.7855 ADP-ribosylation factor 5 OS=Homo sapiens OX=9606 GN=ARF5 PE=1 SV=2 4.14 1672.7 - 3.31E+06 - - - -0.6678 - 2.215 0.551 - 448.1 1 2 0 -0.0008 10 0 0 0 2.79E+08 1.97E+08 - - - 5.3302 0.9992 221125_WJC_METTL3_EV_vs_WT_F05.06328.06328.2 0.0455 18-Jul K.GEGQLGPAER.A sp|P13639|EF2_HUMAN 1 1012.4938 0.49 59728 6328 2 1012.494168 507.2542 Elongation factor 2 OS=Homo sapiens OX=9606 GN=EEF2 PE=1 SV=4 4.53 1672.8 - 1.37E+06 - - - 0.3911 - 1.522 0.333 - 199 1 2 0 0.0004 10 0 0 0 7.57E+07 1.55E+08 - - - 2.6728 0.9989 221125_WJC_METTL3_EV_vs_WT_F05.06329.06329.2 0.0243 18-Aug R.IDPNPADSQK[136.11].S sp|O75663|TIPRL_HUMAN 1 1091.5339 0.86 59729 6329 2 1091.534999 546.7742 TIP41-like protein OS=Homo sapiens OX=9606 GN=TIPRL PE=1 SV=2 4.21 1672.9 - 496186 - - - 1.0499 - 1.596 0.299 - 221.4 1 2 0 0.0011 10 0 0 0 9.63E+06 1.12E+07 - - - 2.554 0.9996 221125_WJC_METTL3_EV_vs_WT_F05.06336.06336.2 0.000111 18-Sep R.QEDPYGPQTK.E sp|O15226|NKRF_HUMAN 1 1161.5302 1.7 59733 6336 2 1161.531386 581.7724 NF-kappa-B-repressing factor OS=Homo sapiens OX=9606 GN=NKRF PE=1 SV=2 4.37 1673.8 - 475231 - - - 1.0056 - 1.701 0.402 - 302.8 1 2 0 0.0012 10 0 0 0 6.04E+07 3.56E+07 - - - 3.4926 0.9991 221125_WJC_METTL3_EV_vs_WT_F05.06344.06344.2 0.00307 18-Aug K.ETSLATPAGK.E sp|Q9UKJ3|GPTC8_HUMAN 1 973.508 3.03 59736 6344 2 973.507378 487.7613 G patch domain-containing protein 8 OS=Homo sapiens OX=9606 GN=GPATCH8 PE=1 SV=2 6.1 1674.8 - 1.14E+06 - - - -0.6656 - 1.728 0.27 - 211.5 1 2 0 -0.0006 10 0 0 0 2.66E+08 8.79E+07 - - - 2.5618 0.9992 221125_WJC_METTL3_EV_vs_WT_F05.06351.06351.2 0.0245 16-Jun K.EGIPPDQQR[166.11].L "sp|P62979|RS27A_HUMAN,sp|P0CG48|UBC_HUMAN,sp|P0CG48|UBC_HUMAN,sp|P0CG48|UBC_HUMAN,sp|P0CG48|UBC_HUMAN,sp|P0CG48|UBC_HUMAN,sp|P0CG48|UBC_HUMAN,sp|P0CG48|UBC_HUMAN,sp|P0CG48|UBC_HUMAN,sp|P0CG48|UBC_HUMAN,sp|P0CG47|UBB_HUMAN,sp|P0CG47|UBB_HUMAN,sp|P0CG47|UBB_HUMAN,sp|P62987|RL40_HUMAN,tr|F5H388|F5H388_HUMAN,tr|F5H388|F5H388_HUMAN,tr|F5GYU3|F5GYU3_HUMAN,tr|F5GYU3|F5GYU3_HUMAN,tr|B4DV12|B4DV12_HUMAN,tr|B4DV12|B4DV12_HUMAN,tr|J3QSA3|J3QSA3_HUMAN,tr|Q5PY61|Q5PY61_HUMAN,tr|Q5PY61|Q5PY61_HUMAN,tr|Q5PY61|Q5PY61_HUMAN,tr|F5H2Z3|F5H2Z3_HUMAN,tr|F5H2Z3|F5H2Z3_HUMAN,tr|M0R2S1|M0R2S1_HUMAN,tr|J3QS39|J3QS39_HUMAN,tr|J3QTR3|J3QTR3_HUMAN,tr|Q96C32|Q96C32_HUMAN,tr|Q96C32|Q96C32_HUMAN,tr|Q96C32|Q96C32_HUMAN,tr|Q96C32|Q96C32_HUMAN,tr|M0R1V7|M0R1V7_HUMAN,tr|F5H747|F5H747_HUMAN,tr|F5H747|F5H747_HUMAN,tr|F5GXK7|F5GXK7_HUMAN,tr|F5GXK7|F5GXK7_HUMAN,tr|M0R1M6|M0R1M6_HUMAN,tr|F5H6Q2|F5H6Q2_HUMAN,tr|F5H6Q2|F5H6Q2_HUMAN,tr|F5GZ39|F5GZ39_HUMAN,tr|J3QKN0|J3QKN0_HUMAN,tr|J3QKN0|J3QKN0_HUMAN,tr|J3QKN0|J3QKN0_HUMAN,tr|F5H265|F5H265_HUMAN,tr|F5H265|F5H265_HUMAN,tr|A0A2R8Y422|A0A2R8Y422_HUMAN" 48 1048.5177 0.49 59741 6351 2 1048.517634 525.2661 Ubiquitin-40S ribosomal protein S27a OS=Homo sapiens OX=9606 GN=RPS27A PE=1 SV=2 4.37 1675.6 - 1.93E+06 - - - -0.0563 - 1.364 0.363 - 126.9 1 2 0 -0.0001 9 0 0 0 3.03E+07 6.16E+07 - - - 2.6202 0.9959 221125_WJC_METTL3_EV_vs_WT_F05.06352.06352.2 0.0252 18-Aug K.ETSLATPAGK[136.11].E sp|Q9UKJ3|GPTC8_HUMAN 1 981.5222 3.03 59742 6352 2 981.523426 491.7684 G patch domain-containing protein 8 OS=Homo sapiens OX=9606 GN=GPATCH8 PE=1 SV=2 6.1 1675.7 - 1.28E+06 - - - 1.2226 - 1.448 0.198 - 210.5 1 2 0 0.0012 10 0 0 0 2.66E+08 8.79E+07 - - - 1.5363 0.9986 221125_WJC_METTL3_EV_vs_WT_F05.06355.06355.2 4.75E-06 18-Sep R.YEGNVTEETR[166.11].L "sp|Q8IY37|DHX37_HUMAN,tr|F5H3Y4|F5H3Y4_HUMAN" 2 1206.5392 0.36 59745 6355 2 1206.533523 604.2769 Probable ATP-dependent RNA helicase DHX37 OS=Homo sapiens OX=9606 GN=DHX37 PE=1 SV=1 4.25 1676 - 186799 - - - -4.7185 - 1.851 0.647 - 218.7 1 2 0 -0.0057 10 0 0 0 1.93E+06 5.31E+06 - - - 5.5366 0.9996 221125_WJC_METTL3_EV_vs_WT_F05.06358.06358.2 0.00581 18-Sep K.AGVSTNISTK[136.11].H "sp|P52948|NUP98_HUMAN,tr|A0A3B3ITD8|A0A3B3ITD8_HUMAN" 2 984.5331 1.82 59746 6358 2 984.532204 493.2738 Nuclear pore complex protein Nup98-Nup96 OS=Homo sapiens OX=9606 GN=NUP98 PE=1 SV=4 8.8 1676.4 - 2.72E+06 - - - -0.9355 - 1.883 0.34 - 191.1 1 2 0 -0.0009 10 0 0 0 1.33E+09 7.30E+08 - - - 3.3185 0.9987 221125_WJC_METTL3_EV_vs_WT_F05.06359.06359.2 0.0883 16-Aug K.ELTDEEAER.L "sp|Q9Y266|NUDC_HUMAN,tr|A0A0A0MSS4|A0A0A0MSS4_HUMAN,tr|A0A0A0MSU9|A0A0A0MSU9_HUMAN" 3 1090.4778 2.09 59747 6359 2 1090.478634 546.2462 Nuclear migration protein nudC OS=Homo sapiens OX=9606 GN=NUDC PE=1 SV=1 3.91 1676.5 - 1.08E+06 - - - 0.7208 - 1.516 0.274 - 309.5 1 2 0 0.0008 9 0 0 0 1.01E+08 4.84E+07 - - - 2.2682 0.9855 221125_WJC_METTL3_EV_vs_WT_F05.06361.06361.2 0.644 12-Jul R.QQELIQK[136.11].K "sp|P46063|RECQ1_HUMAN,tr|F5H3W0|F5H3W0_HUMAN,tr|F5H2L2|F5H2L2_HUMAN,tr|F5GYB7|F5GYB7_HUMAN,tr|F8WD97|F8WD97_HUMAN,tr|F8WA66|F8WA66_HUMAN,tr|F5H4P4|F5H4P4_HUMAN" 7 893.5062 0.63 59749 6361 2 893.505452 447.7604 ATP-dependent DNA helicase Q1 OS=Homo sapiens OX=9606 GN=RECQL PE=1 SV=3 6 1676.8 - 354012 - - - -0.817 - 1.183 0.118 - 200.7 1 2 0 -0.0007 7 0 0 0 2.20E+07 3.49E+07 - - - 0.4448 0.9961 221125_WJC_METTL3_EV_vs_WT_F05.06363.06363.2 0.111 20-Jun R.NPPPNSDPNLR.R sp|Q96I24|FUBP3_HUMAN 1 1219.5945 -1 59751 6363 2 1219.59139 610.8046 Far upstream element-binding protein 3 OS=Homo sapiens OX=9606 GN=FUBP3 PE=1 SV=2 5.84 1677 - 278635 - - - -2.5902 - 1.315 0.332 - 117.7 1 2 0 -0.0032 11 0 0 0 0.00E+00 0.00E+00 - - - 2.233 0.999 221125_WJC_METTL3_EV_vs_WT_F05.06365.06365.2 0.00373 12-Jul R.TPHVPYR.E "sp|P52732|KIF11_HUMAN,tr|A0A7I2YQY4|A0A7I2YQY4_HUMAN,tr|A0A7I2V3A9|A0A7I2V3A9_HUMAN,tr|A0A7I2V3V3|A0A7I2V3V3_HUMAN" 4 868.4555 7.42 59752 6365 2 868.455085 435.235 Kinesin-like protein KIF11 OS=Homo sapiens OX=9606 GN=KIF11 PE=1 SV=2 8.44 1677.2 - 1.15E+07 - - - -0.5193 - 1.271 0.347 - 278.6 1 2 0 -0.0005 7 0 0 0 7.38E+08 9.94E+07 - - - 2.3636 0.9998 221125_WJC_METTL3_EV_vs_WT_F05.06369.06369.2 0.00249 14-Sep R.HLTGEFEK[136.11].K "sp|P62826|RAN_HUMAN,tr|H0YFC6|H0YFC6_HUMAN,tr|B5MDF5|B5MDF5_HUMAN,tr|J3KQE5|J3KQE5_HUMAN,tr|F5H018|F5H018_HUMAN" 5 967.4854 0.9 59755 6369 2 967.485509 484.75 GTP-binding nuclear protein Ran OS=Homo sapiens OX=9606 GN=RAN PE=1 SV=3 5.4 1677.7 - 1.71E+06 - - - 0.0651 - 1.755 0.439 - 264.3 1 2 0 0.0001 8 0 0 0 4.90E+08 5.45E+08 - - - 3.9798 0.999 221125_WJC_METTL3_EV_vs_WT_F05.06370.06370.2 0.0215 14-Jul R.FEK[136.11]PLEEK[136.11].G sp|Q8NC51|PAIRB_HUMAN 1 1034.5619 0.66 59756 6370 2 1034.561695 518.2882 Plasminogen activator inhibitor 1 RNA-binding protein OS=Homo sapiens OX=9606 GN=SERBP1 PE=1 SV=2 4.79 1677.8 - 1.10E+06 - - - -0.2098 - 1.522 0.284 - 172.8 1 2 0 -0.0002 8 0 0 0 3.42E+07 5.19E+07 - - - 2.4053 0.9998 221125_WJC_METTL3_EV_vs_WT_F05.06374.06374.2 0.000142 14-Nov R.HLTGEFEK.K "sp|P62826|RAN_HUMAN,tr|H0YFC6|H0YFC6_HUMAN,tr|B5MDF5|B5MDF5_HUMAN,tr|J3KQE5|J3KQE5_HUMAN,tr|F5H018|F5H018_HUMAN" 5 959.4712 0.9 59758 6374 2 959.469809 480.7429 GTP-binding nuclear protein Ran OS=Homo sapiens OX=9606 GN=RAN PE=1 SV=3 5.4 1678.3 - 2.50E+06 - - - -1.4977 - 2.072 0.491 - 436.5 1 2 0 -0.0014 8 0 0 0 4.88E+08 5.45E+08 - - - 4.8642 0.9005 221125_WJC_METTL3_EV_vs_WT_F05.06375.06375.2 7.29 12-Jun R.HVQLLGR[166.11].S "sp|Q7L576|CYFP1_HUMAN,sp|Q96F07|CYFP2_HUMAN,tr|A0A0G2JR96|A0A0G2JR96_HUMAN,tr|E7EW33|E7EW33_HUMAN,tr|H7C229|H7C229_HUMAN,tr|E7EVJ5|E7EVJ5_HUMAN,tr|A0A0G2JQT1|A0A0G2JQT1_HUMAN" 7 831.4954 1.94 59759 6375 2 831.496086 416.755 Cytoplasmic FMR1-interacting protein 1 OS=Homo sapiens OX=9606 GN=CYFIP1 PE=1 SV=1 9.76 1678.4 - 421338 - - - 0.7757 - 1.096 0.003 - 139.4 2 2 0 0.0006 7 0 0 0 4.72E+07 2.43E+07 - - - -0.7811 0.9811 221125_WJC_METTL3_EV_vs_WT_F05.06381.06381.2 0.0403 12-Aug K.LR[166.11]DDFEK[136.11].K "sp|Q9Y2W1|TR150_HUMAN,tr|A0A3B3ITZ9|A0A3B3ITZ9_HUMAN" 2 939.4781 2.22 59763 6381 2 939.477161 470.7463 Thyroid hormone receptor-associated protein 3 OS=Homo sapiens OX=9606 GN=THRAP3 PE=1 SV=2 4.56 1679 - 5.25E+07 - - - -0.9633 - 1.572 0.213 - 385.8 1 2 1 -0.0009 7 0 0 0 5.22E+09 2.35E+09 - - - 2.0472 0.9994 221125_WJC_METTL3_EV_vs_WT_F05.06385.06385.2 8.74E-05 18-Oct R.QEDPYGPQTK[136.11].E sp|O15226|NKRF_HUMAN 1 1169.5444 1.83 59765 6385 2 1169.54153 585.7795 NF-kappa-B-repressing factor OS=Homo sapiens OX=9606 GN=NKRF PE=1 SV=2 4.37 1679.6 - 712636 - - - -2.4693 - 1.606 0.493 - 396.3 1 2 0 -0.0029 10 0 0 0 6.57E+07 3.59E+07 - - - 4.0038 0.9953 221125_WJC_METTL3_EV_vs_WT_F05.06387.06387.2 0.004 16-Sep R.VDPAFDKDR.F "sp|O43615|TIM44_HUMAN,tr|M0QXM9|M0QXM9_HUMAN" 2 1061.5142 0.98 59766 6387 2 1061.513014 531.7644 Mitochondrial import inner membrane translocase subunit TIM44 OS=Homo sapiens OX=9606 GN=TIMM44 PE=1 SV=2 4.43 1679.8 - 2.36E+06 - - - -1.0928 - 1.721 0.383 - 347.6 1 2 1 -0.0012 9 0 0 0 9.38E+07 9.57E+07 - - - 3.4401 0.9103 221125_WJC_METTL3_EV_vs_WT_F05.06390.06390.2 4.63 12-Jun K.DIAAHIK.K "sp|P63167|DYL1_HUMAN,tr|F8VXL2|F8VXL2_HUMAN,tr|F8VRV5|F8VRV5_HUMAN" 3 766.4337 1.2 59767 6390 2 766.433011 384.2241 "Dynein light chain 1, cytoplasmic OS=Homo sapiens OX=9606 GN=DYNLL1 PE=1 SV=1" 6.74 1680.2 - 3.87E+06 - - - -0.9485 - 0.797 0.129 - 102.1 1 2 0 -0.0007 7 0 0 0 1.65E+08 1.38E+08 - - - -0.7254 0.929 221125_WJC_METTL3_EV_vs_WT_F05.06402.06402.2 0.854 12-Aug R.FK[136.11]NELER[166.11].N "sp|Q2VIR3|IF2GL_HUMAN,sp|P41091|IF2G_HUMAN,tr|H7BZU1|H7BZU1_HUMAN" 3 952.5097 1.42 59773 6402 2 952.509759 477.2621 Eukaryotic translation initiation factor 2 subunit 3B OS=Homo sapiens OX=9606 GN=EIF2S3B PE=2 SV=2 6.14 1681.7 - 1.13E+06 - - - 0.0609 - 1.317 0.132 - 192.9 1 2 1 0.0001 7 0 0 0 7.91E+07 5.58E+07 - - - 0.8884 0.9633 221125_WJC_METTL3_EV_vs_WT_F05.06403.06403.2 1.23 12-Jun K.HVYEIAR.L sp|Q9Y3B7|RM11_HUMAN 1 886.4661 1.2 59774 6403 2 886.466085 444.2403 "39S ribosomal protein L11, mitochondrial OS=Homo sapiens OX=9606 GN=MRPL11 PE=1 SV=1" 6.75 1681.8 - 989406 - - - -0.018 - 1.077 0.084 - 140.1 2 2 0 0 7 0 0 0 7.86E+07 6.55E+07 - - - -0.238 0.9996 221125_WJC_METTL3_EV_vs_WT_F05.06407.06407.2 0.000116 12-Aug K.HVYEIAR[166.11].L sp|Q9Y3B7|RM11_HUMAN 1 896.4744 1.34 59776 6407 2 896.472855 449.2445 "39S ribosomal protein L11, mitochondrial OS=Homo sapiens OX=9606 GN=MRPL11 PE=1 SV=1" 6.75 1682.3 - 1.10E+06 - - - -1.6911 - 1.566 0.456 - 263.3 1 2 0 -0.0015 7 0 0 0 8.84E+07 6.60E+07 - - - 3.8297 0.994 221125_WJC_METTL3_EV_vs_WT_F05.06408.06408.2 0.334 16-Jun K.AC[160.03]GSEIMQK.K sp|P15924|DESP_HUMAN 1 1022.4525 1.92 59777 6408 2 1022.452198 512.2335 Desmoplakin OS=Homo sapiens OX=9606 GN=DSP PE=1 SV=3 6.04 1682.3 - 1.76E+06 - - - -0.2973 - 1.186 0.195 - 121.6 1 2 0 -0.0003 9 0 0 0 4.93E+07 2.57E+07 - - - 0.9747 0.9966 221125_WJC_METTL3_EV_vs_WT_F05.06413.06413.2 0.645 14-Jul K.NTNQDIYR[166.11].E sp|Q8WUA2|PPIL4_HUMAN 1 1032.4864 0.17 59779 6413 2 1032.484437 517.2505 Peptidyl-prolyl cis-trans isomerase-like 4 OS=Homo sapiens OX=9606 GN=PPIL4 PE=1 SV=1 5.84 1682.9 - 817133 - - - -1.8935 - 1.493 0.225 - 225 1 2 0 -0.002 8 0 0 0 6.41E+06 3.76E+07 - - - 1.911 0.9998 221125_WJC_METTL3_EV_vs_WT_F05.06424.06424.2 0.78 16-Oct K.DTGHVYAMK[136.11].L sp|Q15208|STK38_HUMAN 1 1028.4841 3.18 59783 6424 2 1028.483351 515.2493 Serine\threonine-protein kinase 38 OS=Homo sapiens OX=9606 GN=STK38 PE=1 SV=1 6.74 1684.5 - 643359 - - - -0.6952 - 2.095 0.399 - 504.8 1 2 0 -0.0007 9 0 0 0 1.13E+08 3.56E+07 - - - 4.1274 0.9956 221125_WJC_METTL3_EV_vs_WT_F05.06430.06430.2 0.0737 14-Jun K.QDINSLNK.Q "sp|Q13190|STX5_HUMAN,tr|H7C3X5|H7C3X5_HUMAN,tr|E9PNU4|E9PNU4_HUMAN" 3 930.4771 1.87 59785 6430 2 930.477251 466.2458 Syntaxin-5 OS=Homo sapiens OX=9606 GN=STX5 PE=1 SV=2 5.84 1685.3 - 2.30E+06 - - - 0.2053 - 1.287 0.19 - 124.4 1 2 0 0.0002 8 0 0 0 1.07E+08 5.74E+07 - - - 1.2052 0.9999 221125_WJC_METTL3_EV_vs_WT_F05.06436.06436.2 0.144 16-Nov K.DTGHVYAMK.L sp|Q15208|STK38_HUMAN 1 1020.4699 3.17 59788 6436 2 1020.468665 511.2422 Serine\threonine-protein kinase 38 OS=Homo sapiens OX=9606 GN=STK38 PE=1 SV=1 6.74 1685.9 - 2.81E+06 - - - -1.1769 - 2.375 0.491 - 456.6 1 2 0 -0.0012 9 0 0 0 1.13E+08 3.56E+07 - - - 5.1696 0.9924 221125_WJC_METTL3_EV_vs_WT_F05.06439.06439.2 0.097 12-Jul R.SESENWR[166.11].L "sp|Q6Y7W6|GGYF2_HUMAN,tr|I1E4Y6|I1E4Y6_HUMAN,tr|A0A7I2V516|A0A7I2V516_HUMAN,tr|A0A7I2V3H0|A0A7I2V3H0_HUMAN,tr|C9JHW1|C9JHW1_HUMAN,tr|E7ESB6|E7ESB6_HUMAN" 6 916.3914 2.28 59791 6439 2 916.392191 459.203 GRB10-interacting GYF protein 2 OS=Homo sapiens OX=9606 GN=GIGYF2 PE=1 SV=1 4.53 1686.2 - 506030 - - - 0.8315 - 1.124 0.208 - 261 1 2 0 0.0008 7 0 0 0 9.81E+07 4.30E+07 - - - 0.9474 0.963 221125_WJC_METTL3_EV_vs_WT_F05.06450.06450.2 2.18 12-Jul R.HELAQLR.A sp|O75146|HIP1R_HUMAN 1 865.477 0.5 59798 6450 2 865.478667 433.7458 Huntingtin-interacting protein 1-related protein OS=Homo sapiens OX=9606 GN=HIP1R PE=1 SV=2 6.75 1687.6 - 319046 - - - 1.9261 - 1.094 0.127 - 128.9 1 2 0 0.0017 7 0 0 0 8.55E+06 1.70E+07 - - - 0.2632 0.9994 221125_WJC_METTL3_EV_vs_WT_F05.06451.06451.2 0.000734 20-Jul R.LEQNGSPMGAR.G "sp|Q9UPW6|SATB2_HUMAN,tr|F8WCV6|F8WCV6_HUMAN,tr|C9JR56|C9JR56_HUMAN" 3 1158.5452 12.83 59799 6451 2 1158.543684 580.2799 DNA-binding protein SATB2 OS=Homo sapiens OX=9606 GN=SATB2 PE=1 SV=2 6 1687.7 - 234541 - - - -1.2706 - 1.721 0.348 - 157.8 1 2 0 -0.0015 11 0 0 0 6.62E+06 5.16E+05 - - - 3.0796 0.9999 221125_WJC_METTL3_EV_vs_WT_F05.06459.06459.2 5.17E-08 18-Oct R.C[160.03]GDSVYAAEK.L "sp|Q16527|CSRP2_HUMAN,tr|F8VQR7|F8VQR7_HUMAN,tr|F8VW96|F8VW96_HUMAN" 3 1098.4652 0.67 59804 6459 2 1098.466132 550.2399 Cysteine and glycine-rich protein 2 OS=Homo sapiens OX=9606 GN=CSRP2 PE=1 SV=3 4.37 1688.8 - 384968 - - - 0.8712 - 1.945 0.615 - 352.3 1 2 0 0.001 10 0 0 0 1.72E+07 2.56E+07 - - - 5.44 0.9984 221125_WJC_METTL3_EV_vs_WT_F05.06462.06462.2 0.0363 16-Aug R.QQLTNTEVR.R "sp|O60313|OPA1_HUMAN,tr|C9JMB8|C9JMB8_HUMAN,tr|H7C141|H7C141_HUMAN,tr|A0A2R8YDM2|A0A2R8YDM2_HUMAN,tr|E5KLJ9|E5KLJ9_HUMAN,tr|A0A2R8Y3X5|A0A2R8Y3X5_HUMAN,tr|A0A2R8YFD1|A0A2R8YFD1_HUMAN,tr|A0A2R8YE78|A0A2R8YE78_HUMAN" 8 1087.5622 0.61 59805 6462 2 1087.564747 544.7884 "Dynamin-like 120 kDa protein, mitochondrial OS=Homo sapiens OX=9606 GN=OPA1 PE=1 SV=3" 6 1689.2 - 365856 - - - 2.3548 - 1.689 0.318 - 329.9 1 2 0 0.0026 9 0 0 0 1.00E+07 1.63E+07 - - - 2.9053 0.9852 221125_WJC_METTL3_EV_vs_WT_F05.06464.06464.2 0.301 12-May R.SESENWR.L "sp|Q6Y7W6|GGYF2_HUMAN,tr|I1E4Y6|I1E4Y6_HUMAN,tr|A0A7I2V516|A0A7I2V516_HUMAN,tr|A0A7I2V3H0|A0A7I2V3H0_HUMAN,tr|C9JHW1|C9JHW1_HUMAN,tr|E7ESB6|E7ESB6_HUMAN" 6 906.3832 2.28 59806 6464 2 906.384875 454.1989 GRB10-interacting GYF protein 2 OS=Homo sapiens OX=9606 GN=GIGYF2 PE=1 SV=1 4.53 1689.4 - 3.64E+06 - - - 1.8932 - 1.217 0.164 - 115.2 1 2 0 0.0017 7 0 0 0 9.81E+07 4.30E+07 - - - 0.874 1 221125_WJC_METTL3_EV_vs_WT_F05.06465.06465.2 8.95E-07 18-Dec R.C[160.03]GDSVYAAEK[136.11].L "sp|Q16527|CSRP2_HUMAN,tr|F8VQR7|F8VQR7_HUMAN,tr|F8VW96|F8VW96_HUMAN" 3 1106.4794 0.67 59807 6465 2 1106.481606 554.247 Cysteine and glycine-rich protein 2 OS=Homo sapiens OX=9606 GN=CSRP2 PE=1 SV=3 4.37 1689.5 - 934947 - - - 2.0163 - 2.126 0.65 - 581.6 1 2 0 0.0022 10 0 0 0 1.72E+07 2.56E+07 - - - 5.9465 0.998 221125_WJC_METTL3_EV_vs_WT_F05.06471.06471.2 0.000198 14-Aug R.SDLYSSGR.D "sp|P38159|RBMX_HUMAN,tr|H3BUY5|H3BUY5_HUMAN" 2 883.4036 1.42 59811 6471 2 883.40447 442.7091 "RNA-binding motif protein, X chromosome OS=Homo sapiens OX=9606 GN=RBMX PE=1 SV=3" 5.55 1690.4 - 1.44E+06 - - - 1.0301 - 1.758 0.175 - 248.8 1 2 0 0.0009 8 0 0 0 1.94E+08 1.37E+08 - - - 2.0348 0.9982 221125_WJC_METTL3_EV_vs_WT_F05.06472.06472.2 0.232 14-Jun R.SDLYSSGR[166.11].D "sp|P38159|RBMX_HUMAN,tr|H3BUY5|H3BUY5_HUMAN" 2 893.4118 1.42 59812 6472 2 893.413007 447.7132 "RNA-binding motif protein, X chromosome OS=Homo sapiens OX=9606 GN=RBMX PE=1 SV=3" 5.55 1690.5 - 1.35E+06 - - - 1.3174 - 1.523 0.259 - 135.9 1 2 0 0.0012 8 0 0 0 1.94E+08 1.37E+08 - - - 2.2224 0.9926 221125_WJC_METTL3_EV_vs_WT_F05.06475.06475.2 0.000355 12-Aug T.GHVYAMK.L sp|Q15208|STK38_HUMAN 1 804.3952 2.46 59815 6475 2 804.395631 403.2049 Serine\threonine-protein kinase 38 OS=Homo sapiens OX=9606 GN=STK38 PE=1 SV=1 8.6 1690.8 - 801523 - - - 0.4811 - 1.886 0.529 - 385.8 1 1 0 0.0004 7 0 0 0 3.35E+07 1.36E+07 - - - 4.9584 0.9991 221125_WJC_METTL3_EV_vs_WT_F05.06476.06476.2 0.00161 18-Jul K.AAPQSPSVPK.K "sp|O75694|NU155_HUMAN,tr|E9PF10|E9PF10_HUMAN" 2 980.5291 1.29 59816 6476 2 980.529526 491.2718 Nuclear pore complex protein Nup155 OS=Homo sapiens OX=9606 GN=NUP155 PE=1 SV=1 8.8 1690.9 - 325739 - - - 0.4396 - 1.499 0.318 - 164.6 1 2 0 0.0004 10 0 0 0 7.74E+07 5.99E+07 - - - 2.5195 0.9995 221125_WJC_METTL3_EV_vs_WT_F05.06477.06477.2 1.79E-05 20-Dec R.EAGEQGDIEPR.R "sp|Q13283|G3BP1_HUMAN,tr|A0A7I2V5M7|A0A7I2V5M7_HUMAN,tr|A0A7I2V496|A0A7I2V496_HUMAN,tr|A0A7I2V2X7|A0A7I2V2X7_HUMAN,tr|A0A7P0P2U7|A0A7P0P2U7_HUMAN,tr|A0A7I2V548|A0A7I2V548_HUMAN,tr|A0A7I2YQN9|A0A7I2YQN9_HUMAN" 7 1199.5418 1.22 59817 6477 2 1199.545299 600.7782 Ras GTPase-activating protein-binding protein 1 OS=Homo sapiens OX=9606 GN=G3BP1 PE=1 SV=1 4 1691.1 - 126380 - - - 2.8794 - 2.006 0.551 - 548.7 1 2 0 0.0035 11 0 0 0 8.99E+08 7.40E+08 - - - 4.9928 0.9981 221125_WJC_METTL3_EV_vs_WT_F05.06482.06482.2 0.0502 16-Jun K.DVDSAYMNK.V sp|P12035|K2C3_HUMAN 1 1041.4437 1146.01 59820 6482 2 1041.444448 521.7291 "Keratin, type II cytoskeletal 3 OS=Homo sapiens OX=9606 GN=KRT3 PE=1 SV=3" 4.21 1691.7 - 1.10E+06 - - - 0.7077 - 1.172 0.334 - 77.9 1 2 0 0.0007 9 0 0 0 2.92E+09 2.55E+06 - - - 1.9669 1 221125_WJC_METTL3_EV_vs_WT_F05.06484.06484.2 0.000133 13/22 K.VGGTSDVEVNEK.K "sp|P10809|CH60_HUMAN,tr|A0A7I2V2X6|A0A7I2V2X6_HUMAN,tr|A0A7I2YQK6|A0A7I2YQK6_HUMAN,tr|A0A7I2V599|A0A7I2V599_HUMAN" 4 1232.5885 1.3 59822 6484 2 1232.589154 617.3015 "60 kDa heat shock protein, mitochondrial OS=Homo sapiens OX=9606 GN=HSPD1 PE=1 SV=2" 4.14 1691.8 - 734919 - - - 0.5622 - 2.792 0.574 - 790.7 1 2 0 0.0007 12 0 0 0 3.72E+09 2.87E+09 - - - 5.9819 1 221125_WJC_METTL3_EV_vs_WT_F05.06485.06485.2 1.60E-06 13/22 K.VGGTSDVEVNEK[136.11].K "sp|P10809|CH60_HUMAN,tr|A0A7I2V2X6|A0A7I2V2X6_HUMAN,tr|A0A7I2YQK6|A0A7I2YQK6_HUMAN,tr|A0A7I2V599|A0A7I2V599_HUMAN" 4 1240.6027 1.3 59823 6485 2 1240.602069 621.3086 "60 kDa heat shock protein, mitochondrial OS=Homo sapiens OX=9606 GN=HSPD1 PE=1 SV=2" 4.14 1692 - 733073 - - - -0.4772 - 2.867 0.595 - 816.9 1 2 0 -0.0006 12 0 0 0 3.72E+09 2.87E+09 - - - 6.2068 0.9808 221125_WJC_METTL3_EV_vs_WT_F05.06486.06486.2 0.473 12-Jun K.C[160.03]DLEDER.V "sp|A6NIZ1|RP1BL_HUMAN,sp|P62834|RAP1A_HUMAN,sp|P61224|RAP1B_HUMAN,sp|O95716|RAB3D_HUMAN,tr|F5H7Y6|F5H7Y6_HUMAN,tr|E7ESV4|E7ESV4_HUMAN,tr|F5GX62|F5GX62_HUMAN,tr|A0A075B6Q0|A0A075B6Q0_HUMAN,tr|F5H004|F5H004_HUMAN,tr|B7ZB78|B7ZB78_HUMAN,tr|F5GZG1|F5GZG1_HUMAN,tr|F5H823|F5H823_HUMAN" 12 935.3655 0.88 59824 6486 2 935.369082 468.69 Ras-related protein Rap-1b-like protein OS=Homo sapiens OX=9606 PE=2 SV=1 3.92 1692.1 - 422169 - - - 3.8712 - 1.147 0.301 - 151 1 2 0 0.0036 7 0 0 0 3.88E+06 4.39E+06 - - - 1.6976 0.9937 221125_WJC_METTL3_EV_vs_WT_F05.06489.06489.2 0.00113 14-Sep K.VTEK[136.11]IPVR[166.11].H "sp|Q00839|HNRPU_HUMAN,tr|A0A1W2PQL0|A0A1W2PQL0_HUMAN,tr|A0A1W2PPL4|A0A1W2PPL4_HUMAN,tr|A0A1W2PQ74|A0A1W2PQ74_HUMAN,tr|Q5RI18|Q5RI18_HUMAN,tr|A0A1W2PP35|A0A1W2PP35_HUMAN,tr|A0A1W2PPS1|A0A1W2PPS1_HUMAN,tr|A0A1W2PRZ7|A0A1W2PRZ7_HUMAN,tr|A0A1W2PPH7|A0A1W2PPH7_HUMAN,tr|A0A1W2PP34|A0A1W2PP34_HUMAN,tr|A0A1X7SBS1|A0A1X7SBS1_HUMAN" 11 958.593 0.9 59825 6489 2 958.594301 480.3038 Heterogeneous nuclear ribonucleoprotein U OS=Homo sapiens OX=9606 GN=HNRNPU PE=1 SV=6 8.72 1692.5 - 2.85E+06 - - - 1.3196 - 1.989 0.304 - 470.8 1 2 1 0.0013 8 0 0 0 1.30E+08 1.44E+08 - - - 3.3598 0.9999 221125_WJC_METTL3_EV_vs_WT_F05.06490.06490.2 1.19E-06 20-Dec R.EAGEQGDIEPR[166.11].R "sp|Q13283|G3BP1_HUMAN,tr|A0A7I2V5M7|A0A7I2V5M7_HUMAN,tr|A0A7I2V496|A0A7I2V496_HUMAN,tr|A0A7I2V2X7|A0A7I2V2X7_HUMAN,tr|A0A7P0P2U7|A0A7P0P2U7_HUMAN,tr|A0A7I2V548|A0A7I2V548_HUMAN,tr|A0A7I2YQN9|A0A7I2YQN9_HUMAN" 7 1209.5501 1.23 59826 6490 2 1209.549665 605.7823 Ras GTPase-activating protein-binding protein 1 OS=Homo sapiens OX=9606 GN=G3BP1 PE=1 SV=1 4 1692.6 - 1.21E+06 - - - -0.372 - 2.129 0.509 - 562.3 1 2 0 -0.0004 11 0 0 0 8.99E+08 7.30E+08 - - - 4.8446 0.9992 221125_WJC_METTL3_EV_vs_WT_F05.06492.06492.2 0.0591 14-Aug R.DSEIMQQK.Q sp|P84101|SERF2_HUMAN 1 977.4488 0.8 59828 6492 2 977.448735 489.7317 Small EDRK-rich factor 2 OS=Homo sapiens OX=9606 GN=SERF2 PE=1 SV=1 4.37 1692.7 - 735132 - - - -0.0624 - 1.55 0.294 - 371.4 1 2 0 -0.0001 8 0 0 0 3.29E+07 4.10E+07 - - - 2.5342 0.9988 221125_WJC_METTL3_EV_vs_WT_F05.06498.06498.2 0.0213 16-Aug K.TSSSQGIIR.N sp|Q8WWK9|CKAP2_HUMAN 1 947.5036 0.74 59832 6498 2 947.503957 474.7591 Cytoskeleton-associated protein 2 OS=Homo sapiens OX=9606 GN=CKAP2 PE=1 SV=1 9.41 1693.5 - 1.20E+06 - - - 0.3673 - 1.782 0.207 - 277.1 1 2 0 0.0003 9 0 0 0 3.48E+07 4.68E+07 - - - 2.2412 0.997 221125_WJC_METTL3_EV_vs_WT_F05.06500.06500.2 1.22 14-Aug R.DSEIMQQK[136.11].Q sp|P84101|SERF2_HUMAN 1 985.463 0.8 59833 6500 2 985.463524 493.7388 Small EDRK-rich factor 2 OS=Homo sapiens OX=9606 GN=SERF2 PE=1 SV=1 4.37 1693.8 - 1.31E+06 - - - 0.5358 - 1.562 0.159 - 274.8 1 2 0 0.0005 8 0 0 0 3.29E+07 4.10E+07 - - - 1.5602 0.9972 221125_WJC_METTL3_EV_vs_WT_F05.06504.06504.2 0.000107 18-Sep K.ENGAAALDGR.L "sp|P57105|SYJ2B_HUMAN,tr|A0A087X1F5|A0A087X1F5_HUMAN,tr|A0A087WYV9|A0A087WYV9_HUMAN" 3 972.4625 1.72 59834 6504 2 972.458027 487.2385 Synaptojanin-2-binding protein OS=Homo sapiens OX=9606 GN=SYNJ2BP PE=1 SV=2 4.37 1694.3 - 519013 - - - -4.5709 - 1.769 0.467 - 278.6 1 2 0 -0.0044 10 0 0 0 3.15E+07 1.83E+07 - - - 4.0811 0.7641 221125_WJC_METTL3_EV_vs_WT_F05.06511.06511.2 0.0328 16-Aug V.GLEPPPGK[136.11]R[166.11].E "sp|Q9BSD7|NTPCR_HUMAN,tr|Q5TDF0|Q5TDF0_HUMAN" 2 967.557 1.5 59838 6511 2 967.557884 484.7858 Cancer-related nucleoside-triphosphatase OS=Homo sapiens OX=9606 GN=NTPCR PE=1 SV=1 8.75 1695.1 - 801810 - - - 0.9291 - 1.345 0.185 - 177.7 1 1 0 0.0009 9 0 0 0 6.71E+07 4.48E+07 - - - 1.2646 0.9988 221125_WJC_METTL3_EV_vs_WT_F05.06512.06512.2 0.0272 18-Oct K.LQVSQTEPAK.S sp|Q96T58|MINT_HUMAN 1 1099.5873 1.25 59839 6512 2 1099.589335 550.8009 Msx2-interacting protein OS=Homo sapiens OX=9606 GN=SPEN PE=1 SV=1 6 1695.3 - 459257 - - - 1.8152 - 1.842 0.286 - 336.5 1 2 0 0.002 10 0 0 0 2.65E+07 2.13E+07 - - - 2.8578 0.9871 221125_WJC_METTL3_EV_vs_WT_F05.06513.06513.2 5 18-Jun R.IVGHLTHALK.Q "sp|P24752|THIL_HUMAN,tr|A0A5F9ZHD4|A0A5F9ZHD4_HUMAN,tr|A0A5F9ZHJ0|A0A5F9ZHJ0_HUMAN,tr|A0A5F9ZHL1|A0A5F9ZHL1_HUMAN,tr|A0A5F9ZI66|A0A5F9ZI66_HUMAN" 5 1087.6502 1.19 59840 6513 2 1087.648518 544.8324 "Acetyl-CoA acetyltransferase, mitochondrial OS=Homo sapiens OX=9606 GN=ACAT1 PE=1 SV=1" 8.76 1695.4 - 405275 - - - -1.5593 - 1.19 0.186 - 92.3 2 2 0 -0.0017 10 0 0 0 6.29E+06 5.27E+06 - - - 0.7653 0.9196 221125_WJC_METTL3_EV_vs_WT_F05.06517.06517.2 0.105 14-Jun K.VTEKIPVR.H "sp|Q00839|HNRPU_HUMAN,tr|A0A1W2PQL0|A0A1W2PQL0_HUMAN,tr|A0A1W2PPL4|A0A1W2PPL4_HUMAN,tr|A0A1W2PQ74|A0A1W2PQ74_HUMAN,tr|Q5RI18|Q5RI18_HUMAN,tr|A0A1W2PP35|A0A1W2PP35_HUMAN,tr|A0A1W2PPS1|A0A1W2PPS1_HUMAN,tr|A0A1W2PRZ7|A0A1W2PRZ7_HUMAN,tr|A0A1W2PPH7|A0A1W2PPH7_HUMAN,tr|A0A1W2PP34|A0A1W2PP34_HUMAN,tr|A0A1X7SBS1|A0A1X7SBS1_HUMAN" 11 940.5706 0.91 59842 6517 2 940.570075 471.2926 Heterogeneous nuclear ribonucleoprotein U OS=Homo sapiens OX=9606 GN=HNRNPU PE=1 SV=6 8.72 1696 - 3.81E+06 - - - -0.522 - 1.485 0.097 - 123.4 2 2 1 -0.0005 8 0 0 0 1.30E+08 1.44E+08 - - - 0.8154 0.999 221125_WJC_METTL3_EV_vs_WT_F05.06518.06518.2 0.0654 18-Aug R.VGLEPPPGK[136.11]R[166.11].E "sp|Q9BSD7|NTPCR_HUMAN,tr|Q5TDF0|Q5TDF0_HUMAN" 2 1066.6254 1.09 59843 6518 2 1066.624697 534.32 Cancer-related nucleoside-triphosphatase OS=Homo sapiens OX=9606 GN=NTPCR PE=1 SV=1 8.72 1696.1 - 1.12E+06 - - - -0.6582 - 1.613 0.272 - 239.6 1 2 0 -0.0007 10 0 0 0 5.70E+07 5.23E+07 - - - 2.3843 0.999 221125_WJC_METTL3_EV_vs_WT_F05.06522.06522.2 0.353 14-Aug R.MQEENITR.A "sp|P19388|RPAB1_HUMAN,tr|A0A0A0MQR7|A0A0A0MQR7_HUMAN,tr|A0A087WVZ9|A0A087WVZ9_HUMAN,tr|A0A087WWX0|A0A087WWX0_HUMAN,tr|A0A087WVN5|A0A087WVN5_HUMAN" 5 1019.4706 1.52 59845 6522 2 1019.469741 510.7426 "DNA-directed RNA polymerases I, II, and III subunit RPABC1 OS=Homo sapiens OX=9606 GN=POLR2E PE=1 SV=4" 4.53 1696.6 - 1.40E+06 - - - -0.8367 - 1.647 0.266 - 268.8 1 2 0 -0.0009 8 0 0 0 5.70E+07 3.75E+07 - - - 2.5102 0.9181 221125_WJC_METTL3_EV_vs_WT_F05.06525.06525.2 0.0441 16-Jul N.FQQPADAER[166.11].A "sp|Q13310|PABP4_HUMAN,sp|Q4VXU2|PAP1L_HUMAN,sp|P11940|PABP1_HUMAN,tr|A0A7I2V649|A0A7I2V649_HUMAN,tr|B1ANR0|B1ANR0_HUMAN,tr|A0A6Q8JFT6|A0A6Q8JFT6_HUMAN,tr|A0A7I2V4L7|A0A7I2V4L7_HUMAN,tr|E5RHG7|E5RHG7_HUMAN,tr|B1ANR1|B1ANR1_HUMAN,tr|H0YAR2|H0YAR2_HUMAN,tr|E7ERJ7|E7ERJ7_HUMAN,tr|E5RJB9|E5RJB9_HUMAN,tr|A0A7I2YQ88|A0A7I2YQ88_HUMAN,tr|H0YEQ8|H0YEQ8_HUMAN,tr|E5RH24|E5RH24_HUMAN,tr|H0YBN4|H0YBN4_HUMAN,tr|E5RGH3|E5RGH3_HUMAN,tr|A0A087WTT1|A0A087WTT1_HUMAN,tr|A0A7I2YQ90|A0A7I2YQ90_HUMAN,tr|A0A6Q8JFV4|A0A6Q8JFV4_HUMAN,tr|E7EQV3|E7EQV3_HUMAN" 21 1070.502 2.44 59847 6525 2 1070.503082 536.2583 Polyadenylate-binding protein 4 OS=Homo sapiens OX=9606 GN=PABPC4 PE=1 SV=1 4.37 1696.9 - 385333 - - - 0.9715 - 1.421 0.298 - 170.9 1 1 0 0.001 9 0 0 0 1.24E+08 5.08E+07 - - - 2.2582 0.9968 221125_WJC_METTL3_EV_vs_WT_F05.06528.06528.2 0.267 16-Aug R.TTGDISVEK.L "sp|Q16512|PKN1_HUMAN,tr|K7EN76|K7EN76_HUMAN" 2 948.4764 1.86 59848 6528 2 948.476334 475.2455 Serine\threonine-protein kinase N1 OS=Homo sapiens OX=9606 GN=PKN1 PE=1 SV=2 4.37 1697.3 - 2.01E+06 - - - -0.0601 - 1.447 0.177 - 241.5 1 2 0 -0.0001 9 0 0 0 5.79E+07 3.11E+07 - - - 1.4173 0.998 221125_WJC_METTL3_EV_vs_WT_F05.06530.06530.2 0.00382 12-Aug R.KGFIDGR.A sp|P15924|DESP_HUMAN 1 791.429 2.73 59850 6530 2 791.427681 396.7218 Desmoplakin OS=Homo sapiens OX=9606 GN=DSP PE=1 SV=3 8.75 1697.6 - 985586 - - - -1.6502 - 1.55 0.244 - 219.9 1 2 0 -0.0013 7 0 0 0 3.63E+07 1.33E+07 - - - 2.2314 0.926 221125_WJC_METTL3_EV_vs_WT_F05.06532.06532.2 0.714 12-Jul R.K[136.11]GFIDGR[166.11].A sp|P15924|DESP_HUMAN 1 809.4515 3.28 59852 6532 2 809.446852 405.733 Desmoplakin OS=Homo sapiens OX=9606 GN=DSP PE=1 SV=3 8.75 1697.8 - 321057 - - - -5.689 - 1.234 0.257 - 207.5 1 2 0 -0.0046 7 0 0 0 3.53E+07 1.08E+07 - - - 1.604 0.9994 221125_WJC_METTL3_EV_vs_WT_F05.06536.06536.2 0.318 18-Sep R.VGLEPPPGKR.E "sp|Q9BSD7|NTPCR_HUMAN,tr|Q5TDF0|Q5TDF0_HUMAN" 2 1048.6029 1.09 59854 6536 2 1048.600828 525.3087 Cancer-related nucleoside-triphosphatase OS=Homo sapiens OX=9606 GN=NTPCR PE=1 SV=1 8.72 1698.3 - 1.90E+06 - - - -2.0036 - 1.887 0.382 - 204.6 1 2 0 -0.0021 10 0 0 0 5.70E+07 5.23E+07 - - - 3.6342 0.9999 221125_WJC_METTL3_EV_vs_WT_F05.06538.06538.2 2.91E-05 18-Nov K.LESENDEYER.A sp|O94906|PRP6_HUMAN 1 1282.5313 2.87 59856 6538 2 1282.531257 642.2729 Pre-mRNA-processing factor 6 OS=Homo sapiens OX=9606 GN=PRPF6 PE=1 SV=1 3.91 1698.5 - 807024 - - - -0.0647 - 1.842 0.592 - 445.9 1 2 0 -0.0001 10 0 0 0 7.38E+07 2.57E+07 - - - 5.1186 0.9995 221125_WJC_METTL3_EV_vs_WT_F05.06539.06539.2 0.000513 20-Nov K.AISEAQESVTK[136.11].T "sp|Q6PJT7|ZC3HE_HUMAN,tr|G3V256|G3V256_HUMAN,tr|H0YJ87|H0YJ87_HUMAN,tr|G3V5I6|G3V5I6_HUMAN,tr|H0YJA2|H0YJA2_HUMAN,tr|A0A087WTC9|A0A087WTC9_HUMAN" 6 1169.6019 0.96 59857 6539 2 1169.600596 585.8082 Zinc finger CCCH domain-containing protein 14 OS=Homo sapiens OX=9606 GN=ZC3H14 PE=1 SV=1 4.53 1698.6 - 457605 - - - -1.1431 - 2.06 0.322 - 298.9 1 2 0 -0.0013 11 0 0 0 7.45E+07 7.74E+07 - - - 3.374 0.9996 221125_WJC_METTL3_EV_vs_WT_F05.06540.06540.2 0.114 18-Sep R.SLNQDVATTK[136.11].E "sp|Q9BYP7|WNK3_HUMAN,tr|A0A087WYK2|A0A087WYK2_HUMAN" 2 1083.5652 0.67 59858 6540 2 1083.563753 542.7899 Serine\threonine-protein kinase WNK3 OS=Homo sapiens OX=9606 GN=WNK3 PE=1 SV=3 5.55 1698.8 - 220597 - - - -1.292 - 1.769 0.408 - 211.7 1 2 0 -0.0014 10 0 0 0 8.62E+06 1.28E+07 - - - 3.6462 0.9926 221125_WJC_METTL3_EV_vs_WT_F05.06543.06543.2 0.0034 14-Aug K.QTSLSVSR.E "sp|Q5VWN6|TASO2_HUMAN,tr|A0A2R8YH03|A0A2R8YH03_HUMAN" 2 876.4665 0.09 59859 6543 2 876.46482 439.2405 Protein TASOR 2 OS=Homo sapiens OX=9606 GN=TASOR2 PE=1 SV=1 9.75 1699.2 - 642670 - - - -1.9111 - 1.813 0.067 - 237.2 1 2 0 -0.0017 8 0 0 0 1.14E+07 1.24E+08 - - - 1.3298 0.9999 221125_WJC_METTL3_EV_vs_WT_F05.06545.06545.2 8.17E-05 20-Oct K.AISEAQESVTK.T "sp|Q6PJT7|ZC3HE_HUMAN,tr|G3V256|G3V256_HUMAN,tr|H0YJ87|H0YJ87_HUMAN,tr|G3V5I6|G3V5I6_HUMAN,tr|H0YJA2|H0YJA2_HUMAN,tr|A0A087WTC9|A0A087WTC9_HUMAN" 6 1161.5877 0.96 59861 6545 2 1161.587146 581.8011 Zinc finger CCCH domain-containing protein 14 OS=Homo sapiens OX=9606 GN=ZC3H14 PE=1 SV=1 4.53 1699.4 - 1.23E+06 - - - -0.5053 - 2.13 0.478 - 248.7 1 2 0 -0.0006 11 0 0 0 7.45E+07 7.74E+07 - - - 4.6168 1 221125_WJC_METTL3_EV_vs_WT_F05.06548.06548.2 5.81E-06 18-Nov K.LESENDEYER[166.11].A sp|O94906|PRP6_HUMAN 1 1292.5396 2.87 59862 6548 2 1292.535067 647.2771 Pre-mRNA-processing factor 6 OS=Homo sapiens OX=9606 GN=PRPF6 PE=1 SV=1 3.91 1699.8 - 900577 - - - -3.5148 - 2.107 0.628 - 426.6 1 2 0 -0.0045 10 0 0 0 7.38E+07 2.57E+07 - - - 5.7582 0.9998 221125_WJC_METTL3_EV_vs_WT_F05.06549.06549.2 6.36E-06 18-Oct K.YTAQVDAEEK.E sp|O75947|ATP5H_HUMAN 1 1152.5299 0.68 59863 6549 2 1152.528704 577.2722 "ATP synthase subunit d, mitochondrial OS=Homo sapiens OX=9606 GN=ATP5PD PE=1 SV=3" 4.14 1699.9 - 587507 - - - -1.023 - 1.897 0.538 - 308.3 1 2 0 -0.0012 10 0 0 0 2.09E+07 3.05E+07 - - - 4.8015 0.9986 221125_WJC_METTL3_EV_vs_WT_F05.06550.06550.2 0.000175 18-Oct R.SLNQDVATTK.E "sp|Q9BYP7|WNK3_HUMAN,tr|A0A087WYK2|A0A087WYK2_HUMAN" 2 1075.551 0.67 59864 6550 2 1075.554496 538.7828 Serine\threonine-protein kinase WNK3 OS=Homo sapiens OX=9606 GN=WNK3 PE=1 SV=3 5.55 1700.1 - 762416 - - - 3.2941 - 1.749 0.431 - 235.7 1 2 0 0.0035 10 0 0 0 8.62E+06 1.28E+07 - - - 3.7837 0.9999 221125_WJC_METTL3_EV_vs_WT_F05.06551.06551.3 0.00209 14/36 R.LPDAHSDYAR[166.11].Y sp|Q96PK6|RBM14_HUMAN 1 1153.5392 1.93 59865 6551 3 1153.537242 385.5203 RNA-binding protein 14 OS=Homo sapiens OX=9606 GN=RBM14 PE=1 SV=2 5.21 1700.2 - 623084 - - - -1.6592 - 2.38 0.408 - 319.8 1 2 0 -0.0019 10 0 0 0 5.11E+08 2.65E+08 - - - 5.6206 0.982 221125_WJC_METTL3_EV_vs_WT_F05.06558.06558.2 0.012 14-Aug R.TYDETYQR[166.11].Y "sp|O14974|MYPT1_HUMAN,tr|H0YHI8|H0YHI8_HUMAN,tr|H0YIS3|H0YIS3_HUMAN,tr|H0YIL7|H0YIL7_HUMAN" 4 1084.4701 0.92 59870 6558 2 1084.464517 543.2423 Protein phosphatase 1 regulatory subunit 12A OS=Homo sapiens OX=9606 GN=PPP1R12A PE=1 SV=1 4.37 1701.1 - 441904 - - - -5.1242 - 1.158 0.408 - 220.4 1 2 0 -0.0056 8 0 0 0 8.51E+06 9.28E+06 - - - 2.4952 0.9987 221125_WJC_METTL3_EV_vs_WT_F05.06559.06559.2 0.0553 16-Aug K.LYC[160.03]NVDSNK.Q sp|Q01780|EXOSX_HUMAN 1 1111.4968 1.09 59871 6559 2 1111.495469 556.7557 Exosome component 10 OS=Homo sapiens OX=9606 GN=EXOSC10 PE=1 SV=2 5.83 1701.2 - 245772 - - - -1.2056 - 1.462 0.307 - 154.7 1 2 0 -0.0013 9 0 0 0 1.07E+07 9.79E+06 - - - 2.4069 1 221125_WJC_METTL3_EV_vs_WT_F05.06563.06563.3 1.12E-05 Dec-36 R.LPDAHSDYAR.Y sp|Q96PK6|RBM14_HUMAN 1 1143.5309 1.93 59873 6563 3 1143.529292 382.1842 RNA-binding protein 14 OS=Homo sapiens OX=9606 GN=RBM14 PE=1 SV=2 5.21 1701.7 - 2.78E+06 - - - -1.3939 - 2.175 0.544 - 247.2 1 2 0 -0.0016 10 0 0 0 5.11E+08 2.65E+08 - - - 6.8739 0.9998 221125_WJC_METTL3_EV_vs_WT_F05.06567.06567.2 2.94E-06 18-Aug R.GC[160.03]VNYEGADR[166.11].V "sp|Q7Z5L9|I2BP2_HUMAN,sp|Q9H1B7|I2BPL_HUMAN" 2 1149.4748 1.5 59875 6567 2 1149.474128 575.7447 Interferon regulatory factor 2-binding protein 2 OS=Homo sapiens OX=9606 GN=IRF2BP2 PE=1 SV=2 4.37 1702.1 - 750268 - - - -0.6212 - 1.921 0.451 - 260.3 1 2 0 -0.0007 10 0 0 0 2.50E+07 1.66E+07 - - - 4.1942 0.9993 221125_WJC_METTL3_EV_vs_WT_F05.06572.06572.2 0.00421 14-Oct R.TQNVLGEK[136.11].G "sp|P23396|RS3_HUMAN,tr|E9PL09|E9PL09_HUMAN,tr|E9PK82|E9PK82_HUMAN,tr|F2Z2S8|F2Z2S8_HUMAN,tr|H0YCJ7|H0YCJ7_HUMAN,tr|E9PQ96|E9PQ96_HUMAN,tr|E9PJH4|E9PJH4_HUMAN,tr|E9PPU1|E9PPU1_HUMAN,tr|H0YF32|H0YF32_HUMAN" 9 895.4854 0.69 59878 6572 2 895.484383 448.75 40S ribosomal protein S3 OS=Homo sapiens OX=9606 GN=RPS3 PE=1 SV=2 5.66 1702.7 - 5.44E+06 - - - -1.1871 - 1.572 0.339 - 473.8 1 2 0 -0.0011 8 0 0 0 6.34E+08 9.17E+08 - - - 2.9088 0.9993 221125_WJC_METTL3_EV_vs_WT_F05.06574.06574.2 1.39E-07 22-Dec R.TYGEPESAGPSR[166.11].A "sp|P50402|EMD_HUMAN,tr|A0A804HIV7|A0A804HIV7_HUMAN,tr|Q5HY57|Q5HY57_HUMAN" 3 1259.5658 1.5 59880 6574 2 1259.560802 630.7902 Emerin OS=Homo sapiens OX=9606 GN=EMD PE=1 SV=1 4.53 1702.9 - 332088 - - - -3.9402 - 2.196 0.623 - 345.4 1 2 0 -0.005 12 0 0 0 1.54E+07 1.03E+07 - - - 5.7107 0.9996 221125_WJC_METTL3_EV_vs_WT_F05.06580.06580.2 0.00193 12-Jul K.YYLHDDR.E "sp|Q9Y2W1|TR150_HUMAN,tr|A0A3B3ITZ9|A0A3B3ITZ9_HUMAN" 2 980.4352 2.52 59884 6580 2 980.435168 491.2249 Thyroid hormone receptor-associated protein 3 OS=Homo sapiens OX=9606 GN=THRAP3 PE=1 SV=2 5.21 1703.6 - 1.44E+07 - - - -0.0275 - 1.446 0.425 - 230.9 1 2 0 0 7 0 0 0 1.07E+09 4.24E+08 - - - 3.3486 0.9996 221125_WJC_METTL3_EV_vs_WT_F05.06581.06581.2 0.00438 12-Jun K.YYLHDDR[166.11].E "sp|Q9Y2W1|TR150_HUMAN,tr|A0A3B3ITZ9|A0A3B3ITZ9_HUMAN" 2 990.4435 2.5 59885 6581 2 990.443304 496.229 Thyroid hormone receptor-associated protein 3 OS=Homo sapiens OX=9606 GN=THRAP3 PE=1 SV=2 5.21 1703.6 - 7.42E+06 - - - -0.1626 - 1.419 0.408 - 137.8 1 2 0 -0.0002 7 0 0 0 1.07E+09 4.28E+08 - - - 3.1633 0.9888 221125_WJC_METTL3_EV_vs_WT_F05.06582.06582.2 1.64 12-Jul R.R[166.11]LDQLER[166.11].K "sp|Q96CT7|CC124_HUMAN,tr|M0R2F5|M0R2F5_HUMAN" 2 948.5256 0.64 59886 6582 2 948.52618 475.2701 Coiled-coil domain-containing protein 124 OS=Homo sapiens OX=9606 GN=CCDC124 PE=1 SV=1 6.07 1703.7 - 4.13E+06 - - - 0.6442 - 1.479 0.066 - 149 2 2 0 0.0006 7 0 0 0 1.03E+08 1.61E+08 - - - 0.6339 0.9971 221125_WJC_METTL3_EV_vs_WT_F05.06583.06583.2 0.421 12-Sep R.RLDQLER.K "sp|Q96CT7|CC124_HUMAN,tr|M0R2F5|M0R2F5_HUMAN" 2 928.509 0.66 59887 6583 2 928.508849 465.2618 Coiled-coil domain-containing protein 124 OS=Homo sapiens OX=9606 GN=CCDC124 PE=1 SV=1 6.07 1703.7 - 2.85E+06 - - - -0.1939 - 1.96 0.043 - 287.7 1 2 0 -0.0002 7 0 0 0 1.02E+08 1.55E+08 - - - 1.4908 0.9995 221125_WJC_METTL3_EV_vs_WT_F05.06584.06584.2 0.0557 18-Nov R.SITNTTVC[160.03]TK[136.11].C "sp|Q15637|SF01_HUMAN,tr|A0A7P0T9U7|A0A7P0T9U7_HUMAN" 2 1131.5685 1.16 59888 6584 2 1131.568443 566.7915 Splicing factor 1 OS=Homo sapiens OX=9606 GN=SF1 PE=1 SV=4 7.94 1703.8 - 2.50E+06 - - - -0.0716 - 1.954 0.282 - 341.2 1 2 0 -0.0001 10 0 0 0 1.28E+08 1.10E+08 - - - 2.9937 0.9816 221125_WJC_METTL3_EV_vs_WT_F05.06585.06585.3 5.88E-05 13/36 E.LATDPELEK[136.11]K[136.11].L "sp|Q86U44|MTA70_HUMAN,tr|B4E349|B4E349_HUMAN,tr|F5H6D8|F5H6D8_HUMAN,tr|H0YFV6|H0YFV6_HUMAN,tr|B4DTN4|B4DTN4_HUMAN" 5 1158.6467 0.01 59889 6585 3 1158.643243 387.2228 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 4.68 1703.8 - 2.11E+06 - - - -2.9871 - 2.665 0.408 - 203.5 1 1 0 -0.0035 10 0 0 0 3.55E+06 3.42E+08 - - - 5.9505 0.9812 221125_WJC_METTL3_EV_vs_WT_F05.06592.06592.2 0.0297 14-Jun K.APGFGDNR.K "sp|P10809|CH60_HUMAN,tr|A0A7I2V2X6|A0A7I2V2X6_HUMAN,tr|A0A7I2YQK6|A0A7I2YQK6_HUMAN,tr|A0A7I2V599|A0A7I2V599_HUMAN,tr|A0A7I2V5M1|A0A7I2V5M1_HUMAN" 5 832.3828 1.47 59894 6592 2 832.38224 417.1987 "60 kDa heat shock protein, mitochondrial OS=Homo sapiens OX=9606 GN=HSPD1 PE=1 SV=2" 5.88 1704.7 - 1.90E+06 - - - -0.6307 - 1.277 0.062 - 131.4 1 2 0 -0.0005 8 0 0 0 1.66E+08 1.13E+08 - - - 0.2362 0.9833 221125_WJC_METTL3_EV_vs_WT_F05.06593.06593.2 1.58 12-Jun K.EQSIVEK[136.11].F "sp|Q86U44|MTA70_HUMAN,tr|H0YFV6|H0YFV6_HUMAN" 2 839.448 0.03 59895 6593 2 839.447244 420.7313 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 4.53 1704.7 - 1.81E+06 - - - -0.8982 - 1.322 0.06 - 205.7 1 2 0 -0.0008 7 0 0 0 2.08E+06 6.56E+07 - - - 0.3684 0.9996 221125_WJC_METTL3_EV_vs_WT_F05.06595.06595.2 0.00026 18-Dec R.LPDAHSDYAR.Y sp|Q96PK6|RBM14_HUMAN 1 1143.5309 1.65 59897 6595 2 1143.533244 572.7727 RNA-binding protein 14 OS=Homo sapiens OX=9606 GN=RBM14 PE=1 SV=2 5.21 1704.9 - 710766 - - - 2.062 - 1.986 0.47 - 350.1 1 2 0 0.0024 10 0 0 0 5.46E+07 3.31E+07 - - - 4.4269 0.9996 221125_WJC_METTL3_EV_vs_WT_F05.06596.06596.2 0.03 14-Aug K.VNVPEESR[166.11].N sp|Q9UEY8|ADDG_HUMAN 1 938.4697 1.39 59898 6596 2 938.469141 470.2421 Gamma-adducin OS=Homo sapiens OX=9606 GN=ADD3 PE=1 SV=1 4.53 1705.1 - 568482 - - - -0.5743 - 1.688 0.358 - 294.3 1 2 0 -0.0005 8 0 0 0 1.35E+07 9.75E+06 - - - 3.264 0.9999 221125_WJC_METTL3_EV_vs_WT_F05.06598.06598.2 0.000119 22-Dec R.TYGEPESAGPSR.A "sp|P50402|EMD_HUMAN,tr|A0A804HIV7|A0A804HIV7_HUMAN,tr|Q5HY57|Q5HY57_HUMAN" 3 1249.5575 1.5 59900 6598 2 1249.558075 625.786 Emerin OS=Homo sapiens OX=9606 GN=EMD PE=1 SV=1 4.53 1705.3 - 529958 - - - 0.4642 - 2.149 0.569 - 364.7 1 2 0 0.0006 12 0 0 0 1.54E+07 1.03E+07 - - - 5.2563 0.9886 221125_WJC_METTL3_EV_vs_WT_F05.06601.06601.2 1.01 14-Jul R.GWGTQDSR.L "sp|Q9UPQ9|TNR6B_HUMAN,tr|H0Y720|H0Y720_HUMAN" 2 905.3991 2.44 59901 6601 2 905.397734 453.7068 Trinucleotide repeat-containing gene 6B protein OS=Homo sapiens OX=9606 GN=TNRC6B PE=1 SV=4 5.84 1705.8 - 862687 - - - -1.5573 - 1.457 0.092 - 270.6 1 2 0 -0.0014 8 0 0 0 1.70E+07 6.98E+06 - - - 0.8552 0.9941 221125_WJC_METTL3_EV_vs_WT_F05.06602.06602.2 6.82E-05 16-Nov L.PDAHSDYAR.Y sp|Q96PK6|RBM14_HUMAN 1 1030.4468 2.41 59902 6602 2 1030.447183 516.2307 RNA-binding protein 14 OS=Homo sapiens OX=9606 GN=RBM14 PE=1 SV=2 5.22 1705.8 - 1.24E+06 - - - 0.3503 - 2.215 0.542 - 716.7 1 1 0 0.0004 9 0 0 0 5.98E+07 2.48E+07 - - - 5.3448 0.9984 221125_WJC_METTL3_EV_vs_WT_F05.06606.06606.2 0.145 18-Jul K.GELESSDQVR.E "sp|Q9P2E9|RRBP1_HUMAN,tr|A0A087WU26|A0A087WU26_HUMAN,tr|A0A087WVV2|A0A087WVV2_HUMAN,tr|F8W7S5|F8W7S5_HUMAN" 4 1118.5204 0.27 59904 6606 2 1118.522173 560.2675 Ribosome-binding protein 1 OS=Homo sapiens OX=9606 GN=RRBP1 PE=1 SV=5 4.14 1706.3 - 250095 - - - 1.6021 - 1.719 0.264 - 153.6 1 2 0 0.0018 10 0 0 0 1.76E+07 6.42E+07 - - - 2.5025 0.9902 221125_WJC_METTL3_EV_vs_WT_F05.06614.06614.2 0.000186 18-Oct E.LATDPELEK[136.11]K[136.11].L "sp|Q86U44|MTA70_HUMAN,tr|B4E349|B4E349_HUMAN,tr|F5H6D8|F5H6D8_HUMAN,tr|H0YFV6|H0YFV6_HUMAN,tr|B4DTN4|B4DTN4_HUMAN" 5 1158.6467 0.01 59910 6614 2 1158.645982 580.3306 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 4.68 1707.2 - 1.32E+06 - - - -0.6231 - 2.015 0.466 - 317.4 1 1 0 -0.0007 10 0 0 0 3.96E+05 4.23E+07 - - - 4.4383 0.9383 221125_WJC_METTL3_EV_vs_WT_F05.06617.06617.2 5.12 12-Jun K.QSVELC[160.03]K.K "sp|Q00610|CLH1_HUMAN,sp|P53675|CLH2_HUMAN,tr|K7EJJ5|K7EJJ5_HUMAN,tr|J3KS13|J3KS13_HUMAN,tr|H0YGJ9|H0YGJ9_HUMAN,tr|A0A087WXH4|A0A087WXH4_HUMAN,tr|A0A087WVQ6|A0A087WVQ6_HUMAN,tr|J3KRF5|J3KRF5_HUMAN" 8 862.4219 0.53 59913 6617 2 862.422878 432.2182 Clathrin heavy chain 1 OS=Homo sapiens OX=9606 GN=CLTC PE=1 SV=5 5.99 1707.5 - 353104 - - - 1.1885 - 1.127 0.032 - 143.6 1 2 0 0.001 7 0 0 0 1.71E+07 3.24E+07 - - - -0.3441 0.9996 221125_WJC_METTL3_EV_vs_WT_F05.06624.06624.2 0.000844 16-Sep R.VADNSFDAK.R "sp|Q14978|NOLC1_HUMAN,tr|A0A0A0MRM9|A0A0A0MRM9_HUMAN" 2 965.4454 1.31 59917 6624 2 965.446079 483.73 Nucleolar and coiled-body phosphoprotein 1 OS=Homo sapiens OX=9606 GN=NOLC1 PE=1 SV=2 4.21 1708.4 - 1.50E+06 - - - 0.6774 - 1.511 0.429 - 245.8 1 2 0 0.0007 9 0 0 0 6.98E+07 5.32E+07 - - - 3.4036 0.9956 221125_WJC_METTL3_EV_vs_WT_F05.06631.06631.2 0.0355 16-Aug K.EGIPPDQQR[166.11].L "sp|P62979|RS27A_HUMAN,sp|P0CG48|UBC_HUMAN,sp|P0CG48|UBC_HUMAN,sp|P0CG48|UBC_HUMAN,sp|P0CG48|UBC_HUMAN,sp|P0CG48|UBC_HUMAN,sp|P0CG48|UBC_HUMAN,sp|P0CG48|UBC_HUMAN,sp|P0CG48|UBC_HUMAN,sp|P0CG48|UBC_HUMAN,sp|P0CG47|UBB_HUMAN,sp|P0CG47|UBB_HUMAN,sp|P0CG47|UBB_HUMAN,sp|P62987|RL40_HUMAN,tr|F5H388|F5H388_HUMAN,tr|F5H388|F5H388_HUMAN,tr|F5GYU3|F5GYU3_HUMAN,tr|F5GYU3|F5GYU3_HUMAN,tr|B4DV12|B4DV12_HUMAN,tr|B4DV12|B4DV12_HUMAN,tr|J3QSA3|J3QSA3_HUMAN,tr|Q5PY61|Q5PY61_HUMAN,tr|Q5PY61|Q5PY61_HUMAN,tr|Q5PY61|Q5PY61_HUMAN,tr|F5H2Z3|F5H2Z3_HUMAN,tr|F5H2Z3|F5H2Z3_HUMAN,tr|M0R2S1|M0R2S1_HUMAN,tr|J3QS39|J3QS39_HUMAN,tr|J3QTR3|J3QTR3_HUMAN,tr|Q96C32|Q96C32_HUMAN,tr|Q96C32|Q96C32_HUMAN,tr|Q96C32|Q96C32_HUMAN,tr|Q96C32|Q96C32_HUMAN,tr|M0R1V7|M0R1V7_HUMAN,tr|F5H747|F5H747_HUMAN,tr|F5H747|F5H747_HUMAN,tr|F5GXK7|F5GXK7_HUMAN,tr|F5GXK7|F5GXK7_HUMAN,tr|M0R1M6|M0R1M6_HUMAN,tr|F5H6Q2|F5H6Q2_HUMAN,tr|F5H6Q2|F5H6Q2_HUMAN,tr|F5GZ39|F5GZ39_HUMAN,tr|J3QKN0|J3QKN0_HUMAN,tr|J3QKN0|J3QKN0_HUMAN,tr|J3QKN0|J3QKN0_HUMAN,tr|F5H265|F5H265_HUMAN,tr|F5H265|F5H265_HUMAN,tr|A0A2R8Y422|A0A2R8Y422_HUMAN" 48 1048.5177 0.64 59921 6631 2 1048.517759 525.2661 Ubiquitin-40S ribosomal protein S27a OS=Homo sapiens OX=9606 GN=RPS27A PE=1 SV=2 4.37 1709.2 - 1.70E+06 - - - 0.0629 - 1.28 0.195 - 214.1 1 2 0 0.0001 9 0 0 0 4.35E+07 6.74E+07 - - - 1.1954 0.9998 221125_WJC_METTL3_EV_vs_WT_F05.06634.06634.2 0.000143 18-Sep R.ANTVTPAVGR.L sp|Q53HL2|BOREA_HUMAN 1 984.5352 1.67 59922 6634 2 984.536063 493.2749 Borealin OS=Homo sapiens OX=9606 GN=CDCA8 PE=1 SV=2 9.79 1709.6 - 2.28E+06 - - - 0.8329 - 2.069 0.459 - 284.5 1 2 0 0.0008 10 0 0 0 9.75E+07 5.83E+07 - - - 4.4604 0.9997 221125_WJC_METTL3_EV_vs_WT_F05.06635.06635.2 0.00988 20-Oct K.VTQVDGNSPVR[166.11].F "sp|P48444|COPD_HUMAN,tr|B0YIW6|B0YIW6_HUMAN" 2 1180.6076 1.67 59923 6635 2 1180.606037 591.3111 Coatomer subunit delta OS=Homo sapiens OX=9606 GN=ARCN1 PE=1 SV=1 5.81 1709.7 - 1.14E+06 - - - -1.2985 - 2.051 0.429 - 357.6 1 2 0 -0.0015 11 0 0 0 1.06E+08 6.33E+07 - - - 4.1524 0.9879 221125_WJC_METTL3_EV_vs_WT_F05.06636.06636.2 0.128 12-May K.EIELTHR[166.11].M sp|O43395|PRPF3_HUMAN 1 906.4799 1.66 59924 6636 2 906.478908 454.2472 U4\U6 small nuclear ribonucleoprotein Prp3 OS=Homo sapiens OX=9606 GN=PRPF3 PE=1 SV=2 5.4 1709.8 - 921480 - - - -1.0392 - 1.192 0.157 - 137.5 2 2 0 -0.0009 7 0 0 0 1.28E+08 7.70E+07 - - - 0.6223 0.9141 221125_WJC_METTL3_EV_vs_WT_F05.06639.06639.2 1.63 16-Jul K.NNILNLQGK.G sp|P0C7X5|ZN806_HUMAN 1 1012.5665 102.68 59925 6639 2 1012.568783 507.2905 Zinc finger protein 806 OS=Homo sapiens OX=9606 GN=ZNF806 PE=3 SV=1 8.75 1710.2 - 631428 - - - 2.2122 - 1.07 0.096 - 119.1 2 2 0 0.0022 9 0 0 0 2.06E+07 2.01E+05 - - - -0.1894 0.9592 221125_WJC_METTL3_EV_vs_WT_F05.06640.06640.2 0.00588 16-Aug R.FDSPESAEK[136.11].A "sp|Q9P2K5|MYEF2_HUMAN,tr|A0A0A0MR39|A0A0A0MR39_HUMAN,tr|A0A0C4DGV1|A0A0C4DGV1_HUMAN,tr|A0A087WUT0|A0A087WUT0_HUMAN,tr|H0YKS1|H0YKS1_HUMAN,tr|A0A0A0MQW0|A0A0A0MQW0_HUMAN" 6 1016.4542 1.08 59926 6640 2 1016.448159 509.2344 Myelin expression factor 2 OS=Homo sapiens OX=9606 GN=MYEF2 PE=1 SV=3 4.14 1710.3 - 566422 - - - -5.9491 - 1.491 0.28 - 168.2 1 2 0 -0.006 9 0 0 0 2.83E+07 2.63E+07 - - - 2.2628 0.9977 221125_WJC_METTL3_EV_vs_WT_F05.06654.06654.2 0.0252 14-Aug R.QAFPNTNR[166.11].W sp|P26641|EF1G_HUMAN 1 956.4703 1.45 59933 6654 2 956.46817 479.2425 Elongation factor 1-gamma OS=Homo sapiens OX=9606 GN=EEF1G PE=1 SV=3 9.75 1712 - 1.15E+06 - - - -2.2771 - 1.415 0.325 - 265.6 1 2 0 -0.0022 8 0 0 0 9.71E+07 6.69E+07 - - - 2.4877 0.9997 221125_WJC_METTL3_EV_vs_WT_F05.06658.06658.2 0.000311 22-Sep R.LLQQGTAPAQAK.A sp|Q86YP4|P66A_HUMAN 1 1224.6826 1.51 59935 6658 2 1224.681901 613.3486 Transcriptional repressor p66-alpha OS=Homo sapiens OX=9606 GN=GATAD2A PE=1 SV=1 8.75 1712.6 - 356454 - - - -0.6002 - 1.768 0.417 - 254.3 1 2 0 -0.0007 12 0 0 0 9.22E+07 6.08E+07 - - - 3.6201 0.9237 221125_WJC_METTL3_EV_vs_WT_F05.06662.06662.3 0.145 Aug-36 R.YLHDESGLNR.R "sp|Q15019|SEPT2_HUMAN,tr|C9IY94|C9IY94_HUMAN,tr|C9JB25|C9JB25_HUMAN,tr|H7C310|H7C310_HUMAN,tr|C9J938|C9J938_HUMAN,tr|B5MCX3|B5MCX3_HUMAN,tr|C9J2Q4|C9J2Q4_HUMAN" 7 1202.568 1.06 59938 6662 3 1202.56857 401.8633 Septin-2 OS=Homo sapiens OX=9606 GN=SEPTIN2 PE=1 SV=1 5.32 1713.1 - 301028 - - - 0.474 - 1.356 0.138 - 42.1 6 2 0 0.0006 10 0 0 0 6.95E+06 6.56E+06 - - - 0.6076 0.9998 221125_WJC_METTL3_EV_vs_WT_F05.06665.06665.2 0.00365 18-Dec R.SPAAEC[160.03]LSEK.E "sp|Q12931|TRAP1_HUMAN,tr|I3L0K7|I3L0K7_HUMAN" 2 1090.4965 1.47 59939 6665 2 1090.49756 546.2555 "Heat shock protein 75 kDa, mitochondrial OS=Homo sapiens OX=9606 GN=TRAP1 PE=1 SV=3" 4.53 1713.4 - 795788 - - - 0.995 - 2.247 0.47 - 732.7 1 2 0 0.0011 10 0 0 0 3.05E+07 2.07E+07 - - - 4.7719 0.9998 221125_WJC_METTL3_EV_vs_WT_F05.06671.06671.2 2.76E-06 22-Nov R.LLQQGTAPAQAK[136.11].A sp|Q86YP4|P66A_HUMAN 1 1232.6968 1.51 59943 6671 2 1232.697903 617.3557 Transcriptional repressor p66-alpha OS=Homo sapiens OX=9606 GN=GATAD2A PE=1 SV=1 8.75 1714.2 - 755860 - - - 0.8656 - 1.906 0.468 - 409.5 1 2 0 0.0011 12 0 0 0 9.21E+07 6.08E+07 - - - 4.1944 0.9852 221125_WJC_METTL3_EV_vs_WT_F05.06675.06675.2 0.0633 14-Aug R.YREPPALK.S "sp|Q92615|LAR4B_HUMAN,tr|A0A087X183|A0A087X183_HUMAN,tr|H0Y4V9|H0Y4V9_HUMAN" 3 972.5393 1.31 59945 6675 2 972.538128 487.2769 La-related protein 4B OS=Homo sapiens OX=9606 GN=LARP4B PE=1 SV=3 8.59 1714.7 - 516755 - - - -1.1701 - 1.595 0.256 - 205.9 1 2 1 -0.0011 8 0 0 0 8.04E+07 6.16E+07 - - - 2.3395 0.9974 221125_WJC_METTL3_EV_vs_WT_F05.06677.06677.2 0.101 18-Jun R.SHPLPETAVR[166.11].G sp|Q9HCS7|SYF1_HUMAN 1 1115.5963 0.77 59947 6677 2 1115.595613 558.8054 Pre-mRNA-splicing factor SYF1 OS=Homo sapiens OX=9606 GN=XAB2 PE=1 SV=2 6.47 1715 - 353159 - - - -0.5952 - 1.257 0.264 - 130.9 1 2 0 -0.0007 10 0 0 0 5.38E+06 6.98E+06 - - - 1.6291 0.9984 221125_WJC_METTL3_EV_vs_WT_F05.06680.06680.2 0.48 16-Sep K.DTDSEEEIR[166.11].E "sp|P0DP25|CALM3_HUMAN,sp|P0DP23|CALM1_HUMAN,sp|P0DP24|CALM2_HUMAN,tr|G3V361|G3V361_HUMAN,tr|A0A590UJI2|A0A590UJI2_HUMAN,tr|Q96HY3|Q96HY3_HUMAN,tr|A0A590UJC0|A0A590UJC0_HUMAN,tr|G3V226|G3V226_HUMAN,tr|E7EMB3|E7EMB3_HUMAN" 9 1102.4654 0.14 59948 6680 2 1102.466912 552.24 Calmodulin-3 OS=Homo sapiens OX=9606 GN=CALM3 PE=1 SV=1 3.83 1715.5 - 1.18E+06 - - - 1.3878 - 1.735 0.235 - 405.1 1 2 0 0.0015 9 0 0 0 8.36E+06 5.87E+07 - - - 2.3703 0.9997 221125_WJC_METTL3_EV_vs_WT_F05.06681.06681.2 4.46E-05 20-Oct K.ENAGEDPGLAR.Q sp|P81605|DCD_HUMAN 1 1127.5207 1195.47 59949 6681 2 1127.52279 564.7676 Dermcidin OS=Homo sapiens OX=9606 GN=DCD PE=1 SV=2 4.14 1715.6 - 492824 - - - 1.8394 - 2.151 0.507 - 258.2 1 2 0 0.0021 11 0 0 0 5.06E+09 4.23E+06 - - - 4.8571 0.9891 221125_WJC_METTL3_EV_vs_WT_F05.06682.06682.2 0.254 14-Jul K.DVPNNQLR[166.11].H "sp|Q9BYJ9|YTHD1_HUMAN,sp|Q7Z739|YTHD3_HUMAN,tr|A0A087X0Q1|A0A087X0Q1_HUMAN,tr|A0A024R7W5|A0A024R7W5_HUMAN,tr|A0A087WY31|A0A087WY31_HUMAN" 5 964.4966 2.29 59950 6682 2 964.498484 483.2556 YTH domain-containing family protein 1 OS=Homo sapiens OX=9606 GN=YTHDF1 PE=1 SV=1 5.84 1715.7 - 745794 - - - 1.9917 - 1.196 0.211 - 204.9 1 2 0 0.0019 8 0 0 0 5.82E+07 2.54E+07 - - - 1.1386 0.9997 221125_WJC_METTL3_EV_vs_WT_F05.06683.06683.2 9.32E-06 20-Nov K.IATC[160.03]SDDNTLK[136.11].L "sp|Q9NZJ0|DTL_HUMAN,tr|F5GZ90|F5GZ90_HUMAN" 2 1244.5798 0.97 59951 6683 2 1244.577117 623.2972 Denticleless protein homolog OS=Homo sapiens OX=9606 GN=DTL PE=1 SV=3 4.21 1715.8 - 267828 - - - -2.1694 - 2.338 0.504 - 380.8 1 2 0 -0.0027 11 0 0 0 8.04E+06 8.32E+06 - - - 5.0602 0.9528 221125_WJC_METTL3_EV_vs_WT_F05.06684.06684.2 0.648 18-Jun K.AAQSANISVR[166.11].G sp|P35914|HMGCL_HUMAN 1 1025.5493 0.72 59952 6684 2 1025.550565 513.7819 "Hydroxymethylglutaryl-CoA lyase, mitochondrial OS=Homo sapiens OX=9606 GN=HMGCL PE=1 SV=2" 9.79 1716 - 242075 - - - 1.2072 - 1.246 0.096 - 109 15 2 0 0.0012 10 0 0 0 5.06E+06 7.01E+06 - - - -0.1618 0.9984 221125_WJC_METTL3_EV_vs_WT_F05.06688.06688.2 0.0477 16-Sep R.FDSPESAEK.A "sp|Q9P2K5|MYEF2_HUMAN,tr|A0A0A0MR39|A0A0A0MR39_HUMAN,tr|A0A0C4DGV1|A0A0C4DGV1_HUMAN,tr|A0A087WUT0|A0A087WUT0_HUMAN,tr|H0YKS1|H0YKS1_HUMAN,tr|A0A0A0MQW0|A0A0A0MQW0_HUMAN" 6 1008.44 1.07 59954 6688 2 1008.440296 505.2273 Myelin expression factor 2 OS=Homo sapiens OX=9606 GN=MYEF2 PE=1 SV=3 4.14 1716.5 - 1.04E+06 - - - 0.2876 - 1.664 0.202 - 221 1 2 0 0.0003 9 0 0 0 3.15E+07 2.95E+07 - - - 2.0061 0.9979 221125_WJC_METTL3_EV_vs_WT_F05.06689.06689.2 0.358 16-Aug R.C[160.03]EASNIVGK[136.11].A "sp|Q9BY67|CADM1_HUMAN,tr|X5DQS5|X5DQS5_HUMAN,tr|A0A087X0T8|A0A087X0T8_HUMAN,tr|A0A087X1W8|A0A087X1W8_HUMAN,tr|A0A0A0MTJ8|A0A0A0MTJ8_HUMAN" 5 984.479 1.99 59955 6689 2 984.478886 493.2468 Cell adhesion molecule 1 OS=Homo sapiens OX=9606 GN=CADM1 PE=1 SV=2 5.99 1716.6 - 1.03E+06 - - - -0.0965 - 1.386 0.236 - 254.4 1 2 0 -0.0001 9 0 0 0 3.12E+07 1.57E+07 - - - 1.7284 0.993 221125_WJC_METTL3_EV_vs_WT_F05.06690.06690.2 0.0147 16-Oct R.LK[136.11]EELEEAR[166.11].D "sp|Q04637|IF4G1_HUMAN,tr|E7EUU4|E7EUU4_HUMAN,tr|E9PGM1|E9PGM1_HUMAN,tr|C9J6B6|C9J6B6_HUMAN,tr|E7EX73|E7EX73_HUMAN,tr|A0A7I2Y1C3|A0A7I2Y1C3_HUMAN,tr|C9JF13|C9JF13_HUMAN" 7 1133.6047 0.86 59956 6690 2 1133.605782 567.8096 Eukaryotic translation initiation factor 4 gamma 1 OS=Homo sapiens OX=9606 GN=EIF4G1 PE=1 SV=4 4.49 1716.7 - 374994 - - - 0.9342 - 1.759 0.321 - 279.5 1 2 1 0.0011 9 0 0 0 6.03E+06 6.99E+06 - - - 3.0454 0.9938 221125_WJC_METTL3_EV_vs_WT_F05.06693.06693.2 0.0138 18-Sep R.EVSDLQEEGK[136.11].N sp|Q9HBI1|PARVB_HUMAN 1 1140.539 0.78 59959 6693 2 1140.542269 571.2768 Beta-parvin OS=Homo sapiens OX=9606 GN=PARVB PE=1 SV=1 4 1717.1 - 192311 - - - 2.8679 - 1.557 0.238 - 210.1 1 2 0 0.0033 10 0 0 0 2.62E+06 3.34E+06 - - - 2.0337 0.9771 221125_WJC_METTL3_EV_vs_WT_F05.06694.06694.2 0.0482 22-Jul R.LGAAVAPEGNQK.K "sp|Q9NW81|DMAC2_HUMAN,tr|K7EIV4|K7EIV4_HUMAN,tr|M0R078|M0R078_HUMAN,tr|B4DFT4|B4DFT4_HUMAN,tr|K7ESN5|K7ESN5_HUMAN,tr|M0QZC4|M0QZC4_HUMAN" 6 1153.6091 0.93 59960 6694 2 1153.611482 577.8118 Distal membrane-arm assembly complex protein 2 OS=Homo sapiens OX=9606 GN=DMAC2 PE=1 SV=3 6 1717.2 - 152218 - - - 2.0328 - 1.471 0.078 - 141.5 1 2 0 0.0023 12 0 0 0 9.46E+06 1.02E+07 - - - 0.6319 0.9988 221125_WJC_METTL3_EV_vs_WT_F05.06699.06699.2 0.163 16-Aug R.QITAQQINK.L sp|Q92900|RENT1_HUMAN 1 1042.5771 0.9 59963 6699 2 1042.578549 522.2958 Regulator of nonsense transcripts 1 OS=Homo sapiens OX=9606 GN=UPF1 PE=1 SV=2 8.75 1717.8 - 2.82E+06 - - - 1.3822 - 1.641 0.291 - 147.5 1 2 0 0.0014 9 0 0 0 3.83E+07 4.26E+07 - - - 2.6228 0.9989 221125_WJC_METTL3_EV_vs_WT_F05.06700.06700.2 0.601 16-Aug K.DTDSEEEIR.E "sp|P0DP25|CALM3_HUMAN,sp|P0DP23|CALM1_HUMAN,sp|P0DP24|CALM2_HUMAN,tr|G3V361|G3V361_HUMAN,tr|A0A590UJI2|A0A590UJI2_HUMAN,tr|Q96HY3|Q96HY3_HUMAN,tr|A0A590UJC0|A0A590UJC0_HUMAN,tr|G3V226|G3V226_HUMAN,tr|E7EMB3|E7EMB3_HUMAN" 9 1092.4571 0.62 59964 6700 2 1092.458822 547.2358 Calmodulin-3 OS=Homo sapiens OX=9606 GN=CALM3 PE=1 SV=1 3.83 1717.8 - 2.35E+06 - - - 1.5653 - 1.814 0.275 - 334.1 1 2 0 0.0017 9 0 0 0 3.90E+07 6.29E+07 - - - 2.7945 0.9814 221125_WJC_METTL3_EV_vs_WT_F05.06701.06701.2 0.257 14-Jun K.SLSDTVEK.L "sp|Q14203|DCTN1_HUMAN,tr|A0A804CDA6|A0A804CDA6_HUMAN,tr|E7EX90|E7EX90_HUMAN,tr|A0A7P0Z4C3|A0A7P0Z4C3_HUMAN,tr|E7EWF7|E7EWF7_HUMAN" 5 877.4393 1.44 59965 6701 2 877.440056 439.7269 Dynactin subunit 1 OS=Homo sapiens OX=9606 GN=DCTN1 PE=1 SV=3 4.37 1717.9 - 1.06E+06 - - - 0.8878 - 1.002 0.177 - 88.4 1 2 0 0.0008 8 0 0 0 1.28E+07 8.85E+06 - - - 0.3541 0.9725 221125_WJC_METTL3_EV_vs_WT_F05.06703.06703.2 4.21 14-Jul K.SLSDTVEK[136.11].L "sp|Q14203|DCTN1_HUMAN,tr|A0A804CDA6|A0A804CDA6_HUMAN,tr|E7EX90|E7EX90_HUMAN,tr|A0A7P0Z4C3|A0A7P0Z4C3_HUMAN,tr|E7EWF7|E7EWF7_HUMAN" 5 885.4535 3.59 59967 6703 2 885.453887 443.734 Dynactin subunit 1 OS=Homo sapiens OX=9606 GN=DCTN1 PE=1 SV=3 4.37 1718.2 - 551219 - - - 0.463 - 1.094 0.093 - 105.4 1 2 0 0.0004 8 0 0 0 3.06E+07 8.52E+06 - - - -0.0013 0.9988 221125_WJC_METTL3_EV_vs_WT_F05.06704.06704.2 0.000163 20-Oct K.IATC[160.03]SDDNTLK.L "sp|Q9NZJ0|DTL_HUMAN,tr|F5GZ90|F5GZ90_HUMAN" 2 1236.5656 0.97 59968 6704 2 1236.570907 619.2901 Denticleless protein homolog OS=Homo sapiens OX=9606 GN=DTL PE=1 SV=3 4.21 1718.3 - 868913 - - - 4.278 - 2.163 0.546 - 239.5 1 2 0 0.0053 11 0 0 0 8.04E+06 8.32E+06 - - - 5.1592 0.9995 221125_WJC_METTL3_EV_vs_WT_F05.06709.06709.2 0.000219 26-Sep R.LAGDPSAGDGAAPR[166.11].V sp|Q96GD0|PLPP_HUMAN 1 1263.6083 1.41 59973 6709 2 1263.609571 632.8114 Chronophin OS=Homo sapiens OX=9606 GN=PDXP PE=1 SV=2 4.21 1718.9 - 96414.6 - - - 1.0066 - 1.935 0.365 - 211.3 1 2 0 0.0013 14 0 0 0 3.44E+06 2.44E+06 - - - 3.393 0.9971 221125_WJC_METTL3_EV_vs_WT_F05.06713.06713.2 0.107 16-Sep K.MPQVSQEAK[136.11].G sp|Q96T58|MINT_HUMAN 1 1024.5103 1.68 59975 6713 2 1024.511902 513.2624 Msx2-interacting protein OS=Homo sapiens OX=9606 GN=SPEN PE=1 SV=1 5.75 1719.5 - 448933 - - - 1.5822 - 1.453 0.251 - 126.9 1 2 0 0.0016 9 0 0 0 1.57E+07 9.37E+06 - - - 1.9753 0.9991 221125_WJC_METTL3_EV_vs_WT_F05.06715.06715.2 0.0249 14-Jul R.DNQFDSPK.R "sp|O14654|IRS4_HUMAN,tr|A0A804CF45|A0A804CF45_HUMAN" 2 949.4141 1.19 59977 6715 2 949.415179 475.7143 Insulin receptor substrate 4 OS=Homo sapiens OX=9606 GN=IRS4 PE=1 SV=1 4.21 1719.6 - 967544 - - - 1.1102 - 1.362 0.385 - 289.7 1 2 0 0.0011 8 0 0 0 5.58E+07 4.71E+07 - - - 2.8161 0.9971 221125_WJC_METTL3_EV_vs_WT_F05.06718.06718.3 0.00382 Sep-32 R.R[166.11]EPPPYGYR[166.11].K "sp|Q13573|SNW1_HUMAN,tr|G3V3A4|G3V3A4_HUMAN,tr|G3V5R3|G3V5R3_HUMAN" 3 1153.5783 0.001 59980 6718 3 1153.574353 385.5334 SNW domain-containing protein 1 OS=Homo sapiens OX=9606 GN=SNW1 PE=1 SV=1 8.59 1719.9 - 323138 - - - -3.4493 - 1.77 0.311 - 148.5 1 2 0 -0.004 9 0 0 0 0.00E+00 7.50E+06 - - - 3.7271 0.9294 221125_WJC_METTL3_EV_vs_WT_F05.06719.06719.2 7.1 18-May K.IQPYTEQSTK[136.11].M "sp|Q8IZA0|K319L_HUMAN,tr|E7EN73|E7EN73_HUMAN,tr|C9J519|C9J519_HUMAN" 3 1201.607 1.95 59981 6719 2 1201.606127 601.8108 Dyslexia-associated protein KIAA0319-like protein OS=Homo sapiens OX=9606 GN=KIAA0319L PE=1 SV=2 6 1720.1 - 144810 - - - -0.7415 - 1.24 0.017 - 57.9 7 2 0 -0.0009 10 0 0 0 4.11E+06 2.11E+06 - - - -0.6108 1 221125_WJC_METTL3_EV_vs_WT_F05.06724.06724.2 2.13E-06 14/22 R.MGHAGAIIAGGK.G sp|P53597|SUCA_HUMAN 1 1081.5702 1.3 59984 6724 2 1081.570616 541.7924 "Succinate--CoA ligase [ADP\GDP-forming] subunit alpha, mitochondrial OS=Homo sapiens OX=9606 GN=SUCLG1 PE=1 SV=4" 8.52 1720.7 - 811557 - - - 0.3393 - 2.636 0.599 - 607.6 1 2 0 0.0004 12 0 0 0 1.21E+07 9.31E+06 - - - 6.0154 0.9995 221125_WJC_METTL3_EV_vs_WT_F05.06725.06725.2 0.0028 16-Sep K.DSVLAGTNK.E "sp|Q6W2J9|BCOR_HUMAN,tr|H7BZ37|H7BZ37_HUMAN,tr|A1A564|A1A564_HUMAN,tr|H7C2V9|H7C2V9_HUMAN,tr|H7BYY2|H7BYY2_HUMAN,tr|H7C231|H7C231_HUMAN" 6 903.4662 0.6 59985 6725 2 903.465354 452.7404 BCL-6 corepressor OS=Homo sapiens OX=9606 GN=BCOR PE=1 SV=1 5.84 1720.9 - 479452 - - - -0.8932 - 1.707 0.354 - 294.4 1 2 0 -0.0008 9 0 0 0 4.08E+07 6.75E+07 - - - 3.2024 0.9816 221125_WJC_METTL3_EV_vs_WT_F05.06727.06727.2 1.34 16-Jul K.DSVLAGTNK[136.11].E "sp|Q6W2J9|BCOR_HUMAN,tr|H7BZ37|H7BZ37_HUMAN,tr|A1A564|A1A564_HUMAN,tr|H7C2V9|H7C2V9_HUMAN,tr|H7BYY2|H7BYY2_HUMAN,tr|H7C231|H7C231_HUMAN" 6 911.4804 0.58 59987 6727 2 911.479039 456.7475 BCL-6 corepressor OS=Homo sapiens OX=9606 GN=BCOR PE=1 SV=1 5.84 1721.1 - 446315 - - - -1.4504 - 1.172 0.133 - 132.2 1 2 0 -0.0013 9 0 0 0 4.25E+07 7.32E+07 - - - 0.4821 0.991 221125_WJC_METTL3_EV_vs_WT_F05.06728.06728.2 0.693 16-Jul K.KIEVPAQLK[136.11].E sp|Q8WYP5|ELYS_HUMAN 1 1032.6423 - 59988 6728 2 1032.64214 517.3284 Protein ELYS OS=Homo sapiens OX=9606 GN=AHCTF1 PE=1 SV=3 8.59 1721.2 - 395243 - - - -0.1365 - 1.608 0.055 - 200.5 2 2 0 -0.0001 9 0 0 0 - - - - - 0.6869 0.995 221125_WJC_METTL3_EV_vs_WT_F05.06729.06729.2 0.0232 26-Dec R.LAGDPSAGDGAAPR.V sp|Q96GD0|PLPP_HUMAN 1 1253.6 1.41 59989 6729 2 1253.603474 627.8073 Chronophin OS=Homo sapiens OX=9606 GN=PDXP PE=1 SV=2 4.21 1721.4 - 236848 - - - 2.7481 - 1.373 0.312 - 61.7 1 2 0 0.0034 14 0 0 0 3.44E+06 2.44E+06 - - - 2.1398 0.7823 221125_WJC_METTL3_EV_vs_WT_F05.06732.06732.2 1.19 14-Jul R.YR[166.11]EPPALK[136.11].S "sp|Q92615|LAR4B_HUMAN,tr|A0A087X183|A0A087X183_HUMAN,tr|H0Y4V9|H0Y4V9_HUMAN" 3 990.5617 1.31 59991 6732 2 990.56242 496.2881 La-related protein 4B OS=Homo sapiens OX=9606 GN=LARP4B PE=1 SV=3 8.59 1721.7 - 3.21E+06 - - - 0.6905 - 1.559 0.013 - 161.5 6 2 1 0.0007 8 0 0 0 8.12E+07 6.21E+07 - - - 0.1284 0.9715 221125_WJC_METTL3_EV_vs_WT_F05.06735.06735.2 0.000391 14-Jul L.GHPAPNFK[136.11].A "sp|Q06830|PRDX1_HUMAN,tr|A0A0A0MRQ5|A0A0A0MRQ5_HUMAN,tr|A0A0A0MSI0|A0A0A0MSI0_HUMAN" 3 874.4541 1.04 59993 6735 2 874.452969 438.2343 Peroxiredoxin-1 OS=Homo sapiens OX=9606 GN=PRDX1 PE=1 SV=1 8.76 1722 - 2.41E+06 - - - -1.2774 - 1.453 0.435 - 187.1 1 1 0 -0.0011 8 0 0 0 1.84E+08 1.78E+08 - - - 3.3804 0.991 221125_WJC_METTL3_EV_vs_WT_F05.06737.06737.2 0.249 16-Jul K.EGIPPDQQR.L "sp|P62979|RS27A_HUMAN,sp|P0CG48|UBC_HUMAN,sp|P0CG48|UBC_HUMAN,sp|P0CG48|UBC_HUMAN,sp|P0CG48|UBC_HUMAN,sp|P0CG48|UBC_HUMAN,sp|P0CG48|UBC_HUMAN,sp|P0CG48|UBC_HUMAN,sp|P0CG48|UBC_HUMAN,sp|P0CG48|UBC_HUMAN,sp|P0CG47|UBB_HUMAN,sp|P0CG47|UBB_HUMAN,sp|P0CG47|UBB_HUMAN,sp|P62987|RL40_HUMAN,tr|F5H388|F5H388_HUMAN,tr|F5H388|F5H388_HUMAN,tr|F5GYU3|F5GYU3_HUMAN,tr|F5GYU3|F5GYU3_HUMAN,tr|B4DV12|B4DV12_HUMAN,tr|B4DV12|B4DV12_HUMAN,tr|J3QSA3|J3QSA3_HUMAN,tr|Q5PY61|Q5PY61_HUMAN,tr|Q5PY61|Q5PY61_HUMAN,tr|Q5PY61|Q5PY61_HUMAN,tr|F5H2Z3|F5H2Z3_HUMAN,tr|F5H2Z3|F5H2Z3_HUMAN,tr|M0R2S1|M0R2S1_HUMAN,tr|J3QS39|J3QS39_HUMAN,tr|J3QTR3|J3QTR3_HUMAN,tr|Q96C32|Q96C32_HUMAN,tr|Q96C32|Q96C32_HUMAN,tr|Q96C32|Q96C32_HUMAN,tr|Q96C32|Q96C32_HUMAN,tr|M0R1V7|M0R1V7_HUMAN,tr|F5H747|F5H747_HUMAN,tr|F5H747|F5H747_HUMAN,tr|F5GXK7|F5GXK7_HUMAN,tr|F5GXK7|F5GXK7_HUMAN,tr|M0R1M6|M0R1M6_HUMAN,tr|F5H6Q2|F5H6Q2_HUMAN,tr|F5H6Q2|F5H6Q2_HUMAN,tr|F5GZ39|F5GZ39_HUMAN,tr|J3QKN0|J3QKN0_HUMAN,tr|J3QKN0|J3QKN0_HUMAN,tr|J3QKN0|J3QKN0_HUMAN,tr|F5H265|F5H265_HUMAN,tr|F5H265|F5H265_HUMAN,tr|A0A2R8Y422|A0A2R8Y422_HUMAN" 48 1038.5094 0.67 59995 6737 2 1038.512476 520.262 Ubiquitin-40S ribosomal protein S27a OS=Homo sapiens OX=9606 GN=RPS27A PE=1 SV=2 4.37 1722.1 - 2.22E+06 - - - 2.9398 - 1.431 0.247 - 144.8 2 2 0 0.0031 9 0 0 0 6.42E+07 9.61E+07 - - - 1.7667 0.9995 221125_WJC_METTL3_EV_vs_WT_F05.06738.06738.2 0.00972 14-Aug R.DNQFDSPK[136.11].R "sp|O14654|IRS4_HUMAN,tr|A0A804CF45|A0A804CF45_HUMAN" 2 957.4283 1.19 59996 6738 2 957.427824 479.7214 Insulin receptor substrate 4 OS=Homo sapiens OX=9606 GN=IRS4 PE=1 SV=1 4.21 1722.2 - 1.79E+06 - - - -0.5233 - 1.508 0.383 - 296.3 1 2 0 -0.0005 8 0 0 0 5.58E+07 4.71E+07 - - - 3.1086 0.9996 221125_WJC_METTL3_EV_vs_WT_F05.06739.06739.2 0.000318 16-Oct K.IGHPAPNFK.A "sp|Q06830|PRDX1_HUMAN,tr|A0A0A0MRQ5|A0A0A0MRQ5_HUMAN,tr|A0A0A0MSI0|A0A0A0MSI0_HUMAN" 3 979.524 0.75 59997 6739 2 979.523556 490.7693 Peroxiredoxin-1 OS=Homo sapiens OX=9606 GN=PRDX1 PE=1 SV=1 8.76 1722.3 - 1.32E+06 - - - -0.4022 - 1.629 0.368 - 283.1 1 2 0 -0.0004 9 0 0 0 1.28E+08 1.72E+08 - - - 3.1706 0.9981 221125_WJC_METTL3_EV_vs_WT_F05.06746.06746.2 0.524 14-Sep K.R[166.11]LEELEAK[136.11].R "sp|O60841|IF2P_HUMAN,tr|A0A087WUT6|A0A087WUT6_HUMAN" 2 1004.5621 4.86 60002 6746 2 1004.560982 503.2883 Eukaryotic translation initiation factor 5B OS=Homo sapiens OX=9606 GN=EIF5B PE=1 SV=4 4.79 1723.1 - 1.55E+06 - - - -1.1428 - 1.995 0.12 - 441.7 1 2 0 -0.0011 8 0 0 0 9.32E+07 1.92E+07 - - - 2.0099 0.9968 221125_WJC_METTL3_EV_vs_WT_F05.06748.06748.2 0.00342 16-Sep R.SQVEPADYK[136.11].A "sp|P48739|PIPNB_HUMAN,tr|B3KYB7|B3KYB7_HUMAN,tr|A0A0A0MSW4|A0A0A0MSW4_HUMAN,tr|B3KYB6|B3KYB6_HUMAN" 4 1043.5015 1.11 60004 6748 2 1043.504598 522.758 Phosphatidylinositol transfer protein beta isoform OS=Homo sapiens OX=9606 GN=PITPNB PE=1 SV=2 4.37 1723.3 - 711704 - - - 2.9784 - 1.531 0.325 - 379.8 1 2 0 0.0031 9 0 0 0 9.84E+06 8.86E+06 - - - 2.6727 0.9994 221125_WJC_METTL3_EV_vs_WT_F05.06755.06755.2 0.0243 14-Sep R.QVQNLVNK.S sp|P15924|DESP_HUMAN 1 941.5294 21.97 60009 6755 2 941.528138 471.772 Desmoplakin OS=Homo sapiens OX=9606 GN=DSP PE=1 SV=3 8.75 1724.1 - 4.52E+06 - - - -1.3722 - 1.702 0.353 - 430.1 1 2 0 -0.0013 8 0 0 0 2.85E+08 1.30E+07 - - - 3.2517 0.9996 221125_WJC_METTL3_EV_vs_WT_F05.06756.06756.2 0.000409 18-Aug R.TAYGPNGMNK.M "sp|P50990|TCPQ_HUMAN,tr|H7C4C8|H7C4C8_HUMAN" 2 1051.4757 0.08 60010 6756 2 1051.474314 526.7451 T-complex protein 1 subunit theta OS=Homo sapiens OX=9606 GN=CCT8 PE=1 SV=4 8.26 1724.1 - 6.81E+06 - - - -1.2991 - 1.692 0.434 - 165.4 1 2 0 -0.0014 10 0 0 0 1.53E+08 1.98E+09 - - - 3.7141 0.9652 221125_WJC_METTL3_EV_vs_WT_F05.06759.06759.2 0.000883 18-Aug E.YVLKPATEGK.R "sp|Q5T2N8|ATD3C_HUMAN,sp|Q9NVI7|ATD3A_HUMAN,tr|Q5SV16|Q5SV16_HUMAN" 3 1104.6179 1.56 60013 6759 2 1104.616374 553.3162 ATPase family AAA domain-containing protein 3C OS=Homo sapiens OX=9606 GN=ATAD3C PE=2 SV=2 8.5 1724.5 - 521647 - - - -1.3905 - 1.578 0.394 - 211.4 1 1 0 -0.0015 10 0 0 0 1.09E+07 6.96E+06 - - - 3.2239 0.8323 221125_WJC_METTL3_EV_vs_WT_F05.06760.06760.2 0.000748 18-Aug E.YVLK[136.11]PATEGK[136.11].R "sp|Q5T2N8|ATD3C_HUMAN,sp|Q9NVI7|ATD3A_HUMAN,tr|Q5SV16|Q5SV16_HUMAN" 3 1120.6463 1.56 60014 6760 2 1120.650987 561.3304 ATPase family AAA domain-containing protein 3C OS=Homo sapiens OX=9606 GN=ATAD3C PE=2 SV=2 8.5 1724.6 - 336782 - - - 4.1735 - 1.543 0.446 - 215.4 1 1 0 0.0047 10 0 0 0 1.08E+07 6.96E+06 - - - 3.5444 0.9972 221125_WJC_METTL3_EV_vs_WT_F05.06765.06765.2 1.75 16-Aug K.VQAELDETK.L "sp|O15498|YKT6_HUMAN,tr|A0A7I2V4L6|A0A7I2V4L6_HUMAN,tr|A0A7I2V3V7|A0A7I2V3V7_HUMAN,tr|H7C3K7|H7C3K7_HUMAN,tr|A0A7I2V3A1|A0A7I2V3A1_HUMAN" 5 1031.5135 5.97 60017 6765 2 1031.513253 516.764 Synaptobrevin homolog YKT6 OS=Homo sapiens OX=9606 GN=YKT6 PE=1 SV=1 4.14 1725.3 - 809158 - - - -0.2443 - 1.561 0.161 - 219.6 1 2 0 -0.0003 9 0 0 0 2.52E+07 4.22E+06 - - - 1.5184 0.9122 221125_WJC_METTL3_EV_vs_WT_F05.06768.06768.2 0.141 24-Mar K.REEGSDIEDEDME.E "sp|Q8NHQ9|DDX55_HUMAN,tr|F5H5U2|F5H5U2_HUMAN" 2 1552.5835 1.79 60020 6768 2 1552.582943 777.299 ATP-dependent RNA helicase DDX55 OS=Homo sapiens OX=9606 GN=DDX55 PE=1 SV=3 3.77 1725.6 - 607394 - - - -0.3658 - 0.99 0.401 - 14.7 1 1 0 -0.0006 13 0 0 0 2.42E+07 1.35E+07 - - - 1.9768 0.9257 221125_WJC_METTL3_EV_vs_WT_F05.06769.06769.2 7.87 12-May K.R[166.11]VTIMPK[136.11].D "sp|Q5TEC6|H3PS2_HUMAN,sp|Q16695|H31T_HUMAN,sp|P84243|H33_HUMAN,sp|Q6NXT2|H3C_HUMAN,sp|Q71DI3|H32_HUMAN,sp|P68431|H31_HUMAN,tr|K7EK07|K7EK07_HUMAN,tr|A0A590UJL8|A0A590UJL8_HUMAN" 8 861.5225 0.9 60021 6769 2 861.521568 431.7685 Histone HIST2H3PS2 OS=Homo sapiens OX=9606 GN=H3-2 PE=1 SV=1 11 1725.8 - 544221 - - - -1.0981 - 1.053 0.032 - 145.3 1 2 0 -0.0009 7 0 0 0 7.90E+07 8.79E+07 - - - -0.5593 0.9942 221125_WJC_METTL3_EV_vs_WT_F05.06774.06774.2 9.06E-05 22-Sep K.VGGTSDVEVNEK[136.11].K "sp|P10809|CH60_HUMAN,tr|A0A7I2V2X6|A0A7I2V2X6_HUMAN,tr|A0A7I2YQK6|A0A7I2YQK6_HUMAN,tr|A0A7I2V599|A0A7I2V599_HUMAN" 4 1240.6027 1.36 60024 6774 2 1240.595749 621.3086 "60 kDa heat shock protein, mitochondrial OS=Homo sapiens OX=9606 GN=HSPD1 PE=1 SV=2" 4.14 1726.4 - 233501 - - - -5.5715 - 1.973 0.438 - 272.3 1 2 0 -0.0069 12 0 0 0 6.30E+06 4.64E+06 - - - 4.0619 0.9983 221125_WJC_METTL3_EV_vs_WT_F05.06778.06778.2 0.00757 20-Jun R.EYNEDEDPAAR.R "sp|Q13123|RED_HUMAN,tr|D6RAY9|D6RAY9_HUMAN,tr|D6REL4|D6REL4_HUMAN,tr|E7EQZ7|E7EQZ7_HUMAN,tr|D6RCQ4|D6RCQ4_HUMAN" 5 1307.5266 1.32 60028 6778 2 1307.524431 654.7706 Protein Red OS=Homo sapiens OX=9606 GN=IK PE=1 SV=3 3.83 1727 - 159563 - - - -1.6504 - 1.064 0.428 - 106.3 1 2 0 -0.0022 11 0 0 0 1.19E+07 9.02E+06 - - - 2.3694 0.9993 221125_WJC_METTL3_EV_vs_WT_F05.06782.06782.2 0.741 16-Nov K.RVLLGETGK.E "sp|P62280|RS11_HUMAN,tr|M0QZC5|M0QZC5_HUMAN,tr|M0R1H6|M0R1H6_HUMAN" 3 971.5764 0.96 60030 6782 2 971.57575 486.7955 40S ribosomal protein S11 OS=Homo sapiens OX=9606 GN=RPS11 PE=1 SV=3 8.75 1727.4 - 1.89E+06 - - - -0.6484 - 1.997 0.241 - 465.4 1 2 0 -0.0006 9 0 0 0 4.60E+07 4.79E+07 - - - 2.8218 0.9251 221125_WJC_METTL3_EV_vs_WT_F05.06784.06784.3 0.178 Nov-32 K.TLLESER[166.11]ER[166.11].L "sp|O75792|RNH2A_HUMAN,tr|A0A2R8Y658|A0A2R8Y658_HUMAN" 2 1151.6049 0.001 60032 6784 3 1151.603413 384.8756 Ribonuclease H2 subunit A OS=Homo sapiens OX=9606 GN=RNASEH2A PE=1 SV=2 4.78 1727.6 - 938113 - - - -1.3268 - 1.525 0.158 - 202.2 1 2 1 -0.0015 9 0 0 0 0.00E+00 3.50E+07 - - - 1.5729 0.9998 221125_WJC_METTL3_EV_vs_WT_F05.06788.06788.2 0.000618 16-Sep R.AQFAEATQR.L sp|O94874|UFL1_HUMAN 1 1020.4989 1.99 60034 6788 2 1020.498304 511.2567 E3 UFM1-protein ligase 1 OS=Homo sapiens OX=9606 GN=UFL1 PE=1 SV=2 6.05 1728.1 - 2.29E+06 - - - -0.5429 - 2.045 0.398 - 435.9 1 2 0 -0.0006 9 0 0 0 5.27E+07 2.65E+07 - - - 4.0501 0.9979 221125_WJC_METTL3_EV_vs_WT_F05.06794.06794.2 6.24E-05 22-Sep K.VGGTSDVEVNEK.K "sp|P10809|CH60_HUMAN,tr|A0A7I2V2X6|A0A7I2V2X6_HUMAN,tr|A0A7I2YQK6|A0A7I2YQK6_HUMAN,tr|A0A7I2V599|A0A7I2V599_HUMAN" 4 1232.5885 1.18 60040 6794 2 1232.583725 617.3015 "60 kDa heat shock protein, mitochondrial OS=Homo sapiens OX=9606 GN=HSPD1 PE=1 SV=2" 4.14 1728.8 - 209049 - - - -3.8423 - 1.82 0.432 - 170.7 1 2 0 -0.0047 12 0 0 0 4.28E+06 3.62E+06 - - - 3.8059 0.9997 221125_WJC_METTL3_EV_vs_WT_F05.06798.06798.2 0.00413 14-Aug K.YC[160.03]VEEEEK.A "sp|P78347|GTF2I_HUMAN,tr|C9J6M0|C9J6M0_HUMAN,tr|A0A494C1K3|A0A494C1K3_HUMAN" 3 1084.4383 1.34 60042 6798 2 1084.436383 543.2264 General transcription factor II-I OS=Homo sapiens OX=9606 GN=GTF2I PE=1 SV=2 4.09 1729.3 - 1.62E+06 - - - -1.7594 - 1.634 0.528 - 154.7 1 2 0 -0.0019 8 0 0 0 3.15E+08 2.34E+08 - - - 4.4211 0.9992 221125_WJC_METTL3_EV_vs_WT_F05.06799.06799.2 0.00707 14-Aug R.QAFPNTNR.W sp|P26641|EF1G_HUMAN 1 946.4621 0.94 60043 6799 2 946.461441 474.2383 Elongation factor 1-gamma OS=Homo sapiens OX=9606 GN=EEF1G PE=1 SV=3 9.75 1729.4 - 1.29E+06 - - - -0.673 - 1.434 0.339 - 272 1 2 0 -0.0006 8 0 0 0 6.73E+07 7.18E+07 - - - 2.6318 0.9994 221125_WJC_METTL3_EV_vs_WT_F05.06800.06800.2 0.00382 12-Jun K.DNSEEFR.Q "sp|Q8WWM7|ATX2L_HUMAN,tr|H3BSK9|H3BSK9_HUMAN,tr|H3BUF6|H3BUF6_HUMAN" 3 895.3672 1.45 60044 6800 2 895.366076 448.6909 Ataxin-2-like protein OS=Homo sapiens OX=9606 GN=ATXN2L PE=1 SV=2 4.14 1729.5 - 1.65E+06 - - - -1.2274 - 1.481 0.396 - 317.3 1 2 0 -0.0011 7 0 0 0 1.29E+08 8.90E+07 - - - 3.2099 0.9991 221125_WJC_METTL3_EV_vs_WT_F05.06801.06801.2 0.00812 24-Dec K.GPGEVAGTVTGQK[136.11].R "sp|Q86U44|MTA70_HUMAN,tr|F5H6D8|F5H6D8_HUMAN,tr|H0YFV6|H0YFV6_HUMAN,tr|B4DTN4|B4DTN4_HUMAN" 4 1207.6288 0.01 60045 6801 2 1207.633522 604.8217 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 6 1729.6 - 381961 - - - 3.8969 - 2.542 0.501 - 649.2 1 2 0 0.0047 13 0 0 0 1.01E+05 1.86E+07 - - - 5.1344 0.9899 221125_WJC_METTL3_EV_vs_WT_F05.06802.06802.2 0.0618 18-Nov R.GAEQLAEGGR[166.11].M sp|Q08J23|NSUN2_HUMAN 1 996.4864 1.25 60046 6802 2 996.48135 499.2505 RNA cytosine C(5)-methyltransferase NSUN2 OS=Homo sapiens OX=9606 GN=NSUN2 PE=1 SV=2 4.53 1729.7 - 422640 - - - -5.0598 - 2.101 0.256 - 512.5 1 2 0 -0.005 10 0 0 0 3.07E+07 2.46E+07 - - - 3.0025 0.9997 221125_WJC_METTL3_EV_vs_WT_F05.06804.06804.2 0.000767 28-Dec R.MEAGEAAPPAGAGGR[166.11].A "sp|Q8N5Z5|KCD17_HUMAN,tr|A0A087WX35|A0A087WX35_HUMAN" 2 1350.6226 4.75 60048 6804 2 1350.619369 676.3186 BTB\POZ domain-containing protein KCTD17 OS=Homo sapiens OX=9606 GN=KCTD17 PE=1 SV=3 4.53 1729.9 - 220499 - - - -2.3685 - 2.536 0.517 - 324 1 2 0 -0.0032 15 0 0 0 7.05E+07 1.48E+07 - - - 5.1465 0.9999 221125_WJC_METTL3_EV_vs_WT_F05.06807.06807.2 7.29E-06 14/28 R.MEAGEAAPPAGAGGR.A "sp|Q8N5Z5|KCD17_HUMAN,tr|A0A087WX35|A0A087WX35_HUMAN" 2 1340.6143 4.02 60049 6807 2 1340.614179 671.3144 BTB\POZ domain-containing protein KCTD17 OS=Homo sapiens OX=9606 GN=KCTD17 PE=1 SV=3 4.53 1730.4 - 1.43E+06 - - - -0.0888 - 2.813 0.511 - 352.4 1 2 0 -0.0001 15 0 0 0 8.28E+07 2.06E+07 - - - 5.358 0.9985 221125_WJC_METTL3_EV_vs_WT_F05.06813.06813.2 0.0222 16-Aug R.EHGAFDAVK.C "sp|P11586|C1TC_HUMAN,tr|F5H2F4|F5H2F4_HUMAN,tr|V9GZ78|V9GZ78_HUMAN,tr|V9GYY3|V9GYY3_HUMAN,tr|A0A494C1T2|A0A494C1T2_HUMAN" 5 972.4665 1.37 60053 6813 2 972.467102 487.2405 "C-1-tetrahydrofolate synthase, cytoplasmic OS=Homo sapiens OX=9606 GN=MTHFD1 PE=1 SV=4" 5.32 1731.2 - 911769 - - - 0.6242 - 1.35 0.303 - 201.5 1 2 0 0.0006 9 0 0 0 4.61E+07 3.37E+07 - - - 2.147 0.9999 221125_WJC_METTL3_EV_vs_WT_F05.06815.06815.2 6.16E-06 20-Nov R.AEAAALSTQC[160.03]R.E sp|Q9H6T0|ESRP2_HUMAN 1 1176.5557 0.86 60055 6815 2 1176.556711 589.2851 Epithelial splicing regulatory protein 2 OS=Homo sapiens OX=9606 GN=ESRP2 PE=1 SV=1 6.04 1731.4 - 1.20E+06 - - - 0.8414 - 2.51 0.464 - 567.8 1 2 0 0.001 11 0 0 0 1.99E+07 2.32E+07 - - - 4.9574 0.8104 221125_WJC_METTL3_EV_vs_WT_F05.06819.06819.2 2.8 12-Jun K.HIFPASR.W "sp|Q14320|FA50A_HUMAN,sp|Q9Y247|FA50B_HUMAN" 2 826.445 0.53 60059 6819 2 826.447683 414.2298 Protein FAM50A OS=Homo sapiens OX=9606 GN=FAM50A PE=1 SV=2 9.76 1731.9 - 241867 - - - 3.2803 - 1.087 0.073 - 118.4 2 2 0 0.0027 7 0 0 0 6.35E+06 1.20E+07 - - - -0.2908 0.9995 221125_WJC_METTL3_EV_vs_WT_F05.06822.06822.2 7.90E-05 16-Oct R.EHGAFDAVK[136.11].C "sp|P11586|C1TC_HUMAN,tr|F5H2F4|F5H2F4_HUMAN,tr|V9GZ78|V9GZ78_HUMAN,tr|V9GYY3|V9GYY3_HUMAN,tr|A0A494C1T2|A0A494C1T2_HUMAN" 5 980.4807 1.8 60060 6822 2 980.480528 491.2476 "C-1-tetrahydrofolate synthase, cytoplasmic OS=Homo sapiens OX=9606 GN=MTHFD1 PE=1 SV=4" 5.32 1732.3 - 1.02E+06 - - - -0.1703 - 1.651 0.348 - 283.4 1 2 0 -0.0002 9 0 0 0 6.31E+07 3.51E+07 - - - 3.0618 0.9934 221125_WJC_METTL3_EV_vs_WT_F05.06824.06824.2 0.292 12-Jul K.RVTIMPK.D "sp|Q5TEC6|H3PS2_HUMAN,sp|Q16695|H31T_HUMAN,sp|P84243|H33_HUMAN,sp|Q6NXT2|H3C_HUMAN,sp|Q71DI3|H32_HUMAN,sp|P68431|H31_HUMAN,tr|K7EK07|K7EK07_HUMAN,tr|A0A590UJL8|A0A590UJL8_HUMAN" 8 843.5 0.9 60062 6824 2 843.500175 422.7573 Histone HIST2H3PS2 OS=Homo sapiens OX=9606 GN=H3-2 PE=1 SV=1 11 1732.5 - 2.93E+06 - - - 0.1553 - 1.399 0.109 - 265.7 1 2 0 0.0001 7 0 0 0 7.88E+07 8.79E+07 - - - 0.9099 0.9997 221125_WJC_METTL3_EV_vs_WT_F05.06825.06825.2 0.00414 20-Jul R.EYNEDEDPAAR[166.11].R "sp|Q13123|RED_HUMAN,tr|D6RAY9|D6RAY9_HUMAN,tr|D6REL4|D6REL4_HUMAN,tr|E7EQZ7|E7EQZ7_HUMAN,tr|D6RCQ4|D6RCQ4_HUMAN" 5 1317.5349 1.32 60063 6825 2 1317.535554 659.7747 Protein Red OS=Homo sapiens OX=9606 GN=IK PE=1 SV=3 3.83 1732.6 - 226798 - - - 0.5275 - 1.553 0.49 - 125.3 1 2 0 0.0007 11 0 0 0 1.19E+07 9.02E+06 - - - 3.8507 0.7702 221125_WJC_METTL3_EV_vs_WT_F05.06830.06830.2 0.959 16-Jun K.TLLESER[166.11]ER[166.11].L "sp|O75792|RNH2A_HUMAN,tr|A0A2R8Y658|A0A2R8Y658_HUMAN" 2 1151.6049 1.62 60066 6830 2 1151.60644 576.8097 Ribonuclease H2 subunit A OS=Homo sapiens OX=9606 GN=RNASEH2A PE=1 SV=2 4.78 1733.2 - 259848 - - - 1.3017 - 1.13 0.118 - 77.4 1 2 1 0.0015 9 0 0 0 8.77E+06 5.42E+06 - - - 0.2657 0.9877 221125_WJC_METTL3_EV_vs_WT_F05.06832.06832.2 0.185 14-Jun R.SEPIYNSR.C sp|Q5T749|KPRP_HUMAN 1 964.4614 13.32 60068 6832 2 964.461206 483.238 Keratinocyte proline-rich protein OS=Homo sapiens OX=9606 GN=KPRP PE=1 SV=1 5.72 1733.4 - 548453 - - - -0.2115 - 1.051 0.174 - 121.5 1 2 0 -0.0002 8 0 0 0 1.00E+08 7.52E+06 - - - 0.4761 0.9984 221125_WJC_METTL3_EV_vs_WT_F05.06844.06844.2 0.0348 20-Nov R.QVAPGAPSAPR.R "sp|Q8ND56|LS14A_HUMAN,tr|A0A140TA76|A0A140TA76_HUMAN,tr|K7EMZ9|K7EMZ9_HUMAN" 3 1049.5618 1.42 60075 6844 2 1049.563328 525.7882 Protein LSM14 homolog A OS=Homo sapiens OX=9606 GN=LSM14A PE=1 SV=3 9.75 1734.9 - 2.36E+06 - - - 1.4635 - 1.782 0.246 - 461.9 1 2 0 0.0015 11 0 0 0 4.09E+08 2.89E+08 - - - 2.4204 0.9981 221125_WJC_METTL3_EV_vs_WT_F05.06846.06846.2 0.0433 16-Sep R.AQEIAMQNR[166.11].L "sp|Q9HCC0|MCCB_HUMAN,tr|A0A804HJW5|A0A804HJW5_HUMAN,tr|A0A0G2JM88|A0A0G2JM88_HUMAN,tr|A0A804HK37|A0A804HK37_HUMAN,tr|A0A804HIH3|A0A804HIH3_HUMAN,tr|A0A804HJ24|A0A804HJ24_HUMAN,tr|A0A804HL02|A0A804HL02_HUMAN,tr|A0A804HKE8|A0A804HKE8_HUMAN,tr|D6RDF7|D6RDF7_HUMAN,tr|A0A804HJ84|A0A804HJ84_HUMAN,tr|A0A804HJW2|A0A804HJW2_HUMAN,tr|A0A804HLJ9|A0A804HLJ9_HUMAN,tr|D6R9R1|D6R9R1_HUMAN,tr|A0A804HHS4|A0A804HHS4_HUMAN,tr|A0A0S2Z5R4|A0A0S2Z5R4_HUMAN,tr|A0A804HJ31|A0A804HJ31_HUMAN" 16 1069.5214 0.48 60077 6846 2 1069.518428 535.768 "Methylcrotonoyl-CoA carboxylase beta chain, mitochondrial OS=Homo sapiens OX=9606 GN=MCCC2 PE=1 SV=1" 6.05 1735 - 1.01E+06 - - - -2.7769 - 1.807 0.307 - 293.6 1 2 0 -0.003 9 0 0 0 9.13E+06 1.90E+07 - - - 3.0193 0.9982 221125_WJC_METTL3_EV_vs_WT_F05.06847.06847.2 0.0159 16-Jul R.NPHTLGLSR[166.11].Y sp|Q9H7S9|ZN703_HUMAN 1 1003.5438 1.43 60078 6847 2 1003.544988 502.7792 Zinc finger protein 703 OS=Homo sapiens OX=9606 GN=ZNF703 PE=1 SV=1 9.76 1735.1 - 665771 - - - 1.136 - 1.486 0.267 - 158.2 1 2 0 0.0011 9 0 0 0 6.84E+07 4.78E+07 - - - 2.1586 0.9915 221125_WJC_METTL3_EV_vs_WT_F05.06848.06848.2 3.07 18-Sep K.AAQALSVQDK.G sp|P41440|S19A1_HUMAN 1 1029.5455 0.85 60079 6848 2 1029.54723 515.78 Reduced folate transporter OS=Homo sapiens OX=9606 GN=SLC19A1 PE=1 SV=3 5.88 1735.2 - 423519 - - - 1.7056 - 1.652 0.102 - 232.6 1 2 0 0.0018 10 0 0 0 1.12E+07 1.31E+07 - - - 1.195 0.9689 221125_WJC_METTL3_EV_vs_WT_F05.06850.06850.2 0.002 16-Jul R.SATNTTLPH.M "sp|Q8WXI9|P66B_HUMAN,tr|A0A0U1RRM1|A0A0U1RRM1_HUMAN,tr|A0A0U1RR30|A0A0U1RR30_HUMAN" 3 940.4614 - 60080 6850 2 940.462277 471.238 Transcriptional repressor p66-beta OS=Homo sapiens OX=9606 GN=GATAD2B PE=1 SV=1 6.46 1735.5 - 2.22E+06 - - - 0.9219 - 1.397 0.433 - 177.5 1 1 0 0.0009 9 0 0 0 - - - - - 3.2061 0.8517 221125_WJC_METTL3_EV_vs_WT_F05.06852.06852.2 0.0512 16-Aug K.ETPTQVYQK[136.11].D "sp|Q5SW79|CE170_HUMAN,tr|H0Y2V6|H0Y2V6_HUMAN" 2 1100.5593 1.82 60081 6852 2 1100.567782 551.2869 Centrosomal protein of 170 kDa OS=Homo sapiens OX=9606 GN=CEP170 PE=1 SV=1 6.1 1735.8 - 579292 - - - 7.6716 - 1.387 0.254 - 153.7 1 2 0 0.0084 9 0 0 0 2.03E+07 1.11E+07 - - - 1.8608 0.992 221125_WJC_METTL3_EV_vs_WT_F05.06854.06854.2 0.162 20-Apr R.QSMAQAEEETR[166.11].S sp|P55199|ELL_HUMAN 1 1288.5593 0.18 60083 6854 2 1288.559337 645.2869 RNA polymerase II elongation factor ELL OS=Homo sapiens OX=9606 GN=ELL PE=1 SV=1 4.25 1736 - 115998 - - - 0.0295 - 1.041 0.22 - 35.9 1 2 0 0 11 0 0 0 6.55E+05 3.72E+06 - - - 0.7746 0.997 221125_WJC_METTL3_EV_vs_WT_F05.06859.06859.3 0.0413 Nov-32 R.YYNKVPVEK.R "sp|P11387|TOP1_HUMAN,tr|A0A7P0T852|A0A7P0T852_HUMAN" 2 1138.6023 0.47 60086 6859 3 1138.603683 380.5414 DNA topoisomerase 1 OS=Homo sapiens OX=9606 GN=TOP1 PE=1 SV=2 8.43 1736.7 - 752935 - - - 1.2498 - 1.988 0.285 - 108.4 1 2 1 0.0014 9 0 0 0 1.18E+07 2.51E+07 - - - 3.7879 0.9983 221125_WJC_METTL3_EV_vs_WT_F05.06862.06862.2 0.0102 24-Sep R.APGPQAGPGPGVR.D "sp|O76024|WFS1_HUMAN,tr|A0A804HIL0|A0A804HIL0_HUMAN,tr|A0A669KAX3|A0A669KAX3_HUMAN,tr|A0A804HK77|A0A804HK77_HUMAN,tr|A0A804HKM5|A0A804HKM5_HUMAN,tr|A0A804HIL2|A0A804HIL2_HUMAN" 6 1159.6098 0.52 60089 6862 2 1159.611414 580.8122 Wolframin OS=Homo sapiens OX=9606 GN=WFS1 PE=1 SV=2 9.79 1737 - 140206 - - - 1.3875 - 1.688 0.265 - 210.6 1 2 0 0.0016 13 0 0 0 8.43E+06 1.62E+07 - - - 2.3415 0.9983 221125_WJC_METTL3_EV_vs_WT_F05.06868.06868.2 0.284 20-Dec R.QVAPGAPSAPR[166.11].R "sp|Q8ND56|LS14A_HUMAN,tr|A0A140TA76|A0A140TA76_HUMAN,tr|K7EMZ9|K7EMZ9_HUMAN" 3 1059.5701 1.42 60093 6868 2 1059.571901 530.7923 Protein LSM14 homolog A OS=Homo sapiens OX=9606 GN=LSM14A PE=1 SV=3 9.75 1737.7 - 4.35E+06 - - - 1.7356 - 1.936 0.226 - 546 1 2 0 0.0018 11 0 0 0 4.09E+08 2.89E+08 - - - 2.4968 0.9975 221125_WJC_METTL3_EV_vs_WT_F05.06869.06869.2 0.0675 14-Oct R.R[166.11]PTWAEER[166.11].R "sp|Q8ND56|LS14A_HUMAN,tr|A0A096LP11|A0A096LP11_HUMAN,tr|A0A140TA76|A0A140TA76_HUMAN,tr|A0A0G2JQ95|A0A0G2JQ95_HUMAN" 4 1063.5314 1.71 60094 6869 2 1063.532498 532.773 Protein LSM14 homolog A OS=Homo sapiens OX=9606 GN=LSM14A PE=1 SV=3 6.14 1737.7 - 3.23E+06 - - - 1.0493 - 2.044 0.091 - 340.8 1 2 0 0.0011 8 0 0 0 1.15E+08 6.74E+07 - - - 1.8689 0.9981 221125_WJC_METTL3_EV_vs_WT_F05.06871.06871.2 0.0259 20-Nov R.VQELAPASGEK.A "sp|Q14687|GSE1_HUMAN,tr|H7C3B5|H7C3B5_HUMAN,tr|H0Y613|H0Y613_HUMAN" 3 1127.5823 2.74 60096 6871 2 1127.585435 564.7984 Genetic suppressor element 1 OS=Homo sapiens OX=9606 GN=GSE1 PE=1 SV=3 4.53 1737.9 - 931590 - - - 2.822 - 2.209 0.258 - 475.7 1 2 0 0.0032 11 0 0 0 5.43E+07 1.98E+07 - - - 3.0896 0.9948 221125_WJC_METTL3_EV_vs_WT_F05.06873.06873.2 0.121 16-Jul R.VAVLENQNK[136.11].T "sp|P16220|CREB1_HUMAN,sp|P18846|ATF1_HUMAN,tr|G5E998|G5E998_HUMAN,tr|E9PAR2|E9PAR2_HUMAN" 4 1021.5648 0.12 60098 6873 2 1021.565849 511.7897 Cyclic AMP-responsive element-binding protein 1 OS=Homo sapiens OX=9606 GN=CREB1 PE=1 SV=3 5.97 1738.1 - 588039 - - - 1.067 - 1.39 0.176 - 130.9 1 2 0 0.0011 9 0 0 0 6.36E+06 5.13E+07 - - - 1.2933 0.9785 221125_WJC_METTL3_EV_vs_WT_F05.06875.06875.2 0.622 14-Jun R.SFTTTIHK.V sp|Q13257|MD2L1_HUMAN 1 933.492 1.23 60100 6875 2 933.493135 467.7533 Mitotic spindle assembly checkpoint protein MAD2A OS=Homo sapiens OX=9606 GN=MAD2L1 PE=1 SV=1 8.49 1738.4 - 245747 - - - 1.2351 - 1.189 0.109 - 106.3 1 2 0 0.0012 8 0 0 0 9.98E+06 8.12E+06 - - - 0.3678 0.9991 221125_WJC_METTL3_EV_vs_WT_F05.06876.06876.2 0.0027 18-Sep R.ALQGDYDQSR.T sp|Q9Y6D9|MD1L1_HUMAN 1 1151.5207 2.06 60101 6876 2 1151.518238 576.7676 Mitotic spindle assembly checkpoint protein MAD1 OS=Homo sapiens OX=9606 GN=MAD1L1 PE=1 SV=2 4.21 1738.5 - 176860 - - - -2.1519 - 1.738 0.374 - 365 1 2 0 -0.0025 10 0 0 0 5.98E+07 2.90E+07 - - - 3.3454 0.9998 221125_WJC_METTL3_EV_vs_WT_F05.06879.06879.2 2.43E-05 18-Oct R.ESSNVVVTER.V sp|Q02413|DSG1_HUMAN 1 1118.5568 55.42 60102 6879 2 1118.558028 560.2857 Desmoglein-1 OS=Homo sapiens OX=9606 GN=DSG1 PE=1 SV=2 4.53 1738.9 - 889720 - - - 1.1273 - 2.087 0.493 - 392 1 2 0 0.0013 10 0 0 0 2.33E+08 4.21E+06 - - - 4.7355 0.9998 221125_WJC_METTL3_EV_vs_WT_F05.06880.06880.2 0.00109 18-Nov R.ALQGDYDQSR[166.11].T sp|Q9Y6D9|MD1L1_HUMAN 1 1161.529 2.01 60103 6880 2 1161.528534 581.7718 Mitotic spindle assembly checkpoint protein MAD1 OS=Homo sapiens OX=9606 GN=MAD1L1 PE=1 SV=2 4.21 1739.1 - 382988 - - - -0.3891 - 1.959 0.433 - 542.4 1 2 0 -0.0005 10 0 0 0 5.82E+07 2.90E+07 - - - 4.116 0.9904 221125_WJC_METTL3_EV_vs_WT_F05.06881.06881.2 0.341 14-Aug K.SAISDHLK.S "sp|Q9UFW8|CGBP1_HUMAN,tr|C9JUJ0|C9JUJ0_HUMAN" 2 869.4607 1.11 60104 6881 2 869.462066 435.7376 CGG triplet repeat-binding protein 1 OS=Homo sapiens OX=9606 GN=CGGBP1 PE=1 SV=2 6.46 1739.2 - 516514 - - - 1.5929 - 1.516 0.103 - 163.6 1 2 0 0.0014 8 0 0 0 1.33E+07 1.20E+07 - - - 1.0562 0.9967 221125_WJC_METTL3_EV_vs_WT_F05.06882.06882.2 0.0418 20-Jul R.IASDEEIQGTK[136.11].D "sp|Q8WX93|PALLD_HUMAN,tr|A0A3B3ISX8|A0A3B3ISX8_HUMAN" 2 1197.5968 0.38 60105 6882 2 1197.598562 599.8057 Palladin OS=Homo sapiens OX=9606 GN=PALLD PE=1 SV=3 4.14 1739.3 - 329743 - - - 1.432 - 1.347 0.263 - 120.4 1 2 0 0.0017 11 0 0 0 2.23E+06 5.91E+06 - - - 1.7888 0.9362 221125_WJC_METTL3_EV_vs_WT_F05.06883.06883.2 3.81 16-Jun R.SEGPDVSVK[136.11].L "sp|Q96JN0|LCOR_HUMAN,tr|A0A6Q8PG83|A0A6Q8PG83_HUMAN,tr|A0A6Q8PGR8|A0A6Q8PGR8_HUMAN,tr|A0A6Q8PGL8|A0A6Q8PGL8_HUMAN,tr|A0A6Q8PFM9|A0A6Q8PFM9_HUMAN" 5 924.4644 0.87 60106 6883 2 924.466401 463.2395 Ligand-dependent corepressor OS=Homo sapiens OX=9606 GN=LCOR PE=1 SV=2 4.37 1739.4 - 222415 - - - 2.1905 - 1.051 0.111 - 104 1 2 0 0.002 9 0 0 0 1.87E+07 2.14E+07 - - - 0.0041 0.9999 221125_WJC_METTL3_EV_vs_WT_F05.06890.06890.3 0.0168 13/36 K.LGVIEDHSNR[166.11].T "sp|Q58FF3|ENPLL_HUMAN,sp|P14625|ENPL_HUMAN,tr|A0A7P0T917|A0A7P0T917_HUMAN,tr|A0A7P0T823|A0A7P0T823_HUMAN,tr|A0A7P0TAE1|A0A7P0TAE1_HUMAN,tr|H0YIV0|H0YIV0_HUMAN,tr|A0A7P0TAY2|A0A7P0TAY2_HUMAN,tr|A0A087WT78|A0A087WT78_HUMAN,tr|A0A7P0TAT8|A0A7P0TAT8_HUMAN" 9 1148.5814 0.81 60111 6890 3 1148.583806 383.8677 Putative endoplasmin-like protein OS=Homo sapiens OX=9606 GN=HSP90B2P PE=5 SV=1 5.32 1740.3 - 1.07E+06 - - - 2.1339 - 2.837 0.436 - 178.7 1 2 0 0.0024 10 0 0 0 6.47E+07 7.96E+07 - - - 6.4456 1 221125_WJC_METTL3_EV_vs_WT_F05.06891.06891.3 2.71E-06 14/36 K.LGVIEDHSNR.T "sp|Q58FF3|ENPLL_HUMAN,sp|P14625|ENPL_HUMAN,tr|A0A7P0T917|A0A7P0T917_HUMAN,tr|A0A7P0T823|A0A7P0T823_HUMAN,tr|A0A7P0TAE1|A0A7P0TAE1_HUMAN,tr|H0YIV0|H0YIV0_HUMAN,tr|A0A7P0TAY2|A0A7P0TAY2_HUMAN,tr|A0A087WT78|A0A087WT78_HUMAN,tr|A0A7P0TAT8|A0A7P0TAT8_HUMAN" 9 1138.5731 0.8 60112 6891 3 1138.573596 380.5316 Putative endoplasmin-like protein OS=Homo sapiens OX=9606 GN=HSP90B2P PE=5 SV=1 5.32 1740.4 - 595147 - - - 0.4488 - 2.784 0.438 - 244.4 1 2 0 0.0005 10 0 0 0 6.47E+07 8.10E+07 - - - 6.4133 0.9925 221125_WJC_METTL3_EV_vs_WT_F05.06896.06896.2 0.013 18-Oct R.TEEPMETEPK[136.11].G "sp|Q14839|CHD4_HUMAN,tr|A0A2R8Y4X2|A0A2R8Y4X2_HUMAN,tr|A0A2U3TZM0|A0A2U3TZM0_HUMAN,tr|A0A2R8Y5M9|A0A2R8Y5M9_HUMAN,tr|A0A2R8Y445|A0A2R8Y445_HUMAN,tr|A0A2R8YD40|A0A2R8YD40_HUMAN,tr|A0A2R8Y5J0|A0A2R8Y5J0_HUMAN,tr|A0A2R8Y425|A0A2R8Y425_HUMAN,tr|A0A2R8YFK9|A0A2R8YFK9_HUMAN,tr|A0A2R8Y8C1|A0A2R8Y8C1_HUMAN,tr|A0A0C4DGG9|A0A0C4DGG9_HUMAN,tr|A0A2R8YFD8|A0A2R8YFD8_HUMAN,tr|A0A2R8YDW2|A0A2R8YDW2_HUMAN,tr|A0A2R8Y6G9|A0A2R8Y6G9_HUMAN,tr|A0A2R8Y7I0|A0A2R8Y7I0_HUMAN,tr|F5GWX5|F5GWX5_HUMAN,tr|A0A2R8YER1|A0A2R8YER1_HUMAN,tr|A0A2R8Y7M9|A0A2R8Y7M9_HUMAN,tr|A0A2R8Y521|A0A2R8Y521_HUMAN,tr|A0A2R8YDJ9|A0A2R8YDJ9_HUMAN,tr|A0A2R8Y212|A0A2R8Y212_HUMAN,tr|A0A2R8YE38|A0A2R8YE38_HUMAN" 22 1197.5315 2.23 60115 6896 2 1197.536719 599.773 Chromodomain-helicase-DNA-binding protein 4 OS=Homo sapiens OX=9606 GN=CHD4 PE=1 SV=2 4.09 1741.1 - 226008 - - - 4.3832 - 1.564 0.347 - 270.3 1 2 0 0.0052 10 0 0 0 1.74E+07 7.79E+06 - - - 2.8507 0.9989 221125_WJC_METTL3_EV_vs_WT_F05.06901.06901.2 0.0137 16-Jul R.SEGPDVSVK.L "sp|Q96JN0|LCOR_HUMAN,tr|A0A6Q8PG83|A0A6Q8PG83_HUMAN,tr|A0A6Q8PGR8|A0A6Q8PGR8_HUMAN,tr|A0A6Q8PGL8|A0A6Q8PGL8_HUMAN,tr|A0A6Q8PFM9|A0A6Q8PFM9_HUMAN" 5 916.4502 0.91 60118 6901 2 916.449037 459.2324 Ligand-dependent corepressor OS=Homo sapiens OX=9606 GN=LCOR PE=1 SV=2 4.37 1741.8 - 679375 - - - -1.2428 - 1.28 0.373 - 116.4 1 2 0 -0.0011 9 0 0 0 1.78E+07 1.97E+07 - - - 2.5098 0.9905 221125_WJC_METTL3_EV_vs_WT_F05.06902.06902.2 0.287 12-Jun R.HFTDSLK.M "sp|Q03112|MECOM_HUMAN,tr|E7EUL6|E7EUL6_HUMAN,tr|A0A0C3SFZ7|A0A0C3SFZ7_HUMAN" 3 846.4236 1.09 60119 6902 2 846.424102 424.2191 Histone-lysine N-methyltransferase MECOM OS=Homo sapiens OX=9606 GN=MECOM PE=1 SV=3 6.74 1741.9 - 638788 - - - 0.6309 - 1.252 0.152 - 67.1 2 2 0 0.0005 7 0 0 0 4.05E+07 3.71E+07 - - - 0.7411 0.9665 221125_WJC_METTL3_EV_vs_WT_F05.06906.06906.2 3.72 14-May K.DVPNNQLR.H "sp|Q9BYJ9|YTHD1_HUMAN,sp|Q7Z739|YTHD3_HUMAN,tr|A0A087X0Q1|A0A087X0Q1_HUMAN,tr|A0A024R7W5|A0A024R7W5_HUMAN,tr|A0A087WY31|A0A087WY31_HUMAN" 5 954.4883 2.09 60122 6906 2 954.488616 478.2514 YTH domain-containing family protein 1 OS=Homo sapiens OX=9606 GN=YTHDF1 PE=1 SV=1 5.84 1742.4 - 1.31E+06 - - - 0.3384 - 1.167 0.083 - 93.8 4 2 0 0.0003 8 0 0 0 3.64E+07 1.74E+07 - - - -0.1492 0.9973 221125_WJC_METTL3_EV_vs_WT_F05.06914.06914.2 0.0354 12-Sep R.HFTDSLK[136.11].M "sp|Q03112|MECOM_HUMAN,tr|E7EUL6|E7EUL6_HUMAN,tr|A0A0C3SFZ7|A0A0C3SFZ7_HUMAN" 3 854.4378 1.15 60127 6914 2 854.438567 428.2262 Histone-lysine N-methyltransferase MECOM OS=Homo sapiens OX=9606 GN=MECOM PE=1 SV=3 6.74 1743.3 - 654370 - - - 0.9351 - 1.717 0.135 - 304.9 1 2 0 0.0008 7 0 0 0 4.31E+07 3.74E+07 - - - 1.7507 0.8779 221125_WJC_METTL3_EV_vs_WT_F05.06915.06915.2 0.0497 12-Jun G.NFHAVYR.D sp|P05109|S10A8_HUMAN 1 905.4508 6.26 60128 6915 2 905.452025 453.7327 Protein S100-A8 OS=Homo sapiens OX=9606 GN=S100A8 PE=1 SV=1 8.75 1743.4 - 734771 - - - 1.3695 - 1.28 0.302 - 155.6 1 1 0 0.0012 7 0 0 0 1.06E+08 1.69E+07 - - - 2.0534 0.9842 221125_WJC_METTL3_EV_vs_WT_F05.06917.06917.2 0.128 18-Sep K.VAQPTITDNK[136.11].D "sp|P21333|FLNA_HUMAN,tr|Q60FE5|Q60FE5_HUMAN,tr|H0Y5F3|H0Y5F3_HUMAN" 3 1093.5859 1.55 60130 6917 2 1093.591309 547.8002 Filamin-A OS=Homo sapiens OX=9606 GN=FLNA PE=1 SV=4 5.81 1743.6 - 542790 - - - 4.9571 - 1.636 0.287 - 192.8 1 2 0 0.0054 10 0 0 0 1.33E+07 8.57E+06 - - - 2.5331 0.9987 221125_WJC_METTL3_EV_vs_WT_F05.06918.06918.2 0.0194 18-Sep K.VAQPTITDNK.D "sp|P21333|FLNA_HUMAN,tr|Q60FE5|Q60FE5_HUMAN,tr|H0Y5F3|H0Y5F3_HUMAN" 3 1085.5717 1.5 60131 6918 2 1085.572922 543.7931 Filamin-A OS=Homo sapiens OX=9606 GN=FLNA PE=1 SV=4 5.81 1743.7 - 407308 - - - 1.1367 - 1.431 0.321 - 202.1 1 2 0 0.0012 10 0 0 0 1.29E+07 8.61E+06 - - - 2.4118 0.9985 221125_WJC_METTL3_EV_vs_WT_F05.06922.06922.2 0.0002 20-Oct K.GVEAVAIHGGK.D sp|Q9UJV9|DDX41_HUMAN 1 1036.5665 0.23 60133 6922 2 1036.569469 519.2905 Probable ATP-dependent RNA helicase DDX41 OS=Homo sapiens OX=9606 GN=DDX41 PE=1 SV=2 6.75 1744.2 - 715534 - - - 2.8228 - 1.782 0.37 - 247.3 1 2 0 0.0029 11 0 0 0 1.55E+07 6.65E+07 - - - 3.3358 0.9988 221125_WJC_METTL3_EV_vs_WT_F05.06923.06923.2 0.0322 18-Aug K.LQEVEC[160.03]EEQR.L "sp|Q13596|SNX1_HUMAN,tr|H0YK42|H0YK42_HUMAN" 2 1318.5823 1.44 60134 6923 2 1318.586876 660.2984 Sorting nexin-1 OS=Homo sapiens OX=9606 GN=SNX1 PE=1 SV=3 4.09 1744.4 - 100294 - - - 3.4476 - 1.849 0.457 - 329.5 1 2 0 0.0045 10 0 0 0 2.01E+06 1.40E+06 - - - 4.1306 0.9998 221125_WJC_METTL3_EV_vs_WT_F05.06925.06925.3 0.0034 13/40 K.LVTC[160.03]TGYHQVR[166.11].V "sp|Q6RFH5|WDR74_HUMAN,tr|E9PS41|E9PS41_HUMAN" 2 1342.6691 0.07 60136 6925 3 1342.669678 448.5637 WD repeat-containing protein 74 OS=Homo sapiens OX=9606 GN=WDR74 PE=1 SV=1 8.23 1744.6 - 498411 - - - 0.4119 - 2.174 0.33 - 299.3 1 2 0 0.0006 11 0 0 0 5.81E+05 8.65E+06 - - - 4.4251 0.9994 221125_WJC_METTL3_EV_vs_WT_F05.06929.06929.2 0.684 18-Nov K.AYGELPEHAK.L "sp|O14602|IF1AY_HUMAN,sp|P47813|IF1AX_HUMAN,tr|A6NJH9|A6NJH9_HUMAN,tr|X6RAC9|X6RAC9_HUMAN" 4 1113.5455 0.78 60138 6929 2 1113.546703 557.78 "Eukaryotic translation initiation factor 1A, Y-chromosomal OS=Homo sapiens OX=9606 GN=EIF1AY PE=1 SV=4" 5.4 1745.1 - 3.38E+06 - - - 1.1037 - 1.886 0.324 - 376.6 1 2 0 0.0012 10 0 0 0 1.43E+08 1.82E+08 - - - 3.2046 0.9999 221125_WJC_METTL3_EV_vs_WT_F05.06933.06933.2 0.000234 20-Oct K.EMDEAATAEER.G "sp|Q04637|IF4G1_HUMAN,tr|E7EUU4|E7EUU4_HUMAN,tr|E9PGM1|E9PGM1_HUMAN,tr|C9J6B6|C9J6B6_HUMAN,tr|E7EX73|E7EX73_HUMAN,tr|A0A7I2Y1C3|A0A7I2Y1C3_HUMAN,tr|C9JF13|C9JF13_HUMAN" 7 1250.5085 0.92 60142 6933 2 1250.508524 626.2615 Eukaryotic translation initiation factor 4 gamma 1 OS=Homo sapiens OX=9606 GN=EIF4G1 PE=1 SV=4 3.91 1745.5 - 214354 - - - 0.0224 - 2.221 0.497 - 525.5 1 2 0 0 11 0 0 0 4.62E+06 5.03E+06 - - - 4.8705 0.9998 221125_WJC_METTL3_EV_vs_WT_F05.06936.06936.2 5.09E-05 14-Sep K.GNFHAVYR.D sp|P05109|S10A8_HUMAN 1 962.4722 50.94 60143 6936 2 962.472578 482.2434 Protein S100-A8 OS=Homo sapiens OX=9606 GN=S100A8 PE=1 SV=1 8.75 1745.9 - 8.32E+06 - - - 0.3418 - 1.726 0.465 - 435.5 1 2 0 0.0003 8 0 0 0 2.82E+08 5.54E+06 - - - 4.1215 0.9994 221125_WJC_METTL3_EV_vs_WT_F05.06937.06937.2 4.30E-07 20-Dec K.MDETDASSAVK.V "sp|Q13148|TADBP_HUMAN,tr|A0A087WX29|A0A087WX29_HUMAN,tr|G3V162|G3V162_HUMAN,tr|A0A087WYY0|A0A087WYY0_HUMAN,tr|K7EN94|K7EN94_HUMAN,tr|A0A0A0N0M3|A0A0A0N0M3_HUMAN,tr|B1AKP7|B1AKP7_HUMAN,tr|K7EJM5|K7EJM5_HUMAN,tr|A0A087X260|A0A087X260_HUMAN" 9 1152.4969 1.22 60144 6937 2 1152.500062 577.2557 TAR DNA-binding protein 43 OS=Homo sapiens OX=9606 GN=TARDBP PE=1 SV=1 4.03 1746 - 3.94E+06 - - - 2.7705 - 2.273 0.424 - 570.9 1 2 0 0.0032 11 0 0 0 8.85E+07 7.24E+07 - - - 4.3929 0.9998 221125_WJC_METTL3_EV_vs_WT_F05.06938.06938.2 0.00243 20-Nov K.MDETDASSAVK[136.11].V "sp|Q13148|TADBP_HUMAN,tr|A0A087WX29|A0A087WX29_HUMAN,tr|G3V162|G3V162_HUMAN,tr|A0A087WYY0|A0A087WYY0_HUMAN,tr|K7EN94|K7EN94_HUMAN,tr|A0A0A0N0M3|A0A0A0N0M3_HUMAN,tr|B1AKP7|B1AKP7_HUMAN,tr|K7EJM5|K7EJM5_HUMAN,tr|A0A087X260|A0A087X260_HUMAN" 9 1160.5111 1.22 60145 6938 2 1160.511972 581.2628 TAR DNA-binding protein 43 OS=Homo sapiens OX=9606 GN=TARDBP PE=1 SV=1 4.03 1746 - 2.88E+06 - - - 0.7781 - 1.986 0.473 - 397.5 1 2 0 0.0009 11 0 0 0 8.84E+07 7.24E+07 - - - 4.3904 0.9814 221125_WJC_METTL3_EV_vs_WT_F05.06941.06941.2 0.00114 16-Sep L.GVIEDHSNR.T "sp|Q58FF3|ENPLL_HUMAN,sp|P14625|ENPL_HUMAN,tr|A0A7P0T917|A0A7P0T917_HUMAN,tr|A0A7P0T823|A0A7P0T823_HUMAN,tr|A0A7P0TAE1|A0A7P0TAE1_HUMAN,tr|H0YIV0|H0YIV0_HUMAN,tr|A0A7P0TAY2|A0A7P0TAY2_HUMAN,tr|A0A087WT78|A0A087WT78_HUMAN,tr|A0A7P0TAT8|A0A7P0TAT8_HUMAN" 9 1025.489 1.06 60148 6941 2 1025.48822 513.7518 Putative endoplasmin-like protein OS=Homo sapiens OX=9606 GN=HSP90B2P PE=5 SV=1 5.32 1746.3 - 477226 - - - -0.7811 - 1.682 0.418 - 311.8 1 1 0 -0.0008 9 0 0 0 1.40E+07 1.32E+07 - - - 3.6324 0.9998 221125_WJC_METTL3_EV_vs_WT_F05.06943.06943.2 0.0453 20-Sep K.EMDEAATAEER[166.11].G "sp|Q04637|IF4G1_HUMAN,tr|E7EUU4|E7EUU4_HUMAN,tr|E9PGM1|E9PGM1_HUMAN,tr|C9J6B6|C9J6B6_HUMAN,tr|E7EX73|E7EX73_HUMAN,tr|A0A7I2Y1C3|A0A7I2Y1C3_HUMAN,tr|C9JF13|C9JF13_HUMAN" 7 1260.5168 0.92 60150 6943 2 1260.515413 631.2657 Eukaryotic translation initiation factor 4 gamma 1 OS=Homo sapiens OX=9606 GN=EIF4G1 PE=1 SV=4 3.91 1746.6 - 221850 - - - -1.0734 - 1.929 0.453 - 392.7 1 2 0 -0.0014 11 0 0 0 4.62E+06 5.03E+06 - - - 4.1638 0.8752 221125_WJC_METTL3_EV_vs_WT_F05.06951.06951.3 6.1 Aug-40 R.ADPYRPVASPR.T sp|O60481|ZIC3_HUMAN 1 1227.636 2.77 60155 6951 3 1227.635917 410.2193 Zinc finger protein ZIC 3 OS=Homo sapiens OX=9606 GN=ZIC3 PE=1 SV=1 8.79 1747.4 - 690856 - - - -0.0839 - 1.26 0.1 - 85 1 2 0 -0.0001 11 0 0 0 1.60E+07 5.77E+06 - - - 0.3114 0.9791 221125_WJC_METTL3_EV_vs_WT_F05.06955.06955.2 0.598 14-Jun K.KGPNPLMR.R "sp|Q16875|F263_HUMAN,tr|A0A1W2PR17|A0A1W2PR17_HUMAN,tr|Q9H178|Q9H178_HUMAN,tr|Q5W015|Q5W015_HUMAN,tr|Q5VX20|Q5VX20_HUMAN" 5 911.5011 2.68 60157 6955 2 911.502205 456.7578 "6-phosphofructo-2-kinase\fructose-2,6-bisphosphatase 3 OS=Homo sapiens OX=9606 GN=PFKFB3 PE=1 SV=1" 11 1748 - 338998 - - - 1.2057 - 1.37 0.052 - 146.1 1 2 0 0.0011 8 0 0 0 1.25E+07 4.65E+06 - - - 0.3742 0.9998 221125_WJC_METTL3_EV_vs_WT_F05.06956.06956.2 3.52E-06 18-Sep K.LTQDQDVDVK[136.11].Y "sp|P30153|2AAA_HUMAN,tr|E9PH38|E9PH38_HUMAN,tr|B3KQV6|B3KQV6_HUMAN" 3 1167.5863 0.79 60158 6956 2 1167.584839 584.8004 Serine\threonine-protein phosphatase 2A 65 kDa regulatory subunit A alpha isoform OS=Homo sapiens OX=9606 GN=PPP2R1A PE=1 SV=4 3.93 1748.1 - 337924 - - - -1.2359 - 2.026 0.527 - 307.3 1 2 0 -0.0014 10 0 0 0 1.76E+08 2.24E+08 - - - 4.9038 0.9997 221125_WJC_METTL3_EV_vs_WT_F05.06958.06958.2 0.304 16-Nov R.KIILSDEGK.M "sp|Q15562|TEAD2_HUMAN,sp|P28347|TEAD1_HUMAN,sp|Q15561|TEAD4_HUMAN,sp|Q99594|TEAD3_HUMAN,tr|A0A1X7SBS4|A0A1X7SBS4_HUMAN,tr|Q53GI4|Q53GI4_HUMAN,tr|H0YE88|H0YE88_HUMAN,tr|H0YCZ6|H0YCZ6_HUMAN,tr|H0YGS2|H0YGS2_HUMAN,tr|H0Y7B0|H0Y7B0_HUMAN,tr|H0YEJ9|H0YEJ9_HUMAN,tr|B5MCM0|B5MCM0_HUMAN,tr|A0A0A0MRF3|A0A0A0MRF3_HUMAN,tr|A0A7P0SNI2|A0A7P0SNI2_HUMAN" 14 1001.5757 2.49 60160 6958 2 1001.575698 501.7951 Transcriptional enhancer factor TEF-4 OS=Homo sapiens OX=9606 GN=TEAD2 PE=1 SV=2 6.07 1748.3 - 356740 - - - -0.013 - 2.035 0.322 - 405.1 1 2 0 0 9 0 0 0 9.69E+06 3.88E+06 - - - 3.4748 0.9719 221125_WJC_METTL3_EV_vs_WT_F05.06961.06961.2 0.0323 14-Aug Y.GELPEHAK.L "sp|O14602|IF1AY_HUMAN,sp|P47813|IF1AX_HUMAN,tr|A6NJH9|A6NJH9_HUMAN,tr|X6RAC9|X6RAC9_HUMAN" 4 879.445 0.76 60162 6961 2 879.444783 440.7298 "Eukaryotic translation initiation factor 1A, Y-chromosomal OS=Homo sapiens OX=9606 GN=EIF1AY PE=1 SV=4" 5.4 1748.7 - 4.06E+06 - - - -0.282 - 1.495 0.38 - 236.3 1 1 0 -0.0002 8 0 0 0 9.41E+07 1.24E+08 - - - 3.0604 0.9958 221125_WJC_METTL3_EV_vs_WT_F05.06964.06964.3 0.0182 Oct-40 R.VFTTVGSAEK[136.11]R[166.11].A "sp|P49327|FAS_HUMAN,tr|A0A0U1RQF0|A0A0U1RQF0_HUMAN" 2 1211.6629 0.51 60164 6964 3 1211.661497 404.8949 Fatty acid synthase OS=Homo sapiens OX=9606 GN=FASN PE=1 SV=3 8.72 1749 - 260208 - - - -1.1637 - 1.702 0.21 - 127.5 1 2 0 -0.0014 11 0 0 0 5.41E+06 1.05E+07 - - - 2.3917 0.9871 221125_WJC_METTL3_EV_vs_WT_F05.06965.06965.2 0.0653 14-Jun K.ELYIQHAK[136.11].E sp|Q00059|TFAM_HUMAN 1 1008.5484 1.36 60165 6965 2 1008.551425 505.2815 "Transcription factor A, mitochondrial OS=Homo sapiens OX=9606 GN=TFAM PE=1 SV=1" 6.85 1749.1 - 264360 - - - 3.0182 - 1.288 0.234 - 125.8 1 2 0 0.003 8 0 0 0 1.68E+07 1.23E+07 - - - 1.5317 0.9986 221125_WJC_METTL3_EV_vs_WT_F05.06968.06968.2 0.0199 12-Aug R.SQSWEER.G "sp|Q6Y7W6|GGYF2_HUMAN,tr|I1E4Y6|I1E4Y6_HUMAN,tr|E7ESB6|E7ESB6_HUMAN" 3 920.3988 1.48 60166 6968 2 920.39673 461.2067 GRB10-interacting GYF protein 2 OS=Homo sapiens OX=9606 GN=GIGYF2 PE=1 SV=1 4.53 1749.5 - 831817 - - - -2.2588 - 1.577 0.333 - 385.4 1 2 0 -0.0021 7 0 0 0 1.41E+07 9.50E+06 - - - 2.9432 0.9973 221125_WJC_METTL3_EV_vs_WT_F05.06969.06969.2 0.0322 18-Jul K.GSAITGPVAK.E "sp|P62829|RL23_HUMAN,tr|J3KTJ3|J3KTJ3_HUMAN" 2 899.5076 1.06 60167 6969 2 899.50698 450.7611 60S ribosomal protein L23 OS=Homo sapiens OX=9606 GN=RPL23 PE=1 SV=1 8.75 1749.7 - 488266 - - - -0.7248 - 1.265 0.278 - 128.3 2 2 0 -0.0007 10 0 0 0 1.17E+08 1.10E+08 - - - 1.6158 0.9429 221125_WJC_METTL3_EV_vs_WT_F05.06970.06970.2 0.0266 16-Jul A.QDSTDLVAK.L "sp|P17987|TCPA_HUMAN,tr|F5H282|F5H282_HUMAN,tr|E7EQR6|E7EQR6_HUMAN" 3 975.4873 0.01 60168 6970 2 975.487312 488.7509 T-complex protein 1 subunit alpha OS=Homo sapiens OX=9606 GN=TCP1 PE=1 SV=1 4.21 1749.7 - 508110 - - - 0.0226 - 1.422 0.312 - 157.1 1 1 0 0 9 0 0 0 1.93E+07 2.07E+09 - - - 2.364 0.9993 221125_WJC_METTL3_EV_vs_WT_F05.06971.06971.2 0.0181 12-Aug R.SQSWEER[166.11].G "sp|Q6Y7W6|GGYF2_HUMAN,tr|I1E4Y6|I1E4Y6_HUMAN,tr|E7ESB6|E7ESB6_HUMAN" 3 930.4071 1.47 60169 6971 2 930.406239 466.2108 GRB10-interacting GYF protein 2 OS=Homo sapiens OX=9606 GN=GIGYF2 PE=1 SV=1 4.53 1749.9 - 459585 - - - -0.9028 - 1.536 0.32 - 376.4 1 2 0 -0.0008 7 0 0 0 1.41E+07 9.57E+06 - - - 2.7641 0.9914 221125_WJC_METTL3_EV_vs_WT_F05.06972.06972.2 0.415 14-Jul K.ELYIQHAK.E sp|Q00059|TFAM_HUMAN 1 1000.5342 1.35 60170 6972 2 1000.533 501.2744 "Transcription factor A, mitochondrial OS=Homo sapiens OX=9606 GN=TFAM PE=1 SV=1" 6.85 1750 - 383667 - - - -1.1804 - 1.266 0.156 - 164.5 1 2 0 -0.0012 8 0 0 0 1.66E+07 1.23E+07 - - - 0.9042 0.9872 221125_WJC_METTL3_EV_vs_WT_F05.06979.06979.2 0.113 16-Sep A.YGELPEHAK[136.11].L "sp|O14602|IF1AY_HUMAN,sp|P47813|IF1AX_HUMAN,tr|A6NJH9|A6NJH9_HUMAN,tr|X6RAC9|X6RAC9_HUMAN" 4 1050.5226 1.23 60175 6979 2 1050.522178 526.2686 "Eukaryotic translation initiation factor 1A, Y-chromosomal OS=Homo sapiens OX=9606 GN=EIF1AY PE=1 SV=4" 5.4 1750.9 - 1.86E+06 - - - -0.3636 - 1.682 0.466 - 258.5 1 1 0 -0.0004 9 0 0 0 8.27E+07 6.72E+07 - - - 3.9871 0.9905 221125_WJC_METTL3_EV_vs_WT_F05.06981.06981.3 0.132 Nov-32 R.LIEKEC[160.03]LEK.E "sp|Q8IX01|SUGP2_HUMAN,tr|M0R2Z9|M0R2Z9_HUMAN,tr|M0R3F6|M0R3F6_HUMAN" 3 1160.6111 0.57 60177 6981 3 1160.60961 387.8776 SURP and G-patch domain-containing protein 2 OS=Homo sapiens OX=9606 GN=SUGP2 PE=1 SV=2 4.79 1751.1 - 714774 - - - -1.2933 - 1.546 0.273 - 100.5 1 2 1 -0.0015 9 0 0 0 1.18E+07 2.08E+07 - - - 2.8963 0.8709 221125_WJC_METTL3_EV_vs_WT_F05.06982.06982.2 0.0109 14-Jul A.QYEDIAQK.S sp|P04264|K2C1_HUMAN 1 993.4767 149.06 60178 6982 2 993.476812 497.7456 "Keratin, type II cytoskeletal 1 OS=Homo sapiens OX=9606 GN=KRT1 PE=1 SV=6" 4.37 1751.2 - 548940 - - - 0.0876 - 1.255 0.258 - 218.5 1 1 0 0.0001 8 0 0 0 1.87E+07 1.25E+05 - - - 1.6316 0.9721 221125_WJC_METTL3_EV_vs_WT_F05.06983.06983.2 0.0641 12-Jul K.HGLTLER.R "sp|Q96F86|EDC3_HUMAN,tr|H3BSQ0|H3BSQ0_HUMAN,tr|H3BPN4|H3BPN4_HUMAN" 3 824.4505 1.55 60179 6983 2 824.45145 413.2325 Enhancer of mRNA-decapping protein 3 OS=Homo sapiens OX=9606 GN=EDC3 PE=1 SV=1 6.75 1751.3 - 516985 - - - 1.2117 - 1.248 0.06 - 119.9 1 2 0 0.001 7 0 0 0 3.54E+07 2.28E+07 - - - 0.1858 0.9978 221125_WJC_METTL3_EV_vs_WT_F05.06984.06984.3 0.485 Nov-40 R.LMAEDEEGYRK.L "sp|P51531|SMCA2_HUMAN,sp|P51532|SMCA4_HUMAN,tr|A0A2R8Y7S2|A0A2R8Y7S2_HUMAN,tr|A0A2R8Y7F3|A0A2R8Y7F3_HUMAN,tr|A0A2R8YGG3|A0A2R8YGG3_HUMAN,tr|A0A0U1RQZ9|A0A0U1RQZ9_HUMAN,tr|Q9HBD4|Q9HBD4_HUMAN,tr|A0A2R8Y440|A0A2R8Y440_HUMAN,tr|F6VDE0|F6VDE0_HUMAN,tr|A0A2R8YDA1|A0A2R8YDA1_HUMAN,tr|A0A2R8YG32|A0A2R8YG32_HUMAN,tr|A0A2R8YGP5|A0A2R8YGP5_HUMAN,tr|A0A2R8Y6N0|A0A2R8Y6N0_HUMAN,tr|A0A2R8Y4P4|A0A2R8Y4P4_HUMAN,tr|A0A2R8Y4C5|A0A2R8Y4C5_HUMAN" 15 1339.6078 0.93 60180 6984 3 1339.608017 447.5432 Probable global transcription activator SNF2L2 OS=Homo sapiens OX=9606 GN=SMARCA2 PE=1 SV=2 4.41 1751.4 - 383721 - - - 0.15 - 1.944 0.211 - 131.3 1 2 0 0.0002 11 0 0 0 6.78E+06 7.28E+06 - - - 2.7808 0.9999 221125_WJC_METTL3_EV_vs_WT_F05.06986.06986.2 9.81E-05 16-Sep K.ITITNDQNR[166.11].L "sp|P11021|BIP_HUMAN,tr|A0A7P0TB36|A0A7P0TB36_HUMAN,tr|A0A7P0TAI0|A0A7P0TAI0_HUMAN" 3 1083.5548 0.57 60181 6986 2 1083.554276 542.7847 Endoplasmic reticulum chaperone BiP OS=Homo sapiens OX=9606 GN=HSPA5 PE=1 SV=2 5.84 1751.6 - 1.21E+07 - - - -0.4891 - 1.984 0.505 - 289.4 1 2 0 -0.0005 9 0 0 0 1.84E+08 3.25E+08 - - - 4.7528 0.9998 221125_WJC_METTL3_EV_vs_WT_F05.06991.06991.2 0.000385 16-Aug K.EMAINDC[160.03]SK.A "sp|Q99614|TTC1_HUMAN,tr|A0A804HKC5|A0A804HKC5_HUMAN,tr|H0YB37|H0YB37_HUMAN,tr|A0A804HHT7|A0A804HHT7_HUMAN,tr|A0A804HIB8|A0A804HIB8_HUMAN,tr|A0A804HKI4|A0A804HKI4_HUMAN" 6 1066.4423 0.75 60185 6991 2 1066.44199 534.2284 Tetratricopeptide repeat protein 1 OS=Homo sapiens OX=9606 GN=TTC1 PE=1 SV=1 4.37 1752.2 - 411112 - - - -0.3198 - 1.55 0.483 - 195.1 1 2 0 -0.0003 9 0 0 0 8.69E+06 1.16E+07 - - - 3.8762 0.9995 221125_WJC_METTL3_EV_vs_WT_F05.06995.06995.2 0.00233 18-Oct K.GSAITGPVAK[136.11].E "sp|P62829|RL23_HUMAN,tr|J3KTJ3|J3KTJ3_HUMAN" 2 907.5218 1.06 60187 6995 2 907.520504 454.7682 60S ribosomal protein L23 OS=Homo sapiens OX=9606 GN=RPL23 PE=1 SV=1 8.75 1752.8 - 2.83E+06 - - - -1.4633 - 1.673 0.414 - 389.9 1 2 0 -0.0013 10 0 0 0 1.17E+08 1.10E+08 - - - 3.5348 0.9948 221125_WJC_METTL3_EV_vs_WT_F05.07000.07000.2 0.0193 12-Aug K.VREYELR.K "sp|P62913|RL11_HUMAN,tr|Q5VVC8|Q5VVC8_HUMAN" 2 963.5138 3.96 60190 7000 2 963.513814 482.7642 60S ribosomal protein L11 OS=Homo sapiens OX=9606 GN=RPL11 PE=1 SV=2 6.11 1753.3 - 5.14E+06 - - - 0.0353 - 1.525 0.369 - 251.1 1 2 1 0 7 0 0 0 1.26E+08 3.18E+07 - - - 3.1035 0.9998 221125_WJC_METTL3_EV_vs_WT_F05.07007.07007.2 0.000622 20-Oct K.LTNQNDELEEK.V "sp|P82094|TMF1_HUMAN,tr|A0A2R8Y7M0|A0A2R8Y7M0_HUMAN" 2 1331.6205 1.61 60195 7007 2 1331.618976 666.8175 TATA element modulatory factor OS=Homo sapiens OX=9606 GN=TMF1 PE=1 SV=2 4 1754.2 - 418305 - - - -1.1362 - 2.259 0.448 - 506.1 1 2 0 -0.0015 11 0 0 0 1.18E+08 7.32E+07 - - - 4.554 0.9991 221125_WJC_METTL3_EV_vs_WT_F05.07011.07011.2 0.026 14-Sep K.TDSDIISK.M sp|P08579|RU2B_HUMAN 1 877.4393 1.15 60197 7011 2 877.438609 439.7269 U2 small nuclear ribonucleoprotein B'' OS=Homo sapiens OX=9606 GN=SNRPB2 PE=1 SV=1 4.21 1754.8 - 2.93E+06 - - - -0.7613 - 1.768 0.24 - 370.6 1 2 0 -0.0007 8 0 0 0 1.35E+08 1.17E+08 - - - 2.5321 0.9995 221125_WJC_METTL3_EV_vs_WT_F05.07012.07012.2 1.80E-05 18-Sep K.ISC[160.03]AGPQTYK.E sp|Q96KR1|ZFR_HUMAN 1 1123.5332 0.61 60198 7012 2 1123.530186 562.7739 Zinc finger RNA-binding protein OS=Homo sapiens OX=9606 GN=ZFR PE=1 SV=2 8.2 1754.8 - 994400 - - - -2.6782 - 1.803 0.509 - 236.6 1 2 0 -0.003 10 0 0 0 3.94E+07 6.43E+07 - - - 4.4449 0.9994 221125_WJC_METTL3_EV_vs_WT_F05.07016.07016.2 0.0311 14-Aug R.K[136.11]IVASFSK[136.11].R "sp|O94952|FBX21_HUMAN,tr|Q4G104|Q4G104_HUMAN,tr|H0YIE9|H0YIE9_HUMAN" 3 894.551 0.001 60202 7016 2 894.551133 448.2828 F-box only protein 21 OS=Homo sapiens OX=9606 GN=FBXO21 PE=2 SV=2 10 1755.2 - 472422 - - - 0.2012 - 1.91 0.257 - 266.4 1 2 0 0.0002 8 0 0 0 0.00E+00 1.20E+07 - - - 2.8908 0.999 221125_WJC_METTL3_EV_vs_WT_F05.07017.07017.2 0.00439 16-Sep R.QASQELDVK.R "sp|P46100|ATRX_HUMAN,tr|A0A6Q8PHA4|A0A6Q8PHA4_HUMAN" 2 1016.5138 0.8 60203 7017 2 1016.514962 509.2642 Transcriptional regulator ATRX OS=Homo sapiens OX=9606 GN=ATRX PE=1 SV=5 4.37 1755.4 - 389794 - - - 1.1048 - 1.624 0.301 - 351.8 1 2 0 0.0011 9 0 0 0 1.13E+07 1.41E+07 - - - 2.6667 0.9999 221125_WJC_METTL3_EV_vs_WT_F05.07018.07018.2 0.182 22-Dec R.LEAATQQNQQLR[166.11].A "sp|Q08379|GOGA2_HUMAN,tr|A0A6Q8KRG2|A0A6Q8KRG2_HUMAN,tr|A0A1W2PQY5|A0A1W2PQY5_HUMAN" 3 1408.7298 1.18 60204 7018 2 1408.730739 705.3722 Golgin subfamily A member 2 OS=Homo sapiens OX=9606 GN=GOLGA2 PE=1 SV=3 6 1755.5 - 191914 - - - 0.6587 - 2.563 0.473 - 672.9 1 2 0 0.0009 12 0 0 0 6.87E+06 5.83E+06 - - - 5.0107 0.9999 221125_WJC_METTL3_EV_vs_WT_F05.07020.07020.2 7.28E-06 18-Oct K.LTQDQDVDVK.Y "sp|P30153|2AAA_HUMAN,tr|E9PH38|E9PH38_HUMAN,tr|B3KQV6|B3KQV6_HUMAN" 3 1159.5721 0.79 60205 7020 2 1159.571762 580.7933 Serine\threonine-protein phosphatase 2A 65 kDa regulatory subunit A alpha isoform OS=Homo sapiens OX=9606 GN=PPP2R1A PE=1 SV=4 3.93 1755.7 - 8.88E+06 - - - -0.276 - 2.266 0.569 - 391.8 1 2 0 -0.0003 10 0 0 0 1.76E+08 2.24E+08 - - - 5.5269 0.9999 221125_WJC_METTL3_EV_vs_WT_F05.07024.07024.2 9.64E-06 20-Dec K.LTNQNDELEEK[136.11].V "sp|P82094|TMF1_HUMAN,tr|A0A2R8Y7M0|A0A2R8Y7M0_HUMAN" 2 1339.6347 1.61 60207 7024 2 1339.633972 670.8246 TATA element modulatory factor OS=Homo sapiens OX=9606 GN=TMF1 PE=1 SV=2 4 1756.2 - 1.12E+06 - - - -0.5352 - 2.425 0.506 - 722.6 1 2 0 -0.0007 11 0 0 0 1.18E+08 7.32E+07 - - - 5.1745 0.8874 221125_WJC_METTL3_EV_vs_WT_F05.07026.07026.2 0.003 16-Oct Y.TLVITDKEK.A "sp|P63173|RL38_HUMAN,tr|J3KT73|J3KT73_HUMAN,tr|J3QL01|J3QL01_HUMAN" 3 1045.6019 1.05 60209 7026 2 1045.602351 523.8082 60S ribosomal protein L38 OS=Homo sapiens OX=9606 GN=RPL38 PE=1 SV=2 5.73 1756.3 - 2.15E+06 - - - 0.4065 - 2.004 0.433 - 363 1 1 1 0.0004 9 0 0 0 4.46E+07 4.24E+07 - - - 4.2501 0.9997 221125_WJC_METTL3_EV_vs_WT_F05.07027.07027.2 0.00167 22-Oct R.LEAATQQNQQLR.A "sp|Q08379|GOGA2_HUMAN,tr|A0A6Q8KRG2|A0A6Q8KRG2_HUMAN,tr|A0A1W2PQY5|A0A1W2PQY5_HUMAN" 3 1398.7215 1.26 60210 7027 2 1398.722538 700.368 Golgin subfamily A member 2 OS=Homo sapiens OX=9606 GN=GOLGA2 PE=1 SV=3 6 1756.4 - 301691 - - - 0.7128 - 2.313 0.355 - 432 1 2 0 0.001 12 0 0 0 6.87E+06 5.47E+06 - - - 3.8691 0.9992 221125_WJC_METTL3_EV_vs_WT_F05.07032.07032.2 0.00124 16-Aug R.LNLESSNSK.Y "sp|P30260|CDC27_HUMAN,tr|I3L225|I3L225_HUMAN,tr|G5EA36|G5EA36_HUMAN,tr|F6QPS0|F6QPS0_HUMAN" 4 990.4982 0.75 60213 7032 2 990.499682 496.2564 Cell division cycle protein 27 homolog OS=Homo sapiens OX=9606 GN=CDC27 PE=1 SV=2 6 1756.9 - 607282 - - - 1.5073 - 1.69 0.349 - 182.4 1 2 0 0.0015 9 0 0 0 1.38E+07 1.85E+07 - - - 3.1363 0.9997 221125_WJC_METTL3_EV_vs_WT_F05.07033.07033.2 0.00291 16-Sep K.FNYSGSGGR.S sp|Q12906|ILF3_HUMAN 1 943.4148 1.31 60214 7033 2 943.415538 472.7147 Interleukin enhancer-binding factor 3 OS=Homo sapiens OX=9606 GN=ILF3 PE=1 SV=3 8.75 1757 - 2.87E+06 - - - 0.7886 - 1.808 0.422 - 258.8 1 2 0 0.0007 9 0 0 0 1.73E+08 1.32E+08 - - - 3.871 0.9997 221125_WJC_METTL3_EV_vs_WT_F05.07039.07039.2 0.00124 16-Nov R.TAQEVETYR.R "sp|P17844|DDX5_HUMAN,tr|J3QR02|J3QR02_HUMAN,tr|A0A7I2V507|A0A7I2V507_HUMAN,tr|J3KTA4|J3KTA4_HUMAN,tr|J3KTQ4|J3KTQ4_HUMAN,tr|A0A7I2V2S0|A0A7I2V2S0_HUMAN,tr|J3QRQ7|J3QRQ7_HUMAN" 7 1095.5197 15.46 60218 7039 2 1095.521551 548.7671 Probable ATP-dependent RNA helicase DDX5 OS=Homo sapiens OX=9606 GN=DDX5 PE=1 SV=1 4.53 1757.8 - 1.19E+06 - - - 1.7325 - 2.017 0.455 - 613.2 1 2 0 0.0019 9 0 0 0 3.63E+09 2.34E+08 - - - 4.4308 0.999 221125_WJC_METTL3_EV_vs_WT_F05.07046.07046.2 0.042 14-Sep K.TDSDIISK[136.11].M sp|P08579|RU2B_HUMAN 1 885.4535 1.17 60223 7046 2 885.453954 443.734 U2 small nuclear ribonucleoprotein B'' OS=Homo sapiens OX=9606 GN=SNRPB2 PE=1 SV=1 4.21 1758.6 - 4.41E+06 - - - 0.5387 - 1.956 0.191 - 383.5 1 2 0 0.0005 8 0 0 0 1.29E+08 1.10E+08 - - - 2.475 0.9915 221125_WJC_METTL3_EV_vs_WT_F05.07051.07051.2 0.747 16-Jun R.SEPSAGIPK[136.11].V "sp|Q9Y520|PRC2C_HUMAN,tr|E7EPN9|E7EPN9_HUMAN" 2 892.4745 1.37 60226 7051 2 892.475896 447.2445 Protein PRRC2C OS=Homo sapiens OX=9606 GN=PRRC2C PE=1 SV=4 5.72 1759.2 - 623400 - - - 1.5115 - 1.348 0.182 - 129.4 2 2 0 0.0013 9 0 0 0 5.04E+07 3.67E+07 - - - 1.1143 0.9779 221125_WJC_METTL3_EV_vs_WT_F05.07057.07057.2 0.0735 16-May K.EGIPPDQQR.L "sp|P62979|RS27A_HUMAN,sp|P0CG48|UBC_HUMAN,sp|P0CG48|UBC_HUMAN,sp|P0CG48|UBC_HUMAN,sp|P0CG48|UBC_HUMAN,sp|P0CG48|UBC_HUMAN,sp|P0CG48|UBC_HUMAN,sp|P0CG48|UBC_HUMAN,sp|P0CG48|UBC_HUMAN,sp|P0CG48|UBC_HUMAN,sp|P0CG47|UBB_HUMAN,sp|P0CG47|UBB_HUMAN,sp|P0CG47|UBB_HUMAN,sp|P62987|RL40_HUMAN,tr|F5H388|F5H388_HUMAN,tr|F5H388|F5H388_HUMAN,tr|F5GYU3|F5GYU3_HUMAN,tr|F5GYU3|F5GYU3_HUMAN,tr|B4DV12|B4DV12_HUMAN,tr|B4DV12|B4DV12_HUMAN,tr|J3QSA3|J3QSA3_HUMAN,tr|Q5PY61|Q5PY61_HUMAN,tr|Q5PY61|Q5PY61_HUMAN,tr|Q5PY61|Q5PY61_HUMAN,tr|F5H2Z3|F5H2Z3_HUMAN,tr|F5H2Z3|F5H2Z3_HUMAN,tr|M0R2S1|M0R2S1_HUMAN,tr|J3QS39|J3QS39_HUMAN,tr|J3QTR3|J3QTR3_HUMAN,tr|Q96C32|Q96C32_HUMAN,tr|Q96C32|Q96C32_HUMAN,tr|Q96C32|Q96C32_HUMAN,tr|Q96C32|Q96C32_HUMAN,tr|M0R1V7|M0R1V7_HUMAN,tr|F5H747|F5H747_HUMAN,tr|F5H747|F5H747_HUMAN,tr|F5GXK7|F5GXK7_HUMAN,tr|F5GXK7|F5GXK7_HUMAN,tr|M0R1M6|M0R1M6_HUMAN,tr|F5H6Q2|F5H6Q2_HUMAN,tr|F5H6Q2|F5H6Q2_HUMAN,tr|F5GZ39|F5GZ39_HUMAN,tr|J3QKN0|J3QKN0_HUMAN,tr|J3QKN0|J3QKN0_HUMAN,tr|J3QKN0|J3QKN0_HUMAN,tr|F5H265|F5H265_HUMAN,tr|F5H265|F5H265_HUMAN,tr|A0A2R8Y422|A0A2R8Y422_HUMAN" 48 1038.5094 0.47 60230 7057 2 1038.511887 520.262 Ubiquitin-40S ribosomal protein S27a OS=Homo sapiens OX=9606 GN=RPS27A PE=1 SV=2 4.37 1760 - 670476 - - - 2.3726 - 1.18 0.175 - 83.8 1 2 0 0.0025 9 0 0 0 2.28E+07 4.86E+07 - - - 0.8116 0.9972 221125_WJC_METTL3_EV_vs_WT_F05.07058.07058.2 0.00216 20-Aug R.YLQDNPASGEK[136.11].F sp|Q16850|CP51A_HUMAN 1 1228.5815 1.09 60231 7058 2 1228.576837 615.298 Lanosterol 14-alpha demethylase OS=Homo sapiens OX=9606 GN=CYP51A1 PE=1 SV=4 4.37 1760.1 - 97265 - - - -3.8207 - 1.38 0.474 - 127.6 1 2 0 -0.0047 11 0 0 0 1.60E+07 1.47E+07 - - - 3.4118 0.998 221125_WJC_METTL3_EV_vs_WT_F05.07060.07060.2 0.127 18-Jun R.NLENTQNQIK[136.11].A "sp|Q9BZF9|UACA_HUMAN,tr|H0YNH8|H0YNH8_HUMAN,tr|F5H2B9|F5H2B9_HUMAN" 3 1208.6241 1.77 60232 7060 2 1208.625271 605.3193 Uveal autoantigen with coiled-coil domains and ankyrin repeats OS=Homo sapiens OX=9606 GN=UACA PE=1 SV=2 6 1760.4 - 185769 - - - 0.9978 - 1.512 0.244 - 91.4 1 2 0 0.0012 10 0 0 0 5.18E+06 2.92E+06 - - - 1.9968 0.9994 221125_WJC_METTL3_EV_vs_WT_F05.07064.07064.2 0.00658 14-Aug K.DGTGWANK[136.11].Q sp|Q5JSZ5|PRC2B_HUMAN 1 855.3966 1.41 60235 7064 2 855.396953 428.7056 Protein PRRC2B OS=Homo sapiens OX=9606 GN=PRRC2B PE=1 SV=2 5.84 1760.9 - 1.66E+06 - - - 0.3764 - 1.598 0.321 - 284.7 1 2 0 0.0003 8 0 0 0 4.00E+07 2.83E+07 - - - 2.8255 0.7674 221125_WJC_METTL3_EV_vs_WT_F05.07066.07066.2 0.489 12-Jun N.KIDSEGR.S "sp|O75762|TRPA1_HUMAN,tr|H0YAW0|H0YAW0_HUMAN" 2 803.4137 5.41 60237 7066 2 803.414087 402.7141 Transient receptor potential cation channel subfamily A member 1 OS=Homo sapiens OX=9606 GN=TRPA1 PE=1 SV=3 6.07 1761.1 - 731580 - - - 0.4431 - 1.337 0.161 - 169.1 1 1 0 0.0004 7 0 0 0 2.69E+07 4.98E+06 - - - 1.1503 0.9958 221125_WJC_METTL3_EV_vs_WT_F05.07074.07074.2 0.369 14-Jul K.DGTGWANK.Q sp|Q5JSZ5|PRC2B_HUMAN 1 847.3824 0.45 60243 7074 2 847.382283 424.6985 Protein PRRC2B OS=Homo sapiens OX=9606 GN=PRRC2B PE=1 SV=2 5.84 1762.2 - 2.61E+06 - - - -0.1747 - 1.171 0.231 - 261.4 1 2 0 -0.0001 8 0 0 0 4.83E+07 1.08E+08 - - - 1.2232 0.9998 221125_WJC_METTL3_EV_vs_WT_F05.07075.07075.2 0.000188 16-Oct R.VNLVSGHVK[136.11].T "sp|P61962|DCAF7_HUMAN,tr|A0A087WWI6|A0A087WWI6_HUMAN" 2 959.5644 1.27 60244 7075 2 959.565017 480.7895 DDB1- and CUL4-associated factor 7 OS=Homo sapiens OX=9606 GN=DCAF7 PE=1 SV=1 8.73 1762.2 - 1.78E+06 - - - 0.6795 - 1.979 0.458 - 380.8 1 2 0 0.0007 9 0 0 0 6.40E+07 5.04E+07 - - - 4.3984 0.9149 221125_WJC_METTL3_EV_vs_WT_F05.07078.07078.2 2.95 16-Jun K.VQFGNENTK.L "sp|Q5T8P6|RBM26_HUMAN,tr|A0A087X0H9|A0A087X0H9_HUMAN" 2 1035.4985 0.94 60247 7078 2 1035.49757 518.7565 RNA-binding protein 26 OS=Homo sapiens OX=9606 GN=RBM26 PE=1 SV=3 5.97 1762.5 - 862150 - - - -0.9203 - 1.035 0.022 - 110 1 2 0 -0.001 9 0 0 0 2.86E+07 3.06E+07 - - - -0.6973 0.9986 221125_WJC_METTL3_EV_vs_WT_F05.07080.07080.2 0.00558 16-Jul K.VQFGNENTK[136.11].L "sp|Q5T8P6|RBM26_HUMAN,tr|A0A087X0H9|A0A087X0H9_HUMAN" 2 1043.5127 1.16 60249 7080 2 1043.511517 522.7636 RNA-binding protein 26 OS=Homo sapiens OX=9606 GN=RBM26 PE=1 SV=3 5.97 1762.7 - 731973 - - - -1.1557 - 1.573 0.262 - 228.5 1 2 0 -0.0012 9 0 0 0 3.67E+07 3.16E+07 - - - 2.2863 0.9989 221125_WJC_METTL3_EV_vs_WT_F05.07083.07083.2 0.00591 22-Aug K.MIGQATAADQEK.N sp|Q13015|AF1Q_HUMAN 1 1261.5973 1.27 60252 7083 2 1261.598637 631.8059 Protein AF1q OS=Homo sapiens OX=9606 GN=MLLT11 PE=1 SV=1 4.37 1763.1 - 237786 - - - 1.0986 - 1.617 0.313 - 113.2 1 2 0 0.0014 12 0 0 0 1.30E+07 1.02E+07 - - - 2.6169 0.953 221125_WJC_METTL3_EV_vs_WT_F05.07087.07087.2 1.8 14-Jul K.NLVGSEVK[136.11].L "sp|Q9Y4C1|KDM3A_HUMAN,tr|F8WE62|F8WE62_HUMAN" 2 852.4796 0.14 60254 7087 2 852.481347 427.2471 Lysine-specific demethylase 3A OS=Homo sapiens OX=9606 GN=KDM3A PE=1 SV=4 6 1763.6 - 1.65E+06 - - - 2.0118 - 1.356 0.024 - 163.1 1 2 0 0.0017 8 0 0 0 4.72E+06 3.39E+07 - - - 0.1362 0.9872 221125_WJC_METTL3_EV_vs_WT_F05.07088.07088.2 0.000156 24-Sep G.GGGGGLGSGGSIR.S sp|P35527|K1C9_HUMAN 1 1030.5156 2.94 60255 7088 2 1030.515575 516.2651 "Keratin, type I cytoskeletal 9 OS=Homo sapiens OX=9606 GN=KRT9 PE=1 SV=3" 9.75 1763.7 - 735432 - - - 0.0039 - 1.905 0.445 - 230.8 1 1 0 0 13 0 0 0 1.30E+07 4.42E+06 - - - 3.9819 0.9957 221125_WJC_METTL3_EV_vs_WT_F05.07090.07090.2 0.22 16-Sep R.EIESSPQYR[166.11].L "sp|Q8WWM7|ATX2L_HUMAN,tr|H3BSK9|H3BSK9_HUMAN,tr|H3BUF6|H3BUF6_HUMAN" 3 1117.5279 1.84 60257 7090 2 1117.530324 559.7712 Ataxin-2-like protein OS=Homo sapiens OX=9606 GN=ATXN2L PE=1 SV=2 4.53 1763.9 - 288526 - - - 2.1485 - 1.576 0.213 - 374.1 1 2 0 0.0024 9 0 0 0 1.18E+08 6.41E+07 - - - 1.9295 0.9998 221125_WJC_METTL3_EV_vs_WT_F05.07093.07093.2 4.08E-05 14-Aug R.DGYSYGSR.S "sp|Q13247|SRSF6_HUMAN,tr|A0A590UK80|A0A590UK80_HUMAN,tr|A0A590UJK4|A0A590UJK4_HUMAN,tr|A0A590UJP7|A0A590UJP7_HUMAN,tr|A0A590UK01|A0A590UK01_HUMAN" 5 903.3723 1.15 60258 7093 2 903.371242 452.6934 Serine\arginine-rich splicing factor 6 OS=Homo sapiens OX=9606 GN=SRSF6 PE=1 SV=2 5.83 1764.3 - 925668 - - - -1.1269 - 1.353 0.587 - 190.8 1 2 0 -0.001 8 0 0 0 3.18E+07 2.77E+07 - - - 4.2881 0.9992 221125_WJC_METTL3_EV_vs_WT_F05.07101.07101.2 2.09 16-Aug R.VNLVSGHVK.T "sp|P61962|DCAF7_HUMAN,tr|A0A087WWI6|A0A087WWI6_HUMAN" 2 951.5502 1.27 60264 7101 2 951.54982 476.7824 DDB1- and CUL4-associated factor 7 OS=Homo sapiens OX=9606 GN=DCAF7 PE=1 SV=1 8.73 1765.4 - 3.92E+06 - - - -0.3626 - 1.732 0.26 - 243.9 1 2 0 -0.0003 9 0 0 0 6.40E+07 5.04E+07 - - - 2.5503 0.998 221125_WJC_METTL3_EV_vs_WT_F05.07107.07107.2 0.544 14-Aug R.STLEPVEK[136.11].A "sp|P48741|HSP77_HUMAN,sp|P0DMV8|HS71A_HUMAN,sp|P0DMV9|HS71B_HUMAN,sp|P17066|HSP76_HUMAN,tr|V9GZ37|V9GZ37_HUMAN,tr|A0A0G2JIW1|A0A0G2JIW1_HUMAN" 6 909.4899 0.09 60268 7107 2 909.491305 455.7522 Putative heat shock 70 kDa protein 7 OS=Homo sapiens OX=9606 GN=HSPA7 PE=5 SV=2 4.53 1766.1 - 1.95E+06 - - - 1.5855 - 1.846 0.188 - 344.9 1 2 0 0.0014 8 0 0 0 1.46E+07 1.71E+08 - - - 2.278 0.9842 221125_WJC_METTL3_EV_vs_WT_F05.07109.07109.2 0.336 12-Jul K.KAGEIWK.G "sp|Q08945|SSRP1_HUMAN,tr|A0A0U1RRK2|A0A0U1RRK2_HUMAN" 2 830.465 0.77 60270 7109 2 830.465299 416.2398 FACT complex subunit SSRP1 OS=Homo sapiens OX=9606 GN=SSRP1 PE=1 SV=1 8.59 1766.3 - 469419 - - - 0.3143 - 1.448 0.017 - 174.3 1 2 0 0.0003 7 0 0 0 1.15E+07 1.48E+07 - - - 0.3394 0.9995 221125_WJC_METTL3_EV_vs_WT_F05.07110.07110.2 0.00177 20-Aug K.LC[160.03]VQNSPQEAR.N "sp|P33240|CSTF2_HUMAN,tr|A0A0A0MT56|A0A0A0MT56_HUMAN,tr|E9PID8|E9PID8_HUMAN,tr|E7EWR4|E7EWR4_HUMAN" 4 1300.6194 0.43 60271 7110 2 1300.621353 651.317 Cleavage stimulation factor subunit 2 OS=Homo sapiens OX=9606 GN=CSTF2 PE=1 SV=1 5.99 1766.4 - 224092 - - - 1.5139 - 1.826 0.393 - 241.8 1 2 0 0.002 11 0 0 0 6.57E+06 1.52E+07 - - - 3.572 0.9067 221125_WJC_METTL3_EV_vs_WT_F05.07113.07113.2 2.14 14-Jul K.SRLDQELK.L "sp|P46781|RS9_HUMAN,tr|C9JM19|C9JM19_HUMAN,tr|B5MCT8|B5MCT8_HUMAN,tr|F2Z3C0|F2Z3C0_HUMAN,tr|A8MXK4|A8MXK4_HUMAN" 5 987.5349 1.45 60272 7113 2 987.534413 494.7747 40S ribosomal protein S9 OS=Homo sapiens OX=9606 GN=RPS9 PE=1 SV=3 5.79 1766.8 - 1.89E+06 - - - -0.5023 - 1.405 0.086 - 243.5 1 2 1 -0.0005 8 0 0 0 1.29E+08 8.84E+07 - - - 0.7016 0.9809 221125_WJC_METTL3_EV_vs_WT_F05.07115.07115.2 0.00711 22-Nov C.GIGGGIGGGSSR.L "sp|P02533|K1C14_HUMAN,sp|P08779|K1C16_HUMAN,tr|K7ENV3|K7ENV3_HUMAN" 3 973.4941 0.48 60274 7115 2 973.494984 487.7543 "Keratin, type I cytoskeletal 14 OS=Homo sapiens OX=9606 GN=KRT14 PE=1 SV=4" 9.75 1767 - 2.02E+06 - - - 0.9009 - 1.822 0.426 - 291.4 1 1 0 0.0009 12 0 0 0 6.09E+07 1.27E+08 - - - 3.7657 0.9974 221125_WJC_METTL3_EV_vs_WT_F05.07118.07118.2 0.0115 18-Jun K.LLTEDSENQR.L sp|O00716|E2F3_HUMAN 1 1203.5731 2.33 60277 7118 2 1203.574261 602.7938 Transcription factor E2F3 OS=Homo sapiens OX=9606 GN=E2F3 PE=1 SV=1 4.14 1767.4 - 204884 - - - 0.9272 - 1.248 0.285 - 123.6 1 2 0 0.0011 10 0 0 0 1.88E+06 8.06E+05 - - - 1.7641 0.9989 221125_WJC_METTL3_EV_vs_WT_F05.07119.07119.2 0.11 24-Aug K.TDAEATDTEATET.- sp|Q9Y3D3|RT16_HUMAN 1 1353.542 - 60278 7119 2 1353.544845 677.7783 "28S ribosomal protein S16, mitochondrial OS=Homo sapiens OX=9606 GN=MRPS16 PE=1 SV=1" 3.39 1767.5 - 198909 - - - 2.1285 - 1.48 0.417 - 130.9 1 2 0 0.0029 13 0 0 0 - - - - - 3.1262 0.9552 221125_WJC_METTL3_EV_vs_WT_F05.07123.07123.2 0.322 12-Jul K.HIEVEVR.K "sp|Q9H8H0|NOL11_HUMAN,tr|J3QR28|J3QR28_HUMAN" 2 880.4767 1.63 60280 7123 2 880.476582 441.2456 Nucleolar protein 11 OS=Homo sapiens OX=9606 GN=NOL11 PE=1 SV=1 5.4 1768 - 2.06E+06 - - - -0.0954 - 1.204 0 - 174.7 1 2 0 -0.0001 7 0 0 0 4.72E+07 2.90E+07 - - - -0.3708 0.9983 221125_WJC_METTL3_EV_vs_WT_F05.07124.07124.2 1.43 12-Aug K.K[136.11]AGEIWK[136.11].G "sp|Q08945|SSRP1_HUMAN,tr|A0A0U1RRK2|A0A0U1RRK2_HUMAN" 2 846.4934 3.92 60281 7124 2 846.492612 424.254 FACT complex subunit SSRP1 OS=Homo sapiens OX=9606 GN=SSRP1 PE=1 SV=1 8.59 1768.1 - 774256 - - - -0.9758 - 1.686 0.183 - 207.4 1 2 0 -0.0008 7 0 0 0 6.91E+07 1.76E+07 - - - 2.0475 0.9997 221125_WJC_METTL3_EV_vs_WT_F05.07125.07125.2 0.0248 14-Aug K.C[160.03]EFDGC[160.03]DR.K sp|Q96T25|ZIC5_HUMAN 1 1057.3593 2.35 60282 7125 2 1057.35979 529.6869 Zinc finger protein ZIC 5 OS=Homo sapiens OX=9606 GN=ZIC5 PE=1 SV=2 4.03 1768.2 - 284564 - - - 0.435 - 1.704 0.405 - 354.4 1 2 0 0.0005 8 0 0 0 7.58E+06 3.23E+06 - - - 3.6396 0.9998 221125_WJC_METTL3_EV_vs_WT_F05.07126.07126.2 0.000136 20-Oct K.MASSENGTNFR.F sp|Q9NSC2|SALL1_HUMAN 1 1212.5193 2.9 60283 7126 2 1212.517154 607.2669 Sal-like protein 1 OS=Homo sapiens OX=9606 GN=SALL1 PE=1 SV=2 5.75 1768.4 - 233848 - - - -1.7987 - 2.126 0.598 - 426.9 1 2 0 -0.0022 11 0 0 0 3.87E+06 1.33E+06 - - - 5.4975 0.9976 221125_WJC_METTL3_EV_vs_WT_F05.07129.07129.2 0.314 14-Jul R.GPGPLQER.S "sp|P43243|MATR3_HUMAN,tr|A8MXP9|A8MXP9_HUMAN,tr|D6R991|D6R991_HUMAN,tr|A0A0R4J2E8|A0A0R4J2E8_HUMAN,tr|H0Y8T4|H0Y8T4_HUMAN,tr|D6REM6|D6REM6_HUMAN" 6 852.4454 1.49 60284 7129 2 852.445966 427.23 Matrin-3 OS=Homo sapiens OX=9606 GN=MATR3 PE=1 SV=2 6 1768.8 - 1.29E+06 - - - 0.7039 - 1.42 0.225 - 196.7 1 2 0 0.0006 8 0 0 0 2.59E+07 1.74E+07 - - - 1.7602 0.9734 221125_WJC_METTL3_EV_vs_WT_F05.07130.07130.2 0.000343 12-Aug R.YNGLIHR.K "sp|P46779|RL28_HUMAN,tr|H0YMF4|H0YMF4_HUMAN,tr|H0YLP6|H0YLP6_HUMAN,tr|H0YKD8|H0YKD8_HUMAN" 4 871.4664 0.63 60285 7130 2 872.471192 436.7405 60S ribosomal protein L28 OS=Homo sapiens OX=9606 GN=RPL28 PE=1 SV=3 8.75 1768.9 - 714989 - - - 1152.9497 - 1.639 0.415 - 237.8 1 2 0 1.0048 7 0 0 0 2.40E+07 3.81E+07 - - - 3.3562 0.9988 221125_WJC_METTL3_EV_vs_WT_F05.07131.07131.2 3.10E-05 14-Aug R.LTWASHEK.M sp|P06702|S10A9_HUMAN 1 970.4872 101.27 60286 7131 2 970.48825 486.2509 Protein S100-A9 OS=Homo sapiens OX=9606 GN=S100A9 PE=1 SV=1 6.75 1769 - 1.88E+06 - - - 1.05 - 1.635 0.264 - 242.1 1 2 0 0.001 8 0 0 0 4.79E+08 4.73E+06 - - - 2.4734 0.9998 221125_WJC_METTL3_EV_vs_WT_F05.07133.07133.2 0.000556 22-Sep K.MIGQATAADQEK[136.11].N sp|Q13015|AF1Q_HUMAN 1 1269.6115 1.23 60288 7133 2 1269.611568 635.813 Protein AF1q OS=Homo sapiens OX=9606 GN=MLLT11 PE=1 SV=1 4.37 1769.2 - 384102 - - - 0.0922 - 1.752 0.523 - 167.8 1 2 0 0.0001 12 0 0 0 1.30E+07 1.06E+07 - - - 4.3793 0.9999 221125_WJC_METTL3_EV_vs_WT_F05.07142.07142.3 0.00119 Nov-40 K.LVSDSLSEHEK[136.11].N "sp|Q96KR1|ZFR_HUMAN,tr|H0Y8W1|H0Y8W1_HUMAN" 2 1250.6234 1.02 60295 7142 3 1250.62165 417.8817 Zinc finger RNA-binding protein OS=Homo sapiens OX=9606 GN=ZFR PE=1 SV=2 4.65 1770.2 - 734923 - - - -1.3961 - 2.115 0.454 - 167.3 1 2 0 -0.0017 11 0 0 0 3.25E+07 3.18E+07 - - - 5.7291 0.9984 221125_WJC_METTL3_EV_vs_WT_F05.07143.07143.2 0.0064 14-Jul K.DVPNSQLR.H sp|Q9Y5A9|YTHD2_HUMAN 1 927.4774 1.36 60296 7143 2 927.476819 464.746 YTH domain-containing family protein 2 OS=Homo sapiens OX=9606 GN=YTHDF2 PE=1 SV=2 5.84 1770.3 - 611570 - - - -0.62 - 1.246 0.312 - 207.9 1 2 0 -0.0006 8 0 0 0 1.22E+07 8.96E+06 - - - 2.0086 0.9997 221125_WJC_METTL3_EV_vs_WT_F05.07144.07144.2 0.000286 20-Oct K.AVSEEQQPALK[136.11].G "sp|Q8NE71|ABCF1_HUMAN,tr|Q5STZ8|Q5STZ8_HUMAN,tr|F5GYK6|F5GYK6_HUMAN,tr|A0A0G2JJB9|A0A0G2JJB9_HUMAN" 4 1206.6336 0.87 60297 7144 2 1206.634839 604.3241 ATP-binding cassette sub-family F member 1 OS=Homo sapiens OX=9606 GN=ABCF1 PE=1 SV=2 4.53 1770.5 - 289945 - - - 1.0542 - 1.797 0.437 - 261.9 1 2 0 0.0013 11 0 0 0 1.60E+08 1.83E+08 - - - 3.8539 0.9816 221125_WJC_METTL3_EV_vs_WT_F05.07147.07147.2 0.0345 14-May K.ELSDIAHR.L "sp|P04075|ALDOA_HUMAN,tr|H3BR04|H3BR04_HUMAN,tr|H3BMQ8|H3BMQ8_HUMAN,tr|H3BQN4|H3BQN4_HUMAN,tr|H3BUH7|H3BUH7_HUMAN,tr|J3KPS3|J3KPS3_HUMAN,tr|H3BPS8|H3BPS8_HUMAN" 7 939.4774 1.47 60299 7147 2 939.476836 470.746 Fructose-bisphosphate aldolase A OS=Homo sapiens OX=9606 GN=ALDOA PE=1 SV=2 5.32 1770.8 - 2.24E+06 - - - -0.5939 - 1.261 0.068 - 117.1 1 2 0 -0.0006 8 0 0 0 3.02E+07 2.06E+07 - - - 0.2425 0.984 221125_WJC_METTL3_EV_vs_WT_F05.07149.07149.2 0.00146 20-Aug K.K[136.11]GPGEVAGTVT.G "sp|Q86U44|MTA70_HUMAN,tr|F5H6D8|F5H6D8_HUMAN,tr|H0YFV6|H0YFV6_HUMAN,tr|B4DTN4|B4DTN4_HUMAN" 4 1022.5488 0.22 60300 7149 2 1022.548285 512.2817 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 6 1771 - 5.68E+06 - - - -0.4792 - 1.757 0.428 - 164.5 1 1 0 -0.0005 11 0 0 0 4.59E+07 2.08E+08 - - - 3.7267 0.9864 221125_WJC_METTL3_EV_vs_WT_F05.07151.07151.2 0.15 14-Jul K.ELSDIAHR[166.11].L "sp|P04075|ALDOA_HUMAN,tr|H3BR04|H3BR04_HUMAN,tr|H3BMQ8|H3BMQ8_HUMAN,tr|H3BQN4|H3BQN4_HUMAN,tr|H3BUH7|H3BUH7_HUMAN,tr|J3KPS3|J3KPS3_HUMAN,tr|H3BPS8|H3BPS8_HUMAN" 7 949.4857 1.45 60302 7151 2 949.486768 475.7501 Fructose-bisphosphate aldolase A OS=Homo sapiens OX=9606 GN=ALDOA PE=1 SV=2 5.32 1771.2 - 1.47E+06 - - - 1.1627 - 1.482 0.076 - 273.8 2 2 0 0.0011 8 0 0 0 3.04E+07 2.10E+07 - - - 0.654 1 221125_WJC_METTL3_EV_vs_WT_F05.07152.07152.3 3.23E-05 14/40 K.LVSDSLSEHEK.N "sp|Q96KR1|ZFR_HUMAN,tr|H0Y8W1|H0Y8W1_HUMAN" 2 1242.6092 1.06 60303 7152 3 1242.606959 415.2103 Zinc finger RNA-binding protein OS=Homo sapiens OX=9606 GN=ZFR PE=1 SV=2 4.65 1771.2 - 1.37E+06 - - - -1.8002 - 2.601 0.509 - 221.6 1 2 0 -0.0022 11 0 0 0 3.24E+07 3.06E+07 - - - 6.9298 0.9995 221125_WJC_METTL3_EV_vs_WT_F05.07153.07153.3 2.81E-05 15/40 K.LLDAESEDRPK.Q "sp|O95239|KIF4A_HUMAN,sp|Q2VIQ3|KIF4B_HUMAN" 2 1271.6357 0.47 60304 7153 3 1271.631322 424.8859 Chromosome-associated kinesin KIF4A OS=Homo sapiens OX=9606 GN=KIF4A PE=1 SV=3 4.32 1771.4 - 789463 - - - -3.4782 - 2.243 0.392 - 268.6 1 2 0 -0.0044 11 0 0 0 7.55E+06 1.62E+07 - - - 5.204 0.9996 221125_WJC_METTL3_EV_vs_WT_F05.07155.07155.2 0.00338 20-Oct K.AVSEEQQPALK.G "sp|Q8NE71|ABCF1_HUMAN,tr|Q5STZ8|Q5STZ8_HUMAN,tr|F5GYK6|F5GYK6_HUMAN,tr|A0A0G2JJB9|A0A0G2JJB9_HUMAN" 4 1198.6194 0.87 60306 7155 2 1198.617783 600.317 ATP-binding cassette sub-family F member 1 OS=Homo sapiens OX=9606 GN=ABCF1 PE=1 SV=2 4.53 1771.6 - 648676 - - - -1.3215 - 1.823 0.389 - 278 1 2 0 -0.0016 11 0 0 0 1.60E+08 1.83E+08 - - - 3.5381 0.9999 221125_WJC_METTL3_EV_vs_WT_F05.07156.07156.2 6.72E-06 20-Dec K.GPGLAVQSGDK.T sp|Q96PK6|RBM14_HUMAN 1 1027.5298 2.19 60307 7156 2 1027.528895 514.7722 RNA-binding protein 14 OS=Homo sapiens OX=9606 GN=RBM14 PE=1 SV=2 5.84 1771.8 - 583665 - - - -0.9041 - 2.215 0.561 - 606.6 1 2 0 -0.0009 11 0 0 0 4.73E+08 2.16E+08 - - - 5.3356 0.9934 221125_WJC_METTL3_EV_vs_WT_F05.07157.07157.2 0.502 14-Jul K.RLPTEYER.N "sp|P27448|MARK3_HUMAN,tr|A0A7I2V3I9|A0A7I2V3I9_HUMAN,tr|H0YIY6|H0YIY6_HUMAN,tr|A0A7I2V4G7|A0A7I2V4G7_HUMAN,tr|A0A7I2V2N8|A0A7I2V2N8_HUMAN,tr|H0YJI9|H0YJI9_HUMAN,tr|A0A7I2V409|A0A7I2V409_HUMAN,tr|A0A7I2V549|A0A7I2V549_HUMAN,tr|A0A7I2V602|A0A7I2V602_HUMAN,tr|A0A7I2V639|A0A7I2V639_HUMAN,tr|A0A7I2V2E3|A0A7I2V2E3_HUMAN,tr|J3KNR0|J3KNR0_HUMAN" 12 1062.5458 0.24 60308 7157 2 1062.546556 532.2802 MAP\microtubule affinity-regulating kinase 3 OS=Homo sapiens OX=9606 GN=MARK3 PE=1 SV=5 6.14 1771.9 - 440097 - - - 0.704 - 1.402 0.129 - 112.6 1 2 0 0.0007 8 0 0 0 3.50E+06 1.43E+07 - - - 1.0126 0.9998 221125_WJC_METTL3_EV_vs_WT_F05.07162.07162.2 0.000205 14-Aug R.DSC[160.03]PLDC[160.03]K.V "sp|P84103|SRSF3_HUMAN,tr|A0A087X2D0|A0A087X2D0_HUMAN" 2 993.3896 1.26 60311 7162 2 993.388223 497.7021 Serine\arginine-rich splicing factor 3 OS=Homo sapiens OX=9606 GN=SRSF3 PE=1 SV=1 4.21 1772.4 - 6.08E+06 - - - -1.3529 - 1.617 0.517 - 297.8 1 2 0 -0.0013 8 0 0 0 1.30E+08 1.03E+08 - - - 4.3085 0.9996 221125_WJC_METTL3_EV_vs_WT_F05.07163.07163.2 0.00241 14-Aug R.DSC[160.03]PLDC[160.03]K[136.11].V "sp|P84103|SRSF3_HUMAN,tr|A0A087X2D0|A0A087X2D0_HUMAN" 2 1001.4038 1.26 60312 7163 2 1001.402226 501.7092 Serine\arginine-rich splicing factor 3 OS=Homo sapiens OX=9606 GN=SRSF3 PE=1 SV=1 4.21 1772.5 - 5.48E+06 - - - -1.5388 - 1.551 0.478 - 285.7 1 2 0 -0.0015 8 0 0 0 1.30E+08 1.03E+08 - - - 3.8947 0.9998 221125_WJC_METTL3_EV_vs_WT_F05.07166.07166.2 0.000534 13/20 K.GPGLAVQSGDK[136.11].T sp|Q96PK6|RBM14_HUMAN 1 1035.544 2.19 60315 7166 2 1035.542336 518.7793 RNA-binding protein 14 OS=Homo sapiens OX=9606 GN=RBM14 PE=1 SV=2 5.84 1772.8 - 1.09E+06 - - - -1.6301 - 2.22 0.48 - 767.7 1 2 0 -0.0017 11 0 0 0 4.73E+08 2.16E+08 - - - 4.7432 0.9949 221125_WJC_METTL3_EV_vs_WT_F05.07169.07169.2 0.094 16-Aug R.ALVPDSVKK.E sp|Q9NPA8|ENY2_HUMAN 1 955.5702 1.78 60318 7169 2 955.568281 478.7924 Transcription and mRNA export factor ENY2 OS=Homo sapiens OX=9606 GN=ENY2 PE=1 SV=1 8.64 1773.1 - 794134 - - - -2.0417 - 1.502 0.198 - 236.4 1 2 0 -0.002 9 0 0 0 6.94E+07 3.90E+07 - - - 1.6797 0.9991 221125_WJC_METTL3_EV_vs_WT_F05.07170.07170.2 0.000163 18-Sep K.GMTENEVEDR[166.11].L "sp|Q13617|CUL2_HUMAN,tr|Q5T2B5|Q5T2B5_HUMAN,tr|A0A0A0MTN0|A0A0A0MTN0_HUMAN" 3 1188.4956 0.35 60319 7170 2 1188.499398 595.2551 Cullin-2 OS=Homo sapiens OX=9606 GN=CUL2 PE=1 SV=2 4 1773.2 - 493438 - - - 3.1645 - 1.982 0.45 - 401.5 1 2 0 0.0038 10 0 0 0 2.47E+06 7.07E+06 - - - 4.2731 0.9998 221125_WJC_METTL3_EV_vs_WT_F05.07174.07174.2 0.00185 18-Sep K.IITQQVQPSK[136.11].L "sp|Q7Z589|EMSY_HUMAN,tr|E9PPE6|E9PPE6_HUMAN,tr|E9PMC9|E9PMC9_HUMAN" 3 1148.6645 0.82 60321 7174 2 1148.664101 575.3395 BRCA2-interacting transcriptional repressor EMSY OS=Homo sapiens OX=9606 GN=EMSY PE=1 SV=2 8.75 1773.7 - 1.09E+06 - - - -0.3239 - 2.083 0.44 - 203.8 1 2 0 -0.0004 10 0 0 0 3.50E+07 4.29E+07 - - - 4.339 0.9998 221125_WJC_METTL3_EV_vs_WT_F05.07175.07175.2 0.053 20-Dec K.GAVIVVSHDAR.L "sp|Q8NE71|ABCF1_HUMAN,tr|A0A0G2JIC2|A0A0G2JIC2_HUMAN,tr|Q5STZ8|Q5STZ8_HUMAN,tr|H0YGW7|H0YGW7_HUMAN" 4 1122.6146 0.51 60322 7175 2 1122.613835 562.3146 ATP-binding cassette sub-family F member 1 OS=Homo sapiens OX=9606 GN=ABCF1 PE=1 SV=2 6.74 1773.9 - 1.18E+06 - - - -0.6423 - 2.668 0.325 - 736.6 1 2 0 -0.0007 11 0 0 0 2.23E+07 4.40E+07 - - - 4.096 0.9996 221125_WJC_METTL3_EV_vs_WT_F05.07178.07178.3 0.00524 Dec-36 K.GLYNEHTVDR[166.11].A sp|Q6P6C2|ALKB5_HUMAN 1 1212.5763 1.05 60324 7178 3 1212.571714 405.1994 RNA demethylase ALKBH5 OS=Homo sapiens OX=9606 GN=ALKBH5 PE=1 SV=2 5.32 1774.2 - 1.30E+06 - - - -3.7573 - 2.574 0.391 - 210.2 1 2 0 -0.0046 10 0 0 0 3.67E+07 3.51E+07 - - - 5.6592 0.996 221125_WJC_METTL3_EV_vs_WT_F05.07180.07180.2 0.0912 18-Aug K.NAEQAATQLK.V sp|Q86UP2|KTN1_HUMAN 1 1072.5513 2.64 60325 7180 2 1072.550191 537.2829 Kinectin OS=Homo sapiens OX=9606 GN=KTN1 PE=1 SV=1 6 1774.4 - 3.44E+06 - - - -1.0219 - 1.568 0.151 - 243.5 1 2 0 -0.0011 10 0 0 0 1.91E+08 7.24E+07 - - - 1.4115 0.9937 221125_WJC_METTL3_EV_vs_WT_F05.07181.07181.2 0.00424 20-Dec A.LEEANNDLENK.L sp|P35527|K1C9_HUMAN 1 1287.5943 78.6 60326 7181 2 1287.593322 644.8044 "Keratin, type I cytoskeletal 9 OS=Homo sapiens OX=9606 GN=KRT9 PE=1 SV=3" 4 1774.5 - 1.03E+06 - - - -0.7394 - 2.472 0.515 - 382.3 1 1 0 -0.001 11 0 0 0 4.85E+07 6.17E+05 - - - 5.2928 0.9981 221125_WJC_METTL3_EV_vs_WT_F05.07182.07182.2 0.0618 18-Oct K.NAEQAATQLK[136.11].V sp|Q86UP2|KTN1_HUMAN 1 1080.5655 2.56 60327 7182 2 1080.566355 541.29 Kinectin OS=Homo sapiens OX=9606 GN=KTN1 PE=1 SV=1 6 1774.6 - 1.99E+06 - - - 0.8033 - 1.354 0.282 - 301.2 1 2 0 0.0009 10 0 0 0 1.88E+08 7.34E+07 - - - 1.9695 0.9961 221125_WJC_METTL3_EV_vs_WT_F05.07183.07183.2 0.0599 16-Jul R.FSTPEQAAK[136.11].N "sp|P14866|HNRPL_HUMAN,tr|M0QYT0|M0QYT0_HUMAN,tr|A0A3B3ITJ4|A0A3B3ITJ4_HUMAN,tr|M0QXS5|M0QXS5_HUMAN" 4 985.496 1.04 60328 7183 2 985.4934 493.7553 Heterogeneous nuclear ribonucleoprotein L OS=Homo sapiens OX=9606 GN=HNRNPL PE=1 SV=2 6 1774.7 - 1.94E+06 - - - -2.6494 - 1.48 0.282 - 114.9 1 2 0 -0.0026 9 0 0 0 1.18E+08 1.14E+08 - - - 2.2572 0.9997 221125_WJC_METTL3_EV_vs_WT_F05.07185.07185.3 0.000598 Nov-36 K.GLYNEHTVDR.A sp|Q6P6C2|ALKB5_HUMAN 1 1202.568 1.05 60330 7185 3 1202.563893 401.8633 RNA demethylase ALKBH5 OS=Homo sapiens OX=9606 GN=ALKBH5 PE=1 SV=2 5.32 1774.9 - 1.21E+06 - - - -3.4152 - 2.226 0.426 - 159.5 1 2 0 -0.0041 10 0 0 0 3.67E+07 3.51E+07 - - - 5.6253 0.9839 221125_WJC_METTL3_EV_vs_WT_F05.07189.07189.2 0.000117 16-Oct K.NMQLTAGSK.L sp|O75934|SPF27_HUMAN 1 948.4699 1 60332 7189 2 948.463149 475.2422 Pre-mRNA-splicing factor SPF27 OS=Homo sapiens OX=9606 GN=BCAS2 PE=1 SV=1 8.75 1775.5 - 1.08E+06 - - - -7.0819 - 1.757 0.458 - 437.4 1 2 0 -0.0067 9 0 0 0 6.25E+07 6.27E+07 - - - 4.0522 0.7906 221125_WJC_METTL3_EV_vs_WT_F05.07191.07191.2 0.00294 14-Oct T.TTGHLIYK[136.11].C "sp|Q05639|EF1A2_HUMAN,sp|P68104|EF1A1_HUMAN,sp|Q5VTE0|EF1A3_HUMAN,tr|A0A2R8Y488|A0A2R8Y488_HUMAN,tr|A0A2R8YDN5|A0A2R8YDN5_HUMAN,tr|A0A7I2V659|A0A7I2V659_HUMAN,tr|A0A7I2V3H3|A0A7I2V3H3_HUMAN,tr|Q5JR01|Q5JR01_HUMAN,tr|A0A2U3TZH3|A0A2U3TZH3_HUMAN,tr|A0A7I2V5N4|A0A7I2V5N4_HUMAN,tr|A0A087WVQ9|A0A087WVQ9_HUMAN,tr|A6PW80|A6PW80_HUMAN,tr|A0A087WV01|A0A087WV01_HUMAN,tr|A0A2R8Y660|A0A2R8Y660_HUMAN,tr|A0A6Q8PFK6|A0A6Q8PFK6_HUMAN" 15 939.5269 5.49 60334 7191 2 939.522822 470.7707 Elongation factor 1-alpha 2 OS=Homo sapiens OX=9606 GN=EEF1A2 PE=1 SV=1 8.29 1775.7 - 1.08E+06 - - - -4.3586 - 2.034 0.295 - 552.6 1 1 0 -0.0041 8 0 0 0 1.16E+09 2.11E+08 - - - 3.3599 0.7742 221125_WJC_METTL3_EV_vs_WT_F05.07193.07193.2 0.315 12-Jun R.ITHGFQL.K "sp|Q96LI5|CNO6L_HUMAN,tr|H0Y9Z5|H0Y9Z5_HUMAN" 2 814.4337 - 60336 7193 2 814.433599 408.2241 CCR4-NOT transcription complex subunit 6-like OS=Homo sapiens OX=9606 GN=CNOT6L PE=1 SV=2 6.74 1776 - 580722 - - - -0.1707 - 1.139 0.226 - 84.3 1 1 0 -0.0001 7 0 0 0 - - - - - 1.1226 0.9997 221125_WJC_METTL3_EV_vs_WT_F05.07197.07197.2 0.000658 18-Nov K.STTTGHLIYK[136.11].C "sp|Q05639|EF1A2_HUMAN,sp|P68104|EF1A1_HUMAN,sp|Q5VTE0|EF1A3_HUMAN,tr|A0A2R8Y488|A0A2R8Y488_HUMAN,tr|A0A2R8YDN5|A0A2R8YDN5_HUMAN,tr|A0A7I2V659|A0A7I2V659_HUMAN,tr|A0A7I2V3H3|A0A7I2V3H3_HUMAN,tr|Q5JR01|Q5JR01_HUMAN,tr|A0A2U3TZH3|A0A2U3TZH3_HUMAN,tr|A0A7I2V5N4|A0A7I2V5N4_HUMAN,tr|A0A087WVQ9|A0A087WVQ9_HUMAN,tr|A6PW80|A6PW80_HUMAN,tr|A0A087WV01|A0A087WV01_HUMAN,tr|A0A2R8Y660|A0A2R8Y660_HUMAN,tr|A0A6Q8PFK6|A0A6Q8PFK6_HUMAN" 15 1127.6066 0.37 60338 7197 2 1127.604172 564.8106 Elongation factor 1-alpha 2 OS=Homo sapiens OX=9606 GN=EEF1A2 PE=1 SV=1 8.33 1776.5 - 7.02E+06 - - - -2.1745 - 2.429 0.467 - 659 1 2 0 -0.0025 10 0 0 0 2.63E+08 7.18E+08 - - - 4.9667 0.9822 221125_WJC_METTL3_EV_vs_WT_F05.07198.07198.2 0.032 14-Dec R.GRLDSELR.N "sp|P48668|K2C6C_HUMAN,sp|P04259|K2C6B_HUMAN,sp|P13647|K2C5_HUMAN,sp|Q5XKE5|K2C79_HUMAN,sp|P02538|K2C6A_HUMAN,tr|F8W0C6|F8W0C6_HUMAN" 6 944.5039 229.33 60339 7198 2 944.501822 473.2592 "Keratin, type II cytoskeletal 6C OS=Homo sapiens OX=9606 GN=KRT6C PE=1 SV=3" 6.07 1776.6 - 2.74E+06 - - - -2.2456 - 2.129 0.2 - 553.8 1 2 1 -0.0021 8 0 0 0 7.63E+09 3.33E+07 - - - 2.7965 0.8562 221125_WJC_METTL3_EV_vs_WT_F05.07199.07199.2 0.146 14-Jun K.GTDYQLSK[136.11].E "sp|P54577|SYYC_HUMAN,tr|A0A6Q8PFX4|A0A6Q8PFX4_HUMAN,tr|A0A6Q8PF15|A0A6Q8PF15_HUMAN,tr|A0A0C4DGZ5|A0A0C4DGZ5_HUMAN,tr|A0A6Q8PFX2|A0A6Q8PFX2_HUMAN,tr|A0A6Q8PFC1|A0A6Q8PFC1_HUMAN" 6 918.4538 0.69 60340 7199 2 918.44783 460.2342 "Tyrosine--tRNA ligase, cytoplasmic OS=Homo sapiens OX=9606 GN=YARS1 PE=1 SV=4" 5.83 1776.7 - 1.84E+06 - - - -6.5131 - 1.287 0.226 - 120.3 1 2 0 -0.006 8 0 0 0 7.24E+07 1.05E+08 - - - 1.4693 0.9995 221125_WJC_METTL3_EV_vs_WT_F05.07200.07200.2 0.00383 18-Sep K.STTTGHLIYK.C "sp|Q05639|EF1A2_HUMAN,sp|P68104|EF1A1_HUMAN,sp|Q5VTE0|EF1A3_HUMAN,tr|A0A2R8Y488|A0A2R8Y488_HUMAN,tr|A0A2R8YDN5|A0A2R8YDN5_HUMAN,tr|A0A7I2V659|A0A7I2V659_HUMAN,tr|A0A7I2V3H3|A0A7I2V3H3_HUMAN,tr|Q5JR01|Q5JR01_HUMAN,tr|A0A2U3TZH3|A0A2U3TZH3_HUMAN,tr|A0A7I2V5N4|A0A7I2V5N4_HUMAN,tr|A0A087WVQ9|A0A087WVQ9_HUMAN,tr|A6PW80|A6PW80_HUMAN,tr|A0A087WV01|A0A087WV01_HUMAN,tr|A0A2R8Y660|A0A2R8Y660_HUMAN,tr|A0A6Q8PFK6|A0A6Q8PFK6_HUMAN" 15 1119.5924 0.37 60341 7200 2 1119.589975 560.8035 Elongation factor 1-alpha 2 OS=Homo sapiens OX=9606 GN=EEF1A2 PE=1 SV=1 8.33 1776.7 - 1.82E+06 - - - -2.1874 - 2.119 0.409 - 362.3 1 2 0 -0.0024 10 0 0 0 2.63E+08 7.18E+08 - - - 4.1572 0.9853 221125_WJC_METTL3_EV_vs_WT_F05.07202.07202.2 0.0448 16-Nov K.IREYEQTLK.N "sp|Q13948|CASP_HUMAN,sp|P39880|CUX1_HUMAN,tr|A0A2R8Y8D0|A0A2R8Y8D0_HUMAN,tr|A0A2R8Y852|A0A2R8Y852_HUMAN,tr|A0A2R8YDI1|A0A2R8YDI1_HUMAN" 5 1178.6295 1.7 60343 7202 2 1178.62802 590.322 Protein CASP OS=Homo sapiens OX=9606 GN=CUX1 PE=1 SV=2 6.14 1776.9 - 704841 - - - -1.2879 - 2.108 0.163 - 506.2 1 2 1 -0.0015 9 0 0 0 4.98E+07 2.93E+07 - - - 2.4019 0.9982 221125_WJC_METTL3_EV_vs_WT_F05.07206.07206.2 0.0483 14-Jul K.GTDYQLSK.E "sp|P54577|SYYC_HUMAN,tr|A0A6Q8PFX4|A0A6Q8PFX4_HUMAN,tr|A0A6Q8PF15|A0A6Q8PF15_HUMAN,tr|A0A0C4DGZ5|A0A0C4DGZ5_HUMAN,tr|A0A6Q8PFX2|A0A6Q8PFX2_HUMAN,tr|A0A6Q8PFC1|A0A6Q8PFC1_HUMAN" 6 910.4396 0.69 60345 7206 2 910.43839 456.2271 "Tyrosine--tRNA ligase, cytoplasmic OS=Homo sapiens OX=9606 GN=YARS1 PE=1 SV=4" 5.83 1777.4 - 1.59E+06 - - - -1.3422 - 1.434 0.273 - 164.9 1 2 0 -0.0012 8 0 0 0 7.24E+07 1.05E+08 - - - 2.1441 0.9712 221125_WJC_METTL3_EV_vs_WT_F05.07207.07207.2 0.000221 16-Dec S.TTTGHLIYK[136.11].C "sp|Q05639|EF1A2_HUMAN,sp|P68104|EF1A1_HUMAN,sp|Q5VTE0|EF1A3_HUMAN,tr|A0A2R8Y488|A0A2R8Y488_HUMAN,tr|A0A2R8YDN5|A0A2R8YDN5_HUMAN,tr|A0A7I2V659|A0A7I2V659_HUMAN,tr|A0A7I2V3H3|A0A7I2V3H3_HUMAN,tr|Q5JR01|Q5JR01_HUMAN,tr|A0A2U3TZH3|A0A2U3TZH3_HUMAN,tr|A0A7I2V5N4|A0A7I2V5N4_HUMAN,tr|A0A087WVQ9|A0A087WVQ9_HUMAN,tr|A6PW80|A6PW80_HUMAN,tr|A0A087WV01|A0A087WV01_HUMAN,tr|A0A2R8Y660|A0A2R8Y660_HUMAN,tr|A0A6Q8PFK6|A0A6Q8PFK6_HUMAN" 15 1040.5746 0.39 60346 7207 2 1040.572069 521.2946 Elongation factor 1-alpha 2 OS=Homo sapiens OX=9606 GN=EEF1A2 PE=1 SV=1 8.29 1777.5 - 1.33E+06 - - - -2.4275 - 2.051 0.434 - 621.8 1 1 0 -0.0025 9 0 0 0 3.51E+07 9.10E+07 - - - 4.3239 0.9578 221125_WJC_METTL3_EV_vs_WT_F05.07208.07208.2 0.00128 12-Aug R.TGHWLNH.G sp|Q86U44|MTA70_HUMAN 1 863.4038 - 60347 7208 2 863.403421 432.7092 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 6.61 1777.7 - 728347 - - - -0.4795 - 1.366 0.358 - 215.2 1 1 0 -0.0004 7 0 0 0 - - - - - 2.6733 0.9992 221125_WJC_METTL3_EV_vs_WT_F05.07211.07211.2 0.00715 14-Aug K.QQNLPVTR.L "sp|Q8WVM8|SCFD1_HUMAN,tr|A0A7I2V4U2|A0A7I2V4U2_HUMAN,tr|A0A7I2V4B8|A0A7I2V4B8_HUMAN,tr|A0A7I2V5Z4|A0A7I2V5Z4_HUMAN,tr|B7Z5N7|B7Z5N7_HUMAN,tr|A0A7I2V5I2|A0A7I2V5I2_HUMAN,tr|A0A7I2V2U5|A0A7I2V2U5_HUMAN,tr|A0A7I2V448|A0A7I2V448_HUMAN,tr|A0A7I2V320|A0A7I2V320_HUMAN,tr|A0A7I2V3G4|A0A7I2V3G4_HUMAN,tr|A0A7I2V3B4|A0A7I2V3B4_HUMAN,tr|G3V2M8|G3V2M8_HUMAN,tr|A0A7I2V4R0|A0A7I2V4R0_HUMAN" 13 954.5247 1.18 60348 7211 2 954.52473 478.2696 Sec1 family domain-containing protein 1 OS=Homo sapiens OX=9606 GN=SCFD1 PE=1 SV=4 9.75 1778.1 - 2.34E+06 - - - 0.0534 - 1.389 0.346 - 293.7 1 2 0 0.0001 8 0 0 0 1.65E+08 1.40E+08 - - - 2.5875 0.9996 221125_WJC_METTL3_EV_vs_WT_F05.07215.07215.2 9.13E-06 20-Nov R.IPSTDTQVQPK[136.11].L "sp|Q9ULV3|CIZ1_HUMAN,tr|Q5SYW2|Q5SYW2_HUMAN,tr|F5H2X7|F5H2X7_HUMAN,tr|H0Y5D5|H0Y5D5_HUMAN,tr|A0A494C0L7|A0A494C0L7_HUMAN,tr|Q9BTG3|Q9BTG3_HUMAN" 6 1220.6492 2.88 60349 7215 2 1220.646277 611.3319 Cip1-interacting zinc finger protein OS=Homo sapiens OX=9606 GN=CIZ1 PE=1 SV=2 5.84 1778.6 - 311512 - - - -2.4086 - 1.868 0.53 - 360.6 1 2 0 -0.0029 11 0 0 0 5.93E+08 2.06E+08 - - - 4.6451 0.7853 221125_WJC_METTL3_EV_vs_WT_F05.07223.07223.2 5.79 16-Jul K.NMQLTAGSK[136.11].L sp|O75934|SPF27_HUMAN 1 956.4841 0.94 60352 7223 2 956.48595 479.2493 Pre-mRNA-splicing factor SPF27 OS=Homo sapiens OX=9606 GN=BCAS2 PE=1 SV=1 8.75 1779.6 - 3.56E+06 - - - 1.9697 - 0.963 0.035 - 128.6 2 2 0 0.0019 9 0 0 0 6.41E+07 6.84E+07 - - - -0.9446 0.9997 221125_WJC_METTL3_EV_vs_WT_F05.07225.07225.2 0.00296 20-Sep K.GGLYSQEQAAK.A "sp|Q9NVN8|GNL3L_HUMAN,tr|A0A6I8PL80|A0A6I8PL80_HUMAN,tr|A0A6I8PS19|A0A6I8PS19_HUMAN" 3 1150.5619 2.1 60353 7225 2 1150.561435 576.2882 Guanine nucleotide-binding protein-like 3-like protein OS=Homo sapiens OX=9606 GN=GNL3L PE=1 SV=1 6 1779.8 - 1.36E+06 - - - -0.3624 - 1.453 0.464 - 146 1 2 0 -0.0004 11 0 0 0 3.27E+07 1.56E+07 - - - 3.4787 0.9983 221125_WJC_METTL3_EV_vs_WT_F05.07226.07226.2 0.079 14-Jul R.YSQDSFSK.H "sp|O14966|RAB7L_HUMAN,tr|E9PL56|E9PL56_HUMAN" 2 960.4189 3.11 60354 7226 2 960.417943 481.2167 Ras-related protein Rab-7L1 OS=Homo sapiens OX=9606 GN=RAB29 PE=1 SV=1 5.83 1780 - 287796 - - - -0.9715 - 1.302 0.301 - 139.5 1 2 0 -0.0009 8 0 0 0 2.24E+07 7.21E+06 - - - 2.0598 0.8624 221125_WJC_METTL3_EV_vs_WT_F05.07240.07240.2 0.0139 14-Aug K.AQC[160.03]PIVER[166.11].L "sp|P46782|RS5_HUMAN,tr|M0R0F0|M0R0F0_HUMAN,tr|M0R0R2|M0R0R2_HUMAN" 3 981.4941 3.4 60359 7240 2 982.495267 491.7543 40S ribosomal protein S5 OS=Homo sapiens OX=9606 GN=RPS5 PE=1 SV=4 6.04 1781.8 - 1.00E+06 - - - 1020.0224 - 1.423 0.302 - 372.3 1 2 0 1.0011 8 0 0 0 3.14E+08 9.23E+07 - - - 2.0211 0.973 221125_WJC_METTL3_EV_vs_WT_F05.07242.07242.3 0.0284 Aug-32 K.IREYEQTLK.N "sp|Q13948|CASP_HUMAN,sp|P39880|CUX1_HUMAN,tr|A0A2R8Y8D0|A0A2R8Y8D0_HUMAN,tr|A0A2R8Y852|A0A2R8Y852_HUMAN,tr|A0A2R8YDI1|A0A2R8YDI1_HUMAN" 5 1178.6295 1.32 60360 7242 3 1178.628472 393.8838 Protein CASP OS=Homo sapiens OX=9606 GN=CUX1 PE=1 SV=2 6.14 1782 - 4.69E+06 - - - -0.9044 - 1.559 0.201 - 133.2 1 2 1 -0.0011 9 0 0 0 2.47E+08 1.87E+08 - - - 2.1189 0.7737 221125_WJC_METTL3_EV_vs_WT_F05.07248.07248.2 1.39 12-Sep V.RLDSELR.S "sp|Q86Y46|K2C73_HUMAN,sp|Q7RTS7|K2C74_HUMAN,sp|P48668|K2C6C_HUMAN,sp|Q3SY84|K2C71_HUMAN,sp|P04259|K2C6B_HUMAN,sp|P13647|K2C5_HUMAN,sp|Q14CN4|K2C72_HUMAN,sp|Q5XKE5|K2C79_HUMAN,sp|P02538|K2C6A_HUMAN,tr|F8W0C6|F8W0C6_HUMAN,tr|F8W1S1|F8W1S1_HUMAN" 11 887.4825 111.02 60363 7248 2 887.481268 444.7485 "Keratin, type II cytoskeletal 73 OS=Homo sapiens OX=9606 GN=KRT73 PE=1 SV=1" 6.07 1782.9 - 1.30E+06 - - - -1.3645 - 1.616 0.112 - 237.9 1 1 0 -0.0012 7 0 0 0 5.17E+07 4.66E+05 - - - 1.3886 0.9981 221125_WJC_METTL3_EV_vs_WT_F05.07250.07250.2 0.021 16-Aug R.FSTPEQAAK.N "sp|P14866|HNRPL_HUMAN,tr|M0QYT0|M0QYT0_HUMAN,tr|A0A3B3ITJ4|A0A3B3ITJ4_HUMAN,tr|M0QXS5|M0QXS5_HUMAN" 4 977.4818 0.35 60364 7250 2 977.482088 489.7482 Heterogeneous nuclear ribonucleoprotein L OS=Homo sapiens OX=9606 GN=HNRNPL PE=1 SV=2 6 1783.1 - 1.62E+06 - - - 0.2834 - 1.376 0.254 - 186.2 1 2 0 0.0003 9 0 0 0 1.26E+08 3.58E+08 - - - 1.8404 0.9993 221125_WJC_METTL3_EV_vs_WT_F05.07257.07257.2 0.00187 14-Sep K.QQNLPVTR[166.11].L "sp|Q8WVM8|SCFD1_HUMAN,tr|A0A7I2V4U2|A0A7I2V4U2_HUMAN,tr|A0A7I2V4B8|A0A7I2V4B8_HUMAN,tr|A0A7I2V5Z4|A0A7I2V5Z4_HUMAN,tr|B7Z5N7|B7Z5N7_HUMAN,tr|A0A7I2V5I2|A0A7I2V5I2_HUMAN,tr|A0A7I2V2U5|A0A7I2V2U5_HUMAN,tr|A0A7I2V448|A0A7I2V448_HUMAN,tr|A0A7I2V320|A0A7I2V320_HUMAN,tr|A0A7I2V3G4|A0A7I2V3G4_HUMAN,tr|A0A7I2V3B4|A0A7I2V3B4_HUMAN,tr|G3V2M8|G3V2M8_HUMAN,tr|A0A7I2V4R0|A0A7I2V4R0_HUMAN" 13 964.5329 1.18 60368 7257 2 964.531075 483.2738 Sec1 family domain-containing protein 1 OS=Homo sapiens OX=9606 GN=SCFD1 PE=1 SV=4 9.75 1784 - 2.71E+06 - - - -1.9429 - 1.741 0.367 - 378.7 1 2 0 -0.0019 8 0 0 0 1.68E+08 1.41E+08 - - - 3.4233 0.9999 221125_WJC_METTL3_EV_vs_WT_F05.07262.07262.2 1.73E-05 22-Sep R.ELTNQQEASVER.Q "sp|Q14203|DCTN1_HUMAN,tr|A0A804CDA6|A0A804CDA6_HUMAN,tr|E7EX90|E7EX90_HUMAN,tr|A0A7P0Z4C3|A0A7P0Z4C3_HUMAN,tr|Q6AWB1|Q6AWB1_HUMAN" 5 1402.6688 2.16 60371 7262 2 1402.668884 702.3417 Dynactin subunit 1 OS=Homo sapiens OX=9606 GN=DCTN1 PE=1 SV=3 4.25 1784.5 - 227043 - - - 0.0342 - 2.18 0.52 - 336.4 1 2 0 0 12 0 0 0 1.40E+07 6.49E+06 - - - 4.9322 0.9995 221125_WJC_METTL3_EV_vs_WT_F05.07264.07264.2 0.0731 14-Sep R.VAIEHLDK[136.11].L "sp|P48643|TCPE_HUMAN,tr|E9PCA1|E9PCA1_HUMAN,tr|B7ZAR1|B7ZAR1_HUMAN,tr|E7ENZ3|E7ENZ3_HUMAN" 4 931.5218 0.6 60372 7264 2 931.520904 466.7682 T-complex protein 1 subunit epsilon OS=Homo sapiens OX=9606 GN=CCT5 PE=1 SV=1 5.32 1784.8 - 2.66E+07 - - - -0.9962 - 1.786 0.317 - 262.5 1 2 0 -0.0009 8 0 0 0 6.68E+08 1.11E+09 - - - 3.1313 0.9996 221125_WJC_METTL3_EV_vs_WT_F05.07266.07266.2 0.00498 18-Sep R.GLQEGYENSR.C "sp|Q9C0C9|UBE2O_HUMAN,tr|K7ES11|K7ES11_HUMAN" 2 1151.5207 0.86 60373 7266 2 1151.519919 576.7676 (E3-independent) E2 ubiquitin-conjugating enzyme OS=Homo sapiens OX=9606 GN=UBE2O PE=1 SV=3 4.53 1785 - 236363 - - - -0.6921 - 1.428 0.433 - 245.4 1 2 0 -0.0008 10 0 0 0 1.01E+07 1.17E+07 - - - 3.2334 0.9998 221125_WJC_METTL3_EV_vs_WT_F05.07276.07276.2 2.40E-06 20-Nov R.VADNAQQQYVR.S sp|Q8TDD1|DDX54_HUMAN 1 1290.6317 2.16 60376 7276 2 1290.629706 646.3231 ATP-dependent RNA helicase DDX54 OS=Homo sapiens OX=9606 GN=DDX54 PE=1 SV=2 5.81 1786.3 - 167662 - - - -1.5163 - 2.434 0.515 - 716.1 1 2 0 -0.002 11 0 0 0 4.82E+06 2.23E+06 - - - 5.2506 0.9997 221125_WJC_METTL3_EV_vs_WT_F05.07280.07280.2 0.00105 12-Oct K.HLESFPK.Q sp|Q92665|RT31_HUMAN 1 856.4443 1.34 60378 7280 2 856.444146 429.2294 "28S ribosomal protein S31, mitochondrial OS=Homo sapiens OX=9606 GN=MRPS31 PE=1 SV=3" 6.75 1786.8 - 1.11E+06 - - - -0.1833 - 1.649 0.38 - 434 1 2 0 -0.0002 7 0 0 0 4.51E+07 3.38E+07 - - - 3.4324 0.9998 221125_WJC_METTL3_EV_vs_WT_F05.07282.07282.2 0.000285 22-Nov R.GSSLGAGNVADR.V "sp|Q8NB90|AFG2H_HUMAN,tr|A0A6Q8PGU6|A0A6Q8PGU6_HUMAN" 2 1102.5367 1.65 60379 7282 2 1102.537047 552.2756 ATPase family protein 2 homolog OS=Homo sapiens OX=9606 GN=SPATA5 PE=1 SV=3 5.84 1787 - 674859 - - - 0.3147 - 2.127 0.41 - 365.6 1 2 0 0.0003 12 0 0 0 1.62E+07 9.81E+06 - - - 4.0549 0.9996 221125_WJC_METTL3_EV_vs_WT_F05.07285.07285.2 0.000511 16-Aug K.VSSPDYPER.N sp|O60825|F262_HUMAN 1 1048.4825 2.38 60381 7285 2 1048.481061 525.2485 "6-phosphofructo-2-kinase\fructose-2,6-bisphosphatase 2 OS=Homo sapiens OX=9606 GN=PFKFB2 PE=1 SV=2" 4.37 1787.3 - 1.34E+06 - - - -1.4097 - 1.693 0.409 - 265.5 1 2 0 -0.0015 9 0 0 0 5.58E+07 2.34E+07 - - - 3.5846 0.9976 221125_WJC_METTL3_EV_vs_WT_F05.07291.07291.3 0.00102 Oct-32 K.LVEQLK[136.11]EER[166.11].E "sp|O95232|LC7L3_HUMAN,tr|J3KPP4|J3KPP4_HUMAN" 2 1160.652 1.07 60385 7291 3 1160.649726 387.8913 Luc7-like protein 3 OS=Homo sapiens OX=9606 GN=LUC7L3 PE=1 SV=2 4.79 1788.1 - 2.15E+06 - - - -1.9661 - 1.989 0.325 - 114.7 1 2 1 -0.0023 9 0 0 0 4.59E+07 4.27E+07 - - - 4.2352 0.9868 221125_WJC_METTL3_EV_vs_WT_F05.07295.07295.2 0.0253 16-Aug K.LVEQLKEER.E "sp|O95232|LC7L3_HUMAN,tr|J3KPP4|J3KPP4_HUMAN" 2 1142.6295 0.93 60389 7295 2 1142.627706 572.322 Luc7-like protein 3 OS=Homo sapiens OX=9606 GN=LUC7L3 PE=1 SV=2 4.79 1788.5 - 429172 - - - -1.6033 - 1.538 0.322 - 289.6 1 2 1 -0.0018 9 0 0 0 7.66E+06 8.28E+06 - - - 2.6641 0.9868 221125_WJC_METTL3_EV_vs_WT_F05.07298.07298.2 0.155 14-Aug K.EQNVPVPK[136.11].E "sp|Q6P2I3|FAH2B_HUMAN,sp|Q96GK7|FAH2A_HUMAN" 2 917.5062 5.11 60390 7298 2 917.505271 459.7604 Fumarylacetoacetate hydrolase domain-containing protein 2B OS=Homo sapiens OX=9606 GN=FAHD2B PE=1 SV=1 6.1 1788.9 - 848964 - - - -0.9929 - 1.259 0.11 - 224.9 1 2 0 -0.0009 8 0 0 0 1.90E+08 3.73E+07 - - - 0.5478 0.9997 221125_WJC_METTL3_EV_vs_WT_F05.07299.07299.2 0.00537 18-Oct R.GLQEGYENSR[166.11].C "sp|Q9C0C9|UBE2O_HUMAN,tr|K7ES11|K7ES11_HUMAN" 2 1161.529 0.85 60391 7299 2 1161.528298 581.7718 (E3-independent) E2 ubiquitin-conjugating enzyme OS=Homo sapiens OX=9606 GN=UBE2O PE=1 SV=3 4.53 1789 - 655765 - - - -0.5923 - 1.947 0.362 - 386 1 2 0 -0.0007 10 0 0 0 1.00E+07 1.17E+07 - - - 3.5743 0.9988 221125_WJC_METTL3_EV_vs_WT_F05.07300.07300.2 0.0106 14-Jul K.DTYIENEK.L "sp|P04843|RPN1_HUMAN,tr|B7Z4L4|B7Z4L4_HUMAN" 2 1010.4557 1.46 60392 7300 2 1010.457452 506.2351 Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit 1 OS=Homo sapiens OX=9606 GN=RPN1 PE=1 SV=1 4.14 1789 - 4.42E+06 - - - 1.7774 - 1.302 0.411 - 198.9 1 2 0 0.0018 8 0 0 0 1.09E+08 7.43E+07 - - - 2.872 0.9887 221125_WJC_METTL3_EV_vs_WT_F05.07302.07302.2 5.83E-06 22-Nov E.VATNSELVQSGK.S "sp|Q04695|K1C17_HUMAN,sp|P02533|K1C14_HUMAN,tr|K7ESE1|K7ESE1_HUMAN,tr|F5GWP8|F5GWP8_HUMAN" 4 1231.6408 999 60394 7302 2 1231.638977 616.8277 "Keratin, type I cytoskeletal 17 OS=Homo sapiens OX=9606 GN=KRT17 PE=1 SV=2" 5.97 1789.2 - 468037 - - - -1.5053 - 2.442 0.468 - 579.9 1 1 0 -0.0019 12 0 0 0 9.19E+06 0.00E+00 - - - 4.8462 0.9999 221125_WJC_METTL3_EV_vs_WT_F05.07303.07303.2 4.66E-05 16-Sep R.SYSTTYEER.N "sp|Q15758|AAAT_HUMAN,tr|M0QXM4|M0QXM4_HUMAN,tr|M0QX44|M0QX44_HUMAN" 3 1134.4829 0.8 60395 7303 2 1134.482313 568.2487 Neutral amino acid transporter B(0) OS=Homo sapiens OX=9606 GN=SLC1A5 PE=1 SV=2 4.53 1789.4 - 351306 - - - -0.5465 - 1.617 0.58 - 247.9 1 2 0 -0.0006 9 0 0 0 8.85E+06 1.11E+07 - - - 4.715 0.9993 221125_WJC_METTL3_EV_vs_WT_F05.07304.07304.2 6.72E-05 18-Sep R.QDVDNASLAR[166.11].L "sp|P08670|VIME_HUMAN,tr|B0YJC5|B0YJC5_HUMAN,tr|B0YJC4|B0YJC4_HUMAN" 3 1097.5341 1.57 60396 7304 2 1097.531825 549.7743 Vimentin OS=Homo sapiens OX=9606 GN=VIM PE=1 SV=4 4.21 1789.5 - 317450 - - - -2.0464 - 1.555 0.449 - 256.6 1 2 0 -0.0022 10 0 0 0 1.08E+07 6.92E+06 - - - 3.5889 0.9995 221125_WJC_METTL3_EV_vs_WT_F05.07307.07307.2 0.00697 14-Aug K.DTYIENEK[136.11].L "sp|P04843|RPN1_HUMAN,tr|B7Z4L4|B7Z4L4_HUMAN" 2 1018.4699 1.43 60397 7307 2 1018.470013 510.2422 Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit 1 OS=Homo sapiens OX=9606 GN=RPN1 PE=1 SV=1 4.14 1789.9 - 4.45E+06 - - - 0.1542 - 1.416 0.386 - 247.4 1 2 0 0.0002 8 0 0 0 1.07E+08 7.43E+07 - - - 2.941 0.9903 221125_WJC_METTL3_EV_vs_WT_F05.07308.07308.3 0.0074 Dec-32 K.LVEQLKEER.E "sp|O95232|LC7L3_HUMAN,tr|J3KPP4|J3KPP4_HUMAN" 2 1142.6295 1.07 60398 7308 3 1142.629451 381.8838 Luc7-like protein 3 OS=Homo sapiens OX=9606 GN=LUC7L3 PE=1 SV=2 4.79 1789.9 - 2.83E+06 - - - -0.0761 - 2.217 0.166 - 177.3 1 2 1 -0.0001 9 0 0 0 4.56E+07 4.27E+07 - - - 2.7902 0.9997 221125_WJC_METTL3_EV_vs_WT_F05.07309.07309.3 0.000845 Dec-40 R.LLEVQGSR[166.11]PGK[136.11].N "sp|P62136|PP1A_HUMAN,tr|E9PMD7|E9PMD7_HUMAN" 2 1200.6945 1.07 60399 7309 3 1200.694313 401.2388 Serine\threonine-protein phosphatase PP1-alpha catalytic subunit OS=Homo sapiens OX=9606 GN=PPP1CA PE=1 SV=1 8.75 1790 - 2.42E+06 - - - -0.1899 - 1.966 0.333 - 141 1 2 0 -0.0002 11 0 0 0 7.62E+07 7.15E+07 - - - 4.173 0.9997 221125_WJC_METTL3_EV_vs_WT_F05.07311.07311.2 0.00466 18-Sep K.VSGGPSLEQR[166.11].F "sp|Q9Y262|EIF3L_HUMAN,tr|B0QY89|B0QY89_HUMAN,tr|C9K0Q7|C9K0Q7_HUMAN,tr|C9JHP4|C9JHP4_HUMAN,tr|B0QY90|B0QY90_HUMAN" 5 1038.5333 5.58 60401 7311 2 1038.533444 520.2739 Eukaryotic translation initiation factor 3 subunit L OS=Homo sapiens OX=9606 GN=EIF3L PE=1 SV=1 5.97 1790.1 - 1.30E+06 - - - 0.0973 - 1.974 0.379 - 255.3 1 2 0 0.0001 10 0 0 0 2.24E+08 4.02E+07 - - - 3.7385 0.9891 221125_WJC_METTL3_EV_vs_WT_F05.07313.07313.2 0.429 12-Jul K.EQSIVEK[136.11].F "sp|Q86U44|MTA70_HUMAN,tr|H0YFV6|H0YFV6_HUMAN" 2 839.448 0.03 60403 7313 2 839.448271 420.7313 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 4.53 1790.3 - 913728 - - - 0.3252 - 1.436 0.054 - 243.2 1 2 0 0.0003 7 0 0 0 2.04E+06 6.93E+07 - - - 0.5863 0.9897 221125_WJC_METTL3_EV_vs_WT_F05.07314.07314.2 0.246 16-Jul R.SEPSAGIPK[136.11].V "sp|Q9Y520|PRC2C_HUMAN,tr|E7EPN9|E7EPN9_HUMAN" 2 892.4745 0.91 60404 7314 2 892.474759 447.2445 Protein PRRC2C OS=Homo sapiens OX=9606 GN=PRRC2C PE=1 SV=4 5.72 1790.4 - 770674 - - - 0.2375 - 1.446 0.087 - 189.4 2 2 0 0.0002 9 0 0 0 6.06E+07 6.69E+07 - - - 0.616 0.9998 221125_WJC_METTL3_EV_vs_WT_F05.07315.07315.2 0.000119 22-Dec K.VGPATPSAQVGK[136.11].W "sp|Q13428|TCOF_HUMAN,tr|E7ETY2|E7ETY2_HUMAN,tr|H0Y8Y7|H0Y8Y7_HUMAN,tr|A0A3B3IS06|A0A3B3IS06_HUMAN,tr|A0A6I8PRA0|A0A6I8PRA0_HUMAN" 5 1118.6175 6.11 60405 7315 2 1118.617321 560.316 Treacle protein OS=Homo sapiens OX=9606 GN=TCOF1 PE=1 SV=3 8.72 1790.5 - 686770 - - - -0.1806 - 1.965 0.418 - 427.4 1 2 0 -0.0002 12 0 0 0 1.78E+08 2.91E+07 - - - 3.9056 0.9751 221125_WJC_METTL3_EV_vs_WT_F05.07316.07316.2 0.00174 14-Jun T.AAYGHFGR.D sp|P31153|METK2_HUMAN 1 877.4195 1.87 60406 7316 2 877.419804 439.717 S-adenosylmethionine synthase isoform type-2 OS=Homo sapiens OX=9606 GN=MAT2A PE=1 SV=1 8.8 1790.7 - 610751 - - - 0.3636 - 1.379 0.438 - 114.5 1 1 0 0.0003 8 0 0 0 1.59E+07 8.50E+06 - - - 3.2452 0.9995 221125_WJC_METTL3_EV_vs_WT_F05.07317.07317.2 0.0592 20-Aug R.LLEVQGSRPGK.N "sp|P62136|PP1A_HUMAN,tr|E9PMD7|E9PMD7_HUMAN" 2 1182.6721 1.63 60407 7317 2 1182.672716 592.3433 Serine\threonine-protein phosphatase PP1-alpha catalytic subunit OS=Homo sapiens OX=9606 GN=PPP1CA PE=1 SV=1 8.75 1790.8 - 244871 - - - 0.5454 - 1.691 0.35 - 215.3 1 2 0 0.0006 11 0 0 0 9.64E+06 5.90E+06 - - - 3.047 0.9988 221125_WJC_METTL3_EV_vs_WT_F05.07320.07320.2 0.026 14-Jul K.NETSAPFK.E "sp|P07814|SYEP_HUMAN,tr|V9GYZ6|V9GYZ6_HUMAN" 2 892.429 0.43 60408 7320 2 892.429693 447.2218 Bifunctional glutamate\proline--tRNA ligase OS=Homo sapiens OX=9606 GN=EPRS1 PE=1 SV=5 6 1791.2 - 734215 - - - 0.7239 - 1.339 0.327 - 249.9 1 2 0 0.0006 8 0 0 0 1.60E+07 3.75E+07 - - - 2.3364 0.9996 221125_WJC_METTL3_EV_vs_WT_F05.07321.07321.2 2.43E-05 16-Sep K.MTVNNLHPR[166.11].V "sp|Q9BY77|PDIP3_HUMAN,tr|F6VRR5|F6VRR5_HUMAN" 2 1090.5581 1.7 60409 7321 2 1090.555928 546.2863 Polymerase delta-interacting protein 3 OS=Homo sapiens OX=9606 GN=POLDIP3 PE=1 SV=2 9.52 1791.3 - 742932 - - - -2.0081 - 1.964 0.422 - 476.2 1 2 0 -0.0022 9 0 0 0 1.06E+08 6.23E+07 - - - 4.11 0.9351 221125_WJC_METTL3_EV_vs_WT_F05.07324.07324.2 0.0115 14-Nov M.TVNNLHPR[166.11].V "sp|Q9BY77|PDIP3_HUMAN,tr|F6VRR5|F6VRR5_HUMAN" 2 959.5176 1.82 60412 7324 2 959.518294 480.7661 Polymerase delta-interacting protein 3 OS=Homo sapiens OX=9606 GN=POLDIP3 PE=1 SV=2 9.44 1791.6 - 609273 - - - 0.6889 - 1.897 0.19 - 466.6 1 1 0 0.0007 8 0 0 0 7.83E+07 4.31E+07 - - - 2.3752 0.9759 221125_WJC_METTL3_EV_vs_WT_F05.07330.07330.2 0.443 22-May R.ELTNQQEASVER[166.11].Q "sp|Q14203|DCTN1_HUMAN,tr|A0A804CDA6|A0A804CDA6_HUMAN,tr|E7EX90|E7EX90_HUMAN,tr|A0A7P0Z4C3|A0A7P0Z4C3_HUMAN,tr|Q6AWB1|Q6AWB1_HUMAN" 5 1412.6771 2.16 60417 7330 2 1412.680356 707.3458 Dynactin subunit 1 OS=Homo sapiens OX=9606 GN=DCTN1 PE=1 SV=3 4.25 1792.3 - 47680.9 - - - 2.3006 - 0.967 0.239 - 59.9 1 2 0 0.0032 12 0 0 0 1.40E+07 6.49E+06 - - - 0.7169 0.9996 221125_WJC_METTL3_EV_vs_WT_F05.07333.07333.2 0.00474 18-Oct R.GGGGGFGYQK[136.11].T sp|Q9NVP1|DDX18_HUMAN 1 934.4388 1.05 60419 7333 2 934.440049 468.2267 ATP-dependent RNA helicase DDX18 OS=Homo sapiens OX=9606 GN=DDX18 PE=1 SV=2 8.59 1792.6 - 990469 - - - 1.3045 - 2.053 0.38 - 373 1 2 0 0.0012 10 0 0 0 1.56E+07 1.48E+07 - - - 3.8551 0.995 221125_WJC_METTL3_EV_vs_WT_F05.07334.07334.2 0.165 16-Nov R.LRAEIDNVK.K "sp|P13647|K2C5_HUMAN,tr|H0YI76|H0YI76_HUMAN" 2 1056.5928 1105.76 60420 7334 2 1056.593164 529.3037 "Keratin, type II cytoskeletal 5 OS=Homo sapiens OX=9606 GN=KRT5 PE=1 SV=3" 6.07 1792.7 - 2.32E+06 - - - 0.3843 - 1.948 0.3 - 455.1 1 2 1 0.0004 9 0 0 0 9.22E+07 8.34E+04 - - - 3.1858 0.998 221125_WJC_METTL3_EV_vs_WT_F05.07336.07336.2 0.00924 14-Aug K.SPFEQHIK[136.11].N sp|Q92520|FAM3C_HUMAN 1 992.5171 1.27 60422 7336 2 992.51777 497.2658 Protein FAM3C OS=Homo sapiens OX=9606 GN=FAM3C PE=1 SV=1 6.47 1792.8 - 1.08E+06 - - - 0.6942 - 1.479 0.23 - 268.1 1 2 0 0.0007 8 0 0 0 2.36E+07 1.85E+07 - - - 1.9199 0.9985 221125_WJC_METTL3_EV_vs_WT_F05.07337.07337.2 0.0122 14-May K.DGTGWASK.Q "sp|P48634|PRC2A_HUMAN,sp|Q9Y520|PRC2C_HUMAN,tr|E7EPN9|E7EPN9_HUMAN" 3 820.3715 0.96 60423 7337 2 820.372197 411.193 Protein PRRC2A OS=Homo sapiens OX=9606 GN=PRRC2A PE=1 SV=3 5.84 1792.9 - 756721 - - - 0.8106 - 1.225 0.344 - 98.2 1 2 0 0.0007 8 0 0 0 2.41E+07 2.51E+07 - - - 2.1936 0.9995 221125_WJC_METTL3_EV_vs_WT_F05.07338.07338.2 0.0215 16-Oct R.SYSTTYEER[166.11].N "sp|Q15758|AAAT_HUMAN,tr|M0QXM4|M0QXM4_HUMAN,tr|M0QX44|M0QX44_HUMAN" 3 1144.4912 0.76 60424 7338 2 1144.488279 573.2529 Neutral amino acid transporter B(0) OS=Homo sapiens OX=9606 GN=SLC1A5 PE=1 SV=2 4.53 1793 - 562739 - - - -2.5548 - 1.782 0.504 - 306.4 1 2 0 -0.0029 9 0 0 0 8.85E+06 1.16E+07 - - - 4.434 0.926 221125_WJC_METTL3_EV_vs_WT_F05.07339.07339.2 1.08 18-May R.AISAPTSPTR.L "sp|Q9NQG6|MID51_HUMAN,tr|B0QY95|B0QY95_HUMAN" 2 999.5349 1.31 60425 7339 2 999.537461 500.7747 Mitochondrial dynamics protein MID51 OS=Homo sapiens OX=9606 GN=MIEF1 PE=1 SV=1 9.79 1793.1 - 372364 - - - 2.5532 - 1.224 0.131 - 81.6 14 2 0 0.0026 10 0 0 0 8.49E+06 6.46E+06 - - - 0.06 0.9997 221125_WJC_METTL3_EV_vs_WT_F05.07340.07340.2 0.00105 20-Aug K.LSPSPTTEDPR.V "sp|Q9BTC8|MTA3_HUMAN,tr|E7EQY4|E7EQY4_HUMAN,tr|E7EV10|E7EV10_HUMAN,tr|F6RRE2|F6RRE2_HUMAN" 4 1198.583 0.33 60426 7340 2 1198.583245 600.2988 Metastasis-associated protein MTA3 OS=Homo sapiens OX=9606 GN=MTA3 PE=1 SV=2 4.37 1793.3 - 331826 - - - 0.2203 - 1.647 0.454 - 145.2 1 2 0 0.0003 11 0 0 0 6.73E+06 2.06E+07 - - - 3.744 0.9994 221125_WJC_METTL3_EV_vs_WT_F05.07343.07343.2 0.000852 20-Aug K.EFTNQEAAEPK.E sp|Q32MZ4|LRRF1_HUMAN 1 1262.5779 0.76 60429 7343 2 1262.576508 632.2962 Leucine-rich repeat flightless-interacting protein 1 OS=Homo sapiens OX=9606 GN=LRRFIP1 PE=1 SV=2 4.25 1793.6 - 145097 - - - -1.0993 - 1.656 0.37 - 105.3 1 2 0 -0.0014 11 0 0 0 3.40E+06 4.45E+06 - - - 3.1379 0.838 221125_WJC_METTL3_EV_vs_WT_F05.07345.07345.2 5.56 18-Mar K.K[136.11]PYAC[160.03]DEC[160.03]AK[136.11].A sp|Q96N95|ZN396_HUMAN 1 1256.55 0.001 60431 7345 2 1256.549918 629.2823 Zinc finger protein 396 OS=Homo sapiens OX=9606 GN=ZNF396 PE=1 SV=2 6.05 1793.9 - 64437.1 - - - -0.1003 - 0.777 0.075 - 24.9 2 2 0 -0.0001 10 0 0 0 0.00E+00 1.34E+07 - - - -1.2438 1 221125_WJC_METTL3_EV_vs_WT_F05.07348.07348.3 0.00616 17/48 K.VLATVTK[136.11]PVGGDK[136.11].N "sp|Q02878|RL6_HUMAN,tr|F8VZ45|F8VZ45_HUMAN,tr|F8VWR1|F8VWR1_HUMAN,tr|F8VU16|F8VU16_HUMAN,tr|U3KQR5|U3KQR5_HUMAN,tr|F8VZA3|F8VZA3_HUMAN" 6 1299.7733 1.01 60432 7348 3 1299.773609 434.265 60S ribosomal protein L6 OS=Homo sapiens OX=9606 GN=RPL6 PE=1 SV=3 8.56 1794.3 - 3.36E+06 - - - 0.2362 - 2.886 0.442 - 403.7 1 2 0 0.0003 13 0 0 0 1.41E+08 1.40E+08 - - - 6.3414 0.9693 221125_WJC_METTL3_EV_vs_WT_F05.07350.07350.2 0.0469 14-Sep M.TVNNLHPR.V "sp|Q9BY77|PDIP3_HUMAN,tr|F6VRR5|F6VRR5_HUMAN" 2 949.5094 1.84 60434 7350 2 949.509621 475.762 Polymerase delta-interacting protein 3 OS=Homo sapiens OX=9606 GN=POLDIP3 PE=1 SV=2 9.44 1794.4 - 3.22E+06 - - - 0.2717 - 1.609 0.342 - 263.4 1 1 0 0.0003 8 0 0 0 7.84E+07 4.25E+07 - - - 3.0014 0.9998 221125_WJC_METTL3_EV_vs_WT_F05.07351.07351.2 0.000914 22-Dec R.VLANPGNSQVAR.V "sp|Q14974|IMB1_HUMAN,tr|J3QR48|J3QR48_HUMAN" 2 1224.6575 1.5 60435 7351 2 1224.659597 613.336 Importin subunit beta-1 OS=Homo sapiens OX=9606 GN=KPNB1 PE=1 SV=2 9.72 1794.5 - 2.50E+06 - - - 1.7254 - 2.435 0.486 - 503.5 1 2 0 0.0021 12 0 0 0 1.06E+08 7.02E+07 - - - 4.9715 0.9999 221125_WJC_METTL3_EV_vs_WT_F05.07352.07352.3 1.04E-06 16/48 K.VLATVTKPVGGDK.N "sp|Q02878|RL6_HUMAN,tr|F8VZ45|F8VZ45_HUMAN,tr|F8VWR1|F8VWR1_HUMAN,tr|F8VU16|F8VU16_HUMAN,tr|U3KQR5|U3KQR5_HUMAN,tr|F8VZA3|F8VZA3_HUMAN" 6 1283.7449 1.01 60436 7352 3 1283.746049 428.9222 60S ribosomal protein L6 OS=Homo sapiens OX=9606 GN=RPL6 PE=1 SV=3 8.56 1794.5 - 2.07E+06 - - - 0.8935 - 2.33 0.413 - 383.3 1 2 0 0.0011 13 0 0 0 1.41E+08 1.40E+08 - - - 5.4376 0.9853 221125_WJC_METTL3_EV_vs_WT_F05.07353.07353.2 0.00274 12-Aug T.VNNLHPR.V "sp|Q9BY77|PDIP3_HUMAN,tr|F6VRR5|F6VRR5_HUMAN" 2 848.4617 1.77 60437 7353 2 848.462041 425.2381 Polymerase delta-interacting protein 3 OS=Homo sapiens OX=9606 GN=POLDIP3 PE=1 SV=2 9.73 1794.6 - 1.29E+06 - - - 0.4208 - 2.059 0.346 - 305.9 1 1 0 0.0004 7 0 0 0 2.86E+07 1.61E+07 - - - 3.8848 0.9999 221125_WJC_METTL3_EV_vs_WT_F05.07357.07357.2 0.000323 22-Sep K.LSSNLGGPGSSR[166.11].T sp|P48634|PRC2A_HUMAN 1 1140.5763 1.69 60441 7357 2 1140.575657 571.2954 Protein PRRC2A OS=Homo sapiens OX=9606 GN=PRRC2A PE=1 SV=3 9.75 1795.1 - 489373 - - - -0.5374 - 2.473 0.438 - 233.4 1 2 0 -0.0006 12 0 0 0 7.31E+07 4.34E+07 - - - 4.6582 0.9999 221125_WJC_METTL3_EV_vs_WT_F05.07359.07359.2 3.95E-06 14/24 K.VLATVTK[136.11]PVGGDK[136.11].N "sp|Q02878|RL6_HUMAN,tr|F8VZ45|F8VZ45_HUMAN,tr|F8VWR1|F8VWR1_HUMAN,tr|F8VU16|F8VU16_HUMAN,tr|U3KQR5|U3KQR5_HUMAN,tr|F8VZA3|F8VZA3_HUMAN" 6 1299.7733 1.01 60443 7359 2 1299.773834 650.8939 60S ribosomal protein L6 OS=Homo sapiens OX=9606 GN=RPL6 PE=1 SV=3 8.56 1795.4 - 332434 - - - 0.4093 - 2.665 0.467 - 700.3 1 2 0 0.0005 13 0 0 0 1.68E+07 1.66E+07 - - - 5.0058 0.9986 221125_WJC_METTL3_EV_vs_WT_F05.07366.07366.2 0.0281 13/22 K.LSSNLGGPGSSR.T sp|P48634|PRC2A_HUMAN 1 1130.568 1.71 60448 7366 2 1130.571779 566.2913 Protein PRRC2A OS=Homo sapiens OX=9606 GN=PRRC2A PE=1 SV=3 9.75 1796.3 - 1.20E+06 - - - 3.3426 - 2.45 0.334 - 416.9 1 2 0 0.0038 12 0 0 0 7.43E+07 4.34E+07 - - - 3.8645 0.9742 221125_WJC_METTL3_EV_vs_WT_F05.07367.07367.2 0.00112 16-Jul E.SAALHAGLR.K "sp|O75410|TACC1_HUMAN,tr|E7EVI4|E7EVI4_HUMAN,tr|B4E3H6|B4E3H6_HUMAN,tr|H0YAY0|H0YAY0_HUMAN,tr|H0YBT8|H0YBT8_HUMAN,tr|E7ET87|E7ET87_HUMAN" 6 894.5035 0.58 60449 7367 2 894.50428 448.2591 Transforming acidic coiled-coil-containing protein 1 OS=Homo sapiens OX=9606 GN=TACC1 PE=1 SV=2 9.49 1796.4 - 673442 - - - 0.8172 - 1.707 0.376 - 234.5 1 1 0 0.0007 9 0 0 0 1.15E+07 1.99E+07 - - - 3.3649 0.8776 221125_WJC_METTL3_EV_vs_WT_F05.07368.07368.3 0.0569 Aug-32 R.AR[166.11]YEDPTLR[166.11].N "sp|Q6W2J9|BCOR_HUMAN,tr|H7BZ37|H7BZ37_HUMAN,tr|A1A564|A1A564_HUMAN,tr|H7C2V9|H7C2V9_HUMAN,tr|H7BYY2|H7BYY2_HUMAN,tr|H7C231|H7C231_HUMAN" 6 1139.5838 0.001 60450 7368 3 1139.588748 380.8685 BCL-6 corepressor OS=Homo sapiens OX=9606 GN=BCOR PE=1 SV=1 6.11 1796.5 - 576083 - - - 4.3314 - 1.853 0.195 - 134.2 1 2 1 0.0049 9 0 0 0 0.00E+00 6.82E+06 - - - 2.5716 0.9999 221125_WJC_METTL3_EV_vs_WT_F05.07369.07369.2 0.129 13/20 R.MGAGLGHGMDR.V "sp|P52272|HNRPM_HUMAN,tr|A0A087X0X3|A0A087X0X3_HUMAN,tr|M0QZM1|M0QZM1_HUMAN,tr|M0R2T0|M0R2T0_HUMAN" 4 1100.4855 1.59 60451 7369 2 1100.485573 551.25 Heterogeneous nuclear ribonucleoprotein M OS=Homo sapiens OX=9606 GN=HNRNPM PE=1 SV=3 6.5 1796.6 - 543083 - - - 0.0363 - 2.347 0.438 - 787.3 1 2 0 0 11 0 0 0 1.75E+07 1.11E+07 - - - 4.584 0.9998 221125_WJC_METTL3_EV_vs_WT_F05.07370.07370.2 0.000174 20-Dec R.MGAGLGHGMDR[166.11].V "sp|P52272|HNRPM_HUMAN,tr|A0A087X0X3|A0A087X0X3_HUMAN,tr|M0QZM1|M0QZM1_HUMAN,tr|M0R2T0|M0R2T0_HUMAN" 4 1110.4938 1.63 60452 7370 2 1110.495503 556.2542 Heterogeneous nuclear ribonucleoprotein M OS=Homo sapiens OX=9606 GN=HNRNPM PE=1 SV=3 6.5 1796.7 - 383484 - - - 1.5309 - 2.389 0.518 - 616 1 2 0 0.0017 11 0 0 0 1.74E+07 1.07E+07 - - - 5.2223 0.9965 221125_WJC_METTL3_EV_vs_WT_F05.07375.07375.2 0.857 14-Aug K.SEISELRR.T "sp|Q04695|K1C17_HUMAN,sp|P02533|K1C14_HUMAN,tr|F5GWP8|F5GWP8_HUMAN" 3 988.5302 228.43 60456 7375 2 988.530427 495.2724 "Keratin, type I cytoskeletal 17 OS=Homo sapiens OX=9606 GN=KRT17 PE=1 SV=2" 5.86 1797.4 - 5.86E+06 - - - 0.2721 - 1.555 0.136 - 169.4 1 2 0 0.0003 8 0 0 0 1.73E+09 7.57E+06 - - - 1.3769 0.9927 221125_WJC_METTL3_EV_vs_WT_F05.07376.07376.2 0.288 14-Jul K.EQNVPVPK.E "sp|Q6P2I3|FAH2B_HUMAN,sp|Q96GK7|FAH2A_HUMAN" 2 909.492 1.07 60457 7376 2 909.491727 455.7533 Fumarylacetoacetate hydrolase domain-containing protein 2B OS=Homo sapiens OX=9606 GN=FAHD2B PE=1 SV=1 6.1 1797.4 - 1.34E+06 - - - -0.2804 - 1.009 0.239 - 170.1 1 2 0 -0.0003 8 0 0 0 1.36E+07 1.27E+07 - - - 0.8332 0.9993 221125_WJC_METTL3_EV_vs_WT_F05.07377.07377.2 0.000614 16-Sep K.NAGFTPQER[166.11].Q "sp|P27695|APEX1_HUMAN,tr|G3V3M6|G3V3M6_HUMAN,tr|G3V5Q1|G3V5Q1_HUMAN" 3 1028.4915 0.19 60458 7377 2 1028.489058 515.253 DNA-(apurinic or apyrimidinic site) endonuclease OS=Homo sapiens OX=9606 GN=APEX1 PE=1 SV=2 6 1797.5 - 972528 - - - -2.353 - 1.977 0.377 - 366.4 1 2 0 -0.0024 9 0 0 0 1.07E+07 5.67E+07 - - - 3.7966 0.9266 221125_WJC_METTL3_EV_vs_WT_F05.07380.07380.2 4.66 22-Jun R.AGALQPPASGTR.V sp|Q14774|HLX_HUMAN 1 1124.5938 1.45 60461 7380 2 1124.595157 563.3042 H2.0-like homeobox protein OS=Homo sapiens OX=9606 GN=HLX PE=1 SV=3 9.79 1797.9 - 351025 - - - 1.188 - 1.265 0.031 - 117.3 6 2 0 0.0013 12 0 0 0 2.98E+07 2.05E+07 - - - -0.4595 0.9997 221125_WJC_METTL3_EV_vs_WT_F05.07386.07386.2 0.000365 16-Oct R.VTDALNATR[166.11].A "sp|P10809|CH60_HUMAN,tr|A0A7I2V2X6|A0A7I2V2X6_HUMAN,tr|A0A7I2YQK6|A0A7I2YQK6_HUMAN,tr|A0A7I2V599|A0A7I2V599_HUMAN" 4 969.5119 1.32 60465 7386 2 969.510993 485.7632 "60 kDa heat shock protein, mitochondrial OS=Homo sapiens OX=9606 GN=HSPD1 PE=1 SV=2" 5.81 1798.5 - 1.46E+06 - - - -0.9139 - 1.927 0.364 - 383.1 1 2 0 -0.0009 9 0 0 0 2.98E+08 2.25E+08 - - - 3.627 0.9705 221125_WJC_METTL3_EV_vs_WT_F05.07395.07395.2 34.2 16-Jul K.EGIPPDQQR[166.11].L "sp|P62979|RS27A_HUMAN,sp|P0CG48|UBC_HUMAN,sp|P0CG48|UBC_HUMAN,sp|P0CG48|UBC_HUMAN,sp|P0CG48|UBC_HUMAN,sp|P0CG48|UBC_HUMAN,sp|P0CG48|UBC_HUMAN,sp|P0CG48|UBC_HUMAN,sp|P0CG48|UBC_HUMAN,sp|P0CG48|UBC_HUMAN,sp|P0CG47|UBB_HUMAN,sp|P0CG47|UBB_HUMAN,sp|P0CG47|UBB_HUMAN,sp|P62987|RL40_HUMAN,tr|F5H388|F5H388_HUMAN,tr|F5H388|F5H388_HUMAN,tr|F5GYU3|F5GYU3_HUMAN,tr|F5GYU3|F5GYU3_HUMAN,tr|B4DV12|B4DV12_HUMAN,tr|B4DV12|B4DV12_HUMAN,tr|J3QSA3|J3QSA3_HUMAN,tr|Q5PY61|Q5PY61_HUMAN,tr|Q5PY61|Q5PY61_HUMAN,tr|Q5PY61|Q5PY61_HUMAN,tr|F5H2Z3|F5H2Z3_HUMAN,tr|F5H2Z3|F5H2Z3_HUMAN,tr|M0R2S1|M0R2S1_HUMAN,tr|J3QS39|J3QS39_HUMAN,tr|J3QTR3|J3QTR3_HUMAN,tr|Q96C32|Q96C32_HUMAN,tr|Q96C32|Q96C32_HUMAN,tr|Q96C32|Q96C32_HUMAN,tr|Q96C32|Q96C32_HUMAN,tr|M0R1V7|M0R1V7_HUMAN,tr|F5H747|F5H747_HUMAN,tr|F5H747|F5H747_HUMAN,tr|F5GXK7|F5GXK7_HUMAN,tr|F5GXK7|F5GXK7_HUMAN,tr|M0R1M6|M0R1M6_HUMAN,tr|F5H6Q2|F5H6Q2_HUMAN,tr|F5H6Q2|F5H6Q2_HUMAN,tr|F5GZ39|F5GZ39_HUMAN,tr|J3QKN0|J3QKN0_HUMAN,tr|J3QKN0|J3QKN0_HUMAN,tr|J3QKN0|J3QKN0_HUMAN,tr|F5H265|F5H265_HUMAN,tr|F5H265|F5H265_HUMAN,tr|A0A2R8Y422|A0A2R8Y422_HUMAN" 48 1048.5177 0.72 60472 7395 2 1048.517924 525.2661 Ubiquitin-40S ribosomal protein S27a OS=Homo sapiens OX=9606 GN=RPS27A PE=1 SV=2 4.37 1799.6 - 1.04E+06 - - - 0.2203 - 1.196 0.049 - 152.4 1 2 0 0.0002 9 0 0 0 3.75E+07 5.19E+07 - - - -0.0794 0.9012 221125_WJC_METTL3_EV_vs_WT_F05.07396.07396.2 0.00683 18-Oct M.GAGLGHGMDR[166.11].V "sp|P52272|HNRPM_HUMAN,tr|A0A087X0X3|A0A087X0X3_HUMAN,tr|M0QZM1|M0QZM1_HUMAN,tr|M0R2T0|M0R2T0_HUMAN" 4 979.4533 1.15 60473 7396 2 979.453355 490.7339 Heterogeneous nuclear ribonucleoprotein M OS=Homo sapiens OX=9606 GN=HNRNPM PE=1 SV=3 6.74 1799.7 - 926646 - - - 0.0378 - 1.732 0.175 - 262.7 1 1 0 0 10 0 0 0 1.31E+07 1.14E+07 - - - 1.8667 0.998 221125_WJC_METTL3_EV_vs_WT_F05.07398.07398.2 0.331 14-Jul R.ISIC[160.03]SSDK.R sp|Q13547|HDAC1_HUMAN 1 908.4273 1.64 60475 7398 2 908.426595 455.2209 Histone deacetylase 1 OS=Homo sapiens OX=9606 GN=HDAC1 PE=1 SV=1 5.83 1799.9 - 963427 - - - -0.8124 - 1.452 0.232 - 136.9 1 2 0 -0.0007 8 0 0 0 2.14E+07 1.31E+07 - - - 1.8791 0.9997 221125_WJC_METTL3_EV_vs_WT_F05.07399.07399.3 0.169 Dec-40 R.AVEPGRPPLSR.R "sp|Q5TA31|RN187_HUMAN,tr|A0A1X7SBW3|A0A1X7SBW3_HUMAN" 2 1177.6568 0.89 60476 7399 3 1177.655839 393.5595 E3 ubiquitin-protein ligase RNF187 OS=Homo sapiens OX=9606 GN=RNF187 PE=1 SV=2 9.64 1800 - 701550 - - - -0.7778 - 1.807 0.356 - 197.1 1 2 0 -0.0009 11 0 0 0 2.42E+07 2.72E+07 - - - 4.1896 0.9909 221125_WJC_METTL3_EV_vs_WT_F05.07403.07403.2 0.0394 16-Aug K.LIEVDDERK.L "sp|P62753|RS6_HUMAN,tr|A2A3R7|A2A3R7_HUMAN" 2 1115.5823 0.36 60480 7403 2 1115.584696 558.7984 40S ribosomal protein S6 OS=Homo sapiens OX=9606 GN=RPS6 PE=1 SV=1 4.32 1800.5 - 236958 - - - 2.1899 - 1.803 0.084 - 184.4 1 2 0 0.0024 9 0 0 0 2.30E+06 6.42E+06 - - - 1.366 0.9998 221125_WJC_METTL3_EV_vs_WT_F05.07409.07409.2 5.23E-05 20-Oct K.TPGPGAQSALR.A "sp|P62263|RS14_HUMAN,tr|A0A2R8Y811|A0A2R8Y811_HUMAN,tr|E5RH77|E5RH77_HUMAN" 3 1053.5567 1.52 60484 7409 2 1053.55607 527.7856 40S ribosomal protein S14 OS=Homo sapiens OX=9606 GN=RPS14 PE=1 SV=3 9.41 1801.2 - 4.85E+06 - - - -0.6046 - 2.056 0.394 - 381 1 2 0 -0.0006 11 0 0 0 4.91E+08 3.22E+08 - - - 3.9007 0.9984 221125_WJC_METTL3_EV_vs_WT_F05.07410.07410.2 0.559 14-Aug R.ISIC[160.03]SSDK[136.11].R sp|Q13547|HDAC1_HUMAN 1 916.4415 1.62 60485 7410 2 916.44002 459.228 Histone deacetylase 1 OS=Homo sapiens OX=9606 GN=HDAC1 PE=1 SV=1 5.83 1801.3 - 794808 - - - -1.651 - 1.4 0.323 - 166 1 2 0 -0.0015 8 0 0 0 2.05E+07 1.26E+07 - - - 2.441 0.9279 221125_WJC_METTL3_EV_vs_WT_F05.07412.07412.3 0.558 Aug-36 R.AMQHAEVYYK[136.11].L "sp|Q9BVG4|PBDC1_HUMAN,tr|A6NDF3|A6NDF3_HUMAN" 2 1246.5896 0.32 60487 7412 3 1246.589771 416.5371 Protein PBDC1 OS=Homo sapiens OX=9606 GN=PBDC1 PE=1 SV=1 6.79 1801.6 - 415586 - - - 0.142 - 1.185 0.144 - 83.6 1 2 0 0.0002 10 0 0 0 5.57E+06 1.73E+07 - - - 0.6411 0.9997 221125_WJC_METTL3_EV_vs_WT_F05.07415.07415.2 0.000785 20-Aug K.VTEEGTELSQR.L "sp|Q99996|AKAP9_HUMAN,tr|A0A0A0MRF6|A0A0A0MRF6_HUMAN,tr|A0A7P0TBH8|A0A7P0TBH8_HUMAN,tr|A0A7P0TAX3|A0A7P0TAX3_HUMAN,tr|A0A7P0T9A9|A0A7P0T9A9_HUMAN,tr|A0A7P0T8N5|A0A7P0T8N5_HUMAN,tr|A0A7P0TBI4|A0A7P0TBI4_HUMAN,tr|A0A7P0Z4Q5|A0A7P0Z4Q5_HUMAN,tr|A0A7P0Z4N5|A0A7P0Z4N5_HUMAN,tr|A0A7P0TAD6|A0A7P0TAD6_HUMAN,tr|A0A7P0T939|A0A7P0T939_HUMAN,tr|A0A7P0T928|A0A7P0T928_HUMAN,tr|A0A7P0TAA2|A0A7P0TAA2_HUMAN" 13 1247.5994 0.74 60490 7415 2 1247.598735 624.807 A-kinase anchor protein 9 OS=Homo sapiens OX=9606 GN=AKAP9 PE=1 SV=4 4.25 1802 - 247508 - - - -0.501 - 1.838 0.386 - 227.6 1 2 0 -0.0006 11 0 0 0 3.58E+06 4.83E+06 - - - 3.5384 0.9992 221125_WJC_METTL3_EV_vs_WT_F05.07417.07417.2 0.000118 22-Nov K.QVENAGAIGPSR.F "sp|Q9UHD8|SEPT9_HUMAN,tr|K7EPY1|K7EPY1_HUMAN,tr|K7EJV0|K7EJV0_HUMAN,tr|K7ENL0|K7ENL0_HUMAN" 4 1197.6102 1.01 60491 7417 2 1197.614074 599.8124 Septin-9 OS=Homo sapiens OX=9606 GN=SEPTIN9 PE=1 SV=2 6 1802.2 - 402580 - - - 3.2356 - 2.136 0.481 - 393 1 2 0 0.0039 12 0 0 0 8.26E+06 8.21E+06 - - - 4.5893 0.9995 221125_WJC_METTL3_EV_vs_WT_F05.07419.07419.2 0.111 18-Oct R.TTTGSYIANR.V "sp|P28072|PSB6_HUMAN,tr|I3L3X7|I3L3X7_HUMAN,tr|A0A087X2I4|A0A087X2I4_HUMAN" 3 1082.5356 1 60492 7419 2 1082.535885 542.2751 Proteasome subunit beta type-6 OS=Homo sapiens OX=9606 GN=PSMB6 PE=1 SV=4 8.41 1802.4 - 3.12E+06 - - - 0.2291 - 1.972 0.288 - 586.8 1 2 0 0.0002 10 0 0 0 8.30E+07 8.31E+07 - - - 3.0635 0.9999 221125_WJC_METTL3_EV_vs_WT_F05.07421.07421.2 0.00126 20-Dec K.SVQVNGAATVR.T "tr|H0Y641|H0Y641_HUMAN,tr|H0Y4V9|H0Y4V9_HUMAN" 2 1100.5938 1.51 60494 7421 2 1100.592967 551.3042 La-related protein 4B (Fragment) OS=Homo sapiens OX=9606 GN=LARP4B PE=1 SV=2 9.47 1802.6 - 1.05E+06 - - - -0.7759 - 2.236 0.49 - 603.3 1 2 0 -0.0009 11 0 0 0 4.11E+07 2.72E+07 - - - 4.8367 0.9994 221125_WJC_METTL3_EV_vs_WT_F05.07423.07423.2 0.002 20-Oct K.SVQVNGAATVR[166.11].T "tr|H0Y641|H0Y641_HUMAN,tr|H0Y4V9|H0Y4V9_HUMAN" 2 1110.6021 1.52 60496 7423 2 1110.602897 556.3083 La-related protein 4B (Fragment) OS=Homo sapiens OX=9606 GN=LARP4B PE=1 SV=2 9.47 1802.8 - 901281 - - - 0.7257 - 1.768 0.319 - 254.3 1 2 0 0.0008 11 0 0 0 4.10E+07 2.70E+07 - - - 2.9385 0.9822 221125_WJC_METTL3_EV_vs_WT_F05.07424.07424.3 1.6 Sep-40 K.ILGPQGNTIKR.L sp|Q07666|KHDR1_HUMAN 1 1195.7037 0.85 60497 7424 3 1195.703673 399.5752 "KH domain-containing, RNA-binding, signal transduction-associated protein 1 OS=Homo sapiens OX=9606 GN=KHDRBS1 PE=1 SV=1" 11 1802.9 - 716767 - - - -0.0276 - 1.591 0.156 - 79.8 2 2 0 0 11 0 0 0 7.04E+07 8.32E+07 - - - 1.4591 0.997 221125_WJC_METTL3_EV_vs_WT_F05.07435.07435.2 9.98E-06 20-Sep K.FATC[160.03]SDDGTVR[166.11].L "sp|Q9C0J8|WDR33_HUMAN,tr|C9J8B4|C9J8B4_HUMAN" 2 1237.5273 1.71 60506 7435 2 1237.520626 619.7709 pre-mRNA 3' end processing protein WDR33 OS=Homo sapiens OX=9606 GN=WDR33 PE=1 SV=2 4.21 1804.2 - 1.46E+06 - - - -5.3696 - 1.68 0.598 - 282.5 1 2 0 -0.0066 11 0 0 0 4.25E+07 2.49E+07 - - - 4.8592 0.9831 221125_WJC_METTL3_EV_vs_WT_F05.07436.07436.2 0.000924 22-Jul K.PIPQTPESAGNK[136.11].H "sp|P52948|NUP98_HUMAN,tr|A0A3B3ITD8|A0A3B3ITD8_HUMAN" 2 1245.6445 2.1 60507 7436 2 1245.644245 623.8295 Nuclear pore complex protein Nup98-Nup96 OS=Homo sapiens OX=9606 GN=NUP98 PE=1 SV=4 6.43 1804.3 - 344819 - - - -0.1774 - 1.407 0.499 - 124.2 1 1 0 -0.0002 12 0 0 0 1.88E+08 8.95E+07 - - - 3.625 1 221125_WJC_METTL3_EV_vs_WT_F05.07442.07442.2 2.92E-08 20-Oct K.FATC[160.03]SDDGTVR.L "sp|Q9C0J8|WDR33_HUMAN,tr|C9J8B4|C9J8B4_HUMAN" 2 1227.519 1.71 60510 7442 2 1227.517637 614.7668 pre-mRNA 3' end processing protein WDR33 OS=Homo sapiens OX=9606 GN=WDR33 PE=1 SV=2 4.21 1805 - 1.53E+06 - - - -1.1112 - 2.078 0.682 - 375.6 1 2 0 -0.0014 11 0 0 0 4.25E+07 2.49E+07 - - - 6.0564 0.9957 221125_WJC_METTL3_EV_vs_WT_F05.07449.07449.2 0.136 18-Sep K.AIEENNNFSK[136.11].M "sp|P16949|STMN1_HUMAN,sp|Q93045|STMN2_HUMAN,tr|E5RGX5|E5RGX5_HUMAN" 3 1172.5553 0.86 60515 7449 2 1172.559196 587.2849 Stathmin OS=Homo sapiens OX=9606 GN=STMN1 PE=1 SV=3 4.53 1805.9 - 809022 - - - 3.3082 - 1.656 0.296 - 189.6 1 2 0 0.0039 10 0 0 0 2.43E+07 2.82E+07 - - - 2.634 0.999 221125_WJC_METTL3_EV_vs_WT_F05.07450.07450.2 0.000381 12-Jul R.HYEDFPK[136.11].L sp|O94906|PRP6_HUMAN 1 942.4327 2.74 60516 7450 2 942.431374 472.2236 Pre-mRNA-processing factor 6 OS=Homo sapiens OX=9606 GN=PRPF6 PE=1 SV=1 5.32 1806.1 - 568296 - - - -1.3879 - 1.492 0.328 - 209 1 2 0 -0.0013 7 0 0 0 5.19E+07 1.89E+07 - - - 2.731 0.9989 221125_WJC_METTL3_EV_vs_WT_F05.07451.07451.2 0.0114 20-Jun K.VTEEGTELSQR[166.11].L "sp|Q99996|AKAP9_HUMAN,tr|A0A0A0MRF6|A0A0A0MRF6_HUMAN,tr|A0A7P0TBH8|A0A7P0TBH8_HUMAN,tr|A0A7P0TAX3|A0A7P0TAX3_HUMAN,tr|A0A7P0T9A9|A0A7P0T9A9_HUMAN,tr|A0A7P0T8N5|A0A7P0T8N5_HUMAN,tr|A0A7P0TBI4|A0A7P0TBI4_HUMAN,tr|A0A7P0Z4Q5|A0A7P0Z4Q5_HUMAN,tr|A0A7P0Z4N5|A0A7P0Z4N5_HUMAN,tr|A0A7P0TAD6|A0A7P0TAD6_HUMAN,tr|A0A7P0T939|A0A7P0T939_HUMAN,tr|A0A7P0T928|A0A7P0T928_HUMAN,tr|A0A7P0TAA2|A0A7P0TAA2_HUMAN" 13 1257.6076 0.74 60517 7451 2 1257.608191 629.8111 A-kinase anchor protein 9 OS=Homo sapiens OX=9606 GN=AKAP9 PE=1 SV=4 4.25 1806.2 - 128675 - - - 0.4461 - 1.456 0.31 - 100.8 1 2 0 0.0006 11 0 0 0 3.58E+06 4.83E+06 - - - 2.3468 0.9999 221125_WJC_METTL3_EV_vs_WT_F05.07453.07453.2 1.06E-05 20-Nov R.IPSTDTQVQPK.L "sp|Q9ULV3|CIZ1_HUMAN,tr|Q5SYW2|Q5SYW2_HUMAN,tr|F5H2X7|F5H2X7_HUMAN,tr|H0Y5D5|H0Y5D5_HUMAN,tr|A0A494C0L7|A0A494C0L7_HUMAN,tr|Q9BTG3|Q9BTG3_HUMAN" 6 1212.635 2.9 60518 7453 2 1212.634594 607.3248 Cip1-interacting zinc finger protein OS=Homo sapiens OX=9606 GN=CIZ1 PE=1 SV=2 5.84 1806.4 - 1.26E+06 - - - -0.3488 - 2.167 0.532 - 504.3 1 2 0 -0.0004 11 0 0 0 6.03E+08 2.08E+08 - - - 5.0623 0.9724 221125_WJC_METTL3_EV_vs_WT_F05.07454.07454.3 0.663 Nov-36 R.ATLEMVNHEK.A "sp|P07197|NFM_HUMAN,tr|E7ESP9|E7ESP9_HUMAN,tr|E7EMV2|E7EMV2_HUMAN" 3 1170.5703 3.12 60519 7454 3 1170.568142 391.1974 Neurofilament medium polypeptide OS=Homo sapiens OX=9606 GN=NEFM PE=1 SV=3 5.4 1806.5 - 2.15E+06 - - - -1.8504 - 1.951 0.089 - 179.9 1 2 0 -0.0022 10 0 0 0 8.69E+07 2.78E+07 - - - 1.4835 0.9997 221125_WJC_METTL3_EV_vs_WT_F05.07455.07455.2 5.86E-05 20-Aug R.FVPPQTSSGNR.F "sp|Q6KC79|NIPBL_HUMAN,tr|A0A590UJS4|A0A590UJS4_HUMAN" 2 1188.5887 0.81 60520 7455 2 1188.587082 595.3016 Nipped-B-like protein OS=Homo sapiens OX=9606 GN=NIPBL PE=1 SV=2 9.75 1806.6 - 992589 - - - -1.3916 - 1.619 0.509 - 116.6 1 2 0 -0.0017 11 0 0 0 5.60E+07 6.95E+07 - - - 4.1034 0.9991 221125_WJC_METTL3_EV_vs_WT_F05.07457.07457.2 0.00683 18-Jul R.ATLEMVNHEK[136.11].A "sp|P07197|NFM_HUMAN,tr|E7ESP9|E7ESP9_HUMAN,tr|E7EMV2|E7EMV2_HUMAN" 3 1178.5845 2.09 60522 7457 2 1178.586136 590.2995 Neurofilament medium polypeptide OS=Homo sapiens OX=9606 GN=NEFM PE=1 SV=3 5.4 1806.9 - 257140 - - - 1.3813 - 1.522 0.366 - 112.4 1 2 0 0.0016 10 0 0 0 1.53E+07 7.32E+06 - - - 2.9162 0.9997 221125_WJC_METTL3_EV_vs_WT_F05.07460.07460.3 0.000326 Nov-40 K.ILGPQGNTIK[136.11]R[166.11].L sp|Q07666|KHDR1_HUMAN 1 1213.7262 0.84 60523 7460 3 1213.724795 405.5827 "KH domain-containing, RNA-binding, signal transduction-associated protein 1 OS=Homo sapiens OX=9606 GN=KHDRBS1 PE=1 SV=1" 11 1807.3 - 1.60E+06 - - - -1.1378 - 2.101 0.322 - 133.5 1 2 0 -0.0014 11 0 0 0 7.02E+07 8.31E+07 - - - 4.2387 0.9997 221125_WJC_METTL3_EV_vs_WT_F05.07461.07461.2 0.00183 15/18 R.R[166.11]ISAVSVAER[166.11].V sp|Q08211|DHX9_HUMAN 1 1106.6311 0.93 60524 7461 2 1106.630284 554.3228 ATP-dependent RNA helicase A OS=Homo sapiens OX=9606 GN=DHX9 PE=1 SV=4 9.6 1807.4 - 1.62E+06 - - - -0.7338 - 2.379 0.302 - 366 1 2 0 -0.0008 10 0 0 0 8.38E+07 9.03E+07 - - - 3.6905 0.9993 221125_WJC_METTL3_EV_vs_WT_F05.07462.07462.2 0.003 16-Jul K.EGIPPDQQR.L "sp|P62979|RS27A_HUMAN,sp|P0CG48|UBC_HUMAN,sp|P0CG48|UBC_HUMAN,sp|P0CG48|UBC_HUMAN,sp|P0CG48|UBC_HUMAN,sp|P0CG48|UBC_HUMAN,sp|P0CG48|UBC_HUMAN,sp|P0CG48|UBC_HUMAN,sp|P0CG48|UBC_HUMAN,sp|P0CG48|UBC_HUMAN,sp|P0CG47|UBB_HUMAN,sp|P0CG47|UBB_HUMAN,sp|P0CG47|UBB_HUMAN,sp|P62987|RL40_HUMAN,tr|F5H388|F5H388_HUMAN,tr|F5H388|F5H388_HUMAN,tr|F5GYU3|F5GYU3_HUMAN,tr|F5GYU3|F5GYU3_HUMAN,tr|B4DV12|B4DV12_HUMAN,tr|B4DV12|B4DV12_HUMAN,tr|J3QSA3|J3QSA3_HUMAN,tr|Q5PY61|Q5PY61_HUMAN,tr|Q5PY61|Q5PY61_HUMAN,tr|Q5PY61|Q5PY61_HUMAN,tr|F5H2Z3|F5H2Z3_HUMAN,tr|F5H2Z3|F5H2Z3_HUMAN,tr|M0R2S1|M0R2S1_HUMAN,tr|J3QS39|J3QS39_HUMAN,tr|J3QTR3|J3QTR3_HUMAN,tr|Q96C32|Q96C32_HUMAN,tr|Q96C32|Q96C32_HUMAN,tr|Q96C32|Q96C32_HUMAN,tr|Q96C32|Q96C32_HUMAN,tr|M0R1V7|M0R1V7_HUMAN,tr|F5H747|F5H747_HUMAN,tr|F5H747|F5H747_HUMAN,tr|F5GXK7|F5GXK7_HUMAN,tr|F5GXK7|F5GXK7_HUMAN,tr|M0R1M6|M0R1M6_HUMAN,tr|F5H6Q2|F5H6Q2_HUMAN,tr|F5H6Q2|F5H6Q2_HUMAN,tr|F5GZ39|F5GZ39_HUMAN,tr|J3QKN0|J3QKN0_HUMAN,tr|J3QKN0|J3QKN0_HUMAN,tr|J3QKN0|J3QKN0_HUMAN,tr|F5H265|F5H265_HUMAN,tr|F5H265|F5H265_HUMAN,tr|A0A2R8Y422|A0A2R8Y422_HUMAN" 48 1038.5094 0.65 60525 7462 2 1038.509502 520.262 Ubiquitin-40S ribosomal protein S27a OS=Homo sapiens OX=9606 GN=RPS27A PE=1 SV=2 4.37 1807.5 - 652028 - - - 0.0761 - 1.44 0.36 - 157.7 1 2 0 0.0001 9 0 0 0 2.32E+07 3.58E+07 - - - 2.7549 0.9996 221125_WJC_METTL3_EV_vs_WT_F05.07466.07466.2 0.0209 18-Nov R.RISAVSVAER.V sp|Q08211|DHX9_HUMAN 1 1086.6146 0.92 60527 7466 2 1086.6147 544.3146 ATP-dependent RNA helicase A OS=Homo sapiens OX=9606 GN=DHX9 PE=1 SV=4 9.6 1808 - 1.58E+06 - - - 0.1325 - 2.018 0.318 - 162.5 1 2 0 0.0001 10 0 0 0 8.27E+07 9.02E+07 - - - 3.3495 0.9903 221125_WJC_METTL3_EV_vs_WT_F05.07468.07468.2 0.239 14-Aug K.HLEEIVEK[136.11].L "sp|Q9P2E9|RRBP1_HUMAN,tr|A0A087WU26|A0A087WU26_HUMAN,tr|A0A087WVV2|A0A087WVV2_HUMAN,tr|F8W7S5|F8W7S5_HUMAN" 4 1003.543 1.08 60529 7468 2 1003.545708 502.7788 Ribosome-binding protein 1 OS=Homo sapiens OX=9606 GN=RRBP1 PE=1 SV=5 4.75 1808.2 - 452197 - - - 2.7373 - 1.609 0.152 - 188.1 1 2 0 0.0027 8 0 0 0 8.22E+07 7.61E+07 - - - 1.5972 0.9678 221125_WJC_METTL3_EV_vs_WT_F05.07476.07476.2 0.00253 22-Jul K.K[136.11]GPGEVAGTVTG.Q "sp|Q86U44|MTA70_HUMAN,tr|F5H6D8|F5H6D8_HUMAN,tr|H0YFV6|H0YFV6_HUMAN,tr|B4DTN4|B4DTN4_HUMAN" 4 1079.5702 0.04 60535 7476 2 1079.569918 540.7924 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 6 1809.2 - 1.83E+06 - - - -0.2964 - 1.541 0.371 - 120.3 1 1 0 -0.0003 12 0 0 0 5.03E+06 1.22E+08 - - - 2.9189 0.9998 221125_WJC_METTL3_EV_vs_WT_F05.07478.07478.2 0.00663 14-Nov K.HLEEIVEK.L "sp|Q9P2E9|RRBP1_HUMAN,tr|A0A087WU26|A0A087WU26_HUMAN,tr|A0A087WVV2|A0A087WVV2_HUMAN,tr|F8W7S5|F8W7S5_HUMAN" 4 995.5288 0.88 60537 7478 2 995.52827 498.7717 Ribosome-binding protein 1 OS=Homo sapiens OX=9606 GN=RRBP1 PE=1 SV=5 4.75 1809.3 - 820829 - - - -0.4932 - 2.012 0.421 - 462.4 1 2 0 -0.0005 8 0 0 0 8.49E+07 9.60E+07 - - - 4.2589 0.9627 221125_WJC_METTL3_EV_vs_WT_F05.07479.07479.2 0.0503 16-Jul Q.GLVLDHGAR[166.11].H "sp|Q92526|TCPW_HUMAN,sp|P40227|TCPZ_HUMAN,tr|J3KRI6|J3KRI6_HUMAN" 3 946.5224 0.26 60538 7479 2 946.522183 474.2685 T-complex protein 1 subunit zeta-2 OS=Homo sapiens OX=9606 GN=CCT6B PE=1 SV=5 6.74 1809.4 - 695900 - - - -0.2124 - 1.798 0.275 - 220.9 1 1 0 -0.0002 9 0 0 0 5.89E+06 2.26E+07 - - - 2.7694 0.9997 221125_WJC_METTL3_EV_vs_WT_F05.07482.07482.2 0.0128 12-Sep R.HYEDFPK.L sp|O94906|PRP6_HUMAN 1 934.4185 2.75 60539 7482 2 934.418544 468.2165 Pre-mRNA-processing factor 6 OS=Homo sapiens OX=9606 GN=PRPF6 PE=1 SV=1 5.32 1809.8 - 1.38E+06 - - - 0.0664 - 1.617 0.401 - 323.6 1 2 0 0.0001 7 0 0 0 5.20E+07 1.89E+07 - - - 3.5255 0.9993 221125_WJC_METTL3_EV_vs_WT_F05.07485.07485.2 0.000432 20-Aug K.VQDSAPVETPR[166.11].G "sp|P09601|HMOX1_HUMAN,tr|A0A7I2V3M0|A0A7I2V3M0_HUMAN,tr|A0A7I2V277|A0A7I2V277_HUMAN" 3 1207.6072 1.98 60542 7485 2 1207.610444 604.8109 Heme oxygenase 1 OS=Homo sapiens OX=9606 GN=HMOX1 PE=1 SV=1 4.37 1810.2 - 347478 - - - 2.6565 - 1.821 0.464 - 225.9 1 2 0 0.0032 11 0 0 0 1.02E+08 5.15E+07 - - - 4.0886 0.864 221125_WJC_METTL3_EV_vs_WT_F05.07486.07486.2 0.0421 18-Sep K.EAAEVLQNNR.R "sp|P61081|UBC12_HUMAN,tr|M0QX69|M0QX69_HUMAN" 2 1142.568 0.33 60543 7486 2 1143.568044 572.2913 NEDD8-conjugating enzyme Ubc12 OS=Homo sapiens OX=9606 GN=UBE2M PE=1 SV=1 4.53 1810.3 - 343819 - - - 875.2599 - 1.696 0.303 - 152.3 1 2 0 1 10 0 0 0 8.61E+06 2.57E+07 - - - 2.4395 0.9994 221125_WJC_METTL3_EV_vs_WT_F05.07488.07488.2 0.00119 22-Oct R.EMEAPGGPSEDR.G sp|Q9C0J8|WDR33_HUMAN 1 1273.5245 1.99 60545 7488 2 1273.520728 637.7695 pre-mRNA 3' end processing protein WDR33 OS=Homo sapiens OX=9606 GN=WDR33 PE=1 SV=2 4 1810.6 - 290848 - - - -2.9462 - 1.743 0.561 - 297.1 1 2 0 -0.0038 12 0 0 0 5.87E+06 2.95E+06 - - - 4.6453 0.9992 221125_WJC_METTL3_EV_vs_WT_F05.07489.07489.2 0.186 16-Oct K.SLDGVTNDR.T "sp|Q9UBM7|DHCR7_HUMAN,tr|E9PIP9|E9PIP9_HUMAN,tr|E9PJ54|E9PJ54_HUMAN,tr|E9PRL8|E9PRL8_HUMAN,tr|E9PM00|E9PM00_HUMAN,tr|A0A804HI25|A0A804HI25_HUMAN,tr|A0A804HJQ7|A0A804HJQ7_HUMAN,tr|A0A804HJI8|A0A804HJI8_HUMAN,tr|A0A804HL56|A0A804HL56_HUMAN,tr|E9PQ71|E9PQ71_HUMAN" 10 975.4621 1.13 60546 7489 2 975.463043 488.7383 7-dehydrocholesterol reductase OS=Homo sapiens OX=9606 GN=DHCR7 PE=1 SV=1 4.21 1810.7 - 273185 - - - 0.9278 - 1.806 0.272 - 297.7 1 2 0 0.0009 9 0 0 0 1.05E+07 9.29E+06 - - - 2.7598 0.9997 221125_WJC_METTL3_EV_vs_WT_F05.07492.07492.2 0.0321 12-Aug R.HVYNLPK.G sp|Q96SK2|TM209_HUMAN 1 869.4759 1.75 60548 7492 2 869.476313 435.7452 Transmembrane protein 209 OS=Homo sapiens OX=9606 GN=TMEM209 PE=1 SV=2 8.6 1811.2 - 564746 - - - 0.4313 - 1.748 0.369 - 252.4 1 2 0 0.0004 7 0 0 0 2.28E+07 1.30E+07 - - - 3.5359 0.9672 221125_WJC_METTL3_EV_vs_WT_F05.07494.07494.2 0.602 18-Jul K.ALEHVPNSVR.L sp|O94906|PRP6_HUMAN 1 1120.5989 3.16 60549 7494 2 1120.594539 561.3067 Pre-mRNA-processing factor 6 OS=Homo sapiens OX=9606 GN=PRPF6 PE=1 SV=1 6.79 1811.4 - 803126 - - - -3.897 - 1.501 0.15 - 77.4 1 2 0 -0.0044 10 0 0 0 1.91E+07 6.04E+06 - - - 1.2812 0.9913 221125_WJC_METTL3_EV_vs_WT_F05.07496.07496.2 0.00346 18-Sep R.SVTTEPSSLK.S "sp|Q6PJT7|ZC3HE_HUMAN,tr|G3V3Y4|G3V3Y4_HUMAN,tr|G3V473|G3V473_HUMAN,tr|G3V256|G3V256_HUMAN,tr|G3V572|G3V572_HUMAN,tr|G3V3R9|G3V3R9_HUMAN,tr|G3V240|G3V240_HUMAN,tr|A0A3B3IT62|A0A3B3IT62_HUMAN" 8 1047.5448 0.35 60551 7496 2 1047.549228 524.7797 Zinc finger CCCH domain-containing protein 14 OS=Homo sapiens OX=9606 GN=ZC3H14 PE=1 SV=1 5.72 1811.6 - 1.04E+06 - - - 4.2223 - 1.458 0.339 - 195.7 1 2 0 0.0044 10 0 0 0 3.34E+07 9.56E+07 - - - 2.596 0.9997 221125_WJC_METTL3_EV_vs_WT_F05.07499.07499.2 0.0122 22-Jul R.EMEAPGGPSEDR[166.11].G sp|Q9C0J8|WDR33_HUMAN 1 1283.5328 1.94 60554 7499 2 1283.533781 642.7737 pre-mRNA 3' end processing protein WDR33 OS=Homo sapiens OX=9606 GN=WDR33 PE=1 SV=2 4 1812 - 118146 - - - 0.8033 - 1.393 0.503 - 137.9 1 2 0 0.001 12 0 0 0 5.71E+06 2.95E+06 - - - 3.628 0.9947 221125_WJC_METTL3_EV_vs_WT_F05.07506.07506.2 0.134 14-Aug R.HLFTPADK[136.11].R "sp|Q9Y2L1|RRP44_HUMAN,tr|F2Z2C0|F2Z2C0_HUMAN,tr|G3V1J5|G3V1J5_HUMAN" 3 935.4956 2.04 60558 7506 2 935.495509 468.7551 Exosome complex exonuclease RRP44 OS=Homo sapiens OX=9606 GN=DIS3 PE=1 SV=2 6.74 1812.8 - 1.43E+06 - - - -0.1154 - 1.118 0.227 - 154.4 1 2 0 -0.0001 8 0 0 0 4.16E+07 2.04E+07 - - - 1.054 0.9998 221125_WJC_METTL3_EV_vs_WT_F05.07511.07511.2 0.0014 16-Sep R.C[160.03]NLAC[160.03]TPPR[166.11].H "sp|P46379|BAG6_HUMAN,tr|A0A7I2V508|A0A7I2V508_HUMAN,tr|A0A0G2JJM1|A0A0G2JJM1_HUMAN,tr|X6REW1|X6REW1_HUMAN,tr|A0A7P0MQS5|A0A7P0MQS5_HUMAN,tr|F6S6P2|F6S6P2_HUMAN,tr|A0A0G2JL47|A0A0G2JL47_HUMAN,tr|A0A024RCR6|A0A024RCR6_HUMAN,tr|A0A0G2JK23|A0A0G2JK23_HUMAN" 9 1097.4986 1.94 60560 7511 2 1097.498971 549.7566 Large proline-rich protein BAG6 OS=Homo sapiens OX=9606 GN=BAG6 PE=1 SV=2 8.07 1813.5 - 277040 - - - 0.38 - 2.031 0.444 - 462.9 1 2 0 0.0004 9 0 0 0 2.02E+07 1.04E+07 - - - 4.3701 0.9984 221125_WJC_METTL3_EV_vs_WT_F05.07517.07517.2 0.113 12-Sep R.HVYNLPK[136.11].G sp|Q96SK2|TM209_HUMAN 1 877.4901 1.94 60564 7517 2 877.491273 439.7523 Transmembrane protein 209 OS=Homo sapiens OX=9606 GN=TMEM209 PE=1 SV=2 8.6 1814.3 - 456268 - - - 1.2935 - 1.477 0.277 - 375.1 1 2 0 0.0011 7 0 0 0 2.27E+07 1.17E+07 - - - 2.3223 0.9987 221125_WJC_METTL3_EV_vs_WT_F05.07519.07519.2 0.00324 24-Jun K.IISPGSSTPSSTR.S sp|Q5VT52|RPRD2_HUMAN 1 1288.6623 1.42 60566 7519 2 1288.664136 645.3384 Regulation of nuclear pre-mRNA domain-containing protein 2 OS=Homo sapiens OX=9606 GN=RPRD2 PE=1 SV=1 9.75 1814.5 - 87160.2 - - - 1.4294 - 1.43 0.359 - 78.9 1 2 0 0.0018 13 0 0 0 6.22E+06 4.38E+06 - - - 2.61 0.9978 221125_WJC_METTL3_EV_vs_WT_F05.07521.07521.2 0.224 14-Aug R.NLEISQQK[136.11].G sp|Q9H6S0|YTDC2_HUMAN 1 966.5226 3.38 60567 7521 2 966.523893 484.2686 3'-5' RNA helicase YTHDC2 OS=Homo sapiens OX=9606 GN=YTHDC2 PE=1 SV=2 6 1814.7 - 554870 - - - 1.3792 - 1.454 0.26 - 209.1 1 2 0 0.0013 8 0 0 0 4.80E+07 1.42E+07 - - - 2.0899 0.9973 221125_WJC_METTL3_EV_vs_WT_F05.07523.07523.2 0.558 12-Jul R.K[136.11]VWDQVK[136.11].A "sp|Q969G3|SMCE1_HUMAN,tr|A0A2R8Y855|A0A2R8Y855_HUMAN,tr|A0A2R8YEB8|A0A2R8YEB8_HUMAN,tr|A0A2R8YES3|A0A2R8YES3_HUMAN,tr|A0A2U3TZQ7|A0A2U3TZQ7_HUMAN,tr|A0A2R8Y7U4|A0A2R8Y7U4_HUMAN,tr|B4DGM3|B4DGM3_HUMAN,tr|A0A2R8YD78|A0A2R8YD78_HUMAN,tr|J3QKS7|J3QKS7_HUMAN,tr|A0A2R8Y4T4|A0A2R8Y4T4_HUMAN,tr|A0A2R8Y7I9|A0A2R8Y7I9_HUMAN,tr|J3QR61|J3QR61_HUMAN,tr|A0A2R8Y765|A0A2R8Y765_HUMAN,tr|J3KT85|J3KT85_HUMAN,tr|J3QKX6|J3QKX6_HUMAN,tr|A0A2R8YFC8|A0A2R8YFC8_HUMAN" 16 917.5306 10.73 60568 7523 2 917.531316 459.7726 SWI\SNF-related matrix-associated actin-dependent regulator of chromatin subfamily E member 1 OS=Homo sapiens OX=9606 GN=SMARCE1 PE=1 SV=2 8.59 1815 - 773349 - - - 0.8327 - 1.432 0.21 - 182.6 1 2 0 0.0008 7 0 0 0 1.76E+08 1.64E+07 - - - 1.7296 0.9636 221125_WJC_METTL3_EV_vs_WT_F05.07524.07524.2 0.00132 20-Nov C.STVLC[160.03]QPTGGK.A "sp|Q71UM5|RS27L_HUMAN,sp|P42677|RS27_HUMAN,tr|H0YMV8|H0YMV8_HUMAN,tr|C9J1C5|C9J1C5_HUMAN,tr|C9JLI6|C9JLI6_HUMAN" 5 1146.5703 0.32 60569 7524 2 1146.573326 574.2924 40S ribosomal protein S27-like OS=Homo sapiens OX=9606 GN=RPS27L PE=1 SV=3 7.94 1815.1 - 477216 - - - 2.6313 - 2.066 0.439 - 525.2 1 1 0 0.003 11 0 0 0 9.20E+06 2.84E+07 - - - 4.2455 0.9996 221125_WJC_METTL3_EV_vs_WT_F05.07526.07526.2 0.0196 16-Sep K.TQLAVC[160.03]QQR[166.11].L "sp|Q02790|FKBP4_HUMAN,tr|H0YFG2|H0YFG2_HUMAN" 2 1112.5636 1.01 60571 7526 2 1112.563974 557.2891 Peptidyl-prolyl cis-trans isomerase FKBP4 OS=Homo sapiens OX=9606 GN=FKBP4 PE=1 SV=3 7.91 1815.3 - 370837 - - - 0.3389 - 1.864 0.321 - 264.6 1 2 0 0.0004 9 0 0 0 1.21E+07 1.20E+07 - - - 3.2134 0.9998 221125_WJC_METTL3_EV_vs_WT_F05.07527.07527.2 4.33E-05 20-Nov K.NVAEALGHSPK[136.11].D sp|Q8IU81|I2BP1_HUMAN 1 1129.5971 1.05 60572 7527 2 1129.598866 565.8058 Interferon regulatory factor 2-binding protein 1 OS=Homo sapiens OX=9606 GN=IRF2BP1 PE=1 SV=1 6.75 1815.5 - 257967 - - - 1.5439 - 1.978 0.501 - 337 1 2 0 0.0017 11 0 0 0 1.19E+07 1.14E+07 - - - 4.586 0.9985 221125_WJC_METTL3_EV_vs_WT_F05.07529.07529.2 0.000153 22-Sep R.LLQAETASNSAR[166.11].A "sp|Q14980|NUMA1_HUMAN,tr|H0YFY6|H0YFY6_HUMAN" 2 1269.6552 1.3 60574 7529 2 1269.659309 635.8349 Nuclear mitotic apparatus protein 1 OS=Homo sapiens OX=9606 GN=NUMA1 PE=1 SV=2 6 1815.7 - 167128 - - - 3.1977 - 1.884 0.399 - 310.4 1 2 0 0.0041 12 0 0 0 6.15E+06 4.73E+06 - - - 3.6533 0.9965 221125_WJC_METTL3_EV_vs_WT_F05.07532.07532.2 0.113 14-Jul K.TIQVPQQK[136.11].A "sp|Q9BY77|PDIP3_HUMAN,tr|F8WCX5|F8WCX5_HUMAN" 2 948.5484 1.36 60575 7532 2 948.549595 475.2815 Polymerase delta-interacting protein 3 OS=Homo sapiens OX=9606 GN=POLDIP3 PE=1 SV=2 8.41 1816.2 - 1.02E+06 - - - 1.2799 - 1.394 0.221 - 160.2 1 2 0 0.0012 8 0 0 0 1.45E+09 1.06E+09 - - - 1.6748 0.9164 221125_WJC_METTL3_EV_vs_WT_F05.07534.07534.2 0.0669 22-Jul K.KGPGEVAGTVTG.Q "sp|Q86U44|MTA70_HUMAN,tr|F5H6D8|F5H6D8_HUMAN,tr|H0YFV6|H0YFV6_HUMAN,tr|B4DTN4|B4DTN4_HUMAN" 4 1071.556 0.04 60577 7534 2 1071.557215 536.7853 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 6 1816.4 - 255274 - - - 1.0984 - 1.405 0.319 - 90.9 1 1 0 0.0012 12 0 0 0 5.03E+06 1.15E+08 - - - 2.2915 0.9978 221125_WJC_METTL3_EV_vs_WT_F05.07538.07538.2 0.192 14-Jul R.NLEISQQK.G sp|Q9H6S0|YTDC2_HUMAN 1 958.5084 0.93 60579 7538 2 958.509119 480.2615 3'-5' RNA helicase YTHDC2 OS=Homo sapiens OX=9606 GN=YTHDC2 PE=1 SV=2 6 1817 - 702026 - - - 0.7919 - 1.487 0.221 - 194 1 2 0 0.0008 8 0 0 0 6.98E+06 7.47E+06 - - - 1.8697 0.9841 221125_WJC_METTL3_EV_vs_WT_F05.07539.07539.2 0.0139 12-Sep K.HLESFPK.Q sp|Q92665|RT31_HUMAN 1 856.4443 2.35 60580 7539 2 856.448768 429.2294 "28S ribosomal protein S31, mitochondrial OS=Homo sapiens OX=9606 GN=MRPS31 PE=1 SV=3" 6.75 1817.1 - 464125 - - - 5.2134 - 1.51 0.318 - 361.5 1 2 0 0.0045 7 0 0 0 6.76E+07 2.88E+07 - - - 2.6941 0.9977 221125_WJC_METTL3_EV_vs_WT_F05.07540.07540.2 0.00277 14-Jul K.DC[160.03]YPAVQK[136.11].T "sp|Q14974|IMB1_HUMAN,tr|J3QKQ5|J3QKQ5_HUMAN,tr|J3KTM9|J3KTM9_HUMAN" 3 987.4575 1.1 60581 7540 2 987.459251 494.736 Importin subunit beta-1 OS=Homo sapiens OX=9606 GN=KPNB1 PE=1 SV=2 5.83 1817.2 - 598258 - - - 1.756 - 1.191 0.364 - 231 1 2 0 0.0017 8 0 0 0 4.22E+07 3.83E+07 - - - 2.2561 0.9992 221125_WJC_METTL3_EV_vs_WT_F05.07542.07542.2 0.00248 26-Jul R.AVASQPDSVDAAER[166.11].A "sp|Q9NVE7|PANK4_HUMAN,tr|E9PHT6|E9PHT6_HUMAN,tr|H0YA26|H0YA26_HUMAN" 3 1424.6771 1.08 60583 7542 2 1424.675272 713.3458 4'-phosphopantetheine phosphatase OS=Homo sapiens OX=9606 GN=PANK4 PE=1 SV=1 4.03 1817.5 - 74635.1 - - - -1.2873 - 1.517 0.379 - 119.6 1 2 0 -0.0018 14 0 0 0 1.24E+06 1.15E+06 - - - 2.8855 0.9996 221125_WJC_METTL3_EV_vs_WT_F05.07546.07546.3 0.00141 Dec-36 K.SMQNHAAVFR.V "sp|P31040|SDHA_HUMAN,tr|A0A087X1I3|A0A087X1I3_HUMAN" 2 1159.5557 0.32 60585 7546 3 1159.558953 387.5258 "Succinate dehydrogenase [ubiquinone] flavoprotein subunit, mitochondrial OS=Homo sapiens OX=9606 GN=SDHA PE=1 SV=2" 9.49 1818 - 540005 - - - 2.839 - 1.839 0.416 - 218.6 1 2 0 0.0033 10 0 0 0 1.29E+07 4.01E+07 - - - 4.9563 0.9844 221125_WJC_METTL3_EV_vs_WT_F05.07547.07547.2 1.47 16-Aug K.GGYTLDSNK.G sp|Q08554|DSC1_HUMAN 1 953.4454 0.81 60586 7547 2 953.443581 477.73 Desmocollin-1 OS=Homo sapiens OX=9606 GN=DSC1 PE=1 SV=2 5.83 1818.1 - 386989 - - - -1.934 - 0.983 0.246 - 165.9 1 2 0 -0.0018 9 0 0 0 7.43E+06 9.20E+06 - - - 0.8078 0.9999 221125_WJC_METTL3_EV_vs_WT_F05.07549.07549.2 5.69E-05 20-Sep R.VAELSATQC[160.03]C[160.03]K[136.11].N "sp|Q5TAQ9|DCAF8_HUMAN,tr|V9GY54|V9GY54_HUMAN" 2 1273.5886 2.17 60588 7549 2 1273.589334 637.8016 DDB1- and CUL4-associated factor 8 OS=Homo sapiens OX=9606 GN=DCAF8 PE=1 SV=1 5.96 1818.4 - 152627 - - - 0.57 - 1.928 0.552 - 280 1 2 0 0.0007 11 0 0 0 8.52E+06 3.93E+06 - - - 4.8938 0.9984 221125_WJC_METTL3_EV_vs_WT_F05.07551.07551.2 0.164 20-Jul R.NSLVTGGEDDR[166.11].M "sp|Q8WVM7|STAG1_HUMAN,tr|Q68DW7|Q68DW7_HUMAN" 2 1171.5345 3.84 60590 7551 2 1171.535991 586.7745 Cohesin subunit SA-1 OS=Homo sapiens OX=9606 GN=STAG1 PE=1 SV=3 4.03 1818.6 - 130560 - - - 1.3026 - 1.559 0.283 - 156.6 1 2 0 0.0015 11 0 0 0 8.80E+06 2.29E+06 - - - 2.332 0.9993 221125_WJC_METTL3_EV_vs_WT_F05.07556.07556.2 0.0465 18-Oct R.SGPASTFNDR[166.11].V "sp|Q9P2J5|SYLC_HUMAN,tr|A0A6I8PIV1|A0A6I8PIV1_HUMAN,tr|A0A6I8PRS0|A0A6I8PRS0_HUMAN,tr|A0A6I8PLB8|A0A6I8PLB8_HUMAN,tr|A0A6I8PIP7|A0A6I8PIP7_HUMAN,tr|A0A6I8PIT3|A0A6I8PIT3_HUMAN,tr|A0A6I8PLB3|A0A6I8PLB3_HUMAN,tr|A0A6I8PS05|A0A6I8PS05_HUMAN,tr|B4DER1|B4DER1_HUMAN,tr|A0A6I8PL42|A0A6I8PL42_HUMAN" 10 1060.4813 1.54 60593 7556 2 1060.483951 531.2479 "Leucine--tRNA ligase, cytoplasmic OS=Homo sapiens OX=9606 GN=LARS1 PE=1 SV=2" 5.55 1819.2 - 780080 - - - 2.4932 - 2.128 0.39 - 489.4 1 2 0 0.0026 10 0 0 0 4.66E+07 3.02E+07 - - - 4.0287 0.9993 221125_WJC_METTL3_EV_vs_WT_F05.07557.07557.2 0.091 14-Jun R.DC[160.03]ATFC[160.03]AK.K sp|Q13948|CASP_HUMAN 1 971.3841 0.56 60594 7557 2 971.385395 486.6993 Protein CASP OS=Homo sapiens OX=9606 GN=CUX1 PE=1 SV=2 5.82 1819.4 - 199906 - - - 1.3455 - 1.216 0.479 - 122.9 1 2 0 0.0013 8 0 0 0 2.16E+06 3.85E+06 - - - 3.1683 0.9997 221125_WJC_METTL3_EV_vs_WT_F05.07558.07558.2 6.21E-05 20-Sep R.QMGQPC[160.03]DAYQK.R sp|P15924|DESP_HUMAN 1 1324.554 999 60595 7558 2 1324.556563 663.2843 Desmoplakin OS=Homo sapiens OX=9606 GN=DSP PE=1 SV=3 5.83 1819.5 - 189830 - - - 1.9297 - 1.817 0.537 - 257.5 1 2 0 0.0026 11 0 0 0 8.13E+06 0.00E+00 - - - 4.622 0.9968 221125_WJC_METTL3_EV_vs_WT_F05.07561.07561.2 0.0267 20-Jun K.IFEEQGQTQEK[136.11].C sp|O00459|P85B_HUMAN 1 1343.6449 0.04 60598 7561 2 1343.644469 672.8297 Phosphatidylinositol 3-kinase regulatory subunit beta OS=Homo sapiens OX=9606 GN=PIK3R2 PE=1 SV=2 4.25 1819.9 - 83132.9 - - - -0.291 - 1.105 0.287 - 39.9 1 2 0 -0.0004 11 0 0 0 4.81E+04 1.12E+06 - - - 1.4308 0.9998 221125_WJC_METTL3_EV_vs_WT_F05.07567.07567.2 0.0112 16-Nov K.TQLAVC[160.03]QQR.L "sp|Q02790|FKBP4_HUMAN,tr|H0YFG2|H0YFG2_HUMAN" 2 1102.5553 1 60602 7567 2 1102.556564 552.2849 Peptidyl-prolyl cis-trans isomerase FKBP4 OS=Homo sapiens OX=9606 GN=FKBP4 PE=1 SV=3 7.91 1820.7 - 903375 - - - 1.1219 - 2.128 0.463 - 582.6 1 2 0 0.0012 9 0 0 0 1.20E+07 1.20E+07 - - - 4.6451 0.9992 221125_WJC_METTL3_EV_vs_WT_F05.07568.07568.2 9.82E-06 18-Nov R.SGPASTFNDR.V "sp|Q9P2J5|SYLC_HUMAN,tr|A0A6I8PIV1|A0A6I8PIV1_HUMAN,tr|A0A6I8PRS0|A0A6I8PRS0_HUMAN,tr|A0A6I8PLB8|A0A6I8PLB8_HUMAN,tr|A0A6I8PIP7|A0A6I8PIP7_HUMAN,tr|A0A6I8PIT3|A0A6I8PIT3_HUMAN,tr|A0A6I8PLB3|A0A6I8PLB3_HUMAN,tr|A0A6I8PS05|A0A6I8PS05_HUMAN,tr|B4DER1|B4DER1_HUMAN,tr|A0A6I8PL42|A0A6I8PL42_HUMAN" 10 1050.473 1.09 60603 7568 2 1050.474444 526.2438 "Leucine--tRNA ligase, cytoplasmic OS=Homo sapiens OX=9606 GN=LARS1 PE=1 SV=2" 5.55 1820.7 - 712836 - - - 1.3394 - 1.807 0.308 - 436.3 1 2 0 0.0014 10 0 0 0 3.66E+07 3.35E+07 - - - 2.967 0.9994 221125_WJC_METTL3_EV_vs_WT_F05.07571.07571.2 0.00741 16-Jul R.C[160.03]NLAC[160.03]TPPR.H "sp|P46379|BAG6_HUMAN,tr|A0A7I2V508|A0A7I2V508_HUMAN,tr|A0A0G2JJM1|A0A0G2JJM1_HUMAN,tr|X6REW1|X6REW1_HUMAN,tr|A0A7P0MQS5|A0A7P0MQS5_HUMAN,tr|F6S6P2|F6S6P2_HUMAN,tr|A0A0G2JL47|A0A0G2JL47_HUMAN,tr|A0A024RCR6|A0A024RCR6_HUMAN,tr|A0A0G2JK23|A0A0G2JK23_HUMAN" 9 1087.4903 1.8 60606 7571 2 1087.49222 544.7524 Large proline-rich protein BAG6 OS=Homo sapiens OX=9606 GN=BAG6 PE=1 SV=2 8.07 1821.1 - 456367 - - - 1.7802 - 1.689 0.415 - 259.2 1 2 0 0.0019 9 0 0 0 2.49E+07 1.38E+07 - - - 3.6219 0.9815 221125_WJC_METTL3_EV_vs_WT_F05.07572.07572.2 5.55E-06 20-Dec N.VSAAC[160.03]TSQELR.S "sp|Q96PK6|RBM14_HUMAN,tr|B8ZZ74|B8ZZ74_HUMAN,tr|F8WDX3|F8WDX3_HUMAN,tr|A0A0A0MSL8|A0A0A0MSL8_HUMAN,tr|A0A0A6YYI9|A0A0A6YYI9_HUMAN" 5 1220.5819 1.04 60607 7572 2 1220.584991 611.2982 RNA-binding protein 14 OS=Homo sapiens OX=9606 GN=RBM14 PE=1 SV=2 5.97 1821.2 - 303932 - - - 2.5029 - 2.482 0.515 - 818.6 1 1 0 0.0031 11 0 0 0 7.96E+06 7.65E+06 - - - 5.3031 0.9946 221125_WJC_METTL3_EV_vs_WT_F05.07578.07578.2 1.69 12-Jun R.DLDSLHR[166.11].F sp|Q8NBS9|TXND5_HUMAN 1 864.4329 0.18 60612 7578 2 864.431782 433.2237 Thioredoxin domain-containing protein 5 OS=Homo sapiens OX=9606 GN=TXNDC5 PE=1 SV=2 5.21 1822 - 329531 - - - -1.2933 - 1.103 0.261 - 153.1 1 2 0 -0.0011 7 0 0 0 3.40E+06 1.87E+07 - - - 1.279 0.9999 221125_WJC_METTL3_EV_vs_WT_F05.07581.07581.2 5.08E-06 18-Oct K.QNESTIVEPK[136.11].Q "sp|Q6KC79|NIPBL_HUMAN,tr|A0A590UJS4|A0A590UJS4_HUMAN" 2 1151.5914 2.23 60615 7581 2 1151.591817 576.803 Nipped-B-like protein OS=Homo sapiens OX=9606 GN=NIPBL PE=1 SV=2 4.53 1822.3 - 442565 - - - 0.3899 - 2.028 0.533 - 300.1 1 2 0 0.0004 10 0 0 0 2.68E+07 1.21E+07 - - - 4.9512 0.9974 221125_WJC_METTL3_EV_vs_WT_F05.07582.07582.2 0.00382 16-Sep K.TEDEVLTSK.G sp|Q9BQ61|TRIR_HUMAN 1 1020.4975 0.24 60616 7582 2 1020.500449 511.256 Telomerase RNA component interacting RNase OS=Homo sapiens OX=9606 GN=TRIR PE=1 SV=1 4.14 1822.4 - 377341 - - - 2.8702 - 1.497 0.352 - 268.3 1 2 0 0.0029 9 0 0 0 9.67E+06 4.08E+07 - - - 2.8072 0.9741 221125_WJC_METTL3_EV_vs_WT_F05.07583.07583.2 1.07 14-Jun R.RLAEALPK.Q "sp|P20290|BTF3_HUMAN,tr|A0A7I2V3T6|A0A7I2V3T6_HUMAN,tr|D6RDG3|D6RDG3_HUMAN,tr|A0A7I2V5Y3|A0A7I2V5Y3_HUMAN,tr|H0Y9Y1|H0Y9Y1_HUMAN,tr|A0A7I2YQL2|A0A7I2YQL2_HUMAN" 6 896.5444 0.99 60617 7583 2 896.545649 449.2795 Transcription factor BTF3 OS=Homo sapiens OX=9606 GN=BTF3 PE=1 SV=1 8.75 1822.5 - 366600 - - - 1.4478 - 1.368 0.063 - 165.9 2 2 0 0.0013 8 0 0 0 7.88E+06 7.92E+06 - - - 0.3165 0.9997 221125_WJC_METTL3_EV_vs_WT_F05.07584.07584.2 0.00229 24-Aug K.IISPGSSTPSSTR[166.11].S sp|Q5VT52|RPRD2_HUMAN 1 1298.6706 1.36 60618 7584 2 1298.670632 650.3426 Regulation of nuclear pre-mRNA domain-containing protein 2 OS=Homo sapiens OX=9606 GN=RPRD2 PE=1 SV=1 9.75 1822.7 - 121876 - - - 0.0524 - 1.821 0.41 - 198.5 1 2 0 0.0001 13 0 0 0 6.22E+06 4.57E+06 - - - 3.6076 0.9994 221125_WJC_METTL3_EV_vs_WT_F05.07588.07588.3 0.0114 Oct-36 K.SMQNHAAVFR[166.11].V "sp|P31040|SDHA_HUMAN,tr|A0A087X1I3|A0A087X1I3_HUMAN" 2 1169.5639 0.32 60620 7588 3 1169.565274 390.8619 "Succinate dehydrogenase [ubiquinone] flavoprotein subunit, mitochondrial OS=Homo sapiens OX=9606 GN=SDHA PE=1 SV=2" 9.49 1823.2 - 970603 - - - 1.1483 - 1.982 0.295 - 123.3 1 2 0 0.0013 10 0 0 0 1.29E+07 4.05E+07 - - - 3.8265 0.9995 221125_WJC_METTL3_EV_vs_WT_F05.07592.07592.2 2.73E-05 18-Oct R.SQAEDVATYK.V "sp|Q92830|KAT2A_HUMAN,tr|K7ERS6|K7ERS6_HUMAN" 2 1110.5193 0.74 60624 7592 2 1110.521611 556.2669 Histone acetyltransferase KAT2A OS=Homo sapiens OX=9606 GN=KAT2A PE=1 SV=3 4.37 1823.6 - 623315 - - - 2.0639 - 1.976 0.428 - 422.2 1 2 0 0.0023 10 0 0 0 7.66E+06 1.03E+07 - - - 4.1026 0.9993 221125_WJC_METTL3_EV_vs_WT_F05.07593.07593.2 0.0175 14-Oct R.AHSIQIMK[136.11].V "sp|Q02543|RL18A_HUMAN,tr|M0R3D6|M0R3D6_HUMAN,tr|M0R0P7|M0R0P7_HUMAN,tr|M0R117|M0R117_HUMAN,tr|M0R1A7|M0R1A7_HUMAN" 5 934.515 0.89 60625 7593 2 934.516242 468.2648 60S ribosomal protein L18a OS=Homo sapiens OX=9606 GN=RPL18A PE=1 SV=2 8.8 1823.7 - 388867 - - - 1.359 - 2.054 0.265 - 374.4 1 2 0 0.0013 8 0 0 0 1.98E+07 2.23E+07 - - - 3.1687 0.9998 221125_WJC_METTL3_EV_vs_WT_F05.07597.07597.2 9.00E-06 20-Dec R.NVTAIQGPGGK.W "sp|P50213|IDH3A_HUMAN,tr|H0YLI6|H0YLI6_HUMAN,tr|H0YM64|H0YM64_HUMAN,tr|H0YKD0|H0YKD0_HUMAN,tr|H0YL72|H0YL72_HUMAN,tr|H0YMU3|H0YMU3_HUMAN" 6 1040.5615 1.62 60627 7597 2 1040.561276 521.288 "Isocitrate dehydrogenase [NAD] subunit alpha, mitochondrial OS=Homo sapiens OX=9606 GN=IDH3A PE=1 SV=1" 8.75 1824.2 - 988946 - - - -0.1749 - 1.952 0.453 - 406.8 1 2 0 -0.0002 11 0 0 0 6.89E+07 4.26E+07 - - - 4.1962 0.9998 221125_WJC_METTL3_EV_vs_WT_F05.07598.07598.2 0.000248 16-Nov R.HGFEAASIK[136.11].E "sp|P35580|MYH10_HUMAN,tr|E7ERA5|E7ERA5_HUMAN" 2 966.5014 1.06 60628 7598 2 966.501719 484.258 Myosin-10 OS=Homo sapiens OX=9606 GN=MYH10 PE=1 SV=3 6.75 1824.3 - 579789 - - - 0.299 - 2.046 0.386 - 377 1 2 0 0.0003 9 0 0 0 2.69E+07 2.53E+07 - - - 3.963 0.9177 221125_WJC_METTL3_EV_vs_WT_F05.07604.07604.2 0.0967 14-Aug V.PVVHVDEK.G sp|Q8TEM1|PO210_HUMAN 1 921.492 1.58 60632 7604 2 921.49127 461.7533 Nuclear pore membrane glycoprotein 210 OS=Homo sapiens OX=9606 GN=NUP210 PE=1 SV=3 5.33 1825.1 - 271408 - - - -0.7727 - 1.442 0.266 - 244.8 1 1 0 -0.0007 8 0 0 0 6.75E+06 4.27E+06 - - - 2.1094 0.8588 221125_WJC_METTL3_EV_vs_WT_F05.07605.07605.3 0.733 Nov-36 K.QQLVASHLEK.L "sp|Q13561|DCTN2_HUMAN,tr|H0YI98|H0YI98_HUMAN,tr|A8K8J9|A8K8J9_HUMAN,tr|F8W1I6|F8W1I6_HUMAN,tr|A0A7I2V4H4|A0A7I2V4H4_HUMAN,tr|A0A7I2V390|A0A7I2V390_HUMAN,tr|A0A7I2V4Y9|A0A7I2V4Y9_HUMAN,tr|F8VW18|F8VW18_HUMAN" 8 1151.6299 6.94 60633 7605 3 1151.628881 384.8839 Dynactin subunit 2 OS=Homo sapiens OX=9606 GN=DCTN2 PE=1 SV=4 6.75 1825.2 - 690496 - - - -0.8605 - 1.681 0.016 - 170 1 2 0 -0.001 10 0 0 0 1.38E+07 1.98E+06 - - - 0.235 0.9996 221125_WJC_METTL3_EV_vs_WT_F05.07607.07607.2 4.83E-06 20-Dec R.QLEEAEEEASR.A "sp|Q7Z406|MYH14_HUMAN,tr|A1L2Z2|A1L2Z2_HUMAN" 2 1289.5735 1.19 60635 7607 2 1289.577248 645.794 Myosin-14 OS=Homo sapiens OX=9606 GN=MYH14 PE=1 SV=2 3.98 1825.4 - 278655 - - - 2.8761 - 2.348 0.515 - 790.1 1 2 0 0.0037 11 0 0 0 6.03E+06 5.05E+06 - - - 5.1527 0.9998 221125_WJC_METTL3_EV_vs_WT_F05.07608.07608.2 5.53E-05 22-Nov R.MATNAAAQNAIK.K sp|Q9Y490|TLN1_HUMAN 1 1202.6078 0.54 60636 7608 2 1202.607061 602.3112 Talin-1 OS=Homo sapiens OX=9606 GN=TLN1 PE=1 SV=3 8.5 1825.6 - 258606 - - - -0.5779 - 2.26 0.456 - 451.8 1 2 0 -0.0007 12 0 0 0 3.43E+06 6.30E+06 - - - 4.5542 0.9994 221125_WJC_METTL3_EV_vs_WT_F05.07611.07611.2 2.62E-05 16-Dec R.HGFEAASIK.E "sp|P35580|MYH10_HUMAN,tr|E7ERA5|E7ERA5_HUMAN" 2 958.4872 1.02 60637 7611 2 958.485497 480.2509 Myosin-10 OS=Homo sapiens OX=9606 GN=MYH10 PE=1 SV=3 6.75 1826 - 1.40E+06 - - - -1.8091 - 2.377 0.255 - 417.1 1 2 0 -0.0017 9 0 0 0 2.79E+07 2.73E+07 - - - 3.4288 0.9997 221125_WJC_METTL3_EV_vs_WT_F05.07612.07612.2 0.00107 14-Aug R.AHSIQIMK.V "sp|Q02543|RL18A_HUMAN,tr|M0R3D6|M0R3D6_HUMAN,tr|M0R0P7|M0R0P7_HUMAN,tr|M0R117|M0R117_HUMAN,tr|M0R1A7|M0R1A7_HUMAN" 5 926.5008 0.78 60638 7612 2 926.502089 464.2577 60S ribosomal protein L18a OS=Homo sapiens OX=9606 GN=RPL18A PE=1 SV=2 8.8 1826.1 - 941674 - - - 1.4215 - 1.964 0.439 - 256.2 1 2 0 0.0013 8 0 0 0 1.71E+07 2.18E+07 - - - 4.3188 0.9977 221125_WJC_METTL3_EV_vs_WT_F05.07613.07613.2 0.842 14-Sep K.SHLIQVER.E "sp|Q9Y6D9|MD1L1_HUMAN,tr|C9JJ38|C9JJ38_HUMAN" 2 980.5403 1.69 60639 7613 2 980.540223 491.2774 Mitotic spindle assembly checkpoint protein MAD1 OS=Homo sapiens OX=9606 GN=MAD1L1 PE=1 SV=2 6.47 1826.2 - 1.21E+06 - - - -0.1081 - 1.62 0.161 - 416.3 1 2 0 -0.0001 8 0 0 0 1.80E+07 1.06E+07 - - - 1.6851 0.9984 221125_WJC_METTL3_EV_vs_WT_F05.07614.07614.2 0.0609 20-Aug R.NVTAIQGPGGK[136.11].W "sp|P50213|IDH3A_HUMAN,tr|H0YLI6|H0YLI6_HUMAN,tr|H0YM64|H0YM64_HUMAN,tr|H0YKD0|H0YKD0_HUMAN,tr|H0YL72|H0YL72_HUMAN,tr|H0YMU3|H0YMU3_HUMAN" 6 1048.5757 1.41 60640 7614 2 1048.575903 525.2951 "Isocitrate dehydrogenase [NAD] subunit alpha, mitochondrial OS=Homo sapiens OX=9606 GN=IDH3A PE=1 SV=1" 8.75 1826.2 - 1.17E+06 - - - 0.2337 - 1.196 0.331 - 152.5 1 2 0 0.0002 11 0 0 0 2.54E+07 1.80E+07 - - - 1.9699 0.9997 221125_WJC_METTL3_EV_vs_WT_F05.07615.07615.3 0.00197 14/36 R.ALRQEFAASR.A "sp|Q9Y3D7|TIM16_HUMAN,tr|I3L3T0|I3L3T0_HUMAN,tr|A0A0A6YYL4|A0A0A6YYL4_HUMAN,tr|I3L1U7|I3L1U7_HUMAN,tr|I3L0X9|I3L0X9_HUMAN" 5 1147.6098 0.88 60641 7615 3 1147.611022 383.5439 Mitochondrial import inner membrane translocase subunit TIM16 OS=Homo sapiens OX=9606 GN=PAM16 PE=1 SV=2 9.64 1826.3 - 800627 - - - 1.0605 - 2.269 0.434 - 270.2 1 2 1 0.0012 10 0 0 0 9.24E+06 1.05E+07 - - - 5.7712 0.9996 221125_WJC_METTL3_EV_vs_WT_F05.07618.07618.2 0.000219 13/20 R.QLEEAEEEAQR[166.11].A sp|P35579|MYH9_HUMAN 1 1340.6084 1.15 60644 7618 2 1340.611407 671.3115 Myosin-9 OS=Homo sapiens OX=9606 GN=MYH9 PE=1 SV=4 3.98 1826.7 - 267107 - - - 2.2743 - 2.366 0.453 - 911.4 1 2 0 0.003 11 0 0 0 1.02E+08 8.85E+07 - - - 4.7157 0.9755 221125_WJC_METTL3_EV_vs_WT_F05.07624.07624.2 0.478 12-Jul R.R[166.11]QLLLQK[136.11].L "sp|Q9UJV9|DDX41_HUMAN,tr|A0A499FJW5|A0A499FJW5_HUMAN,tr|D6RGI7|D6RGI7_HUMAN" 3 915.5985 0.97 60648 7624 2 915.599023 458.8065 Probable ATP-dependent RNA helicase DDX41 OS=Homo sapiens OX=9606 GN=DDX41 PE=1 SV=2 11 1827.5 - 949851 - - - 0.6193 - 1.314 0.027 - 166.2 1 2 0 0.0006 7 0 0 0 1.12E+07 1.16E+07 - - - 0.1055 0.9999 221125_WJC_METTL3_EV_vs_WT_F05.07625.07625.2 0.000124 13/20 R.QLEEAEEEAQR.A sp|P35579|MYH9_HUMAN 1 1330.6001 1.15 60649 7625 2 1330.600404 666.3073 Myosin-9 OS=Homo sapiens OX=9606 GN=MYH9 PE=1 SV=4 3.98 1827.6 - 789543 - - - 0.2375 - 2.473 0.523 - 993.3 1 2 0 0.0003 11 0 0 0 1.02E+08 8.85E+07 - - - 5.3532 0.9997 221125_WJC_METTL3_EV_vs_WT_F05.07637.07637.2 0.00443 18-Oct R.IADGYEQAAR[166.11].V "sp|P48643|TCPE_HUMAN,tr|E9PCA1|E9PCA1_HUMAN,tr|B7ZAR1|B7ZAR1_HUMAN,tr|E7ENZ3|E7ENZ3_HUMAN" 4 1102.5283 0.65 60659 7637 2 1102.527728 552.2714 T-complex protein 1 subunit epsilon OS=Homo sapiens OX=9606 GN=CCT5 PE=1 SV=1 4.37 1829 - 1.10E+06 - - - -0.4798 - 1.953 0.358 - 308.1 1 2 0 -0.0005 10 0 0 0 3.25E+07 5.02E+07 - - - 3.5534 0.9827 221125_WJC_METTL3_EV_vs_WT_F05.07638.07638.2 2.47 12-Sep R.RQLLLQK.L "sp|Q9UJV9|DDX41_HUMAN,tr|A0A499FJW5|A0A499FJW5_HUMAN,tr|D6RGI7|D6RGI7_HUMAN" 3 897.576 0.97 60660 7638 2 897.576133 449.7953 Probable ATP-dependent RNA helicase DDX41 OS=Homo sapiens OX=9606 GN=DDX41 PE=1 SV=2 11 1829.1 - 731445 - - - 0.1638 - 1.365 0.032 - 369.9 1 2 0 0.0001 7 0 0 0 1.12E+07 1.16E+07 - - - 0.2632 0.9999 221125_WJC_METTL3_EV_vs_WT_F05.07639.07639.2 0.000144 18-Dec R.IADGYEQAAR.V "sp|P48643|TCPE_HUMAN,tr|E9PCA1|E9PCA1_HUMAN,tr|B7ZAR1|B7ZAR1_HUMAN,tr|E7ENZ3|E7ENZ3_HUMAN" 4 1092.52 0.65 60661 7639 2 1092.519916 547.2673 T-complex protein 1 subunit epsilon OS=Homo sapiens OX=9606 GN=CCT5 PE=1 SV=1 4.37 1829.2 - 670185 - - - -0.065 - 2.546 0.439 - 435.3 1 2 0 -0.0001 10 0 0 0 3.23E+07 5.00E+07 - - - 4.892 0.9969 221125_WJC_METTL3_EV_vs_WT_F05.07641.07641.3 0.00914 Sep-36 K.LLEQYK[136.11]EESK[136.11].K "sp|Q00839|HNRPU_HUMAN,tr|A0A1W2PQL0|A0A1W2PQL0_HUMAN,tr|A0A1W2PPL4|A0A1W2PPL4_HUMAN,tr|Q5RI18|Q5RI18_HUMAN,tr|A0A1W2PP35|A0A1W2PP35_HUMAN,tr|A0A1W2PPS1|A0A1W2PPS1_HUMAN,tr|A0A1W2PPH7|A0A1W2PPH7_HUMAN,tr|A0A1W2PQD4|A0A1W2PQD4_HUMAN,tr|A0A1W2PP34|A0A1W2PP34_HUMAN,tr|A0A1X7SBS1|A0A1X7SBS1_HUMAN" 10 1281.6787 1.02 60663 7641 3 1281.679123 428.2335 Heterogeneous nuclear ribonucleoprotein U OS=Homo sapiens OX=9606 GN=HNRNPU PE=1 SV=6 4.79 1829.5 - 431998 - - - 0.3043 - 2.056 0.265 - 134.8 1 2 1 0.0004 10 0 0 0 4.17E+08 4.07E+08 - - - 3.5993 0.9945 221125_WJC_METTL3_EV_vs_WT_F05.07642.07642.2 0.296 14-Jun K.DSEGVDIK[136.11].L "sp|O43491|E41L2_HUMAN,tr|A0A2R8Y5B3|A0A2R8Y5B3_HUMAN,tr|E9PII3|E9PII3_HUMAN,tr|E9PHY5|E9PHY5_HUMAN,tr|E9PK52|E9PK52_HUMAN" 5 869.4222 1.1 60664 7642 2 869.421102 435.7184 Band 4.1-like protein 2 OS=Homo sapiens OX=9606 GN=EPB41L2 PE=1 SV=1 4.03 1829.6 - 236715 - - - -1.2365 - 1.407 0.158 - 136.8 1 2 0 -0.0011 8 0 0 0 4.91E+06 4.45E+06 - - - 1.2375 0.9982 221125_WJC_METTL3_EV_vs_WT_F05.07646.07646.2 0.0483 16-Jun K.STMQELNSR.L sp|P35527|K1C9_HUMAN 1 1064.4921 33055.15 60666 7646 2 1064.490351 533.2533 "Keratin, type I cytoskeletal 9 OS=Homo sapiens OX=9606 GN=KRT9 PE=1 SV=3" 5.72 1830.1 - 1.29E+06 - - - -1.6036 - 1.558 0.267 - 141.4 1 2 0 -0.0017 9 0 0 0 9.57E+09 2.89E+05 - - - 2.2953 0.9986 221125_WJC_METTL3_EV_vs_WT_F05.07647.07647.3 0.00223 Nov-36 K.LLEQYKEESK.K "sp|Q00839|HNRPU_HUMAN,tr|A0A1W2PQL0|A0A1W2PQL0_HUMAN,tr|A0A1W2PPL4|A0A1W2PPL4_HUMAN,tr|Q5RI18|Q5RI18_HUMAN,tr|A0A1W2PP35|A0A1W2PP35_HUMAN,tr|A0A1W2PPS1|A0A1W2PPS1_HUMAN,tr|A0A1W2PPH7|A0A1W2PPH7_HUMAN,tr|A0A1W2PQD4|A0A1W2PQD4_HUMAN,tr|A0A1W2PP34|A0A1W2PP34_HUMAN,tr|A0A1X7SBS1|A0A1X7SBS1_HUMAN" 10 1265.6503 1.02 60667 7647 3 1265.649581 422.8907 Heterogeneous nuclear ribonucleoprotein U OS=Homo sapiens OX=9606 GN=HNRNPU PE=1 SV=6 4.79 1830.2 - 1.16E+06 - - - -0.5942 - 2.212 0.302 - 209.2 1 2 1 -0.0008 10 0 0 0 4.17E+08 4.07E+08 - - - 4.2253 0.9948 221125_WJC_METTL3_EV_vs_WT_F05.07648.07648.3 0.0134 Nov-36 K.QMQVLHPAAR[166.11].M sp|P50991|TCPD_HUMAN 1 1159.616 0.31 60668 7648 3 1159.61427 387.5459 T-complex protein 1 subunit delta OS=Homo sapiens OX=9606 GN=CCT4 PE=1 SV=4 9.76 1830.3 - 977762 - - - -1.4634 - 1.96 0.166 - 188.9 1 2 0 -0.0017 10 0 0 0 4.06E+08 1.30E+09 - - - 2.3556 0.9997 221125_WJC_METTL3_EV_vs_WT_F05.07649.07649.2 0.000469 20-Oct R.STAPAVAYDSK.Q sp|Q96KR1|ZFR_HUMAN 1 1108.5401 1.37 60669 7649 2 1108.539172 555.2773 Zinc finger RNA-binding protein OS=Homo sapiens OX=9606 GN=ZFR PE=1 SV=2 5.55 1830.4 - 907125 - - - -0.7956 - 1.835 0.395 - 346.4 1 2 0 -0.0009 11 0 0 0 1.37E+08 1.00E+08 - - - 3.6004 0.9982 221125_WJC_METTL3_EV_vs_WT_F05.07650.07650.2 0.0783 18-Sep K.YIQAEPPTNK.S "sp|Q8TAQ2|SMRC2_HUMAN,tr|F8VXC8|F8VXC8_HUMAN,tr|F8VZW6|F8VZW6_HUMAN" 3 1159.5873 0.83 60670 7650 2 1159.586716 580.8009 SWI\SNF complex subunit SMARCC2 OS=Homo sapiens OX=9606 GN=SMARCC2 PE=1 SV=1 6 1830.5 - 420112 - - - -0.5373 - 1.376 0.264 - 228 1 2 0 -0.0006 10 0 0 0 8.38E+06 1.01E+07 - - - 1.8816 0.9998 221125_WJC_METTL3_EV_vs_WT_F05.07651.07651.2 0.000133 26-Nov R.LASAQEVAGSTSAK.T "sp|Q8IYL3|CA174_HUMAN,tr|A0A7P0TAC3|A0A7P0TAC3_HUMAN,tr|A0A7P0T887|A0A7P0T887_HUMAN,tr|A0A7P0TAV4|A0A7P0TAV4_HUMAN,tr|A0A7P0T8M5|A0A7P0T8M5_HUMAN,tr|A0A7P0T8I3|A0A7P0T8I3_HUMAN" 6 1318.6729 0.87 60671 7651 2 1318.67136 660.3437 UPF0688 protein C1orf174 OS=Homo sapiens OX=9606 GN=C1orf174 PE=1 SV=2 6 1830.6 - 390383 - - - -1.1367 - 2.388 0.452 - 400.8 1 2 0 -0.0015 14 0 0 0 5.16E+06 5.96E+06 - - - 4.5634 0.9859 221125_WJC_METTL3_EV_vs_WT_F05.07654.07654.2 0.131 18-Jul K.LLEQYK[136.11]EESK[136.11].K "sp|Q00839|HNRPU_HUMAN,tr|A0A1W2PQL0|A0A1W2PQL0_HUMAN,tr|A0A1W2PPL4|A0A1W2PPL4_HUMAN,tr|Q5RI18|Q5RI18_HUMAN,tr|A0A1W2PP35|A0A1W2PP35_HUMAN,tr|A0A1W2PPS1|A0A1W2PPS1_HUMAN,tr|A0A1W2PPH7|A0A1W2PPH7_HUMAN,tr|A0A1W2PQD4|A0A1W2PQD4_HUMAN,tr|A0A1W2PP34|A0A1W2PP34_HUMAN,tr|A0A1X7SBS1|A0A1X7SBS1_HUMAN" 10 1281.6787 1.14 60674 7654 2 1281.676635 641.8466 Heterogeneous nuclear ribonucleoprotein U OS=Homo sapiens OX=9606 GN=HNRNPU PE=1 SV=6 4.79 1831 - 134585 - - - -1.6369 - 1.73 0.278 - 162.7 1 2 1 -0.0021 10 0 0 0 6.33E+07 5.55E+07 - - - 2.6236 0.9948 221125_WJC_METTL3_EV_vs_WT_F05.07660.07660.2 5.62E-07 20-Nov L.FAQGNYSEAAK[136.11].V "sp|Q00610|CLH1_HUMAN,tr|A0A087WVQ6|A0A087WVQ6_HUMAN" 2 1192.5604 1.03 60678 7660 2 1192.560354 597.2875 Clathrin heavy chain 1 OS=Homo sapiens OX=9606 GN=CLTC PE=1 SV=5 6 1831.8 - 576843 - - - -0.0402 - 2.168 0.599 - 291.7 1 1 0 0 11 0 0 0 1.12E+07 1.09E+07 - - - 5.5585 0.9991 221125_WJC_METTL3_EV_vs_WT_F05.07664.07664.2 9.01E-06 18-Oct R.TENGGQVMYR.V "sp|P22415|USF1_HUMAN,tr|B1AQP1|B1AQP1_HUMAN,tr|E9PME6|E9PME6_HUMAN" 3 1153.5186 2.25 60682 7664 2 1153.52208 577.7666 Upstream stimulatory factor 1 OS=Homo sapiens OX=9606 GN=USF1 PE=1 SV=1 5.66 1832.3 - 186053 - - - 3.0108 - 1.922 0.438 - 326.4 1 2 0 0.0035 10 0 0 0 3.56E+06 1.58E+06 - - - 4.0987 0.8509 221125_WJC_METTL3_EV_vs_WT_F05.07667.07667.3 0.0895 Aug-36 R.VDHVMDSVAR[166.11].K sp|Q8TAT5|NEIL3_HUMAN 1 1137.5476 0.001 60685 7667 3 1138.546715 380.1898 Endonuclease 8-like 3 OS=Homo sapiens OX=9606 GN=NEIL3 PE=1 SV=3 5.21 1832.7 - 115550 - - - 878.2955 - 1.672 0.322 - 80.4 1 2 0 0.9991 10 0 0 0 0.00E+00 1.83E+06 - - - 3.3544 0.9996 221125_WJC_METTL3_EV_vs_WT_F05.07669.07669.2 0.0136 16-Aug R.GQVPMQDPR.A "sp|P33240|CSTF2_HUMAN,tr|E9PID8|E9PID8_HUMAN" 2 1026.4917 0.72 60686 7669 2 1026.492687 514.2531 Cleavage stimulation factor subunit 2 OS=Homo sapiens OX=9606 GN=CSTF2 PE=1 SV=1 5.84 1832.9 - 1.56E+06 - - - 0.9966 - 1.49 0.446 - 232.7 1 2 0 0.001 9 0 0 0 4.23E+07 5.91E+07 - - - 3.4885 0.9986 221125_WJC_METTL3_EV_vs_WT_F05.07675.07675.2 0.000112 18-Dec K.LLEQYKEESK.K "sp|Q00839|HNRPU_HUMAN,tr|A0A1W2PQL0|A0A1W2PQL0_HUMAN,tr|A0A1W2PPL4|A0A1W2PPL4_HUMAN,tr|Q5RI18|Q5RI18_HUMAN,tr|A0A1W2PP35|A0A1W2PP35_HUMAN,tr|A0A1W2PPS1|A0A1W2PPS1_HUMAN,tr|A0A1W2PPH7|A0A1W2PPH7_HUMAN,tr|A0A1W2PQD4|A0A1W2PQD4_HUMAN,tr|A0A1W2PP34|A0A1W2PP34_HUMAN,tr|A0A1X7SBS1|A0A1X7SBS1_HUMAN" 10 1265.6503 1.14 60691 7675 2 1265.649008 633.8324 Heterogeneous nuclear ribonucleoprotein U OS=Homo sapiens OX=9606 GN=HNRNPU PE=1 SV=6 4.79 1833.4 - 1.13E+06 - - - -1.0469 - 2.449 0.492 - 549.8 1 2 1 -0.0013 10 0 0 0 6.33E+07 5.55E+07 - - - 5.1746 0.9831 221125_WJC_METTL3_EV_vs_WT_F05.07676.07676.2 0.000545 20-Oct L.FAQGNYSEAAK.V "sp|Q00610|CLH1_HUMAN,tr|A0A087WVQ6|A0A087WVQ6_HUMAN" 2 1184.5462 1.05 60692 7676 2 1184.54496 593.2804 Clathrin heavy chain 1 OS=Homo sapiens OX=9606 GN=CLTC PE=1 SV=5 6 1833.5 - 928504 - - - -1.0485 - 1.57 0.49 - 250.4 1 1 0 -0.0012 11 0 0 0 1.17E+07 1.12E+07 - - - 3.88 0.8662 221125_WJC_METTL3_EV_vs_WT_F05.07680.07680.2 0.00042 16-Nov L.LEQYKEESK.K "sp|Q00839|HNRPU_HUMAN,tr|A0A1W2PQL0|A0A1W2PQL0_HUMAN,tr|A0A1W2PPL4|A0A1W2PPL4_HUMAN,tr|Q5RI18|Q5RI18_HUMAN,tr|A0A1W2PP35|A0A1W2PP35_HUMAN,tr|A0A1W2PPS1|A0A1W2PPS1_HUMAN,tr|A0A1W2PPH7|A0A1W2PPH7_HUMAN,tr|A0A1W2PQD4|A0A1W2PQD4_HUMAN,tr|A0A1W2PP34|A0A1W2PP34_HUMAN,tr|A0A1X7SBS1|A0A1X7SBS1_HUMAN" 10 1152.5663 0.8 60696 7680 2 1152.56524 577.2904 Heterogeneous nuclear ribonucleoprotein U OS=Homo sapiens OX=9606 GN=HNRNPU PE=1 SV=6 4.79 1834 - 498777 - - - -0.8928 - 1.945 0.422 - 395.2 1 1 1 -0.001 9 0 0 0 1.80E+07 2.23E+07 - - - 4.0822 0.9997 221125_WJC_METTL3_EV_vs_WT_F05.07681.07681.2 0.000309 20-Sep K.LTVAENEAETK[136.11].L sp|P07814|SYEP_HUMAN 1 1211.6125 4.56 60697 7681 2 1211.61311 606.8135 Bifunctional glutamate\proline--tRNA ligase OS=Homo sapiens OX=9606 GN=EPRS1 PE=1 SV=5 4.25 1834.1 - 308790 - - - 0.5059 - 1.802 0.395 - 222.5 1 2 0 0.0006 11 0 0 0 1.83E+07 4.01E+06 - - - 3.5514 0.8562 221125_WJC_METTL3_EV_vs_WT_F05.07683.07683.2 0.0667 20-Jun K.IISNASC[160.03]TTNC[160.03].L "sp|P04406|G3P_HUMAN,tr|E7EUT5|E7EUT5_HUMAN" 2 1239.5224 - 60698 7683 2 1239.52118 620.7685 Glyceraldehyde-3-phosphate dehydrogenase OS=Homo sapiens OX=9606 GN=GAPDH PE=1 SV=3 5.51 1834.3 - 1.12E+06 - - - -0.9617 - 1.253 0.272 - 103.6 1 1 0 -0.0012 11 0 0 0 - - - - - 1.6598 0.9989 221125_WJC_METTL3_EV_vs_WT_F05.07689.07689.2 0.00827 18-Oct R.NPGPSGPQLR.D "sp|Q86Y82|STX12_HUMAN,tr|B1AJQ6|B1AJQ6_HUMAN" 2 1021.5305 2.41 60703 7689 2 1021.528228 511.7725 Syntaxin-12 OS=Homo sapiens OX=9606 GN=STX12 PE=1 SV=1 9.75 1834.9 - 795583 - - - -2.2163 - 1.661 0.36 - 379.7 1 2 0 -0.0023 10 0 0 0 4.22E+07 1.75E+07 - - - 3.1156 0.9998 221125_WJC_METTL3_EV_vs_WT_F05.07691.07691.2 1.82E-06 18-Dec K.QMQVLHPAAR[166.11].M sp|P50991|TCPD_HUMAN 1 1159.616 0.33 60705 7691 2 1159.61536 580.8153 T-complex protein 1 subunit delta OS=Homo sapiens OX=9606 GN=CCT4 PE=1 SV=4 9.76 1835.1 - 504098 - - - -0.5234 - 1.878 0.504 - 580.8 1 2 0 -0.0006 10 0 0 0 3.45E+07 1.06E+08 - - - 4.5225 0.9933 221125_WJC_METTL3_EV_vs_WT_F05.07697.07697.2 0.513 16-Sep R.LEC[160.03]VEPNC[160.03]R[166.11].S "sp|P83881|RL36A_HUMAN,sp|Q969Q0|RL36L_HUMAN,tr|H0Y5B4|H0Y5B4_HUMAN,tr|J3KQN4|J3KQN4_HUMAN,tr|H7BZ11|H7BZ11_HUMAN" 5 1185.5146 0.9 60709 7697 2 1185.508333 593.7646 60S ribosomal protein L36a OS=Homo sapiens OX=9606 GN=RPL36A PE=1 SV=2 4.53 1835.8 - 2.03E+06 - - - -5.2846 - 2.021 0.346 - 376.4 1 2 0 -0.0063 9 0 0 0 6.29E+07 7.01E+07 - - - 3.6301 0.9996 221125_WJC_METTL3_EV_vs_WT_F05.07700.07700.2 2.63E-05 16-Oct R.LEC[160.03]VEPNC[160.03]R.S "sp|P83881|RL36A_HUMAN,sp|Q969Q0|RL36L_HUMAN,tr|H0Y5B4|H0Y5B4_HUMAN,tr|J3KQN4|J3KQN4_HUMAN,tr|H7BZ11|H7BZ11_HUMAN" 5 1175.5063 0.9 60710 7700 2 1175.503783 588.7604 60S ribosomal protein L36a OS=Homo sapiens OX=9606 GN=RPL36A PE=1 SV=2 4.53 1836.2 - 1.82E+06 - - - -2.165 - 2.052 0.418 - 486.7 1 2 0 -0.0025 9 0 0 0 6.29E+07 7.01E+07 - - - 4.2071 0.9873 221125_WJC_METTL3_EV_vs_WT_F05.07702.07702.2 0.309 16-Jul K.EGIPPDQQR[166.11].L "sp|P62979|RS27A_HUMAN,sp|P0CG48|UBC_HUMAN,sp|P0CG48|UBC_HUMAN,sp|P0CG48|UBC_HUMAN,sp|P0CG48|UBC_HUMAN,sp|P0CG48|UBC_HUMAN,sp|P0CG48|UBC_HUMAN,sp|P0CG48|UBC_HUMAN,sp|P0CG48|UBC_HUMAN,sp|P0CG48|UBC_HUMAN,sp|P0CG47|UBB_HUMAN,sp|P0CG47|UBB_HUMAN,sp|P0CG47|UBB_HUMAN,sp|P62987|RL40_HUMAN,tr|F5H388|F5H388_HUMAN,tr|F5H388|F5H388_HUMAN,tr|F5GYU3|F5GYU3_HUMAN,tr|F5GYU3|F5GYU3_HUMAN,tr|B4DV12|B4DV12_HUMAN,tr|B4DV12|B4DV12_HUMAN,tr|J3QSA3|J3QSA3_HUMAN,tr|Q5PY61|Q5PY61_HUMAN,tr|Q5PY61|Q5PY61_HUMAN,tr|Q5PY61|Q5PY61_HUMAN,tr|F5H2Z3|F5H2Z3_HUMAN,tr|F5H2Z3|F5H2Z3_HUMAN,tr|M0R2S1|M0R2S1_HUMAN,tr|J3QS39|J3QS39_HUMAN,tr|J3QTR3|J3QTR3_HUMAN,tr|Q96C32|Q96C32_HUMAN,tr|Q96C32|Q96C32_HUMAN,tr|Q96C32|Q96C32_HUMAN,tr|Q96C32|Q96C32_HUMAN,tr|M0R1V7|M0R1V7_HUMAN,tr|F5H747|F5H747_HUMAN,tr|F5H747|F5H747_HUMAN,tr|F5GXK7|F5GXK7_HUMAN,tr|F5GXK7|F5GXK7_HUMAN,tr|M0R1M6|M0R1M6_HUMAN,tr|F5H6Q2|F5H6Q2_HUMAN,tr|F5H6Q2|F5H6Q2_HUMAN,tr|F5GZ39|F5GZ39_HUMAN,tr|J3QKN0|J3QKN0_HUMAN,tr|J3QKN0|J3QKN0_HUMAN,tr|J3QKN0|J3QKN0_HUMAN,tr|F5H265|F5H265_HUMAN,tr|F5H265|F5H265_HUMAN,tr|A0A2R8Y422|A0A2R8Y422_HUMAN" 48 1048.5177 0.81 60712 7702 2 1048.517773 525.2661 Ubiquitin-40S ribosomal protein S27a OS=Homo sapiens OX=9606 GN=RPS27A PE=1 SV=2 4.37 1836.3 - 997114 - - - 0.0763 - 1.262 0.101 - 178.2 1 2 0 0.0001 9 0 0 0 3.80E+07 4.70E+07 - - - 0.4602 0.9999 221125_WJC_METTL3_EV_vs_WT_F05.07706.07706.3 7.07E-05 14/40 R.LVSGLEAK[136.11]PDR[166.11].S sp|O15119|TBX3_HUMAN 1 1201.6786 0.93 60714 7706 3 1201.675423 401.5668 T-box transcription factor TBX3 OS=Homo sapiens OX=9606 GN=TBX3 PE=1 SV=4 6.07 1836.8 - 3.00E+06 - - - -2.608 - 2.591 0.463 - 234.8 1 2 0 -0.0031 11 0 0 0 2.09E+08 2.26E+08 - - - 6.4057 0.8981 221125_WJC_METTL3_EV_vs_WT_F05.07708.07708.2 0.649 16-Jul K.ISLGQQSGR[166.11].V "sp|O75970|MPDZ_HUMAN,tr|H0YGQ3|H0YGQ3_HUMAN,tr|F5H1U9|F5H1U9_HUMAN" 3 954.5122 2.88 60716 7708 2 954.507907 478.2634 Multiple PDZ domain protein OS=Homo sapiens OX=9606 GN=MPDZ PE=1 SV=2 9.75 1837.1 - 957322 - - - -4.5112 - 1.346 0.151 - 109.3 4 2 0 -0.0043 9 0 0 0 5.58E+07 1.94E+07 - - - 0.7456 0.9887 221125_WJC_METTL3_EV_vs_WT_F05.07709.07709.2 0.0259 20-Aug R.LVSDGNINSDR[166.11].L "sp|Q01082|SPTB2_HUMAN,tr|A0A087WUZ3|A0A087WUZ3_HUMAN" 2 1198.5817 1.59 60717 7709 2 1198.576084 600.2982 "Spectrin beta chain, non-erythrocytic 1 OS=Homo sapiens OX=9606 GN=SPTBN1 PE=1 SV=2" 4.21 1837.2 - 639392 - - - -4.7264 - 1.413 0.364 - 68.8 1 2 0 -0.0057 11 0 0 0 7.71E+07 4.83E+07 - - - 2.663 0.999 221125_WJC_METTL3_EV_vs_WT_F05.07710.07710.2 0.0141 20-Oct K.IANPVEGSSGR[166.11].Q sp|Q15365|PCBP1_HUMAN 1 1095.5548 0.92 60718 7710 2 1095.552654 548.7847 Poly(rC)-binding protein 1 OS=Homo sapiens OX=9606 GN=PCBP1 PE=1 SV=2 6 1837.3 - 429140 - - - -1.9643 - 2.147 0.267 - 289.5 1 2 0 -0.0022 11 0 0 0 1.42E+08 1.54E+08 - - - 3.0794 0.9812 221125_WJC_METTL3_EV_vs_WT_F05.07714.07714.3 0.0582 Sep-36 K.YALTGDEVK[136.11]K[136.11].L "sp|P62701|RS4X_HUMAN,sp|P22090|RS4Y1_HUMAN,sp|Q8TD47|RS4Y2_HUMAN,tr|C9JEH7|C9JEH7_HUMAN" 4 1138.6205 0.001 60720 7714 3 1138.6161 380.5474 "40S ribosomal protein S4, X isoform OS=Homo sapiens OX=9606 GN=RPS4X PE=1 SV=2" 6.07 1837.8 - 1.33E+06 - - - -3.8555 - 1.69 0.229 - 77.2 1 2 0 -0.0044 10 0 0 0 0.00E+00 2.64E+08 - - - 2.6243 0.9996 221125_WJC_METTL3_EV_vs_WT_F05.07715.07715.2 0.00118 18-Sep R.DYDAMGSQTK[136.11].F "sp|Q9Y230|RUVB2_HUMAN,tr|M0R0Y3|M0R0Y3_HUMAN" 2 1122.4743 0.93 60721 7715 2 1122.472759 562.2444 RuvB-like 2 OS=Homo sapiens OX=9606 GN=RUVBL2 PE=1 SV=3 4.21 1837.9 - 574622 - - - -1.3631 - 1.475 0.475 - 230 1 2 0 -0.0015 10 0 0 0 1.04E+07 1.12E+07 - - - 3.6337 0.9946 221125_WJC_METTL3_EV_vs_WT_F05.07720.07720.2 1.67 14-Sep K.SEITELRR.N "sp|P13645|K1C10_HUMAN,tr|A0A1B0GVI3|A0A1B0GVI3_HUMAN" 2 1002.5458 999 60724 7720 2 1002.543447 502.2802 "Keratin, type I cytoskeletal 10 OS=Homo sapiens OX=9606 GN=KRT10 PE=1 SV=6" 5.86 1838.5 - 2.38E+08 - - - -2.355 - 1.581 0.189 - 202.9 1 2 0 -0.0024 8 0 0 0 4.33E+09 0.00E+00 - - - 1.8177 0.8187 221125_WJC_METTL3_EV_vs_WT_F05.07721.07721.2 0.0195 12-Jul T.MQELNSR.L sp|P35527|K1C9_HUMAN 1 876.4124 13.27 60725 7721 2 876.410005 439.2135 "Keratin, type I cytoskeletal 9 OS=Homo sapiens OX=9606 GN=KRT9 PE=1 SV=3" 5.75 1838.6 - 2.20E+06 - - - -2.6768 - 1.59 0.265 - 160.5 2 1 0 -0.0023 7 0 0 0 3.36E+07 2.53E+06 - - - 2.3324 0.9699 221125_WJC_METTL3_EV_vs_WT_F05.07722.07722.2 0.197 16-Jul K.EGIPPDQQR.L "sp|P62979|RS27A_HUMAN,sp|P0CG48|UBC_HUMAN,sp|P0CG48|UBC_HUMAN,sp|P0CG48|UBC_HUMAN,sp|P0CG48|UBC_HUMAN,sp|P0CG48|UBC_HUMAN,sp|P0CG48|UBC_HUMAN,sp|P0CG48|UBC_HUMAN,sp|P0CG48|UBC_HUMAN,sp|P0CG48|UBC_HUMAN,sp|P0CG47|UBB_HUMAN,sp|P0CG47|UBB_HUMAN,sp|P0CG47|UBB_HUMAN,sp|P62987|RL40_HUMAN,tr|F5H388|F5H388_HUMAN,tr|F5H388|F5H388_HUMAN,tr|F5GYU3|F5GYU3_HUMAN,tr|F5GYU3|F5GYU3_HUMAN,tr|B4DV12|B4DV12_HUMAN,tr|B4DV12|B4DV12_HUMAN,tr|J3QSA3|J3QSA3_HUMAN,tr|Q5PY61|Q5PY61_HUMAN,tr|Q5PY61|Q5PY61_HUMAN,tr|Q5PY61|Q5PY61_HUMAN,tr|F5H2Z3|F5H2Z3_HUMAN,tr|F5H2Z3|F5H2Z3_HUMAN,tr|M0R2S1|M0R2S1_HUMAN,tr|J3QS39|J3QS39_HUMAN,tr|J3QTR3|J3QTR3_HUMAN,tr|Q96C32|Q96C32_HUMAN,tr|Q96C32|Q96C32_HUMAN,tr|Q96C32|Q96C32_HUMAN,tr|Q96C32|Q96C32_HUMAN,tr|M0R1V7|M0R1V7_HUMAN,tr|F5H747|F5H747_HUMAN,tr|F5H747|F5H747_HUMAN,tr|F5GXK7|F5GXK7_HUMAN,tr|F5GXK7|F5GXK7_HUMAN,tr|M0R1M6|M0R1M6_HUMAN,tr|F5H6Q2|F5H6Q2_HUMAN,tr|F5H6Q2|F5H6Q2_HUMAN,tr|F5GZ39|F5GZ39_HUMAN,tr|J3QKN0|J3QKN0_HUMAN,tr|J3QKN0|J3QKN0_HUMAN,tr|J3QKN0|J3QKN0_HUMAN,tr|F5H265|F5H265_HUMAN,tr|F5H265|F5H265_HUMAN,tr|A0A2R8Y422|A0A2R8Y422_HUMAN" 48 1038.5094 0.81 60726 7722 2 1038.506514 520.262 Ubiquitin-40S ribosomal protein S27a OS=Homo sapiens OX=9606 GN=RPS27A PE=1 SV=2 4.37 1838.8 - 1.09E+06 - - - -2.8011 - 1.204 0.162 - 167.3 1 2 0 -0.0029 9 0 0 0 3.93E+07 4.87E+07 - - - 0.7737 0.9998 221125_WJC_METTL3_EV_vs_WT_F05.07723.07723.2 0.00385 18-Oct K.YALTGDEVK[136.11]K[136.11].L "sp|P62701|RS4X_HUMAN,sp|P22090|RS4Y1_HUMAN,sp|Q8TD47|RS4Y2_HUMAN,tr|C9JEH7|C9JEH7_HUMAN" 4 1138.6205 0.86 60727 7723 2 1138.619818 570.3175 "40S ribosomal protein S4, X isoform OS=Homo sapiens OX=9606 GN=RPS4X PE=1 SV=2" 6.07 1838.9 - 591700 - - - -0.5902 - 1.892 0.419 - 321.6 1 2 0 -0.0007 10 0 0 0 5.05E+07 5.89E+07 - - - 3.9154 1 221125_WJC_METTL3_EV_vs_WT_F05.07728.07728.2 3.06E-09 15/28 R.GDVTAEEAAGASPAK[136.11].A sp|P49006|MRP_HUMAN 1 1380.6612 0.84 60729 7728 2 1380.657327 691.3379 MARCKS-related protein OS=Homo sapiens OX=9606 GN=MARCKSL1 PE=1 SV=2 4.14 1839.5 - 352672 - - - -2.8327 - 2.887 0.646 - 851.2 1 2 0 -0.0039 15 0 0 0 1.84E+07 2.20E+07 - - - 6.4177 0.9997 221125_WJC_METTL3_EV_vs_WT_F05.07731.07731.2 1.52E-06 13/18 K.QMQVLHPAAR.M sp|P50991|TCPD_HUMAN 1 1149.6077 0.32 60731 7731 2 1149.604593 575.8111 T-complex protein 1 subunit delta OS=Homo sapiens OX=9606 GN=CCT4 PE=1 SV=4 9.76 1839.8 - 1.11E+06 - - - -2.7001 - 2.285 0.541 - 815.9 1 2 0 -0.0031 10 0 0 0 3.45E+07 1.06E+08 - - - 5.3425 0.9996 221125_WJC_METTL3_EV_vs_WT_F05.07742.07742.2 0.00221 16-Sep K.GPSSVEDIK.A "sp|P06748|NPM_HUMAN,tr|E5RI98|E5RI98_HUMAN,tr|A0A7I2YQC0|A0A7I2YQC0_HUMAN,tr|A0A7I2V5J8|A0A7I2V5J8_HUMAN,tr|A0A7I2V5S2|A0A7I2V5S2_HUMAN" 5 930.4658 0.93 60738 7742 2 930.464606 466.2402 Nucleophosmin OS=Homo sapiens OX=9606 GN=NPM1 PE=1 SV=2 4.37 1841.3 - 1.90E+06 - - - -1.3112 - 1.76 0.389 - 296.2 1 2 0 -0.0012 9 0 0 0 9.49E+07 1.02E+08 - - - 3.5493 0.9915 221125_WJC_METTL3_EV_vs_WT_F05.07743.07743.2 0.00358 20-Nov K.IANPVEGSSGR.Q sp|Q15365|PCBP1_HUMAN 1 1085.5465 0.92 60739 7743 2 1085.540371 543.7805 Poly(rC)-binding protein 1 OS=Homo sapiens OX=9606 GN=PCBP1 PE=1 SV=2 6 1841.4 - 1.05E+06 - - - -5.6792 - 2.207 0.338 - 433.2 1 2 0 -0.0062 11 0 0 0 1.42E+08 1.54E+08 - - - 3.6771 0.9997 221125_WJC_METTL3_EV_vs_WT_F05.07744.07744.2 6.26E-05 16-Sep R.QVSIEEGER.K "sp|P20340|RAB6A_HUMAN,sp|Q53S08|RAB6D_HUMAN" 2 1045.504 1.15 60740 7744 2 1045.503223 523.7593 Ras-related protein Rab-6A OS=Homo sapiens OX=9606 GN=RAB6A PE=1 SV=3 4.25 1841.5 - 3.37E+06 - - - -0.7461 - 1.608 0.454 - 337.9 1 2 0 -0.0008 9 0 0 0 7.79E+07 6.77E+07 - - - 3.7682 0.9977 221125_WJC_METTL3_EV_vs_WT_F05.07745.07745.2 6.56E-06 20-Nov R.LVSGLEAK[136.11]PDR[166.11].S sp|O15119|TBX3_HUMAN 1 1201.6786 0.87 60741 7745 2 1201.672686 601.8466 T-box transcription factor TBX3 OS=Homo sapiens OX=9606 GN=TBX3 PE=1 SV=4 6.07 1841.6 - 1.41E+06 - - - -4.8857 - 2.098 0.503 - 347.2 1 2 0 -0.0059 11 0 0 0 2.09E+07 2.40E+07 - - - 4.7589 0.9999 221125_WJC_METTL3_EV_vs_WT_F05.07749.07749.3 2.21E-06 Dec-44 K.AEPTAAPHPVLK.Q sp|Q86YP4|P66A_HUMAN 1 1229.6768 1.5 60743 7749 3 1229.674098 410.8996 Transcriptional repressor p66-alpha OS=Homo sapiens OX=9606 GN=GATAD2A PE=1 SV=1 6.79 1842.1 - 3.51E+06 - - - -2.2152 - 2.21 0.461 - 182.5 1 2 0 -0.0027 12 0 0 0 1.33E+08 8.84E+07 - - - 5.877 0.9934 221125_WJC_METTL3_EV_vs_WT_F05.07750.07750.3 0.0123 Aug-44 K.AEPTAAPHPVLK[136.11].Q sp|Q86YP4|P66A_HUMAN 1 1237.691 1.5 60744 7750 3 1237.688664 413.571 Transcriptional repressor p66-alpha OS=Homo sapiens OX=9606 GN=GATAD2A PE=1 SV=1 6.79 1842.2 - 2.23E+06 - - - -1.9052 - 1.767 0.204 - 49.2 1 2 0 -0.0024 12 0 0 0 1.33E+08 8.85E+07 - - - 2.3917 0.9999 221125_WJC_METTL3_EV_vs_WT_F05.07756.07756.2 6.17E-05 16-Nov R.QYEMGEC[160.03]TR[166.11].G "sp|Q01081|U2AF1_HUMAN,sp|Q8WU68|U2AF4_HUMAN" 2 1182.4673 1.06 60748 7756 2 1182.466018 592.2409 Splicing factor U2AF 35 kDa subunit OS=Homo sapiens OX=9606 GN=U2AF1 PE=1 SV=3 4.53 1842.9 - 1.10E+06 - - - -1.096 - 1.769 0.618 - 627.5 1 2 0 -0.0013 9 0 0 0 2.36E+07 2.23E+07 - - - 5.2554 0.9412 221125_WJC_METTL3_EV_vs_WT_F05.07757.07757.2 8.75 14-Jul K.R[166.11]AVDLIQK[136.11].H "sp|P39748|FEN1_HUMAN,tr|I3L3E9|I3L3E9_HUMAN" 2 959.5883 0.47 60749 7757 2 959.586179 480.8014 Flap endonuclease 1 OS=Homo sapiens OX=9606 GN=FEN1 PE=1 SV=1 8.75 1843 - 690270 - - - -2.1947 - 1.167 0.07 - 159.6 1 2 0 -0.0021 8 0 0 0 2.26E+07 4.78E+07 - - - 0.0231 0.9595 221125_WJC_METTL3_EV_vs_WT_F05.07758.07758.2 0.000389 18-Nov L.VSGLEAKPDR.S sp|O15119|TBX3_HUMAN 1 1070.572 0.66 60750 7758 2 1070.569682 536.2933 T-box transcription factor TBX3 OS=Homo sapiens OX=9606 GN=TBX3 PE=1 SV=4 6.04 1843.2 - 622419 - - - -2.1867 - 2.039 0.353 - 452.3 1 1 0 -0.0023 10 0 0 0 9.67E+06 1.45E+07 - - - 3.6362 0.9997 221125_WJC_METTL3_EV_vs_WT_F05.07759.07759.2 0.000335 16-Jul R.QELEGC[160.03]YEK.V "sp|Q4VCS5|AMOT_HUMAN,tr|A6NP16|A6NP16_HUMAN,tr|E7ERM3|E7ERM3_HUMAN" 3 1154.4914 2.78 60751 7759 2 1154.489829 578.253 Angiomotin OS=Homo sapiens OX=9606 GN=AMOT PE=1 SV=1 4.25 1843.3 - 463873 - - - -1.3521 - 1.595 0.465 - 161.8 1 2 0 -0.0016 9 0 0 0 6.67E+06 2.40E+06 - - - 3.8257 1 221125_WJC_METTL3_EV_vs_WT_F05.07760.07760.2 2.03E-10 17/28 R.GDVTAEEAAGASPAK.A sp|P49006|MRP_HUMAN 1 1372.647 0.85 60752 7760 2 1372.646475 687.3308 MARCKS-related protein OS=Homo sapiens OX=9606 GN=MARCKSL1 PE=1 SV=2 4.14 1843.4 - 458673 - - - -0.4102 - 3.299 0.683 - 1246.7 1 2 0 -0.0006 15 0 0 0 1.84E+07 2.17E+07 - - - 7.02 0.9996 221125_WJC_METTL3_EV_vs_WT_F05.07763.07763.2 5.01E-05 16-Oct R.QYEMGEC[160.03]TR.G "sp|Q01081|U2AF1_HUMAN,sp|Q8WU68|U2AF4_HUMAN" 2 1172.459 1.08 60753 7763 2 1172.456713 587.2368 Splicing factor U2AF 35 kDa subunit OS=Homo sapiens OX=9606 GN=U2AF1 PE=1 SV=3 4.53 1843.8 - 861563 - - - -1.9881 - 1.764 0.465 - 499.9 1 2 0 -0.0023 9 0 0 0 2.39E+07 2.23E+07 - - - 4.1168 0.9796 221125_WJC_METTL3_EV_vs_WT_F05.07764.07764.2 7.39 12-Apr K.EDDDAC[160.03]K.K "sp|Q86X67|NUD13_HUMAN,tr|A0A087X1G4|A0A087X1G4_HUMAN" 2 851.2967 1.13 60754 7764 2 851.29878 426.6556 "NAD(P)H pyrophosphatase NUDT13, mitochondrial OS=Homo sapiens OX=9606 GN=NUDT13 PE=2 SV=3" 3.84 1844 - 434876 - - - 2.4292 - 0.809 0.342 - 48.2 1 2 0 0.0021 7 0 0 0 1.63E+07 1.44E+07 - - - 0.8948 0.9983 221125_WJC_METTL3_EV_vs_WT_F05.07765.07765.2 9.74E-05 20-Sep R.LVSGLEAKPDR.S sp|O15119|TBX3_HUMAN 1 1183.6561 0.87 60755 7765 2 1183.652308 592.8353 T-box transcription factor TBX3 OS=Homo sapiens OX=9606 GN=TBX3 PE=1 SV=4 6.07 1844.1 - 757714 - - - -3.1927 - 1.672 0.408 - 288.6 1 2 0 -0.0038 11 0 0 0 2.09E+07 2.40E+07 - - - 3.4438 0.942 221125_WJC_METTL3_EV_vs_WT_F05.07770.07770.2 1.07 16-Aug R.HSVGVVIGR[166.11].S "sp|Q92945|FUBP2_HUMAN,tr|M0R0I5|M0R0I5_HUMAN,tr|M0R0C6|M0R0C6_HUMAN,tr|A0A087WTP3|A0A087WTP3_HUMAN" 4 932.5431 0.9 60758 7770 2 932.541302 467.2788 Far upstream element-binding protein 2 OS=Homo sapiens OX=9606 GN=KHSRP PE=1 SV=4 9.76 1844.6 - 5.45E+06 - - - -1.9484 - 1.389 0.009 - 142.1 2 2 0 -0.0018 9 0 0 0 2.01E+08 2.23E+08 - - - -0.077 0.9647 221125_WJC_METTL3_EV_vs_WT_F05.07775.07775.2 0.00295 16-Jun K.DHTPSQELA.L "sp|Q86U44|MTA70_HUMAN,tr|H0YFV6|H0YFV6_HUMAN" 2 996.4512 - 60761 7775 2 996.450111 499.2329 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 4.35 1845.2 - 1.04E+07 - - - -1.132 - 1.358 0.425 - 81.2 1 1 0 -0.0011 9 0 0 0 - - - - - 3.065 0.9971 221125_WJC_METTL3_EV_vs_WT_F05.07776.07776.2 0.000817 22-Aug K.AEPTAAPHPVLK[136.11].Q sp|Q86YP4|P66A_HUMAN 1 1237.691 1.63 60762 7776 2 1237.686948 619.8528 Transcriptional repressor p66-alpha OS=Homo sapiens OX=9606 GN=GATAD2A PE=1 SV=1 6.79 1845.3 - 225256 - - - -3.2916 - 1.761 0.329 - 100.8 1 2 0 -0.0041 12 0 0 0 9.59E+06 5.88E+06 - - - 2.9586 1 221125_WJC_METTL3_EV_vs_WT_F05.07777.07777.3 1.85E-05 15/44 R.YLAEVAAGDDKK.G "sp|P63104|1433Z_HUMAN,tr|H0YB80|H0YB80_HUMAN,tr|E7EX29|E7EX29_HUMAN,tr|B7Z2E6|B7Z2E6_HUMAN,tr|B0AZS6|B0AZS6_HUMAN" 5 1278.6456 1.27 60763 7777 3 1278.645232 427.2225 14-3-3 protein zeta\delta OS=Homo sapiens OX=9606 GN=YWHAZ PE=1 SV=1 4.56 1845.5 - 672639 - - - -0.2737 - 2.574 0.466 - 227 1 2 0 -0.0003 12 0 0 0 1.26E+08 9.93E+07 - - - 6.356 0.9989 221125_WJC_METTL3_EV_vs_WT_F05.07779.07779.2 0.000764 18-Oct K.MEEANIQPNR[166.11].V "sp|P42704|LPPRC_HUMAN,tr|A0A804HI14|A0A804HI14_HUMAN,tr|A0A804HL40|A0A804HL40_HUMAN,tr|A0A804HKJ0|A0A804HKJ0_HUMAN,tr|A0A804HKR3|A0A804HKR3_HUMAN,tr|A0A0C4DG06|A0A0C4DG06_HUMAN,tr|A0A804HIN4|A0A804HIN4_HUMAN,tr|A0A804HLG8|A0A804HLG8_HUMAN,tr|A0A804HIV5|A0A804HIV5_HUMAN,tr|A0A804HHY9|A0A804HHY9_HUMAN,tr|A0A804HJH8|A0A804HJH8_HUMAN,tr|B8ZZ38|B8ZZ38_HUMAN,tr|A0A804HI40|A0A804HI40_HUMAN,tr|A0A804HJZ1|A0A804HJZ1_HUMAN,tr|C9JCA9|C9JCA9_HUMAN,tr|A0A804HIQ7|A0A804HIQ7_HUMAN,tr|A0A804HK30|A0A804HK30_HUMAN,tr|A0A804HKI2|A0A804HKI2_HUMAN,tr|A0A804HKR5|A0A804HKR5_HUMAN,tr|A0A804HKX0|A0A804HKX0_HUMAN,tr|A0A804HIG4|A0A804HIG4_HUMAN,tr|A0A804HK02|A0A804HK02_HUMAN" 22 1210.564 0.53 60765 7779 2 1210.568443 606.2893 "Leucine-rich PPR motif-containing protein, mitochondrial OS=Homo sapiens OX=9606 GN=LRPPRC PE=1 SV=3" 4.53 1845.7 - 394810 - - - 3.6776 - 2.04 0.477 - 552.4 1 2 0 0.0045 10 0 0 0 1.32E+07 2.48E+07 - - - 4.5528 0.9999 221125_WJC_METTL3_EV_vs_WT_F05.07782.07782.3 0.00018 14/40 R.LVSGLEAKPDR.S sp|O15119|TBX3_HUMAN 1 1183.6561 0.93 60766 7782 3 1183.65384 395.5593 T-box transcription factor TBX3 OS=Homo sapiens OX=9606 GN=TBX3 PE=1 SV=4 6.07 1846.1 - 3.66E+06 - - - -1.8984 - 2.296 0.451 - 250 1 2 0 -0.0022 11 0 0 0 2.09E+08 2.26E+08 - - - 5.9288 0.9937 221125_WJC_METTL3_EV_vs_WT_F05.07784.07784.2 0.00986 12-Aug R.K[136.11]ETEFLR[166.11].L "sp|Q9Y2H1|ST38L_HUMAN,sp|Q15208|STK38_HUMAN,tr|F5GY51|F5GY51_HUMAN,tr|I3L0D0|I3L0D0_HUMAN,tr|F5H7Z3|F5H7Z3_HUMAN" 5 939.5145 3.06 60768 7784 2 939.512779 470.7645 Serine\threonine-protein kinase 38-like OS=Homo sapiens OX=9606 GN=STK38L PE=1 SV=3 6.14 1846.3 - 5.77E+06 - - - -1.7807 - 1.601 0.116 - 274.9 1 2 0 -0.0017 7 0 0 0 5.50E+08 1.80E+08 - - - 1.3885 0.9996 221125_WJC_METTL3_EV_vs_WT_F05.07785.07785.2 0.00016 16-Sep R.SAQAFTHLK[136.11].A "sp|Q9UBU9|NXF1_HUMAN,tr|H0YDU0|H0YDU0_HUMAN" 2 1009.5436 61.2 60769 7785 2 1009.542302 505.7791 Nuclear RNA export factor 1 OS=Homo sapiens OX=9606 GN=NXF1 PE=1 SV=1 8.49 1846.3 - 1.49E+06 - - - -1.3154 - 1.758 0.392 - 309 1 2 0 -0.0013 9 0 0 0 1.33E+09 2.18E+07 - - - 3.5681 0.9558 221125_WJC_METTL3_EV_vs_WT_F05.07787.07787.2 0.00998 14-Aug E.ADLDITK[136.11]R[166.11].Q "sp|Q9BZW7|TSG10_HUMAN,sp|P62269|RS18_HUMAN,tr|B8ZZZ9|B8ZZZ9_HUMAN,tr|F8WA32|F8WA32_HUMAN,tr|A0A669KBL0|A0A669KBL0_HUMAN" 5 948.5359 0.84 60770 7787 2 948.536317 475.2752 Testis-specific gene 10 protein OS=Homo sapiens OX=9606 GN=TSGA10 PE=1 SV=1 6 1846.6 - 965998 - - - 0.4238 - 1.616 0.295 - 224 1 1 0 0.0004 8 0 0 0 2.19E+07 2.62E+07 - - - 2.6673 0.9994 221125_WJC_METTL3_EV_vs_WT_F05.07789.07789.2 0.00388 16-Aug K.GPSSVEDIK[136.11].A "sp|P06748|NPM_HUMAN,tr|E5RI98|E5RI98_HUMAN,tr|A0A7I2YQC0|A0A7I2YQC0_HUMAN,tr|A0A7I2V5J8|A0A7I2V5J8_HUMAN,tr|A0A7I2V5S2|A0A7I2V5S2_HUMAN" 5 938.48 0.93 60771 7789 2 938.478729 470.2473 Nucleophosmin OS=Homo sapiens OX=9606 GN=NPM1 PE=1 SV=2 4.37 1846.8 - 4.86E+06 - - - -1.382 - 1.552 0.391 - 214.1 1 2 0 -0.0013 9 0 0 0 9.48E+07 1.02E+08 - - - 3.2001 1 221125_WJC_METTL3_EV_vs_WT_F05.07791.07791.3 1.74E-06 13/44 R.YLAEVAAGDDK[136.11]K[136.11].G "sp|P63104|1433Z_HUMAN,tr|H0YB80|H0YB80_HUMAN,tr|E7EX29|E7EX29_HUMAN,tr|B7Z2E6|B7Z2E6_HUMAN,tr|B0AZS6|B0AZS6_HUMAN" 5 1294.674 1.27 60773 7791 3 1294.673057 432.5653 14-3-3 protein zeta\delta OS=Homo sapiens OX=9606 GN=YWHAZ PE=1 SV=1 4.56 1846.9 - 2.06E+06 - - - -0.7145 - 2.552 0.497 - 177.7 1 2 0 -0.0009 12 0 0 0 1.26E+08 9.93E+07 - - - 6.6777 0.999 221125_WJC_METTL3_EV_vs_WT_F05.07794.07794.2 0.000412 22-Nov R.YLAEVAAGDDKK.G "sp|P63104|1433Z_HUMAN,tr|H0YB80|H0YB80_HUMAN,tr|E7EX29|E7EX29_HUMAN,tr|B7Z2E6|B7Z2E6_HUMAN,tr|B0AZS6|B0AZS6_HUMAN" 5 1278.6456 1.3 60776 7794 2 1278.640887 640.3301 14-3-3 protein zeta\delta OS=Homo sapiens OX=9606 GN=YWHAZ PE=1 SV=1 4.56 1847.2 - 169382 - - - -3.6719 - 2.351 0.449 - 379.7 1 2 0 -0.0047 12 0 0 0 1.49E+07 1.15E+07 - - - 4.6051 0.9999 221125_WJC_METTL3_EV_vs_WT_F05.07796.07796.2 4.00E-06 28-Nov K.LGAGEGGEASVSPEK[136.11].T "sp|Q13428|TCOF_HUMAN,tr|E7ETY2|E7ETY2_HUMAN,tr|A0A3B3IS06|A0A3B3IS06_HUMAN,tr|A0A6I8PRA0|A0A6I8PRA0_HUMAN" 4 1394.6769 0.69 60778 7796 2 1394.675143 698.3457 Treacle protein OS=Homo sapiens OX=9606 GN=TCOF1 PE=1 SV=3 4.25 1847.5 - 133138 - - - -1.2512 - 2.292 0.533 - 317.3 1 2 0 -0.0017 15 0 0 0 1.76E+06 2.56E+06 - - - 5.0164 0.9946 221125_WJC_METTL3_EV_vs_WT_F05.07800.07800.2 2.49 14-Aug K.RVEDVLGK.G "sp|Q14204|DYHC1_HUMAN,tr|A0A7P0T8N2|A0A7P0T8N2_HUMAN,tr|A0A7P0T9C4|A0A7P0T9C4_HUMAN,tr|A0A7P0TBJ7|A0A7P0TBJ7_HUMAN,tr|A0A804HHY6|A0A804HHY6_HUMAN,tr|A0A7P0T9K2|A0A7P0T9K2_HUMAN,tr|A0A7P0TB64|A0A7P0TB64_HUMAN,tr|A0A2R8Y706|A0A2R8Y706_HUMAN,tr|A0A7P0T916|A0A7P0T916_HUMAN,tr|A0A7P0TB75|A0A7P0TB75_HUMAN,tr|A0A7P0T8W5|A0A7P0T8W5_HUMAN,tr|A0A7P0T9S3|A0A7P0T9S3_HUMAN,tr|A0A7P0TAF3|A0A7P0TAF3_HUMAN,tr|A0A7P0T9F1|A0A7P0T9F1_HUMAN,tr|A0A7P0TAW9|A0A7P0TAW9_HUMAN,tr|A0A2R8YGC7|A0A2R8YGC7_HUMAN,tr|A0A7P0TA13|A0A7P0TA13_HUMAN,tr|A0A7P0T934|A0A7P0T934_HUMAN,tr|A0A7P0TAV5|A0A7P0TAV5_HUMAN,tr|A0A7P0T9Y3|A0A7P0T9Y3_HUMAN,tr|A0A7P0T7V5|A0A7P0T7V5_HUMAN,tr|A0A7P0T9R4|A0A7P0T9R4_HUMAN,tr|A0A2R8Y5T0|A0A2R8Y5T0_HUMAN,tr|A0A7P0T990|A0A7P0T990_HUMAN,tr|A0A7P0T942|A0A7P0T942_HUMAN,tr|A0A2R8YFZ7|A0A2R8YFZ7_HUMAN,tr|A0A7P0T825|A0A7P0T825_HUMAN,tr|A0A2R8Y6H2|A0A2R8Y6H2_HUMAN,tr|A0A7P0TBC9|A0A7P0TBC9_HUMAN,tr|A0A7P0TAM4|A0A7P0TAM4_HUMAN" 30 914.5185 0.32 60780 7800 2 914.519111 458.2665 Cytoplasmic dynein 1 heavy chain 1 OS=Homo sapiens OX=9606 GN=DYNC1H1 PE=1 SV=5 6.07 1847.9 - 1.57E+06 - - - 0.6342 - 1.596 0.093 - 325.3 1 2 0 0.0006 8 0 0 0 7.26E+07 2.24E+08 - - - 1.1377 0.9985 221125_WJC_METTL3_EV_vs_WT_F05.07801.07801.2 0.0325 18-Sep K.QPVLSQTEAR.D sp|P28070|PSB4_HUMAN 1 1127.5935 1.19 60781 7801 2 1127.595749 564.804 Proteasome subunit beta type-4 OS=Homo sapiens OX=9606 GN=PSMB4 PE=1 SV=4 6 1848 - 1.16E+06 - - - 2.006 - 1.551 0.339 - 259.9 1 2 0 0.0023 10 0 0 0 1.93E+07 1.62E+07 - - - 2.7692 0.9893 221125_WJC_METTL3_EV_vs_WT_F05.07803.07803.2 0.241 14-Jul R.ISSSSFSR[166.11].V "sp|P05787|K2C8_HUMAN,tr|F8VUG2|F8VUG2_HUMAN,tr|Q8IWY7|Q8IWY7_HUMAN,tr|F8W1U3|F8W1U3_HUMAN,tr|F8VQY3|F8VQY3_HUMAN" 5 879.4326 2.14 60783 7803 2 879.429418 440.7236 "Keratin, type II cytoskeletal 8 OS=Homo sapiens OX=9606 GN=KRT8 PE=1 SV=7" 9.75 1848.2 - 715827 - - - -3.5796 - 1.428 0.253 - 148.3 1 2 0 -0.0031 8 0 0 0 1.73E+07 8.09E+06 - - - 1.9832 0.9998 221125_WJC_METTL3_EV_vs_WT_F05.07804.07804.2 0.00427 18-Sep K.MEEANIQPNR.V "sp|P42704|LPPRC_HUMAN,tr|A0A804HI14|A0A804HI14_HUMAN,tr|A0A804HL40|A0A804HL40_HUMAN,tr|A0A804HKJ0|A0A804HKJ0_HUMAN,tr|A0A804HKR3|A0A804HKR3_HUMAN,tr|A0A0C4DG06|A0A0C4DG06_HUMAN,tr|A0A804HIN4|A0A804HIN4_HUMAN,tr|A0A804HLG8|A0A804HLG8_HUMAN,tr|A0A804HIV5|A0A804HIV5_HUMAN,tr|A0A804HHY9|A0A804HHY9_HUMAN,tr|A0A804HJH8|A0A804HJH8_HUMAN,tr|B8ZZ38|B8ZZ38_HUMAN,tr|A0A804HI40|A0A804HI40_HUMAN,tr|A0A804HJZ1|A0A804HJZ1_HUMAN,tr|C9JCA9|C9JCA9_HUMAN,tr|A0A804HIQ7|A0A804HIQ7_HUMAN,tr|A0A804HK30|A0A804HK30_HUMAN,tr|A0A804HKI2|A0A804HKI2_HUMAN,tr|A0A804HKR5|A0A804HKR5_HUMAN,tr|A0A804HKX0|A0A804HKX0_HUMAN,tr|A0A804HIG4|A0A804HIG4_HUMAN,tr|A0A804HK02|A0A804HK02_HUMAN" 22 1200.5557 0.53 60784 7804 2 1200.555903 601.2851 "Leucine-rich PPR motif-containing protein, mitochondrial OS=Homo sapiens OX=9606 GN=LRPPRC PE=1 SV=3" 4.53 1848.3 - 502052 - - - 0.1516 - 2.074 0.462 - 407.4 1 2 0 0.0002 10 0 0 0 1.30E+07 2.46E+07 - - - 4.4895 1 221125_WJC_METTL3_EV_vs_WT_F05.07805.07805.2 6.79E-05 14/22 R.YLAEVAAGDDK[136.11]K[136.11].G "sp|P63104|1433Z_HUMAN,tr|H0YB80|H0YB80_HUMAN,tr|E7EX29|E7EX29_HUMAN,tr|B7Z2E6|B7Z2E6_HUMAN,tr|B0AZS6|B0AZS6_HUMAN" 5 1294.674 1.31 60785 7805 2 1294.672441 648.3443 14-3-3 protein zeta\delta OS=Homo sapiens OX=9606 GN=YWHAZ PE=1 SV=1 4.56 1848.4 - 324823 - - - -1.1903 - 2.737 0.563 - 751.1 1 2 0 -0.0015 12 0 0 0 1.49E+07 1.14E+07 - - - 5.8481 0.9996 221125_WJC_METTL3_EV_vs_WT_F05.07807.07807.2 6.80E-05 28-Jul K.LGAGEGGEASVSPEK.T "sp|Q13428|TCOF_HUMAN,tr|E7ETY2|E7ETY2_HUMAN,tr|A0A3B3IS06|A0A3B3IS06_HUMAN,tr|A0A6I8PRA0|A0A6I8PRA0_HUMAN" 4 1386.6627 0.69 60787 7807 2 1386.665571 694.3386 Treacle protein OS=Homo sapiens OX=9606 GN=TCOF1 PE=1 SV=3 4.25 1848.7 - 112589 - - - 2.0791 - 1.856 0.527 - 112 1 2 0 0.0029 15 0 0 0 1.76E+06 2.56E+06 - - - 4.4529 0.8929 221125_WJC_METTL3_EV_vs_WT_F05.07812.07812.2 0.217 16-Aug R.QIYNPPSGK.Y "sp|Q9BZZ5|API5_HUMAN,tr|G3V1C3|G3V1C3_HUMAN" 2 1002.5134 1.3 60790 7812 2 1002.507953 502.264 Apoptosis inhibitor 5 OS=Homo sapiens OX=9606 GN=API5 PE=1 SV=3 8.59 1849.2 - 1.38E+06 - - - -5.4782 - 1.363 0.17 - 227 1 2 0 -0.0055 9 0 0 0 4.33E+07 3.34E+07 - - - 1.1908 0.9938 221125_WJC_METTL3_EV_vs_WT_F05.07813.07813.2 0.776 14-Aug K.RLDLDAAK.T "sp|Q9Y371|SHLB1_HUMAN,tr|A0A087WW40|A0A087WW40_HUMAN" 2 900.5029 1.13 60791 7813 2 900.503507 451.2587 Endophilin-B1 OS=Homo sapiens OX=9606 GN=SH3GLB1 PE=1 SV=1 5.96 1849.3 - 1.35E+06 - - - 0.6952 - 1.761 0.042 - 327.6 1 2 0 0.0006 8 0 0 0 3.81E+07 3.38E+07 - - - 1.0577 0.9998 221125_WJC_METTL3_EV_vs_WT_F05.07817.07817.2 1.38E-05 18-Sep K.QPVLSQTEAR[166.11].D sp|P28070|PSB4_HUMAN 1 1137.6018 1.1 60795 7817 2 1137.602303 569.8082 Proteasome subunit beta type-4 OS=Homo sapiens OX=9606 GN=PSMB4 PE=1 SV=4 6 1849.7 - 631356 - - - 0.48 - 1.732 0.497 - 356.5 1 2 0 0.0005 10 0 0 0 1.97E+07 1.79E+07 - - - 4.2449 0.999 221125_WJC_METTL3_EV_vs_WT_F05.07821.07821.2 0.0152 18-Jul K.IAPPETPDSK[136.11].V sp|Q9NZI8|IF2B1_HUMAN 1 1061.5484 1.82 60797 7821 2 1061.549036 531.7815 Insulin-like growth factor 2 mRNA-binding protein 1 OS=Homo sapiens OX=9606 GN=IGF2BP1 PE=1 SV=2 4.37 1850.2 - 2.26E+06 - - - 0.5614 - 1.385 0.346 - 177.9 1 2 0 0.0006 10 0 0 0 4.16E+08 2.28E+08 - - - 2.5055 0.9711 221125_WJC_METTL3_EV_vs_WT_F05.07822.07822.2 0.0808 16-Oct E.SLLNQQSTK[136.11].E "sp|Q86U44|MTA70_HUMAN,tr|F5H6D8|F5H6D8_HUMAN,tr|H0YFV6|H0YFV6_HUMAN,tr|B4DTN4|B4DTN4_HUMAN" 4 1025.5597 0.01 60798 7822 2 1025.560326 513.7871 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 8.47 1850.3 - 1.75E+06 - - - 0.6358 - 1.886 0.31 - 278.5 1 1 0 0.0007 9 0 0 0 1.52E+06 1.36E+08 - - - 3.166 0.9989 221125_WJC_METTL3_EV_vs_WT_F05.07824.07824.3 0.000158 Dec-44 K.VGTIDDDPEYR[166.11]K[136.11].F sp|Q9BZI7|REN3B_HUMAN 1 1424.6902 1.1 60800 7824 3 1424.690748 475.904 Regulator of nonsense transcripts 3B OS=Homo sapiens OX=9606 GN=UPF3B PE=1 SV=1 4.23 1850.4 - 624256 - - - 0.3538 - 2.161 0.229 - 269.9 1 2 0 0.0005 12 0 0 0 1.68E+07 1.53E+07 - - - 3.2289 0.9931 221125_WJC_METTL3_EV_vs_WT_F05.07825.07825.2 0.104 14-Jun K.ELDGHVLK.C "sp|Q8TB72|PUM2_HUMAN,sp|Q14671|PUM1_HUMAN,tr|Q5T1Z8|Q5T1Z8_HUMAN,tr|H0YDK8|H0YDK8_HUMAN,tr|H0YC97|H0YC97_HUMAN,tr|A0A0C4DG68|A0A0C4DG68_HUMAN,tr|H0YEH2|H0YEH2_HUMAN,tr|Q5T1Z4|Q5T1Z4_HUMAN,tr|E9PR38|E9PR38_HUMAN" 9 909.492 1.58 60801 7825 2 909.491985 455.7533 Pumilio homolog 2 OS=Homo sapiens OX=9606 GN=PUM2 PE=1 SV=2 5.32 1850.6 - 564894 - - - 0.0033 - 1.227 0.164 - 138.3 1 2 0 0 8 0 0 0 7.38E+06 4.68E+06 - - - 0.8693 0.9991 221125_WJC_METTL3_EV_vs_WT_F05.07831.07831.2 0.00667 22-Aug R.ALQQNGAPGIAK.V sp|Q9BW60|ELOV1_HUMAN 1 1166.6408 1.37 60807 7831 2 1166.641342 584.3277 Elongation of very long chain fatty acids protein 1 OS=Homo sapiens OX=9606 GN=ELOVL1 PE=1 SV=1 8.8 1851.3 - 191879 - - - 0.4894 - 1.562 0.316 - 229.7 1 2 0 0.0006 12 0 0 0 4.23E+06 3.09E+06 - - - 2.5482 1 221125_WJC_METTL3_EV_vs_WT_F05.07832.07832.2 1.14E-10 26-Aug K.LVDAGEEC[160.03]DC[160.03]GTPK[136.11].E "sp|Q13443|ADAM9_HUMAN,tr|A0A7I2V2Z6|A0A7I2V2Z6_HUMAN,tr|A0A7I2V2E1|A0A7I2V2E1_HUMAN,tr|A0A7I2V4B3|A0A7I2V4B3_HUMAN,tr|A0A7I2V3B5|A0A7I2V3B5_HUMAN,tr|A0A7I2V3C1|A0A7I2V3C1_HUMAN,tr|A0A7I2V5N8|A0A7I2V5N8_HUMAN,tr|A0AVL1|A0AVL1_HUMAN,tr|A0A7I2V303|A0A7I2V303_HUMAN,tr|A0A7I2YQ97|A0A7I2YQ97_HUMAN,tr|F8WC54|F8WC54_HUMAN,tr|A0A7I2V3W3|A0A7I2V3W3_HUMAN" 12 1557.6531 1.68 60808 7832 2 1557.650699 779.8338 Disintegrin and metalloproteinase domain-containing protein 9 OS=Homo sapiens OX=9606 GN=ADAM9 PE=1 SV=1 3.92 1851.5 - 82087.9 - - - -1.5151 - 1.743 0.777 - 140.6 1 2 0 -0.0024 14 0 0 0 1.67E+06 9.95E+05 - - - 6.1735 0.998 221125_WJC_METTL3_EV_vs_WT_F05.07836.07836.2 0.877 16-Sep R.HSVGVVIGR.S "sp|Q92945|FUBP2_HUMAN,tr|M0R0I5|M0R0I5_HUMAN,tr|M0R0C6|M0R0C6_HUMAN,tr|A0A087WTP3|A0A087WTP3_HUMAN" 4 922.5348 0.9 60810 7836 2 922.535061 462.2747 Far upstream element-binding protein 2 OS=Homo sapiens OX=9606 GN=KHSRP PE=1 SV=4 9.76 1851.9 - 1.06E+07 - - - 0.2298 - 1.533 0.205 - 174.2 1 2 0 0.0002 9 0 0 0 2.01E+08 2.23E+08 - - - 1.7911 0.995 221125_WJC_METTL3_EV_vs_WT_F05.07839.07839.2 0.208 14-Jun K.EIQDLQSR.Q "sp|Q9H4A3|WNK1_HUMAN,tr|F5GWT4|F5GWT4_HUMAN,tr|B7Z613|B7Z613_HUMAN,tr|A0A6Q8PFM0|A0A6Q8PFM0_HUMAN" 4 987.4985 0.89 60813 7839 2 987.499774 494.7565 Serine\threonine-protein kinase WNK1 OS=Homo sapiens OX=9606 GN=WNK1 PE=1 SV=2 4.37 1852.2 - 867394 - - - 1.2668 - 1.42 0.177 - 127.4 1 2 0 0.0013 8 0 0 0 1.87E+07 2.10E+07 - - - 1.4055 0.9991 221125_WJC_METTL3_EV_vs_WT_F05.07840.07840.2 0.0545 14-Aug R.RFEDLGSR.C "sp|P49750|YLPM1_HUMAN,tr|H0YIQ2|H0YIQ2_HUMAN" 2 978.4883 3.01 60814 7840 2 978.4881 490.2514 YLP motif-containing protein 1 OS=Homo sapiens OX=9606 GN=YLPM1 PE=1 SV=4 6.07 1852.3 - 798689 - - - -0.1972 - 1.488 0.307 - 179.4 1 2 0 -0.0002 8 0 0 0 1.70E+07 5.65E+06 - - - 2.5071 0.9989 221125_WJC_METTL3_EV_vs_WT_F05.07842.07842.2 0.00911 12-Jul R.K[136.11]MPFTEK[136.11].L "sp|P12956|XRCC6_HUMAN,tr|B1AHC9|B1AHC9_HUMAN" 2 895.4808 0.92 60816 7842 2 895.481816 448.7477 X-ray repair cross-complementing protein 6 OS=Homo sapiens OX=9606 GN=XRCC6 PE=1 SV=2 8.59 1852.5 - 628796 - - - 1.1067 - 1.411 0.331 - 222.3 1 2 0 0.001 7 0 0 0 8.26E+06 9.00E+06 - - - 2.5764 0.9968 221125_WJC_METTL3_EV_vs_WT_F05.07843.07843.2 0.0572 14-Aug R.ETGVDLTK[136.11].D "sp|P38646|GRP75_HUMAN,tr|H0Y8K0|H0Y8K0_HUMAN,tr|A0A7I2V2G2|A0A7I2V2G2_HUMAN,tr|A0A7I2V3F7|A0A7I2V3F7_HUMAN,tr|A0A7I2YQB2|A0A7I2YQB2_HUMAN,tr|D6RCD7|D6RCD7_HUMAN" 6 869.4586 0.59 60817 7843 2 869.459586 435.7366 "Stress-70 protein, mitochondrial OS=Homo sapiens OX=9606 GN=HSPA9 PE=1 SV=2" 4.37 1852.7 - 502038 - - - 1.1766 - 1.41 0.221 - 185.3 1 2 0 0.001 8 0 0 0 7.49E+06 1.27E+07 - - - 1.7092 0.999 221125_WJC_METTL3_EV_vs_WT_F05.07845.07845.3 0.0277 Oct-40 K.LGPTEGRPQLK.G sp|O15235|RT12_HUMAN 1 1194.6721 0.49 60819 7845 3 1194.67493 399.2313 "28S ribosomal protein S12, mitochondrial OS=Homo sapiens OX=9606 GN=MRPS12 PE=1 SV=1" 8.75 1852.9 - 275872 - - - 2.3931 - 2.295 0.277 - 91 1 2 0 0.0029 11 0 0 0 1.93E+07 3.94E+07 - - - 3.9875 0.9796 221125_WJC_METTL3_EV_vs_WT_F05.07847.07847.2 0.00394 18-Oct L.AEVAAGDDK[136.11]K[136.11].G "sp|P63104|1433Z_HUMAN,tr|H0YB80|H0YB80_HUMAN,tr|E7EX29|E7EX29_HUMAN,tr|B7Z2E6|B7Z2E6_HUMAN,tr|B0AZS6|B0AZS6_HUMAN" 5 1018.5266 1.07 60821 7847 2 1018.525933 510.2706 14-3-3 protein zeta\delta OS=Homo sapiens OX=9606 GN=YWHAZ PE=1 SV=1 4.56 1853.2 - 181688 - - - -0.6441 - 1.736 0.392 - 337.5 1 1 0 -0.0007 10 0 0 0 1.48E+06 1.38E+06 - - - 3.4757 1 221125_WJC_METTL3_EV_vs_WT_F05.07851.07851.3 9.97E-05 16/44 K.VGTIDDDPEYRK.F sp|Q9BZI7|REN3B_HUMAN 1 1406.6678 1.1 60823 7851 3 1406.668565 469.8965 Regulator of nonsense transcripts 3B OS=Homo sapiens OX=9606 GN=UPF3B PE=1 SV=1 4.23 1853.7 - 1.31E+06 - - - 0.5623 - 2.918 0.484 - 462.5 1 2 0 0.0008 12 0 0 0 1.68E+07 1.53E+07 - - - 6.9043 0.9907 221125_WJC_METTL3_EV_vs_WT_F05.07852.07852.2 0.151 12-Aug R.KMPFTEK.L "sp|P12956|XRCC6_HUMAN,tr|B1AHC9|B1AHC9_HUMAN" 2 879.4524 0.69 60824 7852 2 879.454647 440.7335 X-ray repair cross-complementing protein 6 OS=Homo sapiens OX=9606 GN=XRCC6 PE=1 SV=2 8.59 1853.8 - 687863 - - - 2.5266 - 1.387 0.195 - 292.7 1 2 0 0.0022 7 0 0 0 8.52E+06 1.23E+07 - - - 1.5171 1 221125_WJC_METTL3_EV_vs_WT_F05.07856.07856.2 4.34E-07 13/24 R.APGAEEDDSELQR.A "sp|Q53F19|NCBP3_HUMAN,tr|K7ELP6|K7ELP6_HUMAN" 2 1415.6165 1.83 60828 7856 2 1415.618678 708.8155 Nuclear cap-binding protein subunit 3 OS=Homo sapiens OX=9606 GN=NCBP3 PE=1 SV=2 3.83 1854.3 - 128461 - - - 1.5626 - 2.609 0.689 - 775.1 1 2 0 0.0022 13 0 0 0 5.17E+06 2.83E+06 - - - 6.5905 0.9925 221125_WJC_METTL3_EV_vs_WT_F05.07857.07857.2 0.119 24-Aug K.IAENPANPPVGGK.A "sp|Q641Q2|WAC2A_HUMAN,sp|Q9Y4E1|WAC2C_HUMAN,tr|F8W7U3|F8W7U3_HUMAN,tr|J3KP36|J3KP36_HUMAN,tr|E7ESD2|E7ESD2_HUMAN,tr|A0A0A0MR88|A0A0A0MR88_HUMAN,tr|A0A087WYF6|A0A087WYF6_HUMAN,tr|A0A096LPC5|A0A096LPC5_HUMAN" 8 1262.6619 1.92 60829 7857 2 1262.664282 632.3382 WASH complex subunit 2A OS=Homo sapiens OX=9606 GN=WASHC2A PE=1 SV=3 6 1854.4 - 125766 - - - 1.8865 - 1.3 0.224 - 144.2 1 2 0 0.0024 13 0 0 0 2.11E+06 1.10E+06 - - - 1.3681 0.9996 221125_WJC_METTL3_EV_vs_WT_F05.07863.07863.2 0.242 14-Sep R.KEPLETLK.S "sp|Q5VT66|MARC1_HUMAN,tr|H7BYZ9|H7BYZ9_HUMAN,tr|X6RIL1|X6RIL1_HUMAN,tr|A0A494C1P3|A0A494C1P3_HUMAN" 4 956.5542 1.38 60833 7863 2 956.554879 479.2844 Mitochondrial amidoxime-reducing component 1 OS=Homo sapiens OX=9606 GN=MTARC1 PE=1 SV=1 6.14 1855.2 - 623948 - - - 0.6607 - 1.962 0.306 - 299.2 1 2 0 0.0006 8 0 0 0 1.66E+07 1.20E+07 - - - 3.3336 0.9996 221125_WJC_METTL3_EV_vs_WT_F05.07868.07868.2 3.69E-05 13/26 K.LAAVAQGEEENASR.S sp|Q8IWJ2|GCC2_HUMAN 1 1443.6954 1.99 60838 7868 2 1443.699652 722.855 GRIP and coiled-coil domain-containing protein 2 OS=Homo sapiens OX=9606 GN=GCC2 PE=1 SV=4 4.25 1855.8 - 185402 - - - 2.9549 - 2.68 0.527 - 517.9 1 2 0 0.0043 14 0 0 0 1.66E+07 8.36E+06 - - - 5.4059 0.9999 221125_WJC_METTL3_EV_vs_WT_F05.07870.07870.2 0.000306 16/26 K.LAAVAQGEEENASR[166.11].S sp|Q8IWJ2|GCC2_HUMAN 1 1453.7037 1.99 60840 7870 2 1453.702298 727.8591 GRIP and coiled-coil domain-containing protein 2 OS=Homo sapiens OX=9606 GN=GCC2 PE=1 SV=4 4.25 1856.1 - 118241 - - - -0.9342 - 2.623 0.487 - 879.3 1 2 0 -0.0014 14 0 0 0 1.66E+07 8.36E+06 - - - 5.0575 1 221125_WJC_METTL3_EV_vs_WT_F05.07871.07871.2 8.13E-08 13/24 K.LEEANGNTQMVEK.L sp|O94906|PRP6_HUMAN 1 1461.677 2.8 60841 7871 2 1461.681392 731.8458 Pre-mRNA-processing factor 6 OS=Homo sapiens OX=9606 GN=PRPF6 PE=1 SV=1 4.25 1856.2 - 113186 - - - 3.0335 - 2.916 0.629 - 576.7 1 2 0 0.0044 13 0 0 0 1.66E+07 5.93E+06 - - - 6.4321 0.9998 221125_WJC_METTL3_EV_vs_WT_F05.07873.07873.2 0.000204 20-Oct K.MDSTEPPYSQK[136.11].R "sp|P68104|EF1A1_HUMAN,sp|Q5VTE0|EF1A3_HUMAN,tr|A0A7I2V659|A0A7I2V659_HUMAN,tr|A0A7I2V3H3|A0A7I2V3H3_HUMAN,tr|A0A7I2V5N4|A0A7I2V5N4_HUMAN,tr|A0A087WVQ9|A0A087WVQ9_HUMAN,tr|A0A087WV01|A0A087WV01_HUMAN" 7 1289.5689 0.57 60842 7873 2 1289.570557 645.7917 Elongation factor 1-alpha 1 OS=Homo sapiens OX=9606 GN=EEF1A1 PE=1 SV=1 4.37 1856.6 - 435360 - - - 1.271 - 2.121 0.445 - 264.3 1 2 0 0.0016 11 0 0 0 8.64E+06 1.52E+07 - - - 4.3613 0.993 221125_WJC_METTL3_EV_vs_WT_F05.07877.07877.2 0.000524 20-Dec L.FASGEGDYSTR[166.11].H sp|P13674|P4HA1_HUMAN 1 1198.513 1.91 60845 7877 2 1198.513519 600.2638 Prolyl 4-hydroxylase subunit alpha-1 OS=Homo sapiens OX=9606 GN=P4HA1 PE=1 SV=2 4.37 1857 - 403738 - - - 0.4322 - 2.129 0.535 - 399.1 1 1 0 0.0005 11 0 0 0 6.05E+06 3.16E+06 - - - 5.0366 1 221125_WJC_METTL3_EV_vs_WT_F05.07879.07879.3 0.00294 Nov-36 K.MTEVLDHEER[166.11].V sp|Q9UBB9|TFP11_HUMAN 1 1267.5742 1.35 60847 7879 3 1267.575889 423.532 Tuftelin-interacting protein 11 OS=Homo sapiens OX=9606 GN=TFIP11 PE=1 SV=1 4.4 1857.3 - 327604 - - - 1.3159 - 2.616 0.46 - 242.4 1 2 0 0.0017 10 0 0 0 5.98E+06 4.43E+06 - - - 6.4765 1 221125_WJC_METTL3_EV_vs_WT_F05.07881.07881.2 3.82E-10 24-Nov R.APGAEEDDSELQR[166.11].A "sp|Q53F19|NCBP3_HUMAN,tr|K7ELP6|K7ELP6_HUMAN" 2 1425.6247 1.83 60849 7881 2 1425.623072 713.8196 Nuclear cap-binding protein subunit 3 OS=Homo sapiens OX=9606 GN=NCBP3 PE=1 SV=2 3.83 1857.6 - 207419 - - - -1.1672 - 2.665 0.61 - 470.8 1 2 0 -0.0017 13 0 0 0 5.17E+06 2.83E+06 - - - 6.0617 1 221125_WJC_METTL3_EV_vs_WT_F05.07882.07882.2 8.97E-05 13/24 K.LEEANGNTQMVEK[136.11].L sp|O94906|PRP6_HUMAN 1 1469.6912 2.8 60850 7882 2 1469.69031 735.8529 Pre-mRNA-processing factor 6 OS=Homo sapiens OX=9606 GN=PRPF6 PE=1 SV=1 4.25 1857.7 - 206925 - - - -0.577 - 2.786 0.571 - 548.5 1 2 0 -0.0008 13 0 0 0 1.66E+07 5.93E+06 - - - 5.8878 0.9848 221125_WJC_METTL3_EV_vs_WT_F05.07883.07883.2 0.17 24-May K.IAENPANPPVGGK[136.11].A "sp|Q641Q2|WAC2A_HUMAN,sp|Q9Y4E1|WAC2C_HUMAN,tr|F8W7U3|F8W7U3_HUMAN,tr|J3KP36|J3KP36_HUMAN,tr|E7ESD2|E7ESD2_HUMAN,tr|A0A0A0MR88|A0A0A0MR88_HUMAN,tr|A0A087WYF6|A0A087WYF6_HUMAN,tr|A0A096LPC5|A0A096LPC5_HUMAN" 8 1270.6761 2.21 60851 7883 2 1270.675745 636.3453 WASH complex subunit 2A OS=Homo sapiens OX=9606 GN=WASHC2A PE=1 SV=3 6 1857.8 - 96065.1 - - - -0.2794 - 1.057 0.156 - 69.6 1 2 0 -0.0004 13 0 0 0 4.40E+06 1.99E+06 - - - 0.3354 0.9969 221125_WJC_METTL3_EV_vs_WT_F05.07887.07887.2 0.00217 16-Oct K.VSELK[136.11]EELK[136.11].K "sp|Q00839|HNRPU_HUMAN,tr|A0A1W2PPS1|A0A1W2PPS1_HUMAN,tr|A0A1X7SBS1|A0A1X7SBS1_HUMAN" 3 1089.6252 1.13 60853 7887 2 1089.625616 545.8199 Heterogeneous nuclear ribonucleoprotein U OS=Homo sapiens OX=9606 GN=HNRNPU PE=1 SV=6 4.79 1858.3 - 2.17E+06 - - - 0.3442 - 1.838 0.394 - 386.4 1 2 1 0.0004 9 0 0 0 5.15E+08 4.56E+08 - - - 3.7119 0.9998 221125_WJC_METTL3_EV_vs_WT_F05.07890.07890.2 0.000267 20-Dec R.EALGDAQQSVR[166.11].L "sp|Q99615|DNJC7_HUMAN,tr|A0A6I8PR93|A0A6I8PR93_HUMAN,tr|K7ESP1|K7ESP1_HUMAN,tr|A0A6I8PRZ0|A0A6I8PRZ0_HUMAN,tr|A0A6I8PLE7|A0A6I8PLE7_HUMAN,tr|K7EJE9|K7EJE9_HUMAN,tr|A0A6I8PR89|A0A6I8PR89_HUMAN,tr|A0A6I8PIK4|A0A6I8PIK4_HUMAN,tr|K7ELJ8|K7ELJ8_HUMAN,tr|K7EN19|K7EN19_HUMAN,tr|A0A6I8PUC2|A0A6I8PUC2_HUMAN,tr|A0A6I8PS32|A0A6I8PS32_HUMAN,tr|K7EJL5|K7EJL5_HUMAN,tr|K7EPP7|K7EPP7_HUMAN,tr|A0A6I8PUD4|A0A6I8PUD4_HUMAN,tr|K7EIH8|K7EIH8_HUMAN,tr|K7ER44|K7ER44_HUMAN,tr|A0A6I8PU73|A0A6I8PU73_HUMAN,tr|K7EK03|K7EK03_HUMAN,tr|K7EJV7|K7EJV7_HUMAN,tr|A0A6I8PU89|A0A6I8PU89_HUMAN" 21 1182.5868 0.77 60856 7890 2 1182.587576 592.3007 DnaJ homolog subfamily C member 7 OS=Homo sapiens OX=9606 GN=DNAJC7 PE=1 SV=2 4.37 1858.5 - 1.25E+06 - - - 0.6266 - 2.238 0.469 - 548.6 1 2 0 0.0007 11 0 0 0 5.36E+07 6.96E+07 - - - 4.6841 1 221125_WJC_METTL3_EV_vs_WT_F05.07893.07893.2 1.95E-08 17/28 R.GGPGGPGGPGGPMGR.M "sp|Q01844|EWS_HUMAN,tr|B0QYK0|B0QYK0_HUMAN,tr|H7BY36|H7BY36_HUMAN,tr|A0A0D9SFL3|A0A0D9SFL3_HUMAN,tr|C9JGE3|C9JGE3_HUMAN" 5 1206.5564 0.8 60859 7893 2 1206.557483 604.2855 RNA-binding protein EWS OS=Homo sapiens OX=9606 GN=EWSR1 PE=1 SV=1 9.75 1858.8 - 988699 - - - 0.9059 - 3.077 0.617 - 1048.1 1 2 0 0.0011 15 0 0 0 2.39E+08 2.97E+08 - - - 6.3611 0.9326 221125_WJC_METTL3_EV_vs_WT_F05.07896.07896.2 1.21 12-Aug L.PLSSQHR[166.11].G "sp|P43243|MATR3_HUMAN,tr|A8MXP9|A8MXP9_HUMAN,tr|D6R991|D6R991_HUMAN,tr|A0A0R4J2E8|A0A0R4J2E8_HUMAN,tr|D6R8Z5|D6R8Z5_HUMAN,tr|D6REM6|D6REM6_HUMAN" 6 833.4383 1.28 60862 7896 2 833.438159 417.7264 Matrin-3 OS=Homo sapiens OX=9606 GN=MATR3 PE=1 SV=2 10.18 1859.2 - 675960 - - - -0.1932 - 1.626 0.22 - 230.7 1 1 0 -0.0002 7 0 0 0 9.72E+08 7.57E+08 - - - 2.2062 0.9998 221125_WJC_METTL3_EV_vs_WT_F05.07897.07897.2 2.57E-05 20-Oct K.MDSTEPPYSQK.R "sp|P68104|EF1A1_HUMAN,sp|Q5VTE0|EF1A3_HUMAN,tr|A0A7I2V659|A0A7I2V659_HUMAN,tr|A0A7I2V3H3|A0A7I2V3H3_HUMAN,tr|A0A7I2V5N4|A0A7I2V5N4_HUMAN,tr|A0A087WVQ9|A0A087WVQ9_HUMAN,tr|A0A087WV01|A0A087WV01_HUMAN" 7 1281.5547 0.57 60863 7897 2 1281.553584 641.7846 Elongation factor 1-alpha 1 OS=Homo sapiens OX=9606 GN=EEF1A1 PE=1 SV=1 4.37 1859.3 - 436573 - - - -0.8849 - 2.225 0.468 - 273.3 1 2 0 -0.0011 11 0 0 0 8.64E+06 1.51E+07 - - - 4.6608 0.7743 221125_WJC_METTL3_EV_vs_WT_F05.07899.07899.2 0.147 20-Jul K.VEQIEAGTPGR[166.11].L "sp|Q16881|TRXR1_HUMAN,tr|F8W809|F8W809_HUMAN,tr|A0A087WSW9|A0A087WSW9_HUMAN,tr|A0A182DWI3|A0A182DWI3_HUMAN,tr|A0A087WSY9|A0A087WSY9_HUMAN,tr|E9PIR7|E9PIR7_HUMAN,tr|E2QRB9|E2QRB9_HUMAN" 7 1165.5967 0.96 60865 7899 2 1165.588716 583.8056 "Thioredoxin reductase 1, cytoplasmic OS=Homo sapiens OX=9606 GN=TXNRD1 PE=1 SV=3" 4.53 1859.6 - 304357 - - - -6.8248 - 1.174 0.236 - 91.8 1 2 0 -0.008 11 0 0 0 8.43E+05 8.79E+05 - - - 1.2156 0.9999 221125_WJC_METTL3_EV_vs_WT_F05.07900.07900.2 0.000223 20-Jul R.AEFEDQDDEAR.V sp|Q14692|BMS1_HUMAN 1 1323.5215 1.84 60866 7900 2 1323.520491 662.768 Ribosome biogenesis protein BMS1 homolog OS=Homo sapiens OX=9606 GN=BMS1 PE=1 SV=1 3.71 1859.7 - 231528 - - - -0.7646 - 1.574 0.642 - 139.1 1 2 0 -0.001 11 0 0 0 2.35E+06 1.27E+06 - - - 5.0096 0.9976 221125_WJC_METTL3_EV_vs_WT_F05.07905.07905.2 0.138 13/16 K.VSELKEELK.K "sp|Q00839|HNRPU_HUMAN,tr|A0A1W2PPS1|A0A1W2PPS1_HUMAN,tr|A0A1X7SBS1|A0A1X7SBS1_HUMAN" 3 1073.5968 1.08 60869 7905 2 1073.596888 537.8057 Heterogeneous nuclear ribonucleoprotein U OS=Homo sapiens OX=9606 GN=HNRNPU PE=1 SV=6 4.79 1860.4 - 7.19E+06 - - - 0.0438 - 2.528 0.31 - 974 1 2 1 0 9 0 0 0 4.91E+08 4.55E+08 - - - 4.0137 1 221125_WJC_METTL3_EV_vs_WT_F05.07907.07907.2 7.88E-08 14/28 R.GGPGGPGGPGGPMGR[166.11].M "sp|Q01844|EWS_HUMAN,tr|B0QYK0|B0QYK0_HUMAN,tr|H7BY36|H7BY36_HUMAN,tr|A0A0D9SFL3|A0A0D9SFL3_HUMAN,tr|C9JGE3|C9JGE3_HUMAN" 5 1216.5647 0.8 60871 7907 2 1216.563717 609.2896 RNA-binding protein EWS OS=Homo sapiens OX=9606 GN=EWSR1 PE=1 SV=1 9.75 1860.5 - 3.70E+06 - - - -0.7751 - 2.789 0.683 - 682.1 1 2 0 -0.0009 15 0 0 0 2.38E+08 2.97E+08 - - - 6.607 0.997 221125_WJC_METTL3_EV_vs_WT_F05.07911.07911.2 0.00144 14-Jul K.DDNPNLPR.L "sp|P02768|ALBU_HUMAN,tr|A0A087WWT3|A0A087WWT3_HUMAN,tr|H7C013|H7C013_HUMAN,tr|A0A0C4DGB6|A0A0C4DGB6_HUMAN" 4 939.441 7.76 60875 7911 2 939.444362 470.7278 Albumin OS=Homo sapiens OX=9606 GN=ALB PE=1 SV=2 4.21 1860.9 - 849262 - - - 3.5691 - 1.514 0.388 - 258.2 1 2 0 0.0034 8 0 0 0 1.48E+08 1.91E+07 - - - 3.1566 0.9999 221125_WJC_METTL3_EV_vs_WT_F05.07912.07912.2 1.29E-06 22-Dec K.IAQGVSGSIQDK.G "sp|P20839|IMDH1_HUMAN,tr|C9J381|C9J381_HUMAN,tr|A0A3B3IRL5|A0A3B3IRL5_HUMAN" 3 1201.6303 1.44 60876 7912 2 1201.629708 601.8224 Inosine-5'-monophosphate dehydrogenase 1 OS=Homo sapiens OX=9606 GN=IMPDH1 PE=1 SV=2 5.84 1861 - 633403 - - - -0.4644 - 2.496 0.489 - 452.8 1 2 0 -0.0006 12 0 0 0 9.61E+06 6.69E+06 - - - 5.0593 1 221125_WJC_METTL3_EV_vs_WT_F05.07914.07914.3 2.73E-06 15/40 R.AAAEEGHIIPR[166.11].S "sp|O95551|TYDP2_HUMAN,tr|X6R5A3|X6R5A3_HUMAN" 2 1172.6177 0.51 60878 7914 3 1172.616067 391.8799 Tyrosyl-DNA phosphodiesterase 2 OS=Homo sapiens OX=9606 GN=TDP2 PE=1 SV=1 5.4 1861.3 - 564509 - - - -1.4276 - 3.055 0.52 - 455.7 1 2 0 -0.0017 11 0 0 0 9.23E+06 1.80E+07 - - - 7.5096 0.9995 221125_WJC_METTL3_EV_vs_WT_F05.07920.07920.2 0.0368 12-Aug K.FDSEYER.M "sp|P43243|MATR3_HUMAN,tr|A8MXP9|A8MXP9_HUMAN,tr|D6R991|D6R991_HUMAN,tr|A0A0R4J2E8|A0A0R4J2E8_HUMAN,tr|H0Y8T4|H0Y8T4_HUMAN,tr|D6REM6|D6REM6_HUMAN" 6 944.3876 1.77 60882 7920 2 944.386534 473.2011 Matrin-3 OS=Homo sapiens OX=9606 GN=MATR3 PE=1 SV=2 4.14 1862 - 1.53E+06 - - - -1.1034 - 1.714 0.353 - 205.9 1 2 0 -0.001 7 0 0 0 4.24E+07 2.40E+07 - - - 3.3552 0.9993 221125_WJC_METTL3_EV_vs_WT_F05.07921.07921.2 0.000277 12-Aug R.YNYLKPR.A sp|P56385|ATP5I_HUMAN 1 952.5131 1.4 60883 7921 2 952.513229 477.2638 "ATP synthase subunit e, mitochondrial OS=Homo sapiens OX=9606 GN=ATP5ME PE=1 SV=2" 9.7 1862.1 - 1.36E+06 - - - 0.1869 - 1.782 0.242 - 294.7 1 2 0 0.0002 7 0 0 0 6.73E+07 4.82E+07 - - - 2.6589 0.9982 221125_WJC_METTL3_EV_vs_WT_F05.07922.07922.2 0.000505 16-Nov R.VAQILK[136.11]EPK[136.11].V "sp|P48047|ATPO_HUMAN,tr|H7C0C1|H7C0C1_HUMAN,tr|A0A494C0K9|A0A494C0K9_HUMAN" 3 1040.6565 1 60884 7922 2 1040.656254 521.3355 "ATP synthase subunit O, mitochondrial OS=Homo sapiens OX=9606 GN=ATP5PO PE=1 SV=1" 8.56 1862.2 - 1.25E+06 - - - -0.2181 - 2.364 0.392 - 536.3 1 2 1 -0.0002 9 0 0 0 4.12E+07 4.13E+07 - - - 4.4253 0.9998 221125_WJC_METTL3_EV_vs_WT_F05.07923.07923.2 0.00226 14-Dec K.HFELGGDK.K "sp|P83881|RL36A_HUMAN,sp|Q969Q0|RL36L_HUMAN,tr|H0Y5B4|H0Y5B4_HUMAN,tr|J3KQN4|J3KQN4_HUMAN,tr|R4GN19|R4GN19_HUMAN,tr|H7BZ11|H7BZ11_HUMAN" 6 901.4294 0.94 60885 7923 2 901.428134 451.722 60S ribosomal protein L36a OS=Homo sapiens OX=9606 GN=RPL36A PE=1 SV=2 5.32 1862.4 - 1.15E+06 - - - -1.3834 - 2.039 0.437 - 400.1 1 2 0 -0.0012 8 0 0 0 6.33E+07 6.72E+07 - - - 4.417 0.9999 221125_WJC_METTL3_EV_vs_WT_F05.07925.07925.2 3.63E-07 22-Dec K.AAMDNSEIAGEK[136.11].K "sp|Q16891|MIC60_HUMAN,tr|B9A067|B9A067_HUMAN,tr|C9J406|C9J406_HUMAN,tr|H7C463|H7C463_HUMAN" 4 1242.5642 1.61 60887 7925 2 1242.562853 622.2894 MICOS complex subunit MIC60 OS=Homo sapiens OX=9606 GN=IMMT PE=1 SV=1 4.14 1862.6 - 1.01E+06 - - - -1.0575 - 2.528 0.507 - 501.9 1 2 0 -0.0013 12 0 0 0 6.38E+07 3.96E+07 - - - 5.2255 0.9986 221125_WJC_METTL3_EV_vs_WT_F05.07927.07927.2 0.0671 18-Nov K.EVTELSQEEK.K sp|O00716|E2F3_HUMAN 1 1190.5667 1.17 60889 7927 2 1190.564589 596.2906 Transcription factor E2F3 OS=Homo sapiens OX=9606 GN=E2F3 PE=1 SV=1 4.09 1862.8 - 585663 - - - -1.742 - 1.834 0.251 - 420.6 1 2 0 -0.0021 10 0 0 0 6.46E+06 5.53E+06 - - - 2.5872 0.9999 221125_WJC_METTL3_EV_vs_WT_F05.07928.07928.2 2.95E-06 16-Oct R.TYSQDC[160.03]SFK.N "sp|Q86U86|PB1_HUMAN,tr|H0Y5B5|H0Y5B5_HUMAN,tr|E7EVG2|E7EVG2_HUMAN" 3 1134.4652 1.57 60890 7928 2 1134.463814 568.2399 Protein polybromo-1 OS=Homo sapiens OX=9606 GN=PBRM1 PE=1 SV=1 5.5 1863 - 581517 - - - -1.1997 - 1.833 0.648 - 259.7 1 2 0 -0.0014 9 0 0 0 2.77E+07 1.77E+07 - - - 5.5798 0.9727 221125_WJC_METTL3_EV_vs_WT_F05.07929.07929.3 0.108 Sep-36 K.LNVEAVNTHR[166.11].D "sp|O60825|F262_HUMAN,sp|P16118|F261_HUMAN,tr|I1Z9G3|I1Z9G3_HUMAN,tr|Q4VBA9|Q4VBA9_HUMAN" 4 1161.613 2.07 60891 7929 3 1161.60911 388.2116 "6-phosphofructo-2-kinase\fructose-2,6-bisphosphatase 2 OS=Homo sapiens OX=9606 GN=PFKFB2 PE=1 SV=2" 6.75 1863.1 - 422920 - - - -3.3402 - 1.741 0.178 - 78.7 1 2 0 -0.0039 10 0 0 0 3.16E+07 1.53E+07 - - - 2.1427 0.904 221125_WJC_METTL3_EV_vs_WT_F05.07930.07930.2 1.46 14-Aug R.LK[136.11]EVFQTK[136.11].L "sp|Q9Y6D9|MD1L1_HUMAN,tr|C9JKI7|C9JKI7_HUMAN" 2 1007.5986 0.06 60892 7930 2 1007.597546 504.8066 Mitotic spindle assembly checkpoint protein MAD1 OS=Homo sapiens OX=9606 GN=MAD1L1 PE=1 SV=2 8.59 1863.2 - 395334 - - - -1.0778 - 1.32 0.126 - 128.6 1 2 1 -0.0011 8 0 0 0 3.83E+05 6.22E+06 - - - 0.8086 1 221125_WJC_METTL3_EV_vs_WT_F05.07934.07934.2 4.47E-06 22-Nov K.AAMDNSEIAGEK.K "sp|Q16891|MIC60_HUMAN,tr|B9A067|B9A067_HUMAN,tr|C9J406|C9J406_HUMAN,tr|H7C463|H7C463_HUMAN" 4 1234.55 1.61 60894 7934 2 1234.549319 618.2823 MICOS complex subunit MIC60 OS=Homo sapiens OX=9606 GN=IMMT PE=1 SV=1 4.14 1863.8 - 2.78E+06 - - - -0.5249 - 2.386 0.637 - 371.4 1 2 0 -0.0006 12 0 0 0 6.38E+07 3.96E+07 - - - 6.0338 0.9997 221125_WJC_METTL3_EV_vs_WT_F05.07935.07935.2 0.0171 14-Nov K.HFELGGDK[136.11].K "sp|P83881|RL36A_HUMAN,sp|Q969Q0|RL36L_HUMAN,tr|H0Y5B4|H0Y5B4_HUMAN,tr|J3KQN4|J3KQN4_HUMAN,tr|R4GN19|R4GN19_HUMAN,tr|H7BZ11|H7BZ11_HUMAN" 6 909.4436 0.94 60895 7935 2 909.442611 455.7291 60S ribosomal protein L36a OS=Homo sapiens OX=9606 GN=RPL36A PE=1 SV=2 5.32 1863.8 - 2.64E+06 - - - -1.0666 - 1.822 0.401 - 361.4 1 2 0 -0.001 8 0 0 0 6.30E+07 6.72E+07 - - - 3.8119 0.9984 221125_WJC_METTL3_EV_vs_WT_F05.07936.07936.2 0.00188 16-Sep K.ATQSYLQEK.V "sp|P49750|YLPM1_HUMAN,tr|H0YIQ2|H0YIQ2_HUMAN,tr|F8VU51|F8VU51_HUMAN" 3 1066.5295 1.38 60896 7936 2 1066.526805 534.272 YLP motif-containing protein 1 OS=Homo sapiens OX=9606 GN=YLPM1 PE=1 SV=4 6.05 1863.9 - 2.28E+06 - - - -2.5166 - 1.419 0.402 - 249.2 1 2 0 -0.0027 9 0 0 0 5.98E+07 4.33E+07 - - - 3.0218 0.9998 221125_WJC_METTL3_EV_vs_WT_F05.07938.07938.2 0.000105 16-Sep R.TYSQDC[160.03]SFK[136.11].N "sp|Q86U86|PB1_HUMAN,tr|H0Y5B5|H0Y5B5_HUMAN,tr|E7EVG2|E7EVG2_HUMAN" 3 1142.4794 1.57 60898 7938 2 1142.479601 572.247 Protein polybromo-1 OS=Homo sapiens OX=9606 GN=PBRM1 PE=1 SV=1 5.5 1864 - 918815 - - - 0.1978 - 1.413 0.563 - 211.4 1 2 0 0.0002 9 0 0 0 2.77E+07 1.77E+07 - - - 4.1994 0.9997 221125_WJC_METTL3_EV_vs_WT_F05.07942.07942.2 0.0002 18-Sep K.IAPPETPDSK.V sp|Q9NZI8|IF2B1_HUMAN 1 1053.5342 1.82 60901 7942 2 1053.534567 527.7744 Insulin-like growth factor 2 mRNA-binding protein 1 OS=Homo sapiens OX=9606 GN=IGF2BP1 PE=1 SV=2 4.37 1864.5 - 1.22E+07 - - - 0.3104 - 1.596 0.453 - 326.6 1 2 0 0.0003 10 0 0 0 4.20E+08 2.31E+08 - - - 3.6917 0.9961 221125_WJC_METTL3_EV_vs_WT_F05.07944.07944.2 9.34E-05 16-Dec R.VAQILKEPK.V "sp|P48047|ATPO_HUMAN,tr|H7C0C1|H7C0C1_HUMAN,tr|A0A494C0K9|A0A494C0K9_HUMAN" 3 1024.6281 1 60902 7944 2 1024.62836 513.3213 "ATP synthase subunit O, mitochondrial OS=Homo sapiens OX=9606 GN=ATP5PO PE=1 SV=1" 8.56 1864.7 - 2.00E+06 - - - 0.2723 - 2.389 0.256 - 634.7 1 2 1 0.0003 9 0 0 0 4.12E+07 4.13E+07 - - - 3.4512 0.9989 221125_WJC_METTL3_EV_vs_WT_F05.07945.07945.2 0.00629 14-Oct K.RFEGLTQR.G sp|Q9Y2H1|ST38L_HUMAN 1 1005.5356 1.03 60903 7945 2 1005.536382 503.7751 Serine\threonine-protein kinase 38-like OS=Homo sapiens OX=9606 GN=STK38L PE=1 SV=3 9.6 1864.8 - 2.07E+06 - - - 0.7996 - 1.777 0.226 - 212.3 1 2 0 0.0008 8 0 0 0 8.32E+07 8.10E+07 - - - 2.4439 0.9943 221125_WJC_METTL3_EV_vs_WT_F05.07946.07946.2 0.71 12-Aug K.HGQFTLR[166.11].D "sp|P61011|SRP54_HUMAN,tr|A0A7P0PJI2|A0A7P0PJI2_HUMAN,tr|G3V4F7|G3V4F7_HUMAN,tr|G3V480|G3V480_HUMAN,tr|A0A7I2V5K0|A0A7I2V5K0_HUMAN" 5 867.4591 1.12 60904 7946 2 867.457953 434.7368 Signal recognition particle 54 kDa protein OS=Homo sapiens OX=9606 GN=SRP54 PE=1 SV=1 9.76 1864.9 - 981883 - - - -1.2704 - 1.385 0.157 - 171.2 1 2 0 -0.0011 7 0 0 0 1.73E+07 1.54E+07 - - - 1.2323 0.9987 221125_WJC_METTL3_EV_vs_WT_F05.07951.07951.2 0.00086 18-Aug K.SLQEEEPC[160.03]PR[166.11].F "sp|Q9UL63|MKLN1_HUMAN,tr|C9J7E8|C9J7E8_HUMAN" 2 1253.5586 0.86 60907 7951 2 1253.560556 627.7866 Muskelin OS=Homo sapiens OX=9606 GN=MKLN1 PE=1 SV=2 4.25 1865.6 - 226585 - - - 1.5835 - 1.399 0.365 - 165.7 1 2 0 0.002 10 0 0 0 7.41E+06 8.63E+06 - - - 2.6735 0.9993 221125_WJC_METTL3_EV_vs_WT_F05.07952.07952.2 0.0228 18-Aug K.YNPSEEEYEK[136.11].A sp|O00443|P3C2A_HUMAN 1 1294.5445 1.52 60908 7952 2 1294.541915 648.2795 Phosphatidylinositol 4-phosphate 3-kinase C2 domain-containing subunit alpha OS=Homo sapiens OX=9606 GN=PIK3C2A PE=1 SV=2 4.09 1865.7 - 305668 - - - -1.9791 - 1.167 0.543 - 164.7 1 2 0 -0.0026 10 0 0 0 1.05E+07 6.90E+06 - - - 3.4819 0.9994 221125_WJC_METTL3_EV_vs_WT_F05.07954.07954.3 0.00498 Sep-48 R.VAASLHNTPMGAR.R sp|Q9ULW3|ABT1_HUMAN 1 1323.6718 1.18 60910 7954 3 1323.671199 442.2312 Activator of basal transcription 1 OS=Homo sapiens OX=9606 GN=ABT1 PE=1 SV=1 9.73 1865.9 - 635592 - - - -0.4193 - 1.851 0.308 - 88.2 1 2 0 -0.0006 13 0 0 0 2.16E+07 1.83E+07 - - - 3.6432 0.9999 221125_WJC_METTL3_EV_vs_WT_F05.07955.07955.2 0.000156 20-Nov K.TTEENQELVTR.W "sp|Q676U5|A16L1_HUMAN,tr|E7EVC7|E7EVC7_HUMAN" 2 1318.6365 2.52 60911 7955 2 1318.63587 660.3255 Autophagy-related protein 16-1 OS=Homo sapiens OX=9606 GN=ATG16L1 PE=1 SV=2 4.25 1866 - 449789 - - - -0.458 - 2.565 0.522 - 723.1 1 2 0 -0.0006 11 0 0 0 1.32E+07 5.26E+06 - - - 5.4445 0.9997 221125_WJC_METTL3_EV_vs_WT_F05.07958.07958.3 0.00679 Nov-36 K.LNVEAVNTHR.D "sp|O60825|F262_HUMAN,sp|P16118|F261_HUMAN,tr|I1Z9G3|I1Z9G3_HUMAN,tr|Q4VBA9|Q4VBA9_HUMAN" 4 1151.6047 0.66 60912 7958 3 1151.603339 384.8755 "6-phosphofructo-2-kinase\fructose-2,6-bisphosphatase 2 OS=Homo sapiens OX=9606 GN=PFKFB2 PE=1 SV=2" 6.75 1866.4 - 1.86E+06 - - - -1.1992 - 2.188 0.322 - 154.7 1 2 0 -0.0014 10 0 0 0 3.54E+07 5.35E+07 - - - 4.4163 0.9997 221125_WJC_METTL3_EV_vs_WT_F05.07965.07965.2 4.84E-05 18-Aug K.YNPSEEEYEK.A sp|O00443|P3C2A_HUMAN 1 1286.5303 1.52 60917 7965 2 1286.528453 644.2724 Phosphatidylinositol 4-phosphate 3-kinase C2 domain-containing subunit alpha OS=Homo sapiens OX=9606 GN=PIK3C2A PE=1 SV=2 4.09 1867.2 - 617231 - - - -1.4178 - 1.546 0.507 - 170 1 2 0 -0.0018 10 0 0 0 1.05E+07 6.90E+06 - - - 4.0012 0.9813 221125_WJC_METTL3_EV_vs_WT_F05.07966.07966.2 0.843 12-Aug K.SQDFYEK.E sp|Q8N183|NDUF2_HUMAN 1 915.3974 3.08 60918 7966 2 915.396406 458.706 NADH dehydrogenase [ubiquinone] 1 alpha subcomplex assembly factor 2 OS=Homo sapiens OX=9606 GN=NDUFAF2 PE=1 SV=1 4.37 1867.3 - 609150 - - - -1.099 - 1.194 0.101 - 261.3 1 2 0 -0.001 7 0 0 0 1.09E+07 3.53E+06 - - - 0.3485 0.9998 221125_WJC_METTL3_EV_vs_WT_F05.07968.07968.2 2.83E-06 20-Nov R.SAEC[160.03]IDEAAER.L sp|Q8IYS1|P20D2_HUMAN 1 1249.5245 1.35 60920 7968 2 1249.52191 625.7695 Xaa-Arg dipeptidase OS=Homo sapiens OX=9606 GN=PM20D2 PE=1 SV=2 4 1867.6 - 295088 - - - -2.0576 - 2.248 0.6 - 320.9 1 2 0 -0.0026 11 0 0 0 5.69E+06 4.20E+06 - - - 5.6631 0.9991 221125_WJC_METTL3_EV_vs_WT_F05.07969.07969.2 0.000993 24-Oct R.LGDPGPQEAQTPR.S sp|Q5JXC2|MIIP_HUMAN 1 1364.6684 3.96 60921 7969 2 1364.664366 683.3415 Migration and invasion-inhibitory protein OS=Homo sapiens OX=9606 GN=MIIP PE=1 SV=3 4.37 1867.8 - 153412 - - - -2.9868 - 2.001 0.437 - 260.3 1 2 0 -0.0041 13 0 0 0 5.53E+06 1.39E+06 - - - 4.0477 0.9975 221125_WJC_METTL3_EV_vs_WT_F05.07970.07970.2 0.00311 24-May K.IIEDC[160.03]SNSEDTIK[136.11].L sp|O00507|USP9Y_HUMAN 1 1530.6963 0.77 60922 7970 2 1530.694401 766.3554 Probable ubiquitin carboxyl-terminal hydrolase FAF-Y OS=Homo sapiens OX=9606 GN=USP9Y PE=2 SV=2 3.92 1867.9 - 148399 - - - -1.2432 - 1.039 0.367 - 51.1 1 2 0 -0.0019 13 0 0 0 1.32E+06 1.71E+06 - - - 1.8493 0.9996 221125_WJC_METTL3_EV_vs_WT_F05.07972.07972.2 0.00374 20-Oct K.IANPVEGSSGR[166.11].Q sp|Q15365|PCBP1_HUMAN 1 1095.5548 0.96 60923 7972 2 1095.554388 548.7847 Poly(rC)-binding protein 1 OS=Homo sapiens OX=9606 GN=PCBP1 PE=1 SV=2 6 1868.1 - 3.07E+06 - - - -0.3815 - 2.104 0.299 - 375.8 1 2 0 -0.0004 11 0 0 0 1.26E+08 1.30E+08 - - - 3.2615 0.9332 221125_WJC_METTL3_EV_vs_WT_F05.07974.07974.2 0.569 14-Sep P.LPLSSQHR[166.11].G "sp|P43243|MATR3_HUMAN,tr|A8MXP9|A8MXP9_HUMAN,tr|D6R991|D6R991_HUMAN,tr|A0A0R4J2E8|A0A0R4J2E8_HUMAN,tr|D6R8Z5|D6R8Z5_HUMAN,tr|D6REM6|D6REM6_HUMAN" 6 946.5224 1.19 60924 7974 2 946.522502 474.2685 Matrin-3 OS=Homo sapiens OX=9606 GN=MATR3 PE=1 SV=2 9.76 1868.3 - 2.02E+06 - - - 0.1247 - 1.719 0.21 - 369.7 1 1 0 0.0001 8 0 0 0 4.06E+08 3.41E+08 - - - 2.2259 0.9995 221125_WJC_METTL3_EV_vs_WT_F05.07982.07982.2 0.00871 18-Aug R.GPLPLSSQHR.G "sp|P43243|MATR3_HUMAN,tr|A8MXP9|A8MXP9_HUMAN,tr|D6R991|D6R991_HUMAN,tr|A0A0R4J2E8|A0A0R4J2E8_HUMAN,tr|D6R8Z5|D6R8Z5_HUMAN,tr|D6REM6|D6REM6_HUMAN" 6 1090.5883 1.35 60930 7982 2 1090.587932 546.3014 Matrin-3 OS=Homo sapiens OX=9606 GN=MATR3 PE=1 SV=2 9.76 1869.3 - 1.13E+07 - - - -0.3759 - 1.552 0.362 - 198.7 1 2 0 -0.0004 10 0 0 0 1.68E+09 1.25E+09 - - - 2.9415 0.9992 221125_WJC_METTL3_EV_vs_WT_F05.07983.07983.2 0.00256 16-Aug K.ANNLSSLSK.K sp|O75396|SC22B_HUMAN 1 932.4927 1.32 60931 7983 2 932.494588 467.2536 Vesicle-trafficking protein SEC22b OS=Homo sapiens OX=9606 GN=SEC22B PE=1 SV=5 8.8 1869.3 - 2.77E+06 - - - 2.014 - 1.475 0.441 - 184.5 1 2 0 0.0019 9 0 0 0 7.86E+07 5.96E+07 - - - 3.422 0.9884 221125_WJC_METTL3_EV_vs_WT_F05.07984.07984.2 0.316 14-Jun K.VISELNGK[136.11].N "sp|P05387|RLA2_HUMAN,tr|H0YDD8|H0YDD8_HUMAN" 2 866.4953 1.46 60932 7984 2 866.494727 434.2549 60S acidic ribosomal protein P2 OS=Homo sapiens OX=9606 GN=RPLP2 PE=1 SV=1 5.97 1869.4 - 733923 - - - -0.6417 - 1.066 0.179 - 106.3 1 2 0 -0.0006 8 0 0 0 2.00E+07 1.37E+07 - - - 0.5557 1 221125_WJC_METTL3_EV_vs_WT_F05.07987.07987.2 2.95E-07 26-Dec R.SYAASASAAPAEPR[166.11].Y sp|P20719|HXA5_HUMAN 1 1357.6502 1.67 60935 7987 2 1357.650226 679.8324 Homeobox protein Hox-A5 OS=Homo sapiens OX=9606 GN=HOXA5 PE=1 SV=2 5.72 1869.8 - 226870 - - - 0.0464 - 2.598 0.589 - 358.3 1 2 0 0.0001 14 0 0 0 1.89E+07 1.13E+07 - - - 5.7872 0.9989 221125_WJC_METTL3_EV_vs_WT_F05.07990.07990.2 0.0457 14-Jul K.VISELNGK.N "sp|P05387|RLA2_HUMAN,tr|H0YDD8|H0YDD8_HUMAN" 2 858.4811 1.46 60936 7990 2 858.480578 430.2478 60S acidic ribosomal protein P2 OS=Homo sapiens OX=9606 GN=RPLP2 PE=1 SV=1 5.97 1870.2 - 1.23E+06 - - - -0.5882 - 1.331 0.326 - 148.4 1 2 0 -0.0005 8 0 0 0 2.00E+07 1.37E+07 - - - 2.311 0.9996 221125_WJC_METTL3_EV_vs_WT_F05.07992.07992.2 0.0019 14-Aug K.QQEIVVSR.G "sp|Q15393|SF3B3_HUMAN,tr|I3L4G7|I3L4G7_HUMAN" 2 957.5243 0.91 60938 7992 2 957.523924 479.7694 Splicing factor 3B subunit 3 OS=Homo sapiens OX=9606 GN=SF3B3 PE=1 SV=4 6 1870.4 - 1.17E+06 - - - -0.4386 - 1.669 0.359 - 404.1 1 2 0 -0.0004 8 0 0 0 1.89E+07 2.08E+07 - - - 3.2373 0.9998 221125_WJC_METTL3_EV_vs_WT_F05.07994.07994.2 7.59E-05 20-Aug R.TGNGPMSVC[160.03]GR.C "sp|O95793|STAU1_HUMAN,tr|Q5JW30|Q5JW30_HUMAN" 2 1134.491 1.29 60940 7994 2 1134.490184 568.2528 Double-stranded RNA-binding protein Staufen homolog 1 OS=Homo sapiens OX=9606 GN=STAU1 PE=1 SV=2 7.91 1870.6 - 3.52E+06 - - - -0.7298 - 1.608 0.527 - 181 1 2 0 -0.0008 11 0 0 0 6.21E+07 4.83E+07 - - - 4.2181 0.9988 221125_WJC_METTL3_EV_vs_WT_F05.07996.07996.3 0.009 Oct-36 R.AVAILC[160.03]NHQR[166.11].A "sp|P11387|TOP1_HUMAN,tr|A0A7P0T852|A0A7P0T852_HUMAN" 2 1190.6218 1.11 60942 7996 3 1190.625232 397.8812 DNA topoisomerase 1 OS=Homo sapiens OX=9606 GN=TOP1 PE=1 SV=2 8.3 1870.9 - 475162 - - - 2.8985 - 2.177 0.3 - 106.2 1 2 0 0.0035 10 0 0 0 1.11E+07 9.96E+06 - - - 4.1557 0.9996 221125_WJC_METTL3_EV_vs_WT_F05.08000.08000.2 0.00222 14-Aug K.DIIHDPGR.G "sp|P62917|RL8_HUMAN,tr|G3V1A1|G3V1A1_HUMAN,tr|E9PKZ0|E9PKZ0_HUMAN,tr|E9PKU4|E9PKU4_HUMAN" 4 921.4668 1.08 60944 8000 2 921.46571 461.7407 60S ribosomal protein L8 OS=Homo sapiens OX=9606 GN=RPL8 PE=1 SV=2 5.21 1871.4 - 2.72E+06 - - - -1.2144 - 1.676 0.417 - 244.4 1 2 0 -0.0011 8 0 0 0 5.46E+07 5.04E+07 - - - 3.6781 0.9999 221125_WJC_METTL3_EV_vs_WT_F05.08002.08002.2 0.000342 14-Oct K.NDYDQLQK.A sp|P15924|DESP_HUMAN 1 1022.4669 7.36 60946 8002 2 1022.46651 512.2407 Desmoplakin OS=Homo sapiens OX=9606 GN=DSP PE=1 SV=3 4.21 1871.7 - 1.44E+06 - - - -0.3707 - 2.023 0.484 - 559.2 1 2 0 -0.0004 8 0 0 0 1.62E+08 2.20E+07 - - - 4.7407 0.9997 221125_WJC_METTL3_EV_vs_WT_F05.08007.08007.2 0.000472 18-Sep K.ESDLNGAQIK.L "sp|P20700|LMNB1_HUMAN,tr|A0A0D9SFY5|A0A0D9SFY5_HUMAN,tr|E9PBF6|E9PBF6_HUMAN,tr|A0A0D9SFE5|A0A0D9SFE5_HUMAN" 4 1073.5353 1.58 60949 8007 2 1073.535513 537.7749 Lamin-B1 OS=Homo sapiens OX=9606 GN=LMNB1 PE=1 SV=2 4.37 1872.3 - 6.66E+06 - - - 0.1956 - 1.957 0.37 - 277.3 1 2 0 0.0002 10 0 0 0 1.79E+08 1.13E+08 - - - 3.6479 0.9999 221125_WJC_METTL3_EV_vs_WT_F05.08008.08008.2 4.15E-09 20-Oct R.GPDELEGPDSK[136.11].L sp|P48634|PRC2A_HUMAN 1 1150.5233 0.82 60950 8008 2 1150.523759 576.269 Protein PRRC2A OS=Homo sapiens OX=9606 GN=PRRC2A PE=1 SV=3 3.92 1872.4 - 779455 - - - 0.3572 - 2.495 0.534 - 400.4 1 2 0 0.0004 11 0 0 0 1.57E+07 1.92E+07 - - - 5.4584 0.9746 221125_WJC_METTL3_EV_vs_WT_F05.08009.08009.2 0.225 16-May R.R[166.11]AIYQATYR[166.11].D sp|P28074|PSB5_HUMAN 1 1160.6205 0.28 60951 8009 2 1160.619484 581.3175 Proteasome subunit beta type-5 OS=Homo sapiens OX=9606 GN=PSMB5 PE=1 SV=3 9.99 1872.6 - 507627 - - - -0.903 - 1.31 0.126 - 37.7 30 2 0 -0.001 9 0 0 0 1.02E+07 3.59E+07 - - - 0.0927 0.9989 221125_WJC_METTL3_EV_vs_WT_F05.08010.08010.2 0.000603 18-Jul R.SYVDPSTDER[166.11].L "sp|Q15149|PLEC_HUMAN,tr|H0YDN1|H0YDN1_HUMAN" 2 1177.5127 2.68 60952 8010 2 1177.510467 589.7636 Plectin OS=Homo sapiens OX=9606 GN=PLEC PE=1 SV=3 4.03 1872.7 - 361492 - - - -1.8683 - 1.331 0.419 - 156 1 2 0 -0.0022 10 0 0 0 4.49E+07 1.67E+07 - - - 2.9332 0.9997 221125_WJC_METTL3_EV_vs_WT_F05.08011.08011.2 0.000171 18-Sep R.SYVDPSTDER.L "sp|Q15149|PLEC_HUMAN,tr|H0YDN1|H0YDN1_HUMAN" 2 1167.5044 2.68 60953 8011 2 1167.501929 584.7595 Plectin OS=Homo sapiens OX=9606 GN=PLEC PE=1 SV=3 4.03 1872.8 - 350797 - - - -2.1139 - 1.775 0.527 - 251.5 1 2 0 -0.0025 10 0 0 0 4.49E+07 1.67E+07 - - - 4.5343 0.996 221125_WJC_METTL3_EV_vs_WT_F05.08014.08014.2 0.237 18-Aug R.AAQVMGPPDR.C sp|Q96I24|FUBP3_HUMAN 1 1040.5073 0.54 60954 8014 2 1040.505256 521.2609 Far upstream element-binding protein 3 OS=Homo sapiens OX=9606 GN=FUBP3 PE=1 SV=2 5.88 1873.2 - 396904 - - - -1.9779 - 1.463 0.236 - 224.2 1 2 0 -0.0021 10 0 0 0 1.49E+07 2.78E+07 - - - 1.8455 0.9996 221125_WJC_METTL3_EV_vs_WT_F05.08016.08016.3 0.000413 Nov-44 K.QR[166.11]YPDGIISK[136.11]PK[136.11].N sp|Q86U44|MTA70_HUMAN 1 1426.8143 0.001 60956 8016 3 1426.813308 476.612 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 9.7 1873.4 - 1.12E+06 - - - -0.6735 - 2.173 0.414 - 177 1 2 1 -0.001 12 0 0 0 0.00E+00 3.26E+07 - - - 5.3067 0.9982 221125_WJC_METTL3_EV_vs_WT_F05.08017.08017.2 0.0301 16-Jul K.EGIPPDQQR[166.11].L "sp|P62979|RS27A_HUMAN,sp|P0CG48|UBC_HUMAN,sp|P0CG48|UBC_HUMAN,sp|P0CG48|UBC_HUMAN,sp|P0CG48|UBC_HUMAN,sp|P0CG48|UBC_HUMAN,sp|P0CG48|UBC_HUMAN,sp|P0CG48|UBC_HUMAN,sp|P0CG48|UBC_HUMAN,sp|P0CG48|UBC_HUMAN,sp|P0CG47|UBB_HUMAN,sp|P0CG47|UBB_HUMAN,sp|P0CG47|UBB_HUMAN,sp|P62987|RL40_HUMAN,tr|F5H388|F5H388_HUMAN,tr|F5H388|F5H388_HUMAN,tr|F5GYU3|F5GYU3_HUMAN,tr|F5GYU3|F5GYU3_HUMAN,tr|B4DV12|B4DV12_HUMAN,tr|B4DV12|B4DV12_HUMAN,tr|J3QSA3|J3QSA3_HUMAN,tr|Q5PY61|Q5PY61_HUMAN,tr|Q5PY61|Q5PY61_HUMAN,tr|Q5PY61|Q5PY61_HUMAN,tr|F5H2Z3|F5H2Z3_HUMAN,tr|F5H2Z3|F5H2Z3_HUMAN,tr|M0R2S1|M0R2S1_HUMAN,tr|J3QS39|J3QS39_HUMAN,tr|J3QTR3|J3QTR3_HUMAN,tr|Q96C32|Q96C32_HUMAN,tr|Q96C32|Q96C32_HUMAN,tr|Q96C32|Q96C32_HUMAN,tr|Q96C32|Q96C32_HUMAN,tr|M0R1V7|M0R1V7_HUMAN,tr|F5H747|F5H747_HUMAN,tr|F5H747|F5H747_HUMAN,tr|F5GXK7|F5GXK7_HUMAN,tr|F5GXK7|F5GXK7_HUMAN,tr|M0R1M6|M0R1M6_HUMAN,tr|F5H6Q2|F5H6Q2_HUMAN,tr|F5H6Q2|F5H6Q2_HUMAN,tr|F5GZ39|F5GZ39_HUMAN,tr|J3QKN0|J3QKN0_HUMAN,tr|J3QKN0|J3QKN0_HUMAN,tr|J3QKN0|J3QKN0_HUMAN,tr|F5H265|F5H265_HUMAN,tr|F5H265|F5H265_HUMAN,tr|A0A2R8Y422|A0A2R8Y422_HUMAN" 48 1048.5177 0.74 60957 8017 2 1048.518345 525.2661 Ubiquitin-40S ribosomal protein S27a OS=Homo sapiens OX=9606 GN=RPS27A PE=1 SV=2 4.37 1873.6 - 744450 - - - 0.6218 - 1.502 0.238 - 177.9 1 2 0 0.0007 9 0 0 0 3.28E+07 4.42E+07 - - - 1.9756 1 221125_WJC_METTL3_EV_vs_WT_F05.08021.08021.2 1.72E-06 14/24 K.AVESIQAEDESAK.L "sp|Q7L5Y9|MAEA_HUMAN,tr|D6REW7|D6REW7_HUMAN,tr|B4DVN3|B4DVN3_HUMAN,tr|D6RIB6|D6RIB6_HUMAN,tr|B4DQT1|B4DQT1_HUMAN,tr|E7ESC7|E7ESC7_HUMAN,tr|D6RID6|D6RID6_HUMAN,tr|D6RDW4|D6RDW4_HUMAN" 8 1375.6467 2.91 60960 8021 2 1375.642843 688.8306 E3 ubiquitin-protein transferase MAEA OS=Homo sapiens OX=9606 GN=MAEA PE=1 SV=1 4 1874 - 398629 - - - -2.8067 - 2.768 0.665 - 674.6 1 2 0 -0.0039 13 0 0 0 7.81E+06 2.68E+06 - - - 6.5645 0.9846 221125_WJC_METTL3_EV_vs_WT_F05.08023.08023.2 0.108 12-Jul R.FRDPDLR.Q "sp|O43251|RFOX2_HUMAN,sp|Q9NWB1|RFOX1_HUMAN,sp|A6NFN3|RFOX3_HUMAN,tr|A0A6Q8PGE0|A0A6Q8PGE0_HUMAN,tr|A0A6Q8PH77|A0A6Q8PH77_HUMAN,tr|A0A286YEU2|A0A286YEU2_HUMAN,tr|A0A087X2B1|A0A087X2B1_HUMAN,tr|F8VR27|F8VR27_HUMAN,tr|B7Z1U7|B7Z1U7_HUMAN,tr|B0QYY6|B0QYY6_HUMAN,tr|B0QYV1|B0QYV1_HUMAN,tr|A0A6Q8PHA3|A0A6Q8PHA3_HUMAN,tr|A0A3B3ITL7|A0A3B3ITL7_HUMAN,tr|F8VZY7|F8VZY7_HUMAN,tr|B0QYY4|B0QYY4_HUMAN,tr|J3KNW3|J3KNW3_HUMAN,tr|F8VZG9|F8VZG9_HUMAN,tr|J3QRF4|J3QRF4_HUMAN,tr|F8VRS4|F8VRS4_HUMAN,tr|A0A6Q8PFM4|A0A6Q8PFM4_HUMAN,tr|S4R469|S4R469_HUMAN,tr|A0A804HKG7|A0A804HKG7_HUMAN,tr|A0A0G2JRA5|A0A0G2JRA5_HUMAN,tr|A0A804HJM2|A0A804HJM2_HUMAN,tr|J3QQZ2|J3QQZ2_HUMAN,tr|I3L1D4|I3L1D4_HUMAN,tr|B0QYY7|B0QYY7_HUMAN,tr|A0A0G2JSB3|A0A0G2JSB3_HUMAN" 28 917.4719 1.64 60961 8023 2 917.471003 459.7432 RNA binding protein fox-1 homolog 2 OS=Homo sapiens OX=9606 GN=RBFOX2 PE=1 SV=3 5.96 1874.2 - 1.88E+06 - - - -0.994 - 1.425 0.281 - 230 1 2 1 -0.0009 7 0 0 0 5.11E+07 3.11E+07 - - - 2.2384 0.9998 221125_WJC_METTL3_EV_vs_WT_F05.08024.08024.2 0.0028 20-Oct K.AAQEQVLNASR.A sp|Q99543|DNJC2_HUMAN 1 1185.6102 0.93 60962 8024 2 1185.612021 593.8124 DnaJ homolog subfamily C member 2 OS=Homo sapiens OX=9606 GN=DNAJC2 PE=1 SV=4 6.05 1874.4 - 624345 - - - 1.5368 - 2.479 0.427 - 471.7 1 2 0 0.0018 11 0 0 0 1.16E+07 1.24E+07 - - - 4.6502 0.7812 221125_WJC_METTL3_EV_vs_WT_F05.08028.08028.2 0.253 22-Jun F.ALSTGDPSQPVR[166.11].L sp|Q9BY32|ITPA_HUMAN 1 1236.6338 6.25 60966 8028 2 1236.634373 619.3242 Inosine triphosphate pyrophosphatase OS=Homo sapiens OX=9606 GN=ITPA PE=1 SV=2 5.88 1874.9 - 158936 - - - 0.4755 - 1.306 0.199 - 95.4 1 1 0 0.0006 12 0 0 0 2.58E+07 4.12E+06 - - - 1.2131 0.9084 221125_WJC_METTL3_EV_vs_WT_F05.08030.08030.2 0.0808 14-Jul P.LPLSSQHR.G "sp|P43243|MATR3_HUMAN,tr|A8MXP9|A8MXP9_HUMAN,tr|D6R991|D6R991_HUMAN,tr|A0A0R4J2E8|A0A0R4J2E8_HUMAN,tr|D6R8Z5|D6R8Z5_HUMAN,tr|D6REM6|D6REM6_HUMAN" 6 936.5141 1.12 60967 8030 2 936.513875 469.2643 Matrin-3 OS=Homo sapiens OX=9606 GN=MATR3 PE=1 SV=2 9.76 1875.1 - 4.25E+06 - - - -0.2552 - 1.333 0.274 - 180.8 1 1 0 -0.0002 8 0 0 0 3.35E+08 3.00E+08 - - - 1.9316 0.9998 221125_WJC_METTL3_EV_vs_WT_F05.08034.08034.2 8.19E-05 22-Nov R.TPSNGAEGLTPR[166.11].S sp|Q99459|CDC5L_HUMAN 1 1208.6025 0.5 60970 8034 2 1208.600407 605.3085 Cell division cycle 5-like protein OS=Homo sapiens OX=9606 GN=CDC5L PE=1 SV=2 5.66 1875.5 - 2.31E+06 - - - -1.7193 - 2.386 0.474 - 533.2 1 2 0 -0.0021 12 0 0 0 2.94E+07 5.89E+07 - - - 4.8294 0.8477 221125_WJC_METTL3_EV_vs_WT_F05.08035.08035.2 1.13 14-Apr R.NTNPNFVR[166.11].C "sp|P35580|MYH10_HUMAN,sp|P35579|MYH9_HUMAN" 2 970.486 0.91 60971 8035 2 970.484086 486.2503 Myosin-10 OS=Homo sapiens OX=9606 GN=MYH10 PE=1 SV=3 9.75 1875.6 - 2.46E+06 - - - -1.9701 - 1.13 0.072 - 34.3 32 2 0 -0.0019 8 0 0 0 5.28E+07 5.79E+07 - - - -0.7316 0.9995 221125_WJC_METTL3_EV_vs_WT_F05.08042.08042.2 0.00201 16-Jul R.RPSTYGIPR.L "sp|P78347|GTF2I_HUMAN,tr|A0A494C0Q7|A0A494C0Q7_HUMAN,tr|A0A494C1K3|A0A494C1K3_HUMAN" 3 1045.5669 1.59 60976 8042 2 1045.566653 523.7907 General transcription factor II-I OS=Homo sapiens OX=9606 GN=GTF2I PE=1 SV=2 10.84 1876.5 - 1.63E+06 - - - -0.2152 - 1.852 0.289 - 90.5 1 2 0 -0.0002 9 0 0 0 5.48E+08 3.45E+08 - - - 2.9584 0.9993 221125_WJC_METTL3_EV_vs_WT_F05.08043.08043.2 0.000647 16-Sep K.ANEEIAQVR.T "sp|O75410|TACC1_HUMAN,sp|Q9Y6A5|TACC3_HUMAN,tr|E7EVI4|E7EVI4_HUMAN,tr|B4E3H6|B4E3H6_HUMAN,tr|A0A087WUE2|A0A087WUE2_HUMAN,tr|H0YAY0|H0YAY0_HUMAN,tr|H0YBT8|H0YBT8_HUMAN,tr|A0A494BZT8|A0A494BZT8_HUMAN,tr|E7ET87|E7ET87_HUMAN" 9 1028.5251 29.35 60977 8043 2 1028.523101 515.2698 Transforming acidic coiled-coil-containing protein 1 OS=Homo sapiens OX=9606 GN=TACC1 PE=1 SV=2 4.53 1876.6 - 738926 - - - -1.9173 - 1.885 0.351 - 361.5 1 2 0 -0.002 9 0 0 0 3.46E+07 1.18E+06 - - - 3.4669 0.9992 221125_WJC_METTL3_EV_vs_WT_F05.08049.08049.2 0.00352 16-Oct R.R[166.11]PSTYGIPR[166.11].L "sp|P78347|GTF2I_HUMAN,tr|A0A494C0Q7|A0A494C0Q7_HUMAN,tr|A0A494C1K3|A0A494C1K3_HUMAN" 3 1065.5834 1.56 60981 8049 2 1065.584209 533.799 General transcription factor II-I OS=Homo sapiens OX=9606 GN=GTF2I PE=1 SV=2 10.84 1877.3 - 1.72E+06 - - - 0.7423 - 1.541 0.329 - 189.6 1 2 0 0.0008 9 0 0 0 5.39E+08 3.45E+08 - - - 2.7218 0.9968 221125_WJC_METTL3_EV_vs_WT_F05.08050.08050.2 0.00984 20-Jun K.C[160.03]PAPC[160.03]QTTYVK.C sp|Q5T750|XP32_HUMAN 1 1323.5951 8.98 60982 8050 2 1323.599226 662.8048 Skin-specific protein 32 OS=Homo sapiens OX=9606 GN=XP32 PE=1 SV=1 8.05 1877.4 - 312334 - - - 3.0848 - 1.315 0.403 - 45.7 1 2 0 0.0041 11 0 0 0 6.88E+07 7.66E+06 - - - 2.7571 0.9968 221125_WJC_METTL3_EV_vs_WT_F05.08057.08057.2 0.00487 18-Aug R.IAELSEDDQK[136.11].L sp|Q9BZE4|GTPB4_HUMAN 1 1154.5546 11.67 60986 8057 2 1154.558532 578.2846 GTP-binding protein 4 OS=Homo sapiens OX=9606 GN=GTPBP4 PE=1 SV=3 3.92 1878.3 - 609427 - - - 3.3641 - 1.888 0.291 - 193 1 2 0 0.0039 10 0 0 0 4.76E+08 4.08E+07 - - - 2.963 0.9998 221125_WJC_METTL3_EV_vs_WT_F05.08061.08061.2 0.000154 18-Sep K.AGFAGDDAPR[166.11].A "sp|Q6S8J3|POTEE_HUMAN,sp|P63261|ACTG_HUMAN,sp|P68133|ACTS_HUMAN,sp|P62736|ACTA_HUMAN,sp|P68032|ACTC_HUMAN,sp|P60709|ACTB_HUMAN,sp|P63267|ACTH_HUMAN,sp|A5A3E0|POTEF_HUMAN,sp|P0CG38|POTEI_HUMAN,sp|P0CG39|POTEJ_HUMAN,tr|A0A804GS07|A0A804GS07_HUMAN,tr|I3L3I0|I3L3I0_HUMAN,tr|G5E9R0|G5E9R0_HUMAN,tr|E7EVS6|E7EVS6_HUMAN,tr|A0A6Q8PGD7|A0A6Q8PGD7_HUMAN,tr|B8ZZJ2|B8ZZJ2_HUMAN,tr|J3KT65|J3KT65_HUMAN,tr|I3L3R2|I3L3R2_HUMAN,tr|K7EM38|K7EM38_HUMAN,tr|F6QUT6|F6QUT6_HUMAN,tr|C9JTX5|C9JTX5_HUMAN,tr|A0A6Q8PH58|A0A6Q8PH58_HUMAN,tr|F6UVQ4|F6UVQ4_HUMAN,tr|F8WB63|F8WB63_HUMAN,tr|I3L1U9|I3L1U9_HUMAN,tr|A0A2R8Y793|A0A2R8Y793_HUMAN,tr|I3L4N8|I3L4N8_HUMAN,tr|C9JUM1|C9JUM1_HUMAN,tr|F8WCH0|F8WCH0_HUMAN,tr|C9JZR7|C9JZR7_HUMAN,tr|C9JFL5|C9JFL5_HUMAN,tr|A0A2R8YGF8|A0A2R8YGF8_HUMAN,tr|A6NL76|A6NL76_HUMAN,tr|A0A7P0TBL1|A0A7P0TBL1_HUMAN" 34 985.4493 0.91 60988 8061 2 985.449089 493.7319 POTE ankyrin domain family member E OS=Homo sapiens OX=9606 GN=POTEE PE=2 SV=3 4.21 1878.8 - 537180 - - - -0.1928 - 1.915 0.486 - 213.8 1 2 0 -0.0002 10 0 0 0 3.20E+07 3.52E+07 - - - 4.4441 0.9991 221125_WJC_METTL3_EV_vs_WT_F05.08062.08062.3 0.00155 Aug-36 K.YEELQQTAGR.H "sp|P13647|K2C5_HUMAN,tr|H0YI76|H0YI76_HUMAN,tr|H0YIN9|H0YIN9_HUMAN" 3 1193.5677 30.76 60989 8062 3 1193.565572 398.8632 "Keratin, type II cytoskeletal 5 OS=Homo sapiens OX=9606 GN=KRT5 PE=1 SV=3" 4.53 1878.9 - 477955 - - - -1.7544 - 1.922 0.289 - 114.6 1 2 0 -0.0021 10 0 0 0 4.16E+07 1.35E+06 - - - 3.6696 0.9974 221125_WJC_METTL3_EV_vs_WT_F05.08063.08063.2 2.96E-08 24-Sep R.TAPGMGDQSGC[160.03]YR.C "sp|Q9BWF3|RBM4_HUMAN,sp|Q9BQ04|RBM4B_HUMAN,tr|E9PB51|E9PB51_HUMAN" 3 1398.5656 2.72 60990 8063 2 1398.557772 700.2901 RNA-binding protein 4 OS=Homo sapiens OX=9606 GN=RBM4 PE=1 SV=1 5.5 1879 - 168206 - - - -5.6215 - 1.823 0.675 - 203.1 1 2 0 -0.0079 13 0 0 0 7.89E+06 2.90E+06 - - - 5.5652 0.9997 221125_WJC_METTL3_EV_vs_WT_F05.08068.08068.2 0.000293 16-Sep K.TQSLPVTEK[136.11].V sp|Q9NQW6|ANLN_HUMAN 1 1009.5535 0.97 60993 8068 2 1009.553783 505.784 Anillin OS=Homo sapiens OX=9606 GN=ANLN PE=1 SV=2 5.66 1879.7 - 348728 - - - 0.2546 - 1.739 0.423 - 386.3 1 2 0 0.0003 9 0 0 0 1.18E+07 1.22E+07 - - - 3.766 0.9998 221125_WJC_METTL3_EV_vs_WT_F05.08070.08070.3 0.000663 Nov-40 K.LLSESAQPLKK.V sp|Q9H3N1|TMX1_HUMAN 1 1212.7078 1.15 60994 8070 3 1212.706898 405.2432 Thioredoxin-related transmembrane protein 1 OS=Homo sapiens OX=9606 GN=TMX1 PE=1 SV=1 8.59 1879.9 - 1.83E+06 - - - -0.7339 - 1.912 0.395 - 119.9 1 2 0 -0.0009 11 0 0 0 9.99E+07 8.71E+07 - - - 4.7849 0.9997 221125_WJC_METTL3_EV_vs_WT_F05.08072.08072.2 0.00886 18-Sep R.GPLPLSSQHR[166.11].G "sp|P43243|MATR3_HUMAN,tr|A8MXP9|A8MXP9_HUMAN,tr|D6R991|D6R991_HUMAN,tr|A0A0R4J2E8|A0A0R4J2E8_HUMAN,tr|D6R8Z5|D6R8Z5_HUMAN,tr|D6REM6|D6REM6_HUMAN" 6 1100.5966 1.34 60995 8072 2 1100.594862 551.3056 Matrin-3 OS=Homo sapiens OX=9606 GN=MATR3 PE=1 SV=2 9.76 1880.1 - 1.98E+07 - - - -1.59 - 1.733 0.488 - 301.2 1 2 0 -0.0018 10 0 0 0 1.69E+09 1.26E+09 - - - 4.1796 0.9998 221125_WJC_METTL3_EV_vs_WT_F05.08073.08073.2 0.00331 18-Oct R.NLEQENQNLR.M sp|Q8WVV4|POF1B_HUMAN 1 1256.6109 999 60996 8073 2 1256.611833 629.3127 Protein POF1B OS=Homo sapiens OX=9606 GN=POF1B PE=1 SV=3 4.53 1880.2 - 2.20E+06 - - - 0.7202 - 1.896 0.452 - 385.6 1 2 0 0.0009 10 0 0 0 9.87E+06 0.00E+00 - - - 4.1649 0.9935 221125_WJC_METTL3_EV_vs_WT_F05.08075.08075.2 0.112 20-Aug K.LLSESAQPLKK.V sp|Q9H3N1|TMX1_HUMAN 1 1212.7078 1.52 60998 8075 2 1212.710619 607.3612 Thioredoxin-related transmembrane protein 1 OS=Homo sapiens OX=9606 GN=TMX1 PE=1 SV=1 8.59 1880.4 - 290173 - - - 2.3344 - 1.347 0.251 - 169.3 1 2 0 0.0028 11 0 0 0 1.49E+07 9.78E+06 - - - 1.6998 0.9989 221125_WJC_METTL3_EV_vs_WT_F05.08076.08076.2 0.0325 26-Sep K.ALAQEDQGAGEVER[166.11].T sp|O15020|SPTN2_HUMAN 1 1481.6986 1.77 60999 8076 2 1481.695482 741.8566 "Spectrin beta chain, non-erythrocytic 2 OS=Homo sapiens OX=9606 GN=SPTBN2 PE=1 SV=3" 4 1880.5 - 207112 - - - -2.0841 - 1.884 0.332 - 129.7 1 2 0 -0.0031 14 0 0 0 8.87E+06 5.01E+06 - - - 3.0817 0.9995 221125_WJC_METTL3_EV_vs_WT_F05.08079.08079.2 0.000901 20-Oct K.VTNIGNQQIDK.V "sp|Q6P3W7|SCYL2_HUMAN,tr|F8VSC5|F8VSC5_HUMAN,tr|A0A0U1RQQ9|A0A0U1RQQ9_HUMAN" 3 1228.6412 1.71 61000 8079 2 1228.640409 615.3279 SCY1-like protein 2 OS=Homo sapiens OX=9606 GN=SCYL2 PE=1 SV=1 5.81 1880.9 - 2.61E+06 - - - -0.6153 - 2.121 0.259 - 192.6 1 2 0 -0.0008 11 0 0 0 1.57E+08 9.20E+07 - - - 2.9878 0.9996 221125_WJC_METTL3_EV_vs_WT_F05.08080.08080.3 0.00318 15/36 R.LQAVTDDHIR.M "sp|P30043|BLVRB_HUMAN,tr|A0A2R8YEP4|A0A2R8YEP4_HUMAN" 2 1166.6044 0.83 61001 8080 3 1166.600495 389.8754 Flavin reductase (NADPH) OS=Homo sapiens OX=9606 GN=BLVRB PE=1 SV=3 5.21 1881 - 1.42E+06 - - - -3.3353 - 2.928 0.336 - 293 1 2 0 -0.0039 10 0 0 0 1.26E+08 1.51E+08 - - - 5.4225 0.9993 221125_WJC_METTL3_EV_vs_WT_F05.08081.08081.3 0.0172 13/44 R.LAAQSQHVGFAR.S "sp|Q5VZL5|ZMYM4_HUMAN,tr|H7C1I7|H7C1I7_HUMAN" 2 1283.6735 0.66 61002 8081 3 1283.673111 428.8984 Zinc finger MYM-type protein 4 OS=Homo sapiens OX=9606 GN=ZMYM4 PE=1 SV=1 9.76 1881.2 - 899254 - - - -0.2781 - 2.044 0.27 - 214.1 1 2 0 -0.0004 12 0 0 0 1.84E+07 2.80E+07 - - - 3.5318 0.9999 221125_WJC_METTL3_EV_vs_WT_F05.08082.08082.3 0.00113 13/44 R.AAVMVYDDANK[136.11]K[136.11].W "sp|Q8N8S7|ENAH_HUMAN,tr|A0A075B6E5|A0A075B6E5_HUMAN,tr|A0A0U1RRM6|A0A0U1RRM6_HUMAN" 3 1339.6777 1.18 61003 8082 3 1339.675534 447.5665 Protein enabled homolog OS=Homo sapiens OX=9606 GN=ENAH PE=1 SV=2 6 1881.3 - 671555 - - - -1.6071 - 2.445 0.415 - 248.7 1 2 0 -0.0022 12 0 0 0 2.44E+07 2.08E+07 - - - 5.6444 1 221125_WJC_METTL3_EV_vs_WT_F05.08085.08085.2 1.12E-05 14/24 K.GPGEVAGTVTGQK[136.11].R "sp|Q86U44|MTA70_HUMAN,tr|F5H6D8|F5H6D8_HUMAN,tr|H0YFV6|H0YFV6_HUMAN,tr|B4DTN4|B4DTN4_HUMAN" 4 1207.6288 0.03 61004 8085 2 1207.625032 604.8217 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 6 1881.7 - 2.80E+06 - - - -3.1334 - 2.817 0.583 - 787.8 1 2 0 -0.0038 13 0 0 0 3.79E+09 1.37E+11 - - - 6.0039 0.8149 221125_WJC_METTL3_EV_vs_WT_F05.08087.08087.2 0.223 12-Aug F.QQSSLSR[166.11].D "sp|P43243|MATR3_HUMAN,tr|A0A1B0GX04|A0A1B0GX04_HUMAN,tr|D6RBS2|D6RBS2_HUMAN,tr|A8MXP9|A8MXP9_HUMAN,tr|D6R991|D6R991_HUMAN,tr|D6REK4|D6REK4_HUMAN,tr|D6R9F3|D6R9F3_HUMAN,tr|A0A0R4J2E8|A0A0R4J2E8_HUMAN,tr|D6RB45|D6RB45_HUMAN,tr|D6RCM3|D6RCM3_HUMAN,tr|D6R8Z5|D6R8Z5_HUMAN,tr|D6REM6|D6REM6_HUMAN" 12 814.4172 1.98 61006 8087 2 814.415493 408.2159 Matrin-3 OS=Homo sapiens OX=9606 GN=MATR3 PE=1 SV=2 9.75 1881.8 - 790676 - - - -2.1574 - 1.637 0.188 - 479.1 1 1 0 -0.0018 7 0 0 0 1.05E+08 5.28E+07 - - - 1.9907 0.9955 221125_WJC_METTL3_EV_vs_WT_F05.08093.08093.2 0.11 14-Aug R.VQDYIQSK.L sp|O60825|F262_HUMAN 1 979.4975 2.2 61010 8093 2 979.495143 490.756 "6-phosphofructo-2-kinase\fructose-2,6-bisphosphatase 2 OS=Homo sapiens OX=9606 GN=PFKFB2 PE=1 SV=2" 5.81 1882.5 - 2.28E+06 - - - -2.3665 - 1.417 0.255 - 176.6 1 2 0 -0.0023 8 0 0 0 4.51E+07 2.05E+07 - - - 1.9749 0.9935 221125_WJC_METTL3_EV_vs_WT_F05.08094.08094.2 0.000689 16-Nov K.IQINQEEER[166.11].L "sp|P42696|RBM34_HUMAN,tr|Q5TCT4|Q5TCT4_HUMAN,tr|A2A2V2|A2A2V2_HUMAN" 3 1167.5759 14 61011 8094 2 1167.569613 584.7952 RNA-binding protein 34 OS=Homo sapiens OX=9606 GN=RBM34 PE=1 SV=2 4.25 1882.7 - 1.01E+06 - - - -5.4155 - 1.901 0.391 - 400.7 1 2 0 -0.0063 9 0 0 0 3.74E+08 2.67E+07 - - - 3.7854 0.9994 221125_WJC_METTL3_EV_vs_WT_F05.08095.08095.2 0.000846 14/24 K.TLGTPTQPGSTPR.L sp|Q8NFH5|NUP35_HUMAN 1 1311.6783 1.82 61012 8095 2 1311.674692 656.8464 Nucleoporin NUP35 OS=Homo sapiens OX=9606 GN=NUP35 PE=1 SV=1 9.41 1882.8 - 732873 - - - -2.7347 - 2.232 0.436 - 618.4 1 2 0 -0.0036 13 0 0 0 2.11E+08 1.16E+08 - - - 4.3208 0.9991 221125_WJC_METTL3_EV_vs_WT_F05.08098.08098.3 8.73E-05 Sep-44 R.HAAAALAAMNGR.K "sp|P31483|TIA1_HUMAN,tr|F8W8I6|F8W8I6_HUMAN,tr|C9JTN7|C9JTN7_HUMAN,tr|H7BY49|H7BY49_HUMAN,tr|E5RG67|E5RG67_HUMAN,tr|E5RGV5|E5RGV5_HUMAN" 6 1152.5822 2.74 61013 8098 3 1152.57856 385.2013 Nucleolysin TIA-1 isoform p40 OS=Homo sapiens OX=9606 GN=TIA1 PE=1 SV=3 9.76 1883.2 - 1.60E+06 - - - -3.1668 - 2.022 0.365 - 65.2 1 2 0 -0.0037 12 0 0 0 3.85E+07 1.41E+07 - - - 4.56 0.9982 221125_WJC_METTL3_EV_vs_WT_F05.08102.08102.3 0.00151 Dec-44 K.EAHEPLAVADAK[136.11].L sp|Q9Y2X3|NOP58_HUMAN 1 1257.6445 1.88 61015 8102 3 1257.63973 420.2221 Nucleolar protein 58 OS=Homo sapiens OX=9606 GN=NOP58 PE=1 SV=1 4.65 1883.6 - 1.10E+06 - - - -3.7658 - 2.098 0.332 - 270.8 1 2 0 -0.0047 12 0 0 0 3.47E+07 1.85E+07 - - - 4.2941 0.8932 221125_WJC_METTL3_EV_vs_WT_F05.08106.08106.2 0.0959 16-Jun N.LTFMNESER[166.11].N "sp|Q8IZP7|H6ST3_HUMAN,tr|A0A087X0G1|A0A087X0G1_HUMAN" 2 1135.5207 0.06 61017 8106 2 1135.519091 568.7676 Heparan-sulfate 6-O-sulfotransferase 3 OS=Homo sapiens OX=9606 GN=HS6ST3 PE=2 SV=3 4.53 1884.1 - 2.05E+06 - - - -1.4425 - 1.205 0.345 - 103.6 1 1 0 -0.0016 9 0 0 0 3.43E+06 5.33E+07 - - - 2.1282 0.9998 221125_WJC_METTL3_EV_vs_WT_F05.08109.08109.2 0.000371 22-Dec R.QLC[160.03]GGSQAAIER[166.11].M sp|Q96S59|RANB9_HUMAN 1 1298.6277 1.13 61019 8109 2 1298.625002 650.3211 Ran-binding protein 9 OS=Homo sapiens OX=9606 GN=RANBP9 PE=1 SV=1 5.99 1884.4 - 619777 - - - -2.0422 - 2.612 0.528 - 619.9 1 2 0 -0.0027 12 0 0 0 1.69E+07 1.50E+07 - - - 5.4662 0.81 221125_WJC_METTL3_EV_vs_WT_F05.08111.08111.2 0.00485 14-Jul S.DNIQGITK[136.11].C "sp|Q99525|H4G_HUMAN,sp|P62805|H4_HUMAN" 2 895.4854 1.13 61021 8111 2 895.481748 448.75 Histone H4-like protein type G OS=Homo sapiens OX=9606 GN=H4C7 PE=1 SV=1 5.84 1884.6 - 1.14E+06 - - - -4.1296 - 1.681 0.366 - 238 1 1 0 -0.0037 8 0 0 0 2.19E+08 1.94E+08 - - - 3.3096 0.9968 221125_WJC_METTL3_EV_vs_WT_F05.08114.08114.2 0.00487 18-Oct R.LQAVTDDHIR[166.11].M "sp|P30043|BLVRB_HUMAN,tr|A0A2R8YEP4|A0A2R8YEP4_HUMAN" 2 1176.6127 0.54 61022 8114 2 1176.608114 589.3136 Flavin reductase (NADPH) OS=Homo sapiens OX=9606 GN=BLVRB PE=1 SV=3 5.21 1885 - 703163 - - - -3.8602 - 1.803 0.354 - 412.3 1 2 0 -0.0045 10 0 0 0 8.14E+06 1.52E+07 - - - 3.2996 0.9997 221125_WJC_METTL3_EV_vs_WT_F05.08115.08115.2 6.22E-06 13/22 R.QLC[160.03]GGSQAAIER.M sp|Q96S59|RANB9_HUMAN 1 1288.6194 1.13 61023 8115 2 1288.615748 645.317 Ran-binding protein 9 OS=Homo sapiens OX=9606 GN=RANBP9 PE=1 SV=1 5.99 1885.1 - 786622 - - - -2.8216 - 2.64 0.535 - 757.7 1 2 0 -0.0036 12 0 0 0 1.69E+07 1.50E+07 - - - 5.5457 0.7678 221125_WJC_METTL3_EV_vs_WT_F05.08116.08116.2 0.426 12-Jul F.QQSSLSR.D "sp|P43243|MATR3_HUMAN,tr|A0A1B0GX04|A0A1B0GX04_HUMAN,tr|D6RBS2|D6RBS2_HUMAN,tr|A8MXP9|A8MXP9_HUMAN,tr|D6R991|D6R991_HUMAN,tr|D6REK4|D6REK4_HUMAN,tr|D6R9F3|D6R9F3_HUMAN,tr|A0A0R4J2E8|A0A0R4J2E8_HUMAN,tr|D6RB45|D6RB45_HUMAN,tr|D6RCM3|D6RCM3_HUMAN,tr|D6R8Z5|D6R8Z5_HUMAN,tr|D6REM6|D6REM6_HUMAN" 12 804.409 1.27 61024 8116 2 804.407284 403.2118 Matrin-3 OS=Homo sapiens OX=9606 GN=MATR3 PE=1 SV=2 9.75 1885.2 - 3.77E+06 - - - -2.1084 - 1.538 0.18 - 359 1 1 0 -0.0017 7 0 0 0 6.71E+07 5.27E+07 - - - 1.734 0.9997 221125_WJC_METTL3_EV_vs_WT_F05.08117.08117.2 7.24E-06 22-Nov R.TMQNTSDLDTAR.C "sp|P14923|PLAK_HUMAN,tr|C9JKY1|C9JKY1_HUMAN,tr|C9JK18|C9JK18_HUMAN,tr|C9JTX4|C9JTX4_HUMAN,tr|C9J826|C9J826_HUMAN" 5 1351.6038 1371.77 61025 8117 2 1351.600664 676.8092 Junction plakoglobin OS=Homo sapiens OX=9606 GN=JUP PE=1 SV=3 4.21 1885.2 - 3.70E+06 - - - -2.315 - 1.922 0.573 - 128.2 1 2 0 -0.0031 12 0 0 0 8.26E+07 6.02E+04 - - - 4.9913 0.9212 221125_WJC_METTL3_EV_vs_WT_F05.08121.08121.2 0.00341 14-Jul S.DNIQGITK.C "sp|Q99525|H4G_HUMAN,sp|P62805|H4_HUMAN" 2 887.4712 1.13 61026 8121 2 887.468812 444.7429 Histone H4-like protein type G OS=Homo sapiens OX=9606 GN=H4C7 PE=1 SV=1 5.84 1885.8 - 2.97E+06 - - - -2.7426 - 1.534 0.402 - 309 1 1 0 -0.0024 8 0 0 0 2.19E+08 1.94E+08 - - - 3.2999 0.8762 221125_WJC_METTL3_EV_vs_WT_F05.08122.08122.2 0.0331 14-Aug R.TPENFPC[160.03]K.N sp|P00747|PLMN_HUMAN 1 991.4433 308.96 61027 8122 2 991.43407 496.7289 Plasminogen OS=Homo sapiens OX=9606 GN=PLG PE=1 SV=2 5.66 1885.9 - 1.27E+06 - - - -9.3268 - 1.301 0.36 - 298.8 1 2 0 -0.0092 8 0 0 0 2.55E+07 8.27E+04 - - - 2.4907 0.9997 221125_WJC_METTL3_EV_vs_WT_F05.08123.08123.3 0.0331 13/40 K.VNTLIR[166.11]PDGEK[136.11].K "sp|P62750|RL23A_HUMAN,tr|K7EMA7|K7EMA7_HUMAN,tr|H7BY10|H7BY10_HUMAN,tr|K7ERT8|K7ERT8_HUMAN,tr|A8MUS3|A8MUS3_HUMAN,tr|K7EJV9|K7EJV9_HUMAN" 6 1258.7 0.67 61028 8123 3 1258.696432 420.574 60S ribosomal protein L23a OS=Homo sapiens OX=9606 GN=RPL23A PE=1 SV=1 6.04 1886 - 2.39E+06 - - - -2.8514 - 2.667 0.363 - 314.4 1 2 0 -0.0036 11 0 0 0 1.38E+08 2.08E+08 - - - 5.3728 0.9993 221125_WJC_METTL3_EV_vs_WT_F05.08128.08128.2 0.000192 13/24 K.TLGTPTQPGSTPR[166.11].L sp|Q8NFH5|NUP35_HUMAN 1 1321.6865 1.82 61031 8128 2 1321.682958 661.8506 Nucleoporin NUP35 OS=Homo sapiens OX=9606 GN=NUP35 PE=1 SV=1 9.41 1886.6 - 1.71E+06 - - - -2.717 - 1.911 0.469 - 258.4 1 2 0 -0.0036 13 0 0 0 2.11E+08 1.16E+08 - - - 4.1661 0.9962 221125_WJC_METTL3_EV_vs_WT_F05.08129.08129.2 0.00758 14-Aug R.SC[160.03]QEVFDK.L sp|O43505|B4GA1_HUMAN 1 1011.4331 1.62 61032 8129 2 1011.429671 506.7238 "Beta-1,4-glucuronyltransferase 1 OS=Homo sapiens OX=9606 GN=B4GAT1 PE=1 SV=1" 4.37 1886.7 - 1.06E+06 - - - -3.4357 - 1.36 0.384 - 250.7 1 2 0 -0.0035 8 0 0 0 3.07E+07 1.89E+07 - - - 2.8035 0.8951 221125_WJC_METTL3_EV_vs_WT_F05.08131.08131.3 0.254 Dec-44 K.LGK[136.11]EPVLAAENK[136.11].D "sp|Q9H040|SPRTN_HUMAN,tr|B1AKT1|B1AKT1_HUMAN" 2 1283.742 1.86 61034 8131 3 1283.737285 428.9213 DNA-dependent metalloprotease SPRTN OS=Homo sapiens OX=9606 GN=SPRTN PE=1 SV=2 6.14 1887 - 604024 - - - -3.6744 - 1.584 0.228 - 123 1 2 1 -0.0047 12 0 0 0 1.28E+07 6.90E+06 - - - 2.3556 0.9608 221125_WJC_METTL3_EV_vs_WT_F05.08134.08134.2 0.443 16-Oct K.NIKEELATR.L "sp|P82094|TMF1_HUMAN,tr|F8WF45|F8WF45_HUMAN,tr|A0A2R8Y7M0|A0A2R8Y7M0_HUMAN" 3 1072.5877 999 61035 8134 2 1072.585294 537.3011 TATA element modulatory factor OS=Homo sapiens OX=9606 GN=TMF1 PE=1 SV=2 6.14 1887.4 - 3.55E+06 - - - -2.218 - 1.553 0.236 - 362.3 1 2 1 -0.0024 9 0 0 0 6.95E+07 0.00E+00 - - - 2.0568 0.9999 221125_WJC_METTL3_EV_vs_WT_F05.08135.08135.3 0.00302 14/48 R.VLSGTIHAGQPVK.V sp|Q15029|U5S1_HUMAN 1 1305.7405 2.04 61036 8135 3 1305.739891 436.2541 116 kDa U5 small nuclear ribonucleoprotein component OS=Homo sapiens OX=9606 GN=EFTUD2 PE=1 SV=1 8.73 1887.5 - 1.18E+06 - - - -0.4549 - 2.758 0.391 - 280.5 1 2 0 -0.0006 13 0 0 0 3.26E+08 1.59E+08 - - - 5.6497 1 221125_WJC_METTL3_EV_vs_WT_F05.08137.08137.3 0.000134 13/48 R.VLSGTIHAGQPVK[136.11].V sp|Q15029|U5S1_HUMAN 1 1313.7547 2.05 61038 8137 3 1313.75648 438.9255 116 kDa U5 small nuclear ribonucleoprotein component OS=Homo sapiens OX=9606 GN=EFTUD2 PE=1 SV=1 8.73 1887.7 - 681855 - - - 1.3663 - 2.568 0.466 - 215.6 1 2 0 0.0018 13 0 0 0 3.26E+08 1.59E+08 - - - 6.292 0.9998 221125_WJC_METTL3_EV_vs_WT_F05.08138.08138.2 1.34E-05 13/16 K.HVLSDLSTK.L "sp|Q9NUQ7|UFSP2_HUMAN,tr|D6RA67|D6RA67_HUMAN,tr|D6RB53|D6RB53_HUMAN,tr|D6RGX2|D6RGX2_HUMAN,tr|D6R9J7|D6R9J7_HUMAN" 5 998.5397 0.91 61039 8138 2 998.537556 500.2771 Ufm1-specific protease 2 OS=Homo sapiens OX=9606 GN=UFSP2 PE=1 SV=3 6.74 1887.9 - 662310 - - - -2.1071 - 2.347 0.508 - 565.3 1 2 0 -0.0021 9 0 0 0 3.11E+07 3.41E+07 - - - 5.2606 0.9756 221125_WJC_METTL3_EV_vs_WT_F05.08141.08141.2 0.0547 14-Jul R.DGPMK[136.11]FEK[136.11].D "sp|Q8ND56|LS14A_HUMAN,tr|A0A140TA76|A0A140TA76_HUMAN,tr|K7EMZ9|K7EMZ9_HUMAN" 3 966.4816 0.93 61040 8141 2 966.482646 484.2481 Protein LSM14 homolog A OS=Homo sapiens OX=9606 GN=LSM14A PE=1 SV=3 6.07 1888.3 - 2.18E+06 - - - 1.1309 - 1.32 0.285 - 145.3 1 2 1 0.0011 8 0 0 0 1.74E+08 1.86E+08 - - - 1.983 0.9984 221125_WJC_METTL3_EV_vs_WT_F05.08143.08143.2 0.0251 16-Jul K.ASNPEPSFK.A "sp|Q6W2J9|BCOR_HUMAN,tr|H7BZ37|H7BZ37_HUMAN,tr|A1A564|A1A564_HUMAN,tr|H7C2V9|H7C2V9_HUMAN,tr|H7BYY2|H7BYY2_HUMAN,tr|H7C231|H7C231_HUMAN" 6 975.4662 1.89 61042 8143 2 975.466872 488.7404 BCL-6 corepressor OS=Homo sapiens OX=9606 GN=BCOR PE=1 SV=1 6.05 1888.5 - 1.39E+06 - - - 0.7289 - 1.47 0.267 - 143.3 1 2 0 0.0007 9 0 0 0 1.94E+08 1.03E+08 - - - 2.1274 0.9992 221125_WJC_METTL3_EV_vs_WT_F05.08148.08148.3 0.0056 Nov-40 K.VNTLIRPDGEK.K "sp|P62750|RL23A_HUMAN,tr|K7EMA7|K7EMA7_HUMAN,tr|H7BY10|H7BY10_HUMAN,tr|K7ERT8|K7ERT8_HUMAN,tr|A8MUS3|A8MUS3_HUMAN,tr|K7EJV9|K7EJV9_HUMAN" 6 1240.6776 0.64 61045 8148 3 1240.678318 414.5665 60S ribosomal protein L23a OS=Homo sapiens OX=9606 GN=RPL23A PE=1 SV=1 6.04 1889.2 - 3.53E+06 - - - 0.6182 - 2.147 0.251 - 196.3 1 2 0 0.0008 11 0 0 0 1.34E+08 2.09E+08 - - - 3.5088 0.8492 221125_WJC_METTL3_EV_vs_WT_F05.08150.08150.2 1.62 12-Aug L.PLSSQHR[166.11].G "sp|P43243|MATR3_HUMAN,tr|A8MXP9|A8MXP9_HUMAN,tr|D6R991|D6R991_HUMAN,tr|A0A0R4J2E8|A0A0R4J2E8_HUMAN,tr|D6R8Z5|D6R8Z5_HUMAN,tr|D6REM6|D6REM6_HUMAN" 6 833.4383 1.28 61046 8150 2 833.43651 417.7264 Matrin-3 OS=Homo sapiens OX=9606 GN=MATR3 PE=1 SV=2 10.18 1889.4 - 9.40E+06 - - - -2.1717 - 1.618 0.222 - 203.1 1 1 0 -0.0018 7 0 0 0 9.72E+08 7.57E+08 - - - 2.2048 0.9582 221125_WJC_METTL3_EV_vs_WT_F05.08151.08151.2 0.414 16-Aug K.ASNPEPSFK[136.11].A "sp|Q6W2J9|BCOR_HUMAN,tr|H7BZ37|H7BZ37_HUMAN,tr|A1A564|A1A564_HUMAN,tr|H7C2V9|H7C2V9_HUMAN,tr|H7BYY2|H7BYY2_HUMAN,tr|H7C231|H7C231_HUMAN" 6 983.4804 2.01 61047 8151 2 983.476773 492.7475 BCL-6 corepressor OS=Homo sapiens OX=9606 GN=BCOR PE=1 SV=1 6.05 1889.5 - 613807 - - - -3.6483 - 1.339 0.147 - 250.6 1 2 0 -0.0036 9 0 0 0 1.93E+08 9.59E+07 - - - 0.9702 0.9984 221125_WJC_METTL3_EV_vs_WT_F05.08152.08152.2 0.00125 16-Jul R.FQVTTTANK.V "sp|Q9H4A3|WNK1_HUMAN,tr|F5GWT4|F5GWT4_HUMAN,tr|A0A6Q8PFM0|A0A6Q8PFM0_HUMAN" 3 1008.524 1.68 61048 8152 2 1008.522181 505.2693 Serine\threonine-protein kinase WNK1 OS=Homo sapiens OX=9606 GN=WNK1 PE=1 SV=2 8.75 1889.6 - 1.71E+06 - - - -1.8135 - 1.484 0.32 - 137.6 1 2 0 -0.0018 9 0 0 0 1.73E+08 1.03E+08 - - - 2.546 1 221125_WJC_METTL3_EV_vs_WT_F05.08154.08154.2 1.39E-06 14/24 R.VLSGTIHAGQPVK.V sp|Q15029|U5S1_HUMAN 1 1305.7405 2.32 61050 8154 2 1305.73783 653.8775 116 kDa U5 small nuclear ribonucleoprotein component OS=Homo sapiens OX=9606 GN=EFTUD2 PE=1 SV=1 8.73 1889.8 - 388159 - - - -2.0333 - 2.627 0.585 - 530.9 1 2 0 -0.0027 13 0 0 0 3.22E+07 1.39E+07 - - - 5.8398 0.9998 221125_WJC_METTL3_EV_vs_WT_F05.08156.08156.2 1.34E-05 18-Oct K.IQSQFTDAQK.H sp|P15924|DESP_HUMAN 1 1164.5775 18.23 61051 8156 2 1164.575533 583.296 Desmoplakin OS=Homo sapiens OX=9606 GN=DSP PE=1 SV=3 5.84 1890 - 1.32E+07 - - - -1.6907 - 2.058 0.554 - 257.3 1 2 0 -0.002 10 0 0 0 2.29E+08 1.26E+07 - - - 5.1468 1 221125_WJC_METTL3_EV_vs_WT_F05.08158.08158.2 1.32E-05 13/22 K.AAFTEC[160.03]C[160.03]QAADK.A "sp|P02768|ALBU_HUMAN,tr|B7WNR0|B7WNR0_HUMAN,tr|H0YA55|H0YA55_HUMAN,tr|A0A0C4DGB6|A0A0C4DGB6_HUMAN,tr|D6RHD5|D6RHD5_HUMAN" 5 1370.5595 999 61052 8158 2 1370.558864 686.287 Albumin OS=Homo sapiens OX=9606 GN=ALB PE=1 SV=2 4.37 1890.3 - 1.03E+06 - - - -0.4538 - 2.694 0.664 - 317.3 1 2 0 -0.0006 12 0 0 0 3.64E+07 0.00E+00 - - - 6.5527 0.9976 221125_WJC_METTL3_EV_vs_WT_F05.08160.08160.2 0.000213 14-Oct R.DGPMKFEK.D "sp|Q8ND56|LS14A_HUMAN,tr|A0A140TA76|A0A140TA76_HUMAN,tr|K7EMZ9|K7EMZ9_HUMAN" 3 950.4532 0.93 61054 8160 2 950.451927 476.2339 Protein LSM14 homolog A OS=Homo sapiens OX=9606 GN=LSM14A PE=1 SV=3 6.07 1890.4 - 2.76E+06 - - - -1.2899 - 1.891 0.473 - 429.3 1 2 1 -0.0012 8 0 0 0 1.74E+08 1.86E+08 - - - 4.4557 1 221125_WJC_METTL3_EV_vs_WT_F05.08164.08164.2 1.47E-07 13/24 K.GPGEVAGTVTGQK.R "sp|Q86U44|MTA70_HUMAN,tr|F5H6D8|F5H6D8_HUMAN,tr|H0YFV6|H0YFV6_HUMAN,tr|B4DTN4|B4DTN4_HUMAN" 4 1199.6146 0.03 61058 8164 2 1199.612348 600.8146 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 6 1891 - 464980 - - - -1.8906 - 2.623 0.571 - 681.2 1 2 0 -0.0023 13 0 0 0 3.79E+09 1.37E+11 - - - 5.7326 0.9986 221125_WJC_METTL3_EV_vs_WT_F05.08167.08167.2 0.0117 18-Jun R.GLEQGIQDNK[136.11].L sp|Q16706|MA2A1_HUMAN 1 1108.5604 1.15 61059 8167 2 1108.558752 555.2875 Alpha-mannosidase 2 OS=Homo sapiens OX=9606 GN=MAN2A1 PE=1 SV=2 4.37 1891.4 - 1.53E+06 - - - -1.4884 - 1.456 0.318 - 90.3 1 2 0 -0.0016 10 0 0 0 3.50E+07 3.05E+07 - - - 2.4379 0.9999 221125_WJC_METTL3_EV_vs_WT_F05.08168.08168.3 0.000141 15/36 R.AASADYLR[166.11]PR[166.11].L "sp|Q9NRA8|4ET_HUMAN,tr|B1AKL4|B1AKL4_HUMAN,tr|B0QYZ7|B0QYZ7_HUMAN" 3 1138.5998 0.001 61060 8168 3 1138.59756 380.5405 Eukaryotic translation initiation factor 4E transporter OS=Homo sapiens OX=9606 GN=EIF4ENIF1 PE=1 SV=2 8.79 1891.5 - 1.35E+06 - - - -1.9638 - 2.328 0.484 - 490.9 1 2 0 -0.0022 10 0 0 0 0.00E+00 5.05E+07 - - - 6.4033 0.9776 221125_WJC_METTL3_EV_vs_WT_F05.08171.08171.2 1.11 14-Sep K.LRDVLQQR.L "sp|Q12931|TRAP1_HUMAN,tr|I3L0K7|I3L0K7_HUMAN,tr|I3L239|I3L239_HUMAN" 3 1026.5934 3.52 61063 8171 2 1026.592391 514.304 "Heat shock protein 75 kDa, mitochondrial OS=Homo sapiens OX=9606 GN=TRAP1 PE=1 SV=3" 9.6 1891.9 - 503758 - - - -1.0092 - 1.641 0.188 - 181.7 1 2 1 -0.001 8 0 0 0 8.40E+06 2.39E+06 - - - 1.9231 0.9982 221125_WJC_METTL3_EV_vs_WT_F05.08173.08173.2 0.0687 14-Jun K.SNSSFMSR[166.11].E sp|Q9BSJ8|ESYT1_HUMAN 1 924.3999 2.23 61065 8173 2 924.400368 463.2072 Extended synaptotagmin-1 OS=Homo sapiens OX=9606 GN=ESYT1 PE=1 SV=1 9.47 1892.1 - 405359 - - - 0.5214 - 1.469 0.238 - 147.6 1 2 0 0.0005 8 0 0 0 1.68E+07 7.54E+06 - - - 1.9586 0.9992 221125_WJC_METTL3_EV_vs_WT_F05.08181.08181.3 0.00594 13/48 K.GPGEVAGTVTGQK[136.11].R "sp|Q86U44|MTA70_HUMAN,tr|F5H6D8|F5H6D8_HUMAN,tr|H0YFV6|H0YFV6_HUMAN,tr|B4DTN4|B4DTN4_HUMAN" 4 1207.6288 0.02 61071 8181 3 1207.62688 403.5502 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 6 1893.1 - 1.39E+06 - - - -1.6031 - 2.142 0.282 - 241.3 1 2 0 -0.0019 13 0 0 0 1.81E+08 8.08E+09 - - - 3.7488 0.9997 221125_WJC_METTL3_EV_vs_WT_F05.08182.08182.2 9.74E-05 16-Aug K.AQYEDIAQK.S sp|P04264|K2C1_HUMAN 1 1064.5138 10922.36 61072 8182 2 1064.512485 533.2642 "Keratin, type II cytoskeletal 1 OS=Homo sapiens OX=9606 GN=KRT1 PE=1 SV=6" 4.37 1893.2 - 3.50E+06 - - - -1.2719 - 1.625 0.457 - 212.9 1 2 0 -0.0014 9 0 0 0 4.25E+10 3.89E+06 - - - 3.8206 0.9992 221125_WJC_METTL3_EV_vs_WT_F05.08184.08184.2 0.102 22-Oct K.LQEAPSAASQMK.R "sp|Q5JSZ5|PRC2B_HUMAN,tr|A0A804HJR4|A0A804HJR4_HUMAN" 2 1259.618 1.51 61074 8184 2 1259.61876 630.8163 Protein PRRC2B OS=Homo sapiens OX=9606 GN=PRRC2B PE=1 SV=2 6 1893.4 - 824995 - - - 0.6137 - 1.902 0.265 - 336.9 1 2 0 0.0008 12 0 0 0 1.03E+07 6.80E+06 - - - 2.6896 0.9975 221125_WJC_METTL3_EV_vs_WT_F05.08187.08187.2 0.147 18-Jul R.AASADYLRPR.L "sp|Q9NRA8|4ET_HUMAN,tr|B1AKL4|B1AKL4_HUMAN,tr|B0QYZ7|B0QYZ7_HUMAN" 3 1118.5833 1.84 61077 8187 2 1118.585268 560.2989 Eukaryotic translation initiation factor 4E transporter OS=Homo sapiens OX=9606 GN=EIF4ENIF1 PE=1 SV=2 8.79 1893.7 - 330844 - - - 1.7987 - 1.443 0.29 - 90.4 1 2 0 0.002 10 0 0 0 1.35E+07 7.32E+06 - - - 2.2059 0.9999 221125_WJC_METTL3_EV_vs_WT_F05.08192.08192.2 0.00363 13/20 K.VNTLIR[166.11]PDGEK[136.11].K "sp|P62750|RL23A_HUMAN,tr|K7EMA7|K7EMA7_HUMAN,tr|H7BY10|H7BY10_HUMAN,tr|K7ERT8|K7ERT8_HUMAN,tr|A8MUS3|A8MUS3_HUMAN,tr|K7EJV9|K7EJV9_HUMAN" 6 1258.7 0.39 61080 8192 2 1258.699689 630.3573 60S ribosomal protein L23a OS=Homo sapiens OX=9606 GN=RPL23A PE=1 SV=1 6.04 1894.4 - 694422 - - - -0.2638 - 2.555 0.404 - 730.2 1 2 0 -0.0003 11 0 0 0 8.30E+06 2.15E+07 - - - 4.5625 0.9999 221125_WJC_METTL3_EV_vs_WT_F05.08194.08194.2 0.000314 18-Oct K.YEELQQTAGR.H "sp|P13647|K2C5_HUMAN,tr|H0YI76|H0YI76_HUMAN,tr|H0YIN9|H0YIN9_HUMAN" 3 1193.5677 999 61082 8194 2 1193.567776 597.7911 "Keratin, type II cytoskeletal 5 OS=Homo sapiens OX=9606 GN=KRT5 PE=1 SV=3" 4.53 1894.6 - 469293 - - - 0.0922 - 2.129 0.492 - 348 1 2 0 0.0001 10 0 0 0 1.04E+07 0.00E+00 - - - 4.7841 0.9992 221125_WJC_METTL3_EV_vs_WT_F05.08195.08195.2 0.0796 22-Aug K.LQEAPSAASQMK[136.11].R "sp|Q5JSZ5|PRC2B_HUMAN,tr|A0A804HJR4|A0A804HJR4_HUMAN" 2 1267.6322 1.51 61083 8195 2 1267.632359 634.8234 Protein PRRC2B OS=Homo sapiens OX=9606 GN=PRRC2B PE=1 SV=2 6 1894.7 - 324526 - - - 0.1357 - 1.675 0.293 - 224.3 1 2 0 0.0002 12 0 0 0 1.03E+07 6.80E+06 - - - 2.5622 0.9997 221125_WJC_METTL3_EV_vs_WT_F05.08199.08199.2 0.000372 16-Nov K.C[160.03]C[160.03]TESLVNR.R "sp|P02768|ALBU_HUMAN,tr|A0A087WWT3|A0A087WWT3_HUMAN,tr|B7WNR0|B7WNR0_HUMAN,tr|H0YA55|H0YA55_HUMAN,tr|A0A0C4DGB6|A0A0C4DGB6_HUMAN,tr|D6RHD5|D6RHD5_HUMAN,tr|C9JKR2|C9JKR2_HUMAN" 7 1137.4907 999 61085 8199 2 1137.487882 569.7526 Albumin OS=Homo sapiens OX=9606 GN=ALB PE=1 SV=2 5.99 1895.2 - 1.22E+06 - - - -2.458 - 2.31 0.543 - 661.5 1 2 0 -0.0028 9 0 0 0 1.55E+08 0.00E+00 - - - 5.4729 0.9998 221125_WJC_METTL3_EV_vs_WT_F05.08201.08201.3 0.00103 Oct-40 R.K[136.11]LVNTINPGAR[166.11].F sp|Q92900|RENT1_HUMAN 1 1199.7105 1.12 61087 8201 3 1199.709006 400.9108 Regulator of nonsense transcripts 1 OS=Homo sapiens OX=9606 GN=UPF1 PE=1 SV=2 11 1895.4 - 837448 - - - -1.267 - 2.079 0.348 - 112.1 1 2 0 -0.0015 11 0 0 0 1.92E+07 1.71E+07 - - - 4.4986 0.9998 221125_WJC_METTL3_EV_vs_WT_F05.08204.08204.2 0.000115 18-Nov R.GIHNSIGDYR.W sp|P15924|DESP_HUMAN 1 1130.5469 34.39 61088 8204 2 1130.546492 566.2807 Desmoplakin OS=Homo sapiens OX=9606 GN=DSP PE=1 SV=3 6.74 1895.9 - 751187 - - - -0.3352 - 1.741 0.475 - 351.8 1 2 0 -0.0004 10 0 0 0 4.55E+07 1.32E+06 - - - 4.0969 0.9995 221125_WJC_METTL3_EV_vs_WT_F05.08205.08205.2 0.166 20-Sep K.IQELQASQEAR[166.11].A sp|Q9Y6D9|MD1L1_HUMAN 1 1281.6552 1.7 61089 8205 2 1281.654684 641.8349 Mitotic spindle assembly checkpoint protein MAD1 OS=Homo sapiens OX=9606 GN=MAD1L1 PE=1 SV=2 4.53 1896 - 265776 - - - -0.4408 - 1.963 0.291 - 406.3 1 2 0 -0.0006 11 0 0 0 1.66E+08 9.74E+07 - - - 3.0148 0.9981 221125_WJC_METTL3_EV_vs_WT_F05.08210.08210.2 0.00778 14-Dec K.KGDIVDIK.G "sp|P46778|RL21_HUMAN,tr|G3V1B3|G3V1B3_HUMAN,tr|M0R181|M0R181_HUMAN" 3 886.5124 1.02 61092 8210 2 886.511304 444.2635 60S ribosomal protein L21 OS=Homo sapiens OX=9606 GN=RPL21 PE=1 SV=2 5.96 1896.7 - 3.11E+06 - - - -1.2171 - 2.163 0.091 - 628.1 1 2 0 -0.0011 8 0 0 0 1.25E+08 1.22E+08 - - - 2.0396 0.9991 221125_WJC_METTL3_EV_vs_WT_F05.08216.08216.2 0.000136 18-Nov R.QASPTEVVER[166.11].L "sp|Q8TB72|PUM2_HUMAN,tr|A0A0C4DG68|A0A0C4DG68_HUMAN,tr|C9JW01|C9JW01_HUMAN" 3 1124.5701 1.58 61096 8216 2 1124.573246 563.2923 Pumilio homolog 2 OS=Homo sapiens OX=9606 GN=PUM2 PE=1 SV=2 4.53 1897.4 - 610385 - - - 2.778 - 2.073 0.388 - 608.5 1 2 0 0.0031 10 0 0 0 2.12E+08 1.34E+08 - - - 3.9406 0.9997 221125_WJC_METTL3_EV_vs_WT_F05.08220.08220.3 2.99E-05 Dec-40 R.VLK[136.11]EEGNELVK[136.11].K sp|Q15785|TOM34_HUMAN 1 1272.726 5.45 61098 8220 3 1272.722862 425.2493 Mitochondrial import receptor subunit TOM34 OS=Homo sapiens OX=9606 GN=TOMM34 PE=1 SV=2 4.79 1898 - 1.13E+06 - - - -2.4789 - 2.4 0.52 - 149.7 1 2 1 -0.0032 11 0 0 0 1.65E+08 3.02E+07 - - - 6.8237 0.8757 221125_WJC_METTL3_EV_vs_WT_F05.08221.08221.3 0.237 Aug-40 R.KLVNTINPGAR.F sp|Q92900|RENT1_HUMAN 1 1181.6881 1.12 61099 8221 3 1181.686197 394.9033 Regulator of nonsense transcripts 1 OS=Homo sapiens OX=9606 GN=UPF1 PE=1 SV=2 11 1898.1 - 1.16E+06 - - - -1.5732 - 1.184 0.131 - 55.4 1 2 0 -0.0019 11 0 0 0 1.92E+07 1.71E+07 - - - 0.4798 0.8762 221125_WJC_METTL3_EV_vs_WT_F05.08222.08222.2 0.199 14-Jul A.QYEDIAQK.S sp|P04264|K2C1_HUMAN 1 993.4767 198.27 61100 8222 2 993.475108 497.7456 "Keratin, type II cytoskeletal 1 OS=Homo sapiens OX=9606 GN=KRT1 PE=1 SV=6" 4.37 1898.2 - 1.41E+06 - - - -1.6276 - 1.458 0.258 - 212.8 1 1 0 -0.0016 8 0 0 0 1.28E+08 6.45E+05 - - - 2.0833 0.9996 221125_WJC_METTL3_EV_vs_WT_F05.08236.08236.2 0.000326 18-Sep R.GPLPLSSQHR.G "sp|P43243|MATR3_HUMAN,tr|A8MXP9|A8MXP9_HUMAN,tr|D6R991|D6R991_HUMAN,tr|A0A0R4J2E8|A0A0R4J2E8_HUMAN,tr|D6R8Z5|D6R8Z5_HUMAN,tr|D6REM6|D6REM6_HUMAN" 6 1090.5883 1.39 61111 8236 2 1090.585663 546.3014 Matrin-3 OS=Homo sapiens OX=9606 GN=MATR3 PE=1 SV=2 9.76 1899.9 - 7.77E+06 - - - -2.4565 - 1.923 0.535 - 270.5 1 2 0 -0.0027 10 0 0 0 3.47E+08 2.50E+08 - - - 4.8169 0.9968 221125_WJC_METTL3_EV_vs_WT_F05.08241.08241.2 0.114 16-Oct R.YR[166.11]PGTVALR[166.11].E "sp|Q5TEC6|H3PS2_HUMAN,sp|Q16695|H31T_HUMAN,sp|P84243|H33_HUMAN,sp|Q6NXT2|H3C_HUMAN,sp|Q71DI3|H32_HUMAN,sp|P68431|H31_HUMAN,tr|B4DEB1|B4DEB1_HUMAN,tr|K7EK07|K7EK07_HUMAN,tr|K7ES00|K7ES00_HUMAN,tr|K7EP01|K7EP01_HUMAN,tr|K7EMV3|K7EMV3_HUMAN,tr|A0A590UJJ6|A0A590UJJ6_HUMAN" 12 1051.6042 0.99 61115 8241 2 1051.606182 526.8094 Histone HIST2H3PS2 OS=Homo sapiens OX=9606 GN=H3-2 PE=1 SV=1 10.84 1900.4 - 1.40E+06 - - - 1.9294 - 1.709 0.2 - 232.1 1 2 0 0.002 9 0 0 0 6.76E+07 6.81E+07 - - - 2.068 0.9296 221125_WJC_METTL3_EV_vs_WT_F05.08243.08243.2 0.612 16-Sep R.YRPGTVALR.E "sp|Q5TEC6|H3PS2_HUMAN,sp|Q16695|H31T_HUMAN,sp|P84243|H33_HUMAN,sp|Q6NXT2|H3C_HUMAN,sp|Q71DI3|H32_HUMAN,sp|P68431|H31_HUMAN,tr|B4DEB1|B4DEB1_HUMAN,tr|K7EK07|K7EK07_HUMAN,tr|K7ES00|K7ES00_HUMAN,tr|K7EP01|K7EP01_HUMAN,tr|K7EMV3|K7EMV3_HUMAN,tr|A0A590UJJ6|A0A590UJJ6_HUMAN" 12 1031.5876 0.99 61117 8243 2 1031.58551 516.8011 Histone HIST2H3PS2 OS=Homo sapiens OX=9606 GN=H3-2 PE=1 SV=1 10.84 1900.7 - 1.11E+06 - - - -2.0386 - 1.298 0.005 - 166.2 1 2 0 -0.0021 9 0 0 0 6.76E+07 6.81E+07 - - - -0.1682 0.9956 221125_WJC_METTL3_EV_vs_WT_F05.08249.08249.2 0.0248 18-Jun K.NIGVDNPAAK[136.11].V "sp|P78371|TCPB_HUMAN,tr|F8VQ14|F8VQ14_HUMAN,tr|F5GWF6|F5GWF6_HUMAN" 3 1005.5335 0.83 61121 8249 2 1005.531045 503.774 T-complex protein 1 subunit beta OS=Homo sapiens OX=9606 GN=CCT2 PE=1 SV=4 5.84 1901.3 - 2.18E+06 - - - -2.4007 - 1.305 0.301 - 82.2 1 2 0 -0.0024 10 0 0 0 5.06E+07 6.12E+07 - - - 2.0065 0.9989 221125_WJC_METTL3_EV_vs_WT_F05.08255.08255.2 0.000219 16-Oct R.DTNAPESFK[136.11].D "sp|Q15643|TRIPB_HUMAN,tr|H0YJ97|H0YJ97_HUMAN" 2 1015.4702 1.53 61125 8255 2 1015.4665 508.7424 Thyroid receptor-interacting protein 11 OS=Homo sapiens OX=9606 GN=TRIP11 PE=1 SV=3 4.37 1902 - 788558 - - - -3.6338 - 1.953 0.48 - 449 1 2 0 -0.0037 9 0 0 0 4.33E+07 2.83E+07 - - - 4.5216 0.9889 221125_WJC_METTL3_EV_vs_WT_F05.08258.08258.3 0.0229 Dec-32 K.YEK[136.11]DIAAYR[166.11].A "sp|P26583|HMGB2_HUMAN,sp|P09429|HMGB1_HUMAN" 2 1145.5836 0.001 61127 8258 3 1145.580234 382.8685 High mobility group protein B2 OS=Homo sapiens OX=9606 GN=HMGB2 PE=1 SV=2 6.07 1902.4 - 997013 - - - -2.933 - 1.938 0.274 - 211 1 2 1 -0.0034 9 0 0 0 0.00E+00 1.57E+08 - - - 3.588 0.9998 221125_WJC_METTL3_EV_vs_WT_F05.08259.08259.2 2.24E-05 22-Nov R.LC[160.03]TSATESEVAR.G sp|P31930|QCR1_HUMAN 1 1322.6136 1.47 61128 8259 2 1322.615901 662.3141 "Cytochrome b-c1 complex subunit 1, mitochondrial OS=Homo sapiens OX=9606 GN=UQCRC1 PE=1 SV=3" 4.53 1902.5 - 706675 - - - 1.7171 - 2.229 0.592 - 443.6 1 2 0 0.0023 12 0 0 0 1.36E+07 9.22E+06 - - - 5.5218 0.9964 221125_WJC_METTL3_EV_vs_WT_F05.08262.08262.2 1.59E-06 26-Dec R.LTPVSPESSSTEEK.S "sp|Q13501|SQSTM_HUMAN,tr|E7EMC7|E7EMC7_HUMAN" 2 1489.7148 2.45 61129 8262 2 1489.706203 745.8647 Sequestosome-1 OS=Homo sapiens OX=9606 GN=SQSTM1 PE=1 SV=1 4.25 1902.9 - 940313 - - - -5.7602 - 1.872 0.596 - 350.7 1 2 0 -0.0086 14 0 0 0 6.68E+07 2.73E+07 - - - 5.0138 0.9915 221125_WJC_METTL3_EV_vs_WT_F05.08266.08266.2 3 16-Oct K.SFQQSSLSR.D "sp|P43243|MATR3_HUMAN,tr|A0A1B0GX04|A0A1B0GX04_HUMAN,tr|D6RBS2|D6RBS2_HUMAN,tr|A8MXP9|A8MXP9_HUMAN,tr|D6R991|D6R991_HUMAN,tr|D6REK4|D6REK4_HUMAN,tr|D6R9F3|D6R9F3_HUMAN,tr|A0A0R4J2E8|A0A0R4J2E8_HUMAN,tr|D6RB45|D6RB45_HUMAN,tr|D6RCM3|D6RCM3_HUMAN,tr|D6R8Z5|D6R8Z5_HUMAN,tr|D6REM6|D6REM6_HUMAN" 12 1038.5094 1.24 61131 8266 2 1038.505746 520.262 Matrin-3 OS=Homo sapiens OX=9606 GN=MATR3 PE=1 SV=2 9.47 1903.3 - 1.74E+06 - - - -3.5407 - 1.569 0.245 - 395.1 1 2 0 -0.0037 9 0 0 0 1.11E+08 8.98E+07 - - - 2.1526 0.9994 221125_WJC_METTL3_EV_vs_WT_F05.08270.08270.2 0.00166 16-Aug R.FFSEQQQSK.Q "sp|Q9Y520|PRC2C_HUMAN,tr|E7EPN9|E7EPN9_HUMAN,tr|H7C5N8|H7C5N8_HUMAN,tr|A0A2R8YET2|A0A2R8YET2_HUMAN" 4 1127.5247 2.08 61133 8270 2 1127.523248 564.7696 Protein PRRC2C OS=Homo sapiens OX=9606 GN=PRRC2C PE=1 SV=4 6 1903.7 - 1.89E+06 - - - -1.3215 - 1.525 0.385 - 112.3 1 2 0 -0.0015 9 0 0 0 1.15E+08 5.54E+07 - - - 3.105 0.9982 221125_WJC_METTL3_EV_vs_WT_F05.08271.08271.2 3.58E-07 26-Nov R.LTPVSPESSSTEEK[136.11].S "sp|Q13501|SQSTM_HUMAN,tr|E7EMC7|E7EMC7_HUMAN" 2 1497.729 2.45 61134 8271 2 1497.721504 749.8718 Sequestosome-1 OS=Homo sapiens OX=9606 GN=SQSTM1 PE=1 SV=1 4.25 1903.9 - 832551 - - - -4.9942 - 1.946 0.622 - 272.6 1 2 0 -0.0075 14 0 0 0 6.68E+07 2.73E+07 - - - 5.3035 0.9987 221125_WJC_METTL3_EV_vs_WT_F05.08272.08272.3 0.0164 Nov-40 R.VNAVPRPIPEK.K sp|Q9HD45|TM9S3_HUMAN 1 1218.7085 1.9 61135 8272 3 1218.705663 407.2434 Transmembrane 9 superfamily member 3 OS=Homo sapiens OX=9606 GN=TM9SF3 PE=1 SV=2 8.72 1904 - 1.78E+06 - - - -2.2926 - 2.066 0.279 - 187.2 1 2 0 -0.0028 11 0 0 0 7.59E+07 3.99E+07 - - - 3.7111 0.9996 221125_WJC_METTL3_EV_vs_WT_F05.08274.08274.2 1.25E-06 22-Oct R.AQTSGIEEETVK.E "sp|P55197|AF10_HUMAN,tr|Q5JT35|Q5JT35_HUMAN,tr|H0Y5P4|H0Y5P4_HUMAN" 3 1290.6303 11.24 61137 8274 2 1290.626577 646.3224 Protein AF-10 OS=Homo sapiens OX=9606 GN=MLLT10 PE=1 SV=2 4.25 1904.2 - 716997 - - - -2.9048 - 2.277 0.532 - 336.3 1 2 0 -0.0037 12 0 0 0 1.96E+07 1.75E+06 - - - 5.1343 0.9843 221125_WJC_METTL3_EV_vs_WT_F05.08277.08277.2 0.00154 24-Dec L.LAALGGNSSPSAK.D sp|P05387|RLA2_HUMAN 1 1171.6197 1.55 61138 8277 2 1171.620015 586.8171 60S acidic ribosomal protein P2 OS=Homo sapiens OX=9606 GN=RPLP2 PE=1 SV=1 8.75 1904.6 - 1.08E+06 - - - 0.268 - 2.282 0.352 - 435.4 1 1 0 0.0003 13 0 0 0 1.69E+08 1.09E+08 - - - 3.7583 0.9733 221125_WJC_METTL3_EV_vs_WT_F05.08279.08279.2 0.0404 24-Nov L.LAALGGNSSPSAK[136.11].D sp|P05387|RLA2_HUMAN 1 1179.6339 1.44 61140 8279 2 1179.631794 590.8242 60S acidic ribosomal protein P2 OS=Homo sapiens OX=9606 GN=RPLP2 PE=1 SV=1 8.75 1904.9 - 763086 - - - -1.7861 - 2.234 0.368 - 360.8 1 1 0 -0.0021 13 0 0 0 1.57E+08 1.09E+08 - - - 3.8213 0.9997 221125_WJC_METTL3_EV_vs_WT_F05.08282.08282.2 0.00553 14-Oct R.TSFTSVSR.S "sp|P13647|K2C5_HUMAN,tr|F8VV57|F8VV57_HUMAN,tr|F8VU69|F8VU69_HUMAN" 3 883.4399 96.86 61141 8282 2 883.438517 442.7272 "Keratin, type II cytoskeletal 5 OS=Homo sapiens OX=9606 GN=KRT5 PE=1 SV=3" 9.41 1905.4 - 2.33E+06 - - - -1.6175 - 1.868 0.431 - 435.4 1 2 0 -0.0014 8 0 0 0 1.37E+08 1.41E+06 - - - 4.1085 0.9984 221125_WJC_METTL3_EV_vs_WT_F05.08284.08284.2 0.000206 16-Oct R.DTNAPESFK.D "sp|Q15643|TRIPB_HUMAN,tr|H0YJ97|H0YJ97_HUMAN" 2 1007.456 1.53 61143 8284 2 1007.453046 504.7353 Thyroid receptor-interacting protein 11 OS=Homo sapiens OX=9606 GN=TRIP11 PE=1 SV=3 4.37 1905.6 - 1.04E+06 - - - -2.9222 - 1.485 0.427 - 327.3 1 2 0 -0.0029 9 0 0 0 4.33E+07 2.83E+07 - - - 3.3379 0.9279 221125_WJC_METTL3_EV_vs_WT_F05.08285.08285.2 0.0642 14-Aug P.LPLSSQHR.G "sp|P43243|MATR3_HUMAN,tr|A8MXP9|A8MXP9_HUMAN,tr|D6R991|D6R991_HUMAN,tr|A0A0R4J2E8|A0A0R4J2E8_HUMAN,tr|D6R8Z5|D6R8Z5_HUMAN,tr|D6REM6|D6REM6_HUMAN" 6 936.5141 1.72 61144 8285 2 936.513538 469.2643 Matrin-3 OS=Homo sapiens OX=9606 GN=MATR3 PE=1 SV=2 9.76 1905.8 - 769900 - - - -0.615 - 1.461 0.272 - 267 1 1 0 -0.0006 8 0 0 0 7.13E+07 4.14E+07 - - - 2.1932 0.9985 221125_WJC_METTL3_EV_vs_WT_F05.08286.08286.2 0.000865 18-Oct K.VDSQYPPVQR.L sp|P49790|NU153_HUMAN 1 1187.5935 0.08 61145 8286 2 1187.58914 594.804 Nuclear pore complex protein Nup153 OS=Homo sapiens OX=9606 GN=NUP153 PE=1 SV=2 5.81 1905.9 - 688773 - - - -3.6603 - 1.937 0.426 - 292.4 1 2 0 -0.0043 10 0 0 0 1.43E+07 1.88E+08 - - - 4.0315 0.9994 221125_WJC_METTL3_EV_vs_WT_F05.08294.08294.2 0.000104 18-Oct R.QASPTEVVER.L "sp|Q8TB72|PUM2_HUMAN,tr|A0A0C4DG68|A0A0C4DG68_HUMAN,tr|C9JW01|C9JW01_HUMAN" 3 1114.5619 1.59 61149 8294 2 1114.558518 558.2882 Pumilio homolog 2 OS=Homo sapiens OX=9606 GN=PUM2 PE=1 SV=2 4.53 1906.9 - 5.48E+06 - - - -2.9913 - 2.237 0.44 - 498.2 1 2 0 -0.0033 10 0 0 0 2.12E+08 1.33E+08 - - - 4.5372 0.9966 221125_WJC_METTL3_EV_vs_WT_F05.08297.08297.3 0.0122 Nov-48 K.GPGEVAGTVTGQK.R "sp|Q86U44|MTA70_HUMAN,tr|F5H6D8|F5H6D8_HUMAN,tr|H0YFV6|H0YFV6_HUMAN,tr|B4DTN4|B4DTN4_HUMAN" 4 1199.6146 0.02 61152 8297 3 1199.610622 400.8788 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 6 1907.3 - 639986 - - - -3.3294 - 1.979 0.284 - 122.7 1 2 0 -0.004 13 0 0 0 1.74E+08 8.04E+09 - - - 3.5559 0.9985 221125_WJC_METTL3_EV_vs_WT_F05.08303.08303.3 9.14E-05 Dec-36 R.FEPYANPTK[136.11]R[166.11].Y "sp|P52272|HNRPM_HUMAN,tr|M0R019|M0R019_HUMAN,tr|M0R0Y6|M0R0Y6_HUMAN,tr|M0R0N3|M0R0N3_HUMAN,tr|A0A087X0X3|A0A087X0X3_HUMAN,tr|M0QYQ7|M0QYQ7_HUMAN,tr|M0R2T0|M0R2T0_HUMAN" 7 1239.6367 1.7 61156 8303 3 1239.632805 414.2195 Heterogeneous nuclear ribonucleoprotein M OS=Homo sapiens OX=9606 GN=HNRNPM PE=1 SV=3 8.59 1907.9 - 1.92E+06 - - - -3.1356 - 1.969 0.317 - 195.3 1 2 0 -0.0039 10 0 0 0 1.18E+09 6.95E+08 - - - 4.0518 0.9998 221125_WJC_METTL3_EV_vs_WT_F05.08304.08304.3 0.00253 Dec-40 K.GLSSHVEVVEK.E sp|Q96T58|MINT_HUMAN 1 1182.6245 0.12 61157 8304 3 1182.622572 395.2154 Msx2-interacting protein OS=Homo sapiens OX=9606 GN=SPEN PE=1 SV=1 5.4 1908.1 - 857158 - - - -1.5897 - 2.329 0.373 - 145.5 1 2 0 -0.0019 11 0 0 0 2.25E+07 1.82E+08 - - - 5.0998 0.8169 221125_WJC_METTL3_EV_vs_WT_F05.08307.08307.2 20.4 16-Aug K.SFQQSSLSR[166.11].D "sp|P43243|MATR3_HUMAN,tr|A0A1B0GX04|A0A1B0GX04_HUMAN,tr|D6RBS2|D6RBS2_HUMAN,tr|A8MXP9|A8MXP9_HUMAN,tr|D6R991|D6R991_HUMAN,tr|D6REK4|D6REK4_HUMAN,tr|D6R9F3|D6R9F3_HUMAN,tr|A0A0R4J2E8|A0A0R4J2E8_HUMAN,tr|D6RB45|D6RB45_HUMAN,tr|D6RCM3|D6RCM3_HUMAN,tr|D6R8Z5|D6R8Z5_HUMAN,tr|D6REM6|D6REM6_HUMAN" 12 1048.5177 0.82 61158 8307 2 1048.522087 525.2661 Matrin-3 OS=Homo sapiens OX=9606 GN=MATR3 PE=1 SV=2 9.47 1908.5 - 1.46E+06 - - - 4.1907 - 1.201 0.08 - 191.7 1 2 0 0.0044 9 0 0 0 5.42E+07 6.61E+07 - - - 0.1604 0.9309 221125_WJC_METTL3_EV_vs_WT_F05.08308.08308.2 0.00165 22-Jul K.SVAQQASLTEQR.L sp|P52306|GDS1_HUMAN 1 1316.6684 1.09 61159 8308 2 1316.656299 659.3415 Rap1 GTPase-GDP dissociation stimulator 1 OS=Homo sapiens OX=9606 GN=RAP1GDS1 PE=1 SV=3 5.72 1908.6 - 346850 - - - -9.2225 - 1.66 0.372 - 140.8 1 2 0 -0.0121 12 0 0 0 2.15E+06 1.98E+06 - - - 3.1183 0.9969 221125_WJC_METTL3_EV_vs_WT_F05.08312.08312.2 0.208 14-Aug R.QQQEQLLK.Q sp|P48634|PRC2A_HUMAN 1 1013.5506 1.09 61163 8312 2 1013.549566 507.7826 Protein PRRC2A OS=Homo sapiens OX=9606 GN=PRRC2A PE=1 SV=3 6 1909.1 - 481767 - - - -0.9797 - 1.377 0.215 - 279.1 1 2 0 -0.001 8 0 0 0 1.87E+08 1.73E+08 - - - 1.5935 0.9997 221125_WJC_METTL3_EV_vs_WT_F05.08315.08315.2 0.00098 16-Sep K.ESEFDDEPK.F "sp|Q9Y2W1|TR150_HUMAN,tr|A0A3B3ITZ9|A0A3B3ITZ9_HUMAN" 2 1094.4404 2.86 61164 8315 2 1094.437671 548.2275 Thyroid hormone receptor-associated protein 3 OS=Homo sapiens OX=9606 GN=THRAP3 PE=1 SV=2 3.83 1909.5 - 9.12E+06 - - - -2.4935 - 1.679 0.626 - 348.9 1 2 0 -0.0027 9 0 0 0 2.29E+10 8.01E+09 - - - 5.163 0.9935 221125_WJC_METTL3_EV_vs_WT_F05.08316.08316.2 0.214 14-Sep R.QQQEQLLK[136.11].Q sp|P48634|PRC2A_HUMAN 1 1021.5648 1.09 61165 8316 2 1021.562978 511.7897 Protein PRRC2A OS=Homo sapiens OX=9606 GN=PRRC2A PE=1 SV=3 6 1909.6 - 835609 - - - -1.7434 - 1.502 0.145 - 411.2 1 2 0 -0.0018 8 0 0 0 1.88E+08 1.73E+08 - - - 1.3383 0.9999 221125_WJC_METTL3_EV_vs_WT_F05.08317.08317.3 0.000124 15/40 R.LDGAHAPELTK[136.11].K sp|O76003|GLRX3_HUMAN 1 1158.6124 1.68 61166 8317 3 1158.610935 387.2114 Glutaredoxin-3 OS=Homo sapiens OX=9606 GN=GLRX3 PE=1 SV=2 5.32 1909.7 - 954896 - - - -1.2972 - 2.561 0.406 - 198.4 1 2 0 -0.0015 11 0 0 0 9.15E+07 5.44E+07 - - - 5.7376 0.9985 221125_WJC_METTL3_EV_vs_WT_F05.08318.08318.3 0.00122 Nov-48 K.VGTLVGEDKYGNK.Y "sp|Q9UI09|NDUAC_HUMAN,tr|H0YID5|H0YID5_HUMAN,tr|F8VRD8|F8VRD8_HUMAN,tr|H0YIT1|H0YIT1_HUMAN,tr|A0A804HJF8|A0A804HJF8_HUMAN,tr|A0A804HK60|A0A804HK60_HUMAN,tr|A0A804HHX9|A0A804HHX9_HUMAN" 7 1378.7092 2.76 61167 8318 3 1378.707156 460.577 NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 12 OS=Homo sapiens OX=9606 GN=NDUFA12 PE=1 SV=1 6.04 1909.9 - 514251 - - - -1.5152 - 1.927 0.366 - 166.9 1 2 1 -0.0021 13 0 0 0 8.89E+06 3.22E+06 - - - 4.3985 0.9993 221125_WJC_METTL3_EV_vs_WT_F05.08323.08323.2 0.00017 16-Sep K.ESEFDDEPK[136.11].F "sp|Q9Y2W1|TR150_HUMAN,tr|A0A3B3ITZ9|A0A3B3ITZ9_HUMAN" 2 1102.4546 2.85 61170 8323 2 1102.45246 552.2346 Thyroid hormone receptor-associated protein 3 OS=Homo sapiens OX=9606 GN=THRAP3 PE=1 SV=2 3.83 1910.5 - 6.66E+06 - - - -1.9411 - 1.722 0.388 - 340.5 1 2 0 -0.0021 9 0 0 0 2.18E+10 7.65E+09 - - - 3.4784 0.9999 221125_WJC_METTL3_EV_vs_WT_F05.08325.08325.3 0.000205 Nov-36 R.FEPYANPTKR.Y "sp|P52272|HNRPM_HUMAN,tr|M0R019|M0R019_HUMAN,tr|M0R0Y6|M0R0Y6_HUMAN,tr|M0R0N3|M0R0N3_HUMAN,tr|A0A087X0X3|A0A087X0X3_HUMAN,tr|M0QYQ7|M0QYQ7_HUMAN,tr|M0R2T0|M0R2T0_HUMAN" 7 1221.6142 1.7 61172 8325 3 1221.613854 408.212 Heterogeneous nuclear ribonucleoprotein M OS=Homo sapiens OX=9606 GN=HNRNPM PE=1 SV=3 8.59 1910.7 - 4.93E+06 - - - -0.3012 - 1.84 0.433 - 159.5 1 2 0 -0.0004 10 0 0 0 1.18E+09 6.95E+08 - - - 5.1482 0.9696 221125_WJC_METTL3_EV_vs_WT_F05.08331.08331.2 0.000411 16-Aug H.GSGGPSWTR[166.11].E "sp|O00746|NDKM_HUMAN,tr|A0A087WVT9|A0A087WVT9_HUMAN,tr|H0Y6J0|H0Y6J0_HUMAN,tr|F2Z2X0|F2Z2X0_HUMAN" 4 913.4281 1.9 61175 8331 2 913.426321 457.7214 "Nucleoside diphosphate kinase, mitochondrial OS=Homo sapiens OX=9606 GN=NME4 PE=1 SV=1" 9.75 1911.4 - 858548 - - - -2.0013 - 1.839 0.411 - 254.1 1 1 0 -0.0018 9 0 0 0 5.68E+09 2.99E+09 - - - 3.8386 0.9985 221125_WJC_METTL3_EV_vs_WT_F05.08332.08332.3 0.00697 Sep-36 R.IHEAAVQELR[166.11].Q "sp|Q7Z406|MYH14_HUMAN,tr|A0A0C4DFM8|A0A0C4DFM8_HUMAN" 2 1174.6334 3.87 61176 8332 3 1174.630117 392.5517 Myosin-14 OS=Homo sapiens OX=9606 GN=MYH14 PE=1 SV=2 5.4 1911.5 - 776630 - - - -2.7873 - 2.083 0.288 - 180.5 1 2 0 -0.0033 10 0 0 0 4.58E+07 1.18E+07 - - - 3.8931 0.9721 221125_WJC_METTL3_EV_vs_WT_F05.08333.08333.2 0.00177 16-Oct H.GSGGPSWTR.E "sp|O00746|NDKM_HUMAN,tr|A0A087WVT9|A0A087WVT9_HUMAN,tr|H0Y6J0|H0Y6J0_HUMAN,tr|F2Z2X0|F2Z2X0_HUMAN" 4 903.4199 1.9 61177 8333 2 903.417959 452.7172 "Nucleoside diphosphate kinase, mitochondrial OS=Homo sapiens OX=9606 GN=NME4 PE=1 SV=1" 9.75 1911.7 - 853052 - - - -2.1253 - 2.078 0.394 - 478.2 1 1 0 -0.0019 9 0 0 0 5.68E+09 2.99E+09 - - - 4.0665 0.9996 221125_WJC_METTL3_EV_vs_WT_F05.08334.08334.2 0.000889 18-Jun R.FEPYANPTK[136.11]R[166.11].Y "sp|P52272|HNRPM_HUMAN,tr|M0R019|M0R019_HUMAN,tr|M0R0Y6|M0R0Y6_HUMAN,tr|M0R0N3|M0R0N3_HUMAN,tr|A0A087X0X3|A0A087X0X3_HUMAN,tr|M0QYQ7|M0QYQ7_HUMAN,tr|M0R2T0|M0R2T0_HUMAN" 7 1239.6367 2.12 61178 8334 2 1239.63576 620.8256 Heterogeneous nuclear ribonucleoprotein M OS=Homo sapiens OX=9606 GN=HNRNPM PE=1 SV=3 8.59 1911.8 - 534428 - - - -0.7518 - 1.387 0.45 - 137.3 1 2 0 -0.0009 10 0 0 0 1.79E+08 8.44E+07 - - - 3.2776 1 221125_WJC_METTL3_EV_vs_WT_F05.08336.08336.2 1.23E-06 14/24 K.GPGEVAGTVTGQK[136.11].R "sp|Q86U44|MTA70_HUMAN,tr|F5H6D8|F5H6D8_HUMAN,tr|H0YFV6|H0YFV6_HUMAN,tr|B4DTN4|B4DTN4_HUMAN" 4 1207.6288 0.03 61179 8336 2 1207.628164 604.8217 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 6 1912 - 5.65E+08 - - - -0.5399 - 3.004 0.635 - 922.5 1 2 0 -0.0007 13 0 0 0 3.79E+09 1.37E+11 - - - 6.5539 0.9996 221125_WJC_METTL3_EV_vs_WT_F05.08339.08339.3 0.00482 Dec-40 R.LDGAHAPELTK.K sp|O76003|GLRX3_HUMAN 1 1150.5982 1.64 61181 8339 3 1150.595845 384.54 Glutaredoxin-3 OS=Homo sapiens OX=9606 GN=GLRX3 PE=1 SV=2 5.32 1912.3 - 2.15E+06 - - - -2.0798 - 2.021 0.358 - 112.5 1 2 0 -0.0024 11 0 0 0 9.35E+07 5.70E+07 - - - 4.5295 0.9392 221125_WJC_METTL3_EV_vs_WT_F05.08342.08342.2 1.27 18-Jun R.IHEAAVQELR.Q "sp|Q7Z406|MYH14_HUMAN,tr|A0A0C4DFM8|A0A0C4DFM8_HUMAN" 2 1164.6251 1.77 61184 8342 2 1164.626965 583.3198 Myosin-14 OS=Homo sapiens OX=9606 GN=MYH14 PE=1 SV=2 5.4 1912.7 - 364741 - - - 1.5833 - 1.272 0.03 - 121.1 2 2 0 0.0018 10 0 0 0 8.15E+06 4.62E+06 - - - -0.2009 0.9718 221125_WJC_METTL3_EV_vs_WT_F05.08345.08345.2 0.469 14-Jul R.R[166.11]LQTQVFK[136.11].L "sp|P46781|RS9_HUMAN,tr|C9JM19|C9JM19_HUMAN,tr|B5MCT8|B5MCT8_HUMAN" 3 1036.6148 0.99 61185 8345 2 1036.613213 519.3147 40S ribosomal protein S9 OS=Homo sapiens OX=9606 GN=RPS9 PE=1 SV=3 11 1913.1 - 3.34E+06 - - - -1.5637 - 1.47 0.005 - 260.6 1 2 0 -0.0016 8 0 0 0 1.79E+08 1.81E+08 - - - 0.2394 1 221125_WJC_METTL3_EV_vs_WT_F05.08346.08346.3 1.97E-06 16/52 M.AAAGAAATHLEVAR.G "sp|Q96S52|PIGS_HUMAN,tr|K7EN97|K7EN97_HUMAN" 2 1307.6946 3.26 61186 8346 3 1307.693168 436.9055 GPI transamidase component PIG-S OS=Homo sapiens OX=9606 GN=PIGS PE=1 SV=3 6.79 1913.2 - 727125 - - - -1.0935 - 3.273 0.562 - 405.1 1 2 0 -0.0014 14 0 0 0 1.27E+07 3.89E+06 - - - 7.9564 0.9968 221125_WJC_METTL3_EV_vs_WT_F05.08347.08347.2 0.0464 18-Aug R.FEPYANPTKR.Y "sp|P52272|HNRPM_HUMAN,tr|M0R019|M0R019_HUMAN,tr|M0R0Y6|M0R0Y6_HUMAN,tr|M0R0N3|M0R0N3_HUMAN,tr|A0A087X0X3|A0A087X0X3_HUMAN,tr|M0QYQ7|M0QYQ7_HUMAN,tr|M0R2T0|M0R2T0_HUMAN" 7 1221.6142 2.12 61187 8347 2 1221.613218 611.8144 Heterogeneous nuclear ribonucleoprotein M OS=Homo sapiens OX=9606 GN=HNRNPM PE=1 SV=3 8.59 1913.3 - 1.08E+06 - - - -0.8219 - 1.186 0.27 - 181.8 1 2 0 -0.001 10 0 0 0 1.79E+08 8.44E+07 - - - 1.5111 0.9289 221125_WJC_METTL3_EV_vs_WT_F05.08349.08349.2 1.33 12-Jun K.RPFLEPK.K "sp|P78347|GTF2I_HUMAN,tr|A0A494C1K3|A0A494C1K3_HUMAN" 2 885.5072 1.78 61189 8349 2 885.504377 443.7609 General transcription factor II-I OS=Homo sapiens OX=9606 GN=GTF2I PE=1 SV=2 8.75 1913.6 - 969745 - - - -3.2309 - 1.196 0.105 - 169.8 1 2 0 -0.0029 7 0 0 0 2.85E+07 1.61E+07 - - - 0.3827 1 221125_WJC_METTL3_EV_vs_WT_F05.08350.08350.2 6.60E-08 22-Nov K.EAMEDGEIDGNK.V "sp|P19338|NUCL_HUMAN,tr|A0A7I2V699|A0A7I2V699_HUMAN,tr|A0A7I2V3F3|A0A7I2V3F3_HUMAN,tr|A0A7I2V428|A0A7I2V428_HUMAN,tr|H7BY16|H7BY16_HUMAN,tr|C9JLB1|C9JLB1_HUMAN" 6 1306.5347 1.31 61190 8350 2 1306.530813 654.2746 Nucleolin OS=Homo sapiens OX=9606 GN=NCL PE=1 SV=3 3.83 1913.7 - 556467 - - - -2.9835 - 2.238 0.657 - 434.3 1 2 0 -0.0039 12 0 0 0 5.97E+07 4.54E+07 - - - 6.012 1 221125_WJC_METTL3_EV_vs_WT_F05.08353.08353.2 1.03E-08 22-Dec K.EAMEDGEIDGNK[136.11].V "sp|P19338|NUCL_HUMAN,tr|A0A7I2V699|A0A7I2V699_HUMAN,tr|A0A7I2V3F3|A0A7I2V3F3_HUMAN,tr|A0A7I2V428|A0A7I2V428_HUMAN,tr|H7BY16|H7BY16_HUMAN,tr|C9JLB1|C9JLB1_HUMAN" 6 1314.5489 1.31 61191 8353 2 1314.54543 658.2817 Nucleolin OS=Homo sapiens OX=9606 GN=NCL PE=1 SV=3 3.83 1914.1 - 659313 - - - -2.6481 - 2.357 0.722 - 538 1 2 0 -0.0035 12 0 0 0 5.97E+07 4.54E+07 - - - 6.6285 0.9991 221125_WJC_METTL3_EV_vs_WT_F05.08359.08359.2 0.0391 18-Aug K.EVQTVTSIQK[136.11].A "sp|O60524|NEMF_HUMAN,tr|G3V5V3|G3V5V3_HUMAN" 2 1139.6278 1.25 61194 8359 2 1139.626535 570.8212 Nuclear export mediator factor NEMF OS=Homo sapiens OX=9606 GN=NEMF PE=1 SV=4 6.1 1914.8 - 1.15E+06 - - - -1.0688 - 1.627 0.307 - 198.8 1 2 0 -0.0012 10 0 0 0 3.51E+07 2.80E+07 - - - 2.6668 0.992 221125_WJC_METTL3_EV_vs_WT_F05.08368.08368.2 0.32 14-Aug R.RLQTQVFK.L "sp|P46781|RS9_HUMAN,tr|C9JM19|C9JM19_HUMAN,tr|B5MCT8|B5MCT8_HUMAN" 3 1018.5924 0.99 61197 8368 2 1018.590067 510.3035 40S ribosomal protein S9 OS=Homo sapiens OX=9606 GN=RPS9 PE=1 SV=3 11 1916 - 7.48E+06 - - - -2.2551 - 1.768 0.094 - 307.6 1 2 0 -0.0023 8 0 0 0 1.79E+08 1.81E+08 - - - 1.4532 0.7828 221125_WJC_METTL3_EV_vs_WT_F05.08369.08369.3 0.291 Oct-36 K.TFQGK[136.11]PIMAR[166.11].L "sp|Q71RC2|LARP4_HUMAN,tr|Q96J85|Q96J85_HUMAN,tr|X6RLN4|X6RLN4_HUMAN" 3 1165.6397 0.87 61198 8369 3 1165.633482 389.5538 La-related protein 4 OS=Homo sapiens OX=9606 GN=LARP4 PE=1 SV=3 11 1916.1 - 1.21E+06 - - - -5.3078 - 1.577 0.157 - 150.9 1 2 0 -0.0062 10 0 0 0 4.77E+07 5.47E+07 - - - 1.619 0.9993 221125_WJC_METTL3_EV_vs_WT_F05.08374.08374.2 0.00176 16-Sep K.SFYSSHYAR.E "sp|Q8NEY8|PPHLN_HUMAN,tr|B7Z8L1|B7Z8L1_HUMAN,tr|F8VWU8|F8VWU8_HUMAN,tr|F8W6A0|F8W6A0_HUMAN,tr|F8W0Q9|F8W0Q9_HUMAN,tr|F8WF16|F8WF16_HUMAN,tr|F8VPY7|F8VPY7_HUMAN" 7 1116.4989 0.94 61201 8374 2 1116.496056 559.2567 Periphilin-1 OS=Homo sapiens OX=9606 GN=PPHLN1 PE=1 SV=2 8.33 1916.7 - 1.45E+06 - - - -2.5096 - 1.6 0.483 - 285.6 1 2 0 -0.0028 9 0 0 0 3.26E+07 3.48E+07 - - - 3.9673 0.9998 221125_WJC_METTL3_EV_vs_WT_F05.08376.08376.2 0.00453 22-Nov K.SYSSGGEDGYVR[166.11].L "sp|Q13347|EIF3I_HUMAN,tr|A0A7I2YQT9|A0A7I2YQT9_HUMAN,tr|A0A7I2YQU2|A0A7I2YQU2_HUMAN,tr|A0A7I2YQF8|A0A7I2YQF8_HUMAN,tr|A0A7I2V3U3|A0A7I2V3U3_HUMAN,tr|A0A7I2V5V8|A0A7I2V5V8_HUMAN,tr|A0A7I2V4C2|A0A7I2V4C2_HUMAN,tr|A0A7I2YQC8|A0A7I2YQC8_HUMAN" 8 1285.545 1.15 61203 8376 2 1285.543002 643.7798 Eukaryotic translation initiation factor 3 subunit I OS=Homo sapiens OX=9606 GN=EIF3I PE=1 SV=1 4.37 1917 - 1.30E+06 - - - -1.5775 - 2.009 0.504 - 262.3 1 2 0 -0.002 12 0 0 0 2.14E+08 1.86E+08 - - - 4.5985 0.9991 221125_WJC_METTL3_EV_vs_WT_F05.08377.08377.2 0.00309 14-Nov K.RGGFNTFR.D "sp|P17844|DDX5_HUMAN,tr|J3KTA4|J3KTA4_HUMAN,tr|A0A0G2JLI4|A0A0G2JLI4_HUMAN" 3 953.4831 1.63 61204 8377 2 953.480476 477.7489 Probable ATP-dependent RNA helicase DDX5 OS=Homo sapiens OX=9606 GN=DDX5 PE=1 SV=1 12 1917.1 - 821722 - - - -2.8024 - 1.945 0.381 - 307.5 1 2 0 -0.0027 8 0 0 0 9.67E+07 5.92E+07 - - - 3.8606 0.9995 221125_WJC_METTL3_EV_vs_WT_F05.08386.08386.2 0.000586 20-Nov K.IIEDQQESLNK[136.11].W sp|P05455|LA_HUMAN 1 1323.6762 0.94 61209 8386 2 1323.672396 662.8454 Lupus La protein OS=Homo sapiens OX=9606 GN=SSB PE=1 SV=2 4.14 1918.3 - 823947 - - - -2.8436 - 2.037 0.513 - 297.1 1 2 0 -0.0038 11 0 0 0 8.46E+07 8.98E+07 - - - 4.7536 1 221125_WJC_METTL3_EV_vs_WT_F05.08387.08387.2 7.25E-05 22-Dec K.SYSSGGEDGYVR.L "sp|Q13347|EIF3I_HUMAN,tr|A0A7I2YQT9|A0A7I2YQT9_HUMAN,tr|A0A7I2YQU2|A0A7I2YQU2_HUMAN,tr|A0A7I2YQF8|A0A7I2YQF8_HUMAN,tr|A0A7I2V3U3|A0A7I2V3U3_HUMAN,tr|A0A7I2V5V8|A0A7I2V5V8_HUMAN,tr|A0A7I2V4C2|A0A7I2V4C2_HUMAN,tr|A0A7I2YQC8|A0A7I2YQC8_HUMAN" 8 1275.5368 1.15 61210 8387 2 1275.533013 638.7757 Eukaryotic translation initiation factor 3 subunit I OS=Homo sapiens OX=9606 GN=EIF3I PE=1 SV=1 4.37 1918.4 - 2.10E+06 - - - -2.9376 - 2.192 0.632 - 368 1 2 0 -0.0037 12 0 0 0 2.14E+08 1.86E+08 - - - 5.7728 0.9987 221125_WJC_METTL3_EV_vs_WT_F05.08389.08389.2 0.0104 14-Jul R.GTLDPVEK[136.11].A "sp|P11142|HSP7C_HUMAN,tr|E9PNE6|E9PNE6_HUMAN,tr|A8K7Q2|A8K7Q2_HUMAN,tr|E9PKE3|E9PKE3_HUMAN,tr|E9PN89|E9PN89_HUMAN" 5 865.4636 0.16 61212 8389 2 865.46208 433.7391 Heat shock cognate 71 kDa protein OS=Homo sapiens OX=9606 GN=HSPA8 PE=1 SV=1 4.37 1918.6 - 1.69E+06 - - - -1.8117 - 1.669 0.286 - 222.5 1 2 0 -0.0016 8 0 0 0 1.90E+07 1.22E+08 - - - 2.6977 0.8875 221125_WJC_METTL3_EV_vs_WT_F05.08394.08394.2 0.00302 24-Aug G.GSYGSGGGGGGGR.G sp|P04264|K2C1_HUMAN 1 1024.4322 21.61 61215 8394 2 1024.429915 513.2234 "Keratin, type II cytoskeletal 1 OS=Homo sapiens OX=9606 GN=KRT1 PE=1 SV=6" 8.75 1919.2 - 2.03E+06 - - - -2.2647 - 1.507 0.334 - 152.8 1 1 0 -0.0023 13 0 0 0 1.96E+08 9.08E+06 - - - 2.5598 0.9974 221125_WJC_METTL3_EV_vs_WT_F05.08395.08395.2 0.00017 16-Sep K.SFYSSHYAR[166.11].E "sp|Q8NEY8|PPHLN_HUMAN,tr|B7Z8L1|B7Z8L1_HUMAN,tr|F8VWU8|F8VWU8_HUMAN,tr|F8W6A0|F8W6A0_HUMAN,tr|F8W0Q9|F8W0Q9_HUMAN,tr|F8WF16|F8WF16_HUMAN,tr|F8VPY7|F8VPY7_HUMAN" 7 1126.5071 0.84 61216 8395 2 1126.50305 564.2608 Periphilin-1 OS=Homo sapiens OX=9606 GN=PPHLN1 PE=1 SV=2 8.33 1919.4 - 1.32E+06 - - - -3.62 - 1.551 0.408 - 267.7 1 2 0 -0.0041 9 0 0 0 3.26E+07 3.91E+07 - - - 3.323 0.9987 221125_WJC_METTL3_EV_vs_WT_F05.08400.08400.2 0.00175 14-Oct K.R[166.11]GGFNTFR[166.11].D "sp|P17844|DDX5_HUMAN,tr|J3KTA4|J3KTA4_HUMAN,tr|A0A0G2JLI4|A0A0G2JLI4_HUMAN" 3 973.4997 1.64 61219 8400 2 973.497198 487.7571 Probable ATP-dependent RNA helicase DDX5 OS=Homo sapiens OX=9606 GN=DDX5 PE=1 SV=1 12 1920 - 1.94E+06 - - - -2.5578 - 1.788 0.334 - 240.8 1 2 0 -0.0025 8 0 0 0 9.69E+07 5.92E+07 - - - 3.2597 0.9881 221125_WJC_METTL3_EV_vs_WT_F05.08401.08401.2 0.00691 16-Sep R.EDLPVNTSK.T "sp|Q86UE4|LYRIC_HUMAN,tr|E5RJU9|E5RJU9_HUMAN" 2 1001.5029 1.07 61220 8401 2 1001.500129 501.7587 Protein LYRIC OS=Homo sapiens OX=9606 GN=MTDH PE=1 SV=2 4.37 1920.1 - 1.29E+06 - - - -2.8068 - 1.43 0.187 - 245.6 1 2 0 -0.0028 9 0 0 0 5.11E+07 4.79E+07 - - - 1.4561 0.9998 221125_WJC_METTL3_EV_vs_WT_F05.08404.08404.2 0.00144 20-Nov K.IIEDQQESLNK.W sp|P05455|LA_HUMAN 1 1315.662 0.94 61221 8404 2 1315.660867 658.8383 Lupus La protein OS=Homo sapiens OX=9606 GN=SSB PE=1 SV=2 4.14 1920.5 - 3.47E+06 - - - -0.8308 - 2.004 0.47 - 281 1 2 0 -0.0011 11 0 0 0 8.43E+07 8.98E+07 - - - 4.3926 0.9859 221125_WJC_METTL3_EV_vs_WT_F05.08405.08405.2 0.268 12-Jul K.K[136.11]HLEDEL.- sp|O95881|TXD12_HUMAN 1 890.4589 1.66 61222 8405 2 890.457324 446.2367 Thioredoxin domain-containing protein 12 OS=Homo sapiens OX=9606 GN=TXNDC12 PE=1 SV=1 4.65 1920.6 - 1.20E+06 - - - -1.7665 - 1.202 0.159 - 146.1 1 2 0 -0.0016 7 0 0 0 4.13E+07 2.49E+07 - - - 0.7979 1 221125_WJC_METTL3_EV_vs_WT_F05.08409.08409.2 8.48E-06 13/24 K.GPGEVAGTVTGQK.R "sp|Q86U44|MTA70_HUMAN,tr|F5H6D8|F5H6D8_HUMAN,tr|H0YFV6|H0YFV6_HUMAN,tr|B4DTN4|B4DTN4_HUMAN" 4 1199.6146 0.03 61224 8409 2 1199.614096 600.8146 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 6 1921.2 - 2.82E+07 - - - -0.4335 - 2.852 0.598 - 661.8 1 2 0 -0.0005 13 0 0 0 3.79E+09 1.37E+11 - - - 6.1474 0.9998 221125_WJC_METTL3_EV_vs_WT_F05.08412.08412.2 4.68E-08 13/20 R.YLSEVASGDNK.Q sp|P31946|1433B_HUMAN 1 1181.5564 2.59 61227 8412 2 1181.553846 591.7855 14-3-3 protein beta\alpha OS=Homo sapiens OX=9606 GN=YWHAB PE=1 SV=3 4.37 1921.5 - 970532 - - - -2.1886 - 2.213 0.555 - 446.9 1 2 0 -0.0026 11 0 0 0 2.71E+07 1.05E+07 - - - 5.2883 0.928 221125_WJC_METTL3_EV_vs_WT_F05.08423.08423.2 0.00196 14-Aug E.PYANPTK[136.11]R[166.11].Y "sp|P52272|HNRPM_HUMAN,tr|M0R019|M0R019_HUMAN,tr|M0R0Y6|M0R0Y6_HUMAN,tr|M0R0N3|M0R0N3_HUMAN,tr|A0A087X0X3|A0A087X0X3_HUMAN,tr|M0QYQ7|M0QYQ7_HUMAN,tr|M0R2T0|M0R2T0_HUMAN" 7 963.5257 1.78 61233 8423 2 963.522821 482.7701 Heterogeneous nuclear ribonucleoprotein M OS=Homo sapiens OX=9606 GN=HNRNPM PE=1 SV=3 10.01 1922.7 - 1.63E+06 - - - -2.9724 - 1.57 0.433 - 218.3 1 1 0 -0.0029 8 0 0 0 1.38E+08 7.75E+07 - - - 3.5987 0.9988 221125_WJC_METTL3_EV_vs_WT_F05.08427.08427.3 0.0039 13/36 R.YYPTEDVPR[166.11]K[136.11].L "sp|Q02878|RL6_HUMAN,tr|F8VZ45|F8VZ45_HUMAN,tr|F8VR69|F8VR69_HUMAN,tr|U3KQR5|U3KQR5_HUMAN" 4 1284.6469 1.21 61235 8427 3 1284.644667 429.2229 60S ribosomal protein L6 OS=Homo sapiens OX=9606 GN=RPL6 PE=1 SV=3 6.07 1923.2 - 1.18E+06 - - - -1.7553 - 1.914 0.276 - 166.4 1 2 0 -0.0023 10 0 0 0 3.60E+07 2.98E+07 - - - 3.5124 0.9998 221125_WJC_METTL3_EV_vs_WT_F05.08428.08428.2 0.0136 13/20 R.QLEEAEEEATR.A sp|P35580|MYH10_HUMAN 1 1303.5892 1.01 61236 8428 2 1303.591468 652.8019 Myosin-10 OS=Homo sapiens OX=9606 GN=MYH10 PE=1 SV=3 3.98 1923.3 - 1.37E+06 - - - 1.7483 - 2.335 0.48 - 955.2 1 2 0 0.0023 11 0 0 0 1.69E+08 1.67E+08 - - - 4.8796 0.9995 221125_WJC_METTL3_EV_vs_WT_F05.08430.08430.3 0.000131 Nov-48 K.GPGEVAGTVTGQK[136.11].R "sp|Q86U44|MTA70_HUMAN,tr|F5H6D8|F5H6D8_HUMAN,tr|H0YFV6|H0YFV6_HUMAN,tr|B4DTN4|B4DTN4_HUMAN" 4 1207.6288 0.02 61237 8430 3 1207.625822 403.5502 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 6 1923.6 - 1.05E+08 - - - -2.4792 - 1.975 0.381 - 169.2 1 2 0 -0.003 13 0 0 0 1.75E+08 8.06E+09 - - - 4.6322 0.9665 221125_WJC_METTL3_EV_vs_WT_F05.08432.08432.3 0.138 Oct-48 K.EGVVHGVATVAEK.T "sp|P37840|SYUA_HUMAN,tr|A0A669KB41|A0A669KB41_HUMAN,tr|D6RA31|D6RA31_HUMAN,tr|A0A669KBH5|A0A669KBH5_HUMAN,tr|E7EPV7|E7EPV7_HUMAN" 5 1294.6881 1.66 61239 8432 3 1294.684857 432.57 Alpha-synuclein OS=Homo sapiens OX=9606 GN=SNCA PE=1 SV=1 5.4 1923.7 - 6.13E+06 - - - -2.5164 - 1.733 0.145 - 171.7 1 2 0 -0.0033 13 0 0 0 2.23E+09 1.34E+09 - - - 1.6465 0.9942 221125_WJC_METTL3_EV_vs_WT_F05.08433.08433.3 0.041 Sep-48 K.EGVVHGVATVAEK[136.11].T "sp|P37840|SYUA_HUMAN,tr|A0A669KB41|A0A669KB41_HUMAN,tr|D6RA31|D6RA31_HUMAN,tr|A0A669KBH5|A0A669KBH5_HUMAN,tr|E7EPV7|E7EPV7_HUMAN" 5 1302.7023 1.66 61240 8433 3 1302.699544 435.2414 Alpha-synuclein OS=Homo sapiens OX=9606 GN=SNCA PE=1 SV=1 5.4 1923.7 - 4.16E+06 - - - -2.1271 - 1.848 0.213 - 126.5 1 2 0 -0.0028 13 0 0 0 2.23E+09 1.34E+09 - - - 2.579 0.9999 221125_WJC_METTL3_EV_vs_WT_F05.08438.08438.2 0.000139 13/20 R.QLEEAEEEATR[166.11].A sp|P35580|MYH10_HUMAN 1 1313.5975 1.01 61243 8438 2 1313.59713 657.806 Myosin-10 OS=Homo sapiens OX=9606 GN=MYH10 PE=1 SV=3 3.98 1924.3 - 3.07E+06 - - - -0.2505 - 2.502 0.475 - 772.9 1 2 0 -0.0003 11 0 0 0 1.69E+08 1.67E+08 - - - 5.0302 1 221125_WJC_METTL3_EV_vs_WT_F05.08439.08439.2 4.19E-07 18/24 K.EGVVHGVATVAEK[136.11].T "sp|P37840|SYUA_HUMAN,tr|A0A669KB41|A0A669KB41_HUMAN,tr|D6RA31|D6RA31_HUMAN,tr|A0A669KBH5|A0A669KBH5_HUMAN,tr|E7EPV7|E7EPV7_HUMAN" 5 1302.7023 1.52 61244 8439 2 1302.698119 652.3584 Alpha-synuclein OS=Homo sapiens OX=9606 GN=SNCA PE=1 SV=1 5.4 1924.4 - 2.62E+06 - - - -3.221 - 3.162 0.554 - 1386.6 1 2 0 -0.0042 13 0 0 0 7.98E+08 5.27E+08 - - - 6.0861 1 221125_WJC_METTL3_EV_vs_WT_F05.08440.08440.2 1.48E-07 20/24 K.EGVVHGVATVAEK.T "sp|P37840|SYUA_HUMAN,tr|A0A669KB41|A0A669KB41_HUMAN,tr|D6RA31|D6RA31_HUMAN,tr|A0A669KBH5|A0A669KBH5_HUMAN,tr|E7EPV7|E7EPV7_HUMAN" 5 1294.6881 1.52 61245 8440 2 1294.685506 648.3513 Alpha-synuclein OS=Homo sapiens OX=9606 GN=SNCA PE=1 SV=1 5.4 1924.5 - 2.92E+06 - - - -2.0152 - 3.486 0.544 - 2012.6 1 2 0 -0.0026 13 0 0 0 7.98E+08 5.27E+08 - - - 6.2631 0.9996 221125_WJC_METTL3_EV_vs_WT_F05.08445.08445.2 1.24E-05 16-Sep K.AQYEDIAQK.S sp|P04264|K2C1_HUMAN 1 1064.5138 999 61248 8445 2 1064.516195 533.2642 "Keratin, type II cytoskeletal 1 OS=Homo sapiens OX=9606 GN=KRT1 PE=1 SV=6" 4.37 1925.2 - 1.83E+06 - - - 2.2132 - 1.879 0.481 - 382.6 1 2 0 0.0024 9 0 0 0 8.13E+07 0.00E+00 - - - 4.4177 0.9884 221125_WJC_METTL3_EV_vs_WT_F05.08458.08458.2 1.32E-05 13/18 Q.YAQVLAQQQK.A "sp|Q6Y7W6|GGYF2_HUMAN,tr|A0A7I2V3H7|A0A7I2V3H7_HUMAN,tr|I1E4Y6|I1E4Y6_HUMAN,tr|A0A7I2V516|A0A7I2V516_HUMAN,tr|A0A7I2V3H0|A0A7I2V3H0_HUMAN,tr|C9JHW1|C9JHW1_HUMAN,tr|A0A7I2V361|A0A7I2V361_HUMAN,tr|E7ESB6|E7ESB6_HUMAN" 8 1175.6299 10.18 61254 8458 2 1175.629822 588.8222 GRB10-interacting GYF protein 2 OS=Homo sapiens OX=9606 GN=GIGYF2 PE=1 SV=1 8.59 1926.9 - 942559 - - - -0.0425 - 2.188 0.39 - 726 1 1 0 -0.0001 10 0 0 0 3.16E+07 3.10E+06 - - - 4.1071 0.9999 221125_WJC_METTL3_EV_vs_WT_F05.08462.08462.2 0.00335 16-Dec K.DTGHIYAMK.L "sp|Q9Y2H1|ST38L_HUMAN,tr|F5GY51|F5GY51_HUMAN,tr|I3L0D0|I3L0D0_HUMAN,tr|F5H277|F5H277_HUMAN" 4 1034.4855 3.84 61255 8462 2 1034.485598 518.25 Serine\threonine-protein kinase 38-like OS=Homo sapiens OX=9606 GN=STK38L PE=1 SV=3 6.74 1927.4 - 1.87E+06 - - - 0.0793 - 2.57 0.472 - 791.3 1 2 0 0.0001 9 0 0 0 6.87E+07 1.79E+07 - - - 5.2579 0.9998 221125_WJC_METTL3_EV_vs_WT_F05.08466.08466.2 0.000488 20-Dec R.SGQVLEVSGSK.A "sp|P21281|VATB2_HUMAN,tr|H0YC04|H0YC04_HUMAN" 2 1089.5666 1.31 61256 8466 2 1089.566566 545.7906 "V-type proton ATPase subunit B, brain isoform OS=Homo sapiens OX=9606 GN=ATP6V1B2 PE=1 SV=3" 5.72 1928 - 1.08E+06 - - - -0.034 - 2.257 0.423 - 420.9 1 2 0 0 11 0 0 0 3.63E+07 2.78E+07 - - - 4.3674 0.9992 221125_WJC_METTL3_EV_vs_WT_F05.08468.08468.2 2.35E-05 16-Sep R.QVSDDLTER.A "sp|P35232|PHB_HUMAN,tr|C9JZ20|C9JZ20_HUMAN,tr|E7ESE2|E7ESE2_HUMAN,tr|E9PCW0|E9PCW0_HUMAN,tr|C9JW96|C9JW96_HUMAN" 5 1061.4989 1.36 61257 8468 2 1061.495637 531.7567 Prohibitin OS=Homo sapiens OX=9606 GN=PHB PE=1 SV=1 4.03 1928.2 - 2.72E+06 - - - -3.09 - 1.707 0.504 - 378.4 1 2 0 -0.0033 9 0 0 0 2.80E+08 2.05E+08 - - - 4.3095 0.9998 221125_WJC_METTL3_EV_vs_WT_F05.08472.08472.2 0.000145 16-Nov R.QVSDDLTER[166.11].A "sp|P35232|PHB_HUMAN,tr|C9JZ20|C9JZ20_HUMAN,tr|E7ESE2|E7ESE2_HUMAN,tr|E9PCW0|E9PCW0_HUMAN,tr|C9JW96|C9JW96_HUMAN" 5 1071.5072 1.36 61259 8472 2 1071.507811 536.7609 Prohibitin OS=Homo sapiens OX=9606 GN=PHB PE=1 SV=1 4.03 1928.6 - 2.20E+06 - - - 0.5824 - 1.858 0.425 - 640.4 1 2 0 0.0006 9 0 0 0 2.80E+08 2.05E+08 - - - 3.9721 0.9997 221125_WJC_METTL3_EV_vs_WT_F05.08476.08476.2 0.00261 14-Sep K.YTC[160.03]SFC[160.03]GK[136.11].T "sp|P61513|RL37A_HUMAN,sp|A6NKH3|RL37L_HUMAN,tr|E9PEL3|E9PEL3_HUMAN,tr|G5E9R3|G5E9R3_HUMAN,tr|C9J4Z3|C9J4Z3_HUMAN,tr|M0R2L6|M0R2L6_HUMAN,tr|M0R0A1|M0R0A1_HUMAN,tr|Q6P4E4|Q6P4E4_HUMAN" 8 1029.4139 0.91 61261 8476 2 1029.414993 515.7142 60S ribosomal protein L37a OS=Homo sapiens OX=9606 GN=RPL37A PE=1 SV=2 8.05 1929.2 - 1.78E+06 - - - 1.0249 - 1.708 0.472 - 269.1 1 2 0 0.0011 8 0 0 0 1.48E+08 1.62E+08 - - - 4.1414 0.9995 221125_WJC_METTL3_EV_vs_WT_F05.08484.08484.2 0.0286 14/14 K.RFEGLTAR.G sp|Q15208|STK38_HUMAN 1 948.5141 3.18 61264 8484 2 948.512411 475.2643 Serine\threonine-protein kinase 38 OS=Homo sapiens OX=9606 GN=STK38 PE=1 SV=1 9.6 1930.2 - 1.82E+06 - - - -1.7954 - 2.047 0.329 - 483.6 1 2 0 -0.0017 8 0 0 0 3.39E+08 1.06E+08 - - - 3.631 0.9995 221125_WJC_METTL3_EV_vs_WT_F05.08485.08485.2 0.00965 16-Sep R.SQEQEVLER.G "sp|Q9UKV3|ACINU_HUMAN,tr|S4R3H4|S4R3H4_HUMAN,tr|E7EQT4|E7EQT4_HUMAN" 3 1116.5411 1.05 61265 8485 2 1116.539999 559.2778 Apoptotic chromatin condensation inducer in the nucleus OS=Homo sapiens OX=9606 GN=ACIN1 PE=1 SV=2 4.25 1930.4 - 1.65E+06 - - - -1.0013 - 1.912 0.321 - 433 1 2 0 -0.0011 9 0 0 0 7.31E+07 6.98E+07 - - - 3.2867 0.9989 221125_WJC_METTL3_EV_vs_WT_F05.08489.08489.2 0.0302 16-Jun R.NNFEGEVTK[136.11].E "sp|P07237|PDIA1_HUMAN,tr|A0A7P0TA97|A0A7P0TA97_HUMAN,tr|A0A7P0T8C0|A0A7P0T8C0_HUMAN,tr|H7BZ94|H7BZ94_HUMAN,tr|A0A7P0TA71|A0A7P0TA71_HUMAN,tr|I3L4M2|I3L4M2_HUMAN,tr|A0A7P0T9D6|A0A7P0T9D6_HUMAN,tr|A0A7P0T9K9|A0A7P0T9K9_HUMAN,tr|H0Y3Z3|H0Y3Z3_HUMAN,tr|A0A7P0Z4S2|A0A7P0Z4S2_HUMAN,tr|A0A7P0TA35|A0A7P0TA35_HUMAN,tr|I3L514|I3L514_HUMAN,tr|A0A7P0TB26|A0A7P0TB26_HUMAN,tr|A0A7P0T9U6|A0A7P0T9U6_HUMAN,tr|I3L0S0|I3L0S0_HUMAN,tr|I3L3P5|I3L3P5_HUMAN,tr|A0A7P0T8J3|A0A7P0T8J3_HUMAN,tr|A0A7P0Z4J0|A0A7P0Z4J0_HUMAN,tr|A0A7P0T8X1|A0A7P0T8X1_HUMAN" 19 1044.4967 1.35 61267 8489 2 1044.496501 523.2556 Protein disulfide-isomerase OS=Homo sapiens OX=9606 GN=P4HB PE=1 SV=3 4.53 1930.9 - 976410 - - - -0.2279 - 1.634 0.252 - 202.9 1 2 0 -0.0002 9 0 0 0 1.91E+08 1.41E+08 - - - 2.3228 0.8101 221125_WJC_METTL3_EV_vs_WT_F05.08490.08490.2 0.171 12-Oct L.R[166.11]DELDLR[166.11].R "sp|O95995|DRC4_HUMAN,tr|A0A087WZT7|A0A087WZT7_HUMAN" 2 935.4939 0.9 61268 8490 2 935.494535 468.7542 Dynein regulatory complex subunit 4 OS=Homo sapiens OX=9606 GN=GAS8 PE=1 SV=1 4.56 1931 - 929000 - - - 0.6424 - 1.754 0.076 - 441.6 1 1 0 0.0006 7 0 0 0 2.72E+07 3.03E+07 - - - 1.3826 0.9995 221125_WJC_METTL3_EV_vs_WT_F05.08491.08491.2 0.000378 14-Sep K.YTC[160.03]SFC[160.03]GK.T "sp|P61513|RL37A_HUMAN,sp|A6NKH3|RL37L_HUMAN,tr|E9PEL3|E9PEL3_HUMAN,tr|G5E9R3|G5E9R3_HUMAN,tr|C9J4Z3|C9J4Z3_HUMAN,tr|M0R2L6|M0R2L6_HUMAN,tr|M0R0A1|M0R0A1_HUMAN,tr|Q6P4E4|Q6P4E4_HUMAN" 8 1021.3997 0.91 61269 8491 2 1021.396446 511.7071 60S ribosomal protein L37a OS=Homo sapiens OX=9606 GN=RPL37A PE=1 SV=2 8.05 1931.1 - 2.79E+06 - - - -3.223 - 1.517 0.658 - 280.7 1 2 0 -0.0033 8 0 0 0 1.48E+08 1.62E+08 - - - 5.1568 0.9996 221125_WJC_METTL3_EV_vs_WT_F05.08492.08492.2 0.00664 16-Sep R.SQEQEVLER[166.11].G "sp|Q9UKV3|ACINU_HUMAN,tr|S4R3H4|S4R3H4_HUMAN,tr|E7EQT4|E7EQT4_HUMAN" 3 1126.5494 1.52 61270 8492 2 1126.549257 564.282 Apoptotic chromatin condensation inducer in the nucleus OS=Homo sapiens OX=9606 GN=ACIN1 PE=1 SV=2 4.25 1931.2 - 1.48E+06 - - - -0.1154 - 2.219 0.275 - 498.7 1 2 0 -0.0001 9 0 0 0 7.12E+07 4.69E+07 - - - 3.378 0.9842 221125_WJC_METTL3_EV_vs_WT_F05.08498.08498.2 0.000912 13/20 F.LEQQNQVLQTK.W "sp|Q7Z794|K2C1B_HUMAN,sp|P04264|K2C1_HUMAN,sp|P35908|K22E_HUMAN" 3 1327.7096 999 61274 8498 2 1327.706489 664.8621 "Keratin, type II cytoskeletal 1b OS=Homo sapiens OX=9606 GN=KRT77 PE=1 SV=3" 6 1932 - 2.08E+06 - - - -2.3273 - 2.731 0.477 - 849 1 1 0 -0.0031 11 0 0 0 4.29E+07 0.00E+00 - - - 5.281 0.9995 221125_WJC_METTL3_EV_vs_WT_F05.08501.08501.2 0.00375 14-Dec K.R[166.11]FEGLTAR[166.11].G sp|Q15208|STK38_HUMAN 1 968.5307 3.18 61275 8501 2 968.52895 485.2726 Serine\threonine-protein kinase 38 OS=Homo sapiens OX=9606 GN=STK38 PE=1 SV=1 9.6 1932.4 - 2.70E+06 - - - -1.7594 - 2.139 0.305 - 350 1 2 0 -0.0017 8 0 0 0 3.38E+08 1.06E+08 - - - 3.5863 0.9484 221125_WJC_METTL3_EV_vs_WT_F05.08504.08504.2 0.222 14-Jul R.NLGVHISR.V "sp|Q8IYB5|SMAP1_HUMAN,sp|Q8WU79|SMAP2_HUMAN,tr|A0A087WV97|A0A087WV97_HUMAN,tr|A0A087X1X9|A0A087X1X9_HUMAN,tr|X6RCC3|X6RCC3_HUMAN" 5 894.5035 1.01 61278 8504 2 894.500307 448.2591 Stromal membrane-associated protein 1 OS=Homo sapiens OX=9606 GN=SMAP1 PE=1 SV=2 9.76 1932.6 - 1.49E+06 - - - -3.6244 - 1.451 0.087 - 188.2 1 2 0 -0.0032 8 0 0 0 2.36E+07 2.33E+07 - - - 0.8053 0.9462 221125_WJC_METTL3_EV_vs_WT_F05.08507.08507.2 0.187 14-Sep R.QVNITVQK[136.11].K "sp|Q9P035|HACD3_HUMAN,tr|H3BPZ1|H3BPZ1_HUMAN,tr|H3BS72|H3BS72_HUMAN" 3 936.5484 0.9 61281 8507 2 936.543401 469.2815 Very-long-chain (3R)-3-hydroxyacyl-CoA dehydratase 3 OS=Homo sapiens OX=9606 GN=HACD3 PE=1 SV=2 8.75 1933 - 1.10E+06 - - - -5.3174 - 1.559 0.174 - 224.3 1 2 0 -0.005 8 0 0 0 2.37E+07 2.64E+07 - - - 1.6638 0.9266 221125_WJC_METTL3_EV_vs_WT_F05.08513.08513.2 0.000578 16-Dec R.PGFSIADKK.R "sp|P62913|RL11_HUMAN,tr|Q5VVC8|Q5VVC8_HUMAN" 2 961.5233 1.06 61285 8513 2 961.519509 481.7689 60S ribosomal protein L11 OS=Homo sapiens OX=9606 GN=RPL11 PE=1 SV=2 9.01 1933.7 - 1.24E+06 - - - -3.924 - 2.28 0.417 - 466.4 1 1 0 -0.0038 9 0 0 0 3.36E+07 3.19E+07 - - - 4.5042 0.9936 221125_WJC_METTL3_EV_vs_WT_F05.08514.08514.2 0.59 18-Aug K.AQEPSAAIPK.V sp|Q15459|SF3A1_HUMAN 1 1010.5397 1.09 61286 8514 2 1010.539939 506.2771 Splicing factor 3A subunit 1 OS=Homo sapiens OX=9606 GN=SF3A1 PE=1 SV=1 6.05 1933.8 - 588065 - - - 0.2761 - 1.479 0.128 - 247.3 2 2 0 0.0003 10 0 0 0 3.03E+07 2.77E+07 - - - 0.9443 0.9978 221125_WJC_METTL3_EV_vs_WT_F05.08518.08518.2 0.0341 14-Aug R.QVNITVQK.K "sp|Q9P035|HACD3_HUMAN,tr|H3BPZ1|H3BPZ1_HUMAN,tr|H3BS72|H3BS72_HUMAN" 3 928.5342 0.9 61288 8518 2 928.532956 465.2744 Very-long-chain (3R)-3-hydroxyacyl-CoA dehydratase 3 OS=Homo sapiens OX=9606 GN=HACD3 PE=1 SV=2 8.75 1934.4 - 1.75E+06 - - - -1.3193 - 1.653 0.195 - 323.9 1 2 0 -0.0012 8 0 0 0 2.37E+07 2.64E+07 - - - 1.9967 0.9979 221125_WJC_METTL3_EV_vs_WT_F05.08519.08519.3 1.38E-05 13/40 K.ITK[136.11]PDGIVEER[166.11].R "sp|O00165|HAX1_HUMAN,tr|Q5VYD6|Q5VYD6_HUMAN,tr|E9PIQ7|E9PIQ7_HUMAN" 3 1273.6997 1.69 61289 8519 3 1273.694836 425.5738 HCLS1-associated protein X-1 OS=Homo sapiens OX=9606 GN=HAX1 PE=1 SV=2 4.68 1934.5 - 1.84E+06 - - - -3.8078 - 2.18 0.309 - 208.1 1 2 0 -0.0049 11 0 0 0 1.40E+08 8.27E+07 - - - 4.1976 0.9987 221125_WJC_METTL3_EV_vs_WT_F05.08520.08520.2 0.229 12-Jul R.K[136.11]LPDLEK[136.11].T sp|Q9NX62|IMPA3_HUMAN 1 857.5193 1.23 61290 8520 2 857.519413 429.7669 "Golgi-resident adenosine 3',5'-bisphosphate 3'-phosphatase OS=Homo sapiens OX=9606 GN=BPNT2 PE=1 SV=1" 6.07 1934.6 - 1.50E+06 - - - 0.1096 - 1.755 0.181 - 224.2 1 2 0 0.0001 7 0 0 0 3.75E+07 3.05E+07 - - - 2.1601 0.7702 221125_WJC_METTL3_EV_vs_WT_F05.08521.08521.2 6.71E-05 18-Oct G.QAGAISITSK[136.11].A sp|Q9H3S7|PTN23_HUMAN 1 982.5539 1.87 61291 8521 2 982.553292 492.2842 Tyrosine-protein phosphatase non-receptor type 23 OS=Homo sapiens OX=9606 GN=PTPN23 PE=1 SV=1 8.75 1934.7 - 724936 - - - -0.5781 - 1.941 0.052 - 431.9 2 1 0 -0.0006 10 0 0 0 6.07E+07 3.25E+07 - - - 1.1416 1 221125_WJC_METTL3_EV_vs_WT_F05.08526.08526.2 8.58E-10 15/18 K.C[160.03]PTPC[160.03]QTYVK.C sp|Q5T750|XP32_HUMAN 1 1252.558 10.42 61294 8526 2 1252.554298 627.2863 Skin-specific protein 32 OS=Homo sapiens OX=9606 GN=XP32 PE=1 SV=1 8.05 1935.4 - 1.30E+06 - - - -2.9795 - 2.66 0.617 - 1177.3 1 2 0 -0.0037 10 0 0 0 3.34E+07 3.20E+06 - - - 6.3278 0.9889 221125_WJC_METTL3_EV_vs_WT_F05.08529.08529.2 0.0534 18-Aug K.LK[136.11]ETAESVLK[136.11].K "sp|P34932|HSP74_HUMAN,tr|A0A087WTS8|A0A087WTS8_HUMAN,tr|A0A087WYC1|A0A087WYC1_HUMAN" 3 1132.6674 0.09 61295 8529 2 1132.665277 567.341 Heat shock 70 kDa protein 4 OS=Homo sapiens OX=9606 GN=HSPA4 PE=1 SV=4 6.14 1935.8 - 3.73E+06 - - - -1.9097 - 1.71 0.338 - 101.9 1 2 1 -0.0022 10 0 0 0 6.92E+06 7.96E+07 - - - 3.0343 0.9981 221125_WJC_METTL3_EV_vs_WT_F05.08530.08530.2 0.000339 18-Oct K.STC[160.03]IYGGAPK.G "sp|Q92841|DDX17_HUMAN,sp|P17844|DDX5_HUMAN,tr|A0A7I2V5F5|A0A7I2V5F5_HUMAN,tr|J3KRZ1|J3KRZ1_HUMAN,tr|A0A7I2V507|A0A7I2V507_HUMAN,tr|A0A5H1ZRQ2|A0A5H1ZRQ2_HUMAN,tr|J3KTA4|J3KTA4_HUMAN,tr|A0A0G2JLI4|A0A0G2JLI4_HUMAN,tr|A0A1X7SBZ2|A0A1X7SBZ2_HUMAN,tr|A0A7I2V2S0|A0A7I2V2S0_HUMAN,tr|J3QRQ7|J3QRQ7_HUMAN" 11 1052.4961 1.39 61296 8530 2 1052.492259 527.2553 Probable ATP-dependent RNA helicase DDX17 OS=Homo sapiens OX=9606 GN=DDX17 PE=1 SV=2 7.92 1935.9 - 1.69E+06 - - - -3.6314 - 1.832 0.4 - 435 1 2 0 -0.0038 10 0 0 0 2.42E+08 1.74E+08 - - - 3.6841 0.9989 221125_WJC_METTL3_EV_vs_WT_F05.08531.08531.2 0.0295 16-Jul K.AAIAQLNGK.E sp|Q96PK6|RBM14_HUMAN 1 884.508 2.2 61297 8531 2 884.508825 443.2613 RNA-binding protein 14 OS=Homo sapiens OX=9606 GN=RBM14 PE=1 SV=2 8.8 1936 - 1.99E+06 - - - 0.9712 - 1.459 0.322 - 129.7 1 2 0 0.0009 9 0 0 0 4.59E+07 2.09E+07 - - - 2.5119 0.9994 221125_WJC_METTL3_EV_vs_WT_F05.08533.08533.2 0.00746 16-Sep K.AAIAQLNGK[136.11].E sp|Q96PK6|RBM14_HUMAN 1 892.5222 2.21 61299 8533 2 892.521423 447.2684 RNA-binding protein 14 OS=Homo sapiens OX=9606 GN=RBM14 PE=1 SV=2 8.8 1936.2 - 1.41E+06 - - - -0.8325 - 1.867 0.292 - 219.7 1 2 0 -0.0007 9 0 0 0 4.63E+07 2.09E+07 - - - 3.0037 0.9442 221125_WJC_METTL3_EV_vs_WT_F05.08534.08534.2 0.0272 20-Aug K.GGPTPQEAIQR[166.11].L sp|Q9H444|CHM4B_HUMAN 1 1162.597 5.8 61300 8534 2 1162.592941 582.3058 Charged multivesicular body protein 4b OS=Homo sapiens OX=9606 GN=CHMP4B PE=1 SV=1 6 1936.3 - 655900 - - - -3.4965 - 1.585 0.083 - 147.5 3 2 0 -0.0041 11 0 0 0 7.26E+07 1.25E+07 - - - 0.6856 0.9969 221125_WJC_METTL3_EV_vs_WT_F05.08538.08538.2 0.224 14-Aug R.R[166.11]GEFC[160.03]IAK[136.11].F "sp|Q7KZF4|SND1_HUMAN,tr|H7C597|H7C597_HUMAN" 2 997.5134 0.97 61302 8538 2 997.511175 499.764 Staphylococcal nuclease domain-containing protein 1 OS=Homo sapiens OX=9606 GN=SND1 PE=1 SV=1 8.22 1936.8 - 935809 - - - -2.2366 - 1.72 0.207 - 306.6 1 2 0 -0.0022 8 0 0 0 1.37E+07 1.41E+07 - - - 2.2048 0.9982 221125_WJC_METTL3_EV_vs_WT_F05.08539.08539.2 0.336 12-Jun R.DVYHLNR[166.11].H "sp|Q14119|VEZF1_HUMAN,sp|P56270|MAZ_HUMAN,sp|Q9HBE1|PATZ1_HUMAN,tr|J3QSH4|J3QSH4_HUMAN,tr|I3L2Z5|I3L2Z5_HUMAN,tr|A0A087WWR2|A0A087WWR2_HUMAN" 6 925.4645 1.09 61303 8539 2 925.464003 463.7395 Vascular endothelial zinc finger 1 OS=Homo sapiens OX=9606 GN=VEZF1 PE=1 SV=2 6.74 1936.9 - 2.73E+06 - - - -0.5748 - 1.189 0.312 - 205.6 1 2 0 -0.0005 7 0 0 0 8.76E+07 8.05E+07 - - - 1.8938 0.9293 221125_WJC_METTL3_EV_vs_WT_F05.08540.08540.2 0.0975 12-Jun R.DVYHLNR.H "sp|Q14119|VEZF1_HUMAN,sp|P56270|MAZ_HUMAN,sp|Q9HBE1|PATZ1_HUMAN,tr|J3QSH4|J3QSH4_HUMAN,tr|I3L2Z5|I3L2Z5_HUMAN,tr|A0A087WWR2|A0A087WWR2_HUMAN" 6 915.4563 1.09 61304 8540 2 915.451623 458.7354 Vascular endothelial zinc finger 1 OS=Homo sapiens OX=9606 GN=VEZF1 PE=1 SV=2 6.74 1936.9 - 2.22E+06 - - - -5.0707 - 1.074 0.277 - 212.3 1 2 0 -0.0046 7 0 0 0 8.76E+07 8.05E+07 - - - 1.3117 1 221125_WJC_METTL3_EV_vs_WT_F05.08541.08541.2 7.44E-08 14/24 K.EVASNSELVQSSR.S "sp|P08779|K1C16_HUMAN,tr|K7ENW6|K7ENW6_HUMAN" 2 1404.6845 999 61305 8541 2 1404.680979 703.3495 "Keratin, type I cytoskeletal 16 OS=Homo sapiens OX=9606 GN=KRT16 PE=1 SV=4" 4.53 1937.1 - 1.10E+06 - - - -2.4966 - 2.909 0.65 - 807.7 1 2 0 -0.0035 13 0 0 0 5.16E+07 0.00E+00 - - - 6.5814 0.9996 221125_WJC_METTL3_EV_vs_WT_F05.08545.08545.2 0.00316 20-Jul K.ITK[136.11]PDGIVEER[166.11].R "sp|O00165|HAX1_HUMAN,tr|Q5VYD6|Q5VYD6_HUMAN,tr|E9PIQ7|E9PIQ7_HUMAN" 3 1273.6997 1.66 61309 8545 2 1273.698769 637.8571 HCLS1-associated protein X-1 OS=Homo sapiens OX=9606 GN=HAX1 PE=1 SV=2 4.68 1937.6 - 626196 - - - -0.7199 - 1.389 0.473 - 113.7 1 2 0 -0.0009 11 0 0 0 1.34E+07 8.07E+06 - - - 3.4232 0.9937 221125_WJC_METTL3_EV_vs_WT_F05.08550.08550.2 7.91E-05 18-Oct L.EESNYELEGK.L "sp|P13645|K1C10_HUMAN,tr|A0A1B0GVI3|A0A1B0GVI3_HUMAN" 2 1196.5197 689.96 61312 8550 2 1196.519397 599.2671 "Keratin, type I cytoskeletal 10 OS=Homo sapiens OX=9606 GN=KRT10 PE=1 SV=6" 4.09 1938.2 - 6.17E+06 - - - -0.2641 - 2.082 0.545 - 468.7 1 1 0 -0.0003 10 0 0 0 9.13E+07 1.32E+05 - - - 5.1132 1 221125_WJC_METTL3_EV_vs_WT_F05.08551.08551.3 6.44E-06 Dec-40 K.ITKPDGIVEER.R "sp|O00165|HAX1_HUMAN,tr|Q5VYD6|Q5VYD6_HUMAN,tr|E9PIQ7|E9PIQ7_HUMAN" 3 1255.6772 1.7 61313 8551 3 1255.675148 419.5663 HCLS1-associated protein X-1 OS=Homo sapiens OX=9606 GN=HAX1 PE=1 SV=2 4.68 1938.3 - 5.99E+06 - - - -1.6469 - 2.426 0.544 - 243.4 1 2 0 -0.0021 11 0 0 0 1.40E+08 8.27E+07 - - - 7.1222 1 221125_WJC_METTL3_EV_vs_WT_F05.08552.08552.3 0.000759 Dec-44 K.EAPPMEKPEVVK.T "sp|P62841|RS15_HUMAN,tr|K7EJ78|K7EJ78_HUMAN,tr|K7EM56|K7EM56_HUMAN,tr|A0A0B4J2B4|A0A0B4J2B4_HUMAN,tr|S4R456|S4R456_HUMAN,tr|K7ELC2|K7ELC2_HUMAN,tr|K7EQJ5|K7EQJ5_HUMAN,tr|S4R417|S4R417_HUMAN" 8 1352.701 1.36 61314 8552 3 1352.699139 451.9076 40S ribosomal protein S15 OS=Homo sapiens OX=9606 GN=RPS15 PE=1 SV=2 4.79 1938.4 - 3.17E+06 - - - -1.3669 - 2.734 0.48 - 231.6 1 2 0 -0.0018 12 0 0 0 1.32E+09 9.75E+08 - - - 6.6788 0.9997 221125_WJC_METTL3_EV_vs_WT_F05.08554.08554.2 1.18E-05 16-Oct R.DPSQQELPR[166.11].L "sp|P49327|FAS_HUMAN,tr|A0A0U1RQF0|A0A0U1RQF0_HUMAN" 2 1078.5283 0.7 61316 8554 2 1078.528939 540.2714 Fatty acid synthase OS=Homo sapiens OX=9606 GN=FASN PE=1 SV=3 4.37 1938.5 - 1.53E+06 - - - 0.6323 - 1.748 0.426 - 430 1 2 0 0.0007 9 0 0 0 6.60E+07 9.40E+07 - - - 3.8029 0.9995 221125_WJC_METTL3_EV_vs_WT_F05.08555.08555.2 0.00366 20-Oct K.ETGQQIGDEVR[166.11].A "sp|Q9GZT9|EGLN1_HUMAN,tr|A0A590UJ78|A0A590UJ78_HUMAN" 2 1240.5923 0.18 61317 8555 2 1240.590428 621.3034 Egl nine homolog 1 OS=Homo sapiens OX=9606 GN=EGLN1 PE=1 SV=1 4.14 1938.6 - 1.11E+06 - - - -1.5202 - 2.097 0.326 - 407.7 1 2 0 -0.0019 11 0 0 0 2.83E+06 1.62E+07 - - - 3.4515 0.88 221125_WJC_METTL3_EV_vs_WT_F05.08557.08557.3 0.892 Nov-36 R.WLQQEEEERR.H sp|Q9NQS7|INCE_HUMAN 1 1401.6637 1.13 61319 8557 3 1401.666381 468.2285 Inner centromere protein OS=Homo sapiens OX=9606 GN=INCENP PE=1 SV=3 4.49 1938.9 - 550540 - - - 1.9191 - 1.649 0.06 - 224.9 1 2 0 0.0027 10 0 0 0 1.07E+07 9.50E+06 - - - 0.6689 0.9997 221125_WJC_METTL3_EV_vs_WT_F05.08561.08561.2 1.81E-05 18-Sep K.STC[160.03]IYGGAPK[136.11].G "sp|Q92841|DDX17_HUMAN,sp|P17844|DDX5_HUMAN,tr|A0A7I2V5F5|A0A7I2V5F5_HUMAN,tr|J3KRZ1|J3KRZ1_HUMAN,tr|A0A7I2V507|A0A7I2V507_HUMAN,tr|A0A5H1ZRQ2|A0A5H1ZRQ2_HUMAN,tr|J3KTA4|J3KTA4_HUMAN,tr|A0A0G2JLI4|A0A0G2JLI4_HUMAN,tr|A0A1X7SBZ2|A0A1X7SBZ2_HUMAN,tr|A0A7I2V2S0|A0A7I2V2S0_HUMAN,tr|J3QRQ7|J3QRQ7_HUMAN" 11 1060.5103 1.39 61321 8561 2 1060.508314 531.2624 Probable ATP-dependent RNA helicase DDX17 OS=Homo sapiens OX=9606 GN=DDX17 PE=1 SV=2 7.92 1939.4 - 4.94E+06 - - - -1.8548 - 1.67 0.563 - 305 1 2 0 -0.002 10 0 0 0 2.42E+08 1.74E+08 - - - 4.6301 0.9998 221125_WJC_METTL3_EV_vs_WT_F05.08565.08565.2 5.54E-06 16-Oct R.DPSQQELPR.L "sp|P49327|FAS_HUMAN,tr|A0A0U1RQF0|A0A0U1RQF0_HUMAN" 2 1068.52 0.69 61325 8565 2 1068.520595 535.2673 Fatty acid synthase OS=Homo sapiens OX=9606 GN=FASN PE=1 SV=3 4.37 1939.7 - 1.19E+06 - - - 0.569 - 2.002 0.404 - 623.7 1 2 0 0.0006 9 0 0 0 6.49E+07 9.39E+07 - - - 4.033 0.9812 221125_WJC_METTL3_EV_vs_WT_F05.08566.08566.2 0.919 20-Sep K.GGPTPQEAIQR.L sp|Q9H444|CHM4B_HUMAN 1 1152.5887 19.4 61326 8566 2 1152.585651 577.3016 Charged multivesicular body protein 4b OS=Homo sapiens OX=9606 GN=CHMP4B PE=1 SV=1 6 1939.9 - 1.04E+06 - - - -2.6766 - 1.518 0.119 - 236.4 1 2 0 -0.0031 11 0 0 0 5.11E+07 2.63E+06 - - - 1.0481 0.9994 221125_WJC_METTL3_EV_vs_WT_F05.08569.08569.2 0.00301 18-Jul R.EC[160.03]ELSPGVNR[166.11].D "sp|Q9BXP5|SRRT_HUMAN,tr|H7C3A1|H7C3A1_HUMAN" 2 1169.5374 1.06 61329 8569 2 1169.537896 585.776 Serrate RNA effector molecule homolog OS=Homo sapiens OX=9606 GN=SRRT PE=1 SV=1 4.53 1940.2 - 491673 - - - 0.3882 - 1.585 0.348 - 215.6 1 2 0 0.0005 10 0 0 0 1.19E+07 1.12E+07 - - - 2.8968 0.9998 221125_WJC_METTL3_EV_vs_WT_F05.08572.08572.2 0.000996 16-Sep K.ESEFDDEPK.F "sp|Q9Y2W1|TR150_HUMAN,tr|A0A3B3ITZ9|A0A3B3ITZ9_HUMAN" 2 1094.4404 2.86 61331 8572 2 1094.439887 548.2275 Thyroid hormone receptor-associated protein 3 OS=Homo sapiens OX=9606 GN=THRAP3 PE=1 SV=2 3.83 1940.6 - 1.07E+08 - - - -0.4687 - 1.612 0.507 - 332.1 1 2 0 -0.0005 9 0 0 0 2.29E+10 8.00E+09 - - - 4.1669 0.9984 221125_WJC_METTL3_EV_vs_WT_F05.08573.08573.2 0.144 12-Jul R.FSGVPDR.F "sp|A0A075B6R9|KVD24_HUMAN,sp|A0A0C4DH68|KV224_HUMAN,sp|A2NJV5|KV229_HUMAN,sp|A0A075B6S2|KVD29_HUMAN,sp|A0A0A0MRZ7|KVD26_HUMAN" 5 776.3817 307.96 61332 8573 2 776.380544 389.1981 Probable non-functional immunoglobulin kappa variable 2D-24 OS=Homo sapiens OX=9606 GN=IGKV2D-24 PE=1 SV=1 5.84 1940.7 - 1.48E+08 - - - -1.4928 - 1.518 0.27 - 162.7 1 2 0 -0.0012 7 0 0 0 2.23E+09 7.23E+06 - - - 2.3574 0.9998 221125_WJC_METTL3_EV_vs_WT_F05.08574.08574.2 0.00122 18-Oct K.AEAESLYQSK.Y sp|P04264|K2C1_HUMAN 1 1124.535 628.62 61333 8574 2 1124.533843 563.2748 "Keratin, type II cytoskeletal 1 OS=Homo sapiens OX=9606 GN=KRT1 PE=1 SV=6" 4.53 1940.7 - 9.48E+06 - - - -1.0013 - 1.877 0.516 - 401.3 1 2 0 -0.0011 10 0 0 0 4.69E+09 7.46E+06 - - - 4.6094 1 221125_WJC_METTL3_EV_vs_WT_F05.08575.08575.2 5.49E-09 15/24 R.EVATNSELVQSGK.S "sp|Q04695|K1C17_HUMAN,sp|P02533|K1C14_HUMAN,tr|K7ESE1|K7ESE1_HUMAN,tr|F5GWP8|F5GWP8_HUMAN" 4 1360.6834 999 61334 8575 2 1360.682421 681.349 "Keratin, type I cytoskeletal 17 OS=Homo sapiens OX=9606 GN=KRT17 PE=1 SV=2" 4.53 1940.8 - 2.11E+06 - - - -0.7371 - 2.937 0.626 - 764.3 1 2 0 -0.001 13 0 0 0 1.16E+10 0.00E+00 - - - 6.4295 0.9998 221125_WJC_METTL3_EV_vs_WT_F05.08576.08576.2 0.00232 16-Oct K.SAAMTLNER.F "sp|Q9NYF8|BCLF1_HUMAN,tr|E9PKI6|E9PKI6_HUMAN,tr|A0A1W2PQ43|A0A1W2PQ43_HUMAN,tr|E9PK91|E9PK91_HUMAN,tr|E9PK09|E9PK09_HUMAN,tr|E9PQN2|E9PQN2_HUMAN" 6 991.4757 0.97 61335 8576 2 991.474074 496.7451 Bcl-2-associated transcription factor 1 OS=Homo sapiens OX=9606 GN=BCLAF1 PE=1 SV=2 5.72 1940.8 - 1.67E+06 - - - -1.6198 - 2.169 0.437 - 487.3 1 2 0 -0.0016 9 0 0 0 8.32E+07 8.61E+07 - - - 4.5082 0.9796 221125_WJC_METTL3_EV_vs_WT_F05.08579.08579.2 0.000177 20-Aug K.R[166.11]GLLQDDAHPT.L "sp|Q86U44|MTA70_HUMAN,tr|F5H6D8|F5H6D8_HUMAN,tr|H0YFV6|H0YFV6_HUMAN,tr|B4DTN4|B4DTN4_HUMAN" 4 1231.6185 0.01 61338 8579 2 1231.617752 616.8165 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 5.21 1941.2 - 414639 - - - -0.5822 - 1.588 0.429 - 184.1 1 1 0 -0.0007 11 0 0 0 1.28E+06 9.69E+07 - - - 3.4605 0.9987 221125_WJC_METTL3_EV_vs_WT_F05.08581.08581.2 0.00133 22-Jul K.EAPPMEKPEVVK.T "sp|P62841|RS15_HUMAN,tr|K7EJ78|K7EJ78_HUMAN,tr|K7EM56|K7EM56_HUMAN,tr|A0A0B4J2B4|A0A0B4J2B4_HUMAN,tr|S4R456|S4R456_HUMAN,tr|K7ELC2|K7ELC2_HUMAN,tr|K7EQJ5|K7EQJ5_HUMAN,tr|S4R417|S4R417_HUMAN" 8 1352.701 1.44 61340 8581 2 1352.698599 677.3578 40S ribosomal protein S15 OS=Homo sapiens OX=9606 GN=RPS15 PE=1 SV=2 4.79 1941.5 - 369283 - - - -1.7661 - 1.528 0.34 - 85 1 2 0 -0.0024 12 0 0 0 8.20E+07 5.71E+07 - - - 2.667 0.9998 221125_WJC_METTL3_EV_vs_WT_F05.08583.08583.2 0.000163 16-Sep K.ESEFDDEPK[136.11].F "sp|Q9Y2W1|TR150_HUMAN,tr|A0A3B3ITZ9|A0A3B3ITZ9_HUMAN" 2 1102.4546 2.86 61341 8583 2 1102.453749 552.2346 Thyroid hormone receptor-associated protein 3 OS=Homo sapiens OX=9606 GN=THRAP3 PE=1 SV=2 3.83 1941.7 - 2.62E+07 - - - -0.7719 - 1.643 0.56 - 320.9 1 2 0 -0.0009 9 0 0 0 2.29E+10 8.00E+09 - - - 4.6134 0.98 221125_WJC_METTL3_EV_vs_WT_F05.08585.08585.3 0.000499 Aug-40 K.R[166.11]GLLQDDAHPT.L "sp|Q86U44|MTA70_HUMAN,tr|F5H6D8|F5H6D8_HUMAN,tr|H0YFV6|H0YFV6_HUMAN,tr|B4DTN4|B4DTN4_HUMAN" 4 1231.6185 0.03 61342 8585 3 1231.617912 411.5468 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 5.21 1941.9 - 1.99E+06 - - - -0.4523 - 1.639 0.417 - 92.8 1 1 0 -0.0006 11 0 0 0 5.84E+06 2.12E+08 - - - 4.5926 0.9997 221125_WJC_METTL3_EV_vs_WT_F05.08586.08586.2 0.000987 20-Oct K.IANPVEGSTDR.Q "sp|Q15366|PCBP2_HUMAN,tr|F8VRH0|F8VRH0_HUMAN,tr|F8VZX2|F8VZX2_HUMAN,tr|H3BRU6|H3BRU6_HUMAN,tr|H3BSS4|H3BSS4_HUMAN" 5 1157.5677 1.26 61343 8586 2 1157.568883 579.7911 Poly(rC)-binding protein 2 OS=Homo sapiens OX=9606 GN=PCBP2 PE=1 SV=1 4.37 1942 - 1.13E+06 - - - 1.0513 - 2.162 0.388 - 336.4 1 2 0 0.0012 11 0 0 0 6.63E+08 5.25E+08 - - - 3.9922 0.9876 221125_WJC_METTL3_EV_vs_WT_F05.08587.08587.2 0.201 12-Aug R.YKIENIR.R "sp|Q9Y5K5|UCHL5_HUMAN,tr|H0Y4K0|H0Y4K0_HUMAN,tr|H0Y4E0|H0Y4E0_HUMAN,tr|Q5LJA9|Q5LJA9_HUMAN,tr|H0Y636|H0Y636_HUMAN,tr|H0Y6Y4|H0Y6Y4_HUMAN,tr|Q5LJA5|Q5LJA5_HUMAN" 7 934.5236 1.64 61344 8587 2 934.52292 468.2691 Ubiquitin carboxyl-terminal hydrolase isozyme L5 OS=Homo sapiens OX=9606 GN=UCHL5 PE=1 SV=3 8.59 1942.1 - 1.01E+06 - - - -0.7448 - 1.759 0.205 - 229.5 1 2 1 -0.0007 7 0 0 0 9.30E+07 5.67E+07 - - - 2.3443 0.9998 221125_WJC_METTL3_EV_vs_WT_F05.08588.08588.2 0.00011 20-Dec K.IANPVEGSTDR[166.11].Q "sp|Q15366|PCBP2_HUMAN,tr|F8VRH0|F8VRH0_HUMAN,tr|F8VZX2|F8VZX2_HUMAN,tr|H3BRU6|H3BRU6_HUMAN,tr|H3BSS4|H3BSS4_HUMAN" 5 1167.5759 1.26 61345 8588 2 1167.575644 584.7952 Poly(rC)-binding protein 2 OS=Homo sapiens OX=9606 GN=PCBP2 PE=1 SV=1 4.37 1942.2 - 845960 - - - -0.2501 - 2.115 0.412 - 594.6 1 2 0 -0.0003 11 0 0 0 6.63E+08 5.25E+08 - - - 4.1103 1 221125_WJC_METTL3_EV_vs_WT_F05.08591.08591.2 1.82E-05 14/24 K.GPGEVAGTVTGQK[136.11].R "sp|Q86U44|MTA70_HUMAN,tr|F5H6D8|F5H6D8_HUMAN,tr|H0YFV6|H0YFV6_HUMAN,tr|B4DTN4|B4DTN4_HUMAN" 4 1207.6288 0.03 61347 8591 2 1207.628036 604.8217 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 6 1942.5 - 2.04E+07 - - - -0.6459 - 2.965 0.606 - 895.4 1 2 0 -0.0008 13 0 0 0 3.79E+09 1.37E+11 - - - 6.3062 0.9997 221125_WJC_METTL3_EV_vs_WT_F05.08593.08593.2 0.00113 16-Sep R.SDYDGIGSR[166.11].G "sp|O00571|DDX3X_HUMAN,tr|A0A2R8YFR4|A0A2R8YFR4_HUMAN,tr|A0A2R8YCW1|A0A2R8YCW1_HUMAN,tr|A0A2R8YDH3|A0A2R8YDH3_HUMAN,tr|A0A2R8Y645|A0A2R8Y645_HUMAN,tr|A0A2R8YF78|A0A2R8YF78_HUMAN,tr|A0A2R8YCU0|A0A2R8YCU0_HUMAN,tr|A0A0D9SFB3|A0A0D9SFB3_HUMAN,tr|A0A2R8YFS5|A0A2R8YFS5_HUMAN,tr|A0A0D9SF53|A0A0D9SF53_HUMAN,tr|A0A2R8Y650|A0A2R8Y650_HUMAN,tr|A0A2R8Y5G6|A0A2R8Y5G6_HUMAN,tr|A0A0D9SG12|A0A0D9SG12_HUMAN,tr|F6S8Q4|F6S8Q4_HUMAN,tr|A0A2U3TZJ9|A0A2U3TZJ9_HUMAN,tr|A0A2R8Y4A4|A0A2R8Y4A4_HUMAN,tr|A0A2R8YF89|A0A2R8YF89_HUMAN" 17 978.4282 4.07 61348 8593 2 978.426323 490.2214 ATP-dependent RNA helicase DDX3X OS=Homo sapiens OX=9606 GN=DDX3X PE=1 SV=3 4.21 1942.8 - 3.62E+06 - - - -1.9276 - 1.804 0.482 - 294.6 1 2 0 -0.0019 9 0 0 0 1.27E+09 3.11E+08 - - - 4.3074 0.9982 221125_WJC_METTL3_EV_vs_WT_F05.08595.08595.2 0.0345 14-Aug R.KAC[160.03]QIFVR.N "sp|P52272|HNRPM_HUMAN,tr|M0R2I7|M0R2I7_HUMAN,tr|M0QY96|M0QY96_HUMAN,tr|A0A087X0X3|A0A087X0X3_HUMAN" 4 1020.5539 2.18 61350 8595 2 1020.556752 511.2842 Heterogeneous nuclear ribonucleoprotein M OS=Homo sapiens OX=9606 GN=HNRNPM PE=1 SV=3 9.51 1942.8 - 2.44E+06 - - - 2.823 - 1.677 0.344 - 297.7 1 2 0 0.0029 8 0 0 0 6.14E+07 2.82E+07 - - - 3.1401 0.9992 221125_WJC_METTL3_EV_vs_WT_F05.08596.08596.2 0.0804 14-Aug R.K[136.11]AC[160.03]QIFVR[166.11].N "sp|P52272|HNRPM_HUMAN,tr|M0R2I7|M0R2I7_HUMAN,tr|M0QY96|M0QY96_HUMAN,tr|A0A087X0X3|A0A087X0X3_HUMAN" 4 1038.5763 2.18 61351 8596 2 1038.575615 520.2954 Heterogeneous nuclear ribonucleoprotein M OS=Homo sapiens OX=9606 GN=HNRNPM PE=1 SV=3 9.51 1942.9 - 1.64E+06 - - - -0.699 - 1.498 0.32 - 254.2 1 2 0 -0.0007 8 0 0 0 6.14E+07 2.82E+07 - - - 2.6231 0.9998 221125_WJC_METTL3_EV_vs_WT_F05.08598.08598.2 0.000183 16-Aug K.SSFTVDC[160.03]SK.A "sp|P21333|FLNA_HUMAN,tr|A0A7P0NMY4|A0A7P0NMY4_HUMAN,tr|Q60FE5|Q60FE5_HUMAN" 3 1029.4437 1.02 61353 8598 2 1029.444351 515.7291 Filamin-A OS=Homo sapiens OX=9606 GN=FLNA PE=1 SV=4 5.55 1943.1 - 890140 - - - 0.6217 - 1.615 0.534 - 214.1 1 2 0 0.0006 9 0 0 0 2.44E+07 2.38E+07 - - - 4.3717 0.9998 221125_WJC_METTL3_EV_vs_WT_F05.08600.08600.2 1.12E-05 22-Oct K.EAPPMEK[136.11]PEVVK[136.11].T "sp|P62841|RS15_HUMAN,tr|K7EJ78|K7EJ78_HUMAN,tr|K7EM56|K7EM56_HUMAN,tr|A0A0B4J2B4|A0A0B4J2B4_HUMAN,tr|S4R456|S4R456_HUMAN,tr|K7ELC2|K7ELC2_HUMAN,tr|K7EQJ5|K7EQJ5_HUMAN,tr|S4R417|S4R417_HUMAN" 8 1368.7294 1.45 61355 8600 2 1368.728126 685.372 40S ribosomal protein S15 OS=Homo sapiens OX=9606 GN=RPS15 PE=1 SV=2 4.79 1943.4 - 640057 - - - -0.922 - 2.067 0.48 - 224.3 1 2 0 -0.0013 12 0 0 0 8.06E+07 5.58E+07 - - - 4.4964 0.9989 221125_WJC_METTL3_EV_vs_WT_F05.08603.08603.2 0.144 18-Oct R.EQEITAVQAR.M "sp|Q9P2E9|RRBP1_HUMAN,tr|A0A087WVV2|A0A087WVV2_HUMAN,tr|F8W7S5|F8W7S5_HUMAN" 3 1143.5884 1.39 61356 8603 2 1143.589476 572.8015 Ribosome-binding protein 1 OS=Homo sapiens OX=9606 GN=RRBP1 PE=1 SV=5 4.53 1943.7 - 1.22E+07 - - - 0.94 - 1.72 0.267 - 274.1 1 2 0 0.0011 10 0 0 0 1.21E+08 8.70E+07 - - - 2.5265 0.9996 221125_WJC_METTL3_EV_vs_WT_F05.08604.08604.2 0.0118 14-Jun R.DGYQQNFK[136.11].R "sp|Q14444|CAPR1_HUMAN,tr|G3V153|G3V153_HUMAN" 2 1006.46 0.9 61357 8604 2 1006.459197 504.2373 Caprin-1 OS=Homo sapiens OX=9606 GN=CAPRIN1 PE=1 SV=2 5.83 1943.8 - 3.39E+06 - - - -0.7581 - 1.257 0.506 - 86.7 1 2 0 -0.0008 8 0 0 0 6.94E+08 7.72E+08 - - - 3.4679 0.9993 221125_WJC_METTL3_EV_vs_WT_F05.08605.08605.2 0.00652 14-Jul R.DGYQQNFK.R "sp|Q14444|CAPR1_HUMAN,tr|G3V153|G3V153_HUMAN" 2 998.4458 0.9 61358 8605 2 998.446246 500.2302 Caprin-1 OS=Homo sapiens OX=9606 GN=CAPRIN1 PE=1 SV=2 5.83 1943.9 - 2.65E+06 - - - 0.4868 - 1.289 0.405 - 114.8 1 2 0 0.0005 8 0 0 0 6.93E+08 7.71E+08 - - - 2.7978 0.9885 221125_WJC_METTL3_EV_vs_WT_F05.08606.08606.2 1.08 12-Sep R.YK[136.11]IENIR[166.11].R "sp|Q9Y5K5|UCHL5_HUMAN,tr|H0Y4K0|H0Y4K0_HUMAN,tr|H0Y4E0|H0Y4E0_HUMAN,tr|Q5LJA9|Q5LJA9_HUMAN,tr|H0Y636|H0Y636_HUMAN,tr|H0Y6Y4|H0Y6Y4_HUMAN,tr|Q5LJA5|Q5LJA5_HUMAN" 7 952.5461 1.64 61359 8606 2 952.545801 477.2803 Ubiquitin carboxyl-terminal hydrolase isozyme L5 OS=Homo sapiens OX=9606 GN=UCHL5 PE=1 SV=3 8.59 1944 - 2.02E+06 - - - -0.2992 - 1.875 0.177 - 282.9 1 2 1 -0.0003 7 0 0 0 9.30E+07 5.67E+07 - - - 2.34 0.9995 221125_WJC_METTL3_EV_vs_WT_F05.08607.08607.3 0.00071 Dec-48 R.EVATNSELVQSGK.S "sp|Q04695|K1C17_HUMAN,sp|P02533|K1C14_HUMAN,tr|K7ESE1|K7ESE1_HUMAN,tr|F5GWP8|F5GWP8_HUMAN" 4 1360.6834 999 61360 8607 3 1360.679956 454.5684 "Keratin, type I cytoskeletal 17 OS=Homo sapiens OX=9606 GN=KRT17 PE=1 SV=2" 4.53 1944 - 1.72E+06 - - - -2.5487 - 2.317 0.349 - 267.9 1 2 0 -0.0035 13 0 0 0 3.37E+08 0.00E+00 - - - 4.7083 0.9994 221125_WJC_METTL3_EV_vs_WT_F05.08608.08608.2 0.0023 16-Nov K.SFQQSSLSR.D "sp|P43243|MATR3_HUMAN,tr|A0A1B0GX04|A0A1B0GX04_HUMAN,tr|D6RBS2|D6RBS2_HUMAN,tr|A8MXP9|A8MXP9_HUMAN,tr|D6R991|D6R991_HUMAN,tr|D6REK4|D6REK4_HUMAN,tr|D6R9F3|D6R9F3_HUMAN,tr|A0A0R4J2E8|A0A0R4J2E8_HUMAN,tr|D6RB45|D6RB45_HUMAN,tr|D6RCM3|D6RCM3_HUMAN,tr|D6R8Z5|D6R8Z5_HUMAN,tr|D6REM6|D6REM6_HUMAN" 12 1038.5094 0.85 61361 8608 2 1038.508549 520.262 Matrin-3 OS=Homo sapiens OX=9606 GN=MATR3 PE=1 SV=2 9.47 1944.1 - 1.61E+06 - - - -0.8416 - 1.455 0.389 - 331.5 1 2 0 -0.0009 9 0 0 0 6.91E+07 8.17E+07 - - - 2.9988 0.9997 221125_WJC_METTL3_EV_vs_WT_F05.08615.08615.3 0.000507 16/36 R.LLEEANK[136.11]YEK[136.11].T "sp|Q15643|TRIPB_HUMAN,tr|H0YJ97|H0YJ97_HUMAN" 2 1251.6682 1.19 61366 8615 3 1251.666247 418.23 Thyroid receptor-interacting protein 11 OS=Homo sapiens OX=9606 GN=TRIP11 PE=1 SV=3 4.79 1945 - 5.60E+06 - - - -1.5348 - 2.865 0.383 - 499.5 1 2 1 -0.0019 10 0 0 0 3.26E+08 2.75E+08 - - - 5.8835 0.9973 221125_WJC_METTL3_EV_vs_WT_F05.08616.08616.3 0.187 Nov-40 K.AALSEEELEK[136.11]K[136.11].S "sp|Q04637|IF4G1_HUMAN,tr|E7EUU4|E7EUU4_HUMAN,tr|E9PGM1|E9PGM1_HUMAN,tr|E7EX73|E7EX73_HUMAN,tr|A0A7I2Y1C3|A0A7I2Y1C3_HUMAN" 5 1261.6736 1.14 61367 8616 3 1261.67225 421.5652 Eukaryotic translation initiation factor 4 gamma 1 OS=Homo sapiens OX=9606 GN=EIF4G1 PE=1 SV=4 4.49 1945.1 - 1.36E+06 - - - -1.1073 - 1.76 0.225 - 99.8 1 2 0 -0.0014 11 0 0 0 4.49E+07 3.96E+07 - - - 2.6541 0.9831 221125_WJC_METTL3_EV_vs_WT_F05.08617.08617.3 0.00354 13/44 M.SLGEPHAELDAK[136.11].G "sp|Q9NWS0|PIHD1_HUMAN,tr|M0QYF4|M0QYF4_HUMAN,tr|M0R3A4|M0R3A4_HUMAN,tr|M0R3A8|M0R3A8_HUMAN,tr|M0R028|M0R028_HUMAN,tr|M0QZM3|M0QZM3_HUMAN,tr|M0R1R3|M0R1R3_HUMAN,tr|M0QYA2|M0QYA2_HUMAN" 8 1273.6394 1.46 61368 8617 3 1273.638497 425.5537 PIH1 domain-containing protein 1 OS=Homo sapiens OX=9606 GN=PIH1D1 PE=1 SV=1 4.65 1945.1 - 1.35E+06 - - - -0.6941 - 2.04 0.379 - 170.1 1 1 0 -0.0009 12 0 0 0 8.13E+07 5.55E+07 - - - 4.7414 0.9996 221125_WJC_METTL3_EV_vs_WT_F05.08618.08618.2 0.00241 18-Sep K.DIPDC[160.03]PC[160.03]GAK.R "sp|Q16342|PDCD2_HUMAN,tr|F5H4V9|F5H4V9_HUMAN" 2 1131.4689 0.85 61369 8618 2 1131.468787 566.7417 Programmed cell death protein 2 OS=Homo sapiens OX=9606 GN=PDCD2 PE=1 SV=2 4.21 1945.3 - 966197 - - - -0.0822 - 1.344 0.445 - 260.6 1 2 0 -0.0001 10 0 0 0 2.84E+07 3.33E+07 - - - 3.153 0.9964 221125_WJC_METTL3_EV_vs_WT_F05.08619.08619.2 0.0224 18-Oct R.LLEEANK[136.11]YEK[136.11].T "sp|Q15643|TRIPB_HUMAN,tr|H0YJ97|H0YJ97_HUMAN" 2 1251.6682 1.36 61370 8619 2 1251.66687 626.8414 Thyroid receptor-interacting protein 11 OS=Homo sapiens OX=9606 GN=TRIP11 PE=1 SV=3 4.79 1945.4 - 842112 - - - -1.037 - 1.873 0.396 - 287.3 1 2 1 -0.0013 10 0 0 0 6.88E+07 5.06E+07 - - - 3.7171 0.9998 221125_WJC_METTL3_EV_vs_WT_F05.08624.08624.2 0.000538 13/20 R.NAITSSYSSTR[166.11].G "sp|Q96HA1|P121A_HUMAN,sp|A8CG34|P121C_HUMAN,tr|C9JFL1|C9JFL1_HUMAN" 3 1195.5709 1.19 61373 8624 2 1195.569154 598.7927 Nuclear envelope pore membrane protein POM 121 OS=Homo sapiens OX=9606 GN=POM121 PE=1 SV=2 8.75 1946 - 1.36E+06 - - - -1.4186 - 2.739 0.418 - 763.1 1 2 0 -0.0017 11 0 0 0 9.18E+07 7.71E+07 - - - 4.8536 0.9989 221125_WJC_METTL3_EV_vs_WT_F05.08627.08627.3 0.0357 Sep-32 R.KLEEVQQLR.R "sp|Q6P2H3|CEP85_HUMAN,tr|H7BZW2|H7BZW2_HUMAN" 2 1141.6455 3.61 61376 8627 3 1141.644253 381.5558 Centrosomal protein of 85 kDa OS=Homo sapiens OX=9606 GN=CEP85 PE=1 SV=1 6.14 1946.4 - 920449 - - - -1.1116 - 1.964 0.24 - 189 1 2 0 -0.0013 9 0 0 0 1.16E+07 3.22E+06 - - - 3.2497 0.9999 221125_WJC_METTL3_EV_vs_WT_F05.08633.08633.3 0.000122 13/40 R.AAEIYGVTHTR.G sp|Q9HCS7|SYF1_HUMAN 1 1216.62 1.32 61379 8633 3 1216.619345 406.5473 Pre-mRNA-splicing factor SYF1 OS=Homo sapiens OX=9606 GN=XAB2 PE=1 SV=2 6.79 1947.1 - 832583 - - - -0.568 - 2.113 0.426 - 222.8 1 2 0 -0.0007 11 0 0 0 2.84E+07 2.16E+07 - - - 5.4145 0.7896 221125_WJC_METTL3_EV_vs_WT_F05.08634.08634.2 0.00327 20-Oct R.ADQSFTSPPPR[166.11].D "sp|Q9HBM6|TAF9B_HUMAN,sp|Q16594|TAF9_HUMAN,tr|D6RIE8|D6RIE8_HUMAN,tr|D6RIV9|D6RIV9_HUMAN,tr|D6RIY1|D6RIY1_HUMAN,tr|D6RGK3|D6RGK3_HUMAN,tr|D6RHW1|D6RHW1_HUMAN" 7 1211.581 0.66 61380 8634 2 1212.579475 606.7978 Transcription initiation factor TFIID subunit 9B OS=Homo sapiens OX=9606 GN=TAF9B PE=1 SV=1 5.88 1947.3 - 646528 - - - 824.0918 - 1.547 0.382 - 330.2 1 2 0 0.9985 11 0 0 0 5.79E+06 8.82E+06 - - - 2.7293 0.9992 221125_WJC_METTL3_EV_vs_WT_F05.08638.08638.2 0.00419 24-Sep R.VAVPNGQPPSAAR.Y sp|Q9UPQ9|TNR6B_HUMAN 1 1262.6731 2.93 61382 8638 2 1262.671698 632.3438 Trinucleotide repeat-containing gene 6B protein OS=Homo sapiens OX=9606 GN=TNRC6B PE=1 SV=4 9.72 1947.8 - 699815 - - - -1.1373 - 1.725 0.327 - 138.8 1 2 0 -0.0014 13 0 0 0 1.89E+07 6.44E+06 - - - 2.8551 0.9997 221125_WJC_METTL3_EV_vs_WT_F05.08643.08643.2 6.85E-05 14-Nov R.HQVQLLGR.G sp|Q9BUQ8|DDX23_HUMAN 1 949.5457 3.07 61385 8643 2 949.544799 475.7802 Probable ATP-dependent RNA helicase DDX23 OS=Homo sapiens OX=9606 GN=DDX23 PE=1 SV=3 9.76 1948.5 - 2.56E+06 - - - -0.9994 - 2.162 0.331 - 371.6 1 2 0 -0.0009 8 0 0 0 4.65E+07 1.52E+07 - - - 3.8109 0.9998 221125_WJC_METTL3_EV_vs_WT_F05.08645.08645.2 0.000226 13/20 R.NAITSSYSSTR.G "sp|Q96HA1|P121A_HUMAN,sp|A8CG34|P121C_HUMAN,tr|C9JFL1|C9JFL1_HUMAN" 3 1185.5626 1.19 61387 8645 2 1185.561203 593.7886 Nuclear envelope pore membrane protein POM 121 OS=Homo sapiens OX=9606 GN=POM121 PE=1 SV=2 8.75 1948.6 - 4.88E+06 - - - -1.1615 - 2.299 0.442 - 682 1 2 0 -0.0014 11 0 0 0 9.18E+07 7.71E+07 - - - 4.5572 0.9987 221125_WJC_METTL3_EV_vs_WT_F05.08646.08646.2 0.17 14-Sep K.K[136.11]VVQLDVR[166.11].D "sp|O95831|AIFM1_HUMAN,tr|A0A6Q8PFW2|A0A6Q8PFW2_HUMAN,tr|A0A6Q8PFA7|A0A6Q8PFA7_HUMAN,tr|A0A6Q8PHJ9|A0A6Q8PHJ9_HUMAN,tr|A0A6Q8PFS4|A0A6Q8PFS4_HUMAN,tr|A0A7I2PK44|A0A7I2PK44_HUMAN,tr|A0A6Q8PG15|A0A6Q8PG15_HUMAN,tr|A0A6Q8PFE1|A0A6Q8PFE1_HUMAN,tr|A0A7I2RLJ8|A0A7I2RLJ8_HUMAN,tr|A0A6Q8PFQ8|A0A6Q8PFQ8_HUMAN,tr|A0A6Q8PHC0|A0A6Q8PHC0_HUMAN,tr|A0A6Q8PFM5|A0A6Q8PFM5_HUMAN" 12 973.6039 0.49 61388 8646 2 973.601591 487.8092 "Apoptosis-inducing factor 1, mitochondrial OS=Homo sapiens OX=9606 GN=AIFM1 PE=1 SV=1" 8.75 1948.8 - 1.37E+06 - - - -2.4075 - 1.943 0.285 - 376 1 2 0 -0.0023 8 0 0 0 7.92E+06 1.63E+07 - - - 3.1486 0.9962 221125_WJC_METTL3_EV_vs_WT_F05.08650.08650.2 0.00202 18-Nov R.LLEEANKYEK.T "sp|Q15643|TRIPB_HUMAN,tr|H0YJ97|H0YJ97_HUMAN" 2 1235.6398 1.36 61390 8650 2 1235.637711 618.8272 Thyroid receptor-interacting protein 11 OS=Homo sapiens OX=9606 GN=TRIP11 PE=1 SV=3 4.79 1949.3 - 3.71E+06 - - - -1.6647 - 2.111 0.402 - 385 1 2 1 -0.0021 10 0 0 0 6.89E+07 5.06E+07 - - - 4.0951 0.9889 221125_WJC_METTL3_EV_vs_WT_F05.08651.08651.2 2.86E-05 13/16 P.PMEK[136.11]PEVVK[136.11].T "sp|P62841|RS15_HUMAN,tr|K7EJ78|K7EJ78_HUMAN,tr|K7EM56|K7EM56_HUMAN,tr|A0A0B4J2B4|A0A0B4J2B4_HUMAN,tr|S4R456|S4R456_HUMAN,tr|K7ELC2|K7ELC2_HUMAN,tr|K7EQJ5|K7EQJ5_HUMAN,tr|S4R417|S4R417_HUMAN" 8 1071.5969 1.38 61391 8651 2 1071.598793 536.8057 40S ribosomal protein S15 OS=Homo sapiens OX=9606 GN=RPS15 PE=1 SV=2 6.56 1949.4 - 491467 - - - 1.7507 - 2.466 0.502 - 892.9 1 1 0 0.0019 9 0 0 0 3.55E+07 2.58E+07 - - - 5.3594 0.9998 221125_WJC_METTL3_EV_vs_WT_F05.08652.08652.2 6.20E-05 13/18 R.HYGGLTGLNK[136.11].A "sp|Q8N0Y7|PGAM4_HUMAN,sp|P15259|PGAM2_HUMAN,sp|P18669|PGAM1_HUMAN" 3 1066.5651 1.46 61392 8652 2 1066.564196 534.2898 Probable phosphoglycerate mutase 4 OS=Homo sapiens OX=9606 GN=PGAM4 PE=3 SV=1 8.6 1949.5 - 1.18E+06 - - - -0.841 - 2.125 0.473 - 416.9 1 2 0 -0.0009 10 0 0 0 4.95E+07 3.39E+07 - - - 4.6383 0.9991 221125_WJC_METTL3_EV_vs_WT_F05.08655.08655.2 0.27 14-Aug K.KVVQLDVR.D "sp|O95831|AIFM1_HUMAN,tr|A0A6Q8PFW2|A0A6Q8PFW2_HUMAN,tr|A0A6Q8PFA7|A0A6Q8PFA7_HUMAN,tr|A0A6Q8PHJ9|A0A6Q8PHJ9_HUMAN,tr|A0A6Q8PFS4|A0A6Q8PFS4_HUMAN,tr|A0A7I2PK44|A0A7I2PK44_HUMAN,tr|A0A6Q8PG15|A0A6Q8PG15_HUMAN,tr|A0A6Q8PFE1|A0A6Q8PFE1_HUMAN,tr|A0A7I2RLJ8|A0A7I2RLJ8_HUMAN,tr|A0A6Q8PFQ8|A0A6Q8PFQ8_HUMAN,tr|A0A6Q8PHC0|A0A6Q8PHC0_HUMAN,tr|A0A6Q8PFM5|A0A6Q8PFM5_HUMAN" 12 955.5815 0.49 61395 8655 2 955.580074 478.798 "Apoptosis-inducing factor 1, mitochondrial OS=Homo sapiens OX=9606 GN=AIFM1 PE=1 SV=1" 8.75 1949.9 - 544986 - - - -1.4557 - 1.798 0.277 - 320.7 1 2 0 -0.0014 8 0 0 0 7.92E+06 1.63E+07 - - - 2.8559 0.9965 221125_WJC_METTL3_EV_vs_WT_F05.08658.08658.3 1.97E-05 17/36 A.PPMEKPEVVK.T "sp|P62841|RS15_HUMAN,tr|K7EJ78|K7EJ78_HUMAN,tr|K7EM56|K7EM56_HUMAN,tr|A0A0B4J2B4|A0A0B4J2B4_HUMAN,tr|S4R456|S4R456_HUMAN,tr|K7ELC2|K7ELC2_HUMAN,tr|K7EQJ5|K7EQJ5_HUMAN,tr|S4R417|S4R417_HUMAN" 8 1152.6213 1.85 61396 8658 3 1152.619507 385.2144 40S ribosomal protein S15 OS=Homo sapiens OX=9606 GN=RPS15 PE=1 SV=2 6.56 1950.4 - 1.02E+06 - - - -1.5391 - 2.602 0.486 - 477.7 1 1 0 -0.0018 10 0 0 0 5.42E+07 2.93E+07 - - - 6.7507 0.9653 221125_WJC_METTL3_EV_vs_WT_F05.08660.08660.2 0.0303 13/18 A.PPMEKPEVVK.T "sp|P62841|RS15_HUMAN,tr|K7EJ78|K7EJ78_HUMAN,tr|K7EM56|K7EM56_HUMAN,tr|A0A0B4J2B4|A0A0B4J2B4_HUMAN,tr|S4R456|S4R456_HUMAN,tr|K7ELC2|K7ELC2_HUMAN,tr|K7EQJ5|K7EQJ5_HUMAN,tr|S4R417|S4R417_HUMAN" 8 1152.6213 1.37 61398 8660 2 1152.618144 577.3179 40S ribosomal protein S15 OS=Homo sapiens OX=9606 GN=RPS15 PE=1 SV=2 6.56 1950.6 - 1.30E+06 - - - -2.7216 - 2.536 0.369 - 695.9 1 1 0 -0.0031 10 0 0 0 4.73E+07 3.46E+07 - - - 4.363 0.9997 221125_WJC_METTL3_EV_vs_WT_F05.08661.08661.3 0.00124 Nov-40 R.LLQHFQDGGER.A sp|Q5BKU9|OXLD1_HUMAN 1 1298.6367 1.28 61399 8661 3 1298.634354 433.8862 Oxidoreductase-like domain-containing protein 1 OS=Homo sapiens OX=9606 GN=OXLD1 PE=2 SV=1 5.32 1950.8 - 907084 - - - -1.8435 - 1.925 0.375 - 231.8 1 2 0 -0.0024 11 0 0 0 1.60E+07 1.25E+07 - - - 4.5807 0.9998 221125_WJC_METTL3_EV_vs_WT_F05.08667.08667.2 1.83E-06 13/18 R.HYGGLTGLNK.A "sp|Q8N0Y7|PGAM4_HUMAN,sp|P15259|PGAM2_HUMAN,sp|P18669|PGAM1_HUMAN" 3 1058.5509 1.47 61403 8667 2 1058.552653 530.2827 Probable phosphoglycerate mutase 4 OS=Homo sapiens OX=9606 GN=PGAM4 PE=3 SV=1 8.6 1951.5 - 1.79E+06 - - - 1.6627 - 2.296 0.534 - 429.9 1 2 0 0.0018 10 0 0 0 4.97E+07 3.39E+07 - - - 5.3046 0.9923 221125_WJC_METTL3_EV_vs_WT_F05.08668.08668.3 0.0826 Sep-32 K.QK[136.11]PC[160.03]DLPLR[166.11].L sp|O00425|IF2B3_HUMAN 1 1143.6189 0.001 61404 8668 3 1143.616051 382.2136 Insulin-like growth factor 2 mRNA-binding protein 3 OS=Homo sapiens OX=9606 GN=IGF2BP3 PE=1 SV=2 8.22 1951.6 - 816114 - - - -2.5209 - 1.874 0.192 - 121 1 2 0 -0.0029 9 0 0 0 0.00E+00 5.18E+07 - - - 2.5727 0.9946 221125_WJC_METTL3_EV_vs_WT_F05.08670.08670.3 0.0201 Sep-40 R.LLQHFQDGGER[166.11].A sp|Q5BKU9|OXLD1_HUMAN 1 1308.645 1.28 61406 8670 3 1308.64372 437.2223 Oxidoreductase-like domain-containing protein 1 OS=Homo sapiens OX=9606 GN=OXLD1 PE=2 SV=1 5.32 1951.9 - 536598 - - - -0.9919 - 1.561 0.214 - 119 1 2 0 -0.0013 11 0 0 0 1.60E+07 1.25E+07 - - - 2.1906 0.9997 221125_WJC_METTL3_EV_vs_WT_F05.08671.08671.2 0.00023 22-Dec R.DGEEAGAYDGPR[166.11].T "sp|P30101|PDIA3_HUMAN,tr|H7BZJ3|H7BZJ3_HUMAN" 2 1245.5137 0.8 61407 8671 2 1245.510689 623.7641 Protein disulfide-isomerase A3 OS=Homo sapiens OX=9606 GN=PDIA3 PE=1 SV=4 3.92 1952 - 501341 - - - -2.4408 - 2.412 0.577 - 585.4 1 2 0 -0.003 12 0 0 0 2.01E+07 2.51E+07 - - - 5.6184 1 221125_WJC_METTL3_EV_vs_WT_F05.08674.08674.3 3.66E-06 15/40 K.TPESKPTILVK.N sp|Q9Y3B9|RRP15_HUMAN 1 1211.7125 1.07 61408 8674 3 1211.711147 404.9115 RRP15-like protein OS=Homo sapiens OX=9606 GN=RRP15 PE=1 SV=2 8.26 1952.4 - 1.71E+06 - - - -1.1488 - 2.678 0.448 - 293.9 1 2 0 -0.0014 11 0 0 0 4.17E+07 3.90E+07 - - - 6.3328 0.9999 221125_WJC_METTL3_EV_vs_WT_F05.08675.08675.3 6.25E-06 13/40 R.FAC[160.03]HSASLTVR[166.11].N "sp|Q15233|NONO_HUMAN,tr|A0A7I2V535|A0A7I2V535_HUMAN,tr|A0A7I2V4N2|A0A7I2V4N2_HUMAN,tr|A0A7I2V4K9|A0A7I2V4K9_HUMAN,tr|A0A7I2V464|A0A7I2V464_HUMAN,tr|A0A7P0MRW0|A0A7P0MRW0_HUMAN,tr|C9IZL7|C9IZL7_HUMAN,tr|A0A7I2V4J2|A0A7I2V4J2_HUMAN,tr|A0A7I2V5Y7|A0A7I2V5Y7_HUMAN,tr|C9JYS8|C9JYS8_HUMAN" 10 1257.6164 0.71 61409 8675 3 1257.613369 420.2127 Non-POU domain-containing octamer-binding protein OS=Homo sapiens OX=9606 GN=NONO PE=1 SV=4 8.26 1952.5 - 1.84E+06 - - - -2.3791 - 2.25 0.507 - 174.8 1 2 0 -0.003 11 0 0 0 2.07E+08 2.93E+08 - - - 6.4954 0.9996 221125_WJC_METTL3_EV_vs_WT_F05.08676.08676.3 0.00817 13/40 K.TPESK[136.11]PTILVK[136.11].N sp|Q9Y3B9|RRP15_HUMAN 1 1227.7409 1.07 61410 8676 3 1227.739067 410.2543 RRP15-like protein OS=Homo sapiens OX=9606 GN=RRP15 PE=1 SV=2 8.26 1952.5 - 1.77E+06 - - - -1.5248 - 1.853 0.351 - 215.2 1 2 0 -0.0019 11 0 0 0 4.17E+07 3.90E+07 - - - 4.205 0.9948 221125_WJC_METTL3_EV_vs_WT_F05.08677.08677.3 9.33E-05 18/36 A.PPMEK[136.11]PEVVK[136.11].T "sp|P62841|RS15_HUMAN,tr|K7EJ78|K7EJ78_HUMAN,tr|K7EM56|K7EM56_HUMAN,tr|A0A0B4J2B4|A0A0B4J2B4_HUMAN,tr|S4R456|S4R456_HUMAN,tr|K7ELC2|K7ELC2_HUMAN,tr|K7EQJ5|K7EQJ5_HUMAN,tr|S4R417|S4R417_HUMAN" 8 1168.6497 2.52 61411 8677 3 1168.648449 390.5572 40S ribosomal protein S15 OS=Homo sapiens OX=9606 GN=RPS15 PE=1 SV=2 6.56 1952.7 - 725516 - - - -1.0542 - 2.718 0.402 - 470.9 1 1 0 -0.0012 10 0 0 0 8.70E+07 3.45E+07 - - - 5.9417 0.9995 221125_WJC_METTL3_EV_vs_WT_F05.08680.08680.2 0.00111 12-Jul R.DNQWNPR.Q "sp|Q9Y520|PRC2C_HUMAN,tr|E7EPN9|E7EPN9_HUMAN" 2 928.4151 1.14 61412 8680 2 928.415015 465.2148 Protein PRRC2C OS=Homo sapiens OX=9606 GN=PRRC2C PE=1 SV=4 5.84 1953.1 - 2.46E+06 - - - -0.1217 - 1.566 0.348 - 360 1 2 0 -0.0001 7 0 0 0 8.20E+07 7.20E+07 - - - 3.0325 0.9998 221125_WJC_METTL3_EV_vs_WT_F05.08688.08688.2 0.00338 16-Oct R.EAQTLQQYR[166.11].V "sp|P51692|STA5B_HUMAN,sp|P42229|STA5A_HUMAN,tr|A0A7I2YQY3|A0A7I2YQY3_HUMAN,tr|K7EIF9|K7EIF9_HUMAN,tr|K7EK35|K7EK35_HUMAN,tr|A0A7I2V380|A0A7I2V380_HUMAN,tr|A0A7I2YQF1|A0A7I2YQF1_HUMAN" 7 1145.5705 0.21 61418 8688 2 1145.570514 573.7925 Signal transducer and activator of transcription 5B OS=Homo sapiens OX=9606 GN=STAT5B PE=1 SV=2 6.1 1954.1 - 692326 - - - 0.0506 - 2.181 0.354 - 580.4 1 2 0 0.0001 9 0 0 0 4.39E+06 2.07E+07 - - - 3.9116 1 221125_WJC_METTL3_EV_vs_WT_F05.08689.08689.3 4.90E-07 13/40 R.FAC[160.03]HSASLTVR.N "sp|Q15233|NONO_HUMAN,tr|A0A7I2V535|A0A7I2V535_HUMAN,tr|A0A7I2V4N2|A0A7I2V4N2_HUMAN,tr|A0A7I2V4K9|A0A7I2V4K9_HUMAN,tr|A0A7I2V464|A0A7I2V464_HUMAN,tr|A0A7P0MRW0|A0A7P0MRW0_HUMAN,tr|C9IZL7|C9IZL7_HUMAN,tr|A0A7I2V4J2|A0A7I2V4J2_HUMAN,tr|A0A7I2V5Y7|A0A7I2V5Y7_HUMAN,tr|C9JYS8|C9JYS8_HUMAN" 10 1247.6081 0.71 61419 8689 3 1247.606737 416.8766 Non-POU domain-containing octamer-binding protein OS=Homo sapiens OX=9606 GN=NONO PE=1 SV=4 8.26 1954.1 - 2.31E+06 - - - -1.0853 - 2.594 0.574 - 157.7 1 2 0 -0.0014 11 0 0 0 2.07E+08 2.93E+08 - - - 7.647 0.993 221125_WJC_METTL3_EV_vs_WT_F05.08691.08691.3 0.262 Oct-40 K.AQLGLGHSYSR[166.11].A "sp|O00567|NOP56_HUMAN,tr|A0A494C128|A0A494C128_HUMAN,tr|Q5JXT2|Q5JXT2_HUMAN" 3 1197.613 1.76 61421 8691 3 1197.609739 400.2116 Nucleolar protein 56 OS=Homo sapiens OX=9606 GN=NOP56 PE=1 SV=4 8.8 1954.4 - 280649 - - - -2.7146 - 2.06 0.192 - 125.9 1 2 0 -0.0033 11 0 0 0 1.33E+07 7.58E+06 - - - 2.7328 0.9623 221125_WJC_METTL3_EV_vs_WT_F05.08692.08692.3 0.00228 13/40 P.PPHMGELDQER.L "sp|Q6Y7W6|GGYF2_HUMAN,tr|A0A7I2V3H7|A0A7I2V3H7_HUMAN,tr|I1E4Y6|I1E4Y6_HUMAN,tr|A0A7I2V516|A0A7I2V516_HUMAN,tr|A0A7I2V3H0|A0A7I2V3H0_HUMAN,tr|C9JHW1|C9JHW1_HUMAN,tr|A0A7I2V361|A0A7I2V361_HUMAN,tr|E7ESB6|E7ESB6_HUMAN" 8 1307.5928 2.95 61422 8692 3 1307.594738 436.8716 GRB10-interacting GYF protein 2 OS=Homo sapiens OX=9606 GN=GIGYF2 PE=1 SV=1 4.65 1954.5 - 196560 - - - 1.4553 - 2.362 0.3 - 274 1 1 0 0.0019 11 0 0 0 5.48E+06 1.86E+06 - - - 4.3259 0.9998 221125_WJC_METTL3_EV_vs_WT_F05.08696.08696.2 0.000421 18-Oct R.ATAFNEQVDK[136.11].F sp|P27694|RFA1_HUMAN 1 1129.5495 1.15 61424 8696 2 1129.549496 565.782 Replication protein A 70 kDa DNA-binding subunit OS=Homo sapiens OX=9606 GN=RPA1 PE=1 SV=2 4.37 1955 - 1.96E+06 - - - -0.0062 - 2.067 0.437 - 470.5 1 2 0 0 10 0 0 0 8.68E+07 7.55E+07 - - - 4.2954 0.9999 221125_WJC_METTL3_EV_vs_WT_F05.08698.08698.2 6.62E-07 20-Dec R.FAC[160.03]HSASLTVR[166.11].N "sp|Q15233|NONO_HUMAN,tr|A0A7I2V535|A0A7I2V535_HUMAN,tr|A0A7I2V4N2|A0A7I2V4N2_HUMAN,tr|A0A7I2V4K9|A0A7I2V4K9_HUMAN,tr|A0A7I2V464|A0A7I2V464_HUMAN,tr|A0A7P0MRW0|A0A7P0MRW0_HUMAN,tr|C9IZL7|C9IZL7_HUMAN,tr|A0A7I2V4J2|A0A7I2V4J2_HUMAN,tr|A0A7I2V5Y7|A0A7I2V5Y7_HUMAN,tr|C9JYS8|C9JYS8_HUMAN" 10 1257.6164 1.01 61426 8698 2 1257.616565 629.8155 Non-POU domain-containing octamer-binding protein OS=Homo sapiens OX=9606 GN=NONO PE=1 SV=4 8.26 1955.2 - 613367 - - - 0.1622 - 2.273 0.548 - 556.3 1 2 0 0.0002 11 0 0 0 2.51E+07 2.49E+07 - - - 5.3097 0.9415 221125_WJC_METTL3_EV_vs_WT_F05.08699.08699.3 0.296 Jul-44 K.ISSDLDGHPVPK[136.11].Q "sp|P29401|TKT_HUMAN,tr|E9PFF2|E9PFF2_HUMAN,tr|F8W888|F8W888_HUMAN" 3 1271.6601 0.68 61427 8699 3 1271.662072 424.894 Transketolase OS=Homo sapiens OX=9606 GN=TKT PE=1 SV=3 5.21 1955.3 - 394307 - - - 1.5381 - 1.329 0.173 - 39.7 4 2 0 0.002 12 0 0 0 5.73E+06 8.48E+06 - - - 0.978 0.9991 221125_WJC_METTL3_EV_vs_WT_F05.08704.08704.2 0.00415 14-Jul K.GANPVEIR.R "sp|P10809|CH60_HUMAN,tr|A0A7I2V2X6|A0A7I2V2X6_HUMAN,tr|A0A7I2YQK6|A0A7I2YQK6_HUMAN,tr|A0A7I2V599|A0A7I2V599_HUMAN,tr|E7EXB4|E7EXB4_HUMAN,tr|A0A7I2YQ71|A0A7I2YQ71_HUMAN,tr|E7ESH4|E7ESH4_HUMAN,tr|A0A7I2V5M1|A0A7I2V5M1_HUMAN,tr|A0A7I2V5K3|A0A7I2V5K3_HUMAN,tr|A0A7I2V369|A0A7I2V369_HUMAN" 10 854.461 1.09 61430 8704 2 854.460044 428.2378 "60 kDa heat shock protein, mitochondrial OS=Homo sapiens OX=9606 GN=HSPD1 PE=1 SV=2" 6 1956 - 776982 - - - -1.1376 - 1.541 0.321 - 259.5 1 2 0 -0.001 8 0 0 0 1.01E+08 9.23E+07 - - - 2.7158 0.9999 221125_WJC_METTL3_EV_vs_WT_F05.08705.08705.2 9.30E-06 14/22 K.VSGAQEMVSSAK[136.11].D "sp|O60664|PLIN3_HUMAN,tr|K7ERZ3|K7ERZ3_HUMAN,tr|K7EL96|K7EL96_HUMAN,tr|K7ER39|K7ER39_HUMAN" 4 1200.59 0.66 61431 8705 2 1200.589121 601.3023 Perilipin-3 OS=Homo sapiens OX=9606 GN=PLIN3 PE=1 SV=3 5.97 1956.2 - 405707 - - - -0.7221 - 2.584 0.495 - 869 1 2 0 -0.0009 12 0 0 0 6.67E+06 1.01E+07 - - - 5.1947 0.9998 221125_WJC_METTL3_EV_vs_WT_F05.08706.08706.2 0.000142 22-Sep R.DGEEAGAYDGPR.T "sp|P30101|PDIA3_HUMAN,tr|H7BZJ3|H7BZJ3_HUMAN" 2 1235.5055 0.8 61432 8706 2 1235.50554 618.76 Protein disulfide-isomerase A3 OS=Homo sapiens OX=9606 GN=PDIA3 PE=1 SV=4 3.92 1956.3 - 372821 - - - 0.0656 - 1.919 0.497 - 301.4 1 2 0 0.0001 12 0 0 0 2.01E+07 2.51E+07 - - - 4.4268 0.9955 221125_WJC_METTL3_EV_vs_WT_F05.08707.08707.2 1.54 16-Sep R.RGMTVEGLK.Q "sp|P07814|SYEP_HUMAN,tr|V9GYZ6|V9GYZ6_HUMAN" 2 989.5328 1.09 61433 8707 2 989.534099 495.7737 Bifunctional glutamate\proline--tRNA ligase OS=Homo sapiens OX=9606 GN=EPRS1 PE=1 SV=5 8.75 1956.4 - 316508 - - - 1.3117 - 1.658 0.135 - 262.3 1 2 0 0.0013 9 0 0 0 8.84E+06 8.09E+06 - - - 1.5005 0.9997 221125_WJC_METTL3_EV_vs_WT_F05.08708.08708.2 0.00481 13/26 K.LAAVAQDEEENASR.S sp|Q99666|RGPD5_HUMAN 1 1501.7009 1.68 61434 8708 2 1501.703881 751.8577 RANBP2-like and GRIP domain-containing protein 5\6 OS=Homo sapiens OX=9606 GN=RGPD5 PE=1 SV=3 4 1956.5 - 130038 - - - 2.0084 - 2.519 0.499 - 493.3 1 2 0 0.003 14 0 0 0 3.64E+06 2.16E+06 - - - 5.0441 0.9997 221125_WJC_METTL3_EV_vs_WT_F05.08717.08717.2 0.0027 14-Aug K.GANPVEIR[166.11].R "sp|P10809|CH60_HUMAN,tr|A0A7I2V2X6|A0A7I2V2X6_HUMAN,tr|A0A7I2YQK6|A0A7I2YQK6_HUMAN,tr|A0A7I2V599|A0A7I2V599_HUMAN,tr|E7EXB4|E7EXB4_HUMAN,tr|A0A7I2YQ71|A0A7I2YQ71_HUMAN,tr|E7ESH4|E7ESH4_HUMAN,tr|A0A7I2V5M1|A0A7I2V5M1_HUMAN,tr|A0A7I2V5K3|A0A7I2V5K3_HUMAN,tr|A0A7I2V369|A0A7I2V369_HUMAN" 10 864.4693 1.1 61439 8717 2 864.469342 433.2419 "60 kDa heat shock protein, mitochondrial OS=Homo sapiens OX=9606 GN=HSPD1 PE=1 SV=2" 6 1957.7 - 1.59E+06 - - - 0.0648 - 1.755 0.364 - 353.2 1 2 0 0.0001 8 0 0 0 1.01E+08 9.12E+07 - - - 3.4259 0.8191 221125_WJC_METTL3_EV_vs_WT_F05.08718.08718.2 0.000854 16-Aug R.GIEQAVQSH.A "sp|Q16891|MIC60_HUMAN,tr|B9A067|B9A067_HUMAN,tr|C9J406|C9J406_HUMAN,tr|H7C463|H7C463_HUMAN" 4 967.4723 - 61440 8718 2 967.469085 484.7434 MICOS complex subunit MIC60 OS=Homo sapiens OX=9606 GN=IMMT PE=1 SV=1 5.24 1957.7 - 1.21E+06 - - - -3.3324 - 1.662 0.307 - 209.7 1 1 0 -0.0032 9 0 0 0 - - - - - 2.7772 0.9774 221125_WJC_METTL3_EV_vs_WT_F05.08719.08719.3 0.211 Dec-40 K.QLVAEAIHSGK[136.11].K "sp|Q9BWU0|NADAP_HUMAN,tr|A0A087X0M4|A0A087X0M4_HUMAN,tr|A0A087WWF4|A0A087WWF4_HUMAN" 3 1159.6441 0.8 61441 8719 3 1159.643267 387.5553 Kanadaptin OS=Homo sapiens OX=9606 GN=SLC4A1AP PE=1 SV=1 6.75 1957.8 - 699437 - - - -0.6942 - 1.876 0.089 - 99.5 1 2 0 -0.0008 11 0 0 0 1.80E+07 2.26E+07 - - - 1.3193 0.9998 221125_WJC_METTL3_EV_vs_WT_F05.08720.08720.2 9.46E-06 26-Nov R.GNLGAGNGNLQGPR.H "sp|P43243|MATR3_HUMAN,tr|D6RE02|D6RE02_HUMAN,tr|B3KM87|B3KM87_HUMAN,tr|A8MXP9|A8MXP9_HUMAN,tr|D6RAY2|D6RAY2_HUMAN,tr|D6R991|D6R991_HUMAN,tr|A0A0R4J2E8|A0A0R4J2E8_HUMAN,tr|D6RAM9|D6RAM9_HUMAN,tr|D6RIA2|D6RIA2_HUMAN,tr|H0Y8T4|H0Y8T4_HUMAN,tr|D6REM6|D6REM6_HUMAN,tr|D6RBI2|D6RBI2_HUMAN" 12 1323.6644 1.62 61442 8720 2 1323.666565 662.8395 Matrin-3 OS=Homo sapiens OX=9606 GN=MATR3 PE=1 SV=2 9.75 1958 - 440204 - - - 1.6658 - 2.393 0.485 - 383.7 1 2 0 0.0022 14 0 0 0 7.00E+07 4.31E+07 - - - 4.8121 0.9933 221125_WJC_METTL3_EV_vs_WT_F05.08722.08722.2 0.0166 20-Aug R.LFSQGQDVSNK[136.11].V "sp|P55196|AFAD_HUMAN,tr|H0Y8L4|H0Y8L4_HUMAN,tr|J3KN01|J3KN01_HUMAN,tr|H0Y948|H0Y948_HUMAN,tr|H0Y8U8|H0Y8U8_HUMAN,tr|A0A804HJ20|A0A804HJ20_HUMAN,tr|A8MQ02|A8MQ02_HUMAN" 7 1229.6132 0.78 61444 8722 2 1229.617197 615.8139 Afadin OS=Homo sapiens OX=9606 GN=AFDN PE=1 SV=3 5.84 1958.2 - 273822 - - - 3.2783 - 1.292 0.335 - 71.2 1 2 0 0.004 11 0 0 0 5.68E+06 7.28E+06 - - - 2.2071 0.7743 221125_WJC_METTL3_EV_vs_WT_F05.08728.08728.2 0.18 20-Aug D.K[136.11]GLPHGNVSAR.K sp|P52333|JAK3_HUMAN 1 1142.64 - 61448 8728 2 1142.641414 572.3273 Tyrosine-protein kinase JAK3 OS=Homo sapiens OX=9606 GN=JAK3 PE=1 SV=2 11 1959 - 1.16E+06 - - - 1.2462 - 1.715 0.143 - 71.6 2 1 0 0.0014 11 0 0 0 - - - - - 1.4215 0.9991 221125_WJC_METTL3_EV_vs_WT_F05.08730.08730.2 0.00184 18-Sep R.GEEVTLSNPK.G "sp|Q14669|TRIPC_HUMAN,tr|A0A6Q8PHK0|A0A6Q8PHK0_HUMAN,tr|A0A6Q8PGG9|A0A6Q8PGG9_HUMAN" 3 1072.5401 1.2 61450 8730 2 1072.541776 537.2773 E3 ubiquitin-protein ligase TRIP12 OS=Homo sapiens OX=9606 GN=TRIP12 PE=1 SV=1 4.53 1959.3 - 318365 - - - 1.6055 - 1.671 0.34 - 344.9 1 2 0 0.0017 10 0 0 0 9.35E+06 7.82E+06 - - - 2.9848 0.8763 221125_WJC_METTL3_EV_vs_WT_F05.08732.08732.3 0.258 Aug-36 R.LRDTEEMLSK.K sp|Q9H444|CHM4B_HUMAN 1 1220.6071 0.75 61452 8732 3 1220.605312 407.8763 Charged multivesicular body protein 4b OS=Homo sapiens OX=9606 GN=CHMP4B PE=1 SV=1 4.68 1959.5 - 289002 - - - -1.455 - 1.383 0.162 - 74 1 2 1 -0.0018 10 0 0 0 7.90E+06 1.06E+07 - - - 1.2926 0.9979 221125_WJC_METTL3_EV_vs_WT_F05.08735.08735.3 0.0174 Dec-36 R.LEQEIATYRR.L "sp|Q04695|K1C17_HUMAN,sp|P02533|K1C14_HUMAN,sp|P35900|K1C20_HUMAN,sp|P08779|K1C16_HUMAN,tr|A0A3B3IS58|A0A3B3IS58_HUMAN,tr|F5GWP8|F5GWP8_HUMAN" 6 1277.6728 2681.13 61453 8735 3 1277.673029 426.8982 "Keratin, type I cytoskeletal 17 OS=Homo sapiens OX=9606 GN=KRT17 PE=1 SV=2" 6.14 1959.9 - 3.72E+06 - - - 0.1792 - 2.152 0.182 - 262.1 1 2 0 0.0002 10 0 0 0 1.45E+08 5.42E+04 - - - 2.8073 0.9975 221125_WJC_METTL3_EV_vs_WT_F05.08738.08738.3 0.0019 Sep-36 K.LR[166.11]ETLEEYNK[136.11].E "sp|Q13948|CASP_HUMAN,sp|P39880|CUX1_HUMAN,tr|A0A2R8Y852|A0A2R8Y852_HUMAN,tr|A0A2R8YDI1|A0A2R8YDI1_HUMAN" 4 1311.679 0.88 61456 8738 3 1311.681295 438.2336 Protein CASP OS=Homo sapiens OX=9606 GN=CUX1 PE=1 SV=2 4.79 1960.3 - 448096 - - - 1.787 - 1.925 0.333 - 145.1 1 2 1 0.0023 10 0 0 0 1.52E+07 1.71E+07 - - - 4.1646 0.8815 221125_WJC_METTL3_EV_vs_WT_F05.08739.08739.2 4.99 18-May R.LEQEIATYRR.L "sp|Q04695|K1C17_HUMAN,sp|P02533|K1C14_HUMAN,sp|P35900|K1C20_HUMAN,sp|P08779|K1C16_HUMAN,tr|A0A3B3IS58|A0A3B3IS58_HUMAN,tr|F5GWP8|F5GWP8_HUMAN" 6 1277.6728 999 61457 8739 2 1277.671265 639.8437 "Keratin, type I cytoskeletal 17 OS=Homo sapiens OX=9606 GN=KRT17 PE=1 SV=2" 6.14 1960.4 - 230968 - - - -1.2014 - 1.02 0.008 - 44.5 1 2 0 -0.0015 10 0 0 0 1.06E+07 0.00E+00 - - - -0.8451 0.9988 221125_WJC_METTL3_EV_vs_WT_F05.08743.08743.3 0.0498 Oct-40 R.MGHSAPLTNIR[166.11].Y "sp|Q8NI36|WDR36_HUMAN,tr|A0A0A0MTB8|A0A0A0MTB8_HUMAN" 2 1205.6214 1.01 61459 8743 3 1205.621777 402.8811 WD repeat-containing protein 36 OS=Homo sapiens OX=9606 GN=WDR36 PE=1 SV=1 9.52 1961 - 522247 - - - 0.2745 - 1.675 0.286 - 118 1 2 0 0.0003 11 0 0 0 2.09E+07 2.06E+07 - - - 3.1939 0.9996 221125_WJC_METTL3_EV_vs_WT_F05.08752.08752.2 0.00169 18-Oct K.EK[136.11]PTTALLDK[136.11].V "sp|Q12906|ILF3_HUMAN,tr|K7ER69|K7ER69_HUMAN,tr|K7EKY0|K7EKY0_HUMAN,tr|K7EKJ9|K7EKJ9_HUMAN" 4 1130.6518 1.02 61466 8752 2 1130.652704 566.3332 Interleukin enhancer-binding factor 3 OS=Homo sapiens OX=9606 GN=ILF3 PE=1 SV=3 6.17 1962 - 1.54E+06 - - - 0.8084 - 1.765 0.386 - 197.6 1 2 0 0.0009 10 0 0 0 3.29E+07 3.23E+07 - - - 3.4776 0.9999 221125_WJC_METTL3_EV_vs_WT_F05.08753.08753.2 0.000292 14/26 R.GNLGAGNGNLQGPR[166.11].H "sp|P43243|MATR3_HUMAN,tr|D6RE02|D6RE02_HUMAN,tr|B3KM87|B3KM87_HUMAN,tr|A8MXP9|A8MXP9_HUMAN,tr|D6RAY2|D6RAY2_HUMAN,tr|D6R991|D6R991_HUMAN,tr|A0A0R4J2E8|A0A0R4J2E8_HUMAN,tr|D6RAM9|D6RAM9_HUMAN,tr|D6RIA2|D6RIA2_HUMAN,tr|H0Y8T4|H0Y8T4_HUMAN,tr|D6REM6|D6REM6_HUMAN,tr|D6RBI2|D6RBI2_HUMAN" 12 1333.6726 1.69 61467 8753 2 1333.673323 667.8436 Matrin-3 OS=Homo sapiens OX=9606 GN=MATR3 PE=1 SV=2 9.75 1962.1 - 1.43E+06 - - - 0.5196 - 2.769 0.541 - 655.4 1 2 0 0.0007 14 0 0 0 7.30E+07 4.31E+07 - - - 5.5924 0.9606 221125_WJC_METTL3_EV_vs_WT_F05.08765.08765.2 0.441 16-Jun R.NELQQTINK.L sp|O14777|NDC80_HUMAN 1 1086.5669 2.71 61475 8765 2 1086.56939 544.2907 Kinetochore protein NDC80 homolog OS=Homo sapiens OX=9606 GN=NDC80 PE=1 SV=1 6 1963.6 - 275456 - - - 2.2576 - 1.192 0.175 - 27.6 12 2 0 0.0025 9 0 0 0 9.31E+06 3.44E+06 - - - 0.3588 0.9998 221125_WJC_METTL3_EV_vs_WT_F05.08766.08766.3 0.000293 13/40 K.LRQENMELAER.L sp|P40222|TXLNA_HUMAN 1 1387.6878 1.03 61476 8766 3 1387.689585 463.5699 Alpha-taxilin OS=Homo sapiens OX=9606 GN=TXLNA PE=1 SV=3 4.79 1963.6 - 1.31E+06 - - - 1.2878 - 2.53 0.443 - 401.4 1 2 1 0.0018 11 0 0 0 1.75E+07 1.70E+07 - - - 6.1154 0.9999 221125_WJC_METTL3_EV_vs_WT_F05.08773.08773.2 0.0164 13/24 K.VSVAVEASADSSK[136.11].T "sp|Q99590|SCAFB_HUMAN,tr|F8VXG7|F8VXG7_HUMAN,tr|A0A087WTB7|A0A087WTB7_HUMAN" 3 1256.634 2.24 61481 8773 2 1256.633674 629.3243 Protein SCAF11 OS=Homo sapiens OX=9606 GN=SCAF11 PE=1 SV=2 4.37 1964.4 - 627062 - - - -0.2284 - 2.463 0.43 - 657 1 2 0 -0.0003 13 0 0 0 2.73E+07 1.22E+07 - - - 4.5303 0.9999 221125_WJC_METTL3_EV_vs_WT_F05.08774.08774.2 0.000155 22-Nov R.SLQEQADAAEER.A "tr|F5H7S3|F5H7S3_HUMAN,tr|H0YKJ4|H0YKJ4_HUMAN,tr|H0YK48|H0YK48_HUMAN,tr|H0YN06|H0YN06_HUMAN,tr|B7Z596|B7Z596_HUMAN,tr|A0A494BZZ2|A0A494BZZ2_HUMAN,tr|H7BYY1|H7BYY1_HUMAN" 7 1345.611 1.16 61482 8774 2 1345.610958 673.8128 Tropomyosin alpha-1 chain OS=Homo sapiens OX=9606 GN=TPM1 PE=1 SV=2 4 1964.6 - 524616 - - - -0.0216 - 2.307 0.555 - 399.1 1 2 0 0 12 0 0 0 8.63E+06 7.41E+06 - - - 5.3397 0.9975 221125_WJC_METTL3_EV_vs_WT_F05.08775.08775.3 0.00245 Dec-36 K.LRAELDEVNK.S sp|Q03252|LMNB2_HUMAN 1 1185.6354 1.04 61483 8775 3 1185.631262 396.2191 Lamin-B2 OS=Homo sapiens OX=9606 GN=LMNB2 PE=1 SV=4 4.68 1964.7 - 449047 - - - -3.4488 - 2.354 0.367 - 230.1 1 2 1 -0.0041 10 0 0 0 2.32E+07 2.22E+07 - - - 5.1308 0.9674 221125_WJC_METTL3_EV_vs_WT_F05.08776.08776.2 1.17 14-Sep R.KEQKMLEK.L "sp|Q6UWE0|LRSM1_HUMAN,tr|A0A6Q8PFW1|A0A6Q8PFW1_HUMAN,tr|A0A6Q8PGF7|A0A6Q8PGF7_HUMAN,tr|A0A6Q8PFL5|A0A6Q8PFL5_HUMAN,tr|A0A6Q8PHH6|A0A6Q8PHH6_HUMAN,tr|A0A6Q8PH70|A0A6Q8PH70_HUMAN,tr|A0A6Q8PGB2|A0A6Q8PGB2_HUMAN,tr|A0A6Q8PF55|A0A6Q8PF55_HUMAN,tr|A0A6Q8PGT8|A0A6Q8PGT8_HUMAN,tr|A0A6Q8PFT9|A0A6Q8PFT9_HUMAN,tr|A0A6Q8PG02|A0A6Q8PG02_HUMAN,tr|A0A6Q8PFI6|A0A6Q8PFI6_HUMAN,tr|A0A6Q8PGW1|A0A6Q8PGW1_HUMAN" 13 1032.5638 999 61484 8776 2 1032.563805 517.2892 E3 ubiquitin-protein ligase LRSAM1 OS=Homo sapiens OX=9606 GN=LRSAM1 PE=1 SV=1 8.5 1964.8 - 427558 - - - 0.0378 - 1.632 0.13 - 326.8 1 2 1 0 8 0 0 0 6.15E+06 0.00E+00 - - - 1.4784 0.9999 221125_WJC_METTL3_EV_vs_WT_F05.08778.08778.2 7.44E-06 22-Oct K.TIDEGDADEVTK.Q sp|Q7LBC6|KDM3B_HUMAN 1 1291.578 1.32 61486 8778 2 1291.578536 646.7963 Lysine-specific demethylase 3B OS=Homo sapiens OX=9606 GN=KDM3B PE=1 SV=2 3.77 1965.1 - 238588 - - - 0.4491 - 2.034 0.608 - 148.8 1 2 0 0.0006 12 0 0 0 1.98E+07 1.49E+07 - - - 5.3996 0.9999 221125_WJC_METTL3_EV_vs_WT_F05.08783.08783.2 0.000113 20-Dec R.AEGLQVGQDAR.V "sp|Q8WWM7|ATX2L_HUMAN,tr|A0A0C4DGL7|A0A0C4DGL7_HUMAN,tr|H3BRB0|H3BRB0_HUMAN" 3 1142.568 1.41 61489 8783 2 1142.567871 572.2913 Ataxin-2-like protein OS=Homo sapiens OX=9606 GN=ATXN2L PE=1 SV=2 4.37 1965.8 - 1.57E+06 - - - -0.1129 - 2.448 0.418 - 432.3 1 2 0 -0.0001 11 0 0 0 2.72E+07 1.93E+07 - - - 4.5502 0.9999 221125_WJC_METTL3_EV_vs_WT_F05.08785.08785.2 5.75E-07 13/22 K.GSDGAASSYQLK.Q "sp|Q14203|DCTN1_HUMAN,tr|A0A804CDA6|A0A804CDA6_HUMAN,tr|E7EX90|E7EX90_HUMAN,tr|A0A7P0Z4C3|A0A7P0Z4C3_HUMAN,tr|Q6AWB1|Q6AWB1_HUMAN" 5 1182.5517 1.97 61491 8785 2 1182.55217 592.2831 Dynactin subunit 1 OS=Homo sapiens OX=9606 GN=DCTN1 PE=1 SV=3 5.83 1965.9 - 1.75E+06 - - - 0.4135 - 2.95 0.517 - 773.2 1 2 0 0.0005 12 0 0 0 7.71E+07 3.92E+07 - - - 5.7058 0.9629 221125_WJC_METTL3_EV_vs_WT_F05.08786.08786.2 0.0345 13/22 Q.ALEEANNDLENK.L sp|P35527|K1C9_HUMAN 1 1358.6314 999 61492 8786 2 1358.629905 680.323 "Keratin, type I cytoskeletal 9 OS=Homo sapiens OX=9606 GN=KRT9 PE=1 SV=3" 4 1966.1 - 748545 - - - -1.0915 - 2.772 0.172 - 543.1 1 1 0 -0.0015 12 0 0 0 1.03E+07 0.00E+00 - - - 2.9936 0.998 221125_WJC_METTL3_EV_vs_WT_F05.08787.08787.2 0.0394 18-Jul K.EKPTTALLDK.V "sp|Q12906|ILF3_HUMAN,tr|K7ER69|K7ER69_HUMAN,tr|K7EKY0|K7EKY0_HUMAN,tr|K7EKJ9|K7EKJ9_HUMAN" 4 1114.6234 1.02 61493 8787 2 1114.623375 558.319 Interleukin enhancer-binding factor 3 OS=Homo sapiens OX=9606 GN=ILF3 PE=1 SV=3 6.17 1966.2 - 681778 - - - -0.0135 - 1.404 0.264 - 90.6 2 2 0 0 10 0 0 0 3.29E+07 3.23E+07 - - - 1.8036 0.9998 221125_WJC_METTL3_EV_vs_WT_F05.08788.08788.2 0.00275 14-Oct K.HTDEEFLK[136.11].Q "sp|Q9H0C8|ILKAP_HUMAN,tr|E9PC05|E9PC05_HUMAN,tr|F8SNU7|F8SNU7_HUMAN,tr|H7C2I8|H7C2I8_HUMAN" 4 1025.4909 0.86 61494 8788 2 1025.49083 513.7527 Integrin-linked kinase-associated serine\threonine phosphatase 2C OS=Homo sapiens OX=9606 GN=ILKAP PE=1 SV=1 4.65 1966.3 - 394394 - - - -0.0926 - 1.945 0.438 - 273.7 1 2 0 -0.0001 8 0 0 0 8.26E+06 9.58E+06 - - - 4.2824 0.999 221125_WJC_METTL3_EV_vs_WT_F05.08794.08794.2 0.000628 16-Sep K.AQYEEIANR.S "sp|P13647|K2C5_HUMAN,tr|H0YI76|H0YI76_HUMAN,tr|H0YIN9|H0YIN9_HUMAN" 3 1092.52 1016.39 61498 8794 2 1092.52368 547.2673 "Keratin, type II cytoskeletal 5 OS=Homo sapiens OX=9606 GN=KRT5 PE=1 SV=3" 4.53 1967.1 - 2.47E+06 - - - 3.3803 - 1.806 0.497 - 455 1 2 0 0.0037 9 0 0 0 1.35E+09 1.33E+06 - - - 4.4208 0.9991 221125_WJC_METTL3_EV_vs_WT_F05.08795.08795.2 0.167 14-Oct K.QEIAEINR.M "sp|P48668|K2C6C_HUMAN,sp|P04259|K2C6B_HUMAN,sp|P02538|K2C6A_HUMAN" 3 971.5036 12.5 61499 8795 2 971.505055 486.7591 "Keratin, type II cytoskeletal 6C OS=Homo sapiens OX=9606 GN=KRT6C PE=1 SV=3" 4.53 1967.2 - 1.38E+06 - - - 1.4884 - 2.082 0.226 - 469.2 1 2 0 0.0014 8 0 0 0 1.05E+08 8.41E+06 - - - 2.9215 0.8333 221125_WJC_METTL3_EV_vs_WT_F05.08798.08798.2 0.983 16-Aug L.SNTSLLNSR.L sp|Q6P444|MTFR2_HUMAN 1 990.5094 13.83 61502 8798 2 990.509704 496.262 Mitochondrial fission regulator 2 OS=Homo sapiens OX=9606 GN=MTFR2 PE=1 SV=2 9.47 1967.5 - 626079 - - - 0.2837 - 1.616 0.135 - 291.7 1 1 0 0.0003 9 0 0 0 7.34E+06 5.31E+05 - - - 1.4266 0.9991 221125_WJC_METTL3_EV_vs_WT_F05.08800.08800.2 0.00453 18-Nov K.LYHNEVEIEK[136.11].L "sp|Q14683|SMC1A_HUMAN,tr|G8JLG1|G8JLG1_HUMAN" 2 1280.6492 2.34 61504 8800 2 1280.645685 641.3319 Structural maintenance of chromosomes protein 1A OS=Homo sapiens OX=9606 GN=SMC1A PE=1 SV=2 4.75 1967.8 - 457602 - - - -2.758 - 2.156 0.362 - 485.8 1 2 0 -0.0035 10 0 0 0 1.48E+07 6.32E+06 - - - 3.8581 0.9992 221125_WJC_METTL3_EV_vs_WT_F05.08801.08801.2 0.00274 18-Sep R.QQVVLENAAK[136.11].K sp|Q01780|EXOSX_HUMAN 1 1106.6175 1.33 61505 8801 2 1106.615814 554.316 Exosome component 10 OS=Homo sapiens OX=9606 GN=EXOSC10 PE=1 SV=2 6 1967.9 - 409376 - - - -1.5443 - 1.728 0.325 - 343.9 1 2 0 -0.0017 10 0 0 0 4.88E+06 3.66E+06 - - - 2.9677 0.9974 221125_WJC_METTL3_EV_vs_WT_F05.08804.08804.2 0.137 16-Aug K.SQNTVFC[160.03]GR[166.11].L "sp|Q96FV9|THOC1_HUMAN,tr|A0A087WWS1|A0A087WWS1_HUMAN,tr|A0A087WY84|A0A087WY84_HUMAN,tr|J3KT14|J3KT14_HUMAN" 4 1077.4901 2.16 61508 8804 2 1077.488713 539.7523 THO complex subunit 1 OS=Homo sapiens OX=9606 GN=THOC1 PE=1 SV=1 7.96 1968.3 - 195668 - - - -1.2854 - 1.562 0.204 - 307.4 1 2 0 -0.0014 9 0 0 0 6.18E+06 2.86E+06 - - - 1.8375 1 221125_WJC_METTL3_EV_vs_WT_F05.08807.08807.3 2.77E-06 13/44 K.EAPPMEKPEVVK.T "sp|P62841|RS15_HUMAN,tr|K7EJ78|K7EJ78_HUMAN,tr|K7EM56|K7EM56_HUMAN,tr|A0A0B4J2B4|A0A0B4J2B4_HUMAN,tr|S4R456|S4R456_HUMAN,tr|K7ELC2|K7ELC2_HUMAN,tr|K7EQJ5|K7EQJ5_HUMAN,tr|S4R417|S4R417_HUMAN" 8 1352.701 1.36 61510 8807 3 1352.702594 451.9076 40S ribosomal protein S15 OS=Homo sapiens OX=9606 GN=RPS15 PE=1 SV=2 4.79 1968.7 - 3.72E+06 - - - 1.1873 - 2.597 0.494 - 281.9 1 2 0 0.0016 12 0 0 0 1.32E+09 9.66E+08 - - - 6.6925 0.9997 221125_WJC_METTL3_EV_vs_WT_F05.08809.08809.3 0.0861 Nov-36 K.LYHNEVEIEK[136.11].L "sp|Q14683|SMC1A_HUMAN,tr|G8JLG1|G8JLG1_HUMAN" 2 1280.6492 0.97 61511 8809 3 1280.650103 427.8903 Structural maintenance of chromosomes protein 1A OS=Homo sapiens OX=9606 GN=SMC1A PE=1 SV=2 4.75 1968.9 - 6.79E+06 - - - 0.6918 - 2.063 0.32 - 264 1 2 0 0.0009 10 0 0 0 5.53E+07 5.70E+07 - - - 4.2223 1 221125_WJC_METTL3_EV_vs_WT_F05.08810.08810.3 1.62E-05 16/36 K.LYHNEVEIEK.L "sp|Q14683|SMC1A_HUMAN,tr|G8JLG1|G8JLG1_HUMAN" 2 1272.635 0.97 61512 8810 3 1272.636143 425.2189 Structural maintenance of chromosomes protein 1A OS=Homo sapiens OX=9606 GN=SMC1A PE=1 SV=2 4.75 1968.9 - 7.20E+06 - - - 0.8848 - 3.061 0.437 - 664.3 1 2 0 0.0011 10 0 0 0 5.53E+07 5.70E+07 - - - 6.679 1 221125_WJC_METTL3_EV_vs_WT_F05.08814.08814.3 3.74E-07 13/36 R.RPELEDSTLR.Y "sp|Q15149|PLEC_HUMAN,tr|E9PMV1|E9PMV1_HUMAN,tr|H0YDN1|H0YDN1_HUMAN" 3 1214.6255 1.41 61516 8814 3 1214.627842 405.8824 Plectin OS=Homo sapiens OX=9606 GN=PLEC PE=1 SV=3 4.68 1969.3 - 662274 - - - 1.9158 - 2.782 0.527 - 400.8 1 2 0 0.0023 10 0 0 0 7.77E+06 5.50E+06 - - - 7.403 0.9999 221125_WJC_METTL3_EV_vs_WT_F05.08815.08815.2 3.85E-10 15/24 K.VSVAVEASADSSK.T "sp|Q99590|SCAFB_HUMAN,tr|F8VXG7|F8VXG7_HUMAN,tr|A0A087WTB7|A0A087WTB7_HUMAN" 3 1248.6198 2.25 61517 8815 2 1248.618607 625.3172 Protein SCAF11 OS=Homo sapiens OX=9606 GN=SCAF11 PE=1 SV=2 4.37 1969.5 - 462551 - - - -0.9242 - 3.065 0.506 - 1171.1 1 2 0 -0.0012 13 0 0 0 2.72E+07 1.21E+07 - - - 5.6526 1 221125_WJC_METTL3_EV_vs_WT_F05.08817.08817.2 4.81E-08 15/26 K.AVTEQGAELSNEER.N "sp|P27348|1433T_HUMAN,tr|E9PG15|E9PG15_HUMAN" 2 1531.7114 1.15 61519 8817 2 1531.712525 766.863 14-3-3 protein theta OS=Homo sapiens OX=9606 GN=YWHAQ PE=1 SV=1 4.09 1969.7 - 361744 - - - 0.7149 - 3.209 0.682 - 758.3 1 2 0 0.0011 14 0 0 0 2.60E+07 2.27E+07 - - - 7.0038 0.9999 221125_WJC_METTL3_EV_vs_WT_F05.08818.08818.2 5.23E-09 13/26 K.AVTEQGAELSNEER[166.11].N "sp|P27348|1433T_HUMAN,tr|E9PG15|E9PG15_HUMAN" 2 1541.7197 1.15 61520 8818 2 1541.721119 771.8671 14-3-3 protein theta OS=Homo sapiens OX=9606 GN=YWHAQ PE=1 SV=1 4.09 1969.9 - 347241 - - - 0.9204 - 3.137 0.422 - 609.9 1 2 0 0.0014 14 0 0 0 2.60E+07 2.27E+07 - - - 5.0264 0.9999 221125_WJC_METTL3_EV_vs_WT_F05.08824.08824.3 3.55E-05 14/36 R.NGVMPSHFSR[166.11].G "sp|P39019|RS19_HUMAN,tr|A0A075B6E2|A0A075B6E2_HUMAN" 2 1140.5374 0.001 61524 8824 3 1140.538573 381.1864 40S ribosomal protein S19 OS=Homo sapiens OX=9606 GN=RPS19 PE=1 SV=2 9.76 1970.6 - 1.81E+06 - - - 1.0442 - 2.815 0.327 - 518.5 1 2 0 0.0012 10 0 0 0 0.00E+00 1.10E+08 - - - 5.2079 1 221125_WJC_METTL3_EV_vs_WT_F05.08826.08826.2 7.90E-08 22-Dec K.TIDEGDADEVTK[136.11].Q sp|Q7LBC6|KDM3B_HUMAN 1 1299.5922 1.57 61526 8826 2 1299.593522 650.8034 Lysine-specific demethylase 3B OS=Homo sapiens OX=9606 GN=KDM3B PE=1 SV=2 3.77 1970.7 - 1.21E+06 - - - 1.0511 - 2.353 0.631 - 243.4 1 2 0 0.0014 12 0 0 0 1.84E+07 1.17E+07 - - - 5.9526 0.9929 221125_WJC_METTL3_EV_vs_WT_F05.08827.08827.2 0.617 22-Jul K.YIC[160.03]ENQDSISSK.L "sp|P02768|ALBU_HUMAN,tr|B7WNR0|B7WNR0_HUMAN,tr|H0YA55|H0YA55_HUMAN,tr|A0A0C4DGB6|A0A0C4DGB6_HUMAN,tr|D6RHD5|D6RHD5_HUMAN,tr|C9JKR2|C9JKR2_HUMAN" 6 1442.6348 109.43 61527 8827 2 1442.634516 722.3247 Albumin OS=Homo sapiens OX=9606 GN=ALB PE=1 SV=2 4.37 1970.9 - 743059 - - - -0.1684 - 1.107 0.209 - 108.2 1 2 0 -0.0002 12 0 0 0 6.00E+06 5.49E+04 - - - 0.8521 0.9985 221125_WJC_METTL3_EV_vs_WT_F05.08831.08831.2 6.76E-05 18-Aug R.NGVMPSHFSR.G "sp|P39019|RS19_HUMAN,tr|A0A075B6E2|A0A075B6E2_HUMAN" 2 1130.5291 0.96 61531 8831 2 1130.526234 566.2718 40S ribosomal protein S19 OS=Homo sapiens OX=9606 GN=RPS19 PE=1 SV=2 9.76 1971.4 - 242980 - - - -2.5457 - 1.638 0.362 - 251.2 1 2 0 -0.0029 10 0 0 0 1.57E+07 1.64E+07 - - - 3.0913 0.9998 221125_WJC_METTL3_EV_vs_WT_F05.08832.08832.2 0.0054 20-Aug K.SQNEAVC[160.03]EGLR.T sp|O43663|PRC1_HUMAN 1 1261.5721 1.1 61532 8832 2 1261.572127 631.7933 Protein regulator of cytokinesis 1 OS=Homo sapiens OX=9606 GN=PRC1 PE=1 SV=2 4.53 1971.5 - 234182 - - - 0.0222 - 1.936 0.488 - 177 1 2 0 0 11 0 0 0 4.39E+06 4.01E+06 - - - 4.4325 0.9968 221125_WJC_METTL3_EV_vs_WT_F05.08834.08834.2 0.000893 22-Aug R.TYEPSSATPVTR[166.11].S "sp|P53804|TTC3_HUMAN,tr|H7C097|H7C097_HUMAN" 2 1317.644 0.2 61534 8834 2 1317.638981 659.8293 E3 ubiquitin-protein ligase TTC3 OS=Homo sapiens OX=9606 GN=TTC3 PE=1 SV=2 5.66 1971.8 - 147755 - - - -3.8205 - 1.402 0.451 - 187 1 2 0 -0.005 12 0 0 0 2.67E+05 1.32E+06 - - - 3.2596 0.9975 221125_WJC_METTL3_EV_vs_WT_F05.08838.08838.3 0.0257 Nov-36 R.LTEELKEQMK.A "sp|Q14683|SMC1A_HUMAN,tr|G8JLG1|G8JLG1_HUMAN,tr|A0A6Q8PHC3|A0A6Q8PHC3_HUMAN" 3 1247.6431 3.1 61536 8838 3 1247.644498 416.8883 Structural maintenance of chromosomes protein 1A OS=Homo sapiens OX=9606 GN=SMC1A PE=1 SV=2 4.79 1972.3 - 1.42E+06 - - - 1.0893 - 2.067 0.287 - 226.5 1 2 1 0.0014 10 0 0 0 3.99E+07 1.29E+07 - - - 3.8599 0.9999 221125_WJC_METTL3_EV_vs_WT_F05.08841.08841.3 0.00111 17/40 R.IYNDDKNTYIR.Y sp|O75533|SF3B1_HUMAN 1 1413.6888 1.15 61539 8841 3 1413.689991 472.2369 Splicing factor 3B subunit 1 OS=Homo sapiens OX=9606 GN=SF3B1 PE=1 SV=3 5.96 1972.5 - 896118 - - - 0.8114 - 2.951 0.524 - 430.4 1 2 1 0.0011 11 0 0 0 3.09E+07 2.69E+07 - - - 7.456 1 221125_WJC_METTL3_EV_vs_WT_F05.08843.08843.3 1.09E-06 Dec-52 K.AVTEQGAELSNEER.N "sp|P27348|1433T_HUMAN,tr|E9PG15|E9PG15_HUMAN" 2 1531.7114 1.1 61541 8843 3 1531.712945 511.5778 14-3-3 protein theta OS=Homo sapiens OX=9606 GN=YWHAQ PE=1 SV=1 4.09 1972.8 - 664980 - - - 0.9891 - 2.562 0.486 - 158.2 1 2 0 0.0015 14 0 0 0 5.89E+06 5.34E+06 - - - 6.4582 0.9999 221125_WJC_METTL3_EV_vs_WT_F05.08844.08844.3 0.000769 15/40 R.TAATLATHELR[166.11].A sp|Q8N1G4|LRC47_HUMAN 1 1192.644 3.12 61542 8844 3 1192.642879 398.5553 Leucine-rich repeat-containing protein 47 OS=Homo sapiens OX=9606 GN=LRRC47 PE=1 SV=1 6.41 1972.9 - 634296 - - - -0.903 - 2.558 0.34 - 278 1 2 0 -0.0011 11 0 0 0 2.83E+07 9.07E+06 - - - 4.9985 0.9998 221125_WJC_METTL3_EV_vs_WT_F05.08845.08845.3 0.0032 Dec-52 K.AVTEQGAELSNEER[166.11].N "sp|P27348|1433T_HUMAN,tr|E9PG15|E9PG15_HUMAN" 2 1541.7197 1.1 61543 8845 3 1541.721153 514.9138 14-3-3 protein theta OS=Homo sapiens OX=9606 GN=YWHAQ PE=1 SV=1 4.09 1973 - 595282 - - - 0.9425 - 2.32 0.356 - 231.9 1 2 0 0.0015 14 0 0 0 5.89E+06 5.34E+06 - - - 4.7451 0.9971 221125_WJC_METTL3_EV_vs_WT_F05.08847.08847.2 0.000104 20-Dec K.ALQQEQEIEQR.L "sp|Q86YP4|P66A_HUMAN,sp|Q8WXI9|P66B_HUMAN,tr|A0A0U1RRM1|A0A0U1RRM1_HUMAN,tr|A0A0U1RR30|A0A0U1RR30_HUMAN" 4 1370.679 1.8 61545 8847 2 1370.684593 686.3468 Transcriptional repressor p66-alpha OS=Homo sapiens OX=9606 GN=GATAD2A PE=1 SV=1 4.25 1973.2 - 594930 - - - 4.0754 - 2.395 0.301 - 657.7 1 2 0 0.0056 11 0 0 0 2.89E+08 1.61E+08 - - - 3.6251 1 221125_WJC_METTL3_EV_vs_WT_F05.08848.08848.3 0.000113 Oct-36 R.R[166.11]PELEDSTLR[166.11].Y "sp|Q15149|PLEC_HUMAN,tr|E9PMV1|E9PMV1_HUMAN,tr|H0YDN1|H0YDN1_HUMAN" 3 1234.6421 1.91 61546 8848 3 1234.643671 412.5546 Plectin OS=Homo sapiens OX=9606 GN=PLEC PE=1 SV=3 4.68 1973.4 - 535324 - - - 1.3089 - 2.369 0.464 - 205.2 1 2 0 0.0016 10 0 0 0 7.50E+06 3.92E+06 - - - 6.2315 0.9998 221125_WJC_METTL3_EV_vs_WT_F05.08849.08849.2 0.000222 18-Jul R.NGVMPSHFSR[166.11].G "sp|P39019|RS19_HUMAN,tr|A0A075B6E2|A0A075B6E2_HUMAN" 2 1140.5374 0.97 61547 8849 2 1140.537958 571.276 40S ribosomal protein S19 OS=Homo sapiens OX=9606 GN=RPS19 PE=1 SV=2 9.76 1973.5 - 488568 - - - 0.505 - 1.621 0.51 - 173.3 1 2 0 0.0006 10 0 0 0 1.57E+07 1.61E+07 - - - 4.156 0.9996 221125_WJC_METTL3_EV_vs_WT_F05.08850.08850.2 0.00159 16-Oct R.KMTPSYEIR.A sp|Q08211|DHX9_HUMAN 1 1123.5696 0.04 61548 8850 2 1123.569308 562.7921 ATP-dependent RNA helicase A OS=Homo sapiens OX=9606 GN=DHX9 PE=1 SV=4 8.59 1973.6 - 361742 - - - -0.2421 - 1.981 0.297 - 396.7 1 2 0 -0.0003 9 0 0 0 3.77E+06 8.70E+07 - - - 3.2123 0.9998 221125_WJC_METTL3_EV_vs_WT_F05.08854.08854.2 7.78E-05 20-Sep K.VQENSAYIC[160.03]SR[166.11].R sp|Q9Y3T9|NOC2L_HUMAN 1 1335.6117 1.11 61552 8854 2 1335.610556 668.8131 Nucleolar complex protein 2 homolog OS=Homo sapiens OX=9606 GN=NOC2L PE=1 SV=4 5.97 1974.1 - 333405 - - - -0.8341 - 1.885 0.498 - 200.2 1 2 0 -0.0011 11 0 0 0 5.06E+06 4.54E+06 - - - 4.4338 0.9997 221125_WJC_METTL3_EV_vs_WT_F05.08856.08856.2 7.08E-05 20-Nov K.IANPVEGSTDR.Q "sp|Q15366|PCBP2_HUMAN,tr|F8VRH0|F8VRH0_HUMAN,tr|F8VZX2|F8VZX2_HUMAN,tr|H3BRU6|H3BRU6_HUMAN,tr|H3BSS4|H3BSS4_HUMAN" 5 1157.5677 1.26 61553 8856 2 1157.568727 579.7911 Poly(rC)-binding protein 2 OS=Homo sapiens OX=9606 GN=PCBP2 PE=1 SV=1 4.37 1974.4 - 2.08E+06 - - - 0.9166 - 2.165 0.4 - 496.5 1 2 0 0.0011 11 0 0 0 6.59E+08 5.21E+08 - - - 4.0846 0.9997 221125_WJC_METTL3_EV_vs_WT_F05.08857.08857.2 0.00257 13/20 K.IANPVEGSTDR[166.11].Q "sp|Q15366|PCBP2_HUMAN,tr|F8VRH0|F8VRH0_HUMAN,tr|F8VZX2|F8VZX2_HUMAN,tr|H3BRU6|H3BRU6_HUMAN,tr|H3BSS4|H3BSS4_HUMAN" 5 1167.5759 1.26 61554 8857 2 1167.576079 584.7952 Poly(rC)-binding protein 2 OS=Homo sapiens OX=9606 GN=PCBP2 PE=1 SV=1 4.37 1974.4 - 1.48E+06 - - - 0.1225 - 2.161 0.339 - 509.1 1 2 0 0.0001 11 0 0 0 6.59E+08 5.21E+08 - - - 3.6294 0.9995 221125_WJC_METTL3_EV_vs_WT_F05.08858.08858.2 0.0852 14/20 K.ALQQEQEIEQR[166.11].L "sp|Q86YP4|P66A_HUMAN,sp|Q8WXI9|P66B_HUMAN,tr|A0A0U1RRM1|A0A0U1RRM1_HUMAN,tr|A0A0U1RR30|A0A0U1RR30_HUMAN" 4 1380.6873 1.79 61555 8858 2 1380.686942 691.3509 Transcriptional repressor p66-alpha OS=Homo sapiens OX=9606 GN=GATAD2A PE=1 SV=1 4.25 1974.5 - 3.64E+06 - - - -0.2426 - 2.329 0.235 - 1162.5 1 2 0 -0.0003 11 0 0 0 2.89E+08 1.61E+08 - - - 3.0637 0.9998 221125_WJC_METTL3_EV_vs_WT_F05.08860.08860.3 1.16E-05 Dec-40 R.IYNDDK[136.11]NTYIR[166.11].Y sp|O75533|SF3B1_HUMAN 1 1431.7113 1.36 61557 8860 3 1431.709709 478.2444 Splicing factor 3B subunit 1 OS=Homo sapiens OX=9606 GN=SF3B1 PE=1 SV=3 5.96 1974.6 - 2.83E+06 - - - -1.121 - 2.544 0.471 - 195.1 1 2 1 -0.0016 11 0 0 0 3.68E+07 2.71E+07 - - - 6.4433 0.9996 221125_WJC_METTL3_EV_vs_WT_F05.08861.08861.2 0.000668 14-Aug R.K[136.11]YGLNMC[160.03]R[166.11].Q "sp|P62273|RS29_HUMAN,tr|A0A2R8Y6P7|A0A2R8Y6P7_HUMAN,tr|A0A2R8Y851|A0A2R8Y851_HUMAN,tr|A0A087WTT6|A0A087WTT6_HUMAN" 4 1058.512 1.1 61558 8861 2 1058.51328 530.2633 40S ribosomal protein S29 OS=Homo sapiens OX=9606 GN=RPS29 PE=1 SV=2 9.31 1974.6 - 2.63E+06 - - - 1.1847 - 1.807 0.401 - 238.8 1 2 0 0.0013 8 0 0 0 2.20E+08 2.00E+08 - - - 3.7868 0.9999 221125_WJC_METTL3_EV_vs_WT_F05.08862.08862.2 1.13E-05 24-Nov K.GPGEVAGTVTGQK[136.11].R "sp|Q86U44|MTA70_HUMAN,tr|F5H6D8|F5H6D8_HUMAN,tr|H0YFV6|H0YFV6_HUMAN,tr|B4DTN4|B4DTN4_HUMAN" 4 1207.6288 0.03 61559 8862 2 1207.628235 604.8217 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 6 1974.7 - 2.38E+06 - - - -0.4811 - 2.354 0.497 - 454.6 1 2 0 -0.0006 13 0 0 0 3.79E+09 1.37E+11 - - - 4.9089 0.9998 221125_WJC_METTL3_EV_vs_WT_F05.08863.08863.2 0.000177 14-Oct R.KYGLNMC[160.03]R.Q "sp|P62273|RS29_HUMAN,tr|A0A2R8Y6P7|A0A2R8Y6P7_HUMAN,tr|A0A2R8Y851|A0A2R8Y851_HUMAN,tr|A0A087WTT6|A0A087WTT6_HUMAN" 4 1040.4896 1.1 61560 8863 2 1040.488547 521.2521 40S ribosomal protein S29 OS=Homo sapiens OX=9606 GN=RPS29 PE=1 SV=2 9.31 1974.7 - 2.05E+06 - - - -0.9697 - 1.939 0.496 - 385.3 1 2 0 -0.001 8 0 0 0 2.20E+08 2.00E+08 - - - 4.7012 0.9969 221125_WJC_METTL3_EV_vs_WT_F05.08864.08864.2 0.000699 14-Oct R.DALK[136.11]TEFK[136.11].A "sp|Q5VTU8|AT5EL_HUMAN,sp|P56381|ATP5E_HUMAN" 2 966.5357 1.33 61561 8864 2 966.535237 484.2751 "ATP synthase subunit epsilon-like protein, mitochondrial OS=Homo sapiens OX=9606 GN=ATP5F1EP2 PE=1 SV=1" 6.07 1974.8 - 1.97E+06 - - - -0.4759 - 1.761 0.401 - 390.9 1 2 1 -0.0005 8 0 0 0 3.78E+07 2.84E+07 - - - 3.7093 0.9981 221125_WJC_METTL3_EV_vs_WT_F05.08866.08866.3 0.0369 Sep-40 K.ALQQEQEIEQR.L "sp|Q86YP4|P66A_HUMAN,sp|Q8WXI9|P66B_HUMAN,tr|A0A0U1RRM1|A0A0U1RRM1_HUMAN,tr|A0A0U1RR30|A0A0U1RR30_HUMAN" 4 1370.679 1.76 61563 8866 3 1370.678199 457.9003 Transcriptional repressor p66-alpha OS=Homo sapiens OX=9606 GN=GATAD2A PE=1 SV=1 4.25 1974.9 - 1.65E+06 - - - -0.5895 - 1.736 0.248 - 186.6 1 2 0 -0.0008 11 0 0 0 6.94E+07 3.95E+07 - - - 2.8717 0.9997 221125_WJC_METTL3_EV_vs_WT_F05.08867.08867.3 0.000607 Nov-44 K.VSYARPSSEVIK.D "sp|Q15717|ELAV1_HUMAN,tr|M0R055|M0R055_HUMAN,tr|M0QZR9|M0QZR9_HUMAN" 3 1334.7194 1.35 61564 8867 3 1334.720628 445.9137 ELAV-like protein 1 OS=Homo sapiens OX=9606 GN=ELAVL1 PE=1 SV=2 8.56 1975 - 1.20E+06 - - - 0.9088 - 2.111 0.341 - 156.1 1 2 0 0.0012 12 0 0 0 7.77E+07 5.77E+07 - - - 4.4125 0.9998 221125_WJC_METTL3_EV_vs_WT_F05.08868.08868.2 1.81E-07 20-Dec K.AYTGFSSNSER[166.11].G sp|O15355|PPM1G_HUMAN 1 1227.5395 0.55 61565 8868 2 1227.538629 614.7771 Protein phosphatase 1G OS=Homo sapiens OX=9606 GN=PPM1G PE=1 SV=1 6.05 1975.1 - 1.18E+06 - - - -0.7503 - 2.357 0.43 - 504.8 1 2 0 -0.0009 11 0 0 0 8.87E+06 1.61E+07 - - - 4.5361 0.9975 221125_WJC_METTL3_EV_vs_WT_F05.08871.08871.2 0.3 14-Jul R.ETIQNLSR.L "sp|Q15643|TRIPB_HUMAN,tr|H0YJ97|H0YJ97_HUMAN" 2 959.5036 1.01 61568 8871 2 959.501743 480.7591 Thyroid receptor-interacting protein 11 OS=Homo sapiens OX=9606 GN=TRIP11 PE=1 SV=3 6.1 1975.5 - 850235 - - - -1.9448 - 1.705 0.213 - 145.8 1 2 0 -0.0019 8 0 0 0 6.11E+06 6.06E+06 - - - 2.2228 0.9998 221125_WJC_METTL3_EV_vs_WT_F05.08872.08872.2 0.0094 20-Oct K.AYTGFSSNSER.G sp|O15355|PPM1G_HUMAN 1 1217.5313 0.55 61569 8872 2 1217.53037 609.7729 Protein phosphatase 1G OS=Homo sapiens OX=9606 GN=PPM1G PE=1 SV=1 6.05 1975.6 - 626866 - - - -0.7474 - 1.776 0.493 - 264.3 1 2 0 -0.0009 11 0 0 0 8.87E+06 1.61E+07 - - - 4.2358 0.9363 221125_WJC_METTL3_EV_vs_WT_F05.08874.08874.2 5.36E-08 13/22 V.NAAQDSTDLVAK[136.11].L "sp|P17987|TCPA_HUMAN,tr|F5H282|F5H282_HUMAN,tr|E7EQR6|E7EQR6_HUMAN" 3 1239.6186 0.54 61571 8874 2 1239.613718 620.8166 T-complex protein 1 subunit alpha OS=Homo sapiens OX=9606 GN=TCP1 PE=1 SV=1 4.21 1975.9 - 373041 - - - -3.9746 - 2.54 0.45 - 593.7 1 1 0 -0.0049 12 0 0 0 1.37E+07 2.55E+07 - - - 4.8158 0.9039 221125_WJC_METTL3_EV_vs_WT_F05.08878.08878.2 0.00827 16-Jul N.GVMPSHFSR.G "sp|P39019|RS19_HUMAN,tr|A0A075B6E2|A0A075B6E2_HUMAN" 2 1016.4862 0.5 61574 8878 2 1016.487727 509.2504 40S ribosomal protein S19 OS=Homo sapiens OX=9606 GN=RPS19 PE=1 SV=2 9.76 1976.4 - 367721 - - - 1.517 - 1.428 0.309 - 172.8 1 1 0 0.0015 9 0 0 0 3.63E+06 7.33E+06 - - - 2.3535 0.9997 221125_WJC_METTL3_EV_vs_WT_F05.08879.08879.3 0.000668 Oct-40 K.LDAQVQELHAK[136.11].V sp|P35580|MYH10_HUMAN 1 1258.6761 1.02 61575 8879 3 1258.676638 420.566 Myosin-10 OS=Homo sapiens OX=9606 GN=MYH10 PE=1 SV=3 5.32 1976.5 - 3.81E+06 - - - 0.4274 - 2.022 0.328 - 212.3 1 2 0 0.0005 11 0 0 0 3.08E+07 3.02E+07 - - - 4.1969 0.9985 221125_WJC_METTL3_EV_vs_WT_F05.08880.08880.3 0.181 Oct-40 K.ALQQEQEIEQR[166.11].L "sp|Q86YP4|P66A_HUMAN,sp|Q8WXI9|P66B_HUMAN,tr|A0A0U1RRM1|A0A0U1RRM1_HUMAN,tr|A0A0U1RR30|A0A0U1RR30_HUMAN" 4 1380.6873 1.76 61576 8880 3 1380.685924 461.2364 Transcriptional repressor p66-alpha OS=Homo sapiens OX=9606 GN=GATAD2A PE=1 SV=1 4.25 1976.5 - 2.98E+06 - - - -0.9799 - 1.87 0.244 - 256.3 1 2 0 -0.0014 11 0 0 0 6.94E+07 3.95E+07 - - - 3.0382 0.9991 221125_WJC_METTL3_EV_vs_WT_F05.08882.08882.3 0.00479 Sep-44 K.VSYAR[166.11]PSSEVIK[136.11].D "sp|Q15717|ELAV1_HUMAN,tr|M0R055|M0R055_HUMAN,tr|M0QZR9|M0QZR9_HUMAN" 3 1352.7419 1.35 61578 8882 3 1352.741288 451.9212 ELAV-like protein 1 OS=Homo sapiens OX=9606 GN=ELAVL1 PE=1 SV=2 8.56 1976.6 - 2.43E+06 - - - -0.4413 - 1.728 0.3 - 128.2 1 2 0 -0.0006 12 0 0 0 7.77E+07 5.77E+07 - - - 3.4006 0.9848 221125_WJC_METTL3_EV_vs_WT_F05.08883.08883.3 0.0375 Nov-40 K.TKEGVLYVGSK.T "sp|Q16143|SYUB_HUMAN,sp|P37840|SYUA_HUMAN,tr|A0A669KB41|A0A669KB41_HUMAN,tr|D6RA31|D6RA31_HUMAN,tr|A0A669KBH5|A0A669KBH5_HUMAN,tr|E7EPV7|E7EPV7_HUMAN" 6 1179.6499 1.7 61579 8883 3 1179.649015 394.2239 Beta-synuclein OS=Homo sapiens OX=9606 GN=SNCB PE=1 SV=1 8.17 1976.7 - 1.37E+06 - - - -0.7833 - 1.403 0.268 - 128.2 1 2 1 -0.0009 11 0 0 0 2.41E+07 1.42E+07 - - - 2.4896 0.9847 221125_WJC_METTL3_EV_vs_WT_F05.08884.08884.3 0.0228 Dec-40 K.TK[136.11]EGVLYVGSK[136.11].T "sp|Q16143|SYUB_HUMAN,sp|P37840|SYUA_HUMAN,tr|A0A669KB41|A0A669KB41_HUMAN,tr|D6RA31|D6RA31_HUMAN,tr|A0A669KBH5|A0A669KBH5_HUMAN,tr|E7EPV7|E7EPV7_HUMAN" 6 1195.6783 1.68 61580 8884 3 1195.676815 399.5667 Beta-synuclein OS=Homo sapiens OX=9606 GN=SNCB PE=1 SV=1 8.17 1976.8 - 1.20E+06 - - - -1.2746 - 1.815 0.21 - 193.5 1 2 1 -0.0015 11 0 0 0 2.38E+07 1.41E+07 - - - 2.5742 0.9926 221125_WJC_METTL3_EV_vs_WT_F05.08885.08885.2 0.0429 22-Jul K.SMEASVDVSAPK.V sp|Q8IVF2|AHNK2_HUMAN 1 1219.5755 10.41 61581 8885 2 1219.578943 610.795 Protein AHNAK2 OS=Homo sapiens OX=9606 GN=AHNAK2 PE=1 SV=2 4.37 1976.9 - 1.00E+06 - - - 2.8617 - 1.345 0.279 - 78.4 1 2 0 0.0035 12 0 0 0 5.14E+07 4.94E+06 - - - 1.8805 0.9998 221125_WJC_METTL3_EV_vs_WT_F05.08886.08886.3 0.00154 Nov-36 R.IGNSYFK[136.11]EEK[136.11].Y sp|P31948|STIP1_HUMAN 1 1229.6263 1.04 61582 8886 3 1229.625688 410.8827 Stress-induced-phosphoprotein 1 OS=Homo sapiens OX=9606 GN=STIP1 PE=1 SV=1 6.14 1977 - 795622 - - - -0.5002 - 2.356 0.447 - 109.3 1 2 1 -0.0006 10 0 0 0 1.86E+07 1.78E+07 - - - 6.0262 0.9995 221125_WJC_METTL3_EV_vs_WT_F05.08887.08887.3 0.00251 Oct-44 K.AVMSNLSAHGVK[136.11].L sp|Q92616|GCN1_HUMAN 1 1220.6427 1.07 61583 8887 3 1220.640818 407.8882 eIF-2-alpha kinase activator GCN1 OS=Homo sapiens OX=9606 GN=GCN1 PE=1 SV=6 8.8 1977.1 - 633860 - - - -1.5353 - 1.97 0.329 - 88 1 2 0 -0.0019 12 0 0 0 8.47E+06 7.89E+06 - - - 4.0869 0.9987 221125_WJC_METTL3_EV_vs_WT_F05.08888.08888.2 0.00689 16-Jun K.AQYEDIAQK.S sp|P04264|K2C1_HUMAN 1 1064.5138 57.09 61584 8888 2 1064.513467 533.2642 "Keratin, type II cytoskeletal 1 OS=Homo sapiens OX=9606 GN=KRT1 PE=1 SV=6" 4.37 1977.2 - 604223 - - - -0.3495 - 1.308 0.318 - 125.4 1 2 0 -0.0004 9 0 0 0 7.67E+06 1.34E+05 - - - 2.1664 0.9994 221125_WJC_METTL3_EV_vs_WT_F05.08889.08889.2 0.00218 20-Aug K.IDMSSNNGC[160.03]MR.D "sp|P07814|SYEP_HUMAN,tr|V9GYZ6|V9GYZ6_HUMAN" 2 1283.5057 0.8 61585 8889 2 1283.509342 642.7601 Bifunctional glutamate\proline--tRNA ligase OS=Homo sapiens OX=9606 GN=EPRS1 PE=1 SV=5 5.83 1977.4 - 202334 - - - 2.8562 - 1.931 0.508 - 102.7 1 2 0 0.0037 11 0 0 0 2.16E+06 2.71E+06 - - - 4.5721 0.9967 221125_WJC_METTL3_EV_vs_WT_F05.08892.08892.2 0.0627 20-Jul K.SISNPPGSNLR.T "sp|Q9H4A3|WNK1_HUMAN,tr|F5GWT4|F5GWT4_HUMAN,tr|A0A6Q8PFM0|A0A6Q8PFM0_HUMAN" 3 1140.5887 1.58 61586 8892 2 1140.589161 571.3016 Serine\threonine-protein kinase WNK1 OS=Homo sapiens OX=9606 GN=WNK1 PE=1 SV=2 9.47 1977.8 - 3.37E+06 - - - 0.3726 - 1.414 0.198 - 118.1 1 2 0 0.0004 11 0 0 0 1.53E+08 9.64E+07 - - - 1.4404 0.994 221125_WJC_METTL3_EV_vs_WT_F05.08895.08895.3 0.00787 Aug-36 R.IGNSYFKEEK.Y sp|P31948|STIP1_HUMAN 1 1213.5979 0.98 61589 8895 3 1213.59499 405.5399 Stress-induced-phosphoprotein 1 OS=Homo sapiens OX=9606 GN=STIP1 PE=1 SV=1 6.14 1978 - 1.40E+06 - - - -2.4003 - 1.867 0.304 - 56.8 1 2 1 -0.0029 10 0 0 0 1.88E+07 1.91E+07 - - - 3.7518 0.9989 221125_WJC_METTL3_EV_vs_WT_F05.08898.08898.2 0.000784 16-Jul R.DFAPPGQQK[136.11].R sp|Q9BVC6|TM109_HUMAN 1 994.4963 0.78 61592 8898 2 994.497548 498.2554 Transmembrane protein 109 OS=Homo sapiens OX=9606 GN=TMEM109 PE=1 SV=1 5.84 1978.3 - 879259 - - - 1.2097 - 1.406 0.356 - 165.4 1 2 0 0.0012 9 0 0 0 1.77E+07 2.28E+07 - - - 2.6558 0.9954 221125_WJC_METTL3_EV_vs_WT_F05.08900.08900.2 0.000105 16-Sep K.SETSWESPK.Q "sp|Q86UE4|LYRIC_HUMAN,tr|E5RJU9|E5RJU9_HUMAN" 2 1049.4666 1.7 61594 8900 2 1049.461657 525.7406 Protein LYRIC OS=Homo sapiens OX=9606 GN=MTDH PE=1 SV=2 4.53 1978.4 - 750955 - - - -4.6671 - 1.585 0.432 - 339.1 1 2 0 -0.0049 9 0 0 0 1.28E+07 7.50E+06 - - - 3.5627 0.9871 221125_WJC_METTL3_EV_vs_WT_F05.08902.08902.2 0.000124 16-Sep V.GESVFHTTR.W sp|Q9P0J0|NDUAD_HUMAN 1 1032.4989 45.76 61596 8902 2 1032.498477 517.2567 NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 13 OS=Homo sapiens OX=9606 GN=NDUFA13 PE=1 SV=3 6.75 1978.7 - 521154 - - - -0.369 - 1.929 0.412 - 527.9 1 1 0 -0.0004 9 0 0 0 4.57E+06 9.99E+04 - - - 3.9847 0.8943 221125_WJC_METTL3_EV_vs_WT_F05.08905.08905.2 0.535 20-Aug K.SISNPPGSNLR[166.11].T "sp|Q9H4A3|WNK1_HUMAN,tr|F5GWT4|F5GWT4_HUMAN,tr|A0A6Q8PFM0|A0A6Q8PFM0_HUMAN" 3 1150.597 1.59 61597 8905 2 1150.60235 576.3058 Serine\threonine-protein kinase WNK1 OS=Homo sapiens OX=9606 GN=WNK1 PE=1 SV=2 9.47 1979.1 - 4.98E+06 - - - 4.6445 - 1.377 0.14 - 163.2 2 2 0 0.0053 11 0 0 0 1.52E+08 9.55E+07 - - - 0.8043 0.9998 221125_WJC_METTL3_EV_vs_WT_F05.08906.08906.2 0.000624 16-Oct K.EVDEDFDSK.L "sp|Q96C19|EFHD2_HUMAN,tr|H0Y4Y4|H0Y4Y4_HUMAN" 2 1082.4404 1.12 61598 8906 2 1082.440432 542.2275 EF-hand domain-containing protein D2 OS=Homo sapiens OX=9606 GN=EFHD2 PE=1 SV=1 3.77 1979.2 - 863504 - - - 0.0296 - 1.715 0.457 - 373.8 1 2 0 0 9 0 0 0 1.00E+07 8.95E+06 - - - 3.9769 0.9931 221125_WJC_METTL3_EV_vs_WT_F05.08908.08908.2 7.69E-05 18-Oct K.EYNVNDDSMK.L "sp|Q14527|HLTF_HUMAN,tr|A0A0C4DGA6|A0A0C4DGA6_HUMAN" 2 1213.4921 3.52 61600 8908 2 1214.495788 607.7533 Helicase-like transcription factor OS=Homo sapiens OX=9606 GN=HLTF PE=1 SV=2 4.03 1979.4 - 1.07E+06 - - - 827.0923 - 1.592 0.588 - 394.5 1 2 0 1.0037 10 0 0 0 3.17E+07 9.01E+06 - - - 4.3667 0.9999 221125_WJC_METTL3_EV_vs_WT_F05.08910.08910.2 7.73E-07 18-Dec K.TPASPVVHIR.G "sp|P14866|HNRPL_HUMAN,tr|M0QYL7|M0QYL7_HUMAN,tr|M0R1W6|M0R1W6_HUMAN,tr|A0A3B3ITJ4|A0A3B3ITJ4_HUMAN,tr|M0QXS5|M0QXS5_HUMAN" 5 1075.6138 1.58 61602 8910 2 1075.61292 538.8142 Heterogeneous nuclear ribonucleoprotein L OS=Homo sapiens OX=9606 GN=HNRNPL PE=1 SV=2 9.44 1979.6 - 507851 - - - -0.8442 - 2.557 0.521 - 744 1 2 0 -0.0009 10 0 0 0 9.82E+06 6.22E+06 - - - 5.5094 0.9999 221125_WJC_METTL3_EV_vs_WT_F05.08911.08911.2 7.76E-07 26-Dec K.ATSSATTAAAPTLR.R "sp|Q8N9M1|CS047_HUMAN,tr|J3QS80|J3QS80_HUMAN,tr|A0A2R8Y6U9|A0A2R8Y6U9_HUMAN,tr|A0A804HLH2|A0A804HLH2_HUMAN" 4 1317.6888 1.1 61603 8911 2 1317.687902 659.8517 Uncharacterized protein C19orf47 OS=Homo sapiens OX=9606 GN=C19orf47 PE=1 SV=1 9.79 1979.7 - 438421 - - - -0.7149 - 2.797 0.545 - 538.8 1 2 0 -0.0009 14 0 0 0 1.66E+07 1.51E+07 - - - 5.6472 0.9958 221125_WJC_METTL3_EV_vs_WT_F05.08912.08912.2 1.72 22-Aug K.VSYARPSSEVIK.D "sp|Q15717|ELAV1_HUMAN,tr|M0R055|M0R055_HUMAN,tr|M0QZR9|M0QZR9_HUMAN" 3 1334.7194 1.55 61604 8912 2 1334.721266 668.367 ELAV-like protein 1 OS=Homo sapiens OX=9606 GN=ELAVL1 PE=1 SV=2 8.56 1979.8 - 257562 - - - 1.3868 - 1.634 0.169 - 137.1 1 2 0 0.0019 12 0 0 0 5.46E+06 3.52E+06 - - - 1.5806 1 221125_WJC_METTL3_EV_vs_WT_F05.08913.08913.2 2.43E-11 24-Dec K.VIEC[160.03]SYTSADGQR[166.11].H "sp|Q9UBM7|DHCR7_HUMAN,tr|A0A804HI25|A0A804HI25_HUMAN,tr|A0A804HJQ7|A0A804HJQ7_HUMAN,tr|H0YE57|H0YE57_HUMAN" 4 1494.6648 0.88 61605 8913 2 1494.664977 748.3397 7-dehydrocholesterol reductase OS=Homo sapiens OX=9606 GN=DHCR7 PE=1 SV=1 4.37 1979.9 - 218888 - - - 0.1004 - 2.551 0.712 - 538.5 1 2 0 0.0001 13 0 0 0 5.58E+06 6.37E+06 - - - 6.7033 0.9913 221125_WJC_METTL3_EV_vs_WT_F05.08920.08920.3 0.0364 18/44 A.SAHLPAPAAVGR[166.11].R sp|Q8ND56|LS14A_HUMAN 1 1155.6388 1.87 61610 8920 3 1155.638767 386.2202 Protein LSM14 homolog A OS=Homo sapiens OX=9606 GN=LSM14A PE=1 SV=3 9.49 1980.7 - 1.48E+06 - - - -0.0381 - 3.041 0.336 - 706.1 1 1 0 0 12 0 0 0 1.26E+08 6.72E+07 - - - 5.3689 0.9967 221125_WJC_METTL3_EV_vs_WT_F05.08922.08922.2 0.113 16-Aug R.KQC[160.03]ALAALR.D "sp|Q16875|F263_HUMAN,sp|Q16877|F264_HUMAN,tr|A0A1W2PR17|A0A1W2PR17_HUMAN,tr|Q66S35|Q66S35_HUMAN,tr|Q5W015|Q5W015_HUMAN,tr|A0A1W2PNV9|A0A1W2PNV9_HUMAN,tr|C9JJ23|C9JJ23_HUMAN,tr|C9JX77|C9JX77_HUMAN,tr|C9K0D8|C9K0D8_HUMAN,tr|F2Z2I2|F2Z2I2_HUMAN,tr|Q5VX20|Q5VX20_HUMAN" 11 1029.5753 4.87 61612 8922 2 1029.577104 515.7949 "6-phosphofructo-2-kinase\fructose-2,6-bisphosphatase 3 OS=Homo sapiens OX=9606 GN=PFKFB3 PE=1 SV=1" 9.51 1980.9 - 649600 - - - 1.7192 - 1.92 0.153 - 222.2 2 2 0 0.0018 9 0 0 0 2.05E+07 4.21E+06 - - - 1.9232 0.9998 221125_WJC_METTL3_EV_vs_WT_F05.08923.08923.2 1.32E-05 15/28 R.FGQGGAGPVGGQGPR[166.11].G sp|P23246|SFPQ_HUMAN 1 1350.6668 0.87 61613 8923 2 1350.669773 676.3407 "Splicing factor, proline- and glutamine-rich OS=Homo sapiens OX=9606 GN=SFPQ PE=1 SV=2" 9.75 1981.1 - 492678 - - - 2.1893 - 3.012 0.527 - 717.4 1 2 0 0.003 15 0 0 0 3.20E+08 3.68E+08 - - - 5.6433 0.9999 221125_WJC_METTL3_EV_vs_WT_F05.08929.08929.2 1.76E-05 18-Oct R.TEYLSNADER.L "sp|Q14204|DYHC1_HUMAN,tr|A0A7P0T8N2|A0A7P0T8N2_HUMAN,tr|A0A7P0T9C4|A0A7P0T9C4_HUMAN,tr|A0A7P0TBJ7|A0A7P0TBJ7_HUMAN,tr|A0A7P0T9K2|A0A7P0T9K2_HUMAN,tr|A0A2R8Y706|A0A2R8Y706_HUMAN,tr|A0A7P0T916|A0A7P0T916_HUMAN,tr|A0A7P0TB75|A0A7P0TB75_HUMAN,tr|A0A7P0T8W5|A0A7P0T8W5_HUMAN,tr|A0A7P0TAF3|A0A7P0TAF3_HUMAN,tr|A0A7P0T9F1|A0A7P0T9F1_HUMAN,tr|A0A7P0TAW9|A0A7P0TAW9_HUMAN,tr|A0A7P0TA13|A0A7P0TA13_HUMAN,tr|A0A7P0T7V5|A0A7P0T7V5_HUMAN,tr|A0A7P0T9R4|A0A7P0T9R4_HUMAN,tr|A0A2R8Y5T0|A0A2R8Y5T0_HUMAN,tr|A0A2R8YFZ7|A0A2R8YFZ7_HUMAN,tr|A0A2R8Y6H2|A0A2R8Y6H2_HUMAN" 18 1196.5309 0.92 61617 8929 2 1196.530046 599.2727 Cytoplasmic dynein 1 heavy chain 1 OS=Homo sapiens OX=9606 GN=DYNC1H1 PE=1 SV=5 4.14 1981.8 - 833985 - - - -0.7522 - 2.217 0.546 - 429.5 1 2 0 -0.0009 10 0 0 0 1.89E+07 2.07E+07 - - - 5.2958 0.9778 221125_WJC_METTL3_EV_vs_WT_F05.08932.08932.2 3.00E-05 16-Sep K.K[136.11]QQISLATQ.M "sp|P48643|TCPE_HUMAN,tr|E9PCA1|E9PCA1_HUMAN,tr|B7ZAR1|B7ZAR1_HUMAN,tr|E7ENZ3|E7ENZ3_HUMAN" 4 1023.5804 0.54 61620 8932 2 1023.581366 512.7975 T-complex protein 1 subunit epsilon OS=Homo sapiens OX=9606 GN=CCT5 PE=1 SV=1 8.75 1982.2 - 353871 - - - 0.935 - 1.713 0.406 - 313.1 1 1 0 0.001 9 0 0 0 1.20E+07 2.23E+07 - - - 3.5966 0.9999 221125_WJC_METTL3_EV_vs_WT_F05.08940.08940.2 0.00168 14/28 R.FGQGGAGPVGGQGPR.G sp|P23246|SFPQ_HUMAN 1 1340.6585 0.87 61626 8940 2 1340.660179 671.3365 "Splicing factor, proline- and glutamine-rich OS=Homo sapiens OX=9606 GN=SFPQ PE=1 SV=2" 9.75 1983.3 - 2.08E+06 - - - 1.2181 - 2.824 0.528 - 595.3 1 2 0 0.0016 15 0 0 0 3.20E+08 3.68E+08 - - - 5.4926 0.88 221125_WJC_METTL3_EV_vs_WT_F05.08943.08943.3 1.51 Aug-32 K.VFC[160.03]VQRPDR.- "sp|Q13685|AAMP_HUMAN,tr|H7C0R2|H7C0R2_HUMAN,tr|C9JG97|C9JG97_HUMAN,tr|C9JEH3|C9JEH3_HUMAN" 4 1175.587 0.77 61629 8943 3 1175.588135 392.8696 Angio-associated migratory cell protein OS=Homo sapiens OX=9606 GN=AAMP PE=1 SV=2 8.22 1983.5 - 906870 - - - 0.9978 - 1.267 0.102 - 94.1 1 2 0 0.0012 9 0 0 0 2.78E+07 3.60E+07 - - - 0.3901 1 221125_WJC_METTL3_EV_vs_WT_F05.08945.08945.2 5.68E-10 14/26 K.ATSSATTAAAPTLR[166.11].R "sp|Q8N9M1|CS047_HUMAN,tr|J3QS80|J3QS80_HUMAN,tr|A0A2R8Y6U9|A0A2R8Y6U9_HUMAN,tr|A0A804HLH2|A0A804HLH2_HUMAN" 4 1327.6971 1.1 61631 8945 2 1327.69675 664.8558 Uncharacterized protein C19orf47 OS=Homo sapiens OX=9606 GN=C19orf47 PE=1 SV=1 9.79 1983.8 - 782648 - - - -0.2742 - 3.088 0.596 - 899.1 1 2 0 -0.0004 14 0 0 0 1.66E+07 1.51E+07 - - - 6.2724 0.9972 221125_WJC_METTL3_EV_vs_WT_F05.08948.08948.2 0.0894 18-Aug K.LQAEISQAAR.K sp|O43395|PRPF3_HUMAN 1 1085.5829 2.38 61634 8948 2 1085.583366 543.7987 U4\U6 small nuclear ribonucleoprotein Prp3 OS=Homo sapiens OX=9606 GN=PRPF3 PE=1 SV=2 6 1984.1 - 621877 - - - 0.409 - 1.443 0.203 - 209.6 1 2 0 0.0004 10 0 0 0 7.03E+06 2.95E+06 - - - 1.5639 0.9985 221125_WJC_METTL3_EV_vs_WT_F05.08949.08949.2 0.0181 16-Sep R.EEEIEVDSR[166.11].V "sp|Q14978|NOLC1_HUMAN,tr|A0A0A0MRM9|A0A0A0MRM9_HUMAN" 2 1114.5018 2.14 61635 8949 2 1114.504168 558.2582 Nucleolar and coiled-body phosphoprotein 1 OS=Homo sapiens OX=9606 GN=NOLC1 PE=1 SV=2 3.91 1984.2 - 314362 - - - 2.1534 - 1.723 0.309 - 348 1 2 0 0.0024 9 0 0 0 4.49E+07 2.09E+07 - - - 2.8965 0.9997 221125_WJC_METTL3_EV_vs_WT_F05.08955.08955.2 0.000534 16-Oct R.EEEIEVDSR.V "sp|Q14978|NOLC1_HUMAN,tr|A0A0A0MRM9|A0A0A0MRM9_HUMAN" 2 1104.4935 2.07 61640 8955 2 1104.494963 553.254 Nucleolar and coiled-body phosphoprotein 1 OS=Homo sapiens OX=9606 GN=NOLC1 PE=1 SV=2 3.91 1984.8 - 1.32E+06 - - - 1.3264 - 1.961 0.451 - 489.7 1 2 0 0.0015 9 0 0 0 4.50E+07 2.17E+07 - - - 4.32 0.9968 221125_WJC_METTL3_EV_vs_WT_F05.08956.08956.3 0.0471 Jul-44 R.VVDDDGMTSLHK.A sp|Q53RE8|ANR39_HUMAN 1 1315.6078 3.99 61641 8956 3 1315.610865 439.5432 Ankyrin repeat domain-containing protein 39 OS=Homo sapiens OX=9606 GN=ANKRD39 PE=1 SV=1 4.41 1985 - 305881 - - - 2.3176 - 1.576 0.296 - 39.6 1 2 0 0.003 12 0 0 0 9.68E+06 2.43E+06 - - - 3.1001 0.9998 221125_WJC_METTL3_EV_vs_WT_F05.08959.08959.2 0.000526 18-Oct K.SVEVEGYGSK.K "sp|Q7L2E3|DHX30_HUMAN,tr|H7BXY3|H7BXY3_HUMAN" 2 1053.4979 0.6 61643 8959 2 1053.499336 527.7562 ATP-dependent RNA helicase DHX30 OS=Homo sapiens OX=9606 GN=DHX30 PE=1 SV=1 4.53 1985.4 - 1.39E+06 - - - 1.4058 - 1.958 0.53 - 274.9 1 2 0 0.0015 10 0 0 0 1.55E+07 2.58E+07 - - - 4.8307 0.9378 221125_WJC_METTL3_EV_vs_WT_F05.08962.08962.3 0.00671 Oct-36 K.MADHWETAPR.H "sp|P49750|YLPM1_HUMAN,tr|U3KQT9|U3KQT9_HUMAN,tr|H0YIQ2|H0YIQ2_HUMAN,tr|F8VU51|F8VU51_HUMAN,tr|H0YI23|H0YI23_HUMAN" 5 1212.5346 1.2 61645 8962 3 1212.536921 405.1855 YLP motif-containing protein 1 OS=Homo sapiens OX=9606 GN=YLPM1 PE=1 SV=4 5.3 1985.7 - 527693 - - - 1.9216 - 1.272 0.164 - 107.9 1 2 0 0.0023 10 0 0 0 8.17E+06 6.79E+06 - - - 1.0704 0.9996 221125_WJC_METTL3_EV_vs_WT_F05.08964.08964.2 9.63E-10 24-Dec K.VIEC[160.03]SYTSADGQR.H "sp|Q9UBM7|DHCR7_HUMAN,tr|A0A804HI25|A0A804HI25_HUMAN,tr|A0A804HJQ7|A0A804HJQ7_HUMAN,tr|H0YE57|H0YE57_HUMAN" 4 1484.6566 0.88 61647 8964 2 1484.651812 743.3356 7-dehydrocholesterol reductase OS=Homo sapiens OX=9606 GN=DHCR7 PE=1 SV=1 4.37 1986 - 384036 - - - -3.196 - 2.315 0.61 - 525.7 1 2 0 -0.0047 13 0 0 0 5.58E+06 6.37E+06 - - - 5.6993 0.9955 221125_WJC_METTL3_EV_vs_WT_F05.08965.08965.3 0.00304 Oct-40 R.VASSTLLDDRR.N sp|O60763|USO1_HUMAN 1 1231.6521 2 61648 8965 3 1231.655752 411.558 General vesicular transport factor p115 OS=Homo sapiens OX=9606 GN=USO1 PE=1 SV=2 5.93 1986.1 - 379033 - - - 2.9944 - 2.025 0.238 - 118.7 1 2 0 0.0037 11 0 0 0 7.05E+07 3.53E+07 - - - 3.1968 0.9993 221125_WJC_METTL3_EV_vs_WT_F05.08971.08971.2 3.37E-05 20-Sep K.SEQPTLVTASK[136.11].D sp|Q8IWA0|WDR75_HUMAN 1 1167.6227 1.5 61652 8971 2 1167.625898 584.8186 WD repeat-containing protein 75 OS=Homo sapiens OX=9606 GN=WDR75 PE=1 SV=1 5.72 1986.9 - 801720 - - - 2.7663 - 1.864 0.486 - 271.1 1 2 0 0.0032 11 0 0 0 2.33E+07 1.55E+07 - - - 4.3142 0.9996 221125_WJC_METTL3_EV_vs_WT_F05.08972.08972.2 0.0171 16-Nov R.QGANINEIR.Q sp|Q15365|PCBP1_HUMAN 1 1013.5254 0.83 61653 8972 2 1013.526812 507.77 Poly(rC)-binding protein 1 OS=Homo sapiens OX=9606 GN=PCBP1 PE=1 SV=2 6 1987 - 1.07E+06 - - - 1.3863 - 2.342 0.297 - 634.2 1 2 0 0.0014 9 0 0 0 2.39E+07 2.87E+07 - - - 3.6962 0.9998 221125_WJC_METTL3_EV_vs_WT_F05.08976.08976.2 0.000178 18-Oct R.QAANLQDC[160.03]YR[166.11].L "sp|P43246|MSH2_HUMAN,tr|A0A2R8YG02|A0A2R8YG02_HUMAN,tr|A0A2R8Y7S8|A0A2R8Y7S8_HUMAN,tr|E9PHA6|E9PHA6_HUMAN,tr|A0A2R8YFH0|A0A2R8YFH0_HUMAN,tr|A0A2R8Y6P0|A0A2R8Y6P0_HUMAN" 6 1247.5592 0.25 61657 8976 2 1247.561352 624.7869 DNA mismatch repair protein Msh2 OS=Homo sapiens OX=9606 GN=MSH2 PE=1 SV=1 5.83 1987.5 - 294365 - - - 1.6929 - 2.223 0.59 - 477.5 1 2 0 0.0021 10 0 0 0 7.23E+06 2.86E+07 - - - 5.6279 0.9992 221125_WJC_METTL3_EV_vs_WT_F05.08978.08978.2 0.0016 18-Jun R.QAANLQDC[160.03]YR.L "sp|P43246|MSH2_HUMAN,tr|A0A2R8YG02|A0A2R8YG02_HUMAN,tr|A0A2R8Y7S8|A0A2R8Y7S8_HUMAN,tr|E9PHA6|E9PHA6_HUMAN,tr|A0A2R8YFH0|A0A2R8YFH0_HUMAN,tr|A0A2R8Y6P0|A0A2R8Y6P0_HUMAN" 6 1237.551 0.85 61659 8978 2 1237.551363 619.7828 DNA mismatch repair protein Msh2 OS=Homo sapiens OX=9606 GN=MSH2 PE=1 SV=1 5.83 1987.7 - 149399 - - - 0.3176 - 1.483 0.328 - 119.5 1 2 0 0.0004 10 0 0 0 6.36E+06 7.48E+06 - - - 2.5634 0.9989 221125_WJC_METTL3_EV_vs_WT_F05.08981.08981.2 0.0222 16-Aug R.QGANINEIR[166.11].Q sp|Q15365|PCBP1_HUMAN 1 1023.5337 0.83 61660 8981 2 1023.534087 512.7741 Poly(rC)-binding protein 1 OS=Homo sapiens OX=9606 GN=PCBP1 PE=1 SV=2 6 1988.1 - 1.85E+06 - - - 0.4006 - 1.734 0.227 - 289.8 1 2 0 0.0004 9 0 0 0 2.39E+07 2.87E+07 - - - 2.3099 1 221125_WJC_METTL3_EV_vs_WT_F05.08983.08983.3 0.000414 14/44 R.FVTPSEPVAHSR[166.11].R "sp|O14654|IRS4_HUMAN,tr|A0A804CF45|A0A804CF45_HUMAN" 2 1335.6811 0.8 61662 8983 3 1335.681123 446.2343 Insulin receptor substrate 4 OS=Homo sapiens OX=9606 GN=IRS4 PE=1 SV=1 6.75 1988.3 - 1.31E+06 - - - 0.0397 - 2.263 0.474 - 242.8 1 2 0 0.0001 12 0 0 0 1.04E+08 1.29E+08 - - - 6.0884 0.9999 221125_WJC_METTL3_EV_vs_WT_F05.08984.08984.3 0.00021 14/56 R.FGQGGAGPVGGQGPR[166.11].G sp|P23246|SFPQ_HUMAN 1 1350.6668 0.7 61663 8984 3 1350.667917 451.2295 "Splicing factor, proline- and glutamine-rich OS=Homo sapiens OX=9606 GN=SFPQ PE=1 SV=2" 9.75 1988.4 - 942634 - - - 0.8152 - 2.388 0.453 - 177.8 1 2 0 0.0011 15 0 0 0 9.45E+06 1.34E+07 - - - 5.8615 0.9993 221125_WJC_METTL3_EV_vs_WT_F05.08986.08986.3 0.0149 15/32 R.LYDLDKDEK.L "sp|Q99653|CHP1_HUMAN,tr|H0YLY7|H0YLY7_HUMAN,tr|H0YNG9|H0YNG9_HUMAN" 3 1137.5554 0.7 61665 8986 3 1137.55442 380.1924 Calcineurin B homologous protein 1 OS=Homo sapiens OX=9606 GN=CHP1 PE=1 SV=3 4.23 1988.6 - 823286 - - - -0.8351 - 2.323 0.332 - 245.9 1 2 1 -0.0009 9 0 0 0 9.68E+06 1.38E+07 - - - 4.7814 0.9974 221125_WJC_METTL3_EV_vs_WT_F05.08987.08987.2 0.006 18-Oct R.VNNVYDVDNK[136.11].T "sp|O60524|NEMF_HUMAN,tr|G3V547|G3V547_HUMAN,tr|G3V5V3|G3V5V3_HUMAN,tr|G3V4D9|G3V4D9_HUMAN" 4 1186.571 7.22 61666 8987 2 1186.57556 594.2928 Nuclear export mediator factor NEMF OS=Homo sapiens OX=9606 GN=NEMF PE=1 SV=4 4.21 1988.7 - 419086 - - - 3.8708 - 1.809 0.388 - 402.5 1 2 0 0.0046 10 0 0 0 3.22E+07 4.46E+06 - - - 3.5599 1 221125_WJC_METTL3_EV_vs_WT_F05.08988.08988.2 3.69E-07 13/22 K.AEGEPQEESPLK.S "sp|Q9NYF8|BCLF1_HUMAN,tr|E9PKI6|E9PKI6_HUMAN,tr|A0A1W2PQ43|A0A1W2PQ43_HUMAN,tr|E9PK91|E9PK91_HUMAN,tr|E9PJA7|E9PJA7_HUMAN,tr|E9PK09|E9PK09_HUMAN,tr|E9PQN2|E9PQN2_HUMAN" 7 1312.6147 2.77 61667 8988 2 1312.615371 657.3146 Bcl-2-associated transcription factor 1 OS=Homo sapiens OX=9606 GN=BCLAF1 PE=1 SV=2 4.09 1988.9 - 398376 - - - 0.5295 - 2.449 0.602 - 668.2 1 2 0 0.0007 12 0 0 0 9.75E+07 3.53E+07 - - - 5.8438 0.9584 221125_WJC_METTL3_EV_vs_WT_F05.08989.08989.2 0.0197 20-Oct R.VSPPPAPSPPK[136.11].A "sp|O14654|IRS4_HUMAN,tr|A0A804CF45|A0A804CF45_HUMAN" 2 1080.6059 1.67 61668 8989 2 1080.610062 541.3102 Insulin receptor substrate 4 OS=Homo sapiens OX=9606 GN=IRS4 PE=1 SV=1 8.72 1989 - 328472 - - - 3.8552 - 1.679 0.089 - 250.7 1 2 0 0.0042 11 0 0 0 1.01E+07 6.04E+06 - - - 1.0989 0.9997 221125_WJC_METTL3_EV_vs_WT_F05.08992.08992.2 0.0082 18-Oct K.SVEVEGYGSK[136.11].K "sp|Q7L2E3|DHX30_HUMAN,tr|H7BXY3|H7BXY3_HUMAN" 2 1061.5121 0.65 61670 8992 2 1061.513103 531.7633 ATP-dependent RNA helicase DHX30 OS=Homo sapiens OX=9606 GN=DHX30 PE=1 SV=1 4.53 1989.4 - 426197 - - - 0.9873 - 1.819 0.418 - 225.9 1 2 0 0.001 10 0 0 0 1.56E+07 2.41E+07 - - - 3.798 0.9998 221125_WJC_METTL3_EV_vs_WT_F05.08994.08994.2 0.000902 16-Sep K.AQYEEIAQR.S "sp|P48668|K2C6C_HUMAN,sp|Q01546|K22O_HUMAN,sp|P19013|K2C4_HUMAN,sp|P04259|K2C6B_HUMAN,sp|P35908|K22E_HUMAN,sp|P02538|K2C6A_HUMAN" 6 1106.5356 5280.68 61672 8994 2 1106.536093 554.2751 "Keratin, type II cytoskeletal 6C OS=Homo sapiens OX=9606 GN=KRT6C PE=1 SV=3" 4.53 1989.5 - 9.62E+06 - - - 0.4121 - 1.901 0.42 - 467.2 1 2 0 0.0005 9 0 0 0 1.35E+10 2.55E+06 - - - 4.0014 0.996 221125_WJC_METTL3_EV_vs_WT_F05.08995.08995.2 0.0193 20-Sep K.EPPSSPLQPQK[136.11].E "sp|Q92615|LAR4B_HUMAN,tr|A0A087X183|A0A087X183_HUMAN,tr|H0Y4V9|H0Y4V9_HUMAN" 3 1214.6387 2.07 61673 8995 2 1214.640572 608.3266 La-related protein 4B OS=Homo sapiens OX=9606 GN=LARP4B PE=1 SV=3 6.1 1989.6 - 1.35E+06 - - - 1.5807 - 1.498 0.213 - 262.1 1 2 0 0.0019 11 0 0 0 1.74E+08 8.39E+07 - - - 1.7069 0.9284 221125_WJC_METTL3_EV_vs_WT_F05.08996.08996.3 0.362 Dec-44 R.FVTPSEPVAHSR.R "sp|O14654|IRS4_HUMAN,tr|A0A804CF45|A0A804CF45_HUMAN" 2 1325.6728 0.81 61674 8996 3 1325.671495 442.8982 Insulin receptor substrate 4 OS=Homo sapiens OX=9606 GN=IRS4 PE=1 SV=1 6.75 1989.7 - 1.23E+06 - - - -0.9844 - 1.659 0.063 - 165.1 1 2 0 -0.0013 12 0 0 0 1.04E+08 1.29E+08 - - - 0.6452 1 221125_WJC_METTL3_EV_vs_WT_F05.08998.08998.3 2.89E-05 15/56 R.FGQGGAGPVGGQGPR.G sp|P23246|SFPQ_HUMAN 1 1340.6585 0.7 61676 8998 3 1340.658601 447.8935 "Splicing factor, proline- and glutamine-rich OS=Homo sapiens OX=9606 GN=SFPQ PE=1 SV=2" 9.75 1989.9 - 848626 - - - 0.041 - 2.385 0.488 - 221.1 1 2 0 0.0001 15 0 0 0 9.45E+06 1.34E+07 - - - 6.2488 0.9599 221125_WJC_METTL3_EV_vs_WT_F05.09000.09000.2 0.176 14-Jul K.GFEDKLDR.G sp|Q5VT06|CE350_HUMAN 1 978.4771 0.63 61678 9000 2 978.476391 490.2458 Centrosome-associated protein 350 OS=Homo sapiens OX=9606 GN=CEP350 PE=1 SV=1 4.56 1990.1 - 588932 - - - -0.6837 - 1.413 0.174 - 224.3 1 2 1 -0.0007 8 0 0 0 5.80E+06 9.14E+06 - - - 1.3686 0.9997 221125_WJC_METTL3_EV_vs_WT_F05.09005.09005.2 0.0181 18-Sep R.EIQQELSSGR.N "sp|P18583|SON_HUMAN,tr|J3QSZ5|J3QSZ5_HUMAN" 2 1145.5677 2.6 61681 9005 2 1145.568253 573.7911 Protein SON OS=Homo sapiens OX=9606 GN=SON PE=1 SV=4 4.53 1990.7 - 5.40E+06 - - - 0.5124 - 1.763 0.395 - 412.2 1 2 0 0.0006 10 0 0 0 1.11E+08 4.27E+07 - - - 3.541 0.9999 221125_WJC_METTL3_EV_vs_WT_F05.09006.09006.2 1.63E-06 14/26 K.GLGTGQGAVSGPPR.K "sp|O00255|MEN1_HUMAN,tr|A0A5F9ZHS3|A0A5F9ZHS3_HUMAN,tr|E7EN32|E7EN32_HUMAN" 3 1252.6524 1.55 61682 9006 2 1252.651368 627.3335 Menin OS=Homo sapiens OX=9606 GN=MEN1 PE=1 SV=4 9.75 1990.8 - 903776 - - - -0.8223 - 2.886 0.512 - 695.9 1 2 0 -0.001 14 0 0 0 1.04E+07 6.71E+06 - - - 5.482 0.9996 221125_WJC_METTL3_EV_vs_WT_F05.09007.09007.2 0.000188 16-Sep R.QQQLNDVVK[136.11].N sp|P38432|COIL_HUMAN 1 1078.5862 1.05 61683 9007 2 1078.585677 540.3004 Coilin OS=Homo sapiens OX=9606 GN=COIL PE=1 SV=1 5.84 1990.9 - 692643 - - - -0.5062 - 1.848 0.35 - 366.4 1 2 0 -0.0005 9 0 0 0 4.99E+07 4.77E+07 - - - 3.4026 1 221125_WJC_METTL3_EV_vs_WT_F05.09010.09010.2 6.74E-09 13/26 K.EEPVSSGPEEAVGK[136.11].S sp|O00567|NOP56_HUMAN 1 1421.6766 1.06 61686 9010 2 1421.676783 711.8456 Nucleolar protein 56 OS=Homo sapiens OX=9606 GN=NOP56 PE=1 SV=4 4.09 1991.3 - 165670 - - - 0.1611 - 2.642 0.656 - 437.5 1 2 0 0.0002 14 0 0 0 8.73E+06 8.23E+06 - - - 6.3242 0.9993 221125_WJC_METTL3_EV_vs_WT_F05.09013.09013.3 5.92E-05 Oct-40 K.VDK[136.11]LDASESLR[166.11].K "sp|Q00610|CLH1_HUMAN,tr|K7EJJ5|K7EJJ5_HUMAN,tr|J3KS13|J3KS13_HUMAN,tr|A0A087WVQ6|A0A087WVQ6_HUMAN" 4 1249.6633 0.95 61687 9013 3 1249.660798 417.5617 Clathrin heavy chain 1 OS=Homo sapiens OX=9606 GN=CLTC PE=1 SV=5 4.56 1991.7 - 1.59E+06 - - - -2.0029 - 2.319 0.395 - 198.5 1 2 1 -0.0025 11 0 0 0 7.17E+07 7.54E+07 - - - 5.3327 0.9471 221125_WJC_METTL3_EV_vs_WT_F05.09015.09015.2 0.062 26-Jul R.GGGGGGYGSGGSSY.G sp|P04264|K2C1_HUMAN 1 1118.4265 - 61689 9015 2 1118.427145 560.2205 "Keratin, type II cytoskeletal 1 OS=Homo sapiens OX=9606 GN=KRT1 PE=1 SV=6" 5.52 1992 - 941351 - - - 0.5937 - 1.134 0.431 - 105.6 1 1 0 0.0007 14 0 0 0 - - - - - 2.5397 0.9935 221125_WJC_METTL3_EV_vs_WT_F05.09016.09016.3 0.00624 Sep-36 R.IVEYEK[136.11]EMEK[136.11].M sp|O75947|ATP5H_HUMAN 1 1312.6556 1.38 61690 9016 3 1312.659632 438.5591 "ATP synthase subunit d, mitochondrial OS=Homo sapiens OX=9606 GN=ATP5PD PE=1 SV=3" 4.49 1992.1 - 807915 - - - 3.1059 - 2.067 0.31 - 131.9 1 2 1 0.0041 10 0 0 0 4.39E+07 3.18E+07 - - - 4.1156 0.981 221125_WJC_METTL3_EV_vs_WT_F05.09017.09017.2 2.93E-06 22-Dec K.AEGEPQEESPLK[136.11].S "sp|Q9NYF8|BCLF1_HUMAN,tr|E9PKI6|E9PKI6_HUMAN,tr|A0A1W2PQ43|A0A1W2PQ43_HUMAN,tr|E9PK91|E9PK91_HUMAN,tr|E9PJA7|E9PJA7_HUMAN,tr|E9PK09|E9PK09_HUMAN,tr|E9PQN2|E9PQN2_HUMAN" 7 1320.6289 2.75 61691 9017 2 1320.616927 661.3217 Bcl-2-associated transcription factor 1 OS=Homo sapiens OX=9606 GN=BCLAF1 PE=1 SV=2 4.09 1992.2 - 513423 - - - -9.048 - 2.015 0.543 - 268 1 2 0 -0.0119 12 0 0 0 9.88E+07 3.59E+07 - - - 4.8913 1 221125_WJC_METTL3_EV_vs_WT_F05.09021.09021.2 3.12E-08 14/24 R.EVATNSELVQSGK.S "sp|Q04695|K1C17_HUMAN,sp|P02533|K1C14_HUMAN,tr|K7ESE1|K7ESE1_HUMAN,tr|F5GWP8|F5GWP8_HUMAN" 4 1360.6834 999 61693 9021 2 1360.679195 681.349 "Keratin, type I cytoskeletal 17 OS=Homo sapiens OX=9606 GN=KRT17 PE=1 SV=2" 4.53 1992.8 - 846622 - - - -3.108 - 2.727 0.623 - 703.1 1 2 0 -0.0042 13 0 0 0 2.06E+07 0.00E+00 - - - 6.2159 0.9997 221125_WJC_METTL3_EV_vs_WT_F05.09022.09022.2 1.09E-05 20-Oct K.GESPVDYDGGR.T sp|Q15084|PDIA6_HUMAN 1 1150.4891 1.17 61694 9022 2 1150.487643 576.2518 Protein disulfide-isomerase A6 OS=Homo sapiens OX=9606 GN=PDIA6 PE=1 SV=1 4.03 1992.9 - 978263 - - - -1.2499 - 2.016 0.43 - 461.2 1 2 0 -0.0014 11 0 0 0 9.56E+07 8.18E+07 - - - 4.1132 0.8845 221125_WJC_METTL3_EV_vs_WT_F05.09025.09025.2 0.751 18-Jul K.YQINQNGEVR[166.11].L "sp|Q8IZH2|XRN1_HUMAN,tr|H7C5E4|H7C5E4_HUMAN" 2 1229.6028 1.63 61695 9025 2 1229.599311 615.8087 5'-3' exoribonuclease 1 OS=Homo sapiens OX=9606 GN=XRN1 PE=1 SV=1 6 1993.3 - 1.11E+06 - - - -2.853 - 1.076 0.126 - 34.3 5 2 0 -0.0035 10 0 0 0 2.50E+07 1.53E+07 - - - -0.1372 0.9989 221125_WJC_METTL3_EV_vs_WT_F05.09026.09026.2 0.00108 20-Oct R.LVSSDPEINTK.K sp|Q9Y266|NUDC_HUMAN 1 1201.619 0.49 61696 9026 2 1201.622492 601.8168 Nuclear migration protein nudC OS=Homo sapiens OX=9606 GN=NUDC PE=1 SV=1 4.37 1993.4 - 723152 - - - 2.8786 - 1.814 0.421 - 272.5 1 2 0 0.0035 11 0 0 0 1.77E+07 3.58E+07 - - - 3.7605 0.92 221125_WJC_METTL3_EV_vs_WT_F05.09029.09029.2 0.00983 14-Sep A.QYEEIAQR.S "sp|P48668|K2C6C_HUMAN,sp|Q01546|K22O_HUMAN,sp|P19013|K2C4_HUMAN,sp|P04259|K2C6B_HUMAN,sp|P35908|K22E_HUMAN,sp|P02538|K2C6A_HUMAN" 6 1035.4985 3.05 61699 9029 2 1035.496434 518.7565 "Keratin, type II cytoskeletal 6C OS=Homo sapiens OX=9606 GN=KRT6C PE=1 SV=3" 4.53 1993.8 - 713214 - - - -2.0174 - 1.592 0.312 - 471 1 1 0 -0.0021 8 0 0 0 3.18E+07 1.04E+07 - - - 2.7472 0.9872 221125_WJC_METTL3_EV_vs_WT_F05.09030.09030.2 0.0128 16-Aug K.SNQIPTEVR[166.11].S sp|Q9BWH2|FUND2_HUMAN 1 1052.549 324.51 61700 9030 2 1052.543439 527.2818 FUN14 domain-containing protein 2 OS=Homo sapiens OX=9606 GN=FUNDC2 PE=1 SV=2 5.72 1993.9 - 576773 - - - -5.2767 - 1.834 0.288 - 262.3 1 2 0 -0.0056 9 0 0 0 2.26E+09 6.97E+06 - - - 2.9211 0.9978 221125_WJC_METTL3_EV_vs_WT_F05.09031.09031.2 0.0226 14-Sep K.TQLEINGR[166.11].N "sp|Q9NR56|MBNL1_HUMAN,sp|Q5VZF2|MBNL2_HUMAN,sp|Q9NUK0|MBNL3_HUMAN,tr|H7C4T5|H7C4T5_HUMAN,tr|Q86VM6|Q86VM6_HUMAN,tr|C9J4T8|C9J4T8_HUMAN,tr|A0A0A0MQX8|A0A0A0MQX8_HUMAN,tr|A0A7P0T9I3|A0A7P0T9I3_HUMAN,tr|B1AKI6|B1AKI6_HUMAN,tr|C9JP00|C9JP00_HUMAN,tr|O95205|O95205_HUMAN" 11 939.5013 1.48 61701 9031 2 939.499209 470.7579 Muscleblind-like protein 1 OS=Homo sapiens OX=9606 GN=MBNL1 PE=1 SV=2 5.66 1994.1 - 536245 - - - -2.2406 - 1.76 0.237 - 389.4 1 2 0 -0.0021 8 0 0 0 4.65E+07 3.15E+07 - - - 2.4958 0.8568 221125_WJC_METTL3_EV_vs_WT_F05.09034.09034.2 0.197 18-Jul R.IVEYEKEMEK.M sp|O75947|ATP5H_HUMAN 1 1296.6272 3.94 61704 9034 2 1296.629217 649.3209 "ATP synthase subunit d, mitochondrial OS=Homo sapiens OX=9606 GN=ATP5PD PE=1 SV=3" 4.49 1994.4 - 211279 - - - 1.5903 - 1.101 0.196 - 108.5 1 2 1 0.0021 10 0 0 0 2.94E+06 7.46E+05 - - - 0.7566 0.9935 221125_WJC_METTL3_EV_vs_WT_F05.09038.09038.3 0.00796 13/40 R.EAANLLEGHAR[166.11].A "sp|O00461|GOLI4_HUMAN,tr|F8W785|F8W785_HUMAN" 2 1189.6079 1.48 61706 9038 3 1189.604181 397.5432 Golgi integral membrane protein 4 OS=Homo sapiens OX=9606 GN=GOLIM4 PE=1 SV=1 5.4 1995 - 963535 - - - -3.1304 - 2.428 0.173 - 257 1 2 0 -0.0037 11 0 0 0 8.07E+07 5.46E+07 - - - 2.9878 0.9999 221125_WJC_METTL3_EV_vs_WT_F05.09039.09039.2 7.26E-06 18-Nov R.NNSVSGLSVK.S "sp|Q9UHI6|DDX20_HUMAN,tr|A0A7P0T9T8|A0A7P0T9T8_HUMAN" 2 1003.5298 1.12 61707 9039 2 1003.529423 502.7722 Probable ATP-dependent RNA helicase DDX20 OS=Homo sapiens OX=9606 GN=DDX20 PE=1 SV=2 8.75 1995.1 - 2.41E+06 - - - -0.3996 - 2.165 0.482 - 632.3 1 2 0 -0.0004 10 0 0 0 3.56E+07 3.19E+07 - - - 4.757 0.9998 221125_WJC_METTL3_EV_vs_WT_F05.09042.09042.3 0.000544 Dec-40 K.EAIEGTYIDK[136.11]K[136.11].C "sp|P62280|RS11_HUMAN,tr|M0QZC5|M0QZC5_HUMAN" 2 1281.6787 0.97 61710 9042 3 1281.681337 428.2335 40S ribosomal protein S11 OS=Homo sapiens OX=9606 GN=RPS11 PE=1 SV=3 4.68 1995.4 - 573635 - - - 2.0317 - 1.957 0.445 - 220.4 1 2 0 0.0026 11 0 0 0 1.18E+08 1.22E+08 - - - 5.408 0.9906 221125_WJC_METTL3_EV_vs_WT_F05.09043.09043.2 0.00975 18-Aug R.KVPVPIGTER.S "sp|O75179|ANR17_HUMAN,tr|H0YM23|H0YM23_HUMAN" 2 1094.6448 3.84 61711 9043 2 1094.640249 548.3297 Ankyrin repeat domain-containing protein 17 OS=Homo sapiens OX=9606 GN=ANKRD17 PE=1 SV=3 8.75 1995.5 - 550522 - - - -4.152 - 1.396 0.337 - 208.3 1 2 0 -0.0045 10 0 0 0 1.78E+07 4.63E+06 - - - 2.4599 1 221125_WJC_METTL3_EV_vs_WT_F05.09044.09044.2 5.34E-09 18/28 R.PVAPSGTALSTTSSK.L "sp|P35658|NU214_HUMAN,tr|A0A0A0MSW3|A0A0A0MSW3_HUMAN,tr|E9PKD2|E9PKD2_HUMAN,tr|B7ZAV2|B7ZAV2_HUMAN,tr|A0A494C1F2|A0A494C1F2_HUMAN,tr|H0Y837|H0Y837_HUMAN" 6 1402.7304 2.24 61712 9044 2 1402.725307 702.3725 Nuclear pore complex protein Nup214 OS=Homo sapiens OX=9606 GN=NUP214 PE=1 SV=2 9.18 1995.7 - 528749 - - - -3.6122 - 3.138 0.619 - 919.8 1 1 0 -0.0051 15 0 0 0 6.02E+07 2.69E+07 - - - 6.4229 0.997 221125_WJC_METTL3_EV_vs_WT_F05.09047.09047.3 0.0001 13/40 R.EAANLLEGHAR.A "sp|O00461|GOLI4_HUMAN,tr|F8W785|F8W785_HUMAN" 2 1179.5996 1.46 61713 9047 3 1179.596644 394.2072 Golgi integral membrane protein 4 OS=Homo sapiens OX=9606 GN=GOLIM4 PE=1 SV=1 5.4 1996.1 - 1.79E+06 - - - -2.5356 - 2.35 0.203 - 290.9 1 2 0 -0.003 11 0 0 0 8.07E+07 5.53E+07 - - - 3.2297 0.999 221125_WJC_METTL3_EV_vs_WT_F05.09049.09049.2 0.0209 14-Aug K.TQLEINGR.N "sp|Q9NR56|MBNL1_HUMAN,sp|Q5VZF2|MBNL2_HUMAN,sp|Q9NUK0|MBNL3_HUMAN,tr|H7C4T5|H7C4T5_HUMAN,tr|Q86VM6|Q86VM6_HUMAN,tr|C9J4T8|C9J4T8_HUMAN,tr|A0A0A0MQX8|A0A0A0MQX8_HUMAN,tr|A0A7P0T9I3|A0A7P0T9I3_HUMAN,tr|B1AKI6|B1AKI6_HUMAN,tr|C9JP00|C9JP00_HUMAN,tr|O95205|O95205_HUMAN" 11 929.493 1.48 61714 9049 2 929.491871 465.7538 Muscleblind-like protein 1 OS=Homo sapiens OX=9606 GN=MBNL1 PE=1 SV=2 5.66 1996.3 - 2.14E+06 - - - -1.262 - 1.625 0.286 - 338.8 1 2 0 -0.0012 8 0 0 0 4.65E+07 3.15E+07 - - - 2.6173 1 221125_WJC_METTL3_EV_vs_WT_F05.09051.09051.3 4.94E-06 14/48 R.LAQGHTTVDELAR[166.11].R "sp|Q15149|PLEC_HUMAN,tr|H0YDN1|H0YDN1_HUMAN" 2 1419.7346 8.69 61715 9051 3 1419.734306 474.2521 Plectin OS=Homo sapiens OX=9606 GN=PLEC PE=1 SV=3 5.32 1996.5 - 1.24E+06 - - - -0.1803 - 2.674 0.422 - 430.2 1 2 0 -0.0003 13 0 0 0 6.10E+08 7.02E+07 - - - 5.9116 0.9907 221125_WJC_METTL3_EV_vs_WT_F05.09052.09052.2 0.00498 18-Sep K.ASPFEEDQNR.D "sp|Q8TB72|PUM2_HUMAN,tr|A0A0C4DG68|A0A0C4DG68_HUMAN,tr|C9JW01|C9JW01_HUMAN" 3 1191.5156 1.58 61716 9052 2 1191.510981 596.7651 Pumilio homolog 2 OS=Homo sapiens OX=9606 GN=PUM2 PE=1 SV=2 4.14 1996.6 - 682951 - - - -3.9018 - 1.426 0.308 - 291.8 1 2 0 -0.0046 10 0 0 0 1.60E+08 1.01E+08 - - - 2.305 0.972 221125_WJC_METTL3_EV_vs_WT_F05.09057.09057.3 0.0876 Nov-40 K.EAIEGTYIDKK.C "sp|P62280|RS11_HUMAN,tr|M0QZC5|M0QZC5_HUMAN" 2 1265.6503 0.97 61719 9057 3 1265.646988 422.8907 40S ribosomal protein S11 OS=Homo sapiens OX=9606 GN=RPS11 PE=1 SV=3 4.68 1997.2 - 2.07E+06 - - - -2.6429 - 1.561 0.18 - 115.7 1 2 0 -0.0033 11 0 0 0 1.18E+08 1.22E+08 - - - 1.811 0.9965 221125_WJC_METTL3_EV_vs_WT_F05.09064.09064.3 0.000421 Nov-40 K.LR[166.11]EYEAALNSK[136.11].D "sp|P20700|LMNB1_HUMAN,tr|A0A0D9SFY5|A0A0D9SFY5_HUMAN,tr|E9PBF6|E9PBF6_HUMAN,tr|A0A0D9SFE5|A0A0D9SFE5_HUMAN" 4 1310.6949 1.14 61724 9064 3 1310.69136 437.9056 Lamin-B1 OS=Homo sapiens OX=9606 GN=LMNB1 PE=1 SV=2 6.14 1998.1 - 1.39E+06 - - - -2.7276 - 2.333 0.309 - 311 1 2 1 -0.0036 11 0 0 0 4.93E+07 4.32E+07 - - - 4.3907 0.991 221125_WJC_METTL3_EV_vs_WT_F05.09065.09065.2 0.000308 15/28 R.PVAPSGTALSTTSSK[136.11].L "sp|P35658|NU214_HUMAN,tr|A0A0A0MSW3|A0A0A0MSW3_HUMAN,tr|E9PKD2|E9PKD2_HUMAN,tr|B7ZAV2|B7ZAV2_HUMAN,tr|A0A494C1F2|A0A494C1F2_HUMAN,tr|H0Y837|H0Y837_HUMAN" 6 1410.7446 2.24 61725 9065 2 1410.742424 706.3796 Nuclear pore complex protein Nup214 OS=Homo sapiens OX=9606 GN=NUP214 PE=1 SV=2 9.18 1998.2 - 1.51E+06 - - - -1.524 - 2.839 0.501 - 573.5 1 1 0 -0.0022 15 0 0 0 6.02E+07 2.69E+07 - - - 5.3061 0.9985 221125_WJC_METTL3_EV_vs_WT_F05.09066.09066.2 0.0182 18-Jul K.ASPFEEDQNR[166.11].D "sp|Q8TB72|PUM2_HUMAN,tr|A0A0C4DG68|A0A0C4DG68_HUMAN,tr|C9JW01|C9JW01_HUMAN" 3 1201.5239 1.58 61726 9066 2 1201.523614 601.7692 Pumilio homolog 2 OS=Homo sapiens OX=9606 GN=PUM2 PE=1 SV=2 4.14 1998.3 - 1.72E+06 - - - -0.238 - 1.42 0.272 - 181.7 1 2 0 -0.0003 10 0 0 0 1.60E+08 1.01E+08 - - - 2.0287 0.9998 221125_WJC_METTL3_EV_vs_WT_F05.09067.09067.2 1.78E-05 20-Nov K.EAIEGTYIDK[136.11]K[136.11].C "sp|P62280|RS11_HUMAN,tr|M0QZC5|M0QZC5_HUMAN" 2 1281.6787 1.1 61727 9067 2 1281.680157 641.8466 40S ribosomal protein S11 OS=Homo sapiens OX=9606 GN=RPS11 PE=1 SV=3 4.68 1998.4 - 769774 - - - 1.111 - 2.145 0.476 - 501.4 1 2 0 0.0014 11 0 0 0 2.29E+07 2.09E+07 - - - 4.6208 0.9836 221125_WJC_METTL3_EV_vs_WT_F05.09068.09068.2 2.32 20-Nov K.LREYEAALNSK.D "sp|P20700|LMNB1_HUMAN,tr|A0A0D9SFY5|A0A0D9SFY5_HUMAN,tr|E9PBF6|E9PBF6_HUMAN,tr|A0A0D9SFE5|A0A0D9SFE5_HUMAN" 4 1292.6725 1.59 61728 9068 2 1292.66881 647.3435 Lamin-B1 OS=Homo sapiens OX=9606 GN=LMNB1 PE=1 SV=2 6.14 1998.6 - 442211 - - - -2.8275 - 2.38 0.262 - 411.5 1 2 1 -0.0037 11 0 0 0 1.15E+07 7.26E+06 - - - 3.3207 0.999 221125_WJC_METTL3_EV_vs_WT_F05.09071.09071.3 8.66 13/40 K.LREYEAALNSK.D "sp|P20700|LMNB1_HUMAN,tr|A0A0D9SFY5|A0A0D9SFY5_HUMAN,tr|E9PBF6|E9PBF6_HUMAN,tr|A0A0D9SFE5|A0A0D9SFE5_HUMAN" 4 1292.6725 1.12 61729 9071 3 1292.668951 431.8981 Lamin-B1 OS=Homo sapiens OX=9606 GN=LMNB1 PE=1 SV=2 6.14 1999 - 2.17E+06 - - - -2.7184 - 2.665 0.38 - 434 1 2 1 -0.0035 11 0 0 0 4.79E+07 4.29E+07 - - - 5.5602 0.9927 221125_WJC_METTL3_EV_vs_WT_F05.09072.09072.3 0.00916 Nov-36 R.RLDAEEAEIR.Q "sp|Q5VT06|CE350_HUMAN,tr|H0Y7F7|H0Y7F7_HUMAN" 2 1200.6099 0.48 61730 9072 3 1200.605031 401.2106 Centrosome-associated protein 350 OS=Homo sapiens OX=9606 GN=CEP350 PE=1 SV=1 4.41 1999.1 - 588825 - - - -4.0263 - 2.291 0.216 - 276.5 1 2 0 -0.0048 10 0 0 0 9.80E+06 2.04E+07 - - - 3.3679 0.9996 221125_WJC_METTL3_EV_vs_WT_F05.09073.09073.3 0.00269 Jul-36 R.YDEMVESMK[136.11]K[136.11].V "sp|P62258|1433E_HUMAN,tr|B4DJF2|B4DJF2_HUMAN,tr|I3L3T1|I3L3T1_HUMAN" 3 1274.5858 1.18 61731 9073 3 1274.582315 425.8692 14-3-3 protein epsilon OS=Homo sapiens OX=9606 GN=YWHAE PE=1 SV=1 4.68 1999.2 - 381458 - - - -2.7028 - 1.695 0.434 - 40.6 1 2 0 -0.0034 10 0 0 0 3.54E+07 3.01E+07 - - - 4.9188 0.9999 221125_WJC_METTL3_EV_vs_WT_F05.09074.09074.2 6.01E-05 22-Sep R.AQAQAQDAELVR.L sp|O15049|N4BP3_HUMAN 1 1298.6579 23.15 61732 9074 2 1298.6571 650.3362 NEDD4-binding protein 3 OS=Homo sapiens OX=9606 GN=N4BP3 PE=1 SV=3 4.37 1999.3 - 271846 - - - -0.5991 - 2.07 0.52 - 286.6 1 2 0 -0.0008 12 0 0 0 2.99E+06 1.29E+05 - - - 4.7958 0.9999 221125_WJC_METTL3_EV_vs_WT_F05.09077.09077.3 0.0001 13/48 R.LAQGHTTVDELAR.R "sp|Q15149|PLEC_HUMAN,tr|H0YDN1|H0YDN1_HUMAN" 2 1409.7263 8.81 61733 9077 3 1409.724297 470.916 Plectin OS=Homo sapiens OX=9606 GN=PLEC PE=1 SV=3 5.32 1999.7 - 4.53E+06 - - - -1.4152 - 2.492 0.363 - 321.6 1 2 0 -0.002 13 0 0 0 6.03E+08 6.85E+07 - - - 5.0622 0.9997 221125_WJC_METTL3_EV_vs_WT_F05.09079.09079.2 0.0277 20-Dec R.EAANLLEGHAR.A "sp|O00461|GOLI4_HUMAN,tr|F8W785|F8W785_HUMAN" 2 1179.5996 1.14 61735 9079 2 1179.600681 590.8071 Golgi integral membrane protein 4 OS=Homo sapiens OX=9606 GN=GOLIM4 PE=1 SV=1 5.4 2000 - 885370 - - - 0.8867 - 2.048 0.37 - 233.8 1 2 0 0.001 11 0 0 0 1.02E+07 8.99E+06 - - - 3.7128 0.989 221125_WJC_METTL3_EV_vs_WT_F05.09083.09083.2 0.00217 16-Dec K.RINVELSTK.G sp|Q96PK6|RBM14_HUMAN 1 1058.6084 1.82 61739 9083 2 1058.604189 530.3115 RNA-binding protein 14 OS=Homo sapiens OX=9606 GN=RBM14 PE=1 SV=2 8.75 2000.5 - 445969 - - - -3.9854 - 2.414 0.084 - 564.6 1 2 0 -0.0042 9 0 0 0 4.96E+08 2.73E+08 - - - 2.2097 0.9999 221125_WJC_METTL3_EV_vs_WT_F05.09087.09087.3 1.51E-08 14/44 R.VVASDK[136.11]ETYELR[166.11].Y "sp|Q6P5R6|RL22L_HUMAN,tr|H0Y8C2|H0Y8C2_HUMAN,tr|C9JYQ9|C9JYQ9_HUMAN" 3 1426.7423 1.28 61741 9087 3 1426.74082 476.588 60S ribosomal protein L22-like 1 OS=Homo sapiens OX=9606 GN=RPL22L1 PE=1 SV=2 4.68 2001 - 1.33E+06 - - - -1.0226 - 2.498 0.574 - 301.7 1 2 1 -0.0015 12 0 0 0 7.81E+08 6.11E+08 - - - 7.4767 0.9965 221125_WJC_METTL3_EV_vs_WT_F05.09088.09088.2 0.167 18-Nov K.ALELDSNNEK[136.11].G sp|Q02790|FKBP4_HUMAN 1 1139.555 1.15 61742 9088 2 1139.550423 570.7848 Peptidyl-prolyl cis-trans isomerase FKBP4 OS=Homo sapiens OX=9606 GN=FKBP4 PE=1 SV=3 4.14 2001.1 - 628109 - - - -4.0007 - 2.14 0.29 - 344 1 2 0 -0.0046 10 0 0 0 3.35E+07 2.92E+07 - - - 3.3051 0.9967 221125_WJC_METTL3_EV_vs_WT_F05.09090.09090.2 14.7 16-Aug R.K[136.11]AGIFQSVK[136.11].- sp|P09669|COX6C_HUMAN 1 992.599 0.62 61744 9090 2 992.598519 497.3068 Cytochrome c oxidase subunit 6C OS=Homo sapiens OX=9606 GN=COX6C PE=1 SV=2 10 2001.4 - 286684 - - - -0.4503 - 1.51 0.16 - 184.8 1 2 0 -0.0004 9 0 0 0 2.77E+06 4.44E+06 - - - 1.4149 0.9998 221125_WJC_METTL3_EV_vs_WT_F05.09093.09093.2 0.00571 16-Sep K.AQYEDIANR[166.11].S "sp|P05787|K2C8_HUMAN,sp|O95678|K2C75_HUMAN,tr|F8VUG2|F8VUG2_HUMAN" 3 1088.5126 1.51 61746 9093 2 1088.511744 545.2636 "Keratin, type II cytoskeletal 8 OS=Homo sapiens OX=9606 GN=KRT8 PE=1 SV=7" 4.37 2001.7 - 3.80E+06 - - - -0.7928 - 1.913 0.479 - 457.8 1 2 0 -0.0009 9 0 0 0 1.21E+08 8.04E+07 - - - 4.4553 0.9653 221125_WJC_METTL3_EV_vs_WT_F05.09094.09094.3 0.00163 Dec-44 R.VVIARPTPPQAR.P "sp|P46379|BAG6_HUMAN,tr|A0A7I2V508|A0A7I2V508_HUMAN,tr|A0A0G2JJ92|A0A0G2JJ92_HUMAN,tr|A0A0G2JJM1|A0A0G2JJM1_HUMAN,tr|X6REW1|X6REW1_HUMAN,tr|H0Y7K4|H0Y7K4_HUMAN,tr|A0A0G2JIA9|A0A0G2JIA9_HUMAN,tr|A0A7P0MQS5|A0A7P0MQS5_HUMAN,tr|A0A0G2JIB3|A0A0G2JIB3_HUMAN,tr|H0Y759|H0Y759_HUMAN,tr|A0A0G2JL47|A0A0G2JL47_HUMAN,tr|A0A024RCR6|A0A024RCR6_HUMAN,tr|A0A0G2JK23|A0A0G2JK23_HUMAN" 13 1303.7725 1.79 61747 9094 3 1303.770632 435.5981 Large proline-rich protein BAG6 OS=Homo sapiens OX=9606 GN=BAG6 PE=1 SV=2 12 2001.8 - 1.14E+06 - - - -1.3975 - 2.091 0.332 - 156.3 1 1 0 -0.0018 12 0 0 0 8.87E+07 4.95E+07 - - - 4.2856 0.9994 221125_WJC_METTL3_EV_vs_WT_F05.09097.09097.2 6.77E-07 13/22 R.EENAEQQALAAK.R sp|Q9UQE7|SMC3_HUMAN 1 1300.6259 0.93 61750 9097 2 1300.621708 651.3202 Structural maintenance of chromosomes protein 3 OS=Homo sapiens OX=9606 GN=SMC3 PE=1 SV=2 4.25 2002.1 - 557804 - - - -3.23 - 2.393 0.508 - 551.6 1 2 0 -0.0042 12 0 0 0 7.51E+07 8.09E+07 - - - 5.0876 0.9994 221125_WJC_METTL3_EV_vs_WT_F05.09105.09105.2 0.0123 20-Oct K.EAIEGTYIDKK.C "sp|P62280|RS11_HUMAN,tr|M0QZC5|M0QZC5_HUMAN" 2 1265.6503 1.1 61756 9105 2 1265.649906 633.8324 40S ribosomal protein S11 OS=Homo sapiens OX=9606 GN=RPS11 PE=1 SV=3 4.68 2003 - 1.63E+06 - - - -0.3374 - 1.722 0.318 - 322.3 1 2 0 -0.0004 11 0 0 0 2.29E+07 2.09E+07 - - - 2.8599 0.9999 221125_WJC_METTL3_EV_vs_WT_F05.09106.09106.2 2.11E-05 22-Nov R.NVESGEEELASK.L sp|Q96HS1|PGAM5_HUMAN 1 1290.5939 0.97 61757 9106 2 1290.593312 646.3042 "Serine\threonine-protein phosphatase PGAM5, mitochondrial OS=Homo sapiens OX=9606 GN=PGAM5 PE=1 SV=2" 4.09 2003.2 - 1.29E+06 - - - -0.4866 - 2.155 0.511 - 283.9 1 2 0 -0.0006 12 0 0 0 1.79E+08 1.85E+08 - - - 4.8352 1 221125_WJC_METTL3_EV_vs_WT_F05.09108.09108.2 3.21E-08 13/22 R.VVASDK[136.11]ETYELR[166.11].Y "sp|Q6P5R6|RL22L_HUMAN,tr|H0Y8C2|H0Y8C2_HUMAN,tr|C9JYQ9|C9JYQ9_HUMAN" 3 1426.7423 1.25 61759 9108 2 1426.74118 714.3784 60S ribosomal protein L22-like 1 OS=Homo sapiens OX=9606 GN=RPL22L1 PE=1 SV=2 4.68 2003.4 - 744771 - - - -0.7703 - 2.382 0.633 - 632.6 1 2 1 -0.0011 12 0 0 0 8.34E+07 6.70E+07 - - - 5.9997 0.9874 221125_WJC_METTL3_EV_vs_WT_F05.09109.09109.2 0.377 14-Aug R.QYFHQLEK[136.11].M "sp|P42704|LPPRC_HUMAN,tr|A0A804HI14|A0A804HI14_HUMAN,tr|A0A804HL40|A0A804HL40_HUMAN,tr|A0A804HKJ0|A0A804HKJ0_HUMAN,tr|A0A804HKR3|A0A804HKR3_HUMAN,tr|A0A804HIN4|A0A804HIN4_HUMAN,tr|A0A804HLG8|A0A804HLG8_HUMAN,tr|A0A804HIV5|A0A804HIV5_HUMAN,tr|A0A804HHY9|A0A804HHY9_HUMAN,tr|A0A804HJH8|A0A804HJH8_HUMAN,tr|B8ZZ38|B8ZZ38_HUMAN,tr|A0A804HI40|A0A804HI40_HUMAN,tr|A0A804HJZ1|A0A804HJZ1_HUMAN,tr|C9JCA9|C9JCA9_HUMAN,tr|A0A804HIQ7|A0A804HIQ7_HUMAN,tr|A0A804HK30|A0A804HK30_HUMAN,tr|A0A804HKI2|A0A804HKI2_HUMAN,tr|A0A804HJI0|A0A804HJI0_HUMAN,tr|A0A804HIG4|A0A804HIG4_HUMAN,tr|A0A804HK02|A0A804HK02_HUMAN" 20 1099.5542 1.83 61760 9109 2 1099.555377 550.7844 "Leucine-rich PPR motif-containing protein, mitochondrial OS=Homo sapiens OX=9606 GN=LRPPRC PE=1 SV=3" 6.75 2003.5 - 651804 - - - 1.0759 - 1.294 0.116 - 282 1 2 0 0.0012 8 0 0 0 2.11E+07 1.15E+07 - - - 0.6747 0.9992 221125_WJC_METTL3_EV_vs_WT_F05.09110.09110.3 0.0192 Dec-44 R.QAASSLQQASLK[136.11].L "sp|P38646|GRP75_HUMAN,tr|A0A7I2V2S7|A0A7I2V2S7_HUMAN,tr|A0A7I2V2G2|A0A7I2V2G2_HUMAN,tr|A0A7I2V3F7|A0A7I2V3F7_HUMAN,tr|A0A7I2YQB2|A0A7I2YQB2_HUMAN,tr|D6RCD7|D6RCD7_HUMAN" 6 1238.671 0.92 61761 9110 3 1238.669599 413.8976 "Stress-70 protein, mitochondrial OS=Homo sapiens OX=9606 GN=HSPA9 PE=1 SV=2" 8.75 2003.6 - 549806 - - - -1.1432 - 1.936 0.282 - 140.5 1 2 0 -0.0014 12 0 0 0 8.87E+06 9.64E+06 - - - 3.5148 0.9998 221125_WJC_METTL3_EV_vs_WT_F05.09115.09115.2 0.000296 16-Sep K.AQYEDIANR.S "sp|P05787|K2C8_HUMAN,sp|O95678|K2C75_HUMAN,tr|F8VUG2|F8VUG2_HUMAN" 3 1078.5043 1.51 61765 9115 2 1078.503959 540.2594 "Keratin, type II cytoskeletal 8 OS=Homo sapiens OX=9606 GN=KRT8 PE=1 SV=7" 4.37 2004.2 - 8.34E+06 - - - -0.3505 - 1.567 0.47 - 398.2 1 2 0 -0.0004 9 0 0 0 1.21E+08 8.04E+07 - - - 3.8118 0.9999 221125_WJC_METTL3_EV_vs_WT_F05.09117.09117.3 0.0533 15/44 R.VVASDKETYELR.Y "sp|Q6P5R6|RL22L_HUMAN,tr|H0Y8C2|H0Y8C2_HUMAN,tr|C9JYQ9|C9JYQ9_HUMAN" 3 1408.7198 1.28 61766 9117 3 1408.719479 470.5805 60S ribosomal protein L22-like 1 OS=Homo sapiens OX=9606 GN=RPL22L1 PE=1 SV=2 4.68 2004.5 - 1.52E+07 - - - -0.2343 - 2.903 0.454 - 364.8 1 2 1 -0.0003 12 0 0 0 7.84E+08 6.12E+08 - - - 6.5556 0.8556 221125_WJC_METTL3_EV_vs_WT_F05.09121.09121.2 0.102 18-Jun E.STGYMEPALR.C "sp|P21817|RYR1_HUMAN,tr|M0R1U6|M0R1U6_HUMAN" 2 1123.5332 5.85 61770 9121 2 1123.533256 562.7739 Ryanodine receptor 1 OS=Homo sapiens OX=9606 GN=RYR1 PE=1 SV=3 5.72 2004.7 - 1.82E+06 - - - 0.0552 - 1.411 0.207 - 150.9 1 1 0 0.0001 10 0 0 0 3.92E+07 6.71E+06 - - - 1.5309 1 221125_WJC_METTL3_EV_vs_WT_F05.09123.09123.2 2.27E-07 15/22 R.VVASDKETYELR.Y "sp|Q6P5R6|RL22L_HUMAN,tr|H0Y8C2|H0Y8C2_HUMAN,tr|C9JYQ9|C9JYQ9_HUMAN" 3 1408.7198 1.25 61772 9123 2 1408.717547 705.3672 60S ribosomal protein L22-like 1 OS=Homo sapiens OX=9606 GN=RPL22L1 PE=1 SV=2 4.68 2004.9 - 1.34E+06 - - - -1.6057 - 2.557 0.574 - 765.6 1 2 1 -0.0023 12 0 0 0 8.37E+07 6.72E+07 - - - 5.7501 0.9989 221125_WJC_METTL3_EV_vs_WT_F05.09129.09129.2 0.00179 20-Aug K.EPPSSPLQPQK.E "sp|Q92615|LAR4B_HUMAN,tr|A0A087X183|A0A087X183_HUMAN,tr|H0Y4V9|H0Y4V9_HUMAN" 3 1206.6245 1.6 61777 9129 2 1206.624356 604.3195 La-related protein 4B OS=Homo sapiens OX=9606 GN=LARP4B PE=1 SV=3 6.1 2005.5 - 2.40E+06 - - - -0.0796 - 1.654 0.252 - 206.5 1 2 0 -0.0001 11 0 0 0 7.92E+07 4.95E+07 - - - 2.2635 0.9993 221125_WJC_METTL3_EV_vs_WT_F05.09130.09130.2 0.0101 14-Aug K.DLSFGHSR.A sp|Q13835|PKP1_HUMAN 1 917.4355 32.74 61778 9130 2 917.434562 459.725 Plakophilin-1 OS=Homo sapiens OX=9606 GN=PKP1 PE=1 SV=2 6.74 2005.7 - 526403 - - - -1.054 - 1.392 0.392 - 245.9 1 2 0 -0.001 8 0 0 0 8.51E+06 2.60E+05 - - - 2.9335 0.9943 221125_WJC_METTL3_EV_vs_WT_F05.09131.09131.2 2.80E-07 24-Nov E.IDAC[160.03]MDSEAPGSK[136.11].D "sp|Q86U44|MTA70_HUMAN,tr|H0YFV6|H0YFV6_HUMAN" 2 1387.5839 0.001 61779 9131 2 1387.583957 694.7992 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 4.03 2005.8 - 349244 - - - 0.0295 - 2.35 0.556 - 335.4 1 1 0 0 13 0 0 0 0.00E+00 1.50E+07 - - - 5.3405 0.8437 221125_WJC_METTL3_EV_vs_WT_F05.09136.09136.2 0.0314 20-May D.VSDAMTDHEMK[136.11].G "sp|P35670|ATP7B_HUMAN,tr|E7ET55|E7ET55_HUMAN,tr|A0A669KA36|A0A669KA36_HUMAN,tr|F5H748|F5H748_HUMAN,tr|B7ZLR4|B7ZLR4_HUMAN,tr|A0A669KB88|A0A669KB88_HUMAN,tr|F5H562|F5H562_HUMAN" 7 1270.5413 0.01 61781 9136 2 1270.541152 636.2779 Copper-transporting ATPase 2 OS=Homo sapiens OX=9606 GN=ATP7B PE=1 SV=4 4.54 2006.5 - 546369 - - - -0.1346 - 1.019 0.338 - 45.4 2 1 0 -0.0002 11 0 0 0 1.57E+05 1.69E+07 - - - 1.4539 0.9965 221125_WJC_METTL3_EV_vs_WT_F05.09137.09137.2 0.0177 16-Aug K.LITEDVQGK[136.11].N "sp|P61247|RS3A_HUMAN,tr|H0Y8L7|H0Y8L7_HUMAN,tr|D6RED7|D6RED7_HUMAN,tr|D6RGE0|D6RGE0_HUMAN,tr|D6RAS7|D6RAS7_HUMAN,tr|D6RB09|D6RB09_HUMAN,tr|E9PFI5|E9PFI5_HUMAN,tr|D6RAT0|D6RAT0_HUMAN,tr|D6RG13|D6RG13_HUMAN" 9 1009.5535 2.01 61782 9137 2 1009.554338 505.784 40S ribosomal protein S3a OS=Homo sapiens OX=9606 GN=RPS3A PE=1 SV=2 4.37 2006.6 - 327651 - - - 0.8043 - 1.154 0.279 - 153 1 2 0 0.0008 9 0 0 0 7.96E+06 3.96E+06 - - - 1.5158 0.9993 221125_WJC_METTL3_EV_vs_WT_F05.09141.09141.2 0.0012 16-Jun K.DNYPQSVPR[166.11].L "sp|O00159|MYO1C_HUMAN,tr|F5H6E2|F5H6E2_HUMAN" 2 1084.5177 0.66 61784 9141 2 1084.517641 543.2661 Unconventional myosin-Ic OS=Homo sapiens OX=9606 GN=MYO1C PE=1 SV=4 5.84 2007.1 - 716208 - - - -0.0479 - 1.528 0.337 - 158.8 1 2 0 -0.0001 9 0 0 0 8.02E+06 1.21E+07 - - - 2.7566 0.9997 221125_WJC_METTL3_EV_vs_WT_F05.09142.09142.2 3.44E-06 22-Oct R.YLQSDNNTALC[160.03]K[136.11].V sp|O75529|TAF5L_HUMAN 1 1433.67 0.91 61785 9142 2 1433.666953 717.8423 TAF5-like RNA polymerase II p300\CBP-associated factor-associated factor 65 kDa subunit 5L OS=Homo sapiens OX=9606 GN=TAF5L PE=1 SV=1 5.83 2007.3 - 260425 - - - -2.1455 - 1.964 0.584 - 242.8 1 2 0 -0.0031 12 0 0 0 1.08E+07 1.18E+07 - - - 5.1295 0.9998 221125_WJC_METTL3_EV_vs_WT_F05.09149.09149.2 0.00152 14/24 R.GAGSAMSTDAYPK.N "sp|O95721|SNP29_HUMAN,tr|C9JAF7|C9JAF7_HUMAN" 2 1254.5551 2.64 61789 9149 2 1254.552588 628.2848 Synaptosomal-associated protein 29 OS=Homo sapiens OX=9606 GN=SNAP29 PE=1 SV=1 5.83 2008.1 - 1.05E+06 - - - -1.964 - 2.832 0.537 - 692 1 2 0 -0.0025 13 0 0 0 2.68E+07 1.02E+07 - - - 5.6782 0.9997 221125_WJC_METTL3_EV_vs_WT_F05.09151.09151.2 2.63E-05 16-Aug K.DYSDITSSK.- sp|P29084|T2EB_HUMAN 1 1014.4506 1.83 61791 9151 2 1014.44918 508.2326 Transcription initiation factor IIE subunit beta OS=Homo sapiens OX=9606 GN=GTF2E2 PE=1 SV=1 4.21 2008.4 - 670252 - - - -1.3702 - 1.531 0.51 - 189.7 1 2 0 -0.0014 9 0 0 0 1.90E+07 1.03E+07 - - - 4.0396 0.9759 221125_WJC_METTL3_EV_vs_WT_F05.09155.09155.2 0.00907 15/18 S.RSLYGLGGSK.R "sp|P48668|K2C6C_HUMAN,sp|P04259|K2C6B_HUMAN,sp|P02538|K2C6A_HUMAN" 3 1036.5665 3.36 61793 9155 2 1036.565157 519.2905 "Keratin, type II cytoskeletal 6C OS=Homo sapiens OX=9606 GN=KRT6C PE=1 SV=3" 9.99 2008.8 - 1.51E+06 - - - -1.3371 - 2.307 0.303 - 649.6 1 1 0 -0.0014 10 0 0 0 1.19E+08 3.55E+07 - - - 3.6119 0.9764 221125_WJC_METTL3_EV_vs_WT_F05.09157.09157.2 3.97 12-Jul K.QHYIDLK[136.11].D "sp|O60361|NDK8_HUMAN,sp|P22392|NDKB_HUMAN,tr|Q32Q12|Q32Q12_HUMAN,tr|J3KPD9|J3KPD9_HUMAN,tr|F6XY72|F6XY72_HUMAN" 5 923.4956 1.23 61795 9157 2 923.494909 462.7551 Putative nucleoside diphosphate kinase OS=Homo sapiens OX=9606 GN=NME2P1 PE=5 SV=1 6.74 2009 - 1.23E+06 - - - -0.7667 - 1.095 0.106 - 243.3 1 2 0 -0.0007 7 0 0 0 1.33E+08 1.08E+08 - - - 0.1113 0.999 221125_WJC_METTL3_EV_vs_WT_F05.09158.09158.2 0.000659 18-Oct K.STLADYSAQK.D "sp|Q9UKV3|ACINU_HUMAN,tr|S4R3H4|S4R3H4_HUMAN,tr|E7EQT4|E7EQT4_HUMAN" 3 1082.5244 1.69 61796 9158 2 1082.521226 542.2695 Apoptotic chromatin condensation inducer in the nucleus OS=Homo sapiens OX=9606 GN=ACIN1 PE=1 SV=2 5.55 2009.2 - 1.06E+06 - - - -2.9357 - 2.045 0.385 - 282.3 1 2 0 -0.0032 10 0 0 0 4.44E+07 2.62E+07 - - - 3.8805 0.9999 221125_WJC_METTL3_EV_vs_WT_F05.09164.09164.2 0.00342 16-Nov K.R[166.11]INVELSTK[136.11].G sp|Q96PK6|RBM14_HUMAN 1 1076.6309 1.82 61800 9164 2 1076.630207 539.3227 RNA-binding protein 14 OS=Homo sapiens OX=9606 GN=RBM14 PE=1 SV=2 8.75 2009.8 - 6.76E+06 - - - -0.6232 - 2.327 0.42 - 487.3 1 2 0 -0.0007 9 0 0 0 4.96E+08 2.73E+08 - - - 4.5863 0.9979 221125_WJC_METTL3_EV_vs_WT_F05.09165.09165.2 0.0468 12-Jul K.QHYIDLK.D "sp|O60361|NDK8_HUMAN,sp|P22392|NDKB_HUMAN,tr|Q32Q12|Q32Q12_HUMAN,tr|J3KPD9|J3KPD9_HUMAN,tr|F6XY72|F6XY72_HUMAN" 5 915.4814 1.23 61801 9165 2 915.481342 458.748 Putative nucleoside diphosphate kinase OS=Homo sapiens OX=9606 GN=NME2P1 PE=5 SV=1 6.74 2009.9 - 1.67E+06 - - - -0.0819 - 1.289 0.256 - 271.2 1 2 0 -0.0001 7 0 0 0 1.33E+08 1.08E+08 - - - 1.7362 0.9969 221125_WJC_METTL3_EV_vs_WT_F05.09166.09166.2 0.00798 16-Sep K.EQLQGLNDR.F "sp|Q16352|AINX_HUMAN,sp|P07197|NFM_HUMAN,tr|E7ESP9|E7ESP9_HUMAN,tr|E7EMV2|E7EMV2_HUMAN" 4 1071.5309 2.76 61802 9166 2 1071.531619 536.7727 Alpha-internexin OS=Homo sapiens OX=9606 GN=INA PE=1 SV=2 4.37 2010 - 1.18E+06 - - - 0.6841 - 1.604 0.156 - 405.2 1 2 0 0.0007 9 0 0 0 1.08E+08 3.91E+07 - - - 1.56 0.9987 221125_WJC_METTL3_EV_vs_WT_F05.09167.09167.3 0.216 Aug-40 K.LVDEEPQLTKR.T sp|Q9UG63|ABCF2_HUMAN 1 1326.7143 0.63 61803 9167 3 1326.713262 443.2454 ATP-binding cassette sub-family F member 2 OS=Homo sapiens OX=9606 GN=ABCF2 PE=1 SV=2 4.68 2010.1 - 588071 - - - -0.805 - 1.588 0.292 - 79 1 2 0 -0.0011 11 0 0 0 9.78E+06 1.55E+07 - - - 3.109 0.9988 221125_WJC_METTL3_EV_vs_WT_F05.09168.09168.2 3.25E-06 22-Nov K.TSLSANNATLEK.Q "sp|O75330|HMMR_HUMAN,tr|E5RIH2|E5RIH2_HUMAN,tr|E5RI30|E5RI30_HUMAN" 3 1247.6357 1.29 61804 9168 2 1247.630286 624.8251 Hyaluronan mediated motility receptor OS=Homo sapiens OX=9606 GN=HMMR PE=1 SV=2 5.66 2010.3 - 573988 - - - -4.3755 - 2.369 0.526 - 472.3 1 2 0 -0.0055 12 0 0 0 1.07E+07 8.27E+06 - - - 5.1936 0.9999 221125_WJC_METTL3_EV_vs_WT_F05.09169.09169.2 3.12E-07 18-Oct R.SSFSHYSGLK.H sp|Q8NC51|PAIRB_HUMAN 1 1111.5298 0.51 61805 9169 2 1111.52906 556.7722 Plasminogen activator inhibitor 1 RNA-binding protein OS=Homo sapiens OX=9606 GN=SERBP1 PE=1 SV=2 8.33 2010.4 - 248513 - - - -0.6873 - 2.017 0.555 - 271.4 1 2 0 -0.0008 10 0 0 0 2.40E+07 4.75E+07 - - - 5.0984 1 221125_WJC_METTL3_EV_vs_WT_F05.09172.09172.2 3.88E-06 20-Nov R.INISEGNC[160.03]PER.L "sp|P57721|PCBP3_HUMAN,sp|Q15366|PCBP2_HUMAN,sp|Q15365|PCBP1_HUMAN,tr|F8VTZ0|F8VTZ0_HUMAN,tr|F8W1G6|F8W1G6_HUMAN,tr|E9PFP8|E9PFP8_HUMAN,tr|J3QT27|J3QT27_HUMAN,tr|F8VZX2|F8VZX2_HUMAN,tr|F8W0G4|F8W0G4_HUMAN,tr|F8VXH9|F8VXH9_HUMAN,tr|H3BRU6|H3BRU6_HUMAN" 11 1287.5877 0.83 61806 9172 2 1287.58667 644.8012 Poly(rC)-binding protein 3 OS=Homo sapiens OX=9606 GN=PCBP3 PE=1 SV=2 4.53 2010.8 - 7.13E+06 - - - -0.8388 - 2.439 0.596 - 460.6 1 2 0 -0.0011 11 0 0 0 2.80E+08 3.37E+08 - - - 5.8547 0.9991 221125_WJC_METTL3_EV_vs_WT_F05.09173.09173.2 0.000126 22-Sep K.YSPGYNTEVGDK.W "sp|O95299|NDUAA_HUMAN,tr|A0A7I2YQU0|A0A7I2YQU0_HUMAN,tr|E7ESZ7|E7ESZ7_HUMAN,tr|A0A7I2V3H5|A0A7I2V3H5_HUMAN,tr|A0A087WXC5|A0A087WXC5_HUMAN,tr|A0A7I2V594|A0A7I2V594_HUMAN" 6 1328.5885 1 61807 9173 2 1328.584106 665.3015 "NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 10, mitochondrial OS=Homo sapiens OX=9606 GN=NDUFA10 PE=1 SV=1" 4.37 2010.9 - 890218 - - - -3.2779 - 1.811 0.52 - 212.5 1 2 0 -0.0044 12 0 0 0 3.19E+07 3.20E+07 - - - 4.4429 0.9997 221125_WJC_METTL3_EV_vs_WT_F05.09174.09174.2 0.000177 22-Nov K.YSPGYNTEVGDK[136.11].W "sp|O95299|NDUAA_HUMAN,tr|A0A7I2YQU0|A0A7I2YQU0_HUMAN,tr|E7ESZ7|E7ESZ7_HUMAN,tr|A0A7I2V3H5|A0A7I2V3H5_HUMAN,tr|A0A087WXC5|A0A087WXC5_HUMAN,tr|A0A7I2V594|A0A7I2V594_HUMAN" 6 1336.6027 1 61808 9174 2 1336.600091 669.3086 "NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 10, mitochondrial OS=Homo sapiens OX=9606 GN=NDUFA10 PE=1 SV=1" 4.37 2011.1 - 608435 - - - -1.9228 - 1.996 0.518 - 319.1 1 2 0 -0.0026 12 0 0 0 3.19E+07 3.20E+07 - - - 4.6847 0.9996 221125_WJC_METTL3_EV_vs_WT_F05.09175.09175.3 0.135 14/40 K.VEAIDVEEAK[136.11]R[166.11].L "sp|P33991|MCM4_HUMAN,tr|A0A3B3IT92|A0A3B3IT92_HUMAN,tr|A0A3B3IU45|A0A3B3IU45_HUMAN,tr|E5RG31|E5RG31_HUMAN,tr|A0A3B3IS57|A0A3B3IS57_HUMAN" 5 1275.679 1.63 61809 9175 3 1275.676196 426.2336 DNA replication licensing factor MCM4 OS=Homo sapiens OX=9606 GN=MCM4 PE=1 SV=5 4.41 2011.2 - 511531 - - - -2.1596 - 2.659 0.3 - 373.1 1 2 0 -0.0028 11 0 0 0 1.25E+07 7.69E+06 - - - 4.6621 0.9996 221125_WJC_METTL3_EV_vs_WT_F05.09176.09176.2 0.00171 20-Nov K.C[160.03]AAVDVEPPSK.Q "sp|Q15020|SART3_HUMAN,tr|A0A499FI31|A0A499FI31_HUMAN" 2 1171.5543 1.79 61810 9176 2 1171.553915 586.7844 Squamous cell carcinoma antigen recognized by T-cells 3 OS=Homo sapiens OX=9606 GN=SART3 PE=1 SV=1 4.37 2011.3 - 444194 - - - -0.3491 - 1.496 0.412 - 321.7 1 2 0 -0.0004 11 0 0 0 1.68E+07 9.41E+06 - - - 3.1736 0.9998 221125_WJC_METTL3_EV_vs_WT_F05.09180.09180.2 3.37E-06 20-Nov R.INISEGNC[160.03]PER[166.11].L "sp|P57721|PCBP3_HUMAN,sp|Q15366|PCBP2_HUMAN,sp|Q15365|PCBP1_HUMAN,tr|F8VTZ0|F8VTZ0_HUMAN,tr|F8W1G6|F8W1G6_HUMAN,tr|E9PFP8|E9PFP8_HUMAN,tr|J3QT27|J3QT27_HUMAN,tr|F8VZX2|F8VZX2_HUMAN,tr|F8W0G4|F8W0G4_HUMAN,tr|F8VXH9|F8VXH9_HUMAN,tr|H3BRU6|H3BRU6_HUMAN" 11 1297.596 0.83 61812 9180 2 1297.595396 649.8053 Poly(rC)-binding protein 3 OS=Homo sapiens OX=9606 GN=PCBP3 PE=1 SV=2 4.53 2011.8 - 8.05E+06 - - - -0.4809 - 2.412 0.399 - 397.4 1 2 0 -0.0006 11 0 0 0 2.81E+08 3.37E+08 - - - 4.3697 0.9991 221125_WJC_METTL3_EV_vs_WT_F05.09181.09181.2 0.00521 16-Aug K.DYSDITSSK[136.11].- sp|P29084|T2EB_HUMAN 1 1022.4648 1.83 61813 9181 2 1022.463346 512.2397 Transcription initiation factor IIE subunit beta OS=Homo sapiens OX=9606 GN=GTF2E2 PE=1 SV=1 4.21 2011.9 - 414733 - - - -1.3927 - 1.307 0.404 - 199.1 1 2 0 -0.0014 9 0 0 0 1.90E+07 1.03E+07 - - - 2.7991 0.9999 221125_WJC_METTL3_EV_vs_WT_F05.09182.09182.3 0.00261 Nov-40 R.GLLVDRPSETK.T "sp|Q9UKV3|ACINU_HUMAN,tr|G3V3B0|G3V3B0_HUMAN,tr|S4R3H4|S4R3H4_HUMAN,tr|E7EQT4|E7EQT4_HUMAN" 4 1213.6667 1.34 61814 9182 3 1213.667254 405.5628 Apoptotic chromatin condensation inducer in the nucleus OS=Homo sapiens OX=9606 GN=ACIN1 PE=1 SV=2 6.07 2011.9 - 5.72E+06 - - - 0.496 - 2.328 0.35 - 161.6 1 2 0 0.0006 11 0 0 0 1.18E+08 8.78E+07 - - - 4.8425 0.9998 221125_WJC_METTL3_EV_vs_WT_F05.09183.09183.3 0.00214 Sep-36 K.TYEHFNAMGK.Y "sp|P16435|NCPR_HUMAN,tr|H0Y4R2|H0Y4R2_HUMAN" 2 1196.5284 1.13 61815 9183 3 1196.525674 399.8501 NADPH--cytochrome P450 reductase OS=Homo sapiens OX=9606 GN=POR PE=1 SV=2 6.41 2012 - 710153 - - - -2.3142 - 1.724 0.469 - 105.8 1 2 0 -0.0028 10 0 0 0 1.03E+07 9.12E+06 - - - 5.3587 0.9991 221125_WJC_METTL3_EV_vs_WT_F05.09184.09184.2 0.0723 16-Sep K.QLTQLINK[136.11]K[136.11].E "sp|Q15643|TRIPB_HUMAN,tr|H0YJ97|H0YJ97_HUMAN" 2 1100.6888 1.15 61816 9184 2 1100.688559 551.3517 Thyroid receptor-interacting protein 11 OS=Homo sapiens OX=9606 GN=TRIP11 PE=1 SV=3 10 2012.2 - 632561 - - - -0.2589 - 1.618 0.278 - 332.7 1 2 0 -0.0003 9 0 0 0 2.21E+07 1.93E+07 - - - 2.4863 0.9998 221125_WJC_METTL3_EV_vs_WT_F05.09185.09185.3 0.00028 Nov-40 K.VEAIDVEEAKR.L "sp|P33991|MCM4_HUMAN,tr|A0A3B3IT92|A0A3B3IT92_HUMAN,tr|A0A3B3IU45|A0A3B3IU45_HUMAN,tr|E5RG31|E5RG31_HUMAN,tr|A0A3B3IS57|A0A3B3IS57_HUMAN" 5 1257.6565 1.59 61817 9185 3 1257.654384 420.2261 DNA replication licensing factor MCM4 OS=Homo sapiens OX=9606 GN=MCM4 PE=1 SV=5 4.41 2012.3 - 623822 - - - -1.6674 - 2.447 0.349 - 244.7 1 2 0 -0.0021 11 0 0 0 1.23E+07 7.69E+06 - - - 4.9726 0.847 221125_WJC_METTL3_EV_vs_WT_F05.09186.09186.2 2.69 16-Jun R.K[136.11]EDVLSTSK[136.11].D "sp|P54132|BLM_HUMAN,tr|A0A7P0TBM9|A0A7P0TBM9_HUMAN,tr|A0A3B3IT82|A0A3B3IT82_HUMAN,tr|H0YNU5|H0YNU5_HUMAN,tr|H0YLV8|H0YLV8_HUMAN" 5 1021.5626 0.61 61818 9186 2 1021.567163 511.7886 Bloom syndrome protein OS=Homo sapiens OX=9606 GN=BLM PE=1 SV=1 6.07 2012.4 - 414733 - - - 4.4275 - 1.239 0.102 - 97.6 1 2 0 0.0045 9 0 0 0 5.48E+06 8.99E+06 - - - 0.4129 0.9994 221125_WJC_METTL3_EV_vs_WT_F05.09187.09187.3 0.000422 Nov-40 R.RVVIVDPETNK.E sp|P15924|DESP_HUMAN 1 1268.7089 19.69 61819 9187 3 1268.70514 423.9102 Desmoplakin OS=Homo sapiens OX=9606 GN=DSP PE=1 SV=3 6.07 2012.5 - 252643 - - - -2.925 - 2.003 0.375 - 162.2 1 2 0 -0.0037 11 0 0 0 7.04E+06 3.57E+05 - - - 4.6932 0.9945 221125_WJC_METTL3_EV_vs_WT_F05.09189.09189.2 0.692 18-Jun K.DLPVSEQQER.A "sp|Q9UNM6|PSD13_HUMAN,tr|J3KNQ3|J3KNQ3_HUMAN,tr|E9PL38|E9PL38_HUMAN,tr|H0YD73|H0YD73_HUMAN,tr|A0A087WUL9|A0A087WUL9_HUMAN" 5 1199.5782 0.8 61820 9189 2 1199.578704 600.7964 26S proteasome non-ATPase regulatory subunit 13 OS=Homo sapiens OX=9606 GN=PSMD13 PE=1 SV=2 4.14 2012.8 - 664922 - - - 0.3951 - 1.286 0.198 - 107.5 2 2 0 0.0005 10 0 0 0 5.55E+07 6.94E+07 - - - 1.0709 0.9999 221125_WJC_METTL3_EV_vs_WT_F05.09191.09191.2 8.43E-07 18-Nov R.SSFSHYSGLK[136.11].H sp|Q8NC51|PAIRB_HUMAN 1 1119.544 0.66 61821 9191 2 1119.544076 560.7793 Plasminogen activator inhibitor 1 RNA-binding protein OS=Homo sapiens OX=9606 GN=SERBP1 PE=1 SV=2 8.33 2013 - 1.94E+06 - - - 0.0464 - 2.053 0.589 - 342.3 1 2 0 0.0001 10 0 0 0 2.34E+07 3.55E+07 - - - 5.3991 0.9998 221125_WJC_METTL3_EV_vs_WT_F05.09192.09192.2 1.87E-05 18-Nov R.QGDNC[160.03]DSIIR.R "sp|Q9P2J5|SYLC_HUMAN,tr|A0A6I8PIV1|A0A6I8PIV1_HUMAN,tr|A0A6I8PRS0|A0A6I8PRS0_HUMAN,tr|A0A6I8PLB8|A0A6I8PLB8_HUMAN,tr|A0A6I8PIT3|A0A6I8PIT3_HUMAN,tr|A0A6I8PLB3|A0A6I8PLB3_HUMAN,tr|A0A6I8PS05|A0A6I8PS05_HUMAN,tr|B4DER1|B4DER1_HUMAN,tr|A0A6I8PL42|A0A6I8PL42_HUMAN" 9 1176.5193 1.53 61822 9192 2 1176.521608 589.2669 "Leucine--tRNA ligase, cytoplasmic OS=Homo sapiens OX=9606 GN=LARS1 PE=1 SV=2" 4.21 2013.1 - 662995 - - - 1.9311 - 2.178 0.532 - 558.6 1 2 0 0.0023 10 0 0 0 2.30E+07 1.50E+07 - - - 5.1424 0.9997 221125_WJC_METTL3_EV_vs_WT_F05.09196.09196.3 0.00456 Oct-44 R.TLVAVK[136.11]PDGVQR[166.11].R "sp|O00746|NDKM_HUMAN,tr|Q4TT34|Q4TT34_HUMAN,tr|A0A087WVT9|A0A087WVT9_HUMAN,tr|H0Y6J0|H0Y6J0_HUMAN,tr|F2Z2X0|F2Z2X0_HUMAN" 5 1299.763 1.61 61824 9196 3 1299.761616 434.2616 "Nucleoside diphosphate kinase, mitochondrial OS=Homo sapiens OX=9606 GN=NME4 PE=1 SV=1" 8.41 2013.6 - 578178 - - - -1.0302 - 1.915 0.341 - 109 1 2 0 -0.0013 12 0 0 0 2.83E+07 1.76E+07 - - - 4.1424 0.987 221125_WJC_METTL3_EV_vs_WT_F05.09197.09197.2 0.000324 14-Oct S.FSHYSGLK[136.11].H sp|Q8NC51|PAIRB_HUMAN 1 945.48 0.62 61825 9197 2 945.479669 473.7473 Plasminogen activator inhibitor 1 RNA-binding protein OS=Homo sapiens OX=9606 GN=SERBP1 PE=1 SV=2 8.6 2013.8 - 545913 - - - -0.3152 - 1.776 0.431 - 420.2 1 1 0 -0.0003 8 0 0 0 6.48E+06 1.04E+07 - - - 3.9565 0.9988 221125_WJC_METTL3_EV_vs_WT_F05.09204.09204.2 0.00476 18-Sep K.DTTVGTLSQR.L sp|P51665|PSMD7_HUMAN 1 1076.5462 0.57 61830 9204 2 1076.547212 539.2804 26S proteasome non-ATPase regulatory subunit 7 OS=Homo sapiens OX=9606 GN=PSMD7 PE=1 SV=2 5.84 2014.5 - 1.02E+06 - - - 0.9382 - 1.366 0.346 - 267.7 1 2 0 0.001 10 0 0 0 1.82E+07 3.21E+07 - - - 2.4668 0.9919 221125_WJC_METTL3_EV_vs_WT_F05.09207.09207.2 0.121 18-Aug R.STTLDAGNIK.L "sp|O75400|PR40A_HUMAN,tr|A0A7N4I394|A0A7N4I394_HUMAN" 2 1018.5295 0.63 61833 9207 2 1018.53127 510.272 Pre-mRNA-processing factor 40 homolog A OS=Homo sapiens OX=9606 GN=PRPF40A PE=1 SV=2 5.55 2014.8 - 269648 - - - 1.7486 - 1.394 0.173 - 223.9 1 2 0 0.0018 10 0 0 0 5.04E+06 7.94E+06 - - - 1.2454 0.9908 221125_WJC_METTL3_EV_vs_WT_F05.09208.09208.2 2.74 14-Jul R.RILQSLEK.M sp|P49790|NU153_HUMAN 1 985.592 1.31 61834 9208 2 985.593681 493.8033 Nuclear pore complex protein Nup153 OS=Homo sapiens OX=9606 GN=NUP153 PE=1 SV=2 8.75 2015 - 203621 - - - 1.6751 - 1.43 0.136 - 171.1 1 2 0 0.0017 8 0 0 0 2.83E+07 2.15E+07 - - - 1.1237 0.9981 221125_WJC_METTL3_EV_vs_WT_F05.09212.09212.2 0.000694 18-Dec K.LKGDDLQAIK.Q "sp|P0DMR1|HNRC4_HUMAN,sp|P07910|HNRPC_HUMAN,sp|O60812|HNRC1_HUMAN,sp|B2RXH8|HNRC2_HUMAN,sp|B7ZW38|HNRC3_HUMAN,tr|B4DY08|B4DY08_HUMAN,tr|G3V5V7|G3V5V7_HUMAN,tr|B2R5W2|B2R5W2_HUMAN,tr|G3V4C1|G3V4C1_HUMAN,tr|A0A0G2JPF8|A0A0G2JPF8_HUMAN,tr|A0A0G2JNQ3|A0A0G2JNQ3_HUMAN,tr|G3V576|G3V576_HUMAN,tr|G3V2D6|G3V2D6_HUMAN,tr|G3V4W0|G3V4W0_HUMAN,tr|G3V2Q1|G3V2Q1_HUMAN" 15 1099.6237 1.6 61836 9212 2 1099.623936 550.8191 Heterogeneous nuclear ribonucleoprotein C-like 4 OS=Homo sapiens OX=9606 GN=HNRNPCL4 PE=3 SV=1 5.96 2015.5 - 2.32E+06 - - - 0.1928 - 2.07 0.439 - 258.3 1 2 1 0.0002 10 0 0 0 2.24E+08 1.40E+08 - - - 4.3142 0.9972 221125_WJC_METTL3_EV_vs_WT_F05.09213.09213.2 0.00065 18-Sep R.DKVVALAEGR.E "sp|Q8N6T3|ARFG1_HUMAN,tr|F8VWB3|F8VWB3_HUMAN,tr|F8VWH9|F8VWH9_HUMAN,tr|E5RHT6|E5RHT6_HUMAN,tr|F8W1U7|F8W1U7_HUMAN,tr|E5RHC5|E5RHC5_HUMAN" 6 1056.5928 1.77 61837 9213 2 1056.593303 529.3037 ADP-ribosylation factor GTPase-activating protein 1 OS=Homo sapiens OX=9606 GN=ARFGAP1 PE=1 SV=2 6.07 2015.6 - 2.02E+06 - - - 0.5158 - 2.011 0.397 - 272.2 1 2 1 0.0005 10 0 0 0 4.33E+08 2.45E+08 - - - 3.9232 0.9947 221125_WJC_METTL3_EV_vs_WT_F05.09214.09214.2 0.00193 18-Sep K.LK[136.11]GDDLQAIK[136.11].Q "sp|P0DMR1|HNRC4_HUMAN,sp|P07910|HNRPC_HUMAN,sp|O60812|HNRC1_HUMAN,sp|B2RXH8|HNRC2_HUMAN,sp|B7ZW38|HNRC3_HUMAN,tr|B4DY08|B4DY08_HUMAN,tr|G3V5V7|G3V5V7_HUMAN,tr|B2R5W2|B2R5W2_HUMAN,tr|G3V4C1|G3V4C1_HUMAN,tr|A0A0G2JPF8|A0A0G2JPF8_HUMAN,tr|A0A0G2JNQ3|A0A0G2JNQ3_HUMAN,tr|G3V576|G3V576_HUMAN,tr|G3V2D6|G3V2D6_HUMAN,tr|G3V4W0|G3V4W0_HUMAN,tr|G3V2Q1|G3V2Q1_HUMAN" 15 1115.6521 1.6 61838 9214 2 1115.652813 558.8333 Heterogeneous nuclear ribonucleoprotein C-like 4 OS=Homo sapiens OX=9606 GN=HNRNPCL4 PE=3 SV=1 5.96 2015.7 - 2.24E+06 - - - 0.6176 - 1.722 0.359 - 133.8 1 2 1 0.0007 10 0 0 0 2.24E+08 1.40E+08 - - - 3.2094 0.9993 221125_WJC_METTL3_EV_vs_WT_F05.09215.09215.2 0.0104 18-Sep K.DTTVGTLSQR[166.11].L sp|P51665|PSMD7_HUMAN 1 1086.5545 0.58 61839 9215 2 1086.555194 544.2845 26S proteasome non-ATPase regulatory subunit 7 OS=Homo sapiens OX=9606 GN=PSMD7 PE=1 SV=2 5.84 2015.7 - 1.92E+06 - - - 0.6645 - 1.702 0.307 - 254.8 1 2 0 0.0007 10 0 0 0 1.86E+07 3.20E+07 - - - 2.7927 0.999 221125_WJC_METTL3_EV_vs_WT_F05.09216.09216.3 0.000644 13/36 R.QAVDVSPLR[166.11]R[166.11].V "sp|P46782|RS5_HUMAN,tr|M0QZN2|M0QZN2_HUMAN,tr|M0R0F0|M0R0F0_HUMAN,tr|M0R0R2|M0R0R2_HUMAN" 4 1159.6576 0.94 61840 9216 3 1159.657949 387.5598 40S ribosomal protein S5 OS=Homo sapiens OX=9606 GN=RPS5 PE=1 SV=4 9.6 2015.8 - 1.17E+06 - - - 0.2621 - 2.093 0.232 - 293.2 1 2 0 0.0003 10 0 0 0 7.63E+08 8.14E+08 - - - 3.2835 0.9656 221125_WJC_METTL3_EV_vs_WT_F05.09217.09217.2 0.052 14-Jul L.KWLDSDAR.N "sp|P34913|HYES_HUMAN,tr|E5RFU2|E5RFU2_HUMAN,tr|E5RFH6|E5RFH6_HUMAN" 3 989.493 999 61841 9217 2 989.493043 495.7538 Bifunctional epoxide hydrolase 2 OS=Homo sapiens OX=9606 GN=EPHX2 PE=1 SV=2 5.96 2015.9 - 663729 - - - -0.001 - 1.462 0.361 - 300.3 1 1 0 0 8 0 0 0 2.14E+09 0.00E+00 - - - 2.8528 0.9999 221125_WJC_METTL3_EV_vs_WT_F05.09218.09218.2 1.34E-06 20-Oct K.SIDSNPYDTDK[136.11].M "sp|P46459|NSF_HUMAN,tr|I3L0L3|I3L0L3_HUMAN,tr|I3L0N3|I3L0N3_HUMAN" 3 1261.5554 1.56 61842 9218 2 1261.555142 631.785 Vesicle-fusing ATPase OS=Homo sapiens OX=9606 GN=NSF PE=1 SV=3 3.93 2016.1 - 333016 - - - -0.1855 - 1.996 0.595 - 209.5 1 2 0 -0.0002 11 0 0 0 1.81E+07 1.16E+07 - - - 5.3053 0.9773 221125_WJC_METTL3_EV_vs_WT_F05.09219.09219.2 0.0107 20-Sep R.GLLVDR[166.11]PSETK[136.11].T "sp|Q9UKV3|ACINU_HUMAN,tr|G3V3B0|G3V3B0_HUMAN,tr|S4R3H4|S4R3H4_HUMAN,tr|E7EQT4|E7EQT4_HUMAN" 4 1231.6891 3.42 61843 9219 2 1231.697872 616.8518 Apoptotic chromatin condensation inducer in the nucleus OS=Homo sapiens OX=9606 GN=ACIN1 PE=1 SV=2 6.07 2016.2 - 292308 - - - 7.1041 - 2.116 0.332 - 262.6 1 2 0 0.0088 11 0 0 0 1.46E+07 4.26E+06 - - - 3.5181 0.9996 221125_WJC_METTL3_EV_vs_WT_F05.09220.09220.2 4.77E-05 22-Sep R.QAASSLQQASLK[136.11].L "sp|P38646|GRP75_HUMAN,tr|A0A7I2V2S7|A0A7I2V2S7_HUMAN,tr|A0A7I2V2G2|A0A7I2V2G2_HUMAN,tr|A0A7I2V3F7|A0A7I2V3F7_HUMAN,tr|A0A7I2YQB2|A0A7I2YQB2_HUMAN,tr|D6RCD7|D6RCD7_HUMAN" 6 1238.671 0.39 61844 9220 2 1238.673368 620.3428 "Stress-70 protein, mitochondrial OS=Homo sapiens OX=9606 GN=HSPA9 PE=1 SV=2" 8.75 2016.3 - 261396 - - - 1.8996 - 1.9 0.466 - 264.2 1 2 0 0.0024 12 0 0 0 4.58E+05 1.18E+06 - - - 4.171 0.9999 221125_WJC_METTL3_EV_vs_WT_F05.09221.09221.2 9.69E-06 18-Sep K.C[160.03]QVC[160.03]LESEGR[166.11].Y sp|Q9NP73|ALG13_HUMAN 1 1246.531 1.11 61845 9221 2 1246.531802 624.2728 Putative bifunctional UDP-N-acetylglucosamine transferase and deubiquitinase ALG13 OS=Homo sapiens OX=9606 GN=ALG13 PE=1 SV=2 4.53 2016.4 - 127494 - - - 0.6618 - 1.789 0.624 - 281.8 1 2 0 0.0008 10 0 0 0 2.62E+06 2.35E+06 - - - 5.2732 1 221125_WJC_METTL3_EV_vs_WT_F05.09224.09224.3 9.32E-05 Dec-44 R.TLVAVKPDGVQR.R "sp|O00746|NDKM_HUMAN,tr|Q4TT34|Q4TT34_HUMAN,tr|A0A087WVT9|A0A087WVT9_HUMAN,tr|H0Y6J0|H0Y6J0_HUMAN,tr|F2Z2X0|F2Z2X0_HUMAN" 5 1281.7405 1.17 61846 9224 3 1281.741121 428.2541 "Nucleoside diphosphate kinase, mitochondrial OS=Homo sapiens OX=9606 GN=NME4 PE=1 SV=1" 8.41 2016.9 - 3.23E+06 - - - 0.4962 - 1.973 0.502 - 153.6 1 2 0 0.0006 12 0 0 0 2.86E+07 2.45E+07 - - - 6.0203 0.9895 221125_WJC_METTL3_EV_vs_WT_F05.09225.09225.2 5.33E-06 20-Oct K.SNFSNSADDIK[136.11].S sp|P45973|CBX5_HUMAN 1 1204.5451 0.24 61847 9225 2 1205.547531 603.2798 Chromobox protein homolog 5 OS=Homo sapiens OX=9606 GN=CBX5 PE=1 SV=1 4.21 2016.9 - 2.63E+06 - - - 832.1689 - 1.717 0.501 - 331.7 1 2 0 1.0024 11 0 0 0 2.44E+07 1.00E+08 - - - 3.889 0.9997 221125_WJC_METTL3_EV_vs_WT_F05.09226.09226.3 0.0176 Dec-36 R.QAVDVSPLRR.V "sp|P46782|RS5_HUMAN,tr|M0QZN2|M0QZN2_HUMAN,tr|M0R0F0|M0R0F0_HUMAN,tr|M0R0R2|M0R0R2_HUMAN" 4 1139.6411 0.94 61848 9226 3 1139.641964 380.8876 40S ribosomal protein S5 OS=Homo sapiens OX=9606 GN=RPS5 PE=1 SV=4 9.6 2017 - 1.86E+06 - - - 0.7537 - 2.202 0.296 - 288.6 1 2 0 0.0009 10 0 0 0 7.63E+08 8.13E+08 - - - 4.1452 1 221125_WJC_METTL3_EV_vs_WT_F05.09228.09228.2 5.57E-08 20-Nov K.SNFSNSADDIK.S sp|P45973|CBX5_HUMAN 1 1196.5309 0.29 61850 9228 2 1196.53191 599.2727 Chromobox protein homolog 5 OS=Homo sapiens OX=9606 GN=CBX5 PE=1 SV=1 4.21 2017.2 - 810745 - - - 0.8057 - 2.463 0.655 - 449.4 1 2 0 0.001 11 0 0 0 2.44E+07 8.43E+07 - - - 6.317 0.9999 221125_WJC_METTL3_EV_vs_WT_F05.09229.09229.3 0.0125 Nov-40 R.FTAVTAYQNHR.L "sp|O43435|TBX1_HUMAN,sp|O75333|TBX10_HUMAN,tr|A0A3B3IS18|A0A3B3IS18_HUMAN" 3 1306.6418 1 61851 9229 3 1306.642608 436.5546 T-box transcription factor TBX1 OS=Homo sapiens OX=9606 GN=TBX1 PE=1 SV=1 8.75 2017.3 - 467793 - - - 0.5924 - 2.183 0.378 - 154.4 1 2 0 0.0008 11 0 0 0 5.94E+06 5.95E+06 - - - 4.9719 0.9999 221125_WJC_METTL3_EV_vs_WT_F05.09232.09232.2 2.03E-09 13/24 K.TGYGELNGNAGER[166.11].E sp|Q7Z417|NUFP2_HUMAN 1 1346.609 5.7 61854 9232 2 1346.607413 674.3118 Nuclear fragile X mental retardation-interacting protein 2 OS=Homo sapiens OX=9606 GN=NUFIP2 PE=1 SV=1 4.53 2017.7 - 208165 - - - -1.1986 - 2.64 0.563 - 371.9 1 2 0 -0.0016 13 0 0 0 3.18E+07 5.58E+06 - - - 5.6903 0.9975 221125_WJC_METTL3_EV_vs_WT_F05.09238.09238.2 0.0224 18-Sep R.QAVDVSPLR[166.11]R[166.11].V "sp|P46782|RS5_HUMAN,tr|M0QZN2|M0QZN2_HUMAN,tr|M0R0F0|M0R0F0_HUMAN,tr|M0R0R2|M0R0R2_HUMAN" 4 1159.6576 1.01 61858 9238 2 1159.654768 580.8361 40S ribosomal protein S5 OS=Homo sapiens OX=9606 GN=RPS5 PE=1 SV=4 9.6 2018.4 - 1.17E+06 - - - -2.4809 - 1.717 0.272 - 221.3 1 2 0 -0.0029 10 0 0 0 1.94E+08 1.93E+08 - - - 2.558 0.9956 221125_WJC_METTL3_EV_vs_WT_F05.09240.09240.2 0.00537 20-Oct K.LAQYEPPQEEK.R "sp|Q99417|MYCBP_HUMAN,tr|A0A087WV05|A0A087WV05_HUMAN" 2 1330.6405 2.1 61860 9240 2 1330.64361 666.3275 c-Myc-binding protein OS=Homo sapiens OX=9606 GN=MYCBP PE=1 SV=3 4.25 2018.6 - 1.12E+06 - - - 2.3402 - 1.733 0.202 - 303.9 1 2 0 0.0031 11 0 0 0 1.50E+08 7.14E+07 - - - 2.0195 0.9999 221125_WJC_METTL3_EV_vs_WT_F05.09241.09241.3 0.00333 Nov-36 R.IFHELTQTDK[136.11].A "sp|P11586|C1TC_HUMAN,tr|F5H2F4|F5H2F4_HUMAN,tr|V9GZ78|V9GZ78_HUMAN,tr|V9GYY3|V9GYY3_HUMAN,tr|A0A494C1T2|A0A494C1T2_HUMAN" 5 1238.6387 1.63 61861 9241 3 1238.639044 413.8868 "C-1-tetrahydrofolate synthase, cytoplasmic OS=Homo sapiens OX=9606 GN=MTHFD1 PE=1 SV=4" 5.32 2018.7 - 687480 - - - 0.3165 - 2.265 0.36 - 144 1 2 0 0.0004 10 0 0 0 2.08E+08 1.27E+08 - - - 4.9412 0.9963 221125_WJC_METTL3_EV_vs_WT_F05.09242.09242.2 2.4 16-Sep K.DAHLLVESK[136.11].N "sp|P42704|LPPRC_HUMAN,tr|A0A804HI14|A0A804HI14_HUMAN,tr|A0A804HL40|A0A804HL40_HUMAN,tr|A0A804HKJ0|A0A804HKJ0_HUMAN,tr|A0A804HIN4|A0A804HIN4_HUMAN,tr|A0A804HLG8|A0A804HLG8_HUMAN,tr|A0A804HIV5|A0A804HIV5_HUMAN,tr|A0A804HHY9|A0A804HHY9_HUMAN,tr|A0A804HJH8|A0A804HJH8_HUMAN,tr|B8ZZ38|B8ZZ38_HUMAN,tr|A0A804HI40|A0A804HI40_HUMAN,tr|A0A804HJZ1|A0A804HJZ1_HUMAN,tr|C9JCA9|C9JCA9_HUMAN,tr|A0A804HIQ7|A0A804HIQ7_HUMAN,tr|A0A804HK30|A0A804HK30_HUMAN,tr|A0A804HKI2|A0A804HKI2_HUMAN,tr|A0A804HJI0|A0A804HJI0_HUMAN,tr|A0A804HIG4|A0A804HIG4_HUMAN,tr|A0A804HK02|A0A804HK02_HUMAN" 19 1018.5539 1.06 61862 9242 2 1018.552626 510.2842 "Leucine-rich PPR motif-containing protein, mitochondrial OS=Homo sapiens OX=9606 GN=LRPPRC PE=1 SV=3" 5.32 2018.8 - 488062 - - - -1.2115 - 1.85 0.113 - 298.1 2 2 0 -0.0012 9 0 0 0 4.68E+06 4.43E+06 - - - 1.5205 0.9925 221125_WJC_METTL3_EV_vs_WT_F05.09244.09244.2 0.00011 28-Dec R.EEAGGEAAAAAAAER.G sp|O14497|ARI1A_HUMAN 1 1372.6219 2.01 61864 9244 2 1372.631119 687.3182 AT-rich interactive domain-containing protein 1A OS=Homo sapiens OX=9606 GN=ARID1A PE=1 SV=3 4.09 2019.1 - 249838 - - - 6.7265 - 2.278 0.505 - 396.6 1 2 0 0.0092 15 0 0 0 5.47E+06 2.72E+06 - - - 4.7921 0.9995 221125_WJC_METTL3_EV_vs_WT_F05.09246.09246.2 3.09E-05 22-Sep K.AEGEPQEESPLK.S "sp|Q9NYF8|BCLF1_HUMAN,tr|E9PKI6|E9PKI6_HUMAN,tr|A0A1W2PQ43|A0A1W2PQ43_HUMAN,tr|E9PK91|E9PK91_HUMAN,tr|E9PJA7|E9PJA7_HUMAN,tr|E9PK09|E9PK09_HUMAN,tr|E9PQN2|E9PQN2_HUMAN" 7 1312.6147 83.72 61865 9246 2 1312.618231 657.3146 Bcl-2-associated transcription factor 1 OS=Homo sapiens OX=9606 GN=BCLAF1 PE=1 SV=2 4.09 2019.3 - 350638 - - - 2.7083 - 2.016 0.517 - 243 1 2 0 0.0036 12 0 0 0 1.87E+07 2.24E+05 - - - 4.7032 0.9998 221125_WJC_METTL3_EV_vs_WT_F05.09248.09248.2 0.000287 16-Aug K.VDPEIQNVK.A sp|P35908|K22E_HUMAN 1 1040.5502 23.28 61866 9248 2 1040.551066 521.2824 "Keratin, type II cytoskeletal 2 epidermal OS=Homo sapiens OX=9606 GN=KRT2 PE=1 SV=2" 4.37 2019.5 - 2.09E+06 - - - 0.8082 - 1.903 0.463 - 242.3 1 2 0 0.0008 9 0 0 0 6.81E+07 2.93E+06 - - - 4.3219 0.9998 221125_WJC_METTL3_EV_vs_WT_F05.09249.09249.3 0.00166 Oct-36 R.IFHELTQTDK.A "sp|P11586|C1TC_HUMAN,tr|F5H2F4|F5H2F4_HUMAN,tr|V9GZ78|V9GZ78_HUMAN,tr|V9GYY3|V9GYY3_HUMAN,tr|A0A494C1T2|A0A494C1T2_HUMAN" 5 1230.6245 1.62 61867 9249 3 1230.623941 411.2154 "C-1-tetrahydrofolate synthase, cytoplasmic OS=Homo sapiens OX=9606 GN=MTHFD1 PE=1 SV=4" 5.32 2019.6 - 1.67E+06 - - - -0.4152 - 2.093 0.348 - 114.1 1 2 0 -0.0005 10 0 0 0 2.08E+08 1.28E+08 - - - 4.5767 0.9998 221125_WJC_METTL3_EV_vs_WT_F05.09250.09250.2 0.00058 18-Nov R.QAVDVSPLRR.V "sp|P46782|RS5_HUMAN,tr|M0QZN2|M0QZN2_HUMAN,tr|M0R0F0|M0R0F0_HUMAN,tr|M0R0R2|M0R0R2_HUMAN" 4 1139.6411 1.01 61868 9250 2 1139.640395 570.8278 40S ribosomal protein S5 OS=Homo sapiens OX=9606 GN=RPS5 PE=1 SV=4 9.6 2019.6 - 1.45E+06 - - - -0.623 - 1.942 0.417 - 317.3 1 2 0 -0.0007 10 0 0 0 1.94E+08 1.93E+08 - - - 3.9734 0.9904 221125_WJC_METTL3_EV_vs_WT_F05.09252.09252.2 1.3 14-Jul R.R[166.11]ILQSLEK[136.11].M sp|P49790|NU153_HUMAN 1 1003.6145 1.31 61870 9252 2 1003.614156 502.8145 Nuclear pore complex protein Nup153 OS=Homo sapiens OX=9606 GN=NUP153 PE=1 SV=2 8.75 2019.8 - 676380 - - - -0.3428 - 1.504 0.08 - 155.6 3 2 0 -0.0003 8 0 0 0 2.83E+07 2.15E+07 - - - 0.6495 0.9017 221125_WJC_METTL3_EV_vs_WT_F05.09253.09253.2 0.0092 16-Oct R.TK[136.11]DLIIEQR[166.11].F "sp|Q00341|VIGLN_HUMAN,tr|A0A024R4E5|A0A024R4E5_HUMAN,tr|H7BZC3|H7BZC3_HUMAN,tr|H0Y394|H0Y394_HUMAN" 4 1132.6571 0.37 61871 9253 2 1132.653199 567.3358 Vigilin OS=Homo sapiens OX=9606 GN=HDLBP PE=1 SV=2 5.74 2019.9 - 314432 - - - -3.4379 - 1.868 0.154 - 351.7 1 2 1 -0.0039 9 0 0 0 9.54E+05 2.61E+06 - - - 1.985 0.9999 221125_WJC_METTL3_EV_vs_WT_F05.09256.09256.2 4.56E-08 28-Nov R.EEAGGEAAAAAAAER[166.11].G sp|O14497|ARI1A_HUMAN 1 1382.6302 2.01 61874 9256 2 1382.629118 692.3224 AT-rich interactive domain-containing protein 1A OS=Homo sapiens OX=9606 GN=ARID1A PE=1 SV=3 4.09 2020.3 - 148453 - - - -0.7507 - 2.637 0.44 - 396.6 1 2 0 -0.001 15 0 0 0 5.47E+06 2.72E+06 - - - 4.6744 0.9997 221125_WJC_METTL3_EV_vs_WT_F05.09259.09259.2 0.00379 16-Aug K.AQYEEIAQR.S "sp|P48668|K2C6C_HUMAN,sp|Q01546|K22O_HUMAN,sp|P19013|K2C4_HUMAN,sp|P04259|K2C6B_HUMAN,sp|P35908|K22E_HUMAN,sp|P02538|K2C6A_HUMAN" 6 1106.5356 7.12 61876 9259 2 1106.534807 554.2751 "Keratin, type II cytoskeletal 6C OS=Homo sapiens OX=9606 GN=KRT6C PE=1 SV=3" 4.53 2020.8 - 626861 - - - -0.7501 - 1.815 0.405 - 329.7 1 2 0 -0.0008 9 0 0 0 2.21E+07 3.10E+06 - - - 3.7566 0.7903 221125_WJC_METTL3_EV_vs_WT_F05.09261.09261.2 0.591 12-Jun N.KIDSEGR.S "sp|O75762|TRPA1_HUMAN,tr|H0YAW0|H0YAW0_HUMAN" 2 803.4137 1178.66 61877 9261 2 803.412932 402.7141 Transient receptor potential cation channel subfamily A member 1 OS=Homo sapiens OX=9606 GN=TRPA1 PE=1 SV=3 6.07 2021 - 1.31E+07 - - - -0.9945 - 1.339 0.184 - 174.5 1 1 0 -0.0008 7 0 0 0 4.27E+08 3.62E+05 - - - 1.3247 0.9912 221125_WJC_METTL3_EV_vs_WT_F05.09263.09263.2 9.18E-06 13/22 K.K[136.11]AEAGAGSATEF.Q "sp|Q9NQ39|RS10L_HUMAN,sp|P46783|RS10_HUMAN,tr|F6U211|F6U211_HUMAN,tr|A0A1W2PQS6|A0A1W2PQS6_HUMAN,tr|A0A2R8YFH6|A0A2R8YFH6_HUMAN,tr|A0A2R8Y7H1|A0A2R8Y7H1_HUMAN,tr|S4R435|S4R435_HUMAN" 7 1145.5444 0.97 61879 9263 2 1145.544144 573.7795 Putative 40S ribosomal protein S10-like OS=Homo sapiens OX=9606 GN=RPS10P5 PE=5 SV=1 4.53 2021.2 - 1.11E+06 - - - -0.2392 - 2.073 0.481 - 403.7 1 1 0 -0.0003 12 0 0 0 2.28E+07 2.36E+07 - - - 4.5117 0.8546 221125_WJC_METTL3_EV_vs_WT_F05.09264.09264.2 0.369 14-Aug A.VDVSPLR[166.11]R[166.11].V "sp|P46782|RS5_HUMAN,tr|M0QZN2|M0QZN2_HUMAN,tr|M0R0F0|M0R0F0_HUMAN,tr|M0R0R2|M0R0R2_HUMAN" 4 960.562 1.3 61880 9264 2 960.561414 481.2883 40S ribosomal protein S5 OS=Homo sapiens OX=9606 GN=RPS5 PE=1 SV=4 9.57 2021.3 - 1.05E+06 - - - -0.5622 - 1.33 0.242 - 161.8 2 1 0 -0.0005 8 0 0 0 4.76E+07 3.67E+07 - - - 1.5539 0.9989 221125_WJC_METTL3_EV_vs_WT_F05.09265.09265.2 0.16 14-Aug K.EYTEEIER.L "sp|P52732|KIF11_HUMAN,tr|A0A7I2YQY4|A0A7I2YQY4_HUMAN,tr|A0A7I2V3A9|A0A7I2V3A9_HUMAN,tr|A0A7I2V3V3|A0A7I2V3V3_HUMAN" 4 1067.4771 4.38 61881 9265 2 1067.475993 534.7458 Kinesin-like protein KIF11 OS=Homo sapiens OX=9606 GN=KIF11 PE=1 SV=2 4.09 2021.5 - 910085 - - - -1.0548 - 1.469 0.308 - 259 1 2 0 -0.0011 8 0 0 0 3.00E+07 6.85E+06 - - - 2.4754 0.9257 221125_WJC_METTL3_EV_vs_WT_F05.09266.09266.2 0.0249 16-Aug Q.AVDVSPLR[166.11]R[166.11].V "sp|P46782|RS5_HUMAN,tr|M0QZN2|M0QZN2_HUMAN,tr|M0R0F0|M0R0F0_HUMAN,tr|M0R0R2|M0R0R2_HUMAN" 4 1031.5991 1.25 61882 9266 2 1031.598233 516.8068 40S ribosomal protein S5 OS=Homo sapiens OX=9606 GN=RPS5 PE=1 SV=4 9.64 2021.6 - 759764 - - - -0.8094 - 1.499 0.271 - 159.9 1 1 0 -0.0008 9 0 0 0 1.78E+07 1.43E+07 - - - 2.2134 0.9996 221125_WJC_METTL3_EV_vs_WT_F05.09268.09268.2 0.0513 18-Dec R.IFHELTQTDK[136.11].A "sp|P11586|C1TC_HUMAN,tr|F5H2F4|F5H2F4_HUMAN,tr|V9GZ78|V9GZ78_HUMAN,tr|V9GYY3|V9GYY3_HUMAN,tr|A0A494C1T2|A0A494C1T2_HUMAN" 5 1238.6387 1.23 61884 9268 2 1238.635949 620.3266 "C-1-tetrahydrofolate synthase, cytoplasmic OS=Homo sapiens OX=9606 GN=MTHFD1 PE=1 SV=4" 5.32 2021.8 - 611470 - - - -2.1822 - 2.373 0.378 - 556.7 1 2 0 -0.0027 10 0 0 0 4.69E+07 3.81E+07 - - - 4.2442 0.9282 221125_WJC_METTL3_EV_vs_WT_F05.09269.09269.2 0.033 16-Aug Q.AVDVSPLRR.V "sp|P46782|RS5_HUMAN,tr|M0QZN2|M0QZN2_HUMAN,tr|M0R0F0|M0R0F0_HUMAN,tr|M0R0R2|M0R0R2_HUMAN" 4 1011.5825 1.25 61885 9269 2 1011.581428 506.7985 40S ribosomal protein S5 OS=Homo sapiens OX=9606 GN=RPS5 PE=1 SV=4 9.64 2022 - 552026 - - - -1.0874 - 1.523 0.282 - 166.7 1 1 0 -0.0011 9 0 0 0 1.78E+07 1.43E+07 - - - 2.3406 0.9998 221125_WJC_METTL3_EV_vs_WT_F05.09272.09272.2 3.49E-06 22-Dec R.GVDLQENNPASR[166.11].S "sp|P51148|RAB5C_HUMAN,tr|K7EIP6|K7EIP6_HUMAN" 2 1308.6298 1.13 61888 9272 2 1308.632131 655.3222 Ras-related protein Rab-5C OS=Homo sapiens OX=9606 GN=RAB5C PE=1 SV=2 4.37 2022.4 - 367046 - - - 1.8103 - 2.578 0.548 - 636.6 1 2 0 0.0024 12 0 0 0 3.79E+07 3.35E+07 - - - 5.5795 0.9965 221125_WJC_METTL3_EV_vs_WT_F05.09279.09279.2 0.381 12-Jul K.TKPIWTR.N "sp|Q58FF8|H90B2_HUMAN,sp|Q58FG0|HS905_HUMAN,sp|P08238|HS90B_HUMAN,sp|Q58FF6|H90B4_HUMAN,sp|P07900|HS90A_HUMAN,sp|Q14568|HS902_HUMAN" 6 900.5181 0.67 61893 9279 2 900.517219 451.2663 Putative heat shock protein HSP 90-beta 2 OS=Homo sapiens OX=9606 GN=HSP90AB2P PE=1 SV=2 11 2023.2 - 2.47E+06 - - - -1.0194 - 1.31 0.217 - 167.1 1 2 0 -0.0009 7 0 0 0 5.84E+07 8.77E+07 - - - 1.4991 0.9998 221125_WJC_METTL3_EV_vs_WT_F05.09280.09280.2 0.000888 14/22 R.TLVAVKPDGVQR.R "sp|O00746|NDKM_HUMAN,tr|Q4TT34|Q4TT34_HUMAN,tr|A0A087WVT9|A0A087WVT9_HUMAN,tr|H0Y6J0|H0Y6J0_HUMAN,tr|F2Z2X0|F2Z2X0_HUMAN" 5 1281.7405 1.97 61894 9280 2 1281.738974 641.8775 "Nucleoside diphosphate kinase, mitochondrial OS=Homo sapiens OX=9606 GN=NME4 PE=1 SV=1" 8.41 2023.3 - 929646 - - - -1.1789 - 2.383 0.442 - 825 1 2 0 -0.0015 12 0 0 0 8.85E+08 4.49E+08 - - - 4.5899 0.9998 221125_WJC_METTL3_EV_vs_WT_F05.09281.09281.3 0.000173 13/48 K.APLKPYPVSPSDK.V "sp|P41252|SYIC_HUMAN,tr|A0A804HL54|A0A804HL54_HUMAN,tr|A0A804HJN6|A0A804HJN6_HUMAN,tr|A0A804HHW9|A0A804HHW9_HUMAN,tr|A0A0A0MSX9|A0A0A0MSX9_HUMAN,tr|J3KR24|J3KR24_HUMAN,tr|A0A804HJ36|A0A804HJ36_HUMAN" 7 1397.7555 0.97 61895 9281 3 1397.754438 466.9258 "Isoleucine--tRNA ligase, cytoplasmic OS=Homo sapiens OX=9606 GN=IARS1 PE=1 SV=2" 8.54 2023.4 - 899340 - - - -0.7362 - 2.129 0.375 - 169.1 1 2 0 -0.001 13 0 0 0 6.75E+07 6.99E+07 - - - 4.7694 0.9998 221125_WJC_METTL3_EV_vs_WT_F05.09282.09282.2 0.000491 14-Sep R.NQQLDLC[160.03]K.G sp|P78337|PITX1_HUMAN 1 1017.4913 2.42 61896 9282 2 1017.491494 509.7529 Pituitary homeobox 1 OS=Homo sapiens OX=9606 GN=PITX1 PE=1 SV=2 5.83 2023.5 - 402442 - - - 0.1612 - 1.703 0.431 - 420 1 2 0 0.0002 8 0 0 0 4.41E+07 1.82E+07 - - - 3.83 1 221125_WJC_METTL3_EV_vs_WT_F05.09284.09284.2 1.51E-05 24-Nov R.GVEEEEEDGEMRE.- sp|P62306|RUXF_HUMAN 1 1536.5886 1.42 61898 9284 2 1536.589078 769.3016 Small nuclear ribonucleoprotein F OS=Homo sapiens OX=9606 GN=SNRPF PE=1 SV=1 3.88 2023.8 - 154199 - - - 0.313 - 2.605 0.652 - 339.7 1 2 0 0.0005 13 0 0 0 1.18E+08 8.32E+07 - - - 6.3138 0.9996 221125_WJC_METTL3_EV_vs_WT_F05.09286.09286.2 1.85E-06 18-Nov R.IFHELTQTDK.A "sp|P11586|C1TC_HUMAN,tr|F5H2F4|F5H2F4_HUMAN,tr|V9GZ78|V9GZ78_HUMAN,tr|V9GYY3|V9GYY3_HUMAN,tr|A0A494C1T2|A0A494C1T2_HUMAN" 5 1230.6245 1.37 61899 9286 2 1230.62195 616.3195 "C-1-tetrahydrofolate synthase, cytoplasmic OS=Homo sapiens OX=9606 GN=MTHFD1 PE=1 SV=4" 5.32 2024 - 1.99E+06 - - - -2.0331 - 2.248 0.377 - 452.9 1 2 0 -0.0025 10 0 0 0 4.68E+07 3.42E+07 - - - 4.0858 0.9583 221125_WJC_METTL3_EV_vs_WT_F05.09288.09288.2 0.104 14-Sep L.YGLGGSKR.L "sp|P48668|K2C6C_HUMAN,sp|P04259|K2C6B_HUMAN,sp|P02538|K2C6A_HUMAN" 3 836.4505 999 61900 9288 2 836.449879 419.2325 "Keratin, type II cytoskeletal 6C OS=Homo sapiens OX=9606 GN=KRT6C PE=1 SV=3" 9.99 2024.2 - 2.24E+06 - - - -0.6838 - 1.574 0.314 - 317.8 1 1 0 -0.0006 8 0 0 0 5.27E+08 0.00E+00 - - - 2.7281 0.9996 221125_WJC_METTL3_EV_vs_WT_F05.09291.09291.3 0.00602 Dec-36 K.VPQIEVETHK[136.11].V "sp|Q14204|DYHC1_HUMAN,tr|A0A7P0T8N2|A0A7P0T8N2_HUMAN,tr|A0A7P0T9C4|A0A7P0T9C4_HUMAN,tr|A0A7P0TBJ7|A0A7P0TBJ7_HUMAN,tr|A0A804HHY6|A0A804HHY6_HUMAN,tr|A0A7P0T9K2|A0A7P0T9K2_HUMAN,tr|A0A7P0TB64|A0A7P0TB64_HUMAN,tr|A0A2R8Y706|A0A2R8Y706_HUMAN,tr|A0A7P0T916|A0A7P0T916_HUMAN,tr|A0A7P0TB75|A0A7P0TB75_HUMAN,tr|A0A7P0T8W5|A0A7P0T8W5_HUMAN,tr|A0A7P0TAF3|A0A7P0TAF3_HUMAN,tr|A0A7P0T9F1|A0A7P0T9F1_HUMAN,tr|A0A7P0TAW9|A0A7P0TAW9_HUMAN,tr|A0A2R8YGC7|A0A2R8YGC7_HUMAN,tr|A0A7P0TA13|A0A7P0TA13_HUMAN,tr|A0A7P0TAV5|A0A7P0TAV5_HUMAN,tr|A0A7P0T7V5|A0A7P0T7V5_HUMAN,tr|A0A7P0T9R4|A0A7P0T9R4_HUMAN,tr|A0A2R8Y5T0|A0A2R8Y5T0_HUMAN,tr|A0A7P0T990|A0A7P0T990_HUMAN,tr|A0A7P0T942|A0A7P0T942_HUMAN,tr|A0A2R8YFZ7|A0A2R8YFZ7_HUMAN,tr|A0A7P0T825|A0A7P0T825_HUMAN,tr|A0A2R8Y6H2|A0A2R8Y6H2_HUMAN,tr|A0A7P0TAM4|A0A7P0TAM4_HUMAN" 26 1186.6437 0.83 61903 9291 3 1186.642311 396.5552 Cytoplasmic dynein 1 heavy chain 1 OS=Homo sapiens OX=9606 GN=DYNC1H1 PE=1 SV=5 5.4 2024.5 - 1.08E+06 - - - -1.2026 - 2.1 0.305 - 147.8 1 2 0 -0.0014 10 0 0 0 1.55E+07 1.88E+07 - - - 4.1068 0.9484 221125_WJC_METTL3_EV_vs_WT_F05.09297.09297.2 0.0395 18-Sep L.VAVK[136.11]PDGVQR[166.11].R "sp|O00746|NDKM_HUMAN,tr|Q4TT34|Q4TT34_HUMAN,tr|A0A087WVT9|A0A087WVT9_HUMAN,tr|H0Y6J0|H0Y6J0_HUMAN,tr|F2Z2X0|F2Z2X0_HUMAN" 5 1085.6312 2.08 61907 9297 2 1085.630238 543.8229 "Nucleoside diphosphate kinase, mitochondrial OS=Homo sapiens OX=9606 GN=NME4 PE=1 SV=1" 8.72 2025.3 - 2.21E+06 - - - -0.8981 - 1.596 0.303 - 224.8 1 1 0 -0.001 10 0 0 0 7.92E+08 3.80E+08 - - - 2.5836 0.9998 221125_WJC_METTL3_EV_vs_WT_F05.09298.09298.2 0.000203 22-Oct R.TLVAVK[136.11]PDGVQR[166.11].R "sp|O00746|NDKM_HUMAN,tr|Q4TT34|Q4TT34_HUMAN,tr|A0A087WVT9|A0A087WVT9_HUMAN,tr|H0Y6J0|H0Y6J0_HUMAN,tr|F2Z2X0|F2Z2X0_HUMAN" 5 1299.763 1.97 61908 9298 2 1299.76215 650.8888 "Nucleoside diphosphate kinase, mitochondrial OS=Homo sapiens OX=9606 GN=NME4 PE=1 SV=1" 8.41 2025.4 - 2.51E+06 - - - -0.6193 - 2.436 0.425 - 385.2 1 2 0 -0.0008 12 0 0 0 8.85E+08 4.49E+08 - - - 4.5225 1 221125_WJC_METTL3_EV_vs_WT_F05.09300.09300.2 7.34E-08 13/22 R.DPLAADESAPQR.V sp|Q96GA3|LTV1_HUMAN 1 1268.5997 1.42 61910 9300 2 1268.599985 635.3071 Protein LTV1 homolog OS=Homo sapiens OX=9606 GN=LTV1 PE=1 SV=1 4.03 2025.6 - 461760 - - - 0.2294 - 2.94 0.616 - 899.8 1 2 0 0.0003 12 0 0 0 3.25E+07 2.29E+07 - - - 6.4282 0.9995 221125_WJC_METTL3_EV_vs_WT_F05.09301.09301.2 3.79E-07 24-Oct K.SPVESTTEPPAVR[166.11].A "sp|P53992|SC24C_HUMAN,tr|G5EA31|G5EA31_HUMAN" 2 1378.6968 0.36 61911 9301 2 1378.692836 690.3557 Protein transport protein Sec24C OS=Homo sapiens OX=9606 GN=SEC24C PE=1 SV=3 4.53 2025.7 - 231687 - - - -2.8599 - 2.534 0.478 - 307.9 1 2 0 -0.0039 13 0 0 0 1.32E+06 3.69E+06 - - - 4.9566 0.9991 221125_WJC_METTL3_EV_vs_WT_F05.09308.09308.2 0.00277 18-Sep R.EQGNIEEAVR[166.11].L sp|O15294|OGT1_HUMAN 1 1153.5603 2.04 61916 9308 2 1153.558146 577.7874 UDP-N-acetylglucosamine--peptide N-acetylglucosaminyltransferase 110 kDa subunit OS=Homo sapiens OX=9606 GN=OGT PE=1 SV=3 4.25 2026.5 - 765539 - - - -1.8551 - 1.776 0.331 - 442.9 1 2 0 -0.0021 10 0 0 0 2.60E+07 1.28E+07 - - - 3.0883 1 221125_WJC_METTL3_EV_vs_WT_F05.09312.09312.2 1.91E-07 13/24 R.GVEEEEEDGEMR[166.11]E.- sp|P62306|RUXF_HUMAN 1 1546.5969 1.27 61918 9312 2 1546.594504 774.3057 Small nuclear ribonucleoprotein F OS=Homo sapiens OX=9606 GN=SNRPF PE=1 SV=1 3.88 2027 - 1.68E+06 - - - -1.5279 - 2.788 0.701 - 572.3 1 2 0 -0.0024 13 0 0 0 1.18E+08 9.28E+07 - - - 6.8494 0.9941 221125_WJC_METTL3_EV_vs_WT_F05.09313.09313.2 0.0301 22-Sep K.ASSLPSSAPAVK.L sp|Q5VUA4|ZN318_HUMAN 1 1113.603 6.01 61919 9313 2 1113.598298 557.8088 Zinc finger protein 318 OS=Homo sapiens OX=9606 GN=ZNF318 PE=1 SV=2 8.8 2027.1 - 1.19E+06 - - - -4.2125 - 1.589 0.363 - 227.5 1 2 0 -0.0047 12 0 0 0 3.24E+07 5.39E+06 - - - 2.9392 0.985 221125_WJC_METTL3_EV_vs_WT_F05.09314.09314.2 0.000169 14-Aug K.GKVC[160.03]FEMK.V "sp|Q00839|HNRPU_HUMAN,tr|A0A1W2PQL0|A0A1W2PQL0_HUMAN,tr|A0A1W2PPL4|A0A1W2PPL4_HUMAN,tr|A0A1W2PQ74|A0A1W2PQ74_HUMAN,tr|Q5RI18|Q5RI18_HUMAN,tr|A0A1W2PPS1|A0A1W2PPS1_HUMAN,tr|A0A1W2PPH7|A0A1W2PPH7_HUMAN,tr|A0A1W2PP34|A0A1W2PP34_HUMAN,tr|A0A1X7SBS1|A0A1X7SBS1_HUMAN" 9 997.4725 0.88 61920 9314 2 997.471012 499.7435 Heterogeneous nuclear ribonucleoprotein U OS=Homo sapiens OX=9606 GN=HNRNPU PE=1 SV=6 8.2 2027.2 - 1.27E+06 - - - -1.5008 - 1.676 0.256 - 199.4 1 2 1 -0.0015 8 0 0 0 4.50E+07 5.14E+07 - - - 2.4888 0.9974 221125_WJC_METTL3_EV_vs_WT_F05.09317.09317.2 3.18E-05 14-Oct K.GK[136.11]VC[160.03]FEMK[136.11].V "sp|Q00839|HNRPU_HUMAN,tr|A0A1W2PQL0|A0A1W2PQL0_HUMAN,tr|A0A1W2PPL4|A0A1W2PPL4_HUMAN,tr|A0A1W2PQ74|A0A1W2PQ74_HUMAN,tr|Q5RI18|Q5RI18_HUMAN,tr|A0A1W2PPS1|A0A1W2PPS1_HUMAN,tr|A0A1W2PPH7|A0A1W2PPH7_HUMAN,tr|A0A1W2PP34|A0A1W2PP34_HUMAN,tr|A0A1X7SBS1|A0A1X7SBS1_HUMAN" 9 1013.5009 0.88 61921 9317 2 1013.499662 507.7577 Heterogeneous nuclear ribonucleoprotein U OS=Homo sapiens OX=9606 GN=HNRNPU PE=1 SV=6 8.2 2027.6 - 2.07E+06 - - - -1.2304 - 1.849 0.461 - 334.9 1 2 1 -0.0012 8 0 0 0 4.50E+07 5.14E+07 - - - 4.2993 0.9993 221125_WJC_METTL3_EV_vs_WT_F05.09319.09319.2 0.0229 16-Sep K.K[136.11]INELTGIK[136.11].E "sp|P35998|PRS7_HUMAN,tr|C9JX88|C9JX88_HUMAN,tr|C9JLS9|C9JLS9_HUMAN" 3 1030.6357 0.59 61923 9319 2 1030.633875 516.3251 26S proteasome regulatory subunit 7 OS=Homo sapiens OX=9606 GN=PSMC2 PE=1 SV=3 8.59 2027.9 - 833641 - - - -1.8154 - 1.812 0.35 - 271.5 1 2 0 -0.0019 9 0 0 0 5.83E+06 9.82E+06 - - - 3.3452 0.9987 221125_WJC_METTL3_EV_vs_WT_F05.09323.09323.3 0.000559 15/48 K.VVGDVAYDEAK[136.11]ER[166.11].A "sp|P11586|C1TC_HUMAN,tr|F5H2F4|F5H2F4_HUMAN,tr|V9GZ78|V9GZ78_HUMAN,tr|V9GYY3|V9GYY3_HUMAN" 4 1467.7324 0.96 61925 9323 3 1467.729148 490.2514 "C-1-tetrahydrofolate synthase, cytoplasmic OS=Homo sapiens OX=9606 GN=MTHFD1 PE=1 SV=4" 4.32 2028.4 - 762217 - - - -2.245 - 2.576 0.341 - 311.5 1 2 1 -0.0033 13 0 0 0 2.87E+07 3.01E+07 - - - 4.9064 0.977 221125_WJC_METTL3_EV_vs_WT_F05.09325.09325.2 0.00167 20-Dec T.LVAVKPDGVQR.R "sp|O00746|NDKM_HUMAN,tr|Q4TT34|Q4TT34_HUMAN,tr|A0A087WVT9|A0A087WVT9_HUMAN,tr|H0Y6J0|H0Y6J0_HUMAN,tr|F2Z2X0|F2Z2X0_HUMAN" 5 1180.6928 2.19 61927 9325 2 1180.690664 591.3537 "Nucleoside diphosphate kinase, mitochondrial OS=Homo sapiens OX=9606 GN=NME4 PE=1 SV=1" 8.75 2028.6 - 1.14E+06 - - - -1.815 - 2.108 0.404 - 563 1 1 0 -0.0021 11 0 0 0 7.43E+07 3.40E+07 - - - 4.0417 0.9737 221125_WJC_METTL3_EV_vs_WT_F05.09328.09328.2 0.0158 20-Aug T.LVAVK[136.11]PDGVQR[166.11].R "sp|O00746|NDKM_HUMAN,tr|Q4TT34|Q4TT34_HUMAN,tr|A0A087WVT9|A0A087WVT9_HUMAN,tr|H0Y6J0|H0Y6J0_HUMAN,tr|F2Z2X0|F2Z2X0_HUMAN" 5 1198.7153 2.19 61930 9328 2 1198.713991 600.3649 "Nucleoside diphosphate kinase, mitochondrial OS=Homo sapiens OX=9606 GN=NME4 PE=1 SV=1" 8.75 2028.9 - 552339 - - - -1.0728 - 1.781 0.373 - 268 1 1 0 -0.0013 11 0 0 0 7.43E+07 3.40E+07 - - - 3.357 1 221125_WJC_METTL3_EV_vs_WT_F05.09329.09329.2 4.03E-08 15/26 S.LVSGLNSSASEPAK[136.11].E "sp|Q86U44|MTA70_HUMAN,tr|F5H6D8|F5H6D8_HUMAN,tr|H0YFV6|H0YFV6_HUMAN,tr|B4DTN4|B4DTN4_HUMAN" 4 1366.7184 0.01 61931 9329 2 1366.717912 684.3665 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 6 2029.1 - 401923 - - - -0.3271 - 2.768 0.651 - 555.4 1 1 0 -0.0004 14 0 0 0 9.00E+04 1.80E+07 - - - 6.4041 1 221125_WJC_METTL3_EV_vs_WT_F05.09335.09335.2 1.19E-08 28-Dec R.SDSPVPTAPTSGGPK[136.11].P "sp|Q86U44|MTA70_HUMAN,tr|B4E349|B4E349_HUMAN,tr|F5H6D8|F5H6D8_HUMAN,tr|B4DTN4|B4DTN4_HUMAN" 4 1404.6976 0.001 61935 9335 2 1404.700273 703.3561 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 5.55 2029.8 - 665747 - - - 1.8858 - 2.388 0.625 - 279.6 1 1 0 0.0026 15 0 0 0 0.00E+00 1.62E+07 - - - 5.7965 0.9999 221125_WJC_METTL3_EV_vs_WT_F05.09346.09346.3 0.0111 13/44 R.TLVAVKPDGVQR[166.11].R "sp|O00746|NDKM_HUMAN,tr|Q4TT34|Q4TT34_HUMAN,tr|A0A087WVT9|A0A087WVT9_HUMAN,tr|H0Y6J0|H0Y6J0_HUMAN,tr|F2Z2X0|F2Z2X0_HUMAN" 5 1291.7488 - 61942 9346 3 1291.747771 431.5902 "Nucleoside diphosphate kinase, mitochondrial OS=Homo sapiens OX=9606 GN=NME4 PE=1 SV=1" 8.41 2031.1 - 1.77E+06 - - - -0.7618 - 2.165 0.379 - 140 1 2 0 -0.001 12 0 0 0 - - - - - 4.9062 0.9877 221125_WJC_METTL3_EV_vs_WT_F05.09348.09348.2 0.0179 20-Nov M.IASDSHRPEVK.L "sp|Q9NYF8|BCLF1_HUMAN,tr|E9PKI6|E9PKI6_HUMAN,tr|A0A1W2PQ43|A0A1W2PQ43_HUMAN,tr|E9PK91|E9PK91_HUMAN,tr|E9PJA7|E9PJA7_HUMAN,tr|E9PK09|E9PK09_HUMAN,tr|E9PQN2|E9PQN2_HUMAN" 7 1237.6415 5.71 61944 9348 2 1237.639591 619.828 Bcl-2-associated transcription factor 1 OS=Homo sapiens OX=9606 GN=BCLAF1 PE=1 SV=2 6.75 2031.3 - 912072 - - - -1.5416 - 2.492 0.435 - 310.1 1 1 0 -0.0019 11 0 0 0 2.07E+07 3.63E+06 - - - 4.7234 0.9997 221125_WJC_METTL3_EV_vs_WT_F05.09357.09357.2 2.52E-06 22-Oct R.TQPMTAQAASYR.A sp|Q96PK6|RBM14_HUMAN 1 1323.6241 1.63 61951 9357 2 1323.620903 662.8193 RNA-binding protein 14 OS=Homo sapiens OX=9606 GN=RBM14 PE=1 SV=2 8.41 2032.5 - 370857 - - - -2.4418 - 1.908 0.571 - 381.6 1 2 0 -0.0032 12 0 0 0 9.40E+08 5.76E+08 - - - 4.9573 0.9703 221125_WJC_METTL3_EV_vs_WT_F05.09358.09358.2 0.00055 16-Nov A.SDSHRPEVK.L "sp|Q9NYF8|BCLF1_HUMAN,tr|E9PKI6|E9PKI6_HUMAN,tr|A0A1W2PQ43|A0A1W2PQ43_HUMAN,tr|E9PK91|E9PK91_HUMAN,tr|E9PJA7|E9PJA7_HUMAN,tr|E9PK09|E9PK09_HUMAN,tr|E9PQN2|E9PQN2_HUMAN" 7 1053.5203 4.71 61952 9358 2 1053.522809 527.7674 Bcl-2-associated transcription factor 1 OS=Homo sapiens OX=9606 GN=BCLAF1 PE=1 SV=2 6.47 2032.6 - 258353 - - - 2.3607 - 2.085 0.422 - 411.1 1 1 0 0.0025 9 0 0 0 1.08E+06 2.30E+05 - - - 4.2828 0.7826 221125_WJC_METTL3_EV_vs_WT_F05.09359.09359.2 0.273 18-Jul K.SKLPNTVLGK.L "sp|Q9H4M9|EHD1_HUMAN,tr|A0A024R571|A0A024R571_HUMAN" 2 1055.6339 1.45 61953 9359 2 1055.633401 528.8242 EH domain-containing protein 1 OS=Homo sapiens OX=9606 GN=EHD1 PE=1 SV=2 10 2032.7 - 216189 - - - -0.468 - 1.378 0.044 - 142.1 3 2 1 -0.0005 10 0 0 0 5.36E+06 3.71E+06 - - - 0.0477 0.9479 221125_WJC_METTL3_EV_vs_WT_F05.09362.09362.2 0.00293 16-Aug L.AVK[136.11]PDGVQR[166.11].R "sp|Q13232|NDK3_HUMAN,sp|O00746|NDKM_HUMAN,tr|Q4TT34|Q4TT34_HUMAN,tr|H3BRA8|H3BRA8_HUMAN,tr|H3BMQ7|H3BMQ7_HUMAN,tr|H3BPD9|H3BPD9_HUMAN,tr|A0A087WVT9|A0A087WVT9_HUMAN,tr|H0Y6J0|H0Y6J0_HUMAN,tr|F2Z2X0|F2Z2X0_HUMAN" 9 986.5628 2.06 61954 9362 2 986.561124 494.2887 Nucleoside diphosphate kinase 3 OS=Homo sapiens OX=9606 GN=NME3 PE=1 SV=2 8.79 2033.1 - 4.43E+06 - - - -1.6978 - 1.624 0.344 - 129 1 1 0 -0.0017 9 0 0 0 2.40E+08 1.16E+08 - - - 2.9841 0.9804 221125_WJC_METTL3_EV_vs_WT_F05.09363.09363.3 0.00239 Nov-40 T.LVAVKPDGVQR.R "sp|O00746|NDKM_HUMAN,tr|Q4TT34|Q4TT34_HUMAN,tr|A0A087WVT9|A0A087WVT9_HUMAN,tr|H0Y6J0|H0Y6J0_HUMAN,tr|F2Z2X0|F2Z2X0_HUMAN" 5 1180.6928 1.86 61955 9363 3 1180.689359 394.5715 "Nucleoside diphosphate kinase, mitochondrial OS=Homo sapiens OX=9606 GN=NME4 PE=1 SV=1" 8.75 2033.3 - 895282 - - - -2.9203 - 2.023 0.474 - 123.3 1 1 0 -0.0034 11 0 0 0 2.39E+07 1.29E+07 - - - 5.8253 0.9967 221125_WJC_METTL3_EV_vs_WT_F05.09368.09368.2 0.0197 16-Aug R.SQSQLDLC[160.03]K.D "sp|P78411|IRX5_HUMAN,tr|H0YML8|H0YML8_HUMAN" 2 1077.5125 1.53 61960 9368 2 1077.511889 539.7635 Iroquois-class homeodomain protein IRX-5 OS=Homo sapiens OX=9606 GN=IRX5 PE=1 SV=3 5.55 2033.9 - 333452 - - - -0.529 - 1.369 0.199 - 206.9 1 2 0 -0.0006 9 0 0 0 5.03E+06 3.30E+06 - - - 1.4193 0.9997 221125_WJC_METTL3_EV_vs_WT_F05.09371.09371.2 7.97E-05 22-Dec R.TQPMTAQAASYR[166.11].A sp|Q96PK6|RBM14_HUMAN 1 1333.6324 1.76 61961 9371 2 1333.628946 667.8235 RNA-binding protein 14 OS=Homo sapiens OX=9606 GN=RBM14 PE=1 SV=2 8.41 2034.3 - 2.06E+06 - - - -2.5937 - 2.221 0.583 - 389 1 2 0 -0.0035 12 0 0 0 9.38E+08 5.32E+08 - - - 5.4455 0.9996 221125_WJC_METTL3_EV_vs_WT_F05.09374.09374.2 0.000403 22-Nov R.SDAGLESDTAMK[136.11].K sp|Q9NR30|DDX21_HUMAN 1 1231.5482 2.03 61964 9374 2 1231.544557 616.7814 Nucleolar RNA helicase 2 OS=Homo sapiens OX=9606 GN=DDX21 PE=1 SV=5 4.03 2034.6 - 499680 - - - -2.9434 - 2.438 0.521 - 180.2 1 2 0 -0.0036 12 0 0 0 4.74E+06 2.34E+06 - - - 5.2328 1 221125_WJC_METTL3_EV_vs_WT_F05.09380.09380.2 8.25E-07 15/26 R.GFSSGSAVVSGGSR.R sp|P35908|K22E_HUMAN 1 1253.6 12922.7 61968 9380 2 1253.596806 627.8073 "Keratin, type II cytoskeletal 2 epidermal OS=Homo sapiens OX=9606 GN=KRT2 PE=1 SV=2" 9.75 2035.5 - 2.22E+06 - - - -2.571 - 2.859 0.641 - 798.5 1 2 0 -0.0032 14 0 0 0 2.10E+09 1.62E+05 - - - 6.4105 0.9988 221125_WJC_METTL3_EV_vs_WT_F05.09381.09381.2 0.132 20-Nov K.AVQYLSSQDEK.Y sp|Q13835|PKP1_HUMAN 1 1266.6092 1.63 61969 9381 2 1266.605753 634.3119 Plakophilin-1 OS=Homo sapiens OX=9606 GN=PKP1 PE=1 SV=2 4.37 2035.6 - 848368 - - - -2.7183 - 2.301 0.299 - 516.9 1 2 0 -0.0034 11 0 0 0 9.70E+07 5.95E+07 - - - 3.5027 0.9996 221125_WJC_METTL3_EV_vs_WT_F05.09382.09382.2 0.00154 18-Nov K.EDSNLTLQEK.K "sp|P46940|IQGA1_HUMAN,tr|H0YLE8|H0YLE8_HUMAN" 2 1175.567 0.87 61970 9382 2 1175.568447 588.7908 Ras GTPase-activating-like protein IQGAP1 OS=Homo sapiens OX=9606 GN=IQGAP1 PE=1 SV=1 4.14 2035.7 - 1.41E+06 - - - 1.2334 - 2.161 0.352 - 627.5 1 2 0 0.0014 10 0 0 0 2.57E+07 2.94E+07 - - - 3.7913 0.9997 221125_WJC_METTL3_EV_vs_WT_F05.09388.09388.3 0.00844 Dec-36 R.SLEAHMYPEK.L sp|Q01664|TFAP4_HUMAN 1 1203.5594 1.57 61974 9388 3 1203.556888 402.1937 Transcription factor AP-4 OS=Homo sapiens OX=9606 GN=TFAP4 PE=1 SV=2 5.38 2036.5 - 1.26E+06 - - - -2.0946 - 2.175 0.364 - 165.5 1 2 0 -0.0025 10 0 0 0 3.17E+07 2.02E+07 - - - 4.8668 0.9998 221125_WJC_METTL3_EV_vs_WT_F05.09389.09389.2 0.000881 20-Sep K.LNDGSQITYEK[136.11].C "sp|O95831|AIFM1_HUMAN,tr|A0A6Q8PFW2|A0A6Q8PFW2_HUMAN,tr|A0A6Q8PFA7|A0A6Q8PFA7_HUMAN,tr|A0A6Q8PHJ9|A0A6Q8PHJ9_HUMAN,tr|A0A6Q8PFS4|A0A6Q8PFS4_HUMAN,tr|A0A7I2PK44|A0A7I2PK44_HUMAN,tr|A0A6Q8PG15|A0A6Q8PG15_HUMAN,tr|A0A6Q8PFE1|A0A6Q8PFE1_HUMAN,tr|A0A7I2RLJ8|A0A7I2RLJ8_HUMAN,tr|A0A6Q8PFQ8|A0A6Q8PFQ8_HUMAN,tr|A0A6Q8PHC0|A0A6Q8PHC0_HUMAN,tr|A0A6Q8PFM5|A0A6Q8PFM5_HUMAN" 12 1274.6234 1.61 61975 9389 2 1274.620986 638.319 "Apoptosis-inducing factor 1, mitochondrial OS=Homo sapiens OX=9606 GN=AIFM1 PE=1 SV=1" 4.37 2036.6 - 1.15E+06 - - - -1.8908 - 2.447 0.523 - 432.4 1 2 0 -0.0024 11 0 0 0 9.57E+07 5.95E+07 - - - 5.3239 0.9989 221125_WJC_METTL3_EV_vs_WT_F05.09390.09390.2 0.000104 18-Sep K.EDSNLTLQEK[136.11].K "sp|P46940|IQGA1_HUMAN,tr|H0YLE8|H0YLE8_HUMAN" 2 1183.5812 0.87 61976 9390 2 1183.577817 592.7979 Ras GTPase-activating-like protein IQGAP1 OS=Homo sapiens OX=9606 GN=IQGAP1 PE=1 SV=1 4.14 2036.7 - 1.91E+06 - - - -2.8557 - 1.609 0.443 - 262.2 1 2 0 -0.0034 10 0 0 0 2.57E+07 2.94E+07 - - - 3.6395 0.9993 221125_WJC_METTL3_EV_vs_WT_F05.09393.09393.2 0.000116 18-Sep K.STVLQQQYNR.V sp|Q9Y490|TLN1_HUMAN 1 1235.6258 1.77 61979 9393 2 1235.622129 618.8202 Talin-1 OS=Homo sapiens OX=9606 GN=TLN1 PE=1 SV=3 8.46 2037 - 501683 - - - -3.0106 - 2.164 0.433 - 343 1 2 0 -0.0037 10 0 0 0 1.66E+07 9.38E+06 - - - 4.3927 0.9999 221125_WJC_METTL3_EV_vs_WT_F05.09397.09397.3 8.24E-07 14/44 R.TQPMTAQAASYR.A sp|Q96PK6|RBM14_HUMAN 1 1323.6241 1.65 61981 9397 3 1323.61908 442.2153 RNA-binding protein 14 OS=Homo sapiens OX=9606 GN=RBM14 PE=1 SV=2 8.41 2037.5 - 831392 - - - -3.8191 - 2.525 0.532 - 365.7 1 2 0 -0.0051 12 0 0 0 4.81E+07 2.92E+07 - - - 7.0373 0.9983 221125_WJC_METTL3_EV_vs_WT_F05.09398.09398.2 0.000369 18-Oct R.SAQIADLQQK[136.11].L "sp|O95239|KIF4A_HUMAN,sp|Q2VIQ3|KIF4B_HUMAN" 2 1108.5968 0.72 61982 9398 2 1108.59263 555.3057 Chromosome-associated kinesin KIF4A OS=Homo sapiens OX=9606 GN=KIF4A PE=1 SV=3 5.55 2037.7 - 655363 - - - -3.7507 - 1.929 0.415 - 362.6 1 2 0 -0.0042 10 0 0 0 7.54E+06 1.05E+07 - - - 3.9388 0.9996 221125_WJC_METTL3_EV_vs_WT_F05.09399.09399.2 0.000194 18-Nov K.STVLQQQYNR[166.11].V sp|Q9Y490|TLN1_HUMAN 1 1245.6341 16.49 61983 9399 2 1245.632021 623.8243 Talin-1 OS=Homo sapiens OX=9606 GN=TLN1 PE=1 SV=3 8.46 2037.8 - 519615 - - - -1.6843 - 1.995 0.417 - 597.3 1 2 0 -0.0021 10 0 0 0 1.64E+08 9.93E+06 - - - 4.0481 0.9927 221125_WJC_METTL3_EV_vs_WT_F05.09400.09400.2 7.39E-07 15/24 F.AINEAVESGDVGK.T "sp|P46940|IQGA1_HUMAN,tr|H0YLE8|H0YLE8_HUMAN,tr|A0A0J9YXZ5|A0A0J9YXZ5_HUMAN" 3 1287.6307 0.93 61984 9400 2 1287.629561 644.8226 Ras GTPase-activating-like protein IQGAP1 OS=Homo sapiens OX=9606 GN=IQGAP1 PE=1 SV=1 4.14 2037.9 - 629518 - - - -0.8535 - 2.955 0.439 - 823.6 1 1 0 -0.0011 13 0 0 0 7.41E+06 7.99E+06 - - - 5.0639 0.9957 221125_WJC_METTL3_EV_vs_WT_F05.09402.09402.2 0.175 18-Jun R.AEHIPSGPLR.Q "sp|Q9Y520|PRC2C_HUMAN,tr|E7EPN9|E7EPN9_HUMAN" 2 1075.5774 1.1 61986 9402 2 1075.576201 538.796 Protein PRRC2C OS=Homo sapiens OX=9606 GN=PRRC2C PE=1 SV=4 6.79 2038.2 - 365916 - - - -1.1547 - 1.298 0.219 - 121.1 1 2 0 -0.0012 10 0 0 0 2.52E+07 2.29E+07 - - - 1.3862 1 221125_WJC_METTL3_EV_vs_WT_F05.09406.09406.2 2.56E-07 17/26 R.SLLEGEGSSGGGGR.G "sp|P13645|K1C10_HUMAN,tr|A0A1B0GVI3|A0A1B0GVI3_HUMAN" 2 1261.5899 12710.44 61988 9406 2 1261.588542 631.8022 "Keratin, type I cytoskeletal 10 OS=Homo sapiens OX=9606 GN=KRT10 PE=1 SV=6" 4.53 2038.7 - 1.64E+06 - - - -1.0431 - 2.742 0.597 - 981.3 1 2 0 -0.0013 14 0 0 0 6.67E+09 5.25E+05 - - - 5.9813 0.8412 221125_WJC_METTL3_EV_vs_WT_F05.09410.09410.3 0.363 Jun-32 R.LFEYK[136.11]EDSK[136.11].L sp|P00390|GSHR_HUMAN 1 1173.5889 0.99 61992 9410 3 1173.592009 392.2036 "Glutathione reductase, mitochondrial OS=Homo sapiens OX=9606 GN=GSR PE=1 SV=2" 4.68 2039.2 - 454777 - - - 2.6875 - 1.297 0.208 - 38.3 1 2 1 0.0032 9 0 0 0 5.85E+06 5.89E+06 - - - 1.6419 0.9683 221125_WJC_METTL3_EV_vs_WT_F05.09413.09413.2 0.501 18-Jul R.SLYGLGGSKR.L "sp|P48668|K2C6C_HUMAN,sp|P04259|K2C6B_HUMAN,sp|P02538|K2C6A_HUMAN" 3 1036.5665 167.74 61994 9413 2 1036.568528 519.2905 "Keratin, type II cytoskeletal 6C OS=Homo sapiens OX=9606 GN=KRT6C PE=1 SV=3" 9.99 2039.5 - 360237 - - - 1.915 - 1.338 0.069 - 141.1 1 2 0 0.002 10 0 0 0 6.58E+08 3.92E+06 - - - 0.3628 0.9998 221125_WJC_METTL3_EV_vs_WT_F05.09420.09420.2 7.20E-05 13/20 K.SVTVPEAENPR.D "sp|A0A1B0GTU1|ZC11B_HUMAN,sp|O75152|ZC11A_HUMAN,tr|A0A494C0C4|A0A494C0C4_HUMAN" 3 1197.599 0.33 61998 9420 2 1197.598102 599.8068 Zinc finger CCCH domain-containing protein 11B OS=Homo sapiens OX=9606 GN=ZC3H11B PE=4 SV=1 4.53 2040.6 - 639707 - - - -0.7214 - 2.134 0.39 - 570.2 1 2 0 -0.0009 11 0 0 0 1.82E+07 5.47E+07 - - - 3.9718 0.9683 221125_WJC_METTL3_EV_vs_WT_F05.09422.09422.2 0.00386 14-Sep L.YNLGGSKR.L "sp|P13647|K2C5_HUMAN,tr|F8VV57|F8VV57_HUMAN" 2 893.4719 999 62000 9422 2 893.470117 447.7432 "Keratin, type II cytoskeletal 5 OS=Homo sapiens OX=9606 GN=KRT5 PE=1 SV=3" 9.99 2040.8 - 2.21E+06 - - - -2.0124 - 1.712 0.424 - 300.6 1 1 0 -0.0018 8 0 0 0 6.53E+07 0.00E+00 - - - 3.7937 0.9987 221125_WJC_METTL3_EV_vs_WT_F05.09423.09423.3 0.000192 15/56 R.LLTEIHGGAGGPSGR[166.11].A "sp|Q16763|UBE2S_HUMAN,tr|K7EPJ1|K7EPJ1_HUMAN" 2 1430.7505 0.9 62001 9423 3 1430.756443 477.9241 Ubiquitin-conjugating enzyme E2 S OS=Homo sapiens OX=9606 GN=UBE2S PE=1 SV=2 6.75 2040.9 - 561376 - - - 4.1216 - 2.575 0.34 - 296.7 1 2 0 0.0059 15 0 0 0 3.61E+07 4.01E+07 - - - 4.7971 0.9993 221125_WJC_METTL3_EV_vs_WT_F05.09425.09425.2 0.0432 18-Sep K.ILQQIPDHPK.H sp|Q08554|DSC1_HUMAN 1 1187.6663 999 62003 9425 2 1187.667769 594.8404 Desmocollin-1 OS=Homo sapiens OX=9606 GN=DSC1 PE=1 SV=2 6.74 2041.2 - 395656 - - - 1.2722 - 1.981 0.302 - 239.2 1 2 0 0.0015 10 0 0 0 3.55E+07 0.00E+00 - - - 3.1792 0.9999 221125_WJC_METTL3_EV_vs_WT_F05.09429.09429.3 1.13E-05 Nov-44 K.K[136.11]LVIVGDGAC[160.03]GK[136.11].T "sp|P61586|RHOA_HUMAN,sp|P08134|RHOC_HUMAN,tr|E9PLA2|E9PLA2_HUMAN,tr|U3KQA9|U3KQA9_HUMAN,tr|U3KQV3|U3KQV3_HUMAN,tr|E9PQH6|E9PQH6_HUMAN,tr|Q5JR06|Q5JR06_HUMAN,tr|C9JNR4|C9JNR4_HUMAN,tr|A0A7I2V3G1|A0A7I2V3G1_HUMAN,tr|Q5JR08|Q5JR08_HUMAN,tr|C9JX21|C9JX21_HUMAN,tr|Q5JR05|Q5JR05_HUMAN,tr|E9PN11|E9PN11_HUMAN,tr|A0A7I2V5E6|A0A7I2V5E6_HUMAN,tr|C9JRM1|C9JRM1_HUMAN,tr|Q5JR07|Q5JR07_HUMAN,tr|A0A7I2YQV1|A0A7I2YQV1_HUMAN" 17 1231.6929 2.24 62005 9429 3 1231.691929 411.5716 Transforming protein RhoA OS=Homo sapiens OX=9606 GN=RHOA PE=1 SV=1 8.2 2041.7 - 442022 - - - -0.8233 - 2.11 0.458 - 122.3 1 2 0 -0.001 12 0 0 0 8.30E+06 3.70E+06 - - - 5.7157 0.9996 221125_WJC_METTL3_EV_vs_WT_F05.09431.09431.2 0.000702 14-Oct K.HVVFIAQR[166.11].R "sp|P62081|RS7_HUMAN,tr|B5MCP9|B5MCP9_HUMAN,tr|A0A2R8Y623|A0A2R8Y623_HUMAN" 3 978.5639 0.56 62007 9431 2 978.56254 490.2892 40S ribosomal protein S7 OS=Homo sapiens OX=9606 GN=RPS7 PE=1 SV=1 9.76 2041.9 - 514841 - - - -1.3438 - 1.529 0.435 - 396.4 1 2 0 -0.0013 8 0 0 0 1.40E+07 2.51E+07 - - - 3.5341 0.7645 221125_WJC_METTL3_EV_vs_WT_F05.09432.09432.2 0.0105 14-Nov T.FR[166.11]EESPLR[166.11].L "sp|Q9NYF8|BCLF1_HUMAN,tr|E9PKI6|E9PKI6_HUMAN,tr|A0A1W2PQ43|A0A1W2PQ43_HUMAN,tr|E9PK91|E9PK91_HUMAN,tr|E9PJA7|E9PJA7_HUMAN,tr|E9PK09|E9PK09_HUMAN,tr|E9PQN2|E9PQN2_HUMAN" 7 1052.5518 3.26 62008 9432 2 1052.550819 527.2832 Bcl-2-associated transcription factor 1 OS=Homo sapiens OX=9606 GN=BCLAF1 PE=1 SV=2 6.14 2042.1 - 477528 - - - -0.9159 - 1.801 0.332 - 313 1 1 1 -0.001 8 0 0 0 4.66E+07 1.43E+07 - - - 3.2673 0.9989 221125_WJC_METTL3_EV_vs_WT_F05.09433.09433.2 0.0119 22-Nov R.EEEMGEEEEVER[166.11].E "sp|Q14839|CHD4_HUMAN,tr|A0A2U3TZM0|A0A2U3TZM0_HUMAN,tr|A0A2R8Y5M9|A0A2R8Y5M9_HUMAN,tr|A0A2R8Y445|A0A2R8Y445_HUMAN,tr|A0A2R8Y5J0|A0A2R8Y5J0_HUMAN,tr|A0A2R8Y425|A0A2R8Y425_HUMAN,tr|A0A2R8YFK9|A0A2R8YFK9_HUMAN,tr|A0A2R8Y8C1|A0A2R8Y8C1_HUMAN,tr|A0A0C4DGG9|A0A0C4DGG9_HUMAN,tr|A0A2R8YDW2|A0A2R8YDW2_HUMAN,tr|A0A2R8Y5Z7|A0A2R8Y5Z7_HUMAN,tr|F5GWX5|F5GWX5_HUMAN,tr|A0A2R8YER1|A0A2R8YER1_HUMAN,tr|A0A2R8Y521|A0A2R8Y521_HUMAN,tr|A0A2R8YDJ9|A0A2R8YDJ9_HUMAN,tr|A0A2R8Y212|A0A2R8Y212_HUMAN,tr|A0A2R8YE38|A0A2R8YE38_HUMAN" 17 1503.5911 0.46 62009 9433 2 1503.589087 752.8028 Chromodomain-helicase-DNA-binding protein 4 OS=Homo sapiens OX=9606 GN=CHD4 PE=1 SV=2 3.77 2042.2 - 225081 - - - -1.3075 - 2.404 0.172 - 481.1 1 2 0 -0.002 12 0 0 0 1.59E+06 3.43E+06 - - - 2.6187 0.9985 221125_WJC_METTL3_EV_vs_WT_F05.09434.09434.2 0.0465 22-Oct R.EEEMGEEEEVER.E "sp|Q14839|CHD4_HUMAN,tr|A0A2U3TZM0|A0A2U3TZM0_HUMAN,tr|A0A2R8Y5M9|A0A2R8Y5M9_HUMAN,tr|A0A2R8Y445|A0A2R8Y445_HUMAN,tr|A0A2R8Y5J0|A0A2R8Y5J0_HUMAN,tr|A0A2R8Y425|A0A2R8Y425_HUMAN,tr|A0A2R8YFK9|A0A2R8YFK9_HUMAN,tr|A0A2R8Y8C1|A0A2R8Y8C1_HUMAN,tr|A0A0C4DGG9|A0A0C4DGG9_HUMAN,tr|A0A2R8YDW2|A0A2R8YDW2_HUMAN,tr|A0A2R8Y5Z7|A0A2R8Y5Z7_HUMAN,tr|F5GWX5|F5GWX5_HUMAN,tr|A0A2R8YER1|A0A2R8YER1_HUMAN,tr|A0A2R8Y521|A0A2R8Y521_HUMAN,tr|A0A2R8YDJ9|A0A2R8YDJ9_HUMAN,tr|A0A2R8Y212|A0A2R8Y212_HUMAN,tr|A0A2R8YE38|A0A2R8YE38_HUMAN" 17 1493.5828 0.49 62010 9434 2 1493.584062 747.7987 Chromodomain-helicase-DNA-binding protein 4 OS=Homo sapiens OX=9606 GN=CHD4 PE=1 SV=2 3.77 2042.3 - 200125 - - - 0.8563 - 2.228 0.141 - 323.9 1 2 0 0.0013 12 0 0 0 1.59E+06 3.24E+06 - - - 2.1899 0.9823 221125_WJC_METTL3_EV_vs_WT_F05.09440.09440.2 0.109 18-Oct K.STFREESPLR.L "sp|Q9NYF8|BCLF1_HUMAN,tr|E9PKI6|E9PKI6_HUMAN,tr|A0A1W2PQ43|A0A1W2PQ43_HUMAN,tr|E9PK91|E9PK91_HUMAN,tr|E9PJA7|E9PJA7_HUMAN,tr|E9PK09|E9PK09_HUMAN,tr|E9PQN2|E9PQN2_HUMAN" 7 1220.6149 0.04 62014 9440 2 1220.61433 611.3148 Bcl-2-associated transcription factor 1 OS=Homo sapiens OX=9606 GN=BCLAF1 PE=1 SV=2 5.86 2043 - 1.94E+06 - - - -0.5079 - 1.689 0.201 - 150.3 1 2 1 -0.0006 10 0 0 0 1.78E+08 3.96E+09 - - - 1.9884 1 221125_WJC_METTL3_EV_vs_WT_F05.09441.09441.3 1.23E-05 13/40 K.VPSSTVEYLK[136.11]K[136.11].H "sp|Q9H7C9|AAMDC_HUMAN,tr|E9PNP3|E9PNP3_HUMAN,tr|E9PR47|E9PR47_HUMAN,tr|E9PIQ4|E9PIQ4_HUMAN" 4 1265.7202 1.6 62015 9441 3 1265.719016 422.914 Mth938 domain-containing protein OS=Homo sapiens OX=9606 GN=AAMDC PE=1 SV=1 8.47 2043.1 - 530124 - - - -0.9386 - 2.285 0.468 - 210.9 1 2 0 -0.0012 11 0 0 0 2.72E+08 1.70E+08 - - - 6.105 0.83 221125_WJC_METTL3_EV_vs_WT_F05.09442.09442.2 0.5 20-Aug E.EVSAHDALISK[136.11].E sp|A6NLC5|CC070_HUMAN 1 1176.623 0.01 62016 9442 2 1176.621412 589.3188 UPF0524 protein C3orf70 OS=Homo sapiens OX=9606 GN=C3orf70 PE=2 SV=1 5.32 2043.2 - 448762 - - - -1.3513 - 1.683 0.163 - 203.7 1 1 0 -0.0016 11 0 0 0 7.47E+05 8.06E+07 - - - 1.6527 0.9996 221125_WJC_METTL3_EV_vs_WT_F05.09446.09446.3 0.000223 Nov-36 K.STFREESPLR.L "sp|Q9NYF8|BCLF1_HUMAN,tr|E9PKI6|E9PKI6_HUMAN,tr|A0A1W2PQ43|A0A1W2PQ43_HUMAN,tr|E9PK91|E9PK91_HUMAN,tr|E9PJA7|E9PJA7_HUMAN,tr|E9PK09|E9PK09_HUMAN,tr|E9PQN2|E9PQN2_HUMAN" 7 1220.6149 1.8 62018 9446 3 1220.613113 407.8789 Bcl-2-associated transcription factor 1 OS=Homo sapiens OX=9606 GN=BCLAF1 PE=1 SV=2 5.86 2043.8 - 1.36E+07 - - - -1.505 - 2.253 0.429 - 219.5 1 2 1 -0.0018 10 0 0 0 7.48E+08 4.17E+08 - - - 5.6946 0.9999 221125_WJC_METTL3_EV_vs_WT_F05.09447.09447.3 0.00187 18/56 R.LLTEIHGGAGGPSGR.A "sp|Q16763|UBE2S_HUMAN,tr|K7EPJ1|K7EPJ1_HUMAN" 2 1420.7423 0.64 62019 9447 3 1420.741889 474.588 Ubiquitin-conjugating enzyme E2 S OS=Homo sapiens OX=9606 GN=UBE2S PE=1 SV=2 6.75 2043.9 - 857269 - - - -0.2724 - 2.713 0.39 - 414.5 1 2 0 -0.0004 15 0 0 0 2.33E+07 3.66E+07 - - - 5.4923 1 221125_WJC_METTL3_EV_vs_WT_F05.09449.09449.2 1.99E-07 20-Nov K.YEEIDNAPEER[166.11].A sp|P49411|EFTU_HUMAN 1 1373.5975 1.75 62021 9449 2 1373.591119 687.806 "Elongation factor Tu, mitochondrial OS=Homo sapiens OX=9606 GN=TUFM PE=1 SV=2" 3.91 2044.1 - 686009 - - - -4.6156 - 2.324 0.63 - 551 1 2 0 -0.0063 11 0 0 0 2.22E+08 1.27E+08 - - - 5.9735 1 221125_WJC_METTL3_EV_vs_WT_F05.09450.09450.2 1.46E-07 17/26 K.YASETLQAQSEEAR.R sp|Q9ULR0|ISY1_HUMAN 1 1581.7271 1.55 62022 9450 2 1581.726463 791.8708 Pre-mRNA-splicing factor ISY1 homolog OS=Homo sapiens OX=9606 GN=ISY1 PE=1 SV=3 4.25 2044.3 - 685354 - - - -0.3901 - 3.499 0.641 - 1243.3 1 2 0 -0.0006 14 0 0 0 1.30E+07 8.38E+06 - - - 6.9183 1 221125_WJC_METTL3_EV_vs_WT_F05.09453.09453.2 3.96E-06 14/26 K.YASETLQAQSEEAR[166.11].R sp|Q9ULR0|ISY1_HUMAN 1 1591.7353 1.55 62025 9453 2 1591.727681 796.875 Pre-mRNA-splicing factor ISY1 homolog OS=Homo sapiens OX=9606 GN=ISY1 PE=1 SV=3 4.25 2044.6 - 443169 - - - -4.818 - 3.058 0.565 - 703.8 1 2 0 -0.0077 14 0 0 0 1.30E+07 8.38E+06 - - - 6.0166 0.998 221125_WJC_METTL3_EV_vs_WT_F05.09454.09454.2 0.000399 14-Oct K.HFSPEELK.V "sp|P02511|CRYAB_HUMAN,tr|A0A024R3B9|A0A024R3B9_HUMAN,tr|E9PJL7|E9PJL7_HUMAN,tr|E9PNH7|E9PNH7_HUMAN,tr|E9PRA8|E9PRA8_HUMAN" 5 985.4869 999 62026 9454 2 985.484019 493.7507 Alpha-crystallin B chain OS=Homo sapiens OX=9606 GN=CRYAB PE=1 SV=2 5.4 2044.8 - 345337 - - - -2.9194 - 1.677 0.333 - 291.5 1 2 0 -0.0029 8 0 0 0 8.14E+06 0.00E+00 - - - 3.0589 0.9993 221125_WJC_METTL3_EV_vs_WT_F05.09456.09456.3 7.76E-06 Oct-44 R.TLVAVK[136.11]PDGVQR[166.11].R "sp|O00746|NDKM_HUMAN,tr|Q4TT34|Q4TT34_HUMAN,tr|A0A087WVT9|A0A087WVT9_HUMAN,tr|H0Y6J0|H0Y6J0_HUMAN,tr|F2Z2X0|F2Z2X0_HUMAN" 5 1299.763 1.94 62027 9456 3 1299.760745 434.2616 "Nucleoside diphosphate kinase, mitochondrial OS=Homo sapiens OX=9606 GN=NME4 PE=1 SV=1" 8.41 2045 - 4.16E+06 - - - -1.7003 - 1.87 0.326 - 99.3 1 2 0 -0.0022 12 0 0 0 8.07E+09 4.16E+09 - - - 3.909 0.9999 221125_WJC_METTL3_EV_vs_WT_F05.09457.09457.3 0.000214 Nov-36 K.VETFSGVYK[136.11]K[136.11].L "sp|P62081|RS7_HUMAN,tr|A0A2R8Y623|A0A2R8Y623_HUMAN" 2 1172.6412 0.62 62028 9457 3 1172.639532 391.8877 40S ribosomal protein S7 OS=Homo sapiens OX=9606 GN=RPS7 PE=1 SV=1 8.47 2045 - 6.77E+06 - - - -1.4437 - 2.191 0.405 - 214 1 2 0 -0.0017 10 0 0 0 4.15E+08 6.71E+08 - - - 5.3455 0.9998 221125_WJC_METTL3_EV_vs_WT_F05.09459.09459.2 0.000703 18-Oct R.TIVEEVQDGK.V "sp|Q04695|K1C17_HUMAN,tr|F5GWP8|F5GWP8_HUMAN" 2 1116.5663 147.96 62030 9459 2 1116.564705 559.2904 "Keratin, type I cytoskeletal 17 OS=Homo sapiens OX=9606 GN=KRT17 PE=1 SV=2" 4.14 2045.1 - 1.79E+06 - - - -1.4007 - 1.932 0.51 - 244.3 1 2 0 -0.0016 10 0 0 0 5.73E+07 3.87E+05 - - - 4.6456 0.9992 221125_WJC_METTL3_EV_vs_WT_F05.09460.09460.2 0.0791 16-Nov R.R[166.11]LEVLDSTK[136.11].S "sp|P0C7P4|UCRIL_HUMAN,sp|P47985|UCRI_HUMAN" 2 1077.6149 1.45 62031 9460 2 1077.613298 539.8147 Putative cytochrome b-c1 complex subunit Rieske-like protein 1 OS=Homo sapiens OX=9606 GN=UQCRFS1P1 PE=5 SV=1 6.07 2045.2 - 1.41E+06 - - - -1.481 - 2.052 0.254 - 523.7 1 2 0 -0.0016 9 0 0 0 6.58E+07 4.54E+07 - - - 2.9961 0.9998 221125_WJC_METTL3_EV_vs_WT_F05.09461.09461.2 0.000583 22-Nov K.VIQIATSSSTAK.N "sp|Q7L2E3|DHX30_HUMAN,tr|H7BXY3|H7BXY3_HUMAN" 2 1204.6663 1.34 62032 9461 2 1204.665157 603.3404 ATP-dependent RNA helicase DHX30 OS=Homo sapiens OX=9606 GN=DHX30 PE=1 SV=1 8.72 2045.3 - 1.16E+06 - - - -0.9629 - 2.176 0.442 - 390.2 1 2 0 -0.0012 12 0 0 0 2.65E+07 1.97E+07 - - - 4.351 0.9998 221125_WJC_METTL3_EV_vs_WT_F05.09462.09462.2 0.000999 18-Oct K.VETFSGVYK[136.11]K[136.11].L "sp|P62081|RS7_HUMAN,tr|A0A2R8Y623|A0A2R8Y623_HUMAN" 2 1172.6412 0.69 62033 9462 2 1172.641735 587.3279 40S ribosomal protein S7 OS=Homo sapiens OX=9606 GN=RPS7 PE=1 SV=1 8.47 2045.5 - 992756 - - - 0.4349 - 2.247 0.415 - 435.5 1 2 0 0.0005 10 0 0 0 7.11E+07 1.04E+08 - - - 4.3659 0.9989 221125_WJC_METTL3_EV_vs_WT_F05.09463.09463.2 0.000394 18-Jul R.DYLEDQQGGR.E "sp|P37268|FDFT_HUMAN,tr|A0A1W2PQ47|A0A1W2PQ47_HUMAN,tr|E9PNM1|E9PNM1_HUMAN" 3 1179.5156 0.9 62034 9463 2 1179.515885 590.7651 Squalene synthase OS=Homo sapiens OX=9606 GN=FDFT1 PE=1 SV=1 4.03 2045.6 - 626570 - - - 0.2162 - 1.575 0.275 - 157 1 2 0 0.0003 10 0 0 0 7.12E+06 7.95E+06 - - - 2.34 0.9999 221125_WJC_METTL3_EV_vs_WT_F05.09466.09466.2 8.08E-05 16-Sep K.VTMQNLNDR.L "sp|P13645|K1C10_HUMAN,sp|Q7Z3Z0|K1C25_HUMAN,sp|Q7Z3Y9|K1C26_HUMAN,sp|P02533|K1C14_HUMAN,sp|Q7Z3Y8|K1C27_HUMAN,sp|P08779|K1C16_HUMAN,sp|Q7Z3Y7|K1C28_HUMAN,tr|A0A1B0GVI3|A0A1B0GVI3_HUMAN" 8 1089.5237 344.15 62035 9466 2 1089.522284 545.7691 "Keratin, type I cytoskeletal 10 OS=Homo sapiens OX=9606 GN=KRT10 PE=1 SV=6" 5.81 2046 - 1.05E+07 - - - -1.2923 - 2.034 0.548 - 504.5 1 2 0 -0.0014 9 0 0 0 6.77E+08 1.97E+06 - - - 5.1422 0.9998 221125_WJC_METTL3_EV_vs_WT_F05.09467.09467.2 0.0225 18-Sep R.SLYNLGGSKR.L "sp|P13647|K2C5_HUMAN,tr|F8VV57|F8VV57_HUMAN" 2 1093.588 133.76 62036 9467 2 1093.58732 547.8013 "Keratin, type II cytoskeletal 5 OS=Homo sapiens OX=9606 GN=KRT5 PE=1 SV=3" 9.99 2046.1 - 4.72E+06 - - - -0.6282 - 1.976 0.438 - 306 1 2 0 -0.0007 10 0 0 0 8.68E+07 6.49E+05 - - - 4.1769 0.9999 221125_WJC_METTL3_EV_vs_WT_F05.09468.09468.2 0.00174 20-Nov K.YEEIDNAPEER.A sp|P49411|EFTU_HUMAN 1 1363.5892 1.75 62037 9468 2 1363.588395 682.8019 "Elongation factor Tu, mitochondrial OS=Homo sapiens OX=9606 GN=TUFM PE=1 SV=2" 3.91 2046.1 - 4.76E+06 - - - -0.5823 - 2.313 0.505 - 564.7 1 2 0 -0.0008 11 0 0 0 2.22E+08 1.27E+08 - - - 5.0391 1 221125_WJC_METTL3_EV_vs_WT_F05.09469.09469.3 0.000166 Nov-40 K.VPSSTVEYLKK.H "sp|Q9H7C9|AAMDC_HUMAN,tr|E9PNP3|E9PNP3_HUMAN,tr|E9PR47|E9PR47_HUMAN,tr|E9PIQ4|E9PIQ4_HUMAN" 4 1249.6918 1.59 62038 9469 3 1249.690503 417.5712 Mth938 domain-containing protein OS=Homo sapiens OX=9606 GN=AAMDC PE=1 SV=1 8.47 2046.2 - 2.89E+06 - - - -1.0411 - 2.421 0.466 - 179.5 1 2 0 -0.0013 11 0 0 0 2.72E+08 1.71E+08 - - - 6.2469 0.9985 221125_WJC_METTL3_EV_vs_WT_F05.09470.09470.2 0.00203 16-Nov R.RLEVLDSTK.S "sp|P0C7P4|UCRIL_HUMAN,sp|P47985|UCRI_HUMAN" 2 1059.5924 1.44 62039 9470 2 1059.592963 530.8035 Putative cytochrome b-c1 complex subunit Rieske-like protein 1 OS=Homo sapiens OX=9606 GN=UQCRFS1P1 PE=5 SV=1 6.07 2046.3 - 1.63E+06 - - - 0.5087 - 1.822 0.176 - 432.2 1 2 0 0.0005 9 0 0 0 6.58E+07 4.56E+07 - - - 2.0764 0.9996 221125_WJC_METTL3_EV_vs_WT_F05.09473.09473.2 0.0396 18-Oct K.VETFSGVYKK.L "sp|P62081|RS7_HUMAN,tr|A0A2R8Y623|A0A2R8Y623_HUMAN" 2 1156.6128 0.69 62042 9473 2 1156.610978 579.3137 40S ribosomal protein S7 OS=Homo sapiens OX=9606 GN=RPS7 PE=1 SV=1 8.47 2046.6 - 809238 - - - -1.5969 - 2.021 0.368 - 374.4 1 2 0 -0.0018 10 0 0 0 7.08E+07 1.02E+08 - - - 3.7224 0.9999 221125_WJC_METTL3_EV_vs_WT_F05.09474.09474.3 0.000215 14/52 K.IGSVAPDTINNHVK.T sp|Q9UHY1|NRBP_HUMAN 1 1463.7732 1.72 62043 9474 3 1463.771823 488.9317 Nuclear receptor-binding protein OS=Homo sapiens OX=9606 GN=NRBP1 PE=1 SV=1 6.74 2046.7 - 715742 - - - -0.9694 - 2.645 0.373 - 334.8 1 2 0 -0.0014 14 0 0 0 1.42E+07 8.26E+06 - - - 5.2831 0.9986 221125_WJC_METTL3_EV_vs_WT_F05.09477.09477.3 0.0127 Dec-44 R.TLVAVKPDGVQR.R "sp|O00746|NDKM_HUMAN,tr|Q4TT34|Q4TT34_HUMAN,tr|A0A087WVT9|A0A087WVT9_HUMAN,tr|H0Y6J0|H0Y6J0_HUMAN,tr|F2Z2X0|F2Z2X0_HUMAN" 5 1281.7405 1.94 62044 9477 3 1281.736225 428.2541 "Nucleoside diphosphate kinase, mitochondrial OS=Homo sapiens OX=9606 GN=NME4 PE=1 SV=1" 8.41 2047.1 - 2.84E+06 - - - -3.3236 - 2.02 0.339 - 181.2 1 2 0 -0.0043 12 0 0 0 8.08E+09 4.17E+09 - - - 4.2672 0.9997 221125_WJC_METTL3_EV_vs_WT_F05.09478.09478.3 0.0302 13/44 K.VHTTAADGLYPR.V sp|P0CG40|SP9_HUMAN 1 1299.6571 1.53 62045 9478 3 1299.654956 434.2263 Transcription factor Sp9 OS=Homo sapiens OX=9606 GN=SP9 PE=3 SV=1 6.71 2047.2 - 3.71E+06 - - - -1.6874 - 2.126 0.363 - 256.5 1 2 0 -0.0022 12 0 0 0 7.10E+07 4.65E+07 - - - 4.6771 0.9995 221125_WJC_METTL3_EV_vs_WT_F05.09479.09479.2 4.92E-05 13/22 K.VIQIATSSSTAK[136.11].N "sp|Q7L2E3|DHX30_HUMAN,tr|H7BXY3|H7BXY3_HUMAN" 2 1212.6805 1.34 62046 9479 2 1212.67886 607.3475 ATP-dependent RNA helicase DHX30 OS=Homo sapiens OX=9606 GN=DHX30 PE=1 SV=1 8.72 2047.3 - 1.49E+06 - - - -1.3664 - 2.364 0.298 - 638.6 1 2 0 -0.0017 12 0 0 0 2.65E+07 1.97E+07 - - - 3.5052 0.9925 221125_WJC_METTL3_EV_vs_WT_F05.09486.09486.2 0.00507 22-Aug K.VHTTAADGLYPR.V sp|P0CG40|SP9_HUMAN 1 1299.6571 2.18 62051 9486 2 1299.651992 650.8359 Transcription factor Sp9 OS=Homo sapiens OX=9606 GN=SP9 PE=3 SV=1 6.71 2048.2 - 1.08E+06 - - - -3.968 - 1.501 0.329 - 167.1 1 2 0 -0.0052 12 0 0 0 1.58E+07 7.22E+06 - - - 2.538 0.9993 221125_WJC_METTL3_EV_vs_WT_F05.09487.09487.2 0.000294 22-Oct K.VHTTAADGLYPR[166.11].V sp|P0CG40|SP9_HUMAN 1 1309.6654 2.18 62052 9487 2 1309.661978 655.84 Transcription factor Sp9 OS=Homo sapiens OX=9606 GN=SP9 PE=3 SV=1 6.71 2048.3 - 608778 - - - -2.6274 - 1.878 0.442 - 304.5 1 2 0 -0.0034 12 0 0 0 1.58E+07 7.22E+06 - - - 3.9627 0.9988 221125_WJC_METTL3_EV_vs_WT_F05.09491.09491.3 0.283 13/36 K.STFR[166.11]EESPLR[166.11].L "sp|Q9NYF8|BCLF1_HUMAN,tr|E9PKI6|E9PKI6_HUMAN,tr|A0A1W2PQ43|A0A1W2PQ43_HUMAN,tr|E9PK91|E9PK91_HUMAN,tr|E9PJA7|E9PJA7_HUMAN,tr|E9PK09|E9PK09_HUMAN,tr|E9PQN2|E9PQN2_HUMAN" 7 1240.6315 1.8 62054 9491 3 1240.628789 414.5511 Bcl-2-associated transcription factor 1 OS=Homo sapiens OX=9606 GN=BCLAF1 PE=1 SV=2 5.86 2048.9 - 1.15E+07 - - - -2.1771 - 2.314 0.358 - 322 1 2 1 -0.0027 10 0 0 0 7.47E+08 4.16E+08 - - - 4.9808 0.9992 221125_WJC_METTL3_EV_vs_WT_F05.09492.09492.2 0.0335 18-Aug K.GLEEITVHNK.D "sp|P52732|KIF11_HUMAN,tr|A0A7I2YQY4|A0A7I2YQY4_HUMAN,tr|A0A7I2V3A9|A0A7I2V3A9_HUMAN,tr|A0A7I2V3V3|A0A7I2V3V3_HUMAN" 4 1138.5982 8.54 62055 9492 2 1138.599463 570.3064 Kinesin-like protein KIF11 OS=Homo sapiens OX=9606 GN=KIF11 PE=1 SV=2 5.4 2049 - 1.51E+06 - - - 1.0759 - 1.847 0.293 - 217 1 2 0 0.0012 10 0 0 0 2.05E+07 2.40E+06 - - - 2.9174 0.9997 221125_WJC_METTL3_EV_vs_WT_F05.09493.09493.2 0.0354 20-Oct K.GHAVGDIPGVR[166.11].F "sp|P62266|RS23_HUMAN,tr|D6RD47|D6RD47_HUMAN" 2 1086.581 0.88 62056 9493 2 1086.579961 544.2978 40S ribosomal protein S23 OS=Homo sapiens OX=9606 GN=RPS23 PE=1 SV=3 6.74 2049 - 1.67E+06 - - - -0.9203 - 1.96 0.392 - 371.2 1 2 0 -0.001 11 0 0 0 5.72E+07 6.47E+07 - - - 3.7565 0.996 221125_WJC_METTL3_EV_vs_WT_F05.09495.09495.3 0.081 Sep-36 K.GLEEITVHNK[136.11].D "sp|P52732|KIF11_HUMAN,tr|A0A7I2YQY4|A0A7I2YQY4_HUMAN,tr|A0A7I2V3A9|A0A7I2V3A9_HUMAN,tr|A0A7I2V3V3|A0A7I2V3V3_HUMAN" 4 1146.6124 2.58 62058 9495 3 1146.60941 383.2114 Kinesin-like protein KIF11 OS=Homo sapiens OX=9606 GN=KIF11 PE=1 SV=2 5.4 2049.3 - 1.14E+06 - - - -2.6408 - 1.77 0.257 - 75 1 2 0 -0.003 10 0 0 0 6.79E+07 2.64E+07 - - - 3.072 1 221125_WJC_METTL3_EV_vs_WT_F05.09497.09497.2 1.25E-06 22-Oct K.ILC[160.03]EQC[160.03]MTSNQK[136.11].K "sp|Q8WXI9|P66B_HUMAN,tr|A0A0U1RRM1|A0A0U1RRM1_HUMAN,tr|A0A0U1RR30|A0A0U1RR30_HUMAN" 3 1518.672 1.65 62060 9497 2 1518.672096 760.3433 Transcriptional repressor p66-beta OS=Homo sapiens OX=9606 GN=GATAD2B PE=1 SV=1 5.99 2049.5 - 731826 - - - 0.05 - 2.163 0.64 - 316.5 1 2 0 0.0001 12 0 0 0 9.87E+07 5.99E+07 - - - 5.798 1 221125_WJC_METTL3_EV_vs_WT_F05.09498.09498.2 3.38E-09 13/22 K.ILC[160.03]EQC[160.03]MTSNQK.K "sp|Q8WXI9|P66B_HUMAN,tr|A0A0U1RRM1|A0A0U1RRM1_HUMAN,tr|A0A0U1RR30|A0A0U1RR30_HUMAN" 3 1510.6578 1.65 62061 9498 2 1510.657061 756.3362 Transcriptional repressor p66-beta OS=Homo sapiens OX=9606 GN=GATAD2B PE=1 SV=1 5.99 2049.6 - 659269 - - - -0.5024 - 2.506 0.627 - 665.4 1 2 0 -0.0008 12 0 0 0 9.87E+07 5.99E+07 - - - 6.089 0.9997 221125_WJC_METTL3_EV_vs_WT_F05.09499.09499.2 0.000735 16-Jul K.TC[160.03]SNVNWAR.R sp|O95218|ZRAB2_HUMAN 1 1106.4927 0.91 62062 9499 2 1106.491292 554.2536 Zinc finger Ran-binding domain-containing protein 2 OS=Homo sapiens OX=9606 GN=ZRANB2 PE=1 SV=2 7.91 2049.8 - 511699 - - - -1.2969 - 1.605 0.458 - 174.4 1 2 0 -0.0014 9 0 0 0 1.01E+07 1.12E+07 - - - 3.7921 0.9939 221125_WJC_METTL3_EV_vs_WT_F05.09500.09500.2 8.35E-06 18-Dec V.PSSTVEYLKK.H "sp|Q9H7C9|AAMDC_HUMAN,tr|E9PNP3|E9PNP3_HUMAN,tr|E9PR47|E9PR47_HUMAN,tr|E9PIQ4|E9PIQ4_HUMAN" 4 1150.6234 29.71 62063 9500 2 1150.623918 576.319 Mth938 domain-containing protein OS=Homo sapiens OX=9606 GN=AAMDC PE=1 SV=1 8.9 2049.9 - 489078 - - - 0.4589 - 2.43 0.52 - 364.6 1 1 0 0.0005 10 0 0 0 9.84E+06 3.31E+05 - - - 5.3599 0.9998 221125_WJC_METTL3_EV_vs_WT_F05.09503.09503.3 0.000868 Nov-40 R.VEIIANDQGNR[166.11].L "sp|P11021|BIP_HUMAN,sp|P48741|HSP77_HUMAN,sp|P54652|HSP72_HUMAN,sp|P0DMV8|HS71A_HUMAN,sp|P34931|HS71L_HUMAN,sp|P11142|HSP7C_HUMAN,sp|P0DMV9|HS71B_HUMAN,sp|P17066|HSP76_HUMAN,tr|E9PQQ4|E9PQQ4_HUMAN,tr|E9PNE6|E9PNE6_HUMAN,tr|E9PKE3|E9PKE3_HUMAN,tr|A0A7P0TB36|A0A7P0TB36_HUMAN,tr|E9PLF4|E9PLF4_HUMAN,tr|A0A7P0TAI0|A0A7P0TAI0_HUMAN,tr|Q53FA3|Q53FA3_HUMAN,tr|E9PI65|E9PI65_HUMAN,tr|E9PK54|E9PK54_HUMAN,tr|E9PN25|E9PN25_HUMAN,tr|E9PPY6|E9PPY6_HUMAN,tr|E9PQK7|E9PQK7_HUMAN,tr|A0A0G2JIW1|A0A0G2JIW1_HUMAN" 21 1237.629 0.17 62064 9503 3 1237.626517 413.5503 Endoplasmic reticulum chaperone BiP OS=Homo sapiens OX=9606 GN=HSPA5 PE=1 SV=2 4.37 2050.3 - 1.49E+07 - - - -2.0337 - 2.028 0.392 - 242.9 1 2 0 -0.0025 11 0 0 0 1.96E+08 1.14E+09 - - - 4.9183 0.9995 221125_WJC_METTL3_EV_vs_WT_F05.09504.09504.2 0.00061 14-Oct K.GFHFADSK.Q "sp|Q5JSZ5|PRC2B_HUMAN,tr|A0A804HKU3|A0A804HKU3_HUMAN,tr|A0A804HJR4|A0A804HJR4_HUMAN" 3 907.4188 2 62065 9504 2 907.416713 454.7167 Protein PRRC2B OS=Homo sapiens OX=9606 GN=PRRC2B PE=1 SV=2 6.74 2050.4 - 1.33E+06 - - - -2.3187 - 1.892 0.444 - 252.2 1 2 0 -0.0021 8 0 0 0 3.07E+07 1.54E+07 - - - 4.2428 0.9944 221125_WJC_METTL3_EV_vs_WT_F05.09505.09505.2 0.0325 22-Dec R.LQDVSGQLNSTK[136.11].K "sp|P25440|BRD2_HUMAN,tr|H0Y6K2|H0Y6K2_HUMAN,tr|A0A0G2JK44|A0A0G2JK44_HUMAN,tr|A0A140T9E9|A0A140T9E9_HUMAN,tr|A0A0G2JHN8|A0A0G2JHN8_HUMAN,tr|A0A140T9I1|A0A140T9I1_HUMAN" 6 1296.6765 0.72 62066 9505 2 1296.671672 649.3455 Bromodomain-containing protein 2 OS=Homo sapiens OX=9606 GN=BRD2 PE=1 SV=2 5.84 2050.6 - 1.08E+06 - - - -3.7187 - 1.907 0.258 - 437.9 1 2 0 -0.0048 12 0 0 0 1.02E+07 1.42E+07 - - - 2.6436 0.9598 221125_WJC_METTL3_EV_vs_WT_F05.09506.09506.2 0.00613 16-Oct E.IIANDQGNR[166.11].L "sp|P11021|BIP_HUMAN,sp|P48741|HSP77_HUMAN,sp|P54652|HSP72_HUMAN,sp|P0DMV8|HS71A_HUMAN,sp|P34931|HS71L_HUMAN,sp|P11142|HSP7C_HUMAN,sp|P0DMV9|HS71B_HUMAN,sp|P17066|HSP76_HUMAN,tr|E9PQQ4|E9PQQ4_HUMAN,tr|E9PNE6|E9PNE6_HUMAN,tr|E9PKE3|E9PKE3_HUMAN,tr|A0A7P0TB36|A0A7P0TB36_HUMAN,tr|E9PLF4|E9PLF4_HUMAN,tr|A0A7P0TAI0|A0A7P0TAI0_HUMAN,tr|Q53FA3|Q53FA3_HUMAN,tr|E9PI65|E9PI65_HUMAN,tr|E9PK54|E9PK54_HUMAN,tr|E9PN25|E9PN25_HUMAN,tr|E9PPY6|E9PPY6_HUMAN,tr|E9PQK7|E9PQK7_HUMAN,tr|A0A0G2JIW1|A0A0G2JIW1_HUMAN" 21 1009.518 0.14 62067 9506 2 1009.515815 505.7663 Endoplasmic reticulum chaperone BiP OS=Homo sapiens OX=9606 GN=HSPA5 PE=1 SV=2 5.84 2050.7 - 937716 - - - -2.1911 - 1.79 0.396 - 228.2 1 1 0 -0.0022 9 0 0 0 6.27E+06 4.61E+07 - - - 3.6495 0.9999 221125_WJC_METTL3_EV_vs_WT_F05.09515.09515.2 2.42E-05 14/18 R.YPDGIISK[136.11]PK[136.11].N sp|Q86U44|MTA70_HUMAN 1 1132.6463 0.001 62073 9515 2 1132.646474 567.3304 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 8.5 2051.7 - 1.58E+06 - - - 0.1448 - 2.188 0.506 - 658.9 1 2 0 0.0002 10 0 0 0 0.00E+00 1.29E+08 - - - 4.9638 1 221125_WJC_METTL3_EV_vs_WT_F05.09517.09517.2 2.36E-05 20-Nov K.YTAC[160.03]LC[160.03]DDNPK.T sp|P12273|PIP_HUMAN 1 1355.5486 999 62075 9517 2 1355.547855 678.7816 Prolactin-inducible protein OS=Homo sapiens OX=9606 GN=PIP PE=1 SV=1 4.21 2052 - 880263 - - - -0.54 - 1.989 0.681 - 442.6 1 2 0 -0.0007 11 0 0 0 7.91E+08 0.00E+00 - - - 5.9308 0.9939 221125_WJC_METTL3_EV_vs_WT_F05.09522.09522.2 2.63E-05 20-Dec N.VQDAIADAEQR.G sp|P35908|K22E_HUMAN 1 1214.5891 15.97 62077 9522 2 1214.589621 608.3018 "Keratin, type II cytoskeletal 2 epidermal OS=Homo sapiens OX=9606 GN=KRT2 PE=1 SV=2" 4.03 2052.7 - 562585 - - - 0.4051 - 2.422 0.524 - 804.6 1 1 0 0.0005 11 0 0 0 1.00E+07 6.28E+05 - - - 5.3041 0.9958 221125_WJC_METTL3_EV_vs_WT_F05.09529.09529.2 7.59E-05 20-Nov K.VPSSTVEYLKK.H "sp|Q9H7C9|AAMDC_HUMAN,tr|E9PNP3|E9PNP3_HUMAN,tr|E9PR47|E9PR47_HUMAN,tr|E9PIQ4|E9PIQ4_HUMAN" 4 1249.6918 2.52 62081 9529 2 1249.685205 625.8532 Mth938 domain-containing protein OS=Homo sapiens OX=9606 GN=AAMDC PE=1 SV=1 8.47 2053.6 - 701650 - - - -5.2805 - 1.975 0.455 - 332.3 1 2 0 -0.0066 11 0 0 0 3.07E+07 1.22E+07 - - - 4.2407 0.9999 221125_WJC_METTL3_EV_vs_WT_F05.09531.09531.2 6.21E-07 13/22 R.QINVSTDDSEVK[136.11].A sp|O43172|PRP4_HUMAN 1 1341.6503 3.35 62082 9531 2 1341.650665 671.8324 U4\U6 small nuclear ribonucleoprotein Prp4 OS=Homo sapiens OX=9606 GN=PRPF4 PE=1 SV=2 4.03 2053.8 - 1.85E+06 - - - 0.243 - 2.385 0.551 - 629.4 1 2 0 0.0003 12 0 0 0 7.75E+08 2.31E+08 - - - 5.3976 0.9995 221125_WJC_METTL3_EV_vs_WT_F05.09537.09537.3 0.0156 13/44 K.LSSAENDRDILR.R "sp|Q15643|TRIPB_HUMAN,tr|H0YJ97|H0YJ97_HUMAN" 2 1387.7056 1.33 62086 9537 3 1387.702857 463.5758 Thyroid receptor-interacting protein 11 OS=Homo sapiens OX=9606 GN=TRIP11 PE=1 SV=3 4.56 2054.6 - 1.40E+06 - - - -1.9449 - 2.666 0.392 - 287.6 1 2 1 -0.0027 12 0 0 0 2.93E+08 2.20E+08 - - - 5.6277 0.9995 221125_WJC_METTL3_EV_vs_WT_F05.09539.09539.3 3.90E-06 16/44 K.LSSAENDR[166.11]DILR[166.11].R "sp|Q15643|TRIPB_HUMAN,tr|H0YJ97|H0YJ97_HUMAN" 2 1407.7221 1.33 62088 9539 3 1407.721391 470.248 Thyroid receptor-interacting protein 11 OS=Homo sapiens OX=9606 GN=TRIP11 PE=1 SV=3 4.56 2054.9 - 2.67E+06 - - - -0.5008 - 3.044 0.321 - 465.4 1 2 1 -0.0007 12 0 0 0 2.93E+08 2.20E+08 - - - 5.2042 0.9386 221125_WJC_METTL3_EV_vs_WT_F05.09540.09540.2 0.0171 18-Aug V.EIIANDQGNR[166.11].L "sp|P11021|BIP_HUMAN,sp|P48741|HSP77_HUMAN,sp|P54652|HSP72_HUMAN,sp|P0DMV8|HS71A_HUMAN,sp|P34931|HS71L_HUMAN,sp|P11142|HSP7C_HUMAN,sp|P0DMV9|HS71B_HUMAN,sp|P17066|HSP76_HUMAN,tr|E9PQQ4|E9PQQ4_HUMAN,tr|E9PNE6|E9PNE6_HUMAN,tr|E9PKE3|E9PKE3_HUMAN,tr|A0A7P0TB36|A0A7P0TB36_HUMAN,tr|E9PLF4|E9PLF4_HUMAN,tr|A0A7P0TAI0|A0A7P0TAI0_HUMAN,tr|Q53FA3|Q53FA3_HUMAN,tr|E9PI65|E9PI65_HUMAN,tr|E9PK54|E9PK54_HUMAN,tr|E9PN25|E9PN25_HUMAN,tr|E9PPY6|E9PPY6_HUMAN,tr|E9PQK7|E9PQK7_HUMAN,tr|A0A0G2JIW1|A0A0G2JIW1_HUMAN" 21 1138.5606 10.99 62089 9540 2 1138.563015 570.2876 Endoplasmic reticulum chaperone BiP OS=Homo sapiens OX=9606 GN=HSPA5 PE=1 SV=2 4.37 2055 - 1.20E+06 - - - 2.1035 - 1.929 0.309 - 195.4 1 1 0 0.0024 10 0 0 0 2.36E+08 2.14E+07 - - - 3.1564 0.9997 221125_WJC_METTL3_EV_vs_WT_F05.09541.09541.2 1.44E-05 16-Sep R.HTLSDMEYR.L sp|Q8WVV4|POF1B_HUMAN 1 1150.5077 51.72 62090 9541 2 1150.508238 576.2611 Protein POF1B OS=Homo sapiens OX=9606 GN=POF1B PE=1 SV=3 5.32 2055.1 - 1.14E+06 - - - 0.4607 - 1.795 0.373 - 234.3 1 2 0 0.0005 9 0 0 0 1.01E+07 1.96E+05 - - - 3.4883 0.9397 221125_WJC_METTL3_EV_vs_WT_F05.09542.09542.2 0.00286 16-Dec Y.PDGIISK[136.11]PK[136.11].N sp|Q86U44|MTA70_HUMAN 1 969.583 0.001 62091 9542 2 969.579666 485.7988 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 9.01 2055.2 - 1.01E+06 - - - -3.42 - 2.137 0.41 - 313.8 1 1 0 -0.0033 9 0 0 0 0.00E+00 1.08E+07 - - - 4.2652 0.948 221125_WJC_METTL3_EV_vs_WT_F05.09547.09547.2 0.807 14-Sep R.QLDFNSSK[136.11].D "sp|P53621|COPA_HUMAN,tr|A0A3B3ISC6|A0A3B3ISC6_HUMAN,tr|A0A3B3ITV3|A0A3B3ITV3_HUMAN,tr|A0A3B3IS84|A0A3B3IS84_HUMAN,tr|A0A3B3IU89|A0A3B3IU89_HUMAN,tr|A0A3B3ISK1|A0A3B3ISK1_HUMAN,tr|A0A3B3IT15|A0A3B3IT15_HUMAN" 7 945.4647 0.17 62094 9547 2 945.46335 473.7396 Coatomer subunit alpha OS=Homo sapiens OX=9606 GN=COPA PE=1 SV=2 5.84 2055.8 - 855734 - - - -1.4395 - 1.272 0.003 - 215.7 1 2 0 -0.0014 8 0 0 0 2.00E+06 1.17E+07 - - - -0.2117 0.9997 221125_WJC_METTL3_EV_vs_WT_F05.09553.09553.2 7.30E-05 18-Oct K.STQTILGQQR[166.11].A "sp|Q14687|GSE1_HUMAN,tr|H0Y613|H0Y613_HUMAN" 2 1140.6127 0.78 62098 9553 2 1140.610773 571.3136 Genetic suppressor element 1 OS=Homo sapiens OX=9606 GN=GSE1 PE=1 SV=3 9.47 2056.5 - 927135 - - - -1.6509 - 1.941 0.433 - 450.3 1 2 0 -0.0019 10 0 0 0 2.61E+07 3.36E+07 - - - 4.0897 0.9994 221125_WJC_METTL3_EV_vs_WT_F05.09558.09558.2 0.000319 22-Dec R.AGGPTTPLSPTR.L "sp|P20700|LMNB1_HUMAN,tr|A0A0D9SFY5|A0A0D9SFY5_HUMAN,tr|E9PBF6|E9PBF6_HUMAN,tr|A0A0D9SFE5|A0A0D9SFE5_HUMAN" 4 1153.6091 70.54 62101 9558 2 1153.606022 577.8118 Lamin-B1 OS=Homo sapiens OX=9606 GN=LMNB1 PE=1 SV=2 9.79 2057.1 - 1.38E+06 - - - -2.7002 - 2.202 0.428 - 346.5 1 2 0 -0.0031 12 0 0 0 2.47E+08 3.50E+06 - - - 4.2782 0.9994 221125_WJC_METTL3_EV_vs_WT_F05.09561.09561.2 0.0231 18-Dec R.TVDLSSHLAK.V "sp|P04843|RPN1_HUMAN,tr|F8WF32|F8WF32_HUMAN" 2 1069.5768 1.35 62102 9561 2 1069.575185 535.7957 Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit 1 OS=Homo sapiens OX=9606 GN=RPN1 PE=1 SV=1 6.41 2057.5 - 1.65E+06 - - - -1.4856 - 1.917 0.32 - 313.9 1 2 0 -0.0016 10 0 0 0 5.12E+07 3.80E+07 - - - 3.2205 0.9922 221125_WJC_METTL3_EV_vs_WT_F05.09562.09562.3 0.227 Aug-36 K.LHESYGNPLR.V "sp|O95619|YETS4_HUMAN,tr|F8W1B9|F8W1B9_HUMAN,tr|F8VTR4|F8VTR4_HUMAN" 3 1184.5938 2.96 62103 9562 3 1184.591794 395.8719 YEATS domain-containing protein 4 OS=Homo sapiens OX=9606 GN=YEATS4 PE=1 SV=1 6.75 2057.6 - 1.61E+06 - - - -1.7111 - 1.48 0.226 - 77 1 2 0 -0.002 10 0 0 0 5.61E+07 1.89E+07 - - - 2.204 0.9978 221125_WJC_METTL3_EV_vs_WT_F05.09569.09569.2 2.22E-06 20-Dec R.DGLGSDNIGSR[166.11].M sp|P98175|RBM10_HUMAN 1 1099.5133 2.86 62107 9569 2 1099.507813 550.7639 RNA-binding protein 10 OS=Homo sapiens OX=9606 GN=RBM10 PE=1 SV=3 4.21 2058.4 - 1.53E+06 - - - -5.0222 - 2.462 0.471 - 373.3 1 2 0 -0.0055 11 0 0 0 4.25E+08 1.49E+08 - - - 4.9554 0.9992 221125_WJC_METTL3_EV_vs_WT_F05.09570.09570.2 6.46E-05 18-Dec R.YPDGIISKPK[136.11].N sp|Q86U44|MTA70_HUMAN 1 1124.6321 - 62108 9570 2 1124.628051 563.3233 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 8.5 2058.6 - 876246 - - - -3.6092 - 2.073 0.534 - 462.7 1 2 0 -0.0041 10 0 0 0 - - - - - 5.0187 0.8125 221125_WJC_METTL3_EV_vs_WT_F05.09574.09574.2 0.0585 14-Jul V.DLSSHLAK[136.11].V "sp|P04843|RPN1_HUMAN,tr|F8WF32|F8WF32_HUMAN" 2 877.4749 1.36 62110 9574 2 877.475966 439.7447 Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit 1 OS=Homo sapiens OX=9606 GN=RPN1 PE=1 SV=1 6.74 2059 - 815588 - - - 1.2365 - 1.357 0.221 - 130.3 1 1 0 0.0011 8 0 0 0 2.14E+07 1.57E+07 - - - 1.5937 0.9995 221125_WJC_METTL3_EV_vs_WT_F05.09575.09575.2 8.58E-05 16-Sep K.NDPSLPEPK[136.11].C "sp|O43776|SYNC_HUMAN,tr|K7EIU7|K7EIU7_HUMAN,tr|K7EJ19|K7EJ19_HUMAN,tr|K7EMQ6|K7EMQ6_HUMAN,tr|K7EPK2|K7EPK2_HUMAN" 5 1003.5066 0.27 62111 9575 2 1003.504278 502.7606 "Asparagine--tRNA ligase, cytoplasmic OS=Homo sapiens OX=9606 GN=NARS1 PE=1 SV=1" 4.37 2059.1 - 876627 - - - -2.289 - 1.616 0.512 - 317.6 1 2 0 -0.0023 9 0 0 0 9.55E+06 3.58E+07 - - - 4.2104 0.9997 221125_WJC_METTL3_EV_vs_WT_F05.09580.09580.2 0.000347 24-Nov R.AASSAAQGAFQGN.- sp|O15127|SCAM2_HUMAN 1 1178.5316 - 62114 9580 2 1178.533155 590.2731 Secretory carrier-associated membrane protein 2 OS=Homo sapiens OX=9606 GN=SCAMP2 PE=1 SV=2 5.57 2059.8 - 1.24E+06 - - - 1.3067 - 1.804 0.503 - 237 1 2 0 0.0015 13 0 0 0 - - - - - 4.2699 0.997 221125_WJC_METTL3_EV_vs_WT_F05.09584.09584.2 0.156 16-Oct R.NVFHIASQK[136.11].N "sp|Q8N0T1|RBIS_HUMAN,tr|A0A087WWE7|A0A087WWE7_HUMAN,tr|E5RGR5|E5RGR5_HUMAN" 3 1050.5702 2.09 62118 9584 2 1050.569105 526.2924 Ribosomal biogenesis factor OS=Homo sapiens OX=9606 GN=RBIS PE=1 SV=4 8.76 2060.2 - 619826 - - - -1.0223 - 1.417 0.212 - 214.5 1 2 0 -0.0011 9 0 0 0 1.10E+08 5.26E+07 - - - 1.6148 0.9807 221125_WJC_METTL3_EV_vs_WT_F05.09586.09586.2 0.000171 16-Oct Y.PDGIISKPK[136.11].N sp|Q86U44|MTA70_HUMAN 1 961.5688 - 62120 9586 2 961.568087 481.7917 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 9.01 2060.5 - 472177 - - - -0.7228 - 1.728 0.398 - 276 1 1 0 -0.0007 9 0 0 0 - - - - - 3.5628 0.9998 221125_WJC_METTL3_EV_vs_WT_F05.09587.09587.2 0.0488 14-Nov R.K[136.11]ENPLQFK[136.11].F "sp|P15311|EZRI_HUMAN,sp|P35241|RADI_HUMAN,tr|A0A2R8Y5P0|A0A2R8Y5P0_HUMAN,tr|A0A2R8Y5S7|A0A2R8Y5S7_HUMAN,tr|E7EQR4|E7EQR4_HUMAN,tr|E9PQ82|E9PQ82_HUMAN,tr|A0A2R8Y7M3|A0A2R8Y7M3_HUMAN,tr|E9PNV3|E9PNV3_HUMAN" 8 1018.5782 1.2 62121 9587 2 1018.577129 510.2964 Ezrin OS=Homo sapiens OX=9606 GN=EZR PE=1 SV=4 8.59 2060.6 - 392679 - - - -1.0819 - 2.245 0.374 - 419.2 1 2 0 -0.0011 8 0 0 0 1.21E+07 1.01E+07 - - - 4.242 0.9996 221125_WJC_METTL3_EV_vs_WT_F05.09589.09589.3 0.022 Oct-40 R.VEIIANDQGNR.L "sp|P11021|BIP_HUMAN,sp|P48741|HSP77_HUMAN,sp|P54652|HSP72_HUMAN,sp|P0DMV8|HS71A_HUMAN,sp|P34931|HS71L_HUMAN,sp|P11142|HSP7C_HUMAN,sp|P0DMV9|HS71B_HUMAN,sp|P17066|HSP76_HUMAN,tr|E9PQQ4|E9PQQ4_HUMAN,tr|E9PNE6|E9PNE6_HUMAN,tr|E9PKE3|E9PKE3_HUMAN,tr|A0A7P0TB36|A0A7P0TB36_HUMAN,tr|E9PLF4|E9PLF4_HUMAN,tr|A0A7P0TAI0|A0A7P0TAI0_HUMAN,tr|Q53FA3|Q53FA3_HUMAN,tr|E9PI65|E9PI65_HUMAN,tr|E9PK54|E9PK54_HUMAN,tr|E9PN25|E9PN25_HUMAN,tr|E9PPY6|E9PPY6_HUMAN,tr|E9PQK7|E9PQK7_HUMAN,tr|A0A0G2JIW1|A0A0G2JIW1_HUMAN" 21 1227.6208 0.14 62122 9589 3 1227.617961 410.2142 Endoplasmic reticulum chaperone BiP OS=Homo sapiens OX=9606 GN=HSPA5 PE=1 SV=2 4.37 2060.9 - 840965 - - - -2.2833 - 2.149 0.346 - 162.8 1 2 0 -0.0028 11 0 0 0 1.49E+08 1.05E+09 - - - 4.57 0.9582 221125_WJC_METTL3_EV_vs_WT_F05.09592.09592.2 0.838 14-Aug P.DGIISK[136.11]PK[136.11].N sp|Q86U44|MTA70_HUMAN 1 872.5302 0 62124 9592 2 872.528367 437.2724 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 8.59 2061.2 - 2.78E+06 - - - -2.1214 - 1.696 0.394 - 196.2 1 1 0 -0.0019 8 0 0 0 2.34E+06 2.39E+09 - - - 3.5437 0.9995 221125_WJC_METTL3_EV_vs_WT_F05.09598.09598.2 0.00586 16-Oct R.NVFHIASQK.N "sp|Q8N0T1|RBIS_HUMAN,tr|A0A087WWE7|A0A087WWE7_HUMAN,tr|E5RGR5|E5RGR5_HUMAN" 3 1042.556 2.09 62128 9598 2 1042.553968 522.2853 Ribosomal biogenesis factor OS=Homo sapiens OX=9606 GN=RBIS PE=1 SV=4 8.76 2061.9 - 2.40E+06 - - - -1.9289 - 1.818 0.422 - 317.7 1 2 0 -0.002 9 0 0 0 1.10E+08 5.26E+07 - - - 3.8865 0.9841 221125_WJC_METTL3_EV_vs_WT_F05.09607.09607.2 0.143 20-Jun R.GAAPPPPPVPR[166.11].G sp|Q07666|KHDR1_HUMAN 1 1064.6006 4.23 62134 9607 2 1064.600127 533.3076 "KH domain-containing, RNA-binding, signal transduction-associated protein 1 OS=Homo sapiens OX=9606 GN=KHDRBS1 PE=1 SV=1" 9.75 2063 - 372603 - - - -0.4762 - 1.164 0.136 - 109.4 2 2 0 -0.0005 11 0 0 0 2.13E+07 5.03E+06 - - - 0.3217 0.8945 221125_WJC_METTL3_EV_vs_WT_F05.09613.09613.2 0.00044 16-Sep R.YPDGIISK[136.11]P.K sp|Q86U44|MTA70_HUMAN 1 996.5371 0.74 62137 9613 2 996.533505 499.2758 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 5.83 2063.7 - 1.13E+06 - - - -3.6547 - 1.764 0.408 - 226.5 1 1 0 -0.0036 9 0 0 0 1.93E+08 2.59E+08 - - - 3.6954 0.9994 221125_WJC_METTL3_EV_vs_WT_F05.09621.09621.2 0.00315 16-Sep R.DTQEVPLEK.A "sp|Q9Y5A9|YTHD2_HUMAN,sp|Q9BYJ9|YTHD1_HUMAN,sp|Q7Z739|YTHD3_HUMAN,tr|A0A087X0Q1|A0A087X0Q1_HUMAN,tr|A0A024R7W5|A0A024R7W5_HUMAN,tr|A0A087WY31|A0A087WY31_HUMAN" 6 1057.5292 1.52 62142 9621 2 1057.52854 529.7719 YTH domain-containing family protein 2 OS=Homo sapiens OX=9606 GN=YTHDF2 PE=1 SV=2 4.14 2064.7 - 645616 - - - -0.5815 - 1.561 0.354 - 321.3 1 2 0 -0.0006 9 0 0 0 1.15E+09 7.59E+08 - - - 2.9438 0.9987 221125_WJC_METTL3_EV_vs_WT_F05.09626.09626.2 0.021 16-Aug R.DTQEVPLEK[136.11].A "sp|Q9Y5A9|YTHD2_HUMAN,sp|Q9BYJ9|YTHD1_HUMAN,sp|Q7Z739|YTHD3_HUMAN,tr|A0A087X0Q1|A0A087X0Q1_HUMAN,tr|A0A024R7W5|A0A024R7W5_HUMAN,tr|A0A087WY31|A0A087WY31_HUMAN" 6 1065.5434 1.52 62144 9626 2 1065.541804 533.779 YTH domain-containing family protein 2 OS=Homo sapiens OX=9606 GN=YTHDF2 PE=1 SV=2 4.14 2065.3 - 927450 - - - -1.4556 - 1.675 0.264 - 279.4 1 2 0 -0.0016 9 0 0 0 1.15E+09 7.59E+08 - - - 2.4827 0.9997 221125_WJC_METTL3_EV_vs_WT_F05.09629.09629.2 0.00145 18-Dec R.YPDGIISKPK.N sp|Q86U44|MTA70_HUMAN 1 1116.6179 0 62145 9629 2 1116.615641 559.3162 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 8.5 2065.6 - 1.44E+06 - - - -2.032 - 1.92 0.522 - 378 1 2 0 -0.0023 10 0 0 0 2.54E+08 1.79E+11 - - - 4.7166 0.999 221125_WJC_METTL3_EV_vs_WT_F05.09633.09633.3 0.00232 13/44 K.LVEK[136.11]GETDLIQK[136.11].A "sp|P42704|LPPRC_HUMAN,tr|A0A804HI14|A0A804HI14_HUMAN,tr|A0A804HL40|A0A804HL40_HUMAN,tr|A0A804HKJ0|A0A804HKJ0_HUMAN,tr|A0A804HKR3|A0A804HKR3_HUMAN,tr|A0A804HIN4|A0A804HIN4_HUMAN,tr|A0A804HLG8|A0A804HLG8_HUMAN,tr|A0A804HHY9|A0A804HHY9_HUMAN,tr|A0A804HJH8|A0A804HJH8_HUMAN,tr|A0A804HI40|A0A804HI40_HUMAN,tr|A0A804HJZ1|A0A804HJZ1_HUMAN,tr|A0A804HIQ7|A0A804HIQ7_HUMAN,tr|A0A804HK30|A0A804HK30_HUMAN,tr|A0A804HKI2|A0A804HKI2_HUMAN,tr|A0A804HJI0|A0A804HJI0_HUMAN,tr|A0A804HIG4|A0A804HIG4_HUMAN,tr|A0A804HLK8|A0A804HLK8_HUMAN" 17 1387.7893 0.56 62147 9633 3 1387.789269 463.6037 "Leucine-rich PPR motif-containing protein, mitochondrial OS=Homo sapiens OX=9606 GN=LRPPRC PE=1 SV=3" 4.68 2066.2 - 1.60E+06 - - - -0.0555 - 2.373 0.318 - 155.9 1 2 1 -0.0001 12 0 0 0 2.97E+07 5.32E+07 - - - 4.4807 0.9994 221125_WJC_METTL3_EV_vs_WT_F05.09639.09639.2 0.000147 13/22 R.SPPPGMGLNQNR[166.11].G sp|P23246|SFPQ_HUMAN 1 1276.6222 0.2 62150 9639 2 1276.620906 639.3184 "Splicing factor, proline- and glutamine-rich OS=Homo sapiens OX=9606 GN=SFPQ PE=1 SV=2" 9.47 2066.8 - 2.47E+06 - - - -0.9932 - 2.167 0.265 - 457.6 1 2 0 -0.0013 12 0 0 0 3.93E+07 1.98E+08 - - - 3.0327 0.9993 221125_WJC_METTL3_EV_vs_WT_F05.09643.09643.2 0.000163 20-Nov R.VEIIANDQGNR[166.11].L "sp|P11021|BIP_HUMAN,sp|P48741|HSP77_HUMAN,sp|P54652|HSP72_HUMAN,sp|P0DMV8|HS71A_HUMAN,sp|P34931|HS71L_HUMAN,sp|P11142|HSP7C_HUMAN,sp|P0DMV9|HS71B_HUMAN,sp|P17066|HSP76_HUMAN,tr|E9PQQ4|E9PQQ4_HUMAN,tr|E9PNE6|E9PNE6_HUMAN,tr|E9PKE3|E9PKE3_HUMAN,tr|A0A7P0TB36|A0A7P0TB36_HUMAN,tr|E9PLF4|E9PLF4_HUMAN,tr|A0A7P0TAI0|A0A7P0TAI0_HUMAN,tr|Q53FA3|Q53FA3_HUMAN,tr|E9PI65|E9PI65_HUMAN,tr|E9PK54|E9PK54_HUMAN,tr|E9PN25|E9PN25_HUMAN,tr|E9PPY6|E9PPY6_HUMAN,tr|E9PQK7|E9PQK7_HUMAN,tr|A0A0G2JIW1|A0A0G2JIW1_HUMAN" 21 1237.629 0.17 62152 9643 2 1237.625134 619.8218 Endoplasmic reticulum chaperone BiP OS=Homo sapiens OX=9606 GN=HSPA5 PE=1 SV=2 4.37 2067.2 - 4.78E+06 - - - -3.1512 - 2.223 0.449 - 350.7 1 2 0 -0.0039 11 0 0 0 5.96E+09 3.45E+10 - - - 4.5172 0.9952 221125_WJC_METTL3_EV_vs_WT_F05.09645.09645.2 4.05 14-Aug K.IQDWYDKK.G sp|P35527|K1C9_HUMAN 1 1094.5397 999 62154 9645 2 1094.538135 548.2771 "Keratin, type I cytoskeletal 9 OS=Homo sapiens OX=9606 GN=KRT9 PE=1 SV=3" 5.96 2067.4 - 6.46E+06 - - - -1.3933 - 1.31 0.211 - 204.5 1 2 0 -0.0015 8 0 0 0 3.17E+09 0.00E+00 - - - 1.4134 0.9992 221125_WJC_METTL3_EV_vs_WT_F05.09646.09646.2 0.00929 18-Dec R.TNQELQEINR.V "sp|P07355|ANXA2_HUMAN,sp|A6NMY6|AXA2L_HUMAN,tr|H0YL33|H0YL33_HUMAN,tr|H0YMU9|H0YMU9_HUMAN,tr|H0YNA0|H0YNA0_HUMAN,tr|H0YMM1|H0YMM1_HUMAN,tr|H0YM50|H0YM50_HUMAN,tr|H0YMD0|H0YMD0_HUMAN,tr|H0YMW4|H0YMW4_HUMAN,tr|H0YLE2|H0YLE2_HUMAN,tr|H0YN42|H0YN42_HUMAN,tr|H0YN28|H0YN28_HUMAN,tr|A0A7I2V4P4|A0A7I2V4P4_HUMAN,tr|H0YNP5|H0YNP5_HUMAN,tr|H0YNB8|H0YNB8_HUMAN,tr|H0YKS4|H0YKS4_HUMAN" 16 1243.6157 999 62155 9646 2 1243.613061 622.8151 Annexin A2 OS=Homo sapiens OX=9606 GN=ANXA2 PE=1 SV=2 4.53 2067.5 - 1.48E+06 - - - -2.1052 - 1.942 0.337 - 465.3 1 2 0 -0.0026 10 0 0 0 5.32E+07 0.00E+00 - - - 3.3819 0.9911 221125_WJC_METTL3_EV_vs_WT_F05.09659.09659.3 0.00642 Oct-36 K.KDVDNAYMIK.V sp|P35908|K22E_HUMAN 1 1195.5907 999 62158 9659 3 1195.585354 399.5375 "Keratin, type II cytoskeletal 2 epidermal OS=Homo sapiens OX=9606 GN=KRT2 PE=1 SV=2" 5.96 2069.5 - 3.60E+06 - - - -4.479 - 1.613 0.316 - 88.4 1 2 0 -0.0054 10 0 0 0 2.33E+08 0.00E+00 - - - 3.4579 0.9977 221125_WJC_METTL3_EV_vs_WT_F05.09666.09666.2 0.0283 16-Oct K.YKDDPVDLR.L "sp|Q9Y2W1|TR150_HUMAN,tr|A0A3B3ITZ9|A0A3B3ITZ9_HUMAN" 2 1119.556 2.63 62161 9666 2 1119.555478 560.7853 Thyroid hormone receptor-associated protein 3 OS=Homo sapiens OX=9606 GN=THRAP3 PE=1 SV=2 4.43 2070.3 - 7.68E+06 - - - -0.5002 - 1.987 0.417 - 315.7 1 2 1 -0.0006 9 0 0 0 1.13E+10 4.31E+09 - - - 4.1072 1 221125_WJC_METTL3_EV_vs_WT_F05.09671.09671.2 1.86E-06 26-Dec A.GGPGPGGFGAQGPK[136.11].G "sp|P0DMV8|HS71A_HUMAN,sp|P0DMV9|HS71B_HUMAN,tr|V9GZ37|V9GZ37_HUMAN,tr|A0A0G2JIW1|A0A0G2JIW1_HUMAN" 4 1190.5924 0.12 62162 9671 2 1190.589496 596.3035 Heat shock 70 kDa protein 1A OS=Homo sapiens OX=9606 GN=HSPA1A PE=1 SV=1 8.75 2071 - 5.22E+06 - - - -2.4148 - 2.37 0.619 - 504.6 1 1 0 -0.0029 14 0 0 0 1.25E+08 1.06E+09 - - - 5.7774 0.9915 221125_WJC_METTL3_EV_vs_WT_F05.09675.09675.3 0.00345 14/36 F.AAQELIEVK[136.11]R[166.11].G "sp|Q86U44|MTA70_HUMAN,tr|F5H6D8|F5H6D8_HUMAN,tr|H0YFV6|H0YFV6_HUMAN,tr|B4DTN4|B4DTN4_HUMAN" 4 1173.6836 0.32 62164 9675 3 1173.683699 392.2352 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 6.19 2071.5 - 5.77E+06 - - - 0.0486 - 2.69 0.355 - 272.2 1 1 0 0.0001 10 0 0 0 3.11E+07 9.69E+07 - - - 5.3878 0.9995 221125_WJC_METTL3_EV_vs_WT_F05.09677.09677.2 3.86E-08 15/24 K.AVANYDSVEEGEK[136.11].V "sp|P51659|DHB4_HUMAN,tr|A0A804HK88|A0A804HK88_HUMAN,tr|A0A2R8YD50|A0A2R8YD50_HUMAN,tr|A0A804HKB5|A0A804HKB5_HUMAN,tr|E7ER27|E7ER27_HUMAN,tr|A0A2R8YF45|A0A2R8YF45_HUMAN,tr|E7EPL9|E7EPL9_HUMAN,tr|A0A804HKU2|A0A804HKU2_HUMAN,tr|A0A2R8YDT8|A0A2R8YDT8_HUMAN,tr|A0A804HK65|A0A804HK65_HUMAN" 10 1417.6453 0.61 62165 9677 2 1417.640626 709.8299 Peroxisomal multifunctional enzyme type 2 OS=Homo sapiens OX=9606 GN=HSD17B4 PE=1 SV=3 4 2071.8 - 2.09E+06 - - - -3.2646 - 2.828 0.527 - 703.3 1 2 0 -0.0046 13 0 0 0 4.60E+07 7.48E+07 - - - 5.6001 1 221125_WJC_METTL3_EV_vs_WT_F05.09690.09690.2 2.33E-07 13/24 K.AVANYDSVEEGEK.V "sp|P51659|DHB4_HUMAN,tr|A0A804HK88|A0A804HK88_HUMAN,tr|A0A2R8YD50|A0A2R8YD50_HUMAN,tr|A0A804HKB5|A0A804HKB5_HUMAN,tr|E7ER27|E7ER27_HUMAN,tr|A0A2R8YF45|A0A2R8YF45_HUMAN,tr|E7EPL9|E7EPL9_HUMAN,tr|A0A804HKU2|A0A804HKU2_HUMAN,tr|A0A2R8YDT8|A0A2R8YDT8_HUMAN,tr|A0A804HK65|A0A804HK65_HUMAN" 10 1409.6311 0.61 62170 9690 2 1409.627995 705.8228 Peroxisomal multifunctional enzyme type 2 OS=Homo sapiens OX=9606 GN=HSD17B4 PE=1 SV=3 4 2073.5 - 1.84E+06 - - - -2.1701 - 2.619 0.57 - 481.6 1 2 0 -0.0031 13 0 0 0 4.60E+07 7.48E+07 - - - 5.7211 0.9958 221125_WJC_METTL3_EV_vs_WT_F05.09692.09692.2 0.2 18-Oct R.ESAINVAEGK.K "sp|Q9UJZ1|STML2_HUMAN,tr|A0A087WYB4|A0A087WYB4_HUMAN,tr|F2Z2I8|F2Z2I8_HUMAN" 3 1016.5138 3.47 62171 9692 2 1016.509624 509.2642 "Stomatin-like protein 2, mitochondrial OS=Homo sapiens OX=9606 GN=STOML2 PE=1 SV=1" 4.53 2073.7 - 1.38E+06 - - - -4.1465 - 1.941 0.318 - 301.5 1 2 0 -0.0042 10 0 0 0 1.40E+07 4.04E+06 - - - 3.2396 0.9996 221125_WJC_METTL3_EV_vs_WT_F05.09704.09704.2 5.55E-05 18-Oct R.GNVLVLSQHK[136.11].F "sp|Q14671|PUM1_HUMAN,tr|Q5T1Z8|Q5T1Z8_HUMAN,tr|H0YDK8|H0YDK8_HUMAN,tr|H0YC97|H0YC97_HUMAN,tr|H0YEH2|H0YEH2_HUMAN,tr|Q5T1Z4|Q5T1Z4_HUMAN,tr|H0YDC5|H0YDC5_HUMAN,tr|E9PR38|E9PR38_HUMAN" 8 1101.6386 1.85 62175 9704 2 1101.636084 551.8266 Pumilio homolog 1 OS=Homo sapiens OX=9606 GN=PUM1 PE=1 SV=3 8.76 2075.3 - 3.60E+06 - - - -2.2775 - 1.804 0.505 - 406.1 1 2 0 -0.0025 10 0 0 0 2.39E+08 1.29E+08 - - - 4.417 0.9811 221125_WJC_METTL3_EV_vs_WT_F05.09706.09706.2 0.16 14-Oct Y.KDDPVDLR.L "sp|Q9Y2W1|TR150_HUMAN,tr|A0A3B3ITZ9|A0A3B3ITZ9_HUMAN" 2 956.4927 3.25 62176 9706 2 956.492878 479.2536 Thyroid hormone receptor-associated protein 3 OS=Homo sapiens OX=9606 GN=THRAP3 PE=1 SV=2 4.43 2075.5 - 5.74E+06 - - - 0.1756 - 2.034 0.316 - 435.1 1 1 0 0.0002 8 0 0 0 2.28E+08 7.01E+07 - - - 3.5163 0.9967 221125_WJC_METTL3_EV_vs_WT_F05.09709.09709.3 5.69E-05 Oct-32 R.MDYEDDRLR.D "sp|P43243|MATR3_HUMAN,tr|A8MXP9|A8MXP9_HUMAN,tr|D6R991|D6R991_HUMAN,tr|A0A0R4J2E8|A0A0R4J2E8_HUMAN,tr|D6REM6|D6REM6_HUMAN" 5 1211.5241 1.21 62177 9709 3 1211.519935 404.8486 Matrin-3 OS=Homo sapiens OX=9606 GN=MATR3 PE=1 SV=2 4.23 2075.8 - 1.26E+07 - - - -3.4263 - 1.602 0.441 - 178.1 1 2 1 -0.0042 9 0 0 0 2.81E+09 2.31E+09 - - - 4.8758 0.9954 221125_WJC_METTL3_EV_vs_WT_F05.09710.09710.2 0.00245 16-Dec R.MDYEDDRLR.D "sp|P43243|MATR3_HUMAN,tr|A8MXP9|A8MXP9_HUMAN,tr|D6R991|D6R991_HUMAN,tr|A0A0R4J2E8|A0A0R4J2E8_HUMAN,tr|D6REM6|D6REM6_HUMAN" 5 1211.5241 1.24 62178 9710 2 1211.522552 606.7693 Matrin-3 OS=Homo sapiens OX=9606 GN=MATR3 PE=1 SV=2 4.23 2076 - 3.46E+06 - - - -1.2662 - 1.372 0.488 - 357.4 1 2 1 -0.0015 9 0 0 0 6.96E+08 5.63E+08 - - - 3.5599 0.9886 221125_WJC_METTL3_EV_vs_WT_F05.09711.09711.2 0.00745 16-Dec R.MDYEDDR[166.11]LR[166.11].D "sp|P43243|MATR3_HUMAN,tr|A8MXP9|A8MXP9_HUMAN,tr|D6R991|D6R991_HUMAN,tr|A0A0R4J2E8|A0A0R4J2E8_HUMAN,tr|D6REM6|D6REM6_HUMAN" 5 1231.5406 1.24 62179 9711 2 1231.537947 616.7776 Matrin-3 OS=Homo sapiens OX=9606 GN=MATR3 PE=1 SV=2 4.23 2076 - 4.30E+06 - - - -2.1753 - 1.321 0.454 - 348.5 1 2 1 -0.0027 9 0 0 0 6.96E+08 5.63E+08 - - - 3.1988 0.9999 221125_WJC_METTL3_EV_vs_WT_F05.09720.09720.3 2.29E-06 19/52 K.IVIGYQSHADTATK[136.11].S "sp|P06730|IF4E_HUMAN,tr|D6RBW1|D6RBW1_HUMAN" 2 1510.7871 1.46 62182 9720 3 1510.78076 504.603 Eukaryotic translation initiation factor 4E OS=Homo sapiens OX=9606 GN=EIF4E PE=1 SV=2 6.74 2077.3 - 4.27E+06 - - - -4.2018 - 2.911 0.594 - 395.1 1 2 0 -0.0063 14 0 0 0 3.74E+08 2.55E+08 - - - 8.0003 0.9987 221125_WJC_METTL3_EV_vs_WT_F05.09721.09721.3 0.000248 Sep-32 R.MDYEDDR[166.11]LR[166.11].D "sp|P43243|MATR3_HUMAN,tr|A8MXP9|A8MXP9_HUMAN,tr|D6R991|D6R991_HUMAN,tr|A0A0R4J2E8|A0A0R4J2E8_HUMAN,tr|D6REM6|D6REM6_HUMAN" 5 1231.5406 1.21 62183 9721 3 1231.537314 411.5208 Matrin-3 OS=Homo sapiens OX=9606 GN=MATR3 PE=1 SV=2 4.23 2077.3 - 4.05E+07 - - - -2.6893 - 1.715 0.456 - 204.1 1 2 1 -0.0033 9 0 0 0 2.80E+09 2.31E+09 - - - 5.2487 0.9996 221125_WJC_METTL3_EV_vs_WT_F05.09730.09730.2 1.07 20-Oct R.AGELTEDEVER[166.11].V sp|P62269|RS18_HUMAN 1 1256.576 1.43 62188 9730 2 1256.575673 629.2953 40S ribosomal protein S18 OS=Homo sapiens OX=9606 GN=RPS18 PE=1 SV=3 3.91 2078.4 - 1.61E+06 - - - -0.2563 - 1.931 0.327 - 414.6 1 2 0 -0.0003 11 0 0 0 7.49E+07 5.25E+07 - - - 3.2363 0.9634 221125_WJC_METTL3_EV_vs_WT_F05.09735.09735.3 0.00128 13/48 R.LHPELSGPGVAAK[136.11].V sp|Q6DD87|ZN787_HUMAN 1 1282.7125 0.82 62191 9735 3 1282.700617 428.5781 Zinc finger protein 787 OS=Homo sapiens OX=9606 GN=ZNF787 PE=1 SV=4 6.75 2079 - 1.87E+06 - - - -9.253 - 2.327 0.31 - 209.6 1 2 0 -0.0119 13 0 0 0 1.23E+07 1.50E+07 - - - 4.2828 0.999 221125_WJC_METTL3_EV_vs_WT_F05.09736.09736.2 1.67E-05 20-Nov R.AGELTEDEVER.V sp|P62269|RS18_HUMAN 1 1246.5677 1.43 62192 9736 2 1246.562642 624.2911 40S ribosomal protein S18 OS=Homo sapiens OX=9606 GN=RPS18 PE=1 SV=3 3.91 2079.2 - 1.27E+06 - - - -4.0776 - 2.568 0.496 - 625.7 1 2 0 -0.0051 11 0 0 0 7.49E+07 5.25E+07 - - - 5.2542 0.9989 221125_WJC_METTL3_EV_vs_WT_F05.09741.09741.3 0.0352 Dec-44 R.IYDLNK[136.11]PEAEPK[136.11].E sp|Q9Y3F4|STRAP_HUMAN 1 1431.758 0.71 62195 9741 3 1431.754141 478.26 Serine-threonine kinase receptor-associated protein OS=Homo sapiens OX=9606 GN=STRAP PE=1 SV=1 4.68 2079.7 - 7.48E+06 - - - -2.7274 - 1.644 0.373 - 177.8 1 2 0 -0.0039 12 0 0 0 1.29E+08 1.82E+08 - - - 4.0755 0.8252 221125_WJC_METTL3_EV_vs_WT_F05.09742.09742.2 0.0359 20-Aug S.LQAEEEPMLER[166.11].R tr|C9JYJ8|C9JYJ8_HUMAN 1 1353.6474 0.13 62196 9742 2 1353.649044 677.831 Replication initiator 1 (Fragment) OS=Homo sapiens OX=9606 GN=REPIN1 PE=1 SV=8 4.09 2079.9 - 2.06E+06 - - - 1.2248 - 1.49 0.208 - 121 1 1 0 0.0017 11 0 0 0 1.59E+07 1.27E+08 - - - 1.6556 1 221125_WJC_METTL3_EV_vs_WT_F05.09743.09743.3 3.66E-05 15/52 K.IVIGYQSHADTATK.S "sp|P06730|IF4E_HUMAN,tr|D6RBW1|D6RBW1_HUMAN" 2 1502.7729 1.47 62197 9743 3 1502.770147 501.9316 Eukaryotic translation initiation factor 4E OS=Homo sapiens OX=9606 GN=EIF4E PE=1 SV=2 6.74 2079.9 - 1.23E+07 - - - -1.8373 - 2.262 0.562 - 114.2 1 2 0 -0.0028 14 0 0 0 3.73E+08 2.54E+08 - - - 6.9742 0.9999 221125_WJC_METTL3_EV_vs_WT_F05.09747.09747.3 0.0414 13/44 R.IYDLNKPEAEPK.E sp|Q9Y3F4|STRAP_HUMAN 1 1415.7296 0.71 62199 9747 3 1415.727117 472.9172 Serine-threonine kinase receptor-associated protein OS=Homo sapiens OX=9606 GN=STRAP PE=1 SV=1 4.68 2080.4 - 5.04E+06 - - - -1.7864 - 2.148 0.437 - 185.1 1 2 0 -0.0025 12 0 0 0 1.29E+08 1.82E+08 - - - 5.5306 1 221125_WJC_METTL3_EV_vs_WT_F05.09748.09748.2 3.99E-05 13/22 K.GEDEEENNLEVR.E "sp|P04843|RPN1_HUMAN,tr|F8WF32|F8WF32_HUMAN" 2 1431.6114 1.26 62200 9748 2 1431.607495 716.813 Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit 1 OS=Homo sapiens OX=9606 GN=RPN1 PE=1 SV=1 3.83 2080.5 - 2.34E+06 - - - -2.7144 - 2.93 0.551 - 1029.8 1 2 0 -0.0039 12 0 0 0 8.12E+07 6.43E+07 - - - 5.938 0.9563 221125_WJC_METTL3_EV_vs_WT_F05.09749.09749.3 0.00962 Sep-32 R.MDYEDDR[166.11]LR.D "sp|P43243|MATR3_HUMAN,tr|A8MXP9|A8MXP9_HUMAN,tr|D6R991|D6R991_HUMAN,tr|A0A0R4J2E8|A0A0R4J2E8_HUMAN,tr|D6REM6|D6REM6_HUMAN" 5 1221.5324 - 62201 9749 3 1221.526939 408.1847 Matrin-3 OS=Homo sapiens OX=9606 GN=MATR3 PE=1 SV=2 4.23 2080.7 - 2.22E+06 - - - -4.4346 - 1.605 0.305 - 181.7 1 2 1 -0.0054 9 0 0 0 - - - - - 3.3648 1 221125_WJC_METTL3_EV_vs_WT_F05.09750.09750.2 0.00122 13/22 K.GEDEEENNLEVR[166.11].E "sp|P04843|RPN1_HUMAN,tr|F8WF32|F8WF32_HUMAN" 2 1441.6197 1.26 62202 9750 2 1441.617138 721.8171 Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit 1 OS=Homo sapiens OX=9606 GN=RPN1 PE=1 SV=1 3.83 2080.8 - 1.94E+06 - - - -1.7432 - 2.905 0.557 - 979.4 1 2 0 -0.0025 12 0 0 0 8.12E+07 6.43E+07 - - - 5.9602 1 221125_WJC_METTL3_EV_vs_WT_F05.09753.09753.2 1.03E-07 15/26 K.IVIGYQSHADTATK.S "sp|P06730|IF4E_HUMAN,tr|D6RBW1|D6RBW1_HUMAN" 2 1502.7729 1.68 62203 9753 2 1502.770582 752.3937 Eukaryotic translation initiation factor 4E OS=Homo sapiens OX=9606 GN=EIF4E PE=1 SV=2 6.74 2081.2 - 1.58E+06 - - - -1.5478 - 2.79 0.562 - 549 1 2 0 -0.0023 14 0 0 0 3.80E+07 2.26E+07 - - - 5.766 0.9991 221125_WJC_METTL3_EV_vs_WT_F05.09754.09754.2 0.00804 14-Sep K.NFQLNQDK[136.11].M sp|Q9Y244|POMP_HUMAN 1 1013.5022 1.68 62204 9754 2 1013.501784 507.7584 Proteasome maturation protein OS=Homo sapiens OX=9606 GN=POMP PE=1 SV=1 5.84 2081.3 - 2.00E+06 - - - -0.37 - 1.433 0.322 - 341.8 1 2 0 -0.0004 8 0 0 0 1.88E+08 1.12E+08 - - - 2.5042 1 221125_WJC_METTL3_EV_vs_WT_F05.09756.09756.3 9.59E-08 16/48 R.LHPELSGPGVAAK.V sp|Q6DD87|ZN787_HUMAN 1 1274.6983 0.82 62206 9756 3 1274.697495 425.9067 Zinc finger protein 787 OS=Homo sapiens OX=9606 GN=ZNF787 PE=1 SV=4 6.75 2081.6 - 848525 - - - -0.6205 - 2.68 0.516 - 411.9 1 2 0 -0.0008 13 0 0 0 1.23E+07 1.50E+07 - - - 6.9655 0.9998 221125_WJC_METTL3_EV_vs_WT_F05.09759.09759.2 0.000142 13/18 R.YPDGIISK[136.11]PK[136.11].N sp|Q86U44|MTA70_HUMAN 1 1132.6463 0 62207 9759 2 1132.644103 567.3304 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 8.5 2082 - 6.20E+08 - - - -1.9485 - 2.203 0.567 - 639.5 1 2 0 -0.0022 10 0 0 0 2.54E+08 1.80E+11 - - - 5.4328 0.9999 221125_WJC_METTL3_EV_vs_WT_F05.09764.09764.3 0.00108 17/44 R.FLPAVSDENSKR.L "sp|P46087|NOP2_HUMAN,tr|F5H5X6|F5H5X6_HUMAN,tr|F5H359|F5H359_HUMAN,tr|F5H8G6|F5H8G6_HUMAN,tr|F5GWB7|F5GWB7_HUMAN,tr|F5H709|F5H709_HUMAN" 6 1361.6939 0.89 62212 9764 3 1361.689828 454.9053 Probable 28S rRNA (cytosine(4447)-C(5))-methyltransferase OS=Homo sapiens OX=9606 GN=NOP2 PE=1 SV=2 6.07 2082.5 - 1.36E+06 - - - -3.0117 - 3.401 0.481 - 411.3 1 2 0 -0.0041 12 0 0 0 2.05E+07 2.32E+07 - - - 7.2945 0.9997 221125_WJC_METTL3_EV_vs_WT_F05.09778.09778.2 9.81E-05 20-Dec R.QQSEISAAVER[166.11].A "sp|Q9Y520|PRC2C_HUMAN,tr|A0A0A0MS30|A0A0A0MS30_HUMAN,tr|E7EPN9|E7EPN9_HUMAN" 3 1226.613 1.1 62222 9778 2 1226.610649 614.3138 Protein PRRC2C OS=Homo sapiens OX=9606 GN=PRRC2C PE=1 SV=4 4.53 2084.3 - 1.39E+06 - - - -1.9574 - 2.284 0.477 - 670.9 1 2 0 -0.0024 11 0 0 0 6.41E+07 5.83E+07 - - - 4.7977 0.9998 221125_WJC_METTL3_EV_vs_WT_F05.09779.09779.2 0.00883 20-Dec R.QQSEISAAVER.A "sp|Q9Y520|PRC2C_HUMAN,tr|A0A0A0MS30|A0A0A0MS30_HUMAN,tr|E7EPN9|E7EPN9_HUMAN" 3 1216.6048 1.1 62223 9779 2 1216.60291 609.3097 Protein PRRC2C OS=Homo sapiens OX=9606 GN=PRRC2C PE=1 SV=4 4.53 2084.4 - 1.12E+06 - - - -1.5371 - 2.212 0.454 - 571.2 1 2 0 -0.0019 11 0 0 0 6.41E+07 5.83E+07 - - - 4.5413 0.9995 221125_WJC_METTL3_EV_vs_WT_F05.09780.09780.2 0.000137 16-Oct K.NDNDTFTVK.Y "sp|Q14315|FLNC_HUMAN,sp|P21333|FLNA_HUMAN,tr|A0A7P0NMY4|A0A7P0NMY4_HUMAN,tr|Q60FE5|Q60FE5_HUMAN" 4 1052.4775 1.08 62224 9780 2 1052.480109 527.246 Filamin-C OS=Homo sapiens OX=9606 GN=FLNC PE=1 SV=3 4.21 2084.6 - 1.02E+06 - - - 2.5226 - 2.001 0.481 - 433.2 1 2 0 0.0027 9 0 0 0 3.05E+07 2.82E+07 - - - 4.5996 0.9997 221125_WJC_METTL3_EV_vs_WT_F05.09781.09781.2 0.000364 16-Sep K.DFSNSPLHR.F sp|O95758|PTBP3_HUMAN 1 1071.5098 1.02 62225 9781 2 1071.507993 536.7622 Polypyrimidine tract-binding protein 3 OS=Homo sapiens OX=9606 GN=PTBP3 PE=1 SV=2 6.74 2084.7 - 909372 - - - -1.6463 - 1.721 0.486 - 303.2 1 2 0 -0.0018 9 0 0 0 2.06E+07 2.03E+07 - - - 4.2007 0.9989 221125_WJC_METTL3_EV_vs_WT_F05.09785.09785.2 0.00571 18-Aug R.STTPTSSPFR.A "sp|Q9Y520|PRC2C_HUMAN,tr|E7EPN9|E7EPN9_HUMAN,tr|A0A2R8Y424|A0A2R8Y424_HUMAN,tr|H7C5N8|H7C5N8_HUMAN,tr|A0A2R8Y7F4|A0A2R8Y7F4_HUMAN,tr|A0A2R8YET2|A0A2R8YET2_HUMAN" 6 1079.5247 2.14 62227 9785 2 1079.523048 540.7696 Protein PRRC2C OS=Homo sapiens OX=9606 GN=PRRC2C PE=1 SV=4 9.47 2085.2 - 6.89E+06 - - - -1.5655 - 1.601 0.319 - 205.8 1 2 0 -0.0017 10 0 0 0 1.22E+08 5.72E+07 - - - 2.7103 0.9997 221125_WJC_METTL3_EV_vs_WT_F05.09787.09787.2 0.000961 16-Sep R.TLLEGEESR.M sp|P04264|K2C1_HUMAN 1 1032.5088 1017.33 62229 9787 2 1032.507502 517.2617 "Keratin, type II cytoskeletal 1 OS=Homo sapiens OX=9606 GN=KRT1 PE=1 SV=6" 4.25 2085.3 - 7.52E+06 - - - -1.2126 - 1.603 0.451 - 274.5 1 2 0 -0.0013 9 0 0 0 1.90E+08 1.87E+05 - - - 3.7369 0.9997 221125_WJC_METTL3_EV_vs_WT_F05.09790.09790.2 0.000135 16-Sep K.NDNDTFTVK[136.11].Y "sp|Q14315|FLNC_HUMAN,sp|P21333|FLNA_HUMAN,tr|A0A7P0NMY4|A0A7P0NMY4_HUMAN,tr|Q60FE5|Q60FE5_HUMAN" 4 1060.4917 1.08 62232 9790 2 1060.489377 531.2531 Filamin-C OS=Homo sapiens OX=9606 GN=FLNC PE=1 SV=3 4.21 2085.7 - 1.60E+06 - - - -2.1471 - 1.985 0.48 - 329.8 1 2 0 -0.0023 9 0 0 0 3.04E+07 2.82E+07 - - - 4.5691 0.9992 221125_WJC_METTL3_EV_vs_WT_F05.09791.09791.3 0.0121 Oct-32 K.TFFHQENVR.A sp|Q9H089|LSG1_HUMAN 1 1176.5676 1.19 62233 9791 3 1176.565981 393.1965 Large subunit GTPase 1 homolog OS=Homo sapiens OX=9606 GN=LSG1 PE=1 SV=2 6.41 2085.7 - 1.52E+06 - - - -1.3811 - 1.726 0.31 - 160.4 1 2 0 -0.0016 9 0 0 0 3.38E+07 2.85E+07 - - - 3.6407 0.9884 221125_WJC_METTL3_EV_vs_WT_F05.09794.09794.2 8.57E-05 16-Sep Y.PDGIISK[136.11]PK[136.11].N sp|Q86U44|MTA70_HUMAN 1 969.583 0 62235 9794 2 969.581832 485.7988 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 9.01 2086.1 - 5.38E+07 - - - -1.1861 - 1.982 0.472 - 248 1 1 0 -0.0011 9 0 0 0 1.11E+06 2.96E+10 - - - 4.506 0.9996 221125_WJC_METTL3_EV_vs_WT_F05.09797.09797.2 0.00409 20-Sep K.QEGGDNDLIER[166.11].L "sp|P30566|PUR8_HUMAN,tr|A0A096LNY5|A0A096LNY5_HUMAN,tr|A0A1B0GTJ7|A0A1B0GTJ7_HUMAN,tr|A0A1B0GWJ0|A0A1B0GWJ0_HUMAN,tr|A0A0A6YY92|A0A0A6YY92_HUMAN,tr|A0A7P0T8E4|A0A7P0T8E4_HUMAN,tr|A0A7P0T9A7|A0A7P0T9A7_HUMAN,tr|A0A096LNY6|A0A096LNY6_HUMAN,tr|A0A7P0Z472|A0A7P0Z472_HUMAN" 9 1254.5716 0.88 62238 9797 2 1254.572615 628.2931 Adenylosuccinate lyase OS=Homo sapiens OX=9606 GN=ADSL PE=1 SV=2 3.92 2086.3 - 1.81E+06 - - - 0.8258 - 1.545 0.432 - 218.8 1 2 0 0.001 11 0 0 0 6.08E+07 6.94E+07 - - - 3.4083 0.9999 221125_WJC_METTL3_EV_vs_WT_F05.09798.09798.2 1.67E-05 22-Dec K.MDSTANEVEAVK[136.11].V "sp|P07237|PDIA1_HUMAN,tr|A0A7P0TA97|A0A7P0TA97_HUMAN,tr|A0A7P0T8C0|A0A7P0T8C0_HUMAN,tr|H7BZ94|H7BZ94_HUMAN,tr|B3KTQ9|B3KTQ9_HUMAN,tr|A0A7P0TA71|A0A7P0TA71_HUMAN,tr|I3L4M2|I3L4M2_HUMAN,tr|A0A7P0T9K9|A0A7P0T9K9_HUMAN,tr|H0Y3Z3|H0Y3Z3_HUMAN,tr|A0A7P0TA35|A0A7P0TA35_HUMAN,tr|A0A7P0TB26|A0A7P0TB26_HUMAN,tr|I3L0S0|I3L0S0_HUMAN,tr|I3L3P5|I3L3P5_HUMAN,tr|A0A7P0T8J3|A0A7P0T8J3_HUMAN,tr|A0A7P0T8X1|A0A7P0T8X1_HUMAN" 15 1300.606 1.21 62239 9798 2 1300.605568 651.3103 Protein disulfide-isomerase OS=Homo sapiens OX=9606 GN=P4HB PE=1 SV=3 4.14 2086.4 - 832106 - - - -0.3568 - 2.03 0.492 - 264.2 1 2 0 -0.0005 12 0 0 0 2.28E+07 1.88E+07 - - - 4.5377 0.9997 221125_WJC_METTL3_EV_vs_WT_F05.09803.09803.2 0.000361 22-Aug K.VYVGNLGNNGNK.T "sp|P84103|SRSF3_HUMAN,tr|A0A087X2D0|A0A087X2D0_HUMAN" 2 1247.6258 1.26 62242 9803 2 1247.62486 624.8202 Serine\arginine-rich splicing factor 3 OS=Homo sapiens OX=9606 GN=SRSF3 PE=1 SV=1 8.56 2087.1 - 3.32E+06 - - - -0.7927 - 1.738 0.442 - 158.9 1 2 0 -0.001 12 0 0 0 1.78E+08 1.42E+08 - - - 3.7596 0.9996 221125_WJC_METTL3_EV_vs_WT_F05.09804.09804.2 3.33E-05 22-Sep K.VYVGNLGNNGNK[136.11].T "sp|P84103|SRSF3_HUMAN,tr|A0A087X2D0|A0A087X2D0_HUMAN" 2 1255.64 1.26 62243 9804 2 1255.638865 628.8273 Serine\arginine-rich splicing factor 3 OS=Homo sapiens OX=9606 GN=SRSF3 PE=1 SV=1 8.56 2087.1 - 2.81E+06 - - - -0.9429 - 1.696 0.417 - 191.5 1 2 0 -0.0012 12 0 0 0 1.77E+08 1.40E+08 - - - 3.5106 0.9919 221125_WJC_METTL3_EV_vs_WT_F05.09805.09805.2 0.00785 16/26 A.GGPGPGGFGAQGPK.G "sp|P0DMV8|HS71A_HUMAN,sp|P0DMV9|HS71B_HUMAN,tr|V9GZ37|V9GZ37_HUMAN,tr|A0A0G2JIW1|A0A0G2JIW1_HUMAN" 4 1182.5782 0.12 62244 9805 2 1182.577088 592.2964 Heat shock 70 kDa protein 1A OS=Homo sapiens OX=9606 GN=HSPA1A PE=1 SV=1 8.75 2087.2 - 1.23E+06 - - - -0.9158 - 2.694 0.458 - 934.8 1 1 0 -0.0011 14 0 0 0 1.25E+08 1.06E+09 - - - 4.9104 0.9981 221125_WJC_METTL3_EV_vs_WT_F05.09806.09806.3 0.134 Jun-32 R.YC[160.03]DAVFHER.Y "sp|P49711|CTCF_HUMAN,tr|A0A2R8YFL0|A0A2R8YFL0_HUMAN,tr|A0A2R8Y595|A0A2R8Y595_HUMAN" 3 1195.508 1.5 62245 9806 3 1195.507965 399.51 Transcriptional repressor CTCF OS=Homo sapiens OX=9606 GN=CTCF PE=1 SV=1 5.32 2087.3 - 793601 - - - -0.0652 - 1.428 0.312 - 31.2 3 2 0 -0.0001 9 0 0 0 1.23E+07 8.23E+06 - - - 2.8714 0.9857 221125_WJC_METTL3_EV_vs_WT_F05.09809.09809.2 0.000156 22-Aug L.LSQTQGPPDYPR[166.11].F "sp|Q13405|RM49_HUMAN,tr|E9PNF1|E9PNF1_HUMAN,tr|E9PI78|E9PI78_HUMAN" 3 1367.6709 2.45 62248 9809 2 1367.672008 684.8427 "39S ribosomal protein L49, mitochondrial OS=Homo sapiens OX=9606 GN=MRPL49 PE=1 SV=1" 5.84 2087.7 - 410597 - - - 0.8109 - 1.863 0.462 - 225.2 1 1 0 0.0011 12 0 0 0 1.53E+07 6.25E+06 - - - 4.0901 0.9996 221125_WJC_METTL3_EV_vs_WT_F05.09810.09810.2 0.017 22-Aug R.SPPPGMGLNQNR.G sp|P23246|SFPQ_HUMAN 1 1266.6139 0.33 62249 9810 2 1266.614804 634.3142 "Splicing factor, proline- and glutamine-rich OS=Homo sapiens OX=9606 GN=SFPQ PE=1 SV=2" 9.47 2087.8 - 312148 - - - 0.7106 - 1.768 0.403 - 199.7 1 2 0 0.0009 12 0 0 0 6.55E+06 2.01E+07 - - - 3.5166 0.9982 221125_WJC_METTL3_EV_vs_WT_F05.09814.09814.2 0.036 14-May K.NFQLNQDK.M sp|Q9Y244|POMP_HUMAN 1 1005.488 1.68 62251 9814 2 1005.487638 503.7513 Proteasome maturation protein OS=Homo sapiens OX=9606 GN=POMP PE=1 SV=1 5.84 2088.4 - 1.18E+07 - - - -0.3192 - 1.406 0.263 - 78.6 2 2 0 -0.0003 8 0 0 0 1.88E+08 1.12E+08 - - - 1.8766 0.9963 221125_WJC_METTL3_EV_vs_WT_F05.09815.09815.2 8.87E-05 24-Nov K.TTPEC[160.03]GPTGYVEK.L sp|O76095|JTB_HUMAN 1 1437.6446 1.47 62252 9815 2 1437.637604 719.8296 Protein JTB OS=Homo sapiens OX=9606 GN=JTB PE=1 SV=1 4.53 2088.5 - 765437 - - - -4.8635 - 1.832 0.461 - 271.1 1 2 0 -0.007 13 0 0 0 1.23E+07 8.34E+06 - - - 3.9975 0.998 221125_WJC_METTL3_EV_vs_WT_F05.09816.09816.2 0.000284 18-Oct R.K[136.11]FADIGNTVK[136.11].K "sp|P11172|UMPS_HUMAN,tr|E9PFD2|E9PFD2_HUMAN" 2 1107.6259 0.67 62253 9816 2 1107.622251 554.8202 Uridine 5'-monophosphate synthase OS=Homo sapiens OX=9606 GN=UMPS PE=1 SV=1 8.59 2088.6 - 530619 - - - -3.3026 - 1.812 0.359 - 267.4 1 2 0 -0.0037 10 0 0 0 4.92E+06 7.36E+06 - - - 3.3507 0.9999 221125_WJC_METTL3_EV_vs_WT_F05.09820.09820.2 4.16 13/18 R.YPDGIISK[136.11]PK.N sp|Q86U44|MTA70_HUMAN 1 1124.6321 - 62256 9820 2 1124.63165 563.3233 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 8.5 2089.1 - 1.90E+06 - - - -0.409 - 2.315 0.532 - 622.3 1 2 0 -0.0005 10 0 0 0 - - - - - 5.3133 0.9992 221125_WJC_METTL3_EV_vs_WT_F05.09822.09822.2 0.0212 18-Nov R.K[136.11]QESTVMVLR[166.11].N "sp|Q9UHX1|PUF60_HUMAN,tr|A0A0J9YYL3|A0A0J9YYL3_HUMAN,tr|A0A0J9YXX5|A0A0J9YXX5_HUMAN,tr|A0A0J9YXJ8|A0A0J9YXJ8_HUMAN,tr|A0A0J9YVP6|A0A0J9YVP6_HUMAN" 5 1207.6714 1.18 62257 9822 2 1207.674431 604.843 Poly(U)-binding-splicing factor PUF60 OS=Homo sapiens OX=9606 GN=PUF60 PE=1 SV=1 8.75 2089.3 - 698886 - - - 2.5404 - 2.277 0.34 - 451.9 1 2 0 0.0031 10 0 0 0 1.32E+07 1.12E+07 - - - 3.8481 0.9991 221125_WJC_METTL3_EV_vs_WT_F05.09823.09823.2 8.30E-05 20-Oct R.NFSDNQLQEGK.N "sp|P37802|TAGL2_HUMAN,tr|X6RJP6|X6RJP6_HUMAN" 2 1278.584 1.06 62258 9823 2 1278.580746 640.2993 Transgelin-2 OS=Homo sapiens OX=9606 GN=TAGLN2 PE=1 SV=3 4.37 2089.4 - 705655 - - - -2.5794 - 1.948 0.383 - 300.6 1 2 0 -0.0033 11 0 0 0 6.58E+06 6.20E+06 - - - 3.6727 0.9997 221125_WJC_METTL3_EV_vs_WT_F05.09824.09824.3 0.000316 Sep-36 R.KQESTVMVLR.N "sp|Q9UHX1|PUF60_HUMAN,tr|A0A0J9YYL3|A0A0J9YYL3_HUMAN,tr|A0A0J9YXX5|A0A0J9YXX5_HUMAN,tr|A0A0J9YXJ8|A0A0J9YXJ8_HUMAN,tr|A0A0J9YVP6|A0A0J9YVP6_HUMAN" 5 1189.6489 1.24 62259 9824 3 1189.648104 397.5569 Poly(U)-binding-splicing factor PUF60 OS=Homo sapiens OX=9606 GN=PUF60 PE=1 SV=1 8.75 2089.5 - 2.61E+06 - - - -0.6632 - 1.909 0.336 - 133.3 1 2 0 -0.0008 10 0 0 0 4.76E+07 3.84E+07 - - - 4.1741 0.9998 221125_WJC_METTL3_EV_vs_WT_F05.09825.09825.2 0.000511 20-Sep K.LQVSQQEDITK.S "sp|P29218|IMPA1_HUMAN,tr|E5RG13|E5RG13_HUMAN,tr|H0YBL1|H0YBL1_HUMAN,tr|E5RIP7|E5RIP7_HUMAN" 4 1287.667 1.85 62260 9825 2 1287.666696 644.8408 Inositol monophosphatase 1 OS=Homo sapiens OX=9606 GN=IMPA1 PE=1 SV=1 4.37 2089.6 - 634166 - - - -0.271 - 2.005 0.48 - 260.8 1 2 0 -0.0003 11 0 0 0 6.07E+06 3.29E+06 - - - 4.4681 0.9993 221125_WJC_METTL3_EV_vs_WT_F05.09826.09826.2 1.05E-06 24-Dec K.TTPEC[160.03]GPTGYVEK[136.11].L sp|O76095|JTB_HUMAN 1 1445.6588 1.47 62261 9826 2 1445.654094 723.8367 Protein JTB OS=Homo sapiens OX=9606 GN=JTB PE=1 SV=1 4.53 2089.8 - 621344 - - - -3.2525 - 2.283 0.494 - 507.8 1 2 0 -0.0047 13 0 0 0 1.23E+07 8.34E+06 - - - 4.8069 0.9994 221125_WJC_METTL3_EV_vs_WT_F05.09827.09827.3 0.00494 Nov-40 K.C[160.03]EAVIGHFNGK[136.11].F "sp|P29558|RBMS1_HUMAN,tr|E7ETU5|E7ETU5_HUMAN,tr|F6Y5H0|F6Y5H0_HUMAN" 3 1238.5957 2.27 62262 9827 3 1238.593448 413.8725 "RNA-binding motif, single-stranded-interacting protein 1 OS=Homo sapiens OX=9606 GN=RBMS1 PE=1 SV=3" 6.74 2089.9 - 518456 - - - -1.8521 - 1.863 0.337 - 124.3 1 2 0 -0.0023 11 0 0 0 1.15E+07 5.08E+06 - - - 4.0641 0.9732 221125_WJC_METTL3_EV_vs_WT_F05.09828.09828.3 0.169 Jul-40 R.YFDTAVSRPGR.G "sp|P10321|HLAC_HUMAN,tr|A0A140T921|A0A140T921_HUMAN,tr|A0A140T942|A0A140T942_HUMAN,tr|F8W9Z8|F8W9Z8_HUMAN,tr|A0A140TA05|A0A140TA05_HUMAN,tr|O19617|O19617_HUMAN,tr|A0A140T9E1|A0A140T9E1_HUMAN,tr|A0A140T9Z7|A0A140T9Z7_HUMAN,tr|A2AEA2|A2AEA2_HUMAN,tr|A0A140T9H5|A0A140T9H5_HUMAN,tr|Q5QT33|Q5QT33_HUMAN,tr|A0A140T9J9|A0A140T9J9_HUMAN,tr|A0A140T9L3|A0A140T9L3_HUMAN,tr|A0A140T9B3|A0A140T9B3_HUMAN,tr|A0A140T962|A0A140T962_HUMAN,tr|A0A140T9U8|A0A140T9U8_HUMAN,tr|A0A140TA12|A0A140TA12_HUMAN,tr|A0A1W2PR11|A0A1W2PR11_HUMAN" 18 1267.6309 1.5 62263 9828 3 1267.629465 423.5509 "HLA class I histocompatibility antigen, C alpha chain OS=Homo sapiens OX=9606 GN=HLA-C PE=1 SV=3" 8.75 2090 - 393676 - - - -1.1596 - 1.299 0.19 - 55.8 2 2 0 -0.0015 11 0 0 0 6.85E+06 4.58E+06 - - - 1.2617 1 221125_WJC_METTL3_EV_vs_WT_F05.09829.09829.2 1.06E-05 26-Dec R.IAEC[160.03]SSQLAEEEEK.A sp|P35580|MYH10_HUMAN 1 1621.7141 1.03 62264 9829 2 1621.716498 811.8643 Myosin-10 OS=Homo sapiens OX=9606 GN=MYH10 PE=1 SV=3 3.98 2090.1 - 192283 - - - 1.459 - 2.609 0.584 - 496.7 1 2 0 0.0024 14 0 0 0 5.32E+06 5.16E+06 - - - 5.7602 0.9982 221125_WJC_METTL3_EV_vs_WT_F05.09830.09830.2 0.00155 26-Oct R.SLLEGEGSSGGGGR.G "sp|P13645|K1C10_HUMAN,tr|A0A1B0GVI3|A0A1B0GVI3_HUMAN" 2 1261.5899 224.85 62265 9830 2 1261.592541 631.8022 "Keratin, type I cytoskeletal 10 OS=Homo sapiens OX=9606 GN=KRT10 PE=1 SV=6" 4.53 2090.3 - 521055 - - - 2.1267 - 1.557 0.345 - 172.9 1 2 0 0.0027 14 0 0 0 8.65E+06 3.85E+04 - - - 2.6994 1 221125_WJC_METTL3_EV_vs_WT_F05.09831.09831.2 1.58E-06 26-Dec R.IAEC[160.03]SSQLAEEEEK[136.11].A sp|P35580|MYH10_HUMAN 1 1629.7283 1.03 62266 9831 2 1629.726401 815.8714 Myosin-10 OS=Homo sapiens OX=9606 GN=MYH10 PE=1 SV=3 3.98 2090.4 - 173225 - - - -1.1849 - 2.731 0.636 - 527.6 1 2 0 -0.0019 14 0 0 0 5.32E+06 5.16E+06 - - - 6.2591 0.9759 221125_WJC_METTL3_EV_vs_WT_F05.09834.09834.2 0.000291 16-Sep Y.PDGIISKPK[136.11].N sp|Q86U44|MTA70_HUMAN 1 961.5688 - 62268 9834 2 961.568458 481.7917 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 9.01 2090.8 - 394837 - - - -0.3369 - 1.701 0.359 - 231.7 1 1 0 -0.0003 9 0 0 0 - - - - - 3.2293 0.9696 221125_WJC_METTL3_EV_vs_WT_F05.09835.09835.3 0.358 Aug-44 R.EVEEEPGIHSLK[136.11].H "sp|Q9Y4L1|HYOU1_HUMAN,tr|A0A087WWI4|A0A087WWI4_HUMAN,tr|K7EQK2|K7EQK2_HUMAN,tr|A0A494C039|A0A494C039_HUMAN,tr|A0A087X054|A0A087X054_HUMAN,tr|E9PJ21|E9PJ21_HUMAN" 6 1373.6918 1.26 62269 9835 3 1373.692815 458.9045 Hypoxia up-regulated protein 1 OS=Homo sapiens OX=9606 GN=HYOU1 PE=1 SV=1 4.48 2091 - 616749 - - - 0.7316 - 1.395 0.151 - 73.9 1 2 0 0.001 12 0 0 0 1.29E+07 1.02E+07 - - - 1.146 0.999 221125_WJC_METTL3_EV_vs_WT_F05.09836.09836.2 0.0145 18-Jun K.QADVNLVNAK.L "sp|O43175|SERA_HUMAN,tr|A0A2C9F2M7|A0A2C9F2M7_HUMAN,tr|A0A286YF22|A0A286YF22_HUMAN" 3 1070.572 2.58 62270 9836 2 1070.572486 536.2933 D-3-phosphoglycerate dehydrogenase OS=Homo sapiens OX=9606 GN=PHGDH PE=1 SV=4 5.84 2091.1 - 357985 - - - 0.4325 - 1.519 0.315 - 89.8 2 2 0 0.0005 10 0 0 0 8.60E+06 3.33E+06 - - - 2.3999 0.9197 221125_WJC_METTL3_EV_vs_WT_F05.09838.09838.2 0.00774 24-Jul L.ILHDDEVTVTEDK.L sp|P05386|RLA1_HUMAN 1 1512.7308 1.03 62272 9838 2 1512.73248 757.3727 60S acidic ribosomal protein P1 OS=Homo sapiens OX=9606 GN=RPLP1 PE=1 SV=1 4.1 2091.4 - 250314 - - - 1.1317 - 1.468 0.314 - 126.1 1 1 0 0.0017 13 0 0 0 2.17E+06 2.11E+06 - - - 2.345 0.9265 221125_WJC_METTL3_EV_vs_WT_F05.09839.09839.2 0.00561 26-Aug K.VYAVATSTNTPC[160.03]AR[166.11].L sp|Q10570|CPSF1_HUMAN 1 1519.7328 0.29 62273 9839 2 1520.738936 760.8737 Cleavage and polyadenylation specificity factor subunit 1 OS=Homo sapiens OX=9606 GN=CPSF1 PE=1 SV=2 8.19 2091.5 - 196068 - - - 662.017 - 1.814 0.298 - 178.1 1 2 0 1.0061 14 0 0 0 5.88E+05 2.01E+06 - - - 2.4206 0.9999 221125_WJC_METTL3_EV_vs_WT_F05.09842.09842.3 6.51E-05 Dec-48 R.GLPPHTTDQDLVK.L "sp|P29558|RBMS1_HUMAN,tr|E7ETU5|E7ETU5_HUMAN,tr|F6Y5H0|F6Y5H0_HUMAN,tr|E7EPF2|E7EPF2_HUMAN" 4 1419.7358 1.93 62274 9842 3 1419.736689 474.2525 "RNA-binding motif, single-stranded-interacting protein 1 OS=Homo sapiens OX=9606 GN=RBMS1 PE=1 SV=3" 5.21 2091.9 - 1.94E+06 - - - 0.6304 - 1.9 0.431 - 118 1 2 0 0.0009 13 0 0 0 2.30E+08 1.19E+08 - - - 5.0852 1 221125_WJC_METTL3_EV_vs_WT_F05.09843.09843.2 1.30E-05 17/18 R.HVVLGAIENK[136.11].V sp|P41227|NAA10_HUMAN 1 1086.6277 0.36 62275 9843 2 1086.628525 544.3211 N-alpha-acetyltransferase 10 OS=Homo sapiens OX=9606 GN=NAA10 PE=1 SV=1 6.75 2092 - 1.09E+06 - - - 0.7648 - 3.05 0.524 - 1087.6 1 2 0 0.0008 10 0 0 0 5.28E+06 1.48E+07 - - - 6.0237 0.9941 221125_WJC_METTL3_EV_vs_WT_F05.09844.09844.3 0.0633 Oct-36 R.TDK[136.11]ELIATVR[166.11].R "sp|Q14254|FLOT2_HUMAN,tr|E7EMK3|E7EMK3_HUMAN,tr|K7EKW9|K7EKW9_HUMAN,tr|J3QLD9|J3QLD9_HUMAN" 4 1162.6677 1.76 62276 9844 3 1162.667156 388.5632 Flotillin-2 OS=Homo sapiens OX=9606 GN=FLOT2 PE=1 SV=2 5.74 2092.1 - 1.47E+06 - - - -0.4318 - 1.832 0.253 - 97 1 2 1 -0.0005 10 0 0 0 2.33E+07 1.32E+07 - - - 3.1286 0.9999 221125_WJC_METTL3_EV_vs_WT_F05.09845.09845.3 0.000122 13/48 R.GLPPHTTDQDLVK[136.11].L "sp|P29558|RBMS1_HUMAN,tr|E7ETU5|E7ETU5_HUMAN,tr|F6Y5H0|F6Y5H0_HUMAN,tr|E7EPF2|E7EPF2_HUMAN" 4 1427.75 1.94 62277 9845 3 1427.750572 476.9239 "RNA-binding motif, single-stranded-interacting protein 1 OS=Homo sapiens OX=9606 GN=RBMS1 PE=1 SV=3" 5.21 2092.1 - 1.37E+06 - - - 0.4048 - 2.231 0.436 - 152.6 1 2 0 0.0006 13 0 0 0 2.30E+08 1.19E+08 - - - 5.5765 0.9999 221125_WJC_METTL3_EV_vs_WT_F05.09846.09846.2 3.04E-05 14/18 R.HVVLGAIENK.V sp|P41227|NAA10_HUMAN 1 1078.6135 0.23 62278 9846 2 1078.614065 540.314 N-alpha-acetyltransferase 10 OS=Homo sapiens OX=9606 GN=NAA10 PE=1 SV=1 6.75 2092.3 - 622812 - - - 0.5294 - 2.528 0.532 - 682.5 1 2 0 0.0006 10 0 0 0 5.69E+06 2.48E+07 - - - 5.5589 0.946 221125_WJC_METTL3_EV_vs_WT_F05.09850.09850.3 0.347 Jun-40 R.YFDTAVSR[166.11]PGR[166.11].G "sp|P10321|HLAC_HUMAN,tr|A0A140T921|A0A140T921_HUMAN,tr|A0A140T942|A0A140T942_HUMAN,tr|F8W9Z8|F8W9Z8_HUMAN,tr|A0A140TA05|A0A140TA05_HUMAN,tr|O19617|O19617_HUMAN,tr|A0A140T9E1|A0A140T9E1_HUMAN,tr|A0A140T9Z7|A0A140T9Z7_HUMAN,tr|A2AEA2|A2AEA2_HUMAN,tr|A0A140T9H5|A0A140T9H5_HUMAN,tr|Q5QT33|Q5QT33_HUMAN,tr|A0A140T9J9|A0A140T9J9_HUMAN,tr|A0A140T9L3|A0A140T9L3_HUMAN,tr|A0A140T9B3|A0A140T9B3_HUMAN,tr|A0A140T962|A0A140T962_HUMAN,tr|A0A140T9U8|A0A140T9U8_HUMAN,tr|A0A140TA12|A0A140TA12_HUMAN,tr|A0A1W2PR11|A0A1W2PR11_HUMAN" 18 1287.6475 2.26 62282 9850 3 1287.649134 430.2231 "HLA class I histocompatibility antigen, C alpha chain OS=Homo sapiens OX=9606 GN=HLA-C PE=1 SV=3" 8.75 2092.7 - 382503 - - - 1.2884 - 1.268 0.168 - 36.7 2 2 0 0.0017 11 0 0 0 9.36E+06 4.14E+06 - - - 0.9478 0.9983 221125_WJC_METTL3_EV_vs_WT_F05.09851.09851.2 9.78E-05 18-Nov R.TDKELIATVR.R "sp|Q14254|FLOT2_HUMAN,tr|E7EMK3|E7EMK3_HUMAN,tr|K7EKW9|K7EKW9_HUMAN,tr|J3QLD9|J3QLD9_HUMAN" 4 1144.6452 1.45 62283 9851 2 1144.646357 573.3299 Flotillin-2 OS=Homo sapiens OX=9606 GN=FLOT2 PE=1 SV=2 5.74 2092.9 - 368881 - - - 1.0213 - 2.246 0.503 - 412.2 1 2 1 0.0012 10 0 0 0 3.30E+06 2.28E+06 - - - 5.0144 0.8947 221125_WJC_METTL3_EV_vs_WT_F05.09852.09852.3 0.443 Aug-44 K.VYVGNLGNNGNK[136.11].T "sp|P84103|SRSF3_HUMAN,tr|A0A087X2D0|A0A087X2D0_HUMAN" 2 1255.64 1.56 62284 9852 3 1255.637889 419.554 Serine\arginine-rich splicing factor 3 OS=Homo sapiens OX=9606 GN=SRSF3 PE=1 SV=1 8.56 2093 - 263872 - - - -1.7202 - 1.252 0.132 - 76 1 2 0 -0.0022 12 0 0 0 3.69E+06 2.37E+06 - - - 0.634 0.9999 221125_WJC_METTL3_EV_vs_WT_F05.09853.09853.2 0.000311 24-Dec K.GPGEVAGTVTGQK[136.11].R "sp|Q86U44|MTA70_HUMAN,tr|F5H6D8|F5H6D8_HUMAN,tr|H0YFV6|H0YFV6_HUMAN,tr|B4DTN4|B4DTN4_HUMAN" 4 1207.6288 0.48 62285 9853 2 1207.6286 604.8217 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 6 2093.1 - 252625 - - - -0.1789 - 2.407 0.551 - 564.7 1 2 0 -0.0002 13 0 0 0 7.32E+06 1.52E+07 - - - 5.365 0.9987 221125_WJC_METTL3_EV_vs_WT_F05.09860.09860.3 0.0245 Oct-44 R.EVEEEPGIHSLK.H "sp|Q9Y4L1|HYOU1_HUMAN,tr|A0A087WWI4|A0A087WWI4_HUMAN,tr|K7EQK2|K7EQK2_HUMAN,tr|A0A494C039|A0A494C039_HUMAN,tr|A0A087X054|A0A087X054_HUMAN,tr|E9PJ21|E9PJ21_HUMAN" 6 1365.6776 1.26 62291 9860 3 1365.676547 456.2331 Hypoxia up-regulated protein 1 OS=Homo sapiens OX=9606 GN=HYOU1 PE=1 SV=1 4.48 2094 - 541156 - - - -0.7784 - 1.568 0.301 - 81.9 1 2 0 -0.0011 12 0 0 0 1.29E+07 1.02E+07 - - - 3.1423 0.9592 221125_WJC_METTL3_EV_vs_WT_F05.09863.09863.2 1.42E-05 22-Nov L.LSQTQGPPDYPR.F "sp|Q13405|RM49_HUMAN,tr|E9PNF1|E9PNF1_HUMAN,tr|E9PI78|E9PI78_HUMAN" 3 1357.6626 2.36 62294 9863 2 1357.662783 679.8386 "39S ribosomal protein L49, mitochondrial OS=Homo sapiens OX=9606 GN=MRPL49 PE=1 SV=1" 5.84 2094.3 - 736871 - - - 0.1134 - 2.165 0.219 - 394.8 1 1 0 0.0002 12 0 0 0 1.47E+07 6.25E+06 - - - 2.6909 0.9986 221125_WJC_METTL3_EV_vs_WT_F05.09864.09864.2 0.000257 20-Nov K.GTNIQENEYVK[136.11].M sp|Q9BRX2|PELO_HUMAN 1 1301.6343 0.63 62295 9864 2 1301.639547 651.8244 Protein pelota homolog OS=Homo sapiens OX=9606 GN=PELO PE=1 SV=2 4.53 2094.4 - 722345 - - - 4.0349 - 2.311 0.45 - 553.7 1 2 0 0.0053 11 0 0 0 2.97E+06 4.70E+06 - - - 4.6292 0.9985 221125_WJC_METTL3_EV_vs_WT_F05.09866.09866.2 4.12E-05 20-Oct K.GTNIQENEYVK.M sp|Q9BRX2|PELO_HUMAN 1 1293.6201 0.63 62297 9866 2 1293.624704 647.8173 Protein pelota homolog OS=Homo sapiens OX=9606 GN=PELO PE=1 SV=2 4.53 2094.6 - 583396 - - - 3.5629 - 2.197 0.376 - 529.9 1 2 0 0.0046 11 0 0 0 2.97E+06 4.70E+06 - - - 3.946 0.9983 221125_WJC_METTL3_EV_vs_WT_F05.09867.09867.2 0.00109 18-Oct K.SSVLPSPSGR.S "sp|P35658|NU214_HUMAN,tr|A0A0A0MSW3|A0A0A0MSW3_HUMAN,tr|A0A494BZU9|A0A494BZU9_HUMAN,tr|A0A494C1F2|A0A494C1F2_HUMAN" 4 985.5193 0.23 62298 9867 2 985.522183 493.7669 Nuclear pore complex protein Nup214 OS=Homo sapiens OX=9606 GN=NUP214 PE=1 SV=2 9.47 2094.7 - 538285 - - - 2.967 - 1.618 0.399 - 281.4 1 2 0 0.0029 10 0 0 0 5.07E+06 2.24E+07 - - - 3.3302 0.924 221125_WJC_METTL3_EV_vs_WT_F05.09869.09869.3 2.39 Aug-44 K.VYVGNLGNNGNK.T "sp|P84103|SRSF3_HUMAN,tr|A0A087X2D0|A0A087X2D0_HUMAN" 2 1247.6258 1.38 62300 9869 3 1247.62733 416.8826 Serine\arginine-rich splicing factor 3 OS=Homo sapiens OX=9606 GN=SRSF3 PE=1 SV=1 8.56 2094.9 - 377174 - - - 1.1871 - 1.313 0.14 - 75.6 2 2 0 0.0015 12 0 0 0 3.80E+06 2.76E+06 - - - 0.7159 0.9793 221125_WJC_METTL3_EV_vs_WT_F05.09870.09870.2 2.78E-05 22-Oct A.SSLGGGFGGGSR.G sp|P35527|K1C9_HUMAN 1 1037.489 999 62301 9870 2 1037.4911 519.7518 "Keratin, type I cytoskeletal 9 OS=Homo sapiens OX=9606 GN=KRT9 PE=1 SV=3" 9.47 2095.1 - 355987 - - - 2.0039 - 2.015 0.487 - 233.4 1 1 0 0.0021 12 0 0 0 2.85E+07 0.00E+00 - - - 4.4808 0.9998 221125_WJC_METTL3_EV_vs_WT_F05.09871.09871.2 5.05E-07 24-Dec K.SEPIPESNDGPVK[136.11].V sp|P30101|PDIA3_HUMAN 1 1375.6711 1.09 62302 9871 2 1375.673182 688.8428 Protein disulfide-isomerase A3 OS=Homo sapiens OX=9606 GN=PDIA3 PE=1 SV=4 4.14 2095.2 - 336273 - - - 1.5316 - 2.194 0.553 - 350.9 1 2 0 0.0021 13 0 0 0 1.77E+07 1.62E+07 - - - 5.1414 0.9991 221125_WJC_METTL3_EV_vs_WT_F05.09872.09872.2 0.00109 22-Aug K.LPTPTSSVPAQK[136.11].T "sp|Q9BTA9|WAC_HUMAN,tr|A0A7P0T961|A0A7P0T961_HUMAN,tr|J3QTA0|J3QTA0_HUMAN" 3 1232.6856 2 62303 9872 2 1232.686121 617.3501 WW domain-containing adapter protein with coiled-coil OS=Homo sapiens OX=9606 GN=WAC PE=1 SV=3 8.75 2095.3 - 286254 - - - 0.4202 - 1.625 0.292 - 219.6 1 2 0 0.0005 12 0 0 0 5.31E+06 2.66E+06 - - - 2.475 1 221125_WJC_METTL3_EV_vs_WT_F05.09874.09874.2 4.17E-09 28-Dec K.APGTNVAMASNQAVR.L sp|P49792|RBP2_HUMAN 1 1485.7358 0.29 62305 9874 2 1485.737732 743.8752 E3 SUMO-protein ligase RanBP2 OS=Homo sapiens OX=9606 GN=RANBP2 PE=1 SV=2 9.79 2095.6 - 187470 - - - 1.293 - 2.66 0.642 - 359 1 2 0 0.0019 15 0 0 0 3.24E+06 1.13E+07 - - - 6.1875 0.9999 221125_WJC_METTL3_EV_vs_WT_F05.09875.09875.2 4.28E-06 26-Sep R.QTPAGPETEEEPYR.R sp|Q13505|MTX1_HUMAN 1 1602.7162 1.1 62306 9875 2 1602.71796 802.3654 Metaxin-1 OS=Homo sapiens OX=9606 GN=MTX1 PE=1 SV=3 4.09 2095.7 - 157030 - - - 1.11 - 1.897 0.644 - 219.1 1 2 0 0.0018 14 0 0 0 1.23E+06 1.12E+06 - - - 5.4038 0.9997 221125_WJC_METTL3_EV_vs_WT_F05.09880.09880.3 0.000706 16/56 K.TPHPVLTPVAANQAK.Q "sp|P35658|NU214_HUMAN,tr|A0A0A0MSW3|A0A0A0MSW3_HUMAN,tr|A0A494C1F2|A0A494C1F2_HUMAN,tr|A0A494C104|A0A494C104_HUMAN,tr|H0Y837|H0Y837_HUMAN" 5 1542.8518 3.29 62309 9880 3 1542.854152 515.2912 Nuclear pore complex protein Nup214 OS=Homo sapiens OX=9606 GN=NUP214 PE=1 SV=2 8.44 2096.4 - 1.60E+06 - - - 1.5069 - 2.548 0.323 - 284.9 1 2 0 0.0023 15 0 0 0 2.78E+07 8.46E+06 - - - 4.5811 0.9998 221125_WJC_METTL3_EV_vs_WT_F05.09881.09881.2 0.000496 20-Oct K.IYIDSNNNPER.F "sp|Q00610|CLH1_HUMAN,tr|A0A087WVQ6|A0A087WVQ6_HUMAN" 2 1333.6262 0.46 62310 9881 2 1333.628068 667.8204 Clathrin heavy chain 1 OS=Homo sapiens OX=9606 GN=CLTC PE=1 SV=5 4.37 2096.4 - 1.46E+06 - - - 1.3684 - 2.107 0.47 - 336.8 1 2 0 0.0018 11 0 0 0 7.97E+07 1.73E+08 - - - 4.528 0.9998 221125_WJC_METTL3_EV_vs_WT_F05.09882.09882.2 2.90E-07 20-Nov K.IYIDSNNNPER[166.11].F "sp|Q00610|CLH1_HUMAN,tr|A0A087WVQ6|A0A087WVQ6_HUMAN" 2 1343.6345 0.74 62311 9882 2 1343.636524 672.8245 Clathrin heavy chain 1 OS=Homo sapiens OX=9606 GN=CLTC PE=1 SV=5 4.37 2096.5 - 1.43E+06 - - - 1.4967 - 2.16 0.565 - 411.3 1 2 0 0.002 11 0 0 0 7.93E+07 1.07E+08 - - - 5.2968 1 221125_WJC_METTL3_EV_vs_WT_F05.09885.09885.3 2.96E-08 17/64 R.AMIGHTDSAEAAPGTIR[166.11].G "sp|O00746|NDKM_HUMAN,tr|Q4TT34|Q4TT34_HUMAN,tr|A0A087WVT9|A0A087WVT9_HUMAN,tr|H0Y6J0|H0Y6J0_HUMAN,tr|F2Z2X0|F2Z2X0_HUMAN" 5 1706.8285 2.17 62314 9885 3 1706.827444 569.9501 "Nucleoside diphosphate kinase, mitochondrial OS=Homo sapiens OX=9606 GN=NME4 PE=1 SV=1" 5.32 2096.7 - 1.18E+06 - - - -0.6415 - 2.98 0.539 - 270.1 1 2 0 -0.0011 17 0 0 0 2.72E+09 1.25E+09 - - - 7.3075 0.9999 221125_WJC_METTL3_EV_vs_WT_F05.09886.09886.3 0.000312 Nov-36 R.GGDLMAYDR[166.11]R[166.11].G "sp|P61978|HNRPK_HUMAN,tr|Q5T6W2|Q5T6W2_HUMAN" 2 1172.5511 1.31 62315 9886 3 1172.550811 391.8577 Heterogeneous nuclear ribonucleoprotein K OS=Homo sapiens OX=9606 GN=HNRNPK PE=1 SV=1 5.96 2096.8 - 871750 - - - -0.2729 - 2.081 0.448 - 249.4 1 2 0 -0.0003 10 0 0 0 3.41E+07 2.61E+07 - - - 5.6749 0.9636 221125_WJC_METTL3_EV_vs_WT_F05.09892.09892.3 0.00188 Oct-40 C.GLC[160.03]NQFGHEVK.D sp|Q9H0D6|XRN2_HUMAN 1 1287.603 0.72 62321 9892 3 1287.605053 430.2083 5'-3' exoribonuclease 2 OS=Homo sapiens OX=9606 GN=XRN2 PE=1 SV=1 6.74 2097.5 - 545854 - - - 1.5898 - 1.585 0.41 - 95.2 1 1 0 0.002 11 0 0 0 7.63E+06 1.06E+07 - - - 4.419 0.9976 221125_WJC_METTL3_EV_vs_WT_F05.09893.09893.2 0.0126 20-Sep R.GSQLAQEMQGK.L sp|Q9BTP7|FAP24_HUMAN 1 1175.5605 1.54 62322 9893 2 1175.559972 588.7875 Fanconi anemia core complex-associated protein 24 OS=Homo sapiens OX=9606 GN=FAAP24 PE=1 SV=2 6 2097.6 - 424931 - - - -0.4253 - 1.16 0.299 - 151.5 1 2 0 -0.0005 11 0 0 0 3.37E+06 2.19E+06 - - - 1.6508 0.9996 221125_WJC_METTL3_EV_vs_WT_F05.09895.09895.2 0.00433 13/26 K.ALSAVSAQAAAAQK.N "sp|O00268|TAF4_HUMAN,tr|V9GY14|V9GY14_HUMAN,tr|A0A0G2JRY5|A0A0G2JRY5_HUMAN" 3 1285.699 2 62324 9895 2 1285.70169 643.8568 Transcription initiation factor TFIID subunit 4 OS=Homo sapiens OX=9606 GN=TAF4 PE=1 SV=2 8.8 2097.9 - 366228 - - - 2.0814 - 2.839 0.374 - 594.5 1 2 0 0.0027 14 0 0 0 4.18E+06 2.09E+06 - - - 4.421 0.959 221125_WJC_METTL3_EV_vs_WT_F05.09896.09896.3 0.211 Aug-40 R.SYIQGGRPFTK.K "sp|O95785|WIZ_HUMAN,tr|A0A669KBG4|A0A669KBG4_HUMAN,tr|A0A2R8YFV2|A0A2R8YFV2_HUMAN,tr|A0A669KAV7|A0A669KAV7_HUMAN,tr|M0QXA7|M0QXA7_HUMAN,tr|A0A669KBH9|A0A669KBH9_HUMAN,tr|B9EGQ5|B9EGQ5_HUMAN" 7 1252.6564 1.2 62325 9896 3 1252.657707 418.5594 Protein Wiz OS=Homo sapiens OX=9606 GN=WIZ PE=1 SV=2 9.99 2098 - 358058 - - - 1.0266 - 1.623 0.113 - 62.1 2 2 0 0.0013 11 0 0 0 2.15E+07 1.79E+07 - - - 1.0359 1 221125_WJC_METTL3_EV_vs_WT_F05.09897.09897.2 2.17E-08 20-Oct L.ASNC[160.03]DEPMYVK.L sp|P25398|RS12_HUMAN 1 1312.5428 2.08 62326 9897 2 1312.544139 657.2787 40S ribosomal protein S12 OS=Homo sapiens OX=9606 GN=RPS12 PE=1 SV=3 4.37 2098.1 - 342764 - - - 1.0407 - 2.227 0.648 - 428.2 1 1 0 0.0014 11 0 0 0 2.51E+07 1.21E+07 - - - 5.9927 0.9994 221125_WJC_METTL3_EV_vs_WT_F05.09900.09900.2 3.50E-05 20-Sep R.VEIIANDQGNR[166.11].L "sp|P11021|BIP_HUMAN,sp|P48741|HSP77_HUMAN,sp|P54652|HSP72_HUMAN,sp|P0DMV8|HS71A_HUMAN,sp|P34931|HS71L_HUMAN,sp|P11142|HSP7C_HUMAN,sp|P0DMV9|HS71B_HUMAN,sp|P17066|HSP76_HUMAN,tr|E9PQQ4|E9PQQ4_HUMAN,tr|E9PNE6|E9PNE6_HUMAN,tr|E9PKE3|E9PKE3_HUMAN,tr|A0A7P0TB36|A0A7P0TB36_HUMAN,tr|E9PLF4|E9PLF4_HUMAN,tr|A0A7P0TAI0|A0A7P0TAI0_HUMAN,tr|Q53FA3|Q53FA3_HUMAN,tr|E9PI65|E9PI65_HUMAN,tr|E9PK54|E9PK54_HUMAN,tr|E9PN25|E9PN25_HUMAN,tr|E9PPY6|E9PPY6_HUMAN,tr|E9PQK7|E9PQK7_HUMAN,tr|A0A0G2JIW1|A0A0G2JIW1_HUMAN" 21 1237.629 0.17 62328 9900 2 1237.631641 619.8218 Endoplasmic reticulum chaperone BiP OS=Homo sapiens OX=9606 GN=HSPA5 PE=1 SV=2 4.37 2098.4 - 520141 - - - 2.1064 - 2.078 0.378 - 242.3 1 2 0 0.0026 11 0 0 0 3.11E+06 1.80E+07 - - - 3.8107 1 221125_WJC_METTL3_EV_vs_WT_F05.09903.09903.3 4.09E-10 15/64 R.AMIGHTDSAEAAPGTIR.G "sp|O00746|NDKM_HUMAN,tr|Q4TT34|Q4TT34_HUMAN,tr|A0A087WVT9|A0A087WVT9_HUMAN,tr|H0Y6J0|H0Y6J0_HUMAN,tr|F2Z2X0|F2Z2X0_HUMAN" 5 1696.8203 2.17 62331 9903 3 1696.822302 566.614 "Nucleoside diphosphate kinase, mitochondrial OS=Homo sapiens OX=9606 GN=NME4 PE=1 SV=1" 5.32 2098.6 - 1.25E+07 - - - 1.1981 - 2.931 0.588 - 230.3 1 2 0 0.002 17 0 0 0 2.72E+09 1.25E+09 - - - 7.8117 0.9639 221125_WJC_METTL3_EV_vs_WT_F05.09904.09904.3 3.82 13/32 R.LAELSDYR[166.11]R[166.11].L sp|Q96PK6|RBM14_HUMAN 1 1141.5995 0.001 62332 9904 3 1141.599562 381.5404 RNA-binding protein 14 OS=Homo sapiens OX=9606 GN=RBM14 PE=1 SV=2 6.07 2098.7 - 5.42E+06 - - - 0.0876 - 1.753 0.073 - 230.3 1 2 0 0.0001 9 0 0 0 0.00E+00 4.42E+07 - - - 1.0456 0.9996 221125_WJC_METTL3_EV_vs_WT_F05.09905.09905.2 1.80E-05 18-Oct K.DANNGNLQLR.N sp|P05455|LA_HUMAN 1 1113.5527 0.96 62333 9905 2 1113.553821 557.7836 Lupus La protein OS=Homo sapiens OX=9606 GN=SSB PE=1 SV=2 5.84 2098.7 - 2.55E+06 - - - 1.0211 - 1.852 0.398 - 448.9 1 2 0 0.0011 10 0 0 0 6.31E+07 6.56E+07 - - - 3.7005 0.9999 221125_WJC_METTL3_EV_vs_WT_F05.09907.09907.3 0.0185 Nov-36 R.GGDLMAYDRR.G "sp|P61978|HNRPK_HUMAN,tr|Q5T6W2|Q5T6W2_HUMAN" 2 1152.5346 1.31 62335 9907 3 1152.534638 385.1855 Heterogeneous nuclear ribonucleoprotein K OS=Homo sapiens OX=9606 GN=HNRNPK PE=1 SV=1 5.96 2098.9 - 1.65E+06 - - - 0.0408 - 2.201 0.373 - 226.4 1 2 0 0 10 0 0 0 3.40E+07 2.59E+07 - - - 5.0025 0.9911 221125_WJC_METTL3_EV_vs_WT_F05.09909.09909.3 0.0833 Nov-40 K.EVSHLNALEER[166.11].F "sp|P28340|DPOD1_HUMAN,tr|M0R3H8|M0R3H8_HUMAN,tr|M0R2B7|M0R2B7_HUMAN,tr|A0A087WYJ2|A0A087WYJ2_HUMAN" 4 1305.6552 1.22 62337 9909 3 1305.656267 436.2257 DNA polymerase delta catalytic subunit OS=Homo sapiens OX=9606 GN=POLD1 PE=1 SV=2 4.75 2099.1 - 491433 - - - 0.7797 - 1.675 0.168 - 227.2 1 2 0 0.001 11 0 0 0 1.20E+07 9.83E+06 - - - 1.8781 0.9999 221125_WJC_METTL3_EV_vs_WT_F05.09910.09910.2 0.0185 13/28 K.APGTNVAMASNQAVR[166.11].L sp|P49792|RBP2_HUMAN 1 1495.7441 0.28 62338 9910 2 1495.743899 748.8793 E3 SUMO-protein ligase RanBP2 OS=Homo sapiens OX=9606 GN=RANBP2 PE=1 SV=2 9.79 2099.3 - 473739 - - - -0.1217 - 2.72 0.498 - 387.9 1 2 0 -0.0002 15 0 0 0 3.24E+06 1.14E+07 - - - 5.1793 0.8599 221125_WJC_METTL3_EV_vs_WT_F05.09912.09912.3 0.421 Oct-40 R.SYIQGGR[166.11]PFTK[136.11].K "sp|O95785|WIZ_HUMAN,tr|A0A669KBG4|A0A669KBG4_HUMAN,tr|A0A2R8YFV2|A0A2R8YFV2_HUMAN,tr|A0A669KAV7|A0A669KAV7_HUMAN,tr|M0QXA7|M0QXA7_HUMAN,tr|A0A669KBH9|A0A669KBH9_HUMAN,tr|B9EGQ5|B9EGQ5_HUMAN" 7 1270.6789 1.2 62340 9912 3 1270.679742 424.5669 Protein Wiz OS=Homo sapiens OX=9606 GN=WIZ PE=1 SV=2 9.99 2099.5 - 327897 - - - 0.6697 - 1.298 0.086 - 105.6 1 2 0 0.0009 11 0 0 0 2.15E+07 1.79E+07 - - - 0.2395 1 221125_WJC_METTL3_EV_vs_WT_F05.09913.09913.2 7.52E-15 21/32 R.AMIGHTDSAEAAPGTIR.G "sp|O00746|NDKM_HUMAN,tr|Q4TT34|Q4TT34_HUMAN,tr|A0A087WVT9|A0A087WVT9_HUMAN,tr|H0Y6J0|H0Y6J0_HUMAN,tr|F2Z2X0|F2Z2X0_HUMAN" 5 1696.8203 2.12 62341 9913 2 1696.82322 849.4174 "Nucleoside diphosphate kinase, mitochondrial OS=Homo sapiens OX=9606 GN=NME4 PE=1 SV=1" 5.32 2099.6 - 313505 - - - 1.7391 - 3.795 0.685 - 1472.1 1 2 0 0.003 17 0 0 0 9.25E+07 4.37E+07 - - - 7.3784 0.9999 221125_WJC_METTL3_EV_vs_WT_F05.09914.09914.2 3.16E-06 14/26 K.ALSAVSAQAAAAQK[136.11].N "sp|O00268|TAF4_HUMAN,tr|V9GY14|V9GY14_HUMAN,tr|A0A0G2JRY5|A0A0G2JRY5_HUMAN" 3 1293.7132 2 62342 9914 2 1293.712758 647.8639 Transcription initiation factor TFIID subunit 4 OS=Homo sapiens OX=9606 GN=TAF4 PE=1 SV=2 8.8 2099.8 - 300790 - - - -0.3525 - 2.966 0.495 - 752.1 1 2 0 -0.0005 14 0 0 0 4.18E+06 2.09E+06 - - - 5.4252 1 221125_WJC_METTL3_EV_vs_WT_F05.09916.09916.2 6.95E-14 22/32 R.AMIGHTDSAEAAPGTIR[166.11].G "sp|O00746|NDKM_HUMAN,tr|Q4TT34|Q4TT34_HUMAN,tr|A0A087WVT9|A0A087WVT9_HUMAN,tr|H0Y6J0|H0Y6J0_HUMAN,tr|F2Z2X0|F2Z2X0_HUMAN" 5 1706.8285 2.12 62344 9916 2 1706.828793 854.4215 "Nucleoside diphosphate kinase, mitochondrial OS=Homo sapiens OX=9606 GN=NME4 PE=1 SV=1" 5.32 2100 - 161017 - - - 0.1488 - 3.767 0.75 - 1806.8 1 2 0 0.0003 17 0 0 0 9.26E+07 4.37E+07 - - - 7.8411 0.9999 221125_WJC_METTL3_EV_vs_WT_F05.09917.09917.2 3.28E-07 26-Oct R.QTPAGPETEEEPYR[166.11].R sp|Q13505|MTX1_HUMAN 1 1612.7245 1.48 62345 9917 2 1612.724637 807.3695 Metaxin-1 OS=Homo sapiens OX=9606 GN=MTX1 PE=1 SV=3 4.09 2100.2 - 128482 - - - 0.1153 - 2.061 0.631 - 371.3 1 2 0 0.0002 14 0 0 0 2.31E+06 1.56E+06 - - - 5.5163 0.9999 221125_WJC_METTL3_EV_vs_WT_F05.09923.09923.2 3.14E-06 13/22 R.TSLSAEDAEVTK.A sp|Q9P2D1|CHD7_HUMAN 1 1249.6038 1.46 62349 9923 2 1249.602065 625.8092 Chromodomain-helicase-DNA-binding protein 7 OS=Homo sapiens OX=9606 GN=CHD7 PE=1 SV=3 4.14 2101 - 3.29E+06 - - - -1.37 - 2.775 0.531 - 766.7 1 2 0 -0.0017 12 0 0 0 2.71E+07 1.86E+07 - - - 5.6479 0.9999 221125_WJC_METTL3_EV_vs_WT_F05.09925.09925.2 0.000444 22-Dec K.LGSTEVASNVPK.V "sp|Q9Y5A9|YTHD2_HUMAN,tr|S4R3V3|S4R3V3_HUMAN" 2 1200.635 1.49 62351 9925 2 1200.635844 601.3248 YTH domain-containing family protein 2 OS=Homo sapiens OX=9606 GN=YTHDF2 PE=1 SV=2 6 2101.1 - 2.14E+06 - - - 0.6888 - 2.505 0.46 - 480.6 1 2 0 0.0008 12 0 0 0 8.74E+07 5.86E+07 - - - 4.8545 0.9997 221125_WJC_METTL3_EV_vs_WT_F05.09926.09926.2 0.0134 20-Nov R.ISSVLAGGSC[160.03]R.A "sp|P02533|K1C14_HUMAN,sp|P08779|K1C16_HUMAN,tr|K7ENV3|K7ENV3_HUMAN" 3 1105.555 13.58 62352 9926 2 1105.555709 553.7848 "Keratin, type I cytoskeletal 14 OS=Homo sapiens OX=9606 GN=KRT14 PE=1 SV=4" 8.25 2101.2 - 2.07E+06 - - - 0.6476 - 1.87 0.386 - 173.2 1 2 0 0.0007 11 0 0 0 1.25E+08 9.21E+06 - - - 3.5851 0.9993 221125_WJC_METTL3_EV_vs_WT_F05.09928.09928.2 0.0894 14-Jul K.LQDEFENR.T "sp|P78344|IF4G2_HUMAN,tr|H0YEC5|H0YEC5_HUMAN,tr|H0Y3P2|H0Y3P2_HUMAN,tr|H0YCH5|H0YCH5_HUMAN,tr|H0YD77|H0YD77_HUMAN,tr|D3DQV9|D3DQV9_HUMAN" 6 1049.4778 0.51 62354 9928 2 1049.476915 525.7462 Eukaryotic translation initiation factor 4 gamma 2 OS=Homo sapiens OX=9606 GN=EIF4G2 PE=1 SV=1 4.14 2101.4 - 202204 - - - -0.8318 - 1.484 0.35 - 139.5 1 2 0 -0.0009 8 0 0 0 2.98E+06 5.81E+06 - - - 2.8163 0.9998 221125_WJC_METTL3_EV_vs_WT_F05.09931.09931.2 0.000312 18-Oct R.EQTEILESSR.M "sp|Q5T200|ZC3HD_HUMAN,tr|A0A7I2V4I5|A0A7I2V4I5_HUMAN" 2 1190.5779 0.64 62356 9931 2 1190.578005 596.2962 Zinc finger CCCH domain-containing protein 13 OS=Homo sapiens OX=9606 GN=ZC3H13 PE=1 SV=1 4.25 2101.8 - 390114 - - - 0.0916 - 1.867 0.453 - 572.2 1 2 0 0.0001 10 0 0 0 1.89E+07 2.97E+07 - - - 4.1295 0.9997 221125_WJC_METTL3_EV_vs_WT_F05.09935.09935.2 6.58E-05 22-Oct R.TSLSAEDAEVTK[136.11].A sp|Q9P2D1|CHD7_HUMAN 1 1257.618 1.46 62359 9935 2 1257.615175 629.8163 Chromodomain-helicase-DNA-binding protein 7 OS=Homo sapiens OX=9606 GN=CHD7 PE=1 SV=3 4.14 2102.1 - 1.62E+06 - - - -2.228 - 2.299 0.523 - 361.3 1 2 0 -0.0028 12 0 0 0 2.71E+07 1.86E+07 - - - 5.0934 0.9995 221125_WJC_METTL3_EV_vs_WT_F05.09939.09939.3 0.0309 Nov-36 K.LNYSDHDVIK.W "sp|Q96CW1|AP2M1_HUMAN,tr|A0A087WY71|A0A087WY71_HUMAN,tr|E9PFW3|E9PFW3_HUMAN" 3 1202.5932 1.03 62363 9939 3 1202.593156 401.8717 AP-2 complex subunit mu OS=Homo sapiens OX=9606 GN=AP2M1 PE=1 SV=2 5.21 2102.6 - 363514 - - - 0.0033 - 1.798 0.319 - 90.4 1 2 0 0 10 0 0 0 1.70E+07 1.64E+07 - - - 3.8099 0.9879 221125_WJC_METTL3_EV_vs_WT_F05.09944.09944.3 0.00108 13/48 Y.TIPAHQNLVTGVK.F sp|O43172|PRP4_HUMAN 1 1376.7776 3.03 62366 9944 3 1376.775337 459.9331 U4\U6 small nuclear ribonucleoprotein Prp4 OS=Homo sapiens OX=9606 GN=PRPF4 PE=1 SV=2 8.44 2103.3 - 953158 - - - -1.643 - 2.139 0.429 - 155.2 1 1 0 -0.0023 13 0 0 0 2.47E+07 8.15E+06 - - - 5.3838 0.9966 221125_WJC_METTL3_EV_vs_WT_F05.09946.09946.3 0.0296 Oct-36 K.LNYSDHDVIK[136.11].W "sp|Q96CW1|AP2M1_HUMAN,tr|A0A087WY71|A0A087WY71_HUMAN,tr|E9PFW3|E9PFW3_HUMAN" 3 1210.6074 1.03 62368 9946 3 1210.606142 404.5431 AP-2 complex subunit mu OS=Homo sapiens OX=9606 GN=AP2M1 PE=1 SV=2 5.21 2103.4 - 693956 - - - -0.9995 - 1.531 0.242 - 87.9 1 2 0 -0.0012 10 0 0 0 1.70E+07 1.64E+07 - - - 2.4816 0.9586 221125_WJC_METTL3_EV_vs_WT_F05.09947.09947.2 0.000271 18-Aug A.SNC[160.03]DEPMYVK.L sp|P25398|RS12_HUMAN 1 1241.5057 3.41 62369 9947 2 1241.501761 621.7601 40S ribosomal protein S12 OS=Homo sapiens OX=9606 GN=RPS12 PE=1 SV=3 4.37 2103.5 - 575344 - - - -3.1397 - 1.542 0.583 - 234.7 1 1 0 -0.0039 10 0 0 0 7.26E+06 2.13E+06 - - - 4.5547 0.9999 221125_WJC_METTL3_EV_vs_WT_F05.09951.09951.4 0.00419 Nov-96 R.AMIGHTDSAEAAPGTIR.G "sp|O00746|NDKM_HUMAN,tr|Q4TT34|Q4TT34_HUMAN,tr|A0A087WVT9|A0A087WVT9_HUMAN,tr|H0Y6J0|H0Y6J0_HUMAN,tr|F2Z2X0|F2Z2X0_HUMAN" 5 1696.8203 2.03 62371 9951 4 1696.820302 425.2123 "Nucleoside diphosphate kinase, mitochondrial OS=Homo sapiens OX=9606 GN=NME4 PE=1 SV=1" 5.32 2104 - 968277 - - - 0.0194 - 1.839 0.418 - 69.1 1 2 0 0 17 0 0 0 1.33E+07 6.55E+06 - - - 3.0758 0.9806 221125_WJC_METTL3_EV_vs_WT_F05.09960.09960.2 0.00495 22-Dec H.NETILASSGTDR[166.11].R "sp|Q09028|RBBP4_HUMAN,sp|Q16576|RBBP7_HUMAN,tr|H0YCT5|H0YCT5_HUMAN,tr|H0YDK2|H0YDK2_HUMAN,tr|Q5JP02|Q5JP02_HUMAN,tr|H0YEU5|H0YEU5_HUMAN,tr|Q5JP01|Q5JP01_HUMAN,tr|H0YF10|H0YF10_HUMAN,tr|E9PC52|E9PC52_HUMAN" 9 1272.6185 1.62 62378 9960 2 1272.618434 637.3165 Histone-binding protein RBBP4 OS=Homo sapiens OX=9606 GN=RBBP4 PE=1 SV=3 4.37 2105.1 - 336591 - - - -0.0746 - 2.1 0.334 - 640.2 1 1 0 -0.0001 12 0 0 0 1.83E+07 1.13E+07 - - - 3.4601 0.9941 221125_WJC_METTL3_EV_vs_WT_F05.09961.09961.3 1.29E-05 Nov-48 Y.TIPAHQNLVTGVK[136.11].F sp|O43172|PRP4_HUMAN 1 1384.7918 3.05 62379 9961 3 1384.790141 462.6045 U4\U6 small nuclear ribonucleoprotein Prp4 OS=Homo sapiens OX=9606 GN=PRPF4 PE=1 SV=2 8.44 2105.3 - 327352 - - - -1.1973 - 2.028 0.486 - 123.1 1 1 0 -0.0017 13 0 0 0 2.49E+07 8.15E+06 - - - 5.875 0.9916 221125_WJC_METTL3_EV_vs_WT_F05.09965.09965.2 0.00333 14-Jul R.DGYQQNFK[136.11].R "sp|Q14444|CAPR1_HUMAN,tr|G3V153|G3V153_HUMAN" 2 1006.46 1 62381 9965 2 1006.463191 504.2373 Caprin-1 OS=Homo sapiens OX=9606 GN=CAPRIN1 PE=1 SV=2 5.83 2105.8 - 340365 - - - 3.2103 - 1.219 0.317 - 127.4 1 2 0 0.0032 8 0 0 0 5.16E+06 5.18E+06 - - - 1.9786 0.9997 221125_WJC_METTL3_EV_vs_WT_F05.09966.09966.2 1.74E-05 24-Sep R.GLLQTEPQNNQAK.E sp|Q9Y3D6|FIS1_HUMAN 1 1439.7369 1.34 62382 9966 2 1439.735444 720.8757 Mitochondrial fission 1 protein OS=Homo sapiens OX=9606 GN=FIS1 PE=1 SV=2 6 2105.9 - 453988 - - - -0.9807 - 1.916 0.419 - 201.1 1 2 0 -0.0014 13 0 0 0 8.70E+07 6.49E+07 - - - 3.8041 0.9992 221125_WJC_METTL3_EV_vs_WT_F05.09968.09968.2 0.00987 24-Oct R.GLLQTEPQNNQAK[136.11].E sp|Q9Y3D6|FIS1_HUMAN 1 1447.7511 1.34 62384 9968 2 1447.747999 724.8828 Mitochondrial fission 1 protein OS=Homo sapiens OX=9606 GN=FIS1 PE=1 SV=2 6 2106.2 - 224915 - - - -2.1116 - 2.037 0.346 - 265.9 1 2 0 -0.0031 13 0 0 0 8.70E+07 6.49E+07 - - - 3.4216 0.9982 221125_WJC_METTL3_EV_vs_WT_F05.09969.09969.2 6.68E-05 18-Sep R.TADGIVSHLK[136.11].K sp|P30101|PDIA3_HUMAN 1 1047.5804 0.87 62385 9969 2 1047.576306 524.7975 Protein disulfide-isomerase A3 OS=Homo sapiens OX=9606 GN=PDIA3 PE=1 SV=4 6.41 2106.3 - 224324 - - - -3.9166 - 1.76 0.466 - 253.9 1 2 0 -0.0041 10 0 0 0 3.71E+06 4.26E+06 - - - 4.0596 0.9994 221125_WJC_METTL3_EV_vs_WT_F05.09973.09973.2 0.000309 20-Oct K.SFGSTC[160.03]QLSEK[136.11].F sp|P11388|TOP2A_HUMAN 1 1250.5693 0.91 62387 9973 2 1250.56629 626.2919 DNA topoisomerase 2-alpha OS=Homo sapiens OX=9606 GN=TOP2A PE=1 SV=3 5.72 2106.9 - 598024 - - - -2.3685 - 1.664 0.485 - 188.7 1 2 0 -0.003 11 0 0 0 7.06E+06 7.77E+06 - - - 3.9999 0.9997 221125_WJC_METTL3_EV_vs_WT_F05.09977.09977.2 0.252 18-Sep R.NFQEEQINTR[166.11].D "sp|Q8IXB1|DJC10_HUMAN,tr|A0A7P0Z431|A0A7P0Z431_HUMAN,tr|A0A7P0TB97|A0A7P0TB97_HUMAN,tr|A0A7P0TAQ9|A0A7P0TAQ9_HUMAN" 4 1287.6083 0.9 62391 9977 2 1287.607675 644.8114 DnaJ homolog subfamily C member 10 OS=Homo sapiens OX=9606 GN=DNAJC10 PE=1 SV=2 4.53 2107.4 - 532783 - - - -0.4846 - 2.15 0.311 - 341.8 1 2 0 -0.0006 10 0 0 0 1.29E+07 1.44E+07 - - - 3.4745 0.9995 221125_WJC_METTL3_EV_vs_WT_F05.09983.09983.2 8.12E-06 18-Sep R.NFQEEQINTR.D "sp|Q8IXB1|DJC10_HUMAN,tr|A0A7P0Z431|A0A7P0Z431_HUMAN,tr|A0A7P0TB97|A0A7P0TB97_HUMAN,tr|A0A7P0TAQ9|A0A7P0TAQ9_HUMAN" 4 1277.6 0.9 62395 9983 2 1277.596376 639.8073 DnaJ homolog subfamily C member 10 OS=Homo sapiens OX=9606 GN=DNAJC10 PE=1 SV=2 4.53 2108.1 - 656663 - - - -2.8593 - 2.165 0.485 - 379.9 1 2 0 -0.0037 10 0 0 0 1.29E+07 1.44E+07 - - - 4.7781 0.9526 221125_WJC_METTL3_EV_vs_WT_F05.09986.09986.2 0.263 16-Jul R.SYLLKINGK[136.11].V sp|P23921|RIR1_HUMAN 1 1042.6266 - 62398 9986 2 1042.626551 522.3206 Ribonucleoside-diphosphate reductase large subunit OS=Homo sapiens OX=9606 GN=RRM1 PE=1 SV=1 9.7 2108.5 - 363696 - - - -0.0767 - 1.374 0.166 - 177.2 1 2 1 -0.0001 9 0 0 0 - - - - - 1.1862 0.8651 221125_WJC_METTL3_EV_vs_WT_F05.09997.09997.3 0.39 Oct-36 K.IK[136.11]QEILPEER[166.11].M sp|O75534|CSDE1_HUMAN 1 1271.7204 0.32 62406 9997 3 1271.723416 424.9141 Cold shock domain-containing protein E1 OS=Homo sapiens OX=9606 GN=CSDE1 PE=1 SV=2 4.79 2109.8 - 1.59E+06 - - - 2.3543 - 1.702 0.137 - 170.3 1 2 1 0.003 10 0 0 0 6.89E+06 2.17E+07 - - - 1.6197 0.9994 221125_WJC_METTL3_EV_vs_WT_F05.09998.09998.3 0.000291 Nov-36 K.LFDYSK[136.11]PSAK[136.11].R "sp|Q05048|CSTF1_HUMAN,tr|A0A0A0MSZ9|A0A0A0MSZ9_HUMAN" 2 1170.6256 1.06 62407 9998 3 1170.626136 391.2158 Cleavage stimulation factor subunit 1 OS=Homo sapiens OX=9606 GN=CSTF1 PE=1 SV=1 8.5 2109.9 - 1.17E+06 - - - 0.4792 - 1.852 0.304 - 112.3 1 2 0 0.0006 10 0 0 0 1.49E+07 1.41E+07 - - - 3.7289 0.9859 221125_WJC_METTL3_EV_vs_WT_F05.10000.10000.3 0.0448 Nov-40 E.YDPTIEDSYRK.Q "sp|P01111|RASN_HUMAN,sp|P01112|RASH_HUMAN,sp|P62834|RAP1A_HUMAN,sp|P61224|RAP1B_HUMAN,sp|P01116|RASK_HUMAN,tr|F5H7Y6|F5H7Y6_HUMAN,tr|A0A804HKM6|A0A804HKM6_HUMAN,tr|F5H500|F5H500_HUMAN,tr|E7ESV4|E7ESV4_HUMAN,tr|F5H491|F5H491_HUMAN,tr|F5GX62|F5GX62_HUMAN,tr|F5H4H0|F5H4H0_HUMAN,tr|F5H6R7|F5H6R7_HUMAN,tr|A0A075B6Q0|A0A075B6Q0_HUMAN,tr|F5H077|F5H077_HUMAN,tr|F5H004|F5H004_HUMAN,tr|A0A804HJ06|A0A804HJ06_HUMAN,tr|F5H0B7|F5H0B7_HUMAN,tr|F5GYB5|F5GYB5_HUMAN,tr|F5GWU8|F5GWU8_HUMAN,tr|F5GYH7|F5GYH7_HUMAN" 21 1385.6463 1.03 62409 10000 3 1385.646026 462.8894 GTPase NRas OS=Homo sapiens OX=9606 GN=NRAS PE=1 SV=1 4.56 2110.1 - 552211 - - - -0.205 - 1.905 0.407 - 112.8 1 1 0 -0.0003 11 0 0 0 7.18E+06 6.98E+06 - - - 4.9084 0.9981 221125_WJC_METTL3_EV_vs_WT_F05.10001.10001.2 0.0398 16-Jul R.DQSGEVDFK[136.11].A "sp|P46020|KPB1_HUMAN,tr|A6NMN0|A6NMN0_HUMAN,tr|A6NIT2|A6NIT2_HUMAN" 3 1031.4651 2.19 62410 10001 2 1031.466226 516.7398 "Phosphorylase b kinase regulatory subunit alpha, skeletal muscle isoform OS=Homo sapiens OX=9606 GN=PHKA1 PE=1 SV=2" 4.03 2110.2 - 440747 - - - 1.0868 - 1.565 0.24 - 224.1 1 2 0 0.0011 9 0 0 0 1.42E+07 6.46E+06 - - - 2.109 1 221125_WJC_METTL3_EV_vs_WT_F05.10002.10002.3 8.58E-06 13/40 R.RMGESDDSILR.L "sp|P63220|RS21_HUMAN,tr|Q8WVC2|Q8WVC2_HUMAN" 2 1277.6034 0.46 62411 10002 3 1277.605333 426.8751 40S ribosomal protein S21 OS=Homo sapiens OX=9606 GN=RPS21 PE=1 SV=1 4.56 2110.4 - 279196 - - - 1.5138 - 2.658 0.5 - 374.3 1 2 0 0.0019 11 0 0 0 5.47E+06 1.18E+07 - - - 6.8911 0.9998 221125_WJC_METTL3_EV_vs_WT_F05.10003.10003.2 4.36E-05 20-Aug R.R[166.11]MGESDDSILR[166.11].L "sp|P63220|RS21_HUMAN,tr|Q8WVC2|Q8WVC2_HUMAN" 2 1297.6199 2.5 62412 10003 2 1297.620234 649.8172 40S ribosomal protein S21 OS=Homo sapiens OX=9606 GN=RPS21 PE=1 SV=1 4.56 2110.5 - 225313 - - - 0.2273 - 1.894 0.432 - 106.9 1 2 0 0.0003 11 0 0 0 1.24E+07 4.96E+06 - - - 3.9595 0.9994 221125_WJC_METTL3_EV_vs_WT_F05.10004.10004.2 5.71E-05 24-Oct R.QVTGQPQNASFVK.R "sp|Q5JTV8|TOIP1_HUMAN,tr|J3KN66|J3KN66_HUMAN,tr|A0A0A0MSK5|A0A0A0MSK5_HUMAN" 3 1402.7205 2.42 62413 10004 2 1402.724092 702.3675 Torsin-1A-interacting protein 1 OS=Homo sapiens OX=9606 GN=TOR1AIP1 PE=1 SV=2 8.75 2110.6 - 137140 - - - 2.5764 - 1.748 0.506 - 247.9 1 2 0 0.0036 13 0 0 0 4.59E+06 1.90E+06 - - - 4.2105 0.9993 221125_WJC_METTL3_EV_vs_WT_F05.10007.10007.3 0.000173 Dec-40 K.MKETAEAYLGK.K "sp|P11021|BIP_HUMAN,tr|A0A7P0TB36|A0A7P0TB36_HUMAN,tr|A0A7P0TAI0|A0A7P0TAI0_HUMAN" 3 1239.6169 0.49 62414 10007 3 1239.618971 414.2129 Endoplasmic reticulum chaperone BiP OS=Homo sapiens OX=9606 GN=HSPA5 PE=1 SV=2 5.9 2111 - 1.96E+06 - - - 1.6513 - 2.044 0.418 - 220.5 1 2 1 0.002 11 0 0 0 4.28E+07 8.67E+07 - - - 5.2307 1 221125_WJC_METTL3_EV_vs_WT_F05.10009.10009.3 9.86E-07 Dec-40 K.GDYYEAHQMYR[166.11].T sp|Q7L5D6|GET4_HUMAN 1 1441.596 1.5 62416 10009 3 1441.5981 481.5393 Golgi to ER traffic protein 4 homolog OS=Homo sapiens OX=9606 GN=GET4 PE=1 SV=1 5.32 2111.3 - 542776 - - - 1.4435 - 2.304 0.575 - 183.8 1 2 0 0.0021 11 0 0 0 5.81E+06 3.86E+06 - - - 7.3212 0.9925 221125_WJC_METTL3_EV_vs_WT_F05.10010.10010.3 0.00715 Aug-32 R.MDYEDDRLR.D "sp|P43243|MATR3_HUMAN,tr|A8MXP9|A8MXP9_HUMAN,tr|D6R991|D6R991_HUMAN,tr|A0A0R4J2E8|A0A0R4J2E8_HUMAN,tr|D6REM6|D6REM6_HUMAN" 5 1211.5241 1.47 62417 10010 3 1211.526351 404.8486 Matrin-3 OS=Homo sapiens OX=9606 GN=MATR3 PE=1 SV=2 4.23 2111.4 - 471729 - - - 1.8695 - 1.505 0.323 - 105.9 1 2 1 0.0023 9 0 0 0 1.19E+07 8.06E+06 - - - 3.3725 0.9997 221125_WJC_METTL3_EV_vs_WT_F05.10011.10011.2 0.00499 14/18 K.R[166.11]VDALNDEIR[166.11].Q sp|Q9UQE7|SMC3_HUMAN 1 1219.6424 6.56 62418 10011 2 1219.644169 610.8285 Structural maintenance of chromosomes protein 3 OS=Homo sapiens OX=9606 GN=SMC3 PE=1 SV=2 4.56 2111.5 - 392692 - - - 1.4594 - 2.378 0.392 - 580.1 1 2 0 0.0018 10 0 0 0 4.39E+07 6.69E+06 - - - 4.3537 0.9614 221125_WJC_METTL3_EV_vs_WT_F05.10012.10012.3 0.0137 Nov-44 M.QIQHPTASLIAK[136.11].V "sp|Q92526|TCPW_HUMAN,sp|P40227|TCPZ_HUMAN" 2 1313.7547 0.49 62419 10012 3 1313.756776 438.9255 T-complex protein 1 subunit zeta-2 OS=Homo sapiens OX=9606 GN=CCT6B PE=1 SV=5 8.76 2111.6 - 367812 - - - 1.5916 - 2.036 0.346 - 193.2 1 1 0 0.0021 12 0 0 0 3.57E+06 7.21E+06 - - - 4.3677 0.9996 221125_WJC_METTL3_EV_vs_WT_F05.10013.10013.2 9.82E-05 18-Oct R.TIVEEVQDGK.V "sp|Q04695|K1C17_HUMAN,tr|F5GWP8|F5GWP8_HUMAN" 2 1116.5663 18.56 62420 10013 2 1116.568259 559.2904 "Keratin, type I cytoskeletal 17 OS=Homo sapiens OX=9606 GN=KRT17 PE=1 SV=2" 4.14 2111.8 - 365305 - - - 1.7822 - 1.646 0.497 - 262.5 1 2 0 0.002 10 0 0 0 4.47E+06 2.41E+05 - - - 4.1023 0.9998 221125_WJC_METTL3_EV_vs_WT_F05.10014.10014.2 0.00015 18-Oct R.TADGIVSHLK.K sp|P30101|PDIA3_HUMAN 1 1039.5662 0.87 62421 10014 2 1039.567321 520.7904 Protein disulfide-isomerase A3 OS=Homo sapiens OX=9606 GN=PDIA3 PE=1 SV=4 6.41 2111.9 - 303430 - - - 1.0697 - 1.781 0.499 - 292.2 1 2 0 0.0011 10 0 0 0 3.71E+06 4.26E+06 - - - 4.3373 1 221125_WJC_METTL3_EV_vs_WT_F05.10021.10021.2 3.25E-05 15/30 R.GGGPAGAGGEAPAALR.G sp|Q5RKV6|EXOS6_HUMAN 1 1307.6582 1.31 62427 10021 2 1307.66132 654.8364 Exosome complex component MTR3 OS=Homo sapiens OX=9606 GN=EXOSC6 PE=1 SV=1 6 2112.8 - 682801 - - - 2.3768 - 3.02 0.583 - 600.5 1 2 0 0.0031 16 0 0 0 2.25E+07 1.72E+07 - - - 6.0634 0.9996 221125_WJC_METTL3_EV_vs_WT_F05.10023.10023.2 5.71E-07 16-Oct K.DVDAAYMNK.V "sp|P48668|K2C6C_HUMAN,sp|P04259|K2C6B_HUMAN,sp|P13647|K2C5_HUMAN,sp|Q14CN4|K2C72_HUMAN,sp|O95678|K2C75_HUMAN,sp|P02538|K2C6A_HUMAN,tr|F8W0C6|F8W0C6_HUMAN,tr|H0YIN9|H0YIN9_HUMAN" 8 1025.4488 0.94 62428 10023 2 1025.451333 513.7317 "Keratin, type II cytoskeletal 6C OS=Homo sapiens OX=9606 GN=KRT6C PE=1 SV=3" 4.21 2113 - 1.45E+06 - - - 2.474 - 2.16 0.466 - 261 1 2 0 0.0025 9 0 0 0 1.03E+07 1.10E+07 - - - 4.71 0.9998 221125_WJC_METTL3_EV_vs_WT_F05.10026.10026.2 1.09E-06 24-Dec K.EVSTNTAMIQTSK.T "sp|P13646|K1C13_HUMAN,tr|K7ERE3|K7ERE3_HUMAN" 2 1408.6868 999 62431 10026 2 1408.689639 705.3507 "Keratin, type I cytoskeletal 13 OS=Homo sapiens OX=9606 GN=KRT13 PE=1 SV=4" 6.1 2113.2 - 732311 - - - 2.0189 - 2.261 0.576 - 398.8 1 2 0 0.0028 13 0 0 0 4.60E+06 0.00E+00 - - - 5.3882 0.9996 221125_WJC_METTL3_EV_vs_WT_F05.10027.10027.3 0.0395 Sep-48 K.EAAYHPEVAPDVR[166.11].L sp|Q9Y490|TLN1_HUMAN 1 1462.708 0.84 62432 10027 3 1462.707309 488.5766 Talin-1 OS=Homo sapiens OX=9606 GN=TLN1 PE=1 SV=3 4.65 2113.4 - 731980 - - - -0.4813 - 1.872 0.345 - 94.2 1 2 0 -0.0007 13 0 0 0 4.40E+06 5.25E+06 - - - 4.0862 1 221125_WJC_METTL3_EV_vs_WT_F05.10028.10028.2 4.33E-09 17/30 R.GGGPAGAGGEAPAALR[166.11].G sp|Q5RKV6|EXOS6_HUMAN 1 1317.6665 1.34 62433 10028 2 1317.673956 659.8405 Exosome complex component MTR3 OS=Homo sapiens OX=9606 GN=EXOSC6 PE=1 SV=1 6 2113.5 - 687454 - - - 5.6721 - 3.124 0.602 - 859.7 1 2 0 0.0075 16 0 0 0 2.23E+07 1.66E+07 - - - 6.2856 0.9998 221125_WJC_METTL3_EV_vs_WT_F05.10034.10034.2 0.000681 24-Dec R.YIASVQGSTPSPR[166.11].Q "sp|P49792|RBP2_HUMAN,tr|F8WBP7|F8WBP7_HUMAN" 2 1371.7022 0.31 62439 10034 2 1371.700645 686.8584 E3 SUMO-protein ligase RanBP2 OS=Homo sapiens OX=9606 GN=RANBP2 PE=1 SV=2 8.75 2114.3 - 288642 - - - -1.1329 - 2.2 0.451 - 405.2 1 2 0 -0.0016 13 0 0 0 8.21E+05 2.68E+06 - - - 4.3952 0.9942 221125_WJC_METTL3_EV_vs_WT_F05.10035.10035.2 0.00233 18-Oct K.IK[136.11]QEILPEER[166.11].M sp|O75534|CSDE1_HUMAN 1 1271.7204 0.38 62440 10035 2 1271.723416 636.8675 Cold shock domain-containing protein E1 OS=Homo sapiens OX=9606 GN=CSDE1 PE=1 SV=2 4.79 2114.4 - 270202 - - - 2.3543 - 2.158 0.414 - 295.6 1 2 1 0.003 10 0 0 0 7.21E+05 1.90E+06 - - - 4.2449 0.9998 221125_WJC_METTL3_EV_vs_WT_F05.10039.10039.2 9.69E-06 22-Sep K.ETVEEQVSTTER[166.11].V "sp|Q13619|CUL4A_HUMAN,tr|A0A0A0MR50|A0A0A0MR50_HUMAN" 2 1416.6608 0.65 62444 10039 2 1416.662637 709.3377 Cullin-4A OS=Homo sapiens OX=9606 GN=CUL4A PE=1 SV=3 4.09 2114.9 - 80785.5 - - - 1.3052 - 1.865 0.506 - 356.4 1 2 0 0.0018 12 0 0 0 4.06E+05 6.25E+05 - - - 4.4176 0.9999 221125_WJC_METTL3_EV_vs_WT_F05.10043.10043.2 5.75E-07 22-Nov R.EAGDVC[160.03]YADVQK.D "sp|Q13242|SRSF9_HUMAN,tr|H0YIB4|H0YIB4_HUMAN" 2 1353.5871 1.51 62447 10043 2 1353.587602 677.8008 Serine\arginine-rich splicing factor 9 OS=Homo sapiens OX=9606 GN=SRSF9 PE=1 SV=1 4.03 2115.3 - 1.92E+06 - - - 0.3849 - 1.951 0.59 - 366.3 1 2 0 0.0005 12 0 0 0 3.09E+07 2.05E+07 - - - 5.1571 0.9974 221125_WJC_METTL3_EV_vs_WT_F05.10044.10044.3 0.00402 Oct-36 K.IKQEILPEER.M sp|O75534|CSDE1_HUMAN 1 1253.698 0.32 62448 10044 3 1253.700023 418.9066 Cold shock domain-containing protein E1 OS=Homo sapiens OX=9606 GN=CSDE1 PE=1 SV=2 4.79 2115.4 - 1.81E+06 - - - 1.6519 - 1.933 0.323 - 204.5 1 2 1 0.0021 10 0 0 0 6.82E+06 2.16E+07 - - - 4.0653 0.9859 221125_WJC_METTL3_EV_vs_WT_F05.10045.10045.3 0.0083 Nov-36 R.IR[166.11]ELTAVVQK[136.11].R "sp|P23396|RS3_HUMAN,tr|E9PL09|E9PL09_HUMAN,tr|E9PK82|E9PK82_HUMAN,tr|F2Z2S8|F2Z2S8_HUMAN,tr|H0YCJ7|H0YCJ7_HUMAN,tr|E9PQ96|E9PQ96_HUMAN,tr|E9PJH4|E9PJH4_HUMAN,tr|E9PPU1|E9PPU1_HUMAN,tr|H0YF32|H0YF32_HUMAN" 9 1173.72 0.68 62449 10045 3 1173.720946 392.2473 40S ribosomal protein S3 OS=Homo sapiens OX=9606 GN=RPS3 PE=1 SV=2 8.75 2115.4 - 1.39E+06 - - - 0.7821 - 1.795 0.206 - 159.8 1 2 1 0.0009 10 0 0 0 1.15E+08 1.68E+08 - - - 2.5449 1 221125_WJC_METTL3_EV_vs_WT_F05.10046.10046.3 7.25E-05 13/40 K.QVSSHIQVLAR[166.11].R "sp|Q15562|TEAD2_HUMAN,sp|P28347|TEAD1_HUMAN,sp|Q15561|TEAD4_HUMAN,sp|Q99594|TEAD3_HUMAN,tr|A0A1X7SBS4|A0A1X7SBS4_HUMAN,tr|Q53GI4|Q53GI4_HUMAN,tr|H0YE88|H0YE88_HUMAN,tr|H0YG62|H0YG62_HUMAN,tr|H0YGS2|H0YGS2_HUMAN,tr|H0YEJ9|H0YEJ9_HUMAN,tr|A0A0A0MRF3|A0A0A0MRF3_HUMAN,tr|A0A7P0SNI2|A0A7P0SNI2_HUMAN" 12 1246.7021 1.67 62450 10046 3 1246.703513 416.5747 Transcriptional enhancer factor TEF-4 OS=Homo sapiens OX=9606 GN=TEAD2 PE=1 SV=2 9.76 2115.5 - 1.16E+06 - - - 1.1021 - 2.287 0.482 - 326 1 2 0 0.0014 11 0 0 0 1.92E+07 1.15E+07 - - - 6.2635 0.9971 221125_WJC_METTL3_EV_vs_WT_F05.10047.10047.3 0.00743 Sep-44 R.LLSQVVR[166.11]PQESR[166.11].S "sp|Q5T200|ZC3HD_HUMAN,tr|A0A7I2V4I5|A0A7I2V4I5_HUMAN" 2 1430.8109 1.55 62451 10047 3 1430.812874 477.9442 Zinc finger CCCH domain-containing protein 13 OS=Homo sapiens OX=9606 GN=ZC3H13 PE=1 SV=1 9.6 2115.6 - 919662 - - - 1.4132 - 1.758 0.241 - 106.2 1 2 0 0.002 12 0 0 0 1.29E+07 8.29E+06 - - - 2.7902 0.9845 221125_WJC_METTL3_EV_vs_WT_F05.10050.10050.3 0.51 Sep-32 R.HMYHSLYLK[136.11].V "sp|P84098|RL19_HUMAN,tr|J3KTE4|J3KTE4_HUMAN,tr|A0A7I2YQG2|A0A7I2YQG2_HUMAN,tr|J3QR09|J3QR09_HUMAN" 4 1198.6048 1.05 62454 10050 3 1198.607519 400.5422 60S ribosomal protein L19 OS=Homo sapiens OX=9606 GN=RPL19 PE=1 SV=1 8.51 2115.9 - 645561 - - - 2.2268 - 1.575 0.19 - 121.4 1 2 0 0.0027 9 0 0 0 5.22E+06 4.96E+06 - - - 2.0266 0.9976 221125_WJC_METTL3_EV_vs_WT_F05.10051.10051.2 0.174 16-Oct R.RLVGDVIQR.F "sp|O00746|NDKM_HUMAN,tr|Q4TT34|Q4TT34_HUMAN,tr|A0A087WVT9|A0A087WVT9_HUMAN,tr|H0Y6J0|H0Y6J0_HUMAN,tr|F2Z2X0|F2Z2X0_HUMAN" 5 1054.6247 2.01 62455 10051 2 1054.626914 528.3196 "Nucleoside diphosphate kinase, mitochondrial OS=Homo sapiens OX=9606 GN=NME4 PE=1 SV=1" 9.6 2116 - 637312 - - - 2.0737 - 1.976 0.185 - 195.4 1 2 0 0.0022 9 0 0 0 3.20E+07 1.59E+07 - - - 2.3771 0.9984 221125_WJC_METTL3_EV_vs_WT_F05.10054.10054.2 0.276 16-Oct R.R[166.11]LVGDVIQR[166.11].F "sp|O00746|NDKM_HUMAN,tr|Q4TT34|Q4TT34_HUMAN,tr|A0A087WVT9|A0A087WVT9_HUMAN,tr|H0Y6J0|H0Y6J0_HUMAN,tr|F2Z2X0|F2Z2X0_HUMAN" 5 1074.6413 2.01 62458 10054 2 1074.64185 538.3279 "Nucleoside diphosphate kinase, mitochondrial OS=Homo sapiens OX=9606 GN=NME4 PE=1 SV=1" 9.6 2116.4 - 416426 - - - 0.5425 - 1.914 0.155 - 194.8 1 2 0 0.0006 9 0 0 0 3.20E+07 1.59E+07 - - - 2.0638 0.9998 221125_WJC_METTL3_EV_vs_WT_F05.10060.10060.2 4.83E-05 26-Sep R.LDAEPRPPPTQEAA.- "sp|Q9Y285|SYFA_HUMAN,tr|K7ER00|K7ER00_HUMAN" 2 1490.7365 8.71 62464 10060 2 1490.736039 746.3755 Phenylalanine--tRNA ligase alpha subunit OS=Homo sapiens OX=9606 GN=FARSA PE=1 SV=3 4.14 2117.1 - 215620 - - - -0.324 - 1.956 0.489 - 248.7 1 2 0 -0.0005 14 0 0 0 3.89E+06 4.47E+05 - - - 4.3362 0.9998 221125_WJC_METTL3_EV_vs_WT_F05.10064.10064.2 5.42E-05 22-Oct R.EAGDVC[160.03]YADVQK[136.11].D "sp|Q13242|SRSF9_HUMAN,tr|H0YIB4|H0YIB4_HUMAN" 2 1361.6013 1.51 62467 10064 2 1361.601658 681.8079 Serine\arginine-rich splicing factor 9 OS=Homo sapiens OX=9606 GN=SRSF9 PE=1 SV=1 4.03 2117.6 - 2.49E+06 - - - 0.2769 - 1.811 0.51 - 284.1 1 2 0 0.0004 12 0 0 0 3.09E+07 2.04E+07 - - - 4.3703 0.9989 221125_WJC_METTL3_EV_vs_WT_F05.10065.10065.3 0.0252 15/36 R.IRELTAVVQK.R "sp|P23396|RS3_HUMAN,tr|E9PL09|E9PL09_HUMAN,tr|E9PK82|E9PK82_HUMAN,tr|F2Z2S8|F2Z2S8_HUMAN,tr|H0YCJ7|H0YCJ7_HUMAN,tr|E9PQ96|E9PQ96_HUMAN,tr|E9PJH4|E9PJH4_HUMAN,tr|E9PPU1|E9PPU1_HUMAN,tr|H0YF32|H0YF32_HUMAN" 9 1155.6976 0.68 62468 10065 3 1155.69726 386.2398 40S ribosomal protein S3 OS=Homo sapiens OX=9606 GN=RPS3 PE=1 SV=2 8.75 2117.6 - 2.28E+06 - - - -0.2579 - 2.676 0.272 - 377.2 1 2 1 -0.0003 10 0 0 0 1.15E+08 1.68E+08 - - - 4.4471 0.9997 221125_WJC_METTL3_EV_vs_WT_F05.10066.10066.2 0.000332 13/18 R.RQLDSIVGER.G "sp|P48668|K2C6C_HUMAN,sp|P13647|K2C5_HUMAN,sp|P02538|K2C6A_HUMAN,tr|F8W0C6|F8W0C6_HUMAN" 4 1171.6309 999 62469 10066 2 1171.631642 586.8227 "Keratin, type II cytoskeletal 6C OS=Homo sapiens OX=9606 GN=KRT6C PE=1 SV=3" 6.07 2117.7 - 1.74E+06 - - - 0.6034 - 2.271 0.338 - 284.8 1 2 0 0.0007 10 0 0 0 1.11E+08 0.00E+00 - - - 3.8267 0.9986 221125_WJC_METTL3_EV_vs_WT_F05.10070.10070.3 1.55E-05 Dec-40 K.ELAENNHILER.F "sp|Q9UHD2|TBK1_HUMAN,tr|A0A7I2V646|A0A7I2V646_HUMAN,tr|A0A494C045|A0A494C045_HUMAN,tr|A0A7I2V4W4|A0A7I2V4W4_HUMAN,tr|A0A7I2V3B7|A0A7I2V3B7_HUMAN,tr|A0A494C0X2|A0A494C0X2_HUMAN,tr|A0A494C167|A0A494C167_HUMAN,tr|A0A7I2V3Y6|A0A7I2V3Y6_HUMAN,tr|A0A7I2V2F4|A0A7I2V2F4_HUMAN,tr|A0A7I2V643|A0A7I2V643_HUMAN" 10 1336.6735 77.25 62473 10070 3 1336.681276 446.5651 Serine\threonine-protein kinase TBK1 OS=Homo sapiens OX=9606 GN=TBK1 PE=1 SV=1 4.75 2118.1 - 877358 - - - 5.7965 - 2.513 0.428 - 271.9 1 2 0 0.0077 11 0 0 0 7.13E+06 9.23E+04 - - - 5.9274 1 221125_WJC_METTL3_EV_vs_WT_F05.10073.10073.2 4.43E-08 22-Nov R.ETYGEMADC[160.03]C[160.03]AK.Q "sp|P02768|ALBU_HUMAN,tr|A0A087WWT3|A0A087WWT3_HUMAN,tr|H7C013|H7C013_HUMAN,tr|A0A0C4DGB6|A0A0C4DGB6_HUMAN" 4 1433.5261 999 62476 10073 2 1433.526772 717.7703 Albumin OS=Homo sapiens OX=9606 GN=ALB PE=1 SV=2 4.14 2118.4 - 365669 - - - 0.443 - 1.985 0.739 - 361.4 1 2 0 0.0006 12 0 0 0 8.56E+06 0.00E+00 - - - 6.303 0.9999 221125_WJC_METTL3_EV_vs_WT_F05.10074.10074.2 8.89E-06 20-Nov K.GSQFGQSC[160.03]C[160.03]LR.A "sp|P07814|SYEP_HUMAN,tr|V9GYZ6|V9GYZ6_HUMAN" 2 1298.5496 0.98 62477 10074 2 1298.548898 650.2821 Bifunctional glutamate\proline--tRNA ligase OS=Homo sapiens OX=9606 GN=EPRS1 PE=1 SV=5 8.07 2118.6 - 312521 - - - -0.5329 - 1.932 0.531 - 405.2 1 2 0 -0.0007 11 0 0 0 1.64E+07 1.68E+07 - - - 4.7443 0.9998 221125_WJC_METTL3_EV_vs_WT_F05.10075.10075.2 1.31E-06 26-Oct R.FLTNGPSSSPGQER[166.11].E "sp|Q7Z406|MYH14_HUMAN,tr|M0QY43|M0QY43_HUMAN" 2 1485.7087 1.01 62478 10075 2 1485.705588 743.8616 Myosin-14 OS=Homo sapiens OX=9606 GN=MYH14 PE=1 SV=2 6 2118.7 - 230877 - - - -2.1222 - 2.217 0.634 - 332.6 1 2 0 -0.0032 14 0 0 0 3.44E+06 3.40E+06 - - - 5.7206 0.9983 221125_WJC_METTL3_EV_vs_WT_F05.10076.10076.2 0.00768 20-Aug R.VEIIANDQGNR.L "sp|P11021|BIP_HUMAN,sp|P48741|HSP77_HUMAN,sp|P54652|HSP72_HUMAN,sp|P0DMV8|HS71A_HUMAN,sp|P34931|HS71L_HUMAN,sp|P11142|HSP7C_HUMAN,sp|P0DMV9|HS71B_HUMAN,sp|P17066|HSP76_HUMAN,tr|E9PQQ4|E9PQQ4_HUMAN,tr|E9PNE6|E9PNE6_HUMAN,tr|E9PKE3|E9PKE3_HUMAN,tr|A0A7P0TB36|A0A7P0TB36_HUMAN,tr|E9PLF4|E9PLF4_HUMAN,tr|A0A7P0TAI0|A0A7P0TAI0_HUMAN,tr|Q53FA3|Q53FA3_HUMAN,tr|E9PI65|E9PI65_HUMAN,tr|E9PK54|E9PK54_HUMAN,tr|E9PN25|E9PN25_HUMAN,tr|E9PPY6|E9PPY6_HUMAN,tr|E9PQK7|E9PQK7_HUMAN,tr|A0A0G2JIW1|A0A0G2JIW1_HUMAN" 21 1227.6208 0.24 62479 10076 2 1227.621661 614.8177 Endoplasmic reticulum chaperone BiP OS=Homo sapiens OX=9606 GN=HSPA5 PE=1 SV=2 4.37 2118.8 - 223577 - - - 0.7307 - 1.359 0.294 - 146 1 2 0 0.0009 11 0 0 0 1.20E+06 4.95E+06 - - - 2.042 0.9957 221125_WJC_METTL3_EV_vs_WT_F05.10081.10081.3 0.406 Oct-44 R.LLSQVVRPQESR.S "sp|Q5T200|ZC3HD_HUMAN,tr|A0A7I2V4I5|A0A7I2V4I5_HUMAN" 2 1410.7943 2.1 62483 10081 3 1410.794728 471.272 Zinc finger CCCH domain-containing protein 13 OS=Homo sapiens OX=9606 GN=ZC3H13 PE=1 SV=1 9.6 2119.4 - 854105 - - - 0.2949 - 1.671 0.212 - 140.8 1 2 0 0.0004 12 0 0 0 2.79E+06 1.33E+06 - - - 2.3266 0.9962 221125_WJC_METTL3_EV_vs_WT_F05.10082.10082.2 0.195 22-Jun R.SPPPGMGLNQNR.G sp|P23246|SFPQ_HUMAN 1 1266.6139 1.3 62484 10082 2 1266.613653 634.3142 "Splicing factor, proline- and glutamine-rich OS=Homo sapiens OX=9606 GN=SFPQ PE=1 SV=2" 9.47 2119.6 - 115276 - - - -0.1982 - 1.202 0.239 - 112.3 1 2 0 -0.0003 12 0 0 0 1.42E+06 1.09E+06 - - - 1.2903 0.9612 221125_WJC_METTL3_EV_vs_WT_F05.10083.10083.2 0.0275 12-Jul K.IRDWYQR.Q "sp|Q04695|K1C17_HUMAN,sp|P02533|K1C14_HUMAN,sp|P08779|K1C16_HUMAN,tr|K7EPJ9|K7EPJ9_HUMAN,tr|F5GWP8|F5GWP8_HUMAN" 5 1035.525 307.49 62485 10083 2 1035.526447 518.7698 "Keratin, type I cytoskeletal 17 OS=Homo sapiens OX=9606 GN=KRT17 PE=1 SV=2" 8.75 2119.6 - 2.91E+06 - - - 1.3848 - 1.623 0.153 - 135.9 1 2 1 0.0014 7 0 0 0 3.66E+08 1.19E+06 - - - 1.7051 0.959 221125_WJC_METTL3_EV_vs_WT_F05.10084.10084.2 1.37 18-Oct R.IRELTAVVQK.R "sp|P23396|RS3_HUMAN,tr|E9PL09|E9PL09_HUMAN,tr|E9PK82|E9PK82_HUMAN,tr|F2Z2S8|F2Z2S8_HUMAN,tr|H0YCJ7|H0YCJ7_HUMAN,tr|E9PQ96|E9PQ96_HUMAN,tr|E9PJH4|E9PJH4_HUMAN,tr|E9PPU1|E9PPU1_HUMAN,tr|H0YF32|H0YF32_HUMAN" 9 1155.6976 0.71 62486 10084 2 1155.698535 578.8561 40S ribosomal protein S3 OS=Homo sapiens OX=9606 GN=RPS3 PE=1 SV=2 8.75 2119.7 - 1.85E+06 - - - 0.8454 - 1.704 0.126 - 380.3 1 2 1 0.001 10 0 0 0 3.68E+07 5.17E+07 - - - 1.459 0.9884 221125_WJC_METTL3_EV_vs_WT_F05.10085.10085.2 0.0199 16-Nov Y.PDGIISK[136.11]PK[136.11].N sp|Q86U44|MTA70_HUMAN 1 969.583 0.001 62487 10085 2 969.582315 485.7988 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 9.01 2119.8 - 1.47E+06 - - - -0.6879 - 2.258 0.381 - 343.9 1 1 0 -0.0007 9 0 0 0 0.00E+00 1.16E+07 - - - 4.2112 0.9999 221125_WJC_METTL3_EV_vs_WT_F05.10086.10086.2 8.73E-07 14/22 K.TTGEVVSGVVSK.V "sp|Q14008|CKAP5_HUMAN,tr|E9PQH5|E9PQH5_HUMAN" 2 1161.6241 1.01 62488 10086 2 1161.625639 581.8193 Cytoskeleton-associated protein 5 OS=Homo sapiens OX=9606 GN=CKAP5 PE=1 SV=3 5.66 2119.9 - 1.01E+06 - - - 1.3094 - 2.33 0.548 - 585.1 1 2 0 0.0015 12 0 0 0 6.43E+06 6.38E+06 - - - 5.3137 1 221125_WJC_METTL3_EV_vs_WT_F05.10088.10088.2 1.00E-06 14/26 K.GDATVSYEDPPTAK[136.11].A "sp|Q01844|EWS_HUMAN,tr|B0QYK0|B0QYK0_HUMAN,tr|H7BY36|H7BY36_HUMAN,tr|A0A0D9SFL3|A0A0D9SFL3_HUMAN,tr|C9JGE3|C9JGE3_HUMAN" 5 1457.6766 0.68 62490 10088 2 1457.67595 729.8456 RNA-binding protein EWS OS=Homo sapiens OX=9606 GN=EWSR1 PE=1 SV=1 4.03 2120.2 - 588043 - - - -0.4144 - 2.715 0.655 - 353.1 1 2 0 -0.0006 14 0 0 0 6.45E+06 9.54E+06 - - - 6.3851 1 221125_WJC_METTL3_EV_vs_WT_F05.10089.10089.3 5.10E-07 14/44 R.AR[166.11]PAEVGGMQLR[166.11].F "sp|P33316|DUT_HUMAN,tr|H0YNJ9|H0YNJ9_HUMAN,tr|H0YMM5|H0YMM5_HUMAN,tr|H0YKC5|H0YKC5_HUMAN,tr|H0YKI0|H0YKI0_HUMAN,tr|H0YNW5|H0YNW5_HUMAN" 6 1303.6934 0.65 62491 10089 3 1303.696408 435.5717 "Deoxyuridine 5'-triphosphate nucleotidohydrolase, mitochondrial OS=Homo sapiens OX=9606 GN=DUT PE=1 SV=4" 9.64 2120.3 - 355695 - - - 2.3234 - 2.883 0.517 - 326.5 1 2 0 0.003 12 0 0 0 9.16E+06 1.40E+07 - - - 7.2381 1 221125_WJC_METTL3_EV_vs_WT_F05.10090.10090.3 1.04E-06 Dec-48 K.EVHTQAENAEFMR[166.11].N "sp|P09601|HMOX1_HUMAN,tr|B1AHA8|B1AHA8_HUMAN,tr|A0A7I2V3I1|A0A7I2V3I1_HUMAN,tr|A0A7I2V277|A0A7I2V277_HUMAN" 4 1570.7074 1.8 62492 10090 3 1570.706415 524.5764 Heme oxygenase 1 OS=Homo sapiens OX=9606 GN=HMOX1 PE=1 SV=1 4.75 2120.4 - 205788 - - - -0.6023 - 2.322 0.523 - 286 1 2 0 -0.0009 13 0 0 0 3.68E+06 2.05E+06 - - - 6.6547 0.9999 221125_WJC_METTL3_EV_vs_WT_F05.10094.10094.3 0.241 13/44 R.LFGEVTR[166.11]PTNSK[136.11].S "sp|Q9Y291|RT33_HUMAN,tr|C9JBY7|C9JBY7_HUMAN" 2 1365.7371 1.06 62494 10094 3 1365.737488 456.253 "28S ribosomal protein S33, mitochondrial OS=Homo sapiens OX=9606 GN=MRPS33 PE=1 SV=1" 8.75 2121 - 1.56E+06 - - - 0.2592 - 2.57 0.346 - 195.4 1 2 0 0.0004 12 0 0 0 5.54E+07 5.21E+07 - - - 5.0138 0.9998 221125_WJC_METTL3_EV_vs_WT_F05.10095.10095.2 8.28E-06 20-Dec K.NSDEADLVPAK[136.11].E "sp|P83916|CBX1_HUMAN,tr|J3KS05|J3KS05_HUMAN,tr|B5MD17|B5MD17_HUMAN" 3 1165.5706 1.43 62495 10095 2 1165.572272 583.7926 Chromobox protein homolog 1 OS=Homo sapiens OX=9606 GN=CBX1 PE=1 SV=1 4.03 2121.1 - 1.32E+06 - - - 1.407 - 2.231 0.496 - 421.7 1 2 0 0.0016 11 0 0 0 7.04E+07 4.92E+07 - - - 4.8748 0.9998 221125_WJC_METTL3_EV_vs_WT_F05.10096.10096.2 0.0003 20-Nov K.GSQFGQSC[160.03]C[160.03]LR[166.11].A "sp|P07814|SYEP_HUMAN,tr|V9GYZ6|V9GYZ6_HUMAN" 2 1308.5579 0.98 62496 10096 2 1308.559958 655.2862 Bifunctional glutamate\proline--tRNA ligase OS=Homo sapiens OX=9606 GN=EPRS1 PE=1 SV=5 8.07 2121.1 - 1.79E+06 - - - 1.6033 - 2.092 0.538 - 455.4 1 2 0 0.0021 11 0 0 0 1.64E+07 1.68E+07 - - - 5.0108 1 221125_WJC_METTL3_EV_vs_WT_F05.10099.10099.2 6.09E-08 14/26 R.FLTNGPSSSPGQER.E "sp|Q7Z406|MYH14_HUMAN,tr|M0QY43|M0QY43_HUMAN" 2 1475.7005 1.05 62499 10099 2 1475.703696 738.8575 Myosin-14 OS=Homo sapiens OX=9606 GN=MYH14 PE=1 SV=2 6 2121.5 - 419662 - - - 2.1854 - 2.756 0.652 - 693.6 1 2 0 0.0032 14 0 0 0 3.44E+06 3.28E+06 - - - 6.3997 0.9969 221125_WJC_METTL3_EV_vs_WT_F05.10102.10102.2 0.00917 26-Aug R.SLLEGEGSSGGGGR.G "sp|P13645|K1C10_HUMAN,tr|A0A1B0GVI3|A0A1B0GVI3_HUMAN" 2 1261.5899 2.16 62502 10102 2 1261.594468 631.8022 "Keratin, type I cytoskeletal 10 OS=Homo sapiens OX=9606 GN=KRT10 PE=1 SV=6" 4.53 2121.9 - 86277.5 - - - 3.6541 - 1.484 0.43 - 205.2 1 2 0 0.0046 14 0 0 0 1.10E+06 5.10E+05 - - - 3.2061 0.9993 221125_WJC_METTL3_EV_vs_WT_F05.10104.10104.3 0.0293 Nov-48 R.GLPPHTTDQDLVK.L "sp|P29558|RBMS1_HUMAN,tr|E7ETU5|E7ETU5_HUMAN,tr|F6Y5H0|F6Y5H0_HUMAN,tr|E7EPF2|E7EPF2_HUMAN" 4 1419.7358 2.06 62503 10104 3 1419.737265 474.2525 "RNA-binding motif, single-stranded-interacting protein 1 OS=Homo sapiens OX=9606 GN=RBMS1 PE=1 SV=3" 5.21 2122.1 - 774930 - - - 1.0361 - 1.82 0.309 - 101.6 1 2 0 0.0015 13 0 0 0 2.14E+07 1.04E+07 - - - 3.6083 0.9995 221125_WJC_METTL3_EV_vs_WT_F05.10106.10106.2 0.00104 12-Aug R.SNWQNYR.Q "sp|Q9Y2W1|TR150_HUMAN,tr|A0A3B3ITZ9|A0A3B3ITZ9_HUMAN" 2 966.4308 2.46 62504 10106 2 966.432171 484.2227 Thyroid hormone receptor-associated protein 3 OS=Homo sapiens OX=9606 GN=THRAP3 PE=1 SV=2 8.46 2122.3 - 8.28E+06 - - - 1.4414 - 1.748 0.384 - 414.6 1 2 0 0.0014 7 0 0 0 2.63E+09 1.07E+09 - - - 3.6463 0.9993 221125_WJC_METTL3_EV_vs_WT_F05.10107.10107.2 0.000309 12-Aug R.SNWQNYR[166.11].Q "sp|Q9Y2W1|TR150_HUMAN,tr|A0A3B3ITZ9|A0A3B3ITZ9_HUMAN" 2 976.439 2.46 62505 10107 2 976.440132 489.2268 Thyroid hormone receptor-associated protein 3 OS=Homo sapiens OX=9606 GN=THRAP3 PE=1 SV=2 8.46 2122.4 - 4.51E+06 - - - 1.1102 - 1.849 0.278 - 395.9 1 2 0 0.0011 7 0 0 0 2.63E+09 1.07E+09 - - - 3.0415 0.9965 221125_WJC_METTL3_EV_vs_WT_F05.10109.10109.3 1.28 Nov-60 K.SIGTANRPMGAGEALR.R "sp|Q12906|ILF3_HUMAN,tr|K7EQR9|K7EQR9_HUMAN" 2 1599.8151 1.29 62507 10109 3 1599.817563 534.279 Interleukin enhancer-binding factor 3 OS=Homo sapiens OX=9606 GN=ILF3 PE=1 SV=3 9.31 2122.6 - 1.07E+06 - - - 1.5246 - 1.532 0.275 - 87.9 1 2 0 0.0024 16 0 0 0 3.00E+07 2.33E+07 - - - 2.6998 0.9998 221125_WJC_METTL3_EV_vs_WT_F05.10110.10110.3 2.52E-05 16/60 K.SIGTANR[166.11]PMGAGEALR[166.11].R "sp|Q12906|ILF3_HUMAN,tr|K7EQR9|K7EQR9_HUMAN" 2 1619.8317 1.3 62508 10110 3 1619.835468 540.9512 Interleukin enhancer-binding factor 3 OS=Homo sapiens OX=9606 GN=ILF3 PE=1 SV=3 9.31 2122.7 - 932378 - - - 2.3484 - 2.097 0.432 - 207.7 1 2 0 0.0038 16 0 0 0 3.02E+07 2.33E+07 - - - 5.2554 1 221125_WJC_METTL3_EV_vs_WT_F05.10112.10112.2 2.40E-07 14/20 K.AADSLQQNLQR.D "sp|Q1ED39|KNOP1_HUMAN,tr|H3BNU8|H3BNU8_HUMAN" 2 1242.6317 1.24 62510 10112 2 1242.631852 622.3231 Lysine-rich nucleolar protein 1 OS=Homo sapiens OX=9606 GN=KNOP1 PE=1 SV=1 5.88 2122.9 - 489269 - - - 0.1521 - 2.968 0.526 - 1081.5 1 2 0 0.0002 11 0 0 0 1.43E+07 1.15E+07 - - - 5.869 1 221125_WJC_METTL3_EV_vs_WT_F05.10113.10113.2 5.44E-06 20-Nov K.AADSLQQNLQR[166.11].D "sp|Q1ED39|KNOP1_HUMAN,tr|H3BNU8|H3BNU8_HUMAN" 2 1252.6399 1.24 62511 10113 2 1252.644149 627.3272 Lysine-rich nucleolar protein 1 OS=Homo sapiens OX=9606 GN=KNOP1 PE=1 SV=1 5.88 2123.1 - 403800 - - - 3.3657 - 2.844 0.531 - 617.6 1 2 0 0.0042 11 0 0 0 1.43E+07 1.15E+07 - - - 5.7892 0.8876 221125_WJC_METTL3_EV_vs_WT_F05.10114.10114.2 4.18 14-May R.EYTINIHK.R "sp|P62899|RL31_HUMAN,tr|B7Z4C8|B7Z4C8_HUMAN,tr|B7Z4E3|B7Z4E3_HUMAN,tr|B8ZZK4|B8ZZK4_HUMAN,tr|H7C2W9|H7C2W9_HUMAN,tr|C9JU56|C9JU56_HUMAN" 6 1016.5291 1.01 62512 10114 2 1016.525224 509.2718 60S ribosomal protein L31 OS=Homo sapiens OX=9606 GN=RPL31 PE=1 SV=1 6.85 2123.2 - 191573 - - - -3.8081 - 1.214 0.132 - 107.1 4 2 0 -0.0039 8 0 0 0 1.62E+07 1.61E+07 - - - 0.3307 0.9996 221125_WJC_METTL3_EV_vs_WT_F05.10117.10117.2 0.0595 28-Sep R.AAAAALSQQQSLQER[166.11].L sp|Q8WUQ7|CATIN_HUMAN 1 1580.8146 0.94 62515 10117 2 1580.813505 791.4146 Cactin OS=Homo sapiens OX=9606 GN=CACTIN PE=1 SV=3 6.05 2123.6 - 118003 - - - -0.6946 - 1.915 0.378 - 229.9 1 2 0 -0.0011 15 0 0 0 8.83E+05 9.38E+05 - - - 3.4299 0.9997 221125_WJC_METTL3_EV_vs_WT_F05.10119.10119.2 2.04E-05 24-Nov K.GPGEVAGTVTGQK[136.11].R "sp|Q86U44|MTA70_HUMAN,tr|F5H6D8|F5H6D8_HUMAN,tr|H0YFV6|H0YFV6_HUMAN,tr|B4DTN4|B4DTN4_HUMAN" 4 1207.6288 0.06 62516 10119 2 1207.631214 604.8217 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 6 2123.8 - 242313 - - - 1.9857 - 2.217 0.486 - 153 1 2 0 0.0024 13 0 0 0 4.65E+05 7.86E+06 - - - 4.6732 0.9998 221125_WJC_METTL3_EV_vs_WT_F05.10121.10121.2 0.156 18-Oct R.YPDGIISK[136.11]PK[136.11].N sp|Q86U44|MTA70_HUMAN 1 1132.6463 0.001 62517 10121 2 1132.646876 567.3304 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 8.5 2124 - 2.72E+06 - - - 0.4997 - 1.966 0.473 - 352.5 1 2 0 0.0006 10 0 0 0 0.00E+00 8.79E+07 - - - 4.4213 0.9998 221125_WJC_METTL3_EV_vs_WT_F05.10122.10122.3 0.00152 Sep-40 K.AIEVLSDEHAR.E sp|Q9HCS7|SYF1_HUMAN 1 1238.6255 2.29 62518 10122 3 1238.625384 413.8824 Pre-mRNA-splicing factor SYF1 OS=Homo sapiens OX=9606 GN=XAB2 PE=1 SV=2 4.65 2124.1 - 1.07E+06 - - - -0.1058 - 1.923 0.396 - 98.4 1 2 0 -0.0001 11 0 0 0 1.24E+07 5.42E+06 - - - 4.8126 0.9942 221125_WJC_METTL3_EV_vs_WT_F05.10123.10123.2 0.386 14-Jul R.EYTINIHK[136.11].R "sp|P62899|RL31_HUMAN,tr|B7Z4C8|B7Z4C8_HUMAN,tr|B7Z4E3|B7Z4E3_HUMAN,tr|B8ZZK4|B8ZZK4_HUMAN,tr|H7C2W9|H7C2W9_HUMAN,tr|C9JU56|C9JU56_HUMAN" 6 1024.5433 1 62519 10123 2 1024.544072 513.2789 60S ribosomal protein L31 OS=Homo sapiens OX=9606 GN=RPL31 PE=1 SV=1 6.85 2124.2 - 997796 - - - 0.7584 - 1.236 0.195 - 125.1 1 2 0 0.0008 8 0 0 0 1.62E+07 1.62E+07 - - - 1.12 1 221125_WJC_METTL3_EV_vs_WT_F05.10124.10124.2 6.06E-07 13/20 K.FSGDLDDQTC[160.03]R[166.11].E sp|P05455|LA_HUMAN 1 1322.5437 0.95 62520 10124 2 1322.54609 662.2791 Lupus La protein OS=Homo sapiens OX=9606 GN=SSB PE=1 SV=2 3.93 2124.4 - 684579 - - - 1.8449 - 2.548 0.643 - 519 1 2 0 0.0024 11 0 0 0 1.78E+07 1.88E+07 - - - 6.3197 0.9999 221125_WJC_METTL3_EV_vs_WT_F05.10125.10125.3 1.43E-05 15/44 R.ARPAEVGGMQLR.F "sp|P33316|DUT_HUMAN,tr|H0YNJ9|H0YNJ9_HUMAN,tr|H0YMM5|H0YMM5_HUMAN,tr|H0YKC5|H0YKC5_HUMAN,tr|H0YKI0|H0YKI0_HUMAN,tr|H0YNW5|H0YNW5_HUMAN" 6 1283.6768 0.65 62521 10125 3 1283.680029 428.8996 "Deoxyuridine 5'-triphosphate nucleotidohydrolase, mitochondrial OS=Homo sapiens OX=9606 GN=DUT PE=1 SV=4" 9.64 2124.5 - 602267 - - - 2.485 - 2.653 0.495 - 316 1 2 0 0.0032 12 0 0 0 9.16E+06 1.40E+07 - - - 6.7623 0.9992 221125_WJC_METTL3_EV_vs_WT_F05.10131.10131.2 0.000437 26-Jul R.LDAEPR[166.11]PPPTQEAA.- "sp|Q9Y285|SYFA_HUMAN,tr|K7ER00|K7ER00_HUMAN" 2 1500.7448 1.95 62527 10131 2 1500.747301 751.3797 Phenylalanine--tRNA ligase alpha subunit OS=Homo sapiens OX=9606 GN=FARSA PE=1 SV=3 4.14 2125.2 - 170506 - - - 1.6718 - 1.644 0.402 - 79.8 1 2 0 0.0025 14 0 0 0 2.82E+07 1.45E+07 - - - 3.2569 0.9999 221125_WJC_METTL3_EV_vs_WT_F05.10134.10134.3 0.000169 14/44 R.LFGEVTRPTNSK.S "sp|Q9Y291|RT33_HUMAN,tr|C9JBY7|C9JBY7_HUMAN" 2 1347.7147 1.06 62528 10134 3 1347.715731 450.2455 "28S ribosomal protein S33, mitochondrial OS=Homo sapiens OX=9606 GN=MRPS33 PE=1 SV=1" 8.75 2125.7 - 3.82E+06 - - - 0.7917 - 2.369 0.36 - 190.2 1 2 0 0.0011 12 0 0 0 5.53E+07 5.20E+07 - - - 4.944 0.9997 221125_WJC_METTL3_EV_vs_WT_F05.10135.10135.2 0.00136 20-Oct K.NSDEADLVPAK.E "sp|P83916|CBX1_HUMAN,tr|J3KS05|J3KS05_HUMAN,tr|B5MD17|B5MD17_HUMAN" 3 1157.5564 1.43 62529 10135 2 1157.557571 579.7855 Chromobox protein homolog 1 OS=Homo sapiens OX=9606 GN=CBX1 PE=1 SV=1 4.03 2125.7 - 3.03E+06 - - - 0.984 - 1.89 0.413 - 257.8 1 2 0 0.0011 11 0 0 0 7.05E+07 4.93E+07 - - - 3.8132 0.9976 221125_WJC_METTL3_EV_vs_WT_F05.10139.10139.3 0.0433 Oct-40 K.AIEVLSDEHAR[166.11].E sp|Q9HCS7|SYF1_HUMAN 1 1248.6338 2.29 62533 10139 3 1248.632466 417.2185 Pre-mRNA-splicing factor SYF1 OS=Homo sapiens OX=9606 GN=XAB2 PE=1 SV=2 4.65 2126.1 - 426172 - - - -1.0564 - 1.664 0.245 - 155.3 1 2 0 -0.0013 11 0 0 0 1.24E+07 5.42E+06 - - - 2.7178 0.9998 221125_WJC_METTL3_EV_vs_WT_F05.10140.10140.2 7.29E-05 14/22 R.LFGEVTRPTNSK.S "sp|Q9Y291|RT33_HUMAN,tr|C9JBY7|C9JBY7_HUMAN" 2 1347.7147 1.22 62534 10140 2 1347.716625 674.8646 "28S ribosomal protein S33, mitochondrial OS=Homo sapiens OX=9606 GN=MRPS33 PE=1 SV=1" 8.75 2126.3 - 365588 - - - 1.4551 - 2.313 0.464 - 634.8 1 2 0 0.002 12 0 0 0 5.15E+06 4.22E+06 - - - 4.6738 0.9985 221125_WJC_METTL3_EV_vs_WT_F05.10141.10141.2 0.0376 18-Aug R.ESQSVEEALK.K sp|P49915|GUAA_HUMAN 1 1118.5455 0.99 62535 10141 2 1118.543428 560.28 GMP synthase [glutamine-hydrolyzing] OS=Homo sapiens OX=9606 GN=GMPS PE=1 SV=1 4.25 2126.4 - 345546 - - - -1.8819 - 1.641 0.302 - 275.1 1 2 0 -0.0021 10 0 0 0 5.36E+06 5.45E+06 - - - 2.6535 0.9999 221125_WJC_METTL3_EV_vs_WT_F05.10145.10145.2 3.46E-07 20-Dec K.QEYVDYSESAK.K sp|O60832|DKC1_HUMAN 1 1317.5725 0.95 62539 10145 2 1317.57252 659.7935 H\ACA ribonucleoprotein complex subunit DKC1 OS=Homo sapiens OX=9606 GN=DKC1 PE=1 SV=3 4.14 2126.9 - 211288 - - - 0.0334 - 2.078 0.588 - 427.5 1 2 0 0 11 0 0 0 4.23E+06 4.47E+06 - - - 5.3626 0.9994 221125_WJC_METTL3_EV_vs_WT_F05.10147.10147.2 0.000432 20-Jul R.GTIADYQPDDK.A sp|Q99959|PKP2_HUMAN 1 1221.5513 1.25 62541 10147 2 1221.552232 611.7829 Plakophilin-2 OS=Homo sapiens OX=9606 GN=PKP2 PE=1 SV=2 3.93 2127.2 - 160558 - - - 0.7245 - 1.531 0.383 - 119.4 1 2 0 0.0009 11 0 0 0 3.28E+06 2.63E+06 - - - 3.0218 0.9849 221125_WJC_METTL3_EV_vs_WT_F05.10151.10151.2 2.72E-05 24-Oct S.ASSLGGGFGGGSR.G sp|P35527|K1C9_HUMAN 1 1108.5261 3.84 62543 10151 2 1108.525835 555.2703 "Keratin, type I cytoskeletal 9 OS=Homo sapiens OX=9606 GN=KRT9 PE=1 SV=3" 9.79 2127.7 - 526410 - - - -0.2706 - 1.972 0.404 - 264.1 1 1 0 -0.0003 13 0 0 0 4.83E+06 1.26E+06 - - - 3.7676 0.9999 221125_WJC_METTL3_EV_vs_WT_F05.10154.10154.3 0.115 13/36 R.LTYEIEDEKR.R sp|P15924|DESP_HUMAN 1 1294.6405 12.73 62546 10154 3 1294.641219 432.5541 Desmoplakin OS=Homo sapiens OX=9606 GN=DSP PE=1 SV=3 4.41 2128 - 583364 - - - 0.5585 - 2.238 0.361 - 256 1 2 0 0.0007 10 0 0 0 5.24E+07 4.12E+06 - - - 4.9172 0.9962 221125_WJC_METTL3_EV_vs_WT_F05.10155.10155.3 6.16E-06 Nov-40 L.GASEFC[160.03]LHTAR[166.11].Q sp|Q92947|GCDH_HUMAN 1 1257.58 1.09 62547 10155 3 1257.579931 420.2006 "Glutaryl-CoA dehydrogenase, mitochondrial OS=Homo sapiens OX=9606 GN=GCDH PE=1 SV=1" 6.74 2128.1 - 412897 - - - -0.0358 - 2.161 0.496 - 172.5 1 1 0 0 11 0 0 0 3.48E+06 3.19E+06 - - - 6.259 0.9936 221125_WJC_METTL3_EV_vs_WT_F05.10158.10158.2 0.00397 26-Jul K.GEPEAPPASGLASR.A "sp|O43248|HXC11_HUMAN,tr|J3KMZ0|J3KMZ0_HUMAN" 2 1337.6575 10.59 62550 10158 2 1337.663162 669.836 Homeobox protein Hox-C11 OS=Homo sapiens OX=9606 GN=HOXC11 PE=1 SV=1 4.53 2128.5 - 198895 - - - 4.2006 - 1.515 0.378 - 106 1 2 0 0.0056 14 0 0 0 5.51E+06 5.20E+05 - - - 2.8736 1 221125_WJC_METTL3_EV_vs_WT_F05.10160.10160.2 3.25E-07 20-Dec K.FSGDLDDQTC[160.03]R.E sp|P05455|LA_HUMAN 1 1312.5354 0.95 62551 10160 2 1312.536959 657.275 Lupus La protein OS=Homo sapiens OX=9606 GN=SSB PE=1 SV=2 3.93 2128.7 - 1.39E+06 - - - 1.203 - 2.453 0.682 - 430.6 1 2 0 0.0016 11 0 0 0 1.78E+07 1.88E+07 - - - 6.5052 0.985 221125_WJC_METTL3_EV_vs_WT_F05.10170.10170.3 0.309 Nov-40 K.LSSLNLDDHAK[136.11].K sp|P82673|RT35_HUMAN 1 1219.6288 1.18 62559 10170 3 1219.629876 407.5502 "28S ribosomal protein S35, mitochondrial OS=Homo sapiens OX=9606 GN=MRPS35 PE=1 SV=1" 5.21 2129.9 - 933264 - - - 0.8691 - 1.449 0.179 - 105.2 1 2 0 0.0011 11 0 0 0 1.59E+07 1.35E+07 - - - 1.589 0.9968 221125_WJC_METTL3_EV_vs_WT_F05.10173.10173.2 0.00473 20-Jul R.VEIIANDQGNR[166.11].L "sp|P11021|BIP_HUMAN,sp|P48741|HSP77_HUMAN,sp|P54652|HSP72_HUMAN,sp|P0DMV8|HS71A_HUMAN,sp|P34931|HS71L_HUMAN,sp|P11142|HSP7C_HUMAN,sp|P0DMV9|HS71B_HUMAN,sp|P17066|HSP76_HUMAN,tr|E9PQQ4|E9PQQ4_HUMAN,tr|E9PNE6|E9PNE6_HUMAN,tr|E9PKE3|E9PKE3_HUMAN,tr|A0A7P0TB36|A0A7P0TB36_HUMAN,tr|E9PLF4|E9PLF4_HUMAN,tr|A0A7P0TAI0|A0A7P0TAI0_HUMAN,tr|Q53FA3|Q53FA3_HUMAN,tr|E9PI65|E9PI65_HUMAN,tr|E9PK54|E9PK54_HUMAN,tr|E9PN25|E9PN25_HUMAN,tr|E9PPY6|E9PPY6_HUMAN,tr|E9PQK7|E9PQK7_HUMAN,tr|A0A0G2JIW1|A0A0G2JIW1_HUMAN" 21 1237.629 0.24 62562 10173 2 1237.633986 619.8218 Endoplasmic reticulum chaperone BiP OS=Homo sapiens OX=9606 GN=HSPA5 PE=1 SV=2 4.37 2130.3 - 308097 - - - 4.0012 - 1.814 0.381 - 144.6 1 2 0 0.005 11 0 0 0 2.26E+06 9.26E+06 - - - 3.4646 0.9969 221125_WJC_METTL3_EV_vs_WT_F05.10178.10178.3 0.00237 13/36 K.LFKPPQPPAR.M "sp|O15372|EIF3H_HUMAN,tr|B3KS98|B3KS98_HUMAN,tr|A0A087WZK9|A0A087WZK9_HUMAN" 3 1149.6659 2.9 62565 10178 3 1149.666405 384.2292 Eukaryotic translation initiation factor 3 subunit H OS=Homo sapiens OX=9606 GN=EIF3H PE=1 SV=1 11 2131 - 882475 - - - 0.4706 - 1.619 0.232 - 186.6 1 2 0 0.0005 10 0 0 0 1.79E+07 6.17E+06 - - - 2.5335 0.9995 221125_WJC_METTL3_EV_vs_WT_F05.10179.10179.2 0.657 18-Nov K.TALIHDGLAR[166.11].G sp|P25398|RS12_HUMAN 1 1075.6014 2.07 62566 10179 2 1075.60274 538.808 40S ribosomal protein S12 OS=Homo sapiens OX=9606 GN=RPS12 PE=1 SV=3 6.41 2131.1 - 527884 - - - 1.2802 - 2.047 0.326 - 541 1 2 0 0.0014 10 0 0 0 1.54E+07 7.43E+06 - - - 3.448 0.9997 221125_WJC_METTL3_EV_vs_WT_F05.10180.10180.2 5.87E-05 16-Sep K.NSSTYWEGK.A sp|P26639|SYTC_HUMAN 1 1070.4669 0.38 62567 10180 2 1070.468422 536.2407 "Threonine--tRNA ligase 1, cytoplasmic OS=Homo sapiens OX=9606 GN=TARS1 PE=1 SV=3" 6 2131.2 - 344919 - - - 1.4321 - 1.701 0.508 - 221.2 1 2 0 0.0015 9 0 0 0 5.37E+06 1.42E+07 - - - 4.3294 0.9999 221125_WJC_METTL3_EV_vs_WT_F05.10181.10181.2 1.13E-05 18-Sep R.LTYEIEDEKR.R sp|P15924|DESP_HUMAN 1 1294.6405 24.55 62568 10181 2 1294.641481 648.3275 Desmoplakin OS=Homo sapiens OX=9606 GN=DSP PE=1 SV=3 4.41 2131.4 - 288860 - - - 0.7608 - 2.109 0.532 - 349.3 1 2 0 0.001 10 0 0 0 4.94E+06 2.01E+05 - - - 5.053 0.9977 221125_WJC_METTL3_EV_vs_WT_F05.10182.10182.2 0.0718 20-Sep R.GTIADYQPDDK[136.11].A sp|Q99959|PKP2_HUMAN 1 1229.5655 1.23 62569 10182 2 1229.564251 615.79 Plakophilin-2 OS=Homo sapiens OX=9606 GN=PKP2 PE=1 SV=2 3.93 2131.5 - 203851 - - - -1.054 - 1.473 0.237 - 193.3 1 2 0 -0.0013 11 0 0 0 3.33E+06 2.70E+06 - - - 1.8388 0.9997 221125_WJC_METTL3_EV_vs_WT_F05.10186.10186.3 0.0379 14/40 K.MLPEIDQNKDR.M "sp|P78344|IF4G2_HUMAN,tr|H0Y3P2|H0Y3P2_HUMAN,tr|D3DQV9|D3DQV9_HUMAN" 3 1357.666 2.09 62571 10186 3 1357.665795 453.5626 Eukaryotic translation initiation factor 4 gamma 2 OS=Homo sapiens OX=9606 GN=EIF4G2 PE=1 SV=1 4.56 2132 - 1.39E+06 - - - -0.151 - 2.389 0.418 - 347 1 2 1 -0.0002 11 0 0 0 1.94E+07 9.31E+06 - - - 5.6742 0.9917 221125_WJC_METTL3_EV_vs_WT_F05.10187.10187.3 0.00037 Nov-48 K.VC[160.03]GHTYEEDAIVR[166.11].M "sp|Q96MF7|NSE2_HUMAN,tr|E5RFJ1|E5RFJ1_HUMAN" 2 1557.7121 1.18 62572 10187 3 1557.701961 520.2446 E3 SUMO-protein ligase NSE2 OS=Homo sapiens OX=9606 GN=NSMCE2 PE=1 SV=2 4.65 2132.1 - 6.11E+06 - - - -6.5166 - 1.581 0.437 - 60 1 2 0 -0.0102 13 0 0 0 1.54E+07 1.31E+07 - - - 4.6512 0.9966 221125_WJC_METTL3_EV_vs_WT_F05.10191.10191.2 1.93 14-Aug R.R[166.11]EEFVSIK[136.11].R "sp|O43663|PRC1_HUMAN,tr|H0YM42|H0YM42_HUMAN" 2 1024.5672 1.18 62576 10191 2 1024.568576 513.2909 Protein regulator of cytokinesis 1 OS=Homo sapiens OX=9606 GN=PRC1 PE=1 SV=2 6.14 2132.6 - 335648 - - - 1.3284 - 1.675 0.152 - 256.3 1 2 0 0.0014 8 0 0 0 3.21E+06 2.73E+06 - - - 1.7189 0.9963 221125_WJC_METTL3_EV_vs_WT_F05.10192.10192.2 0.0357 16-Jul K.KIFEYETQR.R "sp|P50402|EMD_HUMAN,tr|A0A804HLA2|A0A804HLA2_HUMAN,tr|A0A804HIV7|A0A804HIV7_HUMAN" 3 1212.6139 1.61 62577 10192 2 1212.616123 607.3142 Emerin OS=Homo sapiens OX=9606 GN=EMD PE=1 SV=1 6.14 2132.7 - 287417 - - - 1.8431 - 1.514 0.223 - 177.1 1 2 0 0.0022 9 0 0 0 3.89E+06 2.42E+06 - - - 1.8873 0.9999 221125_WJC_METTL3_EV_vs_WT_F05.10202.10202.3 2.83E-05 13/44 R.SFPIEQSSHPVR.S "sp|Q9H1Z4|WDR13_HUMAN,tr|A0A087X091|A0A087X091_HUMAN" 2 1382.6943 0.37 62585 10202 3 1382.696266 461.9054 WD repeat-containing protein 13 OS=Homo sapiens OX=9606 GN=WDR13 PE=1 SV=2 6.47 2134 - 2.13E+06 - - - 1.4486 - 2.345 0.448 - 146.3 1 2 0 0.002 12 0 0 0 2.87E+07 7.66E+07 - - - 5.8966 0.9984 221125_WJC_METTL3_EV_vs_WT_F05.10203.10203.3 0.62 Nov-40 K.GTEITHAVVIK.K "sp|Q99613|EIF3C_HUMAN,sp|B5ME19|EIFCL_HUMAN" 2 1166.6659 0.89 62586 10203 3 1166.666502 389.8959 Eukaryotic translation initiation factor 3 subunit C OS=Homo sapiens OX=9606 GN=EIF3C PE=1 SV=1 6.75 2134.1 - 978351 - - - 0.4963 - 2.15 0.204 - 131.7 1 2 0 0.0006 11 0 0 0 1.16E+07 1.31E+07 - - - 2.9888 0.9996 221125_WJC_METTL3_EV_vs_WT_F05.10205.10205.2 0.00134 16-Jul K.EDTEEYNLR[166.11].D "sp|P51991|ROA3_HUMAN,tr|A0A7I2V5D8|A0A7I2V5D8_HUMAN,tr|A0A7I2V2R3|A0A7I2V2R3_HUMAN,tr|A0A7I2V4J6|A0A7I2V4J6_HUMAN,tr|A0A7I2V4G0|A0A7I2V4G0_HUMAN,tr|A0A7I2V402|A0A7I2V402_HUMAN" 6 1177.5127 1.21 62588 10205 2 1177.514285 589.7636 Heterogeneous nuclear ribonucleoprotein A3 OS=Homo sapiens OX=9606 GN=HNRNPA3 PE=1 SV=2 4 2134.3 - 530154 - - - 1.3741 - 1.667 0.429 - 157.3 1 2 0 0.0016 9 0 0 0 6.53E+06 5.38E+06 - - - 3.6875 0.9993 221125_WJC_METTL3_EV_vs_WT_F05.10206.10206.2 0.00524 16-Aug K.TYLLPDNHK.T sp|O00443|P3C2A_HUMAN 1 1099.5662 1.4 62589 10206 2 1099.567503 550.7904 Phosphatidylinositol 4-phosphate 3-kinase C2 domain-containing subunit alpha OS=Homo sapiens OX=9606 GN=PIK3C2A PE=1 SV=2 6.41 2134.4 - 387048 - - - 1.1768 - 1.579 0.357 - 221.8 1 2 0 0.0013 9 0 0 0 5.35E+06 3.81E+06 - - - 2.9989 0.9997 221125_WJC_METTL3_EV_vs_WT_F05.10207.10207.2 0.00351 16-Sep K.TYLLPDNHK[136.11].T sp|O00443|P3C2A_HUMAN 1 1107.5804 1.37 62590 10207 2 1107.581225 554.7975 Phosphatidylinositol 4-phosphate 3-kinase C2 domain-containing subunit alpha OS=Homo sapiens OX=9606 GN=PIK3C2A PE=1 SV=2 6.41 2134.5 - 378012 - - - 0.7367 - 1.801 0.402 - 276.3 1 2 0 0.0008 9 0 0 0 5.29E+06 3.87E+06 - - - 3.712 0.9997 221125_WJC_METTL3_EV_vs_WT_F05.10208.10208.2 0.000302 18-Aug K.LLNTVEETTK.D "sp|P52732|KIF11_HUMAN,tr|A0A7I2YQY4|A0A7I2YQY4_HUMAN,tr|A0A7I2V3A9|A0A7I2V3A9_HUMAN" 3 1146.6132 3.06 62591 10208 2 1146.614835 574.3139 Kinesin-like protein KIF11 OS=Homo sapiens OX=9606 GN=KIF11 PE=1 SV=2 4.53 2134.7 - 316791 - - - 1.4094 - 1.952 0.463 - 163.1 1 2 0 0.0016 10 0 0 0 2.88E+06 9.42E+05 - - - 4.3272 0.9994 221125_WJC_METTL3_EV_vs_WT_F05.10210.10210.3 0.0367 Sep-36 R.LTYEIEDEK[136.11]R[166.11].R sp|P15924|DESP_HUMAN 1 1312.663 16 62593 10210 3 1312.663399 438.5616 Desmoplakin OS=Homo sapiens OX=9606 GN=DSP PE=1 SV=3 4.41 2134.9 - 249133 - - - 0.3299 - 1.564 0.347 - 117.7 1 2 0 0.0004 10 0 0 0 4.61E+07 2.88E+06 - - - 3.7147 0.9996 221125_WJC_METTL3_EV_vs_WT_F05.10211.10211.2 0.000235 22-Sep K.QPTPQPPVDC[160.03]VK.T sp|P23490|LORI_HUMAN 1 1364.6758 999 62594 10211 2 1364.673351 683.3452 Loricrin OS=Homo sapiens OX=9606 GN=LORICRIN PE=1 SV=2 5.83 2135.1 - 224739 - - - -1.8209 - 1.973 0.433 - 239.1 1 2 0 -0.0025 12 0 0 0 3.42E+06 0.00E+00 - - - 4.0264 0.9992 221125_WJC_METTL3_EV_vs_WT_F05.10213.10213.2 0.0183 18-Aug R.QLLQEQESVK.Q sp|P15924|DESP_HUMAN 1 1200.635 2.25 62596 10213 2 1200.635787 601.3248 Desmoplakin OS=Homo sapiens OX=9606 GN=DSP PE=1 SV=3 4.53 2135.3 - 189434 - - - 0.6413 - 1.506 0.338 - 172.7 1 2 0 0.0008 10 0 0 0 1.33E+06 5.89E+05 - - - 2.6801 0.7694 221125_WJC_METTL3_EV_vs_WT_F05.10218.10218.2 1 20-Jul R.DFYSPLVPDSM.K sp|P57739|CLD2_HUMAN 1 1269.5587 - 62599 10218 2 1269.557852 635.7866 Claudin-2 OS=Homo sapiens OX=9606 GN=CLDN2 PE=1 SV=1 3.56 2136 - 1.46E+06 - - - -0.7002 - 1.292 0.193 - 85.8 1 1 0 -0.0009 11 0 0 0 - - - - - 1.1593 0.9999 221125_WJC_METTL3_EV_vs_WT_F05.10219.10219.3 0.000136 14/44 R.SFPIEQSSHPVR[166.11].S "sp|Q9H1Z4|WDR13_HUMAN,tr|A0A087X091|A0A087X091_HUMAN" 2 1392.7025 0.4 62600 10219 3 1392.701594 465.2415 WD repeat-containing protein 13 OS=Homo sapiens OX=9606 GN=WDR13 PE=1 SV=2 6.47 2136 - 1.12E+06 - - - -0.6742 - 2.475 0.393 - 242.3 1 2 0 -0.0009 12 0 0 0 2.66E+07 6.70E+07 - - - 5.4333 1 221125_WJC_METTL3_EV_vs_WT_F05.10221.10221.2 9.53E-09 13/22 R.C[160.03]VANNQVETLEK.L "sp|P42704|LPPRC_HUMAN,tr|A0A804HI14|A0A804HI14_HUMAN,tr|A0A804HL40|A0A804HL40_HUMAN,tr|A0A804HKJ0|A0A804HKJ0_HUMAN,tr|A0A804HKR3|A0A804HKR3_HUMAN,tr|A0A804HIN4|A0A804HIN4_HUMAN,tr|A0A804HJG8|A0A804HJG8_HUMAN,tr|A0A804HLG8|A0A804HLG8_HUMAN,tr|A0A804HHY9|A0A804HHY9_HUMAN,tr|A0A804HI44|A0A804HI44_HUMAN,tr|A0A804HI40|A0A804HI40_HUMAN,tr|A0A804HJZ1|A0A804HJZ1_HUMAN,tr|A0A804HIQ7|A0A804HIQ7_HUMAN,tr|A0A804HK30|A0A804HK30_HUMAN,tr|A0A804HKI2|A0A804HKI2_HUMAN,tr|A0A804HJI0|A0A804HJI0_HUMAN,tr|A0A804HIG4|A0A804HIG4_HUMAN" 17 1403.6715 1.07 62602 10221 2 1403.673734 702.843 "Leucine-rich PPR motif-containing protein, mitochondrial OS=Homo sapiens OX=9606 GN=LRPPRC PE=1 SV=3" 4.53 2136.3 - 713780 - - - 1.6065 - 2.554 0.651 - 377.8 1 2 0 0.0023 12 0 0 0 1.38E+07 1.28E+07 - - - 6.3157 0.9993 221125_WJC_METTL3_EV_vs_WT_F05.10222.10222.2 0.00123 16-Sep R.HYPVFENPK[136.11].Q "sp|P55265|DSRAD_HUMAN,tr|A0A3B3IRQ9|A0A3B3IRQ9_HUMAN,tr|A0A3B3ISU1|A0A3B3ISU1_HUMAN,tr|A0A7P0Z4K3|A0A7P0Z4K3_HUMAN,tr|A0A7P0Z4F9|A0A7P0Z4F9_HUMAN" 5 1137.5698 5.55 62603 10222 2 1137.572558 569.7922 Double-stranded RNA-specific adenosine deaminase OS=Homo sapiens OX=9606 GN=ADAR PE=1 SV=4 6.75 2136.4 - 711226 - - - 2.3858 - 1.659 0.454 - 305.6 1 2 0 0.0027 9 0 0 0 9.45E+07 1.70E+07 - - - 3.8579 0.9985 221125_WJC_METTL3_EV_vs_WT_F05.10224.10224.2 0.0454 16-Aug R.FTEYETQVK.V "sp|Q13148|TADBP_HUMAN,tr|A0A087WX67|A0A087WX67_HUMAN,tr|A0A087WX29|A0A087WX29_HUMAN,tr|G3V162|G3V162_HUMAN,tr|A0A087WV68|A0A087WV68_HUMAN,tr|A0A087WXV3|A0A087WXV3_HUMAN,tr|A0A087WYY0|A0A087WYY0_HUMAN,tr|K7EN94|K7EN94_HUMAN,tr|A0A0A0N0M3|A0A0A0N0M3_HUMAN,tr|A0A087WW61|A0A087WW61_HUMAN,tr|B1AKP7|B1AKP7_HUMAN,tr|K7EJM5|K7EJM5_HUMAN,tr|A0A087WXQ5|A0A087WXQ5_HUMAN,tr|A0A087X260|A0A087X260_HUMAN" 14 1143.5448 0.8 62605 10224 2 1143.546711 572.7797 TAR DNA-binding protein 43 OS=Homo sapiens OX=9606 GN=TARDBP PE=1 SV=1 4.53 2136.6 - 499514 - - - 1.6667 - 1.454 0.33 - 193.8 1 2 0 0.0019 9 0 0 0 3.61E+06 4.50E+06 - - - 2.5607 0.9993 221125_WJC_METTL3_EV_vs_WT_F05.10229.10229.2 5.79E-08 13/24 K.EAPSPTC[160.03]PDLGAK.S sp|O00257|CBX4_HUMAN 1 1341.6235 2.37 62610 10229 2 1341.628478 671.819 E3 SUMO-protein ligase CBX4 OS=Homo sapiens OX=9606 GN=CBX4 PE=1 SV=3 4.37 2137.3 - 280494 - - - 3.7358 - 2.371 0.566 - 546.3 1 2 0 0.005 13 0 0 0 3.77E+06 1.59E+06 - - - 5.4356 0.9996 221125_WJC_METTL3_EV_vs_WT_F05.10230.10230.2 0.000251 24-Aug K.EAPSPTC[160.03]PDLGAK[136.11].S sp|O00257|CBX4_HUMAN 1 1349.6377 2.29 62611 10230 2 1349.63837 675.8261 E3 SUMO-protein ligase CBX4 OS=Homo sapiens OX=9606 GN=CBX4 PE=1 SV=3 4.37 2137.4 - 172687 - - - 0.5216 - 1.564 0.432 - 162.9 1 2 0 0.0007 13 0 0 0 3.45E+06 1.51E+06 - - - 3.3794 0.9996 221125_WJC_METTL3_EV_vs_WT_F05.10231.10231.2 1.19E-05 Oct-38 R.AVAAVAATGPASAPGPGGGR.S sp|O75474|FRAT2_HUMAN 1 1633.8536 2.77 62612 10231 2 1633.858209 817.9341 GSK-3-binding protein FRAT2 OS=Homo sapiens OX=9606 GN=FRAT2 PE=2 SV=3 9.79 2137.6 - 120048 - - - 2.8099 - 2.456 0.555 - 313.5 1 2 0 0.0046 20 0 0 0 9.48E+05 3.42E+05 - - - 5.3479 0.9488 221125_WJC_METTL3_EV_vs_WT_F05.10232.10232.2 1.21 24-Mar R.GEAVC[160.03]PTC[160.03]NVVTR[166.11].K sp|Q96KM6|Z512B_HUMAN 1 1471.6787 0.82 62613 10232 2 1471.683101 736.8466 Zinc finger protein 512B OS=Homo sapiens OX=9606 GN=ZNF512B PE=1 SV=1 5.99 2137.7 - 98140.4 - - - 2.9877 - 0.833 0.263 - 36 1 2 0 0.0044 13 0 0 0 6.55E+05 8.00E+05 - - - 0.5132 1 221125_WJC_METTL3_EV_vs_WT_F05.10239.10239.2 1.62E-06 22-Sep K.STDTSC[160.03]QMAGLR.D "sp|Q9HBM1|SPC25_HUMAN,tr|C9JW94|C9JW94_HUMAN" 2 1325.5704 2.74 62619 10239 2 1325.572698 663.7925 Kinetochore protein Spc25 OS=Homo sapiens OX=9606 GN=SPC25 PE=1 SV=1 5.55 2138.3 - 1.20E+06 - - - 1.7449 - 2.243 0.638 - 328.7 1 2 0 0.0023 12 0 0 0 1.06E+07 3.88E+06 - - - 5.878 0.9686 221125_WJC_METTL3_EV_vs_WT_F05.10240.10240.3 4.97E-06 14/52 N.AAVQAVNAHSNILK.A "sp|Q16891|MIC60_HUMAN,tr|B9A067|B9A067_HUMAN,tr|C9J406|C9J406_HUMAN,tr|H7C463|H7C463_HUMAN" 4 1434.7943 1.6 62620 10240 3 1434.799 479.272 MICOS complex subunit MIC60 OS=Homo sapiens OX=9606 GN=IMMT PE=1 SV=1 8.8 2138.5 - 532448 - - - 3.2674 - 3.277 0.351 - 298.9 1 1 0 0.0047 14 0 0 0 4.05E+06 2.53E+06 - - - 5.6063 0.9933 221125_WJC_METTL3_EV_vs_WT_F05.10241.10241.3 0.00793 Sep-36 K.QQASHYLYVR[166.11].A sp|Q9Y3A4|RRP7A_HUMAN 1 1273.6443 1.23 62621 10241 3 1273.646087 425.5554 Ribosomal RNA-processing protein 7 homolog A OS=Homo sapiens OX=9606 GN=RRP7A PE=1 SV=2 8.6 2138.6 - 387166 - - - 1.4109 - 1.662 0.199 - 132.3 1 2 0 0.0018 10 0 0 0 4.20E+07 3.43E+07 - - - 2.2418 0.9996 221125_WJC_METTL3_EV_vs_WT_F05.10242.10242.2 6.87E-06 22-Nov K.SFDANGASTLSK.L "sp|Q9BTA9|WAC_HUMAN,tr|A0A7P0T961|A0A7P0T961_HUMAN,tr|J3QTA0|J3QTA0_HUMAN" 3 1196.5673 1.37 62622 10242 2 1196.571054 599.2909 WW domain-containing adapter protein with coiled-coil OS=Homo sapiens OX=9606 GN=WAC PE=1 SV=3 5.55 2138.7 - 340734 - - - 3.1114 - 2.282 0.608 - 282.1 1 2 0 0.0037 12 0 0 0 3.36E+06 2.46E+06 - - - 5.7014 0.9922 221125_WJC_METTL3_EV_vs_WT_F05.10243.10243.3 0.139 Sep-36 R.LQVTEHLPEK.L "sp|Q9NPL8|TIDC1_HUMAN,tr|C9JU35|C9JU35_HUMAN" 2 1192.6452 1.04 62623 10243 3 1192.645186 398.5557 "Complex I assembly factor TIMMDC1, mitochondrial OS=Homo sapiens OX=9606 GN=TIMMDC1 PE=1 SV=2" 5.4 2138.9 - 321803 - - - -0.0017 - 1.734 0.162 - 74.4 1 2 0 0 10 0 0 0 3.66E+06 3.50E+06 - - - 1.9536 0.9995 221125_WJC_METTL3_EV_vs_WT_F05.10244.10244.3 0.33 Dec-36 K.QQASHYLYVR.A sp|Q9Y3A4|RRP7A_HUMAN 1 1263.636 1.23 62624 10244 3 1263.636896 422.2193 Ribosomal RNA-processing protein 7 homolog A OS=Homo sapiens OX=9606 GN=RRP7A PE=1 SV=2 8.6 2139 - 316568 - - - 0.6932 - 2.089 0.287 - 267.9 1 2 0 0.0009 10 0 0 0 4.20E+07 3.43E+07 - - - 3.891 0.9997 221125_WJC_METTL3_EV_vs_WT_F05.10245.10245.2 3.83E-05 20-Dec R.FEDVVNQSSPK.N sp|Q01085|TIAR_HUMAN 1 1248.5986 1.68 62625 10245 2 1248.59554 625.3066 Nucleolysin TIAR OS=Homo sapiens OX=9606 GN=TIAL1 PE=1 SV=1 4.37 2139.1 - 307453 - - - -2.4764 - 2.213 0.509 - 458 1 2 0 -0.0031 11 0 0 0 4.51E+07 2.68E+07 - - - 4.9484 0.9985 221125_WJC_METTL3_EV_vs_WT_F05.10247.10247.2 0.00582 18-Aug K.AAPPQIPDTR[166.11].R sp|Q9HAF1|EAF6_HUMAN 1 1074.5697 1.39 62627 10247 2 1074.570736 538.2921 Chromatin modification-related protein MEAF6 OS=Homo sapiens OX=9606 GN=MEAF6 PE=1 SV=1 5.88 2139.4 - 157335 - - - 0.938 - 1.497 0.283 - 191.7 1 2 0 0.001 10 0 0 0 8.71E+07 6.26E+07 - - - 2.2571 1 221125_WJC_METTL3_EV_vs_WT_F05.10254.10254.2 3.01E-11 18/36 R.EAAAYSSGGGAAGAGLAGR.E "sp|P43694|GATA4_HUMAN,tr|A0A087WZ09|A0A087WZ09_HUMAN" 2 1592.7543 2.39 62633 10254 2 1592.754964 797.3844 Transcription factor GATA-4 OS=Homo sapiens OX=9606 GN=GATA4 PE=1 SV=2 6.1 2140.2 - 858632 - - - 0.4188 - 3.553 0.715 - 842.9 1 2 0 0.0007 19 0 0 0 1.15E+07 4.81E+06 - - - 7.4387 0.9083 221125_WJC_METTL3_EV_vs_WT_F05.10255.10255.2 0.89 16-Jul R.RGDVDEFKK.L "sp|Q9BPY3|F118B_HUMAN,tr|J3KP39|J3KP39_HUMAN,tr|G3V179|G3V179_HUMAN,tr|E9PMJ2|E9PMJ2_HUMAN,tr|E9PIM5|E9PIM5_HUMAN" 5 1092.5564 2.71 62634 10255 2 1092.559664 547.2855 Protein FAM118B OS=Homo sapiens OX=9606 GN=FAM118B PE=1 SV=1 6.12 2140.3 - 656528 - - - 3.0122 - 1.324 0.054 - 134.9 2 2 0 0.0033 9 0 0 0 2.32E+07 8.57E+06 - - - 0.1163 0.9757 221125_WJC_METTL3_EV_vs_WT_F05.10256.10256.2 0.00109 18-Sep K.AAPPQIPDTR.R sp|Q9HAF1|EAF6_HUMAN 1 1064.5615 1.14 62635 10256 2 1064.568877 533.288 Chromatin modification-related protein MEAF6 OS=Homo sapiens OX=9606 GN=MEAF6 PE=1 SV=1 5.88 2140.4 - 625326 - - - 6.9691 - 1.719 0.381 - 251.5 1 2 0 0.0074 10 0 0 0 4.28E+07 3.76E+07 - - - 3.3649 0.9999 221125_WJC_METTL3_EV_vs_WT_F05.10257.10257.2 2.14E-06 13/20 R.FEDVVNQSSPK[136.11].N sp|Q01085|TIAR_HUMAN 1 1256.6128 1.7 62636 10257 2 1256.613828 629.3137 Nucleolysin TIAR OS=Homo sapiens OX=9606 GN=TIAL1 PE=1 SV=1 4.37 2140.6 - 496843 - - - 0.7926 - 2.465 0.533 - 514.4 1 2 0 0.001 11 0 0 0 4.50E+07 2.65E+07 - - - 5.4181 0.9791 221125_WJC_METTL3_EV_vs_WT_F05.10262.10262.2 0.589 20-Jul K.K[136.11]LTELGTVDPK[136.11].N "sp|P46940|IQGA1_HUMAN,tr|H0YLE8|H0YLE8_HUMAN" 2 1215.7046 1 62641 10262 2 1215.70746 608.8596 Ras GTPase-activating-like protein IQGAP1 OS=Homo sapiens OX=9606 GN=IQGAP1 PE=1 SV=1 6.07 2141.2 - 168574 - - - 2.3904 - 1.146 0.196 - 138.8 1 2 0 0.0029 11 0 0 0 1.74E+06 1.73E+06 - - - 0.8564 0.9874 221125_WJC_METTL3_EV_vs_WT_F05.10263.10263.3 0.00455 Sep-36 K.GK[136.11]DMVVDIQR[166.11].R sp|Q9Y266|NUDC_HUMAN 1 1177.6244 1.19 62642 10263 3 1177.628177 393.5487 Nuclear migration protein nudC OS=Homo sapiens OX=9606 GN=NUDC PE=1 SV=1 5.96 2141.3 - 160898 - - - 3.1963 - 1.873 0.294 - 139 1 2 1 0.0038 10 0 0 0 6.45E+06 5.43E+06 - - - 3.6495 0.9997 221125_WJC_METTL3_EV_vs_WT_F05.10270.10270.2 5.10E-06 22-Sep R.AQATAQDPVFQK.L "sp|Q9Y4A5|TRRAP_HUMAN,tr|A0A2R8YFJ4|A0A2R8YFJ4_HUMAN,tr|H0Y4W2|H0Y4W2_HUMAN,tr|F2Z2U4|F2Z2U4_HUMAN" 4 1302.6568 1.08 62647 10270 2 1302.659585 652.3357 Transformation\transcription domain-associated protein OS=Homo sapiens OX=9606 GN=TRRAP PE=1 SV=3 5.88 2142.3 - 340459 - - - 2.1264 - 2.117 0.546 - 251.9 1 2 0 0.0028 12 0 0 0 3.69E+06 3.41E+06 - - - 5.0463 0.7804 221125_WJC_METTL3_EV_vs_WT_F05.10271.10271.3 0.000509 Nov-48 Y.SVHPGTVQSELVR.H "sp|Q8TC12|RDH11_HUMAN,tr|H0YIZ8|H0YIZ8_HUMAN,tr|G3V2G6|G3V2G6_HUMAN" 3 1407.747 0.73 62648 10271 3 1407.753128 470.2563 Retinol dehydrogenase 11 OS=Homo sapiens OX=9606 GN=RDH11 PE=1 SV=2 6.47 2142.4 - 313669 - - - 4.3339 - 2.066 0.344 - 231.5 1 1 0 0.0061 13 0 0 0 2.35E+06 3.24E+06 - - - 4.3409 0.9999 221125_WJC_METTL3_EV_vs_WT_F05.10273.10273.3 7.69E-05 13/52 K.VINQYQVVK[136.11]PTAER[166.11].T sp|Q14694|UBP10_HUMAN 1 1661.922 0.83 62650 10273 3 1661.92747 554.9813 Ubiquitin carboxyl-terminal hydrolase 10 OS=Homo sapiens OX=9606 GN=USP10 PE=1 SV=2 8.56 2142.7 - 230009 - - - 3.3064 - 2.582 0.537 - 214 1 2 0 0.0055 14 0 0 0 2.25E+06 2.71E+06 - - - 7.0463 0.9947 221125_WJC_METTL3_EV_vs_WT_F05.10275.10275.2 0.0516 24-May K.AMGQGLPDEEQEK.L "sp|Q9Y4W2|LAS1L_HUMAN,tr|A0A7I2V3Q3|A0A7I2V3Q3_HUMAN,tr|A0A7I2V4E5|A0A7I2V4E5_HUMAN" 3 1430.6348 1.23 62652 10275 2 1430.635945 716.3247 Ribosomal biogenesis protein LAS1L OS=Homo sapiens OX=9606 GN=LAS1L PE=1 SV=2 4 2142.9 - 177245 - - - 0.829 - 1.315 0.216 - 52.3 2 2 0 0.0012 13 0 0 0 2.77E+06 2.25E+06 - - - 1.2043 0.9991 221125_WJC_METTL3_EV_vs_WT_F05.10279.10279.2 0.000509 22-Sep R.AQATAQDPVFQK[136.11].L "sp|Q9Y4A5|TRRAP_HUMAN,tr|A0A2R8YFJ4|A0A2R8YFJ4_HUMAN,tr|H0Y4W2|H0Y4W2_HUMAN,tr|F2Z2U4|F2Z2U4_HUMAN" 4 1310.671 1.08 62655 10279 2 1310.672682 656.3428 Transformation\transcription domain-associated protein OS=Homo sapiens OX=9606 GN=TRRAP PE=1 SV=3 5.88 2143.4 - 472238 - - - 1.2719 - 1.713 0.325 - 221.2 1 2 0 0.0017 12 0 0 0 3.69E+06 3.41E+06 - - - 2.8571 0.9744 221125_WJC_METTL3_EV_vs_WT_F05.10282.10282.3 0.173 Dec-36 K.TYHALSNLPK[136.11].A "sp|O00231|PSD11_HUMAN,tr|J3QS13|J3QS13_HUMAN" 2 1150.6226 0.62 62657 10282 3 1150.620949 384.5481 26S proteasome non-ATPase regulatory subunit 11 OS=Homo sapiens OX=9606 GN=PSMD11 PE=1 SV=3 8.29 2143.7 - 2.06E+06 - - - -1.4418 - 1.542 0.141 - 131.3 1 2 0 -0.0017 10 0 0 0 2.27E+07 3.64E+07 - - - 1.3763 0.9993 221125_WJC_METTL3_EV_vs_WT_F05.10283.10283.3 0.000974 Nov-36 K.LQDVADSFK[136.11]K[136.11].L "sp|P0DJD0|RGPD1_HUMAN,sp|Q7Z3J3|RGPD4_HUMAN,sp|O14715|RGPD8_HUMAN,sp|P49792|RBP2_HUMAN,sp|P0DJD1|RGPD2_HUMAN,sp|A6NKT7|RGPD3_HUMAN,sp|Q99666|RGPD5_HUMAN,tr|A0A286YES2|A0A286YES2_HUMAN,tr|F8VYC4|F8VYC4_HUMAN,tr|J3KNE0|J3KNE0_HUMAN,tr|A0A1W2PNU4|A0A1W2PNU4_HUMAN,tr|J3KQ37|J3KQ37_HUMAN" 12 1165.6314 2.59 62658 10283 3 1165.633313 389.5511 RANBP2-like and GRIP domain-containing protein 1 OS=Homo sapiens OX=9606 GN=RGPD1 PE=2 SV=1 5.96 2143.8 - 1.02E+06 - - - 1.6506 - 1.895 0.311 - 95.9 1 2 0 0.0019 10 0 0 0 2.67E+07 1.03E+07 - - - 3.8736 0.9875 221125_WJC_METTL3_EV_vs_WT_F05.10284.10284.2 1.24 16-Jun R.R[166.11]GDVDEFK[136.11]K[136.11].L "sp|Q9BPY3|F118B_HUMAN,tr|J3KP39|J3KP39_HUMAN,tr|G3V179|G3V179_HUMAN,tr|E9PMJ2|E9PMJ2_HUMAN,tr|E9PIM5|E9PIM5_HUMAN" 5 1118.593 2.69 62659 10284 2 1118.593517 560.3038 Protein FAM118B OS=Homo sapiens OX=9606 GN=FAM118B PE=1 SV=1 6.12 2143.9 - 850235 - - - 0.4237 - 1.317 0.11 - 95.8 2 2 0 0.0005 9 0 0 0 2.30E+07 8.57E+06 - - - 0.5155 0.9997 221125_WJC_METTL3_EV_vs_WT_F05.10285.10285.3 5.37E-07 15/48 K.TILPGGVADQHGR.L "sp|O75970|MPDZ_HUMAN,tr|F5H1U9|F5H1U9_HUMAN" 2 1319.6946 1.51 62660 10285 3 1319.698288 440.9055 Multiple PDZ domain protein OS=Homo sapiens OX=9606 GN=MPDZ PE=1 SV=2 6.41 2144 - 661091 - - - 2.7961 - 2.429 0.391 - 275.6 1 2 0 0.0037 13 0 0 0 1.74E+07 1.15E+07 - - - 5.3045 1 221125_WJC_METTL3_EV_vs_WT_F05.10286.10286.2 3.59E-08 13/24 A.FGNSTGGFDGQAR.Q sp|Q96PK6|RBM14_HUMAN 1 1312.5796 5.66 62661 10286 2 1312.583722 657.2971 RNA-binding protein 14 OS=Homo sapiens OX=9606 GN=RBM14 PE=1 SV=2 5.84 2144.1 - 460040 - - - 3.1198 - 2.648 0.636 - 571.4 1 1 0 0.0041 13 0 0 0 1.18E+07 2.08E+06 - - - 6.2365 0.9998 221125_WJC_METTL3_EV_vs_WT_F05.10287.10287.2 7.69E-07 20-Oct R.DEQQISAAVEK.A sp|Q6YN16|HSDL2_HUMAN 1 1216.5935 1.45 62662 10287 2 1216.594923 609.304 Hydroxysteroid dehydrogenase-like protein 2 OS=Homo sapiens OX=9606 GN=HSDL2 PE=1 SV=1 4.14 2144.3 - 425949 - - - 1.1318 - 2.218 0.519 - 428.6 1 2 0 0.0014 11 0 0 0 4.91E+07 3.38E+07 - - - 5.0289 0.8949 221125_WJC_METTL3_EV_vs_WT_F05.10288.10288.2 1.16E-07 20-Nov Y.VNFQQPADAER[166.11].A "sp|Q13310|PABP4_HUMAN,sp|P11940|PABP1_HUMAN,tr|A0A7I2V649|A0A7I2V649_HUMAN,tr|B1ANR0|B1ANR0_HUMAN,tr|A0A7I2V4L7|A0A7I2V4L7_HUMAN,tr|E5RHG7|E5RHG7_HUMAN,tr|B1ANR1|B1ANR1_HUMAN,tr|H0YAR2|H0YAR2_HUMAN,tr|E7ERJ7|E7ERJ7_HUMAN,tr|E5RJB9|E5RJB9_HUMAN,tr|A0A7I2YQ88|A0A7I2YQ88_HUMAN,tr|E5RH24|E5RH24_HUMAN,tr|H0YBN4|H0YBN4_HUMAN,tr|E5RGH3|E5RGH3_HUMAN,tr|A0A087WTT1|A0A087WTT1_HUMAN,tr|A0A7I2YQ90|A0A7I2YQ90_HUMAN,tr|E7EQV3|E7EQV3_HUMAN" 17 1283.6134 1.86 62663 10288 2 1283.620137 642.814 Polyadenylate-binding protein 4 OS=Homo sapiens OX=9606 GN=PABPC4 PE=1 SV=1 4.37 2144.4 - 377466 - - - 5.2609 - 2.43 0.577 - 434.5 1 1 0 0.0068 11 0 0 0 1.09E+07 5.85E+06 - - - 5.7026 0.9957 221125_WJC_METTL3_EV_vs_WT_F05.10290.10290.3 0.0221 Oct-48 K.YIASTQR[166.11]PDGTWR[166.11].K sp|Q9BRP8|PYM1_HUMAN 1 1569.7803 0.56 62665 10290 3 1569.782544 524.2674 Partner of Y14 and mago OS=Homo sapiens OX=9606 GN=PYM1 PE=1 SV=1 8.75 2144.7 - 320792 - - - 1.4422 - 1.497 0.261 - 100.8 1 2 0 0.0023 13 0 0 0 5.64E+06 1.01E+07 - - - 2.5432 0.9996 221125_WJC_METTL3_EV_vs_WT_F05.10296.10296.3 0.000466 Dec-40 K.MLPEIDQNK[136.11]DR[166.11].M "sp|P78344|IF4G2_HUMAN,tr|H0Y3P2|H0Y3P2_HUMAN,tr|D3DQV9|D3DQV9_HUMAN" 3 1375.6885 2.67 62670 10296 3 1375.688766 459.5701 Eukaryotic translation initiation factor 4 gamma 2 OS=Homo sapiens OX=9606 GN=EIF4G2 PE=1 SV=1 4.56 2145.5 - 1.23E+06 - - - 0.2152 - 2.409 0.384 - 219.5 1 2 1 0.0003 11 0 0 0 5.86E+07 2.20E+07 - - - 5.3188 0.9992 221125_WJC_METTL3_EV_vs_WT_F05.10298.10298.3 0.0858 Oct-40 K.GLSQSALPYRR.S "sp|P62277|RS13_HUMAN,tr|J3KMX5|J3KMX5_HUMAN,tr|E9PS50|E9PS50_HUMAN" 3 1246.6782 0.86 62671 10298 3 1246.679205 416.5667 40S ribosomal protein S13 OS=Homo sapiens OX=9606 GN=RPS13 PE=1 SV=2 10.84 2145.7 - 5.38E+06 - - - 0.7909 - 1.816 0.294 - 145.5 1 2 0 0.001 11 0 0 0 5.61E+07 6.50E+07 - - - 3.5125 0.9999 221125_WJC_METTL3_EV_vs_WT_F05.10299.10299.3 0.0219 Oct-36 K.K[136.11]PGDLSDELR[166.11].L "sp|Q13435|SF3B2_HUMAN,tr|E9PPJ0|E9PPJ0_HUMAN,tr|H0YEX5|H0YEX5_HUMAN" 3 1146.6 0.001 62672 10299 3 1146.600646 383.2073 Splicing factor 3B subunit 2 OS=Homo sapiens OX=9606 GN=SF3B2 PE=1 SV=2 4.56 2145.8 - 3.90E+06 - - - 0.5878 - 1.988 0.399 - 180.5 1 2 0 0.0007 10 0 0 0 0.00E+00 6.45E+07 - - - 4.995 0.9999 221125_WJC_METTL3_EV_vs_WT_F05.10300.10300.3 8.60E-06 Nov-40 K.DFQSGQHVIVR[166.11].T "sp|P46459|NSF_HUMAN,tr|I3L4Q9|I3L4Q9_HUMAN,tr|I3L338|I3L338_HUMAN,tr|I3L0L3|I3L0L3_HUMAN,tr|I3L0N3|I3L0N3_HUMAN" 5 1294.6658 1.45 62673 10300 3 1294.668227 432.5625 Vesicle-fusing ATPase OS=Homo sapiens OX=9606 GN=NSF PE=1 SV=3 6.74 2145.8 - 2.07E+06 - - - 1.9101 - 2.223 0.516 - 180.5 1 2 0 0.0025 11 0 0 0 2.05E+07 1.41E+07 - - - 6.5616 0.9575 221125_WJC_METTL3_EV_vs_WT_F05.10301.10301.3 0.00948 Oct-40 K.GVVEVTHDLQK[136.11].H "sp|P50454|SERPH_HUMAN,tr|E9PKH2|E9PKH2_HUMAN,tr|E9PJH8|E9PJH8_HUMAN" 3 1231.6652 1.68 62674 10301 3 1231.670454 411.5623 Serpin H1 OS=Homo sapiens OX=9606 GN=SERPINH1 PE=1 SV=2 5.32 2145.9 - 911626 - - - 4.265 - 1.671 0.206 - 96 1 2 0 0.0053 11 0 0 0 2.04E+08 1.21E+08 - - - 2.2938 0.9999 221125_WJC_METTL3_EV_vs_WT_F05.10302.10302.3 2.85E-05 13/44 R.VAEELALEQAKK.E "sp|Q9NX63|MIC19_HUMAN,tr|A0A286YEX5|A0A286YEX5_HUMAN,tr|F8WAR4|F8WAR4_HUMAN,tr|C9JRZ6|C9JRZ6_HUMAN" 4 1327.7347 2.16 62675 10302 3 1327.736436 443.5855 MICOS complex subunit MIC19 OS=Homo sapiens OX=9606 GN=CHCHD3 PE=1 SV=1 4.79 2146 - 802792 - - - 1.2841 - 2.49 0.455 - 262.7 1 2 0 0.0017 12 0 0 0 9.02E+07 4.18E+07 - - - 6.141 0.8256 221125_WJC_METTL3_EV_vs_WT_F05.10303.10303.3 0.0112 Aug-36 K.GKDMVVDIQR.R sp|Q9Y266|NUDC_HUMAN 1 1159.6019 0.48 62676 10303 3 1159.603525 387.5413 Nuclear migration protein nudC OS=Homo sapiens OX=9606 GN=NUDC PE=1 SV=1 5.96 2146.1 - 713683 - - - 1.3643 - 1.773 0.079 - 92 1 2 1 0.0016 10 0 0 0 8.41E+06 1.75E+07 - - - 1.0928 0.9998 221125_WJC_METTL3_EV_vs_WT_F05.10304.10304.3 0.00223 Nov-44 R.VAEELALEQAK[136.11]K[136.11].E "sp|Q9NX63|MIC19_HUMAN,tr|A0A286YEX5|A0A286YEX5_HUMAN,tr|F8WAR4|F8WAR4_HUMAN,tr|C9JRZ6|C9JRZ6_HUMAN" 4 1343.7631 2.15 62677 10304 3 1343.763958 448.9283 MICOS complex subunit MIC19 OS=Homo sapiens OX=9606 GN=CHCHD3 PE=1 SV=1 4.79 2146.2 - 620142 - - - 0.6154 - 2.338 0.338 - 213.5 1 2 0 0.0008 12 0 0 0 8.99E+07 4.18E+07 - - - 4.6623 0.9987 221125_WJC_METTL3_EV_vs_WT_F05.10306.10306.2 8.94E-05 14/20 K.GVVEVTHDLQK[136.11].H "sp|P50454|SERPH_HUMAN,tr|E9PKH2|E9PKH2_HUMAN,tr|E9PJH8|E9PJH8_HUMAN" 3 1231.6652 1.49 62679 10306 2 1231.670664 616.8399 Serpin H1 OS=Homo sapiens OX=9606 GN=SERPINH1 PE=1 SV=2 5.32 2146.4 - 280523 - - - 4.4355 - 2.77 0.477 - 788.4 1 2 0 0.0055 11 0 0 0 5.81E+07 3.90E+07 - - - 5.3186 0.9915 221125_WJC_METTL3_EV_vs_WT_F05.10307.10307.2 0.00561 20-Jul K.MLPEIDQNKDR.M "sp|P78344|IF4G2_HUMAN,tr|H0Y3P2|H0Y3P2_HUMAN,tr|D3DQV9|D3DQV9_HUMAN" 3 1357.666 11.05 62680 10307 2 1357.66698 679.8403 Eukaryotic translation initiation factor 4 gamma 2 OS=Homo sapiens OX=9606 GN=EIF4G2 PE=1 SV=1 4.56 2146.6 - 280134 - - - 0.7218 - 1.401 0.381 - 140.1 1 2 1 0.001 11 0 0 0 5.89E+06 5.33E+05 - - - 2.7669 0.9989 221125_WJC_METTL3_EV_vs_WT_F05.10309.10309.2 0.0189 24-Jul K.AMGQGLPDEEQEK[136.11].L "sp|Q9Y4W2|LAS1L_HUMAN,tr|A0A7I2V3Q3|A0A7I2V3Q3_HUMAN,tr|A0A7I2V4E5|A0A7I2V4E5_HUMAN" 3 1438.649 1.26 62682 10309 2 1438.648198 720.3318 Ribosomal biogenesis protein LAS1L OS=Homo sapiens OX=9606 GN=LAS1L PE=1 SV=2 4 2146.8 - 223648 - - - -0.529 - 1.454 0.308 - 117.4 1 2 0 -0.0008 13 0 0 0 2.83E+06 2.25E+06 - - - 2.2763 0.9998 221125_WJC_METTL3_EV_vs_WT_F05.10312.10312.2 7.87E-06 20-Nov R.DEQQISAAVEK[136.11].A sp|Q6YN16|HSDL2_HUMAN 1 1224.6077 1.45 62684 10312 2 1224.608783 613.3111 Hydroxysteroid dehydrogenase-like protein 2 OS=Homo sapiens OX=9606 GN=HSDL2 PE=1 SV=1 4.14 2147.2 - 1.15E+06 - - - 0.8468 - 2.344 0.47 - 528.7 1 2 0 0.001 11 0 0 0 4.91E+07 3.38E+07 - - - 4.8166 0.9705 221125_WJC_METTL3_EV_vs_WT_F05.10314.10314.3 0.266 Aug-32 R.KEDMEYALR.K "sp|Q13242|SRSF9_HUMAN,tr|H0YIB4|H0YIB4_HUMAN" 2 1153.5438 1.54 62685 10314 3 1153.544373 385.5219 Serine\arginine-rich splicing factor 9 OS=Homo sapiens OX=9606 GN=SRSF9 PE=1 SV=1 4.68 2147.4 - 3.68E+06 - - - 0.5323 - 1.236 0.178 - 93.5 1 2 0 0.0006 9 0 0 0 2.20E+07 1.43E+07 - - - 1.1629 0.9873 221125_WJC_METTL3_EV_vs_WT_F05.10315.10315.2 0.00454 13/18 L.C[160.03]GAIHSSIAK[136.11].Q sp|P36542|ATPG_HUMAN 1 1050.5372 1.12 62686 10315 2 1050.53939 526.2759 "ATP synthase subunit gamma, mitochondrial OS=Homo sapiens OX=9606 GN=ATP5F1C PE=1 SV=1" 8.23 2147.5 - 470510 - - - 2.1189 - 2.987 0.474 - 700.4 1 1 0 0.0022 10 0 0 0 7.46E+06 6.66E+06 - - - 5.5957 0.9998 221125_WJC_METTL3_EV_vs_WT_F05.10316.10316.2 2.36E-05 13/18 K.KPGDLSDELR.L "sp|Q13435|SF3B2_HUMAN,tr|E9PPJ0|E9PPJ0_HUMAN,tr|H0YEX5|H0YEX5_HUMAN" 3 1128.5775 1.39 62687 10316 2 1128.5795 565.296 Splicing factor 3B subunit 2 OS=Homo sapiens OX=9606 GN=SF3B2 PE=1 SV=2 4.56 2147.6 - 1.85E+06 - - - 1.7704 - 2.447 0.49 - 574 1 2 0 0.002 10 0 0 0 2.30E+07 1.66E+07 - - - 5.1573 0.9992 221125_WJC_METTL3_EV_vs_WT_F05.10318.10318.3 0.0267 Sep-44 R.LSAVC[160.03]IADREEK.G "sp|Q8IX18|DHX40_HUMAN,tr|J3KS08|J3KS08_HUMAN,tr|J3KSX9|J3KSX9_HUMAN" 3 1389.6922 1.59 62689 10318 3 1389.692772 464.238 Probable ATP-dependent RNA helicase DHX40 OS=Homo sapiens OX=9606 GN=DHX40 PE=1 SV=2 4.68 2147.8 - 269739 - - - 0.4008 - 2.232 0.349 - 121.9 1 2 1 0.0006 12 0 0 0 5.72E+06 3.60E+06 - - - 4.6564 0.9994 221125_WJC_METTL3_EV_vs_WT_F05.10319.10319.2 0.0453 24-Dec K.TDSITTGTVSTVK[136.11].N sp|Q86V15|CASZ1_HUMAN 1 1316.6915 1.93 62690 10319 2 1316.694804 659.353 Zinc finger protein castor homolog 1 OS=Homo sapiens OX=9606 GN=CASZ1 PE=1 SV=4 5.5 2148 - 226794 - - - 2.5275 - 2.362 0.405 - 485.6 1 2 0 0.0033 13 0 0 0 5.99E+06 3.11E+06 - - - 4.2372 1 221125_WJC_METTL3_EV_vs_WT_F05.10320.10320.2 7.52E-08 16/32 R.ATGGGLSSVGGGSSTIK.Y sp|P04259|K2C6B_HUMAN 1 1434.7314 999 62691 10320 2 1434.731593 718.373 "Keratin, type II cytoskeletal 6B OS=Homo sapiens OX=9606 GN=KRT6B PE=1 SV=5" 8.8 2148.1 - 212330 - - - 0.1087 - 3.062 0.603 - 659.3 1 2 0 0.0002 17 0 0 0 3.59E+08 0.00E+00 - - - 6.246 0.9978 221125_WJC_METTL3_EV_vs_WT_F05.10321.10321.2 3.15E-05 22-Oct R.VAEELALEQAK[136.11]K[136.11].E "sp|Q9NX63|MIC19_HUMAN,tr|A0A286YEX5|A0A286YEX5_HUMAN,tr|F8WAR4|F8WAR4_HUMAN,tr|C9JRZ6|C9JRZ6_HUMAN" 4 1343.7631 2.34 62692 10321 2 1343.770207 672.8888 MICOS complex subunit MIC19 OS=Homo sapiens OX=9606 GN=CHCHD3 PE=1 SV=1 4.79 2148.2 - 176848 - - - 5.2658 - 2.432 0.551 - 278.3 1 2 0 0.0071 12 0 0 0 1.05E+07 4.49E+06 - - - 5.4468 0.9994 221125_WJC_METTL3_EV_vs_WT_F05.10322.10322.2 0.00576 18-Jul K.DDYGFSGSQK.L "sp|Q9H4A3|WNK1_HUMAN,tr|F5GWT4|F5GWT4_HUMAN,tr|A0A6Q8PFM0|A0A6Q8PFM0_HUMAN,tr|H0YH68|H0YH68_HUMAN" 4 1102.4567 1.91 62693 10322 2 1102.457751 552.2356 Serine\threonine-protein kinase WNK1 OS=Homo sapiens OX=9606 GN=WNK1 PE=1 SV=2 4.21 2148.4 - 134353 - - - 0.937 - 1.434 0.413 - 108.2 1 2 0 0.001 10 0 0 0 4.01E+06 2.09E+06 - - - 3.0973 0.9996 221125_WJC_METTL3_EV_vs_WT_F05.10323.10323.2 0.000999 26-Aug R.QVAASPAVGQPLQK.E "sp|Q92547|TOPB1_HUMAN,tr|A0A2R8YD63|A0A2R8YD63_HUMAN" 2 1392.7725 1.48 62694 10323 2 1392.772883 697.3935 DNA topoisomerase 2-binding protein 1 OS=Homo sapiens OX=9606 GN=TOPBP1 PE=1 SV=3 8.75 2148.5 - 106951 - - - 0.2649 - 1.693 0.401 - 158.2 1 2 0 0.0004 14 0 0 0 5.22E+06 3.53E+06 - - - 3.3239 0.9989 221125_WJC_METTL3_EV_vs_WT_F05.10325.10325.2 0.00659 May-36 R.EAAAYSSGGGAAGAGLAGR[166.11].E "sp|P43694|GATA4_HUMAN,tr|A0A087WZ09|A0A087WZ09_HUMAN" 2 1602.7626 2.39 62696 10325 2 1602.76132 802.3886 Transcription factor GATA-4 OS=Homo sapiens OX=9606 GN=GATA4 PE=1 SV=2 6.1 2148.8 - 105088 - - - -0.778 - 1.238 0.379 - 46.9 1 2 0 -0.0012 19 0 0 0 1.15E+07 4.81E+06 - - - 2.3648 0.9999 221125_WJC_METTL3_EV_vs_WT_F05.10328.10328.3 0.00148 Dec-40 K.GVVEVTHDLQK.H "sp|P50454|SERPH_HUMAN,tr|E9PKH2|E9PKH2_HUMAN,tr|E9PJH8|E9PJH8_HUMAN" 3 1223.651 1.68 62697 10328 3 1223.651733 408.8909 Serpin H1 OS=Homo sapiens OX=9606 GN=SERPINH1 PE=1 SV=2 5.32 2149.2 - 1.11E+07 - - - 0.5982 - 2.441 0.366 - 132.2 1 2 0 0.0007 11 0 0 0 2.02E+08 1.20E+08 - - - 5.1555 0.9999 221125_WJC_METTL3_EV_vs_WT_F05.10329.10329.2 1.47E-05 15/20 K.GVVEVTHDLQK.H "sp|P50454|SERPH_HUMAN,tr|E9PKH2|E9PKH2_HUMAN,tr|E9PJH8|E9PJH8_HUMAN" 3 1223.651 1.49 62698 10329 2 1223.652431 612.8328 Serpin H1 OS=Homo sapiens OX=9606 GN=SERPINH1 PE=1 SV=2 5.32 2149.2 - 2.73E+06 - - - 1.1686 - 2.919 0.499 - 806.8 1 2 0 0.0014 11 0 0 0 5.80E+07 3.90E+07 - - - 5.6241 0.9969 221125_WJC_METTL3_EV_vs_WT_F05.10332.10332.3 0.0057 Oct-40 R.ELNNYEIR[166.11]PGR[166.11].L "sp|A0AV96|RBM47_HUMAN,tr|D6RBS9|D6RBS9_HUMAN,tr|B7Z8Z7|B7Z8Z7_HUMAN,tr|D6R9M7|D6R9M7_HUMAN,tr|D6REZ6|D6REZ6_HUMAN,tr|D6R9D6|D6R9D6_HUMAN" 6 1379.7061 1.76 62701 10332 3 1379.708287 460.9093 RNA-binding protein 47 OS=Homo sapiens OX=9606 GN=RBM47 PE=1 SV=2 6.24 2149.4 - 853775 - - - 1.6199 - 1.753 0.241 - 182.8 1 2 0 0.0022 11 0 0 0 4.61E+07 2.62E+07 - - - 2.8209 0.9921 221125_WJC_METTL3_EV_vs_WT_F05.10333.10333.2 8.87E-07 20-Dec Y.VNFQQPADAER.A "sp|Q13310|PABP4_HUMAN,sp|P11940|PABP1_HUMAN,tr|A0A7I2V649|A0A7I2V649_HUMAN,tr|B1ANR0|B1ANR0_HUMAN,tr|A0A7I2V4L7|A0A7I2V4L7_HUMAN,tr|E5RHG7|E5RHG7_HUMAN,tr|B1ANR1|B1ANR1_HUMAN,tr|H0YAR2|H0YAR2_HUMAN,tr|E7ERJ7|E7ERJ7_HUMAN,tr|E5RJB9|E5RJB9_HUMAN,tr|A0A7I2YQ88|A0A7I2YQ88_HUMAN,tr|E5RH24|E5RH24_HUMAN,tr|H0YBN4|H0YBN4_HUMAN,tr|E5RGH3|E5RGH3_HUMAN,tr|A0A087WTT1|A0A087WTT1_HUMAN,tr|A0A7I2YQ90|A0A7I2YQ90_HUMAN,tr|E7EQV3|E7EQV3_HUMAN" 17 1273.6051 1.87 62702 10333 2 1273.603484 637.8098 Polyadenylate-binding protein 4 OS=Homo sapiens OX=9606 GN=PABPC4 PE=1 SV=1 4.37 2149.5 - 548248 - - - -1.2798 - 2.451 0.52 - 549 1 1 0 -0.0016 11 0 0 0 1.10E+07 5.85E+06 - - - 5.3064 0.9923 221125_WJC_METTL3_EV_vs_WT_F05.10334.10334.3 0.0676 Aug-48 K.YIASTQRPDGTWR.K sp|Q9BRP8|PYM1_HUMAN 1 1549.7637 0.46 62703 10334 3 1549.766336 517.5952 Partner of Y14 and mago OS=Homo sapiens OX=9606 GN=PYM1 PE=1 SV=1 8.75 2149.7 - 538891 - - - 1.6751 - 1.435 0.245 - 67.1 1 2 0 0.0026 13 0 0 0 5.70E+06 1.24E+07 - - - 2.25 0.9976 221125_WJC_METTL3_EV_vs_WT_F05.10336.10336.3 0.00194 Oct-40 R.VLSEKDVDPVR.T "sp|P24928|RPB1_HUMAN,tr|A0A6Q8PGB0|A0A6Q8PGB0_HUMAN" 2 1255.6772 1.31 62705 10336 3 1255.677576 419.5663 DNA-directed RNA polymerase II subunit RPB1 OS=Homo sapiens OX=9606 GN=POLR2A PE=1 SV=2 4.56 2149.9 - 477692 - - - 0.2867 - 2.042 0.289 - 108.9 1 2 1 0.0004 11 0 0 0 4.00E+06 3.06E+06 - - - 3.7901 0.9996 221125_WJC_METTL3_EV_vs_WT_F05.10337.10337.3 0.000365 13/44 R.LSAVC[160.03]IADR[166.11]EEK[136.11].G "sp|Q8IX18|DHX40_HUMAN,tr|J3KS08|J3KS08_HUMAN,tr|J3KSX9|J3KSX9_HUMAN" 3 1407.7147 2.37 62706 10337 3 1407.715971 470.2455 Probable ATP-dependent RNA helicase DHX40 OS=Homo sapiens OX=9606 GN=DHX40 PE=1 SV=2 4.68 2150 - 413905 - - - 0.9135 - 2.725 0.372 - 363.4 1 2 1 0.0013 12 0 0 0 8.95E+06 3.77E+06 - - - 5.4658 0.9998 221125_WJC_METTL3_EV_vs_WT_F05.10340.10340.2 0.000198 16-Oct R.KEDMEYALR.K "sp|Q13242|SRSF9_HUMAN,tr|H0YIB4|H0YIB4_HUMAN" 2 1153.5438 4.81 62707 10340 2 1153.545181 577.7792 Serine\arginine-rich splicing factor 9 OS=Homo sapiens OX=9606 GN=SRSF9 PE=1 SV=1 4.68 2150.5 - 762388 - - - 1.2327 - 2.104 0.493 - 390.7 1 2 0 0.0014 9 0 0 0 2.29E+07 4.76E+06 - - - 4.8338 0.9991 221125_WJC_METTL3_EV_vs_WT_F05.10343.10343.3 0.00931 Aug-48 K.VYSSHTGYPGGFR[166.11].Q "sp|Q9BYD1|RM13_HUMAN,tr|E5RJI7|E5RJI7_HUMAN" 2 1436.6712 1.2 62710 10343 3 1436.672477 479.8977 "39S ribosomal protein L13, mitochondrial OS=Homo sapiens OX=9606 GN=MRPL13 PE=1 SV=1" 8.57 2150.9 - 763723 - - - 0.8659 - 1.771 0.301 - 61.1 1 2 0 0.0012 13 0 0 0 1.54E+07 1.28E+07 - - - 3.4451 1 221125_WJC_METTL3_EV_vs_WT_F05.10344.10344.2 6.86E-06 15/22 R.VAEELALEQAKK.E "sp|Q9NX63|MIC19_HUMAN,tr|A0A286YEX5|A0A286YEX5_HUMAN,tr|F8WAR4|F8WAR4_HUMAN,tr|C9JRZ6|C9JRZ6_HUMAN" 4 1327.7347 2.34 62711 10344 2 1327.736057 664.8746 MICOS complex subunit MIC19 OS=Homo sapiens OX=9606 GN=CHCHD3 PE=1 SV=1 4.79 2151 - 724470 - - - 0.9987 - 3.167 0.513 - 923.5 1 2 0 0.0013 12 0 0 0 1.05E+07 4.49E+06 - - - 5.8628 0.9987 221125_WJC_METTL3_EV_vs_WT_F05.10345.10345.2 0.0113 18-Jul R.GLDNTEFQGK.R "sp|Q9BWF3|RBM4_HUMAN,sp|Q9BQ04|RBM4B_HUMAN,tr|E9PB51|E9PB51_HUMAN" 3 1107.5197 1.32 62712 10345 2 1107.521192 554.7671 RNA-binding protein 4 OS=Homo sapiens OX=9606 GN=RBM4 PE=1 SV=1 4.37 2151.1 - 713467 - - - 1.3896 - 1.515 0.316 - 110.1 1 2 0 0.0015 10 0 0 0 3.99E+07 3.02E+07 - - - 2.534 0.9997 221125_WJC_METTL3_EV_vs_WT_F05.10347.10347.2 0.016 18-Nov K.SNLNQVVQER[166.11].N "sp|Q9UPS8|ANR26_HUMAN,tr|A0A6Q8PFU2|A0A6Q8PFU2_HUMAN,tr|E7ESJ3|E7ESJ3_HUMAN" 3 1195.6185 2.32 62714 10347 2 1195.619869 598.8165 Ankyrin repeat domain-containing protein 26 OS=Homo sapiens OX=9606 GN=ANKRD26 PE=1 SV=4 5.72 2151.4 - 263426 - - - 1.1709 - 2.333 0.332 - 603 1 2 0 0.0014 10 0 0 0 1.47E+07 6.36E+06 - - - 3.8574 0.9858 221125_WJC_METTL3_EV_vs_WT_F05.10351.10351.3 4.44E-07 Dec-40 T.YSC[160.03]VGVFQHGK[136.11].V "sp|P54652|HSP72_HUMAN,sp|P0DMV8|HS71A_HUMAN,sp|P34931|HS71L_HUMAN,sp|P11142|HSP7C_HUMAN,sp|P0DMV9|HS71B_HUMAN,tr|E9PQQ4|E9PQQ4_HUMAN,tr|E9PNE6|E9PNE6_HUMAN,tr|E9PKE3|E9PKE3_HUMAN,tr|E9PLF4|E9PLF4_HUMAN,tr|Q53FA3|Q53FA3_HUMAN,tr|E9PI65|E9PI65_HUMAN,tr|V9GZ37|V9GZ37_HUMAN,tr|E9PK54|E9PK54_HUMAN,tr|E9PN25|E9PN25_HUMAN,tr|E9PPY6|E9PPY6_HUMAN,tr|E9PQK7|E9PQK7_HUMAN,tr|A0A0G2JIW1|A0A0G2JIW1_HUMAN" 17 1288.6114 0.12 62716 10351 3 1288.611391 430.5444 Heat shock-related 70 kDa protein 2 OS=Homo sapiens OX=9606 GN=HSPA2 PE=1 SV=1 8.21 2151.8 - 1.12E+06 - - - -0.0008 - 1.878 0.41 - 138.9 1 1 0 0 11 0 0 0 8.14E+06 6.95E+07 - - - 4.9014 0.9996 221125_WJC_METTL3_EV_vs_WT_F05.10352.10352.2 0.000224 18-Nov R.SGYSEVNLSK[136.11].L "sp|P09884|DPOLA_HUMAN,tr|A6NMQ1|A6NMQ1_HUMAN" 2 1090.5386 0.17 62717 10352 2 1090.540908 546.2766 DNA polymerase alpha catalytic subunit OS=Homo sapiens OX=9606 GN=POLA1 PE=1 SV=2 5.72 2151.9 - 699714 - - - 2.1127 - 1.89 0.499 - 267.9 1 2 0 0.0023 10 0 0 0 1.67E+06 9.88E+06 - - - 4.5028 0.9997 221125_WJC_METTL3_EV_vs_WT_F05.10354.10354.2 1.22E-05 16-Oct R.SHGFAAEFK[136.11].L "sp|P55265|DSRAD_HUMAN,tr|A0A3B3IRQ9|A0A3B3IRQ9_HUMAN,tr|A0A3B3ISU1|A0A3B3ISU1_HUMAN,tr|A0A7P0Z4K3|A0A7P0Z4K3_HUMAN,tr|A0A3B3ISX1|A0A3B3ISX1_HUMAN,tr|A0A7P0Z4F9|A0A7P0Z4F9_HUMAN" 6 1000.4858 0.63 62719 10354 2 1000.486471 501.2502 Double-stranded RNA-specific adenosine deaminase OS=Homo sapiens OX=9606 GN=ADAR PE=1 SV=4 6.47 2152.1 - 678576 - - - 0.6907 - 2.206 0.335 - 496.2 1 2 0 0.0007 9 0 0 0 1.12E+07 1.78E+07 - - - 3.804 0.9417 221125_WJC_METTL3_EV_vs_WT_F05.10355.10355.3 0.436 Aug-40 K.EKLEAEMEAAR.H sp|Q8WXF1|PSPC1_HUMAN 1 1275.6129 1.2 62720 10355 3 1275.613022 426.2116 Paraspeckle component 1 OS=Homo sapiens OX=9606 GN=PSPC1 PE=1 SV=1 4.49 2152.2 - 603408 - - - 0.0949 - 1.351 0.201 - 108.1 1 2 1 0.0001 11 0 0 0 7.82E+06 6.51E+06 - - - 1.6356 0.9996 221125_WJC_METTL3_EV_vs_WT_F05.10356.10356.2 0.000459 18-Sep K.SNLNQVVQER.N "sp|Q9UPS8|ANR26_HUMAN,tr|A0A6Q8PFU2|A0A6Q8PFU2_HUMAN,tr|E7ESJ3|E7ESJ3_HUMAN" 3 1185.6102 2.32 62721 10356 2 1185.612239 593.8124 Ankyrin repeat domain-containing protein 26 OS=Homo sapiens OX=9606 GN=ANKRD26 PE=1 SV=4 5.72 2152.3 - 502601 - - - 1.7206 - 1.94 0.416 - 313.7 1 2 0 0.002 10 0 0 0 1.47E+07 6.36E+06 - - - 3.9627 0.9998 221125_WJC_METTL3_EV_vs_WT_F05.10361.10361.3 0.0291 Nov-48 R.GLPPHTTDQDLVK.L "sp|P29558|RBMS1_HUMAN,tr|E7ETU5|E7ETU5_HUMAN,tr|F6Y5H0|F6Y5H0_HUMAN,tr|E7EPF2|E7EPF2_HUMAN" 4 1419.7358 2.24 62725 10361 3 1419.736856 474.2525 "RNA-binding motif, single-stranded-interacting protein 1 OS=Homo sapiens OX=9606 GN=RBMS1 PE=1 SV=3" 5.21 2152.9 - 676474 - - - 0.748 - 2.018 0.391 - 116 1 2 0 0.0011 13 0 0 0 1.29E+07 5.75E+06 - - - 4.8026 0.9984 221125_WJC_METTL3_EV_vs_WT_F05.10362.10362.2 0.015 12-Jun R.SNWQNYR.Q "sp|Q9Y2W1|TR150_HUMAN,tr|A0A3B3ITZ9|A0A3B3ITZ9_HUMAN" 2 966.4308 8.41 62726 10362 2 966.430343 484.2227 Thyroid hormone receptor-associated protein 3 OS=Homo sapiens OX=9606 GN=THRAP3 PE=1 SV=2 8.46 2153.1 - 485862 - - - -0.4501 - 1.337 0.273 - 199.1 1 2 0 -0.0004 7 0 0 0 2.01E+07 2.39E+06 - - - 1.9775 0.9994 221125_WJC_METTL3_EV_vs_WT_F05.10367.10367.2 0.000972 28-Sep R.FSTVAGESGSADTVR.D sp|P04040|CATA_HUMAN 1 1482.6951 999 62731 10367 2 1482.697519 742.3548 Catalase OS=Homo sapiens OX=9606 GN=CAT PE=1 SV=3 4.37 2153.4 - 148849 - - - 1.6645 - 1.534 0.456 - 175.4 1 2 0 0.0025 15 0 0 0 1.46E+07 0.00E+00 - - - 3.4602 0.9981 221125_WJC_METTL3_EV_vs_WT_F05.10368.10368.2 1.51E-05 26-Jul K.YSPTSPTYSPTSPK.Y "sp|P24928|RPB1_HUMAN,tr|A0A6Q8PGB0|A0A6Q8PGB0_HUMAN" 2 1511.7144 0.64 62732 10368 2 1511.720913 756.8645 DNA-directed RNA polymerase II subunit RPB1 OS=Homo sapiens OX=9606 GN=POLR2A PE=1 SV=2 8.5 2153.6 - 120687 - - - 4.315 - 1.729 0.542 - 87 1 2 0 0.0065 14 0 0 0 1.26E+06 1.97E+06 - - - 4.4162 0.9994 221125_WJC_METTL3_EV_vs_WT_F05.10372.10372.3 0.000104 Nov-40 R.YR[166.11]DPTTVTTLR[166.11].V "sp|P63151|2ABA_HUMAN,tr|A0A590UJY3|A0A590UJY3_HUMAN" 2 1341.7156 0.49 62734 10372 3 1341.715756 448.2458 Serine\threonine-protein phosphatase 2A 55 kDa regulatory subunit B alpha isoform OS=Homo sapiens OX=9606 GN=PPP2R2A PE=1 SV=1 8.75 2154 - 2.85E+06 - - - 0.1506 - 2.247 0.371 - 222.7 1 2 1 0.0002 11 0 0 0 4.81E+07 9.77E+07 - - - 4.9762 0.9786 221125_WJC_METTL3_EV_vs_WT_F05.10373.10373.2 0.000278 16-Sep Y.PDGIISK[136.11]PK[136.11].N sp|Q86U44|MTA70_HUMAN 1 969.583 0.001 62735 10373 2 969.58228 485.7988 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 9.01 2154.1 - 777099 - - - -0.724 - 1.774 0.372 - 216.9 1 1 0 -0.0007 9 0 0 0 0.00E+00 2.74E+07 - - - 3.4468 0.9998 221125_WJC_METTL3_EV_vs_WT_F05.10374.10374.2 0.0141 20-Oct R.NLQEIQQAGER.L "sp|Q8N1F7|NUP93_HUMAN,tr|H3BM93|H3BM93_HUMAN,tr|H3BV11|H3BV11_HUMAN,tr|H3BRI8|H3BRI8_HUMAN,tr|H3BVG0|H3BVG0_HUMAN" 5 1284.6422 2.2 62736 10374 2 1284.642824 643.3284 Nuclear pore complex protein Nup93 OS=Homo sapiens OX=9606 GN=NUP93 PE=1 SV=2 4.53 2154.2 - 767979 - - - 0.4639 - 2.137 0.406 - 385 1 2 0 0.0006 11 0 0 0 8.70E+07 3.96E+07 - - - 4.0939 0.9997 221125_WJC_METTL3_EV_vs_WT_F05.10376.10376.2 0.0576 16-Nov R.RPSVYLPTR.E sp|Q9BW61|DDA1_HUMAN 1 1087.6138 1.24 62738 10376 2 1087.61357 544.8142 DET1- and DDB1-associated protein 1 OS=Homo sapiens OX=9606 GN=DDA1 PE=1 SV=1 10.84 2154.5 - 517798 - - - -0.2372 - 2.086 0.338 - 232.4 1 2 0 -0.0003 9 0 0 0 2.94E+07 2.37E+07 - - - 3.6645 0.9996 221125_WJC_METTL3_EV_vs_WT_F05.10378.10378.3 0.0226 Aug-32 K.FENLDMSHR[166.11].A "sp|Q96T37|RBM15_HUMAN,tr|A0A494C001|A0A494C001_HUMAN,tr|A0A499FJY3|A0A499FJY3_HUMAN,tr|A0A087WWP4|A0A087WWP4_HUMAN" 4 1157.5163 1.17 62740 10378 3 1157.515808 386.846 RNA-binding protein 15 OS=Homo sapiens OX=9606 GN=RBM15 PE=1 SV=2 5.32 2154.7 - 565915 - - - -0.4354 - 1.637 0.356 - 67.5 1 2 0 -0.0005 9 0 0 0 6.66E+06 5.68E+06 - - - 3.9943 0.9103 221125_WJC_METTL3_EV_vs_WT_F05.10379.10379.3 1.61 Sep-64 R.ATGGGLSSVGGGSSTIK.Y sp|P04259|K2C6B_HUMAN 1 1434.7314 165.65 62741 10379 3 1434.730776 479.2511 "Keratin, type II cytoskeletal 6B OS=Homo sapiens OX=9606 GN=KRT6B PE=1 SV=5" 8.8 2154.8 - 422434 - - - -0.4607 - 1.467 0.09 - 62.1 1 2 0 -0.0007 17 0 0 0 1.37E+07 8.27E+04 - - - 0.5114 0.9821 221125_WJC_METTL3_EV_vs_WT_F05.10380.10380.3 0.0766 Sep-36 K.VNELR[166.11]EELQR[166.11].R "sp|Q9BUJ2|HNRL1_HUMAN,tr|A0A087X1I2|A0A087X1I2_HUMAN,tr|M0R247|M0R247_HUMAN" 3 1304.6952 0.52 62742 10380 3 1304.697063 435.9057 Heterogeneous nuclear ribonucleoprotein U-like protein 1 OS=Homo sapiens OX=9606 GN=HNRNPUL1 PE=1 SV=2 4.79 2155 - 282552 - - - 1.4639 - 1.496 0.259 - 129.1 1 2 1 0.0019 10 0 0 0 9.14E+07 1.76E+08 - - - 2.6034 0.9997 221125_WJC_METTL3_EV_vs_WT_F05.10381.10381.2 0.000398 20-Dec K.TPVEPEVAIHR.L "sp|P60866|RS20_HUMAN,tr|E5RJX2|E5RJX2_HUMAN,tr|E5RIP1|E5RIP1_HUMAN,tr|A0A7P0S5H5|A0A7P0S5H5_HUMAN" 4 1246.667 1.44 62743 10381 2 1246.669174 624.3408 40S ribosomal protein S20 OS=Homo sapiens OX=9606 GN=RPS20 PE=1 SV=1 5.37 2155.1 - 263767 - - - 1.7551 - 2.413 0.42 - 529.7 1 2 0 0.0022 11 0 0 0 1.03E+08 7.14E+07 - - - 4.5254 1 221125_WJC_METTL3_EV_vs_WT_F05.10382.10382.2 1.65E-05 26-Dec M.FVETQASQGTLQTR[166.11].T sp|P78527|PRKDC_HUMAN 1 1574.7928 0.53 62744 10382 2 1574.792433 788.4037 DNA-dependent protein kinase catalytic subunit OS=Homo sapiens OX=9606 GN=PRKDC PE=1 SV=3 6 2155.2 - 94425.9 - - - -0.2362 - 2.604 0.628 - 408.3 1 1 0 -0.0004 14 0 0 0 1.32E+06 2.49E+06 - - - 6.081 0.9999 221125_WJC_METTL3_EV_vs_WT_F05.10384.10384.2 4.23E-05 13/18 R.YPDGIISK[136.11]PK[136.11].N sp|Q86U44|MTA70_HUMAN 1 1132.6463 0.02 62745 10384 2 1132.646659 567.3304 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 8.5 2155.5 - 1.66E+06 - - - 0.3081 - 2.108 0.563 - 629.7 1 2 0 0.0003 10 0 0 0 1.94E+06 9.53E+07 - - - 5.2808 0.9982 221125_WJC_METTL3_EV_vs_WT_F05.10386.10386.3 0.011 Oct-40 R.K[136.11]GTGLLSSDYR[166.11].L "sp|Q7Z2W4|ZCCHV_HUMAN,tr|C9J6P4|C9J6P4_HUMAN,tr|A0A7P0T8C6|A0A7P0T8C6_HUMAN" 3 1213.6422 0.11 62746 10386 3 1213.640508 405.5547 Zinc finger CCCH-type antiviral protein 1 OS=Homo sapiens OX=9606 GN=ZC3HAV1 PE=1 SV=3 8.59 2155.7 - 742200 - - - -1.3703 - 1.72 0.263 - 124.6 1 2 0 -0.0017 11 0 0 0 5.06E+06 4.50E+07 - - - 3.0124 0.9998 221125_WJC_METTL3_EV_vs_WT_F05.10388.10388.2 0.00699 18-Oct R.GLDNTEFQGK[136.11].R "sp|Q9BWF3|RBM4_HUMAN,sp|Q9BQ04|RBM4B_HUMAN,tr|E9PB51|E9PB51_HUMAN" 3 1115.5339 1.32 62748 10388 2 1115.53472 558.7742 RNA-binding protein 4 OS=Homo sapiens OX=9606 GN=RBM4 PE=1 SV=1 4.37 2155.9 - 1.96E+06 - - - 0.7772 - 1.988 0.456 - 265.4 1 2 0 0.0009 10 0 0 0 3.99E+07 3.02E+07 - - - 4.3267 0.9992 221125_WJC_METTL3_EV_vs_WT_F05.10389.10389.2 8.64E-06 18-Dec R.ASAVSELSPR.E "sp|Q9Y2W1|TR150_HUMAN,tr|A0A3B3ITZ9|A0A3B3ITZ9_HUMAN" 2 1015.5298 2.72 62749 10389 2 1015.531252 508.7722 Thyroid hormone receptor-associated protein 3 OS=Homo sapiens OX=9606 GN=THRAP3 PE=1 SV=2 6.05 2156.1 - 962048 - - - 1.4062 - 2.436 0.198 - 615.8 1 2 0 0.0014 10 0 0 0 9.58E+07 3.52E+07 - - - 2.9882 0.9998 221125_WJC_METTL3_EV_vs_WT_F05.10391.10391.2 0.00145 18-Nov K.K[136.11]VTLGDTLTR[166.11].R "sp|Q9UKV3|ACINU_HUMAN,tr|G3V3B0|G3V3B0_HUMAN,tr|S4R3H4|S4R3H4_HUMAN,tr|E7EQT4|E7EQT4_HUMAN" 4 1120.6571 1.39 62751 10391 2 1120.657424 561.3358 Apoptotic chromatin condensation inducer in the nucleus OS=Homo sapiens OX=9606 GN=ACIN1 PE=1 SV=2 8.75 2156.3 - 623387 - - - 0.2954 - 2.17 0.418 - 418.5 1 2 0 0.0003 10 0 0 0 3.32E+07 2.38E+07 - - - 4.2907 0.9997 221125_WJC_METTL3_EV_vs_WT_F05.10393.10393.2 0.000518 24-Dec R.SAPGAASAAAALK[136.11].Q sp|Q9H7S9|ZN703_HUMAN 1 1092.6019 1.49 62753 10393 2 1092.60319 547.3082 Zinc finger protein 703 OS=Homo sapiens OX=9606 GN=ZNF703 PE=1 SV=1 8.47 2156.5 - 336304 - - - 1.2054 - 1.982 0.418 - 494.8 1 2 0 0.0013 13 0 0 0 2.76E+07 1.85E+07 - - - 3.8837 0.9999 221125_WJC_METTL3_EV_vs_WT_F05.10398.10398.2 7.28E-05 13/24 R.SAPGAASAAAALK.Q sp|Q9H7S9|ZN703_HUMAN 1 1084.5877 1.51 62756 10398 2 1084.587432 543.3011 Zinc finger protein 703 OS=Homo sapiens OX=9606 GN=ZNF703 PE=1 SV=1 8.47 2157.2 - 1.08E+06 - - - -0.2222 - 2.163 0.517 - 498.1 1 2 0 -0.0002 13 0 0 0 2.76E+07 1.83E+07 - - - 4.8396 1 221125_WJC_METTL3_EV_vs_WT_F05.10400.10400.2 8.61E-05 24-Dec R.DTEMLATGAQDGK.L sp|Q2TAY7|SMU1_HUMAN 1 1335.5976 1.1 62758 10400 2 1335.597935 668.8061 WD40 repeat-containing protein SMU1 OS=Homo sapiens OX=9606 GN=SMU1 PE=1 SV=2 4.03 2157.4 - 776736 - - - 0.2171 - 2.651 0.573 - 612.6 1 2 0 0.0003 13 0 0 0 1.92E+07 1.73E+07 - - - 5.7753 0.9998 221125_WJC_METTL3_EV_vs_WT_F05.10406.10406.2 0.000119 22-Dec R.IQNAGGSVMIQR.V "sp|O75688|PPM1B_HUMAN,sp|P35813|PPM1A_HUMAN,tr|B8ZZF0|B8ZZF0_HUMAN,tr|A0A3B3IS24|A0A3B3IS24_HUMAN,tr|C9JIR6|C9JIR6_HUMAN,tr|E9PKB5|E9PKB5_HUMAN" 6 1272.6609 2.81 62762 10406 2 1272.661017 637.3377 Protein phosphatase 1B OS=Homo sapiens OX=9606 GN=PPM1B PE=1 SV=1 9.75 2158.2 - 719915 - - - 0.1273 - 2.617 0.351 - 484.4 1 2 0 0.0002 12 0 0 0 7.55E+07 2.69E+07 - - - 4.1647 0.9983 221125_WJC_METTL3_EV_vs_WT_F05.10408.10408.3 4.38E-05 Oct-36 K.VHQLYETIQR.W "sp|Q13561|DCTN2_HUMAN,tr|H0YI98|H0YI98_HUMAN,tr|A8K8J9|A8K8J9_HUMAN,tr|A0A7I2V4H4|A0A7I2V4H4_HUMAN,tr|A0A7I2V4Y9|A0A7I2V4Y9_HUMAN" 5 1285.6779 3.67 62764 10408 3 1285.679445 429.5666 Dynactin subunit 2 OS=Homo sapiens OX=9606 GN=DCTN2 PE=1 SV=4 6.72 2158.3 - 5.35E+06 - - - 1.2134 - 2.153 0.207 - 172.3 1 2 0 0.0016 10 0 0 0 1.31E+08 3.58E+07 - - - 3.087 1 221125_WJC_METTL3_EV_vs_WT_F05.10409.10409.3 1.88E-05 Dec-44 K.QDPSVLHTEEMR[166.11].F "sp|P50502|F10A1_HUMAN,sp|Q8NFI4|F10A5_HUMAN,tr|Q3KNR6|Q3KNR6_HUMAN,tr|F8WAQ7|F8WAQ7_HUMAN" 4 1450.675 1.05 62765 10409 3 1450.674825 484.5656 Hsc70-interacting protein OS=Homo sapiens OX=9606 GN=ST13 PE=1 SV=2 4.65 2158.4 - 1.02E+06 - - - -0.1193 - 2.482 0.473 - 231.6 1 2 0 -0.0002 12 0 0 0 3.11E+07 2.97E+07 - - - 6.3332 0.9999 221125_WJC_METTL3_EV_vs_WT_F05.10410.10410.2 0.00183 13/24 R.DTEMLATGAQDGK[136.11].L sp|Q2TAY7|SMU1_HUMAN 1 1343.6118 1.1 62766 10410 2 1343.611971 672.8132 WD40 repeat-containing protein SMU1 OS=Homo sapiens OX=9606 GN=SMU1 PE=1 SV=2 4.03 2158.6 - 919261 - - - 0.0938 - 2.584 0.465 - 522.4 1 2 0 0.0001 13 0 0 0 1.92E+07 1.73E+07 - - - 4.912 0.9989 221125_WJC_METTL3_EV_vs_WT_F05.10411.10411.3 0.813 Nov-36 R.EVVTEHLINK[136.11].V "sp|Q13618|CUL3_HUMAN,tr|H7C1L6|H7C1L6_HUMAN,tr|A0A087X1R9|A0A087X1R9_HUMAN" 3 1188.6594 2.3 62767 10411 3 1188.658495 397.2271 Cullin-3 OS=Homo sapiens OX=9606 GN=CUL3 PE=1 SV=2 5.4 2158.7 - 378963 - - - -0.7513 - 2.157 0.222 - 108.4 1 2 0 -0.0009 10 0 0 0 1.13E+07 4.91E+06 - - - 3.2598 1 221125_WJC_METTL3_EV_vs_WT_F05.10414.10414.2 9.30E-07 24-Nov R.LELSSSASPQEER[166.11].T "sp|Q9C0C7|AMRA1_HUMAN,tr|A0A075B6T1|A0A075B6T1_HUMAN" 2 1441.6924 0.62 62768 10414 2 1441.69219 721.8535 Activating molecule in BECN1-regulated autophagy protein 1 OS=Homo sapiens OX=9606 GN=AMBRA1 PE=1 SV=2 4.25 2159.1 - 369833 - - - -0.1609 - 2.425 0.61 - 427.9 1 2 0 -0.0002 13 0 0 0 6.97E+06 1.13E+07 - - - 5.8199 0.9999 221125_WJC_METTL3_EV_vs_WT_F05.10416.10416.3 5.99E-05 13/52 K.LDYGQHVVAGTPGR.V "sp|P38919|IF4A3_HUMAN,tr|I3L3H2|I3L3H2_HUMAN" 2 1468.7423 1.64 62769 10416 3 1468.741865 490.588 Eukaryotic initiation factor 4A-III OS=Homo sapiens OX=9606 GN=EIF4A3 PE=1 SV=4 6.74 2159.3 - 982295 - - - -0.2798 - 2.028 0.477 - 225.8 1 2 0 -0.0004 14 0 0 0 6.21E+07 3.80E+07 - - - 5.737 0.9995 221125_WJC_METTL3_EV_vs_WT_F05.10417.10417.2 0.000933 20-Dec K.ELEIGQAGSQR[166.11].A sp|Q15021|CND1_HUMAN 1 1196.6025 0.8 62770 10417 2 1196.599241 599.3085 Condensin complex subunit 1 OS=Homo sapiens OX=9606 GN=NCAPD2 PE=1 SV=3 4.53 2159.4 - 940664 - - - -2.711 - 2.305 0.441 - 623.5 1 2 0 -0.0032 11 0 0 0 1.69E+07 2.12E+07 - - - 4.5563 0.9833 221125_WJC_METTL3_EV_vs_WT_F05.10419.10419.3 0.017 Oct-32 K.FDEVFSNK[136.11]R[166.11].T sp|Q7Z5K2|WAPL_HUMAN 1 1158.5788 0.33 62772 10419 3 1158.578196 387.2002 Wings apart-like protein homolog OS=Homo sapiens OX=9606 GN=WAPL PE=1 SV=1 6.07 2159.6 - 698093 - - - -0.5584 - 1.851 0.099 - 112 1 2 0 -0.0006 9 0 0 0 2.86E+06 8.66E+06 - - - 1.4992 0.9315 221125_WJC_METTL3_EV_vs_WT_F05.10423.10423.2 0.00866 30-Jul R.ETGGAEGTGDAVLGEK[136.11].V "sp|Q92667|AKAP1_HUMAN,tr|I3L0W0|I3L0W0_HUMAN" 2 1497.7038 1.44 62774 10423 2 1497.690429 749.8592 "A-kinase anchor protein 1, mitochondrial OS=Homo sapiens OX=9606 GN=AKAP1 PE=1 SV=1" 4 2160.2 - 143422 - - - -8.9484 - 1.345 0.455 - 88.8 1 2 0 -0.0134 16 0 0 0 2.25E+06 1.56E+06 - - - 3.1261 0.9986 221125_WJC_METTL3_EV_vs_WT_F05.10424.10424.2 0.043 16-Aug R.R[166.11]PSVYLPTR[166.11].E sp|Q9BW61|DDA1_HUMAN 1 1107.6304 1.24 62775 10424 2 1107.63037 554.8225 DET1- and DDB1-associated protein 1 OS=Homo sapiens OX=9606 GN=DDA1 PE=1 SV=1 10.84 2160.3 - 1.21E+06 - - - 0.0018 - 1.369 0.287 - 95.4 1 2 0 0 9 0 0 0 2.94E+07 2.37E+07 - - - 2.0694 1 221125_WJC_METTL3_EV_vs_WT_F05.10425.10425.2 7.12E-07 16/34 R.PVSSAASVYAGAGGSGSR.L "sp|P05783|K1C18_HUMAN,tr|F8VZY9|F8VZY9_HUMAN" 2 1579.759 1.97 62776 10425 2 1579.758215 790.8868 "Keratin, type I cytoskeletal 18 OS=Homo sapiens OX=9606 GN=KRT18 PE=1 SV=2" 9.18 2160.4 - 330771 - - - -0.5273 - 3.488 0.634 - 679.3 1 1 0 -0.0008 18 0 0 0 5.02E+07 2.54E+07 - - - 6.795 1 221125_WJC_METTL3_EV_vs_WT_F05.10426.10426.2 1.81E-09 24-Nov K.LTESC[160.03]C[160.03]SSDAFER.L "sp|P82094|TMF1_HUMAN,tr|F8WF45|F8WF45_HUMAN,tr|A0A2R8Y7M0|A0A2R8Y7M0_HUMAN" 3 1560.6185 1.47 62777 10426 2 1560.614363 781.3165 TATA element modulatory factor OS=Homo sapiens OX=9606 GN=TMF1 PE=1 SV=2 4.14 2160.5 - 287853 - - - -2.624 - 2.446 0.796 - 582 1 2 0 -0.0041 13 0 0 0 3.04E+07 2.07E+07 - - - 7.2146 1 221125_WJC_METTL3_EV_vs_WT_F05.10427.10427.2 6.22E-11 19/34 R.PVSSAASVYAGAGGSGSR[166.11].L "sp|P05783|K1C18_HUMAN,tr|F8VZY9|F8VZY9_HUMAN" 2 1589.7673 1.97 62778 10427 2 1589.768818 795.8909 "Keratin, type I cytoskeletal 18 OS=Homo sapiens OX=9606 GN=KRT18 PE=1 SV=2" 9.18 2160.7 - 185398 - - - 0.9435 - 3.58 0.711 - 1020.5 1 1 0 0.0015 18 0 0 0 5.02E+07 2.54E+07 - - - 7.4275 0.9943 221125_WJC_METTL3_EV_vs_WT_F05.10431.10431.2 0.00566 20-Dec K.ELEIGQAGSQR.A sp|Q15021|CND1_HUMAN 1 1186.5942 0.8 62780 10431 2 1186.588367 594.3044 Condensin complex subunit 1 OS=Homo sapiens OX=9606 GN=NCAPD2 PE=1 SV=3 4.53 2161.2 - 769768 - - - -4.9284 - 2.15 0.327 - 540.5 1 2 0 -0.0058 11 0 0 0 1.69E+07 2.12E+07 - - - 3.5252 0.8492 221125_WJC_METTL3_EV_vs_WT_F05.10432.10432.2 0.143 14-Jun V.DTWESLQK.E "sp|Q9HAN9|NMNA1_HUMAN,tr|B1AN62|B1AN62_HUMAN" 2 1005.4767 2.07 62781 10432 2 1005.476545 503.7456 Nicotinamide\nicotinic acid mononucleotide adenylyltransferase 1 OS=Homo sapiens OX=9606 GN=NMNAT1 PE=1 SV=1 4.37 2161.4 - 639166 - - - -0.179 - 1.173 0.266 - 116.3 1 1 0 -0.0002 8 0 0 0 1.86E+07 9.02E+06 - - - 1.4869 0.9999 221125_WJC_METTL3_EV_vs_WT_F05.10433.10433.2 0.000214 13/20 K.TPVEPEVAIHR[166.11].L "sp|P60866|RS20_HUMAN,tr|E5RJX2|E5RJX2_HUMAN,tr|E5RIP1|E5RIP1_HUMAN,tr|A0A7P0S5H5|A0A7P0S5H5_HUMAN" 4 1256.6753 1.44 62782 10433 2 1256.676194 629.3449 40S ribosomal protein S20 OS=Homo sapiens OX=9606 GN=RPS20 PE=1 SV=1 5.37 2161.4 - 3.76E+06 - - - 0.7464 - 2.782 0.514 - 556 1 2 0 0.0009 11 0 0 0 1.03E+08 7.14E+07 - - - 5.605 0.9986 221125_WJC_METTL3_EV_vs_WT_F05.10434.10434.2 0.0142 16-Jul K.DLPEHAVLK[136.11].M "sp|Q00839|HNRPU_HUMAN,tr|A0A1W2PQL0|A0A1W2PQL0_HUMAN,tr|A0A1W2PPL4|A0A1W2PPL4_HUMAN,tr|A0A1W2PQ74|A0A1W2PQ74_HUMAN,tr|Q5RI18|Q5RI18_HUMAN,tr|A0A1W2PP35|A0A1W2PP35_HUMAN,tr|A0A1W2PPS1|A0A1W2PPS1_HUMAN,tr|A0A1W2PRZ7|A0A1W2PRZ7_HUMAN,tr|A0A1W2PPH7|A0A1W2PPH7_HUMAN,tr|A0A1W2PQD4|A0A1W2PQD4_HUMAN,tr|A0A1W2PP34|A0A1W2PP34_HUMAN,tr|A0A1X7SBS1|A0A1X7SBS1_HUMAN" 12 1028.5746 1.07 62783 10434 2 1028.575163 515.2946 Heterogeneous nuclear ribonucleoprotein U OS=Homo sapiens OX=9606 GN=HNRNPU PE=1 SV=6 5.32 2161.5 - 997578 - - - 0.5522 - 1.441 0.279 - 128.6 1 2 0 0.0006 9 0 0 0 5.13E+07 4.79E+07 - - - 2.1585 1 221125_WJC_METTL3_EV_vs_WT_F05.10435.10435.2 1.15E-10 24-Nov K.LTESC[160.03]C[160.03]SSDAFER[166.11].L "sp|P82094|TMF1_HUMAN,tr|F8WF45|F8WF45_HUMAN,tr|A0A2R8Y7M0|A0A2R8Y7M0_HUMAN" 3 1570.6267 1.47 62784 10435 2 1570.62689 786.3206 TATA element modulatory factor OS=Homo sapiens OX=9606 GN=TMF1 PE=1 SV=2 4.14 2161.6 - 458379 - - - 0.1031 - 2.626 0.748 - 542.4 1 2 0 0.0002 13 0 0 0 3.04E+07 2.07E+07 - - - 7.0436 0.9996 221125_WJC_METTL3_EV_vs_WT_F05.10438.10438.2 0.00082 20-Nov R.NLQEIQQAGER[166.11].L "sp|Q8N1F7|NUP93_HUMAN,tr|H3BM93|H3BM93_HUMAN,tr|H3BV11|H3BV11_HUMAN,tr|H3BRI8|H3BRI8_HUMAN,tr|H3BVG0|H3BVG0_HUMAN" 5 1294.6505 2.2 62786 10438 2 1294.650046 648.3325 Nuclear pore complex protein Nup93 OS=Homo sapiens OX=9606 GN=NUP93 PE=1 SV=2 4.53 2162 - 1.64E+06 - - - -0.3491 - 2.33 0.277 - 516.5 1 2 0 -0.0005 11 0 0 0 8.70E+07 3.96E+07 - - - 3.3751 0.9993 221125_WJC_METTL3_EV_vs_WT_F05.10439.10439.2 2.41E-06 20-Oct R.GTPDTDLEVQR.V sp|P0C7T5|ATX1L_HUMAN 1 1229.5888 2.16 62787 10439 2 1229.5878 615.8017 Ataxin-1-like OS=Homo sapiens OX=9606 GN=ATXN1L PE=1 SV=1 4.03 2162.1 - 579159 - - - -0.8092 - 2.116 0.236 - 543.5 1 2 0 -0.001 11 0 0 0 1.95E+07 9.01E+06 - - - 2.8114 1 221125_WJC_METTL3_EV_vs_WT_F05.10440.10440.3 9.21E-08 Dec-52 K.LDYGQHVVAGTPGR[166.11].V "sp|P38919|IF4A3_HUMAN,tr|I3L3H2|I3L3H2_HUMAN" 2 1478.7505 1.63 62788 10440 3 1478.751387 493.9241 Eukaryotic initiation factor 4A-III OS=Homo sapiens OX=9606 GN=EIF4A3 PE=1 SV=4 6.74 2162.2 - 2.43E+06 - - - 0.5687 - 2.42 0.527 - 208.5 1 2 0 0.0008 14 0 0 0 6.21E+07 3.81E+07 - - - 6.7639 0.9935 221125_WJC_METTL3_EV_vs_WT_F05.10442.10442.2 4.82E-05 14/22 K.ITDSAGHILYSK[136.11].E "sp|P49755|TMEDA_HUMAN,tr|G3V2K7|G3V2K7_HUMAN" 2 1311.6914 1.45 62790 10442 2 1311.700859 656.853 Transmembrane emp24 domain-containing protein 10 OS=Homo sapiens OX=9606 GN=TMED10 PE=1 SV=2 6.74 2162.4 - 344519 - - - 7.1991 - 2.681 0.541 - 534.9 1 2 0 0.0094 12 0 0 0 2.64E+07 1.83E+07 - - - 5.6287 0.9904 221125_WJC_METTL3_EV_vs_WT_F05.10446.10446.2 0.00183 12-Oct L.PEHAVLK[136.11].M "sp|Q00839|HNRPU_HUMAN,tr|A0A1W2PQL0|A0A1W2PQL0_HUMAN,tr|A0A1W2PPL4|A0A1W2PPL4_HUMAN,tr|A0A1W2PQ74|A0A1W2PQ74_HUMAN,tr|Q5RI18|Q5RI18_HUMAN,tr|A0A1W2PP35|A0A1W2PP35_HUMAN,tr|A0A1W2PPS1|A0A1W2PPS1_HUMAN,tr|A0A1W2PRZ7|A0A1W2PRZ7_HUMAN,tr|A0A1W2PPH7|A0A1W2PPH7_HUMAN,tr|A0A1W2PQD4|A0A1W2PQD4_HUMAN,tr|A0A1W2PP34|A0A1W2PP34_HUMAN,tr|A0A1X7SBS1|A0A1X7SBS1_HUMAN" 12 800.4636 1.1 62792 10446 2 800.464018 401.2391 Heterogeneous nuclear ribonucleoprotein U OS=Homo sapiens OX=9606 GN=HNRNPU PE=1 SV=6 7.17 2163 - 2.73E+06 - - - 0.5372 - 2.211 0.403 - 403.3 1 1 0 0.0004 7 0 0 0 7.59E+07 6.93E+07 - - - 4.5315 0.9985 221125_WJC_METTL3_EV_vs_WT_F05.10447.10447.2 0.0154 18-Sep K.SEFEQNLSEK[136.11].L "sp|Q16891|MIC60_HUMAN,tr|B9A067|B9A067_HUMAN,tr|C9J406|C9J406_HUMAN,tr|H7C463|H7C463_HUMAN" 4 1217.5655 1.38 62793 10447 2 1217.561748 609.79 MICOS complex subunit MIC60 OS=Homo sapiens OX=9606 GN=IMMT PE=1 SV=1 4.25 2163.1 - 1.01E+06 - - - -3.1202 - 1.902 0.369 - 254.4 1 2 0 -0.0038 10 0 0 0 4.07E+08 2.95E+08 - - - 3.5598 0.9971 221125_WJC_METTL3_EV_vs_WT_F05.10450.10450.3 0.0357 Sep-44 R.LTHYIEEANVGR.G "sp|Q5QP82|DCA10_HUMAN,tr|A0A0A0MQT4|A0A0A0MQT4_HUMAN" 2 1400.7048 0.54 62796 10450 3 1400.708094 467.9089 DDB1- and CUL4-associated factor 10 OS=Homo sapiens OX=9606 GN=DCAF10 PE=1 SV=1 5.4 2163.4 - 256336 - - - 2.3317 - 1.882 0.258 - 94.1 1 2 0 0.0033 12 0 0 0 6.65E+06 1.24E+07 - - - 3.1683 0.9983 221125_WJC_METTL3_EV_vs_WT_F05.10453.10453.2 0.216 16-Aug K.DLPEHAVLK.M "sp|Q00839|HNRPU_HUMAN,tr|A0A1W2PQL0|A0A1W2PQL0_HUMAN,tr|A0A1W2PPL4|A0A1W2PPL4_HUMAN,tr|A0A1W2PQ74|A0A1W2PQ74_HUMAN,tr|Q5RI18|Q5RI18_HUMAN,tr|A0A1W2PP35|A0A1W2PP35_HUMAN,tr|A0A1W2PPS1|A0A1W2PPS1_HUMAN,tr|A0A1W2PRZ7|A0A1W2PRZ7_HUMAN,tr|A0A1W2PPH7|A0A1W2PPH7_HUMAN,tr|A0A1W2PQD4|A0A1W2PQD4_HUMAN,tr|A0A1W2PP34|A0A1W2PP34_HUMAN,tr|A0A1X7SBS1|A0A1X7SBS1_HUMAN" 12 1020.5604 1.08 62797 10453 2 1020.560238 511.2875 Heterogeneous nuclear ribonucleoprotein U OS=Homo sapiens OX=9606 GN=HNRNPU PE=1 SV=6 5.32 2163.8 - 2.06E+06 - - - -0.1538 - 1.397 0.257 - 144.7 1 2 0 -0.0002 9 0 0 0 5.19E+07 4.80E+07 - - - 1.9064 1 221125_WJC_METTL3_EV_vs_WT_F05.10454.10454.2 0.000506 14/24 R.GTGEAEEEYVGPR.L "sp|Q13895|BYST_HUMAN,tr|F8WBL2|F8WBL2_HUMAN" 2 1392.6157 1.03 62798 10454 2 1392.614686 697.3151 Bystin OS=Homo sapiens OX=9606 GN=BYSL PE=1 SV=3 4.09 2163.9 - 1.77E+06 - - - -0.7554 - 2.737 0.586 - 867.3 1 2 0 -0.0011 13 0 0 0 2.95E+07 2.87E+07 - - - 5.953 0.9995 221125_WJC_METTL3_EV_vs_WT_F05.10455.10455.2 0.00683 18-Oct K.SEFEQNLSEK.L "sp|Q16891|MIC60_HUMAN,tr|B9A067|B9A067_HUMAN,tr|C9J406|C9J406_HUMAN,tr|H7C463|H7C463_HUMAN" 4 1209.5513 1.38 62799 10455 2 1209.549845 605.7829 MICOS complex subunit MIC60 OS=Homo sapiens OX=9606 GN=IMMT PE=1 SV=1 4.25 2164 - 2.14E+06 - - - -1.2418 - 1.814 0.367 - 419.9 1 2 0 -0.0015 10 0 0 0 4.07E+08 2.95E+08 - - - 3.4135 1 221125_WJC_METTL3_EV_vs_WT_F05.10457.10457.2 1.01E-08 14/24 K.ADEASELAC[160.03]PTPK.E "sp|P49327|FAS_HUMAN,tr|A0A0U1RQF0|A0A0U1RQF0_HUMAN" 2 1387.6289 0.75 62801 10457 2 1387.629835 694.8217 Fatty acid synthase OS=Homo sapiens OX=9606 GN=FASN PE=1 SV=3 4.14 2164.2 - 1.25E+06 - - - 0.6407 - 2.804 0.653 - 840.3 1 2 0 0.0009 13 0 0 0 2.75E+07 3.69E+07 - - - 6.51 0.9965 221125_WJC_METTL3_EV_vs_WT_F05.10458.10458.3 0.0106 18/36 T.PVEPEVAIHR[166.11].L "sp|P60866|RS20_HUMAN,tr|E5RJX2|E5RJX2_HUMAN,tr|E5RIP1|E5RIP1_HUMAN,tr|A0A7P0S5H5|A0A7P0S5H5_HUMAN" 4 1155.6276 1.15 62802 10458 3 1155.628138 386.2165 40S ribosomal protein S20 OS=Homo sapiens OX=9606 GN=RPS20 PE=1 SV=1 5.41 2164.3 - 735702 - - - 0.4855 - 3.016 0.413 - 790.5 1 1 0 0.0006 10 0 0 0 2.00E+07 1.73E+07 - - - 6.3683 1 221125_WJC_METTL3_EV_vs_WT_F05.10459.10459.2 3.34E-07 24-Nov R.FNTANDDNVTQVR.A sp|P04040|CATA_HUMAN 1 1492.6906 17.53 62803 10459 2 1492.689123 747.3526 Catalase OS=Homo sapiens OX=9606 GN=CAT PE=1 SV=3 4.21 2164.4 - 357788 - - - -1.0123 - 2.734 0.643 - 455.9 1 2 0 -0.0015 13 0 0 0 1.93E+07 1.10E+06 - - - 6.3711 0.9998 221125_WJC_METTL3_EV_vs_WT_F05.10462.10462.3 0.0382 Nov-36 K.LFK[136.11]PPQPPAR[166.11].M "sp|O15372|EIF3H_HUMAN,tr|B3KS98|B3KS98_HUMAN,tr|A0A087WZK9|A0A087WZK9_HUMAN" 3 1167.6883 1.91 62805 10462 3 1167.68815 390.2367 Eukaryotic translation initiation factor 3 subunit H OS=Homo sapiens OX=9606 GN=EIF3H PE=1 SV=1 11 2164.8 - 1.23E+06 - - - -0.1576 - 2.085 0.336 - 158.4 1 2 0 -0.0002 10 0 0 0 5.97E+07 3.13E+07 - - - 4.4319 0.9997 221125_WJC_METTL3_EV_vs_WT_F05.10463.10463.2 0.00458 18-Dec K.KVTLGDTLTR.R "sp|Q9UKV3|ACINU_HUMAN,tr|G3V3B0|G3V3B0_HUMAN,tr|S4R3H4|S4R3H4_HUMAN,tr|E7EQT4|E7EQT4_HUMAN" 4 1102.6346 1.39 62806 10463 2 1102.635361 552.3246 Apoptotic chromatin condensation inducer in the nucleus OS=Homo sapiens OX=9606 GN=ACIN1 PE=1 SV=2 8.75 2164.9 - 689707 - - - 0.6693 - 1.971 0.408 - 473.3 1 2 0 0.0007 10 0 0 0 3.32E+07 2.38E+07 - - - 3.9483 1 221125_WJC_METTL3_EV_vs_WT_F05.10464.10464.2 3.69E-05 16/20 R.ILNEMRDQYEK.M "sp|Q04695|K1C17_HUMAN,sp|P02533|K1C14_HUMAN,tr|K7EPJ9|K7EPJ9_HUMAN,tr|K7ESE1|K7ESE1_HUMAN,tr|F5GWP8|F5GWP8_HUMAN" 5 1437.6922 207.45 62807 10464 2 1437.691524 719.8534 "Keratin, type I cytoskeletal 17 OS=Homo sapiens OX=9606 GN=KRT17 PE=1 SV=2" 4.68 2165 - 1.09E+06 - - - -0.4799 - 2.925 0.516 - 963.2 1 2 1 -0.0007 11 0 0 0 1.43E+07 6.90E+04 - - - 5.7555 0.9999 221125_WJC_METTL3_EV_vs_WT_F05.10466.10466.3 6.92E-06 13/48 K.YYQTIGNHASYYK[136.11].D "sp|Q9UNM6|PSD13_HUMAN,tr|J3KNQ3|J3KNQ3_HUMAN,tr|E9PL38|E9PL38_HUMAN,tr|H0YD73|H0YD73_HUMAN,tr|A0A087WUL9|A0A087WUL9_HUMAN" 5 1614.7558 0.48 62809 10466 3 1614.755824 539.2592 26S proteasome non-ATPase regulatory subunit 13 OS=Homo sapiens OX=9606 GN=PSMD13 PE=1 SV=2 8.39 2165.3 - 524702 - - - 0.0105 - 1.985 0.464 - 96.2 1 2 0 0 13 0 0 0 1.69E+07 3.53E+07 - - - 5.572 0.8777 221125_WJC_METTL3_EV_vs_WT_F05.10467.10467.2 0.0618 16-Sep R.QHLLSLQQR.T "sp|P49750|YLPM1_HUMAN,tr|F8VU51|F8VU51_HUMAN" 2 1121.6305 0.1 62810 10467 2 1121.623267 561.8225 YLP motif-containing protein 1 OS=Homo sapiens OX=9606 GN=YLPM1 PE=1 SV=4 9.76 2165.4 - 376381 - - - -6.4852 - 1.517 0.183 - 319.3 1 2 0 -0.0073 9 0 0 0 6.84E+06 7.13E+07 - - - 1.596 0.9987 221125_WJC_METTL3_EV_vs_WT_F05.10468.10468.2 0.00521 13/24 R.AQQVAVQEQEIAR.R "sp|O75955|FLOT1_HUMAN,tr|A0A140T9W4|A0A140T9W4_HUMAN,tr|A2AB09|A2AB09_HUMAN,tr|A0A140T9R1|A0A140T9R1_HUMAN,tr|A0A140T9X0|A0A140T9X0_HUMAN,tr|A0A140T907|A0A140T907_HUMAN" 6 1468.7634 1.84 62811 10468 2 1468.757322 735.389 Flotillin-1 OS=Homo sapiens OX=9606 GN=FLOT1 PE=1 SV=3 4.53 2165.5 - 356990 - - - -4.1423 - 2.818 0.42 - 619.8 1 2 0 -0.0061 13 0 0 0 2.60E+07 1.41E+07 - - - 4.8002 1 221125_WJC_METTL3_EV_vs_WT_F05.10470.10470.3 1.39E-07 15/44 K.ITDSAGHILYSK[136.11].E "sp|P49755|TMEDA_HUMAN,tr|G3V2K7|G3V2K7_HUMAN" 2 1311.6914 1.45 62812 10470 3 1311.691347 438.2377 Transmembrane emp24 domain-containing protein 10 OS=Homo sapiens OX=9606 GN=TMED10 PE=1 SV=2 6.74 2165.8 - 1.23E+07 - - - -0.0526 - 3.18 0.54 - 480.2 1 2 0 -0.0001 12 0 0 0 2.32E+08 1.60E+08 - - - 7.7671 0.9867 221125_WJC_METTL3_EV_vs_WT_F05.10471.10471.2 1.36E-05 18-Nov T.PVEPEVAIHR.L "sp|P60866|RS20_HUMAN,tr|E5RJX2|E5RJX2_HUMAN,tr|E5RIP1|E5RIP1_HUMAN,tr|A0A7P0S5H5|A0A7P0S5H5_HUMAN" 4 1145.6193 1.35 62813 10471 2 1145.619994 573.8169 40S ribosomal protein S20 OS=Homo sapiens OX=9606 GN=RPS20 PE=1 SV=1 5.41 2165.9 - 428602 - - - 0.5997 - 2.316 0.365 - 494.9 1 1 0 0.0007 10 0 0 0 9.69E+06 7.20E+06 - - - 4.0809 1 221125_WJC_METTL3_EV_vs_WT_F05.10472.10472.2 5.62E-06 14/26 R.INGGGGGSVPGIER[166.11].M tr|M0QZM1|M0QZM1_HUMAN 1 1278.6556 1.5 62814 10472 2 1278.656115 640.3351 Heterogeneous nuclear ribonucleoprotein M (Fragment) OS=Homo sapiens OX=9606 GN=HNRNPM PE=1 SV=1 6 2166 - 1.45E+06 - - - 0.4161 - 2.995 0.593 - 581.1 1 2 0 0.0005 14 0 0 0 2.81E+08 1.87E+08 - - - 6.1735 0.9991 221125_WJC_METTL3_EV_vs_WT_F05.10473.10473.3 0.00282 13/48 K.YYQTIGNHASYYK.D "sp|Q9UNM6|PSD13_HUMAN,tr|J3KNQ3|J3KNQ3_HUMAN,tr|E9PL38|E9PL38_HUMAN,tr|H0YD73|H0YD73_HUMAN,tr|A0A087WUL9|A0A087WUL9_HUMAN" 5 1606.7416 0.48 62815 10473 3 1606.741377 536.5878 26S proteasome non-ATPase regulatory subunit 13 OS=Homo sapiens OX=9606 GN=PSMD13 PE=1 SV=2 8.39 2166.1 - 548360 - - - -0.1431 - 1.804 0.288 - 97.6 1 2 0 -0.0002 13 0 0 0 1.69E+07 3.53E+07 - - - 3.3505 0.9999 221125_WJC_METTL3_EV_vs_WT_F05.10474.10474.2 0.188 14/24 R.AQQVAVQEQEIAR[166.11].R "sp|O75955|FLOT1_HUMAN,tr|A0A140T9W4|A0A140T9W4_HUMAN,tr|A2AB09|A2AB09_HUMAN,tr|A0A140T9R1|A0A140T9R1_HUMAN,tr|A0A140T9X0|A0A140T9X0_HUMAN,tr|A0A140T907|A0A140T907_HUMAN" 6 1478.7717 1.84 62816 10474 2 1478.770604 740.3931 Flotillin-1 OS=Homo sapiens OX=9606 GN=FLOT1 PE=1 SV=3 4.53 2166.2 - 425030 - - - -0.7249 - 3.217 0.487 - 885.6 1 2 0 -0.0011 13 0 0 0 2.60E+07 1.41E+07 - - - 5.6365 0.9998 221125_WJC_METTL3_EV_vs_WT_F05.10476.10476.2 0.0434 18-Oct R.VHIDIGADGR[166.11].A sp|P31942|HNRH3_HUMAN 1 1061.5493 2.25 62817 10476 2 1061.548911 531.7819 Heterogeneous nuclear ribonucleoprotein H3 OS=Homo sapiens OX=9606 GN=HNRNPH3 PE=1 SV=2 5.21 2166.4 - 1.79E+06 - - - -0.3919 - 1.961 0.395 - 446.1 1 2 0 -0.0004 10 0 0 0 8.91E+07 3.97E+07 - - - 3.8382 1 221125_WJC_METTL3_EV_vs_WT_F05.10483.10483.2 1.51E-07 14/26 R.INGGGGGSVPGIER.M tr|M0QZM1|M0QZM1_HUMAN 1 1268.6473 1.51 62821 10483 2 1268.64433 635.3309 Heterogeneous nuclear ribonucleoprotein M (Fragment) OS=Homo sapiens OX=9606 GN=HNRNPM PE=1 SV=1 6 2167.3 - 3.04E+06 - - - -2.3513 - 2.885 0.635 - 596.8 1 2 0 -0.003 14 0 0 0 2.81E+08 1.87E+08 - - - 6.389 0.9999 221125_WJC_METTL3_EV_vs_WT_F05.10485.10485.2 5.99E-07 24-Nov R.GTGEAEEEYVGPR[166.11].L "sp|Q13895|BYST_HUMAN,tr|F8WBL2|F8WBL2_HUMAN" 2 1402.624 1.03 62823 10485 2 1402.625262 702.3193 Bystin OS=Homo sapiens OX=9606 GN=BYSL PE=1 SV=3 4.09 2167.4 - 1.05E+06 - - - 0.894 - 2.39 0.525 - 471.6 1 2 0 0.0013 13 0 0 0 2.95E+07 2.87E+07 - - - 5.1545 0.9994 221125_WJC_METTL3_EV_vs_WT_F05.10486.10486.2 0.000914 22-Oct K.AGNSC[160.03]PELVPSR[166.11].R "sp|O75410|TACC1_HUMAN,tr|E7EVI4|E7EVI4_HUMAN,tr|E5RIP3|E5RIP3_HUMAN,tr|E5RJU4|E5RJU4_HUMAN,tr|E5RFM9|E5RFM9_HUMAN,tr|R4GMT7|R4GMT7_HUMAN,tr|E7ET87|E7ET87_HUMAN" 7 1295.6168 1.11 62824 10486 2 1295.613266 648.8157 Transforming acidic coiled-coil-containing protein 1 OS=Homo sapiens OX=9606 GN=TACC1 PE=1 SV=2 6.04 2167.6 - 380504 - - - -2.6929 - 2.105 0.447 - 293.4 1 2 0 -0.0035 12 0 0 0 1.80E+07 1.62E+07 - - - 4.2999 1 221125_WJC_METTL3_EV_vs_WT_F05.10487.10487.2 1.95E-06 18-Nov T.DSAGHILYSK.E "sp|P49755|TMEDA_HUMAN,tr|G3V2K7|G3V2K7_HUMAN" 2 1089.5455 1.6 62825 10487 2 1089.547915 545.78 Transmembrane emp24 domain-containing protein 10 OS=Homo sapiens OX=9606 GN=TMED10 PE=1 SV=2 6.74 2167.7 - 332549 - - - 2.2404 - 2.417 0.582 - 443.7 1 1 0 0.0024 10 0 0 0 4.93E+06 3.08E+06 - - - 5.8023 1 221125_WJC_METTL3_EV_vs_WT_F05.10494.10494.2 1.58E-08 20-Dec R.SGQGAFGNMC[160.03]R.G "sp|P36578|RL4_HUMAN,tr|H3BTP7|H3BTP7_HUMAN,tr|H3BU31|H3BU31_HUMAN" 3 1183.4863 1.17 62830 10494 2 1183.486467 592.7504 60S ribosomal protein L4 OS=Homo sapiens OX=9606 GN=RPL4 PE=1 SV=5 7.96 2168.6 - 1.36E+06 - - - 0.1741 - 2.306 0.67 - 550.5 1 2 0 0.0002 11 0 0 0 1.46E+07 1.24E+07 - - - 6.2498 0.9999 221125_WJC_METTL3_EV_vs_WT_F05.10498.10498.2 2.41E-05 22-Dec R.TNLDESDVQPVK.E sp|Q9Y3I0|RTCB_HUMAN 1 1343.6569 1.62 62834 10498 2 1343.657692 672.8357 RNA-splicing ligase RtcB homolog OS=Homo sapiens OX=9606 GN=RTCB PE=1 SV=1 4.03 2169 - 688310 - - - 0.608 - 2.441 0.487 - 399.2 1 2 0 0.0008 12 0 0 0 8.34E+07 5.13E+07 - - - 4.9858 0.999 221125_WJC_METTL3_EV_vs_WT_F05.10499.10499.2 0.145 16-Oct R.KQQLEVELR.Q sp|P15924|DESP_HUMAN 1 1141.6455 9.78 62835 10499 2 1141.64583 571.83 Desmoplakin OS=Homo sapiens OX=9606 GN=DSP PE=1 SV=3 6.14 2169.2 - 503425 - - - 0.2698 - 1.993 0.179 - 351.3 1 2 0 0.0003 9 0 0 0 7.35E+06 7.52E+05 - - - 2.3582 0.9961 221125_WJC_METTL3_EV_vs_WT_F05.10500.10500.3 0.118 Sep-40 R.QPEGTPLNHFR.R sp|Q6P2E9|EDC4_HUMAN 1 1294.6418 4.92 62836 10500 3 1294.640526 432.5546 Enhancer of mRNA-decapping protein 4 OS=Homo sapiens OX=9606 GN=EDC4 PE=1 SV=1 6.75 2169.3 - 414741 - - - -1.0103 - 1.681 0.214 - 122 1 2 0 -0.0013 11 0 0 0 1.90E+07 3.86E+06 - - - 2.401 0.9733 221125_WJC_METTL3_EV_vs_WT_F05.10501.10501.2 2.18E-05 18-Sep T.DSAGHILYSK[136.11].E "sp|P49755|TMEDA_HUMAN,tr|G3V2K7|G3V2K7_HUMAN" 2 1097.5597 1.67 62837 10501 2 1097.561974 549.7871 Transmembrane emp24 domain-containing protein 10 OS=Homo sapiens OX=9606 GN=TMED10 PE=1 SV=2 6.74 2169.4 - 289721 - - - 2.0956 - 1.923 0.45 - 211.9 1 1 0 0.0023 10 0 0 0 5.14E+06 3.08E+06 - - - 4.1892 0.7838 221125_WJC_METTL3_EV_vs_WT_F05.10502.10502.2 0.00958 16-Aug V.VWVEESDKR.S "sp|O00571|DDX3X_HUMAN,tr|A0A2R8YFR4|A0A2R8YFR4_HUMAN,tr|A0A2R8YCW1|A0A2R8YCW1_HUMAN,tr|A0A2R8YDH3|A0A2R8YDH3_HUMAN,tr|A0A2R8YDT5|A0A2R8YDT5_HUMAN,tr|A0A2R8Y645|A0A2R8Y645_HUMAN,tr|A0A2R8YF78|A0A2R8YF78_HUMAN,tr|A0A0D9SFB3|A0A0D9SFB3_HUMAN,tr|A0A2R8YFS5|A0A2R8YFS5_HUMAN,tr|A0A0D9SF53|A0A0D9SF53_HUMAN,tr|A0A0J9YVQ7|A0A0J9YVQ7_HUMAN,tr|A0A2R8Y5G6|A0A2R8Y5G6_HUMAN,tr|A0A2R8Y7T2|A0A2R8Y7T2_HUMAN,tr|A0A0D9SG12|A0A0D9SG12_HUMAN,tr|F6S8Q4|F6S8Q4_HUMAN,tr|A0A2U3TZJ9|A0A2U3TZJ9_HUMAN,tr|A0A2R8Y4A4|A0A2R8Y4A4_HUMAN" 17 1146.5669 0.53 62838 10502 2 1146.562337 574.2907 ATP-dependent RNA helicase DDX3X OS=Homo sapiens OX=9606 GN=DDX3X PE=1 SV=3 4.68 2169.5 - 254015 - - - -4.012 - 1.704 0.334 - 302.4 1 1 0 -0.0046 9 0 0 0 6.04E+06 1.13E+07 - - - 3.0484 0.9992 221125_WJC_METTL3_EV_vs_WT_F05.10505.10505.3 0.0312 Oct-36 K.VVWVEESDK[136.11]R[166.11].S "sp|O00571|DDX3X_HUMAN,tr|A0A2R8YFR4|A0A2R8YFR4_HUMAN,tr|A0A2R8YCW1|A0A2R8YCW1_HUMAN,tr|A0A2R8YDH3|A0A2R8YDH3_HUMAN,tr|A0A2R8YDT5|A0A2R8YDT5_HUMAN,tr|A0A2R8Y645|A0A2R8Y645_HUMAN,tr|A0A2R8YF78|A0A2R8YF78_HUMAN,tr|A0A0D9SFB3|A0A0D9SFB3_HUMAN,tr|A0A2R8YFS5|A0A2R8YFS5_HUMAN,tr|A0A0D9SF53|A0A0D9SF53_HUMAN,tr|A0A0J9YVQ7|A0A0J9YVQ7_HUMAN,tr|A0A2R8Y5G6|A0A2R8Y5G6_HUMAN,tr|A0A2R8Y7T2|A0A2R8Y7T2_HUMAN,tr|A0A0D9SG12|A0A0D9SG12_HUMAN,tr|F6S8Q4|F6S8Q4_HUMAN,tr|A0A2U3TZJ9|A0A2U3TZJ9_HUMAN,tr|A0A2R8Y4A4|A0A2R8Y4A4_HUMAN" 17 1263.6578 1.2 62840 10505 3 1263.656856 422.2266 ATP-dependent RNA helicase DDX3X OS=Homo sapiens OX=9606 GN=DDX3X PE=1 SV=3 4.68 2169.9 - 4.66E+06 - - - -0.7637 - 1.935 0.271 - 167.4 1 2 0 -0.001 10 0 0 0 1.21E+08 1.01E+08 - - - 3.4889 0.9998 221125_WJC_METTL3_EV_vs_WT_F05.10507.10507.3 0.0127 Dec-40 R.GC[160.03]HLLVATPGR[166.11].L "sp|O00571|DDX3X_HUMAN,sp|O15523|DDX3Y_HUMAN,tr|A0A2R8YFR4|A0A2R8YFR4_HUMAN,tr|A0A2R8YCW1|A0A2R8YCW1_HUMAN,tr|A0A2R8YDH3|A0A2R8YDH3_HUMAN,tr|A0A2R8YDT5|A0A2R8YDT5_HUMAN,tr|A0A2R8Y645|A0A2R8Y645_HUMAN,tr|A0A2R8YF78|A0A2R8YF78_HUMAN,tr|A0A0D9SFB3|A0A0D9SFB3_HUMAN,tr|A0A2R8YFS5|A0A2R8YFS5_HUMAN,tr|A0A0D9SF53|A0A0D9SF53_HUMAN,tr|A0A2R8Y5G6|A0A2R8Y5G6_HUMAN,tr|A0A2R8Y7T2|A0A2R8Y7T2_HUMAN,tr|A0A0D9SG12|A0A0D9SG12_HUMAN,tr|F6S8Q4|F6S8Q4_HUMAN,tr|A0A2U3TZJ9|A0A2U3TZJ9_HUMAN,tr|A0A2R8Y4A4|A0A2R8Y4A4_HUMAN" 17 1189.6265 1.01 62841 10507 3 1189.62625 397.5495 ATP-dependent RNA helicase DDX3X OS=Homo sapiens OX=9606 GN=DDX3X PE=1 SV=3 8.26 2170.1 - 3.09E+06 - - - -0.237 - 2.157 0.332 - 295.6 1 2 0 -0.0003 11 0 0 0 5.81E+07 5.73E+07 - - - 4.4252 1 221125_WJC_METTL3_EV_vs_WT_F05.10511.10511.3 1.74E-05 Nov-40 K.K[136.11]VTQLDLDGPK[136.11].E sp|Q13442|HAP28_HUMAN 1 1228.6998 0.58 62845 10511 3 1228.700344 410.5739 28 kDa heat- and acid-stable phosphoprotein OS=Homo sapiens OX=9606 GN=PDAP1 PE=1 SV=1 5.96 2170.5 - 791441 - - - 0.4403 - 2.28 0.516 - 196.1 1 2 0 0.0005 11 0 0 0 1.34E+07 2.33E+07 - - - 6.6341 0.9988 221125_WJC_METTL3_EV_vs_WT_F05.10512.10512.2 0.00122 22-Nov K.AGNSC[160.03]PELVPSR.R "sp|O75410|TACC1_HUMAN,tr|E7EVI4|E7EVI4_HUMAN,tr|E5RIP3|E5RIP3_HUMAN,tr|E5RJU4|E5RJU4_HUMAN,tr|E5RFM9|E5RFM9_HUMAN,tr|R4GMT7|R4GMT7_HUMAN,tr|E7ET87|E7ET87_HUMAN" 7 1285.6085 1.09 62846 10512 2 1285.613503 643.8115 Transforming acidic coiled-coil-containing protein 1 OS=Homo sapiens OX=9606 GN=TACC1 PE=1 SV=2 6.04 2170.6 - 602168 - - - 3.9032 - 2.193 0.481 - 337.9 1 2 0 0.005 12 0 0 0 1.76E+07 1.61E+07 - - - 4.6583 0.9992 221125_WJC_METTL3_EV_vs_WT_F05.10514.10514.2 0.00114 20-Jun K.MSISEGTVSDK.S sp|P46821|MAP1B_HUMAN 1 1152.5333 0.82 62848 10514 2 1152.531394 577.2739 Microtubule-associated protein 1B OS=Homo sapiens OX=9606 GN=MAP1B PE=1 SV=2 4.37 2170.8 - 252852 - - - -1.6138 - 1.538 0.394 - 79.4 1 2 0 -0.0019 11 0 0 0 2.79E+06 3.38E+06 - - - 3.1151 0.9998 221125_WJC_METTL3_EV_vs_WT_F05.10515.10515.2 3.18E-05 22-Dec K.LC[160.03]EC[160.03]SFNDPNAK[136.11].E sp|Q96KR1|ZFR_HUMAN 1 1461.6108 1.41 62849 10515 2 1461.609592 731.8127 Zinc finger RNA-binding protein OS=Homo sapiens OX=9606 GN=ZFR PE=1 SV=2 4.37 2171 - 132650 - - - -0.8265 - 2.097 0.496 - 493.6 1 2 0 -0.0012 12 0 0 0 6.23E+06 4.41E+06 - - - 4.6525 0.9999 221125_WJC_METTL3_EV_vs_WT_F05.10518.10518.3 9.45E-05 Oct-40 K.K[136.11]ATVNLLGEEK[136.11].K sp|Q00765|REEP5_HUMAN 1 1216.6998 0.57 62850 10518 3 1216.698996 406.5739 Receptor expression-enhancing protein 5 OS=Homo sapiens OX=9606 GN=REEP5 PE=1 SV=3 6.14 2171.4 - 799516 - - - -0.6633 - 2.165 0.4 - 115.6 1 2 0 -0.0008 11 0 0 0 7.42E+06 1.30E+07 - - - 5.1937 0.9993 221125_WJC_METTL3_EV_vs_WT_F05.10519.10519.2 0.00117 16-Dec K.K[136.11]GDIIQLQR[166.11].R "sp|P07814|SYEP_HUMAN,tr|V9GYZ6|V9GYZ6_HUMAN" 2 1087.6469 0.99 62851 10519 2 1087.649092 544.8307 Bifunctional glutamate\proline--tRNA ligase OS=Homo sapiens OX=9606 GN=EPRS1 PE=1 SV=5 8.75 2171.5 - 557093 - - - 2.0494 - 2.028 0.334 - 569.1 1 2 0 0.0022 9 0 0 0 7.65E+06 7.73E+06 - - - 3.5528 0.9997 221125_WJC_METTL3_EV_vs_WT_F05.10520.10520.3 0.0246 15/44 K.EAALSTALSEKR.T "sp|P02545|LMNA_HUMAN,tr|A0A6Q8PF80|A0A6Q8PF80_HUMAN,tr|A0A804HL68|A0A804HL68_HUMAN,tr|Q5TCI8|Q5TCI8_HUMAN,tr|A0A6Q8PFJ0|A0A6Q8PFJ0_HUMAN,tr|A0A6Q8PHQ9|A0A6Q8PHQ9_HUMAN,tr|A0A6Q8PGH0|A0A6Q8PGH0_HUMAN,tr|Q3BDU5|Q3BDU5_HUMAN" 8 1274.683 4.5 62852 10520 3 1274.684479 425.9016 Prelamin-A\C OS=Homo sapiens OX=9606 GN=LMNA PE=1 SV=1 6.24 2171.6 - 718088 - - - 1.1368 - 2.524 0.282 - 300.7 1 2 0 0.0014 12 0 0 0 1.28E+07 2.85E+06 - - - 4.2499 0.9998 221125_WJC_METTL3_EV_vs_WT_F05.10521.10521.3 0.00595 Dec-44 K.ISHATEELETYR.K "sp|A4FU28|CTGE9_HUMAN,sp|Q96RT6|CTGE2_HUMAN,sp|Q96PC5|MIA2_HUMAN,tr|G3V599|G3V599_HUMAN" 4 1447.6943 0.66 62853 10521 3 1447.6945 483.5721 cTAGE family member 9 OS=Homo sapiens OX=9606 GN=CTAGE9 PE=2 SV=2 4.75 2171.8 - 422673 - - - 0.1223 - 2.118 0.361 - 332.1 1 2 0 0.0002 12 0 0 0 3.52E+06 5.31E+06 - - - 4.6449 0.9999 221125_WJC_METTL3_EV_vs_WT_F05.10522.10522.2 4.21E-06 22-Oct K.LC[160.03]EC[160.03]SFNDPNAK.E sp|Q96KR1|ZFR_HUMAN 1 1453.5966 1.41 62854 10522 2 1453.596091 727.8056 Zinc finger RNA-binding protein OS=Homo sapiens OX=9606 GN=ZFR PE=1 SV=2 4.37 2171.9 - 403431 - - - -0.3502 - 2.014 0.621 - 269.9 1 2 0 -0.0005 12 0 0 0 6.23E+06 4.41E+06 - - - 5.4697 1 221125_WJC_METTL3_EV_vs_WT_F05.10523.10523.2 1.55E-05 13/30 K.QVLVAPGNAGTAC[160.03]SEK.L "sp|P22102|PUR2_HUMAN,tr|F8WD69|F8WD69_HUMAN,tr|C9JKQ7|C9JKQ7_HUMAN,tr|C9JZG2|C9JZG2_HUMAN,tr|C9JTV6|C9JTV6_HUMAN,tr|C9JBJ1|C9JBJ1_HUMAN" 6 1600.7879 0.9 62855 10523 2 1600.787203 801.4012 Trifunctional purine biosynthetic protein adenosine-3 OS=Homo sapiens OX=9606 GN=GART PE=1 SV=1 5.99 2172 - 325011 - - - -0.4392 - 2.809 0.571 - 414 1 2 0 -0.0007 16 0 0 0 8.12E+06 9.07E+06 - - - 5.7974 0.9987 221125_WJC_METTL3_EV_vs_WT_F05.10524.10524.2 0.0342 18-Aug K.VTILQSSDSR.A "sp|Q9ULV3|CIZ1_HUMAN,tr|Q5SYW2|Q5SYW2_HUMAN,tr|F5H2X7|F5H2X7_HUMAN,tr|H0Y5D5|H0Y5D5_HUMAN,tr|A0A494C0L7|A0A494C0L7_HUMAN,tr|Q9BTG3|Q9BTG3_HUMAN" 6 1104.5775 1.85 62856 10524 2 1104.576719 553.296 Cip1-interacting zinc finger protein OS=Homo sapiens OX=9606 GN=CIZ1 PE=1 SV=2 5.81 2172.2 - 275521 - - - -0.7089 - 1.662 0.241 - 247.6 1 2 0 -0.0008 10 0 0 0 3.42E+06 1.85E+06 - - - 2.2388 0.9995 221125_WJC_METTL3_EV_vs_WT_F05.10526.10526.2 0.000558 18-Aug K.YLQSNSNNWR[166.11].W sp|Q7Z6Z7|HUWE1_HUMAN 1 1290.5981 0.04 62858 10526 2 1290.600691 646.3063 E3 ubiquitin-protein ligase HUWE1 OS=Homo sapiens OX=9606 GN=HUWE1 PE=1 SV=3 8.75 2172.4 - 166167 - - - 2.0324 - 1.44 0.522 - 196.7 1 2 0 0.0026 10 0 0 0 9.91E+04 2.29E+06 - - - 3.9135 0.9999 221125_WJC_METTL3_EV_vs_WT_F05.10527.10527.2 1.21E-05 24-Nov R.VGEAQETTEEFNR[166.11].E "sp|O95273|CCDB1_HUMAN,tr|H3BR23|H3BR23_HUMAN,tr|H3BQA6|H3BQA6_HUMAN" 3 1518.6826 1.38 62859 10527 2 1518.682592 760.3486 Cyclin-D1-binding protein 1 OS=Homo sapiens OX=9606 GN=CCNDBP1 PE=1 SV=2 4.09 2172.6 - 178455 - - - 0.004 - 1.956 0.569 - 229.9 1 2 0 0 13 0 0 0 1.25E+06 9.05E+05 - - - 4.9655 1 221125_WJC_METTL3_EV_vs_WT_F05.10529.10529.3 5.87E-05 13/40 R.GC[160.03]HLLVATPGR.L "sp|O00571|DDX3X_HUMAN,sp|O15523|DDX3Y_HUMAN,tr|A0A2R8YFR4|A0A2R8YFR4_HUMAN,tr|A0A2R8YCW1|A0A2R8YCW1_HUMAN,tr|A0A2R8YDH3|A0A2R8YDH3_HUMAN,tr|A0A2R8YDT5|A0A2R8YDT5_HUMAN,tr|A0A2R8Y645|A0A2R8Y645_HUMAN,tr|A0A2R8YF78|A0A2R8YF78_HUMAN,tr|A0A0D9SFB3|A0A0D9SFB3_HUMAN,tr|A0A2R8YFS5|A0A2R8YFS5_HUMAN,tr|A0A0D9SF53|A0A0D9SF53_HUMAN,tr|A0A2R8Y5G6|A0A2R8Y5G6_HUMAN,tr|A0A2R8Y7T2|A0A2R8Y7T2_HUMAN,tr|A0A0D9SG12|A0A0D9SG12_HUMAN,tr|F6S8Q4|F6S8Q4_HUMAN,tr|A0A2U3TZJ9|A0A2U3TZJ9_HUMAN,tr|A0A2R8Y4A4|A0A2R8Y4A4_HUMAN" 17 1179.6183 0.93 62860 10529 3 1179.618765 394.2134 ATP-dependent RNA helicase DDX3X OS=Homo sapiens OX=9606 GN=DDX3X PE=1 SV=3 8.26 2172.8 - 3.25E+06 - - - 0.4264 - 2.845 0.429 - 322.4 1 2 0 0.0005 11 0 0 0 5.30E+07 5.67E+07 - - - 6.2931 0.9999 221125_WJC_METTL3_EV_vs_WT_F05.10530.10530.2 3.28E-07 13/22 R.TNLDESDVQPVK[136.11].E sp|Q9Y3I0|RTCB_HUMAN 1 1351.6711 1.62 62861 10530 2 1351.670704 676.8428 RNA-splicing ligase RtcB homolog OS=Homo sapiens OX=9606 GN=RTCB PE=1 SV=1 4.03 2172.9 - 2.68E+06 - - - -0.2745 - 2.457 0.547 - 596.1 1 2 0 -0.0004 12 0 0 0 8.33E+07 5.13E+07 - - - 5.4463 1 221125_WJC_METTL3_EV_vs_WT_F05.10531.10531.3 0.00326 14/40 K.VADMALHYANK[136.11].Y "sp|P50990|TCPQ_HUMAN,tr|H7C4C8|H7C4C8_HUMAN" 2 1239.6161 0.27 62862 10531 3 1239.615606 414.2127 T-complex protein 1 subunit theta OS=Homo sapiens OX=9606 GN=CCT8 PE=1 SV=4 6.71 2172.9 - 5.79E+06 - - - -0.4332 - 2.868 0.472 - 418.7 1 2 0 -0.0005 11 0 0 0 1.91E+07 7.03E+07 - - - 6.7953 1 221125_WJC_METTL3_EV_vs_WT_F05.10532.10532.3 2.73E-07 13/44 K.LSAMMGAVAEK[136.11]K[136.11].G "sp|Q86U44|MTA70_HUMAN,tr|F5H6D8|F5H6D8_HUMAN,tr|H0YFV6|H0YFV6_HUMAN,tr|B4DTN4|B4DTN4_HUMAN" 4 1250.6698 0.04 62863 10532 3 1250.668849 417.8972 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 8.59 2172.9 - 3.98E+06 - - - -0.7324 - 2.551 0.485 - 216.1 1 2 0 -0.0009 12 0 0 0 3.20E+06 7.50E+07 - - - 6.5428 0.9999 221125_WJC_METTL3_EV_vs_WT_F05.10533.10533.3 1.50E-05 14/56 K.VGAHAGEYGAEALER.M "sp|P69905|HBA_HUMAN,tr|A0A2R8Y7C0|A0A2R8Y7C0_HUMAN" 2 1528.727 14.36 62864 10533 3 1528.730153 510.5829 Hemoglobin subunit alpha OS=Homo sapiens OX=9606 GN=HBA1 PE=1 SV=2 4.75 2173 - 1.45E+06 - - - 2.0494 - 2.933 0.435 - 319.2 1 2 0 0.0031 15 0 0 0 1.40E+07 9.77E+05 - - - 6.1967 0.999 221125_WJC_METTL3_EV_vs_WT_F05.10535.10535.3 0.00477 Oct-40 R.ILK[136.11]EEQELYQK[136.11].E "sp|Q9UM54|MYO6_HUMAN,tr|A0A590UK86|A0A590UK86_HUMAN,tr|A0A590UK71|A0A590UK71_HUMAN,tr|A0A0D9SGC1|A0A0D9SGC1_HUMAN,tr|A0A0A0MRM8|A0A0A0MRM8_HUMAN,tr|A0A5F9ZI03|A0A5F9ZI03_HUMAN,tr|A0A590UK22|A0A590UK22_HUMAN,tr|A0A590UJY4|A0A590UJY4_HUMAN,tr|A0A590UJ40|A0A590UJ40_HUMAN,tr|A0A590UJ75|A0A590UJ75_HUMAN,tr|E7EW20|E7EW20_HUMAN,tr|A0A590UKB0|A0A590UKB0_HUMAN,tr|A0A1Y0BRN3|A0A1Y0BRN3_HUMAN" 13 1435.7893 0.45 62866 10535 3 1435.788911 479.6037 Unconventional myosin-VI OS=Homo sapiens OX=9606 GN=MYO6 PE=1 SV=4 4.79 2173.2 - 735571 - - - -0.303 - 1.983 0.357 - 104.9 1 2 1 -0.0004 11 0 0 0 3.96E+06 8.91E+06 - - - 4.4649 0.9848 221125_WJC_METTL3_EV_vs_WT_F05.10537.10537.2 0.00229 22-Nov R.QQPDTEAVLNGK[136.11].G "sp|P54105|ICLN_HUMAN,tr|E9PJF4|E9PJF4_HUMAN,tr|J3KN38|J3KN38_HUMAN,tr|E9PMI6|E9PMI6_HUMAN,tr|E9PQ83|E9PQ83_HUMAN" 5 1306.6608 2.2 62868 10537 2 1306.653119 654.3377 Methylosome subunit pICln OS=Homo sapiens OX=9606 GN=CLNS1A PE=1 SV=1 4.37 2173.4 - 197049 - - - -5.912 - 1.805 0.353 - 504.4 1 2 0 -0.0077 12 0 0 0 6.04E+06 2.75E+06 - - - 3.1997 0.9994 221125_WJC_METTL3_EV_vs_WT_F05.10542.10542.3 0.00289 13/40 R.ELEAELEDERK.Q sp|P35580|MYH10_HUMAN 1 1359.6518 1.25 62871 10542 3 1359.656024 454.2245 Myosin-10 OS=Homo sapiens OX=9606 GN=MYH10 PE=1 SV=3 4.14 2174.1 - 1.46E+06 - - - 3.1148 - 2.267 0.358 - 261.4 1 2 0 0.0042 11 0 0 0 3.76E+07 3.01E+07 - - - 4.8553 0.9997 221125_WJC_METTL3_EV_vs_WT_F05.10543.10543.2 0.00149 20-Dec R.TNLATGIPSSK.V "sp|Q96A57|TM230_HUMAN,tr|A0A087WTT2|A0A087WTT2_HUMAN,tr|Q5JWB9|Q5JWB9_HUMAN" 3 1087.5873 1.06 62872 10543 2 1087.588055 544.8009 Transmembrane protein 230 OS=Homo sapiens OX=9606 GN=TMEM230 PE=1 SV=1 8.41 2174.2 - 935564 - - - 0.6583 - 2.082 0.377 - 545.7 1 2 0 0.0007 11 0 0 0 1.79E+07 1.69E+07 - - - 3.8091 1 221125_WJC_METTL3_EV_vs_WT_F05.10544.10544.3 0.000175 Dec-40 K.VADMALHYANK.Y "sp|P50990|TCPQ_HUMAN,tr|H7C4C8|H7C4C8_HUMAN" 2 1231.6019 0.27 62873 10544 3 1231.600366 411.5413 T-complex protein 1 subunit theta OS=Homo sapiens OX=9606 GN=CCT8 PE=1 SV=4 6.71 2174.2 - 2.53E+06 - - - -1.2804 - 2.235 0.487 - 179.7 1 2 0 -0.0016 11 0 0 0 1.91E+07 7.00E+07 - - - 6.2538 1 221125_WJC_METTL3_EV_vs_WT_F05.10545.10545.2 1.79E-08 13/26 Y.EIDAC[160.03]MDSEAPGSK[136.11].D "sp|Q86U44|MTA70_HUMAN,tr|H0YFV6|H0YFV6_HUMAN" 2 1516.6265 0.02 62874 10545 2 1517.62685 759.3205 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 3.92 2174.3 - 1.03E+06 - - - 659.583 - 2.533 0.647 - 404.6 1 1 0 1.0003 14 0 0 0 8.28E+06 4.39E+08 - - - 5.8379 0.9999 221125_WJC_METTL3_EV_vs_WT_F05.10546.10546.3 4.49E-08 17/44 K.VSSVFKDEATVR.M sp|P46060|RAGP1_HUMAN 1 1336.6987 1.15 62875 10546 3 1336.698556 446.5735 Ran GTPase-activating protein 1 OS=Homo sapiens OX=9606 GN=RANGAP1 PE=1 SV=1 6.04 2174.4 - 767751 - - - -0.0928 - 3.013 0.492 - 641.2 1 2 1 -0.0001 12 0 0 0 2.54E+07 2.21E+07 - - - 7.0825 0.9999 221125_WJC_METTL3_EV_vs_WT_F05.10547.10547.2 6.46E-08 14/30 K.QVLVAPGNAGTAC[160.03]SEK[136.11].L "sp|P22102|PUR2_HUMAN,tr|F8WD69|F8WD69_HUMAN,tr|C9JKQ7|C9JKQ7_HUMAN,tr|C9JZG2|C9JZG2_HUMAN,tr|C9JTV6|C9JTV6_HUMAN,tr|C9JBJ1|C9JBJ1_HUMAN" 6 1608.8021 0.9 62876 10547 2 1608.803629 805.4083 Trifunctional purine biosynthetic protein adenosine-3 OS=Homo sapiens OX=9606 GN=GART PE=1 SV=1 5.99 2174.6 - 569890 - - - 0.9467 - 2.89 0.5 - 512.7 1 2 0 0.0015 16 0 0 0 8.12E+06 9.07E+06 - - - 5.3427 0.9998 221125_WJC_METTL3_EV_vs_WT_F05.10549.10549.2 1.02E-05 18-Oct R.C[160.03]SNPLDTSVK.E "sp|P17812|PYRG1_HUMAN,tr|A0A3B3ITF6|A0A3B3ITF6_HUMAN,tr|B4E1E0|B4E1E0_HUMAN,tr|A0A3B3IRQ8|A0A3B3IRQ8_HUMAN,tr|A0A3B3ITB8|A0A3B3ITB8_HUMAN,tr|A0A3B3IRI2|A0A3B3IRI2_HUMAN" 6 1119.523 0.82 62878 10549 2 1119.521896 560.7688 CTP synthase 1 OS=Homo sapiens OX=9606 GN=CTPS1 PE=1 SV=2 5.83 2174.8 - 226880 - - - -1.0076 - 1.843 0.497 - 382.4 1 2 0 -0.0011 10 0 0 0 8.68E+06 1.06E+07 - - - 4.4181 0.9999 221125_WJC_METTL3_EV_vs_WT_F05.10552.10552.3 0.0032 13/40 K.KVTQLDLDGPK.E sp|Q13442|HAP28_HUMAN 1 1212.6714 0.52 62879 10552 3 1212.672576 405.2311 28 kDa heat- and acid-stable phosphoprotein OS=Homo sapiens OX=9606 GN=PDAP1 PE=1 SV=1 5.96 2175.2 - 1.23E+06 - - - 0.9673 - 2.508 0.357 - 251.7 1 2 0 0.0012 11 0 0 0 1.21E+07 2.32E+07 - - - 5.132 0.9991 221125_WJC_METTL3_EV_vs_WT_F05.10554.10554.3 4.61E-06 14/44 K.VSSVFK[136.11]DEATVR[166.11].M sp|P46060|RAGP1_HUMAN 1 1354.7212 1.61 62881 10554 3 1354.725288 452.581 Ran GTPase-activating protein 1 OS=Homo sapiens OX=9606 GN=RANGAP1 PE=1 SV=1 6.04 2175.4 - 2.29E+06 - - - 3.0545 - 2.86 0.403 - 382.9 1 2 1 0.0041 12 0 0 0 3.70E+07 2.31E+07 - - - 5.9446 0.9999 221125_WJC_METTL3_EV_vs_WT_F05.10555.10555.2 1.75E-07 13/18 K.HIYYITGETK[136.11].D "sp|Q58FG0|HS905_HUMAN,sp|P07900|HS90A_HUMAN" 2 1231.6328 0.51 62882 10555 2 1231.632831 616.8237 Putative heat shock protein HSP 90-alpha A5 OS=Homo sapiens OX=9606 GN=HSP90AA5P PE=2 SV=1 6.75 2175.5 - 1.16E+06 - - - -0.0065 - 2.543 0.433 - 581 1 2 0 0 10 0 0 0 5.45E+07 1.07E+08 - - - 4.8444 0.9997 221125_WJC_METTL3_EV_vs_WT_F05.10556.10556.2 9.54E-07 22-Sep R.QQPDTEAVLNGK.G "sp|P54105|ICLN_HUMAN,tr|E9PJF4|E9PJF4_HUMAN,tr|J3KN38|J3KN38_HUMAN,tr|E9PMI6|E9PMI6_HUMAN,tr|E9PQ83|E9PQ83_HUMAN" 5 1298.6466 2.41 62883 10556 2 1298.649813 650.3306 Methylosome subunit pICln OS=Homo sapiens OX=9606 GN=CLNS1A PE=1 SV=1 4.37 2175.6 - 749644 - - - 2.4402 - 2.084 0.564 - 307.1 1 2 0 0.0032 12 0 0 0 4.97E+07 2.06E+07 - - - 5.1377 0.9995 221125_WJC_METTL3_EV_vs_WT_F05.10560.10560.2 0.00143 22-Sep K.IMLDSSNLQHQK.L "sp|Q9Y2L1|RRP44_HUMAN,tr|G3V1J5|G3V1J5_HUMAN" 2 1412.7082 1.75 62887 10560 2 1412.708735 707.3614 Exosome complex exonuclease RRP44 OS=Homo sapiens OX=9606 GN=DIS3 PE=1 SV=2 6.74 2176.1 - 118627 - - - 0.3794 - 1.726 0.357 - 232 1 2 0 0.0005 12 0 0 0 4.14E+06 2.37E+06 - - - 3.1137 0.9995 221125_WJC_METTL3_EV_vs_WT_F05.10563.10563.3 0.0027 Nov-36 K.LFKPPQPPAR.M "sp|O15372|EIF3H_HUMAN,tr|B3KS98|B3KS98_HUMAN,tr|A0A087WZK9|A0A087WZK9_HUMAN" 3 1149.6659 1.92 62889 10563 3 1149.666353 384.2292 Eukaryotic translation initiation factor 3 subunit H OS=Homo sapiens OX=9606 GN=EIF3H PE=1 SV=1 11 2176.5 - 3.87E+06 - - - 0.4253 - 2.023 0.293 - 157.2 1 2 0 0.0005 10 0 0 0 1.99E+07 1.04E+07 - - - 3.8642 1 221125_WJC_METTL3_EV_vs_WT_F05.10566.10566.2 1.84E-08 16/18 K.HIYYITGETK.D "sp|Q58FG0|HS905_HUMAN,sp|P07900|HS90A_HUMAN" 2 1223.6186 0.51 62892 10566 2 1223.62007 612.8166 Putative heat shock protein HSP 90-alpha A5 OS=Homo sapiens OX=9606 GN=HSP90AA5P PE=2 SV=1 6.75 2176.7 - 1.22E+06 - - - 1.1695 - 2.839 0.543 - 831.1 1 2 0 0.0014 10 0 0 0 5.46E+07 1.07E+08 - - - 5.9637 0.9995 221125_WJC_METTL3_EV_vs_WT_F05.10567.10567.2 6.01E-05 22-Sep K.LSAMMGAVAEK[136.11]K[136.11].G "sp|Q86U44|MTA70_HUMAN,tr|F5H6D8|F5H6D8_HUMAN,tr|H0YFV6|H0YFV6_HUMAN,tr|B4DTN4|B4DTN4_HUMAN" 4 1250.6698 0.87 62893 10567 2 1250.67196 626.3422 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 8.59 2176.8 - 616250 - - - 1.7551 - 2.084 0.382 - 285.3 1 2 0 0.0022 12 0 0 0 5.56E+06 6.42E+06 - - - 3.7938 0.9997 221125_WJC_METTL3_EV_vs_WT_F05.10569.10569.2 0.323 14-Sep K.DIDIHEVR[166.11].L "sp|Q00839|HNRPU_HUMAN,tr|A0A1W2PQL0|A0A1W2PQL0_HUMAN,tr|A0A1W2PPL4|A0A1W2PPL4_HUMAN,tr|A0A1W2PQ74|A0A1W2PQ74_HUMAN,tr|Q5RI18|Q5RI18_HUMAN,tr|A0A1W2PP35|A0A1W2PP35_HUMAN,tr|A0A1W2PPS1|A0A1W2PPS1_HUMAN,tr|A0A1W2PRZ7|A0A1W2PRZ7_HUMAN,tr|A0A1W2PPH7|A0A1W2PPH7_HUMAN,tr|A0A1W2PP34|A0A1W2PP34_HUMAN,tr|A0A1X7SBS1|A0A1X7SBS1_HUMAN" 11 1005.5119 1.03 62895 10569 2 1005.511719 503.7632 Heterogeneous nuclear ribonucleoprotein U OS=Homo sapiens OX=9606 GN=HNRNPU PE=1 SV=6 4.54 2177 - 452390 - - - -0.1591 - 1.915 0.336 - 335.4 1 2 0 -0.0002 8 0 0 0 1.34E+08 1.29E+08 - - - 3.4822 0.9568 221125_WJC_METTL3_EV_vs_WT_F05.10571.10571.2 0.805 18-Jul K.EETQPPVALK[136.11].K sp|Q8NC51|PAIRB_HUMAN 1 1118.6063 0.61 62897 10571 2 1118.602762 560.3104 Plasminogen activator inhibitor 1 RNA-binding protein OS=Homo sapiens OX=9606 GN=SERBP1 PE=1 SV=2 4.53 2177.3 - 224624 - - - -3.1539 - 1.346 0.112 - 141.9 1 2 0 -0.0035 10 0 0 0 1.45E+06 2.37E+06 - - - 0.6965 0.8126 221125_WJC_METTL3_EV_vs_WT_F05.10572.10572.2 0.00731 26-Aug K.AAVEDSGTTVETIK.L "sp|Q5VTR2|BRE1A_HUMAN,tr|C9JWJ4|C9JWJ4_HUMAN,tr|C9JXC9|C9JXC9_HUMAN,tr|C9J0A5|C9J0A5_HUMAN" 4 1419.7093 1.33 62898 10572 2 1420.712368 710.8619 E3 ubiquitin-protein ligase BRE1A OS=Homo sapiens OX=9606 GN=RNF20 PE=1 SV=2 4.14 2177.4 - 214836 - - - 706.5277 - 1.653 0.14 - 123 1 2 0 1.0031 14 0 0 0 1.91E+06 1.44E+06 - - - 1.0213 0.9999 221125_WJC_METTL3_EV_vs_WT_F05.10573.10573.2 4.83E-05 26-Dec K.AAVEDSGTTVETIK[136.11].L "sp|Q5VTR2|BRE1A_HUMAN,tr|C9JWJ4|C9JWJ4_HUMAN,tr|C9JXC9|C9JXC9_HUMAN,tr|C9J0A5|C9J0A5_HUMAN" 4 1427.7235 1.33 62899 10573 2 1427.724515 714.869 E3 ubiquitin-protein ligase BRE1A OS=Homo sapiens OX=9606 GN=RNF20 PE=1 SV=2 4.14 2177.5 - 170483 - - - 0.7081 - 2.688 0.532 - 618.4 1 2 0 0.001 14 0 0 0 1.91E+06 1.44E+06 - - - 5.4514 0.9998 221125_WJC_METTL3_EV_vs_WT_F05.10576.10576.2 1.04E-05 26-Jul K.VVSTPPSVTEPPEK[136.11].E "sp|Q92667|AKAP1_HUMAN,tr|I3L364|I3L364_HUMAN,tr|I3L2A2|I3L2A2_HUMAN,tr|I3L0K6|I3L0K6_HUMAN,tr|I3L2N7|I3L2N7_HUMAN,tr|I3L3K1|I3L3K1_HUMAN" 6 1473.7806 1.64 62902 10576 2 1473.780126 737.8976 "A-kinase anchor protein 1, mitochondrial OS=Homo sapiens OX=9606 GN=AKAP1 PE=1 SV=1" 4.53 2177.9 - 124229 - - - -0.3386 - 1.722 0.493 - 132.4 1 2 0 -0.0005 14 0 0 0 7.58E+06 4.63E+06 - - - 4.046 0.9996 221125_WJC_METTL3_EV_vs_WT_F05.10580.10580.3 0.00122 Oct-36 K.HIYYITGETK[136.11].D "sp|Q58FG0|HS905_HUMAN,sp|P07900|HS90A_HUMAN" 2 1231.6328 0.58 62905 10580 3 1231.633849 411.5516 Putative heat shock protein HSP 90-alpha A5 OS=Homo sapiens OX=9606 GN=HSP90AA5P PE=2 SV=1 6.75 2178.3 - 2.85E+06 - - - 0.82 - 1.819 0.337 - 168.2 1 2 0 0.001 10 0 0 0 2.90E+07 5.03E+07 - - - 4.0442 0.9999 221125_WJC_METTL3_EV_vs_WT_F05.10581.10581.3 0.000364 14/44 R.HIASGGNGLAWK.L "sp|Q6P3W7|SCYL2_HUMAN,tr|F8VSC5|F8VSC5_HUMAN,tr|A0A0U1RQQ9|A0A0U1RQQ9_HUMAN" 3 1209.6255 1.72 62906 10581 3 1209.626957 404.2158 SCY1-like protein 2 OS=Homo sapiens OX=9606 GN=SCYL2 PE=1 SV=1 8.76 2178.4 - 2.03E+06 - - - 1.2417 - 2.602 0.409 - 320.5 1 2 0 0.0015 12 0 0 0 3.45E+07 2.01E+07 - - - 5.7502 0.9999 221125_WJC_METTL3_EV_vs_WT_F05.10583.10583.3 0.000571 Dec-40 R.LNQLKPGLQYK.L sp|Q12906|ILF3_HUMAN 1 1300.7503 1.11 62908 10583 3 1300.750361 434.5907 Interleukin enhancer-binding factor 3 OS=Homo sapiens OX=9606 GN=ILF3 PE=1 SV=3 9.7 2178.6 - 854480 - - - 0.03 - 2.321 0.411 - 191.6 1 2 0 0 11 0 0 0 2.00E+08 1.81E+08 - - - 5.5142 0.9997 221125_WJC_METTL3_EV_vs_WT_F05.10584.10584.2 0.0013 22-Nov R.HIASGGNGLAWK[136.11].L "sp|Q6P3W7|SCYL2_HUMAN,tr|F8VSC5|F8VSC5_HUMAN,tr|A0A0U1RQQ9|A0A0U1RQQ9_HUMAN" 3 1217.6397 2.03 62909 10584 2 1217.64008 609.8271 SCY1-like protein 2 OS=Homo sapiens OX=9606 GN=SCYL2 PE=1 SV=1 8.76 2178.7 - 832813 - - - 0.349 - 2.051 0.359 - 268.6 1 2 0 0.0004 12 0 0 0 2.07E+07 1.02E+07 - - - 3.5825 0.9995 221125_WJC_METTL3_EV_vs_WT_F05.10586.10586.2 0.00207 22-Oct K.GSFSDTGLGDGK.M "sp|Q9Y2W1|TR150_HUMAN,tr|A0A3B3ITZ9|A0A3B3ITZ9_HUMAN" 2 1139.5095 6.84 62911 10586 2 1139.507998 570.762 Thyroid hormone receptor-associated protein 3 OS=Homo sapiens OX=9606 GN=THRAP3 PE=1 SV=2 4.21 2178.9 - 518197 - - - -1.3023 - 1.57 0.415 - 162.4 1 2 0 -0.0015 12 0 0 0 8.00E+06 1.17E+06 - - - 3.2926 0.9681 221125_WJC_METTL3_EV_vs_WT_F05.10587.10587.3 3.45E-05 14/44 L.IVSVDETIK[136.11]NPR[166.11].S sp|Q99832|TCPH_HUMAN 1 1387.779 0.27 62912 10587 3 1387.781987 463.6003 T-complex protein 1 subunit eta OS=Homo sapiens OX=9606 GN=CCT7 PE=1 SV=2 6.07 2179 - 349991 - - - 2.1531 - 2.484 0.482 - 318.3 1 1 1 0.003 12 0 0 0 3.59E+06 1.32E+07 - - - 6.435 0.9864 221125_WJC_METTL3_EV_vs_WT_F05.10590.10590.2 3.65E-06 26-Jun K.ELNNTC[160.03]EPVVTQPK[136.11].P "sp|Q92598|HS105_HUMAN,tr|Q5TBM3|Q5TBM3_HUMAN,tr|A0A0A0MSM0|A0A0A0MSM0_HUMAN" 3 1635.8018 0.001 62915 10590 2 1635.80095 818.9082 Heat shock protein 105 kDa OS=Homo sapiens OX=9606 GN=HSPH1 PE=1 SV=1 4.53 2179.4 - 97873.1 - - - -0.5025 - 1.445 0.538 - 85.8 1 1 0 -0.0008 14 0 0 0 0.00E+00 7.12E+05 - - - 3.9382 0.9999 221125_WJC_METTL3_EV_vs_WT_F05.10593.10593.3 0.00357 Nov-40 R.ELEAELEDER[166.11]K[136.11].Q sp|P35580|MYH10_HUMAN 1 1377.6743 1.35 62917 10593 3 1377.673756 460.232 Myosin-10 OS=Homo sapiens OX=9606 GN=MYH10 PE=1 SV=3 4.14 2179.8 - 2.14E+06 - - - -0.3651 - 2.24 0.429 - 189 1 2 0 -0.0005 11 0 0 0 3.07E+07 2.28E+07 - - - 5.6138 0.9996 221125_WJC_METTL3_EV_vs_WT_F05.10595.10595.2 0.128 14-Sep K.DIDIHEVR.L "sp|Q00839|HNRPU_HUMAN,tr|A0A1W2PQL0|A0A1W2PQL0_HUMAN,tr|A0A1W2PPL4|A0A1W2PPL4_HUMAN,tr|A0A1W2PQ74|A0A1W2PQ74_HUMAN,tr|Q5RI18|Q5RI18_HUMAN,tr|A0A1W2PP35|A0A1W2PP35_HUMAN,tr|A0A1W2PPS1|A0A1W2PPS1_HUMAN,tr|A0A1W2PRZ7|A0A1W2PRZ7_HUMAN,tr|A0A1W2PPH7|A0A1W2PPH7_HUMAN,tr|A0A1W2PP34|A0A1W2PP34_HUMAN,tr|A0A1X7SBS1|A0A1X7SBS1_HUMAN" 11 995.5036 1.03 62918 10595 2 995.503446 498.7591 Heterogeneous nuclear ribonucleoprotein U OS=Homo sapiens OX=9606 GN=HNRNPU PE=1 SV=6 4.54 2180 - 4.58E+06 - - - -0.1637 - 1.699 0.339 - 330.8 1 2 0 -0.0002 8 0 0 0 1.34E+08 1.29E+08 - - - 3.1434 0.9996 221125_WJC_METTL3_EV_vs_WT_F05.10596.10596.3 0.0212 Oct-40 R.LNQLK[136.11]PGLQYK[136.11].L sp|Q12906|ILF3_HUMAN 1 1316.7787 1.11 62919 10596 3 1316.778644 439.9335 Interleukin enhancer-binding factor 3 OS=Homo sapiens OX=9606 GN=ILF3 PE=1 SV=3 9.7 2180 - 4.54E+06 - - - -0.0592 - 1.92 0.322 - 138.6 1 2 0 -0.0001 11 0 0 0 2.00E+08 1.81E+08 - - - 3.9831 0.9998 221125_WJC_METTL3_EV_vs_WT_F05.10597.10597.3 2.42E-05 Dec-36 K.HIYYITGETK.D "sp|Q58FG0|HS905_HUMAN,sp|P07900|HS90A_HUMAN" 2 1223.6186 0.58 62920 10597 3 1223.618443 408.8802 Putative heat shock protein HSP 90-alpha A5 OS=Homo sapiens OX=9606 GN=HSP90AA5P PE=2 SV=1 6.75 2180.1 - 2.67E+06 - - - -0.1602 - 1.936 0.363 - 241.1 1 2 0 -0.0002 10 0 0 0 2.90E+07 5.03E+07 - - - 4.5163 0.9992 221125_WJC_METTL3_EV_vs_WT_F05.10598.10598.3 0.00512 Nov-40 R.QSFVPVRPGPR.Q sp|P22735|TGM1_HUMAN 1 1238.6884 19.46 62921 10598 3 1238.688403 413.9034 Protein-glutamine gamma-glutamyltransferase K OS=Homo sapiens OX=9606 GN=TGM1 PE=1 SV=4 12 2180.1 - 2.22E+06 - - - 0.0105 - 1.781 0.298 - 147.7 1 2 0 0 11 0 0 0 4.92E+07 2.53E+06 - - - 3.5021 0.9976 221125_WJC_METTL3_EV_vs_WT_F05.10599.10599.3 3.93E-07 13/52 Y.EIDAC[160.03]MDSEAPGSK[136.11].D "sp|Q86U44|MTA70_HUMAN,tr|H0YFV6|H0YFV6_HUMAN" 2 1516.6265 0 62922 10599 3 1516.626812 506.5494 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 3.92 2180.2 - 1.56E+06 - - - 0.1998 - 2.281 0.55 - 204.9 1 1 0 0.0003 14 0 0 0 4.55E+04 1.42E+07 - - - 6.8633 0.9994 221125_WJC_METTL3_EV_vs_WT_F05.10600.10600.3 0.0126 Oct-32 K.VWYHVC[160.03]SSR.G "sp|Q92499|DDX1_HUMAN,tr|A0A7I2V2M5|A0A7I2V2M5_HUMAN,tr|A0A087X2G1|A0A087X2G1_HUMAN,tr|A0A7I2V430|A0A7I2V430_HUMAN,tr|A0A7I2V4F0|A0A7I2V4F0_HUMAN,tr|A0A087WZ71|A0A087WZ71_HUMAN,tr|A0A7I2YQ77|A0A7I2YQ77_HUMAN" 7 1192.5448 1.21 62923 10600 3 1192.545433 398.5222 ATP-dependent RNA helicase DDX1 OS=Homo sapiens OX=9606 GN=DDX1 PE=1 SV=2 8.2 2180.3 - 1.26E+06 - - - 0.5627 - 1.886 0.292 - 199.7 1 2 0 0.0007 9 0 0 0 1.35E+07 1.11E+07 - - - 3.7075 0.9974 221125_WJC_METTL3_EV_vs_WT_F05.10602.10602.3 0.0867 Nov-44 R.LLTVSSHNLESK.S sp|Q6NUJ1|SAPL1_HUMAN 1 1326.7143 2 62925 10602 3 1326.716624 443.2454 Proactivator polypeptide-like 1 OS=Homo sapiens OX=9606 GN=PSAPL1 PE=2 SV=2 6.75 2180.6 - 533925 - - - 1.7291 - 1.866 0.243 - 125.1 1 2 0 0.0023 12 0 0 0 5.14E+06 2.57E+06 - - - 2.9776 0.9902 221125_WJC_METTL3_EV_vs_WT_F05.10605.10605.2 0.000349 24-Oct Q.GGSGYDYSYAGGR.G "sp|P61978|HNRPK_HUMAN,tr|S4R359|S4R359_HUMAN,tr|Q5T6W2|Q5T6W2_HUMAN" 3 1308.5371 0.99 62928 10605 2 1308.536953 655.2758 Heterogeneous nuclear ribonucleoprotein K OS=Homo sapiens OX=9606 GN=HNRNPK PE=1 SV=1 5.83 2180.9 - 534606 - - - -0.1078 - 1.617 0.55 - 280 1 1 0 -0.0001 13 0 0 0 4.54E+06 4.59E+06 - - - 4.3367 0.9906 221125_WJC_METTL3_EV_vs_WT_F05.10606.10606.3 0.000249 16/76 A.AAPVAAATTAAPAAAAAPAK.V "sp|P05388|RLA0_HUMAN,tr|F8VWS0|F8VWS0_HUMAN,tr|F8W1K8|F8W1K8_HUMAN" 3 1661.9101 1.62 62929 10606 3 1661.912832 554.9773 60S acidic ribosomal protein P0 OS=Homo sapiens OX=9606 GN=RPLP0 PE=1 SV=1 8.8 2181.1 - 299352 - - - 1.6619 - 2.881 0.417 - 351.4 1 1 0 0.0028 20 0 0 0 4.17E+06 2.57E+06 - - - 5.7554 0.9938 221125_WJC_METTL3_EV_vs_WT_F05.10607.10607.2 0.0986 22-Jul K.GSFSDTGLGDGK[136.11].M "sp|Q9Y2W1|TR150_HUMAN,tr|A0A3B3ITZ9|A0A3B3ITZ9_HUMAN" 2 1147.5237 4.22 62930 10607 2 1147.523722 574.7691 Thyroid hormone receptor-associated protein 3 OS=Homo sapiens OX=9606 GN=THRAP3 PE=1 SV=2 4.21 2181.2 - 287192 - - - 0.0349 - 1.054 0.24 - 84.9 1 2 0 0 12 0 0 0 1.04E+07 2.46E+06 - - - 0.952 0.9843 221125_WJC_METTL3_EV_vs_WT_F05.10608.10608.3 0.000753 14/76 A.AAPVAAATTAAPAAAAAPAK[136.11].V "sp|P05388|RLA0_HUMAN,tr|F8VWS0|F8VWS0_HUMAN,tr|F8W1K8|F8W1K8_HUMAN" 3 1669.9243 1.62 62931 10608 3 1669.921618 557.6487 60S acidic ribosomal protein P0 OS=Homo sapiens OX=9606 GN=RPLP0 PE=1 SV=1 8.8 2181.3 - 273284 - - - -1.5881 - 2.825 0.362 - 207.9 1 1 0 -0.0027 20 0 0 0 4.17E+06 2.57E+06 - - - 5.0947 1 221125_WJC_METTL3_EV_vs_WT_F05.10610.10610.2 6.66E-07 Dec-38 A.AAPVAAATTAAPAAAAAPAK.V "sp|P05388|RLA0_HUMAN,tr|F8VWS0|F8VWS0_HUMAN,tr|F8W1K8|F8W1K8_HUMAN" 3 1661.9101 1.44 62933 10610 2 1661.908072 831.9623 60S acidic ribosomal protein P0 OS=Homo sapiens OX=9606 GN=RPLP0 PE=1 SV=1 8.8 2181.6 - 152422 - - - -1.2022 - 2.921 0.582 - 380.3 1 1 0 -0.002 20 0 0 0 1.73E+06 1.20E+06 - - - 5.9744 1 221125_WJC_METTL3_EV_vs_WT_F05.10612.10612.2 2.68E-07 13/20 K.FAEALGSTEAK.A "sp|P78347|GTF2I_HUMAN,tr|A0A494C0Q7|A0A494C0Q7_HUMAN,tr|A0A494C1K3|A0A494C1K3_HUMAN" 3 1122.5557 1.14 62935 10612 2 1122.55519 562.2851 General transcription factor II-I OS=Homo sapiens OX=9606 GN=GTF2I PE=1 SV=2 4.53 2181.9 - 136824 - - - -0.4579 - 2.623 0.577 - 524.3 1 2 0 -0.0005 11 0 0 0 3.86E+06 3.40E+06 - - - 5.9113 1 221125_WJC_METTL3_EV_vs_WT_F05.10617.10617.3 0.00363 13/44 K.SVHFPGQAVGTR.R "sp|Q06210|GFPT1_HUMAN,tr|A0A6I8PRN4|A0A6I8PRN4_HUMAN,tr|A0A6I8PTT9|A0A6I8PTT9_HUMAN" 3 1254.6469 1.32 62938 10617 3 1254.646039 419.2229 Glutamine--fructose-6-phosphate aminotransferase [isomerizing] 1 OS=Homo sapiens OX=9606 GN=GFPT1 PE=1 SV=3 9.49 2182.3 - 4.59E+06 - - - -0.7014 - 2.517 0.455 - 284.9 1 2 0 -0.0009 12 0 0 0 5.45E+07 4.13E+07 - - - 6.1712 0.9993 221125_WJC_METTL3_EV_vs_WT_F05.10619.10619.2 0.0758 20-Sep R.LNQLK[136.11]PGLQYK[136.11].L sp|Q12906|ILF3_HUMAN 1 1316.7787 1.2 62940 10619 2 1316.779297 659.3966 Interleukin enhancer-binding factor 3 OS=Homo sapiens OX=9606 GN=ILF3 PE=1 SV=3 9.7 2182.6 - 747181 - - - 0.4367 - 2.002 0.255 - 297.8 1 2 0 0.0006 11 0 0 0 1.76E+07 1.46E+07 - - - 2.8021 0.9958 221125_WJC_METTL3_EV_vs_WT_F05.10620.10620.2 0.000636 18-Oct K.ESEAVEWQQK[136.11].A sp|P26038|MOES_HUMAN 1 1240.5815 0.76 62941 10620 2 1240.575881 621.298 Moesin OS=Homo sapiens OX=9606 GN=MSN PE=1 SV=3 4.25 2182.7 - 711584 - - - -4.5543 - 1.724 0.407 - 407.9 1 2 0 -0.0057 10 0 0 0 3.20E+06 4.20E+06 - - - 3.5656 0.9995 221125_WJC_METTL3_EV_vs_WT_F05.10621.10621.2 0.00074 22-Sep K.SVHFPGQAVGTR.R "sp|Q06210|GFPT1_HUMAN,tr|A0A6I8PRN4|A0A6I8PRN4_HUMAN,tr|A0A6I8PTT9|A0A6I8PTT9_HUMAN" 3 1254.6469 5.62 62942 10621 2 1254.646734 628.3307 Glutamine--fructose-6-phosphate aminotransferase [isomerizing] 1 OS=Homo sapiens OX=9606 GN=GFPT1 PE=1 SV=3 9.49 2182.8 - 421342 - - - -0.1475 - 1.709 0.34 - 225.2 1 2 0 -0.0002 12 0 0 0 5.50E+06 9.79E+05 - - - 2.9622 0.9719 221125_WJC_METTL3_EV_vs_WT_F05.10622.10622.2 0.412 18-Aug R.K[136.11]SGVGNVFIK[136.11].N "sp|Q13310|PABP4_HUMAN,sp|Q5JQF8|PAP1M_HUMAN,tr|A0A7I2V5W9|A0A7I2V5W9_HUMAN,tr|B1ANR0|B1ANR0_HUMAN,tr|A0A7I2V4L7|A0A7I2V4L7_HUMAN,tr|B1ANR1|B1ANR1_HUMAN,tr|A0A7I2V598|A0A7I2V598_HUMAN,tr|H0YEQ8|H0YEQ8_HUMAN" 8 1063.6361 1.57 62943 10622 2 1063.635265 532.8253 Polyadenylate-binding protein 4 OS=Homo sapiens OX=9606 GN=PABPC4 PE=1 SV=1 10 2182.9 - 366728 - - - -0.7662 - 1.466 0.003 - 174.9 2 2 0 -0.0008 10 0 0 0 9.56E+06 6.08E+06 - - - -0.0038 0.9996 221125_WJC_METTL3_EV_vs_WT_F05.10623.10623.2 0.000282 26-Aug K.VVSTPPSVTEPPEK.E "sp|Q92667|AKAP1_HUMAN,tr|I3L364|I3L364_HUMAN,tr|I3L2A2|I3L2A2_HUMAN,tr|I3L0K6|I3L0K6_HUMAN,tr|I3L2N7|I3L2N7_HUMAN,tr|I3L3K1|I3L3K1_HUMAN" 6 1465.7664 1.56 62944 10623 2 1465.767758 733.8905 "A-kinase anchor protein 1, mitochondrial OS=Homo sapiens OX=9606 GN=AKAP1 PE=1 SV=1" 4.53 2183.1 - 258076 - - - 0.9094 - 1.58 0.454 - 153.3 1 2 0 0.0013 14 0 0 0 6.81E+06 4.36E+06 - - - 3.5417 0.9955 221125_WJC_METTL3_EV_vs_WT_F05.10624.10624.2 0.00114 16-Aug K.VDK[136.11]LDVNIK[136.11].S "sp|O95721|SNP29_HUMAN,tr|C9JAF7|C9JAF7_HUMAN" 2 1058.6307 2.4 62945 10624 2 1058.631481 530.3226 Synaptosomal-associated protein 29 OS=Homo sapiens OX=9606 GN=SNAP29 PE=1 SV=1 5.93 2183.2 - 236835 - - - 0.7755 - 1.766 0.375 - 176 1 2 1 0.0008 9 0 0 0 1.10E+07 4.58E+06 - - - 3.4558 0.9867 221125_WJC_METTL3_EV_vs_WT_F05.10626.10626.2 0.000172 Nov-38 A.AAPVAAATTAAPAAAAAPAK[136.11].V "sp|P05388|RLA0_HUMAN,tr|F8VWS0|F8VWS0_HUMAN,tr|F8W1K8|F8W1K8_HUMAN" 3 1669.9243 1.44 62947 10626 2 1669.927807 835.9694 60S acidic ribosomal protein P0 OS=Homo sapiens OX=9606 GN=RPLP0 PE=1 SV=1 8.8 2183.5 - 131407 - - - 2.1181 - 2.485 0.569 - 351.9 1 1 0 0.0035 20 0 0 0 1.73E+06 1.20E+06 - - - 5.4805 0.9997 221125_WJC_METTL3_EV_vs_WT_F05.10628.10628.3 0.319 Dec-44 K.IMLDSSNLQHQK[136.11].L "sp|Q9Y2L1|RRP44_HUMAN,tr|G3V1J5|G3V1J5_HUMAN" 2 1420.7224 1.45 62948 10628 3 1420.723145 474.5814 Exosome complex exonuclease RRP44 OS=Homo sapiens OX=9606 GN=DIS3 PE=1 SV=2 6.74 2183.7 - 1.32E+06 - - - 0.5251 - 2.203 0.314 - 164.3 1 2 0 0.0007 12 0 0 0 4.89E+07 3.38E+07 - - - 4.2298 0.9977 221125_WJC_METTL3_EV_vs_WT_F05.10636.10636.2 5.98E-06 18-Nov K.NNTQVLINC[160.03]R[166.11].N "sp|P62316|SMD2_HUMAN,tr|K7ERG4|K7ERG4_HUMAN" 2 1240.6222 1.29 62955 10636 2 1240.628425 621.3184 Small nuclear ribonucleoprotein Sm D2 OS=Homo sapiens OX=9606 GN=SNRPD2 PE=1 SV=1 8.25 2184.5 - 489272 - - - 5.0378 - 2.489 0.459 - 593.7 1 2 0 0.0063 10 0 0 0 5.09E+07 3.95E+07 - - - 4.9745 0.9934 221125_WJC_METTL3_EV_vs_WT_F05.10637.10637.2 0.0523 20-May K.EYDELAETQGK[136.11].L "sp|O60341|KDM1A_HUMAN,tr|R4GMQ1|R4GMQ1_HUMAN" 2 1289.5867 1.66 62956 10637 2 1289.582716 645.8006 Lysine-specific histone demethylase 1A OS=Homo sapiens OX=9606 GN=KDM1A PE=1 SV=2 4 2184.6 - 158566 - - - -3.0708 - 1.154 0.358 - 87.9 1 2 0 -0.004 11 0 0 0 2.92E+06 1.76E+06 - - - 2.0714 0.9981 221125_WJC_METTL3_EV_vs_WT_F05.10644.10644.2 0.0061 16-Dec K.VDKLDVNIK.S "sp|O95721|SNP29_HUMAN,tr|C9JAF7|C9JAF7_HUMAN" 2 1042.6023 2.37 62961 10644 2 1042.603219 522.3084 Synaptosomal-associated protein 29 OS=Homo sapiens OX=9606 GN=SNAP29 PE=1 SV=1 5.93 2185.5 - 1.05E+06 - - - 0.9198 - 2.288 0.441 - 493.5 1 2 1 0.001 9 0 0 0 1.08E+07 4.58E+06 - - - 4.6924 0.9997 221125_WJC_METTL3_EV_vs_WT_F05.10646.10646.2 0.000255 20-Sep R.SNPSIQATLNK.T sp|Q6UUV7|CRTC3_HUMAN 1 1171.6197 2.04 62963 10646 2 1171.620966 586.8171 CREB-regulated transcription coactivator 3 OS=Homo sapiens OX=9606 GN=CRTC3 PE=1 SV=2 8.47 2185.7 - 448586 - - - 1.0797 - 1.972 0.43 - 224.8 1 2 0 0.0013 11 0 0 0 1.36E+07 6.67E+06 - - - 4.0536 0.9999 221125_WJC_METTL3_EV_vs_WT_F05.10649.10649.2 0.000112 26-Nov K.TDELPAAAPADSAR[166.11].E "tr|A0A494C0R8|A0A494C0R8_HUMAN,tr|I3L2B0|I3L2B0_HUMAN" 2 1393.6713 0.94 62966 10649 2 1393.670976 697.8429 Clustered mitochondria protein homolog OS=Homo sapiens OX=9606 GN=CLUH PE=1 SV=1 4.03 2186.1 - 256056 - - - -0.2275 - 2.532 0.438 - 366.8 1 2 0 -0.0003 14 0 0 0 2.65E+06 2.81E+06 - - - 4.6073 0.9998 221125_WJC_METTL3_EV_vs_WT_F05.10650.10650.2 0.00235 22-Jul K.DMNQFGEGEQAK[136.11].L "sp|Q00341|VIGLN_HUMAN,tr|C9JHZ8|C9JHZ8_HUMAN,tr|C9JZI8|C9JZI8_HUMAN,tr|A0A024R4E5|A0A024R4E5_HUMAN,tr|C9JIZ1|C9JIZ1_HUMAN,tr|C9JES8|C9JES8_HUMAN,tr|C9J5E5|C9J5E5_HUMAN,tr|C9JHS7|C9JHS7_HUMAN" 8 1360.5809 1.74 62967 10650 2 1360.581111 681.2977 Vigilin OS=Homo sapiens OX=9606 GN=HDLBP PE=1 SV=2 4.14 2186.2 - 144144 - - - 0.1698 - 1.328 0.55 - 166.7 1 2 0 0.0002 12 0 0 0 2.53E+06 1.45E+06 - - - 3.8496 0.9999 221125_WJC_METTL3_EV_vs_WT_F05.10652.10652.2 0.14 13/18 R.YPDGIISK[136.11]PK[136.11].N sp|Q86U44|MTA70_HUMAN 1 1132.6463 0.001 62968 10652 2 1132.644913 567.3304 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 8.5 2186.5 - 741597 - - - -1.2334 - 2.297 0.52 - 644.7 1 2 0 -0.0014 10 0 0 0 0.00E+00 1.59E+07 - - - 5.2025 0.9998 221125_WJC_METTL3_EV_vs_WT_F05.10656.10656.3 0.0123 17/44 K.GIVEFSGKPAAR.K "sp|Q15233|NONO_HUMAN,tr|A0A7I2V535|A0A7I2V535_HUMAN,tr|A0A7I2V4N2|A0A7I2V4N2_HUMAN,tr|A0A7I2V464|A0A7I2V464_HUMAN,tr|A0A7P0MRW0|A0A7P0MRW0_HUMAN,tr|H7C367|H7C367_HUMAN,tr|C9IZL7|C9IZL7_HUMAN,tr|A0A7I2V4J2|A0A7I2V4J2_HUMAN,tr|A0A7I2V5Y7|A0A7I2V5Y7_HUMAN" 9 1230.6721 0.75 62971 10656 3 1230.673489 411.2313 Non-POU domain-containing octamer-binding protein OS=Homo sapiens OX=9606 GN=NONO PE=1 SV=4 8.75 2186.8 - 2.55E+06 - - - 1.1522 - 2.678 0.33 - 379.7 1 2 0 0.0014 12 0 0 0 1.41E+08 1.88E+08 - - - 4.9493 0.9391 221125_WJC_METTL3_EV_vs_WT_F05.10657.10657.3 0.501 Aug-40 K.TLNQQLTNHIR[166.11].E "sp|P50570|DYN2_HUMAN,tr|K7EMQ3|K7EMQ3_HUMAN" 2 1346.7294 1.03 62972 10657 3 1346.729243 449.9171 Dynamin-2 OS=Homo sapiens OX=9606 GN=DNM2 PE=1 SV=2 9.44 2186.8 - 1.01E+06 - - - -0.1292 - 1.523 0.11 - 52.8 3 2 0 -0.0002 11 0 0 0 1.62E+07 1.58E+07 - - - 0.7406 0.9997 221125_WJC_METTL3_EV_vs_WT_F05.10658.10658.2 0.000154 20-Oct K.GESQTDIEITR[166.11].E "sp|P49368|TCPG_HUMAN,tr|B4DUR8|B4DUR8_HUMAN" 2 1257.6076 0.1 62973 10658 2 1257.606898 629.8111 T-complex protein 1 subunit gamma OS=Homo sapiens OX=9606 GN=CCT3 PE=1 SV=4 4.14 2187 - 666600 - - - -0.5821 - 2.18 0.329 - 458.1 1 2 0 -0.0007 11 0 0 0 2.49E+06 2.40E+07 - - - 3.579 0.9021 221125_WJC_METTL3_EV_vs_WT_F05.10659.10659.2 0.00151 18-Nov L.NQLKPGLQYK.L sp|Q12906|ILF3_HUMAN 1 1187.6663 1.2 62974 10659 2 1187.669077 594.8404 Interleukin enhancer-binding factor 3 OS=Homo sapiens OX=9606 GN=ILF3 PE=1 SV=3 9.7 2187.1 - 385625 - - - 2.3736 - 2.108 0.231 - 491.7 1 1 0 0.0028 10 0 0 0 5.21E+06 4.36E+06 - - - 2.8279 1 221125_WJC_METTL3_EV_vs_WT_F05.10660.10660.3 2.47E-06 Nov-40 R.YHGYQLVDGGR[166.11].F sp|Q86TJ2|TAD2B_HUMAN 1 1273.6079 1.42 62975 10660 3 1273.606587 425.5432 Transcriptional adapter 2-beta OS=Homo sapiens OX=9606 GN=TADA2B PE=1 SV=2 6.74 2187.2 - 278874 - - - -1.0349 - 2.322 0.461 - 255.7 1 2 0 -0.0013 11 0 0 0 8.98E+06 6.31E+06 - - - 6.0725 0.9996 221125_WJC_METTL3_EV_vs_WT_F05.10661.10661.2 0.0132 18-Aug R.FVVQNVSAQK[136.11].D "sp|Q92598|HS105_HUMAN,tr|A0A0A0MSM0|A0A0A0MSM0_HUMAN" 2 1126.6226 0.15 62976 10661 2 1126.623582 564.3186 Heat shock protein 105 kDa OS=Homo sapiens OX=9606 GN=HSPH1 PE=1 SV=1 8.75 2187.4 - 234436 - - - 0.8645 - 1.613 0.408 - 192.9 1 2 0 0.001 10 0 0 0 1.28E+06 8.36E+06 - - - 3.3887 0.9992 221125_WJC_METTL3_EV_vs_WT_F05.10668.10668.2 0.00274 12-May K.DNNLLGR[166.11].F "sp|P0DMV8|HS71A_HUMAN,sp|P34931|HS71L_HUMAN,sp|P0DMV9|HS71B_HUMAN,sp|P17066|HSP76_HUMAN,tr|Q53FA3|Q53FA3_HUMAN,tr|V9GZ37|V9GZ37_HUMAN,tr|A0A0G2JIW1|A0A0G2JIW1_HUMAN" 7 810.4223 0.15 62981 10668 2 810.422871 406.2184 Heat shock 70 kDa protein 1A OS=Homo sapiens OX=9606 GN=HSPA1A PE=1 SV=1 5.84 2188.2 - 3.57E+06 - - - 0.6601 - 1.397 0.352 - 177.6 1 2 0 0.0005 7 0 0 0 1.01E+07 6.59E+07 - - - 2.7 0.9838 221125_WJC_METTL3_EV_vs_WT_F05.10671.10671.2 0.00799 18-Oct L.VEFSGKPAAR.K "sp|Q15233|NONO_HUMAN,tr|A0A7I2V535|A0A7I2V535_HUMAN,tr|A0A7I2V4N2|A0A7I2V4N2_HUMAN,tr|A0A7I2V464|A0A7I2V464_HUMAN,tr|A0A7P0MRW0|A0A7P0MRW0_HUMAN,tr|H7C367|H7C367_HUMAN,tr|C9IZL7|C9IZL7_HUMAN,tr|A0A7I2V4J2|A0A7I2V4J2_HUMAN,tr|A0A7I2V5Y7|A0A7I2V5Y7_HUMAN" 9 1060.5665 0.87 62984 10671 2 1060.567465 531.2905 Non-POU domain-containing octamer-binding protein OS=Homo sapiens OX=9606 GN=NONO PE=1 SV=4 8.72 2188.5 - 840883 - - - 0.8693 - 1.781 0.448 - 432.8 1 1 0 0.0009 10 0 0 0 2.27E+07 2.61E+07 - - - 3.9607 0.9938 221125_WJC_METTL3_EV_vs_WT_F05.10672.10672.3 0.221 Aug-40 K.SPLAQMEEER[166.11]R[166.11].E "sp|Q16181|SEPT7_HUMAN,tr|E7EPK1|E7EPK1_HUMAN,tr|G3V1Q4|G3V1Q4_HUMAN,tr|E7ES33|E7ES33_HUMAN,tr|A0A0U1RRM2|A0A0U1RRM2_HUMAN" 5 1364.6621 0.98 62985 10672 3 1364.660943 455.8947 Septin-7 OS=Homo sapiens OX=9606 GN=SEPTIN7 PE=1 SV=2 4.78 2188.6 - 433521 - - - -0.8764 - 1.586 0.202 - 76 1 2 0 -0.0012 11 0 0 0 9.90E+06 1.01E+07 - - - 2.102 0.9941 221125_WJC_METTL3_EV_vs_WT_F05.10673.10673.3 4.51E-08 14/52 R.PVVIC[160.03]DKEDTETIK.N "sp|Q06210|GFPT1_HUMAN,tr|A0A6I8PRN4|A0A6I8PRN4_HUMAN,tr|A0A6I8PTT9|A0A6I8PTT9_HUMAN" 3 1645.8233 1.38 62986 10673 3 1645.82308 549.615 Glutamine--fructose-6-phosphate aminotransferase [isomerizing] 1 OS=Homo sapiens OX=9606 GN=GFPT1 PE=1 SV=3 4.32 2188.7 - 324059 - - - -0.127 - 2.556 0.614 - 153.6 1 1 1 -0.0002 14 0 0 0 8.51E+06 6.16E+06 - - - 7.8794 0.9951 221125_WJC_METTL3_EV_vs_WT_F05.10674.10674.3 5.21E-08 17/52 R.PVVIC[160.03]DK[136.11]EDTETIK[136.11].N "sp|Q06210|GFPT1_HUMAN,tr|A0A6I8PRN4|A0A6I8PRN4_HUMAN,tr|A0A6I8PTT9|A0A6I8PTT9_HUMAN" 3 1661.8517 1.38 62987 10674 3 1661.853129 554.9578 Glutamine--fructose-6-phosphate aminotransferase [isomerizing] 1 OS=Homo sapiens OX=9606 GN=GFPT1 PE=1 SV=3 4.32 2188.9 - 297176 - - - 0.8665 - 3.171 0.606 - 376.8 1 1 1 0.0014 14 0 0 0 8.51E+06 6.16E+06 - - - 8.3628 0.8965 221125_WJC_METTL3_EV_vs_WT_F05.10681.10681.2 0.00908 16-Jul V.EFSGK[136.11]PAAR[166.11].K "sp|Q15233|NONO_HUMAN,tr|A0A7I2V535|A0A7I2V535_HUMAN,tr|A0A7I2V4N2|A0A7I2V4N2_HUMAN,tr|A0A7I2V464|A0A7I2V464_HUMAN,tr|A0A7P0MRW0|A0A7P0MRW0_HUMAN,tr|H7C367|H7C367_HUMAN,tr|C9IZL7|C9IZL7_HUMAN,tr|A0A7I2V4J2|A0A7I2V4J2_HUMAN,tr|A0A7I2V5Y7|A0A7I2V5Y7_HUMAN" 9 979.5206 0.77 62992 10681 2 979.521995 490.7676 Non-POU domain-containing octamer-binding protein OS=Homo sapiens OX=9606 GN=NONO PE=1 SV=4 8.85 2189.7 - 483758 - - - 1.4242 - 1.371 0.309 - 177.2 1 1 0 0.0014 9 0 0 0 5.91E+06 7.72E+06 - - - 2.2357 1 221125_WJC_METTL3_EV_vs_WT_F05.10682.10682.3 1.10E-05 15/44 K.SLEIQKPAVAPR.H sp|P48634|PRC2A_HUMAN 1 1307.7561 1.18 62993 10682 3 1307.757369 436.926 Protein PRRC2A OS=Homo sapiens OX=9606 GN=PRRC2A PE=1 SV=3 8.46 2189.8 - 803814 - - - 0.9436 - 3.243 0.487 - 257.8 1 2 0 0.0012 12 0 0 0 9.82E+07 8.35E+07 - - - 7.2303 0.997 221125_WJC_METTL3_EV_vs_WT_F05.10683.10683.2 0.184 18-Sep R.KSGVGNVFIK.N "sp|Q13310|PABP4_HUMAN,sp|Q5JQF8|PAP1M_HUMAN,tr|A0A7I2V5W9|A0A7I2V5W9_HUMAN,tr|B1ANR0|B1ANR0_HUMAN,tr|A0A7I2V4L7|A0A7I2V4L7_HUMAN,tr|B1ANR1|B1ANR1_HUMAN,tr|A0A7I2V598|A0A7I2V598_HUMAN,tr|H0YEQ8|H0YEQ8_HUMAN" 8 1047.6077 1.68 62994 10683 2 1047.608648 524.8111 Polyadenylate-binding protein 4 OS=Homo sapiens OX=9606 GN=PABPC4 PE=1 SV=1 10 2189.9 - 427877 - - - 0.924 - 1.417 0.225 - 195.9 1 2 0 0.001 10 0 0 0 1.02E+07 6.08E+06 - - - 1.6754 0.9999 221125_WJC_METTL3_EV_vs_WT_F05.10691.10691.2 0.000889 22-Oct R.DLMAC[160.03]AQTGSGK.T "sp|O00571|DDX3X_HUMAN,sp|O15523|DDX3Y_HUMAN,sp|Q9NQI0|DDX4_HUMAN,tr|A0A2R8YFR4|A0A2R8YFR4_HUMAN,tr|A0A2R8YCW1|A0A2R8YCW1_HUMAN,tr|A0A2R8YDH3|A0A2R8YDH3_HUMAN,tr|A0A2R8YDT5|A0A2R8YDT5_HUMAN,tr|A0A2R8Y645|A0A2R8Y645_HUMAN,tr|A0A2R8YF78|A0A2R8YF78_HUMAN,tr|D6RCM4|D6RCM4_HUMAN,tr|A0A0D9SFB3|A0A0D9SFB3_HUMAN,tr|A0A2R8YFS5|A0A2R8YFS5_HUMAN,tr|A0A0D9SF53|A0A0D9SF53_HUMAN,tr|C9J081|C9J081_HUMAN,tr|A0A2R8Y5G6|A0A2R8Y5G6_HUMAN,tr|A0A2R8Y7T2|A0A2R8Y7T2_HUMAN,tr|A0A0D9SG12|A0A0D9SG12_HUMAN,tr|H0Y960|H0Y960_HUMAN,tr|F6S8Q4|F6S8Q4_HUMAN,tr|A0A2U3TZJ9|A0A2U3TZJ9_HUMAN,tr|A0A2R8Y4A4|A0A2R8Y4A4_HUMAN" 21 1237.5431 1.6 63000 10691 2 1237.544086 619.7788 ATP-dependent RNA helicase DDX3X OS=Homo sapiens OX=9606 GN=DDX3X PE=1 SV=3 5.83 2191 - 3.92E+06 - - - 0.7903 - 2.131 0.544 - 255.4 1 2 0 0.001 12 0 0 0 5.22E+07 3.26E+07 - - - 5.0494 0.9997 221125_WJC_METTL3_EV_vs_WT_F05.10694.10694.2 0.000317 20-Sep R.SNPSIQATLNK[136.11].T sp|Q6UUV7|CRTC3_HUMAN 1 1179.6339 2.04 63003 10694 2 1179.635573 590.8242 CREB-regulated transcription coactivator 3 OS=Homo sapiens OX=9606 GN=CRTC3 PE=1 SV=2 8.47 2191.3 - 363071 - - - 1.4174 - 2.063 0.46 - 209.9 1 2 0 0.0017 11 0 0 0 1.36E+07 6.67E+06 - - - 4.3971 0.9994 221125_WJC_METTL3_EV_vs_WT_F05.10695.10695.2 0.000587 20-Sep R.HPTTGQILGYK[136.11].E "sp|Q15477|SKIV2_HUMAN,tr|B4E0B4|B4E0B4_HUMAN" 2 1221.6597 1.58 63004 10695 2 1221.661479 611.8371 Helicase SKI2W OS=Homo sapiens OX=9606 GN=SKIV2L PE=1 SV=3 8.6 2191.4 - 341163 - - - 1.4382 - 1.852 0.351 - 185.9 1 2 0 0.0018 11 0 0 0 7.82E+06 4.94E+06 - - - 3.3001 0.9999 221125_WJC_METTL3_EV_vs_WT_F05.10702.10702.3 0.000256 14/40 K.EVPAVPETLKK.K sp|P18124|RL7_HUMAN 1 1209.6969 1.11 63009 10702 3 1209.698045 404.2396 60S ribosomal protein L7 OS=Homo sapiens OX=9606 GN=RPL7 PE=1 SV=1 6.24 2192.4 - 4.43E+06 - - - 0.9556 - 2.118 0.428 - 207.6 1 2 0 0.0012 11 0 0 0 9.13E+07 8.23E+07 - - - 5.4434 0.9953 221125_WJC_METTL3_EV_vs_WT_F05.10704.10704.3 0.00863 Nov-40 R.ESVFTVEGGHR.A "sp|Q99623|PHB2_HUMAN,tr|F5H3X6|F5H3X6_HUMAN,tr|A0A7I2V5F0|A0A7I2V5F0_HUMAN,tr|F5GWA7|F5GWA7_HUMAN,tr|J3KPX7|J3KPX7_HUMAN,tr|F5GY37|F5GY37_HUMAN,tr|A0A3G2KQ93|A0A3G2KQ93_HUMAN,tr|F5H2D2|F5H2D2_HUMAN,tr|F5H0C5|F5H0C5_HUMAN" 9 1216.5837 1.02 63011 10704 3 1216.585036 406.5352 Prohibitin-2 OS=Homo sapiens OX=9606 GN=PHB2 PE=1 SV=2 5.4 2192.5 - 2.90E+06 - - - 1.1393 - 1.612 0.223 - 150.9 1 2 0 0.0014 11 0 0 0 9.59E+07 9.44E+07 - - - 2.3823 1 221125_WJC_METTL3_EV_vs_WT_F05.10705.10705.3 8.48E-05 15/44 K.SLEIQK[136.11]PAVAPR[166.11].H sp|P48634|PRC2A_HUMAN 1 1325.7786 1.18 63012 10705 3 1325.779359 442.9335 Protein PRRC2A OS=Homo sapiens OX=9606 GN=PRRC2A PE=1 SV=3 8.46 2192.6 - 1.21E+06 - - - 0.5687 - 2.285 0.523 - 254.7 1 2 0 0.0008 12 0 0 0 9.83E+07 8.35E+07 - - - 6.6613 0.9994 221125_WJC_METTL3_EV_vs_WT_F05.10708.10708.3 0.000596 13/40 R.NSLVDKPFAAK.E sp|Q14192|FHL2_HUMAN 1 1188.6503 1.07 63015 10708 3 1188.648526 397.224 Four and a half LIM domains protein 2 OS=Homo sapiens OX=9606 GN=FHL2 PE=1 SV=3 8.59 2192.9 - 600254 - - - -1.4697 - 2.308 0.266 - 221 1 2 0 -0.0017 11 0 0 0 1.11E+07 1.04E+07 - - - 3.8812 0.9996 221125_WJC_METTL3_EV_vs_WT_F05.10709.10709.2 0.0018 20-Sep R.HPTTGQILGYK.E "sp|Q15477|SKIV2_HUMAN,tr|B4E0B4|B4E0B4_HUMAN" 2 1213.6455 1.58 63016 10709 2 1213.645636 607.83 Helicase SKI2W OS=Homo sapiens OX=9606 GN=SKIV2L PE=1 SV=3 8.6 2193 - 585319 - - - 0.0939 - 1.654 0.377 - 221.3 1 2 0 0.0001 11 0 0 0 7.82E+06 4.94E+06 - - - 3.1868 0.9986 221125_WJC_METTL3_EV_vs_WT_F05.10710.10710.3 0.0343 Aug-40 R.YHGYQLVDGGR.F sp|Q86TJ2|TAD2B_HUMAN 1 1263.5996 1.37 63017 10710 3 1263.598392 422.2072 Transcriptional adapter 2-beta OS=Homo sapiens OX=9606 GN=TADA2B PE=1 SV=2 6.74 2193.1 - 490216 - - - -0.9837 - 1.715 0.269 - 114.2 1 2 0 -0.0012 11 0 0 0 8.98E+06 6.56E+06 - - - 3.0711 0.9991 221125_WJC_METTL3_EV_vs_WT_F05.10712.10712.2 0.000102 14-Oct R.DHINDIIK[136.11].L "sp|P46940|IQGA1_HUMAN,tr|H0YLE8|H0YLE8_HUMAN,tr|A0A0J9YXZ5|A0A0J9YXZ5_HUMAN" 3 974.5276 3.03 63019 10712 2 974.528479 488.2711 Ras GTPase-activating-like protein IQGAP1 OS=Homo sapiens OX=9606 GN=IQGAP1 PE=1 SV=1 5.21 2193.4 - 379003 - - - 0.8558 - 1.877 0.231 - 420.1 1 2 0 0.0008 8 0 0 0 6.44E+07 2.12E+07 - - - 2.646 0.9981 221125_WJC_METTL3_EV_vs_WT_F05.10714.10714.2 1.28E-08 15/24 K.LGHPDTLNQGEFK.E sp|P06702|S10A9_HUMAN 1 1454.7154 5026.04 63021 10714 2 1454.722737 728.365 Protein S100-A9 OS=Homo sapiens OX=9606 GN=S100A9 PE=1 SV=1 5.32 2193.6 - 310441 - - - 5.0484 - 2.975 0.482 - 413.2 1 2 0 0.0073 13 0 0 0 2.49E+08 4.95E+04 - - - 5.3969 0.9997 221125_WJC_METTL3_EV_vs_WT_F05.10720.10720.2 0.000263 22-Oct K.GIVEFSGKPAAR.K "sp|Q15233|NONO_HUMAN,tr|A0A7I2V535|A0A7I2V535_HUMAN,tr|A0A7I2V4N2|A0A7I2V4N2_HUMAN,tr|A0A7I2V464|A0A7I2V464_HUMAN,tr|A0A7P0MRW0|A0A7P0MRW0_HUMAN,tr|H7C367|H7C367_HUMAN,tr|C9IZL7|C9IZL7_HUMAN,tr|A0A7I2V4J2|A0A7I2V4J2_HUMAN,tr|A0A7I2V5Y7|A0A7I2V5Y7_HUMAN" 9 1230.6721 0.65 63025 10720 2 1230.673117 616.3433 Non-POU domain-containing octamer-binding protein OS=Homo sapiens OX=9606 GN=NONO PE=1 SV=4 8.75 2194.4 - 1.26E+06 - - - 0.8499 - 2.12 0.385 - 499.2 1 2 0 0.001 12 0 0 0 1.96E+07 2.99E+07 - - - 3.8614 0.9665 221125_WJC_METTL3_EV_vs_WT_F05.10721.10721.2 0.0136 16-Sep V.PAVPETLKK.K sp|P18124|RL7_HUMAN 1 981.5859 1.11 63026 10721 2 981.585827 491.8002 60S ribosomal protein L7 OS=Homo sapiens OX=9606 GN=RPL7 PE=1 SV=1 9.01 2194.5 - 1.14E+06 - - - -0.056 - 1.702 0.311 - 251.2 1 1 0 -0.0001 9 0 0 0 1.63E+07 1.46E+07 - - - 2.8766 0.9998 221125_WJC_METTL3_EV_vs_WT_F05.10723.10723.3 0.0217 13/48 K.VDNVEVLDHEEEK.N "sp|O00443|P3C2A_HUMAN,tr|A0A0C4DGF9|A0A0C4DGF9_HUMAN" 2 1553.7209 2.26 63028 10723 3 1553.721991 518.9143 Phosphatidylinositol 4-phosphate 3-kinase C2 domain-containing subunit alpha OS=Homo sapiens OX=9606 GN=PIK3C2A PE=1 SV=2 4.08 2194.7 - 734745 - - - 0.6816 - 1.768 0.394 - 145 1 2 0 0.0011 13 0 0 0 8.36E+06 3.70E+06 - - - 4.4774 0.9963 221125_WJC_METTL3_EV_vs_WT_F05.10724.10724.2 0.0294 20-Sep K.EVPAVPETLKK.K sp|P18124|RL7_HUMAN 1 1209.6969 1.13 63029 10724 2 1209.697676 605.8557 60S ribosomal protein L7 OS=Homo sapiens OX=9606 GN=RPL7 PE=1 SV=1 6.24 2194.9 - 682846 - - - 0.6506 - 1.514 0.17 - 217.5 1 2 0 0.0008 11 0 0 0 9.87E+06 8.70E+06 - - - 1.4184 0.9998 221125_WJC_METTL3_EV_vs_WT_F05.10725.10725.2 0.00026 20-Oct R.ESVFTVEGGHR.A "sp|Q99623|PHB2_HUMAN,tr|F5H3X6|F5H3X6_HUMAN,tr|A0A7I2V5F0|A0A7I2V5F0_HUMAN,tr|F5GWA7|F5GWA7_HUMAN,tr|J3KPX7|J3KPX7_HUMAN,tr|F5GY37|F5GY37_HUMAN,tr|A0A3G2KQ93|A0A3G2KQ93_HUMAN,tr|F5H2D2|F5H2D2_HUMAN,tr|F5H0C5|F5H0C5_HUMAN" 9 1216.5837 1.56 63030 10725 2 1216.584035 609.2991 Prohibitin-2 OS=Homo sapiens OX=9606 GN=PHB2 PE=1 SV=2 5.4 2195 - 613361 - - - 0.3165 - 1.953 0.422 - 406.5 1 2 0 0.0004 11 0 0 0 1.65E+07 1.06E+07 - - - 3.9686 0.9999 221125_WJC_METTL3_EV_vs_WT_F05.10728.10728.2 0.000766 24-Dec R.NSVTPLASPEPTK.K "sp|Q16875|F263_HUMAN,tr|A0A1W2PR17|A0A1W2PR17_HUMAN,tr|Q9H178|Q9H178_HUMAN,tr|Q5W015|Q5W015_HUMAN,tr|Q5VX20|Q5VX20_HUMAN" 5 1339.6983 3.76 63033 10728 2 1339.699322 670.8564 "6-phosphofructo-2-kinase\fructose-2,6-bisphosphatase 3 OS=Homo sapiens OX=9606 GN=PFKFB3 PE=1 SV=1" 6 2195.4 - 360227 - - - 0.7285 - 2.552 0.493 - 497 1 2 0 0.001 13 0 0 0 7.03E+07 1.87E+07 - - - 5.0865 0.9997 221125_WJC_METTL3_EV_vs_WT_F05.10733.10733.2 6.00E-05 26-Sep K.EVLC[160.03]PESQSPNGVR.F sp|Q14684|RRP1B_HUMAN 1 1570.741 0.78 63038 10733 2 1570.743445 786.3778 Ribosomal RNA processing protein 1 homolog B OS=Homo sapiens OX=9606 GN=RRP1B PE=1 SV=3 4.53 2196 - 118264 - - - 1.5846 - 1.88 0.495 - 198.7 1 2 0 0.0025 14 0 0 0 1.75E+06 2.24E+06 - - - 4.2804 0.9986 221125_WJC_METTL3_EV_vs_WT_F05.10734.10734.2 3.27E-06 26-Sep K.EVLC[160.03]PESQSPNGVR[166.11].F sp|Q14684|RRP1B_HUMAN 1 1580.7492 0.76 63039 10734 2 1580.742546 791.3819 Ribosomal RNA processing protein 1 homolog B OS=Homo sapiens OX=9606 GN=RRP1B PE=1 SV=3 4.53 2196.2 - 118117 - - - -4.2258 - 1.941 0.545 - 165.1 1 2 0 -0.0067 14 0 0 0 1.75E+06 2.30E+06 - - - 4.7285 0.9989 221125_WJC_METTL3_EV_vs_WT_F05.10737.10737.3 0.0271 Nov-40 R.ESVFTVEGGHR[166.11].A "sp|Q99623|PHB2_HUMAN,tr|F5H3X6|F5H3X6_HUMAN,tr|A0A7I2V5F0|A0A7I2V5F0_HUMAN,tr|F5GWA7|F5GWA7_HUMAN,tr|J3KPX7|J3KPX7_HUMAN,tr|F5GY37|F5GY37_HUMAN,tr|A0A3G2KQ93|A0A3G2KQ93_HUMAN,tr|F5H2D2|F5H2D2_HUMAN,tr|F5H0C5|F5H0C5_HUMAN" 9 1226.5919 1.02 63040 10737 3 1226.591053 409.8712 Prohibitin-2 OS=Homo sapiens OX=9606 GN=PHB2 PE=1 SV=2 5.4 2196.6 - 6.78E+06 - - - -0.7068 - 1.404 0.334 - 145.8 1 2 0 -0.0009 11 0 0 0 9.80E+07 9.63E+07 - - - 3.2275 0.9997 221125_WJC_METTL3_EV_vs_WT_F05.10738.10738.3 0.697 Nov-36 K.LFK[136.11]PPQPPAR[166.11].M "sp|O15372|EIF3H_HUMAN,tr|B3KS98|B3KS98_HUMAN,tr|A0A087WZK9|A0A087WZK9_HUMAN" 3 1167.6883 1.94 63041 10738 3 1167.687406 390.2367 Eukaryotic translation initiation factor 3 subunit H OS=Homo sapiens OX=9606 GN=EIF3H PE=1 SV=1 11 2196.6 - 5.84E+06 - - - -0.7947 - 2.087 0.325 - 140.9 1 2 0 -0.0009 10 0 0 0 2.18E+08 1.12E+08 - - - 4.3118 1 221125_WJC_METTL3_EV_vs_WT_F05.10741.10741.3 2.99E-05 15/40 R.TPSNELYK[136.11]PLR[166.11].A sp|Q8WUM4|PDC6I_HUMAN 1 1334.7313 1.02 63044 10741 3 1334.729946 445.9177 Programmed cell death 6-interacting protein OS=Homo sapiens OX=9606 GN=PDCD6IP PE=1 SV=1 8.26 2196.8 - 1.95E+06 - - - -1.0302 - 2.487 0.477 - 362.1 1 2 0 -0.0014 11 0 0 0 2.49E+07 2.45E+07 - - - 6.4459 0.9999 221125_WJC_METTL3_EV_vs_WT_F05.10742.10742.3 1.27E-05 14/40 R.TPSNELYKPLR.A sp|Q8WUM4|PDC6I_HUMAN 1 1316.7089 1.02 63045 10742 3 1316.706378 439.9102 Programmed cell death 6-interacting protein OS=Homo sapiens OX=9606 GN=PDCD6IP PE=1 SV=1 8.26 2196.9 - 1.50E+06 - - - -1.8782 - 2.235 0.453 - 217.8 1 2 0 -0.0025 11 0 0 0 2.49E+07 2.45E+07 - - - 5.8745 0.9991 221125_WJC_METTL3_EV_vs_WT_F05.10745.10745.2 0.00836 18-Sep K.KAIFTQETIK.E "sp|P82094|TMF1_HUMAN,tr|A0A2R8Y7M0|A0A2R8Y7M0_HUMAN" 2 1177.6707 1.49 63048 10745 2 1177.673736 589.8426 TATA element modulatory factor OS=Homo sapiens OX=9606 GN=TMF1 PE=1 SV=2 8.59 2197.3 - 196179 - - - 2.6 - 1.914 0.394 - 246.5 1 2 0 0.0031 10 0 0 0 1.45E+06 9.71E+05 - - - 3.7622 0.9998 221125_WJC_METTL3_EV_vs_WT_F05.10749.10749.2 3.04E-05 20-Oct R.ESVFTVEGGHR[166.11].A "sp|Q99623|PHB2_HUMAN,tr|F5H3X6|F5H3X6_HUMAN,tr|A0A7I2V5F0|A0A7I2V5F0_HUMAN,tr|F5GWA7|F5GWA7_HUMAN,tr|J3KPX7|J3KPX7_HUMAN,tr|F5GY37|F5GY37_HUMAN,tr|A0A3G2KQ93|A0A3G2KQ93_HUMAN,tr|F5H2D2|F5H2D2_HUMAN,tr|F5H0C5|F5H0C5_HUMAN" 9 1226.5919 1.61 63050 10749 2 1226.590216 614.3032 Prohibitin-2 OS=Homo sapiens OX=9606 GN=PHB2 PE=1 SV=2 5.4 2197.8 - 745377 - - - -1.3892 - 1.89 0.536 - 315.8 1 2 0 -0.0017 11 0 0 0 1.64E+07 1.02E+07 - - - 4.7215 0.9999 221125_WJC_METTL3_EV_vs_WT_F05.10750.10750.3 4.74E-07 15/44 R.GLQQITGHGGLR.G "sp|Q9UI09|NDUAC_HUMAN,tr|H0YID5|H0YID5_HUMAN,tr|F8VXI1|F8VXI1_HUMAN,tr|F8VRD8|F8VRD8_HUMAN,tr|A0A804HJF8|A0A804HJF8_HUMAN,tr|A0A804HK60|A0A804HK60_HUMAN,tr|A0A804HHX9|A0A804HHX9_HUMAN" 7 1235.6735 0.21 63051 10750 3 1235.668873 412.8984 NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 12 OS=Homo sapiens OX=9606 GN=NDUFA12 PE=1 SV=1 9.76 2197.9 - 737258 - - - -3.7186 - 3.181 0.494 - 270.4 1 2 0 -0.0046 12 0 0 0 8.17E+06 3.82E+07 - - - 7.2539 1 221125_WJC_METTL3_EV_vs_WT_F05.10752.10752.2 3.40E-05 13/24 K.GVEAVGSYAENQR.L "sp|Q12996|CSTF3_HUMAN,tr|E9PLP8|E9PLP8_HUMAN" 2 1378.6477 1.44 63053 10752 2 1378.647899 690.3311 Cleavage stimulation factor subunit 3 OS=Homo sapiens OX=9606 GN=CSTF3 PE=1 SV=1 4.53 2198.1 - 529379 - - - 0.1393 - 2.813 0.565 - 567.7 1 2 0 0.0002 13 0 0 0 1.98E+07 1.38E+07 - - - 5.8685 0.9998 221125_WJC_METTL3_EV_vs_WT_F05.10753.10753.2 0.000453 13/24 R.NSVTPLASPEPTK[136.11].K "sp|Q16875|F263_HUMAN,tr|A0A1W2PR17|A0A1W2PR17_HUMAN,tr|Q9H178|Q9H178_HUMAN,tr|Q5W015|Q5W015_HUMAN,tr|Q5VX20|Q5VX20_HUMAN" 5 1347.7125 3.75 63054 10753 2 1347.712111 674.8635 "6-phosphofructo-2-kinase\fructose-2,6-bisphosphatase 3 OS=Homo sapiens OX=9606 GN=PFKFB3 PE=1 SV=1" 6 2198.2 - 498084 - - - -0.3228 - 2.19 0.401 - 315.3 1 2 0 -0.0004 13 0 0 0 7.02E+07 1.87E+07 - - - 4.0146 0.9998 221125_WJC_METTL3_EV_vs_WT_F05.10754.10754.3 0.0043 Dec-36 R.KIALEDVPEK.Q sp|O43148|MCES_HUMAN 1 1140.639 0.75 63055 10754 3 1140.636705 381.2203 mRNA cap guanine-N7 methyltransferase OS=Homo sapiens OX=9606 GN=RNMT PE=1 SV=1 4.68 2198.4 - 431807 - - - -2.0471 - 2.149 0.389 - 208.9 1 2 0 -0.0023 10 0 0 0 9.81E+06 1.30E+07 - - - 5.1105 0.9944 221125_WJC_METTL3_EV_vs_WT_F05.10760.10760.2 9.53E-08 13/24 F.ILDQTNVSAAAQR.R "sp|Q00839|HNRPU_HUMAN,tr|A0A1W2PQL0|A0A1W2PQL0_HUMAN,tr|A0A1W2PPL4|A0A1W2PPL4_HUMAN,tr|A0A1W2PQ74|A0A1W2PQ74_HUMAN,tr|Q5RI18|Q5RI18_HUMAN,tr|A0A1W2PP35|A0A1W2PP35_HUMAN,tr|A0A1W2PPS1|A0A1W2PPS1_HUMAN,tr|A0A1W2PRZ7|A0A1W2PRZ7_HUMAN,tr|A0A1W2PPH7|A0A1W2PPH7_HUMAN,tr|A0A1W2PQD4|A0A1W2PQD4_HUMAN,tr|A0A1W2PP34|A0A1W2PP34_HUMAN,tr|A0A1X7SBS1|A0A1X7SBS1_HUMAN" 12 1385.7263 1.03 63059 10760 2 1385.727164 693.8704 Heterogeneous nuclear ribonucleoprotein U OS=Homo sapiens OX=9606 GN=HNRNPU PE=1 SV=6 5.84 2199 - 1.80E+06 - - - 0.6293 - 2.755 0.551 - 626.6 1 1 0 0.0009 13 0 0 0 3.44E+07 3.33E+07 - - - 5.7114 0.9569 221125_WJC_METTL3_EV_vs_WT_F05.10763.10763.3 0.0216 Nov-48 K.VVDR[166.11]DSEEAEIIR[166.11].K "sp|P09874|PARP1_HUMAN,tr|A0A7I2V3E1|A0A7I2V3E1_HUMAN" 2 1549.7851 1.02 63062 10763 3 1549.775477 517.6023 Poly [ADP-ribose] polymerase 1 OS=Homo sapiens OX=9606 GN=PARP1 PE=1 SV=4 4.18 2199.4 - 663430 - - - -6.2028 - 2.214 0.327 - 176 1 2 1 -0.0096 13 0 0 0 1.13E+08 1.11E+08 - - - 4.338 0.9909 221125_WJC_METTL3_EV_vs_WT_F05.10766.10766.2 2.05E-05 18-Nov K.ESSSESFISR.L "sp|Q9P2R3|ANFY1_HUMAN,tr|I3L3P8|I3L3P8_HUMAN" 2 1127.5095 1.49 63065 10766 2 1127.514564 564.762 Rabankyrin-5 OS=Homo sapiens OX=9606 GN=ANKFY1 PE=1 SV=2 4.53 2199.7 - 357850 - - - 4.5073 - 2.112 0.22 - 525.9 1 2 0 0.0051 10 0 0 0 8.51E+06 5.72E+06 - - - 2.7512 0.998 221125_WJC_METTL3_EV_vs_WT_F05.10767.10767.2 1.35E-06 18-Nov K.ESSSESFISR[166.11].L "sp|Q9P2R3|ANFY1_HUMAN,tr|I3L3P8|I3L3P8_HUMAN" 2 1137.5178 1.49 63066 10767 2 1137.514426 569.7662 Rabankyrin-5 OS=Homo sapiens OX=9606 GN=ANKFY1 PE=1 SV=2 4.53 2199.9 - 288363 - - - -2.9239 - 2.227 0.243 - 654.1 1 2 0 -0.0033 10 0 0 0 8.51E+06 5.72E+06 - - - 3.0696 0.9995 221125_WJC_METTL3_EV_vs_WT_F05.10770.10770.3 0.00141 Sep-40 K.ELDTDRPSLVR.R "sp|Q9NRA8|4ET_HUMAN,tr|B1AKL5|B1AKL5_HUMAN,tr|B1AKL4|B1AKL4_HUMAN" 3 1299.6783 1.26 63067 10770 3 1299.678646 434.2334 Eukaryotic translation initiation factor 4E transporter OS=Homo sapiens OX=9606 GN=EIF4ENIF1 PE=1 SV=2 4.56 2200.3 - 457953 - - - 0.2824 - 1.774 0.33 - 158 1 2 0 0.0004 11 0 0 0 2.98E+07 2.36E+07 - - - 3.8475 0.9895 221125_WJC_METTL3_EV_vs_WT_F05.10771.10771.3 0.0192 13/40 K.LRQQDLDGELR.S sp|Q99459|CDC5L_HUMAN 1 1341.7001 1.4 63068 10771 3 1341.694768 448.2406 Cell division cycle 5-like protein OS=Homo sapiens OX=9606 GN=CDC5L PE=1 SV=2 4.56 2200.4 - 684002 - - - -3.9569 - 2.309 0.296 - 327.4 1 2 1 -0.0053 11 0 0 0 1.22E+07 8.66E+06 - - - 4.2159 0.9993 221125_WJC_METTL3_EV_vs_WT_F05.10773.10773.3 0.0617 Sep-40 R.DGYIHYGQTVK.L "sp|Q06330|SUH_HUMAN,tr|A0A7P0Z4N7|A0A7P0Z4N7_HUMAN,tr|D6RF98|D6RF98_HUMAN,tr|D6R927|D6R927_HUMAN,tr|A0A7P0T9Y9|A0A7P0T9Y9_HUMAN,tr|A0A7P0T947|A0A7P0T947_HUMAN,tr|A0A7P0TBJ4|A0A7P0TBJ4_HUMAN" 7 1279.6197 0.08 63070 10773 3 1279.620584 427.5472 Recombining binding protein suppressor of hairless OS=Homo sapiens OX=9606 GN=RBPJ PE=1 SV=3 6.74 2200.6 - 365667 - - - 0.69 - 1.779 0.301 - 94.4 1 2 0 0.0009 11 0 0 0 4.88E+06 6.22E+07 - - - 3.5321 0.9983 221125_WJC_METTL3_EV_vs_WT_F05.10777.10777.2 0.107 16-Nov R.C[160.03]RPFNLAER.K "sp|P52732|KIF11_HUMAN,tr|A0A7I2YQY4|A0A7I2YQY4_HUMAN,tr|A0A7I2V3V3|A0A7I2V3V3_HUMAN" 3 1161.5713 3.39 63072 10777 2 1161.568721 581.7929 Kinesin-like protein KIF11 OS=Homo sapiens OX=9606 GN=KIF11 PE=1 SV=2 8.25 2201.2 - 462358 - - - -2.2306 - 1.945 0.243 - 307.2 1 2 0 -0.0026 9 0 0 0 2.89E+07 8.52E+06 - - - 2.7596 1 221125_WJC_METTL3_EV_vs_WT_F05.10778.10778.3 3.38E-07 19/48 K.VVDRDSEEAEIIR.K "sp|P09874|PARP1_HUMAN,tr|A0A7I2V3E1|A0A7I2V3E1_HUMAN" 2 1529.7686 1.02 63073 10778 3 1529.765839 510.9301 Poly [ADP-ribose] polymerase 1 OS=Homo sapiens OX=9606 GN=PARP1 PE=1 SV=4 4.18 2201.3 - 1.56E+06 - - - -1.7722 - 3.301 0.639 - 719.5 1 2 1 -0.0027 13 0 0 0 1.13E+08 1.10E+08 - - - 8.9014 0.9999 221125_WJC_METTL3_EV_vs_WT_F05.10782.10782.2 1.34E-05 14/18 K.HTVDDGLDIR[166.11].K "sp|Q86VP6|CAND1_HUMAN,tr|A0A0C4DGH5|A0A0C4DGH5_HUMAN" 2 1149.5654 0.46 63075 10782 2 1149.56516 575.79 Cullin-associated NEDD8-dissociated protein 1 OS=Homo sapiens OX=9606 GN=CAND1 PE=1 SV=2 4.41 2201.8 - 608835 - - - -0.1835 - 1.836 0.528 - 561.4 1 2 0 -0.0002 10 0 0 0 4.59E+06 9.88E+06 - - - 4.6367 0.9963 221125_WJC_METTL3_EV_vs_WT_F05.10783.10783.3 0.00188 Aug-48 K.GVEAVGSYAENQR.L "sp|Q12996|CSTF3_HUMAN,tr|E9PLP8|E9PLP8_HUMAN" 2 1378.6477 1.79 63076 10783 3 1378.641379 460.5565 Cleavage stimulation factor subunit 3 OS=Homo sapiens OX=9606 GN=CSTF3 PE=1 SV=1 4.53 2201.9 - 444233 - - - -4.59 - 1.674 0.382 - 66.2 1 2 0 -0.0063 13 0 0 0 5.59E+06 3.12E+06 - - - 4.1941 0.9988 221125_WJC_METTL3_EV_vs_WT_F05.10785.10785.2 0.00674 20-Oct K.IDEPLEGSEDR[166.11].L "sp|P61978|HNRPK_HUMAN,tr|S4R359|S4R359_HUMAN" 2 1268.576 1.59 63078 10785 2 1268.570964 635.2953 Heterogeneous nuclear ribonucleoprotein K OS=Homo sapiens OX=9606 GN=HNRNPK PE=1 SV=1 3.83 2202.2 - 618088 - - - -3.9659 - 2.177 0.484 - 453.4 1 2 0 -0.005 11 0 0 0 2.49E+07 1.57E+07 - - - 4.7188 0.9997 221125_WJC_METTL3_EV_vs_WT_F05.10786.10786.3 0.000117 Dec-48 R.LVEIVHPSQEEDR[166.11].H "sp|Q5H9R7|PP6R3_HUMAN,tr|H7BXH2|H7BXH2_HUMAN,tr|E9PK08|E9PK08_HUMAN,tr|E9PKF6|E9PKF6_HUMAN" 4 1559.7819 5.74 63079 10786 3 1559.786096 520.9346 Serine\threonine-protein phosphatase 6 regulatory subunit 3 OS=Homo sapiens OX=9606 GN=PPP6R3 PE=1 SV=2 4.4 2202.3 - 482533 - - - 2.6863 - 1.987 0.42 - 145.4 1 2 0 0.0042 13 0 0 0 5.51E+07 9.60E+06 - - - 5.0831 0.9981 221125_WJC_METTL3_EV_vs_WT_F05.10788.10788.2 6.01E-05 18-Aug K.NLDDGIDDER[166.11].L "sp|Q9H361|PABP3_HUMAN,sp|P11940|PABP1_HUMAN,tr|A0A7I2YQE4|A0A7I2YQE4_HUMAN,tr|A0A7I2V649|A0A7I2V649_HUMAN,tr|H0YAR2|H0YAR2_HUMAN,tr|E7ERJ7|E7ERJ7_HUMAN,tr|A0A7I2YQ88|A0A7I2YQ88_HUMAN,tr|A0A087WTT1|A0A087WTT1_HUMAN,tr|H0YAP2|H0YAP2_HUMAN,tr|A0A7I2V4N4|A0A7I2V4N4_HUMAN,tr|E7EQV3|E7EQV3_HUMAN" 11 1170.5028 1.4 63081 10788 2 1170.497897 586.2587 Polyadenylate-binding protein 3 OS=Homo sapiens OX=9606 GN=PABPC3 PE=1 SV=2 3.71 2202.6 - 395298 - - - -4.2144 - 1.653 0.514 - 211.3 1 2 0 -0.0049 10 0 0 0 7.15E+06 5.10E+06 - - - 4.2387 0.9891 221125_WJC_METTL3_EV_vs_WT_F05.10789.10789.2 0.0985 16-Jun R.C[160.03]R[166.11]PFNLAER[166.11].K "sp|P52732|KIF11_HUMAN,tr|A0A7I2YQY4|A0A7I2YQY4_HUMAN,tr|A0A7I2V3V3|A0A7I2V3V3_HUMAN" 3 1181.5879 3.39 63082 10789 2 1181.586946 591.8012 Kinesin-like protein KIF11 OS=Homo sapiens OX=9606 GN=KIF11 PE=1 SV=2 8.25 2202.7 - 233244 - - - -0.7668 - 1.269 0.139 - 71.8 2 2 0 -0.0009 9 0 0 0 2.89E+07 8.52E+06 - - - 0.6221 1 221125_WJC_METTL3_EV_vs_WT_F05.10792.10792.3 6.02E-05 Nov-32 R.C[160.03]RPFNLAER.K "sp|P52732|KIF11_HUMAN,tr|A0A7I2YQY4|A0A7I2YQY4_HUMAN,tr|A0A7I2V3V3|A0A7I2V3V3_HUMAN" 3 1161.5713 4.7 63083 10792 3 1161.570004 388.1977 Kinesin-like protein KIF11 OS=Homo sapiens OX=9606 GN=KIF11 PE=1 SV=2 8.25 2203.1 - 6.23E+06 - - - -1.1261 - 2.351 0.438 - 283 1 2 0 -0.0013 9 0 0 0 1.56E+08 3.32E+07 - - - 5.9992 1 221125_WJC_METTL3_EV_vs_WT_F05.10796.10796.2 9.91E-07 13/28 K.DVASTAGEEGDTSLR.E "sp|Q8ND24|RN214_HUMAN,tr|E9PRE9|E9PRE9_HUMAN" 2 1506.6798 3.32 63087 10796 2 1506.678657 754.3472 RING finger protein 214 OS=Homo sapiens OX=9606 GN=RNF214 PE=1 SV=2 3.92 2203.5 - 465265 - - - -0.7553 - 2.652 0.652 - 527.1 1 2 0 -0.0011 15 0 0 0 5.23E+06 1.58E+06 - - - 6.2542 0.9953 221125_WJC_METTL3_EV_vs_WT_F05.10799.10799.2 0.0261 13/24 K.VVDR[166.11]DSEEAEIIR[166.11].K "sp|P09874|PARP1_HUMAN,tr|A0A7I2V3E1|A0A7I2V3E1_HUMAN" 2 1549.7851 0.95 63090 10799 2 1549.78111 775.8998 Poly [ADP-ribose] polymerase 1 OS=Homo sapiens OX=9606 GN=PARP1 PE=1 SV=4 4.18 2203.9 - 319346 - - - -2.5681 - 2.499 0.453 - 172.3 1 2 1 -0.004 13 0 0 0 6.70E+06 7.08E+06 - - - 4.7363 0.9986 221125_WJC_METTL3_EV_vs_WT_F05.10801.10801.2 0.000143 15/24 K.VVDRDSEEAEIIR.K "sp|P09874|PARP1_HUMAN,tr|A0A7I2V3E1|A0A7I2V3E1_HUMAN" 2 1529.7686 0.95 63092 10801 2 1529.770132 765.8916 Poly [ADP-ribose] polymerase 1 OS=Homo sapiens OX=9606 GN=PARP1 PE=1 SV=4 4.18 2204.1 - 268727 - - - 1.0341 - 2.688 0.513 - 267.7 1 2 1 0.0016 13 0 0 0 6.70E+06 7.08E+06 - - - 5.3673 1 221125_WJC_METTL3_EV_vs_WT_F05.10802.10802.2 1.54E-09 28-Dec R.SLAEAC[160.03]SDGDVNAVR.K "sp|Q8IWZ3|ANKH1_HUMAN,tr|E9PDP5|E9PDP5_HUMAN,tr|D6RHC4|D6RHC4_HUMAN" 3 1562.6995 1.48 63093 10802 2 1562.699591 782.357 Ankyrin repeat and KH domain-containing protein 1 OS=Homo sapiens OX=9606 GN=ANKHD1 PE=1 SV=1 4.03 2204.3 - 248094 - - - 0.0678 - 2.848 0.703 - 458.4 1 2 0 0.0001 15 0 0 0 2.66E+07 1.79E+07 - - - 6.8065 1 221125_WJC_METTL3_EV_vs_WT_F05.10803.10803.2 5.59E-09 15/28 R.SLAEAC[160.03]SDGDVNAVR[166.11].K "sp|Q8IWZ3|ANKH1_HUMAN,tr|E9PDP5|E9PDP5_HUMAN,tr|D6RHC4|D6RHC4_HUMAN" 3 1572.7078 1.48 63094 10803 2 1572.706698 787.3612 Ankyrin repeat and KH domain-containing protein 1 OS=Homo sapiens OX=9606 GN=ANKHD1 PE=1 SV=1 4.03 2204.4 - 216202 - - - -0.6721 - 3.305 0.655 - 781.8 1 2 0 -0.0011 15 0 0 0 2.66E+07 1.79E+07 - - - 6.8175 0.9203 221125_WJC_METTL3_EV_vs_WT_F05.10805.10805.2 0.000476 28-Jun K.DVASTAGEEGDTSLR[166.11].E "sp|Q8ND24|RN214_HUMAN,tr|E9PRE9|E9PRE9_HUMAN" 2 1516.6881 3.32 63096 10805 2 1517.687606 759.3513 RING finger protein 214 OS=Homo sapiens OX=9606 GN=RNF214 PE=1 SV=2 3.92 2204.7 - 133872 - - - 659.0287 - 1.426 0.424 - 86.2 1 2 0 0.9995 15 0 0 0 5.23E+06 1.58E+06 - - - 2.7313 0.9997 221125_WJC_METTL3_EV_vs_WT_F05.10807.10807.2 5.76E-05 22-Oct R.QQPDTEAVLNGK[136.11].G "sp|P54105|ICLN_HUMAN,tr|E9PJF4|E9PJF4_HUMAN,tr|J3KN38|J3KN38_HUMAN,tr|E9PMI6|E9PMI6_HUMAN,tr|E9PQ83|E9PQ83_HUMAN" 5 1306.6608 2.59 63097 10807 2 1306.658194 654.3377 Methylosome subunit pICln OS=Homo sapiens OX=9606 GN=CLNS1A PE=1 SV=1 4.37 2204.9 - 412297 - - - -2.0281 - 2.243 0.467 - 418.8 1 2 0 -0.0027 12 0 0 0 3.77E+07 1.46E+07 - - - 4.6149 0.9999 221125_WJC_METTL3_EV_vs_WT_F05.10809.10809.3 0.000135 Dec-36 K.SLGHFENLQK.Y "sp|Q9ULV3|CIZ1_HUMAN,tr|Q5SYW2|Q5SYW2_HUMAN,tr|F5H2X7|F5H2X7_HUMAN,tr|H0Y5D5|H0Y5D5_HUMAN,tr|A0A0U1RQR2|A0A0U1RQR2_HUMAN,tr|A0A494C0L7|A0A494C0L7_HUMAN,tr|Q9BTG3|Q9BTG3_HUMAN" 7 1171.5986 2.23 63098 10809 3 1171.598255 391.5401 Cip1-interacting zinc finger protein OS=Homo sapiens OX=9606 GN=CIZ1 PE=1 SV=2 6.47 2205.1 - 3.70E+06 - - - -0.2706 - 1.981 0.451 - 150.3 1 2 0 -0.0003 10 0 0 0 1.08E+08 4.82E+07 - - - 5.5645 0.9999 221125_WJC_METTL3_EV_vs_WT_F05.10810.10810.2 3.66E-06 18-Nov R.SGVSLAALK[136.11]K[136.11].A "sp|P10412|H14_HUMAN,sp|P16403|H12_HUMAN,sp|P16402|H13_HUMAN" 3 988.6252 0.67 63099 10810 2 988.624953 495.3199 Histone H1.4 OS=Homo sapiens OX=9606 GN=H1-4 PE=1 SV=2 10 2205.2 - 1.97E+06 - - - -0.2306 - 2.345 0.481 - 321.4 1 2 0 -0.0002 10 0 0 0 2.52E+07 3.75E+07 - - - 4.9726 0.9753 221125_WJC_METTL3_EV_vs_WT_F05.10812.10812.2 0.0187 16-Sep S.GVSLAALK[136.11]K[136.11].A "sp|P10412|H14_HUMAN,sp|Q02539|H11_HUMAN,sp|P16403|H12_HUMAN,sp|P16402|H13_HUMAN" 4 901.5932 1.12 63101 10812 2 901.593102 451.8039 Histone H1.4 OS=Homo sapiens OX=9606 GN=H1-4 PE=1 SV=2 10 2205.4 - 622010 - - - -0.0566 - 2.028 0.285 - 243.9 1 1 0 -0.0001 9 0 0 0 1.10E+07 9.84E+06 - - - 3.1915 0.9998 221125_WJC_METTL3_EV_vs_WT_F05.10813.10813.2 3.70E-06 18-Dec R.SGFSSVSVSR.S sp|P02538|K2C6A_HUMAN 1 1011.4985 999 63102 10813 2 1011.499291 506.7565 "Keratin, type II cytoskeletal 6A OS=Homo sapiens OX=9606 GN=KRT6A PE=1 SV=3" 9.47 2205.6 - 488999 - - - 0.7593 - 2.357 0.385 - 374.1 1 2 0 0.0008 10 0 0 0 9.89E+07 0.00E+00 - - - 4.2776 0.9997 221125_WJC_METTL3_EV_vs_WT_F05.10814.10814.2 1.51E-05 22-Oct K.VGSVEEFQGQER[166.11].S "sp|Q9HCE1|MOV10_HUMAN,tr|Q5JR04|Q5JR04_HUMAN" 2 1373.6451 1.26 63103 10814 2 1373.64776 687.8298 Helicase MOV-10 OS=Homo sapiens OX=9606 GN=MOV10 PE=1 SV=2 4.25 2205.7 - 422548 - - - 1.9525 - 2.378 0.489 - 390.6 1 2 0 0.0027 12 0 0 0 3.79E+06 3.01E+06 - - - 4.9312 0.9999 221125_WJC_METTL3_EV_vs_WT_F05.10815.10815.2 9.59E-07 22-Oct K.VGSVEEFQGQER.S "sp|Q9HCE1|MOV10_HUMAN,tr|Q5JR04|Q5JR04_HUMAN" 2 1363.6368 1.21 63104 10815 2 1363.636037 682.8257 Helicase MOV-10 OS=Homo sapiens OX=9606 GN=MOV10 PE=1 SV=2 4.25 2205.8 - 397328 - - - -0.5654 - 2.287 0.57 - 431.6 1 2 0 -0.0008 12 0 0 0 3.79E+06 3.13E+06 - - - 5.4274 1 221125_WJC_METTL3_EV_vs_WT_F05.10817.10817.2 5.81E-10 14/30 R.AAAYSAQVQPVDGATR[166.11].K "sp|Q9H7E9|CH033_HUMAN,tr|A0A3B3IRR6|A0A3B3IRR6_HUMAN,tr|A0A3B3ITA3|A0A3B3ITA3_HUMAN,tr|A0A3B3IT54|A0A3B3IT54_HUMAN" 4 1613.8037 1.18 63106 10817 2 1613.801432 807.9091 UPF0488 protein C8orf33 OS=Homo sapiens OX=9606 GN=C8orf33 PE=1 SV=1 5.88 2206.1 - 359923 - - - -1.4079 - 3.036 0.683 - 522.5 1 2 0 -0.0023 16 0 0 0 6.58E+06 5.56E+06 - - - 6.8152 0.9997 221125_WJC_METTL3_EV_vs_WT_F05.10818.10818.2 0.00142 26-Sep K.ILSEVTPDQSKPEN.- sp|O43482|MS18B_HUMAN 1 1555.773 1.09 63107 10818 2 1555.770436 778.8938 Protein Mis18-beta OS=Homo sapiens OX=9606 GN=OIP5 PE=1 SV=2 4.14 2206.2 - 352395 - - - -1.6268 - 1.898 0.499 - 172.8 1 2 0 -0.0025 14 0 0 0 5.46E+06 4.99E+06 - - - 4.3339 1 221125_WJC_METTL3_EV_vs_WT_F05.10819.10819.2 5.49E-08 17/30 R.AAAYSAQVQPVDGATR.K "sp|Q9H7E9|CH033_HUMAN,tr|A0A3B3IRR6|A0A3B3IRR6_HUMAN,tr|A0A3B3ITA3|A0A3B3ITA3_HUMAN,tr|A0A3B3IT54|A0A3B3IT54_HUMAN" 4 1603.7954 1.18 63108 10819 2 1603.796616 802.905 UPF0488 protein C8orf33 OS=Homo sapiens OX=9606 GN=C8orf33 PE=1 SV=1 5.88 2206.3 - 320414 - - - 0.737 - 3.513 0.677 - 876.6 1 2 0 0.0012 16 0 0 0 6.58E+06 5.56E+06 - - - 7.13 1 221125_WJC_METTL3_EV_vs_WT_F05.10823.10823.2 3.74E-11 15/28 R.C[160.03]TGGEVGATSALAPK.L sp|P30050|RL12_HUMAN 1 1417.6871 1.4 63112 10823 2 1417.690241 709.8508 60S ribosomal protein L12 OS=Homo sapiens OX=9606 GN=RPL12 PE=1 SV=1 5.99 2206.9 - 159976 - - - 2.1951 - 3.079 0.661 - 834 1 2 0 0.0031 15 0 0 0 2.05E+08 1.46E+08 - - - 6.6871 0.9996 221125_WJC_METTL3_EV_vs_WT_F05.10825.10825.3 0.00014 Dec-36 K.LFKPPQPPAR.M "sp|O15372|EIF3H_HUMAN,tr|B3KS98|B3KS98_HUMAN,tr|A0A087WZK9|A0A087WZK9_HUMAN" 3 1149.6659 1.94 63113 10825 3 1149.666011 384.2292 Eukaryotic translation initiation factor 3 subunit H OS=Homo sapiens OX=9606 GN=EIF3H PE=1 SV=1 11 2207.1 - 7.04E+06 - - - 0.1279 - 2.283 0.282 - 216.1 1 2 0 0.0001 10 0 0 0 2.18E+08 1.12E+08 - - - 4.0948 0.9999 221125_WJC_METTL3_EV_vs_WT_F05.10826.10826.2 5.31E-05 22-Dec R.QQPDTEAVLNGK.G "sp|P54105|ICLN_HUMAN,tr|E9PJF4|E9PJF4_HUMAN,tr|J3KN38|J3KN38_HUMAN,tr|E9PMI6|E9PMI6_HUMAN,tr|E9PQ83|E9PQ83_HUMAN" 5 1298.6466 2.5 63114 10826 2 1298.645051 650.3306 Methylosome subunit pICln OS=Homo sapiens OX=9606 GN=CLNS1A PE=1 SV=1 4.37 2207.2 - 1.15E+06 - - - -1.2267 - 2.391 0.589 - 704.7 1 2 0 -0.0016 12 0 0 0 3.32E+07 1.33E+07 - - - 5.6845 0.9998 221125_WJC_METTL3_EV_vs_WT_F05.10829.10829.3 1.47E-05 15/52 K.LLDGPSTEK[136.11]DLDEK[136.11].K "sp|P23193|TCEA1_HUMAN,tr|A0A1W2PRL9|A0A1W2PRL9_HUMAN,tr|A0A1W2PPZ5|A0A1W2PPZ5_HUMAN,tr|E5RIS7|E5RIS7_HUMAN" 4 1574.801 1.05 63117 10829 3 1574.801416 525.941 Transcription elongation factor A protein 1 OS=Homo sapiens OX=9606 GN=TCEA1 PE=1 SV=2 4.11 2207.6 - 616779 - - - 0.2432 - 2.704 0.431 - 301.9 1 2 1 0.0004 14 0 0 0 1.84E+07 1.75E+07 - - - 5.9887 0.9955 221125_WJC_METTL3_EV_vs_WT_F05.10830.10830.2 0.0387 16-Jul R.SREDMIDIK.L "sp|P20340|RAB6A_HUMAN,tr|F5H3K7|F5H3K7_HUMAN" 2 1105.5438 0.92 63118 10830 2 1105.544281 553.7792 Ras-related protein Rab-6A OS=Homo sapiens OX=9606 GN=RAB6A PE=1 SV=3 4.56 2207.8 - 616510 - - - 0.4722 - 1.903 0.329 - 169.5 1 2 1 0.0005 9 0 0 0 7.12E+06 7.78E+06 - - - 3.3323 0.9998 221125_WJC_METTL3_EV_vs_WT_F05.10833.10833.2 0.000267 20-Dec R.TQSSSNLAELR.Q "sp|P27986|P85A_HUMAN,tr|H0YB27|H0YB27_HUMAN" 2 1204.6048 1.46 63121 10833 2 1204.602714 603.3097 Phosphatidylinositol 3-kinase regulatory subunit alpha OS=Homo sapiens OX=9606 GN=PIK3R1 PE=1 SV=2 5.66 2208.1 - 351623 - - - -1.7151 - 2.305 0.505 - 568.5 1 2 0 -0.0021 11 0 0 0 2.56E+06 1.75E+06 - - - 5.0294 0.9981 221125_WJC_METTL3_EV_vs_WT_F05.10834.10834.3 0.00158 Nov-48 K.VVDRDSEEAEIIR[166.11].K "sp|P09874|PARP1_HUMAN,tr|A0A7I2V3E1|A0A7I2V3E1_HUMAN" 2 1539.7768 - 63122 10834 3 1539.781096 514.2662 Poly [ADP-ribose] polymerase 1 OS=Homo sapiens OX=9606 GN=PARP1 PE=1 SV=4 4.18 2208.3 - 278047 - - - 2.777 - 2.024 0.405 - 194.8 1 2 1 0.0043 13 0 0 0 - - - - - 4.9658 0.9997 221125_WJC_METTL3_EV_vs_WT_F05.10840.10840.2 0.000769 18-Oct R.SGVSLAALKK.A "sp|P10412|H14_HUMAN,sp|P16403|H12_HUMAN,sp|P16402|H13_HUMAN" 3 972.5968 0.67 63126 10840 2 972.597918 487.3057 Histone H1.4 OS=Homo sapiens OX=9606 GN=H1-4 PE=1 SV=2 10 2209 - 2.84E+06 - - - 1.169 - 1.95 0.403 - 316.8 1 2 0 0.0011 10 0 0 0 2.52E+07 3.75E+07 - - - 3.8813 0.9999 221125_WJC_METTL3_EV_vs_WT_F05.10842.10842.3 0.000469 Dec-40 K.GAIDHYVTPVK[136.11].A "sp|Q9NX20|RM16_HUMAN,tr|E9PI14|E9PI14_HUMAN" 2 1206.6488 1.02 63128 10842 3 1206.64964 403.2236 "39S ribosomal protein L16, mitochondrial OS=Homo sapiens OX=9606 GN=MRPL16 PE=1 SV=1" 6.74 2209.1 - 1.17E+06 - - - 0.6771 - 2.064 0.457 - 164.2 1 2 0 0.0008 11 0 0 0 1.38E+07 1.35E+07 - - - 5.6935 0.9564 221125_WJC_METTL3_EV_vs_WT_F05.10843.10843.2 0.0158 14-Jul G.VSLAALK[136.11]K[136.11].A "sp|P10412|H14_HUMAN,sp|Q02539|H11_HUMAN,sp|P16403|H12_HUMAN,sp|P16402|H13_HUMAN" 4 844.5717 1.13 63129 10843 2 844.571674 423.2931 Histone H1.4 OS=Homo sapiens OX=9606 GN=H1-4 PE=1 SV=2 10 2209.2 - 877152 - - - -0.0178 - 1.574 0.299 - 111.8 1 1 0 0 8 0 0 0 7.44E+06 6.57E+06 - - - 2.6175 0.9939 221125_WJC_METTL3_EV_vs_WT_F05.10844.10844.2 2.94E-06 14/22 F.SSGGFSGGSFSR.G "sp|P13645|K1C10_HUMAN,tr|A0A1B0GVI3|A0A1B0GVI3_HUMAN" 2 1131.4945 16.29 63130 10844 2 1131.495355 566.7545 "Keratin, type I cytoskeletal 10 OS=Homo sapiens OX=9606 GN=KRT10 PE=1 SV=6" 9.47 2209.3 - 625195 - - - 0.7548 - 2.458 0.567 - 723 1 1 0 0.0009 12 0 0 0 2.79E+07 1.71E+06 - - - 5.5949 0.9998 221125_WJC_METTL3_EV_vs_WT_F05.10846.10846.2 3.37E-05 20-Oct K.HGYAPSDLPVK[136.11].A "sp|Q9Y5Q8|TF3C5_HUMAN,tr|Q5T7U1|Q5T7U1_HUMAN,tr|Q5T7U0|Q5T7U0_HUMAN,tr|H7BY84|H7BY84_HUMAN,tr|H0Y5D2|H0Y5D2_HUMAN" 5 1190.6175 1.12 63132 10846 2 1190.619143 596.316 General transcription factor 3C polypeptide 5 OS=Homo sapiens OX=9606 GN=GTF3C5 PE=1 SV=2 6.74 2209.6 - 416332 - - - 1.3606 - 2.176 0.511 - 354.4 1 2 0 0.0016 11 0 0 0 4.25E+06 3.80E+06 - - - 4.918 0.9986 221125_WJC_METTL3_EV_vs_WT_F05.10847.10847.3 0.0366 Jul-48 K.LIQDQQEQIQHLK.S "sp|Q92878|RAD50_HUMAN,tr|A0A494C1B7|A0A494C1B7_HUMAN,tr|A0A1W2PQ90|A0A1W2PQ90_HUMAN" 3 1619.8631 1.24 63133 10847 3 1619.864062 540.9616 DNA repair protein RAD50 OS=Homo sapiens OX=9606 GN=RAD50 PE=1 SV=1 5.32 2209.7 - 396166 - - - 0.5815 - 1.655 0.282 - 54.1 1 2 0 0.0009 13 0 0 0 4.89E+06 3.95E+06 - - - 3.0497 0.9999 221125_WJC_METTL3_EV_vs_WT_F05.10849.10849.2 6.37E-06 28-Nov R.GPQLVC[160.03]TGSDDGTVK[136.11].L sp|Q96DI7|SNR40_HUMAN 1 1540.7283 2.23 63135 10849 2 1540.727646 771.3714 U5 small nuclear ribonucleoprotein 40 kDa protein OS=Homo sapiens OX=9606 GN=SNRNP40 PE=1 SV=1 4.21 2210 - 264591 - - - -0.4063 - 2.273 0.566 - 321.6 1 2 0 -0.0006 15 0 0 0 5.85E+06 2.62E+06 - - - 5.24 0.9963 221125_WJC_METTL3_EV_vs_WT_F05.10850.10850.2 1.60E-07 24-Dec K.EPAASAAAFPSQR[166.11].T sp|Q9Y2X9|ZN281_HUMAN 1 1311.6447 1.47 63136 10850 2 1311.636769 656.8296 Zinc finger protein 281 OS=Homo sapiens OX=9606 GN=ZNF281 PE=1 SV=1 6.1 2210.1 - 205540 - - - -6.0344 - 2.327 0.569 - 608.9 1 2 0 -0.0079 13 0 0 0 5.38E+06 3.67E+06 - - - 5.4088 0.9997 221125_WJC_METTL3_EV_vs_WT_F05.10854.10854.3 0.00139 Dec-36 R.QRNEVVVELR.K "sp|O00629|IMA3_HUMAN,tr|A0A7I2YQ95|A0A7I2YQ95_HUMAN,tr|H7C4F6|H7C4F6_HUMAN,tr|A0A7I2V340|A0A7I2V340_HUMAN,tr|A0A7I2V333|A0A7I2V333_HUMAN" 5 1240.6888 1.12 63139 10854 3 1240.68757 414.5702 Importin subunit alpha-3 OS=Homo sapiens OX=9606 GN=KPNA4 PE=1 SV=1 6.14 2210.7 - 1.01E+06 - - - -0.9785 - 2.262 0.407 - 345.1 1 2 1 -0.0012 10 0 0 0 7.68E+06 6.88E+06 - - - 5.4611 0.9874 221125_WJC_METTL3_EV_vs_WT_F05.10856.10856.3 0.0242 Sep-40 K.EGIR[166.11]EETVSLR[166.11].K sp|P20618|PSB1_HUMAN 1 1307.6948 0.85 63140 10856 3 1307.695367 436.9055 Proteasome subunit beta type-1 OS=Homo sapiens OX=9606 GN=PSMB1 PE=1 SV=2 4.79 2210.9 - 3.10E+06 - - - 0.4191 - 1.825 0.212 - 120.1 1 2 1 0.0005 11 0 0 0 2.71E+07 3.20E+07 - - - 2.6124 0.9996 221125_WJC_METTL3_EV_vs_WT_F05.10857.10857.3 0.0105 Nov-48 K.LGHPDTLNQGEFK.E sp|P06702|S10A9_HUMAN 1 1454.7154 74.34 63141 10857 3 1454.715445 485.9124 Protein S100-A9 OS=Homo sapiens OX=9606 GN=S100A9 PE=1 SV=1 5.32 2211 - 2.18E+06 - - - 0.0357 - 1.729 0.361 - 126.3 1 2 0 0.0001 13 0 0 0 1.29E+07 1.74E+05 - - - 4.0493 0.9855 221125_WJC_METTL3_EV_vs_WT_F05.10858.10858.2 0.000476 12-Aug V.PNLHVMK[136.11].A "sp|Q9NQ39|RS10L_HUMAN,sp|P46783|RS10_HUMAN,tr|A0A2R8Y6L3|A0A2R8Y6L3_HUMAN,tr|F6U211|F6U211_HUMAN,tr|A0A1W2PQS6|A0A1W2PQS6_HUMAN,tr|A0A2R8YFH6|A0A2R8YFH6_HUMAN,tr|A0A2R8Y7H1|A0A2R8Y7H1_HUMAN,tr|S4R435|S4R435_HUMAN" 8 845.4673 1.03 63142 10858 2 845.467744 423.7409 Putative 40S ribosomal protein S10-like OS=Homo sapiens OX=9606 GN=RPS10P5 PE=5 SV=1 9.18 2211.1 - 1.57E+06 - - - 0.5323 - 2.007 0.365 - 235 1 1 0 0.0004 7 0 0 0 1.37E+07 1.33E+07 - - - 3.9441 0.999 221125_WJC_METTL3_EV_vs_WT_F05.10859.10859.3 0.0132 Oct-44 K.EAQLYAAQAHLK[136.11].L "sp|P49321|NASP_HUMAN,tr|E9PI86|E9PI86_HUMAN,tr|Q5T624|Q5T624_HUMAN,tr|H0YF33|H0YF33_HUMAN,tr|E9PRH9|E9PRH9_HUMAN" 5 1349.7183 1 63143 10859 3 1349.720034 450.9134 Nuclear autoantigenic sperm protein OS=Homo sapiens OX=9606 GN=NASP PE=1 SV=2 6.85 2211.1 - 1.46E+06 - - - 1.2847 - 1.71 0.31 - 93.5 1 2 0 0.0017 12 0 0 0 1.30E+07 1.30E+07 - - - 3.4828 1 221125_WJC_METTL3_EV_vs_WT_F05.10860.10860.2 1.02E-13 19/28 R.C[160.03]TGGEVGATSALAPK[136.11].L sp|P30050|RL12_HUMAN 1 1425.7013 1.4 63144 10860 2 1425.699257 713.8579 60S ribosomal protein L12 OS=Homo sapiens OX=9606 GN=RPL12 PE=1 SV=1 5.99 2211.2 - 1.13E+06 - - - -1.4533 - 3.466 0.722 - 1363.1 1 2 0 -0.0021 15 0 0 0 2.04E+08 1.46E+08 - - - 7.429 0.9998 221125_WJC_METTL3_EV_vs_WT_F05.10861.10861.2 0.000455 18-Nov R.RLNDFASTVR.L "sp|P20674|COX5A_HUMAN,tr|H3BNX8|H3BNX8_HUMAN,tr|H3BV69|H3BV69_HUMAN,tr|H3BRM5|H3BRM5_HUMAN" 4 1177.6204 1.1 63145 10861 2 1177.620893 589.8175 "Cytochrome c oxidase subunit 5A, mitochondrial OS=Homo sapiens OX=9606 GN=COX5A PE=1 SV=2" 9.6 2211.3 - 970494 - - - 0.4441 - 1.985 0.417 - 227.1 1 2 0 0.0005 10 0 0 0 6.24E+06 5.67E+06 - - - 4.0346 0.9999 221125_WJC_METTL3_EV_vs_WT_F05.10862.10862.2 0.000379 15/22 K.ATEEDSQVPSIR.D sp|Q10472|GALT1_HUMAN 1 1330.6365 2.11 63146 10862 2 1330.636954 666.3255 Polypeptide N-acetylgalactosaminyltransferase 1 OS=Homo sapiens OX=9606 GN=GALNT1 PE=1 SV=1 4.14 2211.4 - 788080 - - - 0.3607 - 2.556 0.447 - 756.7 1 2 0 0.0005 12 0 0 0 1.30E+07 6.19E+06 - - - 4.8116 1 221125_WJC_METTL3_EV_vs_WT_F05.10863.10863.2 5.03E-05 15/28 R.GPQLVC[160.03]TGSDDGTVK.L sp|Q96DI7|SNR40_HUMAN 1 1532.7141 2.27 63147 10863 2 1532.713795 767.3643 U5 small nuclear ribonucleoprotein 40 kDa protein OS=Homo sapiens OX=9606 GN=SNRNP40 PE=1 SV=1 4.21 2211.6 - 583828 - - - -0.1807 - 2.892 0.635 - 804.9 1 2 0 -0.0003 15 0 0 0 5.95E+06 2.62E+06 - - - 6.3419 0.9997 221125_WJC_METTL3_EV_vs_WT_F05.10864.10864.2 0.00783 18-Nov R.R[166.11]LNDFASTVR[166.11].L "sp|P20674|COX5A_HUMAN,tr|H3BNX8|H3BNX8_HUMAN,tr|H3BV69|H3BV69_HUMAN,tr|H3BRM5|H3BRM5_HUMAN" 4 1197.6369 1.16 63148 10864 2 1197.637132 599.8257 "Cytochrome c oxidase subunit 5A, mitochondrial OS=Homo sapiens OX=9606 GN=COX5A PE=1 SV=2" 9.6 2211.7 - 520301 - - - 0.1854 - 2.192 0.341 - 230.8 1 2 0 0.0002 10 0 0 0 6.58E+06 5.67E+06 - - - 3.7502 0.9998 221125_WJC_METTL3_EV_vs_WT_F05.10865.10865.3 0.0217 15/44 K.FTNAVTLQQHVR.M "sp|Q9Y467|SALL2_HUMAN,tr|F5H433|F5H433_HUMAN,tr|E7EW59|E7EW59_HUMAN,tr|H0YFS7|H0YFS7_HUMAN" 4 1412.7524 0.92 63149 10865 3 1412.756279 471.9248 Sal-like protein 2 OS=Homo sapiens OX=9606 GN=SALL2 PE=1 SV=4 9.76 2211.8 - 375550 - - - 2.7124 - 2.538 0.406 - 242.6 1 2 0 0.0038 12 0 0 0 5.07E+06 5.53E+06 - - - 5.6471 0.9996 221125_WJC_METTL3_EV_vs_WT_F05.10866.10866.2 2.50E-08 13/20 K.GAIDHYVTPVK[136.11].A "sp|Q9NX20|RM16_HUMAN,tr|E9PI14|E9PI14_HUMAN" 2 1206.6488 1.82 63150 10866 2 1206.652516 604.3317 "39S ribosomal protein L16, mitochondrial OS=Homo sapiens OX=9606 GN=MRPL16 PE=1 SV=1" 6.74 2211.9 - 315560 - - - 3.0605 - 2.672 0.544 - 611.7 1 2 0 0.0037 11 0 0 0 4.81E+06 2.64E+06 - - - 5.7166 0.9186 221125_WJC_METTL3_EV_vs_WT_F05.10868.10868.2 4.52E-07 14/26 L.AVNAAQDSTDLVAK[136.11].L "sp|P17987|TCPA_HUMAN,tr|F5H282|F5H282_HUMAN,tr|E7EQR6|E7EQR6_HUMAN" 3 1409.7242 0.68 63152 10868 2 1409.729866 705.8694 T-complex protein 1 subunit alpha OS=Homo sapiens OX=9606 GN=TCP1 PE=1 SV=1 4.21 2212.2 - 149674 - - - 4.0384 - 2.68 0.404 - 601.3 1 1 0 0.0057 14 0 0 0 1.05E+06 1.54E+06 - - - 4.497 0.9936 221125_WJC_METTL3_EV_vs_WT_F05.10871.10871.2 2.83E-05 12-Sep V.PNLHVMK.A "sp|Q9NQ39|RS10L_HUMAN,sp|P46783|RS10_HUMAN,tr|A0A2R8Y6L3|A0A2R8Y6L3_HUMAN,tr|F6U211|F6U211_HUMAN,tr|A0A1W2PQS6|A0A1W2PQS6_HUMAN,tr|A0A2R8YFH6|A0A2R8YFH6_HUMAN,tr|A0A2R8Y7H1|A0A2R8Y7H1_HUMAN,tr|S4R435|S4R435_HUMAN" 8 837.4531 1.03 63153 10871 2 837.453516 419.7338 Putative 40S ribosomal protein S10-like OS=Homo sapiens OX=9606 GN=RPS10P5 PE=5 SV=1 9.18 2212.6 - 2.23E+06 - - - 0.5039 - 2.205 0.505 - 272.4 1 1 0 0.0004 7 0 0 0 1.37E+07 1.33E+07 - - - 5.2763 0.9998 221125_WJC_METTL3_EV_vs_WT_F05.10872.10872.3 0.000461 Sep-44 K.EYSGFAGVSRPR.G "sp|Q9NYF8|BCLF1_HUMAN,tr|H0YF63|H0YF63_HUMAN,tr|E9PK91|E9PK91_HUMAN,tr|H0YF14|H0YF14_HUMAN" 4 1324.6524 1.08 63154 10872 3 1324.653911 442.5581 Bcl-2-associated transcription factor 1 OS=Homo sapiens OX=9606 GN=BCLAF1 PE=1 SV=2 8.85 2212.6 - 2.10E+06 - - - 1.1422 - 1.708 0.422 - 106.9 1 2 0 0.0015 12 0 0 0 5.93E+06 5.47E+06 - - - 4.7283 0.9974 221125_WJC_METTL3_EV_vs_WT_F05.10875.10875.2 0.0127 16-Aug K.NVPNLHVMK[136.11].A "sp|Q9NQ39|RS10L_HUMAN,sp|P46783|RS10_HUMAN,tr|A0A2R8Y6L3|A0A2R8Y6L3_HUMAN,tr|F6U211|F6U211_HUMAN,tr|A0A1W2PQS6|A0A1W2PQS6_HUMAN,tr|A0A2R8YFH6|A0A2R8YFH6_HUMAN,tr|A0A2R8Y7H1|A0A2R8Y7H1_HUMAN,tr|S4R435|S4R435_HUMAN" 8 1058.5786 0.65 63157 10875 2 1058.57974 530.2966 Putative 40S ribosomal protein S10-like OS=Homo sapiens OX=9606 GN=RPS10P5 PE=5 SV=1 8.76 2212.9 - 1.03E+06 - - - 1.0439 - 1.243 0.291 - 148.1 1 2 0 0.0011 9 0 0 0 4.25E+06 6.57E+06 - - - 1.8193 0.9989 221125_WJC_METTL3_EV_vs_WT_F05.10876.10876.2 0.0479 18-Aug K.EGNGPVTQWK[136.11].G sp|Q9Y657|SPIN1_HUMAN 1 1122.5549 1.95 63158 10876 2 1122.556208 562.2847 Spindlin-1 OS=Homo sapiens OX=9606 GN=SPIN1 PE=1 SV=3 6.1 2213.1 - 624454 - - - 1.1447 - 1.51 0.33 - 223.3 1 2 0 0.0013 10 0 0 0 2.15E+07 1.10E+07 - - - 2.6283 0.9998 221125_WJC_METTL3_EV_vs_WT_F05.10878.10878.2 0.00994 22-Nov K.ATEEDSQVPSIR[166.11].D sp|Q10472|GALT1_HUMAN 1 1340.6447 2.98 63160 10878 2 1340.644854 671.3296 Polypeptide N-acetylgalactosaminyltransferase 1 OS=Homo sapiens OX=9606 GN=GALNT1 PE=1 SV=1 4.14 2213.3 - 481020 - - - 0.0821 - 2.185 0.37 - 391.7 1 2 0 0.0001 12 0 0 0 1.88E+07 6.32E+06 - - - 3.8303 0.9996 221125_WJC_METTL3_EV_vs_WT_F05.10879.10879.3 0.0919 Nov-44 R.VHQVTPQTHFIS.- "sp|Q9GZP4|PITH1_HUMAN,tr|X6R8S9|X6R8S9_HUMAN" 2 1392.715 - 63161 10879 3 1392.716076 465.2456 PITH domain-containing protein 1 OS=Homo sapiens OX=9606 GN=PITHD1 PE=1 SV=1 6.89 2213.4 - 448350 - - - 0.7733 - 2.203 0.289 - 204.3 1 2 0 0.0011 12 0 0 0 - - - - - 3.951 0.9964 221125_WJC_METTL3_EV_vs_WT_F05.10880.10880.2 0.00475 20-Dec K.EGIREETVSLR.K sp|P20618|PSB1_HUMAN 1 1287.6783 1.08 63162 10880 2 1287.679362 644.8464 Proteasome subunit beta type-1 OS=Homo sapiens OX=9606 GN=PSMB1 PE=1 SV=2 4.79 2213.6 - 372779 - - - 0.841 - 2.582 0.287 - 172.7 1 2 1 0.0011 11 0 0 0 2.22E+06 2.06E+06 - - - 3.7265 0.9998 221125_WJC_METTL3_EV_vs_WT_F05.10881.10881.2 1.28E-05 20-Nov K.MGITEYNNQC[160.03]R.A "sp|P41252|SYIC_HUMAN,tr|A0A804HL54|A0A804HL54_HUMAN,tr|A0A804HKU1|A0A804HKU1_HUMAN,tr|A0A804HK69|A0A804HK69_HUMAN,tr|A0A804HIV9|A0A804HIV9_HUMAN,tr|A0A804HKW6|A0A804HKW6_HUMAN,tr|A0A804HJN6|A0A804HJN6_HUMAN,tr|A0A804HHW9|A0A804HHW9_HUMAN,tr|A0A0A0MSX9|A0A0A0MSX9_HUMAN,tr|J3KR24|J3KR24_HUMAN,tr|A0A804HIG2|A0A804HIG2_HUMAN,tr|A0A804HJ36|A0A804HJ36_HUMAN" 12 1384.5864 0.96 63163 10881 2 1384.589545 693.3005 "Isoleucine--tRNA ligase, cytoplasmic OS=Homo sapiens OX=9606 GN=IARS1 PE=1 SV=2" 5.75 2213.7 - 349096 - - - 2.2938 - 2.295 0.588 - 557.9 1 2 0 0.0032 11 0 0 0 2.71E+06 2.83E+06 - - - 5.6303 0.9998 221125_WJC_METTL3_EV_vs_WT_F05.10884.10884.2 3.73E-06 24-Oct R.GSENGNEGSLLER[166.11].E sp|Q5JSZ5|PRC2B_HUMAN 1 1370.6302 1.61 63166 10884 2 1370.631192 686.3224 Protein PRRC2B OS=Homo sapiens OX=9606 GN=PRRC2B PE=1 SV=2 4.25 2214.1 - 169090 - - - 0.7559 - 2.425 0.454 - 402.8 1 2 0 0.001 13 0 0 0 6.30E+06 3.92E+06 - - - 4.6674 1 221125_WJC_METTL3_EV_vs_WT_F05.10887.10887.3 0.00197 Dec-44 K.EYSGFAGVSR[166.11]PR[166.11].G "sp|Q9NYF8|BCLF1_HUMAN,tr|H0YF63|H0YF63_HUMAN,tr|E9PK91|E9PK91_HUMAN,tr|H0YF14|H0YF14_HUMAN" 4 1344.6689 2.08 63168 10887 3 1344.670094 449.2303 Bcl-2-associated transcription factor 1 OS=Homo sapiens OX=9606 GN=BCLAF1 PE=1 SV=2 8.85 2214.3 - 5.87E+06 - - - 0.8597 - 2.266 0.463 - 252.7 1 2 0 0.0012 12 0 0 0 1.87E+09 9.00E+08 - - - 5.9691 0.9998 221125_WJC_METTL3_EV_vs_WT_F05.10889.10889.2 0.000155 16-Dec R.RPSTFGIPR.L "sp|P78347|GTF2I_HUMAN,tr|A0A494C1K3|A0A494C1K3_HUMAN" 2 1029.572 1.63 63170 10889 2 1029.572572 515.7933 General transcription factor II-I OS=Homo sapiens OX=9606 GN=GTF2I PE=1 SV=2 12 2214.5 - 1.08E+06 - - - 0.5915 - 2.152 0.419 - 298 1 2 0 0.0006 9 0 0 0 1.20E+08 7.36E+07 - - - 4.3528 0.9946 221125_WJC_METTL3_EV_vs_WT_F05.10890.10890.2 0.00137 18-Sep R.SSENPNEVFR.F sp|P45974|UBP5_HUMAN 1 1177.5364 1.57 63171 10890 2 1177.54228 589.7755 Ubiquitin carboxyl-terminal hydrolase 5 OS=Homo sapiens OX=9606 GN=USP5 PE=1 SV=2 4.53 2214.6 - 604079 - - - 5.0224 - 1.855 0.398 - 249.4 1 2 0 0.0059 10 0 0 0 5.23E+06 3.34E+06 - - - 3.7035 0.9999 221125_WJC_METTL3_EV_vs_WT_F05.10891.10891.2 0.0051 13/24 R.GSENGNEGSLLER.E sp|Q5JSZ5|PRC2B_HUMAN 1 1360.6219 1.61 63172 10891 2 1360.621695 681.3182 Protein PRRC2B OS=Homo sapiens OX=9606 GN=PRRC2B PE=1 SV=2 4.25 2214.8 - 504299 - - - -0.1404 - 2.688 0.547 - 644.6 1 2 0 -0.0002 13 0 0 0 6.30E+06 3.92E+06 - - - 5.6189 0.9975 221125_WJC_METTL3_EV_vs_WT_F05.10894.10894.2 0.00166 22-Oct K.SGPSVPVSVQTK[136.11].D sp|Q9Y2W2|WBP11_HUMAN 1 1192.6543 0.22 63175 10894 2 1192.65777 597.3344 WW domain-binding protein 11 OS=Homo sapiens OX=9606 GN=WBP11 PE=1 SV=1 8.47 2215.1 - 339810 - - - 2.9078 - 1.639 0.345 - 241.9 1 2 0 0.0035 12 0 0 0 3.41E+05 1.59E+06 - - - 2.8881 0.9992 221125_WJC_METTL3_EV_vs_WT_F05.10896.10896.2 2.31E-05 18-Oct R.HWGGNVLGPK.S "sp|P62424|RL7A_HUMAN,tr|Q5T8U2|Q5T8U2_HUMAN" 2 1063.5563 1.29 63177 10896 2 1063.559088 532.7854 60S ribosomal protein L7a OS=Homo sapiens OX=9606 GN=RPL7A PE=1 SV=2 8.76 2215.4 - 337433 - - - 2.6092 - 1.771 0.451 - 245.2 1 2 0 0.0028 10 0 0 0 4.54E+06 3.52E+06 - - - 3.9666 0.9999 221125_WJC_METTL3_EV_vs_WT_F05.10897.10897.2 5.99E-07 20-Sep K.MGITEYNNQC[160.03]R[166.11].A "sp|P41252|SYIC_HUMAN,tr|A0A804HL54|A0A804HL54_HUMAN,tr|A0A804HKU1|A0A804HKU1_HUMAN,tr|A0A804HK69|A0A804HK69_HUMAN,tr|A0A804HIV9|A0A804HIV9_HUMAN,tr|A0A804HKW6|A0A804HKW6_HUMAN,tr|A0A804HJN6|A0A804HJN6_HUMAN,tr|A0A804HHW9|A0A804HHW9_HUMAN,tr|A0A0A0MSX9|A0A0A0MSX9_HUMAN,tr|J3KR24|J3KR24_HUMAN,tr|A0A804HIG2|A0A804HIG2_HUMAN,tr|A0A804HJ36|A0A804HJ36_HUMAN" 12 1394.5946 0.96 63178 10897 2 1394.595234 698.3046 "Isoleucine--tRNA ligase, cytoplasmic OS=Homo sapiens OX=9606 GN=IARS1 PE=1 SV=2" 5.75 2215.5 - 328364 - - - 0.4266 - 2.205 0.59 - 441.7 1 2 0 0.0006 11 0 0 0 2.71E+06 2.83E+06 - - - 5.5377 0.9748 221125_WJC_METTL3_EV_vs_WT_F05.10898.10898.2 0.00122 20-Nov S.SGGFSGGSFSR.G "sp|P13645|K1C10_HUMAN,tr|A0A1B0GVI3|A0A1B0GVI3_HUMAN" 2 1044.4625 30.47 63179 10898 2 1044.464252 523.2385 "Keratin, type I cytoskeletal 10 OS=Homo sapiens OX=9606 GN=KRT10 PE=1 SV=6" 9.47 2215.7 - 1.09E+06 - - - 1.7042 - 1.771 0.454 - 281.4 1 1 0 0.0018 11 0 0 0 2.36E+06 7.76E+04 - - - 3.9398 0.9852 221125_WJC_METTL3_EV_vs_WT_F05.10901.10901.2 2.10E-06 30-Aug K.PGPPQPAAAPEGQDLR.D sp|Q96HA1|P121A_HUMAN 1 1599.8005 2.42 63182 10901 2 1599.802973 800.9075 Nuclear envelope pore membrane protein POM 121 OS=Homo sapiens OX=9606 GN=POM121 PE=1 SV=2 4.37 2216 - 174184 - - - 1.5339 - 1.981 0.521 - 144.1 1 1 0 0.0025 16 0 0 0 1.59E+06 6.57E+05 - - - 4.569 0.9989 221125_WJC_METTL3_EV_vs_WT_F05.10903.10903.2 0.0208 22-Oct K.EIQEPDPTYEEK.M sp|O60264|SMCA5_HUMAN 1 1476.662 0.96 63184 10903 2 1476.666301 739.3383 SWI\SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A member 5 OS=Homo sapiens OX=9606 GN=SMARCA5 PE=1 SV=1 3.91 2216.3 - 160025 - - - 2.8991 - 2.04 0.383 - 261.2 1 2 0 0.0043 12 0 0 0 1.06E+07 1.11E+07 - - - 3.7444 0.9997 221125_WJC_METTL3_EV_vs_WT_F05.10904.10904.2 4.36E-05 20-Aug K.EGFDSISSSSK.E "sp|Q8WTW3|COG1_HUMAN,tr|E9PBL8|E9PBL8_HUMAN,tr|A0A087WVI0|A0A087WVI0_HUMAN" 3 1142.5091 1.07 63185 10904 2 1142.507082 572.2619 Conserved oligomeric Golgi complex subunit 1 OS=Homo sapiens OX=9606 GN=COG1 PE=1 SV=1 4.37 2216.4 - 133921 - - - -1.8083 - 1.608 0.557 - 165.1 1 2 0 -0.0021 11 0 0 0 2.24E+06 2.09E+06 - - - 4.4393 0.9987 221125_WJC_METTL3_EV_vs_WT_F05.10907.10907.3 0.00467 Nov-40 K.EGIREETVSLR.K sp|P20618|PSB1_HUMAN 1 1287.6783 0.85 63187 10907 3 1287.679489 430.2334 Proteasome subunit beta type-1 OS=Homo sapiens OX=9606 GN=PSMB1 PE=1 SV=2 4.79 2216.8 - 3.57E+06 - - - 0.9397 - 1.839 0.364 - 187.6 1 2 1 0.0012 11 0 0 0 2.64E+07 3.11E+07 - - - 4.3286 0.9975 221125_WJC_METTL3_EV_vs_WT_F05.10909.10909.2 0.00708 12-Jul K.SSFSITR.E "sp|Q9Y2W1|TR150_HUMAN,tr|A0A3B3ITZ9|A0A3B3ITZ9_HUMAN" 2 796.4079 2.02 63189 10909 2 796.407965 399.2112 Thyroid hormone receptor-associated protein 3 OS=Homo sapiens OX=9606 GN=THRAP3 PE=1 SV=2 9.47 2217 - 6.64E+06 - - - 0.059 - 1.46 0.188 - 223.6 1 2 0 0 7 0 0 0 4.59E+07 2.27E+07 - - - 1.6287 0.9981 221125_WJC_METTL3_EV_vs_WT_F05.10911.10911.3 0.23 Oct-36 K.QTDVGITHFR[166.11].S sp|Q6P2Q9|PRP8_HUMAN 1 1182.6021 2.4 63191 10911 3 1182.601728 395.208 Pre-mRNA-processing-splicing factor 8 OS=Homo sapiens OX=9606 GN=PRPF8 PE=1 SV=2 6.74 2217 - 5.06E+06 - - - -0.307 - 2.197 0.183 - 207.3 1 2 0 -0.0004 10 0 0 0 1.05E+08 4.37E+07 - - - 2.8788 0.9987 221125_WJC_METTL3_EV_vs_WT_F05.10912.10912.2 0.0195 22-Sep K.EYSGFAGVSRPR.G "sp|Q9NYF8|BCLF1_HUMAN,tr|H0YF63|H0YF63_HUMAN,tr|E9PK91|E9PK91_HUMAN,tr|H0YF14|H0YF14_HUMAN" 4 1324.6524 2.1 63192 10912 2 1324.652371 663.3335 Bcl-2-associated transcription factor 1 OS=Homo sapiens OX=9606 GN=BCLAF1 PE=1 SV=2 8.85 2217.1 - 2.44E+06 - - - -0.0204 - 1.632 0.248 - 84.9 1 2 0 0 12 0 0 0 1.86E+08 8.86E+07 - - - 2.1615 0.9975 221125_WJC_METTL3_EV_vs_WT_F05.10913.10913.2 0.00626 18-Nov R.EKLQEEMLQR.E "sp|P08670|VIME_HUMAN,tr|B0YJC4|B0YJC4_HUMAN" 2 1302.6602 2.1 63193 10913 2 1302.660895 652.3374 Vimentin OS=Homo sapiens OX=9606 GN=VIM PE=1 SV=4 4.79 2217.2 - 1.92E+06 - - - 0.5443 - 2.048 0.406 - 527.5 1 2 1 0.0007 10 0 0 0 6.34E+07 3.01E+07 - - - 4.0405 1 221125_WJC_METTL3_EV_vs_WT_F05.10914.10914.2 1.18E-08 13/22 N.SGYTQSQFSAPR[166.11].D "sp|Q14444|CAPR1_HUMAN,tr|G3V153|G3V153_HUMAN" 2 1337.6239 0.7 63194 10914 2 1337.624479 669.8193 Caprin-1 OS=Homo sapiens OX=9606 GN=CAPRIN1 PE=1 SV=2 8.46 2217.3 - 1.71E+06 - - - 0.3962 - 2.541 0.661 - 523.5 1 1 0 0.0005 12 0 0 0 1.76E+07 2.52E+07 - - - 6.3767 1 221125_WJC_METTL3_EV_vs_WT_F05.10915.10915.3 1.04E-06 18/48 R.KETPPPLVPPAAR.E sp|Q9BQA1|MEP50_HUMAN 1 1371.7874 3.3 63195 10915 3 1371.787704 458.2698 Methylosome protein 50 OS=Homo sapiens OX=9606 GN=WDR77 PE=1 SV=1 8.75 2217.3 - 1.65E+06 - - - 0.1961 - 2.92 0.457 - 534.3 1 2 0 0.0003 13 0 0 0 1.28E+08 3.87E+07 - - - 6.5404 0.9999 221125_WJC_METTL3_EV_vs_WT_F05.10916.10916.3 0.000323 Dec-44 K.TVFAEHISDEC[160.03]K[136.11].R "sp|P39023|RL3_HUMAN,tr|G5E9G0|G5E9G0_HUMAN,tr|H7C3M2|H7C3M2_HUMAN,tr|F8WCR1|F8WCR1_HUMAN,tr|B5MCW2|B5MCW2_HUMAN,tr|H7C422|H7C422_HUMAN" 6 1442.6591 0.36 63196 10916 3 1442.658085 481.8937 60S ribosomal protein L3 OS=Homo sapiens OX=9606 GN=RPL3 PE=1 SV=2 4.65 2217.5 - 765233 - - - -0.7244 - 2.189 0.455 - 134.2 1 2 0 -0.001 12 0 0 0 3.02E+06 8.36E+06 - - - 5.7841 0.9977 221125_WJC_METTL3_EV_vs_WT_F05.10917.10917.2 0.246 16-Aug R.LQLEIDQKK.D "sp|Q9Y266|NUDC_HUMAN,tr|A0A0A0MSS4|A0A0A0MSS4_HUMAN,tr|A0A0A0MSU9|A0A0A0MSU9_HUMAN" 3 1113.6394 2.1 63197 10917 2 1113.639358 557.827 Nuclear migration protein nudC OS=Homo sapiens OX=9606 GN=NUDC PE=1 SV=1 6.07 2217.6 - 651738 - - - -0.0144 - 1.459 0.209 - 197 1 2 0 0 9 0 0 0 8.10E+06 3.85E+06 - - - 1.6775 1 221125_WJC_METTL3_EV_vs_WT_F05.10919.10919.3 2.07E-07 17/48 K.NPLPPSVGVVDK[136.11]K[136.11].E sp|Q8NC51|PAIRB_HUMAN 1 1364.7999 1.01 63199 10919 3 1364.800772 455.9406 Plasminogen activator inhibitor 1 RNA-binding protein OS=Homo sapiens OX=9606 GN=SERBP1 PE=1 SV=2 8.59 2217.8 - 584268 - - - 0.6748 - 2.842 0.485 - 394.3 1 2 0 0.0009 13 0 0 0 1.78E+07 1.77E+07 - - - 6.779 1 221125_WJC_METTL3_EV_vs_WT_F05.10922.10922.3 3.27E-06 14/44 K.TVFAEHISDEC[160.03]K.R "sp|P39023|RL3_HUMAN,tr|G5E9G0|G5E9G0_HUMAN,tr|H7C3M2|H7C3M2_HUMAN,tr|F8WCR1|F8WCR1_HUMAN,tr|B5MCW2|B5MCW2_HUMAN,tr|H7C422|H7C422_HUMAN" 6 1434.6449 0.35 63202 10922 3 1434.644405 479.2223 60S ribosomal protein L3 OS=Homo sapiens OX=9606 GN=RPL3 PE=1 SV=2 4.65 2218.2 - 471133 - - - -0.3659 - 2.334 0.526 - 222.6 1 2 0 -0.0005 12 0 0 0 3.02E+06 8.60E+06 - - - 6.7536 0.9986 221125_WJC_METTL3_EV_vs_WT_F05.10923.10923.2 4.13E-05 18-Nov K.QTDVGITHFR.S sp|Q6P2Q9|PRP8_HUMAN 1 1172.5938 1.93 63203 10923 2 1172.59741 587.3042 Pre-mRNA-processing-splicing factor 8 OS=Homo sapiens OX=9606 GN=PRPF8 PE=1 SV=2 6.74 2218.4 - 464399 - - - 3.0607 - 2.108 0.342 - 523.1 1 2 0 0.0036 10 0 0 0 9.29E+06 4.81E+06 - - - 3.6475 0.9999 221125_WJC_METTL3_EV_vs_WT_F05.10926.10926.2 4.89E-05 14/30 K.AISSASSPQSPGDALR[166.11].R sp|Q96KR1|ZFR_HUMAN 1 1552.7721 1.12 63206 10926 2 1552.77124 777.3933 Zinc finger RNA-binding protein OS=Homo sapiens OX=9606 GN=ZFR PE=1 SV=2 5.88 2218.8 - 387398 - - - -0.5339 - 2.554 0.499 - 486.2 1 2 0 -0.0008 16 0 0 0 7.82E+06 6.97E+06 - - - 5.0316 0.9999 221125_WJC_METTL3_EV_vs_WT_F05.10930.10930.3 0.00897 14/44 K.LHGVNINVEASK.N "sp|Q9BWF3|RBM4_HUMAN,sp|Q9BQ04|RBM4B_HUMAN,tr|E9PM61|E9PM61_HUMAN,tr|D6R9K7|D6R9K7_HUMAN,tr|J3QRR5|J3QRR5_HUMAN,tr|E9PB51|E9PB51_HUMAN,tr|U3KQD5|U3KQD5_HUMAN,tr|E9PLB0|E9PLB0_HUMAN" 8 1279.6885 2.01 63209 10930 3 1279.688938 427.5701 RNA-binding protein 4 OS=Homo sapiens OX=9606 GN=RBM4 PE=1 SV=1 6.75 2219.1 - 2.38E+06 - - - 0.3813 - 2.73 0.357 - 423.3 1 2 0 0.0005 12 0 0 0 1.14E+08 5.68E+07 - - - 5.3038 0.9997 221125_WJC_METTL3_EV_vs_WT_F05.10932.10932.2 2.14E-05 22-Dec K.EIQEPDPTYEEK[136.11].M sp|O60264|SMCA5_HUMAN 1 1484.6762 0.96 63211 10932 2 1484.67659 743.3454 SWI\SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A member 5 OS=Homo sapiens OX=9606 GN=SMARCA5 PE=1 SV=1 3.91 2219.3 - 735208 - - - 0.2492 - 2.042 0.38 - 412.8 1 2 0 0.0004 12 0 0 0 1.06E+07 1.11E+07 - - - 3.726 0.9997 221125_WJC_METTL3_EV_vs_WT_F05.10933.10933.3 0.000183 Nov-48 K.LTDC[160.03]VVMR[166.11]DPASK[136.11].R "sp|P22626|ROA2_HUMAN,tr|A0A7I2YQN4|A0A7I2YQN4_HUMAN,tr|A0A7I2V4N0|A0A7I2V4N0_HUMAN,tr|A0A7I2V4N1|A0A7I2V4N1_HUMAN,tr|A0A7I2V4I6|A0A7I2V4I6_HUMAN,tr|A0A087WUI2|A0A087WUI2_HUMAN,tr|A0A7I2V4S4|A0A7I2V4S4_HUMAN,tr|A0A7I2V323|A0A7I2V323_HUMAN,tr|A0A7I2V3P1|A0A7I2V3P1_HUMAN,tr|A0A7I2V3P7|A0A7I2V3P7_HUMAN" 10 1508.7446 1.07 63212 10933 3 1508.744511 503.9221 Heterogeneous nuclear ribonucleoproteins A2\B1 OS=Homo sapiens OX=9606 GN=HNRNPA2B1 PE=1 SV=2 5.95 2219.5 - 686672 - - - -0.0623 - 2.104 0.441 - 193 1 2 1 -0.0001 13 0 0 0 5.70E+07 5.31E+07 - - - 5.4735 0.9997 221125_WJC_METTL3_EV_vs_WT_F05.10934.10934.3 0.000201 Oct-44 K.EYSGFAGVSR[166.11]PR.G "sp|Q9NYF8|BCLF1_HUMAN,tr|H0YF63|H0YF63_HUMAN,tr|E9PK91|E9PK91_HUMAN,tr|H0YF14|H0YF14_HUMAN" 4 1334.6607 - 63213 10934 3 1334.657396 445.8942 Bcl-2-associated transcription factor 1 OS=Homo sapiens OX=9606 GN=BCLAF1 PE=1 SV=2 8.85 2219.5 - 621045 - - - -2.4516 - 1.866 0.426 - 124.2 1 2 0 -0.0033 12 0 0 0 - - - - - 5.0176 0.9998 221125_WJC_METTL3_EV_vs_WT_F05.10935.10935.2 0.00893 16-Oct K.KLNEILQAR.G "sp|Q99613|EIF3C_HUMAN,sp|B5ME19|EIFCL_HUMAN" 2 1083.64 1.22 63214 10935 2 1083.638856 542.8273 Eukaryotic translation initiation factor 3 subunit C OS=Homo sapiens OX=9606 GN=EIF3C PE=1 SV=1 8.75 2219.7 - 610239 - - - -1.0954 - 2.028 0.406 - 422.6 1 2 0 -0.0012 9 0 0 0 3.42E+06 2.80E+06 - - - 4.0849 0.9851 221125_WJC_METTL3_EV_vs_WT_F05.10938.10938.2 0.00211 20-Nov E.YSGFAGVSR[166.11]PR[166.11].G "sp|Q9NYF8|BCLF1_HUMAN,tr|H0YF63|H0YF63_HUMAN,tr|E9PK91|E9PK91_HUMAN,tr|H0YF14|H0YF14_HUMAN" 4 1215.6263 2.5 63217 10938 2 1215.626162 608.8204 Bcl-2-associated transcription factor 1 OS=Homo sapiens OX=9606 GN=BCLAF1 PE=1 SV=2 10.84 2220.1 - 348436 - - - -0.1505 - 1.78 0.43 - 173.4 1 1 0 -0.0002 11 0 0 0 2.36E+07 9.46E+06 - - - 3.7768 0.9994 221125_WJC_METTL3_EV_vs_WT_F05.10939.10939.2 3.91E-07 24-Dec K.TVNQQTMAAPVVK[136.11].E "sp|Q9Y520|PRC2C_HUMAN,tr|E7EPN9|E7EPN9_HUMAN" 2 1393.7479 1.07 63218 10939 2 1393.752865 697.8812 Protein PRRC2C OS=Homo sapiens OX=9606 GN=PRRC2C PE=1 SV=4 8.41 2220.2 - 347076 - - - 3.5731 - 2.44 0.576 - 485.4 1 2 0 0.005 13 0 0 0 6.74E+06 6.32E+06 - - - 5.5831 0.8904 221125_WJC_METTL3_EV_vs_WT_F05.10940.10940.2 0.483 20-Jul K.IAHLAQIEDDR.A "sp|A6NHR9|SMHD1_HUMAN,tr|A0A2R8YCU7|A0A2R8YCU7_HUMAN,tr|J3KTL8|J3KTL8_HUMAN" 3 1279.6521 -1 63219 10940 2 1279.6472 640.8333 Structural maintenance of chromosomes flexible hinge domain-containing protein 1 OS=Homo sapiens OX=9606 GN=SMCHD1 PE=1 SV=2 4.54 2220.3 - 344619 - - - -3.801 - 1.168 0.12 - 105.7 1 2 0 -0.0049 11 0 0 0 0.00E+00 0.00E+00 - - - 0.3459 0.9839 221125_WJC_METTL3_EV_vs_WT_F05.10943.10943.2 0.000536 16-Nov S.GFAGVSR[166.11]PR[166.11].G "sp|Q9NYF8|BCLF1_HUMAN,tr|H0YF63|H0YF63_HUMAN,tr|E9PK91|E9PK91_HUMAN,tr|H0YF14|H0YF14_HUMAN" 4 965.531 2.11 63220 10943 2 965.530899 483.7728 Bcl-2-associated transcription factor 1 OS=Homo sapiens OX=9606 GN=BCLAF1 PE=1 SV=2 12 2220.7 - 1.22E+06 - - - -0.0922 - 1.63 0.437 - 319.4 1 1 0 -0.0001 9 0 0 0 4.83E+07 2.29E+07 - - - 3.6821 1 221125_WJC_METTL3_EV_vs_WT_F05.10944.10944.3 9.83E-08 19/48 R.K[136.11]ETPPPLVPPAAR[166.11].E sp|Q9BQA1|MEP50_HUMAN 1 1389.8099 3.32 63221 10944 3 1389.807994 464.2772 Methylosome protein 50 OS=Homo sapiens OX=9606 GN=WDR77 PE=1 SV=1 8.75 2220.8 - 1.59E+06 - - - -1.375 - 3.25 0.443 - 584.8 1 2 0 -0.0019 13 0 0 0 1.27E+08 3.83E+07 - - - 6.6742 0.955 221125_WJC_METTL3_EV_vs_WT_F05.10945.10945.3 0.000922 Oct-32 Y.QPYNKDWIK.E sp|P84090|ERH_HUMAN 1 1190.6084 2.14 63222 10945 3 1190.607302 397.8767 Enhancer of rudimentary homolog OS=Homo sapiens OX=9606 GN=ERH PE=1 SV=1 8.5 2220.8 - 4.79E+06 - - - -0.9289 - 1.96 0.417 - 173.9 1 1 1 -0.0011 9 0 0 0 6.66E+07 3.10E+07 - - - 5.2169 0.9996 221125_WJC_METTL3_EV_vs_WT_F05.10946.10946.2 0.00679 16-Sep R.TLSDYNIQK.E "sp|P62979|RS27A_HUMAN,sp|P0CG48|UBC_HUMAN,sp|P0CG48|UBC_HUMAN,sp|P0CG48|UBC_HUMAN,sp|P0CG48|UBC_HUMAN,sp|P0CG48|UBC_HUMAN,sp|P0CG48|UBC_HUMAN,sp|P0CG48|UBC_HUMAN,sp|P0CG48|UBC_HUMAN,sp|P0CG48|UBC_HUMAN,sp|P0CG47|UBB_HUMAN,sp|P0CG47|UBB_HUMAN,sp|P0CG47|UBB_HUMAN,sp|P62987|RL40_HUMAN,tr|F5H388|F5H388_HUMAN,tr|F5H388|F5H388_HUMAN,tr|F5GYU3|F5GYU3_HUMAN,tr|B4DV12|B4DV12_HUMAN,tr|B4DV12|B4DV12_HUMAN,tr|Q5PY61|Q5PY61_HUMAN,tr|Q5PY61|Q5PY61_HUMAN,tr|Q5PY61|Q5PY61_HUMAN,tr|F5H2Z3|F5H2Z3_HUMAN,tr|M0R2S1|M0R2S1_HUMAN,tr|J3QS39|J3QS39_HUMAN,tr|J3QTR3|J3QTR3_HUMAN,tr|Q96C32|Q96C32_HUMAN,tr|Q96C32|Q96C32_HUMAN,tr|Q96C32|Q96C32_HUMAN,tr|Q96C32|Q96C32_HUMAN,tr|M0R1V7|M0R1V7_HUMAN,tr|F5H747|F5H747_HUMAN,tr|F5H747|F5H747_HUMAN,tr|F5GXK7|F5GXK7_HUMAN,tr|F5GXK7|F5GXK7_HUMAN,tr|M0R1M6|M0R1M6_HUMAN,tr|F5H6Q2|F5H6Q2_HUMAN,tr|J3QKN0|J3QKN0_HUMAN,tr|J3QKN0|J3QKN0_HUMAN,tr|F5H265|F5H265_HUMAN,tr|F5H265|F5H265_HUMAN,tr|A0A2R8Y422|A0A2R8Y422_HUMAN" 42 1080.5451 0.56 63223 10946 2 1080.543617 541.2798 Ubiquitin-40S ribosomal protein S27a OS=Homo sapiens OX=9606 GN=RPS27A PE=1 SV=2 5.5 2221 - 854193 - - - -1.4085 - 1.619 0.435 - 154.6 1 2 0 -0.0015 9 0 0 0 2.69E+07 4.81E+07 - - - 3.6473 0.9073 221125_WJC_METTL3_EV_vs_WT_F05.10947.10947.3 0.0036 Sep-40 L.GLDHMASSIER.M "sp|P52272|HNRPM_HUMAN,tr|A0A087X0X3|A0A087X0X3_HUMAN,tr|M0QZM1|M0QZM1_HUMAN" 3 1214.5714 1.87 63224 10947 3 1214.567552 405.8644 Heterogeneous nuclear ribonucleoprotein M OS=Homo sapiens OX=9606 GN=HNRNPM PE=1 SV=3 5.32 2221 - 823971 - - - -3.1443 - 1.601 0.409 - 101.9 1 1 0 -0.0038 11 0 0 0 5.27E+06 2.82E+06 - - - 4.4359 0.9999 221125_WJC_METTL3_EV_vs_WT_F05.10948.10948.2 2.07E-05 15/22 K.LHGVNINVEASK.N "sp|Q9BWF3|RBM4_HUMAN,sp|Q9BQ04|RBM4B_HUMAN,tr|E9PM61|E9PM61_HUMAN,tr|D6R9K7|D6R9K7_HUMAN,tr|J3QRR5|J3QRR5_HUMAN,tr|E9PB51|E9PB51_HUMAN,tr|U3KQD5|U3KQD5_HUMAN,tr|E9PLB0|E9PLB0_HUMAN" 8 1279.6885 1.63 63225 10948 2 1279.689835 640.8515 RNA-binding protein 4 OS=Homo sapiens OX=9606 GN=RBM4 PE=1 SV=1 6.75 2221.2 - 606950 - - - 1.0823 - 2.544 0.517 - 699.3 1 2 0 0.0014 12 0 0 0 1.21E+07 7.42E+06 - - - 5.3159 0.9998 221125_WJC_METTL3_EV_vs_WT_F05.10949.10949.2 0.00412 20-Dec R.QLQLAQEAAQK.R sp|Q15149|PLEC_HUMAN 1 1226.6619 1.91 63226 10949 2 1226.66259 614.3382 Plectin OS=Homo sapiens OX=9606 GN=PLEC PE=1 SV=3 6 2221.3 - 326756 - - - 0.5625 - 2.249 0.444 - 671.1 1 2 0 0.0007 11 0 0 0 8.91E+06 4.65E+06 - - - 4.5127 0.997 221125_WJC_METTL3_EV_vs_WT_F05.10950.10950.2 0.00506 18-Aug R.HWGGNVLGPK[136.11].S "sp|P62424|RL7A_HUMAN,tr|Q5T8U2|Q5T8U2_HUMAN" 2 1071.5705 1.29 63227 10950 2 1071.567777 536.7925 60S ribosomal protein L7a OS=Homo sapiens OX=9606 GN=RPL7A PE=1 SV=2 8.76 2221.4 - 306183 - - - -2.5533 - 1.184 0.394 - 168.3 1 2 0 -0.0027 10 0 0 0 4.54E+06 3.52E+06 - - - 2.4217 0.9989 221125_WJC_METTL3_EV_vs_WT_F05.10953.10953.2 0.0553 20-Sep R.QLQLAQEAAQK[136.11].R sp|Q15149|PLEC_HUMAN 1 1234.6761 1.91 63230 10953 2 1234.676485 618.3453 Plectin OS=Homo sapiens OX=9606 GN=PLEC PE=1 SV=3 6 2221.8 - 200369 - - - 0.3118 - 2.022 0.188 - 311 1 2 0 0.0004 11 0 0 0 8.91E+06 4.65E+06 - - - 2.3342 0.9994 221125_WJC_METTL3_EV_vs_WT_F05.10954.10954.2 1.92E-06 28-Sep R.GDTVSASPC[160.03]SAPLAR[166.11].A sp|Q15477|SKIV2_HUMAN 1 1497.7121 1.45 63231 10954 2 1497.706919 749.8633 Helicase SKI2W OS=Homo sapiens OX=9606 GN=SKIV2L PE=1 SV=3 5.83 2221.9 - 196003 - - - -3.4673 - 1.93 0.62 - 200.4 1 2 0 -0.0052 15 0 0 0 1.09E+07 7.52E+06 - - - 5.2352 0.9998 221125_WJC_METTL3_EV_vs_WT_F05.10957.10957.3 0.0023 Nov-40 R.AMGEQLLPGKK.F "sp|Q14671|PUM1_HUMAN,tr|Q5T1Z8|Q5T1Z8_HUMAN,tr|H0YEH2|H0YEH2_HUMAN,tr|Q5T1Z4|Q5T1Z4_HUMAN" 4 1170.6431 2.33 63232 10957 3 1170.641291 391.2216 Pumilio homolog 1 OS=Homo sapiens OX=9606 GN=PUM1 PE=1 SV=3 8.64 2222.3 - 4.99E+06 - - - -1.5274 - 1.868 0.401 - 137.3 1 2 0 -0.0018 11 0 0 0 1.37E+08 5.91E+07 - - - 4.7854 0.9994 221125_WJC_METTL3_EV_vs_WT_F05.10959.10959.3 0.00035 Sep-48 K.LTDC[160.03]VVMRDPASK.R "sp|P22626|ROA2_HUMAN,tr|A0A7I2YQN4|A0A7I2YQN4_HUMAN,tr|A0A7I2V4N0|A0A7I2V4N0_HUMAN,tr|A0A7I2V4N1|A0A7I2V4N1_HUMAN,tr|A0A7I2V4I6|A0A7I2V4I6_HUMAN,tr|A0A087WUI2|A0A087WUI2_HUMAN,tr|A0A7I2V4S4|A0A7I2V4S4_HUMAN,tr|A0A7I2V323|A0A7I2V323_HUMAN,tr|A0A7I2V3P1|A0A7I2V3P1_HUMAN,tr|A0A7I2V3P7|A0A7I2V3P7_HUMAN" 10 1490.7221 1.07 63234 10959 3 1490.721034 497.9147 Heterogeneous nuclear ribonucleoproteins A2\B1 OS=Homo sapiens OX=9606 GN=HNRNPA2B1 PE=1 SV=2 5.95 2222.5 - 1.39E+06 - - - -0.7386 - 2.115 0.391 - 120.3 1 2 1 -0.0011 13 0 0 0 5.70E+07 5.31E+07 - - - 4.9299 0.9997 221125_WJC_METTL3_EV_vs_WT_F05.10960.10960.2 1.96E-06 13/24 R.KETPPPLVPPAAR.E sp|Q9BQA1|MEP50_HUMAN 1 1371.7874 4.98 63235 10960 2 1371.786763 686.901 Methylosome protein 50 OS=Homo sapiens OX=9606 GN=WDR77 PE=1 SV=1 8.75 2222.6 - 614058 - - - -0.4899 - 2.28 0.357 - 528.9 1 2 0 -0.0007 13 0 0 0 1.19E+07 2.39E+06 - - - 3.7929 0.9998 221125_WJC_METTL3_EV_vs_WT_F05.10961.10961.2 0.00105 20-Dec R.AMGEQLLPGKK.F "sp|Q14671|PUM1_HUMAN,tr|Q5T1Z8|Q5T1Z8_HUMAN,tr|H0YEH2|H0YEH2_HUMAN,tr|Q5T1Z4|Q5T1Z4_HUMAN" 4 1170.6431 2.7 63236 10961 2 1170.643166 586.3288 Pumilio homolog 1 OS=Homo sapiens OX=9606 GN=PUM1 PE=1 SV=3 8.64 2222.8 - 602877 - - - 0.0743 - 2.118 0.422 - 440.3 1 2 0 0.0001 11 0 0 0 2.13E+07 7.87E+06 - - - 4.1881 0.9996 221125_WJC_METTL3_EV_vs_WT_F05.10962.10962.2 0.000534 20-Sep K.STVPTDFSSAK.L "sp|Q08722|CD47_HUMAN,tr|A0A2R8Y484|A0A2R8Y484_HUMAN" 2 1138.5506 1.34 63237 10962 2 1138.549579 570.2826 Leukocyte surface antigen CD47 OS=Homo sapiens OX=9606 GN=CD47 PE=1 SV=1 5.55 2222.9 - 513384 - - - -0.9134 - 1.68 0.391 - 261.4 1 2 0 -0.001 11 0 0 0 1.63E+07 1.22E+07 - - - 3.3321 0.9943 221125_WJC_METTL3_EV_vs_WT_F05.10964.10964.2 4.44E-06 20-Nov L.EGNEQFINAAK.L "sp|P07478|TRY2_HUMAN,sp|P35030|TRY3_HUMAN,sp|Q8NHM4|TRY6_HUMAN,sp|P07477|TRY1_HUMAN,tr|E7EQ64|E7EQ64_HUMAN,tr|A0A7P0MNE9|A0A7P0MNE9_HUMAN,tr|A6XMV9|A6XMV9_HUMAN,tr|A0A0J9YYC8|A0A0J9YYC8_HUMAN,tr|A6XMV8|A6XMV8_HUMAN,tr|H0Y8D1|H0Y8D1_HUMAN" 10 1219.5833 999 63239 10964 2 1219.583271 610.7989 Trypsin-2 OS=Homo sapiens OX=9606 GN=PRSS2 PE=1 SV=1 4.53 2223.1 - 355264 - - - -0.0369 - 2.262 0.553 - 471.5 1 1 0 0 11 0 0 0 5.13E+07 0.00E+00 - - - 5.3336 1 221125_WJC_METTL3_EV_vs_WT_F05.10965.10965.2 7.37E-08 28-Dec R.LGTEPTSETQDELQR[166.11].L sp|O15381|NVL_HUMAN 1 1712.8092 1.44 63240 10965 2 1712.808367 857.4119 Nuclear valosin-containing protein-like OS=Homo sapiens OX=9606 GN=NVL PE=1 SV=1 4 2223.3 - 174796 - - - -0.5114 - 2.827 0.628 - 354.3 1 2 0 -0.0009 15 0 0 0 1.25E+07 8.68E+06 - - - 6.2341 0.9996 221125_WJC_METTL3_EV_vs_WT_F05.10969.10969.3 0.000942 Dec-48 K.APGQHGGFVVTVK.Q "sp|Q9P0W2|HM20B_HUMAN,tr|C9J8X5|C9J8X5_HUMAN,tr|C9JQA7|C9JQA7_HUMAN,tr|C9K049|C9K049_HUMAN,tr|B5MDG7|B5MDG7_HUMAN,tr|F8WES5|F8WES5_HUMAN" 6 1295.6986 12.09 63242 10969 3 1295.698125 432.9068 SWI\SNF-related matrix-associated actin-dependent regulator of chromatin subfamily E member 1-related OS=Homo sapiens OX=9606 GN=HMG20B PE=1 SV=1 8.8 2223.8 - 627318 - - - -0.382 - 2.384 0.285 - 140 1 2 0 -0.0005 13 0 0 0 9.43E+06 7.80E+05 - - - 4.0728 0.9978 221125_WJC_METTL3_EV_vs_WT_F05.10970.10970.2 0.00341 18-Aug R.VHIEIGPDGR.V "sp|P55795|HNRH2_HUMAN,sp|P52597|HNRPF_HUMAN,sp|P31943|HNRH1_HUMAN,tr|H0YBD7|H0YBD7_HUMAN,tr|H0YB39|H0YB39_HUMAN,tr|H0YBG7|H0YBG7_HUMAN,tr|E9PCY7|E9PCY7_HUMAN,tr|G8JLB6|G8JLB6_HUMAN" 8 1091.5724 1.17 63243 10970 2 1091.573141 546.7935 Heterogeneous nuclear ribonucleoprotein H2 OS=Homo sapiens OX=9606 GN=HNRNPH2 PE=1 SV=1 5.32 2223.9 - 1.15E+06 - - - 0.7182 - 1.789 0.158 - 216.3 1 2 0 0.0008 10 0 0 0 3.36E+08 2.87E+08 - - - 1.8313 0.9535 221125_WJC_METTL3_EV_vs_WT_F05.10971.10971.3 0.00385 Dec-32 H.QQLYWSHPR[166.11].K "sp|P62273|RS29_HUMAN,tr|A0A2R8Y851|A0A2R8Y851_HUMAN" 2 1223.6075 0.93 63244 10971 3 1223.609365 408.8764 40S ribosomal protein S29 OS=Homo sapiens OX=9606 GN=RPS29 PE=1 SV=2 8.75 2224 - 691042 - - - 1.5152 - 2.076 0.308 - 300.8 1 1 0 0.0019 9 0 0 0 1.35E+07 1.45E+07 - - - 4.1748 0.9999 221125_WJC_METTL3_EV_vs_WT_F05.10972.10972.2 5.26E-08 13/28 R.LGTEPTSETQDELQR.L sp|O15381|NVL_HUMAN 1 1702.801 1.25 63245 10972 2 1702.801587 852.4078 Nuclear valosin-containing protein-like OS=Homo sapiens OX=9606 GN=NVL PE=1 SV=1 4 2224.1 - 337127 - - - 0.3606 - 2.601 0.564 - 415.9 1 2 0 0.0006 15 0 0 0 1.26E+07 1.01E+07 - - - 5.5566 0.999 221125_WJC_METTL3_EV_vs_WT_F05.10973.10973.2 1.04E-05 18-Oct R.YPDGIISK[136.11]PK[136.11].N sp|Q86U44|MTA70_HUMAN 1 1132.6463 0.01 63246 10973 2 1132.642176 567.3304 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 8.5 2224.3 - 263591 - - - -3.6499 - 1.861 0.52 - 297.5 1 2 0 -0.0041 10 0 0 0 5.45E+04 4.35E+06 - - - 4.6141 1 221125_WJC_METTL3_EV_vs_WT_F05.10978.10978.3 4.03E-05 14/44 R.K[136.11]PLLESGTLGTK[136.11].G sp|P22314|UBA1_HUMAN 1 1258.7468 0.63 63249 10978 3 1258.745645 420.5895 Ubiquitin-like modifier-activating enzyme 1 OS=Homo sapiens OX=9606 GN=UBA1 PE=1 SV=3 8.59 2224.9 - 2.10E+06 - - - -0.8802 - 2.744 0.465 - 399.2 1 2 0 -0.0011 12 0 0 0 1.45E+07 2.32E+07 - - - 6.5219 0.9999 221125_WJC_METTL3_EV_vs_WT_F05.10979.10979.3 0.00239 Dec-40 K.QDLPALEEK[136.11]PR[166.11].N "sp|P34932|HSP74_HUMAN,tr|A0A087WTS8|A0A087WTS8_HUMAN,tr|A0A087WYC1|A0A087WYC1_HUMAN" 3 1312.7106 0.1 63250 10979 3 1312.71195 438.5775 Heat shock 70 kDa protein 4 OS=Homo sapiens OX=9606 GN=HSPA4 PE=1 SV=4 4.68 2224.9 - 1.13E+06 - - - 1.0398 - 2.589 0.363 - 347.1 1 2 0 0.0014 11 0 0 0 1.16E+07 1.12E+08 - - - 5.2891 0.9992 221125_WJC_METTL3_EV_vs_WT_F05.10980.10980.2 0.00432 20-Sep K.STVPTDFSSAK[136.11].L "sp|Q08722|CD47_HUMAN,tr|A0A2R8Y484|A0A2R8Y484_HUMAN" 2 1146.5648 1.34 63251 10980 2 1146.563345 574.2897 Leukocyte surface antigen CD47 OS=Homo sapiens OX=9606 GN=CD47 PE=1 SV=1 5.55 2225 - 904304 - - - -1.2856 - 1.627 0.347 - 198 1 2 0 -0.0015 11 0 0 0 1.63E+07 1.22E+07 - - - 2.9202 1 221125_WJC_METTL3_EV_vs_WT_F05.10981.10981.2 3.60E-10 14/22 R.AAEC[160.03]NIVVTQPR.R sp|Q08211|DHX9_HUMAN 1 1356.682 0.9 63252 10981 2 1356.681398 679.3483 ATP-dependent RNA helicase A OS=Homo sapiens OX=9606 GN=DHX9 PE=1 SV=4 6.04 2225.2 - 523890 - - - -0.4319 - 2.98 0.647 - 755.5 1 2 0 -0.0006 12 0 0 0 1.20E+08 1.33E+08 - - - 6.6926 0.9994 221125_WJC_METTL3_EV_vs_WT_F05.10982.10982.2 0.00752 22-Oct K.TEPTSPTPSAFK[136.11].G sp|Q86XN7|PRSR1_HUMAN 1 1269.6332 0.88 63253 10982 2 1269.633364 635.8239 Proline and serine-rich protein 1 OS=Homo sapiens OX=9606 GN=PROSER1 PE=1 SV=2 5.66 2225.3 - 463775 - - - 0.1032 - 1.812 0.311 - 386.5 1 2 0 0.0001 12 0 0 0 4.49E+07 5.11E+07 - - - 2.9021 0.9996 221125_WJC_METTL3_EV_vs_WT_F05.10983.10983.2 0.00193 24-Oct R.AESPSPAPPPGLR.G sp|Q9BUA3|SPNDC_HUMAN 1 1274.6619 4.56 63254 10983 2 1274.660489 638.3382 Spindlin interactor and repressor of chromatin-binding protein OS=Homo sapiens OX=9606 GN=SPINDOC PE=1 SV=3 6.05 2225.4 - 358048 - - - -1.107 - 1.701 0.437 - 264 1 2 0 -0.0014 13 0 0 0 1.09E+07 2.39E+06 - - - 3.6316 1 221125_WJC_METTL3_EV_vs_WT_F05.10984.10984.2 4.22E-08 24-Dec K.TMEPEEEVEDDPK.V sp|O15119|TBX3_HUMAN 1 1546.6345 1.39 63255 10984 2 1546.632371 774.3245 T-box transcription factor TBX3 OS=Homo sapiens OX=9606 GN=TBX3 PE=1 SV=4 3.71 2225.6 - 348014 - - - -1.3662 - 2.412 0.725 - 413.2 1 2 0 -0.0021 13 0 0 0 6.23E+06 4.50E+06 - - - 6.6549 0.9998 221125_WJC_METTL3_EV_vs_WT_F05.10988.10988.2 0.000618 18-Oct R.VHIEIGPDGR[166.11].V "sp|P55795|HNRH2_HUMAN,sp|P52597|HNRPF_HUMAN,sp|P31943|HNRH1_HUMAN,tr|H0YBD7|H0YBD7_HUMAN,tr|H0YB39|H0YB39_HUMAN,tr|H0YBG7|H0YBG7_HUMAN,tr|E9PCY7|E9PCY7_HUMAN,tr|G8JLB6|G8JLB6_HUMAN" 8 1101.5806 1.17 63257 10988 2 1101.579245 551.7976 Heterogeneous nuclear ribonucleoprotein H2 OS=Homo sapiens OX=9606 GN=HNRNPH2 PE=1 SV=1 5.32 2226.1 - 2.97E+06 - - - -1.2546 - 2.107 0.464 - 386.1 1 2 0 -0.0014 10 0 0 0 3.36E+08 2.87E+08 - - - 4.5479 1 221125_WJC_METTL3_EV_vs_WT_F05.10990.10990.2 0.000364 14/22 R.AAEC[160.03]NIVVTQPR[166.11].R sp|Q08211|DHX9_HUMAN 1 1366.6903 0.9 63259 10990 2 1366.688262 684.3524 ATP-dependent RNA helicase A OS=Homo sapiens OX=9606 GN=DHX9 PE=1 SV=4 6.04 2226.3 - 1.60E+06 - - - -1.4575 - 2.744 0.648 - 703.7 1 2 0 -0.002 12 0 0 0 1.20E+08 1.33E+08 - - - 6.4824 1 221125_WJC_METTL3_EV_vs_WT_F05.10994.10994.2 0.00105 13/24 K.TMEPEEEVEDDPK[136.11].V sp|O15119|TBX3_HUMAN 1 1554.6487 1.39 63263 10994 2 1554.644602 778.3316 T-box transcription factor TBX3 OS=Homo sapiens OX=9606 GN=TBX3 PE=1 SV=4 3.71 2226.8 - 331822 - - - -2.6257 - 2.403 0.719 - 447.5 1 2 0 -0.0041 13 0 0 0 6.23E+06 4.50E+06 - - - 6.6004 0.9997 221125_WJC_METTL3_EV_vs_WT_F05.11000.11000.3 0.0359 13/40 K.LAENIDAQLK[136.11]R[166.11].M "sp|P37198|NUP62_HUMAN,tr|M0QXN5|M0QXN5_HUMAN" 2 1287.7266 2.86 63267 11000 3 1287.724023 430.2495 Nuclear pore glycoprotein p62 OS=Homo sapiens OX=9606 GN=NUP62 PE=1 SV=3 6.07 2227.5 - 4.29E+06 - - - -1.9779 - 2.531 0.328 - 373.3 1 2 0 -0.0025 11 0 0 0 1.65E+08 5.78E+07 - - - 4.8342 0.9997 221125_WJC_METTL3_EV_vs_WT_F05.11002.11002.2 0.0536 20-Oct K.LAENIDAQLKR.M "sp|P37198|NUP62_HUMAN,tr|M0QXN5|M0QXN5_HUMAN" 2 1269.7041 2.74 63269 11002 2 1269.703233 635.8593 Nuclear pore glycoprotein p62 OS=Homo sapiens OX=9606 GN=NUP62 PE=1 SV=3 6.07 2227.6 - 843786 - - - -0.6828 - 2.465 0.322 - 456.6 1 2 0 -0.0009 11 0 0 0 1.25E+07 4.55E+06 - - - 3.8597 0.9998 221125_WJC_METTL3_EV_vs_WT_F05.11003.11003.2 9.41E-05 22-Sep K.TEPTSPTPSAFK.G sp|Q86XN7|PRSR1_HUMAN 1 1261.619 0.74 63270 11003 2 1261.619075 631.8168 Proline and serine-rich protein 1 OS=Homo sapiens OX=9606 GN=PROSER1 PE=1 SV=2 5.66 2227.7 - 664125 - - - 0.0333 - 1.792 0.445 - 279.2 1 2 0 0 12 0 0 0 3.02E+07 4.09E+07 - - - 3.8626 0.9998 221125_WJC_METTL3_EV_vs_WT_F05.11004.11004.2 0.00256 20-Nov K.DSGSISLQETR[166.11].R sp|Q9H2G2|SLK_HUMAN 1 1201.5814 0.73 63271 11004 2 1201.58328 601.798 STE20-like serine\threonine-protein kinase OS=Homo sapiens OX=9606 GN=SLK PE=1 SV=1 4.37 2227.9 - 407902 - - - 1.5521 - 2.152 0.474 - 471.6 1 2 0 0.0019 11 0 0 0 3.99E+06 5.45E+06 - - - 4.6147 0.9997 221125_WJC_METTL3_EV_vs_WT_F05.11007.11007.2 1.11E-05 22-Nov R.ESSLDGLGGTGK[136.11].D sp|Q8WUF5|IASPP_HUMAN 1 1127.555 2.05 63274 11007 2 1127.55707 564.7848 RelA-associated inhibitor OS=Homo sapiens OX=9606 GN=PPP1R13L PE=1 SV=4 4.37 2228.3 - 307482 - - - 1.8518 - 2.076 0.508 - 378.1 1 2 0 0.0021 12 0 0 0 2.37E+07 1.16E+07 - - - 4.7144 0.9995 221125_WJC_METTL3_EV_vs_WT_F05.11009.11009.2 3.55E-07 22-Oct K.EYAEDDNIYQQK.L "sp|Q96FW1|OTUB1_HUMAN,tr|F5GYN4|F5GYN4_HUMAN,tr|F5GYJ8|F5GYJ8_HUMAN,tr|J3KR44|J3KR44_HUMAN,tr|F5H6Q1|F5H6Q1_HUMAN" 5 1514.6525 0.67 63276 11009 2 1514.647686 758.3335 Ubiquitin thioesterase OTUB1 OS=Homo sapiens OX=9606 GN=OTUB1 PE=1 SV=2 3.92 2228.5 - 201381 - - - -3.1902 - 1.83 0.637 - 295 1 2 0 -0.0048 12 0 0 0 4.22E+06 6.30E+06 - - - 5.3344 0.9999 221125_WJC_METTL3_EV_vs_WT_F05.11012.11012.2 5.62E-05 20-Sep R.LNQDQLDAVSK.Y "sp|Q14444|CAPR1_HUMAN,tr|G3V153|G3V153_HUMAN,tr|E9PLA9|E9PLA9_HUMAN" 3 1229.6252 0.88 63278 11012 2 1229.625165 615.8199 Caprin-1 OS=Homo sapiens OX=9606 GN=CAPRIN1 PE=1 SV=2 4.21 2228.8 - 2.34E+06 - - - -0.013 - 2.158 0.462 - 245.4 1 2 0 0 11 0 0 0 7.50E+07 8.53E+07 - - - 4.5341 0.9996 221125_WJC_METTL3_EV_vs_WT_F05.11013.11013.3 5.61E-05 Dec-44 K.VDVGK[136.11]DQEFTVK[136.11].S "sp|P21333|FLNA_HUMAN,tr|A0A7P0NMY4|A0A7P0NMY4_HUMAN,tr|Q60FE5|Q60FE5_HUMAN" 3 1379.7267 0.82 63279 11013 3 1379.725648 460.9162 Filamin-A OS=Homo sapiens OX=9606 GN=FLNA PE=1 SV=4 4.56 2228.9 - 1.50E+06 - - - -0.7958 - 2.349 0.408 - 171.1 1 2 1 -0.0011 12 0 0 0 2.95E+07 3.59E+07 - - - 5.4556 0.9997 221125_WJC_METTL3_EV_vs_WT_F05.11017.11017.2 0.000856 14/20 K.LAENIDAQLK[136.11]R[166.11].M "sp|P37198|NUP62_HUMAN,tr|M0QXN5|M0QXN5_HUMAN" 2 1287.7266 2.74 63283 11017 2 1287.728352 644.8706 Nuclear pore glycoprotein p62 OS=Homo sapiens OX=9606 GN=NUP62 PE=1 SV=3 6.07 2229.3 - 520448 - - - 1.3838 - 2.513 0.392 - 947.3 1 2 0 0.0018 11 0 0 0 1.25E+07 4.55E+06 - - - 4.4286 0.999 221125_WJC_METTL3_EV_vs_WT_F05.11021.11021.2 0.00736 20-Oct R.AYTPPEDLQSR.L sp|Q8N5N7|RM50_HUMAN 1 1275.6095 2.27 63285 11021 2 1275.608114 638.812 "39S ribosomal protein L50, mitochondrial OS=Homo sapiens OX=9606 GN=MRPL50 PE=1 SV=2" 4.37 2229.8 - 596328 - - - -1.1108 - 1.624 0.302 - 297.9 1 2 0 -0.0014 11 0 0 0 1.97E+07 8.67E+06 - - - 2.5829 0.987 221125_WJC_METTL3_EV_vs_WT_F05.11024.11024.3 0.663 Jul-52 K.TAVEHATDEDILAK[136.11].G "tr|E9PEM5|E9PEM5_HUMAN,tr|A0A494BZW2|A0A494BZW2_HUMAN,tr|A0A494C1L5|A0A494C1L5_HUMAN,tr|H0YAC6|H0YAC6_HUMAN" 4 1519.761 2.45 63288 11024 3 1519.757959 507.5943 Lipopolysaccharide-responsive and beige-like anchor protein OS=Homo sapiens OX=9606 GN=LRBA PE=1 SV=1 4.31 2230.2 - 270547 - - - -1.9694 - 1.365 0.248 - 34 2 2 0 -0.003 14 0 0 0 1.05E+07 4.29E+06 - - - 1.9917 0.9998 221125_WJC_METTL3_EV_vs_WT_F05.11026.11026.2 0.000203 26-Sep R.ELAGGLEDGEPQQK[136.11].R "sp|Q9BQ52|RNZ2_HUMAN,tr|G5E9D5|G5E9D5_HUMAN,tr|E7ES68|E7ES68_HUMAN" 3 1477.714 0.97 63290 11026 2 1477.713141 739.8643 Zinc phosphodiesterase ELAC protein 2 OS=Homo sapiens OX=9606 GN=ELAC2 PE=1 SV=2 4 2230.4 - 187970 - - - -0.5827 - 1.8 0.487 - 205.9 1 2 0 -0.0009 14 0 0 0 6.66E+06 6.87E+06 - - - 4.1127 1 221125_WJC_METTL3_EV_vs_WT_F05.11028.11028.2 2.79E-07 22-Dec K.GSFSDTGLGDGK.M "sp|Q9Y2W1|TR150_HUMAN,tr|A0A3B3ITZ9|A0A3B3ITZ9_HUMAN" 2 1139.5095 2.33 63291 11028 2 1139.508948 570.762 Thyroid hormone receptor-associated protein 3 OS=Homo sapiens OX=9606 GN=THRAP3 PE=1 SV=2 4.21 2230.7 - 9.64E+06 - - - -0.4686 - 2.291 0.61 - 302 1 2 0 -0.0005 12 0 0 0 1.00E+08 4.31E+07 - - - 5.7275 0.9972 221125_WJC_METTL3_EV_vs_WT_F05.11030.11030.3 0.0364 Aug-40 K.IFQGNVHNFEK[136.11].N "sp|Q96DI7|SNR40_HUMAN,tr|Q9NSS8|Q9NSS8_HUMAN" 2 1339.6764 2.35 63292 11030 3 1339.67505 447.5661 U5 small nuclear ribonucleoprotein 40 kDa protein OS=Homo sapiens OX=9606 GN=SNRNP40 PE=1 SV=1 6.75 2230.9 - 4.23E+06 - - - -1.0338 - 1.487 0.264 - 45.2 1 2 0 -0.0014 11 0 0 0 1.50E+08 6.38E+07 - - - 2.6101 0.9937 221125_WJC_METTL3_EV_vs_WT_F05.11031.11031.3 0.0993 Jun-32 K.FEDENFHYK.H sp|Q08752|PPID_HUMAN 1 1227.5197 1.9 63293 11031 3 1227.517829 410.1805 Peptidyl-prolyl cis-trans isomerase D OS=Homo sapiens OX=9606 GN=PPID PE=1 SV=3 4.65 2231 - 754307 - - - -1.4859 - 1.145 0.296 - 26.5 1 2 0 -0.0018 9 0 0 0 7.88E+06 4.15E+06 - - - 2.2477 0.9999 221125_WJC_METTL3_EV_vs_WT_F05.11035.11035.2 2.50E-07 22-Oct K.EYAEDDNIYQQK[136.11].L "sp|Q96FW1|OTUB1_HUMAN,tr|F5GYN4|F5GYN4_HUMAN,tr|F5GYJ8|F5GYJ8_HUMAN,tr|J3KR44|J3KR44_HUMAN,tr|F5H6Q1|F5H6Q1_HUMAN" 5 1522.6667 0.67 63297 11035 2 1522.664597 762.3406 Ubiquitin thioesterase OTUB1 OS=Homo sapiens OX=9606 GN=OTUB1 PE=1 SV=2 3.92 2231.5 - 450487 - - - -1.393 - 1.933 0.627 - 264.2 1 2 0 -0.0021 12 0 0 0 4.22E+06 6.30E+06 - - - 5.4055 0.9996 221125_WJC_METTL3_EV_vs_WT_F05.11036.11036.2 1.31E-05 13/18 R.THQALGILSK[136.11].T sp|P42166|LAP2A_HUMAN 1 1074.6277 0.85 63298 11036 2 1074.624256 538.3211 "Lamina-associated polypeptide 2, isoform alpha OS=Homo sapiens OX=9606 GN=TMPO PE=1 SV=2" 8.44 2231.6 - 333374 - - - -3.1992 - 2.4 0.555 - 502.4 1 2 0 -0.0034 10 0 0 0 7.44E+06 8.75E+06 - - - 5.5829 0.9995 221125_WJC_METTL3_EV_vs_WT_F05.11043.11043.2 0.0008 20-Aug K.STPVNVPISQK.F sp|Q8WUM4|PDC6I_HUMAN 1 1168.6452 1.23 63303 11043 2 1168.64584 585.3299 Programmed cell death 6-interacting protein OS=Homo sapiens OX=9606 GN=PDCD6IP PE=1 SV=1 8.47 2232.4 - 1.00E+06 - - - 0.5579 - 1.601 0.396 - 175.5 1 2 0 0.0007 11 0 0 0 2.58E+07 2.09E+07 - - - 3.2388 0.9989 221125_WJC_METTL3_EV_vs_WT_F05.11044.11044.2 7.71E-05 20-Sep R.AYTPPEDLQSR[166.11].L sp|Q8N5N7|RM50_HUMAN 1 1285.6178 2.06 63304 11044 2 1285.613567 643.8162 "39S ribosomal protein L50, mitochondrial OS=Homo sapiens OX=9606 GN=MRPL50 PE=1 SV=2" 4.37 2232.5 - 473976 - - - -3.2934 - 1.842 0.456 - 249 1 2 0 -0.0042 11 0 0 0 1.73E+07 8.41E+06 - - - 4.0602 0.9993 221125_WJC_METTL3_EV_vs_WT_F05.11047.11047.3 0.00115 Dec-40 K.QDLPALEEKPR.N "sp|P34932|HSP74_HUMAN,tr|A0A087WTS8|A0A087WTS8_HUMAN,tr|A0A087WYC1|A0A087WYC1_HUMAN" 3 1294.6881 0.09 63307 11047 3 1294.69242 432.57 Heat shock 70 kDa protein 4 OS=Homo sapiens OX=9606 GN=HSPA4 PE=1 SV=4 4.68 2232.9 - 384211 - - - 3.3251 - 2.215 0.359 - 200.7 1 2 0 0.0043 11 0 0 0 8.51E+06 9.63E+07 - - - 4.8005 0.9989 221125_WJC_METTL3_EV_vs_WT_F05.11049.11049.2 1.05E-06 26-Nov R.ELAGGLEDGEPQQK.R "sp|Q9BQ52|RNZ2_HUMAN,tr|G5E9D5|G5E9D5_HUMAN,tr|E7ES68|E7ES68_HUMAN" 3 1469.6998 0.99 63309 11049 2 1469.693838 735.8572 Zinc phosphodiesterase ELAC protein 2 OS=Homo sapiens OX=9606 GN=ELAC2 PE=1 SV=2 4 2233.2 - 290600 - - - -4.058 - 2.158 0.534 - 307.7 1 2 0 -0.006 14 0 0 0 6.78E+06 6.87E+06 - - - 4.9135 0.9226 221125_WJC_METTL3_EV_vs_WT_F05.11052.11052.3 0.0478 Nov-44 R.YMPQNPHIIATK[136.11].T "sp|Q16576|RBBP7_HUMAN,tr|Q5JP01|Q5JP01_HUMAN,tr|E9PC52|E9PC52_HUMAN" 3 1419.7424 1.3 63310 11052 3 1419.737447 474.2547 Histone-binding protein RBBP7 OS=Homo sapiens OX=9606 GN=RBBP7 PE=1 SV=1 8.6 2233.6 - 1.58E+06 - - - -3.4929 - 1.66 0.144 - 111.9 1 2 0 -0.005 12 0 0 0 3.78E+07 2.90E+07 - - - 1.5489 0.9961 221125_WJC_METTL3_EV_vs_WT_F05.11054.11054.2 0.00368 18-Aug R.AVDDGVNTFK[136.11].V sp|P50990|TCPQ_HUMAN 1 1072.528 0.46 63312 11054 2 1072.524584 537.2713 T-complex protein 1 subunit theta OS=Homo sapiens OX=9606 GN=CCT8 PE=1 SV=4 4.21 2233.9 - 636507 - - - -3.2214 - 1.382 0.364 - 156 1 2 0 -0.0035 10 0 0 0 4.96E+06 1.08E+07 - - - 2.6315 0.9997 221125_WJC_METTL3_EV_vs_WT_F05.11057.11057.3 2.60E-07 14/48 K.VLQYYSAATEHDR[166.11].S sp|P42345|MTOR_HUMAN 1 1561.74 0.66 63315 11057 3 1561.733194 521.5873 Serine\threonine-protein kinase mTOR OS=Homo sapiens OX=9606 GN=MTOR PE=1 SV=1 5.32 2234.2 - 343830 - - - -4.3842 - 2.478 0.488 - 195.7 1 2 0 -0.0068 13 0 0 0 3.47E+06 5.30E+06 - - - 6.4392 0.953 221125_WJC_METTL3_EV_vs_WT_F05.11058.11058.2 0.281 14-Aug K.VR[166.11]EFNFEK[136.11].W "sp|P78347|GTF2I_HUMAN,tr|A0A494C1K3|A0A494C1K3_HUMAN" 2 1085.5625 1.61 63316 11058 2 1085.562552 543.7885 General transcription factor II-I OS=Homo sapiens OX=9606 GN=GTF2I PE=1 SV=2 6.11 2234.4 - 303894 - - - 0.0811 - 1.495 0.128 - 190.1 1 2 1 0.0001 8 0 0 0 4.57E+07 2.83E+07 - - - 1.1992 0.9997 221125_WJC_METTL3_EV_vs_WT_F05.11063.11063.3 0.000585 Dec-40 R.KEEELQAALAR.A "sp|Q7Z406|MYH14_HUMAN,sp|P35749|MYH11_HUMAN,sp|P35579|MYH9_HUMAN,tr|A0A0C4DFM8|A0A0C4DFM8_HUMAN" 4 1256.6725 1.11 63319 11063 3 1256.671333 419.8981 Myosin-14 OS=Homo sapiens OX=9606 GN=MYH14 PE=1 SV=2 4.79 2235 - 2.65E+06 - - - -0.9008 - 2.27 0.3 - 349.9 1 2 0 -0.0011 11 0 0 0 9.12E+07 8.25E+07 - - - 4.2132 0.9729 221125_WJC_METTL3_EV_vs_WT_F05.11065.11065.3 0.00229 Nov-52 S.NLPHSGYSDSAVLK.L "sp|P43243|MATR3_HUMAN,tr|B3KM87|B3KM87_HUMAN,tr|A8MXP9|A8MXP9_HUMAN,tr|D6RBK5|D6RBK5_HUMAN,tr|A0A0R4J2E8|A0A0R4J2E8_HUMAN,tr|H0Y8T4|H0Y8T4_HUMAN,tr|D6REM6|D6REM6_HUMAN" 7 1486.7416 1.33 63321 11065 3 1486.740574 496.5878 Matrin-3 OS=Homo sapiens OX=9606 GN=MATR3 PE=1 SV=2 6.74 2235.2 - 932786 - - - -0.6948 - 1.855 0.372 - 121.5 1 1 0 -0.001 14 0 0 0 2.43E+07 1.83E+07 - - - 4.3292 0.9996 221125_WJC_METTL3_EV_vs_WT_F05.11067.11067.2 8.98E-05 22-Sep R.INVYYNESSSQK[136.11].Y "sp|Q9BUF5|TBB6_HUMAN,tr|K7EJZ4|K7EJZ4_HUMAN,tr|K7EQT3|K7EQT3_HUMAN,tr|K7EN98|K7EN98_HUMAN,tr|K7ERA8|K7ERA8_HUMAN,tr|K7ESQ3|K7ESQ3_HUMAN,tr|K7EL29|K7EL29_HUMAN,tr|K7EPE5|K7EPE5_HUMAN,tr|K7EJ64|K7EJ64_HUMAN" 9 1438.682 1.39 63323 11067 2 1438.678155 720.3483 Tubulin beta-6 chain OS=Homo sapiens OX=9606 GN=TUBB6 PE=1 SV=1 6 2235.5 - 217336 - - - -2.6545 - 2.102 0.53 - 219.7 1 2 0 -0.0038 12 0 0 0 3.22E+07 2.31E+07 - - - 4.909 0.9975 221125_WJC_METTL3_EV_vs_WT_F05.11073.11073.2 0.137 16/20 R.K[136.11]EEELQAALAR[166.11].A "sp|Q7Z406|MYH14_HUMAN,sp|P35749|MYH11_HUMAN,sp|P35579|MYH9_HUMAN,tr|A0A0C4DFM8|A0A0C4DFM8_HUMAN" 4 1274.6949 1.33 63327 11073 2 1274.700488 638.3547 Myosin-14 OS=Homo sapiens OX=9606 GN=MYH14 PE=1 SV=2 4.79 2236.2 - 600619 - - - 4.3563 - 2.653 0.327 - 1000.8 1 2 0 0.0056 11 0 0 0 2.34E+07 1.76E+07 - - - 4.094 0.9938 221125_WJC_METTL3_EV_vs_WT_F05.11075.11075.2 0.000252 20-Oct K.ASTNLQDQLEK.T "sp|Q9NUL3|STAU2_HUMAN,tr|E5RJN7|E5RJN7_HUMAN,tr|E7EVJ4|E7EVJ4_HUMAN,tr|E7EVI1|E7EVI1_HUMAN,tr|E7EPX0|E7EPX0_HUMAN,tr|E5RJ67|E5RJ67_HUMAN" 6 1245.6201 1.53 63329 11075 2 1245.626187 623.8173 Double-stranded RNA-binding protein Staufen homolog 2 OS=Homo sapiens OX=9606 GN=STAU2 PE=1 SV=2 4.37 2236.5 - 390253 - - - 4.8907 - 2.1 0.323 - 240.9 1 2 0 0.0061 11 0 0 0 2.24E+07 1.47E+07 - - - 3.4319 0.9996 221125_WJC_METTL3_EV_vs_WT_F05.11076.11076.2 0.000231 24-Aug K.LNQPPEDGISSVK[136.11].F "sp|O43684|BUB3_HUMAN,tr|J3QT28|J3QT28_HUMAN,tr|J3QSX4|J3QSX4_HUMAN" 3 1390.7184 0.42 63330 11076 2 1390.72021 696.3665 Mitotic checkpoint protein BUB3 OS=Homo sapiens OX=9606 GN=BUB3 PE=1 SV=1 4.37 2236.6 - 263931 - - - 1.331 - 1.748 0.446 - 172.8 1 2 0 0.0019 13 0 0 0 1.45E+06 3.46E+06 - - - 3.7679 0.992 221125_WJC_METTL3_EV_vs_WT_F05.11077.11077.2 0.000129 26-Oct R.EVAPDGPLQESSTR.L sp|Q5T1M5|FKB15_HUMAN 1 1484.7107 10.58 63331 11077 2 1484.719197 743.3626 FK506-binding protein 15 OS=Homo sapiens OX=9606 GN=FKBP15 PE=1 SV=2 4.14 2236.8 - 171610 - - - 5.7223 - 1.919 0.424 - 174.5 1 2 0 0.0085 14 0 0 0 2.15E+06 2.03E+05 - - - 3.8057 0.9963 221125_WJC_METTL3_EV_vs_WT_F05.11081.11081.2 0.0189 16-Jun K.EFTAQNLGK[136.11].L "sp|O15372|EIF3H_HUMAN,tr|B3KS98|B3KS98_HUMAN,tr|A0A087WZK9|A0A087WZK9_HUMAN" 3 1014.5226 2.06 63333 11081 2 1014.52489 508.2686 Eukaryotic translation initiation factor 3 subunit H OS=Homo sapiens OX=9606 GN=EIF3H PE=1 SV=1 6.1 2237.3 - 190745 - - - 2.2966 - 1.345 0.302 - 93.2 1 2 0 0.0023 9 0 0 0 6.20E+06 3.01E+06 - - - 2.1283 0.9999 221125_WJC_METTL3_EV_vs_WT_F05.11083.11083.2 3.59E-05 22-Dec K.APSSLSDAVPQR.A "sp|Q8IX01|SUGP2_HUMAN,tr|M0R2Z9|M0R2Z9_HUMAN,tr|M0R3F6|M0R3F6_HUMAN" 3 1226.6255 0.56 63335 11083 2 1226.626536 614.32 SURP and G-patch domain-containing protein 2 OS=Homo sapiens OX=9606 GN=SUGP2 PE=1 SV=2 5.88 2237.5 - 947877 - - - 0.8324 - 2.417 0.525 - 340.4 1 2 0 0.001 12 0 0 0 3.77E+07 6.70E+07 - - - 5.2404 0.9872 221125_WJC_METTL3_EV_vs_WT_F05.11084.11084.2 0.061 20-Oct R.DAPWTASSSEK[136.11].A "sp|Q00341|VIGLN_HUMAN,tr|A0A024R4E5|A0A024R4E5_HUMAN,tr|H7C3D0|H7C3D0_HUMAN,tr|H0Y394|H0Y394_HUMAN" 4 1185.5393 0.98 63336 11084 2 1185.533905 593.7769 Vigilin OS=Homo sapiens OX=9606 GN=HDLBP PE=1 SV=2 4.37 2237.6 - 772707 - - - -4.5777 - 1.403 0.338 - 198.7 1 2 0 -0.0054 11 0 0 0 1.16E+07 1.18E+07 - - - 2.4518 0.9982 221125_WJC_METTL3_EV_vs_WT_F05.11085.11085.3 0.00626 Oct-36 R.RLPENLYNDR.M "sp|P14927|QCR7_HUMAN,tr|E5RHG9|E5RHG9_HUMAN,tr|B7Z2R2|B7Z2R2_HUMAN" 3 1288.6524 1.18 63337 11085 3 1288.649802 430.5581 Cytochrome b-c1 complex subunit 7 OS=Homo sapiens OX=9606 GN=UQCRB PE=1 SV=2 6.07 2237.7 - 630627 - - - -2.0145 - 1.671 0.293 - 181.6 1 2 0 -0.0026 10 0 0 0 1.05E+07 8.88E+06 - - - 3.3054 0.9997 221125_WJC_METTL3_EV_vs_WT_F05.11091.11091.3 0.119 13/40 R.K[136.11]EEELQAALAR[166.11].A "sp|Q7Z406|MYH14_HUMAN,sp|P35749|MYH11_HUMAN,sp|P35579|MYH9_HUMAN,tr|A0A0C4DFM8|A0A0C4DFM8_HUMAN" 4 1274.6949 1.11 63341 11091 3 1274.694573 425.9056 Myosin-14 OS=Homo sapiens OX=9606 GN=MYH14 PE=1 SV=2 4.79 2238.5 - 6.79E+06 - - - -0.284 - 2.305 0.286 - 432.8 1 2 0 -0.0004 11 0 0 0 9.12E+07 8.25E+07 - - - 4.1008 0.9999 221125_WJC_METTL3_EV_vs_WT_F05.11095.11095.2 3.33E-05 26-Dec K.LSAASGYSDVTDSK[136.11].A sp|Q13670|PM2PB_HUMAN 1 1407.6609 1.27 63345 11095 2 1407.659824 704.8377 Putative postmeiotic segregation increased 2-like protein 11 OS=Homo sapiens OX=9606 GN=PMS2P11 PE=5 SV=1 4.21 2239 - 392316 - - - -0.7672 - 2.425 0.55 - 458.6 1 2 0 -0.0011 14 0 0 0 4.70E+06 3.71E+06 - - - 5.3259 0.9987 221125_WJC_METTL3_EV_vs_WT_F05.11104.11104.3 0.0017 Nov-40 K.K[136.11]TGC[160.03]NVLLIQK[136.11].S sp|P50991|TCPD_HUMAN 1 1288.7508 0.33 63352 11104 3 1288.74989 430.5909 T-complex protein 1 subunit delta OS=Homo sapiens OX=9606 GN=CCT4 PE=1 SV=4 9.31 2240.1 - 991173 - - - -0.7007 - 1.601 0.293 - 201 1 2 0 -0.0009 11 0 0 0 9.10E+06 2.79E+07 - - - 3.1434 0.9999 221125_WJC_METTL3_EV_vs_WT_F05.11105.11105.2 2.24E-07 14/22 K.APSSLSDAVPQR[166.11].A "sp|Q8IX01|SUGP2_HUMAN,tr|M0R2Z9|M0R2Z9_HUMAN,tr|M0R3F6|M0R3F6_HUMAN" 3 1236.6338 0.32 63353 11105 2 1236.633303 619.3242 SURP and G-patch domain-containing protein 2 OS=Homo sapiens OX=9606 GN=SUGP2 PE=1 SV=2 5.88 2240.2 - 945542 - - - -0.3898 - 2.621 0.481 - 794.8 1 2 0 -0.0005 12 0 0 0 1.74E+07 5.39E+07 - - - 5.1288 0.9917 221125_WJC_METTL3_EV_vs_WT_F05.11108.11108.2 0.00283 20-Sep K.QDLPALEEK[136.11]PR[166.11].N "sp|P34932|HSP74_HUMAN,tr|A0A087WTS8|A0A087WTS8_HUMAN,tr|A0A087WYC1|A0A087WYC1_HUMAN" 3 1312.7106 0.01 63356 11108 2 1312.703493 657.3626 Heat shock 70 kDa protein 4 OS=Homo sapiens OX=9606 GN=HSPA4 PE=1 SV=4 4.68 2240.6 - 468678 - - - -5.4026 - 1.857 0.375 - 225.1 1 2 0 -0.0071 11 0 0 0 1.44E+05 1.28E+07 - - - 3.483 0.9991 221125_WJC_METTL3_EV_vs_WT_F05.11112.11112.2 0.0214 24-Aug K.LNQPPEDGISSVK.F "sp|O43684|BUB3_HUMAN,tr|J3QT28|J3QT28_HUMAN,tr|J3QSX4|J3QSX4_HUMAN" 3 1382.7042 0.4 63360 11112 2 1382.705096 692.3594 Mitotic checkpoint protein BUB3 OS=Homo sapiens OX=9606 GN=BUB3 PE=1 SV=1 4.37 2241.1 - 246963 - - - 0.6777 - 1.647 0.303 - 188.6 1 2 0 0.0009 13 0 0 0 6.82E+06 1.70E+07 - - - 2.5592 0.9999 221125_WJC_METTL3_EV_vs_WT_F05.11113.11113.2 8.78E-05 24-Dec R.DIQENDEEAVQVK.E "sp|O00231|PSD11_HUMAN,tr|J3QRY4|J3QRY4_HUMAN" 2 1515.7053 0.75 63361 11113 2 1515.704212 758.8599 26S proteasome non-ATPase regulatory subunit 11 OS=Homo sapiens OX=9606 GN=PSMD11 PE=1 SV=3 3.83 2241.2 - 162463 - - - -0.7059 - 2.314 0.558 - 388 1 2 0 -0.0011 13 0 0 0 2.22E+07 2.94E+07 - - - 5.3153 0.9988 221125_WJC_METTL3_EV_vs_WT_F05.11118.11118.3 0.00736 13/40 K.LQQLVENIDKK.A "sp|Q9NSC2|SALL1_HUMAN,sp|Q9BXA9|SALL3_HUMAN,tr|A0A087WXW6|A0A087WXW6_HUMAN,tr|A0A140TA74|A0A140TA74_HUMAN,tr|A0A140TA70|A0A140TA70_HUMAN,tr|H3BSM9|H3BSM9_HUMAN,tr|A9JR48|A9JR48_HUMAN" 7 1326.7507 4.29 63364 11118 3 1326.74775 443.2575 Sal-like protein 1 OS=Homo sapiens OX=9606 GN=SALL1 PE=1 SV=2 6.07 2241.7 - 1.99E+06 - - - -2.2355 - 1.962 0.296 - 302.3 1 2 0 -0.003 11 0 0 0 2.60E+07 6.06E+06 - - - 3.7539 0.9971 221125_WJC_METTL3_EV_vs_WT_F05.11126.11126.3 0.00313 Dec-36 K.VYINLDK[136.11]ETK[136.11].T sp|O75380|NDUS6_HUMAN 1 1237.6889 1.77 63372 11126 3 1237.686904 413.5702 "NADH dehydrogenase [ubiquinone] iron-sulfur protein 6, mitochondrial OS=Homo sapiens OX=9606 GN=NDUFS6 PE=1 SV=1" 6.04 2242.4 - 878950 - - - -1.6159 - 1.984 0.302 - 148.7 1 2 1 -0.002 10 0 0 0 2.26E+07 1.28E+07 - - - 3.9073 0.9998 221125_WJC_METTL3_EV_vs_WT_F05.11127.11127.2 1.02E-06 24-Dec K.NLSSDEATNPISR.V sp|Q7Z417|NUFP2_HUMAN 1 1402.6688 2.12 63373 11127 2 1402.671355 702.3417 Nuclear fragile X mental retardation-interacting protein 2 OS=Homo sapiens OX=9606 GN=NUFIP2 PE=1 SV=1 4.37 2242.6 - 812568 - - - 1.7959 - 2.645 0.539 - 432.6 1 2 0 0.0025 13 0 0 0 3.15E+07 1.48E+07 - - - 5.5177 0.9989 221125_WJC_METTL3_EV_vs_WT_F05.11132.11132.2 2.63E-05 13/26 K.IQALQQQADEAEDR[166.11].A "sp|P67936|TPM4_HUMAN,tr|A0A590UJB9|A0A590UJB9_HUMAN,tr|A0A2R8Y5V9|A0A2R8Y5V9_HUMAN,tr|A0A2R8YGX3|A0A2R8YGX3_HUMAN,tr|A0A590UK79|A0A590UK79_HUMAN" 5 1623.7728 1.54 63378 11132 2 1623.766189 812.8937 Tropomyosin alpha-4 chain OS=Homo sapiens OX=9606 GN=TPM4 PE=1 SV=3 3.92 2243.2 - 248792 - - - -4.0702 - 2.529 0.493 - 410.5 1 2 0 -0.0066 14 0 0 0 4.47E+06 2.90E+06 - - - 5.0086 0.9969 221125_WJC_METTL3_EV_vs_WT_F05.11135.11135.2 0.000409 24-Dec R.DIQENDEEAVQVK[136.11].E "sp|O00231|PSD11_HUMAN,tr|J3QRY4|J3QRY4_HUMAN" 2 1523.7195 0.75 63379 11135 2 1523.711846 762.867 26S proteasome non-ATPase regulatory subunit 11 OS=Homo sapiens OX=9606 GN=PSMD11 PE=1 SV=3 3.83 2243.6 - 1.91E+06 - - - -5.0114 - 2.115 0.468 - 282.1 1 2 0 -0.0076 13 0 0 0 2.22E+07 2.94E+07 - - - 4.4177 0.9979 221125_WJC_METTL3_EV_vs_WT_F05.11139.11139.3 8.12E-08 14/40 L.SMMDVDHQIAK[136.11].L "sp|P48643|TCPE_HUMAN,tr|E9PCA1|E9PCA1_HUMAN,tr|B7ZAR1|B7ZAR1_HUMAN" 3 1281.5937 1.12 63383 11139 3 1281.592318 428.2052 T-complex protein 1 subunit epsilon OS=Homo sapiens OX=9606 GN=CCT5 PE=1 SV=1 5.19 2244 - 727609 - - - -1.0729 - 2.344 0.551 - 205.6 1 1 0 -0.0014 11 0 0 0 1.28E+07 1.14E+07 - - - 7.1027 0.9996 221125_WJC_METTL3_EV_vs_WT_F05.11141.11141.2 0.000171 22-Sep K.GSFSDTGLGDGK[136.11].M "sp|Q9Y2W1|TR150_HUMAN,tr|A0A3B3ITZ9|A0A3B3ITZ9_HUMAN" 2 1147.5237 2.62 63384 11141 2 1147.520988 574.7691 Thyroid hormone receptor-associated protein 3 OS=Homo sapiens OX=9606 GN=THRAP3 PE=1 SV=2 4.21 2244.3 - 2.75E+08 - - - -2.3477 - 1.925 0.529 - 151.1 1 2 0 -0.0027 12 0 0 0 1.16E+10 4.45E+09 - - - 4.6706 1 221125_WJC_METTL3_EV_vs_WT_F05.11145.11145.2 1.15E-06 13/24 K.NLSSDEATNPISR[166.11].V sp|Q7Z417|NUFP2_HUMAN 1 1412.6771 2.06 63387 11145 2 1412.675494 707.3458 Nuclear fragile X mental retardation-interacting protein 2 OS=Homo sapiens OX=9606 GN=NUFIP2 PE=1 SV=1 4.37 2244.7 - 932358 - - - -1.1411 - 2.742 0.624 - 498.6 1 2 0 -0.0016 13 0 0 0 3.05E+07 1.48E+07 - - - 6.2382 0.9806 221125_WJC_METTL3_EV_vs_WT_F05.11146.11146.3 0.0238 Nov-48 R.ALDK[136.11]LDGTEINGR[166.11].N "sp|Q13247|SRSF6_HUMAN,tr|A0A590UK80|A0A590UK80_HUMAN,tr|A0A590UJK4|A0A590UJK4_HUMAN,tr|A0A590UJP7|A0A590UJP7_HUMAN,tr|A0A590UK01|A0A590UK01_HUMAN" 5 1418.7484 1.15 63388 11146 3 1418.744219 473.9234 Serine\arginine-rich splicing factor 6 OS=Homo sapiens OX=9606 GN=SRSF6 PE=1 SV=2 4.56 2244.8 - 820858 - - - -2.966 - 1.993 0.25 - 175 1 2 1 -0.0042 13 0 0 0 4.64E+07 4.03E+07 - - - 3.1959 0.9177 221125_WJC_METTL3_EV_vs_WT_F05.11148.11148.3 0.0348 Oct-36 M.PQNEYIELHR.K "sp|O95478|NSA2_HUMAN,tr|A0A0A0MQZ6|A0A0A0MQZ6_HUMAN" 2 1297.6415 3.13 63390 11148 3 1297.649348 433.5544 Ribosome biogenesis protein NSA2 homolog OS=Homo sapiens OX=9606 GN=NSA2 PE=1 SV=1 5.41 2245.1 - 1.18E+06 - - - 6.0487 - 1.72 0.226 - 182.6 1 2 0 0.0078 10 0 0 0 9.08E+06 2.90E+06 - - - 2.6413 0.9888 221125_WJC_METTL3_EV_vs_WT_F05.11154.11154.2 0.0511 12-Oct R.HLQLAIR.N "sp|P16104|H2AX_HUMAN,sp|Q9BTM1|H2AJ_HUMAN,sp|Q93077|H2A1C_HUMAN,sp|Q99878|H2A1J_HUMAN,sp|Q16777|H2A2C_HUMAN,sp|Q96QV6|H2A1A_HUMAN,sp|P0C0S5|H2AZ_HUMAN,sp|P04908|H2A1B_HUMAN,sp|P20671|H2A1D_HUMAN,sp|P0C0S8|H2A1_HUMAN,sp|Q6FI13|H2A2A_HUMAN,sp|Q96KK5|H2A1H_HUMAN,sp|Q71UI9|H2AV_HUMAN,sp|Q7L7L0|H2A3_HUMAN,tr|C9J386|C9J386_HUMAN,tr|A0A0U1RR32|A0A0U1RR32_HUMAN,tr|A0A0U1RRH7|A0A0U1RRH7_HUMAN,tr|A0A3B3IS11|A0A3B3IS11_HUMAN,tr|H0YFX9|H0YFX9_HUMAN,tr|C9J0D1|C9J0D1_HUMAN,tr|A0A494C189|A0A494C189_HUMAN" 21 849.5185 1.19 63394 11154 2 849.516598 425.7665 Histone H2AX OS=Homo sapiens OX=9606 GN=H2AX PE=1 SV=2 9.76 2245.7 - 6.41E+06 - - - -2.2048 - 1.632 0.079 - 376.2 1 2 0 -0.0019 7 0 0 0 8.00E+07 6.73E+07 - - - 1.1759 0.9907 221125_WJC_METTL3_EV_vs_WT_F05.11155.11155.3 0.00132 Dec-40 R.C[160.03]K[136.11]DGVVFGVEK[136.11].L sp|P25788|PSA3_HUMAN 1 1252.6457 0.85 63395 11155 3 1252.64077 418.5558 Proteasome subunit alpha type-3 OS=Homo sapiens OX=9606 GN=PSMA3 PE=1 SV=2 6.06 2245.8 - 1.33E+06 - - - -3.9029 - 2.056 0.331 - 190.4 1 2 1 -0.0049 11 0 0 0 2.04E+07 2.41E+07 - - - 4.2765 1 221125_WJC_METTL3_EV_vs_WT_F05.11162.11162.2 3.12E-06 15/26 K.AQAELVGTADEATR.A sp|P30049|ATPD_HUMAN 1 1430.7001 1.81 63400 11162 2 1430.700666 716.3573 "ATP synthase subunit delta, mitochondrial OS=Homo sapiens OX=9606 GN=ATP5F1D PE=1 SV=2" 4.14 2246.6 - 4.45E+06 - - - 0.3697 - 3.225 0.631 - 747.8 1 2 0 0.0005 14 0 0 0 1.07E+08 5.95E+07 - - - 6.6398 1 221125_WJC_METTL3_EV_vs_WT_F05.11163.11163.2 0.00021 14/26 K.AQAELVGTADEATR[166.11].A sp|P30049|ATPD_HUMAN 1 1440.7084 1.85 63401 11163 2 1440.702876 721.3615 "ATP synthase subunit delta, mitochondrial OS=Homo sapiens OX=9606 GN=ATP5F1D PE=1 SV=2" 4.14 2246.7 - 2.45E+06 - - - -3.8391 - 3.024 0.541 - 644 1 2 0 -0.0055 14 0 0 0 1.10E+08 5.96E+07 - - - 5.812 0.9996 221125_WJC_METTL3_EV_vs_WT_F05.11164.11164.3 0.00028 Dec-48 R.ALDKLDGTEINGR.N "sp|Q13247|SRSF6_HUMAN,tr|A0A590UK80|A0A590UK80_HUMAN,tr|A0A590UJK4|A0A590UJK4_HUMAN,tr|A0A590UJP7|A0A590UJP7_HUMAN,tr|A0A590UK01|A0A590UK01_HUMAN" 5 1400.726 1.15 63402 11164 3 1400.723499 467.9159 Serine\arginine-rich splicing factor 6 OS=Homo sapiens OX=9606 GN=SRSF6 PE=1 SV=2 4.56 2246.8 - 1.73E+06 - - - -1.7548 - 2.398 0.429 - 186.6 1 2 1 -0.0025 13 0 0 0 4.65E+07 4.03E+07 - - - 5.6936 0.9923 221125_WJC_METTL3_EV_vs_WT_F05.11165.11165.3 0.00897 17/44 M.AIEHADFAGVER[166.11].L "sp|P78371|TCPB_HUMAN,tr|F8VQ14|F8VQ14_HUMAN,tr|F5GWF6|F5GWF6_HUMAN" 3 1323.6447 0.4 63403 11165 3 1323.642678 442.2222 T-complex protein 1 subunit beta OS=Homo sapiens OX=9606 GN=CCT2 PE=1 SV=4 4.65 2246.8 - 1.32E+06 - - - -1.5155 - 2.536 0.418 - 576.4 1 1 0 -0.002 12 0 0 0 1.52E+07 3.78E+07 - - - 5.7792 0.9978 221125_WJC_METTL3_EV_vs_WT_F05.11166.11166.3 0.0107 Dec-52 K.AQAELVGTADEATR[166.11].A sp|P30049|ATPD_HUMAN 1 1440.7084 1.86 63404 11166 3 1440.706067 481.2434 "ATP synthase subunit delta, mitochondrial OS=Homo sapiens OX=9606 GN=ATP5F1D PE=1 SV=2" 4.14 2246.9 - 802900 - - - -1.6242 - 1.85 0.254 - 181.5 1 2 0 -0.0023 14 0 0 0 2.65E+07 1.42E+07 - - - 3.0061 0.9996 221125_WJC_METTL3_EV_vs_WT_F05.11171.11171.3 0.000333 Dec-52 K.AQAELVGTADEATR.A sp|P30049|ATPD_HUMAN 1 1430.7001 1.82 63407 11171 3 1430.695626 477.9073 "ATP synthase subunit delta, mitochondrial OS=Homo sapiens OX=9606 GN=ATP5F1D PE=1 SV=2" 4.14 2247.6 - 1.58E+06 - - - -3.153 - 2.412 0.392 - 290.6 1 2 0 -0.0045 14 0 0 0 2.65E+07 1.46E+07 - - - 5.249 0.9996 221125_WJC_METTL3_EV_vs_WT_F05.11174.11174.2 7.09E-06 20-Nov K.EQVANSAFVER.V "sp|P08238|HS90B_HUMAN,sp|Q58FF7|H90B3_HUMAN" 2 1248.6099 0.66 63410 11174 2 1248.606633 625.3122 Heat shock protein HSP 90-beta OS=Homo sapiens OX=9606 GN=HSP90AB1 PE=1 SV=4 4.53 2247.9 - 518926 - - - -2.5885 - 2.235 0.498 - 521.4 1 2 0 -0.0032 11 0 0 0 9.68E+06 1.47E+07 - - - 4.8939 0.9999 221125_WJC_METTL3_EV_vs_WT_F05.11178.11178.3 7.30E-06 17/48 K.NPLPPSVGVVDK[136.11]K[136.11].E sp|Q8NC51|PAIRB_HUMAN 1 1364.7999 0.79 63413 11178 3 1364.794794 455.9406 Plasminogen activator inhibitor 1 RNA-binding protein OS=Homo sapiens OX=9606 GN=SERBP1 PE=1 SV=2 8.59 2248.4 - 916503 - - - -3.7053 - 2.888 0.517 - 413.5 1 2 0 -0.0051 13 0 0 0 1.37E+07 1.73E+07 - - - 7.1781 0.9999 221125_WJC_METTL3_EV_vs_WT_F05.11180.11180.2 8.23E-05 14/16 R.HLALNLQEK[136.11].S "sp|Q14683|SMC1A_HUMAN,tr|G8JLG1|G8JLG1_HUMAN,tr|A0A6Q8PHC3|A0A6Q8PHC3_HUMAN" 3 1072.612 0.98 63414 11180 2 1072.610744 537.3133 Structural maintenance of chromosomes protein 1A OS=Homo sapiens OX=9606 GN=SMC1A PE=1 SV=2 6.75 2248.6 - 1.97E+06 - - - -1.212 - 2.499 0.511 - 627 1 2 0 -0.0013 9 0 0 0 5.90E+07 6.05E+07 - - - 5.4646 0.9997 221125_WJC_METTL3_EV_vs_WT_F05.11181.11181.2 2.72E-05 15/16 R.HLALNLQEK.S "sp|Q14683|SMC1A_HUMAN,tr|G8JLG1|G8JLG1_HUMAN,tr|A0A6Q8PHC3|A0A6Q8PHC3_HUMAN" 3 1064.5978 0.98 63415 11181 2 1064.599851 533.3062 Structural maintenance of chromosomes protein 1A OS=Homo sapiens OX=9606 GN=SMC1A PE=1 SV=2 6.75 2248.8 - 2.06E+06 - - - 1.8852 - 2.655 0.381 - 831.6 1 2 0 0.002 9 0 0 0 5.90E+07 6.04E+07 - - - 4.6793 0.9985 221125_WJC_METTL3_EV_vs_WT_F05.11186.11186.2 0.00541 16-Oct R.LENEIQTYR.S "sp|P13645|K1C10_HUMAN,tr|A0A1B0GVI3|A0A1B0GVI3_HUMAN" 2 1164.5775 22.94 63418 11186 2 1164.573959 583.296 "Keratin, type I cytoskeletal 10 OS=Homo sapiens OX=9606 GN=KRT10 PE=1 SV=6" 4.53 2249.4 - 4.21E+06 - - - -3.0423 - 1.976 0.336 - 340.5 1 2 0 -0.0035 9 0 0 0 3.39E+07 1.48E+06 - - - 3.492 1 221125_WJC_METTL3_EV_vs_WT_F05.11188.11188.2 2.12E-07 16/26 R.LSDGEINAQESTYK.V "sp|Q2KHR3|QSER1_HUMAN,tr|A0A3B3IRW6|A0A3B3IRW6_HUMAN" 2 1553.7209 2.42 63420 11188 2 1553.724642 777.8677 Glutamine and serine-rich protein 1 OS=Homo sapiens OX=9606 GN=QSER1 PE=1 SV=3 4.14 2249.7 - 892402 - - - 2.3878 - 2.816 0.578 - 502.7 1 2 0 0.0037 14 0 0 0 1.28E+07 5.28E+06 - - - 5.907 0.9988 221125_WJC_METTL3_EV_vs_WT_F05.11191.11191.2 0.00774 16-Sep K.SQSAEDYLK[136.11].S "sp|Q6ZU65|UBN2_HUMAN,tr|H7C4P8|H7C4P8_HUMAN" 2 1047.4964 1.34 63423 11191 2 1047.494812 524.7555 Ubinuclein-2 OS=Homo sapiens OX=9606 GN=UBN2 PE=1 SV=2 4.37 2250.1 - 578568 - - - -1.5208 - 1.74 0.27 - 282.5 1 2 0 -0.0016 9 0 0 0 1.24E+07 9.27E+06 - - - 2.6371 0.8634 221125_WJC_METTL3_EV_vs_WT_F05.11192.11192.3 0.0168 Aug-44 R.IYSYVVSRPQPR.G sp|Q96CS3|FAF2_HUMAN 1 1463.7885 1.7 63424 11192 3 1463.791957 488.9368 FAS-associated factor 2 OS=Homo sapiens OX=9606 GN=FAF2 PE=1 SV=2 9.99 2250.2 - 501963 - - - 2.363 - 1.627 0.077 - 60 1 2 0 0.0035 12 0 0 0 7.60E+06 4.47E+06 - - - 0.7467 0.9994 221125_WJC_METTL3_EV_vs_WT_F05.11194.11194.2 0.00169 20-Sep R.VVWNSSTVQQK[136.11].E "tr|A0A087WVZ6|A0A087WVZ6_HUMAN,tr|H7C4X9|H7C4X9_HUMAN" 2 1282.6761 0.32 63426 11194 2 1282.676771 642.3453 Protein kinase C-binding protein 1 OS=Homo sapiens OX=9606 GN=ZMYND8 PE=1 SV=2 8.72 2250.4 - 275174 - - - 0.5231 - 1.628 0.341 - 201.5 1 2 0 0.0007 11 0 0 0 1.09E+06 3.43E+06 - - - 2.8778 0.9999 221125_WJC_METTL3_EV_vs_WT_F05.11198.11198.2 1.13E-06 26-Dec R.SSFYPDGGDQETAK.T "sp|Q9NYF8|BCLF1_HUMAN,tr|H0YF00|H0YF00_HUMAN,tr|E9PKI6|E9PKI6_HUMAN,tr|A0A1W2PQ43|A0A1W2PQ43_HUMAN,tr|E9PK91|E9PK91_HUMAN,tr|E9PJA7|E9PJA7_HUMAN,tr|E9PK09|E9PK09_HUMAN,tr|E9PQN2|E9PQN2_HUMAN" 8 1500.6369 2.32 63428 11198 2 1500.635887 751.3257 Bcl-2-associated transcription factor 1 OS=Homo sapiens OX=9606 GN=BCLAF1 PE=1 SV=2 4.03 2250.9 - 2.33E+06 - - - -0.6537 - 1.808 0.612 - 271.8 1 2 0 -0.001 14 0 0 0 3.10E+08 1.33E+08 - - - 5.0471 1 221125_WJC_METTL3_EV_vs_WT_F05.11199.11199.2 9.05E-08 16/28 K.GGGGGGPGEGFDVAK[136.11].T sp|Q9Y295|DRG1_HUMAN 1 1268.5877 0.54 63429 11199 2 1268.584428 635.3011 Developmentally-regulated GTP-binding protein 1 OS=Homo sapiens OX=9606 GN=DRG1 PE=1 SV=1 4.37 2251 - 1.27E+06 - - - -2.5627 - 3.04 0.614 - 1164.3 1 2 0 -0.0033 15 0 0 0 2.25E+07 4.19E+07 - - - 6.3085 0.9996 221125_WJC_METTL3_EV_vs_WT_F05.11201.11201.2 0.000985 16-Sep K.SQSAEDYLK.S "sp|Q6ZU65|UBN2_HUMAN,tr|H7C4P8|H7C4P8_HUMAN" 2 1039.4822 1.34 63431 11201 2 1039.481847 520.7484 Ubinuclein-2 OS=Homo sapiens OX=9606 GN=UBN2 PE=1 SV=2 4.37 2251.2 - 988294 - - - -0.3444 - 1.679 0.384 - 294.1 1 2 0 -0.0004 9 0 0 0 1.24E+07 9.27E+06 - - - 3.3763 0.9996 221125_WJC_METTL3_EV_vs_WT_F05.11203.11203.2 0.00117 20-Oct K.EQVANSAFVER[166.11].V "sp|P08238|HS90B_HUMAN,sp|Q58FF7|H90B3_HUMAN" 2 1258.6181 0.67 63433 11203 2 1258.617501 630.3163 Heat shock protein HSP 90-beta OS=Homo sapiens OX=9606 GN=HSP90AB1 PE=1 SV=4 4.53 2251.5 - 793975 - - - -0.5037 - 1.978 0.326 - 450.8 1 2 0 -0.0006 11 0 0 0 1.06E+07 1.59E+07 - - - 3.2938 1 221125_WJC_METTL3_EV_vs_WT_F05.11206.11206.2 4.36E-09 14/26 R.LSDGEINAQESTYK[136.11].V "sp|Q2KHR3|QSER1_HUMAN,tr|A0A3B3IRW6|A0A3B3IRW6_HUMAN" 2 1561.7351 2.42 63436 11206 2 1561.731784 781.8748 Glutamine and serine-rich protein 1 OS=Homo sapiens OX=9606 GN=QSER1 PE=1 SV=3 4.14 2251.9 - 502987 - - - -2.1438 - 3.084 0.625 - 817.8 1 2 0 -0.0033 14 0 0 0 1.28E+07 5.28E+06 - - - 6.4824 1 221125_WJC_METTL3_EV_vs_WT_F05.11210.11210.3 1.86E-06 Nov-44 R.K[136.11]FGDPVVQSDMK[136.11].H "sp|P0DMV8|HS71A_HUMAN,sp|P0DMV9|HS71B_HUMAN,tr|A0A0G2JIW1|A0A0G2JIW1_HUMAN" 3 1365.6933 0.12 63438 11210 3 1365.692188 456.2384 Heat shock 70 kDa protein 1A OS=Homo sapiens OX=9606 GN=HSPA1A PE=1 SV=1 5.96 2252.4 - 5.79E+06 - - - -0.8413 - 2.579 0.529 - 303.5 1 2 0 -0.0011 12 0 0 0 2.41E+08 2.09E+09 - - - 7.0636 0.8821 221125_WJC_METTL3_EV_vs_WT_F05.11212.11212.3 0.00231 Nov-40 K.QR[166.11]YPDGIISK[136.11]P.K sp|Q86U44|MTA70_HUMAN 1 1290.7051 0.04 63440 11212 3 1290.704408 431.2423 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 8.59 2252.5 - 1.41E+06 - - - -0.5408 - 1.733 0.376 - 131 1 1 1 -0.0007 11 0 0 0 4.72E+06 1.12E+08 - - - 4.2939 0.9999 221125_WJC_METTL3_EV_vs_WT_F05.11213.11213.2 3.95E-10 15/28 K.GGGGGGPGEGFDVAK.T sp|Q9Y295|DRG1_HUMAN 1 1260.5735 0.54 63441 11213 2 1260.571487 631.294 Developmentally-regulated GTP-binding protein 1 OS=Homo sapiens OX=9606 GN=DRG1 PE=1 SV=1 4.37 2252.6 - 879024 - - - -1.5802 - 2.878 0.512 - 927.7 1 2 0 -0.002 15 0 0 0 2.25E+07 4.18E+07 - - - 5.4209 0.9993 221125_WJC_METTL3_EV_vs_WT_F05.11216.11216.2 0.000498 20-Jul K.NSEPEEVIPSR.L "sp|P54577|SYYC_HUMAN,tr|A0A6Q8PFX2|A0A6Q8PFX2_HUMAN" 2 1255.6044 0.51 63444 11216 2 1255.605756 628.8095 "Tyrosine--tRNA ligase, cytoplasmic OS=Homo sapiens OX=9606 GN=YARS1 PE=1 SV=4" 4.25 2253 - 400150 - - - 1.0441 - 1.623 0.365 - 174.3 1 2 0 0.0013 11 0 0 0 1.42E+07 2.81E+07 - - - 3.0466 0.9991 221125_WJC_METTL3_EV_vs_WT_F05.11217.11217.3 0.000554 Sep-44 R.GIVEESVTGVHR.L "sp|O43865|SAHH2_HUMAN,sp|Q96HN2|SAHH3_HUMAN,tr|H0Y8B3|H0Y8B3_HUMAN" 3 1281.6677 0.83 63445 11217 3 1281.663978 428.2298 S-adenosylhomocysteine hydrolase-like protein 1 OS=Homo sapiens OX=9606 GN=AHCYL1 PE=1 SV=2 5.4 2253.1 - 322449 - - - -2.915 - 1.95 0.352 - 109.4 1 2 0 -0.0037 12 0 0 0 1.13E+07 1.36E+07 - - - 4.3145 1 221125_WJC_METTL3_EV_vs_WT_F05.11220.11220.2 4.29E-10 15/30 K.APVPGTPDSLSSGSSR.D "sp|Q9UJZ1|STML2_HUMAN,tr|A0A087WYB4|A0A087WYB4_HUMAN" 2 1513.7372 2.22 63446 11220 2 1513.732683 757.8759 "Stomatin-like protein 2, mitochondrial OS=Homo sapiens OX=9606 GN=STOML2 PE=1 SV=1" 5.88 2253.5 - 980211 - - - -3.017 - 2.465 0.646 - 548.9 1 2 0 -0.0046 16 0 0 0 3.28E+07 1.48E+07 - - - 6.029 0.9994 221125_WJC_METTL3_EV_vs_WT_F05.11226.11226.2 2.46E-07 16/28 K.QLSAQSYGVTSSTAR[166.11].R sp|P49790|NU153_HUMAN 1 1564.7721 1.22 63452 11226 2 1564.777397 783.3933 Nuclear pore complex protein Nup153 OS=Homo sapiens OX=9606 GN=NUP153 PE=1 SV=2 8.75 2254.2 - 450486 - - - 3.405 - 2.994 0.491 - 1002.1 1 2 0 0.0053 15 0 0 0 2.37E+07 1.95E+07 - - - 5.3619 0.9999 221125_WJC_METTL3_EV_vs_WT_F05.11227.11227.2 0.000234 18-Nov K.C[160.03]DTC[160.03]QQYFSR[166.11].T sp|Q9Y2X9|ZN281_HUMAN 1 1373.5368 1.1 63453 11227 2 1373.536825 687.7757 Zinc finger protein 281 OS=Homo sapiens OX=9606 GN=ZNF281 PE=1 SV=1 5.82 2254.3 - 414040 - - - 0.0255 - 2.31 0.569 - 337.7 1 2 0 0 10 0 0 0 5.75E+06 5.24E+06 - - - 5.5806 0.9999 221125_WJC_METTL3_EV_vs_WT_F05.11229.11229.2 1.09E-05 20-Sep K.EQYEALQEETR[166.11].V "sp|Q9UPN3|MACF1_HUMAN,tr|H3BQK9|H3BQK9_HUMAN,tr|A0A7P0MQR8|A0A7P0MQR8_HUMAN,tr|E9PNZ4|E9PNZ4_HUMAN,tr|H0Y390|H0Y390_HUMAN,tr|H3BPE1|H3BPE1_HUMAN,tr|A0A590UJG2|A0A590UJG2_HUMAN" 7 1404.6397 2.09 63455 11229 2 1404.639407 703.3271 "Microtubule-actin cross-linking factor 1, isoforms 1\2\3\5 OS=Homo sapiens OX=9606 GN=MACF1 PE=1 SV=4" 4.09 2254.6 - 214393 - - - -0.1787 - 2.07 0.473 - 352.5 1 2 0 -0.0003 11 0 0 0 8.44E+06 4.04E+06 - - - 4.5027 0.9994 221125_WJC_METTL3_EV_vs_WT_F05.11234.11234.3 0.000362 Oct-36 R.LKVEELEGER.S sp|Q9Y6D9|MD1L1_HUMAN 1 1200.635 1.71 63458 11234 3 1200.634275 401.2189 Mitotic spindle assembly checkpoint protein MAD1 OS=Homo sapiens OX=9606 GN=MAD1L1 PE=1 SV=2 4.49 2255.2 - 1.95E+06 - - - -0.618 - 2.106 0.383 - 129.8 1 2 1 -0.0007 10 0 0 0 5.59E+07 3.27E+07 - - - 4.985 0.9999 221125_WJC_METTL3_EV_vs_WT_F05.11235.11235.3 2.83E-06 Dec-56 K.VGAHAGEYGAEALER.M "sp|P69905|HBA_HUMAN,tr|A0A2R8Y7C0|A0A2R8Y7C0_HUMAN" 2 1528.727 2.75 63459 11235 3 1528.724289 510.5829 Hemoglobin subunit alpha OS=Homo sapiens OX=9606 GN=HBA1 PE=1 SV=2 4.75 2255.3 - 848922 - - - -1.7865 - 2.387 0.485 - 113.7 1 2 0 -0.0027 15 0 0 0 7.18E+06 2.61E+06 - - - 6.2168 0.9995 221125_WJC_METTL3_EV_vs_WT_F05.11236.11236.2 2.68E-05 14/28 K.QLSAQSYGVTSSTAR.R sp|P49790|NU153_HUMAN 1 1554.7638 1.22 63460 11236 2 1554.76014 778.3892 Nuclear pore complex protein Nup153 OS=Homo sapiens OX=9606 GN=NUP153 PE=1 SV=2 8.75 2255.4 - 842156 - - - -2.3534 - 2.57 0.388 - 241 1 2 0 -0.0037 15 0 0 0 2.37E+07 1.95E+07 - - - 4.2263 1 221125_WJC_METTL3_EV_vs_WT_F05.11237.11237.2 7.63E-10 15/26 R.SVSEINSDDELSGK.G "sp|P82094|TMF1_HUMAN,tr|F8WF45|F8WF45_HUMAN,tr|A0A2R8Y7M0|A0A2R8Y7M0_HUMAN" 3 1478.6736 1.75 63461 11237 2 1478.673066 740.3441 TATA element modulatory factor OS=Homo sapiens OX=9606 GN=TMF1 PE=1 SV=2 3.92 2255.5 - 835872 - - - -0.3929 - 3.003 0.603 - 482.5 1 2 0 -0.0006 14 0 0 0 9.15E+06 5.23E+06 - - - 6.254 0.9999 221125_WJC_METTL3_EV_vs_WT_F05.11238.11238.2 4.53E-05 20-Dec K.EQYEALQEETR.V "sp|Q9UPN3|MACF1_HUMAN,tr|H3BQK9|H3BQK9_HUMAN,tr|A0A7P0MQR8|A0A7P0MQR8_HUMAN,tr|E9PNZ4|E9PNZ4_HUMAN,tr|H0Y390|H0Y390_HUMAN,tr|H3BPE1|H3BPE1_HUMAN,tr|A0A590UJG2|A0A590UJG2_HUMAN" 7 1394.6314 2.09 63462 11238 2 1394.631692 698.323 "Microtubule-actin cross-linking factor 1, isoforms 1\2\3\5 OS=Homo sapiens OX=9606 GN=MACF1 PE=1 SV=4" 4.09 2255.6 - 739256 - - - 0.218 - 2.16 0.536 - 359 1 2 0 0.0003 11 0 0 0 8.44E+06 4.04E+06 - - - 5.0831 0.9993 221125_WJC_METTL3_EV_vs_WT_F05.11239.11239.2 2.95E-05 22-Nov K.SVQVNGAATELR.K "sp|Q92615|LAR4B_HUMAN,tr|A0A087X183|A0A087X183_HUMAN" 2 1243.6521 1.73 63463 11239 2 1243.648366 622.8333 La-related protein 4B OS=Homo sapiens OX=9606 GN=LARP4B PE=1 SV=3 5.72 2255.7 - 593214 - - - -2.9735 - 2.19 0.448 - 479.3 1 2 0 -0.0037 12 0 0 0 9.45E+06 5.45E+06 - - - 4.4113 0.9998 221125_WJC_METTL3_EV_vs_WT_F05.11241.11241.2 0.0473 22-Oct K.SVQVNGAATELR[166.11].K "sp|Q92615|LAR4B_HUMAN,tr|A0A087X183|A0A087X183_HUMAN" 2 1253.6603 1.73 63465 11241 2 1253.660131 627.8374 La-related protein 4B OS=Homo sapiens OX=9606 GN=LARP4B PE=1 SV=3 5.72 2256 - 503992 - - - -0.1619 - 2.435 0.398 - 333.4 1 2 0 -0.0002 12 0 0 0 9.45E+06 5.45E+06 - - - 4.3222 1 221125_WJC_METTL3_EV_vs_WT_F05.11242.11242.2 1.36E-06 14/26 R.SVSEINSDDELSGK[136.11].G "sp|P82094|TMF1_HUMAN,tr|F8WF45|F8WF45_HUMAN,tr|A0A2R8Y7M0|A0A2R8Y7M0_HUMAN" 3 1486.6878 1.75 63466 11242 2 1486.683493 744.3512 TATA element modulatory factor OS=Homo sapiens OX=9606 GN=TMF1 PE=1 SV=2 3.92 2256.1 - 450467 - - - -2.9287 - 2.598 0.588 - 529.9 1 2 0 -0.0044 14 0 0 0 9.15E+06 5.23E+06 - - - 5.7785 0.9642 221125_WJC_METTL3_EV_vs_WT_F05.11244.11244.2 0.00661 24-Oct K.SAGLEQPTDPVAR.D "sp|O75410|TACC1_HUMAN,tr|E7EVI4|E7EVI4_HUMAN,tr|E5RFM9|E5RFM9_HUMAN,tr|R4GMT7|R4GMT7_HUMAN,tr|H0YAY0|H0YAY0_HUMAN,tr|E7ET87|E7ET87_HUMAN" 6 1339.6732 6.62 63468 11244 2 1339.665165 670.8439 Transforming acidic coiled-coil-containing protein 1 OS=Homo sapiens OX=9606 GN=TACC1 PE=1 SV=2 4.37 2256.4 - 416452 - - - -5.9925 - 1.641 0.284 - 68.1 1 2 0 -0.008 13 0 0 0 4.66E+06 7.05E+05 - - - 2.4073 0.998 221125_WJC_METTL3_EV_vs_WT_F05.11245.11245.2 1.25 18-Oct R.LKVEELEGER.S sp|Q9Y6D9|MD1L1_HUMAN 1 1200.635 1.52 63469 11245 2 1200.634391 601.3248 Mitotic spindle assembly checkpoint protein MAD1 OS=Homo sapiens OX=9606 GN=MAD1L1 PE=1 SV=2 4.49 2256.5 - 340979 - - - -0.5214 - 2.264 0.399 - 275.4 1 2 1 -0.0006 10 0 0 0 1.25E+07 8.25E+06 - - - 4.2687 0.9999 221125_WJC_METTL3_EV_vs_WT_F05.11250.11250.2 3.61E-06 26-Dec R.SSFYPDGGDQETAK[136.11].T "sp|Q9NYF8|BCLF1_HUMAN,tr|H0YF00|H0YF00_HUMAN,tr|E9PKI6|E9PKI6_HUMAN,tr|A0A1W2PQ43|A0A1W2PQ43_HUMAN,tr|E9PK91|E9PK91_HUMAN,tr|E9PJA7|E9PJA7_HUMAN,tr|E9PK09|E9PK09_HUMAN,tr|E9PQN2|E9PQN2_HUMAN" 8 1508.6511 2.32 63472 11250 2 1508.650523 755.3328 Bcl-2-associated transcription factor 1 OS=Homo sapiens OX=9606 GN=BCLAF1 PE=1 SV=2 4.03 2257.2 - 8.94E+06 - - - -0.3612 - 1.731 0.588 - 269.2 1 2 0 -0.0005 14 0 0 0 3.09E+08 1.33E+08 - - - 4.7607 1 221125_WJC_METTL3_EV_vs_WT_F05.11251.11251.2 7.51E-06 16/22 R.KFGDPVVQSDMK.H "sp|P0DMV8|HS71A_HUMAN,sp|P0DMV9|HS71B_HUMAN,tr|A0A0G2JIW1|A0A0G2JIW1_HUMAN" 3 1349.6649 0.13 63473 11251 2 1349.666311 675.8397 Heat shock 70 kDa protein 1A OS=Homo sapiens OX=9606 GN=HSPA1A PE=1 SV=1 5.96 2257.3 - 1.80E+06 - - - 1.018 - 2.895 0.551 - 771.2 1 2 0 0.0014 12 0 0 0 5.11E+07 4.02E+08 - - - 5.9071 0.9999 221125_WJC_METTL3_EV_vs_WT_F05.11254.11254.2 4.83E-06 18-Nov R.DGSNVIVTER.V sp|Q02413|DSG1_HUMAN 1 1088.5462 999 63476 11254 2 1088.546421 545.2804 Desmoglein-1 OS=Homo sapiens OX=9606 GN=DSG1 PE=1 SV=2 4.37 2257.6 - 1.38E+06 - - - 0.2012 - 2.271 0.483 - 517.4 1 2 0 0.0002 10 0 0 0 1.39E+07 0.00E+00 - - - 4.8979 1 221125_WJC_METTL3_EV_vs_WT_F05.11255.11255.2 3.74E-07 15/26 R.ELDDATEANEGLSR.E sp|P35580|MYH10_HUMAN 1 1518.6798 1.04 63477 11255 2 1518.675133 760.3472 Myosin-10 OS=Homo sapiens OX=9606 GN=MYH10 PE=1 SV=3 3.83 2257.7 - 1.29E+06 - - - -3.0698 - 2.682 0.624 - 835.9 1 2 0 -0.0047 14 0 0 0 7.27E+07 6.97E+07 - - - 6.1241 1 221125_WJC_METTL3_EV_vs_WT_F05.11264.11264.3 2.37E-05 Nov-44 R.KFGDPVVQSDMK.H "sp|P0DMV8|HS71A_HUMAN,sp|P0DMV9|HS71B_HUMAN,tr|A0A0G2JIW1|A0A0G2JIW1_HUMAN" 3 1349.6649 0.11 63484 11264 3 1349.664296 450.8956 Heat shock 70 kDa protein 1A OS=Homo sapiens OX=9606 GN=HSPA1A PE=1 SV=1 5.96 2258.8 - 1.34E+07 - - - -0.4749 - 2.173 0.516 - 297.9 1 2 0 -0.0006 12 0 0 0 2.39E+08 2.08E+09 - - - 6.444 0.9998 221125_WJC_METTL3_EV_vs_WT_F05.11265.11265.2 3.95E-06 22-Dec R.NAMGSLASQATK[136.11].D "sp|P55036|PSMD4_HUMAN,tr|H0Y3Y9|H0Y3Y9_HUMAN,tr|H0Y561|H0Y561_HUMAN,tr|Q5VWC4|Q5VWC4_HUMAN" 4 1185.5903 1.17 63485 11265 2 1185.588034 593.8024 26S proteasome non-ATPase regulatory subunit 4 OS=Homo sapiens OX=9606 GN=PSMD4 PE=1 SV=1 8.75 2258.9 - 1.49E+06 - - - -1.9298 - 2.498 0.567 - 500.2 1 2 0 -0.0023 12 0 0 0 4.41E+07 3.77E+07 - - - 5.637 1 221125_WJC_METTL3_EV_vs_WT_F05.11266.11266.2 0.000172 14/26 R.ELDDATEANEGLSR[166.11].E sp|P35580|MYH10_HUMAN 1 1528.6881 1.04 63486 11266 2 1528.68449 765.3513 Myosin-10 OS=Homo sapiens OX=9606 GN=MYH10 PE=1 SV=3 3.83 2258.9 - 3.11E+06 - - - -2.3386 - 2.692 0.625 - 720.9 1 2 0 -0.0036 14 0 0 0 7.25E+07 6.95E+07 - - - 6.1412 0.9986 221125_WJC_METTL3_EV_vs_WT_F05.11267.11267.2 3.34E-05 22-Dec R.NAMGSLASQATK.D "sp|P55036|PSMD4_HUMAN,tr|H0Y3Y9|H0Y3Y9_HUMAN,tr|H0Y561|H0Y561_HUMAN,tr|Q5VWC4|Q5VWC4_HUMAN" 4 1177.5761 1.17 63487 11267 2 1177.571375 589.7953 26S proteasome non-ATPase regulatory subunit 4 OS=Homo sapiens OX=9606 GN=PSMD4 PE=1 SV=1 8.75 2259 - 1.47E+06 - - - -4.0312 - 2.361 0.435 - 505.4 1 2 0 -0.0047 12 0 0 0 4.41E+07 3.77E+07 - - - 4.5128 0.9759 221125_WJC_METTL3_EV_vs_WT_F05.11268.11268.2 0.0387 14-Aug R.AK[136.11]VEFNIR[166.11].K sp|Q8NC51|PAIRB_HUMAN 1 993.5726 0.76 63488 11268 2 993.5714 497.7936 Plasminogen activator inhibitor 1 RNA-binding protein OS=Homo sapiens OX=9606 GN=SERBP1 PE=1 SV=2 8.79 2259.2 - 1.14E+06 - - - -1.243 - 1.736 0.169 - 196.8 1 2 1 -0.0012 8 0 0 0 6.52E+07 8.63E+07 - - - 1.9524 0.9956 221125_WJC_METTL3_EV_vs_WT_F05.11269.11269.2 0.243 12-Aug R.LAADDFR.T "sp|Q04695|K1C17_HUMAN,sp|P13645|K1C10_HUMAN,sp|O76015|KRT38_HUMAN,sp|Q2M2I5|K1C24_HUMAN,sp|Q15323|K1H1_HUMAN,sp|P02533|K1C14_HUMAN,sp|P05783|K1C18_HUMAN,sp|P08727|K1C19_HUMAN,sp|P08779|K1C16_HUMAN,sp|Q7Z3Y7|K1C28_HUMAN,sp|Q14532|K1H2_HUMAN,sp|P19012|K1C15_HUMAN,sp|O76013|KRT36_HUMAN,sp|Q14525|KT33B_HUMAN,sp|Q92764|KRT35_HUMAN,sp|O76014|KRT37_HUMAN,sp|P13646|K1C13_HUMAN,tr|F8VZY9|F8VZY9_HUMAN,tr|K7EPJ9|K7EPJ9_HUMAN,tr|C9JM50|C9JM50_HUMAN,tr|A0A1B0GVI3|A0A1B0GVI3_HUMAN,tr|K7EMD9|K7EMD9_HUMAN,tr|F5GWP8|F5GWP8_HUMAN,tr|K7ERE3|K7ERE3_HUMAN,tr|C4AM86|C4AM86_HUMAN" 25 806.3923 45.95 63489 11269 2 806.389733 404.2034 "Keratin, type I cytoskeletal 17 OS=Homo sapiens OX=9606 GN=KRT17 PE=1 SV=2" 4.21 2259.3 - 1.09E+06 - - - -3.1424 - 1.722 0.232 - 222.3 1 2 0 -0.0025 7 0 0 0 3.34E+07 7.28E+05 - - - 2.4758 0.9998 221125_WJC_METTL3_EV_vs_WT_F05.11271.11271.2 0.0021 20-Dec K.SGVQVFQQSSR.G "sp|Q8IZH2|XRN1_HUMAN,tr|H7C5E4|H7C5E4_HUMAN" 2 1221.6102 1.34 63491 11271 2 1221.60969 611.8124 5'-3' exoribonuclease 1 OS=Homo sapiens OX=9606 GN=XRN1 PE=1 SV=1 9.47 2259.5 - 959551 - - - -0.4167 - 2.293 0.399 - 527.2 1 2 0 -0.0005 11 0 0 0 2.91E+07 2.17E+07 - - - 4.2328 0.999 221125_WJC_METTL3_EV_vs_WT_F05.11272.11272.3 0.00167 Nov-44 R.KGNYILSAGVDK.T "sp|O60907|TBL1X_HUMAN,tr|A0A804HJZ5|A0A804HJZ5_HUMAN,tr|A0A2R8YFW3|A0A2R8YFW3_HUMAN" 3 1263.6823 18.55 63492 11272 3 1263.680009 422.2347 F-box-like\WD repeat-containing protein TBL1X OS=Homo sapiens OX=9606 GN=TBL1X PE=1 SV=3 8.5 2259.6 - 618608 - - - -1.8145 - 2.16 0.269 - 249.6 1 2 0 -0.0023 12 0 0 0 7.15E+07 3.85E+06 - - - 3.6731 0.9999 221125_WJC_METTL3_EV_vs_WT_F05.11275.11275.3 0.000693 15/52 K.ALDGINSGITHAGR.E "sp|Q6UWP8|SBSN_HUMAN,tr|K7ESC4|K7ESC4_HUMAN" 2 1380.711 4.11 63494 11275 3 1380.70827 461.2443 Suprabasin OS=Homo sapiens OX=9606 GN=SBSN PE=1 SV=2 6.79 2259.9 - 2.65E+06 - - - -1.9599 - 2.867 0.42 - 224.7 1 2 0 -0.0027 14 0 0 0 3.75E+07 9.14E+06 - - - 6.0209 1 221125_WJC_METTL3_EV_vs_WT_F05.11276.11276.3 0.000676 17/48 K.AALEAQNALHNMK.V "sp|Q92879|CELF1_HUMAN,tr|G5EA30|G5EA30_HUMAN,tr|E9PSH0|E9PSH0_HUMAN,tr|E9PQK4|E9PQK4_HUMAN,tr|E9PKU1|E9PKU1_HUMAN" 5 1409.7085 1.04 63495 11276 3 1409.705839 470.9101 CUGBP Elav-like family member 1 OS=Homo sapiens OX=9606 GN=CELF1 PE=1 SV=2 6.79 2260 - 1.23E+06 - - - -1.911 - 3.046 0.467 - 483 1 2 0 -0.0027 13 0 0 0 3.73E+07 3.60E+07 - - - 6.7658 1 221125_WJC_METTL3_EV_vs_WT_F05.11277.11277.2 0.00383 15/28 R.SLAEAC[160.03]SEGDVNAVR.K "sp|O75179|ANR17_HUMAN,tr|H0YM23|H0YM23_HUMAN,tr|A0A1W2PQ15|A0A1W2PQ15_HUMAN" 3 1576.7151 2.7 63496 11277 2 1576.712666 789.3648 Ankyrin repeat domain-containing protein 17 OS=Homo sapiens OX=9606 GN=ANKRD17 PE=1 SV=3 4.14 2260.1 - 1.08E+06 - - - -1.5659 - 3.262 0.592 - 917.4 1 2 0 -0.0025 15 0 0 0 1.21E+07 4.47E+06 - - - 6.3196 1 221125_WJC_METTL3_EV_vs_WT_F05.11278.11278.2 2.56E-07 16/32 R.GSGGLGGAC[160.03]GGAGFGSR.S "sp|P48668|K2C6C_HUMAN,sp|P04259|K2C6B_HUMAN,sp|P02538|K2C6A_HUMAN" 3 1423.6263 999 63497 11278 2 1423.621442 712.8204 "Keratin, type II cytoskeletal 6C OS=Homo sapiens OX=9606 GN=KRT6C PE=1 SV=3" 8.25 2260.3 - 590360 - - - -3.3843 - 3.028 0.645 - 596.4 1 2 0 -0.0048 17 0 0 0 4.32E+09 0.00E+00 - - - 6.5273 0.9959 221125_WJC_METTL3_EV_vs_WT_F05.11279.11279.2 0.226 18-Sep K.GGQTIVQLQK[136.11].E "sp|P51513|NOVA1_HUMAN,sp|Q9UNW9|NOVA2_HUMAN,tr|F8VWX1|F8VWX1_HUMAN,tr|F8W659|F8W659_HUMAN,tr|J3KQU3|J3KQU3_HUMAN,tr|F8VYI3|F8VYI3_HUMAN,tr|A0A6Q8PFC2|A0A6Q8PFC2_HUMAN,tr|I3L2B5|I3L2B5_HUMAN" 8 1078.6226 13.35 63498 11279 2 1078.622487 540.3186 RNA-binding protein Nova-1 OS=Homo sapiens OX=9606 GN=NOVA1 PE=1 SV=2 8.75 2260.4 - 403596 - - - -0.1122 - 1.478 0.149 - 226.1 1 2 0 -0.0001 10 0 0 0 3.78E+07 2.83E+06 - - - 1.232 0.9908 221125_WJC_METTL3_EV_vs_WT_F05.11282.11282.2 0.0652 18-Jun R.YPDGIISK[136.11]PK[136.11].N sp|Q86U44|MTA70_HUMAN 1 1132.6463 0.14 63501 11282 2 1132.645439 567.3304 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 8.5 2260.8 - 254194 - - - -0.769 - 1.242 0.185 - 84.1 4 2 0 -0.0009 10 0 0 0 5.18E+05 3.66E+06 - - - 0.7431 1 221125_WJC_METTL3_EV_vs_WT_F05.11284.11284.2 2.33E-07 22-Dec K.GSFSDTGLGDGK.M "sp|Q9Y2W1|TR150_HUMAN,tr|A0A3B3ITZ9|A0A3B3ITZ9_HUMAN" 2 1139.5095 2.5 63502 11284 2 1139.50848 570.762 Thyroid hormone receptor-associated protein 3 OS=Homo sapiens OX=9606 GN=THRAP3 PE=1 SV=2 4.21 2261.1 - 7.77E+06 - - - -0.8793 - 2.277 0.612 - 285.6 1 2 0 -0.001 12 0 0 0 1.67E+08 6.71E+07 - - - 5.726 0.9553 221125_WJC_METTL3_EV_vs_WT_F05.11288.11288.2 0.121 14-Aug R.AKVEFNIR.K sp|Q8NC51|PAIRB_HUMAN 1 975.5502 0.76 63505 11288 2 975.551235 488.7824 Plasminogen activator inhibitor 1 RNA-binding protein OS=Homo sapiens OX=9606 GN=SERBP1 PE=1 SV=2 8.79 2261.5 - 1.79E+06 - - - 1.0968 - 1.454 0.177 - 200.5 1 2 1 0.0011 8 0 0 0 6.52E+07 8.63E+07 - - - 1.4769 0.9948 221125_WJC_METTL3_EV_vs_WT_F05.11292.11292.3 0.267 Jul-52 R.ELDDATEANEGLSR.E sp|P35580|MYH10_HUMAN 1 1518.6798 1.86 63509 11292 3 1518.673622 507.2339 Myosin-10 OS=Homo sapiens OX=9606 GN=MYH10 PE=1 SV=3 3.83 2261.9 - 383641 - - - -4.0647 - 1.636 0.34 - 62.9 1 2 0 -0.0062 14 0 0 0 4.64E+06 2.50E+06 - - - 3.6371 0.9795 221125_WJC_METTL3_EV_vs_WT_F05.11294.11294.3 0.0243 Sep-40 M.GKEQELLEAAR.T "sp|Q92625|ANS1A_HUMAN,tr|A0A3B3ISP1|A0A3B3ISP1_HUMAN,tr|A0A3B3ITU5|A0A3B3ITU5_HUMAN" 3 1242.6568 0.4 63511 11294 3 1242.654363 415.2262 Ankyrin repeat and SAM domain-containing protein 1A OS=Homo sapiens OX=9606 GN=ANKS1A PE=1 SV=4 4.79 2262.2 - 354601 - - - -1.9732 - 1.81 0.219 - 91.2 1 2 1 -0.0025 11 0 0 0 4.58E+06 1.15E+07 - - - 2.6665 1 221125_WJC_METTL3_EV_vs_WT_F05.11295.11295.2 0.00182 15/26 R.SPSGSAFGSQENLR[166.11].W "sp|Q96N67|DOCK7_HUMAN,tr|A0A1B0GWE0|A0A1B0GWE0_HUMAN" 2 1445.6774 0.73 63512 11295 2 1445.671344 723.846 Dedicator of cytokinesis protein 7 OS=Homo sapiens OX=9606 GN=DOCK7 PE=1 SV=4 5.72 2262.3 - 443680 - - - -4.2174 - 3.063 0.544 - 776.7 1 2 0 -0.0061 14 0 0 0 3.36E+06 4.58E+06 - - - 5.8661 0.9999 221125_WJC_METTL3_EV_vs_WT_F05.11298.11298.3 0.224 16/40 K.KLSVPASVVSR.L "sp|Q8IWZ3|ANKH1_HUMAN,tr|A0A0A0MQZ8|A0A0A0MQZ8_HUMAN,tr|H0Y472|H0Y472_HUMAN,tr|H0Y7Y3|H0Y7Y3_HUMAN,tr|H0Y4P6|H0Y4P6_HUMAN,tr|H0Y785|H0Y785_HUMAN" 6 1141.6819 1.28 63513 11298 3 1141.681399 381.5679 Ankyrin repeat and KH domain-containing protein 1 OS=Homo sapiens OX=9606 GN=ANKHD1 PE=1 SV=1 11 2262.7 - 2.08E+06 - - - -0.4458 - 2.783 0.381 - 536.6 1 2 0 -0.0005 11 0 0 0 5.19E+07 4.06E+07 - - - 5.6953 0.9459 221125_WJC_METTL3_EV_vs_WT_F05.11299.11299.3 0.222 Jul-40 K.AIFTQETIK[136.11]EK[136.11].E "sp|P82094|TMF1_HUMAN,tr|A0A2R8Y7M0|A0A2R8Y7M0_HUMAN" 2 1322.7417 1.12 63514 11299 3 1322.740493 441.9212 TATA element modulatory factor OS=Homo sapiens OX=9606 GN=TMF1 PE=1 SV=2 6.19 2262.8 - 1.51E+06 - - - -0.8876 - 1.477 0.195 - 50.9 2 2 1 -0.0012 11 0 0 0 1.77E+07 1.58E+07 - - - 1.6824 0.9997 221125_WJC_METTL3_EV_vs_WT_F05.11300.11300.2 0.118 13/16 K.KAVAISLPK.G "sp|P50454|SERPH_HUMAN,tr|E9PKH2|E9PKH2_HUMAN,tr|E9PPV6|E9PPV6_HUMAN,tr|E9PJH8|E9PJH8_HUMAN" 4 925.5961 1.96 63515 11300 2 925.59425 463.8053 Serpin H1 OS=Homo sapiens OX=9606 GN=SERPINH1 PE=1 SV=2 10 2262.9 - 1.18E+06 - - - -1.9479 - 2.492 0.37 - 619.1 1 2 0 -0.0018 9 0 0 0 1.38E+07 7.05E+06 - - - 4.4149 0.9742 221125_WJC_METTL3_EV_vs_WT_F05.11301.11301.2 0.00114 18-Oct T.RLEQEIATYR.R "sp|Q04695|K1C17_HUMAN,sp|P02533|K1C14_HUMAN,sp|P08727|K1C19_HUMAN,sp|P35900|K1C20_HUMAN,sp|P08779|K1C16_HUMAN,sp|P19012|K1C15_HUMAN,sp|Q8N1A0|KT222_HUMAN,sp|P13646|K1C13_HUMAN,tr|A0A3B3IS58|A0A3B3IS58_HUMAN,tr|F5GWP8|F5GWP8_HUMAN,tr|K7ERE3|K7ERE3_HUMAN,tr|A8MT21|A8MT21_HUMAN" 12 1277.6728 9.4 63516 11301 2 1277.671493 639.8437 "Keratin, type I cytoskeletal 17 OS=Homo sapiens OX=9606 GN=KRT17 PE=1 SV=2" 6.14 2263 - 746029 - - - -1.023 - 2.028 0.317 - 123.1 1 1 0 -0.0013 10 0 0 0 1.25E+07 1.33E+06 - - - 3.3555 0.9897 221125_WJC_METTL3_EV_vs_WT_F05.11302.11302.2 5.90E-07 22-Sep R.EIVHLQAGQC[160.03]GN.Q "sp|P04350|TBB4A_HUMAN,sp|Q9BVA1|TBB2B_HUMAN,sp|P07437|TBB5_HUMAN,sp|Q13509|TBB3_HUMAN,sp|Q13885|TBB2A_HUMAN,sp|P68371|TBB4B_HUMAN,sp|Q9BUF5|TBB6_HUMAN,tr|K7EJZ4|K7EJZ4_HUMAN,tr|M0R2D3|M0R2D3_HUMAN,tr|G3V3W7|G3V3W7_HUMAN,tr|K7EQT3|K7EQT3_HUMAN,tr|K7EN98|K7EN98_HUMAN,tr|M0R2T4|M0R2T4_HUMAN,tr|G3V3R4|G3V3R4_HUMAN,tr|M0R042|M0R042_HUMAN,tr|M0QY85|M0QY85_HUMAN,tr|M0QZL7|M0QZL7_HUMAN,tr|K7ESM5|K7ESM5_HUMAN,tr|G3V5W4|G3V5W4_HUMAN,tr|M0R0X0|M0R0X0_HUMAN,tr|K7ERA8|K7ERA8_HUMAN,tr|M0QYM7|M0QYM7_HUMAN,tr|K7ESQ3|K7ESQ3_HUMAN,tr|G3V4U2|G3V4U2_HUMAN,tr|M0R278|M0R278_HUMAN,tr|K7EL29|K7EL29_HUMAN,tr|M0QY37|M0QY37_HUMAN,tr|G3V2R8|G3V2R8_HUMAN,tr|G3V3J6|G3V3J6_HUMAN,tr|M0QX14|M0QX14_HUMAN,tr|K7EPE5|K7EPE5_HUMAN,tr|G3V2N6|G3V2N6_HUMAN,tr|K7EJ64|K7EJ64_HUMAN" 33 1324.6194 - 63517 11302 2 1324.616849 663.317 Tubulin beta-4A chain OS=Homo sapiens OX=9606 GN=TUBB4A PE=1 SV=2 5.24 2263.2 - 620219 - - - -1.9138 - 2.282 0.596 - 325.4 1 1 0 -0.0025 12 0 0 0 - - - - - 5.6131 0.9972 221125_WJC_METTL3_EV_vs_WT_F05.11306.11306.3 0.00421 Aug-36 R.LK[136.11]VEELEGER[166.11].S sp|Q9Y6D9|MD1L1_HUMAN 1 1218.6575 1.75 63520 11306 3 1218.655443 407.2264 Mitotic spindle assembly checkpoint protein MAD1 OS=Homo sapiens OX=9606 GN=MAD1L1 PE=1 SV=2 4.49 2263.6 - 913123 - - - -1.6773 - 1.74 0.341 - 91.2 1 2 1 -0.002 10 0 0 0 5.55E+07 3.17E+07 - - - 3.9588 1 221125_WJC_METTL3_EV_vs_WT_F05.11311.11311.2 0.000319 15/22 K.DAALATALGDKK.S "sp|P20700|LMNB1_HUMAN,tr|A0A0D9SFY5|A0A0D9SFY5_HUMAN,tr|E9PBF6|E9PBF6_HUMAN,tr|A0A0D9SFE5|A0A0D9SFE5_HUMAN" 4 1172.6401 1.24 63524 11311 2 1172.639096 587.3273 Lamin-B1 OS=Homo sapiens OX=9606 GN=LMNB1 PE=1 SV=2 5.96 2264.1 - 1.94E+06 - - - -0.8579 - 2.954 0.526 - 901.9 1 2 0 -0.001 12 0 0 0 7.46E+07 6.03E+07 - - - 5.7757 1 221125_WJC_METTL3_EV_vs_WT_F05.11315.11315.3 1.31E-06 Dec-44 K.DAALATALGDKK.S "sp|P20700|LMNB1_HUMAN,tr|A0A0D9SFY5|A0A0D9SFY5_HUMAN,tr|E9PBF6|E9PBF6_HUMAN,tr|A0A0D9SFE5|A0A0D9SFE5_HUMAN" 4 1172.6401 1.24 63526 11315 3 1172.638041 391.8873 Lamin-B1 OS=Homo sapiens OX=9606 GN=LMNB1 PE=1 SV=2 5.96 2264.6 - 6.79E+06 - - - -1.7576 - 2.578 0.504 - 184.8 1 2 0 -0.0021 12 0 0 0 1.52E+08 1.23E+08 - - - 6.7835 0.9999 221125_WJC_METTL3_EV_vs_WT_F05.11317.11317.2 0.00245 14/22 K.DAALATALGDK[136.11]K[136.11].S "sp|P20700|LMNB1_HUMAN,tr|A0A0D9SFY5|A0A0D9SFY5_HUMAN,tr|E9PBF6|E9PBF6_HUMAN,tr|A0A0D9SFE5|A0A0D9SFE5_HUMAN" 4 1188.6685 1.24 63528 11317 2 1188.667743 595.3415 Lamin-B1 OS=Homo sapiens OX=9606 GN=LMNB1 PE=1 SV=2 5.96 2264.8 - 2.17E+06 - - - -0.6385 - 2.86 0.487 - 793.9 1 2 0 -0.0008 12 0 0 0 7.46E+07 6.03E+07 - - - 5.4026 0.9999 221125_WJC_METTL3_EV_vs_WT_F05.11318.11318.3 2.78E-05 Dec-48 K.AALEAQNALHNMK[136.11].V "sp|Q92879|CELF1_HUMAN,tr|G5EA30|G5EA30_HUMAN,tr|E9PSH0|E9PSH0_HUMAN,tr|E9PQK4|E9PQK4_HUMAN,tr|E9PKU1|E9PKU1_HUMAN" 5 1417.7227 1.21 63529 11318 3 1417.720371 473.5815 CUGBP Elav-like family member 1 OS=Homo sapiens OX=9606 GN=CELF1 PE=1 SV=2 6.79 2264.8 - 1.76E+06 - - - -1.6661 - 2.667 0.457 - 234.1 1 2 0 -0.0024 13 0 0 0 4.84E+07 3.98E+07 - - - 6.2941 0.9999 221125_WJC_METTL3_EV_vs_WT_F05.11319.11319.3 0.000121 16/64 R.GSGGLGGAC[160.03]GGAGFGSR.S "sp|P48668|K2C6C_HUMAN,sp|P04259|K2C6B_HUMAN,sp|P02538|K2C6A_HUMAN" 3 1423.6263 999 63530 11319 3 1423.621663 475.5494 "Keratin, type II cytoskeletal 6C OS=Homo sapiens OX=9606 GN=KRT6C PE=1 SV=3" 8.25 2264.9 - 1.25E+06 - - - -3.2291 - 2.959 0.59 - 335.8 1 2 0 -0.0046 17 0 0 0 1.10E+08 0.00E+00 - - - 7.8573 0.9998 221125_WJC_METTL3_EV_vs_WT_F05.11326.11326.3 0.0294 14/40 R.VTK[136.11]PNIPEAIR[166.11].R "sp|O94905|ERLN2_HUMAN,tr|E5RHW4|E5RHW4_HUMAN,tr|E5RJ09|E5RJ09_HUMAN" 3 1254.7415 1.22 63535 11326 3 1254.74018 419.2544 Erlin-2 OS=Homo sapiens OX=9606 GN=ERLIN2 PE=1 SV=1 8.72 2265.9 - 898274 - - - -1.0448 - 2.35 0.346 - 304.1 1 2 0 -0.0013 11 0 0 0 3.30E+07 2.70E+07 - - - 4.8244 0.9993 221125_WJC_METTL3_EV_vs_WT_F05.11329.11329.2 0.0277 18-Oct R.RLPENLYNDR.M "sp|P14927|QCR7_HUMAN,tr|E5RHG9|E5RHG9_HUMAN,tr|B7Z2R2|B7Z2R2_HUMAN" 3 1288.6524 4.48 63538 11329 2 1288.653152 645.3335 Cytochrome b-c1 complex subunit 7 OS=Homo sapiens OX=9606 GN=UQCRB PE=1 SV=2 6.07 2266.1 - 342812 - - - 0.5851 - 1.893 0.265 - 147.3 1 2 0 0.0008 10 0 0 0 1.08E+07 2.41E+06 - - - 2.7794 0.9996 221125_WJC_METTL3_EV_vs_WT_F05.11330.11330.2 0.00111 20-Oct R.GSYQLQAQMNR.A sp|Q9H1Z4|WDR13_HUMAN 1 1294.6088 1.34 63539 11330 2 1294.607714 648.3117 WD repeat-containing protein 13 OS=Homo sapiens OX=9606 GN=WDR13 PE=1 SV=2 8.75 2266.3 - 268918 - - - -0.8535 - 1.774 0.388 - 283.7 1 2 0 -0.0011 11 0 0 0 1.67E+07 1.25E+07 - - - 3.4572 0.9999 221125_WJC_METTL3_EV_vs_WT_F05.11334.11334.3 1.48E-06 13/32 K.HGINC[160.03]FINR[166.11].Q "sp|P78371|TCPB_HUMAN,tr|F8VQ14|F8VQ14_HUMAN,tr|F5GWF6|F5GWF6_HUMAN" 3 1139.5534 0.001 63541 11334 3 1139.552401 380.8584 T-complex protein 1 subunit beta OS=Homo sapiens OX=9606 GN=CCT2 PE=1 SV=4 8.26 2266.7 - 4.03E+06 - - - -0.8477 - 2.09 0.38 - 309.6 1 2 0 -0.001 9 0 0 0 0.00E+00 8.69E+07 - - - 4.998 0.9954 221125_WJC_METTL3_EV_vs_WT_F05.11335.11335.3 0.23 Nov-36 R.LKYENEVALR.Q "sp|P13645|K1C10_HUMAN,tr|A0A1B0GVI3|A0A1B0GVI3_HUMAN" 2 1233.6717 12.2 63542 11335 3 1233.669702 412.2312 "Keratin, type I cytoskeletal 10 OS=Homo sapiens OX=9606 GN=KRT10 PE=1 SV=6" 6.14 2266.8 - 3.74E+06 - - - -1.6495 - 1.833 0.292 - 97.8 1 2 1 -0.002 10 0 0 0 1.19E+09 9.75E+07 - - - 3.5646 1 221125_WJC_METTL3_EV_vs_WT_F05.11344.11344.3 0.000294 17/44 K.DAALATALGDK[136.11]K[136.11].S "sp|P20700|LMNB1_HUMAN,tr|A0A0D9SFY5|A0A0D9SFY5_HUMAN,tr|E9PBF6|E9PBF6_HUMAN,tr|A0A0D9SFE5|A0A0D9SFE5_HUMAN" 4 1188.6685 1.24 63549 11344 3 1188.665936 397.2301 Lamin-B1 OS=Homo sapiens OX=9606 GN=LMNB1 PE=1 SV=2 5.96 2267.8 - 6.95E+06 - - - -2.1587 - 3.053 0.507 - 411.7 1 2 0 -0.0026 12 0 0 0 1.53E+08 1.24E+08 - - - 7.2856 0.9999 221125_WJC_METTL3_EV_vs_WT_F05.11345.11345.2 5.18E-05 16-Dec K.HGINC[160.03]FINR[166.11].Q "sp|P78371|TCPB_HUMAN,tr|F8VQ14|F8VQ14_HUMAN,tr|F5GWF6|F5GWF6_HUMAN" 3 1139.5534 0.32 63550 11345 2 1139.552414 570.784 T-complex protein 1 subunit beta OS=Homo sapiens OX=9606 GN=CCT2 PE=1 SV=4 8.26 2267.8 - 6.16E+06 - - - -0.8363 - 2.114 0.537 - 385.1 1 2 0 -0.001 9 0 0 0 4.64E+07 1.47E+08 - - - 5.1727 0.9978 221125_WJC_METTL3_EV_vs_WT_F05.11346.11346.2 0.000292 18-Oct R.LKYENEVALR.Q "sp|P13645|K1C10_HUMAN,tr|A0A1B0GVI3|A0A1B0GVI3_HUMAN" 2 1233.6717 41.75 63551 11346 2 1233.672949 617.8431 "Keratin, type I cytoskeletal 10 OS=Homo sapiens OX=9606 GN=KRT10 PE=1 SV=6" 6.14 2268 - 1.06E+06 - - - 0.9824 - 2.089 0.46 - 243.1 1 2 1 0.0012 10 0 0 0 1.94E+08 4.64E+06 - - - 4.4945 0.9993 221125_WJC_METTL3_EV_vs_WT_F05.11349.11349.2 3.94E-05 26-Dec R.LAASASTQQLQEVK[136.11].A sp|O95235|KI20A_HUMAN 1 1480.7977 1.16 63554 11349 2 1480.792915 741.4061 Kinesin-like protein KIF20A OS=Homo sapiens OX=9606 GN=KIF20A PE=1 SV=1 6 2268.4 - 505548 - - - -3.2125 - 2.566 0.444 - 354.2 1 2 0 -0.0048 14 0 0 0 9.84E+06 8.49E+06 - - - 4.6837 1 221125_WJC_METTL3_EV_vs_WT_F05.11355.11355.2 5.75E-06 16/22 R.K[136.11]FGDPVVQSDMK[136.11].H "sp|P0DMV8|HS71A_HUMAN,sp|P0DMV9|HS71B_HUMAN,tr|A0A0G2JIW1|A0A0G2JIW1_HUMAN" 3 1365.6933 0.14 63557 11355 2 1365.692773 683.8539 Heat shock 70 kDa protein 1A OS=Homo sapiens OX=9606 GN=HSPA1A PE=1 SV=1 5.96 2269.1 - 1.52E+06 - - - -0.413 - 3.123 0.566 - 867.3 1 2 0 -0.0006 12 0 0 0 5.55E+07 4.08E+08 - - - 6.2177 0.9998 221125_WJC_METTL3_EV_vs_WT_F05.11357.11357.3 0.000678 Dec-36 K.GTYLATFHQR[166.11].G "sp|P55884|EIF3B_HUMAN,tr|C9JQN7|C9JQN7_HUMAN" 2 1202.6072 1.02 63559 11357 3 1202.604781 401.8763 Eukaryotic translation initiation factor 3 subunit B OS=Homo sapiens OX=9606 GN=EIF3B PE=1 SV=3 8.75 2269.3 - 1.16E+06 - - - -1.9915 - 1.73 0.461 - 176.4 1 2 0 -0.0024 10 0 0 0 1.98E+07 1.95E+07 - - - 5.2798 1 221125_WJC_METTL3_EV_vs_WT_F05.11358.11358.3 5.30E-09 14/44 K.STEHNMGLALTR.N sp|Q10469|MGAT2_HUMAN 1 1328.6507 0.92 63560 11358 3 1328.647071 443.8908 "Alpha-1,6-mannosyl-glycoprotein 2-beta-N-acetylglucosaminyltransferase OS=Homo sapiens OX=9606 GN=MGAT2 PE=1 SV=1" 6.47 2269.4 - 1.02E+06 - - - -2.7193 - 2.719 0.581 - 359.3 1 2 0 -0.0036 12 0 0 0 4.91E+07 5.32E+07 - - - 7.7892 0.9949 221125_WJC_METTL3_EV_vs_WT_F05.11359.11359.2 2.14E-05 20-Dec R.GSYQLQAQMNR[166.11].A sp|Q9H1Z4|WDR13_HUMAN 1 1304.6171 1.34 63561 11359 2 1304.610711 653.3158 WD repeat-containing protein 13 OS=Homo sapiens OX=9606 GN=WDR13 PE=1 SV=2 8.75 2269.5 - 953564 - - - -4.8888 - 1.952 0.375 - 456.7 1 2 0 -0.0064 11 0 0 0 1.67E+07 1.25E+07 - - - 3.6182 0.9998 221125_WJC_METTL3_EV_vs_WT_F05.11363.11363.2 3.13E-05 18-Sep R.STSSFSC[160.03]LSR.H sp|P35908|K22E_HUMAN 1 1130.5026 40.75 63564 11363 2 1130.501359 566.2586 "Keratin, type II cytoskeletal 2 epidermal OS=Homo sapiens OX=9606 GN=KRT2 PE=1 SV=2" 7.96 2270 - 1.59E+08 - - - -1.1181 - 1.987 0.444 - 448.3 1 2 0 -0.0013 10 0 0 0 3.04E+09 7.45E+07 - - - 4.2366 0.9998 221125_WJC_METTL3_EV_vs_WT_F05.11365.11365.2 2.92E-05 18-Oct K.QC[160.03]GNLTEDLK.T "sp|P52732|KIF11_HUMAN,tr|A0A7I2V3A9|A0A7I2V3A9_HUMAN" 2 1176.5445 4.19 63565 11365 2 1176.542979 589.2795 Kinesin-like protein KIF11 OS=Homo sapiens OX=9606 GN=KIF11 PE=1 SV=2 4.37 2270.2 - 6.11E+06 - - - -1.2826 - 2.369 0.486 - 518 1 2 0 -0.0015 10 0 0 0 2.99E+08 7.14E+07 - - - 5.0375 1 221125_WJC_METTL3_EV_vs_WT_F05.11368.11368.3 9.40E-06 19/52 R.AIGTDEDLAHSSIR[166.11].F "sp|Q9Y697|NFS1_HUMAN,tr|H0YGN5|H0YGN5_HUMAN,tr|H7C0I5|H7C0I5_HUMAN" 3 1493.735 0.79 63568 11368 3 1493.73316 498.9189 "Cysteine desulfurase, mitochondrial OS=Homo sapiens OX=9606 GN=NFS1 PE=1 SV=3" 4.54 2270.4 - 945689 - - - -1.2024 - 2.958 0.514 - 477.7 1 2 0 -0.0018 14 0 0 0 9.72E+06 1.22E+07 - - - 7.1522 0.9993 221125_WJC_METTL3_EV_vs_WT_F05.11369.11369.3 0.126 13/52 R.HVLDNPTPEMEAAR.R "sp|Q8ND83|SLAI1_HUMAN,tr|A0A0A0MSS3|A0A0A0MSS3_HUMAN,tr|Q5T6P5|Q5T6P5_HUMAN" 3 1578.746 0.96 63569 11369 3 1578.746753 527.256 SLAIN motif-containing protein 1 OS=Homo sapiens OX=9606 GN=SLAIN1 PE=1 SV=3 4.65 2270.6 - 645530 - - - 0.451 - 1.998 0.29 - 252.1 1 2 0 0.0007 14 0 0 0 1.04E+07 1.08E+07 - - - 3.6124 0.9957 221125_WJC_METTL3_EV_vs_WT_F05.11374.11374.3 0.107 Aug-56 R.APSTYGGGLSVSSSR.F sp|P02533|K1C14_HUMAN 1 1424.6896 186.11 63572 11374 3 1424.688705 475.9038 "Keratin, type I cytoskeletal 14 OS=Homo sapiens OX=9606 GN=KRT14 PE=1 SV=4" 8.79 2271.1 - 5.54E+06 - - - -0.6086 - 1.687 0.23 - 73.8 2 2 0 -0.0009 15 0 0 0 2.95E+08 1.59E+06 - - - 2.3293 0.9997 221125_WJC_METTL3_EV_vs_WT_F05.11379.11379.2 0.00122 26-Nov R.LAASASTQQLQEVK.A sp|O95235|KI20A_HUMAN 1 1472.7835 1.16 63575 11379 2 1472.781056 737.399 Kinesin-like protein KIF20A OS=Homo sapiens OX=9606 GN=KIF20A PE=1 SV=1 6 2271.8 - 556066 - - - -1.6404 - 2.572 0.42 - 319.9 1 2 0 -0.0024 14 0 0 0 9.84E+06 8.49E+06 - - - 4.513 0.9998 221125_WJC_METTL3_EV_vs_WT_F05.11384.11384.2 4.79E-07 13/28 R.APSTYGGGLSVSSSR.F sp|P02533|K1C14_HUMAN 1 1424.6896 8543.74 63578 11384 2 1424.686351 713.3521 "Keratin, type I cytoskeletal 14 OS=Homo sapiens OX=9606 GN=KRT14 PE=1 SV=4" 8.79 2272.4 - 1.48E+08 - - - -2.2608 - 2.693 0.567 - 462.4 1 2 0 -0.0032 15 0 0 0 4.78E+09 5.60E+05 - - - 5.6634 0.9999 221125_WJC_METTL3_EV_vs_WT_F05.11386.11386.3 0.0119 Oct-36 K.GTYLATFHQR.G "sp|P55884|EIF3B_HUMAN,tr|C9JQN7|C9JQN7_HUMAN" 2 1192.5989 1.01 63580 11386 3 1192.597244 398.5402 Eukaryotic translation initiation factor 3 subunit B OS=Homo sapiens OX=9606 GN=EIF3B PE=1 SV=3 8.75 2272.6 - 1.55E+06 - - - -1.3936 - 2.269 0.369 - 143.8 1 2 0 -0.0017 10 0 0 0 1.98E+07 1.96E+07 - - - 5.0464 0.9998 221125_WJC_METTL3_EV_vs_WT_F05.11388.11388.3 0.019 Dec-52 R.HVLDNPTPEMEAAR[166.11].R "sp|Q8ND83|SLAI1_HUMAN,tr|A0A0A0MSS3|A0A0A0MSS3_HUMAN,tr|Q5T6P5|Q5T6P5_HUMAN" 3 1588.7543 0.95 63582 11388 3 1588.753507 530.592 SLAIN motif-containing protein 1 OS=Homo sapiens OX=9606 GN=SLAIN1 PE=1 SV=3 4.65 2272.8 - 452447 - - - -0.5061 - 2.368 0.331 - 194.9 1 2 0 -0.0008 14 0 0 0 1.04E+07 1.10E+07 - - - 4.521 0.9997 221125_WJC_METTL3_EV_vs_WT_F05.11394.11394.2 0.000161 20-Sep R.AENYDIPSADR.H "sp|P22314|UBA1_HUMAN,tr|Q5JRR6|Q5JRR6_HUMAN" 2 1249.5575 0.54 63586 11394 2 1249.555483 625.786 Ubiquitin-like modifier-activating enzyme 1 OS=Homo sapiens OX=9606 GN=UBA1 PE=1 SV=3 4.03 2273.5 - 520011 - - - -1.6102 - 2 0.42 - 307 1 2 0 -0.002 11 0 0 0 1.53E+07 2.82E+07 - - - 4.0176 0.9999 221125_WJC_METTL3_EV_vs_WT_F05.11395.11395.2 5.49E-07 20-Dec R.AENYDIPSADR[166.11].H "sp|P22314|UBA1_HUMAN,tr|Q5JRR6|Q5JRR6_HUMAN" 2 1259.5658 0.54 63587 11395 2 1259.56528 630.7902 Ubiquitin-like modifier-activating enzyme 1 OS=Homo sapiens OX=9606 GN=UBA1 PE=1 SV=3 4.03 2273.7 - 1.34E+06 - - - -0.3851 - 2.333 0.486 - 475.5 1 2 0 -0.0005 11 0 0 0 1.53E+07 2.82E+07 - - - 4.9222 0.9998 221125_WJC_METTL3_EV_vs_WT_F05.11396.11396.2 0.00198 22-Nov K.SVQTTLQTDEVK[136.11].N "sp|O94905|ERLN2_HUMAN,sp|O75477|ERLN1_HUMAN,tr|E5RHW4|E5RHW4_HUMAN,tr|B0QZ43|B0QZ43_HUMAN" 4 1355.7024 1.39 63588 11396 2 1355.702333 678.8585 Erlin-2 OS=Homo sapiens OX=9606 GN=ERLIN2 PE=1 SV=1 4.37 2273.8 - 837992 - - - -0.031 - 2.118 0.446 - 185.4 1 2 0 0 12 0 0 0 1.44E+07 1.04E+07 - - - 4.3098 0.9981 221125_WJC_METTL3_EV_vs_WT_F05.11398.11398.3 0.00801 Nov-40 K.DLVAQAPLK[136.11]PK[136.11].T sp|O94776|MTA2_HUMAN 1 1194.7307 0.73 63590 11398 3 1194.726831 399.2508 Metastasis-associated protein MTA2 OS=Homo sapiens OX=9606 GN=MTA2 PE=1 SV=1 8.59 2274 - 728288 - - - -3.2459 - 1.712 0.35 - 141 1 2 0 -0.0039 11 0 0 0 8.13E+06 1.11E+07 - - - 3.9685 1 221125_WJC_METTL3_EV_vs_WT_F05.11400.11400.3 0.000174 15/44 R.KAGNFYVPAEPK.L "sp|P18124|RL7_HUMAN,tr|C9JIJ5|C9JIJ5_HUMAN,tr|C9JZ88|C9JZ88_HUMAN,tr|A8MUD9|A8MUD9_HUMAN" 4 1319.6874 0.25 63592 11400 3 1319.687786 440.9031 60S ribosomal protein L7 OS=Homo sapiens OX=9606 GN=RPL7 PE=1 SV=1 8.5 2274.3 - 506847 - - - 0.3023 - 2.227 0.511 - 262.1 1 2 0 0.0004 12 0 0 0 1.71E+07 6.85E+07 - - - 6.4563 0.9967 221125_WJC_METTL3_EV_vs_WT_F05.11405.11405.3 0.000206 Dec-60 R.LANGLGREEAVAEGAR.R sp|Q8IU81|I2BP1_HUMAN 1 1611.8329 1.41 63595 11405 3 1611.826007 538.2849 Interferon regulatory factor 2-binding protein 1 OS=Homo sapiens OX=9606 GN=IRF2BP1 PE=1 SV=1 4.79 2274.9 - 711000 - - - -4.2653 - 2.307 0.428 - 189 1 2 1 -0.0069 16 0 0 0 6.97E+06 4.94E+06 - - - 5.4548 0.9998 221125_WJC_METTL3_EV_vs_WT_F05.11408.11408.2 0.0049 20-Nov K.SQQASVLQGYK.N "sp|Q6N021|TET2_HUMAN,tr|E7EQS8|E7EQS8_HUMAN,tr|E7EPB1|E7EPB1_HUMAN" 3 1207.6197 4.87 63598 11408 2 1207.619018 604.8171 Methylcytosine dioxygenase TET2 OS=Homo sapiens OX=9606 GN=TET2 PE=1 SV=3 8.31 2275.3 - 454048 - - - -0.5656 - 2.081 0.446 - 439.4 1 2 0 -0.0007 11 0 0 0 1.36E+07 2.79E+06 - - - 4.3175 0.9943 221125_WJC_METTL3_EV_vs_WT_F05.11409.11409.2 0.0161 20-Sep K.LITDLQDQNQK.M sp|P33176|KINH_HUMAN 1 1314.6779 2.58 63599 11409 2 1314.672379 658.3462 Kinesin-1 heavy chain OS=Homo sapiens OX=9606 GN=KIF5B PE=1 SV=1 4.21 2275.4 - 436277 - - - -4.2337 - 1.909 0.297 - 204.2 1 2 0 -0.0056 11 0 0 0 6.24E+06 2.42E+06 - - - 2.982 0.9999 221125_WJC_METTL3_EV_vs_WT_F05.11414.11414.3 0.00465 13/44 R.YLMEEDEDAYK[136.11]K[136.11].Q "sp|P46777|RL5_HUMAN,tr|A0A2R8Y6J3|A0A2R8Y6J3_HUMAN" 2 1548.6989 2.35 63602 11414 3 1548.702098 517.2402 60S ribosomal protein L5 OS=Homo sapiens OX=9606 GN=RPL5 PE=1 SV=3 4.18 2275.9 - 1.53E+06 - - - 2.0805 - 2.36 0.511 - 145.8 1 2 0 0.0032 12 0 0 0 1.99E+07 8.49E+06 - - - 6.6163 0.9999 221125_WJC_METTL3_EV_vs_WT_F05.11415.11415.2 5.17E-05 24-Dec K.TTLSASGTGFGDK.F sp|P49790|NU153_HUMAN 1 1240.5935 1.35 63603 11415 2 1240.593349 621.304 Nuclear pore complex protein Nup153 OS=Homo sapiens OX=9606 GN=NUP153 PE=1 SV=2 5.5 2276 - 1.43E+06 - - - -0.1588 - 2.285 0.502 - 212.9 1 2 0 -0.0002 13 0 0 0 2.98E+07 2.21E+07 - - - 4.8696 1 221125_WJC_METTL3_EV_vs_WT_F05.11416.11416.3 0.00906 17/48 R.VVQVVKPHTPLIR.F sp|P82909|RT36_HUMAN 1 1484.9191 1.62 63604 11416 3 1484.917751 495.9803 "28S ribosomal protein S36, mitochondrial OS=Homo sapiens OX=9606 GN=MRPS36 PE=1 SV=2" 11 2276.1 - 1.03E+06 - - - -0.9206 - 2.527 0.459 - 374.3 1 2 0 -0.0014 13 0 0 0 3.62E+07 2.24E+07 - - - 6.1705 0.9994 221125_WJC_METTL3_EV_vs_WT_F05.11418.11418.3 2.58 Oct-36 K.K[136.11]QLADETLLK[136.11].V "sp|P20700|LMNB1_HUMAN,tr|E9PBF6|E9PBF6_HUMAN,tr|A0A0D9SFE5|A0A0D9SFE5_HUMAN" 3 1173.694 1.81 63606 11418 3 1173.692044 392.2386 Lamin-B1 OS=Homo sapiens OX=9606 GN=LMNB1 PE=1 SV=2 6.07 2276.4 - 796844 - - - -1.6572 - 2.166 0.281 - 158.5 1 2 0 -0.0019 10 0 0 0 2.18E+07 1.21E+07 - - - 3.9295 1 221125_WJC_METTL3_EV_vs_WT_F05.11422.11422.3 4.06E-06 13/44 R.YLMEEDEDAYKK.Q "sp|P46777|RL5_HUMAN,tr|A0A2R8Y6J3|A0A2R8Y6J3_HUMAN" 2 1532.6705 2.41 63608 11422 3 1532.667729 511.8974 60S ribosomal protein L5 OS=Homo sapiens OX=9606 GN=RPL5 PE=1 SV=3 4.18 2276.9 - 2.45E+06 - - - -1.7923 - 2.28 0.626 - 140.7 1 2 0 -0.0027 12 0 0 0 2.05E+07 8.49E+06 - - - 7.803 0.9997 221125_WJC_METTL3_EV_vs_WT_F05.11423.11423.3 0.00387 15/44 R.DNIQGITK[136.11]PAIR[166.11].R sp|P62805|H4_HUMAN 1 1342.7688 1.19 63609 11423 3 1342.767025 448.5969 Histone H4 OS=Homo sapiens OX=9606 GN=H4C1 PE=1 SV=2 8.75 2276.9 - 1.97E+06 - - - -1.2988 - 2.176 0.34 - 392.4 1 2 0 -0.0017 12 0 0 0 1.31E+08 1.10E+08 - - - 4.4853 0.9756 221125_WJC_METTL3_EV_vs_WT_F05.11426.11426.2 0.00478 16-Oct L.KYENEVALR.Q "sp|P13645|K1C10_HUMAN,tr|A0A1B0GVI3|A0A1B0GVI3_HUMAN" 2 1120.5877 16.23 63612 11426 2 1120.586758 561.3011 "Keratin, type I cytoskeletal 10 OS=Homo sapiens OX=9606 GN=KRT10 PE=1 SV=6" 6.14 2277.3 - 915193 - - - -0.8165 - 1.846 0.341 - 411.2 1 1 0 -0.0009 9 0 0 0 1.70E+07 1.05E+06 - - - 3.3328 0.9936 221125_WJC_METTL3_EV_vs_WT_F05.11433.11433.3 0.0647 Dec-48 R.KVIEEQLEPAVEK.L "sp|P42704|LPPRC_HUMAN,tr|A0A804HI14|A0A804HI14_HUMAN,tr|A0A804HL40|A0A804HL40_HUMAN,tr|A0A804HKJ0|A0A804HKJ0_HUMAN,tr|A0A804HKR3|A0A804HKR3_HUMAN,tr|A0A804HIN4|A0A804HIN4_HUMAN,tr|H7C3W8|H7C3W8_HUMAN,tr|A0A804HLG8|A0A804HLG8_HUMAN,tr|A0A804HJA1|A0A804HJA1_HUMAN,tr|A0A804HHY9|A0A804HHY9_HUMAN,tr|A0A804HI40|A0A804HI40_HUMAN,tr|A0A804HJZ1|A0A804HJZ1_HUMAN,tr|A0A804HIQ7|A0A804HIQ7_HUMAN,tr|A0A804HK30|A0A804HK30_HUMAN,tr|A0A804HKI2|A0A804HKI2_HUMAN,tr|A0A804HJI0|A0A804HJI0_HUMAN,tr|A0A804HKK7|A0A804HKK7_HUMAN,tr|A0A804HIG4|A0A804HIG4_HUMAN" 18 1510.8243 0.66 63619 11433 3 1510.82084 504.6154 "Leucine-rich PPR motif-containing protein, mitochondrial OS=Homo sapiens OX=9606 GN=LRPPRC PE=1 SV=3" 4.49 2278.2 - 1.08E+06 - - - -2.2729 - 2.106 0.181 - 186.4 1 2 0 -0.0034 13 0 0 0 4.72E+06 7.16E+06 - - - 2.5764 0.9999 221125_WJC_METTL3_EV_vs_WT_F05.11435.11435.2 2.20E-05 13/24 K.TTLSASGTGFGDK[136.11].F sp|P49790|NU153_HUMAN 1 1248.6077 1.35 63620 11435 2 1248.606774 625.3111 Nuclear pore complex protein Nup153 OS=Homo sapiens OX=9606 GN=NUP153 PE=1 SV=2 5.5 2278.4 - 1.70E+06 - - - -0.7785 - 2.296 0.518 - 619.4 1 2 0 -0.001 13 0 0 0 2.98E+07 2.21E+07 - - - 4.9999 0.9998 221125_WJC_METTL3_EV_vs_WT_F05.11438.11438.3 0.0107 Oct-40 K.DLLHPSPEEEK[136.11].R sp|P42677|RS27_HUMAN 1 1300.639 0.59 63622 11438 3 1300.635828 434.5536 40S ribosomal protein S27 OS=Homo sapiens OX=9606 GN=RPS27 PE=1 SV=3 4.4 2278.7 - 2.49E+06 - - - -2.4742 - 2.071 0.458 - 108.6 1 2 0 -0.0032 11 0 0 0 1.83E+08 3.11E+08 - - - 5.7136 0.9987 221125_WJC_METTL3_EV_vs_WT_F05.11440.11440.3 0.0611 14/52 K.SIIKEPESAAEAVK.L "sp|O76031|CLPX_HUMAN,tr|H0YK07|H0YK07_HUMAN,tr|H0YM48|H0YM48_HUMAN" 3 1470.793 0.83 63624 11440 3 1470.791206 491.2716 "ATP-dependent Clp protease ATP-binding subunit clpX-like, mitochondrial OS=Homo sapiens OX=9606 GN=CLPX PE=1 SV=2" 4.78 2278.9 - 1.40E+06 - - - -1.2021 - 2.325 0.32 - 127.7 1 2 1 -0.0018 14 0 0 0 1.53E+07 1.84E+07 - - - 4.3494 0.9991 221125_WJC_METTL3_EV_vs_WT_F05.11441.11441.2 0.000132 18-Aug K.QC[160.03]GNLTEDLK[136.11].T "sp|P52732|KIF11_HUMAN,tr|A0A7I2V3A9|A0A7I2V3A9_HUMAN" 2 1184.5587 4.51 63625 11441 2 1184.555197 593.2866 Kinesin-like protein KIF11 OS=Homo sapiens OX=9606 GN=KIF11 PE=1 SV=2 4.37 2279 - 1.26E+06 - - - -2.9471 - 1.974 0.423 - 262 1 2 0 -0.0035 10 0 0 0 2.98E+08 6.61E+07 - - - 4.0624 0.9998 221125_WJC_METTL3_EV_vs_WT_F05.11442.11442.3 0.000155 Dec-40 K.DLLHPSPEEEK.R sp|P42677|RS27_HUMAN 1 1292.6248 0.58 63626 11442 3 1292.621159 431.8822 40S ribosomal protein S27 OS=Homo sapiens OX=9606 GN=RPS27 PE=1 SV=3 4.4 2279.1 - 1.13E+06 - - - -2.8523 - 2.347 0.452 - 143.7 1 2 0 -0.0037 11 0 0 0 1.80E+08 3.10E+08 - - - 6.002 0.9994 221125_WJC_METTL3_EV_vs_WT_F05.11443.11443.3 0.00113 Aug-36 R.GHEEFPLDGR[166.11].N "sp|P49750|YLPM1_HUMAN,tr|H0YIQ2|H0YIQ2_HUMAN" 2 1165.5392 1.57 63627 11443 3 1165.537795 389.5203 YLP motif-containing protein 1 OS=Homo sapiens OX=9606 GN=YLPM1 PE=1 SV=4 4.65 2279.2 - 761827 - - - -1.1677 - 1.609 0.346 - 122.1 1 2 0 -0.0014 10 0 0 0 1.98E+07 1.26E+07 - - - 3.7862 1 221125_WJC_METTL3_EV_vs_WT_F05.11450.11450.2 2.38E-05 14/18 R.KESYSVYVYK.V "sp|Q5QNW6|H2B2F_HUMAN,sp|P58876|H2B1D_HUMAN,sp|Q99880|H2B1L_HUMAN,sp|P62807|H2B1C_HUMAN,sp|Q99877|H2B1N_HUMAN,sp|P57053|H2BFS_HUMAN,sp|O60814|H2B1K_HUMAN,sp|Q93079|H2B1H_HUMAN,sp|Q99879|H2B1M_HUMAN,tr|U3KQK0|U3KQK0_HUMAN" 10 1264.634 0.78 63632 11450 2 1264.631281 633.3243 Histone H2B type 2-F OS=Homo sapiens OX=9606 GN=H2BC18 PE=1 SV=3 8.38 2280.1 - 1.85E+06 - - - -2.1137 - 2.775 0.563 - 641.3 1 2 0 -0.0027 10 0 0 0 5.29E+07 6.76E+07 - - - 6.0474 1 221125_WJC_METTL3_EV_vs_WT_F05.11451.11451.3 6.67E-05 17/48 R.VVQVVK[136.11]PHTPLIR[166.11].F sp|P82909|RT36_HUMAN 1 1502.9416 1.62 63633 11451 3 1502.939668 501.9878 "28S ribosomal protein S36, mitochondrial OS=Homo sapiens OX=9606 GN=MRPS36 PE=1 SV=2" 11 2280.2 - 966771 - - - -1.2775 - 2.812 0.503 - 375.8 1 2 0 -0.0019 13 0 0 0 3.62E+07 2.24E+07 - - - 6.9506 0.9999 221125_WJC_METTL3_EV_vs_WT_F05.11452.11452.3 0.000163 Oct-36 R.KESYSVYVYK.V "sp|Q5QNW6|H2B2F_HUMAN,sp|P58876|H2B1D_HUMAN,sp|Q99880|H2B1L_HUMAN,sp|P62807|H2B1C_HUMAN,sp|Q99877|H2B1N_HUMAN,sp|P57053|H2BFS_HUMAN,sp|O60814|H2B1K_HUMAN,sp|Q93079|H2B1H_HUMAN,sp|Q99879|H2B1M_HUMAN,tr|U3KQK0|U3KQK0_HUMAN" 10 1264.634 0.28 63634 11452 3 1264.631468 422.5519 Histone H2B type 2-F OS=Homo sapiens OX=9606 GN=H2BC18 PE=1 SV=3 8.38 2280.3 - 7.85E+06 - - - -1.9658 - 1.937 0.516 - 152.6 1 2 0 -0.0025 10 0 0 0 3.59E+08 1.28E+09 - - - 6.223 0.9997 221125_WJC_METTL3_EV_vs_WT_F05.11453.11453.3 0.000487 Oct-36 R.GHEEFPLDGR.N "sp|P49750|YLPM1_HUMAN,tr|H0YIQ2|H0YIQ2_HUMAN" 2 1155.5309 1.57 63635 11453 3 1155.527245 386.1842 YLP motif-containing protein 1 OS=Homo sapiens OX=9606 GN=YLPM1 PE=1 SV=4 4.65 2280.4 - 992065 - - - -3.1509 - 2.203 0.41 - 215.5 1 2 0 -0.0036 10 0 0 0 1.98E+07 1.26E+07 - - - 5.4167 0.9999 221125_WJC_METTL3_EV_vs_WT_F05.11456.11456.2 9.36E-07 22-Nov R.AQNISSNANMLR.K sp|Q14008|CKAP5_HUMAN 1 1317.6459 1.1 63638 11456 2 1317.645839 659.8302 Cytoskeleton-associated protein 5 OS=Homo sapiens OX=9606 GN=CKAP5 PE=1 SV=3 9.79 2280.8 - 609796 - - - -0.0713 - 2.128 0.541 - 462.1 1 2 0 -0.0001 12 0 0 0 4.90E+06 4.46E+06 - - - 5.0238 0.97 221125_WJC_METTL3_EV_vs_WT_F05.11457.11457.2 0.000486 22-Nov R.AQNISSNANMLR[166.11].K sp|Q14008|CKAP5_HUMAN 1 1327.6542 1.13 63639 11457 2 1327.662473 664.8344 Cytoskeleton-associated protein 5 OS=Homo sapiens OX=9606 GN=CKAP5 PE=1 SV=3 9.79 2280.9 - 525370 - - - 6.229 - 1.889 0.271 - 451.9 1 2 0 0.0083 12 0 0 0 5.06E+06 4.46E+06 - - - 2.7136 0.9573 221125_WJC_METTL3_EV_vs_WT_F05.11458.11458.3 0.435 Aug-40 K.DLVAQAPLKPK.T sp|O94776|MTA2_HUMAN 1 1178.7023 0.78 63640 11458 3 1178.701444 393.908 Metastasis-associated protein MTA2 OS=Homo sapiens OX=9606 GN=MTA2 PE=1 SV=1 8.59 2281.1 - 328165 - - - -0.7339 - 1.301 0.149 - 62.7 1 2 0 -0.0009 11 0 0 0 8.13E+06 1.05E+07 - - - 0.9485 1 221125_WJC_METTL3_EV_vs_WT_F05.11464.11464.2 3.09E-07 15/26 R.APSTYGGGLSVSSR.F sp|P08779|K1C16_HUMAN 1 1337.6575 999 63644 11464 2 1337.656932 669.836 "Keratin, type I cytoskeletal 16 OS=Homo sapiens OX=9606 GN=KRT16 PE=1 SV=4" 8.79 2281.7 - 2.11E+06 - - - -0.4568 - 2.593 0.586 - 670.2 1 2 0 -0.0006 14 0 0 0 5.21E+09 0.00E+00 - - - 5.76 0.8398 221125_WJC_METTL3_EV_vs_WT_F05.11465.11465.2 0.235 16-Oct S.KIEISELNR.V "sp|P04264|K2C1_HUMAN,sp|P35908|K22E_HUMAN" 2 1100.619 45.39 63645 11465 2 1100.619163 551.3168 "Keratin, type II cytoskeletal 1 OS=Homo sapiens OX=9606 GN=KRT1 PE=1 SV=6" 6.14 2281.8 - 1.61E+06 - - - 0.1726 - 1.841 0.087 - 372.1 1 1 0 0.0002 9 0 0 0 1.72E+07 3.79E+05 - - - 1.4492 0.9999 221125_WJC_METTL3_EV_vs_WT_F05.11466.11466.2 1.68E-06 15/20 K.DLLHPSPEEEK[136.11].R sp|P42677|RS27_HUMAN 1 1300.639 0.74 63646 11466 2 1300.637151 651.3268 40S ribosomal protein S27 OS=Homo sapiens OX=9606 GN=RPS27 PE=1 SV=3 4.4 2281.9 - 1.31E+06 - - - -1.457 - 2.785 0.49 - 573.4 1 2 0 -0.0019 11 0 0 0 3.63E+07 4.90E+07 - - - 5.4304 0.9998 221125_WJC_METTL3_EV_vs_WT_F05.11467.11467.2 0.000171 14/24 R.SVSLTGAPESVQK[136.11].A "sp|Q92945|FUBP2_HUMAN,tr|M0R0I5|M0R0I5_HUMAN,tr|M0QYH3|M0QYH3_HUMAN,tr|M0R0C6|M0R0C6_HUMAN,tr|M0QXW7|M0QXW7_HUMAN,tr|A0A087WTP3|A0A087WTP3_HUMAN" 6 1309.6969 1.21 63647 11467 2 1309.696545 655.8557 Far upstream element-binding protein 2 OS=Homo sapiens OX=9606 GN=KHSRP PE=1 SV=4 5.72 2282 - 1.13E+06 - - - -0.268 - 2.451 0.417 - 638 1 2 0 -0.0003 13 0 0 0 2.00E+08 1.66E+08 - - - 4.4217 0.9997 221125_WJC_METTL3_EV_vs_WT_F05.11469.11469.2 0.00405 20-Nov R.YELPAPSSGQK[136.11].N sp|O75934|SPF27_HUMAN 1 1183.5965 1.49 63649 11469 2 1183.595502 592.8055 Pre-mRNA-splicing factor SPF27 OS=Homo sapiens OX=9606 GN=BCAS2 PE=1 SV=1 6 2282.3 - 656822 - - - -0.8035 - 1.781 0.401 - 388.2 1 2 0 -0.001 11 0 0 0 3.42E+07 2.30E+07 - - - 3.5639 0.9998 221125_WJC_METTL3_EV_vs_WT_F05.11471.11471.2 2.11E-05 22-Oct K.GSFSDTGLGDGK[136.11].M "sp|Q9Y2W1|TR150_HUMAN,tr|A0A3B3ITZ9|A0A3B3ITZ9_HUMAN" 2 1147.5237 2.74 63651 11471 2 1147.524506 574.7691 Thyroid hormone receptor-associated protein 3 OS=Homo sapiens OX=9606 GN=THRAP3 PE=1 SV=2 4.21 2282.5 - 432345 - - - 0.7181 - 1.793 0.516 - 215.1 1 2 0 0.0008 12 0 0 0 8.80E+07 3.21E+07 - - - 4.3882 0.9999 221125_WJC_METTL3_EV_vs_WT_F05.11477.11477.3 0.000891 Sep-44 R.TAAENDFVTLKK.D sp|P35908|K22E_HUMAN 1 1335.7034 3253.55 63655 11477 3 1335.701347 446.2418 "Keratin, type II cytoskeletal 2 epidermal OS=Homo sapiens OX=9606 GN=KRT2 PE=1 SV=2" 5.73 2283.2 - 2.53E+06 - - - -1.5602 - 1.932 0.43 - 110.9 1 2 0 -0.0021 12 0 0 0 3.42E+09 1.05E+06 - - - 5.1589 0.9997 221125_WJC_METTL3_EV_vs_WT_F05.11478.11478.2 1.48E-08 13/22 K.AQNTWGC[160.03]GNSLR.T "sp|P02545|LMNA_HUMAN,tr|A0A804HL68|A0A804HL68_HUMAN,tr|Q5TCI8|Q5TCI8_HUMAN,tr|A0A6Q8PFJ0|A0A6Q8PFJ0_HUMAN" 4 1362.6099 2.16 63656 11478 2 1362.607786 682.3122 Prelamin-A\C OS=Homo sapiens OX=9606 GN=LMNA PE=1 SV=1 8.29 2283.3 - 1.11E+06 - - - -1.5382 - 2.542 0.338 - 635.2 1 2 0 -0.0021 12 0 0 0 1.08E+07 4.99E+06 - - - 3.9916 0.9789 221125_WJC_METTL3_EV_vs_WT_F05.11481.11481.2 8.96E-05 16-Aug L.LHPSPEEEK.R sp|P42677|RS27_HUMAN 1 1064.5138 1.01 63659 11481 2 1064.51258 533.2642 40S ribosomal protein S27 OS=Homo sapiens OX=9606 GN=RPS27 PE=1 SV=3 4.75 2283.7 - 555406 - - - -1.1827 - 1.526 0.462 - 227.8 1 1 0 -0.0013 9 0 0 0 1.51E+07 1.49E+07 - - - 3.6757 0.9987 221125_WJC_METTL3_EV_vs_WT_F05.11486.11486.2 1.45E-05 24-Nov R.SVSLTGAPESVQK.A "sp|Q92945|FUBP2_HUMAN,tr|M0R0I5|M0R0I5_HUMAN,tr|M0QYH3|M0QYH3_HUMAN,tr|M0R0C6|M0R0C6_HUMAN,tr|M0QXW7|M0QXW7_HUMAN,tr|A0A087WTP3|A0A087WTP3_HUMAN" 6 1301.6827 1.21 63662 11486 2 1301.687965 651.8486 Far upstream element-binding protein 2 OS=Homo sapiens OX=9606 GN=KHSRP PE=1 SV=4 5.72 2284.2 - 3.76E+06 - - - 4.0478 - 2.165 0.496 - 338 1 2 0 0.0053 13 0 0 0 2.00E+08 1.66E+08 - - - 4.6852 0.9996 221125_WJC_METTL3_EV_vs_WT_F05.11488.11488.3 0.000728 13/44 K.LK[136.11]DPPQGYFGPK[136.11].L sp|Q9UKJ3|GPTC8_HUMAN 1 1361.7314 1.64 63664 11488 3 1361.729877 454.9178 G patch domain-containing protein 8 OS=Homo sapiens OX=9606 GN=GPATCH8 PE=1 SV=2 8.5 2284.4 - 716102 - - - -1.1456 - 2.727 0.367 - 243.5 1 2 1 -0.0016 12 0 0 0 2.87E+07 1.75E+07 - - - 5.412 0.9997 221125_WJC_METTL3_EV_vs_WT_F05.11493.11493.3 0.00833 Dec-40 R.SSLLIEQPVKK.R "sp|Q8NDX5|PHC3_HUMAN,tr|E7EX82|E7EX82_HUMAN" 2 1240.7391 2.54 63669 11493 3 1240.737213 414.587 Polyhomeotic-like protein 3 OS=Homo sapiens OX=9606 GN=PHC3 PE=1 SV=1 8.31 2285.1 - 365214 - - - -1.5112 - 1.991 0.361 - 131.5 1 2 0 -0.0019 11 0 0 0 8.75E+06 3.45E+06 - - - 4.5206 0.9123 221125_WJC_METTL3_EV_vs_WT_F05.11496.11496.2 0.00912 16-Aug L.LHPSPEEEK[136.11].R sp|P42677|RS27_HUMAN 1 1072.528 1.01 63670 11496 2 1072.525973 537.2713 40S ribosomal protein S27 OS=Homo sapiens OX=9606 GN=RPS27 PE=1 SV=3 4.75 2285.4 - 916394 - - - -1.9263 - 1.402 0.349 - 240.9 1 1 0 -0.0021 9 0 0 0 1.51E+07 1.49E+07 - - - 2.5956 0.9998 221125_WJC_METTL3_EV_vs_WT_F05.11497.11497.2 4.13E-05 20-Nov R.TEEGPTLSYGR[166.11].D "sp|P43243|MATR3_HUMAN,tr|A8MXP9|A8MXP9_HUMAN,tr|D6R991|D6R991_HUMAN,tr|A0A0R4J2E8|A0A0R4J2E8_HUMAN,tr|D6REM6|D6REM6_HUMAN" 5 1218.5756 1.38 63671 11497 2 1218.575156 610.2951 Matrin-3 OS=Homo sapiens OX=9606 GN=MATR3 PE=1 SV=2 4.53 2285.6 - 1.03E+06 - - - -0.3652 - 2.17 0.43 - 505 1 2 0 -0.0004 11 0 0 0 2.96E+08 2.14E+08 - - - 4.3127 0.9999 221125_WJC_METTL3_EV_vs_WT_F05.11498.11498.3 0.000602 14/40 R.ILRPWQSSETR.S "sp|Q15637|SF01_HUMAN,tr|A0A7P0T9U7|A0A7P0T9U7_HUMAN" 2 1371.7259 1.04 63672 11498 3 1371.724496 458.2492 Splicing factor 1 OS=Homo sapiens OX=9606 GN=SF1 PE=1 SV=4 9.6 2285.7 - 1.31E+06 - - - -1.0221 - 2.56 0.412 - 350.4 1 2 0 -0.0014 11 0 0 0 1.04E+08 9.96E+07 - - - 5.8034 0.9996 221125_WJC_METTL3_EV_vs_WT_F05.11499.11499.3 0.0657 Dec-40 R.LNSK[136.11]PPNIGFK[136.11].K sp|Q9Y295|DRG1_HUMAN 1 1229.7103 0.43 63673 11499 3 1229.709314 410.9107 Developmentally-regulated GTP-binding protein 1 OS=Homo sapiens OX=9606 GN=DRG1 PE=1 SV=1 10 2285.8 - 1.03E+06 - - - -0.8083 - 2.065 0.312 - 114.7 1 2 0 -0.001 11 0 0 0 2.35E+07 5.52E+07 - - - 4.0782 1 221125_WJC_METTL3_EV_vs_WT_F05.11500.11500.3 4.59E-07 18/52 K.ISHVVVEDTVVSDK[136.11].C sp|Q7Z5K2|WAPL_HUMAN 1 1533.813 0.33 63674 11500 3 1533.813698 512.2783 Wings apart-like protein homolog OS=Homo sapiens OX=9606 GN=WAPL PE=1 SV=1 4.54 2286 - 848983 - - - 0.4629 - 3.251 0.539 - 583.9 1 2 0 0.0007 14 0 0 0 3.69E+06 1.11E+07 - - - 7.6823 0.939 221125_WJC_METTL3_EV_vs_WT_F05.11502.11502.2 5.71E-06 18-Nov A.AENDFVTLKK.D sp|P35908|K22E_HUMAN 1 1163.6186 999 63676 11502 2 1163.623765 582.8166 "Keratin, type II cytoskeletal 2 epidermal OS=Homo sapiens OX=9606 GN=KRT2 PE=1 SV=2" 6.11 2286.2 - 481031 - - - 4.4052 - 2.237 0.59 - 476.4 1 1 0 0.0051 10 0 0 0 9.05E+07 0.00E+00 - - - 5.6445 0.9972 221125_WJC_METTL3_EV_vs_WT_F05.11505.11505.2 0.124 16-Jul R.KQLFAC[160.03]VPK.T "sp|Q8IWZ3|ANKH1_HUMAN,tr|A0A0A0MQZ8|A0A0A0MQZ8_HUMAN,tr|H0Y472|H0Y472_HUMAN,tr|H0Y7Y3|H0Y7Y3_HUMAN,tr|H0Y4P6|H0Y4P6_HUMAN,tr|H0Y785|H0Y785_HUMAN" 6 1089.6005 1.08 63679 11505 2 1089.599677 545.8075 Ankyrin repeat and KH domain-containing protein 1 OS=Homo sapiens OX=9606 GN=ANKHD1 PE=1 SV=1 9.31 2286.6 - 428854 - - - -0.7425 - 1.472 0.195 - 154.3 1 2 0 -0.0008 9 0 0 0 6.74E+06 6.26E+06 - - - 1.5995 0.9999 221125_WJC_METTL3_EV_vs_WT_F05.11508.11508.2 8.61E-05 20-Nov K.EAANELQSIQR.L sp|Q13207|TBX2_HUMAN 1 1257.6313 0.35 63681 11508 2 1257.630698 629.8229 T-box transcription factor TBX2 OS=Homo sapiens OX=9606 GN=TBX2 PE=1 SV=3 4.53 2287 - 1.95E+06 - - - -0.5017 - 2.621 0.517 - 618.9 1 2 0 -0.0006 11 0 0 0 2.42E+07 6.98E+07 - - - 5.466 0.9998 221125_WJC_METTL3_EV_vs_WT_F05.11510.11510.2 0.0107 20-Sep R.TEEGPTLSYGR.D "sp|P43243|MATR3_HUMAN,tr|A8MXP9|A8MXP9_HUMAN,tr|D6R991|D6R991_HUMAN,tr|A0A0R4J2E8|A0A0R4J2E8_HUMAN,tr|D6REM6|D6REM6_HUMAN" 5 1208.5673 1.38 63682 11510 2 1208.566697 605.2909 Matrin-3 OS=Homo sapiens OX=9606 GN=MATR3 PE=1 SV=2 4.53 2287.2 - 3.01E+06 - - - -0.5246 - 2.135 0.453 - 290.3 1 2 0 -0.0006 11 0 0 0 2.96E+08 2.14E+08 - - - 4.4385 0.9999 221125_WJC_METTL3_EV_vs_WT_F05.11511.11511.2 3.74E-06 16-Oct K.DVNQQEFVR.A "sp|P39019|RS19_HUMAN,tr|M0R140|M0R140_HUMAN,tr|M0R2L9|M0R2L9_HUMAN,tr|M0QYF7|M0QYF7_HUMAN" 4 1133.5465 1.16 63683 11511 2 1133.546494 567.7805 40S ribosomal protein S19 OS=Homo sapiens OX=9606 GN=RPS19 PE=1 SV=2 4.37 2287.3 - 940859 - - - -0.0371 - 2.096 0.521 - 377.9 1 2 0 0 9 0 0 0 1.29E+08 1.11E+08 - - - 5.03 1 221125_WJC_METTL3_EV_vs_WT_F05.11513.11513.2 1.23E-07 20-Nov R.SSGC[160.03]FPNMAAK.V sp|Q96I24|FUBP3_HUMAN 1 1168.5005 1.71 63685 11513 2 1168.499013 585.2575 Far upstream element-binding protein 3 OS=Homo sapiens OX=9606 GN=FUBP3 PE=1 SV=2 7.94 2287.5 - 996679 - - - -1.2846 - 2.05 0.653 - 416.4 1 2 0 -0.0015 11 0 0 0 1.21E+08 7.07E+07 - - - 5.8055 0.9999 221125_WJC_METTL3_EV_vs_WT_F05.11514.11514.3 0.000816 14/44 R.VNVPVIGGHAGK.T "sp|P40926|MDHM_HUMAN,tr|G3XAL0|G3XAL0_HUMAN" 2 1146.6509 0.99 63686 11514 3 1146.649926 383.2243 "Malate dehydrogenase, mitochondrial OS=Homo sapiens OX=9606 GN=MDH2 PE=1 SV=3" 8.73 2287.6 - 590943 - - - -0.8861 - 2.409 0.424 - 224.9 1 2 0 -0.001 12 0 0 0 3.56E+07 3.62E+07 - - - 5.7039 0.9995 221125_WJC_METTL3_EV_vs_WT_F05.11517.11517.3 0.000318 Nov-48 K.NLVPGESVYGEK[136.11]R[166.11].V "sp|P22087|FBRL_HUMAN,tr|M0R299|M0R299_HUMAN,tr|M0R0P1|M0R0P1_HUMAN,tr|M0R1H0|M0R1H0_HUMAN,tr|M0QXL5|M0QXL5_HUMAN,tr|M0R2Q4|M0R2Q4_HUMAN,tr|M0R2B0|M0R2B0_HUMAN,tr|M0R2U2|M0R2U2_HUMAN" 8 1464.7692 0.89 63687 11517 3 1464.763214 489.2637 rRNA 2'-O-methyltransferase fibrillarin OS=Homo sapiens OX=9606 GN=FBL PE=1 SV=2 6.14 2288 - 2.51E+06 - - - -4.0614 - 2.325 0.429 - 194.1 1 2 0 -0.0059 13 0 0 0 6.87E+07 7.75E+07 - - - 5.6088 1 221125_WJC_METTL3_EV_vs_WT_F05.11518.11518.2 8.66E-08 14/30 T.NEEAGDGTTTATVLAR.S "sp|P10809|CH60_HUMAN,tr|C9JL25|C9JL25_HUMAN,tr|A0A7I2V2X6|A0A7I2V2X6_HUMAN,tr|A0A7I2YQK6|A0A7I2YQK6_HUMAN,tr|A0A7I2V599|A0A7I2V599_HUMAN,tr|E7EXB4|E7EXB4_HUMAN,tr|A0A7I2YQ71|A0A7I2YQ71_HUMAN,tr|E7ESH4|E7ESH4_HUMAN,tr|A0A7I2V5M1|A0A7I2V5M1_HUMAN,tr|A0A7I2V5K3|A0A7I2V5K3_HUMAN,tr|A0A7I2V369|A0A7I2V369_HUMAN" 11 1604.7642 1.35 63688 11518 2 1604.760436 803.3894 "60 kDa heat shock protein, mitochondrial OS=Homo sapiens OX=9606 GN=HSPD1 PE=1 SV=2" 4.14 2288.1 - 477404 - - - -2.3412 - 2.826 0.616 - 559.9 1 1 0 -0.0038 16 0 0 0 8.52E+06 6.32E+06 - - - 6.1437 1 221125_WJC_METTL3_EV_vs_WT_F05.11519.11519.3 9.12E-06 15/52 R.VLQSHISDTSVVVK.M "sp|A6NCN2|KR87P_HUMAN,sp|O43790|KRT86_HUMAN" 2 1510.8355 999 63689 11519 3 1510.834854 504.6191 Putative keratin-87 protein OS=Homo sapiens OX=9606 GN=KRT87P PE=5 SV=4 6.71 2288.3 - 1.03E+06 - - - -0.4329 - 2.715 0.445 - 229 1 2 0 -0.0007 14 0 0 0 1.25E+07 0.00E+00 - - - 6.1555 1 221125_WJC_METTL3_EV_vs_WT_F05.11520.11520.2 8.31E-06 14/24 K.QGIETPEDQNDLR[166.11].K "sp|Q15637|SF01_HUMAN,tr|A0A7P0T9U7|A0A7P0T9U7_HUMAN" 2 1523.7091 1.28 63690 11520 2 1523.706948 762.8618 Splicing factor 1 OS=Homo sapiens OX=9606 GN=SF1 PE=1 SV=4 3.92 2288.4 - 683035 - - - -1.4353 - 2.827 0.577 - 267.5 1 2 0 -0.0022 13 0 0 0 4.02E+07 3.15E+07 - - - 5.9692 0.8262 221125_WJC_METTL3_EV_vs_WT_F05.11521.11521.2 8.01E-07 13/30 T.NEEAGDGTTTATVLAR[166.11].S "sp|P10809|CH60_HUMAN,tr|C9JL25|C9JL25_HUMAN,tr|A0A7I2V2X6|A0A7I2V2X6_HUMAN,tr|A0A7I2YQK6|A0A7I2YQK6_HUMAN,tr|A0A7I2V599|A0A7I2V599_HUMAN,tr|E7EXB4|E7EXB4_HUMAN,tr|A0A7I2YQ71|A0A7I2YQ71_HUMAN,tr|E7ESH4|E7ESH4_HUMAN,tr|A0A7I2V5M1|A0A7I2V5M1_HUMAN,tr|A0A7I2V5K3|A0A7I2V5K3_HUMAN,tr|A0A7I2V369|A0A7I2V369_HUMAN" 11 1614.7725 1.45 63691 11521 2 1614.766962 808.3935 "60 kDa heat shock protein, mitochondrial OS=Homo sapiens OX=9606 GN=HSPD1 PE=1 SV=2" 4.14 2288.5 - 650105 - - - -3.4067 - 2.772 0.18 - 563 1 1 0 -0.0055 16 0 0 0 8.43E+06 5.79E+06 - - - 2.8754 0.9999 221125_WJC_METTL3_EV_vs_WT_F05.11522.11522.3 0.00034 15/36 R.LSEGFSIHTR[166.11].D sp|P20618|PSB1_HUMAN 1 1155.5912 1.08 63692 11522 3 1155.588899 386.2043 Proteasome subunit beta type-1 OS=Homo sapiens OX=9606 GN=PSMB1 PE=1 SV=2 6.75 2288.7 - 638961 - - - -1.9843 - 2.48 0.452 - 278.9 1 2 0 -0.0023 10 0 0 0 2.69E+07 2.50E+07 - - - 6.2312 0.9998 221125_WJC_METTL3_EV_vs_WT_F05.11525.11525.2 6.24E-06 16-Sep K.DVNQQEFVR[166.11].A "sp|P39019|RS19_HUMAN,tr|M0R140|M0R140_HUMAN,tr|M0R2L9|M0R2L9_HUMAN,tr|M0QYF7|M0QYF7_HUMAN" 4 1143.5548 1.18 63693 11525 2 1143.552937 572.7847 40S ribosomal protein S19 OS=Homo sapiens OX=9606 GN=RPS19 PE=1 SV=2 4.37 2289 - 2.95E+06 - - - -1.6344 - 1.997 0.559 - 316.4 1 2 0 -0.0019 9 0 0 0 1.29E+08 1.09E+08 - - - 5.1702 0.9998 221125_WJC_METTL3_EV_vs_WT_F05.11527.11527.3 2.45E-05 Dec-48 K.NLVPGESVYGEKR.V "sp|P22087|FBRL_HUMAN,tr|M0R299|M0R299_HUMAN,tr|M0R0P1|M0R0P1_HUMAN,tr|M0R1H0|M0R1H0_HUMAN,tr|M0QXL5|M0QXL5_HUMAN,tr|M0R2Q4|M0R2Q4_HUMAN,tr|M0R2B0|M0R2B0_HUMAN,tr|M0R2U2|M0R2U2_HUMAN" 8 1446.7467 0.89 63695 11527 3 1446.741688 483.2562 rRNA 2'-O-methyltransferase fibrillarin OS=Homo sapiens OX=9606 GN=FBL PE=1 SV=2 6.14 2289.2 - 2.59E+06 - - - -3.4595 - 2.249 0.469 - 195.2 1 2 0 -0.005 13 0 0 0 6.87E+07 7.75E+07 - - - 5.965 1 221125_WJC_METTL3_EV_vs_WT_F05.11528.11528.2 9.55E-07 15/24 K.QGIETPEDQNDLR.K "sp|Q15637|SF01_HUMAN,tr|A0A7P0T9U7|A0A7P0T9U7_HUMAN" 2 1513.7009 1.27 63696 11528 2 1513.698799 757.8577 Splicing factor 1 OS=Homo sapiens OX=9606 GN=SF1 PE=1 SV=4 3.92 2289.3 - 1.36E+06 - - - -1.3649 - 2.982 0.599 - 727.6 1 2 0 -0.0021 13 0 0 0 4.02E+07 3.17E+07 - - - 6.2687 0.9991 221125_WJC_METTL3_EV_vs_WT_F05.11529.11529.2 0.00159 20-Sep R.YELPAPSSGQK.N sp|O75934|SPF27_HUMAN 1 1175.5823 1.46 63697 11529 2 1175.582515 588.7984 Pre-mRNA-splicing factor SPF27 OS=Homo sapiens OX=9606 GN=BCAS2 PE=1 SV=1 6 2289.4 - 1.29E+06 - - - 0.2229 - 1.405 0.343 - 135.6 1 2 0 0.0003 11 0 0 0 3.57E+07 2.45E+07 - - - 2.4942 0.9994 221125_WJC_METTL3_EV_vs_WT_F05.11532.11532.3 0.000156 Dec-44 K.LKDPPQGYFGPK.L sp|Q9UKJ3|GPTC8_HUMAN 1 1345.703 0.95 63700 11532 3 1345.700664 449.575 G patch domain-containing protein 8 OS=Homo sapiens OX=9606 GN=GPATCH8 PE=1 SV=2 8.5 2289.7 - 863942 - - - -1.7634 - 2.349 0.402 - 206.8 1 2 1 -0.0024 12 0 0 0 1.44E+07 1.52E+07 - - - 5.3884 0.9996 221125_WJC_METTL3_EV_vs_WT_F05.11533.11533.3 0.00224 Dec-36 R.LSEGFSIHTR.D sp|P20618|PSB1_HUMAN 1 1145.5829 1.08 63701 11533 3 1145.581011 382.8683 Proteasome subunit beta type-1 OS=Homo sapiens OX=9606 GN=PSMB1 PE=1 SV=2 6.75 2289.9 - 803661 - - - -1.6681 - 2.075 0.326 - 158.7 1 2 0 -0.0019 10 0 0 0 2.71E+07 2.50E+07 - - - 4.3059 1 221125_WJC_METTL3_EV_vs_WT_F05.11534.11534.2 3.09E-07 13/24 K.QMENTALQNEVQR[166.11].L "sp|Q15643|TRIPB_HUMAN,tr|H0YJ97|H0YJ97_HUMAN" 2 1569.7445 2.67 63702 11534 2 1569.746663 785.8795 Thyroid receptor-interacting protein 11 OS=Homo sapiens OX=9606 GN=TRIP11 PE=1 SV=3 4.53 2290 - 602265 - - - 1.3945 - 2.939 0.604 - 794.7 1 2 0 0.0022 13 0 0 0 4.75E+07 1.78E+07 - - - 6.2684 0.9999 221125_WJC_METTL3_EV_vs_WT_F05.11536.11536.3 7.10E-06 13/48 K.QMENTALQNEVQR[166.11].L "sp|Q15643|TRIPB_HUMAN,tr|H0YJ97|H0YJ97_HUMAN" 2 1569.7445 1.71 63704 11536 3 1569.742307 524.2554 Thyroid receptor-interacting protein 11 OS=Homo sapiens OX=9606 GN=TRIP11 PE=1 SV=3 4.53 2290.2 - 508233 - - - -1.3805 - 2.495 0.382 - 339 1 2 0 -0.0022 13 0 0 0 1.37E+07 7.99E+06 - - - 5.2772 1 221125_WJC_METTL3_EV_vs_WT_F05.11537.11537.2 1.29E-06 13/32 R.SGAVQGAGSLGPGSPVR.A sp|Q9P270|SLAI2_HUMAN 1 1495.7743 1.57 63705 11537 2 1495.77008 748.8944 SLAIN motif-containing protein 2 OS=Homo sapiens OX=9606 GN=SLAIN2 PE=1 SV=2 9.47 2290.4 - 431749 - - - -2.8246 - 2.783 0.603 - 472.5 1 2 0 -0.0042 17 0 0 0 1.26E+07 8.03E+06 - - - 6.0098 0.999 221125_WJC_METTL3_EV_vs_WT_F05.11540.11540.2 4.21E-05 20-Oct R.SSGC[160.03]FPNMAAK[136.11].V sp|Q96I24|FUBP3_HUMAN 1 1176.5147 1.71 63706 11540 2 1176.511283 589.2646 Far upstream element-binding protein 3 OS=Homo sapiens OX=9606 GN=FUBP3 PE=1 SV=2 7.94 2290.8 - 1.56E+06 - - - -2.9162 - 1.595 0.476 - 228.6 1 2 0 -0.0034 11 0 0 0 1.21E+08 7.07E+07 - - - 3.8187 0.9997 221125_WJC_METTL3_EV_vs_WT_F05.11542.11542.2 1.14E-05 22-Nov R.SGYGFNEPEQSR.F sp|Q5BKZ1|ZN326_HUMAN 1 1369.5899 1.39 63708 11542 2 1369.592715 685.8022 DBIRD complex subunit ZNF326 OS=Homo sapiens OX=9606 GN=ZNF326 PE=1 SV=2 4.53 2291 - 847693 - - - 2.086 - 1.913 0.523 - 335.1 1 2 0 0.0029 12 0 0 0 2.40E+07 1.72E+07 - - - 4.6097 0.9997 221125_WJC_METTL3_EV_vs_WT_F05.11544.11544.2 0.000205 18-Oct R.GC[160.03]VQDEFC[160.03]TR.D sp|O95274|LYPD3_HUMAN 1 1270.5071 999 63710 11544 2 1270.503535 636.2608 Ly6\PLAUR domain-containing protein 3 OS=Homo sapiens OX=9606 GN=LYPD3 PE=1 SV=2 4.37 2291.3 - 646027 - - - -2.7721 - 1.878 0.628 - 463.4 1 2 0 -0.0035 10 0 0 0 9.86E+06 0.00E+00 - - - 5.4374 1 221125_WJC_METTL3_EV_vs_WT_F05.11546.11546.2 4.57E-07 15/32 R.SGAVQGAGSLGPGSPVR[166.11].A sp|Q9P270|SLAI2_HUMAN 1 1505.7826 1.57 63712 11546 2 1505.783822 753.8986 SLAIN motif-containing protein 2 OS=Homo sapiens OX=9606 GN=SLAIN2 PE=1 SV=2 9.47 2291.6 - 565987 - - - 0.8281 - 2.85 0.617 - 692.4 1 2 0 0.0012 17 0 0 0 1.26E+07 8.03E+06 - - - 6.1727 0.9998 221125_WJC_METTL3_EV_vs_WT_F05.11551.11551.3 0.00117 Nov-32 R.K[136.11]LTVEDFNR[166.11].A "sp|Q9Y6J9|TAF6L_HUMAN,tr|E9PP94|E9PP94_HUMAN" 2 1138.6101 0.001 63715 11551 3 1138.608609 380.544 TAF6-like RNA polymerase II p300\CBP-associated factor-associated factor 65 kDa subunit 6L OS=Homo sapiens OX=9606 GN=TAF6L PE=1 SV=1 6.07 2292.2 - 694652 - - - -1.3473 - 2.043 0.36 - 222.4 1 2 0 -0.0015 9 0 0 0 0.00E+00 6.57E+06 - - - 4.7063 0.9986 221125_WJC_METTL3_EV_vs_WT_F05.11553.11553.3 0.00963 Sep-48 K.QMENTALQNEVQR.L "sp|Q15643|TRIPB_HUMAN,tr|H0YJ97|H0YJ97_HUMAN" 2 1559.7362 1.76 63717 11553 3 1559.738475 520.9193 Thyroid receptor-interacting protein 11 OS=Homo sapiens OX=9606 GN=TRIP11 PE=1 SV=3 4.53 2292.4 - 746359 - - - 1.456 - 1.845 0.279 - 155.3 1 2 0 0.0023 13 0 0 0 1.41E+07 7.99E+06 - - - 3.3106 0.9904 221125_WJC_METTL3_EV_vs_WT_F05.11554.11554.2 0.00641 13/22 F.SSGSAGIINYQR.R sp|P04264|K2C1_HUMAN 1 1251.6208 28.52 63718 11554 2 1251.621251 626.8177 "Keratin, type II cytoskeletal 1 OS=Homo sapiens OX=9606 GN=KRT1 PE=1 SV=6" 8.46 2292.5 - 419512 - - - 0.3891 - 2.358 0.431 - 638.6 1 1 0 0.0005 12 0 0 0 5.79E+06 2.03E+05 - - - 4.4813 0.8102 221125_WJC_METTL3_EV_vs_WT_F05.11555.11555.2 0.599 16-Jun K.EKGTWVQLK.R sp|P46778|RL21_HUMAN 1 1087.6026 0.71 63719 11555 2 1087.600454 544.8086 60S ribosomal protein L21 OS=Homo sapiens OX=9606 GN=RPL21 PE=1 SV=2 8.69 2292.7 - 411328 - - - -1.9685 - 1.368 0.14 - 81.1 6 2 1 -0.0021 9 0 0 0 7.17E+06 1.01E+07 - - - 0.6333 0.9995 221125_WJC_METTL3_EV_vs_WT_F05.11556.11556.2 0.000815 24-Oct K.NLVPGESVYGEKR.V "sp|P22087|FBRL_HUMAN,tr|M0R299|M0R299_HUMAN,tr|M0R0P1|M0R0P1_HUMAN,tr|M0R1H0|M0R1H0_HUMAN,tr|M0QXL5|M0QXL5_HUMAN,tr|M0R2Q4|M0R2Q4_HUMAN,tr|M0R2B0|M0R2B0_HUMAN,tr|M0R2U2|M0R2U2_HUMAN" 8 1446.7467 0.8 63720 11556 2 1446.743474 724.3806 rRNA 2'-O-methyltransferase fibrillarin OS=Homo sapiens OX=9606 GN=FBL PE=1 SV=2 6.14 2292.8 - 380186 - - - -2.225 - 1.961 0.466 - 246.1 1 2 0 -0.0032 13 0 0 0 4.48E+06 5.60E+06 - - - 4.2103 0.9433 221125_WJC_METTL3_EV_vs_WT_F05.11559.11559.2 5.50E-05 20-Dec K.SNFVPTNVGSK.A "sp|P10092|CALCB_HUMAN,tr|E7ESF5|E7ESF5_HUMAN" 2 1148.5826 0.76 63721 11559 2 1148.589795 575.2986 Calcitonin gene-related peptide 2 OS=Homo sapiens OX=9606 GN=CALCB PE=1 SV=1 8.47 2293.2 - 968902 - - - 6.2747 - 1.889 0.188 - 332.8 1 2 0 0.0072 11 0 0 0 1.19E+07 1.57E+07 - - - 2.148 0.9987 221125_WJC_METTL3_EV_vs_WT_F05.11560.11560.3 0.0379 Dec-40 K.IHPTSVISGYR[166.11].L "sp|P17987|TCPA_HUMAN,tr|F5H136|F5H136_HUMAN,tr|E7ERF2|E7ERF2_HUMAN,tr|F5H676|F5H676_HUMAN" 4 1238.6647 0.36 63722 11560 3 1238.665836 413.8955 T-complex protein 1 subunit alpha OS=Homo sapiens OX=9606 GN=TCP1 PE=1 SV=1 8.75 2293.3 - 932370 - - - 0.9244 - 1.892 0.252 - 181.8 1 2 0 0.0011 11 0 0 0 8.09E+06 2.26E+07 - - - 3.1606 0.9999 221125_WJC_METTL3_EV_vs_WT_F05.11561.11561.3 2.68E-05 14/44 R.YLAEFATGNDR[166.11]K[136.11].E "sp|P62258|1433E_HUMAN,tr|K7EM20|K7EM20_HUMAN" 2 1401.7007 1.03 63723 11561 3 1401.698773 468.2409 14-3-3 protein epsilon OS=Homo sapiens OX=9606 GN=YWHAE PE=1 SV=1 6.07 2293.4 - 1.83E+06 - - - -1.4097 - 2.42 0.438 - 176.9 1 2 0 -0.002 12 0 0 0 1.26E+08 1.22E+08 - - - 5.8724 0.9999 221125_WJC_METTL3_EV_vs_WT_F05.11562.11562.3 0.00154 16/44 R.YLAEFATGNDRK.E "sp|P62258|1433E_HUMAN,tr|K7EM20|K7EM20_HUMAN" 2 1383.6783 1.03 63724 11562 3 1383.677652 462.2334 14-3-3 protein epsilon OS=Homo sapiens OX=9606 GN=YWHAE PE=1 SV=1 6.07 2293.5 - 1.48E+06 - - - -0.4531 - 2.695 0.404 - 222.9 1 2 0 -0.0006 12 0 0 0 1.26E+08 1.22E+08 - - - 5.792 0.9999 221125_WJC_METTL3_EV_vs_WT_F05.11563.11563.2 0.00951 13/22 K.NASDMPETITSR.D "sp|Q8TCT9|HM13_HUMAN,tr|A0A3B3IT72|A0A3B3IT72_HUMAN,tr|A0A0S2Z6F0|A0A0S2Z6F0_HUMAN,tr|A0A3B3IUB5|A0A3B3IUB5_HUMAN,tr|A0A0C4DGU3|A0A0C4DGU3_HUMAN,tr|A0A075B6F6|A0A075B6F6_HUMAN" 6 1320.598 1.28 63725 11563 2 1320.597709 661.3063 Minor histocompatibility antigen H13 OS=Homo sapiens OX=9606 GN=HM13 PE=1 SV=1 4.37 2293.6 - 1.33E+06 - - - -0.2052 - 2.326 0.574 - 599.7 1 2 0 -0.0003 12 0 0 0 2.42E+07 1.90E+07 - - - 5.5016 1 221125_WJC_METTL3_EV_vs_WT_F05.11564.11564.2 8.93E-09 30-Dec K.VATLNSEEESDPPTYK.D "sp|Q00341|VIGLN_HUMAN,tr|C9JHZ8|C9JHZ8_HUMAN,tr|C9JQ82|C9JQ82_HUMAN,tr|C9JMQ6|C9JMQ6_HUMAN,tr|C9JHN6|C9JHN6_HUMAN,tr|C9JZI8|C9JZI8_HUMAN,tr|C9JT62|C9JT62_HUMAN,tr|A0A024R4E5|A0A024R4E5_HUMAN,tr|C9JEJ8|C9JEJ8_HUMAN,tr|C9JIZ1|C9JIZ1_HUMAN,tr|C9JBS3|C9JBS3_HUMAN,tr|C9JES8|C9JES8_HUMAN,tr|C9J5E5|C9J5E5_HUMAN,tr|C9JK79|C9JK79_HUMAN,tr|C9JHS7|C9JHS7_HUMAN" 15 1778.821 1.7 63726 11564 2 1778.818688 890.4178 Vigilin OS=Homo sapiens OX=9606 GN=HDLBP PE=1 SV=2 4 2293.8 - 141655 - - - -1.3222 - 2.834 0.69 - 228.5 1 2 0 -0.0024 16 0 0 0 1.94E+07 1.14E+07 - - - 6.6976 1 221125_WJC_METTL3_EV_vs_WT_F05.11567.11567.2 4.64E-07 15/24 Q.SSAVGSAFTQDTR.S "sp|Q8ND56|LS14A_HUMAN,tr|A0A140TA76|A0A140TA76_HUMAN,tr|K7EMZ9|K7EMZ9_HUMAN" 3 1325.6212 1.26 63727 11567 2 1325.62 663.8179 Protein LSM14 homolog A OS=Homo sapiens OX=9606 GN=LSM14A PE=1 SV=3 5.55 2294.2 - 2.36E+06 - - - -0.8736 - 2.731 0.571 - 811 1 1 0 -0.0012 13 0 0 0 3.13E+07 2.48E+07 - - - 5.8366 0.9791 221125_WJC_METTL3_EV_vs_WT_F05.11569.11569.3 0.000589 Sep-32 K.DNDFIYHDR[166.11].V sp|Q8WUM4|PDC6I_HUMAN 1 1203.5184 0.3 63729 11569 3 1203.517868 402.1801 Programmed cell death 6-interacting protein OS=Homo sapiens OX=9606 GN=PDCD6IP PE=1 SV=1 4.41 2294.4 - 622025 - - - -0.4595 - 1.477 0.148 - 111.4 1 2 0 -0.0006 9 0 0 0 4.27E+06 1.42E+07 - - - 1.3653 0.9999 221125_WJC_METTL3_EV_vs_WT_F05.11573.11573.2 0.000247 22-Dec K.NASDMPETITSR[166.11].D "sp|Q8TCT9|HM13_HUMAN,tr|A0A3B3IT72|A0A3B3IT72_HUMAN,tr|A0A0S2Z6F0|A0A0S2Z6F0_HUMAN,tr|A0A3B3IUB5|A0A3B3IUB5_HUMAN,tr|A0A0C4DGU3|A0A0C4DGU3_HUMAN,tr|A0A075B6F6|A0A075B6F6_HUMAN" 6 1330.6063 1.28 63731 11573 2 1330.606407 666.3104 Minor histocompatibility antigen H13 OS=Homo sapiens OX=9606 GN=HM13 PE=1 SV=1 4.37 2294.9 - 1.41E+06 - - - 0.118 - 2.438 0.487 - 455.6 1 2 0 0.0002 12 0 0 0 2.42E+07 1.90E+07 - - - 4.9828 0.997 221125_WJC_METTL3_EV_vs_WT_F05.11575.11575.2 0.168 18-Oct R.TKYETELNLR.M sp|P02533|K1C14_HUMAN 1 1265.6616 15 63733 11575 2 1265.660603 633.8381 "Keratin, type I cytoskeletal 14 OS=Homo sapiens OX=9606 GN=KRT14 PE=1 SV=4" 5.81 2295.1 - 1.29E+06 - - - -0.7609 - 1.936 0.396 - 263 1 2 1 -0.001 10 0 0 0 1.63E+08 1.08E+07 - - - 3.8096 0.9876 221125_WJC_METTL3_EV_vs_WT_F05.11577.11577.2 0.0475 20-Jun K.IHPTSVISGYR[166.11].L "sp|P17987|TCPA_HUMAN,tr|F5H136|F5H136_HUMAN,tr|E7ERF2|E7ERF2_HUMAN,tr|F5H676|F5H676_HUMAN" 4 1238.6647 0.35 63735 11577 2 1238.662653 620.3396 T-complex protein 1 subunit alpha OS=Homo sapiens OX=9606 GN=TCP1 PE=1 SV=1 8.75 2295.4 - 503826 - - - -1.6453 - 1.143 0.194 - 102.5 1 2 0 -0.002 11 0 0 0 3.59E+06 1.02E+07 - - - 0.8348 0.9999 221125_WJC_METTL3_EV_vs_WT_F05.11578.11578.2 0.000734 22-Nov R.YLAEFATGNDR[166.11]K[136.11].E "sp|P62258|1433E_HUMAN,tr|K7EM20|K7EM20_HUMAN" 2 1401.7007 1.14 63736 11578 2 1401.701022 701.8577 14-3-3 protein epsilon OS=Homo sapiens OX=9606 GN=YWHAE PE=1 SV=1 6.07 2295.5 - 405954 - - - 0.1948 - 2.219 0.531 - 389.7 1 2 0 0.0003 12 0 0 0 1.25E+07 1.10E+07 - - - 5.0601 1 221125_WJC_METTL3_EV_vs_WT_F05.11581.11581.2 5.23E-09 Dec-34 L.YQGAGGPGPGGFGAQGPK[136.11].G "sp|P0DMV8|HS71A_HUMAN,sp|P0DMV9|HS71B_HUMAN,tr|V9GZ37|V9GZ37_HUMAN,tr|A0A0G2JIW1|A0A0G2JIW1_HUMAN" 4 1609.7729 0.13 63737 11581 2 1609.772529 805.8937 Heat shock 70 kDa protein 1A OS=Homo sapiens OX=9606 GN=HSPA1A PE=1 SV=1 8.59 2295.9 - 715654 - - - -0.2019 - 2.903 0.619 - 312.5 1 1 0 -0.0003 18 0 0 0 1.67E+06 1.27E+07 - - - 6.233 0.9966 221125_WJC_METTL3_EV_vs_WT_F05.11582.11582.3 0.000215 13/44 R.LTEKELAEAASK.W "sp|Q8NEY8|PPHLN_HUMAN,tr|B7Z8L1|B7Z8L1_HUMAN,tr|F8W6A0|F8W6A0_HUMAN,tr|F8W0Q9|F8W0Q9_HUMAN,tr|F8WF16|F8WF16_HUMAN" 5 1288.6874 1.59 63738 11582 3 1288.693797 430.5698 Periphilin-1 OS=Homo sapiens OX=9606 GN=PPHLN1 PE=1 SV=2 4.79 2296 - 820593 - - - 4.9275 - 2.499 0.438 - 227.9 1 2 1 0.0063 12 0 0 0 1.20E+07 7.57E+06 - - - 5.9602 1 221125_WJC_METTL3_EV_vs_WT_F05.11584.11584.2 1.89E-08 30-Dec K.VATLNSEEESDPPTYK[136.11].D "sp|Q00341|VIGLN_HUMAN,tr|C9JHZ8|C9JHZ8_HUMAN,tr|C9JQ82|C9JQ82_HUMAN,tr|C9JMQ6|C9JMQ6_HUMAN,tr|C9JHN6|C9JHN6_HUMAN,tr|C9JZI8|C9JZI8_HUMAN,tr|C9JT62|C9JT62_HUMAN,tr|A0A024R4E5|A0A024R4E5_HUMAN,tr|C9JEJ8|C9JEJ8_HUMAN,tr|C9JIZ1|C9JIZ1_HUMAN,tr|C9JBS3|C9JBS3_HUMAN,tr|C9JES8|C9JES8_HUMAN,tr|C9J5E5|C9J5E5_HUMAN,tr|C9JK79|C9JK79_HUMAN,tr|C9JHS7|C9JHS7_HUMAN" 15 1786.8352 1.7 63740 11584 2 1786.831539 894.4249 Vigilin OS=Homo sapiens OX=9606 GN=HDLBP PE=1 SV=2 4 2296.3 - 495995 - - - -2.0713 - 2.736 0.675 - 199.5 1 2 0 -0.0037 16 0 0 0 1.94E+07 1.14E+07 - - - 6.4999 0.9923 221125_WJC_METTL3_EV_vs_WT_F05.11589.11589.3 6.74E-08 13/68 L.YQGAGGPGPGGFGAQGPK[136.11].G "sp|P0DMV8|HS71A_HUMAN,sp|P0DMV9|HS71B_HUMAN,tr|V9GZ37|V9GZ37_HUMAN,tr|A0A0G2JIW1|A0A0G2JIW1_HUMAN" 4 1609.7729 0.14 63745 11589 3 1609.778318 537.5982 Heat shock 70 kDa protein 1A OS=Homo sapiens OX=9606 GN=HSPA1A PE=1 SV=1 8.59 2296.9 - 252618 - - - 3.3943 - 2.605 0.596 - 157 1 1 0 0.0055 18 0 0 0 5.30E+05 3.76E+06 - - - 7.5674 0.9998 221125_WJC_METTL3_EV_vs_WT_F05.11595.11595.3 0.00149 Nov-36 R.TKYETELNLR.M sp|P02533|K1C14_HUMAN 1 1265.6616 12.6 63749 11595 3 1265.66192 422.8945 "Keratin, type I cytoskeletal 14 OS=Homo sapiens OX=9606 GN=KRT14 PE=1 SV=4" 5.81 2297.6 - 4.90E+07 - - - 0.2797 - 2.454 0.445 - 298.4 1 2 1 0.0004 10 0 0 0 1.15E+09 9.16E+07 - - - 6.1229 0.9998 221125_WJC_METTL3_EV_vs_WT_F05.11597.11597.2 0.000413 22-Dec R.YLAEFATGNDRK.E "sp|P62258|1433E_HUMAN,tr|K7EM20|K7EM20_HUMAN" 2 1383.6783 1.15 63751 11597 2 1383.680425 692.8464 14-3-3 protein epsilon OS=Homo sapiens OX=9606 GN=YWHAE PE=1 SV=1 6.07 2297.8 - 830057 - - - 1.5509 - 2.277 0.562 - 488.6 1 2 0 0.0021 12 0 0 0 1.26E+07 1.10E+07 - - - 5.3563 0.9999 221125_WJC_METTL3_EV_vs_WT_F05.11598.11598.3 0.00174 13/44 R.VNVPVIGGHAGK[136.11].T "sp|P40926|MDHM_HUMAN,tr|G3XAL0|G3XAL0_HUMAN" 2 1154.6651 1.46 63752 11598 3 1154.664567 385.8957 "Malate dehydrogenase, mitochondrial OS=Homo sapiens OX=9606 GN=MDH2 PE=1 SV=3" 8.73 2297.9 - 705807 - - - -0.498 - 2.281 0.388 - 243.3 1 2 0 -0.0006 12 0 0 0 2.65E+07 1.81E+07 - - - 5.1514 0.9999 221125_WJC_METTL3_EV_vs_WT_F05.11599.11599.2 6.23E-06 18-Oct K.YSQYQQAIYK.C "sp|O14744|ANM5_HUMAN,tr|H0YJ77|H0YJ77_HUMAN,tr|G3V5T6|G3V5T6_HUMAN,tr|H0YJX6|H0YJX6_HUMAN" 4 1290.6245 1.74 63753 11599 2 1290.625514 646.3195 Protein arginine N-methyltransferase 5 OS=Homo sapiens OX=9606 GN=PRMT5 PE=1 SV=4 8.43 2298.1 - 574487 - - - 0.8229 - 1.914 0.539 - 264 1 2 0 0.0011 10 0 0 0 8.83E+06 5.07E+06 - - - 4.8338 0.999 221125_WJC_METTL3_EV_vs_WT_F05.11600.11600.3 0.0871 13/40 R.K[136.11]LDPEIVPEEK[136.11].D "sp|O43148|MCES_HUMAN,tr|K7EPP5|K7EPP5_HUMAN" 2 1311.7257 0.9 63754 11600 3 1311.728246 438.2492 mRNA cap guanine-N7 methyltransferase OS=Homo sapiens OX=9606 GN=RNMT PE=1 SV=1 4.41 2298.1 - 542133 - - - 1.9539 - 2.38 0.25 - 299.2 1 2 0 0.0026 11 0 0 0 4.35E+06 4.84E+06 - - - 3.7898 0.9975 221125_WJC_METTL3_EV_vs_WT_F05.11601.11601.3 1.84E-06 Nov-48 R.ALVDHENVISC[160.03]PH.L "sp|O43175|SERA_HUMAN,tr|A0A286YF78|A0A286YF78_HUMAN,tr|A0A2C9F2M7|A0A2C9F2M7_HUMAN,tr|A0A286YF22|A0A286YF22_HUMAN,tr|A0A286YFL2|A0A286YFL2_HUMAN,tr|A0A286YFA2|A0A286YFA2_HUMAN" 6 1489.6984 - 63755 11601 3 1489.698685 497.5734 D-3-phosphoglycerate dehydrogenase OS=Homo sapiens OX=9606 GN=PHGDH PE=1 SV=4 5.15 2298.3 - 506312 - - - 0.2162 - 2.368 0.53 - 146.7 1 1 0 0.0003 13 0 0 0 - - - - - 6.7861 0.9997 221125_WJC_METTL3_EV_vs_WT_F05.11606.11606.2 1.05E-05 16-Nov R.GDFSVHISR[166.11].N "sp|O00746|NDKM_HUMAN,tr|Q4TT34|Q4TT34_HUMAN,tr|A0A087WVT9|A0A087WVT9_HUMAN,tr|F2Z2X0|F2Z2X0_HUMAN" 4 1026.5122 1.95 63758 11606 2 1026.513461 514.2634 "Nucleoside diphosphate kinase, mitochondrial OS=Homo sapiens OX=9606 GN=NME4 PE=1 SV=1" 6.74 2298.9 - 1.99E+06 - - - 1.2158 - 1.912 0.434 - 301 1 2 0 0.0012 9 0 0 0 3.02E+08 1.55E+08 - - - 4.1213 1 221125_WJC_METTL3_EV_vs_WT_F05.11607.11607.3 5.13E-07 17/56 R.YYDSRPGGYGYGYGR.S sp|P98179|RBM3_HUMAN 1 1729.7485 1.08 63759 11607 3 1729.750746 577.5901 RNA-binding protein 3 OS=Homo sapiens OX=9606 GN=RBM3 PE=1 SV=1 8.38 2299.1 - 865889 - - - 1.3077 - 2.384 0.611 - 185.6 1 2 0 0.0023 15 0 0 0 7.58E+07 7.00E+07 - - - 7.6184 0.9274 221125_WJC_METTL3_EV_vs_WT_F05.11608.11608.2 0.00884 12-Aug D.FSVHISR[166.11].N "sp|O00746|NDKM_HUMAN,tr|Q4TT34|Q4TT34_HUMAN,tr|A0A087WVT9|A0A087WVT9_HUMAN,tr|F2Z2X0|F2Z2X0_HUMAN" 4 854.4638 3.21 63760 11608 2 854.463932 428.2392 "Nucleoside diphosphate kinase, mitochondrial OS=Homo sapiens OX=9606 GN=NME4 PE=1 SV=1" 9.76 2299.1 - 2.95E+06 - - - 0.1475 - 1.573 0.227 - 302.7 1 1 0 0.0001 7 0 0 0 6.72E+08 2.09E+08 - - - 2.1529 1 221125_WJC_METTL3_EV_vs_WT_F05.11612.11612.3 1.48E-09 15/48 K.HLVESTNEMAPLK[136.11].V sp|Q9NYU2|UGGG1_HUMAN 1 1475.7534 0.1 63764 11612 3 1475.75685 492.9251 UDP-glucose:glycoprotein glucosyltransferase 1 OS=Homo sapiens OX=9606 GN=UGGT1 PE=1 SV=3 5.4 2299.6 - 437550 - - - 2.3615 - 2.732 0.608 - 143.2 1 2 0 0.0035 13 0 0 0 2.88E+05 2.86E+06 - - - 8.0426 0.9821 221125_WJC_METTL3_EV_vs_WT_F05.11613.11613.2 0.0733 18-Aug L.AEFATGNDR[166.11]K[136.11].E "sp|P62258|1433E_HUMAN,tr|K7EM20|K7EM20_HUMAN" 2 1125.5534 0.48 63765 11613 2 1125.553838 563.784 14-3-3 protein epsilon OS=Homo sapiens OX=9606 GN=YWHAE PE=1 SV=1 6.11 2299.7 - 421862 - - - 0.4282 - 1.805 0.4 - 240.7 1 1 0 0.0005 10 0 0 0 2.49E+06 5.24E+06 - - - 3.6437 0.9997 221125_WJC_METTL3_EV_vs_WT_F05.11616.11616.2 0.000676 20-Oct K.DIQEESTFSSR[166.11].K "sp|P42704|LPPRC_HUMAN,tr|A0A804HI14|A0A804HI14_HUMAN,tr|A0A804HL40|A0A804HL40_HUMAN,tr|A0A804HKJ0|A0A804HKJ0_HUMAN,tr|A0A804HKR3|A0A804HKR3_HUMAN,tr|A0A0C4DG06|A0A0C4DG06_HUMAN,tr|A0A804HIN4|A0A804HIN4_HUMAN,tr|A0A804HLG8|A0A804HLG8_HUMAN,tr|A0A804HIV5|A0A804HIV5_HUMAN,tr|A0A804HHY9|A0A804HHY9_HUMAN,tr|A0A804HJH8|A0A804HJH8_HUMAN,tr|B8ZZ38|B8ZZ38_HUMAN,tr|A0A804HI40|A0A804HI40_HUMAN,tr|A0A804HJZ1|A0A804HJZ1_HUMAN,tr|C9JCA9|C9JCA9_HUMAN,tr|A0A804HIQ7|A0A804HIQ7_HUMAN,tr|A0A804HK30|A0A804HK30_HUMAN,tr|A0A804HKI2|A0A804HKI2_HUMAN,tr|A0A804HIG4|A0A804HIG4_HUMAN,tr|A0A804HK02|A0A804HK02_HUMAN" 20 1307.5869 0.14 63768 11616 2 1307.585265 654.8007 "Leucine-rich PPR motif-containing protein, mitochondrial OS=Homo sapiens OX=9606 GN=LRPPRC PE=1 SV=3" 4.14 2300.1 - 326523 - - - -1.2458 - 2.004 0.437 - 337.5 1 2 0 -0.0016 11 0 0 0 3.53E+05 2.56E+06 - - - 4.1487 0.857 221125_WJC_METTL3_EV_vs_WT_F05.11618.11618.2 5.9 16-Jun R.IR[166.11]VDYSITK[136.11].R sp|Q13595|TRA2A_HUMAN 1 1111.6356 1.37 63770 11618 2 1111.63765 556.8251 Transformer-2 protein homolog alpha OS=Homo sapiens OX=9606 GN=TRA2A PE=1 SV=1 8.59 2300.3 - 188817 - - - 1.818 - 1.408 0.111 - 164.9 1 2 1 0.002 9 0 0 0 6.92E+06 5.04E+06 - - - 0.8501 0.9999 221125_WJC_METTL3_EV_vs_WT_F05.11621.11621.2 2.05E-05 16-Nov R.GDFSVHISR.N "sp|O00746|NDKM_HUMAN,tr|Q4TT34|Q4TT34_HUMAN,tr|A0A087WVT9|A0A087WVT9_HUMAN,tr|F2Z2X0|F2Z2X0_HUMAN" 4 1016.5039 1.94 63772 11621 2 1016.503961 509.2592 "Nucleoside diphosphate kinase, mitochondrial OS=Homo sapiens OX=9606 GN=NME4 PE=1 SV=1" 6.74 2300.7 - 9.93E+06 - - - 0.0177 - 2.164 0.516 - 453.5 1 2 0 0 9 0 0 0 3.02E+08 1.55E+08 - - - 5.0855 1 221125_WJC_METTL3_EV_vs_WT_F05.11622.11622.3 8.33E-06 17/48 K.AYLEEEC[160.03]PATLRK.Y "sp|P25311|ZA2G_HUMAN,tr|C9JEV0|C9JEV0_HUMAN" 2 1578.7712 142.39 63773 11622 3 1578.768965 527.2643 Zinc-alpha-2-glycoprotein OS=Homo sapiens OX=9606 GN=AZGP1 PE=1 SV=2 4.79 2300.8 - 1.98E+06 - - - -1.4112 - 2.956 0.563 - 380.7 1 2 0 -0.0022 13 0 0 0 1.82E+07 1.28E+05 - - - 7.7549 0.8582 221125_WJC_METTL3_EV_vs_WT_F05.11624.11624.2 0.00176 14-Aug G.DFSVHISR.N "sp|O00746|NDKM_HUMAN,tr|Q4TT34|Q4TT34_HUMAN,tr|A0A087WVT9|A0A087WVT9_HUMAN,tr|F2Z2X0|F2Z2X0_HUMAN" 4 959.4825 1.99 63775 11624 2 959.482008 480.7485 "Nucleoside diphosphate kinase, mitochondrial OS=Homo sapiens OX=9606 GN=NME4 PE=1 SV=1" 6.74 2300.9 - 2.15E+06 - - - -0.4909 - 1.704 0.124 - 328.7 1 1 0 -0.0005 8 0 0 0 6.79E+07 3.41E+07 - - - 1.5642 0.9999 221125_WJC_METTL3_EV_vs_WT_F05.11625.11625.2 1.27E-05 20-Oct K.DISTNYYASQK.K "sp|P14625|ENPL_HUMAN,tr|A0A7P0T917|A0A7P0T917_HUMAN,tr|A0A7P0TAE1|A0A7P0TAE1_HUMAN,tr|H0YIV0|H0YIV0_HUMAN,tr|A0A087WT78|A0A087WT78_HUMAN,tr|A0A7P0TAT8|A0A7P0TAT8_HUMAN" 6 1288.5935 0.97 63776 11625 2 1288.594229 645.304 Endoplasmin OS=Homo sapiens OX=9606 GN=HSP90B1 PE=1 SV=1 5.83 2301 - 2.02E+06 - - - 0.53 - 2.017 0.579 - 206.4 1 2 0 0.0007 11 0 0 0 1.99E+07 2.05E+07 - - - 5.2153 0.9999 221125_WJC_METTL3_EV_vs_WT_F05.11626.11626.2 2.23E-05 20-Oct K.DISTNYYASQK[136.11].K "sp|P14625|ENPL_HUMAN,tr|A0A7P0T917|A0A7P0T917_HUMAN,tr|A0A7P0TAE1|A0A7P0TAE1_HUMAN,tr|H0YIV0|H0YIV0_HUMAN,tr|A0A087WT78|A0A087WT78_HUMAN,tr|A0A7P0TAT8|A0A7P0TAT8_HUMAN" 6 1296.6077 0.97 63777 11626 2 1296.60785 649.3111 Endoplasmin OS=Homo sapiens OX=9606 GN=HSP90B1 PE=1 SV=1 5.83 2301 - 1.87E+06 - - - 0.0802 - 2.116 0.587 - 211 1 2 0 0.0001 11 0 0 0 1.99E+07 2.05E+07 - - - 5.4042 0.9482 221125_WJC_METTL3_EV_vs_WT_F05.11627.11627.2 0.000681 14-Sep G.DFSVHISR[166.11].N "sp|O00746|NDKM_HUMAN,tr|Q4TT34|Q4TT34_HUMAN,tr|A0A087WVT9|A0A087WVT9_HUMAN,tr|F2Z2X0|F2Z2X0_HUMAN" 4 969.4907 1.99 63778 11627 2 969.492232 485.7527 "Nucleoside diphosphate kinase, mitochondrial OS=Homo sapiens OX=9606 GN=NME4 PE=1 SV=1" 6.74 2301.1 - 1.56E+06 - - - 1.5297 - 1.847 0.283 - 382.9 1 1 0 0.0015 8 0 0 0 6.79E+07 3.41E+07 - - - 2.9812 1 221125_WJC_METTL3_EV_vs_WT_F05.11628.11628.3 0.000542 Nov-44 K.LHGWAPGPDYQK.S sp|Q5JSZ5|PRC2B_HUMAN 1 1367.6622 1.71 63779 11628 3 1367.661827 456.8947 Protein PRRC2B OS=Homo sapiens OX=9606 GN=PRRC2B PE=1 SV=2 6.74 2301.1 - 1.34E+06 - - - -0.2983 - 2.332 0.516 - 173.6 1 2 0 -0.0004 12 0 0 0 7.77E+06 4.54E+06 - - - 6.6398 0.9988 221125_WJC_METTL3_EV_vs_WT_F05.11629.11629.3 0.0298 Sep-44 K.GSYVSIHSSGFR.D "sp|Q13838|DX39B_HUMAN,sp|O00148|DX39A_HUMAN,tr|K7EL56|K7EL56_HUMAN,tr|K7EPJ3|K7EPJ3_HUMAN,tr|F6U6E2|F6U6E2_HUMAN,tr|F6TRA5|F6TRA5_HUMAN,tr|A0A0G2JHN7|A0A0G2JHN7_HUMAN,tr|F6S2B7|F6S2B7_HUMAN,tr|F6WLT2|F6WLT2_HUMAN,tr|Q5STU3|Q5STU3_HUMAN,tr|F6R6M7|F6R6M7_HUMAN,tr|F6QYI9|F6QYI9_HUMAN,tr|K7ENP6|K7ENP6_HUMAN,tr|A0A0G2JJL7|A0A0G2JJL7_HUMAN,tr|K7EIL8|K7EIL8_HUMAN,tr|K7EQN7|K7EQN7_HUMAN,tr|K7EN69|K7EN69_HUMAN,tr|F6S4E6|F6S4E6_HUMAN,tr|A0A0A0MT12|A0A0A0MT12_HUMAN,tr|F6SXL5|F6SXL5_HUMAN" 20 1295.6258 0.83 63780 11629 3 1295.62829 432.8826 Spliceosome RNA helicase DDX39B OS=Homo sapiens OX=9606 GN=DDX39B PE=1 SV=1 8.75 2301.2 - 1.18E+06 - - - 1.884 - 1.933 0.293 - 85.5 1 2 0 0.0024 12 0 0 0 4.97E+07 5.95E+07 - - - 3.6328 0.9994 221125_WJC_METTL3_EV_vs_WT_F05.11630.11630.3 0.00184 Jul-40 K.IHPTSVISGYR.L "sp|P17987|TCPA_HUMAN,tr|F5H136|F5H136_HUMAN,tr|E7ERF2|E7ERF2_HUMAN,tr|F5H676|F5H676_HUMAN" 4 1228.6564 0.34 63781 11630 3 1228.656075 410.5594 T-complex protein 1 subunit alpha OS=Homo sapiens OX=9606 GN=TCP1 PE=1 SV=1 8.75 2301.3 - 1.17E+06 - - - -0.2816 - 1.655 0.335 - 58.3 1 2 0 -0.0003 11 0 0 0 1.06E+07 3.17E+07 - - - 3.706 0.9948 221125_WJC_METTL3_EV_vs_WT_F05.11631.11631.3 0.00424 Nov-40 R.FTAFKEEYEGK.E "sp|Q12996|CSTF3_HUMAN,tr|E9PLP8|E9PLP8_HUMAN" 2 1347.6347 1.06 63782 11631 3 1347.631861 450.2188 Cleavage stimulation factor subunit 3 OS=Homo sapiens OX=9606 GN=CSTF3 PE=1 SV=1 4.79 2301.4 - 854099 - - - -2.094 - 2.079 0.276 - 92.6 1 2 1 -0.0028 11 0 0 0 1.08E+07 1.02E+07 - - - 3.6955 0.9999 221125_WJC_METTL3_EV_vs_WT_F05.11632.11632.3 0.000147 13/44 K.LHGWAPGPDYQK[136.11].S sp|Q5JSZ5|PRC2B_HUMAN 1 1375.6764 1.68 63783 11632 3 1375.677372 459.5661 Protein PRRC2B OS=Homo sapiens OX=9606 GN=PRRC2B PE=1 SV=2 6.74 2301.5 - 788556 - - - 0.6811 - 2.331 0.421 - 230.4 1 2 0 0.0009 12 0 0 0 9.10E+06 5.42E+06 - - - 5.5793 0.9993 221125_WJC_METTL3_EV_vs_WT_F05.11636.11636.3 0.0159 16/60 K.SPGVAAAVAEDGGLK[136.11]K[136.11].C "sp|Q9BTE7|DCNL5_HUMAN,tr|E9PLS2|E9PLS2_HUMAN,tr|E9PQV9|E9PQV9_HUMAN,tr|E9PM78|E9PM78_HUMAN,tr|E9PM04|E9PM04_HUMAN,tr|H0YD80|H0YD80_HUMAN,tr|E9PLH8|E9PLH8_HUMAN" 7 1484.817 1.22 63787 11636 3 1484.8194 495.9463 DCN1-like protein 5 OS=Homo sapiens OX=9606 GN=DCUN1D5 PE=1 SV=1 5.79 2302 - 346918 - - - 1.6446 - 2.088 0.312 - 238 1 2 0 0.0024 16 0 0 0 4.89E+06 4.01E+06 - - - 3.9068 0.9998 221125_WJC_METTL3_EV_vs_WT_F05.11640.11640.3 0.00618 13/44 K.GGGHVAQIYAIR[166.11].Q "sp|P62249|RS16_HUMAN,tr|M0R210|M0R210_HUMAN,tr|M0R3H0|M0R3H0_HUMAN,tr|M0QX76|M0QX76_HUMAN,tr|M0R1M5|M0R1M5_HUMAN" 5 1250.6759 0.89 63790 11640 3 1250.6741 417.8993 40S ribosomal protein S16 OS=Homo sapiens OX=9606 GN=RPS16 PE=1 SV=2 8.75 2302.4 - 4.12E+06 - - - -1.4592 - 2.071 0.392 - 285.5 1 2 0 -0.0018 12 0 0 0 1.30E+08 1.46E+08 - - - 4.9279 1 221125_WJC_METTL3_EV_vs_WT_F05.11643.11643.3 3.52E-08 17/56 R.TIQRPVTMGDEGGLR.R "sp|Q14527|HLTF_HUMAN,tr|H7C5K0|H7C5K0_HUMAN,tr|A0A0C4DGA6|A0A0C4DGA6_HUMAN" 3 1628.8304 1.23 63793 11643 3 1628.828468 543.9508 Helicase-like transcription factor OS=Homo sapiens OX=9606 GN=HLTF PE=1 SV=2 5.74 2302.6 - 1.18E+06 - - - -1.2101 - 2.862 0.596 - 292.8 1 2 0 -0.002 15 0 0 0 8.52E+06 6.91E+06 - - - 7.9281 0.9997 221125_WJC_METTL3_EV_vs_WT_F05.11646.11646.2 2.67E-05 24-Dec M.GVQVETISPGDGR[166.11].T "sp|P62942|FKB1A_HUMAN,tr|A0A087WZM5|A0A087WZM5_HUMAN,tr|A0A7I2V3S6|A0A7I2V3S6_HUMAN,tr|Q1JUQ3|Q1JUQ3_HUMAN,tr|A0A087WTS4|A0A087WTS4_HUMAN,tr|A0A087WV48|A0A087WV48_HUMAN,tr|Q5W0X3|Q5W0X3_HUMAN" 7 1323.6658 0.96 63796 11646 2 1323.662803 662.8402 Peptidyl-prolyl cis-trans isomerase FKBP1A OS=Homo sapiens OX=9606 GN=FKBP1A PE=1 SV=2 4.37 2302.9 - 744558 - - - -2.274 - 2.688 0.453 - 576.9 1 2 0 -0.003 13 0 0 0 7.42E+06 7.74E+06 - - - 4.9237 0.9997 221125_WJC_METTL3_EV_vs_WT_F05.11650.11650.2 0.0626 24-Nov M.GVQVETISPGDGR.T "sp|P62942|FKB1A_HUMAN,tr|A0A087WZM5|A0A087WZM5_HUMAN,tr|A0A7I2V3S6|A0A7I2V3S6_HUMAN,tr|Q1JUQ3|Q1JUQ3_HUMAN,tr|A0A087WTS4|A0A087WTS4_HUMAN,tr|A0A087WV48|A0A087WV48_HUMAN,tr|Q5W0X3|Q5W0X3_HUMAN" 7 1313.6575 0.96 63800 11650 2 1313.656751 657.836 Peptidyl-prolyl cis-trans isomerase FKBP1A OS=Homo sapiens OX=9606 GN=FKBP1A PE=1 SV=2 4.37 2303.5 - 487183 - - - -0.6029 - 2.027 0.355 - 401.8 1 2 0 -0.0008 13 0 0 0 7.42E+06 7.74E+06 - - - 3.4762 1 221125_WJC_METTL3_EV_vs_WT_F05.11653.11653.2 5.14E-09 15/34 L.YQGAGGPGPGGFGAQGPK.G "sp|P0DMV8|HS71A_HUMAN,sp|P0DMV9|HS71B_HUMAN,tr|V9GZ37|V9GZ37_HUMAN,tr|A0A0G2JIW1|A0A0G2JIW1_HUMAN" 4 1601.7587 0.14 63803 11653 2 1601.755924 801.8866 Heat shock 70 kDa protein 1A OS=Homo sapiens OX=9606 GN=HSPA1A PE=1 SV=1 8.59 2303.9 - 298263 - - - -1.7044 - 3.189 0.647 - 529.9 1 1 0 -0.0027 18 0 0 0 2.16E+06 1.54E+07 - - - 6.6701 0.9982 221125_WJC_METTL3_EV_vs_WT_F05.11654.11654.2 0.00979 28-May R.YYDSR[166.11]PGGYGYGYGR[166.11].S sp|P98179|RBM3_HUMAN 1 1749.765 0.71 63804 11654 2 1749.761875 875.8898 RNA-binding protein 3 OS=Homo sapiens OX=9606 GN=RBM3 PE=1 SV=1 8.38 2304 - 236901 - - - -1.7997 - 1.056 0.437 - 22.1 1 2 0 -0.0031 15 0 0 0 1.83E+06 2.56E+06 - - - 2.4017 1 221125_WJC_METTL3_EV_vs_WT_F05.11656.11656.2 4.12E-08 14/28 R.APSTYGGGLSVSSSR.F sp|P02533|K1C14_HUMAN 1 1424.6896 11.51 63805 11656 2 1424.689011 713.3521 "Keratin, type I cytoskeletal 14 OS=Homo sapiens OX=9606 GN=KRT14 PE=1 SV=4" 8.79 2304.2 - 493360 - - - -0.3938 - 2.899 0.592 - 576.7 1 2 0 -0.0006 15 0 0 0 7.31E+06 6.36E+05 - - - 6.0301 1 221125_WJC_METTL3_EV_vs_WT_F05.11658.11658.3 2.45E-06 13/56 R.YYDSR[166.11]PGGYGYGYGR[166.11].S sp|P98179|RBM3_HUMAN 1 1749.765 1.08 63806 11658 3 1749.764934 584.2623 RNA-binding protein 3 OS=Homo sapiens OX=9606 GN=RBM3 PE=1 SV=1 8.38 2304.4 - 1.03E+07 - - - -0.0514 - 2.031 0.601 - 120.8 1 2 0 -0.0001 15 0 0 0 7.58E+07 7.00E+07 - - - 7.0893 0.9997 221125_WJC_METTL3_EV_vs_WT_F05.11659.11659.3 0.00139 Dec-44 K.GGGHVAQIYAIR.Q "sp|P62249|RS16_HUMAN,tr|M0R210|M0R210_HUMAN,tr|M0R3H0|M0R3H0_HUMAN,tr|M0QX76|M0QX76_HUMAN,tr|M0R1M5|M0R1M5_HUMAN" 5 1240.6677 0.83 63807 11659 3 1240.667904 414.5632 40S ribosomal protein S16 OS=Homo sapiens OX=9606 GN=RPS16 PE=1 SV=2 8.75 2304.5 - 6.94E+06 - - - 0.2007 - 2.189 0.306 - 177.6 1 2 0 0.0003 12 0 0 0 1.19E+08 1.44E+08 - - - 4.1231 0.9996 221125_WJC_METTL3_EV_vs_WT_F05.11662.11662.2 5.41E-05 22-Nov K.GSYVSIHSSGFR[166.11].D "sp|Q13838|DX39B_HUMAN,sp|O00148|DX39A_HUMAN,tr|K7EL56|K7EL56_HUMAN,tr|K7EPJ3|K7EPJ3_HUMAN,tr|F6U6E2|F6U6E2_HUMAN,tr|F6TRA5|F6TRA5_HUMAN,tr|A0A0G2JHN7|A0A0G2JHN7_HUMAN,tr|F6S2B7|F6S2B7_HUMAN,tr|F6WLT2|F6WLT2_HUMAN,tr|Q5STU3|Q5STU3_HUMAN,tr|F6R6M7|F6R6M7_HUMAN,tr|F6QYI9|F6QYI9_HUMAN,tr|K7ENP6|K7ENP6_HUMAN,tr|A0A0G2JJL7|A0A0G2JJL7_HUMAN,tr|K7EIL8|K7EIL8_HUMAN,tr|K7EQN7|K7EQN7_HUMAN,tr|K7EN69|K7EN69_HUMAN,tr|F6S4E6|F6S4E6_HUMAN,tr|A0A0A0MT12|A0A0A0MT12_HUMAN,tr|F6SXL5|F6SXL5_HUMAN" 20 1305.6341 0.29 63810 11662 2 1305.633659 653.8243 Spliceosome RNA helicase DDX39B OS=Homo sapiens OX=9606 GN=DDX39B PE=1 SV=1 8.75 2304.7 - 834436 - - - -0.3523 - 1.936 0.323 - 272.7 1 2 0 -0.0005 12 0 0 0 4.41E+06 1.54E+07 - - - 3.1647 0.9995 221125_WJC_METTL3_EV_vs_WT_F05.11663.11663.2 3.68E-08 13/22 K.GGGHVAQIYAIR[166.11].Q "sp|P62249|RS16_HUMAN,tr|M0R210|M0R210_HUMAN,tr|M0R3H0|M0R3H0_HUMAN,tr|M0QX76|M0QX76_HUMAN,tr|M0R1M5|M0R1M5_HUMAN" 5 1250.6759 0.9 63811 11663 2 1250.672055 626.3452 40S ribosomal protein S16 OS=Homo sapiens OX=9606 GN=RPS16 PE=1 SV=2 8.75 2304.9 - 702995 - - - -3.0943 - 2.121 0.583 - 518.3 1 2 0 -0.0039 12 0 0 0 1.27E+07 1.41E+07 - - - 5.3242 0.9999 221125_WJC_METTL3_EV_vs_WT_F05.11664.11664.2 4.17E-06 18-Nov K.EDQTEYLEER[166.11].R "sp|P08238|HS90B_HUMAN,sp|Q58FF6|H90B4_HUMAN,sp|Q58FF7|H90B3_HUMAN,sp|P07900|HS90A_HUMAN,tr|G3V2J8|G3V2J8_HUMAN" 5 1320.5709 0.77 63812 11664 2 1320.569609 661.2927 Heat shock protein HSP 90-beta OS=Homo sapiens OX=9606 GN=HSP90AB1 PE=1 SV=4 3.91 2305 - 692693 - - - -0.9852 - 2.242 0.536 - 685 1 2 0 -0.0013 10 0 0 0 7.51E+07 9.70E+07 - - - 5.2531 1 221125_WJC_METTL3_EV_vs_WT_F05.11665.11665.3 2.52E-10 16/56 R.TIQR[166.11]PVTMGDEGGLR[166.11].R "sp|Q14527|HLTF_HUMAN,tr|H7C5K0|H7C5K0_HUMAN,tr|A0A0C4DGA6|A0A0C4DGA6_HUMAN" 3 1648.847 1.23 63813 11665 3 1648.846168 550.6229 Helicase-like transcription factor OS=Homo sapiens OX=9606 GN=HLTF PE=1 SV=2 5.74 2305.1 - 688355 - - - -0.4919 - 2.743 0.629 - 246.4 1 2 0 -0.0008 15 0 0 0 8.52E+06 6.91E+06 - - - 8.1855 0.9997 221125_WJC_METTL3_EV_vs_WT_F05.11668.11668.2 3.17E-07 22-Dec R.QQEELLAEENQR.L "sp|Q15149|PLEC_HUMAN,tr|H0YDN1|H0YDN1_HUMAN" 2 1485.706 1.54 63816 11668 2 1485.708972 743.8603 Plectin OS=Homo sapiens OX=9606 GN=PLEC PE=1 SV=3 4.09 2305.5 - 510115 - - - 2.034 - 2.327 0.468 - 587.2 1 2 0 0.003 12 0 0 0 8.38E+06 5.45E+06 - - - 4.7189 0.9991 221125_WJC_METTL3_EV_vs_WT_F05.11672.11672.2 0.00501 28-Jun R.YYDSRPGGYGYGYGR.S sp|P98179|RBM3_HUMAN 1 1729.7485 0.71 63820 11672 2 1729.750379 865.8815 RNA-binding protein 3 OS=Homo sapiens OX=9606 GN=RBM3 PE=1 SV=1 8.38 2306 - 214413 - - - 1.0955 - 1.183 0.451 - 32.7 1 2 0 0.0019 15 0 0 0 1.83E+06 2.56E+06 - - - 2.7847 0.9999 221125_WJC_METTL3_EV_vs_WT_F05.11676.11676.2 0.000271 18-Dec K.EDQTEYLEER.R "sp|P08238|HS90B_HUMAN,sp|Q58FF6|H90B4_HUMAN,sp|Q58FF7|H90B3_HUMAN,sp|P07900|HS90A_HUMAN,tr|G3V2J8|G3V2J8_HUMAN" 5 1310.5626 0.77 63822 11676 2 1310.563017 656.2886 Heat shock protein HSP 90-beta OS=Homo sapiens OX=9606 GN=HSP90AB1 PE=1 SV=4 3.91 2306.5 - 1.42E+06 - - - 0.2877 - 2.323 0.544 - 795.5 1 2 0 0.0004 10 0 0 0 7.51E+07 9.70E+07 - - - 5.4115 0.9999 221125_WJC_METTL3_EV_vs_WT_F05.11677.11677.2 1.70E-05 22-Dec K.GGGHVAQIYAIR.Q "sp|P62249|RS16_HUMAN,tr|M0R210|M0R210_HUMAN,tr|M0R3H0|M0R3H0_HUMAN,tr|M0QX76|M0QX76_HUMAN,tr|M0R1M5|M0R1M5_HUMAN" 5 1240.6677 0.59 63823 11677 2 1240.668145 621.3411 40S ribosomal protein S16 OS=Homo sapiens OX=9606 GN=RPS16 PE=1 SV=2 8.75 2306.7 - 941409 - - - 0.3949 - 2.086 0.491 - 334 1 2 0 0.0005 12 0 0 0 1.23E+07 2.09E+07 - - - 4.6019 0.9972 221125_WJC_METTL3_EV_vs_WT_F05.11678.11678.2 0.0741 14-Jul K.NIHLNLDR.R "sp|Q9Y5S9|RBM8A_HUMAN,tr|A0A0J9YW13|A0A0J9YW13_HUMAN" 2 993.5356 1.56 63824 11678 2 993.535101 497.7751 RNA-binding protein 8A OS=Homo sapiens OX=9606 GN=RBM8A PE=1 SV=1 6.74 2306.8 - 835477 - - - -0.4801 - 1.269 0.242 - 242.9 1 2 0 -0.0005 8 0 0 0 1.08E+07 6.90E+06 - - - 1.5468 0.9999 221125_WJC_METTL3_EV_vs_WT_F05.11679.11679.2 0.000411 22-Dec R.QQEELLAEENQR[166.11].L "sp|Q15149|PLEC_HUMAN,tr|H0YDN1|H0YDN1_HUMAN" 2 1495.7142 1.54 63825 11679 2 1495.714102 748.8644 Plectin OS=Homo sapiens OX=9606 GN=PLEC PE=1 SV=3 4.09 2306.9 - 597871 - - - -0.0789 - 2.339 0.524 - 586.6 1 2 0 -0.0001 12 0 0 0 8.38E+06 5.45E+06 - - - 5.147 0.9948 221125_WJC_METTL3_EV_vs_WT_F05.11688.11688.3 0.0164 Oct-36 K.GK[136.11]IELEETIK[136.11].V "sp|P56556|NDUA6_HUMAN,tr|R4GN43|R4GN43_HUMAN,tr|A0A2Y9D025|A0A2Y9D025_HUMAN" 3 1174.678 1.67 63832 11688 3 1174.674946 392.5666 NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 6 OS=Homo sapiens OX=9606 GN=NDUFA6 PE=1 SV=4 4.79 2308 - 615244 - - - -2.6033 - 2.057 0.299 - 135.6 1 2 1 -0.0031 10 0 0 0 7.27E+06 4.35E+06 - - - 3.9791 0.9823 221125_WJC_METTL3_EV_vs_WT_F05.11689.11689.3 0.116 Nov-36 K.GKIELEETIK.V "sp|P56556|NDUA6_HUMAN,tr|R4GN43|R4GN43_HUMAN,tr|A0A2Y9D025|A0A2Y9D025_HUMAN" 3 1158.6496 1.68 63833 11689 3 1158.647769 387.2238 NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 6 OS=Homo sapiens OX=9606 GN=NDUFA6 PE=1 SV=4 4.79 2308.1 - 961983 - - - -1.5837 - 1.978 0.185 - 165.7 1 2 1 -0.0018 10 0 0 0 7.30E+06 4.35E+06 - - - 2.5941 0.9996 221125_WJC_METTL3_EV_vs_WT_F05.11691.11691.2 0.0236 16-Oct K.QHITLALEK.Q "sp|Q16891|MIC60_HUMAN,tr|B9A067|B9A067_HUMAN,tr|C9J406|C9J406_HUMAN,tr|H7C463|H7C463_HUMAN" 4 1051.6026 1.51 63835 11691 2 1051.602094 526.8086 MICOS complex subunit MIC60 OS=Homo sapiens OX=9606 GN=IMMT PE=1 SV=1 6.75 2308.4 - 434981 - - - -0.4764 - 1.801 0.354 - 327.2 1 2 0 -0.0005 9 0 0 0 7.80E+06 5.16E+06 - - - 3.3576 0.999 221125_WJC_METTL3_EV_vs_WT_F05.11694.11694.3 0.0044 Sep-44 K.SK[136.11]AELMEISEDK[136.11].T "sp|P05455|LA_HUMAN,tr|E9PGX9|E9PGX9_HUMAN,tr|E9PFL9|E9PFL9_HUMAN,tr|E7ERC4|E7ERC4_HUMAN" 4 1394.6934 1.02 63838 11694 3 1394.690834 465.9051 Lupus La protein OS=Homo sapiens OX=9606 GN=SSB PE=1 SV=2 4.41 2308.8 - 251390 - - - -1.8377 - 1.965 0.407 - 125 1 2 1 -0.0026 12 0 0 0 2.75E+06 2.70E+06 - - - 4.9493 1 221125_WJC_METTL3_EV_vs_WT_F05.11698.11698.3 0.000925 Dec-44 K.GSYVSIHSSGFR[166.11].D "sp|Q13838|DX39B_HUMAN,sp|O00148|DX39A_HUMAN,tr|K7EL56|K7EL56_HUMAN,tr|K7EPJ3|K7EPJ3_HUMAN,tr|F6U6E2|F6U6E2_HUMAN,tr|F6TRA5|F6TRA5_HUMAN,tr|A0A0G2JHN7|A0A0G2JHN7_HUMAN,tr|F6S2B7|F6S2B7_HUMAN,tr|F6WLT2|F6WLT2_HUMAN,tr|Q5STU3|Q5STU3_HUMAN,tr|F6R6M7|F6R6M7_HUMAN,tr|F6QYI9|F6QYI9_HUMAN,tr|K7ENP6|K7ENP6_HUMAN,tr|A0A0G2JJL7|A0A0G2JJL7_HUMAN,tr|K7EIL8|K7EIL8_HUMAN,tr|K7EQN7|K7EQN7_HUMAN,tr|K7EN69|K7EN69_HUMAN,tr|F6S4E6|F6S4E6_HUMAN,tr|A0A0A0MT12|A0A0A0MT12_HUMAN,tr|F6SXL5|F6SXL5_HUMAN" 20 1305.6341 0.84 63841 11698 3 1305.634289 436.2186 Spliceosome RNA helicase DDX39B OS=Homo sapiens OX=9606 GN=DDX39B PE=1 SV=1 8.75 2309.3 - 4.11E+06 - - - 0.1302 - 2.468 0.442 - 159.1 1 2 0 0.0002 12 0 0 0 5.02E+07 5.98E+07 - - - 5.9719 0.9968 221125_WJC_METTL3_EV_vs_WT_F05.11702.11702.3 0.000431 Oct-44 K.YAINPHLTEDQR.F sp|Q9ULX3|NOB1_HUMAN 1 1455.7106 0.5 63844 11702 3 1455.701616 486.2442 RNA-binding protein NOB1 OS=Homo sapiens OX=9606 GN=NOB1 PE=1 SV=1 5.32 2309.7 - 1.24E+06 - - - -6.2004 - 2 0.439 - 136 1 2 0 -0.009 12 0 0 0 9.46E+06 1.91E+07 - - - 5.3532 0.864 221125_WJC_METTL3_EV_vs_WT_F05.11703.11703.3 0.0947 Oct-48 K.AADAEAEVASLNR[166.11].R "sp|P06753|TPM3_HUMAN,tr|A0A2R2Y2Q3|A0A2R2Y2Q3_HUMAN,tr|J3KN67|J3KN67_HUMAN,tr|A0A494C0P6|A0A494C0P6_HUMAN" 4 1325.6451 0.94 63845 11703 3 1325.643661 442.889 Tropomyosin alpha-3 chain OS=Homo sapiens OX=9606 GN=TPM3 PE=1 SV=2 4.14 2309.8 - 488713 - - - -1.0689 - 1.802 0.025 - 145.9 2 2 0 -0.0014 13 0 0 0 4.41E+06 4.67E+06 - - - 0.2757 1 221125_WJC_METTL3_EV_vs_WT_F05.11704.11704.3 9.24E-06 20/68 K.LQGQAPGALEAGAAPAGR.R "sp|Q8N5A5|ZGPAT_HUMAN,tr|V9GY48|V9GY48_HUMAN" 2 1633.8536 2.44 63846 11704 3 1633.856387 545.6251 Zinc finger CCCH-type with G patch domain-containing protein OS=Homo sapiens OX=9606 GN=ZGPAT PE=1 SV=3 6 2309.9 - 456546 - - - 1.6948 - 3.158 0.518 - 341.4 1 2 0 0.0028 18 0 0 0 3.31E+06 1.36E+06 - - - 7.1779 0.9999 221125_WJC_METTL3_EV_vs_WT_F05.11708.11708.2 0.00121 13/34 K.LQGQAPGALEAGAAPAGR.R "sp|Q8N5A5|ZGPAT_HUMAN,tr|V9GY48|V9GY48_HUMAN" 2 1633.8536 2.11 63850 11708 2 1633.853669 817.9341 Zinc finger CCCH-type with G patch domain-containing protein OS=Homo sapiens OX=9606 GN=ZGPAT PE=1 SV=3 6 2310.4 - 359201 - - - 0.0312 - 3.07 0.515 - 254.5 1 2 0 0.0001 18 0 0 0 4.32E+06 2.04E+06 - - - 5.6025 1 221125_WJC_METTL3_EV_vs_WT_F05.11712.11712.2 2.29E-10 28-Dec R.SVFMSSTTSASGTGR.K sp|O94874|UFL1_HUMAN 1 1474.6722 3.31 63854 11712 2 1474.675921 738.3434 E3 UFM1-protein ligase 1 OS=Homo sapiens OX=9606 GN=UFL1 PE=1 SV=2 9.47 2310.9 - 255122 - - - 2.5185 - 2.813 0.657 - 513 1 2 0 0.0037 15 0 0 0 2.49E+06 7.51E+05 - - - 6.4352 1 221125_WJC_METTL3_EV_vs_WT_F05.11714.11714.2 1.35E-05 22-Sep R.C[160.03]EVC[160.03]DYETNVAR.N "sp|Q86UP3|ZFHX4_HUMAN,sp|Q15911|ZFHX3_HUMAN,tr|E5RI93|E5RI93_HUMAN,tr|E7EVZ1|E7EVZ1_HUMAN" 4 1514.613 1.57 63856 11714 2 1514.611406 758.3138 Zinc finger homeobox protein 4 OS=Homo sapiens OX=9606 GN=ZFHX4 PE=1 SV=1 4.14 2311.2 - 244591 - - - -1.0379 - 1.958 0.7 - 239.8 1 2 0 -0.0016 12 0 0 0 2.80E+06 1.79E+06 - - - 5.9787 0.9999 221125_WJC_METTL3_EV_vs_WT_F05.11715.11715.2 1.59E-06 22-Sep R.C[160.03]EVC[160.03]DYETNVAR[166.11].N "sp|Q86UP3|ZFHX4_HUMAN,sp|Q15911|ZFHX3_HUMAN,tr|E5RI93|E5RI93_HUMAN,tr|E7EVZ1|E7EVZ1_HUMAN" 4 1524.6212 1.41 63857 11715 2 1524.623588 763.3179 Zinc finger homeobox protein 4 OS=Homo sapiens OX=9606 GN=ZFHX4 PE=1 SV=1 4.14 2311.3 - 242927 - - - 1.5348 - 2.024 0.643 - 267 1 2 0 0.0023 12 0 0 0 2.53E+06 1.79E+06 - - - 5.6446 0.9998 221125_WJC_METTL3_EV_vs_WT_F05.11719.11719.2 0.000197 22-Aug R.ESDDGTEELEVR[166.11].L "sp|Q9NQX3|GEPH_HUMAN,tr|F5H039|F5H039_HUMAN" 2 1387.5979 1.55 63861 11719 2 1387.599481 694.8062 Gephyrin OS=Homo sapiens OX=9606 GN=GPHN PE=1 SV=1 3.77 2311.9 - 140069 - - - 1.1733 - 2.018 0.513 - 210.6 1 2 0 0.0016 12 0 0 0 1.55E+06 1.00E+06 - - - 4.6769 1 221125_WJC_METTL3_EV_vs_WT_F05.11721.11721.2 4.55E-08 13/26 R.APSTYGGGLSVSSR.F sp|P08779|K1C16_HUMAN 1 1337.6575 999 63862 11721 2 1337.657311 669.836 "Keratin, type I cytoskeletal 16 OS=Homo sapiens OX=9606 GN=KRT16 PE=1 SV=4" 8.79 2312.1 - 394051 - - - -0.1734 - 2.596 0.65 - 497.4 1 2 0 -0.0002 14 0 0 0 1.97E+07 0.00E+00 - - - 6.2358 0.8478 221125_WJC_METTL3_EV_vs_WT_F05.11723.11723.3 0.00217 Dec-44 R.EQAEAEVASLNR.R "tr|A0A494C0G0|A0A494C0G0_HUMAN,tr|A0A087WWU8|A0A087WWU8_HUMAN,tr|D6R904|D6R904_HUMAN" 3 1315.6368 0.91 63864 11723 3 1315.638297 439.5529 Tropomyosin alpha-3 chain (Fragment) OS=Homo sapiens OX=9606 GN=TPM3 PE=1 SV=1 4.25 2312.3 - 885469 - - - 1.1318 - 1.706 0.023 - 209.4 1 2 0 0.0015 12 0 0 0 4.41E+06 4.84E+06 - - - 0.2766 0.9519 221125_WJC_METTL3_EV_vs_WT_F05.11727.11727.2 0.0663 22-Sep R.SDSPVPTAPTSG.G "sp|Q86U44|MTA70_HUMAN,tr|B4E349|B4E349_HUMAN,tr|F5H6D8|F5H6D8_HUMAN,tr|B4DTN4|B4DTN4_HUMAN" 4 1114.5142 - 63868 11727 2 1114.515187 558.2644 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 3.8 2312.8 - 459600 - - - 0.856 - 1.444 0.368 - 224.4 1 1 0 0.001 12 0 0 0 - - - - - 2.7255 0.9997 221125_WJC_METTL3_EV_vs_WT_F05.11732.11732.2 6.58E-09 13/28 K.ALQGQISSQQVAVEK.L "sp|Q03001|DYST_HUMAN,tr|H0YC82|H0YC82_HUMAN,tr|E9PHM6|E9PHM6_HUMAN,tr|A0A494C1D7|A0A494C1D7_HUMAN,tr|F8W9J4|F8W9J4_HUMAN,tr|A0A7P0T890|A0A7P0T890_HUMAN,tr|F6QMI7|F6QMI7_HUMAN" 7 1584.8471 3.06 63873 11732 2 1584.850409 793.4308 Dystonin OS=Homo sapiens OX=9606 GN=DST PE=1 SV=4 6.05 2313.4 - 229455 - - - 2.0658 - 2.748 0.464 - 635.3 1 2 0 0.0033 15 0 0 0 1.12E+06 3.65E+05 - - - 4.9524 1 221125_WJC_METTL3_EV_vs_WT_F05.11733.11733.2 7.71E-07 16/34 K.LQGQAPGALEAGAAPAGR[166.11].R "sp|Q8N5A5|ZGPAT_HUMAN,tr|V9GY48|V9GY48_HUMAN" 2 1643.8619 2.11 63874 11733 2 1643.859129 822.9382 Zinc finger CCCH-type with G patch domain-containing protein OS=Homo sapiens OX=9606 GN=ZGPAT PE=1 SV=3 6 2313.6 - 217838 - - - -1.6784 - 2.584 0.594 - 497.2 1 2 0 -0.0028 18 0 0 0 4.32E+06 2.04E+06 - - - 5.7614 0.9972 221125_WJC_METTL3_EV_vs_WT_F05.11735.11735.2 0.0279 24-Aug K.QVKPLPAPLDGQR.K "sp|Q8WWY3|PRP31_HUMAN,tr|E7EVX8|E7EVX8_HUMAN" 2 1417.8041 2.82 63876 11735 2 1417.80583 709.9094 U4\U6 small nuclear ribonucleoprotein Prp31 OS=Homo sapiens OX=9606 GN=PRPF31 PE=1 SV=2 8.75 2313.8 - 160149 - - - 1.1863 - 1.429 0.252 - 68.9 1 2 0 0.0017 13 0 0 0 1.59E+06 5.64E+05 - - - 1.8179 0.9953 221125_WJC_METTL3_EV_vs_WT_F05.11736.11736.2 1.97E-07 22-Sep R.ESDDGTEELEVR.L "sp|Q9NQX3|GEPH_HUMAN,tr|F5H039|F5H039_HUMAN" 2 1377.5896 10.8 63877 11736 2 1377.580639 689.8021 Gephyrin OS=Homo sapiens OX=9606 GN=GPHN PE=1 SV=1 3.77 2314 - 154110 - - - -6.4925 - 2.28 0.586 - 467.3 1 2 0 -0.0089 12 0 0 0 1.53E+07 1.41E+06 - - - 5.5349 1 221125_WJC_METTL3_EV_vs_WT_F05.11739.11739.3 2.83E-05 13/48 K.QVKPLPAPLDGQR.K "sp|Q8WWY3|PRP31_HUMAN,tr|E7EVX8|E7EVX8_HUMAN" 2 1417.8041 2.3 63879 11739 3 1417.805963 473.6087 U4\U6 small nuclear ribonucleoprotein Prp31 OS=Homo sapiens OX=9606 GN=PRPF31 PE=1 SV=2 8.75 2314.3 - 5.89E+06 - - - 1.2801 - 2.336 0.488 - 259 1 2 0 0.0018 13 0 0 0 1.64E+08 7.14E+07 - - - 6.2806 0.9999 221125_WJC_METTL3_EV_vs_WT_F05.11740.11740.3 0.000741 Sep-44 R.TAAENDFVTLKK.D sp|P35908|K22E_HUMAN 1 1335.7034 0.01 63880 11740 3 1335.703371 446.2418 "Keratin, type II cytoskeletal 2 epidermal OS=Homo sapiens OX=9606 GN=KRT2 PE=1 SV=2" 5.73 2314.4 - 425666 - - - -0.0449 - 1.85 0.455 - 92 1 2 0 -0.0001 12 0 0 0 1.75E+07 1.32E+09 - - - 5.318 0.9997 221125_WJC_METTL3_EV_vs_WT_F05.11743.11743.3 0.000571 Dec-40 K.NFYQEHPDLAR.R "sp|P17844|DDX5_HUMAN,tr|J3QR02|J3QR02_HUMAN,tr|X6RLV5|X6RLV5_HUMAN,tr|A0A7I2V507|A0A7I2V507_HUMAN,tr|J3KTA4|J3KTA4_HUMAN,tr|J3KTQ4|J3KTQ4_HUMAN,tr|A0A7I2V2S0|A0A7I2V2S0_HUMAN,tr|J3QRQ7|J3QRQ7_HUMAN" 8 1388.6473 1.54 63883 11743 3 1388.650929 463.8897 Probable ATP-dependent RNA helicase DDX5 OS=Homo sapiens OX=9606 GN=DDX5 PE=1 SV=1 5.32 2314.6 - 1.84E+06 - - - 2.604 - 1.905 0.426 - 188.2 1 2 0 0.0036 11 0 0 0 1.50E+08 9.72E+07 - - - 5.1193 1 221125_WJC_METTL3_EV_vs_WT_F05.11744.11744.3 3.80E-05 16/44 K.QATFQSLHNGLR.A sp|P78560|CRADD_HUMAN 1 1370.7055 1.47 63884 11744 3 1370.7077 457.9091 Death domain-containing protein CRADD OS=Homo sapiens OX=9606 GN=CRADD PE=1 SV=1 9.76 2314.7 - 1.09E+06 - - - 1.6072 - 2.712 0.53 - 469.3 1 2 0 0.0022 12 0 0 0 3.93E+06 2.68E+06 - - - 7.2138 0.9999 221125_WJC_METTL3_EV_vs_WT_F05.11749.11749.2 6.53E-07 26-Dec R.ATTGTQTLLSSGTR.L "sp|Q8IX01|SUGP2_HUMAN,tr|M0R2Z9|M0R2Z9_HUMAN,tr|M0R3F6|M0R3F6_HUMAN" 3 1392.7209 0.89 63889 11749 2 1392.721789 697.3677 SURP and G-patch domain-containing protein 2 OS=Homo sapiens OX=9606 GN=SUGP2 PE=1 SV=2 9.79 2315.2 - 645665 - - - 0.6584 - 2.728 0.557 - 513.6 1 2 0 0.0009 14 0 0 0 5.17E+06 5.84E+06 - - - 5.6731 0.9995 221125_WJC_METTL3_EV_vs_WT_F05.11750.11750.3 0.00141 14/44 K.QATFQSLHNGLR[166.11].A sp|P78560|CRADD_HUMAN 1 1380.7138 1.75 63890 11750 3 1380.717371 461.2452 Death domain-containing protein CRADD OS=Homo sapiens OX=9606 GN=CRADD PE=1 SV=1 9.76 2315.3 - 634687 - - - 2.6102 - 2.298 0.352 - 263.5 1 2 0 0.0036 12 0 0 0 5.99E+06 3.43E+06 - - - 4.7697 0.9999 221125_WJC_METTL3_EV_vs_WT_F05.11751.11751.3 0.0331 13/36 R.NSTFTEHLYR[166.11].L sp|Q9BTE3|MCMBP_HUMAN 1 1276.6076 2.27 63891 11751 3 1276.605375 426.5431 Mini-chromosome maintenance complex-binding protein OS=Homo sapiens OX=9606 GN=MCMBP PE=1 SV=2 6.75 2315.4 - 424220 - - - -1.7194 - 2.553 0.409 - 376.5 1 2 0 -0.0022 10 0 0 0 7.91E+06 3.49E+06 - - - 5.8366 0.9999 221125_WJC_METTL3_EV_vs_WT_F05.11753.11753.3 6.85E-05 19/52 K.VVEVLAGHGHLYSR[166.11].L sp|P49327|FAS_HUMAN 1 1545.8291 0.65 63893 11753 3 1545.832354 516.2837 Fatty acid synthase OS=Homo sapiens OX=9606 GN=FASN PE=1 SV=3 6.89 2315.7 - 374023 - - - 2.085 - 3.362 0.414 - 590.8 1 2 0 0.0032 14 0 0 0 1.77E+06 2.72E+06 - - - 6.3772 1 221125_WJC_METTL3_EV_vs_WT_F05.11754.11754.4 1.98E-06 20/78 K.VVEVLAGHGHLYSR.L sp|P49327|FAS_HUMAN 1 1535.8209 0.58 63894 11754 4 1535.822804 384.9625 Fatty acid synthase OS=Homo sapiens OX=9606 GN=FASN PE=1 SV=3 6.89 2315.8 - 340721 - - - 1.2651 - 3.631 0.527 - 334.8 1 2 0 0.0019 14 0 0 0 2.01E+06 3.45E+06 - - - 4.2818 0.9987 221125_WJC_METTL3_EV_vs_WT_F05.11755.11755.2 0.00135 22-Aug K.GSFSDTGLGDGK[136.11].M "sp|Q9Y2W1|TR150_HUMAN,tr|A0A3B3ITZ9|A0A3B3ITZ9_HUMAN" 2 1147.5237 29.55 63895 11755 2 1147.526201 574.7691 Thyroid hormone receptor-associated protein 3 OS=Homo sapiens OX=9606 GN=THRAP3 PE=1 SV=2 4.21 2316 - 277520 - - - 2.1952 - 1.337 0.433 - 119.5 1 2 0 0.0025 12 0 0 0 4.68E+07 1.58E+06 - - - 3.0025 0.9999 221125_WJC_METTL3_EV_vs_WT_F05.11757.11757.2 0.000199 22-Sep K.GIVEFASKPAAR.K sp|P23246|SFPQ_HUMAN 1 1244.6877 0.78 63897 11757 2 1244.687165 623.3511 "Splicing factor, proline- and glutamine-rich OS=Homo sapiens OX=9606 GN=SFPQ PE=1 SV=2" 8.75 2316.2 - 235389 - - - -0.4467 - 2.177 0.503 - 370.1 1 2 0 -0.0006 12 0 0 0 1.81E+06 2.31E+06 - - - 4.8029 1 221125_WJC_METTL3_EV_vs_WT_F05.11762.11762.3 9.05E-07 16/40 K.NFYQEHPDLAR[166.11].R "sp|P17844|DDX5_HUMAN,tr|J3QR02|J3QR02_HUMAN,tr|X6RLV5|X6RLV5_HUMAN,tr|A0A7I2V507|A0A7I2V507_HUMAN,tr|J3KTA4|J3KTA4_HUMAN,tr|J3KTQ4|J3KTQ4_HUMAN,tr|A0A7I2V2S0|A0A7I2V2S0_HUMAN,tr|J3QRQ7|J3QRQ7_HUMAN" 8 1398.6556 1.65 63901 11762 3 1398.657554 467.2258 Probable ATP-dependent RNA helicase DDX5 OS=Homo sapiens OX=9606 GN=DDX5 PE=1 SV=1 5.32 2316.8 - 5.77E+06 - - - 1.4092 - 2.293 0.549 - 472.5 1 2 0 0.002 11 0 0 0 1.49E+08 9.05E+07 - - - 7.0178 0.9999 221125_WJC_METTL3_EV_vs_WT_F05.11767.11767.2 1.60E-07 22-Dec K.ASTSDYQVISDR.Q sp|Q8NFH5|NUP35_HUMAN 1 1340.6208 2.54 63906 11767 2 1340.619567 671.3177 Nucleoporin NUP35 OS=Homo sapiens OX=9606 GN=NUP35 PE=1 SV=1 4.21 2317.3 - 624916 - - - -0.9376 - 2.386 0.565 - 794.2 1 2 0 -0.0013 12 0 0 0 4.94E+07 1.95E+07 - - - 5.5018 0.9999 221125_WJC_METTL3_EV_vs_WT_F05.11770.11770.3 0.0656 17/52 K.VVEVLAGHGHLYSR.L sp|P49327|FAS_HUMAN 1 1535.8209 0.27 63909 11770 3 1535.823097 512.9476 Fatty acid synthase OS=Homo sapiens OX=9606 GN=FASN PE=1 SV=3 6.89 2317.6 - 454616 - - - 1.4559 - 2.976 0.43 - 484.5 1 2 0 0.0022 14 0 0 0 1.77E+06 6.58E+06 - - - 6.2317 0.9998 221125_WJC_METTL3_EV_vs_WT_F05.11771.11771.2 4.12E-07 20-Oct K.C[160.03]PLC[160.03]QESNFTR.Q "sp|Q8WVD3|RN138_HUMAN,tr|J3QLQ3|J3QLQ3_HUMAN" 2 1410.602 1.61 63910 11771 2 1410.60446 706.3083 E3 ubiquitin-protein ligase RNF138 OS=Homo sapiens OX=9606 GN=RNF138 PE=1 SV=1 5.99 2317.8 - 451023 - - - 1.7298 - 2.204 0.579 - 399.5 1 2 0 0.0024 11 0 0 0 5.81E+06 3.61E+06 - - - 5.4546 0.9985 221125_WJC_METTL3_EV_vs_WT_F05.11772.11772.3 0.0226 Nov-48 K.NPLPPSVGVVDKK.E sp|Q8NC51|PAIRB_HUMAN 1 1348.7715 0.61 63911 11772 3 1348.772987 450.5978 Plasminogen activator inhibitor 1 RNA-binding protein OS=Homo sapiens OX=9606 GN=SERBP1 PE=1 SV=2 8.59 2317.9 - 426857 - - - 1.1388 - 1.863 0.261 - 133.5 1 2 0 0.0015 13 0 0 0 3.25E+06 5.29E+06 - - - 3.1364 0.9999 221125_WJC_METTL3_EV_vs_WT_F05.11773.11773.2 3.23E-07 22-Dec K.ASTSDYQVISDR[166.11].Q sp|Q8NFH5|NUP35_HUMAN 1 1350.6291 2.54 63912 11773 2 1350.630306 676.3218 Nucleoporin NUP35 OS=Homo sapiens OX=9606 GN=NUP35 PE=1 SV=1 4.21 2318 - 407997 - - - 0.8974 - 2.387 0.556 - 694.6 1 2 0 0.0012 12 0 0 0 4.94E+07 1.95E+07 - - - 5.4365 0.9999 221125_WJC_METTL3_EV_vs_WT_F05.11774.11774.3 3.85E-08 16/52 R.AIAGNDDVK[136.11]DAIVR[166.11].A "sp|Q6NXE6|ARMC6_HUMAN,tr|H0YGQ5|H0YGQ5_HUMAN,tr|B4E1N1|B4E1N1_HUMAN,tr|H0YH65|H0YH65_HUMAN" 4 1473.7906 1.21 63913 11774 3 1473.791802 492.2708 Armadillo repeat-containing protein 6 OS=Homo sapiens OX=9606 GN=ARMC6 PE=1 SV=2 4.43 2318.1 - 377608 - - - 0.7973 - 3.004 0.527 - 324.6 1 2 1 0.0012 14 0 0 0 3.97E+06 3.29E+06 - - - 7.3383 1 221125_WJC_METTL3_EV_vs_WT_F05.11783.11783.2 7.69E-07 15/26 F.SGGGFGGGGFGGGR.F sp|P35908|K22E_HUMAN 1 1125.4952 283.06 63920 11783 2 1125.496144 563.7549 "Keratin, type II cytoskeletal 2 epidermal OS=Homo sapiens OX=9606 GN=KRT2 PE=1 SV=2" 9.47 2319.2 - 2.12E+06 - - - 0.8663 - 2.84 0.625 - 620.1 1 1 0 0.001 14 0 0 0 3.15E+07 1.11E+05 - - - 6.2763 0.9997 221125_WJC_METTL3_EV_vs_WT_F05.11785.11785.3 0.00313 13/44 K.GIVEFASKPAAR.K sp|P23246|SFPQ_HUMAN 1 1244.6877 2.71 63922 11785 3 1244.688535 415.9032 "Splicing factor, proline- and glutamine-rich OS=Homo sapiens OX=9606 GN=SFPQ PE=1 SV=2" 8.75 2319.3 - 1.79E+06 - - - 0.654 - 2.312 0.307 - 208.4 1 2 0 0.0008 12 0 0 0 2.99E+07 1.11E+07 - - - 4.2856 0.9449 221125_WJC_METTL3_EV_vs_WT_F05.11786.11786.2 0.0103 12-Jul V.MPSHFSR[166.11].G "sp|P39019|RS19_HUMAN,tr|A0A075B6E2|A0A075B6E2_HUMAN" 2 870.4046 1.1 63923 11786 2 870.404404 436.2096 40S ribosomal protein S19 OS=Homo sapiens OX=9606 GN=RPS19 PE=1 SV=2 9.52 2319.4 - 1.31E+06 - - - -0.1988 - 1.438 0.298 - 217.1 1 1 0 -0.0002 7 0 0 0 1.55E+07 1.41E+07 - - - 2.393 0.9997 221125_WJC_METTL3_EV_vs_WT_F05.11788.11788.3 0.00118 Dec-44 K.GIVEFASK[136.11]PAAR[166.11].K sp|P23246|SFPQ_HUMAN 1 1262.7102 2.71 63925 11788 3 1262.713076 421.9107 "Splicing factor, proline- and glutamine-rich OS=Homo sapiens OX=9606 GN=SFPQ PE=1 SV=2" 8.75 2319.6 - 1.16E+06 - - - 2.2848 - 2.049 0.407 - 176.5 1 2 0 0.0029 12 0 0 0 2.99E+07 1.11E+07 - - - 5.0652 0.9995 221125_WJC_METTL3_EV_vs_WT_F05.11789.11789.2 3.59E-05 20-Jul K.NFYQEHPDLAR.R "sp|P17844|DDX5_HUMAN,tr|J3QR02|J3QR02_HUMAN,tr|X6RLV5|X6RLV5_HUMAN,tr|A0A7I2V507|A0A7I2V507_HUMAN,tr|J3KTA4|J3KTA4_HUMAN,tr|J3KTQ4|J3KTQ4_HUMAN,tr|A0A7I2V2S0|A0A7I2V2S0_HUMAN,tr|J3QRQ7|J3QRQ7_HUMAN" 8 1388.6473 1.41 63926 11789 2 1388.651102 695.3309 Probable ATP-dependent RNA helicase DDX5 OS=Homo sapiens OX=9606 GN=DDX5 PE=1 SV=1 5.32 2319.6 - 959146 - - - 2.7286 - 1.914 0.535 - 177.8 1 2 0 0.0038 11 0 0 0 7.09E+06 5.05E+06 - - - 4.7475 1 221125_WJC_METTL3_EV_vs_WT_F05.11790.11790.2 3.67E-10 13/20 K.NFYQEHPDLAR[166.11].R "sp|P17844|DDX5_HUMAN,tr|J3QR02|J3QR02_HUMAN,tr|X6RLV5|X6RLV5_HUMAN,tr|A0A7I2V507|A0A7I2V507_HUMAN,tr|J3KTA4|J3KTA4_HUMAN,tr|J3KTQ4|J3KTQ4_HUMAN,tr|A0A7I2V2S0|A0A7I2V2S0_HUMAN,tr|J3QRQ7|J3QRQ7_HUMAN" 8 1398.6556 1.41 63927 11790 2 1398.656547 700.3351 Probable ATP-dependent RNA helicase DDX5 OS=Homo sapiens OX=9606 GN=DDX5 PE=1 SV=1 5.32 2319.8 - 766452 - - - 0.6892 - 2.467 0.638 - 747.3 1 2 0 0.001 11 0 0 0 7.09E+06 5.05E+06 - - - 6.1958 0.9997 221125_WJC_METTL3_EV_vs_WT_F05.11791.11791.3 0.00411 Sep-40 R.DPHLAC[160.03]VAYER[166.11].G "sp|Q00610|CLH1_HUMAN,sp|P53675|CLH2_HUMAN,tr|A0A087WVQ6|A0A087WVQ6_HUMAN,tr|A0A087WX41|A0A087WX41_HUMAN" 4 1339.6218 1.37 63928 11791 3 1339.621825 447.5479 Clathrin heavy chain 1 OS=Homo sapiens OX=9606 GN=CLTC PE=1 SV=5 5.32 2319.9 - 673407 - - - -0.0112 - 1.745 0.361 - 191.5 1 2 0 0 11 0 0 0 6.56E+06 4.78E+06 - - - 4.1464 1 221125_WJC_METTL3_EV_vs_WT_F05.11792.11792.2 1.01E-07 20-Nov K.C[160.03]PLC[160.03]QESNFTR[166.11].Q "sp|Q8WVD3|RN138_HUMAN,tr|J3QLQ3|J3QLQ3_HUMAN" 2 1420.6103 1.61 63929 11792 2 1420.611331 711.3124 E3 ubiquitin-protein ligase RNF138 OS=Homo sapiens OX=9606 GN=RNF138 PE=1 SV=1 5.99 2320 - 630442 - - - 0.7328 - 2.435 0.653 - 523.1 1 2 0 0.001 11 0 0 0 5.81E+06 3.61E+06 - - - 6.2712 0.9978 221125_WJC_METTL3_EV_vs_WT_F05.11793.11793.3 0.00693 Nov-40 R.DPHLAC[160.03]VAYER.G "sp|Q00610|CLH1_HUMAN,sp|P53675|CLH2_HUMAN,tr|A0A087WVQ6|A0A087WVQ6_HUMAN,tr|A0A087WX41|A0A087WX41_HUMAN" 4 1329.6136 1.38 63930 11793 3 1329.613051 444.2118 Clathrin heavy chain 1 OS=Homo sapiens OX=9606 GN=CLTC PE=1 SV=5 5.32 2320.1 - 592511 - - - -0.3903 - 1.782 0.233 - 203.9 1 2 0 -0.0005 11 0 0 0 6.62E+06 4.78E+06 - - - 2.7788 0.9961 221125_WJC_METTL3_EV_vs_WT_F05.11794.11794.3 0.458 Nov-52 R.NALQQENHIIDGVK[136.11].V "sp|Q9GZT3|SLIRP_HUMAN,tr|H0YJW7|H0YJW7_HUMAN,tr|A0A087WUN7|A0A087WUN7_HUMAN,tr|G3V2S9|G3V2S9_HUMAN,tr|H0YJ40|H0YJ40_HUMAN,tr|G3V4X6|G3V4X6_HUMAN" 6 1585.8304 0.36 63931 11794 3 1585.829587 529.6174 "SRA stem-loop-interacting RNA-binding protein, mitochondrial OS=Homo sapiens OX=9606 GN=SLIRP PE=1 SV=1" 5.32 2320.2 - 465597 - - - -0.4931 - 1.875 0.195 - 189.5 1 2 0 -0.0008 14 0 0 0 3.53E+06 9.89E+06 - - - 2.3844 0.9763 221125_WJC_METTL3_EV_vs_WT_F05.11795.11795.2 0.00603 20-Nov K.QVQQPSVAQLR[166.11].S "sp|Q15007|FL2D_HUMAN,tr|A0A087X1R4|A0A087X1R4_HUMAN" 2 1262.6971 0.36 63932 11795 2 1262.706262 632.3558 Pre-mRNA-splicing regulator WTAP OS=Homo sapiens OX=9606 GN=WTAP PE=1 SV=2 9.75 2320.3 - 457318 - - - 7.2923 - 1.828 0.393 - 228.2 1 2 0 0.0092 11 0 0 0 1.25E+07 3.48E+07 - - - 3.5727 0.9988 221125_WJC_METTL3_EV_vs_WT_F05.11796.11796.3 0.0159 Nov-40 K.C[160.03]DLVLDAAHEK.S "sp|Q99700|ATX2_HUMAN,tr|A0A5F9ZHW5|A0A5F9ZHW5_HUMAN,tr|A0A5F9ZHH4|A0A5F9ZHH4_HUMAN,tr|A0A5F9ZI57|A0A5F9ZI57_HUMAN,tr|A0A2R8YDM9|A0A2R8YDM9_HUMAN,tr|F8VQP2|F8VQP2_HUMAN,tr|A0A2R8Y5A6|A0A2R8Y5A6_HUMAN,tr|F8WB06|F8WB06_HUMAN,tr|A0A5F9ZH85|A0A5F9ZH85_HUMAN,tr|V9GY86|V9GY86_HUMAN,tr|A0A2R8Y7E6|A0A2R8Y7E6_HUMAN,tr|A0A5F9ZHX3|A0A5F9ZHX3_HUMAN,tr|H0YH87|H0YH87_HUMAN,tr|A0A2R8Y7P6|A0A2R8Y7P6_HUMAN" 14 1269.6023 0.56 63933 11796 3 1269.60049 424.2081 Ataxin-2 OS=Homo sapiens OX=9606 GN=ATXN2 PE=1 SV=2 4.54 2320.4 - 670348 - - - -1.4548 - 1.765 0.288 - 155.1 1 2 0 -0.0018 11 0 0 0 1.44E+06 2.56E+06 - - - 3.3644 0.9703 221125_WJC_METTL3_EV_vs_WT_F05.11797.11797.3 6.48E-05 Dec-40 A.SWADIASKPAK.Q sp|Q9Y5A9|YTHD2_HUMAN 1 1172.619 0.61 63934 11797 3 1172.619154 391.8803 YTH domain-containing family protein 2 OS=Homo sapiens OX=9606 GN=YTHDF2 PE=1 SV=2 8.31 2320.5 - 338440 - - - 0.1544 - 2.282 0.302 - 181.5 1 1 0 0.0002 11 0 0 0 6.56E+06 1.07E+07 - - - 4.2508 1 221125_WJC_METTL3_EV_vs_WT_F05.11798.11798.2 1.87E-06 13/20 R.TSGAFVYDC[160.03]SK[136.11].F sp|Q12948|FOXC1_HUMAN 1 1241.5478 1.99 63935 11798 2 1241.548221 621.7812 Forkhead box protein C1 OS=Homo sapiens OX=9606 GN=FOXC1 PE=1 SV=3 5.5 2320.7 - 271131 - - - 0.348 - 2.685 0.599 - 887.3 1 2 0 0.0004 11 0 0 0 8.32E+06 4.17E+06 - - - 6.137 0.9823 221125_WJC_METTL3_EV_vs_WT_F05.11802.11802.2 0.00182 24-Jul K.VEITYTPSDGTQK.V sp|O75874|IDHC_HUMAN 1 1437.6987 2.29 63939 11802 2 1437.706615 719.8566 Isocitrate dehydrogenase [NADP] cytoplasmic OS=Homo sapiens OX=9606 GN=IDH1 PE=1 SV=2 4.37 2321.2 - 166575 - - - 5.4775 - 1.78 0.304 - 147.8 1 2 0 0.0079 13 0 0 0 1.55E+07 6.79E+06 - - - 2.7638 1 221125_WJC_METTL3_EV_vs_WT_F05.11804.11804.3 1.02E-05 13/48 K.QVK[136.11]PLPAPLDGQR[166.11].K "sp|Q8WWY3|PRP31_HUMAN,tr|E7EVX8|E7EVX8_HUMAN" 2 1435.8266 2.29 63940 11804 3 1435.827099 479.6161 U4\U6 small nuclear ribonucleoprotein Prp31 OS=Homo sapiens OX=9606 GN=PRPF31 PE=1 SV=2 8.75 2321.5 - 3.35E+06 - - - 0.335 - 2.379 0.5 - 275.5 1 2 0 0.0005 13 0 0 0 1.58E+08 6.87E+07 - - - 6.4642 1 221125_WJC_METTL3_EV_vs_WT_F05.11805.11805.3 1.74E-10 14/44 R.TAAENEFVTLKK.D "sp|P48668|K2C6C_HUMAN,sp|P12035|K2C3_HUMAN,sp|P04259|K2C6B_HUMAN,sp|P02538|K2C6A_HUMAN" 4 1349.7191 13980.69 63941 11805 3 1349.719154 450.9136 "Keratin, type II cytoskeletal 6C OS=Homo sapiens OX=9606 GN=KRT6C PE=1 SV=3" 5.81 2321.5 - 9.22E+06 - - - 0.0541 - 2.901 0.533 - 268.4 1 2 0 0.0001 12 0 0 0 6.59E+09 4.71E+05 - - - 7.4346 1 221125_WJC_METTL3_EV_vs_WT_F05.11806.11806.2 1.35E-08 13/20 K.C[160.03]NTDDTIGDLK.K sp|Q9BZL1|UBL5_HUMAN 1 1250.5449 1.91 63942 11806 2 1250.54489 626.2797 Ubiquitin-like protein 5 OS=Homo sapiens OX=9606 GN=UBL5 PE=1 SV=1 3.93 2321.6 - 1.09E+06 - - - 0.0064 - 2.488 0.629 - 836 1 2 0 0 11 0 0 0 8.61E+07 4.51E+07 - - - 6.1526 1 221125_WJC_METTL3_EV_vs_WT_F05.11807.11807.2 4.69E-05 13/26 R.QAVTNPNNTFYATK[136.11].R "sp|P38646|GRP75_HUMAN,tr|H0Y8K0|H0Y8K0_HUMAN,tr|A0A7I2V2S7|A0A7I2V2S7_HUMAN,tr|A0A7I2V2G2|A0A7I2V2G2_HUMAN,tr|A0A3B3ITI4|A0A3B3ITI4_HUMAN,tr|A0A7I2V3F7|A0A7I2V3F7_HUMAN,tr|A0A7I2YQB2|A0A7I2YQB2_HUMAN,tr|D6RCD7|D6RCD7_HUMAN" 8 1575.7773 0.45 63943 11807 2 1575.776927 788.8959 "Stress-70 protein, mitochondrial OS=Homo sapiens OX=9606 GN=HSPA9 PE=1 SV=2" 8.59 2321.8 - 825108 - - - -0.2183 - 2.963 0.553 - 567.4 1 2 0 -0.0003 14 0 0 0 4.91E+08 1.09E+09 - - - 5.8511 0.9999 221125_WJC_METTL3_EV_vs_WT_F05.11808.11808.3 5.78E-06 13/40 R.GYDRYEDYDYR.Y sp|Q13595|TRA2A_HUMAN 1 1513.611 1.8 63944 11808 3 1513.611236 505.5443 Transformer-2 protein homolog alpha OS=Homo sapiens OX=9606 GN=TRA2A PE=1 SV=1 4.23 2321.9 - 734381 - - - 0.1645 - 2.118 0.61 - 191.6 1 2 1 0.0002 11 0 0 0 4.35E+06 2.41E+06 - - - 7.4728 0.9943 221125_WJC_METTL3_EV_vs_WT_F05.11809.11809.3 0.000252 13/40 A.SWADIASK[136.11]PAK[136.11].Q sp|Q9Y5A9|YTHD2_HUMAN 1 1188.6474 0.61 63945 11809 3 1188.647883 397.2231 YTH domain-containing family protein 2 OS=Homo sapiens OX=9606 GN=YTHDF2 PE=1 SV=2 8.31 2322 - 571492 - - - 0.4291 - 2.243 0.446 - 215 1 1 0 0.0005 11 0 0 0 6.56E+06 1.07E+07 - - - 5.8072 0.9963 221125_WJC_METTL3_EV_vs_WT_F05.11810.11810.2 0.00127 20-Nov K.LQLLEDDKENR.Y "sp|P09874|PARP1_HUMAN,tr|A0A7I2V3E1|A0A7I2V3E1_HUMAN" 2 1371.6994 0.75 63946 11810 2 1371.702501 686.857 Poly [ADP-ribose] polymerase 1 OS=Homo sapiens OX=9606 GN=PARP1 PE=1 SV=4 4.32 2322.2 - 405519 - - - 2.2549 - 2.263 0.489 - 522.3 1 2 1 0.0031 11 0 0 0 1.71E+07 2.30E+07 - - - 4.8611 0.9999 221125_WJC_METTL3_EV_vs_WT_F05.11811.11811.2 2.86E-06 26-Nov R.SSFYPDGGDQETAK.T "sp|Q9NYF8|BCLF1_HUMAN,tr|H0YF00|H0YF00_HUMAN,tr|E9PKI6|E9PKI6_HUMAN,tr|A0A1W2PQ43|A0A1W2PQ43_HUMAN,tr|E9PK91|E9PK91_HUMAN,tr|E9PJA7|E9PJA7_HUMAN,tr|E9PK09|E9PK09_HUMAN,tr|E9PQN2|E9PQN2_HUMAN" 8 1500.6369 2.56 63947 11811 2 1500.63548 751.3257 Bcl-2-associated transcription factor 1 OS=Homo sapiens OX=9606 GN=BCLAF1 PE=1 SV=2 4.03 2322.3 - 349674 - - - -0.9249 - 1.818 0.625 - 232.4 1 2 0 -0.0014 14 0 0 0 1.82E+07 7.10E+06 - - - 5.1568 0.9402 221125_WJC_METTL3_EV_vs_WT_F05.11812.11812.3 0.469 Aug-48 K.NPLPPSVGVVDK[136.11]K[136.11].E sp|Q8NC51|PAIRB_HUMAN 1 1364.7999 0.62 63948 11812 3 1364.799504 455.9406 Plasminogen activator inhibitor 1 RNA-binding protein OS=Homo sapiens OX=9606 GN=SERBP1 PE=1 SV=2 8.59 2322.4 - 348010 - - - -0.2542 - 1.555 0.116 - 72.7 4 2 0 -0.0003 13 0 0 0 4.66E+06 7.49E+06 - - - 0.7515 0.9998 221125_WJC_METTL3_EV_vs_WT_F05.11814.11814.3 0.00119 Oct-36 K.EQAQPPHLWK.S sp|P31271|HXA13_HUMAN 1 1232.6302 1.9 63950 11814 3 1232.628334 411.884 Homeobox protein Hox-A13 OS=Homo sapiens OX=9606 GN=HOXA13 PE=1 SV=3 6.85 2322.7 - 314144 - - - -1.5187 - 1.867 0.391 - 211 1 2 0 -0.0019 10 0 0 0 1.05E+07 5.55E+06 - - - 4.7221 1 221125_WJC_METTL3_EV_vs_WT_F05.11815.11815.2 9.64E-07 14/26 K.EIQTTTGNQQVLVR[166.11].K sp|Q8TC12|RDH11_HUMAN 1 1595.8507 0.83 63951 11815 2 1595.851737 798.9326 Retinol dehydrogenase 11 OS=Homo sapiens OX=9606 GN=RDH11 PE=1 SV=2 6.1 2322.8 - 173999 - - - 0.6786 - 2.835 0.571 - 898.9 1 2 0 0.0011 14 0 0 0 1.35E+07 1.62E+07 - - - 5.873 0.9997 221125_WJC_METTL3_EV_vs_WT_F05.11820.11820.2 0.00578 22-Sep R.TAAENEFVTLKK.D "sp|P48668|K2C6C_HUMAN,sp|P12035|K2C3_HUMAN,sp|P04259|K2C6B_HUMAN,sp|P02538|K2C6A_HUMAN" 4 1349.7191 999 63954 11820 2 1349.719608 675.8668 "Keratin, type II cytoskeletal 6C OS=Homo sapiens OX=9606 GN=KRT6C PE=1 SV=3" 5.81 2323.4 - 3.67E+06 - - - 0.3905 - 1.885 0.394 - 225.5 1 2 0 0.0005 12 0 0 0 6.55E+08 0.00E+00 - - - 3.6189 0.9999 221125_WJC_METTL3_EV_vs_WT_F05.11821.11821.3 0.000291 13/40 K.C[160.03]EAIITHFNGK.Y "sp|Q15434|RBMS2_HUMAN,tr|F8VV01|F8VV01_HUMAN,tr|F5H5C8|F5H5C8_HUMAN,tr|F8W1T6|F8W1T6_HUMAN" 4 1288.6234 1.48 63955 11821 3 1288.622766 430.5484 "RNA-binding motif, single-stranded-interacting protein 2 OS=Homo sapiens OX=9606 GN=RBMS2 PE=1 SV=1" 6.74 2323.5 - 1.80E+06 - - - -0.4974 - 2.446 0.369 - 397 1 2 0 -0.0006 11 0 0 0 1.26E+07 8.54E+06 - - - 5.1948 1 221125_WJC_METTL3_EV_vs_WT_F05.11823.11823.2 5.13E-09 16/26 R.QAVTNPNNTFYATK.R "sp|P38646|GRP75_HUMAN,tr|H0Y8K0|H0Y8K0_HUMAN,tr|A0A7I2V2S7|A0A7I2V2S7_HUMAN,tr|A0A7I2V2G2|A0A7I2V2G2_HUMAN,tr|A0A3B3ITI4|A0A3B3ITI4_HUMAN,tr|A0A7I2V3F7|A0A7I2V3F7_HUMAN,tr|A0A7I2YQB2|A0A7I2YQB2_HUMAN,tr|D6RCD7|D6RCD7_HUMAN" 8 1567.7631 0.45 63957 11823 2 1567.763081 784.8888 "Stress-70 protein, mitochondrial OS=Homo sapiens OX=9606 GN=HSPA9 PE=1 SV=2" 8.59 2323.6 - 1.33E+06 - - - 0.0064 - 3.243 0.606 - 929.9 1 2 0 0 14 0 0 0 4.90E+08 1.08E+09 - - - 6.4693 0.9932 221125_WJC_METTL3_EV_vs_WT_F05.11824.11824.2 1.50E-06 18-Dec A.AENEFVTLKK.D "sp|P48668|K2C6C_HUMAN,sp|P12035|K2C3_HUMAN,sp|P04264|K2C1_HUMAN,sp|P04259|K2C6B_HUMAN,sp|P02538|K2C6A_HUMAN" 5 1177.6343 999 63958 11824 2 1177.63502 589.8244 "Keratin, type II cytoskeletal 6C OS=Homo sapiens OX=9606 GN=KRT6C PE=1 SV=3" 6.19 2323.7 - 1.16E+06 - - - 0.6207 - 2.569 0.481 - 612 1 1 0 0.0007 10 0 0 0 1.55E+08 0.00E+00 - - - 5.2271 0.9971 221125_WJC_METTL3_EV_vs_WT_F05.11826.11826.2 0.0114 20-Nov K.LQLLEDDK[136.11]ENR[166.11].Y "sp|P09874|PARP1_HUMAN,tr|A0A7I2V3E1|A0A7I2V3E1_HUMAN" 2 1389.7219 0.75 63960 11826 2 1389.72207 695.8682 Poly [ADP-ribose] polymerase 1 OS=Homo sapiens OX=9606 GN=PARP1 PE=1 SV=4 4.32 2323.9 - 1.06E+06 - - - 0.1382 - 2.229 0.347 - 534.9 1 2 1 0.0002 11 0 0 0 1.71E+07 2.30E+07 - - - 3.7723 0.9931 221125_WJC_METTL3_EV_vs_WT_F05.11827.11827.2 0.0216 14-Aug K.DVESYIHR[166.11].S "sp|Q9NR30|DDX21_HUMAN,sp|Q9BQ39|DDX50_HUMAN" 2 1027.4962 0.9 63961 11827 2 1027.495809 514.7554 Nucleolar RNA helicase 2 OS=Homo sapiens OX=9606 GN=DDX21 PE=1 SV=5 5.32 2324.1 - 846143 - - - -0.4088 - 1.489 0.087 - 252.3 1 2 0 -0.0004 8 0 0 0 5.91E+06 6.58E+06 - - - 0.8841 0.9998 221125_WJC_METTL3_EV_vs_WT_F05.11829.11829.3 4.66E-05 Oct-52 K.EIQTTTGNQQVLVR[166.11].K sp|Q8TC12|RDH11_HUMAN 1 1595.8507 5 63963 11829 3 1595.849267 532.9575 Retinol dehydrogenase 11 OS=Homo sapiens OX=9606 GN=RDH11 PE=1 SV=2 6.1 2324.3 - 508086 - - - -0.8691 - 1.861 0.405 - 162.6 1 2 0 -0.0014 14 0 0 0 3.29E+07 6.57E+06 - - - 4.7056 0.9985 221125_WJC_METTL3_EV_vs_WT_F05.11831.11831.2 1.72E-06 24-Nov K.VEITYTPSDGTQK[136.11].V sp|O75874|IDHC_HUMAN 1 1445.7129 2.29 63965 11831 2 1445.719527 723.8637 Isocitrate dehydrogenase [NADP] cytoplasmic OS=Homo sapiens OX=9606 GN=IDH1 PE=1 SV=2 4.37 2324.6 - 385025 - - - 4.5562 - 2.178 0.559 - 343.8 1 2 0 0.0066 13 0 0 0 1.55E+07 6.79E+06 - - - 5.1655 0.9516 221125_WJC_METTL3_EV_vs_WT_F05.11834.11834.3 0.315 Aug-36 K.R[166.11]ANEFLEVGK[136.11].K sp|Q14152|EIF3A_HUMAN 1 1179.6367 0.54 63968 11834 3 1179.632592 394.2195 Eukaryotic translation initiation factor 3 subunit A OS=Homo sapiens OX=9606 GN=EIF3A PE=1 SV=1 6.14 2324.9 - 196084 - - - -3.4756 - 1.453 0.198 - 81.8 1 2 0 -0.0041 10 0 0 0 8.92E+05 1.66E+06 - - - 1.8375 0.9998 221125_WJC_METTL3_EV_vs_WT_F05.11837.11837.3 3.74E-05 14/40 K.LQLLEDDK[136.11]ENR[166.11].Y "sp|P09874|PARP1_HUMAN,tr|A0A7I2V3E1|A0A7I2V3E1_HUMAN" 2 1389.7219 0.93 63969 11837 3 1389.719697 464.2479 Poly [ADP-ribose] polymerase 1 OS=Homo sapiens OX=9606 GN=PARP1 PE=1 SV=4 4.32 2325.4 - 1.52E+07 - - - -1.5694 - 2.587 0.475 - 356.2 1 2 1 -0.0022 11 0 0 0 1.80E+08 1.93E+08 - - - 6.5354 1 221125_WJC_METTL3_EV_vs_WT_F05.11838.11838.3 9.49E-05 18/44 R.LLASTLVHSVK[136.11]K[136.11].E "sp|Q9NYF8|BCLF1_HUMAN,tr|E9PKI6|E9PKI6_HUMAN,tr|A0A1W2PQ43|A0A1W2PQ43_HUMAN,tr|E9PK91|E9PK91_HUMAN,tr|E9PJA7|E9PJA7_HUMAN,tr|E9PK09|E9PK09_HUMAN,tr|E9PQN2|E9PQN2_HUMAN" 7 1310.8257 1.63 63970 11838 3 1310.824541 437.9492 Bcl-2-associated transcription factor 1 OS=Homo sapiens OX=9606 GN=BCLAF1 PE=1 SV=2 10 2325.5 - 1.40E+06 - - - -0.8628 - 3.467 0.478 - 535.5 1 2 0 -0.0011 12 0 0 0 3.99E+08 2.44E+08 - - - 7.3151 0.9344 221125_WJC_METTL3_EV_vs_WT_F05.11839.11839.2 0.0139 16-Sep A.ENEFVTLKK.D "sp|P48668|K2C6C_HUMAN,sp|P12035|K2C3_HUMAN,sp|P04264|K2C1_HUMAN,sp|P04259|K2C6B_HUMAN,sp|P02538|K2C6A_HUMAN" 5 1106.5972 999 63971 11839 2 1106.595553 554.3059 "Keratin, type II cytoskeletal 6C OS=Homo sapiens OX=9606 GN=KRT6C PE=1 SV=3" 6.24 2325.6 - 672536 - - - -1.4658 - 1.584 0.303 - 340.3 1 1 0 -0.0016 9 0 0 0 1.85E+07 0.00E+00 - - - 2.6091 0.9998 221125_WJC_METTL3_EV_vs_WT_F05.11841.11841.3 0.0251 13/32 K.EEFDLEAHR[166.11].L sp|Q96BN2|TADA1_HUMAN 1 1154.5232 5.98 63973 11841 3 1154.521522 385.8483 Transcriptional adapter 1 OS=Homo sapiens OX=9606 GN=TADA1 PE=1 SV=1 4.4 2325.9 - 427350 - - - -1.4292 - 1.959 0.363 - 271.7 1 2 0 -0.0016 9 0 0 0 2.61E+07 4.38E+06 - - - 4.6132 0.9941 221125_WJC_METTL3_EV_vs_WT_F05.11844.11844.2 0.00788 20-Jul R.RVEIMEEESEQ.- "sp|P54578|UBP14_HUMAN,tr|A6NJA2|A6NJA2_HUMAN" 2 1377.6082 1.3 63976 11844 2 1377.613703 689.8114 Ubiquitin carboxyl-terminal hydrolase 14 OS=Homo sapiens OX=9606 GN=USP14 PE=1 SV=3 3.98 2326.3 - 267899 - - - 3.9873 - 1.533 0.352 - 143.1 1 2 0 0.0055 11 0 0 0 2.78E+06 2.14E+06 - - - 2.7949 0.9998 221125_WJC_METTL3_EV_vs_WT_F05.11845.11845.2 3.82E-06 13/26 R.SLGPPQGEEDSVPR[166.11].D sp|P78527|PRKDC_HUMAN 1 1476.7084 2.64 63977 11845 2 1476.710792 739.3615 DNA-dependent protein kinase catalytic subunit OS=Homo sapiens OX=9606 GN=PRKDC PE=1 SV=3 4.14 2326.4 - 266924 - - - 1.6151 - 2.134 0.569 - 353.5 1 2 0 0.0024 14 0 0 0 1.07E+07 4.06E+06 - - - 5.145 0.9999 221125_WJC_METTL3_EV_vs_WT_F05.11847.11847.3 0.000106 16/44 R.LLASTLVHSVKK.E "sp|Q9NYF8|BCLF1_HUMAN,tr|E9PKI6|E9PKI6_HUMAN,tr|A0A1W2PQ43|A0A1W2PQ43_HUMAN,tr|E9PK91|E9PK91_HUMAN,tr|E9PJA7|E9PJA7_HUMAN,tr|E9PK09|E9PK09_HUMAN,tr|E9PQN2|E9PQN2_HUMAN" 7 1294.7973 1.63 63978 11847 3 1294.800715 432.6064 Bcl-2-associated transcription factor 1 OS=Homo sapiens OX=9606 GN=BCLAF1 PE=1 SV=2 10 2326.6 - 4.21E+06 - - - 2.6591 - 3.176 0.429 - 387.9 1 2 0 0.0034 12 0 0 0 3.99E+08 2.44E+08 - - - 6.5252 0.9998 221125_WJC_METTL3_EV_vs_WT_F05.11851.11851.2 7.51E-06 20-Oct R.QNVAVNELC[160.03]GR.C "sp|Q15942|ZYX_HUMAN,tr|H0Y2Y8|H0Y2Y8_HUMAN,tr|C9JJK5|C9JJK5_HUMAN" 3 1258.6088 5.98 63981 11851 2 1258.607724 630.3117 Zyxin OS=Homo sapiens OX=9606 GN=ZYX PE=1 SV=1 5.99 2326.9 - 3.30E+06 - - - -0.87 - 1.813 0.514 - 406.2 1 2 0 -0.0011 11 0 0 0 4.16E+07 6.95E+06 - - - 4.4466 0.9999 221125_WJC_METTL3_EV_vs_WT_F05.11852.11852.3 0.00192 14/52 R.QAVTNPNNTFYATK[136.11].R "sp|P38646|GRP75_HUMAN,tr|H0Y8K0|H0Y8K0_HUMAN,tr|A0A7I2V2S7|A0A7I2V2S7_HUMAN,tr|A0A7I2V2G2|A0A7I2V2G2_HUMAN,tr|A0A3B3ITI4|A0A3B3ITI4_HUMAN,tr|A0A7I2V3F7|A0A7I2V3F7_HUMAN,tr|A0A7I2YQB2|A0A7I2YQB2_HUMAN,tr|D6RCD7|D6RCD7_HUMAN" 8 1575.7773 0.47 63982 11852 3 1575.774249 526.2664 "Stress-70 protein, mitochondrial OS=Homo sapiens OX=9606 GN=HSPA9 PE=1 SV=2" 8.59 2327 - 2.07E+06 - - - -1.9178 - 2.632 0.436 - 435.2 1 2 0 -0.003 14 0 0 0 2.35E+07 5.03E+07 - - - 5.9719 0.9988 221125_WJC_METTL3_EV_vs_WT_F05.11856.11856.3 0.000413 Oct-40 K.DPLNPIK[136.11]QDVK[136.11].K "sp|Q15181|IPYR_HUMAN,tr|Q5SQT6|Q5SQT6_HUMAN" 2 1281.7264 1.13 63986 11856 3 1281.724983 428.2494 Inorganic pyrophosphatase OS=Homo sapiens OX=9606 GN=PPA1 PE=1 SV=2 5.96 2327.5 - 699208 - - - -1.0681 - 2.092 0.334 - 168.7 1 2 1 -0.0014 11 0 0 0 3.77E+07 3.34E+07 - - - 4.3603 0.9997 221125_WJC_METTL3_EV_vs_WT_F05.11857.11857.3 1.04E-05 Nov-36 K.DK[136.11]GEYTLVVK[136.11].W "sp|P21333|FLNA_HUMAN,tr|A0A7P0NMY4|A0A7P0NMY4_HUMAN,tr|Q60FE5|Q60FE5_HUMAN" 3 1166.6518 2.25 63987 11857 3 1166.650457 389.8912 Filamin-A OS=Homo sapiens OX=9606 GN=FLNA PE=1 SV=4 6.07 2327.6 - 614520 - - - -1.1426 - 2.095 0.449 - 180.4 1 2 1 -0.0013 10 0 0 0 3.19E+07 1.42E+07 - - - 5.7054 1 221125_WJC_METTL3_EV_vs_WT_F05.11858.11858.2 1.24E-07 22-Nov R.TC[160.03]DDDLTEQQLR.S "tr|H0YC81|H0YC81_HUMAN,tr|A0A494BZV7|A0A494BZV7_HUMAN,tr|E5RI93|E5RI93_HUMAN,tr|E7EVZ1|E7EVZ1_HUMAN" 4 1492.6464 1.68 63988 11858 2 1493.653137 747.3305 Zinc finger homeobox protein 4 (Fragment) OS=Homo sapiens OX=9606 GN=ZFHX4 PE=1 SV=1 3.84 2327.7 - 599937 - - - 674.4732 - 2.465 0.697 - 446.9 1 2 0 1.0068 12 0 0 0 9.21E+06 5.49E+06 - - - 6.2467 0.9994 221125_WJC_METTL3_EV_vs_WT_F05.11863.11863.2 2.01E-06 20-Nov K.TTQFSC[160.03]TLGEK.F "sp|Q01469|FABP5_HUMAN,tr|I6L8B7|I6L8B7_HUMAN" 2 1270.5864 192.76 63991 11863 2 1270.581944 636.3005 Fatty acid-binding protein 5 OS=Homo sapiens OX=9606 GN=FABP5 PE=1 SV=3 5.66 2328.2 - 2.75E+06 - - - -3.4701 - 2.196 0.543 - 553.5 1 2 0 -0.0044 11 0 0 0 2.06E+08 1.07E+06 - - - 5.1783 0.9979 221125_WJC_METTL3_EV_vs_WT_F05.11870.11870.3 0.00999 Oct-36 K.DKGEYTLVVK.W "sp|P21333|FLNA_HUMAN,tr|A0A7P0NMY4|A0A7P0NMY4_HUMAN,tr|Q60FE5|Q60FE5_HUMAN" 3 1150.6234 2.25 63996 11870 3 1150.620728 384.5484 Filamin-A OS=Homo sapiens OX=9606 GN=FLNA PE=1 SV=4 6.07 2329.1 - 901125 - - - -2.3135 - 1.961 0.364 - 160.8 1 2 1 -0.0027 10 0 0 0 3.19E+07 1.42E+07 - - - 4.5643 1 221125_WJC_METTL3_EV_vs_WT_F05.11871.11871.2 2.93E-09 15/18 K.DKGEYTLVVK.W "sp|P21333|FLNA_HUMAN,tr|A0A7P0NMY4|A0A7P0NMY4_HUMAN,tr|Q60FE5|Q60FE5_HUMAN" 3 1150.6234 2.92 63997 11871 2 1150.623062 576.319 Filamin-A OS=Homo sapiens OX=9606 GN=FLNA PE=1 SV=4 6.07 2329.2 - 835341 - - - -0.2851 - 2.57 0.586 - 644.2 1 2 1 -0.0003 10 0 0 0 2.30E+07 7.89E+06 - - - 6.0038 1 221125_WJC_METTL3_EV_vs_WT_F05.11872.11872.3 1.57E-09 18/64 R.VMLGETNPADSK[136.11]PGTIR[166.11].G "sp|O60361|NDK8_HUMAN,sp|P15531|NDKA_HUMAN,sp|P22392|NDKB_HUMAN,tr|Q32Q12|Q32Q12_HUMAN,tr|Q32Q12|Q32Q12_HUMAN,tr|J3KPD9|J3KPD9_HUMAN,tr|E7ERL0|E7ERL0_HUMAN" 7 1802.9316 1.47 63998 11872 3 1802.932554 601.9845 Putative nucleoside diphosphate kinase OS=Homo sapiens OX=9606 GN=NME2P1 PE=5 SV=1 6.04 2329.4 - 826896 - - - 0.5547 - 3.46 0.595 - 348.3 1 2 0 0.001 17 0 0 0 9.55E+08 6.48E+08 - - - 8.3092 1 221125_WJC_METTL3_EV_vs_WT_F05.11875.11875.3 6.11E-06 16/44 K.TLLHLGSSAPGK[136.11].E "sp|Q5SW79|CE170_HUMAN,tr|H0Y2V6|H0Y2V6_HUMAN" 2 1187.6754 0.91 64001 11875 3 1187.674021 396.8991 Centrosomal protein of 170 kDa OS=Homo sapiens OX=9606 GN=CEP170 PE=1 SV=1 8.44 2329.7 - 379249 - - - -1.1375 - 2.685 0.499 - 325.1 1 2 0 -0.0014 12 0 0 0 1.33E+07 1.46E+07 - - - 6.8407 0.9991 221125_WJC_METTL3_EV_vs_WT_F05.11879.11879.2 5.14E-05 20-Sep K.C[160.03]NTDDTIGDLK[136.11].K sp|Q9BZL1|UBL5_HUMAN 1 1258.5591 1.9 64003 11879 2 1258.555566 630.2868 Ubiquitin-like protein 5 OS=Homo sapiens OX=9606 GN=UBL5 PE=1 SV=1 3.93 2330.2 - 2.54E+06 - - - -2.7937 - 1.637 0.479 - 297 1 2 0 -0.0035 11 0 0 0 8.61E+07 4.52E+07 - - - 3.9111 0.9996 221125_WJC_METTL3_EV_vs_WT_F05.11880.11880.2 9.56E-06 20-Nov K.GNDPNVNIVPK.D "sp|Q9Y520|PRC2C_HUMAN,tr|E7EPN9|E7EPN9_HUMAN" 2 1165.6091 1.31 64004 11880 2 1165.606275 583.8118 Protein PRRC2C OS=Homo sapiens OX=9606 GN=PRRC2C PE=1 SV=4 5.84 2330.3 - 1.77E+06 - - - -2.4554 - 1.995 0.504 - 392.2 1 2 0 -0.0029 11 0 0 0 7.22E+07 5.52E+07 - - - 4.631 1 221125_WJC_METTL3_EV_vs_WT_F05.11881.11881.3 3.13E-05 14/52 R.QAVTNPNNTFYATK.R "sp|P38646|GRP75_HUMAN,tr|H0Y8K0|H0Y8K0_HUMAN,tr|A0A7I2V2S7|A0A7I2V2S7_HUMAN,tr|A0A7I2V2G2|A0A7I2V2G2_HUMAN,tr|A0A3B3ITI4|A0A3B3ITI4_HUMAN,tr|A0A7I2V3F7|A0A7I2V3F7_HUMAN,tr|A0A7I2YQB2|A0A7I2YQB2_HUMAN,tr|D6RCD7|D6RCD7_HUMAN" 8 1567.7631 0.46 64005 11881 3 1567.761268 523.595 "Stress-70 protein, mitochondrial OS=Homo sapiens OX=9606 GN=HSPA9 PE=1 SV=2" 8.59 2330.4 - 1.33E+06 - - - -1.15 - 2.717 0.476 - 348.9 1 2 0 -0.0018 14 0 0 0 2.35E+07 5.06E+07 - - - 6.5027 0.9999 221125_WJC_METTL3_EV_vs_WT_F05.11888.11888.3 6.21E-05 16/48 R.VETLREEAPTDLR.V sp|Q9NW68|BSDC1_HUMAN 1 1527.7893 1.67 64011 11888 3 1527.787758 510.2704 BSD domain-containing protein 1 OS=Homo sapiens OX=9606 GN=BSDC1 PE=1 SV=1 4.41 2331.4 - 1.42E+06 - - - -1.0001 - 2.704 0.466 - 333.5 1 2 1 -0.0015 13 0 0 0 3.41E+07 2.04E+07 - - - 6.432 1 221125_WJC_METTL3_EV_vs_WT_F05.11894.11894.3 6.25E-06 14/56 R.IRPTVQEDGGDVIYK.G "sp|Q9UMS0|NFU1_HUMAN,tr|C9J8Q1|C9J8Q1_HUMAN,tr|F8W9P7|F8W9P7_HUMAN,tr|H7C537|H7C537_HUMAN" 4 1688.8734 1.37 64016 11894 3 1688.87184 563.9651 "NFU1 iron-sulfur cluster scaffold homolog, mitochondrial OS=Homo sapiens OX=9606 GN=NFU1 PE=1 SV=2" 4.56 2332 - 869540 - - - -0.8941 - 2.951 0.526 - 289.7 1 2 0 -0.0015 15 0 0 0 1.28E+07 9.36E+06 - - - 7.2277 1 221125_WJC_METTL3_EV_vs_WT_F05.11895.11895.3 0.00142 14/44 K.TLLHLGSSAPGK.E "sp|Q5SW79|CE170_HUMAN,tr|H0Y2V6|H0Y2V6_HUMAN" 2 1179.6612 0.91 64017 11895 3 1179.661161 394.2277 Centrosomal protein of 170 kDa OS=Homo sapiens OX=9606 GN=CEP170 PE=1 SV=1 8.44 2332.1 - 703307 - - - -0.0093 - 2.051 0.486 - 241.8 1 2 0 0 12 0 0 0 1.33E+07 1.46E+07 - - - 5.9495 0.9753 221125_WJC_METTL3_EV_vs_WT_F05.11898.11898.2 0.0011 20-Jul K.DPLNPIK[136.11]QDVK[136.11].K "sp|Q15181|IPYR_HUMAN,tr|Q5SQT6|Q5SQT6_HUMAN" 2 1281.7264 3.45 64020 11898 2 1281.721973 641.8705 Inorganic pyrophosphatase OS=Homo sapiens OX=9606 GN=PPA1 PE=1 SV=2 5.96 2332.5 - 356584 - - - -3.4165 - 1.641 0.4 - 252.2 1 2 1 -0.0044 11 0 0 0 1.33E+07 3.86E+06 - - - 3.3339 1 221125_WJC_METTL3_EV_vs_WT_F05.11901.11901.3 2.00E-06 18/64 R.VMLGETNPADSKPGTIR.G "sp|O60361|NDK8_HUMAN,sp|P15531|NDKA_HUMAN,sp|P22392|NDKB_HUMAN,tr|Q32Q12|Q32Q12_HUMAN,tr|Q32Q12|Q32Q12_HUMAN,tr|J3KPD9|J3KPD9_HUMAN,tr|E7ERL0|E7ERL0_HUMAN" 7 1784.9091 1.47 64022 11901 3 1784.907803 595.977 Putative nucleoside diphosphate kinase OS=Homo sapiens OX=9606 GN=NME2P1 PE=5 SV=1 6.04 2332.8 - 5.89E+06 - - - -0.7177 - 3.282 0.61 - 406.9 1 2 0 -0.0013 17 0 0 0 9.55E+08 6.48E+08 - - - 8.3429 0.9478 221125_WJC_METTL3_EV_vs_WT_F05.11902.11902.3 0.0312 13/40 L.LASTLVHSVKK.E "sp|Q9NYF8|BCLF1_HUMAN,tr|E9PKI6|E9PKI6_HUMAN,tr|A0A1W2PQ43|A0A1W2PQ43_HUMAN,tr|E9PK91|E9PK91_HUMAN,tr|E9PJA7|E9PJA7_HUMAN,tr|E9PK09|E9PK09_HUMAN,tr|E9PQN2|E9PQN2_HUMAN" 7 1181.7132 2.4 64023 11902 3 1181.711078 394.9117 Bcl-2-associated transcription factor 1 OS=Homo sapiens OX=9606 GN=BCLAF1 PE=1 SV=2 10 2332.9 - 1.52E+06 - - - -1.8025 - 1.807 0.352 - 145.9 1 1 0 -0.0021 11 0 0 0 2.36E+07 9.82E+06 - - - 4.1447 1 221125_WJC_METTL3_EV_vs_WT_F05.11903.11903.3 1.03E-06 15/56 R.IR[166.11]PTVQEDGGDVIYK[136.11].G "sp|Q9UMS0|NFU1_HUMAN,tr|C9J8Q1|C9J8Q1_HUMAN,tr|F8W9P7|F8W9P7_HUMAN,tr|H7C537|H7C537_HUMAN" 4 1706.8958 1.37 64024 11903 3 1706.891814 569.9725 "NFU1 iron-sulfur cluster scaffold homolog, mitochondrial OS=Homo sapiens OX=9606 GN=NFU1 PE=1 SV=2" 4.56 2333 - 826062 - - - -2.347 - 3.001 0.55 - 417.3 1 2 0 -0.004 15 0 0 0 1.28E+07 9.36E+06 - - - 7.5384 0.9996 221125_WJC_METTL3_EV_vs_WT_F05.11906.11906.3 0.00415 Nov-44 R.LLASTLVHSVK[136.11]K.E "sp|Q9NYF8|BCLF1_HUMAN,tr|E9PKI6|E9PKI6_HUMAN,tr|A0A1W2PQ43|A0A1W2PQ43_HUMAN,tr|E9PK91|E9PK91_HUMAN,tr|E9PJA7|E9PJA7_HUMAN,tr|E9PK09|E9PK09_HUMAN,tr|E9PQN2|E9PQN2_HUMAN" 7 1302.8115 - 64027 11906 3 1302.809619 435.2778 Bcl-2-associated transcription factor 1 OS=Homo sapiens OX=9606 GN=BCLAF1 PE=1 SV=2 10 2333.4 - 381936 - - - -1.4223 - 1.981 0.33 - 96.6 1 2 0 -0.0019 12 0 0 0 - - - - - 4.1135 0.9997 221125_WJC_METTL3_EV_vs_WT_F05.11912.11912.3 0.00871 Dec-40 K.NFYVEHPEVAR.L "sp|Q92841|DDX17_HUMAN,tr|A0A5H1ZRQ2|A0A5H1ZRQ2_HUMAN,tr|A0A1X7SBZ2|A0A1X7SBZ2_HUMAN" 3 1359.6571 1.21 64031 11912 3 1359.654786 454.2263 Probable ATP-dependent RNA helicase DDX17 OS=Homo sapiens OX=9606 GN=DDX17 PE=1 SV=2 5.4 2334 - 873299 - - - -1.7379 - 2.235 0.341 - 187.4 1 2 0 -0.0024 11 0 0 0 1.97E+07 1.62E+07 - - - 4.6259 0.9986 221125_WJC_METTL3_EV_vs_WT_F05.11913.11913.2 1.51E-07 16/22 R.LLASTLVHSVKK.E "sp|Q9NYF8|BCLF1_HUMAN,tr|E9PKI6|E9PKI6_HUMAN,tr|A0A1W2PQ43|A0A1W2PQ43_HUMAN,tr|E9PK91|E9PK91_HUMAN,tr|E9PJA7|E9PJA7_HUMAN,tr|E9PK09|E9PK09_HUMAN,tr|E9PQN2|E9PQN2_HUMAN" 7 1294.7973 1.61 64032 11913 2 1294.803015 648.4059 Bcl-2-associated transcription factor 1 OS=Homo sapiens OX=9606 GN=BCLAF1 PE=1 SV=2 10 2334.1 - 803078 - - - 4.4354 - 2.995 0.433 - 814.1 1 2 0 0.0057 12 0 0 0 2.20E+07 1.37E+07 - - - 5.1236 0.9959 221125_WJC_METTL3_EV_vs_WT_F05.11915.11915.2 0.433 20-Jul R.NTVPSVSSISR[166.11].L sp|P23760|PAX3_HUMAN 1 1155.6123 4.74 64034 11915 2 1155.61038 578.8134 Paired box protein Pax-3 OS=Homo sapiens OX=9606 GN=PAX3 PE=1 SV=2 9.75 2334.4 - 581350 - - - -1.6796 - 1.531 0.228 - 90.6 3 2 0 -0.0019 11 0 0 0 3.81E+07 8.04E+06 - - - 1.6635 0.9995 221125_WJC_METTL3_EV_vs_WT_F05.11916.11916.3 0.000934 Oct-36 R.NR[166.11]EILDESLR[166.11].L sp|Q8WUM4|PDC6I_HUMAN 1 1263.6686 0.6 64035 11916 3 1263.667427 422.2301 Programmed cell death 6-interacting protein OS=Homo sapiens OX=9606 GN=PDCD6IP PE=1 SV=1 4.68 2334.5 - 544122 - - - -0.9314 - 2.304 0.365 - 287.4 1 2 1 -0.0012 10 0 0 0 2.17E+06 3.65E+06 - - - 5.0466 0.8155 221125_WJC_METTL3_EV_vs_WT_F05.11917.11917.3 3.43 13/40 L.LASTLVHSVK[136.11]K[136.11].E "sp|Q9NYF8|BCLF1_HUMAN,tr|E9PKI6|E9PKI6_HUMAN,tr|A0A1W2PQ43|A0A1W2PQ43_HUMAN,tr|E9PK91|E9PK91_HUMAN,tr|E9PJA7|E9PJA7_HUMAN,tr|E9PK09|E9PK09_HUMAN,tr|E9PQN2|E9PQN2_HUMAN" 7 1197.7416 2.37 64036 11917 3 1197.7376 400.2545 Bcl-2-associated transcription factor 1 OS=Homo sapiens OX=9606 GN=BCLAF1 PE=1 SV=2 10 2334.6 - 533798 - - - -3.3463 - 2.497 0.249 - 157.3 1 1 0 -0.004 11 0 0 0 2.36E+07 9.94E+06 - - - 3.9146 0.9959 221125_WJC_METTL3_EV_vs_WT_F05.11918.11918.3 0.0225 Sep-32 K.IKDC[160.03]PWYDR.G "sp|O95639|CPSF4_HUMAN,tr|H7C419|H7C419_HUMAN,tr|C9K0K2|C9K0K2_HUMAN,tr|B7Z7B0|B7Z7B0_HUMAN,tr|H7C016|H7C016_HUMAN" 5 1251.5706 1.44 64037 11918 3 1251.569021 418.1975 Cleavage and polyadenylation specificity factor subunit 4 OS=Homo sapiens OX=9606 GN=CPSF4 PE=1 SV=1 5.95 2334.7 - 317288 - - - -1.296 - 1.751 0.293 - 134.3 1 2 1 -0.0016 9 0 0 0 1.45E+07 1.01E+07 - - - 3.4945 1 221125_WJC_METTL3_EV_vs_WT_F05.11921.11921.3 1.78E-07 Nov-44 R.R[166.11]FDDAVVQSDMK[136.11].H "sp|P11142|HSP7C_HUMAN,tr|E9PQQ4|E9PQQ4_HUMAN,tr|E9PNE6|E9PNE6_HUMAN,tr|E9PKE3|E9PKE3_HUMAN,tr|E9PN89|E9PN89_HUMAN,tr|E9PLF4|E9PLF4_HUMAN,tr|E9PK54|E9PK54_HUMAN,tr|E9PN25|E9PN25_HUMAN,tr|E9PPY6|E9PPY6_HUMAN,tr|E9PQK7|E9PQK7_HUMAN" 10 1427.6834 0.13 64039 11921 3 1427.681251 476.9017 Heat shock cognate 71 kDa protein OS=Homo sapiens OX=9606 GN=HSPA8 PE=1 SV=1 4.43 2335.1 - 5.21E+07 - - - -1.494 - 2.552 0.52 - 232.7 1 2 0 -0.0021 12 0 0 0 3.67E+08 2.81E+09 - - - 6.9338 1 221125_WJC_METTL3_EV_vs_WT_F05.11922.11922.2 4.11E-08 17/22 R.R[166.11]FDDAVVQSDMK[136.11].H "sp|P11142|HSP7C_HUMAN,tr|E9PQQ4|E9PQQ4_HUMAN,tr|E9PNE6|E9PNE6_HUMAN,tr|E9PKE3|E9PKE3_HUMAN,tr|E9PN89|E9PN89_HUMAN,tr|E9PLF4|E9PLF4_HUMAN,tr|E9PK54|E9PK54_HUMAN,tr|E9PN25|E9PN25_HUMAN,tr|E9PPY6|E9PPY6_HUMAN,tr|E9PQK7|E9PQK7_HUMAN" 10 1427.6834 0.17 64040 11922 2 1427.682164 714.849 Heat shock cognate 71 kDa protein OS=Homo sapiens OX=9606 GN=HSPA8 PE=1 SV=1 4.43 2335.1 - 1.14E+07 - - - -0.8545 - 3.543 0.629 - 1236.3 1 2 0 -0.0012 12 0 0 0 1.26E+08 7.60E+08 - - - 7.0148 0.9999 221125_WJC_METTL3_EV_vs_WT_F05.11923.11923.3 1.03E-06 14/40 K.NFYVEHPEVAR[166.11].L "sp|Q92841|DDX17_HUMAN,tr|A0A5H1ZRQ2|A0A5H1ZRQ2_HUMAN,tr|A0A1X7SBZ2|A0A1X7SBZ2_HUMAN" 3 1369.6654 1.21 64041 11923 3 1369.66287 457.5624 Probable ATP-dependent RNA helicase DDX17 OS=Homo sapiens OX=9606 GN=DDX17 PE=1 SV=2 5.4 2335.2 - 772096 - - - -1.861 - 2.426 0.484 - 342.1 1 2 0 -0.0025 11 0 0 0 1.95E+07 1.61E+07 - - - 6.4531 0.9531 221125_WJC_METTL3_EV_vs_WT_F05.11924.11924.3 0.0227 Aug-36 K.ETHADLWPAK.Q "sp|P35606|COPB2_HUMAN,tr|H0Y938|H0Y938_HUMAN,tr|A0A7I2V258|A0A7I2V258_HUMAN,tr|H0YAC7|H0YAC7_HUMAN" 4 1166.572 0.55 64042 11924 3 1166.567079 389.8646 Coatomer subunit beta' OS=Homo sapiens OX=9606 GN=COPB2 PE=1 SV=2 5.32 2335.3 - 687115 - - - -4.2381 - 1.462 0.229 - 78.7 1 2 0 -0.0049 10 0 0 0 1.74E+07 3.16E+07 - - - 2.201 0.9986 221125_WJC_METTL3_EV_vs_WT_F05.11926.11926.3 0.000325 Dec-36 R.NREILDESLR.L sp|Q8WUM4|PDC6I_HUMAN 1 1243.6521 5.54 64044 11926 3 1243.648768 415.558 Programmed cell death 6-interacting protein OS=Homo sapiens OX=9606 GN=PDCD6IP PE=1 SV=1 4.68 2335.6 - 401093 - - - -2.6503 - 2.194 0.387 - 230.9 1 2 1 -0.0033 10 0 0 0 7.80E+07 1.41E+07 - - - 5.1484 0.9918 221125_WJC_METTL3_EV_vs_WT_F05.11930.11930.2 0.00203 14/18 L.ASTLVHSVKK.E "sp|Q9NYF8|BCLF1_HUMAN,tr|E9PKI6|E9PKI6_HUMAN,tr|A0A1W2PQ43|A0A1W2PQ43_HUMAN,tr|E9PK91|E9PK91_HUMAN,tr|E9PJA7|E9PJA7_HUMAN,tr|E9PK09|E9PK09_HUMAN,tr|E9PQN2|E9PQN2_HUMAN" 7 1068.6291 2.25 64046 11930 2 1068.627789 535.3218 Bcl-2-associated transcription factor 1 OS=Homo sapiens OX=9606 GN=BCLAF1 PE=1 SV=2 10 2336.1 - 2.04E+06 - - - -1.268 - 2.539 0.482 - 904.3 1 1 0 -0.0014 10 0 0 0 3.75E+07 1.67E+07 - - - 5.2015 1 221125_WJC_METTL3_EV_vs_WT_F05.11931.11931.3 1.18E-06 Oct-40 R.WGDYDSHDIER[166.11].Y sp|Q6P2Q9|PRP8_HUMAN 1 1401.5825 1.21 64047 11931 3 1401.581829 468.2014 Pre-mRNA-processing-splicing factor 8 OS=Homo sapiens OX=9606 GN=PRPF8 PE=1 SV=2 4.22 2336.2 - 2.18E+06 - - - -0.463 - 2.141 0.598 - 143.7 1 2 0 -0.0006 11 0 0 0 3.36E+07 2.79E+07 - - - 7.3696 0.9999 221125_WJC_METTL3_EV_vs_WT_F05.11932.11932.2 6.56E-07 20-Nov K.GNDPNVNIVPK[136.11].D "sp|Q9Y520|PRC2C_HUMAN,tr|E7EPN9|E7EPN9_HUMAN" 2 1173.6233 1.53 64048 11932 2 1173.623596 587.8189 Protein PRRC2C OS=Homo sapiens OX=9606 GN=PRRC2C PE=1 SV=4 5.84 2336.3 - 1.44E+06 - - - 0.2207 - 2.214 0.54 - 386.7 1 2 0 0.0003 11 0 0 0 4.41E+07 2.88E+07 - - - 5.1795 0.9999 221125_WJC_METTL3_EV_vs_WT_F05.11934.11934.3 1.66E-05 13/48 R.VQIYHNPTANSFR[166.11].V "sp|P50552|VASP_HUMAN,tr|K7ENR7|K7ENR7_HUMAN,tr|K7ENL7|K7ENL7_HUMAN" 3 1555.7771 0.84 64050 11934 3 1555.774832 519.5996 Vasodilator-stimulated phosphoprotein OS=Homo sapiens OX=9606 GN=VASP PE=1 SV=3 8.73 2336.6 - 765479 - - - -1.4546 - 2.408 0.458 - 196.8 1 2 0 -0.0023 13 0 0 0 2.96E+07 3.54E+07 - - - 6.0283 0.9998 221125_WJC_METTL3_EV_vs_WT_F05.11937.11937.2 0.000107 20-Nov K.LFDSTTLEHQK[136.11].T "sp|Q13347|EIF3I_HUMAN,tr|A0A7I2YQT9|A0A7I2YQT9_HUMAN,tr|A0A7I2V613|A0A7I2V613_HUMAN,tr|A0A7I2V3N2|A0A7I2V3N2_HUMAN,tr|A0A7I2YQU2|A0A7I2YQU2_HUMAN,tr|A0A7I2YQI6|A0A7I2YQI6_HUMAN,tr|A0A7I2YQF8|A0A7I2YQF8_HUMAN,tr|Q5TFK1|Q5TFK1_HUMAN,tr|A0A7I2V3U3|A0A7I2V3U3_HUMAN,tr|A0A7I2V607|A0A7I2V607_HUMAN,tr|A0A7I2V640|A0A7I2V640_HUMAN,tr|A0A7P0MRT9|A0A7P0MRT9_HUMAN,tr|A0A7I2V3K6|A0A7I2V3K6_HUMAN,tr|A0A7I2V4S8|A0A7I2V4S8_HUMAN,tr|A0A7I2V5V8|A0A7I2V5V8_HUMAN,tr|A0A7I2V2M3|A0A7I2V2M3_HUMAN,tr|A0A7I2V4C2|A0A7I2V4C2_HUMAN,tr|A0A7I2YQP9|A0A7I2YQP9_HUMAN,tr|A0A7I2YQI2|A0A7I2YQI2_HUMAN,tr|A0A7I2YQC8|A0A7I2YQC8_HUMAN,tr|A0A7I2V685|A0A7I2V685_HUMAN" 21 1325.6707 1.27 64053 11937 2 1325.672301 663.8426 Eukaryotic translation initiation factor 3 subunit I OS=Homo sapiens OX=9606 GN=EIF3I PE=1 SV=1 5.32 2336.9 - 316656 - - - 1.222 - 2.421 0.456 - 395.9 1 2 0 0.0016 11 0 0 0 1.01E+07 7.92E+06 - - - 4.8004 1 221125_WJC_METTL3_EV_vs_WT_F05.11938.11938.2 1.02E-09 13/38 R.VAPAPAAADAEVEQTDAESK.D "sp|O43823|AKAP8_HUMAN,tr|A0A7P0T893|A0A7P0T893_HUMAN" 2 1968.9276 6.49 64054 11938 2 1968.925097 985.4711 A-kinase anchor protein 8 OS=Homo sapiens OX=9606 GN=AKAP8 PE=1 SV=1 3.83 2337.1 - 163157 - - - -1.2865 - 2.981 0.689 - 348.9 1 2 0 -0.0025 20 0 0 0 3.22E+06 4.96E+05 - - - 6.8145 0.9999 221125_WJC_METTL3_EV_vs_WT_F05.11941.11941.2 3.31E-05 17/22 R.RFDDAVVQSDMK.H "sp|P11142|HSP7C_HUMAN,tr|E9PQQ4|E9PQQ4_HUMAN,tr|E9PNE6|E9PNE6_HUMAN,tr|E9PKE3|E9PKE3_HUMAN,tr|E9PN89|E9PN89_HUMAN,tr|E9PLF4|E9PLF4_HUMAN,tr|E9PK54|E9PK54_HUMAN,tr|E9PN25|E9PN25_HUMAN,tr|E9PPY6|E9PPY6_HUMAN,tr|E9PQK7|E9PQK7_HUMAN" 10 1409.6609 0.17 64055 11941 2 1409.658756 705.8377 Heat shock cognate 71 kDa protein OS=Homo sapiens OX=9606 GN=HSPA8 PE=1 SV=1 4.43 2337.5 - 3.38E+06 - - - -1.5309 - 3.186 0.479 - 1153.8 1 2 0 -0.0022 12 0 0 0 1.30E+08 7.61E+08 - - - 5.6271 1 221125_WJC_METTL3_EV_vs_WT_F05.11945.11945.2 6.40E-09 24-Dec F.GDENGTVSLVDTK.S "sp|Q9BQA1|MEP50_HUMAN,tr|H0Y711|H0Y711_HUMAN" 2 1333.6361 4.51 64059 11945 2 1333.633746 667.8253 Methylosome protein 50 OS=Homo sapiens OX=9606 GN=WDR77 PE=1 SV=1 4.03 2337.9 - 561713 - - - -1.7943 - 2.543 0.632 - 679.3 1 1 0 -0.0024 13 0 0 0 1.64E+07 3.64E+06 - - - 6.1037 0.9999 221125_WJC_METTL3_EV_vs_WT_F05.11946.11946.2 2.98E-05 20-Dec K.LFDSTTLEHQK.T "sp|Q13347|EIF3I_HUMAN,tr|A0A7I2YQT9|A0A7I2YQT9_HUMAN,tr|A0A7I2V613|A0A7I2V613_HUMAN,tr|A0A7I2V3N2|A0A7I2V3N2_HUMAN,tr|A0A7I2YQU2|A0A7I2YQU2_HUMAN,tr|A0A7I2YQI6|A0A7I2YQI6_HUMAN,tr|A0A7I2YQF8|A0A7I2YQF8_HUMAN,tr|Q5TFK1|Q5TFK1_HUMAN,tr|A0A7I2V3U3|A0A7I2V3U3_HUMAN,tr|A0A7I2V607|A0A7I2V607_HUMAN,tr|A0A7I2V640|A0A7I2V640_HUMAN,tr|A0A7P0MRT9|A0A7P0MRT9_HUMAN,tr|A0A7I2V3K6|A0A7I2V3K6_HUMAN,tr|A0A7I2V4S8|A0A7I2V4S8_HUMAN,tr|A0A7I2V5V8|A0A7I2V5V8_HUMAN,tr|A0A7I2V2M3|A0A7I2V2M3_HUMAN,tr|A0A7I2V4C2|A0A7I2V4C2_HUMAN,tr|A0A7I2YQP9|A0A7I2YQP9_HUMAN,tr|A0A7I2YQI2|A0A7I2YQI2_HUMAN,tr|A0A7I2YQC8|A0A7I2YQC8_HUMAN,tr|A0A7I2V685|A0A7I2V685_HUMAN" 21 1317.6565 1.27 64060 11946 2 1317.655841 659.8355 Eukaryotic translation initiation factor 3 subunit I OS=Homo sapiens OX=9606 GN=EIF3I PE=1 SV=1 5.32 2338 - 494789 - - - -0.4857 - 2.551 0.419 - 505 1 2 0 -0.0006 11 0 0 0 1.01E+07 7.92E+06 - - - 4.6689 1 221125_WJC_METTL3_EV_vs_WT_F05.11947.11947.2 1.08E-06 14/32 R.VMLGETNPADSKPGTIR.G "sp|O60361|NDK8_HUMAN,sp|P15531|NDKA_HUMAN,sp|P22392|NDKB_HUMAN,tr|Q32Q12|Q32Q12_HUMAN,tr|Q32Q12|Q32Q12_HUMAN,tr|J3KPD9|J3KPD9_HUMAN,tr|E7ERL0|E7ERL0_HUMAN" 7 1784.9091 1.48 64061 11947 2 1784.905769 893.4618 Putative nucleoside diphosphate kinase OS=Homo sapiens OX=9606 GN=NME2P1 PE=5 SV=1 6.04 2338.1 - 423154 - - - -1.8572 - 2.888 0.622 - 490.8 1 2 0 -0.0033 17 0 0 0 2.28E+07 1.54E+07 - - - 6.2415 0.9999 221125_WJC_METTL3_EV_vs_WT_F05.11951.11951.3 0.000118 Oct-36 R.RIEFAEQINK.M sp|Q9H307|PININ_HUMAN 1 1246.667 1.66 64063 11951 3 1246.665187 416.5629 Pinin OS=Homo sapiens OX=9606 GN=PNN PE=1 SV=5 6.14 2338.6 - 916369 - - - -1.443 - 1.894 0.417 - 184.9 1 2 0 -0.0018 10 0 0 0 7.80E+07 4.69E+07 - - - 5.0539 1 221125_WJC_METTL3_EV_vs_WT_F05.11954.11954.2 4.80E-07 16/30 C.GGGGGSFGAGGGFGSR.S sp|P04264|K2C1_HUMAN 1 1283.5643 999 64066 11954 2 1283.563438 642.7894 "Keratin, type II cytoskeletal 1 OS=Homo sapiens OX=9606 GN=KRT1 PE=1 SV=6" 9.75 2338.9 - 594358 - - - -0.6809 - 3.287 0.537 - 669 1 1 0 -0.0009 16 0 0 0 5.92E+07 0.00E+00 - - - 5.9326 1 221125_WJC_METTL3_EV_vs_WT_F05.11959.11959.3 9.08E-08 21/56 R.PLISVYSEKGESSGK.N "sp|P36578|RL4_HUMAN,tr|H3BTP7|H3BTP7_HUMAN,tr|H3BU31|H3BU31_HUMAN" 3 1579.8094 1.57 64069 11959 3 1579.807758 527.6104 60S ribosomal protein L4 OS=Homo sapiens OX=9606 GN=RPL4 PE=1 SV=5 6.56 2339.6 - 906422 - - - -1.0096 - 3.985 0.628 - 541.7 1 1 1 -0.0016 15 0 0 0 3.64E+07 2.32E+07 - - - 9.1487 1 221125_WJC_METTL3_EV_vs_WT_F05.11960.11960.3 4.88E-07 15/48 R.VQIYHNPTANSFR.V "sp|P50552|VASP_HUMAN,tr|K7ENR7|K7ENR7_HUMAN,tr|K7ENL7|K7ENL7_HUMAN" 3 1545.7688 0.91 64070 11960 3 1545.765978 516.2636 Vasodilator-stimulated phosphoprotein OS=Homo sapiens OX=9606 GN=VASP PE=1 SV=3 8.73 2339.7 - 1.77E+06 - - - -1.8418 - 2.742 0.481 - 312.4 1 2 0 -0.0028 13 0 0 0 2.93E+07 3.21E+07 - - - 6.6367 0.9958 221125_WJC_METTL3_EV_vs_WT_F05.11962.11962.2 0.00434 18-Aug R.RIEFAEQINK.M sp|Q9H307|PININ_HUMAN 1 1246.667 1.95 64072 11962 2 1246.661386 624.3408 Pinin OS=Homo sapiens OX=9606 GN=PNN PE=1 SV=5 6.14 2339.9 - 760103 - - - -4.492 - 1.991 0.346 - 260.1 1 2 0 -0.0056 10 0 0 0 4.58E+07 2.35E+07 - - - 3.517 0.9865 221125_WJC_METTL3_EV_vs_WT_F05.11964.11964.3 0.0535 Oct-36 R.FKDLGEENFK.A "sp|P02768|ALBU_HUMAN,tr|A0A087WWT3|A0A087WWT3_HUMAN,tr|B7WNR0|B7WNR0_HUMAN,tr|H7C013|H7C013_HUMAN,tr|A0A0C4DGB6|A0A0C4DGB6_HUMAN,tr|C9JKR2|C9JKR2_HUMAN" 6 1225.5979 13.66 64074 11964 3 1225.595568 409.5399 Albumin OS=Homo sapiens OX=9606 GN=ALB PE=1 SV=2 4.68 2340.2 - 337888 - - - -1.9052 - 1.593 0.271 - 97.3 1 2 1 -0.0023 10 0 0 0 9.59E+07 7.02E+06 - - - 2.9205 1 221125_WJC_METTL3_EV_vs_WT_F05.11966.11966.3 8.50E-06 Dec-40 K.LFDSTTLEHQK[136.11].T "sp|Q13347|EIF3I_HUMAN,tr|A0A7I2YQT9|A0A7I2YQT9_HUMAN,tr|A0A7I2V613|A0A7I2V613_HUMAN,tr|A0A7I2V3N2|A0A7I2V3N2_HUMAN,tr|A0A7I2YQU2|A0A7I2YQU2_HUMAN,tr|A0A7I2YQI6|A0A7I2YQI6_HUMAN,tr|A0A7I2YQF8|A0A7I2YQF8_HUMAN,tr|Q5TFK1|Q5TFK1_HUMAN,tr|A0A7I2V3U3|A0A7I2V3U3_HUMAN,tr|A0A7I2V607|A0A7I2V607_HUMAN,tr|A0A7I2V640|A0A7I2V640_HUMAN,tr|A0A7P0MRT9|A0A7P0MRT9_HUMAN,tr|A0A7I2V3K6|A0A7I2V3K6_HUMAN,tr|A0A7I2V4S8|A0A7I2V4S8_HUMAN,tr|A0A7I2V5V8|A0A7I2V5V8_HUMAN,tr|A0A7I2V2M3|A0A7I2V2M3_HUMAN,tr|A0A7I2V4C2|A0A7I2V4C2_HUMAN,tr|A0A7I2YQP9|A0A7I2YQP9_HUMAN,tr|A0A7I2YQI2|A0A7I2YQI2_HUMAN,tr|A0A7I2YQC8|A0A7I2YQC8_HUMAN,tr|A0A7I2V685|A0A7I2V685_HUMAN" 21 1325.6707 1.2 64075 11966 3 1325.669229 442.8975 Eukaryotic translation initiation factor 3 subunit I OS=Homo sapiens OX=9606 GN=EIF3I PE=1 SV=1 5.32 2340.5 - 4.26E+06 - - - -1.0953 - 2.386 0.521 - 157.9 1 2 0 -0.0015 11 0 0 0 9.98E+07 8.29E+07 - - - 6.8187 0.9958 221125_WJC_METTL3_EV_vs_WT_F05.11968.11968.3 0.00185 Nov-44 R.LYK[136.11]DDQLLDDGK[136.11].T "sp|Q15370|ELOB_HUMAN,tr|B8ZZU8|B8ZZU8_HUMAN" 2 1437.7322 0.6 64076 11968 3 1437.728608 480.2514 Elongin-B OS=Homo sapiens OX=9606 GN=ELOB PE=1 SV=1 4.14 2340.7 - 1.30E+06 - - - -2.5158 - 2.161 0.307 - 156.6 1 2 1 -0.0036 12 0 0 0 4.94E+07 8.20E+07 - - - 4.0977 0.9999 221125_WJC_METTL3_EV_vs_WT_F05.11969.11969.3 0.00256 15/52 R.RGPLAGLGPGSTPR.T sp|Q8WUM0|NU133_HUMAN 1 1334.7419 1.15 64077 11969 3 1334.741804 445.9212 Nuclear pore complex protein Nup133 OS=Homo sapiens OX=9606 GN=NUP133 PE=1 SV=2 12 2340.7 - 926932 - - - -0.0584 - 3.158 0.366 - 357.9 1 2 0 -0.0001 14 0 0 0 2.27E+07 1.97E+07 - - - 5.6765 0.9999 221125_WJC_METTL3_EV_vs_WT_F05.11970.11970.2 0.000951 16/22 K.QIANEIPVSSNR[166.11].R "sp|Q8IZH2|XRN1_HUMAN,tr|H7C5E4|H7C5E4_HUMAN" 2 1336.6974 1.38 64078 11970 2 1336.696716 669.356 5'-3' exoribonuclease 1 OS=Homo sapiens OX=9606 GN=XRN1 PE=1 SV=1 6 2340.9 - 1.12E+06 - - - -0.5476 - 2.51 0.452 - 804.5 1 2 0 -0.0007 12 0 0 0 6.01E+07 4.34E+07 - - - 4.8007 1 221125_WJC_METTL3_EV_vs_WT_F05.11971.11971.2 2.03E-09 13/32 R.VMLGETNPADSK[136.11]PGTIR[166.11].G "sp|O60361|NDK8_HUMAN,sp|P15531|NDKA_HUMAN,sp|P22392|NDKB_HUMAN,tr|Q32Q12|Q32Q12_HUMAN,tr|Q32Q12|Q32Q12_HUMAN,tr|J3KPD9|J3KPD9_HUMAN,tr|E7ERL0|E7ERL0_HUMAN" 7 1802.9316 1.48 64079 11971 2 1802.928867 902.4731 Putative nucleoside diphosphate kinase OS=Homo sapiens OX=9606 GN=NME2P1 PE=5 SV=1 6.04 2341 - 695937 - - - -1.4904 - 2.714 0.665 - 361.5 1 2 0 -0.0027 17 0 0 0 2.28E+07 1.54E+07 - - - 6.4065 0.9994 221125_WJC_METTL3_EV_vs_WT_F05.11973.11973.2 0.00326 16-Sep K.VQFLEQQNK.V sp|P19013|K2C4_HUMAN 1 1132.5877 999 64081 11973 2 1132.585549 567.3011 "Keratin, type II cytoskeletal 4 OS=Homo sapiens OX=9606 GN=KRT4 PE=1 SV=5" 5.97 2341.3 - 260557 - - - -1.8754 - 1.779 0.393 - 377.6 1 2 0 -0.0021 9 0 0 0 1.00E+08 0.00E+00 - - - 3.6096 1 221125_WJC_METTL3_EV_vs_WT_F05.11977.11977.2 6.59E-09 14/28 Q.QAFGNSTGGFDGQAR.Q sp|Q96PK6|RBM14_HUMAN 1 1511.6753 1.79 64083 11977 2 1511.679765 756.8449 RNA-binding protein 14 OS=Homo sapiens OX=9606 GN=RBM14 PE=1 SV=2 5.84 2341.8 - 510438 - - - 2.9411 - 2.845 0.708 - 665.3 1 1 0 0.0044 15 0 0 0 2.42E+07 1.35E+07 - - - 6.8395 1 221125_WJC_METTL3_EV_vs_WT_F05.11983.11983.3 2.82E-05 13/40 K.LFDSTTLEHQK.T "sp|Q13347|EIF3I_HUMAN,tr|A0A7I2YQT9|A0A7I2YQT9_HUMAN,tr|A0A7I2V613|A0A7I2V613_HUMAN,tr|A0A7I2V3N2|A0A7I2V3N2_HUMAN,tr|A0A7I2YQU2|A0A7I2YQU2_HUMAN,tr|A0A7I2YQI6|A0A7I2YQI6_HUMAN,tr|A0A7I2YQF8|A0A7I2YQF8_HUMAN,tr|Q5TFK1|Q5TFK1_HUMAN,tr|A0A7I2V3U3|A0A7I2V3U3_HUMAN,tr|A0A7I2V607|A0A7I2V607_HUMAN,tr|A0A7I2V640|A0A7I2V640_HUMAN,tr|A0A7P0MRT9|A0A7P0MRT9_HUMAN,tr|A0A7I2V3K6|A0A7I2V3K6_HUMAN,tr|A0A7I2V4S8|A0A7I2V4S8_HUMAN,tr|A0A7I2V5V8|A0A7I2V5V8_HUMAN,tr|A0A7I2V2M3|A0A7I2V2M3_HUMAN,tr|A0A7I2V4C2|A0A7I2V4C2_HUMAN,tr|A0A7I2YQP9|A0A7I2YQP9_HUMAN,tr|A0A7I2YQI2|A0A7I2YQI2_HUMAN,tr|A0A7I2YQC8|A0A7I2YQC8_HUMAN,tr|A0A7I2V685|A0A7I2V685_HUMAN" 21 1317.6565 1.21 64087 11983 3 1317.654519 440.2261 Eukaryotic translation initiation factor 3 subunit I OS=Homo sapiens OX=9606 GN=EIF3I PE=1 SV=1 5.32 2342.6 - 2.50E+06 - - - -1.489 - 2.518 0.505 - 183.1 1 2 0 -0.002 11 0 0 0 9.97E+07 8.26E+07 - - - 6.7931 1 221125_WJC_METTL3_EV_vs_WT_F05.11985.11985.3 1.46E-06 Sep-44 R.RFDDAVVQSDMK.H "sp|P11142|HSP7C_HUMAN,tr|E9PQQ4|E9PQQ4_HUMAN,tr|E9PNE6|E9PNE6_HUMAN,tr|E9PKE3|E9PKE3_HUMAN,tr|E9PN89|E9PN89_HUMAN,tr|E9PLF4|E9PLF4_HUMAN,tr|E9PK54|E9PK54_HUMAN,tr|E9PN25|E9PN25_HUMAN,tr|E9PPY6|E9PPY6_HUMAN,tr|E9PQK7|E9PQK7_HUMAN" 10 1409.6609 0.13 64089 11985 3 1409.66015 470.8942 Heat shock cognate 71 kDa protein OS=Homo sapiens OX=9606 GN=HSPA8 PE=1 SV=1 4.43 2342.7 - 1.86E+07 - - - -0.542 - 2.083 0.536 - 168.9 1 2 0 -0.0008 12 0 0 0 3.68E+08 2.81E+09 - - - 6.5497 1 221125_WJC_METTL3_EV_vs_WT_F05.11986.11986.3 6.06E-10 20/56 K.VTATDLDEPDTLHTR.L sp|Q08554|DSC1_HUMAN 1 1682.8111 999 64090 11986 3 1682.811078 561.9443 Desmocollin-1 OS=Homo sapiens OX=9606 GN=DSC1 PE=1 SV=2 4.22 2342.8 - 778861 - - - -0.0392 - 3.342 0.588 - 529.4 1 2 0 -0.0001 15 0 0 0 1.65E+08 0.00E+00 - - - 8.244 0.9918 221125_WJC_METTL3_EV_vs_WT_F05.11987.11987.3 1.23E-05 15/52 A.RGGIGAGLGGGLC[160.03]R.R "sp|Q9NXV2|KCTD5_HUMAN,tr|H3BSS5|H3BSS5_HUMAN" 2 1299.683 1.85 64091 11987 3 1299.680835 434.2349 BTB\POZ domain-containing protein KCTD5 OS=Homo sapiens OX=9606 GN=KCTD5 PE=1 SV=1 10.35 2342.9 - 1.11E+06 - - - -1.6558 - 2.392 0.444 - 305.5 1 1 0 -0.0022 14 0 0 0 3.58E+07 1.94E+07 - - - 5.8073 1 221125_WJC_METTL3_EV_vs_WT_F05.11988.11988.2 4.43E-08 13/28 Q.QAFGNSTGGFDGQAR[166.11].Q sp|Q96PK6|RBM14_HUMAN 1 1521.6836 1.79 64092 11988 2 1521.68747 761.8491 RNA-binding protein 14 OS=Homo sapiens OX=9606 GN=RBM14 PE=1 SV=2 5.84 2343.1 - 551092 - - - 2.5505 - 2.704 0.639 - 494.1 1 1 0 0.0039 15 0 0 0 2.42E+07 1.35E+07 - - - 6.205 0.9969 221125_WJC_METTL3_EV_vs_WT_F05.11989.11989.3 0.0243 Sep-36 K.AKEFTNVYIK.N "sp|Q13310|PABP4_HUMAN,sp|P11940|PABP1_HUMAN,tr|A0A7I2V5W9|A0A7I2V5W9_HUMAN,tr|A0A7I2YQE4|A0A7I2YQE4_HUMAN,tr|A0A7I2V649|A0A7I2V649_HUMAN,tr|B1ANR0|B1ANR0_HUMAN,tr|A0A7I2V4L7|A0A7I2V4L7_HUMAN,tr|H0YCC8|H0YCC8_HUMAN,tr|H0YAR2|H0YAR2_HUMAN,tr|E7ERJ7|E7ERJ7_HUMAN,tr|A0A7I2V598|A0A7I2V598_HUMAN,tr|A0A7I2YQ88|A0A7I2YQ88_HUMAN,tr|H0Y5F5|H0Y5F5_HUMAN,tr|H0YBN4|H0YBN4_HUMAN,tr|A0A087WTT1|A0A087WTT1_HUMAN,tr|A0A7I2YQ90|A0A7I2YQ90_HUMAN,tr|A0A7I2V4N4|A0A7I2V4N4_HUMAN,tr|E7EQV3|E7EQV3_HUMAN" 18 1211.655 1.28 64093 11989 3 1211.654741 404.8923 Polyadenylate-binding protein 4 OS=Homo sapiens OX=9606 GN=PABPC4 PE=1 SV=1 8.54 2343.2 - 389768 - - - -0.2336 - 1.869 0.29 - 106.1 1 2 1 -0.0003 10 0 0 0 1.19E+08 9.30E+07 - - - 3.5996 0.9943 221125_WJC_METTL3_EV_vs_WT_F05.11996.11996.2 1.25E-05 16/28 M.LGETNPADSKPGTIR.G "sp|O60361|NDK8_HUMAN,sp|P15531|NDKA_HUMAN,sp|P22392|NDKB_HUMAN,tr|Q32Q12|Q32Q12_HUMAN,tr|Q32Q12|Q32Q12_HUMAN,tr|J3KPD9|J3KPD9_HUMAN,tr|E7ERL0|E7ERL0_HUMAN" 7 1554.8002 2.41 64098 11996 2 1554.801125 778.4074 Putative nucleoside diphosphate kinase OS=Homo sapiens OX=9606 GN=NME2P1 PE=5 SV=1 6.07 2344.1 - 327098 - - - 0.6046 - 2.901 0.539 - 687.8 1 1 0 0.0009 15 0 0 0 4.06E+06 1.68E+06 - - - 5.6402 0.9937 221125_WJC_METTL3_EV_vs_WT_F05.11999.11999.2 0.104 22-Jul R.ETAEADVASLNR.R "tr|F5H7S3|F5H7S3_HUMAN,tr|H0YKJ4|H0YKJ4_HUMAN,tr|H0YK48|H0YK48_HUMAN,tr|B7Z596|B7Z596_HUMAN,tr|A0A494BZZ2|A0A494BZZ2_HUMAN,tr|H7BYY1|H7BYY1_HUMAN" 6 1274.6103 1.14 64101 11999 2 1274.614212 638.3124 Tropomyosin alpha-1 chain OS=Homo sapiens OX=9606 GN=TPM1 PE=1 SV=2 4.14 2344.5 - 150707 - - - 3.1013 - 1.311 0.325 - 129.6 1 2 0 0.004 12 0 0 0 2.36E+06 2.07E+06 - - - 2.1527 0.9998 221125_WJC_METTL3_EV_vs_WT_F05.12002.12002.3 1.65E-06 Dec-40 K.AEDK[136.11]EWMPVTK[136.11].L "sp|P15880|RS2_HUMAN,tr|E9PQD7|E9PQD7_HUMAN,tr|E9PPT0|E9PPT0_HUMAN,tr|E9PMM9|E9PMM9_HUMAN" 4 1348.6668 0.91 64102 12002 3 1348.666205 450.5629 40S ribosomal protein S2 OS=Homo sapiens OX=9606 GN=RPS2 PE=1 SV=2 4.68 2344.9 - 6.65E+06 - - - -0.4323 - 2.243 0.486 - 289.8 1 2 1 -0.0006 11 0 0 0 1.05E+08 1.16E+08 - - - 6.2531 0.9997 221125_WJC_METTL3_EV_vs_WT_F05.12003.12003.3 0.00663 Oct-44 K.VMSQEIQEQLHK.Q "sp|Q14204|DYHC1_HUMAN,tr|A0A7P0T8N2|A0A7P0T8N2_HUMAN,tr|A0A7P0T9C4|A0A7P0T9C4_HUMAN,tr|A0A7P0TBJ7|A0A7P0TBJ7_HUMAN,tr|A0A7P0T9K2|A0A7P0T9K2_HUMAN,tr|A0A2R8Y706|A0A2R8Y706_HUMAN,tr|A0A7P0T916|A0A7P0T916_HUMAN,tr|A0A7P0TB75|A0A7P0TB75_HUMAN,tr|A0A7P0T8W5|A0A7P0T8W5_HUMAN,tr|A0A7P0TAF3|A0A7P0TAF3_HUMAN,tr|A0A7P0T9F1|A0A7P0T9F1_HUMAN,tr|A0A7P0TAW9|A0A7P0TAW9_HUMAN,tr|A0A7P0TA13|A0A7P0TA13_HUMAN,tr|A0A7P0T7V5|A0A7P0T7V5_HUMAN,tr|A0A7P0T9R4|A0A7P0T9R4_HUMAN,tr|A0A2R8Y5T0|A0A2R8Y5T0_HUMAN,tr|A0A2R8YFZ7|A0A2R8YFZ7_HUMAN,tr|A0A7P0T825|A0A7P0T825_HUMAN,tr|A0A2R8Y6H2|A0A2R8Y6H2_HUMAN,tr|A0A7P0TAM4|A0A7P0TAM4_HUMAN" 20 1468.7344 0.7 64103 12003 3 1468.733114 490.5854 Cytoplasmic dynein 1 heavy chain 1 OS=Homo sapiens OX=9606 GN=DYNC1H1 PE=1 SV=5 5.4 2345 - 1.00E+06 - - - -0.8851 - 1.924 0.337 - 135.2 1 2 0 -0.0013 12 0 0 0 1.10E+07 1.58E+07 - - - 4.1108 0.9999 221125_WJC_METTL3_EV_vs_WT_F05.12004.12004.3 6.01E-05 Oct-44 K.VMSQEIQEQLHK[136.11].Q "sp|Q14204|DYHC1_HUMAN,tr|A0A7P0T8N2|A0A7P0T8N2_HUMAN,tr|A0A7P0T9C4|A0A7P0T9C4_HUMAN,tr|A0A7P0TBJ7|A0A7P0TBJ7_HUMAN,tr|A0A7P0T9K2|A0A7P0T9K2_HUMAN,tr|A0A2R8Y706|A0A2R8Y706_HUMAN,tr|A0A7P0T916|A0A7P0T916_HUMAN,tr|A0A7P0TB75|A0A7P0TB75_HUMAN,tr|A0A7P0T8W5|A0A7P0T8W5_HUMAN,tr|A0A7P0TAF3|A0A7P0TAF3_HUMAN,tr|A0A7P0T9F1|A0A7P0T9F1_HUMAN,tr|A0A7P0TAW9|A0A7P0TAW9_HUMAN,tr|A0A7P0TA13|A0A7P0TA13_HUMAN,tr|A0A7P0T7V5|A0A7P0T7V5_HUMAN,tr|A0A7P0T9R4|A0A7P0T9R4_HUMAN,tr|A0A2R8Y5T0|A0A2R8Y5T0_HUMAN,tr|A0A2R8YFZ7|A0A2R8YFZ7_HUMAN,tr|A0A7P0T825|A0A7P0T825_HUMAN,tr|A0A2R8Y6H2|A0A2R8Y6H2_HUMAN,tr|A0A7P0TAM4|A0A7P0TAM4_HUMAN" 20 1476.7486 0.71 64104 12004 3 1476.747754 493.2568 Cytoplasmic dynein 1 heavy chain 1 OS=Homo sapiens OX=9606 GN=DYNC1H1 PE=1 SV=5 5.4 2345 - 1.28E+06 - - - -0.5824 - 2.211 0.395 - 139.7 1 2 0 -0.0009 12 0 0 0 1.14E+07 1.60E+07 - - - 5.1429 0.9947 221125_WJC_METTL3_EV_vs_WT_F05.12005.12005.3 0.0142 Dec-48 K.LISQIQPEVDR[166.11]ER[166.11].A "sp|Q9NRZ9|HELLS_HUMAN,tr|A0A087WSW7|A0A087WSW7_HUMAN,tr|A0A0B4J1V9|A0A0B4J1V9_HUMAN,tr|F6XU50|F6XU50_HUMAN" 4 1601.864 0.22 64105 12005 3 1601.862265 534.9619 Lymphoid-specific helicase OS=Homo sapiens OX=9606 GN=HELLS PE=1 SV=1 4.68 2345.2 - 809325 - - - -1.0894 - 1.649 0.299 - 165.3 1 2 1 -0.0017 13 0 0 0 2.30E+06 1.05E+07 - - - 3.2292 0.9983 221125_WJC_METTL3_EV_vs_WT_F05.12009.12009.2 2.49E-07 20-Dec K.AEDK[136.11]EWMPVTK[136.11].L "sp|P15880|RS2_HUMAN,tr|E9PQD7|E9PQD7_HUMAN,tr|E9PPT0|E9PPT0_HUMAN,tr|E9PMM9|E9PMM9_HUMAN" 4 1348.6668 0.9 64109 12009 2 1348.664812 675.3407 40S ribosomal protein S2 OS=Homo sapiens OX=9606 GN=RPS2 PE=1 SV=2 4.68 2345.7 - 449403 - - - -1.4652 - 2.407 0.509 - 553.4 1 2 1 -0.002 11 0 0 0 9.12E+06 1.01E+07 - - - 5.1761 0.9928 221125_WJC_METTL3_EV_vs_WT_F05.12010.12010.3 0.0171 Oct-32 R.K[136.11]NYNWAITR[166.11].E sp|Q9BYN8|RT26_HUMAN 1 1182.6265 1.1 64110 12010 3 1182.624429 395.2161 "28S ribosomal protein S26, mitochondrial OS=Homo sapiens OX=9606 GN=MRPS26 PE=1 SV=1" 9.99 2345.8 - 425198 - - - -1.7191 - 1.73 0.185 - 193.3 1 2 0 -0.002 9 0 0 0 1.08E+07 9.83E+06 - - - 2.2539 0.9997 221125_WJC_METTL3_EV_vs_WT_F05.12011.12011.3 0.00801 Nov-32 R.KNYNWAITR.E sp|Q9BYN8|RT26_HUMAN 1 1164.604 1.08 64111 12011 3 1164.603972 389.2086 "28S ribosomal protein S26, mitochondrial OS=Homo sapiens OX=9606 GN=MRPS26 PE=1 SV=1" 9.99 2345.9 - 385321 - - - -0.0172 - 1.668 0.362 - 234.3 1 2 0 0 9 0 0 0 1.08E+07 1.00E+07 - - - 4.1179 0.973 221125_WJC_METTL3_EV_vs_WT_F05.12014.12014.3 0.015 Jul-40 K.HLTDPSYGIPR.E "sp|Q9H9Y6|RPA2_HUMAN,tr|F8WDS4|F8WDS4_HUMAN,tr|C9JS83|C9JS83_HUMAN,tr|F8WCS3|F8WCS3_HUMAN,tr|F8WBB9|F8WBB9_HUMAN,tr|C9JJG2|C9JJG2_HUMAN,tr|F8WAK7|F8WAK7_HUMAN" 7 1254.6357 1.01 64114 12014 3 1254.63605 419.2192 DNA-directed RNA polymerase I subunit RPA2 OS=Homo sapiens OX=9606 GN=POLR1B PE=1 SV=2 6.74 2346.3 - 243396 - - - 0.2901 - 1.692 0.131 - 57.5 4 2 0 0.0004 11 0 0 0 3.66E+06 3.63E+06 - - - 1.2158 0.9998 221125_WJC_METTL3_EV_vs_WT_F05.12015.12015.2 1.61E-07 24-Sep R.LQSQLQENEEFQK.S "sp|Q9UPN3|MACF1_HUMAN,tr|H3BQK9|H3BQK9_HUMAN,tr|A0A7P0MQR8|A0A7P0MQR8_HUMAN,tr|H0Y390|H0Y390_HUMAN,tr|H3BPE1|H3BPE1_HUMAN,tr|A0A669KB06|A0A669KB06_HUMAN,tr|A0A590UJG2|A0A590UJG2_HUMAN" 7 1619.7791 3.46 64115 12015 2 1619.775763 810.8968 "Microtubule-actin cross-linking factor 1, isoforms 1\2\3\5 OS=Homo sapiens OX=9606 GN=MACF1 PE=1 SV=4" 4.25 2346.5 - 238452 - - - -2.0694 - 2.408 0.587 - 272.9 1 2 0 -0.0034 13 0 0 0 3.65E+06 1.06E+06 - - - 5.631 0.9994 221125_WJC_METTL3_EV_vs_WT_F05.12018.12018.3 0.00542 Sep-36 R.NNRYPNLQLR.E "sp|Q14671|PUM1_HUMAN,tr|Q5T1Z8|Q5T1Z8_HUMAN,tr|H0YDK8|H0YDK8_HUMAN,tr|H0YEH2|H0YEH2_HUMAN,tr|Q5T1Z4|Q5T1Z4_HUMAN,tr|E9PR38|E9PR38_HUMAN" 6 1286.6844 1.6 64117 12018 3 1286.683932 429.9021 Pumilio homolog 1 OS=Homo sapiens OX=9606 GN=PUM1 PE=1 SV=3 10.84 2346.9 - 453789 - - - -0.3381 - 2.069 0.385 - 144.1 1 2 1 -0.0004 10 0 0 0 6.07E+06 3.81E+06 - - - 4.9556 0.997 221125_WJC_METTL3_EV_vs_WT_F05.12020.12020.2 0.00433 18-Oct R.FKDLGEENFK.A "sp|P02768|ALBU_HUMAN,tr|A0A087WWT3|A0A087WWT3_HUMAN,tr|B7WNR0|B7WNR0_HUMAN,tr|H7C013|H7C013_HUMAN,tr|A0A0C4DGB6|A0A0C4DGB6_HUMAN,tr|C9JKR2|C9JKR2_HUMAN" 6 1225.5979 999 64118 12020 2 1225.597544 613.8062 Albumin OS=Homo sapiens OX=9606 GN=ALB PE=1 SV=2 4.68 2347.2 - 1.12E+06 - - - -0.2929 - 2.044 0.363 - 205.8 1 2 1 -0.0004 10 0 0 0 1.32E+07 0.00E+00 - - - 3.7175 0.9998 221125_WJC_METTL3_EV_vs_WT_F05.12022.12022.3 0.000471 Nov-48 K.LGDLKEEGDVMDK.T "sp|Q14671|PUM1_HUMAN,tr|Q5T1Z8|Q5T1Z8_HUMAN,tr|H0YEH2|H0YEH2_HUMAN,tr|Q5T1Z4|Q5T1Z4_HUMAN" 4 1447.6865 3.9 64120 12022 3 1447.685262 483.5694 Pumilio homolog 1 OS=Homo sapiens OX=9606 GN=PUM1 PE=1 SV=3 4.11 2347.3 - 1.42E+06 - - - -0.8275 - 2.64 0.465 - 132.2 1 2 1 -0.0012 13 0 0 0 2.19E+07 5.61E+06 - - - 6.356 0.9938 221125_WJC_METTL3_EV_vs_WT_F05.12023.12023.2 0.005 18-Nov K.AKEFTNVYIK.N "sp|Q13310|PABP4_HUMAN,sp|P11940|PABP1_HUMAN,tr|A0A7I2V5W9|A0A7I2V5W9_HUMAN,tr|A0A7I2YQE4|A0A7I2YQE4_HUMAN,tr|A0A7I2V649|A0A7I2V649_HUMAN,tr|B1ANR0|B1ANR0_HUMAN,tr|A0A7I2V4L7|A0A7I2V4L7_HUMAN,tr|H0YCC8|H0YCC8_HUMAN,tr|H0YAR2|H0YAR2_HUMAN,tr|E7ERJ7|E7ERJ7_HUMAN,tr|A0A7I2V598|A0A7I2V598_HUMAN,tr|A0A7I2YQ88|A0A7I2YQ88_HUMAN,tr|H0Y5F5|H0Y5F5_HUMAN,tr|H0YBN4|H0YBN4_HUMAN,tr|A0A087WTT1|A0A087WTT1_HUMAN,tr|A0A7I2YQ90|A0A7I2YQ90_HUMAN,tr|A0A7I2V4N4|A0A7I2V4N4_HUMAN,tr|E7EQV3|E7EQV3_HUMAN" 18 1211.655 1.36 64121 12023 2 1211.657618 606.8348 Polyadenylate-binding protein 4 OS=Homo sapiens OX=9606 GN=PABPC4 PE=1 SV=1 8.54 2347.4 - 895753 - - - 2.1409 - 2.099 0.385 - 226.6 1 2 1 0.0026 10 0 0 0 1.68E+07 1.24E+07 - - - 3.9534 0.9892 221125_WJC_METTL3_EV_vs_WT_F05.12025.12025.3 5.82E-05 Oct-52 A.R[166.11]GGIGAGLGGGLC[160.03]R[166.11].R "sp|Q9NXV2|KCTD5_HUMAN,tr|H3BSS5|H3BSS5_HUMAN" 2 1319.6995 1.77 64123 12025 3 1319.699605 440.9071 BTB\POZ domain-containing protein KCTD5 OS=Homo sapiens OX=9606 GN=KCTD5 PE=1 SV=1 10.35 2347.6 - 837777 - - - 0.0591 - 2.269 0.398 - 129.7 1 1 0 0.0001 14 0 0 0 3.59E+07 2.03E+07 - - - 5.1547 0.998 221125_WJC_METTL3_EV_vs_WT_F05.12026.12026.3 0.0166 Nov-44 R.STVLGLPQHVQK.E sp|Q9P206|K1522_HUMAN 1 1305.7405 1.36 64124 12026 3 1305.741881 436.2541 Uncharacterized protein KIAA1522 OS=Homo sapiens OX=9606 GN=KIAA1522 PE=1 SV=2 8.49 2347.8 - 577050 - - - 1.0691 - 2.108 0.208 - 198 1 2 0 0.0014 12 0 0 0 6.44E+06 4.73E+06 - - - 2.9257 0.9985 221125_WJC_METTL3_EV_vs_WT_F05.12028.12028.2 1.21E-05 22-Oct R.LYKDDQLLDDGK.T "sp|Q15370|ELOB_HUMAN,tr|B8ZZU8|B8ZZU8_HUMAN" 2 1421.7038 0.68 64126 12028 2 1421.70465 711.8592 Elongin-B OS=Homo sapiens OX=9606 GN=ELOB PE=1 SV=1 4.14 2348 - 482227 - - - 0.5803 - 2.016 0.545 - 258.9 1 2 1 0.0008 12 0 0 0 3.50E+06 5.14E+06 - - - 4.9109 0.9999 221125_WJC_METTL3_EV_vs_WT_F05.12029.12029.3 8.10E-05 Nov-32 K.SYSFDEIRK.N "sp|P43490|NAMPT_HUMAN,tr|A0A7P0T862|A0A7P0T862_HUMAN,tr|A0A7P0T931|A0A7P0T931_HUMAN,tr|A0A7P0T973|A0A7P0T973_HUMAN,tr|A0A7P0T895|A0A7P0T895_HUMAN,tr|A0A7P0Z437|A0A7P0Z437_HUMAN,tr|A0A7P0T9I9|A0A7P0T9I9_HUMAN" 7 1143.556 0.78 64127 12029 3 1143.557721 382.1926 Nicotinamide phosphoribosyltransferase OS=Homo sapiens OX=9606 GN=NAMPT PE=1 SV=1 5.79 2348.1 - 468702 - - - 1.4717 - 1.928 0.497 - 188.6 1 2 0 0.0017 9 0 0 0 5.08E+06 6.48E+06 - - - 6.0591 1 221125_WJC_METTL3_EV_vs_WT_F05.12030.12030.2 1.62E-08 16/28 K.VTATDLDEPDTLHTR.L sp|Q08554|DSC1_HUMAN 1 1682.8111 999 64128 12030 2 1682.810526 842.4128 Desmocollin-1 OS=Homo sapiens OX=9606 GN=DSC1 PE=1 SV=2 4.22 2348.3 - 450763 - - - -0.3672 - 3.334 0.664 - 861.5 1 2 0 -0.0006 15 0 0 0 5.86E+06 0.00E+00 - - - 6.9056 0.9996 221125_WJC_METTL3_EV_vs_WT_F05.12033.12033.2 5.65E-06 14/26 K.AQVARPGGDTIFGK.L "sp|P49773|HINT1_HUMAN,tr|H0YC49|H0YC49_HUMAN,tr|A0A6Q8PGQ8|A0A6Q8PGQ8_HUMAN,tr|D6RE99|D6RE99_HUMAN,tr|D6REP8|D6REP8_HUMAN,tr|D6RC06|D6RC06_HUMAN,tr|D6RD60|D6RD60_HUMAN" 7 1415.7521 1.98 64131 12033 2 1415.750534 708.8833 Adenosine 5'-monophosphoramidase HINT1 OS=Homo sapiens OX=9606 GN=HINT1 PE=1 SV=2 8.79 2348.7 - 286451 - - - -1.1153 - 2.666 0.282 - 525.8 1 2 0 -0.0016 14 0 0 0 9.28E+06 4.69E+06 - - - 3.5841 0.9977 221125_WJC_METTL3_EV_vs_WT_F05.12038.12038.3 0.0756 Jul-52 K.AQVARPGGDTIFGK.L "sp|P49773|HINT1_HUMAN,tr|H0YC49|H0YC49_HUMAN,tr|A0A6Q8PGQ8|A0A6Q8PGQ8_HUMAN,tr|D6RE99|D6RE99_HUMAN,tr|D6REP8|D6REP8_HUMAN,tr|D6RC06|D6RC06_HUMAN,tr|D6RD60|D6RD60_HUMAN" 7 1415.7521 1.93 64134 12038 3 1415.753322 472.9246 Adenosine 5'-monophosphoramidase HINT1 OS=Homo sapiens OX=9606 GN=HINT1 PE=1 SV=2 8.79 2349.2 - 1.09E+07 - - - 0.854 - 1.649 0.259 - 74.9 1 2 0 0.0012 14 0 0 0 1.69E+08 8.77E+07 - - - 2.7565 0.9727 221125_WJC_METTL3_EV_vs_WT_F05.12039.12039.3 0.0404 Aug-36 K.AK[136.11]EFTNVYIK[136.11].N "sp|Q13310|PABP4_HUMAN,sp|P11940|PABP1_HUMAN,tr|A0A7I2V5W9|A0A7I2V5W9_HUMAN,tr|A0A7I2YQE4|A0A7I2YQE4_HUMAN,tr|A0A7I2V649|A0A7I2V649_HUMAN,tr|B1ANR0|B1ANR0_HUMAN,tr|A0A7I2V4L7|A0A7I2V4L7_HUMAN,tr|H0YCC8|H0YCC8_HUMAN,tr|H0YAR2|H0YAR2_HUMAN,tr|E7ERJ7|E7ERJ7_HUMAN,tr|A0A7I2V598|A0A7I2V598_HUMAN,tr|A0A7I2YQ88|A0A7I2YQ88_HUMAN,tr|H0Y5F5|H0Y5F5_HUMAN,tr|H0YBN4|H0YBN4_HUMAN,tr|A0A087WTT1|A0A087WTT1_HUMAN,tr|A0A7I2YQ90|A0A7I2YQ90_HUMAN,tr|A0A7I2V4N4|A0A7I2V4N4_HUMAN,tr|E7EQV3|E7EQV3_HUMAN" 18 1227.6834 1.28 64135 12039 3 1227.68319 410.2351 Polyadenylate-binding protein 4 OS=Homo sapiens OX=9606 GN=PABPC4 PE=1 SV=1 8.54 2349.3 - 9.09E+06 - - - -0.1906 - 1.502 0.214 - 74.6 1 2 1 -0.0002 10 0 0 0 1.19E+08 9.30E+07 - - - 2.1138 0.9997 221125_WJC_METTL3_EV_vs_WT_F05.12040.12040.3 0.00234 Sep-52 K.AQVAR[166.11]PGGDTIFGK[136.11].L "sp|P49773|HINT1_HUMAN,tr|H0YC49|H0YC49_HUMAN,tr|A0A6Q8PGQ8|A0A6Q8PGQ8_HUMAN,tr|D6RE99|D6RE99_HUMAN,tr|D6REP8|D6REP8_HUMAN,tr|D6RC06|D6RC06_HUMAN,tr|D6RD60|D6RD60_HUMAN" 7 1433.7746 1.92 64136 12040 3 1433.774768 478.9321 Adenosine 5'-monophosphoramidase HINT1 OS=Homo sapiens OX=9606 GN=HINT1 PE=1 SV=2 8.79 2349.3 - 7.44E+06 - - - 0.129 - 1.773 0.378 - 119.2 1 2 0 0.0002 14 0 0 0 1.68E+08 8.72E+07 - - - 4.2762 0.9999 221125_WJC_METTL3_EV_vs_WT_F05.12041.12041.2 2.69E-05 13/26 K.NTGVILANDANAER.L sp|P46087|NOP2_HUMAN 1 1456.727 0.75 64137 12041 2 1456.726771 729.3708 Probable 28S rRNA (cytosine(4447)-C(5))-methyltransferase OS=Homo sapiens OX=9606 GN=NOP2 PE=1 SV=2 4.37 2349.4 - 611334 - - - -0.1709 - 2.828 0.463 - 657.2 1 2 0 -0.0002 14 0 0 0 7.44E+06 9.91E+06 - - - 5.0694 0.9987 221125_WJC_METTL3_EV_vs_WT_F05.12042.12042.2 0.000141 20-Dec R.EK[136.11]LEMEMEAAR[166.11].H "sp|Q15233|NONO_HUMAN,tr|A0A7I2V535|A0A7I2V535_HUMAN,tr|A0A7I2V4N2|A0A7I2V4N2_HUMAN,tr|A0A7I2V4K9|A0A7I2V4K9_HUMAN,tr|A0A7I2V464|A0A7I2V464_HUMAN,tr|A0A7P0MRW0|A0A7P0MRW0_HUMAN,tr|H7C367|H7C367_HUMAN,tr|A0A7I2V4J2|A0A7I2V4J2_HUMAN,tr|A0A7I2V5Y7|A0A7I2V5Y7_HUMAN,tr|C9JYS8|C9JYS8_HUMAN" 10 1353.6387 0.67 64138 12042 2 1353.637767 677.8266 Non-POU domain-containing octamer-binding protein OS=Homo sapiens OX=9606 GN=NONO PE=1 SV=4 4.49 2349.6 - 595962 - - - -0.7203 - 2.174 0.535 - 497.2 1 2 1 -0.001 11 0 0 0 5.69E+06 8.55E+06 - - - 5.093 1 221125_WJC_METTL3_EV_vs_WT_F05.12043.12043.2 4.32E-07 17/22 R.DYQDNK[136.11]ADVILK[136.11].Y "sp|O14602|IF1AY_HUMAN,sp|P47813|IF1AX_HUMAN,tr|X6RAC9|X6RAC9_HUMAN" 3 1436.7482 0.69 64139 12043 2 1436.747184 719.3814 "Eukaryotic translation initiation factor 1A, Y-chromosomal OS=Homo sapiens OX=9606 GN=EIF1AY PE=1 SV=4" 4.43 2349.7 - 484758 - - - -0.7134 - 3.309 0.566 - 1029.7 1 2 1 -0.001 12 0 0 0 1.04E+07 1.50E+07 - - - 6.3697 0.999 221125_WJC_METTL3_EV_vs_WT_F05.12044.12044.2 0.072 16-Sep R.K[136.11]NYNWAITR[166.11].E sp|Q9BYN8|RT26_HUMAN 1 1182.6265 3.99 64140 12044 2 1182.629926 592.3205 "28S ribosomal protein S26, mitochondrial OS=Homo sapiens OX=9606 GN=MRPS26 PE=1 SV=1" 9.99 2349.8 - 406587 - - - 2.9291 - 2.059 0.382 - 288.2 1 2 0 0.0035 9 0 0 0 2.13E+07 5.33E+06 - - - 3.9508 0.9999 221125_WJC_METTL3_EV_vs_WT_F05.12046.12046.3 0.00198 Nov-52 M.VFFTC[160.03]NAC[160.03]GESVK[136.11]K[136.11].L "sp|Q9NX58|LYAR_HUMAN,tr|D6RDJ1|D6RDJ1_HUMAN" 2 1661.7876 0.53 64142 12046 3 1661.786879 554.9365 Cell growth-regulating nucleolar protein OS=Homo sapiens OX=9606 GN=LYAR PE=1 SV=2 8.02 2350 - 294770 - - - -0.4634 - 1.979 0.41 - 90.3 1 2 0 -0.0008 14 0 0 0 1.58E+06 2.97E+06 - - - 4.9249 0.9901 221125_WJC_METTL3_EV_vs_WT_F05.12049.12049.3 0.146 Aug-40 K.AGVSVK[136.11]PFQVK[136.11].N "sp|Q02880|TOP2B_HUMAN,tr|E9PCY5|E9PCY5_HUMAN" 2 1174.7045 1.21 64145 12049 3 1174.704228 392.5754 DNA topoisomerase 2-beta OS=Homo sapiens OX=9606 GN=TOP2B PE=1 SV=3 10 2350.4 - 163422 - - - -0.2264 - 1.5 0.19 - 51.9 1 2 0 -0.0003 11 0 0 0 2.69E+06 2.23E+06 - - - 1.8101 0.9999 221125_WJC_METTL3_EV_vs_WT_F05.12052.12052.3 1.29E-05 Dec-40 K.AEDKEWMPVTK.L "sp|P15880|RS2_HUMAN,tr|E9PQD7|E9PQD7_HUMAN,tr|E9PPT0|E9PPT0_HUMAN,tr|E9PMM9|E9PMM9_HUMAN" 4 1332.6384 0.91 64147 12052 3 1332.6394 445.2201 40S ribosomal protein S2 OS=Homo sapiens OX=9606 GN=RPS2 PE=1 SV=2 4.68 2350.8 - 1.14E+07 - - - 0.7594 - 2.263 0.53 - 292.1 1 2 1 0.001 11 0 0 0 1.05E+08 1.16E+08 - - - 6.7688 0.9997 221125_WJC_METTL3_EV_vs_WT_F05.12054.12054.3 0.00103 Nov-52 K.FLETESHPSIPPPK.L "sp|Q15643|TRIPB_HUMAN,tr|H0YJ97|H0YJ97_HUMAN" 2 1577.809 1.41 64148 12054 3 1577.807647 526.9436 Thyroid receptor-interacting protein 11 OS=Homo sapiens OX=9606 GN=TRIP11 PE=1 SV=3 5.4 2351 - 1.58E+06 - - - -0.8315 - 1.495 0.403 - 92.8 1 2 0 -0.0013 14 0 0 0 2.42E+07 1.72E+07 - - - 4.1013 0.9974 221125_WJC_METTL3_EV_vs_WT_F05.12055.12055.2 0.0231 18-Oct K.AK[136.11]EFTNVYIK[136.11].N "sp|Q13310|PABP4_HUMAN,sp|P11940|PABP1_HUMAN,tr|A0A7I2V5W9|A0A7I2V5W9_HUMAN,tr|A0A7I2YQE4|A0A7I2YQE4_HUMAN,tr|A0A7I2V649|A0A7I2V649_HUMAN,tr|B1ANR0|B1ANR0_HUMAN,tr|A0A7I2V4L7|A0A7I2V4L7_HUMAN,tr|H0YCC8|H0YCC8_HUMAN,tr|H0YAR2|H0YAR2_HUMAN,tr|E7ERJ7|E7ERJ7_HUMAN,tr|A0A7I2V598|A0A7I2V598_HUMAN,tr|A0A7I2YQ88|A0A7I2YQ88_HUMAN,tr|H0Y5F5|H0Y5F5_HUMAN,tr|H0YBN4|H0YBN4_HUMAN,tr|A0A087WTT1|A0A087WTT1_HUMAN,tr|A0A7I2YQ90|A0A7I2YQ90_HUMAN,tr|A0A7I2V4N4|A0A7I2V4N4_HUMAN,tr|E7EQV3|E7EQV3_HUMAN" 18 1227.6834 1.39 64149 12055 2 1227.683632 614.849 Polyadenylate-binding protein 4 OS=Homo sapiens OX=9606 GN=PABPC4 PE=1 SV=1 8.54 2351.1 - 1.56E+06 - - - 0.1694 - 2.174 0.364 - 209.6 1 2 1 0.0002 10 0 0 0 1.72E+07 1.24E+07 - - - 3.8971 1 221125_WJC_METTL3_EV_vs_WT_F05.12056.12056.2 2.34E-10 18/28 R.HGGGGGGFGGGGFGS.R sp|P35908|K22E_HUMAN 1 1163.4744 - 64150 12056 2 1163.474679 582.7445 "Keratin, type II cytoskeletal 2 epidermal OS=Homo sapiens OX=9606 GN=KRT2 PE=1 SV=2" 6.74 2351.3 - 1.34E+06 - - - 0.2106 - 2.832 0.718 - 508 1 1 0 0.0002 15 0 0 0 - - - - - 6.9034 0.9999 221125_WJC_METTL3_EV_vs_WT_F05.12057.12057.2 0.000155 26-Nov K.NTGVILANDANAER[166.11].L sp|P46087|NOP2_HUMAN 1 1466.7353 0.75 64151 12057 2 1466.735945 734.3749 Probable 28S rRNA (cytosine(4447)-C(5))-methyltransferase OS=Homo sapiens OX=9606 GN=NOP2 PE=1 SV=2 4.37 2351.3 - 808825 - - - 0.4466 - 2.426 0.491 - 451.1 1 2 0 0.0007 14 0 0 0 7.44E+06 9.91E+06 - - - 4.8913 0.9997 221125_WJC_METTL3_EV_vs_WT_F05.12060.12060.2 0.00109 14-Sep K.AWEDYYKK.Q sp|Q96I24|FUBP3_HUMAN 1 1101.5131 1.25 64154 12060 2 1101.51458 551.7638 Far upstream element-binding protein 3 OS=Homo sapiens OX=9606 GN=FUBP3 PE=1 SV=2 6.11 2351.7 - 625981 - - - 1.3336 - 1.792 0.487 - 407.2 1 2 0 0.0015 8 0 0 0 1.46E+07 1.17E+07 - - - 4.3968 0.9984 221125_WJC_METTL3_EV_vs_WT_F05.12061.12061.2 0.0297 15/22 R.DYQDNKADVILK.Y "sp|O14602|IF1AY_HUMAN,sp|P47813|IF1AX_HUMAN,tr|X6RAC9|X6RAC9_HUMAN" 3 1420.7198 0.69 64155 12061 2 1420.720706 711.3672 "Eukaryotic translation initiation factor 1A, Y-chromosomal OS=Homo sapiens OX=9606 GN=EIF1AY PE=1 SV=4" 4.43 2351.8 - 612864 - - - 0.6314 - 2.571 0.44 - 717.4 1 2 1 0.0009 12 0 0 0 1.04E+07 1.50E+07 - - - 4.7752 0.8104 221125_WJC_METTL3_EV_vs_WT_F05.12062.12062.2 0.125 20-May K.K[136.11]NGSDC[160.03]GSLGK[136.11].K sp|Q9Y6Q3|ZFP37_HUMAN 1 1137.5419 0.06 64156 12062 2 1137.536146 569.7782 Zinc finger protein 37 homolog OS=Homo sapiens OX=9606 GN=ZFP37 PE=2 SV=3 8.2 2351.9 - 606073 - - - -5.0776 - 1.122 0.223 - 33.8 11 2 0 -0.0058 11 0 0 0 3.86E+05 6.50E+06 - - - 0.5325 1 221125_WJC_METTL3_EV_vs_WT_F05.12065.12065.2 3.14E-07 13/24 R.NVETNQC[160.03]LDNMAR.K sp|Q10472|GALT1_HUMAN 1 1563.677 1.62 64159 12065 2 1563.676647 782.8458 Polypeptide N-acetylgalactosaminyltransferase 1 OS=Homo sapiens OX=9606 GN=GALNT1 PE=1 SV=1 4.37 2352.3 - 275205 - - - -0.2098 - 2.615 0.647 - 539.5 1 2 0 -0.0003 13 0 0 0 9.15E+06 5.66E+06 - - - 6.2868 0.9977 221125_WJC_METTL3_EV_vs_WT_F05.12066.12066.3 0.0492 Nov-56 K.EVVK[136.11]PVPITSPAVSK[136.11].V "sp|Q96HC4|PDLI5_HUMAN,tr|A0A0D9SFR4|A0A0D9SFR4_HUMAN" 2 1565.9363 0.64 64160 12066 3 1565.932213 522.9861 PDZ and LIM domain protein 5 OS=Homo sapiens OX=9606 GN=PDLIM5 PE=1 SV=5 8.69 2352.5 - 269637 - - - -2.6387 - 1.922 0.29 - 136.8 1 2 0 -0.0041 15 0 0 0 3.68E+06 5.78E+06 - - - 3.4769 0.9999 221125_WJC_METTL3_EV_vs_WT_F05.12067.12067.2 0.000656 24-Nov R.NVETNQC[160.03]LDNMAR[166.11].K sp|Q10472|GALT1_HUMAN 1 1573.6852 1.62 64161 12067 2 1573.68347 787.8499 Polypeptide N-acetylgalactosaminyltransferase 1 OS=Homo sapiens OX=9606 GN=GALNT1 PE=1 SV=1 4.37 2352.6 - 234711 - - - -1.1279 - 2.457 0.551 - 327.2 1 2 0 -0.0018 13 0 0 0 9.15E+06 5.66E+06 - - - 5.4173 0.9998 221125_WJC_METTL3_EV_vs_WT_F05.12075.12075.3 0.00702 Nov-52 K.FLETESHPSIPPPK[136.11].L "sp|Q15643|TRIPB_HUMAN,tr|H0YJ97|H0YJ97_HUMAN" 2 1585.8232 2.21 64167 12075 3 1585.822878 529.615 Thyroid receptor-interacting protein 11 OS=Homo sapiens OX=9606 GN=TRIP11 PE=1 SV=3 5.4 2353.6 - 1.22E+06 - - - -0.1772 - 1.807 0.398 - 84.8 1 2 0 -0.0003 14 0 0 0 4.87E+07 2.20E+07 - - - 4.5496 0.9041 221125_WJC_METTL3_EV_vs_WT_F05.12076.12076.2 0.00856 12-Aug A.WEDYYKK.Q sp|Q96I24|FUBP3_HUMAN 1 1030.476 3.73 64168 12076 2 1030.476528 516.2453 Far upstream element-binding protein 3 OS=Homo sapiens OX=9606 GN=FUBP3 PE=1 SV=2 6.07 2353.7 - 940265 - - - 0.5153 - 1.459 0.234 - 234.8 1 1 0 0.0005 7 0 0 0 8.01E+06 2.15E+06 - - - 1.9661 1 221125_WJC_METTL3_EV_vs_WT_F05.12080.12080.2 7.01E-12 17/32 R.LPSAQTPNGTDYVASGK.S "sp|Q9Y520|PRC2C_HUMAN,tr|E7EPN9|E7EPN9_HUMAN,tr|H7C5N8|H7C5N8_HUMAN,tr|A0A2R8Y7F4|A0A2R8Y7F4_HUMAN,tr|A0A2R8YET2|A0A2R8YET2_HUMAN" 5 1704.8319 1.88 64172 12080 2 1704.833702 853.4232 Protein PRRC2C OS=Homo sapiens OX=9606 GN=PRRC2C PE=1 SV=4 5.83 2354.2 - 381952 - - - 1.0693 - 3.608 0.698 - 818.1 1 2 0 0.0018 17 0 0 0 6.83E+06 3.63E+06 - - - 7.3505 0.9998 221125_WJC_METTL3_EV_vs_WT_F05.12081.12081.2 4.02E-06 20-Oct K.DQVANSAFVER[166.11].L sp|P07900|HS90A_HUMAN 1 1244.6025 0.42 64173 12081 2 1244.600486 623.3085 Heat shock protein HSP 90-alpha OS=Homo sapiens OX=9606 GN=HSP90AA1 PE=1 SV=5 4.37 2354.4 - 377460 - - - -1.6061 - 2.229 0.566 - 347.5 1 2 0 -0.002 11 0 0 0 2.43E+06 5.82E+06 - - - 5.3892 1 221125_WJC_METTL3_EV_vs_WT_F05.12084.12084.2 1.92E-09 17/30 R.LC[160.03]NLEEGSPGSGTYTR[166.11].H "sp|Q9Y3B2|EXOS1_HUMAN,tr|B1AMU4|B1AMU4_HUMAN,tr|R4GMQ7|R4GMQ7_HUMAN,tr|B1AMU3|B1AMU3_HUMAN,tr|B1AMU7|B1AMU7_HUMAN,tr|R4GNH9|R4GNH9_HUMAN" 6 1749.7867 0.79 64176 12084 2 1749.788723 875.9006 Exosome complex component CSL4 OS=Homo sapiens OX=9606 GN=EXOSC1 PE=1 SV=1 4.53 2354.8 - 272352 - - - 1.1367 - 3.269 0.669 - 932.7 1 2 0 0.002 16 0 0 0 3.40E+06 4.29E+06 - - - 6.8937 0.9998 221125_WJC_METTL3_EV_vs_WT_F05.12085.12085.2 0.000169 18-Sep K.QSPQTSFPYK.L "sp|Q8IWC1|MA7D3_HUMAN,tr|A0A0A0MRP0|A0A0A0MRP0_HUMAN" 2 1181.5717 1.65 64177 12085 2 1181.572204 591.7931 MAP7 domain-containing protein 3 OS=Homo sapiens OX=9606 GN=MAP7D3 PE=1 SV=2 8.59 2354.9 - 243196 - - - 0.4367 - 1.797 0.475 - 352.9 1 2 0 0.0005 10 0 0 0 2.85E+06 1.72E+06 - - - 4.1852 1 221125_WJC_METTL3_EV_vs_WT_F05.12090.12090.3 6.32E-05 15/44 K.LLTHNLLSSHVR.G sp|Q9UI30|TR112_HUMAN 1 1388.7888 1.24 64180 12090 3 1388.790256 463.9369 Multifunctional methyltransferase subunit TRM112-like protein OS=Homo sapiens OX=9606 GN=TRMT112 PE=1 SV=1 9.76 2355.6 - 2.29E+06 - - - 1.0254 - 2.637 0.506 - 405.3 1 2 0 0.0014 12 0 0 0 1.68E+08 1.36E+08 - - - 6.8687 0.9947 221125_WJC_METTL3_EV_vs_WT_F05.12091.12091.3 0.00468 Oct-36 K.LDDDFKEMEK.K sp|Q99961|SH3G1_HUMAN 1 1268.5595 1.6 64181 12091 3 1268.559476 423.8604 Endophilin-A2 OS=Homo sapiens OX=9606 GN=SH3GL1 PE=1 SV=1 4.11 2355.7 - 716648 - - - 0.0055 - 1.542 0.305 - 84.5 1 2 1 0 10 0 0 0 9.95E+06 6.21E+06 - - - 3.2052 0.9299 221125_WJC_METTL3_EV_vs_WT_F05.12092.12092.3 0.00043 Dec-52 K.IK[136.11]ELTSTC[160.03]SPIISK[136.11].P sp|P34932|HSP74_HUMAN 1 1591.8826 0.07 64182 12092 3 1591.885657 531.6348 Heat shock 70 kDa protein 4 OS=Homo sapiens OX=9606 GN=HSPA4 PE=1 SV=4 8.2 2355.8 - 1.11E+06 - - - 1.9235 - 2.264 0.417 - 181.1 1 1 1 0.0031 14 0 0 0 6.20E+05 9.28E+06 - - - 5.3598 0.9997 221125_WJC_METTL3_EV_vs_WT_F05.12093.12093.2 0.0174 13/20 K.VALQDLQTNSK[136.11].L sp|Q9Y6J9|TAF6L_HUMAN 1 1223.6601 1.26 64183 12093 2 1223.661677 612.8373 TAF6-like RNA polymerase II p300\CBP-associated factor-associated factor 65 kDa subunit 6L OS=Homo sapiens OX=9606 GN=TAF6L PE=1 SV=1 5.81 2355.9 - 813267 - - - 1.2757 - 2.535 0.336 - 586.3 1 2 0 0.0016 11 0 0 0 1.39E+07 1.10E+07 - - - 4.0386 0.9995 221125_WJC_METTL3_EV_vs_WT_F05.12094.12094.3 0.00161 Nov-36 K.LDDDFK[136.11]EMEK[136.11].K sp|Q99961|SH3G1_HUMAN 1 1284.5879 1.67 64184 12094 3 1284.589134 429.2032 Endophilin-A2 OS=Homo sapiens OX=9606 GN=SH3GL1 PE=1 SV=1 4.11 2356 - 664971 - - - 0.9848 - 1.829 0.445 - 181.3 1 2 1 0.0013 10 0 0 0 1.04E+07 6.21E+06 - - - 5.2642 0.9999 221125_WJC_METTL3_EV_vs_WT_F05.12095.12095.3 4.04E-05 17/48 R.VSISEGDDK[136.11]IEYR[166.11].A "sp|P22087|FBRL_HUMAN,tr|M0R299|M0R299_HUMAN,tr|M0R0P1|M0R0P1_HUMAN,tr|M0R1H0|M0R1H0_HUMAN,tr|M0QXL5|M0QXL5_HUMAN,tr|M0R2Q4|M0R2Q4_HUMAN,tr|M0R2B0|M0R2B0_HUMAN,tr|M0R2U2|M0R2U2_HUMAN" 8 1527.7536 0.74 64185 12095 3 1527.755023 510.2585 rRNA 2'-O-methyltransferase fibrillarin OS=Homo sapiens OX=9606 GN=FBL PE=1 SV=2 4.32 2356.1 - 529481 - - - 0.9498 - 3.269 0.51 - 516.4 1 2 1 0.0014 13 0 0 0 5.22E+06 7.01E+06 - - - 7.4371 0.9985 221125_WJC_METTL3_EV_vs_WT_F05.12096.12096.2 0.000259 15/26 K.GGVVLKEDALPGQK.T "sp|P35613|BASI_HUMAN,tr|A0A7P0TA85|A0A7P0TA85_HUMAN,tr|A0A7P0TB04|A0A7P0TB04_HUMAN,tr|A0A2R8YDZ0|A0A2R8YDZ0_HUMAN,tr|I3L192|I3L192_HUMAN" 5 1409.7878 1.23 64186 12096 2 1409.789418 705.9012 Basigin OS=Homo sapiens OX=9606 GN=BSG PE=1 SV=2 6.07 2356.3 - 503014 - - - 1.1271 - 2.83 0.508 - 632.6 1 2 1 0.0016 14 0 0 0 4.53E+06 3.69E+06 - - - 5.4031 0.9984 221125_WJC_METTL3_EV_vs_WT_F05.12097.12097.3 0.0115 13/48 R.GIHVEVPPAEAER.L sp|P38117|ETFB_HUMAN 1 1402.7205 0.06 64187 12097 3 1402.722269 468.5808 Electron transfer flavoprotein subunit beta OS=Homo sapiens OX=9606 GN=ETFB PE=1 SV=3 4.75 2356.4 - 1.87E+06 - - - 1.2768 - 1.87 0.26 - 212.8 1 2 0 0.0018 13 0 0 0 5.91E+06 1.01E+08 - - - 3.1353 0.9992 221125_WJC_METTL3_EV_vs_WT_F05.12098.12098.3 0.00615 Oct-52 K.SDPEGENIHAGLLK[136.11].K "sp|Q6P996|PDXD1_HUMAN,tr|H3BND4|H3BND4_HUMAN" 2 1486.7507 2.41 64188 12098 3 1486.751434 496.5909 Pyridoxal-dependent decarboxylase domain-containing protein 1 OS=Homo sapiens OX=9606 GN=PDXDC1 PE=1 SV=2 4.65 2356.5 - 404909 - - - 0.4789 - 1.715 0.312 - 119.8 1 2 0 0.0007 14 0 0 0 8.26E+06 3.43E+06 - - - 3.4518 1 221125_WJC_METTL3_EV_vs_WT_F05.12100.12100.2 2.87E-09 14/30 R.LC[160.03]NLEEGSPGSGTYTR.H "sp|Q9Y3B2|EXOS1_HUMAN,tr|B1AMU4|B1AMU4_HUMAN,tr|R4GMQ7|R4GMQ7_HUMAN,tr|B1AMU3|B1AMU3_HUMAN,tr|B1AMU7|B1AMU7_HUMAN,tr|R4GNH9|R4GNH9_HUMAN" 6 1739.7785 0.79 64190 12100 2 1739.777782 870.8965 Exosome complex component CSL4 OS=Homo sapiens OX=9606 GN=EXOSC1 PE=1 SV=1 4.53 2356.7 - 393260 - - - -0.392 - 3.006 0.654 - 550.4 1 2 0 -0.0007 16 0 0 0 3.40E+06 4.29E+06 - - - 6.5771 0.9999 221125_WJC_METTL3_EV_vs_WT_F05.12102.12102.2 4.84E-08 22-Oct R.AQPSASLGVGYR.T sp|Q96PK6|RBM14_HUMAN 1 1204.62 2.35 64192 12102 2 1204.621687 603.3173 RNA-binding protein 14 OS=Homo sapiens OX=9606 GN=RBM14 PE=1 SV=2 8.79 2357 - 346935 - - - 1.3706 - 2.187 0.593 - 332.4 1 2 0 0.0017 12 0 0 0 5.12E+06 2.18E+06 - - - 5.4794 0.9999 221125_WJC_METTL3_EV_vs_WT_F05.12103.12103.3 5.98E-05 15/48 R.VSISEGDDKIEYR.A "sp|P22087|FBRL_HUMAN,tr|M0R299|M0R299_HUMAN,tr|M0R0P1|M0R0P1_HUMAN,tr|M0R1H0|M0R1H0_HUMAN,tr|M0QXL5|M0QXL5_HUMAN,tr|M0R2Q4|M0R2Q4_HUMAN,tr|M0R2B0|M0R2B0_HUMAN,tr|M0R2U2|M0R2U2_HUMAN" 8 1509.7311 0.74 64193 12103 3 1509.730292 504.251 rRNA 2'-O-methyltransferase fibrillarin OS=Homo sapiens OX=9606 GN=FBL PE=1 SV=2 4.32 2357.1 - 345962 - - - -0.5365 - 2.78 0.553 - 386 1 2 1 -0.0008 13 0 0 0 5.22E+06 7.01E+06 - - - 7.4773 1 221125_WJC_METTL3_EV_vs_WT_F05.12105.12105.2 3.25E-10 13/32 R.LPSAQTPNGTDYVASGK[136.11].S "sp|Q9Y520|PRC2C_HUMAN,tr|E7EPN9|E7EPN9_HUMAN,tr|H7C5N8|H7C5N8_HUMAN,tr|A0A2R8Y7F4|A0A2R8Y7F4_HUMAN,tr|A0A2R8YET2|A0A2R8YET2_HUMAN" 5 1712.8461 1.88 64195 12105 2 1712.84459 857.4303 Protein PRRC2C OS=Homo sapiens OX=9606 GN=PRRC2C PE=1 SV=4 5.83 2357.4 - 305809 - - - -0.8693 - 3.165 0.671 - 411 1 2 0 -0.0015 17 0 0 0 6.83E+06 3.63E+06 - - - 6.8292 0.9999 221125_WJC_METTL3_EV_vs_WT_F05.12110.12110.2 0.00105 20-Nov R.C[160.03]SEQPSISDIK.E "sp|Q14527|HLTF_HUMAN,tr|A0A0C4DGA6|A0A0C4DGA6_HUMAN" 2 1262.5813 1.73 64199 12110 2 1262.580637 632.2979 Helicase-like transcription factor OS=Homo sapiens OX=9606 GN=HLTF PE=1 SV=2 4.37 2358 - 505770 - - - -0.499 - 2.244 0.539 - 506.5 1 2 0 -0.0006 11 0 0 0 8.47E+06 4.90E+06 - - - 5.2084 1 221125_WJC_METTL3_EV_vs_WT_F05.12112.12112.3 1.79E-07 17/44 K.LLTHNLLSSHVR[166.11].G sp|Q9UI30|TR112_HUMAN 1 1398.7971 1.24 64200 12112 3 1398.799864 467.273 Multifunctional methyltransferase subunit TRM112-like protein OS=Homo sapiens OX=9606 GN=TRMT112 PE=1 SV=1 9.76 2358.2 - 9.46E+06 - - - 1.9746 - 3.257 0.437 - 551.9 1 2 0 0.0028 12 0 0 0 1.68E+08 1.36E+08 - - - 6.6844 0.9997 221125_WJC_METTL3_EV_vs_WT_F05.12113.12113.3 0.00288 Dec-40 K.EVSSSFDHVIK.E "sp|Q9Y6C9|MTCH2_HUMAN,tr|E9PIE4|E9PIE4_HUMAN" 2 1246.6194 0.8 64201 12113 3 1246.621398 416.5471 Mitochondrial carrier homolog 2 OS=Homo sapiens OX=9606 GN=MTCH2 PE=1 SV=1 5.32 2358.3 - 1.57E+06 - - - 1.6292 - 1.92 0.388 - 151.9 1 2 0 0.002 11 0 0 0 1.09E+07 1.37E+07 - - - 4.7184 0.9999 221125_WJC_METTL3_EV_vs_WT_F05.12114.12114.3 4.88E-08 21/52 K.GGVVLKEDALPGQK.T "sp|P35613|BASI_HUMAN,tr|A0A7P0TA85|A0A7P0TA85_HUMAN,tr|A0A7P0TB04|A0A7P0TB04_HUMAN,tr|A0A2R8YDZ0|A0A2R8YDZ0_HUMAN,tr|I3L192|I3L192_HUMAN" 5 1409.7878 1.25 64202 12114 3 1409.790053 470.9366 Basigin OS=Homo sapiens OX=9606 GN=BSG PE=1 SV=2 6.07 2358.3 - 5.27E+06 - - - 1.5775 - 3.426 0.572 - 575.6 1 2 1 0.0022 14 0 0 0 3.83E+07 3.07E+07 - - - 8.1891 0.9998 221125_WJC_METTL3_EV_vs_WT_F05.12115.12115.2 0.000134 20-Oct K.VALQDLQTNSK.L sp|Q9Y6J9|TAF6L_HUMAN 1 1215.6459 1.26 64203 12115 2 1215.647633 608.8302 TAF6-like RNA polymerase II p300\CBP-associated factor-associated factor 65 kDa subunit 6L OS=Homo sapiens OX=9606 GN=TAF6L PE=1 SV=1 5.81 2358.4 - 1.62E+06 - - - 1.4124 - 2.25 0.46 - 360.2 1 2 0 0.0017 11 0 0 0 1.40E+07 1.10E+07 - - - 4.6318 1 221125_WJC_METTL3_EV_vs_WT_F05.12117.12117.3 3.13E-05 20/56 K.EVESMGAHLNAYSTR[166.11].E sp|P31930|QCR1_HUMAN 1 1673.7707 1.34 64205 12117 3 1673.773922 558.9308 "Cytochrome b-c1 complex subunit 1, mitochondrial OS=Homo sapiens OX=9606 GN=UQCRC1 PE=1 SV=3" 5.4 2358.6 - 911254 - - - 1.9316 - 3.147 0.562 - 593.2 1 2 0 0.0032 15 0 0 0 9.50E+06 7.08E+06 - - - 7.7964 0.93 221125_WJC_METTL3_EV_vs_WT_F05.12118.12118.3 0.201 14/40 L.LTHNLLSSHVR.G sp|Q9UI30|TR112_HUMAN 1 1275.7048 0.77 64206 12118 3 1275.709543 426.2422 Multifunctional methyltransferase subunit TRM112-like protein OS=Homo sapiens OX=9606 GN=TRMT112 PE=1 SV=1 9.76 2358.7 - 887461 - - - 3.743 - 2.619 0.345 - 344.9 1 1 0 0.0048 11 0 0 0 1.88E+07 2.42E+07 - - - 5.1202 0.9997 221125_WJC_METTL3_EV_vs_WT_F05.12121.12121.3 0.00364 Sep-44 K.YSHEVLSEENFK[136.11].V "sp|Q7Z2W4|ZCCHV_HUMAN,tr|C9J6P4|C9J6P4_HUMAN" 2 1488.6976 1.16 64209 12121 3 1488.699712 497.2398 Zinc finger CCCH-type antiviral protein 1 OS=Homo sapiens OX=9606 GN=ZC3HAV1 PE=1 SV=3 4.75 2359 - 728049 - - - 1.4026 - 1.848 0.374 - 113.6 1 2 0 0.0021 12 0 0 0 9.65E+06 8.33E+06 - - - 4.4114 0.8238 221125_WJC_METTL3_EV_vs_WT_F05.12125.12125.3 0.0127 Sep-40 T.IHLPSPVTAQK[136.11].Y sp|P13639|EF2_HUMAN 1 1197.6961 0.45 64213 12125 3 1197.69729 400.2393 Elongation factor 2 OS=Homo sapiens OX=9606 GN=EEF2 PE=1 SV=4 8.76 2359.5 - 223614 - - - 0.9869 - 1.619 0.267 - 115.3 1 1 0 0.0012 11 0 0 0 1.02E+06 2.26E+06 - - - 2.8852 0.9989 221125_WJC_METTL3_EV_vs_WT_F05.12127.12127.2 0.000845 20-Aug K.EVSSSFDHVIK[136.11].E "sp|Q9Y6C9|MTCH2_HUMAN,tr|E9PIE4|E9PIE4_HUMAN" 2 1254.6336 1 64215 12127 2 1254.631201 628.3241 Mitochondrial carrier homolog 2 OS=Homo sapiens OX=9606 GN=MTCH2 PE=1 SV=1 5.32 2359.8 - 215449 - - - -1.8858 - 1.509 0.381 - 143.9 1 2 0 -0.0024 11 0 0 0 2.98E+06 2.99E+06 - - - 2.9674 0.9998 221125_WJC_METTL3_EV_vs_WT_F05.12128.12128.2 0.000139 22-Jul R.GGDFSSSDFQSR.D sp|P78332|RBM6_HUMAN 1 1288.532 1.27 64216 12128 2 1288.532191 645.2733 RNA-binding protein 6 OS=Homo sapiens OX=9606 GN=RBM6 PE=1 SV=5 4.21 2359.9 - 155422 - - - 0.1412 - 1.423 0.546 - 140.4 1 2 0 0.0002 12 0 0 0 1.35E+06 1.06E+06 - - - 4.0019 0.9993 221125_WJC_METTL3_EV_vs_WT_F05.12131.12131.2 0.000614 26-Nov R.DQDLEPGAPSMGAK[136.11].S sp|P07814|SYEP_HUMAN 1 1422.654 0.85 64218 12131 2 1422.657689 712.3343 Bifunctional glutamate\proline--tRNA ligase OS=Homo sapiens OX=9606 GN=EPRS1 PE=1 SV=5 4.03 2360.3 - 385468 - - - 2.5621 - 2.005 0.437 - 297.1 1 2 0 0.0036 14 0 0 0 1.05E+07 1.23E+07 - - - 4.0132 0.9999 221125_WJC_METTL3_EV_vs_WT_F05.12133.12133.3 5.13E-05 16/52 K.GGVVLK[136.11]EDALPGQK[136.11].T "sp|P35613|BASI_HUMAN,tr|A0A7P0TA85|A0A7P0TA85_HUMAN,tr|A0A7P0TB04|A0A7P0TB04_HUMAN,tr|A0A2R8YDZ0|A0A2R8YDZ0_HUMAN,tr|I3L192|I3L192_HUMAN" 5 1425.8162 1.25 64219 12133 3 1425.817834 476.2794 Basigin OS=Homo sapiens OX=9606 GN=BSG PE=1 SV=2 6.07 2360.5 - 2.61E+06 - - - 1.1257 - 2.943 0.591 - 310.5 1 2 1 0.0016 14 0 0 0 3.84E+07 3.07E+07 - - - 7.9972 1 221125_WJC_METTL3_EV_vs_WT_F05.12134.12134.2 1.64E-05 20-Nov S.GSGSGTDFTLK.L "sp|A2NJV5|KV229_HUMAN,sp|A0A087WW87|KV240_HUMAN,sp|P06310|KV230_HUMAN,sp|A0A075B6S2|KVD29_HUMAN,sp|P01614|KVD40_HUMAN,sp|P01615|KVD28_HUMAN,sp|A0A075B6S6|KVD30_HUMAN,sp|A0A075B6P5|KV228_HUMAN,sp|A0A0A0MRZ7|KVD26_HUMAN" 9 1068.5088 14.3 64220 12134 2 1068.510517 535.2617 Immunoglobulin kappa variable 2-29 OS=Homo sapiens OX=9606 GN=IGKV2-29 PE=3 SV=2 5.84 2360.6 - 2.24E+06 - - - 1.65 - 2.395 0.591 - 461.1 1 1 0 0.0018 11 0 0 0 1.97E+07 1.38E+06 - - - 5.7683 0.9992 221125_WJC_METTL3_EV_vs_WT_F05.12136.12136.3 0.00134 Oct-56 K.DVDSAYMNKVELQAK.V sp|P12035|K2C3_HUMAN 1 1709.8294 12.09 64222 12136 3 1709.832198 570.9504 "Keratin, type II cytoskeletal 3 OS=Homo sapiens OX=9606 GN=KRT3 PE=1 SV=3" 4.56 2360.7 - 1.16E+06 - - - 1.6154 - 1.728 0.455 - 68.5 1 2 1 0.0028 15 0 0 0 8.60E+06 7.11E+05 - - - 5.0393 0.9994 221125_WJC_METTL3_EV_vs_WT_F05.12137.12137.3 0.00448 Aug-44 K.YSHEVLSEENFK.V "sp|Q7Z2W4|ZCCHV_HUMAN,tr|C9J6P4|C9J6P4_HUMAN" 2 1480.6834 1.13 64223 12137 3 1480.686045 494.5684 Zinc finger CCCH-type antiviral protein 1 OS=Homo sapiens OX=9606 GN=ZC3HAV1 PE=1 SV=3 4.75 2360.8 - 1.02E+06 - - - 1.7701 - 1.904 0.334 - 95.7 1 2 0 0.0026 12 0 0 0 9.65E+06 8.57E+06 - - - 4.048 0.9978 221125_WJC_METTL3_EV_vs_WT_F05.12140.12140.3 4.30E-05 14/36 L.THNLLSSHVR[166.11].G sp|Q9UI30|TR112_HUMAN 1 1172.629 0.96 64226 12140 3 1172.629998 391.8836 Multifunctional methyltransferase subunit TRM112-like protein OS=Homo sapiens OX=9606 GN=TRMT112 PE=1 SV=1 9.47 2361.1 - 815778 - - - 0.8733 - 2.809 0.495 - 371.2 1 1 0 0.001 10 0 0 0 4.60E+06 4.82E+06 - - - 7.0748 0.9998 221125_WJC_METTL3_EV_vs_WT_F05.12141.12141.2 9.24E-05 15/22 K.LLTHNLLSSHVR.G sp|Q9UI30|TR112_HUMAN 1 1388.7888 1.2 64227 12141 2 1388.792146 695.4017 Multifunctional methyltransferase subunit TRM112-like protein OS=Homo sapiens OX=9606 GN=TRMT112 PE=1 SV=1 9.76 2361.3 - 570154 - - - 2.3863 - 2.794 0.536 - 978.2 1 2 0 0.0033 12 0 0 0 6.07E+06 5.04E+06 - - - 5.7023 0.9998 221125_WJC_METTL3_EV_vs_WT_F05.12142.12142.3 0.00021 Oct-36 R.SQVEPLFTHR[166.11].G sp|Q6P4I2|WDR73_HUMAN 1 1222.6334 0.45 64228 12142 3 1222.633312 408.5517 WD repeat-containing protein 73 OS=Homo sapiens OX=9606 GN=WDR73 PE=1 SV=1 6.47 2361.4 - 557924 - - - -0.0646 - 1.829 0.376 - 155.3 1 2 0 -0.0001 10 0 0 0 1.74E+06 3.83E+06 - - - 4.4953 0.9995 221125_WJC_METTL3_EV_vs_WT_F05.12147.12147.2 4.16E-08 13/26 K.SGELNGDQVSLGTK[136.11].K "sp|Q96C57|CSTOS_HUMAN,tr|G5EA44|G5EA44_HUMAN,tr|E7ENF1|E7ENF1_HUMAN,tr|F5H8B7|F5H8B7_HUMAN,tr|F5H7W8|F5H7W8_HUMAN" 5 1411.7034 0.95 64233 12147 2 1411.70832 706.859 Protein CUSTOS OS=Homo sapiens OX=9606 GN=CUSTOS PE=1 SV=2 4.37 2362 - 411959 - - - 3.4582 - 2.564 0.568 - 599.9 1 2 0 0.0049 14 0 0 0 2.35E+06 2.46E+06 - - - 5.5975 0.9999 221125_WJC_METTL3_EV_vs_WT_F05.12148.12148.2 0.00195 26-Dec K.SGELNGDQVSLGTK.K "sp|Q96C57|CSTOS_HUMAN,tr|G5EA44|G5EA44_HUMAN,tr|E7ENF1|E7ENF1_HUMAN,tr|F5H8B7|F5H8B7_HUMAN,tr|F5H7W8|F5H7W8_HUMAN" 5 1403.6892 0.95 64234 12148 2 1403.687419 702.8519 Protein CUSTOS OS=Homo sapiens OX=9606 GN=CUSTOS PE=1 SV=2 4.37 2362.1 - 320675 - - - -1.2959 - 2.641 0.491 - 506.9 1 2 0 -0.0018 14 0 0 0 2.35E+06 2.46E+06 - - - 5.104 0.9964 221125_WJC_METTL3_EV_vs_WT_F05.12151.12151.2 0.00023 20-Aug R.C[160.03]SEQPSISDIK[136.11].E "sp|Q14527|HLTF_HUMAN,tr|A0A0C4DGA6|A0A0C4DGA6_HUMAN" 2 1270.5955 1.27 64237 12151 2 1270.600908 636.305 Helicase-like transcription factor OS=Homo sapiens OX=9606 GN=HLTF PE=1 SV=2 4.37 2362.5 - 183079 - - - 4.2822 - 1.698 0.416 - 248.1 1 2 0 0.0054 11 0 0 0 2.00E+07 1.57E+07 - - - 3.5442 0.9997 221125_WJC_METTL3_EV_vs_WT_F05.12152.12152.2 6.02E-05 24-Aug R.SIPLDEGEDEAQR.R "sp|Q14204|DYHC1_HUMAN,tr|A0A7P0T8N2|A0A7P0T8N2_HUMAN,tr|A0A7P0T9C4|A0A7P0T9C4_HUMAN,tr|A0A7P0TBJ7|A0A7P0TBJ7_HUMAN,tr|A0A804HHY6|A0A804HHY6_HUMAN,tr|A0A7P0T9K2|A0A7P0T9K2_HUMAN,tr|A0A7P0TB64|A0A7P0TB64_HUMAN,tr|A0A2R8Y706|A0A2R8Y706_HUMAN,tr|A0A7P0T916|A0A7P0T916_HUMAN,tr|A0A7P0TB75|A0A7P0TB75_HUMAN,tr|A0A7P0T8W5|A0A7P0T8W5_HUMAN,tr|A0A7P0TAF3|A0A7P0TAF3_HUMAN,tr|A0A7P0T9F1|A0A7P0T9F1_HUMAN,tr|A0A7P0TAW9|A0A7P0TAW9_HUMAN,tr|A0A2R8YGC7|A0A2R8YGC7_HUMAN,tr|A0A7P0TA13|A0A7P0TA13_HUMAN,tr|A0A7P0TAV5|A0A7P0TAV5_HUMAN,tr|A0A7P0T7V5|A0A7P0T7V5_HUMAN,tr|A0A7P0T9R4|A0A7P0T9R4_HUMAN,tr|A0A2R8Y5T0|A0A2R8Y5T0_HUMAN,tr|A0A7P0T990|A0A7P0T990_HUMAN,tr|A0A7P0T942|A0A7P0T942_HUMAN,tr|A0A2R8YFZ7|A0A2R8YFZ7_HUMAN,tr|A0A7P0T825|A0A7P0T825_HUMAN,tr|A0A2R8Y6H2|A0A2R8Y6H2_HUMAN,tr|A0A7P0TAM4|A0A7P0TAM4_HUMAN" 26 1457.6634 2.16 64238 12152 2 1457.663254 729.839 Cytoplasmic dynein 1 heavy chain 1 OS=Homo sapiens OX=9606 GN=DYNC1H1 PE=1 SV=5 3.83 2362.6 - 180652 - - - -0.1118 - 1.581 0.478 - 124.9 1 2 0 -0.0002 13 0 0 0 5.26E+06 2.43E+06 - - - 3.7471 0.9991 221125_WJC_METTL3_EV_vs_WT_F05.12156.12156.2 0.000249 13/22 K.INSWVESQTNEK.L "sp|P48594|SPB4_HUMAN,sp|P29508|SPB3_HUMAN,tr|C9JZ65|C9JZ65_HUMAN,tr|H0Y5H9|H0Y5H9_HUMAN" 4 1433.6787 45.28 64241 12156 2 1433.684303 717.8466 Serpin B4 OS=Homo sapiens OX=9606 GN=SERPINB4 PE=1 SV=2 4.53 2363.1 - 1.35E+06 - - - 3.927 - 2.667 0.497 - 851.6 1 2 0 0.0056 12 0 0 0 7.28E+07 1.61E+06 - - - 5.2911 0.9985 221125_WJC_METTL3_EV_vs_WT_F05.12158.12158.3 4.90E-06 14/52 R.VLTVINQTQK[136.11]ENLR[166.11].K "sp|P42766|RL35_HUMAN,tr|F2Z388|F2Z388_HUMAN" 2 1672.9591 0.59 64243 12158 3 1672.96117 558.6603 60S ribosomal protein L35 OS=Homo sapiens OX=9606 GN=RPL35 PE=1 SV=2 8.72 2363.2 - 799570 - - - 1.2439 - 2.757 0.279 - 235.2 1 2 1 0.0021 14 0 0 0 2.70E+06 4.56E+06 - - - 4.3451 0.9997 221125_WJC_METTL3_EV_vs_WT_F05.12159.12159.3 1.09E-06 19/52 K.VAGIESHSELQISR.Q "sp|Q14980|NUMA1_HUMAN,tr|A0A087WY61|A0A087WY61_HUMAN" 2 1524.7896 1.26 64244 12159 3 1524.797886 509.2705 Nuclear mitotic apparatus protein 1 OS=Homo sapiens OX=9606 GN=NUMA1 PE=1 SV=2 5.4 2363.3 - 596228 - - - 5.4211 - 3.211 0.531 - 648.8 1 2 0 0.0083 14 0 0 0 4.77E+06 3.78E+06 - - - 7.5581 0.9998 221125_WJC_METTL3_EV_vs_WT_F05.12161.12161.2 1.33E-06 14/22 K.LLTHNLLSSHVR[166.11].G sp|Q9UI30|TR112_HUMAN 1 1398.7971 1.2 64246 12161 2 1398.798818 700.4058 Multifunctional methyltransferase subunit TRM112-like protein OS=Homo sapiens OX=9606 GN=TRMT112 PE=1 SV=1 9.76 2363.6 - 525575 - - - 1.2268 - 2.579 0.411 - 827 1 2 0 0.0017 12 0 0 0 6.07E+06 5.04E+06 - - - 4.5689 0.9999 221125_WJC_METTL3_EV_vs_WT_F05.12162.12162.3 7.21E-07 18/52 R.VLTVINQTQKENLR.K "sp|P42766|RL35_HUMAN,tr|F2Z388|F2Z388_HUMAN" 2 1654.9366 0.59 64247 12162 3 1654.938742 552.6528 60S ribosomal protein L35 OS=Homo sapiens OX=9606 GN=RPL35 PE=1 SV=2 8.72 2363.7 - 467142 - - - 1.2828 - 3.307 0.587 - 485 1 2 1 0.0021 14 0 0 0 2.70E+06 4.56E+06 - - - 8.2624 0.9998 221125_WJC_METTL3_EV_vs_WT_F05.12163.12163.2 6.60E-06 24-Nov K.NTFSSGSDLNAVK.S "sp|Q9NTX5|ECHD1_HUMAN,tr|J3KP84|J3KP84_HUMAN,tr|E9PPG7|E9PPG7_HUMAN,tr|H0Y5L2|H0Y5L2_HUMAN,tr|H0Y525|H0Y525_HUMAN,tr|E9PJS8|E9PJS8_HUMAN,tr|E9PLY6|E9PLY6_HUMAN,tr|E9PRU6|E9PRU6_HUMAN,tr|F2Z2D6|F2Z2D6_HUMAN" 9 1338.6416 0.45 64248 12163 2 1338.643893 670.3281 Ethylmalonyl-CoA decarboxylase OS=Homo sapiens OX=9606 GN=ECHDC1 PE=1 SV=2 5.84 2363.8 - 408126 - - - 1.7436 - 2.434 0.578 - 332.5 1 2 0 0.0023 13 0 0 0 2.06E+06 4.59E+06 - - - 5.5924 0.981 221125_WJC_METTL3_EV_vs_WT_F05.12166.12166.2 9.03E-05 18-Oct L.THNLLSSHVR.G sp|Q9UI30|TR112_HUMAN 1 1162.6207 1.95 64251 12166 2 1162.6233 582.3176 Multifunctional methyltransferase subunit TRM112-like protein OS=Homo sapiens OX=9606 GN=TRMT112 PE=1 SV=1 9.47 2364.2 - 240776 - - - 2.2329 - 1.995 0.529 - 377.4 1 1 0 0.0026 10 0 0 0 1.12E+06 5.71E+05 - - - 4.8752 1 221125_WJC_METTL3_EV_vs_WT_F05.12168.12168.2 2.96E-09 16/20 K.HPENYDLATLK.W "sp|P78347|GTF2I_HUMAN,sp|Q86UP8|GTD2A_HUMAN,sp|Q6EKJ0|GTD2B_HUMAN,tr|A0A494C1N8|A0A494C1N8_HUMAN,tr|A0A087WW90|A0A087WW90_HUMAN,tr|A0A0D9SF80|A0A0D9SF80_HUMAN,tr|A0A494C0I1|A0A494C0I1_HUMAN,tr|A0A494C1K3|A0A494C1K3_HUMAN" 8 1299.6459 -1 64253 12168 2 1299.643487 650.8302 General transcription factor II-I OS=Homo sapiens OX=9606 GN=GTF2I PE=1 SV=2 5.32 2364.5 - 219679 - - - -1.869 - 3.092 0.639 - 732.3 1 2 0 -0.0024 11 0 0 0 0.00E+00 0.00E+00 - - - 6.8136 0.9977 221125_WJC_METTL3_EV_vs_WT_F05.12169.12169.2 0.00288 20-Aug K.R[166.11]NIYLMDTSGK[136.11].V "sp|P27694|RFA1_HUMAN,tr|I3L4R8|I3L4R8_HUMAN" 2 1314.6721 0.12 64254 12169 2 1314.676651 658.3433 Replication protein A 70 kDa DNA-binding subunit OS=Homo sapiens OX=9606 GN=RPA1 PE=1 SV=2 8.59 2364.6 - 193582 - - - 3.4685 - 1.801 0.375 - 198 1 2 0 0.0046 11 0 0 0 1.69E+06 1.36E+07 - - - 3.4009 0.9996 221125_WJC_METTL3_EV_vs_WT_F05.12171.12171.2 0.0043 26-Sep R.EALENANTNTEVLK[136.11].N sp|Q9H444|CHM4B_HUMAN 1 1552.7824 1.37 64256 12171 2 1552.784076 777.3985 Charged multivesicular body protein 4b OS=Homo sapiens OX=9606 GN=CHMP4B PE=1 SV=1 4.25 2364.9 - 184748 - - - 1.069 - 1.981 0.379 - 219.7 1 2 0 0.0017 14 0 0 0 2.68E+06 1.96E+06 - - - 3.5552 0.9999 221125_WJC_METTL3_EV_vs_WT_F05.12172.12172.2 3.84E-07 26-Dec R.EALENANTNTEVLK.N sp|Q9H444|CHM4B_HUMAN 1 1544.7682 1.37 64257 12172 2 1544.769002 773.3914 Charged multivesicular body protein 4b OS=Homo sapiens OX=9606 GN=CHMP4B PE=1 SV=1 4.25 2365 - 156268 - - - 0.5088 - 2.501 0.546 - 541 1 2 0 0.0008 14 0 0 0 2.68E+06 1.96E+06 - - - 5.3739 0.9949 221125_WJC_METTL3_EV_vs_WT_F05.12173.12173.2 0.00773 22-Oct K.GQSDVLLSTTSK[136.11].E sp|Q6ULP2|AFTIN_HUMAN 1 1242.6547 6.07 64258 12173 2 1242.658862 622.3346 Aftiphilin OS=Homo sapiens OX=9606 GN=AFTPH PE=1 SV=3 5.84 2365.1 - 146101 - - - 3.3525 - 1.394 0.35 - 158.3 1 2 0 0.0042 12 0 0 0 5.12E+06 8.44E+05 - - - 2.4988 0.9999 221125_WJC_METTL3_EV_vs_WT_F05.12177.12177.3 0.000563 15/40 R.SLGTADVHFER.K "sp|Q86V81|THOC4_HUMAN,tr|E9PB61|E9PB61_HUMAN" 2 1230.5993 0.73 64260 12177 3 1230.600054 411.207 THO complex subunit 4 OS=Homo sapiens OX=9606 GN=ALYREF PE=1 SV=3 5.3 2365.7 - 7.50E+06 - - - 0.6127 - 2.329 0.36 - 263.6 1 2 0 0.0008 11 0 0 0 1.76E+09 2.43E+09 - - - 4.9552 1 221125_WJC_METTL3_EV_vs_WT_F05.12179.12179.3 8.33E-08 Oct-40 K.HPENYDLATLK.W "sp|P78347|GTF2I_HUMAN,sp|Q86UP8|GTD2A_HUMAN,sp|Q6EKJ0|GTD2B_HUMAN,tr|A0A494C1N8|A0A494C1N8_HUMAN,tr|A0A087WW90|A0A087WW90_HUMAN,tr|A0A0D9SF80|A0A0D9SF80_HUMAN,tr|A0A494C0I1|A0A494C0I1_HUMAN,tr|A0A494C1K3|A0A494C1K3_HUMAN" 8 1299.6459 1.55 64262 12179 3 1299.645495 434.2226 General transcription factor II-I OS=Homo sapiens OX=9606 GN=GTF2I PE=1 SV=2 5.32 2365.8 - 2.20E+06 - - - -0.3239 - 2.168 0.62 - 148.4 1 2 0 -0.0004 11 0 0 0 5.84E+08 3.77E+08 - - - 7.6505 0.9907 221125_WJC_METTL3_EV_vs_WT_F05.12180.12180.2 0.000745 16-Nov L.GTADVHFER[166.11].K "sp|Q86V81|THOC4_HUMAN,tr|E9PB61|E9PB61_HUMAN" 2 1040.4915 0.73 64263 12180 2 1040.491056 521.253 THO complex subunit 4 OS=Homo sapiens OX=9606 GN=ALYREF PE=1 SV=3 5.32 2365.9 - 2.20E+06 - - - -0.4056 - 2.023 0.456 - 710.8 1 1 0 -0.0004 9 0 0 0 2.67E+08 3.66E+08 - - - 4.4473 1 221125_WJC_METTL3_EV_vs_WT_F05.12181.12181.3 0.000149 Dec-40 K.HPENYDLATLK[136.11].W "sp|P78347|GTF2I_HUMAN,sp|Q86UP8|GTD2A_HUMAN,sp|Q6EKJ0|GTD2B_HUMAN,tr|A0A494C1N8|A0A494C1N8_HUMAN,tr|A0A087WW90|A0A087WW90_HUMAN,tr|A0A0D9SF80|A0A0D9SF80_HUMAN,tr|A0A494C0I1|A0A494C0I1_HUMAN,tr|A0A494C1K3|A0A494C1K3_HUMAN" 8 1307.6601 1.55 64264 12181 3 1307.660792 436.894 General transcription factor II-I OS=Homo sapiens OX=9606 GN=GTF2I PE=1 SV=2 5.32 2365.9 - 1.74E+06 - - - 0.517 - 2.388 0.503 - 242.5 1 2 0 0.0007 11 0 0 0 5.85E+08 3.77E+08 - - - 6.6206 1 221125_WJC_METTL3_EV_vs_WT_F05.12182.12182.2 3.87E-10 16/20 K.HPENYDLATLK[136.11].W "sp|P78347|GTF2I_HUMAN,sp|Q86UP8|GTD2A_HUMAN,sp|Q6EKJ0|GTD2B_HUMAN,tr|A0A494C1N8|A0A494C1N8_HUMAN,tr|A0A087WW90|A0A087WW90_HUMAN,tr|A0A0D9SF80|A0A0D9SF80_HUMAN,tr|A0A494C0I1|A0A494C0I1_HUMAN,tr|A0A494C1K3|A0A494C1K3_HUMAN" 8 1307.6601 1.51 64265 12182 2 1307.66141 654.8373 General transcription factor II-I OS=Homo sapiens OX=9606 GN=GTF2I PE=1 SV=2 5.32 2366 - 1.54E+06 - - - 0.9896 - 3.138 0.644 - 828.1 1 2 0 0.0013 11 0 0 0 5.84E+08 3.88E+08 - - - 6.8908 1 221125_WJC_METTL3_EV_vs_WT_F05.12183.12183.3 6.93E-08 20/56 K.C[160.03]VLPEEDSGELAK[136.11]PK[136.11].L sp|Q9Y3F4|STRAP_HUMAN 1 1686.8469 0.84 64266 12183 3 1686.847229 563.2896 Serine-threonine kinase receptor-associated protein OS=Homo sapiens OX=9606 GN=STRAP PE=1 SV=1 4.41 2366.1 - 1.44E+06 - - - 0.1731 - 3.44 0.615 - 465 1 2 0 0.0003 15 0 0 0 2.07E+07 2.47E+07 - - - 8.6204 1 221125_WJC_METTL3_EV_vs_WT_F05.12184.12184.3 7.55E-07 21/56 K.C[160.03]VLPEEDSGELAKPK.L sp|Q9Y3F4|STRAP_HUMAN 1 1670.8185 0.84 64267 12184 3 1670.819541 557.9468 Serine-threonine kinase receptor-associated protein OS=Homo sapiens OX=9606 GN=STRAP PE=1 SV=1 4.41 2366.2 - 1.42E+06 - - - 0.6009 - 3.501 0.673 - 383.2 1 2 0 0.001 15 0 0 0 2.07E+07 2.46E+07 - - - 9.3127 0.9999 221125_WJC_METTL3_EV_vs_WT_F05.12185.12185.3 0.00018 Dec-48 K.QIATLHAQVADMK.K sp|P35579|MYH9_HUMAN 1 1424.7446 0.96 64268 12185 3 1424.743908 475.9221 Myosin-9 OS=Homo sapiens OX=9606 GN=MYH9 PE=1 SV=4 6.74 2366.2 - 1.25E+06 - - - -0.4745 - 2.264 0.41 - 227.1 1 2 0 -0.0007 13 0 0 0 9.73E+06 1.02E+07 - - - 5.3264 0.9999 221125_WJC_METTL3_EV_vs_WT_F05.12186.12186.2 5.88E-06 14/20 R.SLGTADVHFER[166.11].K "sp|Q86V81|THOC4_HUMAN,tr|E9PB61|E9PB61_HUMAN" 2 1240.6076 0.67 64269 12186 2 1240.608179 621.3111 THO complex subunit 4 OS=Homo sapiens OX=9606 GN=ALYREF PE=1 SV=3 5.3 2366.4 - 1.25E+06 - - - 0.4909 - 2.535 0.56 - 532.5 1 2 0 0.0006 11 0 0 0 1.54E+08 2.29E+08 - - - 5.6934 0.9999 221125_WJC_METTL3_EV_vs_WT_F05.12187.12187.3 6.13E-06 13/40 R.DFPYEEDSRPR.S "sp|Q96I25|SPF45_HUMAN,tr|Q5W012|Q5W012_HUMAN,tr|Q5W010|Q5W010_HUMAN,tr|Q5W011|Q5W011_HUMAN,tr|H0Y6J6|H0Y6J6_HUMAN" 5 1409.6212 2.74 64270 12187 3 1409.621811 470.881 Splicing factor 45 OS=Homo sapiens OX=9606 GN=RBM17 PE=1 SV=1 4.32 2366.5 - 666269 - - - 0.4632 - 2.024 0.445 - 251.6 1 2 0 0.0007 11 0 0 0 1.31E+07 4.80E+06 - - - 5.5041 0.9995 221125_WJC_METTL3_EV_vs_WT_F05.12190.12190.2 0.00396 16-Aug R.DILQDVHDK.L sp|Q92621|NU205_HUMAN 1 1081.5404 1.58 64273 12190 2 1081.53986 541.7775 Nuclear pore complex protein Nup205 OS=Homo sapiens OX=9606 GN=NUP205 PE=1 SV=3 4.41 2366.8 - 399064 - - - -0.4882 - 1.71 0.342 - 181 1 2 0 -0.0005 9 0 0 0 2.93E+06 1.86E+06 - - - 3.119 0.9949 221125_WJC_METTL3_EV_vs_WT_F05.12192.12192.3 0.0304 Oct-52 K.SVAHGQAPEMPLVK.K "sp|Q1ED39|KNOP1_HUMAN,tr|H3BMC9|H3BMC9_HUMAN" 2 1462.7602 3.95 64275 12192 3 1462.760302 488.594 Lysine-rich nucleolar protein 1 OS=Homo sapiens OX=9606 GN=KNOP1 PE=1 SV=1 6.47 2367 - 359285 - - - 0.0465 - 1.888 0.179 - 118.8 1 2 0 0.0001 14 0 0 0 1.50E+07 3.79E+06 - - - 2.2246 0.9998 221125_WJC_METTL3_EV_vs_WT_F05.12194.12194.3 0.000806 Dec-36 R.VPAPFK[136.11]PITR[166.11].K "sp|Q9NX20|RM16_HUMAN,tr|E9PI14|E9PI14_HUMAN" 2 1142.6931 0.001 64277 12194 3 1142.696185 381.905 "39S ribosomal protein L16, mitochondrial OS=Homo sapiens OX=9606 GN=MRPL16 PE=1 SV=1" 11 2367.3 - 224068 - - - 2.7129 - 2.104 0.464 - 202.6 1 2 0 0.0031 10 0 0 0 0.00E+00 4.05E+06 - - - 5.8846 0.9999 221125_WJC_METTL3_EV_vs_WT_F05.12199.12199.2 2.63E-05 20-Dec R.SLGTADVHFER.K "sp|Q86V81|THOC4_HUMAN,tr|E9PB61|E9PB61_HUMAN" 2 1230.5993 0.67 64280 12199 2 1230.59754 616.3069 THO complex subunit 4 OS=Homo sapiens OX=9606 GN=ALYREF PE=1 SV=3 5.3 2367.8 - 2.54E+06 - - - -1.4302 - 2.354 0.531 - 445.1 1 2 0 -0.0018 11 0 0 0 1.54E+08 2.29E+08 - - - 5.2784 0.9706 221125_WJC_METTL3_EV_vs_WT_F05.12200.12200.3 0.164 Sep-48 K.QIATLHAQVADMK[136.11].K sp|P35579|MYH9_HUMAN 1 1432.7588 1.05 64281 12200 3 1432.757668 478.5935 Myosin-9 OS=Homo sapiens OX=9606 GN=MYH9 PE=1 SV=4 6.74 2367.9 - 1.22E+06 - - - -0.7789 - 1.812 0.116 - 92.4 4 2 0 -0.0011 13 0 0 0 1.01E+07 9.60E+06 - - - 1.166 0.9922 221125_WJC_METTL3_EV_vs_WT_F05.12203.12203.2 0.00964 18-Nov G.SGSGTDFTLK.L "sp|A2NJV5|KV229_HUMAN,sp|A0A087WW87|KV240_HUMAN,sp|P06310|KV230_HUMAN,sp|A0A075B6S2|KVD29_HUMAN,sp|P01614|KVD40_HUMAN,sp|P01615|KVD28_HUMAN,sp|A0A075B6S6|KVD30_HUMAN,sp|A0A075B6P5|KV228_HUMAN,sp|A0A0A0MRZ7|KVD26_HUMAN" 9 1011.4873 999 64284 12203 2 1011.486951 506.7509 Immunoglobulin kappa variable 2-29 OS=Homo sapiens OX=9606 GN=IGKV2-29 PE=3 SV=2 5.55 2368.1 - 999654 - - - -0.3352 - 2.488 0.425 - 516.8 1 1 0 -0.0003 10 0 0 0 2.66E+07 0.00E+00 - - - 4.7242 0.9999 221125_WJC_METTL3_EV_vs_WT_F05.12204.12204.3 0.000525 13/40 K.EVQGISEHYLR.R "sp|Q8IZH2|XRN1_HUMAN,tr|H7C5E4|H7C5E4_HUMAN" 2 1329.6677 1.31 64285 12204 3 1329.66754 444.2298 5'-3' exoribonuclease 1 OS=Homo sapiens OX=9606 GN=XRN1 PE=1 SV=1 5.4 2368.3 - 602103 - - - -0.1309 - 2.258 0.441 - 279.4 1 2 0 -0.0002 11 0 0 0 3.70E+07 2.84E+07 - - - 5.7705 0.9998 221125_WJC_METTL3_EV_vs_WT_F05.12206.12206.2 9.20E-05 20-Sep R.ESVEQQADSFK[136.11].A "sp|O60313|OPA1_HUMAN,tr|A0A2R8YD53|A0A2R8YD53_HUMAN,tr|C9JMB8|C9JMB8_HUMAN,tr|A0A2R8YDM2|A0A2R8YDM2_HUMAN,tr|E5KLJ9|E5KLJ9_HUMAN,tr|A0A2R8Y3X5|A0A2R8Y3X5_HUMAN,tr|A0A2R8YGE5|A0A2R8YGE5_HUMAN,tr|A0A2R8YFD1|A0A2R8YFD1_HUMAN,tr|A0A2R8YE78|A0A2R8YE78_HUMAN" 9 1274.587 1.46 64287 12206 2 1274.588948 638.3008 "Dynamin-like 120 kDa protein, mitochondrial OS=Homo sapiens OX=9606 GN=OPA1 PE=1 SV=3" 4.14 2368.5 - 493327 - - - 1.5197 - 2.134 0.476 - 471.9 1 2 0 0.0019 11 0 0 0 5.53E+06 3.79E+06 - - - 4.6067 0.983 221125_WJC_METTL3_EV_vs_WT_F05.12210.12210.2 0.000113 Oct-36 R.EVGGQGAGNTGGLEPVHPA.S sp|Q7Z5L9|I2BP2_HUMAN 1 1745.8333 - 64291 12210 2 1745.83408 873.9239 Interferon regulatory factor 2-binding protein 2 OS=Homo sapiens OX=9606 GN=IRF2BP2 PE=1 SV=2 4.51 2369 - 259046 - - - 0.4605 - 1.688 0.458 - 60 1 1 0 0.0008 19 0 0 0 - - - - - 3.7107 0.9993 221125_WJC_METTL3_EV_vs_WT_F05.12212.12212.3 0.00438 Nov-36 K.EMEQLVLDK[136.11]K[136.11].Q sp|Q96A49|SYAP1_HUMAN 1 1247.6766 0.86 64292 12212 3 1247.674435 416.8995 Synapse-associated protein 1 OS=Homo sapiens OX=9606 GN=SYAP1 PE=1 SV=1 4.68 2369.2 - 4.96E+06 - - - -1.7545 - 1.777 0.334 - 168.7 1 2 0 -0.0022 10 0 0 0 3.57E+07 4.17E+07 - - - 3.9422 0.9998 221125_WJC_METTL3_EV_vs_WT_F05.12215.12215.3 0.000814 Oct-64 K.IISNASC[160.03]TTNC[160.03]LAPLAK.V "sp|P04406|G3P_HUMAN,tr|E7EUT5|E7EUT5_HUMAN" 2 1832.9125 1.1 64294 12215 3 1832.911977 611.9781 Glyceraldehyde-3-phosphate dehydrogenase OS=Homo sapiens OX=9606 GN=GAPDH PE=1 SV=3 8.06 2369.5 - 1.11E+06 - - - -0.2608 - 1.887 0.413 - 82.9 1 2 0 -0.0005 17 0 0 0 5.28E+07 4.78E+07 - - - 4.7486 0.9969 221125_WJC_METTL3_EV_vs_WT_F05.12216.12216.3 3.51E-05 15/36 S.LGTADVHFER[166.11].K "sp|Q86V81|THOC4_HUMAN,tr|E9PB61|E9PB61_HUMAN" 2 1153.5755 0.73 64295 12216 3 1153.574817 385.5325 THO complex subunit 4 OS=Homo sapiens OX=9606 GN=ALYREF PE=1 SV=3 5.32 2369.6 - 1.01E+06 - - - -0.6285 - 2.624 0.462 - 299.9 1 1 0 -0.0007 10 0 0 0 9.70E+06 1.33E+07 - - - 6.508 0.9824 221125_WJC_METTL3_EV_vs_WT_F05.12217.12217.2 0.00875 14-Dec G.TADVHFER[166.11].K "sp|Q86V81|THOC4_HUMAN,tr|E9PB61|E9PB61_HUMAN" 2 983.47 0.71 64296 12217 2 983.468692 492.7423 THO complex subunit 4 OS=Homo sapiens OX=9606 GN=ALYREF PE=1 SV=3 5.29 2369.8 - 1.01E+06 - - - -1.3442 - 2.098 0.371 - 793 1 1 0 -0.0013 8 0 0 0 1.61E+07 2.25E+07 - - - 4.0156 0.9888 221125_WJC_METTL3_EV_vs_WT_F05.12218.12218.2 5.53E-06 13/18 S.LGTADVHFER[166.11].K "sp|Q86V81|THOC4_HUMAN,tr|E9PB61|E9PB61_HUMAN" 2 1153.5755 0.8 64297 12218 2 1153.577634 577.795 THO complex subunit 4 OS=Homo sapiens OX=9606 GN=ALYREF PE=1 SV=3 5.32 2369.9 - 931511 - - - 1.8135 - 2.59 0.506 - 700.5 1 1 0 0.0021 10 0 0 0 1.72E+07 2.16E+07 - - - 5.434 0.9993 221125_WJC_METTL3_EV_vs_WT_F05.12219.12219.2 0.353 18-Oct K.YEELQVTAGR.H "sp|P48668|K2C6C_HUMAN,sp|O95678|K2C75_HUMAN,sp|P02538|K2C6A_HUMAN" 3 1164.5775 929.58 64298 12219 2 1164.574508 583.296 "Keratin, type II cytoskeletal 6C OS=Homo sapiens OX=9606 GN=KRT6C PE=1 SV=3" 4.53 2370 - 751938 - - - -2.5709 - 2 0.416 - 424.2 1 2 0 -0.003 10 0 0 0 4.80E+07 5.16E+04 - - - 4.0474 0.9932 221125_WJC_METTL3_EV_vs_WT_F05.12220.12220.2 2.31E-05 18-Nov S.LGTADVHFER.K "sp|Q86V81|THOC4_HUMAN,tr|E9PB61|E9PB61_HUMAN" 2 1143.5673 0.8 64299 12220 2 1143.566353 572.7909 THO complex subunit 4 OS=Homo sapiens OX=9606 GN=ALYREF PE=1 SV=3 5.32 2370.1 - 712445 - - - -0.8036 - 2.488 0.485 - 532 1 1 0 -0.0009 10 0 0 0 1.72E+07 2.16E+07 - - - 5.1671 0.9998 221125_WJC_METTL3_EV_vs_WT_F05.12221.12221.2 0.00517 18-Nov K.FADLSEAANR.N "sp|P08670|VIME_HUMAN,tr|B0YJC5|B0YJC5_HUMAN,tr|B0YJC4|B0YJC4_HUMAN" 3 1092.52 2.01 64300 12221 2 1092.519664 547.2673 Vimentin OS=Homo sapiens OX=9606 GN=VIM PE=1 SV=4 4.37 2370.3 - 678900 - - - -0.2956 - 2.005 0.449 - 421.3 1 2 0 -0.0003 10 0 0 0 3.89E+07 1.93E+07 - - - 4.299 0.9844 221125_WJC_METTL3_EV_vs_WT_F05.12223.12223.3 0.0133 Sep-40 K.LKPGDLVGVNK.D "sp|P17980|PRS6A_HUMAN,tr|R4GNH3|R4GNH3_HUMAN,tr|E9PMD8|E9PMD8_HUMAN,tr|E9PKD5|E9PKD5_HUMAN,tr|E9PLG2|E9PLG2_HUMAN,tr|E9PM69|E9PM69_HUMAN" 6 1138.671 0.77 64302 12223 3 1138.668635 380.5643 26S proteasome regulatory subunit 6A OS=Homo sapiens OX=9606 GN=PSMC3 PE=1 SV=3 8.59 2370.5 - 497681 - - - -2.0849 - 1.646 0.177 - 96.5 1 2 0 -0.0024 11 0 0 0 1.52E+07 1.97E+07 - - - 1.9284 0.9998 221125_WJC_METTL3_EV_vs_WT_F05.12224.12224.2 1.01E-05 20-Sep K.DNVDDPTGNFR[166.11].S sp|Q12907|LMAN2_HUMAN 1 1258.5454 1.4 64303 12224 2 1258.543791 630.28 Vesicular integral-membrane protein VIP36 OS=Homo sapiens OX=9606 GN=LMAN2 PE=1 SV=1 3.93 2370.7 - 457407 - - - -1.2499 - 2.016 0.529 - 211.1 1 2 0 -0.0016 11 0 0 0 3.57E+07 2.55E+07 - - - 4.8444 0.9997 221125_WJC_METTL3_EV_vs_WT_F05.12227.12227.2 0.000787 22-Oct K.C[160.03]TSEVIQPNLAK.A "sp|Q5T7M9|DIK1A_HUMAN,tr|A0A087WZK6|A0A087WZK6_HUMAN,tr|A0A087X2C2|A0A087X2C2_HUMAN,tr|A0A087WZ97|A0A087WZ97_HUMAN" 4 1358.6864 6.53 64306 12227 2 1358.686434 680.3505 Divergent protein kinase domain 1A OS=Homo sapiens OX=9606 GN=DIPK1A PE=1 SV=1 5.99 2371.1 - 263480 - - - 0.0243 - 1.885 0.416 - 324.7 1 2 0 0 12 0 0 0 1.36E+07 2.09E+06 - - - 3.7815 0.9999 221125_WJC_METTL3_EV_vs_WT_F05.12230.12230.2 2.48E-05 20-Nov K.DNVDDPTGNFR.S sp|Q12907|LMAN2_HUMAN 1 1248.5371 1.4 64307 12230 2 1248.535641 625.2758 Vesicular integral-membrane protein VIP36 OS=Homo sapiens OX=9606 GN=LMAN2 PE=1 SV=1 3.93 2371.5 - 1.45E+06 - - - -1.1638 - 2.448 0.529 - 420 1 2 0 -0.0015 11 0 0 0 3.57E+07 2.54E+07 - - - 5.3697 1 221125_WJC_METTL3_EV_vs_WT_F05.12233.12233.2 1.47E-07 16/22 R.HVDYVADQIVTK[136.11].L sp|P11388|TOP2A_HUMAN 1 1394.7285 0.26 64310 12233 2 1394.724482 698.3715 DNA topoisomerase 2-alpha OS=Homo sapiens OX=9606 GN=TOP2A PE=1 SV=3 5.21 2371.9 - 320060 - - - -2.9024 - 3.084 0.579 - 465.7 1 2 0 -0.004 12 0 0 0 1.22E+06 4.75E+06 - - - 6.2795 1 221125_WJC_METTL3_EV_vs_WT_F05.12236.12236.3 4.96E-07 13/48 K.VVSQYHELVVQAR.D "sp|Q16891|MIC60_HUMAN,tr|B9A067|B9A067_HUMAN,tr|C9J406|C9J406_HUMAN,tr|H7C463|H7C463_HUMAN" 4 1526.8205 1.27 64311 12236 3 1526.820974 509.9475 MICOS complex subunit MIC60 OS=Homo sapiens OX=9606 GN=IMMT PE=1 SV=1 6.72 2372.2 - 2.32E+06 - - - 0.2934 - 2.594 0.584 - 255.3 1 2 0 0.0004 13 0 0 0 8.51E+07 6.72E+07 - - - 7.6353 1 221125_WJC_METTL3_EV_vs_WT_F05.12237.12237.2 9.74E-05 14/28 R.LGNAGDVC[160.03]VPQASPR[166.11].R sp|Q9H0W5|CCDC8_HUMAN 1 1549.7546 1.19 64312 12237 2 1549.753963 775.8846 Coiled-coil domain-containing protein 8 OS=Homo sapiens OX=9606 GN=CCDC8 PE=1 SV=2 5.83 2372.4 - 924325 - - - -0.4401 - 3.054 0.637 - 537.3 1 2 0 -0.0007 15 0 0 0 2.33E+07 1.96E+07 - - - 6.4905 0.9998 221125_WJC_METTL3_EV_vs_WT_F05.12238.12238.2 0.0058 18-Oct K.KLEIGFNGNR.L "sp|Q9HD45|TM9S3_HUMAN,tr|Q5TB53|Q5TB53_HUMAN" 2 1146.6146 1.42 64313 12238 2 1146.614767 574.3146 Transmembrane 9 superfamily member 3 OS=Homo sapiens OX=9606 GN=TM9SF3 PE=1 SV=2 8.75 2372.5 - 1.21E+06 - - - 0.184 - 2.341 0.407 - 360.8 1 2 0 0.0002 10 0 0 0 2.48E+07 1.74E+07 - - - 4.4213 1 221125_WJC_METTL3_EV_vs_WT_F05.12240.12240.3 1.80E-05 13/44 R.HVDYVADQIVTK[136.11].L sp|P11388|TOP2A_HUMAN 1 1394.7285 1.18 64315 12240 3 1394.726503 465.9168 DNA topoisomerase 2-alpha OS=Homo sapiens OX=9606 GN=TOP2A PE=1 SV=3 5.21 2372.7 - 912665 - - - -1.4533 - 2.45 0.512 - 367 1 2 0 -0.002 12 0 0 0 2.35E+07 1.98E+07 - - - 6.7316 0.9999 221125_WJC_METTL3_EV_vs_WT_F05.12244.12244.3 1.68E-05 Nov-44 R.HVDYVADQIVTK.L sp|P11388|TOP2A_HUMAN 1 1386.7143 1.04 64317 12244 3 1386.713139 463.2454 DNA topoisomerase 2-alpha OS=Homo sapiens OX=9606 GN=TOP2A PE=1 SV=3 5.21 2373.2 - 1.34E+06 - - - -0.8589 - 2.237 0.448 - 269.8 1 2 0 -0.0012 12 0 0 0 2.39E+07 2.28E+07 - - - 5.7661 0.9198 221125_WJC_METTL3_EV_vs_WT_F05.12246.12246.2 4.6 22-Jul R.R[166.11]LEESDVLQEAR[166.11].R "sp|O43615|TIM44_HUMAN,tr|M0R301|M0R301_HUMAN,tr|M0R124|M0R124_HUMAN,tr|M0QXU7|M0QXU7_HUMAN" 4 1463.7483 0.52 64319 12246 2 1463.751248 732.8814 Mitochondrial import inner membrane translocase subunit TIM44 OS=Homo sapiens OX=9606 GN=TIMM44 PE=1 SV=2 4.41 2373.5 - 305745 - - - 2.0065 - 1.165 0.045 - 50.4 1 2 0 0.0029 12 0 0 0 5.85E+06 1.12E+07 - - - -0.2257 1 221125_WJC_METTL3_EV_vs_WT_F05.12247.12247.2 8.80E-10 14/24 K.VVSQYHELVVQAR.D "sp|Q16891|MIC60_HUMAN,tr|B9A067|B9A067_HUMAN,tr|C9J406|C9J406_HUMAN,tr|H7C463|H7C463_HUMAN" 4 1526.8205 1.23 64320 12247 2 1526.82012 764.4175 MICOS complex subunit MIC60 OS=Homo sapiens OX=9606 GN=IMMT PE=1 SV=1 6.72 2373.6 - 186010 - - - -0.2659 - 2.823 0.681 - 839.2 1 2 0 -0.0004 13 0 0 0 3.89E+06 3.16E+06 - - - 6.7343 0.9791 221125_WJC_METTL3_EV_vs_WT_F05.12249.12249.3 0.364 Sep-36 K.ESSTVFELK[136.11]R[166.11].L "sp|Q15370|ELOB_HUMAN,tr|I3L0M9|I3L0M9_HUMAN,tr|A0A0B4J296|A0A0B4J296_HUMAN,tr|B8ZZU8|B8ZZU8_HUMAN" 4 1212.6469 0.94 64321 12249 3 1212.646649 405.2229 Elongin-B OS=Homo sapiens OX=9606 GN=ELOB PE=1 SV=1 6.24 2373.9 - 997907 - - - -0.2251 - 1.397 0.166 - 126.6 1 2 0 -0.0003 10 0 0 0 3.43E+07 3.65E+07 - - - 1.367 0.9775 221125_WJC_METTL3_EV_vs_WT_F05.12254.12254.3 0.0854 Oct-40 K.LK[136.11]PGDLVGVNK[136.11].D "sp|P17980|PRS6A_HUMAN,tr|R4GNH3|R4GNH3_HUMAN,tr|E9PMD8|E9PMD8_HUMAN,tr|E9PKD5|E9PKD5_HUMAN,tr|E9PLG2|E9PLG2_HUMAN,tr|E9PM69|E9PM69_HUMAN" 6 1154.6994 0.77 64325 12254 3 1154.6976 385.9071 26S proteasome regulatory subunit 6A OS=Homo sapiens OX=9606 GN=PSMC3 PE=1 SV=3 8.59 2374.4 - 807926 - - - -1.5666 - 1.252 0.208 - 82.2 1 2 0 -0.0018 11 0 0 0 1.51E+07 1.98E+07 - - - 1.4969 0.9995 221125_WJC_METTL3_EV_vs_WT_F05.12256.12256.2 8.06E-09 20-Nov K.GC[160.03]ENLNIVQDK.L sp|Q7Z417|NUFP2_HUMAN 1 1288.6082 1.75 64327 12256 2 1288.60428 645.3114 Nuclear fragile X mental retardation-interacting protein 2 OS=Homo sapiens OX=9606 GN=NUFIP2 PE=1 SV=1 4.37 2374.5 - 442629 - - - -3.004 - 2.383 0.482 - 662.7 1 2 0 -0.0039 11 0 0 0 1.53E+07 8.76E+06 - - - 4.949 1 221125_WJC_METTL3_EV_vs_WT_F05.12261.12261.3 1.40E-08 14/48 K.VVSQYHELVVQAR[166.11].D "sp|Q16891|MIC60_HUMAN,tr|B9A067|B9A067_HUMAN,tr|C9J406|C9J406_HUMAN,tr|H7C463|H7C463_HUMAN" 4 1536.8288 1.27 64330 12261 3 1536.828409 513.2835 MICOS complex subunit MIC60 OS=Homo sapiens OX=9606 GN=IMMT PE=1 SV=1 6.72 2375.2 - 5.37E+06 - - - -0.2518 - 2.678 0.594 - 333.4 1 2 0 -0.0004 13 0 0 0 8.51E+07 6.72E+07 - - - 7.8332 0.9999 221125_WJC_METTL3_EV_vs_WT_F05.12262.12262.3 0.00308 13/44 R.RLEESDVLQEAR.R "sp|O43615|TIM44_HUMAN,tr|M0R301|M0R301_HUMAN,tr|M0R124|M0R124_HUMAN,tr|M0QXU7|M0QXU7_HUMAN" 4 1443.7318 1.23 64331 12262 3 1443.730717 482.2512 Mitochondrial import inner membrane translocase subunit TIM44 OS=Homo sapiens OX=9606 GN=TIMM44 PE=1 SV=2 4.41 2375.3 - 4.07E+06 - - - -0.7301 - 2.731 0.383 - 270.4 1 2 0 -0.0011 12 0 0 0 9.75E+07 7.90E+07 - - - 5.5946 1 221125_WJC_METTL3_EV_vs_WT_F05.12265.12265.2 1.68E-06 13/20 M.SHTILLVQPTK.R "sp|P84090|ERH_HUMAN,tr|G3V279|G3V279_HUMAN" 2 1235.7238 2.8 64334 12265 2 1235.723022 618.8692 Enhancer of rudimentary homolog OS=Homo sapiens OX=9606 GN=ERH PE=1 SV=1 8.49 2375.6 - 661479 - - - -0.6069 - 2.919 0.577 - 534.4 1 2 0 -0.0008 11 0 0 0 1.51E+07 5.39E+06 - - - 6.2004 0.9999 221125_WJC_METTL3_EV_vs_WT_F05.12267.12267.2 0.00027 17/22 R.RLEESDVLQEAR.R "sp|O43615|TIM44_HUMAN,tr|M0R301|M0R301_HUMAN,tr|M0R124|M0R124_HUMAN,tr|M0QXU7|M0QXU7_HUMAN" 4 1443.7318 0.52 64336 12267 2 1443.731785 722.8732 Mitochondrial import inner membrane translocase subunit TIM44 OS=Homo sapiens OX=9606 GN=TIMM44 PE=1 SV=2 4.41 2375.9 - 664906 - - - 0.0097 - 2.693 0.464 - 471.8 1 2 0 0 12 0 0 0 5.85E+06 1.12E+07 - - - 5.0747 0.9776 221125_WJC_METTL3_EV_vs_WT_F05.12269.12269.2 0.187 22-Jun K.VIGQDSSEIHFK[136.11].V "sp|P63165|SUMO1_HUMAN,sp|G2XKQ0|SUMO5_HUMAN,tr|B8ZZJ0|B8ZZJ0_HUMAN,tr|B8ZZN6|B8ZZN6_HUMAN,tr|B9A032|B9A032_HUMAN" 5 1366.6972 4.98 64338 12269 2 1366.692704 684.3559 Small ubiquitin-related modifier 1 OS=Homo sapiens OX=9606 GN=SUMO1 PE=1 SV=1 5.32 2376.1 - 225195 - - - -3.3116 - 1.167 0.245 - 55 1 2 0 -0.0045 12 0 0 0 1.21E+07 2.44E+06 - - - 1.2555 0.9998 221125_WJC_METTL3_EV_vs_WT_F05.12272.12272.3 9.14E-05 Aug-44 K.VIGQDSSEIHFK.V "sp|P63165|SUMO1_HUMAN,sp|G2XKQ0|SUMO5_HUMAN,tr|B8ZZJ0|B8ZZJ0_HUMAN,tr|B8ZZN6|B8ZZN6_HUMAN,tr|B9A032|B9A032_HUMAN" 5 1358.683 0.67 64339 12272 3 1358.683326 453.9016 Small ubiquitin-related modifier 1 OS=Homo sapiens OX=9606 GN=SUMO1 PE=1 SV=1 5.32 2376.6 - 1.13E+06 - - - 0.2179 - 2.009 0.354 - 77.4 1 2 0 0.0003 12 0 0 0 1.76E+07 2.62E+07 - - - 4.4204 1 221125_WJC_METTL3_EV_vs_WT_F05.12273.12273.3 0.00191 18/56 R.LPEYTLSQEGGPAHK.R "sp|O75569|PRKRA_HUMAN,tr|B4DJC7|B4DJC7_HUMAN,tr|A0A7I2V3J2|A0A7I2V3J2_HUMAN,tr|A0A7I2V2I8|A0A7I2V2I8_HUMAN,tr|A0A7I2V5H3|A0A7I2V5H3_HUMAN,tr|A0A7I2YQ87|A0A7I2YQ87_HUMAN" 6 1625.8049 1.6 64340 12273 3 1625.807055 542.9423 Interferon-inducible double-stranded RNA-dependent protein kinase activator A OS=Homo sapiens OX=9606 GN=PRKRA PE=1 SV=1 5.4 2376.7 - 1.01E+06 - - - 1.3034 - 2.716 0.455 - 362.2 1 2 0 0.0021 15 0 0 0 1.41E+07 8.85E+06 - - - 6.2194 0.9788 221125_WJC_METTL3_EV_vs_WT_F05.12275.12275.3 0.0908 15/48 R.QTIQYIHPADAVK[136.11].L "sp|Q9H0A0|NAT10_HUMAN,tr|A0A087WV29|A0A087WV29_HUMAN" 2 1490.7973 0.72 64342 12275 3 1490.797654 497.9397 RNA cytidine acetyltransferase OS=Homo sapiens OX=9606 GN=NAT10 PE=1 SV=2 6.74 2376.9 - 483471 - - - 0.2522 - 2.263 0.054 - 286.6 1 2 0 0.0004 13 0 0 0 1.15E+07 1.60E+07 - - - 1.3562 0.9952 221125_WJC_METTL3_EV_vs_WT_F05.12276.12276.3 0.0307 Nov-52 K.TLSVSPSVERPDYR.N "sp|Q99707|METH_HUMAN,tr|A0A7P0T9G7|A0A7P0T9G7_HUMAN,tr|A0A7P0TAJ0|A0A7P0TAJ0_HUMAN,tr|A0A6Q8PGK3|A0A6Q8PGK3_HUMAN,tr|A0A7P0TAV2|A0A7P0TAV2_HUMAN,tr|A0A494C064|A0A494C064_HUMAN,tr|A0A494C1A2|A0A494C1A2_HUMAN,tr|A0A7P0TA06|A0A7P0TA06_HUMAN" 8 1604.8158 3.03 64343 12276 3 1604.818235 535.9459 Methionine synthase OS=Homo sapiens OX=9606 GN=MTR PE=1 SV=2 5.74 2377 - 402304 - - - 1.4955 - 1.497 0.258 - 117.7 1 2 0 0.0024 14 0 0 0 9.01E+06 2.97E+06 - - - 2.488 0.9988 221125_WJC_METTL3_EV_vs_WT_F05.12280.12280.2 1.35E-05 30-Sep R.LNNAPVAGYEGDVGSK[136.11].T "sp|Q11206|SIA4C_HUMAN,tr|A0A7P0RGI5|A0A7P0RGI5_HUMAN,tr|E9PQZ2|E9PQZ2_HUMAN,tr|A0A7I2V4F4|A0A7I2V4F4_HUMAN,tr|A0A7I2V4V4|A0A7I2V4V4_HUMAN,tr|A0A7I2V4R4|A0A7I2V4R4_HUMAN,tr|A0A7I2V5F3|A0A7I2V5F3_HUMAN" 7 1597.7828 2.42 64347 12280 2 1597.776789 799.8987 "CMP-N-acetylneuraminate-beta-galactosamide-alpha-2,3-sialyltransferase 4 OS=Homo sapiens OX=9606 GN=ST3GAL4 PE=1 SV=1" 4.37 2377.6 - 175351 - - - -3.7308 - 2.05 0.484 - 209.5 1 2 0 -0.006 16 0 0 0 3.04E+06 1.26E+06 - - - 4.3788 0.9526 221125_WJC_METTL3_EV_vs_WT_F05.12281.12281.2 0.00041 Jul-32 K.IETAVTSTPSASGQFSK.P "sp|P35658|NU214_HUMAN,tr|A0A0A0MSW3|A0A0A0MSW3_HUMAN,tr|B7ZAV2|B7ZAV2_HUMAN,tr|A0A494C1F2|A0A494C1F2_HUMAN,tr|A0A494C104|A0A494C104_HUMAN,tr|H0Y837|H0Y837_HUMAN" 6 1709.8472 999 64348 12281 2 1709.842797 855.9309 Nuclear pore complex protein Nup214 OS=Homo sapiens OX=9606 GN=NUP214 PE=1 SV=2 6 2377.7 - 121111 - - - -2.5722 - 1.678 0.469 - 84.4 1 1 0 -0.0044 17 0 0 0 1.41E+06 0.00E+00 - - - 3.7762 1 221125_WJC_METTL3_EV_vs_WT_F05.12287.12287.2 2.37E-08 14/24 K.ASLEGNLAETENR.Y "sp|Q04695|K1C17_HUMAN,tr|F5GWP8|F5GWP8_HUMAN" 2 1402.6688 312.74 64352 12287 2 1402.669065 702.3417 "Keratin, type I cytoskeletal 17 OS=Homo sapiens OX=9606 GN=KRT17 PE=1 SV=2" 4.25 2378.4 - 847414 - - - 0.1633 - 2.908 0.585 - 656.1 1 2 0 0.0002 13 0 0 0 2.80E+08 8.96E+05 - - - 6.1014 0.9995 221125_WJC_METTL3_EV_vs_WT_F05.12288.12288.3 0.000668 15/48 R.QTIQYIHPADAVK.L "sp|Q9H0A0|NAT10_HUMAN,tr|A0A087WV29|A0A087WV29_HUMAN" 2 1482.7831 0.75 64353 12288 3 1482.784207 495.2683 RNA cytidine acetyltransferase OS=Homo sapiens OX=9606 GN=NAT10 PE=1 SV=2 6.74 2378.5 - 767636 - - - 0.7614 - 2.245 0.274 - 288 1 2 0 0.0011 13 0 0 0 1.16E+07 1.54E+07 - - - 3.7872 0.9999 221125_WJC_METTL3_EV_vs_WT_F05.12290.12290.3 0.00809 13/40 K.TQIDHYVGIAR.D sp|O95197|RTN3_HUMAN 1 1271.6622 0.89 64355 12290 3 1271.661242 424.8947 Reticulon-3 OS=Homo sapiens OX=9606 GN=RTN3 PE=1 SV=2 6.41 2378.7 - 556211 - - - -0.7809 - 2.502 0.386 - 342 1 2 0 -0.001 11 0 0 0 2.61E+07 2.95E+07 - - - 5.4485 0.9999 221125_WJC_METTL3_EV_vs_WT_F05.12291.12291.2 0.000166 18-Oct R.AEAESWYQTK.Y "sp|P48668|K2C6C_HUMAN,sp|P04259|K2C6B_HUMAN,sp|O95678|K2C75_HUMAN,sp|P02538|K2C6A_HUMAN" 4 1211.5459 2.47 64356 12291 2 1211.546259 606.7802 "Keratin, type II cytoskeletal 6C OS=Homo sapiens OX=9606 GN=KRT6C PE=1 SV=3" 4.53 2378.8 - 481151 - - - 0.3227 - 2.233 0.507 - 410.6 1 2 0 0.0004 10 0 0 0 3.40E+07 1.38E+07 - - - 5.028 0.9998 221125_WJC_METTL3_EV_vs_WT_F05.12292.12292.2 9.54E-07 13/24 R.ALGQNPTNAEVLK.V "sp|P14649|MYL6B_HUMAN,sp|P60660|MYL6_HUMAN,tr|F8W1R7|F8W1R7_HUMAN,tr|G3V1V0|G3V1V0_HUMAN,tr|B7Z6Z4|B7Z6Z4_HUMAN,tr|G8JLA2|G8JLA2_HUMAN,tr|F8W1I5|F8W1I5_HUMAN,tr|J3KND3|J3KND3_HUMAN,tr|F8VPF3|F8VPF3_HUMAN" 9 1353.7252 1.66 64357 12292 2 1353.727871 677.8699 Myosin light chain 6B OS=Homo sapiens OX=9606 GN=MYL6B PE=1 SV=1 6.05 2379 - 410009 - - - 1.9517 - 2.742 0.543 - 538.5 1 2 0 0.0026 13 0 0 0 5.00E+06 3.02E+06 - - - 5.6396 0.997 221125_WJC_METTL3_EV_vs_WT_F05.12293.12293.2 0.0628 20-Jun K.LK[136.11]PGDLVGVNK[136.11].D "sp|P17980|PRS6A_HUMAN,tr|R4GNH3|R4GNH3_HUMAN,tr|E9PMD8|E9PMD8_HUMAN,tr|E9PKD5|E9PKD5_HUMAN,tr|E9PLG2|E9PLG2_HUMAN,tr|E9PM69|E9PM69_HUMAN" 6 1154.6994 0.74 64358 12293 2 1154.700796 578.357 26S proteasome regulatory subunit 6A OS=Homo sapiens OX=9606 GN=PSMC3 PE=1 SV=3 8.59 2379.1 - 349337 - - - 1.2012 - 1.144 0.321 - 57.7 1 2 0 0.0014 11 0 0 0 4.11E+06 5.57E+06 - - - 1.7754 0.9999 221125_WJC_METTL3_EV_vs_WT_F05.12296.12296.3 5.00E-06 15/48 K.QGEVIVSIEEK[136.11]PK[136.11].E "sp|P49321|NASP_HUMAN,tr|E9PPR5|E9PPR5_HUMAN" 2 1470.8265 0.87 64361 12296 3 1470.825965 491.2828 Nuclear autoantigenic sperm protein OS=Homo sapiens OX=9606 GN=NASP PE=1 SV=2 4.79 2379.5 - 269598 - - - -0.3365 - 2.454 0.432 - 382.7 1 2 0 -0.0005 13 0 0 0 4.81E+06 5.53E+06 - - - 5.7902 0.9998 221125_WJC_METTL3_EV_vs_WT_F05.12298.12298.2 3.52E-07 26-Nov K.TSSLDPNDQVAMGR.Q "sp|Q9NY61|AATF_HUMAN,tr|A0A7P0T868|A0A7P0T868_HUMAN,tr|A0A0J9YWE9|A0A0J9YWE9_HUMAN,tr|A0A7P0TAR0|A0A7P0TAR0_HUMAN,tr|A0A087WWS8|A0A087WWS8_HUMAN,tr|A0A7P0TBI0|A0A7P0TBI0_HUMAN,tr|A0A7P0Z4P2|A0A7P0Z4P2_HUMAN,tr|A0A087WTH8|A0A087WTH8_HUMAN" 8 1489.6831 1.05 64363 12298 2 1489.68621 745.8488 Protein AATF OS=Homo sapiens OX=9606 GN=AATF PE=1 SV=1 4.21 2379.7 - 137978 - - - 2.0837 - 2.283 0.602 - 277.2 1 2 0 0.0031 14 0 0 0 2.79E+06 2.66E+06 - - - 5.5579 0.9999 221125_WJC_METTL3_EV_vs_WT_F05.12300.12300.3 0.00069 Dec-36 K.KLEIGFNGNR.L "sp|Q9HD45|TM9S3_HUMAN,tr|Q5TB53|Q5TB53_HUMAN" 2 1146.6146 1.36 64364 12300 3 1146.614863 383.2121 Transmembrane 9 superfamily member 3 OS=Homo sapiens OX=9606 GN=TM9SF3 PE=1 SV=2 8.75 2380 - 1.65E+06 - - - 0.2677 - 2.095 0.46 - 178.8 1 2 0 0.0003 10 0 0 0 6.74E+07 4.96E+07 - - - 5.8283 0.9979 221125_WJC_METTL3_EV_vs_WT_F05.12302.12302.3 0.00199 Dec-36 K.LQEIEEFKER.L "sp|P0DJ07|PT100_HUMAN,tr|A0A0A0MSK2|A0A0A0MSK2_HUMAN" 2 1319.6721 0.7 64365 12302 3 1319.672273 440.898 "Protein PET100 homolog, mitochondrial OS=Homo sapiens OX=9606 GN=PET100 PE=1 SV=1" 4.49 2380.2 - 2.76E+06 - - - 0.1076 - 2.529 0.236 - 400 1 2 1 0.0001 10 0 0 0 2.95E+07 4.24E+07 - - - 3.8808 0.9999 221125_WJC_METTL3_EV_vs_WT_F05.12303.12303.3 6.15E-07 13/40 K.TQIDHYVGIAR[166.11].D sp|O95197|RTN3_HUMAN 1 1281.6705 0.9 64366 12303 3 1281.67232 428.2308 Reticulon-3 OS=Homo sapiens OX=9606 GN=RTN3 PE=1 SV=2 6.41 2380.2 - 2.00E+06 - - - 1.4161 - 2.252 0.473 - 319.4 1 2 0 0.0018 11 0 0 0 2.61E+07 2.92E+07 - - - 6.1192 0.9994 221125_WJC_METTL3_EV_vs_WT_F05.12304.12304.2 0.0247 18-Nov R.RLSESQLSFR.R sp|Q96PK6|RBM14_HUMAN 1 1221.6466 1.84 64367 12304 2 1221.647606 611.8306 RNA-binding protein 14 OS=Homo sapiens OX=9606 GN=RBM14 PE=1 SV=2 9.6 2380.3 - 1.98E+06 - - - 0.8358 - 1.776 0.332 - 169.9 1 2 0 0.001 10 0 0 0 1.97E+07 1.07E+07 - - - 3.0961 0.9998 221125_WJC_METTL3_EV_vs_WT_F05.12305.12305.2 0.000111 18-Nov R.R[166.11]LSESQLSFR[166.11].R sp|Q96PK6|RBM14_HUMAN 1 1241.6631 1.86 64368 12305 2 1241.664625 621.8388 RNA-binding protein 14 OS=Homo sapiens OX=9606 GN=RBM14 PE=1 SV=2 9.6 2380.4 - 1.09E+06 - - - 1.2081 - 2.32 0.397 - 171.5 1 2 0 0.0015 10 0 0 0 1.97E+07 1.06E+07 - - - 4.3218 0.9999 221125_WJC_METTL3_EV_vs_WT_F05.12306.12306.3 4.42E-05 Oct-48 K.ASLEGNLAETENR.Y "sp|Q04695|K1C17_HUMAN,tr|F5GWP8|F5GWP8_HUMAN" 2 1402.6688 35.74 64369 12306 3 1402.669906 468.5636 "Keratin, type I cytoskeletal 17 OS=Homo sapiens OX=9606 GN=KRT17 PE=1 SV=2" 4.25 2380.5 - 725817 - - - 0.7628 - 2.076 0.436 - 159.5 1 2 0 0.0011 13 0 0 0 3.88E+07 1.09E+06 - - - 5.3811 1 221125_WJC_METTL3_EV_vs_WT_F05.12307.12307.3 1.05E-05 Dec-52 K.LGHYATQLQNTYDR[166.11].C "sp|P51692|STA5B_HUMAN,tr|C9J4I3|C9J4I3_HUMAN" 2 1688.8146 0.24 64370 12307 3 1688.815905 563.9455 Signal transducer and activator of transcription 5B OS=Homo sapiens OX=9606 GN=STAT5B PE=1 SV=2 6.74 2380.6 - 582891 - - - 0.771 - 2.716 0.475 - 236 1 2 0 0.0013 14 0 0 0 1.67E+06 6.85E+06 - - - 6.4907 1 221125_WJC_METTL3_EV_vs_WT_F05.12309.12309.3 4.29E-06 17/52 K.VGQEIEVRPGIVSK.D sp|P41091|IF2G_HUMAN 1 1509.8515 0.97 64372 12309 3 1509.851386 504.2911 Eukaryotic translation initiation factor 2 subunit 3 OS=Homo sapiens OX=9606 GN=EIF2S3 PE=1 SV=3 6.11 2380.8 - 379139 - - - -0.0702 - 2.97 0.506 - 427 1 2 0 -0.0001 14 0 0 0 1.08E+08 1.11E+08 - - - 7.0743 0.916 221125_WJC_METTL3_EV_vs_WT_F05.12311.12311.3 0.00151 Sep-40 F.AHLDATTVLSR.A "sp|P06576|ATPB_HUMAN,tr|H0YI37|H0YI37_HUMAN,tr|H0YH81|H0YH81_HUMAN" 3 1182.6357 1.46 64374 12311 3 1182.638314 395.2192 "ATP synthase subunit beta, mitochondrial OS=Homo sapiens OX=9606 GN=ATP5F1B PE=1 SV=3" 6.79 2381.1 - 271682 - - - 2.2222 - 1.855 0.334 - 168.9 1 1 0 0.0026 11 0 0 0 2.48E+06 1.70E+06 - - - 4.0183 0.9291 221125_WJC_METTL3_EV_vs_WT_F05.12312.12312.2 0.226 18-Sep K.LQEIEEFKER.L "sp|P0DJ07|PT100_HUMAN,tr|A0A0A0MSK2|A0A0A0MSK2_HUMAN" 2 1319.6721 0.82 64375 12312 2 1319.674293 660.8433 "Protein PET100 homolog, mitochondrial OS=Homo sapiens OX=9606 GN=PET100 PE=1 SV=1" 4.49 2381.2 - 297422 - - - 1.6383 - 1.577 0.138 - 161.9 1 2 1 0.0022 10 0 0 0 2.24E+06 2.73E+06 - - - 1.3311 0.9995 221125_WJC_METTL3_EV_vs_WT_F05.12316.12316.3 0.00692 Oct-52 K.FLETESHPSIPPPK.L "sp|Q15643|TRIPB_HUMAN,tr|H0YJ97|H0YJ97_HUMAN" 2 1577.809 1.47 64378 12316 3 1577.808964 526.9436 Thyroid receptor-interacting protein 11 OS=Homo sapiens OX=9606 GN=TRIP11 PE=1 SV=3 5.4 2381.7 - 598561 - - - 0.0032 - 1.573 0.373 - 73 1 2 0 0 14 0 0 0 2.82E+07 1.92E+07 - - - 3.9024 1 221125_WJC_METTL3_EV_vs_WT_F05.12318.12318.3 7.60E-05 Nov-40 M.SHTILLVQPTK.R "sp|P84090|ERH_HUMAN,tr|G3V279|G3V279_HUMAN" 2 1235.7238 2.16 64380 12318 3 1235.724707 412.9152 Enhancer of rudimentary homolog OS=Homo sapiens OX=9606 GN=ERH PE=1 SV=1 8.49 2381.9 - 4.33E+06 - - - 0.7566 - 2.376 0.461 - 202.9 1 2 0 0.0009 11 0 0 0 7.74E+07 3.59E+07 - - - 6.1379 0.8957 221125_WJC_METTL3_EV_vs_WT_F05.12319.12319.3 1.14 Sep-40 M.SHTILLVQPTK[136.11].R "sp|P84090|ERH_HUMAN,tr|G3V279|G3V279_HUMAN" 2 1243.738 2.16 64381 12319 3 1243.738046 415.5866 Enhancer of rudimentary homolog OS=Homo sapiens OX=9606 GN=ERH PE=1 SV=1 8.49 2381.9 - 3.37E+06 - - - 0.0595 - 1.279 0.106 - 105.3 1 2 0 0.0001 11 0 0 0 7.73E+07 3.58E+07 - - - 0.4208 0.9999 221125_WJC_METTL3_EV_vs_WT_F05.12321.12321.3 0.00337 13/56 R.LVVHEGSPVTSISAR.S "sp|Q9H1Z4|WDR13_HUMAN,tr|A0A087X091|A0A087X091_HUMAN" 2 1550.8417 1.59 64383 12321 3 1550.842489 517.9545 WD repeat-containing protein 13 OS=Homo sapiens OX=9606 GN=WDR13 PE=1 SV=2 6.75 2382.2 - 573817 - - - 0.5371 - 2.17 0.392 - 260.7 1 2 0 0.0008 15 0 0 0 6.66E+06 4.19E+06 - - - 4.9317 0.9993 221125_WJC_METTL3_EV_vs_WT_F05.12322.12322.3 0.00114 Nov-36 K.FALKEEDISR.K "sp|Q9H019|MFR1L_HUMAN,tr|E9PLD2|E9PLD2_HUMAN" 2 1206.6245 1.07 64384 12322 3 1206.624552 403.2154 Mitochondrial fission regulator 1-like OS=Homo sapiens OX=9606 GN=MTFR1L PE=1 SV=2 4.68 2382.3 - 549993 - - - 0.0829 - 2.199 0.354 - 127.6 1 2 1 0.0001 10 0 0 0 1.11E+07 1.04E+07 - - - 4.788 0.9998 221125_WJC_METTL3_EV_vs_WT_F05.12323.12323.3 2.81E-05 13/56 R.LVVHEGSPVTSISAR[166.11].S "sp|Q9H1Z4|WDR13_HUMAN,tr|A0A087X091|A0A087X091_HUMAN" 2 1560.8499 1.55 64385 12323 3 1560.848126 521.2906 WD repeat-containing protein 13 OS=Homo sapiens OX=9606 GN=WDR13 PE=1 SV=2 6.75 2382.4 - 397011 - - - -1.1532 - 2.242 0.346 - 97.3 1 2 0 -0.0018 15 0 0 0 6.73E+06 4.34E+06 - - - 4.5038 0.984 221125_WJC_METTL3_EV_vs_WT_F05.12324.12324.2 0.354 18-Sep K.LQEIEEFK[136.11]ER[166.11].L "sp|P0DJ07|PT100_HUMAN,tr|A0A0A0MSK2|A0A0A0MSK2_HUMAN" 2 1337.6946 0.8 64386 12324 2 1337.695991 669.8546 "Protein PET100 homolog, mitochondrial OS=Homo sapiens OX=9606 GN=PET100 PE=1 SV=1" 4.49 2382.6 - 199123 - - - 1.0391 - 1.805 0.219 - 302.5 1 2 1 0.0014 10 0 0 0 2.19E+06 2.73E+06 - - - 2.3065 0.9993 221125_WJC_METTL3_EV_vs_WT_F05.12325.12325.2 0.0426 22-Aug K.TESDFSNLDSEK[136.11].H "sp|Q9H825|METL8_HUMAN,tr|E7ETE0|E7ETE0_HUMAN,tr|B5ME25|B5ME25_HUMAN,tr|B3KW44|B3KW44_HUMAN" 4 1378.598 0.97 64387 12325 2 1378.598275 690.3063 mRNA N(3)-methylcytidine methyltransferase METTL8 OS=Homo sapiens OX=9606 GN=METTL8 PE=1 SV=2 3.92 2382.7 - 159086 - - - 0.222 - 1.413 0.372 - 110.2 1 2 0 0.0003 12 0 0 0 8.73E+05 8.98E+05 - - - 2.6981 1 221125_WJC_METTL3_EV_vs_WT_F05.12331.12331.3 1.34E-06 17/52 K.VGQEIEVR[166.11]PGIVSK[136.11].D sp|P41091|IF2G_HUMAN 1 1527.874 0.97 64391 12331 3 1527.876138 510.2986 Eukaryotic translation initiation factor 2 subunit 3 OS=Homo sapiens OX=9606 GN=EIF2S3 PE=1 SV=3 6.11 2383.5 - 5.97E+06 - - - 1.4242 - 3.523 0.557 - 537 1 2 0 0.0022 14 0 0 0 1.08E+08 1.11E+08 - - - 8.0961 0.9873 221125_WJC_METTL3_EV_vs_WT_F05.12333.12333.2 0.00238 20-Jul K.TQIDHYVGIAR[166.11].D sp|O95197|RTN3_HUMAN 1 1281.6705 0.77 64393 12333 2 1281.675366 641.8425 Reticulon-3 OS=Homo sapiens OX=9606 GN=RTN3 PE=1 SV=2 6.41 2383.8 - 403841 - - - 3.7927 - 1.627 0.239 - 146.1 2 2 0 0.0049 11 0 0 0 1.69E+06 2.19E+06 - - - 1.987 0.9991 221125_WJC_METTL3_EV_vs_WT_F05.12336.12336.2 0.000135 24-Oct K.EPINSTTPFNSSK.L sp|Q8WYP5|ELYS_HUMAN 1 1420.6834 0.8 64396 12336 2 1420.679141 711.349 Protein ELYS OS=Homo sapiens OX=9606 GN=AHCTF1 PE=1 SV=3 6.1 2384.1 - 263674 - - - -3.0147 - 1.995 0.44 - 271.9 1 2 0 -0.0043 13 0 0 0 2.78E+06 3.47E+06 - - - 4.0621 1 221125_WJC_METTL3_EV_vs_WT_F05.12340.12340.2 1.50E-07 13/26 K.VGQEIEVR[166.11]PGIVSK[136.11].D sp|P41091|IF2G_HUMAN 1 1527.874 0.98 64400 12340 2 1527.879784 764.9443 Eukaryotic translation initiation factor 2 subunit 3 OS=Homo sapiens OX=9606 GN=EIF2S3 PE=1 SV=3 6.11 2384.7 - 168449 - - - 3.8105 - 2.899 0.641 - 752.6 1 2 0 0.0058 14 0 0 0 4.45E+06 4.52E+06 - - - 6.4446 0.9998 221125_WJC_METTL3_EV_vs_WT_F05.12341.12341.2 0.000303 26-Oct K.TSSLDPNDQVAMGR[166.11].Q "sp|Q9NY61|AATF_HUMAN,tr|A0A7P0T868|A0A7P0T868_HUMAN,tr|A0A0J9YWE9|A0A0J9YWE9_HUMAN,tr|A0A7P0TAR0|A0A7P0TAR0_HUMAN,tr|A0A087WWS8|A0A087WWS8_HUMAN,tr|A0A7P0TBI0|A0A7P0TBI0_HUMAN,tr|A0A7P0Z4P2|A0A7P0Z4P2_HUMAN,tr|A0A087WTH8|A0A087WTH8_HUMAN" 8 1499.6914 1.05 64401 12341 2 1499.69252 750.853 Protein AATF OS=Homo sapiens OX=9606 GN=AATF PE=1 SV=1 4.21 2384.8 - 164762 - - - 0.7628 - 1.978 0.533 - 225 1 2 0 0.0011 14 0 0 0 2.79E+06 2.66E+06 - - - 4.689 0.9997 221125_WJC_METTL3_EV_vs_WT_F05.12346.12346.3 0.00115 Aug-52 K.FLETESHPSIPPPK[136.11].L "sp|Q15643|TRIPB_HUMAN,tr|H0YJ97|H0YJ97_HUMAN" 2 1585.8232 1.47 64405 12346 3 1585.825569 529.615 Thyroid receptor-interacting protein 11 OS=Homo sapiens OX=9606 GN=TRIP11 PE=1 SV=3 5.4 2385.5 - 528444 - - - 1.5197 - 1.444 0.439 - 50.3 1 2 0 0.0024 14 0 0 0 2.75E+07 1.87E+07 - - - 4.4102 1 221125_WJC_METTL3_EV_vs_WT_F05.12347.12347.3 3.67E-06 Dec-48 K.GEHPGLSIGDVAK[136.11].K "sp|B2RPK0|HGB1A_HUMAN,sp|P09429|HMGB1_HUMAN,tr|Q5T7C4|Q5T7C4_HUMAN" 3 1286.671 0.47 64406 12347 3 1286.670372 429.8976 Putative high mobility group protein B1-like 1 OS=Homo sapiens OX=9606 GN=HMGB1P1 PE=5 SV=1 5.32 2385.5 - 3.39E+06 - - - -0.4997 - 2.42 0.516 - 262.3 1 2 0 -0.0006 13 0 0 0 4.49E+07 9.49E+07 - - - 6.6889 1 221125_WJC_METTL3_EV_vs_WT_F05.12349.12349.3 6.38E-13 19/56 R.REMEAQQAALDPALK.Q "sp|P39880|CUX1_HUMAN,tr|A0A2R8Y852|A0A2R8Y852_HUMAN,tr|A0A2R8YDI1|A0A2R8YDI1_HUMAN" 3 1669.8458 1.28 64408 12349 3 1669.8448 557.6225 Homeobox protein cut-like 1 OS=Homo sapiens OX=9606 GN=CUX1 PE=1 SV=3 4.68 2385.7 - 638490 - - - -0.5719 - 3.67 0.59 - 601.3 1 2 0 -0.001 15 0 0 0 4.92E+06 3.85E+06 - - - 8.5103 0.9999 221125_WJC_METTL3_EV_vs_WT_F05.12351.12351.3 0.000491 13/64 K.VMTVNYNTHGELGEGAR.K "sp|P82663|RT25_HUMAN,tr|E7EPW2|E7EPW2_HUMAN" 2 1846.8632 6.03 64410 12351 3 1846.86682 616.6283 "28S ribosomal protein S25, mitochondrial OS=Homo sapiens OX=9606 GN=MRPS25 PE=1 SV=1" 5.4 2386 - 380714 - - - 1.9622 - 2.17 0.449 - 135.1 1 2 0 0.0036 17 0 0 0 2.52E+07 4.17E+06 - - - 5.5021 0.9968 221125_WJC_METTL3_EV_vs_WT_F05.12352.12352.3 3.64E-07 15/44 L.RNPEAALSPTFR[166.11].S "sp|Q86U44|MTA70_HUMAN,tr|B4E349|B4E349_HUMAN,tr|F5H6D8|F5H6D8_HUMAN,tr|B4DTN4|B4DTN4_HUMAN" 4 1367.7185 - 64411 12352 3 1367.721509 456.9134 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 9.6 2386.1 - 351240 - - - 2.1869 - 3.335 0.517 - 470.6 1 1 0 0.003 12 0 0 0 - - - - - 7.6418 0.9999 221125_WJC_METTL3_EV_vs_WT_F05.12353.12353.2 6.47E-07 24-Dec R.QTAPSGLSTLPQR[166.11].V "sp|Q96GD4|AURKB_HUMAN,tr|J3KRF8|J3KRF8_HUMAN,tr|J3KTD6|J3KTD6_HUMAN" 3 1364.7287 1.1 64412 12353 2 1364.728485 683.3717 Aurora kinase B OS=Homo sapiens OX=9606 GN=AURKB PE=1 SV=3 9.75 2386.3 - 262442 - - - -0.1927 - 2.356 0.553 - 500.2 1 2 0 -0.0003 13 0 0 0 5.07E+06 4.63E+06 - - - 5.3248 1 221125_WJC_METTL3_EV_vs_WT_F05.12360.12360.3 2.28E-05 15/48 R.TIVITSHPGQIVK.H sp|P31689|DNJA1_HUMAN 1 1391.8137 0.43 64418 12360 3 1391.813637 464.9452 DnaJ homolog subfamily A member 1 OS=Homo sapiens OX=9606 GN=DNAJA1 PE=1 SV=2 8.44 2387.1 - 1.42E+06 - - - -0.0093 - 2.906 0.453 - 198.7 1 2 0 0 13 0 0 0 9.08E+06 2.12E+07 - - - 6.4828 0.9982 221125_WJC_METTL3_EV_vs_WT_F05.12362.12362.3 0.00549 18/44 L.R[166.11]NPEAALSPTFR[166.11].S "sp|Q86U44|MTA70_HUMAN,tr|B4E349|B4E349_HUMAN,tr|F5H6D8|F5H6D8_HUMAN,tr|B4DTN4|B4DTN4_HUMAN" 4 1377.7268 0.03 64420 12362 3 1377.727066 460.2495 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 9.6 2387.3 - 1.36E+06 - - - 0.2018 - 3.383 0.48 - 793.5 1 1 0 0.0003 12 0 0 0 9.15E+05 3.34E+07 - - - 7.2697 1 221125_WJC_METTL3_EV_vs_WT_F05.12364.12364.4 0.000216 18/72 K.LVEHGLNETIHIR.G sp|Q7Z3B4|NUP54_HUMAN 1 1529.8314 1.97 64422 12364 4 1529.831213 383.4651 Nucleoporin p54 OS=Homo sapiens OX=9606 GN=NUP54 PE=1 SV=2 6 2387.6 - 859911 - - - -0.1386 - 3.128 0.484 - 305.4 1 2 0 -0.0002 13 0 0 0 2.53E+07 1.28E+07 - - - 3.8615 0.9998 221125_WJC_METTL3_EV_vs_WT_F05.12365.12365.2 4.36E-06 13/24 K.GEHPGLSIGDVAK[136.11].K "sp|B2RPK0|HGB1A_HUMAN,sp|P09429|HMGB1_HUMAN,tr|Q5T7C4|Q5T7C4_HUMAN" 3 1286.671 0.23 64423 12365 2 1286.669932 644.3428 Putative high mobility group protein B1-like 1 OS=Homo sapiens OX=9606 GN=HMGB1P1 PE=5 SV=1 5.32 2387.7 - 803116 - - - -0.8417 - 2.289 0.415 - 360.1 1 2 0 -0.0011 13 0 0 0 2.62E+06 1.16E+07 - - - 4.2312 1 221125_WJC_METTL3_EV_vs_WT_F05.12366.12366.3 7.97E-05 19/64 K.VMTVNYNTHGELGEGAR[166.11].K "sp|P82663|RT25_HUMAN,tr|E7EPW2|E7EPW2_HUMAN" 2 1856.8715 4.74 64424 12366 3 1856.873169 619.9644 "28S ribosomal protein S25, mitochondrial OS=Homo sapiens OX=9606 GN=MRPS25 PE=1 SV=1" 5.4 2387.8 - 704068 - - - 0.9171 - 3.528 0.541 - 446.8 1 2 0 0.0017 17 0 0 0 1.98E+07 4.17E+06 - - - 7.7561 1 221125_WJC_METTL3_EV_vs_WT_F05.12368.12368.2 3.88E-08 16/26 K.VGQEIEVRPGIVSK.D sp|P41091|IF2G_HUMAN 1 1509.8515 0.98 64426 12368 2 1509.853318 755.933 Eukaryotic translation initiation factor 2 subunit 3 OS=Homo sapiens OX=9606 GN=EIF2S3 PE=1 SV=3 6.11 2388.1 - 520285 - - - 1.2094 - 2.711 0.635 - 574 1 2 0 0.0018 14 0 0 0 4.45E+06 4.52E+06 - - - 6.2333 1 221125_WJC_METTL3_EV_vs_WT_F05.12370.12370.4 2.98E-06 16/72 K.LVEHGLNETIHIR[166.11].G sp|Q7Z3B4|NUP54_HUMAN 1 1539.8397 1.97 64428 12370 4 1539.83899 385.9672 Nucleoporin p54 OS=Homo sapiens OX=9606 GN=NUP54 PE=1 SV=2 6 2388.3 - 467197 - - - -0.4578 - 2.76 0.476 - 196.4 1 2 0 -0.0007 13 0 0 0 2.53E+07 1.28E+07 - - - 3.7453 0.9997 221125_WJC_METTL3_EV_vs_WT_F05.12371.12371.2 7.10E-05 17/28 K.AIADTGANVVVTGGK[136.11].V "sp|P50990|TCPQ_HUMAN,tr|H7C4C8|H7C4C8_HUMAN" 2 1379.75 0.42 64429 12371 2 1379.753805 690.8823 T-complex protein 1 subunit theta OS=Homo sapiens OX=9606 GN=CCT8 PE=1 SV=4 5.88 2388.4 - 345246 - - - 2.7621 - 3.142 0.52 - 707.4 1 2 0 0.0038 15 0 0 0 7.63E+06 1.83E+07 - - - 5.6952 0.9704 221125_WJC_METTL3_EV_vs_WT_F05.12373.12373.2 2.41E-07 15/24 V.GQEIEVR[166.11]PGIVSK[136.11].D sp|P41091|IF2G_HUMAN 1 1428.8055 1.22 64431 12373 2 1428.810426 715.4101 Eukaryotic translation initiation factor 2 subunit 3 OS=Homo sapiens OX=9606 GN=EIF2S3 PE=1 SV=3 6.14 2388.7 - 264487 - - - 3.414 - 3.147 0.505 - 867.3 1 1 0 0.0049 13 0 0 0 1.67E+06 1.38E+06 - - - 5.7118 0.9993 221125_WJC_METTL3_EV_vs_WT_F05.12377.12377.3 0.000311 Oct-44 R.LMEEIMSEK[136.11]ENK[136.11].T "sp|P17844|DDX5_HUMAN,tr|A0A7I2V5F5|A0A7I2V5F5_HUMAN,tr|J3QSF1|J3QSF1_HUMAN,tr|A0A7I2V507|A0A7I2V507_HUMAN,tr|J3KTA4|J3KTA4_HUMAN,tr|A0A0G2JLI4|A0A0G2JLI4_HUMAN,tr|A0A7I2V2S0|A0A7I2V2S0_HUMAN" 7 1495.7233 1.54 64433 12377 3 1495.725632 499.5817 Probable ATP-dependent RNA helicase DDX5 OS=Homo sapiens OX=9606 GN=DDX5 PE=1 SV=1 4.49 2389.2 - 1.72E+06 - - - 1.5477 - 2.055 0.412 - 97.7 1 2 1 0.0023 12 0 0 0 5.38E+07 3.49E+07 - - - 5.1292 1 221125_WJC_METTL3_EV_vs_WT_F05.12379.12379.3 6.77E-06 16/60 K.KAEIGIAMGSGTAVAK.T "sp|P16615|AT2A2_HUMAN,sp|Q93084|AT2A3_HUMAN,sp|O14983|AT2A1_HUMAN,tr|H7C5W9|H7C5W9_HUMAN" 4 1502.8127 1.5 64435 12379 3 1502.814841 501.9448 Sarcoplasmic\endoplasmic reticulum calcium ATPase 2 OS=Homo sapiens OX=9606 GN=ATP2A2 PE=1 SV=1 8.59 2389.3 - 820838 - - - 1.4486 - 3.156 0.523 - 451.4 1 2 0 0.0022 16 0 0 0 8.99E+06 5.98E+06 - - - 7.3193 1 221125_WJC_METTL3_EV_vs_WT_F05.12382.12382.3 5.26E-06 Dec-60 K.K[136.11]AEIGIAMGSGTAVAK[136.11].T "sp|P16615|AT2A2_HUMAN,sp|Q93084|AT2A3_HUMAN,sp|O14983|AT2A1_HUMAN,tr|H7C5W9|H7C5W9_HUMAN" 4 1518.8411 1.93 64438 12382 3 1518.839458 507.2876 Sarcoplasmic\endoplasmic reticulum calcium ATPase 2 OS=Homo sapiens OX=9606 GN=ATP2A2 PE=1 SV=1 8.59 2389.6 - 722209 - - - -1.0574 - 2.773 0.516 - 231.1 1 2 0 -0.0016 16 0 0 0 1.14E+07 5.88E+06 - - - 6.9094 1 221125_WJC_METTL3_EV_vs_WT_F05.12383.12383.3 0.000508 15/48 K.LVEHGLNETIHIR[166.11].G sp|Q7Z3B4|NUP54_HUMAN 1 1539.8397 1.4 64439 12383 3 1539.842611 514.2872 Nucleoporin p54 OS=Homo sapiens OX=9606 GN=NUP54 PE=1 SV=2 6 2389.7 - 641488 - - - 1.8937 - 3.112 0.461 - 354.3 1 2 0 0.0029 13 0 0 0 1.17E+07 8.37E+06 - - - 6.7569 0.9982 221125_WJC_METTL3_EV_vs_WT_F05.12384.12384.3 0.022 Nov-40 K.TVTFANDLKPK.V sp|Q70UQ0|IKIP_HUMAN 1 1232.6765 1.09 64440 12384 3 1232.67713 411.8994 Inhibitor of nuclear factor kappa-B kinase-interacting protein OS=Homo sapiens OX=9606 GN=IKBIP PE=1 SV=1 8.26 2389.8 - 574741 - - - 0.5208 - 1.658 0.263 - 115.3 1 2 0 0.0006 11 0 0 0 3.61E+06 3.32E+06 - - - 2.9084 1 221125_WJC_METTL3_EV_vs_WT_F05.12385.12385.2 6.51E-06 22-Dec R.C[160.03]ESAPGC[160.03]GVWQR[166.11].P "sp|P27824|CALX_HUMAN,tr|A0A7P0T937|A0A7P0T937_HUMAN,tr|A0A7P0T840|A0A7P0T840_HUMAN,tr|A0A7P0TB65|A0A7P0TB65_HUMAN,tr|A0A7P0TAE9|A0A7P0TAE9_HUMAN,tr|D6RGY2|D6RGY2_HUMAN,tr|A0A7P0T8G1|A0A7P0T8G1_HUMAN,tr|A0A7P0Z4D6|A0A7P0Z4D6_HUMAN,tr|A0A7P0Z484|A0A7P0Z484_HUMAN,tr|A0A7P0TAR9|A0A7P0TAR9_HUMAN,tr|A0A7P0T9L0|A0A7P0T9L0_HUMAN" 11 1415.595 1.1 64441 12385 2 1415.593841 708.8048 Calnexin OS=Homo sapiens OX=9606 GN=CANX PE=1 SV=2 5.99 2390 - 485943 - - - -0.8004 - 2.273 0.612 - 441.5 1 1 0 -0.0011 12 0 0 0 7.36E+06 6.66E+06 - - - 5.7213 0.9947 221125_WJC_METTL3_EV_vs_WT_F05.12387.12387.2 0.0012 22-Oct R.LMEEIMSEK[136.11]ENK[136.11].T "sp|P17844|DDX5_HUMAN,tr|A0A7I2V5F5|A0A7I2V5F5_HUMAN,tr|J3QSF1|J3QSF1_HUMAN,tr|A0A7I2V507|A0A7I2V507_HUMAN,tr|J3KTA4|J3KTA4_HUMAN,tr|A0A0G2JLI4|A0A0G2JLI4_HUMAN,tr|A0A7I2V2S0|A0A7I2V2S0_HUMAN" 7 1495.7233 3.05 64443 12387 2 1495.726449 748.8689 Probable ATP-dependent RNA helicase DDX5 OS=Homo sapiens OX=9606 GN=DDX5 PE=1 SV=1 4.49 2390.2 - 254504 - - - 2.094 - 2.271 0.398 - 296.8 1 2 1 0.0031 12 0 0 0 8.49E+06 2.78E+06 - - - 4.1378 0.9999 221125_WJC_METTL3_EV_vs_WT_F05.12388.12388.3 2.18E-06 Dec-56 K.LHAVNAEEC[160.03]NVLQGR.W "sp|O75521|ECI2_HUMAN,tr|A0A0C4DGA2|A0A0C4DGA2_HUMAN" 2 1708.8315 0.99 64444 12388 3 1708.825284 570.6178 Enoyl-CoA delta isomerase 2 OS=Homo sapiens OX=9606 GN=ECI2 PE=1 SV=4 5.4 2390.4 - 226390 - - - -3.6387 - 2.607 0.533 - 175.3 1 2 0 -0.0062 15 0 0 0 1.95E+06 1.96E+06 - - - 6.981 0.8664 221125_WJC_METTL3_EV_vs_WT_F05.12391.12391.3 0.00897 Aug-44 L.HSLLPASNLAGK[136.11].E "tr|E9PAU2|E9PAU2_HUMAN,tr|A0A087WZ13|A0A087WZ13_HUMAN" 2 1214.6863 2.52 64447 12391 3 1214.684789 405.9027 Ribonucleoprotein PTB-binding 1 OS=Homo sapiens OX=9606 GN=RAVER1 PE=1 SV=1 8.76 2390.7 - 138188 - - - -1.2201 - 1.767 0.269 - 82.3 1 1 0 -0.0015 12 0 0 0 2.67E+06 1.06E+06 - - - 3.1166 0.9997 221125_WJC_METTL3_EV_vs_WT_F05.12392.12392.2 0.000118 28-May K.EQGPYETYEGSPVSK[136.11].G "sp|P23921|RIR1_HUMAN,tr|E9PL69|E9PL69_HUMAN" 2 1677.7613 0.37 64448 12392 2 1677.759395 839.8879 Ribonucleoside-diphosphate reductase large subunit OS=Homo sapiens OX=9606 GN=RRM1 PE=1 SV=1 4.25 2390.9 - 128517 - - - -1.1629 - 1.526 0.496 - 52.2 1 2 0 -0.002 15 0 0 0 8.72E+05 2.39E+06 - - - 3.7429 0.9824 221125_WJC_METTL3_EV_vs_WT_F05.12393.12393.2 0.255 24-May K.QAQELVDENDGLK.M "sp|Q96ST8|CEP89_HUMAN,tr|A0A0C4DGP8|A0A0C4DGP8_HUMAN,tr|K7EJF0|K7EJF0_HUMAN" 3 1457.6998 -1 64449 12393 2 1457.701742 729.8572 Centrosomal protein of 89 kDa OS=Homo sapiens OX=9606 GN=CEP89 PE=1 SV=3 3.92 2391 - 126629 - - - 1.3309 - 0.986 0.236 - 22.5 3 2 0 0.0019 13 0 0 0 0.00E+00 0.00E+00 - - - 0.5342 0.9961 221125_WJC_METTL3_EV_vs_WT_F05.12395.12395.3 0.0382 Dec-40 R.TKIDPSALVQK.L "sp|Q9NSI2|SLX9_HUMAN,tr|C9JJU7|C9JJU7_HUMAN" 2 1198.6921 1.92 64450 12395 3 1198.692435 400.5713 Ribosome biogenesis protein SLX9 homolog OS=Homo sapiens OX=9606 GN=SLX9 PE=1 SV=2 8.26 2391.4 - 523284 - - - 0.2478 - 2.009 0.26 - 161.3 1 2 1 0.0003 11 0 0 0 1.95E+07 1.01E+07 - - - 3.4205 0.9999 221125_WJC_METTL3_EV_vs_WT_F05.12397.12397.2 6.41E-08 18-Nov K.DQYANYVVQK[136.11].M "sp|Q8TB72|PUM2_HUMAN,sp|Q14671|PUM1_HUMAN,tr|Q5T1Z8|Q5T1Z8_HUMAN,tr|H0YDK8|H0YDK8_HUMAN,tr|A0A0C4DG68|A0A0C4DG68_HUMAN,tr|H0YEH2|H0YEH2_HUMAN,tr|Q5T1Z4|Q5T1Z4_HUMAN,tr|E9PR38|E9PR38_HUMAN" 8 1234.6074 0.27 64451 12397 2 1234.606801 618.311 Pumilio homolog 2 OS=Homo sapiens OX=9606 GN=PUM2 PE=1 SV=2 5.83 2391.6 - 5.22E+06 - - - -0.4463 - 2.21 0.582 - 470.1 1 2 0 -0.0006 10 0 0 0 4.31E+07 1.57E+08 - - - 5.553 0.9983 221125_WJC_METTL3_EV_vs_WT_F05.12398.12398.3 0.00488 Oct-44 K.ALVSEWK[136.11]EPQAK[136.11].N "sp|Q16531|DDB1_HUMAN,tr|A0A7P0TAK7|A0A7P0TAK7_HUMAN,tr|A0A7P0T870|A0A7P0T870_HUMAN,tr|A0A7P0TB30|A0A7P0TB30_HUMAN,tr|A0A7P0Z3Z5|A0A7P0Z3Z5_HUMAN,tr|F5GY55|F5GY55_HUMAN,tr|A0A7P0Z4B9|A0A7P0Z4B9_HUMAN" 7 1400.7635 0.75 64452 12398 3 1400.763915 467.9284 DNA damage-binding protein 1 OS=Homo sapiens OX=9606 GN=DDB1 PE=1 SV=1 6.19 2391.6 - 2.91E+06 - - - 0.3213 - 2.18 0.302 - 135.6 1 2 1 0.0004 12 0 0 0 1.75E+07 2.34E+07 - - - 4.0671 1 221125_WJC_METTL3_EV_vs_WT_F05.12400.12400.2 0.00106 15/22 R.LMEEIMSEKENK.T "sp|P17844|DDX5_HUMAN,tr|A0A7I2V5F5|A0A7I2V5F5_HUMAN,tr|J3QSF1|J3QSF1_HUMAN,tr|A0A7I2V507|A0A7I2V507_HUMAN,tr|J3KTA4|J3KTA4_HUMAN,tr|A0A0G2JLI4|A0A0G2JLI4_HUMAN,tr|A0A7I2V2S0|A0A7I2V2S0_HUMAN" 7 1479.6949 2.65 64454 12400 2 1479.694385 740.8547 Probable ATP-dependent RNA helicase DDX5 OS=Homo sapiens OX=9606 GN=DDX5 PE=1 SV=1 4.49 2391.9 - 659175 - - - -0.3595 - 2.883 0.536 - 817.1 1 2 1 -0.0005 12 0 0 0 7.37E+06 2.78E+06 - - - 5.7857 1 221125_WJC_METTL3_EV_vs_WT_F05.12401.12401.3 9.74E-12 18/56 K.YLEHGEYEGNLYGTK.L "sp|Q9NZW5|PALS2_HUMAN,tr|B8ZZG1|B8ZZG1_HUMAN" 2 1771.8053 1.75 64455 12401 3 1771.80603 591.6091 Protein PALS2 OS=Homo sapiens OX=9606 GN=PALS2 PE=1 SV=2 4.75 2392 - 609857 - - - 0.3951 - 2.974 0.649 - 268.7 1 2 0 0.0007 15 0 0 0 9.74E+06 5.56E+06 - - - 8.6195 0.9989 221125_WJC_METTL3_EV_vs_WT_F05.12402.12402.3 2.77E-05 Nov-44 R.LR[166.11]ENELTYYC[160.03]C[160.03]K[136.11].K "sp|P13987|CD59_HUMAN,tr|H0YET2|H0YET2_HUMAN,tr|E9PNW4|E9PNW4_HUMAN,tr|A0A2U3TZL5|A0A2U3TZL5_HUMAN" 4 1665.761 0.8 64456 12402 3 1665.756063 556.2609 CD59 glycoprotein OS=Homo sapiens OX=9606 GN=CD59 PE=1 SV=1 6.13 2392.1 - 567140 - - - -2.9536 - 2.253 0.433 - 205.6 1 2 1 -0.0049 12 0 0 0 3.49E+06 4.38E+06 - - - 5.6176 0.9998 221125_WJC_METTL3_EV_vs_WT_F05.12403.12403.2 0.0004 26-Oct K.EALEPSGENVIQNK.E sp|O75477|ERLN1_HUMAN 1 1526.7577 1.89 64457 12403 2 1526.757625 764.3861 Erlin-1 OS=Homo sapiens OX=9606 GN=ERLIN1 PE=1 SV=2 4.25 2392.3 - 565492 - - - -0.017 - 2.259 0.456 - 259.9 1 2 0 0 14 0 0 0 6.58E+06 3.47E+06 - - - 4.454 0.9999 221125_WJC_METTL3_EV_vs_WT_F05.12404.12404.3 0.000836 Oct-32 K.R[166.11]EEDFPSLR[166.11].E sp|P51948|MAT1_HUMAN 1 1167.5787 0.69 64458 12404 3 1167.578766 390.2002 CDK-activating kinase assembly factor MAT1 OS=Homo sapiens OX=9606 GN=MNAT1 PE=1 SV=1 4.68 2392.4 - 482372 - - - 0.0343 - 1.973 0.409 - 148.2 1 2 0 0 9 0 0 0 2.91E+06 4.21E+06 - - - 5.148 0.999 221125_WJC_METTL3_EV_vs_WT_F05.12405.12405.2 0.0091 22-Aug K.GKPDLNTALPVR.Q "sp|O95983|MBD3_HUMAN,tr|A0A087X1H1|A0A087X1H1_HUMAN,tr|K7EIE8|K7EIE8_HUMAN,tr|A0A087WT34|A0A087WT34_HUMAN,tr|A0A0A0MTS6|A0A0A0MTS6_HUMAN" 5 1279.7248 1.72 64459 12405 2 1279.722012 640.8697 Methyl-CpG-binding domain protein 3 OS=Homo sapiens OX=9606 GN=MBD3 PE=1 SV=1 8.75 2392.5 - 477252 - - - -2.2059 - 1.734 0.378 - 176.5 1 2 0 -0.0028 12 0 0 0 1.03E+07 6.01E+06 - - - 3.2803 0.9997 221125_WJC_METTL3_EV_vs_WT_F05.12406.12406.3 0.00562 Oct-44 K.DHLYGTLDPNTR[166.11].E "sp|Q14204|DYHC1_HUMAN,tr|A0A7P0T8N2|A0A7P0T8N2_HUMAN,tr|A0A7P0T9C4|A0A7P0T9C4_HUMAN,tr|A0A7P0TBJ7|A0A7P0TBJ7_HUMAN,tr|A0A804HHY6|A0A804HHY6_HUMAN,tr|A0A7P0T9K2|A0A7P0T9K2_HUMAN,tr|A0A7P0TB64|A0A7P0TB64_HUMAN,tr|A0A2R8Y706|A0A2R8Y706_HUMAN,tr|A0A7P0T916|A0A7P0T916_HUMAN,tr|A0A7P0TB75|A0A7P0TB75_HUMAN,tr|A0A7P0T8W5|A0A7P0T8W5_HUMAN,tr|A0A7P0T9S3|A0A7P0T9S3_HUMAN,tr|A0A7P0TAF3|A0A7P0TAF3_HUMAN,tr|A0A7P0T9F1|A0A7P0T9F1_HUMAN,tr|A0A7P0TAW9|A0A7P0TAW9_HUMAN,tr|A0A2R8YGC7|A0A2R8YGC7_HUMAN,tr|A0A7P0TA13|A0A7P0TA13_HUMAN,tr|A0A7P0T934|A0A7P0T934_HUMAN,tr|A0A7P0TAV5|A0A7P0TAV5_HUMAN,tr|A0A7P0T7V5|A0A7P0T7V5_HUMAN,tr|A0A7P0T9R4|A0A7P0T9R4_HUMAN,tr|A0A2R8Y5T0|A0A2R8Y5T0_HUMAN,tr|A0A7P0T990|A0A7P0T990_HUMAN,tr|A0A7P0T942|A0A7P0T942_HUMAN,tr|A0A2R8YFZ7|A0A2R8YFZ7_HUMAN,tr|A0A7P0T825|A0A7P0T825_HUMAN,tr|A0A2R8Y6H2|A0A2R8Y6H2_HUMAN,tr|A0A7P0TAM4|A0A7P0TAM4_HUMAN" 28 1410.6767 6.03 64460 12406 3 1410.67643 471.2328 Cytoplasmic dynein 1 heavy chain 1 OS=Homo sapiens OX=9606 GN=DYNC1H1 PE=1 SV=5 5.21 2392.7 - 462421 - - - -0.1999 - 2.016 0.337 - 162.7 1 2 0 -0.0003 12 0 0 0 3.04E+07 5.04E+06 - - - 4.2405 0.9999 221125_WJC_METTL3_EV_vs_WT_F05.12408.12408.2 5.05E-05 13/26 K.EALEPSGENVIQNK[136.11].E sp|O75477|ERLN1_HUMAN 1 1534.7719 1.89 64462 12408 2 1534.771011 768.3932 Erlin-1 OS=Homo sapiens OX=9606 GN=ERLIN1 PE=1 SV=2 4.25 2392.9 - 389058 - - - -0.5473 - 2.587 0.541 - 495.9 1 2 0 -0.0008 14 0 0 0 6.58E+06 3.47E+06 - - - 5.4218 0.9661 221125_WJC_METTL3_EV_vs_WT_F05.12413.12413.3 0.00894 Jul-56 S.ITQDYHLDEQDAEGR.L sp|Q8NAX2|KDF1_HUMAN 1 1788.7915 2.76 64467 12413 3 1788.793817 597.2711 Keratinocyte differentiation factor 1 OS=Homo sapiens OX=9606 GN=KDF1 PE=1 SV=2 4.1 2393.6 - 293383 - - - 1.3115 - 1.477 0.43 - 67.6 1 1 0 0.0023 15 0 0 0 1.71E+06 6.20E+05 - - - 4.3511 0.9992 221125_WJC_METTL3_EV_vs_WT_F05.12415.12415.2 0.0023 22-Oct K.LQNLQLQPGNAK.L sp|P22307|SCP2_HUMAN 1 1322.7306 1 64469 12415 2 1322.730058 662.3726 Sterol carrier protein 2 OS=Homo sapiens OX=9606 GN=SCP2 PE=1 SV=2 8.75 2393.8 - 249349 - - - -0.4468 - 2.002 0.227 - 284 1 2 0 -0.0006 12 0 0 0 2.64E+06 2.63E+06 - - - 2.5439 0.9998 221125_WJC_METTL3_EV_vs_WT_F05.12416.12416.2 0.00097 22-Oct K.LQNLQLQPGNAK[136.11].L sp|P22307|SCP2_HUMAN 1 1330.7448 1 64470 12416 2 1330.744936 666.3797 Sterol carrier protein 2 OS=Homo sapiens OX=9606 GN=SCP2 PE=1 SV=2 8.75 2393.9 - 235260 - - - 0.0654 - 1.938 0.44 - 275.4 1 2 0 0.0001 12 0 0 0 2.64E+06 2.63E+06 - - - 4.0317 0.9999 221125_WJC_METTL3_EV_vs_WT_F05.12420.12420.3 0.000883 13/44 K.GK[136.11]PDLNTALPVR[166.11].Q "sp|O95983|MBD3_HUMAN,tr|A0A087X1H1|A0A087X1H1_HUMAN,tr|K7EIE8|K7EIE8_HUMAN,tr|A0A087WT34|A0A087WT34_HUMAN,tr|A0A0A0MTS6|A0A0A0MTS6_HUMAN" 5 1297.7473 1.55 64472 12420 3 1297.747865 433.5897 Methyl-CpG-binding domain protein 3 OS=Homo sapiens OX=9606 GN=MBD3 PE=1 SV=1 8.75 2394.4 - 4.07E+06 - - - 0.4315 - 2.378 0.358 - 234.4 1 2 0 0.0006 12 0 0 0 7.74E+07 4.98E+07 - - - 4.9323 0.9783 221125_WJC_METTL3_EV_vs_WT_F05.12423.12423.2 0.000189 13/16 R.SGKYDLDFK.S "sp|P06733|ENOA_HUMAN,tr|A0A2R8Y6G6|A0A2R8Y6G6_HUMAN" 2 1071.5237 1.4 64475 12423 2 1071.528036 536.7691 Alpha-enolase OS=Homo sapiens OX=9606 GN=ENO1 PE=1 SV=2 5.68 2394.6 - 1.25E+06 - - - 4.069 - 1.811 0.453 - 537 1 2 1 0.0044 9 0 0 0 1.91E+07 1.37E+07 - - - 4.1036 1 221125_WJC_METTL3_EV_vs_WT_F05.12424.12424.3 5.35E-05 13/36 R.KEMEQLVLDK.K sp|Q96A49|SYAP1_HUMAN 1 1231.6482 1.22 64476 12424 3 1231.647533 411.5567 Synapse-associated protein 1 OS=Homo sapiens OX=9606 GN=SYAP1 PE=1 SV=1 4.68 2394.7 - 1.04E+06 - - - -0.561 - 2.397 0.467 - 346.6 1 2 0 -0.0007 10 0 0 0 4.27E+07 3.51E+07 - - - 6.2995 0.9998 221125_WJC_METTL3_EV_vs_WT_F05.12429.12429.2 0.000302 16/18 R.K[136.11]EMEQLVLDK[136.11].K sp|Q96A49|SYAP1_HUMAN 1 1247.6766 1.28 64481 12429 2 1247.678188 624.8456 Synapse-associated protein 1 OS=Homo sapiens OX=9606 GN=SYAP1 PE=1 SV=1 4.68 2395.3 - 525962 - - - 1.2535 - 3.137 0.399 - 976 1 2 0 0.0016 10 0 0 0 2.68E+07 2.10E+07 - - - 5.1787 0.9996 221125_WJC_METTL3_EV_vs_WT_F05.12431.12431.3 0.00852 16/40 R.TK[136.11]IDPSALVQK[136.11].L "sp|Q9NSI2|SLX9_HUMAN,tr|C9JJU7|C9JJU7_HUMAN" 2 1214.7205 1.92 64483 12431 3 1214.723862 405.9141 Ribosome biogenesis protein SLX9 homolog OS=Homo sapiens OX=9606 GN=SLX9 PE=1 SV=2 8.26 2395.6 - 314831 - - - 2.7364 - 2.912 0.46 - 349.3 1 2 1 0.0033 11 0 0 0 1.95E+07 1.01E+07 - - - 6.704 0.9996 221125_WJC_METTL3_EV_vs_WT_F05.12433.12433.3 0.00691 13/44 K.ILQEYITQEGHK[136.11].L "sp|Q9BXS5|AP1M1_HUMAN,tr|K7EPJ8|K7EPJ8_HUMAN,tr|E7ENJ6|E7ENJ6_HUMAN,tr|K7EJL1|K7EJL1_HUMAN,tr|A0A087WZX7|A0A087WZX7_HUMAN" 5 1465.7656 0.58 64485 12433 3 1465.765968 489.5958 AP-1 complex subunit mu-1 OS=Homo sapiens OX=9606 GN=AP1M1 PE=1 SV=3 5.4 2395.9 - 251475 - - - 0.221 - 2.037 0.307 - 237 1 2 0 0.0003 12 0 0 0 6.29E+06 1.08E+07 - - - 3.9348 0.9974 221125_WJC_METTL3_EV_vs_WT_F05.12434.12434.2 0.00285 22-Jun K.TPNPANQYQFDK[136.11].V sp|Q13769|THOC5_HUMAN 1 1429.6717 0.8 64486 12434 2 1429.668942 715.8431 THO complex subunit 5 homolog OS=Homo sapiens OX=9606 GN=THOC5 PE=1 SV=2 5.5 2396 - 150402 - - - -1.9592 - 1.25 0.344 - 77.5 1 2 0 -0.0028 12 0 0 0 1.14E+06 1.42E+06 - - - 2.168 1 221125_WJC_METTL3_EV_vs_WT_F05.12437.12437.2 1.98E-08 20-Dec K.HPENYDLATLK.W "sp|P78347|GTF2I_HUMAN,sp|Q86UP8|GTD2A_HUMAN,sp|Q6EKJ0|GTD2B_HUMAN,tr|A0A494C1N8|A0A494C1N8_HUMAN,tr|A0A087WW90|A0A087WW90_HUMAN,tr|A0A0D9SF80|A0A0D9SF80_HUMAN,tr|A0A494C0I1|A0A494C0I1_HUMAN,tr|A0A494C1K3|A0A494C1K3_HUMAN" 8 1299.6459 1.51 64488 12437 2 1299.649656 650.8302 General transcription factor II-I OS=Homo sapiens OX=9606 GN=GTF2I PE=1 SV=2 5.32 2396.4 - 1.20E+06 - - - 2.8777 - 2.53 0.577 - 412.5 1 2 0 0.0037 11 0 0 0 5.84E+08 3.88E+08 - - - 5.8126 1 221125_WJC_METTL3_EV_vs_WT_F05.12438.12438.3 4.73E-05 Nov-40 K.HPENYDLATLK[136.11].W "sp|P78347|GTF2I_HUMAN,sp|Q86UP8|GTD2A_HUMAN,sp|Q6EKJ0|GTD2B_HUMAN,tr|A0A494C1N8|A0A494C1N8_HUMAN,tr|A0A087WW90|A0A087WW90_HUMAN,tr|A0A0D9SF80|A0A0D9SF80_HUMAN,tr|A0A494C0I1|A0A494C0I1_HUMAN,tr|A0A494C1K3|A0A494C1K3_HUMAN" 8 1307.6601 1.55 64489 12438 3 1307.660064 436.894 General transcription factor II-I OS=Homo sapiens OX=9606 GN=GTF2I PE=1 SV=2 5.32 2396.5 - 1.42E+06 - - - -0.0398 - 1.861 0.519 - 173 1 2 0 -0.0001 11 0 0 0 5.84E+08 3.77E+08 - - - 6.0908 0.9982 221125_WJC_METTL3_EV_vs_WT_F05.12439.12439.3 0.0295 Oct-52 K.LAQSNGWGVMVSHR.S sp|P13929|ENOB_HUMAN 1 1540.7569 1.44 64490 12439 3 1540.757777 514.5929 Beta-enolase OS=Homo sapiens OX=9606 GN=ENO3 PE=1 SV=5 9.76 2396.6 - 1.74E+06 - - - 0.5822 - 1.824 0.247 - 147.1 1 2 0 0.0009 14 0 0 0 2.07E+07 1.44E+07 - - - 2.8908 1 221125_WJC_METTL3_EV_vs_WT_F05.12440.12440.2 2.08E-09 15/20 K.HPENYDLATLK[136.11].W "sp|P78347|GTF2I_HUMAN,sp|Q86UP8|GTD2A_HUMAN,sp|Q6EKJ0|GTD2B_HUMAN,tr|A0A494C1N8|A0A494C1N8_HUMAN,tr|A0A087WW90|A0A087WW90_HUMAN,tr|A0A0D9SF80|A0A0D9SF80_HUMAN,tr|A0A494C0I1|A0A494C0I1_HUMAN,tr|A0A494C1K3|A0A494C1K3_HUMAN" 8 1307.6601 1.51 64491 12440 2 1307.660486 654.8373 General transcription factor II-I OS=Homo sapiens OX=9606 GN=GTF2I PE=1 SV=2 5.32 2396.7 - 750022 - - - 0.2829 - 2.885 0.604 - 672.2 1 2 0 0.0004 11 0 0 0 5.84E+08 3.88E+08 - - - 6.3683 0.9976 221125_WJC_METTL3_EV_vs_WT_F05.12442.12442.2 0.00401 20-Nov K.NTLTQTTENLR.R sp|P15924|DESP_HUMAN 1 1289.6575 8.49 64493 12442 2 1289.658552 645.836 Desmoplakin OS=Homo sapiens OX=9606 GN=DSP PE=1 SV=3 6 2397 - 620594 - - - 0.7824 - 2.036 0.113 - 441.9 1 2 0 0.001 11 0 0 0 3.41E+06 4.02E+05 - - - 1.7987 0.9996 221125_WJC_METTL3_EV_vs_WT_F05.12443.12443.3 0.00511 13/44 K.ILQEYITQEGHK.L "sp|Q9BXS5|AP1M1_HUMAN,tr|K7EPJ8|K7EPJ8_HUMAN,tr|E7ENJ6|E7ENJ6_HUMAN,tr|K7EJL1|K7EJL1_HUMAN,tr|A0A087WZX7|A0A087WZX7_HUMAN" 5 1457.7514 0.55 64494 12443 3 1457.753495 486.9244 AP-1 complex subunit mu-1 OS=Homo sapiens OX=9606 GN=AP1M1 PE=1 SV=3 5.4 2397.1 - 481474 - - - 1.407 - 2.29 0.299 - 238.9 1 2 0 0.0021 12 0 0 0 5.80E+06 1.06E+07 - - - 4.1696 0.9949 221125_WJC_METTL3_EV_vs_WT_F05.12444.12444.2 0.0176 20-Sep R.TKIDPSALVQK.L "sp|Q9NSI2|SLX9_HUMAN,tr|C9JJU7|C9JJU7_HUMAN" 2 1198.6921 2.22 64495 12444 2 1198.691946 600.3533 Ribosome biogenesis protein SLX9 homolog OS=Homo sapiens OX=9606 GN=SLX9 PE=1 SV=2 8.26 2397.2 - 326854 - - - -0.1602 - 1.923 0.311 - 196.9 1 2 1 -0.0002 11 0 0 0 5.67E+06 2.55E+06 - - - 3.1069 0.9999 221125_WJC_METTL3_EV_vs_WT_F05.12446.12446.3 0.000241 Nov-40 R.SLGTADVHFER[166.11].K "sp|Q86V81|THOC4_HUMAN,tr|E9PB61|E9PB61_HUMAN" 2 1240.6076 1.04 64497 12446 3 1240.607891 414.5431 THO complex subunit 4 OS=Homo sapiens OX=9606 GN=ALYREF PE=1 SV=3 5.3 2397.5 - 235984 - - - 0.2587 - 2.131 0.393 - 147.7 1 2 0 0.0003 11 0 0 0 1.44E+06 1.38E+06 - - - 5.0708 0.9998 221125_WJC_METTL3_EV_vs_WT_F05.12447.12447.2 6.57E-05 26-Oct K.QTGSGPLGNSYVER[166.11].Q sp|Q9UER7|DAXX_HUMAN 1 1473.7087 0.79 64498 12447 2 1473.709815 737.8616 Death domain-associated protein 6 OS=Homo sapiens OX=9606 GN=DAXX PE=1 SV=2 6 2397.6 - 235442 - - - 0.7288 - 2.059 0.472 - 322.9 1 2 0 0.0011 14 0 0 0 1.75E+06 2.22E+06 - - - 4.3392 0.9997 221125_WJC_METTL3_EV_vs_WT_F05.12451.12451.3 0.00535 Aug-40 R.NISHYEEQLVK[136.11].M "sp|P13861|KAP2_HUMAN,tr|H7C330|H7C330_HUMAN" 2 1366.6972 1.73 64500 12451 3 1366.696585 456.573 cAMP-dependent protein kinase type II-alpha regulatory subunit OS=Homo sapiens OX=9606 GN=PRKAR2A PE=1 SV=2 5.4 2398.1 - 4.03E+06 - - - -0.4719 - 1.912 0.336 - 115.9 1 2 0 -0.0006 11 0 0 0 5.72E+07 3.32E+07 - - - 4.1272 0.9997 221125_WJC_METTL3_EV_vs_WT_F05.12452.12452.2 0.000968 16-Sep R.SLVNLGGSK.S sp|P04264|K2C1_HUMAN 1 873.492 999 64501 12452 2 873.491628 437.7533 "Keratin, type II cytoskeletal 1 OS=Homo sapiens OX=9606 GN=KRT1 PE=1 SV=6" 8.47 2398.2 - 2.68E+06 - - - -0.4053 - 1.555 0.43 - 252.2 1 2 0 -0.0004 9 0 0 0 4.09E+07 0.00E+00 - - - 3.4941 1 221125_WJC_METTL3_EV_vs_WT_F05.12453.12453.3 3.23E-06 Dec-52 R.HEVASVEGDPVIMK.S "sp|Q5JPH6|SYEM_HUMAN,tr|H3BTB7|H3BTB7_HUMAN" 2 1509.7497 0.92 64502 12453 3 1509.750599 504.2572 "Probable glutamate--tRNA ligase, mitochondrial OS=Homo sapiens OX=9606 GN=EARS2 PE=1 SV=2" 4.65 2398.3 - 667142 - - - 0.5763 - 2.232 0.554 - 200.5 1 2 0 0.0009 14 0 0 0 5.25E+06 5.68E+06 - - - 6.85 1 221125_WJC_METTL3_EV_vs_WT_F05.12454.12454.2 1.74E-08 14/28 R.GGGAFVQNSQPVAVR.G sp|P33176|KINH_HUMAN 1 1485.7688 0.79 64503 12454 2 1485.76821 743.8917 Kinesin-1 heavy chain OS=Homo sapiens OX=9606 GN=KIF5B PE=1 SV=1 9.75 2398.4 - 505267 - - - -0.4139 - 2.879 0.639 - 743.7 1 2 0 -0.0006 15 0 0 0 4.84E+06 6.15E+06 - - - 6.3602 1 221125_WJC_METTL3_EV_vs_WT_F05.12457.12457.3 6.85E-10 14/52 R.HEVASVEGDPVIMK[136.11].S "sp|Q5JPH6|SYEM_HUMAN,tr|H3BTB7|H3BTB7_HUMAN" 2 1517.7639 0.97 64506 12457 3 1517.76093 506.9286 "Probable glutamate--tRNA ligase, mitochondrial OS=Homo sapiens OX=9606 GN=EARS2 PE=1 SV=2" 4.65 2398.8 - 443067 - - - -1.9759 - 2.688 0.562 - 316.8 1 2 0 -0.003 14 0 0 0 5.25E+06 5.40E+06 - - - 7.4327 0.9988 221125_WJC_METTL3_EV_vs_WT_F05.12458.12458.2 0.00752 18-Aug K.IGAVEEELNR.V "sp|P52732|KIF11_HUMAN,tr|A0A7I2YQY4|A0A7I2YQY4_HUMAN,tr|A0A7I2V3A9|A0A7I2V3A9_HUMAN,tr|A0A7I2V3V3|A0A7I2V3V3_HUMAN" 4 1128.5775 22.37 64507 12458 2 1128.580232 565.296 Kinesin-like protein KIF11 OS=Homo sapiens OX=9606 GN=KIF11 PE=1 SV=2 4.25 2398.9 - 384509 - - - 2.419 - 1.773 0.353 - 213.1 1 2 0 0.0027 10 0 0 0 2.69E+06 1.20E+05 - - - 3.2459 0.9986 221125_WJC_METTL3_EV_vs_WT_F05.12463.12463.3 0.323 Nov-36 R.K[136.11]EMEQLVLDK[136.11].K sp|Q96A49|SYAP1_HUMAN 1 1247.6766 1.21 64511 12463 3 1247.676015 416.8995 Synapse-associated protein 1 OS=Homo sapiens OX=9606 GN=SYAP1 PE=1 SV=1 4.68 2399.5 - 3.76E+06 - - - -0.4881 - 2.089 0.214 - 294.3 1 2 0 -0.0006 10 0 0 0 4.23E+07 3.50E+07 - - - 3.0772 1 221125_WJC_METTL3_EV_vs_WT_F05.12468.12468.2 3.75E-09 14/28 R.GGGAFVQNSQPVAVR[166.11].G sp|P33176|KINH_HUMAN 1 1495.7771 0.79 64516 12468 2 1495.779437 748.8958 Kinesin-1 heavy chain OS=Homo sapiens OX=9606 GN=KIF5B PE=1 SV=1 9.75 2400 - 798385 - - - 1.5657 - 3.027 0.632 - 778.9 1 2 0 0.0023 15 0 0 0 4.84E+06 6.15E+06 - - - 6.4312 0.9937 221125_WJC_METTL3_EV_vs_WT_F05.12471.12471.2 0.0612 16-Sep R.QAELAQWQK.V "sp|Q9Y2R0|COA3_HUMAN,tr|K7EPV0|K7EPV0_HUMAN" 2 1100.5615 2.68 64519 12471 2 1100.563103 551.288 "Cytochrome c oxidase assembly factor 3 homolog, mitochondrial OS=Homo sapiens OX=9606 GN=COA3 PE=1 SV=1" 6 2400.4 - 423377 - - - 1.4947 - 1.349 0.191 - 222.9 1 2 0 0.0016 9 0 0 0 3.70E+06 1.38E+06 - - - 1.3173 0.9999 221125_WJC_METTL3_EV_vs_WT_F05.12472.12472.3 0.00865 Dec-52 R.FTQDTQPHYIYSPR.E "sp|Q14204|DYHC1_HUMAN,tr|A0A7P0T8N2|A0A7P0T8N2_HUMAN,tr|A0A7P0T9C4|A0A7P0T9C4_HUMAN,tr|A0A7P0TBJ7|A0A7P0TBJ7_HUMAN,tr|A0A804HHY6|A0A804HHY6_HUMAN,tr|A0A7P0T9K2|A0A7P0T9K2_HUMAN,tr|A0A7P0TB64|A0A7P0TB64_HUMAN,tr|A0A2R8Y706|A0A2R8Y706_HUMAN,tr|A0A7P0T916|A0A7P0T916_HUMAN,tr|A0A7P0TB75|A0A7P0TB75_HUMAN,tr|A0A7P0T8W5|A0A7P0T8W5_HUMAN,tr|A0A7P0TAF3|A0A7P0TAF3_HUMAN,tr|A0A7P0T9F1|A0A7P0T9F1_HUMAN,tr|A0A7P0TAW9|A0A7P0TAW9_HUMAN,tr|A0A7P0TA13|A0A7P0TA13_HUMAN,tr|A0A7P0TAV5|A0A7P0TAV5_HUMAN,tr|A0A7P0T7V5|A0A7P0T7V5_HUMAN,tr|A0A7P0T9R4|A0A7P0T9R4_HUMAN,tr|A0A2R8Y5T0|A0A2R8Y5T0_HUMAN,tr|A0A7P0T990|A0A7P0T990_HUMAN,tr|A0A2R8YFZ7|A0A2R8YFZ7_HUMAN,tr|A0A7P0T825|A0A7P0T825_HUMAN,tr|A0A2R8Y6H2|A0A2R8Y6H2_HUMAN,tr|A0A7P0TAM4|A0A7P0TAM4_HUMAN" 24 1751.8267 0.73 64520 12472 3 1751.825726 584.9495 Cytoplasmic dynein 1 heavy chain 1 OS=Homo sapiens OX=9606 GN=DYNC1H1 PE=1 SV=5 6.74 2400.5 - 357358 - - - -0.5754 - 2.286 0.446 - 247 1 2 0 -0.001 14 0 0 0 4.67E+06 6.41E+06 - - - 5.7094 1 221125_WJC_METTL3_EV_vs_WT_F05.12475.12475.2 3.92E-11 15/30 K.VQGSDSDEEVVVATTR[166.11].L "sp|P26640|SYVC_HUMAN,tr|A0A140T936|A0A140T936_HUMAN" 2 1700.8092 0.65 64523 12475 2 1700.807456 851.4119 Valine--tRNA ligase OS=Homo sapiens OX=9606 GN=VARS1 PE=1 SV=4 3.92 2400.9 - 209719 - - - -1.0507 - 3.091 0.728 - 810.4 1 2 0 -0.0018 16 0 0 0 2.91E+06 4.47E+06 - - - 7.1919 0.9937 221125_WJC_METTL3_EV_vs_WT_F05.12478.12478.3 0.111 Dec-44 R.LMEEIMSEKENK.T "sp|P17844|DDX5_HUMAN,tr|A0A7I2V5F5|A0A7I2V5F5_HUMAN,tr|J3QSF1|J3QSF1_HUMAN,tr|A0A7I2V507|A0A7I2V507_HUMAN,tr|J3KTA4|J3KTA4_HUMAN,tr|A0A0G2JLI4|A0A0G2JLI4_HUMAN,tr|A0A7I2V2S0|A0A7I2V2S0_HUMAN" 7 1479.6949 1.54 64525 12478 3 1479.695854 494.2389 Probable ATP-dependent RNA helicase DDX5 OS=Homo sapiens OX=9606 GN=DDX5 PE=1 SV=1 4.49 2401.2 - 425387 - - - 0.6332 - 1.391 0.326 - 69 1 2 1 0.0009 12 0 0 0 5.40E+07 3.49E+07 - - - 3.0891 1 221125_WJC_METTL3_EV_vs_WT_F05.12479.12479.2 5.91E-08 15/20 R.NISHYEEQLVK.M "sp|P13861|KAP2_HUMAN,tr|H7C330|H7C330_HUMAN" 2 1358.683 1.85 64526 12479 2 1358.682769 680.3488 cAMP-dependent protein kinase type II-alpha regulatory subunit OS=Homo sapiens OX=9606 GN=PRKAR2A PE=1 SV=2 5.4 2401.3 - 1.16E+06 - - - -0.1921 - 2.975 0.596 - 868.6 1 2 0 -0.0003 11 0 0 0 9.94E+06 5.37E+06 - - - 6.3923 0.9995 221125_WJC_METTL3_EV_vs_WT_F05.12481.12481.3 0.00705 Oct-52 R.LDPFADGGK[136.11]TPDPK[136.11].M sp|O75533|SF3B1_HUMAN 1 1472.7482 1.49 64528 12481 3 1472.748607 491.9233 Splicing factor 3B subunit 1 OS=Homo sapiens OX=9606 GN=SF3B1 PE=1 SV=3 4.43 2401.5 - 1.11E+06 - - - 0.2702 - 2.05 0.415 - 79.5 1 2 1 0.0004 14 0 0 0 2.85E+07 1.92E+07 - - - 5.0744 0.9997 221125_WJC_METTL3_EV_vs_WT_F05.12485.12485.2 0.000144 22-Sep K.GK[136.11]PDLNTALPVR[166.11].Q "sp|O95983|MBD3_HUMAN,tr|A0A087X1H1|A0A087X1H1_HUMAN,tr|K7EIE8|K7EIE8_HUMAN,tr|A0A087WT34|A0A087WT34_HUMAN,tr|A0A0A0MTS6|A0A0A0MTS6_HUMAN" 5 1297.7473 1.86 64532 12485 2 1297.749208 649.8809 Methyl-CpG-binding domain protein 3 OS=Homo sapiens OX=9606 GN=MBD3 PE=1 SV=1 8.75 2401.9 - 510026 - - - 1.4664 - 1.955 0.456 - 243.2 1 2 0 0.0019 12 0 0 0 1.91E+07 1.03E+07 - - - 4.1723 0.9981 221125_WJC_METTL3_EV_vs_WT_F05.12490.12490.2 0.00303 24-Aug R.FSGSGSGTDFTLK.L "sp|A2NJV5|KV229_HUMAN,sp|A0A087WW87|KV240_HUMAN,sp|P06310|KV230_HUMAN,sp|A0A075B6S2|KVD29_HUMAN,sp|P01614|KVD40_HUMAN,sp|P01615|KVD28_HUMAN,sp|A0A075B6S6|KVD30_HUMAN,sp|A0A075B6P5|KV228_HUMAN,sp|A0A0A0MRZ7|KVD26_HUMAN" 9 1302.6092 21.22 64537 12490 2 1302.61244 652.3119 Immunoglobulin kappa variable 2-29 OS=Homo sapiens OX=9606 GN=IGKV2-29 PE=3 SV=2 5.84 2402.5 - 301307 - - - 2.4904 - 1.702 0.332 - 128.1 1 2 0 0.0032 13 0 0 0 1.23E+06 5.81E+04 - - - 2.857 1 221125_WJC_METTL3_EV_vs_WT_F05.12491.12491.2 1.75E-11 13/30 K.VQGSDSDEEVVVATTR.L "sp|P26640|SYVC_HUMAN,tr|A0A140T936|A0A140T936_HUMAN" 2 1690.801 0.65 64538 12491 2 1690.804328 846.4078 Valine--tRNA ligase OS=Homo sapiens OX=9606 GN=VARS1 PE=1 SV=4 3.92 2402.7 - 189629 - - - 1.9843 - 2.883 0.678 - 490.4 1 2 0 0.0034 16 0 0 0 2.91E+06 4.47E+06 - - - 6.6508 1 221125_WJC_METTL3_EV_vs_WT_F05.12493.12493.3 2.09E-06 13/48 R.YNIPHGPVVGSTR.R "sp|P50402|EMD_HUMAN,tr|A0A804HLA2|A0A804HLA2_HUMAN,tr|A0A804HIV7|A0A804HIV7_HUMAN" 3 1395.7259 1.3 64539 12493 3 1395.727155 466.2492 Emerin OS=Homo sapiens OX=9606 GN=EMD PE=1 SV=1 8.75 2402.9 - 1.47E+06 - - - 0.9006 - 2.376 0.5 - 157.9 1 2 0 0.0013 13 0 0 0 3.86E+07 2.97E+07 - - - 6.4606 0.9995 221125_WJC_METTL3_EV_vs_WT_F05.12498.12498.2 0.0106 26-Nov R.ILELSGSSSEDSEK[136.11].V sp|P78527|PRKDC_HUMAN 1 1487.7082 0.94 64543 12498 2 1487.709218 744.8614 DNA-dependent protein kinase catalytic subunit OS=Homo sapiens OX=9606 GN=PRKDC PE=1 SV=3 4 2403.3 - 1.20E+06 - - - 0.652 - 1.994 0.332 - 329.8 1 2 0 0.001 14 0 0 0 1.55E+07 1.66E+07 - - - 3.2247 1 221125_WJC_METTL3_EV_vs_WT_F05.12500.12500.3 3.12E-07 18/56 R.GISEETTTGVHNLYK[136.11].M sp|P23526|SAHH_HUMAN 1 1655.8246 0.96 64545 12500 3 1655.823465 552.9488 Adenosylhomocysteinase OS=Homo sapiens OX=9606 GN=AHCY PE=1 SV=4 5.4 2403.5 - 607500 - - - -0.6945 - 3.618 0.593 - 214.8 1 2 0 -0.0012 15 0 0 0 1.23E+07 1.27E+07 - - - 8.5065 0.9992 221125_WJC_METTL3_EV_vs_WT_F05.12502.12502.3 0.0112 Oct-40 R.TFSYTLEDHTK[136.11].Q "sp|Q14145|KEAP1_HUMAN,tr|K7ESE0|K7ESE0_HUMAN,tr|K7EJ49|K7EJ49_HUMAN,tr|K7EJD8|K7EJD8_HUMAN" 4 1348.639 0.97 64547 12502 3 1348.636904 450.5536 Kelch-like ECH-associated protein 1 OS=Homo sapiens OX=9606 GN=KEAP1 PE=1 SV=2 5.29 2403.8 - 268647 - - - -1.5883 - 1.6 0.341 - 133.9 1 2 0 -0.0021 11 0 0 0 2.83E+06 2.92E+06 - - - 3.6764 0.9982 221125_WJC_METTL3_EV_vs_WT_F05.12503.12503.3 0.00146 Aug-64 K.RPPAAPENTPLVPSGVK.S sp|P48634|PRC2A_HUMAN 1 1728.9523 1.51 64548 12503 3 1728.957297 577.3247 Protein PRRC2A OS=Homo sapiens OX=9606 GN=PRRC2A PE=1 SV=3 8.75 2403.9 - 239113 - - - 2.9081 - 1.682 0.357 - 76.6 1 2 0 0.005 17 0 0 0 2.57E+06 1.70E+06 - - - 3.8324 0.9997 221125_WJC_METTL3_EV_vs_WT_F05.12504.12504.2 0.000433 20-Aug R.SENSYQDAFSR.R sp|O15047|SET1A_HUMAN 1 1302.5477 1.32 64549 12504 2 1302.550063 652.2811 Histone-lysine N-methyltransferase SETD1A OS=Homo sapiens OX=9606 GN=SETD1A PE=1 SV=3 4.37 2404.1 - 355515 - - - 1.8456 - 1.813 0.515 - 224.4 1 2 0 0.0024 11 0 0 0 1.29E+06 9.80E+05 - - - 4.4536 0.9995 221125_WJC_METTL3_EV_vs_WT_F05.12508.12508.3 0.0265 14/44 K.TGNLGNVVHIER[166.11].F "sp|Q6P5R6|RL22L_HUMAN,tr|H0Y8C2|H0Y8C2_HUMAN,tr|C9JYQ9|C9JYQ9_HUMAN" 3 1317.7029 1.27 64553 12508 3 1317.709571 440.2416 60S ribosomal protein L22-like 1 OS=Homo sapiens OX=9606 GN=RPL22L1 PE=1 SV=2 6.41 2404.6 - 578730 - - - 5.0869 - 3.161 0.444 - 442.1 1 2 0 0.0067 12 0 0 0 1.92E+08 1.51E+08 - - - 6.6784 0.9996 221125_WJC_METTL3_EV_vs_WT_F05.12511.12511.2 0.000339 22-Sep R.ALEESNYELEGK.L "sp|P13645|K1C10_HUMAN,tr|A0A1B0GVI3|A0A1B0GVI3_HUMAN" 2 1380.6409 1109.79 64554 12511 2 1380.642796 691.3277 "Keratin, type I cytoskeletal 10 OS=Homo sapiens OX=9606 GN=KRT10 PE=1 SV=6" 4.09 2405 - 5.25E+06 - - - 1.3805 - 1.911 0.413 - 182.3 1 2 0 0.0019 12 0 0 0 8.54E+07 7.69E+04 - - - 3.7948 1 221125_WJC_METTL3_EV_vs_WT_F05.12512.12512.3 1.79E-06 16/44 K.TGNLGNVVHIER[166.11].F "sp|Q6P5R6|RL22L_HUMAN,tr|H0Y8C2|H0Y8C2_HUMAN,tr|C9JYQ9|C9JYQ9_HUMAN" 3 1317.7029 1.27 64555 12512 3 1317.703712 440.2416 60S ribosomal protein L22-like 1 OS=Homo sapiens OX=9606 GN=RPL22L1 PE=1 SV=2 6.41 2405 - 2.05E+06 - - - 0.6405 - 3.232 0.565 - 588 1 2 0 0.0008 12 0 0 0 1.92E+08 1.51E+08 - - - 8.0906 1 221125_WJC_METTL3_EV_vs_WT_F05.12514.12514.3 4.40E-06 15/56 R.GISEETTTGVHNLYK.M sp|P23526|SAHH_HUMAN 1 1647.8104 0.95 64557 12514 3 1647.812278 550.2774 Adenosylhomocysteinase OS=Homo sapiens OX=9606 GN=AHCY PE=1 SV=4 5.4 2405.2 - 1.03E+06 - - - 1.1306 - 3.031 0.581 - 136.5 1 2 0 0.0019 15 0 0 0 1.20E+07 1.27E+07 - - - 7.9106 0.9999 221125_WJC_METTL3_EV_vs_WT_F05.12519.12519.2 5.96E-06 18-Nov R.TEAESWYQTK.Y "sp|P13647|K2C5_HUMAN,tr|H0YI76|H0YI76_HUMAN,tr|H0YIN9|H0YIN9_HUMAN" 3 1241.5564 8.46 64562 12519 2 1241.55739 621.7855 "Keratin, type II cytoskeletal 5 OS=Homo sapiens OX=9606 GN=KRT5 PE=1 SV=3" 4.53 2405.9 - 329077 - - - 0.7716 - 2.075 0.571 - 476.5 1 2 0 0.001 10 0 0 0 2.51E+07 2.96E+06 - - - 5.2956 0.9997 221125_WJC_METTL3_EV_vs_WT_F05.12523.12523.2 7.39E-05 28-Jul K.ETLDPGDPETNNTIR.G "sp|Q86UA1|PRP39_HUMAN,tr|H0YJY9|H0YJY9_HUMAN" 2 1670.7748 1.7 64566 12523 2 1670.775555 836.3947 Pre-mRNA-processing factor 39 OS=Homo sapiens OX=9606 GN=PRPF39 PE=1 SV=3 3.92 2406.4 - 208774 - - - 0.477 - 1.665 0.486 - 90.8 1 2 0 0.0008 15 0 0 0 1.99E+06 1.17E+06 - - - 3.8838 0.775 221125_WJC_METTL3_EV_vs_WT_F05.12526.12526.2 0.563 24-Apr K.QATGRFEEDFIEK[136.11].R "sp|Q8WV41|SNX33_HUMAN,tr|H3BPR3|H3BPR3_HUMAN" 2 1576.7613 - 64569 12526 2 1576.763531 789.3879 Sorting nexin-33 OS=Homo sapiens OX=9606 GN=SNX33 PE=1 SV=1 4.41 2406.8 - 135850 - - - 1.4232 - 1.065 0.181 - 44.9 3 2 1 0.0022 13 0 0 0 - - - - - 0.3257 0.9754 221125_WJC_METTL3_EV_vs_WT_F05.12529.12529.3 0.287 Aug-40 R.NISHYEEQLVK.M "sp|P13861|KAP2_HUMAN,tr|H7C330|H7C330_HUMAN" 2 1358.683 1.78 64571 12529 3 1358.684953 453.9016 cAMP-dependent protein kinase type II-alpha regulatory subunit OS=Homo sapiens OX=9606 GN=PRKAR2A PE=1 SV=2 5.4 2407.3 - 340039 - - - 1.4153 - 1.282 0.198 - 62.4 1 2 0 0.0019 11 0 0 0 5.72E+07 3.21E+07 - - - 1.4527 1 221125_WJC_METTL3_EV_vs_WT_F05.12531.12531.3 3.19E-05 15/44 K.TGNLGNVVHIER.F "sp|Q6P5R6|RL22L_HUMAN,tr|H0Y8C2|H0Y8C2_HUMAN,tr|C9JYQ9|C9JYQ9_HUMAN" 3 1307.6946 1.27 64572 12531 3 1307.695534 436.9055 60S ribosomal protein L22-like 1 OS=Homo sapiens OX=9606 GN=RPL22L1 PE=1 SV=2 6.41 2407.5 - 9.56E+06 - - - 0.7158 - 3.114 0.491 - 515.8 1 2 0 0.0009 12 0 0 0 1.92E+08 1.51E+08 - - - 7.1625 0.9999 221125_WJC_METTL3_EV_vs_WT_F05.12532.12532.2 4.22E-05 13/24 K.ENINDEPVDMSAR.R "sp|Q8WXI9|P66B_HUMAN,tr|A0A0U1RR34|A0A0U1RR34_HUMAN,tr|A0A0U1RRM1|A0A0U1RRM1_HUMAN,tr|A0A0U1RRK3|A0A0U1RRK3_HUMAN" 4 1488.6515 1.75 64573 12532 2 1488.650786 745.333 Transcriptional repressor p66-beta OS=Homo sapiens OX=9606 GN=GATAD2B PE=1 SV=1 3.92 2407.5 - 2.79E+06 - - - -0.4608 - 2.557 0.577 - 587.8 1 2 0 -0.0007 13 0 0 0 2.80E+07 1.60E+07 - - - 5.7121 0.9999 221125_WJC_METTL3_EV_vs_WT_F05.12533.12533.2 1.78E-05 22-Dec R.AQVQEFC[160.03]DYGTK[136.11].E "sp|Q86U44|MTA70_HUMAN,tr|H0YFV6|H0YFV6_HUMAN" 2 1452.6435 0.01 64574 12533 2 1452.644888 727.329 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 4.37 2407.6 - 1.38E+06 - - - 0.9693 - 2.498 0.553 - 468.8 1 2 0 0.0014 12 0 0 0 2.22E+05 2.15E+07 - - - 5.5338 1 221125_WJC_METTL3_EV_vs_WT_F05.12540.12540.2 2.60E-09 14/22 K.TGNLGNVVHIER.F "sp|Q6P5R6|RL22L_HUMAN,tr|H0Y8C2|H0Y8C2_HUMAN,tr|C9JYQ9|C9JYQ9_HUMAN" 3 1307.6946 1.11 64581 12540 2 1307.700028 654.8546 60S ribosomal protein L22-like 1 OS=Homo sapiens OX=9606 GN=RPL22L1 PE=1 SV=2 6.41 2408.4 - 422399 - - - 4.1523 - 3.037 0.559 - 878.2 1 2 0 0.0054 12 0 0 0 1.19E+07 1.07E+07 - - - 6.091 0.9997 221125_WJC_METTL3_EV_vs_WT_F05.12542.12542.2 0.000211 13/26 K.LC[160.03]GTTQLDNEVPEK.V "sp|Q86UP3|ZFHX4_HUMAN,tr|E5RHS1|E5RHS1_HUMAN,tr|E5RGK3|E5RGK3_HUMAN,tr|E5RG79|E5RG79_HUMAN,tr|E5RI93|E5RI93_HUMAN,tr|E7EVZ1|E7EVZ1_HUMAN" 6 1602.7559 6.84 64583 12542 2 1602.75557 802.3852 Zinc finger homeobox protein 4 OS=Homo sapiens OX=9606 GN=ZFHX4 PE=1 SV=1 4.14 2408.7 - 393894 - - - -0.229 - 2.296 0.318 - 384 1 2 0 -0.0004 14 0 0 0 5.04E+06 7.37E+05 - - - 3.4754 0.9854 221125_WJC_METTL3_EV_vs_WT_F05.12543.12543.3 0.251 Sep-36 K.QQQELHLALK.Q sp|Q96EU6|RRP36_HUMAN 1 1206.6721 4.34 64584 12543 3 1206.672563 403.2313 Ribosomal RNA processing protein 36 homolog OS=Homo sapiens OX=9606 GN=RRP36 PE=1 SV=1 6.75 2408.8 - 376255 - - - 0.4077 - 1.525 0.162 - 125.7 1 2 0 0.0005 10 0 0 0 1.19E+07 2.75E+06 - - - 1.5784 0.9986 221125_WJC_METTL3_EV_vs_WT_F05.12544.12544.3 0.0411 Nov-44 R.SKGAVAIADAIR.G "sp|P46060|RAGP1_HUMAN,tr|H0Y4Q3|H0Y4Q3_HUMAN" 2 1170.6721 1.46 64585 12544 3 1170.672762 391.2313 Ran GTPase-activating protein 1 OS=Homo sapiens OX=9606 GN=RANGAP1 PE=1 SV=1 8.46 2409 - 313696 - - - 0.5903 - 2.083 0.328 - 127.1 1 2 1 0.0007 12 0 0 0 3.83E+06 2.62E+06 - - - 4.2307 0.9999 221125_WJC_METTL3_EV_vs_WT_F05.12547.12547.3 2.19E-05 Nov-48 R.SLQEEHVAVAQLR[166.11].E sp|Q15149|PLEC_HUMAN 1 1488.7924 2.1 64588 12547 3 1488.792632 497.2714 Plectin OS=Homo sapiens OX=9606 GN=PLEC PE=1 SV=3 5.38 2409.4 - 286434 - - - 0.1484 - 1.977 0.476 - 119.5 1 2 0 0.0002 13 0 0 0 3.64E+06 1.74E+06 - - - 5.6948 1 221125_WJC_METTL3_EV_vs_WT_F05.12550.12550.2 3.23E-07 24-Dec K.C[160.03]LDENLEDASQC[160.03]K[136.11].K sp|Q5JTJ3|COA6_HUMAN 1 1588.6589 1.13 64591 12550 2 1588.661635 795.3367 Cytochrome c oxidase assembly factor 6 homolog OS=Homo sapiens OX=9606 GN=COA6 PE=1 SV=1 3.92 2409.7 - 152664 - - - 1.7392 - 2.714 0.696 - 356.4 1 2 0 0.0028 13 0 0 0 1.30E+06 1.15E+06 - - - 6.7433 1 221125_WJC_METTL3_EV_vs_WT_F05.12554.12554.2 2.69E-07 24-Dec K.ENINDEPVDMSAR[166.11].R "sp|Q8WXI9|P66B_HUMAN,tr|A0A0U1RR34|A0A0U1RR34_HUMAN,tr|A0A0U1RRM1|A0A0U1RRM1_HUMAN,tr|A0A0U1RRK3|A0A0U1RRK3_HUMAN" 4 1498.6597 1.75 64594 12554 2 1498.658499 750.3371 Transcriptional repressor p66-beta OS=Homo sapiens OX=9606 GN=GATAD2B PE=1 SV=1 3.92 2410.2 - 1.52E+06 - - - -0.8294 - 2.517 0.63 - 493.3 1 2 0 -0.0012 13 0 0 0 2.80E+07 1.60E+07 - - - 6.0629 0.9998 221125_WJC_METTL3_EV_vs_WT_F05.12556.12556.3 0.00366 Oct-44 R.GSAVHQLSEELR.C "sp|P58107|EPIPL_HUMAN,sp|P58107|EPIPL_HUMAN,sp|P58107|EPIPL_HUMAN,sp|P58107|EPIPL_HUMAN,sp|P58107|EPIPL_HUMAN,tr|A0A075B730|A0A075B730_HUMAN,tr|A0A075B730|A0A075B730_HUMAN,tr|A0A075B730|A0A075B730_HUMAN,tr|A0A075B730|A0A075B730_HUMAN,tr|A0A075B730|A0A075B730_HUMAN" 10 1324.6735 1.04 64596 12556 3 1324.674074 442.5651 Epiplakin OS=Homo sapiens OX=9606 GN=EPPK1 PE=1 SV=3 5.4 2410.4 - 604882 - - - 0.4122 - 2.027 0.36 - 160.8 1 2 0 0.0005 12 0 0 0 1.12E+07 1.08E+07 - - - 4.512 1 221125_WJC_METTL3_EV_vs_WT_F05.12557.12557.2 6.69E-08 13/26 K.QGTPEYSLETSAGR[166.11].E sp|P17482|HXB9_HUMAN 1 1504.7033 0.99 64597 12557 2 1504.706759 753.3589 Homeobox protein Hox-B9 OS=Homo sapiens OX=9606 GN=HOXB9 PE=1 SV=2 4.53 2410.5 - 480957 - - - 2.2848 - 2.582 0.596 - 647.9 1 2 0 0.0034 14 0 0 0 7.80E+06 7.91E+06 - - - 5.8224 0.9998 221125_WJC_METTL3_EV_vs_WT_F05.12559.12559.2 0.000466 22-Oct K.KPSISITTESLK.S "sp|Q9UKV3|ACINU_HUMAN,tr|G3V3B0|G3V3B0_HUMAN,tr|S4R3H4|S4R3H4_HUMAN,tr|E7EQT4|E7EQT4_HUMAN,tr|G3V3T3|G3V3T3_HUMAN" 5 1302.7395 1.45 64599 12559 2 1302.740569 652.377 Apoptotic chromatin condensation inducer in the nucleus OS=Homo sapiens OX=9606 GN=ACIN1 PE=1 SV=2 8.59 2410.8 - 343897 - - - 0.8344 - 2.242 0.401 - 259.5 1 2 0 0.0011 12 0 0 0 2.20E+06 1.52E+06 - - - 4.1268 0.9985 221125_WJC_METTL3_EV_vs_WT_F05.12561.12561.2 0.0003 16-Aug R.EEQFNSTFR.V "sp|P01859|IGHG2_HUMAN,tr|A0A286YEY4|A0A286YEY4_HUMAN" 2 1156.5149 8.34 64601 12561 2 1156.511175 579.2647 Immunoglobulin heavy constant gamma 2 OS=Homo sapiens OX=9606 GN=IGHG2 PE=1 SV=2 4.53 2411 - 289457 - - - -3.2226 - 1.514 0.464 - 302.8 1 2 0 -0.0037 9 0 0 0 4.00E+06 4.79E+05 - - - 3.6668 0.9999 221125_WJC_METTL3_EV_vs_WT_F05.12563.12563.2 6.97E-07 24-Nov K.GEDQSELVTTVDK.V "sp|Q8NC56|LEMD2_HUMAN,tr|D6R958|D6R958_HUMAN,tr|H7C2Z0|H7C2Z0_HUMAN" 3 1419.6729 5.25 64603 12563 2 1419.6738 710.8437 LEM domain-containing protein 2 OS=Homo sapiens OX=9606 GN=LEMD2 PE=1 SV=1 3.92 2411.3 - 247551 - - - 0.6206 - 2.394 0.548 - 628.5 1 2 0 0.0009 13 0 0 0 1.13E+06 2.16E+05 - - - 5.3287 0.9971 221125_WJC_METTL3_EV_vs_WT_F05.12569.12569.3 0.0215 Oct-52 R.SLDPADER[166.11]DDVLAK[136.11].R "sp|Q8WXI9|P66B_HUMAN,tr|A0A0U1RR34|A0A0U1RR34_HUMAN,tr|A0A0U1RRM1|A0A0U1RRM1_HUMAN,tr|A0A0U1RRK3|A0A0U1RRK3_HUMAN" 4 1560.775 2.34 64607 12569 3 1560.773829 521.2656 Transcriptional repressor p66-beta OS=Homo sapiens OX=9606 GN=GATAD2B PE=1 SV=1 4.04 2412.1 - 8.25E+06 - - - -0.7733 - 1.561 0.352 - 80.3 1 2 1 -0.0012 14 0 0 0 1.79E+08 7.66E+07 - - - 3.6476 0.9983 221125_WJC_METTL3_EV_vs_WT_F05.12572.12572.2 0.0414 14/26 R.SLDPADERDDVLAK.R "sp|Q8WXI9|P66B_HUMAN,tr|A0A0U1RR34|A0A0U1RR34_HUMAN,tr|A0A0U1RRM1|A0A0U1RRM1_HUMAN,tr|A0A0U1RRK3|A0A0U1RRK3_HUMAN" 4 1542.7526 2.4 64610 12572 2 1542.750877 772.3836 Transcriptional repressor p66-beta OS=Homo sapiens OX=9606 GN=GATAD2B PE=1 SV=1 4.04 2412.3 - 1.05E+06 - - - -1.0948 - 2.934 0.419 - 441.2 1 2 1 -0.0017 14 0 0 0 1.43E+07 5.96E+06 - - - 4.8363 1 221125_WJC_METTL3_EV_vs_WT_F05.12575.12575.2 5.66E-08 14/26 K.IQVLQQQADDAEER[166.11].A "tr|Q5VU61|Q5VU61_HUMAN,tr|A0A087WWU8|A0A087WWU8_HUMAN,tr|D6R904|D6R904_HUMAN" 3 1651.8041 0.99 64613 12575 2 1651.802155 826.9093 Tropomyosin alpha-3 chain OS=Homo sapiens OX=9606 GN=TPM3 PE=1 SV=3 3.92 2412.7 - 685559 - - - -1.1763 - 2.912 0.57 - 569.7 1 2 0 -0.0019 14 0 0 0 2.02E+07 2.04E+07 - - - 5.9326 0.9971 221125_WJC_METTL3_EV_vs_WT_F05.12576.12576.3 0.00031 Nov-52 K.LEPQIASASEYAHR[166.11].G "sp|O60664|PLIN3_HUMAN,tr|K7EL96|K7EL96_HUMAN,tr|K7ER39|K7ER39_HUMAN" 3 1580.7822 2.16 64614 12576 3 1580.772031 527.9347 Perilipin-3 OS=Homo sapiens OX=9606 GN=PLIN3 PE=1 SV=3 5.4 2412.8 - 646867 - - - -6.4582 - 2.141 0.452 - 134 1 2 0 -0.0102 14 0 0 0 1.29E+07 5.97E+06 - - - 5.5996 0.9999 221125_WJC_METTL3_EV_vs_WT_F05.12577.12577.2 1.76E-07 14/26 K.IQVLQQQADDAEER.A "tr|Q5VU61|Q5VU61_HUMAN,tr|A0A087WWU8|A0A087WWU8_HUMAN,tr|D6R904|D6R904_HUMAN" 3 1641.7958 0.99 64615 12577 2 1641.795042 821.9052 Tropomyosin alpha-3 chain OS=Homo sapiens OX=9606 GN=TPM3 PE=1 SV=3 3.92 2412.9 - 578924 - - - -0.4787 - 2.897 0.52 - 568.7 1 2 0 -0.0008 14 0 0 0 2.02E+07 2.04E+07 - - - 5.5507 1 221125_WJC_METTL3_EV_vs_WT_F05.12578.12578.2 9.24E-05 14/32 R.TPAPEPEPC[160.03]EASELPAK.R "sp|Q9ULV3|CIZ1_HUMAN,tr|Q5SYW2|Q5SYW2_HUMAN,tr|F5H2X7|F5H2X7_HUMAN,tr|H0Y5D5|H0Y5D5_HUMAN,tr|A0A494C0L7|A0A494C0L7_HUMAN,tr|Q9BTG3|Q9BTG3_HUMAN" 6 1821.8455 3.99 64616 12578 2 1821.846353 911.93 Cip1-interacting zinc finger protein OS=Homo sapiens OX=9606 GN=CIZ1 PE=1 SV=2 4.09 2413 - 503782 - - - 0.4786 - 2.935 0.611 - 423.1 1 2 0 0.0009 17 0 0 0 1.01E+07 2.52E+06 - - - 6.2007 1 221125_WJC_METTL3_EV_vs_WT_F05.12580.12580.2 4.00E-11 15/28 R.SC[160.03]MLTGTPESVQSAK.R "sp|Q96AE4|FUBP1_HUMAN,tr|E9PEB5|E9PEB5_HUMAN,tr|C9JSZ1|C9JSZ1_HUMAN" 3 1594.7331 0.44 64618 12580 2 1594.732225 798.3738 Far upstream element-binding protein 1 OS=Homo sapiens OX=9606 GN=FUBP1 PE=1 SV=3 5.72 2413.3 - 417077 - - - -0.5443 - 2.865 0.773 - 630.9 1 2 0 -0.0009 15 0 0 0 2.62E+06 5.94E+06 - - - 7.3379 0.8263 221125_WJC_METTL3_EV_vs_WT_F05.12581.12581.3 0.0714 Oct-52 K.VEESPLEK[136.11]VETPPK[136.11].A "sp|Q8IWC1|MA7D3_HUMAN,tr|A0A0A0MRP0|A0A0A0MRP0_HUMAN" 2 1596.8582 0.81 64619 12581 3 1596.853096 533.2933 MAP7 domain-containing protein 3 OS=Homo sapiens OX=9606 GN=MAP7D3 PE=1 SV=2 4.49 2413.4 - 372374 - - - -3.1675 - 1.577 0.181 - 95.9 1 2 1 -0.0051 14 0 0 0 1.90E+06 2.34E+06 - - - 1.7671 0.9997 221125_WJC_METTL3_EV_vs_WT_F05.12582.12582.4 0.000502 Dec-72 R.LIHEDGIIRPYDR.Q "sp|Q709C8|VP13C_HUMAN,tr|A0A3B3IU50|A0A3B3IU50_HUMAN" 2 1595.842 0.55 64620 12582 4 1595.840045 399.9678 Vacuolar protein sorting-associated protein 13C OS=Homo sapiens OX=9606 GN=VPS13C PE=1 SV=1 5.38 2413.6 - 324202 - - - -1.2188 - 2.375 0.347 - 174.6 1 2 0 -0.0019 13 0 0 0 2.18E+06 3.97E+06 - - - 2.5665 0.993 221125_WJC_METTL3_EV_vs_WT_F05.12583.12583.2 8.71E-06 18-Nov G.NLGNVVHIER.F "sp|Q6P5R6|RL22L_HUMAN,tr|H0Y8C2|H0Y8C2_HUMAN,tr|C9JYQ9|C9JYQ9_HUMAN" 3 1149.6255 1.15 64621 12583 2 1149.625027 575.82 60S ribosomal protein L22-like 1 OS=Homo sapiens OX=9606 GN=RPL22L1 PE=1 SV=2 6.75 2413.7 - 264835 - - - -0.3723 - 2.269 0.486 - 523.8 1 1 0 -0.0004 10 0 0 0 1.68E+06 1.46E+06 - - - 4.9175 0.9997 221125_WJC_METTL3_EV_vs_WT_F05.12585.12585.2 4.13E-06 28-Aug R.LGLHQQGSEPSYLDR.T "sp|Q9BV38|WDR18_HUMAN,tr|U3KQC1|U3KQC1_HUMAN,tr|A0A0A0MQU0|A0A0A0MQU0_HUMAN" 3 1698.8325 0.84 64623 12585 2 1698.82908 850.4236 WD repeat-containing protein 18 OS=Homo sapiens OX=9606 GN=WDR18 PE=1 SV=2 5.32 2413.9 - 235539 - - - -2.0414 - 1.871 0.551 - 162.7 1 2 0 -0.0035 15 0 0 0 1.99E+06 2.37E+06 - - - 4.6498 0.9906 221125_WJC_METTL3_EV_vs_WT_F05.12589.12589.3 0.0246 Nov-44 R.SK[136.11]GAVAIADAIR[166.11].G "sp|P46060|RAGP1_HUMAN,tr|H0Y4Q3|H0Y4Q3_HUMAN" 2 1188.6945 1.48 64626 12589 3 1188.693733 397.2388 Ran GTPase-activating protein 1 OS=Homo sapiens OX=9606 GN=RANGAP1 PE=1 SV=1 8.46 2414.4 - 561829 - - - -0.6797 - 1.682 0.254 - 110.7 1 2 1 -0.0008 12 0 0 0 3.83E+06 2.59E+06 - - - 2.8129 1 221125_WJC_METTL3_EV_vs_WT_F05.12590.12590.3 0.00591 19/60 K.VIAQQVQLQQQQEQVR.L sp|Q01664|TFAP4_HUMAN 1 1922.0334 1.93 64627 12590 3 1922.033685 641.6851 Transcription factor AP-4 OS=Homo sapiens OX=9606 GN=TFAP4 PE=1 SV=2 5.97 2414.5 - 2.05E+06 - - - 0.1623 - 3.548 0.528 - 594.3 1 2 0 0.0003 16 0 0 0 5.63E+07 2.93E+07 - - - 7.676 1 221125_WJC_METTL3_EV_vs_WT_F05.12591.12591.3 3.73E-06 13/40 R.SDEAVK[136.11]PFGLK[136.11].V "sp|P49327|FAS_HUMAN,tr|A0A0U1RQF0|A0A0U1RQF0_HUMAN" 2 1205.6627 0.65 64628 12591 3 1205.660722 402.8948 Fatty acid synthase OS=Homo sapiens OX=9606 GN=FASN PE=1 SV=3 5.79 2414.6 - 1.32E+06 - - - -1.6315 - 2.366 0.541 - 198.7 1 2 0 -0.002 11 0 0 0 9.80E+06 1.50E+07 - - - 7.0176 0.9998 221125_WJC_METTL3_EV_vs_WT_F05.12592.12592.2 1.13E-05 26-Nov K.QGTPEYSLETSAGR.E sp|P17482|HXB9_HUMAN 1 1494.6951 0.99 64629 12592 2 1494.696616 748.3548 Homeobox protein Hox-B9 OS=Homo sapiens OX=9606 GN=HOXB9 PE=1 SV=2 4.53 2414.6 - 1.28E+06 - - - 1.047 - 2.094 0.535 - 277.1 1 2 0 0.0016 14 0 0 0 7.80E+06 7.91E+06 - - - 4.8467 0.9975 221125_WJC_METTL3_EV_vs_WT_F05.12593.12593.3 0.0274 Nov-44 K.LKQSLPPGLAVK.E sp|P63173|RL38_HUMAN 1 1249.7758 1.1 64630 12593 3 1249.774564 417.5992 60S ribosomal protein L38 OS=Homo sapiens OX=9606 GN=RPL38 PE=1 SV=2 10 2414.7 - 1.08E+06 - - - -0.9954 - 1.887 0.311 - 221.5 1 2 1 -0.0012 12 0 0 0 1.54E+07 1.40E+07 - - - 3.7671 0.9845 221125_WJC_METTL3_EV_vs_WT_F05.12594.12594.3 1.24 Dec-44 K.LK[136.11]QSLPPGLAVK[136.11].E sp|P63173|RL38_HUMAN 1 1265.8042 1.1 64631 12594 3 1265.803121 422.942 60S ribosomal protein L38 OS=Homo sapiens OX=9606 GN=RPL38 PE=1 SV=2 10 2414.9 - 1.07E+06 - - - -0.8587 - 2.185 0.159 - 245.5 1 2 1 -0.0011 12 0 0 0 1.54E+07 1.40E+07 - - - 2.4789 0.9998 221125_WJC_METTL3_EV_vs_WT_F05.12595.12595.3 8.25E-05 15/52 M.GLVC[160.03]VLGDGK[136.11]TEQK[136.11].G tr|Q5RI18|Q5RI18_HUMAN 1 1518.8047 1.22 64632 12595 3 1518.807424 507.2755 Heterogeneous nuclear ribonucleoprotein U OS=Homo sapiens OX=9606 GN=HNRNPU PE=1 SV=9 6.06 2415 - 893246 - - - 1.8073 - 2.872 0.489 - 259.8 1 2 1 0.0027 14 0 0 0 6.71E+06 5.51E+06 - - - 6.7948 0.9999 221125_WJC_METTL3_EV_vs_WT_F05.12596.12596.3 1.01E-06 14/52 K.IQVLQQQADDAEER[166.11].A "tr|Q5VU61|Q5VU61_HUMAN,tr|A0A087WWU8|A0A087WWU8_HUMAN,tr|D6R904|D6R904_HUMAN" 3 1651.8041 0.92 64633 12596 3 1651.799541 551.6086 Tropomyosin alpha-3 chain OS=Homo sapiens OX=9606 GN=TPM3 PE=1 SV=3 3.92 2415.1 - 846633 - - - -2.7588 - 2.702 0.552 - 313 1 2 0 -0.0046 14 0 0 0 7.36E+06 8.04E+06 - - - 7.3346 1 221125_WJC_METTL3_EV_vs_WT_F05.12598.12598.3 4.68E-05 15/52 K.IQVLQQQADDAEER.A "tr|Q5VU61|Q5VU61_HUMAN,tr|A0A087WWU8|A0A087WWU8_HUMAN,tr|D6R904|D6R904_HUMAN" 3 1641.7958 0.92 64635 12598 3 1641.797909 548.2726 Tropomyosin alpha-3 chain OS=Homo sapiens OX=9606 GN=TPM3 PE=1 SV=3 3.92 2415.3 - 638298 - - - 1.2675 - 2.634 0.48 - 315.5 1 2 0 0.0021 14 0 0 0 7.25E+06 7.84E+06 - - - 6.4648 0.93 221125_WJC_METTL3_EV_vs_WT_F05.12599.12599.2 0.000972 15/22 L.DPADERDDVLAK.R "sp|Q8WXI9|P66B_HUMAN,tr|A0A0U1RR34|A0A0U1RR34_HUMAN,tr|A0A0U1RRM1|A0A0U1RRM1_HUMAN,tr|A0A0U1RRK3|A0A0U1RRK3_HUMAN" 4 1342.6365 1.84 64636 12599 2 1342.637673 672.3255 Transcriptional repressor p66-beta OS=Homo sapiens OX=9606 GN=GATAD2B PE=1 SV=1 4.04 2415.4 - 616192 - - - 0.893 - 2.934 0.491 - 615 1 1 1 0.0012 12 0 0 0 7.28E+06 3.96E+06 - - - 5.4993 1 221125_WJC_METTL3_EV_vs_WT_F05.12600.12600.3 1.09E-07 16/40 R.SDEAVKPFGLK.V "sp|P49327|FAS_HUMAN,tr|A0A0U1RQF0|A0A0U1RQF0_HUMAN" 2 1189.6343 0.66 64637 12600 3 1189.633816 397.552 Fatty acid synthase OS=Homo sapiens OX=9606 GN=FASN PE=1 SV=3 5.79 2415.5 - 561829 - - - -0.3976 - 2.816 0.542 - 328.1 1 2 0 -0.0005 11 0 0 0 9.80E+06 1.48E+07 - - - 7.5238 0.9988 221125_WJC_METTL3_EV_vs_WT_F05.12601.12601.4 0.00958 Nov-72 R.LIHEDGIIR[166.11]PYDR[166.11].Q "sp|Q709C8|VP13C_HUMAN,tr|A0A3B3IU50|A0A3B3IU50_HUMAN" 2 1615.8585 0.55 64638 12601 4 1615.854712 404.9719 Vacuolar protein sorting-associated protein 13C OS=Homo sapiens OX=9606 GN=VPS13C PE=1 SV=1 5.38 2415.6 - 521364 - - - -2.3628 - 1.821 0.324 - 136.7 1 2 0 -0.0038 13 0 0 0 2.18E+06 3.97E+06 - - - 2.2673 0.8961 221125_WJC_METTL3_EV_vs_WT_F05.12602.12602.2 3.67 20-Sep N.KDNENLYITIK.L "sp|Q13315|ATM_HUMAN,tr|A0A6Q8PH76|A0A6Q8PH76_HUMAN" 2 1349.7191 999 64639 12602 2 1349.718063 675.8668 Serine-protein kinase ATM OS=Homo sapiens OX=9606 GN=ATM PE=1 SV=4 6.07 2415.8 - 516942 - - - -0.7542 - 1.631 0.207 - 221.3 1 1 0 -0.001 11 0 0 0 4.52E+07 0.00E+00 - - - 1.893 1 221125_WJC_METTL3_EV_vs_WT_F05.12604.12604.2 7.34E-09 14/24 K.ITESVAETAQTIK.K sp|Q96A49|SYAP1_HUMAN 1 1389.7351 1.36 64641 12604 2 1389.735041 695.8748 Synapse-associated protein 1 OS=Homo sapiens OX=9606 GN=SYAP1 PE=1 SV=1 4.53 2416 - 366410 - - - -0.0604 - 2.941 0.571 - 784.1 1 2 0 -0.0001 13 0 0 0 1.64E+07 1.20E+07 - - - 6.027 0.9998 221125_WJC_METTL3_EV_vs_WT_F05.12605.12605.2 0.0012 13/24 K.ITESVAETAQTIK[136.11].K sp|Q96A49|SYAP1_HUMAN 1 1397.7493 1.35 64642 12605 2 1397.748123 699.8819 Synapse-associated protein 1 OS=Homo sapiens OX=9606 GN=SYAP1 PE=1 SV=1 4.53 2416.2 - 306241 - - - -0.86 - 2.706 0.413 - 550.8 1 2 0 -0.0012 13 0 0 0 1.60E+07 1.19E+07 - - - 4.6459 0.9983 221125_WJC_METTL3_EV_vs_WT_F05.12609.12609.3 0.0117 13/52 K.TVSPDRLELEAAQK.F "sp|Q14974|IMB1_HUMAN,tr|J3QR48|J3QR48_HUMAN" 2 1555.8206 1.3 64644 12609 3 1555.820271 519.6141 Importin subunit beta-1 OS=Homo sapiens OX=9606 GN=KPNB1 PE=1 SV=2 4.68 2416.7 - 1.20E+07 - - - -0.2025 - 2.193 0.308 - 124.7 1 2 1 -0.0003 14 0 0 0 1.43E+08 1.10E+08 - - - 4.0607 1 221125_WJC_METTL3_EV_vs_WT_F05.12611.12611.3 5.64E-08 17/56 R.TPVIDADK[136.11]PVSSQLR[166.11].V "sp|Q14204|DYHC1_HUMAN,tr|A0A7P0T8N2|A0A7P0T8N2_HUMAN,tr|A0A7P0T9C4|A0A7P0T9C4_HUMAN,tr|A0A7P0TBJ7|A0A7P0TBJ7_HUMAN,tr|A0A804HHY6|A0A804HHY6_HUMAN,tr|A0A7P0T9K2|A0A7P0T9K2_HUMAN,tr|A0A7P0TB64|A0A7P0TB64_HUMAN,tr|A0A2R8Y706|A0A2R8Y706_HUMAN,tr|A0A7P0T916|A0A7P0T916_HUMAN,tr|A0A7P0TB75|A0A7P0TB75_HUMAN,tr|A0A7P0T8W5|A0A7P0T8W5_HUMAN,tr|A0A7P0T9S3|A0A7P0T9S3_HUMAN,tr|A0A7P0TAF3|A0A7P0TAF3_HUMAN,tr|A0A7P0T9F1|A0A7P0T9F1_HUMAN,tr|A0A7P0TAW9|A0A7P0TAW9_HUMAN,tr|A0A2R8YGC7|A0A2R8YGC7_HUMAN,tr|A0A7P0TA13|A0A7P0TA13_HUMAN,tr|A0A7P0T934|A0A7P0T934_HUMAN,tr|A0A7P0TAV5|A0A7P0TAV5_HUMAN,tr|A0A7P0T9Y3|A0A7P0T9Y3_HUMAN,tr|A0A7P0T7V5|A0A7P0T7V5_HUMAN,tr|A0A7P0T9R4|A0A7P0T9R4_HUMAN,tr|A0A2R8Y5T0|A0A2R8Y5T0_HUMAN,tr|A0A7P0T990|A0A7P0T990_HUMAN,tr|A0A7P0T942|A0A7P0T942_HUMAN,tr|A0A7P0TAS7|A0A7P0TAS7_HUMAN,tr|A0A2R8YFZ7|A0A2R8YFZ7_HUMAN,tr|A0A7P0T825|A0A7P0T825_HUMAN,tr|A0A2R8Y6H2|A0A2R8Y6H2_HUMAN,tr|A0A7P0TBC9|A0A7P0TBC9_HUMAN,tr|A0A7P0TAM4|A0A7P0TAM4_HUMAN" 31 1642.9009 0.91 64646 12611 3 1642.900017 548.6409 Cytoplasmic dynein 1 heavy chain 1 OS=Homo sapiens OX=9606 GN=DYNC1H1 PE=1 SV=5 5.63 2416.8 - 2.55E+06 - - - -0.5405 - 3.455 0.577 - 336.4 1 2 0 -0.0009 15 0 0 0 2.12E+07 2.32E+07 - - - 8.2079 1 221125_WJC_METTL3_EV_vs_WT_F05.12612.12612.3 0.000127 18/52 R.IQALAEETAQNLK[136.11]R[166.11].N sp|Q8IYI6|EXOC8_HUMAN 1 1601.8856 1.87 64647 12612 3 1601.885053 534.9691 Exocyst complex component 8 OS=Homo sapiens OX=9606 GN=EXOC8 PE=1 SV=2 6.14 2416.9 - 1.13E+06 - - - -0.3352 - 3.824 0.503 - 554.9 1 2 0 -0.0005 14 0 0 0 4.73E+07 2.53E+07 - - - 7.7123 1 221125_WJC_METTL3_EV_vs_WT_F05.12613.12613.2 0.000349 19/30 K.VIAQQVQLQQQQEQVR.L sp|Q01664|TFAP4_HUMAN 1 1922.0334 2.35 64648 12613 2 1922.033874 962.024 Transcription factor AP-4 OS=Homo sapiens OX=9606 GN=TFAP4 PE=1 SV=2 5.97 2417 - 783468 - - - 0.2607 - 4.081 0.605 - 1538.3 1 2 0 0.0005 16 0 0 0 8.69E+06 3.69E+06 - - - 6.9669 0.9994 221125_WJC_METTL3_EV_vs_WT_F05.12614.12614.3 0.00179 Sep-44 R.GSAVHQLSEELR[166.11].C "sp|P58107|EPIPL_HUMAN,sp|P58107|EPIPL_HUMAN,sp|P58107|EPIPL_HUMAN,sp|P58107|EPIPL_HUMAN,sp|P58107|EPIPL_HUMAN,tr|A0A075B730|A0A075B730_HUMAN,tr|A0A075B730|A0A075B730_HUMAN,tr|A0A075B730|A0A075B730_HUMAN,tr|A0A075B730|A0A075B730_HUMAN,tr|A0A075B730|A0A075B730_HUMAN" 10 1334.6818 1.36 64649 12614 3 1334.679971 445.9012 Epiplakin OS=Homo sapiens OX=9606 GN=EPPK1 PE=1 SV=3 5.4 2417.1 - 778548 - - - -1.3689 - 1.938 0.304 - 115.5 1 2 0 -0.0018 12 0 0 0 1.52E+07 1.12E+07 - - - 3.7628 0.9998 221125_WJC_METTL3_EV_vs_WT_F05.12618.12618.2 0.000103 22-Oct K.YQVPC[160.03]QTQTYVK.C sp|Q5T750|XP32_HUMAN 1 1513.7235 58.77 64653 12618 2 1513.724196 757.869 Skin-specific protein 32 OS=Homo sapiens OX=9606 GN=XP32 PE=1 SV=1 8.18 2417.6 - 331455 - - - 0.4499 - 1.642 0.544 - 184.9 1 2 0 0.0007 12 0 0 0 2.99E+07 5.09E+05 - - - 4.3636 0.9998 221125_WJC_METTL3_EV_vs_WT_F05.12619.12619.2 1.90E-06 Sep-32 R.TPAPEPEPC[160.03]EASELPAK[136.11].R "sp|Q9ULV3|CIZ1_HUMAN,tr|Q5SYW2|Q5SYW2_HUMAN,tr|F5H2X7|F5H2X7_HUMAN,tr|H0Y5D5|H0Y5D5_HUMAN,tr|A0A494C0L7|A0A494C0L7_HUMAN,tr|Q9BTG3|Q9BTG3_HUMAN" 6 1829.8597 3.99 64654 12619 2 1829.862035 915.9371 Cip1-interacting zinc finger protein OS=Homo sapiens OX=9606 GN=CIZ1 PE=1 SV=2 4.09 2417.8 - 294882 - - - 1.2864 - 2.029 0.556 - 202.7 1 2 0 0.0024 17 0 0 0 1.01E+07 2.52E+06 - - - 4.8864 0.9979 221125_WJC_METTL3_EV_vs_WT_F05.12620.12620.2 0.00964 18-Aug K.EQNSPIYISR.L "sp|O14910|LIN7A_HUMAN,sp|Q9NUP9|LIN7C_HUMAN,sp|Q9HAP6|LIN7B_HUMAN,tr|H0YIA8|H0YIA8_HUMAN,tr|G3V1D4|G3V1D4_HUMAN,tr|H0YI92|H0YI92_HUMAN" 6 1205.6041 1.73 64655 12620 2 1205.601878 603.8093 Protein lin-7 homolog A OS=Homo sapiens OX=9606 GN=LIN7A PE=1 SV=2 6.1 2417.9 - 222482 - - - -1.8024 - 1.317 0.331 - 212 1 2 0 -0.0022 10 0 0 0 3.56E+06 2.06E+06 - - - 2.2537 0.9998 221125_WJC_METTL3_EV_vs_WT_F05.12621.12621.2 2.35E-05 20-Sep R.SDEAVKPFGLK.V "sp|P49327|FAS_HUMAN,tr|A0A0U1RQF0|A0A0U1RQF0_HUMAN" 2 1189.6343 0.98 64656 12621 2 1189.635947 595.8244 Fatty acid synthase OS=Homo sapiens OX=9606 GN=FASN PE=1 SV=3 5.79 2418 - 202547 - - - 1.3937 - 1.947 0.505 - 230.3 1 2 0 0.0017 11 0 0 0 1.45E+06 1.49E+06 - - - 4.5729 1 221125_WJC_METTL3_EV_vs_WT_F05.12624.12624.2 6.76E-08 24-Dec K.DMYNDTLNGSTEK.R sp|Q96PU8|QKI_HUMAN 1 1486.6246 2.61 64658 12624 2 1486.62359 744.3196 Protein quaking OS=Homo sapiens OX=9606 GN=QKI PE=1 SV=1 4.03 2418.4 - 4.54E+06 - - - -0.6713 - 2.563 0.661 - 379.6 1 2 0 -0.001 13 0 0 0 4.06E+07 1.56E+07 - - - 6.3384 1 221125_WJC_METTL3_EV_vs_WT_F05.12626.12626.3 0.001 18/52 R.IQALAEETAQNLKR.N sp|Q8IYI6|EXOC8_HUMAN 1 1583.8631 1.87 64659 12626 3 1583.861505 528.9616 Exocyst complex component 8 OS=Homo sapiens OX=9606 GN=EXOC8 PE=1 SV=2 6.14 2418.6 - 3.54E+06 - - - -1.0197 - 3.421 0.433 - 657.4 1 2 0 -0.0016 14 0 0 0 4.73E+07 2.53E+07 - - - 6.6357 0.9987 221125_WJC_METTL3_EV_vs_WT_F05.12627.12627.3 0.000855 15/44 K.GK[136.11]VEEVELPVEK[136.11].V "sp|Q99873|ANM1_HUMAN,sp|Q9NR22|ANM8_HUMAN,tr|E9PQ98|E9PQ98_HUMAN,tr|E9PKG1|E9PKG1_HUMAN,tr|E9PNR9|E9PNR9_HUMAN,tr|H0YDE4|H0YDE4_HUMAN,tr|E9PIX6|E9PIX6_HUMAN" 7 1370.7628 2.18 64660 12627 3 1370.761077 457.9282 Protein arginine N-methyltransferase 1 OS=Homo sapiens OX=9606 GN=PRMT1 PE=1 SV=3 4.49 2418.6 - 2.38E+06 - - - -1.2548 - 2.877 0.259 - 411.2 1 2 1 -0.0017 12 0 0 0 2.83E+08 1.30E+08 - - - 4.3563 1 221125_WJC_METTL3_EV_vs_WT_F05.12628.12628.3 7.48E-06 14/56 R.TPVIDADKPVSSQLR.V "sp|Q14204|DYHC1_HUMAN,tr|A0A7P0T8N2|A0A7P0T8N2_HUMAN,tr|A0A7P0T9C4|A0A7P0T9C4_HUMAN,tr|A0A7P0TBJ7|A0A7P0TBJ7_HUMAN,tr|A0A804HHY6|A0A804HHY6_HUMAN,tr|A0A7P0T9K2|A0A7P0T9K2_HUMAN,tr|A0A7P0TB64|A0A7P0TB64_HUMAN,tr|A0A2R8Y706|A0A2R8Y706_HUMAN,tr|A0A7P0T916|A0A7P0T916_HUMAN,tr|A0A7P0TB75|A0A7P0TB75_HUMAN,tr|A0A7P0T8W5|A0A7P0T8W5_HUMAN,tr|A0A7P0T9S3|A0A7P0T9S3_HUMAN,tr|A0A7P0TAF3|A0A7P0TAF3_HUMAN,tr|A0A7P0T9F1|A0A7P0T9F1_HUMAN,tr|A0A7P0TAW9|A0A7P0TAW9_HUMAN,tr|A0A2R8YGC7|A0A2R8YGC7_HUMAN,tr|A0A7P0TA13|A0A7P0TA13_HUMAN,tr|A0A7P0T934|A0A7P0T934_HUMAN,tr|A0A7P0TAV5|A0A7P0TAV5_HUMAN,tr|A0A7P0T9Y3|A0A7P0T9Y3_HUMAN,tr|A0A7P0T7V5|A0A7P0T7V5_HUMAN,tr|A0A7P0T9R4|A0A7P0T9R4_HUMAN,tr|A0A2R8Y5T0|A0A2R8Y5T0_HUMAN,tr|A0A7P0T990|A0A7P0T990_HUMAN,tr|A0A7P0T942|A0A7P0T942_HUMAN,tr|A0A7P0TAS7|A0A7P0TAS7_HUMAN,tr|A0A2R8YFZ7|A0A2R8YFZ7_HUMAN,tr|A0A7P0T825|A0A7P0T825_HUMAN,tr|A0A2R8Y6H2|A0A2R8Y6H2_HUMAN,tr|A0A7P0TBC9|A0A7P0TBC9_HUMAN,tr|A0A7P0TAM4|A0A7P0TAM4_HUMAN" 31 1624.8784 0.92 64661 12628 3 1624.876926 542.6334 Cytoplasmic dynein 1 heavy chain 1 OS=Homo sapiens OX=9606 GN=DYNC1H1 PE=1 SV=5 5.63 2418.7 - 3.25E+06 - - - -0.9287 - 2.706 0.483 - 217.8 1 2 0 -0.0015 15 0 0 0 2.12E+07 2.31E+07 - - - 6.5221 1 221125_WJC_METTL3_EV_vs_WT_F05.12629.12629.3 0.00157 Dec-48 R.VAIHYINPPNPAK.D "sp|P78406|RAE1L_HUMAN,tr|E9PQ57|E9PQ57_HUMAN" 2 1432.7827 1.62 64662 12629 3 1432.783741 478.6015 mRNA export factor OS=Homo sapiens OX=9606 GN=RAE1 PE=1 SV=1 8.57 2418.7 - 2.25E+06 - - - 0.7377 - 2.484 0.481 - 214.8 1 2 0 0.0011 13 0 0 0 2.39E+07 1.48E+07 - - - 6.3693 0.9044 221125_WJC_METTL3_EV_vs_WT_F05.12630.12630.3 4.12E-05 Sep-44 R.AQVQEFC[160.03]DYGTK[136.11].E "sp|Q86U44|MTA70_HUMAN,tr|H0YFV6|H0YFV6_HUMAN" 2 1452.6435 0.07 64663 12630 3 1453.63629 485.2218 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 4.37 2418.8 - 1.67E+06 - - - 683.4506 - 1.848 0.534 - 100.5 1 2 0 0.9928 12 0 0 0 1.57E+06 2.14E+07 - - - 5.9208 1 221125_WJC_METTL3_EV_vs_WT_F05.12631.12631.2 6.09E-09 24-Dec K.DMYNDTLNGSTEK[136.11].R sp|Q96PU8|QKI_HUMAN 1 1494.6388 2.62 64664 12631 2 1494.635403 748.3267 Protein quaking OS=Homo sapiens OX=9606 GN=QKI PE=1 SV=1 4.03 2418.9 - 1.61E+06 - - - -2.2648 - 2.491 0.716 - 396.5 1 2 0 -0.0034 13 0 0 0 4.06E+07 1.55E+07 - - - 6.6707 0.9995 221125_WJC_METTL3_EV_vs_WT_F05.12633.12633.2 1.61E-06 22-Oct R.LTWHSC[160.03]PEDEAQ.- sp|Q13185|CBX3_HUMAN 1 1471.6038 - 64666 12633 2 1471.599144 736.8092 Chromobox protein homolog 3 OS=Homo sapiens OX=9606 GN=CBX3 PE=1 SV=4 4.13 2419 - 1.34E+06 - - - -3.1598 - 2.046 0.611 - 221.4 1 2 0 -0.0046 12 0 0 0 - - - - - 5.436 1 221125_WJC_METTL3_EV_vs_WT_F05.12635.12635.3 4.46E-06 Nov-48 R.K[136.11]ASGPPVSELITK[136.11].A "sp|P10412|H14_HUMAN,sp|P16403|H12_HUMAN,sp|P16402|H13_HUMAN" 3 1341.7839 0.88 64668 12635 3 1341.783323 448.2686 Histone H1.4 OS=Homo sapiens OX=9606 GN=H1-4 PE=1 SV=2 8.59 2419.2 - 640224 - - - -0.4054 - 2.578 0.457 - 215.6 1 2 0 -0.0005 13 0 0 0 2.16E+07 2.45E+07 - - - 6.2026 0.9984 221125_WJC_METTL3_EV_vs_WT_F05.12636.12636.2 0.00353 26-Nov K.TVSPDR[166.11]LELEAAQK[136.11].F "sp|Q14974|IMB1_HUMAN,tr|J3QR48|J3QR48_HUMAN" 2 1573.8431 1.33 64669 12636 2 1573.842511 787.9288 Importin subunit beta-1 OS=Homo sapiens OX=9606 GN=KPNB1 PE=1 SV=2 4.68 2419.3 - 505330 - - - -0.3463 - 2.658 0.423 - 298.4 1 2 1 -0.0005 14 0 0 0 7.89E+06 5.91E+06 - - - 4.6183 0.9998 221125_WJC_METTL3_EV_vs_WT_F05.12637.12637.2 0.00355 16-Nov R.K[136.11]QVEELFER[166.11].K "sp|P78347|GTF2I_HUMAN,tr|A0A494C1K3|A0A494C1K3_HUMAN" 2 1194.6364 1.54 64670 12637 2 1194.635463 598.3255 General transcription factor II-I OS=Homo sapiens OX=9606 GN=GTF2I PE=1 SV=2 4.79 2419.4 - 431624 - - - -0.7492 - 2.27 0.342 - 511.2 1 2 0 -0.0009 9 0 0 0 1.26E+08 8.18E+07 - - - 3.9384 0.9988 221125_WJC_METTL3_EV_vs_WT_F05.12638.12638.2 0.00333 16-Jul K.TQYDFPSC[160.03]R.C "sp|Q6N021|TET2_HUMAN,tr|E7EQS8|E7EQS8_HUMAN,tr|E7EPB1|E7EPB1_HUMAN" 3 1172.4921 30.49 64671 12638 2 1172.494512 587.2533 Methylcytosine dioxygenase TET2 OS=Homo sapiens OX=9606 GN=TET2 PE=1 SV=3 5.5 2419.6 - 364455 - - - 2.093 - 1.367 0.424 - 170 1 2 0 0.0025 9 0 0 0 2.32E+06 7.60E+04 - - - 3.0763 0.9934 221125_WJC_METTL3_EV_vs_WT_F05.12639.12639.2 0.00935 22-Jul K.LK[136.11]QSLPPGLAVK[136.11].E sp|P63173|RL38_HUMAN 1 1265.8042 0.83 64672 12639 2 1265.805224 633.9094 60S ribosomal protein L38 OS=Homo sapiens OX=9606 GN=RPL38 PE=1 SV=2 10 2419.7 - 306151 - - - 0.8027 - 1.533 0.391 - 102.9 1 2 1 0.001 12 0 0 0 7.57E+05 9.13E+05 - - - 3.0527 0.9562 221125_WJC_METTL3_EV_vs_WT_F05.12641.12641.2 0.367 18-Jun K.K[136.11]FSEDFGQES.- sp|Q9UN37|VPS4A_HUMAN 1 1180.5128 2.27 64674 12641 2 1180.507409 591.2637 Vacuolar protein sorting-associated protein 4A OS=Homo sapiens OX=9606 GN=VPS4A PE=1 SV=1 4.14 2420 - 277338 - - - -4.5523 - 1.199 0.253 - 94.3 1 2 0 -0.0054 10 0 0 0 4.67E+06 2.06E+06 - - - 1.4146 0.9875 221125_WJC_METTL3_EV_vs_WT_F05.12643.12643.2 0.0104 22-Jul K.LKQSLPPGLAVK.E sp|P63173|RL38_HUMAN 1 1249.7758 0.79 64676 12643 2 1249.77529 625.8952 60S ribosomal protein L38 OS=Homo sapiens OX=9606 GN=RPL38 PE=1 SV=2 10 2420.2 - 180950 - - - -0.4145 - 1.829 0.223 - 119.6 1 2 1 -0.0005 12 0 0 0 9.20E+05 1.16E+06 - - - 2.2765 0.9998 221125_WJC_METTL3_EV_vs_WT_F05.12646.12646.3 7.58E-05 14/44 K.GKPDLNTALPVR.Q "sp|O95983|MBD3_HUMAN,tr|A0A087X1H1|A0A087X1H1_HUMAN,tr|K7EIE8|K7EIE8_HUMAN,tr|A0A087WT34|A0A087WT34_HUMAN,tr|A0A0A0MTS6|A0A0A0MTS6_HUMAN" 5 1279.7248 1.67 64678 12646 3 1279.724716 427.5822 Methyl-CpG-binding domain protein 3 OS=Homo sapiens OX=9606 GN=MBD3 PE=1 SV=1 8.75 2420.6 - 2.92E+06 - - - -0.093 - 2.153 0.359 - 254.3 1 2 0 -0.0001 12 0 0 0 8.83E+07 5.29E+07 - - - 4.6681 0.9999 221125_WJC_METTL3_EV_vs_WT_F05.12647.12647.3 1.36E-05 Dec-56 R.LGLHQQGSEPSYLDR[166.11].T "sp|Q9BV38|WDR18_HUMAN,tr|U3KQC1|U3KQC1_HUMAN,tr|A0A0A0MQU0|A0A0A0MQU0_HUMAN" 3 1708.8408 1.18 64679 12647 3 1708.839548 570.6209 WD repeat-containing protein 18 OS=Homo sapiens OX=9606 GN=WDR18 PE=1 SV=2 5.32 2420.7 - 510038 - - - -0.7432 - 2.541 0.429 - 185.7 1 2 0 -0.0013 15 0 0 0 7.94E+07 6.75E+07 - - - 5.756 0.9999 221125_WJC_METTL3_EV_vs_WT_F05.12648.12648.2 3.66E-05 20-Nov K.ASLENSLEETK.G "sp|P02533|K1C14_HUMAN,sp|P08779|K1C16_HUMAN,tr|K7ENW6|K7ENW6_HUMAN" 3 1219.5932 54.26 64680 12648 2 1219.592879 610.8039 "Keratin, type I cytoskeletal 14 OS=Homo sapiens OX=9606 GN=KRT14 PE=1 SV=4" 4.25 2420.8 - 5.29E+06 - - - -0.273 - 2.585 0.494 - 318.2 1 2 0 -0.0003 11 0 0 0 1.78E+08 3.28E+06 - - - 5.2588 0.9996 221125_WJC_METTL3_EV_vs_WT_F05.12650.12650.3 0.00255 13/32 R.KQVEELFER.K "sp|P78347|GTF2I_HUMAN,tr|A0A494C1K3|A0A494C1K3_HUMAN" 2 1176.6139 1.44 64682 12650 3 1176.612541 393.2119 General transcription factor II-I OS=Homo sapiens OX=9606 GN=GTF2I PE=1 SV=2 4.79 2420.9 - 3.04E+06 - - - -1.1448 - 2.507 0.243 - 309.8 1 2 0 -0.0013 9 0 0 0 2.00E+08 1.39E+08 - - - 4.0188 1 221125_WJC_METTL3_EV_vs_WT_F05.12651.12651.3 4.49E-06 Dec-32 R.K[136.11]QVEELFER[166.11].K "sp|P78347|GTF2I_HUMAN,tr|A0A494C1K3|A0A494C1K3_HUMAN" 2 1194.6364 1.43 64683 12651 3 1194.635549 399.2194 General transcription factor II-I OS=Homo sapiens OX=9606 GN=GTF2I PE=1 SV=2 4.79 2421 - 2.96E+06 - - - -0.6772 - 2.289 0.478 - 309.7 1 2 0 -0.0008 9 0 0 0 1.99E+08 1.39E+08 - - - 6.3648 0.9998 221125_WJC_METTL3_EV_vs_WT_F05.12652.12652.2 0.0077 16-Nov R.KQVEELFER.K "sp|P78347|GTF2I_HUMAN,tr|A0A494C1K3|A0A494C1K3_HUMAN" 2 1176.6139 1.54 64684 12652 2 1176.613531 589.3142 General transcription factor II-I OS=Homo sapiens OX=9606 GN=GTF2I PE=1 SV=2 4.79 2421 - 2.16E+06 - - - -0.3034 - 2.322 0.377 - 570.6 1 2 0 -0.0004 9 0 0 0 1.26E+08 8.17E+07 - - - 4.2626 0.9999 221125_WJC_METTL3_EV_vs_WT_F05.12653.12653.3 1.91E-05 Oct-44 K.STYEQVDLIGK[136.11]K[136.11].T sp|Q9NR30|DDX21_HUMAN 1 1395.758 0.93 64685 12653 3 1395.758891 466.26 Nucleolar RNA helicase 2 OS=Homo sapiens OX=9606 GN=DDX21 PE=1 SV=5 5.79 2421.1 - 1.95E+06 - - - 0.6054 - 1.984 0.485 - 111.3 1 2 0 0.0008 12 0 0 0 2.35E+07 2.54E+07 - - - 5.8461 0.9997 221125_WJC_METTL3_EV_vs_WT_F05.12654.12654.3 0.00338 Nov-44 K.STYEQVDLIGKK.T sp|Q9NR30|DDX21_HUMAN 1 1379.7296 0.79 64686 12654 3 1379.72817 460.9172 Nucleolar RNA helicase 2 OS=Homo sapiens OX=9606 GN=DDX21 PE=1 SV=5 5.79 2421.1 - 1.90E+06 - - - -1.0698 - 1.947 0.348 - 95.5 1 2 0 -0.0015 12 0 0 0 2.46E+07 3.11E+07 - - - 4.2663 1 221125_WJC_METTL3_EV_vs_WT_F05.12655.12655.3 4.37E-05 15/44 K.KPSISITTESLK.S "sp|Q9UKV3|ACINU_HUMAN,tr|G3V3B0|G3V3B0_HUMAN,tr|S4R3H4|S4R3H4_HUMAN,tr|E7EQT4|E7EQT4_HUMAN,tr|G3V3T3|G3V3T3_HUMAN" 5 1302.7395 1.59 64687 12655 3 1302.738057 435.2538 Apoptotic chromatin condensation inducer in the nucleus OS=Homo sapiens OX=9606 GN=ACIN1 PE=1 SV=2 8.59 2421.2 - 1.33E+06 - - - -1.0938 - 2.605 0.45 - 542.8 1 2 0 -0.0014 12 0 0 0 2.22E+07 1.40E+07 - - - 6.2105 0.9995 221125_WJC_METTL3_EV_vs_WT_F05.12656.12656.3 0.000395 Dec-36 R.LEK[136.11]HELIEFR[166.11].R "sp|Q00610|CLH1_HUMAN,tr|K7EJJ5|K7EJJ5_HUMAN,tr|J3KS13|J3KS13_HUMAN,tr|A0A087WVQ6|A0A087WVQ6_HUMAN" 4 1330.7364 0.77 64688 12656 3 1330.73555 444.5861 Clathrin heavy chain 1 OS=Homo sapiens OX=9606 GN=CLTC PE=1 SV=5 5.5 2421.3 - 820424 - - - -0.6433 - 2.344 0.372 - 215.7 1 2 1 -0.0009 10 0 0 0 3.47E+06 4.52E+06 - - - 5.175 0.999 221125_WJC_METTL3_EV_vs_WT_F05.12657.12657.2 4.24E-06 14/22 K.GK[136.11]VEEVELPVEK[136.11].V "sp|Q99873|ANM1_HUMAN,sp|Q9NR22|ANM8_HUMAN,tr|E9PQ98|E9PQ98_HUMAN,tr|E9PKG1|E9PKG1_HUMAN,tr|E9PNR9|E9PNR9_HUMAN,tr|H0YDE4|H0YDE4_HUMAN,tr|E9PIX6|E9PIX6_HUMAN" 7 1370.7628 2.17 64689 12657 2 1370.761946 686.3887 Protein arginine N-methyltransferase 1 OS=Homo sapiens OX=9606 GN=PRMT1 PE=1 SV=3 4.49 2421.4 - 711054 - - - -0.6208 - 2.897 0.506 - 683.2 1 2 1 -0.0009 12 0 0 0 3.93E+07 1.81E+07 - - - 5.5768 0.9985 221125_WJC_METTL3_EV_vs_WT_F05.12659.12659.3 0.000172 16/44 K.NFGEDMDDERLK.D "sp|Q9H361|PABP3_HUMAN,sp|P11940|PABP1_HUMAN,tr|A0A7I2YQE4|A0A7I2YQE4_HUMAN,tr|A0A7I2V649|A0A7I2V649_HUMAN,tr|H0YAR2|H0YAR2_HUMAN,tr|E7ERJ7|E7ERJ7_HUMAN,tr|A0A7I2YQ88|A0A7I2YQ88_HUMAN,tr|H0YBN4|H0YBN4_HUMAN,tr|A0A087WTT1|A0A087WTT1_HUMAN,tr|A0A7I2YQ90|A0A7I2YQ90_HUMAN,tr|A0A7I2V4N4|A0A7I2V4N4_HUMAN,tr|E7EQV3|E7EQV3_HUMAN" 12 1467.63 1.4 64691 12659 3 1467.62906 490.2173 Polyadenylate-binding protein 3 OS=Homo sapiens OX=9606 GN=PABPC3 PE=1 SV=2 4.11 2421.7 - 553046 - - - -0.6459 - 2.867 0.242 - 389.7 1 2 1 -0.0009 12 0 0 0 1.32E+08 9.47E+07 - - - 4.1573 0.9548 221125_WJC_METTL3_EV_vs_WT_F05.12661.12661.2 0.00103 15/30 K.VIAQQVQLQQQQEQVR[166.11].L sp|Q01664|TFAP4_HUMAN 1 1932.0416 2.35 64693 12661 2 1933.037277 967.0281 Transcription factor AP-4 OS=Homo sapiens OX=9606 GN=TFAP4 PE=1 SV=2 5.97 2421.9 - 384418 - - - 515.3274 - 3.08 0.449 - 992.9 1 2 0 0.9956 16 0 0 0 8.69E+06 3.69E+06 - - - 4.8104 1 221125_WJC_METTL3_EV_vs_WT_F05.12663.12663.3 7.21E-05 14/48 K.TLQEVTEMDSVKR.Y "sp|P58107|EPIPL_HUMAN,sp|P58107|EPIPL_HUMAN,sp|P58107|EPIPL_HUMAN,sp|P58107|EPIPL_HUMAN,tr|A0A075B730|A0A075B730_HUMAN,tr|A0A075B730|A0A075B730_HUMAN,tr|A0A075B730|A0A075B730_HUMAN,tr|A0A075B730|A0A075B730_HUMAN" 8 1534.7661 1.21 64695 12663 3 1534.76613 512.596 Epiplakin OS=Homo sapiens OX=9606 GN=EPPK1 PE=1 SV=3 4.68 2422.2 - 259136 - - - 0.0143 - 2.725 0.481 - 221.8 1 2 0 0 13 0 0 0 2.07E+07 1.71E+07 - - - 6.6207 0.9983 221125_WJC_METTL3_EV_vs_WT_F05.12664.12664.3 0.00524 Sep-36 K.TALNSFMHSK[136.11].E "sp|O60524|NEMF_HUMAN,tr|G3V5V3|G3V5V3_HUMAN" 2 1142.5634 0.01 64696 12664 3 1142.562769 381.8617 Nuclear export mediator factor NEMF OS=Homo sapiens OX=9606 GN=NEMF PE=1 SV=4 8.44 2422.3 - 190281 - - - -0.5339 - 1.513 0.285 - 85.4 1 2 0 -0.0006 10 0 0 0 1.70E+04 2.44E+06 - - - 2.9266 1 221125_WJC_METTL3_EV_vs_WT_F05.12665.12665.2 1.36E-10 24-Dec N.ASC[160.03]TTNC[160.03]LAPLAK.V "sp|O14556|G3PT_HUMAN,sp|P04406|G3P_HUMAN,tr|K7EP73|K7EP73_HUMAN,tr|E7EUT5|E7EUT5_HUMAN" 4 1405.6694 0.96 64697 12665 2 1405.669111 703.842 "Glyceraldehyde-3-phosphate dehydrogenase, testis-specific OS=Homo sapiens OX=9606 GN=GAPDHS PE=1 SV=2" 8.1 2422.5 - 190191 - - - -0.185 - 2.4 0.673 - 416.2 1 1 0 -0.0003 13 0 0 0 8.08E+06 8.38E+06 - - - 6.2586 1 221125_WJC_METTL3_EV_vs_WT_F05.12668.12668.3 1.99E-07 15/44 K.NFGEDMDDER[166.11]LK[136.11].D "sp|Q9H361|PABP3_HUMAN,sp|P11940|PABP1_HUMAN,tr|A0A7I2YQE4|A0A7I2YQE4_HUMAN,tr|A0A7I2V649|A0A7I2V649_HUMAN,tr|H0YAR2|H0YAR2_HUMAN,tr|E7ERJ7|E7ERJ7_HUMAN,tr|A0A7I2YQ88|A0A7I2YQ88_HUMAN,tr|H0YBN4|H0YBN4_HUMAN,tr|A0A087WTT1|A0A087WTT1_HUMAN,tr|A0A7I2YQ90|A0A7I2YQ90_HUMAN,tr|A0A7I2V4N4|A0A7I2V4N4_HUMAN,tr|E7EQV3|E7EQV3_HUMAN" 12 1485.6525 1.4 64698 12668 3 1485.652034 496.2248 Polyadenylate-binding protein 3 OS=Homo sapiens OX=9606 GN=PABPC3 PE=1 SV=2 4.11 2422.9 - 3.33E+06 - - - -0.2989 - 2.924 0.62 - 363.3 1 2 1 -0.0004 12 0 0 0 1.32E+08 9.46E+07 - - - 8.4263 0.9999 221125_WJC_METTL3_EV_vs_WT_F05.12669.12669.3 2.30E-05 13/48 R.TGLYNYYDDEKEK.L "sp|P50454|SERPH_HUMAN,tr|E9PKH2|E9PKH2_HUMAN,tr|E9PPV6|E9PPV6_HUMAN,tr|E9PR70|E9PR70_HUMAN,tr|E9PJH8|E9PJH8_HUMAN" 5 1636.7257 1.72 64699 12669 3 1636.723242 546.5825 Serpin H1 OS=Homo sapiens OX=9606 GN=SERPINH1 PE=1 SV=2 4.32 2422.9 - 2.16E+06 - - - -1.4914 - 2.484 0.59 - 132 1 2 1 -0.0024 13 0 0 0 3.78E+07 2.20E+07 - - - 7.5842 0.9999 221125_WJC_METTL3_EV_vs_WT_F05.12671.12671.3 5.93E-07 Nov-48 R.TGLYNYYDDEK[136.11]EK[136.11].L "sp|P50454|SERPH_HUMAN,tr|E9PKH2|E9PKH2_HUMAN,tr|E9PPV6|E9PPV6_HUMAN,tr|E9PR70|E9PR70_HUMAN,tr|E9PJH8|E9PJH8_HUMAN" 5 1652.7541 1.72 64701 12671 3 1652.752336 551.9253 Serpin H1 OS=Homo sapiens OX=9606 GN=SERPINH1 PE=1 SV=2 4.32 2423.1 - 1.64E+06 - - - -1.057 - 2.221 0.579 - 99 1 2 1 -0.0017 13 0 0 0 3.78E+07 2.20E+07 - - - 7.1583 1 221125_WJC_METTL3_EV_vs_WT_F05.12672.12672.2 1.05E-07 17/22 K.GKVEEVELPVEK.V "sp|Q99873|ANM1_HUMAN,sp|Q9NR22|ANM8_HUMAN,tr|E9PQ98|E9PQ98_HUMAN,tr|E9PKG1|E9PKG1_HUMAN,tr|E9PNR9|E9PNR9_HUMAN,tr|H0YDE4|H0YDE4_HUMAN,tr|E9PIX6|E9PIX6_HUMAN" 7 1354.7344 2.17 64702 12672 2 1354.735632 678.3745 Protein arginine N-methyltransferase 1 OS=Homo sapiens OX=9606 GN=PRMT1 PE=1 SV=3 4.49 2423.2 - 1.49E+06 - - - 0.9116 - 3.099 0.594 - 995.6 1 2 1 0.0012 12 0 0 0 3.93E+07 1.81E+07 - - - 6.404 1 221125_WJC_METTL3_EV_vs_WT_F05.12673.12673.3 4.52E-07 16/48 R.KASGPPVSELITK.A "sp|P10412|H14_HUMAN,sp|P16403|H12_HUMAN,sp|P16402|H13_HUMAN" 3 1325.7555 0.88 64703 12673 3 1325.754527 442.9258 Histone H1.4 OS=Homo sapiens OX=9606 GN=H1-4 PE=1 SV=2 8.59 2423.3 - 788058 - - - -0.709 - 2.58 0.535 - 446.4 1 2 0 -0.0009 13 0 0 0 2.15E+07 2.45E+07 - - - 7.0742 0.9994 221125_WJC_METTL3_EV_vs_WT_F05.12676.12676.3 0.0027 Sep-36 K.AHWTPFEGQK[136.11].V "sp|P27708|PYR1_HUMAN,tr|F8VPD4|F8VPD4_HUMAN,tr|H7BZB3|H7BZB3_HUMAN" 3 1207.5866 0.64 64706 12676 3 1207.586233 403.5361 CAD protein OS=Homo sapiens OX=9606 GN=CAD PE=1 SV=3 6.79 2423.6 - 707334 - - - -0.2683 - 1.83 0.3 - 113.3 1 2 0 -0.0003 10 0 0 0 5.44E+06 8.46E+06 - - - 3.6495 0.9999 221125_WJC_METTL3_EV_vs_WT_F05.12677.12677.3 2.80E-05 Sep-44 K.K[136.11]PSISITTESLK[136.11].S "sp|Q9UKV3|ACINU_HUMAN,tr|G3V3B0|G3V3B0_HUMAN,tr|S4R3H4|S4R3H4_HUMAN,tr|E7EQT4|E7EQT4_HUMAN,tr|G3V3T3|G3V3T3_HUMAN" 5 1318.7679 1.57 64707 12677 3 1318.766864 440.5966 Apoptotic chromatin condensation inducer in the nucleus OS=Homo sapiens OX=9606 GN=ACIN1 PE=1 SV=2 8.59 2423.7 - 705181 - - - -0.7719 - 2.207 0.407 - 170.8 1 2 0 -0.001 12 0 0 0 9.81E+06 6.23E+06 - - - 5.2717 1 221125_WJC_METTL3_EV_vs_WT_F05.12684.12684.3 1.04E-05 16/52 K.VGDDVEFEVSSDR[166.11]R[166.11].T "sp|O75534|CSDE1_HUMAN,tr|E9PLD4|E9PLD4_HUMAN" 2 1628.7545 0.6 64712 12684 3 1628.753687 543.9254 Cold shock domain-containing protein E1 OS=Homo sapiens OX=9606 GN=CSDE1 PE=1 SV=2 4.11 2424.5 - 1.72E+06 - - - -0.5108 - 2.487 0.486 - 449.1 1 2 0 -0.0008 14 0 0 0 2.03E+07 3.37E+07 - - - 6.3794 1 221125_WJC_METTL3_EV_vs_WT_F05.12686.12686.3 0.000368 15/48 R.VAIHYINPPNPAK[136.11].D "sp|P78406|RAE1L_HUMAN,tr|E9PQ57|E9PQ57_HUMAN" 2 1440.7969 1.98 64714 12686 3 1440.797556 481.2729 mRNA export factor OS=Homo sapiens OX=9606 GN=RAE1 PE=1 SV=1 8.57 2424.7 - 1.64E+06 - - - 0.4664 - 2.813 0.446 - 461 1 2 0 0.0007 13 0 0 0 5.87E+07 2.96E+07 - - - 6.3164 0.9999 221125_WJC_METTL3_EV_vs_WT_F05.12689.12689.3 4.18E-05 Sep-36 K.K[136.11]PEMFETAIK[136.11].E "sp|P78347|GTF2I_HUMAN,tr|A0A494C1K3|A0A494C1K3_HUMAN" 2 1208.6446 12.07 64717 12689 3 1208.644007 403.8888 General transcription factor II-I OS=Homo sapiens OX=9606 GN=GTF2I PE=1 SV=2 6.14 2425.1 - 533973 - - - -0.4873 - 2.279 0.416 - 120.5 1 2 0 -0.0006 10 0 0 0 9.47E+07 7.85E+06 - - - 5.5835 0.9999 221125_WJC_METTL3_EV_vs_WT_F05.12690.12690.3 8.00E-05 14/60 K.VIAQQVQLQQQQEQVR[166.11].L sp|Q01664|TFAP4_HUMAN 1 1932.0416 1.93 64718 12690 3 1932.043031 645.0212 Transcription factor AP-4 OS=Homo sapiens OX=9606 GN=TFAP4 PE=1 SV=2 5.97 2425.2 - 314321 - - - 0.7184 - 2.223 0.421 - 298.8 1 2 0 0.0014 16 0 0 0 5.63E+07 2.93E+07 - - - 5.2831 0.9996 221125_WJC_METTL3_EV_vs_WT_F05.12691.12691.2 0.204 18-Nov K.K[136.11]PEMFETAIK[136.11].E "sp|P78347|GTF2I_HUMAN,tr|A0A494C1K3|A0A494C1K3_HUMAN" 2 1208.6446 1.31 64719 12691 2 1208.645989 605.3296 General transcription factor II-I OS=Homo sapiens OX=9606 GN=GTF2I PE=1 SV=2 6.14 2425.3 - 294470 - - - 1.1525 - 2.078 0.35 - 315.4 1 2 0 0.0014 10 0 0 0 5.49E+06 4.19E+06 - - - 3.6672 0.9999 221125_WJC_METTL3_EV_vs_WT_F05.12699.12699.2 8.96E-07 20-Nov K.LTDNGTEFSVK.V "sp|P52732|KIF11_HUMAN,tr|A0A7I2YQY4|A0A7I2YQY4_HUMAN,tr|A0A7I2V3A9|A0A7I2V3A9_HUMAN,tr|A0A7I2V3V3|A0A7I2V3V3_HUMAN" 4 1209.5877 6.29 64725 12699 2 1209.587327 605.8011 Kinesin-like protein KIF11 OS=Homo sapiens OX=9606 GN=KIF11 PE=1 SV=2 4.37 2426.4 - 511914 - - - -0.3357 - 2.31 0.519 - 314.5 1 2 0 -0.0004 11 0 0 0 8.22E+06 1.31E+06 - - - 5.1392 0.9893 221125_WJC_METTL3_EV_vs_WT_F05.12700.12700.2 3.80E-05 26-Oct L.GAGQASLFGNNQPK.L "sp|P52948|NUP98_HUMAN,tr|A0A3B3ITD8|A0A3B3ITD8_HUMAN,tr|H0YEN4|H0YEN4_HUMAN" 3 1387.6844 4.14 64726 12700 2 1387.683855 694.8495 Nuclear pore complex protein Nup98-Nup96 OS=Homo sapiens OX=9606 GN=NUP98 PE=1 SV=4 8.75 2426.5 - 418563 - - - -0.4122 - 2.176 0.441 - 200 1 1 0 -0.0006 14 0 0 0 4.51E+06 1.09E+06 - - - 4.2491 1 221125_WJC_METTL3_EV_vs_WT_F05.12703.12703.2 6.28E-05 20-Nov R.YSFYSTC[160.03]SGQK.A sp|Q13835|PKP1_HUMAN 1 1326.5551 999 64729 12703 2 1326.550483 664.2848 Plakophilin-1 OS=Homo sapiens OX=9606 GN=PKP1 PE=1 SV=2 8.18 2426.9 - 214318 - - - -3.4443 - 2.266 0.629 - 348.8 1 2 0 -0.0046 11 0 0 0 4.35E+06 0.00E+00 - - - 5.8983 1 221125_WJC_METTL3_EV_vs_WT_F05.12706.12706.3 0.000136 16/48 K.GVAINMVTEEDKR.T sp|P60842|IF4A1_HUMAN 1 1460.7293 1.16 64731 12706 3 1460.731703 487.9171 Eukaryotic initiation factor 4A-I OS=Homo sapiens OX=9606 GN=EIF4A1 PE=1 SV=1 4.68 2427.2 - 1.75E+06 - - - 1.6259 - 2.857 0.458 - 309.8 1 2 0 0.0024 13 0 0 0 2.01E+07 1.74E+07 - - - 6.4918 0.8803 221125_WJC_METTL3_EV_vs_WT_F05.12708.12708.2 1.8 16-Jul K.KQEIKVEVK.E "sp|O43491|E41L2_HUMAN,tr|E9PIG0|E9PIG0_HUMAN,tr|A0A2R8Y5B3|A0A2R8Y5B3_HUMAN,tr|E9PII3|E9PII3_HUMAN,tr|E9PHY5|E9PHY5_HUMAN,tr|E9PK52|E9PK52_HUMAN,tr|E9PRG1|E9PRG1_HUMAN,tr|E9PQD2|E9PQD2_HUMAN" 8 1099.6601 999 64732 12708 2 1099.66044 550.8373 Band 4.1-like protein 2 OS=Homo sapiens OX=9606 GN=EPB41L2 PE=1 SV=1 8.5 2427.5 - 3.49E+06 - - - 0.3001 - 1.549 0.029 - 176.5 1 2 1 0.0003 9 0 0 0 5.23E+07 0.00E+00 - - - 0.5211 0.9993 221125_WJC_METTL3_EV_vs_WT_F05.12713.12713.3 0.000326 Dec-36 R.ETYTEDFIKK.Q sp|P82933|RT09_HUMAN 1 1272.6238 0.84 64737 12713 3 1272.627385 425.2152 "28S ribosomal protein S9, mitochondrial OS=Homo sapiens OX=9606 GN=MRPS9 PE=1 SV=2" 4.68 2428 - 535023 - - - 2.8296 - 2.056 0.346 - 136.9 1 2 0 0.0036 10 0 0 0 1.02E+07 1.22E+07 - - - 4.5015 0.9749 221125_WJC_METTL3_EV_vs_WT_F05.12714.12714.3 0.000385 Dec-44 F.QVAEVFTGHMGK.L sp|P06576|ATPB_HUMAN 1 1302.6391 1.41 64738 12714 3 1302.64043 435.2203 "ATP synthase subunit beta, mitochondrial OS=Homo sapiens OX=9606 GN=ATP5F1B PE=1 SV=3" 6.75 2428.1 - 520705 - - - 1.054 - 2.019 0.36 - 158.5 1 1 0 0.0014 12 0 0 0 1.16E+07 8.25E+06 - - - 4.5008 1 221125_WJC_METTL3_EV_vs_WT_F05.12720.12720.3 0.000166 15/48 K.TLQEVTEMDSVK[136.11]R[166.11].Y "sp|P58107|EPIPL_HUMAN,sp|P58107|EPIPL_HUMAN,sp|P58107|EPIPL_HUMAN,sp|P58107|EPIPL_HUMAN,tr|A0A075B730|A0A075B730_HUMAN,tr|A0A075B730|A0A075B730_HUMAN,tr|A0A075B730|A0A075B730_HUMAN,tr|A0A075B730|A0A075B730_HUMAN" 8 1552.7886 1.19 64742 12720 3 1552.790419 518.6035 Epiplakin OS=Homo sapiens OX=9606 GN=EPPK1 PE=1 SV=3 4.68 2428.8 - 1.41E+06 - - - 1.1856 - 2.611 0.479 - 240.1 1 2 0 0.0018 13 0 0 0 2.09E+07 1.75E+07 - - - 6.482 0.9994 221125_WJC_METTL3_EV_vs_WT_F05.12723.12723.2 0.000545 28-Nov R.GGGGNFGPGPGSNFR.G "sp|P22626|ROA2_HUMAN,tr|A0A024RA28|A0A024RA28_HUMAN,tr|A0A7I2V4N1|A0A7I2V4N1_HUMAN,tr|A0A7I2V4I6|A0A7I2V4I6_HUMAN,tr|A0A7I2V4S4|A0A7I2V4S4_HUMAN,tr|A0A7I2V323|A0A7I2V323_HUMAN,tr|A0A7I2V3P1|A0A7I2V3P1_HUMAN,tr|A0A7I2V3P7|A0A7I2V3P7_HUMAN" 8 1376.6222 1.36 64745 12723 2 1376.620174 689.3184 Heterogeneous nuclear ribonucleoproteins A2\B1 OS=Homo sapiens OX=9606 GN=HNRNPA2B1 PE=1 SV=2 9.75 2429.1 - 390162 - - - -1.4434 - 2.01 0.343 - 327.3 1 2 0 -0.002 15 0 0 0 1.37E+07 1.01E+07 - - - 3.2902 0.9976 221125_WJC_METTL3_EV_vs_WT_F05.12728.12728.2 0.15 22-May R.DYVAPTANLDQK.D sp|Q7KZF4|SND1_HUMAN 1 1333.6514 0.55 64750 12728 2 1333.650113 667.833 Staphylococcal nuclease domain-containing protein 1 OS=Homo sapiens OX=9606 GN=SND1 PE=1 SV=1 4.21 2429.8 - 114143 - - - -0.9613 - 1.178 0.314 - 63.6 1 2 0 -0.0013 12 0 0 0 1.41E+06 2.58E+06 - - - 1.7908 1 221125_WJC_METTL3_EV_vs_WT_F05.12731.12731.3 1.29E-08 17/52 K.VGDDVEFEVSSDRR.T "sp|O75534|CSDE1_HUMAN,tr|E9PLD4|E9PLD4_HUMAN" 2 1608.738 0.6 64751 12731 3 1608.741928 537.2533 Cold shock domain-containing protein E1 OS=Homo sapiens OX=9606 GN=CSDE1 PE=1 SV=2 4.11 2430.2 - 1.53E+06 - - - 2.4547 - 2.991 0.579 - 448.9 1 2 0 0.0039 14 0 0 0 2.03E+07 3.40E+07 - - - 7.9058 1 221125_WJC_METTL3_EV_vs_WT_F05.12732.12732.3 2.85E-06 Nov-36 R.ETYTEDFIK[136.11]K[136.11].Q sp|P82933|RT09_HUMAN 1 1288.6522 0.82 64752 12732 3 1288.651667 430.558 "28S ribosomal protein S9, mitochondrial OS=Homo sapiens OX=9606 GN=MRPS9 PE=1 SV=2" 4.68 2430.3 - 1.43E+06 - - - -0.4012 - 2.069 0.526 - 115.9 1 2 0 -0.0005 10 0 0 0 1.02E+07 1.24E+07 - - - 6.5276 0.9984 221125_WJC_METTL3_EV_vs_WT_F05.12733.12733.3 0.0314 Nov-44 K.QKWEAEPVYVQR.A "sp|P25311|ZA2G_HUMAN,tr|C9JEV0|C9JEV0_HUMAN" 2 1531.7783 48.48 64753 12733 3 1531.779789 511.6001 Zinc-alpha-2-glycoprotein OS=Homo sapiens OX=9606 GN=AZGP1 PE=1 SV=2 6.14 2430.4 - 1.30E+06 - - - 0.9544 - 2.219 0.307 - 159.7 1 2 1 0.0015 12 0 0 0 1.10E+07 2.27E+05 - - - 4.1717 0.8972 221125_WJC_METTL3_EV_vs_WT_F05.12734.12734.3 0.0906 Sep-40 R.QFSISESMKPK.F sp|Q9NRP4|SDHF3_HUMAN 1 1280.6435 1.47 64754 12734 3 1280.644704 427.8884 "Succinate dehydrogenase assembly factor 3, mitochondrial OS=Homo sapiens OX=9606 GN=SDHAF3 PE=1 SV=1" 8.59 2430.4 - 1.27E+06 - - - 0.9612 - 1.484 0.073 - 75.2 1 2 0 0.0012 11 0 0 0 1.44E+07 9.80E+06 - - - 0.4749 0.9955 221125_WJC_METTL3_EV_vs_WT_F05.12735.12735.3 1.50E-05 14/44 F.QVAEVFTGHMGK[136.11].L sp|P06576|ATPB_HUMAN 1 1310.6533 1.4 64755 12735 3 1310.654753 437.8917 "ATP synthase subunit beta, mitochondrial OS=Homo sapiens OX=9606 GN=ATP5F1B PE=1 SV=3" 6.75 2430.5 - 932948 - - - 1.1414 - 2.166 0.501 - 194.8 1 1 0 0.0015 12 0 0 0 1.16E+07 8.31E+06 - - - 6.2676 0.9999 221125_WJC_METTL3_EV_vs_WT_F05.12736.12736.2 1.14E-05 15/28 R.GGGGNFGPGPGSNFR[166.11].G "sp|P22626|ROA2_HUMAN,tr|A0A024RA28|A0A024RA28_HUMAN,tr|A0A7I2V4N1|A0A7I2V4N1_HUMAN,tr|A0A7I2V4I6|A0A7I2V4I6_HUMAN,tr|A0A7I2V4S4|A0A7I2V4S4_HUMAN,tr|A0A7I2V323|A0A7I2V323_HUMAN,tr|A0A7I2V3P1|A0A7I2V3P1_HUMAN,tr|A0A7I2V3P7|A0A7I2V3P7_HUMAN" 8 1386.6304 1.37 64756 12736 2 1386.630162 694.3225 Heterogeneous nuclear ribonucleoproteins A2\B1 OS=Homo sapiens OX=9606 GN=HNRNPA2B1 PE=1 SV=2 9.75 2430.6 - 569546 - - - -0.194 - 2.599 0.514 - 536.9 1 2 0 -0.0003 15 0 0 0 1.38E+07 1.01E+07 - - - 5.1855 0.978 221125_WJC_METTL3_EV_vs_WT_F05.12737.12737.2 0.199 22-Jul K.QEVSEEMEPHGK[136.11].T "sp|O43309|ZSC12_HUMAN,tr|A0A804HJ42|A0A804HJ42_HUMAN" 2 1406.6227 0.001 64757 12737 2 1406.625524 704.3186 Zinc finger and SCAN domain-containing protein 12 OS=Homo sapiens OX=9606 GN=ZSCAN12 PE=1 SV=2 4.48 2430.8 - 534932 - - - 1.9764 - 1.2 0.151 - 161.9 1 2 0 0.0028 12 0 0 0 0.00E+00 4.55E+06 - - - 0.6351 0.9999 221125_WJC_METTL3_EV_vs_WT_F05.12738.12738.3 0.00107 13/52 R.SSTPQHPLLLAQPR.N sp|Q8TEK3|DOT1L_HUMAN 1 1543.8471 2.31 64758 12738 3 1543.84918 515.623 "Histone-lysine N-methyltransferase, H3 lysine-79 specific OS=Homo sapiens OX=9606 GN=DOT1L PE=1 SV=3" 9.49 2430.9 - 442291 - - - 1.3628 - 2.33 0.387 - 222.5 1 2 0 0.0021 14 0 0 0 4.67E+06 2.02E+06 - - - 5.102 0.9987 221125_WJC_METTL3_EV_vs_WT_F05.12739.12739.2 5.35E-06 13/26 R.QYFPNDEDQVGAAK.A sp|P13674|P4HA1_HUMAN 1 1580.7107 3.93 64759 12739 2 1580.703215 791.3626 Prolyl 4-hydroxylase subunit alpha-1 OS=Homo sapiens OX=9606 GN=P4HA1 PE=1 SV=2 4.03 2431 - 401310 - - - -4.7358 - 2.282 0.615 - 523 1 2 0 -0.0075 14 0 0 0 4.66E+06 1.19E+06 - - - 5.6515 0.9947 221125_WJC_METTL3_EV_vs_WT_F05.12741.12741.2 2.23E-06 13/26 R.QYFPNDEDQVGAAK[136.11].A sp|P13674|P4HA1_HUMAN 1 1588.7249 3.93 64761 12741 2 1588.714338 795.3697 Prolyl 4-hydroxylase subunit alpha-1 OS=Homo sapiens OX=9606 GN=P4HA1 PE=1 SV=2 4.03 2431.3 - 228543 - - - -6.6487 - 2.173 0.611 - 436.4 1 2 0 -0.0106 14 0 0 0 4.66E+06 1.19E+06 - - - 5.4981 0.9999 221125_WJC_METTL3_EV_vs_WT_F05.12743.12743.2 2.14E-06 24-Oct R.AEYFDGSEPVQNR.V sp|Q9HCS7|SYF1_HUMAN 1 1510.6688 1.52 64763 12743 2 1510.67063 756.3417 Pre-mRNA-splicing factor SYF1 OS=Homo sapiens OX=9606 GN=XAB2 PE=1 SV=2 4.14 2431.5 - 144745 - - - 1.1876 - 2.203 0.573 - 294.1 1 2 0 0.0018 13 0 0 0 1.90E+06 1.25E+06 - - - 5.2997 0.9998 221125_WJC_METTL3_EV_vs_WT_F05.12744.12744.2 1.81E-05 Sep-32 R.LSQVSDSVSGQTVVDPK[136.11].G sp|O94906|PRP6_HUMAN 1 1752.8985 2.96 64764 12744 2 1752.898579 877.4565 Pre-mRNA-processing factor 6 OS=Homo sapiens OX=9606 GN=PRPF6 PE=1 SV=1 4.21 2431.7 - 82815.5 - - - 0.0399 - 1.759 0.484 - 141.6 1 2 0 0.0001 17 0 0 0 2.54E+06 8.56E+05 - - - 4.0043 0.9998 221125_WJC_METTL3_EV_vs_WT_F05.12746.12746.3 0.000151 15/48 K.GVAINMVTEEDK[136.11]R[166.11].T sp|P60842|IF4A1_HUMAN 1 1478.7518 1.16 64765 12746 3 1478.754992 493.9245 Eukaryotic initiation factor 4A-I OS=Homo sapiens OX=9606 GN=EIF4A1 PE=1 SV=1 4.68 2431.9 - 866045 - - - 2.1599 - 2.673 0.386 - 299.4 1 2 0 0.0032 13 0 0 0 2.01E+07 1.74E+07 - - - 5.5084 0.9615 221125_WJC_METTL3_EV_vs_WT_F05.12748.12748.3 0.144 Oct-36 R.EK[136.11]GNEILELK[136.11].C sp|P12270|TPR_HUMAN 1 1187.6733 2.97 64766 12748 3 1187.674548 396.8984 Nucleoprotein TPR OS=Homo sapiens OX=9606 GN=TPR PE=1 SV=3 4.79 2432.1 - 1.08E+06 - - - 1.0904 - 1.593 0.187 - 114.2 1 2 1 0.0013 10 0 0 0 2.10E+07 7.09E+06 - - - 1.9843 0.9998 221125_WJC_METTL3_EV_vs_WT_F05.12749.12749.2 0.00609 20-Oct R.DTC[160.03]NSSLASLR[166.11].L "sp|P78337|PITX1_HUMAN,sp|Q99697|PITX2_HUMAN,tr|D6RFI4|D6RFI4_HUMAN" 3 1232.5695 1.36 64767 12749 2 1232.571488 617.292 Pituitary homeobox 1 OS=Homo sapiens OX=9606 GN=PITX1 PE=1 SV=2 5.83 2432.2 - 1.16E+06 - - - 1.6372 - 2.206 0.57 - 407.6 1 2 0 0.002 11 0 0 0 1.31E+07 9.61E+06 - - - 5.3907 0.9996 221125_WJC_METTL3_EV_vs_WT_F05.12751.12751.2 0.0111 16-Oct R.QLDSIVGER.G "sp|P48668|K2C6C_HUMAN,sp|P13647|K2C5_HUMAN,sp|P02538|K2C6A_HUMAN,tr|F8W0C6|F8W0C6_HUMAN" 4 1015.5298 999 64769 12751 2 1015.53107 508.7722 "Keratin, type II cytoskeletal 6C OS=Homo sapiens OX=9606 GN=KRT6C PE=1 SV=3" 4.37 2432.4 - 1.02E+06 - - - 1.2269 - 2.093 0.358 - 511.8 1 2 0 0.0012 9 0 0 0 9.31E+06 0.00E+00 - - - 3.8216 0.9872 221125_WJC_METTL3_EV_vs_WT_F05.12752.12752.2 0.0154 18-Nov R.EKGNEILELK.C sp|P12270|TPR_HUMAN 1 1171.6449 4.17 64770 12752 2 1171.647668 586.8297 Nucleoprotein TPR OS=Homo sapiens OX=9606 GN=TPR PE=1 SV=3 4.79 2432.5 - 581811 - - - 2.4026 - 1.952 0.324 - 294 1 2 1 0.0028 10 0 0 0 4.52E+06 1.08E+06 - - - 3.3002 0.9985 221125_WJC_METTL3_EV_vs_WT_F05.12754.12754.3 2.02E-06 13/56 R.LLEDK[136.11]NGEVQNLAVK[136.11].C "sp|O75155|CAND2_HUMAN,sp|Q86VP6|CAND1_HUMAN,tr|A0A3B3ISC4|A0A3B3ISC4_HUMAN,tr|F8WBB8|F8WBB8_HUMAN,tr|F5H6I6|F5H6I6_HUMAN" 5 1684.9331 0.15 64772 12754 3 1684.935227 562.6516 Cullin-associated NEDD8-dissociated protein 2 OS=Homo sapiens OX=9606 GN=CAND2 PE=1 SV=3 4.68 2432.8 - 563860 - - - 1.292 - 2.589 0.299 - 170.2 1 2 1 0.0022 15 0 0 0 2.48E+06 1.64E+07 - - - 4.3552 1 221125_WJC_METTL3_EV_vs_WT_F05.12755.12755.3 0.00792 14/36 K.RLHVSNIPFR.F "sp|O43251|RFOX2_HUMAN,sp|Q9NWB1|RFOX1_HUMAN,sp|A6NFN3|RFOX3_HUMAN,tr|A0A6Q8PGE0|A0A6Q8PGE0_HUMAN,tr|A0A6Q8PH77|A0A6Q8PH77_HUMAN,tr|A0A286YEU2|A0A286YEU2_HUMAN,tr|A0A087X2B1|A0A087X2B1_HUMAN,tr|F8VR27|F8VR27_HUMAN,tr|B7Z1U7|B7Z1U7_HUMAN,tr|B0QYY6|B0QYY6_HUMAN,tr|B0QYV1|B0QYV1_HUMAN,tr|A0A6Q8PHA3|A0A6Q8PHA3_HUMAN,tr|A0A3B3ITL7|A0A3B3ITL7_HUMAN,tr|F8VZY7|F8VZY7_HUMAN,tr|B0QYY4|B0QYY4_HUMAN,tr|J3KNW3|J3KNW3_HUMAN,tr|F8VZG9|F8VZG9_HUMAN,tr|J3QRF4|J3QRF4_HUMAN,tr|F8VRS4|F8VRS4_HUMAN,tr|A0A6Q8PFM4|A0A6Q8PFM4_HUMAN,tr|S4R469|S4R469_HUMAN,tr|A0A804HKG7|A0A804HKG7_HUMAN,tr|A0A0G2JRA5|A0A0G2JRA5_HUMAN,tr|A0A804HJM2|A0A804HJM2_HUMAN,tr|J3QQZ2|J3QQZ2_HUMAN,tr|I3L1D4|I3L1D4_HUMAN,tr|B0QYY7|B0QYY7_HUMAN,tr|A0A0G2JSB3|A0A0G2JSB3_HUMAN" 28 1237.7044 1.19 64773 12755 3 1237.705639 413.5754 RNA binding protein fox-1 homolog 2 OS=Homo sapiens OX=9606 GN=RBFOX2 PE=1 SV=3 12 2432.9 - 542777 - - - 1.0221 - 3.016 0.397 - 341.2 1 2 0 0.0013 10 0 0 0 2.47E+06 2.07E+06 - - - 6.1898 0.9995 221125_WJC_METTL3_EV_vs_WT_F05.12756.12756.3 0.00392 Dec-56 R.LLEDKNGEVQNLAVK.C "sp|O75155|CAND2_HUMAN,sp|Q86VP6|CAND1_HUMAN,tr|A0A3B3ISC4|A0A3B3ISC4_HUMAN,tr|F8WBB8|F8WBB8_HUMAN,tr|F5H6I6|F5H6I6_HUMAN" 5 1668.9046 0.22 64774 12756 3 1668.908515 557.3088 Cullin-associated NEDD8-dissociated protein 2 OS=Homo sapiens OX=9606 GN=CAND2 PE=1 SV=3 4.68 2433.1 - 476061 - - - 2.3159 - 2.599 0.439 - 125.6 1 2 1 0.0039 15 0 0 0 2.48E+06 1.12E+07 - - - 5.9256 0.9999 221125_WJC_METTL3_EV_vs_WT_F05.12757.12757.3 0.0006 18/36 K.R[166.11]LHVSNIPFR[166.11].F "sp|O43251|RFOX2_HUMAN,sp|Q9NWB1|RFOX1_HUMAN,sp|A6NFN3|RFOX3_HUMAN,tr|A0A6Q8PGE0|A0A6Q8PGE0_HUMAN,tr|A0A6Q8PH77|A0A6Q8PH77_HUMAN,tr|A0A286YEU2|A0A286YEU2_HUMAN,tr|A0A087X2B1|A0A087X2B1_HUMAN,tr|F8VR27|F8VR27_HUMAN,tr|B7Z1U7|B7Z1U7_HUMAN,tr|B0QYY6|B0QYY6_HUMAN,tr|B0QYV1|B0QYV1_HUMAN,tr|A0A6Q8PHA3|A0A6Q8PHA3_HUMAN,tr|A0A3B3ITL7|A0A3B3ITL7_HUMAN,tr|F8VZY7|F8VZY7_HUMAN,tr|B0QYY4|B0QYY4_HUMAN,tr|J3KNW3|J3KNW3_HUMAN,tr|F8VZG9|F8VZG9_HUMAN,tr|J3QRF4|J3QRF4_HUMAN,tr|F8VRS4|F8VRS4_HUMAN,tr|A0A6Q8PFM4|A0A6Q8PFM4_HUMAN,tr|S4R469|S4R469_HUMAN,tr|A0A804HKG7|A0A804HKG7_HUMAN,tr|A0A0G2JRA5|A0A0G2JRA5_HUMAN,tr|A0A804HJM2|A0A804HJM2_HUMAN,tr|J3QQZ2|J3QQZ2_HUMAN,tr|I3L1D4|I3L1D4_HUMAN,tr|B0QYY7|B0QYY7_HUMAN,tr|A0A0G2JSB3|A0A0G2JSB3_HUMAN" 28 1257.7209 1.23 64775 12757 3 1257.722929 420.2476 RNA binding protein fox-1 homolog 2 OS=Homo sapiens OX=9606 GN=RBFOX2 PE=1 SV=3 12 2433.2 - 436229 - - - 1.6021 - 3.377 0.381 - 849.3 1 2 0 0.002 10 0 0 0 3.20E+06 2.60E+06 - - - 6.3414 0.9995 221125_WJC_METTL3_EV_vs_WT_F05.12758.12758.2 1.80E-06 14/24 K.TDGEPGPQGWSPR[166.11].E sp|Q9H773|DCTP1_HUMAN 1 1392.6298 0.46 64776 12758 2 1392.634323 697.3222 dCTP pyrophosphatase 1 OS=Homo sapiens OX=9606 GN=DCTPP1 PE=1 SV=1 4.37 2433.3 - 352635 - - - 3.2751 - 2.385 0.562 - 599 1 2 0 0.0046 13 0 0 0 2.22E+06 4.87E+06 - - - 5.4213 0.9996 221125_WJC_METTL3_EV_vs_WT_F05.12759.12759.2 0.000545 22-Oct R.RVTENLASLTPK.G sp|Q96DF8|ESS2_HUMAN 1 1327.746 1.81 64777 12759 2 1327.747384 664.8803 Splicing factor ESS-2 homolog OS=Homo sapiens OX=9606 GN=ESS2 PE=1 SV=1 8.75 2433.5 - 340995 - - - 1.0687 - 1.958 0.362 - 298 1 2 0 0.0014 12 0 0 0 3.27E+06 1.81E+06 - - - 3.4822 0.9999 221125_WJC_METTL3_EV_vs_WT_F05.12762.12762.2 5.78E-06 13/32 R.LSQVSDSVSGQTVVDPK.G sp|O94906|PRP6_HUMAN 1 1744.8843 2.96 64780 12762 2 1744.886677 873.4494 Pre-mRNA-processing factor 6 OS=Homo sapiens OX=9606 GN=PRPF6 PE=1 SV=1 4.21 2433.8 - 320216 - - - 1.3571 - 2.726 0.548 - 320.8 1 2 0 0.0024 17 0 0 0 2.54E+06 8.56E+05 - - - 5.5533 1 221125_WJC_METTL3_EV_vs_WT_F05.12766.12766.3 9.43E-06 14/36 R.AFESDVFHNR[166.11].T "sp|O14545|TRAD1_HUMAN,tr|F8VNX8|F8VNX8_HUMAN" 2 1230.5657 0.66 64784 12766 3 1230.56666 411.1958 TRAF-type zinc finger domain-containing protein 1 OS=Homo sapiens OX=9606 GN=TRAFD1 PE=1 SV=1 5.32 2434.4 - 292221 - - - 0.7761 - 2.523 0.58 - 232 1 2 0 0.001 10 0 0 0 1.15E+06 1.72E+06 - - - 7.7089 1 221125_WJC_METTL3_EV_vs_WT_F05.12767.12767.3 3.53E-09 18/68 K.FVTSTSDHFVEGQTVAAK[136.11].V "sp|Q14690|RRP5_HUMAN,tr|A0A3B3IUD7|A0A3B3IUD7_HUMAN" 2 1930.9516 0.66 64785 12767 3 1930.951135 644.6578 Protein RRP5 homolog OS=Homo sapiens OX=9606 GN=PDCD11 PE=1 SV=3 5.32 2434.5 - 281097 - - - -0.2444 - 2.82 0.609 - 232.8 1 2 0 -0.0005 18 0 0 0 1.15E+06 1.73E+06 - - - 7.9112 0.9997 221125_WJC_METTL3_EV_vs_WT_F05.12769.12769.3 0.000414 13/44 K.GKVEEVELPVEK.V "sp|Q99873|ANM1_HUMAN,sp|Q9NR22|ANM8_HUMAN,tr|E9PQ98|E9PQ98_HUMAN,tr|E9PKG1|E9PKG1_HUMAN,tr|E9PNR9|E9PNR9_HUMAN,tr|H0YDE4|H0YDE4_HUMAN,tr|E9PIX6|E9PIX6_HUMAN" 7 1354.7344 2.18 64786 12769 3 1354.736308 452.5854 Protein arginine N-methyltransferase 1 OS=Homo sapiens OX=9606 GN=PRMT1 PE=1 SV=3 4.49 2434.7 - 5.51E+06 - - - 1.4106 - 2.749 0.41 - 318.4 1 2 1 0.0019 12 0 0 0 2.83E+08 1.30E+08 - - - 5.9136 0.9966 221125_WJC_METTL3_EV_vs_WT_F05.12770.12770.2 0.0765 22-Jul R.R[166.11]VTENLASLTPK[136.11].G sp|Q96DF8|ESS2_HUMAN 1 1345.7684 1.81 64787 12770 2 1345.770299 673.8915 Splicing factor ESS-2 homolog OS=Homo sapiens OX=9606 GN=ESS2 PE=1 SV=1 8.75 2434.8 - 266156 - - - 1.3851 - 1.712 0.175 - 120.6 1 2 0 0.0019 12 0 0 0 3.27E+06 1.81E+06 - - - 1.7476 0.7646 221125_WJC_METTL3_EV_vs_WT_F05.12771.12771.3 2.31 Oct-36 R.EKGNEILELK.C sp|P12270|TPR_HUMAN 1 1171.6449 2.97 64788 12771 3 1171.646742 391.5556 Nucleoprotein TPR OS=Homo sapiens OX=9606 GN=TPR PE=1 SV=3 4.79 2434.9 - 2.93E+06 - - - 1.6123 - 1.885 0.051 - 119.3 1 2 1 0.0019 10 0 0 0 2.10E+07 7.09E+06 - - - 0.9594 1 221125_WJC_METTL3_EV_vs_WT_F05.12772.12772.2 1.45E-07 14/22 R.SSTDSLPGPISR.Q sp|Q9HCD5|NCOA5_HUMAN 1 1215.6095 2.29 64789 12772 2 1215.612284 608.812 Nuclear receptor coactivator 5 OS=Homo sapiens OX=9606 GN=NCOA5 PE=1 SV=2 5.55 2435 - 1.13E+06 - - - 2.2647 - 2.683 0.606 - 413.7 1 2 0 0.0028 12 0 0 0 3.31E+08 1.44E+08 - - - 6.1128 0.9998 221125_WJC_METTL3_EV_vs_WT_F05.12774.12774.2 5.96E-05 14/22 R.QVQLQQEAEPLK.Q "sp|Q9ULV3|CIZ1_HUMAN,tr|Q5SYW2|Q5SYW2_HUMAN,tr|F5H2X7|F5H2X7_HUMAN,tr|H0Y5D5|H0Y5D5_HUMAN,tr|Q9BTG3|Q9BTG3_HUMAN" 5 1409.7514 999 64791 12774 2 1409.753742 705.883 Cip1-interacting zinc finger protein OS=Homo sapiens OX=9606 GN=CIZ1 PE=1 SV=2 4.53 2435.2 - 789295 - - - 1.6301 - 2.842 0.494 - 818.9 1 2 0 0.0023 12 0 0 0 5.70E+06 0.00E+00 - - - 5.4372 0.9994 221125_WJC_METTL3_EV_vs_WT_F05.12777.12777.3 0.000505 Dec-48 R.APR[166.11]PTIINAENLK[136.11].G sp|Q5JSZ5|PRC2B_HUMAN 1 1453.8372 2.24 64794 12777 3 1453.841712 485.6197 Protein PRRC2B OS=Homo sapiens OX=9606 GN=PRRC2B PE=1 SV=2 8.79 2435.5 - 480307 - - - 3.1152 - 2.229 0.378 - 217 1 2 0 0.0045 13 0 0 0 1.63E+08 7.28E+07 - - - 4.9263 0.9999 221125_WJC_METTL3_EV_vs_WT_F05.12779.12779.2 0.000148 13/22 K.EAATSELQSIQR[166.11].L sp|O15119|TBX3_HUMAN 1 1341.6764 1.04 64796 12779 2 1341.67639 671.8455 T-box transcription factor TBX3 OS=Homo sapiens OX=9606 GN=TBX3 PE=1 SV=4 4.53 2435.8 - 389928 - - - 0.0089 - 2.669 0.51 - 832.3 1 2 0 0 12 0 0 0 1.48E+08 1.42E+08 - - - 5.3909 0.9999 221125_WJC_METTL3_EV_vs_WT_F05.12781.12781.3 1.63E-05 20/64 R.LQGSGVTVNALHPGVAR.T sp|Q8NBN7|RDH13_HUMAN 1 1674.9166 0.62 64798 12781 3 1674.921613 559.3128 Retinol dehydrogenase 13 OS=Homo sapiens OX=9606 GN=RDH13 PE=1 SV=2 9.76 2436.1 - 293566 - - - 3.0216 - 3.337 0.498 - 478.9 1 2 0 0.0051 17 0 0 0 1.13E+07 1.81E+07 - - - 7.1352 0.9997 221125_WJC_METTL3_EV_vs_WT_F05.12783.12783.3 0.000851 Dec-56 R.IAVHPDYQGMGYGSR[166.11].A "sp|Q9H0A0|NAT10_HUMAN,tr|A0A087WV29|A0A087WV29_HUMAN" 2 1659.7703 0.6 64800 12783 3 1659.774514 554.264 RNA cytidine acetyltransferase OS=Homo sapiens OX=9606 GN=NAT10 PE=1 SV=2 6.74 2436.3 - 183464 - - - 2.5419 - 2.48 0.386 - 172.2 1 2 0 0.0042 15 0 0 0 4.76E+06 7.93E+06 - - - 5.2123 0.9996 221125_WJC_METTL3_EV_vs_WT_F05.12784.12784.2 3.84E-05 26-Sep R.GDPYPQEVSATVQK[136.11].V "sp|P22830|HEMH_HUMAN,tr|A0A499FJN5|A0A499FJN5_HUMAN,tr|K7EJX5|K7EJX5_HUMAN,tr|K7ELX4|K7ELX4_HUMAN" 4 1525.7504 2.31 64801 12784 2 1525.746741 763.8825 "Ferrochelatase, mitochondrial OS=Homo sapiens OX=9606 GN=FECH PE=1 SV=2" 4.37 2436.4 - 150448 - - - -2.3903 - 1.915 0.535 - 213.4 1 2 0 -0.0036 14 0 0 0 5.43E+06 2.35E+06 - - - 4.6218 1 221125_WJC_METTL3_EV_vs_WT_F05.12790.12790.2 1.71E-09 15/42 F.VAAAPVAAATTAAPAAAAAPAK[136.11].V "sp|P05388|RLA0_HUMAN,tr|F8VWS0|F8VWS0_HUMAN,tr|F8W1K8|F8W1K8_HUMAN" 3 1840.0298 2.09 64806 12790 2 1840.034808 921.0222 60S acidic ribosomal protein P0 OS=Homo sapiens OX=9606 GN=RPLP0 PE=1 SV=1 8.72 2437.3 - 143648 - - - 2.7228 - 3.537 0.637 - 533.3 1 1 0 0.005 22 0 0 0 8.33E+05 3.98E+05 - - - 6.8501 1 221125_WJC_METTL3_EV_vs_WT_F05.12793.12793.3 3.78E-07 16/44 K.K[136.11]QQISLATQMVR[166.11].M "sp|P48643|TCPE_HUMAN,tr|E9PCA1|E9PCA1_HUMAN,tr|B7ZAR1|B7ZAR1_HUMAN,tr|E7ENZ3|E7ENZ3_HUMAN" 4 1419.7987 0.51 64809 12793 3 1419.801087 474.2735 T-complex protein 1 subunit epsilon OS=Homo sapiens OX=9606 GN=CCT5 PE=1 SV=1 11 2437.6 - 4.37E+06 - - - 1.689 - 3.128 0.553 - 573.5 1 2 0 0.0024 12 0 0 0 1.54E+07 3.00E+07 - - - 7.8657 1 221125_WJC_METTL3_EV_vs_WT_F05.12794.12794.3 2.60E-07 15/44 K.KQQISLATQMVR.M "sp|P48643|TCPE_HUMAN,tr|E9PCA1|E9PCA1_HUMAN,tr|B7ZAR1|B7ZAR1_HUMAN,tr|E7ENZ3|E7ENZ3_HUMAN" 4 1401.7762 0.51 64810 12794 3 1401.779778 468.266 T-complex protein 1 subunit epsilon OS=Homo sapiens OX=9606 GN=CCT5 PE=1 SV=1 11 2437.6 - 2.00E+06 - - - 2.5389 - 3.219 0.505 - 541.6 1 2 0 0.0036 12 0 0 0 1.52E+07 3.00E+07 - - - 7.4098 0.9998 221125_WJC_METTL3_EV_vs_WT_F05.12795.12795.2 3.34E-07 13/22 K.EAATSELQSIQR.L sp|O15119|TBX3_HUMAN 1 1331.6681 1.04 64811 12795 2 1331.670151 666.8413 T-box transcription factor TBX3 OS=Homo sapiens OX=9606 GN=TBX3 PE=1 SV=4 4.53 2437.7 - 1.33E+06 - - - 1.5342 - 2.78 0.481 - 886.5 1 2 0 0.002 12 0 0 0 1.48E+08 1.42E+08 - - - 5.2833 0.9993 221125_WJC_METTL3_EV_vs_WT_F05.12796.12796.3 0.0402 Oct-40 R.ESVDHLTIPSR[166.11].C "sp|P41252|SYIC_HUMAN,tr|A0A804HL54|A0A804HL54_HUMAN,tr|A0A804HKU1|A0A804HKU1_HUMAN,tr|A0A804HK69|A0A804HK69_HUMAN,tr|A0A804HIV9|A0A804HIV9_HUMAN,tr|A0A804HJN6|A0A804HJN6_HUMAN,tr|A0A804HHW9|A0A804HHW9_HUMAN,tr|A0A0A0MSX9|A0A0A0MSX9_HUMAN,tr|J3KR24|J3KR24_HUMAN,tr|A0A804HJ36|A0A804HJ36_HUMAN" 10 1262.6494 0.69 64812 12796 3 1262.64843 421.8904 "Isoleucine--tRNA ligase, cytoplasmic OS=Homo sapiens OX=9606 GN=IARS1 PE=1 SV=2" 5.32 2437.8 - 1.12E+06 - - - -0.7959 - 2.217 0.245 - 152.1 1 2 0 -0.001 11 0 0 0 8.38E+06 1.21E+07 - - - 3.533 0.9998 221125_WJC_METTL3_EV_vs_WT_F05.12797.12797.2 6.49E-05 20-Nov R.QTVEADVNGLR.R sp|P08779|K1C16_HUMAN 1 1200.6099 999 64813 12797 2 1200.611693 601.3122 "Keratin, type I cytoskeletal 16 OS=Homo sapiens OX=9606 GN=KRT16 PE=1 SV=4" 4.37 2437.9 - 1.06E+06 - - - 1.5226 - 2.27 0.559 - 660.4 1 2 0 0.0018 11 0 0 0 2.08E+07 0.00E+00 - - - 5.3869 0.9586 221125_WJC_METTL3_EV_vs_WT_F05.12798.12798.3 0.247 Aug-40 R.ESVDHLTIPSR.C "sp|P41252|SYIC_HUMAN,tr|A0A804HL54|A0A804HL54_HUMAN,tr|A0A804HKU1|A0A804HKU1_HUMAN,tr|A0A804HK69|A0A804HK69_HUMAN,tr|A0A804HIV9|A0A804HIV9_HUMAN,tr|A0A804HJN6|A0A804HJN6_HUMAN,tr|A0A804HHW9|A0A804HHW9_HUMAN,tr|A0A0A0MSX9|A0A0A0MSX9_HUMAN,tr|J3KR24|J3KR24_HUMAN,tr|A0A804HJ36|A0A804HJ36_HUMAN" 10 1252.6412 0.69 64814 12798 3 1252.640501 418.5543 "Isoleucine--tRNA ligase, cytoplasmic OS=Homo sapiens OX=9606 GN=IARS1 PE=1 SV=2" 5.32 2437.9 - 996493 - - - -0.5301 - 1.612 0.096 - 105.7 1 2 0 -0.0007 11 0 0 0 8.38E+06 1.21E+07 - - - 0.9665 1 221125_WJC_METTL3_EV_vs_WT_F05.12801.12801.3 3.23E-08 16/56 R.IAVHPDYQGMGYGSR.A "sp|Q9H0A0|NAT10_HUMAN,tr|A0A087WV29|A0A087WV29_HUMAN" 2 1649.762 0.6 64817 12801 3 1649.763478 550.928 RNA cytidine acetyltransferase OS=Homo sapiens OX=9606 GN=NAT10 PE=1 SV=2 6.74 2438.2 - 604182 - - - 0.8807 - 3.081 0.638 - 309.2 1 2 0 0.0015 15 0 0 0 4.76E+06 7.98E+06 - - - 8.5889 0.9999 221125_WJC_METTL3_EV_vs_WT_F05.12802.12802.2 1.64E-09 26-Nov R.GDPYPQEVSATVQK.V "sp|P22830|HEMH_HUMAN,tr|A0A499FJN5|A0A499FJN5_HUMAN,tr|K7EJX5|K7EJX5_HUMAN,tr|K7ELX4|K7ELX4_HUMAN" 4 1517.7362 1.69 64818 12802 2 1517.736429 759.8754 "Ferrochelatase, mitochondrial OS=Homo sapiens OX=9606 GN=FECH PE=1 SV=2" 4.37 2438.4 - 313792 - - - 0.1588 - 2.103 0.5 - 333.6 1 2 0 0.0002 14 0 0 0 3.02E+06 1.78E+06 - - - 4.5994 0.9998 221125_WJC_METTL3_EV_vs_WT_F05.12805.12805.3 6.81E-05 Sep-36 R.AFESDVFHNR.T "sp|O14545|TRAD1_HUMAN,tr|F8VNX8|F8VNX8_HUMAN" 2 1220.5574 0.67 64821 12805 3 1220.559429 407.8598 TRAF-type zinc finger domain-containing protein 1 OS=Homo sapiens OX=9606 GN=TRAFD1 PE=1 SV=1 5.32 2438.7 - 238540 - - - 1.6337 - 1.995 0.414 - 76.2 1 2 0 0.002 10 0 0 0 1.19E+06 1.78E+06 - - - 5.1721 0.9887 221125_WJC_METTL3_EV_vs_WT_F05.12806.12806.2 1.73E-05 14/42 F.VAAAPVAAATTAAPAAAAAPAK.V "sp|P05388|RLA0_HUMAN,tr|F8VWS0|F8VWS0_HUMAN,tr|F8W1K8|F8W1K8_HUMAN" 3 1832.0156 2.09 64822 12806 2 1832.019252 917.0151 60S acidic ribosomal protein P0 OS=Homo sapiens OX=9606 GN=RPLP0 PE=1 SV=1 8.72 2438.9 - 231530 - - - 1.9945 - 3.52 0.483 - 470.5 1 1 0 0.0037 22 0 0 0 8.33E+05 3.98E+05 - - - 5.7013 0.9979 221125_WJC_METTL3_EV_vs_WT_F05.12807.12807.3 0.112 Oct-36 K.GK[136.11]PVLELPER[166.11].K "sp|Q14527|HLTF_HUMAN,tr|H7C5K0|H7C5K0_HUMAN,tr|A0A0C4DGA6|A0A0C4DGA6_HUMAN" 3 1154.6778 0.29 64823 12807 3 1154.677887 385.8999 Helicase-like transcription factor OS=Homo sapiens OX=9606 GN=HLTF PE=1 SV=2 6.14 2439 - 277203 - - - 0.0502 - 1.673 0.248 - 105.7 1 2 0 0.0001 10 0 0 0 1.98E+06 6.87E+06 - - - 2.8078 1 221125_WJC_METTL3_EV_vs_WT_F05.12811.12811.3 3.23E-06 14/48 R.LEEYLTQQEIGKK.A sp|Q86XL3|ANKL2_HUMAN 1 1577.8301 2.65 64826 12811 3 1577.829682 526.9506 Ankyrin repeat and LEM domain-containing protein 2 OS=Homo sapiens OX=9606 GN=ANKLE2 PE=1 SV=4 4.79 2439.5 - 1.30E+06 - - - -0.2573 - 2.309 0.52 - 255.6 1 2 0 -0.0004 13 0 0 0 1.02E+07 3.85E+06 - - - 6.6062 1 221125_WJC_METTL3_EV_vs_WT_F05.12813.12813.2 8.72E-08 13/22 R.SSTDSLPGPISR[166.11].Q sp|Q9HCD5|NCOA5_HUMAN 1 1225.6178 2.29 64828 12813 2 1225.618066 613.8162 Nuclear receptor coactivator 5 OS=Homo sapiens OX=9606 GN=NCOA5 PE=1 SV=2 5.55 2439.7 - 7.85E+06 - - - 0.2162 - 2.686 0.567 - 361.1 1 2 0 0.0003 12 0 0 0 3.31E+08 1.44E+08 - - - 5.8285 1 221125_WJC_METTL3_EV_vs_WT_F05.12815.12815.3 3.28E-09 19/64 K.VYVGNLGTGAGKGELER.A "sp|Q16629|SRSF7_HUMAN,tr|C9JAB2|C9JAB2_HUMAN,tr|A0A0B4J1Z1|A0A0B4J1Z1_HUMAN" 3 1718.8951 1.48 64830 12815 3 1718.896813 573.9723 Serine\arginine-rich splicing factor 7 OS=Homo sapiens OX=9606 GN=SRSF7 PE=1 SV=1 6.11 2439.8 - 1.52E+06 - - - 0.9686 - 3.603 0.585 - 366.1 1 2 1 0.0017 17 0 0 0 1.65E+08 1.12E+08 - - - 8.2998 0.9999 221125_WJC_METTL3_EV_vs_WT_F05.12816.12816.3 4.71E-11 22/64 K.VYVGNLGTGAGK[136.11]GELER[166.11].A "sp|Q16629|SRSF7_HUMAN,tr|C9JAB2|C9JAB2_HUMAN,tr|A0A0B4J1Z1|A0A0B4J1Z1_HUMAN" 3 1736.9176 1.48 64831 12816 3 1736.917731 579.9798 Serine\arginine-rich splicing factor 7 OS=Homo sapiens OX=9606 GN=SRSF7 PE=1 SV=1 6.11 2439.9 - 1.47E+06 - - - 0.0651 - 3.993 0.543 - 494.1 1 2 1 0.0001 17 0 0 0 1.65E+08 1.12E+08 - - - 8.0917 1 221125_WJC_METTL3_EV_vs_WT_F05.12817.12817.3 1.63E-08 18/56 R.GGGGNFGPGPGSNFR.G "sp|P22626|ROA2_HUMAN,tr|A0A024RA28|A0A024RA28_HUMAN,tr|A0A7I2V4N1|A0A7I2V4N1_HUMAN,tr|A0A7I2V4I6|A0A7I2V4I6_HUMAN,tr|A0A7I2V4S4|A0A7I2V4S4_HUMAN,tr|A0A7I2V323|A0A7I2V323_HUMAN,tr|A0A7I2V3P1|A0A7I2V3P1_HUMAN,tr|A0A7I2V3P7|A0A7I2V3P7_HUMAN" 8 1376.6222 1.94 64832 12817 3 1376.621248 459.8813 Heterogeneous nuclear ribonucleoproteins A2\B1 OS=Homo sapiens OX=9606 GN=HNRNPA2B1 PE=1 SV=2 9.75 2439.9 - 989254 - - - -0.6632 - 2.883 0.618 - 480.3 1 2 0 -0.0009 15 0 0 0 5.67E+07 2.93E+07 - - - 8.1927 0.9954 221125_WJC_METTL3_EV_vs_WT_F05.12818.12818.3 0.136 14/48 R.KPYPDDENLVEVK.F "sp|A6NEC2|PSAL_HUMAN,sp|P55786|PSA_HUMAN,tr|A0A7I2V3W8|A0A7I2V3W8_HUMAN,tr|E9PPZ2|E9PPZ2_HUMAN,tr|A0A7I2V389|A0A7I2V389_HUMAN,tr|E9PLK3|E9PLK3_HUMAN,tr|A0A7I2V604|A0A7I2V604_HUMAN" 7 1544.7722 3.97 64833 12818 3 1544.77148 515.9314 Puromycin-sensitive aminopeptidase-like protein OS=Homo sapiens OX=9606 GN=NPEPPSL1 PE=2 SV=3 4.32 2440 - 781319 - - - -0.4913 - 1.756 0.199 - 219 1 2 0 -0.0008 13 0 0 0 5.50E+06 1.38E+06 - - - 2.285 0.9957 221125_WJC_METTL3_EV_vs_WT_F05.12819.12819.3 3.25E-05 13/52 G.DGVGGDPAVALPHR[166.11].R sp|P49257|LMAN1_HUMAN 1 1369.6978 2.16 64834 12819 3 1369.696747 457.5732 Protein ERGIC-53 OS=Homo sapiens OX=9606 GN=LMAN1 PE=1 SV=2 5.21 2440.1 - 545164 - - - -0.7556 - 2.395 0.473 - 324.8 1 1 0 -0.001 14 0 0 0 2.83E+07 1.31E+07 - - - 6.1342 0.9023 221125_WJC_METTL3_EV_vs_WT_F05.12820.12820.3 0.0283 Jul-36 L.DTYNC[160.03]DLHFK.L "sp|Q00839|HNRPU_HUMAN,sp|Q9BUJ2|HNRL1_HUMAN,tr|Q5RI18|Q5RI18_HUMAN,tr|M0R0K8|M0R0K8_HUMAN,tr|A0A1W2PP35|A0A1W2PP35_HUMAN,tr|A0A1W2PPS1|A0A1W2PPS1_HUMAN,tr|M0QYZ0|M0QYZ0_HUMAN,tr|A0A0A0MRA5|A0A0A0MRA5_HUMAN,tr|M0R3F1|M0R3F1_HUMAN,tr|B7Z4B8|B7Z4B8_HUMAN,tr|A0A1W2PRI6|A0A1W2PRI6_HUMAN,tr|M0QYI8|M0QYI8_HUMAN,tr|M0QYM5|M0QYM5_HUMAN" 13 1311.5554 1.06 64835 12820 3 1311.556058 438.1924 Heterogeneous nuclear ribonucleoprotein U OS=Homo sapiens OX=9606 GN=HNRNPU PE=1 SV=6 5.21 2440.3 - 450117 - - - 0.5116 - 1.197 0.379 - 45.6 1 1 0 0.0007 10 0 0 0 2.02E+06 1.90E+06 - - - 3.2904 0.9879 221125_WJC_METTL3_EV_vs_WT_F05.12821.12821.3 0.00851 Sep-36 L.DTYNC[160.03]DLHFK[136.11].L "sp|Q00839|HNRPU_HUMAN,sp|Q9BUJ2|HNRL1_HUMAN,tr|Q5RI18|Q5RI18_HUMAN,tr|M0R0K8|M0R0K8_HUMAN,tr|A0A1W2PP35|A0A1W2PP35_HUMAN,tr|A0A1W2PPS1|A0A1W2PPS1_HUMAN,tr|M0QYZ0|M0QYZ0_HUMAN,tr|A0A0A0MRA5|A0A0A0MRA5_HUMAN,tr|M0R3F1|M0R3F1_HUMAN,tr|B7Z4B8|B7Z4B8_HUMAN,tr|A0A1W2PRI6|A0A1W2PRI6_HUMAN,tr|M0QYI8|M0QYI8_HUMAN,tr|M0QYM5|M0QYM5_HUMAN" 13 1319.5696 1.06 64836 12821 3 1319.57072 440.8638 Heterogeneous nuclear ribonucleoprotein U OS=Homo sapiens OX=9606 GN=HNRNPU PE=1 SV=6 5.21 2440.4 - 435225 - - - 0.8586 - 1.68 0.451 - 89.3 1 1 0 0.0011 10 0 0 0 2.02E+06 1.90E+06 - - - 5.083 0.9674 221125_WJC_METTL3_EV_vs_WT_F05.12823.12823.2 0.343 30-Jul R.TGQPSAPGDTSVNGPV.- "sp|Q5H9R7|PP6R3_HUMAN,tr|H7BXH2|H7BXH2_HUMAN,tr|H0YDK9|H0YDK9_HUMAN,tr|E9PQP7|E9PQP7_HUMAN,tr|H0YEN2|H0YEN2_HUMAN,tr|E9PKF6|E9PKF6_HUMAN" 6 1482.6951 - 64838 12823 2 1482.696862 742.3548 Serine\threonine-protein phosphatase 6 regulatory subunit 3 OS=Homo sapiens OX=9606 GN=PPP6R3 PE=1 SV=2 3.8 2440.6 - 220039 - - - 1.2214 - 1.285 0.058 - 63.7 1 2 0 0.0018 16 0 0 0 - - - - - 0.0853 1 221125_WJC_METTL3_EV_vs_WT_F05.12824.12824.2 6.57E-09 16/34 R.LEEDDGDVAMSDAQDGPR.V "sp|Q9UBU9|NXF1_HUMAN,tr|E9PQA4|E9PQA4_HUMAN,tr|E9PIN3|E9PIN3_HUMAN" 3 1918.7851 1.46 64839 12824 2 1918.785054 960.3998 Nuclear RNA export factor 1 OS=Homo sapiens OX=9606 GN=NXF1 PE=1 SV=1 3.57 2440.8 - 183846 - - - -0.0057 - 3.503 0.767 - 692.3 1 2 0 0 18 0 0 0 6.46E+06 4.41E+06 - - - 7.7881 0.9933 221125_WJC_METTL3_EV_vs_WT_F05.12825.12825.3 0.0185 Jul-36 R.SC[160.03]HTAVELFK.N sp|Q9UBV2|SE1L1_HUMAN 1 1190.5754 -1 64840 12825 3 1190.575665 397.8657 Protein sel-1 homolog 1 OS=Homo sapiens OX=9606 GN=SEL1L PE=1 SV=3 6.46 2440.9 - 156363 - - - 0.2276 - 1.211 0.265 - 50.1 1 2 0 0.0003 10 0 0 0 0.00E+00 0.00E+00 - - - 2.0535 0.9979 221125_WJC_METTL3_EV_vs_WT_F05.12828.12828.3 0.000192 Nov-40 R.EFTGAHIDIDK.Q "sp|O75179|ANR17_HUMAN,tr|H0YM23|H0YM23_HUMAN" 2 1244.6037 6.67 64841 12828 3 1244.599919 415.8752 Ankyrin repeat domain-containing protein 17 OS=Homo sapiens OX=9606 GN=ANKRD17 PE=1 SV=3 4.54 2441.3 - 1.52E+06 - - - -3.0516 - 2.057 0.285 - 186.2 1 2 0 -0.0038 11 0 0 0 5.76E+07 8.64E+06 - - - 3.7654 1 221125_WJC_METTL3_EV_vs_WT_F05.12829.12829.3 1.80E-07 20/56 R.GGGGNFGPGPGSNFR[166.11].G "sp|P22626|ROA2_HUMAN,tr|A0A024RA28|A0A024RA28_HUMAN,tr|A0A7I2V4N1|A0A7I2V4N1_HUMAN,tr|A0A7I2V4I6|A0A7I2V4I6_HUMAN,tr|A0A7I2V4S4|A0A7I2V4S4_HUMAN,tr|A0A7I2V323|A0A7I2V323_HUMAN,tr|A0A7I2V3P1|A0A7I2V3P1_HUMAN,tr|A0A7I2V3P7|A0A7I2V3P7_HUMAN" 8 1386.6304 1.94 64842 12829 3 1386.630177 463.2174 Heterogeneous nuclear ribonucleoproteins A2\B1 OS=Homo sapiens OX=9606 GN=HNRNPA2B1 PE=1 SV=2 9.75 2441.4 - 877453 - - - -0.1832 - 3.246 0.571 - 699.2 1 2 0 -0.0003 15 0 0 0 5.67E+07 2.93E+07 - - - 7.9783 1 221125_WJC_METTL3_EV_vs_WT_F05.12832.12832.2 1.06E-09 16/34 R.LEEDDGDVAMSDAQDGPR[166.11].V "sp|Q9UBU9|NXF1_HUMAN,tr|E9PQA4|E9PQA4_HUMAN,tr|E9PIN3|E9PIN3_HUMAN" 3 1928.7933 1.46 64845 12832 2 1928.789556 965.4039 Nuclear RNA export factor 1 OS=Homo sapiens OX=9606 GN=NXF1 PE=1 SV=1 3.57 2441.8 - 311604 - - - -1.9593 - 3.254 0.743 - 569.1 1 2 0 -0.0038 18 0 0 0 6.46E+06 4.41E+06 - - - 7.4284 0.9824 221125_WJC_METTL3_EV_vs_WT_F05.12836.12836.3 0.0046 Dec-48 R.LKELESQVSGLEK.E "sp|Q9P2E9|RRBP1_HUMAN,tr|A0A087WVV2|A0A087WVV2_HUMAN,tr|F8W7S5|F8W7S5_HUMAN" 3 1458.793 1.42 64847 12836 3 1458.789248 487.2716 Ribosome-binding protein 1 OS=Homo sapiens OX=9606 GN=RRBP1 PE=1 SV=5 4.79 2442.3 - 3.60E+06 - - - -2.5542 - 2.011 0.235 - 164.5 1 2 1 -0.0037 13 0 0 0 7.79E+07 5.50E+07 - - - 3.0532 1 221125_WJC_METTL3_EV_vs_WT_F05.12838.12838.2 1.42E-05 22-Nov R.AQVQEFC[160.03]DYGTK[136.11].E "sp|Q86U44|MTA70_HUMAN,tr|H0YFV6|H0YFV6_HUMAN" 2 1452.6435 0.04 64849 12838 2 1452.642381 727.329 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 4.37 2442.5 - 1.08E+09 - - - -0.7566 - 2.527 0.576 - 361.9 1 2 0 -0.0011 12 0 0 0 6.82E+09 1.91E+11 - - - 5.7342 1 221125_WJC_METTL3_EV_vs_WT_F05.12839.12839.3 1.20E-05 Nov-44 R.AQVQEFC[160.03]DYGTK[136.11].E "sp|Q86U44|MTA70_HUMAN,tr|H0YFV6|H0YFV6_HUMAN" 2 1452.6435 0.02 64850 12839 3 1452.639989 485.2218 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 4.37 2442.5 - 3.59E+07 - - - -2.4032 - 2.255 0.611 - 138.1 1 2 0 -0.0035 12 0 0 0 1.02E+08 6.05E+09 - - - 7.605 0.983 221125_WJC_METTL3_EV_vs_WT_F05.12843.12843.2 4.35E-05 18-Dec Q.VQEFC[160.03]DYGTK[136.11].E "sp|Q86U44|MTA70_HUMAN,tr|H0YFV6|H0YFV6_HUMAN" 2 1253.5478 0.001 64854 12843 2 1253.544459 627.7812 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 4.37 2443 - 572917 - - - -2.6565 - 2.343 0.577 - 663.2 1 1 0 -0.0033 10 0 0 0 0.00E+00 7.73E+07 - - - 5.6783 1 221125_WJC_METTL3_EV_vs_WT_F05.12852.12852.2 4.45E-09 15/28 K.LTSSAEDEVETTYSR.F "sp|P42694|HELZ_HUMAN,tr|J3QS41|J3QS41_HUMAN" 2 1686.7584 4.68 64859 12852 2 1686.753785 844.3865 Probable helicase with zinc finger domain OS=Homo sapiens OX=9606 GN=HELZ PE=1 SV=2 4 2444.1 - 1.38E+06 - - - -2.7591 - 3.121 0.571 - 894.5 1 2 0 -0.0047 15 0 0 0 1.33E+08 2.84E+07 - - - 6.0551 1 221125_WJC_METTL3_EV_vs_WT_F05.12879.12879.2 4.05E-08 22-Dec R.AQVQEFC[160.03]DYGTK.E "sp|Q86U44|MTA70_HUMAN,tr|H0YFV6|H0YFV6_HUMAN" 2 1444.6293 0.04 64866 12879 2 1444.626939 723.3219 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 4.37 2448 - 1.01E+08 - - - -1.6205 - 2.531 0.658 - 458.7 1 2 0 -0.0023 12 0 0 0 6.81E+09 1.91E+11 - - - 6.3436 0.9999 221125_WJC_METTL3_EV_vs_WT_F05.12886.12886.3 5.45E-07 16/48 R.VAIHYINPPNPAK.D "sp|P78406|RAE1L_HUMAN,tr|E9PQ57|E9PQ57_HUMAN" 2 1432.7827 2.11 64868 12886 3 1432.777626 478.6015 mRNA export factor OS=Homo sapiens OX=9606 GN=RAE1 PE=1 SV=1 8.57 2448.9 - 7.52E+06 - - - -3.5302 - 3.05 0.527 - 458.7 1 2 0 -0.0051 13 0 0 0 4.79E+08 2.27E+08 - - - 7.4376 0.9998 221125_WJC_METTL3_EV_vs_WT_F05.12887.12887.3 6.26E-06 15/44 K.DLHDANTDLIGR[166.11].H "sp|P53985|MOT1_HUMAN,tr|Q5T8R3|Q5T8R3_HUMAN,tr|Q5T8R5|Q5T8R5_HUMAN" 3 1348.6611 1.18 64869 12887 3 1348.65589 450.561 Monocarboxylate transporter 1 OS=Homo sapiens OX=9606 GN=SLC16A1 PE=1 SV=3 4.41 2449.1 - 3.60E+06 - - - -3.8349 - 2.47 0.504 - 297.5 1 2 0 -0.0052 12 0 0 0 1.34E+08 1.13E+08 - - - 6.664 1 221125_WJC_METTL3_EV_vs_WT_F05.12891.12891.2 3.69E-06 24-Dec R.DQTPDENEEVIVR.L "sp|Q9Y6M1|IF2B2_HUMAN,tr|F8W930|F8W930_HUMAN" 2 1542.7162 1.81 64870 12891 2 1542.712642 772.3654 Insulin-like growth factor 2 mRNA-binding protein 2 OS=Homo sapiens OX=9606 GN=IGF2BP2 PE=1 SV=2 3.83 2449.6 - 5.26E+06 - - - -2.294 - 2.664 0.595 - 507.1 1 2 0 -0.0035 13 0 0 0 1.55E+08 8.58E+07 - - - 5.9493 0.9999 221125_WJC_METTL3_EV_vs_WT_F05.12893.12893.3 0.000598 Nov-44 K.DLHDANTDLIGR.H "sp|P53985|MOT1_HUMAN,tr|Q5T8R3|Q5T8R3_HUMAN,tr|Q5T8R5|Q5T8R5_HUMAN" 3 1338.6528 1.21 64871 12893 3 1338.64937 447.2249 Monocarboxylate transporter 1 OS=Homo sapiens OX=9606 GN=SLC16A1 PE=1 SV=3 4.41 2449.8 - 1.68E+06 - - - -2.5563 - 2.178 0.515 - 196.2 1 2 0 -0.0034 12 0 0 0 1.37E+08 1.13E+08 - - - 6.4384 0.9966 221125_WJC_METTL3_EV_vs_WT_F05.12895.12895.3 0.205 18/52 R.FAQHGTFEYEYSQR[166.11].W "sp|P23246|SFPQ_HUMAN,tr|H0Y9K7|H0Y9K7_HUMAN" 2 1771.783 0.92 64872 12895 3 1771.780984 591.6016 "Splicing factor, proline- and glutamine-rich OS=Homo sapiens OX=9606 GN=SFPQ PE=1 SV=2" 5.4 2450 - 2.24E+06 - - - -1.1198 - 1.539 0.254 - 127.8 1 2 0 -0.002 14 0 0 0 4.90E+07 5.30E+07 - - - 2.517 0.9981 221125_WJC_METTL3_EV_vs_WT_F05.12897.12897.2 1.30E-05 24-Dec R.DQTPDENEEVIVR[166.11].L "sp|Q9Y6M1|IF2B2_HUMAN,tr|F8W930|F8W930_HUMAN" 2 1552.7245 1.81 64873 12897 2 1552.716321 777.3695 Insulin-like growth factor 2 mRNA-binding protein 2 OS=Homo sapiens OX=9606 GN=IGF2BP2 PE=1 SV=2 3.83 2450.3 - 1.66E+06 - - - -5.236 - 2.498 0.581 - 514.1 1 2 0 -0.0081 13 0 0 0 1.55E+08 8.58E+07 - - - 5.6793 1 221125_WJC_METTL3_EV_vs_WT_F05.12901.12901.3 2.02E-08 22/60 R.AASIFGGAKPVDTAAR.E "sp|P23588|IF4B_HUMAN,tr|E7EX17|E7EX17_HUMAN,tr|F8VX11|F8VX11_HUMAN" 3 1530.8154 2.44 64875 12901 3 1530.811771 511.2791 Eukaryotic translation initiation factor 4B OS=Homo sapiens OX=9606 GN=EIF4B PE=1 SV=2 8.79 2450.8 - 2.09E+06 - - - -2.3974 - 3.308 0.518 - 566.4 1 2 0 -0.0037 16 0 0 0 3.42E+08 1.40E+08 - - - 7.3838 0.9536 221125_WJC_METTL3_EV_vs_WT_F05.12903.12903.3 0.0903 13/32 K.EKIYVLLRR.Q sp|P84090|ERH_HUMAN 1 1188.7343 2.61 64877 12903 3 1188.729821 397.252 Enhancer of rudimentary homolog OS=Homo sapiens OX=9606 GN=ERH PE=1 SV=1 9.99 2451 - 2.42E+06 - - - -3.7494 - 1.645 0.263 - 284 1 2 1 -0.0045 9 0 0 0 7.44E+07 2.85E+07 - - - 2.971 0.9999 221125_WJC_METTL3_EV_vs_WT_F05.12904.12904.3 8.32E-05 15/32 R.HLDRPVFLR.F "sp|Q6P1J9|CDC73_HUMAN,tr|A0A1B0GUB2|A0A1B0GUB2_HUMAN" 2 1151.6564 1.4 64878 12904 3 1151.654642 384.8927 Parafibromin OS=Homo sapiens OX=9606 GN=CDC73 PE=1 SV=1 9.61 2451.1 - 1.87E+06 - - - -1.4935 - 2.077 0.448 - 318.4 1 2 0 -0.0017 9 0 0 0 8.10E+07 5.78E+07 - - - 5.7371 0.9917 221125_WJC_METTL3_EV_vs_WT_F05.12908.12908.3 0.028 15/40 R.YYTVFDRDNNR.V "sp|P07339|CATD_HUMAN,tr|A0A1B0GW44|A0A1B0GW44_HUMAN,tr|A0A1B0GVD5|A0A1B0GVD5_HUMAN,tr|A0A1B0GV23|A0A1B0GV23_HUMAN,tr|C9JH19|C9JH19_HUMAN,tr|H7C469|H7C469_HUMAN,tr|A0A1B0GWE8|A0A1B0GWE8_HUMAN,tr|A0A1B0GVP3|A0A1B0GVP3_HUMAN,tr|F8W787|F8W787_HUMAN" 9 1461.6637 26.68 64879 12908 3 1461.65779 488.2285 Cathepsin D OS=Homo sapiens OX=9606 GN=CTSD PE=1 SV=1 5.96 2451.7 - 1.74E+06 - - - -4.0372 - 1.868 0.372 - 199 1 2 1 -0.0059 11 0 0 0 7.22E+07 2.71E+06 - - - 4.4609 0.9999 221125_WJC_METTL3_EV_vs_WT_F05.12914.12914.2 0.000171 15/26 R.EQQIVIQSSGGLSK[136.11].D "sp|P38646|GRP75_HUMAN,tr|A0A7I2V2S7|A0A7I2V2S7_HUMAN,tr|A0A7I2V2G2|A0A7I2V2G2_HUMAN,tr|H0Y8S0|H0Y8S0_HUMAN,tr|A0A7I2V3F7|A0A7I2V3F7_HUMAN,tr|A0A7I2YQB2|A0A7I2YQB2_HUMAN,tr|D6RCD7|D6RCD7_HUMAN" 7 1480.7977 0.49 64882 12914 2 1480.797498 741.4061 "Stress-70 protein, mitochondrial OS=Homo sapiens OX=9606 GN=HSPA9 PE=1 SV=2" 6.1 2452.4 - 4.53E+06 - - - -0.1175 - 2.703 0.537 - 637.7 1 2 0 -0.0002 14 0 0 0 6.48E+07 1.32E+08 - - - 5.5025 0.9987 221125_WJC_METTL3_EV_vs_WT_F05.12915.12915.2 0.0215 16-Aug K.DQIIDSLKR.G "sp|Q6P3W7|SCYL2_HUMAN,tr|F8VSC5|F8VSC5_HUMAN,tr|A0A0U1RQQ9|A0A0U1RQQ9_HUMAN" 3 1086.6033 2.39 64883 12915 2 1086.601104 544.3089 SCY1-like protein 2 OS=Homo sapiens OX=9606 GN=SCYL2 PE=1 SV=1 5.96 2452.5 - 2.21E+06 - - - -2.0421 - 1.742 0.302 - 256.5 1 2 0 -0.0022 9 0 0 0 5.47E+07 2.29E+07 - - - 2.8766 0.9999 221125_WJC_METTL3_EV_vs_WT_F05.12916.12916.3 0.151 21/60 R.AASIFGGAK[136.11]PVDTAAR[166.11].E "sp|P23588|IF4B_HUMAN,tr|E7EX17|E7EX17_HUMAN,tr|F8VX11|F8VX11_HUMAN" 3 1548.8379 2.44 64884 12916 3 1548.832476 517.2866 Eukaryotic translation initiation factor 4B OS=Homo sapiens OX=9606 GN=EIF4B PE=1 SV=2 8.79 2452.6 - 2.22E+06 - - - -3.5091 - 3.514 0.483 - 492.1 1 2 0 -0.0054 16 0 0 0 3.41E+08 1.40E+08 - - - 7.1481 0.9998 221125_WJC_METTL3_EV_vs_WT_F05.12917.12917.2 1.92E-05 17/30 R.AASIFGGAKPVDTAAR.E "sp|P23588|IF4B_HUMAN,tr|E7EX17|E7EX17_HUMAN,tr|F8VX11|F8VX11_HUMAN" 3 1530.8154 3.09 64885 12917 2 1530.81204 766.415 Eukaryotic translation initiation factor 4B OS=Homo sapiens OX=9606 GN=EIF4B PE=1 SV=2 8.79 2452.8 - 1.19E+06 - - - -2.2217 - 2.636 0.543 - 843.2 1 2 0 -0.0034 16 0 0 0 4.32E+07 1.40E+07 - - - 5.4335 1 221125_WJC_METTL3_EV_vs_WT_F05.12920.12920.3 7.59E-07 17/52 R.FAQHGTFEYEYSQR.W "sp|P23246|SFPQ_HUMAN,tr|H0Y9K7|H0Y9K7_HUMAN" 2 1761.7747 0.92 64886 12920 3 1761.771757 588.2655 "Splicing factor, proline- and glutamine-rich OS=Homo sapiens OX=9606 GN=SFPQ PE=1 SV=2" 5.4 2453.2 - 2.17E+06 - - - -1.6693 - 2.778 0.613 - 361.7 1 2 0 -0.0029 14 0 0 0 4.87E+07 5.30E+07 - - - 8.0888 0.9995 221125_WJC_METTL3_EV_vs_WT_F05.12921.12921.2 0.000232 15/26 K.GEATVSFDDPPSAK.A "sp|P35637|FUS_HUMAN,sp|Q92804|RBP56_HUMAN,tr|H3BPE7|H3BPE7_HUMAN,tr|A0A075B7D9|A0A075B7D9_HUMAN" 4 1419.6518 1.08 64887 12921 2 1419.64711 710.8332 RNA-binding protein FUS OS=Homo sapiens OX=9606 GN=FUS PE=1 SV=1 4.03 2453.3 - 2.55E+06 - - - -3.2959 - 2.76 0.536 - 457.4 1 2 0 -0.0047 14 0 0 0 1.18E+08 1.09E+08 - - - 5.5461 0.9934 221125_WJC_METTL3_EV_vs_WT_F05.12922.12922.2 0.114 16-Aug K.DQIIDSLK[136.11]R[166.11].G "sp|Q6P3W7|SCYL2_HUMAN,tr|F8VSC5|F8VSC5_HUMAN,tr|A0A0U1RQQ9|A0A0U1RQQ9_HUMAN" 3 1104.6258 2.39 64888 12922 2 1104.621798 553.3202 SCY1-like protein 2 OS=Homo sapiens OX=9606 GN=SCYL2 PE=1 SV=1 5.96 2453.4 - 1.51E+06 - - - -3.6166 - 1.814 0.225 - 302.6 1 2 0 -0.004 9 0 0 0 5.47E+07 2.29E+07 - - - 2.4245 1 221125_WJC_METTL3_EV_vs_WT_F05.12923.12923.2 8.10E-08 17/22 K.DLHDANTDLIGR.H "sp|P53985|MOT1_HUMAN,tr|Q5T8R3|Q5T8R3_HUMAN,tr|Q5T8R5|Q5T8R5_HUMAN" 3 1338.6528 0.89 64889 12923 2 1338.649644 670.3337 Monocarboxylate transporter 1 OS=Homo sapiens OX=9606 GN=SLC16A1 PE=1 SV=3 4.41 2453.6 - 1.35E+06 - - - -2.3516 - 2.583 0.609 - 947.5 1 2 0 -0.0031 12 0 0 0 2.94E+07 3.31E+07 - - - 6.0349 1 221125_WJC_METTL3_EV_vs_WT_F05.12925.12925.2 2.38E-06 15/26 K.GEATVSFDDPPSAK[136.11].A "sp|P35637|FUS_HUMAN,sp|Q92804|RBP56_HUMAN,tr|H3BPE7|H3BPE7_HUMAN,tr|A0A075B7D9|A0A075B7D9_HUMAN" 4 1427.666 1.08 64891 12925 2 1427.665939 714.8403 RNA-binding protein FUS OS=Homo sapiens OX=9606 GN=FUS PE=1 SV=1 4.03 2453.8 - 1.24E+06 - - - -0.035 - 2.743 0.573 - 511.5 1 2 0 -0.0001 14 0 0 0 1.53E+08 1.41E+08 - - - 5.8053 0.9985 221125_WJC_METTL3_EV_vs_WT_F05.12929.12929.3 0.00561 Aug-32 R.EWQHEEFYR.Y "sp|Q12931|TRAP1_HUMAN,tr|I3L0K7|I3L0K7_HUMAN,tr|I3L239|I3L239_HUMAN" 3 1322.568 1.84 64892 12929 3 1322.563345 441.8633 "Heat shock protein 75 kDa, mitochondrial OS=Homo sapiens OX=9606 GN=TRAP1 PE=1 SV=3" 4.75 2454.4 - 1.81E+06 - - - -3.5197 - 1.701 0.371 - 148.5 1 2 0 -0.0047 9 0 0 0 2.70E+07 1.47E+07 - - - 4.276 0.9998 221125_WJC_METTL3_EV_vs_WT_F05.12930.12930.2 0.000647 14/24 K.SSVNC[160.03]PFSSQDMK[136.11].Y sp|Q08211|DHX9_HUMAN 1 1493.637 1.02 64893 12930 2 1493.634421 747.8258 ATP-dependent RNA helicase A OS=Homo sapiens OX=9606 GN=DHX9 PE=1 SV=4 5.55 2454.5 - 1.70E+06 - - - -1.736 - 2.545 0.485 - 687.8 1 2 0 -0.0026 13 0 0 0 2.65E+07 2.60E+07 - - - 5.0199 0.9999 221125_WJC_METTL3_EV_vs_WT_F05.12935.12935.3 6.15E-08 17/48 R.VAIHYINPPNPAK[136.11].D "sp|P78406|RAE1L_HUMAN,tr|E9PQ57|E9PQ57_HUMAN" 2 1440.7969 2.11 64896 12935 3 1440.793116 481.2729 mRNA export factor OS=Homo sapiens OX=9606 GN=RAE1 PE=1 SV=1 8.57 2455 - 3.37E+06 - - - -2.6152 - 3.004 0.411 - 551.5 1 2 0 -0.0038 13 0 0 0 4.79E+08 2.26E+08 - - - 6.1035 1 221125_WJC_METTL3_EV_vs_WT_F05.12936.12936.2 1.33E-05 13/20 R.HETLTSLNLEK[136.11].K "sp|Q96A26|F162A_HUMAN,tr|F8W7Q4|F8W7Q4_HUMAN" 2 1291.6863 1.07 64897 12936 2 1291.684186 646.8504 Protein FAM162A OS=Homo sapiens OX=9606 GN=FAM162A PE=1 SV=2 5.4 2455.1 - 933679 - - - -1.6606 - 3.109 0.526 - 403.4 1 2 0 -0.0021 11 0 0 0 1.51E+07 1.41E+07 - - - 5.9939 0.8861 221125_WJC_METTL3_EV_vs_WT_F05.12937.12937.3 0.0427 Dec-32 K.EK[136.11]IYVLLR[166.11]R[166.11].Q sp|P84090|ERH_HUMAN 1 1216.765 2.72 64898 12937 3 1216.760592 406.5956 Enhancer of rudimentary homolog OS=Homo sapiens OX=9606 GN=ERH PE=1 SV=1 9.99 2455.3 - 678799 - - - -3.6375 - 1.791 0.178 - 200.9 1 2 1 -0.0044 9 0 0 0 7.42E+07 2.73E+07 - - - 2.2797 0.9996 221125_WJC_METTL3_EV_vs_WT_F05.12940.12940.2 0.00143 30-Dec R.AASIFGGAK[136.11]PVDTAAR[166.11].E "sp|P23588|IF4B_HUMAN,tr|E7EX17|E7EX17_HUMAN,tr|F8VX11|F8VX11_HUMAN" 3 1548.8379 3.09 64899 12940 2 1548.833255 775.4262 Eukaryotic translation initiation factor 4B OS=Homo sapiens OX=9606 GN=EIF4B PE=1 SV=2 8.79 2455.7 - 1.07E+06 - - - -3.0061 - 2.702 0.549 - 353.6 1 2 0 -0.0047 16 0 0 0 4.32E+07 1.40E+07 - - - 5.5382 1 221125_WJC_METTL3_EV_vs_WT_F05.12941.12941.2 8.95E-06 16/20 R.HETLTSLNLEK.K "sp|Q96A26|F162A_HUMAN,tr|F8W7Q4|F8W7Q4_HUMAN" 2 1283.6721 1.07 64900 12941 2 1283.667881 642.8433 Protein FAM162A OS=Homo sapiens OX=9606 GN=FAM162A PE=1 SV=2 5.4 2455.8 - 1.04E+06 - - - -3.3108 - 3.159 0.526 - 680.6 1 2 0 -0.0043 11 0 0 0 1.51E+07 1.41E+07 - - - 6.0364 1 221125_WJC_METTL3_EV_vs_WT_F05.12942.12942.2 8.95E-05 14/26 R.SSGPYGGGGQYFAK[136.11].P "sp|Q32P51|RA1L2_HUMAN,sp|P09651|ROA1_HUMAN,tr|A0A7I2YQX9|A0A7I2YQX9_HUMAN,tr|A0A7I2V5N7|A0A7I2V5N7_HUMAN,tr|A0A7I2V661|A0A7I2V661_HUMAN,tr|A0A7I2V520|A0A7I2V520_HUMAN,tr|A0A7I2V2F1|A0A7I2V2F1_HUMAN,tr|A0A7I2V497|A0A7I2V497_HUMAN,tr|A0A7I2V3K5|A0A7I2V3K5_HUMAN,tr|A0A7I2V2M7|A0A7I2V2M7_HUMAN,tr|A0A7I2V4P7|A0A7I2V4P7_HUMAN,tr|A0A7I2V5P1|A0A7I2V5P1_HUMAN,tr|A0A7I2V334|A0A7I2V334_HUMAN,tr|A0A7I2V4E2|A0A7I2V4E2_HUMAN,tr|A0A7I2V4F8|A0A7I2V4F8_HUMAN,tr|A0A7I2V3R8|A0A7I2V3R8_HUMAN,tr|F8W6I7|F8W6I7_HUMAN,tr|A0A7I2V666|A0A7I2V666_HUMAN,tr|A0A7I2V2Q7|A0A7I2V2Q7_HUMAN,tr|A0A7I2V459|A0A7I2V459_HUMAN,tr|A0A7I2YQY2|A0A7I2YQY2_HUMAN,tr|H0YH80|H0YH80_HUMAN,tr|A0A7I2V3W0|A0A7I2V3W0_HUMAN,tr|A0A7I2V3U8|A0A7I2V3U8_HUMAN,tr|A0A7I2V2R4|A0A7I2V2R4_HUMAN,tr|A0A7I2V2X1|A0A7I2V2X1_HUMAN,tr|A0A7I2V453|A0A7I2V453_HUMAN,tr|A0A7I2V360|A0A7I2V360_HUMAN" 28 1382.6346 12.06 64901 12942 2 1382.632931 692.3246 Heterogeneous nuclear ribonucleoprotein A1-like 2 OS=Homo sapiens OX=9606 GN=HNRNPA1L2 PE=2 SV=2 8.22 2455.8 - 6.44E+06 - - - -1.2288 - 2.569 0.6 - 474.9 1 1 0 -0.0017 14 0 0 0 3.94E+09 3.27E+08 - - - 5.8398 0.9982 221125_WJC_METTL3_EV_vs_WT_F05.12943.12943.2 0.0117 15/26 R.EQQIVIQSSGGLSK.D "sp|P38646|GRP75_HUMAN,tr|A0A7I2V2S7|A0A7I2V2S7_HUMAN,tr|A0A7I2V2G2|A0A7I2V2G2_HUMAN,tr|H0Y8S0|H0Y8S0_HUMAN,tr|A0A7I2V3F7|A0A7I2V3F7_HUMAN,tr|A0A7I2YQB2|A0A7I2YQB2_HUMAN,tr|D6RCD7|D6RCD7_HUMAN" 7 1472.7835 0.5 64902 12943 2 1472.77698 737.399 "Stress-70 protein, mitochondrial OS=Homo sapiens OX=9606 GN=HSPA9 PE=1 SV=2" 6.1 2455.9 - 2.95E+06 - - - -4.408 - 2.598 0.421 - 754 1 2 0 -0.0065 14 0 0 0 6.60E+07 1.32E+08 - - - 4.5443 0.9998 221125_WJC_METTL3_EV_vs_WT_F05.12944.12944.3 0.00221 Nov-40 R.HETLTSLNLEK[136.11].K "sp|Q96A26|F162A_HUMAN,tr|F8W7Q4|F8W7Q4_HUMAN" 2 1291.6863 1.3 64903 12944 3 1291.684455 431.5694 Protein FAM162A OS=Homo sapiens OX=9606 GN=FAM162A PE=1 SV=2 5.4 2456 - 1.64E+06 - - - -1.4524 - 2.043 0.395 - 240.1 1 2 0 -0.0019 11 0 0 0 2.16E+07 1.67E+07 - - - 4.9729 0.9998 221125_WJC_METTL3_EV_vs_WT_F05.12945.12945.3 0.00375 13/52 R.EQQIVIQSSGGLSK[136.11].D "sp|P38646|GRP75_HUMAN,tr|A0A7I2V2S7|A0A7I2V2S7_HUMAN,tr|A0A7I2V2G2|A0A7I2V2G2_HUMAN,tr|H0Y8S0|H0Y8S0_HUMAN,tr|A0A7I2V3F7|A0A7I2V3F7_HUMAN,tr|A0A7I2YQB2|A0A7I2YQB2_HUMAN,tr|D6RCD7|D6RCD7_HUMAN" 7 1480.7977 0.52 64904 12945 3 1480.796652 494.6065 "Stress-70 protein, mitochondrial OS=Homo sapiens OX=9606 GN=HSPA9 PE=1 SV=2" 6.1 2456.2 - 1.23E+06 - - - -0.6888 - 2.423 0.346 - 216.5 1 2 0 -0.001 14 0 0 0 6.19E+06 1.20E+07 - - - 4.7492 0.999 221125_WJC_METTL3_EV_vs_WT_F05.12946.12946.3 0.0105 Oct-32 R.DWEQFHQPR[166.11].N sp|Q9H773|DCTP1_HUMAN 1 1251.566 0.5 64905 12946 3 1251.56454 418.196 dCTP pyrophosphatase 1 OS=Homo sapiens OX=9606 GN=DCTPP1 PE=1 SV=1 5.32 2456.3 - 1.04E+06 - - - -1.1985 - 1.763 0.279 - 253.6 1 2 0 -0.0015 9 0 0 0 6.80E+06 1.36E+07 - - - 3.359 0.9998 221125_WJC_METTL3_EV_vs_WT_F05.12947.12947.3 0.0472 14/44 K.KVEAQLQELQVK.F sp|P35579|MYH9_HUMAN 1 1411.8035 1.05 64906 12947 3 1411.802761 471.6084 Myosin-9 OS=Homo sapiens OX=9606 GN=MYH9 PE=1 SV=4 6.14 2456.4 - 760581 - - - -0.5086 - 2.647 0.306 - 405.5 1 2 0 -0.0007 12 0 0 0 1.47E+07 1.40E+07 - - - 4.6496 0.9997 221125_WJC_METTL3_EV_vs_WT_F05.12948.12948.2 1.01E-05 26-Nov R.SSTLSSSSMSLSPK.L sp|O15119|TBX3_HUMAN 1 1397.6708 0.93 64907 12948 2 1397.667834 699.8427 T-box transcription factor TBX3 OS=Homo sapiens OX=9606 GN=TBX3 PE=1 SV=4 8.47 2456.6 - 576722 - - - -2.1293 - 2.352 0.499 - 366.9 1 2 0 -0.003 14 0 0 0 1.03E+07 1.11E+07 - - - 4.8719 0.9998 221125_WJC_METTL3_EV_vs_WT_F05.12952.12952.3 8.40E-05 17/60 R.LAEFSSQAAEEEEKVK.S "sp|Q7Z406|MYH14_HUMAN,tr|A0A0C4DFM8|A0A0C4DFM8_HUMAN" 2 1793.8683 0.9 64911 12952 3 1793.863563 598.9634 Myosin-14 OS=Homo sapiens OX=9606 GN=MYH14 PE=1 SV=2 4.33 2457.1 - 592706 - - - -2.654 - 3.157 0.546 - 412.6 1 2 1 -0.0048 16 0 0 0 4.12E+06 4.60E+06 - - - 7.5758 0.9997 221125_WJC_METTL3_EV_vs_WT_F05.12955.12955.3 0.000175 15/48 K.TKAPDDLVAPVVK.K sp|O43172|PRP4_HUMAN 1 1351.7711 3.24 64912 12955 3 1351.768388 451.5976 U4\U6 small nuclear ribonucleoprotein Prp4 OS=Homo sapiens OX=9606 GN=PRPF4 PE=1 SV=2 5.63 2457.5 - 1.78E+06 - - - -2.0188 - 2.682 0.455 - 419.9 1 2 1 -0.0027 13 0 0 0 1.65E+08 5.09E+07 - - - 6.2869 0.999 221125_WJC_METTL3_EV_vs_WT_F05.12957.12957.3 0.0612 Sep-36 R.DFESHITSYK[136.11].Q "sp|Q99613|EIF3C_HUMAN,sp|B5ME19|EIFCL_HUMAN,tr|H3BPE3|H3BPE3_HUMAN" 3 1233.5757 1.01 64914 12957 3 1233.573077 412.1992 Eukaryotic translation initiation factor 3 subunit C OS=Homo sapiens OX=9606 GN=EIF3C PE=1 SV=1 5.32 2457.6 - 1.81E+06 - - - -2.1409 - 1.76 0.329 - 123.4 1 2 0 -0.0026 10 0 0 0 1.78E+07 1.76E+07 - - - 3.8583 0.9998 221125_WJC_METTL3_EV_vs_WT_F05.12958.12958.3 0.00483 Oct-36 R.DFESHITSYK.Q "sp|Q99613|EIF3C_HUMAN,sp|B5ME19|EIFCL_HUMAN,tr|H3BPE3|H3BPE3_HUMAN" 3 1225.5615 1.01 64915 12958 3 1225.55831 409.5278 Eukaryotic translation initiation factor 3 subunit C OS=Homo sapiens OX=9606 GN=EIF3C PE=1 SV=1 5.32 2457.8 - 1.16E+06 - - - -2.6176 - 2.21 0.429 - 162.7 1 2 0 -0.0032 10 0 0 0 1.78E+07 1.76E+07 - - - 5.6379 0.9999 221125_WJC_METTL3_EV_vs_WT_F05.12959.12959.3 0.00401 Oct-32 R.DWEQFHQPR.N sp|Q9H773|DCTP1_HUMAN 1 1241.5578 0.5 64916 12959 3 1241.556631 414.8599 dCTP pyrophosphatase 1 OS=Homo sapiens OX=9606 GN=DCTPP1 PE=1 SV=1 5.32 2457.9 - 920404 - - - -0.9174 - 2.016 0.428 - 276.1 1 2 0 -0.0011 9 0 0 0 6.80E+06 1.36E+07 - - - 5.4245 0.9998 221125_WJC_METTL3_EV_vs_WT_F05.12960.12960.3 6.53E-05 16/56 R.VPIPVK[136.11]ESIEEPSAK[136.11].L "sp|O75643|U520_HUMAN,tr|A0A494C1A5|A0A494C1A5_HUMAN" 2 1637.9211 1.96 64917 12960 3 1637.917296 546.981 U5 small nuclear ribonucleoprotein 200 kDa helicase OS=Homo sapiens OX=9606 GN=SNRNP200 PE=1 SV=2 4.79 2458 - 638937 - - - -2.3151 - 3.001 0.495 - 355.8 1 2 1 -0.0038 15 0 0 0 1.06E+07 5.39E+06 - - - 6.9253 0.9997 221125_WJC_METTL3_EV_vs_WT_F05.12961.12961.3 0.00969 Dec-48 K.TK[136.11]APDDLVAPVVK[136.11].K sp|O43172|PRP4_HUMAN 1 1367.7995 3.23 64918 12961 3 1367.798373 456.9404 U4\U6 small nuclear ribonucleoprotein Prp4 OS=Homo sapiens OX=9606 GN=PRPF4 PE=1 SV=2 5.63 2458.1 - 578694 - - - -0.8364 - 2.646 0.404 - 287.9 1 2 1 -0.0011 13 0 0 0 1.65E+08 5.10E+07 - - - 5.6821 0.9998 221125_WJC_METTL3_EV_vs_WT_F05.12962.12962.2 0.00256 20-Sep R.NSSISGPFGSR.S "sp|Q13610|PWP1_HUMAN,tr|B4DJV5|B4DJV5_HUMAN" 2 1107.5309 2.65 64919 12962 2 1107.529509 554.7727 Periodic tryptophan protein 1 homolog OS=Homo sapiens OX=9606 GN=PWP1 PE=1 SV=1 9.75 2458.3 - 567255 - - - -1.2433 - 2 0.482 - 231.5 1 2 0 -0.0014 11 0 0 0 7.35E+06 2.77E+06 - - - 4.4757 1 221125_WJC_METTL3_EV_vs_WT_F05.12963.12963.2 9.16E-08 20-Nov K.VSSQSFSEIER.Q "sp|Q8N6H7|ARFG2_HUMAN,tr|E9PIY6|E9PIY6_HUMAN,tr|E9PQP3|E9PQP3_HUMAN,tr|G5E9L0|G5E9L0_HUMAN,tr|A0A0D9SF70|A0A0D9SF70_HUMAN" 5 1267.6044 0.55 64920 12963 2 1267.602921 634.8095 ADP-ribosylation factor GTPase-activating protein 2 OS=Homo sapiens OX=9606 GN=ARFGAP2 PE=1 SV=1 4.53 2458.4 - 449530 - - - -1.2023 - 2.737 0.556 - 490.7 1 2 0 -0.0015 11 0 0 0 6.24E+06 1.14E+07 - - - 5.8709 0.985 221125_WJC_METTL3_EV_vs_WT_F05.12965.12965.2 0.00213 28-Sep R.SGANVLIC[160.03]GPNGC[160.03]GK[136.11].S "sp|P28288|ABCD3_HUMAN,tr|A0A3B3ITW3|A0A3B3ITW3_HUMAN" 2 1510.7112 -1 64922 12965 2 1510.719871 756.3629 ATP-binding cassette sub-family D member 3 OS=Homo sapiens OX=9606 GN=ABCD3 PE=1 SV=1 7.79 2458.7 - 370857 - - - 5.7509 - 1.662 0.383 - 161 1 2 0 0.0087 15 0 0 0 0.00E+00 0.00E+00 - - - 3.1161 0.9999 221125_WJC_METTL3_EV_vs_WT_F05.12966.12966.2 2.76E-05 20-Nov K.ISNYGWDQSDK[136.11].F sp|Q9HB71|CYBP_HUMAN 1 1319.5873 0.43 64923 12966 2 1319.586661 660.8009 Calcyclin-binding protein OS=Homo sapiens OX=9606 GN=CACYBP PE=1 SV=2 4.21 2458.8 - 348604 - - - -0.5183 - 2.354 0.546 - 591 1 2 0 -0.0007 11 0 0 0 2.30E+06 5.33E+06 - - - 5.3895 0.9941 221125_WJC_METTL3_EV_vs_WT_F05.12967.12967.2 0.0641 22-Jun K.DLHDANTDLIGR[166.11].H "sp|P53985|MOT1_HUMAN,tr|Q5T8R3|Q5T8R3_HUMAN,tr|Q5T8R5|Q5T8R5_HUMAN" 3 1348.6611 0.89 64924 12967 2 1348.658027 675.3378 Monocarboxylate transporter 1 OS=Homo sapiens OX=9606 GN=SLC16A1 PE=1 SV=3 4.41 2458.9 - 299147 - - - -2.2504 - 1.228 0.284 - 69.6 1 2 0 -0.003 12 0 0 0 2.94E+07 3.32E+07 - - - 1.6781 0.9999 221125_WJC_METTL3_EV_vs_WT_F05.12968.12968.2 5.51E-08 28-Oct K.EVEIVASSDSSISSK.A sp|Q6P2E9|EDC4_HUMAN 1 1536.7519 28.62 64925 12968 2 1536.751275 769.3832 Enhancer of mRNA-decapping protein 4 OS=Homo sapiens OX=9606 GN=EDC4 PE=1 SV=1 4.14 2459.1 - 233438 - - - -0.4047 - 2.233 0.61 - 256.7 1 2 0 -0.0006 15 0 0 0 6.65E+06 2.32E+05 - - - 5.5213 0.9999 221125_WJC_METTL3_EV_vs_WT_F05.12972.12972.3 3.52E-06 15/56 R.VPIPVKESIEEPSAK.L "sp|O75643|U520_HUMAN,tr|A0A494C1A5|A0A494C1A5_HUMAN" 2 1621.8927 1.96 64927 12972 3 1621.890685 541.6382 U5 small nuclear ribonucleoprotein 200 kDa helicase OS=Homo sapiens OX=9606 GN=SNRNP200 PE=1 SV=2 4.79 2459.6 - 1.35E+06 - - - -1.235 - 2.847 0.537 - 291.1 1 2 1 -0.002 15 0 0 0 1.06E+07 5.39E+06 - - - 7.2566 1 221125_WJC_METTL3_EV_vs_WT_F05.12973.12973.2 4.99E-09 26-Dec R.SSGPYGGGGQYFAK.P "sp|Q32P51|RA1L2_HUMAN,sp|P09651|ROA1_HUMAN,tr|A0A7I2YQX9|A0A7I2YQX9_HUMAN,tr|A0A7I2V5N7|A0A7I2V5N7_HUMAN,tr|A0A7I2V661|A0A7I2V661_HUMAN,tr|A0A7I2V520|A0A7I2V520_HUMAN,tr|A0A7I2V2F1|A0A7I2V2F1_HUMAN,tr|A0A7I2V497|A0A7I2V497_HUMAN,tr|A0A7I2V3K5|A0A7I2V3K5_HUMAN,tr|A0A7I2V2M7|A0A7I2V2M7_HUMAN,tr|A0A7I2V4P7|A0A7I2V4P7_HUMAN,tr|A0A7I2V5P1|A0A7I2V5P1_HUMAN,tr|A0A7I2V334|A0A7I2V334_HUMAN,tr|A0A7I2V4E2|A0A7I2V4E2_HUMAN,tr|A0A7I2V4F8|A0A7I2V4F8_HUMAN,tr|A0A7I2V3R8|A0A7I2V3R8_HUMAN,tr|F8W6I7|F8W6I7_HUMAN,tr|A0A7I2V666|A0A7I2V666_HUMAN,tr|A0A7I2V2Q7|A0A7I2V2Q7_HUMAN,tr|A0A7I2V459|A0A7I2V459_HUMAN,tr|A0A7I2YQY2|A0A7I2YQY2_HUMAN,tr|H0YH80|H0YH80_HUMAN,tr|A0A7I2V3W0|A0A7I2V3W0_HUMAN,tr|A0A7I2V3U8|A0A7I2V3U8_HUMAN,tr|A0A7I2V2R4|A0A7I2V2R4_HUMAN,tr|A0A7I2V2X1|A0A7I2V2X1_HUMAN,tr|A0A7I2V453|A0A7I2V453_HUMAN,tr|A0A7I2V360|A0A7I2V360_HUMAN" 28 1374.6204 12.06 64928 12973 2 1374.620348 688.3175 Heterogeneous nuclear ribonucleoprotein A1-like 2 OS=Homo sapiens OX=9606 GN=HNRNPA1L2 PE=2 SV=2 8.22 2459.6 - 4.01E+06 - - - -0.0597 - 2.412 0.625 - 383.9 1 1 0 -0.0001 14 0 0 0 3.94E+09 3.27E+08 - - - 5.8667 0.9995 221125_WJC_METTL3_EV_vs_WT_F05.12974.12974.3 0.000125 14/44 R.SSLLEKGLDGAK.K sp|P81605|DCD_HUMAN 1 1216.6663 999 64929 12974 3 1216.664713 406.5627 Dermcidin OS=Homo sapiens OX=9606 GN=DCD PE=1 SV=2 5.79 2459.7 - 1.05E+06 - - - -1.3184 - 2.33 0.387 - 221.5 1 2 1 -0.0016 12 0 0 0 5.78E+06 0.00E+00 - - - 5.1988 0.9997 221125_WJC_METTL3_EV_vs_WT_F05.12975.12975.2 0.0153 16-Sep K.VELQELNDR.F "sp|P08670|VIME_HUMAN,sp|P17661|DESM_HUMAN,tr|B0YJC4|B0YJC4_HUMAN,tr|A0A1B0GTT5|A0A1B0GTT5_HUMAN" 4 1114.5619 1.18 64930 12975 2 1114.561649 558.2882 Vimentin OS=Homo sapiens OX=9606 GN=VIM PE=1 SV=4 4.14 2459.8 - 1.03E+06 - - - -0.1821 - 1.975 0.346 - 448.9 1 2 0 -0.0002 9 0 0 0 8.95E+06 7.58E+06 - - - 3.5654 0.9981 221125_WJC_METTL3_EV_vs_WT_F05.12976.12976.3 0.0966 Aug-32 R.EWQHEEFYR[166.11].Y "sp|Q12931|TRAP1_HUMAN,tr|I3L0K7|I3L0K7_HUMAN,tr|I3L239|I3L239_HUMAN" 3 1332.5763 1.84 64931 12976 3 1332.575613 445.1994 "Heat shock protein 75 kDa, mitochondrial OS=Homo sapiens OX=9606 GN=TRAP1 PE=1 SV=3" 4.75 2459.9 - 761670 - - - -0.493 - 1.483 0.28 - 95.2 1 2 0 -0.0007 9 0 0 0 2.70E+07 1.47E+07 - - - 2.8492 1 221125_WJC_METTL3_EV_vs_WT_F05.12977.12977.3 6.26E-08 18/60 R.LAEFSSQAAEEEEKVK.S "sp|Q7Z406|MYH14_HUMAN,tr|A0A0C4DFM8|A0A0C4DFM8_HUMAN" 2 1793.8683 0.92 64932 12977 3 1793.867508 598.9634 Myosin-14 OS=Homo sapiens OX=9606 GN=MYH14 PE=1 SV=2 4.33 2460.1 - 606285 - - - -0.4549 - 3.537 0.616 - 382.8 1 2 1 -0.0008 16 0 0 0 4.12E+06 4.46E+06 - - - 8.649 0.9995 221125_WJC_METTL3_EV_vs_WT_F05.12978.12978.2 1.18E-05 26-Dec R.SSTLSSSSMSLSPK[136.11].L sp|O15119|TBX3_HUMAN 1 1405.685 0.93 64933 12978 2 1405.689027 703.8498 T-box transcription factor TBX3 OS=Homo sapiens OX=9606 GN=TBX3 PE=1 SV=4 8.47 2460.2 - 603094 - - - 2.8577 - 2.181 0.522 - 408.1 1 2 0 0.004 14 0 0 0 1.03E+07 1.11E+07 - - - 4.8521 0.9986 221125_WJC_METTL3_EV_vs_WT_F05.12979.12979.3 2.96E-06 15/60 R.LAEFSSQAAEEEEK[136.11]VK[136.11].S "sp|Q7Z406|MYH14_HUMAN,tr|A0A0C4DFM8|A0A0C4DFM8_HUMAN" 2 1809.8967 0.92 64934 12979 3 1809.900066 604.3062 Myosin-14 OS=Homo sapiens OX=9606 GN=MYH14 PE=1 SV=2 4.33 2460.3 - 536776 - - - 1.8465 - 2.088 0.385 - 165.9 1 2 1 0.0033 16 0 0 0 4.12E+06 4.46E+06 - - - 4.7205 0.9986 221125_WJC_METTL3_EV_vs_WT_F05.12980.12980.2 9.16E-06 24-Dec K.TKAPDDLVAPVVK.K sp|O43172|PRP4_HUMAN 1 1351.7711 3.01 64935 12980 2 1351.769265 676.8928 U4\U6 small nuclear ribonucleoprotein Prp4 OS=Homo sapiens OX=9606 GN=PRPF4 PE=1 SV=2 5.63 2460.5 - 536079 - - - -1.3701 - 2.683 0.55 - 429.5 1 2 1 -0.0019 13 0 0 0 1.80E+07 5.99E+06 - - - 5.6357 0.9846 221125_WJC_METTL3_EV_vs_WT_F05.12982.12982.2 2.47E-06 14/22 L.FGGAKPVDTAAR.E "sp|P23588|IF4B_HUMAN,tr|E7EX17|E7EX17_HUMAN,tr|F8VX11|F8VX11_HUMAN" 3 1188.6251 3.29 64937 12982 2 1188.622303 595.3198 Eukaryotic translation initiation factor 4B OS=Homo sapiens OX=9606 GN=EIF4B PE=1 SV=2 8.75 2460.7 - 417658 - - - -2.3708 - 2.223 0.577 - 483.5 1 1 0 -0.0028 12 0 0 0 4.20E+06 1.28E+06 - - - 5.4038 0.9401 221125_WJC_METTL3_EV_vs_WT_F05.12984.12984.3 0.0189 Aug-44 R.EWYAHNPYPSPR.E "sp|Q9NPC8|SIX2_HUMAN,sp|Q15475|SIX1_HUMAN" 2 1515.6895 1.42 64939 12984 3 1515.697286 506.2371 Homeobox protein SIX2 OS=Homo sapiens OX=9606 GN=SIX2 PE=1 SV=1 6.85 2461 - 353135 - - - 5.129 - 1.595 0.236 - 73.3 1 2 0 0.0078 12 0 0 0 7.74E+06 5.46E+06 - - - 2.4631 0.9999 221125_WJC_METTL3_EV_vs_WT_F05.12986.12986.3 0.00112 Dec-56 R.LGLDPTQEDC[160.03]VATHR[166.11].L "sp|P52789|HXK2_HUMAN,tr|E9PB90|E9PB90_HUMAN" 2 1720.8078 13.39 64941 12986 3 1720.81053 574.6099 Hexokinase-2 OS=Homo sapiens OX=9606 GN=HK2 PE=1 SV=2 4.54 2461.3 - 333903 - - - 1.5847 - 2.433 0.396 - 172 1 2 0 0.0027 15 0 0 0 4.23E+07 3.16E+06 - - - 5.2743 0.9991 221125_WJC_METTL3_EV_vs_WT_F05.12989.12989.2 0.0253 18-Nov R.RIDISPSTLR.K "sp|Q9NYF8|BCLF1_HUMAN,tr|E9PKI6|E9PKI6_HUMAN,tr|A0A1W2PQ43|A0A1W2PQ43_HUMAN,tr|E9PK91|E9PK91_HUMAN,tr|E9PK09|E9PK09_HUMAN,tr|E9PQN2|E9PQN2_HUMAN" 6 1156.6564 2.2 64944 12989 2 1156.657308 579.3355 Bcl-2-associated transcription factor 1 OS=Homo sapiens OX=9606 GN=BCLAF1 PE=1 SV=2 9.6 2461.7 - 210080 - - - 0.7669 - 1.76 0.268 - 229.3 1 2 0 0.0009 10 0 0 0 3.75E+06 1.71E+06 - - - 2.5981 0.9869 221125_WJC_METTL3_EV_vs_WT_F05.12990.12990.2 0.00442 22-Dec R.KANVNLAYLGAK.P "sp|Q9H0Z9|RBM38_HUMAN,sp|Q9BX46|RBM24_HUMAN,tr|A6NG75|A6NG75_HUMAN,tr|H0Y8S7|H0Y8S7_HUMAN,tr|H0YA61|H0YA61_HUMAN,tr|F6VZ39|F6VZ39_HUMAN" 6 1260.719 7.41 64945 12990 2 1260.719307 631.3668 RNA-binding protein 38 OS=Homo sapiens OX=9606 GN=RBM38 PE=1 SV=2 9.7 2461.8 - 156103 - - - 0.2269 - 2.419 0.354 - 452.8 1 1 0 0.0003 12 0 0 0 1.13E+06 1.52E+05 - - - 3.9798 1 221125_WJC_METTL3_EV_vs_WT_F05.12992.12992.2 6.41E-06 14/26 R.QYFPNDEDQVGAAK.A sp|P13674|P4HA1_HUMAN 1 1580.7107 2.76 64946 12992 2 1580.709355 791.3626 Prolyl 4-hydroxylase subunit alpha-1 OS=Homo sapiens OX=9606 GN=P4HA1 PE=1 SV=2 4.03 2462.1 - 1.12E+06 - - - -0.8515 - 2.644 0.644 - 641.1 1 2 0 -0.0013 14 0 0 0 2.02E+08 7.33E+07 - - - 6.2371 0.9999 221125_WJC_METTL3_EV_vs_WT_F05.12994.12994.3 3.02E-06 16/44 K.NLDDGIDDERLR.K "sp|Q9H361|PABP3_HUMAN,sp|P11940|PABP1_HUMAN,tr|A0A7I2YQE4|A0A7I2YQE4_HUMAN,tr|A0A7I2V649|A0A7I2V649_HUMAN,tr|H0YAR2|H0YAR2_HUMAN,tr|E7ERJ7|E7ERJ7_HUMAN,tr|A0A7I2YQ88|A0A7I2YQ88_HUMAN,tr|A0A087WTT1|A0A087WTT1_HUMAN,tr|H0YAP2|H0YAP2_HUMAN,tr|A0A7I2V4N4|A0A7I2V4N4_HUMAN,tr|E7EQV3|E7EQV3_HUMAN" 11 1429.6797 1.52 64948 12994 3 1429.680195 477.5672 Polyadenylate-binding protein 3 OS=Homo sapiens OX=9606 GN=PABPC3 PE=1 SV=2 4.04 2462.3 - 5.46E+06 - - - 0.3218 - 2.218 0.564 - 525.2 1 2 1 0.0005 12 0 0 0 5.09E+07 3.36E+07 - - - 7.036 0.9999 221125_WJC_METTL3_EV_vs_WT_F05.12995.12995.3 7.16E-06 14/44 K.NLDDGIDDER[166.11]LR[166.11].K "sp|Q9H361|PABP3_HUMAN,sp|P11940|PABP1_HUMAN,tr|A0A7I2YQE4|A0A7I2YQE4_HUMAN,tr|A0A7I2V649|A0A7I2V649_HUMAN,tr|H0YAR2|H0YAR2_HUMAN,tr|E7ERJ7|E7ERJ7_HUMAN,tr|A0A7I2YQ88|A0A7I2YQ88_HUMAN,tr|A0A087WTT1|A0A087WTT1_HUMAN,tr|H0YAP2|H0YAP2_HUMAN,tr|A0A7I2V4N4|A0A7I2V4N4_HUMAN,tr|E7EQV3|E7EQV3_HUMAN" 11 1449.6963 1.52 64949 12995 3 1449.695791 484.2394 Polyadenylate-binding protein 3 OS=Homo sapiens OX=9606 GN=PABPC3 PE=1 SV=2 4.04 2462.4 - 4.62E+06 - - - -0.3339 - 2.019 0.565 - 377.6 1 2 1 -0.0005 12 0 0 0 5.09E+07 3.36E+07 - - - 6.7866 0.9999 221125_WJC_METTL3_EV_vs_WT_F05.12996.12996.3 0.00189 13/40 R.ISHGEVLEWQK.T "sp|Q9BXP5|SRRT_HUMAN,tr|H7C3A1|H7C3A1_HUMAN" 2 1324.6776 1.25 64950 12996 3 1324.677518 442.5665 Serrate RNA effector molecule homolog OS=Homo sapiens OX=9606 GN=SRRT PE=1 SV=1 5.4 2462.4 - 1.94E+06 - - - -0.0249 - 2.37 0.372 - 438 1 2 0 0 11 0 0 0 9.94E+06 7.95E+06 - - - 5.1387 0.9999 221125_WJC_METTL3_EV_vs_WT_F05.12997.12997.3 9.22E-05 Dec-40 R.ISHGEVLEWQK[136.11].T "sp|Q9BXP5|SRRT_HUMAN,tr|H7C3A1|H7C3A1_HUMAN" 2 1332.6918 1.97 64951 12997 3 1332.691741 445.2379 Serrate RNA effector molecule homolog OS=Homo sapiens OX=9606 GN=SRRT PE=1 SV=1 5.4 2462.5 - 1.77E+06 - - - -0.0075 - 2.251 0.432 - 263.7 1 2 0 0 11 0 0 0 1.96E+07 9.94E+06 - - - 5.6613 0.9999 221125_WJC_METTL3_EV_vs_WT_F05.12998.12998.3 7.51E-05 14/52 K.VDEAVAVLQAHQAK.E "sp|Q9H361|PABP3_HUMAN,sp|P11940|PABP1_HUMAN,tr|H0YAS6|H0YAS6_HUMAN,tr|H0YB75|H0YB75_HUMAN,tr|H0YAS7|H0YAS7_HUMAN,tr|A0A7I2YQE4|A0A7I2YQE4_HUMAN,tr|A0A7I2V649|A0A7I2V649_HUMAN,tr|H0YC10|H0YC10_HUMAN,tr|H0YAR2|H0YAR2_HUMAN,tr|E7ERJ7|E7ERJ7_HUMAN,tr|A0A7I2YQ88|A0A7I2YQ88_HUMAN,tr|A0A087WTT1|A0A087WTT1_HUMAN,tr|A0A7I2YQ90|A0A7I2YQ90_HUMAN,tr|A0A7I2V4N4|A0A7I2V4N4_HUMAN,tr|E7EQV3|E7EQV3_HUMAN" 15 1477.7889 -1 64952 12998 3 1477.787459 493.6036 Polyadenylate-binding protein 3 OS=Homo sapiens OX=9606 GN=PABPC3 PE=1 SV=2 5.32 2462.5 - 1.32E+06 - - - -0.9697 - 2.789 0.405 - 302.4 1 2 0 -0.0014 14 0 0 0 0.00E+00 0.00E+00 - - - 5.7807 0.9999 221125_WJC_METTL3_EV_vs_WT_F05.12999.12999.3 1.07E-05 14/52 K.VDEAVAVLQAHQAK[136.11].E "sp|Q9H361|PABP3_HUMAN,sp|P11940|PABP1_HUMAN,tr|H0YAS6|H0YAS6_HUMAN,tr|H0YB75|H0YB75_HUMAN,tr|H0YAS7|H0YAS7_HUMAN,tr|A0A7I2YQE4|A0A7I2YQE4_HUMAN,tr|A0A7I2V649|A0A7I2V649_HUMAN,tr|H0YC10|H0YC10_HUMAN,tr|H0YAR2|H0YAR2_HUMAN,tr|E7ERJ7|E7ERJ7_HUMAN,tr|A0A7I2YQ88|A0A7I2YQ88_HUMAN,tr|A0A087WTT1|A0A087WTT1_HUMAN,tr|A0A7I2YQ90|A0A7I2YQ90_HUMAN,tr|A0A7I2V4N4|A0A7I2V4N4_HUMAN,tr|E7EQV3|E7EQV3_HUMAN" 15 1485.8031 1.99 64953 12999 3 1485.806062 496.275 Polyadenylate-binding protein 3 OS=Homo sapiens OX=9606 GN=PABPC3 PE=1 SV=2 5.32 2462.6 - 791196 - - - 1.9989 - 2.596 0.455 - 310.5 1 2 0 0.003 14 0 0 0 1.33E+07 6.70E+06 - - - 6.1472 0.9966 221125_WJC_METTL3_EV_vs_WT_F05.13002.13002.3 0.0501 Oct-48 K.VSHVLAALQAGNR[166.11].G sp|Q9Y490|TLN1_HUMAN 1 1344.7502 0.35 64956 13002 3 1344.74979 449.2573 Talin-1 OS=Homo sapiens OX=9606 GN=TLN1 PE=1 SV=3 9.73 2463 - 598025 - - - -0.2692 - 1.75 0.217 - 121.6 1 2 0 -0.0004 13 0 0 0 1.37E+06 3.90E+06 - - - 2.4765 0.9997 221125_WJC_METTL3_EV_vs_WT_F05.13003.13003.2 1.18E-05 24-Oct K.SSVNC[160.03]PFSSQDMK.Y sp|Q08211|DHX9_HUMAN 1 1485.6228 0.94 64957 13003 2 1485.625812 743.8187 ATP-dependent RNA helicase A OS=Homo sapiens OX=9606 GN=DHX9 PE=1 SV=4 5.55 2463.1 - 593447 - - - 2.018 - 1.993 0.551 - 130.8 1 2 0 0.003 13 0 0 0 2.67E+07 2.85E+07 - - - 4.8797 1 221125_WJC_METTL3_EV_vs_WT_F05.13005.13005.2 9.77E-08 14/24 K.TK[136.11]APDDLVAPVVK[136.11].K sp|O43172|PRP4_HUMAN 1 1367.7995 3.01 64959 13005 2 1367.800863 684.907 U4\U6 small nuclear ribonucleoprotein Prp4 OS=Homo sapiens OX=9606 GN=PRPF4 PE=1 SV=2 5.63 2463.4 - 503234 - - - 0.9841 - 2.901 0.626 - 530.7 1 2 1 0.0013 13 0 0 0 1.80E+07 5.99E+06 - - - 6.3977 0.9999 221125_WJC_METTL3_EV_vs_WT_F05.13006.13006.3 9.48E-07 16/56 K.LVPLDYGEDDK[136.11]NATK[136.11].G sp|P49756|RBM25_HUMAN 1 1692.8541 0.97 64960 13006 3 1692.855875 565.292 RNA-binding protein 25 OS=Homo sapiens OX=9606 GN=RBM25 PE=1 SV=3 4.23 2463.5 - 488027 - - - 1.0302 - 3.006 0.543 - 299.9 1 2 1 0.0017 15 0 0 0 6.66E+06 6.85E+06 - - - 7.4653 0.9997 221125_WJC_METTL3_EV_vs_WT_F05.13008.13008.3 0.0737 Nov-36 R.R[166.11]IDISPSTLR[166.11].K "sp|Q9NYF8|BCLF1_HUMAN,tr|E9PKI6|E9PKI6_HUMAN,tr|A0A1W2PQ43|A0A1W2PQ43_HUMAN,tr|E9PK91|E9PK91_HUMAN,tr|E9PK09|E9PK09_HUMAN,tr|E9PQN2|E9PQN2_HUMAN" 6 1176.673 2.68 64962 13008 3 1176.672983 393.2316 Bcl-2-associated transcription factor 1 OS=Homo sapiens OX=9606 GN=BCLAF1 PE=1 SV=2 9.6 2463.8 - 401570 - - - 0.0187 - 2.242 0.307 - 213.8 1 2 0 0 10 0 0 0 8.87E+06 3.30E+06 - - - 4.3206 0.995 221125_WJC_METTL3_EV_vs_WT_F05.13013.13013.3 0.0154 15/44 R.KANVNLAYLGAK.P "sp|Q9H0Z9|RBM38_HUMAN,sp|Q9BX46|RBM24_HUMAN,tr|A6NG75|A6NG75_HUMAN,tr|H0Y8S7|H0Y8S7_HUMAN,tr|H0YA61|H0YA61_HUMAN,tr|F6VZ39|F6VZ39_HUMAN" 6 1260.719 3.23 64966 13013 3 1260.717694 421.247 RNA-binding protein 38 OS=Homo sapiens OX=9606 GN=RBM38 PE=1 SV=2 9.7 2464.4 - 748790 - - - -1.0526 - 2.875 0.405 - 448.5 1 1 0 -0.0013 12 0 0 0 3.35E+06 1.04E+06 - - - 5.9822 0.9997 221125_WJC_METTL3_EV_vs_WT_F05.13017.13017.2 2.93E-05 18-Oct R.DFESHITSYK.Q "sp|Q99613|EIF3C_HUMAN,sp|B5ME19|EIFCL_HUMAN,tr|H3BPE3|H3BPE3_HUMAN" 3 1225.5615 1.04 64970 13017 2 1225.561673 613.788 Eukaryotic translation initiation factor 3 subunit C OS=Homo sapiens OX=9606 GN=EIF3C PE=1 SV=1 5.32 2464.8 - 687502 - - - 0.1265 - 1.784 0.4 - 301.4 1 2 0 0.0002 10 0 0 0 4.82E+06 4.64E+06 - - - 3.6111 0.9999 221125_WJC_METTL3_EV_vs_WT_F05.13019.13019.3 2.43E-05 13/48 R.IQFKPDDGISPER.A sp|Q96I24|FUBP3_HUMAN 1 1500.7573 1.95 64972 13019 3 1500.759105 501.2597 Far upstream element-binding protein 3 OS=Homo sapiens OX=9606 GN=FUBP3 PE=1 SV=2 4.56 2465 - 560359 - - - 1.2307 - 2.565 0.354 - 192.8 1 2 0 0.0018 13 0 0 0 1.31E+09 6.68E+08 - - - 5.0402 1 221125_WJC_METTL3_EV_vs_WT_F05.13023.13023.2 1.48E-07 17/18 K.RNVIEAVYSR.L "sp|O75688|PPM1B_HUMAN,tr|B8ZZF0|B8ZZF0_HUMAN,tr|A0A3B3IS24|A0A3B3IS24_HUMAN,tr|C9JIR6|C9JIR6_HUMAN" 4 1205.6517 3.5 64976 13023 2 1205.653487 603.8331 Protein phosphatase 1B OS=Homo sapiens OX=9606 GN=PPM1B PE=1 SV=1 8.75 2465.5 - 359225 - - - 1.5071 - 3.017 0.552 - 669 1 2 0 0.0018 10 0 0 0 2.04E+07 5.83E+06 - - - 6.1998 1 221125_WJC_METTL3_EV_vs_WT_F05.13024.13024.2 1.15E-07 24-Nov R.ANENSNIQVLSER.S sp|Q6UN15|FIP1_HUMAN 1 1472.7219 1.12 64977 13024 2 1472.718811 737.3682 Pre-mRNA 3'-end-processing factor FIP1 OS=Homo sapiens OX=9606 GN=FIP1L1 PE=1 SV=1 4.53 2465.7 - 330764 - - - -2.1212 - 2.731 0.572 - 577.5 1 2 0 -0.0031 13 0 0 0 1.92E+06 1.72E+06 - - - 5.8433 0.9991 221125_WJC_METTL3_EV_vs_WT_F05.13026.13026.2 6.60E-05 18-Aug R.YSLDPENPTK[136.11].S "sp|P18621|RL17_HUMAN,tr|A0A087WWH0|A0A087WWH0_HUMAN,tr|J3QS96|J3QS96_HUMAN,tr|J3QQT2|J3QQT2_HUMAN,tr|J3KSJ0|J3KSJ0_HUMAN,tr|A0A087WY81|A0A087WY81_HUMAN,tr|J3KRB3|J3KRB3_HUMAN,tr|J3KRX5|J3KRX5_HUMAN,tr|A0A087WXM6|A0A087WXM6_HUMAN,tr|A0A0A6YYL6|A0A0A6YYL6_HUMAN" 10 1170.5648 1.43 64979 13026 2 1170.563854 586.2897 60S ribosomal protein L17 OS=Homo sapiens OX=9606 GN=RPL17 PE=1 SV=3 4.37 2465.9 - 261212 - - - -0.8244 - 1.646 0.292 - 162 1 2 0 -0.001 10 0 0 0 5.47E+06 3.83E+06 - - - 2.5885 1 221125_WJC_METTL3_EV_vs_WT_F05.13027.13027.3 0.000118 15/36 R.SLHDALC[160.03]VVK.R "sp|P17987|TCPA_HUMAN,tr|F5GZ03|F5GZ03_HUMAN,tr|F5H282|F5H282_HUMAN,tr|E7EQR6|E7EQR6_HUMAN,tr|E7ERF2|E7ERF2_HUMAN" 5 1140.5961 0.33 64980 13027 3 1140.59563 381.206 T-complex protein 1 subunit alpha OS=Homo sapiens OX=9606 GN=TCP1 PE=1 SV=1 6.46 2466 - 222772 - - - -0.4375 - 2.407 0.433 - 322.9 1 2 0 -0.0005 10 0 0 0 1.90E+06 5.77E+06 - - - 5.9326 0.9998 221125_WJC_METTL3_EV_vs_WT_F05.13028.13028.2 1.14E-05 26-Jul R.MQNNEELPTYEEAK[136.11].V sp|Q4VCS5|AMOT_HUMAN 1 1702.76 -1 64981 13028 2 1702.7582 852.3873 Angiomotin OS=Homo sapiens OX=9606 GN=AMOT PE=1 SV=1 4.09 2466.1 - 143650 - - - -1.0371 - 1.56 0.617 - 128.4 1 2 0 -0.0018 14 0 0 0 0.00E+00 0.00E+00 - - - 4.7135 1 221125_WJC_METTL3_EV_vs_WT_F05.13030.13030.3 0.000272 15/36 R.SLHDALC[160.03]VVK[136.11].R "sp|P17987|TCPA_HUMAN,tr|F5GZ03|F5GZ03_HUMAN,tr|F5H282|F5H282_HUMAN,tr|E7EQR6|E7EQR6_HUMAN,tr|E7ERF2|E7ERF2_HUMAN" 5 1148.6103 0.35 64982 13030 3 1148.610209 383.8774 T-complex protein 1 subunit alpha OS=Homo sapiens OX=9606 GN=TCP1 PE=1 SV=1 6.46 2466.4 - 1.32E+06 - - - -0.1045 - 2.47 0.484 - 361.6 1 2 0 -0.0001 10 0 0 0 1.83E+06 5.24E+06 - - - 6.5768 0.9985 221125_WJC_METTL3_EV_vs_WT_F05.13031.13031.2 0.0507 24-Jul K.DASGQPIFNASAK[136.11].H sp|O15226|NKRF_HUMAN 1 1312.6503 0.53 64983 13031 2 1312.650694 657.3324 NF-kappa-B-repressing factor OS=Homo sapiens OX=9606 GN=NKRF PE=1 SV=2 5.84 2466.6 - 307448 - - - 0.3154 - 1.446 0.278 - 135.3 1 2 0 0.0004 13 0 0 0 4.74E+07 8.96E+07 - - - 2.0407 0.9999 221125_WJC_METTL3_EV_vs_WT_F05.13032.13032.3 0.000448 14/48 R.IQFK[136.11]PDDGISPER[166.11].A sp|Q96I24|FUBP3_HUMAN 1 1518.7797 1.95 64984 13032 3 1518.779194 507.2672 Far upstream element-binding protein 3 OS=Homo sapiens OX=9606 GN=FUBP3 PE=1 SV=2 4.56 2466.6 - 1.68E+06 - - - -0.3516 - 2.574 0.412 - 211.1 1 2 0 -0.0005 13 0 0 0 1.31E+09 6.68E+08 - - - 5.6967 1 221125_WJC_METTL3_EV_vs_WT_F05.13033.13033.3 1.57E-05 17/36 K.RNVIEAVYSR.L "sp|O75688|PPM1B_HUMAN,tr|B8ZZF0|B8ZZF0_HUMAN,tr|A0A3B3IS24|A0A3B3IS24_HUMAN,tr|C9JIR6|C9JIR6_HUMAN" 4 1205.6517 3.09 64985 13033 3 1205.651353 402.8912 Protein phosphatase 1B OS=Homo sapiens OX=9606 GN=PPM1B PE=1 SV=1 8.75 2466.7 - 1.66E+06 - - - -0.2629 - 3.118 0.456 - 719.3 1 2 0 -0.0003 10 0 0 0 2.63E+07 8.52E+06 - - - 6.945 0.9992 221125_WJC_METTL3_EV_vs_WT_F05.13034.13034.3 0.000187 Sep-44 K.AFTQLSNLQSHR[166.11].R "sp|Q8TF68|ZN384_HUMAN,tr|A0A804HJE2|A0A804HJE2_HUMAN" 2 1410.7243 0.85 64986 13034 3 1410.720191 471.2487 Zinc finger protein 384 OS=Homo sapiens OX=9606 GN=ZNF384 PE=1 SV=2 9.8 2466.8 - 1.15E+06 - - - -2.9347 - 2.059 0.356 - 94.4 1 2 0 -0.0041 12 0 0 0 3.75E+06 4.39E+06 - - - 4.5098 0.9984 221125_WJC_METTL3_EV_vs_WT_F05.13035.13035.3 3.25E-07 15/60 H.LSNLPHSGYSDSAVLK.L "sp|P43243|MATR3_HUMAN,tr|B3KM87|B3KM87_HUMAN,tr|A8MXP9|A8MXP9_HUMAN,tr|D6RBK5|D6RBK5_HUMAN,tr|A0A0R4J2E8|A0A0R4J2E8_HUMAN,tr|H0Y8T4|H0Y8T4_HUMAN,tr|D6REM6|D6REM6_HUMAN" 7 1686.8577 2.03 64987 13035 3 1686.857545 563.2932 Matrin-3 OS=Homo sapiens OX=9606 GN=MATR3 PE=1 SV=2 6.74 2466.9 - 1.10E+06 - - - -0.0919 - 3.093 0.541 - 351.6 1 1 0 -0.0002 16 0 0 0 8.40E+06 4.13E+06 - - - 7.4688 0.9998 221125_WJC_METTL3_EV_vs_WT_F05.13036.13036.2 0.00022 18-Dec K.NHEEEMLALR.G "sp|P08779|K1C16_HUMAN,tr|K7ENW6|K7ENW6_HUMAN" 2 1240.587 199.16 64988 13036 2 1240.587189 621.3008 "Keratin, type I cytoskeletal 16 OS=Homo sapiens OX=9606 GN=KRT16 PE=1 SV=4" 4.75 2467.1 - 1.04E+06 - - - 0.1354 - 2.179 0.445 - 644.9 1 2 0 0.0002 10 0 0 0 1.42E+07 7.13E+04 - - - 4.5018 1 221125_WJC_METTL3_EV_vs_WT_F05.13037.13037.3 4.39E-07 15/52 R.LYQTDPSGTYHAWK.A "sp|Q8TAA3|PSMA8_HUMAN,sp|O14818|PSA7_HUMAN,tr|A0A087WYS6|A0A087WYS6_HUMAN,tr|H0Y586|H0Y586_HUMAN" 4 1665.7787 0.2 64989 13037 3 1665.778095 556.2669 Proteasome subunit alpha-type 8 OS=Homo sapiens OX=9606 GN=PSMA8 PE=2 SV=3 6.74 2467.2 - 981999 - - - -0.3758 - 3.075 0.579 - 198.4 1 2 0 -0.0006 14 0 0 0 1.01E+07 5.03E+07 - - - 7.9803 0.9999 221125_WJC_METTL3_EV_vs_WT_F05.13038.13038.3 1.77E-05 Nov-36 K.NHEEEMLALR.G "sp|P08779|K1C16_HUMAN,tr|K7ENW6|K7ENW6_HUMAN" 2 1240.587 22.37 64990 13038 3 1240.586154 414.5363 "Keratin, type I cytoskeletal 16 OS=Homo sapiens OX=9606 GN=KRT16 PE=1 SV=4" 4.75 2467.3 - 833035 - - - -0.6989 - 2.147 0.404 - 244.7 1 2 0 -0.0009 10 0 0 0 1.04E+07 4.64E+05 - - - 5.2754 0.9997 221125_WJC_METTL3_EV_vs_WT_F05.13041.13041.2 4.24E-06 15/18 K.R[166.11]NVIEAVYSR[166.11].L "sp|O75688|PPM1B_HUMAN,tr|B8ZZF0|B8ZZF0_HUMAN,tr|A0A3B3IS24|A0A3B3IS24_HUMAN,tr|C9JIR6|C9JIR6_HUMAN" 4 1225.6682 3.55 64993 13041 2 1225.66723 613.8414 Protein phosphatase 1B OS=Homo sapiens OX=9606 GN=PPM1B PE=1 SV=1 8.75 2467.6 - 540021 - - - -0.7996 - 2.335 0.312 - 403 1 2 0 -0.001 10 0 0 0 2.04E+07 5.75E+06 - - - 3.7122 1 221125_WJC_METTL3_EV_vs_WT_F05.13043.13043.3 9.26E-09 14/48 R.FHPEPYGLEDDQR.S "sp|O60716|CTND1_HUMAN,tr|A0A669KB62|A0A669KB62_HUMAN,tr|A0A669KB05|A0A669KB05_HUMAN,tr|C9JZR2|C9JZR2_HUMAN,tr|H0YC95|H0YC95_HUMAN" 5 1601.711 1.33 64995 13043 3 1601.712182 534.911 Catenin delta-1 OS=Homo sapiens OX=9606 GN=CTNND1 PE=1 SV=1 4.31 2467.9 - 470862 - - - 0.7155 - 2.414 0.625 - 320.8 1 2 0 0.0011 13 0 0 0 3.65E+06 2.75E+06 - - - 7.8972 1 221125_WJC_METTL3_EV_vs_WT_F05.13044.13044.3 1.28E-11 20/68 C.LSGAPQASAADVVVVHGR[166.11].R "sp|P09110|THIK_HUMAN,tr|B4DVF4|B4DVF4_HUMAN,tr|F2Z3P7|F2Z3P7_HUMAN,tr|C9JDE9|C9JDE9_HUMAN,tr|F2Z2Q6|F2Z2Q6_HUMAN" 5 1742.9303 1.1 64996 13044 3 1742.928647 581.984 "3-ketoacyl-CoA thiolase, peroxisomal OS=Homo sapiens OX=9606 GN=ACAA1 PE=1 SV=2" 6.74 2468 - 345861 - - - -0.949 - 3.324 0.631 - 526.6 1 1 0 -0.0017 18 0 0 0 2.19E+06 2.00E+06 - - - 8.5656 0.9999 221125_WJC_METTL3_EV_vs_WT_F05.13045.13045.3 8.42E-05 Dec-68 K.LSLEGDHSTPPSAYGSVK[136.11].A "sp|P07355|ANXA2_HUMAN,sp|A6NMY6|AXA2L_HUMAN,tr|H0YMU9|H0YMU9_HUMAN,tr|H0YMD9|H0YMD9_HUMAN,tr|H0YKX9|H0YKX9_HUMAN,tr|H0YMM1|H0YMM1_HUMAN,tr|H0YLV6|H0YLV6_HUMAN,tr|H0YMD0|H0YMD0_HUMAN,tr|H0YKV8|H0YKV8_HUMAN,tr|H0YMW4|H0YMW4_HUMAN,tr|H0YKN4|H0YKN4_HUMAN,tr|H0YN42|H0YN42_HUMAN,tr|A0A7I2V4P4|A0A7I2V4P4_HUMAN,tr|H0YMT9|H0YMT9_HUMAN,tr|H0YKZ7|H0YKZ7_HUMAN,tr|H0YKL9|H0YKL9_HUMAN,tr|H0YNB8|H0YNB8_HUMAN,tr|H0YKS4|H0YKS4_HUMAN" 18 1851.9094 2.04 64997 13045 3 1851.908972 618.3104 Annexin A2 OS=Homo sapiens OX=9606 GN=ANXA2 PE=1 SV=2 5.32 2468.2 - 324623 - - - -0.2354 - 1.907 0.477 - 89.1 1 2 0 -0.0004 18 0 0 0 2.49E+06 1.22E+06 - - - 5.4654 0.9889 221125_WJC_METTL3_EV_vs_WT_F05.13046.13046.3 0.147 Sep-60 R.AEVEALHSSGMTAVVK[136.11].F sp|Q9H7E2|TDRD3_HUMAN 1 1635.8382 0.28 64998 13046 3 1635.834167 546.2867 Tudor domain-containing protein 3 OS=Homo sapiens OX=9606 GN=TDRD3 PE=1 SV=1 5.4 2468.3 - 323743 - - - -2.4391 - 1.863 0.194 - 70.4 1 2 0 -0.004 16 0 0 0 9.30E+05 3.36E+06 - - - 2.2983 1 221125_WJC_METTL3_EV_vs_WT_F05.13047.13047.2 1.54E-07 28-Nov A.MSTLPVEDEESSESR.M "sp|P78347|GTF2I_HUMAN,tr|C9J6M0|C9J6M0_HUMAN,tr|A0A494C1K3|A0A494C1K3_HUMAN" 3 1694.7305 1.42 64999 13047 2 1694.738344 848.3725 General transcription factor II-I OS=Homo sapiens OX=9606 GN=GTF2I PE=1 SV=2 3.91 2468.4 - 303769 - - - 4.6226 - 2.017 0.677 - 241.3 1 1 0 0.0078 15 0 0 0 7.46E+06 5.26E+06 - - - 5.7638 0.9995 221125_WJC_METTL3_EV_vs_WT_F05.13048.13048.2 0.00611 18-Sep R.SLHDALC[160.03]VVK[136.11].R "sp|P17987|TCPA_HUMAN,tr|F5GZ03|F5GZ03_HUMAN,tr|F5H282|F5H282_HUMAN,tr|E7EQR6|E7EQR6_HUMAN,tr|E7ERF2|E7ERF2_HUMAN" 5 1148.6103 0.36 65000 13048 2 1148.609537 575.3124 T-complex protein 1 subunit alpha OS=Homo sapiens OX=9606 GN=TCP1 PE=1 SV=1 6.46 2468.6 - 231058 - - - -0.6895 - 1.766 0.322 - 214 1 2 0 -0.0008 10 0 0 0 5.00E+05 1.38E+06 - - - 3.0065 0.9999 221125_WJC_METTL3_EV_vs_WT_F05.13049.13049.2 2.93E-06 22-Oct R.EADLPDNITNEK.T "sp|Q13127|REST_HUMAN,tr|A0A6Q8PH19|A0A6Q8PH19_HUMAN,tr|A0A1W2PQA1|A0A1W2PQA1_HUMAN" 3 1357.6361 10.69 65001 13049 2 1357.636064 679.8253 RE1-silencing transcription factor OS=Homo sapiens OX=9606 GN=REST PE=1 SV=3 3.92 2468.7 - 220548 - - - -0.0552 - 2.108 0.573 - 295.5 1 2 0 -0.0001 12 0 0 0 1.39E+06 1.30E+05 - - - 5.2353 0.9846 221125_WJC_METTL3_EV_vs_WT_F05.13051.13051.2 0.071 24-Jul K.DASGQPIFNASAK.H sp|O15226|NKRF_HUMAN 1 1304.6361 0.53 65002 13051 2 1304.632721 653.3253 NF-kappa-B-repressing factor OS=Homo sapiens OX=9606 GN=NKRF PE=1 SV=2 5.84 2468.9 - 151335 - - - -2.5747 - 1.277 0.199 - 152.6 1 2 0 -0.0034 13 0 0 0 4.73E+07 8.86E+07 - - - 1.1373 1 221125_WJC_METTL3_EV_vs_WT_F05.13053.13053.3 1.64E-08 15/36 K.R[166.11]NVIEAVYSR[166.11].L "sp|O75688|PPM1B_HUMAN,tr|B8ZZF0|B8ZZF0_HUMAN,tr|A0A3B3IS24|A0A3B3IS24_HUMAN,tr|C9JIR6|C9JIR6_HUMAN" 4 1225.6682 3.09 65004 13053 3 1225.668172 409.5633 Protein phosphatase 1B OS=Homo sapiens OX=9606 GN=PPM1B PE=1 SV=1 8.75 2469.1 - 1.66E+06 - - - -0.031 - 3.081 0.461 - 561.2 1 2 0 0 10 0 0 0 2.63E+07 8.52E+06 - - - 6.9659 1 221125_WJC_METTL3_EV_vs_WT_F05.13054.13054.2 2.11E-11 18/30 R.SIGSAVDQGNESIVAK.T "sp|Q9H0H5|RGAP1_HUMAN,tr|F8VRD2|F8VRD2_HUMAN,tr|F8W1E5|F8W1E5_HUMAN" 3 1573.7948 1.39 65005 13054 2 1573.795655 787.9047 Rac GTPase-activating protein 1 OS=Homo sapiens OX=9606 GN=RACGAP1 PE=1 SV=1 4.37 2469.2 - 866601 - - - 0.5655 - 3.434 0.683 - 779.7 1 2 0 0.0009 16 0 0 0 4.93E+06 3.55E+06 - - - 7.1185 0.9999 221125_WJC_METTL3_EV_vs_WT_F05.13055.13055.3 0.000285 Oct-44 K.RTAAENEFVTLK.K "sp|P48668|K2C6C_HUMAN,sp|P12035|K2C3_HUMAN,sp|P04259|K2C6B_HUMAN,sp|P02538|K2C6A_HUMAN" 4 1377.7252 0.67 65006 13055 3 1377.725746 460.249 "Keratin, type II cytoskeletal 6C OS=Homo sapiens OX=9606 GN=KRT6C PE=1 SV=3" 6.14 2469.3 - 694723 - - - 0.3753 - 2.195 0.411 - 231.4 1 2 0 0.0005 12 0 0 0 3.88E+06 5.80E+06 - - - 5.3013 0.9957 221125_WJC_METTL3_EV_vs_WT_F05.13056.13056.3 0.0414 Jul-44 R.EWYAHNPYPSPR[166.11].E "sp|Q9NPC8|SIX2_HUMAN,sp|Q15475|SIX1_HUMAN" 2 1525.6978 1.55 65007 13056 3 1525.700272 509.5732 Homeobox protein SIX2 OS=Homo sapiens OX=9606 GN=SIX2 PE=1 SV=1 6.85 2469.4 - 748436 - - - 1.632 - 1.528 0.26 - 46.2 1 2 0 0.0025 12 0 0 0 5.44E+06 3.50E+06 - - - 2.6132 1 221125_WJC_METTL3_EV_vs_WT_F05.13057.13057.3 3.64E-05 Dec-48 R.FHPEPYGLEDDQR[166.11].S "sp|O60716|CTND1_HUMAN,tr|A0A669KB62|A0A669KB62_HUMAN,tr|A0A669KB05|A0A669KB05_HUMAN,tr|C9JZR2|C9JZR2_HUMAN,tr|H0YC95|H0YC95_HUMAN" 5 1611.7193 1.3 65008 13057 3 1611.721821 538.247 Catenin delta-1 OS=Homo sapiens OX=9606 GN=CTNND1 PE=1 SV=1 4.31 2469.5 - 620901 - - - 1.5604 - 2.432 0.544 - 213.4 1 2 0 0.0025 13 0 0 0 3.65E+06 2.80E+06 - - - 7.0139 0.9995 221125_WJC_METTL3_EV_vs_WT_F05.13061.13061.2 0.000231 24-Oct R.IQFKPDDGISPER.A sp|Q96I24|FUBP3_HUMAN 1 1500.7573 2.34 65012 13061 2 1500.759851 751.3859 Far upstream element-binding protein 3 OS=Homo sapiens OX=9606 GN=FUBP3 PE=1 SV=2 4.56 2470 - 389265 - - - 1.7278 - 2.161 0.384 - 228.1 1 2 0 0.0026 13 0 0 0 7.57E+07 3.23E+07 - - - 3.8541 0.9999 221125_WJC_METTL3_EV_vs_WT_F05.13062.13062.3 0.000245 Nov-36 R.K[136.11]IQEILTQVK[136.11].Q sp|O00425|IF2B3_HUMAN 1 1214.7569 1.58 65013 13062 3 1214.757135 405.9263 Insulin-like growth factor 2 mRNA-binding protein 3 OS=Homo sapiens OX=9606 GN=IGF2BP3 PE=1 SV=2 8.59 2470.1 - 388978 - - - 0.1737 - 2.183 0.393 - 142.4 1 2 0 0.0002 10 0 0 0 8.93E+06 5.67E+06 - - - 5.2015 0.9998 221125_WJC_METTL3_EV_vs_WT_F05.13063.13063.2 8.05E-06 20-Dec R.QNLSQFEAQAR.K "sp|Q8N684|CPSF7_HUMAN,tr|F5H047|F5H047_HUMAN,tr|F5H669|F5H669_HUMAN,tr|F5H6M0|F5H6M0_HUMAN,tr|J3QT54|J3QT54_HUMAN" 5 1290.6317 1.36 65014 13063 2 1290.634338 646.3231 Cleavage and polyadenylation specificity factor subunit 7 OS=Homo sapiens OX=9606 GN=CPSF7 PE=1 SV=1 6 2470.2 - 320270 - - - 2.0726 - 2.372 0.568 - 684.5 1 2 0 0.0027 11 0 0 0 6.92E+06 5.07E+06 - - - 5.572 1 221125_WJC_METTL3_EV_vs_WT_F05.13064.13064.2 1.43E-05 15/24 R.LQQQLTQAQETLK.S "sp|Q9Y4P3|TBL2_HUMAN,tr|E9PF19|E9PF19_HUMAN" 2 1527.8257 1.38 65015 13064 2 1527.826847 764.9201 Transducin beta-like protein 2 OS=Homo sapiens OX=9606 GN=TBL2 PE=1 SV=1 6 2470.4 - 284505 - - - 0.7697 - 3.205 0.506 - 971.9 1 2 0 0.0012 13 0 0 0 2.54E+06 1.85E+06 - - - 5.7672 0.9996 221125_WJC_METTL3_EV_vs_WT_F05.13065.13065.2 0.0297 24-Oct R.LQQQLTQAQETLK[136.11].S "sp|Q9Y4P3|TBL2_HUMAN,tr|E9PF19|E9PF19_HUMAN" 2 1535.8399 1.38 65016 13065 2 1535.842319 768.9272 Transducin beta-like protein 2 OS=Homo sapiens OX=9606 GN=TBL2 PE=1 SV=1 6 2470.5 - 265970 - - - 1.5939 - 2.594 0.32 - 355.4 1 2 0 0.0024 13 0 0 0 2.54E+06 1.85E+06 - - - 3.8502 0.9997 221125_WJC_METTL3_EV_vs_WT_F05.13066.13066.2 1.12E-06 20-Oct R.QNLSQFEAQAR[166.11].K "sp|Q8N684|CPSF7_HUMAN,tr|F5H047|F5H047_HUMAN,tr|F5H669|F5H669_HUMAN,tr|F5H6M0|F5H6M0_HUMAN,tr|J3QT54|J3QT54_HUMAN" 5 1300.6399 1.36 65017 13066 2 1300.642827 651.3272 Cleavage and polyadenylation specificity factor subunit 7 OS=Homo sapiens OX=9606 GN=CPSF7 PE=1 SV=1 6 2470.6 - 250943 - - - 2.2251 - 2.301 0.545 - 467.2 1 2 0 0.0029 11 0 0 0 6.92E+06 5.07E+06 - - - 5.3199 0.9998 221125_WJC_METTL3_EV_vs_WT_F05.13067.13067.3 0.000127 Nov-60 R.AEVEALHSSGMTAVVK.F sp|Q9H7E2|TDRD3_HUMAN 1 1627.824 -1 65018 13067 3 1627.822865 543.6153 Tudor domain-containing protein 3 OS=Homo sapiens OX=9606 GN=TDRD3 PE=1 SV=1 5.4 2470.7 - 248418 - - - -0.6708 - 2.234 0.343 - 117.1 1 2 0 -0.0011 16 0 0 0 0.00E+00 0.00E+00 - - - 4.4262 0.9912 221125_WJC_METTL3_EV_vs_WT_F05.13069.13069.3 0.0325 Sep-52 R.AFSSLHGFQSAGER.G tr|C9JGE3|C9JGE3_HUMAN 1 1492.7059 1.66 65020 13069 3 1492.708548 498.5759 EWS RNA-binding protein variant 6 OS=Homo sapiens OX=9606 GN=EWSR1 PE=1 SV=2 6.79 2471 - 188068 - - - 1.78 - 1.427 0.244 - 52.7 1 2 0 0.0027 14 0 0 0 6.47E+05 3.89E+05 - - - 2.2046 0.9986 221125_WJC_METTL3_EV_vs_WT_F05.13072.13072.3 0.00647 Nov-36 R.RIDISPSTLR.K "sp|Q9NYF8|BCLF1_HUMAN,tr|E9PKI6|E9PKI6_HUMAN,tr|A0A1W2PQ43|A0A1W2PQ43_HUMAN,tr|E9PK91|E9PK91_HUMAN,tr|E9PK09|E9PK09_HUMAN,tr|E9PQN2|E9PQN2_HUMAN" 6 1156.6564 2.68 65022 13072 3 1156.654843 386.5594 Bcl-2-associated transcription factor 1 OS=Homo sapiens OX=9606 GN=BCLAF1 PE=1 SV=2 9.6 2471.4 - 984665 - - - -1.3643 - 1.701 0.278 - 252 1 2 0 -0.0016 10 0 0 0 8.87E+06 3.30E+06 - - - 3.1904 0.9909 221125_WJC_METTL3_EV_vs_WT_F05.13073.13073.2 0.000268 Oct-32 R.TPAEASSTGQTGPQSAL.- "sp|Q9Y676|RT18B_HUMAN,tr|A0A0G2JIC6|A0A0G2JIC6_HUMAN" 2 1601.7533 - 65023 13073 2 1601.764254 801.8839 "28S ribosomal protein S18b, mitochondrial OS=Homo sapiens OX=9606 GN=MRPS18B PE=1 SV=1" 4 2471.6 - 316019 - - - 6.8425 - 1.972 0.523 - 211.7 1 2 0 0.011 17 0 0 0 - - - - - 4.5699 1 221125_WJC_METTL3_EV_vs_WT_F05.13074.13074.2 3.36E-07 15/24 K.QTLQSEQPLQVAR[166.11].C "sp|P35998|PRS7_HUMAN,tr|C9JX88|C9JX88_HUMAN,tr|C9JLS9|C9JLS9_HUMAN" 3 1506.803 0.57 65024 13074 2 1506.803246 754.4088 26S proteasome regulatory subunit 7 OS=Homo sapiens OX=9606 GN=PSMC2 PE=1 SV=3 6 2471.7 - 1.04E+06 - - - 0.1792 - 3.092 0.524 - 711.9 1 2 0 0.0003 13 0 0 0 4.17E+06 7.28E+06 - - - 5.8083 0.9874 221125_WJC_METTL3_EV_vs_WT_F05.13075.13075.3 0.0079 Nov-44 K.LPDLKDAEAVQK.F sp|Q15388|TOM20_HUMAN 1 1325.7191 1.52 65025 13075 3 1325.718994 442.9136 Mitochondrial import receptor subunit TOM20 homolog OS=Homo sapiens OX=9606 GN=TOMM20 PE=1 SV=1 4.56 2471.8 - 961824 - - - -0.0656 - 1.624 0.245 - 116.8 1 2 1 -0.0001 12 0 0 0 2.81E+07 1.84E+07 - - - 2.6155 0.9999 221125_WJC_METTL3_EV_vs_WT_F05.13076.13076.2 7.46E-05 16/18 R.KIQEILTQVK.Q sp|O00425|IF2B3_HUMAN 1 1198.7285 1.66 65026 13076 2 1198.728614 600.3715 Insulin-like growth factor 2 mRNA-binding protein 3 OS=Homo sapiens OX=9606 GN=IGF2BP3 PE=1 SV=2 8.59 2471.9 - 912310 - - - 0.0751 - 3.096 0.442 - 924.2 1 2 0 0.0001 10 0 0 0 1.02E+07 6.12E+06 - - - 5.4601 0.9999 221125_WJC_METTL3_EV_vs_WT_F05.13077.13077.2 9.76E-07 13/24 R.IQFK[136.11]PDDGISPER[166.11].A sp|Q96I24|FUBP3_HUMAN 1 1518.7797 2.33 65027 13077 2 1518.779331 760.3971 Far upstream element-binding protein 3 OS=Homo sapiens OX=9606 GN=FUBP3 PE=1 SV=2 4.56 2472 - 881568 - - - -0.2614 - 2.325 0.527 - 437.9 1 2 0 -0.0004 13 0 0 0 7.55E+07 3.23E+07 - - - 5.0987 0.996 221125_WJC_METTL3_EV_vs_WT_F05.13079.13079.3 0.0121 Sep-40 R.VATWFNQPARK.L "sp|P26373|RL13_HUMAN,tr|H3BTH3|H3BTH3_HUMAN,tr|J3QSB4|J3QSB4_HUMAN" 3 1316.699 0.58 65029 13079 3 1316.698514 439.9069 60S ribosomal protein L13 OS=Homo sapiens OX=9606 GN=RPL13 PE=1 SV=4 11 2472.3 - 700768 - - - -0.3349 - 1.908 0.179 - 142 1 2 0 -0.0004 11 0 0 0 4.87E+06 8.35E+06 - - - 2.3709 0.9978 221125_WJC_METTL3_EV_vs_WT_F05.13081.13081.3 3.01E-07 17/68 C.LSGAPQASAADVVVVHGR.R "sp|P09110|THIK_HUMAN,tr|B4DVF4|B4DVF4_HUMAN,tr|F2Z3P7|F2Z3P7_HUMAN,tr|C9JDE9|C9JDE9_HUMAN,tr|F2Z2Q6|F2Z2Q6_HUMAN" 5 1732.922 1.1 65031 13081 3 1732.923464 578.648 "3-ketoacyl-CoA thiolase, peroxisomal OS=Homo sapiens OX=9606 GN=ACAA1 PE=1 SV=2" 6.74 2472.5 - 544303 - - - 0.8269 - 2.931 0.52 - 202 1 1 0 0.0014 18 0 0 0 2.19E+06 2.00E+06 - - - 7.0148 1 221125_WJC_METTL3_EV_vs_WT_F05.13083.13083.2 4.95E-10 28-Dec A.MSTLPVEDEESSESR[166.11].M "sp|P78347|GTF2I_HUMAN,tr|C9J6M0|C9J6M0_HUMAN,tr|A0A494C1K3|A0A494C1K3_HUMAN" 3 1704.7388 1.42 65033 13083 2 1704.73795 853.3767 General transcription factor II-I OS=Homo sapiens OX=9606 GN=GTF2I PE=1 SV=2 3.91 2472.8 - 489783 - - - -0.4869 - 2.364 0.677 - 225.1 1 1 0 -0.0008 15 0 0 0 7.46E+06 5.26E+06 - - - 6.1563 0.9902 221125_WJC_METTL3_EV_vs_WT_F05.13090.13090.2 0.000145 20-Oct Q.FKPDDGISPER.A sp|Q96I24|FUBP3_HUMAN 1 1259.6146 1.28 65040 13090 2 1259.61626 630.8146 Far upstream element-binding protein 3 OS=Homo sapiens OX=9606 GN=FUBP3 PE=1 SV=2 4.56 2473.7 - 194750 - - - 1.3052 - 2.007 0.565 - 218.9 1 1 0 0.0016 11 0 0 0 1.06E+07 8.30E+06 - - - 5.0982 0.9999 221125_WJC_METTL3_EV_vs_WT_F05.13091.13091.2 3.79E-07 24-Aug R.DPSQIDNNEPYMK.L "sp|Q13347|EIF3I_HUMAN,tr|A0A7I2YQT9|A0A7I2YQT9_HUMAN,tr|A0A7I2V613|A0A7I2V613_HUMAN,tr|A0A7I2V3N2|A0A7I2V3N2_HUMAN,tr|A0A7I2YQI6|A0A7I2YQI6_HUMAN,tr|A0A7I2YQF8|A0A7I2YQF8_HUMAN,tr|Q5TFK1|Q5TFK1_HUMAN,tr|A0A7I2V3U3|A0A7I2V3U3_HUMAN,tr|A0A7I2V607|A0A7I2V607_HUMAN,tr|A0A7I2V640|A0A7I2V640_HUMAN,tr|A0A7P0MRT9|A0A7P0MRT9_HUMAN,tr|A0A7I2V3K6|A0A7I2V3K6_HUMAN,tr|A0A7I2V4S8|A0A7I2V4S8_HUMAN,tr|A0A7I2V2M3|A0A7I2V2M3_HUMAN,tr|A0A7I2YQI2|A0A7I2YQI2_HUMAN,tr|A0A7I2YQC8|A0A7I2YQC8_HUMAN,tr|A0A7I2V685|A0A7I2V685_HUMAN" 17 1549.6719 0.3 65041 13091 2 1549.671335 775.8432 Eukaryotic translation initiation factor 3 subunit I OS=Homo sapiens OX=9606 GN=EIF3I PE=1 SV=1 4.03 2473.8 - 130477 - - - -0.3472 - 1.815 0.623 - 181.9 1 2 0 -0.0005 13 0 0 0 5.48E+05 1.82E+06 - - - 5.1722 0.9999 221125_WJC_METTL3_EV_vs_WT_F05.13093.13093.2 4.21E-05 22-Dec R.AQVQEFC[160.03]DYGTK[136.11].E "sp|Q86U44|MTA70_HUMAN,tr|H0YFV6|H0YFV6_HUMAN" 2 1452.6435 0.01 65042 13093 2 1452.643486 727.329 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 4.37 2474 - 5.63E+06 - - - 0.0041 - 2.64 0.55 - 463.2 1 2 0 0 12 0 0 0 1.06E+06 7.65E+07 - - - 5.6576 0.9996 221125_WJC_METTL3_EV_vs_WT_F05.13097.13097.3 8.99E-05 Dec-52 K.FELSENC[160.03]SERPGLR.G "sp|Q14203|DCTN1_HUMAN,tr|A0A804CDA6|A0A804CDA6_HUMAN,tr|E7EX90|E7EX90_HUMAN,tr|A0A7P0Z4C3|A0A7P0Z4C3_HUMAN,tr|Q6AWB1|Q6AWB1_HUMAN" 5 1692.789 1.88 65045 13097 3 1692.787734 565.2703 Dynactin subunit 1 OS=Homo sapiens OX=9606 GN=DCTN1 PE=1 SV=3 4.79 2474.4 - 3.38E+06 - - - -0.7296 - 2.28 0.292 - 172.1 1 2 0 -0.0012 14 0 0 0 1.03E+08 5.52E+07 - - - 3.9854 1 221125_WJC_METTL3_EV_vs_WT_F05.13098.13098.2 6.35E-07 15/26 K.DVNLASC[160.03]AADGSVK.L sp|O43172|PRP4_HUMAN 1 1405.6507 2.86 65046 13098 2 1405.647631 703.8326 U4\U6 small nuclear ribonucleoprotein Prp4 OS=Homo sapiens OX=9606 GN=PRPF4 PE=1 SV=2 4.21 2474.4 - 2.92E+06 - - - -2.2146 - 3.033 0.649 - 814.8 1 2 0 -0.0031 14 0 0 0 9.15E+07 3.19E+07 - - - 6.6179 0.9998 221125_WJC_METTL3_EV_vs_WT_F05.13099.13099.3 0.00139 Nov-52 K.FELSENC[160.03]SER[166.11]PGLR[166.11].G "sp|Q14203|DCTN1_HUMAN,tr|A0A804CDA6|A0A804CDA6_HUMAN,tr|E7EX90|E7EX90_HUMAN,tr|A0A7P0Z4C3|A0A7P0Z4C3_HUMAN,tr|Q6AWB1|Q6AWB1_HUMAN" 5 1712.8055 1.88 65047 13099 3 1712.804872 571.9424 Dynactin subunit 1 OS=Homo sapiens OX=9606 GN=DCTN1 PE=1 SV=3 4.79 2474.5 - 2.76E+06 - - - -0.3719 - 2.088 0.386 - 140.3 1 2 0 -0.0006 14 0 0 0 1.03E+08 5.52E+07 - - - 4.7998 1 221125_WJC_METTL3_EV_vs_WT_F05.13100.13100.3 0.000217 14/44 R.ELQNTVANLHVR.Q "sp|O15127|SCAM2_HUMAN,tr|H3BN93|H3BN93_HUMAN,tr|H3BPL9|H3BPL9_HUMAN,tr|H3BUB6|H3BUB6_HUMAN,tr|H3BV04|H3BV04_HUMAN" 5 1392.7474 1.16 65048 13100 3 1392.746468 465.2564 Secretory carrier-associated membrane protein 2 OS=Homo sapiens OX=9606 GN=SCAMP2 PE=1 SV=2 6.85 2474.5 - 2.18E+06 - - - -0.6412 - 2.472 0.487 - 333.5 1 2 0 -0.0009 12 0 0 0 1.37E+07 1.18E+07 - - - 6.4779 0.9995 221125_WJC_METTL3_EV_vs_WT_F05.13101.13101.3 0.00837 Dec-36 R.KIQEILTQVK.Q sp|O00425|IF2B3_HUMAN 1 1198.7285 1.59 65049 13101 3 1198.727387 400.5835 Insulin-like growth factor 2 mRNA-binding protein 3 OS=Homo sapiens OX=9606 GN=IGF2BP3 PE=1 SV=2 8.59 2474.6 - 2.09E+06 - - - -0.9485 - 2.023 0.285 - 196.1 1 2 0 -0.0011 10 0 0 0 8.96E+06 5.64E+06 - - - 3.7748 0.9999 221125_WJC_METTL3_EV_vs_WT_F05.13102.13102.3 0.00284 Nov-44 R.ELQNTVANLHVR[166.11].Q "sp|O15127|SCAM2_HUMAN,tr|H3BN93|H3BN93_HUMAN,tr|H3BPL9|H3BPL9_HUMAN,tr|H3BUB6|H3BUB6_HUMAN,tr|H3BV04|H3BV04_HUMAN" 5 1402.7556 1.24 65050 13102 3 1402.757324 468.5925 Secretory carrier-associated membrane protein 2 OS=Homo sapiens OX=9606 GN=SCAMP2 PE=1 SV=2 6.85 2474.6 - 1.92E+06 - - - 1.2069 - 2.285 0.39 - 197.5 1 2 0 0.0017 12 0 0 0 1.32E+07 1.06E+07 - - - 5.1782 1 221125_WJC_METTL3_EV_vs_WT_F05.13107.13107.2 4.68E-07 17/26 K.DVNLASC[160.03]AADGSVK[136.11].L sp|O43172|PRP4_HUMAN 1 1413.6649 2.86 65055 13107 2 1413.662293 707.8397 U4\U6 small nuclear ribonucleoprotein Prp4 OS=Homo sapiens OX=9606 GN=PRPF4 PE=1 SV=2 4.21 2475 - 1.18E+06 - - - -1.8753 - 2.945 0.552 - 1121.1 1 2 0 -0.0027 14 0 0 0 9.15E+07 3.19E+07 - - - 5.8277 0.9932 221125_WJC_METTL3_EV_vs_WT_F05.13108.13108.3 0.00117 14/44 R.NR[166.11]LEEVSPNLVR[166.11].Y "sp|P28331|NDUS1_HUMAN,tr|B4DJ81|B4DJ81_HUMAN" 2 1444.7901 1.29 65056 13108 3 1444.78831 482.604 "NADH-ubiquinone oxidoreductase 75 kDa subunit, mitochondrial OS=Homo sapiens OX=9606 GN=NDUFS1 PE=1 SV=3" 6.14 2475.1 - 1.15E+06 - - - -1.25 - 2.508 0.182 - 426 1 2 1 -0.0018 12 0 0 0 9.05E+06 7.00E+06 - - - 3.1173 0.9998 221125_WJC_METTL3_EV_vs_WT_F05.13109.13109.3 0.000537 13/44 R.NRLEEVSPNLVR.Y "sp|P28331|NDUS1_HUMAN,tr|B4DJ81|B4DJ81_HUMAN" 2 1424.7736 1.29 65057 13109 3 1424.773972 475.9318 "NADH-ubiquinone oxidoreductase 75 kDa subunit, mitochondrial OS=Homo sapiens OX=9606 GN=NDUFS1 PE=1 SV=3" 6.14 2475.2 - 1.13E+06 - - - 0.2779 - 2.804 0.402 - 286.3 1 2 1 0.0004 12 0 0 0 9.05E+06 7.00E+06 - - - 5.8797 0.999 221125_WJC_METTL3_EV_vs_WT_F05.13112.13112.3 0.0129 13/32 K.QR[166.11]EFEEYIR[166.11].D "sp|O14776|TCRG1_HUMAN,tr|A0A7P0T8N8|A0A7P0T8N8_HUMAN,tr|G3V220|G3V220_HUMAN" 3 1288.6315 0.53 65060 13112 3 1288.630676 430.5511 Transcription elongation regulator 1 OS=Homo sapiens OX=9606 GN=TCERG1 PE=1 SV=2 4.79 2475.5 - 547473 - - - -0.6317 - 1.966 0.349 - 281 1 2 1 -0.0008 9 0 0 0 2.59E+06 4.88E+06 - - - 4.4681 0.9929 221125_WJC_METTL3_EV_vs_WT_F05.13117.13117.2 0.0043 26-Sep K.SPSDSGYSYETIGK.T sp|P46821|MAP1B_HUMAN 1 1489.6573 1.44 65064 13117 2 1489.651407 745.8359 Microtubule-associated protein 1B OS=Homo sapiens OX=9606 GN=MAP1B PE=1 SV=2 4.37 2476.3 - 341051 - - - -3.9351 - 1.378 0.368 - 165.1 1 2 0 -0.0059 14 0 0 0 1.49E+06 1.04E+06 - - - 2.5618 0.9845 221125_WJC_METTL3_EV_vs_WT_F05.13119.13119.2 0.000218 22-Oct L.QFKPDDGISPER.A sp|Q96I24|FUBP3_HUMAN 1 1387.6732 19.49 65066 13119 2 1387.674508 694.8439 Far upstream element-binding protein 3 OS=Homo sapiens OX=9606 GN=FUBP3 PE=1 SV=2 4.56 2476.4 - 1.16E+06 - - - 0.9476 - 1.83 0.465 - 270.2 1 1 0 0.0013 12 0 0 0 1.37E+07 7.03E+05 - - - 4.0651 1 221125_WJC_METTL3_EV_vs_WT_F05.13123.13123.2 4.14E-08 14/26 R.QGQGQLVTC[160.03]SGAFK[136.11].E "sp|Q16531|DDB1_HUMAN,tr|F5GWI0|F5GWI0_HUMAN,tr|A0A7P0TAK7|A0A7P0TAK7_HUMAN,tr|A0A7P0T870|A0A7P0T870_HUMAN,tr|A0A7P0TB30|A0A7P0TB30_HUMAN,tr|A0A7P0Z3Z5|A0A7P0Z3Z5_HUMAN,tr|F5GY55|F5GY55_HUMAN,tr|A0A7P0Z4B9|A0A7P0Z4B9_HUMAN,tr|A0A7P0T965|A0A7P0T965_HUMAN" 9 1487.7282 0.54 65070 13123 2 1487.735691 744.8714 DNA damage-binding protein 1 OS=Homo sapiens OX=9606 GN=DDB1 PE=1 SV=1 8.22 2476.9 - 341051 - - - 5.0265 - 2.797 0.626 - 818.7 1 2 0 0.0075 14 0 0 0 4.28E+06 7.97E+06 - - - 6.2434 0.8842 221125_WJC_METTL3_EV_vs_WT_F05.13124.13124.2 1.40E-07 13/30 A.SSLVSGLNSSASEPAK[136.11].E "sp|Q86U44|MTA70_HUMAN,tr|F5H6D8|F5H6D8_HUMAN,tr|H0YFV6|H0YFV6_HUMAN,tr|B4DTN4|B4DTN4_HUMAN" 4 1540.7824 0.001 65071 13124 2 1540.774112 771.3985 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 5.72 2477.1 - 324883 - - - -5.3895 - 2.675 0.559 - 383.9 1 1 0 -0.0083 16 0 0 0 0.00E+00 2.84E+06 - - - 5.5863 1 221125_WJC_METTL3_EV_vs_WT_F05.13125.13125.2 1.60E-07 26-Dec R.QGQGQLVTC[160.03]SGAFK.E "sp|Q16531|DDB1_HUMAN,tr|F5GWI0|F5GWI0_HUMAN,tr|A0A7P0TAK7|A0A7P0TAK7_HUMAN,tr|A0A7P0T870|A0A7P0T870_HUMAN,tr|A0A7P0TB30|A0A7P0TB30_HUMAN,tr|A0A7P0Z3Z5|A0A7P0Z3Z5_HUMAN,tr|F5GY55|F5GY55_HUMAN,tr|A0A7P0Z4B9|A0A7P0Z4B9_HUMAN,tr|A0A7P0T965|A0A7P0T965_HUMAN" 9 1479.714 0.54 65072 13125 2 1479.710445 740.8643 DNA damage-binding protein 1 OS=Homo sapiens OX=9606 GN=DDB1 PE=1 SV=1 8.22 2477.2 - 308790 - - - -2.4113 - 2.558 0.63 - 484.3 1 2 0 -0.0036 14 0 0 0 4.28E+06 7.97E+06 - - - 6.05 1 221125_WJC_METTL3_EV_vs_WT_F05.13134.13134.3 9.63E-13 19/60 K.MGAMAKPDC[160.03]IITC[160.03]DGK.N "sp|Q01469|FABP5_HUMAN,tr|I6L8B7|I6L8B7_HUMAN" 2 1766.7824 3.27 65079 13134 3 1766.781441 589.9347 Fatty acid-binding protein 5 OS=Homo sapiens OX=9606 GN=FABP5 PE=1 SV=3 5.71 2478.4 - 1.09E+06 - - - -0.5252 - 3.742 0.698 - 436.1 1 2 0 -0.0009 16 0 0 0 1.01E+07 3.07E+06 - - - 9.7077 1 221125_WJC_METTL3_EV_vs_WT_F05.13136.13136.2 1.64E-07 14/24 K.TTFQENTQSISVR.G "sp|A6NHR9|SMHD1_HUMAN,tr|J3KTL8|J3KTL8_HUMAN" 2 1509.7423 999 65081 13136 2 1509.741234 755.8784 Structural maintenance of chromosomes flexible hinge domain-containing protein 1 OS=Homo sapiens OX=9606 GN=SMCHD1 PE=1 SV=2 5.66 2478.6 - 994555 - - - -0.7299 - 2.612 0.618 - 716.1 1 2 0 -0.0011 13 0 0 0 8.70E+06 0.00E+00 - - - 6.0694 0.9978 221125_WJC_METTL3_EV_vs_WT_F05.13137.13137.3 0.0555 Nov-48 R.IQFKPDDGISPER[166.11].A sp|Q96I24|FUBP3_HUMAN 1 1510.7655 - 65082 13137 3 1510.761531 504.5958 Far upstream element-binding protein 3 OS=Homo sapiens OX=9606 GN=FUBP3 PE=1 SV=2 4.56 2478.6 - 913068 - - - -2.6457 - 2.035 0.273 - 152.9 1 2 0 -0.004 13 0 0 0 - - - - - 3.5089 0.9988 221125_WJC_METTL3_EV_vs_WT_F05.13139.13139.4 0.000269 14/72 R.YIATITDKELLKK.C "sp|Q8IWZ3|ANKH1_HUMAN,tr|E9PDP5|E9PDP5_HUMAN,tr|H3BLS9|H3BLS9_HUMAN,tr|H0Y4P6|H0Y4P6_HUMAN,tr|H7C2F5|H7C2F5_HUMAN" 5 1534.897 1.3 65084 13139 4 1534.894831 384.7315 Ankyrin repeat and KH domain-containing protein 1 OS=Homo sapiens OX=9606 GN=ANKHD1 PE=1 SV=1 8.43 2478.8 - 873090 - - - -1.4431 - 2.455 0.349 - 106.5 1 2 1 -0.0022 13 0 0 0 8.90E+06 6.86E+06 - - - 2.5961 0.9994 221125_WJC_METTL3_EV_vs_WT_F05.13140.13140.3 0.00638 Dec-32 K.STWLILHHK[136.11].V sp|P00167|CYB5_HUMAN 1 1141.6488 0.001 65085 13140 3 1141.647837 381.5569 Cytochrome b5 OS=Homo sapiens OX=9606 GN=CYB5A PE=1 SV=2 8.51 2479 - 729009 - - - -0.8111 - 1.989 0.275 - 155.6 1 2 0 -0.0009 9 0 0 0 0.00E+00 6.46E+06 - - - 3.6781 0.9944 221125_WJC_METTL3_EV_vs_WT_F05.13141.13141.3 0.00948 Nov-40 K.AK[136.11]QDVIEVIEK[136.11].A "sp|P24928|RPB1_HUMAN,tr|A0A6Q8PGB0|A0A6Q8PGB0_HUMAN" 2 1286.7417 1.39 65086 13141 3 1286.738713 429.9212 DNA-directed RNA polymerase II subunit RPB1 OS=Homo sapiens OX=9606 GN=POLR2A PE=1 SV=2 4.68 2479.1 - 588718 - - - -2.2957 - 2.042 0.286 - 181.9 1 2 1 -0.003 11 0 0 0 5.35E+06 3.85E+06 - - - 3.756 0.9966 221125_WJC_METTL3_EV_vs_WT_F05.13142.13142.2 0.0778 26-Jul K.FELSENC[160.03]SERPGLR.G "sp|Q14203|DCTN1_HUMAN,tr|A0A804CDA6|A0A804CDA6_HUMAN,tr|E7EX90|E7EX90_HUMAN,tr|A0A7P0Z4C3|A0A7P0Z4C3_HUMAN,tr|Q6AWB1|Q6AWB1_HUMAN" 5 1692.789 1.87 65087 13142 2 1692.785994 847.4018 Dynactin subunit 1 OS=Homo sapiens OX=9606 GN=DCTN1 PE=1 SV=3 4.79 2479.2 - 583479 - - - -1.7575 - 1.337 0.281 - 43.5 1 2 0 -0.003 14 0 0 0 3.13E+06 1.68E+06 - - - 1.8443 0.985 221125_WJC_METTL3_EV_vs_WT_F05.13143.13143.3 0.00325 Nov-52 R.ALEEEQEAREELER.Q "sp|Q7Z406|MYH14_HUMAN,tr|A1L2Z2|A1L2Z2_HUMAN" 2 1729.8119 2.19 65088 13143 3 1729.812859 577.6112 Myosin-14 OS=Homo sapiens OX=9606 GN=MYH14 PE=1 SV=2 4.12 2479.4 - 454208 - - - 0.5706 - 1.807 0.214 - 162.1 1 2 1 0.001 14 0 0 0 3.22E+06 1.47E+06 - - - 2.498 0.9904 221125_WJC_METTL3_EV_vs_WT_F05.13147.13147.3 0.0843 Aug-40 K.K[136.11]ADIGLPYPQR[166.11].V sp|Q8IYH5|ZZZ3_HUMAN 1 1274.7102 1.18 65092 13147 3 1274.706065 425.9107 ZZ-type zinc finger-containing protein 3 OS=Homo sapiens OX=9606 GN=ZZZ3 PE=1 SV=1 8.59 2479.9 - 221033 - - - -3.2368 - 1.629 0.268 - 111.5 2 2 0 -0.0041 11 0 0 0 3.82E+06 3.24E+06 - - - 2.7737 0.9591 221125_WJC_METTL3_EV_vs_WT_F05.13149.13149.2 0.00566 30-Sep K.PAVAPPAPPSSSQLC[160.03]R.Y "sp|Q6PJT7|ZC3HE_HUMAN,tr|G3V256|G3V256_HUMAN,tr|G3V411|G3V411_HUMAN" 3 1633.8246 1.41 65094 13149 2 1633.826009 817.9196 Zinc finger CCCH domain-containing protein 14 OS=Homo sapiens OX=9606 GN=ZC3H14 PE=1 SV=1 8.68 2480.1 - 238716 - - - 0.8465 - 1.789 0.327 - 199.3 1 1 0 0.0014 16 0 0 0 2.51E+06 1.78E+06 - - - 2.8858 0.9997 221125_WJC_METTL3_EV_vs_WT_F05.13150.13150.2 3.80E-06 28-Dec K.ALESISSDQQSEMVK[136.11].E tr|A0A0C4DG68|A0A0C4DG68_HUMAN 1 1658.7913 1.51 65095 13150 2 1658.787175 830.4029 Pumilio homolog 2 (Fragment) OS=Homo sapiens OX=9606 GN=PUM2 PE=1 SV=1 4.14 2480.3 - 0 - - - -2.4663 - 2.562 0.523 - 372.9 1 2 0 -0.0041 15 0 0 0 2.65E+06 1.75E+06 - - - 5.2156 0.9992 221125_WJC_METTL3_EV_vs_WT_F05.13153.13153.3 5.73E-05 14/44 K.LPDLK[136.11]DAEAVQK[136.11].F sp|Q15388|TOM20_HUMAN 1 1341.7475 1.67 65096 13153 3 1341.741709 448.2564 Mitochondrial import receptor subunit TOM20 homolog OS=Homo sapiens OX=9606 GN=TOMM20 PE=1 SV=1 4.56 2480.7 - 1.62E+06 - - - -4.3019 - 2.767 0.518 - 270 1 2 1 -0.0058 12 0 0 0 2.68E+07 1.61E+07 - - - 7.1347 1 221125_WJC_METTL3_EV_vs_WT_F05.13154.13154.3 1.60E-09 17/44 K.IHEEFSEHALLR.K "sp|Q9Y2L1|RRP44_HUMAN,tr|G3V1J5|G3V1J5_HUMAN" 2 1479.747 1.28 65097 13154 3 1479.743038 494.2563 Exosome complex exonuclease RRP44 OS=Homo sapiens OX=9606 GN=DIS3 PE=1 SV=2 5.33 2480.7 - 1.70E+06 - - - -2.6957 - 3.204 0.613 - 398 1 2 0 -0.004 12 0 0 0 1.38E+07 1.07E+07 - - - 8.6008 1 221125_WJC_METTL3_EV_vs_WT_F05.13155.13155.3 1.03E-07 Oct-44 R.TAAENDFVVLKK.D sp|P19013|K2C4_HUMAN 1 1333.7242 0.13 65098 13155 3 1333.72211 445.582 "Keratin, type II cytoskeletal 4 OS=Homo sapiens OX=9606 GN=KRT4 PE=1 SV=5" 5.73 2480.8 - 1.29E+06 - - - -1.5415 - 2.267 0.563 - 115.1 1 2 0 -0.0021 12 0 0 0 7.61E+06 5.96E+07 - - - 7.085 0.9933 221125_WJC_METTL3_EV_vs_WT_F05.13156.13156.3 0.0585 Nov-48 R.EAAAALVEEETR[166.11]R[166.11].Y sp|O75934|SPF27_HUMAN 1 1463.7483 1.12 65099 13156 3 1463.752759 488.9234 Pre-mRNA-splicing factor SPF27 OS=Homo sapiens OX=9606 GN=BCAS2 PE=1 SV=1 4.49 2480.9 - 1.10E+06 - - - 3.0388 - 1.806 0.251 - 84.4 1 2 0 0.0044 13 0 0 0 8.99E+06 7.99E+06 - - - 2.9399 0.9994 221125_WJC_METTL3_EV_vs_WT_F05.13157.13157.3 0.00558 14/48 R.LFTSDLQDK[136.11]NEYK[136.11].V "sp|Q8NFH4|NUP37_HUMAN,tr|F8VTY2|F8VTY2_HUMAN" 2 1615.8065 1.33 65100 13157 3 1615.802622 539.6094 Nucleoporin Nup37 OS=Homo sapiens OX=9606 GN=NUP37 PE=1 SV=1 4.56 2481 - 875073 - - - -2.371 - 2.816 0.405 - 178.8 1 2 1 -0.0038 13 0 0 0 5.96E+06 4.50E+06 - - - 5.8613 1 221125_WJC_METTL3_EV_vs_WT_F05.13161.13161.3 3.12E-12 14/60 R.QPPLLGDHPAEYGEGR.G tr|A0A3B3ITJ4|A0A3B3ITJ4_HUMAN 1 1734.8325 1.4 65104 13161 3 1734.829301 579.2848 Heterogeneous nuclear ribonucleoprotein L (Fragment) OS=Homo sapiens OX=9606 GN=HNRNPL PE=1 SV=1 4.65 2481.5 - 448070 - - - -1.8717 - 3.178 0.645 - 184.9 1 2 0 -0.0032 16 0 0 0 2.66E+07 1.90E+07 - - - 8.697 1 221125_WJC_METTL3_EV_vs_WT_F05.13162.13162.3 1.75E-07 14/60 R.QPPLLGDHPAEYGEGR[166.11].G tr|A0A3B3ITJ4|A0A3B3ITJ4_HUMAN 1 1744.8408 1.4 65105 13162 3 1744.838382 582.6209 Heterogeneous nuclear ribonucleoprotein L (Fragment) OS=Homo sapiens OX=9606 GN=HNRNPL PE=1 SV=1 4.65 2481.6 - 444287 - - - -1.3961 - 2.975 0.617 - 255.4 1 2 0 -0.0024 16 0 0 0 2.66E+07 1.90E+07 - - - 8.2157 1 221125_WJC_METTL3_EV_vs_WT_F05.13163.13163.2 1.89E-09 15/28 K.ALESISSDQQSEMVK.E tr|A0A0C4DG68|A0A0C4DG68_HUMAN 1 1650.7771 1.51 65106 13163 2 1650.775428 826.3958 Pumilio homolog 2 (Fragment) OS=Homo sapiens OX=9606 GN=PUM2 PE=1 SV=1 4.14 2481.8 - 378920 - - - -0.9923 - 2.755 0.599 - 673.6 1 2 0 -0.0016 15 0 0 0 2.65E+06 1.75E+06 - - - 5.9562 1 221125_WJC_METTL3_EV_vs_WT_F05.13164.13164.2 4.62E-08 26-Nov K.QFDAGTVNYEQPTK.D sp|P52756|RBM5_HUMAN 1 1596.742 0.95 65107 13164 2 1596.744823 799.3783 RNA-binding protein 5 OS=Homo sapiens OX=9606 GN=RBM5 PE=1 SV=2 4.37 2481.9 - 309052 - - - 1.7673 - 2.348 0.635 - 279.7 1 2 0 0.0028 14 0 0 0 5.36E+06 5.62E+06 - - - 5.8722 0.9999 221125_WJC_METTL3_EV_vs_WT_F05.13167.13167.2 8.78E-06 Sep-32 K.EAAGEGPALYEDPPDQK[136.11].T "sp|P27695|APEX1_HUMAN,tr|G3V3C7|G3V3C7_HUMAN,tr|G3V5D9|G3V5D9_HUMAN,tr|G3V5M0|G3V5M0_HUMAN,tr|G3V3M6|G3V3M6_HUMAN,tr|A0A0C4DGK8|A0A0C4DGK8_HUMAN,tr|G3V3Y6|G3V3Y6_HUMAN,tr|G3V359|G3V359_HUMAN,tr|G3V5Q1|G3V5Q1_HUMAN" 9 1793.8199 0.001 65110 13167 2 1793.81893 897.9172 DNA-(apurinic or apyrimidinic site) endonuclease OS=Homo sapiens OX=9606 GN=APEX1 PE=1 SV=2 3.83 2482.3 - 261402 - - - -0.5541 - 1.981 0.532 - 111.7 1 2 0 -0.001 17 0 0 0 0.00E+00 2.48E+06 - - - 4.6507 0.998 221125_WJC_METTL3_EV_vs_WT_F05.13168.13168.2 0.000171 24-Oct R.YHTMQAAVDAVAR[166.11].V "sp|Q9BVI4|NOC4L_HUMAN,tr|F5H303|F5H303_HUMAN" 2 1441.7012 -1 65111 13168 2 1441.695234 721.8579 Nucleolar complex protein 4 homolog OS=Homo sapiens OX=9606 GN=NOC4L PE=1 SV=1 6.74 2482.4 - 344090 - - - -4.1056 - 1.892 0.462 - 256.1 1 2 0 -0.0059 13 0 0 0 0.00E+00 0.00E+00 - - - 4.088 1 221125_WJC_METTL3_EV_vs_WT_F05.13171.13171.3 5.61E-05 Dec-36 R.K[136.11]ESYSIYVYK[136.11].V "sp|Q8N257|H2B3B_HUMAN,sp|P33778|H2B1B_HUMAN,sp|Q6DN03|H2B2C_HUMAN,sp|P23527|H2B1O_HUMAN,sp|Q6DRA6|H2B2D_HUMAN,sp|Q16778|H2B2E_HUMAN,sp|P06899|H2B1J_HUMAN" 7 1294.678 1 65112 13171 3 1294.67766 432.5666 Histone H2B type 3-B OS=Homo sapiens OX=9606 GN=H2BU1 PE=1 SV=3 8.38 2482.8 - 4.06E+06 - - - -0.2657 - 2.061 0.534 - 239.1 1 2 0 -0.0003 10 0 0 0 5.91E+07 5.92E+07 - - - 6.6055 1 221125_WJC_METTL3_EV_vs_WT_F05.13172.13172.3 2.01E-06 Dec-36 R.KESYSIYVYK.V "sp|Q8N257|H2B3B_HUMAN,sp|P33778|H2B1B_HUMAN,sp|Q6DN03|H2B2C_HUMAN,sp|P23527|H2B1O_HUMAN,sp|Q6DRA6|H2B2D_HUMAN,sp|Q16778|H2B2E_HUMAN,sp|P06899|H2B1J_HUMAN" 7 1278.6496 1 65113 13172 3 1278.649448 427.2238 Histone H2B type 3-B OS=Homo sapiens OX=9606 GN=H2BU1 PE=1 SV=3 8.38 2482.9 - 3.18E+06 - - - -0.122 - 2.175 0.498 - 228.4 1 2 0 -0.0002 10 0 0 0 5.91E+07 5.92E+07 - - - 6.3614 0.8651 221125_WJC_METTL3_EV_vs_WT_F05.13174.13174.3 0.175 Sep-56 R.VQVYLHESTQDELAR[166.11].K "sp|Q13616|CUL1_HUMAN,tr|A0A590UJA0|A0A590UJA0_HUMAN,tr|A0A0C4DGX4|A0A0C4DGX4_HUMAN,tr|A0A590UJ21|A0A590UJ21_HUMAN,tr|A0A590UJ50|A0A590UJ50_HUMAN,tr|A0A590UJR3|A0A590UJR3_HUMAN,tr|A0A590UJ56|A0A590UJ56_HUMAN,tr|A0A590UK34|A0A590UK34_HUMAN" 8 1796.8932 0.48 65115 13174 3 1796.89675 599.9717 Cullin-1 OS=Homo sapiens OX=9606 GN=CUL1 PE=1 SV=2 4.65 2483 - 1.53E+06 - - - 1.9495 - 1.44 0.1 - 52.7 1 2 0 0.0035 15 0 0 0 2.73E+06 5.70E+06 - - - 0.6054 1 221125_WJC_METTL3_EV_vs_WT_F05.13177.13177.3 1.08E-07 16/60 K.GNAMVEEGHFAAEDVK.A "sp|Q13813|SPTN1_HUMAN,tr|A0A0D9SF54|A0A0D9SF54_HUMAN,tr|A0A0D9SGF6|A0A0D9SGF6_HUMAN" 3 1702.7621 1.62 65118 13177 3 1702.756945 568.5946 "Spectrin alpha chain, non-erythrocytic 1 OS=Homo sapiens OX=9606 GN=SPTAN1 PE=1 SV=3" 4.4 2483.3 - 952431 - - - -3.0186 - 3.327 0.596 - 335.3 1 2 0 -0.0051 16 0 0 0 6.51E+06 4.01E+06 - - - 8.2677 0.9575 221125_WJC_METTL3_EV_vs_WT_F05.13178.13178.3 0.0964 13/44 L.LKEAQLPVIENK.V sp|P00747|PLMN_HUMAN 1 1380.7977 18.16 65119 13178 3 1380.797649 461.2732 Plasminogen OS=Homo sapiens OX=9606 GN=PLG PE=1 SV=2 6.14 2483.4 - 920597 - - - -0.0123 - 2.424 0.384 - 245.7 1 1 1 0 12 0 0 0 6.68E+06 3.68E+05 - - - 5.2755 0.9999 221125_WJC_METTL3_EV_vs_WT_F05.13179.13179.2 9.81E-05 14/18 R.K[136.11]ESYSIYVYK[136.11].V "sp|Q8N257|H2B3B_HUMAN,sp|P33778|H2B1B_HUMAN,sp|Q6DN03|H2B2C_HUMAN,sp|P23527|H2B1O_HUMAN,sp|Q6DRA6|H2B2D_HUMAN,sp|Q16778|H2B2E_HUMAN,sp|P06899|H2B1J_HUMAN" 7 1294.678 1.33 65120 13179 2 1294.678401 648.3463 Histone H2B type 3-B OS=Homo sapiens OX=9606 GN=H2BU1 PE=1 SV=3 8.38 2483.6 - 822050 - - - 0.3066 - 2.903 0.483 - 668.4 1 2 0 0.0004 10 0 0 0 2.05E+07 1.53E+07 - - - 5.5831 0.9998 221125_WJC_METTL3_EV_vs_WT_F05.13180.13180.3 0.00114 Dec-48 R.YIATITDKELLKK.C "sp|Q8IWZ3|ANKH1_HUMAN,tr|E9PDP5|E9PDP5_HUMAN,tr|H3BLS9|H3BLS9_HUMAN,tr|H0Y4P6|H0Y4P6_HUMAN,tr|H7C2F5|H7C2F5_HUMAN" 5 1534.897 1.02 65121 13180 3 1534.896458 512.6396 Ankyrin repeat and KH domain-containing protein 1 OS=Homo sapiens OX=9606 GN=ANKHD1 PE=1 SV=1 8.43 2483.7 - 782353 - - - -0.3831 - 2.39 0.451 - 99.7 1 2 1 -0.0006 13 0 0 0 6.66E+06 6.56E+06 - - - 5.9304 1 221125_WJC_METTL3_EV_vs_WT_F05.13181.13181.2 2.09E-05 16/26 K.VQALEEANNDLENK.L sp|P35527|K1C9_HUMAN 1 1585.7584 -1 65122 13181 2 1585.7577 793.8865 "Keratin, type I cytoskeletal 9 OS=Homo sapiens OX=9606 GN=KRT9 PE=1 SV=3" 4 2483.8 - 764294 - - - -0.4288 - 3.143 0.607 - 856.5 1 2 0 -0.0007 14 0 0 0 0.00E+00 0.00E+00 - - - 6.3979 0.9999 221125_WJC_METTL3_EV_vs_WT_F05.13182.13182.2 0.002 13/18 R.KESYSIYVYK.V "sp|Q8N257|H2B3B_HUMAN,sp|P33778|H2B1B_HUMAN,sp|Q6DN03|H2B2C_HUMAN,sp|P23527|H2B1O_HUMAN,sp|Q6DRA6|H2B2D_HUMAN,sp|Q16778|H2B2E_HUMAN,sp|P06899|H2B1J_HUMAN" 7 1278.6496 1.34 65123 13182 2 1278.648756 640.3321 Histone H2B type 3-B OS=Homo sapiens OX=9606 GN=H2BU1 PE=1 SV=3 8.38 2483.9 - 646288 - - - -0.6632 - 2.606 0.491 - 535 1 2 0 -0.0008 10 0 0 0 2.10E+07 1.57E+07 - - - 5.3408 0.9999 221125_WJC_METTL3_EV_vs_WT_F05.13183.13183.3 0.000181 16/52 R.IQHAVQLATEPLEK[136.11].A "sp|P49589|SYCC_HUMAN,tr|B4DKY1|B4DKY1_HUMAN" 2 1583.8763 0.49 65124 13183 3 1583.876896 528.966 "Cysteine--tRNA ligase, cytoplasmic OS=Homo sapiens OX=9606 GN=CARS1 PE=1 SV=3" 5.4 2484 - 638617 - - - 0.4034 - 2.309 0.378 - 365.7 1 2 0 0.0006 14 0 0 0 2.35E+06 4.80E+06 - - - 4.978 1 221125_WJC_METTL3_EV_vs_WT_F05.13184.13184.2 1.43E-07 13/22 K.DNNQFASASLDR.T "sp|P35606|COPB2_HUMAN,tr|H0Y938|H0Y938_HUMAN,tr|A0A7I2V3G0|A0A7I2V3G0_HUMAN,tr|A0A7I2V258|A0A7I2V258_HUMAN,tr|D6R997|D6R997_HUMAN,tr|H0YAC7|H0YAC7_HUMAN,tr|A0A7I2YQF9|A0A7I2YQF9_HUMAN" 7 1336.6008 1.07 65125 13184 2 1336.599096 669.3077 Coatomer subunit beta' OS=Homo sapiens OX=9606 GN=COPB2 PE=1 SV=2 4.21 2484.2 - 582815 - - - -1.2427 - 2.769 0.607 - 688.5 1 2 0 -0.0017 12 0 0 0 5.93E+06 5.53E+06 - - - 6.2036 0.9999 221125_WJC_METTL3_EV_vs_WT_F05.13186.13186.2 1.87E-05 15/18 K.K[136.11]SDVETIFSK[136.11].Y "sp|Q9UKM9|RALY_HUMAN,tr|Q5QPM2|Q5QPM2_HUMAN,tr|Q5QPM1|Q5QPM1_HUMAN,tr|Q5QPL9|Q5QPL9_HUMAN" 4 1168.6311 0.88 65127 13186 2 1168.631085 585.3228 RNA-binding protein Raly OS=Homo sapiens OX=9606 GN=RALY PE=1 SV=1 6.07 2484.4 - 415238 - - - 0.0265 - 2.898 0.445 - 647.2 1 2 0 0 10 0 0 0 2.09E+06 2.38E+06 - - - 5.2978 0.8268 221125_WJC_METTL3_EV_vs_WT_F05.13187.13187.3 0.851 Oct-36 K.LSPWIR[166.11]PDSK[136.11].V "sp|O14744|ANM5_HUMAN,tr|C9JSX3|C9JSX3_HUMAN,tr|G3V580|G3V580_HUMAN,tr|G3V2L6|G3V2L6_HUMAN,tr|G3V2X6|G3V2X6_HUMAN,tr|G3V5L5|G3V5L5_HUMAN" 6 1215.6731 2.52 65128 13187 3 1215.672287 406.2316 Protein arginine N-methyltransferase 5 OS=Homo sapiens OX=9606 GN=PRMT5 PE=1 SV=4 8.75 2484.5 - 403243 - - - -0.6498 - 1.709 0 - 110 1 2 0 -0.0008 10 0 0 0 2.29E+07 9.09E+06 - - - 0.1049 1 221125_WJC_METTL3_EV_vs_WT_F05.13188.13188.2 2.35E-07 20-Dec R.SGDQNWVSVSR.A "sp|Q9H0E9|BRD8_HUMAN,tr|B5MCW3|B5MCW3_HUMAN,tr|H7C179|H7C179_HUMAN,tr|H7C128|H7C128_HUMAN,tr|H7C127|H7C127_HUMAN,tr|F8WBH2|F8WBH2_HUMAN" 6 1233.5738 1.93 65129 13188 2 1233.571369 617.7942 Bromodomain-containing protein 8 OS=Homo sapiens OX=9606 GN=BRD8 PE=1 SV=2 5.55 2484.7 - 401231 - - - -1.982 - 2.578 0.623 - 628.4 1 2 0 -0.0024 11 0 0 0 4.82E+06 2.51E+06 - - - 6.2036 1 221125_WJC_METTL3_EV_vs_WT_F05.13192.13192.2 7.75E-08 26-Dec R.MQALEPYPANESSK.L "sp|O43148|MCES_HUMAN,tr|K7EP06|K7EP06_HUMAN" 2 1563.7239 1.43 65132 13192 2 1563.724439 782.8692 mRNA cap guanine-N7 methyltransferase OS=Homo sapiens OX=9606 GN=RNMT PE=1 SV=1 4.53 2485.1 - 498743 - - - 0.3396 - 2.614 0.592 - 458.3 1 2 0 0.0005 14 0 0 0 2.52E+07 1.76E+07 - - - 5.8246 1 221125_WJC_METTL3_EV_vs_WT_F05.13193.13193.2 7.91E-07 14/26 R.TSQENSPALLGVQK.G "sp|Q8IWZ3|ANKH1_HUMAN,tr|E9PDP5|E9PDP5_HUMAN,tr|H3BLS9|H3BLS9_HUMAN,tr|H7C2F5|H7C2F5_HUMAN" 4 1470.7678 1.83 65133 13193 2 1470.768929 736.3912 Ankyrin repeat and KH domain-containing protein 1 OS=Homo sapiens OX=9606 GN=ANKHD1 PE=1 SV=1 5.66 2485.3 - 1.14E+06 - - - 0.7527 - 3.042 0.538 - 733 1 2 0 0.0011 14 0 0 0 4.00E+07 2.19E+07 - - - 5.8061 1 221125_WJC_METTL3_EV_vs_WT_F05.13194.13194.3 1.20E-07 13/52 K.VQALEEANNDLENK.L sp|P35527|K1C9_HUMAN 1 1585.7584 25223.9 65134 13194 3 1585.76006 529.5934 "Keratin, type I cytoskeletal 9 OS=Homo sapiens OX=9606 GN=KRT9 PE=1 SV=3" 4 2485.3 - 6.66E+06 - - - 1.0594 - 2.847 0.603 - 332.6 1 2 0 0.0017 14 0 0 0 4.52E+09 1.79E+05 - - - 8.0429 0.9999 221125_WJC_METTL3_EV_vs_WT_F05.13197.13197.2 2.97E-05 15/26 K.GYDVIAQAQSGTGK.T "sp|Q14240|IF4A2_HUMAN,sp|P60842|IF4A1_HUMAN,tr|J3KTB5|J3KTB5_HUMAN,tr|J3KT04|J3KT04_HUMAN,tr|J3KS93|J3KS93_HUMAN,tr|E7EMV8|E7EMV8_HUMAN,tr|J3KT12|J3KT12_HUMAN,tr|J3QKZ9|J3QKZ9_HUMAN,tr|J3QS69|J3QS69_HUMAN,tr|J3QL43|J3QL43_HUMAN,tr|E7EQG2|E7EQG2_HUMAN,tr|J3KS25|J3KS25_HUMAN,tr|J3QLN6|J3QLN6_HUMAN,tr|J3QR64|J3QR64_HUMAN,tr|J3KSN7|J3KSN7_HUMAN" 15 1393.6838 1.21 65137 13197 2 1393.68371 697.8492 Eukaryotic initiation factor 4A-II OS=Homo sapiens OX=9606 GN=EIF4A2 PE=1 SV=2 5.83 2485.5 - 1.12E+06 - - - -0.0344 - 2.769 0.547 - 670.3 1 2 0 0 14 0 0 0 3.47E+07 2.86E+07 - - - 5.637 1 221125_WJC_METTL3_EV_vs_WT_F05.13198.13198.2 1.85E-07 14/26 R.TSQENSPALLGVQK[136.11].G "sp|Q8IWZ3|ANKH1_HUMAN,tr|E9PDP5|E9PDP5_HUMAN,tr|H3BLS9|H3BLS9_HUMAN,tr|H7C2F5|H7C2F5_HUMAN" 4 1478.782 1.83 65138 13198 2 1478.781678 740.3983 Ankyrin repeat and KH domain-containing protein 1 OS=Homo sapiens OX=9606 GN=ANKHD1 PE=1 SV=1 5.66 2485.6 - 911632 - - - -0.2326 - 3.193 0.54 - 741.5 1 2 0 -0.0003 14 0 0 0 4.00E+07 2.19E+07 - - - 5.9427 1 221125_WJC_METTL3_EV_vs_WT_F05.13199.13199.2 2.86E-08 22-Dec K.DNNQFASASLDR[166.11].T "sp|P35606|COPB2_HUMAN,tr|H0Y938|H0Y938_HUMAN,tr|A0A7I2V3G0|A0A7I2V3G0_HUMAN,tr|A0A7I2V258|A0A7I2V258_HUMAN,tr|D6R997|D6R997_HUMAN,tr|H0YAC7|H0YAC7_HUMAN,tr|A0A7I2YQF9|A0A7I2YQF9_HUMAN" 7 1346.609 1.07 65139 13199 2 1346.605594 674.3118 Coatomer subunit beta' OS=Homo sapiens OX=9606 GN=COPB2 PE=1 SV=2 4.21 2485.7 - 865131 - - - -2.5494 - 2.701 0.634 - 582.8 1 2 0 -0.0034 12 0 0 0 5.93E+06 5.53E+06 - - - 6.337 0.9999 221125_WJC_METTL3_EV_vs_WT_F05.13200.13200.3 3.17E-05 13/52 K.VPTTEK[136.11]PTVTVNFR[166.11].K "sp|Q04637|IF4G1_HUMAN,tr|E7EUU4|E7EUU4_HUMAN,tr|E9PGM1|E9PGM1_HUMAN,tr|C9J6B6|C9J6B6_HUMAN,tr|E7EX73|E7EX73_HUMAN,tr|C9K073|C9K073_HUMAN,tr|A0A7I2Y1C3|A0A7I2Y1C3_HUMAN,tr|C9JF13|C9JF13_HUMAN" 8 1605.8845 0.29 65140 13200 3 1605.885056 536.3021 Eukaryotic translation initiation factor 4 gamma 1 OS=Homo sapiens OX=9606 GN=EIF4G1 PE=1 SV=4 8.72 2485.8 - 852308 - - - 0.3294 - 2.012 0.398 - 206.7 1 2 0 0.0005 14 0 0 0 2.82E+06 9.81E+06 - - - 4.8351 0.9997 221125_WJC_METTL3_EV_vs_WT_F05.13203.13203.2 1.06E-06 13/24 K.QNQGAAPEIQALK.N "sp|Q86VS8|HOOK3_HUMAN,tr|H0YDM4|H0YDM4_HUMAN" 2 1366.7205 10.25 65143 13203 2 1366.723881 684.3675 Protein Hook homolog 3 OS=Homo sapiens OX=9606 GN=HOOK3 PE=1 SV=2 6 2486.2 - 485429 - - - 2.4899 - 2.451 0.522 - 625.5 1 2 0 0.0034 13 0 0 0 1.54E+07 1.50E+06 - - - 5.1963 0.9999 221125_WJC_METTL3_EV_vs_WT_F05.13207.13207.2 7.73E-05 13/26 R.MQALEPYPANESSK[136.11].L "sp|O43148|MCES_HUMAN,tr|K7EP06|K7EP06_HUMAN" 2 1571.7381 1.47 65147 13207 2 1571.740194 786.8763 mRNA cap guanine-N7 methyltransferase OS=Homo sapiens OX=9606 GN=RNMT PE=1 SV=1 4.53 2486.7 - 307967 - - - 1.3272 - 2.797 0.55 - 523.6 1 2 0 0.0021 14 0 0 0 2.70E+07 1.83E+07 - - - 5.6837 0.9956 221125_WJC_METTL3_EV_vs_WT_F05.13210.13210.3 0.0314 Sep-36 K.NGDHFSYFSR[166.11].S "sp|P49916|DNLI3_HUMAN,tr|K7ERZ5|K7ERZ5_HUMAN" 2 1238.5344 0.89 65150 13210 3 1238.531343 413.8521 DNA ligase 3 OS=Homo sapiens OX=9606 GN=LIG3 PE=1 SV=2 6.74 2487.1 - 246448 - - - -2.4723 - 1.384 0.308 - 104.1 1 2 0 -0.0031 10 0 0 0 1.43E+06 1.61E+06 - - - 2.9221 0.9997 221125_WJC_METTL3_EV_vs_WT_F05.13214.13214.3 0.00419 14/48 R.MLWMDKEKEESMK.E "sp|P0CG22|DR4L1_HUMAN,sp|Q9BTZ2|DHRS4_HUMAN,tr|H0YNP7|H0YNP7_HUMAN,tr|A0A087WXI8|A0A087WXI8_HUMAN" 4 1683.767 0.09 65153 13214 3 1683.771319 562.263 Putative dehydrogenase\reductase SDR family member 4-like 1 OS=Homo sapiens OX=9606 GN=DHRS4L1 PE=5 SV=1 4.87 2487.7 - 389672 - - - 2.5437 - 2.733 0.491 - 222.4 1 2 2 0.0043 13 0 0 0 6.10E+06 6.92E+07 - - - 6.7389 1 221125_WJC_METTL3_EV_vs_WT_F05.13215.13215.2 2.38E-08 15/26 K.GYDVIAQAQSGTGK[136.11].T "sp|Q14240|IF4A2_HUMAN,sp|P60842|IF4A1_HUMAN,tr|J3KTB5|J3KTB5_HUMAN,tr|J3KT04|J3KT04_HUMAN,tr|J3KS93|J3KS93_HUMAN,tr|E7EMV8|E7EMV8_HUMAN,tr|J3KT12|J3KT12_HUMAN,tr|J3QKZ9|J3QKZ9_HUMAN,tr|J3QS69|J3QS69_HUMAN,tr|J3QL43|J3QL43_HUMAN,tr|E7EQG2|E7EQG2_HUMAN,tr|J3KS25|J3KS25_HUMAN,tr|J3QLN6|J3QLN6_HUMAN,tr|J3QR64|J3QR64_HUMAN,tr|J3KSN7|J3KSN7_HUMAN" 15 1401.698 1.21 65154 13215 2 1401.698896 701.8563 Eukaryotic initiation factor 4A-II OS=Homo sapiens OX=9606 GN=EIF4A2 PE=1 SV=2 5.83 2487.8 - 2.13E+06 - - - 0.6692 - 2.932 0.589 - 628.1 1 2 0 0.0009 14 0 0 0 3.47E+07 2.86E+07 - - - 6.0904 0.9998 221125_WJC_METTL3_EV_vs_WT_F05.13217.13217.3 0.000106 13/52 R.QEEELQAK[136.11]DEELLK[136.11].V sp|P35580|MYH10_HUMAN 1 1716.8753 0.98 65156 13217 3 1716.87407 573.299 Myosin-10 OS=Homo sapiens OX=9606 GN=MYH10 PE=1 SV=3 4.14 2488 - 871530 - - - -0.6931 - 2.443 0.46 - 228.8 1 2 1 -0.0012 14 0 0 0 3.60E+07 3.69E+07 - - - 6.042 0.9999 221125_WJC_METTL3_EV_vs_WT_F05.13219.13219.3 0.000271 Dec-36 K.K[136.11]SDVETIFSK[136.11].Y "sp|Q9UKM9|RALY_HUMAN,tr|Q5QPM2|Q5QPM2_HUMAN,tr|Q5QPM1|Q5QPM1_HUMAN,tr|Q5QPL9|Q5QPL9_HUMAN" 4 1168.6311 1.38 65158 13219 3 1168.630436 390.551 RNA-binding protein Raly OS=Homo sapiens OX=9606 GN=RALY PE=1 SV=1 6.07 2488.2 - 529636 - - - -0.5288 - 2.372 0.418 - 260.2 1 2 0 -0.0006 10 0 0 0 5.68E+06 4.12E+06 - - - 5.7226 0.9992 221125_WJC_METTL3_EV_vs_WT_F05.13222.13222.3 0.0153 Aug-40 R.NGHVGISFVPK[136.11].E "sp|P21333|FLNA_HUMAN,tr|Q60FE5|Q60FE5_HUMAN" 2 1161.6386 0.14 65161 13222 3 1161.637431 388.2201 Filamin-A OS=Homo sapiens OX=9606 GN=FLNA PE=1 SV=4 8.76 2488.6 - 432462 - - - -1.0003 - 1.539 0.334 - 79 1 2 0 -0.0012 11 0 0 0 2.68E+05 1.93E+06 - - - 3.4882 0.919 221125_WJC_METTL3_EV_vs_WT_F05.13227.13227.2 0.202 22-Jul K.LPDLK[136.11]DAEAVQK[136.11].F sp|Q15388|TOM20_HUMAN 1 1341.7475 2.4 65166 13227 2 1341.749949 671.881 Mitochondrial import receptor subunit TOM20 homolog OS=Homo sapiens OX=9606 GN=TOMM20 PE=1 SV=1 4.56 2489.3 - 178344 - - - 1.8394 - 1.328 0.225 - 98.8 2 2 1 0.0025 12 0 0 0 4.61E+06 1.92E+06 - - - 1.314 0.9999 221125_WJC_METTL3_EV_vs_WT_F05.13228.13228.2 1.50E-06 13/28 R.DGSLANNPYPGDVTK.F sp|Q5T6F2|UBAP2_HUMAN 1 1546.7264 1.09 65167 13228 2 1546.726469 774.3705 Ubiquitin-associated protein 2 OS=Homo sapiens OX=9606 GN=UBAP2 PE=1 SV=1 4.21 2489.4 - 175182 - - - 0.0763 - 2.618 0.44 - 424.3 1 2 0 0.0001 15 0 0 0 1.66E+07 1.52E+07 - - - 4.6569 0.999 221125_WJC_METTL3_EV_vs_WT_F05.13230.13230.3 0.00646 Dec-48 R.GIHVEVPPAEAER.L sp|P38117|ETFB_HUMAN 1 1402.7205 1.42 65169 13230 3 1402.722191 468.5808 Electron transfer flavoprotein subunit beta OS=Homo sapiens OX=9606 GN=ETFB PE=1 SV=3 4.75 2489.6 - 188406 - - - 1.2212 - 1.786 0.299 - 143.9 1 2 0 0.0017 13 0 0 0 1.87E+06 1.31E+06 - - - 3.4456 0.9999 221125_WJC_METTL3_EV_vs_WT_F05.13236.13236.3 2.33E-07 16/52 R.QEEELQAKDEELLK.V sp|P35580|MYH10_HUMAN 1 1700.8469 0.98 65173 13236 3 1700.844597 567.9562 Myosin-10 OS=Homo sapiens OX=9606 GN=MYH10 PE=1 SV=3 4.14 2490.2 - 2.13E+06 - - - -1.3305 - 2.675 0.515 - 437.3 1 2 1 -0.0023 14 0 0 0 3.60E+07 3.69E+07 - - - 6.896 0.9928 221125_WJC_METTL3_EV_vs_WT_F05.13237.13237.3 0.0632 Sep-36 R.FKVEESYDLK.D sp|P29508|SPB3_HUMAN 1 1256.6289 452 65174 13237 3 1256.626341 419.8836 Serpin B3 OS=Homo sapiens OX=9606 GN=SERPINB3 PE=1 SV=2 4.68 2490.3 - 1.95E+06 - - - -2.0117 - 1.704 0.298 - 116.6 1 2 1 -0.0025 10 0 0 0 4.11E+07 9.09E+04 - - - 3.4182 0.9997 221125_WJC_METTL3_EV_vs_WT_F05.13238.13238.3 1.48E-05 14/48 R.SLPLVQVDEKGEK.V sp|Q92615|LAR4B_HUMAN 1 1440.7824 1.23 65175 13238 3 1440.778553 481.2681 La-related protein 4B OS=Homo sapiens OX=9606 GN=LARP4B PE=1 SV=3 4.68 2490.3 - 1.36E+06 - - - -2.677 - 2.678 0.51 - 185.5 1 2 1 -0.0039 13 0 0 0 2.13E+08 1.73E+08 - - - 6.8957 0.9999 221125_WJC_METTL3_EV_vs_WT_F05.13239.13239.3 3.12E-05 14/48 R.SLPLVQVDEK[136.11]GEK[136.11].V sp|Q92615|LAR4B_HUMAN 1 1456.8108 1.23 65176 13239 3 1456.807846 486.6109 La-related protein 4B OS=Homo sapiens OX=9606 GN=LARP4B PE=1 SV=3 4.68 2490.4 - 1.25E+06 - - - -2.0346 - 2.896 0.531 - 161.7 1 2 1 -0.003 13 0 0 0 2.13E+08 1.73E+08 - - - 7.3423 0.9998 221125_WJC_METTL3_EV_vs_WT_F05.13240.13240.2 1.52E-05 30-Dec R.TPSGSHSGPVPSQGLV.- sp|Q9Y6V7|DDX49_HUMAN 1 1505.7474 - 65177 13240 2 1505.74862 753.881 Probable ATP-dependent RNA helicase DDX49 OS=Homo sapiens OX=9606 GN=DDX49 PE=1 SV=1 6.4 2490.5 - 817953 - - - 0.7963 - 2.009 0.463 - 251.2 1 2 0 0.0012 16 0 0 0 - - - - - 4.1755 0.9991 221125_WJC_METTL3_EV_vs_WT_F05.13241.13241.4 0.000208 14/72 R.MLWMDKEKEESMK.E "sp|P0CG22|DR4L1_HUMAN,sp|Q9BTZ2|DHRS4_HUMAN,tr|H0YNP7|H0YNP7_HUMAN,tr|A0A087WXI8|A0A087WXI8_HUMAN" 4 1683.767 2.1 65178 13241 4 1683.764231 421.949 Putative dehydrogenase\reductase SDR family member 4-like 1 OS=Homo sapiens OX=9606 GN=DHRS4L1 PE=5 SV=1 4.87 2490.7 - 611265 - - - -1.6659 - 2.909 0.371 - 172.3 1 2 2 -0.0028 13 0 0 0 8.10E+06 3.86E+06 - - - 2.8503 0.9752 221125_WJC_METTL3_EV_vs_WT_F05.13243.13243.3 0.00019 Nov-48 K.FLGGDMEHTHLVK[136.11].G "sp|Q13123|RED_HUMAN,tr|D6REL4|D6REL4_HUMAN,tr|E7EQZ7|E7EQZ7_HUMAN" 3 1490.7431 4.13 65180 13243 3 1490.745549 497.9217 Protein Red OS=Homo sapiens OX=9606 GN=IK PE=1 SV=3 5.99 2490.9 - 509819 - - - 1.62 - 1.933 0.119 - 61.2 2 2 0 0.0024 13 0 0 0 2.27E+07 5.48E+06 - - - 1.5137 0.9998 221125_WJC_METTL3_EV_vs_WT_F05.13250.13250.3 5.31E-05 15/48 K.K[136.11]QEQLTPGVVYVR[166.11].H sp|Q9BYG3|MK67I_HUMAN 1 1533.8634 1.26 65185 13250 3 1533.8632 512.2951 MKI67 FHA domain-interacting nucleolar phosphoprotein OS=Homo sapiens OX=9606 GN=NIFK PE=1 SV=1 8.59 2491.7 - 856950 - - - -0.1291 - 2.267 0.326 - 349.7 1 2 0 -0.0002 13 0 0 0 2.87E+07 2.28E+07 - - - 4.3936 0.9998 221125_WJC_METTL3_EV_vs_WT_F05.13251.13251.3 1.09E-05 13/48 K.SFSQSSNLITHVR.T sp|Q9UEG4|ZN629_HUMAN 1 1474.7528 0.92 65186 13251 3 1474.749168 492.5916 Zinc finger protein 629 OS=Homo sapiens OX=9606 GN=ZNF629 PE=1 SV=2 9.49 2491.8 - 617546 - - - -2.4906 - 2.027 0.469 - 167.4 1 2 0 -0.0037 13 0 0 0 1.02E+07 1.12E+07 - - - 5.6835 0.9999 221125_WJC_METTL3_EV_vs_WT_F05.13252.13252.3 0.000944 Nov-44 K.TAQNHPMLVELK[136.11].N "sp|Q9Y4Z0|LSM4_HUMAN,tr|M0QXB0|M0QXB0_HUMAN,tr|V9GZ56|V9GZ56_HUMAN" 3 1387.7373 1.93 65187 13252 3 1387.735131 463.5864 U6 snRNA-associated Sm-like protein LSm4 OS=Homo sapiens OX=9606 GN=LSM4 PE=1 SV=1 6.41 2491.9 - 605720 - - - -1.5781 - 2.298 0.416 - 165.5 1 2 0 -0.0022 12 0 0 0 7.95E+07 4.12E+07 - - - 5.4837 0.963 221125_WJC_METTL3_EV_vs_WT_F05.13254.13254.3 0.0172 Sep-48 K.TTSPLEEEEREIK.S "sp|Q9UKV3|ACINU_HUMAN,tr|S4R3H4|S4R3H4_HUMAN,tr|E7EQT4|E7EQT4_HUMAN" 3 1559.7679 2.34 65189 13254 3 1559.773067 520.9299 Apoptotic chromatin condensation inducer in the nucleus OS=Homo sapiens OX=9606 GN=ACIN1 PE=1 SV=2 4.32 2492.2 - 470964 - - - 3.3242 - 1.833 0.247 - 100 1 2 1 0.0052 13 0 0 0 7.87E+06 3.37E+06 - - - 2.9353 0.9891 221125_WJC_METTL3_EV_vs_WT_F05.13259.13259.2 0.000362 22-Oct R.RAEQDSTTVAAF.A "sp|Q86U44|MTA70_HUMAN,tr|F5H6D8|F5H6D8_HUMAN,tr|H0YFV6|H0YFV6_HUMAN,tr|B4DTN4|B4DTN4_HUMAN" 4 1294.6153 0.02 65192 13259 2 1294.614759 648.3149 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 4.37 2492.8 - 3.66E+06 - - - -0.4519 - 2.097 0.439 - 343.9 1 1 0 -0.0006 12 0 0 0 1.66E+08 7.71E+09 - - - 4.2317 0.9775 221125_WJC_METTL3_EV_vs_WT_F05.13261.13261.2 0.0344 18-Dec R.FKVEESYDLK.D sp|P29508|SPB3_HUMAN 1 1256.6289 0.89 65194 13261 2 1256.633161 629.3217 Serpin B3 OS=Homo sapiens OX=9606 GN=SERPINB3 PE=1 SV=2 4.68 2493 - 647465 - - - 3.4155 - 1.948 0.347 - 382.3 1 2 1 0.0043 10 0 0 0 1.05E+07 1.18E+07 - - - 3.4638 1 221125_WJC_METTL3_EV_vs_WT_F05.13262.13262.2 1.27E-06 14/18 R.HGELWC[160.03]AVSK.D sp|O94906|PRP6_HUMAN 1 1185.5601 2.58 65195 13262 2 1185.559163 593.7873 Pre-mRNA-processing factor 6 OS=Homo sapiens OX=9606 GN=PRPF6 PE=1 SV=1 6.74 2493.2 - 562604 - - - -0.7718 - 2.662 0.579 - 574.3 1 2 0 -0.0009 10 0 0 0 1.84E+07 7.15E+06 - - - 6.0501 1 221125_WJC_METTL3_EV_vs_WT_F05.13263.13263.2 0.000117 13/28 R.DGSLANNPYPGDVTK[136.11].F sp|Q5T6F2|UBAP2_HUMAN 1 1554.7406 1.08 65196 13263 2 1554.741616 778.3776 Ubiquitin-associated protein 2 OS=Homo sapiens OX=9606 GN=UBAP2 PE=1 SV=1 4.21 2493.3 - 509146 - - - 0.685 - 2.679 0.582 - 408.4 1 2 0 0.0011 15 0 0 0 1.64E+07 1.52E+07 - - - 5.7621 0.959 221125_WJC_METTL3_EV_vs_WT_F05.13270.13270.3 0.0026 Oct-36 N.KTLLDIDNTR.M sp|P35527|K1C9_HUMAN 1 1187.651 8.59 65201 13270 3 1187.648557 396.8909 "Keratin, type I cytoskeletal 9 OS=Homo sapiens OX=9606 GN=KRT9 PE=1 SV=3" 5.96 2494.2 - 790149 - - - -2.0578 - 1.932 0.362 - 135.4 1 1 0 -0.0024 10 0 0 0 1.47E+07 1.71E+06 - - - 4.4985 0.9994 221125_WJC_METTL3_EV_vs_WT_F05.13273.13273.3 0.000607 14/40 K.VGYELKDEIER.K sp|Q8WWY3|PRP31_HUMAN 1 1349.6827 2.56 65202 13273 3 1349.68001 450.9015 U4\U6 small nuclear ribonucleoprotein Prp31 OS=Homo sapiens OX=9606 GN=PRPF31 PE=1 SV=2 4.41 2494.6 - 1.68E+06 - - - -1.9901 - 2.519 0.386 - 309.2 1 2 1 -0.0027 11 0 0 0 3.63E+07 1.42E+07 - - - 5.4673 0.9996 221125_WJC_METTL3_EV_vs_WT_F05.13275.13275.3 7.68E-06 13/40 K.VGYELK[136.11]DEIER[166.11].K sp|Q8WWY3|PRP31_HUMAN 1 1367.7052 2.54 65204 13275 3 1367.70139 456.909 U4\U6 small nuclear ribonucleoprotein Prp31 OS=Homo sapiens OX=9606 GN=PRPF31 PE=1 SV=2 4.41 2494.8 - 925577 - - - -2.7608 - 2.388 0.513 - 246.1 1 2 1 -0.0038 11 0 0 0 3.63E+07 1.43E+07 - - - 6.7312 1 221125_WJC_METTL3_EV_vs_WT_F05.13282.13282.2 4.72E-06 15/20 L.PLVQVDEKGEK.V sp|Q92615|LAR4B_HUMAN 1 1240.6663 1.15 65209 13282 2 1240.666515 621.3404 La-related protein 4B OS=Homo sapiens OX=9606 GN=LARP4B PE=1 SV=3 4.68 2495.7 - 588816 - - - 0.1596 - 2.837 0.601 - 803.6 1 1 1 0.0002 11 0 0 0 1.84E+07 1.60E+07 - - - 6.3008 0.9673 221125_WJC_METTL3_EV_vs_WT_F05.13284.13284.2 1.20E-05 26-Nov R.R[166.11]AEQDSTTVAAFAS.S "sp|Q86U44|MTA70_HUMAN,tr|F5H6D8|F5H6D8_HUMAN,tr|H0YFV6|H0YFV6_HUMAN,tr|B4DTN4|B4DTN4_HUMAN" 4 1462.6928 0.01 65210 13284 2 1462.688716 732.3537 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 4.37 2495.9 - 8.66E+06 - - - -2.762 - 1.834 0.533 - 226.1 1 1 0 -0.004 14 0 0 0 1.25E+07 1.26E+09 - - - 4.4984 0.9883 221125_WJC_METTL3_EV_vs_WT_F05.13286.13286.2 7.17E-08 28-Dec S.SLVSGLNSSASEPAK[136.11].E "sp|Q86U44|MTA70_HUMAN,tr|F5H6D8|F5H6D8_HUMAN,tr|H0YFV6|H0YFV6_HUMAN,tr|B4DTN4|B4DTN4_HUMAN" 4 1453.7504 0 65211 13286 2 1453.74727 727.8825 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 5.72 2496.1 - 8.12E+06 - - - -2.1448 - 2.618 0.582 - 350 1 1 0 -0.0031 15 0 0 0 1.28E+06 2.64E+08 - - - 5.7048 0.9998 221125_WJC_METTL3_EV_vs_WT_F05.13293.13293.2 8.97E-06 18-Dec R.SGFSSISVSR.S "sp|P48668|K2C6C_HUMAN,sp|P04259|K2C6B_HUMAN" 2 1025.5142 165.5 65216 13293 2 1025.515052 513.7644 "Keratin, type II cytoskeletal 6C OS=Homo sapiens OX=9606 GN=KRT6C PE=1 SV=3" 9.47 2496.9 - 1.25E+06 - - - 0.8562 - 2.148 0.42 - 366.3 1 2 0 0.0009 10 0 0 0 3.71E+07 2.24E+05 - - - 4.2769 0.9946 221125_WJC_METTL3_EV_vs_WT_F05.13298.13298.3 0.0664 Sep-52 K.LLVPAAEGEDSLK[136.11]K[136.11].M "sp|Q96PU8|QKI_HUMAN,tr|F5GYM3|F5GYM3_HUMAN,tr|F5GXS8|F5GXS8_HUMAN,tr|H0YG47|H0YG47_HUMAN,tr|H0YGD6|H0YGD6_HUMAN" 5 1484.8421 2.19 65221 13298 3 1484.83651 495.9546 Protein quaking OS=Homo sapiens OX=9606 GN=QKI PE=1 SV=1 4.68 2497.4 - 555773 - - - -3.7714 - 1.846 0.324 - 51.7 5 2 0 -0.0056 14 0 0 0 1.75E+07 7.98E+06 - - - 3.4564 0.9633 221125_WJC_METTL3_EV_vs_WT_F05.13299.13299.3 3.44E-08 Dec-40 L.PLVQVDEKGEK.V sp|Q92615|LAR4B_HUMAN 1 1240.6663 3.44 65222 13299 3 1240.662691 414.5627 La-related protein 4B OS=Homo sapiens OX=9606 GN=LARP4B PE=1 SV=3 4.68 2497.6 - 529139 - - - -2.9226 - 2.747 0.493 - 203.9 1 1 1 -0.0036 11 0 0 0 7.45E+06 2.16E+06 - - - 6.9061 0.998 221125_WJC_METTL3_EV_vs_WT_F05.13303.13303.2 0.00882 14-Sep R.TDFTPHWK.Q "sp|Q8WXI9|P66B_HUMAN,tr|A0A0U1RRM1|A0A0U1RRM1_HUMAN,tr|A0A0U1RR30|A0A0U1RR30_HUMAN" 3 1030.4872 1.14 65224 13303 2 1030.491199 516.2509 Transcriptional repressor p66-beta OS=Homo sapiens OX=9606 GN=GATAD2B PE=1 SV=1 6.41 2498.1 - 678113 - - - 3.8506 - 1.969 0.375 - 318.7 1 2 0 0.004 8 0 0 0 1.85E+07 1.62E+07 - - - 3.8529 0.9999 221125_WJC_METTL3_EV_vs_WT_F05.13304.13304.3 0.000227 17/52 K.LLVPAAEGEDSLKK.M "sp|Q96PU8|QKI_HUMAN,tr|F5GYM3|F5GYM3_HUMAN,tr|F5GXS8|F5GXS8_HUMAN,tr|H0YG47|H0YG47_HUMAN,tr|H0YGD6|H0YGD6_HUMAN" 5 1468.8137 2.19 65225 13304 3 1468.811939 490.6118 Protein quaking OS=Homo sapiens OX=9606 GN=QKI PE=1 SV=1 4.68 2498.2 - 1.19E+06 - - - -1.2057 - 2.336 0.388 - 310.3 1 2 0 -0.0018 14 0 0 0 1.75E+07 7.98E+06 - - - 5.1201 0.9922 221125_WJC_METTL3_EV_vs_WT_F05.13311.13311.2 1.04E-05 22-Sep R.R[166.11]AEQDSTTVAAF.A "sp|Q86U44|MTA70_HUMAN,tr|F5H6D8|F5H6D8_HUMAN,tr|H0YFV6|H0YFV6_HUMAN,tr|B4DTN4|B4DTN4_HUMAN" 4 1304.6236 0.02 65230 13311 2 1304.621995 653.3191 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 4.37 2499.1 - 2.19E+08 - - - -1.241 - 2.018 0.596 - 249.4 1 1 0 -0.0016 12 0 0 0 1.66E+08 7.71E+09 - - - 5.2899 1 221125_WJC_METTL3_EV_vs_WT_F05.13312.13312.2 5.29E-08 15/24 R.SLPLVQVDEKGEK.V sp|Q92615|LAR4B_HUMAN 1 1440.7824 1.64 65231 13312 2 1440.780769 721.3985 La-related protein 4B OS=Homo sapiens OX=9606 GN=LARP4B PE=1 SV=3 4.68 2499.2 - 1.34E+06 - - - -1.139 - 2.627 0.597 - 705.5 1 2 1 -0.0016 13 0 0 0 2.32E+07 1.42E+07 - - - 5.9288 1 221125_WJC_METTL3_EV_vs_WT_F05.13315.13315.3 3.51E-08 16/48 R.KILQDGGLQVVEK.Q "sp|O43175|SERA_HUMAN,tr|A0A2C9F2M7|A0A2C9F2M7_HUMAN,tr|A0A286YFB2|A0A286YFB2_HUMAN,tr|A0A286YF34|A0A286YF34_HUMAN,tr|A0A286YFC8|A0A286YFC8_HUMAN,tr|A0A286YF22|A0A286YF22_HUMAN,tr|A0A286YFL2|A0A286YFL2_HUMAN,tr|A0A286YFA2|A0A286YFA2_HUMAN,tr|A0A286YFM8|A0A286YFM8_HUMAN,tr|A0A286YER3|A0A286YER3_HUMAN,tr|A0A286YFF3|A0A286YFF3_HUMAN,tr|A0A286YFK5|A0A286YFK5_HUMAN" 12 1425.8191 1.18 65234 13315 3 1425.817051 476.2803 D-3-phosphoglycerate dehydrogenase OS=Homo sapiens OX=9606 GN=PHGDH PE=1 SV=4 6.07 2499.6 - 698948 - - - -1.4574 - 2.778 0.509 - 439.6 1 2 0 -0.0021 13 0 0 0 2.87E+07 2.43E+07 - - - 6.9845 0.9665 221125_WJC_METTL3_EV_vs_WT_F05.13316.13316.3 0.513 Oct-44 R.QWLNSGHINDVR[166.11].H "sp|O14974|MYPT1_HUMAN,tr|H0YHL8|H0YHL8_HUMAN,tr|F8VZN8|F8VZN8_HUMAN,tr|F8VW28|F8VW28_HUMAN" 4 1447.7196 0.83 65235 13316 3 1447.717451 483.5805 Protein phosphatase 1 regulatory subunit 12A OS=Homo sapiens OX=9606 GN=PPP1R12A PE=1 SV=1 6.74 2499.7 - 558502 - - - -1.4706 - 1.75 0.102 - 111.6 1 2 0 -0.0021 12 0 0 0 1.37E+07 1.64E+07 - - - 1.2278 0.985 221125_WJC_METTL3_EV_vs_WT_F05.13320.13320.3 0.171 Oct-44 K.TAQNHPMLVELK.N "sp|Q9Y4Z0|LSM4_HUMAN,tr|M0QXB0|M0QXB0_HUMAN,tr|V9GZ56|V9GZ56_HUMAN" 3 1379.7231 1.92 65238 13320 3 1379.720926 460.915 U6 snRNA-associated Sm-like protein LSm4 OS=Homo sapiens OX=9606 GN=LSM4 PE=1 SV=1 6.41 2500.2 - 3.64E+06 - - - -1.5909 - 1.693 0.157 - 121.4 1 2 0 -0.0022 12 0 0 0 7.90E+07 4.10E+07 - - - 1.7492 1 221125_WJC_METTL3_EV_vs_WT_F05.13326.13326.3 2.95E-10 22/68 K.MVMIQDGPQNTGADKPLR.L "sp|Q96AE4|FUBP1_HUMAN,tr|E9PEB5|E9PEB5_HUMAN" 2 1969.9714 0.94 65243 13326 3 1969.962878 657.6644 Far upstream element-binding protein 1 OS=Homo sapiens OX=9606 GN=FUBP1 PE=1 SV=3 5.71 2500.9 - 1.04E+06 - - - -4.3087 - 3.62 0.691 - 515.3 1 2 0 -0.0085 18 0 0 0 1.18E+07 1.26E+07 - - - 9.4451 1 221125_WJC_METTL3_EV_vs_WT_F05.13327.13327.3 9.87E-11 19/68 K.MVMIQDGPQNTGADK[136.11]PLR[166.11].L "sp|Q96AE4|FUBP1_HUMAN,tr|E9PEB5|E9PEB5_HUMAN" 2 1987.9938 0.94 65244 13327 3 1987.992607 663.6719 Far upstream element-binding protein 1 OS=Homo sapiens OX=9606 GN=FUBP1 PE=1 SV=3 5.71 2501 - 815387 - - - -0.6182 - 3.054 0.62 - 281.3 1 2 0 -0.0012 18 0 0 0 1.18E+07 1.26E+07 - - - 8.2321 0.9999 221125_WJC_METTL3_EV_vs_WT_F05.13329.13329.3 1.04E-05 16/44 K.KLLETEC[160.03]PQYIR.K sp|P05109|S10A8_HUMAN 1 1548.797 68.44 65246 13329 3 1548.792709 517.2729 Protein S100-A8 OS=Homo sapiens OX=9606 GN=S100A8 PE=1 SV=1 6.14 2501.3 - 574501 - - - -2.7796 - 2.705 0.457 - 493 1 2 0 -0.0043 12 0 0 0 9.82E+06 1.43E+05 - - - 6.3922 0.9999 221125_WJC_METTL3_EV_vs_WT_F05.13330.13330.2 5.29E-07 13/28 R.VSVGEFSAEGEGNSK.K "sp|Q9NUL3|STAU2_HUMAN,tr|E5RJN7|E5RJN7_HUMAN,tr|E7EVJ4|E7EVJ4_HUMAN,tr|E7EVI1|E7EVI1_HUMAN,tr|E7EPX0|E7EPX0_HUMAN" 5 1495.6791 1.93 65247 13330 2 1495.67736 748.8468 Double-stranded RNA-binding protein Staufen homolog 2 OS=Homo sapiens OX=9606 GN=STAU2 PE=1 SV=2 4.25 2501.4 - 422279 - - - -1.1413 - 2.485 0.568 - 738.3 1 2 0 -0.0017 15 0 0 0 3.91E+06 2.02E+06 - - - 5.4737 0.9998 221125_WJC_METTL3_EV_vs_WT_F05.13332.13332.2 1.93E-05 28-Nov K.LGTSGLNQPTFQQSK[136.11].M "sp|A5YKK6|CNOT1_HUMAN,tr|H3BR89|H3BR89_HUMAN,tr|H3BMH0|H3BMH0_HUMAN" 3 1612.83 0.93 65249 13332 2 1612.828152 807.4223 CCR4-NOT transcription complex subunit 1 OS=Homo sapiens OX=9606 GN=CNOT1 PE=1 SV=2 8.75 2501.7 - 280102 - - - -1.1675 - 2.174 0.49 - 246 1 2 0 -0.0019 15 0 0 0 2.27E+06 2.45E+06 - - - 4.5688 0.9851 221125_WJC_METTL3_EV_vs_WT_F05.13333.13333.2 4.25E-07 20-Aug R.QAHLC[160.03]VLASNC[160.03].D sp|P25398|RS12_HUMAN 1 1271.5751 - 65250 13333 2 1271.577564 636.7948 40S ribosomal protein S12 OS=Homo sapiens OX=9606 GN=RPS12 PE=1 SV=3 6.72 2501.8 - 204321 - - - 1.9558 - 1.936 0.566 - 210.1 1 1 0 0.0025 11 0 0 0 - - - - - 5.0078 0.9999 221125_WJC_METTL3_EV_vs_WT_F05.13339.13339.3 0.00712 Dec-40 R.R[166.11]EPTVSSFYVK[136.11].R "sp|Q9BVI4|NOC4L_HUMAN,tr|F5H303|F5H303_HUMAN" 2 1329.7048 0.98 65254 13339 3 1329.704369 444.2422 Nucleolar complex protein 4 homolog OS=Homo sapiens OX=9606 GN=NOC4L PE=1 SV=1 8.59 2502.5 - 823340 - - - -0.3031 - 2.083 0.382 - 130.8 1 2 0 -0.0004 11 0 0 0 8.92E+06 9.05E+06 - - - 4.8834 0.9993 221125_WJC_METTL3_EV_vs_WT_F05.13340.13340.3 0.0062 Nov-36 R.K[136.11]FDQLLAEEK[136.11].A "sp|Q7Z406|MYH14_HUMAN,sp|P35580|MYH10_HUMAN,sp|P35749|MYH11_HUMAN,sp|P35579|MYH9_HUMAN,tr|A1L2Z2|A1L2Z2_HUMAN,tr|A0A0C4DFM8|A0A0C4DFM8_HUMAN" 6 1235.6733 0.8 65255 13340 3 1235.671565 412.8984 Myosin-14 OS=Homo sapiens OX=9606 GN=MYH14 PE=1 SV=2 4.68 2502.7 - 808990 - - - -1.3661 - 1.98 0.281 - 149.6 1 2 0 -0.0017 10 0 0 0 7.55E+06 9.40E+06 - - - 3.6673 1 221125_WJC_METTL3_EV_vs_WT_F05.13341.13341.2 4.21E-08 17/36 R.MGGGGAMNMGDPYGSGGQK[136.11].F "sp|P23246|SFPQ_HUMAN,tr|H0Y9K7|H0Y9K7_HUMAN,tr|H0Y9U2|H0Y9U2_HUMAN" 3 1778.7266 0.8 65256 13341 2 1778.724005 890.3706 "Splicing factor, proline- and glutamine-rich OS=Homo sapiens OX=9606 GN=SFPQ PE=1 SV=2" 5.59 2502.8 - 748808 - - - -1.4443 - 3.209 0.746 - 493.7 1 2 0 -0.0026 19 0 0 0 4.56E+06 5.70E+06 - - - 7.4167 1 221125_WJC_METTL3_EV_vs_WT_F05.13342.13342.3 0.00021 15/40 K.AQFFLGTTNKR.A "sp|Q9NVT9|ARMC1_HUMAN,tr|E5RJ86|E5RJ86_HUMAN" 2 1281.683 1.59 65257 13342 3 1281.682322 428.2349 Armadillo repeat-containing protein 1 OS=Homo sapiens OX=9606 GN=ARMC1 PE=1 SV=1 11 2502.9 - 718781 - - - -0.5056 - 2.629 0.517 - 320.1 1 2 0 -0.0006 11 0 0 0 7.64E+06 4.80E+06 - - - 7.0498 0.9999 221125_WJC_METTL3_EV_vs_WT_F05.13343.13343.3 0.000359 Oct-40 R.REPTVSSFYVK.R "sp|Q9BVI4|NOC4L_HUMAN,tr|F5H303|F5H303_HUMAN" 2 1311.6823 1 65258 13343 3 1311.681979 438.2347 Nucleolar complex protein 4 homolog OS=Homo sapiens OX=9606 GN=NOC4L PE=1 SV=1 8.59 2503.1 - 671149 - - - -0.2462 - 2.146 0.369 - 200.6 1 2 0 -0.0003 11 0 0 0 9.04E+06 9.05E+06 - - - 4.8232 1 221125_WJC_METTL3_EV_vs_WT_F05.13344.13344.3 4.87E-07 Nov-56 R.AHTVVPLDDATQEYK.E "sp|Q9HCM9|TRI39_HUMAN,tr|A0A0G2JKY0|A0A0G2JKY0_HUMAN,tr|A0A096LP39|A0A096LP39_HUMAN,tr|A0A140TA46|A0A140TA46_HUMAN,tr|A2AAZ6|A2AAZ6_HUMAN,tr|H0Y735|H0Y735_HUMAN" 6 1685.8261 1.6 65259 13344 3 1685.825507 562.9493 E3 ubiquitin-protein ligase TRIM39 OS=Homo sapiens OX=9606 GN=TRIM39 PE=1 SV=2 4.54 2503.2 - 645654 - - - -0.331 - 2.56 0.506 - 130.4 1 2 0 -0.0006 15 0 0 0 5.78E+06 3.61E+06 - - - 6.6341 0.9792 221125_WJC_METTL3_EV_vs_WT_F05.13346.13346.3 0.000748 Nov-36 R.KFDQLLAEEK.A "sp|Q7Z406|MYH14_HUMAN,sp|P35580|MYH10_HUMAN,sp|P35749|MYH11_HUMAN,sp|P35579|MYH9_HUMAN,tr|A1L2Z2|A1L2Z2_HUMAN,tr|A0A0C4DFM8|A0A0C4DFM8_HUMAN" 6 1219.6449 0.83 65261 13346 3 1220.646317 407.5556 Myosin-14 OS=Homo sapiens OX=9606 GN=MYH14 PE=1 SV=2 4.68 2503.4 - 632978 - - - 821.1112 - 2.192 0.287 - 163.6 1 2 0 1.0015 10 0 0 0 7.55E+06 9.14E+06 - - - 3.7544 1 221125_WJC_METTL3_EV_vs_WT_F05.13347.13347.2 7.37E-10 17/24 R.KILQDGGLQVVEK.Q "sp|O43175|SERA_HUMAN,tr|A0A2C9F2M7|A0A2C9F2M7_HUMAN,tr|A0A286YFB2|A0A286YFB2_HUMAN,tr|A0A286YF34|A0A286YF34_HUMAN,tr|A0A286YFC8|A0A286YFC8_HUMAN,tr|A0A286YF22|A0A286YF22_HUMAN,tr|A0A286YFL2|A0A286YFL2_HUMAN,tr|A0A286YFA2|A0A286YFA2_HUMAN,tr|A0A286YFM8|A0A286YFM8_HUMAN,tr|A0A286YER3|A0A286YER3_HUMAN,tr|A0A286YFF3|A0A286YFF3_HUMAN,tr|A0A286YFK5|A0A286YFK5_HUMAN" 12 1425.8191 1.27 65262 13347 2 1425.822598 713.9168 D-3-phosphoglycerate dehydrogenase OS=Homo sapiens OX=9606 GN=PHGDH PE=1 SV=4 6.07 2503.6 - 542048 - - - 2.433 - 3.56 0.616 - 822 1 2 0 0.0035 13 0 0 0 5.29E+06 4.18E+06 - - - 6.8486 1 221125_WJC_METTL3_EV_vs_WT_F05.13348.13348.2 2.72E-11 21/36 R.MGGGGAMNMGDPYGSGGQK.F "sp|P23246|SFPQ_HUMAN,tr|H0Y9K7|H0Y9K7_HUMAN,tr|H0Y9U2|H0Y9U2_HUMAN" 3 1770.7124 0.8 65263 13348 2 1770.721186 886.3635 "Splicing factor, proline- and glutamine-rich OS=Homo sapiens OX=9606 GN=SFPQ PE=1 SV=2" 5.59 2503.7 - 531327 - - - 4.9765 - 3.513 0.79 - 919.7 1 2 0 0.0088 19 0 0 0 4.56E+06 5.70E+06 - - - 7.9623 0.9999 221125_WJC_METTL3_EV_vs_WT_F05.13351.13351.2 1.52E-06 28-Oct R.VSVGEFSAEGEGNSK[136.11].K "sp|Q9NUL3|STAU2_HUMAN,tr|E5RJN7|E5RJN7_HUMAN,tr|E7EVJ4|E7EVJ4_HUMAN,tr|E7EVI1|E7EVI1_HUMAN,tr|E7EPX0|E7EPX0_HUMAN" 5 1503.6933 1.93 65266 13351 2 1503.692474 752.8539 Double-stranded RNA-binding protein Staufen homolog 2 OS=Homo sapiens OX=9606 GN=STAU2 PE=1 SV=2 4.25 2504.1 - 361186 - - - -0.5274 - 2.13 0.495 - 356.2 1 2 0 -0.0008 15 0 0 0 3.91E+06 2.02E+06 - - - 4.5558 0.9999 221125_WJC_METTL3_EV_vs_WT_F05.13354.13354.2 1.98E-05 22-Dec R.AQVQEFC[160.03]DYGTK[136.11].E "sp|Q86U44|MTA70_HUMAN,tr|H0YFV6|H0YFV6_HUMAN" 2 1452.6435 0 65267 13354 2 1452.641997 727.329 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 4.37 2504.5 - 1.39E+06 - - - -1.0209 - 2.518 0.537 - 473.4 1 2 0 -0.0015 12 0 0 0 1.36E+05 9.38E+07 - - - 5.4366 0.9996 221125_WJC_METTL3_EV_vs_WT_F05.13358.13358.2 0.00204 18-Aug R.KFDQLLAEEK.A "sp|Q7Z406|MYH14_HUMAN,sp|P35580|MYH10_HUMAN,sp|P35749|MYH11_HUMAN,sp|P35579|MYH9_HUMAN,tr|A1L2Z2|A1L2Z2_HUMAN,tr|A0A0C4DFM8|A0A0C4DFM8_HUMAN" 6 1219.6449 1.15 65271 13358 2 1219.643582 610.8297 Myosin-14 OS=Homo sapiens OX=9606 GN=MYH14 PE=1 SV=2 4.68 2505 - 893058 - - - -1.0421 - 2.05 0.336 - 209.1 1 2 0 -0.0013 10 0 0 0 8.33E+06 7.25E+06 - - - 3.526 0.9999 221125_WJC_METTL3_EV_vs_WT_F05.13359.13359.2 6.81E-05 18-Dec R.K[136.11]FDQLLAEEK[136.11].A "sp|Q7Z406|MYH14_HUMAN,sp|P35580|MYH10_HUMAN,sp|P35749|MYH11_HUMAN,sp|P35579|MYH9_HUMAN,tr|A1L2Z2|A1L2Z2_HUMAN,tr|A0A0C4DFM8|A0A0C4DFM8_HUMAN" 6 1235.6733 1.17 65272 13359 2 1235.673301 618.8439 Myosin-14 OS=Homo sapiens OX=9606 GN=MYH14 PE=1 SV=2 4.68 2505.1 - 818483 - - - 0.0388 - 2.699 0.508 - 366.6 1 2 0 0 10 0 0 0 8.33E+06 7.10E+06 - - - 5.5645 0.999 221125_WJC_METTL3_EV_vs_WT_F05.13360.13360.3 0.00552 14/48 R.FHPASVLSQPQYK.K sp|Q9H6S0|YTDC2_HUMAN 1 1500.7725 1.78 65273 13360 3 1500.771187 501.2648 3'-5' RNA helicase YTHDC2 OS=Homo sapiens OX=9606 GN=YTHDC2 PE=1 SV=2 8.6 2505.2 - 743245 - - - -0.8842 - 2.329 0.224 - 260.5 1 2 0 -0.0013 13 0 0 0 8.22E+06 4.61E+06 - - - 3.3292 1 221125_WJC_METTL3_EV_vs_WT_F05.13361.13361.3 1.07E-06 14/40 K.AQFFLGTTNK[136.11]R[166.11].A "sp|Q9NVT9|ARMC1_HUMAN,tr|E5RJ86|E5RJ86_HUMAN" 2 1299.7054 1.59 65274 13361 3 1299.705553 434.2424 Armadillo repeat-containing protein 1 OS=Homo sapiens OX=9606 GN=ARMC1 PE=1 SV=1 11 2505.4 - 687958 - - - 0.0869 - 2.452 0.535 - 234.6 1 2 0 0.0001 11 0 0 0 7.64E+06 4.80E+06 - - - 7.0526 1 221125_WJC_METTL3_EV_vs_WT_F05.13362.13362.3 3.22E-07 24/64 K.QSAQLTALAAQQQAAGK.E sp|Q96A49|SYAP1_HUMAN 1 1683.8904 1.42 65275 13362 3 1683.889747 562.3041 Synapse-associated protein 1 OS=Homo sapiens OX=9606 GN=SYAP1 PE=1 SV=1 8.75 2505.5 - 612830 - - - -0.386 - 3.974 0.512 - 1100.5 1 2 0 -0.0006 17 0 0 0 2.50E+08 1.77E+08 - - - 7.7338 0.9998 221125_WJC_METTL3_EV_vs_WT_F05.13363.13363.2 0.0648 16/32 K.TTTLSGTAPAAGVVPSR[166.11].V "sp|P27816|MAP4_HUMAN,tr|H0Y2V1|H0Y2V1_HUMAN,tr|E7EVA0|E7EVA0_HUMAN,tr|F8W9U4|F8W9U4_HUMAN,tr|H7C4C5|H7C4C5_HUMAN,tr|A0A804HKE7|A0A804HKE7_HUMAN,tr|B5MEG9|B5MEG9_HUMAN" 7 1594.8554 0.34 65276 13363 2 1594.856261 798.435 Microtubule-associated protein 4 OS=Homo sapiens OX=9606 GN=MAP4 PE=1 SV=3 9.41 2505.6 - 479856 - - - 0.5367 - 2.419 0.457 - 590.1 1 2 0 0.0009 17 0 0 0 2.55E+06 7.49E+06 - - - 4.5879 0.9209 221125_WJC_METTL3_EV_vs_WT_F05.13364.13364.3 7.22E-05 14/44 R.HVFLTGPPGVGK.T "sp|Q9BSD7|NTPCR_HUMAN,tr|Q5TDF0|Q5TDF0_HUMAN" 2 1207.6713 1.3 65277 13364 3 1209.6759 403.5644 Cancer-related nucleoside-triphosphatase OS=Homo sapiens OX=9606 GN=NTPCR PE=1 SV=1 8.76 2505.8 - 475850 - - - 1659.8531 - 2.815 0.44 - 314.5 1 2 0 2.0046 12 0 0 0 1.89E+07 1.45E+07 - - - 5.7591 1 221125_WJC_METTL3_EV_vs_WT_F05.13365.13365.2 4.79E-10 20/32 K.QSAQLTALAAQQQAAGK.E sp|Q96A49|SYAP1_HUMAN 1 1683.8904 1.34 65278 13365 2 1683.891845 842.9525 Synapse-associated protein 1 OS=Homo sapiens OX=9606 GN=SYAP1 PE=1 SV=1 8.75 2505.9 - 359403 - - - 0.8599 - 3.993 0.634 - 1523.2 1 2 0 0.0014 17 0 0 0 1.63E+08 1.21E+08 - - - 7.1272 1 221125_WJC_METTL3_EV_vs_WT_F05.13366.13366.2 4.85E-09 26-Nov R.DTQTSITDSC[160.03]AVYR.V sp|Q9Y5M8|SRPRB_HUMAN 1 1615.7148 1.29 65279 13366 2 1615.712264 808.8647 Signal recognition particle receptor subunit beta OS=Homo sapiens OX=9606 GN=SRPRB PE=1 SV=3 4.21 2506 - 340843 - - - -1.5702 - 2.695 0.685 - 338.8 1 2 0 -0.0025 14 0 0 0 2.68E+06 2.08E+06 - - - 6.5875 1 221125_WJC_METTL3_EV_vs_WT_F05.13373.13373.2 0.000369 13/28 K.VEYTLGEESEAPGQR[166.11].A "sp|Q04637|IF4G1_HUMAN,tr|H7C0V6|H7C0V6_HUMAN,tr|E7EUU4|E7EUU4_HUMAN,tr|E9PGM1|E9PGM1_HUMAN,tr|E7EX73|E7EX73_HUMAN,tr|A0A7I2Y1C3|A0A7I2Y1C3_HUMAN" 6 1673.7772 0.95 65285 13373 2 1673.773553 837.8959 Eukaryotic translation initiation factor 4 gamma 1 OS=Homo sapiens OX=9606 GN=EIF4G1 PE=1 SV=4 4.09 2507 - 774598 - - - -2.1873 - 2.553 0.624 - 465.1 1 2 0 -0.0037 15 0 0 0 5.70E+06 6.01E+06 - - - 5.953 1 221125_WJC_METTL3_EV_vs_WT_F05.13374.13374.3 3.45E-09 19/64 K.QSAQLTALAAQQQAAGK[136.11].E sp|Q96A49|SYAP1_HUMAN 1 1691.9046 1.42 65286 13374 3 1691.904731 564.9755 Synapse-associated protein 1 OS=Homo sapiens OX=9606 GN=SYAP1 PE=1 SV=1 8.75 2507 - 3.45E+06 - - - 0.0792 - 3.639 0.558 - 667 1 2 0 0.0001 17 0 0 0 2.50E+08 1.77E+08 - - - 8.0244 1 221125_WJC_METTL3_EV_vs_WT_F05.13376.13376.2 4.04E-10 19/32 K.QSAQLTALAAQQQAAGK[136.11].E sp|Q96A49|SYAP1_HUMAN 1 1691.9046 1.34 65288 13376 2 1691.903894 846.9596 Synapse-associated protein 1 OS=Homo sapiens OX=9606 GN=SYAP1 PE=1 SV=1 8.75 2507.2 - 2.06E+06 - - - -0.4155 - 3.919 0.661 - 1511.7 1 2 0 -0.0007 17 0 0 0 1.63E+08 1.21E+08 - - - 7.2809 0.9999 221125_WJC_METTL3_EV_vs_WT_F05.13379.13379.2 1.20E-05 22-Dec R.ALEEANTELEVK.L "sp|Q04695|K1C17_HUMAN,tr|K7EPJ9|K7EPJ9_HUMAN" 2 1344.6773 58.85 65291 13379 2 1344.6781 673.3459 "Keratin, type I cytoskeletal 17 OS=Homo sapiens OX=9606 GN=KRT17 PE=1 SV=2" 4.09 2507.5 - 843350 - - - 0.6128 - 2.647 0.474 - 417.3 1 2 0 0.0008 12 0 0 0 5.15E+06 8.75E+04 - - - 5.103 0.9999 221125_WJC_METTL3_EV_vs_WT_F05.13381.13381.2 0.000541 13/26 K.AEAENTSEVSTVLK.L sp|Q16512|PKN1_HUMAN 1 1476.7308 1.73 65293 13381 2 1476.730416 739.3727 Serine\threonine-protein kinase N1 OS=Homo sapiens OX=9606 GN=PKN1 PE=1 SV=2 4.25 2507.7 - 763808 - - - -0.2384 - 2.828 0.497 - 507.5 1 2 0 -0.0004 14 0 0 0 4.46E+06 2.57E+06 - - - 5.3205 1 221125_WJC_METTL3_EV_vs_WT_F05.13382.13382.2 8.70E-05 16/22 R.HVFLTGPPGVGK[136.11].T "sp|Q9BSD7|NTPCR_HUMAN,tr|Q5TDF0|Q5TDF0_HUMAN" 2 1215.6855 5.96 65294 13382 2 1215.686348 608.85 Cancer-related nucleoside-triphosphatase OS=Homo sapiens OX=9606 GN=NTPCR PE=1 SV=1 8.76 2507.9 - 755251 - - - 0.6622 - 2.676 0.563 - 681 1 2 0 0.0008 12 0 0 0 4.30E+07 7.22E+06 - - - 5.789 1 221125_WJC_METTL3_EV_vs_WT_F05.13383.13383.2 6.10E-10 15/28 K.VEYTLGEESEAPGQR.A "sp|Q04637|IF4G1_HUMAN,tr|H7C0V6|H7C0V6_HUMAN,tr|E7EUU4|E7EUU4_HUMAN,tr|E9PGM1|E9PGM1_HUMAN,tr|E7EX73|E7EX73_HUMAN,tr|A0A7I2Y1C3|A0A7I2Y1C3_HUMAN" 6 1663.7689 0.95 65295 13383 2 1663.770555 832.8917 Eukaryotic translation initiation factor 4 gamma 1 OS=Homo sapiens OX=9606 GN=EIF4G1 PE=1 SV=4 4.09 2508 - 703958 - - - 0.9683 - 3.245 0.674 - 721.8 1 2 0 0.0016 15 0 0 0 5.70E+06 6.01E+06 - - - 6.9127 0.9979 221125_WJC_METTL3_EV_vs_WT_F05.13385.13385.3 0.000102 Nov-60 K.FADLSEAANRNNDALR.Q "sp|P08670|VIME_HUMAN,tr|B0YJC5|B0YJC5_HUMAN,tr|B0YJC4|B0YJC4_HUMAN" 3 1775.8551 0.78 65297 13385 3 1775.857559 592.959 Vimentin OS=Homo sapiens OX=9606 GN=VIM PE=1 SV=4 4.56 2508.2 - 612850 - - - 1.3993 - 2.017 0.339 - 189.9 1 2 1 0.0025 16 0 0 0 1.89E+06 2.43E+06 - - - 4.1191 0.9996 221125_WJC_METTL3_EV_vs_WT_F05.13386.13386.3 0.000102 13/52 K.LNYEENK[136.11]EESLLEK[136.11].R sp|O95347|SMC2_HUMAN 1 1752.8753 0.77 65298 13386 3 1752.875769 585.299 Structural maintenance of chromosomes protein 2 OS=Homo sapiens OX=9606 GN=SMC2 PE=1 SV=2 4.33 2508.4 - 594946 - - - 0.2904 - 2.576 0.38 - 244.7 1 2 1 0.0005 14 0 0 0 1.27E+06 1.66E+06 - - - 5.2911 0.9997 221125_WJC_METTL3_EV_vs_WT_F05.13388.13388.3 0.000398 Nov-64 K.TTTLSGTAPAAGVVPSR[166.11].V "sp|P27816|MAP4_HUMAN,tr|H0Y2V1|H0Y2V1_HUMAN,tr|E7EVA0|E7EVA0_HUMAN,tr|F8W9U4|F8W9U4_HUMAN,tr|H7C4C5|H7C4C5_HUMAN,tr|A0A804HKE7|A0A804HKE7_HUMAN,tr|B5MEG9|B5MEG9_HUMAN" 7 1594.8554 0.27 65300 13388 3 1594.859264 532.6257 Microtubule-associated protein 4 OS=Homo sapiens OX=9606 GN=MAP4 PE=1 SV=3 9.41 2508.6 - 385951 - - - 2.4197 - 2.443 0.388 - 149.9 1 2 0 0.0039 17 0 0 0 4.40E+05 1.64E+06 - - - 5.1213 0.9945 221125_WJC_METTL3_EV_vs_WT_F05.13390.13390.3 0.00583 Aug-36 K.ISFDDQHFEK.F "sp|Q12756|KIF1A_HUMAN,tr|A0A3B3ITW6|A0A3B3ITW6_HUMAN,tr|A0A3B3ITF7|A0A3B3ITF7_HUMAN,tr|A0A3B3ITE5|A0A3B3ITE5_HUMAN,tr|A0A3B3IUA1|A0A3B3IUA1_HUMAN,tr|A0A3B3IT28|A0A3B3IT28_HUMAN,tr|A0A3F2YNW9|A0A3F2YNW9_HUMAN,tr|A0A3B3IU40|A0A3B3IU40_HUMAN,tr|A0A3B3ITK3|A0A3B3ITK3_HUMAN" 9 1264.5724 0.77 65302 13390 3 1264.57002 422.5314 Kinesin-like protein KIF1A OS=Homo sapiens OX=9606 GN=KIF1A PE=1 SV=2 4.54 2508.9 - 333404 - - - -1.8955 - 1.277 0.291 - 74.6 1 2 0 -0.0024 10 0 0 0 1.58E+06 2.06E+06 - - - 2.4978 0.9999 221125_WJC_METTL3_EV_vs_WT_F05.13391.13391.2 9.65E-06 26-Sep R.DTQTSITDSC[160.03]AVYR[166.11].V sp|Q9Y5M8|SRPRB_HUMAN 1 1625.7231 1.29 65303 13391 2 1625.723029 813.8688 Signal recognition particle receptor subunit beta OS=Homo sapiens OX=9606 GN=SRPRB PE=1 SV=3 4.21 2509 - 330649 - - - -0.0258 - 1.911 0.536 - 251 1 2 0 0 14 0 0 0 2.68E+06 2.08E+06 - - - 4.6251 0.9985 221125_WJC_METTL3_EV_vs_WT_F05.13393.13393.2 0.0021 24-Jul R.K[136.11]ILQDGGLQVVEK[136.11].Q "sp|O43175|SERA_HUMAN,tr|A0A2C9F2M7|A0A2C9F2M7_HUMAN,tr|A0A286YFB2|A0A286YFB2_HUMAN,tr|A0A286YF34|A0A286YF34_HUMAN,tr|A0A286YFC8|A0A286YFC8_HUMAN,tr|A0A286YF22|A0A286YF22_HUMAN,tr|A0A286YFL2|A0A286YFL2_HUMAN,tr|A0A286YFA2|A0A286YFA2_HUMAN,tr|A0A286YFM8|A0A286YFM8_HUMAN,tr|A0A286YER3|A0A286YER3_HUMAN,tr|A0A286YFF3|A0A286YFF3_HUMAN,tr|A0A286YFK5|A0A286YFK5_HUMAN" 12 1441.8475 1.27 65304 13393 2 1441.849086 721.931 D-3-phosphoglycerate dehydrogenase OS=Homo sapiens OX=9606 GN=PHGDH PE=1 SV=4 6.07 2509.2 - 153421 - - - 1.0799 - 1.365 0.329 - 114 1 2 0 0.0016 13 0 0 0 5.29E+06 4.18E+06 - - - 2.2691 0.985 221125_WJC_METTL3_EV_vs_WT_F05.13394.13394.3 0.00154 13/56 K.VEYTLGEESEAPGQR[166.11].A "sp|Q04637|IF4G1_HUMAN,tr|H7C0V6|H7C0V6_HUMAN,tr|E7EUU4|E7EUU4_HUMAN,tr|E9PGM1|E9PGM1_HUMAN,tr|E7EX73|E7EX73_HUMAN,tr|A0A7I2Y1C3|A0A7I2Y1C3_HUMAN" 6 1673.7772 1.01 65305 13394 3 1674.780773 558.933 Eukaryotic translation initiation factor 4 gamma 1 OS=Homo sapiens OX=9606 GN=EIF4G1 PE=1 SV=4 4.09 2509.3 - 480053 - - - 599.5774 - 2.503 0.269 - 171.1 1 2 0 1.0036 15 0 0 0 1.49E+06 1.48E+06 - - - 3.6552 0.9966 221125_WJC_METTL3_EV_vs_WT_F05.13395.13395.3 0.0985 Aug-44 R.ELMAWNQAENRR.L sp|Q9BYN8|RT26_HUMAN 1 1516.7205 1.27 65306 13395 3 1516.72197 506.5808 "28S ribosomal protein S26, mitochondrial OS=Homo sapiens OX=9606 GN=MRPS26 PE=1 SV=1" 6.24 2509.4 - 1.31E+06 - - - 0.9725 - 1.483 0.261 - 110.4 1 2 0 0.0015 12 0 0 0 6.88E+06 5.40E+06 - - - 2.5418 0.9993 221125_WJC_METTL3_EV_vs_WT_F05.13396.13396.3 0.146 Dec-40 K.KLVESLPQEIK.A "sp|P52815|RM12_HUMAN,tr|B4DLN1|B4DLN1_HUMAN" 2 1282.7497 2 65307 13396 3 1282.75091 428.5905 "39S ribosomal protein L12, mitochondrial OS=Homo sapiens OX=9606 GN=MRPL12 PE=1 SV=2" 6.14 2509.5 - 1.20E+06 - - - 0.9799 - 1.799 0.306 - 252.8 1 2 0 0.0013 11 0 0 0 7.28E+07 3.64E+07 - - - 3.6195 1 221125_WJC_METTL3_EV_vs_WT_F05.13397.13397.2 1.03E-09 13/22 K.YSQVLANGLDNK[136.11].L "sp|P62269|RS18_HUMAN,tr|J3JS69|J3JS69_HUMAN" 2 1328.6816 0.94 65308 13397 2 1328.682863 665.3481 40S ribosomal protein S18 OS=Homo sapiens OX=9606 GN=RPS18 PE=1 SV=3 5.83 2509.6 - 1.04E+06 - - - 0.9656 - 2.745 0.629 - 521.1 1 2 0 0.0013 12 0 0 0 6.42E+06 6.79E+06 - - - 6.3433 0.9995 221125_WJC_METTL3_EV_vs_WT_F05.13398.13398.3 0.00179 Nov-44 R.ELMAWNQAENR[166.11]R[166.11].L sp|Q9BYN8|RT26_HUMAN 1 1536.737 1.4 65309 13398 3 1536.736153 513.253 "28S ribosomal protein S26, mitochondrial OS=Homo sapiens OX=9606 GN=MRPS26 PE=1 SV=1" 6.24 2509.7 - 995720 - - - -0.5739 - 1.957 0.308 - 182.2 1 2 0 -0.0009 12 0 0 0 7.54E+06 5.40E+06 - - - 3.8347 1 221125_WJC_METTL3_EV_vs_WT_F05.13399.13399.2 3.37E-08 14/22 K.YSQVLANGLDNK.L "sp|P62269|RS18_HUMAN,tr|J3JS69|J3JS69_HUMAN" 2 1320.6674 0.9 65310 13399 2 1320.669289 661.341 40S ribosomal protein S18 OS=Homo sapiens OX=9606 GN=RPS18 PE=1 SV=3 5.83 2509.8 - 968282 - - - 1.4455 - 2.819 0.666 - 632.4 1 2 0 0.0019 12 0 0 0 6.42E+06 7.15E+06 - - - 6.6864 0.9999 221125_WJC_METTL3_EV_vs_WT_F05.13400.13400.3 0.000422 15/40 K.SNFAEALAAHK.Y "sp|P07237|PDIA1_HUMAN,tr|A0A7P0TA97|A0A7P0TA97_HUMAN,tr|A0A7P0T8C0|A0A7P0T8C0_HUMAN,tr|H7BZ94|H7BZ94_HUMAN,tr|A0A7P0Z4B2|A0A7P0Z4B2_HUMAN,tr|A0A7P0TA71|A0A7P0TA71_HUMAN,tr|I3L4M2|I3L4M2_HUMAN,tr|A0A7P0T9D6|A0A7P0T9D6_HUMAN,tr|A0A7P0T9K9|A0A7P0T9K9_HUMAN,tr|H0Y3Z3|H0Y3Z3_HUMAN,tr|A0A7P0Z4S2|A0A7P0Z4S2_HUMAN,tr|I3NI03|I3NI03_HUMAN,tr|A0A7P0TA35|A0A7P0TA35_HUMAN,tr|A0A7P0TAX9|A0A7P0TAX9_HUMAN,tr|I3L1Y5|I3L1Y5_HUMAN,tr|I3L514|I3L514_HUMAN,tr|A0A7P0Z476|A0A7P0Z476_HUMAN,tr|A0A7P0Z4F8|A0A7P0Z4F8_HUMAN,tr|A0A7P0TBP8|A0A7P0TBP8_HUMAN,tr|A0A7P0TB26|A0A7P0TB26_HUMAN,tr|A0A7P0T9U6|A0A7P0T9U6_HUMAN,tr|A0A7P0T9E3|A0A7P0T9E3_HUMAN,tr|A0A7P0TBA3|A0A7P0TBA3_HUMAN,tr|I3L0S0|I3L0S0_HUMAN,tr|I3L3P5|I3L3P5_HUMAN,tr|A0A7P0T940|A0A7P0T940_HUMAN,tr|A0A7P0T8J3|A0A7P0T8J3_HUMAN,tr|A0A7P0Z4J0|A0A7P0Z4J0_HUMAN,tr|A0A7P0T9S9|A0A7P0T9S9_HUMAN,tr|A0A7P0T8X1|A0A7P0T8X1_HUMAN,tr|I3L3U6|I3L3U6_HUMAN" 31 1157.5829 1.37 65311 13400 3 1157.583538 386.8683 Protein disulfide-isomerase OS=Homo sapiens OX=9606 GN=P4HB PE=1 SV=3 6.47 2509.9 - 965904 - - - 0.5321 - 2.293 0.435 - 372.7 1 2 0 0.0006 11 0 0 0 4.07E+06 2.97E+06 - - - 5.7471 0.9999 221125_WJC_METTL3_EV_vs_WT_F05.13401.13401.3 8.08E-06 17/52 K.NQTSLLGEPPKEIR.L sp|Q9HCJ3|RAVR2_HUMAN 1 1580.8522 0.9 65312 13401 3 1580.853755 527.958 Ribonucleoprotein PTB-binding 2 OS=Homo sapiens OX=9606 GN=RAVER2 PE=1 SV=2 6.14 2510 - 819080 - - - 0.9704 - 2.832 0.486 - 460.6 1 2 1 0.0015 14 0 0 0 7.71E+06 8.56E+06 - - - 6.7244 0.9998 221125_WJC_METTL3_EV_vs_WT_F05.13403.13403.2 3.95E-08 13/22 K.DSAQNSVIIVDK.N "sp|P02786|TFR1_HUMAN,tr|G3V0E5|G3V0E5_HUMAN" 2 1287.667 1.64 65314 13403 2 1287.669451 644.8408 Transferrin receptor protein 1 OS=Homo sapiens OX=9606 GN=TFRC PE=1 SV=2 4.21 2510.2 - 636993 - - - 1.8685 - 2.68 0.522 - 842.7 1 2 0 0.0024 12 0 0 0 4.63E+06 2.81E+06 - - - 5.4896 0.9996 221125_WJC_METTL3_EV_vs_WT_F05.13404.13404.3 0.0101 14/44 R.VTEQDKAILQLK.Q sp|Q96FZ7|CHMP6_HUMAN 1 1384.7926 1.8 65315 13404 3 1384.793392 462.6048 Charged multivesicular body protein 6 OS=Homo sapiens OX=9606 GN=CHMP6 PE=1 SV=3 6.04 2510.3 - 576380 - - - 0.5864 - 2.815 0.347 - 318 1 2 1 0.0008 12 0 0 0 3.84E+06 2.13E+06 - - - 5.2772 0.9465 221125_WJC_METTL3_EV_vs_WT_F05.13405.13405.3 0.698 Nov-60 M.AGTNALLMLENFIDGK.F sp|Q9H2A2|AL8A1_HUMAN 1 1705.8709 0.79 65316 13405 3 1705.873789 569.6309 2-aminomuconic semialdehyde dehydrogenase OS=Homo sapiens OX=9606 GN=ALDH8A1 PE=1 SV=1 4.37 2510.5 - 573494 - - - 1.6895 - 2.061 0.074 - 135 2 2 0 0.0029 16 0 0 0 6.57E+06 8.30E+06 - - - 1.0805 0.9334 221125_WJC_METTL3_EV_vs_WT_F05.13408.13408.3 0.341 Oct-56 R.NPFEAIRPGSAQQVK.T "sp|Q9HAW4|CLSPN_HUMAN,tr|E7ESG2|E7ESG2_HUMAN" 2 1640.8635 188.02 65319 13408 3 1640.866944 547.9618 Claspin OS=Homo sapiens OX=9606 GN=CLSPN PE=1 SV=3 8.75 2510.9 - 353147 - - - 2.1269 - 1.684 0.108 - 136.9 1 2 0 0.0035 15 0 0 0 5.69E+07 3.03E+05 - - - 1.1031 1 221125_WJC_METTL3_EV_vs_WT_F05.13410.13410.3 1.39E-08 17/52 R.LADMHSTEISLQQR.L "sp|O75694|NU155_HUMAN,tr|E9PF10|E9PF10_HUMAN" 2 1627.7988 1.5 65321 13410 3 1627.800851 543.6069 Nuclear pore complex protein Nup155 OS=Homo sapiens OX=9606 GN=NUP155 PE=1 SV=1 5.32 2511.1 - 343585 - - - 1.2569 - 2.951 0.604 - 349.3 1 2 0 0.002 14 0 0 0 9.76E+06 6.53E+06 - - - 8.1493 1 221125_WJC_METTL3_EV_vs_WT_F05.13417.13417.2 6.59E-08 16/30 R.ATSTATSGFAGAIGQK[136.11].L "sp|P51659|DHB4_HUMAN,tr|A0A2R8Y7L2|A0A2R8Y7L2_HUMAN,tr|A0A2R8YD50|A0A2R8YD50_HUMAN,tr|A0A804HIR1|A0A804HIR1_HUMAN,tr|E7ET17|E7ET17_HUMAN,tr|E7ER27|E7ER27_HUMAN,tr|E7EPL9|E7EPL9_HUMAN,tr|A0A804HKU2|A0A804HKU2_HUMAN,tr|A0A804HK65|A0A804HK65_HUMAN" 9 1474.7507 0.46 65327 13417 2 1474.749782 738.3826 Peroxisomal multifunctional enzyme type 2 OS=Homo sapiens OX=9606 GN=HSD17B4 PE=1 SV=3 8.8 2511.9 - 1.52E+06 - - - -0.6374 - 3.143 0.638 - 1033.6 1 2 0 -0.0009 16 0 0 0 5.53E+06 1.21E+07 - - - 6.5684 1 221125_WJC_METTL3_EV_vs_WT_F05.13418.13418.3 8.38E-08 14/40 K.GNEFEDYC[160.03]LK[136.11]R[166.11].E "sp|P26196|DDX6_HUMAN,tr|Q8IV96|Q8IV96_HUMAN" 2 1447.6521 1.08 65328 13418 3 1447.652543 483.558 Probable ATP-dependent RNA helicase DDX6 OS=Homo sapiens OX=9606 GN=DDX6 PE=1 SV=2 4.68 2512 - 1.28E+06 - - - 0.3171 - 2.602 0.585 - 394.5 1 2 0 0.0005 11 0 0 0 4.84E+07 4.50E+07 - - - 7.7787 0.9997 221125_WJC_METTL3_EV_vs_WT_F05.13419.13419.3 0.000451 Dec-40 K.GNEFEDYC[160.03]LKR.E "sp|P26196|DDX6_HUMAN,tr|Q8IV96|Q8IV96_HUMAN" 2 1429.6296 1.08 65329 13419 3 1429.630466 477.5505 Probable ATP-dependent RNA helicase DDX6 OS=Homo sapiens OX=9606 GN=DDX6 PE=1 SV=2 4.68 2512 - 990959 - - - 0.596 - 2.31 0.301 - 278.8 1 2 0 0.0009 11 0 0 0 4.84E+07 4.50E+07 - - - 4.2741 1 221125_WJC_METTL3_EV_vs_WT_F05.13420.13420.3 3.11E-06 18/52 R.LADMHSTEISLQQR[166.11].L "sp|O75694|NU155_HUMAN,tr|E9PF10|E9PF10_HUMAN" 2 1637.8071 1.56 65330 13420 3 1637.808969 546.943 Nuclear pore complex protein Nup155 OS=Homo sapiens OX=9606 GN=NUP155 PE=1 SV=1 5.32 2512.1 - 911982 - - - 1.1564 - 3.07 0.516 - 509 1 2 0 0.0019 14 0 0 0 9.76E+06 6.27E+06 - - - 7.2733 0.9996 221125_WJC_METTL3_EV_vs_WT_F05.13421.13421.3 0.00148 Nov-52 R.TYSLGSALRPSTSR.S "sp|P08670|VIME_HUMAN,tr|B0YJC4|B0YJC4_HUMAN,tr|A0A1B0GVG8|A0A1B0GVG8_HUMAN,tr|A0A1B0GTT5|A0A1B0GTT5_HUMAN" 4 1494.7791 4.08 65331 13421 3 1494.780685 499.267 Vimentin OS=Homo sapiens OX=9606 GN=VIM PE=1 SV=4 10.83 2512.2 - 866223 - - - 1.0898 - 1.714 0.371 - 128.7 1 2 0 0.0016 14 0 0 0 2.60E+07 6.37E+06 - - - 4.1078 1 221125_WJC_METTL3_EV_vs_WT_F05.13423.13423.2 0.00025 18/20 K.KLVESLPQEIK.A "sp|P52815|RM12_HUMAN,tr|B4DLN1|B4DLN1_HUMAN" 2 1282.7497 2.41 65333 13423 2 1282.74966 642.3821 "39S ribosomal protein L12, mitochondrial OS=Homo sapiens OX=9606 GN=MRPL12 PE=1 SV=2" 6.14 2512.4 - 840155 - - - 0.0055 - 3.207 0.523 - 1160.6 1 2 0 0 11 0 0 0 2.74E+07 1.14E+07 - - - 6.0564 0.9996 221125_WJC_METTL3_EV_vs_WT_F05.13424.13424.3 0.00131 Nov-40 K.SK[136.11]DTYLLYEGR[166.11].G "sp|Q9BSH4|TACO1_HUMAN,tr|A0A804HJB7|A0A804HJB7_HUMAN" 2 1361.6946 0.72 65334 13424 3 1361.695657 454.9055 Translational activator of cytochrome c oxidase 1 OS=Homo sapiens OX=9606 GN=TACO1 PE=1 SV=1 5.79 2512.6 - 545893 - - - 0.7755 - 2.167 0.41 - 208.3 1 2 1 0.0011 11 0 0 0 2.35E+06 3.24E+06 - - - 5.3077 0.9379 221125_WJC_METTL3_EV_vs_WT_F05.13425.13425.3 0.501 Oct-44 R.VTEQDK[136.11]AILQLK[136.11].Q sp|Q96FZ7|CHMP6_HUMAN 1 1400.821 1.8 65335 13425 3 1400.821585 467.9476 Charged multivesicular body protein 6 OS=Homo sapiens OX=9606 GN=CHMP6 PE=1 SV=3 6.04 2512.6 - 458637 - - - 0.4319 - 1.397 0.191 - 69.5 1 2 1 0.0006 12 0 0 0 3.84E+06 2.13E+06 - - - 1.596 0.9998 221125_WJC_METTL3_EV_vs_WT_F05.13426.13426.2 0.000167 24-Sep K.ETGSISAPSEC[160.03]FR.Q sp|Q9UQR0|SCML2_HUMAN 1 1439.6351 0.57 65336 13426 2 1439.633519 720.8248 Sex comb on midleg-like protein 2 OS=Homo sapiens OX=9606 GN=SCML2 PE=1 SV=1 4.53 2512.8 - 224172 - - - -1.094 - 1.751 0.529 - 196.4 1 2 0 -0.0016 13 0 0 0 9.69E+05 1.69E+06 - - - 4.3854 1 221125_WJC_METTL3_EV_vs_WT_F05.13432.13432.3 5.57E-08 16/52 R.NALQQENHIIDGVK.V "sp|Q9GZT3|SLIRP_HUMAN,tr|H0YJW7|H0YJW7_HUMAN,tr|A0A087WUN7|A0A087WUN7_HUMAN,tr|G3V2S9|G3V2S9_HUMAN,tr|H0YJ40|H0YJ40_HUMAN,tr|G3V4X6|G3V4X6_HUMAN" 6 1577.8162 1.43 65340 13432 3 1577.817081 526.946 "SRA stem-loop-interacting RNA-binding protein, mitochondrial OS=Homo sapiens OX=9606 GN=SLIRP PE=1 SV=1" 5.32 2513.6 - 5.48E+06 - - - 0.578 - 2.884 0.512 - 355.2 1 2 0 0.0009 14 0 0 0 2.73E+09 1.91E+09 - - - 7.0628 1 221125_WJC_METTL3_EV_vs_WT_F05.13433.13433.3 3.46E-07 16/52 R.NALQQENHIIDGVK[136.11].V "sp|Q9GZT3|SLIRP_HUMAN,tr|H0YJW7|H0YJW7_HUMAN,tr|A0A087WUN7|A0A087WUN7_HUMAN,tr|G3V2S9|G3V2S9_HUMAN,tr|H0YJ40|H0YJ40_HUMAN,tr|G3V4X6|G3V4X6_HUMAN" 6 1585.8304 1.43 65341 13433 3 1585.829469 529.6174 "SRA stem-loop-interacting RNA-binding protein, mitochondrial OS=Homo sapiens OX=9606 GN=SLIRP PE=1 SV=1" 5.32 2513.6 - 5.15E+06 - - - -0.5675 - 3.219 0.51 - 364.2 1 2 0 -0.0009 14 0 0 0 2.73E+09 1.91E+09 - - - 7.3326 0.9997 221125_WJC_METTL3_EV_vs_WT_F05.13434.13434.3 1.43E-05 Dec-48 K.SVEEGK[136.11]IDGIIDK[136.11].T sp|Q96A49|SYAP1_HUMAN 1 1417.7635 0.7 65342 13434 3 1417.763705 473.5951 Synapse-associated protein 1 OS=Homo sapiens OX=9606 GN=SYAP1 PE=1 SV=1 4.32 2513.7 - 1.88E+06 - - - 0.127 - 2.107 0.461 - 109.8 1 2 1 0.0002 13 0 0 0 3.38E+06 4.82E+06 - - - 5.7003 0.9994 221125_WJC_METTL3_EV_vs_WT_F05.13436.13436.3 0.000323 Oct-48 K.SVEEGKIDGIIDK.T sp|Q96A49|SYAP1_HUMAN 1 1401.7351 -1 65344 13436 3 1401.736261 468.2523 Synapse-associated protein 1 OS=Homo sapiens OX=9606 GN=SYAP1 PE=1 SV=1 4.32 2513.8 - 1.60E+06 - - - 0.8104 - 1.883 0.427 - 76 1 2 1 0.0011 13 0 0 0 0.00E+00 0.00E+00 - - - 5.0162 1 221125_WJC_METTL3_EV_vs_WT_F05.13438.13438.3 3.83E-06 Oct-52 K.IEVLQQHENEDIYK[136.11].L "sp|O00505|IMA4_HUMAN,tr|H0Y4S9|H0Y4S9_HUMAN" 2 1764.8774 0.81 65346 13438 3 1764.87617 589.2997 Importin subunit alpha-4 OS=Homo sapiens OX=9606 GN=KPNA3 PE=1 SV=2 4.4 2513.9 - 1.39E+06 - - - -0.685 - 2.661 0.441 - 131.8 1 2 0 -0.0012 14 0 0 0 1.06E+07 1.31E+07 - - - 6.0573 0.9999 221125_WJC_METTL3_EV_vs_WT_F05.13440.13440.2 0.00809 13/20 K.K[136.11]LVESLPQEIK[136.11].A "sp|P52815|RM12_HUMAN,tr|B4DLN1|B4DLN1_HUMAN" 2 1298.7781 2.41 65348 13440 2 1298.778436 650.3963 "39S ribosomal protein L12, mitochondrial OS=Homo sapiens OX=9606 GN=MRPL12 PE=1 SV=2" 6.14 2514.2 - 770955 - - - 0.2949 - 2.631 0.472 - 498.7 1 2 0 0.0004 11 0 0 0 2.74E+07 1.14E+07 - - - 5.144 1 221125_WJC_METTL3_EV_vs_WT_F05.13441.13441.3 6.39E-07 20/60 R.LAQMISDHNDADFEEK.V "sp|Q14157|UBP2L_HUMAN,tr|Q5VU78|Q5VU78_HUMAN,tr|F8W726|F8W726_HUMAN,tr|Q5VU81|Q5VU81_HUMAN,tr|Q5VU79|Q5VU79_HUMAN,tr|Q5VU80|Q5VU80_HUMAN,tr|Q5VU77|Q5VU77_HUMAN" 7 1861.8152 2.46 65349 13441 3 1861.817254 621.6124 Ubiquitin-associated protein 2-like OS=Homo sapiens OX=9606 GN=UBAP2L PE=1 SV=2 4.1 2514.3 - 665204 - - - 1.0801 - 3.611 0.518 - 499.7 1 2 0 0.002 16 0 0 0 5.43E+08 2.20E+08 - - - 7.6092 0.9732 221125_WJC_METTL3_EV_vs_WT_F05.13442.13442.3 0.242 Dec-52 K.VDQLGSDDIHNALK[136.11].Q "sp|Q14865|ARI5B_HUMAN,tr|A0A7P0TAD2|A0A7P0TAD2_HUMAN" 2 1531.7722 0.83 65350 13442 3 1531.781203 511.598 AT-rich interactive domain-containing protein 5B OS=Homo sapiens OX=9606 GN=ARID5B PE=1 SV=3 4.41 2514.4 - 607580 - - - 5.8866 - 2.044 0.264 - 164.8 1 2 0 0.009 14 0 0 0 3.44E+06 4.15E+06 - - - 3.3807 0.9975 221125_WJC_METTL3_EV_vs_WT_F05.13443.13443.3 0.155 Sep-36 R.IDISPSTFR[166.11]K[136.11].H "sp|Q9Y2W1|TR150_HUMAN,tr|A0A3B3ITZ9|A0A3B3ITZ9_HUMAN" 2 1180.6571 7.12 65351 13443 3 1180.656361 394.5596 Thyroid hormone receptor-associated protein 3 OS=Homo sapiens OX=9606 GN=THRAP3 PE=1 SV=2 8.75 2514.5 - 557595 - - - -0.62 - 1.773 0.222 - 95.1 1 2 0 -0.0007 10 0 0 0 3.37E+07 4.74E+06 - - - 2.6873 0.9997 221125_WJC_METTL3_EV_vs_WT_F05.13444.13444.3 0.0031 13/44 K.ATVMDVKPVDYR.E "sp|P27694|RFA1_HUMAN,tr|I3L4R8|I3L4R8_HUMAN" 2 1392.7071 0.38 65352 13444 3 1392.707847 465.243 Replication protein A 70 kDa DNA-binding subunit OS=Homo sapiens OX=9606 GN=RPA1 PE=1 SV=2 6 2514.6 - 487070 - - - 0.5105 - 2.042 0.341 - 201.6 1 2 0 0.0007 12 0 0 0 1.27E+07 3.36E+07 - - - 4.3205 0.9999 221125_WJC_METTL3_EV_vs_WT_F05.13445.13445.3 1.85E-12 18/56 M.PGHLQEGFGC[160.03]VVTNR.F sp|Q8NC51|PAIRB_HUMAN 1 1669.7995 -1 65353 13445 3 1669.805447 557.6071 Plasminogen activator inhibitor 1 RNA-binding protein OS=Homo sapiens OX=9606 GN=SERBP1 PE=1 SV=2 7.13 2514.7 - 439657 - - - 3.5771 - 3.255 0.603 - 416.7 1 2 0 0.006 15 0 0 0 0.00E+00 0.00E+00 - - - 8.3408 0.9984 221125_WJC_METTL3_EV_vs_WT_F05.13446.13446.3 0.00274 Nov-36 R.GYLDKLEPSK.L sp|P25705|ATPA_HUMAN 1 1148.6077 1.25 65354 13446 3 1148.60636 383.8765 "ATP synthase subunit alpha, mitochondrial OS=Homo sapiens OX=9606 GN=ATP5F1A PE=1 SV=1" 6.07 2514.9 - 401034 - - - -1.2015 - 1.808 0.353 - 152.6 1 2 1 -0.0014 10 0 0 0 1.04E+08 8.32E+07 - - - 4.2048 1 221125_WJC_METTL3_EV_vs_WT_F05.13447.13447.2 9.87E-05 14/26 K.SC[160.03]DPGLEDPC[160.03]GLNR[166.11].A "sp|Q9HAV4|XPO5_HUMAN,tr|H0Y3Q8|H0Y3Q8_HUMAN" 2 1598.6693 0.92 65355 13447 2 1598.67019 800.3419 Exportin-5 OS=Homo sapiens OX=9606 GN=XPO5 PE=1 SV=1 4.03 2515 - 379567 - - - 0.5811 - 2.562 0.633 - 463.3 1 2 0 0.0009 14 0 0 0 2.26E+06 2.46E+06 - - - 6.0769 1 221125_WJC_METTL3_EV_vs_WT_F05.13448.13448.3 2.85E-05 Nov-36 R.KDAEAWFNEK.S "sp|P13645|K1C10_HUMAN,sp|Q7Z3Y7|K1C28_HUMAN,tr|A0A1B0GVI3|A0A1B0GVI3_HUMAN" 3 1236.5775 16.12 65356 13448 3 1236.57748 413.1998 "Keratin, type I cytoskeletal 10 OS=Homo sapiens OX=9606 GN=KRT10 PE=1 SV=6" 4.68 2515.1 - 339390 - - - -0.0178 - 2.391 0.505 - 195.3 1 2 0 0 10 0 0 0 1.23E+07 7.61E+05 - - - 6.716 0.9993 221125_WJC_METTL3_EV_vs_WT_F05.13449.13449.3 0.132 Dec-56 K.QLQEELAEHQVPVEK[136.11].L "sp|Q9UPN3|MACF1_HUMAN,tr|H3BQK9|H3BQK9_HUMAN,tr|A0A7P0MQR8|A0A7P0MQR8_HUMAN,tr|H0Y390|H0Y390_HUMAN,tr|H3BPE1|H3BPE1_HUMAN,tr|A0A590UJG2|A0A590UJG2_HUMAN" 6 1783.9196 2.7 65357 13449 3 1783.919846 595.6471 "Microtubule-actin cross-linking factor 1, isoforms 1\2\3\5 OS=Homo sapiens OX=9606 GN=MACF1 PE=1 SV=4" 4.48 2515.3 - 251273 - - - 0.1502 - 2.052 0.279 - 174.4 1 2 0 0.0003 15 0 0 0 6.62E+06 2.45E+06 - - - 3.5262 0.9991 221125_WJC_METTL3_EV_vs_WT_F05.13454.13454.3 0.00582 Nov-40 K.K[136.11]LVESLPQEIK[136.11].A "sp|P52815|RM12_HUMAN,tr|B4DLN1|B4DLN1_HUMAN" 2 1298.7781 2 65360 13454 3 1298.777495 433.9333 "39S ribosomal protein L12, mitochondrial OS=Homo sapiens OX=9606 GN=MRPL12 PE=1 SV=2" 6.14 2515.9 - 3.45E+06 - - - -0.4296 - 2.202 0.233 - 238.7 1 2 0 -0.0006 11 0 0 0 7.28E+07 3.64E+07 - - - 3.38 1 221125_WJC_METTL3_EV_vs_WT_F05.13457.13457.2 1.06E-10 17/26 R.NALQQENHIIDGVK[136.11].V "sp|Q9GZT3|SLIRP_HUMAN,tr|H0YJW7|H0YJW7_HUMAN,tr|A0A087WUN7|A0A087WUN7_HUMAN,tr|G3V2S9|G3V2S9_HUMAN,tr|H0YJ40|H0YJ40_HUMAN,tr|G3V4X6|G3V4X6_HUMAN" 6 1585.8304 1.33 65363 13457 2 1585.829636 793.9225 "SRA stem-loop-interacting RNA-binding protein, mitochondrial OS=Homo sapiens OX=9606 GN=SLIRP PE=1 SV=1" 5.32 2516.1 - 2.52E+06 - - - -0.4622 - 3.494 0.652 - 1049.8 1 2 0 -0.0007 14 0 0 0 3.06E+08 2.29E+08 - - - 6.9959 1 221125_WJC_METTL3_EV_vs_WT_F05.13458.13458.2 2.81E-07 18/24 K.SVEEGK[136.11]IDGIIDK[136.11].T sp|Q96A49|SYAP1_HUMAN 1 1417.7635 1.3 65364 13458 2 1417.763081 709.889 Synapse-associated protein 1 OS=Homo sapiens OX=9606 GN=SYAP1 PE=1 SV=1 4.32 2516.2 - 2.28E+06 - - - -0.3132 - 3.279 0.543 - 938.6 1 2 1 -0.0004 13 0 0 0 5.62E+08 4.33E+08 - - - 6.0993 1 221125_WJC_METTL3_EV_vs_WT_F05.13459.13459.2 1.34E-07 16/24 K.SVEEGKIDGIIDK.T sp|Q96A49|SYAP1_HUMAN 1 1401.7351 1.3 65365 13459 2 1401.733213 701.8748 Synapse-associated protein 1 OS=Homo sapiens OX=9606 GN=SYAP1 PE=1 SV=1 4.32 2516.2 - 2.13E+06 - - - -1.364 - 3.082 0.541 - 670.8 1 2 1 -0.0019 13 0 0 0 5.62E+08 4.33E+08 - - - 5.9251 0.9999 221125_WJC_METTL3_EV_vs_WT_F05.13460.13460.3 0.000476 13/44 R.VC[160.03]EEIAIIPSKK.L "sp|P08708|RS17_HUMAN,tr|H0YN73|H0YN73_HUMAN,tr|H3BNC9|H3BNC9_HUMAN,tr|H0YN88|H0YN88_HUMAN,tr|A0A075B716|A0A075B716_HUMAN" 5 1385.7588 1.65 65366 13460 3 1385.755748 462.9269 40S ribosomal protein S17 OS=Homo sapiens OX=9606 GN=RPS17 PE=1 SV=2 6.11 2516.3 - 1.75E+06 - - - -2.2298 - 2.6 0.474 - 242.8 1 2 0 -0.0031 12 0 0 0 2.27E+09 1.38E+09 - - - 6.4723 0.9999 221125_WJC_METTL3_EV_vs_WT_F05.13461.13461.3 0.00278 Oct-48 R.TAFSDHQLNQLER.S sp|Q9NY43|BARH2_HUMAN 1 1557.7536 1.88 65367 13461 3 1557.753715 520.2585 BarH-like 2 homeobox protein OS=Homo sapiens OX=9606 GN=BARHL2 PE=1 SV=2 5.29 2516.4 - 1.18E+06 - - - 0.0937 - 2.107 0.431 - 120.7 1 2 0 0.0001 13 0 0 0 1.40E+07 7.46E+06 - - - 5.3658 0.8983 221125_WJC_METTL3_EV_vs_WT_F05.13463.13463.2 0.00127 17/20 V.EEGKIDGIIDK.T sp|Q96A49|SYAP1_HUMAN 1 1215.6347 1.43 65369 13463 2 1215.634976 608.8246 Synapse-associated protein 1 OS=Homo sapiens OX=9606 GN=SYAP1 PE=1 SV=1 4.32 2516.6 - 802500 - - - 0.241 - 2.522 0.382 - 853.1 1 1 1 0.0003 11 0 0 0 1.83E+08 1.28E+08 - - - 4.3648 0.9774 221125_WJC_METTL3_EV_vs_WT_F05.13464.13464.3 0.00072 Nov-48 Y.GFVHFETQEAAER[166.11].A "sp|P11940|PABP1_HUMAN,tr|A0A7I2YQE4|A0A7I2YQE4_HUMAN,tr|A0A7I2V649|A0A7I2V649_HUMAN,tr|H0YAR2|H0YAR2_HUMAN,tr|E7ERJ7|E7ERJ7_HUMAN,tr|A0A7I2YQ88|A0A7I2YQ88_HUMAN,tr|H0YBN4|H0YBN4_HUMAN,tr|E5RGH3|E5RGH3_HUMAN,tr|A0A087WTT1|A0A087WTT1_HUMAN,tr|A0A7I2YQ90|A0A7I2YQ90_HUMAN,tr|A0A7I2V4N4|A0A7I2V4N4_HUMAN,tr|E7EQV3|E7EQV3_HUMAN" 12 1529.7138 1.24 65370 13464 3 1529.71261 510.9119 Polyadenylate-binding protein 1 OS=Homo sapiens OX=9606 GN=PABPC1 PE=1 SV=2 4.75 2516.7 - 776121 - - - -0.7949 - 2.105 0.352 - 181.3 1 1 0 -0.0012 13 0 0 0 1.05E+07 8.54E+06 - - - 4.4822 1 221125_WJC_METTL3_EV_vs_WT_F05.13465.13465.2 1.26E-05 20-Oct K.GNEFEDYC[160.03]LK[136.11]R[166.11].E "sp|P26196|DDX6_HUMAN,tr|Q8IV96|Q8IV96_HUMAN" 2 1447.6521 1.17 65371 13465 2 1447.651957 724.8333 Probable ATP-dependent RNA helicase DDX6 OS=Homo sapiens OX=9606 GN=DDX6 PE=1 SV=2 4.68 2516.8 - 496445 - - - -0.0877 - 2.387 0.638 - 500.8 1 2 0 -0.0001 11 0 0 0 3.09E+06 2.65E+06 - - - 6.1069 0.9996 221125_WJC_METTL3_EV_vs_WT_F05.13466.13466.3 3.74E-07 15/44 R.SPSDLHISPLAK.K "sp|O95785|WIZ_HUMAN,tr|A0A669KBG4|A0A669KBG4_HUMAN,tr|A0A2R8YFV2|A0A2R8YFV2_HUMAN,tr|A0A669KAV7|A0A669KAV7_HUMAN,tr|M0QXA7|M0QXA7_HUMAN,tr|A0A669KBH9|A0A669KBH9_HUMAN,tr|B9EGQ5|B9EGQ5_HUMAN" 7 1263.6823 1.13 65372 13466 3 1263.677318 422.2347 Protein Wiz OS=Homo sapiens OX=9606 GN=WIZ PE=1 SV=2 6.46 2517 - 464269 - - - -3.944 - 2.924 0.389 - 409 1 2 0 -0.005 12 0 0 0 7.15E+06 6.31E+06 - - - 5.8497 0.9997 221125_WJC_METTL3_EV_vs_WT_F05.13467.13467.3 0.00974 Dec-44 R.HVFLTGPPGVGK[136.11].T "sp|Q9BSD7|NTPCR_HUMAN,tr|Q5TDF0|Q5TDF0_HUMAN" 2 1215.6855 1.68 65373 13467 3 1215.68592 406.2358 Cancer-related nucleoside-triphosphatase OS=Homo sapiens OX=9606 GN=NTPCR PE=1 SV=1 8.76 2517.1 - 451583 - - - 0.3101 - 2.007 0.332 - 147.1 1 2 0 0.0004 12 0 0 0 1.51E+07 9.02E+06 - - - 4.1724 1 221125_WJC_METTL3_EV_vs_WT_F05.13469.13469.3 0.000154 13/44 R.SPSDLHISPLAK[136.11].K "sp|O95785|WIZ_HUMAN,tr|A0A669KBG4|A0A669KBG4_HUMAN,tr|A0A2R8YFV2|A0A2R8YFV2_HUMAN,tr|A0A669KAV7|A0A669KAV7_HUMAN,tr|M0QXA7|M0QXA7_HUMAN,tr|A0A669KBH9|A0A669KBH9_HUMAN,tr|B9EGQ5|B9EGQ5_HUMAN" 7 1271.6965 1.58 65375 13469 3 1271.69463 424.9061 Protein Wiz OS=Homo sapiens OX=9606 GN=WIZ PE=1 SV=2 6.46 2517.4 - 356586 - - - -1.472 - 2.703 0.457 - 262.4 1 2 0 -0.0019 12 0 0 0 7.09E+06 4.48E+06 - - - 6.3908 0.9997 221125_WJC_METTL3_EV_vs_WT_F05.13473.13473.2 0.00312 18-Sep R.KDAEAWFNEK.S "sp|P13645|K1C10_HUMAN,sp|Q7Z3Y7|K1C28_HUMAN,tr|A0A1B0GVI3|A0A1B0GVI3_HUMAN" 3 1236.5775 999 65379 13473 2 1236.577387 619.296 "Keratin, type I cytoskeletal 10 OS=Homo sapiens OX=9606 GN=KRT10 PE=1 SV=6" 4.68 2517.9 - 185025 - - - -0.093 - 1.692 0.416 - 174.9 1 2 0 -0.0001 10 0 0 0 1.96E+06 0.00E+00 - - - 3.5815 0.9998 221125_WJC_METTL3_EV_vs_WT_F05.13475.13475.2 0.000703 28-Aug K.DLSEVSETTESTDVK.D sp|P41227|NAA10_HUMAN 1 1638.7472 1.53 65380 13475 2 1638.745509 820.3809 N-alpha-acetyltransferase 10 OS=Homo sapiens OX=9606 GN=NAA10 PE=1 SV=1 3.83 2518.1 - 258035 - - - -1.0355 - 1.81 0.491 - 134.7 1 2 0 -0.0017 15 0 0 0 3.32E+06 2.17E+06 - - - 4.1257 1 221125_WJC_METTL3_EV_vs_WT_F05.13477.13477.3 1.18E-09 17/56 M.PGHLQEGFGC[160.03]VVTNR[166.11].F sp|Q8NC51|PAIRB_HUMAN 1 1679.8077 0.76 65382 13477 3 1679.805789 560.9432 Plasminogen activator inhibitor 1 RNA-binding protein OS=Homo sapiens OX=9606 GN=SERBP1 PE=1 SV=2 7.13 2518.3 - 1.22E+07 - - - -1.1638 - 3.188 0.616 - 373.2 1 2 0 -0.002 15 0 0 0 4.76E+08 6.28E+08 - - - 8.4325 1 221125_WJC_METTL3_EV_vs_WT_F05.13478.13478.2 5.74E-11 19/26 R.NALQQENHIIDGVK.V "sp|Q9GZT3|SLIRP_HUMAN,tr|H0YJW7|H0YJW7_HUMAN,tr|A0A087WUN7|A0A087WUN7_HUMAN,tr|G3V2S9|G3V2S9_HUMAN,tr|H0YJ40|H0YJ40_HUMAN,tr|G3V4X6|G3V4X6_HUMAN" 6 1577.8162 1.33 65383 13478 2 1577.814632 789.9154 "SRA stem-loop-interacting RNA-binding protein, mitochondrial OS=Homo sapiens OX=9606 GN=SLIRP PE=1 SV=1" 5.32 2518.3 - 7.32E+06 - - - -0.9741 - 3.715 0.66 - 1267.9 1 2 0 -0.0015 14 0 0 0 3.06E+08 2.29E+08 - - - 7.2086 0.9279 221125_WJC_METTL3_EV_vs_WT_F05.13479.13479.2 0.00194 14/20 V.EEGK[136.11]IDGIIDK[136.11].T sp|Q96A49|SYAP1_HUMAN 1 1231.6631 1.43 65384 13479 2 1231.662201 616.8388 Synapse-associated protein 1 OS=Homo sapiens OX=9606 GN=SYAP1 PE=1 SV=1 4.32 2518.4 - 2.26E+06 - - - -0.7161 - 2.607 0.468 - 568.4 1 1 1 -0.0009 11 0 0 0 1.83E+08 1.28E+08 - - - 5.0895 1 221125_WJC_METTL3_EV_vs_WT_F05.13483.13483.2 4.07E-11 16/30 R.LAQMISDHNDADFEEK.V "sp|Q14157|UBP2L_HUMAN,tr|Q5VU78|Q5VU78_HUMAN,tr|F8W726|F8W726_HUMAN,tr|Q5VU81|Q5VU81_HUMAN,tr|Q5VU79|Q5VU79_HUMAN,tr|Q5VU80|Q5VU80_HUMAN,tr|Q5VU77|Q5VU77_HUMAN" 7 1861.8152 2.95 65388 13483 2 1861.817114 931.9149 Ubiquitin-associated protein 2-like OS=Homo sapiens OX=9606 GN=UBAP2L PE=1 SV=2 4.1 2518.7 - 856892 - - - 1.0049 - 3.689 0.721 - 690.7 1 2 0 0.0019 16 0 0 0 2.65E+07 8.97E+06 - - - 7.575 0.9998 221125_WJC_METTL3_EV_vs_WT_F05.13484.13484.3 0.000113 14/52 K.GSLSSLK[136.11]EEGGLYR[166.11].D "sp|Q9BUK6|MSTO1_HUMAN,tr|A0A3B3IUD2|A0A3B3IUD2_HUMAN" 2 1512.7903 2.23 65389 13484 3 1512.789566 505.2707 Protein misato homolog 1 OS=Homo sapiens OX=9606 GN=MSTO1 PE=1 SV=1 6.14 2518.8 - 772526 - - - -0.4799 - 2.526 0.478 - 242.2 1 2 1 -0.0007 14 0 0 0 2.61E+07 1.17E+07 - - - 6.3316 0.9998 221125_WJC_METTL3_EV_vs_WT_F05.13485.13485.2 5.24E-07 13/28 M.PGHLQEGFGC[160.03]VVTNR.F sp|Q8NC51|PAIRB_HUMAN 1 1669.7995 0.93 65390 13485 2 1669.797455 835.907 Plasminogen activator inhibitor 1 RNA-binding protein OS=Homo sapiens OX=9606 GN=SERBP1 PE=1 SV=2 7.13 2519 - 515222 - - - -1.2091 - 2.561 0.438 - 484.8 1 2 0 -0.002 15 0 0 0 2.79E+07 2.99E+07 - - - 4.5874 0.9997 221125_WJC_METTL3_EV_vs_WT_F05.13486.13486.3 0.000114 13/36 K.ESVEDKLELR.R "sp|Q6I9Y2|THOC7_HUMAN,tr|A0A5S6STF9|A0A5S6STF9_HUMAN" 2 1216.6299 1.74 65391 13486 3 1216.628748 406.5506 THO complex subunit 7 homolog OS=Homo sapiens OX=9606 GN=THOC7 PE=1 SV=3 4.41 2519.1 - 479132 - - - -0.9732 - 2.183 0.419 - 305.1 1 2 1 -0.0012 10 0 0 0 1.46E+07 8.39E+06 - - - 5.4911 0.9995 221125_WJC_METTL3_EV_vs_WT_F05.13491.13491.3 6.51E-07 Dec-44 K.NLDDTIDDEKLR.K "sp|Q13310|PABP4_HUMAN,sp|P0CB38|PAB4L_HUMAN,tr|A0A7I2V5W9|A0A7I2V5W9_HUMAN,tr|H0YEU6|H0YEU6_HUMAN,tr|B1ANR0|B1ANR0_HUMAN,tr|A0A7I2V4L7|A0A7I2V4L7_HUMAN,tr|A0A7I2V598|A0A7I2V598_HUMAN,tr|H0Y5F5|H0Y5F5_HUMAN" 8 1445.6998 1.79 65394 13491 3 1445.695076 482.9072 Polyadenylate-binding protein 4 OS=Homo sapiens OX=9606 GN=PABPC4 PE=1 SV=1 4.04 2519.7 - 6.33E+06 - - - -3.269 - 2.786 0.479 - 209.9 1 2 1 -0.0047 12 0 0 0 1.37E+08 7.67E+07 - - - 6.7191 0.9941 221125_WJC_METTL3_EV_vs_WT_F05.13492.13492.3 9.47E-07 14/52 S.AVPELATDPELEK[136.11]K[136.11].L "sp|Q86U44|MTA70_HUMAN,tr|B4E349|B4E349_HUMAN,tr|F5H6D8|F5H6D8_HUMAN,tr|H0YFV6|H0YFV6_HUMAN,tr|B4DTN4|B4DTN4_HUMAN" 5 1554.8476 0.02 65395 13492 3 1554.843391 519.2898 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 4.41 2519.8 - 5.70E+06 - - - -2.6999 - 2.802 0.527 - 266.2 1 1 0 -0.0042 14 0 0 0 1.77E+06 9.79E+07 - - - 7.1525 1 221125_WJC_METTL3_EV_vs_WT_F05.13494.13494.2 7.73E-09 13/30 R.LAQMISDHNDADFEEK[136.11].V "sp|Q14157|UBP2L_HUMAN,tr|Q5VU78|Q5VU78_HUMAN,tr|F8W726|F8W726_HUMAN,tr|Q5VU81|Q5VU81_HUMAN,tr|Q5VU79|Q5VU79_HUMAN,tr|Q5VU80|Q5VU80_HUMAN,tr|Q5VU77|Q5VU77_HUMAN" 7 1869.8294 2.95 65397 13494 2 1869.817609 935.922 Ubiquitin-associated protein 2-like OS=Homo sapiens OX=9606 GN=UBAP2L PE=1 SV=2 4.1 2520 - 505889 - - - -6.3289 - 3.098 0.683 - 447.7 1 2 0 -0.0118 16 0 0 0 2.65E+07 8.97E+06 - - - 6.8619 0.9999 221125_WJC_METTL3_EV_vs_WT_F05.13497.13497.3 0.00012 14/48 K.QGLELAADC[160.03]HLSR[166.11].L "sp|P55196|AFAD_HUMAN,tr|J3KN01|J3KN01_HUMAN,tr|A0A804HJ20|A0A804HJ20_HUMAN,tr|Q5TIG5|Q5TIG5_HUMAN,tr|A8MQ02|A8MQ02_HUMAN" 5 1478.7175 0.16 65400 13497 3 1478.712603 493.9131 Afadin OS=Homo sapiens OX=9606 GN=AFDN PE=1 SV=3 5.32 2520.4 - 394114 - - - -3.3333 - 3.154 0.501 - 362.8 1 2 0 -0.0049 13 0 0 0 3.98E+05 2.46E+06 - - - 7.2387 1 221125_WJC_METTL3_EV_vs_WT_F05.13500.13500.3 2.46E-05 17/64 K.MAPVPLDDSNRPASLTK.D "sp|Q9NYF8|BCLF1_HUMAN,tr|E9PKI6|E9PKI6_HUMAN,tr|A0A1W2PQ43|A0A1W2PQ43_HUMAN,tr|E9PK91|E9PK91_HUMAN,tr|E9PJA7|E9PJA7_HUMAN,tr|E9PK09|E9PK09_HUMAN,tr|E9PQN2|E9PQN2_HUMAN" 7 1810.9247 2.42 65401 13500 3 1810.921686 604.6489 Bcl-2-associated transcription factor 1 OS=Homo sapiens OX=9606 GN=BCLAF1 PE=1 SV=2 5.71 2520.8 - 4.26E+06 - - - -1.6831 - 2.927 0.524 - 245.9 1 2 0 -0.003 17 0 0 0 1.21E+10 4.98E+09 - - - 7.0944 0.99 221125_WJC_METTL3_EV_vs_WT_F05.13502.13502.2 1.34E-06 16/22 R.VC[160.03]EEIAIIPSKK.L "sp|P08708|RS17_HUMAN,tr|H0YN73|H0YN73_HUMAN,tr|H3BNC9|H3BNC9_HUMAN,tr|H0YN88|H0YN88_HUMAN,tr|A0A075B716|A0A075B716_HUMAN" 5 1385.7588 2.1 65403 13502 2 1385.754019 693.8867 40S ribosomal protein S17 OS=Homo sapiens OX=9606 GN=RPS17 PE=1 SV=2 6.11 2521 - 1.27E+06 - - - -3.4775 - 2.599 0.058 - 941.6 1 2 0 -0.0048 12 0 0 0 1.88E+08 8.92E+07 - - - 1.981 0.9888 221125_WJC_METTL3_EV_vs_WT_F05.13504.13504.3 9.07E-05 13/36 K.ESVEDK[136.11]LELR[166.11].R "sp|Q6I9Y2|THOC7_HUMAN,tr|A0A5S6STF9|A0A5S6STF9_HUMAN" 2 1234.6524 2.16 65405 13504 3 1234.645848 412.5581 THO complex subunit 7 homolog OS=Homo sapiens OX=9606 GN=THOC7 PE=1 SV=3 4.41 2521.2 - 770186 - - - -5.3084 - 2.345 0.356 - 310.6 1 2 1 -0.0066 10 0 0 0 1.83E+07 8.46E+06 - - - 4.9963 0.9941 221125_WJC_METTL3_EV_vs_WT_F05.13505.13505.3 0.000168 14/56 K.QALQGER[166.11]EGLEETLR[166.11].N sp|P07196|NFL_HUMAN 1 1747.8968 0.81 65406 13505 3 1747.891398 583.6395 Neurofilament light polypeptide OS=Homo sapiens OX=9606 GN=NEFL PE=1 SV=3 4.49 2521.4 - 764957 - - - -3.0711 - 2.463 0.293 - 288.3 1 2 1 -0.0054 15 0 0 0 1.02E+07 1.25E+07 - - - 4.1572 0.9398 221125_WJC_METTL3_EV_vs_WT_F05.13506.13506.2 2.21E-05 15/22 S.VEEGKIDGIIDK.T sp|Q96A49|SYAP1_HUMAN 1 1314.7031 1.49 65407 13506 2 1314.702571 658.3588 Synapse-associated protein 1 OS=Homo sapiens OX=9606 GN=SYAP1 PE=1 SV=1 4.32 2521.5 - 572428 - - - -0.4001 - 3.232 0.438 - 903.9 1 1 1 -0.0005 12 0 0 0 1.18E+07 7.88E+06 - - - 5.3625 0.985 221125_WJC_METTL3_EV_vs_WT_F05.13507.13507.2 4.88E-05 18-Sep Q.QENHIIDGVK[136.11].V "sp|Q9GZT3|SLIRP_HUMAN,tr|H0YJW7|H0YJW7_HUMAN,tr|A0A087WUN7|A0A087WUN7_HUMAN,tr|G3V2S9|G3V2S9_HUMAN,tr|H0YJ40|H0YJ40_HUMAN,tr|G3V4X6|G3V4X6_HUMAN" 6 1159.6077 1.83 65408 13507 2 1159.608554 580.8111 "SRA stem-loop-interacting RNA-binding protein, mitochondrial OS=Homo sapiens OX=9606 GN=SLIRP PE=1 SV=1" 5.32 2521.7 - 344515 - - - 0.7477 - 1.749 0.46 - 298.1 1 1 0 0.0009 10 0 0 0 2.16E+06 1.18E+06 - - - 3.9987 1 221125_WJC_METTL3_EV_vs_WT_F05.13512.13512.2 1.24E-09 19/28 M.PGHLQEGFGC[160.03]VVTNR[166.11].F sp|Q8NC51|PAIRB_HUMAN 1 1679.8077 0.98 65411 13512 2 1679.798974 840.9111 Plasminogen activator inhibitor 1 RNA-binding protein OS=Homo sapiens OX=9606 GN=SERBP1 PE=1 SV=2 7.13 2522.3 - 1.21E+06 - - - -5.2208 - 3.39 0.631 - 1046.7 1 2 0 -0.0088 15 0 0 0 2.93E+07 3.00E+07 - - - 6.7003 0.9632 221125_WJC_METTL3_EV_vs_WT_F05.13513.13513.2 0.000148 18-Sep L.NVELDPEIQK.V "sp|Q86Y46|K2C73_HUMAN,sp|Q7RTS7|K2C74_HUMAN,sp|Q3SY84|K2C71_HUMAN,sp|P04264|K2C1_HUMAN,tr|F8W1S1|F8W1S1_HUMAN" 5 1183.6085 999 65412 13513 2 1183.607817 592.8115 "Keratin, type II cytoskeletal 73 OS=Homo sapiens OX=9606 GN=KRT73 PE=1 SV=1" 4.14 2522.4 - 992424 - - - -0.55 - 1.784 0.293 - 234 1 1 0 -0.0007 10 0 0 0 2.02E+07 0.00E+00 - - - 2.8207 1 221125_WJC_METTL3_EV_vs_WT_F05.13518.13518.3 1.73E-09 13/60 R.LAQMISDHNDADFEEK[136.11].V "sp|Q14157|UBP2L_HUMAN,tr|Q5VU78|Q5VU78_HUMAN,tr|F8W726|F8W726_HUMAN,tr|Q5VU81|Q5VU81_HUMAN,tr|Q5VU79|Q5VU79_HUMAN,tr|Q5VU80|Q5VU80_HUMAN,tr|Q5VU77|Q5VU77_HUMAN" 7 1869.8294 2.63 65415 13518 3 1869.824948 624.2838 Ubiquitin-associated protein 2-like OS=Homo sapiens OX=9606 GN=UBAP2L PE=1 SV=2 4.1 2523 - 1.30E+07 - - - -2.404 - 3.061 0.617 - 220.3 1 2 0 -0.0045 16 0 0 0 5.99E+08 2.28E+08 - - - 8.2882 0.9808 221125_WJC_METTL3_EV_vs_WT_F05.13519.13519.2 2.31E-06 13/20 L.QQENHIIDGVK.V "sp|Q9GZT3|SLIRP_HUMAN,tr|H0YJW7|H0YJW7_HUMAN,tr|A0A087WUN7|A0A087WUN7_HUMAN,tr|G3V2S9|G3V2S9_HUMAN,tr|H0YJ40|H0YJ40_HUMAN,tr|G3V4X6|G3V4X6_HUMAN" 6 1279.6521 1.44 65416 13519 2 1279.654525 640.8333 "SRA stem-loop-interacting RNA-binding protein, mitochondrial OS=Homo sapiens OX=9606 GN=SLIRP PE=1 SV=1" 5.32 2523.1 - 805140 - - - 1.9232 - 2.213 0.452 - 582.6 1 1 0 0.0025 11 0 0 0 1.55E+07 1.08E+07 - - - 4.5276 0.9988 221125_WJC_METTL3_EV_vs_WT_F05.13520.13520.2 1.34E-05 14/24 K.SVEEGK[136.11]IDGIIDK.T sp|Q96A49|SYAP1_HUMAN 1 1409.7493 - 65417 13520 2 1409.748362 705.8819 Synapse-associated protein 1 OS=Homo sapiens OX=9606 GN=SYAP1 PE=1 SV=1 4.32 2523.2 - 740475 - - - -0.6831 - 2.554 0.511 - 383.9 1 2 1 -0.001 13 0 0 0 - - - - - 5.2215 1 221125_WJC_METTL3_EV_vs_WT_F05.13521.13521.2 2.26E-06 13/22 K.NLDDTIDDEKLR.K "sp|Q13310|PABP4_HUMAN,sp|P0CB38|PAB4L_HUMAN,tr|A0A7I2V5W9|A0A7I2V5W9_HUMAN,tr|H0YEU6|H0YEU6_HUMAN,tr|B1ANR0|B1ANR0_HUMAN,tr|A0A7I2V4L7|A0A7I2V4L7_HUMAN,tr|A0A7I2V598|A0A7I2V598_HUMAN,tr|H0Y5F5|H0Y5F5_HUMAN" 8 1445.6998 999 65418 13521 2 1445.699205 723.8572 Polyadenylate-binding protein 4 OS=Homo sapiens OX=9606 GN=PABPC4 PE=1 SV=1 4.04 2523.4 - 667123 - - - -0.4129 - 2.817 0.54 - 513.5 1 2 1 -0.0006 12 0 0 0 1.14E+07 0.00E+00 - - - 5.7543 0.9999 221125_WJC_METTL3_EV_vs_WT_F05.13522.13522.2 1.16E-06 Sep-32 K.MAPVPLDDSNRPASLTK.D "sp|Q9NYF8|BCLF1_HUMAN,tr|E9PKI6|E9PKI6_HUMAN,tr|A0A1W2PQ43|A0A1W2PQ43_HUMAN,tr|E9PK91|E9PK91_HUMAN,tr|E9PJA7|E9PJA7_HUMAN,tr|E9PK09|E9PK09_HUMAN,tr|E9PQN2|E9PQN2_HUMAN" 7 1810.9247 2.42 65419 13522 2 1810.923017 906.4696 Bcl-2-associated transcription factor 1 OS=Homo sapiens OX=9606 GN=BCLAF1 PE=1 SV=2 5.71 2523.5 - 470107 - - - -0.9481 - 2.279 0.546 - 106.3 1 2 0 -0.0017 17 0 0 0 3.88E+08 1.61E+08 - - - 5.0984 0.9967 221125_WJC_METTL3_EV_vs_WT_F05.13527.13527.3 0.00206 Dec-40 R.EKQPPIDNIIR.A "sp|P52292|IMA1_HUMAN,tr|J3QLL0|J3QLL0_HUMAN,tr|J3KS65|J3KS65_HUMAN,tr|A0A7I2V3Z3|A0A7I2V3Z3_HUMAN,tr|A0A7I2YQE1|A0A7I2YQE1_HUMAN,tr|A0A7I2V487|A0A7I2V487_HUMAN,tr|A0A7I2V351|A0A7I2V351_HUMAN" 7 1321.7354 1.32 65422 13527 3 1321.731698 441.5857 Importin subunit alpha-1 OS=Homo sapiens OX=9606 GN=KPNA2 PE=1 SV=1 6.17 2524.2 - 1.12E+06 - - - -2.8009 - 2.512 0.298 - 296.6 1 2 1 -0.0037 11 0 0 0 2.08E+08 1.57E+08 - - - 4.478 0.9999 221125_WJC_METTL3_EV_vs_WT_F05.13528.13528.3 6.01E-08 Dec-52 R.STAYEDYYYHPPPR.M "sp|O43390|HNRPR_HUMAN,tr|B4DT28|B4DT28_HUMAN,tr|A0A6Q8PH35|A0A6Q8PH35_HUMAN,tr|A0A286YEZ8|A0A286YEZ8_HUMAN" 4 1757.7686 1.36 65423 13528 3 1757.763501 586.9301 Heterogeneous nuclear ribonucleoprotein R OS=Homo sapiens OX=9606 GN=HNRNPR PE=1 SV=1 5.3 2524.3 - 444621 - - - -2.8724 - 2.125 0.594 - 164.5 1 2 0 -0.005 14 0 0 0 1.65E+08 1.22E+08 - - - 7.1643 0.9972 221125_WJC_METTL3_EV_vs_WT_F05.13531.13531.3 0.00109 Nov-40 R.EK[136.11]QPPIDNIIR[166.11].A "sp|P52292|IMA1_HUMAN,tr|J3QLL0|J3QLL0_HUMAN,tr|J3KS65|J3KS65_HUMAN,tr|A0A7I2V3Z3|A0A7I2V3Z3_HUMAN,tr|A0A7I2YQE1|A0A7I2YQE1_HUMAN,tr|A0A7I2V487|A0A7I2V487_HUMAN,tr|A0A7I2V351|A0A7I2V351_HUMAN" 7 1339.7579 1.32 65424 13531 3 1339.754008 447.5932 Importin subunit alpha-1 OS=Homo sapiens OX=9606 GN=KPNA2 PE=1 SV=1 6.17 2524.7 - 1.66E+06 - - - -2.8826 - 2.154 0.354 - 249.8 1 2 1 -0.0039 11 0 0 0 2.05E+08 1.55E+08 - - - 4.6655 1 221125_WJC_METTL3_EV_vs_WT_F05.13534.13534.2 3.69E-08 13/32 K.MAPVPLDDSNR[166.11]PASLTK[136.11].D "sp|Q9NYF8|BCLF1_HUMAN,tr|E9PKI6|E9PKI6_HUMAN,tr|A0A1W2PQ43|A0A1W2PQ43_HUMAN,tr|E9PK91|E9PK91_HUMAN,tr|E9PJA7|E9PJA7_HUMAN,tr|E9PK09|E9PK09_HUMAN,tr|E9PQN2|E9PQN2_HUMAN" 7 1828.9472 2.42 65427 13534 2 1828.945646 915.4809 Bcl-2-associated transcription factor 1 OS=Homo sapiens OX=9606 GN=BCLAF1 PE=1 SV=2 5.71 2525 - 772199 - - - -0.8519 - 2.622 0.6 - 306.6 1 2 0 -0.0016 17 0 0 0 3.88E+08 1.61E+08 - - - 5.842 1 221125_WJC_METTL3_EV_vs_WT_F05.13545.13545.2 1.12E-07 15/20 K.HEAMITDLEER.L sp|P35579|MYH9_HUMAN 1 1342.6187 1.4 65434 13545 2 1342.614999 672.3166 Myosin-9 OS=Homo sapiens OX=9606 GN=MYH9 PE=1 SV=4 4.4 2526.4 - 610462 - - - -2.7677 - 2.697 0.618 - 795.4 1 2 0 -0.0037 11 0 0 0 1.50E+07 1.07E+07 - - - 6.2884 0.9995 221125_WJC_METTL3_EV_vs_WT_F05.13546.13546.2 4.48E-07 14/24 K.QFLEC[160.03]AQNQGDIK.L "sp|Q5T1J5|CHCH9_HUMAN,sp|Q9Y6H1|CHCH2_HUMAN" 2 1549.7195 7.77 65435 13546 2 1549.714726 775.867 "Putative coiled-coil-helix-coiled-coil-helix domain-containing protein CHCHD2P9, mitochondrial OS=Homo sapiens OX=9606 GN=CHCHD2P9 PE=5 SV=1" 4.37 2526.5 - 526960 - - - -3.0754 - 2.78 0.49 - 828.8 1 2 0 -0.0048 13 0 0 0 8.95E+06 1.15E+06 - - - 5.2828 1 221125_WJC_METTL3_EV_vs_WT_F05.13547.13547.2 6.72E-14 19/32 K.LGAPAAGGEEEWGQQQR[166.11].Q sp|O94992|HEXI1_HUMAN 1 1792.8368 0.68 65436 13547 2 1792.82899 897.4257 Protein HEXIM1 OS=Homo sapiens OX=9606 GN=HEXIM1 PE=1 SV=1 4.25 2526.6 - 436757 - - - -4.3534 - 3.953 0.679 - 1195.8 1 2 0 -0.0078 17 0 0 0 4.87E+06 7.21E+06 - - - 7.4329 1 221125_WJC_METTL3_EV_vs_WT_F05.13548.13548.2 3.45E-05 19/24 V.PLDDSNR[166.11]PASLTK[136.11].D "sp|Q9NYF8|BCLF1_HUMAN,tr|E9PKI6|E9PKI6_HUMAN,tr|A0A1W2PQ43|A0A1W2PQ43_HUMAN,tr|E9PK91|E9PK91_HUMAN,tr|E9PJA7|E9PJA7_HUMAN,tr|E9PK09|E9PK09_HUMAN,tr|E9PQN2|E9PQN2_HUMAN" 7 1430.7484 11.77 65437 13548 2 1430.743475 716.3815 Bcl-2-associated transcription factor 1 OS=Homo sapiens OX=9606 GN=BCLAF1 PE=1 SV=2 6.38 2526.8 - 421325 - - - -3.4611 - 3.386 0.566 - 1165.4 1 1 0 -0.005 13 0 0 0 6.02E+07 5.12E+06 - - - 6.3502 0.9997 221125_WJC_METTL3_EV_vs_WT_F05.13549.13549.3 0.00408 Aug-32 K.KNFEWVAER.V "sp|P22234|PUR6_HUMAN,tr|D6RF62|D6RF62_HUMAN,tr|E9PBS1|E9PBS1_HUMAN" 3 1177.588 0.51 65438 13549 3 1177.585255 393.5366 Multifunctional protein ADE2 OS=Homo sapiens OX=9606 GN=PAICS PE=1 SV=3 6.14 2526.9 - 303815 - - - -2.337 - 1.914 0.409 - 135.6 1 2 0 -0.0028 9 0 0 0 4.23E+06 8.27E+06 - - - 5.0557 1 221125_WJC_METTL3_EV_vs_WT_F05.13552.13552.3 1.43E-06 15/52 R.GSITHGTPADVLYK.G "sp|Q9Y618|NCOR2_HUMAN,tr|C9JQE8|C9JQE8_HUMAN,tr|C9J7T7|C9J7T7_HUMAN,tr|C9JE98|C9JE98_HUMAN,tr|C9J0Q5|C9J0Q5_HUMAN,tr|A0A384DVL6|A0A384DVL6_HUMAN" 6 1457.7514 3.23 65439 13552 3 1457.749104 486.9244 Nuclear receptor corepressor 2 OS=Homo sapiens OX=9606 GN=NCOR2 PE=1 SV=3 6.74 2527.3 - 1.38E+06 - - - -1.6052 - 2.944 0.469 - 261.9 1 2 0 -0.0023 14 0 0 0 3.32E+07 1.03E+07 - - - 6.6378 0.9998 221125_WJC_METTL3_EV_vs_WT_F05.13553.13553.2 0.000262 14/14 R.KDLQNFLK.K sp|P06702|S10A9_HUMAN 1 1004.5655 1269.6 65440 13553 2 1004.564065 503.29 Protein S100-A9 OS=Homo sapiens OX=9606 GN=S100A9 PE=1 SV=1 8.59 2527.4 - 1.45E+06 - - - -1.4096 - 2.733 0.335 - 684.9 1 2 0 -0.0014 8 0 0 0 9.73E+07 7.67E+04 - - - 4.5471 0.9983 221125_WJC_METTL3_EV_vs_WT_F05.13558.13558.3 0.0142 Nov-32 K.K[136.11]NFEWVAER[166.11].V "sp|P22234|PUR6_HUMAN,tr|D6RF62|D6RF62_HUMAN,tr|E9PBS1|E9PBS1_HUMAN" 3 1195.6105 0.52 65445 13558 3 1195.607278 399.5441 Multifunctional protein ADE2 OS=Homo sapiens OX=9606 GN=PAICS PE=1 SV=3 6.14 2528 - 440502 - - - -2.6756 - 1.929 0.287 - 252.6 1 2 0 -0.0032 9 0 0 0 4.23E+06 8.19E+06 - - - 3.7189 0.9999 221125_WJC_METTL3_EV_vs_WT_F05.13561.13561.3 1.95E-05 15/64 K.MAPVPLDDSNR[166.11]PASLTK[136.11].D "sp|Q9NYF8|BCLF1_HUMAN,tr|E9PKI6|E9PKI6_HUMAN,tr|A0A1W2PQ43|A0A1W2PQ43_HUMAN,tr|E9PK91|E9PK91_HUMAN,tr|E9PJA7|E9PJA7_HUMAN,tr|E9PK09|E9PK09_HUMAN,tr|E9PQN2|E9PQN2_HUMAN" 7 1828.9472 2.42 65447 13561 3 1828.942508 610.6563 Bcl-2-associated transcription factor 1 OS=Homo sapiens OX=9606 GN=BCLAF1 PE=1 SV=2 5.71 2528.4 - 1.24E+08 - - - -2.5676 - 2.347 0.482 - 199 1 2 0 -0.0047 17 0 0 0 1.21E+10 4.98E+09 - - - 6.0678 0.9997 221125_WJC_METTL3_EV_vs_WT_F05.13562.13562.3 4.46E-05 15/48 K.ALKEEIGNVQLEK.A "sp|Q86UP2|KTN1_HUMAN,tr|G3V4Y7|G3V4Y7_HUMAN,tr|G3V5G2|G3V5G2_HUMAN,tr|H0YJZ8|H0YJZ8_HUMAN" 4 1469.809 1.81 65448 13562 3 1469.806269 490.9436 Kinectin OS=Homo sapiens OX=9606 GN=KTN1 PE=1 SV=1 4.79 2528.4 - 3.60E+06 - - - -1.8302 - 2.625 0.464 - 378.4 1 2 1 -0.0027 13 0 0 0 5.29E+07 2.92E+07 - - - 6.329 0.9999 221125_WJC_METTL3_EV_vs_WT_F05.13563.13563.3 3.49E-06 Dec-44 R.VC[160.03]EEIAIIPSK[136.11]K[136.11].L "sp|P08708|RS17_HUMAN,tr|H0YN73|H0YN73_HUMAN,tr|H3BNC9|H3BNC9_HUMAN,tr|H0YN88|H0YN88_HUMAN,tr|A0A075B716|A0A075B716_HUMAN" 5 1401.7872 1.65 65449 13563 3 1401.784037 468.2697 40S ribosomal protein S17 OS=Homo sapiens OX=9606 GN=RPS17 PE=1 SV=2 6.11 2528.5 - 6.71E+07 - - - -2.2835 - 2.172 0.496 - 172.2 1 2 0 -0.0032 12 0 0 0 2.27E+09 1.38E+09 - - - 6.219 0.9997 221125_WJC_METTL3_EV_vs_WT_F05.13564.13564.3 0.000319 14/48 K.ALK[136.11]EEIGNVQLEK[136.11].A "sp|Q86UP2|KTN1_HUMAN,tr|G3V4Y7|G3V4Y7_HUMAN,tr|G3V5G2|G3V5G2_HUMAN,tr|H0YJZ8|H0YJZ8_HUMAN" 4 1485.8374 1.81 65450 13564 3 1485.833587 496.2864 Kinectin OS=Homo sapiens OX=9606 GN=KTN1 PE=1 SV=1 4.79 2528.6 - 1.73E+06 - - - -2.5386 - 2.879 0.468 - 290.7 1 2 1 -0.0038 13 0 0 0 5.29E+07 2.92E+07 - - - 6.6237 0.9981 221125_WJC_METTL3_EV_vs_WT_F05.13566.13566.3 3.23E-05 22/56 A.PVPLDDSNR[166.11]PASLTK[136.11].D "sp|Q9NYF8|BCLF1_HUMAN,tr|E9PKI6|E9PKI6_HUMAN,tr|A0A1W2PQ43|A0A1W2PQ43_HUMAN,tr|E9PK91|E9PK91_HUMAN,tr|E9PJA7|E9PJA7_HUMAN,tr|E9PK09|E9PK09_HUMAN,tr|E9PQN2|E9PQN2_HUMAN" 7 1626.8696 3.24 65452 13566 3 1626.868611 543.2971 Bcl-2-associated transcription factor 1 OS=Homo sapiens OX=9606 GN=BCLAF1 PE=1 SV=2 6.38 2528.8 - 1.03E+06 - - - -0.611 - 3.119 0.514 - 383.1 1 1 0 -0.001 15 0 0 0 1.03E+08 3.20E+07 - - - 7.2385 0.9872 221125_WJC_METTL3_EV_vs_WT_F05.13569.13569.2 0.00263 20-Dec R.EKQPPIDNIIR.A "sp|P52292|IMA1_HUMAN,tr|J3QLL0|J3QLL0_HUMAN,tr|J3KS65|J3KS65_HUMAN,tr|A0A7I2V3Z3|A0A7I2V3Z3_HUMAN,tr|A0A7I2YQE1|A0A7I2YQE1_HUMAN,tr|A0A7I2V487|A0A7I2V487_HUMAN,tr|A0A7I2V351|A0A7I2V351_HUMAN" 7 1321.7354 1.32 65455 13569 2 1321.737386 661.875 Importin subunit alpha-1 OS=Homo sapiens OX=9606 GN=KPNA2 PE=1 SV=1 6.17 2529.2 - 812325 - - - 1.5026 - 1.827 0.279 - 475.6 1 2 1 0.002 11 0 0 0 2.19E+07 1.65E+07 - - - 2.7314 1 221125_WJC_METTL3_EV_vs_WT_F05.13573.13573.2 4.82E-07 13/22 R.VC[160.03]EEIAIIPSK[136.11]K[136.11].L "sp|P08708|RS17_HUMAN,tr|H0YN73|H0YN73_HUMAN,tr|H3BNC9|H3BNC9_HUMAN,tr|H0YN88|H0YN88_HUMAN,tr|A0A075B716|A0A075B716_HUMAN" 5 1401.7872 2.1 65457 13573 2 1401.785909 701.9009 40S ribosomal protein S17 OS=Homo sapiens OX=9606 GN=RPS17 PE=1 SV=2 6.11 2529.7 - 4.82E+06 - - - -0.9481 - 2.459 0.628 - 574.2 1 2 0 -0.0013 12 0 0 0 1.87E+08 8.92E+07 - - - 6.0464 0.954 221125_WJC_METTL3_EV_vs_WT_F05.13574.13574.2 1.62E-05 15/28 A.PVPLDDSNRPASLTK.D "sp|Q9NYF8|BCLF1_HUMAN,tr|E9PKI6|E9PKI6_HUMAN,tr|A0A1W2PQ43|A0A1W2PQ43_HUMAN,tr|E9PK91|E9PK91_HUMAN,tr|E9PJA7|E9PJA7_HUMAN,tr|E9PK09|E9PK09_HUMAN,tr|E9PQN2|E9PQN2_HUMAN" 7 1608.8471 3.34 65458 13574 2 1608.841263 805.4308 Bcl-2-associated transcription factor 1 OS=Homo sapiens OX=9606 GN=BCLAF1 PE=1 SV=2 6.38 2529.8 - 1.85E+06 - - - -3.6498 - 2.186 0.548 - 229.9 1 1 0 -0.0059 15 0 0 0 6.46E+07 1.93E+07 - - - 5.0094 0.9995 221125_WJC_METTL3_EV_vs_WT_F05.13575.13575.3 0.124 13/64 K.MAPVPLDDSNR[166.11]PASLTK.D "sp|Q9NYF8|BCLF1_HUMAN,tr|E9PKI6|E9PKI6_HUMAN,tr|A0A1W2PQ43|A0A1W2PQ43_HUMAN,tr|E9PK91|E9PK91_HUMAN,tr|E9PJA7|E9PJA7_HUMAN,tr|E9PK09|E9PK09_HUMAN,tr|E9PQN2|E9PQN2_HUMAN" 7 1820.933 - 65459 13575 3 1820.93172 607.9849 Bcl-2-associated transcription factor 1 OS=Homo sapiens OX=9606 GN=BCLAF1 PE=1 SV=2 5.71 2529.9 - 2.94E+06 - - - -0.7051 - 2.226 0.291 - 119 1 2 0 -0.0013 17 0 0 0 - - - - - 3.8056 0.9993 221125_WJC_METTL3_EV_vs_WT_F05.13583.13583.2 3.69E-05 16/24 R.IEDVTPIPSDSTR.R "sp|P62263|RS14_HUMAN,tr|A0A2R8Y811|A0A2R8Y811_HUMAN" 2 1428.7096 1.44 65465 13583 2 1428.704365 715.3621 40S ribosomal protein S14 OS=Homo sapiens OX=9606 GN=RPS14 PE=1 SV=3 4.03 2530.9 - 2.78E+06 - - - -3.6914 - 2.364 0.564 - 807.6 1 2 0 -0.0053 13 0 0 0 1.22E+09 8.43E+08 - - - 5.4132 0.9998 221125_WJC_METTL3_EV_vs_WT_F05.13584.13584.4 1.18E-06 18/96 K.MAPVPLDDSNRPASLTK.D "sp|Q9NYF8|BCLF1_HUMAN,tr|E9PKI6|E9PKI6_HUMAN,tr|A0A1W2PQ43|A0A1W2PQ43_HUMAN,tr|E9PK91|E9PK91_HUMAN,tr|E9PJA7|E9PJA7_HUMAN,tr|E9PK09|E9PK09_HUMAN,tr|E9PQN2|E9PQN2_HUMAN" 7 1810.9247 0.98 65466 13584 4 1810.919546 453.7385 Bcl-2-associated transcription factor 1 OS=Homo sapiens OX=9606 GN=BCLAF1 PE=1 SV=2 5.71 2531 - 1.34E+06 - - - -2.8648 - 2.915 0.448 - 317.6 1 2 0 -0.0052 17 0 0 0 1.74E+07 1.78E+07 - - - 3.4954 0.9997 221125_WJC_METTL3_EV_vs_WT_F05.13585.13585.3 0.00775 Nov-36 K.SC[160.03]LLHQFTEK.K "sp|P61106|RAB14_HUMAN,tr|X6RFL8|X6RFL8_HUMAN" 2 1261.6125 0.99 65467 13585 3 1261.611652 421.5448 Ras-related protein Rab-14 OS=Homo sapiens OX=9606 GN=RAB14 PE=1 SV=4 6.46 2531.1 - 1.46E+06 - - - -0.6785 - 2.086 0.323 - 211.9 1 2 0 -0.0009 10 0 0 0 4.17E+07 4.22E+07 - - - 4.2881 0.9801 221125_WJC_METTL3_EV_vs_WT_F05.13586.13586.2 0.0169 20-Nov R.EK[136.11]QPPIDNIIR[166.11].A "sp|P52292|IMA1_HUMAN,tr|J3QLL0|J3QLL0_HUMAN,tr|J3KS65|J3KS65_HUMAN,tr|A0A7I2V3Z3|A0A7I2V3Z3_HUMAN,tr|A0A7I2YQE1|A0A7I2YQE1_HUMAN,tr|A0A7I2V487|A0A7I2V487_HUMAN,tr|A0A7I2V351|A0A7I2V351_HUMAN" 7 1339.7579 1.26 65468 13586 2 1339.754238 670.8862 Importin subunit alpha-1 OS=Homo sapiens OX=9606 GN=KPNA2 PE=1 SV=1 6.17 2531.2 - 1.14E+06 - - - -2.7109 - 1.866 0.311 - 407.8 1 2 1 -0.0036 11 0 0 0 2.06E+07 1.64E+07 - - - 3.0244 0.953 221125_WJC_METTL3_EV_vs_WT_F05.13588.13588.2 2.25E-08 16/28 A.PVPLDDSNR[166.11]PASLTK[136.11].D "sp|Q9NYF8|BCLF1_HUMAN,tr|E9PKI6|E9PKI6_HUMAN,tr|A0A1W2PQ43|A0A1W2PQ43_HUMAN,tr|E9PK91|E9PK91_HUMAN,tr|E9PJA7|E9PJA7_HUMAN,tr|E9PK09|E9PK09_HUMAN,tr|E9PQN2|E9PQN2_HUMAN" 7 1626.8696 3.34 65470 13588 2 1626.863375 814.4421 Bcl-2-associated transcription factor 1 OS=Homo sapiens OX=9606 GN=BCLAF1 PE=1 SV=2 6.38 2531.5 - 1.01E+06 - - - -3.8294 - 2.197 0.576 - 423.8 1 1 0 -0.0062 15 0 0 0 6.46E+07 1.93E+07 - - - 5.2285 1 221125_WJC_METTL3_EV_vs_WT_F05.13591.13591.2 0.0046 16-Dec R.HEVININLK.N "sp|P78417|GSTO1_HUMAN,tr|Q5TA01|Q5TA01_HUMAN,tr|Q5TA02|Q5TA02_HUMAN" 3 1078.6135 6.69 65471 13591 2 1078.612322 540.314 Glutathione S-transferase omega-1 OS=Homo sapiens OX=9606 GN=GSTO1 PE=1 SV=2 6.75 2531.9 - 2.86E+06 - - - -1.0866 - 2.579 0.543 - 494.3 1 2 0 -0.0012 9 0 0 0 4.42E+07 6.61E+06 - - - 5.7921 0.9999 221125_WJC_METTL3_EV_vs_WT_F05.13592.13592.3 0.00591 13/36 K.SC[160.03]LLHQFTEK[136.11].K "sp|P61106|RAB14_HUMAN,tr|X6RFL8|X6RFL8_HUMAN" 2 1269.6267 0.99 65472 13592 3 1269.624511 424.2162 Ras-related protein Rab-14 OS=Homo sapiens OX=9606 GN=RAB14 PE=1 SV=4 6.46 2532 - 1.92E+06 - - - -1.7304 - 2.479 0.43 - 308.7 1 2 0 -0.0022 10 0 0 0 4.17E+07 4.23E+07 - - - 5.9848 0.9998 221125_WJC_METTL3_EV_vs_WT_F05.13594.13594.3 3.59E-08 15/64 K.FATDGEGYKPC[160.03]DPQVIR.D "sp|Q01082|SPTB2_HUMAN,tr|A0A087WUZ3|A0A087WUZ3_HUMAN,tr|F8W6C1|F8W6C1_HUMAN" 3 1951.9098 1.65 65474 13594 3 1951.9007 651.6439 "Spectrin beta chain, non-erythrocytic 1 OS=Homo sapiens OX=9606 GN=SPTBN1 PE=1 SV=2" 4.56 2532.3 - 778507 - - - -4.6682 - 2.314 0.596 - 207.5 1 2 0 -0.0091 17 0 0 0 1.10E+07 6.65E+06 - - - 7.3018 0.9998 221125_WJC_METTL3_EV_vs_WT_F05.13597.13597.2 4.11E-06 13/24 R.IEDVTPIPSDSTR[166.11].R "sp|P62263|RS14_HUMAN,tr|A0A2R8Y811|A0A2R8Y811_HUMAN" 2 1438.7179 1.45 65475 13597 2 1438.715617 720.3662 40S ribosomal protein S14 OS=Homo sapiens OX=9606 GN=RPS14 PE=1 SV=3 4.03 2532.7 - 6.26E+06 - - - -1.5931 - 2.304 0.535 - 539.7 1 2 0 -0.0023 13 0 0 0 1.22E+09 8.43E+08 - - - 5.1339 1 221125_WJC_METTL3_EV_vs_WT_F05.13598.13598.3 2.33E-05 18/60 R.AC[160.03]GVSR[166.11]PVIAC[160.03]SVTIK[136.11].E "sp|P55769|NH2L1_HUMAN,tr|B1AHD1|B1AHD1_HUMAN,tr|A0A3B3IUA2|A0A3B3IUA2_HUMAN,tr|A0A3B3IRU2|A0A3B3IRU2_HUMAN" 4 1734.924 1.01 65476 13598 3 1734.926429 579.3153 NHP2-like protein 1 OS=Homo sapiens OX=9606 GN=SNU13 PE=1 SV=3 8.96 2532.8 - 2.54E+06 - - - 1.4197 - 3.359 0.484 - 440.8 1 2 0 0.0025 16 0 0 0 9.17E+07 9.04E+07 - - - 7.0444 0.9997 221125_WJC_METTL3_EV_vs_WT_F05.13602.13602.2 2.05E-07 28-Dec K.TFTTQETITNAETAK[136.11].E "sp|P06744|G6PI_HUMAN,tr|A0A2R8Y6C7|A0A2R8Y6C7_HUMAN,tr|A0A0J9YYH3|A0A0J9YYH3_HUMAN,tr|K7EQ48|K7EQ48_HUMAN,tr|A0A2U3TZU2|A0A2U3TZU2_HUMAN,tr|K7ERC6|K7ERC6_HUMAN,tr|A0A0J9YXP8|A0A0J9YXP8_HUMAN,tr|A0A0J9YX90|A0A0J9YX90_HUMAN" 8 1662.8192 1.25 65480 13602 2 1662.815079 832.4169 Glucose-6-phosphate isomerase OS=Homo sapiens OX=9606 GN=GPI PE=1 SV=4 4.53 2533.3 - 568615 - - - -2.4759 - 2.309 0.589 - 387.2 1 2 0 -0.0041 15 0 0 0 7.03E+06 5.62E+06 - - - 5.4474 0.9995 221125_WJC_METTL3_EV_vs_WT_F05.13605.13605.3 1.91E-05 Dec-40 K.RGVFNVQMEPK.V sp|P05198|IF2A_HUMAN 1 1303.6707 1.65 65481 13605 3 1303.671828 435.5642 Eukaryotic translation initiation factor 2 subunit 1 OS=Homo sapiens OX=9606 GN=EIF2S1 PE=1 SV=3 8.75 2533.7 - 715339 - - - 0.8722 - 1.984 0.297 - 239.3 1 2 0 0.0011 11 0 0 0 1.64E+07 9.90E+06 - - - 3.7972 0.9999 221125_WJC_METTL3_EV_vs_WT_F05.13611.13611.2 2.70E-05 16-Nov R.QEYEQLIAK.N "sp|P35527|K1C9_HUMAN,tr|K7EQQ3|K7EQQ3_HUMAN" 2 1120.5764 155.33 65485 13611 2 1120.576887 561.2955 "Keratin, type I cytoskeletal 9 OS=Homo sapiens OX=9606 GN=KRT9 PE=1 SV=3" 4.53 2534.4 - 2.32E+06 - - - 0.3989 - 2.099 0.463 - 451.5 1 2 0 0.0004 9 0 0 0 6.57E+07 4.23E+05 - - - 4.6057 0.9994 221125_WJC_METTL3_EV_vs_WT_F05.13616.13616.2 0.000545 13/18 K.SC[160.03]LLHQFTEK.K "sp|P61106|RAB14_HUMAN,tr|X6RFL8|X6RFL8_HUMAN" 2 1261.6125 1.29 65490 13616 2 1261.609154 631.8135 Ras-related protein Rab-14 OS=Homo sapiens OX=9606 GN=RAB14 PE=1 SV=4 6.46 2535 - 558844 - - - -2.6585 - 2.098 0.419 - 742.9 1 2 0 -0.0034 10 0 0 0 8.16E+06 6.34E+06 - - - 4.203 1 221125_WJC_METTL3_EV_vs_WT_F05.13620.13620.2 1.93E-05 14/18 K.SC[160.03]LLHQFTEK[136.11].K "sp|P61106|RAB14_HUMAN,tr|X6RFL8|X6RFL8_HUMAN" 2 1269.6267 1.35 65492 13620 2 1269.626409 635.8206 Ras-related protein Rab-14 OS=Homo sapiens OX=9606 GN=RAB14 PE=1 SV=4 6.46 2535.6 - 709470 - - - -0.2355 - 2.768 0.523 - 1077.8 1 2 0 -0.0003 10 0 0 0 8.16E+06 6.04E+06 - - - 5.7457 0.9995 221125_WJC_METTL3_EV_vs_WT_F05.13621.13621.3 0.0126 14/36 R.R[166.11]K[136.11]PFYPALIR[166.11].Y "sp|O00746|NDKM_HUMAN,tr|Q4TT34|Q4TT34_HUMAN,tr|H0Y6J0|H0Y6J0_HUMAN,tr|F2Z2X0|F2Z2X0_HUMAN,tr|A2IDC9|A2IDC9_HUMAN" 5 1287.781 1.86 65493 13621 3 1287.780259 430.2676 "Nucleoside diphosphate kinase, mitochondrial OS=Homo sapiens OX=9606 GN=NME4 PE=1 SV=1" 11 2535.7 - 1.30E+06 - - - -0.577 - 1.929 0.3 - 305.9 1 2 0 -0.0007 10 0 0 0 9.00E+08 4.83E+08 - - - 3.8032 1 221125_WJC_METTL3_EV_vs_WT_F05.13622.13622.3 1.10E-10 20/52 R.STAYEDYYYHPPPR[166.11].M "sp|O43390|HNRPR_HUMAN,tr|B4DT28|B4DT28_HUMAN,tr|A0A6Q8PH35|A0A6Q8PH35_HUMAN,tr|A0A286YEZ8|A0A286YEZ8_HUMAN" 4 1767.7768 1.35 65494 13622 3 1767.779885 590.2662 Heterogeneous nuclear ribonucleoprotein R OS=Homo sapiens OX=9606 GN=HNRNPR PE=1 SV=1 5.3 2535.8 - 1.13E+06 - - - 1.7338 - 3.058 0.683 - 500.5 1 2 0 0.0031 14 0 0 0 1.59E+08 1.18E+08 - - - 9.1244 1 221125_WJC_METTL3_EV_vs_WT_F05.13629.13629.2 6.36E-12 19/32 R.GIEQAVQSHAVAEEEAR.K "sp|Q16891|MIC60_HUMAN,tr|B9A067|B9A067_HUMAN,tr|C9J406|C9J406_HUMAN,tr|H7C463|H7C463_HUMAN" 4 1822.881 3.28 65499 13629 2 1822.883792 912.4478 MICOS complex subunit MIC60 OS=Homo sapiens OX=9606 GN=IMMT PE=1 SV=1 4.48 2536.7 - 878695 - - - 1.5563 - 4.011 0.679 - 1214.4 1 2 0 0.0028 17 0 0 0 1.57E+07 4.78E+06 - - - 7.4702 1 221125_WJC_METTL3_EV_vs_WT_F05.13630.13630.2 1.71E-07 15/24 K.TGGTQTDLFTC[160.03]GK[136.11].C "sp|P23193|TCEA1_HUMAN,sp|Q15560|TCEA2_HUMAN,tr|B7Z4S1|B7Z4S1_HUMAN,tr|A0A0A0MT58|A0A0A0MT58_HUMAN,tr|Q5JRI7|Q5JRI7_HUMAN,tr|A0A1W2PRL9|A0A1W2PRL9_HUMAN,tr|A0A1W2PPZ5|A0A1W2PPZ5_HUMAN" 7 1392.6435 1.12 65500 13630 2 1392.644158 697.329 Transcription elongation factor A protein 1 OS=Homo sapiens OX=9606 GN=TCEA1 PE=1 SV=2 5.5 2536.9 - 744057 - - - 0.4868 - 2.649 0.575 - 919.7 1 2 0 0.0007 13 0 0 0 4.08E+07 3.63E+07 - - - 5.788 0.9982 221125_WJC_METTL3_EV_vs_WT_F05.13631.13631.3 0.00354 Oct-36 R.RKPFYPALIR.Y "sp|O00746|NDKM_HUMAN,tr|Q4TT34|Q4TT34_HUMAN,tr|H0Y6J0|H0Y6J0_HUMAN,tr|F2Z2X0|F2Z2X0_HUMAN,tr|A2IDC9|A2IDC9_HUMAN" 5 1259.7503 1.86 65501 13631 3 1259.748213 420.924 "Nucleoside diphosphate kinase, mitochondrial OS=Homo sapiens OX=9606 GN=NME4 PE=1 SV=1" 11 2536.9 - 2.94E+06 - - - -1.6265 - 2.055 0.224 - 157.2 1 2 0 -0.002 10 0 0 0 9.01E+08 4.83E+08 - - - 3.1403 0.9999 221125_WJC_METTL3_EV_vs_WT_F05.13632.13632.3 0.000228 13/48 R.IEDVTPIPSDSTR.R "sp|P62263|RS14_HUMAN,tr|A0A2R8Y811|A0A2R8Y811_HUMAN" 2 1428.7096 0.96 65502 13632 3 1428.706949 477.2438 40S ribosomal protein S14 OS=Homo sapiens OX=9606 GN=RPS14 PE=1 SV=3 4.03 2537 - 1.83E+06 - - - -1.8828 - 2.293 0.464 - 281.8 1 2 0 -0.0027 13 0 0 0 7.45E+07 7.77E+07 - - - 5.9624 0.9983 221125_WJC_METTL3_EV_vs_WT_F05.13633.13633.2 1.12E-06 22-Dec K.EVDEQMLNVQNK[136.11].N "sp|Q9BVA1|TBB2B_HUMAN,sp|P07437|TBB5_HUMAN,sp|Q13885|TBB2A_HUMAN,sp|P68371|TBB4B_HUMAN,tr|Q5ST81|Q5ST81_HUMAN,tr|Q5JP53|Q5JP53_HUMAN" 6 1453.6962 0.56 65503 13633 2 1453.702937 727.8554 Tubulin beta-2B chain OS=Homo sapiens OX=9606 GN=TUBB2B PE=1 SV=1 4.14 2537.1 - 1.75E+06 - - - 4.6041 - 2.167 0.532 - 399.9 1 2 0 0.0067 12 0 0 0 1.44E+08 2.58E+08 - - - 5.003 0.9999 221125_WJC_METTL3_EV_vs_WT_F05.13634.13634.3 0.000548 13/48 R.IEDVTPIPSDSTR[166.11].R "sp|P62263|RS14_HUMAN,tr|A0A2R8Y811|A0A2R8Y811_HUMAN" 2 1438.7179 1.84 65504 13634 3 1438.72068 480.5799 40S ribosomal protein S14 OS=Homo sapiens OX=9606 GN=RPS14 PE=1 SV=3 4.03 2537.1 - 1.47E+06 - - - 1.926 - 2.467 0.41 - 292.4 1 2 0 0.0028 13 0 0 0 7.21E+07 3.93E+07 - - - 5.5586 1 221125_WJC_METTL3_EV_vs_WT_F05.13640.13640.2 4.58E-07 15/24 K.TGGTQTDLFTC[160.03]GK.C "sp|P23193|TCEA1_HUMAN,sp|Q15560|TCEA2_HUMAN,tr|B7Z4S1|B7Z4S1_HUMAN,tr|A0A0A0MT58|A0A0A0MT58_HUMAN,tr|Q5JRI7|Q5JRI7_HUMAN,tr|A0A1W2PRL9|A0A1W2PRL9_HUMAN,tr|A0A1W2PPZ5|A0A1W2PPZ5_HUMAN" 7 1384.6293 1.14 65508 13640 2 1384.625968 693.3219 Transcription elongation factor A protein 1 OS=Homo sapiens OX=9606 GN=TCEA1 PE=1 SV=2 5.5 2537.9 - 1.02E+06 - - - -2.392 - 2.785 0.602 - 1180.6 1 2 0 -0.0033 13 0 0 0 4.13E+07 3.63E+07 - - - 6.1151 1 221125_WJC_METTL3_EV_vs_WT_F05.13642.13642.3 1.55E-06 13/60 R.HLLVSNVGGDGEEIER.F "sp|O75694|NU155_HUMAN,tr|E9PF10|E9PF10_HUMAN" 2 1722.8537 1.43 65510 13642 3 1722.852347 575.2918 Nuclear pore complex protein Nup155 OS=Homo sapiens OX=9606 GN=NUP155 PE=1 SV=1 4.4 2538 - 3.23E+06 - - - -0.772 - 2.754 0.584 - 298.9 1 2 0 -0.0013 16 0 0 0 5.13E+07 3.58E+07 - - - 7.65 1 221125_WJC_METTL3_EV_vs_WT_F05.13651.13651.3 1.10E-09 20/60 R.EALLSSAVDHGSDEVK.F "sp|P78371|TCPB_HUMAN,tr|F8VQ14|F8VQ14_HUMAN,tr|F5GWF6|F5GWF6_HUMAN" 3 1655.8002 0.55 65518 13651 3 1655.797425 552.9407 T-complex protein 1 subunit beta OS=Homo sapiens OX=9606 GN=CCT2 PE=1 SV=4 4.31 2539 - 1.26E+06 - - - -1.7031 - 3.978 0.59 - 732.6 1 2 0 -0.0028 16 0 0 0 5.74E+08 1.03E+09 - - - 8.66 0.9998 221125_WJC_METTL3_EV_vs_WT_F05.13652.13652.3 0.00134 14/52 K.NLDK[136.11]DMYGDDLEAR[166.11].L "sp|Q13573|SNW1_HUMAN,tr|G3V4X8|G3V4X8_HUMAN,tr|G3V3A4|G3V3A4_HUMAN" 3 1671.7529 1.21 65519 13652 3 1671.752418 558.2582 SNW domain-containing protein 1 OS=Homo sapiens OX=9606 GN=SNW1 PE=1 SV=1 4.04 2539.1 - 601781 - - - -0.3003 - 2.5 0.435 - 271.8 1 2 1 -0.0005 14 0 0 0 1.93E+07 1.60E+07 - - - 5.8248 0.9999 221125_WJC_METTL3_EV_vs_WT_F05.13653.13653.3 0.000427 Dec-36 K.TVDLK[136.11]PDWGK[136.11].G "sp|P31948|STIP1_HUMAN,tr|F5GXD8|F5GXD8_HUMAN,tr|F5H783|F5H783_HUMAN" 3 1173.6365 0.69 65520 13653 3 1173.633939 392.2194 Stress-induced-phosphoprotein 1 OS=Homo sapiens OX=9606 GN=STIP1 PE=1 SV=1 5.63 2539.3 - 389170 - - - -2.16 - 1.933 0.459 - 197.5 1 2 0 -0.0025 10 0 0 0 1.29E+07 1.85E+07 - - - 5.5815 1 221125_WJC_METTL3_EV_vs_WT_F05.13656.13656.3 3.15E-10 18/60 R.EALLSSAVDHGSDEVK[136.11].F "sp|P78371|TCPB_HUMAN,tr|F8VQ14|F8VQ14_HUMAN,tr|F5GWF6|F5GWF6_HUMAN" 3 1663.8144 0.55 65521 13656 3 1663.813633 555.6121 T-complex protein 1 subunit beta OS=Homo sapiens OX=9606 GN=CCT2 PE=1 SV=4 4.31 2539.7 - 6.69E+06 - - - -0.488 - 3.822 0.572 - 650.7 1 2 0 -0.0008 16 0 0 0 5.74E+08 1.03E+09 - - - 8.3573 1 221125_WJC_METTL3_EV_vs_WT_F05.13666.13666.3 1.48E-07 18/64 R.GIEQAVQSHAVAEEEAR.K "sp|Q16891|MIC60_HUMAN,tr|B9A067|B9A067_HUMAN,tr|C9J406|C9J406_HUMAN,tr|H7C463|H7C463_HUMAN" 4 1822.881 1.72 65529 13666 3 1822.879615 608.6343 MICOS complex subunit MIC60 OS=Homo sapiens OX=9606 GN=IMMT PE=1 SV=1 4.48 2540.9 - 2.16E+07 - - - -0.7351 - 3.631 0.561 - 349.5 1 2 0 -0.0013 17 0 0 0 3.53E+08 2.05E+08 - - - 8.0519 0.9999 221125_WJC_METTL3_EV_vs_WT_F05.13667.13667.3 4.26E-07 14/52 R.SEREDEVLLVSSSR.Y "sp|Q8NFP7|NUD10_HUMAN,sp|Q96G61|NUD11_HUMAN" 2 1604.8006 1.18 65530 13667 3 1604.798863 535.9408 Diphosphoinositol polyphosphate phosphohydrolase 3-alpha OS=Homo sapiens OX=9606 GN=NUDT10 PE=1 SV=1 4.41 2541 - 1.45E+06 - - - -1.0693 - 2.92 0.521 - 352.8 1 2 1 -0.0017 14 0 0 0 5.76E+07 4.86E+07 - - - 7.1959 1 221125_WJC_METTL3_EV_vs_WT_F05.13668.13668.2 4.35E-05 17/30 R.EALLSSAVDHGSDEVK.F "sp|P78371|TCPB_HUMAN,tr|F8VQ14|F8VQ14_HUMAN,tr|F5GWF6|F5GWF6_HUMAN" 3 1655.8002 0.54 65531 13668 2 1655.795417 828.9074 T-complex protein 1 subunit beta OS=Homo sapiens OX=9606 GN=CCT2 PE=1 SV=4 4.31 2541.1 - 920010 - - - -2.9158 - 3.321 0.622 - 812 1 2 0 -0.0048 16 0 0 0 5.25E+07 9.72E+07 - - - 6.5845 0.7983 221125_WJC_METTL3_EV_vs_WT_F05.13669.13669.3 0.868 Nov-48 K.VAQLQTDYDALKR.Q sp|Q66GS9|CP135_HUMAN 1 1519.7995 16.88 65532 13669 3 1519.80151 507.6071 Centrosomal protein of 135 kDa OS=Homo sapiens OX=9606 GN=CEP135 PE=1 SV=2 5.93 2541.3 - 871451 - - - 1.3508 - 1.555 0.05 - 68.7 2 2 0 0.0021 13 0 0 0 3.11E+07 1.84E+06 - - - 0.1545 1 221125_WJC_METTL3_EV_vs_WT_F05.13670.13670.3 4.34E-10 22/72 R.LLEAQAC[160.03]TGGIIHPTTGQK.L sp|P15924|DESP_HUMAN 1 1994.0255 0.92 65533 13670 3 1994.024469 665.6824 Desmoplakin OS=Homo sapiens OX=9606 GN=DSP PE=1 SV=3 6.74 2541.4 - 716883 - - - -0.5226 - 3.798 0.647 - 516 1 2 0 -0.001 19 0 0 0 1.05E+07 1.14E+07 - - - 9.0317 0.9998 221125_WJC_METTL3_EV_vs_WT_F05.13671.13671.3 0.0207 Dec-36 K.TVDLKPDWGK.G "sp|P31948|STIP1_HUMAN,tr|F5GXD8|F5GXD8_HUMAN,tr|F5H783|F5H783_HUMAN" 3 1157.6081 0.67 65534 13671 3 1157.606599 386.8766 Stress-induced-phosphoprotein 1 OS=Homo sapiens OX=9606 GN=STIP1 PE=1 SV=1 5.63 2541.5 - 627336 - - - -1.2742 - 2.291 0.351 - 171.1 1 2 0 -0.0015 10 0 0 0 1.30E+07 1.94E+07 - - - 4.8739 1 221125_WJC_METTL3_EV_vs_WT_F05.13672.13672.3 2.01E-07 16/56 K.FHPNGSTLASAGFDR.L sp|Q96DI7|SNR40_HUMAN 1 1575.743 1.53 65535 13672 3 1575.742024 526.2549 U5 small nuclear ribonucleoprotein 40 kDa protein OS=Homo sapiens OX=9606 GN=SNRNP40 PE=1 SV=1 6.74 2541.6 - 895049 - - - -0.6219 - 2.619 0.534 - 360.5 1 2 0 -0.001 15 0 0 0 2.87E+07 1.87E+07 - - - 7.0056 0.9999 221125_WJC_METTL3_EV_vs_WT_F05.13673.13673.3 2.00E-05 Dec-40 K.VYNYNHLMPTR[166.11].Y "sp|P61353|RL27_HUMAN,tr|K7ELC7|K7ELC7_HUMAN" 2 1416.6848 1.69 65536 13673 3 1416.685871 473.2355 60S ribosomal protein L27 OS=Homo sapiens OX=9606 GN=RPL27 PE=1 SV=2 8.57 2541.8 - 412041 - - - 0.7736 - 1.98 0.439 - 190.1 1 2 0 0.0011 11 0 0 0 9.80E+06 5.79E+06 - - - 5.3747 0.9879 221125_WJC_METTL3_EV_vs_WT_F05.13675.13675.3 0.42 Jul-32 K.DDYVHEFC[160.03]R.Y sp|Q13564|ULA1_HUMAN 1 1239.4979 1.4 65538 13675 3 1239.495621 414.1732 NEDD8-activating enzyme E1 regulatory subunit OS=Homo sapiens OX=9606 GN=NAE1 PE=1 SV=1 4.54 2542 - 288393 - - - -1.8161 - 1.265 0.244 - 85.4 1 2 0 -0.0023 9 0 0 0 2.55E+06 1.83E+06 - - - 1.9682 0.9999 221125_WJC_METTL3_EV_vs_WT_F05.13681.13681.2 1.36E-08 13/28 K.ESC[160.03]DPSLGLAGPGAK[136.11].S "sp|O75410|TACC1_HUMAN,tr|E5RFM9|E5RFM9_HUMAN,tr|R4GMT7|R4GMT7_HUMAN,tr|E5RJG6|E5RJG6_HUMAN" 4 1465.6962 2.64 65542 13681 2 1465.695141 733.8554 Transforming acidic coiled-coil-containing protein 1 OS=Homo sapiens OX=9606 GN=TACC1 PE=1 SV=2 4.37 2542.7 - 1.14E+06 - - - -0.7525 - 2.276 0.612 - 527.5 1 2 0 -0.0011 15 0 0 0 7.24E+07 2.75E+07 - - - 5.5828 0.9993 221125_WJC_METTL3_EV_vs_WT_F05.13683.13683.3 0.000599 Oct-40 K.C[160.03]K[136.11]FEEAQSILK[136.11].A sp|P49792|RBP2_HUMAN 1 1367.709 0.24 65544 13683 3 1367.70704 456.9103 E3 SUMO-protein ligase RanBP2 OS=Homo sapiens OX=9606 GN=RANBP2 PE=1 SV=2 6.14 2542.9 - 902468 - - - -1.4235 - 2.115 0.384 - 188.7 1 2 1 -0.0019 11 0 0 0 5.84E+06 2.44E+07 - - - 4.9486 0.9999 221125_WJC_METTL3_EV_vs_WT_F05.13686.13686.3 3.71E-07 13/36 K.LK[136.11]EENFFGPK[136.11].E sp|Q9NZI8|IF2B1_HUMAN 1 1223.6521 1.64 65547 13686 3 1223.649379 408.8913 Insulin-like growth factor 2 mRNA-binding protein 1 OS=Homo sapiens OX=9606 GN=IGF2BP1 PE=1 SV=2 6.14 2543.3 - 570767 - - - -2.2433 - 2.454 0.594 - 169 1 2 1 -0.0027 10 0 0 0 1.56E+07 9.49E+06 - - - 7.7835 1 221125_WJC_METTL3_EV_vs_WT_F05.13687.13687.3 0.000135 Nov-56 K.FHPNGSTLASAGFDR[166.11].L sp|Q96DI7|SNR40_HUMAN 1 1585.7513 1.46 65548 13687 3 1585.750805 529.591 U5 small nuclear ribonucleoprotein 40 kDa protein OS=Homo sapiens OX=9606 GN=SNRNP40 PE=1 SV=1 6.74 2543.4 - 549413 - - - -0.2958 - 2.573 0.457 - 181.9 1 2 0 -0.0005 15 0 0 0 2.74E+07 1.88E+07 - - - 6.101 1 221125_WJC_METTL3_EV_vs_WT_F05.13688.13688.3 8.94E-05 Oct-40 K.VYNYNHLMPTR.Y "sp|P61353|RL27_HUMAN,tr|K7ELC7|K7ELC7_HUMAN" 2 1406.6765 1.6 65549 13688 3 1406.677062 469.8994 60S ribosomal protein L27 OS=Homo sapiens OX=9606 GN=RPL27 PE=1 SV=2 8.57 2543.6 - 378502 - - - 0.396 - 2.135 0.472 - 110.8 1 2 0 0.0006 11 0 0 0 9.27E+06 5.79E+06 - - - 5.9569 1 221125_WJC_METTL3_EV_vs_WT_F05.13689.13689.2 6.80E-11 16/30 R.EPSVPASC[160.03]AVSATYER[166.11].S "sp|Q92615|LAR4B_HUMAN,tr|H0Y641|H0Y641_HUMAN,tr|H0Y4V9|H0Y4V9_HUMAN" 3 1732.7966 1.31 65550 13689 2 1732.798504 867.4056 La-related protein 4B OS=Homo sapiens OX=9606 GN=LARP4B PE=1 SV=3 4.53 2543.7 - 337557 - - - 1.1161 - 2.919 0.724 - 474.4 1 2 0 0.0019 16 0 0 0 2.59E+08 1.98E+08 - - - 7.0216 1 221125_WJC_METTL3_EV_vs_WT_F05.13691.13691.2 7.82E-06 14/30 R.EPSVPASC[160.03]AVSATYER.S "sp|Q92615|LAR4B_HUMAN,tr|H0Y641|H0Y641_HUMAN,tr|H0Y4V9|H0Y4V9_HUMAN" 3 1722.7883 1.31 65552 13691 2 1722.791443 862.4014 La-related protein 4B OS=Homo sapiens OX=9606 GN=LARP4B PE=1 SV=3 4.53 2543.9 - 314395 - - - 1.8244 - 2.735 0.63 - 335.9 1 2 0 0.0031 16 0 0 0 2.59E+08 1.98E+08 - - - 6.1668 0.9799 221125_WJC_METTL3_EV_vs_WT_F05.13692.13692.3 0.00287 Sep-44 K.IHIPGGLSPESK[136.11].K sp|P57772|SELB_HUMAN 1 1241.6859 1.19 65553 13692 3 1241.681666 414.9026 Selenocysteine-specific elongation factor OS=Homo sapiens OX=9606 GN=EEFSEC PE=1 SV=4 6.75 2544.1 - 246906 - - - -3.4397 - 1.879 0.188 - 95.2 1 2 0 -0.0043 12 0 0 0 5.14E+06 4.33E+06 - - - 2.3831 0.9986 221125_WJC_METTL3_EV_vs_WT_F05.13693.13693.2 0.00113 26-Aug R.TNTPQGVLPSSQLK[136.11].S "sp|Q14004|CDK13_HUMAN,tr|A0A2R8Y4Z0|A0A2R8Y4Z0_HUMAN,tr|A0A2R8YF61|A0A2R8YF61_HUMAN,tr|A0A2R8Y7W5|A0A2R8Y7W5_HUMAN" 4 1476.8028 1.68 65554 13693 2 1476.801518 739.4087 Cyclin-dependent kinase 13 OS=Homo sapiens OX=9606 GN=CDK13 PE=1 SV=2 8.41 2544.2 - 200564 - - - -0.8397 - 1.792 0.23 - 208.5 1 2 0 -0.0012 14 0 0 0 2.25E+06 1.34E+06 - - - 2.2032 0.9994 221125_WJC_METTL3_EV_vs_WT_F05.13696.13696.2 0.00697 24-Jul K.GGSGSGPTIEEVD.- "sp|P0DMV8|HS71A_HUMAN,sp|P0DMV9|HS71B_HUMAN,tr|V9GZ37|V9GZ37_HUMAN,tr|A0A0G2JIW1|A0A0G2JIW1_HUMAN" 4 1203.5255 - 65555 13696 2 1203.524944 602.77 Heat shock 70 kDa protein 1A OS=Homo sapiens OX=9606 GN=HSPA1A PE=1 SV=1 3.88 2544.6 - 1.01E+07 - - - -0.4836 - 1.546 0.359 - 109.3 1 2 0 -0.0006 13 0 0 0 - - - - - 2.8106 0.9486 221125_WJC_METTL3_EV_vs_WT_F05.13697.13697.3 0.151 Aug-44 K.MK[136.11]YDESDNAFIR[166.11].A "sp|O43615|TIM44_HUMAN,tr|M0QXU7|M0QXU7_HUMAN" 2 1505.6939 0.99 65556 13697 3 1505.692566 502.9053 Mitochondrial import inner membrane translocase subunit TIM44 OS=Homo sapiens OX=9606 GN=TIMM44 PE=1 SV=2 4.56 2544.6 - 4.04E+06 - - - -0.9185 - 1.47 0.189 - 102.4 1 2 1 -0.0014 12 0 0 0 3.99E+07 4.05E+07 - - - 1.7147 0.9999 221125_WJC_METTL3_EV_vs_WT_F05.13698.13698.3 3.63E-06 13/44 K.MKYDESDNAFIR.A "sp|O43615|TIM44_HUMAN,tr|M0QXU7|M0QXU7_HUMAN" 2 1487.6715 1.03 65557 13698 3 1487.671759 496.8978 Mitochondrial import inner membrane translocase subunit TIM44 OS=Homo sapiens OX=9606 GN=TIMM44 PE=1 SV=2 4.56 2544.7 - 3.89E+06 - - - 0.1882 - 2.328 0.556 - 318.3 1 2 1 0.0003 12 0 0 0 4.18E+07 4.05E+07 - - - 7.081 0.9999 221125_WJC_METTL3_EV_vs_WT_F05.13699.13699.3 3.43E-09 19/60 R.VFDK[136.11]EGNGTVMGAELR[166.11].H "sp|P08590|MYL3_HUMAN,sp|P05976|MYL1_HUMAN,sp|P60660|MYL6_HUMAN,tr|F8W1R7|F8W1R7_HUMAN,tr|G3V1V0|G3V1V0_HUMAN,tr|B7Z6Z4|B7Z6Z4_HUMAN,tr|F8VZU9|F8VZU9_HUMAN,tr|G8JLA2|G8JLA2_HUMAN,tr|H0YI43|H0YI43_HUMAN,tr|F8W180|F8W180_HUMAN,tr|G3V1Y7|G3V1Y7_HUMAN,tr|J3KND3|J3KND3_HUMAN,tr|F8VPF3|F8VPF3_HUMAN" 13 1739.8631 1.52 65558 13699 3 1739.861762 580.9617 Myosin light chain 3 OS=Homo sapiens OX=9606 GN=MYL3 PE=1 SV=3 4.68 2544.8 - 1.81E+06 - - - -0.792 - 3.16 0.474 - 433.1 1 2 1 -0.0014 16 0 0 0 3.90E+07 2.57E+07 - - - 6.7765 0.9999 221125_WJC_METTL3_EV_vs_WT_F05.13700.13700.3 1.66E-06 15/36 K.LKEENFFGPK.E sp|Q9NZI8|IF2B1_HUMAN 1 1207.6237 1.62 65559 13700 3 1207.622502 403.5485 Insulin-like growth factor 2 mRNA-binding protein 1 OS=Homo sapiens OX=9606 GN=IGF2BP1 PE=1 SV=2 6.14 2544.9 - 1.36E+06 - - - -1.0119 - 2.477 0.522 - 255.3 1 2 1 -0.0012 10 0 0 0 1.56E+07 9.62E+06 - - - 7.0084 0.9998 221125_WJC_METTL3_EV_vs_WT_F05.13701.13701.3 4.27E-05 13/40 K.MK[136.11]EIAEAYLGK[136.11].T "sp|P11142|HSP7C_HUMAN,tr|E9PQQ4|E9PQQ4_HUMAN,tr|E9PKE3|E9PKE3_HUMAN,tr|E9PN89|E9PN89_HUMAN,tr|E9PLF4|E9PLF4_HUMAN,tr|E9PI65|E9PI65_HUMAN,tr|E9PK54|E9PK54_HUMAN,tr|E9PPY6|E9PPY6_HUMAN,tr|E9PQK7|E9PQK7_HUMAN" 9 1267.6817 0.16 65560 13701 3 1267.681144 423.5678 Heat shock cognate 71 kDa protein OS=Homo sapiens OX=9606 GN=HSPA8 PE=1 SV=1 5.9 2545 - 1.31E+06 - - - -0.4465 - 2.305 0.478 - 285.8 1 2 1 -0.0006 11 0 0 0 1.49E+07 9.27E+07 - - - 6.2414 0.9999 221125_WJC_METTL3_EV_vs_WT_F05.13703.13703.3 0.117 13/36 K.K[136.11]SDVEAIFSK[136.11].Y "sp|P0DMR1|HNRC4_HUMAN,sp|P07910|HNRPC_HUMAN,sp|O60812|HNRC1_HUMAN,sp|B2RXH8|HNRC2_HUMAN,sp|B7ZW38|HNRC3_HUMAN,tr|G3V251|G3V251_HUMAN,tr|B4DY08|B4DY08_HUMAN,tr|G3V575|G3V575_HUMAN,tr|B4DSU6|B4DSU6_HUMAN,tr|G3V3K6|G3V3K6_HUMAN,tr|B2R5W2|B2R5W2_HUMAN,tr|G3V4C1|G3V4C1_HUMAN,tr|A0A0G2JPF8|A0A0G2JPF8_HUMAN,tr|A0A0G2JNQ3|A0A0G2JNQ3_HUMAN,tr|G3V576|G3V576_HUMAN,tr|G3V5X6|G3V5X6_HUMAN,tr|G3V2H6|G3V2H6_HUMAN,tr|G3V4W0|G3V4W0_HUMAN,tr|G3V555|G3V555_HUMAN,tr|G3V4M8|G3V4M8_HUMAN,tr|G3V2Q1|G3V2Q1_HUMAN" 21 1138.6205 0.001 65562 13703 3 1138.619195 380.5474 Heterogeneous nuclear ribonucleoprotein C-like 4 OS=Homo sapiens OX=9606 GN=HNRNPCL4 PE=3 SV=1 6.07 2545.3 - 701039 - - - -1.1373 - 2.344 0.362 - 344.1 1 2 0 -0.0013 10 0 0 0 0.00E+00 1.90E+08 - - - 5.0634 0.9977 221125_WJC_METTL3_EV_vs_WT_F05.13707.13707.2 0.000873 22-Jul K.MK[136.11]YDESDNAFIR[166.11].A "sp|O43615|TIM44_HUMAN,tr|M0QXU7|M0QXU7_HUMAN" 2 1505.6939 0.71 65566 13707 2 1505.692409 753.8543 Mitochondrial import inner membrane translocase subunit TIM44 OS=Homo sapiens OX=9606 GN=TIMM44 PE=1 SV=2 4.56 2545.8 - 459498 - - - -1.0228 - 1.82 0.499 - 81.1 1 2 1 -0.0015 12 0 0 0 2.64E+06 3.72E+06 - - - 4.3018 0.9987 221125_WJC_METTL3_EV_vs_WT_F05.13708.13708.2 2.25E-06 22-Oct K.MKYDESDNAFIR.A "sp|O43615|TIM44_HUMAN,tr|M0QXU7|M0QXU7_HUMAN" 2 1487.6715 0.71 65567 13708 2 1487.670815 744.843 Mitochondrial import inner membrane translocase subunit TIM44 OS=Homo sapiens OX=9606 GN=TIMM44 PE=1 SV=2 4.56 2545.9 - 272010 - - - -0.4463 - 2.077 0.55 - 239.9 1 2 1 -0.0007 12 0 0 0 2.64E+06 3.72E+06 - - - 5.0263 0.9973 221125_WJC_METTL3_EV_vs_WT_F05.13709.13709.3 0.00748 Aug-40 K.MKEIAEAYLGK.T "sp|P11142|HSP7C_HUMAN,tr|E9PQQ4|E9PQQ4_HUMAN,tr|E9PKE3|E9PKE3_HUMAN,tr|E9PN89|E9PN89_HUMAN,tr|E9PLF4|E9PLF4_HUMAN,tr|E9PI65|E9PI65_HUMAN,tr|E9PK54|E9PK54_HUMAN,tr|E9PPY6|E9PPY6_HUMAN,tr|E9PQK7|E9PQK7_HUMAN" 9 1251.6533 0.16 65568 13709 3 1251.652248 418.225 Heat shock cognate 71 kDa protein OS=Homo sapiens OX=9606 GN=HSPA8 PE=1 SV=1 5.9 2546 - 252522 - - - -0.8485 - 1.736 0.321 - 110.1 1 2 1 -0.0011 11 0 0 0 1.49E+07 9.27E+07 - - - 3.6855 0.9997 221125_WJC_METTL3_EV_vs_WT_F05.13712.13712.2 2.82E-05 15/32 R.AIGGGLSSVGGGSSTIK.Y "sp|P48668|K2C6C_HUMAN,sp|P02538|K2C6A_HUMAN" 2 1446.7678 999 65569 13712 2 1446.765454 724.3912 "Keratin, type II cytoskeletal 6C OS=Homo sapiens OX=9606 GN=KRT6C PE=1 SV=3" 8.8 2546.4 - 9.31E+06 - - - -1.6368 - 2.623 0.407 - 553.1 1 2 0 -0.0024 17 0 0 0 7.96E+07 0.00E+00 - - - 4.4172 0.9992 221125_WJC_METTL3_EV_vs_WT_F05.13713.13713.3 2.12E-06 Dec-60 R.VFDKEGNGTVMGAELR.H "sp|P08590|MYL3_HUMAN,sp|P05976|MYL1_HUMAN,sp|P60660|MYL6_HUMAN,tr|F8W1R7|F8W1R7_HUMAN,tr|G3V1V0|G3V1V0_HUMAN,tr|B7Z6Z4|B7Z6Z4_HUMAN,tr|F8VZU9|F8VZU9_HUMAN,tr|G8JLA2|G8JLA2_HUMAN,tr|H0YI43|H0YI43_HUMAN,tr|F8W180|F8W180_HUMAN,tr|G3V1Y7|G3V1Y7_HUMAN,tr|J3KND3|J3KND3_HUMAN,tr|F8VPF3|F8VPF3_HUMAN" 13 1721.8407 1.14 65570 13713 3 1721.834539 574.9542 Myosin light chain 3 OS=Homo sapiens OX=9606 GN=MYL3 PE=1 SV=3 4.68 2546.5 - 2.99E+06 - - - -3.5607 - 2.599 0.493 - 170.3 1 2 1 -0.0061 16 0 0 0 2.82E+07 2.48E+07 - - - 6.4855 1 221125_WJC_METTL3_EV_vs_WT_F05.13717.13717.2 9.08E-08 20/24 L.LSSAVDHGSDEVK[136.11].F "sp|P78371|TCPB_HUMAN,tr|F8VQ14|F8VQ14_HUMAN,tr|F5GWF6|F5GWF6_HUMAN" 3 1350.6507 0.44 65574 13717 2 1350.650537 676.3326 T-complex protein 1 subunit beta OS=Homo sapiens OX=9606 GN=CCT2 PE=1 SV=4 4.54 2546.9 - 896888 - - - -0.1014 - 3.276 0.645 - 1411.1 1 1 0 -0.0001 13 0 0 0 3.48E+06 7.91E+06 - - - 6.8504 0.9966 221125_WJC_METTL3_EV_vs_WT_F05.13720.13720.2 3.54E-05 20-Dec K.MK[136.11]EIAEAYLGK[136.11].T "sp|P11142|HSP7C_HUMAN,tr|E9PQQ4|E9PQQ4_HUMAN,tr|E9PKE3|E9PKE3_HUMAN,tr|E9PN89|E9PN89_HUMAN,tr|E9PLF4|E9PLF4_HUMAN,tr|E9PI65|E9PI65_HUMAN,tr|E9PK54|E9PK54_HUMAN,tr|E9PPY6|E9PPY6_HUMAN,tr|E9PQK7|E9PQK7_HUMAN" 9 1267.6817 0.1 65577 13720 2 1267.68469 634.8481 Heat shock cognate 71 kDa protein OS=Homo sapiens OX=9606 GN=HSPA8 PE=1 SV=1 5.9 2547.3 - 740390 - - - 2.3507 - 2.564 0.483 - 316.1 1 2 1 0.003 11 0 0 0 1.43E+06 1.50E+07 - - - 5.1547 0.9995 221125_WJC_METTL3_EV_vs_WT_F05.13721.13721.2 0.032 18-Oct R.RKPFYPALIR.Y "sp|O00746|NDKM_HUMAN,tr|Q4TT34|Q4TT34_HUMAN,tr|H0Y6J0|H0Y6J0_HUMAN,tr|F2Z2X0|F2Z2X0_HUMAN,tr|A2IDC9|A2IDC9_HUMAN" 5 1259.7503 2.49 65578 13721 2 1259.75073 630.8824 "Nucleoside diphosphate kinase, mitochondrial OS=Homo sapiens OX=9606 GN=NME4 PE=1 SV=1" 11 2547.4 - 589952 - - - 0.3715 - 1.728 0.331 - 142.2 1 2 0 0.0005 10 0 0 0 1.77E+07 7.13E+06 - - - 3.0124 1 221125_WJC_METTL3_EV_vs_WT_F05.13724.13724.2 3.15E-09 14/28 K.DSALVEESNGTLEEK[136.11].Q sp|Q9UJA5|TRM6_HUMAN 1 1627.7668 0.43 65581 13724 2 1627.767405 814.8907 tRNA (adenine(58)-N(1))-methyltransferase non-catalytic subunit TRM6 OS=Homo sapiens OX=9606 GN=TRMT6 PE=1 SV=1 3.91 2547.8 - 334191 - - - 0.3557 - 2.652 0.654 - 540.2 1 2 0 0.0006 15 0 0 0 1.10E+06 2.53E+06 - - - 6.2691 1 221125_WJC_METTL3_EV_vs_WT_F05.13727.13727.2 8.73E-09 19/22 L.SSAVDHGSDEVK[136.11].F "sp|P78371|TCPB_HUMAN,tr|F8VQ14|F8VQ14_HUMAN,tr|F5GWF6|F5GWF6_HUMAN" 3 1237.5666 0.52 65583 13727 2 1237.570096 619.7906 T-complex protein 1 subunit beta OS=Homo sapiens OX=9606 GN=CCT2 PE=1 SV=4 4.53 2548.1 - 1.02E+06 - - - 2.8168 - 3.53 0.677 - 1439.7 1 1 0 0.0035 12 0 0 0 5.17E+06 9.94E+06 - - - 7.3589 0.9999 221125_WJC_METTL3_EV_vs_WT_F05.13731.13731.3 0.00139 16/40 R.EQLQLLEEQHR.A "sp|Q15149|PLEC_HUMAN,tr|H0YDN1|H0YDN1_HUMAN" 2 1421.7263 1.05 65586 13731 3 1421.72597 474.916 Plectin OS=Homo sapiens OX=9606 GN=PLEC PE=1 SV=3 4.75 2548.5 - 1.40E+06 - - - -0.2265 - 2.569 0.401 - 612.7 1 2 0 -0.0003 11 0 0 0 9.95E+06 9.52E+06 - - - 5.691 1 221125_WJC_METTL3_EV_vs_WT_F05.13732.13732.3 2.15E-05 18/52 R.YASINAHLGIEQSR.R "sp|Q8N752|KC1AL_HUMAN,sp|P48729|KC1A_HUMAN,tr|H0Y9X2|H0Y9X2_HUMAN,tr|A0A590UJ43|A0A590UJ43_HUMAN,tr|D6REM4|D6REM4_HUMAN,tr|E7ETM0|E7ETM0_HUMAN,tr|U3KPX3|U3KPX3_HUMAN,tr|A0A5F9W493|A0A5F9W493_HUMAN,tr|U3KQK7|U3KQK7_HUMAN" 9 1557.79 1.15 65587 13732 3 1557.7892 520.2706 Casein kinase I isoform alpha-like OS=Homo sapiens OX=9606 GN=CSNK1A1L PE=2 SV=2 6.75 2548.6 - 887023 - - - -0.4847 - 2.37 0.521 - 282.9 1 2 0 -0.0008 14 0 0 0 6.79E+06 5.91E+06 - - - 6.6416 0.9997 221125_WJC_METTL3_EV_vs_WT_F05.13734.13734.2 0.0312 22-Oct K.GQSSWGTGESFR[166.11].T sp|Q03252|LMNB2_HUMAN 1 1307.577 1.15 65589 13734 2 1307.575114 654.7958 Lamin-B2 OS=Homo sapiens OX=9606 GN=LMNB2 PE=1 SV=4 6 2548.9 - 660160 - - - -1.4408 - 2.163 0.421 - 307.8 1 2 0 -0.0019 12 0 0 0 1.82E+07 1.59E+07 - - - 4.1799 0.9987 221125_WJC_METTL3_EV_vs_WT_F05.13735.13735.3 0.0118 Jul-40 K.NFEHLNSDFDR.Y sp|P48163|MAOX_HUMAN 1 1392.6058 9.6 65590 13735 3 1392.603952 465.2092 NADP-dependent malic enzyme OS=Homo sapiens OX=9606 GN=ME1 PE=1 SV=1 4.54 2549 - 650442 - - - -1.3572 - 1.367 0.345 - 80.2 1 2 0 -0.0019 11 0 0 0 6.03E+06 6.28E+05 - - - 3.274 1 221125_WJC_METTL3_EV_vs_WT_F05.13736.13736.2 2.11E-06 13/22 K.GQSSWGTGESFR.T sp|Q03252|LMNB2_HUMAN 1 1297.5687 1.15 65591 13736 2 1297.568739 649.7916 Lamin-B2 OS=Homo sapiens OX=9606 GN=LMNB2 PE=1 SV=4 6 2549.2 - 601575 - - - 0.0085 - 2.502 0.602 - 727.3 1 2 0 0 12 0 0 0 1.82E+07 1.59E+07 - - - 5.9004 0.9999 221125_WJC_METTL3_EV_vs_WT_F05.13738.13738.3 1.81E-05 14/48 K.IEEVRDAMENEMR.T "sp|Q16891|MIC60_HUMAN,tr|B9A067|B9A067_HUMAN,tr|C9J406|C9J406_HUMAN,tr|H7C463|H7C463_HUMAN" 4 1620.7236 1.85 65593 13738 3 1620.723282 541.2485 MICOS complex subunit MIC60 OS=Homo sapiens OX=9606 GN=IMMT PE=1 SV=1 4.25 2549.4 - 298146 - - - -0.1907 - 2.585 0.571 - 346.6 1 2 1 -0.0003 13 0 0 0 7.54E+06 4.07E+06 - - - 7.481 0.9999 221125_WJC_METTL3_EV_vs_WT_F05.13743.13743.2 5.31E-05 17/18 K.K[136.11]SDVEAIFSK[136.11].Y "sp|P0DMR1|HNRC4_HUMAN,sp|P07910|HNRPC_HUMAN,sp|O60812|HNRC1_HUMAN,sp|B2RXH8|HNRC2_HUMAN,sp|B7ZW38|HNRC3_HUMAN,tr|G3V251|G3V251_HUMAN,tr|B4DY08|B4DY08_HUMAN,tr|G3V575|G3V575_HUMAN,tr|B4DSU6|B4DSU6_HUMAN,tr|G3V3K6|G3V3K6_HUMAN,tr|B2R5W2|B2R5W2_HUMAN,tr|G3V4C1|G3V4C1_HUMAN,tr|A0A0G2JPF8|A0A0G2JPF8_HUMAN,tr|A0A0G2JNQ3|A0A0G2JNQ3_HUMAN,tr|G3V576|G3V576_HUMAN,tr|G3V5X6|G3V5X6_HUMAN,tr|G3V2H6|G3V2H6_HUMAN,tr|G3V4W0|G3V4W0_HUMAN,tr|G3V555|G3V555_HUMAN,tr|G3V4M8|G3V4M8_HUMAN,tr|G3V2Q1|G3V2Q1_HUMAN" 21 1138.6205 1.4 65596 13743 2 1138.619821 570.3175 Heterogeneous nuclear ribonucleoprotein C-like 4 OS=Homo sapiens OX=9606 GN=HNRNPCL4 PE=3 SV=1 6.07 2550.1 - 1.56E+07 - - - -0.5876 - 3.102 0.458 - 941.7 1 2 0 -0.0007 10 0 0 0 3.26E+08 2.33E+08 - - - 5.5835 1 221125_WJC_METTL3_EV_vs_WT_F05.13744.13744.3 3.73E-06 17/60 R.EPSVPASC[160.03]AVSATYER[166.11].S "sp|Q92615|LAR4B_HUMAN,tr|H0Y641|H0Y641_HUMAN,tr|H0Y4V9|H0Y4V9_HUMAN" 3 1732.7966 1.16 65597 13744 3 1732.794656 578.6061 La-related protein 4B OS=Homo sapiens OX=9606 GN=LARP4B PE=1 SV=3 4.53 2550.2 - 1.19E+06 - - - -1.1046 - 2.519 0.515 - 174.9 1 2 0 -0.0019 16 0 0 0 2.50E+07 2.16E+07 - - - 6.6517 1 221125_WJC_METTL3_EV_vs_WT_F05.13745.13745.2 2.01E-10 13/28 K.ESC[160.03]DPSLGLAGPGAK.S "sp|O75410|TACC1_HUMAN,tr|E5RFM9|E5RFM9_HUMAN,tr|R4GMT7|R4GMT7_HUMAN,tr|E5RJG6|E5RJG6_HUMAN" 4 1457.682 2.64 65598 13745 2 1457.681912 729.8483 Transforming acidic coiled-coil-containing protein 1 OS=Homo sapiens OX=9606 GN=TACC1 PE=1 SV=2 4.37 2550.2 - 1.66E+06 - - - -0.0906 - 2.449 0.682 - 490.4 1 2 0 -0.0001 15 0 0 0 7.24E+07 2.75E+07 - - - 6.2803 0.8562 221125_WJC_METTL3_EV_vs_WT_F05.13746.13746.3 0.237 Jun-32 K.WDYEKNEWK.K sp|P13073|COX41_HUMAN 1 1296.5775 1.27 65599 13746 3 1296.577052 433.1998 "Cytochrome c oxidase subunit 4 isoform 1, mitochondrial OS=Homo sapiens OX=9606 GN=COX4I1 PE=1 SV=1" 4.68 2550.3 - 1.90E+06 - - - -0.3471 - 0.882 0.26 - 44.3 1 2 1 -0.0004 9 0 0 0 8.28E+06 6.49E+06 - - - 1.0602 0.9967 221125_WJC_METTL3_EV_vs_WT_F05.13747.13747.2 0.0351 20-Sep R.QQEQQVPILEK[136.11].F "sp|P49327|FAS_HUMAN,tr|A0A0U1RQF0|A0A0U1RQF0_HUMAN" 2 1346.7285 0.32 65600 13747 2 1346.730662 674.3715 Fatty acid synthase OS=Homo sapiens OX=9606 GN=FASN PE=1 SV=3 4.53 2550.4 - 472663 - - - 1.5831 - 1.57 0.217 - 291 1 2 0 0.0021 11 0 0 0 2.57E+06 8.04E+06 - - - 1.8634 0.9999 221125_WJC_METTL3_EV_vs_WT_F05.13752.13752.3 1.65E-05 19/64 K.MAPVPLDDSNRPASLTK.D "sp|Q9NYF8|BCLF1_HUMAN,tr|E9PKI6|E9PKI6_HUMAN,tr|A0A1W2PQ43|A0A1W2PQ43_HUMAN,tr|E9PK91|E9PK91_HUMAN,tr|E9PJA7|E9PJA7_HUMAN,tr|E9PK09|E9PK09_HUMAN,tr|E9PQN2|E9PQN2_HUMAN" 7 1810.9247 2.42 65604 13752 3 1810.922349 604.6489 Bcl-2-associated transcription factor 1 OS=Homo sapiens OX=9606 GN=BCLAF1 PE=1 SV=2 5.71 2551.2 - 1.32E+06 - - - -1.317 - 2.864 0.405 - 339.9 1 2 0 -0.0024 17 0 0 0 1.21E+10 4.98E+09 - - - 5.7129 0.9991 221125_WJC_METTL3_EV_vs_WT_F05.13753.13753.3 0.0639 Dec-48 K.IEEVR[166.11]DAMENEMR[166.11].T "sp|Q16891|MIC60_HUMAN,tr|B9A067|B9A067_HUMAN,tr|C9J406|C9J406_HUMAN,tr|H7C463|H7C463_HUMAN" 4 1640.7401 1.91 65605 13753 3 1640.738195 547.9207 MICOS complex subunit MIC60 OS=Homo sapiens OX=9606 GN=IMMT PE=1 SV=1 4.25 2551.3 - 465684 - - - -1.18 - 2.266 0.348 - 271.7 1 2 1 -0.0019 13 0 0 0 7.77E+06 4.07E+06 - - - 4.6372 1 221125_WJC_METTL3_EV_vs_WT_F05.13755.13755.3 4.28E-09 18/40 R.LVNHFVEEFKR.K "sp|P0DMV8|HS71A_HUMAN,sp|P0DMV9|HS71B_HUMAN,tr|V9GZ37|V9GZ37_HUMAN,tr|A0A0G2JIW1|A0A0G2JIW1_HUMAN" 4 1416.7514 0.13 65607 13755 3 1416.752047 473.2577 Heat shock 70 kDa protein 1A OS=Homo sapiens OX=9606 GN=HSPA1A PE=1 SV=1 6.76 2551.4 - 1.37E+06 - - - 0.468 - 2.823 0.558 - 575.8 1 2 0 0.0007 11 0 0 0 2.68E+08 1.99E+09 - - - 7.7092 0.9999 221125_WJC_METTL3_EV_vs_WT_F05.13756.13756.3 7.15E-05 Nov-48 K.VVQLHEYSEELEK.L "sp|Q14683|SMC1A_HUMAN,tr|G8JLG1|G8JLG1_HUMAN,tr|A0A6Q8PHC3|A0A6Q8PHC3_HUMAN" 3 1601.7937 1.1 65608 13756 3 1601.791532 534.9385 Structural maintenance of chromosomes protein 1A OS=Homo sapiens OX=9606 GN=SMC1A PE=1 SV=2 4.48 2551.5 - 807796 - - - -1.3554 - 2.168 0.438 - 126.6 1 2 0 -0.0022 13 0 0 0 3.76E+07 3.41E+07 - - - 5.5207 0.9999 221125_WJC_METTL3_EV_vs_WT_F05.13761.13761.3 0.000454 13/52 R.YASINAHLGIEQSR[166.11].R "sp|Q8N752|KC1AL_HUMAN,sp|P48729|KC1A_HUMAN,tr|H0Y9X2|H0Y9X2_HUMAN,tr|A0A590UJ43|A0A590UJ43_HUMAN,tr|D6REM4|D6REM4_HUMAN,tr|E7ETM0|E7ETM0_HUMAN,tr|U3KPX3|U3KPX3_HUMAN,tr|A0A5F9W493|A0A5F9W493_HUMAN,tr|U3KQK7|U3KQK7_HUMAN" 9 1567.7982 1.15 65613 13761 3 1567.797168 523.6067 Casein kinase I isoform alpha-like OS=Homo sapiens OX=9606 GN=CSNK1A1L PE=2 SV=2 6.75 2552.1 - 493679 - - - -0.6742 - 2.339 0.376 - 120.3 1 2 0 -0.0011 14 0 0 0 6.79E+06 5.91E+06 - - - 4.9899 0.9984 221125_WJC_METTL3_EV_vs_WT_F05.13764.13764.3 0.129 Oct-40 K.SELFSGLPQKK.L "sp|Q5T160|SYRM_HUMAN,tr|H0Y450|H0Y450_HUMAN" 2 1232.6765 1.34 65616 13764 3 1232.677162 411.8994 "Probable arginine--tRNA ligase, mitochondrial OS=Homo sapiens OX=9606 GN=RARS2 PE=1 SV=1" 8.31 2552.5 - 460487 - - - 0.5468 - 1.614 0.275 - 101.4 1 2 0 0.0007 11 0 0 0 5.59E+06 4.17E+06 - - - 2.9657 0.9999 221125_WJC_METTL3_EV_vs_WT_F05.13769.13769.2 0.000211 20-Nov K.LSAMMGAVAEK[136.11].K "sp|Q86U44|MTA70_HUMAN,tr|F5H6D8|F5H6D8_HUMAN,tr|H0YFV6|H0YFV6_HUMAN,tr|B4DTN4|B4DTN4_HUMAN" 4 1114.5606 0.51 65619 13769 2 1114.560431 558.2876 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 6 2553.2 - 1.14E+07 - - - -0.1534 - 2.276 0.453 - 392.8 1 2 0 -0.0002 11 0 0 0 9.11E+07 1.77E+08 - - - 4.6116 0.9991 221125_WJC_METTL3_EV_vs_WT_F05.13770.13770.3 0.000658 Sep-48 K.FVSEDDR[166.11]NSFTLK[136.11].L "sp|P34932|HSP74_HUMAN,tr|A0A087WYC1|A0A087WYC1_HUMAN" 2 1574.7696 0.07 65620 13770 3 1574.769251 525.9305 Heat shock 70 kDa protein 4 OS=Homo sapiens OX=9606 GN=HSPA4 PE=1 SV=4 4.56 2553.2 - 5.16E+06 - - - -0.1943 - 1.93 0.378 - 60.2 1 2 1 -0.0003 13 0 0 0 5.36E+06 7.50E+07 - - - 4.537 1 221125_WJC_METTL3_EV_vs_WT_F05.13772.13772.3 3.28E-07 15/48 K.VVQLHEYSEELEK[136.11].L "sp|Q14683|SMC1A_HUMAN,tr|G8JLG1|G8JLG1_HUMAN,tr|A0A6Q8PHC3|A0A6Q8PHC3_HUMAN" 3 1609.8079 1.07 65622 13772 3 1609.807069 537.6099 Structural maintenance of chromosomes protein 1A OS=Homo sapiens OX=9606 GN=SMC1A PE=1 SV=2 4.48 2553.3 - 2.20E+06 - - - -0.5181 - 2.57 0.539 - 302.3 1 2 0 -0.0008 13 0 0 0 3.66E+07 3.41E+07 - - - 7.1083 0.9956 221125_WJC_METTL3_EV_vs_WT_F05.13773.13773.3 0.0122 Nov-44 K.ER[166.11]EVLQLQEEVK[136.11].N sp|Q9BYN8|RT26_HUMAN 1 1516.8216 2 65623 13773 3 1516.819216 506.6145 "28S ribosomal protein S26, mitochondrial OS=Homo sapiens OX=9606 GN=MRPS26 PE=1 SV=1" 4.49 2553.4 - 1.80E+06 - - - -1.5664 - 2.447 0.227 - 236.1 1 2 1 -0.0024 12 0 0 0 3.51E+07 1.75E+07 - - - 3.5506 0.9867 221125_WJC_METTL3_EV_vs_WT_F05.13774.13774.3 0.054 Jul-60 R.EPSVPASC[160.03]AVSATYER.S "sp|Q92615|LAR4B_HUMAN,tr|H0Y641|H0Y641_HUMAN,tr|H0Y4V9|H0Y4V9_HUMAN" 3 1722.7883 1.15 65624 13774 3 1722.784522 575.27 La-related protein 4B OS=Homo sapiens OX=9606 GN=LARP4B PE=1 SV=3 4.53 2553.4 - 1.38E+06 - - - -2.193 - 1.478 0.227 - 60.1 1 2 0 -0.0038 16 0 0 0 2.55E+07 2.22E+07 - - - 2.0722 0.9842 221125_WJC_METTL3_EV_vs_WT_F05.13775.13775.3 0.00755 Sep-40 K.DFK[136.11]ENNVVFNR[166.11].F "sp|O43615|TIM44_HUMAN,tr|M0QXU7|M0QXU7_HUMAN" 2 1398.7011 0.95 65625 13775 3 1398.700203 467.241 Mitochondrial import inner membrane translocase subunit TIM44 OS=Homo sapiens OX=9606 GN=TIMM44 PE=1 SV=2 6.07 2553.5 - 1.15E+06 - - - -0.6292 - 1.559 0.239 - 124.3 1 2 1 -0.0009 11 0 0 0 4.68E+07 4.91E+07 - - - 2.4658 0.9988 221125_WJC_METTL3_EV_vs_WT_F05.13776.13776.3 3.11E-06 15/32 V.NHFVEEFK[136.11]R[166.11].K "sp|P0DMV8|HS71A_HUMAN,sp|P0DMV9|HS71B_HUMAN,tr|V9GZ37|V9GZ37_HUMAN,tr|A0A0G2JIW1|A0A0G2JIW1_HUMAN" 4 1222.6214 0.46 65626 13776 3 1222.620693 408.5477 Heat shock 70 kDa protein 1A OS=Homo sapiens OX=9606 GN=HSPA1A PE=1 SV=1 6.76 2553.7 - 760693 - - - -0.5586 - 2.851 0.567 - 488.2 1 1 0 -0.0007 9 0 0 0 1.72E+07 3.77E+07 - - - 8.0188 0.9999 221125_WJC_METTL3_EV_vs_WT_F05.13778.13778.2 7.76E-07 22-Oct K.NETDEDGWTTVR.R sp|Q14152|EIF3A_HUMAN 1 1421.6059 1.36 65628 13778 2 1421.606747 711.8102 Eukaryotic translation initiation factor 3 subunit A OS=Homo sapiens OX=9606 GN=EIF3A PE=1 SV=1 3.92 2553.9 - 296384 - - - 0.5944 - 2.087 0.586 - 392.3 1 2 0 0.0008 12 0 0 0 3.88E+06 2.85E+06 - - - 5.3048 0.9998 221125_WJC_METTL3_EV_vs_WT_F05.13782.13782.3 0.00125 14/44 K.EREVLQLQEEVK.N sp|Q9BYN8|RT26_HUMAN 1 1498.7991 1.98 65630 13782 3 1498.798797 500.607 "28S ribosomal protein S26, mitochondrial OS=Homo sapiens OX=9606 GN=MRPS26 PE=1 SV=1" 4.49 2554.5 - 3.46E+06 - - - -0.2168 - 2.707 0.405 - 422.6 1 2 1 -0.0003 12 0 0 0 3.47E+07 1.75E+07 - - - 5.8156 1 221125_WJC_METTL3_EV_vs_WT_F05.13783.13783.3 6.94E-09 14/52 R.STAYEDYYYHPPPR.M "sp|O43390|HNRPR_HUMAN,tr|B4DT28|B4DT28_HUMAN,tr|A0A6Q8PH35|A0A6Q8PH35_HUMAN,tr|A0A286YEZ8|A0A286YEZ8_HUMAN" 4 1757.7686 1.37 65631 13783 3 1757.768477 586.9301 Heterogeneous nuclear ribonucleoprotein R OS=Homo sapiens OX=9606 GN=HNRNPR PE=1 SV=1 5.3 2554.5 - 2.18E+06 - - - -0.0415 - 2.698 0.611 - 223.2 1 2 0 -0.0001 14 0 0 0 1.65E+08 1.20E+08 - - - 7.9897 0.9932 221125_WJC_METTL3_EV_vs_WT_F05.13784.13784.3 0.0172 Sep-40 K.DFKENNVVFNR.F "sp|O43615|TIM44_HUMAN,tr|M0QXU7|M0QXU7_HUMAN" 2 1380.6786 0.95 65632 13784 3 1380.677638 461.2335 Mitochondrial import inner membrane translocase subunit TIM44 OS=Homo sapiens OX=9606 GN=TIMM44 PE=1 SV=2 6.07 2554.6 - 1.57E+06 - - - -0.7062 - 1.778 0.256 - 132.4 1 2 1 -0.001 11 0 0 0 4.67E+07 4.90E+07 - - - 3.0287 1 221125_WJC_METTL3_EV_vs_WT_F05.13786.13786.3 0.000695 14/44 R.TFIAIK[136.11]PDGVQR[166.11].G "sp|P15531|NDKA_HUMAN,sp|P22392|NDKB_HUMAN,tr|Q32Q12|Q32Q12_HUMAN,tr|Q32Q12|Q32Q12_HUMAN,tr|J3KPD9|J3KPD9_HUMAN,tr|F6XY72|F6XY72_HUMAN,tr|E5RHP0|E5RHP0_HUMAN,tr|E7ERL0|E7ERL0_HUMAN,tr|C9K028|C9K028_HUMAN" 9 1361.7786 1.41 65634 13786 3 1361.778478 454.9335 Nucleoside diphosphate kinase A OS=Homo sapiens OX=9606 GN=NME1 PE=1 SV=1 8.41 2554.7 - 970548 - - - -0.0933 - 2.48 0.456 - 248.7 1 2 0 -0.0001 12 0 0 0 8.84E+07 6.28E+07 - - - 6.1415 1 221125_WJC_METTL3_EV_vs_WT_F05.13788.13788.3 1.68E-12 20/60 K.MEDSVGC[160.03]LETAEEVK[136.11]R[166.11].K sp|P35579|MYH9_HUMAN 1 1869.8567 1.25 65636 13788 3 1869.854267 624.2929 Myosin-9 OS=Homo sapiens OX=9606 GN=MYH9 PE=1 SV=4 4.25 2555 - 814080 - - - -1.3194 - 3.506 0.711 - 782.7 1 2 0 -0.0025 16 0 0 0 1.69E+07 1.35E+07 - - - 9.6851 0.9999 221125_WJC_METTL3_EV_vs_WT_F05.13789.13789.3 0.0235 16/48 K.IDYGEYMDK[136.11]NNVR[166.11].R "sp|Q04837|SSBP_HUMAN,tr|A0A0G2JLD8|A0A0G2JLD8_HUMAN,tr|E7EUY5|E7EUY5_HUMAN" 3 1633.7525 1.31 65637 13789 3 1633.751915 545.5915 "Single-stranded DNA-binding protein, mitochondrial OS=Homo sapiens OX=9606 GN=SSBP1 PE=1 SV=1" 4.56 2555.1 - 739080 - - - -0.374 - 2.597 0.493 - 275.3 1 2 1 -0.0006 13 0 0 0 4.61E+07 3.52E+07 - - - 6.6238 1 221125_WJC_METTL3_EV_vs_WT_F05.13790.13790.3 4.75E-09 20/60 K.MEDSVGC[160.03]LETAEEVKR.K sp|P35579|MYH9_HUMAN 1 1851.8343 1.25 65638 13790 3 1851.831962 618.2854 Myosin-9 OS=Homo sapiens OX=9606 GN=MYH9 PE=1 SV=4 4.25 2555.2 - 692961 - - - -1.2431 - 3.649 0.663 - 789.1 1 2 0 -0.0023 16 0 0 0 1.69E+07 1.35E+07 - - - 9.2525 0.9999 221125_WJC_METTL3_EV_vs_WT_F05.13792.13792.3 9.78E-07 17/48 K.TELISVSEVHPSR[166.11].L "sp|P42224|STAT1_HUMAN,tr|A0A669KB68|A0A669KB68_HUMAN,tr|A0A669KBA4|A0A669KBA4_HUMAN,tr|A0A669KB56|A0A669KB56_HUMAN,tr|A0A669KB53|A0A669KB53_HUMAN" 5 1462.7655 4.59 65640 13792 3 1462.768878 488.5958 Signal transducer and activator of transcription 1-alpha\beta OS=Homo sapiens OX=9606 GN=STAT1 PE=1 SV=2 5.37 2555.5 - 344324 - - - 2.2909 - 2.82 0.473 - 483.7 1 2 0 0.0034 13 0 0 0 2.77E+07 6.04E+06 - - - 6.6234 0.9982 221125_WJC_METTL3_EV_vs_WT_F05.13794.13794.2 9.85E-06 14/22 K.EREVLQLQEEVK.N sp|Q9BYN8|RT26_HUMAN 1 1498.7991 2.46 65642 13794 2 1498.798769 750.4068 "28S ribosomal protein S26, mitochondrial OS=Homo sapiens OX=9606 GN=MRPS26 PE=1 SV=1" 4.49 2555.8 - 324964 - - - -0.2355 - 2.956 0.333 - 530.5 1 2 1 -0.0004 12 0 0 0 4.85E+06 1.97E+06 - - - 4.3522 1 221125_WJC_METTL3_EV_vs_WT_F05.13800.13800.2 4.36E-05 14/20 R.LVNHFVEEFK[136.11]R[166.11].K "sp|P0DMV8|HS71A_HUMAN,sp|P0DMV9|HS71B_HUMAN,tr|V9GZ37|V9GZ37_HUMAN,tr|A0A0G2JIW1|A0A0G2JIW1_HUMAN" 4 1434.7739 0.14 65646 13800 2 1434.773867 718.3942 Heat shock 70 kDa protein 1A OS=Homo sapiens OX=9606 GN=HSPA1A PE=1 SV=1 6.76 2556.5 - 2.13E+06 - - - 0.0091 - 2.556 0.585 - 963 1 2 0 0 11 0 0 0 1.22E+07 8.93E+07 - - - 5.9005 1 221125_WJC_METTL3_EV_vs_WT_F05.13801.13801.3 0.000585 13/44 R.TFIAIKPDGVQR.G "sp|P15531|NDKA_HUMAN,sp|P22392|NDKB_HUMAN,tr|Q32Q12|Q32Q12_HUMAN,tr|Q32Q12|Q32Q12_HUMAN,tr|J3KPD9|J3KPD9_HUMAN,tr|F6XY72|F6XY72_HUMAN,tr|E5RHP0|E5RHP0_HUMAN,tr|E7ERL0|E7ERL0_HUMAN,tr|C9K028|C9K028_HUMAN" 9 1343.7561 1.42 65647 13801 3 1343.755446 448.926 Nucleoside diphosphate kinase A OS=Homo sapiens OX=9606 GN=NME1 PE=1 SV=1 8.41 2556.5 - 3.09E+06 - - - -0.5127 - 2.45 0.534 - 181.1 1 2 0 -0.0007 12 0 0 0 8.89E+07 6.26E+07 - - - 6.9772 1 221125_WJC_METTL3_EV_vs_WT_F05.13803.13803.3 1.39E-08 19/52 R.GPTPFNQNQLHQLR.A "sp|P51532|SMCA4_HUMAN,tr|A0A2R8Y7S2|A0A2R8Y7S2_HUMAN,tr|Q9HBD4|Q9HBD4_HUMAN,tr|A0A2R8YGP5|A0A2R8YGP5_HUMAN,tr|A0A2R8Y4P4|A0A2R8Y4P4_HUMAN" 5 1648.8434 0.69 65649 13803 3 1648.845481 550.6217 Transcription activator BRG1 OS=Homo sapiens OX=9606 GN=SMARCA4 PE=1 SV=2 9.76 2556.8 - 991523 - - - 1.27 - 3.667 0.621 - 755.2 1 2 0 0.0021 14 0 0 0 2.03E+07 2.95E+07 - - - 8.9161 0.999 221125_WJC_METTL3_EV_vs_WT_F05.13806.13806.2 3.80E-07 20-Nov K.DFK[136.11]ENNVVFNR[166.11].F "sp|O43615|TIM44_HUMAN,tr|M0QXU7|M0QXU7_HUMAN" 2 1398.7011 0.26 65652 13806 2 1398.701042 700.3578 Mitochondrial import inner membrane translocase subunit TIM44 OS=Homo sapiens OX=9606 GN=TIMM44 PE=1 SV=2 6.07 2557.2 - 526095 - - - -0.0293 - 2.096 0.607 - 291.2 1 2 1 0 11 0 0 0 4.34E+06 1.67E+07 - - - 5.5262 0.9993 221125_WJC_METTL3_EV_vs_WT_F05.13807.13807.3 0.0498 Nov-36 R.GSGIQWDLR[166.11]K[136.11].T "sp|O75306|NDUS2_HUMAN,tr|A0A7I2V4X8|A0A7I2V4X8_HUMAN,tr|A0A7I2V4G5|A0A7I2V4G5_HUMAN,tr|A0A7I2YQG7|A0A7I2YQG7_HUMAN,tr|A0A7I2V596|A0A7I2V596_HUMAN,tr|A0A7I2V5G4|A0A7I2V5G4_HUMAN,tr|A0A7I2V410|A0A7I2V410_HUMAN,tr|A0A7I2V630|A0A7I2V630_HUMAN,tr|A0A7I2V2B9|A0A7I2V2B9_HUMAN,tr|A0A7I2YQD8|A0A7I2YQD8_HUMAN,tr|A0A7I2V3J6|A0A7I2V3J6_HUMAN,tr|A0A7I2V5E2|A0A7I2V5E2_HUMAN,tr|A0A7I2V4W5|A0A7I2V4W5_HUMAN" 13 1176.637 1.51 65653 13807 3 1176.635724 393.2196 "NADH dehydrogenase [ubiquinone] iron-sulfur protein 2, mitochondrial OS=Homo sapiens OX=9606 GN=NDUFS2 PE=1 SV=2" 8.75 2557.3 - 500138 - - - -1.1065 - 1.87 0.287 - 143.1 1 2 0 -0.0013 10 0 0 0 8.19E+06 5.42E+06 - - - 3.5674 0.9998 221125_WJC_METTL3_EV_vs_WT_F05.13808.13808.2 7.26E-06 20-Nov R.LVNHFVEEFKR.K "sp|P0DMV8|HS71A_HUMAN,sp|P0DMV9|HS71B_HUMAN,tr|V9GZ37|V9GZ37_HUMAN,tr|A0A0G2JIW1|A0A0G2JIW1_HUMAN" 4 1416.7514 0.14 65654 13808 2 1416.753542 709.383 Heat shock 70 kDa protein 1A OS=Homo sapiens OX=9606 GN=HSPA1A PE=1 SV=1 6.76 2557.4 - 335887 - - - 1.5232 - 2.427 0.512 - 417.7 1 2 0 0.0022 11 0 0 0 1.22E+07 8.92E+07 - - - 5.2206 0.9752 221125_WJC_METTL3_EV_vs_WT_F05.13810.13810.2 0.0232 24-Aug K.VVQLHEYSEELEK.L "sp|Q14683|SMC1A_HUMAN,tr|G8JLG1|G8JLG1_HUMAN,tr|A0A6Q8PHC3|A0A6Q8PHC3_HUMAN" 3 1601.7937 0.77 65656 13810 2 1601.804984 801.9041 Structural maintenance of chromosomes protein 1A OS=Homo sapiens OX=9606 GN=SMC1A PE=1 SV=2 4.48 2557.7 - 271497 - - - 7.0427 - 1.892 0.367 - 178.2 1 2 0 0.0113 13 0 0 0 1.52E+06 1.97E+06 - - - 3.3846 1 221125_WJC_METTL3_EV_vs_WT_F05.13811.13811.2 7.71E-08 15/24 K.VVQLHEYSEELEK[136.11].L "sp|Q14683|SMC1A_HUMAN,tr|G8JLG1|G8JLG1_HUMAN,tr|A0A6Q8PHC3|A0A6Q8PHC3_HUMAN" 3 1609.8079 0.77 65657 13811 2 1609.803637 805.9112 Structural maintenance of chromosomes protein 1A OS=Homo sapiens OX=9606 GN=SMC1A PE=1 SV=2 4.48 2557.8 - 212750 - - - -2.65 - 2.88 0.609 - 812.2 1 2 0 -0.0043 13 0 0 0 1.52E+06 1.97E+06 - - - 6.2526 1 221125_WJC_METTL3_EV_vs_WT_F05.13815.13815.3 6.12E-06 Oct-40 K.HIYFINC[160.03]GDSR[166.11].A "sp|O75688|PPM1B_HUMAN,tr|B8ZZF0|B8ZZF0_HUMAN,tr|A0A3B3IS24|A0A3B3IS24_HUMAN,tr|C9JIR6|C9JIR6_HUMAN" 4 1390.6327 2.91 65659 13815 3 1390.632864 464.5515 Protein phosphatase 1B OS=Homo sapiens OX=9606 GN=PPM1B PE=1 SV=1 6.73 2558.3 - 3.04E+06 - - - 0.0899 - 1.836 0.565 - 179.4 1 2 0 0.0001 11 0 0 0 5.56E+08 1.91E+08 - - - 6.5652 0.8603 221125_WJC_METTL3_EV_vs_WT_F05.13816.13816.3 0.0341 Aug-36 K.LKEENFFNPK.E "sp|Q9Y6M1|IF2B2_HUMAN,tr|F8W930|F8W930_HUMAN" 2 1264.6452 1.76 65660 13816 3 1264.64528 422.5557 Insulin-like growth factor 2 mRNA-binding protein 2 OS=Homo sapiens OX=9606 GN=IGF2BP2 PE=1 SV=2 6.14 2558.3 - 8.10E+06 - - - 0.0727 - 1.398 0.14 - 77.1 1 2 1 0.0001 10 0 0 0 4.12E+07 2.35E+07 - - - 1.0793 1 221125_WJC_METTL3_EV_vs_WT_F05.13817.13817.2 5.17E-08 13/22 R.FLEQQNQVLQTK.W "sp|Q7Z794|K2C1B_HUMAN,sp|P04264|K2C1_HUMAN,sp|P35908|K22E_HUMAN" 3 1474.778 999 65661 13817 2 1474.778358 738.3963 "Keratin, type II cytoskeletal 1b OS=Homo sapiens OX=9606 GN=KRT77 PE=1 SV=3" 6 2558.4 - 1.03E+06 - - - 0.2475 - 2.801 0.568 - 551.5 1 2 0 0.0004 12 0 0 0 3.84E+08 0.00E+00 - - - 5.9462 0.9999 221125_WJC_METTL3_EV_vs_WT_F05.13818.13818.2 1.08E-07 20-Nov K.HIYFINC[160.03]GDSR[166.11].A "sp|O75688|PPM1B_HUMAN,tr|B8ZZF0|B8ZZF0_HUMAN,tr|A0A3B3IS24|A0A3B3IS24_HUMAN,tr|C9JIR6|C9JIR6_HUMAN" 4 1390.6327 2.98 65662 13818 2 1390.631556 696.3236 Protein phosphatase 1B OS=Homo sapiens OX=9606 GN=PPM1B PE=1 SV=1 6.73 2558.6 - 761208 - - - -0.8507 - 2.151 0.606 - 364.8 1 2 0 -0.0012 11 0 0 0 1.54E+08 5.17E+07 - - - 5.5886 0.9999 221125_WJC_METTL3_EV_vs_WT_F05.13824.13824.3 2.10E-05 14/48 K.VSRPLELC[160.03]YAPTK.D sp|Q06587|RING1_HUMAN 1 1532.8021 2.5 65668 13824 3 1532.801365 511.9413 E3 ubiquitin-protein ligase RING1 OS=Homo sapiens OX=9606 GN=RING1 PE=1 SV=2 8.17 2559.4 - 381942 - - - -0.4789 - 2.435 0.402 - 211.2 1 2 0 -0.0007 13 0 0 0 4.05E+06 1.62E+06 - - - 5.4346 1 221125_WJC_METTL3_EV_vs_WT_F05.13828.13828.3 6.17E-06 Nov-40 K.HIYFINC[160.03]GDSR.A "sp|O75688|PPM1B_HUMAN,tr|B8ZZF0|B8ZZF0_HUMAN,tr|A0A3B3IS24|A0A3B3IS24_HUMAN,tr|C9JIR6|C9JIR6_HUMAN" 4 1380.6245 2.91 65670 13828 3 1380.624319 461.2154 Protein phosphatase 1B OS=Homo sapiens OX=9606 GN=PPM1B PE=1 SV=1 6.73 2559.9 - 1.68E+07 - - - -0.1086 - 1.99 0.563 - 241.4 1 2 0 -0.0001 11 0 0 0 5.56E+08 1.91E+08 - - - 6.7717 0.9996 221125_WJC_METTL3_EV_vs_WT_F05.13829.13829.3 0.000768 Dec-40 R.EIAQDFKTDLR.F "sp|Q16695|H31T_HUMAN,sp|P84243|H33_HUMAN,sp|Q71DI3|H32_HUMAN,sp|P68431|H31_HUMAN,tr|B4DEB1|B4DEB1_HUMAN,tr|K7EK07|K7EK07_HUMAN,tr|K7ES00|K7ES00_HUMAN,tr|K7EMV3|K7EMV3_HUMAN,tr|A0A590UJJ6|A0A590UJJ6_HUMAN" 9 1334.683 1.13 65671 13829 3 1334.681893 445.9016 Histone H3.1t OS=Homo sapiens OX=9606 GN=H3-4 PE=1 SV=3 4.56 2559.9 - 4.03E+06 - - - -0.8519 - 2.044 0.434 - 210.4 1 2 1 -0.0011 11 0 0 0 4.81E+07 4.24E+07 - - - 5.4093 0.9997 221125_WJC_METTL3_EV_vs_WT_F05.13833.13833.3 0.0016 Sep-40 R.AQHLADILSSK.G "sp|Q9UHI6|DDX20_HUMAN,tr|A0A7P0T8G7|A0A7P0T8G7_HUMAN,tr|A0A7P0TB94|A0A7P0TB94_HUMAN,tr|A0A7P0T9T8|A0A7P0T9T8_HUMAN" 4 1181.6404 1.25 65675 13833 3 1181.63913 394.8874 Probable ATP-dependent RNA helicase DDX20 OS=Homo sapiens OX=9606 GN=DDX20 PE=1 SV=2 6.79 2560.3 - 545584 - - - -1.1061 - 1.711 0.385 - 74.7 1 2 0 -0.0013 11 0 0 0 1.74E+07 1.39E+07 - - - 4.3578 0.9999 221125_WJC_METTL3_EV_vs_WT_F05.13836.13836.3 0.025 15/40 R.AQHLADILSSK[136.11].G "sp|Q9UHI6|DDX20_HUMAN,tr|A0A7P0T8G7|A0A7P0T8G7_HUMAN,tr|A0A7P0TB94|A0A7P0TB94_HUMAN,tr|A0A7P0T9T8|A0A7P0T9T8_HUMAN" 4 1189.6546 1.25 65678 13836 3 1189.653264 397.5588 Probable ATP-dependent RNA helicase DDX20 OS=Homo sapiens OX=9606 GN=DDX20 PE=1 SV=2 6.79 2560.7 - 411464 - - - -1.1541 - 2.664 0.368 - 258.2 1 2 0 -0.0014 11 0 0 0 1.74E+07 1.39E+07 - - - 5.426 0.9799 221125_WJC_METTL3_EV_vs_WT_F05.13837.13837.3 0.0798 Aug-32 K.FRFDYTNER.A "sp|P24928|RPB1_HUMAN,tr|A0A6Q8PGB0|A0A6Q8PGB0_HUMAN" 2 1246.5731 1.06 65679 13837 3 1246.573413 416.5316 DNA-directed RNA polymerase II subunit RPB1 OS=Homo sapiens OX=9606 GN=POLR2A PE=1 SV=2 6.07 2560.8 - 410342 - - - 0.2631 - 1.525 0.224 - 125.4 1 2 1 0.0003 9 0 0 0 7.42E+06 6.97E+06 - - - 2.3091 0.9999 221125_WJC_METTL3_EV_vs_WT_F05.13838.13838.2 0.0383 22-Dec R.TFIAIK[136.11]PDGVQR[166.11].G "sp|P15531|NDKA_HUMAN,sp|P22392|NDKB_HUMAN,tr|Q32Q12|Q32Q12_HUMAN,tr|Q32Q12|Q32Q12_HUMAN,tr|J3KPD9|J3KPD9_HUMAN,tr|F6XY72|F6XY72_HUMAN,tr|E5RHP0|E5RHP0_HUMAN,tr|E7ERL0|E7ERL0_HUMAN,tr|C9K028|C9K028_HUMAN" 9 1361.7786 1.65 65680 13838 2 1361.779362 681.8966 Nucleoside diphosphate kinase A OS=Homo sapiens OX=9606 GN=NME1 PE=1 SV=1 8.41 2561 - 403046 - - - 0.5559 - 2.589 0.472 - 497.9 1 2 0 0.0008 12 0 0 0 6.29E+06 3.80E+06 - - - 5.0299 0.9997 221125_WJC_METTL3_EV_vs_WT_F05.13842.13842.2 0.000107 22-Oct K.QLQQELQEYQNK.L "sp|Q9NZM3|ITSN2_HUMAN,tr|A0A087WVF7|A0A087WVF7_HUMAN,tr|E7EPJ2|E7EPJ2_HUMAN" 3 1547.758 5.94 65684 13842 2 1547.760937 774.8863 Intersectin-2 OS=Homo sapiens OX=9606 GN=ITSN2 PE=1 SV=3 4.53 2561.5 - 293524 - - - 1.9066 - 2.264 0.491 - 429.2 1 2 0 0.003 12 0 0 0 3.03E+06 5.10E+05 - - - 4.8166 0.9995 221125_WJC_METTL3_EV_vs_WT_F05.13848.13848.3 0.000221 Dec-36 K.LK[136.11]EENFFNPK[136.11].E "sp|Q9Y6M1|IF2B2_HUMAN,tr|F8W930|F8W930_HUMAN" 2 1280.6736 1.76 65688 13848 3 1280.672035 427.8985 Insulin-like growth factor 2 mRNA-binding protein 2 OS=Homo sapiens OX=9606 GN=IGF2BP2 PE=1 SV=2 6.14 2562.2 - 1.84E+06 - - - -1.2126 - 1.946 0.417 - 151.1 1 2 1 -0.0016 10 0 0 0 4.11E+07 2.34E+07 - - - 5.1331 0.9957 221125_WJC_METTL3_EV_vs_WT_F05.13849.13849.2 2.49E-06 24-Nov R.NEQDAYAINSYTR[166.11].S "sp|P24752|THIL_HUMAN,tr|A0A5F9ZHJ7|A0A5F9ZHJ7_HUMAN,tr|A0A5F9ZHD4|A0A5F9ZHD4_HUMAN,tr|A0A5F9ZHJ0|A0A5F9ZHJ0_HUMAN,tr|A0A5F9ZHL1|A0A5F9ZHL1_HUMAN,tr|A0A5F9ZI66|A0A5F9ZI66_HUMAN" 6 1553.6986 1.24 65689 13849 2 1554.701552 777.8566 "Acetyl-CoA acetyltransferase, mitochondrial OS=Homo sapiens OX=9606 GN=ACAT1 PE=1 SV=1" 4.37 2562.4 - 770236 - - - 645.5448 - 2.211 0.588 - 325.6 1 2 0 1.003 13 0 0 0 1.68E+08 1.36E+08 - - - 5.1054 0.9991 221125_WJC_METTL3_EV_vs_WT_F05.13850.13850.3 0.00176 Nov-64 R.VNSLAPGPISGTEGLRR.L "sp|Q9NUI1|DECR2_HUMAN,tr|A0A0J9YWI0|A0A0J9YWI0_HUMAN,tr|Q4VXZ8|Q4VXZ8_HUMAN" 3 1722.9377 1.08 65690 13850 3 1722.937365 575.3198 "Peroxisomal 2,4-dienoyl-CoA reductase [(3E)-enoyl-CoA-producing] OS=Homo sapiens OX=9606 GN=DECR2 PE=1 SV=1" 9.57 2562.5 - 764911 - - - -0.184 - 2.321 0.257 - 92 2 2 0 -0.0003 17 0 0 0 6.30E+06 5.81E+06 - - - 3.393 0.9999 221125_WJC_METTL3_EV_vs_WT_F05.13851.13851.3 1.40E-05 13/44 K.R[166.11]VEDLQTQDFVR[166.11].S sp|P0C7T5|ATX1L_HUMAN 1 1524.7799 4.93 65691 13851 3 1524.777111 509.2673 Ataxin-1-like OS=Homo sapiens OX=9606 GN=ATXN1L PE=1 SV=1 4.56 2562.6 - 716256 - - - -1.8593 - 2.416 0.486 - 269.5 1 2 0 -0.0028 12 0 0 0 4.17E+07 8.45E+06 - - - 6.4027 1 221125_WJC_METTL3_EV_vs_WT_F05.13855.13855.2 3.54E-06 24-Nov K.C[160.03]DNC[160.03]GIEPIQGVR.W sp|Q8IYH5|ZZZ3_HUMAN 1 1516.6762 1.61 65695 13855 2 1516.674588 759.3454 ZZ-type zinc finger-containing protein 3 OS=Homo sapiens OX=9606 GN=ZZZ3 PE=1 SV=1 4.37 2563.1 - 333188 - - - -1.0938 - 2.573 0.651 - 424.7 1 2 0 -0.0017 13 0 0 0 5.41E+06 3.37E+06 - - - 6.2743 0.9989 221125_WJC_METTL3_EV_vs_WT_F05.13856.13856.2 8.30E-05 28-Jul R.C[160.03]VSVQTDPTDEIPTK.K sp|P18583|SON_HUMAN 1 1688.7927 80.25 65696 13856 2 1688.790961 845.4036 Protein SON OS=Homo sapiens OX=9606 GN=SON PE=1 SV=4 4.03 2563.2 - 331876 - - - -1.0398 - 1.553 0.319 - 108.3 1 2 0 -0.0018 15 0 0 0 1.04E+07 1.30E+05 - - - 2.4788 1 221125_WJC_METTL3_EV_vs_WT_F05.13858.13858.3 1.74E-07 15/40 R.LVNHFVEEFK[136.11]R[166.11].K "sp|P0DMV8|HS71A_HUMAN,sp|P0DMV9|HS71B_HUMAN,tr|V9GZ37|V9GZ37_HUMAN,tr|A0A0G2JIW1|A0A0G2JIW1_HUMAN" 4 1434.7739 0.14 65697 13858 3 1434.77342 479.2652 Heat shock 70 kDa protein 1A OS=Homo sapiens OX=9606 GN=HSPA1A PE=1 SV=1 6.76 2563.5 - 1.09E+08 - - - -0.3025 - 2.927 0.601 - 540.8 1 2 0 -0.0004 11 0 0 0 2.70E+08 1.99E+09 - - - 8.2914 0.9998 221125_WJC_METTL3_EV_vs_WT_F05.13862.13862.3 0.0138 Nov-32 R.EFADFEYRK.T "sp|Q8ND56|LS14A_HUMAN,tr|A0A140TA66|A0A140TA66_HUMAN" 2 1203.556 0.86 65700 13862 3 1203.555464 402.1926 Protein LSM14 homolog A OS=Homo sapiens OX=9606 GN=LSM14A PE=1 SV=3 4.68 2563.9 - 1.20E+06 - - - -0.4769 - 2.101 0.35 - 158.3 1 2 0 -0.0006 9 0 0 0 1.90E+07 2.19E+07 - - - 4.6795 0.9999 221125_WJC_METTL3_EV_vs_WT_F05.13863.13863.2 5.15E-06 15/24 R.NEQDAYAINSYTR.S "sp|P24752|THIL_HUMAN,tr|A0A5F9ZHJ7|A0A5F9ZHJ7_HUMAN,tr|A0A5F9ZHD4|A0A5F9ZHD4_HUMAN,tr|A0A5F9ZHJ0|A0A5F9ZHJ0_HUMAN,tr|A0A5F9ZHL1|A0A5F9ZHL1_HUMAN,tr|A0A5F9ZI66|A0A5F9ZI66_HUMAN" 6 1543.6903 1.24 65701 13863 2 1543.689755 772.8524 "Acetyl-CoA acetyltransferase, mitochondrial OS=Homo sapiens OX=9606 GN=ACAT1 PE=1 SV=1" 4.37 2564 - 942472 - - - -0.3531 - 3.094 0.377 - 1100 1 2 0 -0.0005 13 0 0 0 1.68E+08 1.36E+08 - - - 4.7242 0.9998 221125_WJC_METTL3_EV_vs_WT_F05.13864.13864.2 2.23E-05 20-Nov R.C[160.03]EDC[160.03]DQLFESK.A "sp|Q03112|MECOM_HUMAN,tr|E7ERX0|E7ERX0_HUMAN,tr|E7EUL6|E7EUL6_HUMAN,tr|A0A0C3SFZ7|A0A0C3SFZ7_HUMAN,tr|E7EPY2|E7EPY2_HUMAN,tr|E7EU48|E7EU48_HUMAN" 6 1429.549 1.64 65702 13864 2 1429.549368 715.7818 Histone-lysine N-methyltransferase MECOM OS=Homo sapiens OX=9606 GN=MECOM PE=1 SV=3 3.92 2564.1 - 768161 - - - 0.2707 - 2.163 0.38 - 596.1 1 2 0 0.0004 11 0 0 0 6.61E+06 4.03E+06 - - - 3.9346 0.9999 221125_WJC_METTL3_EV_vs_WT_F05.13865.13865.3 0.000124 Nov-48 K.VNKPMELYYAPTK.E sp|Q99496|RING2_HUMAN 1 1552.796 1.87 65703 13865 3 1552.794796 518.6059 E3 ubiquitin-protein ligase RING2 OS=Homo sapiens OX=9606 GN=RNF2 PE=1 SV=1 8.4 2564.3 - 729601 - - - -0.7438 - 1.98 0.447 - 132.7 1 2 0 -0.0012 13 0 0 0 1.48E+07 7.91E+06 - - - 5.3754 0.9998 221125_WJC_METTL3_EV_vs_WT_F05.13875.13875.3 0.000106 17/56 R.STSHK[136.11]PDEIYGMIER[166.11].L sp|Q86U44|MTA70_HUMAN 1 1779.8581 0.06 65711 13875 3 1779.857677 594.2933 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 5.42 2565.3 - 1.47E+06 - - - -0.2118 - 2.474 0.322 - 193.1 1 2 0 -0.0004 15 0 0 0 2.27E+06 4.05E+07 - - - 4.4935 0.9945 221125_WJC_METTL3_EV_vs_WT_F05.13881.13881.3 0.0136 Oct-64 R.VNSLAPGPISGTEGLR[166.11]R[166.11].L "sp|Q9NUI1|DECR2_HUMAN,tr|A0A0J9YWI0|A0A0J9YWI0_HUMAN,tr|Q4VXZ8|Q4VXZ8_HUMAN" 3 1742.9542 1.08 65717 13881 3 1742.953254 581.992 "Peroxisomal 2,4-dienoyl-CoA reductase [(3E)-enoyl-CoA-producing] OS=Homo sapiens OX=9606 GN=DECR2 PE=1 SV=1" 9.57 2566.1 - 244008 - - - -0.5554 - 2.052 0.163 - 98.1 1 2 0 -0.001 17 0 0 0 6.30E+06 5.81E+06 - - - 2.173 0.9984 221125_WJC_METTL3_EV_vs_WT_F05.13886.13886.3 0.0342 Nov-36 R.R[166.11]K[136.11]PFYPALIR[166.11].Y "sp|O00746|NDKM_HUMAN,tr|Q4TT34|Q4TT34_HUMAN,tr|H0Y6J0|H0Y6J0_HUMAN,tr|F2Z2X0|F2Z2X0_HUMAN,tr|A2IDC9|A2IDC9_HUMAN" 5 1287.781 1.87 65720 13886 3 1287.779703 430.2676 "Nucleoside diphosphate kinase, mitochondrial OS=Homo sapiens OX=9606 GN=NME4 PE=1 SV=1" 11 2566.6 - 2.70E+06 - - - -1.0087 - 1.737 0.256 - 173.4 1 2 0 -0.0013 10 0 0 0 8.90E+08 4.77E+08 - - - 3.0063 0.9997 221125_WJC_METTL3_EV_vs_WT_F05.13888.13888.2 0.000424 13/20 K.HLSVNDLPVGR[166.11].S sp|P30048|PRDX3_HUMAN 1 1215.6599 0.6 65722 13888 2 1215.660165 608.8372 "Thioredoxin-dependent peroxide reductase, mitochondrial OS=Homo sapiens OX=9606 GN=PRDX3 PE=1 SV=3" 6.74 2566.8 - 801004 - - - 0.1851 - 2.49 0.283 - 575.3 1 2 0 0.0002 11 0 0 0 1.04E+07 1.74E+07 - - - 3.5991 0.9993 221125_WJC_METTL3_EV_vs_WT_F05.13895.13895.2 0.000265 20-Sep R.AQHLADILSSK.G "sp|Q9UHI6|DDX20_HUMAN,tr|A0A7P0T8G7|A0A7P0T8G7_HUMAN,tr|A0A7P0TB94|A0A7P0TB94_HUMAN,tr|A0A7P0T9T8|A0A7P0T9T8_HUMAN" 4 1181.6404 1.55 65729 13895 2 1181.642134 591.8275 Probable ATP-dependent RNA helicase DDX20 OS=Homo sapiens OX=9606 GN=DDX20 PE=1 SV=2 6.79 2567.7 - 385604 - - - 1.4361 - 1.654 0.369 - 143.3 1 2 0 0.0017 11 0 0 0 4.71E+06 3.03E+06 - - - 3.1272 0.9946 221125_WJC_METTL3_EV_vs_WT_F05.13898.13898.3 0.00266 Nov-36 R.RKPFYPALIR.Y "sp|O00746|NDKM_HUMAN,tr|Q4TT34|Q4TT34_HUMAN,tr|H0Y6J0|H0Y6J0_HUMAN,tr|F2Z2X0|F2Z2X0_HUMAN,tr|A2IDC9|A2IDC9_HUMAN" 5 1259.7503 1.87 65731 13898 3 1259.749331 420.924 "Nucleoside diphosphate kinase, mitochondrial OS=Homo sapiens OX=9606 GN=NME4 PE=1 SV=1" 11 2568 - 4.64E+06 - - - -0.739 - 2.021 0.143 - 160.6 1 2 0 -0.0009 10 0 0 0 8.93E+08 4.79E+08 - - - 2.1889 0.9999 221125_WJC_METTL3_EV_vs_WT_F05.13900.13900.4 0.000263 15/84 R.STSHK[136.11]PDEIYGMIER[166.11].L sp|Q86U44|MTA70_HUMAN 1 1779.8581 0.001 65732 13900 4 1779.857163 445.9718 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 5.42 2568.2 - 1.64E+06 - - - -0.5006 - 2.342 0.419 - 143.4 1 2 0 -0.0009 15 0 0 0 0.00E+00 2.39E+07 - - - 3.1772 0.9999 221125_WJC_METTL3_EV_vs_WT_F05.13901.13901.3 6.10E-08 13/48 R.NEQDAYAINSYTR.S "sp|P24752|THIL_HUMAN,tr|A0A5F9ZHJ7|A0A5F9ZHJ7_HUMAN,tr|A0A5F9ZHD4|A0A5F9ZHD4_HUMAN,tr|A0A5F9ZHJ0|A0A5F9ZHJ0_HUMAN,tr|A0A5F9ZHL1|A0A5F9ZHL1_HUMAN,tr|A0A5F9ZI66|A0A5F9ZI66_HUMAN" 6 1543.6903 1.51 65733 13901 3 1543.695208 515.5707 "Acetyl-CoA acetyltransferase, mitochondrial OS=Homo sapiens OX=9606 GN=ACAT1 PE=1 SV=1" 4.37 2568.3 - 1.92E+06 - - - 3.1794 - 2.569 0.578 - 282 1 2 0 0.0049 13 0 0 0 2.62E+07 1.74E+07 - - - 7.5409 0.9965 221125_WJC_METTL3_EV_vs_WT_F05.13902.13902.3 0.058 Oct-40 K.HLSVNDLPVGR.S sp|P30048|PRDX3_HUMAN 1 1205.6517 0.44 65734 13902 3 1205.651332 402.8912 "Thioredoxin-dependent peroxide reductase, mitochondrial OS=Homo sapiens OX=9606 GN=PRDX3 PE=1 SV=3" 6.74 2568.3 - 1.79E+06 - - - -0.2803 - 1.707 0.215 - 128.2 1 2 0 -0.0003 11 0 0 0 1.87E+07 4.23E+07 - - - 2.456 0.9995 221125_WJC_METTL3_EV_vs_WT_F05.13907.13907.2 0.0329 22-Oct R.LQDLSSC[160.03]ITQGK[136.11].D "sp|P29590|PML_HUMAN,tr|H3BUJ5|H3BUJ5_HUMAN,tr|H3BT29|H3BT29_HUMAN,tr|H3BVD2|H3BVD2_HUMAN,tr|H3BT57|H3BT57_HUMAN" 5 1356.6799 1.55 65739 13907 2 1356.676811 679.3472 Protein PML OS=Homo sapiens OX=9606 GN=PML PE=1 SV=3 5.83 2568.9 - 533095 - - - -2.2518 - 2.164 0.418 - 421.1 1 2 0 -0.0031 12 0 0 0 8.26E+06 5.34E+06 - - - 4.1585 0.9999 221125_WJC_METTL3_EV_vs_WT_F05.13908.13908.3 6.22E-05 15/52 R.GGNNSFTHEALTLK.Y sp|P08240|SRPRA_HUMAN 1 1487.7369 1.81 65740 13908 3 1487.738614 496.9196 Signal recognition particle receptor subunit alpha OS=Homo sapiens OX=9606 GN=SRPRA PE=1 SV=2 6.75 2569 - 528147 - - - 1.1817 - 2.236 0.412 - 348.3 1 2 0 0.0018 14 0 0 0 8.31E+06 4.60E+06 - - - 5.2714 0.9996 221125_WJC_METTL3_EV_vs_WT_F05.13909.13909.3 0.00607 Nov-44 K.KGNFILSAGVDK.T "sp|Q9BZK7|TBL1R_HUMAN,tr|A0A1B0GVH3|A0A1B0GVH3_HUMAN,tr|A0A0D9SF63|A0A0D9SF63_HUMAN" 3 1247.6874 2.44 65741 13909 3 1247.687408 416.9031 F-box-like\WD repeat-containing protein TBL1XR1 OS=Homo sapiens OX=9606 GN=TBL1XR1 PE=1 SV=1 8.59 2569.1 - 524406 - - - 0.0168 - 2.179 0.302 - 246.5 1 2 0 0 12 0 0 0 6.97E+06 2.85E+06 - - - 4.0659 0.9999 221125_WJC_METTL3_EV_vs_WT_F05.13912.13912.2 1.29E-06 30-Oct R.EADGSETPEPFAAEAK[136.11].F sp|Q7KZF4|SND1_HUMAN 1 1655.7406 0.98 65744 13912 2 1655.742436 828.8776 Staphylococcal nuclease domain-containing protein 1 OS=Homo sapiens OX=9606 GN=SND1 PE=1 SV=1 3.91 2569.5 - 188636 - - - 1.1022 - 2.076 0.587 - 249.7 1 2 0 0.0018 16 0 0 0 6.61E+06 6.74E+06 - - - 5.1718 1 221125_WJC_METTL3_EV_vs_WT_F05.13917.13917.3 9.60E-07 13/48 R.NEQDAYAINSYTR[166.11].S "sp|P24752|THIL_HUMAN,tr|A0A5F9ZHJ7|A0A5F9ZHJ7_HUMAN,tr|A0A5F9ZHD4|A0A5F9ZHD4_HUMAN,tr|A0A5F9ZHJ0|A0A5F9ZHJ0_HUMAN,tr|A0A5F9ZHL1|A0A5F9ZHL1_HUMAN,tr|A0A5F9ZI66|A0A5F9ZI66_HUMAN" 6 1553.6986 1.49 65747 13917 3 1553.699244 518.9068 "Acetyl-CoA acetyltransferase, mitochondrial OS=Homo sapiens OX=9606 GN=ACAT1 PE=1 SV=1" 4.37 2570 - 2.01E+06 - - - 0.4338 - 1.991 0.674 - 213.9 1 2 0 0.0007 13 0 0 0 2.60E+07 1.74E+07 - - - 7.9213 1 221125_WJC_METTL3_EV_vs_WT_F05.13921.13921.2 2.63E-06 26-Dec K.NSSTIIQNPVETPK.K sp|P38432|COIL_HUMAN 1 1526.794 1.22 65751 13921 2 1526.795354 764.4043 Coilin OS=Homo sapiens OX=9606 GN=COIL PE=1 SV=1 6 2570.5 - 500731 - - - 0.8626 - 2.543 0.591 - 556.5 1 2 0 0.0013 14 0 0 0 6.68E+06 5.48E+06 - - - 5.7479 0.9998 221125_WJC_METTL3_EV_vs_WT_F05.13924.13924.2 1.51E-05 26-Dec K.LSTEQINSQIAQTK.S sp|Q63HK5|TSH3_HUMAN 1 1559.8155 6.26 65754 13924 2 1559.816061 780.915 Teashirt homolog 3 OS=Homo sapiens OX=9606 GN=TSHZ3 PE=1 SV=2 6 2570.8 - 550026 - - - 0.359 - 2.283 0.445 - 536.6 1 2 0 0.0006 14 0 0 0 3.36E+06 5.38E+05 - - - 4.3991 0.9996 221125_WJC_METTL3_EV_vs_WT_F05.13925.13925.2 7.68E-06 14/22 K.QQIQSIQQSIER[166.11].L "sp|P55769|NH2L1_HUMAN,tr|B1AHD1|B1AHD1_HUMAN,tr|A0A3B3IUA2|A0A3B3IUA2_HUMAN,tr|A0A3B3IRU2|A0A3B3IRU2_HUMAN" 4 1466.7717 1.63 65755 13925 2 1466.775178 734.3931 NHP2-like protein 1 OS=Homo sapiens OX=9606 GN=SNU13 PE=1 SV=3 6 2571 - 271244 - - - 2.3882 - 2.647 0.424 - 841.6 1 2 0 0.0035 12 0 0 0 1.37E+08 8.39E+07 - - - 4.7328 0.9997 221125_WJC_METTL3_EV_vs_WT_F05.13926.13926.3 1.22E-06 Dec-56 K.ITC[160.03]DK[136.11]ESEGTLLLSR[166.11].L "sp|Q9Y2W6|TDRKH_HUMAN,tr|F6TB26|F6TB26_HUMAN,tr|Q5SZR4|Q5SZR4_HUMAN" 3 1738.889 1.4 65756 13926 3 1738.884711 580.6369 Tudor and KH domain-containing protein OS=Homo sapiens OX=9606 GN=TDRKH PE=1 SV=2 4.68 2571.1 - 252761 - - - -2.478 - 2.642 0.52 - 143.7 1 2 1 -0.0043 15 0 0 0 8.46E+06 6.03E+06 - - - 6.8714 0.9999 221125_WJC_METTL3_EV_vs_WT_F05.13927.13927.4 0.00069 Nov-78 K.VTLSEGPHHVALFK[136.11].D "sp|O60313|OPA1_HUMAN,tr|A0A2R8YD53|A0A2R8YD53_HUMAN,tr|C9JMB8|C9JMB8_HUMAN,tr|A0A2R8YE54|A0A2R8YE54_HUMAN,tr|A0A2R8YDM2|A0A2R8YDM2_HUMAN,tr|E5KLJ9|E5KLJ9_HUMAN,tr|A0A2R8Y4Q3|A0A2R8Y4Q3_HUMAN,tr|A0A2R8Y3X5|A0A2R8Y3X5_HUMAN,tr|A0A2R8YGE5|A0A2R8YGE5_HUMAN,tr|A0A2R8YFD1|A0A2R8YFD1_HUMAN,tr|A0A2R8Y4G4|A0A2R8Y4G4_HUMAN,tr|A0A2R8YE78|A0A2R8YE78_HUMAN" 12 1541.8446 1.13 65757 13927 4 1541.846362 386.4684 "Dynamin-like 120 kDa protein, mitochondrial OS=Homo sapiens OX=9606 GN=OPA1 PE=1 SV=3" 6.89 2571.2 - 235331 - - - 1.1668 - 1.821 0.428 - 84 1 2 0 0.0018 14 0 0 0 3.35E+06 2.98E+06 - - - 3.169 0.9998 221125_WJC_METTL3_EV_vs_WT_F05.13928.13928.2 0.000886 20-Aug K.AQIWDTAGQER.Y "sp|Q15907|RB11B_HUMAN,sp|P62491|RB11A_HUMAN,tr|H3BMH2|H3BMH2_HUMAN,tr|H3BSC1|H3BSC1_HUMAN" 4 1273.6051 1.21 65758 13928 2 1273.605395 637.8098 Ras-related protein Rab-11B OS=Homo sapiens OX=9606 GN=RAB11B PE=1 SV=4 4.37 2571.4 - 203123 - - - 0.2206 - 1.81 0.46 - 236.1 1 2 0 0.0003 11 0 0 0 2.33E+06 1.92E+06 - - - 4.0436 0.9559 221125_WJC_METTL3_EV_vs_WT_F05.13930.13930.3 0.365 Nov-44 K.ADDGRPFPQVIK.S "sp|P04075|ALDOA_HUMAN,tr|H3BR04|H3BR04_HUMAN,tr|H3BMQ8|H3BMQ8_HUMAN,tr|H3BU78|H3BU78_HUMAN,tr|H3BQN4|H3BQN4_HUMAN,tr|H3BUH7|H3BUH7_HUMAN,tr|J3KPS3|J3KPS3_HUMAN,tr|H3BPS8|H3BPS8_HUMAN" 8 1341.7041 1.47 65759 13930 3 1341.704147 448.242 Fructose-bisphosphate aldolase A OS=Homo sapiens OX=9606 GN=ALDOA PE=1 SV=2 6 2571.6 - 2.46E+06 - - - 0.035 - 2.065 0.034 - 160.5 1 2 0 0 12 0 0 0 7.53E+07 5.13E+07 - - - 0.929 0.9999 221125_WJC_METTL3_EV_vs_WT_F05.13934.13934.2 9.42E-05 13/22 K.QQIQSIQQSIER.L "sp|P55769|NH2L1_HUMAN,tr|B1AHD1|B1AHD1_HUMAN,tr|A0A3B3IUA2|A0A3B3IUA2_HUMAN,tr|A0A3B3IRU2|A0A3B3IRU2_HUMAN" 4 1456.7634 1.63 65762 13934 2 1456.765252 729.389 NHP2-like protein 1 OS=Homo sapiens OX=9606 GN=SNU13 PE=1 SV=3 6 2572 - 1.42E+06 - - - 1.2672 - 2.807 0.472 - 867.5 1 2 0 0.0018 12 0 0 0 1.37E+08 8.39E+07 - - - 5.2423 0.9735 221125_WJC_METTL3_EV_vs_WT_F05.13936.13936.3 0.00126 Dec-40 Q.TYQPYNK[136.11]DWIK[136.11].E sp|P84090|ERH_HUMAN 1 1470.7478 4.89 65764 13936 3 1470.748546 491.2565 Enhancer of rudimentary homolog OS=Homo sapiens OX=9606 GN=ERH PE=1 SV=1 8.1 2572.1 - 973987 - - - 0.497 - 2.21 0.447 - 184.5 1 1 1 0.0007 11 0 0 0 4.09E+07 8.37E+06 - - - 5.7762 0.9996 221125_WJC_METTL3_EV_vs_WT_F05.13937.13937.3 0.236 Dec-56 K.LKPNLGNGADLPNYR.W "sp|Q9Y266|NUDC_HUMAN,tr|A0A0A0MSS4|A0A0A0MSS4_HUMAN,tr|A0A0A0MSU9|A0A0A0MSU9_HUMAN" 3 1640.8635 1.87 65765 13937 3 1640.866917 547.9618 Nuclear migration protein nudC OS=Homo sapiens OX=9606 GN=NUDC PE=1 SV=1 8.59 2572.2 - 805931 - - - 2.1105 - 2.396 0.343 - 132.3 1 2 0 0.0035 15 0 0 0 1.66E+08 8.89E+07 - - - 4.6432 0.9996 221125_WJC_METTL3_EV_vs_WT_F05.13938.13938.3 3.20E-08 18/60 K.WENPGLGAESHTDSLR.N "sp|Q9UHB6|LIMA1_HUMAN,tr|F8VVQ7|F8VVQ7_HUMAN,tr|F8VRN8|F8VRN8_HUMAN,tr|F8VTU2|F8VTU2_HUMAN" 4 1767.8176 0.62 65766 13938 3 1767.827572 590.2798 LIM domain and actin-binding protein 1 OS=Homo sapiens OX=9606 GN=LIMA1 PE=1 SV=1 4.65 2572.3 - 603754 - - - 5.6261 - 2.925 0.567 - 411.2 1 2 0 0.0099 16 0 0 0 7.13E+06 1.14E+07 - - - 7.6127 0.9998 221125_WJC_METTL3_EV_vs_WT_F05.13939.13939.3 0.00992 Oct-56 K.LK[136.11]PNLGNGADLPNYR[166.11].W "sp|Q9Y266|NUDC_HUMAN,tr|A0A0A0MSS4|A0A0A0MSS4_HUMAN,tr|A0A0A0MSU9|A0A0A0MSU9_HUMAN" 3 1658.8859 2.12 65767 13939 3 1658.887924 553.9693 Nuclear migration protein nudC OS=Homo sapiens OX=9606 GN=NUDC PE=1 SV=1 8.59 2572.4 - 556719 - - - 1.2056 - 2.058 0.372 - 101.8 1 2 0 0.002 15 0 0 0 1.93E+08 9.09E+07 - - - 4.5701 0.9278 221125_WJC_METTL3_EV_vs_WT_F05.13940.13940.3 0.000363 Dec-52 K.FKDPNC[160.03]VGTVLASR.P "sp|Q96EP5|DAZP1_HUMAN,tr|K7EK33|K7EK33_HUMAN,tr|K7EQ55|K7EQ55_HUMAN,tr|K7EQ02|K7EQ02_HUMAN" 4 1562.7875 1.28 65768 13940 3 1562.790139 521.9364 DAZ-associated protein 1 OS=Homo sapiens OX=9606 GN=DAZAP1 PE=1 SV=1 8.22 2572.6 - 420533 - - - 1.681 - 2.111 0.418 - 139.2 1 1 1 0.0026 14 0 0 0 6.64E+06 5.20E+06 - - - 5.1852 0.9999 221125_WJC_METTL3_EV_vs_WT_F05.13945.13945.3 6.55E-05 18/60 K.IR[166.11]LESEEEGVPSTAIR[166.11].E "sp|P06493|CDK1_HUMAN,tr|E5RIU6|E5RIU6_HUMAN,tr|A0A024QZP7|A0A024QZP7_HUMAN,tr|A0A087WZZ9|A0A087WZZ9_HUMAN" 4 1804.9434 5.59 65771 13945 3 1804.944855 602.6551 Cyclin-dependent kinase 1 OS=Homo sapiens OX=9606 GN=CDK1 PE=1 SV=3 4.49 2573.1 - 885555 - - - 0.8161 - 3.11 0.538 - 300.5 1 2 1 0.0015 16 0 0 0 5.39E+07 9.65E+06 - - - 7.449 0.9893 221125_WJC_METTL3_EV_vs_WT_F05.13946.13946.3 1.19E-06 19/56 Y.LLSSAYVDSHKWEAR.E "sp|Q92552|RT27_HUMAN,tr|E5RJ73|E5RJ73_HUMAN" 2 1760.8846 2.28 65772 13946 3 1760.887366 587.9688 "28S ribosomal protein S27, mitochondrial OS=Homo sapiens OX=9606 GN=MRPS27 PE=1 SV=3" 6.75 2573.3 - 529082 - - - 1.5805 - 2.969 0.551 - 503.4 1 1 1 0.0028 15 0 0 0 8.49E+06 3.72E+06 - - - 7.5219 0.9993 221125_WJC_METTL3_EV_vs_WT_F05.13947.13947.2 2.41E-05 15/28 R.VSLAGAC[160.03]GVGGYGSR.S "sp|P13647|K2C5_HUMAN,tr|F8VV57|F8VV57_HUMAN" 2 1409.6721 999 65773 13947 2 1409.667502 705.8434 "Keratin, type II cytoskeletal 5 OS=Homo sapiens OX=9606 GN=KRT5 PE=1 SV=3" 8.19 2573.4 - 427920 - - - -3.2958 - 2.564 0.478 - 759.7 1 2 0 -0.0046 15 0 0 0 7.12E+06 0.00E+00 - - - 4.8849 0.997 221125_WJC_METTL3_EV_vs_WT_F05.13948.13948.4 0.0161 Nov-78 K.VTLSEGPHHVALFK.D "sp|O60313|OPA1_HUMAN,tr|A0A2R8YD53|A0A2R8YD53_HUMAN,tr|C9JMB8|C9JMB8_HUMAN,tr|A0A2R8YE54|A0A2R8YE54_HUMAN,tr|A0A2R8YDM2|A0A2R8YDM2_HUMAN,tr|E5KLJ9|E5KLJ9_HUMAN,tr|A0A2R8Y4Q3|A0A2R8Y4Q3_HUMAN,tr|A0A2R8Y3X5|A0A2R8Y3X5_HUMAN,tr|A0A2R8YGE5|A0A2R8YGE5_HUMAN,tr|A0A2R8YFD1|A0A2R8YFD1_HUMAN,tr|A0A2R8Y4G4|A0A2R8Y4G4_HUMAN,tr|A0A2R8YE78|A0A2R8YE78_HUMAN" 12 1533.8304 1.13 65774 13948 4 1533.829938 384.4649 "Dynamin-like 120 kDa protein, mitochondrial OS=Homo sapiens OX=9606 GN=OPA1 PE=1 SV=3" 6.89 2573.5 - 427369 - - - -0.2771 - 1.454 0.259 - 72.4 1 2 0 -0.0004 14 0 0 0 3.35E+06 2.98E+06 - - - 1.6164 0.9997 221125_WJC_METTL3_EV_vs_WT_F05.13949.13949.2 0.000431 24-Oct K.SSDQPLTVPVSPK[136.11].F sp|Q9ULW0|TPX2_HUMAN 1 1361.7282 1.27 65775 13949 2 1361.730685 681.8714 Targeting protein for Xklp2 OS=Homo sapiens OX=9606 GN=TPX2 PE=1 SV=2 5.55 2573.6 - 326852 - - - 1.8278 - 2.4 0.443 - 351 1 2 0 0.0025 13 0 0 0 7.35E+06 5.81E+06 - - - 4.5591 0.9975 221125_WJC_METTL3_EV_vs_WT_F05.13951.13951.3 0.0052 Dec-56 K.DK[136.11]YVGVSSDSVGGFR[166.11].Y sp|Q14677|EPN4_HUMAN 1 1589.7805 1.86 65777 13951 3 1589.782092 530.9341 Clathrin interactor 1 OS=Homo sapiens OX=9606 GN=CLINT1 PE=1 SV=1 5.96 2573.9 - 318037 - - - 1.0291 - 1.99 0.315 - 151.9 1 2 1 0.0016 15 0 0 0 1.33E+07 7.15E+06 - - - 3.8471 0.9999 221125_WJC_METTL3_EV_vs_WT_F05.13952.13952.3 1.51E-05 Nov-64 R.AVADQVYGDQDMHEVVR[166.11].K "sp|Q96G74|OTUD5_HUMAN,tr|A0A087WXV6|A0A087WXV6_HUMAN,tr|H7BZQ3|H7BZQ3_HUMAN" 3 1940.8926 0.2 65778 13952 3 1940.896823 647.9715 OTU domain-containing protein 5 OS=Homo sapiens OX=9606 GN=OTUD5 PE=1 SV=1 4.22 2574 - 287837 - - - 2.1784 - 2.369 0.471 - 119 1 2 0 0.0042 17 0 0 0 4.54E+05 2.31E+06 - - - 5.9689 1 221125_WJC_METTL3_EV_vs_WT_F05.13953.13953.2 8.62E-08 14/26 R.YGDSEFTVQSTTGH.C sp|P52597|HNRPF_HUMAN 1 1527.6478 - 65779 13953 2 1527.653392 764.8312 Heterogeneous nuclear ribonucleoprotein F OS=Homo sapiens OX=9606 GN=HNRNPF PE=1 SV=3 4.35 2574.2 - 260417 - - - 3.6821 - 2.828 0.601 - 586.3 1 1 0 0.0056 14 0 0 0 - - - - - 6.087 0.9999 221125_WJC_METTL3_EV_vs_WT_F05.13956.13956.2 0.000229 Jul-32 R.FNDPSGC[160.03]APSPGAYDVK.T sp|O75330|HMMR_HUMAN 1 1780.7727 4.05 65782 13956 2 1780.772739 891.3936 Hyaluronan mediated motility receptor OS=Homo sapiens OX=9606 GN=HMMR PE=1 SV=2 4.21 2574.6 - 132892 - - - 0.05 - 1.667 0.595 - 98.7 1 2 0 0.0001 17 0 0 0 1.28E+06 3.16E+05 - - - 4.692 1 221125_WJC_METTL3_EV_vs_WT_F05.13958.13958.2 4.66E-11 16/30 R.EPSVPASC[160.03]AVSATYER.S "sp|Q92615|LAR4B_HUMAN,tr|H0Y641|H0Y641_HUMAN,tr|H0Y4V9|H0Y4V9_HUMAN" 3 1722.7883 1.31 65783 13958 2 1722.788881 862.4014 La-related protein 4B OS=Homo sapiens OX=9606 GN=LARP4B PE=1 SV=3 4.53 2574.8 - 620452 - - - 0.3372 - 2.831 0.689 - 498.9 1 2 0 0.0006 16 0 0 0 2.59E+08 1.98E+08 - - - 6.6882 0.9999 221125_WJC_METTL3_EV_vs_WT_F05.13959.13959.3 0.00861 14/44 R.KAVDEAADALLK.A "sp|Q16891|MIC60_HUMAN,tr|B9A067|B9A067_HUMAN,tr|C9J406|C9J406_HUMAN,tr|H7C463|H7C463_HUMAN" 4 1242.682 1.84 65784 13959 3 1242.681926 415.2346 MICOS complex subunit MIC60 OS=Homo sapiens OX=9606 GN=IMMT PE=1 SV=1 4.56 2574.9 - 902621 - - - -0.033 - 2.566 0.342 - 265.8 1 2 0 0 12 0 0 0 7.31E+06 3.98E+06 - - - 4.965 0.9971 221125_WJC_METTL3_EV_vs_WT_F05.13960.13960.3 0.00209 13/44 K.QQIQSIQQSIER.L "sp|P55769|NH2L1_HUMAN,tr|B1AHD1|B1AHD1_HUMAN,tr|A0A3B3IUA2|A0A3B3IUA2_HUMAN,tr|A0A3B3IRU2|A0A3B3IRU2_HUMAN" 4 1456.7634 1.91 65785 13960 3 1456.769447 486.5951 NHP2-like protein 1 OS=Homo sapiens OX=9606 GN=SNU13 PE=1 SV=3 6 2574.9 - 2.03E+06 - - - 4.1469 - 1.919 0.343 - 330.9 1 2 0 0.006 12 0 0 0 3.45E+07 1.81E+07 - - - 4.1691 0.9999 221125_WJC_METTL3_EV_vs_WT_F05.13961.13961.3 0.00545 13/44 K.LQNAFWEHGASR.A sp|Q8WUF5|IASPP_HUMAN 1 1414.6742 1.78 65786 13961 3 1414.675602 472.5653 RelA-associated inhibitor OS=Homo sapiens OX=9606 GN=PPP1R13L PE=1 SV=4 6.75 2575 - 1.35E+06 - - - 0.9939 - 2.314 0.38 - 190.8 1 2 0 0.0014 12 0 0 0 1.18E+07 6.63E+06 - - - 5.1018 0.9546 221125_WJC_METTL3_EV_vs_WT_F05.13962.13962.4 1.41E-07 17/84 Y.LLSSAYVDSHK[136.11]WEAR[166.11].E "sp|Q92552|RT27_HUMAN,tr|E5RJ73|E5RJ73_HUMAN" 2 1778.9071 1.13 65787 13962 4 1778.910489 445.734 "28S ribosomal protein S27, mitochondrial OS=Homo sapiens OX=9606 GN=MRPS27 PE=1 SV=3" 6.75 2575.1 - 1.28E+06 - - - 1.9315 - 2.976 0.441 - 245.9 1 1 1 0.0034 15 0 0 0 1.14E+07 1.01E+07 - - - 3.4537 0.9997 221125_WJC_METTL3_EV_vs_WT_F05.13963.13963.3 0.00857 Oct-40 R.ERPAAISIEIK.S sp|Q15208|STK38_HUMAN 1 1225.703 3.85 65788 13963 3 1225.703401 409.575 Serine\threonine-protein kinase 38 OS=Homo sapiens OX=9606 GN=STK38 PE=1 SV=1 6.24 2575.2 - 1.18E+06 - - - 0.297 - 1.83 0.356 - 128.4 1 2 0 0.0004 11 0 0 0 3.55E+07 9.22E+06 - - - 4.2257 0.9998 221125_WJC_METTL3_EV_vs_WT_F05.13965.13965.2 0.00301 15/30 R.EADGSETPEPFAAEAK.F sp|Q7KZF4|SND1_HUMAN 1 1647.7264 0.98 65790 13965 2 1647.72957 824.8705 Staphylococcal nuclease domain-containing protein 1 OS=Homo sapiens OX=9606 GN=SND1 PE=1 SV=1 3.91 2575.4 - 464092 - - - 1.9172 - 2.588 0.544 - 287.4 1 2 0 0.0032 16 0 0 0 6.61E+06 6.74E+06 - - - 5.3958 0.9994 221125_WJC_METTL3_EV_vs_WT_F05.13968.13968.2 1.29E-08 24-Nov K.TDPTTLTDEEINR.F "sp|P11586|C1TC_HUMAN,tr|F5H2F4|F5H2F4_HUMAN,tr|V9GZ78|V9GZ78_HUMAN,tr|V9GYY3|V9GYY3_HUMAN,tr|A0A494C1T2|A0A494C1T2_HUMAN" 5 1503.7053 1.47 65793 13968 2 1503.710577 752.8599 "C-1-tetrahydrofolate synthase, cytoplasmic OS=Homo sapiens OX=9606 GN=MTHFD1 PE=1 SV=4" 3.92 2575.8 - 105963 - - - 3.5213 - 2.137 0.632 - 357.9 1 2 0 0.0053 13 0 0 0 5.12E+07 3.49E+07 - - - 5.6563 0.9978 221125_WJC_METTL3_EV_vs_WT_F05.13972.13972.3 0.000965 13/44 K.QQIQSIQQSIER[166.11].L "sp|P55769|NH2L1_HUMAN,tr|B1AHD1|B1AHD1_HUMAN,tr|A0A3B3IUA2|A0A3B3IUA2_HUMAN,tr|A0A3B3IRU2|A0A3B3IRU2_HUMAN" 4 1466.7717 1.92 65795 13972 3 1466.777366 489.9312 NHP2-like protein 1 OS=Homo sapiens OX=9606 GN=SNU13 PE=1 SV=3 6 2576.3 - 2.60E+06 - - - 3.8799 - 2.19 0.314 - 374.5 1 2 0 0.0057 12 0 0 0 3.45E+07 1.79E+07 - - - 4.2121 0.9999 221125_WJC_METTL3_EV_vs_WT_F05.13974.13974.3 1.48E-08 13/56 K.DKYVGVSSDSVGGFR.Y sp|Q14677|EPN4_HUMAN 1 1571.758 1.52 65797 13974 3 1571.759881 524.9266 Clathrin interactor 1 OS=Homo sapiens OX=9606 GN=CLINT1 PE=1 SV=1 5.96 2576.4 - 1.42E+06 - - - 1.2057 - 2.609 0.565 - 205.4 1 2 1 0.0019 15 0 0 0 1.09E+07 7.15E+06 - - - 7.341 1 221125_WJC_METTL3_EV_vs_WT_F05.13976.13976.3 4.26E-07 19/52 K.QVLALQSQLADTK[136.11]K[136.11].K sp|P35580|MYH10_HUMAN 1 1557.9061 0.9 65799 13976 3 1557.906963 520.3093 Myosin-10 OS=Homo sapiens OX=9606 GN=MYH10 PE=1 SV=3 8.59 2576.7 - 960173 - - - 0.5495 - 2.82 0.496 - 458.6 1 2 0 0.0009 14 0 0 0 6.99E+06 7.73E+06 - - - 6.8248 0.9997 221125_WJC_METTL3_EV_vs_WT_F05.13981.13981.3 0.00253 Nov-44 R.K[136.11]AVDEAADALLK[136.11].A "sp|Q16891|MIC60_HUMAN,tr|B9A067|B9A067_HUMAN,tr|C9J406|C9J406_HUMAN,tr|H7C463|H7C463_HUMAN" 4 1258.7104 1.96 65804 13981 3 1258.711154 420.5774 MICOS complex subunit MIC60 OS=Homo sapiens OX=9606 GN=IMMT PE=1 SV=1 4.56 2577.2 - 524967 - - - 0.6252 - 2.201 0.303 - 214.7 1 2 0 0.0008 12 0 0 0 7.79E+06 3.98E+06 - - - 4.1047 0.9998 221125_WJC_METTL3_EV_vs_WT_F05.13983.13983.4 0.000304 14/78 R.LLSMAKPVYHAITK.H sp|O75643|U520_HUMAN 1 1570.8905 1.79 65806 13983 4 1570.892231 393.7299 U5 small nuclear ribonucleoprotein 200 kDa helicase OS=Homo sapiens OX=9606 GN=SNRNP200 PE=1 SV=2 9.7 2577.5 - 424136 - - - 1.0892 - 2.501 0.374 - 82.8 1 2 0 0.0017 14 0 0 0 4.35E+06 2.44E+06 - - - 2.8144 0.9999 221125_WJC_METTL3_EV_vs_WT_F05.13991.13991.3 3.85E-06 14/40 R.ER[166.11]PAAISIEIK[136.11].S sp|Q15208|STK38_HUMAN 1 1243.7255 3.85 65813 13991 3 1243.726076 415.5824 Serine\threonine-protein kinase 38 OS=Homo sapiens OX=9606 GN=STK38 PE=1 SV=1 6.24 2578.3 - 1.52E+06 - - - 0.4575 - 2.282 0.4 - 234.2 1 2 0 0.0006 11 0 0 0 3.55E+07 9.22E+06 - - - 5.3433 0.9999 221125_WJC_METTL3_EV_vs_WT_F05.13992.13992.3 0.000442 14/52 K.QVLALQSQLADTKK.K sp|P35580|MYH10_HUMAN 1 1541.8777 0.89 65814 13992 3 1541.880045 514.9665 Myosin-10 OS=Homo sapiens OX=9606 GN=MYH10 PE=1 SV=3 8.59 2578.4 - 1.27E+06 - - - 1.5163 - 2.639 0.406 - 240.2 1 2 0 0.0023 14 0 0 0 6.90E+06 7.73E+06 - - - 5.6447 1 221125_WJC_METTL3_EV_vs_WT_F05.13993.13993.3 3.53E-06 14/40 R.DAEDALHNLDR.K "sp|O75494|SRS10_HUMAN,tr|Q5JRI1|Q5JRI1_HUMAN" 2 1267.5793 1.92 65815 13993 3 1267.579864 423.5337 Serine\arginine-rich splicing factor 10 OS=Homo sapiens OX=9606 GN=SRSF10 PE=1 SV=1 4.22 2578.5 - 1.13E+06 - - - 0.4505 - 2.816 0.586 - 347 1 2 0 0.0006 11 0 0 0 2.20E+07 1.14E+07 - - - 8.0143 0.9998 221125_WJC_METTL3_EV_vs_WT_F05.13995.13995.2 0.000511 20-Sep K.SQQESWDLEEK.L "sp|Q9H3R5|CENPH_HUMAN,tr|B3KVZ3|B3KVZ3_HUMAN,tr|H0Y9E6|H0Y9E6_HUMAN" 3 1377.6048 4.02 65817 13995 2 1377.605223 689.8097 Centromere protein H OS=Homo sapiens OX=9606 GN=CENPH PE=1 SV=1 4 2578.8 - 944148 - - - 0.2787 - 2.193 0.435 - 283.1 1 2 0 0.0004 11 0 0 0 9.06E+06 2.26E+06 - - - 4.3781 0.9996 221125_WJC_METTL3_EV_vs_WT_F05.13996.13996.2 1.68E-06 13/22 K.TQLLQDVQDENK.L "sp|Q86UP2|KTN1_HUMAN,tr|G3V4Y7|G3V4Y7_HUMAN,tr|H0YJV5|H0YJV5_HUMAN" 3 1429.7049 2.33 65818 13996 2 1429.70149 715.8597 Kinectin OS=Homo sapiens OX=9606 GN=KTN1 PE=1 SV=1 4.03 2578.9 - 802210 - - - -2.3767 - 2.555 0.415 - 539.1 1 2 0 -0.0034 12 0 0 0 1.04E+07 4.46E+06 - - - 4.5733 0.9989 221125_WJC_METTL3_EV_vs_WT_F05.13997.13997.3 0.000379 Nov-48 K.VVSK[136.11]EESIVSSLR[166.11].L "sp|Q9NP61|ARFG3_HUMAN,tr|H0Y6A0|H0Y6A0_HUMAN" 2 1449.8158 0.87 65819 13997 3 1449.816749 484.2792 ADP-ribosylation factor GTPase-activating protein 3 OS=Homo sapiens OX=9606 GN=ARFGAP3 PE=1 SV=1 6.11 2579 - 773749 - - - 0.6691 - 2.275 0.33 - 139.9 1 2 1 0.001 13 0 0 0 8.24E+06 9.47E+06 - - - 4.4475 1 221125_WJC_METTL3_EV_vs_WT_F05.13998.13998.3 4.67E-05 13/40 R.DAEDALHNLDR[166.11].K "sp|O75494|SRS10_HUMAN,tr|Q5JRI1|Q5JRI1_HUMAN" 2 1277.5876 1.93 65820 13998 3 1277.588918 426.8698 Serine\arginine-rich splicing factor 10 OS=Homo sapiens OX=9606 GN=SRSF10 PE=1 SV=1 4.22 2579.1 - 580688 - - - 1.0606 - 2.379 0.531 - 243 1 2 0 0.0014 11 0 0 0 2.20E+07 1.14E+07 - - - 6.9218 0.9742 221125_WJC_METTL3_EV_vs_WT_F05.14006.14006.4 0.000155 16/84 Y.LLSSAYVDSHKWEAR.E "sp|Q92552|RT27_HUMAN,tr|E5RJ73|E5RJ73_HUMAN" 2 1760.8846 1.13 65827 14006 4 1760.885899 441.2284 "28S ribosomal protein S27, mitochondrial OS=Homo sapiens OX=9606 GN=MRPS27 PE=1 SV=3" 6.75 2580 - 621872 - - - 0.7474 - 2.8 0.457 - 196.5 1 1 1 0.0013 15 0 0 0 1.14E+07 1.01E+07 - - - 3.5718 1 221125_WJC_METTL3_EV_vs_WT_F05.14007.14007.2 1.36E-08 14/26 K.SGSGTMNLGGSLTR[166.11].Q "sp|P47756|CAPZB_HUMAN,tr|B1AK87|B1AK87_HUMAN,tr|B1AK88|B1AK88_HUMAN,tr|B1AK85|B1AK85_HUMAN" 4 1346.6488 0.4 65828 14007 2 1346.64835 674.3317 F-actin-capping protein subunit beta OS=Homo sapiens OX=9606 GN=CAPZB PE=1 SV=4 9.47 2580.1 - 1.59E+06 - - - -0.3215 - 2.721 0.606 - 470 1 2 0 -0.0004 14 0 0 0 4.88E+06 1.23E+07 - - - 6.0287 1 221125_WJC_METTL3_EV_vs_WT_F05.14008.14008.3 1.07E-07 21/68 K.LPTEVNHVPSGPSIPADR.T sp|Q96T58|MINT_HUMAN 1 1884.9694 2.33 65829 14008 3 1884.970708 629.3304 Msx2-interacting protein OS=Homo sapiens OX=9606 GN=SPEN PE=1 SV=1 5.32 2580.2 - 1.40E+06 - - - 0.7066 - 3.844 0.592 - 421.7 1 2 0 0.0013 18 0 0 0 3.05E+07 1.31E+07 - - - 8.4928 0.9999 221125_WJC_METTL3_EV_vs_WT_F05.14010.14010.2 8.92E-05 13/22 K.NAGVEGSLIVEK[136.11].L "sp|P10809|CH60_HUMAN,tr|A0A7I2V2X6|A0A7I2V2X6_HUMAN,tr|A0A7I2YQK6|A0A7I2YQK6_HUMAN,tr|A0A7I2V599|A0A7I2V599_HUMAN" 4 1222.6649 1.42 65831 14010 2 1222.665751 612.3397 "60 kDa heat shock protein, mitochondrial OS=Homo sapiens OX=9606 GN=HSPD1 PE=1 SV=2" 4.53 2580.4 - 951940 - - - 0.723 - 2.521 0.51 - 556.1 1 2 0 0.0009 12 0 0 0 2.38E+07 1.68E+07 - - - 5.2405 0.9998 221125_WJC_METTL3_EV_vs_WT_F05.14011.14011.2 3.17E-06 14/22 K.NAGVEGSLIVEK.L "sp|P10809|CH60_HUMAN,tr|A0A7I2V2X6|A0A7I2V2X6_HUMAN,tr|A0A7I2YQK6|A0A7I2YQK6_HUMAN,tr|A0A7I2V599|A0A7I2V599_HUMAN" 4 1214.6507 1.35 65832 14011 2 1214.652993 608.3326 "60 kDa heat shock protein, mitochondrial OS=Homo sapiens OX=9606 GN=HSPD1 PE=1 SV=2" 4.53 2580.6 - 840793 - - - 1.915 - 2.67 0.494 - 689 1 2 0 0.0023 12 0 0 0 2.27E+07 1.68E+07 - - - 5.273 0.9951 221125_WJC_METTL3_EV_vs_WT_F05.14016.14016.2 6.67E-09 14/28 K.LKPNLGNGADLPNYR.W "sp|Q9Y266|NUDC_HUMAN,tr|A0A0A0MSS4|A0A0A0MSS4_HUMAN,tr|A0A0A0MSU9|A0A0A0MSU9_HUMAN" 3 1640.8635 1.16 65837 14016 2 1640.874347 821.439 Nuclear migration protein nudC OS=Homo sapiens OX=9606 GN=NUDC PE=1 SV=1 8.59 2581.1 - 374794 - - - 6.6386 - 2.425 0.595 - 608.2 1 2 0 0.0109 15 0 0 0 2.14E+06 1.84E+06 - - - 5.6101 0.9999 221125_WJC_METTL3_EV_vs_WT_F05.14017.14017.2 8.11E-05 20-Oct K.SQQESWDLEEK[136.11].L "sp|Q9H3R5|CENPH_HUMAN,tr|B3KVZ3|B3KVZ3_HUMAN,tr|H0Y9E6|H0Y9E6_HUMAN" 3 1385.619 4.02 65838 14017 2 1385.62007 693.8168 Centromere protein H OS=Homo sapiens OX=9606 GN=CENPH PE=1 SV=1 4 2581.2 - 326252 - - - 0.7441 - 2.237 0.532 - 391.1 1 2 0 0.001 11 0 0 0 9.06E+06 2.26E+06 - - - 5.1481 0.9998 221125_WJC_METTL3_EV_vs_WT_F05.14018.14018.2 0.0223 14/26 K.SQLVEIEPATQNPK.T "sp|Q9BYP7|WNK3_HUMAN,tr|A0A087WYK2|A0A087WYK2_HUMAN" 2 1552.8097 1.05 65839 14018 2 1552.811431 777.4121 Serine\threonine-protein kinase WNK3 OS=Homo sapiens OX=9606 GN=WNK3 PE=1 SV=3 4.53 2581.4 - 317650 - - - 1.1231 - 2.617 0.488 - 560.6 1 2 0 0.0017 14 0 0 0 3.57E+06 3.42E+06 - - - 5.059 0.9999 221125_WJC_METTL3_EV_vs_WT_F05.14020.14020.2 7.19E-09 30-Sep R.EPSVPASC[160.03]AVSATYER[166.11].S "sp|Q92615|LAR4B_HUMAN,tr|H0Y641|H0Y641_HUMAN,tr|H0Y4V9|H0Y4V9_HUMAN" 3 1732.7966 1.31 65841 14020 2 1732.797605 867.4056 La-related protein 4B OS=Homo sapiens OX=9606 GN=LARP4B PE=1 SV=3 4.53 2581.6 - 257840 - - - 0.5973 - 2.051 0.664 - 140.3 1 2 0 0.001 16 0 0 0 2.59E+08 1.98E+08 - - - 5.711 0.9999 221125_WJC_METTL3_EV_vs_WT_F05.14021.14021.3 0.000235 Oct-64 K.FVSTTSQNTQLVRPPIR.S sp|Q8WWK9|CKAP2_HUMAN 1 1943.0589 0.77 65842 14021 3 1943.060259 648.6936 Cytoskeleton-associated protein 2 OS=Homo sapiens OX=9606 GN=CKAP2 PE=1 SV=1 12 2581.8 - 231324 - - - 0.7205 - 2.002 0.442 - 98.3 1 2 0 0.0014 17 0 0 0 1.07E+07 1.40E+07 - - - 5.2211 0.9996 221125_WJC_METTL3_EV_vs_WT_F05.14024.14024.3 0.0101 14/64 K.MAPVPLDDSNRPASLTK.D "sp|Q9NYF8|BCLF1_HUMAN,tr|E9PKI6|E9PKI6_HUMAN,tr|A0A1W2PQ43|A0A1W2PQ43_HUMAN,tr|E9PK91|E9PK91_HUMAN,tr|E9PJA7|E9PJA7_HUMAN,tr|E9PK09|E9PK09_HUMAN,tr|E9PQN2|E9PQN2_HUMAN" 7 1810.9247 1.88 65844 14024 3 1810.924615 604.6489 Bcl-2-associated transcription factor 1 OS=Homo sapiens OX=9606 GN=BCLAF1 PE=1 SV=2 5.71 2582.3 - 720761 - - - -0.0657 - 2.202 0.311 - 151.5 1 2 0 -0.0001 17 0 0 0 7.88E+06 4.19E+06 - - - 4.0015 1 221125_WJC_METTL3_EV_vs_WT_F05.14027.14027.2 2.87E-09 13/28 K.ELTVSNNDINEAGVR.V "sp|P13489|RINI_HUMAN,tr|E9PLZ3|E9PLZ3_HUMAN,tr|E9PMJ3|E9PMJ3_HUMAN,tr|E9PIM9|E9PIM9_HUMAN" 4 1629.7958 1.7 65846 14027 2 1629.797913 815.9052 Ribonuclease inhibitor OS=Homo sapiens OX=9606 GN=RNH1 PE=1 SV=2 4.14 2582.6 - 1.01E+06 - - - 1.2793 - 2.783 0.629 - 473.9 1 2 0 0.0021 15 0 0 0 4.79E+06 2.81E+06 - - - 6.2025 0.9999 221125_WJC_METTL3_EV_vs_WT_F05.14028.14028.2 7.12E-07 13/20 R.DAEDALHNLDR.K "sp|O75494|SRS10_HUMAN,tr|Q5JRI1|Q5JRI1_HUMAN" 2 1267.5793 1.67 65847 14028 2 1267.578822 634.7969 Serine\arginine-rich splicing factor 10 OS=Homo sapiens OX=9606 GN=SRSF10 PE=1 SV=1 4.22 2582.7 - 890086 - - - -0.3716 - 2.695 0.409 - 891.3 1 2 0 -0.0005 11 0 0 0 3.89E+06 2.33E+06 - - - 4.7437 0.9999 221125_WJC_METTL3_EV_vs_WT_F05.14029.14029.3 0.000275 Nov-36 K.NTWELK[136.11]PEYR[166.11].H sp|P13984|T2FB_HUMAN 1 1352.6844 1.18 65848 14029 3 1352.684313 451.9021 General transcription factor IIF subunit 2 OS=Homo sapiens OX=9606 GN=GTF2F2 PE=1 SV=2 6.14 2582.9 - 634235 - - - -0.0421 - 2.014 0.401 - 206.5 1 2 0 -0.0001 10 0 0 0 7.21E+06 6.12E+06 - - - 5.0554 0.9999 221125_WJC_METTL3_EV_vs_WT_F05.14030.14030.3 1.14E-05 15/72 K.FIGSPPGYVGHEEGGQLTK.K "sp|Q9H078|CLPB_HUMAN,tr|A0A2U3TZY2|A0A2U3TZY2_HUMAN,tr|H0YGM0|H0YGM0_HUMAN,tr|A0A2R8Y602|A0A2R8Y602_HUMAN" 4 1971.969 0.07 65849 14030 3 1971.972706 658.3303 Caseinolytic peptidase B protein homolog OS=Homo sapiens OX=9606 GN=CLPB PE=1 SV=1 5.4 2583 - 562075 - - - 1.8585 - 2.657 0.476 - 156 1 2 0 0.0037 19 0 0 0 4.10E+06 5.98E+07 - - - 6.2467 0.9999 221125_WJC_METTL3_EV_vs_WT_F05.14031.14031.2 1.82E-08 14/28 K.ELTVSNNDINEAGVR[166.11].V "sp|P13489|RINI_HUMAN,tr|E9PLZ3|E9PLZ3_HUMAN,tr|E9PMJ3|E9PMJ3_HUMAN,tr|E9PIM9|E9PIM9_HUMAN" 4 1639.8041 1.7 65850 14031 2 1639.80418 820.9093 Ribonuclease inhibitor OS=Homo sapiens OX=9606 GN=RNH1 PE=1 SV=2 4.14 2583.1 - 556281 - - - 0.05 - 2.569 0.569 - 592.8 1 2 0 0.0001 15 0 0 0 4.79E+06 2.81E+06 - - - 5.5633 0.9997 221125_WJC_METTL3_EV_vs_WT_F05.14032.14032.3 7.59E-05 16/48 K.SALVK[136.11]PVTINVGR[166.11].A sp|Q9UJV9|DDX41_HUMAN 1 1370.8365 0.88 65851 14032 3 1370.843306 457.9528 Probable ATP-dependent RNA helicase DDX41 OS=Homo sapiens OX=9606 GN=DDX41 PE=1 SV=2 11 2583.2 - 518543 - - - 4.9984 - 2.952 0.495 - 316.2 1 2 0 0.0069 13 0 0 0 4.46E+06 5.07E+06 - - - 6.9918 0.9978 221125_WJC_METTL3_EV_vs_WT_F05.14033.14033.3 3.33E-06 13/56 R.VVGC[160.03]EGSSKPFFYNR.Q "sp|Q709C8|VP13C_HUMAN,tr|A0A3B3IU50|A0A3B3IU50_HUMAN" 2 1745.8195 0.93 65852 14033 3 1745.813608 582.9471 Vacuolar protein sorting-associated protein 13C OS=Homo sapiens OX=9606 GN=VPS13C PE=1 SV=1 8.17 2583.4 - 467776 - - - -3.3978 - 2.255 0.293 - 167.4 1 2 0 -0.0059 15 0 0 0 2.79E+06 3.01E+06 - - - 3.9268 0.9997 221125_WJC_METTL3_EV_vs_WT_F05.14034.14034.2 4.15E-05 22-Oct R.AQPSVSLGAPYR.G sp|Q96PK6|RBM14_HUMAN 1 1244.6513 2.35 65853 14034 2 1244.651596 623.3329 RNA-binding protein 14 OS=Homo sapiens OX=9606 GN=RBM14 PE=1 SV=2 8.79 2583.5 - 404855 - - - 0.2089 - 2.178 0.34 - 382.9 1 2 0 0.0003 12 0 0 0 1.14E+07 4.85E+06 - - - 3.6003 1 221125_WJC_METTL3_EV_vs_WT_F05.14035.14035.2 4.63E-08 18/32 R.AVDLVEEESGAPGEEQR.R "sp|O60231|DHX16_HUMAN,tr|A0A140T947|A0A140T947_HUMAN,tr|A2AB15|A2AB15_HUMAN" 3 1813.833 2 65854 14035 2 1813.828604 907.9238 Pre-mRNA-splicing factor ATP-dependent RNA helicase DHX16 OS=Homo sapiens OX=9606 GN=DHX16 PE=1 SV=2 3.83 2583.6 - 400991 - - - -2.4241 - 3.476 0.677 - 961.5 1 2 0 -0.0044 17 0 0 0 8.13E+06 4.06E+06 - - - 7.103 1 221125_WJC_METTL3_EV_vs_WT_F05.14037.14037.2 1.11E-05 17/26 K.GPSGC[160.03]VESLEVTC[160.03]R[166.11].R "sp|P47897|SYQ_HUMAN,tr|B4DDN1|B4DDN1_HUMAN,tr|H7C0R3|H7C0R3_HUMAN,tr|A0A0U1RQX5|A0A0U1RQX5_HUMAN,tr|A0A1B0GVU9|A0A1B0GVU9_HUMAN,tr|A0A0U1RQX9|A0A0U1RQX9_HUMAN" 6 1559.6947 0.36 65856 14037 2 1559.696998 780.8547 Glutamine--tRNA ligase OS=Homo sapiens OX=9606 GN=QARS1 PE=1 SV=1 4.53 2583.9 - 391089 - - - 1.4426 - 3.154 0.68 - 1242.6 1 2 0 0.0022 14 0 0 0 1.16E+06 3.26E+06 - - - 6.9453 1 221125_WJC_METTL3_EV_vs_WT_F05.14041.14041.2 6.27E-09 17/32 R.AVDLVEEESGAPGEEQR[166.11].R "sp|O60231|DHX16_HUMAN,tr|A0A140T947|A0A140T947_HUMAN,tr|A2AB15|A2AB15_HUMAN" 3 1823.8413 2 65860 14041 2 1823.844049 912.9279 Pre-mRNA-splicing factor ATP-dependent RNA helicase DHX16 OS=Homo sapiens OX=9606 GN=DHX16 PE=1 SV=2 3.83 2584.4 - 281263 - - - 1.5232 - 3.278 0.677 - 871 1 2 0 0.0028 17 0 0 0 8.13E+06 4.06E+06 - - - 6.9593 1 221125_WJC_METTL3_EV_vs_WT_F05.14044.14044.2 1.02E-05 22-Oct K.SEVSSDEDIQFR[166.11].L "sp|P40939|ECHA_HUMAN,tr|H0YFD6|H0YFD6_HUMAN,tr|A0A2R8Y4F5|A0A2R8Y4F5_HUMAN" 3 1420.6346 0.58 65863 14044 2 1420.634459 711.3246 "Trifunctional enzyme subunit alpha, mitochondrial OS=Homo sapiens OX=9606 GN=HADHA PE=1 SV=2" 3.92 2584.8 - 213216 - - - -0.0802 - 2.381 0.652 - 294.4 1 2 0 -0.0001 12 0 0 0 8.05E+05 1.39E+06 - - - 6.1392 0.9997 221125_WJC_METTL3_EV_vs_WT_F05.14049.14049.3 0.000199 Nov-36 K.NYGFVHIEDK.T "sp|Q9BWF3|RBM4_HUMAN,sp|Q9BQ04|RBM4B_HUMAN,tr|E9PM61|E9PM61_HUMAN,tr|D6R9K7|D6R9K7_HUMAN,tr|J3QRR5|J3QRR5_HUMAN,tr|E9PB51|E9PB51_HUMAN,tr|U3KQD5|U3KQD5_HUMAN,tr|E9PLB0|E9PLB0_HUMAN" 8 1220.5826 1.5 65867 14049 3 1220.583027 407.8681 RNA-binding protein 4 OS=Homo sapiens OX=9606 GN=RBM4 PE=1 SV=1 5.32 2585.3 - 4.28E+06 - - - 0.3597 - 2.327 0.285 - 272.3 1 2 0 0.0004 10 0 0 0 7.65E+07 5.10E+07 - - - 4.1839 1 221125_WJC_METTL3_EV_vs_WT_F05.14050.14050.2 3.33E-05 14/20 R.QGVDADINGLR.Q "sp|P35527|K1C9_HUMAN,tr|K7EQQ3|K7EQQ3_HUMAN" 2 1156.5837 329.45 65868 14050 2 1156.584127 579.2991 "Keratin, type I cytoskeletal 9 OS=Homo sapiens OX=9606 GN=KRT9 PE=1 SV=3" 4.21 2585.4 - 3.85E+06 - - - 0.4124 - 2.717 0.562 - 1164.3 1 2 0 0.0005 11 0 0 0 3.52E+07 1.07E+05 - - - 5.8957 1 221125_WJC_METTL3_EV_vs_WT_F05.14051.14051.3 9.53E-07 14/48 R.VKPLQDQNELFGK.L sp|Q12874|SF3A3_HUMAN 1 1514.8093 4.13 65869 14051 3 1514.81044 505.9437 Splicing factor 3A subunit 3 OS=Homo sapiens OX=9606 GN=SF3A3 PE=1 SV=1 6.04 2585.4 - 3.14E+06 - - - 0.7572 - 2.233 0.513 - 162.7 1 2 0 0.0011 13 0 0 0 2.24E+08 5.44E+07 - - - 6.4372 0.9998 221125_WJC_METTL3_EV_vs_WT_F05.14052.14052.3 5.97E-05 Oct-36 K.NYGFVHIEDK[136.11].T "sp|Q9BWF3|RBM4_HUMAN,sp|Q9BQ04|RBM4B_HUMAN,tr|E9PM61|E9PM61_HUMAN,tr|D6R9K7|D6R9K7_HUMAN,tr|J3QRR5|J3QRR5_HUMAN,tr|E9PB51|E9PB51_HUMAN,tr|U3KQD5|U3KQD5_HUMAN,tr|E9PLB0|E9PLB0_HUMAN" 8 1228.5968 1.5 65870 14052 3 1228.597065 410.5395 RNA-binding protein 4 OS=Homo sapiens OX=9606 GN=RBM4 PE=1 SV=1 5.32 2585.5 - 3.13E+06 - - - 0.2255 - 2.175 0.323 - 201.7 1 2 0 0.0003 10 0 0 0 7.65E+07 5.10E+07 - - - 4.4103 1 221125_WJC_METTL3_EV_vs_WT_F05.14054.14054.3 2.47E-07 Oct-44 K.LSGHQFENYSFK.L "sp|Q9Y6M1|IF2B2_HUMAN,tr|F8W930|F8W930_HUMAN" 2 1455.6783 1.36 65872 14054 3 1455.67937 486.2334 Insulin-like growth factor 2 mRNA-binding protein 2 OS=Homo sapiens OX=9606 GN=IGF2BP2 PE=1 SV=2 6.75 2585.6 - 2.20E+06 - - - 0.7495 - 2.436 0.536 - 131.3 1 2 0 0.0011 12 0 0 0 2.93E+07 2.16E+07 - - - 6.9835 1 221125_WJC_METTL3_EV_vs_WT_F05.14055.14055.3 2.38E-06 13/44 K.LSGHQFENYSFK[136.11].L "sp|Q9Y6M1|IF2B2_HUMAN,tr|F8W930|F8W930_HUMAN" 2 1463.6925 1.39 65873 14055 3 1463.693394 488.9048 Insulin-like growth factor 2 mRNA-binding protein 2 OS=Homo sapiens OX=9606 GN=IGF2BP2 PE=1 SV=2 6.75 2585.7 - 1.84E+06 - - - 0.6251 - 2.677 0.564 - 230.2 1 2 0 0.0009 12 0 0 0 2.93E+07 2.11E+07 - - - 7.5572 1 221125_WJC_METTL3_EV_vs_WT_F05.14056.14056.3 5.26E-07 14/44 K.ITVTSEVPFSK[136.11]R[166.11].Y "sp|P35268|RL22_HUMAN,tr|K7EKS7|K7EKS7_HUMAN,tr|K7ERI7|K7ERI7_HUMAN,tr|K7EMH1|K7EMH1_HUMAN,tr|K7ELC4|K7ELC4_HUMAN,tr|K7EP65|K7EP65_HUMAN" 6 1380.7732 0.69 65874 14056 3 1380.773819 461.265 60S ribosomal protein L22 OS=Homo sapiens OX=9606 GN=RPL22 PE=1 SV=2 8.75 2585.8 - 1.79E+06 - - - 0.4584 - 2.868 0.428 - 266.1 1 2 0 0.0006 12 0 0 0 1.78E+07 2.57E+07 - - - 6.2321 1 221125_WJC_METTL3_EV_vs_WT_F05.14058.14058.3 1.44E-06 13/48 R.VK[136.11]PLQDQNELFGK[136.11].L sp|Q12874|SF3A3_HUMAN 1 1530.8377 4.11 65876 14058 3 1530.839597 511.2865 Splicing factor 3A subunit 3 OS=Homo sapiens OX=9606 GN=SF3A3 PE=1 SV=1 6.04 2585.9 - 972204 - - - 1.2438 - 2.282 0.5 - 136 1 2 0 0.0019 13 0 0 0 2.24E+08 5.47E+07 - - - 6.3509 1 221125_WJC_METTL3_EV_vs_WT_F05.14060.14060.2 4.18E-10 15/26 K.GPSGC[160.03]VESLEVTC[160.03]R.R "sp|P47897|SYQ_HUMAN,tr|B4DDN1|B4DDN1_HUMAN,tr|H7C0R3|H7C0R3_HUMAN,tr|A0A0U1RQX5|A0A0U1RQX5_HUMAN,tr|A0A1B0GVU9|A0A1B0GVU9_HUMAN,tr|A0A0U1RQX9|A0A0U1RQX9_HUMAN" 6 1549.6865 -1 65878 14060 2 1549.698286 775.8505 Glutamine--tRNA ligase OS=Homo sapiens OX=9606 GN=QARS1 PE=1 SV=1 4.53 2586.1 - 786083 - - - 7.6196 - 2.902 0.706 - 788.5 1 2 0 0.0118 14 0 0 0 0.00E+00 0.00E+00 - - - 6.9254 0.9996 221125_WJC_METTL3_EV_vs_WT_F05.14061.14061.3 0.000447 13/56 K.EGEDMIAEEHFGSEK.L "sp|Q01082|SPTB2_HUMAN,tr|A0A087WUZ3|A0A087WUZ3_HUMAN" 2 1706.7094 2.08 65879 14061 3 1706.713333 569.9104 "Spectrin beta chain, non-erythrocytic 1 OS=Homo sapiens OX=9606 GN=SPTBN1 PE=1 SV=2" 4.14 2586.3 - 778878 - - - 2.3156 - 2.424 0.341 - 245.4 1 2 0 0.004 15 0 0 0 3.80E+06 1.83E+06 - - - 4.6511 0.9999 221125_WJC_METTL3_EV_vs_WT_F05.14062.14062.3 7.69E-06 14/64 R.AVDLVEEESGAPGEEQR.R "sp|O60231|DHX16_HUMAN,tr|A0A140T947|A0A140T947_HUMAN,tr|A2AB15|A2AB15_HUMAN" 3 1813.833 1.48 65880 14062 3 1813.829701 605.6183 Pre-mRNA-splicing factor ATP-dependent RNA helicase DHX16 OS=Homo sapiens OX=9606 GN=DHX16 PE=1 SV=2 3.83 2586.4 - 757651 - - - -1.8194 - 2.535 0.405 - 217.1 1 2 0 -0.0033 17 0 0 0 4.77E+06 3.21E+06 - - - 5.4044 1 221125_WJC_METTL3_EV_vs_WT_F05.14063.14063.2 7.93E-06 17/26 K.NVTELNEPLSNEER[166.11].N sp|P61981|1433G_HUMAN 1 1652.7881 1.24 65881 14063 2 1652.789328 827.4013 14-3-3 protein gamma OS=Homo sapiens OX=9606 GN=YWHAG PE=1 SV=2 4.09 2586.5 - 697408 - - - 0.7351 - 3.397 0.574 - 922.2 1 2 0 0.0012 14 0 0 0 2.37E+07 1.91E+07 - - - 6.349 0.9999 221125_WJC_METTL3_EV_vs_WT_F05.14064.14064.3 0.000496 13/44 R.TATGLTHIIETR[166.11].K sp|Q709C8|VP13C_HUMAN 1 1321.7229 1.25 65882 14064 3 1321.723618 441.5816 Vacuolar protein sorting-associated protein 13C OS=Homo sapiens OX=9606 GN=VPS13C PE=1 SV=1 6.41 2586.6 - 574228 - - - 0.5175 - 2.599 0.399 - 284.1 1 2 0 0.0007 12 0 0 0 2.94E+06 2.35E+06 - - - 5.6357 1 221125_WJC_METTL3_EV_vs_WT_F05.14065.14065.3 1.51E-06 Dec-64 K.FVSTTSQNTQLVR[166.11]PPIR[166.11].S sp|Q8WWK9|CKAP2_HUMAN 1 1963.0754 0.79 65883 14065 3 1963.07559 655.3657 Cytoskeleton-associated protein 2 OS=Homo sapiens OX=9606 GN=CKAP2 PE=1 SV=1 12 2586.8 - 548174 - - - 0.0973 - 2.166 0.556 - 124.8 1 2 0 0.0002 17 0 0 0 1.01E+07 1.27E+07 - - - 6.6913 1 221125_WJC_METTL3_EV_vs_WT_F05.14068.14068.2 5.29E-11 18/32 R.GLGVGFGSGGGSSSSVK.F sp|P13647|K2C5_HUMAN 1 1438.7052 999 65885 14068 2 1438.707262 720.3599 "Keratin, type II cytoskeletal 5 OS=Homo sapiens OX=9606 GN=KRT5 PE=1 SV=3" 8.75 2587.3 - 974805 - - - 1.4179 - 3.191 0.672 - 1012.7 1 2 0 0.002 17 0 0 0 4.31E+07 0.00E+00 - - - 6.8565 1 221125_WJC_METTL3_EV_vs_WT_F05.14069.14069.3 1.06E-08 14/48 K.SHLEVPLEENVNR[166.11].R "sp|Q96CT7|CC124_HUMAN,tr|M0R2F5|M0R2F5_HUMAN" 2 1544.7822 0.44 65886 14069 3 1544.781617 515.9347 Coiled-coil domain-containing protein 124 OS=Homo sapiens OX=9606 GN=CCDC124 PE=1 SV=1 4.75 2587.4 - 328581 - - - -0.4033 - 2.709 0.513 - 371.7 1 2 0 -0.0006 13 0 0 0 1.29E+06 2.96E+06 - - - 6.9613 1 221125_WJC_METTL3_EV_vs_WT_F05.14070.14070.3 8.13E-09 17/60 R.GITINAAHVEYSTAAR.H sp|P49411|EFTU_HUMAN 1 1672.8533 1.57 65887 14070 3 1672.855612 558.625 "Elongation factor Tu, mitochondrial OS=Homo sapiens OX=9606 GN=TUFM PE=1 SV=2" 6.75 2587.4 - 4.46E+06 - - - 1.3922 - 3.353 0.562 - 322.2 1 2 0 0.0023 16 0 0 0 1.39E+08 8.82E+07 - - - 7.9094 0.9996 221125_WJC_METTL3_EV_vs_WT_F05.14072.14072.3 0.00596 Nov-48 K.SALVKPVTINVGR.A sp|Q9UJV9|DDX41_HUMAN 1 1352.814 0.88 65889 14072 3 1352.815651 451.9453 Probable ATP-dependent RNA helicase DDX41 OS=Homo sapiens OX=9606 GN=DDX41 PE=1 SV=2 11 2587.6 - 1.11E+06 - - - 1.2322 - 1.991 0.333 - 170.4 1 2 0 0.0017 13 0 0 0 4.46E+06 5.07E+06 - - - 4.1193 1 221125_WJC_METTL3_EV_vs_WT_F05.14073.14073.2 2.07E-16 18/36 R.FGIVTSSAGTGTTEDTEAK[136.11].K "sp|P82979|SARNP_HUMAN,tr|H0YHG0|H0YHG0_HUMAN" 2 1878.8938 0.64 65890 14073 2 1878.894981 940.4542 SAP domain-containing ribonucleoprotein OS=Homo sapiens OX=9606 GN=SARNP PE=1 SV=3 4.14 2587.7 - 1.01E+06 - - - 0.6195 - 3.7 0.741 - 917.8 1 2 0 0.0012 19 0 0 0 1.19E+07 1.86E+07 - - - 7.7303 1 221125_WJC_METTL3_EV_vs_WT_F05.14074.14074.2 7.81E-17 19/36 R.FGIVTSSAGTGTTEDTEAK.K "sp|P82979|SARNP_HUMAN,tr|H0YHG0|H0YHG0_HUMAN" 2 1870.8796 0.64 65891 14074 2 1870.881458 936.4471 SAP domain-containing ribonucleoprotein OS=Homo sapiens OX=9606 GN=SARNP PE=1 SV=3 4.14 2587.8 - 607562 - - - 0.984 - 3.95 0.749 - 1121.6 1 2 0 0.0018 19 0 0 0 1.19E+07 1.86E+07 - - - 7.9499 0.9997 221125_WJC_METTL3_EV_vs_WT_F05.14082.14082.2 0.000165 24-Aug R.VK[136.11]PLQDQNELFGK[136.11].L sp|Q12874|SF3A3_HUMAN 1 1530.8377 4.14 65899 14082 2 1530.837358 766.4261 Splicing factor 3A subunit 3 OS=Homo sapiens OX=9606 GN=SF3A3 PE=1 SV=1 6.04 2588.9 - 234705 - - - -0.2188 - 1.669 0.431 - 116.4 1 2 0 -0.0003 13 0 0 0 1.95E+07 4.72E+06 - - - 3.5389 0.9975 221125_WJC_METTL3_EV_vs_WT_F05.14088.14088.2 0.694 18-Jul K.NYGFVHIEDK[136.11].T "sp|Q9BWF3|RBM4_HUMAN,sp|Q9BQ04|RBM4B_HUMAN,tr|E9PM61|E9PM61_HUMAN,tr|D6R9K7|D6R9K7_HUMAN,tr|J3QRR5|J3QRR5_HUMAN,tr|E9PB51|E9PB51_HUMAN,tr|U3KQD5|U3KQD5_HUMAN,tr|E9PLB0|E9PLB0_HUMAN" 8 1228.5968 0.95 65903 14088 2 1228.597163 615.3057 RNA-binding protein 4 OS=Homo sapiens OX=9606 GN=RBM4 PE=1 SV=1 5.32 2589.5 - 1.59E+06 - - - 0.3052 - 1.209 0.279 - 93.1 1 2 0 0.0004 10 0 0 0 1.59E+07 1.67E+07 - - - 1.6313 1 221125_WJC_METTL3_EV_vs_WT_F05.14092.14092.3 6.75E-07 Nov-44 K.FIC[160.03]EQDHQNFLR[166.11].L "sp|Q92598|HS105_HUMAN,tr|A0A0A0MSM0|A0A0A0MSM0_HUMAN" 2 1615.7441 0.12 65907 14092 3 1615.744601 539.5886 Heat shock protein 105 kDa OS=Homo sapiens OX=9606 GN=HSPH1 PE=1 SV=1 5.32 2589.9 - 852783 - - - 0.3218 - 2.445 0.564 - 94.9 1 2 0 0.0005 12 0 0 0 6.26E+05 5.03E+06 - - - 7.3061 0.9999 221125_WJC_METTL3_EV_vs_WT_F05.14093.14093.3 2.83E-05 16/48 K.QYLPNVK[136.11]PDSSFK[136.11].L sp|Q8N766|EMC1_HUMAN 1 1537.8111 1.46 65908 14093 3 1537.807621 513.611 ER membrane protein complex subunit 1 OS=Homo sapiens OX=9606 GN=EMC1 PE=1 SV=1 8.5 2590 - 814646 - - - -2.2909 - 2.377 0.477 - 222.7 1 2 0 -0.0035 13 0 0 0 7.79E+06 5.33E+06 - - - 6.2046 1 221125_WJC_METTL3_EV_vs_WT_F05.14095.14095.2 1.71E-10 16/30 R.GITINAAHVEYSTAAR.H sp|P49411|EFTU_HUMAN 1 1672.8533 1.18 65910 14095 2 1672.859767 837.4339 "Elongation factor Tu, mitochondrial OS=Homo sapiens OX=9606 GN=TUFM PE=1 SV=2" 6.75 2590.2 - 683200 - - - 3.876 - 3.041 0.564 - 786.5 1 2 0 0.0065 16 0 0 0 6.12E+06 5.21E+06 - - - 5.939 0.9999 221125_WJC_METTL3_EV_vs_WT_F05.14097.14097.2 2.03E-05 22-Nov R.AQVQEFC[160.03]DYGTK[136.11].E "sp|Q86U44|MTA70_HUMAN,tr|H0YFV6|H0YFV6_HUMAN" 2 1452.6435 0.01 65912 14097 2 1452.643196 727.329 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 4.37 2590.5 - 510005 - - - -0.1955 - 2.498 0.502 - 357.5 1 2 0 -0.0003 12 0 0 0 8.75E+04 7.31E+06 - - - 5.1575 1 221125_WJC_METTL3_EV_vs_WT_F05.14098.14098.3 0.000157 24/76 R.LQQQAALSPTTAPAVSSVSK[136.11].Q "sp|Q8WXI9|P66B_HUMAN,tr|A0A0U1RRM1|A0A0U1RRM1_HUMAN,tr|A0A0U1RR30|A0A0U1RR30_HUMAN" 3 1991.0779 1.39 65913 14098 3 1991.078081 664.6999 Transcriptional repressor p66-beta OS=Homo sapiens OX=9606 GN=GATAD2B PE=1 SV=1 8.75 2590.6 - 468208 - - - 0.106 - 3.662 0.495 - 545.7 1 2 0 0.0002 20 0 0 0 8.57E+06 6.15E+06 - - - 7.2077 0.9997 221125_WJC_METTL3_EV_vs_WT_F05.14099.14099.3 1.84E-05 15/48 R.LSTKDPLPTIASR.E "sp|Q9BZE1|RM37_HUMAN,tr|S4R369|S4R369_HUMAN,tr|H0Y4J2|H0Y4J2_HUMAN,tr|A6NHR2|A6NHR2_HUMAN" 4 1397.7878 1.04 65914 14099 3 1397.7898 466.9366 "39S ribosomal protein L37, mitochondrial OS=Homo sapiens OX=9606 GN=MRPL37 PE=1 SV=2" 8.75 2590.7 - 415552 - - - 1.4101 - 2.867 0.421 - 313.1 1 2 1 0.002 13 0 0 0 1.04E+07 9.98E+06 - - - 6.0889 1 221125_WJC_METTL3_EV_vs_WT_F05.14100.14100.2 5.80E-10 14/30 K.TLLVSTSAVDNNEAQK[136.11].K "sp|Q5T8P6|RBM26_HUMAN,tr|A0A087X0H9|A0A087X0H9_HUMAN" 2 1696.8723 1.04 65915 14100 2 1696.871799 849.4434 RNA-binding protein 26 OS=Homo sapiens OX=9606 GN=RBM26 PE=1 SV=3 4.37 2590.8 - 283516 - - - -0.2917 - 2.865 0.715 - 438.2 1 2 0 -0.0005 16 0 0 0 8.95E+06 8.58E+06 - - - 6.9096 0.9991 221125_WJC_METTL3_EV_vs_WT_F05.14102.14102.2 0.000425 22-Jun K.ITVTSEVPFSK[136.11]R[166.11].Y "sp|P35268|RL22_HUMAN,tr|K7EKS7|K7EKS7_HUMAN,tr|K7ERI7|K7ERI7_HUMAN,tr|K7EMH1|K7EMH1_HUMAN,tr|K7ELC4|K7ELC4_HUMAN,tr|K7EP65|K7EP65_HUMAN" 6 1380.7732 0.91 65917 14102 2 1380.775415 691.3939 60S ribosomal protein L22 OS=Homo sapiens OX=9606 GN=RPL22 PE=1 SV=2 8.75 2591.1 - 232524 - - - 1.6143 - 1.332 0.435 - 70.9 1 2 0 0.0022 12 0 0 0 9.78E+05 1.08E+06 - - - 3.0075 1 221125_WJC_METTL3_EV_vs_WT_F05.14103.14103.2 1.13E-08 13/38 R.LQQQAALSPTTAPAVSSVSK.Q "sp|Q8WXI9|P66B_HUMAN,tr|A0A0U1RRM1|A0A0U1RRM1_HUMAN,tr|A0A0U1RR30|A0A0U1RR30_HUMAN" 3 1983.0637 3.51 65918 14103 2 1983.064765 992.5391 Transcriptional repressor p66-beta OS=Homo sapiens OX=9606 GN=GATAD2B PE=1 SV=1 8.75 2591.2 - 134437 - - - 0.5522 - 2.747 0.601 - 422.8 1 2 0 0.0011 20 0 0 0 2.68E+06 7.65E+05 - - - 5.964 1 221125_WJC_METTL3_EV_vs_WT_F05.14107.14107.3 1.21E-08 19/52 K.TIDLGAAAHYTGDK.A sp|Q14677|EPN4_HUMAN 1 1431.6994 1.6 65921 14107 3 1431.70111 478.2404 Clathrin interactor 1 OS=Homo sapiens OX=9606 GN=CLINT1 PE=1 SV=1 5.18 2591.6 - 2.34E+06 - - - 1.1888 - 3.708 0.577 - 331.5 1 2 0 0.0017 14 0 0 0 3.38E+08 2.11E+08 - - - 8.4552 0.9981 221125_WJC_METTL3_EV_vs_WT_F05.14108.14108.2 0.0492 24-Sep R.VKPLQDQNELFGK.L sp|Q12874|SF3A3_HUMAN 1 1514.8093 4.14 65922 14108 2 1514.810121 758.4119 Splicing factor 3A subunit 3 OS=Homo sapiens OX=9606 GN=SF3A3 PE=1 SV=1 6.04 2591.7 - 2.28E+06 - - - 0.5466 - 1.567 0.231 - 137.9 1 2 0 0.0008 13 0 0 0 1.95E+07 4.72E+06 - - - 1.8997 1 221125_WJC_METTL3_EV_vs_WT_F05.14109.14109.3 4.74E-06 17/48 K.QYLPNVKPDSSFK.L sp|Q8N766|EMC1_HUMAN 1 1521.7827 0.91 65923 14109 3 1521.783329 508.2682 ER membrane protein complex subunit 1 OS=Homo sapiens OX=9606 GN=EMC1 PE=1 SV=1 8.5 2591.7 - 1.64E+06 - - - 0.3844 - 2.398 0.482 - 320 1 2 0 0.0006 13 0 0 0 9.16E+06 1.01E+07 - - - 6.2851 0.9999 221125_WJC_METTL3_EV_vs_WT_F05.14110.14110.3 8.50E-06 13/44 K.LKEYEAAVEQLK.S "sp|Q5T9A4|ATD3B_HUMAN,tr|H0Y2W2|H0Y2W2_HUMAN" 2 1419.7609 1.43 65924 14110 3 1419.762239 474.2609 ATPase family AAA domain-containing protein 3B OS=Homo sapiens OX=9606 GN=ATAD3B PE=1 SV=1 4.79 2591.8 - 1.08E+06 - - - 0.9107 - 2.649 0.495 - 351.3 1 2 1 0.0013 12 0 0 0 1.31E+07 9.17E+06 - - - 6.7587 1 221125_WJC_METTL3_EV_vs_WT_F05.14114.14114.2 1.44E-11 15/30 K.TLLVSTSAVDNNEAQK.K "sp|Q5T8P6|RBM26_HUMAN,tr|A0A087X0H9|A0A087X0H9_HUMAN" 2 1688.8581 1.04 65928 14114 2 1688.859365 845.4363 RNA-binding protein 26 OS=Homo sapiens OX=9606 GN=RBM26 PE=1 SV=3 4.37 2592.2 - 732789 - - - 0.7526 - 3.277 0.666 - 528.8 1 2 0 0.0013 16 0 0 0 8.95E+06 8.58E+06 - - - 6.8778 0.9988 221125_WJC_METTL3_EV_vs_WT_F05.14116.14116.3 6.29E-08 19/60 A.GGVVNSALYNVDAGHR.A "sp|P35232|PHB_HUMAN,tr|E7ESE2|E7ESE2_HUMAN,tr|E9PCW0|E9PCW0_HUMAN,tr|C9JW96|C9JW96_HUMAN" 4 1627.8067 1.65 65930 14116 3 1627.808258 543.6095 Prohibitin OS=Homo sapiens OX=9606 GN=PHB PE=1 SV=1 6.74 2592.5 - 536565 - - - 0.9774 - 3.099 0.599 - 565.3 1 1 0 0.0016 16 0 0 0 8.85E+06 5.37E+06 - - - 8.12 1 221125_WJC_METTL3_EV_vs_WT_F05.14121.14121.2 1.74E-08 13/32 K.AAC[160.03]LESAQEPAGAWGNK[136.11].L "tr|C9JHZ8|C9JHZ8_HUMAN,tr|C9JHN6|C9JHN6_HUMAN,tr|C9JZI8|C9JZI8_HUMAN,tr|C9JT62|C9JT62_HUMAN,tr|A0A024R4E5|A0A024R4E5_HUMAN,tr|C9JEJ8|C9JEJ8_HUMAN,tr|C9JIZ1|C9JIZ1_HUMAN,tr|C9JBS3|C9JBS3_HUMAN,tr|C9JES8|C9JES8_HUMAN,tr|C9J5E5|C9J5E5_HUMAN,tr|C9JK79|C9JK79_HUMAN,tr|C9JHS7|C9JHS7_HUMAN" 12 1766.8137 1.36 65935 14121 2 1766.810762 884.4141 Vigilin (Fragment) OS=Homo sapiens OX=9606 GN=HDLBP PE=1 SV=2 4.53 2593.1 - 378304 - - - -1.6816 - 2.595 0.681 - 432.3 1 2 0 -0.003 17 0 0 0 4.40E+06 3.23E+06 - - - 6.4144 1 221125_WJC_METTL3_EV_vs_WT_F05.14122.14122.2 3.06E-11 17/32 K.AAC[160.03]LESAQEPAGAWGNK.L "tr|C9JHZ8|C9JHZ8_HUMAN,tr|C9JHN6|C9JHN6_HUMAN,tr|C9JZI8|C9JZI8_HUMAN,tr|C9JT62|C9JT62_HUMAN,tr|A0A024R4E5|A0A024R4E5_HUMAN,tr|C9JEJ8|C9JEJ8_HUMAN,tr|C9JIZ1|C9JIZ1_HUMAN,tr|C9JBS3|C9JBS3_HUMAN,tr|C9JES8|C9JES8_HUMAN,tr|C9J5E5|C9J5E5_HUMAN,tr|C9JK79|C9JK79_HUMAN,tr|C9JHS7|C9JHS7_HUMAN" 12 1758.7995 1.36 65936 14122 2 1758.801179 880.407 Vigilin (Fragment) OS=Homo sapiens OX=9606 GN=HDLBP PE=1 SV=2 4.53 2593.3 - 311664 - - - 0.9359 - 3.124 0.705 - 849.5 1 2 0 0.0016 17 0 0 0 4.40E+06 3.23E+06 - - - 7.0482 0.9956 221125_WJC_METTL3_EV_vs_WT_F05.14123.14123.3 0.0253 Sep-40 K.K[136.11]FEEIPIAHIK[136.11].A "sp|P82912|RT11_HUMAN,tr|H0YL99|H0YL99_HUMAN" 2 1339.7835 2.09 65937 14123 3 1339.78839 447.6018 "28S ribosomal protein S11, mitochondrial OS=Homo sapiens OX=9606 GN=MRPS11 PE=1 SV=2" 6.76 2593.4 - 311576 - - - 3.67 - 1.921 0.285 - 128.8 1 2 0 0.0049 11 0 0 0 6.94E+06 3.32E+06 - - - 3.5707 1 221125_WJC_METTL3_EV_vs_WT_F05.14130.14130.3 7.52E-08 13/40 R.GNDVAFHFNPR.F "sp|P17931|LEG3_HUMAN,tr|G3V3R6|G3V3R6_HUMAN" 2 1272.6 52.66 65942 14130 3 1272.599679 425.2073 Galectin-3 OS=Homo sapiens OX=9606 GN=LGALS3 PE=1 SV=5 6.74 2594.2 - 985393 - - - -0.2279 - 2.634 0.533 - 348.8 1 2 0 -0.0003 11 0 0 0 1.02E+07 1.94E+05 - - - 7.2337 0.9979 221125_WJC_METTL3_EV_vs_WT_F05.14133.14133.2 0.275 Apr-32 R.TAGPLESSETEEASQLK[136.11].E "sp|Q9P2E9|RRBP1_HUMAN,tr|A0A087WU26|A0A087WU26_HUMAN,tr|A0A087WVV2|A0A087WVV2_HUMAN,tr|F8W7S5|F8W7S5_HUMAN" 4 1783.8567 2.26 65945 14133 2 1783.860025 892.9356 Ribosome-binding protein 1 OS=Homo sapiens OX=9606 GN=RRBP1 PE=1 SV=5 4.09 2594.6 - 126454 - - - 1.8623 - 1.188 0.412 - 31.9 2 2 0 0.0033 17 0 0 0 3.27E+07 1.45E+07 - - - 2.3721 0.9899 221125_WJC_METTL3_EV_vs_WT_F05.14137.14137.2 2.01E-06 24-Jul R.R[166.11]AEQDSTTVAAFA.S "sp|Q86U44|MTA70_HUMAN,tr|F5H6D8|F5H6D8_HUMAN,tr|H0YFV6|H0YFV6_HUMAN,tr|B4DTN4|B4DTN4_HUMAN" 4 1375.6607 0.03 65947 14137 2 1375.661933 688.8376 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 4.37 2595.2 - 3.19E+06 - - - 0.8759 - 1.774 0.562 - 99.7 1 1 0 0.0012 13 0 0 0 1.34E+06 4.28E+07 - - - 4.6628 0.9999 221125_WJC_METTL3_EV_vs_WT_F05.14140.14140.3 1.07E-07 19/76 R.LQQQAALSPTTAPAVSSVSK.Q "sp|Q8WXI9|P66B_HUMAN,tr|A0A0U1RRM1|A0A0U1RRM1_HUMAN,tr|A0A0U1RR30|A0A0U1RR30_HUMAN" 3 1983.0637 1.39 65950 14140 3 1983.068728 662.0285 Transcriptional repressor p66-beta OS=Homo sapiens OX=9606 GN=GATAD2B PE=1 SV=1 8.75 2595.4 - 1.22E+06 - - - 2.5506 - 2.803 0.484 - 314 1 2 0 0.0051 20 0 0 0 8.57E+06 6.15E+06 - - - 6.4352 1 221125_WJC_METTL3_EV_vs_WT_F05.14141.14141.3 2.34E-07 16/68 R.SPLLAGGSPPQPVVPAHK.D "sp|Q8NFH5|NUP35_HUMAN,tr|F8WCF5|F8WCF5_HUMAN,tr|F8WEL4|F8WEL4_HUMAN,tr|C9JIY9|C9JIY9_HUMAN,tr|C9IYQ7|C9IYQ7_HUMAN" 5 1750.973 2.11 65951 14141 3 1750.974305 584.6649 Nucleoporin NUP35 OS=Homo sapiens OX=9606 GN=NUP35 PE=1 SV=1 8.49 2595.5 - 897042 - - - 0.743 - 3.146 0.543 - 305.3 1 2 0 0.0013 18 0 0 0 1.83E+07 8.68E+06 - - - 7.4475 1 221125_WJC_METTL3_EV_vs_WT_F05.14143.14143.3 4.66E-07 15/44 R.R[166.11]IPWTAASSQLK[136.11].E "sp|Q9GZT3|SLIRP_HUMAN,tr|H0YJW7|H0YJW7_HUMAN,tr|A0A087WUN7|A0A087WUN7_HUMAN,tr|G3V2S9|G3V2S9_HUMAN,tr|H0YJU7|H0YJU7_HUMAN,tr|H0YJ07|H0YJ07_HUMAN,tr|H0YJ40|H0YJ40_HUMAN,tr|G3V4X6|G3V4X6_HUMAN" 8 1374.7739 1.22 65953 14143 3 1374.774196 459.2652 "SRA stem-loop-interacting RNA-binding protein, mitochondrial OS=Homo sapiens OX=9606 GN=SLIRP PE=1 SV=1" 11 2595.6 - 819940 - - - 0.2488 - 2.368 0.501 - 314.7 1 2 0 0.0003 12 0 0 0 1.58E+07 1.30E+07 - - - 6.515 1 221125_WJC_METTL3_EV_vs_WT_F05.14145.14145.2 0.00092 14/24 K.GQLC[160.03]ELSC[160.03]STDYR.M "sp|Q99873|ANM1_HUMAN,tr|E9PKG1|E9PKG1_HUMAN" 2 1587.6657 2.44 65955 14145 2 1587.666734 794.8401 Protein arginine N-methyltransferase 1 OS=Homo sapiens OX=9606 GN=PRMT1 PE=1 SV=3 4.37 2595.9 - 406257 - - - 0.6248 - 2.959 0.62 - 759.1 1 2 0 0.001 13 0 0 0 3.83E+07 1.57E+07 - - - 6.4043 0.9998 221125_WJC_METTL3_EV_vs_WT_F05.14147.14147.3 0.00143 Sep-44 K.AQYEQTLAELHR[166.11].Y "sp|Q9UKS6|PACN3_HUMAN,tr|A0A0C4DGG1|A0A0C4DGG1_HUMAN,tr|E9PIY1|E9PIY1_HUMAN" 3 1467.7346 0.67 65957 14147 3 1467.734283 490.2521 Protein kinase C and casein kinase substrate in neurons protein 3 OS=Homo sapiens OX=9606 GN=PACSIN3 PE=1 SV=2 5.4 2596.2 - 305600 - - - -0.1901 - 1.932 0.363 - 85.8 1 2 0 -0.0003 12 0 0 0 2.28E+06 3.42E+06 - - - 4.4124 0.9984 221125_WJC_METTL3_EV_vs_WT_F05.14148.14148.2 0.00119 20-Nov K.QQQLLNEENLR.K "sp|Q5T9A4|ATD3B_HUMAN,sp|Q9NVI7|ATD3A_HUMAN,tr|H0Y2W2|H0Y2W2_HUMAN" 3 1383.7106 1.29 65958 14148 2 1383.715724 692.8626 ATPase family AAA domain-containing protein 3B OS=Homo sapiens OX=9606 GN=ATAD3B PE=1 SV=1 4.53 2596.3 - 289070 - - - 3.6727 - 1.908 0.437 - 454.8 1 2 0 0.0051 11 0 0 0 2.87E+06 2.22E+06 - - - 4.0148 0.9987 221125_WJC_METTL3_EV_vs_WT_F05.14149.14149.2 0.00103 20-Oct K.QQQLLNEENLR[166.11].K "sp|Q5T9A4|ATD3B_HUMAN,sp|Q9NVI7|ATD3A_HUMAN,tr|H0Y2W2|H0Y2W2_HUMAN" 3 1393.7189 1.29 65959 14149 2 1393.715428 697.8667 ATPase family AAA domain-containing protein 3B OS=Homo sapiens OX=9606 GN=ATAD3B PE=1 SV=1 4.53 2596.4 - 226240 - - - -2.4998 - 1.879 0.329 - 389.6 1 2 0 -0.0035 11 0 0 0 2.87E+06 2.22E+06 - - - 3.1762 0.9985 221125_WJC_METTL3_EV_vs_WT_F05.14154.14154.3 0.00204 Nov-44 R.IKTDYTLSIANR.L sp|Q96P63|SPB12_HUMAN 1 1393.7565 10.58 65962 14154 3 1393.758396 465.5928 Serpin B12 OS=Homo sapiens OX=9606 GN=SERPINB12 PE=1 SV=1 8.59 2597 - 948063 - - - 1.3395 - 2.08 0.34 - 180.6 1 2 1 0.0019 12 0 0 0 4.00E+07 3.78E+06 - - - 4.3602 0.9633 221125_WJC_METTL3_EV_vs_WT_F05.14156.14156.2 0.0316 12-Aug R.K[136.11]IELFGR[166.11].P sp|Q86U44|MTA70_HUMAN 1 879.5297 0 65964 14156 2 879.529586 440.7721 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 8.75 2597.2 - 813137 - - - -0.1387 - 1.827 0.248 - 307.3 1 1 0 -0.0001 7 0 0 0 5.45E+04 7.08E+07 - - - 2.7823 0.9999 221125_WJC_METTL3_EV_vs_WT_F05.14160.14160.3 0.00297 13/48 R.TVPSTPTLVVPHR.T sp|P12270|TPR_HUMAN 1 1402.7932 0.67 65968 14160 3 1402.793223 468.605 Nucleoprotein TPR OS=Homo sapiens OX=9606 GN=TPR PE=1 SV=3 9.44 2597.7 - 374249 - - - -0.0185 - 2.625 0.38 - 178.4 1 2 0 0 13 0 0 0 6.91E+06 1.02E+07 - - - 5.3932 0.9432 221125_WJC_METTL3_EV_vs_WT_F05.14162.14162.3 0.287 Jul-44 R.LSK[136.11]EELIQNMDR[166.11].V "sp|Q9Y618|NCOR2_HUMAN,tr|C9JQE8|C9JQE8_HUMAN,tr|C9JE98|C9JE98_HUMAN,tr|H0YGK8|H0YGK8_HUMAN,tr|C9J330|C9J330_HUMAN,tr|H7C1Y3|H7C1Y3_HUMAN,tr|C9J0Q5|C9J0Q5_HUMAN" 7 1492.7674 0.43 65970 14162 3 1492.766942 498.5964 Nuclear receptor corepressor 2 OS=Homo sapiens OX=9606 GN=NCOR2 PE=1 SV=3 4.68 2597.9 - 330662 - - - -0.339 - 1.589 0.164 - 43.2 1 2 1 -0.0005 12 0 0 0 3.50E+06 8.21E+06 - - - 1.652 0.9999 221125_WJC_METTL3_EV_vs_WT_F05.14163.14163.2 0.000114 24-Oct R.ELAEDGYSGVEVR.V "sp|P23396|RS3_HUMAN,tr|H0YEU2|H0YEU2_HUMAN,tr|E9PL09|E9PL09_HUMAN,tr|E9PK82|E9PK82_HUMAN,tr|F2Z2S8|F2Z2S8_HUMAN,tr|H0YCJ7|H0YCJ7_HUMAN,tr|E9PQ96|E9PQ96_HUMAN,tr|E9PJH4|E9PJH4_HUMAN,tr|E9PPU1|E9PPU1_HUMAN,tr|H0YF32|H0YF32_HUMAN" 10 1422.6627 10.52 65971 14163 2 1422.662875 712.3386 40S ribosomal protein S3 OS=Homo sapiens OX=9606 GN=RPS3 PE=1 SV=2 4 2598.1 - 318564 - - - 0.1314 - 2.046 0.516 - 243.1 1 2 0 0.0002 13 0 0 0 2.73E+06 2.59E+05 - - - 4.6895 0.9999 221125_WJC_METTL3_EV_vs_WT_F05.14168.14168.2 9.51E-07 28-Sep K.SAWQATTQQAGLDC[160.03]R[166.11].V "sp|Q86UK7|ZN598_HUMAN,tr|H3BQQ2|H3BQQ2_HUMAN,tr|H3BPG6|H3BPG6_HUMAN" 3 1701.7768 0.72 65975 14168 2 1701.778844 851.8957 E3 ubiquitin-protein ligase ZNF598 OS=Homo sapiens OX=9606 GN=ZNF598 PE=1 SV=1 5.55 2598.7 - 99356.5 - - - 1.1788 - 2.212 0.589 - 190.4 1 2 0 0.002 15 0 0 0 6.09E+05 8.47E+05 - - - 5.3426 1 221125_WJC_METTL3_EV_vs_WT_F05.14170.14170.2 0.000545 14/24 K.GQLC[160.03]ELSC[160.03]STDYR[166.11].M "sp|Q99873|ANM1_HUMAN,tr|E9PKG1|E9PKG1_HUMAN" 2 1597.674 3.17 65977 14170 2 1597.673629 799.8443 Protein arginine N-methyltransferase 1 OS=Homo sapiens OX=9606 GN=PRMT1 PE=1 SV=3 4.37 2598.8 - 1.20E+06 - - - -0.2397 - 2.988 0.614 - 726.1 1 2 0 -0.0004 13 0 0 0 4.99E+07 1.57E+07 - - - 6.3852 0.9999 221125_WJC_METTL3_EV_vs_WT_F05.14171.14171.3 3.69E-05 13/60 R.GITINAAHVEYSTAAR[166.11].H sp|P49411|EFTU_HUMAN 1 1682.8616 1.57 65978 14171 3 1682.860637 561.9611 "Elongation factor Tu, mitochondrial OS=Homo sapiens OX=9606 GN=TUFM PE=1 SV=2" 6.75 2598.9 - 616998 - - - -0.5443 - 2.321 0.41 - 180.7 1 2 0 -0.0009 16 0 0 0 1.39E+08 8.82E+07 - - - 5.2713 1 221125_WJC_METTL3_EV_vs_WT_F05.14172.14172.3 3.98E-07 15/40 K.NFEDVAFDEKK.N "sp|P07237|PDIA1_HUMAN,tr|A0A7P0TA97|A0A7P0TA97_HUMAN,tr|A0A7P0T8C0|A0A7P0T8C0_HUMAN,tr|H7BZ94|H7BZ94_HUMAN,tr|B3KTQ9|B3KTQ9_HUMAN,tr|A0A7P0TA71|A0A7P0TA71_HUMAN,tr|I3L4M2|I3L4M2_HUMAN,tr|A0A7P0T9D6|A0A7P0T9D6_HUMAN,tr|A0A7P0T9K9|A0A7P0T9K9_HUMAN,tr|H0Y3Z3|H0Y3Z3_HUMAN,tr|A0A7P0TA35|A0A7P0TA35_HUMAN,tr|A0A7P0TB26|A0A7P0TB26_HUMAN,tr|A0A7P0T9U6|A0A7P0T9U6_HUMAN,tr|I3L0S0|I3L0S0_HUMAN,tr|I3L3P5|I3L3P5_HUMAN,tr|A0A7P0T8J3|A0A7P0T8J3_HUMAN,tr|A0A7P0T8X1|A0A7P0T8X1_HUMAN" 17 1340.6248 0.92 65979 14172 3 1340.624338 447.8822 Protein disulfide-isomerase OS=Homo sapiens OX=9606 GN=P4HB PE=1 SV=3 4.32 2599.1 - 592619 - - - -0.3789 - 2.59 0.597 - 270.5 1 2 0 -0.0005 11 0 0 0 3.03E+07 3.30E+07 - - - 7.8993 0.9997 221125_WJC_METTL3_EV_vs_WT_F05.14173.14173.3 0.000123 13/48 R.LSTK[136.11]DPLPTIASR[166.11].E "sp|Q9BZE1|RM37_HUMAN,tr|S4R369|S4R369_HUMAN,tr|H0Y4J2|H0Y4J2_HUMAN,tr|A6NHR2|A6NHR2_HUMAN" 4 1415.8103 1.13 65980 14173 3 1415.812517 472.944 "39S ribosomal protein L37, mitochondrial OS=Homo sapiens OX=9606 GN=MRPL37 PE=1 SV=2" 8.75 2599.2 - 537052 - - - 1.5666 - 2.565 0.439 - 269.2 1 2 1 0.0022 13 0 0 0 1.04E+07 9.23E+06 - - - 5.9877 1 221125_WJC_METTL3_EV_vs_WT_F05.14177.14177.2 2.68E-10 14/30 K.EILGTAQSVGC[160.03]NVDGR.H sp|P30050|RL12_HUMAN 1 1674.7995 2.3 65984 14177 2 1674.800876 838.407 60S ribosomal protein L12 OS=Homo sapiens OX=9606 GN=RPL12 PE=1 SV=1 4.37 2599.7 - 290427 - - - 0.8019 - 2.758 0.697 - 501.3 1 2 0 0.0013 16 0 0 0 3.20E+06 1.39E+06 - - - 6.6828 0.9999 221125_WJC_METTL3_EV_vs_WT_F05.14178.14178.2 1.39E-07 13/32 R.TAGPLESSETEEASQLK.E "sp|Q9P2E9|RRBP1_HUMAN,tr|A0A087WU26|A0A087WU26_HUMAN,tr|A0A087WVV2|A0A087WVV2_HUMAN,tr|F8W7S5|F8W7S5_HUMAN" 4 1775.8425 2.26 65985 14178 2 1775.843251 888.9285 Ribosome-binding protein 1 OS=Homo sapiens OX=9606 GN=RRBP1 PE=1 SV=5 4.09 2599.8 - 246863 - - - 0.4212 - 2.467 0.593 - 282.3 1 2 0 0.0007 17 0 0 0 3.27E+07 1.45E+07 - - - 5.6407 1 221125_WJC_METTL3_EV_vs_WT_F05.14179.14179.2 2.41E-12 28-Dec R.GMATC[160.03]FAYGQTGSGK[136.11].T "sp|O00139|KIF2A_HUMAN,sp|Q8N4N8|KIF2B_HUMAN,tr|D6R9M0|D6R9M0_HUMAN,tr|A0A6Q8PFA6|A0A6Q8PFA6_HUMAN,tr|A0A6Q8PGG1|A0A6Q8PGG1_HUMAN,tr|A0A6Q8PGH7|A0A6Q8PGH7_HUMAN,tr|A0A6Q8PG37|A0A6Q8PG37_HUMAN,tr|A0A6Q8PH57|A0A6Q8PH57_HUMAN" 8 1542.6686 0.97 65986 14179 2 1542.666781 772.3416 Kinesin-like protein KIF2A OS=Homo sapiens OX=9606 GN=KIF2A PE=1 SV=3 8.2 2600 - 188863 - - - -1.2109 - 2.805 0.74 - 531.1 1 2 0 -0.0019 15 0 0 0 1.60E+06 1.64E+06 - - - 7.0418 1 221125_WJC_METTL3_EV_vs_WT_F05.14188.14188.2 1.09E-09 15/24 K.TDPTTLTDEEINR[166.11].F "sp|P11586|C1TC_HUMAN,tr|F5H2F4|F5H2F4_HUMAN,tr|V9GZ78|V9GZ78_HUMAN,tr|V9GYY3|V9GYY3_HUMAN,tr|A0A494C1T2|A0A494C1T2_HUMAN" 5 1513.7136 1.8 65993 14188 2 1513.712506 757.8641 "C-1-tetrahydrofolate synthase, cytoplasmic OS=Homo sapiens OX=9606 GN=MTHFD1 PE=1 SV=4" 3.92 2601 - 544836 - - - -0.691 - 2.736 0.645 - 920.4 1 2 0 -0.001 13 0 0 0 4.89E+07 2.72E+07 - - - 6.3878 1 221125_WJC_METTL3_EV_vs_WT_F05.14190.14190.3 1.08E-07 Dec-44 R.GHQLLSADVDIK.E "sp|P46459|NSF_HUMAN,tr|I3L0N3|I3L0N3_HUMAN" 2 1294.6881 0.52 65995 14190 3 1294.68869 432.57 Vesicle-fusing ATPase OS=Homo sapiens OX=9606 GN=NSF PE=1 SV=3 5.21 2601.2 - 466645 - - - 0.4441 - 2.461 0.517 - 264.2 1 2 0 0.0006 12 0 0 0 3.58E+06 6.87E+06 - - - 6.8001 1 221125_WJC_METTL3_EV_vs_WT_F05.14191.14191.3 2.69E-05 Dec-36 K.LGLSVFTHHR[166.11].V sp|Q9BU76|MMTA2_HUMAN 1 1175.6439 1.03 65996 14191 3 1175.644644 392.8886 Multiple myeloma tumor-associated protein 2 OS=Homo sapiens OX=9606 GN=MMTAG2 PE=1 SV=1 9.76 2601.4 - 439043 - - - 0.6362 - 2.752 0.436 - 163.4 1 2 0 0.0007 10 0 0 0 2.82E+06 2.73E+06 - - - 6.3572 1 221125_WJC_METTL3_EV_vs_WT_F05.14196.14196.2 2.31E-06 30-Nov K.EILGTAQSVGC[160.03]NVDGR[166.11].H sp|P30050|RL12_HUMAN 1 1684.8078 2.3 66001 14196 2 1684.80702 843.4112 60S ribosomal protein L12 OS=Homo sapiens OX=9606 GN=RPL12 PE=1 SV=1 4.37 2602 - 307394 - - - -0.4647 - 2.447 0.623 - 334.1 1 2 0 -0.0008 16 0 0 0 3.20E+06 1.39E+06 - - - 5.8423 1 221125_WJC_METTL3_EV_vs_WT_F05.14198.14198.2 2.31E-13 15/26 K.NQDEESQEAPELLK.R "sp|Q8NE71|ABCF1_HUMAN,tr|Q5STZ8|Q5STZ8_HUMAN,tr|H0YGW7|H0YGW7_HUMAN" 3 1628.753 1.5 66003 14198 2 1628.756368 815.3838 ATP-binding cassette sub-family F member 1 OS=Homo sapiens OX=9606 GN=ABCF1 PE=1 SV=2 3.91 2602.3 - 280196 - - - 2.0924 - 3.046 0.62 - 860.5 1 2 0 0.0034 14 0 0 0 3.18E+06 2.11E+06 - - - 6.4143 0.9998 221125_WJC_METTL3_EV_vs_WT_F05.14199.14199.3 0.000187 Nov-60 R.SESAPTLHPYSPLSPK.G "sp|Q8WUF5|IASPP_HUMAN,tr|K7EN03|K7EN03_HUMAN" 2 1709.8625 2.57 66004 14199 3 1709.863926 570.9614 RelA-associated inhibitor OS=Homo sapiens OX=9606 GN=PPP1R13L PE=1 SV=4 6.47 2602.4 - 265948 - - - 0.8626 - 2.255 0.36 - 112.2 1 2 0 0.0015 16 0 0 0 1.18E+08 4.59E+07 - - - 4.6397 1 221125_WJC_METTL3_EV_vs_WT_F05.14200.14200.2 2.53E-09 26-Nov K.NQDEESQEAPELLK[136.11].R "sp|Q8NE71|ABCF1_HUMAN,tr|Q5STZ8|Q5STZ8_HUMAN,tr|H0YGW7|H0YGW7_HUMAN" 3 1636.7672 1.5 66005 14200 2 1636.772224 819.3909 ATP-binding cassette sub-family F member 1 OS=Homo sapiens OX=9606 GN=ABCF1 PE=1 SV=2 3.91 2602.5 - 200624 - - - 3.0939 - 2.528 0.645 - 386.1 1 2 0 0.0051 14 0 0 0 3.18E+06 2.11E+06 - - - 6.1307 0.989 221125_WJC_METTL3_EV_vs_WT_F05.14201.14201.2 0.25 20-May R.ANHFFTVTDPR.N "sp|Q9H9B4|SFXN1_HUMAN,tr|D6RFI0|D6RFI0_HUMAN,tr|D6RDG7|D6RDG7_HUMAN,tr|S4R2X2|S4R2X2_HUMAN,tr|D6RAE9|D6RAE9_HUMAN" 5 1303.6309 0.66 66006 14201 2 1303.62747 652.8227 Sideroflexin-1 OS=Homo sapiens OX=9606 GN=SFXN1 PE=1 SV=4 6.79 2602.7 - 171386 - - - -2.658 - 1.118 0.283 - 64.7 1 2 0 -0.0035 11 0 0 0 1.44E+06 2.17E+06 - - - 1.4319 0.9998 221125_WJC_METTL3_EV_vs_WT_F05.14205.14205.3 0.000878 Dec-40 K.IRLENEIQTYR.S "sp|P13645|K1C10_HUMAN,tr|A0A1B0GVI3|A0A1B0GVI3_HUMAN" 2 1433.7627 442.42 66009 14205 3 1433.762281 478.9282 "Keratin, type I cytoskeletal 10 OS=Homo sapiens OX=9606 GN=KRT10 PE=1 SV=6" 6.14 2603 - 3.66E+07 - - - -0.2762 - 2.434 0.457 - 297.4 1 2 1 -0.0004 11 0 0 0 3.01E+09 6.79E+06 - - - 6.162 1 221125_WJC_METTL3_EV_vs_WT_F05.14206.14206.2 0.000135 16/20 K.IRLENEIQTYR.S "sp|P13645|K1C10_HUMAN,tr|A0A1B0GVI3|A0A1B0GVI3_HUMAN" 2 1433.7627 999 66010 14206 2 1433.763681 717.8886 "Keratin, type I cytoskeletal 10 OS=Homo sapiens OX=9606 GN=KRT10 PE=1 SV=6" 6.14 2603 - 4.05E+06 - - - 0.7003 - 3.21 0.522 - 355.2 1 2 1 0.001 11 0 0 0 7.23E+08 0.00E+00 - - - 6.0512 0.9993 221125_WJC_METTL3_EV_vs_WT_F05.14207.14207.3 0.00916 Sep-40 R.ANHFFTVTDPR.N "sp|Q9H9B4|SFXN1_HUMAN,tr|D6RFI0|D6RFI0_HUMAN,tr|D6RDG7|D6RDG7_HUMAN,tr|S4R2X2|S4R2X2_HUMAN,tr|D6RAE9|D6RAE9_HUMAN" 5 1303.6309 0.99 66011 14207 3 1303.631274 435.5509 Sideroflexin-1 OS=Homo sapiens OX=9606 GN=SFXN1 PE=1 SV=4 6.79 2603.1 - 1.77E+06 - - - 0.26 - 1.703 0.317 - 95 1 2 0 0.0003 11 0 0 0 3.09E+07 3.11E+07 - - - 3.5866 1 221125_WJC_METTL3_EV_vs_WT_F05.14208.14208.3 2.71E-08 15/52 K.K[136.11]ILDSVGIEADDDR[166.11].L sp|P05387|RLA2_HUMAN 1 1562.7907 1.58 66012 14208 3 1562.791201 521.9375 60S acidic ribosomal protein P2 OS=Homo sapiens OX=9606 GN=RPLP2 PE=1 SV=1 4.04 2603.2 - 917163 - - - 0.3295 - 2.651 0.5 - 382.1 1 2 0 0.0005 14 0 0 0 2.67E+07 1.68E+07 - - - 6.7053 1 221125_WJC_METTL3_EV_vs_WT_F05.14209.14209.3 7.89E-05 13/48 K.GQLC[160.03]ELSC[160.03]STDYR.M "sp|Q99873|ANM1_HUMAN,tr|E9PKG1|E9PKG1_HUMAN" 2 1587.6657 2.73 66013 14209 3 1587.665199 530.2292 Protein arginine N-methyltransferase 1 OS=Homo sapiens OX=9606 GN=PRMT1 PE=1 SV=3 4.37 2603.3 - 621008 - - - -0.342 - 1.97 0.515 - 232.5 1 2 0 -0.0005 13 0 0 0 2.93E+06 1.07E+06 - - - 6.1199 0.99 221125_WJC_METTL3_EV_vs_WT_F05.14210.14210.2 5.03E-05 24-Dec K.IELFGR[166.11]PHNVQPN.W sp|Q86U44|MTA70_HUMAN 1 1529.7978 -1 66014 14210 2 1529.799691 765.9062 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 6.75 2603.5 - 589444 - - - 1.2158 - 2.276 0.515 - 320 1 1 0 0.0019 13 0 0 0 0.00E+00 0.00E+00 - - - 4.955 1 221125_WJC_METTL3_EV_vs_WT_F05.14211.14211.3 8.54E-05 13/48 K.NNTVGLIQLNRPK.A sp|P30084|ECHM_HUMAN 1 1465.8365 1.7 66015 14211 3 1465.835927 489.6194 "Enoyl-CoA hydratase, mitochondrial OS=Homo sapiens OX=9606 GN=ECHS1 PE=1 SV=4" 11 2603.6 - 502489 - - - -0.3984 - 2.688 0.425 - 347.3 1 2 0 -0.0006 13 0 0 0 2.00E+07 1.17E+07 - - - 5.9591 0.9997 221125_WJC_METTL3_EV_vs_WT_F05.14212.14212.3 0.101 14/48 R.SWHDVQVSSAYVK.T "sp|O43399|TPD54_HUMAN,tr|A0A087WYR3|A0A087WYR3_HUMAN" 2 1504.731 2.97 66016 14212 3 1504.732483 502.5843 Tumor protein D54 OS=Homo sapiens OX=9606 GN=TPD52L2 PE=1 SV=2 6.46 2603.7 - 408706 - - - 0.957 - 2.085 0.335 - 186.9 1 2 0 0.0014 13 0 0 0 1.91E+07 6.41E+06 - - - 4.2667 0.9997 221125_WJC_METTL3_EV_vs_WT_F05.14214.14214.2 6.98E-07 15/30 K.ALSC[160.03]PGQPSNC[160.03]VTIPR.S "sp|Q15797|SMAD1_HUMAN,tr|D6RD62|D6RD62_HUMAN,tr|D6REQ3|D6REQ3_HUMAN,tr|D6RAY1|D6RAY1_HUMAN,tr|D6RDN7|D6RDN7_HUMAN" 5 1755.8396 1.89 66018 14214 2 1755.836787 878.9271 Mothers against decapentaplegic homolog 1 OS=Homo sapiens OX=9606 GN=SMAD1 PE=1 SV=1 8.11 2604 - 339615 - - - -1.6158 - 2.612 0.382 - 456.9 1 2 0 -0.0028 16 0 0 0 6.15E+06 3.25E+06 - - - 4.2221 0.9997 221125_WJC_METTL3_EV_vs_WT_F05.14216.14216.2 8.28E-08 13/30 K.ALSC[160.03]PGQPSNC[160.03]VTIPR[166.11].S "sp|Q15797|SMAD1_HUMAN,tr|D6RD62|D6RD62_HUMAN,tr|D6REQ3|D6REQ3_HUMAN,tr|D6RAY1|D6RAY1_HUMAN,tr|D6RDN7|D6RDN7_HUMAN" 5 1765.8479 1.89 66020 14216 2 1765.843839 883.9312 Mothers against decapentaplegic homolog 1 OS=Homo sapiens OX=9606 GN=SMAD1 PE=1 SV=1 8.11 2604.2 - 287800 - - - -2.2963 - 2.281 0.58 - 405.1 1 2 0 -0.0041 16 0 0 0 6.15E+06 3.25E+06 - - - 5.351 0.9996 221125_WJC_METTL3_EV_vs_WT_F05.14218.14218.3 0.00277 Dec-68 R.VLVASSVVAGESQK[136.11]PELK[136.11].A sp|Q06787|FMR1_HUMAN 1 1856.059 2.33 66022 14218 3 1856.05966 619.6936 Synaptic functional regulator FMR1 OS=Homo sapiens OX=9606 GN=FMR1 PE=1 SV=1 6.11 2604.5 - 220020 - - - 0.3669 - 2.043 0.338 - 114.7 1 2 0 0.0007 18 0 0 0 3.56E+06 1.53E+06 - - - 4.0872 0.9971 221125_WJC_METTL3_EV_vs_WT_F05.14221.14221.3 0.0225 Sep-44 R.QTGIVLNRPVLR.G "sp|Q13435|SF3B2_HUMAN,tr|E9PPJ0|E9PPJ0_HUMAN,tr|H0YCG1|H0YCG1_HUMAN,tr|E9PJ04|E9PJ04_HUMAN,tr|E9PJT3|E9PJT3_HUMAN" 5 1364.8252 1.15 66025 14221 3 1364.823886 455.949 Splicing factor 3B subunit 2 OS=Homo sapiens OX=9606 GN=SF3B2 PE=1 SV=2 12 2604.9 - 168944 - - - -0.9759 - 1.801 0.217 - 137.4 1 2 0 -0.0013 12 0 0 0 1.64E+06 1.42E+06 - - - 2.5898 0.9998 221125_WJC_METTL3_EV_vs_WT_F05.14229.14229.3 0.000108 16/56 R.INLPAPNPDHVGGYK.L sp|Q9UJS0|CMC2_HUMAN 1 1590.8154 1.05 66031 14229 3 1590.816242 531.2791 Calcium-binding mitochondrial carrier protein Aralar2 OS=Homo sapiens OX=9606 GN=SLC25A13 PE=1 SV=2 6.74 2605.8 - 655644 - - - 0.5035 - 2.475 0.342 - 293.1 1 2 0 0.0008 15 0 0 0 7.02E+06 6.70E+06 - - - 4.7175 0.9997 221125_WJC_METTL3_EV_vs_WT_F05.14232.14232.3 4.09E-06 14/52 K.VNPDLQVEVK[136.11]PSIR[166.11].A sp|Q96KR1|ZFR_HUMAN 1 1610.9111 2.4 66034 14232 3 1610.903558 537.9776 Zinc finger RNA-binding protein OS=Homo sapiens OX=9606 GN=ZFR PE=1 SV=2 6.04 2606.2 - 433550 - - - -4.6669 - 2.746 0.504 - 323.1 1 2 0 -0.0075 14 0 0 0 2.86E+07 1.19E+07 - - - 6.8415 1 221125_WJC_METTL3_EV_vs_WT_F05.14235.14235.2 1.64E-10 26-Oct K.K[136.11]ILDSVGIEADDDR[166.11].L sp|P05387|RLA2_HUMAN 1 1562.7907 -1 66037 14235 2 1562.787576 782.4026 60S acidic ribosomal protein P2 OS=Homo sapiens OX=9606 GN=RPLP2 PE=1 SV=1 4.04 2606.6 - 216146 - - - -1.99 - 2.638 0.66 - 245.7 1 2 0 -0.0031 14 0 0 0 0.00E+00 0.00E+00 - - - 6.349 0.9994 221125_WJC_METTL3_EV_vs_WT_F05.14238.14238.3 0.000105 Nov-48 R.GLQTVHINENFAK[136.11].L "sp|Q13573|SNW1_HUMAN,tr|G3V4X8|G3V4X8_HUMAN,tr|G3V3A4|G3V3A4_HUMAN" 3 1477.7769 1.21 66038 14238 3 1477.773283 493.5996 SNW domain-containing protein 1 OS=Homo sapiens OX=9606 GN=SNW1 PE=1 SV=1 6.75 2606.9 - 3.29E+06 - - - -2.432 - 2.015 0.361 - 107.9 1 2 0 -0.0036 13 0 0 0 1.54E+08 1.27E+08 - - - 4.4634 1 221125_WJC_METTL3_EV_vs_WT_F05.14241.14241.2 1.09E-05 17/22 V.PELATDPELEK[136.11]K[136.11].L "sp|Q86U44|MTA70_HUMAN,tr|B4E349|B4E349_HUMAN,tr|F5H6D8|F5H6D8_HUMAN,tr|H0YFV6|H0YFV6_HUMAN,tr|B4DTN4|B4DTN4_HUMAN" 5 1384.7421 0.01 66041 14241 2 1384.73846 693.3783 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 4.41 2607.2 - 1.76E+06 - - - -2.6005 - 3.344 0.566 - 949.3 1 1 0 -0.0036 12 0 0 0 4.18E+05 4.02E+07 - - - 6.3966 0.9994 221125_WJC_METTL3_EV_vs_WT_F05.14244.14244.3 4.35E-05 14/52 K.VNPDLQVEVKPSIR.A sp|Q96KR1|ZFR_HUMAN 1 1592.8886 2.4 66044 14244 3 1592.88249 531.9701 Zinc finger RNA-binding protein OS=Homo sapiens OX=9606 GN=ZFR PE=1 SV=2 6.04 2607.6 - 963843 - - - -3.8396 - 2.481 0.386 - 156.4 1 2 0 -0.0061 14 0 0 0 2.86E+07 1.19E+07 - - - 5.2566 1 221125_WJC_METTL3_EV_vs_WT_F05.14245.14245.2 3.02E-05 16/28 R.LAC[160.03]LSEEGNEIESGK.L "sp|Q9Y2L1|RRP44_HUMAN,tr|F2Z2C0|F2Z2C0_HUMAN,tr|G3V1J5|G3V1J5_HUMAN" 3 1634.7458 2.96 66045 14245 2 1634.738919 818.3802 Exosome complex exonuclease RRP44 OS=Homo sapiens OX=9606 GN=DIS3 PE=1 SV=2 4.09 2607.7 - 809024 - - - -4.1884 - 2.944 0.598 - 972.4 1 2 0 -0.0068 15 0 0 0 4.29E+07 1.45E+07 - - - 6.1103 0.9993 221125_WJC_METTL3_EV_vs_WT_F05.14246.14246.3 8.66E-06 Nov-56 R.ETGVDLTKDNMALQR.V "sp|P38646|GRP75_HUMAN,tr|H0Y8K0|H0Y8K0_HUMAN,tr|A0A7I2V2G2|A0A7I2V2G2_HUMAN,tr|A0A7I2V3F7|A0A7I2V3F7_HUMAN,tr|A0A7I2YQB2|A0A7I2YQB2_HUMAN,tr|D6RCD7|D6RCD7_HUMAN" 6 1689.8356 0.1 66046 14246 3 1689.838756 564.2858 "Stress-70 protein, mitochondrial OS=Homo sapiens OX=9606 GN=HSPA9 PE=1 SV=2" 4.56 2607.8 - 609703 - - - 1.8771 - 2.53 0.4 - 106.9 1 2 1 0.0032 15 0 0 0 1.21E+07 1.17E+08 - - - 5.4208 0.9999 221125_WJC_METTL3_EV_vs_WT_F05.14248.14248.3 7.10E-06 14/68 R.VLVASSVVAGESQKPELK.A sp|Q06787|FMR1_HUMAN 1 1840.0306 2.33 66048 14248 3 1840.027879 614.3508 Synaptic functional regulator FMR1 OS=Homo sapiens OX=9606 GN=FMR1 PE=1 SV=1 6.11 2608.1 - 458549 - - - -1.4674 - 2.524 0.423 - 156.6 1 2 0 -0.0027 18 0 0 0 3.56E+06 1.53E+06 - - - 5.5607 0.9993 221125_WJC_METTL3_EV_vs_WT_F05.14253.14253.3 3.46E-06 15/40 K.TRLEQEIATYR.R "sp|Q04695|K1C17_HUMAN,sp|P02533|K1C14_HUMAN,sp|P35900|K1C20_HUMAN,sp|P08779|K1C16_HUMAN,sp|P19012|K1C15_HUMAN,sp|P13646|K1C13_HUMAN,tr|A0A3B3IS58|A0A3B3IS58_HUMAN,tr|F5GWP8|F5GWP8_HUMAN,tr|K7ERE3|K7ERE3_HUMAN,tr|A8MT21|A8MT21_HUMAN" 10 1378.7205 561.91 66051 14253 3 1378.717256 460.5808 "Keratin, type I cytoskeletal 17 OS=Homo sapiens OX=9606 GN=KRT17 PE=1 SV=2" 5.81 2608.6 - 6.83E+06 - - - -2.3369 - 3.036 0.352 - 459.5 1 2 1 -0.0032 11 0 0 0 8.62E+09 1.53E+07 - - - 5.6184 0.9988 221125_WJC_METTL3_EV_vs_WT_F05.14254.14254.3 0.0185 Sep-48 R.GLQTVHINENFAK.L "sp|Q13573|SNW1_HUMAN,tr|G3V4X8|G3V4X8_HUMAN,tr|G3V3A4|G3V3A4_HUMAN" 3 1469.7627 1.21 66052 14254 3 1469.75948 490.9282 SNW domain-containing protein 1 OS=Homo sapiens OX=9606 GN=SNW1 PE=1 SV=1 6.75 2608.7 - 5.54E+06 - - - -2.1752 - 1.817 0.317 - 68.2 1 2 0 -0.0032 13 0 0 0 1.54E+08 1.27E+08 - - - 3.6925 1 221125_WJC_METTL3_EV_vs_WT_F05.14255.14255.2 0.0041 18/20 K.TRLEQEIATYR.R "sp|Q04695|K1C17_HUMAN,sp|P02533|K1C14_HUMAN,sp|P35900|K1C20_HUMAN,sp|P08779|K1C16_HUMAN,sp|P19012|K1C15_HUMAN,sp|P13646|K1C13_HUMAN,tr|A0A3B3IS58|A0A3B3IS58_HUMAN,tr|F5GWP8|F5GWP8_HUMAN,tr|K7ERE3|K7ERE3_HUMAN,tr|A8MT21|A8MT21_HUMAN" 10 1378.7205 999 66053 14255 2 1378.720041 690.3675 "Keratin, type I cytoskeletal 17 OS=Homo sapiens OX=9606 GN=KRT17 PE=1 SV=2" 5.81 2608.8 - 2.97E+06 - - - -0.317 - 3.309 0.558 - 499.4 1 2 1 -0.0004 11 0 0 0 5.89E+09 0.00E+00 - - - 6.3995 0.9997 221125_WJC_METTL3_EV_vs_WT_F05.14256.14256.3 2.38E-05 Dec-48 R.SSHYDELLAAEAR.A "sp|Q7KZF4|SND1_HUMAN,tr|H7C597|H7C597_HUMAN" 2 1460.6896 0.81 66054 14256 3 1460.684008 487.9038 Staphylococcal nuclease domain-containing protein 1 OS=Homo sapiens OX=9606 GN=SND1 PE=1 SV=1 4.65 2608.9 - 2.25E+06 - - - -3.8092 - 2.342 0.464 - 257.2 1 2 0 -0.0056 13 0 0 0 2.87E+07 3.53E+07 - - - 6.0189 1 221125_WJC_METTL3_EV_vs_WT_F05.14260.14260.3 5.29E-10 17/68 K.LMC[160.03]SLC[160.03]HC[160.03]PGATIGC[160.03]DVK[136.11].T "sp|Q8IWS0|PHF6_HUMAN,tr|Q5JRC6|Q5JRC6_HUMAN,tr|A0A0D9SGE8|A0A0D9SGE8_HUMAN" 3 2085.9018 0.74 66058 14260 3 2085.901041 696.3079 PHD finger protein 6 OS=Homo sapiens OX=9606 GN=PHF6 PE=1 SV=1 6.71 2609.4 - 1.30E+06 - - - -0.3538 - 2.788 0.674 - 264.5 1 2 0 -0.0007 18 0 0 0 1.61E+07 2.18E+07 - - - 8.6074 1 221125_WJC_METTL3_EV_vs_WT_F05.14263.14263.3 1.18E-10 16/56 A.SAVPELATDPELEK[136.11]K[136.11].L "sp|Q86U44|MTA70_HUMAN,tr|B4E349|B4E349_HUMAN,tr|F5H6D8|F5H6D8_HUMAN,tr|H0YFV6|H0YFV6_HUMAN,tr|B4DTN4|B4DTN4_HUMAN" 5 1641.8796 0 66059 14263 3 1641.87343 548.3005 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 4.41 2609.8 - 5.07E+07 - - - -3.7689 - 2.954 0.649 - 313.7 1 1 0 -0.0062 15 0 0 0 4.78E+06 1.24E+09 - - - 8.6004 0.9998 221125_WJC_METTL3_EV_vs_WT_F05.14266.14266.3 1.89E-06 16/64 K.SLYVAEYHSEPVEDEKP.- sp|P26196|DDX6_HUMAN 1 1990.916 1.16 66062 14266 3 1990.909676 664.6459 Probable ATP-dependent RNA helicase DDX6 OS=Homo sapiens OX=9606 GN=DDX6 PE=1 SV=2 4.25 2610 - 2.57E+06 - - - -3.1779 - 2.282 0.466 - 129.1 1 2 0 -0.0063 17 0 0 0 5.85E+08 5.02E+08 - - - 5.818 0.9998 221125_WJC_METTL3_EV_vs_WT_F05.14276.14276.3 3.76E-07 13/48 R.KPVAGALDVSFNK.F "sp|Q99627|CSN8_HUMAN,tr|E9PGT6|E9PGT6_HUMAN,tr|H7C3S9|H7C3S9_HUMAN" 3 1344.7402 1.17 66068 14276 3 1344.734504 449.254 COP9 signalosome complex subunit 8 OS=Homo sapiens OX=9606 GN=COPS8 PE=1 SV=1 8.59 2611.2 - 933540 - - - -4.1993 - 2.75 0.508 - 344.1 1 2 0 -0.0056 13 0 0 0 2.48E+07 2.11E+07 - - - 6.9449 0.9772 221125_WJC_METTL3_EV_vs_WT_F05.14279.14279.2 6.26E-07 15/28 A.SAVPELATDPELEK[136.11]K[136.11].L "sp|Q86U44|MTA70_HUMAN,tr|B4E349|B4E349_HUMAN,tr|F5H6D8|F5H6D8_HUMAN,tr|H0YFV6|H0YFV6_HUMAN,tr|B4DTN4|B4DTN4_HUMAN" 5 1641.8796 0.001 66070 14279 2 1641.874912 821.9471 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 4.41 2611.6 - 4.24E+06 - - - -2.8662 - 2.476 0.548 - 657 1 1 0 -0.0047 15 0 0 0 0.00E+00 1.13E+08 - - - 5.3161 0.913 221125_WJC_METTL3_EV_vs_WT_F05.14280.14280.2 2.24E-06 18/32 S.QELALTQSVGGDSSADR[166.11].L "sp|Q86U44|MTA70_HUMAN,tr|H0YFV6|H0YFV6_HUMAN" 2 1742.831 0.001 66071 14280 2 1742.822685 872.4228 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 4.03 2611.7 - 911745 - - - -4.7945 - 3.3 0.454 - 1125.5 1 1 0 -0.0084 17 0 0 0 0.00E+00 1.27E+07 - - - 5.3269 0.972 221125_WJC_METTL3_EV_vs_WT_F05.14283.14283.2 4.89E-05 24-Dec K.IELFGRPHNVQPN.W sp|Q86U44|MTA70_HUMAN 1 1519.7896 0.01 66072 14283 2 1519.792206 760.9021 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 6.75 2612.1 - 1.62E+06 - - - 1.7404 - 1.965 0.414 - 307.9 1 1 0 0.0026 13 0 0 0 4.02E+07 3.29E+09 - - - 3.8316 0.9804 221125_WJC_METTL3_EV_vs_WT_F05.14287.14287.3 0.0431 17/60 R.SESAPTLHPYSPLSPK[136.11].G "sp|Q8WUF5|IASPP_HUMAN,tr|K7EN03|K7EN03_HUMAN" 2 1717.8767 2.58 66074 14287 3 1717.880915 573.6328 RelA-associated inhibitor OS=Homo sapiens OX=9606 GN=PPP1R13L PE=1 SV=4 6.47 2612.6 - 1.77E+06 - - - 2.4821 - 1.999 0.15 - 202.9 1 2 0 0.0043 16 0 0 0 1.18E+08 4.59E+07 - - - 1.9884 1 221125_WJC_METTL3_EV_vs_WT_F05.14300.14300.2 1.69E-12 23/32 K.SLYVAEYHSEPVEDEKP.- sp|P26196|DDX6_HUMAN 1 1990.916 1.11 66082 14300 2 1990.914337 996.4653 Probable ATP-dependent RNA helicase DDX6 OS=Homo sapiens OX=9606 GN=DDX6 PE=1 SV=2 4.25 2614 - 1.74E+06 - - - -0.8368 - 3.889 0.756 - 1089.7 1 2 0 -0.0017 17 0 0 0 4.21E+07 3.80E+07 - - - 7.9634 0.9999 221125_WJC_METTL3_EV_vs_WT_F05.14306.14306.3 3.51E-10 20/64 K.VPEPC[160.03]PSIVTPAPAQQK.T sp|P22528|SPR1B_HUMAN 1 1817.9346 334.56 66085 14306 3 1817.927529 606.9855 Cornifin-B OS=Homo sapiens OX=9606 GN=SPRR1B PE=1 SV=2 5.97 2614.8 - 773663 - - - -3.8731 - 3.614 0.554 - 456 1 2 0 -0.007 17 0 0 0 1.02E+08 3.04E+05 - - - 7.9604 1 221125_WJC_METTL3_EV_vs_WT_F05.14309.14309.2 1.31E-12 26/32 K.SLYVAEYHSEPVEDEK[136.11]P.- sp|P26196|DDX6_HUMAN 1 1998.9302 1.1 66087 14309 2 1998.928545 1000.4724 Probable ATP-dependent RNA helicase DDX6 OS=Homo sapiens OX=9606 GN=DDX6 PE=1 SV=2 4.25 2615.2 - 1.67E+06 - - - -0.8294 - 4.344 0.748 - 2267.1 1 2 0 -0.0017 17 0 0 0 4.21E+07 3.82E+07 - - - 8.1763 1 221125_WJC_METTL3_EV_vs_WT_F05.14319.14319.2 2.62E-13 21/32 K.VPEPC[160.03]PSIVTPAPAQQK.T sp|P22528|SPR1B_HUMAN 1 1817.9346 999 66093 14319 2 1817.927769 909.9746 Cornifin-B OS=Homo sapiens OX=9606 GN=SPRR1B PE=1 SV=2 5.97 2616.3 - 1.67E+06 - - - -3.7411 - 4.031 0.667 - 1424.1 1 2 0 -0.0068 17 0 0 0 5.97E+07 0.00E+00 - - - 7.3926 1 221125_WJC_METTL3_EV_vs_WT_F05.14324.14324.3 4.62E-11 19/64 K.LSSWDQAETPGHTPSLR[166.11].W sp|O75533|SF3B1_HUMAN 1 1890.91 1.57 66096 14324 3 1890.906365 631.3106 Splicing factor 3B subunit 1 OS=Homo sapiens OX=9606 GN=SF3B1 PE=1 SV=3 5.32 2616.9 - 2.00E+06 - - - -1.9012 - 3.397 0.598 - 395.1 1 2 0 -0.0036 17 0 0 0 3.95E+07 2.53E+07 - - - 8.2955 1 221125_WJC_METTL3_EV_vs_WT_F05.14327.14327.3 1.85E-07 14/64 R.GLIPAGTQHSMIATTGK.M "sp|Q9Y520|PRC2C_HUMAN,tr|E7EPN9|E7EPN9_HUMAN,tr|A0A2R8Y424|A0A2R8Y424_HUMAN,tr|H7C5N8|H7C5N8_HUMAN,tr|A0A2R8Y7F4|A0A2R8Y7F4_HUMAN,tr|A0A2R8YET2|A0A2R8YET2_HUMAN" 6 1681.8821 1.93 66097 14327 3 1681.878661 561.6347 Protein PRRC2C OS=Homo sapiens OX=9606 GN=PRRC2C PE=1 SV=4 8.76 2617.3 - 1.24E+06 - - - -2.0685 - 2.917 0.493 - 254.4 1 2 0 -0.0035 17 0 0 0 3.87E+07 2.00E+07 - - - 6.74 0.9998 221125_WJC_METTL3_EV_vs_WT_F05.14330.14330.3 0.000356 13/32 K.K[136.11]DLTEYLSR[166.11].F "sp|O14979|HNRDL_HUMAN,tr|A0A087WUK2|A0A087WUK2_HUMAN" 2 1141.6098 0.001 66099 14330 3 1141.607195 381.5439 Heterogeneous nuclear ribonucleoprotein D-like OS=Homo sapiens OX=9606 GN=HNRNPDL PE=1 SV=3 6.07 2617.6 - 723729 - - - -2.2897 - 2.371 0.361 - 285.6 1 2 0 -0.0026 9 0 0 0 0.00E+00 2.23E+07 - - - 5.1659 0.9982 221125_WJC_METTL3_EV_vs_WT_F05.14333.14333.2 0.00883 22-Oct R.TWNDPSVQQDIK.F "sp|P11021|BIP_HUMAN,tr|A0A7P0TB36|A0A7P0TB36_HUMAN,tr|A0A7P0TAI0|A0A7P0TAI0_HUMAN" 3 1429.6838 0.53 66102 14333 2 1429.680238 715.8492 Endoplasmic reticulum chaperone BiP OS=Homo sapiens OX=9606 GN=HSPA5 PE=1 SV=2 4.21 2618 - 1.15E+06 - - - -2.4621 - 1.511 0.365 - 157.9 1 2 0 -0.0035 12 0 0 0 5.59E+07 1.06E+08 - - - 2.8219 0.9995 221125_WJC_METTL3_EV_vs_WT_F05.14335.14335.3 0.00097 Sep-56 R.VAFDPEQK[136.11]PLHGVLK[136.11].T sp|Q14684|RRP1B_HUMAN 1 1692.9534 1.55 66104 14335 3 1692.948485 565.3251 Ribosomal RNA processing protein 1 homolog B OS=Homo sapiens OX=9606 GN=RRP1B PE=1 SV=3 6.72 2618.2 - 728406 - - - -2.8985 - 2.209 0.387 - 96.3 1 2 0 -0.0049 15 0 0 0 1.58E+07 1.02E+07 - - - 4.9213 0.9999 221125_WJC_METTL3_EV_vs_WT_F05.14341.14341.3 2.34E-07 14/52 K.AIVIC[160.03]PTDEDLKDR.T "sp|Q9BUJ2|HNRL1_HUMAN,tr|A0A0A0MRA5|A0A0A0MRA5_HUMAN,tr|M0R3F1|M0R3F1_HUMAN,tr|B7Z4B8|B7Z4B8_HUMAN" 4 1643.8189 1.05 66108 14341 3 1643.817218 548.9469 Heterogeneous nuclear ribonucleoprotein U-like protein 1 OS=Homo sapiens OX=9606 GN=HNRNPUL1 PE=1 SV=2 4.23 2618.7 - 5.48E+06 - - - -1.0062 - 3.102 0.516 - 272.2 1 2 1 -0.0017 14 0 0 0 1.04E+08 9.87E+07 - - - 7.3009 1 221125_WJC_METTL3_EV_vs_WT_F05.14345.14345.3 0.000114 13/64 R.GLIPAGTQHSMIATTGK[136.11].M "sp|Q9Y520|PRC2C_HUMAN,tr|E7EPN9|E7EPN9_HUMAN,tr|A0A2R8Y424|A0A2R8Y424_HUMAN,tr|H7C5N8|H7C5N8_HUMAN,tr|A0A2R8Y7F4|A0A2R8Y7F4_HUMAN,tr|A0A2R8YET2|A0A2R8YET2_HUMAN" 6 1689.8963 1.76 66112 14345 3 1689.894853 564.3061 Protein PRRC2C OS=Homo sapiens OX=9606 GN=PRRC2C PE=1 SV=4 8.76 2619.2 - 750362 - - - -0.8799 - 2.918 0.461 - 224 1 2 0 -0.0015 17 0 0 0 3.87E+07 2.19E+07 - - - 6.3847 1 221125_WJC_METTL3_EV_vs_WT_F05.14351.14351.3 2.79E-06 14/48 R.SASPYHGFTIVNR.L "sp|Q9NPI6|DCP1A_HUMAN,tr|A0A087WT55|A0A087WT55_HUMAN,tr|A0A087WXD0|A0A087WXD0_HUMAN,tr|A0A087WVE6|A0A087WVE6_HUMAN" 4 1447.7208 1.96 66116 14351 3 1447.719384 483.5809 mRNA-decapping enzyme 1A OS=Homo sapiens OX=9606 GN=DCP1A PE=1 SV=3 8.49 2620 - 866932 - - - -0.9864 - 2.913 0.561 - 284.9 1 2 0 -0.0014 13 0 0 0 8.74E+07 4.46E+07 - - - 7.6931 1 221125_WJC_METTL3_EV_vs_WT_F05.14352.14352.3 1.02E-06 15/60 R.SFAGAVSPQEEEEFR[166.11]R[166.11].L "sp|P33992|MCM5_HUMAN,tr|B1AHB1|B1AHB1_HUMAN" 2 1857.876 0.52 66117 14352 3 1857.873291 620.2993 DNA replication licensing factor MCM5 OS=Homo sapiens OX=9606 GN=MCM5 PE=1 SV=5 4.49 2620.1 - 693079 - - - -1.4748 - 2.354 0.507 - 182.5 1 2 0 -0.0027 16 0 0 0 5.32E+07 1.02E+08 - - - 6.3885 0.9999 221125_WJC_METTL3_EV_vs_WT_F05.14360.14360.3 5.03E-06 14/48 R.SASPYHGFTIVNR[166.11].L "sp|Q9NPI6|DCP1A_HUMAN,tr|A0A087WT55|A0A087WT55_HUMAN,tr|A0A087WXD0|A0A087WXD0_HUMAN,tr|A0A087WVE6|A0A087WVE6_HUMAN" 4 1457.7291 2.09 66123 14360 3 1457.725088 486.917 mRNA-decapping enzyme 1A OS=Homo sapiens OX=9606 GN=DCP1A PE=1 SV=3 8.49 2621.1 - 832456 - - - -2.7399 - 2.7 0.531 - 161.9 1 2 0 -0.004 13 0 0 0 8.68E+07 4.15E+07 - - - 7.152 1 221125_WJC_METTL3_EV_vs_WT_F05.14366.14366.3 3.90E-07 24/68 K.LGEMWNNTAADDK[136.11]QPYEK[136.11].K "sp|P09429|HMGB1_HUMAN,tr|Q5T7C4|Q5T7C4_HUMAN" 2 2124.9757 0.13 66127 14366 3 2124.971615 709.3325 High mobility group protein B1 OS=Homo sapiens OX=9606 GN=HMGB1 PE=1 SV=3 4.32 2621.8 - 1.59E+06 - - - -1.9318 - 3.927 0.645 - 615.4 1 2 1 -0.0041 18 0 0 0 9.72E+06 7.33E+07 - - - 9.1361 0.9931 221125_WJC_METTL3_EV_vs_WT_F05.14367.14367.2 9.27E-08 20-Nov K.HTDESLGDC[160.03]SF.L "sp|Q86U44|MTA70_HUMAN,tr|H0YFV6|H0YFV6_HUMAN" 2 1266.4823 - 66128 14367 2 1266.481115 634.2484 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 4.02 2621.9 - 1.21E+06 - - - -0.9207 - 2.567 0.493 - 515.3 1 1 0 -0.0012 11 0 0 0 - - - - - 5.2323 1 221125_WJC_METTL3_EV_vs_WT_F05.14368.14368.2 4.25E-06 19/26 K.SQIHDIVLVGGSTR[166.11].L "sp|P11142|HSP7C_HUMAN,tr|E9PNE6|E9PNE6_HUMAN,tr|A8K7Q2|A8K7Q2_HUMAN,tr|E9PKE3|E9PKE3_HUMAN,tr|E9PN89|E9PN89_HUMAN" 5 1490.8081 0.15 66129 14368 2 1490.808813 746.4113 Heat shock cognate 71 kDa protein OS=Homo sapiens OX=9606 GN=HSPA8 PE=1 SV=1 6.46 2622.1 - 1.21E+06 - - - 0.5044 - 3.365 0.599 - 1433.9 1 2 0 0.0008 14 0 0 0 2.76E+08 1.85E+09 - - - 6.51 1 221125_WJC_METTL3_EV_vs_WT_F05.14369.14369.2 1.76E-11 19/36 R.LLEGEDAHLSSQQASGQSY.S sp|P08779|K1C16_HUMAN 1 2018.9181 - 66130 14369 2 2018.914824 1010.4663 "Keratin, type I cytoskeletal 16 OS=Homo sapiens OX=9606 GN=KRT16 PE=1 SV=4" 4.13 2622.2 - 915810 - - - -1.6365 - 3.645 0.721 - 906 1 1 0 -0.0033 19 0 0 0 - - - - - 7.545 0.9999 221125_WJC_METTL3_EV_vs_WT_F05.14374.14374.4 0.000788 17/84 R.VAFDPEQK[136.11]PLHGVLK[136.11].T sp|Q14684|RRP1B_HUMAN 1 1692.9534 1.39 66133 14374 4 1692.950466 424.2456 Ribosomal RNA processing protein 1 homolog B OS=Homo sapiens OX=9606 GN=RRP1B PE=1 SV=3 6.72 2622.8 - 828701 - - - -1.7283 - 3.092 0.469 - 142.3 1 2 0 -0.0029 15 0 0 0 4.31E+07 3.09E+07 - - - 3.7113 0.9998 221125_WJC_METTL3_EV_vs_WT_F05.14375.14375.2 1.71E-07 26-Nov K.NGSEADIDEGLYSR[166.11].Q "sp|P22314|UBA1_HUMAN,tr|Q5JRS3|Q5JRS3_HUMAN,tr|Q5JRS2|Q5JRS2_HUMAN,tr|Q5JRS0|Q5JRS0_HUMAN,tr|Q5JRS1|Q5JRS1_HUMAN,tr|Q5JRR9|Q5JRR9_HUMAN" 6 1534.6775 0.13 66134 14375 2 1534.680291 768.346 Ubiquitin-like modifier-activating enzyme 1 OS=Homo sapiens OX=9606 GN=UBA1 PE=1 SV=3 3.92 2623 - 765197 - - - 1.8186 - 2.062 0.615 - 299.7 1 2 0 0.0028 14 0 0 0 6.25E+06 4.68E+07 - - - 5.3985 0.9998 221125_WJC_METTL3_EV_vs_WT_F05.14376.14376.3 1.18E-05 20/56 K.APSIDGKEELDLAEK.M "sp|Q9H0E9|BRD8_HUMAN,tr|B5MCW3|B5MCW3_HUMAN,tr|H7C179|H7C179_HUMAN,tr|H0YAH7|H0YAH7_HUMAN,tr|H7C128|H7C128_HUMAN,tr|H0YA84|H0YA84_HUMAN,tr|H7C127|H7C127_HUMAN" 7 1613.8148 1.21 66135 14376 3 1613.816814 538.9456 Bromodomain-containing protein 8 OS=Homo sapiens OX=9606 GN=BRD8 PE=1 SV=2 4.18 2623.1 - 474120 - - - 1.2281 - 2.864 0.447 - 369.5 1 2 1 0.002 15 0 0 0 9.84E+06 8.14E+06 - - - 6.2687 0.9355 221125_WJC_METTL3_EV_vs_WT_F05.14378.14378.3 0.00334 13/48 R.SR[166.11]PTSFADELAAR[166.11].L "sp|Q641Q2|WAC2A_HUMAN,sp|Q9Y4E1|WAC2C_HUMAN,tr|F8W7U3|F8W7U3_HUMAN,tr|J3KP36|J3KP36_HUMAN,tr|E7ESD2|E7ESD2_HUMAN,tr|A0A0A0MT65|A0A0A0MT65_HUMAN,tr|A0A0A0MR88|A0A0A0MR88_HUMAN,tr|A0A087WYF6|A0A087WYF6_HUMAN,tr|A0A096LPC5|A0A096LPC5_HUMAN" 9 1439.7272 1.95 66137 14378 3 1439.714661 480.9163 WASH complex subunit 2A OS=Homo sapiens OX=9606 GN=WASHC2A PE=1 SV=3 5.79 2623.4 - 393063 - - - -8.6968 - 2.434 0.255 - 187.6 1 2 0 -0.0125 13 0 0 0 3.48E+07 1.78E+07 - - - 3.7913 1 221125_WJC_METTL3_EV_vs_WT_F05.14382.14382.3 1.51E-09 15/56 R.DYDVDHPGEADSVLR.G "sp|Q8IX01|SUGP2_HUMAN,tr|M0R2Z9|M0R2Z9_HUMAN,tr|M0R3F6|M0R3F6_HUMAN" 3 1686.7485 1.43 66139 14382 3 1686.74764 563.2568 SURP and G-patch domain-containing protein 2 OS=Homo sapiens OX=9606 GN=SUGP2 PE=1 SV=2 4.03 2623.8 - 2.15E+06 - - - -0.5353 - 2.747 0.635 - 203.5 1 2 0 -0.0009 15 0 0 0 4.49E+07 3.15E+07 - - - 8.2562 1 221125_WJC_METTL3_EV_vs_WT_F05.14383.14383.3 4.41E-07 13/52 K.SQIHDIVLVGGSTR.L "sp|P11142|HSP7C_HUMAN,tr|E9PNE6|E9PNE6_HUMAN,tr|A8K7Q2|A8K7Q2_HUMAN,tr|E9PKE3|E9PKE3_HUMAN,tr|E9PN89|E9PN89_HUMAN" 5 1480.7998 0.15 66140 14383 3 1480.799699 494.6072 Heat shock cognate 71 kDa protein OS=Homo sapiens OX=9606 GN=HSPA8 PE=1 SV=1 6.46 2623.9 - 8.51E+06 - - - -0.0621 - 2.586 0.521 - 174 1 2 0 -0.0001 14 0 0 0 2.71E+09 1.81E+10 - - - 6.8736 1 221125_WJC_METTL3_EV_vs_WT_F05.14384.14384.3 2.55E-07 13/56 R.DYDVDHPGEADSVLR[166.11].G "sp|Q8IX01|SUGP2_HUMAN,tr|M0R2Z9|M0R2Z9_HUMAN,tr|M0R3F6|M0R3F6_HUMAN" 3 1696.7568 1.43 66141 14384 3 1696.755291 566.5929 SURP and G-patch domain-containing protein 2 OS=Homo sapiens OX=9606 GN=SUGP2 PE=1 SV=2 4.03 2623.9 - 1.68E+06 - - - -0.897 - 2.236 0.623 - 132.5 1 2 0 -0.0015 15 0 0 0 4.49E+07 3.15E+07 - - - 7.5851 0.9998 221125_WJC_METTL3_EV_vs_WT_F05.14385.14385.2 0.000217 14/26 K.SQIHDIVLVGGSTR.L "sp|P11142|HSP7C_HUMAN,tr|E9PNE6|E9PNE6_HUMAN,tr|A8K7Q2|A8K7Q2_HUMAN,tr|E9PKE3|E9PKE3_HUMAN,tr|E9PN89|E9PN89_HUMAN" 5 1480.7998 0.15 66142 14385 2 1480.796692 741.4072 Heat shock cognate 71 kDa protein OS=Homo sapiens OX=9606 GN=HSPA8 PE=1 SV=1 6.46 2624.1 - 677901 - - - -2.0928 - 2.597 0.55 - 697.4 1 2 0 -0.0031 14 0 0 0 2.76E+08 1.85E+09 - - - 5.4972 1 221125_WJC_METTL3_EV_vs_WT_F05.14387.14387.3 4.18E-09 17/68 K.LGEMWNNTAADDKQPYEK.K "sp|P09429|HMGB1_HUMAN,tr|Q5T7C4|Q5T7C4_HUMAN" 2 2108.9473 0.11 66144 14387 3 2108.944428 703.9897 High mobility group protein B1 OS=Homo sapiens OX=9606 GN=HMGB1 PE=1 SV=3 4.32 2624.3 - 541032 - - - -1.3713 - 3.323 0.696 - 311.1 1 2 1 -0.0029 18 0 0 0 9.72E+06 8.67E+07 - - - 9.2892 0.9995 221125_WJC_METTL3_EV_vs_WT_F05.14388.14388.2 2.90E-05 22-Dec R.AQVQEFC[160.03]DYGTK[136.11].E "sp|Q86U44|MTA70_HUMAN,tr|H0YFV6|H0YFV6_HUMAN" 2 1452.6435 0.001 66145 14388 2 1452.639252 727.329 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 4.37 2624.4 - 526433 - - - -2.9106 - 2.555 0.48 - 453.9 1 2 0 -0.0042 12 0 0 0 0.00E+00 2.46E+07 - - - 5.0531 0.999 221125_WJC_METTL3_EV_vs_WT_F05.14394.14394.3 0.0293 14/44 R.LNMHNLVEPVNK.D "sp|Q9NPI6|DCP1A_HUMAN,tr|A0A087WT55|A0A087WT55_HUMAN,tr|A0A087WXD0|A0A087WXD0_HUMAN,tr|A0A087WVE6|A0A087WVE6_HUMAN" 4 1406.734 14.68 66149 14394 3 1406.73303 469.9186 mRNA-decapping enzyme 1A OS=Homo sapiens OX=9606 GN=DCP1A PE=1 SV=3 6.75 2625.2 - 910134 - - - -0.7038 - 1.702 0.298 - 124.3 1 2 0 -0.001 12 0 0 0 9.72E+07 6.62E+06 - - - 3.3362 1 221125_WJC_METTL3_EV_vs_WT_F05.14397.14397.3 4.42E-06 13/56 R.IVLYGDSNC[160.03]LDDSHR.Q sp|Q14703|MBTP1_HUMAN 1 1762.7944 1.04 66152 14397 3 1762.795045 588.6054 Membrane-bound transcription factor site-1 protease OS=Homo sapiens OX=9606 GN=MBTPS1 PE=1 SV=1 4.41 2625.6 - 418651 - - - 0.3387 - 2.055 0.568 - 70.5 1 2 0 0.0006 15 0 0 0 5.99E+06 5.77E+06 - - - 6.7519 0.9368 221125_WJC_METTL3_EV_vs_WT_F05.14402.14402.3 0.242 Aug-32 R.R[166.11]C[160.03]EDIC[160.03]WIK[136.11].T "sp|Q9HCE5|MET14_HUMAN,tr|D6RBL4|D6RBL4_HUMAN" 2 1296.6074 0.03 66155 14402 3 1296.601547 433.2097 N6-adenosine-methyltransferase non-catalytic subunit OS=Homo sapiens OX=9606 GN=METTL14 PE=1 SV=2 6.06 2626.1 - 424877 - - - -4.501 - 1.597 0.195 - 115.1 1 2 0 -0.0058 9 0 0 0 8.39E+05 3.26E+07 - - - 2.1233 0.9999 221125_WJC_METTL3_EV_vs_WT_F05.14406.14406.3 6.37E-07 14/52 K.AHGGYSVFAGVGER.T "sp|P06576|ATPB_HUMAN,tr|F8W079|F8W079_HUMAN,tr|H0YI37|H0YI37_HUMAN,tr|F8W0P7|F8W0P7_HUMAN,tr|H0YH81|H0YH81_HUMAN" 5 1405.6739 1.7 66157 14406 3 1405.673021 469.5652 "ATP synthase subunit beta, mitochondrial OS=Homo sapiens OX=9606 GN=ATP5F1B PE=1 SV=3" 6.79 2626.6 - 2.47E+06 - - - -0.5983 - 2.14 0.456 - 155.8 1 2 0 -0.0008 14 0 0 0 5.11E+08 3.00E+08 - - - 5.6456 0.982 221125_WJC_METTL3_EV_vs_WT_F05.14413.14413.3 0.000174 Sep-72 R.LLEGEDAHLSSQQASGQSY.S sp|P08779|K1C16_HUMAN 1 2018.9181 - 66162 14413 3 2018.915074 673.98 "Keratin, type I cytoskeletal 16 OS=Homo sapiens OX=9606 GN=KRT16 PE=1 SV=4" 4.13 2627.4 - 6.18E+06 - - - -1.5127 - 2.048 0.415 - 52.4 1 1 0 -0.0031 19 0 0 0 - - - - - 4.9272 0.9483 221125_WJC_METTL3_EV_vs_WT_F05.14415.14415.2 0.125 16-Sep R.R[166.11]C[160.03]EDIC[160.03]WIK[136.11].T "sp|Q9HCE5|MET14_HUMAN,tr|D6RBL4|D6RBL4_HUMAN" 2 1296.6074 0.01 66164 14415 2 1296.598318 649.311 N6-adenosine-methyltransferase non-catalytic subunit OS=Homo sapiens OX=9606 GN=METTL14 PE=1 SV=2 6.06 2627.7 - 781088 - - - -6.9913 - 1.833 0.254 - 318.2 1 2 0 -0.0091 9 0 0 0 2.25E+05 3.39E+07 - - - 2.6673 1 221125_WJC_METTL3_EV_vs_WT_F05.14418.14418.3 0.000316 16/52 K.SQIHDIVLVGGSTR[166.11].L "sp|P11142|HSP7C_HUMAN,tr|E9PNE6|E9PNE6_HUMAN,tr|A8K7Q2|A8K7Q2_HUMAN,tr|E9PKE3|E9PKE3_HUMAN,tr|E9PN89|E9PN89_HUMAN" 5 1490.8081 0.15 66166 14418 3 1490.809036 497.9433 Heat shock cognate 71 kDa protein OS=Homo sapiens OX=9606 GN=HSPA8 PE=1 SV=1 6.46 2628 - 4.62E+08 - - - 0.654 - 2.992 0.487 - 291 1 2 0 0.001 14 0 0 0 2.71E+09 1.80E+10 - - - 6.8818 0.9999 221125_WJC_METTL3_EV_vs_WT_F05.14423.14423.4 0.00124 18/78 K.LR[166.11]EVVETPLLHPER[166.11].F "sp|P35998|PRS7_HUMAN,tr|C9JX88|C9JX88_HUMAN" 2 1706.9582 0.95 66168 14423 4 1706.955312 427.7468 26S proteasome regulatory subunit 7 OS=Homo sapiens OX=9606 GN=PSMC2 PE=1 SV=3 5.5 2628.6 - 445845 - - - -1.7177 - 3.76 0.532 - 436 1 2 1 -0.0029 14 0 0 0 2.07E+07 2.18E+07 - - - 4.3377 0.9713 221125_WJC_METTL3_EV_vs_WT_F05.14427.14427.2 2.68E-05 24-Sep K.DHTPSQELALTQS.V "sp|Q86U44|MTA70_HUMAN,tr|H0YFV6|H0YFV6_HUMAN" 2 1425.6736 - 66170 14427 2 1425.669975 713.8441 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 4.35 2629.1 - 5.15E+06 - - - -2.5335 - 1.982 0.495 - 263.3 1 1 0 -0.0036 13 0 0 0 - - - - - 4.4517 0.9866 221125_WJC_METTL3_EV_vs_WT_F05.14428.14428.2 3.22E-06 13/22 Q.IHDLVLVGGSTR[166.11].L "sp|P0DMV8|HS71A_HUMAN,sp|P34931|HS71L_HUMAN,sp|P11142|HSP7C_HUMAN,sp|P0DMV9|HS71B_HUMAN,tr|E9PNE6|E9PNE6_HUMAN,tr|A8K7Q2|A8K7Q2_HUMAN,tr|E9PKE3|E9PKE3_HUMAN,tr|E9PN89|E9PN89_HUMAN,tr|Q53FA3|Q53FA3_HUMAN,tr|V9GZ37|V9GZ37_HUMAN,tr|A0A0G2JIW1|A0A0G2JIW1_HUMAN" 11 1275.7175 0.001 66171 14428 2 1275.715347 638.866 Heat shock 70 kDa protein 1A OS=Homo sapiens OX=9606 GN=HSPA1A PE=1 SV=1 6.74 2629.2 - 364887 - - - -1.6524 - 2.501 0.44 - 765.5 1 1 0 -0.0021 12 0 0 0 0.00E+00 1.09E+07 - - - 4.7021 1 221125_WJC_METTL3_EV_vs_WT_F05.14433.14433.2 2.87E-08 15/26 K.AHGGYSVFAGVGER.T "sp|P06576|ATPB_HUMAN,tr|F8W079|F8W079_HUMAN,tr|H0YI37|H0YI37_HUMAN,tr|F8W0P7|F8W0P7_HUMAN,tr|H0YH81|H0YH81_HUMAN" 5 1405.6739 2.21 66174 14433 2 1405.674773 703.8442 "ATP synthase subunit beta, mitochondrial OS=Homo sapiens OX=9606 GN=ATP5F1B PE=1 SV=3" 6.79 2629.8 - 956142 - - - 0.6481 - 2.989 0.6 - 577.6 1 2 0 0.0009 14 0 0 0 5.20E+07 2.36E+07 - - - 6.22 1 221125_WJC_METTL3_EV_vs_WT_F05.14448.14448.2 4.45E-06 20-Dec R.EEAENTLQSFR.Q "sp|P08670|VIME_HUMAN,tr|B0YJC5|B0YJC5_HUMAN,tr|B0YJC4|B0YJC4_HUMAN" 3 1322.6103 1.86 66184 14448 2 1322.607173 662.3124 Vimentin OS=Homo sapiens OX=9606 GN=VIM PE=1 SV=4 4.25 2631.6 - 1.28E+06 - - - -2.3333 - 2.346 0.604 - 834.5 1 2 0 -0.0031 11 0 0 0 1.37E+08 7.38E+07 - - - 5.808 0.9999 221125_WJC_METTL3_EV_vs_WT_F05.14450.14450.3 0.006 14/52 R.SLEAQVAHADQQLR[166.11].D "sp|Q14980|NUMA1_HUMAN,tr|A0A087WY61|A0A087WY61_HUMAN,tr|H0YFY6|H0YFY6_HUMAN,tr|K4DIE0|K4DIE0_HUMAN" 4 1574.804 1.69 66186 14450 3 1574.804819 525.942 Nuclear mitotic apparatus protein 1 OS=Homo sapiens OX=9606 GN=NUMA1 PE=1 SV=2 5.3 2631.8 - 669860 - - - 0.4959 - 2.45 0.361 - 159.3 1 2 0 0.0008 14 0 0 0 2.39E+07 1.41E+07 - - - 4.946 0.9985 221125_WJC_METTL3_EV_vs_WT_F05.14451.14451.3 0.00017 Sep-60 R.LK[136.11]ESFLVTGSQDC[160.03]TVK[136.11].L "sp|Q12788|TBL3_HUMAN,tr|J3KNP2|J3KNP2_HUMAN,tr|A0A087WYP7|A0A087WYP7_HUMAN" 3 1826.9419 1.83 66187 14451 3 1826.938194 609.9879 Transducin beta-like protein 3 OS=Homo sapiens OX=9606 GN=TBL3 PE=1 SV=2 6.06 2631.9 - 527982 - - - -2.0291 - 1.693 0.428 - 80.9 1 2 1 -0.0037 16 0 0 0 1.63E+07 8.89E+06 - - - 4.6617 0.9998 221125_WJC_METTL3_EV_vs_WT_F05.14454.14454.3 0.000653 13/40 R.VVDLMAHMASK.E "sp|P04406|G3P_HUMAN,tr|E7EUT5|E7EUT5_HUMAN" 2 1200.5995 0.02 66188 14454 3 1200.601403 401.2071 Glyceraldehyde-3-phosphate dehydrogenase OS=Homo sapiens OX=9606 GN=GAPDH PE=1 SV=3 6.71 2632.3 - 544627 - - - 1.585 - 2.072 0.405 - 178.4 1 2 0 0.0019 11 0 0 0 1.14E+07 4.99E+08 - - - 5.1244 1 221125_WJC_METTL3_EV_vs_WT_F05.14456.14456.3 6.89E-09 18/60 K.IRPGEQEQYESTIGFK.L "sp|P11171|EPB41_HUMAN,tr|A0A2R8Y6D0|A0A2R8Y6D0_HUMAN,tr|A0A2R8YFR9|A0A2R8YFR9_HUMAN,tr|A0A2R8Y420|A0A2R8Y420_HUMAN,tr|A0A2R8YCW8|A0A2R8YCW8_HUMAN,tr|A0A2R8Y7N0|A0A2R8Y7N0_HUMAN,tr|A0A3B3ITP0|A0A3B3ITP0_HUMAN,tr|A0A3B3IU06|A0A3B3IU06_HUMAN,tr|A0A2R8Y5G2|A0A2R8Y5G2_HUMAN,tr|A0A1B0GWG0|A0A1B0GWG0_HUMAN,tr|A0A2U3TZH6|A0A2U3TZH6_HUMAN,tr|A0A3B3IUD6|A0A3B3IUD6_HUMAN,tr|A0A2R8Y7Y3|A0A2R8Y7Y3_HUMAN,tr|A0A2R8Y570|A0A2R8Y570_HUMAN,tr|A0A2R8Y6G5|A0A2R8Y6G5_HUMAN,tr|A0A2R8Y5Z6|A0A2R8Y5Z6_HUMAN,tr|A0A2R8YD30|A0A2R8YD30_HUMAN,tr|A0A2R8Y4N6|A0A2R8Y4N6_HUMAN" 18 1880.9268 0.73 66190 14456 3 1880.931318 627.9829 Protein 4.1 OS=Homo sapiens OX=9606 GN=EPB41 PE=1 SV=4 4.79 2632.6 - 611194 - - - 2.3797 - 3.1 0.586 - 504.8 1 2 0 0.0045 16 0 0 0 9.11E+06 1.24E+07 - - - 7.9751 0.9997 221125_WJC_METTL3_EV_vs_WT_F05.14461.14461.2 6.66E-05 20-Nov R.EEAENTLQSFR[166.11].Q "sp|P08670|VIME_HUMAN,tr|B0YJC5|B0YJC5_HUMAN,tr|B0YJC4|B0YJC4_HUMAN" 3 1332.6185 1.87 66192 14461 2 1332.616318 667.3165 Vimentin OS=Homo sapiens OX=9606 GN=VIM PE=1 SV=4 4.25 2633.3 - 2.11E+06 - - - -1.6591 - 2.177 0.427 - 622.4 1 2 0 -0.0022 11 0 0 0 1.37E+08 7.36E+07 - - - 4.2987 1 221125_WJC_METTL3_EV_vs_WT_F05.14463.14463.3 4.53E-06 14/60 K.IR[166.11]PGEQEQYESTIGFK[136.11].L "sp|P11171|EPB41_HUMAN,tr|A0A2R8Y6D0|A0A2R8Y6D0_HUMAN,tr|A0A2R8YFR9|A0A2R8YFR9_HUMAN,tr|A0A2R8Y420|A0A2R8Y420_HUMAN,tr|A0A2R8YCW8|A0A2R8YCW8_HUMAN,tr|A0A2R8Y7N0|A0A2R8Y7N0_HUMAN,tr|A0A3B3ITP0|A0A3B3ITP0_HUMAN,tr|A0A3B3IU06|A0A3B3IU06_HUMAN,tr|A0A2R8Y5G2|A0A2R8Y5G2_HUMAN,tr|A0A1B0GWG0|A0A1B0GWG0_HUMAN,tr|A0A2U3TZH6|A0A2U3TZH6_HUMAN,tr|A0A3B3IUD6|A0A3B3IUD6_HUMAN,tr|A0A2R8Y7Y3|A0A2R8Y7Y3_HUMAN,tr|A0A2R8Y570|A0A2R8Y570_HUMAN,tr|A0A2R8Y6G5|A0A2R8Y6G5_HUMAN,tr|A0A2R8Y5Z6|A0A2R8Y5Z6_HUMAN,tr|A0A2R8YD30|A0A2R8YD30_HUMAN,tr|A0A2R8Y4N6|A0A2R8Y4N6_HUMAN" 18 1898.9493 0.75 66194 14463 3 1898.946147 633.9904 Protein 4.1 OS=Homo sapiens OX=9606 GN=EPB41 PE=1 SV=4 4.79 2633.5 - 559773 - - - -1.6667 - 2.489 0.534 - 265.9 1 2 0 -0.0032 16 0 0 0 9.42E+06 1.26E+07 - - - 6.8325 0.9997 221125_WJC_METTL3_EV_vs_WT_F05.14464.14464.3 1.22E-07 20/52 K.LR[166.11]EVVETPLLHPER[166.11].F "sp|P35998|PRS7_HUMAN,tr|C9JX88|C9JX88_HUMAN" 2 1706.9582 0.64 66195 14464 3 1706.951897 569.9934 26S proteasome regulatory subunit 7 OS=Homo sapiens OX=9606 GN=PSMC2 PE=1 SV=3 5.5 2633.6 - 452823 - - - -3.7183 - 3.393 0.58 - 550.3 1 2 1 -0.0063 14 0 0 0 8.63E+06 1.35E+07 - - - 8.2514 0.9992 221125_WJC_METTL3_EV_vs_WT_F05.14468.14468.3 0.000224 Dec-52 R.SLEAQVAHADQQLR.D "sp|Q14980|NUMA1_HUMAN,tr|A0A087WY61|A0A087WY61_HUMAN,tr|H0YFY6|H0YFY6_HUMAN,tr|K4DIE0|K4DIE0_HUMAN" 4 1564.7958 1.69 66197 14468 3 1564.7906 522.6059 Nuclear mitotic apparatus protein 1 OS=Homo sapiens OX=9606 GN=NUMA1 PE=1 SV=2 5.3 2634.2 - 767346 - - - -3.3027 - 2.489 0.337 - 128.1 1 2 0 -0.0052 14 0 0 0 2.39E+07 1.41E+07 - - - 4.7191 0.9999 221125_WJC_METTL3_EV_vs_WT_F05.14470.14470.3 0.00381 13/40 R.MVNHFIAEFKR.K "sp|P11142|HSP7C_HUMAN,tr|A8K7Q2|A8K7Q2_HUMAN,tr|E9PKE3|E9PKE3_HUMAN,tr|E9PN89|E9PN89_HUMAN" 4 1390.718 0.11 66199 14470 3 1390.716355 464.5799 Heat shock cognate 71 kDa protein OS=Homo sapiens OX=9606 GN=HSPA8 PE=1 SV=1 8.52 2634.4 - 401564 - - - -1.1656 - 2.126 0.381 - 233.6 1 2 0 -0.0016 11 0 0 0 1.19E+07 1.11E+08 - - - 4.93 1 221125_WJC_METTL3_EV_vs_WT_F05.14479.14479.2 1.23E-06 15/18 L.DELSRYPEDK.L "sp|P43243|MATR3_HUMAN,tr|A8MXP9|A8MXP9_HUMAN,tr|D6R991|D6R991_HUMAN,tr|A0A0R4J2E8|A0A0R4J2E8_HUMAN,tr|D6REM6|D6REM6_HUMAN" 5 1250.5779 1.31 66205 14479 2 1250.574822 626.2962 Matrin-3 OS=Homo sapiens OX=9606 GN=MATR3 PE=1 SV=2 4.32 2635.5 - 693554 - - - -2.4581 - 3.04 0.529 - 1273.6 1 1 1 -0.0031 10 0 0 0 1.47E+08 1.12E+08 - - - 6.0508 1 221125_WJC_METTL3_EV_vs_WT_F05.14483.14483.2 3.55E-08 18/22 R.DLDELSR[166.11]YPEDK[136.11].L "sp|P43243|MATR3_HUMAN,tr|A8MXP9|A8MXP9_HUMAN,tr|D6R991|D6R991_HUMAN,tr|A0A0R4J2E8|A0A0R4J2E8_HUMAN,tr|D6REM6|D6REM6_HUMAN" 5 1496.7114 1.39 66208 14483 2 1496.709215 749.363 Matrin-3 OS=Homo sapiens OX=9606 GN=MATR3 PE=1 SV=2 4.11 2636.1 - 2.09E+06 - - - -1.4418 - 3.332 0.656 - 1116.3 1 2 1 -0.0022 12 0 0 0 4.46E+08 3.21E+08 - - - 7.0523 0.9937 221125_WJC_METTL3_EV_vs_WT_F05.14487.14487.3 0.00344 Nov-44 R.DLDELSR[166.11]YPEDK[136.11].L "sp|P43243|MATR3_HUMAN,tr|A8MXP9|A8MXP9_HUMAN,tr|D6R991|D6R991_HUMAN,tr|A0A0R4J2E8|A0A0R4J2E8_HUMAN,tr|D6REM6|D6REM6_HUMAN" 5 1496.7114 1.39 66211 14487 3 1496.706327 499.9111 Matrin-3 OS=Homo sapiens OX=9606 GN=MATR3 PE=1 SV=2 4.11 2636.4 - 2.66E+07 - - - -3.3714 - 1.929 0.352 - 113.2 1 2 1 -0.005 12 0 0 0 3.17E+09 2.27E+09 - - - 4.2842 0.9998 221125_WJC_METTL3_EV_vs_WT_F05.14488.14488.3 0.00158 13/56 K.TVGAAQLKPTLNQLK.Q "sp|Q9Y3S1|WNK2_HUMAN,tr|H0Y7J9|H0Y7J9_HUMAN,tr|H0Y493|H0Y493_HUMAN,tr|F8W9F9|F8W9F9_HUMAN,tr|H0Y7R3|H0Y7R3_HUMAN,tr|H0Y7T5|H0Y7T5_HUMAN" 6 1580.925 1.43 66212 14488 3 1580.923805 527.9823 Serine\threonine-protein kinase WNK2 OS=Homo sapiens OX=9606 GN=WNK2 PE=1 SV=4 10 2636.6 - 1.16E+06 - - - -0.7508 - 2.037 0.378 - 100.3 1 2 0 -0.0012 15 0 0 0 1.40E+07 9.84E+06 - - - 4.6105 0.9998 221125_WJC_METTL3_EV_vs_WT_F05.14489.14489.4 3.37E-06 17/78 K.LREVVETPLLHPER.F "sp|P35998|PRS7_HUMAN,tr|C9JX88|C9JX88_HUMAN" 2 1686.9417 0.85 66213 14489 4 1686.938435 422.7427 26S proteasome regulatory subunit 7 OS=Homo sapiens OX=9606 GN=PSMC2 PE=1 SV=3 5.5 2636.7 - 666226 - - - -1.9378 - 3.247 0.484 - 371.7 1 2 1 -0.0033 14 0 0 0 1.82E+07 2.15E+07 - - - 3.8665 1 221125_WJC_METTL3_EV_vs_WT_F05.14493.14493.2 4.03E-10 15/30 K.WQPGEEPAGSVVQDSR.L "sp|Q9Y5K5|UCHL5_HUMAN,tr|Q5LJA9|Q5LJA9_HUMAN,tr|Q5LJB0|Q5LJB0_HUMAN,tr|Q5LJA5|Q5LJA5_HUMAN" 4 1740.8067 2.68 66217 14493 2 1740.804773 871.4106 Ubiquitin carboxyl-terminal hydrolase isozyme L5 OS=Homo sapiens OX=9606 GN=UCHL5 PE=1 SV=3 4.14 2637.2 - 443052 - - - -1.1225 - 2.624 0.691 - 596.7 1 2 0 -0.002 16 0 0 0 5.01E+07 1.87E+07 - - - 6.5159 0.9999 221125_WJC_METTL3_EV_vs_WT_F05.14494.14494.3 0.00283 13/52 K.LREVVETPLLHPER.F "sp|P35998|PRS7_HUMAN,tr|C9JX88|C9JX88_HUMAN" 2 1686.9417 0.64 66218 14494 3 1686.941797 563.3212 26S proteasome regulatory subunit 7 OS=Homo sapiens OX=9606 GN=PSMC2 PE=1 SV=3 5.5 2637.4 - 242641 - - - 0.0551 - 2.867 0.454 - 280.8 1 2 1 0.0001 14 0 0 0 8.63E+06 1.35E+07 - - - 6.4007 0.9994 221125_WJC_METTL3_EV_vs_WT_F05.14497.14497.3 0.00322 Dec-44 R.DLDELSRYPEDK.L "sp|P43243|MATR3_HUMAN,tr|A8MXP9|A8MXP9_HUMAN,tr|D6R991|D6R991_HUMAN,tr|A0A0R4J2E8|A0A0R4J2E8_HUMAN,tr|D6REM6|D6REM6_HUMAN" 5 1478.6889 1.4 66219 14497 3 1478.690413 493.9036 Matrin-3 OS=Homo sapiens OX=9606 GN=MATR3 PE=1 SV=2 4.11 2637.8 - 4.10E+07 - - - 1.0212 - 2.244 0.385 - 134.8 1 2 1 0.0015 12 0 0 0 3.19E+09 2.28E+09 - - - 5.0723 1 221125_WJC_METTL3_EV_vs_WT_F05.14498.14498.2 0.000463 15/22 R.DLDELSRYPEDK.L "sp|P43243|MATR3_HUMAN,tr|A8MXP9|A8MXP9_HUMAN,tr|D6R991|D6R991_HUMAN,tr|A0A0R4J2E8|A0A0R4J2E8_HUMAN,tr|D6REM6|D6REM6_HUMAN" 5 1478.6889 1.39 66220 14498 2 1478.687807 740.3517 Matrin-3 OS=Homo sapiens OX=9606 GN=MATR3 PE=1 SV=2 4.11 2637.8 - 4.22E+06 - - - -0.7412 - 3.077 0.577 - 758.8 1 2 1 -0.0011 12 0 0 0 4.47E+08 3.21E+08 - - - 6.2597 0.9997 221125_WJC_METTL3_EV_vs_WT_F05.14499.14499.3 0.000215 13/48 K.VKELVEFAQDDDR.L sp|Q14677|EPN4_HUMAN 1 1562.7577 1.58 66221 14499 3 1562.755087 521.9265 Clathrin interactor 1 OS=Homo sapiens OX=9606 GN=CLINT1 PE=1 SV=1 4.11 2637.9 - 1.10E+06 - - - -1.6407 - 2.511 0.444 - 233.3 1 2 1 -0.0026 13 0 0 0 3.12E+07 1.97E+07 - - - 5.9857 0.9983 221125_WJC_METTL3_EV_vs_WT_F05.14503.14503.3 0.000138 Aug-36 R.ERSDTFINLR.E sp|P17655|CAN2_HUMAN 1 1249.6415 1.14 66225 14503 3 1249.638621 417.5544 Calpain-2 catalytic subunit OS=Homo sapiens OX=9606 GN=CAPN2 PE=1 SV=6 6.17 2638.4 - 604616 - - - -2.3031 - 1.88 0.392 - 117.8 1 2 1 -0.0029 10 0 0 0 8.99E+06 7.87E+06 - - - 4.7532 1 221125_WJC_METTL3_EV_vs_WT_F05.14504.14504.2 1.08E-10 15/30 K.WQPGEEPAGSVVQDSR[166.11].L "sp|Q9Y5K5|UCHL5_HUMAN,tr|Q5LJA9|Q5LJA9_HUMAN,tr|Q5LJB0|Q5LJB0_HUMAN,tr|Q5LJA5|Q5LJA5_HUMAN" 4 1750.815 1.72 66226 14504 2 1750.811288 876.4148 Ubiquitin carboxyl-terminal hydrolase isozyme L5 OS=Homo sapiens OX=9606 GN=UCHL5 PE=1 SV=3 4.14 2638.6 - 494480 - - - -2.1184 - 2.673 0.634 - 569.3 1 2 0 -0.0037 16 0 0 0 1.09E+07 6.31E+06 - - - 6.1398 0.9935 221125_WJC_METTL3_EV_vs_WT_F05.14511.14511.3 0.0498 Sep-48 K.VK[136.11]ELVEFAQDDDR[166.11].L sp|Q14677|EPN4_HUMAN 1 1580.7801 1.56 66231 14511 3 1580.779981 527.934 Clathrin interactor 1 OS=Homo sapiens OX=9606 GN=CLINT1 PE=1 SV=1 4.11 2639.4 - 1.04E+06 - - - -0.0886 - 1.685 0.291 - 81.1 2 2 1 -0.0001 13 0 0 0 3.07E+07 1.97E+07 - - - 3.0597 0.994 221125_WJC_METTL3_EV_vs_WT_F05.14512.14512.3 0.0428 Jul-36 R.ER[166.11]SDTFINLR[166.11].E sp|P17655|CAN2_HUMAN 1 1269.658 1.16 66232 14512 3 1269.657966 424.2266 Calpain-2 catalytic subunit OS=Homo sapiens OX=9606 GN=CAPN2 PE=1 SV=6 6.17 2639.6 - 843493 - - - -0.0575 - 1.793 0.258 - 87.9 1 2 1 -0.0001 10 0 0 0 9.17E+06 7.87E+06 - - - 3.1216 0.9926 221125_WJC_METTL3_EV_vs_WT_F05.14514.14514.3 0.361 Sep-60 K.EILGTAQSVGC[160.03]NVDGR.H sp|P30050|RL12_HUMAN 1 1674.7995 1.39 66234 14514 3 1674.794564 559.2738 60S ribosomal protein L12 OS=Homo sapiens OX=9606 GN=RPL12 PE=1 SV=1 4.37 2639.8 - 283122 - - - -2.9669 - 1.742 0.256 - 103.4 1 2 0 -0.005 16 0 0 0 2.26E+08 1.63E+08 - - - 2.8169 0.9869 221125_WJC_METTL3_EV_vs_WT_F05.14515.14515.3 0.00101 Sep-32 V.NHFIAEFK[136.11]R[166.11].K "sp|P11142|HSP7C_HUMAN,tr|A8K7Q2|A8K7Q2_HUMAN,tr|E9PKE3|E9PKE3_HUMAN,tr|E9PN89|E9PN89_HUMAN" 4 1178.6315 0.45 66235 14515 3 1178.630951 393.8845 Heat shock cognate 71 kDa protein OS=Homo sapiens OX=9606 GN=HSPA8 PE=1 SV=1 8.75 2639.9 - 263819 - - - -0.5057 - 2.064 0.381 - 90 1 1 0 -0.0006 9 0 0 0 4.98E+05 1.10E+06 - - - 4.9715 1 221125_WJC_METTL3_EV_vs_WT_F05.14524.14524.2 3.55E-08 15/30 R.VANPSGNLTETYVQDR.G "sp|P21333|FLNA_HUMAN,tr|Q60FE5|Q60FE5_HUMAN" 2 1762.8486 1.22 66242 14524 2 1762.845859 882.4316 Filamin-A OS=Homo sapiens OX=9606 GN=FLNA PE=1 SV=4 4.37 2641.1 - 747015 - - - -1.5503 - 3.318 0.64 - 842.9 1 2 0 -0.0027 16 0 0 0 3.28E+07 2.70E+07 - - - 6.7159 1 221125_WJC_METTL3_EV_vs_WT_F05.14525.14525.3 7.85E-07 16/60 K.WQPGEEPAGSVVQDSR.L "sp|Q9Y5K5|UCHL5_HUMAN,tr|Q5LJA9|Q5LJA9_HUMAN,tr|Q5LJB0|Q5LJB0_HUMAN,tr|Q5LJA5|Q5LJA5_HUMAN" 4 1740.8067 1.28 66243 14525 3 1740.805088 581.2762 Ubiquitin carboxyl-terminal hydrolase isozyme L5 OS=Homo sapiens OX=9606 GN=UCHL5 PE=1 SV=3 4.14 2641.2 - 735926 - - - -0.9415 - 2.287 0.51 - 240.5 1 2 0 -0.0016 16 0 0 0 1.16E+07 9.01E+06 - - - 6.3481 1 221125_WJC_METTL3_EV_vs_WT_F05.14526.14526.2 1.76E-06 15/30 R.VANPSGNLTETYVQDR[166.11].G "sp|P21333|FLNA_HUMAN,tr|Q60FE5|Q60FE5_HUMAN" 2 1772.8569 1.22 66244 14526 2 1772.855925 887.4357 Filamin-A OS=Homo sapiens OX=9606 GN=FLNA PE=1 SV=4 4.37 2641.3 - 594531 - - - -0.5285 - 3.186 0.594 - 744.2 1 2 0 -0.0009 16 0 0 0 3.28E+07 2.70E+07 - - - 6.2769 0.9997 221125_WJC_METTL3_EV_vs_WT_F05.14530.14530.2 0.00169 20-Sep K.ETTIDGEELVK.L "sp|P52732|KIF11_HUMAN,tr|A0A7I2YQY4|A0A7I2YQY4_HUMAN,tr|A0A7I2V3A9|A0A7I2V3A9_HUMAN,tr|A0A7I2V3V3|A0A7I2V3V3_HUMAN" 4 1232.6136 3.54 66248 14530 2 1232.61302 617.3141 Kinesin-like protein KIF11 OS=Homo sapiens OX=9606 GN=KIF11 PE=1 SV=2 4 2641.9 - 277654 - - - -0.4811 - 2.004 0.362 - 233.1 1 2 0 -0.0006 11 0 0 0 5.30E+06 1.50E+06 - - - 3.5951 1 221125_WJC_METTL3_EV_vs_WT_F05.14534.14534.2 3.28E-07 15/30 R.ELNNSTNGIVIEPSEK.A "sp|Q14681|KCTD2_HUMAN,tr|J3QSC8|J3QSC8_HUMAN" 2 1742.8687 7 66250 14534 2 1742.873311 872.4416 BTB\POZ domain-containing protein KCTD2 OS=Homo sapiens OX=9606 GN=KCTD2 PE=1 SV=3 4.25 2642.4 - 5.44E+06 - - - 2.6692 - 2.965 0.575 - 406.7 1 2 0 0.0047 16 0 0 0 2.64E+08 3.77E+07 - - - 5.9586 1 221125_WJC_METTL3_EV_vs_WT_F05.14535.14535.2 2.18E-12 16/30 K.EILGTAQSVGC[160.03]NVDGR.H sp|P30050|RL12_HUMAN 1 1674.7995 1.37 66251 14535 2 1674.798699 838.407 60S ribosomal protein L12 OS=Homo sapiens OX=9606 GN=RPL12 PE=1 SV=1 4.37 2642.4 - 3.19E+06 - - - -0.498 - 3.179 0.684 - 993.7 1 2 0 -0.0008 16 0 0 0 2.42E+08 1.76E+08 - - - 6.9362 1 221125_WJC_METTL3_EV_vs_WT_F05.14536.14536.2 0.000109 18/30 K.EILGTAQSVGC[160.03]NVDGR[166.11].H sp|P30050|RL12_HUMAN 1 1684.8078 1.37 66252 14536 2 1684.804769 843.4112 60S ribosomal protein L12 OS=Homo sapiens OX=9606 GN=RPL12 PE=1 SV=1 4.37 2642.5 - 2.64E+06 - - - -1.8008 - 3.426 0.574 - 1174.6 1 2 0 -0.003 16 0 0 0 2.42E+08 1.76E+08 - - - 6.307 0.9655 221125_WJC_METTL3_EV_vs_WT_F05.14537.14537.3 0.0011 Oct-44 K.DHTPSQELALTQ.S "sp|Q86U44|MTA70_HUMAN,tr|H0YFV6|H0YFV6_HUMAN" 2 1338.6416 - 66253 14537 3 1338.638359 447.2211 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 4.35 2642.6 - 1.41E+06 - - - -2.3905 - 1.825 0.418 - 94.3 1 1 0 -0.0032 12 0 0 0 - - - - - 4.8669 0.8891 221125_WJC_METTL3_EV_vs_WT_F05.14540.14540.2 0.0168 16-Dec D.ELSRYPEDK.L "sp|P43243|MATR3_HUMAN,tr|A8MXP9|A8MXP9_HUMAN,tr|D6R991|D6R991_HUMAN,tr|A0A0R4J2E8|A0A0R4J2E8_HUMAN,tr|D6REM6|D6REM6_HUMAN" 5 1135.551 1.7 66256 14540 2 1135.550446 568.7828 Matrin-3 OS=Homo sapiens OX=9606 GN=MATR3 PE=1 SV=2 4.68 2643 - 708595 - - - -0.4465 - 2.402 0.357 - 687.8 1 1 1 -0.0005 9 0 0 0 1.69E+07 9.93E+06 - - - 4.2128 0.9998 221125_WJC_METTL3_EV_vs_WT_F05.14541.14541.3 0.0015 14/56 K.GFALVGVGSEASSK[136.11]K[136.11].L "sp|Q16630|CPSF6_HUMAN,tr|F8WJN3|F8WJN3_HUMAN" 2 1451.7955 1.74 66257 14541 3 1451.7955 484.9391 Cleavage and polyadenylation specificity factor subunit 6 OS=Homo sapiens OX=9606 GN=CPSF6 PE=1 SV=2 8.59 2643.1 - 496201 - - - 0.0041 - 2.263 0.362 - 131.8 1 2 0 0 15 0 0 0 7.83E+06 4.51E+06 - - - 4.707 0.9997 221125_WJC_METTL3_EV_vs_WT_F05.14542.14542.2 1.12E-05 26-Oct R.SFSTASAITPSVSR.T "sp|P13647|K2C5_HUMAN,tr|F8VV57|F8VV57_HUMAN,tr|F8VU69|F8VU69_HUMAN" 3 1409.7151 999 66258 14542 2 1409.711603 705.8648 "Keratin, type II cytoskeletal 5 OS=Homo sapiens OX=9606 GN=KRT5 PE=1 SV=3" 9.47 2643.2 - 408520 - - - -2.4508 - 2.31 0.546 - 349.3 1 2 0 -0.0035 14 0 0 0 2.53E+07 0.00E+00 - - - 5.1737 0.9999 221125_WJC_METTL3_EV_vs_WT_F05.14544.14544.3 6.16E-05 15/36 K.NQVLVFVHSR.K "sp|O75643|U520_HUMAN,tr|A0A494C1A5|A0A494C1A5_HUMAN" 2 1197.6618 1.9 66260 14544 3 1197.662091 400.2279 U5 small nuclear ribonucleoprotein 200 kDa helicase OS=Homo sapiens OX=9606 GN=SNRNP200 PE=1 SV=2 9.76 2643.5 - 263271 - - - 0.2087 - 2.673 0.374 - 413.2 1 2 0 0.0003 10 0 0 0 2.34E+06 1.23E+06 - - - 5.581 1 221125_WJC_METTL3_EV_vs_WT_F05.14548.14548.3 5.37E-07 14/60 K.EILGTAQSVGC[160.03]NVDGR[166.11].H sp|P30050|RL12_HUMAN 1 1684.8078 1.39 66262 14548 3 1684.806103 562.6099 60S ribosomal protein L12 OS=Homo sapiens OX=9606 GN=RPL12 PE=1 SV=1 4.37 2644 - 9.14E+06 - - - -1.009 - 2.361 0.572 - 237.8 1 2 0 -0.0017 16 0 0 0 2.27E+08 1.63E+08 - - - 7.1211 0.9994 221125_WJC_METTL3_EV_vs_WT_F05.14549.14549.3 0.00102 Sep-60 R.ELNNSTNGIVIEPSEK.A "sp|Q14681|KCTD2_HUMAN,tr|J3QSC8|J3QSC8_HUMAN" 2 1742.8687 4.85 66263 14549 3 1742.870497 581.9635 BTB\POZ domain-containing protein KCTD2 OS=Homo sapiens OX=9606 GN=KCTD2 PE=1 SV=3 4.25 2644.1 - 2.82E+06 - - - 1.0546 - 1.744 0.339 - 75.1 1 2 0 0.0018 16 0 0 0 7.02E+07 1.45E+07 - - - 3.7461 0.9994 221125_WJC_METTL3_EV_vs_WT_F05.14550.14550.3 0.0048 Sep-40 R.HNLSLNEC[160.03]FVK.V "sp|O43638|FOXS1_HUMAN,sp|Q12948|FOXC1_HUMAN,sp|Q99958|FOXC2_HUMAN" 3 1359.6605 2.37 66264 14550 3 1359.659249 454.2275 Forkhead box protein S1 OS=Homo sapiens OX=9606 GN=FOXS1 PE=2 SV=2 6.74 2644.1 - 1.56E+06 - - - -0.9355 - 1.954 0.291 - 147 1 2 0 -0.0013 11 0 0 0 2.88E+07 1.21E+07 - - - 3.687 0.9991 221125_WJC_METTL3_EV_vs_WT_F05.14551.14551.3 2.39E-07 13/40 R.LDHKFDLMYAK.R "sp|Q9NY65|TBA8_HUMAN,sp|P0DPH7|TBA3C_HUMAN,sp|Q71U36|TBA1A_HUMAN,sp|P0DPH8|TBA3D_HUMAN,sp|A6NHL2|TBAL3_HUMAN,sp|P68366|TBA4A_HUMAN,sp|P68363|TBA1B_HUMAN,sp|Q9BQE3|TBA1C_HUMAN,tr|F5H5D3|F5H5D3_HUMAN,tr|C9J2C0|C9J2C0_HUMAN,tr|V9GZ17|V9GZ17_HUMAN,tr|A0A7P0T945|A0A7P0T945_HUMAN" 12 1379.6908 0.52 66265 14551 3 1379.685178 460.9042 Tubulin alpha-8 chain OS=Homo sapiens OX=9606 GN=TUBA8 PE=1 SV=1 6.75 2644.2 - 1.38E+06 - - - -4.0444 - 2.636 0.491 - 277.1 1 2 1 -0.0056 11 0 0 0 2.67E+07 5.12E+07 - - - 6.7661 0.9998 221125_WJC_METTL3_EV_vs_WT_F05.14552.14552.2 4.83E-08 13/30 K.GGK[136.11]PEPPAMPQPVPTA.- "sp|P23396|RS3_HUMAN,tr|H0YEU2|H0YEU2_HUMAN,tr|E9PL09|E9PL09_HUMAN,tr|E9PPU1|E9PPU1_HUMAN" 4 1580.8112 0.83 66266 14552 2 1580.808489 791.4129 40S ribosomal protein S3 OS=Homo sapiens OX=9606 GN=RPS3 PE=1 SV=2 6 2644.3 - 842328 - - - -1.7238 - 2.217 0.558 - 268.1 1 2 0 -0.0027 16 0 0 0 1.29E+08 1.55E+08 - - - 5.1189 0.9989 221125_WJC_METTL3_EV_vs_WT_F05.14554.14554.3 9.20E-06 14/40 R.HNLSLNEC[160.03]FVK[136.11].V "sp|O43638|FOXS1_HUMAN,sp|Q12948|FOXC1_HUMAN,sp|Q99958|FOXC2_HUMAN" 3 1367.6747 2.34 66268 14554 3 1367.667335 456.8989 Forkhead box protein S1 OS=Homo sapiens OX=9606 GN=FOXS1 PE=2 SV=2 6.74 2644.6 - 726917 - - - -5.4004 - 2.369 0.441 - 359.1 1 2 0 -0.0074 11 0 0 0 2.89E+07 1.24E+07 - - - 5.9048 1 221125_WJC_METTL3_EV_vs_WT_F05.14556.14556.3 3.70E-08 20/68 R.LRPFVDGTAGASDPPC[160.03]VR.G "sp|Q14807|KIF22_HUMAN,tr|H3BQB9|H3BQB9_HUMAN" 2 1913.9418 0.75 66270 14556 3 1913.940111 638.9879 Kinesin-like protein KIF22 OS=Homo sapiens OX=9606 GN=KIF22 PE=1 SV=5 5.95 2644.8 - 430758 - - - -0.8725 - 3.427 0.469 - 304.6 1 2 0 -0.0017 18 0 0 0 3.91E+06 5.24E+06 - - - 6.8354 0.9999 221125_WJC_METTL3_EV_vs_WT_F05.14557.14557.2 7.54E-08 28-Nov R.SAADSISESVPVGPK.V sp|P45974|UBP5_HUMAN 1 1442.7253 1.28 66271 14557 2 1442.725489 722.3699 Ubiquitin carboxyl-terminal hydrolase 5 OS=Homo sapiens OX=9606 GN=USP5 PE=1 SV=2 4.37 2645 - 388639 - - - 0.1386 - 2.5 0.571 - 336.4 1 2 0 0.0002 15 0 0 0 7.98E+06 6.22E+06 - - - 5.5111 0.9473 221125_WJC_METTL3_EV_vs_WT_F05.14561.14561.3 0.0572 Oct-40 R.TFDEFQELHNK.L sp|O00443|P3C2A_HUMAN 1 1406.6466 0.7 66273 14561 3 1406.640727 469.8895 Phosphatidylinositol 4-phosphate 3-kinase C2 domain-containing subunit alpha OS=Homo sapiens OX=9606 GN=PIK3C2A PE=1 SV=2 4.65 2645.4 - 1.69E+06 - - - -4.2065 - 1.585 0.203 - 84 1 2 0 -0.0059 11 0 0 0 1.62E+07 2.30E+07 - - - 2.1101 0.999 221125_WJC_METTL3_EV_vs_WT_F05.14562.14562.3 0.00372 Oct-40 R.TFDEFQELHNK[136.11].L sp|O00443|P3C2A_HUMAN 1 1414.6608 1.2 66274 14562 3 1414.659428 472.5609 Phosphatidylinositol 4-phosphate 3-kinase C2 domain-containing subunit alpha OS=Homo sapiens OX=9606 GN=PIK3C2A PE=1 SV=2 4.65 2645.5 - 1.86E+06 - - - -1.0009 - 1.627 0.304 - 99 1 2 0 -0.0014 11 0 0 0 1.61E+07 1.34E+07 - - - 3.3116 1 221125_WJC_METTL3_EV_vs_WT_F05.14563.14563.2 5.73E-11 16/20 R.HNLSLNEC[160.03]FVK.V "sp|O43638|FOXS1_HUMAN,sp|Q12948|FOXC1_HUMAN,sp|Q99958|FOXC2_HUMAN" 3 1359.6605 1.93 66275 14563 2 1359.658138 680.8375 Forkhead box protein S1 OS=Homo sapiens OX=9606 GN=FOXS1 PE=2 SV=2 6.74 2645.6 - 1.62E+06 - - - -1.7526 - 3.332 0.652 - 649.8 1 2 0 -0.0024 11 0 0 0 1.80E+07 9.35E+06 - - - 7.1119 0.9999 221125_WJC_METTL3_EV_vs_WT_F05.14564.14564.3 5.90E-08 19/60 R.VLSR[166.11]PNAQELPSMYQR[166.11].L "sp|Q99623|PHB2_HUMAN,tr|F5H3X6|F5H3X6_HUMAN,tr|A0A7I2V5F0|A0A7I2V5F0_HUMAN,tr|F5GWA7|F5GWA7_HUMAN,tr|J3KPX7|J3KPX7_HUMAN,tr|F5GY37|F5GY37_HUMAN" 6 1907.9791 1.12 66276 14564 3 1907.979681 637.0003 Prohibitin-2 OS=Homo sapiens OX=9606 GN=PHB2 PE=1 SV=2 8.72 2645.7 - 1.70E+06 - - - 0.3276 - 2.796 0.384 - 338.1 1 2 0 0.0006 16 0 0 0 9.09E+07 8.12E+07 - - - 5.4592 1 221125_WJC_METTL3_EV_vs_WT_F05.14565.14565.3 7.81E-06 17/44 K.VNGR[166.11]PLEMIEPR[166.11].T "sp|P62249|RS16_HUMAN,tr|M0R3H0|M0R3H0_HUMAN,tr|M0R1M5|M0R1M5_HUMAN,tr|Q6IPX4|Q6IPX4_HUMAN" 4 1429.7615 1.26 66277 14565 3 1429.759453 477.5944 40S ribosomal protein S16 OS=Homo sapiens OX=9606 GN=RPS16 PE=1 SV=2 6.11 2645.8 - 1.22E+06 - - - -1.403 - 2.686 0.474 - 372.2 1 2 0 -0.002 12 0 0 0 1.03E+07 8.16E+06 - - - 6.5628 0.9996 221125_WJC_METTL3_EV_vs_WT_F05.14566.14566.2 1.25E-08 14/30 K.GGKPEPPAMPQPVPTA.- "sp|P23396|RS3_HUMAN,tr|H0YEU2|H0YEU2_HUMAN,tr|E9PL09|E9PL09_HUMAN,tr|E9PPU1|E9PPU1_HUMAN" 4 1572.797 0.83 66278 14566 2 1572.792575 787.4058 40S ribosomal protein S3 OS=Homo sapiens OX=9606 GN=RPS3 PE=1 SV=2 6 2646 - 1.17E+06 - - - -2.8224 - 2.222 0.576 - 276.7 1 2 0 -0.0044 16 0 0 0 1.29E+08 1.55E+08 - - - 5.2569 1 221125_WJC_METTL3_EV_vs_WT_F05.14567.14567.2 0.0696 16/20 R.HNLSLNEC[160.03]FVK[136.11].V "sp|O43638|FOXS1_HUMAN,sp|Q12948|FOXC1_HUMAN,sp|Q99958|FOXC2_HUMAN" 3 1367.6747 1.93 66279 14567 2 1367.672758 684.8446 Forkhead box protein S1 OS=Homo sapiens OX=9606 GN=FOXS1 PE=2 SV=2 6.74 2646.1 - 832192 - - - -1.4353 - 3.468 0.467 - 623.9 1 2 0 -0.002 11 0 0 0 1.80E+07 9.35E+06 - - - 5.8538 0.9999 221125_WJC_METTL3_EV_vs_WT_F05.14568.14568.3 3.95E-06 Dec-40 K.HETEFAELEVK.T "sp|O95619|YETS4_HUMAN,tr|F8W0J4|F8W0J4_HUMAN" 2 1330.6405 0.82 66280 14568 3 1330.638502 444.5541 YEATS domain-containing protein 4 OS=Homo sapiens OX=9606 GN=YEATS4 PE=1 SV=1 4.48 2646.2 - 761580 - - - -1.4985 - 2.174 0.443 - 214.6 1 2 0 -0.002 11 0 0 0 1.22E+07 1.48E+07 - - - 5.6846 1 221125_WJC_METTL3_EV_vs_WT_F05.14576.14576.3 0.00046 21/60 R.VLSRPNAQELPSMYQR.L "sp|Q99623|PHB2_HUMAN,tr|F5H3X6|F5H3X6_HUMAN,tr|A0A7I2V5F0|A0A7I2V5F0_HUMAN,tr|F5GWA7|F5GWA7_HUMAN,tr|J3KPX7|J3KPX7_HUMAN,tr|F5GY37|F5GY37_HUMAN" 6 1887.9625 1.11 66287 14576 3 1887.964847 630.3281 Prohibitin-2 OS=Homo sapiens OX=9606 GN=PHB2 PE=1 SV=2 8.72 2647 - 2.07E+06 - - - 1.2347 - 3.571 0.42 - 460.7 1 2 0 0.0023 16 0 0 0 9.11E+07 8.21E+07 - - - 6.4879 0.9997 221125_WJC_METTL3_EV_vs_WT_F05.14577.14577.3 0.0126 Nov-40 K.IWHHTFYNELR[166.11].V "sp|Q6S8J3|POTEE_HUMAN,sp|P63261|ACTG_HUMAN,sp|P68133|ACTS_HUMAN,sp|Q9BYX7|ACTBM_HUMAN,sp|P68032|ACTC_HUMAN,sp|P60709|ACTB_HUMAN,sp|A5A3E0|POTEF_HUMAN,sp|P0CG38|POTEI_HUMAN,sp|P0CG39|POTEJ_HUMAN,tr|A0A804GS07|A0A804GS07_HUMAN,tr|I3L3I0|I3L3I0_HUMAN,tr|G5E9R0|G5E9R0_HUMAN,tr|E7EVS6|E7EVS6_HUMAN,tr|A0A6Q8PFE4|A0A6Q8PFE4_HUMAN,tr|J3KT65|J3KT65_HUMAN,tr|I3L3R2|I3L3R2_HUMAN,tr|K7EM38|K7EM38_HUMAN,tr|A0A6Q8PH58|A0A6Q8PH58_HUMAN,tr|I3L1U9|I3L1U9_HUMAN,tr|A0A804HKV3|A0A804HKV3_HUMAN,tr|A0A2R8Y793|A0A2R8Y793_HUMAN,tr|I3L4N8|I3L4N8_HUMAN,tr|C9JUM1|C9JUM1_HUMAN,tr|C9JZR7|C9JZR7_HUMAN,tr|A0A2R8YGF8|A0A2R8YGF8_HUMAN,tr|A6NL76|A6NL76_HUMAN" 26 1524.7502 0.93 66288 14577 3 1524.745622 509.2573 POTE ankyrin domain family member E OS=Homo sapiens OX=9606 GN=POTEE PE=2 SV=3 6.92 2647.1 - 1.32E+06 - - - -2.971 - 2.164 0.429 - 199.4 1 2 0 -0.0045 11 0 0 0 2.08E+08 2.23E+08 - - - 5.5147 0.9999 221125_WJC_METTL3_EV_vs_WT_F05.14579.14579.3 0.000254 13/40 K.IWHHTFYNELR.V "sp|Q6S8J3|POTEE_HUMAN,sp|P63261|ACTG_HUMAN,sp|P68133|ACTS_HUMAN,sp|Q9BYX7|ACTBM_HUMAN,sp|P68032|ACTC_HUMAN,sp|P60709|ACTB_HUMAN,sp|A5A3E0|POTEF_HUMAN,sp|P0CG38|POTEI_HUMAN,sp|P0CG39|POTEJ_HUMAN,tr|A0A804GS07|A0A804GS07_HUMAN,tr|I3L3I0|I3L3I0_HUMAN,tr|G5E9R0|G5E9R0_HUMAN,tr|E7EVS6|E7EVS6_HUMAN,tr|A0A6Q8PFE4|A0A6Q8PFE4_HUMAN,tr|J3KT65|J3KT65_HUMAN,tr|I3L3R2|I3L3R2_HUMAN,tr|K7EM38|K7EM38_HUMAN,tr|A0A6Q8PH58|A0A6Q8PH58_HUMAN,tr|I3L1U9|I3L1U9_HUMAN,tr|A0A804HKV3|A0A804HKV3_HUMAN,tr|A0A2R8Y793|A0A2R8Y793_HUMAN,tr|I3L4N8|I3L4N8_HUMAN,tr|C9JUM1|C9JUM1_HUMAN,tr|C9JZR7|C9JZR7_HUMAN,tr|A0A2R8YGF8|A0A2R8YGF8_HUMAN,tr|A6NL76|A6NL76_HUMAN" 26 1514.7419 0.93 66290 14579 3 1514.739313 505.9212 POTE ankyrin domain family member E OS=Homo sapiens OX=9606 GN=POTEE PE=2 SV=3 6.92 2647.4 - 894836 - - - -1.696 - 2.427 0.468 - 281.5 1 2 0 -0.0026 11 0 0 0 2.08E+08 2.23E+08 - - - 6.2759 1 221125_WJC_METTL3_EV_vs_WT_F05.14580.14580.2 1.06E-05 15/18 K.HYWEVDVTGK.E sp|P19474|RO52_HUMAN 1 1232.5826 1.38 66291 14580 2 1232.579582 617.2986 E3 ubiquitin-protein ligase TRIM21 OS=Homo sapiens OX=9606 GN=TRIM21 PE=1 SV=1 5.32 2647.5 - 603284 - - - -2.4388 - 3.018 0.578 - 887.1 1 2 0 -0.003 10 0 0 0 2.00E+07 1.45E+07 - - - 6.3924 0.9995 221125_WJC_METTL3_EV_vs_WT_F05.14581.14581.2 6.25E-06 13/28 R.SAADSISESVPVGPK[136.11].V sp|P45974|UBP5_HUMAN 1 1450.7395 1.28 66292 14581 2 1450.734648 726.377 Ubiquitin carboxyl-terminal hydrolase 5 OS=Homo sapiens OX=9606 GN=USP5 PE=1 SV=2 4.37 2647.6 - 535197 - - - -3.3369 - 2.636 0.574 - 492.5 1 2 0 -0.0048 15 0 0 0 7.98E+06 6.22E+06 - - - 5.662 0.9997 221125_WJC_METTL3_EV_vs_WT_F05.14582.14582.2 0.00116 15/30 R.AITDGQAGFGNDTLSK[136.11].V "sp|Q7Z739|YTHD3_HUMAN,tr|A0A087X0Q1|A0A087X0Q1_HUMAN,tr|A0A024R7W5|A0A024R7W5_HUMAN,tr|A0A087WY31|A0A087WY31_HUMAN" 4 1601.7777 1.28 66293 14582 2 1601.78134 801.8961 YTH domain-containing family protein 3 OS=Homo sapiens OX=9606 GN=YTHDF3 PE=1 SV=1 4.21 2647.8 - 527673 - - - 2.2943 - 2.966 0.443 - 531.2 1 2 0 0.0037 16 0 0 0 2.30E+07 1.80E+07 - - - 4.9848 0.9996 221125_WJC_METTL3_EV_vs_WT_F05.14587.14587.3 0.0023 Nov-40 K.ENDIKPLTSFR.Q "sp|Q14739|LBR_HUMAN,tr|A0A494C1L1|A0A494C1L1_HUMAN,tr|C9JXK0|C9JXK0_HUMAN" 3 1318.6881 1.19 66297 14587 3 1318.686136 440.57 Delta(14)-sterol reductase LBR OS=Homo sapiens OX=9606 GN=LBR PE=1 SV=2 6.17 2648.4 - 1.33E+06 - - - -1.5007 - 1.813 0.36 - 176.7 1 2 0 -0.002 11 0 0 0 3.39E+07 2.84E+07 - - - 4.2433 1 221125_WJC_METTL3_EV_vs_WT_F05.14588.14588.2 5.32E-08 16/30 R.AITDGQAGFGNDTLSK.V "sp|Q7Z739|YTHD3_HUMAN,tr|A0A087X0Q1|A0A087X0Q1_HUMAN,tr|A0A024R7W5|A0A024R7W5_HUMAN,tr|A0A087WY31|A0A087WY31_HUMAN" 4 1593.7635 1.31 66298 14588 2 1593.763127 797.889 YTH domain-containing family protein 3 OS=Homo sapiens OX=9606 GN=YTHDF3 PE=1 SV=1 4.21 2648.5 - 1.08E+06 - - - -0.2121 - 3.414 0.587 - 719.6 1 2 0 -0.0003 16 0 0 0 2.36E+07 1.80E+07 - - - 6.3953 0.9991 221125_WJC_METTL3_EV_vs_WT_F05.14589.14589.3 0.00502 17/60 K.AHLMEIQVNGGTVAEK[136.11].L "sp|P39023|RL3_HUMAN,tr|G5E9G0|G5E9G0_HUMAN,tr|H7C3M2|H7C3M2_HUMAN,tr|B5MCW2|B5MCW2_HUMAN,tr|H7C422|H7C422_HUMAN" 5 1703.8756 1.11 66299 14589 3 1703.875866 568.9658 60S ribosomal protein L3 OS=Homo sapiens OX=9606 GN=RPL3 PE=1 SV=2 5.4 2648.6 - 1.04E+06 - - - 0.1532 - 2.009 0.277 - 264.8 1 2 0 0.0003 16 0 0 0 2.14E+07 1.93E+07 - - - 3.4182 0.9982 221125_WJC_METTL3_EV_vs_WT_F05.14590.14590.4 0.00449 15/60 K.IWHHTFYNELR[166.11].V "sp|Q6S8J3|POTEE_HUMAN,sp|P63261|ACTG_HUMAN,sp|P68133|ACTS_HUMAN,sp|Q9BYX7|ACTBM_HUMAN,sp|P68032|ACTC_HUMAN,sp|P60709|ACTB_HUMAN,sp|A5A3E0|POTEF_HUMAN,sp|P0CG38|POTEI_HUMAN,sp|P0CG39|POTEJ_HUMAN,tr|A0A804GS07|A0A804GS07_HUMAN,tr|I3L3I0|I3L3I0_HUMAN,tr|G5E9R0|G5E9R0_HUMAN,tr|E7EVS6|E7EVS6_HUMAN,tr|A0A6Q8PFE4|A0A6Q8PFE4_HUMAN,tr|J3KT65|J3KT65_HUMAN,tr|I3L3R2|I3L3R2_HUMAN,tr|K7EM38|K7EM38_HUMAN,tr|A0A6Q8PH58|A0A6Q8PH58_HUMAN,tr|I3L1U9|I3L1U9_HUMAN,tr|A0A804HKV3|A0A804HKV3_HUMAN,tr|A0A2R8Y793|A0A2R8Y793_HUMAN,tr|I3L4N8|I3L4N8_HUMAN,tr|C9JUM1|C9JUM1_HUMAN,tr|C9JZR7|C9JZR7_HUMAN,tr|A0A2R8YGF8|A0A2R8YGF8_HUMAN,tr|A6NL76|A6NL76_HUMAN" 26 1524.7502 0.02 66300 14590 4 1524.746646 382.1948 POTE ankyrin domain family member E OS=Homo sapiens OX=9606 GN=POTEE PE=2 SV=3 6.92 2648.7 - 944924 - - - -2.2994 - 1.951 0.295 - 174.6 1 2 0 -0.0035 11 0 0 0 1.77E+06 7.85E+07 - - - 2.0514 0.9994 221125_WJC_METTL3_EV_vs_WT_F05.14595.14595.3 4.66E-06 18/64 K.EVIAVSC[160.03]GPAQC[160.03]QETIR.T sp|P38117|ETFB_HUMAN 1 1916.9084 2.09 66305 14595 3 1916.896989 639.9768 Electron transfer flavoprotein subunit beta OS=Homo sapiens OX=9606 GN=ETFB PE=1 SV=3 4.53 2649.4 - 549188 - - - -5.9695 - 3.301 0.509 - 307.3 1 2 0 -0.0114 17 0 0 0 6.55E+06 3.13E+06 - - - 7.2287 0.9998 221125_WJC_METTL3_EV_vs_WT_F05.14596.14596.2 7.18E-07 14/28 R.AGTGVDNVDLEAATR.K "sp|O43175|SERA_HUMAN,tr|A0A2C9F2M7|A0A2C9F2M7_HUMAN,tr|A0A286YFB2|A0A286YFB2_HUMAN,tr|A0A286YFC8|A0A286YFC8_HUMAN,tr|A0A286YF22|A0A286YF22_HUMAN,tr|A0A286YFL2|A0A286YFL2_HUMAN,tr|A0A286YFA2|A0A286YFA2_HUMAN,tr|A0A286YFM8|A0A286YFM8_HUMAN,tr|A0A286YER3|A0A286YER3_HUMAN" 9 1487.7216 999 66306 14596 2 1487.718138 744.8681 D-3-phosphoglycerate dehydrogenase OS=Homo sapiens OX=9606 GN=PHGDH PE=1 SV=4 4.03 2649.5 - 505621 - - - -2.327 - 2.609 0.582 - 603.1 1 2 0 -0.0035 15 0 0 0 3.11E+06 0.00E+00 - - - 5.6962 1 221125_WJC_METTL3_EV_vs_WT_F05.14597.14597.2 1.58E-07 28-Oct R.AFQLEEGEETEPDC[160.03]K[136.11].Y sp|P38432|COIL_HUMAN 1 1788.7604 1.17 66307 14597 2 1788.756202 895.3875 Coilin OS=Homo sapiens OX=9606 GN=COIL PE=1 SV=1 3.83 2649.6 - 376995 - - - -2.3245 - 2.337 0.643 - 220.6 1 2 0 -0.0042 15 0 0 0 5.00E+06 4.26E+06 - - - 5.8759 0.9917 221125_WJC_METTL3_EV_vs_WT_F05.14600.14600.2 9.37E-05 22-Oct K.DHTPSQELALTQ.S "sp|Q86U44|MTA70_HUMAN,tr|H0YFV6|H0YFV6_HUMAN" 2 1338.6416 - 66308 14600 2 1338.640221 670.3281 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 4.35 2650 - 5.93E+07 - - - -0.9995 - 2.245 0.51 - 356.7 1 1 0 -0.0013 12 0 0 0 - - - - - 4.9353 0.9996 221125_WJC_METTL3_EV_vs_WT_F05.14602.14602.3 0.00226 Sep-40 K.ENDIK[136.11]PLTSFR[166.11].Q "sp|Q14739|LBR_HUMAN,tr|A0A494C1L1|A0A494C1L1_HUMAN,tr|C9JXK0|C9JXK0_HUMAN" 3 1336.7106 1.24 66310 14602 3 1336.708561 446.5775 Delta(14)-sterol reductase LBR OS=Homo sapiens OX=9606 GN=LBR PE=1 SV=2 6.17 2650.1 - 2.65E+06 - - - -1.5142 - 1.916 0.341 - 121.6 1 2 0 -0.002 11 0 0 0 3.55E+07 2.86E+07 - - - 4.1885 0.9999 221125_WJC_METTL3_EV_vs_WT_F05.14603.14603.3 0.000364 13/40 R.LDHK[136.11]FDLMYAK[136.11].R "sp|Q9NY65|TBA8_HUMAN,sp|P0DPH7|TBA3C_HUMAN,sp|Q71U36|TBA1A_HUMAN,sp|P0DPH8|TBA3D_HUMAN,sp|A6NHL2|TBAL3_HUMAN,sp|P68366|TBA4A_HUMAN,sp|P68363|TBA1B_HUMAN,sp|Q9BQE3|TBA1C_HUMAN,tr|F5H5D3|F5H5D3_HUMAN,tr|C9J2C0|C9J2C0_HUMAN,tr|V9GZ17|V9GZ17_HUMAN,tr|A0A7P0T945|A0A7P0T945_HUMAN" 12 1395.7192 0.52 66311 14603 3 1395.71863 466.247 Tubulin alpha-8 chain OS=Homo sapiens OX=9606 GN=TUBA8 PE=1 SV=1 6.75 2650.2 - 2.38E+06 - - - -0.3783 - 2.729 0.491 - 294.2 1 2 1 -0.0005 11 0 0 0 2.67E+07 5.12E+07 - - - 6.866 0.9801 221125_WJC_METTL3_EV_vs_WT_F05.14605.14605.2 0.0282 24-Oct R.AETEC[160.03]QNTEYQQL.L "sp|P13645|K1C10_HUMAN,tr|A0A1B0GVI3|A0A1B0GVI3_HUMAN" 2 1612.6675 - 66313 14605 2 1612.668809 807.341 "Keratin, type I cytoskeletal 10 OS=Homo sapiens OX=9606 GN=KRT10 PE=1 SV=6" 3.67 2650.4 - 1.29E+06 - - - 0.8018 - 1.7 0.441 - 204.3 1 1 0 0.0013 13 0 0 0 - - - - - 3.6597 1 221125_WJC_METTL3_EV_vs_WT_F05.14607.14607.2 0.000674 13/28 R.AFQLEEGEETEPDC[160.03]K.Y sp|P38432|COIL_HUMAN 1 1780.7462 1.17 66315 14607 2 1780.74717 891.3804 Coilin OS=Homo sapiens OX=9606 GN=COIL PE=1 SV=1 3.83 2650.6 - 474844 - - - 0.5672 - 2.621 0.622 - 395.6 1 2 0 0.001 15 0 0 0 5.00E+06 4.26E+06 - - - 6.0037 0.9998 221125_WJC_METTL3_EV_vs_WT_F05.14611.14611.2 4.12E-07 13/18 K.HYWEVDVTGK[136.11].E sp|P19474|RO52_HUMAN 1 1240.5968 1.38 66317 14611 2 1240.59534 621.3057 E3 ubiquitin-protein ligase TRIM21 OS=Homo sapiens OX=9606 GN=TRIM21 PE=1 SV=1 5.32 2651.2 - 1.36E+06 - - - -1.1672 - 2.988 0.383 - 582.2 1 2 0 -0.0014 10 0 0 0 2.01E+07 1.46E+07 - - - 4.9248 0.9999 221125_WJC_METTL3_EV_vs_WT_F05.14612.14612.3 0.00745 13/44 K.STVTLSWKPVQK.V "sp|Q9BZZ5|API5_HUMAN,tr|H0YER7|H0YER7_HUMAN,tr|G3V1C3|G3V1C3_HUMAN" 3 1372.7715 2.78 66318 14612 3 1372.770253 458.5978 Apoptosis inhibitor 5 OS=Homo sapiens OX=9606 GN=API5 PE=1 SV=3 10 2651.3 - 1.54E+06 - - - -0.8727 - 2.461 0.399 - 293.4 1 2 0 -0.0012 12 0 0 0 2.44E+07 8.77E+06 - - - 5.4844 1 221125_WJC_METTL3_EV_vs_WT_F05.14613.14613.3 0.000173 16/60 K.AHLMEIQVNGGTVAEK.L "sp|P39023|RL3_HUMAN,tr|G5E9G0|G5E9G0_HUMAN,tr|H7C3M2|H7C3M2_HUMAN,tr|B5MCW2|B5MCW2_HUMAN,tr|H7C422|H7C422_HUMAN" 5 1695.8614 1.11 66319 14613 3 1695.860784 566.2944 60S ribosomal protein L3 OS=Homo sapiens OX=9606 GN=RPL3 PE=1 SV=2 5.4 2651.3 - 2.32E+06 - - - -0.3662 - 3.022 0.499 - 403.5 1 2 0 -0.0006 16 0 0 0 2.16E+07 1.96E+07 - - - 6.9408 0.9998 221125_WJC_METTL3_EV_vs_WT_F05.14614.14614.2 9.85E-07 13/30 R.ELNNSTNGIVIEPSEK[136.11].A "sp|Q14681|KCTD2_HUMAN,tr|J3QSC8|J3QSC8_HUMAN" 2 1750.8829 7 66320 14614 2 1750.884543 876.4487 BTB\POZ domain-containing protein KCTD2 OS=Homo sapiens OX=9606 GN=KCTD2 PE=1 SV=3 4.25 2651.4 - 2.01E+06 - - - 0.9618 - 2.102 0.523 - 358.6 1 2 0 0.0017 16 0 0 0 2.64E+08 3.77E+07 - - - 4.7298 1 221125_WJC_METTL3_EV_vs_WT_F05.14615.14615.3 0.0343 17/52 K.R[166.11]PSPDEPMTNLELK[136.11].L "sp|Q9UHD1|CHRD1_HUMAN,tr|E9PPQ5|E9PPQ5_HUMAN" 2 1643.8308 0.29 66321 14615 3 1643.829804 548.9509 Cysteine and histidine-rich domain-containing protein 1 OS=Homo sapiens OX=9606 GN=CHORDC1 PE=1 SV=2 4.68 2651.5 - 1.27E+06 - - - -0.5919 - 3.294 0.464 - 437.7 1 2 0 -0.001 14 0 0 0 4.53E+06 1.58E+07 - - - 6.8809 0.9972 221125_WJC_METTL3_EV_vs_WT_F05.14616.14616.3 0.0111 Dec-60 K.GGK[136.11]PEPPAMPQPVPTA.- "sp|P23396|RS3_HUMAN,tr|H0YEU2|H0YEU2_HUMAN,tr|E9PL09|E9PL09_HUMAN,tr|E9PPU1|E9PPU1_HUMAN" 4 1580.8112 0.62 66322 14616 3 1580.814344 527.9443 40S ribosomal protein S3 OS=Homo sapiens OX=9606 GN=RPS3 PE=1 SV=2 6 2651.6 - 781513 - - - 1.98 - 1.761 0.274 - 133 1 2 0 0.0031 16 0 0 0 2.78E+07 4.46E+07 - - - 3.0459 1 221125_WJC_METTL3_EV_vs_WT_F05.14618.14618.3 3.79E-05 16/60 K.GGKPEPPAMPQPVPTA.- "sp|P23396|RS3_HUMAN,tr|H0YEU2|H0YEU2_HUMAN,tr|E9PL09|E9PL09_HUMAN,tr|E9PPU1|E9PPU1_HUMAN" 4 1572.797 0.63 66324 14618 3 1572.795122 525.2729 40S ribosomal protein S3 OS=Homo sapiens OX=9606 GN=RPS3 PE=1 SV=2 6 2651.9 - 683351 - - - -1.203 - 2.405 0.533 - 279.4 1 2 0 -0.0019 16 0 0 0 2.77E+07 4.40E+07 - - - 6.7336 0.9825 221125_WJC_METTL3_EV_vs_WT_F05.14619.14619.2 5.02 12-Jul R.SIFDHIK.L "sp|Q9NYF8|BCLF1_HUMAN,tr|E9PKI6|E9PKI6_HUMAN,tr|A0A1W2PQ43|A0A1W2PQ43_HUMAN,tr|E9PK91|E9PK91_HUMAN,tr|E9PJA7|E9PJA7_HUMAN,tr|E9PK09|E9PK09_HUMAN,tr|E9PQN2|E9PQN2_HUMAN" 7 858.46 2.03 66325 14619 2 858.460738 430.2373 Bcl-2-associated transcription factor 1 OS=Homo sapiens OX=9606 GN=BCLAF1 PE=1 SV=2 6.46 2652 - 611069 - - - 0.9144 - 1.107 0.141 - 122.7 1 2 0 0.0008 7 0 0 0 1.51E+07 7.43E+06 - - - 0.4043 0.9998 221125_WJC_METTL3_EV_vs_WT_F05.14620.14620.3 0.000301 Dec-48 R.NEYGPVLHMPTSK.E "sp|O43660|PLRG1_HUMAN,tr|D6RA26|D6RA26_HUMAN,tr|B7Z982|B7Z982_HUMAN" 3 1471.713 999 66326 14620 3 1471.713815 491.5783 Pleiotropic regulator 1 OS=Homo sapiens OX=9606 GN=PLRG1 PE=1 SV=1 6.75 2652.1 - 424149 - - - 0.5878 - 2.066 0.381 - 154.1 1 2 0 0.0009 13 0 0 0 4.99E+06 0.00E+00 - - - 4.7549 0.9992 221125_WJC_METTL3_EV_vs_WT_F05.14621.14621.3 0.0168 Nov-36 K.SYQEELDKLR.Q sp|Q5T1M5|FKB15_HUMAN 1 1279.6408 2.2 66327 14621 3 1279.64109 427.5542 FK506-binding protein 15 OS=Homo sapiens OX=9606 GN=FKBP15 PE=1 SV=2 4.68 2652.3 - 284604 - - - 0.2024 - 1.757 0.405 - 165.4 1 2 1 0.0003 10 0 0 0 6.24E+06 2.84E+06 - - - 4.7013 0.9997 221125_WJC_METTL3_EV_vs_WT_F05.14622.14622.3 0.000163 Sep-40 R.LLASTLVHSVK[136.11].K "sp|Q9NYF8|BCLF1_HUMAN,tr|E9PKI6|E9PKI6_HUMAN,tr|A0A1W2PQ43|A0A1W2PQ43_HUMAN,tr|E9PK91|E9PK91_HUMAN,tr|E9PJA7|E9PJA7_HUMAN,tr|E9PK09|E9PK09_HUMAN,tr|E9PQN2|E9PQN2_HUMAN" 7 1174.7165 1.99 66328 14622 3 1174.71369 392.5794 Bcl-2-associated transcription factor 1 OS=Homo sapiens OX=9606 GN=BCLAF1 PE=1 SV=2 8.76 2652.4 - 253421 - - - -2.3997 - 2.109 0.393 - 64.1 1 2 0 -0.0028 11 0 0 0 2.14E+07 1.08E+07 - - - 5.0406 1 221125_WJC_METTL3_EV_vs_WT_F05.14626.14626.3 2.54E-08 16/44 R.QQLQQVPGLLHR[166.11].M sp|Q14166|TTL12_HUMAN 1 1425.808 0.51 66330 14626 3 1425.807664 476.2766 Tubulin--tyrosine ligase-like protein 12 OS=Homo sapiens OX=9606 GN=TTLL12 PE=1 SV=2 9.76 2652.9 - 869711 - - - -0.2364 - 2.729 0.534 - 406.3 1 2 0 -0.0003 12 0 0 0 5.43E+06 1.07E+07 - - - 7.2762 1 221125_WJC_METTL3_EV_vs_WT_F05.14627.14627.3 3.59E-06 17/48 K.KTGQPMINLYTDR.E "sp|P35637|FUS_HUMAN,tr|H3BPE7|H3BPE7_HUMAN" 2 1535.7766 1.15 66331 14627 3 1535.773916 512.9328 RNA-binding protein FUS OS=Homo sapiens OX=9606 GN=FUS PE=1 SV=1 8.59 2653 - 2.86E+06 - - - -1.7561 - 3.31 0.51 - 630.5 1 2 0 -0.0027 13 0 0 0 1.70E+08 1.47E+08 - - - 7.4705 0.9999 221125_WJC_METTL3_EV_vs_WT_F05.14628.14628.3 7.08E-10 15/60 K.AVEEEDKMTPEQLAIK.N sp|O00487|PSDE_HUMAN 1 1829.9081 0.64 66332 14628 3 1829.910252 610.9766 26S proteasome non-ATPase regulatory subunit 14 OS=Homo sapiens OX=9606 GN=PSMD14 PE=1 SV=1 4.25 2653.1 - 907213 - - - 1.1864 - 2.813 0.594 - 183.5 1 2 1 0.0022 16 0 0 0 1.22E+07 1.92E+07 - - - 7.8157 0.9997 221125_WJC_METTL3_EV_vs_WT_F05.14629.14629.3 0.00497 14/40 R.LLASTLVHSVK.K "sp|Q9NYF8|BCLF1_HUMAN,tr|E9PKI6|E9PKI6_HUMAN,tr|A0A1W2PQ43|A0A1W2PQ43_HUMAN,tr|E9PK91|E9PK91_HUMAN,tr|E9PJA7|E9PJA7_HUMAN,tr|E9PK09|E9PK09_HUMAN,tr|E9PQN2|E9PQN2_HUMAN" 7 1166.7023 2 66333 14629 3 1166.700689 389.908 Bcl-2-associated transcription factor 1 OS=Homo sapiens OX=9606 GN=BCLAF1 PE=1 SV=2 8.76 2653.2 - 851720 - - - -1.3885 - 2.553 0.284 - 154.3 1 2 0 -0.0016 11 0 0 0 2.15E+07 1.08E+07 - - - 4.3685 0.9999 221125_WJC_METTL3_EV_vs_WT_F05.14630.14630.3 0.000229 14/44 K.STVTLSWK[136.11]PVQK[136.11].V "sp|Q9BZZ5|API5_HUMAN,tr|H0YER7|H0YER7_HUMAN,tr|G3V1C3|G3V1C3_HUMAN" 3 1388.7999 2.79 66334 14630 3 1388.799315 463.9406 Apoptosis inhibitor 5 OS=Homo sapiens OX=9606 GN=API5 PE=1 SV=3 10 2653.4 - 773413 - - - -0.3859 - 2.463 0.41 - 342.1 1 2 0 -0.0005 12 0 0 0 2.44E+07 8.77E+06 - - - 5.6094 0.9999 221125_WJC_METTL3_EV_vs_WT_F05.14631.14631.3 8.95E-07 15/52 R.QEEEMMAKEEELVK.V sp|P35579|MYH9_HUMAN 1 1721.7852 0.79 66335 14631 3 1721.783355 574.9357 Myosin-9 OS=Homo sapiens OX=9606 GN=MYH9 PE=1 SV=4 4.21 2653.5 - 726261 - - - -1.0646 - 2.649 0.505 - 302.9 1 2 1 -0.0018 14 0 0 0 7.64E+06 9.71E+06 - - - 6.7587 0.9999 221125_WJC_METTL3_EV_vs_WT_F05.14632.14632.3 0.00567 14/36 R.RIDISPSTFR.K "sp|Q9Y2W1|TR150_HUMAN,tr|A0A3B3ITZ9|A0A3B3ITZ9_HUMAN" 2 1190.6408 2.42 66336 14632 3 1190.640159 397.8875 Thyroid hormone receptor-associated protein 3 OS=Homo sapiens OX=9606 GN=THRAP3 PE=1 SV=2 9.6 2653.6 - 480017 - - - -0.514 - 2.504 0.36 - 415.7 1 2 0 -0.0006 10 0 0 0 2.39E+07 9.87E+06 - - - 5.2341 1 221125_WJC_METTL3_EV_vs_WT_F05.14633.14633.3 0.000165 Nov-60 K.WQPGEEPAGSVVQDSR[166.11].L "sp|Q9Y5K5|UCHL5_HUMAN,tr|Q5LJA9|Q5LJA9_HUMAN,tr|Q5LJB0|Q5LJB0_HUMAN,tr|Q5LJA5|Q5LJA5_HUMAN" 4 1750.815 1.61 66337 14633 3 1750.812542 584.6123 Ubiquitin carboxyl-terminal hydrolase isozyme L5 OS=Homo sapiens OX=9606 GN=UCHL5 PE=1 SV=3 4.14 2653.8 - 472471 - - - -1.4022 - 2.145 0.508 - 158.3 1 2 0 -0.0025 16 0 0 0 2.98E+07 1.86E+07 - - - 6.1611 0.9904 221125_WJC_METTL3_EV_vs_WT_F05.14634.14634.2 8.01E-06 26-Oct F.SSTSFGGSGMGNFK[136.11].S "sp|O75190|DNJB6_HUMAN,tr|A0A0J9YX62|A0A0J9YX62_HUMAN,tr|C9J2C4|C9J2C4_HUMAN" 3 1370.6016 1.01 66338 14634 2 1370.600839 686.3081 DnaJ homolog subfamily B member 6 OS=Homo sapiens OX=9606 GN=DNAJB6 PE=1 SV=2 8.47 2653.9 - 457624 - - - -0.5662 - 1.847 0.523 - 207 1 1 0 -0.0008 14 0 0 0 4.98E+06 4.91E+06 - - - 4.4433 0.9983 221125_WJC_METTL3_EV_vs_WT_F05.14636.14636.3 9.53E-05 Oct-44 K.DKVDVASVIVTK.L "sp|P61011|SRP54_HUMAN,tr|A0A7P0PJI2|A0A7P0PJI2_HUMAN,tr|G3V4F7|G3V4F7_HUMAN,tr|G3V480|G3V480_HUMAN,tr|A0A7I2V584|A0A7I2V584_HUMAN,tr|A0A7I2V5K0|A0A7I2V5K0_HUMAN" 6 1272.7289 0.97 66340 14636 3 1272.731039 425.2502 Signal recognition particle 54 kDa protein OS=Homo sapiens OX=9606 GN=SRP54 PE=1 SV=1 5.96 2654.1 - 249826 - - - 1.6673 - 2.191 0.335 - 213.5 1 2 1 0.0021 12 0 0 0 5.42E+06 5.61E+06 - - - 4.4485 0.9999 221125_WJC_METTL3_EV_vs_WT_F05.14639.14639.2 2.00E-06 22-Nov K.TEELEEESFPER[166.11].S "sp|Q9Y2W1|TR150_HUMAN,tr|A0A3B3ITZ9|A0A3B3ITZ9_HUMAN" 2 1503.6605 2.54 66341 14639 2 1503.659953 752.8375 Thyroid hormone receptor-associated protein 3 OS=Homo sapiens OX=9606 GN=THRAP3 PE=1 SV=2 3.9 2654.5 - 648290 - - - -0.3325 - 2.39 0.583 - 471 1 2 0 -0.0005 12 0 0 0 3.25E+07 1.28E+07 - - - 5.6394 0.9998 221125_WJC_METTL3_EV_vs_WT_F05.14640.14640.2 9.50E-06 13/24 R.EGVVQGVASVAEK[136.11].T sp|Q16143|SYUB_HUMAN 1 1279.6863 1.59 66342 14640 2 1279.687516 640.8504 Beta-synuclein OS=Homo sapiens OX=9606 GN=SNCB PE=1 SV=1 4.53 2654.7 - 518014 - - - 0.926 - 2.519 0.42 - 743.9 1 2 0 0.0012 13 0 0 0 7.44E+06 4.68E+06 - - - 4.5139 0.9992 221125_WJC_METTL3_EV_vs_WT_F05.14641.14641.3 0.00271 Oct-44 K.DKPTETLLNTVK.D sp|Q96SI9|STRBP_HUMAN 1 1357.7453 0.38 66343 14641 3 1357.745898 453.589 Spermatid perinuclear RNA-binding protein OS=Homo sapiens OX=9606 GN=STRBP PE=1 SV=1 6.07 2654.8 - 688081 - - - 0.4434 - 2.066 0.265 - 149.9 1 2 0 0.0006 12 0 0 0 7.77E+06 2.02E+07 - - - 3.5056 0.9997 221125_WJC_METTL3_EV_vs_WT_F05.14642.14642.3 0.0123 13/44 R.QQLQQVPGLLHR.M sp|Q14166|TTL12_HUMAN 1 1415.7997 0.51 66344 14642 3 1415.799278 472.9405 Tubulin--tyrosine ligase-like protein 12 OS=Homo sapiens OX=9606 GN=TTLL12 PE=1 SV=2 9.76 2654.9 - 657955 - - - -0.32 - 1.911 0.357 - 229.1 1 2 0 -0.0005 12 0 0 0 5.43E+06 1.07E+07 - - - 4.3152 1 221125_WJC_METTL3_EV_vs_WT_F05.14646.14646.3 1.95E-06 Oct-40 K.YC[160.03]FPNYVGRPK.H "sp|P61163|ACTZ_HUMAN,sp|P42025|ACTY_HUMAN,tr|R4GMT0|R4GMT0_HUMAN,tr|A0A1B0GVS3|A0A1B0GVS3_HUMAN" 4 1399.6707 0.92 66348 14646 3 1399.67266 467.5642 Alpha-centractin OS=Homo sapiens OX=9606 GN=ACTR1A PE=1 SV=1 9.2 2655.4 - 437099 - - - 1.4068 - 1.796 0.545 - 100.1 1 2 0 0.002 11 0 0 0 5.99E+06 6.52E+06 - - - 6.2791 0.9999 221125_WJC_METTL3_EV_vs_WT_F05.14647.14647.2 0.000149 20-Oct K.IWHHTFYNELR[166.11].V "sp|Q6S8J3|POTEE_HUMAN,sp|P63261|ACTG_HUMAN,sp|P68133|ACTS_HUMAN,sp|Q9BYX7|ACTBM_HUMAN,sp|P68032|ACTC_HUMAN,sp|P60709|ACTB_HUMAN,sp|A5A3E0|POTEF_HUMAN,sp|P0CG38|POTEI_HUMAN,sp|P0CG39|POTEJ_HUMAN,tr|A0A804GS07|A0A804GS07_HUMAN,tr|I3L3I0|I3L3I0_HUMAN,tr|G5E9R0|G5E9R0_HUMAN,tr|E7EVS6|E7EVS6_HUMAN,tr|A0A6Q8PFE4|A0A6Q8PFE4_HUMAN,tr|J3KT65|J3KT65_HUMAN,tr|I3L3R2|I3L3R2_HUMAN,tr|K7EM38|K7EM38_HUMAN,tr|A0A6Q8PH58|A0A6Q8PH58_HUMAN,tr|I3L1U9|I3L1U9_HUMAN,tr|A0A804HKV3|A0A804HKV3_HUMAN,tr|A0A2R8Y793|A0A2R8Y793_HUMAN,tr|I3L4N8|I3L4N8_HUMAN,tr|C9JUM1|C9JUM1_HUMAN,tr|C9JZR7|C9JZR7_HUMAN,tr|A0A2R8YGF8|A0A2R8YGF8_HUMAN,tr|A6NL76|A6NL76_HUMAN" 26 1524.7502 0.93 66349 14647 2 1524.75112 763.3824 POTE ankyrin domain family member E OS=Homo sapiens OX=9606 GN=POTEE PE=2 SV=3 6.92 2655.5 - 397822 - - - 0.6349 - 2.108 0.495 - 337 1 2 0 0.001 11 0 0 0 5.81E+06 6.27E+06 - - - 4.7142 0.9916 221125_WJC_METTL3_EV_vs_WT_F05.14648.14648.3 4.88E-05 Oct-52 R.ELKEVFGDDSEISK.E sp|O43395|PRPF3_HUMAN 1 1594.7726 2.11 66350 14648 3 1594.771107 532.5982 U4\U6 small nuclear ribonucleoprotein Prp3 OS=Homo sapiens OX=9606 GN=PRPF3 PE=1 SV=2 4.18 2655.7 - 392525 - - - -0.9569 - 1.783 0.252 - 77.7 1 2 1 -0.0015 14 0 0 0 3.03E+07 1.43E+07 - - - 2.886 0.9997 221125_WJC_METTL3_EV_vs_WT_F05.14649.14649.3 0.0213 Dec-48 R.KIQVEYGVTGSFK.D sp|O00443|P3C2A_HUMAN 1 1454.7769 0.54 66351 14649 3 1454.776631 485.9329 Phosphatidylinositol 4-phosphate 3-kinase C2 domain-containing subunit alpha OS=Homo sapiens OX=9606 GN=PIK3C2A PE=1 SV=2 8.5 2655.8 - 359929 - - - -0.2055 - 2.337 0.296 - 165 1 2 0 -0.0003 13 0 0 0 2.96E+06 5.48E+06 - - - 4.1416 0.9996 221125_WJC_METTL3_EV_vs_WT_F05.14650.14650.2 2.42E-06 20-Aug K.IWHHTFYNELR.V "sp|Q6S8J3|POTEE_HUMAN,sp|P63261|ACTG_HUMAN,sp|P68133|ACTS_HUMAN,sp|Q9BYX7|ACTBM_HUMAN,sp|P68032|ACTC_HUMAN,sp|P60709|ACTB_HUMAN,sp|A5A3E0|POTEF_HUMAN,sp|P0CG38|POTEI_HUMAN,sp|P0CG39|POTEJ_HUMAN,tr|A0A804GS07|A0A804GS07_HUMAN,tr|I3L3I0|I3L3I0_HUMAN,tr|G5E9R0|G5E9R0_HUMAN,tr|E7EVS6|E7EVS6_HUMAN,tr|A0A6Q8PFE4|A0A6Q8PFE4_HUMAN,tr|J3KT65|J3KT65_HUMAN,tr|I3L3R2|I3L3R2_HUMAN,tr|K7EM38|K7EM38_HUMAN,tr|A0A6Q8PH58|A0A6Q8PH58_HUMAN,tr|I3L1U9|I3L1U9_HUMAN,tr|A0A804HKV3|A0A804HKV3_HUMAN,tr|A0A2R8Y793|A0A2R8Y793_HUMAN,tr|I3L4N8|I3L4N8_HUMAN,tr|C9JUM1|C9JUM1_HUMAN,tr|C9JZR7|C9JZR7_HUMAN,tr|A0A2R8YGF8|A0A2R8YGF8_HUMAN,tr|A6NL76|A6NL76_HUMAN" 26 1514.7419 0.93 66352 14650 2 1514.739003 758.3782 POTE ankyrin domain family member E OS=Homo sapiens OX=9606 GN=POTEE PE=2 SV=3 6.92 2655.9 - 322935 - - - -1.9007 - 2.022 0.449 - 218.8 1 2 0 -0.0029 11 0 0 0 5.81E+06 6.27E+06 - - - 4.2611 1 221125_WJC_METTL3_EV_vs_WT_F05.14655.14655.2 8.21E-08 Nov-36 K.LPGQDESTAGTSEQNDILK[136.11].V "sp|Q9Y520|PRC2C_HUMAN,tr|E7EPN9|E7EPN9_HUMAN" 2 2009.9633 1.38 66357 14655 2 2009.961386 1005.9889 Protein PRRC2C OS=Homo sapiens OX=9606 GN=PRRC2C PE=1 SV=4 3.92 2656.6 - 170218 - - - -0.9493 - 2.572 0.626 - 182.9 1 2 0 -0.0019 19 0 0 0 2.31E+06 1.68E+06 - - - 5.9866 1 221125_WJC_METTL3_EV_vs_WT_F05.14657.14657.2 5.94E-06 22-Dec R.AQVQEFC[160.03]DYGTK[136.11].E "sp|Q86U44|MTA70_HUMAN,tr|H0YFV6|H0YFV6_HUMAN" 2 1452.6435 0.001 66358 14657 2 1452.644619 727.329 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 4.37 2656.8 - 332877 - - - 0.7841 - 2.698 0.593 - 407.2 1 2 0 0.0011 12 0 0 0 0.00E+00 6.56E+06 - - - 6.032 1 221125_WJC_METTL3_EV_vs_WT_F05.14660.14660.2 6.49E-08 13/22 K.TEELEEESFPER.S "sp|Q9Y2W1|TR150_HUMAN,tr|A0A3B3ITZ9|A0A3B3ITZ9_HUMAN" 2 1493.6522 2.54 66360 14660 2 1493.652676 747.8334 Thyroid hormone receptor-associated protein 3 OS=Homo sapiens OX=9606 GN=THRAP3 PE=1 SV=2 3.9 2657.1 - 2.56E+06 - - - 0.3301 - 2.644 0.677 - 716.9 1 2 0 0.0005 12 0 0 0 3.25E+07 1.28E+07 - - - 6.5994 0.9999 221125_WJC_METTL3_EV_vs_WT_F05.14663.14663.3 0.000383 14/56 R.DVVIC[160.03]PDASLEDAK[136.11]K[136.11].E "sp|Q99497|PARK7_HUMAN,tr|K7EN27|K7EN27_HUMAN,tr|K7ELW0|K7ELW0_HUMAN" 3 1674.8469 2.68 66363 14663 3 1674.852475 559.2896 Parkinson disease protein 7 OS=Homo sapiens OX=9606 GN=PARK7 PE=1 SV=2 4.23 2657.3 - 1.76E+06 - - - 3.3066 - 2.904 0.5 - 186.5 1 2 0 0.0055 15 0 0 0 4.46E+08 1.67E+08 - - - 6.8948 1 221125_WJC_METTL3_EV_vs_WT_F05.14664.14664.3 3.08E-05 15/52 K.K[136.11]VYENYPTYDLTER[166.11].K "sp|P35659|DEK_HUMAN,tr|H0Y993|H0Y993_HUMAN,tr|A0A494C028|A0A494C028_HUMAN,tr|A0A494C198|A0A494C198_HUMAN,tr|B4DFG0|B4DFG0_HUMAN" 5 1807.8747 0.82 66364 14664 3 1807.876968 603.6322 Protein DEK OS=Homo sapiens OX=9606 GN=DEK PE=1 SV=1 4.68 2657.3 - 1.49E+06 - - - 1.2269 - 2.661 0.576 - 282.5 1 2 0 0.0022 14 0 0 0 9.68E+06 1.19E+07 - - - 7.5621 1 221125_WJC_METTL3_EV_vs_WT_F05.14665.14665.3 3.54E-06 16/36 K.TQHLQELFSR[166.11].L "sp|Q9UHI6|DDX20_HUMAN,tr|A0A7P0T8G7|A0A7P0T8G7_HUMAN,tr|A0A7P0TB94|A0A7P0TB94_HUMAN,tr|A0A7P0T9T8|A0A7P0T9T8_HUMAN" 4 1267.6549 0.98 66365 14665 3 1267.654753 423.5589 Probable ATP-dependent RNA helicase DDX20 OS=Homo sapiens OX=9606 GN=DDX20 PE=1 SV=2 6.41 2657.4 - 1.07E+06 - - - -0.0805 - 2.693 0.487 - 501.3 1 2 0 -0.0001 10 0 0 0 9.54E+06 9.74E+06 - - - 6.8627 1 221125_WJC_METTL3_EV_vs_WT_F05.14666.14666.3 1.43E-06 16/36 K.TQHLQELFSR.L "sp|Q9UHI6|DDX20_HUMAN,tr|A0A7P0T8G7|A0A7P0T8G7_HUMAN,tr|A0A7P0TB94|A0A7P0TB94_HUMAN,tr|A0A7P0T9T8|A0A7P0T9T8_HUMAN" 4 1257.6466 0.98 66366 14666 3 1257.645913 420.2228 Probable ATP-dependent RNA helicase DDX20 OS=Homo sapiens OX=9606 GN=DDX20 PE=1 SV=2 6.41 2657.5 - 961916 - - - -0.5343 - 3.022 0.539 - 563.7 1 2 0 -0.0007 10 0 0 0 9.54E+06 9.74E+06 - - - 7.7789 0.9998 221125_WJC_METTL3_EV_vs_WT_F05.14668.14668.3 9.89E-09 17/56 K.IANLGSC[160.03]NDSKLEFR.S sp|Q9HCY8|S10AE_HUMAN 1 1722.8359 0.29 66368 14668 3 1722.841092 575.2859 Protein S100-A14 OS=Homo sapiens OX=9606 GN=S100A14 PE=1 SV=1 6.06 2657.8 - 808078 - - - 3.0026 - 3.716 0.571 - 548.1 1 2 1 0.0052 15 0 0 0 7.31E+06 2.49E+07 - - - 8.3298 1 221125_WJC_METTL3_EV_vs_WT_F05.14669.14669.3 6.43E-10 15/56 K.KIFVGGLSPDTPEEK.L "sp|Q14103|HNRPD_HUMAN,tr|H0Y8G5|H0Y8G5_HUMAN,tr|D6RF44|D6RF44_HUMAN,tr|D6RAF8|D6RAF8_HUMAN,tr|H0YA96|H0YA96_HUMAN" 5 1615.8457 1.08 66369 14669 3 1615.847286 539.6225 Heterogeneous nuclear ribonucleoprotein D0 OS=Homo sapiens OX=9606 GN=HNRNPD PE=1 SV=1 4.68 2657.9 - 797714 - - - 0.958 - 2.863 0.575 - 349.1 1 2 0 0.0015 15 0 0 0 6.09E+06 5.65E+06 - - - 7.695 0.9997 221125_WJC_METTL3_EV_vs_WT_F05.14670.14670.3 0.000711 Nov-36 R.R[166.11]IDISPSTFR[166.11].K "sp|Q9Y2W1|TR150_HUMAN,tr|A0A3B3ITZ9|A0A3B3ITZ9_HUMAN" 2 1210.6573 2.42 66370 14670 3 1210.658275 404.5597 Thyroid hormone receptor-associated protein 3 OS=Homo sapiens OX=9606 GN=THRAP3 PE=1 SV=2 9.6 2658 - 656988 - - - 0.7963 - 2.487 0.27 - 224.9 1 2 0 0.001 10 0 0 0 2.39E+07 9.87E+06 - - - 4.2107 1 221125_WJC_METTL3_EV_vs_WT_F05.14674.14674.3 6.52E-05 Dec-36 R.ETC[160.03]VDLHLPR.F "sp|P48594|SPB4_HUMAN,tr|H0Y5H9|H0Y5H9_HUMAN" 2 1238.6078 74.58 66374 14674 3 1238.606707 413.8765 Serpin B4 OS=Homo sapiens OX=9606 GN=SERPINB4 PE=1 SV=2 5.32 2658.5 - 438973 - - - -0.8477 - 2.269 0.548 - 241.8 1 2 0 -0.001 10 0 0 0 6.76E+06 9.06E+04 - - - 7.0422 0.9995 221125_WJC_METTL3_EV_vs_WT_F05.14675.14675.2 9.44E-05 13/20 K.HFSGLEEAVYR[166.11].N "sp|P50990|TCPQ_HUMAN,tr|H7C4C8|H7C4C8_HUMAN" 2 1316.6389 0.44 66375 14675 2 1316.635708 659.3267 T-complex protein 1 subunit theta OS=Homo sapiens OX=9606 GN=CCT8 PE=1 SV=4 5.4 2658.6 - 425306 - - - -2.4016 - 2.04 0.461 - 457.4 1 2 0 -0.0032 11 0 0 0 3.36E+06 7.63E+06 - - - 4.3737 0.9998 221125_WJC_METTL3_EV_vs_WT_F05.14677.14677.2 0.00348 24-Sep K.KTGQPMINLYTDR.E "sp|P35637|FUS_HUMAN,tr|H3BPE7|H3BPE7_HUMAN" 2 1535.7766 0.96 66377 14677 2 1535.776964 768.8956 RNA-binding protein FUS OS=Homo sapiens OX=9606 GN=FUS PE=1 SV=1 8.59 2658.9 - 421083 - - - 0.2285 - 1.967 0.47 - 166.7 1 2 0 0.0004 13 0 0 0 5.64E+06 5.88E+06 - - - 4.2486 0.9998 221125_WJC_METTL3_EV_vs_WT_F05.14678.14678.2 0.0001 22-Nov K.DKPTETLLNTVK.D sp|Q96SI9|STRBP_HUMAN 1 1357.7453 0.76 66378 14678 2 1357.746921 679.8799 Spermatid perinuclear RNA-binding protein OS=Homo sapiens OX=9606 GN=STRBP PE=1 SV=1 6.07 2659 - 386419 - - - 1.1968 - 2.082 0.498 - 320.7 1 2 0 0.0016 12 0 0 0 3.58E+06 4.73E+06 - - - 4.6482 0.9135 221125_WJC_METTL3_EV_vs_WT_F05.14681.14681.2 1.51 22-May K.DK[136.11]PTETLLNTVK[136.11].D sp|Q96SI9|STRBP_HUMAN 1 1373.7737 0.76 66380 14681 2 1373.775077 687.8941 Spermatid perinuclear RNA-binding protein OS=Homo sapiens OX=9606 GN=STRBP PE=1 SV=1 6.07 2659.4 - 265649 - - - 1.0053 - 0.967 0.115 - 33 9 2 0 0.0014 12 0 0 0 3.58E+06 4.73E+06 - - - -0.6246 1 221125_WJC_METTL3_EV_vs_WT_F05.14682.14682.3 0.127 15/40 K.HFSGLEEAVYR[166.11].N "sp|P50990|TCPQ_HUMAN,tr|H7C4C8|H7C4C8_HUMAN" 2 1316.6389 0.3 66381 14682 3 1316.63938 439.8869 T-complex protein 1 subunit theta OS=Homo sapiens OX=9606 GN=CCT8 PE=1 SV=4 5.4 2659.5 - 1.48E+06 - - - 0.3873 - 2.906 0.429 - 553.7 1 2 0 0.0005 11 0 0 0 4.37E+06 1.47E+07 - - - 6.3533 0.9998 221125_WJC_METTL3_EV_vs_WT_F05.14683.14683.3 0.00131 Nov-40 R.GEEYLSAFDKK.A sp|Q5JSZ5|PRC2B_HUMAN 1 1285.619 1.46 66382 14683 3 1285.618976 429.547 Protein PRRC2B OS=Homo sapiens OX=9606 GN=PRRC2B PE=1 SV=2 4.68 2659.6 - 1.27E+06 - - - -0.0443 - 1.853 0.397 - 201 1 2 0 -0.0001 11 0 0 0 1.23E+07 8.43E+06 - - - 4.7184 0.9998 221125_WJC_METTL3_EV_vs_WT_F05.14684.14684.3 1.26E-06 13/52 R.ELK[136.11]EVFGDDSEISK[136.11].E sp|O43395|PRPF3_HUMAN 1 1610.801 2.04 66383 14684 3 1610.800665 537.941 U4\U6 small nuclear ribonucleoprotein Prp3 OS=Homo sapiens OX=9606 GN=PRPF3 PE=1 SV=2 4.18 2659.7 - 1.24E+06 - - - -0.2285 - 2.194 0.478 - 153.9 1 2 1 -0.0004 14 0 0 0 3.01E+07 1.47E+07 - - - 5.9572 0.9999 221125_WJC_METTL3_EV_vs_WT_F05.14685.14685.3 9.90E-05 13/64 K.SNMGHPEPASGLAALAK.V "sp|P49327|FAS_HUMAN,tr|A0A0U1RQF0|A0A0U1RQF0_HUMAN" 2 1649.8195 0.97 66384 14685 3 1649.816775 550.9471 Fatty acid synthase OS=Homo sapiens OX=9606 GN=FASN PE=1 SV=3 6.47 2659.8 - 811649 - - - -1.6759 - 2.48 0.388 - 113.9 1 2 0 -0.0028 17 0 0 0 1.67E+07 1.73E+07 - - - 5.1596 0.9774 221125_WJC_METTL3_EV_vs_WT_F05.14686.14686.3 0.231 Sep-40 R.ERPAAIPIEIK.S sp|Q9Y2H1|ST38L_HUMAN 1 1235.7238 3.63 66385 14686 3 1235.723602 412.9152 Serine\threonine-protein kinase 38-like OS=Homo sapiens OX=9606 GN=STK38L PE=1 SV=3 6.24 2659.9 - 466038 - - - -0.1376 - 1.635 0.124 - 108.1 1 2 0 -0.0002 11 0 0 0 3.55E+06 9.76E+05 - - - 1.3191 0.9998 221125_WJC_METTL3_EV_vs_WT_F05.14689.14689.2 6.88E-06 14/28 R.DVVIC[160.03]PDASLEDAKK.E "sp|Q99497|PARK7_HUMAN,tr|K7EN27|K7EN27_HUMAN,tr|K7ELW0|K7ELW0_HUMAN" 3 1658.8185 4.4 66388 14689 2 1658.815721 830.4165 Parkinson disease protein 7 OS=Homo sapiens OX=9606 GN=PARK7 PE=1 SV=2 4.23 2660.3 - 284998 - - - -1.6976 - 2.574 0.55 - 527.4 1 2 0 -0.0028 15 0 0 0 1.89E+07 4.29E+06 - - - 5.4269 1 221125_WJC_METTL3_EV_vs_WT_F05.14691.14691.2 1.64E-08 14/36 K.LPGQDESTAGTSEQNDILK.V "sp|Q9Y520|PRC2C_HUMAN,tr|E7EPN9|E7EPN9_HUMAN" 2 2001.9491 1.38 66390 14691 2 2001.950651 1001.9818 Protein PRRC2C OS=Homo sapiens OX=9606 GN=PRRC2C PE=1 SV=4 3.92 2660.5 - 220738 - - - 0.7777 - 3.064 0.674 - 486.1 1 2 0 0.0016 19 0 0 0 2.31E+06 1.68E+06 - - - 6.7716 0.9996 221125_WJC_METTL3_EV_vs_WT_F05.14693.14693.2 0.000908 26-Jul K.ELSTTLNADEAVTR[166.11].G "sp|P34932|HSP74_HUMAN,tr|A0A087WTS8|A0A087WTS8_HUMAN,tr|A0A087WYC1|A0A087WYC1_HUMAN" 3 1528.7608 1.41 66392 14693 2 1528.75887 765.3877 Heat shock 70 kDa protein 4 OS=Homo sapiens OX=9606 GN=HSPA4 PE=1 SV=4 4.14 2660.8 - 140841 - - - -1.286 - 1.681 0.435 - 150.3 1 2 0 -0.002 14 0 0 0 1.52E+06 1.08E+06 - - - 3.5567 0.9999 221125_WJC_METTL3_EV_vs_WT_F05.14696.14696.3 1.67E-06 Dec-48 R.FTENDKEYQEYLK.R "sp|Q9BTL3|RAMAC_HUMAN,tr|A0A3B3IU46|A0A3B3IU46_HUMAN" 2 1705.7835 1.21 66393 14696 3 1705.782567 569.6018 RNA guanine-N7 methyltransferase activating subunit OS=Homo sapiens OX=9606 GN=RAMAC PE=1 SV=1 4.41 2661.2 - 1.40E+06 - - - -0.5657 - 2.881 0.575 - 94.1 1 2 1 -0.001 13 0 0 0 2.99E+07 2.46E+07 - - - 7.8193 1 221125_WJC_METTL3_EV_vs_WT_F05.14697.14697.3 3.46E-05 Dec-40 R.GEEYLSAFDK[136.11]K[136.11].A sp|Q5JSZ5|PRC2B_HUMAN 1 1301.6474 1.52 66394 14697 3 1301.647452 434.8898 Protein PRRC2B OS=Homo sapiens OX=9606 GN=PRRC2B PE=1 SV=2 4.68 2661.3 - 1.05E+06 - - - 0.0146 - 2.077 0.494 - 210.8 1 2 0 0 11 0 0 0 1.25E+07 8.17E+06 - - - 6.124 0.9999 221125_WJC_METTL3_EV_vs_WT_F05.14699.14699.3 3.56E-05 19/52 R.QAMLENASDIK[136.11]LEK[136.11].F "sp|Q8NE71|ABCF1_HUMAN,tr|Q5STZ8|Q5STZ8_HUMAN,tr|A0A0G2JJB9|A0A0G2JJB9_HUMAN,tr|H0YGW7|H0YGW7_HUMAN" 4 1604.8415 1.22 66396 14699 3 1604.843715 535.9544 ATP-binding cassette sub-family F member 1 OS=Homo sapiens OX=9606 GN=ABCF1 PE=1 SV=2 4.68 2661.5 - 1.92E+06 - - - 1.4064 - 3.297 0.528 - 523.3 1 2 1 0.0023 14 0 0 0 1.96E+07 1.60E+07 - - - 7.5965 0.9999 221125_WJC_METTL3_EV_vs_WT_F05.14701.14701.3 0.000116 Nov-40 K.HFSGLEEAVYR.N "sp|P50990|TCPQ_HUMAN,tr|H7C4C8|H7C4C8_HUMAN" 2 1306.6306 0.3 66398 14701 3 1306.628628 436.5508 T-complex protein 1 subunit theta OS=Homo sapiens OX=9606 GN=CCT8 PE=1 SV=4 5.4 2661.7 - 606756 - - - -1.5092 - 2.522 0.438 - 274.2 1 2 0 -0.002 11 0 0 0 4.37E+06 1.44E+07 - - - 6.0506 0.9997 221125_WJC_METTL3_EV_vs_WT_F05.14702.14702.3 0.0331 Dec-56 K.ITSYFLNEGSQARPR.S sp|O75792|RNH2A_HUMAN 1 1737.8798 1.82 66399 14702 3 1737.879407 580.3006 Ribonuclease H2 subunit A OS=Homo sapiens OX=9606 GN=RNASEH2A PE=1 SV=2 8.75 2661.9 - 468439 - - - -0.2446 - 2.478 0.306 - 262.1 1 2 0 -0.0004 15 0 0 0 4.55E+07 2.50E+07 - - - 4.3194 0.9961 221125_WJC_METTL3_EV_vs_WT_F05.14703.14703.3 0.0337 Nov-40 K.YDVQHLQTALR.N "sp|O14653|GOSR2_HUMAN,tr|I3NI02|I3NI02_HUMAN,tr|E7EQ34|E7EQ34_HUMAN,tr|A0A1W2PPP5|A0A1W2PPP5_HUMAN,tr|A0A1W2PPG5|A0A1W2PPG5_HUMAN,tr|I3L0K1|I3L0K1_HUMAN,tr|A0A1W2PR23|A0A1W2PR23_HUMAN,tr|A0A1W2PRC2|A0A1W2PRC2_HUMAN,tr|A0A1W2PQP2|A0A1W2PQP2_HUMAN,tr|A0A1W2PRP7|A0A1W2PRP7_HUMAN,tr|A0A1W2PR02|A0A1W2PR02_HUMAN,tr|A0A1X7SBU8|A0A1X7SBU8_HUMAN,tr|A0A1W2PS81|A0A1W2PS81_HUMAN,tr|I3L4Z6|I3L4Z6_HUMAN,tr|A0A1W2PQ77|A0A1W2PQ77_HUMAN,tr|A0A1W2PPJ0|A0A1W2PPJ0_HUMAN,tr|A0A1W2PRD0|A0A1W2PRD0_HUMAN,tr|A0A1W2PPG1|A0A1W2PPG1_HUMAN,tr|A0A1W2PRV0|A0A1W2PRV0_HUMAN,tr|A0A1W2PQ06|A0A1W2PQ06_HUMAN,tr|A0A1W2PPW8|A0A1W2PPW8_HUMAN,tr|A0A1W2PNV3|A0A1W2PNV3_HUMAN,tr|A0A1W2PQ38|A0A1W2PQ38_HUMAN,tr|A0A1W2PQM3|A0A1W2PQM3_HUMAN,tr|A0A1W2PRE6|A0A1W2PRE6_HUMAN,tr|A0A1W2PQE0|A0A1W2PQE0_HUMAN,tr|I3L1K7|I3L1K7_HUMAN,tr|A0A1W2PS12|A0A1W2PS12_HUMAN,tr|A0A1W2PRL0|A0A1W2PRL0_HUMAN" 29 1342.6993 1.51 66400 14703 3 1342.703223 448.5737 Golgi SNAP receptor complex member 2 OS=Homo sapiens OX=9606 GN=GOSR2 PE=1 SV=2 6.74 2662 - 462856 - - - 2.8852 - 1.783 0.275 - 126 1 2 0 0.0039 11 0 0 0 4.94E+06 3.27E+06 - - - 3.2477 0.9999 221125_WJC_METTL3_EV_vs_WT_F05.14711.14711.3 9.39E-05 Sep-52 K.AQLHDTNMELTDLK[136.11].L "sp|O14974|MYPT1_HUMAN,tr|H0YIM2|H0YIM2_HUMAN,tr|H0YIS3|H0YIS3_HUMAN,tr|A0A0U1RQZ1|A0A0U1RQZ1_HUMAN" 4 1635.8018 0.77 66406 14711 3 1635.801418 546.2745 Protein phosphatase 1 regulatory subunit 12A OS=Homo sapiens OX=9606 GN=PPP1R12A PE=1 SV=1 4.54 2663 - 697650 - - - -0.2158 - 2.001 0.43 - 98.8 1 2 0 -0.0004 14 0 0 0 4.80E+06 6.27E+06 - - - 5.1774 0.9976 221125_WJC_METTL3_EV_vs_WT_F05.14714.14714.3 0.078 14/48 R.ISLGMPVGPNAHK[136.11].V "sp|Q13435|SF3B2_HUMAN,tr|E9PPJ0|E9PPJ0_HUMAN,tr|H0YEX5|H0YEX5_HUMAN" 3 1327.7162 4.5 66409 14714 3 1327.712399 443.5793 Splicing factor 3B subunit 2 OS=Homo sapiens OX=9606 GN=SF3B2 PE=1 SV=2 8.76 2663.4 - 548421 - - - -2.856 - 2.194 0.26 - 141.4 1 2 0 -0.0038 13 0 0 0 2.66E+07 5.91E+06 - - - 3.568 0.9998 221125_WJC_METTL3_EV_vs_WT_F05.14716.14716.3 0.00211 Nov-40 R.HNLSLNDC[160.03]FVK[136.11].V "sp|Q12952|FOXL1_HUMAN,sp|Q9NU39|FX4L1_HUMAN,sp|Q6VB84|FX4L3_HUMAN,sp|Q8WXT5|FX4L4_HUMAN,sp|Q9UJU5|FOXD3_HUMAN,sp|Q12950|FOXD4_HUMAN,sp|Q9C009|FOXQ1_HUMAN,sp|Q16676|FOXD1_HUMAN,sp|O60548|FOXD2_HUMAN,sp|Q5VV16|FX4L5_HUMAN,sp|Q3SYB3|FX4L6_HUMAN,tr|M0R279|M0R279_HUMAN" 12 1353.6591 0.83 66411 14716 3 1353.656332 452.227 Forkhead box protein L1 OS=Homo sapiens OX=9606 GN=FOXL1 PE=2 SV=2 6.73 2663.7 - 455768 - - - -2.0227 - 1.81 0.42 - 130.9 1 2 0 -0.0027 11 0 0 0 2.85E+06 3.41E+06 - - - 4.9074 0.936 221125_WJC_METTL3_EV_vs_WT_F05.14721.14721.3 0.000253 Nov-40 K.TRLEQEIATYR.R "sp|Q04695|K1C17_HUMAN,sp|P02533|K1C14_HUMAN,sp|P35900|K1C20_HUMAN,sp|P08779|K1C16_HUMAN,sp|P19012|K1C15_HUMAN,sp|P13646|K1C13_HUMAN,tr|A0A3B3IS58|A0A3B3IS58_HUMAN,tr|F5GWP8|F5GWP8_HUMAN,tr|K7ERE3|K7ERE3_HUMAN,tr|A8MT21|A8MT21_HUMAN" 10 1378.7205 13.26 66416 14721 3 1379.727328 460.5808 "Keratin, type I cytoskeletal 17 OS=Homo sapiens OX=9606 GN=KRT17 PE=1 SV=2" 5.81 2664.3 - 301948 - - - 730.2786 - 2.145 0.377 - 264.8 1 2 1 1.0069 11 0 0 0 3.33E+06 2.51E+05 - - - 4.6322 0.9995 221125_WJC_METTL3_EV_vs_WT_F05.14722.14722.2 4.82E-05 28-Dec R.DVVIC[160.03]PDASLEDAK[136.11]K[136.11].E "sp|Q99497|PARK7_HUMAN,tr|K7EN27|K7EN27_HUMAN,tr|K7ELW0|K7ELW0_HUMAN" 3 1674.8469 4.4 66417 14722 2 1674.84296 838.4307 Parkinson disease protein 7 OS=Homo sapiens OX=9606 GN=PARK7 PE=1 SV=2 4.23 2664.5 - 274494 - - - -2.3745 - 2.383 0.428 - 358.5 1 2 0 -0.004 15 0 0 0 1.89E+07 4.29E+06 - - - 4.3359 1 221125_WJC_METTL3_EV_vs_WT_F05.14725.14725.2 4.76E-14 20/38 R.FSSC[160.03]GGGGGSFGAGGGFGSR.S sp|P04264|K2C1_HUMAN 1 1764.7274 999 66420 14725 2 1764.724227 883.371 "Keratin, type II cytoskeletal 1 OS=Homo sapiens OX=9606 GN=KRT1 PE=1 SV=6" 8.25 2664.9 - 284727 - - - -1.8156 - 4.109 0.77 - 1290.4 1 2 0 -0.0032 20 0 0 0 6.77E+08 0.00E+00 - - - 8.2016 0.9822 221125_WJC_METTL3_EV_vs_WT_F05.14726.14726.2 6.09E-05 20-Sep K.HFSGLEEAVYR.N "sp|P50990|TCPQ_HUMAN,tr|H7C4C8|H7C4C8_HUMAN" 2 1306.6306 0.47 66421 14726 2 1306.625407 654.3226 T-complex protein 1 subunit theta OS=Homo sapiens OX=9606 GN=CCT8 PE=1 SV=4 5.4 2665 - 192684 - - - -3.9743 - 1.721 0.175 - 220.4 1 2 0 -0.0052 11 0 0 0 3.61E+06 7.63E+06 - - - 1.8006 0.9999 221125_WJC_METTL3_EV_vs_WT_F05.14727.14727.3 0.00319 Dec-44 K.SLIEEGGDWDR[166.11]R[166.11].N "sp|Q15008|PSMD6_HUMAN,tr|C9J0E9|C9J0E9_HUMAN,tr|H7C531|H7C531_HUMAN" 3 1451.6908 0.45 66422 14727 3 1451.692753 484.9042 26S proteasome non-ATPase regulatory subunit 6 OS=Homo sapiens OX=9606 GN=PSMD6 PE=1 SV=1 4.32 2665.1 - 182524 - - - 1.3481 - 2.251 0.387 - 189 1 2 0 0.002 12 0 0 0 2.69E+06 5.91E+06 - - - 5.1031 0.9999 221125_WJC_METTL3_EV_vs_WT_F05.14733.14733.3 0.00139 15/52 K.SQIHDIVLVGGSTR[166.11].L "sp|P11142|HSP7C_HUMAN,tr|E9PNE6|E9PNE6_HUMAN,tr|A8K7Q2|A8K7Q2_HUMAN,tr|E9PKE3|E9PKE3_HUMAN,tr|E9PN89|E9PN89_HUMAN" 5 1490.8081 0.45 66426 14733 3 1490.810787 497.9433 Heat shock cognate 71 kDa protein OS=Homo sapiens OX=9606 GN=HSPA8 PE=1 SV=1 6.46 2665.9 - 1.62E+06 - - - 1.8285 - 3.009 0.428 - 266.1 1 2 0 0.0027 14 0 0 0 1.28E+07 2.84E+07 - - - 6.2386 0.9997 221125_WJC_METTL3_EV_vs_WT_F05.14734.14734.3 0.0315 Jul-48 K.DFVDLSTGEDAHK[136.11].L "sp|O75794|CD123_HUMAN,tr|X6RA30|X6RA30_HUMAN" 2 1440.6612 1.2 66427 14734 3 1440.661523 481.2277 Cell division cycle protein 123 homolog OS=Homo sapiens OX=9606 GN=CDC123 PE=1 SV=1 4.22 2665.9 - 980337 - - - 0.1978 - 1.595 0.405 - 36.7 1 2 0 0.0003 13 0 0 0 1.40E+07 1.16E+07 - - - 4.3211 0.9987 221125_WJC_METTL3_EV_vs_WT_F05.14735.14735.3 0.0107 Nov-48 K.DFVDLSTGEDAHK.L "sp|O75794|CD123_HUMAN,tr|X6RA30|X6RA30_HUMAN" 2 1432.647 1.19 66428 14735 3 1432.643546 478.5563 Cell division cycle protein 123 homolog OS=Homo sapiens OX=9606 GN=CDC123 PE=1 SV=1 4.22 2666 - 972595 - - - -2.4374 - 1.767 0.334 - 121.2 1 2 0 -0.0035 13 0 0 0 1.40E+07 1.18E+07 - - - 3.8063 0.9999 221125_WJC_METTL3_EV_vs_WT_F05.14737.14737.2 2.00E-06 26-Nov K.HYGPGWVSMANAGK[136.11].D "sp|P23284|PPIB_HUMAN,tr|A0A7P0Z497|A0A7P0Z497_HUMAN,tr|A0A7P0TB45|A0A7P0TB45_HUMAN" 3 1481.6965 0.19 66430 14737 2 1481.696275 741.8555 Peptidyl-prolyl cis-trans isomerase B OS=Homo sapiens OX=9606 GN=PPIB PE=1 SV=2 8.6 2666.3 - 514356 - - - -0.164 - 2.16 0.568 - 289.7 1 2 0 -0.0002 14 0 0 0 1.94E+06 9.97E+06 - - - 5.1687 1 221125_WJC_METTL3_EV_vs_WT_F05.14743.14743.3 8.16E-07 14/48 K.K[136.11]TGQPMINLYTDR[166.11].E "sp|P35637|FUS_HUMAN,tr|H3BPE7|H3BPE7_HUMAN" 2 1553.7991 1.16 66435 14743 3 1553.799642 518.9403 RNA-binding protein FUS OS=Homo sapiens OX=9606 GN=FUS PE=1 SV=1 8.59 2667 - 5.16E+06 - - - 0.3598 - 3.171 0.568 - 367.2 1 2 0 0.0006 13 0 0 0 1.70E+08 1.46E+08 - - - 8.0014 1 221125_WJC_METTL3_EV_vs_WT_F05.14746.14746.3 3.18E-06 13/76 R.FSSC[160.03]GGGGGSFGAGGGFGSR.S sp|P04264|K2C1_HUMAN 1 1764.7274 999 66437 14746 3 1764.72672 589.2498 "Keratin, type II cytoskeletal 1 OS=Homo sapiens OX=9606 GN=KRT1 PE=1 SV=6" 8.25 2667.3 - 4.24E+06 - - - -0.4029 - 2.369 0.64 - 140 1 2 0 -0.0007 20 0 0 0 2.24E+08 0.00E+00 - - - 7.7675 0.9995 221125_WJC_METTL3_EV_vs_WT_F05.14748.14748.3 0.0248 Aug-52 R.DFTVSAMHGDMDQK[136.11].E "sp|P60842|IF4A1_HUMAN,tr|J3QL52|J3QL52_HUMAN,tr|J3KT12|J3KT12_HUMAN,tr|J3KSZ0|J3KSZ0_HUMAN" 4 1588.6741 0.92 66439 14748 3 1588.675937 530.5653 Eukaryotic initiation factor 4A-I OS=Homo sapiens OX=9606 GN=EIF4A1 PE=1 SV=1 4.41 2667.4 - 1.69E+06 - - - 1.1387 - 1.508 0.384 - 42.8 1 2 0 0.0018 14 0 0 0 1.38E+07 1.49E+07 - - - 3.9124 0.9999 221125_WJC_METTL3_EV_vs_WT_F05.14749.14749.3 2.44E-06 Nov-56 K.NK[136.11]QPVTDPLLTPVEK[136.11].A "sp|Q9BVJ6|UT14A_HUMAN,tr|X6RJY0|X6RJY0_HUMAN" 2 1693.9585 2.03 66440 14749 3 1693.958314 565.6601 U3 small nucleolar RNA-associated protein 14 homolog A OS=Homo sapiens OX=9606 GN=UTP14A PE=1 SV=1 6.07 2667.5 - 1.34E+06 - - - -0.1316 - 2.458 0.517 - 172.7 1 2 1 -0.0002 15 0 0 0 3.75E+07 1.85E+07 - - - 6.6507 1 221125_WJC_METTL3_EV_vs_WT_F05.14750.14750.3 1.80E-08 17/60 R.IAEFTTNLTEEEEK[136.11]SK[136.11].S sp|P35579|MYH9_HUMAN 1 1883.9335 0.94 66441 14750 3 1883.934117 628.9851 Myosin-9 OS=Homo sapiens OX=9606 GN=MYH9 PE=1 SV=4 4.33 2667.6 - 1.05E+06 - - - 0.3254 - 3.467 0.61 - 414.6 1 2 1 0.0006 16 0 0 0 2.76E+07 2.95E+07 - - - 8.5308 1 221125_WJC_METTL3_EV_vs_WT_F05.14752.14752.3 2.16E-06 13/60 K.INEELESQYQQSMDSK[136.11].L "sp|O00193|SMAP_HUMAN,tr|E9PM92|E9PM92_HUMAN,tr|E9PRZ9|E9PRZ9_HUMAN" 3 1935.8611 0.37 66443 14752 3 1935.858652 646.2943 Small acidic protein OS=Homo sapiens OX=9606 GN=SMAP PE=1 SV=1 4 2667.9 - 378544 - - - -1.2837 - 2.603 0.557 - 226 1 2 0 -0.0025 16 0 0 0 2.81E+06 7.53E+06 - - - 7.204 1 221125_WJC_METTL3_EV_vs_WT_F05.14754.14754.2 7.02E-09 15/30 K.INEELESQYQQSMDSK[136.11].L "sp|O00193|SMAP_HUMAN,tr|E9PM92|E9PM92_HUMAN,tr|E9PRZ9|E9PRZ9_HUMAN" 3 1935.8611 0.29 66445 14754 2 1935.86643 968.9378 Small acidic protein OS=Homo sapiens OX=9606 GN=SMAP PE=1 SV=1 4 2668.1 - 325565 - - - 2.7342 - 3.572 0.628 - 990.6 1 2 0 0.0053 16 0 0 0 2.32E+06 7.98E+06 - - - 6.8078 1 221125_WJC_METTL3_EV_vs_WT_F05.14759.14759.3 1.17E-09 16/52 K.HYGPGWVSMANAGK[136.11].D "sp|P23284|PPIB_HUMAN,tr|A0A7P0Z497|A0A7P0Z497_HUMAN,tr|A0A7P0TB45|A0A7P0TB45_HUMAN" 3 1481.6965 0.4 66449 14759 3 1481.69754 494.9061 Peptidyl-prolyl cis-trans isomerase B OS=Homo sapiens OX=9606 GN=PPIB PE=1 SV=2 8.6 2668.7 - 3.23E+06 - - - 0.6897 - 2.696 0.463 - 415.2 1 2 0 0.001 14 0 0 0 1.96E+07 4.95E+07 - - - 6.3374 0.9996 221125_WJC_METTL3_EV_vs_WT_F05.14761.14761.3 0.00387 Dec-32 K.R[166.11]FDLQQLQR[166.11].E "sp|Q13948|CASP_HUMAN,tr|A0A2R8Y852|A0A2R8Y852_HUMAN,tr|A0A2R8YDI1|A0A2R8YDI1_HUMAN" 3 1222.6685 1.05 66450 14761 3 1222.667949 408.5635 Protein CASP OS=Homo sapiens OX=9606 GN=CUX1 PE=1 SV=2 9.6 2668.9 - 1.74E+06 - - - -0.4866 - 2.236 0.272 - 327.3 1 2 0 -0.0006 9 0 0 0 5.64E+07 5.38E+07 - - - 3.9975 0.9999 221125_WJC_METTL3_EV_vs_WT_F05.14763.14763.3 1.48E-05 Dec-56 K.ITSYFLNEGSQAR[166.11]PR[166.11].S sp|O75792|RNH2A_HUMAN 1 1757.8964 31.44 66452 14763 3 1757.897446 586.9727 Ribonuclease H2 subunit A OS=Homo sapiens OX=9606 GN=RNASEH2A PE=1 SV=2 8.75 2669.1 - 2.53E+06 - - - 0.611 - 2.285 0.422 - 220 1 2 0 0.0011 15 0 0 0 8.03E+08 2.55E+07 - - - 5.4009 1 221125_WJC_METTL3_EV_vs_WT_F05.14764.14764.3 3.07E-08 16/52 K.HYGPGWVSMANAGK.D "sp|P23284|PPIB_HUMAN,tr|A0A7P0Z497|A0A7P0Z497_HUMAN,tr|A0A7P0TB45|A0A7P0TB45_HUMAN" 3 1473.6823 0.39 66453 14764 3 1473.683852 492.2347 Peptidyl-prolyl cis-trans isomerase B OS=Homo sapiens OX=9606 GN=PPIB PE=1 SV=2 8.6 2669.1 - 1.68E+06 - - - 1.0409 - 3.134 0.616 - 427.9 1 2 0 0.0015 14 0 0 0 2.01E+07 5.18E+07 - - - 8.4431 0.9998 221125_WJC_METTL3_EV_vs_WT_F05.14765.14765.3 0.00464 Nov-32 K.RFDLQQLQR.E "sp|Q13948|CASP_HUMAN,tr|A0A2R8Y852|A0A2R8Y852_HUMAN,tr|A0A2R8YDI1|A0A2R8YDI1_HUMAN" 3 1202.652 1 66454 14765 3 1202.651592 401.8913 Protein CASP OS=Homo sapiens OX=9606 GN=CUX1 PE=1 SV=2 9.6 2669.2 - 1.23E+06 - - - -0.3426 - 2.127 0.325 - 237.3 1 2 0 -0.0004 9 0 0 0 5.66E+07 5.69E+07 - - - 4.4379 0.9999 221125_WJC_METTL3_EV_vs_WT_F05.14766.14766.3 0.000237 15/44 R.QTVQVIQQALHR.Q "sp|Q8IXK0|PHC2_HUMAN,tr|A0A0A0MSI2|A0A0A0MSI2_HUMAN" 2 1419.7946 2.12 66455 14766 3 1419.794854 474.2722 Polyhomeotic-like protein 2 OS=Homo sapiens OX=9606 GN=PHC2 PE=1 SV=1 9.76 2669.3 - 1.02E+06 - - - 0.1465 - 2.571 0.383 - 425.1 1 2 0 0.0002 12 0 0 0 4.39E+07 2.07E+07 - - - 5.4275 0.9999 221125_WJC_METTL3_EV_vs_WT_F05.14767.14767.3 2.90E-06 14/48 R.NK[136.11]QEVMISDLEER[166.11].L sp|P35580|MYH10_HUMAN 1 1607.7944 0.44 66456 14767 3 1607.795693 536.9387 Myosin-10 OS=Homo sapiens OX=9606 GN=MYH10 PE=1 SV=3 4.41 2669.4 - 812548 - - - 0.8098 - 2.728 0.474 - 391.1 1 2 1 0.0013 13 0 0 0 8.70E+06 1.97E+07 - - - 6.5452 0.9875 221125_WJC_METTL3_EV_vs_WT_F05.14768.14768.3 0.012 Sep-36 K.DK[136.11]VNC[160.03]SFYFK[136.11].L "sp|Q01081|U2AF1_HUMAN,sp|Q8WU68|U2AF4_HUMAN,tr|M0R2N4|M0R2N4_HUMAN,tr|A0A1B0GW87|A0A1B0GW87_HUMAN,tr|M0QYK5|M0QYK5_HUMAN" 5 1322.63 0.83 66457 14768 3 1322.628538 441.8839 Splicing factor U2AF 35 kDa subunit OS=Homo sapiens OX=9606 GN=U2AF1 PE=1 SV=3 8.18 2669.5 - 672017 - - - -1.1122 - 1.414 0.278 - 129.9 1 2 1 -0.0015 10 0 0 0 6.14E+06 7.40E+06 - - - 2.6507 0.9988 221125_WJC_METTL3_EV_vs_WT_F05.14771.14771.3 0.0013 Aug-48 R.KAVEAAQLAEDLK.V "sp|O75150|BRE1B_HUMAN,tr|H3BP71|H3BP71_HUMAN,tr|A0A087WTK2|A0A087WTK2_HUMAN" 3 1384.7562 1.15 66460 14771 3 1384.755045 462.5927 E3 ubiquitin-protein ligase BRE1B OS=Homo sapiens OX=9606 GN=RNF40 PE=1 SV=5 4.68 2669.9 - 316018 - - - -0.8305 - 1.543 0.313 - 63.4 1 2 0 -0.0011 13 0 0 0 2.68E+06 2.32E+06 - - - 3.2053 0.9938 221125_WJC_METTL3_EV_vs_WT_F05.14775.14775.2 1.79E-06 Nov-32 S.TASAVPELATDPELEK[136.11]K[136.11].L "sp|Q86U44|MTA70_HUMAN,tr|B4E349|B4E349_HUMAN,tr|F5H6D8|F5H6D8_HUMAN,tr|H0YFV6|H0YFV6_HUMAN,tr|B4DTN4|B4DTN4_HUMAN" 5 1813.9644 0.001 66464 14775 2 1813.964464 907.9895 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 4.41 2670.4 - 139386 - - - 0.0298 - 2.245 0.556 - 216.7 1 1 0 0.0001 17 0 0 0 0.00E+00 3.25E+07 - - - 5.1358 0.9999 221125_WJC_METTL3_EV_vs_WT_F05.14779.14779.3 0.000417 Nov-52 R.DFTVSAMHGDMDQK.E "sp|P60842|IF4A1_HUMAN,tr|J3QL52|J3QL52_HUMAN,tr|J3KT12|J3KT12_HUMAN,tr|J3KSZ0|J3KSZ0_HUMAN" 4 1580.6599 0.92 66466 14779 3 1580.661052 527.8939 Eukaryotic initiation factor 4A-I OS=Homo sapiens OX=9606 GN=EIF4A1 PE=1 SV=1 4.41 2671 - 984970 - - - 0.7111 - 1.902 0.477 - 100.2 1 2 0 0.0011 14 0 0 0 1.38E+07 1.49E+07 - - - 5.5663 0.9998 221125_WJC_METTL3_EV_vs_WT_F05.14781.14781.2 0.00272 16-Sep R.DYQELMNTK.L sp|P04264|K2C1_HUMAN 1 1140.5121 26.6 66468 14781 2 1140.513301 571.2633 "Keratin, type II cytoskeletal 1 OS=Homo sapiens OX=9606 GN=KRT1 PE=1 SV=6" 4.37 2671.1 - 4.28E+06 - - - 1.0311 - 1.938 0.481 - 240.2 1 2 0 0.0012 9 0 0 0 4.91E+07 1.85E+06 - - - 4.5075 0.9996 221125_WJC_METTL3_EV_vs_WT_F05.14783.14783.2 0.00636 14/16 K.R[166.11]FDLQQLQR[166.11].E "sp|Q13948|CASP_HUMAN,tr|A0A2R8Y852|A0A2R8Y852_HUMAN,tr|A0A2R8YDI1|A0A2R8YDI1_HUMAN" 3 1222.6685 1.27 66470 14783 2 1222.671587 612.3415 Protein CASP OS=Homo sapiens OX=9606 GN=CUX1 PE=1 SV=2 9.6 2671.3 - 1.68E+06 - - - 2.4888 - 2.695 0.366 - 469.7 1 2 0 0.003 9 0 0 0 2.88E+07 2.27E+07 - - - 4.6115 1 221125_WJC_METTL3_EV_vs_WT_F05.14784.14784.3 3.27E-06 14/44 R.QTVQVIQQALHR[166.11].Q "sp|Q8IXK0|PHC2_HUMAN,tr|A0A0A0MSI2|A0A0A0MSI2_HUMAN" 2 1429.8029 2.14 66471 14784 3 1429.803605 477.6082 Polyhomeotic-like protein 2 OS=Homo sapiens OX=9606 GN=PHC2 PE=1 SV=1 9.76 2671.4 - 1.27E+06 - - - 0.4819 - 2.665 0.481 - 441.6 1 2 0 0.0007 12 0 0 0 4.36E+07 2.04E+07 - - - 6.6195 1 221125_WJC_METTL3_EV_vs_WT_F05.14787.14787.2 1.08E-08 30-Nov K.INEELESQYQQSMDSK.L "sp|O00193|SMAP_HUMAN,tr|E9PM92|E9PM92_HUMAN,tr|E9PRZ9|E9PRZ9_HUMAN" 3 1927.8469 0.29 66474 14787 2 1927.847411 964.9307 Small acidic protein OS=Homo sapiens OX=9606 GN=SMAP PE=1 SV=1 4 2671.8 - 241239 - - - 0.2459 - 2.738 0.703 - 446 1 2 0 0.0005 16 0 0 0 2.32E+06 7.98E+06 - - - 6.7095 0.9974 221125_WJC_METTL3_EV_vs_WT_F05.14788.14788.3 0.0538 Aug-40 K.NVDDILK[136.11]PPGR[166.11].E "sp|P49750|YLPM1_HUMAN,tr|H0YIQ2|H0YIQ2_HUMAN,tr|F8VU51|F8VU51_HUMAN,tr|H0YI23|H0YI23_HUMAN" 4 1240.6895 13.5 66475 14788 3 1240.689411 414.5704 YLP motif-containing protein 1 OS=Homo sapiens OX=9606 GN=YLPM1 PE=1 SV=4 5.96 2671.9 - 217703 - - - -0.0363 - 1.427 0.279 - 72.9 1 2 0 0 11 0 0 0 4.83E+07 3.58E+06 - - - 2.6607 0.9996 221125_WJC_METTL3_EV_vs_WT_F05.14793.14793.3 2.68E-05 Dec-48 R.NKQEVMISDLEER.L sp|P35580|MYH10_HUMAN 1 1589.7719 0.49 66478 14793 3 1589.770211 530.9313 Myosin-10 OS=Homo sapiens OX=9606 GN=MYH10 PE=1 SV=3 4.41 2672.6 - 570188 - - - -1.0756 - 2.51 0.4 - 220 1 2 1 -0.0017 13 0 0 0 8.70E+06 1.77E+07 - - - 5.4943 0.9998 221125_WJC_METTL3_EV_vs_WT_F05.14796.14796.2 0.0091 24-Nov K.SQTINNEAFSGIK.L sp|Q9H7E2|TDRD3_HUMAN 1 1407.6994 1.03 66481 14796 2 1407.701837 704.857 Tudor domain-containing protein 3 OS=Homo sapiens OX=9606 GN=TDRD3 PE=1 SV=1 5.72 2672.9 - 260004 - - - 1.7255 - 2.521 0.536 - 422.9 1 2 0 0.0024 13 0 0 0 7.17E+06 6.99E+06 - - - 5.3723 0.9996 221125_WJC_METTL3_EV_vs_WT_F05.14797.14797.2 4.96E-07 24-Sep R.FSGSGSGTDFTLK.L "sp|A2NJV5|KV229_HUMAN,sp|A0A087WW87|KV240_HUMAN,sp|P06310|KV230_HUMAN,sp|A0A075B6S2|KVD29_HUMAN,sp|P01614|KVD40_HUMAN,sp|P01615|KVD28_HUMAN,sp|A0A075B6S6|KVD30_HUMAN,sp|A0A075B6P5|KV228_HUMAN,sp|A0A0A0MRZ7|KVD26_HUMAN" 9 1302.6092 999 66482 14797 2 1302.605696 652.3119 Immunoglobulin kappa variable 2-29 OS=Homo sapiens OX=9606 GN=IGKV2-29 PE=3 SV=2 5.84 2673 - 258021 - - - -2.6869 - 1.945 0.588 - 117.3 1 2 0 -0.0035 13 0 0 0 7.05E+06 0.00E+00 - - - 5.0903 1 221125_WJC_METTL3_EV_vs_WT_F05.14802.14802.3 2.17E-05 Dec-64 K.SAADAEGYLAHPVNAYK.L "sp|O15460|P4HA2_HUMAN,tr|C9JCP0|C9JCP0_HUMAN,tr|E7ERI1|E7ERI1_HUMAN,tr|E7EPI9|E7EPI9_HUMAN,tr|C9JN43|C9JN43_HUMAN,tr|E7ENX0|E7ENX0_HUMAN,tr|C9JX45|C9JX45_HUMAN,tr|A8MXE0|A8MXE0_HUMAN,tr|C9JIG4|C9JIG4_HUMAN" 9 1775.8479 2.51 66485 14802 3 1775.849254 592.9566 Prolyl 4-hydroxylase subunit alpha-2 OS=Homo sapiens OX=9606 GN=P4HA2 PE=1 SV=1 5.3 2673.5 - 1.36E+06 - - - 0.7833 - 2.175 0.503 - 119.9 1 2 0 0.0014 17 0 0 0 3.70E+07 1.48E+07 - - - 6.1106 1 221125_WJC_METTL3_EV_vs_WT_F05.14804.14804.2 5.68E-11 18/32 R.QQEESFQEQSALAAEAR.E "sp|Q9BSV6|SEN34_HUMAN,tr|A0A590UJ73|A0A590UJ73_HUMAN,tr|E7EQB3|E7EQB3_HUMAN,tr|A0A0G2JNK5|A0A0G2JNK5_HUMAN,tr|A0A0G2JNL0|A0A0G2JNL0_HUMAN,tr|A0A590UJW4|A0A590UJW4_HUMAN,tr|B0V3J0|B0V3J0_HUMAN" 7 1920.8813 2.97 66487 14804 2 1920.883249 961.448 tRNA-splicing endonuclease subunit Sen34 OS=Homo sapiens OX=9606 GN=TSEN34 PE=1 SV=1 4.09 2673.8 - 471321 - - - 0.9891 - 3.64 0.72 - 1474.8 1 2 0 0.0019 17 0 0 0 7.59E+06 2.55E+06 - - - 7.5347 0.914 221125_WJC_METTL3_EV_vs_WT_F05.14805.14805.3 0.0362 13/40 E.SLKEELAYLKK.N sp|P02533|K1C14_HUMAN 1 1320.7653 22.25 66488 14805 3 1320.763848 441.2624 "Keratin, type I cytoskeletal 14 OS=Homo sapiens OX=9606 GN=KRT14 PE=1 SV=4" 8.16 2673.9 - 366567 - - - -1.1016 - 2.309 0.333 - 176.5 1 1 1 -0.0015 11 0 0 0 7.05E+06 3.17E+05 - - - 4.6295 0.9999 221125_WJC_METTL3_EV_vs_WT_F05.14811.14811.2 2.44E-05 13/30 K.GGK[136.11]PEPPAMPQPVPTA.- "sp|P23396|RS3_HUMAN,tr|H0YEU2|H0YEU2_HUMAN,tr|E9PL09|E9PL09_HUMAN,tr|E9PPU1|E9PPU1_HUMAN" 4 1580.8112 0.86 66493 14811 2 1580.811345 791.4129 40S ribosomal protein S3 OS=Homo sapiens OX=9606 GN=RPS3 PE=1 SV=2 6 2674.6 - 853767 - - - 0.0829 - 2.269 0.575 - 253.4 1 2 0 0.0001 16 0 0 0 1.70E+08 1.98E+08 - - - 5.3023 0.9982 221125_WJC_METTL3_EV_vs_WT_F05.14814.14814.3 0.0109 Oct-48 R.QIGVEHVVVYVNK.A sp|P49411|EFTU_HUMAN 1 1482.8195 7.29 66495 14814 3 1482.818782 495.2804 "Elongation factor Tu, mitochondrial OS=Homo sapiens OX=9606 GN=TUFM PE=1 SV=2" 6.75 2674.9 - 1.18E+06 - - - -0.4599 - 1.654 0.268 - 138.2 1 2 0 -0.0007 13 0 0 0 1.20E+07 1.65E+06 - - - 2.8921 0.9997 221125_WJC_METTL3_EV_vs_WT_F05.14815.14815.3 0.00109 Oct-52 K.YIYDSAFHPDTGEK[136.11].M "sp|Q9H9B4|SFXN1_HUMAN,tr|D6RFI0|D6RFI0_HUMAN,tr|D6RDG7|D6RDG7_HUMAN,tr|S4R2X2|S4R2X2_HUMAN" 4 1649.7453 0.76 66496 14815 3 1649.747931 550.9224 Sideroflexin-1 OS=Homo sapiens OX=9606 GN=SFXN1 PE=1 SV=4 4.54 2675 - 562883 - - - 1.5936 - 1.705 0.403 - 61.1 1 2 0 0.0026 14 0 0 0 2.06E+07 2.71E+07 - - - 4.4503 1 221125_WJC_METTL3_EV_vs_WT_F05.14817.14817.2 2.20E-08 14/28 A.SAVPELATDPELEK[136.11]K[136.11].L "sp|Q86U44|MTA70_HUMAN,tr|B4E349|B4E349_HUMAN,tr|F5H6D8|F5H6D8_HUMAN,tr|H0YFV6|H0YFV6_HUMAN,tr|B4DTN4|B4DTN4_HUMAN" 5 1641.8796 0.01 66498 14817 2 1641.886178 821.9471 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 4.41 2675.3 - 163244 - - - 3.9954 - 2.619 0.613 - 561.1 1 1 0 0.0066 15 0 0 0 7.29E+04 5.62E+06 - - - 5.9336 0.9997 221125_WJC_METTL3_EV_vs_WT_F05.14822.14822.3 1.66E-07 18/64 R.QQEESFQEQSALAAEAR.E "sp|Q9BSV6|SEN34_HUMAN,tr|A0A590UJ73|A0A590UJ73_HUMAN,tr|E7EQB3|E7EQB3_HUMAN,tr|A0A0G2JNK5|A0A0G2JNK5_HUMAN,tr|A0A0G2JNL0|A0A0G2JNL0_HUMAN,tr|A0A590UJW4|A0A590UJW4_HUMAN,tr|B0V3J0|B0V3J0_HUMAN" 7 1920.8813 2.65 66501 14822 3 1920.87077 641.3011 tRNA-splicing endonuclease subunit Sen34 OS=Homo sapiens OX=9606 GN=TSEN34 PE=1 SV=1 4.09 2676 - 982945 - - - -5.5074 - 2.951 0.579 - 572.7 1 2 0 -0.0106 17 0 0 0 1.15E+07 4.32E+06 - - - 7.7262 0.9999 221125_WJC_METTL3_EV_vs_WT_F05.14826.14826.3 4.15E-05 Dec-52 K.YIYDSAFHPDTGEK.M "sp|Q9H9B4|SFXN1_HUMAN,tr|D6RFI0|D6RFI0_HUMAN,tr|D6RDG7|D6RDG7_HUMAN,tr|S4R2X2|S4R2X2_HUMAN" 4 1641.7311 0.75 66505 14826 3 1641.734767 548.251 Sideroflexin-1 OS=Homo sapiens OX=9606 GN=SFXN1 PE=1 SV=4 4.54 2676.4 - 598043 - - - 2.2324 - 2.114 0.493 - 73.1 1 2 0 0.0037 14 0 0 0 2.04E+07 2.73E+07 - - - 6.0248 0.7628 221125_WJC_METTL3_EV_vs_WT_F05.14828.14828.3 0.000219 13/52 M.PDSWDKDVYPEPPR.R "sp|O96000|NDUBA_HUMAN,tr|H3BPJ9|H3BPJ9_HUMAN,tr|H3BV16|H3BV16_HUMAN" 3 1699.7842 2.82 66507 14828 3 1699.778432 567.602 NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 10 OS=Homo sapiens OX=9606 GN=NDUFB10 PE=1 SV=3 4.23 2676.7 - 436188 - - - -3.394 - 2.215 0.088 - 209 1 2 1 -0.0058 14 0 0 0 4.56E+07 1.62E+07 - - - 1.6329 1 221125_WJC_METTL3_EV_vs_WT_F05.14832.14832.2 1.44E-07 13/24 R.C[160.03]QVFEETQIGGER[166.11].Y sp|Q99832|TCPH_HUMAN 1 1561.707 0.04 66511 14832 2 1561.712299 781.8608 T-complex protein 1 subunit eta OS=Homo sapiens OX=9606 GN=CCT7 PE=1 SV=2 4.25 2677.2 - 200822 - - - 3.3758 - 2.506 0.599 - 611 1 2 0 0.0053 13 0 0 0 1.15E+06 3.03E+07 - - - 5.8214 1 221125_WJC_METTL3_EV_vs_WT_F05.14835.14835.2 2.36E-05 17/22 V.PELATDPELEK[136.11]K[136.11].L "sp|Q86U44|MTA70_HUMAN,tr|B4E349|B4E349_HUMAN,tr|F5H6D8|F5H6D8_HUMAN,tr|H0YFV6|H0YFV6_HUMAN,tr|B4DTN4|B4DTN4_HUMAN" 5 1384.7421 0.95 66514 14835 2 1384.737549 693.3783 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 4.41 2677.6 - 140170 - - - -3.2584 - 3.207 0.511 - 962.1 1 1 0 -0.0045 12 0 0 0 3.08E+06 3.24E+06 - - - 5.88 0.9997 221125_WJC_METTL3_EV_vs_WT_F05.14838.14838.2 0.000524 30-Jul K.GGKPEPPAMPQPVPTA.- "sp|P23396|RS3_HUMAN,tr|H0YEU2|H0YEU2_HUMAN,tr|E9PL09|E9PL09_HUMAN,tr|E9PPU1|E9PPU1_HUMAN" 4 1572.797 0.86 66516 14838 2 1572.796338 787.4058 40S ribosomal protein S3 OS=Homo sapiens OX=9606 GN=RPS3 PE=1 SV=2 6 2677.9 - 255595 - - - -0.4298 - 1.395 0.498 - 76.9 1 2 0 -0.0007 16 0 0 0 1.70E+08 1.99E+08 - - - 3.5375 0.9999 221125_WJC_METTL3_EV_vs_WT_F05.14840.14840.3 1.75E-05 14/36 K.QNR[166.11]PIPQWIR[166.11].M "sp|P62891|RL39_HUMAN,sp|Q59GN2|R39L5_HUMAN" 2 1326.7424 0.73 66517 14840 3 1326.742594 443.2547 60S ribosomal protein L39 OS=Homo sapiens OX=9606 GN=RPL39 PE=1 SV=2 12 2678.2 - 2.62E+06 - - - 0.1628 - 2.335 0.398 - 463.6 1 2 0 0.0002 10 0 0 0 5.35E+08 7.31E+08 - - - 5.4538 1 221125_WJC_METTL3_EV_vs_WT_F05.14841.14841.3 1.51E-07 14/52 R.NLDIERPTYTNLNR.L "sp|Q9NY65|TBA8_HUMAN,sp|Q6PEY2|TBA3E_HUMAN,sp|P0DPH7|TBA3C_HUMAN,sp|Q71U36|TBA1A_HUMAN,sp|P0DPH8|TBA3D_HUMAN,sp|Q9H853|TBA4B_HUMAN,sp|P68366|TBA4A_HUMAN,sp|P68363|TBA1B_HUMAN,sp|Q9BQE3|TBA1C_HUMAN,tr|F8VVB9|F8VVB9_HUMAN,tr|C9JDS9|C9JDS9_HUMAN,tr|A0A7P0TA31|A0A7P0TA31_HUMAN,tr|F5H5D3|F5H5D3_HUMAN,tr|C9J2C0|C9J2C0_HUMAN,tr|F8VQQ4|F8VQQ4_HUMAN,tr|A0A7P0T945|A0A7P0T945_HUMAN" 16 1717.8747 0.6 66518 14841 3 1717.879245 573.6322 Tubulin alpha-8 chain OS=Homo sapiens OX=9606 GN=TUBA8 PE=1 SV=1 6.07 2678.2 - 1.74E+06 - - - 2.6184 - 2.649 0.573 - 254.7 1 2 0 0.0045 14 0 0 0 5.17E+08 8.59E+08 - - - 7.5161 0.9999 221125_WJC_METTL3_EV_vs_WT_F05.14842.14842.3 4.88E-07 18/48 K.LQQESTFLFHGNK.T sp|Q9UKX7|NUP50_HUMAN 1 1547.7732 1.26 66519 14842 3 1547.767193 516.9317 Nuclear pore complex protein Nup50 OS=Homo sapiens OX=9606 GN=NUP50 PE=1 SV=2 6.75 2678.3 - 1.35E+06 - - - -3.9082 - 3.184 0.569 - 509 1 2 0 -0.006 13 0 0 0 3.79E+07 3.01E+07 - - - 8.0222 1 221125_WJC_METTL3_EV_vs_WT_F05.14843.14843.3 4.32E-09 15/56 R.VYNVTQHAVGIVVNK.Q "sp|P46778|RL21_HUMAN,tr|G3V1B3|G3V1B3_HUMAN,tr|M0R181|M0R181_HUMAN" 3 1639.9046 1.14 66520 14843 3 1639.905193 547.6421 60S ribosomal protein L21 OS=Homo sapiens OX=9606 GN=RPL21 PE=1 SV=2 8.57 2678.4 - 1.24E+06 - - - 0.3677 - 2.587 0.585 - 113.7 1 2 0 0.0006 15 0 0 0 1.08E+08 9.45E+07 - - - 7.5422 0.9999 221125_WJC_METTL3_EV_vs_WT_F05.14844.14844.3 0.000449 15/36 K.QNRPIPQWIR.M "sp|P62891|RL39_HUMAN,sp|Q59GN2|R39L5_HUMAN" 2 1306.7258 0.73 66521 14844 3 1306.72612 436.5826 60S ribosomal protein L39 OS=Homo sapiens OX=9606 GN=RPL39 PE=1 SV=2 12 2678.4 - 1.15E+06 - - - 0.2158 - 2.444 0.408 - 484.8 1 2 0 0.0003 10 0 0 0 5.36E+08 7.33E+08 - - - 5.6985 0.9998 221125_WJC_METTL3_EV_vs_WT_F05.14846.14846.3 1.26E-06 14/60 R.LQEGDKILSVNGQDLK.N "sp|P57105|SYJ2B_HUMAN,tr|A0A087X1F5|A0A087X1F5_HUMAN,tr|A0A087WYV9|A0A087WYV9_HUMAN" 3 1755.9367 2.32 66523 14846 3 1755.935978 586.3195 Synaptojanin-2-binding protein OS=Homo sapiens OX=9606 GN=SYNJ2BP PE=1 SV=2 4.56 2678.7 - 787520 - - - -0.3992 - 2.552 0.48 - 255 1 2 1 -0.0007 16 0 0 0 8.03E+06 3.45E+06 - - - 6.2952 0.9991 221125_WJC_METTL3_EV_vs_WT_F05.14847.14847.3 0.0163 Aug-48 R.EKPSQGIYMVYC[160.03]R.K "sp|Q8IWS0|PHF6_HUMAN,tr|Q5JRC6|Q5JRC6_HUMAN,tr|A0A0D9SGE8|A0A0D9SGE8_HUMAN" 3 1629.7643 0.38 66524 14847 3 1629.765136 544.2621 PHD finger protein 6 OS=Homo sapiens OX=9606 GN=PHF6 PE=1 SV=1 8.27 2678.7 - 705805 - - - 0.4921 - 1.55 0.325 - 80.5 1 2 0 0.0008 13 0 0 0 1.18E+07 3.07E+07 - - - 3.3514 0.9977 221125_WJC_METTL3_EV_vs_WT_F05.14848.14848.3 0.000297 13/56 R.TEMEDLMSSKDDVGK.S sp|P35579|MYH9_HUMAN 1 1683.7332 1.39 66525 14848 3 1683.74233 562.2517 Myosin-9 OS=Homo sapiens OX=9606 GN=MYH9 PE=1 SV=4 4.1 2678.9 - 487581 - - - 5.4504 - 2.246 0.562 - 134.5 1 2 1 0.0092 15 0 0 0 5.08E+06 3.65E+06 - - - 6.9146 1 221125_WJC_METTL3_EV_vs_WT_F05.14854.14854.3 2.33E-07 14/56 R.VYNVTQHAVGIVVNK[136.11].Q "sp|P46778|RL21_HUMAN,tr|G3V1B3|G3V1B3_HUMAN,tr|M0R181|M0R181_HUMAN" 3 1647.9188 1.14 66529 14854 3 1647.917958 550.3135 60S ribosomal protein L21 OS=Homo sapiens OX=9606 GN=RPL21 PE=1 SV=2 8.57 2679.6 - 3.32E+06 - - - -0.5049 - 2.533 0.497 - 110.8 1 2 0 -0.0008 15 0 0 0 1.07E+08 9.42E+07 - - - 6.506 0.9896 221125_WJC_METTL3_EV_vs_WT_F05.14861.14861.3 0.00797 Oct-48 K.EKDQLSQSIVMYK.S "sp|A6NHR9|SMHD1_HUMAN,tr|J3KTL8|J3KTL8_HUMAN" 2 1567.7916 0.77 66536 14861 3 1567.788736 523.6045 Structural maintenance of chromosomes flexible hinge domain-containing protein 1 OS=Homo sapiens OX=9606 GN=SMCHD1 PE=1 SV=2 6.17 2680.3 - 524539 - - - -1.8229 - 1.886 0.251 - 158.7 1 2 1 -0.0029 13 0 0 0 7.54E+06 9.75E+06 - - - 3.0578 0.9857 221125_WJC_METTL3_EV_vs_WT_F05.14865.14865.2 0.00347 26-Aug K.THMVVANTMEDFQK.L sp|P07814|SYEP_HUMAN 1 1649.7542 1.08 66540 14865 2 1649.744504 825.8844 Bifunctional glutamate\proline--tRNA ligase OS=Homo sapiens OX=9606 GN=EPRS1 PE=1 SV=5 5.29 2680.8 - 318403 - - - -5.8548 - 1.649 0.396 - 146 1 2 0 -0.0097 14 0 0 0 1.84E+06 1.70E+06 - - - 3.218 0.9988 221125_WJC_METTL3_EV_vs_WT_F05.14868.14868.2 0.0554 18-Aug K.QNRPIPQWIR.M "sp|P62891|RL39_HUMAN,sp|Q59GN2|R39L5_HUMAN" 2 1306.7258 0.82 66543 14868 2 1306.72538 654.3702 60S ribosomal protein L39 OS=Homo sapiens OX=9606 GN=RPL39 PE=1 SV=2 12 2681.2 - 246834 - - - -0.3505 - 1.73 0.218 - 86.8 1 2 0 -0.0005 10 0 0 0 4.23E+07 5.19E+07 - - - 2.181 0.9995 221125_WJC_METTL3_EV_vs_WT_F05.14869.14869.2 0.0408 26-Sep R.NLDIER[166.11]PTYTNLNR[166.11].L "sp|Q9NY65|TBA8_HUMAN,sp|Q6PEY2|TBA3E_HUMAN,sp|P0DPH7|TBA3C_HUMAN,sp|Q71U36|TBA1A_HUMAN,sp|P0DPH8|TBA3D_HUMAN,sp|Q9H853|TBA4B_HUMAN,sp|P68366|TBA4A_HUMAN,sp|P68363|TBA1B_HUMAN,sp|Q9BQE3|TBA1C_HUMAN,tr|F8VVB9|F8VVB9_HUMAN,tr|C9JDS9|C9JDS9_HUMAN,tr|A0A7P0TA31|A0A7P0TA31_HUMAN,tr|F5H5D3|F5H5D3_HUMAN,tr|C9J2C0|C9J2C0_HUMAN,tr|F8VQQ4|F8VQQ4_HUMAN,tr|A0A7P0T945|A0A7P0T945_HUMAN" 16 1737.8913 0.54 66544 14869 2 1737.891643 869.9529 Tubulin alpha-8 chain OS=Homo sapiens OX=9606 GN=TUBA8 PE=1 SV=1 6.07 2681.3 - 236548 - - - 0.2048 - 1.725 0.356 - 73.6 1 2 0 0.0004 14 0 0 0 2.09E+07 3.90E+07 - - - 3.0385 0.9597 221125_WJC_METTL3_EV_vs_WT_F05.14872.14872.2 0.00125 22-Jul K.DHTPSQELALTQ.S "sp|Q86U44|MTA70_HUMAN,tr|H0YFV6|H0YFV6_HUMAN" 2 1338.6416 - 66546 14872 2 1338.639215 670.3281 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 4.35 2681.8 - 232649 - - - -1.751 - 1.497 0.433 - 174.9 1 1 0 -0.0023 12 0 0 0 - - - - - 3.3 0.9959 221125_WJC_METTL3_EV_vs_WT_F05.14877.14877.3 3.09E-06 13/44 L.RMSVEADINGLR.R "sp|P02533|K1C14_HUMAN,sp|P08727|K1C19_HUMAN,tr|C9JM50|C9JM50_HUMAN" 3 1359.6929 40.62 66550 14877 3 1359.692057 454.2382 "Keratin, type I cytoskeletal 14 OS=Homo sapiens OX=9606 GN=KRT14 PE=1 SV=4" 6.07 2682.2 - 1.82E+06 - - - -0.6075 - 2.544 0.453 - 341.5 1 1 0 -0.0008 12 0 0 0 6.93E+07 1.71E+06 - - - 6.1785 1 221125_WJC_METTL3_EV_vs_WT_F05.14878.14878.2 7.08E-08 15/26 K.EDGLAQQQTQLNLR[166.11].S "sp|P49327|FAS_HUMAN,tr|A0A0U1RQF0|A0A0U1RQF0_HUMAN" 2 1622.8252 0.84 66551 14878 2 1622.823015 812.4199 Fatty acid synthase OS=Homo sapiens OX=9606 GN=FASN PE=1 SV=3 4.37 2682.3 - 1.35E+06 - - - -1.3267 - 3.119 0.603 - 974.9 1 2 0 -0.0022 14 0 0 0 1.82E+07 2.17E+07 - - - 6.3486 0.9997 221125_WJC_METTL3_EV_vs_WT_F05.14879.14879.3 0.000113 16/44 K.AENLGEVLR[166.11]GDR[166.11].L "sp|Q92544|TM9S4_HUMAN,tr|A0A0C4DFM1|A0A0C4DFM1_HUMAN" 2 1347.701 0.89 66552 14879 3 1347.701659 450.2409 Transmembrane 9 superfamily member 4 OS=Homo sapiens OX=9606 GN=TM9SF4 PE=1 SV=2 4.68 2682.5 - 824813 - - - 0.5135 - 2.498 0.399 - 479.8 1 2 1 0.0007 12 0 0 0 2.85E+07 3.20E+07 - - - 5.5259 1 221125_WJC_METTL3_EV_vs_WT_F05.14881.14881.3 4.66E-11 18/64 R.IMLFTNEDNPHGNDSAK.A "sp|P12956|XRCC6_HUMAN,tr|B1AHC9|B1AHC9_HUMAN" 2 1901.8578 0.25 66554 14881 3 1901.853781 634.9599 X-ray repair cross-complementing protein 6 OS=Homo sapiens OX=9606 GN=XRCC6 PE=1 SV=2 4.54 2682.7 - 722699 - - - -2.1006 - 3.704 0.604 - 337.4 1 2 0 -0.004 17 0 0 0 9.38E+06 3.73E+07 - - - 8.5809 0.884 221125_WJC_METTL3_EV_vs_WT_F05.14883.14883.3 0.016 Nov-40 R.QTHGILEYYC[160.03]R[166.11].L "sp|Q9UJV9|DDX41_HUMAN,tr|A0A499FJW5|A0A499FJW5_HUMAN,tr|H0Y8L8|H0Y8L8_HUMAN" 3 1448.6746 1 66556 14883 3 1449.68071 483.8988 Probable ATP-dependent RNA helicase DDX41 OS=Homo sapiens OX=9606 GN=DDX41 PE=1 SV=2 6.74 2683 - 629850 - - - 694.501 - 1.808 0.246 - 121.9 1 2 0 1.0061 11 0 0 0 1.24E+07 1.24E+07 - - - 2.6864 0.9994 221125_WJC_METTL3_EV_vs_WT_F05.14884.14884.2 0.00197 26-Nov R.NLDIERPTYTNLNR.L "sp|Q9NY65|TBA8_HUMAN,sp|Q6PEY2|TBA3E_HUMAN,sp|P0DPH7|TBA3C_HUMAN,sp|Q71U36|TBA1A_HUMAN,sp|P0DPH8|TBA3D_HUMAN,sp|Q9H853|TBA4B_HUMAN,sp|P68366|TBA4A_HUMAN,sp|P68363|TBA1B_HUMAN,sp|Q9BQE3|TBA1C_HUMAN,tr|F8VVB9|F8VVB9_HUMAN,tr|C9JDS9|C9JDS9_HUMAN,tr|A0A7P0TA31|A0A7P0TA31_HUMAN,tr|F5H5D3|F5H5D3_HUMAN,tr|C9J2C0|C9J2C0_HUMAN,tr|F8VQQ4|F8VQQ4_HUMAN,tr|A0A7P0T945|A0A7P0T945_HUMAN" 16 1717.8747 0.54 66557 14884 2 1717.874315 859.9446 Tubulin alpha-8 chain OS=Homo sapiens OX=9606 GN=TUBA8 PE=1 SV=1 6.07 2683.1 - 560933 - - - -0.2515 - 1.694 0.345 - 103.9 1 2 0 -0.0004 14 0 0 0 2.09E+07 3.90E+07 - - - 2.9117 1 221125_WJC_METTL3_EV_vs_WT_F05.14885.14885.2 1.25E-13 17/28 R.VYNVTQHAVGIVVNK[136.11].Q "sp|P46778|RL21_HUMAN,tr|G3V1B3|G3V1B3_HUMAN,tr|M0R181|M0R181_HUMAN" 3 1647.9188 0.85 66558 14885 2 1647.918803 824.9667 60S ribosomal protein L21 OS=Homo sapiens OX=9606 GN=RPL21 PE=1 SV=2 8.57 2683.2 - 540304 - - - 0.0079 - 3.698 0.725 - 991.9 1 2 0 0 15 0 0 0 4.79E+06 5.67E+06 - - - 7.6111 0.9993 221125_WJC_METTL3_EV_vs_WT_F05.14886.14886.3 0.00844 Nov-40 K.QIDLSTVDLKK.L sp|P55145|MANF_HUMAN 1 1258.7133 4.44 66559 14886 3 1258.711199 420.5784 Mesencephalic astrocyte-derived neurotrophic factor OS=Homo sapiens OX=9606 GN=MANF PE=1 SV=3 5.96 2683.4 - 454996 - - - -1.6429 - 2.193 0.278 - 186.1 1 2 0 -0.0021 11 0 0 0 4.95E+07 1.11E+07 - - - 3.8697 0.9921 221125_WJC_METTL3_EV_vs_WT_F05.14888.14888.2 0.002 17/22 L.DIER[166.11]PTYTNLNR[166.11].L "sp|Q9NY65|TBA8_HUMAN,sp|Q6PEY2|TBA3E_HUMAN,sp|P0DPH7|TBA3C_HUMAN,sp|Q71U36|TBA1A_HUMAN,sp|P0DPH8|TBA3D_HUMAN,sp|Q9H853|TBA4B_HUMAN,sp|P68366|TBA4A_HUMAN,sp|P68363|TBA1B_HUMAN,sp|Q9BQE3|TBA1C_HUMAN,tr|F8VVB9|F8VVB9_HUMAN,tr|C9JDS9|C9JDS9_HUMAN,tr|A0A7P0TA31|A0A7P0TA31_HUMAN,tr|F5H5D3|F5H5D3_HUMAN,tr|C9J2C0|C9J2C0_HUMAN,tr|F8VQQ4|F8VQQ4_HUMAN,tr|A0A7P0T945|A0A7P0T945_HUMAN" 16 1510.7643 0.62 66561 14888 2 1510.76424 756.3894 Tubulin alpha-8 chain OS=Homo sapiens OX=9606 GN=TUBA8 PE=1 SV=1 6.07 2683.6 - 298928 - - - -0.0364 - 2.493 0.438 - 386.6 1 1 0 -0.0001 12 0 0 0 4.89E+06 7.89E+06 - - - 4.6796 0.9895 221125_WJC_METTL3_EV_vs_WT_F05.14893.14893.2 4.73E-05 22-Dec L.RMSVEADINGLR.R "sp|P02533|K1C14_HUMAN,sp|P08727|K1C19_HUMAN,tr|C9JM50|C9JM50_HUMAN" 3 1359.6929 0.81 66564 14893 2 1359.692794 680.8537 "Keratin, type I cytoskeletal 14 OS=Homo sapiens OX=9606 GN=KRT14 PE=1 SV=4" 6.07 2684.3 - 686654 - - - -0.0655 - 1.954 0.466 - 196.5 1 1 0 -0.0001 12 0 0 0 1.67E+07 2.05E+07 - - - 4.2454 0.9997 221125_WJC_METTL3_EV_vs_WT_F05.14898.14898.3 0.00761 Dec-40 K.QIDLSTVDLK[136.11]K[136.11].L sp|P55145|MANF_HUMAN 1 1274.7417 1.29 66568 14898 3 1274.740069 425.9212 Mesencephalic astrocyte-derived neurotrophic factor OS=Homo sapiens OX=9606 GN=MANF PE=1 SV=3 5.96 2684.9 - 696906 - - - -1.2536 - 2.058 0.344 - 193.7 1 2 0 -0.0016 11 0 0 0 1.06E+07 8.27E+06 - - - 4.4251 0.9999 221125_WJC_METTL3_EV_vs_WT_F05.14900.14900.2 0.000183 22-Dec K.NVQDAIADAEQR.G sp|P35908|K22E_HUMAN 1 1328.6321 101.54 66569 14900 2 1328.630779 665.3233 "Keratin, type II cytoskeletal 2 epidermal OS=Homo sapiens OX=9606 GN=KRT2 PE=1 SV=2" 4.03 2685.1 - 1.15E+07 - - - -0.9619 - 2.491 0.514 - 512 1 2 0 -0.0013 12 0 0 0 1.23E+09 1.21E+07 - - - 5.2384 0.9804 221125_WJC_METTL3_EV_vs_WT_F05.14902.14902.2 0.000873 15/32 K.VAAPEIVSGVSGESEQK.L sp|O15381|NVL_HUMAN 1 1685.8472 4.55 66571 14902 2 1686.848656 843.9309 Nuclear valosin-containing protein-like OS=Homo sapiens OX=9606 GN=NVL PE=1 SV=1 4.25 2685.3 - 761965 - - - 594.0402 - 2.146 0.365 - 406.5 1 2 0 1.0015 17 0 0 0 2.60E+07 5.72E+06 - - - 3.2998 0.9999 221125_WJC_METTL3_EV_vs_WT_F05.14911.14911.2 4.51E-06 Dec-32 K.VAAPEIVSGVSGESEQK[136.11].L sp|O15381|NVL_HUMAN 1 1693.8614 4.55 66578 14911 2 1693.860798 847.938 Nuclear valosin-containing protein-like OS=Homo sapiens OX=9606 GN=NVL PE=1 SV=1 4.25 2686.4 - 385829 - - - -0.3524 - 2.397 0.531 - 349.6 1 2 0 -0.0006 17 0 0 0 2.60E+07 5.72E+06 - - - 5.1121 1 221125_WJC_METTL3_EV_vs_WT_F05.14926.14926.3 9.09E-07 Nov-48 R.AHLSENELEALEK.N sp|P98175|RBM10_HUMAN 1 1481.7362 0.17 66590 14926 3 1481.736167 494.9193 RNA-binding protein 10 OS=Homo sapiens OX=9606 GN=RBM10 PE=1 SV=3 4.48 2688.2 - 1.17E+06 - - - -0.0142 - 2.454 0.478 - 219.4 1 2 0 0 13 0 0 0 3.53E+07 2.03E+08 - - - 6.3032 0.9999 221125_WJC_METTL3_EV_vs_WT_F05.14928.14928.3 0.00104 21/56 R.WAQEDLLEEQKDGAR.A sp|O75528|TADA3_HUMAN 1 1786.8486 1.46 66592 14928 3 1786.850781 596.6235 Transcriptional adapter 3 OS=Homo sapiens OX=9606 GN=TADA3 PE=1 SV=1 4.18 2688.4 - 828337 - - - 1.2251 - 3.524 0.557 - 614 1 2 1 0.0022 15 0 0 0 7.25E+06 4.95E+06 - - - 8.0361 0.9999 221125_WJC_METTL3_EV_vs_WT_F05.14930.14930.3 3.62E-08 17/56 R.WAQEDLLEEQK[136.11]DGAR[166.11].A sp|O75528|TADA3_HUMAN 1 1804.8711 1.46 66594 14930 3 1804.868392 602.631 Transcriptional adapter 3 OS=Homo sapiens OX=9606 GN=TADA3 PE=1 SV=1 4.18 2688.6 - 589950 - - - -1.4793 - 3.013 0.494 - 209 1 2 1 -0.0027 15 0 0 0 7.25E+06 4.95E+06 - - - 6.9248 0.9997 221125_WJC_METTL3_EV_vs_WT_F05.14935.14935.3 0.0017 Sep-44 K.NVQDAIADAEQR.G sp|P35908|K22E_HUMAN 1 1328.6321 32.85 66597 14935 3 1328.631291 443.8846 "Keratin, type II cytoskeletal 2 epidermal OS=Homo sapiens OX=9606 GN=KRT2 PE=1 SV=2" 4.03 2689.3 - 3.79E+07 - - - -0.5765 - 1.953 0.35 - 187.4 1 2 0 -0.0008 12 0 0 0 4.40E+08 1.34E+07 - - - 4.2973 0.9987 221125_WJC_METTL3_EV_vs_WT_F05.14937.14937.3 3.54E-08 13/48 F.NDTFVHVTDLSGK.E "sp|P62263|RS14_HUMAN,tr|A0A2R8Y811|A0A2R8Y811_HUMAN,tr|E5RH77|E5RH77_HUMAN" 3 1431.6994 1.35 66599 14937 3 1431.698775 478.2404 40S ribosomal protein S14 OS=Homo sapiens OX=9606 GN=RPS14 PE=1 SV=3 5.21 2689.4 - 2.41E+06 - - - -0.4421 - 2.661 0.594 - 340.8 1 1 0 -0.0006 13 0 0 0 1.09E+08 8.08E+07 - - - 7.8159 0.9999 221125_WJC_METTL3_EV_vs_WT_F05.14939.14939.2 3.89E-07 30-Dec K.ASSPSPLTIGTPESQR.K sp|Q9NPI6|DCP1A_HUMAN 1 1626.8213 3.52 66601 14939 2 1626.822625 814.4179 mRNA-decapping enzyme 1A OS=Homo sapiens OX=9606 GN=DCP1A PE=1 SV=3 6.05 2689.6 - 695199 - - - 0.8059 - 2.457 0.553 - 357.7 1 2 0 0.0013 16 0 0 0 1.36E+07 3.86E+06 - - - 5.3351 1 221125_WJC_METTL3_EV_vs_WT_F05.14940.14940.3 3.18E-08 16/44 K.IDEHHFVAVALR[166.11].K "sp|Q9NRN7|ADPPT_HUMAN,tr|E9PLW6|E9PLW6_HUMAN" 2 1415.7549 0.53 66602 14940 3 1415.758231 472.9256 L-aminoadipate-semialdehyde dehydrogenase-phosphopantetheinyl transferase OS=Homo sapiens OX=9606 GN=AASDHPPT PE=1 SV=2 5.99 2689.7 - 624455 - - - 2.3507 - 2.96 0.591 - 479.7 1 2 0 0.0033 12 0 0 0 2.74E+06 5.17E+06 - - - 8.1361 1 221125_WJC_METTL3_EV_vs_WT_F05.14941.14941.3 1.27E-07 15/44 K.NQWQLSADDLK[136.11]K[136.11].L "sp|P09543|CN37_HUMAN,tr|K7ERC4|K7ERC4_HUMAN" 2 1460.7594 1.09 66603 14941 3 1460.758802 487.9271 "2',3'-cyclic-nucleotide 3'-phosphodiesterase OS=Homo sapiens OX=9606 GN=CNP PE=1 SV=2" 5.96 2689.9 - 544634 - - - -0.4388 - 2.873 0.504 - 366.9 1 2 0 -0.0006 12 0 0 0 9.85E+06 9.02E+06 - - - 7.0842 0.9992 221125_WJC_METTL3_EV_vs_WT_F05.14943.14943.3 9.39E-05 Nov-52 R.DAYSGGAVNLYHVR[166.11].E sp|P28074|PSB5_HUMAN 1 1530.7455 0.3 66605 14943 3 1530.740877 511.2558 Proteasome subunit beta type-5 OS=Homo sapiens OX=9606 GN=PSMB5 PE=1 SV=3 6.74 2690.1 - 458693 - - - -2.9946 - 1.847 0.391 - 83.5 1 2 0 -0.0046 14 0 0 0 2.44E+06 8.03E+06 - - - 4.5286 0.9998 221125_WJC_METTL3_EV_vs_WT_F05.14947.14947.2 0.000103 22-Dec R.AQVQEFC[160.03]DYGTK[136.11].E "sp|Q86U44|MTA70_HUMAN,tr|H0YFV6|H0YFV6_HUMAN" 2 1452.6435 0.001 66609 14947 2 1452.640535 727.329 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 4.37 2690.7 - 287203 - - - -2.0273 - 2.587 0.554 - 440.5 1 2 0 -0.0029 12 0 0 0 0.00E+00 6.92E+06 - - - 5.6328 0.9999 221125_WJC_METTL3_EV_vs_WT_F05.14954.14954.2 3.62E-05 13/26 K.STGGAPTFNVTVTK.T "sp|P07737|PROF1_HUMAN,tr|K7EJ44|K7EJ44_HUMAN" 2 1378.7092 1.24 66615 14954 2 1378.70873 690.3619 Profilin-1 OS=Homo sapiens OX=9606 GN=PFN1 PE=1 SV=2 8.47 2691.4 - 1.94E+06 - - - -0.3735 - 2.243 0.482 - 241.8 1 2 0 -0.0005 14 0 0 0 8.64E+07 6.94E+07 - - - 4.6281 0.9982 221125_WJC_METTL3_EV_vs_WT_F05.14955.14955.3 2.01E-06 18/64 S.TASAVPELATDPELEK[136.11]K[136.11].L "sp|Q86U44|MTA70_HUMAN,tr|B4E349|B4E349_HUMAN,tr|F5H6D8|F5H6D8_HUMAN,tr|H0YFV6|H0YFV6_HUMAN,tr|B4DTN4|B4DTN4_HUMAN" 5 1813.9644 0 66616 14955 3 1813.962485 605.6621 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 4.41 2691.5 - 1.46E+06 - - - -1.0612 - 2.994 0.542 - 321.5 1 1 0 -0.0019 17 0 0 0 2.19E+06 1.07E+09 - - - 7.3526 1 221125_WJC_METTL3_EV_vs_WT_F05.14957.14957.3 0.0162 14/44 K.GSGNLEAIHIIK.K "sp|P78371|TCPB_HUMAN,tr|F8VQ14|F8VQ14_HUMAN,tr|F5GWF6|F5GWF6_HUMAN" 3 1250.6983 0.52 66618 14957 3 1250.697794 417.9067 T-complex protein 1 subunit beta OS=Homo sapiens OX=9606 GN=CCT2 PE=1 SV=4 6.75 2691.7 - 1.09E+06 - - - -0.3934 - 2.626 0.443 - 397 1 2 0 -0.0005 12 0 0 0 2.44E+07 4.65E+07 - - - 6.155 0.9977 221125_WJC_METTL3_EV_vs_WT_F05.14958.14958.2 0.0235 18-Dec R.IKFEMEQNLR.Q "sp|P35527|K1C9_HUMAN,tr|K7EQQ3|K7EQQ3_HUMAN" 2 1306.6704 999 66619 14958 2 1306.669736 654.3425 "Keratin, type I cytoskeletal 9 OS=Homo sapiens OX=9606 GN=KRT9 PE=1 SV=3" 6.14 2691.8 - 1.08E+06 - - - -0.4753 - 2.096 0.404 - 382.1 1 2 1 -0.0006 10 0 0 0 2.62E+07 0.00E+00 - - - 4.0904 0.9972 221125_WJC_METTL3_EV_vs_WT_F05.14959.14959.3 0.00457 Dec-36 R.SIHDALC[160.03]VIR[166.11].C "sp|P50991|TCPD_HUMAN,sp|P48643|TCPE_HUMAN,tr|E9PCA1|E9PCA1_HUMAN,tr|B7ZAR1|B7ZAR1_HUMAN,tr|E7ENZ3|E7ENZ3_HUMAN" 5 1192.6262 0.43 66620 14959 3 1192.62479 398.5493 T-complex protein 1 subunit delta OS=Homo sapiens OX=9606 GN=CCT4 PE=1 SV=4 6.46 2691.9 - 711114 - - - -1.1797 - 1.587 0.249 - 177.3 1 2 0 -0.0014 10 0 0 0 2.44E+06 5.73E+06 - - - 2.6645 1 221125_WJC_METTL3_EV_vs_WT_F05.14960.14960.2 1.09E-10 15/24 F.NDTFVHVTDLSGK.E "sp|P62263|RS14_HUMAN,tr|A0A2R8Y811|A0A2R8Y811_HUMAN,tr|E5RH77|E5RH77_HUMAN" 3 1431.6994 2.64 66621 14960 2 1431.701377 716.857 40S ribosomal protein S14 OS=Homo sapiens OX=9606 GN=RPS14 PE=1 SV=3 5.21 2692.1 - 515189 - - - 1.3753 - 3.138 0.684 - 994.8 1 1 0 0.002 13 0 0 0 1.23E+07 4.67E+06 - - - 7.0275 0.9691 221125_WJC_METTL3_EV_vs_WT_F05.14961.14961.3 0.346 13/52 R.EVLQNQLGIRPPTR.T sp|Q7Z6Z7|HUWE1_HUMAN 1 1619.9107 1.19 66622 14961 3 1619.908529 540.9775 E3 ubiquitin-protein ligase HUWE1 OS=Homo sapiens OX=9606 GN=HUWE1 PE=1 SV=3 9.7 2692.2 - 512669 - - - -1.3637 - 1.706 0.115 - 225.7 1 2 0 -0.0022 14 0 0 0 7.97E+06 6.71E+06 - - - 1.2411 1 221125_WJC_METTL3_EV_vs_WT_F05.14962.14962.2 1.46E-07 17/24 R.AHLSENELEALEK.N sp|P98175|RBM10_HUMAN 1 1481.7362 0.66 66623 14962 2 1481.739159 741.8754 RNA-binding protein 10 OS=Homo sapiens OX=9606 GN=RBM10 PE=1 SV=3 4.48 2692.3 - 499781 - - - 2.0051 - 3.358 0.651 - 767 1 2 0 0.003 13 0 0 0 4.13E+06 6.30E+06 - - - 6.9573 0.9943 221125_WJC_METTL3_EV_vs_WT_F05.14963.14963.3 3.46E-07 Dec-60 K.GDQENVHPDVMLVQPR[166.11].V "sp|Q14974|IMB1_HUMAN,tr|J3KTM9|J3KTM9_HUMAN" 2 1842.8922 1.71 66624 14963 3 1843.893428 615.3047 Importin subunit beta-1 OS=Homo sapiens OX=9606 GN=KPNB1 PE=1 SV=2 4.54 2692.4 - 356562 - - - 543.2911 - 2.225 0.387 - 197.1 1 2 0 1.0012 16 0 0 0 1.20E+07 7.01E+06 - - - 4.6294 1 221125_WJC_METTL3_EV_vs_WT_F05.14965.14965.3 3.56E-07 Nov-40 K.HGEIDYEAIVK[136.11].L "sp|P62333|PRS10_HUMAN,tr|A0A087X2I1|A0A087X2I1_HUMAN" 2 1280.6492 0.6 66626 14965 3 1280.650663 427.8903 26S proteasome regulatory subunit 10B OS=Homo sapiens OX=9606 GN=PSMC6 PE=1 SV=1 4.65 2692.7 - 318903 - - - 1.1291 - 2.301 0.561 - 156.8 1 2 0 0.0014 11 0 0 0 5.26E+06 8.70E+06 - - - 7.1616 0.9999 221125_WJC_METTL3_EV_vs_WT_F05.14967.14967.3 5.21E-05 13/52 R.NLDIER[166.11]PTYTNLNR[166.11].L "sp|Q9NY65|TBA8_HUMAN,sp|Q6PEY2|TBA3E_HUMAN,sp|P0DPH7|TBA3C_HUMAN,sp|Q71U36|TBA1A_HUMAN,sp|P0DPH8|TBA3D_HUMAN,sp|Q9H853|TBA4B_HUMAN,sp|P68366|TBA4A_HUMAN,sp|P68363|TBA1B_HUMAN,sp|Q9BQE3|TBA1C_HUMAN,tr|F8VVB9|F8VVB9_HUMAN,tr|C9JDS9|C9JDS9_HUMAN,tr|A0A7P0TA31|A0A7P0TA31_HUMAN,tr|F5H5D3|F5H5D3_HUMAN,tr|C9J2C0|C9J2C0_HUMAN,tr|F8VQQ4|F8VQQ4_HUMAN,tr|A0A7P0T945|A0A7P0T945_HUMAN" 16 1737.8913 0.6 66627 14967 3 1737.891666 580.3044 Tubulin alpha-8 chain OS=Homo sapiens OX=9606 GN=TUBA8 PE=1 SV=1 6.07 2692.9 - 3.84E+06 - - - 0.2181 - 2.325 0.413 - 226.3 1 2 0 0.0004 14 0 0 0 5.17E+08 8.59E+08 - - - 5.3867 0.9988 221125_WJC_METTL3_EV_vs_WT_F05.14969.14969.3 0.00165 Oct-36 R.IKFEMEQNLR.Q "sp|P35527|K1C9_HUMAN,tr|K7EQQ3|K7EQQ3_HUMAN" 2 1306.6704 68.24 66628 14969 3 1306.670663 436.5641 "Keratin, type I cytoskeletal 9 OS=Homo sapiens OX=9606 GN=KRT9 PE=1 SV=3" 6.14 2693.1 - 2.08E+07 - - - 0.2342 - 2.105 0.327 - 189.5 1 2 1 0.0003 10 0 0 0 2.62E+08 3.84E+06 - - - 4.3594 0.9977 221125_WJC_METTL3_EV_vs_WT_F05.14973.14973.2 3.01E-06 15/20 K.HGEIDYEAIVK[136.11].L "sp|P62333|PRS10_HUMAN,tr|A0A087X2I1|A0A087X2I1_HUMAN" 2 1280.6492 0.54 66632 14973 2 1280.642883 641.3319 26S proteasome regulatory subunit 10B OS=Homo sapiens OX=9606 GN=PSMC6 PE=1 SV=1 4.65 2693.5 - 1.22E+06 - - - -4.9459 - 2.378 0.467 - 618.9 1 2 0 -0.0063 11 0 0 0 6.45E+06 1.20E+07 - - - 4.8317 1 221125_WJC_METTL3_EV_vs_WT_F05.14974.14974.3 2.18E-08 13/40 R.DQFNSHIQLVR[166.11].N "sp|Q8ND24|RN214_HUMAN,tr|E9PN76|E9PN76_HUMAN" 2 1365.7029 2.01 66633 14974 3 1365.702135 456.2416 RING finger protein 214 OS=Homo sapiens OX=9606 GN=RNF214 PE=1 SV=2 6.74 2693.6 - 1.02E+06 - - - -0.5367 - 2.593 0.561 - 260.6 1 2 0 -0.0007 11 0 0 0 2.77E+07 1.38E+07 - - - 7.5012 1 221125_WJC_METTL3_EV_vs_WT_F05.14977.14977.3 3.97E-07 14/64 R.IQTLPNQNQSQTQPLLK.T "sp|Q8IX12|CCAR1_HUMAN,tr|F5H2E6|F5H2E6_HUMAN,tr|F5H1H2|F5H1H2_HUMAN,tr|A0A0C4DGG8|A0A0C4DGG8_HUMAN,tr|F5H3E1|F5H3E1_HUMAN" 5 1950.0534 5.16 66636 14977 3 1950.05541 651.0251 Cell division cycle and apoptosis regulator protein 1 OS=Homo sapiens OX=9606 GN=CCAR1 PE=1 SV=2 8.75 2693.9 - 709278 - - - 1.0102 - 2.675 0.595 - 209.9 1 2 0 0.002 17 0 0 0 2.66E+08 5.15E+07 - - - 7.6589 0.9999 221125_WJC_METTL3_EV_vs_WT_F05.14978.14978.2 9.26E-06 22-Dec K.SDFQVNLNNASR.S "sp|O60716|CTND1_HUMAN,tr|A0A669KB62|A0A669KB62_HUMAN,tr|A0A804HK15|A0A804HK15_HUMAN,tr|A0A669KB05|A0A669KB05_HUMAN,tr|C9JZR2|C9JZR2_HUMAN,tr|H0YC95|H0YC95_HUMAN,tr|A0A804HIL4|A0A804HIL4_HUMAN" 7 1363.648 1.06 66637 14978 2 1363.648707 682.8313 Catenin delta-1 OS=Homo sapiens OX=9606 GN=CTNND1 PE=1 SV=1 5.55 2694.1 - 566955 - - - 0.4884 - 2.22 0.531 - 446.7 1 2 0 0.0007 12 0 0 0 4.93E+06 4.66E+06 - - - 5.0611 1 221125_WJC_METTL3_EV_vs_WT_F05.14982.14982.2 6.74E-09 15/20 K.HGEIDYEAIVK.L "sp|P62333|PRS10_HUMAN,tr|A0A087X2I1|A0A087X2I1_HUMAN" 2 1272.635 0.5 66641 14982 2 1272.634582 637.3248 26S proteasome regulatory subunit 10B OS=Homo sapiens OX=9606 GN=PSMC6 PE=1 SV=1 4.65 2694.6 - 494595 - - - -0.3418 - 3.126 0.575 - 779.3 1 2 0 -0.0004 11 0 0 0 6.00E+06 1.20E+07 - - - 6.3711 1 221125_WJC_METTL3_EV_vs_WT_F05.14983.14983.2 3.36E-08 15/26 R.NQDATVYVGGLDEK[136.11].V sp|Q15427|SF3B4_HUMAN 1 1515.7297 0.82 66642 14983 2 1515.726901 758.8721 Splicing factor 3B subunit 4 OS=Homo sapiens OX=9606 GN=SF3B4 PE=1 SV=1 4.03 2694.7 - 361670 - - - -1.815 - 3.207 0.58 - 993.3 1 2 0 -0.0028 14 0 0 0 5.87E+07 7.11E+07 - - - 6.2484 1 221125_WJC_METTL3_EV_vs_WT_F05.14985.14985.3 1.96E-07 13/52 R.C[160.03]PAC[160.03]FVGTITGDR[166.11]R[166.11].L sp|O15067|PUR4_HUMAN 1 1628.7666 0.31 66644 14985 3 1628.764028 543.9295 Phosphoribosylformylglycinamidine synthase OS=Homo sapiens OX=9606 GN=PFAS PE=1 SV=4 8.07 2695 - 342355 - - - -1.592 - 2.435 0.543 - 323.5 1 2 0 -0.0026 14 0 0 0 4.60E+06 1.50E+07 - - - 6.9583 1 221125_WJC_METTL3_EV_vs_WT_F05.14988.14988.2 3.75E-15 18/38 R.FSSC[160.03]GGGGGSFGAGGGFGSR.S sp|P04264|K2C1_HUMAN 1 1764.7274 999 66646 14988 2 1764.727327 883.371 "Keratin, type II cytoskeletal 1 OS=Homo sapiens OX=9606 GN=KRT1 PE=1 SV=6" 8.25 2695.3 - 1.23E+06 - - - -0.0589 - 4.014 0.774 - 1021.8 1 2 0 -0.0001 20 0 0 0 5.47E+07 0.00E+00 - - - 8.1746 0.9999 221125_WJC_METTL3_EV_vs_WT_F05.14991.14991.3 0.000309 Nov-40 R.DQFNSHIQLVR.N "sp|Q8ND24|RN214_HUMAN,tr|E9PN76|E9PN76_HUMAN" 2 1355.6946 1.95 66648 14991 3 1355.693741 452.9055 RING finger protein 214 OS=Homo sapiens OX=9606 GN=RNF214 PE=1 SV=2 6.74 2695.6 - 2.66E+06 - - - -0.6321 - 2.421 0.417 - 257.2 1 2 0 -0.0009 11 0 0 0 2.79E+07 1.43E+07 - - - 5.7007 1 221125_WJC_METTL3_EV_vs_WT_F05.14994.14994.2 2.49E-09 15/32 R.IQTLPNQNQSQTQPLLK.T "sp|Q8IX12|CCAR1_HUMAN,tr|F5H2E6|F5H2E6_HUMAN,tr|F5H1H2|F5H1H2_HUMAN,tr|A0A0C4DGG8|A0A0C4DGG8_HUMAN,tr|F5H3E1|F5H3E1_HUMAN" 5 1950.0534 5.63 66651 14994 2 1950.052623 976.034 Cell division cycle and apoptosis regulator protein 1 OS=Homo sapiens OX=9606 GN=CCAR1 PE=1 SV=2 8.75 2695.9 - 887170 - - - -0.419 - 2.985 0.594 - 623.5 1 2 0 -0.0008 17 0 0 0 7.69E+07 1.37E+07 - - - 6.1167 1 221125_WJC_METTL3_EV_vs_WT_F05.14996.14996.3 3.89E-08 16/60 K.GDQENVHPDVMLVQPR.V "sp|Q14974|IMB1_HUMAN,tr|J3KTM9|J3KTM9_HUMAN" 2 1832.8839 1.74 66653 14996 3 1832.879273 611.9686 Importin subunit beta-1 OS=Homo sapiens OX=9606 GN=KPNB1 PE=1 SV=2 4.54 2696.2 - 605880 - - - -2.5414 - 2.987 0.667 - 339.5 1 2 0 -0.0047 16 0 0 0 1.24E+07 7.14E+06 - - - 8.7828 1 221125_WJC_METTL3_EV_vs_WT_F05.14997.14997.3 8.27E-06 22/64 K.LQALANEQAAAAHELEK.M sp|Q86UP2|KTN1_HUMAN 1 1805.9272 1.6 66654 14997 3 1805.925363 602.983 Kinectin OS=Homo sapiens OX=9606 GN=KTN1 PE=1 SV=1 4.75 2696.3 - 542120 - - - -1.0039 - 3.591 0.503 - 632.8 1 2 0 -0.0018 17 0 0 0 1.73E+07 1.08E+07 - - - 7.3772 0.9998 221125_WJC_METTL3_EV_vs_WT_F05.14999.14999.3 0.00931 21/56 K.GFSLLATEDK[136.11]EALK[136.11]K[136.11].Q "sp|P09874|PARP1_HUMAN,tr|A0A7I2V5E9|A0A7I2V5E9_HUMAN,tr|A0A7I2V625|A0A7I2V625_HUMAN,tr|A0A7I2V3E1|A0A7I2V3E1_HUMAN" 4 1672.9462 1.02 66656 14999 3 1672.944805 558.656 Poly [ADP-ribose] polymerase 1 OS=Homo sapiens OX=9606 GN=PARP1 PE=1 SV=4 6.18 2696.6 - 418680 - - - -0.8261 - 2.789 0.432 - 503.9 1 2 1 -0.0014 15 0 0 0 1.16E+08 1.13E+08 - - - 6.0324 0.9999 221125_WJC_METTL3_EV_vs_WT_F05.15005.15005.4 4.77E-06 19/84 K.GFSLLATEDKEALKK.Q "sp|P09874|PARP1_HUMAN,tr|A0A7I2V5E9|A0A7I2V5E9_HUMAN,tr|A0A7I2V625|A0A7I2V625_HUMAN,tr|A0A7I2V3E1|A0A7I2V3E1_HUMAN" 4 1648.9036 1.02 66660 15005 4 1648.901901 413.2332 Poly [ADP-ribose] polymerase 1 OS=Homo sapiens OX=9606 GN=PARP1 PE=1 SV=4 6.18 2697.2 - 1.53E+06 - - - -1.0225 - 3.175 0.546 - 219.1 1 2 1 -0.0017 15 0 0 0 1.59E+08 1.56E+08 - - - 4.3913 0.9977 221125_WJC_METTL3_EV_vs_WT_F05.15007.15007.3 0.155 Nov-64 R.IQTLPNQNQSQTQPLLK[136.11].T "sp|Q8IX12|CCAR1_HUMAN,tr|F5H2E6|F5H2E6_HUMAN,tr|F5H1H2|F5H1H2_HUMAN,tr|A0A0C4DGG8|A0A0C4DGG8_HUMAN,tr|F5H3E1|F5H3E1_HUMAN" 5 1958.0676 5.15 66662 15007 3 1958.063756 653.6965 Cell division cycle and apoptosis regulator protein 1 OS=Homo sapiens OX=9606 GN=CCAR1 PE=1 SV=2 8.75 2697.4 - 2.07E+06 - - - -1.9836 - 1.865 0.27 - 106.9 1 2 0 -0.0039 17 0 0 0 2.65E+08 5.15E+07 - - - 3.1237 0.9992 221125_WJC_METTL3_EV_vs_WT_F05.15009.15009.2 0.000169 18-Oct K.YEELQVTVGR.H sp|P35908|K22E_HUMAN 1 1192.6088 2.8 66664 15009 2 1192.604416 597.3117 "Keratin, type II cytoskeletal 2 epidermal OS=Homo sapiens OX=9606 GN=KRT2 PE=1 SV=2" 4.53 2697.6 - 822671 - - - -3.6777 - 2.222 0.502 - 408.5 1 2 0 -0.0044 10 0 0 0 3.96E+07 1.41E+07 - - - 4.976 0.9984 221125_WJC_METTL3_EV_vs_WT_F05.15014.15014.4 2.31E-05 19/84 K.GFSLLATEDK[136.11]EALK[136.11]K[136.11].Q "sp|P09874|PARP1_HUMAN,tr|A0A7I2V5E9|A0A7I2V5E9_HUMAN,tr|A0A7I2V625|A0A7I2V625_HUMAN,tr|A0A7I2V3E1|A0A7I2V3E1_HUMAN" 4 1672.9462 1.03 66668 15014 4 1672.941856 419.2438 Poly [ADP-ribose] polymerase 1 OS=Homo sapiens OX=9606 GN=PARP1 PE=1 SV=4 6.18 2698.1 - 3.09E+06 - - - -2.5888 - 3.287 0.37 - 198.7 1 2 1 -0.0043 15 0 0 0 1.59E+08 1.55E+08 - - - 2.8711 0.9998 221125_WJC_METTL3_EV_vs_WT_F05.15018.15018.3 1.19E-06 15/36 R.NNR[166.11]FPNLQLR[166.11].D "sp|Q8TB72|PUM2_HUMAN,tr|A0A0C4DG68|A0A0C4DG68_HUMAN" 2 1290.706 1.33 66670 15018 3 1290.703185 431.2426 Pumilio homolog 2 OS=Homo sapiens OX=9606 GN=PUM2 PE=1 SV=2 12 2698.6 - 1.01E+06 - - - -2.1756 - 2.913 0.495 - 426.1 1 2 1 -0.0028 10 0 0 0 1.18E+08 8.91E+07 - - - 7.1805 1 221125_WJC_METTL3_EV_vs_WT_F05.15019.15019.3 0.000161 Dec-44 R.VVDLMAHMASK[136.11]E.- "sp|P04406|G3P_HUMAN,tr|E7EUT5|E7EUT5_HUMAN" 2 1337.6563 5.3 66671 15019 3 1337.653928 446.8927 Glyceraldehyde-3-phosphate dehydrogenase OS=Homo sapiens OX=9606 GN=GAPDH PE=1 SV=3 5.51 2698.8 - 915303 - - - -1.768 - 2.168 0.547 - 141.1 1 2 0 -0.0024 12 0 0 0 1.49E+08 2.81E+07 - - - 6.7827 1 221125_WJC_METTL3_EV_vs_WT_F05.15021.15021.3 0.000197 15/64 K.VTHGLVTVEGQLTSDER.G sp|O43303|CP110_HUMAN 1 1839.9327 13.63 66673 15021 3 1839.931339 614.3182 Centriolar coiled-coil protein of 110 kDa OS=Homo sapiens OX=9606 GN=CCP110 PE=1 SV=3 4.65 2699 - 529283 - - - -0.7158 - 3.348 0.529 - 338.4 1 2 0 -0.0013 17 0 0 0 1.62E+07 1.19E+06 - - - 7.4902 0.9993 221125_WJC_METTL3_EV_vs_WT_F05.15026.15026.2 1.82E-05 13/26 K.STGGAPTFNVTVTK[136.11].T "sp|P07737|PROF1_HUMAN,tr|K7EJ44|K7EJ44_HUMAN" 2 1386.7234 1.27 66676 15026 2 1386.718978 694.369 Profilin-1 OS=Homo sapiens OX=9606 GN=PFN1 PE=1 SV=2 8.47 2699.7 - 1.45E+06 - - - -3.2213 - 2.416 0.469 - 512 1 2 0 -0.0045 14 0 0 0 8.47E+07 6.69E+07 - - - 4.7173 1 221125_WJC_METTL3_EV_vs_WT_F05.15030.15030.3 4.17E-05 25/84 K.DHTPSQELALTQSVGGDSSADR[166.11].L "sp|Q86U44|MTA70_HUMAN,tr|H0YFV6|H0YFV6_HUMAN" 2 2280.0494 0.01 66678 15030 3 2281.03666 761.0237 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 4.22 2700.2 - 2.16E+06 - - - 433.0139 - 4.726 0.638 - 672.4 1 2 0 0.9873 22 0 0 0 2.41E+05 4.31E+07 - - - 9.0617 0.9999 221125_WJC_METTL3_EV_vs_WT_F05.15033.15033.2 3.89E-10 28-Dec R.STATVQIC[160.03]SGSVNLK.G sp|Q5SWX8|ODR4_HUMAN 1 1563.7927 3.31 66681 15033 2 1563.792083 782.9036 Protein odr-4 homolog OS=Homo sapiens OX=9606 GN=ODR4 PE=1 SV=1 7.94 2700.6 - 606062 - - - -0.3671 - 2.738 0.468 - 466.3 1 2 0 -0.0006 15 0 0 0 1.05E+07 3.19E+06 - - - 4.9738 1 221125_WJC_METTL3_EV_vs_WT_F05.15038.15038.3 3.42E-05 Nov-44 R.RTTYLVLDEADR.M "sp|P17844|DDX5_HUMAN,tr|A0A7I2V5F5|A0A7I2V5F5_HUMAN,tr|J3KRZ1|J3KRZ1_HUMAN,tr|J3QSF1|J3QSF1_HUMAN,tr|A0A7I2V507|A0A7I2V507_HUMAN,tr|J3KTA4|J3KTA4_HUMAN,tr|A0A0G2JLI4|A0A0G2JLI4_HUMAN,tr|A0A7I2V2S0|A0A7I2V2S0_HUMAN" 8 1450.7416 1.6 66684 15038 3 1450.739294 484.5878 Probable ATP-dependent RNA helicase DDX5 OS=Homo sapiens OX=9606 GN=DDX5 PE=1 SV=1 4.56 2701.2 - 650689 - - - -1.5944 - 2.504 0.509 - 298.1 1 2 0 -0.0023 12 0 0 0 1.45E+07 9.03E+06 - - - 6.7585 0.9994 221125_WJC_METTL3_EV_vs_WT_F05.15042.15042.3 0.0136 Sep-40 R.NLFIGHFHTPK[136.11].N "sp|Q15643|TRIPB_HUMAN,tr|H0YJ97|H0YJ97_HUMAN" 2 1317.7073 0.91 66688 15042 3 1317.706754 440.2431 Thyroid receptor-interacting protein 11 OS=Homo sapiens OX=9606 GN=TRIP11 PE=1 SV=3 8.76 2701.6 - 506363 - - - -0.4455 - 1.793 0.317 - 90.6 1 2 0 -0.0006 11 0 0 0 4.95E+07 5.46E+07 - - - 3.7328 0.9999 221125_WJC_METTL3_EV_vs_WT_F05.15045.15045.3 8.86E-05 14/36 R.NNRFPNLQLR.D "sp|Q8TB72|PUM2_HUMAN,tr|A0A0C4DG68|A0A0C4DG68_HUMAN" 2 1270.6895 1.27 66689 15045 3 1270.688161 424.5704 Pumilio homolog 2 OS=Homo sapiens OX=9606 GN=PUM2 PE=1 SV=2 12 2702 - 2.54E+06 - - - -1.0168 - 2.967 0.484 - 486.3 1 2 1 -0.0013 10 0 0 0 1.19E+08 9.41E+07 - - - 7.1119 1 221125_WJC_METTL3_EV_vs_WT_F05.15046.15046.2 2.47E-05 17/30 Y.GSGLGIGGGFSSSSGR.A sp|P48668|K2C6C_HUMAN 1 1381.6586 999 66690 15046 2 1381.655402 691.8366 "Keratin, type II cytoskeletal 6C OS=Homo sapiens OX=9606 GN=KRT6C PE=1 SV=3" 9.75 2702.1 - 1.32E+06 - - - -2.319 - 2.906 0.565 - 633.9 1 1 0 -0.0032 16 0 0 0 2.72E+07 0.00E+00 - - - 5.8358 1 221125_WJC_METTL3_EV_vs_WT_F05.15047.15047.2 8.32E-10 16/32 R.ISIGGGSC[160.03]AISGGYGSR.A "sp|P48668|K2C6C_HUMAN,sp|P04259|K2C6B_HUMAN,sp|P02538|K2C6A_HUMAN" 3 1597.7519 999 66691 15047 2 1597.745012 799.8832 "Keratin, type II cytoskeletal 6C OS=Homo sapiens OX=9606 GN=KRT6C PE=1 SV=3" 8.22 2702.1 - 5.12E+06 - - - -4.2829 - 3.502 0.6 - 791.4 1 2 0 -0.0068 17 0 0 0 3.27E+09 0.00E+00 - - - 6.5518 0.9999 221125_WJC_METTL3_EV_vs_WT_F05.15049.15049.2 4.89E-07 14/32 R.IQTLPNQNQSQTQPLLK[136.11].T "sp|Q8IX12|CCAR1_HUMAN,tr|F5H2E6|F5H2E6_HUMAN,tr|F5H1H2|F5H1H2_HUMAN,tr|A0A0C4DGG8|A0A0C4DGG8_HUMAN,tr|F5H3E1|F5H3E1_HUMAN" 5 1958.0676 5.63 66693 15049 2 1958.067809 980.0411 Cell division cycle and apoptosis regulator protein 1 OS=Homo sapiens OX=9606 GN=CCAR1 PE=1 SV=2 8.75 2702.4 - 547233 - - - 0.0863 - 2.881 0.51 - 471.8 1 2 0 0.0002 17 0 0 0 7.69E+07 1.37E+07 - - - 5.4093 1 221125_WJC_METTL3_EV_vs_WT_F05.15050.15050.3 3.25E-06 14/40 K.YNPTWHC[160.03]IVGR[166.11].N "sp|Q96FJ2|DYL2_HUMAN,sp|P63167|DYL1_HUMAN" 2 1411.6695 1.03 66694 15050 3 1411.667465 471.5638 "Dynein light chain 2, cytoplasmic OS=Homo sapiens OX=9606 GN=DYNLL2 PE=1 SV=1" 8.23 2702.5 - 465654 - - - -1.4125 - 2.401 0.475 - 300 1 2 0 -0.002 11 0 0 0 1.22E+07 1.18E+07 - - - 6.3235 0.9999 221125_WJC_METTL3_EV_vs_WT_F05.15053.15053.3 0.000119 Dec-44 R.R[166.11]TTYLVLDEADR[166.11].M "sp|P17844|DDX5_HUMAN,tr|A0A7I2V5F5|A0A7I2V5F5_HUMAN,tr|J3KRZ1|J3KRZ1_HUMAN,tr|J3QSF1|J3QSF1_HUMAN,tr|A0A7I2V507|A0A7I2V507_HUMAN,tr|J3KTA4|J3KTA4_HUMAN,tr|A0A0G2JLI4|A0A0G2JLI4_HUMAN,tr|A0A7I2V2S0|A0A7I2V2S0_HUMAN" 8 1470.7581 1.58 66695 15053 3 1470.75374 491.26 Probable ATP-dependent RNA helicase DDX5 OS=Homo sapiens OX=9606 GN=DDX5 PE=1 SV=1 4.56 2702.9 - 539024 - - - -2.9964 - 2.366 0.477 - 177.3 1 2 0 -0.0044 12 0 0 0 1.41E+07 8.94E+06 - - - 6.244 0.9998 221125_WJC_METTL3_EV_vs_WT_F05.15054.15054.3 5.78E-05 14/40 K.TTLLHMLK[136.11]DDR[166.11].L "sp|Q9NR31|SAR1A_HUMAN,sp|Q9Y6B6|SAR1B_HUMAN,tr|D6RAA2|D6RAA2_HUMAN,tr|D6RD69|D6RD69_HUMAN,tr|X1WI22|X1WI22_HUMAN,tr|Q5SQT8|Q5SQT8_HUMAN,tr|D6RDB2|D6RDB2_HUMAN" 7 1359.7299 1.39 66696 15054 3 1359.728339 454.2506 GTP-binding protein SAR1a OS=Homo sapiens OX=9606 GN=SAR1A PE=1 SV=1 6.41 2703.1 - 797053 - - - -1.1782 - 2.822 0.409 - 384.9 1 2 1 -0.0016 11 0 0 0 2.06E+07 1.49E+07 - - - 6.0467 1 221125_WJC_METTL3_EV_vs_WT_F05.15057.15057.3 3.60E-07 20/60 R.LHNQQALSSSIEEGLR[166.11].M sp|Q06587|RING1_HUMAN 1 1790.915 1.47 66699 15057 3 1790.919059 597.979 E3 ubiquitin-protein ligase RING1 OS=Homo sapiens OX=9606 GN=RING1 PE=1 SV=2 5.4 2703.4 - 750591 - - - 2.2413 - 3.688 0.579 - 679.9 1 2 0 0.004 16 0 0 0 4.07E+07 2.78E+07 - - - 8.3428 0.9926 221125_WJC_METTL3_EV_vs_WT_F05.15060.15060.3 0.00136 Dec-48 T.FTTFDLGGHEQAR.R "sp|Q9NR31|SAR1A_HUMAN,tr|Q5SQT8|Q5SQT8_HUMAN" 2 1477.695 1.52 66702 15060 3 1477.693902 493.5723 GTP-binding protein SAR1a OS=Homo sapiens OX=9606 GN=SAR1A PE=1 SV=1 5.32 2703.8 - 379655 - - - -0.7376 - 2.376 0.417 - 114.1 1 1 0 -0.0011 13 0 0 0 3.91E+06 2.57E+06 - - - 5.5352 1 221125_WJC_METTL3_EV_vs_WT_F05.15063.15063.3 0.0895 21/60 R.LHNQQALSSSIEEGLR.M sp|Q06587|RING1_HUMAN 1 1780.9068 1.41 66704 15063 3 1780.90254 594.6429 E3 ubiquitin-protein ligase RING1 OS=Homo sapiens OX=9606 GN=RING1 PE=1 SV=2 5.4 2704.2 - 1.72E+06 - - - -2.378 - 3.872 0.575 - 935.2 1 2 0 -0.0042 16 0 0 0 3.94E+07 2.79E+07 - - - 8.4231 0.9994 221125_WJC_METTL3_EV_vs_WT_F05.15065.15065.3 7.05E-05 Nov-64 R.ISIGGGSC[160.03]AISGGYGSR.A "sp|P48668|K2C6C_HUMAN,sp|P04259|K2C6B_HUMAN,sp|P02538|K2C6A_HUMAN" 3 1597.7519 238.81 66705 15065 3 1597.756257 533.5912 "Keratin, type II cytoskeletal 6C OS=Homo sapiens OX=9606 GN=KRT6C PE=1 SV=3" 8.22 2704.4 - 3.45E+06 - - - 2.7551 - 2.246 0.365 - 108.2 1 2 0 0.0044 17 0 0 0 3.11E+08 1.30E+06 - - - 4.6523 0.9999 221125_WJC_METTL3_EV_vs_WT_F05.15068.15068.3 9.44E-07 16/60 K.VVSISSEHLEPITPTK[136.11].N sp|O00267|SPT5H_HUMAN 1 1743.9498 0.71 66708 15068 3 1743.954681 582.3239 Transcription elongation factor SPT5 OS=Homo sapiens OX=9606 GN=SUPT5H PE=1 SV=1 5.4 2704.8 - 781594 - - - 2.7896 - 2.649 0.516 - 221.1 1 2 0 0.0049 16 0 0 0 1.28E+07 1.82E+07 - - - 6.7912 0.9999 221125_WJC_METTL3_EV_vs_WT_F05.15069.15069.3 6.46E-05 Dec-40 K.YNPTWHC[160.03]IVGR.N "sp|Q96FJ2|DYL2_HUMAN,sp|P63167|DYL1_HUMAN" 2 1401.6612 1.03 66709 15069 3 1401.656397 468.2277 "Dynein light chain 2, cytoplasmic OS=Homo sapiens OX=9606 GN=DYNLL2 PE=1 SV=1" 8.23 2704.9 - 625560 - - - -3.4188 - 2.428 0.521 - 203 1 2 0 -0.0048 11 0 0 0 1.22E+07 1.18E+07 - - - 6.8673 0.9902 221125_WJC_METTL3_EV_vs_WT_F05.15071.15071.3 0.0114 Oct-48 K.DLVKNEELEIQEK.Q "sp|Q9HAW4|CLSPN_HUMAN,tr|E7ESG2|E7ESG2_HUMAN" 2 1585.8199 1.05 66711 15071 3 1585.814601 529.6139 Claspin OS=Homo sapiens OX=9606 GN=CLSPN PE=1 SV=3 4.25 2705.2 - 346146 - - - -3.3522 - 1.703 0.353 - 82.2 1 2 1 -0.0053 13 0 0 0 5.49E+06 5.21E+06 - - - 3.9176 0.9999 221125_WJC_METTL3_EV_vs_WT_F05.15076.15076.3 2.36E-05 13/56 R.ADMEDLMSSK[136.11]DDVGK[136.11].N sp|P35580|MYH10_HUMAN 1 1655.7353 1.41 66714 15076 3 1655.73418 552.9191 Myosin-10 OS=Homo sapiens OX=9606 GN=MYH10 PE=1 SV=3 4.04 2705.8 - 941226 - - - -0.6994 - 2.292 0.52 - 130.3 1 2 1 -0.0012 15 0 0 0 1.40E+07 9.96E+06 - - - 6.5014 1 221125_WJC_METTL3_EV_vs_WT_F05.15077.15077.3 0.00011 17/64 R.AHTLLSPPSANNATFAR.V "sp|P49005|DPOD2_HUMAN,tr|A0A087WWF6|A0A087WWF6_HUMAN,tr|C9J8Z7|C9J8Z7_HUMAN,tr|F8W8R3|F8W8R3_HUMAN,tr|C9JHC7|C9JHC7_HUMAN,tr|C9IZD2|C9IZD2_HUMAN,tr|C9JLE1|C9JLE1_HUMAN" 7 1766.9064 1.24 66715 15077 3 1766.904535 589.9761 DNA polymerase delta subunit 2 OS=Homo sapiens OX=9606 GN=POLD2 PE=1 SV=1 9.8 2706 - 914996 - - - -1.0448 - 2.773 0.477 - 360.6 1 2 0 -0.0018 17 0 0 0 1.01E+07 8.10E+06 - - - 6.4342 0.9999 221125_WJC_METTL3_EV_vs_WT_F05.15081.15081.3 0.000781 15/44 R.QLQQELADTLKK.Q "sp|Q9UPS8|ANR26_HUMAN,tr|A0A6Q8PG48|A0A6Q8PG48_HUMAN,tr|A0A6Q8PFU2|A0A6Q8PFU2_HUMAN,tr|E7ESJ3|E7ESJ3_HUMAN" 4 1413.7827 3.81 66717 15081 3 1413.782192 472.2682 Ankyrin repeat domain-containing protein 26 OS=Homo sapiens OX=9606 GN=ANKRD26 PE=1 SV=4 6.07 2706.5 - 951149 - - - -0.3904 - 2.365 0.366 - 311.3 1 2 0 -0.0006 12 0 0 0 1.61E+07 4.22E+06 - - - 5.0063 0.999 221125_WJC_METTL3_EV_vs_WT_F05.15083.15083.3 0.0271 Oct-40 R.NLFIGHFHTPK.N "sp|Q15643|TRIPB_HUMAN,tr|H0YJ97|H0YJ97_HUMAN" 2 1309.6931 0.91 66719 15083 3 1309.692341 437.5717 Thyroid receptor-interacting protein 11 OS=Homo sapiens OX=9606 GN=TRIP11 PE=1 SV=3 8.76 2706.7 - 1.16E+06 - - - -0.6108 - 1.879 0.264 - 124.9 1 2 0 -0.0008 11 0 0 0 4.95E+07 5.41E+07 - - - 3.2749 0.9998 221125_WJC_METTL3_EV_vs_WT_F05.15094.15094.2 1.25E-06 24-Dec R.GDVGSADIQDLEK.W "sp|Q9Y5M8|SRPRB_HUMAN,tr|H7C4H2|H7C4H2_HUMAN" 2 1345.6361 1.22 66728 15094 2 1345.634049 673.8253 Signal recognition particle receptor subunit beta OS=Homo sapiens OX=9606 GN=SRPRB PE=1 SV=3 3.84 2708.1 - 286447 - - - -1.5532 - 2.326 0.514 - 469.1 1 2 0 -0.0021 13 0 0 0 4.95E+06 4.04E+06 - - - 5.0033 0.9999 221125_WJC_METTL3_EV_vs_WT_F05.15102.15102.3 2.72E-05 13/44 K.DIISDTSGDFRK.L "sp|P07355|ANXA2_HUMAN,sp|A6NMY6|AXA2L_HUMAN,tr|H0YL33|H0YL33_HUMAN,tr|H0YMU9|H0YMU9_HUMAN,tr|H0YNA0|H0YNA0_HUMAN,tr|H0YM50|H0YM50_HUMAN,tr|H0YMD0|H0YMD0_HUMAN,tr|H0YMW4|H0YMW4_HUMAN,tr|H0YN42|H0YN42_HUMAN,tr|H0YN28|H0YN28_HUMAN,tr|H0YNP5|H0YNP5_HUMAN,tr|H0YNB8|H0YNB8_HUMAN,tr|H0YKS4|H0YKS4_HUMAN" 13 1352.6572 5.25 66734 15102 3 1352.653498 451.893 Annexin A2 OS=Homo sapiens OX=9606 GN=ANXA2 PE=1 SV=2 4.43 2708.9 - 482406 - - - -2.7435 - 2.648 0.528 - 169.5 1 2 0 -0.0037 12 0 0 0 2.37E+07 4.52E+06 - - - 7.1249 0.9999 221125_WJC_METTL3_EV_vs_WT_F05.15103.15103.2 0.000277 28-Oct K.VAAETQSPSLFGSTK.L sp|Q9UKX7|NUP50_HUMAN 1 1521.7675 2.77 66735 15103 2 1521.766757 761.891 Nuclear pore complex protein Nup50 OS=Homo sapiens OX=9606 GN=NUP50 PE=1 SV=2 5.97 2709 - 316470 - - - -0.4804 - 2.107 0.513 - 301.8 1 2 0 -0.0007 15 0 0 0 7.65E+06 2.76E+06 - - - 4.6621 1 221125_WJC_METTL3_EV_vs_WT_F05.15108.15108.3 6.44E-08 18/52 R.K[136.11]LEVEANNAFDQYR[166.11].D "sp|P47756|CAPZB_HUMAN,tr|B1AK87|B1AK87_HUMAN,tr|B1AK88|B1AK88_HUMAN,tr|A0A6I8PRV6|A0A6I8PRV6_HUMAN,tr|B1AK85|B1AK85_HUMAN" 5 1713.8441 0.44 66738 15108 3 1713.841411 572.2886 F-actin-capping protein subunit beta OS=Homo sapiens OX=9606 GN=CAPZB PE=1 SV=4 4.68 2709.6 - 883699 - - - -1.5801 - 3.195 0.538 - 530.9 1 2 0 -0.0027 14 0 0 0 4.38E+07 1.00E+08 - - - 7.6244 1 221125_WJC_METTL3_EV_vs_WT_F05.15109.15109.2 3.91E-09 13/30 R.LSSLNQDNSLAEDNLK.L sp|Q15643|TRIPB_HUMAN 1 1759.8588 1.6 66739 15109 2 1759.855226 880.9367 Thyroid receptor-interacting protein 11 OS=Homo sapiens OX=9606 GN=TRIP11 PE=1 SV=3 4.03 2709.7 - 740278 - - - -2.0433 - 2.926 0.623 - 563.6 1 2 0 -0.0036 16 0 0 0 1.14E+07 7.14E+06 - - - 6.2809 1 221125_WJC_METTL3_EV_vs_WT_F05.15110.15110.3 5.15E-08 16/52 R.KLEVEANNAFDQYR.D "sp|P47756|CAPZB_HUMAN,tr|B1AK87|B1AK87_HUMAN,tr|B1AK88|B1AK88_HUMAN,tr|A0A6I8PRV6|A0A6I8PRV6_HUMAN,tr|B1AK85|B1AK85_HUMAN" 5 1695.8216 0.39 66740 15110 3 1695.820024 566.2812 F-actin-capping protein subunit beta OS=Homo sapiens OX=9606 GN=CAPZB PE=1 SV=4 4.68 2709.9 - 732196 - - - -0.9582 - 2.535 0.51 - 403.4 1 2 0 -0.0016 14 0 0 0 3.54E+07 9.16E+07 - - - 6.6976 0.9995 221125_WJC_METTL3_EV_vs_WT_F05.15112.15112.3 0.00471 Oct-36 K.HLTYNDFINK.E "sp|Q02880|TOP2B_HUMAN,tr|E9PCY5|E9PCY5_HUMAN" 2 1263.6248 0.92 66742 15112 3 1263.621468 422.2155 DNA topoisomerase 2-beta OS=Homo sapiens OX=9606 GN=TOP2B PE=1 SV=3 6.74 2710.1 - 404806 - - - -2.6266 - 2.245 0.342 - 153.3 1 2 0 -0.0033 10 0 0 0 6.86E+06 7.49E+06 - - - 4.7138 1 221125_WJC_METTL3_EV_vs_WT_F05.15118.15118.3 2.76E-10 16/56 K.C[160.03]IDLEPDNATTYVHK.G sp|O94826|TOM70_HUMAN 1 1774.8196 2.03 66746 15118 3 1774.820203 592.6138 Mitochondrial import receptor subunit TOM70 OS=Homo sapiens OX=9606 GN=TOMM70 PE=1 SV=1 4.54 2710.8 - 1.34E+06 - - - 0.3398 - 3.095 0.616 - 296.4 1 2 0 0.0006 15 0 0 0 3.39E+07 1.67E+07 - - - 8.3557 0.9809 221125_WJC_METTL3_EV_vs_WT_F05.15119.15119.2 3.51E-05 22-Dec R.SIFQHIQSAQSQ.R "sp|Q9Y2W1|TR150_HUMAN,tr|A0A3B3ITZ9|A0A3B3ITZ9_HUMAN" 2 1372.6735 - 66747 15119 2 1372.670391 687.344 Thyroid hormone receptor-associated protein 3 OS=Homo sapiens OX=9606 GN=THRAP3 PE=1 SV=2 6.46 2710.9 - 879189 - - - -2.2853 - 2.534 0.453 - 494.7 1 1 0 -0.0031 12 0 0 0 - - - - - 4.8323 1 221125_WJC_METTL3_EV_vs_WT_F05.15121.15121.3 2.46E-06 23/76 K.DILLQQQQQLGHGGPEAAPR[166.11].A sp|Q7Z5L9|I2BP2_HUMAN 1 2165.1217 3.31 66749 15121 3 2165.118485 722.7145 Interferon regulatory factor 2-binding protein 2 OS=Homo sapiens OX=9606 GN=IRF2BP2 PE=1 SV=2 5.32 2711.2 - 835904 - - - -1.4775 - 3.404 0.536 - 222.6 1 2 0 -0.0032 20 0 0 0 6.63E+07 2.00E+07 - - - 7.4867 0.9999 221125_WJC_METTL3_EV_vs_WT_F05.15122.15122.3 1.95E-06 16/48 K.QADLYISEGLHPR[166.11].L "sp|Q92526|TCPW_HUMAN,sp|P40227|TCPZ_HUMAN" 2 1507.7659 0.47 66750 15122 3 1507.762265 503.5959 T-complex protein 1 subunit zeta-2 OS=Homo sapiens OX=9606 GN=CCT6B PE=1 SV=5 5.32 2711.3 - 735116 - - - -2.3856 - 2.585 0.483 - 348 1 2 0 -0.0036 13 0 0 0 1.25E+07 2.66E+07 - - - 6.499 1 221125_WJC_METTL3_EV_vs_WT_F05.15124.15124.2 1.70E-06 22-Dec K.DSVFLSC[160.03]SEDNR.L "sp|Q9BQA1|MEP50_HUMAN,tr|H0Y711|H0Y711_HUMAN" 2 1427.5987 2.89 66752 15124 2 1427.599956 714.8066 Methylosome protein 50 OS=Homo sapiens OX=9606 GN=WDR77 PE=1 SV=1 4.03 2711.6 - 550289 - - - 0.8742 - 2.424 0.616 - 585.8 1 2 0 0.0012 12 0 0 0 5.67E+07 1.96E+07 - - - 5.9201 1 221125_WJC_METTL3_EV_vs_WT_F05.15129.15129.3 0.000138 15/52 K.TVPEELVK[136.11]PEELSK[136.11].Y "sp|Q9UMS4|PRP19_HUMAN,tr|H0YGF3|H0YGF3_HUMAN,tr|F5GY56|F5GY56_HUMAN" 3 1612.8895 1.38 66755 15129 3 1612.888594 538.6371 Pre-mRNA-processing factor 19 OS=Homo sapiens OX=9606 GN=PRPF19 PE=1 SV=1 4.49 2712.2 - 1.19E+06 - - - -0.5332 - 2.289 0.51 - 190.2 1 2 0 -0.0009 14 0 0 0 1.18E+08 8.58E+07 - - - 6.4265 1 221125_WJC_METTL3_EV_vs_WT_F05.15131.15131.3 1.56E-08 26/76 K.DILLQQQQQLGHGGPEAAPR.A sp|Q7Z5L9|I2BP2_HUMAN 1 2155.1134 1.92 66757 15131 3 2155.112859 719.3784 Interferon regulatory factor 2-binding protein 2 OS=Homo sapiens OX=9606 GN=IRF2BP2 PE=1 SV=2 5.32 2712.5 - 2.23E+06 - - - -0.2575 - 4.5 0.622 - 832.3 1 2 0 -0.0006 20 0 0 0 3.68E+07 1.92E+07 - - - 9.1235 1 221125_WJC_METTL3_EV_vs_WT_F05.15132.15132.3 1.43E-05 19/64 K.LSHEGPGSELPAGALYR[166.11].K "sp|Q14203|DCTN1_HUMAN,tr|A0A804CDA6|A0A804CDA6_HUMAN,tr|E7EX90|E7EX90_HUMAN,tr|A0A7P0Z4C3|A0A7P0Z4C3_HUMAN,tr|E7EWF7|E7EWF7_HUMAN" 5 1762.8878 2.07 66758 15132 3 1762.885152 588.6365 Dynactin subunit 1 OS=Homo sapiens OX=9606 GN=DCTN1 PE=1 SV=3 5.4 2712.6 - 753236 - - - -1.4839 - 2.715 0.495 - 422.8 1 2 0 -0.0026 17 0 0 0 4.51E+07 2.18E+07 - - - 6.5813 0.9997 221125_WJC_METTL3_EV_vs_WT_F05.15133.15133.3 0.00235 14/56 K.C[160.03]IDLEPDNATTYVHK[136.11].G sp|O94826|TOM70_HUMAN 1 1782.8338 2.01 66759 15133 3 1782.831871 595.2852 Mitochondrial import receptor subunit TOM70 OS=Homo sapiens OX=9606 GN=TOMM70 PE=1 SV=1 4.54 2712.7 - 653936 - - - -1.082 - 2.053 0.342 - 94 1 2 0 -0.0019 15 0 0 0 3.38E+07 1.68E+07 - - - 4.2294 0.9999 221125_WJC_METTL3_EV_vs_WT_F05.15134.15134.3 0.000254 Dec-32 K.DYAFVHMEK.E sp|Q96PK6|RBM14_HUMAN 1 1138.5117 1.79 66760 15134 3 1138.510357 380.5112 RNA-binding protein 14 OS=Homo sapiens OX=9606 GN=RBM14 PE=1 SV=2 5.32 2712.8 - 511549 - - - -1.2068 - 1.82 0.466 - 190.3 1 2 0 -0.0014 9 0 0 0 5.86E+06 3.27E+06 - - - 5.5398 1 221125_WJC_METTL3_EV_vs_WT_F05.15139.15139.3 3.55E-07 17/60 K.VSQPIEGHAASFAQFK[136.11].M "sp|Q00610|CLH1_HUMAN,tr|A0A087WVQ6|A0A087WVQ6_HUMAN" 2 1723.8773 1.16 66763 15139 3 1723.874288 575.633 Clathrin heavy chain 1 OS=Homo sapiens OX=9606 GN=CLTC PE=1 SV=5 6.72 2713.4 - 1.71E+06 - - - -1.7588 - 3.46 0.445 - 424.6 1 2 0 -0.003 16 0 0 0 9.14E+07 7.88E+07 - - - 6.6854 1 221125_WJC_METTL3_EV_vs_WT_F05.15140.15140.3 0.000454 13/44 R.GNEEAQIFRPLK.F sp|Q15029|U5S1_HUMAN 1 1400.7412 2.15 66764 15140 3 1400.739947 467.921 116 kDa U5 small nuclear ribonucleoprotein component OS=Homo sapiens OX=9606 GN=EFTUD2 PE=1 SV=1 6.14 2713.5 - 863559 - - - -0.9038 - 2.478 0.443 - 343.4 1 2 0 -0.0013 12 0 0 0 1.35E+08 6.28E+07 - - - 5.994 1 221125_WJC_METTL3_EV_vs_WT_F05.15141.15141.3 1.48E-09 18/68 K.SLIGVEYKPVSATGAEDK.D "sp|P07814|SYEP_HUMAN,tr|V9GYZ6|V9GYZ6_HUMAN" 2 1862.9626 0.89 66765 15141 3 1862.964177 621.9948 Bifunctional glutamate\proline--tRNA ligase OS=Homo sapiens OX=9606 GN=EPRS1 PE=1 SV=5 4.68 2713.7 - 686497 - - - 0.8685 - 3.117 0.638 - 276.5 1 2 0 0.0016 18 0 0 0 1.04E+07 1.16E+07 - - - 8.4835 0.9974 221125_WJC_METTL3_EV_vs_WT_F05.15143.15143.3 0.298 Oct-44 R.MSVEADINGLRR.V "sp|P02533|K1C14_HUMAN,sp|P08727|K1C19_HUMAN,tr|C9JM50|C9JM50_HUMAN,tr|K7EMS3|K7EMS3_HUMAN" 4 1359.6929 32.1 66767 15143 3 1359.692474 454.2382 "Keratin, type I cytoskeletal 14 OS=Homo sapiens OX=9606 GN=KRT14 PE=1 SV=4" 5.82 2713.9 - 609880 - - - -0.3008 - 1.954 0.202 - 204.1 1 2 0 -0.0004 12 0 0 0 8.62E+07 2.69E+06 - - - 2.6488 0.9845 221125_WJC_METTL3_EV_vs_WT_F05.15144.15144.3 0.0196 Sep-56 R.ADTQTYQPYNKDWIK.E sp|P84090|ERH_HUMAN 1 1869.8897 999 66768 15144 3 1869.89198 624.3039 Enhancer of rudimentary homolog OS=Homo sapiens OX=9606 GN=ERH PE=1 SV=1 6 2714.1 - 587100 - - - 1.2043 - 1.706 0.24 - 91.8 1 2 1 0.0023 15 0 0 0 5.54E+06 0.00E+00 - - - 2.6089 0.915 221125_WJC_METTL3_EV_vs_WT_F05.15145.15145.2 6.66 12-May K.NIFLGEK.A "sp|Q96FA3|PELI1_HUMAN,sp|Q9HAT8|PELI2_HUMAN,tr|H0YNF4|H0YNF4_HUMAN,tr|H0YK56|H0YK56_HUMAN" 4 819.4491 2.63 66769 15145 2 819.447925 410.7318 E3 ubiquitin-protein ligase pellino homolog 1 OS=Homo sapiens OX=9606 GN=PELI1 PE=1 SV=2 6 2714.2 - 480898 - - - -1.3778 - 1.158 0.02 - 51.9 3 2 0 -0.0011 7 0 0 0 8.08E+06 3.08E+06 - - - -0.56 0.9995 221125_WJC_METTL3_EV_vs_WT_F05.15148.15148.3 0.000528 Sep-40 K.QQHVIETLIGK[136.11].K "sp|P48643|TCPE_HUMAN,tr|E9PCA1|E9PCA1_HUMAN,tr|B7ZAR1|B7ZAR1_HUMAN,tr|E7ENZ3|E7ENZ3_HUMAN" 4 1272.7281 0.67 66770 15148 3 1272.726295 425.25 T-complex protein 1 subunit epsilon OS=Homo sapiens OX=9606 GN=CCT5 PE=1 SV=1 6.75 2714.6 - 6.30E+06 - - - -1.4465 - 1.895 0.324 - 148.5 1 2 0 -0.0018 11 0 0 0 4.96E+08 7.43E+08 - - - 3.9677 0.9999 221125_WJC_METTL3_EV_vs_WT_F05.15150.15150.3 0.000627 15/40 K.QQHVIETLIGK.K "sp|P48643|TCPE_HUMAN,tr|E9PCA1|E9PCA1_HUMAN,tr|B7ZAR1|B7ZAR1_HUMAN,tr|E7ENZ3|E7ENZ3_HUMAN" 4 1264.7139 0.67 66772 15150 3 1264.7127 422.5786 T-complex protein 1 subunit epsilon OS=Homo sapiens OX=9606 GN=CCT5 PE=1 SV=1 6.75 2714.7 - 4.33E+06 - - - -0.9773 - 2.156 0.423 - 342.5 1 2 0 -0.0012 11 0 0 0 4.96E+08 7.43E+08 - - - 5.4382 1 221125_WJC_METTL3_EV_vs_WT_F05.15151.15151.3 1.28E-09 16/44 R.GNEEAQIFR[166.11]PLK[136.11].F sp|Q15029|U5S1_HUMAN 1 1418.7637 2.15 66773 15151 3 1418.763512 473.9285 116 kDa U5 small nuclear ribonucleoprotein component OS=Homo sapiens OX=9606 GN=EFTUD2 PE=1 SV=1 6.14 2714.8 - 1.22E+06 - - - -0.1205 - 2.872 0.583 - 534.8 1 2 0 -0.0002 12 0 0 0 1.35E+08 6.28E+07 - - - 7.9642 0.9999 221125_WJC_METTL3_EV_vs_WT_F05.15154.15154.3 1.80E-06 17/48 K.QADLYISEGLHPR.L "sp|Q92526|TCPW_HUMAN,sp|P40227|TCPZ_HUMAN" 2 1497.7576 0.26 66776 15154 3 1497.756408 500.2598 T-complex protein 1 subunit zeta-2 OS=Homo sapiens OX=9606 GN=CCT6B PE=1 SV=5 5.32 2715.2 - 903297 - - - -0.7905 - 2.752 0.385 - 346.9 1 2 0 -0.0012 13 0 0 0 1.40E+07 5.35E+07 - - - 5.5768 1 221125_WJC_METTL3_EV_vs_WT_F05.15158.15158.4 2.37E-08 16/90 K.ALLSHDSGSDHLAFVR[166.11].A "sp|Q7L2E3|DHX30_HUMAN,tr|H7BXY3|H7BXY3_HUMAN" 2 1733.8725 1.12 66780 15158 4 1733.873049 434.4754 ATP-dependent RNA helicase DHX30 OS=Homo sapiens OX=9606 GN=DHX30 PE=1 SV=1 5.98 2715.6 - 347279 - - - 0.3443 - 2.696 0.585 - 210.2 1 2 0 0.0006 16 0 0 0 1.54E+07 1.38E+07 - - - 4.667 0.9999 221125_WJC_METTL3_EV_vs_WT_F05.15159.15159.3 0.0051 Nov-32 K.DYAFVHMEK[136.11].E sp|Q96PK6|RBM14_HUMAN 1 1146.5259 1.79 66781 15159 3 1146.524825 383.1826 RNA-binding protein 14 OS=Homo sapiens OX=9606 GN=RBM14 PE=1 SV=2 5.32 2715.8 - 324965 - - - -0.9647 - 1.917 0.437 - 200 1 2 0 -0.0011 9 0 0 0 5.86E+06 3.27E+06 - - - 5.3731 1 221125_WJC_METTL3_EV_vs_WT_F05.15163.15163.2 1.86E-05 13/22 R.GATQQILDEAER.S "sp|P78371|TCPB_HUMAN,tr|F8VQ14|F8VQ14_HUMAN,tr|F5GWF6|F5GWF6_HUMAN" 3 1329.6525 0.52 66784 15163 2 1329.649941 665.8335 T-complex protein 1 subunit beta OS=Homo sapiens OX=9606 GN=CCT2 PE=1 SV=4 4.14 2716.4 - 669278 - - - -1.893 - 2.926 0.53 - 859.2 1 2 0 -0.0025 12 0 0 0 1.38E+07 2.67E+07 - - - 5.7797 0.9999 221125_WJC_METTL3_EV_vs_WT_F05.15165.15165.3 0.000939 15/52 K.TVPEELVKPEELSK.Y "sp|Q9UMS4|PRP19_HUMAN,tr|H0YGF3|H0YGF3_HUMAN,tr|F5GY56|F5GY56_HUMAN" 3 1596.8611 1.36 66785 15165 3 1596.861604 533.2943 Pre-mRNA-processing factor 19 OS=Homo sapiens OX=9606 GN=PRPF19 PE=1 SV=1 4.49 2716.6 - 3.10E+06 - - - 0.3444 - 2.275 0.44 - 196.3 1 2 0 0.0006 14 0 0 0 1.16E+08 8.55E+07 - - - 5.6299 0.9961 221125_WJC_METTL3_EV_vs_WT_F05.15168.15168.3 0.00719 15/44 R.EDLRLPEGDLGK.E "sp|P63241|IF5A1_HUMAN,sp|Q6IS14|IF5AL_HUMAN,tr|I3L397|I3L397_HUMAN,tr|I3L504|I3L504_HUMAN" 4 1340.6936 1.17 66788 15168 3 1340.69247 447.9051 Eukaryotic translation initiation factor 5A-1 OS=Homo sapiens OX=9606 GN=EIF5A PE=1 SV=2 4.32 2716.9 - 575445 - - - -0.8391 - 2.032 0.262 - 300.2 1 2 1 -0.0011 12 0 0 0 7.26E+07 6.23E+07 - - - 3.426 0.9999 221125_WJC_METTL3_EV_vs_WT_F05.15172.15172.2 1.01E-05 14/22 R.GNEEAQIFR[166.11]PLK[136.11].F sp|Q15029|U5S1_HUMAN 1 1418.7637 2.58 66792 15172 2 1418.76566 710.3891 116 kDa U5 small nuclear ribonucleoprotein component OS=Homo sapiens OX=9606 GN=EFTUD2 PE=1 SV=1 6.14 2717.4 - 398093 - - - 1.3935 - 2.917 0.522 - 433.6 1 2 0 0.002 12 0 0 0 1.67E+07 6.45E+06 - - - 5.7127 1 221125_WJC_METTL3_EV_vs_WT_F05.15174.15174.2 1.24E-11 16/32 R.SVGGSGGGSFGDNLVTR.S "sp|P02545|LMNA_HUMAN,tr|A0A6Q8PFJ0|A0A6Q8PFJ0_HUMAN" 2 1565.7434 1.3 66794 15174 2 1565.73864 783.879 Prelamin-A\C OS=Homo sapiens OX=9606 GN=LMNA PE=1 SV=1 5.55 2717.7 - 240656 - - - -3.0388 - 3.24 0.685 - 789.1 1 2 0 -0.0048 17 0 0 0 4.12E+06 3.17E+06 - - - 6.9891 1 221125_WJC_METTL3_EV_vs_WT_F05.15176.15176.3 1.10E-07 17/64 K.LSHEGPGSELPAGALYR.K "sp|Q14203|DCTN1_HUMAN,tr|A0A804CDA6|A0A804CDA6_HUMAN,tr|E7EX90|E7EX90_HUMAN,tr|A0A7P0Z4C3|A0A7P0Z4C3_HUMAN,tr|E7EWF7|E7EWF7_HUMAN" 5 1752.8795 1.93 66795 15176 3 1752.880589 585.3004 Dynactin subunit 1 OS=Homo sapiens OX=9606 GN=DCTN1 PE=1 SV=3 5.4 2717.9 - 1.01E+06 - - - 0.6224 - 3.169 0.527 - 350.5 1 2 0 0.0011 17 0 0 0 4.63E+07 2.41E+07 - - - 7.3291 1 221125_WJC_METTL3_EV_vs_WT_F05.15178.15178.2 1.23E-07 16/20 K.QQHVIETLIGK[136.11].K "sp|P48643|TCPE_HUMAN,tr|E9PCA1|E9PCA1_HUMAN,tr|B7ZAR1|B7ZAR1_HUMAN,tr|E7ENZ3|E7ENZ3_HUMAN" 4 1272.7281 0.65 66796 15178 2 1272.727082 637.3713 T-complex protein 1 subunit epsilon OS=Homo sapiens OX=9606 GN=CCT5 PE=1 SV=1 6.75 2718.1 - 1.00E+07 - - - -0.8281 - 2.493 0.603 - 933.2 1 2 0 -0.0011 11 0 0 0 1.87E+08 2.87E+08 - - - 5.9656 1 221125_WJC_METTL3_EV_vs_WT_F05.15179.15179.3 2.95E-05 17/48 R.EQDLPLAEAVRPK.T sp|Q96A49|SYAP1_HUMAN 1 1464.7936 1.32 66797 15179 3 1464.792654 489.2718 Synapse-associated protein 1 OS=Homo sapiens OX=9606 GN=SYAP1 PE=1 SV=1 4.68 2718.2 - 999918 - - - -0.6752 - 2.5 0.461 - 526.4 1 2 0 -0.001 13 0 0 0 7.75E+07 5.89E+07 - - - 6.1638 1 221125_WJC_METTL3_EV_vs_WT_F05.15180.15180.3 9.64E-07 14/44 K.KAELDIDALNGR.N sp|Q9P2D1|CHD7_HUMAN 1 1313.6939 1.94 66798 15180 3 1313.693089 438.9053 Chromodomain-helicase-DNA-binding protein 7 OS=Homo sapiens OX=9606 GN=CHD7 PE=1 SV=3 4.56 2718.3 - 1.12E+06 - - - -0.6394 - 2.666 0.515 - 405.5 1 2 0 -0.0008 12 0 0 0 1.13E+07 5.84E+06 - - - 6.9995 1 221125_WJC_METTL3_EV_vs_WT_F05.15181.15181.3 0.00132 20/68 R.HIISATSLSTSPTELGSR[166.11].N sp|Q5JSZ5|PRC2B_HUMAN 1 1865.9722 1.78 66799 15181 3 1865.97481 622.998 Protein PRRC2B OS=Homo sapiens OX=9606 GN=PRRC2B PE=1 SV=2 6.75 2718.4 - 851949 - - - 1.3848 - 3.054 0.482 - 340.6 1 2 0 0.0026 18 0 0 0 3.94E+07 2.22E+07 - - - 6.6932 0.9999 221125_WJC_METTL3_EV_vs_WT_F05.15182.15182.2 8.36E-05 13/22 R.GNEEAQIFRPLK.F sp|Q15029|U5S1_HUMAN 1 1400.7412 2.58 66800 15182 2 1400.742773 701.3779 116 kDa U5 small nuclear ribonucleoprotein component OS=Homo sapiens OX=9606 GN=EFTUD2 PE=1 SV=1 6.14 2718.6 - 771786 - - - 1.1137 - 2.652 0.54 - 604 1 2 0 0.0016 12 0 0 0 1.67E+07 6.45E+06 - - - 5.5952 1 221125_WJC_METTL3_EV_vs_WT_F05.15184.15184.2 3.31E-07 24-Nov R.C[160.03]WEVQDSGQTIPK[136.11].A "sp|P78406|RAE1L_HUMAN,tr|B0QZ36|B0QZ36_HUMAN,tr|E9PQ57|E9PQ57_HUMAN,tr|B0QZ37|B0QZ37_HUMAN,tr|E9PPG9|E9PPG9_HUMAN" 5 1554.7228 2.46 66802 15184 2 1554.723663 778.3687 mRNA export factor OS=Homo sapiens OX=9606 GN=RAE1 PE=1 SV=1 4.37 2718.8 - 735716 - - - 0.5596 - 2.256 0.635 - 327.3 1 2 0 0.0009 13 0 0 0 3.51E+07 1.43E+07 - - - 5.8189 0.9996 221125_WJC_METTL3_EV_vs_WT_F05.15186.15186.3 0.000111 14/52 K.EPSSQLFSK[136.11]PEVIK[136.11].Q sp|Q9H6T0|ESRP2_HUMAN 1 1603.8792 2.42 66804 15186 3 1603.885538 535.6337 Epithelial splicing regulatory protein 2 OS=Homo sapiens OX=9606 GN=ESRP2 PE=1 SV=1 6.24 2719.1 - 581680 - - - 3.9367 - 2.443 0.438 - 291.5 1 2 0 0.0063 14 0 0 0 1.68E+07 6.94E+06 - - - 5.7953 1 221125_WJC_METTL3_EV_vs_WT_F05.15191.15191.3 3.77E-11 17/64 K.FYDANYDGK[136.11]EYDPVEAR[166.11].Q "sp|Q15555|MARE2_HUMAN,tr|K7ERD8|K7ERD8_HUMAN,tr|K7EL66|K7EL66_HUMAN" 3 2068.9133 0.96 66809 15191 3 2068.915035 690.6451 Microtubule-associated protein RP\EB family member 2 OS=Homo sapiens OX=9606 GN=MAPRE2 PE=1 SV=1 4.11 2719.7 - 385948 - - - 0.8285 - 2.898 0.743 - 283.3 1 2 1 0.0017 17 0 0 0 3.33E+06 3.46E+06 - - - 9.5113 0.9997 221125_WJC_METTL3_EV_vs_WT_F05.15192.15192.3 0.00208 Dec-52 R.TPENHENLFLQPPK.L sp|Q7LBC6|KDM3B_HUMAN 1 1662.8366 2.05 66810 15192 3 1662.838827 555.2861 Lysine-specific demethylase 3B OS=Homo sapiens OX=9606 GN=KDM3B PE=1 SV=2 5.37 2719.9 - 322632 - - - 1.3573 - 2.029 0.354 - 147 1 2 0 0.0023 14 0 0 0 1.61E+07 7.88E+06 - - - 4.3664 0.9999 221125_WJC_METTL3_EV_vs_WT_F05.15193.15193.3 2.51E-06 Oct-32 R.VVHIMDFQR.G "sp|P43243|MATR3_HUMAN,tr|D6RE02|D6RE02_HUMAN,tr|B3KM87|B3KM87_HUMAN,tr|A8MXP9|A8MXP9_HUMAN,tr|D6RAY2|D6RAY2_HUMAN,tr|D6R991|D6R991_HUMAN,tr|A0A0R4J2E8|A0A0R4J2E8_HUMAN,tr|D6RAM9|D6RAM9_HUMAN,tr|D6RIA2|D6RIA2_HUMAN,tr|H0Y8T4|H0Y8T4_HUMAN,tr|D6REM6|D6REM6_HUMAN,tr|D6RBI2|D6RBI2_HUMAN" 12 1143.5859 1.17 66811 15193 3 1143.583793 382.2026 Matrin-3 OS=Homo sapiens OX=9606 GN=MATR3 PE=1 SV=2 6.71 2720 - 299623 - - - -1.8416 - 2.01 0.43 - 242.9 1 2 0 -0.0021 9 0 0 0 4.93E+07 4.20E+07 - - - 5.4375 1 221125_WJC_METTL3_EV_vs_WT_F05.15197.15197.2 0.000138 14/24 R.FSGSGSGTDFTLK.L "sp|A2NJV5|KV229_HUMAN,sp|A0A087WW87|KV240_HUMAN,sp|P06310|KV230_HUMAN,sp|A0A075B6S2|KVD29_HUMAN,sp|P01614|KVD40_HUMAN,sp|P01615|KVD28_HUMAN,sp|A0A075B6S6|KVD30_HUMAN,sp|A0A075B6P5|KV228_HUMAN,sp|A0A0A0MRZ7|KVD26_HUMAN" 9 1302.6092 999 66813 15197 2 1302.608187 652.3119 Immunoglobulin kappa variable 2-29 OS=Homo sapiens OX=9606 GN=IGKV2-29 PE=3 SV=2 5.84 2720.5 - 5.10E+07 - - - -0.7746 - 2.777 0.64 - 404.5 1 2 0 -0.001 13 0 0 0 7.27E+09 0.00E+00 - - - 6.3891 0.9999 221125_WJC_METTL3_EV_vs_WT_F05.15198.15198.3 2.29E-06 16/60 K.TGQPMINLYTDRETGK.L "sp|P35637|FUS_HUMAN,tr|H3BPE7|H3BPE7_HUMAN" 2 1822.8883 1.24 66814 15198 3 1822.88739 608.6367 RNA-binding protein FUS OS=Homo sapiens OX=9606 GN=FUS PE=1 SV=1 5.73 2720.6 - 5.58E+06 - - - -0.5255 - 3.13 0.542 - 364.2 1 2 1 -0.001 16 0 0 0 1.33E+08 1.07E+08 - - - 7.5102 0.9998 221125_WJC_METTL3_EV_vs_WT_F05.15200.15200.2 6.26E-06 22-Nov R.GQPIYIQFSNHK.E "sp|P26599|PTBP1_HUMAN,tr|A0A6Q8PEX4|A0A6Q8PEX4_HUMAN,tr|A0A0U1RRM4|A0A0U1RRM4_HUMAN,tr|A6NLN1|A6NLN1_HUMAN,tr|K7EKJ7|K7EKJ7_HUMAN,tr|K7ES59|K7ES59_HUMAN,tr|A0A7I2V4H6|A0A7I2V4H6_HUMAN,tr|A0A7I2V621|A0A7I2V621_HUMAN" 8 1430.7306 0.95 66816 15200 2 1430.731504 716.3726 Polypyrimidine tract-binding protein 1 OS=Homo sapiens OX=9606 GN=PTBP1 PE=1 SV=1 8.6 2720.7 - 1.56E+06 - - - 0.5976 - 2.197 0.481 - 331.6 1 2 0 0.0009 12 0 0 0 7.57E+07 7.97E+07 - - - 4.6644 0.9999 221125_WJC_METTL3_EV_vs_WT_F05.15201.15201.3 8.32E-06 13/32 R.VVHIMDFQR[166.11].G "sp|P43243|MATR3_HUMAN,tr|D6RE02|D6RE02_HUMAN,tr|B3KM87|B3KM87_HUMAN,tr|A8MXP9|A8MXP9_HUMAN,tr|D6RAY2|D6RAY2_HUMAN,tr|D6R991|D6R991_HUMAN,tr|A0A0R4J2E8|A0A0R4J2E8_HUMAN,tr|D6RAM9|D6RAM9_HUMAN,tr|D6RIA2|D6RIA2_HUMAN,tr|H0Y8T4|H0Y8T4_HUMAN,tr|D6REM6|D6REM6_HUMAN,tr|D6RBI2|D6RBI2_HUMAN" 12 1153.5942 1.17 66817 15201 3 1153.592464 385.5387 Matrin-3 OS=Homo sapiens OX=9606 GN=MATR3 PE=1 SV=2 6.71 2720.9 - 1.05E+06 - - - -1.478 - 2.087 0.473 - 333.9 1 2 0 -0.0017 9 0 0 0 4.93E+07 4.20E+07 - - - 6.0303 0.9928 221125_WJC_METTL3_EV_vs_WT_F05.15203.15203.2 0.226 22-Oct R.MSVEADINGLRR.V "sp|P02533|K1C14_HUMAN,sp|P08727|K1C19_HUMAN,tr|C9JM50|C9JM50_HUMAN,tr|K7EMS3|K7EMS3_HUMAN" 4 1359.6929 8.13 66819 15203 2 1359.690145 680.8537 "Keratin, type I cytoskeletal 14 OS=Homo sapiens OX=9606 GN=KRT14 PE=1 SV=4" 5.82 2721.1 - 873996 - - - -2.0137 - 1.482 0.18 - 95.5 1 2 0 -0.0027 12 0 0 0 1.04E+07 1.28E+06 - - - 1.4047 1 221125_WJC_METTL3_EV_vs_WT_F05.15204.15204.3 8.14E-10 18/60 K.ALLSHDSGSDHLAFVR[166.11].A "sp|Q7L2E3|DHX30_HUMAN,tr|H7BXY3|H7BXY3_HUMAN" 2 1733.8725 9.04 66820 15204 3 1733.867199 578.9648 ATP-dependent RNA helicase DHX30 OS=Homo sapiens OX=9606 GN=DHX30 PE=1 SV=1 5.98 2721.2 - 616749 - - - -3.0296 - 3.253 0.558 - 437.7 1 2 0 -0.0053 16 0 0 0 7.67E+07 8.48E+06 - - - 7.7863 1 221125_WJC_METTL3_EV_vs_WT_F05.15207.15207.3 1.59E-09 16/64 K.FYDANYDGKEYDPVEAR.Q "sp|Q15555|MARE2_HUMAN,tr|K7ERD8|K7ERD8_HUMAN,tr|K7EL66|K7EL66_HUMAN" 3 2050.8909 0.96 66823 15207 3 2050.891633 684.6376 Microtubule-associated protein RP\EB family member 2 OS=Homo sapiens OX=9606 GN=MAPRE2 PE=1 SV=1 4.11 2721.6 - 359441 - - - 0.3813 - 2.805 0.724 - 268.4 1 2 1 0.0008 17 0 0 0 3.33E+06 3.46E+06 - - - 9.2173 0.9998 221125_WJC_METTL3_EV_vs_WT_F05.15209.15209.2 8.96E-09 14/26 K.SAADELQANLPPTK.Q "sp|Q9BY49|PECR_HUMAN,tr|B4DJS2|B4DJS2_HUMAN" 2 1453.7413 1.61 66825 15209 2 1453.739104 727.8779 Peroxisomal trans-2-enoyl-CoA reductase OS=Homo sapiens OX=9606 GN=PECR PE=1 SV=2 4.37 2721.9 - 310716 - - - -1.492 - 2.61 0.495 - 439.3 1 2 0 -0.0022 14 0 0 0 1.19E+07 7.41E+06 - - - 5.1038 0.9997 221125_WJC_METTL3_EV_vs_WT_F05.15214.15214.3 0.000129 16/68 R.HIISATSLSTSPTELGSR.N sp|Q5JSZ5|PRC2B_HUMAN 1 1855.964 1.58 66828 15214 3 1855.96981 619.6619 Protein PRRC2B OS=Homo sapiens OX=9606 GN=PRRC2B PE=1 SV=2 6.75 2722.4 - 2.32E+06 - - - 3.1542 - 2.208 0.452 - 178.6 1 2 0 0.0059 18 0 0 0 3.51E+07 2.22E+07 - - - 5.5501 1 221125_WJC_METTL3_EV_vs_WT_F05.15215.15215.2 8.79E-12 15/32 K.LQDLDTDYGSGYPNDPK.T sp|O75792|RNH2A_HUMAN 1 1896.8378 2.79 66829 15215 2 1896.835853 949.4262 Ribonuclease H2 subunit A OS=Homo sapiens OX=9606 GN=RNASEH2A PE=1 SV=2 3.77 2722.5 - 2.22E+06 - - - -1.0011 - 2.756 0.686 - 477.5 1 2 0 -0.0019 17 0 0 0 5.32E+07 1.90E+07 - - - 6.5996 1 221125_WJC_METTL3_EV_vs_WT_F05.15216.15216.2 1.69E-06 16/32 K.LQDLDTDYGSGYPNDPK[136.11].T sp|O75792|RNH2A_HUMAN 1 1904.852 2.79 66830 15216 2 1904.84939 953.4333 Ribonuclease H2 subunit A OS=Homo sapiens OX=9606 GN=RNASEH2A PE=1 SV=2 3.77 2722.6 - 1.51E+06 - - - -1.345 - 2.964 0.67 - 578.7 1 2 0 -0.0026 17 0 0 0 5.32E+07 1.90E+07 - - - 6.6601 1 221125_WJC_METTL3_EV_vs_WT_F05.15230.15230.2 1.87E-07 13/20 R.NPEAALSPTFR[166.11].S "sp|Q86U44|MTA70_HUMAN,tr|B4E349|B4E349_HUMAN,tr|F5H6D8|F5H6D8_HUMAN,tr|B4DTN4|B4DTN4_HUMAN" 4 1211.6174 0.02 66841 15230 2 1211.61621 606.816 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 6 2724.4 - 8.36E+06 - - - -0.9879 - 2.777 0.606 - 933.5 1 2 0 -0.0012 11 0 0 0 1.38E+07 7.05E+08 - - - 6.2796 0.9999 221125_WJC_METTL3_EV_vs_WT_F05.15232.15232.3 0.043 22/48 K.R[166.11]LIDLHSPSEIVK[136.11].Q "sp|P60866|RS20_HUMAN,tr|A0A7P0S5H5|A0A7P0S5H5_HUMAN,tr|G3XAN0|G3XAN0_HUMAN" 3 1523.879 1.34 66843 15232 3 1523.874073 508.967 40S ribosomal protein S20 OS=Homo sapiens OX=9606 GN=RPS20 PE=1 SV=1 6.75 2724.6 - 940686 - - - -3.2647 - 3.418 0.46 - 564.9 1 2 0 -0.005 13 0 0 0 2.74E+07 2.04E+07 - - - 6.9995 0.9638 221125_WJC_METTL3_EV_vs_WT_F05.15233.15233.3 0.174 Oct-48 K.LHNQVNGTEWSWK[136.11].N "sp|O14980|XPO1_HUMAN,tr|A0A7I2V488|A0A7I2V488_HUMAN,tr|A0A7I2V461|A0A7I2V461_HUMAN,tr|A0A7I2V2H0|A0A7I2V2H0_HUMAN,tr|A0A7I2V3N0|A0A7I2V3N0_HUMAN,tr|A0A7I2V4A3|A0A7I2V4A3_HUMAN,tr|A0A7I2V3W6|A0A7I2V3W6_HUMAN,tr|A0A7I2YQV4|A0A7I2YQV4_HUMAN,tr|A0A7I2YQX3|A0A7I2YQX3_HUMAN,tr|A0A7I2V2Y6|A0A7I2V2Y6_HUMAN,tr|A0A7I2V6B9|A0A7I2V6B9_HUMAN,tr|A0A7I2V3P3|A0A7I2V3P3_HUMAN,tr|A0A7I2V2S3|A0A7I2V2S3_HUMAN" 13 1605.7779 0.74 66844 15233 3 1605.772798 536.2666 Exportin-1 OS=Homo sapiens OX=9606 GN=XPO1 PE=1 SV=1 6.75 2724.8 - 683483 - - - -3.2022 - 1.767 0.163 - 104.4 1 2 0 -0.0051 13 0 0 0 7.22E+06 9.78E+06 - - - 1.8994 0.9956 221125_WJC_METTL3_EV_vs_WT_F05.15234.15234.3 0.008 13/64 K.TSILAVSDVSSSK[136.11]PSIK[136.11].A sp|Q14966|ZN638_HUMAN 1 1733.9746 0.57 66845 15234 3 1733.976969 578.9988 Zinc finger protein 638 OS=Homo sapiens OX=9606 GN=ZNF638 PE=1 SV=2 8.26 2724.9 - 530927 - - - 1.3772 - 1.944 0.205 - 156.3 1 2 0 0.0024 17 0 0 0 1.03E+07 1.80E+07 - - - 2.5042 1 221125_WJC_METTL3_EV_vs_WT_F05.15238.15238.2 7.15E-07 14/20 K.QQHVIETLIGK.K "sp|P48643|TCPE_HUMAN,tr|E9PCA1|E9PCA1_HUMAN,tr|B7ZAR1|B7ZAR1_HUMAN,tr|E7ENZ3|E7ENZ3_HUMAN" 4 1264.7139 0.65 66847 15238 2 1264.712065 633.3642 T-complex protein 1 subunit epsilon OS=Homo sapiens OX=9606 GN=CCT5 PE=1 SV=1 6.75 2725.4 - 8.59E+06 - - - -1.4794 - 2.511 0.575 - 692.4 1 2 0 -0.0019 11 0 0 0 1.87E+08 2.87E+08 - - - 5.778 1 221125_WJC_METTL3_EV_vs_WT_F05.15240.15240.3 0.00109 17/48 K.RLIDLHSPSEIVK.Q "sp|P60866|RS20_HUMAN,tr|A0A7P0S5H5|A0A7P0S5H5_HUMAN,tr|G3XAN0|G3XAN0_HUMAN" 3 1505.8566 1.34 66849 15240 3 1505.855256 502.9595 40S ribosomal protein S20 OS=Homo sapiens OX=9606 GN=RPS20 PE=1 SV=1 6.75 2725.6 - 1.36E+06 - - - -0.8779 - 2.829 0.418 - 407.7 1 2 0 -0.0013 13 0 0 0 2.74E+07 2.04E+07 - - - 6.0195 0.9275 221125_WJC_METTL3_EV_vs_WT_F05.15241.15241.3 0.0128 Sep-36 Q.PIYIQFSNHK[136.11].E "sp|P26599|PTBP1_HUMAN,tr|A0A6Q8PEX4|A0A6Q8PEX4_HUMAN,tr|A0A0U1RRM4|A0A0U1RRM4_HUMAN,tr|A6NLN1|A6NLN1_HUMAN,tr|K7EKJ7|K7EKJ7_HUMAN,tr|K7ES59|K7ES59_HUMAN,tr|A0A7I2V4H6|A0A7I2V4H6_HUMAN,tr|A0A7I2V621|A0A7I2V621_HUMAN" 8 1253.6648 1.14 66850 15241 3 1253.661704 418.8955 Polypyrimidine tract-binding protein 1 OS=Homo sapiens OX=9606 GN=PTBP1 PE=1 SV=1 9.01 2725.7 - 958123 - - - -2.4751 - 1.76 0.364 - 127.7 1 1 0 -0.0031 10 0 0 0 9.80E+06 8.58E+06 - - - 4.2483 0.9998 221125_WJC_METTL3_EV_vs_WT_F05.15247.15247.3 0.000223 15/56 K.KVPQVSTPTLVEVSR.N "sp|P02768|ALBU_HUMAN,tr|A0A087WWT3|A0A087WWT3_HUMAN,tr|B7WNR0|B7WNR0_HUMAN,tr|H0YA55|H0YA55_HUMAN,tr|A0A0C4DGB6|A0A0C4DGB6_HUMAN,tr|D6RHD5|D6RHD5_HUMAN,tr|C9JKR2|C9JKR2_HUMAN" 7 1638.9305 503.83 66854 15247 3 1638.923556 547.3174 Albumin OS=Homo sapiens OX=9606 GN=ALB PE=1 SV=2 8.75 2726.5 - 887541 - - - -4.2192 - 2.913 0.499 - 360.9 1 2 0 -0.0069 15 0 0 0 5.20E+08 1.03E+06 - - - 6.8913 0.9999 221125_WJC_METTL3_EV_vs_WT_F05.15248.15248.3 1.31E-06 13/48 R.EQDLPLAEAVR[166.11]PK[136.11].T sp|Q96A49|SYAP1_HUMAN 1 1482.8161 1.38 66855 15248 3 1482.813245 495.2793 Synapse-associated protein 1 OS=Homo sapiens OX=9606 GN=SYAP1 PE=1 SV=1 4.68 2726.6 - 2.42E+06 - - - -1.9342 - 2.194 0.514 - 272.1 1 2 0 -0.0029 13 0 0 0 6.96E+07 5.03E+07 - - - 6.4001 1 221125_WJC_METTL3_EV_vs_WT_F05.15253.15253.3 1.02E-05 18/60 R.DLEAEHVEVEDTTLNR[166.11].C "sp|Q9H3K6|BOLA2_HUMAN,tr|A0A087WZT3|A0A087WZT3_HUMAN,tr|H3BVE0|H3BVE0_HUMAN,tr|A0A0B4J295|A0A0B4J295_HUMAN,tr|H3BTW0|H3BTW0_HUMAN,tr|H3BV85|H3BV85_HUMAN" 6 1878.8835 0.78 66858 15253 3 1878.881671 627.3018 BolA-like protein 2 OS=Homo sapiens OX=9606 GN=BOLA2 PE=1 SV=1 4.08 2727.2 - 7.51E+06 - - - -0.958 - 3.242 0.654 - 289.9 1 2 0 -0.0018 16 0 0 0 6.69E+07 8.60E+07 - - - 8.8489 1 221125_WJC_METTL3_EV_vs_WT_F05.15255.15255.3 1.81E-05 18/40 R.K[136.11]LDPELHLDIK[136.11].V "sp|Q12905|ILF2_HUMAN,tr|B4DY09|B4DY09_HUMAN" 2 1335.7733 1.23 66860 15255 3 1335.771264 446.265 Interleukin enhancer-binding factor 2 OS=Homo sapiens OX=9606 GN=ILF2 PE=1 SV=2 5.38 2727.4 - 3.51E+06 - - - -1.5257 - 3.023 0.538 - 458.1 1 2 0 -0.002 11 0 0 0 7.37E+07 5.99E+07 - - - 7.6803 0.9989 221125_WJC_METTL3_EV_vs_WT_F05.15263.15263.3 0.00169 13/44 K.EKEPEYTLLTER.G "sp|O95793|STAU1_HUMAN,tr|Q5JW30|Q5JW30_HUMAN" 2 1506.7566 1.93 66866 15263 3 1506.754548 503.2595 Double-stranded RNA-binding protein Staufen homolog 1 OS=Homo sapiens OX=9606 GN=STAU1 PE=1 SV=2 4.49 2728.3 - 3.55E+06 - - - -1.3546 - 2.212 0.34 - 301.2 1 2 1 -0.002 12 0 0 0 5.15E+07 2.67E+07 - - - 4.5307 0.9999 221125_WJC_METTL3_EV_vs_WT_F05.15264.15264.3 0.00217 24/80 R.VTGEADVEFATHEDAVAAMSK[136.11].D "sp|P31943|HNRH1_HUMAN,tr|H0YBD7|H0YBD7_HUMAN,tr|H0YB39|H0YB39_HUMAN,tr|H0YBG7|H0YBG7_HUMAN,tr|E9PCY7|E9PCY7_HUMAN,tr|G8JLB6|G8JLB6_HUMAN" 6 2185.0089 1.32 66867 15264 3 2184.99987 729.3436 Heterogeneous nuclear ribonucleoprotein H OS=Homo sapiens OX=9606 GN=HNRNPH1 PE=1 SV=4 4.17 2728.4 - 1.32E+06 - - - -4.1162 - 3.964 0.541 - 339.6 1 2 0 -0.009 21 0 0 0 1.58E+07 1.20E+07 - - - 7.871 1 221125_WJC_METTL3_EV_vs_WT_F05.15265.15265.3 5.38E-08 15/56 R.TGFSTSPESPYTHWK.Q "sp|Q99873|ANM1_HUMAN,tr|E9PKG1|E9PKG1_HUMAN" 2 1723.7842 1.94 66868 15265 3 1723.785839 575.602 Protein arginine N-methyltransferase 1 OS=Homo sapiens OX=9606 GN=PRMT1 PE=1 SV=3 6.41 2728.5 - 1.83E+06 - - - 0.9502 - 3.35 0.524 - 217.3 1 2 0 0.0016 15 0 0 0 1.73E+08 8.91E+07 - - - 7.5363 1 221125_WJC_METTL3_EV_vs_WT_F05.15266.15266.3 3.61E-11 24/80 R.VTGEADVEFATHEDAVAAMSK.D "sp|P31943|HNRH1_HUMAN,tr|H0YBD7|H0YBD7_HUMAN,tr|H0YB39|H0YB39_HUMAN,tr|H0YBG7|H0YBG7_HUMAN,tr|E9PCY7|E9PCY7_HUMAN,tr|G8JLB6|G8JLB6_HUMAN" 6 2176.9947 1.32 66869 15266 3 2176.997441 726.6722 Heterogeneous nuclear ribonucleoprotein H OS=Homo sapiens OX=9606 GN=HNRNPH1 PE=1 SV=4 4.17 2728.6 - 1.16E+06 - - - 1.2756 - 4.82 0.684 - 642.4 1 2 0 0.0028 21 0 0 0 1.58E+07 1.20E+07 - - - 9.9358 1 221125_WJC_METTL3_EV_vs_WT_F05.15267.15267.3 2.23E-11 21/48 R.C[160.03]PGESSHIC[160.03]DFIR.K "sp|P50897|PPT1_HUMAN,tr|Q5T0S4|Q5T0S4_HUMAN,tr|A0A286YFL6|A0A286YFL6_HUMAN,tr|A0A2C9F2P4|A0A2C9F2P4_HUMAN,tr|A0A286YFL8|A0A286YFL8_HUMAN,tr|A0A286YFF7|A0A286YFF7_HUMAN,tr|A0A286YFE3|A0A286YFE3_HUMAN" 7 1576.6762 2.56 66870 15267 3 1576.674837 526.566 Palmitoyl-protein thioesterase 1 OS=Homo sapiens OX=9606 GN=PPT1 PE=1 SV=1 5.32 2728.8 - 1.08E+06 - - - -0.8943 - 3.747 0.674 - 772.7 1 2 0 -0.0014 13 0 0 0 1.82E+07 7.11E+06 - - - 9.6355 0.9952 221125_WJC_METTL3_EV_vs_WT_F05.15270.15270.2 0.00081 22-Sep K.EKEPEYTLLTER.G "sp|O95793|STAU1_HUMAN,tr|Q5JW30|Q5JW30_HUMAN" 2 1506.7566 2.86 66873 15270 2 1506.75984 754.3856 Double-stranded RNA-binding protein Staufen homolog 1 OS=Homo sapiens OX=9606 GN=STAU1 PE=1 SV=2 4.49 2729.2 - 407212 - - - 2.1576 - 2.035 0.463 - 235.8 1 2 1 0.0033 12 0 0 0 5.15E+06 1.80E+06 - - - 4.3291 0.9999 221125_WJC_METTL3_EV_vs_WT_F05.15272.15272.3 7.11E-07 18/60 K.TGQPMINLYTDR[166.11]ETGK[136.11].L "sp|P35637|FUS_HUMAN,tr|H3BPE7|H3BPE7_HUMAN" 2 1840.9108 1.24 66874 15272 3 1840.912828 614.6442 RNA-binding protein FUS OS=Homo sapiens OX=9606 GN=FUS PE=1 SV=1 5.73 2729.4 - 1.14E+06 - - - 1.0919 - 3.387 0.526 - 543.1 1 2 1 0.002 16 0 0 0 1.33E+08 1.07E+08 - - - 7.534 0.9996 221125_WJC_METTL3_EV_vs_WT_F05.15273.15273.3 0.0002 13/36 R.NNR[166.11]FPNLQLR[166.11].D "sp|Q8TB72|PUM2_HUMAN,tr|A0A0C4DG68|A0A0C4DG68_HUMAN" 2 1290.706 1.22 66875 15273 3 1290.704554 431.2426 Pumilio homolog 2 OS=Homo sapiens OX=9606 GN=PUM2 PE=1 SV=2 12 2729.5 - 1.28E+06 - - - -1.1149 - 2.522 0.373 - 305.8 1 2 1 -0.0014 10 0 0 0 4.09E+07 3.36E+07 - - - 5.3997 0.9998 221125_WJC_METTL3_EV_vs_WT_F05.15277.15277.2 0.00425 28-Nov K.TNGLPVQNGIDADVK.D "sp|Q14671|PUM1_HUMAN,tr|Q5T1Z8|Q5T1Z8_HUMAN,tr|H0YEH2|H0YEH2_HUMAN,tr|Q5T1Z4|Q5T1Z4_HUMAN" 4 1539.7893 3.67 66879 15277 2 1539.788772 770.9019 Pumilio homolog 1 OS=Homo sapiens OX=9606 GN=PUM1 PE=1 SV=3 4.21 2730 - 528577 - - - -0.3338 - 1.999 0.452 - 239 1 2 0 -0.0005 15 0 0 0 1.13E+07 3.07E+06 - - - 4.0822 1 221125_WJC_METTL3_EV_vs_WT_F05.15278.15278.2 1.57E-11 16/38 R.FSSC[160.03]GGGGGSFGAGGGFGSR.S sp|P04264|K2C1_HUMAN 1 1764.7274 999 66880 15278 2 1764.720045 883.371 "Keratin, type II cytoskeletal 1 OS=Homo sapiens OX=9606 GN=KRT1 PE=1 SV=6" 8.25 2730.1 - 521800 - - - -4.1853 - 3.524 0.807 - 796.4 1 2 0 -0.0074 20 0 0 0 1.10E+07 0.00E+00 - - - 8.096 0.9177 221125_WJC_METTL3_EV_vs_WT_F05.15279.15279.3 0.229 Aug-48 R.FSGSGSGTDFTLK.L "sp|A2NJV5|KV229_HUMAN,sp|A0A087WW87|KV240_HUMAN,sp|P06310|KV230_HUMAN,sp|A0A075B6S2|KVD29_HUMAN,sp|P01614|KVD40_HUMAN,sp|P01615|KVD28_HUMAN,sp|A0A075B6S6|KVD30_HUMAN,sp|A0A075B6P5|KV228_HUMAN,sp|A0A0A0MRZ7|KVD26_HUMAN" 9 1302.6092 999 66881 15279 3 1302.610898 435.2103 Immunoglobulin kappa variable 2-29 OS=Homo sapiens OX=9606 GN=IGKV2-29 PE=3 SV=2 5.84 2730.3 - 481998 - - - 1.3066 - 1.39 0.114 - 45.4 1 2 0 0.0017 13 0 0 0 9.44E+06 0.00E+00 - - - 0.7034 0.9998 221125_WJC_METTL3_EV_vs_WT_F05.15280.15280.2 6.50E-09 30-Dec K.C[160.03]TLC[160.03]SQPGATIGC[160.03]EIK[136.11].A "sp|Q8IWS0|PHF6_HUMAN,tr|Q5JRC6|Q5JRC6_HUMAN,tr|A0A0D9SGE8|A0A0D9SGE8_HUMAN" 3 1801.8252 0.78 66882 15280 2 1801.821205 901.9199 PHD finger protein 6 OS=Homo sapiens OX=9606 GN=PHF6 PE=1 SV=1 5.98 2730.4 - 447402 - - - -2.2322 - 2.518 0.542 - 322.8 1 2 0 -0.004 16 0 0 0 4.36E+06 5.57E+06 - - - 5.3133 0.819 221125_WJC_METTL3_EV_vs_WT_F05.15281.15281.3 0.0354 Oct-52 K.SQIHDIVLVGGSTR[166.11].L "sp|P11142|HSP7C_HUMAN,tr|E9PNE6|E9PNE6_HUMAN,tr|A8K7Q2|A8K7Q2_HUMAN,tr|E9PKE3|E9PKE3_HUMAN,tr|E9PN89|E9PN89_HUMAN" 5 1490.8081 7 66883 15281 3 1490.811028 497.9433 Heat shock cognate 71 kDa protein OS=Homo sapiens OX=9606 GN=HSPA8 PE=1 SV=1 6.46 2730.5 - 396732 - - - 1.9902 - 1.722 0.04 - 121.5 1 2 0 0.003 14 0 0 0 3.66E+07 5.23E+06 - - - 0.4295 1 221125_WJC_METTL3_EV_vs_WT_F05.15284.15284.3 0.0011 15/56 R.TGFSTSPESPYTHWK[136.11].Q "sp|Q99873|ANM1_HUMAN,tr|E9PKG1|E9PKG1_HUMAN" 2 1731.7984 1.97 66884 15284 3 1731.799309 578.2734 Protein arginine N-methyltransferase 1 OS=Homo sapiens OX=9606 GN=PRMT1 PE=1 SV=3 6.41 2731 - 5.23E+06 - - - 0.5243 - 3.246 0.506 - 202.6 1 2 0 0.0009 15 0 0 0 1.73E+08 8.77E+07 - - - 7.2535 0.8878 221125_WJC_METTL3_EV_vs_WT_F05.15285.15285.4 0.202 Dec-96 K.SIVIRPLEPQPAPHLAR.E "sp|Q15029|U5S1_HUMAN,tr|K7EP67|K7EP67_HUMAN" 2 1893.0949 0.29 66885 15285 4 1893.095838 474.281 116 kDa U5 small nuclear ribonucleoprotein component OS=Homo sapiens OX=9606 GN=EFTUD2 PE=1 SV=1 9.34 2731 - 2.11E+06 - - - 0.5214 - 1.602 0.11 - 75.6 1 2 0 0.001 17 0 0 0 9.28E+07 3.18E+08 - - - 0.3468 0.9999 221125_WJC_METTL3_EV_vs_WT_F05.15287.15287.3 2.91E-05 Dec-40 K.NMSVHLSPC[160.03]FR.D "sp|P62280|RS11_HUMAN,tr|M0R1H5|M0R1H5_HUMAN,tr|M0QZC5|M0QZC5_HUMAN" 3 1346.6224 0.66 66887 15287 3 1346.622805 449.8814 40S ribosomal protein S11 OS=Homo sapiens OX=9606 GN=RPS11 PE=1 SV=3 8.26 2731.1 - 1.44E+06 - - - 0.3297 - 2.357 0.422 - 269.6 1 2 0 0.0004 11 0 0 0 1.11E+07 1.68E+07 - - - 5.6805 0.8837 221125_WJC_METTL3_EV_vs_WT_F05.15290.15290.3 0.528 Oct-56 R.VELNK[136.11]PSDSVGK[136.11]DVF.- "sp|Q9GZT9|EGLN1_HUMAN,tr|A0A590UJK7|A0A590UJK7_HUMAN" 2 1648.8643 0.4 66890 15290 3 1648.864914 550.6287 Egl nine homolog 1 OS=Homo sapiens OX=9606 GN=EGLN1 PE=1 SV=1 4.56 2731.5 - 1.20E+06 - - - 0.3712 - 1.617 0.126 - 64.1 1 2 1 0.0006 15 0 0 0 3.42E+06 8.48E+06 - - - 1.1986 1 221125_WJC_METTL3_EV_vs_WT_F05.15291.15291.4 4.87E-06 16/72 K.R[166.11]LIDLHSPSEIVK[136.11].Q "sp|P60866|RS20_HUMAN,tr|A0A7P0S5H5|A0A7P0S5H5_HUMAN,tr|G3XAN0|G3XAN0_HUMAN" 3 1523.879 0.001 66891 15291 4 1523.877791 381.977 40S ribosomal protein S20 OS=Homo sapiens OX=9606 GN=RPS20 PE=1 SV=1 6.75 2731.6 - 942261 - - - -0.8249 - 2.576 0.496 - 297 1 2 0 -0.0013 13 0 0 0 0.00E+00 1.26E+07 - - - 3.8937 0.9974 221125_WJC_METTL3_EV_vs_WT_F05.15292.15292.3 1.50E-06 14/56 R.SEADSDKNATILELR.S sp|P15924|DESP_HUMAN 1 1660.8268 4.77 66892 15292 3 1661.827869 554.6162 Desmoplakin OS=Homo sapiens OX=9606 GN=DSP PE=1 SV=3 4.32 2731.7 - 907944 - - - 602.757 - 2.713 0.584 - 314.9 1 2 1 1.0011 15 0 0 0 1.33E+07 2.78E+06 - - - 7.378 0.9999 221125_WJC_METTL3_EV_vs_WT_F05.15300.15300.2 0.000537 13/24 K.DLQDELAGNSEQR[166.11].K sp|Q9UQE7|SMC3_HUMAN 1 1483.6778 1.09 66900 15300 2 1483.677122 742.8462 Structural maintenance of chromosomes protein 3 OS=Homo sapiens OX=9606 GN=SMC3 PE=1 SV=2 3.92 2732.8 - 318961 - - - -0.4806 - 2.532 0.499 - 691.5 1 2 0 -0.0007 13 0 0 0 1.04E+07 9.52E+06 - - - 5.1107 0.9991 221125_WJC_METTL3_EV_vs_WT_F05.15305.15305.3 0.0069 Aug-44 R.GQPIYIQFSNHK.E "sp|P26599|PTBP1_HUMAN,tr|A0A6Q8PEX4|A0A6Q8PEX4_HUMAN,tr|A0A0U1RRM4|A0A0U1RRM4_HUMAN,tr|A6NLN1|A6NLN1_HUMAN,tr|K7EKJ7|K7EKJ7_HUMAN,tr|K7ES59|K7ES59_HUMAN,tr|A0A7I2V4H6|A0A7I2V4H6_HUMAN,tr|A0A7I2V621|A0A7I2V621_HUMAN" 8 1430.7306 0.96 66904 15305 3 1430.729457 477.9175 Polypyrimidine tract-binding protein 1 OS=Homo sapiens OX=9606 GN=PTBP1 PE=1 SV=1 8.6 2733.4 - 2.47E+06 - - - -0.8331 - 1.577 0.324 - 79.6 1 2 0 -0.0012 12 0 0 0 8.14E+08 8.45E+08 - - - 3.4146 1 221125_WJC_METTL3_EV_vs_WT_F05.15306.15306.3 1.88E-07 17/40 R.KLDPELHLDIK.V "sp|Q12905|ILF2_HUMAN,tr|B4DY09|B4DY09_HUMAN" 2 1319.7449 1.23 66905 15306 3 1319.744494 440.9222 Interleukin enhancer-binding factor 2 OS=Homo sapiens OX=9606 GN=ILF2 PE=1 SV=2 5.38 2733.4 - 5.76E+06 - - - -0.3092 - 2.91 0.558 - 475 1 2 0 -0.0004 11 0 0 0 7.36E+07 5.99E+07 - - - 7.7955 0.9999 221125_WJC_METTL3_EV_vs_WT_F05.15307.15307.3 8.10E-05 18/48 K.DRLLASTLVHSVK.K "sp|Q9NYF8|BCLF1_HUMAN,tr|E9PKI6|E9PKI6_HUMAN,tr|A0A1W2PQ43|A0A1W2PQ43_HUMAN,tr|E9PK91|E9PK91_HUMAN,tr|E9PJA7|E9PJA7_HUMAN,tr|E9PK09|E9PK09_HUMAN,tr|E9PQN2|E9PQN2_HUMAN" 7 1437.8304 2.15 66906 15307 3 1437.830944 480.2841 Bcl-2-associated transcription factor 1 OS=Homo sapiens OX=9606 GN=BCLAF1 PE=1 SV=2 8.75 2733.4 - 7.40E+06 - - - 0.4041 - 3.287 0.464 - 491.6 1 2 1 0.0006 13 0 0 0 3.30E+08 1.54E+08 - - - 6.9394 1 221125_WJC_METTL3_EV_vs_WT_F05.15308.15308.3 8.39E-05 20/48 K.DR[166.11]LLASTLVHSVK[136.11].K "sp|Q9NYF8|BCLF1_HUMAN,tr|E9PKI6|E9PKI6_HUMAN,tr|A0A1W2PQ43|A0A1W2PQ43_HUMAN,tr|E9PK91|E9PK91_HUMAN,tr|E9PJA7|E9PJA7_HUMAN,tr|E9PK09|E9PK09_HUMAN,tr|E9PQN2|E9PQN2_HUMAN" 7 1455.8528 2.15 66907 15308 3 1455.853293 486.2916 Bcl-2-associated transcription factor 1 OS=Homo sapiens OX=9606 GN=BCLAF1 PE=1 SV=2 8.75 2733.5 - 4.50E+06 - - - 0.316 - 4.061 0.538 - 1107.6 1 2 1 0.0005 13 0 0 0 3.30E+08 1.54E+08 - - - 8.3377 0.9999 221125_WJC_METTL3_EV_vs_WT_F05.15310.15310.3 0.023 13/40 K.NMSVHLSPC[160.03]FR[166.11].D "sp|P62280|RS11_HUMAN,tr|M0R1H5|M0R1H5_HUMAN,tr|M0QZC5|M0QZC5_HUMAN" 3 1356.6306 0.66 66909 15310 3 1356.629765 453.2175 40S ribosomal protein S11 OS=Homo sapiens OX=9606 GN=RPS11 PE=1 SV=3 8.26 2733.6 - 1.97E+06 - - - -0.6383 - 2.332 0.366 - 290.7 1 2 0 -0.0009 11 0 0 0 1.12E+07 1.70E+07 - - - 5.0257 1 221125_WJC_METTL3_EV_vs_WT_F05.15311.15311.2 2.66E-06 20-Dec R.NPEAALSPTFR.S "sp|Q86U44|MTA70_HUMAN,tr|B4E349|B4E349_HUMAN,tr|F5H6D8|F5H6D8_HUMAN,tr|B4DTN4|B4DTN4_HUMAN" 4 1201.6091 0.02 66910 15311 2 1201.609696 601.8118 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 6 2733.7 - 1.33E+06 - - - 0.4652 - 2.667 0.546 - 823 1 2 0 0.0006 11 0 0 0 1.38E+07 7.00E+08 - - - 5.7273 0.9999 221125_WJC_METTL3_EV_vs_WT_F05.15312.15312.2 5.47E-05 13/28 R.TGFSTSPESPYTHWK.Q "sp|Q99873|ANM1_HUMAN,tr|E9PKG1|E9PKG1_HUMAN" 2 1723.7842 2.12 66911 15312 2 1723.783233 862.8994 Protein arginine N-methyltransferase 1 OS=Homo sapiens OX=9606 GN=PRMT1 PE=1 SV=3 6.41 2733.9 - 803194 - - - -0.5616 - 3.036 0.51 - 402.5 1 2 0 -0.001 15 0 0 0 6.17E+06 2.92E+06 - - - 5.5379 0.9997 221125_WJC_METTL3_EV_vs_WT_F05.15315.15315.2 3.31E-05 13/26 K.QPAENVNQYLTDPK[136.11].F "sp|P22314|UBA1_HUMAN,tr|Q5JRR6|Q5JRR6_HUMAN" 2 1623.7984 0.8 66914 15315 2 1623.799222 812.9065 Ubiquitin-like modifier-activating enzyme 1 OS=Homo sapiens OX=9606 GN=UBA1 PE=1 SV=3 4.37 2734.2 - 657785 - - - 0.5056 - 1.817 0.44 - 305.1 1 2 0 0.0008 14 0 0 0 4.98E+06 6.19E+06 - - - 3.7892 1 221125_WJC_METTL3_EV_vs_WT_F05.15316.15316.2 0.000127 14/24 K.DLQDELAGNSEQR.K sp|Q9UQE7|SMC3_HUMAN 1 1473.6696 1.24 66915 15316 2 1473.670562 737.8421 Structural maintenance of chromosomes protein 3 OS=Homo sapiens OX=9606 GN=SMC3 PE=1 SV=2 3.92 2734.3 - 594307 - - - 0.6765 - 2.929 0.606 - 787.7 1 2 0 0.001 13 0 0 0 1.18E+07 9.52E+06 - - - 6.2748 1 221125_WJC_METTL3_EV_vs_WT_F05.15319.15319.2 0.000351 16/30 K.C[160.03]TLC[160.03]SQPGATIGC[160.03]EIK.A "sp|Q8IWS0|PHF6_HUMAN,tr|Q5JRC6|Q5JRC6_HUMAN,tr|A0A0D9SGE8|A0A0D9SGE8_HUMAN" 3 1793.811 0.78 66918 15319 2 1793.810415 897.9128 PHD finger protein 6 OS=Homo sapiens OX=9606 GN=PHF6 PE=1 SV=1 5.98 2734.7 - 457492 - - - -0.3412 - 2.807 0.668 - 505.3 1 2 0 -0.0006 16 0 0 0 4.36E+06 5.57E+06 - - - 6.5122 0.9998 221125_WJC_METTL3_EV_vs_WT_F05.15322.15322.3 0.0519 Nov-60 K.C[160.03]TLC[160.03]SQPGATIGC[160.03]EIK.A "sp|Q8IWS0|PHF6_HUMAN,tr|Q5JRC6|Q5JRC6_HUMAN,tr|A0A0D9SGE8|A0A0D9SGE8_HUMAN" 3 1793.811 2.31 66921 15322 3 1793.811587 598.9443 PHD finger protein 6 OS=Homo sapiens OX=9606 GN=PHF6 PE=1 SV=1 5.98 2735.1 - 359080 - - - 0.3122 - 2.089 0.372 - 144.5 1 2 0 0.0006 16 0 0 0 5.28E+06 2.29E+06 - - - 4.5775 1 221125_WJC_METTL3_EV_vs_WT_F05.15323.15323.2 1.31E-10 13/28 R.TGFSTSPESPYTHWK[136.11].Q "sp|Q99873|ANM1_HUMAN,tr|E9PKG1|E9PKG1_HUMAN" 2 1731.7984 2.12 66922 15323 2 1731.799195 866.9065 Protein arginine N-methyltransferase 1 OS=Homo sapiens OX=9606 GN=PRMT1 PE=1 SV=3 6.41 2735.3 - 352923 - - - 0.4585 - 2.957 0.657 - 445.6 1 2 0 0.0008 15 0 0 0 6.17E+06 2.92E+06 - - - 6.5588 1 221125_WJC_METTL3_EV_vs_WT_F05.15328.15328.2 3.36E-07 20-Dec R.TNAENEFVTIK.K sp|P04264|K2C1_HUMAN 1 1264.6299 197.33 66926 15328 2 1264.630453 633.3222 "Keratin, type II cytoskeletal 1 OS=Homo sapiens OX=9606 GN=KRT1 PE=1 SV=6" 4.53 2735.8 - 5.05E+06 - - - 0.412 - 2.61 0.589 - 627 1 2 0 0.0005 11 0 0 0 8.23E+07 4.17E+05 - - - 5.9865 1 221125_WJC_METTL3_EV_vs_WT_F05.15330.15330.2 1.51E-10 20/34 Y.SYGSGLGVGGGFSSSSGR.A "sp|P04259|K2C6B_HUMAN,sp|P02538|K2C6A_HUMAN" 2 1617.7383 999 66928 15330 2 1617.733773 809.8764 "Keratin, type II cytoskeletal 6B OS=Homo sapiens OX=9606 GN=KRT6B PE=1 SV=5" 8.46 2735.9 - 1.78E+06 - - - -2.8064 - 3.727 0.596 - 771.7 1 1 0 -0.0045 18 0 0 0 1.12E+08 0.00E+00 - - - 6.6761 0.9997 221125_WJC_METTL3_EV_vs_WT_F05.15331.15331.3 0.00957 13/52 R.LGYFSVDPDSHQGK[136.11].L "sp|P47897|SYQ_HUMAN,tr|B4DDN1|B4DDN1_HUMAN,tr|A0A0U1RR79|A0A0U1RR79_HUMAN,tr|A0A1B0GVU9|A0A1B0GVU9_HUMAN" 4 1556.7351 1.46 66929 15331 3 1556.740139 519.919 Glutamine--tRNA ligase OS=Homo sapiens OX=9606 GN=QARS1 PE=1 SV=1 5.21 2736 - 1.39E+06 - - - 3.2549 - 2.262 0.43 - 129.3 1 2 0 0.0051 14 0 0 0 3.35E+07 2.30E+07 - - - 5.5019 1 221125_WJC_METTL3_EV_vs_WT_F05.15332.15332.3 2.31E-12 24/64 R.VR[166.11]PC[160.03]VVYGGADIGQQIR[166.11].D "sp|O00571|DDX3X_HUMAN,sp|O15523|DDX3Y_HUMAN,tr|A0A2R8YFR4|A0A2R8YFR4_HUMAN,tr|A0A2R8YCW1|A0A2R8YCW1_HUMAN,tr|A0A2R8YDH3|A0A2R8YDH3_HUMAN,tr|A0A2R8YDT5|A0A2R8YDT5_HUMAN,tr|A0A2R8Y645|A0A2R8Y645_HUMAN,tr|A0A2R8YF78|A0A2R8YF78_HUMAN,tr|A0A0D9SFB3|A0A0D9SFB3_HUMAN,tr|A0A2R8YFS5|A0A2R8YFS5_HUMAN,tr|A0A0D9SF53|A0A0D9SF53_HUMAN,tr|A0A2R8Y5G6|A0A2R8Y5G6_HUMAN,tr|A0A2R8Y7T2|A0A2R8Y7T2_HUMAN,tr|A0A0D9SG12|A0A0D9SG12_HUMAN,tr|F6S8Q4|F6S8Q4_HUMAN,tr|A0A2U3TZJ9|A0A2U3TZJ9_HUMAN,tr|A0A2R8Y4A4|A0A2R8Y4A4_HUMAN" 17 1906.995 1.11 66930 15332 3 1906.995344 636.6723 ATP-dependent RNA helicase DDX3X OS=Homo sapiens OX=9606 GN=DDX3X PE=1 SV=3 8.19 2736.1 - 1.14E+06 - - - 0.1589 - 4.174 0.663 - 842.2 1 2 0 0.0003 17 0 0 0 9.19E+07 8.26E+07 - - - 9.5415 1 221125_WJC_METTL3_EV_vs_WT_F05.15333.15333.3 9.25E-07 Aug-56 K.FC[160.03]FTPHTEEGC[160.03]LSER[166.11].A "sp|P49327|FAS_HUMAN,tr|A0A0U1RQF0|A0A0U1RQF0_HUMAN" 2 1878.7904 0.67 66931 15333 3 1878.792022 627.2708 Fatty acid synthase OS=Homo sapiens OX=9606 GN=FASN PE=1 SV=3 4.75 2736.2 - 1.05E+06 - - - 0.8426 - 2.331 0.562 - 57.2 1 2 0 0.0016 15 0 0 0 5.21E+06 7.77E+06 - - - 7.0136 0.8382 221125_WJC_METTL3_EV_vs_WT_F05.15337.15337.4 0.418 Jul-72 R.INFDK[136.11]YHPGYFGK[136.11].V "sp|P46776|RL27A_HUMAN,tr|E9PLL6|E9PLL6_HUMAN" 2 1600.8009 1.02 66935 15337 4 1600.800792 401.2075 60S ribosomal protein L27a OS=Homo sapiens OX=9606 GN=RPL27A PE=1 SV=2 8.44 2736.7 - 280109 - - - -0.0762 - 1.267 0.153 - 29.5 1 2 1 -0.0001 13 0 0 0 1.42E+06 1.39E+06 - - - 0.6454 1 221125_WJC_METTL3_EV_vs_WT_F05.15338.15338.2 1.55E-09 Dec-32 R.ISIGGGSC[160.03]AISGGYGSR.A "sp|P48668|K2C6C_HUMAN,sp|P04259|K2C6B_HUMAN,sp|P02538|K2C6A_HUMAN" 3 1597.7519 999 66936 15338 2 1597.747017 799.8832 "Keratin, type II cytoskeletal 6C OS=Homo sapiens OX=9606 GN=KRT6C PE=1 SV=3" 8.22 2736.8 - 247819 - - - -3.028 - 2.637 0.653 - 415 1 2 0 -0.0048 17 0 0 0 2.26E+06 0.00E+00 - - - 6.2464 0.9993 221125_WJC_METTL3_EV_vs_WT_F05.15341.15341.3 0.069 Oct-40 K.KQPSVLVTFPK.E "sp|O75179|ANR17_HUMAN,tr|H0YM23|H0YM23_HUMAN" 2 1242.7336 3.37 66939 15341 3 1242.733693 415.2518 Ankyrin repeat domain-containing protein 17 OS=Homo sapiens OX=9606 GN=ANKRD17 PE=1 SV=3 10 2737.2 - 159470 - - - 0.0676 - 1.742 0.312 - 124 1 2 0 0.0001 11 0 0 0 1.45E+06 4.30E+05 - - - 3.5952 0.9997 221125_WJC_METTL3_EV_vs_WT_F05.15343.15343.3 8.77E-05 Dec-44 K.EK[136.11]EPEYTLLTER[166.11].G "sp|O95793|STAU1_HUMAN,tr|Q5JW30|Q5JW30_HUMAN" 2 1524.7791 2.39 66940 15343 3 1524.780833 509.267 Double-stranded RNA-binding protein Staufen homolog 1 OS=Homo sapiens OX=9606 GN=STAU1 PE=1 SV=2 4.49 2737.4 - 2.42E+06 - - - 1.1634 - 2.201 0.46 - 228.3 1 2 1 0.0018 12 0 0 0 5.02E+07 2.10E+07 - - - 5.8548 1 221125_WJC_METTL3_EV_vs_WT_F05.15345.15345.3 1.05E-10 16/64 R.VRPC[160.03]VVYGGADIGQQIR.D "sp|O00571|DDX3X_HUMAN,sp|O15523|DDX3Y_HUMAN,tr|A0A2R8YFR4|A0A2R8YFR4_HUMAN,tr|A0A2R8YCW1|A0A2R8YCW1_HUMAN,tr|A0A2R8YDH3|A0A2R8YDH3_HUMAN,tr|A0A2R8YDT5|A0A2R8YDT5_HUMAN,tr|A0A2R8Y645|A0A2R8Y645_HUMAN,tr|A0A2R8YF78|A0A2R8YF78_HUMAN,tr|A0A0D9SFB3|A0A0D9SFB3_HUMAN,tr|A0A2R8YFS5|A0A2R8YFS5_HUMAN,tr|A0A0D9SF53|A0A0D9SF53_HUMAN,tr|A0A2R8Y5G6|A0A2R8Y5G6_HUMAN,tr|A0A2R8Y7T2|A0A2R8Y7T2_HUMAN,tr|A0A0D9SG12|A0A0D9SG12_HUMAN,tr|F6S8Q4|F6S8Q4_HUMAN,tr|A0A2U3TZJ9|A0A2U3TZJ9_HUMAN,tr|A0A2R8Y4A4|A0A2R8Y4A4_HUMAN" 17 1886.9785 1.11 66941 15345 3 1886.979844 630.0001 ATP-dependent RNA helicase DDX3X OS=Homo sapiens OX=9606 GN=DDX3X PE=1 SV=3 8.19 2737.7 - 4.14E+06 - - - 0.7117 - 3.798 0.59 - 302.7 1 2 0 0.0013 17 0 0 0 9.19E+07 8.26E+07 - - - 8.4888 0.9727 221125_WJC_METTL3_EV_vs_WT_F05.15347.15347.2 0.000902 14-Sep A.STLVHSVK.K "sp|Q9NYF8|BCLF1_HUMAN,tr|E9PKI6|E9PKI6_HUMAN,tr|A0A1W2PQ43|A0A1W2PQ43_HUMAN,tr|E9PK91|E9PK91_HUMAN,tr|E9PJA7|E9PJA7_HUMAN,tr|E9PK09|E9PK09_HUMAN,tr|E9PQN2|E9PQN2_HUMAN" 7 869.4971 2.3 66943 15347 2 869.497291 435.7558 Bcl-2-associated transcription factor 1 OS=Homo sapiens OX=9606 GN=BCLAF1 PE=1 SV=2 8.49 2737.9 - 1.33E+06 - - - 0.2576 - 1.737 0.327 - 344.5 1 1 0 0.0002 8 0 0 0 1.32E+07 5.73E+06 - - - 3.1214 1 221125_WJC_METTL3_EV_vs_WT_F05.15349.15349.2 1.21E-11 18/38 F.GGFGGGAGGGDGGILTANEK.S sp|P35527|K1C9_HUMAN 1 1690.7911 624.7 66945 15349 2 1690.792472 846.4028 "Keratin, type I cytoskeletal 9 OS=Homo sapiens OX=9606 GN=KRT9 PE=1 SV=3" 4.37 2738.1 - 1.12E+06 - - - 0.8251 - 4.037 0.725 - 817.6 1 1 0 0.0014 20 0 0 0 5.58E+07 8.94E+04 - - - 7.8263 0.9998 221125_WJC_METTL3_EV_vs_WT_F05.15350.15350.2 9.17E-06 22-Oct R.NQSFC[160.03]PTVNLDK[136.11].L "sp|P46776|RL27A_HUMAN,tr|E9PLL6|E9PLL6_HUMAN,tr|E9PJD9|E9PJD9_HUMAN" 3 1429.6751 1.05 66946 15350 2 1429.672422 715.8448 60S ribosomal protein L27a OS=Homo sapiens OX=9606 GN=RPL27A PE=1 SV=2 5.83 2738.2 - 994977 - - - -1.8836 - 2.209 0.565 - 340.9 1 2 0 -0.0027 12 0 0 0 7.81E+07 7.47E+07 - - - 5.2986 0.9977 221125_WJC_METTL3_EV_vs_WT_F05.15352.15352.2 0.000292 14/24 K.DRLLASTLVHSVK.K "sp|Q9NYF8|BCLF1_HUMAN,tr|E9PKI6|E9PKI6_HUMAN,tr|A0A1W2PQ43|A0A1W2PQ43_HUMAN,tr|E9PK91|E9PK91_HUMAN,tr|E9PJA7|E9PJA7_HUMAN,tr|E9PK09|E9PK09_HUMAN,tr|E9PQN2|E9PQN2_HUMAN" 7 1437.8304 2.5 66948 15352 2 1437.831271 719.9225 Bcl-2-associated transcription factor 1 OS=Homo sapiens OX=9606 GN=BCLAF1 PE=1 SV=2 8.75 2738.4 - 791389 - - - 0.6315 - 2.193 0.425 - 405.3 1 2 1 0.0009 13 0 0 0 1.06E+07 4.24E+06 - - - 4.1952 0.9997 221125_WJC_METTL3_EV_vs_WT_F05.15354.15354.2 2.20E-06 26-Dec K.SAADELQANLPPTK[136.11].Q "sp|Q9BY49|PECR_HUMAN,tr|B4DJS2|B4DJS2_HUMAN" 2 1461.7555 1.82 66950 15354 2 1461.752196 731.885 Peroxisomal trans-2-enoyl-CoA reductase OS=Homo sapiens OX=9606 GN=PECR PE=1 SV=2 4.37 2738.7 - 468454 - - - -2.2418 - 1.969 0.545 - 251.5 1 2 0 -0.0033 14 0 0 0 1.09E+07 5.97E+06 - - - 4.7656 1 221125_WJC_METTL3_EV_vs_WT_F05.15356.15356.3 8.56E-07 13/64 K.IPYSDVNIGTGVAHPPR.W "sp|Q9UKM7|MA1B1_HUMAN,tr|A0A804HK28|A0A804HK28_HUMAN,tr|H0YG20|H0YG20_HUMAN,tr|A0A804HKS1|A0A804HKS1_HUMAN,tr|H0YGV7|H0YGV7_HUMAN,tr|A0A804HL65|A0A804HL65_HUMAN,tr|A0A804HIP1|A0A804HIP1_HUMAN,tr|A0A804HK01|A0A804HK01_HUMAN,tr|A0A804HJ23|A0A804HJ23_HUMAN,tr|A0A804HHU1|A0A804HHU1_HUMAN,tr|A0A804HK86|A0A804HK86_HUMAN,tr|A0A804HL61|A0A804HL61_HUMAN,tr|A0A804HJ66|A0A804HJ66_HUMAN,tr|H0YGQ1|H0YGQ1_HUMAN,tr|H0YI64|H0YI64_HUMAN,tr|A0A804HJW0|A0A804HJW0_HUMAN" 16 1791.9268 2.79 66952 15356 3 1791.927275 598.3162 "Endoplasmic reticulum mannosyl-oligosaccharide 1,2-alpha-mannosidase OS=Homo sapiens OX=9606 GN=MAN1B1 PE=1 SV=2" 6.74 2739 - 373546 - - - 0.2751 - 2.435 0.464 - 184 1 2 0 0.0005 17 0 0 0 3.79E+06 1.36E+06 - - - 5.9613 0.9999 221125_WJC_METTL3_EV_vs_WT_F05.15368.15368.2 1.09E-06 13/22 R.NQSFC[160.03]PTVNLDK.L "sp|P46776|RL27A_HUMAN,tr|E9PLL6|E9PLL6_HUMAN,tr|E9PJD9|E9PJD9_HUMAN" 3 1421.6609 1.06 66962 15368 2 1421.661681 711.8377 60S ribosomal protein L27a OS=Homo sapiens OX=9606 GN=RPL27A PE=1 SV=2 5.83 2740.4 - 3.19E+06 - - - 0.5388 - 2.419 0.566 - 734.8 1 2 0 0.0008 12 0 0 0 7.89E+07 7.47E+07 - - - 5.5455 0.9863 221125_WJC_METTL3_EV_vs_WT_F05.15370.15370.2 0.00647 16-Sep L.ASTLVHSVK.K "sp|Q9NYF8|BCLF1_HUMAN,tr|E9PKI6|E9PKI6_HUMAN,tr|A0A1W2PQ43|A0A1W2PQ43_HUMAN,tr|E9PK91|E9PK91_HUMAN,tr|E9PJA7|E9PJA7_HUMAN,tr|E9PK09|E9PK09_HUMAN,tr|E9PQN2|E9PQN2_HUMAN" 7 940.5342 1.03 66964 15370 2 940.534479 471.2744 Bcl-2-associated transcription factor 1 OS=Homo sapiens OX=9606 GN=BCLAF1 PE=1 SV=2 8.8 2740.6 - 1.41E+06 - - - 0.3168 - 1.965 0.399 - 306.4 1 1 0 0.0003 9 0 0 0 1.28E+07 1.25E+07 - - - 3.9422 0.9988 221125_WJC_METTL3_EV_vs_WT_F05.15377.15377.3 5.21E-05 13/68 R.LGQSDPAPLQHQMDIYQK[136.11].R "sp|P29401|TKT_HUMAN,tr|E9PFF2|E9PFF2_HUMAN,tr|A0A0B4J1R6|A0A0B4J1R6_HUMAN" 3 2076.019 2.17 66971 15377 3 2076.00638 693.0136 Transketolase OS=Homo sapiens OX=9606 GN=TKT PE=1 SV=3 5.21 2741.5 - 252466 - - - -6.0669 - 2.638 0.481 - 149.7 1 2 0 -0.0126 18 0 0 0 4.27E+06 1.97E+06 - - - 6.3146 0.9999 221125_WJC_METTL3_EV_vs_WT_F05.15387.15387.3 3.06E-09 18/60 R.VSNFK[136.11]PGVYAVSVTGR[166.11].L "sp|P63272|SPT4H_HUMAN,tr|D3DTZ5|D3DTZ5_HUMAN,tr|J3QSB9|J3QSB9_HUMAN" 3 1697.922 1.86 66979 15387 3 1697.914535 566.9813 Transcription elongation factor SPT4 OS=Homo sapiens OX=9606 GN=SUPT4H1 PE=1 SV=1 9.99 2742.6 - 752417 - - - -4.3818 - 3.25 0.553 - 347.5 1 2 0 -0.0074 16 0 0 0 3.38E+07 1.81E+07 - - - 7.7276 1 221125_WJC_METTL3_EV_vs_WT_F05.15388.15388.3 2.04E-06 Dec-48 R.GSNPHLQTFTFTR[166.11].V "sp|Q9BSJ8|ESYT1_HUMAN,tr|F8VZB1|F8VZB1_HUMAN" 2 1514.7505 6.99 66980 15388 3 1514.750615 505.9241 Extended synaptotagmin-1 OS=Homo sapiens OX=9606 GN=ESYT1 PE=1 SV=1 9.76 2742.6 - 647159 - - - 0.0456 - 2.427 0.54 - 224.2 1 2 0 0.0001 13 0 0 0 6.90E+07 9.88E+06 - - - 6.9644 0.9999 221125_WJC_METTL3_EV_vs_WT_F05.15389.15389.2 9.11E-06 24-Dec R.EQDLPLAEAVR[166.11]PK[136.11].T sp|Q96A49|SYAP1_HUMAN 1 1482.8161 3.26 66981 15389 2 1482.817676 742.4153 Synapse-associated protein 1 OS=Homo sapiens OX=9606 GN=SYAP1 PE=1 SV=1 4.68 2742.8 - 499969 - - - 1.0541 - 2.277 0.565 - 365.2 1 2 0 0.0016 13 0 0 0 9.88E+07 3.03E+07 - - - 5.3255 0.9937 221125_WJC_METTL3_EV_vs_WT_F05.15392.15392.3 0.136 Oct-60 K.C[160.03]TLC[160.03]SQPGATIGC[160.03]EIK[136.11].A "sp|Q8IWS0|PHF6_HUMAN,tr|Q5JRC6|Q5JRC6_HUMAN,tr|A0A0D9SGE8|A0A0D9SGE8_HUMAN" 3 1801.8252 2.02 66984 15392 3 1801.827082 601.6157 PHD finger protein 6 OS=Homo sapiens OX=9606 GN=PHF6 PE=1 SV=1 5.98 2743.2 - 318954 - - - 1.0295 - 1.286 0.267 - 37.1 1 2 0 0.0019 16 0 0 0 7.10E+06 3.51E+06 - - - 2.1617 1 221125_WJC_METTL3_EV_vs_WT_F05.15393.15393.2 2.79E-08 15/34 R.TIAATPIQTLPQSQSTPK[136.11].R "sp|P14859|PO2F1_HUMAN,tr|A0A0C4DG88|A0A0C4DG88_HUMAN" 2 1889.0349 2.11 66985 15393 2 1889.040298 945.5247 "POU domain, class 2, transcription factor 1 OS=Homo sapiens OX=9606 GN=POU2F1 PE=1 SV=2" 8.41 2743.3 - 309225 - - - 2.8348 - 3.389 0.589 - 541.3 1 2 0 0.0054 18 0 0 0 4.25E+08 2.02E+08 - - - 6.3904 1 221125_WJC_METTL3_EV_vs_WT_F05.15398.15398.2 0.000206 16/34 R.TIAATPIQTLPQSQSTPK.R "sp|P14859|PO2F1_HUMAN,tr|A0A0C4DG88|A0A0C4DG88_HUMAN" 2 1881.0207 2.11 66988 15398 2 1881.019051 941.5176 "POU domain, class 2, transcription factor 1 OS=Homo sapiens OX=9606 GN=POU2F1 PE=1 SV=2" 8.41 2743.9 - 1.72E+06 - - - -0.8995 - 3.275 0.551 - 509.3 1 2 0 -0.0017 18 0 0 0 4.25E+08 2.02E+08 - - - 6.0268 0.9999 221125_WJC_METTL3_EV_vs_WT_F05.15399.15399.3 0.000231 15/52 K.AQIHDLVLVGGSTR[166.11].L "sp|P0DMV8|HS71A_HUMAN,sp|P0DMV9|HS71B_HUMAN,tr|V9GZ37|V9GZ37_HUMAN,tr|A0A0G2JIW1|A0A0G2JIW1_HUMAN" 4 1474.8131 0.34 66989 15399 3 1474.812686 492.6117 Heat shock 70 kDa protein 1A OS=Homo sapiens OX=9606 GN=HSPA1A PE=1 SV=1 6.79 2743.9 - 1.56E+06 - - - -0.3119 - 2.603 0.398 - 244.5 1 2 0 -0.0005 14 0 0 0 1.12E+09 3.34E+09 - - - 5.5195 1 221125_WJC_METTL3_EV_vs_WT_F05.15405.15405.3 5.16E-09 19/68 R.TIAATPIQTLPQSQSTPK.R "sp|P14859|PO2F1_HUMAN,tr|A0A0C4DG88|A0A0C4DG88_HUMAN" 2 1881.0207 2.13 66993 15405 3 1881.019414 628.0142 "POU domain, class 2, transcription factor 1 OS=Homo sapiens OX=9606 GN=POU2F1 PE=1 SV=2" 8.41 2744.7 - 4.63E+06 - - - -0.7065 - 3.343 0.622 - 296.7 1 2 0 -0.0013 18 0 0 0 6.01E+08 2.83E+08 - - - 8.4795 0.9999 221125_WJC_METTL3_EV_vs_WT_F05.15406.15406.3 0.000549 17/48 K.QLQDIATLADQRR.A sp|O95373|IPO7_HUMAN 1 1526.8165 2.21 66994 15406 3 1526.819947 509.9461 Importin-7 OS=Homo sapiens OX=9606 GN=IPO7 PE=1 SV=1 5.96 2744.8 - 997309 - - - 2.255 - 2.485 0.445 - 520.1 1 2 0 0.0034 13 0 0 0 9.16E+06 4.14E+06 - - - 5.9684 0.9998 221125_WJC_METTL3_EV_vs_WT_F05.15407.15407.2 0.00138 14/26 K.TGQEVVFVAEPDNK.N sp|P04844|RPN2_HUMAN 1 1531.7518 1.12 66995 15407 2 1531.750337 766.8832 Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit 2 OS=Homo sapiens OX=9606 GN=RPN2 PE=1 SV=3 4.14 2744.9 - 1.07E+06 - - - -0.9799 - 3.053 0.394 - 555.4 1 2 0 -0.0015 14 0 0 0 1.38E+07 1.24E+07 - - - 4.7515 0.994 221125_WJC_METTL3_EV_vs_WT_F05.15408.15408.3 0.038 Sep-44 R.GDK[136.11]VDILYNNIK[136.11].H sp|Q9Y5B9|SP16H_HUMAN 1 1406.774 1.33 66996 15408 3 1406.772551 469.932 FACT complex subunit SPT16 OS=Homo sapiens OX=9606 GN=SUPT16H PE=1 SV=1 5.96 2745.1 - 663239 - - - -1.0513 - 2.068 0.232 - 106.4 1 2 1 -0.0015 12 0 0 0 2.70E+07 2.03E+07 - - - 3.1401 0.9999 221125_WJC_METTL3_EV_vs_WT_F05.15411.15411.3 4.01E-07 Nov-48 K.YDLDFK[136.11]SPDDPSR[166.11].Y "sp|P06733|ENOA_HUMAN,tr|A0A2R8Y6G6|A0A2R8Y6G6_HUMAN" 2 1571.7223 1.25 66999 15411 3 1571.722413 524.9147 Alpha-enolase OS=Homo sapiens OX=9606 GN=ENO1 PE=1 SV=2 4.14 2745.5 - 400363 - - - 0.0897 - 2.454 0.515 - 117.2 1 2 1 0.0001 13 0 0 0 1.20E+07 9.64E+06 - - - 6.7157 1 221125_WJC_METTL3_EV_vs_WT_F05.15416.15416.3 3.63E-09 18/68 R.TIAATPIQTLPQSQSTPK[136.11].R "sp|P14859|PO2F1_HUMAN,tr|A0A0C4DG88|A0A0C4DG88_HUMAN" 2 1889.0349 2.13 67002 15416 3 1889.037186 630.6856 "POU domain, class 2, transcription factor 1 OS=Homo sapiens OX=9606 GN=POU2F1 PE=1 SV=2" 8.41 2746.1 - 4.86E+06 - - - 1.1874 - 3.206 0.608 - 227.1 1 2 0 0.0022 18 0 0 0 6.01E+08 2.83E+08 - - - 8.219 0.9961 221125_WJC_METTL3_EV_vs_WT_F05.15418.15418.4 8.32E-06 21/108 K.PSTASAVPELATDPELEK[136.11]K[136.11].L "sp|Q86U44|MTA70_HUMAN,tr|B4E349|B4E349_HUMAN,tr|F5H6D8|F5H6D8_HUMAN,tr|H0YFV6|H0YFV6_HUMAN,tr|B4DTN4|B4DTN4_HUMAN" 5 1998.0492 0 67004 15418 4 1998.046513 500.5196 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 4.41 2746.3 - 2.26E+06 - - - -1.3458 - 3.11 0.5 - 311.6 1 1 0 -0.0027 19 0 0 0 4.18E+05 1.05E+08 - - - 3.9611 0.8799 221125_WJC_METTL3_EV_vs_WT_F05.15419.15419.3 0.00717 Oct-44 R.GDKVDILYNNIK.H sp|Q9Y5B9|SP16H_HUMAN 1 1390.7456 1.33 67005 15419 3 1390.744866 464.5892 FACT complex subunit SPT16 OS=Homo sapiens OX=9606 GN=SUPT16H PE=1 SV=1 5.96 2746.4 - 1.05E+06 - - - -0.5493 - 1.908 0.076 - 184.6 1 2 1 -0.0008 12 0 0 0 2.70E+07 2.03E+07 - - - 1.1779 0.9997 221125_WJC_METTL3_EV_vs_WT_F05.15422.15422.3 0.000201 20/48 K.IR[166.11]QEEIEIEVVQR[166.11].K "sp|Q14254|FLOT2_HUMAN,tr|E7EMK3|E7EMK3_HUMAN,tr|K7EKW9|K7EKW9_HUMAN,tr|J3QLD9|J3QLD9_HUMAN" 4 1659.9059 0.97 67008 15422 3 1659.909138 554.3092 Flotillin-2 OS=Homo sapiens OX=9606 GN=FLOT2 PE=1 SV=2 4.49 2746.8 - 747310 - - - 1.9664 - 3.226 0.405 - 895.1 1 2 1 0.0033 13 0 0 0 1.40E+07 1.44E+07 - - - 6.23 1 221125_WJC_METTL3_EV_vs_WT_F05.15423.15423.3 1.10E-07 19/68 K.GPTEQLVSPEPEVHDIER[166.11].S sp|P35813|PPM1A_HUMAN 1 2040.9992 0.71 67009 15423 3 2040.99447 681.3403 Protein phosphatase 1A OS=Homo sapiens OX=9606 GN=PPM1A PE=1 SV=1 4.25 2746.9 - 741768 - - - -2.3023 - 3.537 0.547 - 448.8 1 2 0 -0.0047 18 0 0 0 1.95E+07 2.75E+07 - - - 7.7829 1 221125_WJC_METTL3_EV_vs_WT_F05.15424.15424.2 5.71E-08 15/32 K.ASEENLLSSSSVPSADR[166.11].D "sp|Q9NRA8|4ET_HUMAN,tr|B1AKL4|B1AKL4_HUMAN" 2 1757.8307 1.66 67010 15424 2 1757.828249 879.9226 Eukaryotic translation initiation factor 4E transporter OS=Homo sapiens OX=9606 GN=EIF4ENIF1 PE=1 SV=2 4.14 2747.1 - 554056 - - - -1.3983 - 2.725 0.601 - 501.3 1 2 0 -0.0025 17 0 0 0 1.79E+07 1.08E+07 - - - 5.9438 1 221125_WJC_METTL3_EV_vs_WT_F05.15429.15429.2 0.0263 14/26 K.AQIHDLVLVGGSTR[166.11].L "sp|P0DMV8|HS71A_HUMAN,sp|P0DMV9|HS71B_HUMAN,tr|V9GZ37|V9GZ37_HUMAN,tr|A0A0G2JIW1|A0A0G2JIW1_HUMAN" 4 1474.8131 0.25 67013 15429 2 1474.812557 738.4138 Heat shock 70 kDa protein 1A OS=Homo sapiens OX=9606 GN=HSPA1A PE=1 SV=1 6.79 2747.7 - 1.76E+06 - - - -0.3994 - 2.729 0.57 - 710.4 1 2 0 -0.0006 14 0 0 0 7.91E+07 3.12E+08 - - - 5.7702 0.9759 221125_WJC_METTL3_EV_vs_WT_F05.15431.15431.3 0.144 Aug-64 K.EGMQLISEK[136.11]PETEAVVK[136.11].E "sp|Q01082|SPTB2_HUMAN,tr|A0A087WUZ3|A0A087WUZ3_HUMAN" 2 1902.9943 2.73 67015 15431 3 1903.000125 635.3387 "Spectrin beta chain, non-erythrocytic 1 OS=Homo sapiens OX=9606 GN=SPTBN1 PE=1 SV=2" 4.49 2747.9 - 1.42E+06 - - - 3.0452 - 1.666 0.204 - 30.1 1 2 0 0.0058 17 0 0 0 1.10E+08 4.02E+07 - - - 2.1023 1 221125_WJC_METTL3_EV_vs_WT_F05.15432.15432.3 6.13E-07 16/56 R.YGISSMIQSQEKPDR.V "sp|P14868|SYDC_HUMAN,tr|H7C278|H7C278_HUMAN" 2 1737.8356 1.17 67016 15432 3 1737.832613 580.2858 "Aspartate--tRNA ligase, cytoplasmic OS=Homo sapiens OX=9606 GN=DARS1 PE=1 SV=2" 6.07 2748 - 928900 - - - -1.7096 - 3.514 0.548 - 272 1 2 0 -0.003 15 0 0 0 1.29E+07 1.10E+07 - - - 7.9282 0.9999 221125_WJC_METTL3_EV_vs_WT_F05.15434.15434.3 1.70E-06 15/48 K.YDLDFKSPDDPSR.Y "sp|P06733|ENOA_HUMAN,tr|A0A2R8Y6G6|A0A2R8Y6G6_HUMAN" 2 1553.6998 1.22 67018 15434 3 1553.699176 518.9072 Alpha-enolase OS=Homo sapiens OX=9606 GN=ENO1 PE=1 SV=2 4.14 2748.3 - 576573 - - - -0.4029 - 2.327 0.572 - 224.3 1 2 1 -0.0006 13 0 0 0 1.20E+07 9.84E+06 - - - 7.207 0.9999 221125_WJC_METTL3_EV_vs_WT_F05.15435.15435.3 8.69E-12 20/60 K.ILDSVGIEADDDRLNK.V sp|P05387|RLA2_HUMAN 1 1771.8952 1.3 67019 15435 3 1771.899212 591.639 60S acidic ribosomal protein P2 OS=Homo sapiens OX=9606 GN=RPLP2 PE=1 SV=1 4.04 2748.4 - 550976 - - - 2.2597 - 3.532 0.527 - 497.8 1 2 1 0.004 16 0 0 0 2.31E+08 1.78E+08 - - - 7.6522 0.9995 221125_WJC_METTL3_EV_vs_WT_F05.15437.15437.3 0.292 Oct-40 R.AVFPSIVGR[166.11]PR[166.11].Q "sp|Q6S8J3|POTEE_HUMAN,sp|P63261|ACTG_HUMAN,sp|P68133|ACTS_HUMAN,sp|P62736|ACTA_HUMAN,sp|Q9BYX7|ACTBM_HUMAN,sp|P68032|ACTC_HUMAN,sp|P60709|ACTB_HUMAN,sp|P63267|ACTH_HUMAN,sp|A5A3E0|POTEF_HUMAN,sp|P0CG38|POTEI_HUMAN,tr|A0A804GS07|A0A804GS07_HUMAN,tr|I3L3I0|I3L3I0_HUMAN,tr|G5E9R0|G5E9R0_HUMAN,tr|E7EVS6|E7EVS6_HUMAN,tr|B8ZZJ2|B8ZZJ2_HUMAN,tr|J3KT65|J3KT65_HUMAN,tr|I3L3R2|I3L3R2_HUMAN,tr|K7EM38|K7EM38_HUMAN,tr|F6QUT6|F6QUT6_HUMAN,tr|C9JTX5|C9JTX5_HUMAN,tr|A0A6Q8PH58|A0A6Q8PH58_HUMAN,tr|F6UVQ4|F6UVQ4_HUMAN,tr|F8WB63|F8WB63_HUMAN,tr|I3L1U9|I3L1U9_HUMAN,tr|A0A2R8Y793|A0A2R8Y793_HUMAN,tr|I3L4N8|I3L4N8_HUMAN,tr|C9JUM1|C9JUM1_HUMAN,tr|F8WCH0|F8WCH0_HUMAN,tr|C9JZR7|C9JZR7_HUMAN,tr|C9JFL5|C9JFL5_HUMAN,tr|A0A2R8YGF8|A0A2R8YGF8_HUMAN,tr|A6NL76|A6NL76_HUMAN" 32 1217.7148 0.99 67021 15437 3 1217.71362 406.9122 POTE ankyrin domain family member E OS=Homo sapiens OX=9606 GN=POTEE PE=2 SV=3 12 2748.7 - 334342 - - - -0.9411 - 2.103 0.289 - 131.4 1 2 0 -0.0011 11 0 0 0 2.25E+07 2.27E+07 - - - 3.8735 0.9999 221125_WJC_METTL3_EV_vs_WT_F05.15439.15439.3 0.000781 14/48 R.EQDLPLAEAVRPK.T sp|Q96A49|SYAP1_HUMAN 1 1464.7936 2.52 67022 15439 3 1464.793283 489.2718 Synapse-associated protein 1 OS=Homo sapiens OX=9606 GN=SYAP1 PE=1 SV=1 4.68 2748.9 - 2.66E+07 - - - -0.2458 - 2.189 0.463 - 349.4 1 2 0 -0.0004 13 0 0 0 1.26E+09 5.00E+08 - - - 5.826 0.9993 221125_WJC_METTL3_EV_vs_WT_F05.15441.15441.3 3.84E-05 16/60 K.ILDSVGIEADDDR[166.11]LNK[136.11].V sp|P05387|RLA2_HUMAN 1 1789.9177 1.3 67024 15441 3 1789.910426 597.6465 60S acidic ribosomal protein P2 OS=Homo sapiens OX=9606 GN=RPLP2 PE=1 SV=1 4.04 2749.1 - 1.57E+06 - - - -4.0516 - 3.007 0.51 - 265.6 1 2 1 -0.0073 16 0 0 0 2.31E+08 1.78E+08 - - - 7.0489 1 221125_WJC_METTL3_EV_vs_WT_F05.15442.15442.2 1.43E-07 18/32 K.ASEENLLSSSSVPSADR.D "sp|Q9NRA8|4ET_HUMAN,tr|B1AKL4|B1AKL4_HUMAN" 2 1747.8224 1.66 67025 15442 2 1747.825176 874.9185 Eukaryotic translation initiation factor 4E transporter OS=Homo sapiens OX=9606 GN=EIF4ENIF1 PE=1 SV=2 4.14 2749.2 - 1.09E+06 - - - 1.5671 - 2.948 0.6 - 836.8 1 2 0 0.0027 17 0 0 0 1.79E+07 1.08E+07 - - - 6.1297 1 221125_WJC_METTL3_EV_vs_WT_F05.15451.15451.2 1.63E-13 20/36 K.PSTASAVPELATDPELEK[136.11]K[136.11].L "sp|Q86U44|MTA70_HUMAN,tr|B4E349|B4E349_HUMAN,tr|F5H6D8|F5H6D8_HUMAN,tr|H0YFV6|H0YFV6_HUMAN,tr|B4DTN4|B4DTN4_HUMAN" 5 1998.0492 0.001 67032 15451 2 1998.04565 1000.0319 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 4.41 2750.4 - 3.20E+06 - - - -1.7777 - 3.645 0.673 - 797.8 1 1 0 -0.0036 19 0 0 0 0.00E+00 1.71E+08 - - - 7.1904 0.9998 221125_WJC_METTL3_EV_vs_WT_F05.15452.15452.3 9.21E-05 Oct-44 K.VLSLNFSEC[160.03]HTK.L "sp|Q9UN86|G3BP2_HUMAN,tr|A0A7I2V3E2|A0A7I2V3E2_HUMAN,tr|D6RAC7|D6RAC7_HUMAN,tr|D6RB17|D6RB17_HUMAN,tr|A0A7I2YQS2|A0A7I2YQS2_HUMAN,tr|A0A7I2YQG8|A0A7I2YQG8_HUMAN,tr|A0A7I2V572|A0A7I2V572_HUMAN,tr|D6RBR0|D6RBR0_HUMAN,tr|D6RBW8|D6RBW8_HUMAN" 9 1433.6973 1.42 67033 15452 3 1433.694545 478.9064 Ras GTPase-activating protein-binding protein 2 OS=Homo sapiens OX=9606 GN=G3BP2 PE=1 SV=2 6.71 2750.5 - 2.39E+06 - - - -1.9216 - 1.726 0.463 - 87 1 2 0 -0.0028 12 0 0 0 1.26E+08 8.89E+07 - - - 5.2141 0.9999 221125_WJC_METTL3_EV_vs_WT_F05.15453.15453.3 0.0008 Nov-44 K.VLSLNFSEC[160.03]HTK[136.11].L "sp|Q9UN86|G3BP2_HUMAN,tr|A0A7I2V3E2|A0A7I2V3E2_HUMAN,tr|D6RAC7|D6RAC7_HUMAN,tr|D6RB17|D6RB17_HUMAN,tr|A0A7I2YQS2|A0A7I2YQS2_HUMAN,tr|A0A7I2YQG8|A0A7I2YQG8_HUMAN,tr|A0A7I2V572|A0A7I2V572_HUMAN,tr|D6RBR0|D6RBR0_HUMAN,tr|D6RBW8|D6RBW8_HUMAN" 9 1441.7115 1.42 67034 15453 3 1441.710191 481.5778 Ras GTPase-activating protein-binding protein 2 OS=Homo sapiens OX=9606 GN=G3BP2 PE=1 SV=2 6.71 2750.5 - 2.35E+06 - - - -0.9079 - 2.41 0.416 - 145.9 1 2 0 -0.0013 12 0 0 0 1.26E+08 8.89E+07 - - - 5.6158 0.9964 221125_WJC_METTL3_EV_vs_WT_F05.15459.15459.3 0.00906 14/60 R.LC[160.03]PTHADSLNNLANIK.R sp|O15294|OGT1_HUMAN 1 1779.8938 0.12 67038 15459 3 1779.88673 594.3052 UDP-N-acetylglucosamine--peptide N-acetylglucosaminyltransferase 110 kDa subunit OS=Homo sapiens OX=9606 GN=OGT PE=1 SV=3 6.73 2751.3 - 893584 - - - -3.9542 - 2.054 0.312 - 211.1 1 2 0 -0.007 16 0 0 0 1.95E+07 1.58E+08 - - - 3.8634 0.999 221125_WJC_METTL3_EV_vs_WT_F05.15460.15460.2 1.78E-05 24-Nov R.ANLPQSFQVDTSK[136.11].A "sp|P21333|FLNA_HUMAN,tr|Q60FE5|Q60FE5_HUMAN" 2 1441.7293 1.09 67039 15460 2 1441.735118 721.8719 Filamin-A OS=Homo sapiens OX=9606 GN=FLNA PE=1 SV=4 5.88 2751.4 - 845669 - - - 4.0646 - 2.283 0.544 - 304.9 1 2 0 0.0059 13 0 0 0 7.31E+07 6.69E+07 - - - 5.1758 0.9999 221125_WJC_METTL3_EV_vs_WT_F05.15466.15466.3 0.000677 13/36 R.QWKPQLGFNR.D sp|Q9H0D6|XRN2_HUMAN 1 1272.6727 0.86 67043 15466 3 1272.67143 425.2315 5'-3' exoribonuclease 2 OS=Homo sapiens OX=9606 GN=XRN2 PE=1 SV=1 11 2752.1 - 1.36E+06 - - - -1.0293 - 2.17 0.372 - 278.9 1 2 0 -0.0013 10 0 0 0 1.59E+08 1.83E+08 - - - 4.9496 0.9998 221125_WJC_METTL3_EV_vs_WT_F05.15467.15467.3 0.000117 22/60 R.SRPFTVAASFQSTSVK.S "sp|Q9UHB6|LIMA1_HUMAN,tr|F8VQE1|F8VQE1_HUMAN,tr|F8VS07|F8VS07_HUMAN" 3 1711.8893 1.2 67044 15467 3 1711.880918 571.6371 LIM domain and actin-binding protein 1 OS=Homo sapiens OX=9606 GN=LIMA1 PE=1 SV=1 11 2752.3 - 1.11E+06 - - - -4.9162 - 3.793 0.501 - 695.8 1 2 0 -0.0084 16 0 0 0 1.69E+07 1.40E+07 - - - 7.544 1 221125_WJC_METTL3_EV_vs_WT_F05.15470.15470.3 1.52E-09 14/52 R.R[166.11]IGIFGQDEDVTSK[136.11].A "sp|P16615|AT2A2_HUMAN,tr|H7C5W9|H7C5W9_HUMAN" 2 1581.8118 1.49 67045 15470 3 1581.811125 528.2779 Sarcoplasmic\endoplasmic reticulum calcium ATPase 2 OS=Homo sapiens OX=9606 GN=ATP2A2 PE=1 SV=1 4.56 2752.6 - 463249 - - - -0.3989 - 2.811 0.57 - 206.3 1 2 0 -0.0006 14 0 0 0 1.67E+07 1.12E+07 - - - 7.6414 0.9543 221125_WJC_METTL3_EV_vs_WT_F05.15471.15471.3 1.39E-05 15/60 F.QALLQYADPVSAQHAK[136.11].L "sp|P26599|PTBP1_HUMAN,tr|A0A6Q8PEX4|A0A6Q8PEX4_HUMAN,tr|A0A0U1RRM4|A0A0U1RRM4_HUMAN,tr|A6NLN1|A6NLN1_HUMAN,tr|K7EKJ7|K7EKJ7_HUMAN,tr|A0A087WU68|A0A087WU68_HUMAN,tr|A0A7I2V4H6|A0A7I2V4H6_HUMAN,tr|A0A7I2V621|A0A7I2V621_HUMAN,tr|K7EK45|K7EK45_HUMAN" 9 1746.9144 0.76 67046 15471 3 1746.909082 583.3121 Polypyrimidine tract-binding protein 1 OS=Homo sapiens OX=9606 GN=PTBP1 PE=1 SV=1 6.74 2752.8 - 536730 - - - -3.0631 - 2.615 0.363 - 282.3 1 1 0 -0.0054 16 0 0 0 8.89E+06 1.16E+07 - - - 5.0521 0.9999 221125_WJC_METTL3_EV_vs_WT_F05.15473.15473.3 0.000432 Dec-40 R.AVFPSIVGRPR.Q "sp|Q6S8J3|POTEE_HUMAN,sp|P63261|ACTG_HUMAN,sp|P68133|ACTS_HUMAN,sp|P62736|ACTA_HUMAN,sp|Q9BYX7|ACTBM_HUMAN,sp|P68032|ACTC_HUMAN,sp|P60709|ACTB_HUMAN,sp|P63267|ACTH_HUMAN,sp|A5A3E0|POTEF_HUMAN,sp|P0CG38|POTEI_HUMAN,tr|A0A804GS07|A0A804GS07_HUMAN,tr|I3L3I0|I3L3I0_HUMAN,tr|G5E9R0|G5E9R0_HUMAN,tr|E7EVS6|E7EVS6_HUMAN,tr|B8ZZJ2|B8ZZJ2_HUMAN,tr|J3KT65|J3KT65_HUMAN,tr|I3L3R2|I3L3R2_HUMAN,tr|K7EM38|K7EM38_HUMAN,tr|F6QUT6|F6QUT6_HUMAN,tr|C9JTX5|C9JTX5_HUMAN,tr|A0A6Q8PH58|A0A6Q8PH58_HUMAN,tr|F6UVQ4|F6UVQ4_HUMAN,tr|F8WB63|F8WB63_HUMAN,tr|I3L1U9|I3L1U9_HUMAN,tr|A0A2R8Y793|A0A2R8Y793_HUMAN,tr|I3L4N8|I3L4N8_HUMAN,tr|C9JUM1|C9JUM1_HUMAN,tr|F8WCH0|F8WCH0_HUMAN,tr|C9JZR7|C9JZR7_HUMAN,tr|C9JFL5|C9JFL5_HUMAN,tr|A0A2R8YGF8|A0A2R8YGF8_HUMAN,tr|A6NL76|A6NL76_HUMAN" 32 1197.6982 0.99 67048 15473 3 1197.696241 400.24 POTE ankyrin domain family member E OS=Homo sapiens OX=9606 GN=POTEE PE=2 SV=3 12 2753 - 557967 - - - -1.6573 - 2.117 0.427 - 220.3 1 2 0 -0.002 11 0 0 0 2.23E+07 2.25E+07 - - - 5.4307 0.9998 221125_WJC_METTL3_EV_vs_WT_F05.15477.15477.3 8.18E-06 16/48 K.IRQEEIEIEVVQR.K "sp|Q14254|FLOT2_HUMAN,tr|E7EMK3|E7EMK3_HUMAN,tr|K7EKW9|K7EKW9_HUMAN,tr|J3QLD9|J3QLD9_HUMAN" 4 1639.8893 0.98 67050 15477 3 1639.886355 547.6371 Flotillin-2 OS=Homo sapiens OX=9606 GN=FLOT2 PE=1 SV=2 4.49 2753.6 - 912560 - - - -1.8166 - 2.969 0.445 - 458.7 1 2 1 -0.003 13 0 0 0 1.40E+07 1.42E+07 - - - 6.451 1 221125_WJC_METTL3_EV_vs_WT_F05.15478.15478.2 1.11E-05 14/24 R.FSGSGSGTDFTLK.L "sp|A2NJV5|KV229_HUMAN,sp|A0A087WW87|KV240_HUMAN,sp|P06310|KV230_HUMAN,sp|A0A075B6S2|KVD29_HUMAN,sp|P01614|KVD40_HUMAN,sp|P01615|KVD28_HUMAN,sp|A0A075B6S6|KVD30_HUMAN,sp|A0A075B6P5|KV228_HUMAN,sp|A0A0A0MRZ7|KVD26_HUMAN" 9 1302.6092 150.85 67051 15478 2 1302.607022 652.3119 Immunoglobulin kappa variable 2-29 OS=Homo sapiens OX=9606 GN=IGKV2-29 PE=3 SV=2 5.84 2753.6 - 2.66E+06 - - - -1.669 - 2.768 0.646 - 469.7 1 2 0 -0.0022 13 0 0 0 5.14E+07 3.41E+05 - - - 6.4247 0.904 221125_WJC_METTL3_EV_vs_WT_F05.15483.15483.3 0.0142 Dec-40 H.NKDEVYQILEK.G "sp|P52732|KIF11_HUMAN,tr|A0A7I2YQY4|A0A7I2YQY4_HUMAN,tr|A0A7I2V3A9|A0A7I2V3A9_HUMAN,tr|A0A7I2V3V3|A0A7I2V3V3_HUMAN" 4 1377.714 4.95 67053 15483 3 1377.710927 460.2453 Kinesin-like protein KIF11 OS=Homo sapiens OX=9606 GN=KIF11 PE=1 SV=2 4.68 2754.2 - 1.62E+06 - - - -2.2276 - 2.361 0.375 - 188.9 1 1 1 -0.0031 11 0 0 0 3.76E+07 7.60E+06 - - - 5.1605 0.9999 221125_WJC_METTL3_EV_vs_WT_F05.15485.15485.2 4.61E-05 13/24 R.ANLPQSFQVDTSK.A "sp|P21333|FLNA_HUMAN,tr|Q60FE5|Q60FE5_HUMAN" 2 1433.7151 1.09 67055 15485 2 1433.716518 717.8648 Filamin-A OS=Homo sapiens OX=9606 GN=FLNA PE=1 SV=4 5.88 2754.4 - 1.68E+06 - - - 1.0183 - 2.422 0.566 - 422.4 1 2 0 0.0015 13 0 0 0 7.31E+07 6.72E+07 - - - 5.4914 1 221125_WJC_METTL3_EV_vs_WT_F05.15487.15487.2 4.62E-07 16/30 R.GQAAVQQLQAEGLSPR.F "sp|P16152|CBR1_HUMAN,sp|O75828|CBR3_HUMAN,tr|E9PQ63|E9PQ63_HUMAN,tr|A8MTM1|A8MTM1_HUMAN" 4 1651.8642 1.35 67057 15487 2 1651.861835 826.9394 Carbonyl reductase [NADPH] 1 OS=Homo sapiens OX=9606 GN=CBR1 PE=1 SV=3 6 2754.7 - 402429 - - - -1.4208 - 3.482 0.576 - 1094.8 1 2 0 -0.0023 16 0 0 0 3.73E+07 2.77E+07 - - - 6.3619 0.9996 221125_WJC_METTL3_EV_vs_WT_F05.15489.15489.2 1.49E-06 20-Sep R.NPEAALSPTFR[166.11].S "sp|Q86U44|MTA70_HUMAN,tr|B4E349|B4E349_HUMAN,tr|F5H6D8|F5H6D8_HUMAN,tr|B4DTN4|B4DTN4_HUMAN" 4 1211.6174 0.001 67058 15489 2 1211.614864 606.816 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 6 2754.9 - 385431 - - - -2.0988 - 2.085 0.443 - 346.5 1 2 0 -0.0025 11 0 0 0 0.00E+00 1.42E+07 - - - 4.2999 0.9995 221125_WJC_METTL3_EV_vs_WT_F05.15492.15492.3 0.000196 13/40 K.TQEELKELLNK.M "sp|O60341|KDM1A_HUMAN,tr|R4GMQ1|R4GMQ1_HUMAN" 2 1343.7296 1.29 67060 15492 3 1343.726181 448.9172 Lysine-specific histone demethylase 1A OS=Homo sapiens OX=9606 GN=KDM1A PE=1 SV=2 4.78 2755.2 - 889419 - - - -2.5786 - 2.612 0.447 - 206.1 1 2 1 -0.0035 11 0 0 0 2.11E+07 1.64E+07 - - - 6.2502 0.902 221125_WJC_METTL3_EV_vs_WT_F05.15493.15493.3 1.38E-07 20/72 K.PSTASAVPELATDPELEKK.L "sp|Q86U44|MTA70_HUMAN,tr|B4E349|B4E349_HUMAN,tr|F5H6D8|F5H6D8_HUMAN,tr|H0YFV6|H0YFV6_HUMAN,tr|B4DTN4|B4DTN4_HUMAN" 5 1982.0208 0 67061 15493 3 1983.02758 661.6809 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 4.41 2755.3 - 1.78E+06 - - - 507.9553 - 3.073 0.531 - 474.5 1 1 0 1.0068 19 0 0 0 3.68E+07 1.04E+10 - - - 6.9394 0.9999 221125_WJC_METTL3_EV_vs_WT_F05.15494.15494.3 2.61E-05 20/60 R.GQAAVQQLQAEGLSPR.F "sp|P16152|CBR1_HUMAN,sp|O75828|CBR3_HUMAN,tr|E9PQ63|E9PQ63_HUMAN,tr|A8MTM1|A8MTM1_HUMAN" 4 1651.8642 1.44 67062 15494 3 1651.85857 551.6287 Carbonyl reductase [NADPH] 1 OS=Homo sapiens OX=9606 GN=CBR1 PE=1 SV=3 6 2755.5 - 977453 - - - -3.3974 - 3.558 0.527 - 727.3 1 2 0 -0.0056 16 0 0 0 5.54E+07 3.86E+07 - - - 7.6706 0.9959 221125_WJC_METTL3_EV_vs_WT_F05.15497.15497.3 0.015 Nov-40 R.QQELDNLLHEK[136.11].R "sp|Q12788|TBL3_HUMAN,tr|J3KNP2|J3KNP2_HUMAN" 2 1373.703 1.18 67063 15497 3 1373.69748 458.9083 Transducin beta-like protein 3 OS=Homo sapiens OX=9606 GN=TBL3 PE=1 SV=2 4.65 2755.8 - 1.15E+06 - - - -4.0504 - 1.769 0.328 - 178.4 1 2 0 -0.0056 11 0 0 0 2.72E+07 2.32E+07 - - - 3.8158 0.9699 221125_WJC_METTL3_EV_vs_WT_F05.15498.15498.4 0.0797 Dec-90 K.VILHLK[136.11]EDQTEYLEER[166.11].R "sp|P08238|HS90B_HUMAN,sp|Q58FF6|H90B4_HUMAN,sp|Q58FF7|H90B3_HUMAN,sp|P07900|HS90A_HUMAN,tr|G3V2J8|G3V2J8_HUMAN" 5 2032.0596 0.73 67064 15498 4 2032.055846 509.0222 Heat shock protein HSP 90-beta OS=Homo sapiens OX=9606 GN=HSP90AB1 PE=1 SV=4 4.57 2756 - 1.43E+06 - - - -1.843 - 2.205 0.213 - 128.1 1 2 1 -0.0037 16 0 0 0 3.70E+07 5.07E+07 - - - 1.3575 1 221125_WJC_METTL3_EV_vs_WT_F05.15500.15500.3 4.93E-08 18/84 K.LYHDPNVNGGTELEPVEGNPYR.R sp|P57740|NU107_HUMAN 1 2469.1561 7.7 67066 15500 3 2469.15073 824.0593 Nuclear pore complex protein Nup107 OS=Homo sapiens OX=9606 GN=NUP107 PE=1 SV=1 4.4 2756.2 - 727011 - - - -2.1615 - 3.347 0.62 - 225.2 1 2 0 -0.0053 22 0 0 0 9.23E+06 1.20E+06 - - - 8.315 0.9975 221125_WJC_METTL3_EV_vs_WT_F05.15507.15507.3 5.59E-12 22/80 Q.VVHHVVPTEPLPAPGPASVTE.- "sp|Q9BQA1|MEP50_HUMAN,tr|H0Y711|H0Y711_HUMAN" 2 2132.1266 - 67070 15507 3 2132.121333 711.7161 Methylosome protein 50 OS=Homo sapiens OX=9606 GN=WDR77 PE=1 SV=1 5.37 2757.1 - 1.56E+06 - - - -2.4726 - 3.057 0.645 - 441.9 1 1 0 -0.0053 21 0 0 0 - - - - - 8.4086 0.9997 221125_WJC_METTL3_EV_vs_WT_F05.15508.15508.4 0.000486 19/90 K.VILHLKEDQTEYLEER.R "sp|P08238|HS90B_HUMAN,sp|Q58FF6|H90B4_HUMAN,sp|Q58FF7|H90B3_HUMAN,sp|P07900|HS90A_HUMAN,tr|G3V2J8|G3V2J8_HUMAN" 5 2014.0371 0.73 67071 15508 4 2014.035686 504.5166 Heat shock protein HSP 90-beta OS=Homo sapiens OX=9606 GN=HSP90AB1 PE=1 SV=4 4.57 2757.2 - 1.06E+06 - - - -0.7125 - 2.859 0.438 - 287.1 1 2 1 -0.0014 16 0 0 0 3.70E+07 5.07E+07 - - - 3.408 1 221125_WJC_METTL3_EV_vs_WT_F05.15509.15509.3 6.54E-10 20/60 R.GQAAVQQLQAEGLSPR[166.11].F "sp|P16152|CBR1_HUMAN,sp|O75828|CBR3_HUMAN,tr|E9PQ63|E9PQ63_HUMAN,tr|A8MTM1|A8MTM1_HUMAN" 4 1661.8725 1.45 67072 15509 3 1661.871813 554.9648 Carbonyl reductase [NADPH] 1 OS=Homo sapiens OX=9606 GN=CBR1 PE=1 SV=3 6 2757.3 - 982506 - - - -0.3845 - 3.87 0.572 - 665.2 1 2 0 -0.0006 16 0 0 0 5.51E+07 3.79E+07 - - - 8.3893 0.9994 221125_WJC_METTL3_EV_vs_WT_F05.15514.15514.3 0.000259 Dec-40 K.TK[136.11]EQILEEFSK[136.11].V "sp|O60506|HNRPQ_HUMAN,tr|A0A7I2YQV8|A0A7I2YQV8_HUMAN,tr|A0A7I2YQN2|A0A7I2YQN2_HUMAN,tr|A0A7I2V5Q6|A0A7I2V5Q6_HUMAN,tr|A0A7I2V4Z0|A0A7I2V4Z0_HUMAN,tr|B7Z645|B7Z645_HUMAN,tr|A0A7I2V2F2|A0A7I2V2F2_HUMAN,tr|A0A7I2V346|A0A7I2V346_HUMAN,tr|A0A7I2V309|A0A7I2V309_HUMAN" 9 1366.7315 1.26 67075 15514 3 1366.734929 456.5844 Heterogeneous nuclear ribonucleoprotein Q OS=Homo sapiens OX=9606 GN=SYNCRIP PE=1 SV=2 4.78 2757.9 - 1.93E+06 - - - 2.5111 - 2.56 0.425 - 354.2 1 2 1 0.0034 11 0 0 0 1.17E+08 9.26E+07 - - - 5.9478 1 221125_WJC_METTL3_EV_vs_WT_F05.15516.15516.3 9.86E-05 14/44 R.DGWPAMGIHGDK.S "sp|P17844|DDX5_HUMAN,tr|A0A7I2V5F5|A0A7I2V5F5_HUMAN,tr|A0A7I2V507|A0A7I2V507_HUMAN,tr|J3KTA4|J3KTA4_HUMAN,tr|A0A0G2JLI4|A0A0G2JLI4_HUMAN,tr|A0A7I2V2S0|A0A7I2V2S0_HUMAN" 6 1282.5765 1.5 67077 15516 3 1282.575905 428.5328 Probable ATP-dependent RNA helicase DDX5 OS=Homo sapiens OX=9606 GN=DDX5 PE=1 SV=1 5.21 2758.2 - 762782 - - - -0.4296 - 2.327 0.494 - 131 1 2 0 -0.0006 12 0 0 0 2.64E+07 1.76E+07 - - - 6.3885 0.9979 221125_WJC_METTL3_EV_vs_WT_F05.15517.15517.2 0.0173 18-Sep R.QWKPQLGFNR.D sp|Q9H0D6|XRN2_HUMAN 1 1272.6727 1.24 67078 15517 2 1272.671961 637.3436 5'-3' exoribonuclease 2 OS=Homo sapiens OX=9606 GN=XRN2 PE=1 SV=1 11 2758.3 - 624859 - - - -0.6121 - 1.466 0.226 - 191.5 1 2 0 -0.0008 10 0 0 0 1.89E+07 1.52E+07 - - - 1.7778 0.9998 221125_WJC_METTL3_EV_vs_WT_F05.15519.15519.3 0.00903 Nov-40 R.LK[136.11]VGLQVVAVK[136.11].A "sp|P10809|CH60_HUMAN,tr|A0A7I2V2X6|A0A7I2V2X6_HUMAN,tr|A0A7I2YQK6|A0A7I2YQK6_HUMAN,tr|A0A7I2V599|A0A7I2V599_HUMAN,tr|A0A7I2V5M1|A0A7I2V5M1_HUMAN" 5 1168.7878 1.05 67080 15519 3 1168.785874 390.6032 "60 kDa heat shock protein, mitochondrial OS=Homo sapiens OX=9606 GN=HSPD1 PE=1 SV=2" 10 2758.6 - 275386 - - - -1.6735 - 2.115 0.512 - 125.6 1 2 1 -0.002 11 0 0 0 5.76E+06 5.51E+06 - - - 6.3757 0.9999 221125_WJC_METTL3_EV_vs_WT_F05.15523.15523.2 0.000254 16/30 R.GQAAVQQLQAEGLSPR[166.11].F "sp|P16152|CBR1_HUMAN,sp|O75828|CBR3_HUMAN,tr|E9PQ63|E9PQ63_HUMAN,tr|A8MTM1|A8MTM1_HUMAN" 4 1661.8725 1.35 67082 15523 2 1661.871273 831.9435 Carbonyl reductase [NADPH] 1 OS=Homo sapiens OX=9606 GN=CBR1 PE=1 SV=3 6 2759 - 806567 - - - -0.7094 - 3.385 0.495 - 960.2 1 2 0 -0.0012 16 0 0 0 3.73E+07 2.77E+07 - - - 5.6945 1 221125_WJC_METTL3_EV_vs_WT_F05.15524.15524.3 3.21E-05 15/56 R.SLNYC[160.03]GHIYTPISC[160.03]K[136.11].L "sp|Q93009|UBP7_HUMAN,tr|I3L2D8|I3L2D8_HUMAN,tr|A0A669KBL1|A0A669KBL1_HUMAN,tr|H3BND8|H3BND8_HUMAN" 4 1819.8477 1.05 67083 15524 3 1819.846895 607.6232 Ubiquitin carboxyl-terminal hydrolase 7 OS=Homo sapiens OX=9606 GN=USP7 PE=1 SV=2 7.79 2759.1 - 747416 - - - -0.4292 - 2.766 0.571 - 177.3 1 2 0 -0.0008 15 0 0 0 1.07E+07 1.02E+07 - - - 7.5606 0.9991 221125_WJC_METTL3_EV_vs_WT_F05.15525.15525.3 4.90E-09 16/60 K.VILHLKEDQTEYLEER.R "sp|P08238|HS90B_HUMAN,sp|Q58FF6|H90B4_HUMAN,sp|Q58FF7|H90B3_HUMAN,sp|P07900|HS90A_HUMAN,tr|G3V2J8|G3V2J8_HUMAN" 5 2014.0371 0.54 67084 15525 3 2014.026665 672.353 Heat shock protein HSP 90-beta OS=Homo sapiens OX=9606 GN=HSP90AB1 PE=1 SV=4 4.57 2759.2 - 2.71E+06 - - - -5.1916 - 3.321 0.577 - 369.1 1 2 1 -0.0105 16 0 0 0 2.36E+07 4.37E+07 - - - 8.0498 0.9999 221125_WJC_METTL3_EV_vs_WT_F05.15526.15526.3 6.47E-07 13/40 K.TQEELK[136.11]ELLNK[136.11].M "sp|O60341|KDM1A_HUMAN,tr|R4GMQ1|R4GMQ1_HUMAN" 2 1359.758 1.28 67085 15526 3 1359.759244 454.26 Lysine-specific histone demethylase 1A OS=Homo sapiens OX=9606 GN=KDM1A PE=1 SV=2 4.78 2759.3 - 1.08E+06 - - - 0.881 - 2.514 0.528 - 216.3 1 2 1 0.0012 11 0 0 0 2.09E+07 1.64E+07 - - - 7.0452 1 221125_WJC_METTL3_EV_vs_WT_F05.15527.15527.2 6.39E-05 18/30 R.VEAAQETVADYQQTIK.K "sp|Q14203|DCTN1_HUMAN,tr|A0A804CDA6|A0A804CDA6_HUMAN,tr|E7EX90|E7EX90_HUMAN,tr|A0A7P0Z4C3|A0A7P0Z4C3_HUMAN,tr|Q6AWB1|Q6AWB1_HUMAN" 5 1792.8843 2.66 67086 15527 2 1792.888001 897.4494 Dynactin subunit 1 OS=Homo sapiens OX=9606 GN=DCTN1 PE=1 SV=3 4.14 2759.4 - 715921 - - - 2.0593 - 3.851 0.499 - 1139.3 1 2 0 0.0037 16 0 0 0 1.00E+07 3.77E+06 - - - 6.0404 0.9633 221125_WJC_METTL3_EV_vs_WT_F05.15531.15531.3 1.58E-06 13/60 R.VEAAQETVADYQQTIK[136.11].K "sp|Q14203|DCTN1_HUMAN,tr|A0A804CDA6|A0A804CDA6_HUMAN,tr|E7EX90|E7EX90_HUMAN,tr|A0A7P0Z4C3|A0A7P0Z4C3_HUMAN,tr|Q6AWB1|Q6AWB1_HUMAN" 5 1800.8985 0.7 67090 15531 3 1801.910608 601.3068 Dynactin subunit 1 OS=Homo sapiens OX=9606 GN=DCTN1 PE=1 SV=3 4.14 2759.9 - 566407 - - - 561.9967 - 2.541 0.418 - 235.4 1 2 0 1.0121 16 0 0 0 1.04E+07 1.49E+07 - - - 5.3128 0.9998 221125_WJC_METTL3_EV_vs_WT_F05.15534.15534.3 0.0084 13/36 R.QWK[136.11]PQLGFNR[166.11].D sp|Q9H0D6|XRN2_HUMAN 1 1290.6952 0.86 67092 15534 3 1290.694221 431.239 5'-3' exoribonuclease 2 OS=Homo sapiens OX=9606 GN=XRN2 PE=1 SV=1 11 2760.3 - 8.86E+06 - - - -0.7663 - 2.061 0.361 - 214.5 1 2 0 -0.001 10 0 0 0 1.58E+08 1.83E+08 - - - 4.6766 0.9996 221125_WJC_METTL3_EV_vs_WT_F05.15536.15536.3 0.000402 14/60 R.VEAAQETVADYQQTIK.K "sp|Q14203|DCTN1_HUMAN,tr|A0A804CDA6|A0A804CDA6_HUMAN,tr|E7EX90|E7EX90_HUMAN,tr|A0A7P0Z4C3|A0A7P0Z4C3_HUMAN,tr|Q6AWB1|Q6AWB1_HUMAN" 5 1792.8843 0.65 67093 15536 3 1792.88073 598.6354 Dynactin subunit 1 OS=Homo sapiens OX=9606 GN=DCTN1 PE=1 SV=3 4.14 2760.6 - 967446 - - - -1.9962 - 2.141 0.353 - 311 1 2 0 -0.0036 16 0 0 0 1.04E+07 1.60E+07 - - - 4.4279 1 221125_WJC_METTL3_EV_vs_WT_F05.15537.15537.3 9.28E-08 Dec-56 R.SLNYC[160.03]GHIYTPISC[160.03]K.L "sp|Q93009|UBP7_HUMAN,tr|I3L2D8|I3L2D8_HUMAN,tr|A0A669KBL1|A0A669KBL1_HUMAN,tr|H3BND8|H3BND8_HUMAN" 4 1811.8335 1.05 67094 15537 3 1811.834006 604.9518 Ubiquitin carboxyl-terminal hydrolase 7 OS=Homo sapiens OX=9606 GN=USP7 PE=1 SV=2 7.79 2760.7 - 805250 - - - 0.2925 - 2.334 0.587 - 99.5 1 2 0 0.0005 15 0 0 0 1.07E+07 1.02E+07 - - - 7.296 1 221125_WJC_METTL3_EV_vs_WT_F05.15539.15539.2 1.75E-06 19/34 R.FGGNPGGFGNQGGFGNSR.G "sp|Q13148|TADBP_HUMAN,tr|A0A087WX29|A0A087WX29_HUMAN" 2 1725.7608 1.56 67096 15539 2 1725.75701 863.8877 TAR DNA-binding protein 43 OS=Homo sapiens OX=9606 GN=TARDBP PE=1 SV=1 9.75 2760.9 - 462180 - - - -2.1845 - 3.663 0.664 - 1159 1 2 0 -0.0038 18 0 0 0 4.23E+08 2.71E+08 - - - 7.136 1 221125_WJC_METTL3_EV_vs_WT_F05.15540.15540.2 8.50E-13 17/38 R.FSSC[160.03]GGGGGSFGAGGGFGSR.S sp|P04264|K2C1_HUMAN 1 1764.7274 999 67097 15540 2 1764.729664 883.371 "Keratin, type II cytoskeletal 1 OS=Homo sapiens OX=9606 GN=KRT1 PE=1 SV=6" 8.25 2761.1 - 459625 - - - 1.2654 - 3.733 0.783 - 913.7 1 2 0 0.0022 20 0 0 0 9.39E+06 0.00E+00 - - - 8.062 0.9995 221125_WJC_METTL3_EV_vs_WT_F05.15543.15543.3 0.00217 Sep-48 K.DGIEPMWEDEKNK.R "sp|P06730|IF4E_HUMAN,tr|H0Y8J7|H0Y8J7_HUMAN,tr|D6RBW1|D6RBW1_HUMAN" 3 1589.7032 3.48 67100 15543 3 1589.704304 530.9083 Eukaryotic translation initiation factor 4E OS=Homo sapiens OX=9606 GN=EIF4E PE=1 SV=2 4.18 2761.5 - 342326 - - - 0.7115 - 1.935 0.428 - 113.3 1 2 1 0.0011 13 0 0 0 8.00E+06 2.30E+06 - - - 5.1012 0.9994 221125_WJC_METTL3_EV_vs_WT_F05.15544.15544.2 3.98E-07 30-Oct R.VEAAQETVADYQQTIK[136.11].K "sp|Q14203|DCTN1_HUMAN,tr|A0A804CDA6|A0A804CDA6_HUMAN,tr|E7EX90|E7EX90_HUMAN,tr|A0A7P0Z4C3|A0A7P0Z4C3_HUMAN,tr|Q6AWB1|Q6AWB1_HUMAN" 5 1800.8985 2.66 67101 15544 2 1800.903177 901.4565 Dynactin subunit 1 OS=Homo sapiens OX=9606 GN=DCTN1 PE=1 SV=3 4.14 2761.6 - 321310 - - - 2.592 - 2.394 0.424 - 288.6 1 2 0 0.0047 16 0 0 0 1.00E+07 3.77E+06 - - - 4.3174 1 221125_WJC_METTL3_EV_vs_WT_F05.15547.15547.3 3.39E-11 18/60 K.VILHLK[136.11]EDQTEYLEER[166.11].R "sp|P08238|HS90B_HUMAN,sp|Q58FF6|H90B4_HUMAN,sp|Q58FF7|H90B3_HUMAN,sp|P07900|HS90A_HUMAN,tr|G3V2J8|G3V2J8_HUMAN" 5 2032.0596 0.54 67102 15547 3 2032.059558 678.3605 Heat shock protein HSP 90-beta OS=Homo sapiens OX=9606 GN=HSP90AB1 PE=1 SV=4 4.57 2762 - 3.40E+06 - - - -0.0162 - 3.391 0.674 - 382.2 1 2 1 0 16 0 0 0 2.36E+07 4.37E+07 - - - 9.1877 0.9999 221125_WJC_METTL3_EV_vs_WT_F05.15548.15548.4 1.18E-07 20/90 K.FILAPAKQEDEWDKPR.L sp|P13674|P4HA1_HUMAN 1 1941.9949 1.65 67103 15548 4 1941.99823 486.506 Prolyl 4-hydroxylase subunit alpha-1 OS=Homo sapiens OX=9606 GN=P4HA1 PE=1 SV=2 4.78 2762.1 - 1.44E+06 - - - 1.7343 - 2.828 0.567 - 209.2 1 2 1 0.0034 16 0 0 0 2.40E+07 1.46E+07 - - - 4.5264 1 221125_WJC_METTL3_EV_vs_WT_F05.15549.15549.2 1.31E-14 20/34 R.FGGNPGGFGNQGGFGNSR[166.11].G "sp|Q13148|TADBP_HUMAN,tr|A0A087WX29|A0A087WX29_HUMAN" 2 1735.7691 1.56 67104 15549 2 1735.768872 868.8918 TAR DNA-binding protein 43 OS=Homo sapiens OX=9606 GN=TARDBP PE=1 SV=1 9.75 2762.2 - 1.23E+06 - - - -0.1025 - 3.904 0.66 - 1313.2 1 2 0 -0.0002 18 0 0 0 4.23E+08 2.71E+08 - - - 7.2642 1 221125_WJC_METTL3_EV_vs_WT_F05.15550.15550.3 5.98E-07 16/68 R.FGGNPGGFGNQGGFGNSR.G "sp|Q13148|TADBP_HUMAN,tr|A0A087WX29|A0A087WX29_HUMAN" 2 1725.7608 13.08 67105 15550 3 1725.76279 576.2609 TAR DNA-binding protein 43 OS=Homo sapiens OX=9606 GN=TARDBP PE=1 SV=1 9.75 2762.2 - 814121 - - - 1.1647 - 2.813 0.466 - 192.5 1 2 0 0.002 18 0 0 0 1.72E+08 1.32E+07 - - - 6.3103 1 221125_WJC_METTL3_EV_vs_WT_F05.15551.15551.3 5.62E-07 13/52 K.IESVHFSDQFSGPK.L "sp|Q96A33|CCD47_HUMAN,tr|A0A087WYW6|A0A087WYW6_HUMAN" 2 1576.7522 1.81 67106 15551 3 1576.754315 526.5913 PAT complex subunit CCDC47 OS=Homo sapiens OX=9606 GN=CCDC47 PE=1 SV=1 5.32 2762.4 - 551682 - - - 1.3591 - 2.798 0.552 - 249.7 1 2 0 0.0021 14 0 0 0 6.88E+06 3.80E+06 - - - 7.428 1 221125_WJC_METTL3_EV_vs_WT_F05.15553.15553.2 1.71E-09 18/30 K.SELVANNVTLPAGEQR.K "sp|P42166|LAP2A_HUMAN,sp|P42167|LAP2B_HUMAN,tr|G5E972|G5E972_HUMAN" 3 1696.8744 3.99 67108 15553 2 1696.880439 849.4445 "Lamina-associated polypeptide 2, isoform alpha OS=Homo sapiens OX=9606 GN=TMPO PE=1 SV=2" 4.53 2762.6 - 507432 - - - 3.5512 - 3.347 0.684 - 1036.5 1 2 0 0.006 16 0 0 0 4.46E+07 1.12E+07 - - - 7.0612 1 221125_WJC_METTL3_EV_vs_WT_F05.15554.15554.2 1.13E-06 17/30 K.SELVANNVTLPAGEQR[166.11].K "sp|P42166|LAP2A_HUMAN,sp|P42167|LAP2B_HUMAN,tr|G5E972|G5E972_HUMAN" 3 1706.8827 3.93 67109 15554 2 1706.88476 854.4486 "Lamina-associated polypeptide 2, isoform alpha OS=Homo sapiens OX=9606 GN=TMPO PE=1 SV=2" 4.53 2762.8 - 448265 - - - 1.2168 - 3.33 0.64 - 865.2 1 2 0 0.0021 16 0 0 0 4.40E+07 1.12E+07 - - - 6.725 1 221125_WJC_METTL3_EV_vs_WT_F05.15556.15556.3 6.20E-11 16/60 K.FILAPAKQEDEWDKPR.L sp|P13674|P4HA1_HUMAN 1 1941.9949 1.6 67111 15556 3 1941.995386 648.3389 Prolyl 4-hydroxylase subunit alpha-1 OS=Homo sapiens OX=9606 GN=P4HA1 PE=1 SV=2 4.78 2763 - 431978 - - - 0.2698 - 2.958 0.641 - 304.5 1 2 1 0.0005 16 0 0 0 7.15E+06 4.47E+06 - - - 8.4691 0.9999 221125_WJC_METTL3_EV_vs_WT_F05.15558.15558.3 0.000225 Dec-60 K.SELVANNVTLPAGEQR[166.11].K "sp|P42166|LAP2A_HUMAN,sp|P42167|LAP2B_HUMAN,tr|G5E972|G5E972_HUMAN" 3 1706.8827 1.29 67113 15558 3 1706.886238 569.9682 "Lamina-associated polypeptide 2, isoform alpha OS=Homo sapiens OX=9606 GN=TMPO PE=1 SV=2" 4.53 2763.3 - 347803 - - - 2.0827 - 2.547 0.457 - 162 1 2 0 0.0036 16 0 0 0 1.75E+07 1.35E+07 - - - 6.033 0.9999 221125_WJC_METTL3_EV_vs_WT_F05.15559.15559.3 5.11E-06 19/56 R.LFQQIYSDGSDEVKR.A sp|Q9Y2Z0|SGT1_HUMAN 1 1783.8741 1.02 67114 15559 3 1783.879707 595.632 Protein SGT1 homolog OS=Homo sapiens OX=9606 GN=SUGT1 PE=1 SV=3 4.56 2763.4 - 291557 - - - 3.1555 - 3.674 0.529 - 587.8 1 2 0 0.0056 15 0 0 0 2.00E+07 1.95E+07 - - - 7.8318 0.9999 221125_WJC_METTL3_EV_vs_WT_F05.15560.15560.2 7.57E-07 Nov-34 R.VDSAATSGYEIGNPPDYR.G "sp|P24666|PPAC_HUMAN,tr|G5E9R5|G5E9R5_HUMAN" 2 1910.8646 0.99 67115 15560 2 1910.865202 956.4396 Low molecular weight phosphotyrosine protein phosphatase OS=Homo sapiens OX=9606 GN=ACP1 PE=1 SV=3 4.03 2763.6 - 201618 - - - 0.2962 - 2.217 0.609 - 233.6 1 2 0 0.0006 18 0 0 0 2.40E+07 2.42E+07 - - - 5.4963 0.9985 221125_WJC_METTL3_EV_vs_WT_F05.15561.15561.3 8.16E-05 Oct-48 R.KYEMFAQTLQQSR.G "sp|P55072|TERA_HUMAN,tr|A0A7P0T8Q5|A0A7P0T8Q5_HUMAN,tr|C9JUP7|C9JUP7_HUMAN,tr|A0A7P0TAW3|A0A7P0TAW3_HUMAN,tr|A0A7I2V540|A0A7I2V540_HUMAN,tr|A0A7P0T8A3|A0A7P0T8A3_HUMAN,tr|A0A7P0TA22|A0A7P0TA22_HUMAN" 7 1628.7981 0.91 67116 15561 3 1628.805908 543.94 Transitional endoplasmic reticulum ATPase OS=Homo sapiens OX=9606 GN=VCP PE=1 SV=4 8.59 2763.7 - 198885 - - - 4.8085 - 2.022 0.425 - 157.4 1 2 0 0.0078 13 0 0 0 2.68E+06 2.94E+06 - - - 5.1851 0.9996 221125_WJC_METTL3_EV_vs_WT_F05.15562.15562.3 0.0115 Oct-68 R.VDSAATSGYEIGNPPDYR[166.11].G "sp|P24666|PPAC_HUMAN,tr|G5E9R5|G5E9R5_HUMAN" 2 1920.8729 1.39 67117 15562 3 1920.874712 641.2982 Low molecular weight phosphotyrosine protein phosphatase OS=Homo sapiens OX=9606 GN=ACP1 PE=1 SV=3 4.03 2763.8 - 190986 - - - 0.9402 - 1.966 0.346 - 125.7 1 2 0 0.0018 18 0 0 0 5.39E+06 3.87E+06 - - - 4.0804 1 221125_WJC_METTL3_EV_vs_WT_F05.15566.15566.3 7.46E-12 20/72 K.PSTASAVPELATDPELEK[136.11]K[136.11].L "sp|Q86U44|MTA70_HUMAN,tr|B4E349|B4E349_HUMAN,tr|F5H6D8|F5H6D8_HUMAN,tr|H0YFV6|H0YFV6_HUMAN,tr|B4DTN4|B4DTN4_HUMAN" 5 1998.0492 0 67119 15566 3 1998.050702 667.0237 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 4.41 2764.3 - 2.10E+07 - - - 0.7507 - 3.693 0.663 - 471.3 1 1 0 0.0015 19 0 0 0 3.68E+07 1.04E+10 - - - 9.141 0.9999 221125_WJC_METTL3_EV_vs_WT_F05.15568.15568.3 1.06E-07 14/52 R.LQDEIQNMKEEMAR.H "sp|P08670|VIME_HUMAN,tr|B0YJC5|B0YJC5_HUMAN,tr|B0YJC4|B0YJC4_HUMAN" 3 1733.8077 1.9 67121 15568 3 1733.810197 578.9432 Vimentin OS=Homo sapiens OX=9606 GN=VIM PE=1 SV=4 4.41 2764.4 - 4.53E+06 - - - 1.4661 - 2.824 0.582 - 298.1 1 2 1 0.0025 14 0 0 0 1.18E+09 6.20E+08 - - - 7.7869 0.9999 221125_WJC_METTL3_EV_vs_WT_F05.15569.15569.3 1.88E-06 16/52 R.LQDEIQNMK[136.11]EEMAR[166.11].H "sp|P08670|VIME_HUMAN,tr|B0YJC5|B0YJC5_HUMAN,tr|B0YJC4|B0YJC4_HUMAN" 3 1751.8301 1.89 67122 15569 3 1751.833112 584.9507 Vimentin OS=Homo sapiens OX=9606 GN=VIM PE=1 SV=4 4.41 2764.4 - 3.56E+06 - - - 1.7051 - 3.116 0.564 - 457.1 1 2 1 0.003 14 0 0 0 1.17E+09 6.20E+08 - - - 7.8476 0.9998 221125_WJC_METTL3_EV_vs_WT_F05.15571.15571.3 1.02E-05 Nov-52 K.SLELIQGEPLNK[136.11]DK[136.11].L "sp|Q8IWZ3|ANKH1_HUMAN,tr|E9PDP5|E9PDP5_HUMAN" 2 1598.885 1.41 67124 15571 3 1598.886308 533.969 Ankyrin repeat and KH domain-containing protein 1 OS=Homo sapiens OX=9606 GN=ANKHD1 PE=1 SV=1 4.68 2764.7 - 459671 - - - 0.7949 - 2.228 0.467 - 86.1 1 2 1 0.0013 14 0 0 0 1.09E+07 7.74E+06 - - - 5.8752 1 221125_WJC_METTL3_EV_vs_WT_F05.15572.15572.3 1.90E-07 13/60 R.LTQYHGGSLPNVSQLR.S "sp|Q6UUV7|CRTC3_HUMAN,tr|H0YK33|H0YK33_HUMAN" 2 1768.922 1.25 67125 15572 3 1768.922389 590.648 CREB-regulated transcription coactivator 3 OS=Homo sapiens OX=9606 GN=CRTC3 PE=1 SV=2 8.75 2764.8 - 433903 - - - 0.2024 - 2.796 0.551 - 219.4 1 2 0 0.0004 16 0 0 0 1.12E+07 8.95E+06 - - - 7.3212 1 221125_WJC_METTL3_EV_vs_WT_F05.15575.15575.2 3.52E-11 15/38 R.GTPGPDSSGSLGSGEFTGVK.E "sp|Q9UBC2|EP15R_HUMAN,tr|M0R2S2|M0R2S2_HUMAN,tr|M0R165|M0R165_HUMAN" 3 1835.8537 1.56 67128 15575 2 1835.860133 918.9341 Epidermal growth factor receptor substrate 15-like 1 OS=Homo sapiens OX=9606 GN=EPS15L1 PE=1 SV=1 4.37 2765.2 - 316416 - - - 3.4839 - 3.043 0.694 - 360.8 1 2 0 0.0064 20 0 0 0 3.08E+06 1.98E+06 - - - 6.9009 0.9999 221125_WJC_METTL3_EV_vs_WT_F05.15576.15576.3 0.000254 Nov-68 R.VDSAATSGYEIGNPPDYR.G "sp|P24666|PPAC_HUMAN,tr|G5E9R5|G5E9R5_HUMAN" 2 1910.8646 1.64 67129 15576 3 1910.860065 637.9622 Low molecular weight phosphotyrosine protein phosphatase OS=Homo sapiens OX=9606 GN=ACP1 PE=1 SV=3 4.03 2765.3 - 299176 - - - -2.3921 - 2.288 0.552 - 97 1 2 0 -0.0046 18 0 0 0 1.84E+07 1.12E+07 - - - 6.754 0.9996 221125_WJC_METTL3_EV_vs_WT_F05.15577.15577.3 0.00714 Oct-36 R.SIHDALC[160.03]VIR.C "sp|P50991|TCPD_HUMAN,sp|P48643|TCPE_HUMAN,tr|E9PCA1|E9PCA1_HUMAN,tr|B7ZAR1|B7ZAR1_HUMAN,tr|E7ENZ3|E7ENZ3_HUMAN" 5 1182.6179 0.56 67130 15577 3 1182.621305 395.2133 T-complex protein 1 subunit delta OS=Homo sapiens OX=9606 GN=CCT4 PE=1 SV=4 6.46 2765.4 - 258745 - - - 2.8564 - 1.951 0.41 - 180.7 1 2 0 0.0034 10 0 0 0 2.06E+06 3.66E+06 - - - 5.062 0.9995 221125_WJC_METTL3_EV_vs_WT_F05.15578.15578.2 0.000407 13/30 R.TAAANAAAGAAENAFR[166.11].A sp|O14828|SCAM3_HUMAN 1 1485.72 1.06 67131 15578 2 1485.715547 743.8673 Secretory carrier-associated membrane protein 3 OS=Homo sapiens OX=9606 GN=SCAMP3 PE=1 SV=3 5.66 2765.6 - 248777 - - - -2.9797 - 2.558 0.506 - 336.5 1 2 0 -0.0044 16 0 0 0 2.33E+06 2.19E+06 - - - 5.0861 1 221125_WJC_METTL3_EV_vs_WT_F05.15579.15579.2 1.41E-09 14/34 R.VDSAATSGYEIGNPPDYR[166.11].G "sp|P24666|PPAC_HUMAN,tr|G5E9R5|G5E9R5_HUMAN" 2 1920.8729 0.99 67132 15579 2 1920.873582 961.4437 Low molecular weight phosphotyrosine protein phosphatase OS=Homo sapiens OX=9606 GN=ACP1 PE=1 SV=3 4.03 2765.7 - 182868 - - - 0.3519 - 3.061 0.692 - 457.3 1 2 0 0.0007 18 0 0 0 2.55E+07 2.56E+07 - - - 6.9024 0.9375 221125_WJC_METTL3_EV_vs_WT_F05.15580.15580.2 0.00649 30-Jun G.RGGGPPGEGGGQAQHR[166.11].S tr|A0A087WZ99|A0A087WZ99_HUMAN 1 1526.7326 - 67133 15580 2 1526.731014 764.3736 Hepatoma-derived growth factor-related protein 2 (Fragment) OS=Homo sapiens OX=9606 GN=HDGFL2 PE=1 SV=1 9.61 2765.8 - 165062 - - - -1.0421 - 1.36 0.36 - 67.2 1 1 0 -0.0016 16 0 0 0 - - - - - 2.4554 1 221125_WJC_METTL3_EV_vs_WT_F05.15581.15581.2 3.10E-07 Dec-38 R.GTPGPDSSGSLGSGEFTGVK[136.11].E "sp|Q9UBC2|EP15R_HUMAN,tr|M0R2S2|M0R2S2_HUMAN,tr|M0R165|M0R165_HUMAN" 3 1843.8679 1.56 67134 15581 2 1843.866283 922.9412 Epidermal growth factor receptor substrate 15-like 1 OS=Homo sapiens OX=9606 GN=EPS15L1 PE=1 SV=1 4.37 2766 - 143430 - - - -0.897 - 2.28 0.636 - 202.8 1 2 0 -0.0017 20 0 0 0 3.08E+06 1.98E+06 - - - 5.7642 1 221125_WJC_METTL3_EV_vs_WT_F05.15585.15585.3 8.05E-08 16/68 K.IFHAPNASAPSSSLSTFK[136.11].D "sp|Q9H2P0|ADNP_HUMAN,tr|A0A669KBJ7|A0A669KBJ7_HUMAN" 2 1868.9512 1.53 67136 15585 3 1868.952106 623.991 Activity-dependent neuroprotector homeobox protein OS=Homo sapiens OX=9606 GN=ADNP PE=1 SV=1 8.76 2766.4 - 1.58E+06 - - - 0.4778 - 3.088 0.449 - 385.4 1 2 0 0.0009 18 0 0 0 4.18E+07 2.72E+07 - - - 6.3533 0.9999 221125_WJC_METTL3_EV_vs_WT_F05.15587.15587.3 1.18E-08 18/68 K.IFHAPNASAPSSSLSTFK.D "sp|Q9H2P0|ADNP_HUMAN,tr|A0A669KBJ7|A0A669KBJ7_HUMAN" 2 1860.937 1.52 67138 15587 3 1860.940713 621.3196 Activity-dependent neuroprotector homeobox protein OS=Homo sapiens OX=9606 GN=ADNP PE=1 SV=1 8.76 2766.6 - 1.33E+06 - - - 1.9882 - 3.217 0.359 - 230.1 1 2 0 0.0037 18 0 0 0 4.12E+07 2.70E+07 - - - 5.451 0.982 221125_WJC_METTL3_EV_vs_WT_F05.15591.15591.3 0.227 Aug-44 R.DGWPAMGIHGDK[136.11].S "sp|P17844|DDX5_HUMAN,tr|A0A7I2V5F5|A0A7I2V5F5_HUMAN,tr|A0A7I2V507|A0A7I2V507_HUMAN,tr|J3KTA4|J3KTA4_HUMAN,tr|A0A0G2JLI4|A0A0G2JLI4_HUMAN,tr|A0A7I2V2S0|A0A7I2V2S0_HUMAN" 6 1290.5907 1.6 67142 15591 3 1290.591292 431.2042 Probable ATP-dependent RNA helicase DDX5 OS=Homo sapiens OX=9606 GN=DDX5 PE=1 SV=1 5.21 2767.1 - 821884 - - - 0.4928 - 1.433 0.197 - 38.2 4 2 0 0.0006 12 0 0 0 1.23E+07 7.71E+06 - - - 1.4548 0.9998 221125_WJC_METTL3_EV_vs_WT_F05.15598.15598.2 6.25E-08 24-Dec R.SEQEFQEQLESAR.R "sp|Q96RQ3|MCCA_HUMAN,tr|G5E9X5|G5E9X5_HUMAN,tr|E9PG35|E9PG35_HUMAN,tr|E9PHF7|E9PHF7_HUMAN,tr|F5GYT8|F5GYT8_HUMAN" 5 1579.7114 2.22 67149 15598 2 1579.714304 790.863 "Methylcrotonoyl-CoA carboxylase subunit alpha, mitochondrial OS=Homo sapiens OX=9606 GN=MCCC1 PE=1 SV=3" 4.09 2767.9 - 250863 - - - 1.8193 - 2.763 0.506 - 673.1 1 2 0 0.0029 13 0 0 0 3.68E+06 1.66E+06 - - - 5.3858 0.999 221125_WJC_METTL3_EV_vs_WT_F05.15600.15600.2 0.000237 24-Nov R.SEQEFQEQLESAR[166.11].R "sp|Q96RQ3|MCCA_HUMAN,tr|G5E9X5|G5E9X5_HUMAN,tr|E9PG35|E9PG35_HUMAN,tr|E9PHF7|E9PHF7_HUMAN,tr|F5GYT8|F5GYT8_HUMAN" 5 1589.7197 2.22 67151 15600 2 1589.713185 795.8671 "Methylcrotonoyl-CoA carboxylase subunit alpha, mitochondrial OS=Homo sapiens OX=9606 GN=MCCC1 PE=1 SV=3" 4.09 2768.2 - 203284 - - - -4.0982 - 2.478 0.533 - 447.2 1 2 0 -0.0065 13 0 0 0 3.68E+06 1.66E+06 - - - 5.3047 0.999 221125_WJC_METTL3_EV_vs_WT_F05.15604.15604.2 2.57E-06 14/26 R.LQDEIQNMK[136.11]EEMAR[166.11].H "sp|P08670|VIME_HUMAN,tr|B0YJC5|B0YJC5_HUMAN,tr|B0YJC4|B0YJC4_HUMAN" 3 1751.8301 1.4 67153 15604 2 1751.829328 876.9223 Vimentin OS=Homo sapiens OX=9606 GN=VIM PE=1 SV=4 4.41 2768.7 - 1.47E+06 - - - -0.455 - 2.962 0.521 - 834.7 1 2 1 -0.0008 14 0 0 0 4.39E+07 3.13E+07 - - - 5.6138 1 221125_WJC_METTL3_EV_vs_WT_F05.15608.15608.2 2.12E-07 30-Oct K.TVTLPENEDELESTNR.R "sp|P30876|RPB2_HUMAN,tr|C9J4M6|C9J4M6_HUMAN,tr|C9J2Y9|C9J2Y9_HUMAN" 3 1845.8592 3.45 67157 15608 2 1845.860568 923.9369 DNA-directed RNA polymerase II subunit RPB2 OS=Homo sapiens OX=9606 GN=POLR2B PE=1 SV=1 3.91 2769.1 - 439607 - - - 0.7325 - 2.262 0.66 - 206.2 1 2 0 0.0014 16 0 0 0 5.24E+06 1.52E+06 - - - 5.9221 0.9951 221125_WJC_METTL3_EV_vs_WT_F05.15610.15610.3 0.0125 Sep-64 R.VPTHTLAMVVPPQEPDR[166.11].T "sp|Q8IWZ3|ANKH1_HUMAN,tr|E9PDP5|E9PDP5_HUMAN,tr|H7C2F5|H7C2F5_HUMAN" 3 1895.9803 0.97 67159 15610 3 1895.974794 633.0007 Ankyrin repeat and KH domain-containing protein 1 OS=Homo sapiens OX=9606 GN=ANKHD1 PE=1 SV=1 5.32 2769.4 - 346609 - - - -2.8977 - 1.824 0.27 - 42.9 1 2 0 -0.0055 17 0 0 0 6.83E+06 7.06E+06 - - - 3.0671 0.9996 221125_WJC_METTL3_EV_vs_WT_F05.15611.15611.2 3.90E-07 13/26 K.SAADELQANLPPTK.Q "sp|Q9BY49|PECR_HUMAN,tr|B4DJS2|B4DJS2_HUMAN" 2 1453.7413 1.19 67160 15611 2 1453.744422 727.8779 Peroxisomal trans-2-enoyl-CoA reductase OS=Homo sapiens OX=9606 GN=PECR PE=1 SV=2 4.37 2769.5 - 335735 - - - 2.1661 - 2.336 0.445 - 378.3 1 2 0 0.0031 14 0 0 0 3.43E+06 2.88E+06 - - - 4.4559 1 221125_WJC_METTL3_EV_vs_WT_F05.15615.15615.3 6.69E-17 25/96 K.LVQDVANNTNEEAGDGTTTATVLAR.S "sp|P10809|CH60_HUMAN,tr|C9JL25|C9JL25_HUMAN,tr|A0A7I2V2X6|A0A7I2V2X6_HUMAN,tr|A0A7I2YQK6|A0A7I2YQK6_HUMAN,tr|A0A7I2V599|A0A7I2V599_HUMAN,tr|E7EXB4|E7EXB4_HUMAN,tr|A0A7I2YQ71|A0A7I2YQ71_HUMAN,tr|E7ESH4|E7ESH4_HUMAN,tr|A0A7I2V5M1|A0A7I2V5M1_HUMAN,tr|A0A7I2V5K3|A0A7I2V5K3_HUMAN,tr|A0A7I2V369|A0A7I2V369_HUMAN" 11 2559.2413 1.37 67162 15615 3 2559.234068 854.0877 "60 kDa heat shock protein, mitochondrial OS=Homo sapiens OX=9606 GN=HSPD1 PE=1 SV=2" 3.92 2770 - 1.59E+07 - - - -2.8075 - 4.48 0.687 - 853.2 1 2 0 -0.0072 25 0 0 0 1.16E+09 8.44E+08 - - - 9.6475 1 221125_WJC_METTL3_EV_vs_WT_F05.15617.15617.2 3.27E-11 20/32 K.SQVFSTAADGQTQVEIK[136.11].V "sp|P38646|GRP75_HUMAN,tr|A0A7I2V2S7|A0A7I2V2S7_HUMAN,tr|A0A7I2V2G2|A0A7I2V2G2_HUMAN,tr|A0A7I2YQB2|A0A7I2YQB2_HUMAN,tr|D6RCD7|D6RCD7_HUMAN" 5 1815.9094 0.44 67164 15617 2 1815.907524 908.962 "Stress-70 protein, mitochondrial OS=Homo sapiens OX=9606 GN=HSPA9 PE=1 SV=2" 4.37 2770.2 - 1.45E+06 - - - -1.0375 - 3.97 0.623 - 864.6 1 2 0 -0.0019 17 0 0 0 2.17E+08 4.93E+08 - - - 7.0316 0.9998 221125_WJC_METTL3_EV_vs_WT_F05.15622.15622.3 0.000902 Jul-44 K.RETDFYLQSVER.G sp|Q9ULW3|ABT1_HUMAN 1 1541.7474 1.05 67169 15622 3 1541.749224 514.9231 Activator of basal transcription 1 OS=Homo sapiens OX=9606 GN=ABT1 PE=1 SV=1 4.68 2770.9 - 286002 - - - 1.1695 - 1.829 0.406 - 64 1 2 0 0.0018 12 0 0 0 2.03E+06 1.94E+06 - - - 4.7396 0.9997 221125_WJC_METTL3_EV_vs_WT_F05.15626.15626.3 3.25E-05 15/60 K.SELVANNVTLPAGEQR.K "sp|P42166|LAP2A_HUMAN,sp|P42167|LAP2B_HUMAN,tr|G5E972|G5E972_HUMAN" 3 1696.8744 1.27 67172 15626 3 1696.881885 566.6321 "Lamina-associated polypeptide 2, isoform alpha OS=Homo sapiens OX=9606 GN=TMPO PE=1 SV=2" 4.53 2771.3 - 1.13E+06 - - - 4.4034 - 2.366 0.521 - 292.3 1 2 0 0.0075 16 0 0 0 1.75E+07 1.37E+07 - - - 6.5563 1 221125_WJC_METTL3_EV_vs_WT_F05.15627.15627.3 4.61E-08 14/64 K.SQVFSTAADGQTQVEIK[136.11].V "sp|P38646|GRP75_HUMAN,tr|A0A7I2V2S7|A0A7I2V2S7_HUMAN,tr|A0A7I2V2G2|A0A7I2V2G2_HUMAN,tr|A0A7I2YQB2|A0A7I2YQB2_HUMAN,tr|D6RCD7|D6RCD7_HUMAN" 5 1815.9094 0.42 67173 15627 3 1815.908627 606.3104 "Stress-70 protein, mitochondrial OS=Homo sapiens OX=9606 GN=HSPA9 PE=1 SV=2" 4.37 2771.4 - 3.18E+06 - - - -0.4301 - 3.106 0.647 - 216.3 1 2 0 -0.0008 17 0 0 0 1.31E+08 3.10E+08 - - - 8.6163 1 221125_WJC_METTL3_EV_vs_WT_F05.15628.15628.4 2.63E-09 15/144 K.LVQDVANNTNEEAGDGTTTATVLAR.S "sp|P10809|CH60_HUMAN,tr|C9JL25|C9JL25_HUMAN,tr|A0A7I2V2X6|A0A7I2V2X6_HUMAN,tr|A0A7I2YQK6|A0A7I2YQK6_HUMAN,tr|A0A7I2V599|A0A7I2V599_HUMAN,tr|E7EXB4|E7EXB4_HUMAN,tr|A0A7I2YQ71|A0A7I2YQ71_HUMAN,tr|E7ESH4|E7ESH4_HUMAN,tr|A0A7I2V5M1|A0A7I2V5M1_HUMAN,tr|A0A7I2V5K3|A0A7I2V5K3_HUMAN,tr|A0A7I2V369|A0A7I2V369_HUMAN" 11 2559.2413 1.71 67174 15628 4 2559.243179 640.8176 "60 kDa heat shock protein, mitochondrial OS=Homo sapiens OX=9606 GN=HSPD1 PE=1 SV=2" 3.92 2771.5 - 2.26E+06 - - - 0.7526 - 3.012 0.586 - 139.9 1 2 0 0.0019 25 0 0 0 5.65E+07 3.30E+07 - - - 4.6768 1 221125_WJC_METTL3_EV_vs_WT_F05.15629.15629.4 1.46E-11 18/144 K.LVQDVANNTNEEAGDGTTTATVLAR[166.11].S "sp|P10809|CH60_HUMAN,tr|C9JL25|C9JL25_HUMAN,tr|A0A7I2V2X6|A0A7I2V2X6_HUMAN,tr|A0A7I2YQK6|A0A7I2YQK6_HUMAN,tr|A0A7I2V599|A0A7I2V599_HUMAN,tr|E7EXB4|E7EXB4_HUMAN,tr|A0A7I2YQ71|A0A7I2YQ71_HUMAN,tr|E7ESH4|E7ESH4_HUMAN,tr|A0A7I2V5M1|A0A7I2V5M1_HUMAN,tr|A0A7I2V5K3|A0A7I2V5K3_HUMAN,tr|A0A7I2V369|A0A7I2V369_HUMAN" 11 2569.2495 1.7 67175 15629 4 2569.247963 643.3197 "60 kDa heat shock protein, mitochondrial OS=Homo sapiens OX=9606 GN=HSPD1 PE=1 SV=2" 3.92 2771.6 - 1.81E+06 - - - -0.6072 - 3.165 0.659 - 226.7 1 2 0 -0.0016 25 0 0 0 5.62E+07 3.30E+07 - - - 5.328 1 221125_WJC_METTL3_EV_vs_WT_F05.15630.15630.2 1.81E-14 25/48 K.LVQDVANNTNEEAGDGTTTATVLAR.S "sp|P10809|CH60_HUMAN,tr|C9JL25|C9JL25_HUMAN,tr|A0A7I2V2X6|A0A7I2V2X6_HUMAN,tr|A0A7I2YQK6|A0A7I2YQK6_HUMAN,tr|A0A7I2V599|A0A7I2V599_HUMAN,tr|E7EXB4|E7EXB4_HUMAN,tr|A0A7I2YQ71|A0A7I2YQ71_HUMAN,tr|E7ESH4|E7ESH4_HUMAN,tr|A0A7I2V5M1|A0A7I2V5M1_HUMAN,tr|A0A7I2V5K3|A0A7I2V5K3_HUMAN,tr|A0A7I2V369|A0A7I2V369_HUMAN" 11 2559.2413 1.6 67176 15630 2 2561.245447 1280.6279 "60 kDa heat shock protein, mitochondrial OS=Homo sapiens OX=9606 GN=HSPD1 PE=1 SV=2" 3.92 2771.7 - 1.26E+06 - - - 783.1204 - 4.682 0.739 - 1761.6 1 2 0 2.0042 25 0 0 0 6.77E+07 4.24E+07 - - - 7.6653 1 221125_WJC_METTL3_EV_vs_WT_F05.15631.15631.2 6.47E-14 20/32 K.SQVFSTAADGQTQVEIK.V "sp|P38646|GRP75_HUMAN,tr|A0A7I2V2S7|A0A7I2V2S7_HUMAN,tr|A0A7I2V2G2|A0A7I2V2G2_HUMAN,tr|A0A7I2YQB2|A0A7I2YQB2_HUMAN,tr|D6RCD7|D6RCD7_HUMAN" 5 1807.8952 0.44 67177 15631 2 1807.894276 904.9549 "Stress-70 protein, mitochondrial OS=Homo sapiens OX=9606 GN=HSPA9 PE=1 SV=2" 4.37 2771.8 - 1.15E+06 - - - -0.5155 - 3.896 0.684 - 909.1 1 2 0 -0.0009 17 0 0 0 2.17E+08 4.93E+08 - - - 7.4362 1 221125_WJC_METTL3_EV_vs_WT_F05.15632.15632.3 4.90E-09 15/60 R.TAIHEVMEQQTISIAK.A sp|P33993|MCM7_HUMAN 1 1797.9295 1.16 67178 15632 3 1797.929327 600.3171 DNA replication licensing factor MCM7 OS=Homo sapiens OX=9606 GN=MCM7 PE=1 SV=4 5.37 2771.9 - 1.07E+06 - - - -0.0879 - 3.298 0.585 - 414.3 1 2 0 -0.0002 16 0 0 0 1.80E+07 1.55E+07 - - - 8.124 1 221125_WJC_METTL3_EV_vs_WT_F05.15633.15633.2 0.000861 14/20 R.HGESEFNLLGK.L sp|O60825|F262_HUMAN 1 1229.6041 0.05 67179 15633 2 1229.604727 615.8093 "6-phosphofructo-2-kinase\fructose-2,6-bisphosphatase 2 OS=Homo sapiens OX=9606 GN=PFKFB2 PE=1 SV=2" 5.4 2772 - 1.01E+06 - - - 0.5498 - 2.795 0.557 - 580.3 1 2 0 0.0007 11 0 0 0 4.33E+07 7.96E+08 - - - 5.9353 0.9991 221125_WJC_METTL3_EV_vs_WT_F05.15639.15639.3 1.52E-07 13/64 K.SQVFSTAADGQTQVEIK.V "sp|P38646|GRP75_HUMAN,tr|A0A7I2V2S7|A0A7I2V2S7_HUMAN,tr|A0A7I2V2G2|A0A7I2V2G2_HUMAN,tr|A0A7I2YQB2|A0A7I2YQB2_HUMAN,tr|D6RCD7|D6RCD7_HUMAN" 5 1807.8952 0.42 67183 15639 3 1807.883574 603.639 "Stress-70 protein, mitochondrial OS=Homo sapiens OX=9606 GN=HSPA9 PE=1 SV=2" 4.37 2772.8 - 2.29E+06 - - - -6.4351 - 2.631 0.546 - 179.1 1 2 0 -0.0116 17 0 0 0 1.32E+08 3.13E+08 - - - 7.068 1 221125_WJC_METTL3_EV_vs_WT_F05.15640.15640.2 0.000184 15/28 R.DGSLASNPYSGDLTK.F "sp|Q14157|UBP2L_HUMAN,tr|F8W726|F8W726_HUMAN,tr|H7C2T8|H7C2T8_HUMAN,tr|H0Y5H6|H0Y5H6_HUMAN" 4 1523.7104 2.32 67184 15640 2 1523.708326 762.8625 Ubiquitin-associated protein 2-like OS=Homo sapiens OX=9606 GN=UBAP2L PE=1 SV=2 4.21 2772.9 - 1.09E+06 - - - -1.3395 - 2.903 0.594 - 636.2 1 2 0 -0.002 15 0 0 0 1.58E+08 6.82E+07 - - - 6.0478 1 221125_WJC_METTL3_EV_vs_WT_F05.15641.15641.3 0.0042 15/44 K.MIK[136.11]PFFHSLSEK[136.11].Y sp|P10599|THIO_HUMAN 1 1478.7927 0.59 67185 15641 3 1478.791484 493.9382 Thioredoxin OS=Homo sapiens OX=9606 GN=TXN PE=1 SV=3 8.37 2773 - 894365 - - - -0.7932 - 2.778 0.441 - 200.9 1 2 0 -0.0012 12 0 0 0 2.89E+07 4.87E+07 - - - 6.2885 1 221125_WJC_METTL3_EV_vs_WT_F05.15642.15642.3 1.43E-06 18/64 K.KADIGVAMGIAGSDVSK.Q "sp|P05023|AT1A1_HUMAN,sp|P13637|AT1A3_HUMAN,tr|A0A0A0MT26|A0A0A0MT26_HUMAN,tr|A0A2R8YEY8|A0A2R8YEY8_HUMAN,tr|M0R116|M0R116_HUMAN" 5 1617.8396 1.39 67186 15642 3 1617.838125 540.2871 Sodium\potassium-transporting ATPase subunit alpha-1 OS=Homo sapiens OX=9606 GN=ATP1A1 PE=1 SV=1 5.96 2773.1 - 859556 - - - -0.916 - 3.461 0.555 - 487 1 2 0 -0.0015 17 0 0 0 2.65E+07 1.90E+07 - - - 7.8638 1 221125_WJC_METTL3_EV_vs_WT_F05.15644.15644.3 2.75E-07 17/48 K.C[160.03]C[160.03]SDFDLHSELER[166.11].S sp|Q69YN4|VIR_HUMAN 1 1676.6798 0.64 67188 15644 3 1676.681209 559.9006 Protein virilizer homolog OS=Homo sapiens OX=9606 GN=VIRMA PE=1 SV=2 4.31 2773.4 - 593548 - - - 0.8248 - 2.879 0.684 - 405.6 1 2 0 0.0014 13 0 0 0 3.47E+06 5.44E+06 - - - 9.0326 1 221125_WJC_METTL3_EV_vs_WT_F05.15645.15645.3 2.47E-08 13/40 R.HGESEFNLLGK.L sp|O60825|F262_HUMAN 1 1229.6041 0.05 67189 15645 3 1229.601954 410.8753 "6-phosphofructo-2-kinase\fructose-2,6-bisphosphatase 2 OS=Homo sapiens OX=9606 GN=PFKFB2 PE=1 SV=2" 5.4 2773.5 - 585340 - - - -1.7054 - 2.528 0.587 - 249.6 1 2 0 -0.0021 11 0 0 0 1.21E+07 2.27E+08 - - - 7.7186 0.9987 221125_WJC_METTL3_EV_vs_WT_F05.15646.15646.4 0.000481 15/90 K.EIVVIHQDPEALK[136.11]DIK[136.11].S "sp|P41252|SYIC_HUMAN,tr|A0A804HL54|A0A804HL54_HUMAN,tr|A0A804HIV9|A0A804HIV9_HUMAN,tr|A0A804HJN6|A0A804HJN6_HUMAN,tr|A0A804HHW9|A0A804HHW9_HUMAN,tr|A0A0A0MSX9|A0A0A0MSX9_HUMAN,tr|J3KR24|J3KR24_HUMAN,tr|A0A804HJ36|A0A804HJ36_HUMAN" 8 1862.0484 0.83 67190 15646 4 1862.045563 466.5194 "Isoleucine--tRNA ligase, cytoplasmic OS=Homo sapiens OX=9606 GN=IARS1 PE=1 SV=2" 4.75 2773.7 - 578494 - - - -1.5311 - 2.516 0.349 - 163.1 1 2 1 -0.0029 16 0 0 0 1.01E+07 1.22E+07 - - - 2.5879 0.9963 221125_WJC_METTL3_EV_vs_WT_F05.15648.15648.3 0.0315 Jul-44 K.HGGGTESLFFDK[136.11].V sp|Q96ST3|SIN3A_HUMAN 1 1301.6132 1.12 67192 15648 3 1301.610246 434.8783 Paired amphipathic helix protein Sin3a OS=Homo sapiens OX=9606 GN=SIN3A PE=1 SV=2 5.32 2773.9 - 265763 - - - -2.2434 - 1.695 0.263 - 61.5 1 2 0 -0.0029 12 0 0 0 4.86E+06 4.33E+06 - - - 2.934 1 221125_WJC_METTL3_EV_vs_WT_F05.15653.15653.2 2.50E-15 27/48 K.LVQDVANNTNEEAGDGTTTATVLAR[166.11].S "sp|P10809|CH60_HUMAN,tr|C9JL25|C9JL25_HUMAN,tr|A0A7I2V2X6|A0A7I2V2X6_HUMAN,tr|A0A7I2YQK6|A0A7I2YQK6_HUMAN,tr|A0A7I2V599|A0A7I2V599_HUMAN,tr|E7EXB4|E7EXB4_HUMAN,tr|A0A7I2YQ71|A0A7I2YQ71_HUMAN,tr|E7ESH4|E7ESH4_HUMAN,tr|A0A7I2V5M1|A0A7I2V5M1_HUMAN,tr|A0A7I2V5K3|A0A7I2V5K3_HUMAN,tr|A0A7I2V369|A0A7I2V369_HUMAN" 11 2569.2495 1.6 67196 15653 2 2569.246989 1285.632 "60 kDa heat shock protein, mitochondrial OS=Homo sapiens OX=9606 GN=HSPD1 PE=1 SV=2" 3.92 2774.4 - 3.26E+06 - - - -0.9863 - 5.061 0.731 - 2255.5 1 2 0 -0.0025 25 0 0 0 6.77E+07 4.24E+07 - - - 8.4261 1 221125_WJC_METTL3_EV_vs_WT_F05.15656.15656.3 9.47E-07 17/52 R.DLHGQAESAAAVWK.G "sp|Q5TA31|RN187_HUMAN,tr|A0A1X7SBW3|A0A1X7SBW3_HUMAN" 2 1481.7263 4.55 67199 15656 3 1481.726713 494.916 E3 ubiquitin-protein ligase RNF187 OS=Homo sapiens OX=9606 GN=RNF187 PE=1 SV=2 5.32 2774.8 - 746046 - - - 0.2841 - 2.836 0.499 - 533.7 1 2 0 0.0004 14 0 0 0 1.46E+07 3.21E+06 - - - 6.8734 0.9997 221125_WJC_METTL3_EV_vs_WT_F05.15657.15657.4 6.20E-05 15/90 K.EIVVIHQDPEALKDIK.S "sp|P41252|SYIC_HUMAN,tr|A0A804HL54|A0A804HL54_HUMAN,tr|A0A804HIV9|A0A804HIV9_HUMAN,tr|A0A804HJN6|A0A804HJN6_HUMAN,tr|A0A804HHW9|A0A804HHW9_HUMAN,tr|A0A0A0MSX9|A0A0A0MSX9_HUMAN,tr|J3KR24|J3KR24_HUMAN,tr|A0A804HJ36|A0A804HJ36_HUMAN" 8 1846.02 0.83 67200 15657 4 1846.019795 462.5123 "Isoleucine--tRNA ligase, cytoplasmic OS=Homo sapiens OX=9606 GN=IARS1 PE=1 SV=2" 4.75 2774.9 - 720111 - - - -0.1186 - 2.651 0.444 - 146.8 1 2 1 -0.0002 16 0 0 0 1.01E+07 1.22E+07 - - - 3.4339 0.9997 221125_WJC_METTL3_EV_vs_WT_F05.15659.15659.2 9.64E-05 Sep-36 K.EGPEPPEEVPPPTTPPVPK.V sp|P48634|PRC2A_HUMAN 1 1993.0044 2.15 67202 15659 2 1993.00615 997.5095 Protein PRRC2A OS=Homo sapiens OX=9606 GN=PRRC2A PE=1 SV=3 4.09 2775.1 - 426170 - - - 0.866 - 1.731 0.462 - 110.4 1 2 0 0.0017 19 0 0 0 7.57E+06 3.53E+06 - - - 3.8018 1 221125_WJC_METTL3_EV_vs_WT_F05.15661.15661.2 3.51E-05 14/28 R.DGSLASNPYSGDLTK[136.11].F "sp|Q14157|UBP2L_HUMAN,tr|F8W726|F8W726_HUMAN,tr|H7C2T8|H7C2T8_HUMAN,tr|H0Y5H6|H0Y5H6_HUMAN" 4 1531.7246 2.32 67203 15661 2 1531.720521 766.8696 Ubiquitin-associated protein 2-like OS=Homo sapiens OX=9606 GN=UBAP2L PE=1 SV=2 4.21 2775.4 - 1.71E+06 - - - -2.6415 - 2.768 0.577 - 587.3 1 2 0 -0.004 15 0 0 0 1.58E+08 6.82E+07 - - - 5.8046 1 221125_WJC_METTL3_EV_vs_WT_F05.15665.15665.3 8.46E-14 23/96 K.LVQDVANNTNEEAGDGTTTATVLAR[166.11].S "sp|P10809|CH60_HUMAN,tr|C9JL25|C9JL25_HUMAN,tr|A0A7I2V2X6|A0A7I2V2X6_HUMAN,tr|A0A7I2YQK6|A0A7I2YQK6_HUMAN,tr|A0A7I2V599|A0A7I2V599_HUMAN,tr|E7EXB4|E7EXB4_HUMAN,tr|A0A7I2YQ71|A0A7I2YQ71_HUMAN,tr|E7ESH4|E7ESH4_HUMAN,tr|A0A7I2V5M1|A0A7I2V5M1_HUMAN,tr|A0A7I2V5K3|A0A7I2V5K3_HUMAN,tr|A0A7I2V369|A0A7I2V369_HUMAN" 11 2569.2495 1.37 67206 15665 3 2569.246602 857.4238 "60 kDa heat shock protein, mitochondrial OS=Homo sapiens OX=9606 GN=HSPD1 PE=1 SV=2" 3.92 2775.7 - 6.91E+07 - - - -1.1369 - 4.191 0.685 - 767.8 1 2 0 -0.0029 25 0 0 0 1.16E+09 8.44E+08 - - - 9.4729 1 221125_WJC_METTL3_EV_vs_WT_F05.15667.15667.3 2.63E-07 17/64 K.K[136.11]ADIGVAMGIAGSDVSK[136.11].Q "sp|P05023|AT1A1_HUMAN,sp|P13637|AT1A3_HUMAN,tr|A0A0A0MT26|A0A0A0MT26_HUMAN,tr|A0A2R8YEY8|A0A2R8YEY8_HUMAN,tr|M0R116|M0R116_HUMAN" 5 1633.868 1.39 67208 15667 3 1633.867472 545.6299 Sodium\potassium-transporting ATPase subunit alpha-1 OS=Homo sapiens OX=9606 GN=ATP1A1 PE=1 SV=1 5.96 2775.9 - 1.42E+06 - - - -0.3274 - 3.187 0.535 - 483.5 1 2 0 -0.0005 17 0 0 0 2.65E+07 1.90E+07 - - - 7.4328 1 221125_WJC_METTL3_EV_vs_WT_F05.15668.15668.2 1.31E-09 21/34 K.SAVATAEALGLDRPASDK.Q "sp|Q6W2J9|BCOR_HUMAN,tr|H7BZ37|H7BZ37_HUMAN,tr|H7C2V9|H7C2V9_HUMAN,tr|A0A5F9ZGX7|A0A5F9ZGX7_HUMAN,tr|H7BYY2|H7BYY2_HUMAN,tr|H7C231|H7C231_HUMAN" 6 1770.9112 2.4 67209 15668 2 1770.912841 886.4629 BCL-6 corepressor OS=Homo sapiens OX=9606 GN=BCOR PE=1 SV=1 4.56 2776 - 842461 - - - 0.9312 - 4.168 0.617 - 1592.7 1 2 0 0.0016 18 0 0 0 1.85E+07 7.69E+06 - - - 7.1071 0.9986 221125_WJC_METTL3_EV_vs_WT_F05.15669.15669.3 0.00224 14/52 R.DLHGQAESAAAVWK[136.11].G "sp|Q5TA31|RN187_HUMAN,tr|A0A1X7SBW3|A0A1X7SBW3_HUMAN" 2 1489.7405 4.56 67210 15669 3 1489.73641 497.5874 E3 ubiquitin-protein ligase RNF187 OS=Homo sapiens OX=9606 GN=RNF187 PE=1 SV=2 5.32 2776.1 - 426404 - - - -2.7401 - 2.002 0.317 - 160.4 1 2 0 -0.0041 14 0 0 0 1.47E+07 3.21E+06 - - - 3.9178 0.9998 221125_WJC_METTL3_EV_vs_WT_F05.15676.15676.2 0.00493 20-Nov K.EEEWDPEYTPK.S "sp|Q9NYF8|BCLF1_HUMAN,sp|Q9Y2W1|TR150_HUMAN,tr|A0A3B3ITZ9|A0A3B3ITZ9_HUMAN,tr|H0YF14|H0YF14_HUMAN" 4 1421.5987 2.85 67215 15676 2 1421.600521 711.8066 Bcl-2-associated transcription factor 1 OS=Homo sapiens OX=9606 GN=BCLAF1 PE=1 SV=2 3.91 2776.9 - 880407 - - - 1.2873 - 2.201 0.519 - 433.5 1 2 0 0.0018 11 0 0 0 3.66E+07 1.28E+07 - - - 5.008 0.9998 221125_WJC_METTL3_EV_vs_WT_F05.15677.15677.3 2.26E-06 17/72 K.EGPEPPEEVPPPTTPPVPK.V sp|P48634|PRC2A_HUMAN 1 1993.0044 1.81 67216 15677 3 1992.997661 665.3421 Protein PRRC2A OS=Homo sapiens OX=9606 GN=PRRC2A PE=1 SV=3 4.09 2777.1 - 717470 - - - -3.3934 - 2.572 0.478 - 162.7 1 2 0 -0.0068 19 0 0 0 8.74E+06 4.82E+06 - - - 6.1883 0.9999 221125_WJC_METTL3_EV_vs_WT_F05.15679.15679.2 1.14E-06 24-Oct R.SSNPSISDDSYFR.K "sp|Q8IX01|SUGP2_HUMAN,tr|M0R216|M0R216_HUMAN,tr|M0R065|M0R065_HUMAN,tr|M0R2Z9|M0R2Z9_HUMAN,tr|M0R3F6|M0R3F6_HUMAN" 5 1473.6372 1.16 67218 15679 2 1473.637929 737.8259 SURP and G-patch domain-containing protein 2 OS=Homo sapiens OX=9606 GN=SUGP2 PE=1 SV=2 4.21 2777.3 - 328272 - - - 0.4933 - 2.26 0.519 - 324.2 1 2 0 0.0007 13 0 0 0 1.33E+07 1.15E+07 - - - 4.9668 0.9905 221125_WJC_METTL3_EV_vs_WT_F05.15686.15686.2 0.0473 14-Jul R.LPLQDVYK.L "sp|Q05639|EF1A2_HUMAN,sp|P68104|EF1A1_HUMAN,sp|Q5VTE0|EF1A3_HUMAN,tr|A0A7I2V659|A0A7I2V659_HUMAN,tr|A0A7I2V3H3|A0A7I2V3H3_HUMAN,tr|A0A2U3TZH3|A0A2U3TZH3_HUMAN,tr|A0A7I2V5N4|A0A7I2V5N4_HUMAN,tr|A0A087WVQ9|A0A087WVQ9_HUMAN,tr|A0A087WV01|A0A087WV01_HUMAN" 9 974.5437 21.65 67223 15686 2 974.542079 488.2791 Elongation factor 1-alpha 2 OS=Homo sapiens OX=9606 GN=EEF1A2 PE=1 SV=1 5.83 2778.2 - 343443 - - - -1.6459 - 1.415 0.126 - 129.9 1 2 0 -0.0016 8 0 0 0 1.42E+07 6.58E+05 - - - 1.0181 1 221125_WJC_METTL3_EV_vs_WT_F05.15692.15692.2 1.24E-12 17/32 R.YSLQSANASSLSSGQLK[136.11].S "sp|Q9H2P0|ADNP_HUMAN,tr|A0A2R8Y6X0|A0A2R8Y6X0_HUMAN,tr|A0A669KBJ7|A0A669KBJ7_HUMAN" 3 1747.8832 0.98 67227 15692 2 1747.882518 874.9489 Activity-dependent neuroprotector homeobox protein OS=Homo sapiens OX=9606 GN=ADNP PE=1 SV=1 8.59 2778.9 - 1.57E+06 - - - -0.3862 - 3.324 0.659 - 1109.4 1 2 0 -0.0007 17 0 0 0 2.42E+07 2.46E+07 - - - 6.8613 1 221125_WJC_METTL3_EV_vs_WT_F05.15695.15695.2 6.00E-08 17/34 K.SAVATAEALGLDR[166.11]PASDK[136.11].Q "sp|Q6W2J9|BCOR_HUMAN,tr|H7BZ37|H7BZ37_HUMAN,tr|H7C2V9|H7C2V9_HUMAN,tr|A0A5F9ZGX7|A0A5F9ZGX7_HUMAN,tr|H7BYY2|H7BYY2_HUMAN,tr|H7C231|H7C231_HUMAN" 6 1788.9337 2.4 67230 15695 2 1788.940572 895.4741 BCL-6 corepressor OS=Homo sapiens OX=9606 GN=BCOR PE=1 SV=1 4.56 2779.2 - 556991 - - - 3.8626 - 3.751 0.649 - 852.5 1 2 0 0.0069 18 0 0 0 1.85E+07 7.69E+06 - - - 7.0826 0.9997 221125_WJC_METTL3_EV_vs_WT_F05.15696.15696.3 0.000436 Oct-52 K.LAQANGWGVMVSHR[166.11].S "sp|P06733|ENOA_HUMAN,tr|A0A2R8Y6G6|A0A2R8Y6G6_HUMAN" 2 1534.7702 0.86 67231 15696 3 1534.770717 512.5974 Alpha-enolase OS=Homo sapiens OX=9606 GN=ENO1 PE=1 SV=2 9.76 2779.3 - 375699 - - - 0.3134 - 1.929 0.354 - 153 1 2 0 0.0005 14 0 0 0 4.42E+06 5.13E+06 - - - 4.2326 1 221125_WJC_METTL3_EV_vs_WT_F05.15700.15700.2 1.56E-10 21/32 R.YSLQSANASSLSSGQLK.S "sp|Q9H2P0|ADNP_HUMAN,tr|A0A2R8Y6X0|A0A2R8Y6X0_HUMAN,tr|A0A669KBJ7|A0A669KBJ7_HUMAN" 3 1739.869 0.98 67233 15700 2 1739.869559 870.9418 Activity-dependent neuroprotector homeobox protein OS=Homo sapiens OX=9606 GN=ADNP PE=1 SV=1 8.59 2779.8 - 1.29E+06 - - - 0.3253 - 3.713 0.602 - 1531.5 1 2 0 0.0006 17 0 0 0 2.42E+07 2.46E+07 - - - 6.7124 1 221125_WJC_METTL3_EV_vs_WT_F05.15702.15702.3 7.98E-07 21/56 R.DDTIYEDEDVK[136.11]EAIR[166.11].R "sp|P14927|QCR7_HUMAN,tr|E5RHG9|E5RHG9_HUMAN,tr|B7Z2R2|B7Z2R2_HUMAN" 3 1827.8493 1.81 67235 15702 3 1827.846557 610.2904 Cytochrome b-c1 complex subunit 7 OS=Homo sapiens OX=9606 GN=UQCRB PE=1 SV=2 3.9 2780 - 3.24E+06 - - - -1.5133 - 3.614 0.645 - 978.5 1 2 1 -0.0028 15 0 0 0 8.40E+07 4.64E+07 - - - 9.0829 0.9999 221125_WJC_METTL3_EV_vs_WT_F05.15703.15703.2 1.91E-05 20-Dec K.EEEWDPEYTPK[136.11].S "sp|Q9NYF8|BCLF1_HUMAN,sp|Q9Y2W1|TR150_HUMAN,tr|A0A3B3ITZ9|A0A3B3ITZ9_HUMAN,tr|H0YF14|H0YF14_HUMAN" 4 1429.6129 2.85 67236 15703 2 1429.612761 715.8137 Bcl-2-associated transcription factor 1 OS=Homo sapiens OX=9606 GN=BCLAF1 PE=1 SV=2 3.91 2780.1 - 793820 - - - -0.0909 - 2.395 0.574 - 578.9 1 2 0 -0.0001 11 0 0 0 3.66E+07 1.28E+07 - - - 5.6432 0.9963 221125_WJC_METTL3_EV_vs_WT_F05.15704.15704.3 0.00982 Aug-32 K.DYAFVHMER.A "sp|Q9BWF3|RBM4_HUMAN,sp|Q9BQ04|RBM4B_HUMAN,tr|E9PM61|E9PM61_HUMAN,tr|D6R9K7|D6R9K7_HUMAN,tr|J3QRR5|J3QRR5_HUMAN,tr|E9PB51|E9PB51_HUMAN,tr|U3KQD5|U3KQD5_HUMAN,tr|E9PLB0|E9PLB0_HUMAN" 8 1166.5179 1.4 67237 15704 3 1166.515887 389.8466 RNA-binding protein 4 OS=Homo sapiens OX=9606 GN=RBM4 PE=1 SV=1 5.32 2780.3 - 690205 - - - -1.7076 - 1.301 0.3 - 94.6 1 2 0 -0.002 9 0 0 0 5.49E+06 3.93E+06 - - - 2.6772 1 221125_WJC_METTL3_EV_vs_WT_F05.15705.15705.2 7.85E-08 24-Oct R.SSNPSISDDSYFR[166.11].K "sp|Q8IX01|SUGP2_HUMAN,tr|M0R216|M0R216_HUMAN,tr|M0R065|M0R065_HUMAN,tr|M0R2Z9|M0R2Z9_HUMAN,tr|M0R3F6|M0R3F6_HUMAN" 5 1483.6455 1.16 67238 15705 2 1483.638935 742.83 SURP and G-patch domain-containing protein 2 OS=Homo sapiens OX=9606 GN=SUGP2 PE=1 SV=2 4.21 2780.4 - 566083 - - - -4.406 - 2.198 0.65 - 322.3 1 2 0 -0.0065 13 0 0 0 1.33E+07 1.15E+07 - - - 5.8611 0.8972 221125_WJC_METTL3_EV_vs_WT_F05.15706.15706.3 0.733 15/68 K.LAEIGAPIQGNR[166.11]EELVER[166.11].L "sp|Q13435|SF3B2_HUMAN,tr|E9PPJ0|E9PPJ0_HUMAN,tr|H0YCG1|H0YCG1_HUMAN,tr|E9PJ04|E9PJ04_HUMAN,tr|E9PJT3|E9PJT3_HUMAN" 5 2013.0758 0.35 67239 15706 3 2013.078509 672.0325 Splicing factor 3B subunit 2 OS=Homo sapiens OX=9606 GN=SF3B2 PE=1 SV=2 4.49 2780.5 - 458275 - - - 1.3492 - 1.94 0.112 - 278.4 1 2 1 0.0027 18 0 0 0 1.76E+06 4.98E+06 - - - 1.4381 0.9998 221125_WJC_METTL3_EV_vs_WT_F05.15711.15711.3 6.53E-06 16/52 R.ELISNSSDALDK[136.11]IR[166.11].Y "sp|P07900|HS90A_HUMAN,tr|G3V2J8|G3V2J8_HUMAN" 2 1577.838 0.57 67242 15711 3 1577.834525 526.9533 Heat shock protein HSP 90-alpha OS=Homo sapiens OX=9606 GN=HSP90AA1 PE=1 SV=5 4.56 2781.1 - 1.64E+06 - - - -2.184 - 2.953 0.511 - 359.4 1 2 1 -0.0034 14 0 0 0 7.38E+06 1.31E+07 - - - 7.1138 1 221125_WJC_METTL3_EV_vs_WT_F05.15712.15712.3 3.73E-05 16/68 K.LPGGELNPGEDEVEGLKR.L "sp|O43809|CPSF5_HUMAN,tr|H3BV41|H3BV41_HUMAN,tr|H3BND3|H3BND3_HUMAN" 3 1907.9589 1.05 67243 15712 3 1907.958871 636.9936 Cleavage and polyadenylation specificity factor subunit 5 OS=Homo sapiens OX=9606 GN=NUDT21 PE=1 SV=1 4.25 2781.2 - 1.21E+06 - - - 0 - 3.326 0.549 - 307.1 1 2 0 0 18 0 0 0 1.90E+07 1.82E+07 - - - 7.6533 1 221125_WJC_METTL3_EV_vs_WT_F05.15713.15713.3 5.60E-05 19/68 K.SAVATAEALGLDR[166.11]PASDK[136.11].Q "sp|Q6W2J9|BCOR_HUMAN,tr|H7BZ37|H7BZ37_HUMAN,tr|H7C2V9|H7C2V9_HUMAN,tr|A0A5F9ZGX7|A0A5F9ZGX7_HUMAN,tr|H7BYY2|H7BYY2_HUMAN,tr|H7C231|H7C231_HUMAN" 6 1788.9337 1.71 67244 15713 3 1788.931884 597.3185 BCL-6 corepressor OS=Homo sapiens OX=9606 GN=BCOR PE=1 SV=1 4.56 2781.2 - 4.19E+06 - - - -0.9939 - 4.15 0.564 - 557.7 1 2 0 -0.0018 18 0 0 0 2.22E+08 1.30E+08 - - - 8.3712 0.9992 221125_WJC_METTL3_EV_vs_WT_F05.15717.15717.3 2.16E-05 Dec-44 R.DAGLSFK[136.11]DDMPK[136.11].S "sp|Q9NW64|RBM22_HUMAN,tr|E5RJW4|E5RJW4_HUMAN,tr|E5RHA8|E5RHA8_HUMAN" 3 1338.6461 0.53 67248 15717 3 1338.641132 447.2226 Pre-mRNA-splicing factor RBM22 OS=Homo sapiens OX=9606 GN=RBM22 PE=1 SV=1 4.43 2781.7 - 631098 - - - -3.6754 - 2.163 0.526 - 180.8 1 2 1 -0.0049 12 0 0 0 3.66E+06 6.89E+06 - - - 6.5415 0.9998 221125_WJC_METTL3_EV_vs_WT_F05.15718.15718.4 2.90E-05 14/96 K.IFVGGLPYHTTDASLRK.Y "sp|Q9H0Z9|RBM38_HUMAN,sp|Q9BX46|RBM24_HUMAN,tr|F6VZ39|F6VZ39_HUMAN,tr|E9PSF1|E9PSF1_HUMAN" 4 1874.005 2.82 67249 15718 4 1874.002221 469.5085 RNA-binding protein 38 OS=Homo sapiens OX=9606 GN=RBM38 PE=1 SV=2 8.6 2781.9 - 513394 - - - -1.5005 - 2.809 0.373 - 147.6 1 2 0 -0.0028 17 0 0 0 4.27E+06 1.51E+06 - - - 2.8304 1 221125_WJC_METTL3_EV_vs_WT_F05.15721.15721.3 1.87E-08 15/56 R.DDTIYEDEDVKEAIR.R "sp|P14927|QCR7_HUMAN,tr|E5RHG9|E5RHG9_HUMAN,tr|B7Z2R2|B7Z2R2_HUMAN" 3 1809.8269 1.86 67250 15721 3 1809.826009 604.2829 Cytochrome b-c1 complex subunit 7 OS=Homo sapiens OX=9606 GN=UQCRB PE=1 SV=2 3.9 2782.3 - 6.79E+06 - - - -0.4663 - 3.328 0.605 - 415.3 1 2 1 -0.0008 15 0 0 0 8.37E+07 4.51E+07 - - - 8.4223 0.9999 221125_WJC_METTL3_EV_vs_WT_F05.15726.15726.3 2.80E-05 13/44 R.LQHTLQQVLDQR[166.11].E sp|O00273|DFFA_HUMAN 1 1487.8084 0.71 67255 15726 3 1487.807824 496.9434 DNA fragmentation factor subunit alpha OS=Homo sapiens OX=9606 GN=DFFA PE=1 SV=1 6.74 2782.9 - 598606 - - - -0.3838 - 2.627 0.347 - 222.1 1 2 0 -0.0006 12 0 0 0 1.14E+07 1.61E+07 - - - 5.0857 1 221125_WJC_METTL3_EV_vs_WT_F05.15727.15727.2 3.65E-06 14/30 K.QGFNVVVESGAGEASK.F "sp|Q13423|NNTM_HUMAN,tr|D6RHU2|D6RHU2_HUMAN,tr|A0A590UJA4|A0A590UJA4_HUMAN,tr|D6RAI5|D6RAI5_HUMAN,tr|A0A590UK15|A0A590UK15_HUMAN,tr|A0A590UJM2|A0A590UJM2_HUMAN,tr|A0A590UK29|A0A590UK29_HUMAN,tr|A0A590UKC7|A0A590UKC7_HUMAN" 8 1577.7686 1.42 67256 15727 2 1577.762995 789.8916 "NAD(P) transhydrogenase, mitochondrial OS=Homo sapiens OX=9606 GN=NNT PE=1 SV=3" 4.53 2783 - 496857 - - - -3.5208 - 2.9 0.576 - 645.1 1 2 0 -0.0056 16 0 0 0 5.38E+06 3.78E+06 - - - 5.9112 0.9999 221125_WJC_METTL3_EV_vs_WT_F05.15731.15731.3 0.00098 13/44 R.LQHTLQQVLDQR.E sp|O00273|DFFA_HUMAN 1 1477.8001 0.68 67260 15731 3 1477.801446 493.6073 DNA fragmentation factor subunit alpha OS=Homo sapiens OX=9606 GN=DFFA PE=1 SV=1 6.74 2783.5 - 425098 - - - 0.8939 - 2.674 0.372 - 232.5 1 2 0 0.0013 12 0 0 0 1.07E+07 1.57E+07 - - - 5.4134 0.9967 221125_WJC_METTL3_EV_vs_WT_F05.15732.15732.3 0.000386 Dec-44 K.NKVEDSGIFTIK.N sp|Q16706|MA2A1_HUMAN 1 1349.7191 2.21 67261 15732 3 1349.718573 450.9136 Alpha-mannosidase 2 OS=Homo sapiens OX=9606 GN=MAN2A1 PE=1 SV=2 6.07 2783.6 - 318433 - - - -0.3764 - 2.424 0.23 - 233.3 1 2 1 -0.0005 12 0 0 0 7.86E+06 3.56E+06 - - - 3.5584 1 221125_WJC_METTL3_EV_vs_WT_F05.15736.15736.3 3.42E-10 17/68 K.MILIQDGSQNTNVDK[136.11]PLR[166.11].L "sp|Q92945|FUBP2_HUMAN,tr|M0R0I5|M0R0I5_HUMAN,tr|M0QYH3|M0QYH3_HUMAN,tr|M0R0C6|M0R0C6_HUMAN,tr|A0A087WTP3|A0A087WTP3_HUMAN" 5 2059.0851 1.13 67263 15736 3 2059.087003 687.369 Far upstream element-binding protein 2 OS=Homo sapiens OX=9606 GN=KHSRP PE=1 SV=4 5.71 2784.2 - 2.77E+06 - - - 0.9271 - 3.234 0.604 - 285.1 1 2 0 0.0019 18 0 0 0 9.34E+07 8.26E+07 - - - 8.1962 1 221125_WJC_METTL3_EV_vs_WT_F05.15738.15738.3 8.24E-11 22/68 K.MILIQDGSQNTNVDKPLR.L "sp|Q92945|FUBP2_HUMAN,tr|M0R0I5|M0R0I5_HUMAN,tr|M0QYH3|M0QYH3_HUMAN,tr|M0R0C6|M0R0C6_HUMAN,tr|A0A087WTP3|A0A087WTP3_HUMAN" 5 2041.0626 1.12 67265 15738 3 2041.065543 681.3615 Far upstream element-binding protein 2 OS=Homo sapiens OX=9606 GN=KHSRP PE=1 SV=4 5.71 2784.3 - 2.42E+06 - - - 1.4301 - 4.056 0.669 - 516.2 1 2 0 0.0029 18 0 0 0 9.26E+07 8.26E+07 - - - 9.4845 0.9221 221125_WJC_METTL3_EV_vs_WT_F05.15743.15743.3 0.000597 Oct-60 Y.SALILHDDEVTVTEDK[136.11].L sp|P05386|RLA1_HUMAN 1 1791.8982 2.12 67270 15743 3 1791.893628 598.3067 60S acidic ribosomal protein P1 OS=Homo sapiens OX=9606 GN=RPLP1 PE=1 SV=1 4.1 2784.9 - 825590 - - - -2.537 - 2.166 0.332 - 126.9 1 1 0 -0.0045 16 0 0 0 1.12E+07 5.31E+06 - - - 4.2233 1 221125_WJC_METTL3_EV_vs_WT_F05.15746.15746.2 1.16E-06 14/24 R.DELADEIANSSGK.G sp|P35579|MYH9_HUMAN 1 1347.6154 1.72 67273 15746 2 1347.610539 674.815 Myosin-9 OS=Homo sapiens OX=9606 GN=MYH9 PE=1 SV=4 3.92 2785.3 - 401163 - - - -3.6101 - 2.443 0.618 - 417.6 1 2 0 -0.0049 13 0 0 0 3.92E+06 2.28E+06 - - - 5.8965 1 221125_WJC_METTL3_EV_vs_WT_F05.15748.15748.2 8.18E-14 15/36 K.AANAAENDFSVSQAEMSSR.Q "sp|Q8NE71|ABCF1_HUMAN,tr|Q5STZ8|Q5STZ8_HUMAN,tr|A0A0G2JJB9|A0A0G2JJB9_HUMAN,tr|H0YGW7|H0YGW7_HUMAN" 4 1983.8592 0.97 67275 15748 2 1983.859376 992.9369 ATP-binding cassette sub-family F member 1 OS=Homo sapiens OX=9606 GN=ABCF1 PE=1 SV=2 4.14 2785.6 - 237027 - - - 0.0721 - 3.616 0.797 - 655.1 1 2 0 0.0001 19 0 0 0 3.02E+06 3.11E+06 - - - 8.0877 0.9845 221125_WJC_METTL3_EV_vs_WT_F05.15756.15756.3 1.40E-06 14/48 R.SK[136.11]VDEAVAVLQAH.H "sp|Q13310|PABP4_HUMAN,sp|Q9H361|PABP3_HUMAN,sp|P11940|PABP1_HUMAN,tr|A0A7I2V5W9|A0A7I2V5W9_HUMAN,tr|H0YAS6|H0YAS6_HUMAN,tr|H0YEU6|H0YEU6_HUMAN,tr|H0YB75|H0YB75_HUMAN,tr|H0YAS7|H0YAS7_HUMAN,tr|A0A7I2YQE4|A0A7I2YQE4_HUMAN,tr|A0A7I2V649|A0A7I2V649_HUMAN,tr|B1ANR0|B1ANR0_HUMAN,tr|H0YC10|H0YC10_HUMAN,tr|A0A7I2V4L7|A0A7I2V4L7_HUMAN,tr|H0YER0|H0YER0_HUMAN,tr|H0YAR2|H0YAR2_HUMAN,tr|E7ERJ7|E7ERJ7_HUMAN,tr|A0A7I2V598|A0A7I2V598_HUMAN,tr|A0A7I2YQ88|A0A7I2YQ88_HUMAN,tr|A0A7I2V4V6|A0A7I2V4V6_HUMAN,tr|H0Y5F5|H0Y5F5_HUMAN,tr|A0A087WTT1|A0A087WTT1_HUMAN,tr|H0Y6X6|H0Y6X6_HUMAN,tr|A0A7I2YQ90|A0A7I2YQ90_HUMAN,tr|A0A7I2V4N4|A0A7I2V4N4_HUMAN,tr|E7EQV3|E7EQV3_HUMAN" 25 1373.7394 1.1 67281 15756 3 1373.739602 458.9204 Polyadenylate-binding protein 4 OS=Homo sapiens OX=9606 GN=PABPC4 PE=1 SV=1 5.3 2786.4 - 759099 - - - 0.1259 - 2.719 0.462 - 306 1 1 1 0.0002 13 0 0 0 2.91E+07 2.66E+07 - - - 6.4028 1 221125_WJC_METTL3_EV_vs_WT_F05.15757.15757.3 1.36E-09 24/68 N.LLC[160.03]GEEQGSDAALHFNPR.L sp|P47929|LEG7_HUMAN 1 2012.9374 999 67282 15757 3 2012.936044 671.9864 Galectin-7 OS=Homo sapiens OX=9606 GN=LGALS7 PE=1 SV=2 4.65 2786.6 - 628587 - - - -0.6856 - 3.835 0.651 - 747.1 1 1 0 -0.0014 18 0 0 0 1.80E+07 0.00E+00 - - - 9.1447 0.9999 221125_WJC_METTL3_EV_vs_WT_F05.15758.15758.3 0.00056 Nov-36 K.K[136.11]QELLEALTK[136.11].H "sp|P12956|XRCC6_HUMAN,tr|B1AHC9|B1AHC9_HUMAN" 2 1187.7096 1.12 67283 15758 3 1187.709795 396.9105 X-ray repair cross-complementing protein 6 OS=Homo sapiens OX=9606 GN=XRCC6 PE=1 SV=2 6.14 2786.7 - 432529 - - - 0.1313 - 2.362 0.415 - 187.3 1 2 0 0.0002 10 0 0 0 1.86E+07 1.66E+07 - - - 5.6769 0.9867 221125_WJC_METTL3_EV_vs_WT_F05.15769.15769.3 0.00111 Dec-64 L.LQDDAHPTLVTYADHSK[136.11].L "sp|Q86U44|MTA70_HUMAN,tr|F5H6D8|F5H6D8_HUMAN,tr|H0YFV6|H0YFV6_HUMAN,tr|B4DTN4|B4DTN4_HUMAN" 4 1917.9312 0.02 67292 15769 3 1917.933447 640.3177 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 5.13 2788 - 1.44E+06 - - - 1.1684 - 2.285 0.404 - 143.1 1 1 0 0.0022 17 0 0 0 4.43E+05 1.84E+07 - - - 5.1312 1 221125_WJC_METTL3_EV_vs_WT_F05.15770.15770.3 2.48E-08 15/72 K.AANAAENDFSVSQAEMSSR.Q "sp|Q8NE71|ABCF1_HUMAN,tr|Q5STZ8|Q5STZ8_HUMAN,tr|A0A0G2JJB9|A0A0G2JJB9_HUMAN,tr|H0YGW7|H0YGW7_HUMAN" 4 1983.8592 0.84 67293 15770 3 1983.860768 662.2937 ATP-binding cassette sub-family F member 1 OS=Homo sapiens OX=9606 GN=ABCF1 PE=1 SV=2 4.14 2788.1 - 1.01E+06 - - - 0.7737 - 3.492 0.658 - 310.8 1 2 0 0.0015 19 0 0 0 6.53E+06 7.79E+06 - - - 8.9478 1 221125_WJC_METTL3_EV_vs_WT_F05.15771.15771.2 8.55E-11 15/36 R.SADAGSFSPTPGQIGGAVK[136.11].L sp|O00443|P3C2A_HUMAN 1 1753.8726 1.66 67294 15771 2 1753.870082 877.9436 Phosphatidylinositol 4-phosphate 3-kinase C2 domain-containing subunit alpha OS=Homo sapiens OX=9606 GN=PIK3C2A PE=1 SV=2 5.55 2788.3 - 904298 - - - -1.4516 - 3.19 0.644 - 478.9 1 2 0 -0.0025 19 0 0 0 1.94E+07 1.17E+07 - - - 6.6487 0.9999 221125_WJC_METTL3_EV_vs_WT_F05.15774.15774.3 0.0141 14/36 K.KQELLEALTK.H "sp|P12956|XRCC6_HUMAN,tr|B1AHC9|B1AHC9_HUMAN" 2 1171.6812 1.12 67297 15774 3 1171.68076 391.5677 X-ray repair cross-complementing protein 6 OS=Homo sapiens OX=9606 GN=XRCC6 PE=1 SV=2 6.14 2788.6 - 752736 - - - -0.4088 - 2.796 0.348 - 242 1 2 0 -0.0005 10 0 0 0 1.87E+07 1.67E+07 - - - 5.4225 0.9999 221125_WJC_METTL3_EV_vs_WT_F05.15775.15775.3 0.000178 Dec-44 R.DAGLSFKDDMPK.S "sp|Q9NW64|RBM22_HUMAN,tr|E5RJW4|E5RJW4_HUMAN,tr|E5RHA8|E5RHA8_HUMAN" 3 1322.6177 0.64 67298 15775 3 1322.617272 441.8798 Pre-mRNA-splicing factor RBM22 OS=Homo sapiens OX=9606 GN=RBM22 PE=1 SV=1 4.43 2788.8 - 575753 - - - -0.2873 - 2.162 0.564 - 183 1 2 1 -0.0004 12 0 0 0 9.60E+06 1.51E+07 - - - 6.9651 0.9996 221125_WJC_METTL3_EV_vs_WT_F05.15778.15778.2 4.40E-05 22-Sep R.NNSGEEFDC[160.03]AFR[166.11].L sp|Q08J23|NSUN2_HUMAN 1 1454.576 1.1 67301 15778 2 1454.580238 728.2953 RNA cytosine C(5)-methyltransferase NSUN2 OS=Homo sapiens OX=9606 GN=NSUN2 PE=1 SV=2 4.14 2789.1 - 259510 - - - 2.9053 - 2.069 0.621 - 219.6 1 2 0 0.0042 12 0 0 0 1.47E+07 1.34E+07 - - - 5.5394 1 221125_WJC_METTL3_EV_vs_WT_F05.15783.15783.3 0.00091 15/44 K.MQLLQSLQEQKK.E "sp|Q15643|TRIPB_HUMAN,tr|H0YJ97|H0YJ97_HUMAN" 2 1472.8021 1.04 67305 15783 3 1472.8023 491.9413 Thyroid receptor-interacting protein 11 OS=Homo sapiens OX=9606 GN=TRIP11 PE=1 SV=3 8.35 2789.6 - 1.84E+06 - - - 0.1365 - 2.886 0.407 - 350.3 1 2 0 0.0002 12 0 0 0 1.61E+07 1.55E+07 - - - 6.0154 1 221125_WJC_METTL3_EV_vs_WT_F05.15784.15784.3 1.82E-09 17/60 R.FDAERPVDC[160.03]SVIVVNK.Q "sp|Q9HCD5|NCOA5_HUMAN,tr|Q5JY17|Q5JY17_HUMAN" 2 1846.9247 1.74 67306 15784 3 1846.924218 616.6489 Nuclear receptor coactivator 5 OS=Homo sapiens OX=9606 GN=NCOA5 PE=1 SV=2 4.56 2789.8 - 977167 - - - -0.2794 - 3.467 0.617 - 390.7 1 2 0 -0.0005 16 0 0 0 2.90E+07 1.67E+07 - - - 8.6089 0.9999 221125_WJC_METTL3_EV_vs_WT_F05.15785.15785.3 2.96E-06 15/68 K.YGQFSGLNPGGR[166.11]PITPPR[166.11].N "sp|P62136|PP1A_HUMAN,tr|A0A7I2V4F7|A0A7I2V4F7_HUMAN,tr|E9PMD7|E9PMD7_HUMAN" 3 1933.0073 2.61 67307 15785 3 1933.005705 645.343 Serine\threonine-protein phosphatase PP1-alpha catalytic subunit OS=Homo sapiens OX=9606 GN=PPP1CA PE=1 SV=1 10.84 2789.9 - 904217 - - - -0.8355 - 2.408 0.421 - 288.1 1 2 0 -0.0016 18 0 0 0 7.46E+06 2.86E+06 - - - 5.4216 0.9715 221125_WJC_METTL3_EV_vs_WT_F05.15786.15786.4 0.00153 15/96 L.LQDDAHPTLVTYADHSK[136.11].L "sp|Q86U44|MTA70_HUMAN,tr|F5H6D8|F5H6D8_HUMAN,tr|H0YFV6|H0YFV6_HUMAN,tr|B4DTN4|B4DTN4_HUMAN" 4 1917.9312 0.02 67308 15786 4 1917.928454 480.4901 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 5.13 2790 - 793974 - - - -1.4349 - 2.197 0.369 - 141.2 1 1 0 -0.0028 17 0 0 0 7.06E+04 4.15E+06 - - - 2.7103 0.9826 221125_WJC_METTL3_EV_vs_WT_F05.15787.15787.3 1.34E-05 Dec-56 Q.DDAHPTLVTYADHSK[136.11].L "sp|Q86U44|MTA70_HUMAN,tr|F5H6D8|F5H6D8_HUMAN,tr|H0YFV6|H0YFV6_HUMAN,tr|B4DTN4|B4DTN4_HUMAN" 4 1676.7886 0.001 67309 15787 3 1676.782808 559.9368 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 5.13 2790.1 - 485971 - - - -3.4328 - 2.175 0.523 - 164 1 1 0 -0.0058 15 0 0 0 0.00E+00 3.00E+06 - - - 6.3969 1 221125_WJC_METTL3_EV_vs_WT_F05.15788.15788.2 2.49E-09 22-Dec R.NNSGEEFDC[160.03]AFR.L sp|Q08J23|NSUN2_HUMAN 1 1444.5677 1.1 67310 15788 2 1444.562789 723.2911 RNA cytosine C(5)-methyltransferase NSUN2 OS=Homo sapiens OX=9606 GN=NSUN2 PE=1 SV=2 4.14 2790.2 - 442143 - - - -3.4287 - 2.665 0.763 - 845.4 1 2 0 -0.005 12 0 0 0 1.47E+07 1.34E+07 - - - 7.254 0.8292 221125_WJC_METTL3_EV_vs_WT_F05.15796.15796.3 0.021 Nov-72 R.LLEGEDAHLSSSQFSSGSQ.S sp|P02533|K1C14_HUMAN 1 1977.8916 - 67317 15796 3 1977.896923 660.3045 "Keratin, type I cytoskeletal 14 OS=Homo sapiens OX=9606 GN=KRT14 PE=1 SV=4" 4.13 2791.1 - 1.08E+06 - - - 2.7019 - 1.892 0.318 - 96.8 1 1 0 0.0053 19 0 0 0 - - - - - 3.6504 0.9997 221125_WJC_METTL3_EV_vs_WT_F05.15797.15797.3 0.00022 18/44 R.TK[136.11]EIEAIHAILR[166.11].S sp|Q15643|TRIPB_HUMAN 1 1410.8314 1.24 67318 15797 3 1410.826733 471.2844 Thyroid receptor-interacting protein 11 OS=Homo sapiens OX=9606 GN=TRIP11 PE=1 SV=3 6.42 2791.2 - 803534 - - - -3.286 - 2.991 0.544 - 404.4 1 2 1 -0.0046 12 0 0 0 2.14E+07 1.73E+07 - - - 7.6406 1 221125_WJC_METTL3_EV_vs_WT_F05.15798.15798.2 4.58E-07 Dec-36 R.LLEGEDAHLSSSQFSSGSQ.S sp|P02533|K1C14_HUMAN 1 1977.8916 - 67319 15798 2 1977.889544 989.9531 "Keratin, type I cytoskeletal 14 OS=Homo sapiens OX=9606 GN=KRT14 PE=1 SV=4" 4.13 2791.4 - 620591 - - - -1.0289 - 3.004 0.656 - 286.2 1 1 0 -0.002 19 0 0 0 - - - - - 6.5898 0.9995 221125_WJC_METTL3_EV_vs_WT_F05.15799.15799.3 0.00868 Nov-40 K.QLQEIFENYK[136.11]K[136.11].E sp|P12270|TPR_HUMAN 1 1454.774 3.39 67320 15799 3 1454.775264 485.932 Nucleoprotein TPR OS=Homo sapiens OX=9606 GN=TPR PE=1 SV=3 6.14 2791.5 - 564270 - - - 0.8482 - 2.12 0.281 - 132.8 1 2 0 0.0012 11 0 0 0 3.78E+07 1.12E+07 - - - 3.8072 0.9651 221125_WJC_METTL3_EV_vs_WT_F05.15802.15802.3 0.0498 Oct-44 K.NK[136.11]EPGEIQYLIK[136.11].W sp|O14646|CHD1_HUMAN 1 1446.8053 4.18 67323 15802 3 1446.801079 483.2757 Chromodomain-helicase-DNA-binding protein 1 OS=Homo sapiens OX=9606 GN=CHD1 PE=1 SV=2 6.14 2791.9 - 310463 - - - -2.9382 - 1.637 0.257 - 90.6 1 2 1 -0.0043 12 0 0 0 8.29E+06 1.98E+06 - - - 2.7703 0.9993 221125_WJC_METTL3_EV_vs_WT_F05.15806.15806.3 0.0278 13/40 K.QLQEIFENYKK.E sp|P12270|TPR_HUMAN 1 1438.7456 3.4 67325 15806 3 1438.74539 480.5892 Nucleoprotein TPR OS=Homo sapiens OX=9606 GN=TPR PE=1 SV=3 6.14 2792.4 - 2.84E+06 - - - -0.1668 - 2.025 0.27 - 249.1 1 2 0 -0.0002 11 0 0 0 3.80E+07 1.12E+07 - - - 3.5546 0.9035 221125_WJC_METTL3_EV_vs_WT_F05.15808.15808.3 0.747 13/44 L.RLSVEADINGLR.R "sp|Q04695|K1C17_HUMAN,tr|F5GWP8|F5GWP8_HUMAN" 2 1341.7365 8.09 67327 15808 3 1341.73616 448.2528 "Keratin, type I cytoskeletal 17 OS=Homo sapiens OX=9606 GN=KRT17 PE=1 SV=2" 6.07 2792.5 - 2.28E+06 - - - -0.2251 - 2.318 0.218 - 296.5 1 1 0 -0.0003 12 0 0 0 2.59E+07 3.20E+06 - - - 3.3007 0.9999 221125_WJC_METTL3_EV_vs_WT_F05.15810.15810.3 7.66E-08 18/44 R.TKEIEAIHAILR.S sp|Q15643|TRIPB_HUMAN 1 1392.8089 1.24 67329 15810 3 1392.807471 465.2769 Thyroid receptor-interacting protein 11 OS=Homo sapiens OX=9606 GN=TRIP11 PE=1 SV=3 6.42 2792.8 - 1.04E+06 - - - -1.0253 - 3.211 0.541 - 485.8 1 2 1 -0.0014 12 0 0 0 2.14E+07 1.73E+07 - - - 7.8048 0.9999 221125_WJC_METTL3_EV_vs_WT_F05.15811.15811.2 4.21E-08 13/20 K.QQIQNDLNQWK.T sp|P15924|DESP_HUMAN 1 1413.7001 22.53 67330 15811 2 1413.700207 707.8573 Desmoplakin OS=Homo sapiens OX=9606 GN=DSP PE=1 SV=3 5.84 2792.9 - 875645 - - - 0.092 - 2.578 0.548 - 793.8 1 2 0 0.0001 11 0 0 0 8.55E+07 3.79E+06 - - - 5.6504 1 221125_WJC_METTL3_EV_vs_WT_F05.15812.15812.3 1.40E-05 19/48 R.LLEEQLQHEISNK.M sp|Q86UP2|KTN1_HUMAN 1 1579.8206 2.16 67331 15812 3 1579.818202 527.6141 Kinectin OS=Homo sapiens OX=9606 GN=KTN1 PE=1 SV=1 4.75 2793 - 798511 - - - -1.509 - 2.902 0.481 - 457.5 1 2 0 -0.0024 13 0 0 0 2.37E+07 1.10E+07 - - - 6.7906 0.9999 221125_WJC_METTL3_EV_vs_WT_F05.15813.15813.3 1.32E-05 13/48 R.LLEEQLQHEISNK[136.11].M sp|Q86UP2|KTN1_HUMAN 1 1587.8348 2.16 67332 15813 3 1587.831943 530.2855 Kinectin OS=Homo sapiens OX=9606 GN=KTN1 PE=1 SV=1 4.75 2793.2 - 664218 - - - -1.7905 - 2.6 0.449 - 198.8 1 2 0 -0.0028 13 0 0 0 2.37E+07 1.10E+07 - - - 6.1358 1 221125_WJC_METTL3_EV_vs_WT_F05.15814.15814.2 6.85E-12 17/38 F.GGFGGGAGGGDGGILTANEK.S sp|P35527|K1C9_HUMAN 1 1690.7911 999 67333 15814 2 1690.785976 846.4028 "Keratin, type I cytoskeletal 9 OS=Homo sapiens OX=9606 GN=KRT9 PE=1 SV=3" 4.37 2793.3 - 607052 - - - -3.0169 - 3.598 0.706 - 755.3 1 1 0 -0.0051 20 0 0 0 3.77E+07 0.00E+00 - - - 7.4018 0.9999 221125_WJC_METTL3_EV_vs_WT_F05.15816.15816.2 1.54E-05 Dec-36 R.GLLQDDAHPTLVTYADHSK[136.11].L "sp|Q86U44|MTA70_HUMAN,tr|F5H6D8|F5H6D8_HUMAN,tr|H0YFV6|H0YFV6_HUMAN,tr|B4DTN4|B4DTN4_HUMAN" 4 2088.0367 0.001 67335 15816 2 2088.037376 1045.0256 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 5.13 2793.6 - 546387 - - - 0.3079 - 2.655 0.565 - 289.8 1 2 0 0.0006 19 0 0 0 0.00E+00 5.22E+06 - - - 5.6145 1 221125_WJC_METTL3_EV_vs_WT_F05.15818.15818.2 4.78E-11 Dec-32 R.WNSPAEEGSSDC[160.03]EVFSK[136.11].N "sp|P34932|HSP74_HUMAN,tr|A0A087WTS8|A0A087WTS8_HUMAN,tr|A0A087WYC1|A0A087WYC1_HUMAN" 3 1935.8036 0.08 67337 15818 2 1935.80307 968.9091 Heat shock 70 kDa protein 4 OS=Homo sapiens OX=9606 GN=HSPA4 PE=1 SV=4 4 2793.8 - 357718 - - - -0.2852 - 3.029 0.76 - 409.6 1 2 0 -0.0006 17 0 0 0 5.94E+06 7.42E+07 - - - 7.3788 1 221125_WJC_METTL3_EV_vs_WT_F05.15821.15821.2 1.49E-12 21/34 R.VDSAATSGYEIGNPPDYR.G "sp|P24666|PPAC_HUMAN,tr|G5E9R5|G5E9R5_HUMAN" 2 1910.8646 1.07 67339 15821 2 1910.864549 956.4396 Low molecular weight phosphotyrosine protein phosphatase OS=Homo sapiens OX=9606 GN=ACP1 PE=1 SV=3 4.03 2794.2 - 1.65E+06 - - - -0.0455 - 3.253 0.713 - 1071.2 1 2 0 -0.0001 18 0 0 0 1.67E+07 1.56E+07 - - - 7.2072 0.9998 221125_WJC_METTL3_EV_vs_WT_F05.15823.15823.3 1.28E-07 16/56 K.DVDAAYMNKVELQAK.A "sp|P48668|K2C6C_HUMAN,sp|P04259|K2C6B_HUMAN,sp|Q14CN4|K2C72_HUMAN,sp|P02538|K2C6A_HUMAN" 4 1693.8345 112.02 67341 15823 3 1693.829212 565.6188 "Keratin, type II cytoskeletal 6C OS=Homo sapiens OX=9606 GN=KRT6C PE=1 SV=3" 4.56 2794.3 - 4.23E+06 - - - -3.1349 - 3.028 0.614 - 207.6 1 2 1 -0.0053 15 0 0 0 1.60E+08 1.43E+06 - - - 8.2749 1 221125_WJC_METTL3_EV_vs_WT_F05.15824.15824.3 3.85E-09 18/72 R.VNSGLSSDPHFEEPGPMVR.G sp|P48634|PRC2A_HUMAN 1 2053.9527 1.23 67342 15824 3 2053.953771 685.6582 Protein PRRC2A OS=Homo sapiens OX=9606 GN=PRRC2A PE=1 SV=3 4.65 2794.4 - 1.95E+06 - - - 0.5024 - 3.06 0.622 - 371.2 1 2 0 0.001 19 0 0 0 1.28E+07 1.04E+07 - - - 8.2221 0.9998 221125_WJC_METTL3_EV_vs_WT_F05.15826.15826.3 3.64E-07 15/64 K.TAASGIPYHSEVPVSLK[136.11].E "sp|Q01082|SPTB2_HUMAN,tr|A0A087WUZ3|A0A087WUZ3_HUMAN" 2 1762.9345 1.99 67344 15826 3 1762.942217 588.6521 "Spectrin beta chain, non-erythrocytic 1 OS=Homo sapiens OX=9606 GN=SPTBN1 PE=1 SV=2" 6.41 2794.5 - 1.61E+06 - - - 4.3774 - 2.601 0.542 - 203 1 2 0 0.0077 17 0 0 0 2.43E+07 1.22E+07 - - - 6.9955 0.9893 221125_WJC_METTL3_EV_vs_WT_F05.15827.15827.3 2.08E-06 14/60 L.QDDAHPTLVTYADHSK[136.11].L "sp|Q86U44|MTA70_HUMAN,tr|F5H6D8|F5H6D8_HUMAN,tr|H0YFV6|H0YFV6_HUMAN,tr|B4DTN4|B4DTN4_HUMAN" 4 1804.8471 0.001 67345 15827 3 1804.841517 602.623 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 5.13 2794.6 - 1.21E+06 - - - -3.1166 - 2.461 0.528 - 248.5 1 1 0 -0.0056 16 0 0 0 0.00E+00 8.69E+06 - - - 6.7359 1 221125_WJC_METTL3_EV_vs_WT_F05.15829.15829.3 7.84E-09 20/76 R.VLQAQGSSDPEEESVLYSNR.A sp|Q15785|TOM34_HUMAN 1 2207.0342 1.46 67347 15829 3 2207.033974 736.6853 Mitochondrial import receptor subunit TOM34 OS=Homo sapiens OX=9606 GN=TOMM34 PE=1 SV=2 4 2794.9 - 1.08E+06 - - - -0.1115 - 3.649 0.679 - 402.5 1 2 0 -0.0002 20 0 0 0 8.52E+06 5.83E+06 - - - 9.2505 0.9978 221125_WJC_METTL3_EV_vs_WT_F05.15830.15830.3 5.41E-06 Oct-48 K.WK[136.11]DSDEADLVLAK[136.11].E sp|Q13185|CBX3_HUMAN 1 1504.7744 0.82 67348 15830 3 1504.772752 502.5988 Chromobox protein homolog 3 OS=Homo sapiens OX=9606 GN=CBX3 PE=1 SV=4 4.23 2795 - 738081 - - - -1.1111 - 2.226 0.285 - 146.1 1 2 1 -0.0017 13 0 0 0 6.82E+06 8.27E+06 - - - 3.8866 1 221125_WJC_METTL3_EV_vs_WT_F05.15831.15831.3 4.07E-12 23/76 R.VLQAQGSSDPEEESVLYSNR[166.11].A sp|Q15785|TOM34_HUMAN 1 2217.0425 1.46 67349 15831 3 2217.042836 740.0214 Mitochondrial import receptor subunit TOM34 OS=Homo sapiens OX=9606 GN=TOMM34 PE=1 SV=2 4 2795.1 - 636966 - - - 0.1561 - 3.875 0.688 - 674.3 1 2 0 0.0003 20 0 0 0 8.52E+06 5.83E+06 - - - 9.4966 1 221125_WJC_METTL3_EV_vs_WT_F05.15841.15841.3 9.85E-10 13/68 R.VDSAATSGYEIGNPPDYR.G "sp|P24666|PPAC_HUMAN,tr|G5E9R5|G5E9R5_HUMAN" 2 1910.8646 1.17 67358 15841 3 1910.864496 637.9622 Low molecular weight phosphotyrosine protein phosphatase OS=Homo sapiens OX=9606 GN=ACP1 PE=1 SV=3 4.03 2796.3 - 2.34E+06 - - - -0.0733 - 2.731 0.617 - 194.7 1 2 0 -0.0001 18 0 0 0 1.95E+07 1.67E+07 - - - 7.9206 1 221125_WJC_METTL3_EV_vs_WT_F05.15842.15842.3 5.92E-07 14/68 R.VDSAATSGYEIGNPPDYR[166.11].G "sp|P24666|PPAC_HUMAN,tr|G5E9R5|G5E9R5_HUMAN" 2 1920.8729 1.17 67359 15842 3 1920.87183 641.2982 Low molecular weight phosphotyrosine protein phosphatase OS=Homo sapiens OX=9606 GN=ACP1 PE=1 SV=3 4.03 2796.3 - 1.85E+06 - - - -0.5602 - 2.688 0.574 - 217.3 1 2 0 -0.0011 18 0 0 0 1.95E+07 1.67E+07 - - - 7.4014 1 221125_WJC_METTL3_EV_vs_WT_F05.15844.15844.2 1.95E-12 22/34 R.VDSAATSGYEIGNPPDYR[166.11].G "sp|P24666|PPAC_HUMAN,tr|G5E9R5|G5E9R5_HUMAN" 2 1920.8729 1.26 67361 15844 2 1920.873717 961.4437 Low molecular weight phosphotyrosine protein phosphatase OS=Homo sapiens OX=9606 GN=ACP1 PE=1 SV=3 4.03 2796.5 - 1.79E+06 - - - 0.4222 - 3.784 0.714 - 1283.7 1 2 0 0.0008 18 0 0 0 2.18E+07 1.73E+07 - - - 7.5861 1 221125_WJC_METTL3_EV_vs_WT_F05.15845.15845.3 1.39E-08 14/52 K.NMQNVEHVPLSLDR[166.11].A sp|P20618|PSB1_HUMAN 1 1660.8231 0.98 67362 15845 3 1660.822502 554.615 Proteasome subunit beta type-1 OS=Homo sapiens OX=9606 GN=PSMB1 PE=1 SV=2 5.32 2796.6 - 1.18E+06 - - - -0.3354 - 2.678 0.588 - 206.2 1 2 0 -0.0006 14 0 0 0 1.33E+07 1.36E+07 - - - 7.7133 1 221125_WJC_METTL3_EV_vs_WT_F05.15846.15846.3 5.92E-11 22/56 R.GPSLNPVLDYDHGSR.S "sp|P43243|MATR3_HUMAN,tr|A8MXP9|A8MXP9_HUMAN,tr|D6R991|D6R991_HUMAN,tr|A0A0R4J2E8|A0A0R4J2E8_HUMAN,tr|D6REM6|D6REM6_HUMAN" 5 1625.7798 1.48 67363 15846 3 1625.779251 542.9339 Matrin-3 OS=Homo sapiens OX=9606 GN=MATR3 PE=1 SV=2 5.21 2796.7 - 1.04E+06 - - - -0.3278 - 3.54 0.666 - 954.8 1 2 0 -0.0005 15 0 0 0 2.07E+09 1.39E+09 - - - 9.2637 0.9998 221125_WJC_METTL3_EV_vs_WT_F05.15847.15847.3 2.41E-05 Dec-48 K.WKDSDEADLVLAK.E sp|Q13185|CBX3_HUMAN 1 1488.746 0.76 67364 15847 3 1488.744813 497.256 Chromobox protein homolog 3 OS=Homo sapiens OX=9606 GN=CBX3 PE=1 SV=4 4.23 2796.8 - 836726 - - - -0.8134 - 2.632 0.456 - 248.1 1 2 1 -0.0012 13 0 0 0 6.02E+06 7.90E+06 - - - 6.2474 0.9995 221125_WJC_METTL3_EV_vs_WT_F05.15848.15848.3 7.31E-05 Oct-44 K.GKLDVQFSGLTK.G "sp|P21333|FLNA_HUMAN,tr|A0A7P0NMY4|A0A7P0NMY4_HUMAN,tr|Q60FE5|Q60FE5_HUMAN" 3 1291.7136 1 67365 15848 3 1291.714181 431.5785 Filamin-A OS=Homo sapiens OX=9606 GN=FLNA PE=1 SV=4 8.59 2796.9 - 536968 - - - 0.4482 - 1.959 0.424 - 126.1 1 2 1 0.0006 12 0 0 0 8.02E+06 7.99E+06 - - - 5.1309 0.9997 221125_WJC_METTL3_EV_vs_WT_F05.15849.15849.3 0.000241 Nov-44 K.GK[136.11]LDVQFSGLTK[136.11].G "sp|P21333|FLNA_HUMAN,tr|A0A7P0NMY4|A0A7P0NMY4_HUMAN,tr|Q60FE5|Q60FE5_HUMAN" 3 1307.742 1 67366 15849 3 1307.742692 436.9213 Filamin-A OS=Homo sapiens OX=9606 GN=FLNA PE=1 SV=4 8.59 2797 - 455433 - - - 0.5276 - 2.234 0.451 - 163.5 1 2 1 0.0007 12 0 0 0 7.96E+06 7.99E+06 - - - 5.796 0.9999 221125_WJC_METTL3_EV_vs_WT_F05.15850.15850.2 1.52E-06 24-Sep R.FSGSGSGTDFTLK.L "sp|A2NJV5|KV229_HUMAN,sp|A0A087WW87|KV240_HUMAN,sp|P06310|KV230_HUMAN,sp|A0A075B6S2|KVD29_HUMAN,sp|P01614|KVD40_HUMAN,sp|P01615|KVD28_HUMAN,sp|A0A075B6S6|KVD30_HUMAN,sp|A0A075B6P5|KV228_HUMAN,sp|A0A0A0MRZ7|KVD26_HUMAN" 9 1302.6092 999 67367 15850 2 1302.609541 652.3119 Immunoglobulin kappa variable 2-29 OS=Homo sapiens OX=9606 GN=IGKV2-29 PE=3 SV=2 5.84 2797.2 - 394354 - - - 0.2649 - 2.161 0.6 - 136.9 1 2 0 0.0003 13 0 0 0 3.83E+06 0.00E+00 - - - 5.4502 1 221125_WJC_METTL3_EV_vs_WT_F05.15851.15851.2 6.93E-05 14/24 R.LLEEQLQHEISNK.M sp|Q86UP2|KTN1_HUMAN 1 1579.8206 3.48 67368 15851 2 1579.822438 790.9176 Kinectin OS=Homo sapiens OX=9606 GN=KTN1 PE=1 SV=1 4.75 2797.3 - 342660 - - - 1.1723 - 3.049 0.577 - 677.4 1 2 0 0.0019 13 0 0 0 2.59E+06 7.44E+05 - - - 6.1633 0.9998 221125_WJC_METTL3_EV_vs_WT_F05.15854.15854.2 0.000332 24-Oct R.LLEEQLQHEISNK[136.11].M sp|Q86UP2|KTN1_HUMAN 1 1587.8348 -1 67371 15854 2 1587.836785 794.9247 Kinectin OS=Homo sapiens OX=9606 GN=KTN1 PE=1 SV=1 4.75 2797.7 - 235026 - - - 1.2589 - 2.136 0.459 - 294 1 2 0 0.002 13 0 0 0 0.00E+00 0.00E+00 - - - 4.3784 1 221125_WJC_METTL3_EV_vs_WT_F05.15857.15857.3 3.25E-07 Oct-60 R.FDAER[166.11]PVDC[160.03]SVIVVNK[136.11].Q "sp|Q9HCD5|NCOA5_HUMAN,tr|Q5JY17|Q5JY17_HUMAN" 2 1864.9472 1.74 67373 15857 3 1864.949102 622.6563 Nuclear receptor coactivator 5 OS=Homo sapiens OX=9606 GN=NCOA5 PE=1 SV=2 4.56 2798 - 917893 - - - 1.0177 - 2.396 0.524 - 139 1 2 0 0.0019 16 0 0 0 2.90E+07 1.67E+07 - - - 6.6236 1 221125_WJC_METTL3_EV_vs_WT_F05.15859.15859.3 1.90E-05 Dec-52 K.LTFDTTFSPNTGKK.S "sp|P45880|VDAC2_HUMAN,tr|Q5JSD1|Q5JSD1_HUMAN,tr|Q5JSD2|Q5JSD2_HUMAN,tr|A0A0A0MR02|A0A0A0MR02_HUMAN" 4 1555.7882 1.21 67375 15859 3 1555.790778 519.6034 Voltage-dependent anion-selective channel protein 2 OS=Homo sapiens OX=9606 GN=VDAC2 PE=1 SV=2 8.59 2798.2 - 4.53E+06 - - - 1.6423 - 2.436 0.546 - 156.6 1 2 0 0.0026 14 0 0 0 8.07E+07 6.69E+07 - - - 6.9928 1 221125_WJC_METTL3_EV_vs_WT_F05.15860.15860.3 3.27E-08 16/56 R.GPSLNPVLDYDHGSR[166.11].S "sp|P43243|MATR3_HUMAN,tr|A8MXP9|A8MXP9_HUMAN,tr|D6R991|D6R991_HUMAN,tr|A0A0R4J2E8|A0A0R4J2E8_HUMAN,tr|D6REM6|D6REM6_HUMAN" 5 1635.7881 1.48 67376 15860 3 1635.788019 546.27 Matrin-3 OS=Homo sapiens OX=9606 GN=MATR3 PE=1 SV=2 5.21 2798.2 - 4.37E+06 - - - -0.0214 - 3.282 0.603 - 367.8 1 2 0 0 15 0 0 0 2.07E+09 1.39E+09 - - - 8.364 1 221125_WJC_METTL3_EV_vs_WT_F05.15861.15861.4 2.36E-08 22/108 R.VIHLSNLPHSGYSDSAVLK.L "sp|P43243|MATR3_HUMAN,tr|B3KM87|B3KM87_HUMAN,tr|A8MXP9|A8MXP9_HUMAN,tr|D6RBK5|D6RBK5_HUMAN,tr|A0A0R4J2E8|A0A0R4J2E8_HUMAN,tr|H0Y8T4|H0Y8T4_HUMAN,tr|D6REM6|D6REM6_HUMAN" 7 2036.0691 1.39 67377 15861 4 2036.072252 510.0245 Matrin-3 OS=Homo sapiens OX=9606 GN=MATR3 PE=1 SV=2 6.89 2798.3 - 3.28E+06 - - - 1.553 - 3.971 0.536 - 450.4 1 2 0 0.0032 19 0 0 0 8.22E+08 5.93E+08 - - - 4.357 1 221125_WJC_METTL3_EV_vs_WT_F05.15862.15862.4 4.28E-09 21/108 R.VIHLSNLPHSGYSDSAVLK[136.11].L "sp|P43243|MATR3_HUMAN,tr|B3KM87|B3KM87_HUMAN,tr|A8MXP9|A8MXP9_HUMAN,tr|D6RBK5|D6RBK5_HUMAN,tr|A0A0R4J2E8|A0A0R4J2E8_HUMAN,tr|H0Y8T4|H0Y8T4_HUMAN,tr|D6REM6|D6REM6_HUMAN" 7 2044.0833 1.39 67378 15862 4 2044.08559 512.0281 Matrin-3 OS=Homo sapiens OX=9606 GN=MATR3 PE=1 SV=2 6.89 2798.3 - 3.26E+06 - - - 1.1252 - 3.834 0.568 - 395.6 1 2 0 0.0023 19 0 0 0 8.22E+08 5.93E+08 - - - 4.6239 0.9999 221125_WJC_METTL3_EV_vs_WT_F05.15863.15863.3 0.000332 13/52 K.NMQNVEHVPLSLDR.A sp|P20618|PSB1_HUMAN 1 1650.8148 0.97 67379 15863 3 1650.817304 551.2789 Proteasome subunit beta type-1 OS=Homo sapiens OX=9606 GN=PSMB1 PE=1 SV=2 5.32 2798.4 - 1.68E+06 - - - 1.5235 - 2.327 0.433 - 191.2 1 2 0 0.0025 14 0 0 0 1.33E+07 1.37E+07 - - - 5.6113 0.9993 221125_WJC_METTL3_EV_vs_WT_F05.15866.15866.2 0.00145 20-Oct K.QQIQNDLNQWK[136.11].T sp|P15924|DESP_HUMAN 1 1421.7143 22.53 67382 15866 2 1421.716618 711.8644 Desmoplakin OS=Homo sapiens OX=9606 GN=DSP PE=1 SV=3 5.84 2798.7 - 488777 - - - 1.6466 - 1.889 0.358 - 293.4 1 2 0 0.0023 11 0 0 0 8.55E+07 3.79E+06 - - - 3.4051 0.9966 221125_WJC_METTL3_EV_vs_WT_F05.15867.15867.3 4.92E-07 15/44 K.HSDVLFLAVKPH.L "sp|Q96C36|P5CR2_HUMAN,tr|A0A087WX69|A0A087WX69_HUMAN,tr|A0A087WZF0|A0A087WZF0_HUMAN,tr|A0A087WTV6|A0A087WTV6_HUMAN,tr|J3KR12|J3KR12_HUMAN" 5 1361.7456 0.84 67383 15867 3 1361.742666 454.9225 Pyrroline-5-carboxylate reductase 2 OS=Homo sapiens OX=9606 GN=PYCR2 PE=1 SV=1 6.92 2798.8 - 374691 - - - -2.1333 - 2.637 0.553 - 304.5 1 1 0 -0.0029 12 0 0 0 3.75E+06 4.44E+06 - - - 7.3923 0.9985 221125_WJC_METTL3_EV_vs_WT_F05.15869.15869.3 4.14E-05 17/72 K.PSTASAVPELATDPELEK[136.11]K[136.11].L "sp|Q86U44|MTA70_HUMAN,tr|B4E349|B4E349_HUMAN,tr|F5H6D8|F5H6D8_HUMAN,tr|H0YFV6|H0YFV6_HUMAN,tr|B4DTN4|B4DTN4_HUMAN" 5 1998.0492 0.001 67385 15869 3 1998.048146 667.0237 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 4.41 2799.1 - 258762 - - - -0.5285 - 2.85 0.584 - 304.1 1 1 0 -0.0011 19 0 0 0 0.00E+00 1.20E+06 - - - 7.6238 1 221125_WJC_METTL3_EV_vs_WT_F05.15870.15870.2 5.81E-11 Oct-38 R.FSSC[160.03]GGGGGSFGAGGGFGSR.S sp|P04264|K2C1_HUMAN 1 1764.7274 -1 67386 15870 2 1764.723259 883.371 "Keratin, type II cytoskeletal 1 OS=Homo sapiens OX=9606 GN=KRT1 PE=1 SV=6" 8.25 2799.2 - 110709 - - - -2.3641 - 2.542 0.773 - 199.9 1 2 0 -0.0042 20 0 0 0 0.00E+00 0.00E+00 - - - 7.0428 0.9999 221125_WJC_METTL3_EV_vs_WT_F05.15873.15873.4 0.000646 10/108 R.GLLQDDAHPTLVTYADHSK[136.11].L "sp|Q86U44|MTA70_HUMAN,tr|F5H6D8|F5H6D8_HUMAN,tr|H0YFV6|H0YFV6_HUMAN,tr|B4DTN4|B4DTN4_HUMAN" 4 2088.0367 0.02 67387 15873 4 2088.03674 523.0165 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 5.13 2799.6 - 7.93E+06 - - - 0.0034 - 2.073 0.453 - 86.4 1 2 0 0 19 0 0 0 2.01E+07 8.77E+08 - - - 3.4155 1 221125_WJC_METTL3_EV_vs_WT_F05.15874.15874.3 3.30E-08 26/72 R.VIHLSNLPHSGYSDSAVLK.L "sp|P43243|MATR3_HUMAN,tr|B3KM87|B3KM87_HUMAN,tr|A8MXP9|A8MXP9_HUMAN,tr|D6RBK5|D6RBK5_HUMAN,tr|A0A0R4J2E8|A0A0R4J2E8_HUMAN,tr|H0Y8T4|H0Y8T4_HUMAN,tr|D6REM6|D6REM6_HUMAN" 7 2036.0691 1.42 67388 15874 3 2036.069967 679.697 Matrin-3 OS=Homo sapiens OX=9606 GN=MATR3 PE=1 SV=2 6.89 2799.7 - 4.14E+06 - - - 0.4307 - 4.387 0.644 - 904.6 1 2 0 0.0009 19 0 0 0 3.06E+08 2.16E+08 - - - 9.3525 1 221125_WJC_METTL3_EV_vs_WT_F05.15875.15875.3 4.05E-08 22/72 R.VIHLSNLPHSGYSDSAVLK[136.11].L "sp|P43243|MATR3_HUMAN,tr|B3KM87|B3KM87_HUMAN,tr|A8MXP9|A8MXP9_HUMAN,tr|D6RBK5|D6RBK5_HUMAN,tr|A0A0R4J2E8|A0A0R4J2E8_HUMAN,tr|H0Y8T4|H0Y8T4_HUMAN,tr|D6REM6|D6REM6_HUMAN" 7 2044.0833 1.43 67389 15875 3 2044.084472 682.3684 Matrin-3 OS=Homo sapiens OX=9606 GN=MATR3 PE=1 SV=2 6.89 2799.7 - 2.92E+06 - - - 0.5783 - 3.896 0.635 - 595 1 2 0 0.0012 19 0 0 0 3.08E+08 2.16E+08 - - - 8.9604 0.9998 221125_WJC_METTL3_EV_vs_WT_F05.15879.15879.2 0.000851 13/28 R.GPSLNPVLDYDHGSR.S "sp|P43243|MATR3_HUMAN,tr|A8MXP9|A8MXP9_HUMAN,tr|D6R991|D6R991_HUMAN,tr|A0A0R4J2E8|A0A0R4J2E8_HUMAN,tr|D6REM6|D6REM6_HUMAN" 5 1625.7798 1.59 67393 15879 2 1625.782204 813.8972 Matrin-3 OS=Homo sapiens OX=9606 GN=MATR3 PE=1 SV=2 5.21 2800 - 549252 - - - 1.4885 - 2.62 0.555 - 448.2 1 2 0 0.0024 15 0 0 0 8.61E+07 5.43E+07 - - - 5.5075 0.9982 221125_WJC_METTL3_EV_vs_WT_F05.15880.15880.3 2.17E-09 Dec-44 K.HSDVLFLAVK[136.11]PH.L "sp|Q96C36|P5CR2_HUMAN,tr|A0A087WX69|A0A087WX69_HUMAN,tr|A0A087WZF0|A0A087WZF0_HUMAN,tr|A0A087WTV6|A0A087WTV6_HUMAN,tr|J3KR12|J3KR12_HUMAN" 5 1369.7598 0.94 67394 15880 3 1369.760442 457.5939 Pyrroline-5-carboxylate reductase 2 OS=Homo sapiens OX=9606 GN=PYCR2 PE=1 SV=1 6.92 2800.2 - 543290 - - - 0.4899 - 2.394 0.567 - 215.5 1 1 0 0.0007 12 0 0 0 4.13E+06 4.37E+06 - - - 7.281 0.9993 221125_WJC_METTL3_EV_vs_WT_F05.15881.15881.3 0.000427 Nov-44 K.IRDYAFVHFTSR.E "sp|A0AV96|RBM47_HUMAN,tr|B7Z8Z7|B7Z8Z7_HUMAN,tr|D6R9D6|D6R9D6_HUMAN" 3 1510.7681 3.5 67395 15881 3 1510.768488 504.5966 RNA-binding protein 47 OS=Homo sapiens OX=9606 GN=RBM47 PE=1 SV=2 8.75 2800.3 - 343445 - - - 0.2588 - 2.112 0.379 - 174.6 1 2 1 0.0004 12 0 0 0 3.68E+06 1.05E+06 - - - 4.8377 0.9999 221125_WJC_METTL3_EV_vs_WT_F05.15882.15882.2 7.10E-06 26-Aug K.LTFDTTFSPNTGKK.S "sp|P45880|VDAC2_HUMAN,tr|Q5JSD1|Q5JSD1_HUMAN,tr|Q5JSD2|Q5JSD2_HUMAN,tr|A0A0A0MR02|A0A0A0MR02_HUMAN" 4 1555.7882 1.12 67396 15882 2 1555.788906 778.9014 Voltage-dependent anion-selective channel protein 2 OS=Homo sapiens OX=9606 GN=VDAC2 PE=1 SV=2 8.59 2800.4 - 253247 - - - 0.439 - 2.012 0.552 - 183.1 1 2 0 0.0007 14 0 0 0 3.68E+06 3.30E+06 - - - 4.8723 1 221125_WJC_METTL3_EV_vs_WT_F05.15886.15886.2 2.50E-09 Dec-32 K.SQVFSTAADGQTQVEIK[136.11].V "sp|P38646|GRP75_HUMAN,tr|A0A7I2V2S7|A0A7I2V2S7_HUMAN,tr|A0A7I2V2G2|A0A7I2V2G2_HUMAN,tr|A0A7I2YQB2|A0A7I2YQB2_HUMAN,tr|D6RCD7|D6RCD7_HUMAN" 5 1815.9094 0.16 67399 15886 2 1815.911274 908.962 "Stress-70 protein, mitochondrial OS=Homo sapiens OX=9606 GN=HSPA9 PE=1 SV=2" 4.37 2801 - 140530 - - - 1.0276 - 2.61 0.656 - 259.9 1 2 0 0.0019 17 0 0 0 3.39E+05 2.07E+06 - - - 6.2442 1 221125_WJC_METTL3_EV_vs_WT_F05.15888.15888.3 5.86E-07 Dec-52 K.LTFDTTFSPNTGK[136.11]K[136.11].S "sp|P45880|VDAC2_HUMAN,tr|Q5JSD1|Q5JSD1_HUMAN,tr|Q5JSD2|Q5JSD2_HUMAN,tr|A0A0A0MR02|A0A0A0MR02_HUMAN" 4 1571.8166 1.2 67400 15888 3 1571.816768 524.9462 Voltage-dependent anion-selective channel protein 2 OS=Homo sapiens OX=9606 GN=VDAC2 PE=1 SV=2 8.59 2801.2 - 5.92E+06 - - - 0.0922 - 2.497 0.593 - 121.6 1 2 0 0.0001 14 0 0 0 8.08E+07 6.72E+07 - - - 7.5832 1 221125_WJC_METTL3_EV_vs_WT_F05.15889.15889.3 2.41E-07 13/60 R.VPMTFITNSNGEVDHR.V sp|Q9Y2X9|ZN281_HUMAN 1 1815.8574 1.23 67401 15889 3 1815.857783 606.2931 Zinc finger protein 281 OS=Homo sapiens OX=9606 GN=ZNF281 PE=1 SV=1 5.32 2801.2 - 2.28E+06 - - - 0.2208 - 2.681 0.552 - 162.3 1 2 0 0.0004 16 0 0 0 3.76E+07 3.05E+07 - - - 7.2246 0.9998 221125_WJC_METTL3_EV_vs_WT_F05.15890.15890.3 0.00038 Nov-68 K.YGQFSGLNPGGRPITPPR.N "sp|P62136|PP1A_HUMAN,tr|A0A7I2V4F7|A0A7I2V4F7_HUMAN,tr|E9PMD7|E9PMD7_HUMAN" 3 1912.9908 1.89 67402 15890 3 1912.992246 638.6709 Serine\threonine-protein phosphatase PP1-alpha catalytic subunit OS=Homo sapiens OX=9606 GN=PPP1CA PE=1 SV=1 10.84 2801.3 - 2.32E+06 - - - 0.7663 - 1.913 0.409 - 123.6 1 2 0 0.0015 18 0 0 0 3.40E+07 1.80E+07 - - - 4.7148 1 221125_WJC_METTL3_EV_vs_WT_F05.15891.15891.3 2.38E-05 14/60 K.FHQFLVSETESGNISR[166.11].Q "sp|Q08J23|NSUN2_HUMAN,tr|A0A140T9Y7|A0A140T9Y7_HUMAN" 2 1859.9041 1.21 67403 15891 3 1859.904299 620.9753 RNA cytosine C(5)-methyltransferase NSUN2 OS=Homo sapiens OX=9606 GN=NSUN2 PE=1 SV=2 5.4 2801.4 - 1.70E+06 - - - 0.0823 - 3.17 0.551 - 306.6 1 2 0 0.0002 16 0 0 0 3.73E+07 3.10E+07 - - - 7.6434 1 221125_WJC_METTL3_EV_vs_WT_F05.15892.15892.3 7.26E-09 16/60 K.FHQFLVSETESGNISR.Q "sp|Q08J23|NSUN2_HUMAN,tr|A0A140T9Y7|A0A140T9Y7_HUMAN" 2 1849.8959 1.21 67404 15892 3 1849.895139 617.6392 RNA cytosine C(5)-methyltransferase NSUN2 OS=Homo sapiens OX=9606 GN=NSUN2 PE=1 SV=2 5.4 2801.4 - 1.41E+06 - - - -0.3984 - 3.242 0.606 - 470.9 1 2 0 -0.0007 16 0 0 0 3.73E+07 3.10E+07 - - - 8.314 1 221125_WJC_METTL3_EV_vs_WT_F05.15893.15893.3 7.48E-06 13/44 R.C[160.03]QSLTEDLEFR[166.11]K[136.11].S "sp|P20700|LMNB1_HUMAN,tr|E9PBF6|E9PBF6_HUMAN,tr|A0A0D9SFE5|A0A0D9SFE5_HUMAN" 3 1542.7467 0.91 67405 15893 3 1542.746838 515.2562 Lamin-B1 OS=Homo sapiens OX=9606 GN=LMNB1 PE=1 SV=2 4.68 2801.5 - 1.16E+06 - - - 0.081 - 2.59 0.475 - 381 1 2 0 0.0001 12 0 0 0 1.04E+07 1.15E+07 - - - 6.4736 0.9952 221125_WJC_METTL3_EV_vs_WT_F05.15895.15895.3 8.15E-06 13/48 K.LQEELDK[136.11]YSQALR[166.11].K "sp|Q15643|TRIPB_HUMAN,tr|H0YJ97|H0YJ97_HUMAN" 2 1609.8431 1.1 67407 15895 3 1609.843858 537.6216 Thyroid receptor-interacting protein 11 OS=Homo sapiens OX=9606 GN=TRIP11 PE=1 SV=3 4.68 2801.7 - 926566 - - - 0.4982 - 2.509 0.201 - 347.1 1 2 1 0.0008 13 0 0 0 9.76E+07 8.90E+07 - - - 3.2748 0.9999 221125_WJC_METTL3_EV_vs_WT_F05.15896.15896.2 1.43E-05 15/28 R.GPSLNPVLDYDHGSR[166.11].S "sp|P43243|MATR3_HUMAN,tr|A8MXP9|A8MXP9_HUMAN,tr|D6R991|D6R991_HUMAN,tr|A0A0R4J2E8|A0A0R4J2E8_HUMAN,tr|D6REM6|D6REM6_HUMAN" 5 1635.7881 1.59 67408 15896 2 1635.788247 818.9013 Matrin-3 OS=Homo sapiens OX=9606 GN=MATR3 PE=1 SV=2 5.21 2801.9 - 891525 - - - 0.118 - 2.795 0.555 - 525.8 1 2 0 0.0002 15 0 0 0 8.61E+07 5.43E+07 - - - 5.6671 1 221125_WJC_METTL3_EV_vs_WT_F05.15897.15897.2 6.40E-07 17/24 K.TGSQYDIQDAIDK.G sp|P15924|DESP_HUMAN 1 1452.6733 10.2 67409 15897 2 1452.675519 727.3439 Desmoplakin OS=Homo sapiens OX=9606 GN=DSP PE=1 SV=3 3.93 2802 - 811203 - - - 1.5599 - 3.144 0.609 - 1186.1 1 2 0 0.0023 13 0 0 0 5.91E+07 5.79E+06 - - - 6.4783 0.9999 221125_WJC_METTL3_EV_vs_WT_F05.15901.15901.4 0.00112 13/78 K.TFIIGELHPDDRPK.L "sp|P00167|CYB5_HUMAN,tr|J3KNC7|J3KNC7_HUMAN" 2 1636.8573 1.49 67413 15901 4 1636.856162 410.2216 Cytochrome b5 OS=Homo sapiens OX=9606 GN=CYB5A PE=1 SV=2 5.35 2802.5 - 501455 - - - -0.6989 - 2.238 0.418 - 114 1 2 0 -0.0011 14 0 0 0 4.68E+07 3.15E+07 - - - 3.1571 1 221125_WJC_METTL3_EV_vs_WT_F05.15902.15902.2 5.31E-08 14/30 K.VDENFDC[160.03]VEADDVEGK[136.11].L sp|O14929|HAT1_HUMAN 1 1847.7611 0.7 67414 15902 2 1847.758697 924.8878 Histone acetyltransferase type B catalytic subunit OS=Homo sapiens OX=9606 GN=HAT1 PE=1 SV=1 3.62 2802.6 - 175335 - - - -1.2945 - 3.213 0.69 - 875.2 1 2 0 -0.0024 16 0 0 0 1.00E+07 1.44E+07 - - - 7.0062 0.9999 221125_WJC_METTL3_EV_vs_WT_F05.15905.15905.3 3.53E-05 15/48 K.LQEELDKYSQALR.K "sp|Q15643|TRIPB_HUMAN,tr|H0YJ97|H0YJ97_HUMAN" 2 1591.8206 1.09 67415 15905 3 1591.820364 531.6141 Thyroid receptor-interacting protein 11 OS=Homo sapiens OX=9606 GN=TRIP11 PE=1 SV=3 4.68 2803 - 2.11E+06 - - - -0.1395 - 2.893 0.47 - 451.1 1 2 1 -0.0002 13 0 0 0 9.60E+07 8.80E+07 - - - 6.6602 1 221125_WJC_METTL3_EV_vs_WT_F05.15908.15908.3 1.74E-06 Nov-64 R.WNSPAEEGSSDC[160.03]EVFSK[136.11].N "sp|P34932|HSP74_HUMAN,tr|A0A087WTS8|A0A087WTS8_HUMAN,tr|A0A087WYC1|A0A087WYC1_HUMAN" 3 1935.8036 0.03 67418 15908 3 1935.804036 646.2752 Heat shock 70 kDa protein 4 OS=Homo sapiens OX=9606 GN=HSPA4 PE=1 SV=4 4 2803.3 - 1.19E+06 - - - 0.2139 - 2.088 0.623 - 128.1 1 2 0 0.0004 17 0 0 0 7.68E+05 2.35E+07 - - - 7.3456 0.9998 221125_WJC_METTL3_EV_vs_WT_F05.15912.15912.3 0.0384 Dec-36 K.K[136.11]SEEEIDFLR[166.11].S "sp|Q9Y262|EIF3L_HUMAN,tr|B0QY89|B0QY89_HUMAN,tr|B0QY90|B0QY90_HUMAN" 3 1282.6524 1.05 67422 15912 3 1282.652424 428.5581 Eukaryotic translation initiation factor 3 subunit L OS=Homo sapiens OX=9606 GN=EIF3L PE=1 SV=1 4.41 2803.7 - 725489 - - - 0.0172 - 1.862 0.368 - 317.3 1 2 0 0 10 0 0 0 1.22E+07 1.17E+07 - - - 4.4583 0.9999 221125_WJC_METTL3_EV_vs_WT_F05.15916.15916.2 1.06E-07 28-Oct R.SFSLASSSNSPISQR[166.11].R sp|Q9BXB4|OSB11_HUMAN 1 1576.7721 0.94 67426 15916 2 1576.77084 789.3933 Oxysterol-binding protein-related protein 11 OS=Homo sapiens OX=9606 GN=OSBPL11 PE=1 SV=2 9.47 2804.2 - 330532 - - - -0.7794 - 2.336 0.526 - 289.3 1 2 0 -0.0012 15 0 0 0 5.11E+06 5.41E+06 - - - 5.0116 1 221125_WJC_METTL3_EV_vs_WT_F05.15917.15917.2 7.38E-08 Nov-32 R.WNSPAEEGSSDC[160.03]EVFSK.N "sp|P34932|HSP74_HUMAN,tr|A0A087WTS8|A0A087WTS8_HUMAN,tr|A0A087WYC1|A0A087WYC1_HUMAN" 3 1927.7894 0.08 67427 15917 2 1927.781045 964.902 Heat shock 70 kDa protein 4 OS=Homo sapiens OX=9606 GN=HSPA4 PE=1 SV=4 4 2804.4 - 320235 - - - -4.3454 - 2.512 0.691 - 328.7 1 2 0 -0.0084 17 0 0 0 5.94E+06 7.42E+07 - - - 6.4066 0.9612 221125_WJC_METTL3_EV_vs_WT_F05.15921.15921.3 0.729 Aug-44 R.K[136.11]NVESFLEAC[160.03]R[166.11]K.M "sp|O75427|LRCH4_HUMAN,tr|A0A087X197|A0A087X197_HUMAN,tr|H7C5D9|H7C5D9_HUMAN" 3 1497.7729 - 67430 15921 3 1497.770884 500.2649 Leucine-rich repeat and calponin homology domain-containing protein 4 OS=Homo sapiens OX=9606 GN=LRCH4 PE=1 SV=2 8.2 2804.8 - 2.90E+06 - - - -1.3246 - 1.403 0.145 - 64.7 1 2 0 -0.002 12 0 0 0 - - - - - 1.0946 0.9982 221125_WJC_METTL3_EV_vs_WT_F05.15923.15923.2 4.42E-05 13/24 R.VGIQQGLLSQSTR.T "sp|Q9BY77|PDIP3_HUMAN,tr|F6VRR5|F6VRR5_HUMAN,tr|F8WCX5|F8WCX5_HUMAN,tr|Q6R954|Q6R954_HUMAN,tr|Q8WUT1|Q8WUT1_HUMAN,tr|F8WEE2|F8WEE2_HUMAN" 6 1385.7627 1.24 67432 15923 2 1385.756392 693.8886 Polymerase delta-interacting protein 3 OS=Homo sapiens OX=9606 GN=POLDIP3 PE=1 SV=2 9.72 2805 - 493146 - - - -4.5354 - 2.221 0.494 - 523.9 1 2 0 -0.0063 13 0 0 0 1.24E+07 9.95E+06 - - - 4.7357 0.9929 221125_WJC_METTL3_EV_vs_WT_F05.15924.15924.2 1.85E-05 24-Dec P.SLNPVLDYDHGSR.S "sp|P43243|MATR3_HUMAN,tr|A8MXP9|A8MXP9_HUMAN,tr|D6R991|D6R991_HUMAN,tr|A0A0R4J2E8|A0A0R4J2E8_HUMAN,tr|D6REM6|D6REM6_HUMAN" 5 1471.7056 1.71 67433 15924 2 1471.703849 736.8601 Matrin-3 OS=Homo sapiens OX=9606 GN=MATR3 PE=1 SV=2 5.19 2805.1 - 384882 - - - -1.1599 - 2.273 0.577 - 478.4 1 1 0 -0.0017 13 0 0 0 4.88E+06 2.86E+06 - - - 5.4096 0.9952 221125_WJC_METTL3_EV_vs_WT_F05.15925.15925.3 0.0296 Nov-48 R.DK[136.11]QLDAAIAWQGK[136.11].L "sp|Q9BUK6|MSTO1_HUMAN,tr|A0A3B3IUD2|A0A3B3IUD2_HUMAN" 2 1458.7802 2.07 67434 15925 3 1458.779024 487.2673 Protein misato homolog 1 OS=Homo sapiens OX=9606 GN=MSTO1 PE=1 SV=1 5.96 2805.2 - 260727 - - - -0.7911 - 1.891 0.27 - 213.9 1 2 1 -0.0012 13 0 0 0 8.94E+06 4.32E+06 - - - 3.2773 0.9999 221125_WJC_METTL3_EV_vs_WT_F05.15928.15928.4 0.0133 19/78 K.TFIIGELHPDDR[166.11]PK[136.11].L "sp|P00167|CYB5_HUMAN,tr|J3KNC7|J3KNC7_HUMAN" 2 1654.8798 1.48 67435 15928 4 1654.876536 414.7272 Cytochrome b5 OS=Homo sapiens OX=9606 GN=CYB5A PE=1 SV=2 5.35 2805.7 - 1.67E+06 - - - -1.9578 - 3.087 0.465 - 309.6 1 2 0 -0.0032 14 0 0 0 4.68E+07 3.15E+07 - - - 3.6827 0.9998 221125_WJC_METTL3_EV_vs_WT_F05.15929.15929.3 3.40E-05 Dec-44 R.NIDVFNVEDQKR.D sp|Q8NBJ4|GOLM1_HUMAN 1 1475.7369 1.36 67436 15929 3 1475.734637 492.9196 Golgi membrane protein 1 OS=Homo sapiens OX=9606 GN=GOLM1 PE=1 SV=1 4.56 2805.7 - 1.59E+06 - - - -1.5037 - 2.649 0.316 - 188.5 1 2 0 -0.0022 12 0 0 0 4.73E+07 3.48E+07 - - - 4.7628 1 221125_WJC_METTL3_EV_vs_WT_F05.15930.15930.3 3.26E-06 15/60 R.VPMTFITNSNGEVDHR[166.11].V sp|Q9Y2X9|ZN281_HUMAN 1 1825.8657 1.27 67437 15930 3 1825.864739 609.6292 Zinc finger protein 281 OS=Homo sapiens OX=9606 GN=ZNF281 PE=1 SV=1 5.32 2805.8 - 2.10E+06 - - - -0.5 - 2.786 0.462 - 193.4 1 2 0 -0.0009 16 0 0 0 3.92E+07 3.09E+07 - - - 6.3196 1 221125_WJC_METTL3_EV_vs_WT_F05.15932.15932.2 2.30E-13 17/32 K.IISNASC[160.03]TTNC[160.03]LAPLAK.V "sp|P04406|G3P_HUMAN,tr|E7EUT5|E7EUT5_HUMAN" 2 1832.9125 1.11 67439 15932 2 1832.910848 917.4635 Glyceraldehyde-3-phosphate dehydrogenase OS=Homo sapiens OX=9606 GN=GAPDH PE=1 SV=3 8.06 2806.1 - 906092 - - - -0.8767 - 3.516 0.747 - 697.2 1 2 0 -0.0016 17 0 0 0 4.55E+07 4.11E+07 - - - 7.649 1 221125_WJC_METTL3_EV_vs_WT_F05.15933.15933.3 4.95E-05 18/52 K.TFIIGELHPDDR[166.11]PK[136.11].L "sp|P00167|CYB5_HUMAN,tr|J3KNC7|J3KNC7_HUMAN" 2 1654.8798 0.2 67440 15933 3 1654.876646 552.6339 Cytochrome b5 OS=Homo sapiens OX=9606 GN=CYB5A PE=1 SV=2 5.35 2806.2 - 838615 - - - -1.8914 - 2.783 0.478 - 359.5 1 2 0 -0.0031 14 0 0 0 3.67E+06 1.81E+07 - - - 6.5884 0.9938 221125_WJC_METTL3_EV_vs_WT_F05.15934.15934.2 1.31E-06 18-Oct N.PVLDYDHGSR.S "sp|P43243|MATR3_HUMAN,tr|A8MXP9|A8MXP9_HUMAN,tr|D6R991|D6R991_HUMAN,tr|A0A0R4J2E8|A0A0R4J2E8_HUMAN,tr|D6REM6|D6REM6_HUMAN" 5 1157.5465 1.78 67441 15934 2 1157.545645 579.7805 Matrin-3 OS=Homo sapiens OX=9606 GN=MATR3 PE=1 SV=2 5.22 2806.3 - 792734 - - - -0.7697 - 1.869 0.619 - 315 1 1 0 -0.0009 10 0 0 0 9.23E+06 5.19E+06 - - - 5.3583 1 221125_WJC_METTL3_EV_vs_WT_F05.15935.15935.2 1.16E-05 14/28 R.SFSLASSSNSPISQR.R sp|Q9BXB4|OSB11_HUMAN 1 1566.7638 0.94 67442 15935 2 1566.760724 784.3892 Oxysterol-binding protein-related protein 11 OS=Homo sapiens OX=9606 GN=OSBPL11 PE=1 SV=2 9.47 2806.4 - 448902 - - - -1.9626 - 2.924 0.629 - 745.5 1 2 0 -0.0031 15 0 0 0 5.11E+06 5.41E+06 - - - 6.3237 1 221125_WJC_METTL3_EV_vs_WT_F05.15936.15936.2 9.04E-08 15/30 R.DANVSGTLVSSSTLEK[136.11].K sp|Q96IZ0|PAWR_HUMAN 1 1614.8192 0.29 67443 15936 2 1614.818293 808.4169 PRKC apoptosis WT1 regulator protein OS=Homo sapiens OX=9606 GN=PAWR PE=1 SV=1 4.37 2806.6 - 361381 - - - -0.5592 - 3.074 0.586 - 640.9 1 2 0 -0.0009 16 0 0 0 1.33E+06 4.60E+06 - - - 6.1298 0.9997 221125_WJC_METTL3_EV_vs_WT_F05.15938.15938.3 2.14E-08 Dec-68 K.IILSNPPSQGDYHGC[160.03]PFR.H "sp|P49643|PRI2_HUMAN,tr|A0A5F9ZHU7|A0A5F9ZHU7_HUMAN" 2 2056.9789 0.43 67444 15938 3 2056.968151 686.6669 DNA primase large subunit OS=Homo sapiens OX=9606 GN=PRIM2 PE=1 SV=2 6.73 2806.8 - 319392 - - - -5.2232 - 2.484 0.587 - 120.1 1 2 0 -0.0107 18 0 0 0 4.59E+06 1.07E+07 - - - 7.3472 0.9989 221125_WJC_METTL3_EV_vs_WT_F05.15944.15944.2 0.0789 15/18 R.R[166.11]VLQALEGLK[136.11].M "sp|P39019|RS19_HUMAN,tr|A0A075B6E2|A0A075B6E2_HUMAN" 2 1143.7095 1.07 67449 15944 2 1143.708262 572.862 40S ribosomal protein S19 OS=Homo sapiens OX=9606 GN=RPS19 PE=1 SV=2 8.75 2807.4 - 1.12E+06 - - - -1.0501 - 2.504 0.122 - 824.7 1 2 0 -0.0012 10 0 0 0 2.87E+07 2.68E+07 - - - 2.5038 0.9976 221125_WJC_METTL3_EV_vs_WT_F05.15945.15945.3 0.000298 13/48 R.DKQLDAAIAWQGK.L "sp|Q9BUK6|MSTO1_HUMAN,tr|A0A3B3IUD2|A0A3B3IUD2_HUMAN" 2 1442.7518 2.04 67450 15945 3 1442.750161 481.9245 Protein misato homolog 1 OS=Homo sapiens OX=9606 GN=MSTO1 PE=1 SV=1 5.96 2807.5 - 671021 - - - -1.1208 - 2.294 0.272 - 282.7 1 2 1 -0.0016 13 0 0 0 8.82E+06 4.32E+06 - - - 3.8233 1 221125_WJC_METTL3_EV_vs_WT_F05.15946.15946.3 6.95E-06 15/60 R.ESALASADLEEEIHQK.Q "sp|P42696|RBM34_HUMAN,tr|Q5TCT4|Q5TCT4_HUMAN,tr|A2A2V2|A2A2V2_HUMAN" 3 1768.8479 1 67451 15946 3 1768.843669 590.6233 RNA-binding protein 34 OS=Homo sapiens OX=9606 GN=RBM34 PE=1 SV=2 4.25 2807.6 - 580560 - - - -2.405 - 3.101 0.53 - 349 1 2 0 -0.0043 16 0 0 0 9.05E+06 9.07E+06 - - - 7.3517 0.9998 221125_WJC_METTL3_EV_vs_WT_F05.15947.15947.3 1.85E-06 15/36 R.R[166.11]VLQALEGLK[136.11].M "sp|P39019|RS19_HUMAN,tr|A0A075B6E2|A0A075B6E2_HUMAN" 2 1143.7095 0.001 67452 15947 3 1143.706812 382.2438 40S ribosomal protein S19 OS=Homo sapiens OX=9606 GN=RPS19 PE=1 SV=2 8.75 2807.8 - 540178 - - - -2.3179 - 2.754 0.357 - 395.1 1 2 0 -0.0027 10 0 0 0 0.00E+00 1.25E+07 - - - 5.478 1 221125_WJC_METTL3_EV_vs_WT_F05.15948.15948.3 3.59E-12 17/68 R.SSLENPEHDESGALVLPR.V sp|Q9BQ50|TREX2_HUMAN 1 1948.949 999 67453 15948 3 1948.94617 650.657 Three prime repair exonuclease 2 OS=Homo sapiens OX=9606 GN=TREX2 PE=1 SV=2 4.4 2807.9 - 525707 - - - -1.4695 - 3.486 0.65 - 546.3 1 2 0 -0.0029 18 0 0 0 8.63E+06 0.00E+00 - - - 8.8956 0.997 221125_WJC_METTL3_EV_vs_WT_F05.15950.15950.2 0.000423 13/24 K.LQEELDK[136.11]YSQALR[166.11].K "sp|Q15643|TRIPB_HUMAN,tr|H0YJ97|H0YJ97_HUMAN" 2 1609.8431 0.98 67455 15950 2 1609.839235 805.9288 Thyroid receptor-interacting protein 11 OS=Homo sapiens OX=9606 GN=TRIP11 PE=1 SV=3 4.68 2808.2 - 441833 - - - -2.3735 - 2.822 0.494 - 637.8 1 2 1 -0.0038 13 0 0 0 5.32E+06 5.43E+06 - - - 5.3511 0.9998 221125_WJC_METTL3_EV_vs_WT_F05.15955.15955.3 0.00148 Nov-36 R.LVNHFVEEFK[136.11].R "sp|P0DMV8|HS71A_HUMAN,sp|P0DMV9|HS71B_HUMAN,tr|V9GZ37|V9GZ37_HUMAN,tr|A0A0G2JIW1|A0A0G2JIW1_HUMAN" 4 1268.6645 0.07 67458 15955 3 1268.661653 423.8954 Heat shock 70 kDa protein 1A OS=Homo sapiens OX=9606 GN=HSPA1A PE=1 SV=1 5.4 2808.8 - 3.02E+06 - - - -2.2228 - 2.229 0.385 - 211.7 1 2 0 -0.0028 10 0 0 0 3.73E+06 5.48E+07 - - - 5.1725 1 221125_WJC_METTL3_EV_vs_WT_F05.15956.15956.2 1.67E-09 17/32 K.IISNASC[160.03]TTNC[160.03]LAPLAK[136.11].V "sp|P04406|G3P_HUMAN,tr|E7EUT5|E7EUT5_HUMAN" 2 1840.9267 1.11 67459 15956 2 1840.923036 921.4706 Glyceraldehyde-3-phosphate dehydrogenase OS=Homo sapiens OX=9606 GN=GAPDH PE=1 SV=3 8.06 2808.9 - 2.18E+06 - - - -1.9659 - 3.447 0.673 - 633.8 1 2 0 -0.0036 17 0 0 0 4.55E+07 4.11E+07 - - - 7.0531 0.9998 221125_WJC_METTL3_EV_vs_WT_F05.15958.15958.3 0.000128 15/48 R.QR[166.11]YEILTPNSIPK[136.11].G sp|P35579|MYH9_HUMAN 1 1575.874 0.93 67461 15958 3 1575.874677 526.2986 Myosin-9 OS=Homo sapiens OX=9606 GN=MYH9 PE=1 SV=4 8.59 2809 - 1.98E+06 - - - 0.4537 - 2.483 0.443 - 405.3 1 2 1 0.0007 13 0 0 0 6.48E+07 6.97E+07 - - - 5.9446 0.999 221125_WJC_METTL3_EV_vs_WT_F05.15960.15960.3 5.70E-06 15/48 R.QRYEILTPNSIPK.G sp|P35579|MYH9_HUMAN 1 1557.8515 0.93 67463 15960 3 1557.851641 520.2911 Myosin-9 OS=Homo sapiens OX=9606 GN=MYH9 PE=1 SV=4 8.59 2809.2 - 1.36E+06 - - - 0.0956 - 2.525 0.308 - 396 1 2 1 0.0001 13 0 0 0 6.48E+07 6.98E+07 - - - 4.4852 0.9999 221125_WJC_METTL3_EV_vs_WT_F05.15963.15963.2 5.26E-07 Nov-38 R.SAPAGASEPPPPGGVGLGIR.T "sp|Q8IWZ3|ANKH1_HUMAN,tr|E9PDP5|E9PDP5_HUMAN,tr|D6RHC4|D6RHC4_HUMAN" 3 1785.9373 2.02 67466 15963 2 1785.937347 893.9759 Ankyrin repeat and KH domain-containing protein 1 OS=Homo sapiens OX=9606 GN=ANKHD1 PE=1 SV=1 5.72 2809.6 - 468666 - - - 0 - 2.144 0.595 - 126.7 1 2 0 0 20 0 0 0 1.31E+07 6.50E+06 - - - 5.3107 1 221125_WJC_METTL3_EV_vs_WT_F05.15969.15969.3 7.61E-08 15/60 R.AFDQDGDGHITVDELR.R sp|Q9NZT1|CALL5_HUMAN 1 1786.8122 999 67470 15969 3 1786.809884 596.6113 Calmodulin-like protein 5 OS=Homo sapiens OX=9606 GN=CALML5 PE=1 SV=2 4.03 2810.3 - 1.69E+06 - - - -1.2995 - 2.965 0.647 - 270.7 1 2 0 -0.0023 16 0 0 0 2.93E+07 0.00E+00 - - - 8.5415 0.9993 221125_WJC_METTL3_EV_vs_WT_F05.15973.15973.2 0.000537 30-Nov K.AQQATPGGAAPTIFSR.L sp|Q9BX68|HINT2_HUMAN 1 1571.8056 2.21 67474 15973 2 1571.800655 786.9101 Adenosine 5'-monophosphoramidase HINT2 OS=Homo sapiens OX=9606 GN=HINT2 PE=1 SV=1 9.79 2810.8 - 308928 - - - -3.1492 - 2.376 0.48 - 205.8 1 2 0 -0.0049 16 0 0 0 6.67E+06 3.01E+06 - - - 4.7124 0.9998 221125_WJC_METTL3_EV_vs_WT_F05.15974.15974.2 2.09E-06 Sep-38 R.SAPAGASEPPPPGGVGLGIR[166.11].T "sp|Q8IWZ3|ANKH1_HUMAN,tr|E9PDP5|E9PDP5_HUMAN,tr|D6RHC4|D6RHC4_HUMAN" 3 1795.9456 2.02 67475 15974 2 1795.944122 898.9801 Ankyrin repeat and KH domain-containing protein 1 OS=Homo sapiens OX=9606 GN=ANKHD1 PE=1 SV=1 5.72 2810.9 - 230239 - - - -0.8324 - 2 0.482 - 62.1 1 2 0 -0.0015 20 0 0 0 1.31E+07 6.50E+06 - - - 4.3047 0.9998 221125_WJC_METTL3_EV_vs_WT_F05.15975.15975.3 0.000103 Aug-48 R.ANPQVGVAFPHIK[136.11].H sp|P13010|XRCC5_HUMAN 1 1384.7707 1.45 67476 15975 3 1384.772294 462.5975 X-ray repair cross-complementing protein 5 OS=Homo sapiens OX=9606 GN=XRCC5 PE=1 SV=3 8.8 2811.1 - 230142 - - - 1.1728 - 1.634 0.426 - 67.7 1 2 0 0.0016 13 0 0 0 1.06E+07 7.31E+06 - - - 4.6204 0.9995 221125_WJC_METTL3_EV_vs_WT_F05.15980.15980.3 0.00142 13/52 K.NVKDPVEIQTLVNK.A "sp|Q9HD34|LYRM4_HUMAN,tr|F5H189|F5H189_HUMAN,tr|C9JRX8|C9JRX8_HUMAN,tr|C9JY28|C9JY28_HUMAN,tr|H7C4Q5|H7C4Q5_HUMAN" 5 1595.8883 1.22 67479 15980 3 1595.891984 532.97 LYR motif-containing protein 4 OS=Homo sapiens OX=9606 GN=LYRM4 PE=1 SV=1 6.07 2811.7 - 1.13E+06 - - - 2.326 - 2.868 0.424 - 257.9 1 2 1 0.0037 14 0 0 0 1.56E+07 1.28E+07 - - - 6.0662 0.9995 221125_WJC_METTL3_EV_vs_WT_F05.15981.15981.2 0.000418 24-Nov K.DAQPSFSAEDIAK[136.11].L "sp|P25205|MCM3_HUMAN,tr|J3KQ69|J3KQ69_HUMAN,tr|A0A499FHX9|A0A499FHX9_HUMAN" 3 1385.6554 0.54 67480 15981 2 1385.652608 693.835 DNA replication licensing factor MCM3 OS=Homo sapiens OX=9606 GN=MCM3 PE=1 SV=3 4.03 2811.8 - 959478 - - - -2.033 - 1.913 0.435 - 294.6 1 2 0 -0.0028 13 0 0 0 1.07E+07 1.98E+07 - - - 3.9179 1 221125_WJC_METTL3_EV_vs_WT_F05.15983.15983.3 1.83E-13 20/96 K.LVQDVANNTNEEAGDGTTTATVLAR[166.11].S "sp|P10809|CH60_HUMAN,tr|C9JL25|C9JL25_HUMAN,tr|A0A7I2V2X6|A0A7I2V2X6_HUMAN,tr|A0A7I2YQK6|A0A7I2YQK6_HUMAN,tr|A0A7I2V599|A0A7I2V599_HUMAN,tr|E7EXB4|E7EXB4_HUMAN,tr|A0A7I2YQ71|A0A7I2YQ71_HUMAN,tr|E7ESH4|E7ESH4_HUMAN,tr|A0A7I2V5M1|A0A7I2V5M1_HUMAN,tr|A0A7I2V5K3|A0A7I2V5K3_HUMAN,tr|A0A7I2V369|A0A7I2V369_HUMAN" 11 2569.2495 1.66 67482 15983 3 2570.234174 857.4238 "60 kDa heat shock protein, mitochondrial OS=Homo sapiens OX=9606 GN=HSPD1 PE=1 SV=2" 3.92 2812 - 422170 - - - 383.2446 - 3.583 0.7 - 572.3 1 2 0 0.9847 25 0 0 0 2.09E+06 1.26E+06 - - - 9.0076 0.9999 221125_WJC_METTL3_EV_vs_WT_F05.15987.15987.2 2.13E-05 30-Dec R.VADLTEQYNEQYGAVR[166.11].T sp|Q9BWF3|RBM4_HUMAN 1 1864.8831 1.59 67484 15987 2 1864.880388 933.4488 RNA-binding protein 4 OS=Homo sapiens OX=9606 GN=RBM4 PE=1 SV=1 4.14 2812.6 - 363156 - - - -1.4419 - 2.558 0.573 - 233.2 1 2 0 -0.0027 16 0 0 0 1.39E+07 8.77E+06 - - - 5.5815 1 221125_WJC_METTL3_EV_vs_WT_F05.15989.15989.4 3.60E-07 19/102 R.VALVTFNSAAHNK[136.11]PSLIR[166.11].D "sp|Q86VP6|CAND1_HUMAN,tr|A0A0C4DGH5|A0A0C4DGH5_HUMAN" 2 1955.1072 0.76 67486 15989 4 1955.103363 489.7841 Cullin-associated NEDD8-dissociated protein 1 OS=Homo sapiens OX=9606 GN=CAND1 PE=1 SV=2 11 2812.7 - 810998 - - - -1.937 - 3.982 0.549 - 388.1 1 2 0 -0.0038 18 0 0 0 5.20E+06 6.82E+06 - - - 4.4768 0.9645 221125_WJC_METTL3_EV_vs_WT_F05.15992.15992.3 2.57E-05 13/60 K.AHEGEIEDLALGPDGK[136.11].L "sp|Q9HCU5|PREB_HUMAN,tr|B5MC98|B5MC98_HUMAN" 2 1657.8039 1.11 67489 15992 3 1658.798425 553.6086 Prolactin regulatory element-binding protein OS=Homo sapiens OX=9606 GN=PREB PE=1 SV=2 4.17 2813.1 - 438063 - - - 599.9172 - 2.347 0.466 - 154.7 1 2 0 0.9945 16 0 0 0 6.32E+06 5.68E+06 - - - 5.649 1 221125_WJC_METTL3_EV_vs_WT_F05.15993.15993.2 3.55E-11 20/30 R.VADLTEQYNEQYGAVR.T sp|Q9BWF3|RBM4_HUMAN 1 1854.8748 1.59 67490 15993 2 1854.877712 928.4447 RNA-binding protein 4 OS=Homo sapiens OX=9606 GN=RBM4 PE=1 SV=1 4.14 2813.3 - 319785 - - - 1.5661 - 3.649 0.716 - 1345.1 1 2 0 0.0029 16 0 0 0 1.39E+07 8.77E+06 - - - 7.5109 1 221125_WJC_METTL3_EV_vs_WT_F05.15994.15994.2 1.78E-08 20/38 H.TPSQELALTQSVGGDSSADR[166.11].L "sp|Q86U44|MTA70_HUMAN,tr|H0YFV6|H0YFV6_HUMAN" 2 2027.9635 0.001 67491 15994 2 2027.950797 1014.989 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 4.03 2813.4 - 296820 - - - -6.2698 - 4.048 0.654 - 1224.1 1 1 0 -0.0127 20 0 0 0 0.00E+00 1.34E+07 - - - 7.305 0.9994 221125_WJC_METTL3_EV_vs_WT_F05.15998.15998.3 0.000245 13/64 K.NSAADLEHPEPSLPLSR[166.11].T sp|Q96T58|MINT_HUMAN 1 1841.9147 1.03 67493 15998 3 1841.920505 614.9788 Msx2-interacting protein OS=Homo sapiens OX=9606 GN=SPEN PE=1 SV=1 4.65 2813.9 - 2.07E+06 - - - 3.1456 - 1.952 0.414 - 158.7 1 2 0 0.0058 17 0 0 0 4.62E+07 4.47E+07 - - - 4.8438 1 221125_WJC_METTL3_EV_vs_WT_F05.15999.15999.3 2.27E-13 18/96 K.LVQDVANNTNEEAGDGTTTATVLAR.S "sp|P10809|CH60_HUMAN,tr|C9JL25|C9JL25_HUMAN,tr|A0A7I2V2X6|A0A7I2V2X6_HUMAN,tr|A0A7I2YQK6|A0A7I2YQK6_HUMAN,tr|A0A7I2V599|A0A7I2V599_HUMAN,tr|E7EXB4|E7EXB4_HUMAN,tr|A0A7I2YQ71|A0A7I2YQ71_HUMAN,tr|E7ESH4|E7ESH4_HUMAN,tr|A0A7I2V5M1|A0A7I2V5M1_HUMAN,tr|A0A7I2V5K3|A0A7I2V5K3_HUMAN,tr|A0A7I2V369|A0A7I2V369_HUMAN" 11 2559.2413 -1 67494 15999 3 2560.224927 854.0877 "60 kDa heat shock protein, mitochondrial OS=Homo sapiens OX=9606 GN=HSPD1 PE=1 SV=2" 3.92 2814 - 1.29E+06 - - - 384.3616 - 3.727 0.672 - 413.6 1 2 0 0.9837 25 0 0 0 0.00E+00 0.00E+00 - - - 8.7864 1 221125_WJC_METTL3_EV_vs_WT_F05.16001.16001.3 1.58E-06 13/44 R.VHVQFFDDSPTR[166.11].G "sp|P52701|MSH6_HUMAN,tr|A0A494C0M1|A0A494C0M1_HUMAN,tr|C9J7Y7|C9J7Y7_HUMAN,tr|C9JH55|C9JH55_HUMAN,tr|F8WAX8|F8WAX8_HUMAN,tr|C9J8Y8|C9J8Y8_HUMAN,tr|A0A087WWJ1|A0A087WWJ1_HUMAN" 7 1456.6974 0.44 67496 16001 3 1456.695838 486.5731 DNA mismatch repair protein Msh6 OS=Homo sapiens OX=9606 GN=MSH6 PE=1 SV=2 5.21 2814.2 - 733910 - - - -1.1052 - 2.599 0.482 - 211.1 1 2 0 -0.0016 12 0 0 0 5.99E+06 1.35E+07 - - - 6.5608 1 221125_WJC_METTL3_EV_vs_WT_F05.16004.16004.2 2.17E-12 16/30 K.SAVDYNTC[160.03]AGVWSQDK[136.11].W sp|Q9Y5A9|YTHD2_HUMAN 1 1807.7927 1.34 67499 16004 2 1807.791203 904.9036 YTH domain-containing family protein 2 OS=Homo sapiens OX=9606 GN=YTHDF2 PE=1 SV=2 4.21 2814.6 - 539604 - - - -0.8082 - 3.268 0.73 - 1010.1 1 2 0 -0.0015 16 0 0 0 8.48E+07 6.33E+07 - - - 7.3437 1 221125_WJC_METTL3_EV_vs_WT_F05.16010.16010.3 0.0175 Nov-68 R.EDAPIGPHLQSMPSEQIR.N sp|Q14152|EIF3A_HUMAN 1 2003.9735 1.32 67503 16010 3 2003.972684 668.9984 Eukaryotic translation initiation factor 3 subunit A OS=Homo sapiens OX=9606 GN=EIF3A PE=1 SV=1 4.65 2815.3 - 1.53E+06 - - - -0.3947 - 2.701 0.5 - 102.5 1 2 0 -0.0008 18 0 0 0 4.68E+07 3.55E+07 - - - 6.5885 1 221125_WJC_METTL3_EV_vs_WT_F05.16011.16011.2 1.19E-11 17/30 K.SAVDYNTC[160.03]AGVWSQDK.W sp|Q9Y5A9|YTHD2_HUMAN 1 1799.7785 1.34 67504 16011 2 1799.777236 900.8965 YTH domain-containing family protein 2 OS=Homo sapiens OX=9606 GN=YTHDF2 PE=1 SV=2 4.21 2815.3 - 1.87E+06 - - - -0.6823 - 3.441 0.743 - 1135.5 1 2 0 -0.0012 16 0 0 0 8.48E+07 6.33E+07 - - - 7.5666 1 221125_WJC_METTL3_EV_vs_WT_F05.16012.16012.3 6.68E-11 19/68 R.EDAPIGPHLQSMPSEQIR[166.11].N sp|Q14152|EIF3A_HUMAN 1 2013.9817 1.32 67505 16012 3 2013.979881 672.3345 Eukaryotic translation initiation factor 3 subunit A OS=Homo sapiens OX=9606 GN=EIF3A PE=1 SV=1 4.65 2815.4 - 1.50E+06 - - - -0.9255 - 3.484 0.616 - 444.4 1 2 0 -0.0019 18 0 0 0 4.68E+07 3.55E+07 - - - 8.5154 1 221125_WJC_METTL3_EV_vs_WT_F05.16013.16013.2 3.65E-08 15/28 K.TSFEDGSGEC[160.03]EVFC[160.03]K[136.11].N "sp|O95757|HS74L_HUMAN,tr|D6RJ96|D6RJ96_HUMAN,tr|E9PDE8|E9PDE8_HUMAN" 3 1758.6957 0.11 67506 16013 2 1758.694489 880.3551 Heat shock 70 kDa protein 4L OS=Homo sapiens OX=9606 GN=HSPA4L PE=1 SV=3 4 2815.5 - 1.35E+06 - - - -0.6613 - 3.071 0.674 - 784.9 1 2 0 -0.0012 15 0 0 0 5.09E+06 4.50E+07 - - - 6.7773 0.9996 221125_WJC_METTL3_EV_vs_WT_F05.16016.16016.4 1.56E-05 18/84 R.YLYTLVITDKEKAEK.L "sp|P63173|RL38_HUMAN,tr|J3KT73|J3KT73_HUMAN,tr|J3QL01|J3QL01_HUMAN" 3 1812.9873 9.45 67509 16016 4 1812.987186 454.2541 60S ribosomal protein L38 OS=Homo sapiens OX=9606 GN=RPL38 PE=1 SV=2 6.18 2815.9 - 866097 - - - -0.0723 - 3.007 0.407 - 244.5 1 2 2 -0.0001 15 0 0 0 1.48E+08 1.56E+07 - - - 3.1624 1 221125_WJC_METTL3_EV_vs_WT_F05.16018.16018.2 1.60E-05 16/32 K.SQIDVALSQDSTYQGER[166.11].A sp|Q92900|RENT1_HUMAN 1 1905.8944 0.78 67511 16018 2 1905.89633 953.9545 Regulator of nonsense transcripts 1 OS=Homo sapiens OX=9606 GN=UPF1 PE=1 SV=2 4.03 2816.1 - 512735 - - - 1.0284 - 3.365 0.629 - 707.8 1 2 0 0.002 17 0 0 0 4.35E+06 5.58E+06 - - - 6.6694 0.9999 221125_WJC_METTL3_EV_vs_WT_F05.16020.16020.3 6.36E-05 Nov-60 K.WESPAQNTAHLDQFER[166.11].L "sp|P17612|KAPCA_HUMAN,tr|Q15136|Q15136_HUMAN" 2 1937.8896 0.82 67513 16020 3 1937.885752 646.9705 cAMP-dependent protein kinase catalytic subunit alpha OS=Homo sapiens OX=9606 GN=PRKACA PE=1 SV=2 4.65 2816.4 - 268379 - - - -1.9645 - 2.107 0.453 - 134.8 1 2 0 -0.0038 16 0 0 0 2.30E+06 2.79E+06 - - - 5.5017 0.9999 221125_WJC_METTL3_EV_vs_WT_F05.16023.16023.4 4.18E-07 19/84 R.YLYTLVITDK[136.11]EK[136.11]AEK[136.11].L "sp|P63173|RL38_HUMAN,tr|J3KT73|J3KT73_HUMAN,tr|J3QL01|J3QL01_HUMAN" 3 1837.0299 14.99 67515 16023 4 1837.025951 460.2648 60S ribosomal protein L38 OS=Homo sapiens OX=9606 GN=RPL38 PE=1 SV=2 6.18 2816.7 - 1.35E+06 - - - -2.1589 - 3.54 0.574 - 276.2 1 2 2 -0.004 15 0 0 0 2.87E+08 1.91E+07 - - - 4.6733 0.9984 221125_WJC_METTL3_EV_vs_WT_F05.16025.16025.3 0.000352 Dec-44 K.NKLEGLEDALQK.A "sp|P48668|K2C6C_HUMAN,sp|P04259|K2C6B_HUMAN,sp|P02538|K2C6A_HUMAN" 3 1356.7249 999 67516 16025 3 1356.723368 453.2489 "Keratin, type II cytoskeletal 6C OS=Homo sapiens OX=9606 GN=KRT6C PE=1 SV=3" 4.68 2817 - 6.10E+06 - - - -1.1255 - 2.345 0.29 - 359.7 1 2 1 -0.0015 12 0 0 0 5.03E+09 0.00E+00 - - - 4.1352 1 221125_WJC_METTL3_EV_vs_WT_F05.16028.16028.4 2.61E-08 19/84 K.AADHLKPFLDDSTLR.F sp|O43395|PRPF3_HUMAN 1 1697.8737 2.5 67519 16028 4 1697.872189 425.4757 U4\U6 small nuclear ribonucleoprotein Prp3 OS=Homo sapiens OX=9606 GN=PRPF3 PE=1 SV=2 5.3 2817.2 - 1.20E+06 - - - -0.8805 - 3.551 0.53 - 325.3 1 2 0 -0.0015 15 0 0 0 5.72E+07 2.29E+07 - - - 4.2921 1 221125_WJC_METTL3_EV_vs_WT_F05.16029.16029.3 1.26E-08 15/64 K.SQIDVALSQDSTYQGER[166.11].A sp|Q92900|RENT1_HUMAN 1 1905.8944 4.7 67520 16029 3 1905.89364 636.3054 Regulator of nonsense transcripts 1 OS=Homo sapiens OX=9606 GN=UPF1 PE=1 SV=2 4.03 2817.4 - 838665 - - - -0.383 - 3.081 0.605 - 313.2 1 2 0 -0.0007 17 0 0 0 3.90E+07 8.30E+06 - - - 8.1277 0.9999 221125_WJC_METTL3_EV_vs_WT_F05.16032.16032.3 0.000187 Dec-36 K.NSTFSEIFKK.E "sp|P29401|TKT_HUMAN,tr|A0A0B4J1R6|A0A0B4J1R6_HUMAN" 2 1199.6186 1.12 67523 16032 3 1199.617332 400.8802 Transketolase OS=Homo sapiens OX=9606 GN=TKT PE=1 SV=3 8.59 2817.7 - 580235 - - - -1.0895 - 2.185 0.432 - 210.5 1 2 0 -0.0013 10 0 0 0 1.07E+07 9.52E+06 - - - 5.6387 0.9997 221125_WJC_METTL3_EV_vs_WT_F05.16034.16034.4 0.00153 14/84 K.AADHLK[136.11]PFLDDSTLR[166.11].F sp|O43395|PRPF3_HUMAN 1 1715.8962 2.51 67525 16034 4 1715.898357 429.9813 U4\U6 small nuclear ribonucleoprotein Prp3 OS=Homo sapiens OX=9606 GN=PRPF3 PE=1 SV=2 5.3 2818 - 488548 - - - 1.2839 - 2.314 0.361 - 161.1 1 2 0 0.0022 15 0 0 0 5.73E+07 2.29E+07 - - - 2.6677 1 221125_WJC_METTL3_EV_vs_WT_F05.16042.16042.3 1.18E-08 16/56 K.AADHLKPFLDDSTLR.F sp|O43395|PRPF3_HUMAN 1 1697.8737 2.29 67531 16042 3 1697.873413 566.9652 U4\U6 small nuclear ribonucleoprotein Prp3 OS=Homo sapiens OX=9606 GN=PRPF3 PE=1 SV=2 5.3 2818.9 - 2.45E+06 - - - -0.1596 - 3.108 0.631 - 426.8 1 2 0 -0.0003 15 0 0 0 7.41E+07 3.23E+07 - - - 8.5339 1 221125_WJC_METTL3_EV_vs_WT_F05.16043.16043.3 1.92E-07 Dec-60 K.SAVDYNTC[160.03]AGVWSQDK[136.11].W sp|Q9Y5A9|YTHD2_HUMAN 1 1807.7927 1.25 67532 16043 3 1807.790484 603.6048 YTH domain-containing family protein 2 OS=Homo sapiens OX=9606 GN=YTHDF2 PE=1 SV=2 4.21 2819 - 1.73E+06 - - - -1.2059 - 2.644 0.568 - 254.2 1 2 0 -0.0022 16 0 0 0 2.50E+07 2.00E+07 - - - 7.3668 0.9976 221125_WJC_METTL3_EV_vs_WT_F05.16044.16044.3 5.50E-09 16/56 F.R[166.11]VPTANVSVVDLTC[160.03]R[166.11].L "sp|P04406|G3P_HUMAN,tr|E7EUT5|E7EUT5_HUMAN" 2 1705.9048 0.96 67533 16044 3 1705.905214 569.6422 Glyceraldehyde-3-phosphate dehydrogenase OS=Homo sapiens OX=9606 GN=GAPDH PE=1 SV=3 8.25 2819.1 - 1.45E+06 - - - 0.2257 - 3.317 0.468 - 471.6 1 1 0 0.0004 15 0 0 0 8.62E+07 8.99E+07 - - - 6.8864 0.9979 221125_WJC_METTL3_EV_vs_WT_F05.16045.16045.3 0.000326 17/64 Q.KTVEGAGSIAAATGFVK.K "sp|P37840|SYUA_HUMAN,tr|A0A669KB41|A0A669KB41_HUMAN,tr|A0A669KBH5|A0A669KBH5_HUMAN,tr|H6UYS7|H6UYS7_HUMAN,tr|E7EPV7|E7EPV7_HUMAN" 5 1605.8726 1.47 67534 16045 3 1605.871901 536.2982 Alpha-synuclein OS=Homo sapiens OX=9606 GN=SNCA PE=1 SV=1 8.59 2819.1 - 1.06E+06 - - - -0.449 - 3.136 0.504 - 446.3 1 1 0 -0.0007 17 0 0 0 3.41E+08 2.32E+08 - - - 7.0463 1 221125_WJC_METTL3_EV_vs_WT_F05.16046.16046.2 3.00E-05 15/26 K.AEAGAGSATEFQFR.G "sp|Q9NQ39|RS10L_HUMAN,sp|P46783|RS10_HUMAN" 2 1440.6634 1.52 67535 16046 2 1440.660806 721.339 Putative 40S ribosomal protein S10-like OS=Homo sapiens OX=9606 GN=RPS10P5 PE=5 SV=1 4.53 2819.3 - 1.02E+06 - - - -1.7707 - 3.185 0.552 - 869.8 1 2 0 -0.0026 14 0 0 0 3.91E+07 2.58E+07 - - - 6.0243 1 221125_WJC_METTL3_EV_vs_WT_F05.16048.16048.2 0.000134 13/26 K.AEAGAGSATEFQFR[166.11].G "sp|Q9NQ39|RS10L_HUMAN,sp|P46783|RS10_HUMAN" 2 1450.6716 1.58 67537 16048 2 1450.666382 726.3431 Putative 40S ribosomal protein S10-like OS=Homo sapiens OX=9606 GN=RPS10P5 PE=5 SV=1 4.53 2819.5 - 745096 - - - -3.6156 - 3.129 0.538 - 598.5 1 2 0 -0.0052 14 0 0 0 3.73E+07 2.36E+07 - - - 5.8756 1 221125_WJC_METTL3_EV_vs_WT_F05.16049.16049.2 4.94E-08 13/28 K.TSFEDGSGEC[160.03]EVFC[160.03]K.N "sp|O95757|HS74L_HUMAN,tr|D6RJ96|D6RJ96_HUMAN,tr|E9PDE8|E9PDE8_HUMAN" 3 1750.6815 0.11 67538 16049 2 1750.681432 876.348 Heat shock 70 kDa protein 4L OS=Homo sapiens OX=9606 GN=HSPA4L PE=1 SV=3 4 2819.7 - 480952 - - - -0.0114 - 2.745 0.706 - 659 1 2 0 0 15 0 0 0 5.09E+06 4.50E+07 - - - 6.7381 1 221125_WJC_METTL3_EV_vs_WT_F05.16050.16050.2 5.55E-05 15/32 K.SQIDVALSQDSTYQGER.A sp|Q92900|RENT1_HUMAN 1 1895.8861 0.78 67539 16050 2 1895.883109 948.9503 Regulator of nonsense transcripts 1 OS=Homo sapiens OX=9606 GN=UPF1 PE=1 SV=2 4.03 2819.8 - 443768 - - - -1.5776 - 3.053 0.602 - 579.2 1 2 0 -0.003 17 0 0 0 4.35E+06 5.58E+06 - - - 6.2305 0.9985 221125_WJC_METTL3_EV_vs_WT_F05.16056.16056.3 3.86E-11 17/56 F.RVPTANVSVVDLTC[160.03]R.L "sp|P04406|G3P_HUMAN,tr|E7EUT5|E7EUT5_HUMAN" 2 1685.8883 0.98 67543 16056 3 1685.887954 562.97 Glyceraldehyde-3-phosphate dehydrogenase OS=Homo sapiens OX=9606 GN=GAPDH PE=1 SV=3 8.25 2820.6 - 2.61E+06 - - - -0.1987 - 3.329 0.526 - 545.3 1 1 0 -0.0003 15 0 0 0 8.61E+07 8.83E+07 - - - 7.5425 0.9994 221125_WJC_METTL3_EV_vs_WT_F05.16057.16057.3 5.12E-06 13/48 K.TKEVYELLDSPGK.V "sp|P22234|PUR6_HUMAN,tr|E9PBS1|E9PBS1_HUMAN" 2 1477.7664 0.68 67544 16057 3 1477.76967 493.5961 Multifunctional protein ADE2 OS=Homo sapiens OX=9606 GN=PAICS PE=1 SV=3 4.68 2820.7 - 1.06E+06 - - - 2.1959 - 2.358 0.43 - 308.5 1 2 1 0.0032 13 0 0 0 5.70E+07 8.38E+07 - - - 5.659 1 221125_WJC_METTL3_EV_vs_WT_F05.16059.16059.3 6.94E-07 13/36 K.NSTFSEIFK[136.11]K[136.11].E "sp|P29401|TKT_HUMAN,tr|A0A0B4J1R6|A0A0B4J1R6_HUMAN" 2 1215.647 1.12 67546 16059 3 1215.646099 406.223 Transketolase OS=Homo sapiens OX=9606 GN=TKT PE=1 SV=3 8.59 2820.9 - 894825 - - - -0.7733 - 2.279 0.53 - 263.4 1 2 0 -0.0009 10 0 0 0 1.07E+07 9.52E+06 - - - 6.8544 1 221125_WJC_METTL3_EV_vs_WT_F05.16063.16063.2 0.000137 14/24 K.TKEVYELLDSPGK.V "sp|P22234|PUR6_HUMAN,tr|E9PBS1|E9PBS1_HUMAN" 2 1477.7664 1.06 67550 16063 2 1477.767584 739.8905 Multifunctional protein ADE2 OS=Homo sapiens OX=9606 GN=PAICS PE=1 SV=3 4.68 2821.4 - 185377 - - - 0.7843 - 2.748 0.601 - 568.9 1 2 1 0.0012 13 0 0 0 1.40E+07 1.32E+07 - - - 6.0741 1 221125_WJC_METTL3_EV_vs_WT_F05.16067.16067.3 1.09E-07 14/60 K.SAVDYNTC[160.03]AGVWSQDK.W sp|Q9Y5A9|YTHD2_HUMAN 1 1799.7785 1.24 67552 16067 3 1799.777104 600.9334 YTH domain-containing family protein 2 OS=Homo sapiens OX=9606 GN=YTHDF2 PE=1 SV=2 4.21 2821.9 - 1.81E+06 - - - -0.7556 - 2.666 0.582 - 308.6 1 2 0 -0.0014 16 0 0 0 2.50E+07 2.02E+07 - - - 7.5444 0.9987 221125_WJC_METTL3_EV_vs_WT_F05.16069.16069.3 4.52E-08 20/52 M.TFTTFDLGGHEQAR.R "sp|Q9NR31|SAR1A_HUMAN,tr|Q5SQT8|Q5SQT8_HUMAN" 2 1578.7427 1.06 67554 16069 3 1578.740251 527.2548 GTP-binding protein SAR1a OS=Homo sapiens OX=9606 GN=SAR1A PE=1 SV=1 5.29 2822 - 961068 - - - -1.5322 - 3.242 0.605 - 505 1 1 0 -0.0024 14 0 0 0 4.31E+07 4.06E+07 - - - 8.4102 1 221125_WJC_METTL3_EV_vs_WT_F05.16070.16070.3 8.23E-07 Dec-60 R.K[136.11]FNALFAQGNYSEAAK[136.11].V "sp|Q00610|CLH1_HUMAN,tr|A0A087WVQ6|A0A087WVQ6_HUMAN" 2 1773.9021 1.05 67555 16070 3 1773.902121 592.308 Clathrin heavy chain 1 OS=Homo sapiens OX=9606 GN=CLTC PE=1 SV=5 8.5 2822.1 - 752226 - - - 0.0209 - 2.652 0.552 - 261.7 1 2 0 0 16 0 0 0 6.49E+07 6.17E+07 - - - 7.1968 0.9999 221125_WJC_METTL3_EV_vs_WT_F05.16072.16072.3 1.70E-05 Dec-60 R.KFNALFAQGNYSEAAK.V "sp|Q00610|CLH1_HUMAN,tr|A0A087WVQ6|A0A087WVQ6_HUMAN" 2 1757.8737 1.05 67557 16072 3 1757.875539 586.9652 Clathrin heavy chain 1 OS=Homo sapiens OX=9606 GN=CLTC PE=1 SV=5 8.5 2822.4 - 438073 - - - 1.0553 - 2.667 0.436 - 153.9 1 2 0 0.0019 16 0 0 0 6.49E+07 6.17E+07 - - - 5.9175 0.9998 221125_WJC_METTL3_EV_vs_WT_F05.16078.16078.3 3.08E-05 16/48 K.TK[136.11]EVYELLDSPGK[136.11].V "sp|P22234|PUR6_HUMAN,tr|E9PBS1|E9PBS1_HUMAN" 2 1493.7948 0.75 67561 16078 3 1493.79386 498.9389 Multifunctional protein ADE2 OS=Homo sapiens OX=9606 GN=PAICS PE=1 SV=3 4.68 2823.1 - 3.77E+06 - - - -0.646 - 2.649 0.46 - 410.6 1 2 1 -0.001 13 0 0 0 5.66E+07 7.57E+07 - - - 6.3096 0.9061 221125_WJC_METTL3_EV_vs_WT_F05.16080.16080.3 0.179 Jul-48 K.EMNPALGIDC[160.03]LHK[136.11].G "sp|P48643|TCPE_HUMAN,tr|E9PCA1|E9PCA1_HUMAN,tr|B7ZAR1|B7ZAR1_HUMAN,tr|E7ENZ3|E7ENZ3_HUMAN" 4 1504.7258 0.24 67563 16080 3 1504.718096 502.5825 T-complex protein 1 subunit epsilon OS=Homo sapiens OX=9606 GN=CCT5 PE=1 SV=1 5.32 2823.3 - 1.52E+06 - - - -5.0999 - 1.365 0.246 - 41.7 1 2 0 -0.0077 13 0 0 0 7.20E+06 3.04E+07 - - - 2.1242 1 221125_WJC_METTL3_EV_vs_WT_F05.16082.16082.2 1.21E-08 13/36 K.EEDGSLSLDGADSTGVVAK.L "sp|Q13263|TIF1B_HUMAN,tr|M0R0K9|M0R0K9_HUMAN" 2 1848.8589 0.5 67565 16082 2 1848.857428 925.4367 Transcription intermediary factor 1-beta OS=Homo sapiens OX=9606 GN=TRIM28 PE=1 SV=5 3.77 2823.5 - 349761 - - - -0.7864 - 2.726 0.656 - 480.5 1 2 0 -0.0015 19 0 0 0 5.11E+06 1.02E+07 - - - 6.3513 0.7665 221125_WJC_METTL3_EV_vs_WT_F05.16084.16084.3 0.346 Jul-40 K.AVLFC[160.03]LSEDK[136.11]K[136.11].N "sp|P23528|COF1_HUMAN,tr|E9PP50|E9PP50_HUMAN,tr|G3V1A4|G3V1A4_HUMAN,tr|E9PQB7|E9PQB7_HUMAN,tr|E9PK25|E9PK25_HUMAN,tr|E9PLJ3|E9PLJ3_HUMAN,tr|E9PS23|E9PS23_HUMAN" 7 1324.7032 2.29 67567 16084 3 1324.699261 442.575 Cofilin-1 OS=Homo sapiens OX=9606 GN=CFL1 PE=1 SV=3 6.1 2823.8 - 328960 - - - -2.9539 - 1.324 0.133 - 55.5 3 2 0 -0.0039 11 0 0 0 1.58E+07 6.89E+06 - - - 0.5982 0.9962 221125_WJC_METTL3_EV_vs_WT_F05.16087.16087.3 1.41E-07 16/52 M.TFTTFDLGGHEQAR[166.11].R "sp|Q9NR31|SAR1A_HUMAN,tr|Q5SQT8|Q5SQT8_HUMAN" 2 1588.7509 1.06 67568 16087 3 1588.747156 530.5909 GTP-binding protein SAR1a OS=Homo sapiens OX=9606 GN=SAR1A PE=1 SV=1 5.29 2824.2 - 2.43E+06 - - - -2.3817 - 3.221 0.522 - 252.3 1 1 0 -0.0038 14 0 0 0 4.31E+07 4.06E+07 - - - 7.4672 0.9996 221125_WJC_METTL3_EV_vs_WT_F05.16089.16089.2 3.28E-05 14/28 K.NQLTSNPENTVFDAK[136.11].R "sp|P11021|BIP_HUMAN,tr|A0A7P0TB36|A0A7P0TB36_HUMAN,tr|A0A7P0TAI0|A0A7P0TAI0_HUMAN" 3 1684.8148 0.56 67570 16089 2 1684.810172 843.4147 Endoplasmic reticulum chaperone BiP OS=Homo sapiens OX=9606 GN=HSPA5 PE=1 SV=2 4.37 2824.4 - 1.07E+06 - - - -2.7344 - 2.727 0.458 - 480.4 1 2 0 -0.0046 15 0 0 0 7.17E+07 1.29E+08 - - - 4.8888 0.9998 221125_WJC_METTL3_EV_vs_WT_F05.16092.16092.2 0.00317 28-Oct K.NQLTSNPENTVFDAK.R "sp|P11021|BIP_HUMAN,tr|A0A7P0TB36|A0A7P0TB36_HUMAN,tr|A0A7P0TAI0|A0A7P0TAI0_HUMAN" 3 1676.8006 0.57 67573 16092 2 1676.798128 839.4076 Endoplasmic reticulum chaperone BiP OS=Homo sapiens OX=9606 GN=HSPA5 PE=1 SV=2 4.37 2824.8 - 525019 - - - -1.4617 - 2.421 0.485 - 239 1 2 0 -0.0025 15 0 0 0 7.15E+07 1.26E+08 - - - 4.7962 0.9999 221125_WJC_METTL3_EV_vs_WT_F05.16098.16098.3 1.68E-08 14/64 K.TVEGAGSIAAATGFVK[136.11]K[136.11].D "sp|P37840|SYUA_HUMAN,tr|A0A669KB41|A0A669KB41_HUMAN,tr|A0A669KBH5|A0A669KBH5_HUMAN,tr|H6UYS7|H6UYS7_HUMAN,tr|E7EPV7|E7EPV7_HUMAN" 5 1621.901 1.81 67577 16098 3 1621.899511 541.641 Alpha-synuclein OS=Homo sapiens OX=9606 GN=SNCA PE=1 SV=1 8.26 2825.6 - 6.72E+06 - - - -0.9316 - 2.666 0.391 - 134.6 1 2 0 -0.0015 17 0 0 0 4.25E+08 2.35E+08 - - - 5.3761 1 221125_WJC_METTL3_EV_vs_WT_F05.16099.16099.3 1.06E-05 18/48 K.K[136.11]DNIQAMVIVPTR[166.11].E "sp|P26196|DDX6_HUMAN,tr|Q8IV96|Q8IV96_HUMAN" 2 1501.8406 1.08 67578 16099 3 1501.84465 501.6208 Probable ATP-dependent RNA helicase DDX6 OS=Homo sapiens OX=9606 GN=DDX6 PE=1 SV=2 8.75 2825.6 - 1.67E+06 - - - 2.7273 - 3.173 0.52 - 570.7 1 2 0 0.0041 13 0 0 0 2.35E+07 2.18E+07 - - - 7.467 0.9946 221125_WJC_METTL3_EV_vs_WT_F05.16100.16100.2 1.70E-06 Nov-32 K.TVEGAGSIAAATGFVK[136.11]K[136.11].D "sp|P37840|SYUA_HUMAN,tr|A0A669KB41|A0A669KB41_HUMAN,tr|A0A669KBH5|A0A669KBH5_HUMAN,tr|H6UYS7|H6UYS7_HUMAN,tr|E7EPV7|E7EPV7_HUMAN" 5 1621.901 1.64 67579 16100 2 1621.900334 811.9578 Alpha-synuclein OS=Homo sapiens OX=9606 GN=SNCA PE=1 SV=1 8.26 2825.8 - 367371 - - - -0.4242 - 1.972 0.047 - 234.2 1 2 0 -0.0007 17 0 0 0 1.78E+07 1.09E+07 - - - 1.0574 0.9999 221125_WJC_METTL3_EV_vs_WT_F05.16103.16103.3 2.47E-06 16/68 R.VVDALGNAIDGK[136.11]GPIGSK[136.11].T "sp|P25705|ATPA_HUMAN,tr|K7ERX7|K7ERX7_HUMAN,tr|K7EK77|K7EK77_HUMAN,tr|K7EJP1|K7EJP1_HUMAN,tr|K7ENJ4|K7ENJ4_HUMAN" 5 1725.9596 1.26 67581 16103 3 1725.958298 576.3271 "ATP synthase subunit alpha, mitochondrial OS=Homo sapiens OX=9606 GN=ATP5F1A PE=1 SV=1" 5.93 2826.1 - 1.77E+06 - - - -0.7538 - 2.622 0.51 - 175.6 1 2 1 -0.0013 18 0 0 0 3.60E+07 2.85E+07 - - - 6.6259 1 221125_WJC_METTL3_EV_vs_WT_F05.16105.16105.2 2.66E-06 14/24 K.TK[136.11]EVYELLDSPGK[136.11].V "sp|P22234|PUR6_HUMAN,tr|E9PBS1|E9PBS1_HUMAN" 2 1493.7948 1.06 67582 16105 2 1493.799503 747.9047 Multifunctional protein ADE2 OS=Homo sapiens OX=9606 GN=PAICS PE=1 SV=3 4.68 2826.3 - 1.00E+06 - - - 3.1316 - 2.73 0.576 - 555 1 2 1 0.0047 13 0 0 0 1.40E+07 1.32E+07 - - - 5.8714 0.9994 221125_WJC_METTL3_EV_vs_WT_F05.16106.16106.3 2.81E-06 13/52 R.SQIKNEINIDTLAR.D "sp|Q8N766|EMC1_HUMAN,tr|A0A286YEW0|A0A286YEW0_HUMAN" 2 1613.8737 4.77 67583 16106 3 1613.878487 538.9652 ER membrane protein complex subunit 1 OS=Homo sapiens OX=9606 GN=EMC1 PE=1 SV=1 5.79 2826.5 - 621311 - - - 2.9761 - 2.666 0.461 - 201 1 2 1 0.0048 14 0 0 0 1.41E+07 2.96E+06 - - - 6.2843 0.9998 221125_WJC_METTL3_EV_vs_WT_F05.16107.16107.3 0.0011 13/40 K.AVLFC[160.03]LSEDKK.N "sp|P23528|COF1_HUMAN,tr|E9PP50|E9PP50_HUMAN,tr|G3V1A4|G3V1A4_HUMAN,tr|E9PQB7|E9PQB7_HUMAN,tr|E9PK25|E9PK25_HUMAN,tr|E9PLJ3|E9PLJ3_HUMAN,tr|E9PS23|E9PS23_HUMAN" 7 1308.6748 2.29 67584 16107 3 1308.677611 437.2322 Cofilin-1 OS=Homo sapiens OX=9606 GN=CFL1 PE=1 SV=3 6.1 2826.6 - 839930 - - - 2.1678 - 2.07 0.407 - 151.2 1 2 0 0.0028 11 0 0 0 1.58E+07 6.89E+06 - - - 5.1437 0.9998 221125_WJC_METTL3_EV_vs_WT_F05.16109.16109.2 2.16E-07 16/32 K.TVEGAGSIAAATGFVKK.D "sp|P37840|SYUA_HUMAN,tr|A0A669KB41|A0A669KB41_HUMAN,tr|A0A669KBH5|A0A669KBH5_HUMAN,tr|H6UYS7|H6UYS7_HUMAN,tr|E7EPV7|E7EPV7_HUMAN" 5 1605.8726 1.64 67586 16109 2 1605.869308 803.9436 Alpha-synuclein OS=Homo sapiens OX=9606 GN=SNCA PE=1 SV=1 8.26 2826.9 - 699649 - - - -2.0637 - 3.137 0.454 - 568 1 2 0 -0.0033 17 0 0 0 1.78E+07 1.09E+07 - - - 5.204 0.9998 221125_WJC_METTL3_EV_vs_WT_F05.16110.16110.3 1.45E-06 Nov-40 K.ITLQDVVSHSK[136.11].K "sp|P46940|IQGA1_HUMAN,tr|H0YLE8|H0YLE8_HUMAN,tr|A0A0J9YXZ5|A0A0J9YXZ5_HUMAN" 3 1233.6809 0.92 67587 16110 3 1233.676281 412.2342 Ras GTPase-activating-like protein IQGAP1 OS=Homo sapiens OX=9606 GN=IQGAP1 PE=1 SV=1 6.74 2827 - 535561 - - - -3.7052 - 2.259 0.482 - 121.1 1 2 0 -0.0046 11 0 0 0 1.87E+07 2.03E+07 - - - 6.2276 0.9936 221125_WJC_METTL3_EV_vs_WT_F05.16111.16111.2 2.91E-08 Nov-34 R.C[160.03]PKPASQIGC[160.03]SAPGYLPT.S "sp|Q9BQA1|MEP50_HUMAN,tr|H0Y711|H0Y711_HUMAN" 2 1902.8968 9.31 67588 16111 2 1902.89856 952.4557 Methylosome protein 50 OS=Homo sapiens OX=9606 GN=WDR77 PE=1 SV=1 8.05 2827.1 - 477964 - - - 0.9223 - 2.153 0.639 - 166.1 1 1 0 0.0018 18 0 0 0 8.98E+06 9.65E+05 - - - 5.6455 1 221125_WJC_METTL3_EV_vs_WT_F05.16112.16112.3 2.91E-08 14/80 K.LVTEMGTYATQSALSSSRPTK.K sp|P53618|COPB_HUMAN 1 2227.1154 0.35 67589 16112 3 2227.114201 743.3791 Coatomer subunit beta OS=Homo sapiens OX=9606 GN=COPB1 PE=1 SV=3 8.59 2827.3 - 340299 - - - -0.5599 - 3.056 0.598 - 152.1 1 2 0 -0.0012 21 0 0 0 5.29E+06 1.52E+07 - - - 7.885 0.9998 221125_WJC_METTL3_EV_vs_WT_F05.16113.16113.3 1.28E-05 Dec-68 K.MGTPVPRPPQDMGQIGVR.T "sp|Q13435|SF3B2_HUMAN,tr|E9PPJ0|E9PPJ0_HUMAN,tr|H0YCG1|H0YCG1_HUMAN,tr|E9PJ04|E9PJ04_HUMAN,tr|E9PJT3|E9PJT3_HUMAN" 5 1934.9819 0.04 67590 16113 3 1934.978937 646.0012 Splicing factor 3B subunit 2 OS=Homo sapiens OX=9606 GN=SF3B2 PE=1 SV=2 9.35 2827.4 - 274549 - - - -1.5163 - 2.145 0.414 - 119.7 1 2 0 -0.0029 18 0 0 0 6.09E+06 1.45E+08 - - - 5.0552 0.9983 221125_WJC_METTL3_EV_vs_WT_F05.16119.16119.2 3.59E-05 22-Dec K.QQQFENLDQQLR.K sp|O60749|SNX2_HUMAN 1 1545.7536 1.25 67594 16119 2 1545.745988 773.8841 Sorting nexin-2 OS=Homo sapiens OX=9606 GN=SNX2 PE=1 SV=2 4.37 2828.1 - 756919 - - - -4.9044 - 2.452 0.53 - 699.3 1 2 0 -0.0076 12 0 0 0 8.62E+06 6.91E+06 - - - 5.3131 0.9996 221125_WJC_METTL3_EV_vs_WT_F05.16120.16120.3 0.0029 16/44 R.TVITEEFK[136.11]VPDK[136.11].M sp|Q96I24|FUBP3_HUMAN 1 1420.7784 1.85 67595 16120 3 1420.775864 474.6001 Far upstream element-binding protein 3 OS=Homo sapiens OX=9606 GN=FUBP3 PE=1 SV=2 4.68 2828.2 - 684778 - - - -1.818 - 3.014 0.385 - 286 1 2 1 -0.0026 12 0 0 0 3.97E+08 2.15E+08 - - - 5.8898 1 221125_WJC_METTL3_EV_vs_WT_F05.16125.16125.2 7.27E-12 15/32 R.SGGGFSSGSAGIINYQR.R sp|P04264|K2C1_HUMAN 1 1656.7856 411.57 67598 16125 2 1656.784981 829.4001 "Keratin, type II cytoskeletal 1 OS=Homo sapiens OX=9606 GN=KRT1 PE=1 SV=6" 8.46 2828.9 - 1.66E+06 - - - -0.3724 - 3.207 0.672 - 849.9 1 2 0 -0.0006 17 0 0 0 1.96E+09 4.75E+06 - - - 6.8692 0.9998 221125_WJC_METTL3_EV_vs_WT_F05.16126.16126.3 0.000146 13/52 K.NLLHSLQSSGIGSK[136.11].A sp|Q92616|GCN1_HUMAN 1 1447.7874 0.62 67599 16126 3 1447.788827 483.6031 eIF-2-alpha kinase activator GCN1 OS=Homo sapiens OX=9606 GN=GCN1 PE=1 SV=6 8.76 2829 - 579883 - - - 0.9566 - 2.031 0.367 - 162.8 1 2 0 0.0014 14 0 0 0 1.15E+07 1.84E+07 - - - 4.5142 0.988 221125_WJC_METTL3_EV_vs_WT_F05.16128.16128.3 9.88E-05 13/52 K.SGK[136.11]WEGLVYAPPGK[136.11].E "sp|Q9Y2W1|TR150_HUMAN,tr|A0A3B3ITZ9|A0A3B3ITZ9_HUMAN" 2 1503.8057 2.63 67601 16128 3 1503.797213 502.2758 Thyroid hormone receptor-associated protein 3 OS=Homo sapiens OX=9606 GN=THRAP3 PE=1 SV=2 8.22 2829.1 - 1.06E+06 - - - -5.6204 - 2.158 0.409 - 178.2 1 2 1 -0.0085 14 0 0 0 4.64E+09 1.76E+09 - - - 5.1417 1 221125_WJC_METTL3_EV_vs_WT_F05.16129.16129.3 7.80E-12 18/80 K.LVTEMGTYATQSALSSSR[166.11]PTK[136.11].K sp|P53618|COPB_HUMAN 1 2245.1379 0.36 67602 16129 3 2245.133678 749.3866 Coatomer subunit beta OS=Homo sapiens OX=9606 GN=COPB1 PE=1 SV=3 8.59 2829.2 - 666514 - - - -1.8885 - 3.525 0.679 - 289.5 1 2 0 -0.0042 21 0 0 0 5.46E+06 1.52E+07 - - - 9.1295 0.9995 221125_WJC_METTL3_EV_vs_WT_F05.16132.16132.2 1.24E-06 13/22 K.QQQFENLDQQLR[166.11].K sp|O60749|SNX2_HUMAN 1 1555.7618 1.25 67605 16132 2 1555.756626 778.8882 Sorting nexin-2 OS=Homo sapiens OX=9606 GN=SNX2 PE=1 SV=2 4.37 2829.6 - 485276 - - - -3.3508 - 2.65 0.551 - 905.7 1 2 0 -0.0052 12 0 0 0 8.62E+06 6.91E+06 - - - 5.6733 0.9919 221125_WJC_METTL3_EV_vs_WT_F05.16133.16133.3 0.0913 Nov-44 K.QQQFENLDQQLR[166.11].K sp|O60749|SNX2_HUMAN 1 1555.7618 2.89 67606 16133 3 1555.761835 519.5946 Sorting nexin-2 OS=Homo sapiens OX=9606 GN=SNX2 PE=1 SV=2 4.37 2829.7 - 427933 - - - -0.0026 - 1.337 0.232 - 123.2 1 2 0 0 12 0 0 0 1.24E+07 4.29E+06 - - - 1.9316 0.9982 221125_WJC_METTL3_EV_vs_WT_F05.16136.16136.2 0.0001 16/22 K.NKLEGLEDALQK.A "sp|P48668|K2C6C_HUMAN,sp|P04259|K2C6B_HUMAN,sp|P02538|K2C6A_HUMAN" 3 1356.7249 999 67608 16136 2 1356.724413 679.3697 "Keratin, type II cytoskeletal 6C OS=Homo sapiens OX=9606 GN=KRT6C PE=1 SV=3" 4.68 2830.1 - 4.46E+07 - - - -0.3553 - 2.901 0.341 - 938.9 1 2 1 -0.0005 12 0 0 0 1.62E+09 0.00E+00 - - - 4.3618 0.9999 221125_WJC_METTL3_EV_vs_WT_F05.16138.16138.3 6.69E-07 15/52 K.SGKWEGLVYAPPGK.E "sp|Q9Y2W1|TR150_HUMAN,tr|A0A3B3ITZ9|A0A3B3ITZ9_HUMAN" 2 1487.7773 2.63 67609 16138 3 1487.777142 496.933 Thyroid hormone receptor-associated protein 3 OS=Homo sapiens OX=9606 GN=THRAP3 PE=1 SV=2 8.22 2830.3 - 7.28E+06 - - - -0.0827 - 2.815 0.534 - 246.3 1 2 1 -0.0001 14 0 0 0 4.62E+09 1.75E+09 - - - 7.244 0.9998 221125_WJC_METTL3_EV_vs_WT_F05.16139.16139.3 1.84E-05 13/44 R.TVITEEFKVPDK.M sp|Q96I24|FUBP3_HUMAN 1 1404.75 1.85 67610 16139 3 1404.750597 469.2573 Far upstream element-binding protein 3 OS=Homo sapiens OX=9606 GN=FUBP3 PE=1 SV=2 4.68 2830.4 - 5.17E+06 - - - 0.3915 - 2.479 0.455 - 153.2 1 2 1 0.0006 12 0 0 0 3.97E+08 2.15E+08 - - - 6.1291 0.9999 221125_WJC_METTL3_EV_vs_WT_F05.16140.16140.3 2.83E-05 13/40 K.ITLQDVVSHSK.K "sp|P46940|IQGA1_HUMAN,tr|H0YLE8|H0YLE8_HUMAN,tr|A0A0J9YXZ5|A0A0J9YXZ5_HUMAN" 3 1225.6667 0.88 67611 16140 3 1225.665448 409.5628 Ras GTPase-activating-like protein IQGAP1 OS=Homo sapiens OX=9606 GN=IQGAP1 PE=1 SV=1 6.74 2830.5 - 1.32E+06 - - - -0.9823 - 2.374 0.424 - 155.6 1 2 0 -0.0012 11 0 0 0 1.78E+07 2.03E+07 - - - 5.723 1 221125_WJC_METTL3_EV_vs_WT_F05.16148.16148.2 5.77E-11 Nov-32 D.AQSLTTC[160.03]EVC[160.03]GAC[160.03]FETR[166.11].K "sp|O95785|WIZ_HUMAN,tr|A0A669KBG4|A0A669KBG4_HUMAN,tr|A0A2R8YFV2|A0A2R8YFV2_HUMAN,tr|A0A669KAV7|A0A669KAV7_HUMAN,tr|M0QXA7|M0QXA7_HUMAN,tr|A0A669KBH9|A0A669KBH9_HUMAN,tr|B9EGQ5|B9EGQ5_HUMAN" 7 1998.8473 0.81 67619 16148 2 1998.854337 1000.4309 Protein Wiz OS=Homo sapiens OX=9606 GN=WIZ PE=1 SV=2 4.53 2831.5 - 151229 - - - 3.5195 - 2.575 0.655 - 319.1 1 1 0 0.007 17 0 0 0 1.09E+06 1.34E+06 - - - 6.202 1 221125_WJC_METTL3_EV_vs_WT_F05.16152.16152.3 0.000119 22/72 K.VQASLAANTFTITGHAETK.Q "sp|P20290|BTF3_HUMAN,tr|A0A7I2V3T6|A0A7I2V3T6_HUMAN,tr|D6RDG3|D6RDG3_HUMAN,tr|A0A7I2V5Y3|A0A7I2V5Y3_HUMAN,tr|H0Y9Y1|H0Y9Y1_HUMAN,tr|A0A7I2YQL2|A0A7I2YQL2_HUMAN" 6 1959.0062 0.99 67621 16152 3 1959.008145 654.0093 Transcription factor BTF3 OS=Homo sapiens OX=9606 GN=BTF3 PE=1 SV=1 6.72 2831.9 - 2.20E+06 - - - 1.0158 - 3.212 0.508 - 521.9 1 2 0 0.002 19 0 0 0 2.44E+08 2.45E+08 - - - 7.07 1 221125_WJC_METTL3_EV_vs_WT_F05.16153.16153.2 0.000906 22-Dec R.EQWIQDAEEC[160.03]DR.A sp|O94906|PRP6_HUMAN 1 1577.6416 4.67 67622 16153 2 1577.64194 789.8281 Pre-mRNA-processing factor 6 OS=Homo sapiens OX=9606 GN=PRPF6 PE=1 SV=1 3.83 2832.1 - 1.10E+06 - - - 0.1927 - 2.446 0.603 - 634.3 1 2 0 0.0003 12 0 0 0 1.59E+07 3.41E+06 - - - 5.8481 1 221125_WJC_METTL3_EV_vs_WT_F05.16154.16154.3 6.11E-08 17/72 K.VQASLAANTFTITGHAETK[136.11].Q "sp|P20290|BTF3_HUMAN,tr|A0A7I2V3T6|A0A7I2V3T6_HUMAN,tr|D6RDG3|D6RDG3_HUMAN,tr|A0A7I2V5Y3|A0A7I2V5Y3_HUMAN,tr|H0Y9Y1|H0Y9Y1_HUMAN,tr|A0A7I2YQL2|A0A7I2YQL2_HUMAN" 6 1967.0204 1 67623 16154 3 1967.018991 656.6807 Transcription factor BTF3 OS=Homo sapiens OX=9606 GN=BTF3 PE=1 SV=1 6.72 2832.1 - 3.04E+06 - - - -0.6934 - 3.346 0.608 - 381.3 1 2 0 -0.0014 19 0 0 0 2.45E+08 2.46E+08 - - - 8.2855 1 221125_WJC_METTL3_EV_vs_WT_F05.16156.16156.3 2.68E-09 18/80 R.SSPYGTLKPEEMSGPGLAEPK.A "sp|Q5JSZ5|PRC2B_HUMAN,tr|A0A804HKC3|A0A804HKC3_HUMAN,tr|A0A804HJR4|A0A804HJR4_HUMAN" 3 2174.0565 2.17 67625 16156 3 2174.05739 725.6928 Protein PRRC2B OS=Homo sapiens OX=9606 GN=PRRC2B PE=1 SV=2 4.78 2832.4 - 756303 - - - 0.3928 - 3.464 0.592 - 315.7 1 2 0 0.0009 21 0 0 0 2.09E+07 9.64E+06 - - - 8.1186 1 221125_WJC_METTL3_EV_vs_WT_F05.16157.16157.2 1.93E-08 15/26 K.SGKWEGLVYAPPGK.E "sp|Q9Y2W1|TR150_HUMAN,tr|A0A3B3ITZ9|A0A3B3ITZ9_HUMAN" 2 1487.7773 2.61 67626 16157 2 1487.779269 744.8959 Thyroid hormone receptor-associated protein 3 OS=Homo sapiens OX=9606 GN=THRAP3 PE=1 SV=2 8.22 2832.5 - 687657 - - - 1.347 - 3.09 0.62 - 461.9 1 2 1 0.002 14 0 0 0 2.88E+08 1.10E+08 - - - 6.4508 0.9995 221125_WJC_METTL3_EV_vs_WT_F05.16159.16159.3 6.73E-05 15/44 K.ADWWTNTAHYNR.E "sp|Q6P2Q9|PRP8_HUMAN,tr|I3L0J9|I3L0J9_HUMAN" 2 1533.6749 1 67628 16159 3 1533.670096 512.2323 Pre-mRNA-processing-splicing factor 8 OS=Homo sapiens OX=9606 GN=PRPF8 PE=1 SV=2 6.79 2832.8 - 442061 - - - -3.1486 - 2.493 0.355 - 230.5 1 2 0 -0.0048 12 0 0 0 1.54E+07 1.54E+07 - - - 5.0286 0.9999 221125_WJC_METTL3_EV_vs_WT_F05.16160.16160.3 0.00018 Sep-48 K.NNPVHLITEEDLK.Q sp|O94874|UFL1_HUMAN 1 1520.7835 1.7 67629 16160 3 1520.783716 507.9351 E3 UFM1-protein ligase 1 OS=Homo sapiens OX=9606 GN=UFL1 PE=1 SV=2 4.65 2832.9 - 424017 - - - 0.1604 - 2.058 0.429 - 109.6 1 2 0 0.0002 13 0 0 0 3.33E+07 1.95E+07 - - - 5.2797 1 221125_WJC_METTL3_EV_vs_WT_F05.16164.16164.2 1.43E-05 15/28 K.VNQIGSVTESIQAC[160.03]K[136.11].L "sp|P13929|ENOB_HUMAN,sp|P06733|ENOA_HUMAN,tr|A0A2R8Y6G6|A0A2R8Y6G6_HUMAN" 3 1640.8283 1.51 67633 16164 2 1640.825042 821.4214 Beta-enolase OS=Homo sapiens OX=9606 GN=ENO3 PE=1 SV=5 5.97 2833.4 - 220467 - - - -1.9984 - 3.011 0.583 - 781.5 1 2 0 -0.0033 15 0 0 0 1.52E+08 1.01E+08 - - - 6.056 0.9801 221125_WJC_METTL3_EV_vs_WT_F05.16169.16169.3 0.0204 Nov-52 R.STSHK[136.11]PDEIYGMIE.R sp|Q86U44|MTA70_HUMAN 1 1613.7487 0.01 67636 16169 3 1613.747301 538.9235 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 4.89 2834.1 - 1.66E+06 - - - -0.8502 - 2.286 0.346 - 89.6 1 1 0 -0.0014 14 0 0 0 1.36E+05 2.42E+07 - - - 4.5944 1 221125_WJC_METTL3_EV_vs_WT_F05.16170.16170.2 4.94E-06 19/26 K.SGK[136.11]WEGLVYAPPGK[136.11].E "sp|Q9Y2W1|TR150_HUMAN,tr|A0A3B3ITZ9|A0A3B3ITZ9_HUMAN" 2 1503.8057 2.62 67637 16170 2 1503.804684 752.9101 Thyroid hormone receptor-associated protein 3 OS=Homo sapiens OX=9606 GN=THRAP3 PE=1 SV=2 8.22 2834.2 - 1.51E+06 - - - -0.6523 - 3.328 0.587 - 856.4 1 2 1 -0.001 14 0 0 0 2.88E+08 1.10E+08 - - - 6.3936 0.9982 221125_WJC_METTL3_EV_vs_WT_F05.16171.16171.2 4.05E-05 22-Dec R.TVITEEFK[136.11]VPDK[136.11].M sp|Q96I24|FUBP3_HUMAN 1 1420.7784 1.55 67638 16171 2 1420.778732 711.3965 Far upstream element-binding protein 3 OS=Homo sapiens OX=9606 GN=FUBP3 PE=1 SV=2 4.68 2834.3 - 941534 - - - 0.2006 - 2.445 0.409 - 387.7 1 2 1 0.0003 12 0 0 0 2.80E+07 1.81E+07 - - - 4.4142 0.9998 221125_WJC_METTL3_EV_vs_WT_F05.16172.16172.3 0.00278 Nov-52 K.QPAEHLQLLEEAAK.E "sp|P33992|MCM5_HUMAN,tr|B1AHA9|B1AHA9_HUMAN" 2 1575.8257 0.43 67639 16172 3 1575.829028 526.2825 DNA replication licensing factor MCM5 OS=Homo sapiens OX=9606 GN=MCM5 PE=1 SV=5 4.75 2834.4 - 740676 - - - 2.1303 - 2.509 0.365 - 182.3 1 2 0 0.0034 14 0 0 0 8.03E+06 1.88E+07 - - - 5.0531 0.9999 221125_WJC_METTL3_EV_vs_WT_F05.16173.16173.3 1.44E-05 16/80 R.SSPYGTLK[136.11]PEEMSGPGLAEPK[136.11].A "sp|Q5JSZ5|PRC2B_HUMAN,tr|A0A804HKC3|A0A804HKC3_HUMAN,tr|A0A804HJR4|A0A804HJR4_HUMAN" 3 2190.0849 2.17 67640 16173 3 2190.081693 731.0356 Protein PRRC2B OS=Homo sapiens OX=9606 GN=PRRC2B PE=1 SV=2 4.78 2834.6 - 639313 - - - -1.4808 - 2.271 0.478 - 86.7 1 2 0 -0.0032 21 0 0 0 2.09E+07 9.64E+06 - - - 5.8348 0.7963 221125_WJC_METTL3_EV_vs_WT_F05.16174.16174.2 0.227 18-Nov V.ITEEFK[136.11]VPDK[136.11].M sp|Q96I24|FUBP3_HUMAN 1 1220.6624 1.57 67641 16174 2 1220.663508 611.3385 Far upstream element-binding protein 3 OS=Homo sapiens OX=9606 GN=FUBP3 PE=1 SV=2 4.68 2834.7 - 540907 - - - 0.9454 - 2.253 0.31 - 328.5 1 1 1 0.0012 10 0 0 0 1.21E+07 7.71E+06 - - - 3.5976 1 221125_WJC_METTL3_EV_vs_WT_F05.16181.16181.2 1.87E-09 15/28 K.VNQIGSVTESIQAC[160.03]K.L "sp|P13929|ENOB_HUMAN,sp|P06733|ENOA_HUMAN,tr|A0A2R8Y6G6|A0A2R8Y6G6_HUMAN" 3 1632.8141 1.51 67646 16181 2 1632.812333 817.4143 Beta-enolase OS=Homo sapiens OX=9606 GN=ENO3 PE=1 SV=5 5.97 2835.6 - 3.11E+06 - - - -1.095 - 3.134 0.637 - 742.3 1 2 0 -0.0018 15 0 0 0 1.52E+08 1.01E+08 - - - 6.5537 0.999 221125_WJC_METTL3_EV_vs_WT_F05.16182.16182.2 3.17E-06 16/22 R.TVITEEFKVPDK.M sp|Q96I24|FUBP3_HUMAN 1 1404.75 1.55 67647 16182 2 1404.750774 703.3823 Far upstream element-binding protein 3 OS=Homo sapiens OX=9606 GN=FUBP3 PE=1 SV=2 4.68 2835.7 - 1.73E+06 - - - 0.5175 - 2.711 0.533 - 734.5 1 2 1 0.0007 12 0 0 0 2.80E+07 1.81E+07 - - - 5.6016 0.9997 221125_WJC_METTL3_EV_vs_WT_F05.16183.16183.3 5.15E-06 13/44 K.YYVTIIDAPGHR[166.11].D "sp|P68104|EF1A1_HUMAN,sp|Q5VTE0|EF1A3_HUMAN,tr|A0A7I2V659|A0A7I2V659_HUMAN,tr|A0A7I2V3H3|A0A7I2V3H3_HUMAN,tr|Q5JR01|Q5JR01_HUMAN,tr|A0A7I2V5N4|A0A7I2V5N4_HUMAN,tr|A0A087WVQ9|A0A087WVQ9_HUMAN,tr|A6PW80|A6PW80_HUMAN,tr|A0A087WV01|A0A087WV01_HUMAN" 9 1413.728 0.4 67648 16183 3 1413.722077 472.2499 Elongation factor 1-alpha 1 OS=Homo sapiens OX=9606 GN=EEF1A1 PE=1 SV=1 6.74 2835.8 - 1.52E+06 - - - -4.2038 - 2.257 0.52 - 176 1 2 0 -0.0059 12 0 0 0 1.32E+07 3.31E+07 - - - 6.5922 1 221125_WJC_METTL3_EV_vs_WT_F05.16184.16184.3 6.94E-05 15/44 K.ADWWTNTAHYNR[166.11].E "sp|Q6P2Q9|PRP8_HUMAN,tr|I3L0J9|I3L0J9_HUMAN" 2 1543.6832 1.01 67649 16184 3 1543.679815 515.5683 Pre-mRNA-processing-splicing factor 8 OS=Homo sapiens OX=9606 GN=PRPF8 PE=1 SV=2 6.79 2835.8 - 918270 - - - -2.1896 - 2.361 0.539 - 254.5 1 2 0 -0.0034 12 0 0 0 1.55E+07 1.54E+07 - - - 6.9296 1 221125_WJC_METTL3_EV_vs_WT_F05.16185.16185.2 1.29E-06 16/24 K.QSLEASLAETEGR.Y "sp|P13645|K1C10_HUMAN,tr|A0A1B0GVI3|A0A1B0GVI3_HUMAN" 2 1389.6736 120.16 67650 16185 2 1389.671687 695.8441 "Keratin, type I cytoskeletal 10 OS=Homo sapiens OX=9606 GN=KRT10 PE=1 SV=6" 4.25 2836 - 789726 - - - -1.3672 - 3.131 0.545 - 1271.9 1 2 0 -0.0019 13 0 0 0 6.20E+07 5.16E+05 - - - 5.9951 0.9705 221125_WJC_METTL3_EV_vs_WT_F05.16186.16186.3 0.271 16/52 K.NLLHSLQSSGIGSK.A sp|Q92616|GCN1_HUMAN 1 1439.7732 0.7 67651 16186 3 1439.766229 480.9317 eIF-2-alpha kinase activator GCN1 OS=Homo sapiens OX=9606 GN=GCN1 PE=1 SV=6 8.76 2836.1 - 633701 - - - -4.8709 - 2.118 0.204 - 345.9 1 2 0 -0.007 14 0 0 0 1.27E+07 1.82E+07 - - - 2.8069 1 221125_WJC_METTL3_EV_vs_WT_F05.16188.16188.2 4.79E-11 17/32 R.ADALQAGASQFETSAAK.L "sp|Q15836|VAMP3_HUMAN,sp|P63027|VAMP2_HUMAN,tr|F8WCA0|F8WCA0_HUMAN,tr|L7N2F9|L7N2F9_HUMAN,tr|K7ENK9|K7ENK9_HUMAN,tr|K7EKX0|K7EKX0_HUMAN,tr|J3QRU4|J3QRU4_HUMAN" 7 1664.8006 1.36 67653 16188 2 1664.800918 833.4076 Vesicle-associated membrane protein 3 OS=Homo sapiens OX=9606 GN=VAMP3 PE=1 SV=3 4.37 2836.3 - 410384 - - - 0.2036 - 3.196 0.549 - 736.6 1 2 0 0.0003 17 0 0 0 2.40E+07 1.77E+07 - - - 5.9524 1 221125_WJC_METTL3_EV_vs_WT_F05.16189.16189.3 1.28E-09 21/56 K.HLEINPDHPIVETLR[166.11].Q sp|P08238|HS90B_HUMAN 1 1791.9507 1.11 67654 16189 3 1791.947182 598.3242 Heat shock protein HSP 90-beta OS=Homo sapiens OX=9606 GN=HSP90AB1 PE=1 SV=4 5.27 2836.5 - 372000 - - - -1.9649 - 3.677 0.601 - 538.3 1 2 0 -0.0035 15 0 0 0 2.13E+08 1.93E+08 - - - 8.6372 0.9858 221125_WJC_METTL3_EV_vs_WT_F05.16198.16198.3 3.08E-05 Oct-72 K.PSTASAVPELATDPELEK[136.11]K[136.11].L "sp|Q86U44|MTA70_HUMAN,tr|B4E349|B4E349_HUMAN,tr|F5H6D8|F5H6D8_HUMAN,tr|H0YFV6|H0YFV6_HUMAN,tr|B4DTN4|B4DTN4_HUMAN" 5 1998.0492 0.18 67661 16198 3 1998.044554 667.0237 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 4.41 2837.6 - 248491 - - - -2.3263 - 2.155 0.474 - 93.8 1 1 0 -0.0046 19 0 0 0 6.70E+05 3.66E+06 - - - 5.7097 0.9999 221125_WJC_METTL3_EV_vs_WT_F05.16202.16202.3 1.86E-05 Dec-56 K.VNQIGSVTESIQAC[160.03]K[136.11].L "sp|P13929|ENOB_HUMAN,sp|P06733|ENOA_HUMAN,tr|A0A2R8Y6G6|A0A2R8Y6G6_HUMAN" 3 1640.8283 2.63 67663 16202 3 1640.828637 547.9501 Beta-enolase OS=Homo sapiens OX=9606 GN=ENO3 PE=1 SV=5 5.97 2838.1 - 2.11E+06 - - - 0.1926 - 2.621 0.415 - 244.2 1 2 0 0.0003 15 0 0 0 8.14E+07 3.10E+07 - - - 5.681 0.7643 221125_WJC_METTL3_EV_vs_WT_F05.16203.16203.2 0.196 12-Aug D.K[136.11]GSVWDR[166.11].M sp|Q6P179|ERAP2_HUMAN 1 864.4573 0.01 67664 16203 2 864.457302 433.2359 Endoplasmic reticulum aminopeptidase 2 OS=Homo sapiens OX=9606 GN=ERAP2 PE=1 SV=2 8.75 2838.2 - 1.08E+06 - - - 0.0359 - 1.248 0.182 - 131.3 1 1 0 0 7 0 0 0 1.03E+05 1.92E+07 - - - 1.0872 0.9938 221125_WJC_METTL3_EV_vs_WT_F05.16204.16204.3 0.00515 Oct-68 K.EAYMGNVLQGGEGQAPTR.Q "sp|P24752|THIL_HUMAN,tr|A0A5F9ZHL7|A0A5F9ZHL7_HUMAN,tr|A0A5F9ZHJ7|A0A5F9ZHJ7_HUMAN,tr|A0A5F9ZHH9|A0A5F9ZHH9_HUMAN,tr|A0A5F9ZHL1|A0A5F9ZHL1_HUMAN,tr|E9PRQ6|E9PRQ6_HUMAN,tr|H0YEL7|H0YEL7_HUMAN" 7 1876.8738 3.05 67665 16204 3 1876.871949 626.6319 "Acetyl-CoA acetyltransferase, mitochondrial OS=Homo sapiens OX=9606 GN=ACAT1 PE=1 SV=1" 4.53 2838.3 - 997354 - - - -0.9654 - 2.067 0.157 - 79.4 1 2 0 -0.0018 18 0 0 0 1.93E+08 6.31E+07 - - - 2.098 1 221125_WJC_METTL3_EV_vs_WT_F05.16205.16205.2 4.67E-05 15/32 R.ADALQAGASQFETSAAK[136.11].L "sp|Q15836|VAMP3_HUMAN,sp|P63027|VAMP2_HUMAN,tr|F8WCA0|F8WCA0_HUMAN,tr|L7N2F9|L7N2F9_HUMAN,tr|K7ENK9|K7ENK9_HUMAN,tr|K7EKX0|K7EKX0_HUMAN,tr|J3QRU4|J3QRU4_HUMAN" 7 1672.8148 1.36 67666 16205 2 1672.809835 837.4147 Vesicle-associated membrane protein 3 OS=Homo sapiens OX=9606 GN=VAMP3 PE=1 SV=3 4.37 2838.4 - 898050 - - - -2.9555 - 2.992 0.543 - 517.4 1 2 0 -0.0049 17 0 0 0 2.40E+07 1.77E+07 - - - 5.7445 1 221125_WJC_METTL3_EV_vs_WT_F05.16207.16207.2 3.23E-08 13/22 R.AEEENEFQIPGR[166.11].T sp|Q8N0X7|SPART_HUMAN 1 1427.6556 1.18 67668 16207 2 1427.654259 714.8351 Spartin OS=Homo sapiens OX=9606 GN=SPART PE=1 SV=1 4.09 2838.7 - 824721 - - - -0.9694 - 2.648 0.639 - 511.8 1 2 0 -0.0014 12 0 0 0 2.50E+07 2.11E+07 - - - 6.3225 1 221125_WJC_METTL3_EV_vs_WT_F05.16208.16208.4 4.33E-09 18/84 K.HLEINPDHPIVETLR.Q sp|P08238|HS90B_HUMAN 1 1781.9424 1.13 67669 16208 4 1781.941361 446.4929 Heat shock protein HSP 90-beta OS=Homo sapiens OX=9606 GN=HSP90AB1 PE=1 SV=4 5.27 2838.8 - 759765 - - - -0.6016 - 3.178 0.546 - 325 1 2 0 -0.0011 15 0 0 0 7.28E+07 6.47E+07 - - - 4.3918 0.9999 221125_WJC_METTL3_EV_vs_WT_F05.16210.16210.4 3.50E-07 15/84 K.HLEINPDHPIVETLR[166.11].Q sp|P08238|HS90B_HUMAN 1 1791.9507 1.13 67671 16210 4 1791.946172 448.995 Heat shock protein HSP 90-beta OS=Homo sapiens OX=9606 GN=HSP90AB1 PE=1 SV=4 5.27 2839 - 592769 - - - -2.5285 - 2.515 0.477 - 231.3 1 2 0 -0.0045 15 0 0 0 7.30E+07 6.48E+07 - - - 3.7066 1 221125_WJC_METTL3_EV_vs_WT_F05.16211.16211.2 8.61E-13 17/34 K.EAYMGNVLQGGEGQAPTR[166.11].Q "sp|P24752|THIL_HUMAN,tr|A0A5F9ZHL7|A0A5F9ZHL7_HUMAN,tr|A0A5F9ZHJ7|A0A5F9ZHJ7_HUMAN,tr|A0A5F9ZHH9|A0A5F9ZHH9_HUMAN,tr|A0A5F9ZHL1|A0A5F9ZHL1_HUMAN,tr|E9PRQ6|E9PRQ6_HUMAN,tr|H0YEL7|H0YEL7_HUMAN" 7 1886.882 1.38 67672 16211 2 1886.879244 944.4483 "Acetyl-CoA acetyltransferase, mitochondrial OS=Homo sapiens OX=9606 GN=ACAT1 PE=1 SV=1" 4.53 2839.2 - 445519 - - - -1.477 - 3.378 0.738 - 837.6 1 2 0 -0.0028 18 0 0 0 7.82E+07 5.67E+07 - - - 7.4837 1 221125_WJC_METTL3_EV_vs_WT_F05.16212.16212.2 1.63E-12 15/34 K.EAYMGNVLQGGEGQAPTR.Q "sp|P24752|THIL_HUMAN,tr|A0A5F9ZHL7|A0A5F9ZHL7_HUMAN,tr|A0A5F9ZHJ7|A0A5F9ZHJ7_HUMAN,tr|A0A5F9ZHH9|A0A5F9ZHH9_HUMAN,tr|A0A5F9ZHL1|A0A5F9ZHL1_HUMAN,tr|E9PRQ6|E9PRQ6_HUMAN,tr|H0YEL7|H0YEL7_HUMAN" 7 1876.8738 1.38 67673 16212 2 1876.872657 939.4442 "Acetyl-CoA acetyltransferase, mitochondrial OS=Homo sapiens OX=9606 GN=ACAT1 PE=1 SV=1" 4.53 2839.3 - 442159 - - - -0.5882 - 3.162 0.597 - 566.6 1 2 0 -0.0011 18 0 0 0 7.82E+07 5.67E+07 - - - 6.2804 0.9902 221125_WJC_METTL3_EV_vs_WT_F05.16217.16217.3 0.0599 Nov-36 R.K[136.11]QVEEIFNLK[136.11].F "sp|P78347|GTF2I_HUMAN,tr|A0A494C0Q7|A0A494C0Q7_HUMAN,tr|A0A494C1K3|A0A494C1K3_HUMAN" 3 1262.7205 1.4 67676 16217 3 1262.718987 421.9141 General transcription factor II-I OS=Homo sapiens OX=9606 GN=GTF2I PE=1 SV=2 6.14 2839.8 - 2.87E+06 - - - -1.2283 - 2.155 0.099 - 288.4 1 2 0 -0.0016 10 0 0 0 2.43E+08 1.74E+08 - - - 1.8856 1 221125_WJC_METTL3_EV_vs_WT_F05.16218.16218.2 4.48E-06 15/22 R.AEEENEFQIPGR.T sp|Q8N0X7|SPART_HUMAN 1 1417.6474 1.18 67677 16218 2 1417.646873 709.831 Spartin OS=Homo sapiens OX=9606 GN=SPART PE=1 SV=1 4.09 2839.9 - 1.10E+06 - - - -0.3527 - 2.8 0.613 - 736.7 1 2 0 -0.0005 12 0 0 0 2.50E+07 2.11E+07 - - - 6.2776 0.829 221125_WJC_METTL3_EV_vs_WT_F05.16220.16220.3 0.295 Aug-56 R.EELGFRPEYSASQLK.G "sp|P09874|PARP1_HUMAN,tr|A0A7I2V5E9|A0A7I2V5E9_HUMAN,tr|A0A7I2V625|A0A7I2V625_HUMAN,tr|A0A7I2V3E1|A0A7I2V3E1_HUMAN" 4 1752.8683 0.19 67679 16220 3 1752.86796 585.2967 Poly [ADP-ribose] polymerase 1 OS=Homo sapiens OX=9606 GN=PARP1 PE=1 SV=4 4.79 2840.2 - 322066 - - - -0.174 - 1.685 0.019 - 66.6 1 2 0 -0.0003 15 0 0 0 7.39E+06 3.88E+07 - - - 0.1132 0.9948 221125_WJC_METTL3_EV_vs_WT_F05.16224.16224.3 0.000181 Nov-36 R.KQVEEIFNLK.F "sp|P78347|GTF2I_HUMAN,tr|A0A494C0Q7|A0A494C0Q7_HUMAN,tr|A0A494C1K3|A0A494C1K3_HUMAN" 3 1246.6921 1.4 67681 16224 3 1246.690355 416.5713 General transcription factor II-I OS=Homo sapiens OX=9606 GN=GTF2I PE=1 SV=2 6.14 2840.7 - 6.76E+06 - - - -1.4302 - 2.213 0.133 - 274.4 1 2 0 -0.0018 10 0 0 0 2.44E+08 1.75E+08 - - - 2.3422 0.9999 221125_WJC_METTL3_EV_vs_WT_F05.16225.16225.3 2.23E-08 14/52 K.QMADTGKLNTLLQR.A "sp|Q00839|HNRPU_HUMAN,tr|A0A1W2PQL0|A0A1W2PQL0_HUMAN,tr|A0A1W2PPE9|A0A1W2PPE9_HUMAN,tr|A0A1W2PPL4|A0A1W2PPL4_HUMAN,tr|A0A1W2PQ74|A0A1W2PQ74_HUMAN,tr|Q5RI18|Q5RI18_HUMAN,tr|A0A1W2PP35|A0A1W2PP35_HUMAN,tr|A0A1W2PPS1|A0A1W2PPS1_HUMAN,tr|A0A1W2PRZ7|A0A1W2PRZ7_HUMAN,tr|A0A1W2PPH7|A0A1W2PPH7_HUMAN,tr|A0A1W2PQD4|A0A1W2PQD4_HUMAN,tr|A0A1W2PP34|A0A1W2PP34_HUMAN,tr|A0A1X7SBS1|A0A1X7SBS1_HUMAN" 13 1587.8403 0.58 67682 16225 3 1587.840357 530.2874 Heterogeneous nuclear ribonucleoprotein U OS=Homo sapiens OX=9606 GN=HNRNPU PE=1 SV=6 8.75 2840.8 - 1.83E+06 - - - 0.051 - 2.707 0.535 - 289.4 1 2 1 0.0001 14 0 0 0 7.41E+07 1.28E+08 - - - 7.1512 0.9999 221125_WJC_METTL3_EV_vs_WT_F05.16226.16226.3 0.000132 14/48 K.QSLEASLAETEGR.Y "sp|P13645|K1C10_HUMAN,tr|A0A1B0GVI3|A0A1B0GVI3_HUMAN" 2 1389.6736 999 67683 16226 3 1389.673026 464.2318 "Keratin, type I cytoskeletal 10 OS=Homo sapiens OX=9606 GN=KRT10 PE=1 SV=6" 4.25 2840.9 - 1.36E+06 - - - -0.4037 - 2.417 0.415 - 360.8 1 2 0 -0.0006 13 0 0 0 1.55E+07 0.00E+00 - - - 5.5595 0.9998 221125_WJC_METTL3_EV_vs_WT_F05.16231.16231.2 0.000769 17/18 R.KQVEEIFNLK.F "sp|P78347|GTF2I_HUMAN,tr|A0A494C0Q7|A0A494C0Q7_HUMAN,tr|A0A494C1K3|A0A494C1K3_HUMAN" 3 1246.6921 1.49 67686 16231 2 1246.691559 624.3533 General transcription factor II-I OS=Homo sapiens OX=9606 GN=GTF2I PE=1 SV=2 6.14 2841.5 - 4.17E+06 - - - -0.4644 - 3.391 0.206 - 1139.5 1 2 0 -0.0006 10 0 0 0 1.30E+08 8.73E+07 - - - 3.9709 1 221125_WJC_METTL3_EV_vs_WT_F05.16233.16233.3 6.36E-12 19/60 R.VTELFMDNKNELDQC[160.03]K.S "sp|P52732|KIF11_HUMAN,tr|A0A7I2YQY4|A0A7I2YQY4_HUMAN,tr|A0A7I2V3A9|A0A7I2V3A9_HUMAN,tr|A0A7I2V3V3|A0A7I2V3V3_HUMAN" 4 1982.9078 4.29 67688 16233 3 1982.90505 661.9765 Kinesin-like protein KIF11 OS=Homo sapiens OX=9606 GN=KIF11 PE=1 SV=2 4.32 2841.7 - 949537 - - - -1.3682 - 3.849 0.615 - 624.2 1 2 1 -0.0027 16 0 0 0 2.56E+08 5.98E+07 - - - 8.8542 0.9988 221125_WJC_METTL3_EV_vs_WT_F05.16234.16234.3 1.48E-09 16/56 H.VLC[160.03]HNC[160.03]AVEFNFGQK.E "sp|Q00839|HNRPU_HUMAN,tr|A0A1W2PQL0|A0A1W2PQL0_HUMAN,tr|A0A1W2PPL4|A0A1W2PPL4_HUMAN,tr|A0A1W2PQ74|A0A1W2PQ74_HUMAN,tr|Q5RI18|Q5RI18_HUMAN,tr|A0A1W2PP35|A0A1W2PP35_HUMAN,tr|A0A1W2PPS1|A0A1W2PPS1_HUMAN,tr|A0A1W2PRZ7|A0A1W2PRZ7_HUMAN,tr|A0A1W2PPH7|A0A1W2PPH7_HUMAN,tr|A0A1W2PP34|A0A1W2PP34_HUMAN,tr|A0A1X7SBS1|A0A1X7SBS1_HUMAN" 11 1821.8291 1.02 67689 16234 3 1821.82718 608.2836 Heterogeneous nuclear ribonucleoprotein U OS=Homo sapiens OX=9606 GN=HNRNPU PE=1 SV=6 6.7 2841.8 - 326489 - - - -1.0319 - 2.829 0.604 - 320.9 1 1 0 -0.0019 15 0 0 0 5.39E+07 5.30E+07 - - - 7.987 0.9566 221125_WJC_METTL3_EV_vs_WT_F05.16237.16237.3 6.70E-09 20/96 K.LVQDVANNTNEEAGDGTTTATVLAR[166.11].S "sp|P10809|CH60_HUMAN,tr|C9JL25|C9JL25_HUMAN,tr|A0A7I2V2X6|A0A7I2V2X6_HUMAN,tr|A0A7I2YQK6|A0A7I2YQK6_HUMAN,tr|A0A7I2V599|A0A7I2V599_HUMAN,tr|E7EXB4|E7EXB4_HUMAN,tr|A0A7I2YQ71|A0A7I2YQ71_HUMAN,tr|E7ESH4|E7ESH4_HUMAN,tr|A0A7I2V5M1|A0A7I2V5M1_HUMAN,tr|A0A7I2V5K3|A0A7I2V5K3_HUMAN,tr|A0A7I2V369|A0A7I2V369_HUMAN" 11 2569.2495 -1 67691 16237 3 2570.231377 857.4238 "60 kDa heat shock protein, mitochondrial OS=Homo sapiens OX=9606 GN=HSPD1 PE=1 SV=2" 3.92 2842.2 - 1.97E+06 - - - 382.156 - 3.377 0.604 - 242 1 2 0 0.9819 25 0 0 0 0.00E+00 0.00E+00 - - - 7.8019 0.9999 221125_WJC_METTL3_EV_vs_WT_F05.16240.16240.2 8.50E-08 30-Oct K.FDEYFSQSC[160.03]APGSDPR.S "sp|P02788|TRFL_HUMAN,tr|E7EQB2|E7EQB2_HUMAN,tr|E7ER44|E7ER44_HUMAN" 3 1861.7577 999 67693 16240 2 1861.756043 931.8861 Lactotransferrin OS=Homo sapiens OX=9606 GN=LTF PE=1 SV=6 4.03 2842.5 - 529991 - - - -0.9051 - 2.221 0.629 - 163 1 2 0 -0.0017 16 0 0 0 8.70E+06 0.00E+00 - - - 5.6481 0.9997 221125_WJC_METTL3_EV_vs_WT_F05.16242.16242.3 0.214 Dec-52 K.AC[160.03]PRPEGLNFQDLK.N "sp|P15927|RFA2_HUMAN,tr|Q5TEJ0|Q5TEJ0_HUMAN" 2 1643.809 1.33 67695 16242 3 1643.80697 548.9436 Replication protein A 32 kDa subunit OS=Homo sapiens OX=9606 GN=RPA2 PE=1 SV=1 6.11 2842.6 - 2.20E+06 - - - -1.2203 - 2.328 0.31 - 179 1 2 0 -0.002 14 0 0 0 5.44E+07 4.10E+07 - - - 4.2413 0.9988 221125_WJC_METTL3_EV_vs_WT_F05.16244.16244.3 1.49E-10 19/56 H.VLC[160.03]HNC[160.03]AVEFNFGQK[136.11].E "sp|Q00839|HNRPU_HUMAN,tr|A0A1W2PQL0|A0A1W2PQL0_HUMAN,tr|A0A1W2PPL4|A0A1W2PPL4_HUMAN,tr|A0A1W2PQ74|A0A1W2PQ74_HUMAN,tr|Q5RI18|Q5RI18_HUMAN,tr|A0A1W2PP35|A0A1W2PP35_HUMAN,tr|A0A1W2PPS1|A0A1W2PPS1_HUMAN,tr|A0A1W2PRZ7|A0A1W2PRZ7_HUMAN,tr|A0A1W2PPH7|A0A1W2PPH7_HUMAN,tr|A0A1W2PP34|A0A1W2PP34_HUMAN,tr|A0A1X7SBS1|A0A1X7SBS1_HUMAN" 11 1829.8433 1.02 67697 16244 3 1829.842515 610.955 Heterogeneous nuclear ribonucleoprotein U OS=Homo sapiens OX=9606 GN=HNRNPU PE=1 SV=6 6.7 2842.9 - 1.14E+06 - - - -0.4071 - 3.366 0.566 - 665.8 1 1 0 -0.0007 15 0 0 0 5.39E+07 5.30E+07 - - - 8.0172 1 221125_WJC_METTL3_EV_vs_WT_F05.16245.16245.3 2.88E-13 31/72 R.C[160.03]ELC[160.03]DVSC[160.03]TGADAYAAHIR.G sp|Q96KR1|ZFR_HUMAN 1 2167.9085 0.62 67698 16245 3 2167.903036 723.6434 Zinc finger RNA-binding protein OS=Homo sapiens OX=9606 GN=ZFR PE=1 SV=2 4.54 2843 - 1.07E+06 - - - -2.5246 - 4.662 0.737 - 1509.6 1 2 0 -0.0055 19 0 0 0 1.41E+07 2.27E+07 - - - 10.5374 1 221125_WJC_METTL3_EV_vs_WT_F05.16250.16250.3 2.28E-08 14/64 R.SGGGFSSGSAGIINYQR.R sp|P04264|K2C1_HUMAN 1 1656.7856 152.23 67701 16250 3 1656.785028 553.2691 "Keratin, type II cytoskeletal 1 OS=Homo sapiens OX=9606 GN=KRT1 PE=1 SV=6" 8.46 2843.7 - 4.54E+06 - - - -0.344 - 2.726 0.605 - 245.2 1 2 0 -0.0006 17 0 0 0 4.64E+08 3.05E+06 - - - 7.8185 0.9444 221125_WJC_METTL3_EV_vs_WT_F05.16251.16251.3 0.13 Sep-52 K.AC[160.03]PR[166.11]PEGLNFQDLK[136.11].N "sp|P15927|RFA2_HUMAN,tr|Q5TEJ0|Q5TEJ0_HUMAN" 2 1661.8314 1.33 67702 16251 3 1661.828262 554.9511 Replication protein A 32 kDa subunit OS=Homo sapiens OX=9606 GN=RPA2 PE=1 SV=1 6.11 2843.7 - 2.98E+06 - - - -1.916 - 1.654 0.109 - 102.9 1 2 0 -0.0032 14 0 0 0 5.32E+07 4.01E+07 - - - 1.0916 1 221125_WJC_METTL3_EV_vs_WT_F05.16252.16252.3 8.46E-12 19/60 R.VTELFMDNK[136.11]NELDQC[160.03]K[136.11].S "sp|P52732|KIF11_HUMAN,tr|A0A7I2YQY4|A0A7I2YQY4_HUMAN,tr|A0A7I2V3A9|A0A7I2V3A9_HUMAN,tr|A0A7I2V3V3|A0A7I2V3V3_HUMAN" 4 1998.9362 4.29 67703 16252 3 1998.934345 667.3193 Kinesin-like protein KIF11 OS=Homo sapiens OX=9606 GN=KIF11 PE=1 SV=2 4.32 2843.8 - 1.64E+06 - - - -0.9095 - 4.156 0.648 - 572.3 1 2 1 -0.0018 16 0 0 0 2.56E+08 5.98E+07 - - - 9.4193 1 221125_WJC_METTL3_EV_vs_WT_F05.16254.16254.3 8.78E-07 14/44 R.DGWPAMC[160.03]IHGDK[136.11].S "sp|Q92841|DDX17_HUMAN,tr|A0A5H1ZRQ2|A0A5H1ZRQ2_HUMAN,tr|A0A1X7SBZ2|A0A1X7SBZ2_HUMAN" 3 1393.5998 1.37 67705 16254 3 1393.599369 465.5406 Probable ATP-dependent RNA helicase DDX17 OS=Homo sapiens OX=9606 GN=DDX17 PE=1 SV=2 5.21 2844 - 987045 - - - -0.3387 - 2.213 0.58 - 161.5 1 2 0 -0.0005 12 0 0 0 1.92E+07 1.40E+07 - - - 7.2081 0.9999 221125_WJC_METTL3_EV_vs_WT_F05.16256.16256.3 2.67E-06 14/52 R.IKDMDLWEQQEEER.L sp|Q14152|EIF3A_HUMAN 1 1847.836 1.24 67707 16256 3 1847.835077 616.9526 Eukaryotic translation initiation factor 3 subunit A OS=Homo sapiens OX=9606 GN=EIF3A PE=1 SV=1 4.08 2844.3 - 530322 - - - -0.4876 - 2.547 0.516 - 211 1 2 1 -0.0009 14 0 0 0 1.79E+07 1.44E+07 - - - 6.7772 1 221125_WJC_METTL3_EV_vs_WT_F05.16262.16262.3 2.94E-12 18/96 K.LVQDVANNTNEEAGDGTTTATVLAR.S "sp|P10809|CH60_HUMAN,tr|C9JL25|C9JL25_HUMAN,tr|A0A7I2V2X6|A0A7I2V2X6_HUMAN,tr|A0A7I2YQK6|A0A7I2YQK6_HUMAN,tr|A0A7I2V599|A0A7I2V599_HUMAN,tr|E7EXB4|E7EXB4_HUMAN,tr|A0A7I2YQ71|A0A7I2YQ71_HUMAN,tr|E7ESH4|E7ESH4_HUMAN,tr|A0A7I2V5M1|A0A7I2V5M1_HUMAN,tr|A0A7I2V5K3|A0A7I2V5K3_HUMAN,tr|A0A7I2V369|A0A7I2V369_HUMAN" 11 2559.2413 -1 67712 16262 3 2560.223787 854.0877 "60 kDa heat shock protein, mitochondrial OS=Homo sapiens OX=9606 GN=HSPD1 PE=1 SV=2" 3.92 2845 - 4.62E+06 - - - 383.9161 - 3.805 0.713 - 394.2 1 2 0 0.9825 25 0 0 0 0.00E+00 0.00E+00 - - - 9.2915 0.9994 221125_WJC_METTL3_EV_vs_WT_F05.16264.16264.2 7.11E-05 14/18 R.K[136.11]QVEEIFNLK[136.11].F "sp|P78347|GTF2I_HUMAN,tr|A0A494C0Q7|A0A494C0Q7_HUMAN,tr|A0A494C1K3|A0A494C1K3_HUMAN" 3 1262.7205 1.49 67713 16264 2 1262.72014 632.3675 General transcription factor II-I OS=Homo sapiens OX=9606 GN=GTF2I PE=1 SV=2 6.14 2845.3 - 6.98E+06 - - - -0.3152 - 2.451 0.186 - 388.6 1 2 0 -0.0004 10 0 0 0 1.30E+08 8.73E+07 - - - 2.9171 1 221125_WJC_METTL3_EV_vs_WT_F05.16266.16266.3 4.53E-12 13/56 K.LHQEDNDYINASLIK.M sp|P18031|PTN1_HUMAN 1 1771.8741 1.97 67715 16266 3 1771.871652 591.632 Tyrosine-protein phosphatase non-receptor type 1 OS=Homo sapiens OX=9606 GN=PTPN1 PE=1 SV=1 4.54 2845.5 - 1.52E+06 - - - -1.3692 - 2.822 0.674 - 173 1 2 0 -0.0024 15 0 0 0 2.32E+07 1.18E+07 - - - 8.7608 1 221125_WJC_METTL3_EV_vs_WT_F05.16267.16267.3 2.90E-07 Dec-44 R.DGWPAMC[160.03]IHGDK.S "sp|Q92841|DDX17_HUMAN,tr|A0A5H1ZRQ2|A0A5H1ZRQ2_HUMAN,tr|A0A1X7SBZ2|A0A1X7SBZ2_HUMAN" 3 1385.5856 1.38 67716 16267 3 1385.584334 462.8692 Probable ATP-dependent RNA helicase DDX17 OS=Homo sapiens OX=9606 GN=DDX17 PE=1 SV=2 5.21 2845.6 - 1.37E+06 - - - -0.9433 - 2.326 0.59 - 103.4 1 2 0 -0.0013 12 0 0 0 1.95E+07 1.42E+07 - - - 7.4574 0.9997 221125_WJC_METTL3_EV_vs_WT_F05.16268.16268.4 1.00E-05 15/66 K.LKDYAFVHFEDR.G "sp|O43390|HNRPR_HUMAN,tr|B4DT28|B4DT28_HUMAN,tr|A0A6Q8PH31|A0A6Q8PH31_HUMAN,tr|A0A6Q8PH35|A0A6Q8PH35_HUMAN" 4 1538.7518 1.32 67717 16268 4 1538.749703 385.6952 Heterogeneous nuclear ribonucleoprotein R OS=Homo sapiens OX=9606 GN=HNRNPR PE=1 SV=1 5.38 2845.6 - 1.36E+06 - - - -1.3485 - 2.397 0.443 - 269 1 2 1 -0.0021 12 0 0 0 3.42E+07 2.60E+07 - - - 3.4121 0.9999 221125_WJC_METTL3_EV_vs_WT_F05.16269.16269.3 6.41E-09 15/44 K.LKDYAFVHFEDR.G "sp|O43390|HNRPR_HUMAN,tr|B4DT28|B4DT28_HUMAN,tr|A0A6Q8PH31|A0A6Q8PH31_HUMAN,tr|A0A6Q8PH35|A0A6Q8PH35_HUMAN" 4 1538.7518 1.48 67718 16269 3 1538.751589 513.9245 Heterogeneous nuclear ribonucleoprotein R OS=Homo sapiens OX=9606 GN=HNRNPR PE=1 SV=1 5.38 2845.7 - 1.32E+06 - - - -0.1228 - 2.971 0.586 - 275.6 1 2 1 -0.0002 12 0 0 0 3.61E+07 2.44E+07 - - - 8.0915 1 221125_WJC_METTL3_EV_vs_WT_F05.16270.16270.3 7.93E-05 15/56 R.SATNTTLPHMLMSQR[166.11].V "sp|Q8WXI9|P66B_HUMAN,tr|A0A0U1RRM1|A0A0U1RRM1_HUMAN,tr|A0A0U1RR30|A0A0U1RR30_HUMAN" 3 1696.8264 1.89 67719 16270 3 1696.826573 566.6161 Transcriptional repressor p66-beta OS=Homo sapiens OX=9606 GN=GATAD2B PE=1 SV=1 9.49 2845.8 - 1.26E+06 - - - 0.0843 - 2.854 0.463 - 318.2 1 2 0 0.0001 15 0 0 0 1.08E+08 5.70E+07 - - - 6.4385 1 221125_WJC_METTL3_EV_vs_WT_F05.16272.16272.3 6.74E-05 19/72 R.TVVSGSC[160.03]AAHSLLITTEGK[136.11].L sp|Q9P258|RCC2_HUMAN 1 1937.9972 0.63 67721 16272 3 1938.000358 647.0063 Protein RCC2 OS=Homo sapiens OX=9606 GN=RCC2 PE=1 SV=2 6.41 2846 - 752669 - - - 1.6414 - 3.348 0.563 - 236.6 1 2 0 0.0032 19 0 0 0 4.41E+06 7.06E+06 - - - 7.7847 1 221125_WJC_METTL3_EV_vs_WT_F05.16273.16273.3 2.59E-08 13/60 R.TLQEQLENGPNTQLAR.L "sp|Q9P2E9|RRBP1_HUMAN,tr|A0A087WVV2|A0A087WVV2_HUMAN,tr|F8W7S5|F8W7S5_HUMAN" 3 1810.9173 1.64 67722 16273 3 1810.916568 604.6464 Ribosome-binding protein 1 OS=Homo sapiens OX=9606 GN=RRBP1 PE=1 SV=5 4.53 2846.2 - 730036 - - - -0.4263 - 2.881 0.55 - 206.4 1 2 0 -0.0008 16 0 0 0 2.28E+07 1.39E+07 - - - 7.3868 0.9941 221125_WJC_METTL3_EV_vs_WT_F05.16274.16274.3 6.21E-05 Nov-36 R.KQVEEIFNLK[136.11].F "sp|P78347|GTF2I_HUMAN,tr|A0A494C0Q7|A0A494C0Q7_HUMAN,tr|A0A494C1K3|A0A494C1K3_HUMAN" 3 1254.7063 - 67723 16274 3 1254.704481 419.2427 General transcription factor II-I OS=Homo sapiens OX=9606 GN=GTF2I PE=1 SV=2 6.14 2846.3 - 647807 - - - -1.48 - 2.074 0.145 - 192.4 1 2 0 -0.0019 10 0 0 0 - - - - - 2.2865 0.9994 221125_WJC_METTL3_EV_vs_WT_F05.16281.16281.4 3.65E-05 14/66 K.LK[136.11]DYAFVHFEDR[166.11].G "sp|O43390|HNRPR_HUMAN,tr|B4DT28|B4DT28_HUMAN,tr|A0A6Q8PH31|A0A6Q8PH31_HUMAN,tr|A0A6Q8PH35|A0A6Q8PH35_HUMAN" 4 1556.7742 1.34 67728 16281 4 1556.772205 390.2008 Heterogeneous nuclear ribonucleoprotein R OS=Homo sapiens OX=9606 GN=HNRNPR PE=1 SV=1 5.38 2847.2 - 3.01E+06 - - - -1.3123 - 2.698 0.39 - 219.6 1 2 1 -0.002 12 0 0 0 3.44E+07 2.57E+07 - - - 2.9956 1 221125_WJC_METTL3_EV_vs_WT_F05.16282.16282.2 7.92E-09 15/30 L.GGGFSSGGFSGGSFSR.G "sp|P13645|K1C10_HUMAN,tr|A0A1B0GVI3|A0A1B0GVI3_HUMAN" 2 1449.6273 82.39 67729 16282 2 1449.627165 725.8209 "Keratin, type I cytoskeletal 10 OS=Homo sapiens OX=9606 GN=KRT10 PE=1 SV=6" 9.75 2847.3 - 2.88E+06 - - - -0.0973 - 2.748 0.606 - 550.8 1 1 0 -0.0001 16 0 0 0 7.91E+07 9.61E+05 - - - 6.0022 1 221125_WJC_METTL3_EV_vs_WT_F05.16283.16283.3 1.22E-08 17/52 K.AHEILPNLVC[160.03]C[160.03]SAK[136.11].N "sp|P50990|TCPQ_HUMAN,tr|H7C4C8|H7C4C8_HUMAN" 2 1618.8051 0.46 67730 16283 3 1618.802004 540.609 T-complex protein 1 subunit theta OS=Homo sapiens OX=9606 GN=CCT8 PE=1 SV=4 6.77 2847.3 - 2.98E+06 - - - -1.902 - 3.183 0.597 - 534.5 1 2 0 -0.0031 14 0 0 0 4.15E+07 9.08E+07 - - - 8.2721 0.9964 221125_WJC_METTL3_EV_vs_WT_F05.16284.16284.3 0.00277 Dec-44 K.NKLEGLEDALQK.A "sp|P48668|K2C6C_HUMAN,sp|P04259|K2C6B_HUMAN,sp|P02538|K2C6A_HUMAN" 3 1356.7249 203.66 67731 16284 3 1356.722524 453.2489 "Keratin, type II cytoskeletal 6C OS=Homo sapiens OX=9606 GN=KRT6C PE=1 SV=3" 4.68 2847.4 - 1.09E+06 - - - -1.7476 - 2.087 0.288 - 294.7 1 2 1 -0.0024 12 0 0 0 3.25E+07 1.60E+05 - - - 3.7896 0.9999 221125_WJC_METTL3_EV_vs_WT_F05.16286.16286.3 0.00239 Sep-56 R.SNLVDNTNQVEVLQR.D "sp|Q9NUU7|DD19A_HUMAN,sp|Q9UMR2|DD19B_HUMAN,tr|F6QDS0|F6QDS0_HUMAN,tr|H3BMQ5|H3BMQ5_HUMAN,tr|H3BN59|H3BN59_HUMAN,tr|H3BQK0|H3BQK0_HUMAN,tr|H3BTB3|H3BTB3_HUMAN,tr|I3L0H8|I3L0H8_HUMAN" 8 1727.8802 1.11 67733 16286 3 1727.882432 576.9674 ATP-dependent RNA helicase DDX19A OS=Homo sapiens OX=9606 GN=DDX19A PE=1 SV=1 4.37 2847.7 - 873673 - - - 1.2767 - 2.022 0.453 - 123.8 1 2 0 0.0022 15 0 0 0 7.51E+06 6.77E+06 - - - 5.4271 1 221125_WJC_METTL3_EV_vs_WT_F05.16287.16287.2 5.37E-09 15/28 R.SNLVDNTNQVEVLQR[166.11].D "sp|Q9NUU7|DD19A_HUMAN,sp|Q9UMR2|DD19B_HUMAN,tr|F6QDS0|F6QDS0_HUMAN,tr|H3BMQ5|H3BMQ5_HUMAN,tr|H3BN59|H3BN59_HUMAN,tr|H3BQK0|H3BQK0_HUMAN,tr|H3BTB3|H3BTB3_HUMAN,tr|I3L0H8|I3L0H8_HUMAN" 8 1737.8885 1.08 67734 16287 2 1737.888141 869.9515 ATP-dependent RNA helicase DDX19A OS=Homo sapiens OX=9606 GN=DDX19A PE=1 SV=1 4.37 2847.8 - 681672 - - - -0.2043 - 3.12 0.575 - 661.9 1 2 0 -0.0004 15 0 0 0 7.35E+06 6.78E+06 - - - 6.0853 1 221125_WJC_METTL3_EV_vs_WT_F05.16288.16288.3 0.000172 17/72 R.TVVSGSC[160.03]AAHSLLITTEGK.L sp|Q9P258|RCC2_HUMAN 1 1929.983 0.63 67735 16288 3 1929.9853 644.3349 Protein RCC2 OS=Homo sapiens OX=9606 GN=RCC2 PE=1 SV=2 6.41 2847.9 - 604718 - - - 1.2036 - 2.817 0.497 - 190 1 2 0 0.0023 19 0 0 0 4.41E+06 7.06E+06 - - - 6.6249 0.9998 221125_WJC_METTL3_EV_vs_WT_F05.16290.16290.2 7.21E-10 14/28 R.SNLVDNTNQVEVLQR.D "sp|Q9NUU7|DD19A_HUMAN,sp|Q9UMR2|DD19B_HUMAN,tr|F6QDS0|F6QDS0_HUMAN,tr|H3BMQ5|H3BMQ5_HUMAN,tr|H3BN59|H3BN59_HUMAN,tr|H3BQK0|H3BQK0_HUMAN,tr|H3BTB3|H3BTB3_HUMAN,tr|I3L0H8|I3L0H8_HUMAN" 8 1727.8802 1.08 67737 16290 2 1727.883612 864.9474 ATP-dependent RNA helicase DDX19A OS=Homo sapiens OX=9606 GN=DDX19A PE=1 SV=1 4.37 2848.2 - 586298 - - - 1.9596 - 2.712 0.563 - 566.8 1 2 0 0.0034 15 0 0 0 7.35E+06 6.78E+06 - - - 5.6511 1 221125_WJC_METTL3_EV_vs_WT_F05.16291.16291.4 2.96E-08 18/198 R.SDSPVPTAPTSGGPK[136.11]PSTASAVPELATDPELEK[136.11]K[136.11].L "sp|Q86U44|MTA70_HUMAN,tr|B4E349|B4E349_HUMAN,tr|F5H6D8|F5H6D8_HUMAN,tr|B4DTN4|B4DTN4_HUMAN" 4 3384.7363 0.001 67738 16291 4 3384.731692 847.1913 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 4.51 2848.3 - 558887 - - - -1.3499 - 3.152 0.54 - 130.3 1 2 0 -0.0046 34 0 0 0 0.00E+00 1.68E+07 - - - 4.2672 1 221125_WJC_METTL3_EV_vs_WT_F05.16292.16292.2 1.81E-09 15/28 K.DC[160.03]GSVSTVDEFPEAR[166.11].G sp|Q01804|OTUD4_HUMAN 1 1677.718 1.82 67739 16292 2 1677.709361 839.8663 OTU domain-containing protein 4 OS=Homo sapiens OX=9606 GN=OTUD4 PE=1 SV=4 3.92 2848.5 - 558126 - - - -5.1403 - 3.019 0.758 - 905.5 1 2 0 -0.0086 15 0 0 0 1.29E+07 7.09E+06 - - - 7.3534 1 221125_WJC_METTL3_EV_vs_WT_F05.16293.16293.2 8.74E-11 15/30 R.VTELFMDNKNELDQC[160.03]K.S "sp|P52732|KIF11_HUMAN,tr|A0A7I2YQY4|A0A7I2YQY4_HUMAN,tr|A0A7I2V3A9|A0A7I2V3A9_HUMAN,tr|A0A7I2V3V3|A0A7I2V3V3_HUMAN" 4 1982.9078 6.3 67740 16293 2 1982.906305 992.4612 Kinesin-like protein KIF11 OS=Homo sapiens OX=9606 GN=KIF11 PE=1 SV=2 4.32 2848.6 - 552252 - - - -0.7353 - 3.35 0.695 - 599 1 2 1 -0.0015 16 0 0 0 5.17E+06 8.20E+05 - - - 7.1461 1 221125_WJC_METTL3_EV_vs_WT_F05.16295.16295.3 5.12E-15 20/56 K.HLEINPDHPIVETLR.Q sp|P08238|HS90B_HUMAN 1 1781.9424 1.1 67741 16295 3 1781.943413 594.9881 Heat shock protein HSP 90-beta OS=Homo sapiens OX=9606 GN=HSP90AB1 PE=1 SV=4 5.27 2848.8 - 1.32E+07 - - - 0.55 - 4.317 0.689 - 513.6 1 2 0 0.001 15 0 0 0 2.12E+08 1.92E+08 - - - 10.0378 1 221125_WJC_METTL3_EV_vs_WT_F05.16296.16296.3 9.15E-05 13/56 R.SATNTTLPHMLMSQR.V "sp|Q8WXI9|P66B_HUMAN,tr|A0A0U1RRM1|A0A0U1RRM1_HUMAN,tr|A0A0U1RR30|A0A0U1RR30_HUMAN" 3 1686.8182 1.52 67742 16296 3 1686.8166 563.28 Transcriptional repressor p66-beta OS=Homo sapiens OX=9606 GN=GATAD2B PE=1 SV=1 9.49 2848.9 - 1.25E+06 - - - -0.9248 - 2.718 0.461 - 252 1 2 0 -0.0016 15 0 0 0 8.45E+07 5.57E+07 - - - 6.2884 1 221125_WJC_METTL3_EV_vs_WT_F05.16297.16297.2 6.79E-15 17/28 K.DC[160.03]GSVSTVDEFPEAR.G sp|Q01804|OTUD4_HUMAN 1 1667.7097 1.82 67743 16297 2 1667.707164 834.8621 OTU domain-containing protein 4 OS=Homo sapiens OX=9606 GN=OTUD4 PE=1 SV=4 3.92 2849 - 1.00E+06 - - - -1.5296 - 3.213 0.612 - 1107.9 1 2 0 -0.0026 15 0 0 0 1.29E+07 7.09E+06 - - - 6.4301 1 221125_WJC_METTL3_EV_vs_WT_F05.16299.16299.2 4.46E-05 17/30 R.TLQEQLENGPNTQLAR.L "sp|Q9P2E9|RRBP1_HUMAN,tr|A0A087WVV2|A0A087WVV2_HUMAN,tr|F8W7S5|F8W7S5_HUMAN" 3 1810.9173 1.78 67745 16299 2 1810.917931 906.4659 Ribosome-binding protein 1 OS=Homo sapiens OX=9606 GN=RRBP1 PE=1 SV=5 4.53 2849.3 - 763709 - - - 0.3264 - 3.701 0.546 - 958 1 2 0 0.0006 16 0 0 0 1.19E+07 6.71E+06 - - - 6.2908 0.9913 221125_WJC_METTL3_EV_vs_WT_F05.16300.16300.3 1.61E-07 15/52 L.ESQTYEVFEKDPIK.Y "sp|O14744|ANM5_HUMAN,tr|H0YJ77|H0YJ77_HUMAN,tr|G3V2L6|G3V2L6_HUMAN,tr|G3V5T6|G3V5T6_HUMAN,tr|H0YJX6|H0YJX6_HUMAN" 5 1711.8305 6.25 67746 16300 3 1711.829281 571.6174 Protein arginine N-methyltransferase 5 OS=Homo sapiens OX=9606 GN=PRMT5 PE=1 SV=4 4.41 2849.4 - 714400 - - - -0.7016 - 2.661 0.544 - 372.8 1 1 1 -0.0012 14 0 0 0 1.30E+07 2.08E+06 - - - 7.2057 1 221125_WJC_METTL3_EV_vs_WT_F05.16301.16301.3 4.51E-10 20/52 R.NLHHELELGVVMGK.R sp|Q6P587|FAHD1_HUMAN 1 1574.8239 0.95 67747 16301 3 1574.822485 525.9486 "Acylpyruvase FAHD1, mitochondrial OS=Homo sapiens OX=9606 GN=FAHD1 PE=1 SV=2" 6 2849.5 - 596625 - - - -0.8966 - 3.976 0.565 - 890.6 1 2 0 -0.0014 14 0 0 0 7.98E+06 8.39E+06 - - - 8.5069 1 221125_WJC_METTL3_EV_vs_WT_F05.16302.16302.3 2.36E-07 21/80 K.MASAPASYGSTTTKPMGLLSR.V "sp|Q8WVM8|SCFD1_HUMAN,tr|A0A7I2V4U2|A0A7I2V4U2_HUMAN,tr|A0A7I2V4B8|A0A7I2V4B8_HUMAN,tr|A0A7I2V5Z4|A0A7I2V5Z4_HUMAN,tr|B7Z5N7|B7Z5N7_HUMAN,tr|A0A7I2V5I2|A0A7I2V5I2_HUMAN,tr|A0A7I2V2U5|A0A7I2V2U5_HUMAN,tr|A0A7I2V448|A0A7I2V448_HUMAN,tr|A0A7I2V320|A0A7I2V320_HUMAN,tr|A0A7I2V3G4|A0A7I2V3G4_HUMAN,tr|A0A7I2V3B4|A0A7I2V3B4_HUMAN,tr|G3V2M8|G3V2M8_HUMAN,tr|A0A7I2V4R0|A0A7I2V4R0_HUMAN" 13 2126.05 1.15 67748 16302 3 2126.047172 709.6906 Sec1 family domain-containing protein 1 OS=Homo sapiens OX=9606 GN=SCFD1 PE=1 SV=4 9.99 2849.7 - 536741 - - - -1.3353 - 3.933 0.62 - 489.6 1 2 0 -0.0028 21 0 0 0 5.09E+06 4.43E+06 - - - 8.7347 0.9999 221125_WJC_METTL3_EV_vs_WT_F05.16306.16306.3 1.20E-06 15/52 K.QMADTGK[136.11]LNTLLQR[166.11].A "sp|Q00839|HNRPU_HUMAN,tr|A0A1W2PQL0|A0A1W2PQL0_HUMAN,tr|A0A1W2PPE9|A0A1W2PPE9_HUMAN,tr|A0A1W2PPL4|A0A1W2PPL4_HUMAN,tr|A0A1W2PQ74|A0A1W2PQ74_HUMAN,tr|Q5RI18|Q5RI18_HUMAN,tr|A0A1W2PP35|A0A1W2PP35_HUMAN,tr|A0A1W2PPS1|A0A1W2PPS1_HUMAN,tr|A0A1W2PRZ7|A0A1W2PRZ7_HUMAN,tr|A0A1W2PPH7|A0A1W2PPH7_HUMAN,tr|A0A1W2PQD4|A0A1W2PQD4_HUMAN,tr|A0A1W2PP34|A0A1W2PP34_HUMAN,tr|A0A1X7SBS1|A0A1X7SBS1_HUMAN" 13 1605.8627 0.83 67751 16306 3 1605.862213 536.2949 Heterogeneous nuclear ribonucleoprotein U OS=Homo sapiens OX=9606 GN=HNRNPU PE=1 SV=6 8.75 2850.1 - 1.46E+06 - - - -0.3319 - 2.523 0.591 - 325.7 1 2 1 -0.0005 14 0 0 0 7.30E+07 8.79E+07 - - - 7.5883 1 221125_WJC_METTL3_EV_vs_WT_F05.16309.16309.3 1.78E-05 18/52 K.AHEILPNLVC[160.03]C[160.03]SAK.N "sp|P50990|TCPQ_HUMAN,tr|H7C4C8|H7C4C8_HUMAN" 2 1610.7909 0.45 67753 16309 3 1610.79142 537.9376 T-complex protein 1 subunit theta OS=Homo sapiens OX=9606 GN=CCT8 PE=1 SV=4 6.77 2850.4 - 2.60E+06 - - - 0.3334 - 3.361 0.614 - 615.9 1 2 0 0.0005 14 0 0 0 4.12E+07 9.08E+07 - - - 8.6069 0.9959 221125_WJC_METTL3_EV_vs_WT_F05.16310.16310.3 0.0358 Dec-44 R.LIDLHSPSEIVK[136.11].Q "sp|P60866|RS20_HUMAN,tr|A0A7P0S5H5|A0A7P0S5H5_HUMAN,tr|G3XAN0|G3XAN0_HUMAN" 3 1357.7697 1.62 67754 16310 3 1357.770357 453.5972 40S ribosomal protein S20 OS=Homo sapiens OX=9606 GN=RPS20 PE=1 SV=1 5.32 2850.5 - 1.12E+06 - - - 0.5082 - 2.068 0.162 - 207.4 1 2 0 0.0007 12 0 0 0 2.32E+07 1.43E+07 - - - 2.3599 1 221125_WJC_METTL3_EV_vs_WT_F05.16311.16311.3 5.01E-05 15/56 R.SNLVDNTNQVEVLQR[166.11].D "sp|Q9NUU7|DD19A_HUMAN,sp|Q9UMR2|DD19B_HUMAN,tr|F6QDS0|F6QDS0_HUMAN,tr|H3BMQ5|H3BMQ5_HUMAN,tr|H3BN59|H3BN59_HUMAN,tr|H3BQK0|H3BQK0_HUMAN,tr|H3BTB3|H3BTB3_HUMAN,tr|I3L0H8|I3L0H8_HUMAN" 8 1737.8885 1.11 67755 16311 3 1737.889643 580.3034 ATP-dependent RNA helicase DDX19A OS=Homo sapiens OX=9606 GN=DDX19A PE=1 SV=1 4.37 2850.6 - 944341 - - - 0.66 - 3.066 0.534 - 347.7 1 2 0 0.0011 15 0 0 0 7.51E+06 6.77E+06 - - - 7.4167 1 221125_WJC_METTL3_EV_vs_WT_F05.16312.16312.3 7.09E-09 18/44 K.TPELNLDQFHDK.T "sp|P27824|CALX_HUMAN,tr|A0A7P0T937|A0A7P0T937_HUMAN,tr|A0A7P0T840|A0A7P0T840_HUMAN,tr|D6RFL1|D6RFL1_HUMAN,tr|A0A7P0Z4H2|A0A7P0Z4H2_HUMAN,tr|A0A7P0TB65|A0A7P0TB65_HUMAN,tr|A0A7P0TAE9|A0A7P0TAE9_HUMAN,tr|D6RGY2|D6RGY2_HUMAN,tr|A0A7P0T8G1|A0A7P0T8G1_HUMAN,tr|A0A7P0Z4D6|A0A7P0Z4D6_HUMAN,tr|A0A7P0Z484|A0A7P0Z484_HUMAN,tr|A0A7P0TAR9|A0A7P0TAR9_HUMAN,tr|A0A7P0T9L0|A0A7P0T9L0_HUMAN" 13 1455.6994 1.37 67756 16312 3 1455.699045 486.2404 Calnexin OS=Homo sapiens OX=9606 GN=CANX PE=1 SV=2 4.53 2850.7 - 750043 - - - -0.2494 - 3.384 0.544 - 674.5 1 2 0 -0.0004 12 0 0 0 2.41E+08 1.75E+08 - - - 7.984 1 221125_WJC_METTL3_EV_vs_WT_F05.16313.16313.2 6.64E-05 14/30 R.TLQEQLENGPNTQLAR[166.11].L "sp|Q9P2E9|RRBP1_HUMAN,tr|A0A087WVV2|A0A087WVV2_HUMAN,tr|F8W7S5|F8W7S5_HUMAN" 3 1820.9256 1.78 67757 16313 2 1820.922365 911.4701 Ribosome-binding protein 1 OS=Homo sapiens OX=9606 GN=RRBP1 PE=1 SV=5 4.53 2850.8 - 704520 - - - -1.7821 - 3.49 0.555 - 725 1 2 0 -0.0032 16 0 0 0 1.19E+07 6.71E+06 - - - 6.2122 1 221125_WJC_METTL3_EV_vs_WT_F05.16314.16314.3 1.44E-10 34/88 K.LAQQQAAAAAAAAAAASQQGSAK.N "sp|Q9BZK7|TBL1R_HUMAN,tr|A0A1B0GUU2|A0A1B0GUU2_HUMAN,tr|C9IYU9|C9IYU9_HUMAN,tr|C9JCK0|C9JCK0_HUMAN,tr|A0A0D9SF63|A0A0D9SF63_HUMAN,tr|C9JBN1|C9JBN1_HUMAN,tr|C9JLJ1|C9JLJ1_HUMAN,tr|A0A0D9SF25|A0A0D9SF25_HUMAN" 8 2054.0505 1.85 67758 16314 3 2054.059801 685.6908 F-box-like\WD repeat-containing protein TBL1XR1 OS=Homo sapiens OX=9606 GN=TBL1XR1 PE=1 SV=1 8.75 2851 - 593775 - - - 4.5379 - 5.612 0.672 - 1682.1 1 2 0 0.0093 23 0 0 0 2.14E+07 1.16E+07 - - - 10.0761 0.9999 221125_WJC_METTL3_EV_vs_WT_F05.16315.16315.3 6.97E-07 14/40 K.EAELDKYLEC[160.03]R.V sp|P35813|PPM1A_HUMAN 1 1424.6606 1.78 67759 16315 3 1424.661231 475.8941 Protein phosphatase 1A OS=Homo sapiens OX=9606 GN=PPM1A PE=1 SV=1 4.41 2851.1 - 591534 - - - 0.457 - 2.312 0.533 - 366.9 1 2 1 0.0007 11 0 0 0 5.62E+06 3.15E+06 - - - 6.8632 0.9999 221125_WJC_METTL3_EV_vs_WT_F05.16316.16316.3 1.52E-10 17/64 K.TKVEPYSLTAQQSSLIR.E "sp|Q96T88|UHRF1_HUMAN,tr|A0A087WWG9|A0A087WWG9_HUMAN,tr|A0A087WTW0|A0A087WTW0_HUMAN,tr|A0A087WVR3|A0A087WVR3_HUMAN" 4 1920.0316 2.17 67760 16316 3 1920.036829 641.0178 E3 ubiquitin-protein ligase UHRF1 OS=Homo sapiens OX=9606 GN=UHRF1 PE=1 SV=1 8.26 2851.2 - 576469 - - - 2.7015 - 3.648 0.584 - 332.1 1 2 1 0.0052 17 0 0 0 4.40E+06 2.03E+06 - - - 8.3191 1 221125_WJC_METTL3_EV_vs_WT_F05.16317.16317.3 4.24E-05 21/44 K.TPELNLDQFHDK[136.11].T "sp|P27824|CALX_HUMAN,tr|A0A7P0T937|A0A7P0T937_HUMAN,tr|A0A7P0T840|A0A7P0T840_HUMAN,tr|D6RFL1|D6RFL1_HUMAN,tr|A0A7P0Z4H2|A0A7P0Z4H2_HUMAN,tr|A0A7P0TB65|A0A7P0TB65_HUMAN,tr|A0A7P0TAE9|A0A7P0TAE9_HUMAN,tr|D6RGY2|D6RGY2_HUMAN,tr|A0A7P0T8G1|A0A7P0T8G1_HUMAN,tr|A0A7P0Z4D6|A0A7P0Z4D6_HUMAN,tr|A0A7P0Z484|A0A7P0Z484_HUMAN,tr|A0A7P0TAR9|A0A7P0TAR9_HUMAN,tr|A0A7P0T9L0|A0A7P0T9L0_HUMAN" 13 1463.7136 1.38 67761 16317 3 1463.714365 488.9118 Calnexin OS=Homo sapiens OX=9606 GN=CANX PE=1 SV=2 4.53 2851.3 - 561850 - - - 0.5172 - 3.632 0.459 - 1019.6 1 2 0 0.0008 12 0 0 0 2.42E+08 1.76E+08 - - - 7.2323 0.9997 221125_WJC_METTL3_EV_vs_WT_F05.16318.16318.3 0.00125 Dec-60 R.NFILDQTNVSAAAQRR.K "sp|Q00839|HNRPU_HUMAN,tr|A0A1W2PQL0|A0A1W2PQL0_HUMAN,tr|A0A1W2PPL4|A0A1W2PPL4_HUMAN,tr|A0A1W2PQ74|A0A1W2PQ74_HUMAN,tr|Q5RI18|Q5RI18_HUMAN,tr|A0A1W2PP35|A0A1W2PP35_HUMAN,tr|A0A1W2PPS1|A0A1W2PPS1_HUMAN,tr|A0A1W2PRZ7|A0A1W2PRZ7_HUMAN,tr|A0A1W2PPH7|A0A1W2PPH7_HUMAN,tr|A0A1W2PQD4|A0A1W2PQD4_HUMAN,tr|A0A1W2PP34|A0A1W2PP34_HUMAN,tr|A0A1X7SBS1|A0A1X7SBS1_HUMAN" 12 1802.9387 0.83 67762 16318 3 1802.938868 601.9869 Heterogeneous nuclear ribonucleoprotein U OS=Homo sapiens OX=9606 GN=HNRNPU PE=1 SV=6 9.6 2851.4 - 492782 - - - 0.0688 - 2.005 0.363 - 165.4 1 2 0 0.0001 16 0 0 0 7.07E+06 8.54E+06 - - - 4.372 0.9994 221125_WJC_METTL3_EV_vs_WT_F05.16319.16319.3 0.000694 13/40 K.EAELDK[136.11]YLEC[160.03]R[166.11].V sp|P35813|PPM1A_HUMAN 1 1442.6831 2.14 67763 16319 3 1442.68355 481.9016 Protein phosphatase 1A OS=Homo sapiens OX=9606 GN=PPM1A PE=1 SV=1 4.41 2851.6 - 456406 - - - 0.3466 - 2.203 0.373 - 285.9 1 2 1 0.0005 11 0 0 0 6.65E+06 3.11E+06 - - - 4.9422 0.9933 221125_WJC_METTL3_EV_vs_WT_F05.16321.16321.2 3.92E-09 14/38 R.QGGSVAQAPAGTSFVAPVGH.S "sp|Q8IWZ3|ANKH1_HUMAN,tr|A0A0A0MQZ8|A0A0A0MQZ8_HUMAN,tr|H0Y472|H0Y472_HUMAN,tr|H0Y7Y3|H0Y7Y3_HUMAN,tr|H0Y4P6|H0Y4P6_HUMAN,tr|H7C0V5|H7C0V5_HUMAN,tr|H0Y785|H0Y785_HUMAN,tr|H7C2E1|H7C2E1_HUMAN" 8 1836.9119 - 67765 16321 2 1836.912797 919.4632 Ankyrin repeat and KH domain-containing protein 1 OS=Homo sapiens OX=9606 GN=ANKHD1 PE=1 SV=1 6.74 2851.8 - 362906 - - - 0.5096 - 2.475 0.526 - 398.8 1 1 0 0.0009 20 0 0 0 - - - - - 5.1538 1 221125_WJC_METTL3_EV_vs_WT_F05.16326.16326.3 1.41E-10 18/60 R.GIYAYGFEKPSAIQQR.A "sp|Q14240|IF4A2_HUMAN,sp|P38919|IF4A3_HUMAN,sp|P60842|IF4A1_HUMAN,tr|J3KTB5|J3KTB5_HUMAN,tr|J3KT04|J3KT04_HUMAN,tr|J3KS93|J3KS93_HUMAN,tr|E7EMV8|E7EMV8_HUMAN,tr|J3KT12|J3KT12_HUMAN,tr|J3QKZ9|J3QKZ9_HUMAN,tr|J3QS69|J3QS69_HUMAN,tr|I3L3H2|I3L3H2_HUMAN,tr|J3QL43|J3QL43_HUMAN,tr|F8WE11|F8WE11_HUMAN,tr|E7EQG2|E7EQG2_HUMAN,tr|J3KS25|J3KS25_HUMAN,tr|E9PBH4|E9PBH4_HUMAN,tr|J3QLN6|J3QLN6_HUMAN,tr|J3QQP0|J3QQP0_HUMAN,tr|J3QR64|J3QR64_HUMAN,tr|J3KSN7|J3KSN7_HUMAN" 20 1826.9315 1.46 67768 16326 3 1826.935405 609.9845 Eukaryotic initiation factor 4A-II OS=Homo sapiens OX=9606 GN=EIF4A2 PE=1 SV=2 8.5 2852.5 - 2.70E+06 - - - 2.1189 - 3.068 0.656 - 322.7 1 2 0 0.0039 16 0 0 0 2.48E+07 1.70E+07 - - - 8.7291 0.9999 221125_WJC_METTL3_EV_vs_WT_F05.16327.16327.3 2.88E-06 19/40 K.FAAQELIEVK[136.11]R[166.11].G "sp|Q86U44|MTA70_HUMAN,tr|F5H6D8|F5H6D8_HUMAN,tr|H0YFV6|H0YFV6_HUMAN,tr|B4DTN4|B4DTN4_HUMAN" 4 1320.7521 0 67769 16327 3 1320.752855 441.258 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 6.14 2852.5 - 2.79E+06 - - - 0.605 - 2.887 0.347 - 354 1 2 0 0.0008 11 0 0 0 7.63E+05 2.58E+08 - - - 5.4204 1 221125_WJC_METTL3_EV_vs_WT_F05.16328.16328.3 1.04E-07 18/72 K.QITSYGETC[160.03]PGLEQYAIK[136.11]K[136.11].F sp|P50990|TCPQ_HUMAN 1 2201.1009 0.45 67770 16328 3 2201.102074 734.7076 T-complex protein 1 subunit theta OS=Homo sapiens OX=9606 GN=CCT8 PE=1 SV=4 6.13 2852.6 - 3.47E+06 - - - 0.5243 - 3.166 0.586 - 208.4 1 2 0 0.0012 19 0 0 0 3.91E+07 8.70E+07 - - - 7.9044 1 221125_WJC_METTL3_EV_vs_WT_F05.16329.16329.3 6.02E-06 25/72 M.PAGPVQAVPPPPPVPTEPK.Q "sp|Q15459|SF3A1_HUMAN,tr|F8WB66|F8WB66_HUMAN,tr|F8WC79|F8WC79_HUMAN" 3 1874.0302 1.25 67771 16329 3 1874.033458 625.684 Splicing factor 3A subunit 1 OS=Homo sapiens OX=9606 GN=SF3A1 PE=1 SV=1 6.43 2852.7 - 2.47E+06 - - - 1.7465 - 4.814 0.563 - 1274.9 1 2 0 0.0033 19 0 0 0 2.50E+07 2.00E+07 - - - 8.6769 1 221125_WJC_METTL3_EV_vs_WT_F05.16331.16331.3 0.00362 13/44 R.LIDLHSPSEIVK.Q "sp|P60866|RS20_HUMAN,tr|A0A7P0S5H5|A0A7P0S5H5_HUMAN,tr|G3XAN0|G3XAN0_HUMAN" 3 1349.7555 1.62 67773 16331 3 1349.756242 450.9258 40S ribosomal protein S20 OS=Homo sapiens OX=9606 GN=RPS20 PE=1 SV=1 5.32 2852.8 - 1.97E+06 - - - 0.5742 - 2.607 0.425 - 203.7 1 2 0 0.0008 12 0 0 0 2.32E+07 1.43E+07 - - - 5.9341 1 221125_WJC_METTL3_EV_vs_WT_F05.16332.16332.3 5.98E-09 19/60 R.GIYAYGFEK[136.11]PSAIQQR[166.11].A "sp|Q14240|IF4A2_HUMAN,sp|P38919|IF4A3_HUMAN,sp|P60842|IF4A1_HUMAN,tr|J3KTB5|J3KTB5_HUMAN,tr|J3KT04|J3KT04_HUMAN,tr|J3KS93|J3KS93_HUMAN,tr|E7EMV8|E7EMV8_HUMAN,tr|J3KT12|J3KT12_HUMAN,tr|J3QKZ9|J3QKZ9_HUMAN,tr|J3QS69|J3QS69_HUMAN,tr|I3L3H2|I3L3H2_HUMAN,tr|J3QL43|J3QL43_HUMAN,tr|F8WE11|F8WE11_HUMAN,tr|E7EQG2|E7EQG2_HUMAN,tr|J3KS25|J3KS25_HUMAN,tr|E9PBH4|E9PBH4_HUMAN,tr|J3QLN6|J3QLN6_HUMAN,tr|J3QQP0|J3QQP0_HUMAN,tr|J3QR64|J3QR64_HUMAN,tr|J3KSN7|J3KSN7_HUMAN" 20 1844.954 1.47 67774 16332 3 1844.957129 615.9919 Eukaryotic initiation factor 4A-II OS=Homo sapiens OX=9606 GN=EIF4A2 PE=1 SV=2 8.5 2852.8 - 1.92E+06 - - - 1.6938 - 3.577 0.637 - 365.5 1 2 0 0.0031 16 0 0 0 2.50E+07 1.70E+07 - - - 8.9113 1 221125_WJC_METTL3_EV_vs_WT_F05.16333.16333.3 1.85E-06 20/72 M.PAGPVQAVPPPPPVPTEPK[136.11].Q "sp|Q15459|SF3A1_HUMAN,tr|F8WB66|F8WB66_HUMAN,tr|F8WC79|F8WC79_HUMAN" 3 1882.0444 1.27 67775 16333 3 1882.047301 628.3554 Splicing factor 3A subunit 1 OS=Homo sapiens OX=9606 GN=SF3A1 PE=1 SV=1 6.43 2852.9 - 1.78E+06 - - - 1.5494 - 4.292 0.564 - 706 1 2 0 0.0029 19 0 0 0 2.43E+07 1.91E+07 - - - 8.4062 1 221125_WJC_METTL3_EV_vs_WT_F05.16334.16334.3 3.36E-09 14/56 R.GPSLNPVLDYDHGSR.S "sp|P43243|MATR3_HUMAN,tr|A8MXP9|A8MXP9_HUMAN,tr|D6R991|D6R991_HUMAN,tr|A0A0R4J2E8|A0A0R4J2E8_HUMAN,tr|D6REM6|D6REM6_HUMAN" 5 1625.7798 1.1 67776 16334 3 1625.779328 542.9339 Matrin-3 OS=Homo sapiens OX=9606 GN=MATR3 PE=1 SV=2 5.21 2853 - 1.31E+06 - - - -0.2805 - 3.027 0.602 - 344.2 1 2 0 -0.0005 15 0 0 0 1.75E+07 1.59E+07 - - - 8.1416 1 221125_WJC_METTL3_EV_vs_WT_F05.16336.16336.3 4.35E-08 20/72 K.QITSYGETC[160.03]PGLEQYAIKK.F sp|P50990|TCPQ_HUMAN 1 2185.0725 0.45 67778 16336 3 2185.074586 729.3648 T-complex protein 1 subunit theta OS=Homo sapiens OX=9606 GN=CCT8 PE=1 SV=4 6.13 2853.2 - 1.13E+06 - - - 0.9455 - 3.47 0.566 - 349.7 1 2 0 0.0021 19 0 0 0 3.92E+07 8.75E+07 - - - 7.9064 1 221125_WJC_METTL3_EV_vs_WT_F05.16338.16338.3 3.36E-05 18/76 R.QVEPLDPPAGSAPGEHVFVK.G "sp|P54577|SYYC_HUMAN,tr|A0A6Q8PFX2|A0A6Q8PFX2_HUMAN" 2 2073.0531 0.9 67780 16338 3 2073.056522 692.025 "Tyrosine--tRNA ligase, cytoplasmic OS=Homo sapiens OX=9606 GN=YARS1 PE=1 SV=4" 4.65 2853.4 - 923409 - - - 1.6483 - 3.31 0.48 - 320.8 1 2 0 0.0034 20 0 0 0 4.72E+07 5.25E+07 - - - 6.7944 0.9846 221125_WJC_METTL3_EV_vs_WT_F05.16341.16341.3 0.000133 Nov-48 K.AK[136.11]IELLGSYDPQK[136.11].Q sp|P24666|PPAC_HUMAN 1 1476.8159 1.04 67783 16341 3 1476.818899 493.2792 Low molecular weight phosphotyrosine protein phosphatase OS=Homo sapiens OX=9606 GN=ACP1 PE=1 SV=3 6.11 2853.8 - 742838 - - - 2.0341 - 1.926 0.235 - 160.6 1 2 1 0.003 13 0 0 0 6.34E+07 6.12E+07 - - - 2.9363 0.9993 221125_WJC_METTL3_EV_vs_WT_F05.16343.16343.3 0.00175 Oct-32 K.LVKEEVFWR.N sp|Q96A49|SYAP1_HUMAN 1 1204.6604 1.1 67785 16343 3 1204.661304 402.5608 Synapse-associated protein 1 OS=Homo sapiens OX=9606 GN=SYAP1 PE=1 SV=1 6.14 2854 - 598432 - - - 0.7139 - 2.223 0.351 - 156 1 2 1 0.0009 9 0 0 0 3.97E+06 3.60E+06 - - - 4.8607 0.9996 221125_WJC_METTL3_EV_vs_WT_F05.16345.16345.3 0.000425 Oct-32 K.LVK[136.11]EEVFWR[166.11].N sp|Q96A49|SYAP1_HUMAN 1 1222.6829 1.1 67787 16345 3 1222.684142 408.5682 Synapse-associated protein 1 OS=Homo sapiens OX=9606 GN=SYAP1 PE=1 SV=1 6.14 2854.3 - 489651 - - - 1.0043 - 2.175 0.411 - 176.9 1 2 1 0.0012 9 0 0 0 3.97E+06 3.60E+06 - - - 5.4637 1 221125_WJC_METTL3_EV_vs_WT_F05.16347.16347.2 6.17E-09 13/26 R.EEFPTLQAAGDQDK[136.11].A sp|P48634|PRC2A_HUMAN 1 1555.7246 1.98 67788 16347 2 1555.723932 778.8696 Protein PRRC2A OS=Homo sapiens OX=9606 GN=PRRC2A PE=1 SV=3 3.92 2854.5 - 647709 - - - -0.4082 - 2.679 0.624 - 603.7 1 2 0 -0.0006 14 0 0 0 1.49E+07 7.52E+06 - - - 6.1226 0.9996 221125_WJC_METTL3_EV_vs_WT_F05.16348.16348.2 0.00247 13/26 K.AHEILPNLVC[160.03]C[160.03]SAK[136.11].N "sp|P50990|TCPQ_HUMAN,tr|H7C4C8|H7C4C8_HUMAN" 2 1618.8051 0.24 67789 16348 2 1618.810121 810.4098 T-complex protein 1 subunit theta OS=Homo sapiens OX=9606 GN=CCT8 PE=1 SV=4 6.77 2854.6 - 417546 - - - 3.1122 - 2.596 0.558 - 550.3 1 2 0 0.005 14 0 0 0 1.15E+06 4.87E+06 - - - 5.5548 1 221125_WJC_METTL3_EV_vs_WT_F05.16351.16351.2 1.40E-07 26-Nov R.EEFPTLQAAGDQDK.A sp|P48634|PRC2A_HUMAN 1 1547.7104 1.65 67792 16351 2 1547.70816 774.8625 Protein PRRC2A OS=Homo sapiens OX=9606 GN=PRRC2A PE=1 SV=3 3.92 2854.8 - 773042 - - - -1.426 - 2.365 0.615 - 376.6 1 2 0 -0.0022 14 0 0 0 1.24E+07 7.52E+06 - - - 5.7428 0.9998 221125_WJC_METTL3_EV_vs_WT_F05.16352.16352.3 0.00115 Dec-36 K.GNK[136.11]PWISLPR[166.11].G "sp|P62701|RS4X_HUMAN,sp|P22090|RS4Y1_HUMAN,sp|Q8TD47|RS4Y2_HUMAN,tr|C9JEH7|C9JEH7_HUMAN" 4 1184.6785 0.97 67793 16352 3 1184.679688 395.9001 "40S ribosomal protein S4, X isoform OS=Homo sapiens OX=9606 GN=RPS4X PE=1 SV=2" 11 2855 - 622392 - - - 1.0053 - 2.229 0.355 - 158.4 1 2 0 0.0012 10 0 0 0 7.84E+07 8.09E+07 - - - 4.8385 1 221125_WJC_METTL3_EV_vs_WT_F05.16354.16354.3 3.33E-09 21/76 R.HLLEGQNASVLAYGPTGAGK[136.11].T "sp|Q14807|KIF22_HUMAN,tr|H3BRB3|H3BRB3_HUMAN,tr|H3BTH5|H3BTH5_HUMAN" 3 1990.0363 1.21 67795 16354 3 1990.037899 664.3527 Kinesin-like protein KIF22 OS=Homo sapiens OX=9606 GN=KIF22 PE=1 SV=5 6.75 2855.2 - 344154 - - - 0.7834 - 3.825 0.495 - 718.9 1 2 0 0.0016 20 0 0 0 4.80E+06 3.99E+06 - - - 7.313 0.9997 221125_WJC_METTL3_EV_vs_WT_F05.16355.16355.3 0.000682 Oct-48 R.VDQLSQQLEDLK[136.11]K[136.11].G "sp|Q96KQ4|ASPP1_HUMAN,tr|A0A3B3ISJ2|A0A3B3ISJ2_HUMAN" 2 1558.8537 2.68 67796 16355 3 1558.853243 520.6252 Apoptosis-stimulating of p53 protein 1 OS=Homo sapiens OX=9606 GN=PPP1R13B PE=1 SV=3 4.56 2855.4 - 415058 - - - -0.3169 - 1.77 0.382 - 78.2 1 2 0 -0.0005 13 0 0 0 7.53E+06 2.81E+06 - - - 4.3469 0.9999 221125_WJC_METTL3_EV_vs_WT_F05.16356.16356.2 0.00114 13/36 M.PAGPVQAVPPPPPVPTEPK.Q "sp|Q15459|SF3A1_HUMAN,tr|F8WB66|F8WB66_HUMAN,tr|F8WC79|F8WC79_HUMAN" 3 1874.0302 1.31 67797 16356 2 1874.02932 938.0224 Splicing factor 3A subunit 1 OS=Homo sapiens OX=9606 GN=SF3A1 PE=1 SV=1 6.43 2855.5 - 268762 - - - -0.4616 - 2.79 0.521 - 316.1 1 2 0 -0.0009 19 0 0 0 4.59E+06 3.50E+06 - - - 5.4114 1 221125_WJC_METTL3_EV_vs_WT_F05.16358.16358.2 8.16E-10 14/36 M.PAGPVQAVPPPPPVPTEPK[136.11].Q "sp|Q15459|SF3A1_HUMAN,tr|F8WB66|F8WB66_HUMAN,tr|F8WC79|F8WC79_HUMAN" 3 1882.0444 1.31 67799 16358 2 1882.046637 942.0295 Splicing factor 3A subunit 1 OS=Homo sapiens OX=9606 GN=SF3A1 PE=1 SV=1 6.43 2855.7 - 243528 - - - 1.1966 - 2.954 0.651 - 457.7 1 2 0 0.0023 19 0 0 0 4.59E+06 3.50E+06 - - - 6.5116 0.9998 221125_WJC_METTL3_EV_vs_WT_F05.16359.16359.2 1.88E-07 30-Dec K.TVQSNSPISALAPTGK.E sp|O95292|VAPB_HUMAN 1 1569.8362 1.82 67800 16359 2 1569.832761 785.9254 Vesicle-associated membrane protein-associated protein B\C OS=Homo sapiens OX=9606 GN=VAPB PE=1 SV=3 8.41 2855.9 - 189973 - - - -2.2136 - 2.362 0.601 - 364 1 2 0 -0.0035 16 0 0 0 6.57E+06 3.61E+06 - - - 5.592 0.9998 221125_WJC_METTL3_EV_vs_WT_F05.16360.16360.2 1.53E-06 30-Aug K.ASLNGADIYSGC[160.03]C[160.03]TLK.L "sp|P14866|HNRPL_HUMAN,tr|B4DVF8|B4DVF8_HUMAN,tr|M0R1W6|M0R1W6_HUMAN,tr|A0A3B3ITJ4|A0A3B3ITJ4_HUMAN,tr|M0QXS5|M0QXS5_HUMAN" 5 1728.7811 -1 67801 16360 2 1728.779043 865.3978 Heterogeneous nuclear ribonucleoprotein L OS=Homo sapiens OX=9606 GN=HNRNPL PE=1 SV=2 5.86 2856 - 165702 - - - -1.1933 - 1.83 0.572 - 95.3 1 2 0 -0.0021 16 0 0 0 0.00E+00 0.00E+00 - - - 4.7509 1 221125_WJC_METTL3_EV_vs_WT_F05.16366.16366.3 2.57E-08 19/76 R.QVEPLDPPAGSAPGEHVFVK[136.11].G "sp|P54577|SYYC_HUMAN,tr|A0A6Q8PFX2|A0A6Q8PFX2_HUMAN" 2 2081.0673 0.9 67805 16366 3 2081.06836 694.6964 "Tyrosine--tRNA ligase, cytoplasmic OS=Homo sapiens OX=9606 GN=YARS1 PE=1 SV=4" 4.65 2856.7 - 1.34E+06 - - - 0.507 - 3.345 0.462 - 367.5 1 2 0 0.0011 20 0 0 0 4.60E+07 5.12E+07 - - - 6.6199 0.9998 221125_WJC_METTL3_EV_vs_WT_F05.16367.16367.3 0.00155 Dec-36 K.GNKPWISLPR.G "sp|P62701|RS4X_HUMAN,sp|P22090|RS4Y1_HUMAN,sp|Q8TD47|RS4Y2_HUMAN,tr|C9JEH7|C9JEH7_HUMAN" 4 1166.656 0.97 67806 16367 3 1166.656559 389.8926 "40S ribosomal protein S4, X isoform OS=Homo sapiens OX=9606 GN=RPS4X PE=1 SV=2" 11 2856.8 - 1.02E+06 - - - 0.456 - 2.33 0.338 - 221.4 1 2 0 0.0005 10 0 0 0 7.84E+07 8.09E+07 - - - 4.7785 0.9912 221125_WJC_METTL3_EV_vs_WT_F05.16370.16370.2 2.99E-05 18-Aug F.AAQELIEVK[136.11]R[166.11].G "sp|Q86U44|MTA70_HUMAN,tr|F5H6D8|F5H6D8_HUMAN,tr|H0YFV6|H0YFV6_HUMAN,tr|B4DTN4|B4DTN4_HUMAN" 4 1173.6836 0.001 67809 16370 2 1173.684591 587.8491 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 6.19 2857.2 - 471781 - - - 0.8086 - 2.344 0.464 - 357.6 1 1 0 0.0009 10 0 0 0 0.00E+00 4.99E+06 - - - 4.8456 0.9931 221125_WJC_METTL3_EV_vs_WT_F05.16373.16373.2 3.11E-05 30-Nov F.SAPNSYLTGC[160.03]TEEIER[166.11].L sp|Q9HCE5|MET14_HUMAN 1 1835.8235 0.001 67812 16373 2 1835.824167 918.919 N6-adenosine-methyltransferase non-catalytic subunit OS=Homo sapiens OX=9606 GN=METTL14 PE=1 SV=2 4.25 2857.6 - 248181 - - - 0.3562 - 2.114 0.561 - 342 1 1 0 0.0007 16 0 0 0 0.00E+00 3.84E+06 - - - 5.0248 0.8783 221125_WJC_METTL3_EV_vs_WT_F05.16375.16375.2 0.0595 28-Oct K.QSK[136.11]PVTTPEEIAQVA.T "sp|P10809|CH60_HUMAN,tr|A0A7I2V599|A0A7I2V599_HUMAN,tr|E7EXB4|E7EXB4_HUMAN,tr|A0A7I2YQ71|A0A7I2YQ71_HUMAN,tr|E7ESH4|E7ESH4_HUMAN,tr|A0A7I2V5M1|A0A7I2V5M1_HUMAN,tr|A0A7I2V5K3|A0A7I2V5K3_HUMAN,tr|A0A7I2V369|A0A7I2V369_HUMAN" 8 1604.8501 1.4 67813 16375 2 1604.851596 803.4323 "60 kDa heat shock protein, mitochondrial OS=Homo sapiens OX=9606 GN=HSPD1 PE=1 SV=2" 4.53 2857.8 - 591739 - - - 0.9309 - 1.528 0.243 - 175.9 1 1 0 0.0015 15 0 0 0 1.49E+08 1.06E+08 - - - 1.8777 0.9997 221125_WJC_METTL3_EV_vs_WT_F05.16379.16379.3 0.00128 Nov-48 R.VDQLSQQLEDLKK.G "sp|Q96KQ4|ASPP1_HUMAN,tr|A0A3B3ISJ2|A0A3B3ISJ2_HUMAN" 2 1542.8253 2.57 67817 16379 3 1542.821248 515.2824 Apoptosis-stimulating of p53 protein 1 OS=Homo sapiens OX=9606 GN=PPP1R13B PE=1 SV=3 4.56 2858.1 - 937665 - - - -2.6503 - 2.39 0.391 - 147.1 1 2 0 -0.0041 13 0 0 0 7.53E+06 2.93E+06 - - - 5.2605 1 221125_WJC_METTL3_EV_vs_WT_F05.16380.16380.2 3.50E-08 13/24 K.QQQLLNQQVLEQR.Q sp|O00287|RFXAP_HUMAN 1 1623.8693 2.44 67818 16380 2 1623.870543 812.9419 Regulatory factor X-associated protein OS=Homo sapiens OX=9606 GN=RFXAP PE=1 SV=1 6 2858.2 - 407853 - - - 0.7852 - 2.858 0.607 - 628.8 1 2 0 0.0013 13 0 0 0 3.64E+06 1.49E+06 - - - 6.2191 0.9964 221125_WJC_METTL3_EV_vs_WT_F05.16381.16381.2 0.087 Jul-32 K.EKPDSVDGQQPLVNGVP.- "sp|Q06787|FMR1_HUMAN,tr|A8MQB8|A8MQB8_HUMAN,tr|G3V0J0|G3V0J0_HUMAN" 3 1777.8846 2.27 67819 16381 2 1777.88595 889.9496 Synaptic functional regulator FMR1 OS=Homo sapiens OX=9606 GN=FMR1 PE=1 SV=1 4.03 2858.4 - 378512 - - - 0.7351 - 1.197 0.269 - 85.7 1 2 0 0.0013 17 0 0 0 1.36E+08 5.99E+07 - - - 1.4695 1 221125_WJC_METTL3_EV_vs_WT_F05.16383.16383.2 1.12E-11 28-Dec K.EQEMQEC[160.03]TTQIQYLK.Q "sp|Q15007|FL2D_HUMAN,tr|A0A087X1R4|A0A087X1R4_HUMAN" 2 1927.8656 1.19 67821 16383 2 1927.865394 964.9401 Pre-mRNA-splicing regulator WTAP OS=Homo sapiens OX=9606 GN=WTAP PE=1 SV=2 4.25 2858.6 - 201375 - - - -0.0882 - 2.806 0.721 - 410.3 1 2 0 -0.0002 15 0 0 0 3.53E+06 2.96E+06 - - - 6.9029 1 221125_WJC_METTL3_EV_vs_WT_F05.16391.16391.3 2.68E-08 Dec-56 K.EQEMQEC[160.03]TTQIQYLK.Q "sp|Q15007|FL2D_HUMAN,tr|A0A087X1R4|A0A087X1R4_HUMAN" 2 1927.8656 0.76 67827 16391 3 1927.86722 643.6291 Pre-mRNA-splicing regulator WTAP OS=Homo sapiens OX=9606 GN=WTAP PE=1 SV=2 4.25 2859.5 - 553597 - - - 0.859 - 2.383 0.605 - 197.7 1 2 0 0.0017 15 0 0 0 5.59E+06 7.34E+06 - - - 7.5506 1 221125_WJC_METTL3_EV_vs_WT_F05.16392.16392.3 2.57E-11 20/76 R.LVANHVASDISLTGGSVVQR.L sp|Q9UBV2|SE1L1_HUMAN 1 2022.0858 1.04 67828 16392 3 2022.089528 675.0359 Protein sel-1 homolog 1 OS=Homo sapiens OX=9606 GN=SEL1L PE=1 SV=3 6.74 2859.6 - 482331 - - - 1.8427 - 3.801 0.613 - 460.7 1 2 0 0.0037 20 0 0 0 3.82E+06 3.68E+06 - - - 8.6127 0.9956 221125_WJC_METTL3_EV_vs_WT_F05.16393.16393.2 0.000905 14/24 K.AK[136.11]IELLGSYDPQK[136.11].Q sp|P24666|PPAC_HUMAN 1 1476.8159 1.09 67829 16393 2 1476.813285 739.4152 Low molecular weight phosphotyrosine protein phosphatase OS=Homo sapiens OX=9606 GN=ACP1 PE=1 SV=3 6.11 2859.8 - 383832 - - - -1.7673 - 2.847 0.308 - 560.7 1 2 1 -0.0026 13 0 0 0 6.26E+06 5.74E+06 - - - 4.0003 0.9999 221125_WJC_METTL3_EV_vs_WT_F05.16394.16394.3 6.06E-10 17/76 K.MIQDGK[136.11]GDVTITNDGATILK[136.11].Q sp|P50991|TCPD_HUMAN 1 2105.1009 0.28 67830 16394 3 2105.103708 702.7076 T-complex protein 1 subunit delta OS=Homo sapiens OX=9606 GN=CCT4 PE=1 SV=4 4.43 2859.9 - 300088 - - - 1.3244 - 3.384 0.623 - 238.2 1 2 1 0.0028 20 0 0 0 1.25E+08 4.43E+08 - - - 8.4425 0.9997 221125_WJC_METTL3_EV_vs_WT_F05.16398.16398.3 3.48E-05 14/52 K.SGK[136.11]WEGLVYAPPGK[136.11].E "sp|Q9Y2W1|TR150_HUMAN,tr|A0A3B3ITZ9|A0A3B3ITZ9_HUMAN" 2 1503.8057 2.63 67833 16398 3 1503.807374 502.2758 Thyroid hormone receptor-associated protein 3 OS=Homo sapiens OX=9606 GN=THRAP3 PE=1 SV=2 8.22 2860.5 - 1.62E+06 - - - 1.1365 - 2.195 0.472 - 215.8 1 2 1 0.0017 14 0 0 0 4.64E+09 1.76E+09 - - - 5.8912 0.9999 221125_WJC_METTL3_EV_vs_WT_F05.16400.16400.3 3.94E-07 16/52 K.SGKWEGLVYAPPGK.E "sp|Q9Y2W1|TR150_HUMAN,tr|A0A3B3ITZ9|A0A3B3ITZ9_HUMAN" 2 1487.7773 2.63 67834 16400 3 1487.77803 496.933 Thyroid hormone receptor-associated protein 3 OS=Homo sapiens OX=9606 GN=THRAP3 PE=1 SV=2 8.22 2860.7 - 4.69E+06 - - - 0.5142 - 2.381 0.523 - 250.1 1 2 1 0.0008 14 0 0 0 4.62E+09 1.75E+09 - - - 6.6762 0.9986 221125_WJC_METTL3_EV_vs_WT_F05.16401.16401.3 0.00584 Sep-48 K.TTLK[136.11]EEVNELQYR[166.11].Q "sp|Q96EA4|SPDLY_HUMAN,tr|D6RC83|D6RC83_HUMAN,tr|H0YBG5|H0YBG5_HUMAN" 3 1639.8536 0.12 67835 16401 3 1639.851519 547.6252 Protein Spindly OS=Homo sapiens OX=9606 GN=SPDL1 PE=1 SV=2 4.78 2860.7 - 1.62E+06 - - - -1.2818 - 2.172 0.332 - 154.5 1 2 1 -0.0021 13 0 0 0 2.11E+06 1.77E+07 - - - 4.3439 1 221125_WJC_METTL3_EV_vs_WT_F05.16402.16402.2 1.14E-13 17/32 R.SGGGFSSGSAGIINYQR.R sp|P04264|K2C1_HUMAN 1 1656.7856 999 67836 16402 2 1656.785962 829.4001 "Keratin, type II cytoskeletal 1 OS=Homo sapiens OX=9606 GN=KRT1 PE=1 SV=6" 8.46 2860.9 - 822316 - - - 0.2197 - 3.629 0.693 - 1096.8 1 2 0 0.0004 17 0 0 0 2.34E+07 0.00E+00 - - - 7.3283 0.9965 221125_WJC_METTL3_EV_vs_WT_F05.16403.16403.3 0.00379 Dec-48 R.QRYEILTPNAIPK.G "sp|Q7Z406|MYH14_HUMAN,sp|P35580|MYH10_HUMAN,tr|M0QY43|M0QY43_HUMAN" 3 1541.8566 0.9 67837 16403 3 1541.858803 514.9595 Myosin-14 OS=Homo sapiens OX=9606 GN=MYH14 PE=1 SV=2 8.59 2861 - 581563 - - - 1.4431 - 1.848 0.318 - 214.1 1 2 1 0.0022 13 0 0 0 1.45E+07 1.61E+07 - - - 3.7498 0.9843 221125_WJC_METTL3_EV_vs_WT_F05.16404.16404.3 0.0083 Oct-60 K.VVESPDFSKDEDYLGK.V sp|Q9Y6Y8|S23IP_HUMAN 1 1826.8574 0.67 67838 16404 3 1826.850942 609.9598 SEC23-interacting protein OS=Homo sapiens OX=9606 GN=SEC23IP PE=1 SV=1 4.11 2861 - 434155 - - - -3.5487 - 1.689 0.339 - 91.8 1 2 1 -0.0065 16 0 0 0 4.92E+06 7.36E+06 - - - 3.6626 1 221125_WJC_METTL3_EV_vs_WT_F05.16405.16405.2 0.000693 28-Dec K.EQEMQEC[160.03]TTQIQYLK[136.11].Q "sp|Q15007|FL2D_HUMAN,tr|A0A087X1R4|A0A087X1R4_HUMAN" 2 1935.8798 1.19 67839 16405 2 1935.872082 968.9472 Pre-mRNA-splicing regulator WTAP OS=Homo sapiens OX=9606 GN=WTAP PE=1 SV=2 4.25 2861.2 - 348737 - - - -3.9682 - 2.555 0.709 - 444 1 2 0 -0.0077 15 0 0 0 3.53E+06 2.96E+06 - - - 6.5815 0.9975 221125_WJC_METTL3_EV_vs_WT_F05.16407.16407.3 0.00122 Dec-52 M.PSK[136.11]GPLQSVQVFGR[166.11].K "sp|P62249|RS16_HUMAN,tr|M0R210|M0R210_HUMAN,tr|M0R3H0|M0R3H0_HUMAN,tr|Q6IPX4|Q6IPX4_HUMAN" 4 1516.8481 1.47 67841 16407 3 1516.84974 506.6233 40S ribosomal protein S16 OS=Homo sapiens OX=9606 GN=RPS16 PE=1 SV=2 11.01 2861.4 - 258982 - - - 1.0931 - 1.944 0.32 - 215.9 1 2 1 0.0017 14 0 0 0 4.99E+07 3.39E+07 - - - 3.8738 0.9997 221125_WJC_METTL3_EV_vs_WT_F05.16410.16410.3 0.000113 17/60 K.SGFRVPSATC[160.03]QPFTPR.T sp|Q96F45|ZN503_HUMAN 1 1806.8835 44.33 67843 16410 3 1806.887682 603.3018 Zinc finger protein 503 OS=Homo sapiens OX=9606 GN=ZNF503 PE=1 SV=1 10.35 2861.8 - 437220 - - - 2.2935 - 3.164 0.453 - 251.5 1 2 1 0.0041 16 0 0 0 2.66E+07 6.00E+05 - - - 6.5448 0.9988 221125_WJC_METTL3_EV_vs_WT_F05.16413.16413.2 0.00967 Jul-32 K.EK[136.11]PDSVDGQQPLVNGVP.- "sp|Q06787|FMR1_HUMAN,tr|A8MQB8|A8MQB8_HUMAN,tr|G3V0J0|G3V0J0_HUMAN" 3 1785.8988 2.25 67846 16413 2 1785.901157 893.9567 Synaptic functional regulator FMR1 OS=Homo sapiens OX=9606 GN=FMR1 PE=1 SV=1 4.03 2862.1 - 498557 - - - 1.2957 - 1.446 0.353 - 90.6 1 2 0 0.0023 17 0 0 0 1.29E+08 5.73E+07 - - - 2.5542 1 221125_WJC_METTL3_EV_vs_WT_F05.16415.16415.3 3.08E-06 13/68 K.VSHVSTGGGASLELLEGK[136.11].L "sp|P07205|PGK2_HUMAN,sp|P00558|PGK1_HUMAN" 2 1747.9196 1.19 67848 16415 3 1747.920162 583.6471 Phosphoglycerate kinase 2 OS=Homo sapiens OX=9606 GN=PGK2 PE=1 SV=3 5.4 2862.4 - 401718 - - - 0.3341 - 2.554 0.493 - 123.5 1 2 0 0.0006 18 0 0 0 1.93E+07 1.63E+07 - - - 6.3712 0.9967 221125_WJC_METTL3_EV_vs_WT_F05.16417.16417.2 2.78E-07 26-Oct K.DVISAQFENTTTSK.D "sp|Q5VZL5|ZMYM4_HUMAN,tr|H7C1I7|H7C1I7_HUMAN" 2 1539.7417 2.13 67850 16417 2 1539.750629 770.8781 Zinc finger MYM-type protein 4 OS=Homo sapiens OX=9606 GN=ZMYM4 PE=1 SV=1 4.37 2862.6 - 279133 - - - 5.8205 - 2.212 0.58 - 258.8 1 2 0 0.009 14 0 0 0 2.94E+06 1.38E+06 - - - 5.3143 0.9995 221125_WJC_METTL3_EV_vs_WT_F05.16418.16418.2 2.60E-05 30-Oct R.NSTEC[160.03]TLILTEGDSAK.T sp|P11388|TOP2A_HUMAN 1 1737.8091 1.07 67851 16418 2 1737.813661 869.9118 DNA topoisomerase 2-alpha OS=Homo sapiens OX=9606 GN=TOP2A PE=1 SV=3 4.14 2862.8 - 216736 - - - 2.6274 - 1.936 0.516 - 232.9 1 2 0 0.0046 16 0 0 0 1.71E+06 1.60E+06 - - - 4.4749 0.9659 221125_WJC_METTL3_EV_vs_WT_F05.16420.16420.3 0.0279 Oct-48 K.GAAGRPLELSDFR.M "sp|P42167|LAP2B_HUMAN,tr|G5E972|G5E972_HUMAN,tr|H0YJH7|H0YJH7_HUMAN" 3 1387.7208 1.43 67853 16420 3 1387.726194 463.5809 "Lamina-associated polypeptide 2, isoforms beta\gamma OS=Homo sapiens OX=9606 GN=TMPO PE=1 SV=2" 6.07 2863 - 198255 - - - 3.8783 - 1.532 0.23 - 129.2 1 2 0 0.0054 13 0 0 0 6.54E+06 4.58E+06 - - - 2.2593 1 221125_WJC_METTL3_EV_vs_WT_F05.16425.16425.3 1.55E-09 23/76 K.MIQDGKGDVTITNDGATILK.Q sp|P50991|TCPD_HUMAN 1 2089.0725 0.28 67856 16425 3 2089.074114 697.3648 T-complex protein 1 subunit delta OS=Homo sapiens OX=9606 GN=CCT4 PE=1 SV=4 4.43 2863.7 - 2.61E+06 - - - 0.763 - 3.998 0.653 - 420.3 1 2 1 0.0016 20 0 0 0 1.25E+08 4.41E+08 - - - 9.1818 1 221125_WJC_METTL3_EV_vs_WT_F05.16427.16427.3 7.96E-13 22/60 R.FSGSGSGTDFTLKISR.V "sp|A2NJV5|KV229_HUMAN,sp|A0A087WW87|KV240_HUMAN,sp|P06310|KV230_HUMAN,sp|A0A075B6S2|KVD29_HUMAN,sp|P01614|KVD40_HUMAN,sp|P01615|KVD28_HUMAN,sp|A0A075B6S6|KVD30_HUMAN,sp|A0A075B6P5|KV228_HUMAN,sp|A0A0A0MRZ7|KVD26_HUMAN" 9 1658.8264 3.59 67858 16427 3 1658.829141 553.9494 Immunoglobulin kappa variable 2-29 OS=Homo sapiens OX=9606 GN=IGKV2-29 PE=3 SV=2 8.75 2863.8 - 1.06E+06 - - - 1.6524 - 4.401 0.601 - 474.4 1 2 1 0.0027 16 0 0 0 1.25E+07 3.48E+06 - - - 9.042 0.9999 221125_WJC_METTL3_EV_vs_WT_F05.16430.16430.3 4.67E-09 16/56 K.YESLELC[160.03]R[166.11]PVLQQGR[166.11].K "sp|Q00610|CLH1_HUMAN,tr|A0A087WVQ6|A0A087WVQ6_HUMAN" 2 1866.9525 1.27 67861 16430 3 1866.958569 623.3248 Clathrin heavy chain 1 OS=Homo sapiens OX=9606 GN=CLTC PE=1 SV=5 6.14 2864.2 - 663991 - - - 3.247 - 2.51 0.6 - 279.9 1 2 0 0.0061 15 0 0 0 1.33E+07 1.04E+07 - - - 7.6291 0.9995 221125_WJC_METTL3_EV_vs_WT_F05.16433.16433.3 0.000612 Oct-36 R.VK[136.11]DLESLFHR[166.11].S sp|Q03252|LMNB2_HUMAN 1 1260.6945 1.39 67864 16433 3 1260.695449 421.2388 Lamin-B2 OS=Homo sapiens OX=9606 GN=LMNB2 PE=1 SV=4 6.72 2864.6 - 369428 - - - 0.7202 - 2.088 0.39 - 162.6 1 2 1 0.0009 10 0 0 0 2.54E+07 1.83E+07 - - - 5.0379 0.9994 221125_WJC_METTL3_EV_vs_WT_F05.16435.16435.3 0.00747 13/36 R.VKDLESLFHR.S sp|Q03252|LMNB2_HUMAN 1 1242.6721 1.39 67866 16435 3 1242.673968 415.2313 Lamin-B2 OS=Homo sapiens OX=9606 GN=LMNB2 PE=1 SV=4 6.72 2864.9 - 267464 - - - 1.5265 - 2.394 0.371 - 253 1 2 1 0.0019 10 0 0 0 2.54E+07 1.83E+07 - - - 5.2252 0.999 221125_WJC_METTL3_EV_vs_WT_F05.16436.16436.2 0.000404 30-Apr R.NSTEC[160.03]TLILTEGDSAK[136.11].T sp|P11388|TOP2A_HUMAN 1 1745.8233 1.07 67867 16436 2 1745.818926 873.9189 DNA topoisomerase 2-alpha OS=Homo sapiens OX=9606 GN=TOP2A PE=1 SV=3 4.14 2865 - 164059 - - - -2.5025 - 1.593 0.454 - 36.3 1 2 0 -0.0044 16 0 0 0 1.71E+06 1.60E+06 - - - 3.5376 0.9999 221125_WJC_METTL3_EV_vs_WT_F05.16447.16447.3 1.84E-08 14/52 K.IKAPGFAHLAGLDK.M "sp|O75306|NDUS2_HUMAN,tr|A0A7I2V4X8|A0A7I2V4X8_HUMAN,tr|A0A7I2V4G5|A0A7I2V4G5_HUMAN,tr|A0A7I2YQG7|A0A7I2YQG7_HUMAN,tr|A0A7I2V596|A0A7I2V596_HUMAN,tr|A0A7I2YQD8|A0A7I2YQD8_HUMAN" 6 1436.814 1.32 67876 16447 3 1436.814476 479.9453 "NADH dehydrogenase [ubiquinone] iron-sulfur protein 2, mitochondrial OS=Homo sapiens OX=9606 GN=NDUFS2 PE=1 SV=2" 8.6 2866.5 - 228174 - - - 0.3424 - 2.76 0.584 - 156.6 1 2 1 0.0005 14 0 0 0 7.29E+06 5.51E+06 - - - 7.7489 0.9895 221125_WJC_METTL3_EV_vs_WT_F05.16451.16451.2 0.476 20-Jun K.VGLHFHC[160.03]C[160.03]PSK[136.11].S tr|A0A804HJD9|A0A804HJD9_HUMAN 1 1348.626 0.16 67878 16451 2 1348.624734 675.3203 STAM-binding protein OS=Homo sapiens OX=9606 GN=STAMBP PE=4 SV=1 8.05 2867 - 945218 - - - -0.9358 - 1.111 0.185 - 84.5 1 2 0 -0.0013 11 0 0 0 2.33E+06 1.45E+07 - - - 0.6918 0.9976 221125_WJC_METTL3_EV_vs_WT_F05.16452.16452.2 5.26E-05 18-Dec R.SK[136.11]DIFDQLAK[136.11].S "sp|P25205|MCM3_HUMAN,tr|J3KQ69|J3KQ69_HUMAN,tr|A0A499FHX9|A0A499FHX9_HUMAN" 3 1179.647 0.5 67879 16452 2 1179.647464 590.8308 DNA replication licensing factor MCM3 OS=Homo sapiens OX=9606 GN=MCM3 PE=1 SV=3 5.68 2867.2 - 672136 - - - 0.3603 - 1.862 0.446 - 357.8 1 2 1 0.0004 10 0 0 0 4.47E+06 9.01E+06 - - - 4.0702 1 221125_WJC_METTL3_EV_vs_WT_F05.16455.16455.2 6.85E-11 18/38 K.MIQDGK[136.11]GDVTITNDGATILK[136.11].Q sp|P50991|TCPD_HUMAN 1 2105.1009 0.13 67882 16455 2 2105.101093 1053.5577 T-complex protein 1 subunit delta OS=Homo sapiens OX=9606 GN=CCT4 PE=1 SV=4 4.43 2867.5 - 322206 - - - 0.0822 - 3.876 0.692 - 748 1 2 1 0.0002 20 0 0 0 6.57E+05 5.20E+06 - - - 7.4829 0.9945 221125_WJC_METTL3_EV_vs_WT_F05.16459.16459.3 0.0364 Oct-56 K.EPEVTISSIRPISER.A "sp|Q8N6H7|ARFG2_HUMAN,tr|E9PMU9|E9PMU9_HUMAN,tr|E9PQP3|E9PQP3_HUMAN,tr|H0YDN9|H0YDN9_HUMAN,tr|G5E9L0|G5E9L0_HUMAN,tr|A0A0D9SF70|A0A0D9SF70_HUMAN" 6 1711.9105 2.06 67884 16459 3 1711.912224 571.6441 ADP-ribosylation factor GTPase-activating protein 2 OS=Homo sapiens OX=9606 GN=ARFGAP2 PE=1 SV=1 4.79 2868.1 - 450105 - - - 1.0281 - 1.433 0.248 - 109.4 1 2 0 0.0018 15 0 0 0 1.11E+07 5.38E+06 - - - 2.2432 1 221125_WJC_METTL3_EV_vs_WT_F05.16465.16465.3 1.65E-07 17/48 R.VAELSSDDFHLDR.H "sp|Q92896|GSLG1_HUMAN,tr|H3BM42|H3BM42_HUMAN" 2 1502.7001 1.14 67888 16465 3 1502.699626 501.9073 Golgi apparatus protein 1 OS=Homo sapiens OX=9606 GN=GLG1 PE=1 SV=2 4.22 2868.8 - 633556 - - - -0.3401 - 3.176 0.556 - 435.7 1 2 0 -0.0005 13 0 0 0 9.30E+06 8.12E+06 - - - 7.8719 1 221125_WJC_METTL3_EV_vs_WT_F05.16467.16467.3 1.60E-06 23/48 R.VAELSSDDFHLDR[166.11].H "sp|Q92896|GSLG1_HUMAN,tr|H3BM42|H3BM42_HUMAN" 2 1512.7084 1.17 67890 16467 3 1512.707625 505.2434 Golgi apparatus protein 1 OS=Homo sapiens OX=9606 GN=GLG1 PE=1 SV=2 4.22 2869 - 527888 - - - -0.517 - 3.349 0.591 - 1202.8 1 2 0 -0.0008 13 0 0 0 9.48E+06 8.12E+06 - - - 8.4059 0.9998 221125_WJC_METTL3_EV_vs_WT_F05.16469.16469.2 8.06E-05 13/28 R.TNPSPTNPFSSDLQK[136.11].T "sp|P49757|NUMB_HUMAN,tr|G3V3Z8|G3V3Z8_HUMAN" 2 1639.7933 1.06 67892 16469 2 1639.790386 820.9039 Protein numb homolog OS=Homo sapiens OX=9606 GN=NUMB PE=1 SV=2 5.5 2869.3 - 314129 - - - -1.7862 - 2.717 0.539 - 456.3 1 2 0 -0.0029 15 0 0 0 1.30E+07 1.23E+07 - - - 5.4785 1 221125_WJC_METTL3_EV_vs_WT_F05.16470.16470.2 4.27E-11 15/30 K.QGQISSNYDDAMQFSK.K sp|Q9Y2X9|ZN281_HUMAN 1 1817.789 5.99 67893 16470 2 1817.790804 909.9018 Zinc finger protein 281 OS=Homo sapiens OX=9606 GN=ZNF281 PE=1 SV=1 4.21 2869.4 - 313505 - - - 0.977 - 3.199 0.685 - 633.4 1 2 0 0.0018 16 0 0 0 7.86E+06 1.31E+06 - - - 6.9587 1 221125_WJC_METTL3_EV_vs_WT_F05.16472.16472.3 8.76E-06 Nov-52 K.LVRPPVQVYGIEGR.Y "sp|P48047|ATPO_HUMAN,tr|H7C086|H7C086_HUMAN,tr|H7C0C1|H7C0C1_HUMAN,tr|A0A494C0K9|A0A494C0K9_HUMAN" 4 1581.8991 1.15 67895 16472 3 1581.899343 528.307 "ATP synthase subunit O, mitochondrial OS=Homo sapiens OX=9606 GN=ATP5PO PE=1 SV=1" 8.75 2869.7 - 253276 - - - 0.1467 - 2.332 0.462 - 132 1 2 0 0.0002 14 0 0 0 3.01E+06 2.61E+06 - - - 5.941 1 221125_WJC_METTL3_EV_vs_WT_F05.16478.16478.2 4.87E-07 14/28 R.TNPSPTNPFSSDLQK.T "sp|P49757|NUMB_HUMAN,tr|G3V3Z8|G3V3Z8_HUMAN" 2 1631.7791 1.03 67899 16478 2 1631.776445 816.8968 Protein numb homolog OS=Homo sapiens OX=9606 GN=NUMB PE=1 SV=2 5.5 2870.5 - 412302 - - - -1.6363 - 2.814 0.634 - 599.1 1 2 0 -0.0027 15 0 0 0 1.27E+07 1.23E+07 - - - 6.2665 0.9998 221125_WJC_METTL3_EV_vs_WT_F05.16489.16489.4 3.80E-05 15/90 R.NLNTSALQLEHEHLIK.L "sp|Q15643|TRIPB_HUMAN,tr|H0YJ97|H0YJ97_HUMAN" 2 1858.9901 1.22 67908 16489 4 1858.986976 465.7548 Thyroid receptor-interacting protein 11 OS=Homo sapiens OX=9606 GN=TRIP11 PE=1 SV=3 6 2871.8 - 520236 - - - -1.6864 - 2.935 0.393 - 195.4 1 2 0 -0.0031 16 0 0 0 2.70E+08 2.21E+08 - - - 3.0251 0.9873 221125_WJC_METTL3_EV_vs_WT_F05.16490.16490.3 0.0543 Sep-76 K.MIQDGK[136.11]GDVTITNDGATILK.Q sp|P50991|TCPD_HUMAN 1 2097.0867 - 67909 16490 3 2097.085974 700.0362 T-complex protein 1 subunit delta OS=Homo sapiens OX=9606 GN=CCT4 PE=1 SV=4 4.43 2871.9 - 458690 - - - -0.3557 - 1.492 0.278 - 43.4 1 2 1 -0.0007 20 0 0 0 - - - - - 2.6099 0.9986 221125_WJC_METTL3_EV_vs_WT_F05.16491.16491.4 0.0387 15/120 R.LTALAEDRPLFDGPSRPSVAR.D "sp|O94913|PCF11_HUMAN,tr|E9PKN0|E9PKN0_HUMAN,tr|E9PQ01|E9PQ01_HUMAN" 3 2267.2022 0.41 67910 16491 4 2267.202419 567.8078 Pre-mRNA cleavage complex 2 protein Pcf11 OS=Homo sapiens OX=9606 GN=PCF11 PE=1 SV=3 6.12 2872.1 - 435769 - - - 0.0838 - 2.098 0.281 - 109 1 2 0 0.0002 21 0 0 0 6.50E+06 1.58E+07 - - - 1.9168 0.9997 221125_WJC_METTL3_EV_vs_WT_F05.16506.16506.3 0.000942 18/52 M.PSKGPLQSVQVFGR.K "sp|P62249|RS16_HUMAN,tr|M0R210|M0R210_HUMAN,tr|M0R3H0|M0R3H0_HUMAN,tr|Q6IPX4|Q6IPX4_HUMAN" 4 1498.8256 1.48 67921 16506 3 1498.822081 500.6158 40S ribosomal protein S16 OS=Homo sapiens OX=9606 GN=RPS16 PE=1 SV=2 11.01 2873.8 - 538718 - - - -2.3558 - 2.786 0.479 - 444.4 1 2 1 -0.0035 14 0 0 0 5.01E+07 3.38E+07 - - - 6.6023 0.9995 221125_WJC_METTL3_EV_vs_WT_F05.16507.16507.3 0.00151 15/52 R.VKEDDLDVVLSPQR.R "sp|Q9NRA8|4ET_HUMAN,tr|B1AKL5|B1AKL5_HUMAN,tr|B1AKL4|B1AKL4_HUMAN" 3 1611.8468 1.29 67922 16507 3 1611.845529 538.2895 Eukaryotic translation initiation factor 4E transporter OS=Homo sapiens OX=9606 GN=EIF4ENIF1 PE=1 SV=2 4.23 2873.9 - 535790 - - - -0.7892 - 2.585 0.364 - 328.2 1 2 1 -0.0013 14 0 0 0 1.27E+08 9.90E+07 - - - 5.1218 1 221125_WJC_METTL3_EV_vs_WT_F05.16511.16511.3 7.24E-08 14/60 R.NLNTSALQLEHEHLIK.L "sp|Q15643|TRIPB_HUMAN,tr|H0YJ97|H0YJ97_HUMAN" 2 1858.9901 1.2 67924 16511 3 1858.986808 620.6706 Thyroid receptor-interacting protein 11 OS=Homo sapiens OX=9606 GN=TRIP11 PE=1 SV=3 6 2874.4 - 1.53E+06 - - - -1.7768 - 3.022 0.511 - 158.1 1 2 0 -0.0033 16 0 0 0 1.12E+08 9.34E+07 - - - 7.0739 0.9998 221125_WJC_METTL3_EV_vs_WT_F05.16516.16516.3 3.32E-05 18/52 R.VK[136.11]EDDLDVVLSPQR[166.11].R "sp|Q9NRA8|4ET_HUMAN,tr|B1AKL5|B1AKL5_HUMAN,tr|B1AKL4|B1AKL4_HUMAN" 3 1629.8693 1.29 67927 16516 3 1629.86998 544.297 Eukaryotic translation initiation factor 4E transporter OS=Homo sapiens OX=9606 GN=EIF4ENIF1 PE=1 SV=2 4.23 2875.1 - 505748 - - - 0.435 - 2.564 0.476 - 512 1 2 1 0.0007 14 0 0 0 1.27E+08 9.90E+07 - - - 6.349 0.795 221125_WJC_METTL3_EV_vs_WT_F05.16521.16521.2 0.000873 24-Aug R.EESTR[166.11]LK[136.11]EEGNEQ.F "sp|Q99614|TTC1_HUMAN,tr|A0A804HKC5|A0A804HKC5_HUMAN,tr|A0A804HHT7|A0A804HHT7_HUMAN,tr|A0A804HIB8|A0A804HIB8_HUMAN,tr|A0A804HKI4|A0A804HKI4_HUMAN" 5 1565.7288 1.2 67929 16521 2 1565.727348 783.8717 Tetratricopeptide repeat protein 1 OS=Homo sapiens OX=9606 GN=TTC1 PE=1 SV=1 4.33 2875.8 - 509721 - - - -0.9363 - 1.65 0.426 - 175.1 1 1 2 -0.0015 13 0 0 0 1.25E+07 1.03E+07 - - - 3.4722 0.999 221125_WJC_METTL3_EV_vs_WT_F05.16523.16523.3 0.0839 13/60 R.VFDK[136.11]DGNGYISAAELR[166.11].H "sp|P0DP25|CALM3_HUMAN,sp|P0DP23|CALM1_HUMAN,sp|P0DP24|CALM2_HUMAN,tr|G3V361|G3V361_HUMAN,tr|A0A590UJI2|A0A590UJI2_HUMAN,tr|Q96HY3|Q96HY3_HUMAN,tr|E7EMB3|E7EMB3_HUMAN" 7 1771.886 0.92 67930 16523 3 1771.889937 591.6359 Calmodulin-3 OS=Homo sapiens OX=9606 GN=CALM3 PE=1 SV=1 4.56 2876 - 1.01E+06 - - - 2.231 - 2.266 0.414 - 162.2 1 2 1 0.004 16 0 0 0 2.83E+07 3.09E+07 - - - 5.2535 1 221125_WJC_METTL3_EV_vs_WT_F05.16525.16525.3 3.74E-07 19/80 R.LC[160.03]QGEELQSDRDETGAYLIDR.D "sp|Q8N5Z5|KCD17_HUMAN,tr|H7C323|H7C323_HUMAN,tr|A0A087WX35|A0A087WX35_HUMAN,tr|H0Y731|H0Y731_HUMAN" 4 2467.1285 6.31 67932 16525 3 2467.12911 823.3835 BTB\POZ domain-containing protein KCTD17 OS=Homo sapiens OX=9606 GN=KCTD17 PE=1 SV=3 4.02 2876.2 - 1.25E+06 - - - 0.2343 - 3.503 0.644 - 422.4 1 2 1 0.0006 21 0 0 0 3.65E+07 5.78E+06 - - - 8.7253 1 221125_WJC_METTL3_EV_vs_WT_F05.16526.16526.3 4.82E-07 16/48 K.HQTLQGVAFPISR.E "sp|Q12792|TWF1_HUMAN,tr|F8VS81|F8VS81_HUMAN" 2 1452.7837 0.61 67933 16526 3 1452.780611 485.2685 Twinfilin-1 OS=Homo sapiens OX=9606 GN=TWF1 PE=1 SV=3 9.76 2876.4 - 435694 - - - -2.1586 - 3.141 0.555 - 450.3 1 2 0 -0.0031 13 0 0 0 1.24E+07 2.02E+07 - - - 7.83 0.9994 221125_WJC_METTL3_EV_vs_WT_F05.16530.16530.3 3.59E-09 18/68 R.EGDVTSGMVKDPPDVLDR.Q sp|Q96KR1|ZFR_HUMAN 1 1928.915 1.79 67935 16530 3 1928.906089 643.9789 Zinc finger RNA-binding protein OS=Homo sapiens OX=9606 GN=ZFR PE=1 SV=2 4.04 2876.9 - 776531 - - - -4.5974 - 3.165 0.588 - 299.8 1 2 1 -0.0089 18 0 0 0 2.46E+07 1.38E+07 - - - 7.9621 1 221125_WJC_METTL3_EV_vs_WT_F05.16532.16532.3 0.00124 Nov-52 K.NSVTPDMMEEMYKK.A "sp|P46777|RL5_HUMAN,tr|A0A2R8Y6J3|A0A2R8Y6J3_HUMAN" 2 1701.7412 0.78 67937 16532 3 1701.738792 568.2543 60S ribosomal protein L5 OS=Homo sapiens OX=9606 GN=RPL5 PE=1 SV=3 4.68 2877.1 - 605726 - - - -1.4238 - 2.363 0.491 - 122.8 1 2 0 -0.0024 14 0 0 0 2.55E+07 3.25E+07 - - - 6.2988 1 221125_WJC_METTL3_EV_vs_WT_F05.16537.16537.3 1.41E-06 15/48 K.HQTLQGVAFPISR[166.11].E "sp|Q12792|TWF1_HUMAN,tr|F8VS81|F8VS81_HUMAN" 2 1462.792 0.65 67940 16537 3 1462.787978 488.6046 Twinfilin-1 OS=Homo sapiens OX=9606 GN=TWF1 PE=1 SV=3 9.76 2877.8 - 720560 - - - -2.7612 - 3.202 0.547 - 330.7 1 2 0 -0.004 13 0 0 0 1.24E+07 1.89E+07 - - - 7.7927 1 221125_WJC_METTL3_EV_vs_WT_F05.16538.16538.3 8.25E-09 15/44 R.C[160.03]EFC[160.03]GEFFENR[166.11]K[136.11].G "sp|O95785|WIZ_HUMAN,sp|O95785|WIZ_HUMAN,tr|A0A669KBG4|A0A669KBG4_HUMAN,tr|A0A669KBG4|A0A669KBG4_HUMAN,tr|A0A2R8YFV2|A0A2R8YFV2_HUMAN,tr|A0A2R8YFV2|A0A2R8YFV2_HUMAN,tr|A0A669KAV7|A0A669KAV7_HUMAN,tr|A0A669KAV7|A0A669KAV7_HUMAN,tr|M0QXA7|M0QXA7_HUMAN,tr|M0QXA7|M0QXA7_HUMAN,tr|A0A669KBH9|A0A669KBH9_HUMAN,tr|A0A669KBH9|A0A669KBH9_HUMAN,tr|B9EGQ5|B9EGQ5_HUMAN,tr|B9EGQ5|B9EGQ5_HUMAN" 14 1639.6878 1.71 67941 16538 3 1639.681848 547.5699 Protein Wiz OS=Homo sapiens OX=9606 GN=WIZ PE=1 SV=2 4.79 2877.9 - 707255 - - - -3.6409 - 2.945 0.67 - 226.9 1 2 0 -0.006 12 0 0 0 1.97E+07 1.15E+07 - - - 9.0021 1 221125_WJC_METTL3_EV_vs_WT_F05.16542.16542.3 6.00E-06 15/44 R.C[160.03]EFC[160.03]GEFFENRK.G "sp|O95785|WIZ_HUMAN,sp|O95785|WIZ_HUMAN,tr|A0A669KBG4|A0A669KBG4_HUMAN,tr|A0A669KBG4|A0A669KBG4_HUMAN,tr|A0A2R8YFV2|A0A2R8YFV2_HUMAN,tr|A0A2R8YFV2|A0A2R8YFV2_HUMAN,tr|A0A669KAV7|A0A669KAV7_HUMAN,tr|A0A669KAV7|A0A669KAV7_HUMAN,tr|M0QXA7|M0QXA7_HUMAN,tr|M0QXA7|M0QXA7_HUMAN,tr|A0A669KBH9|A0A669KBH9_HUMAN,tr|A0A669KBH9|A0A669KBH9_HUMAN,tr|B9EGQ5|B9EGQ5_HUMAN,tr|B9EGQ5|B9EGQ5_HUMAN" 14 1621.6653 1.53 67943 16542 3 1621.665171 541.5624 Protein Wiz OS=Homo sapiens OX=9606 GN=WIZ PE=1 SV=2 4.79 2878.5 - 851089 - - - -0.1091 - 2.706 0.633 - 236.3 1 2 0 -0.0002 12 0 0 0 1.74E+07 1.14E+07 - - - 8.3566 0.9999 221125_WJC_METTL3_EV_vs_WT_F05.16547.16547.3 3.08E-06 15/44 R.NNILTDHFQYSR.Q "sp|Q96K37|S35E1_HUMAN,tr|H7C1I0|H7C1I0_HUMAN" 2 1506.7215 1.14 67946 16547 3 1506.720176 503.2478 Solute carrier family 35 member E1 OS=Homo sapiens OX=9606 GN=SLC35E1 PE=1 SV=2 6.74 2879.1 - 959887 - - - -0.9059 - 2.845 0.391 - 502.6 1 2 0 -0.0014 12 0 0 0 1.51E+07 1.33E+07 - - - 5.797 0.9999 221125_WJC_METTL3_EV_vs_WT_F05.16550.16550.4 2.50E-06 14/90 R.NLNTSALQLEHEHLIK[136.11].L "sp|Q15643|TRIPB_HUMAN,tr|H0YJ97|H0YJ97_HUMAN" 2 1867.0043 1.22 67949 16550 4 1867.000504 467.7584 Thyroid receptor-interacting protein 11 OS=Homo sapiens OX=9606 GN=TRIP11 PE=1 SV=3 6 2879.3 - 1.01E+07 - - - -2.0391 - 3.011 0.474 - 174.1 1 2 0 -0.0038 16 0 0 0 2.70E+08 2.21E+08 - - - 3.7389 0.9999 221125_WJC_METTL3_EV_vs_WT_F05.16551.16551.3 1.03E-08 16/52 K.NSVTPDMMEEMYK[136.11]K[136.11].A "sp|P46777|RL5_HUMAN,tr|A0A2R8Y6J3|A0A2R8Y6J3_HUMAN" 2 1717.7696 0.78 67950 16551 3 1717.763212 573.5971 60S ribosomal protein L5 OS=Homo sapiens OX=9606 GN=RPL5 PE=1 SV=3 4.68 2879.4 - 1.10E+06 - - - -3.7275 - 3.064 0.606 - 471.9 1 2 0 -0.0064 14 0 0 0 2.55E+07 3.25E+07 - - - 8.2702 1 221125_WJC_METTL3_EV_vs_WT_F05.16552.16552.3 1.10E-13 21/68 R.QAHLC[160.03]VLASNC[160.03]DEPMYVK.L sp|P25398|RS12_HUMAN 1 2133.9646 1.87 67951 16552 3 2133.959886 712.3288 40S ribosomal protein S12 OS=Homo sapiens OX=9606 GN=RPS12 PE=1 SV=3 5.32 2879.5 - 1.06E+06 - - - -2.1936 - 4.127 0.665 - 645.2 1 2 0 -0.0047 18 0 0 0 4.58E+08 2.45E+08 - - - 9.4826 1 221125_WJC_METTL3_EV_vs_WT_F05.16556.16556.3 2.48E-14 20/68 R.QAHLC[160.03]VLASNC[160.03]DEPMYVK[136.11].L sp|P25398|RS12_HUMAN 1 2141.9788 1.87 67953 16556 3 2141.977523 715.0002 40S ribosomal protein S12 OS=Homo sapiens OX=9606 GN=RPS12 PE=1 SV=3 5.32 2880 - 942804 - - - -0.5808 - 3.95 0.704 - 585.4 1 2 0 -0.0012 18 0 0 0 4.58E+08 2.45E+08 - - - 9.8093 0.9991 221125_WJC_METTL3_EV_vs_WT_F05.16561.16561.3 0.000867 13/56 K.HVVTLLQVQDC[160.03]HVLK[136.11].Y "sp|P09001|RM03_HUMAN,tr|D6RC14|D6RC14_HUMAN,tr|E7ETU7|E7ETU7_HUMAN,tr|H0Y9G6|H0Y9G6_HUMAN,tr|D6RBQ5|D6RBQ5_HUMAN" 5 1795.9858 1.36 67956 16561 3 1795.993151 599.6692 "39S ribosomal protein L3, mitochondrial OS=Homo sapiens OX=9606 GN=MRPL3 PE=1 SV=1" 6.91 2880.7 - 873322 - - - 4.0797 - 2.286 0.397 - 98.7 1 2 0 0.0073 15 0 0 0 1.42E+07 1.04E+07 - - - 5.1216 0.9997 221125_WJC_METTL3_EV_vs_WT_F05.16562.16562.2 0.000377 16-Oct K.TLLDIDNTR.M sp|P35527|K1C9_HUMAN 1 1059.556 999 67957 16562 2 1059.555972 530.7853 "Keratin, type I cytoskeletal 9 OS=Homo sapiens OX=9606 GN=KRT9 PE=1 SV=3" 4.21 2880.8 - 1.29E+06 - - - -0.0623 - 1.734 0.411 - 314.9 1 2 0 -0.0001 9 0 0 0 2.57E+07 0.00E+00 - - - 3.6691 0.9998 221125_WJC_METTL3_EV_vs_WT_F05.16564.16564.4 7.29E-08 21/72 R.C[160.03]ILPFDK[136.11]ETGFHR[166.11].G "sp|Q9GZT3|SLIRP_HUMAN,tr|H0YJW7|H0YJW7_HUMAN,tr|A0A087WUN7|A0A087WUN7_HUMAN,tr|G3V2S9|G3V2S9_HUMAN,tr|H0YJ40|H0YJ40_HUMAN,tr|G3V4X6|G3V4X6_HUMAN" 6 1636.8151 1.17 67959 16564 4 1636.810934 410.211 "SRA stem-loop-interacting RNA-binding protein, mitochondrial OS=Homo sapiens OX=9606 GN=SLIRP PE=1 SV=1" 6.74 2881 - 689802 - - - -2.525 - 3.546 0.536 - 607.3 1 2 1 -0.0041 13 0 0 0 1.37E+08 1.17E+08 - - - 4.3595 0.9999 221125_WJC_METTL3_EV_vs_WT_F05.16565.16565.4 1.64E-06 25/72 R.C[160.03]ILPFDKETGFHR.G "sp|Q9GZT3|SLIRP_HUMAN,tr|H0YJW7|H0YJW7_HUMAN,tr|A0A087WUN7|A0A087WUN7_HUMAN,tr|G3V2S9|G3V2S9_HUMAN,tr|H0YJ40|H0YJ40_HUMAN,tr|G3V4X6|G3V4X6_HUMAN" 6 1618.7926 1.19 67960 16565 4 1618.792472 405.7054 "SRA stem-loop-interacting RNA-binding protein, mitochondrial OS=Homo sapiens OX=9606 GN=SLIRP PE=1 SV=1" 6.74 2881.2 - 656729 - - - -0.0772 - 3.672 0.535 - 888.9 1 2 1 -0.0001 13 0 0 0 1.39E+08 1.17E+08 - - - 4.3649 0.9999 221125_WJC_METTL3_EV_vs_WT_F05.16570.16570.3 4.02E-05 Nov-48 K.EFNPTKPLLSVNK.S "sp|Q8WWM7|ATX2L_HUMAN,tr|H3BUF6|H3BUF6_HUMAN" 2 1485.8191 1.34 67963 16570 3 1485.817136 496.2803 Ataxin-2-like protein OS=Homo sapiens OX=9606 GN=ATXN2L PE=1 SV=2 8.69 2881.8 - 1.28E+06 - - - -1.3413 - 2.051 0.435 - 141.7 1 2 0 -0.002 13 0 0 0 3.83E+07 2.86E+07 - - - 5.3369 0.9999 221125_WJC_METTL3_EV_vs_WT_F05.16572.16572.3 5.48E-07 21/48 R.C[160.03]ILPFDKETGFHR.G "sp|Q9GZT3|SLIRP_HUMAN,tr|H0YJW7|H0YJW7_HUMAN,tr|A0A087WUN7|A0A087WUN7_HUMAN,tr|G3V2S9|G3V2S9_HUMAN,tr|H0YJ40|H0YJ40_HUMAN,tr|G3V4X6|G3V4X6_HUMAN" 6 1618.7926 1.15 67965 16572 3 1618.793153 540.6048 "SRA stem-loop-interacting RNA-binding protein, mitochondrial OS=Homo sapiens OX=9606 GN=SLIRP PE=1 SV=1" 6.74 2882.1 - 984712 - - - 0.3435 - 3.224 0.499 - 593.9 1 2 1 0.0006 13 0 0 0 8.20E+07 7.13E+07 - - - 7.2771 0.9997 221125_WJC_METTL3_EV_vs_WT_F05.16576.16576.3 0.000214 Oct-48 R.NATSLQHLLSGAK[136.11].M sp|Q6N069|NAA16_HUMAN 1 1346.7398 0.29 67969 16576 3 1346.737375 449.9205 "N-alpha-acetyltransferase 16, NatA auxiliary subunit OS=Homo sapiens OX=9606 GN=NAA16 PE=1 SV=2" 8.76 2882.5 - 340066 - - - -1.7732 - 1.935 0.386 - 121 1 2 0 -0.0024 13 0 0 0 1.34E+06 4.65E+06 - - - 4.6326 1 221125_WJC_METTL3_EV_vs_WT_F05.16579.16579.3 5.74E-06 15/48 K.EFNPTK[136.11]PLLSVNK[136.11].S "sp|Q8WWM7|ATX2L_HUMAN,tr|H3BUF6|H3BUF6_HUMAN" 2 1501.8475 1.34 67970 16579 3 1501.847549 501.6231 Ataxin-2-like protein OS=Homo sapiens OX=9606 GN=ATXN2L PE=1 SV=2 8.69 2882.9 - 1.17E+06 - - - 0.0133 - 2.34 0.485 - 285 1 2 0 0 13 0 0 0 3.84E+07 2.87E+07 - - - 6.2523 0.997 221125_WJC_METTL3_EV_vs_WT_F05.16581.16581.4 0.0593 13/84 R.TFYPHHPQMLGFDPR.W sp|Q5JSZ5|PRC2B_HUMAN 1 1841.8672 1.62 67972 16581 4 1841.86743 461.4741 Protein PRRC2B OS=Homo sapiens OX=9606 GN=PRRC2B PE=1 SV=2 6.61 2883.1 - 915263 - - - 0.1471 - 1.769 0.251 - 74.5 1 2 0 0.0003 15 0 0 0 1.70E+07 1.05E+07 - - - 1.6147 1 221125_WJC_METTL3_EV_vs_WT_F05.16582.16582.3 4.29E-05 14/48 K.K[136.11]TFSYAGFEMQPK[136.11].K sp|Q99832|TCPH_HUMAN 1 1548.7618 1.42 67973 16582 3 1548.761396 517.2612 T-complex protein 1 subunit eta OS=Homo sapiens OX=9606 GN=CCT7 PE=1 SV=2 8.5 2883.2 - 876882 - - - -0.2292 - 2.479 0.531 - 215.3 1 2 0 -0.0004 13 0 0 0 3.45E+07 2.42E+07 - - - 6.9215 1 221125_WJC_METTL3_EV_vs_WT_F05.16585.16585.2 8.99E-13 14/30 K.C[160.03]SVC[160.03]PDYDLC[160.03]SVC[160.03]EGK.G "sp|Q13501|SQSTM_HUMAN,tr|E3W990|E3W990_HUMAN,tr|E9PFW8|E9PFW8_HUMAN,tr|E7EMC7|E7EMC7_HUMAN,tr|C9JRJ8|C9JRJ8_HUMAN" 5 1947.7471 2.09 67976 16585 2 1947.747411 974.8808 Sequestosome-1 OS=Homo sapiens OX=9606 GN=SQSTM1 PE=1 SV=1 4.03 2883.6 - 359263 - - - 0.1566 - 2.903 0.788 - 591.6 1 2 0 0.0003 16 0 0 0 5.38E+06 2.58E+06 - - - 7.4813 1 221125_WJC_METTL3_EV_vs_WT_F05.16586.16586.2 1.18E-06 13/26 R.VK[136.11]EDDLDVVLSPQR[166.11].R "sp|Q9NRA8|4ET_HUMAN,tr|B1AKL5|B1AKL5_HUMAN,tr|B1AKL4|B1AKL4_HUMAN" 3 1629.8693 1.73 67977 16586 2 1629.869448 815.9419 Eukaryotic translation initiation factor 4E transporter OS=Homo sapiens OX=9606 GN=EIF4ENIF1 PE=1 SV=2 4.23 2883.7 - 275788 - - - 0.1086 - 3.024 0.627 - 384.6 1 2 1 0.0002 14 0 0 0 3.29E+06 1.90E+06 - - - 6.4489 0.9975 221125_WJC_METTL3_EV_vs_WT_F05.16588.16588.3 0.0107 Jul-68 R.ASLLQNESTNEQLQIHYK.V "sp|Q9BT78|CSN4_HUMAN,tr|D6RD63|D6RD63_HUMAN,tr|D6RFN0|D6RFN0_HUMAN,tr|D6RAX7|D6RAX7_HUMAN" 4 2115.0596 0.32 67979 16588 3 2115.061521 706.0272 COP9 signalosome complex subunit 4 OS=Homo sapiens OX=9606 GN=COPS4 PE=1 SV=1 5.4 2884 - 147034 - - - 0.886 - 1.746 0.249 - 50.7 1 2 0 0.0019 18 0 0 0 2.93E+06 9.05E+06 - - - 2.7034 0.9996 221125_WJC_METTL3_EV_vs_WT_F05.16593.16593.4 0.0108 14/78 K.DTSLYR[166.11]PALEELR[166.11]R[166.11].Q "sp|Q13200|PSMD2_HUMAN,tr|C9JPC0|C9JPC0_HUMAN,tr|H7C2Q3|H7C2Q3_HUMAN" 3 1747.9359 0.5 67982 16593 4 1747.935895 437.9913 26S proteasome non-ATPase regulatory subunit 2 OS=Homo sapiens OX=9606 GN=PSMD2 PE=1 SV=3 6.18 2884.6 - 806092 - - - -0.0269 - 1.794 0.345 - 64.8 1 2 0 0 14 0 0 0 4.66E+06 9.31E+06 - - - 2.4416 0.9999 221125_WJC_METTL3_EV_vs_WT_F05.16594.16594.3 0.00595 17/48 K.NR[166.11]EPVQLETLSIR[166.11].G "sp|P62314|SMD1_HUMAN,tr|J3QLI9|J3QLI9_HUMAN" 2 1573.8691 2.03 67983 16594 3 1573.869416 525.6303 Small nuclear ribonucleoprotein Sm D1 OS=Homo sapiens OX=9606 GN=SNRPD1 PE=1 SV=1 6.14 2884.7 - 478996 - - - 0.204 - 3.264 0.481 - 666.3 1 2 1 0.0003 13 0 0 0 5.25E+07 2.58E+07 - - - 7.1099 0.9999 221125_WJC_METTL3_EV_vs_WT_F05.16595.16595.3 2.98E-06 Dec-60 R.AYRDEMLTTNVPEIQR.T "sp|Q14562|DHX8_HUMAN,tr|F5H658|F5H658_HUMAN" 2 1934.952 1.68 67984 16595 3 1934.950276 645.9913 ATP-dependent RNA helicase DHX8 OS=Homo sapiens OX=9606 GN=DHX8 PE=1 SV=1 4.68 2884.8 - 423659 - - - -0.8967 - 2.546 0.525 - 123.5 1 2 1 -0.0017 16 0 0 0 6.49E+06 3.85E+06 - - - 6.7906 1 221125_WJC_METTL3_EV_vs_WT_F05.16596.16596.2 2.39E-16 16/34 R.QAHLC[160.03]VLASNC[160.03]DEPMYVK[136.11].L sp|P25398|RS12_HUMAN 1 2141.9788 2 67985 16596 2 2141.978117 1071.9967 40S ribosomal protein S12 OS=Homo sapiens OX=9606 GN=RPS12 PE=1 SV=3 5.32 2885 - 248599 - - - -0.3035 - 3.431 0.775 - 634.2 1 2 0 -0.0006 18 0 0 0 5.33E+06 2.66E+06 - - - 7.796 0.9999 221125_WJC_METTL3_EV_vs_WT_F05.16598.16598.3 2.51E-06 15/48 R.C[160.03]ILPFDK[136.11]ETGFHR[166.11].G "sp|Q9GZT3|SLIRP_HUMAN,tr|H0YJW7|H0YJW7_HUMAN,tr|A0A087WUN7|A0A087WUN7_HUMAN,tr|G3V2S9|G3V2S9_HUMAN,tr|H0YJ40|H0YJ40_HUMAN,tr|G3V4X6|G3V4X6_HUMAN" 6 1636.8151 1.14 67986 16598 3 1636.816276 546.6123 "SRA stem-loop-interacting RNA-binding protein, mitochondrial OS=Homo sapiens OX=9606 GN=SLIRP PE=1 SV=1" 6.74 2885.2 - 5.21E+06 - - - 0.7386 - 2.88 0.55 - 294.8 1 2 1 0.0012 13 0 0 0 8.22E+07 7.20E+07 - - - 7.5396 0.9999 221125_WJC_METTL3_EV_vs_WT_F05.16600.16600.3 2.48E-07 15/52 K.LGKDAVEDLESVGK.G sp|P81605|DCD_HUMAN 1 1458.7566 2049.91 67988 16600 3 1458.758534 487.2595 Dermcidin OS=Homo sapiens OX=9606 GN=DCD PE=1 SV=2 4.32 2885.3 - 2.20E+06 - - - 1.3333 - 2.62 0.545 - 200.6 1 2 1 0.0019 14 0 0 0 3.27E+08 1.59E+05 - - - 7.1753 1 221125_WJC_METTL3_EV_vs_WT_F05.16601.16601.3 0.000656 16/60 R.VQTSSVAALGNVKPFR.T "sp|O95201|ZN205_HUMAN,tr|C9JEY6|C9JEY6_HUMAN,tr|I3L417|I3L417_HUMAN" 3 1672.9261 1.29 67989 16601 3 1672.925146 558.6493 Zinc finger protein 205 OS=Homo sapiens OX=9606 GN=ZNF205 PE=1 SV=2 11 2885.5 - 486197 - - - -0.5428 - 3.1 0.415 - 342.8 1 2 0 -0.0009 16 0 0 0 3.51E+06 2.73E+06 - - - 6.0696 0.9987 221125_WJC_METTL3_EV_vs_WT_F05.16602.16602.3 0.0403 Oct-60 R.TTTGDVQVLGLVHTQK.L "sp|P11717|MPRI_HUMAN,tr|S4R328|S4R328_HUMAN" 2 1695.9155 0.54 67990 16602 3 1695.918639 566.3125 Cation-independent mannose-6-phosphate receptor OS=Homo sapiens OX=9606 GN=IGF2R PE=1 SV=3 6.41 2885.6 - 484861 - - - 1.822 - 1.867 0.301 - 73 1 2 0 0.0031 16 0 0 0 5.17E+06 9.52E+06 - - - 3.497 1 221125_WJC_METTL3_EV_vs_WT_F05.16604.16604.2 2.69E-10 18/34 R.QAHLC[160.03]VLASNC[160.03]DEPMYVK.L sp|P25398|RS12_HUMAN 1 2133.9646 2 67992 16604 2 2133.9649 1067.9896 40S ribosomal protein S12 OS=Homo sapiens OX=9606 GN=RPS12 PE=1 SV=3 5.32 2885.9 - 441206 - - - 0.156 - 3.959 0.737 - 903.9 1 2 0 0.0003 18 0 0 0 5.33E+06 2.66E+06 - - - 7.8673 1 221125_WJC_METTL3_EV_vs_WT_F05.16606.16606.2 1.59E-08 13/26 R.VKEDDLDVVLSPQR.R "sp|Q9NRA8|4ET_HUMAN,tr|B1AKL5|B1AKL5_HUMAN,tr|B1AKL4|B1AKL4_HUMAN" 3 1611.8468 1.51 67994 16606 2 1611.850327 806.9307 Eukaryotic translation initiation factor 4E transporter OS=Homo sapiens OX=9606 GN=EIF4ENIF1 PE=1 SV=2 4.23 2886.1 - 324018 - - - 2.1876 - 2.952 0.599 - 391.4 1 2 1 0.0035 14 0 0 0 6.12E+06 4.06E+06 - - - 6.1805 0.9903 221125_WJC_METTL3_EV_vs_WT_F05.16608.16608.3 0.0377 Nov-60 R.AYR[166.11]DEMLTTNVPEIQR[166.11].T "sp|Q14562|DHX8_HUMAN,tr|F5H658|F5H658_HUMAN" 2 1954.9686 1.68 67996 16608 3 1954.96832 652.6635 ATP-dependent RNA helicase DHX8 OS=Homo sapiens OX=9606 GN=DHX8 PE=1 SV=1 4.68 2886.4 - 304755 - - - -0.1182 - 1.989 0.223 - 110.9 1 2 1 -0.0002 16 0 0 0 6.49E+06 3.85E+06 - - - 2.7905 0.8501 221125_WJC_METTL3_EV_vs_WT_F05.16609.16609.4 0.0263 Oct-72 R.EK[136.11]LTLLHYDPVVK[136.11].Q sp|O75394|RM33_HUMAN 1 1569.9101 1.16 67997 16609 4 1569.910158 393.4848 "39S ribosomal protein L33, mitochondrial OS=Homo sapiens OX=9606 GN=MRPL33 PE=1 SV=1" 6.85 2886.5 - 299980 - - - 0.0178 - 1.773 0.142 - 74.8 1 2 1 0 13 0 0 0 4.22E+06 3.63E+06 - - - 0.6743 0.8843 221125_WJC_METTL3_EV_vs_WT_F05.16610.16610.3 0.811 Aug-68 R.EGDVTSGMVK[136.11]DPPDVLDR[166.11].Q sp|Q96KR1|ZFR_HUMAN 1 1946.9374 1.79 67998 16610 3 1946.938851 649.9864 Zinc finger RNA-binding protein OS=Homo sapiens OX=9606 GN=ZFR PE=1 SV=2 4.04 2886.6 - 297486 - - - 0.7314 - 1.404 0.163 - 63.6 1 2 1 0.0014 18 0 0 0 2.46E+07 1.38E+07 - - - 1.2018 0.9998 221125_WJC_METTL3_EV_vs_WT_F05.16612.16612.3 7.74E-08 13/64 K.FAALDNEEEDK[136.11]EEEIIK[136.11].E "sp|Q8NE71|ABCF1_HUMAN,tr|Q5STZ8|Q5STZ8_HUMAN,tr|A0A0G2JJB9|A0A0G2JJB9_HUMAN" 3 2036.9761 0.71 68000 16612 3 2036.980575 679.9993 ATP-binding cassette sub-family F member 1 OS=Homo sapiens OX=9606 GN=ABCF1 PE=1 SV=2 3.94 2886.9 - 233018 - - - 2.1984 - 2.641 0.559 - 169.4 1 2 1 0.0045 17 0 0 0 2.43E+06 3.40E+06 - - - 7.2245 0.9908 221125_WJC_METTL3_EV_vs_WT_F05.16614.16614.4 0.00059 13/72 R.EKLTLLHYDPVVK.Q sp|O75394|RM33_HUMAN 1 1553.8817 1.16 68002 16614 4 1553.882544 389.4777 "39S ribosomal protein L33, mitochondrial OS=Homo sapiens OX=9606 GN=MRPL33 PE=1 SV=1" 6.85 2887.1 - 218475 - - - 0.5238 - 2.179 0.252 - 132.1 1 2 1 0.0008 13 0 0 0 4.22E+06 3.63E+06 - - - 1.708 1 221125_WJC_METTL3_EV_vs_WT_F05.16615.16615.2 2.52E-10 30-Oct K.C[160.03]SVC[160.03]PDYDLC[160.03]SVC[160.03]EGK[136.11].G "sp|Q13501|SQSTM_HUMAN,tr|E3W990|E3W990_HUMAN,tr|E9PFW8|E9PFW8_HUMAN,tr|E7EMC7|E7EMC7_HUMAN,tr|C9JRJ8|C9JRJ8_HUMAN" 5 1955.7613 2.09 68003 16615 2 1956.757962 978.8879 Sequestosome-1 OS=Homo sapiens OX=9606 GN=SQSTM1 PE=1 SV=1 4.03 2887.3 - 216846 - - - 509.6 - 2.057 0.727 - 219.1 1 2 0 0.9967 16 0 0 0 5.38E+06 2.58E+06 - - - 5.8709 0.9871 221125_WJC_METTL3_EV_vs_WT_F05.16616.16616.3 0.0703 Jul-36 K.TWFDKPNFNR.T "sp|Q5T8P6|RBM26_HUMAN,tr|A0A087X0H9|A0A087X0H9_HUMAN" 2 1323.636 0.33 68004 16616 3 1323.637359 442.2193 RNA-binding protein 26 OS=Homo sapiens OX=9606 GN=RBM26 PE=1 SV=3 8.41 2887.4 - 170518 - - - 1.0116 - 1.341 0.208 - 53.6 1 2 0 0.0013 10 0 0 0 1.03E+06 3.16E+06 - - - 1.7155 0.9999 221125_WJC_METTL3_EV_vs_WT_F05.16621.16621.3 1.42E-05 18/48 K.NREPVQLETLSIR.G "sp|P62314|SMD1_HUMAN,tr|J3QLI9|J3QLI9_HUMAN" 2 1553.8526 2 68007 16621 3 1553.851197 518.9581 Small nuclear ribonucleoprotein Sm D1 OS=Homo sapiens OX=9606 GN=SNRPD1 PE=1 SV=1 6.14 2887.9 - 2.82E+06 - - - -0.874 - 3.638 0.529 - 824 1 2 1 -0.0014 13 0 0 0 5.26E+07 2.63E+07 - - - 7.9389 1 221125_WJC_METTL3_EV_vs_WT_F05.16622.16622.3 1.31E-05 16/48 R.DLNYC[160.03]FSGMSDHR.Y "sp|P55795|HNRH2_HUMAN,sp|P31943|HNRH1_HUMAN,tr|H0YBD7|H0YBD7_HUMAN,tr|H0YB39|H0YB39_HUMAN,tr|H0YBG7|H0YBG7_HUMAN,tr|E9PCY7|E9PCY7_HUMAN,tr|G8JLB6|G8JLB6_HUMAN" 7 1600.6399 1.09 68008 16622 3 1600.641404 534.5539 Heterogeneous nuclear ribonucleoprotein H2 OS=Homo sapiens OX=9606 GN=HNRNPH2 PE=1 SV=1 5.21 2888 - 2.19E+06 - - - 0.9634 - 2.634 0.688 - 245.3 1 2 0 0.0015 13 0 0 0 1.63E+08 1.50E+08 - - - 8.836 1 221125_WJC_METTL3_EV_vs_WT_F05.16624.16624.2 2.00E-07 18/26 K.LGKDAVEDLESVGK.G sp|P81605|DCD_HUMAN 1 1458.7566 999 68010 16624 2 1458.75727 730.3856 Dermcidin OS=Homo sapiens OX=9606 GN=DCD PE=1 SV=2 4.32 2888.2 - 1.59E+06 - - - 0.4668 - 3.359 0.564 - 870.4 1 2 1 0.0007 14 0 0 0 5.32E+07 0.00E+00 - - - 6.247 0.9998 221125_WJC_METTL3_EV_vs_WT_F05.16626.16626.3 0.00408 14/40 R.NDEELNKLLGK.V "sp|Q9BTM1|H2AJ_HUMAN,sp|Q99878|H2A1J_HUMAN,sp|Q16777|H2A2C_HUMAN,sp|P20671|H2A1D_HUMAN,sp|P0C0S8|H2A1_HUMAN,sp|Q6FI13|H2A2A_HUMAN,sp|Q96KK5|H2A1H_HUMAN,tr|A0A0U1RR32|A0A0U1RR32_HUMAN,tr|A0A0U1RRH7|A0A0U1RRH7_HUMAN,tr|H0YFX9|H0YFX9_HUMAN" 10 1271.6721 1.24 68012 16626 3 1271.671932 424.898 Histone H2A.J OS=Homo sapiens OX=9606 GN=H2AJ PE=1 SV=1 4.68 2888.4 - 711640 - - - -0.1565 - 2.348 0.472 - 379.8 1 2 1 -0.0002 11 0 0 0 1.57E+08 1.27E+08 - - - 6.2271 0.9999 221125_WJC_METTL3_EV_vs_WT_F05.16629.16629.3 4.89E-07 18/52 R.ETLEEYNKEFAEVK.N "sp|Q13948|CASP_HUMAN,sp|P39880|CUX1_HUMAN,tr|A0A2R8Y852|A0A2R8Y852_HUMAN,tr|A0A2R8YDI1|A0A2R8YDI1_HUMAN" 4 1727.8254 1.05 68015 16629 3 1727.826058 576.9491 Protein CASP OS=Homo sapiens OX=9606 GN=CUX1 PE=1 SV=2 4.33 2888.8 - 670422 - - - 0.3826 - 3.338 0.56 - 588.4 1 2 1 0.0007 14 0 0 0 9.62E+06 9.16E+06 - - - 7.9866 0.9999 221125_WJC_METTL3_EV_vs_WT_F05.16630.16630.3 1.83E-09 15/52 R.ETLEEYNK[136.11]EFAEVK[136.11].N "sp|Q13948|CASP_HUMAN,sp|P39880|CUX1_HUMAN,tr|A0A2R8Y852|A0A2R8Y852_HUMAN,tr|A0A2R8YDI1|A0A2R8YDI1_HUMAN" 4 1743.8538 0.99 68016 16630 3 1743.855317 582.2919 Protein CASP OS=Homo sapiens OX=9606 GN=CUX1 PE=1 SV=2 4.33 2888.9 - 549542 - - - 0.8716 - 3.105 0.555 - 345.7 1 2 1 0.0015 14 0 0 0 9.62E+06 9.74E+06 - - - 7.7383 0.9975 221125_WJC_METTL3_EV_vs_WT_F05.16631.16631.3 0.00131 Aug-44 R.EGKEWETVLTSR.L sp|P54198|HIRA_HUMAN 1 1433.7151 1.58 68017 16631 3 1433.716273 478.9123 Protein HIRA OS=Homo sapiens OX=9606 GN=HIRA PE=1 SV=2 4.79 2889 - 433411 - - - 0.8474 - 1.759 0.33 - 101.8 1 2 1 0.0012 12 0 0 0 4.95E+06 3.14E+06 - - - 3.7842 0.9997 221125_WJC_METTL3_EV_vs_WT_F05.16632.16632.2 0.00012 28-Aug R.TSSAVWNSPPLQGAR.V sp|Q9NQS7|INCE_HUMAN 1 1569.79 0.82 68018 16632 2 1569.791035 785.9023 Inner centromere protein OS=Homo sapiens OX=9606 GN=INCENP PE=1 SV=3 9.41 2889.2 - 153337 - - - 0.688 - 1.846 0.42 - 136.5 1 2 0 0.0011 15 0 0 0 1.28E+06 1.57E+06 - - - 3.6499 0.9984 221125_WJC_METTL3_EV_vs_WT_F05.16634.16634.2 0.0159 Sep-32 K.EKPDSVDGQQPLVNGVP.- "sp|Q06787|FMR1_HUMAN,tr|A8MQB8|A8MQB8_HUMAN,tr|G3V0J0|G3V0J0_HUMAN" 3 1777.8846 2.27 68019 16634 2 1777.884403 889.9496 Synaptic functional regulator FMR1 OS=Homo sapiens OX=9606 GN=FMR1 PE=1 SV=1 4.03 2889.4 - 1.20E+06 - - - -0.135 - 1.554 0.252 - 156.1 1 2 0 -0.0002 17 0 0 0 1.36E+08 5.99E+07 - - - 1.986 1 221125_WJC_METTL3_EV_vs_WT_F05.16636.16636.3 1.17E-08 16/48 R.DLNYC[160.03]FSGMSDHR[166.11].Y "sp|P55795|HNRH2_HUMAN,sp|P31943|HNRH1_HUMAN,tr|H0YBD7|H0YBD7_HUMAN,tr|H0YB39|H0YB39_HUMAN,tr|H0YBG7|H0YBG7_HUMAN,tr|E9PCY7|E9PCY7_HUMAN,tr|G8JLB6|G8JLB6_HUMAN" 7 1610.6481 1.08 68020 16636 3 1610.648746 537.89 Heterogeneous nuclear ribonucleoprotein H2 OS=Homo sapiens OX=9606 GN=HNRNPH2 PE=1 SV=1 5.21 2889.6 - 8.02E+06 - - - 0.3812 - 2.387 0.654 - 284 1 2 0 0.0006 13 0 0 0 1.63E+08 1.50E+08 - - - 8.1902 1 221125_WJC_METTL3_EV_vs_WT_F05.16639.16639.3 7.09E-10 14/56 R.KTDFFIGGEEGMAEK.L "sp|Q9Y266|NUDC_HUMAN,tr|A0A0A0MSU9|A0A0A0MSU9_HUMAN" 2 1657.7658 1.79 68023 16639 3 1657.763663 553.5959 Nuclear migration protein nudC OS=Homo sapiens OX=9606 GN=NUDC PE=1 SV=1 4.41 2889.8 - 1.51E+06 - - - -1.2728 - 2.79 0.643 - 318 1 2 0 -0.0021 15 0 0 0 1.93E+07 1.08E+07 - - - 8.3855 1 221125_WJC_METTL3_EV_vs_WT_F05.16641.16641.3 4.25E-10 16/56 K.DVDAAYMNKVELEAK.V "sp|P13647|K2C5_HUMAN,sp|O95678|K2C75_HUMAN,tr|H0YIN9|H0YIN9_HUMAN" 3 1694.8185 0.86 68025 16641 3 1694.818373 565.9468 "Keratin, type II cytoskeletal 5 OS=Homo sapiens OX=9606 GN=KRT5 PE=1 SV=3" 4.32 2889.9 - 1.33E+06 - - - -0.0968 - 3.126 0.678 - 191.7 1 2 1 -0.0002 15 0 0 0 9.57E+06 1.11E+07 - - - 9.073 1 221125_WJC_METTL3_EV_vs_WT_F05.16642.16642.3 1.43E-11 23/80 K.GEAVLRPGLDAEPELSPEEQR.V "sp|Q9BRJ6|CG050_HUMAN,tr|C9JQV0|C9JQV0_HUMAN,tr|H7C2R9|H7C2R9_HUMAN,tr|H7C0T1|H7C0T1_HUMAN" 4 2291.1394 2.06 68026 16642 3 2291.139896 764.7204 Uncharacterized protein C7orf50 OS=Homo sapiens OX=9606 GN=C7orf50 PE=1 SV=1 4.14 2890.1 - 1.03E+06 - - - 0.2366 - 4.206 0.646 - 589.5 1 2 0 0.0005 21 0 0 0 1.03E+07 4.97E+06 - - - 9.1861 1 221125_WJC_METTL3_EV_vs_WT_F05.16643.16643.3 4.73E-08 15/56 R.K[136.11]TDFFIGGEEGMAEK[136.11].L "sp|Q9Y266|NUDC_HUMAN,tr|A0A0A0MSU9|A0A0A0MSU9_HUMAN" 2 1673.7942 1.79 68027 16643 3 1673.79544 558.9387 Nuclear migration protein nudC OS=Homo sapiens OX=9606 GN=NUDC PE=1 SV=1 4.41 2890.2 - 969218 - - - 0.757 - 2.986 0.569 - 357.7 1 2 0 0.0013 15 0 0 0 1.93E+07 1.08E+07 - - - 7.7379 0.9761 221125_WJC_METTL3_EV_vs_WT_F05.16645.16645.4 0.205 Oct-84 R.TFYPHHPQMLGFDPR[166.11].W sp|Q5JSZ5|PRC2B_HUMAN 1 1851.8754 1.63 68029 16645 4 1851.875748 463.9761 Protein PRRC2B OS=Homo sapiens OX=9606 GN=PRRC2B PE=1 SV=2 6.61 2890.4 - 721941 - - - 0.1723 - 1.924 0.188 - 43.8 2 2 0 0.0003 15 0 0 0 1.70E+07 1.04E+07 - - - 0.867 1 221125_WJC_METTL3_EV_vs_WT_F05.16647.16647.2 2.11E-05 15/20 R.NDEELNK[136.11]LLGK[136.11].V "sp|Q9BTM1|H2AJ_HUMAN,sp|Q99878|H2A1J_HUMAN,sp|Q16777|H2A2C_HUMAN,sp|P20671|H2A1D_HUMAN,sp|P0C0S8|H2A1_HUMAN,sp|Q6FI13|H2A2A_HUMAN,sp|Q96KK5|H2A1H_HUMAN,tr|A0A0U1RR32|A0A0U1RR32_HUMAN,tr|A0A0U1RRH7|A0A0U1RRH7_HUMAN,tr|H0YFX9|H0YFX9_HUMAN" 10 1287.7005 1.18 68031 16647 2 1287.700742 644.8575 Histone H2A.J OS=Homo sapiens OX=9606 GN=H2AJ PE=1 SV=1 4.68 2890.6 - 619433 - - - 0.1639 - 3.413 0.615 - 995.9 1 2 1 0.0002 11 0 0 0 2.95E+07 2.50E+07 - - - 6.9042 0.9998 221125_WJC_METTL3_EV_vs_WT_F05.16648.16648.3 6.37E-06 19/52 K.EIEIDIEPTDK[136.11]VER[166.11].L "sp|Q15843|NEDD8_HUMAN,tr|E9PS38|E9PS38_HUMAN,tr|S4R3E9|S4R3E9_HUMAN,tr|E9PL57|E9PL57_HUMAN,tr|F8VSA6|F8VSA6_HUMAN" 5 1702.8744 1.45 68032 16648 3 1702.877304 568.6321 NEDD8 OS=Homo sapiens OX=9606 GN=NEDD8 PE=1 SV=1 4.08 2890.7 - 617138 - - - 1.696 - 2.904 0.456 - 452.5 1 2 1 0.0029 14 0 0 0 4.61E+07 3.17E+07 - - - 6.4563 1 221125_WJC_METTL3_EV_vs_WT_F05.16650.16650.2 2.11E-06 16/30 R.KVIGIEC[160.03]SSISDYAVK.L "sp|Q99873|ANM1_HUMAN,tr|E9PQ98|E9PQ98_HUMAN,tr|E9PKG1|E9PKG1_HUMAN,tr|E9PNR9|E9PNR9_HUMAN,tr|H0YDE4|H0YDE4_HUMAN,tr|E9PMW9|E9PMW9_HUMAN,tr|E9PIX6|E9PIX6_HUMAN" 7 1767.9077 3.84 68034 16650 2 1767.908711 884.9611 Protein arginine N-methyltransferase 1 OS=Homo sapiens OX=9606 GN=PRMT1 PE=1 SV=3 6.06 2891 - 487509 - - - 0.5792 - 3.362 0.634 - 772.4 1 2 0 0.001 16 0 0 0 2.40E+06 6.25E+05 - - - 6.7045 1 221125_WJC_METTL3_EV_vs_WT_F05.16654.16654.2 4.68E-09 Dec-32 R.SGGGFSSGSAGIINYQR.R sp|P04264|K2C1_HUMAN 1 1656.7856 999 68037 16654 2 1656.78481 829.4001 "Keratin, type II cytoskeletal 1 OS=Homo sapiens OX=9606 GN=KRT1 PE=1 SV=6" 8.46 2891.6 - 164698 - - - -0.4756 - 2.689 0.608 - 383.4 1 2 0 -0.0008 17 0 0 0 2.92E+07 0.00E+00 - - - 5.9634 0.9999 221125_WJC_METTL3_EV_vs_WT_F05.16656.16656.3 0.0114 18/52 K.EIEIDIEPTDKVER.L "sp|Q15843|NEDD8_HUMAN,tr|E9PS38|E9PS38_HUMAN,tr|S4R3E9|S4R3E9_HUMAN,tr|E9PL57|E9PL57_HUMAN,tr|F8VSA6|F8VSA6_HUMAN" 5 1684.8519 1.41 68038 16656 3 1684.850923 562.6246 NEDD8 OS=Homo sapiens OX=9606 GN=NEDD8 PE=1 SV=1 4.08 2891.8 - 1.98E+06 - - - -0.6072 - 3.201 0.476 - 449 1 2 1 -0.001 14 0 0 0 4.32E+07 3.07E+07 - - - 6.9386 1 221125_WJC_METTL3_EV_vs_WT_F05.16657.16657.2 0.000145 14/20 R.NDEELNKLLGK.V "sp|Q9BTM1|H2AJ_HUMAN,sp|Q99878|H2A1J_HUMAN,sp|Q16777|H2A2C_HUMAN,sp|P20671|H2A1D_HUMAN,sp|P0C0S8|H2A1_HUMAN,sp|Q6FI13|H2A2A_HUMAN,sp|Q96KK5|H2A1H_HUMAN,tr|A0A0U1RR32|A0A0U1RR32_HUMAN,tr|A0A0U1RRH7|A0A0U1RRH7_HUMAN,tr|H0YFX9|H0YFX9_HUMAN" 10 1271.6721 1.18 68039 16657 2 1271.67155 636.8433 Histone H2A.J OS=Homo sapiens OX=9606 GN=H2AJ PE=1 SV=1 4.68 2891.9 - 1.76E+06 - - - -0.4569 - 2.934 0.551 - 774.2 1 2 1 -0.0006 11 0 0 0 2.95E+07 2.50E+07 - - - 6.0223 0.9999 221125_WJC_METTL3_EV_vs_WT_F05.16658.16658.3 1.78E-05 14/40 R.NDEELNK[136.11]LLGK[136.11].V "sp|Q9BTM1|H2AJ_HUMAN,sp|Q99878|H2A1J_HUMAN,sp|Q16777|H2A2C_HUMAN,sp|P20671|H2A1D_HUMAN,sp|P0C0S8|H2A1_HUMAN,sp|Q6FI13|H2A2A_HUMAN,sp|Q96KK5|H2A1H_HUMAN,tr|A0A0U1RR32|A0A0U1RR32_HUMAN,tr|A0A0U1RRH7|A0A0U1RRH7_HUMAN,tr|H0YFX9|H0YFX9_HUMAN" 10 1287.7005 1.24 68040 16658 3 1287.700035 430.2408 Histone H2A.J OS=Homo sapiens OX=9606 GN=H2AJ PE=1 SV=1 4.68 2892 - 1.03E+07 - - - -0.3852 - 2.6 0.533 - 322.6 1 2 1 -0.0005 11 0 0 0 1.57E+08 1.27E+08 - - - 7.1967 0.9993 221125_WJC_METTL3_EV_vs_WT_F05.16659.16659.3 9.31E-06 14/60 K.DVYVDSK[136.11]DPVSSLQVK[136.11].A sp|Q9P032|NDUF4_HUMAN 1 1793.9382 1.69 68041 16659 3 1793.943217 598.9867 NADH dehydrogenase [ubiquinone] 1 alpha subcomplex assembly factor 4 OS=Homo sapiens OX=9606 GN=NDUFAF4 PE=1 SV=1 4.43 2892 - 3.97E+06 - - - 2.7994 - 2.236 0.488 - 178.3 1 2 1 0.005 16 0 0 0 6.96E+07 4.13E+07 - - - 6.044 1 221125_WJC_METTL3_EV_vs_WT_F05.16660.16660.2 5.65E-09 13/24 R.DLNYC[160.03]FSGMSDHR[166.11].Y "sp|P55795|HNRH2_HUMAN,sp|P31943|HNRH1_HUMAN,tr|H0YBD7|H0YBD7_HUMAN,tr|H0YB39|H0YB39_HUMAN,tr|H0YBG7|H0YBG7_HUMAN,tr|E9PCY7|E9PCY7_HUMAN,tr|G8JLB6|G8JLB6_HUMAN" 7 1610.6481 1.15 68042 16660 2 1610.646722 806.3313 Heterogeneous nuclear ribonucleoprotein H2 OS=Homo sapiens OX=9606 GN=HNRNPH2 PE=1 SV=1 5.21 2892.1 - 1.21E+06 - - - -0.8754 - 2.734 0.686 - 541.5 1 2 0 -0.0014 13 0 0 0 1.08E+07 9.39E+06 - - - 6.6887 1 221125_WJC_METTL3_EV_vs_WT_F05.16661.16661.2 4.54E-05 15/24 R.DLNYC[160.03]FSGMSDHR.Y "sp|P55795|HNRH2_HUMAN,sp|P31943|HNRH1_HUMAN,tr|H0YBD7|H0YBD7_HUMAN,tr|H0YB39|H0YB39_HUMAN,tr|H0YBG7|H0YBG7_HUMAN,tr|E9PCY7|E9PCY7_HUMAN,tr|G8JLB6|G8JLB6_HUMAN" 7 1600.6399 1.15 68043 16661 2 1600.639606 801.3272 Heterogeneous nuclear ribonucleoprotein H2 OS=Homo sapiens OX=9606 GN=HNRNPH2 PE=1 SV=1 5.21 2892.3 - 1.04E+06 - - - -0.1599 - 3.056 0.677 - 835.2 1 2 0 -0.0003 13 0 0 0 1.08E+07 9.39E+06 - - - 6.9083 1 221125_WJC_METTL3_EV_vs_WT_F05.16662.16662.3 3.85E-09 17/48 R.EHQISPGDFPSLR[166.11].K "sp|Q9H4M9|EHD1_HUMAN,tr|C9JC03|C9JC03_HUMAN,tr|C9J2Z4|C9J2Z4_HUMAN,tr|A0A024R571|A0A024R571_HUMAN" 4 1491.7346 1.47 68044 16662 3 1491.737242 498.2521 EH domain-containing protein 1 OS=Homo sapiens OX=9606 GN=EHD1 PE=1 SV=2 5.32 2892.4 - 977306 - - - 1.7966 - 3.052 0.613 - 401.5 1 2 0 0.0027 13 0 0 0 2.06E+07 1.40E+07 - - - 8.3989 1 221125_WJC_METTL3_EV_vs_WT_F05.16663.16663.3 4.34E-10 24/80 K.GEAVLR[166.11]PGLDAEPELSPEEQR[166.11].V "sp|Q9BRJ6|CG050_HUMAN,tr|C9JQV0|C9JQV0_HUMAN,tr|H7C2R9|H7C2R9_HUMAN,tr|H7C0T1|H7C0T1_HUMAN" 4 2311.1559 2.06 68045 16663 3 2311.151771 771.3926 Uncharacterized protein C7orf50 OS=Homo sapiens OX=9606 GN=C7orf50 PE=1 SV=1 4.14 2892.5 - 712480 - - - -1.784 - 4.1 0.642 - 570.2 1 2 0 -0.0041 21 0 0 0 1.03E+07 4.97E+06 - - - 9.0793 0.9999 221125_WJC_METTL3_EV_vs_WT_F05.16669.16669.3 4.83E-06 13/44 K.GNSLFAEVEDR[166.11]R[166.11].A "sp|Q96EA4|SPDLY_HUMAN,tr|H0YBG5|H0YBG5_HUMAN" 2 1411.6959 0.42 68051 16669 3 1411.697551 471.5726 Protein Spindly OS=Homo sapiens OX=9606 GN=SPDL1 PE=1 SV=2 4.68 2893.3 - 302679 - - - 1.183 - 2.287 0.468 - 303.4 1 2 0 0.0017 12 0 0 0 9.89E+05 2.33E+06 - - - 6.0503 0.9998 221125_WJC_METTL3_EV_vs_WT_F05.16672.16672.2 2.92E-05 Jul-32 R.NVSSFPDDATSPLQENR[166.11].N "sp|P52292|IMA1_HUMAN,tr|J3QLL0|J3QLL0_HUMAN,tr|J3KS65|J3KS65_HUMAN,tr|A0A7I2V3Z3|A0A7I2V3Z3_HUMAN,tr|A0A7I2YQE1|A0A7I2YQE1_HUMAN,tr|A0A7I2V487|A0A7I2V487_HUMAN,tr|A0A7I2V351|A0A7I2V351_HUMAN" 7 1885.8682 -1 68054 16672 2 1885.869493 943.9414 Importin subunit alpha-1 OS=Homo sapiens OX=9606 GN=KPNA2 PE=1 SV=1 4.03 2893.7 - 210502 - - - 0.7095 - 1.668 0.573 - 95 1 2 0 0.0013 17 0 0 0 0.00E+00 0.00E+00 - - - 4.5306 0.9991 221125_WJC_METTL3_EV_vs_WT_F05.16675.16675.2 0.00608 28-Aug R.TSSAVWNSPPLQGAR[166.11].V sp|Q9NQS7|INCE_HUMAN 1 1579.7982 3.23 68057 16675 2 1579.796791 790.9064 Inner centromere protein OS=Homo sapiens OX=9606 GN=INCENP PE=1 SV=3 9.41 2894.1 - 153296 - - - -0.9077 - 1.621 0.327 - 166.4 1 2 0 -0.0014 15 0 0 0 2.40E+06 7.43E+05 - - - 2.6434 1 221125_WJC_METTL3_EV_vs_WT_F05.16677.16677.3 0.00222 21/56 K.R[166.11]PPESPPIVEEWNSR[166.11].A "sp|Q9BTL3|RAMAC_HUMAN,tr|A0A3B3IU46|A0A3B3IU46_HUMAN" 2 1811.9069 1.28 68058 16677 3 1811.906918 604.9763 RNA guanine-N7 methyltransferase activating subunit OS=Homo sapiens OX=9606 GN=RAMAC PE=1 SV=1 4.79 2894.3 - 779131 - - - -0.0105 - 3.405 0.509 - 764.9 1 2 0 0 15 0 0 0 1.38E+07 1.08E+07 - - - 7.412 0.8622 221125_WJC_METTL3_EV_vs_WT_F05.16678.16678.4 0.266 Oct-90 K.WAEKPAFGTPLEEHLK.R sp|Q68EM7|RHG17_HUMAN 1 1851.9519 0.73 68059 16678 4 1851.952521 463.9953 Rho GTPase-activating protein 17 OS=Homo sapiens OX=9606 GN=ARHGAP17 PE=1 SV=1 5.5 2894.4 - 862349 - - - 0.3164 - 1.545 0.103 - 53.9 1 2 0 0.0006 16 0 0 0 6.39E+06 8.70E+06 - - - 0.2756 1 221125_WJC_METTL3_EV_vs_WT_F05.16679.16679.3 4.84E-10 16/60 K.DVYVDSKDPVSSLQVK.A sp|Q9P032|NDUF4_HUMAN 1 1777.9098 1.69 68060 16679 3 1777.910147 593.6439 NADH dehydrogenase [ubiquinone] 1 alpha subcomplex assembly factor 4 OS=Homo sapiens OX=9606 GN=NDUFAF4 PE=1 SV=1 4.43 2894.5 - 6.66E+06 - - - 0.198 - 2.6 0.692 - 232 1 2 1 0.0004 16 0 0 0 7.06E+07 4.17E+07 - - - 8.7067 1 221125_WJC_METTL3_EV_vs_WT_F05.16680.16680.3 3.11E-09 17/48 R.EHQISPGDFPSLR.K "sp|Q9H4M9|EHD1_HUMAN,tr|C9JC03|C9JC03_HUMAN,tr|C9J2Z4|C9J2Z4_HUMAN,tr|A0A024R571|A0A024R571_HUMAN" 4 1481.7263 1.41 68061 16680 3 1481.72508 494.916 EH domain-containing protein 1 OS=Homo sapiens OX=9606 GN=EHD1 PE=1 SV=2 5.32 2894.5 - 1.40E+06 - - - -0.818 - 3.041 0.642 - 418.2 1 2 0 -0.0012 13 0 0 0 2.08E+07 1.48E+07 - - - 8.7128 1 221125_WJC_METTL3_EV_vs_WT_F05.16681.16681.3 1.93E-08 19/52 R.HFLQQATQVNAWDR.T sp|P37198|NUP62_HUMAN 1 1712.8383 1.68 68062 16681 3 1712.837363 571.9534 Nuclear pore glycoprotein p62 OS=Homo sapiens OX=9606 GN=NUP62 PE=1 SV=3 6.74 2894.6 - 1.18E+06 - - - -0.5482 - 3.572 0.605 - 866.4 1 2 0 -0.0009 14 0 0 0 3.43E+07 2.04E+07 - - - 8.6683 1 221125_WJC_METTL3_EV_vs_WT_F05.16682.16682.3 2.31E-06 18/52 R.HFLQQATQVNAWDR[166.11].T sp|P37198|NUP62_HUMAN 1 1722.8466 2.75 68063 16682 3 1722.842908 575.2895 Nuclear pore glycoprotein p62 OS=Homo sapiens OX=9606 GN=NUP62 PE=1 SV=3 6.74 2894.7 - 835340 - - - -2.1267 - 3.703 0.515 - 677.1 1 2 0 -0.0037 14 0 0 0 6.70E+07 2.44E+07 - - - 7.7598 1 221125_WJC_METTL3_EV_vs_WT_F05.16683.16683.3 2.04E-10 21/68 R.VQEAARPEEVVSQTPLLR.S "sp|Q9P1Y6|PHRF1_HUMAN,tr|A0A0J9YX88|A0A0J9YX88_HUMAN,tr|B7ZM65|B7ZM65_HUMAN,tr|A0A0J9YYB5|A0A0J9YYB5_HUMAN,tr|A0A0J9YWD5|A0A0J9YWD5_HUMAN,tr|F8WEF5|F8WEF5_HUMAN,tr|E9PJ24|E9PJ24_HUMAN" 7 2021.0906 2.4 68064 16683 3 2021.090908 674.7041 PHD and RING finger domain-containing protein 1 OS=Homo sapiens OX=9606 GN=PHRF1 PE=1 SV=3 4.79 2894.8 - 771307 - - - 0.1756 - 3.702 0.613 - 488.8 1 2 0 0.0004 18 0 0 0 8.89E+06 3.71E+06 - - - 8.6335 0.9993 221125_WJC_METTL3_EV_vs_WT_F05.16687.16687.3 0.000205 Nov-40 R.NDEELNKLLGK[136.11].V "sp|Q9BTM1|H2AJ_HUMAN,sp|Q99878|H2A1J_HUMAN,sp|Q16777|H2A2C_HUMAN,sp|P20671|H2A1D_HUMAN,sp|P0C0S8|H2A1_HUMAN,sp|Q6FI13|H2A2A_HUMAN,sp|Q96KK5|H2A1H_HUMAN,tr|A0A0U1RR32|A0A0U1RR32_HUMAN,tr|A0A0U1RRH7|A0A0U1RRH7_HUMAN,tr|H0YFX9|H0YFX9_HUMAN" 10 1279.6863 - 68068 16687 3 1279.68849 427.5694 Histone H2A.J OS=Homo sapiens OX=9606 GN=H2AJ PE=1 SV=1 4.68 2895.3 - 316183 - - - 1.6871 - 2.051 0.415 - 254.5 1 2 1 0.0022 11 0 0 0 - - - - - 5.2069 1 221125_WJC_METTL3_EV_vs_WT_F05.16695.16695.2 4.59E-12 17/36 A.AGSGAGGGGSAEQLDALVK.K sp|Q86SX6|GLRX5_HUMAN 1 1643.8115 1.76 68074 16695 2 1643.811412 822.913 "Glutaredoxin-related protein 5, mitochondrial OS=Homo sapiens OX=9606 GN=GLRX5 PE=1 SV=2" 4.37 2896.4 - 580054 - - - -0.0402 - 3.73 0.669 - 1068.4 1 1 0 -0.0001 19 0 0 0 4.76E+06 2.71E+06 - - - 7.2187 1 221125_WJC_METTL3_EV_vs_WT_F05.16696.16696.2 1.20E-07 Dec-32 K.VSYIPDEQIAQGPENGR.R sp|Q9NZI8|IF2B1_HUMAN 1 1871.9014 2 68075 16696 2 1871.901565 936.958 Insulin-like growth factor 2 mRNA-binding protein 1 OS=Homo sapiens OX=9606 GN=IGF2BP1 PE=1 SV=2 4.14 2896.5 - 573302 - - - 0.1117 - 2.331 0.651 - 179.3 1 2 0 0.0002 17 0 0 0 5.76E+07 2.88E+07 - - - 5.9299 0.9925 221125_WJC_METTL3_EV_vs_WT_F05.16697.16697.3 0.202 Sep-48 K.ASLASLPPLHVAK.L "sp|Q14203|DCTN1_HUMAN,tr|A0A804CDA6|A0A804CDA6_HUMAN,tr|E7EX90|E7EX90_HUMAN,tr|A0A7P0Z4C3|A0A7P0Z4C3_HUMAN,tr|E7EWF7|E7EWF7_HUMAN" 5 1302.766 2.28 68076 16697 3 1302.765706 435.2626 Dynactin subunit 1 OS=Homo sapiens OX=9606 GN=DCTN1 PE=1 SV=3 8.8 2896.7 - 450055 - - - -0.2042 - 1.544 0.203 - 136.1 1 2 0 -0.0003 13 0 0 0 5.05E+06 2.21E+06 - - - 1.9809 1 221125_WJC_METTL3_EV_vs_WT_F05.16700.16700.2 3.08E-08 28-Dec R.IQFDEGYDNYPGQEK.T sp|Q92665|RT31_HUMAN 1 1801.7795 2.44 68079 16700 2 1801.779565 901.897 "28S ribosomal protein S31, mitochondrial OS=Homo sapiens OX=9606 GN=MRPS31 PE=1 SV=3" 3.92 2897.1 - 350855 - - - 0.0311 - 2.554 0.674 - 282.1 1 2 0 0.0001 15 0 0 0 5.02E+06 2.06E+06 - - - 6.3244 1 221125_WJC_METTL3_EV_vs_WT_F05.16701.16701.2 1.39E-13 15/36 A.AGSGAGGGGSAEQLDALVK[136.11].K sp|Q86SX6|GLRX5_HUMAN 1 1651.8257 1.76 68080 16701 2 1651.826011 826.9201 "Glutaredoxin-related protein 5, mitochondrial OS=Homo sapiens OX=9606 GN=GLRX5 PE=1 SV=2" 4.37 2897.2 - 334446 - - - 0.2016 - 3.467 0.735 - 739.4 1 1 0 0.0003 19 0 0 0 4.76E+06 2.71E+06 - - - 7.5263 0.9893 221125_WJC_METTL3_EV_vs_WT_F05.16702.16702.3 0.142 Oct-48 K.ASLASLPPLHVAK[136.11].L "sp|Q14203|DCTN1_HUMAN,tr|A0A804CDA6|A0A804CDA6_HUMAN,tr|E7EX90|E7EX90_HUMAN,tr|A0A7P0Z4C3|A0A7P0Z4C3_HUMAN,tr|E7EWF7|E7EWF7_HUMAN" 5 1310.7802 2.39 68081 16702 3 1310.778999 437.934 Dynactin subunit 1 OS=Homo sapiens OX=9606 GN=DCTN1 PE=1 SV=3 8.8 2897.3 - 302969 - - - -0.8949 - 1.498 0.191 - 118.6 1 2 0 -0.0012 13 0 0 0 5.05E+06 2.11E+06 - - - 1.7649 0.9975 221125_WJC_METTL3_EV_vs_WT_F05.16705.16705.2 0.00146 26-Oct K.EIEIDIEPTDKVER.L "sp|Q15843|NEDD8_HUMAN,tr|E9PS38|E9PS38_HUMAN,tr|S4R3E9|S4R3E9_HUMAN,tr|E9PL57|E9PL57_HUMAN,tr|F8VSA6|F8VSA6_HUMAN" 5 1684.8519 0.91 68084 16705 2 1684.854358 843.4332 NEDD8 OS=Homo sapiens OX=9606 GN=NEDD8 PE=1 SV=1 4.08 2897.7 - 242241 - - - 1.4316 - 2.413 0.462 - 238 1 2 1 0.0024 14 0 0 0 1.89E+06 2.07E+06 - - - 4.6631 1 221125_WJC_METTL3_EV_vs_WT_F05.16712.16712.2 1.88E-10 16/32 K.VSYIPDEQIAQGPENGR[166.11].R sp|Q9NZI8|IF2B1_HUMAN 1 1881.9096 2.3 68089 16712 2 1881.909286 941.9621 Insulin-like growth factor 2 mRNA-binding protein 1 OS=Homo sapiens OX=9606 GN=IGF2BP1 PE=1 SV=2 4.14 2898.6 - 1.13E+06 - - - -0.1807 - 2.742 0.711 - 566.7 1 2 0 -0.0003 17 0 0 0 6.63E+07 2.88E+07 - - - 6.7722 1 221125_WJC_METTL3_EV_vs_WT_F05.16715.16715.3 0.00024 Dec-40 R.K[136.11]EDWNEIDPIK[136.11].K sp|Q10471|GALT2_HUMAN 1 1401.7111 1.65 68092 16715 3 1401.710119 468.2443 Polypeptide N-acetylgalactosaminyltransferase 2 OS=Homo sapiens OX=9606 GN=GALNT2 PE=1 SV=1 4.32 2899 - 598270 - - - -0.697 - 2.663 0.487 - 309.9 1 2 0 -0.001 11 0 0 0 4.67E+07 2.83E+07 - - - 6.7518 1 221125_WJC_METTL3_EV_vs_WT_F05.16716.16716.3 1.14E-06 13/68 K.ISSSVDATTVTSQQC[160.03]VFR.D sp|Q5T3J3|LRIF1_HUMAN 1 1984.9524 1.62 68093 16716 3 1984.954574 662.6581 Ligand-dependent nuclear receptor-interacting factor 1 OS=Homo sapiens OX=9606 GN=LRIF1 PE=1 SV=1 5.83 2899.1 - 493937 - - - 1.0927 - 2.815 0.558 - 196.7 1 2 0 0.0022 18 0 0 0 2.97E+06 1.83E+06 - - - 7.3377 1 221125_WJC_METTL3_EV_vs_WT_F05.16717.16717.2 7.05E-09 18/26 R.HFLQQATQVNAWDR.T sp|P37198|NUP62_HUMAN 1 1712.8383 2.95 68094 16717 2 1712.841523 857.4264 Nuclear pore glycoprotein p62 OS=Homo sapiens OX=9606 GN=NUP62 PE=1 SV=3 6.74 2899.2 - 415771 - - - 1.8805 - 3.593 0.624 - 1137.5 1 2 0 0.0032 14 0 0 0 2.88E+06 9.79E+05 - - - 6.8584 0.9978 221125_WJC_METTL3_EV_vs_WT_F05.16718.16718.3 0.000184 Nov-48 R.SKQLEDELVSLQK.K "sp|P09493|TPM1_HUMAN,tr|A0A0S2Z4G6|A0A0S2Z4G6_HUMAN,tr|H0YKP3|H0YKP3_HUMAN,tr|A0A087WTJ7|A0A087WTJ7_HUMAN" 4 1515.8144 1.95 68095 16718 3 1515.817025 506.2788 Tropomyosin alpha-1 chain OS=Homo sapiens OX=9606 GN=TPM1 PE=1 SV=2 4.68 2899.3 - 326336 - - - 1.7067 - 1.991 0.345 - 157.8 1 2 1 0.0026 13 0 0 0 2.79E+06 1.43E+06 - - - 4.2528 1 221125_WJC_METTL3_EV_vs_WT_F05.16719.16719.2 4.10E-07 28-Dec R.IQFDEGYDNYPGQEK[136.11].T sp|Q92665|RT31_HUMAN 1 1809.7937 2.44 68096 16719 2 1809.797601 905.9041 "28S ribosomal protein S31, mitochondrial OS=Homo sapiens OX=9606 GN=MRPS31 PE=1 SV=3" 3.92 2899.5 - 294876 - - - 2.1505 - 2.527 0.644 - 282.2 1 2 0 0.0039 15 0 0 0 5.02E+06 2.06E+06 - - - 6.0755 1 221125_WJC_METTL3_EV_vs_WT_F05.16720.16720.3 4.87E-06 14/72 R.MAKPEEVLVVENDQGEVVR.E "sp|O14980|XPO1_HUMAN,tr|A0A7I2V488|A0A7I2V488_HUMAN,tr|A0A7I2V461|A0A7I2V461_HUMAN,tr|A0A7I2V2H0|A0A7I2V2H0_HUMAN,tr|A0A7I2V3N0|A0A7I2V3N0_HUMAN,tr|A0A7I2V4A3|A0A7I2V4A3_HUMAN,tr|A0A7I2V3W6|A0A7I2V3W6_HUMAN,tr|A0A7I2YQV4|A0A7I2YQV4_HUMAN,tr|A0A7I2YQX3|A0A7I2YQX3_HUMAN,tr|A0A7I2V2Y6|A0A7I2V2Y6_HUMAN,tr|A0A7I2V6B9|A0A7I2V6B9_HUMAN,tr|A0A7I2V3P3|A0A7I2V3P3_HUMAN,tr|A0A7I2V2S3|A0A7I2V2S3_HUMAN" 13 2140.0834 0.92 68097 16720 3 2140.086374 714.3684 Exportin-1 OS=Homo sapiens OX=9606 GN=XPO1 PE=1 SV=1 4.25 2899.6 - 277110 - - - 1.3808 - 3.189 0.529 - 285 1 2 0 0.003 19 0 0 0 2.10E+06 2.28E+06 - - - 7.2862 1 221125_WJC_METTL3_EV_vs_WT_F05.16723.16723.2 2.83E-07 Nov-32 K.ISYIPDEEVSSPSPPQR.A "sp|Q9Y6M1|IF2B2_HUMAN,tr|F8W930|F8W930_HUMAN" 2 1899.9214 3.19 68100 16723 2 1899.922032 950.968 Insulin-like growth factor 2 mRNA-binding protein 2 OS=Homo sapiens OX=9606 GN=IGF2BP2 PE=1 SV=2 4.14 2900 - 261149 - - - 0.3211 - 2.319 0.659 - 222.1 1 2 0 0.0006 17 0 0 0 2.38E+07 7.44E+06 - - - 5.9762 0.9993 221125_WJC_METTL3_EV_vs_WT_F05.16724.16724.2 1.32E-05 13/26 R.HFLQQATQVNAWDR[166.11].T sp|P37198|NUP62_HUMAN 1 1722.8466 2.78 68101 16724 2 1722.852515 862.4306 Nuclear pore glycoprotein p62 OS=Homo sapiens OX=9606 GN=NUP62 PE=1 SV=3 6.74 2900.1 - 230690 - - - 3.4495 - 2.744 0.477 - 448.3 1 2 0 0.0059 14 0 0 0 3.39E+06 1.22E+06 - - - 5.0953 0.9995 221125_WJC_METTL3_EV_vs_WT_F05.16725.16725.3 3.02E-05 13/44 R.LLRDYQELMNTK.L sp|P04264|K2C1_HUMAN 1 1522.7814 1.64 68102 16725 3 1522.785628 508.6011 "Keratin, type II cytoskeletal 1 OS=Homo sapiens OX=9606 GN=KRT1 PE=1 SV=6" 6.07 2900.3 - 215251 - - - 2.8001 - 2.501 0.489 - 176.6 1 2 1 0.0043 12 0 0 0 5.10E+06 3.11E+06 - - - 6.5316 1 221125_WJC_METTL3_EV_vs_WT_F05.16726.16726.2 5.57E-07 13/34 K.ISSSVDATTVTSQQC[160.03]VFR.D sp|Q5T3J3|LRIF1_HUMAN 1 1984.9524 1.56 68103 16726 2 1984.953053 993.4835 Ligand-dependent nuclear receptor-interacting factor 1 OS=Homo sapiens OX=9606 GN=LRIF1 PE=1 SV=1 5.83 2900.4 - 215169 - - - 0.3265 - 2.664 0.629 - 425.9 1 2 0 0.0006 18 0 0 0 2.30E+06 1.47E+06 - - - 6.0955 1 221125_WJC_METTL3_EV_vs_WT_F05.16729.16729.3 7.45E-08 14/40 R.KEDWNEIDPIK.K sp|Q10471|GALT2_HUMAN 1 1385.6827 1.65 68104 16729 3 1385.683731 462.9015 Polypeptide N-acetylgalactosaminyltransferase 2 OS=Homo sapiens OX=9606 GN=GALNT2 PE=1 SV=1 4.32 2900.8 - 2.16E+06 - - - 0.7469 - 2.527 0.547 - 309.4 1 2 0 0.001 11 0 0 0 4.67E+07 2.83E+07 - - - 7.2718 1 221125_WJC_METTL3_EV_vs_WT_F05.16730.16730.3 9.27E-14 28/76 R.VPFSPGPAPPPHMGELDQER.L "sp|Q6Y7W6|GGYF2_HUMAN,tr|A0A7I2V3H7|A0A7I2V3H7_HUMAN,tr|I1E4Y6|I1E4Y6_HUMAN,tr|A0A7I2V516|A0A7I2V516_HUMAN,tr|A0A7I2V3H0|A0A7I2V3H0_HUMAN,tr|C9JHW1|C9JHW1_HUMAN,tr|A0A7I2V361|A0A7I2V361_HUMAN,tr|E7ESB6|E7ESB6_HUMAN" 8 2157.0313 4.38 68105 16730 3 2157.025538 720.0177 GRB10-interacting GYF protein 2 OS=Homo sapiens OX=9606 GN=GIGYF2 PE=1 SV=1 4.65 2901 - 884190 - - - -2.6824 - 4.876 0.609 - 1028.5 1 2 0 -0.0058 20 0 0 0 7.67E+07 1.75E+07 - - - 9.1718 1 221125_WJC_METTL3_EV_vs_WT_F05.16732.16732.3 7.67E-10 23/72 K.IPDPEAVKPDDWDEDAPAK.L "sp|P27824|CALX_HUMAN,tr|A0A7P0T937|A0A7P0T937_HUMAN,tr|A0A7P0T840|A0A7P0T840_HUMAN,tr|A0A7P0TB65|A0A7P0TB65_HUMAN,tr|A0A7P0TAE9|A0A7P0TAE9_HUMAN,tr|D6RGY2|D6RGY2_HUMAN,tr|A0A7P0T8G1|A0A7P0T8G1_HUMAN,tr|A0A7P0Z4D6|A0A7P0Z4D6_HUMAN,tr|A0A7P0Z484|A0A7P0Z484_HUMAN,tr|A0A7P0TAR9|A0A7P0TAR9_HUMAN,tr|A0A7P0T9L0|A0A7P0T9L0_HUMAN" 11 2106.9746 1.75 68107 16732 3 2106.976253 703.3321 Calnexin OS=Homo sapiens OX=9606 GN=CANX PE=1 SV=2 3.85 2901.1 - 1.12E+06 - - - 0.794 - 3.753 0.679 - 699.1 1 2 0 0.0017 19 0 0 0 3.23E+07 1.85E+07 - - - 9.359 1 221125_WJC_METTL3_EV_vs_WT_F05.16737.16737.2 4.94E-07 16/28 K.EGGQIAVFDATNTTR.E "sp|Q16875|F263_HUMAN,tr|A0A1W2PR17|A0A1W2PR17_HUMAN,tr|Q5W015|Q5W015_HUMAN,tr|A0A1W2PNV9|A0A1W2PNV9_HUMAN,tr|F2Z2I2|F2Z2I2_HUMAN,tr|Q5VX20|Q5VX20_HUMAN" 6 1578.7638 4.55 68112 16737 2 1578.760598 790.3892 "6-phosphofructo-2-kinase\fructose-2,6-bisphosphatase 3 OS=Homo sapiens OX=9606 GN=PFKFB3 PE=1 SV=1" 4.37 2901.8 - 569886 - - - -2.0275 - 2.98 0.628 - 842.6 1 2 0 -0.0032 15 0 0 0 3.73E+06 8.20E+05 - - - 6.3629 1 221125_WJC_METTL3_EV_vs_WT_F05.16738.16738.3 2.49E-07 19/68 K.LDNLDEEWATEHAC[160.03]QVSR.M sp|Q5SWX8|ODR4_HUMAN 1 2171.9542 0.9 68113 16738 3 2171.961215 724.992 Protein odr-4 homolog OS=Homo sapiens OX=9606 GN=ODR4 PE=1 SV=1 4.17 2901.9 - 512079 - - - 3.2317 - 3.83 0.592 - 634 1 2 0 0.007 18 0 0 0 2.47E+06 2.74E+06 - - - 8.4821 1 221125_WJC_METTL3_EV_vs_WT_F05.16740.16740.3 5.27E-08 17/60 R.RALEYTIYNQELNETR.A sp|Q9UQE7|SMC3_HUMAN 1 2011.9963 0.5 68115 16740 3 2011.993614 671.6727 Structural maintenance of chromosomes protein 3 OS=Homo sapiens OX=9606 GN=SMC3 PE=1 SV=2 4.79 2902.2 - 417798 - - - -1.3444 - 3.437 0.554 - 491.1 1 2 0 -0.0027 16 0 0 0 1.72E+06 3.47E+06 - - - 7.8836 1 221125_WJC_METTL3_EV_vs_WT_F05.16741.16741.3 3.43E-11 Dec-48 K.NHVC[160.03]QYYIYELQK[136.11].R "sp|Q9NTJ3|SMC4_HUMAN,tr|E9PD53|E9PD53_HUMAN,tr|C9JR83|C9JR83_HUMAN" 3 1764.8385 0.54 68116 16741 3 1764.842411 589.2868 Structural maintenance of chromosomes protein 4 OS=Homo sapiens OX=9606 GN=SMC4 PE=1 SV=2 6.74 2902.3 - 368978 - - - 2.2206 - 2.572 0.638 - 146.4 1 2 0 0.0039 13 0 0 0 1.35E+06 2.48E+06 - - - 8.2133 1 221125_WJC_METTL3_EV_vs_WT_F05.16744.16744.2 7.99E-07 15/20 R.KEDWNEIDPIK.K sp|Q10471|GALT2_HUMAN 1 1385.6827 1.54 68119 16744 2 1385.685263 693.8486 Polypeptide N-acetylgalactosaminyltransferase 2 OS=Homo sapiens OX=9606 GN=GALNT2 PE=1 SV=1 4.32 2902.7 - 298704 - - - 1.8525 - 3.133 0.58 - 880.7 1 2 0 0.0026 11 0 0 0 7.59E+06 4.92E+06 - - - 6.4134 0.9644 221125_WJC_METTL3_EV_vs_WT_F05.16746.16746.3 0.000228 Oct-40 R.HVNIDHLHVGW.Y "sp|O15372|EIF3H_HUMAN,tr|B3KS98|B3KS98_HUMAN,tr|A0A087WZK9|A0A087WZK9_HUMAN,tr|E5RFH0|E5RFH0_HUMAN,tr|E5RGU4|E5RGU4_HUMAN,tr|E5RJT0|E5RJT0_HUMAN" 6 1325.6629 - 68121 16746 3 1325.66617 442.8949 Eukaryotic translation initiation factor 3 subunit H OS=Homo sapiens OX=9606 GN=EIF3H PE=1 SV=1 6.25 2902.9 - 198806 - - - 2.4644 - 1.632 0.448 - 92.6 1 1 0 0.0033 11 0 0 0 - - - - - 4.9253 0.9999 221125_WJC_METTL3_EV_vs_WT_F05.16747.16747.2 1.61E-06 Aug-34 K.ISSSVDATTVTSQQC[160.03]VFR[166.11].D sp|Q5T3J3|LRIF1_HUMAN 1 1994.9607 1.56 68122 16747 2 1994.961367 998.4876 Ligand-dependent nuclear receptor-interacting factor 1 OS=Homo sapiens OX=9606 GN=LRIF1 PE=1 SV=1 5.83 2903.1 - 183315 - - - 0.3469 - 2.025 0.531 - 149.6 1 2 0 0.0007 18 0 0 0 2.30E+06 1.47E+06 - - - 4.6974 0.9998 221125_WJC_METTL3_EV_vs_WT_F05.16751.16751.2 9.13E-07 24-Nov R.TTPSYVAFTDTER[166.11].L "sp|P48741|HSP77_HUMAN,sp|P54652|HSP72_HUMAN,sp|P0DMV8|HS71A_HUMAN,sp|P34931|HS71L_HUMAN,sp|P11142|HSP7C_HUMAN,sp|P0DMV9|HS71B_HUMAN,sp|P17066|HSP76_HUMAN,tr|E9PQQ4|E9PQQ4_HUMAN,tr|E9PNE6|E9PNE6_HUMAN,tr|E9PKE3|E9PKE3_HUMAN,tr|E9PLF4|E9PLF4_HUMAN,tr|Q53FA3|Q53FA3_HUMAN,tr|E9PI65|E9PI65_HUMAN,tr|E9PK54|E9PK54_HUMAN,tr|E9PN25|E9PN25_HUMAN,tr|E9PPY6|E9PPY6_HUMAN,tr|E9PQK7|E9PQK7_HUMAN,tr|A0A0G2JIW1|A0A0G2JIW1_HUMAN" 18 1496.7023 0.14 68125 16751 2 1496.704969 749.3584 Putative heat shock 70 kDa protein 7 OS=Homo sapiens OX=9606 GN=HSPA7 PE=5 SV=2 4.37 2903.4 - 4.93E+06 - - - 1.8106 - 2.301 0.561 - 354.4 1 2 0 0.0027 13 0 0 0 1.83E+07 1.27E+08 - - - 5.3225 1 221125_WJC_METTL3_EV_vs_WT_F05.16752.16752.3 9.55E-08 16/56 K.RPPESPPIVEEWNSR.A "sp|Q9BTL3|RAMAC_HUMAN,tr|A0A3B3IU46|A0A3B3IU46_HUMAN" 2 1791.8904 1.39 68126 16752 3 1791.89343 598.3041 RNA guanine-N7 methyltransferase activating subunit OS=Homo sapiens OX=9606 GN=RAMAC PE=1 SV=1 4.79 2903.5 - 1.41E+06 - - - 1.6926 - 3.064 0.538 - 416.4 1 2 0 0.003 15 0 0 0 2.21E+07 1.59E+07 - - - 7.4591 0.9999 221125_WJC_METTL3_EV_vs_WT_F05.16754.16754.3 3.63E-07 14/48 R.K[136.11]EFSPFGSITSAK[136.11].V "sp|Q13310|PABP4_HUMAN,tr|A0A7I2V5W9|A0A7I2V5W9_HUMAN,tr|H0YEU6|H0YEU6_HUMAN,tr|B1ANR0|B1ANR0_HUMAN,tr|A0A7I2V4L7|A0A7I2V4L7_HUMAN,tr|A0A7I2V598|A0A7I2V598_HUMAN,tr|H0Y5F5|H0Y5F5_HUMAN" 7 1413.7475 0.15 68128 16754 3 1413.751957 472.2564 Polyadenylate-binding protein 4 OS=Homo sapiens OX=9606 GN=PABPC4 PE=1 SV=1 8.59 2903.7 - 792736 - - - 3.1661 - 2.588 0.522 - 251.7 1 2 0 0.0045 13 0 0 0 1.46E+07 9.63E+07 - - - 6.9367 0.9999 221125_WJC_METTL3_EV_vs_WT_F05.16755.16755.3 8.78E-06 Nov-48 R.TTPSYVAFTDTER[166.11].L "sp|P48741|HSP77_HUMAN,sp|P54652|HSP72_HUMAN,sp|P0DMV8|HS71A_HUMAN,sp|P34931|HS71L_HUMAN,sp|P11142|HSP7C_HUMAN,sp|P0DMV9|HS71B_HUMAN,sp|P17066|HSP76_HUMAN,tr|E9PQQ4|E9PQQ4_HUMAN,tr|E9PNE6|E9PNE6_HUMAN,tr|E9PKE3|E9PKE3_HUMAN,tr|E9PLF4|E9PLF4_HUMAN,tr|Q53FA3|Q53FA3_HUMAN,tr|E9PI65|E9PI65_HUMAN,tr|E9PK54|E9PK54_HUMAN,tr|E9PN25|E9PN25_HUMAN,tr|E9PPY6|E9PPY6_HUMAN,tr|E9PQK7|E9PQK7_HUMAN,tr|A0A0G2JIW1|A0A0G2JIW1_HUMAN" 18 1496.7023 0.17 68129 16755 3 1496.70509 499.908 Putative heat shock 70 kDa protein 7 OS=Homo sapiens OX=9606 GN=HSPA7 PE=5 SV=2 4.37 2903.8 - 700995 - - - 1.8915 - 2.034 0.46 - 120.1 1 2 0 0.0028 13 0 0 0 2.34E+06 1.34E+07 - - - 5.5928 0.9928 221125_WJC_METTL3_EV_vs_WT_F05.16756.16756.3 0.00313 Sep-60 R.EIIKQEESVDPDYWEK.L "sp|Q14839|CHD4_HUMAN,tr|A0A2R8Y4X2|A0A2R8Y4X2_HUMAN,tr|A0A2U3TZM0|A0A2U3TZM0_HUMAN,tr|A0A2R8Y5M9|A0A2R8Y5M9_HUMAN,tr|A0A2R8Y445|A0A2R8Y445_HUMAN,tr|A0A2R8YD40|A0A2R8YD40_HUMAN,tr|A0A2R8Y5J0|A0A2R8Y5J0_HUMAN,tr|A0A2R8Y425|A0A2R8Y425_HUMAN,tr|A0A2R8YFK9|A0A2R8YFK9_HUMAN,tr|A0A2R8Y8C1|A0A2R8Y8C1_HUMAN,tr|A0A0C4DGG9|A0A0C4DGG9_HUMAN,tr|A0A2R8YFD8|A0A2R8YFD8_HUMAN,tr|A0A2R8YDW2|A0A2R8YDW2_HUMAN,tr|A0A2R8Y5Z7|A0A2R8Y5Z7_HUMAN,tr|F5GWX5|F5GWX5_HUMAN,tr|A0A2R8YER1|A0A2R8YER1_HUMAN,tr|A0A2R8Y521|A0A2R8Y521_HUMAN,tr|A0A2R8YDJ9|A0A2R8YDJ9_HUMAN,tr|A0A2R8Y212|A0A2R8Y212_HUMAN,tr|A0A2R8YE38|A0A2R8YE38_HUMAN" 20 2006.9473 1.29 68130 16756 3 2006.946351 669.9897 Chromodomain-helicase-DNA-binding protein 4 OS=Homo sapiens OX=9606 GN=CHD4 PE=1 SV=2 4.08 2904 - 596938 - - - -0.4744 - 1.851 0.258 - 95.6 1 2 1 -0.001 16 0 0 0 4.36E+06 3.37E+06 - - - 2.9961 1 221125_WJC_METTL3_EV_vs_WT_F05.16757.16757.3 8.58E-10 22/76 R.VPFSPGPAPPPHMGELDQER[166.11].L "sp|Q6Y7W6|GGYF2_HUMAN,tr|A0A7I2V3H7|A0A7I2V3H7_HUMAN,tr|I1E4Y6|I1E4Y6_HUMAN,tr|A0A7I2V516|A0A7I2V516_HUMAN,tr|A0A7I2V3H0|A0A7I2V3H0_HUMAN,tr|C9JHW1|C9JHW1_HUMAN,tr|A0A7I2V361|A0A7I2V361_HUMAN,tr|E7ESB6|E7ESB6_HUMAN" 8 2167.0396 4.19 68131 16757 3 2167.042733 723.3538 GRB10-interacting GYF protein 2 OS=Homo sapiens OX=9606 GN=GIGYF2 PE=1 SV=1 4.65 2904.1 - 475381 - - - 1.4485 - 4.509 0.694 - 534.2 1 2 0 0.0031 20 0 0 0 7.06E+07 1.69E+07 - - - 9.9303 1 221125_WJC_METTL3_EV_vs_WT_F05.16758.16758.3 3.11E-08 21/76 K.LGHVVMGNNAVSPYQQVIEK.T "sp|P60228|EIF3E_HUMAN,tr|H0YBP5|H0YBP5_HUMAN,tr|A0A7I2V5Z6|A0A7I2V5Z6_HUMAN,tr|A0A7I2V2H9|A0A7I2V2H9_HUMAN,tr|B3KW56|B3KW56_HUMAN,tr|H0YAW4|H0YAW4_HUMAN,tr|A0A7I2V4B4|A0A7I2V4B4_HUMAN,tr|E5RGA2|E5RGA2_HUMAN,tr|A0A7I2V3I0|A0A7I2V3I0_HUMAN,tr|A0A7I2V3S3|A0A7I2V3S3_HUMAN,tr|A0A7I2V4G3|A0A7I2V4G3_HUMAN,tr|E5RHS5|E5RHS5_HUMAN,tr|A0A7I2V2W0|A0A7I2V2W0_HUMAN,tr|A0A7I2V5P9|A0A7I2V5P9_HUMAN" 14 2182.1205 2.94 68132 16758 3 2182.12447 728.3808 Eukaryotic translation initiation factor 3 subunit E OS=Homo sapiens OX=9606 GN=EIF3E PE=1 SV=1 6.75 2904.2 - 447350 - - - 1.8317 - 4.237 0.6 - 534.8 1 2 0 0.004 20 0 0 0 1.08E+07 3.67E+06 - - - 8.7311 0.9715 221125_WJC_METTL3_EV_vs_WT_F05.16769.16769.4 0.000835 14/90 S.WLDANTLAEK[136.11]DEFEHK[136.11].R "sp|P0DMV8|HS71A_HUMAN,sp|P0DMV9|HS71B_HUMAN,tr|V9GZ37|V9GZ37_HUMAN,tr|A0A0G2JIW1|A0A0G2JIW1_HUMAN" 4 1960.9502 0.43 68141 16769 4 1960.953341 491.2448 Heat shock 70 kDa protein 1A OS=Homo sapiens OX=9606 GN=HSPA1A PE=1 SV=1 4.5 2905.6 - 1.68E+06 - - - 1.6237 - 2.974 0.465 - 166.8 1 1 1 0.0032 16 0 0 0 7.30E+06 1.71E+07 - - - 3.6564 1 221125_WJC_METTL3_EV_vs_WT_F05.16770.16770.3 1.33E-08 15/48 R.K[136.11]EFSPFGTITSAK[136.11].V "sp|P11940|PABP1_HUMAN,tr|A0A7I2YQE4|A0A7I2YQE4_HUMAN,tr|A0A7I2V649|A0A7I2V649_HUMAN,tr|H0YB86|H0YB86_HUMAN,tr|H0YAR2|H0YAR2_HUMAN,tr|E7ERJ7|E7ERJ7_HUMAN,tr|A0A7I2YQ88|A0A7I2YQ88_HUMAN,tr|A0A087WTT1|A0A087WTT1_HUMAN,tr|H0YAP2|H0YAP2_HUMAN,tr|A0A7I2V4N4|A0A7I2V4N4_HUMAN,tr|E7EQV3|E7EQV3_HUMAN" 11 1427.7631 1.43 68142 16770 3 1427.764581 476.9283 Polyadenylate-binding protein 1 OS=Homo sapiens OX=9606 GN=PABPC1 PE=1 SV=2 8.59 2905.6 - 1.25E+06 - - - 1.0156 - 2.616 0.598 - 350.4 1 2 0 0.0014 13 0 0 0 2.96E+08 2.06E+08 - - - 7.814 1 221125_WJC_METTL3_EV_vs_WT_F05.16771.16771.2 2.32E-12 19/38 F.GGGSGFSGGGFGGGGFGGGR.F sp|P35908|K22E_HUMAN 1 1587.6815 999 68143 16771 2 1587.681787 794.848 "Keratin, type II cytoskeletal 2 epidermal OS=Homo sapiens OX=9606 GN=KRT2 PE=1 SV=2" 9.75 2905.8 - 1.15E+06 - - - 0.2016 - 3.807 0.642 - 817.2 1 1 0 0.0003 20 0 0 0 1.31E+07 0.00E+00 - - - 7.0694 0.9979 221125_WJC_METTL3_EV_vs_WT_F05.16776.16776.2 6.12E-07 18/36 K.ATAAPAGAPPQPQDLEFTK.L "sp|P22695|QCR2_HUMAN,tr|H3BUE4|H3BUE4_HUMAN,tr|H3BUI9|H3BUI9_HUMAN,tr|H3BRG4|H3BRG4_HUMAN,tr|H3BSJ9|H3BSJ9_HUMAN" 5 1908.9581 2.47 68148 16776 2 1908.947851 955.4863 "Cytochrome b-c1 complex subunit 2, mitochondrial OS=Homo sapiens OX=9606 GN=UQCRC2 PE=1 SV=3" 4.37 2906.4 - 519744 - - - -5.3909 - 2.564 0.59 - 541.3 1 2 0 -0.0103 19 0 0 0 1.46E+07 5.92E+06 - - - 5.7104 1 221125_WJC_METTL3_EV_vs_WT_F05.16778.16778.2 3.77E-11 17/28 K.NQVAMNPTNTVFDAK.R "sp|P11142|HSP7C_HUMAN,tr|E9PQQ4|E9PQQ4_HUMAN,tr|E9PNE6|E9PNE6_HUMAN,tr|E9PKE3|E9PKE3_HUMAN,tr|E9PLF4|E9PLF4_HUMAN,tr|E9PK54|E9PK54_HUMAN,tr|E9PN25|E9PN25_HUMAN,tr|E9PPY6|E9PPY6_HUMAN,tr|E9PQK7|E9PQK7_HUMAN" 9 1648.7879 0.15 68150 16778 2 1648.789084 825.4012 Heat shock cognate 71 kDa protein OS=Homo sapiens OX=9606 GN=HSPA8 PE=1 SV=1 5.84 2906.6 - 446035 - - - 0.7145 - 3.108 0.692 - 781.8 1 2 0 0.0012 15 0 0 0 7.42E+07 4.91E+08 - - - 6.9397 0.9999 221125_WJC_METTL3_EV_vs_WT_F05.16782.16782.3 2.30E-09 18/72 R.TQTAIASEDMPNTLTEAEK.L "sp|Q01082|SPTB2_HUMAN,tr|A0A087WUZ3|A0A087WUZ3_HUMAN" 2 2048.9572 1.09 68154 16782 3 2048.965046 683.993 "Spectrin beta chain, non-erythrocytic 1 OS=Homo sapiens OX=9606 GN=SPTBN1 PE=1 SV=2" 4 2907.1 - 244042 - - - 3.8215 - 3.255 0.559 - 439 1 2 0 0.0078 19 0 0 0 5.19E+06 4.78E+06 - - - 7.6696 0.9999 221125_WJC_METTL3_EV_vs_WT_F05.16783.16783.3 1.80E-05 11/100 R.VVNAAIATASSASGEPEEPVVPSTTR.G "sp|O15020|SPTN2_HUMAN,tr|A4QPE4|A4QPE4_HUMAN" 2 2539.2766 9.11 68155 16783 3 2539.273455 847.4328 "Spectrin beta chain, non-erythrocytic 2 OS=Homo sapiens OX=9606 GN=SPTBN2 PE=1 SV=3" 4.25 2907.2 - 203770 - - - -1.2291 - 2.042 0.478 - 78.4 1 2 0 -0.0031 26 0 0 0 1.11E+06 1.21E+05 - - - 5.5109 1 221125_WJC_METTL3_EV_vs_WT_F05.16786.16786.4 6.88E-11 23/108 R.LLEAQIATGGVIDPVHSHR.V "sp|P58107|EPIPL_HUMAN,sp|P58107|EPIPL_HUMAN,sp|P58107|EPIPL_HUMAN,sp|P58107|EPIPL_HUMAN,sp|P58107|EPIPL_HUMAN,sp|P58107|EPIPL_HUMAN,sp|Q15149|PLEC_HUMAN,tr|A0A075B730|A0A075B730_HUMAN,tr|A0A075B730|A0A075B730_HUMAN,tr|A0A075B730|A0A075B730_HUMAN,tr|A0A075B730|A0A075B730_HUMAN,tr|A0A075B730|A0A075B730_HUMAN,tr|A0A075B730|A0A075B730_HUMAN,tr|H0YDN1|H0YDN1_HUMAN" 14 2012.0803 1.74 68156 16786 4 2012.081164 504.0274 Epiplakin OS=Homo sapiens OX=9606 GN=EPPK1 PE=1 SV=3 5.99 2907.6 - 5.70E+06 - - - 0.418 - 3.747 0.629 - 498.5 1 2 0 0.0008 19 0 0 0 1.14E+08 6.54E+07 - - - 5.1474 0.9996 221125_WJC_METTL3_EV_vs_WT_F05.16787.16787.4 0.00206 19/108 R.LLEAQIATGGVIDPVHSHR[166.11].V "sp|P58107|EPIPL_HUMAN,sp|P58107|EPIPL_HUMAN,sp|P58107|EPIPL_HUMAN,sp|P58107|EPIPL_HUMAN,sp|P58107|EPIPL_HUMAN,sp|P58107|EPIPL_HUMAN,sp|Q15149|PLEC_HUMAN,tr|A0A075B730|A0A075B730_HUMAN,tr|A0A075B730|A0A075B730_HUMAN,tr|A0A075B730|A0A075B730_HUMAN,tr|A0A075B730|A0A075B730_HUMAN,tr|A0A075B730|A0A075B730_HUMAN,tr|A0A075B730|A0A075B730_HUMAN,tr|H0YDN1|H0YDN1_HUMAN" 14 2022.0886 1.74 68157 16787 4 2022.086596 506.5294 Epiplakin OS=Homo sapiens OX=9606 GN=EPPK1 PE=1 SV=3 5.99 2907.7 - 4.20E+06 - - - -0.9876 - 2.283 0.347 - 134.1 1 2 0 -0.002 19 0 0 0 1.14E+08 6.58E+07 - - - 2.525 1 221125_WJC_METTL3_EV_vs_WT_F05.16788.16788.3 1.28E-06 13/64 K.VSYIPDEQIAQGPENGR[166.11].R sp|Q9NZI8|IF2B1_HUMAN 1 1881.9096 3.97 68158 16788 3 1881.909671 628.3105 Insulin-like growth factor 2 mRNA-binding protein 1 OS=Homo sapiens OX=9606 GN=IGF2BP1 PE=1 SV=2 4.14 2907.7 - 2.19E+06 - - - 0.0239 - 2.001 0.532 - 184.9 1 2 0 0 17 0 0 0 1.64E+08 4.13E+07 - - - 6.2236 1 221125_WJC_METTL3_EV_vs_WT_F05.16789.16789.2 2.82E-07 24-Nov R.TTPSYVAFTDTER.L "sp|P48741|HSP77_HUMAN,sp|P54652|HSP72_HUMAN,sp|P0DMV8|HS71A_HUMAN,sp|P34931|HS71L_HUMAN,sp|P11142|HSP7C_HUMAN,sp|P0DMV9|HS71B_HUMAN,sp|P17066|HSP76_HUMAN,tr|E9PQQ4|E9PQQ4_HUMAN,tr|E9PNE6|E9PNE6_HUMAN,tr|E9PKE3|E9PKE3_HUMAN,tr|E9PLF4|E9PLF4_HUMAN,tr|Q53FA3|Q53FA3_HUMAN,tr|E9PI65|E9PI65_HUMAN,tr|E9PK54|E9PK54_HUMAN,tr|E9PN25|E9PN25_HUMAN,tr|E9PPY6|E9PPY6_HUMAN,tr|E9PQK7|E9PQK7_HUMAN,tr|A0A0G2JIW1|A0A0G2JIW1_HUMAN" 18 1486.694 0.14 68159 16789 2 1486.69441 744.3543 Putative heat shock 70 kDa protein 7 OS=Homo sapiens OX=9606 GN=HSPA7 PE=5 SV=2 4.37 2907.8 - 1.94E+06 - - - 0.2832 - 2.443 0.637 - 444.6 1 2 0 0.0004 13 0 0 0 1.83E+07 1.27E+08 - - - 6.0382 0.997 221125_WJC_METTL3_EV_vs_WT_F05.16790.16790.3 0.000939 Dec-56 R.ELQELVQYPVEHPDK.F "sp|P55072|TERA_HUMAN,tr|A0A7P0Z4C6|A0A7P0Z4C6_HUMAN,tr|A0A7P0T8Q5|A0A7P0T8Q5_HUMAN,tr|C9JUP7|C9JUP7_HUMAN,tr|A0A7P0TAW3|A0A7P0TAW3_HUMAN,tr|A0A7I2V540|A0A7I2V540_HUMAN,tr|A0A7P0T8A3|A0A7P0T8A3_HUMAN,tr|A0A7P0TAQ1|A0A7P0TAQ1_HUMAN" 8 1822.9101 1.12 68160 16790 3 1822.920343 608.644 Transitional endoplasmic reticulum ATPase OS=Homo sapiens OX=9606 GN=VCP PE=1 SV=4 4.4 2907.9 - 1.67E+06 - - - 5.6031 - 2.197 0.398 - 185.7 1 2 0 0.0102 15 0 0 0 3.07E+07 2.73E+07 - - - 5.0283 1 221125_WJC_METTL3_EV_vs_WT_F05.16792.16792.3 0.000152 16/56 K.NQVAMNPTNTVFDAK[136.11].R "sp|P11142|HSP7C_HUMAN,tr|E9PQQ4|E9PQQ4_HUMAN,tr|E9PNE6|E9PNE6_HUMAN,tr|E9PKE3|E9PKE3_HUMAN,tr|E9PLF4|E9PLF4_HUMAN,tr|E9PK54|E9PK54_HUMAN,tr|E9PN25|E9PN25_HUMAN,tr|E9PPY6|E9PPY6_HUMAN,tr|E9PQK7|E9PQK7_HUMAN" 9 1656.8021 0.28 68162 16792 3 1656.799358 553.2746 Heat shock cognate 71 kDa protein OS=Homo sapiens OX=9606 GN=HSPA8 PE=1 SV=1 5.84 2908.1 - 857752 - - - -1.6586 - 3.071 0.45 - 402.4 1 2 0 -0.0027 15 0 0 0 7.93E+06 2.79E+07 - - - 6.484 1 221125_WJC_METTL3_EV_vs_WT_F05.16793.16793.2 0.000202 15/24 R.K[136.11]EFSPFGTITSAK[136.11].V "sp|P11940|PABP1_HUMAN,tr|A0A7I2YQE4|A0A7I2YQE4_HUMAN,tr|A0A7I2V649|A0A7I2V649_HUMAN,tr|H0YB86|H0YB86_HUMAN,tr|H0YAR2|H0YAR2_HUMAN,tr|E7ERJ7|E7ERJ7_HUMAN,tr|A0A7I2YQ88|A0A7I2YQ88_HUMAN,tr|A0A087WTT1|A0A087WTT1_HUMAN,tr|H0YAP2|H0YAP2_HUMAN,tr|A0A7I2V4N4|A0A7I2V4N4_HUMAN,tr|E7EQV3|E7EQV3_HUMAN" 11 1427.7631 1.48 68163 16793 2 1427.762076 714.8888 Polyadenylate-binding protein 1 OS=Homo sapiens OX=9606 GN=PABPC1 PE=1 SV=2 8.59 2908.2 - 814297 - - - -0.7389 - 3.224 0.535 - 647 1 2 0 -0.0011 13 0 0 0 6.73E+07 4.54E+07 - - - 5.9966 1 221125_WJC_METTL3_EV_vs_WT_F05.16795.16795.2 3.03E-13 16/36 R.TQTAIASEDMPNTLTEAEK.L "sp|Q01082|SPTB2_HUMAN,tr|A0A087WUZ3|A0A087WUZ3_HUMAN" 2 2048.9572 2.17 68165 16795 2 2048.955684 1025.4859 "Spectrin beta chain, non-erythrocytic 1 OS=Homo sapiens OX=9606 GN=SPTBN1 PE=1 SV=2" 4 2908.5 - 506351 - - - -0.7477 - 3.281 0.692 - 606.9 1 2 0 -0.0015 19 0 0 0 7.16E+06 3.30E+06 - - - 7.0727 0.982 221125_WJC_METTL3_EV_vs_WT_F05.16798.16798.3 0.17 Sep-48 R.SASLISQAEHSLK[136.11].E "sp|O15344|TRI18_HUMAN,tr|C9J453|C9J453_HUMAN,tr|A0A087X255|A0A087X255_HUMAN,tr|A0A6Q8PGE7|A0A6Q8PGE7_HUMAN,tr|A0A6Q8PGA5|A0A6Q8PGA5_HUMAN,tr|A0A6Q8PF94|A0A6Q8PF94_HUMAN" 6 1377.7343 3.53 68168 16798 3 1377.734777 460.2521 E3 ubiquitin-protein ligase Midline-1 OS=Homo sapiens OX=9606 GN=MID1 PE=1 SV=1 6.47 2908.9 - 392131 - - - 0.3143 - 1.486 0.165 - 79.7 1 2 0 0.0004 13 0 0 0 8.72E+06 2.47E+06 - - - 1.4534 1 221125_WJC_METTL3_EV_vs_WT_F05.16799.16799.3 2.60E-08 14/56 K.HDAATC[160.03]FVDAGNAFK.K "sp|P54920|SNAA_HUMAN,tr|M0R2M1|M0R2M1_HUMAN,tr|M0R0I4|M0R0I4_HUMAN,tr|M0R058|M0R058_HUMAN" 4 1622.7147 1.08 68169 16799 3 1622.716395 541.9122 Alpha-soluble NSF attachment protein OS=Homo sapiens OX=9606 GN=NAPA PE=1 SV=3 5.21 2909 - 292567 - - - 1.0193 - 2.667 0.591 - 139.9 1 2 0 0.0017 15 0 0 0 1.62E+06 1.50E+06 - - - 7.6883 0.9999 221125_WJC_METTL3_EV_vs_WT_F05.16806.16806.2 0.00282 13/22 K.DQIVDLTVGNNK.T sp|P35527|K1C9_HUMAN 1 1314.6779 999 68174 16806 2 1314.6772 658.3462 "Keratin, type I cytoskeletal 9 OS=Homo sapiens OX=9606 GN=KRT9 PE=1 SV=3" 4.21 2909.8 - 2.38E+06 - - - -0.5667 - 2.48 0.424 - 448.8 1 2 0 -0.0007 12 0 0 0 5.64E+07 0.00E+00 - - - 4.5622 1 221125_WJC_METTL3_EV_vs_WT_F05.16807.16807.3 5.05E-09 19/76 K.VGDGDLSAEEIPENEVSLR[166.11]R[166.11].A sp|Q14684|RRP1B_HUMAN 1 2204.0824 0.89 68175 16807 3 2204.081191 735.7014 Ribosomal RNA processing protein 1 homolog B OS=Homo sapiens OX=9606 GN=RRP1B PE=1 SV=3 4.08 2910 - 968714 - - - -0.5463 - 3.307 0.542 - 385.3 1 2 0 -0.0012 20 0 0 0 5.88E+06 6.59E+06 - - - 7.4841 1 221125_WJC_METTL3_EV_vs_WT_F05.16810.16810.4 8.25E-07 22/90 R.ISHLVLPVQPENALKR.G "sp|Q5JTV8|TOIP1_HUMAN,tr|J3KN66|J3KN66_HUMAN,tr|A0A0A0MSK5|A0A0A0MSK5_HUMAN" 3 1813.0574 1.42 68178 16810 4 1813.054923 454.2716 Torsin-1A-interacting protein 1 OS=Homo sapiens OX=9606 GN=TOR1AIP1 PE=1 SV=2 8.75 2910.4 - 723121 - - - -1.3679 - 2.846 0.495 - 317.4 1 2 0 -0.0025 16 0 0 0 6.98E+06 4.91E+06 - - - 3.9022 0.9743 221125_WJC_METTL3_EV_vs_WT_F05.16812.16812.3 0.035 Nov-52 K.NR[166.11]ETIASVRSLEGR[166.11].F tr|E9PHV4|E9PHV4_HUMAN 1 1606.8654 - 68180 16812 3 1606.864498 536.6291 DNA-directed RNA polymerase II subunit RPB4 OS=Homo sapiens OX=9606 GN=POLR2D PE=1 SV=1 9.51 2910.6 - 457636 - - - -0.5651 - 1.949 0.165 - 91.4 1 2 2 -0.0009 14 0 0 0 - - - - - 2.1528 0.9985 221125_WJC_METTL3_EV_vs_WT_F05.16813.16813.2 0.000241 14/36 K.ATAAPAGAPPQPQDLEFTK[136.11].L "sp|P22695|QCR2_HUMAN,tr|H3BUE4|H3BUE4_HUMAN,tr|H3BUI9|H3BUI9_HUMAN,tr|H3BRG4|H3BRG4_HUMAN,tr|H3BSJ9|H3BSJ9_HUMAN" 5 1916.9723 1.59 68181 16813 2 1916.964571 959.4934 "Cytochrome b-c1 complex subunit 2, mitochondrial OS=Homo sapiens OX=9606 GN=UQCRC2 PE=1 SV=3" 4.37 2910.8 - 371569 - - - -4.0538 - 1.791 0.542 - 330 1 2 0 -0.0078 19 0 0 0 5.83E+06 3.67E+06 - - - 4.4745 1 221125_WJC_METTL3_EV_vs_WT_F05.16819.16819.2 6.27E-07 19/24 R.KEFSPFGTITSAK.V "sp|P11940|PABP1_HUMAN,tr|A0A7I2YQE4|A0A7I2YQE4_HUMAN,tr|A0A7I2V649|A0A7I2V649_HUMAN,tr|H0YB86|H0YB86_HUMAN,tr|H0YAR2|H0YAR2_HUMAN,tr|E7ERJ7|E7ERJ7_HUMAN,tr|A0A7I2YQ88|A0A7I2YQ88_HUMAN,tr|A0A087WTT1|A0A087WTT1_HUMAN,tr|H0YAP2|H0YAP2_HUMAN,tr|A0A7I2V4N4|A0A7I2V4N4_HUMAN,tr|E7EQV3|E7EQV3_HUMAN" 11 1411.7347 1.48 68185 16819 2 1411.735418 706.8746 Polyadenylate-binding protein 1 OS=Homo sapiens OX=9606 GN=PABPC1 PE=1 SV=2 8.59 2911.3 - 3.26E+06 - - - 0.4866 - 3.026 0.558 - 432.7 1 2 0 0.0007 13 0 0 0 6.74E+07 4.54E+07 - - - 6.0039 0.9998 221125_WJC_METTL3_EV_vs_WT_F05.16821.16821.2 2.17E-05 13/26 R.ETLLNSATTSLNSK[136.11].V sp|P50991|TCPD_HUMAN 1 1485.7766 0.29 68187 16821 2 1485.774089 743.8956 T-complex protein 1 subunit delta OS=Homo sapiens OX=9606 GN=CCT4 PE=1 SV=4 6.1 2911.4 - 1.83E+06 - - - -1.6914 - 2.55 0.524 - 577.8 1 2 0 -0.0025 14 0 0 0 8.23E+06 2.88E+07 - - - 5.2596 0.9998 221125_WJC_METTL3_EV_vs_WT_F05.16823.16823.4 1.86E-05 19/90 R.LLIYKVSNRFSGVPDR.F sp|A0A075B6R9|KVD24_HUMAN 1 1863.0367 999 68189 16823 4 1863.035388 466.7664 Probable non-functional immunoglobulin kappa variable 2D-24 OS=Homo sapiens OX=9606 GN=IGKV2D-24 PE=1 SV=1 9.99 2911.7 - 1.10E+06 - - - -0.6865 - 2.629 0.476 - 292.3 1 2 2 -0.0013 16 0 0 0 1.01E+08 0.00E+00 - - - 3.7092 0.9836 221125_WJC_METTL3_EV_vs_WT_F05.16829.16829.3 0.000195 16/72 Q.SSELVSWADGGQHSSIHPA.- "sp|O00746|NDKM_HUMAN,tr|Q4TT34|Q4TT34_HUMAN,tr|A0A087WVT9|A0A087WVT9_HUMAN" 3 1963.9024 - 68193 16829 3 1963.909726 655.6414 "Nucleoside diphosphate kinase, mitochondrial OS=Homo sapiens OX=9606 GN=NME4 PE=1 SV=1" 5.14 2912.5 - 1.73E+06 - - - 3.7212 - 3.504 0.463 - 229.8 1 1 0 0.0073 19 0 0 0 - - - - - 6.7806 0.9998 221125_WJC_METTL3_EV_vs_WT_F05.16831.16831.3 7.20E-06 13/60 R.LLIYKVSNRFSGVPDR.F sp|A0A075B6R9|KVD24_HUMAN 1 1863.0367 288.61 68195 16831 3 1863.035971 622.0195 Probable non-functional immunoglobulin kappa variable 2D-24 OS=Homo sapiens OX=9606 GN=IGKV2D-24 PE=1 SV=1 9.99 2912.7 - 1.41E+06 - - - -0.3736 - 2.327 0.469 - 213.6 1 2 2 -0.0007 16 0 0 0 8.67E+07 3.00E+05 - - - 5.9358 0.9998 221125_WJC_METTL3_EV_vs_WT_F05.16832.16832.4 8.77E-05 13/90 K.LEQMPSKEDAIEHFMK.L "sp|P09874|PARP1_HUMAN,tr|A0A7I2V3E1|A0A7I2V3E1_HUMAN" 2 1931.9121 0.82 68196 16832 4 1931.912143 483.9853 Poly [ADP-ribose] polymerase 1 OS=Homo sapiens OX=9606 GN=PARP1 PE=1 SV=4 4.83 2912.8 - 1.13E+06 - - - 0.0119 - 3.28 0.467 - 133.5 1 2 1 0 16 0 0 0 9.56E+06 1.17E+07 - - - 3.7092 0.9998 221125_WJC_METTL3_EV_vs_WT_F05.16835.16835.3 2.08E-05 Dec-40 K.K[136.11]LDIGLELVHK[136.11].G "sp|Q9Y2W6|TDRKH_HUMAN,tr|F6TB26|F6TB26_HUMAN,tr|Q5SZR4|Q5SZR4_HUMAN" 3 1279.7835 1.14 68199 16835 3 1279.77987 427.6018 Tudor and KH domain-containing protein OS=Homo sapiens OX=9606 GN=TDRKH PE=1 SV=2 6.75 2913.2 - 631861 - - - -2.8153 - 2.464 0.415 - 227 1 2 0 -0.0036 11 0 0 0 7.51E+06 6.61E+06 - - - 5.7277 0.9991 221125_WJC_METTL3_EV_vs_WT_F05.16837.16837.3 0.000696 Oct-72 K.IPDPEAVK[136.11]PDDWDEDAPAK[136.11].L "sp|P27824|CALX_HUMAN,tr|A0A7P0T937|A0A7P0T937_HUMAN,tr|A0A7P0T840|A0A7P0T840_HUMAN,tr|A0A7P0TB65|A0A7P0TB65_HUMAN,tr|A0A7P0TAE9|A0A7P0TAE9_HUMAN,tr|D6RGY2|D6RGY2_HUMAN,tr|A0A7P0T8G1|A0A7P0T8G1_HUMAN,tr|A0A7P0Z4D6|A0A7P0Z4D6_HUMAN,tr|A0A7P0Z484|A0A7P0Z484_HUMAN,tr|A0A7P0TAR9|A0A7P0TAR9_HUMAN,tr|A0A7P0T9L0|A0A7P0T9L0_HUMAN" 11 2123.003 1.72 68201 16837 3 2122.998459 708.6749 Calnexin OS=Homo sapiens OX=9606 GN=CANX PE=1 SV=2 3.85 2913.5 - 496516 - - - -2.1295 - 1.941 0.334 - 49.3 1 2 0 -0.0045 19 0 0 0 3.18E+07 1.85E+07 - - - 3.8919 0.9704 221125_WJC_METTL3_EV_vs_WT_F05.16843.16843.3 0.0182 Dec-52 K.SLEELR[166.11]LEDYQANR[166.11].K "sp|P52948|NUP98_HUMAN,tr|A0A3B3ITD8|A0A3B3ITD8_HUMAN" 2 1754.8702 0.99 68205 16843 3 1754.865081 585.964 Nuclear pore complex protein Nup98-Nup96 OS=Homo sapiens OX=9606 GN=NUP98 PE=1 SV=4 4.41 2914.1 - 1.05E+06 - - - -2.9267 - 1.756 0.255 - 140.9 1 2 1 -0.0051 14 0 0 0 2.38E+07 2.40E+07 - - - 2.8779 0.9999 221125_WJC_METTL3_EV_vs_WT_F05.16852.16852.3 4.61E-06 14/80 K.IWSTVPTDEEDEMEESTNR[166.11]PR[166.11].K sp|Q9GZL7|WDR12_HUMAN 1 2540.124 1.79 68212 16852 3 2540.115123 847.7153 Ribosome biogenesis protein WDR12 OS=Homo sapiens OX=9606 GN=WDR12 PE=1 SV=2 4 2915.1 - 1.04E+06 - - - -3.4955 - 2.662 0.553 - 131.5 1 2 0 -0.0089 21 0 0 0 1.62E+07 9.07E+06 - - - 7.0502 0.9968 221125_WJC_METTL3_EV_vs_WT_F05.16853.16853.3 0.00289 Dec-64 R.IIKDFMIQGGDPTGTGR.G sp|Q9Y3C6|PPIL1_HUMAN 1 1804.9142 1.58 68213 16853 3 1804.917706 602.6453 Peptidyl-prolyl cis-trans isomerase-like 1 OS=Homo sapiens OX=9606 GN=PPIL1 PE=1 SV=1 5.96 2915.3 - 993782 - - - 1.9596 - 2.437 0.294 - 114.3 1 2 1 0.0035 17 0 0 0 1.47E+07 9.31E+06 - - - 4.0672 0.9868 221125_WJC_METTL3_EV_vs_WT_F05.16866.16866.3 6.86E-05 15/52 N.GNPITIFQERDPSK.L sp|P04406|G3P_HUMAN 1 1600.8209 0.98 68221 16866 3 1600.819256 534.6142 Glyceraldehyde-3-phosphate dehydrogenase OS=Homo sapiens OX=9606 GN=GAPDH PE=1 SV=3 6.07 2916.8 - 215246 - - - -1.0395 - 2.592 0.499 - 324.1 1 1 1 -0.0017 14 0 0 0 2.10E+07 2.14E+07 - - - 6.634 0.9999 221125_WJC_METTL3_EV_vs_WT_F05.16871.16871.3 5.33E-07 15/60 R.K[136.11]NEALAPPLLDAEPAR[166.11].G sp|Q10469|MGAT2_HUMAN 1 1721.9431 1.62 68224 16871 3 1721.938242 574.9883 "Alpha-1,6-mannosyl-glycoprotein 2-beta-N-acetylglucosaminyltransferase OS=Homo sapiens OX=9606 GN=MGAT2 PE=1 SV=1" 4.68 2917.4 - 2.73E+06 - - - -2.8236 - 2.699 0.539 - 266.4 1 2 0 -0.0049 16 0 0 0 1.07E+08 6.60E+07 - - - 7.0956 0.9999 221125_WJC_METTL3_EV_vs_WT_F05.16872.16872.3 1.61E-07 19/72 R.NALVSHLDGTTPVC[160.03]EDIGR.S sp|P31930|QCR1_HUMAN 1 2052.9899 1.18 68225 16872 3 2052.982634 685.3372 "Cytochrome b-c1 complex subunit 1, mitochondrial OS=Homo sapiens OX=9606 GN=UQCRC1 PE=1 SV=3" 4.54 2917.6 - 1.07E+06 - - - -3.5163 - 3.178 0.615 - 463.4 1 2 0 -0.0072 19 0 0 0 3.57E+07 3.03E+07 - - - 8.2353 1 221125_WJC_METTL3_EV_vs_WT_F05.16874.16874.3 1.09E-06 Dec-56 K.GYGFVHFETQEAAER.A "sp|P11940|PABP1_HUMAN,tr|A0A7I2YQE4|A0A7I2YQE4_HUMAN,tr|A0A7I2V649|A0A7I2V649_HUMAN,tr|H0YAR2|H0YAR2_HUMAN,tr|E7ERJ7|E7ERJ7_HUMAN,tr|A0A7I2YQ88|A0A7I2YQ88_HUMAN,tr|H0YBN4|H0YBN4_HUMAN,tr|E5RGH3|E5RGH3_HUMAN,tr|A0A087WTT1|A0A087WTT1_HUMAN,tr|A0A7I2YQ90|A0A7I2YQ90_HUMAN,tr|A0A7I2V4N4|A0A7I2V4N4_HUMAN,tr|E7EQV3|E7EQV3_HUMAN" 12 1739.7903 0.71 68227 16874 3 1739.787228 580.9374 Polyadenylate-binding protein 1 OS=Homo sapiens OX=9606 GN=PABPC1 PE=1 SV=2 4.75 2917.6 - 3.62E+06 - - - -1.7939 - 2.502 0.558 - 151.1 1 2 0 -0.0031 15 0 0 0 5.21E+07 7.36E+07 - - - 7.1533 0.9999 221125_WJC_METTL3_EV_vs_WT_F05.16877.16877.3 3.12E-09 20/72 K.AAGFK[136.11]DPLLASGTDGVGTK[136.11].L sp|P22102|PUR2_HUMAN 1 1819.9651 4.41 68230 16877 3 1819.96845 607.6623 Trifunctional purine biosynthetic protein adenosine-3 OS=Homo sapiens OX=9606 GN=GART PE=1 SV=1 6 2918 - 836952 - - - 1.8522 - 3.618 0.546 - 571.4 1 2 1 0.0034 19 0 0 0 1.44E+08 3.27E+07 - - - 7.7857 1 221125_WJC_METTL3_EV_vs_WT_F05.16878.16878.2 3.61E-09 26-Dec R.ETVSEESNVLC[160.03]LSK[136.11].S sp|P13639|EF2_HUMAN 1 1601.7698 0.001 68231 16878 2 1601.765221 801.8922 Elongation factor 2 OS=Homo sapiens OX=9606 GN=EEF2 PE=1 SV=4 4.25 2918.2 - 739266 - - - -2.8606 - 2.408 0.617 - 529.9 1 2 0 -0.0046 14 0 0 0 0.00E+00 8.56E+06 - - - 5.802 0.9999 221125_WJC_METTL3_EV_vs_WT_F05.16879.16879.3 0.0027 Dec-60 K.QFNYTHIC[160.03]AGASAFGK[136.11].N "sp|P13804|ETFA_HUMAN,tr|H0YL12|H0YL12_HUMAN,tr|H0YKF0|H0YKF0_HUMAN,tr|H0YLU7|H0YLU7_HUMAN,tr|H0YNX6|H0YNX6_HUMAN" 5 1778.829 1.18 68232 16879 3 1778.82674 593.9503 "Electron transfer flavoprotein subunit alpha, mitochondrial OS=Homo sapiens OX=9606 GN=ETFA PE=1 SV=1" 8.21 2918.3 - 735164 - - - -1.2643 - 2.401 0.456 - 171.9 1 2 0 -0.0022 16 0 0 0 1.47E+07 1.25E+07 - - - 5.8707 1 221125_WJC_METTL3_EV_vs_WT_F05.16885.16885.3 2.02E-07 13/56 K.GYGFVHFETQEAAER[166.11].A "sp|P11940|PABP1_HUMAN,tr|A0A7I2YQE4|A0A7I2YQE4_HUMAN,tr|A0A7I2V649|A0A7I2V649_HUMAN,tr|H0YAR2|H0YAR2_HUMAN,tr|E7ERJ7|E7ERJ7_HUMAN,tr|A0A7I2YQ88|A0A7I2YQ88_HUMAN,tr|H0YBN4|H0YBN4_HUMAN,tr|E5RGH3|E5RGH3_HUMAN,tr|A0A087WTT1|A0A087WTT1_HUMAN,tr|A0A7I2YQ90|A0A7I2YQ90_HUMAN,tr|A0A7I2V4N4|A0A7I2V4N4_HUMAN,tr|E7EQV3|E7EQV3_HUMAN" 12 1749.7986 0.7 68236 16885 3 1749.796665 584.2735 Polyadenylate-binding protein 1 OS=Homo sapiens OX=9606 GN=PABPC1 PE=1 SV=2 4.75 2918.9 - 4.11E+06 - - - -1.1167 - 2.649 0.552 - 144.8 1 2 0 -0.002 15 0 0 0 5.11E+07 7.32E+07 - - - 7.2357 1 221125_WJC_METTL3_EV_vs_WT_F05.16886.16886.3 1.17E-05 26/72 R.NALVSHLDGTTPVC[160.03]EDIGR[166.11].S sp|P31930|QCR1_HUMAN 1 2062.9981 1.17 68237 16886 3 2062.995266 688.6733 "Cytochrome b-c1 complex subunit 1, mitochondrial OS=Homo sapiens OX=9606 GN=UQCRC1 PE=1 SV=3" 4.54 2919.1 - 1.96E+06 - - - -1.3849 - 4.029 0.632 - 841.6 1 2 0 -0.0029 19 0 0 0 3.57E+07 3.06E+07 - - - 9.009 1 221125_WJC_METTL3_EV_vs_WT_F05.16888.16888.3 6.10E-06 16/60 K.QFNYTHIC[160.03]AGASAFGK.N "sp|P13804|ETFA_HUMAN,tr|H0YL12|H0YL12_HUMAN,tr|H0YKF0|H0YKF0_HUMAN,tr|H0YLU7|H0YLU7_HUMAN,tr|H0YNX6|H0YNX6_HUMAN" 5 1770.8148 1.18 68239 16888 3 1770.816694 591.2789 "Electron transfer flavoprotein subunit alpha, mitochondrial OS=Homo sapiens OX=9606 GN=ETFA PE=1 SV=1" 8.21 2919.3 - 1.30E+06 - - - 1.0758 - 2.655 0.502 - 261.5 1 2 0 0.0019 16 0 0 0 1.47E+07 1.25E+07 - - - 6.6417 1 221125_WJC_METTL3_EV_vs_WT_F05.16892.16892.3 2.06E-09 22/76 R.MLWGSDPYPHAEPQQATTPK.A "sp|Q9Y520|PRC2C_HUMAN,tr|E7EPN9|E7EPN9_HUMAN" 2 2253.0525 1.12 68243 16892 3 2253.052362 752.0248 Protein PRRC2C OS=Homo sapiens OX=9606 GN=PRRC2C PE=1 SV=4 5.3 2919.8 - 926713 - - - -0.0404 - 4.003 0.66 - 478.3 1 2 0 -0.0001 20 0 0 0 3.58E+07 3.21E+07 - - - 9.2633 1 221125_WJC_METTL3_EV_vs_WT_F05.16897.16897.3 7.96E-09 20/76 R.MLWGSDPYPHAEPQQATTPK[136.11].A "sp|Q9Y520|PRC2C_HUMAN,tr|E7EPN9|E7EPN9_HUMAN" 2 2261.0667 1.12 68246 16897 3 2261.063262 754.6962 Protein PRRC2C OS=Homo sapiens OX=9606 GN=PRRC2C PE=1 SV=4 5.3 2920.4 - 1.67E+06 - - - -1.4997 - 3.598 0.613 - 271.4 1 2 0 -0.0034 20 0 0 0 3.58E+07 3.21E+07 - - - 8.4796 0.9999 221125_WJC_METTL3_EV_vs_WT_F05.16898.16898.4 1.20E-06 14/90 K.LEEAEKEAELHLTYLK.S "sp|Q8ND24|RN214_HUMAN,tr|E9PN76|E9PN76_HUMAN" 2 1914.9939 3.49 68247 16898 4 1914.992452 479.7557 RING finger protein 214 OS=Homo sapiens OX=9606 GN=RNF214 PE=1 SV=2 4.64 2920.6 - 720243 - - - -0.7347 - 3.212 0.512 - 146.1 1 2 1 -0.0014 16 0 0 0 9.89E+06 2.84E+06 - - - 4.0931 0.9997 221125_WJC_METTL3_EV_vs_WT_F05.16899.16899.2 8.13E-05 15/30 K.DIQDSLTVSNEVQTAK[136.11].E sp|P47755|CAZA2_HUMAN 1 1754.8778 0.99 68248 16899 2 1754.87378 878.4462 F-actin-capping protein subunit alpha-2 OS=Homo sapiens OX=9606 GN=CAPZA2 PE=1 SV=3 4.03 2920.7 - 367325 - - - -2.2754 - 2.225 0.502 - 194.2 1 2 0 -0.004 16 0 0 0 7.49E+06 7.53E+06 - - - 4.7138 0.9999 221125_WJC_METTL3_EV_vs_WT_F05.16905.16905.3 0.000759 Dec-36 R.MVNHFIAEFK[136.11].R "sp|P11142|HSP7C_HUMAN,tr|A8K7Q2|A8K7Q2_HUMAN,tr|E9PKE3|E9PKE3_HUMAN,tr|E9PN89|E9PN89_HUMAN" 4 1242.6311 0.17 68252 16905 3 1242.632647 415.2176 Heat shock cognate 71 kDa protein OS=Homo sapiens OX=9606 GN=HSPA8 PE=1 SV=1 6.5 2921.5 - 554415 - - - 1.2731 - 2.189 0.405 - 201.9 1 2 0 0.0016 10 0 0 0 3.28E+06 1.89E+07 - - - 5.3429 1 221125_WJC_METTL3_EV_vs_WT_F05.16911.16911.3 6.94E-06 19/64 R.TFNTSTGGLLLPSDTKR.S "sp|P12956|XRCC6_HUMAN,tr|B1AHC9|B1AHC9_HUMAN" 2 1806.9476 1.04 68256 16911 3 1806.948127 603.3231 X-ray repair cross-complementing protein 6 OS=Homo sapiens OX=9606 GN=XRCC6 PE=1 SV=2 8.41 2922.2 - 1.84E+06 - - - 0.3038 - 3.335 0.512 - 292.5 1 2 0 0.0005 17 0 0 0 1.46E+08 1.40E+08 - - - 7.291 0.9999 221125_WJC_METTL3_EV_vs_WT_F05.16912.16912.3 0.00141 14/48 R.QGTTPPIWHLTDK[136.11].K "sp|P55265|DSRAD_HUMAN,tr|A0A3B3ITG9|A0A3B3ITG9_HUMAN,tr|A0A3B3IRQ9|A0A3B3IRQ9_HUMAN,tr|A0A3B3ISU1|A0A3B3ISU1_HUMAN,tr|A0A7P0Z4K3|A0A7P0Z4K3_HUMAN,tr|A0A7P0TA14|A0A7P0TA14_HUMAN,tr|A0A3B3ISX1|A0A3B3ISX1_HUMAN,tr|A0A7P0Z4F9|A0A7P0Z4F9_HUMAN" 8 1500.7816 0.78 68257 16912 3 1500.780578 501.2678 Double-stranded RNA-specific adenosine deaminase OS=Homo sapiens OX=9606 GN=ADAR PE=1 SV=4 6.74 2922.3 - 891523 - - - -0.6996 - 2.567 0.366 - 371.2 1 2 0 -0.0011 13 0 0 0 4.31E+07 5.56E+07 - - - 5.1763 1 221125_WJC_METTL3_EV_vs_WT_F05.16913.16913.3 0.000163 Nov-64 R.TFNTSTGGLLLPSDTK[136.11]R[166.11].S "sp|P12956|XRCC6_HUMAN,tr|B1AHC9|B1AHC9_HUMAN" 2 1824.97 1.05 68258 16913 3 1824.968559 609.3306 X-ray repair cross-complementing protein 6 OS=Homo sapiens OX=9606 GN=XRCC6 PE=1 SV=2 8.41 2922.3 - 2.13E+06 - - - -0.8159 - 2.518 0.523 - 91.7 1 2 0 -0.0015 17 0 0 0 1.47E+08 1.40E+08 - - - 6.7035 1 221125_WJC_METTL3_EV_vs_WT_F05.16917.16917.2 5.85E-12 13/32 K.SGQVYSFGC[160.03]NDEGALGR[166.11].D "sp|P18754|RCC1_HUMAN,tr|C9JQZ4|C9JQZ4_HUMAN,tr|C9J3R0|C9J3R0_HUMAN,tr|C9JMJ4|C9JMJ4_HUMAN,tr|C9JW69|C9JW69_HUMAN,tr|C9JRH2|C9JRH2_HUMAN" 6 1825.7929 0.63 68262 16917 2 1825.788227 913.9037 Regulator of chromosome condensation OS=Homo sapiens OX=9606 GN=RCC1 PE=1 SV=1 4.37 2922.8 - 349107 - - - -2.5496 - 2.904 0.728 - 445.3 1 2 0 -0.0047 17 0 0 0 6.85E+06 1.09E+07 - - - 7.0376 0.9999 221125_WJC_METTL3_EV_vs_WT_F05.16919.16919.3 0.0116 15/48 R.QGTTPPIWHLTDK.K "sp|P55265|DSRAD_HUMAN,tr|A0A3B3ITG9|A0A3B3ITG9_HUMAN,tr|A0A3B3IRQ9|A0A3B3IRQ9_HUMAN,tr|A0A3B3ISU1|A0A3B3ISU1_HUMAN,tr|A0A7P0Z4K3|A0A7P0Z4K3_HUMAN,tr|A0A7P0TA14|A0A7P0TA14_HUMAN,tr|A0A3B3ISX1|A0A3B3ISX1_HUMAN,tr|A0A7P0Z4F9|A0A7P0Z4F9_HUMAN" 8 1492.7674 0.78 68263 16919 3 1492.765689 498.5964 Double-stranded RNA-specific adenosine deaminase OS=Homo sapiens OX=9606 GN=ADAR PE=1 SV=4 6.74 2923 - 1.27E+06 - - - -1.165 - 2.708 0.381 - 421 1 2 0 -0.0017 13 0 0 0 4.31E+07 5.56E+07 - - - 5.4883 0.9875 221125_WJC_METTL3_EV_vs_WT_F05.16922.16922.4 0.155 Nov-90 R.ALVVEMSRPRPLNTWK.L "sp|Q96PK6|RBM14_HUMAN,tr|B8ZZ74|B8ZZ74_HUMAN,tr|F8WDX3|F8WDX3_HUMAN,tr|A0A0A0MSL8|A0A0A0MSL8_HUMAN,tr|A0A0A6YYI9|A0A0A6YYI9_HUMAN" 5 1896.0404 1.76 68265 16922 4 1896.040344 475.0174 RNA-binding protein 14 OS=Homo sapiens OX=9606 GN=RBM14 PE=1 SV=2 10.84 2923.4 - 508936 - - - -0.0148 - 2.266 0.181 - 87.3 1 2 0 0 16 0 0 0 2.30E+07 1.30E+07 - - - 1.0896 1 221125_WJC_METTL3_EV_vs_WT_F05.16925.16925.2 1.63E-10 14/32 R.TATANGFQMVTSGVQSK.A "sp|Q969V3|NCLN_HUMAN,tr|K7EMW4|K7EMW4_HUMAN,tr|K7ENM2|K7ENM2_HUMAN" 3 1725.8356 1.4 68268 16925 2 1725.832052 863.9251 Nicalin OS=Homo sapiens OX=9606 GN=NCLN PE=1 SV=2 8.41 2923.8 - 339071 - - - -2.0465 - 3.157 0.676 - 728 1 2 0 -0.0035 17 0 0 0 2.40E+06 1.71E+06 - - - 6.8592 1 221125_WJC_METTL3_EV_vs_WT_F05.16927.16927.3 0.00147 Sep-40 K.ADFC[160.03]IIHYAGK[136.11].V "sp|P35580|MYH10_HUMAN,sp|P35579|MYH9_HUMAN" 2 1301.6318 0.7 68270 16927 3 1301.630514 434.8845 Myosin-10 OS=Homo sapiens OX=9606 GN=MYH10 PE=1 SV=3 6.78 2924 - 271065 - - - -0.9826 - 1.844 0.525 - 99.5 1 2 0 -0.0013 11 0 0 0 3.01E+06 4.31E+06 - - - 6.1313 0.9997 221125_WJC_METTL3_EV_vs_WT_F05.16931.16931.3 0.00151 Sep-40 K.ADFC[160.03]IIHYAGK.V "sp|P35580|MYH10_HUMAN,sp|P35579|MYH9_HUMAN" 2 1293.6176 0.69 68272 16931 3 1293.619511 432.2131 Myosin-10 OS=Homo sapiens OX=9606 GN=MYH10 PE=1 SV=3 6.78 2924.4 - 207176 - - - 1.4827 - 1.651 0.409 - 92.3 1 2 0 0.0019 11 0 0 0 2.81E+06 4.07E+06 - - - 4.5238 1 221125_WJC_METTL3_EV_vs_WT_F05.16932.16932.2 1.01E-12 16/32 K.SGQVYSFGC[160.03]NDEGALGR.D "sp|P18754|RCC1_HUMAN,tr|C9JQZ4|C9JQZ4_HUMAN,tr|C9J3R0|C9J3R0_HUMAN,tr|C9JMJ4|C9JMJ4_HUMAN,tr|C9JW69|C9JW69_HUMAN,tr|C9JRH2|C9JRH2_HUMAN" 6 1815.7846 0.63 68273 16932 2 1815.783805 908.8996 Regulator of chromosome condensation OS=Homo sapiens OX=9606 GN=RCC1 PE=1 SV=1 4.37 2924.6 - 374632 - - - -0.4444 - 3.246 0.763 - 746.2 1 2 0 -0.0008 17 0 0 0 6.85E+06 1.09E+07 - - - 7.571 0.9778 221125_WJC_METTL3_EV_vs_WT_F05.16933.16933.3 6.26E-05 15/52 N.GNPITIFQER[166.11]DPSK[136.11].L sp|P04406|G3P_HUMAN 1 1618.8434 0.98 68274 16933 3 1618.845008 540.6217 Glyceraldehyde-3-phosphate dehydrogenase OS=Homo sapiens OX=9606 GN=GAPDH PE=1 SV=3 6.07 2924.7 - 855115 - - - 0.9995 - 2.592 0.45 - 317 1 1 1 0.0016 14 0 0 0 2.08E+07 2.11E+07 - - - 6.0877 1 221125_WJC_METTL3_EV_vs_WT_F05.16934.16934.3 0.000469 17/40 K.RVNILSDMHLR.S "sp|P51114|FXR1_HUMAN,tr|E7EU85|E7EU85_HUMAN,tr|E9PFF5|E9PFF5_HUMAN,tr|C9JZE0|C9JZE0_HUMAN,tr|C9JY20|C9JY20_HUMAN,tr|B4DXZ6|B4DXZ6_HUMAN" 6 1352.7347 1.29 68275 16934 3 1352.733236 451.9188 Fragile X mental retardation syndrome-related protein 1 OS=Homo sapiens OX=9606 GN=FXR1 PE=1 SV=3 9.61 2924.8 - 700824 - - - -1.0734 - 2.846 0.463 - 497 1 2 0 -0.0015 11 0 0 0 9.66E+06 7.47E+06 - - - 6.6729 0.9407 221125_WJC_METTL3_EV_vs_WT_F05.16935.16935.2 1.30E-08 16/28 K.QISNLQQSISDAEQR.G sp|P04264|K2C1_HUMAN 1 1715.8438 999 68276 16935 2 1716.838839 858.9292 "Keratin, type II cytoskeletal 1 OS=Homo sapiens OX=9606 GN=KRT1 PE=1 SV=6" 4.37 2924.9 - 465647 - - - 579.8884 - 2.769 0.581 - 837 1 2 0 0.995 15 0 0 0 2.07E+06 0.00E+00 - - - 5.5238 1 221125_WJC_METTL3_EV_vs_WT_F05.16937.16937.2 7.97E-13 16/32 R.TATANGFQMVTSGVQSK[136.11].A "sp|Q969V3|NCLN_HUMAN,tr|K7EMW4|K7EMW4_HUMAN,tr|K7ENM2|K7ENM2_HUMAN" 3 1733.8498 1.4 68278 16937 2 1733.852042 867.9322 Nicalin OS=Homo sapiens OX=9606 GN=NCLN PE=1 SV=2 8.41 2925.2 - 277424 - - - 1.3023 - 3.276 0.696 - 950.1 1 2 0 0.0023 17 0 0 0 2.40E+06 1.71E+06 - - - 7.0983 0.9999 221125_WJC_METTL3_EV_vs_WT_F05.16943.16943.3 0.000127 13/60 R.K[136.11]NEALAPPLLDAEPAR[166.11].G sp|Q10469|MGAT2_HUMAN 1 1721.9431 1.62 68282 16943 3 1721.941997 574.9883 "Alpha-1,6-mannosyl-glycoprotein 2-beta-N-acetylglucosaminyltransferase OS=Homo sapiens OX=9606 GN=MGAT2 PE=1 SV=1" 4.68 2925.9 - 1.41E+06 - - - -0.6429 - 2.073 0.437 - 126.2 1 2 0 -0.0011 16 0 0 0 1.07E+08 6.60E+07 - - - 5.2823 0.9997 221125_WJC_METTL3_EV_vs_WT_F05.16944.16944.4 1.18E-05 17/96 K.QVK[136.11]PYVEEGLHPQIIIR[166.11].A "sp|Q99832|TCPH_HUMAN,tr|F8WAM2|F8WAM2_HUMAN" 2 2036.1538 0.18 68283 16944 4 2036.155337 510.0457 T-complex protein 1 subunit eta OS=Homo sapiens OX=9606 GN=CCT7 PE=1 SV=2 6.76 2926 - 8.71E+06 - - - 0.7716 - 2.691 0.346 - 175.7 1 2 0 0.0016 17 0 0 0 8.58E+07 4.77E+08 - - - 2.5808 0.9996 221125_WJC_METTL3_EV_vs_WT_F05.16955.16955.3 1.88E-06 Nov-72 R.VDSANALANGLIAGGHAAR[166.11].A sp|O15020|SPTN2_HUMAN 1 1786.9314 1.37 68294 16955 3 1786.937845 596.6511 "Spectrin beta chain, non-erythrocytic 2 OS=Homo sapiens OX=9606 GN=SPTBN2 PE=1 SV=3" 6.71 2927.4 - 264171 - - - 3.6269 - 2.466 0.441 - 120.6 1 2 0 0.0065 19 0 0 0 6.98E+06 5.10E+06 - - - 5.6724 1 221125_WJC_METTL3_EV_vs_WT_F05.16956.16956.2 5.60E-09 13/28 K.SQAC[160.03]GGNLGSIEELR[166.11].G "sp|Q9Y6E0|STK24_HUMAN,tr|Q5JV99|Q5JV99_HUMAN,tr|B4DR80|B4DR80_HUMAN,tr|Q5JV98|Q5JV98_HUMAN,tr|H0Y630|H0Y630_HUMAN" 5 1599.755 0.14 68295 16956 2 1599.750272 800.8848 Serine\threonine-protein kinase 24 OS=Homo sapiens OX=9606 GN=STK24 PE=1 SV=1 4.53 2927.5 - 196018 - - - -2.9798 - 2.902 0.645 - 565.2 1 2 0 -0.0048 15 0 0 0 1.41E+06 1.02E+07 - - - 6.4228 1 221125_WJC_METTL3_EV_vs_WT_F05.16960.16960.2 2.95E-12 16/32 R.NVSSFPDDATSPLQENR.N "sp|P52292|IMA1_HUMAN,tr|J3QLL0|J3QLL0_HUMAN,tr|J3KS65|J3KS65_HUMAN,tr|A0A7I2V3Z3|A0A7I2V3Z3_HUMAN,tr|A0A7I2YQE1|A0A7I2YQE1_HUMAN,tr|A0A7I2V487|A0A7I2V487_HUMAN,tr|A0A7I2V351|A0A7I2V351_HUMAN" 7 1875.8599 1.31 68298 16960 2 1875.862162 938.9372 Importin subunit alpha-1 OS=Homo sapiens OX=9606 GN=KPNA2 PE=1 SV=1 4.03 2928 - 1.11E+06 - - - 1.2138 - 3.107 0.7 - 559.5 1 2 0 0.0023 17 0 0 0 5.39E+07 4.11E+07 - - - 6.9976 0.9999 221125_WJC_METTL3_EV_vs_WT_F05.16965.16965.2 1.09E-06 18-Oct K.NMQDMVEDYR.N sp|P04264|K2C1_HUMAN 1 1299.5224 999 68302 16965 2 1299.523216 650.7685 "Keratin, type II cytoskeletal 1 OS=Homo sapiens OX=9606 GN=KRT1 PE=1 SV=6" 4.03 2928.5 - 517681 - - - 0.6495 - 2.038 0.548 - 389.8 1 2 0 0.0008 10 0 0 0 1.61E+07 0.00E+00 - - - 5.0756 1 221125_WJC_METTL3_EV_vs_WT_F05.16966.16966.2 5.91E-10 18/32 K.SQIFSTASDNQPTVTIK[136.11].V "sp|P11021|BIP_HUMAN,tr|A0A7P0TB36|A0A7P0TB36_HUMAN,tr|A0A7P0TAI0|A0A7P0TAI0_HUMAN" 3 1843.9407 0.63 68303 16966 2 1843.941272 922.9776 Endoplasmic reticulum chaperone BiP OS=Homo sapiens OX=9606 GN=HSPA5 PE=1 SV=2 5.55 2928.7 - 491351 - - - 0.3059 - 3.408 0.639 - 697.3 1 2 0 0.0006 17 0 0 0 7.78E+07 1.24E+08 - - - 6.775 0.9998 221125_WJC_METTL3_EV_vs_WT_F05.16968.16968.3 3.95E-06 Nov-56 K.SLYDEVAAQGEVVRK.L "sp|P07814|SYEP_HUMAN,tr|V9GYZ6|V9GYZ6_HUMAN" 2 1662.8577 0.67 68305 16968 3 1662.861965 555.2932 Bifunctional glutamate\proline--tRNA ligase OS=Homo sapiens OX=9606 GN=EPRS1 PE=1 SV=5 4.68 2928.9 - 401631 - - - 2.5649 - 1.965 0.482 - 109.3 1 2 0 0.0043 15 0 0 0 3.32E+06 4.95E+06 - - - 5.6752 0.9993 221125_WJC_METTL3_EV_vs_WT_F05.16971.16971.2 1.93E-06 14/30 K.ALQDLENAASGDATVR.Q "sp|Q9NQG5|RPR1B_HUMAN,tr|A2A2M0|A2A2M0_HUMAN" 2 1629.7958 4.11 68308 16971 2 1629.801283 815.9052 Regulation of nuclear pre-mRNA domain-containing protein 1B OS=Homo sapiens OX=9606 GN=RPRD1B PE=1 SV=1 4.03 2929.3 - 223059 - - - 3.347 - 3.213 0.394 - 836.1 1 2 0 0.0055 16 0 0 0 1.72E+06 4.19E+05 - - - 4.819 1 221125_WJC_METTL3_EV_vs_WT_F05.16974.16974.2 1.17E-10 15/32 R.NVSSFPDDATSPLQENR[166.11].N "sp|P52292|IMA1_HUMAN,tr|J3QLL0|J3QLL0_HUMAN,tr|J3KS65|J3KS65_HUMAN,tr|A0A7I2V3Z3|A0A7I2V3Z3_HUMAN,tr|A0A7I2YQE1|A0A7I2YQE1_HUMAN,tr|A0A7I2V487|A0A7I2V487_HUMAN,tr|A0A7I2V351|A0A7I2V351_HUMAN" 7 1885.8682 1.25 68310 16974 2 1885.866441 943.9414 Importin subunit alpha-1 OS=Homo sapiens OX=9606 GN=KPNA2 PE=1 SV=1 4.03 2929.7 - 689299 - - - -0.9089 - 2.947 0.677 - 494.3 1 2 0 -0.0017 17 0 0 0 1.02E+08 8.21E+07 - - - 6.698 1 221125_WJC_METTL3_EV_vs_WT_F05.16976.16976.3 1.69E-06 20/64 K.QVK[136.11]PYVEEGLHPQIIIR[166.11].A "sp|Q99832|TCPH_HUMAN,tr|F8WAM2|F8WAM2_HUMAN" 2 2036.1538 0.17 68312 16976 3 2036.155624 679.7252 T-complex protein 1 subunit eta OS=Homo sapiens OX=9606 GN=CCT7 PE=1 SV=2 6.76 2929.7 - 5.45E+06 - - - 0.9125 - 3.651 0.489 - 440.6 1 2 0 0.0019 17 0 0 0 2.06E+07 1.19E+08 - - - 7.2629 1 221125_WJC_METTL3_EV_vs_WT_F05.16977.16977.2 7.99E-08 17/32 K.SQIFSTASDNQPTVTIK.V "sp|P11021|BIP_HUMAN,tr|A0A7P0TB36|A0A7P0TB36_HUMAN,tr|A0A7P0TAI0|A0A7P0TAI0_HUMAN" 3 1835.9265 0.63 68313 16977 2 1835.928119 918.9705 Endoplasmic reticulum chaperone BiP OS=Homo sapiens OX=9606 GN=HSPA5 PE=1 SV=2 5.55 2929.9 - 658747 - - - 0.8775 - 3.084 0.595 - 425.5 1 2 0 0.0016 17 0 0 0 7.78E+07 1.24E+08 - - - 6.204 0.9999 221125_WJC_METTL3_EV_vs_WT_F05.16978.16978.3 0.00023 16/60 K.QTALLDADDPVSQLHK.C "sp|Q06330|SUH_HUMAN,tr|A0A7P0Z4N7|A0A7P0Z4N7_HUMAN,tr|D6RF98|D6RF98_HUMAN,tr|H0Y8R3|H0Y8R3_HUMAN,tr|D6R927|D6R927_HUMAN,tr|A0A7P0T9Y9|A0A7P0T9Y9_HUMAN,tr|A0A7P0T947|A0A7P0T947_HUMAN,tr|A0A7P0TBJ4|A0A7P0TBJ4_HUMAN" 8 1749.8897 0.7 68314 16978 3 1749.894048 584.3039 Recombining binding protein suppressor of hairless OS=Homo sapiens OX=9606 GN=RBPJ PE=1 SV=3 4.41 2930 - 434623 - - - 2.4687 - 2.899 0.443 - 349.8 1 2 0 0.0043 16 0 0 0 6.23E+06 8.86E+06 - - - 6.2088 1 221125_WJC_METTL3_EV_vs_WT_F05.16980.16980.3 2.57E-07 14/76 R.QLIIVHGPPEASQDLAEC[160.03]C[160.03]R[166.11].A "sp|Q9P2I0|CPSF2_HUMAN,tr|H0YJF4|H0YJF4_HUMAN" 2 2302.1074 1.14 68316 16980 3 2302.112637 768.3764 Cleavage and polyadenylation specificity factor subunit 2 OS=Homo sapiens OX=9606 GN=CPSF2 PE=1 SV=2 4.65 2930.3 - 225848 - - - 2.2936 - 2.683 0.602 - 154.3 1 2 0 0.0053 20 0 0 0 4.08E+06 3.59E+06 - - - 7.6446 0.9999 221125_WJC_METTL3_EV_vs_WT_F05.16981.16981.3 0.000189 Nov-44 R.SSTFSDVEAHFR.A sp|Q8ND82|Z280C_HUMAN 1 1381.6262 1.23 68317 16981 3 1381.626823 461.5494 Zinc finger protein 280C OS=Homo sapiens OX=9606 GN=ZNF280C PE=1 SV=1 5.3 2930.4 - 165873 - - - 0.4198 - 1.824 0.445 - 169.3 1 2 0 0.0006 12 0 0 0 4.26E+06 3.47E+06 - - - 5.1671 0.9999 221125_WJC_METTL3_EV_vs_WT_F05.16983.16983.2 1.42E-05 30-Nov K.ATANSLVSSEWGNPSR.N "sp|Q96AV8|E2F7_HUMAN,tr|F8VSE7|F8VSE7_HUMAN" 2 1674.7962 1.15 68319 16983 2 1674.79679 838.4054 Transcription factor E2F7 OS=Homo sapiens OX=9606 GN=E2F7 PE=1 SV=3 6.05 2930.7 - 142767 - - - 0.375 - 2.287 0.543 - 290.8 1 2 0 0.0006 16 0 0 0 1.81E+06 1.57E+06 - - - 5.0852 0.9999 221125_WJC_METTL3_EV_vs_WT_F05.16986.16986.4 1.96E-06 15/96 K.QVKPYVEEGLHPQIIIR.A "sp|Q99832|TCPH_HUMAN,tr|F8WAM2|F8WAM2_HUMAN" 2 2018.1313 0.18 68320 16986 4 2018.13426 505.5401 T-complex protein 1 subunit eta OS=Homo sapiens OX=9606 GN=CCT7 PE=1 SV=2 6.76 2931.1 - 5.59E+06 - - - 1.4687 - 2.949 0.415 - 152.1 1 2 0 0.003 17 0 0 0 8.57E+07 4.76E+08 - - - 3.2128 0.9995 221125_WJC_METTL3_EV_vs_WT_F05.16987.16987.3 0.000419 Nov-48 K.DTDSEEEIR[166.11]EAFR[166.11].V "sp|P0DP25|CALM3_HUMAN,sp|P0DP23|CALM1_HUMAN,sp|P0DP24|CALM2_HUMAN,tr|G3V361|G3V361_HUMAN,tr|A0A590UJI2|A0A590UJI2_HUMAN,tr|Q96HY3|Q96HY3_HUMAN,tr|A0A590UJC0|A0A590UJC0_HUMAN,tr|G3V226|G3V226_HUMAN,tr|E7EMB3|E7EMB3_HUMAN" 9 1615.7229 1.22 68321 16987 3 1615.724562 539.5816 Calmodulin-3 OS=Homo sapiens OX=9606 GN=CALM3 PE=1 SV=1 4.08 2931.2 - 1.03E+06 - - - 1.0385 - 2.039 0.429 - 195.6 1 2 1 0.0017 13 0 0 0 3.14E+07 2.57E+07 - - - 5.2541 0.998 221125_WJC_METTL3_EV_vs_WT_F05.16988.16988.3 0.0317 13/48 K.DTDSEEEIREAFR.V "sp|P0DP25|CALM3_HUMAN,sp|P0DP23|CALM1_HUMAN,sp|P0DP24|CALM2_HUMAN,tr|G3V361|G3V361_HUMAN,tr|A0A590UJI2|A0A590UJI2_HUMAN,tr|Q96HY3|Q96HY3_HUMAN,tr|A0A590UJC0|A0A590UJC0_HUMAN,tr|G3V226|G3V226_HUMAN,tr|E7EMB3|E7EMB3_HUMAN" 9 1595.7063 1.22 68322 16988 3 1595.706506 532.9094 Calmodulin-3 OS=Homo sapiens OX=9606 GN=CALM3 PE=1 SV=1 4.08 2931.3 - 801612 - - - 0.1015 - 2.075 0.306 - 273.5 1 2 1 0.0002 13 0 0 0 3.10E+07 2.55E+07 - - - 3.9307 0.9998 221125_WJC_METTL3_EV_vs_WT_F05.16992.16992.3 0.0011 14/72 R.VDSANALANGLIAGGHAAR.A sp|O15020|SPTN2_HUMAN 1 1776.9231 1.37 68326 16992 3 1776.925847 593.315 "Spectrin beta chain, non-erythrocytic 2 OS=Homo sapiens OX=9606 GN=SPTBN2 PE=1 SV=3" 6.71 2931.8 - 611231 - - - 1.5493 - 2.241 0.389 - 97.7 1 2 0 0.0028 19 0 0 0 6.98E+06 5.10E+06 - - - 4.8587 1 221125_WJC_METTL3_EV_vs_WT_F05.16994.16994.3 7.73E-06 Nov-64 R.NVSSFPDDATSPLQENR.N "sp|P52292|IMA1_HUMAN,tr|J3QLL0|J3QLL0_HUMAN,tr|J3KS65|J3KS65_HUMAN,tr|A0A7I2V3Z3|A0A7I2V3Z3_HUMAN,tr|A0A7I2YQE1|A0A7I2YQE1_HUMAN,tr|A0A7I2V487|A0A7I2V487_HUMAN,tr|A0A7I2V351|A0A7I2V351_HUMAN" 7 1875.8599 0.59 68328 16994 3 1875.862038 626.2939 Importin subunit alpha-1 OS=Homo sapiens OX=9606 GN=KPNA2 PE=1 SV=1 4.03 2932 - 552896 - - - 1.1477 - 2.149 0.584 - 155.7 1 2 0 0.0022 17 0 0 0 1.37E+07 2.34E+07 - - - 6.9831 1 221125_WJC_METTL3_EV_vs_WT_F05.17001.17001.3 1.76E-05 21/64 K.QVKPYVEEGLHPQIIIR.A "sp|Q99832|TCPH_HUMAN,tr|F8WAM2|F8WAM2_HUMAN" 2 2018.1313 0.17 68333 17001 3 2018.134856 673.7177 T-complex protein 1 subunit eta OS=Homo sapiens OX=9606 GN=CCT7 PE=1 SV=2 6.76 2932.9 - 1.31E+06 - - - 1.764 - 3.541 0.498 - 481.9 1 2 0 0.0036 17 0 0 0 2.06E+07 1.19E+08 - - - 7.2855 1 221125_WJC_METTL3_EV_vs_WT_F05.17002.17002.3 1.45E-08 17/84 R.AGAIAPC[160.03]EVTVPAQNTGLGPEK[136.11].T "sp|Q8NHW5|RLA0L_HUMAN,sp|P05388|RLA0_HUMAN,tr|G3V210|G3V210_HUMAN,tr|F8VU65|F8VU65_HUMAN,tr|F8VWS0|F8VWS0_HUMAN,tr|F8VW21|F8VW21_HUMAN,tr|F8VRK7|F8VRK7_HUMAN,tr|F8VQY6|F8VQY6_HUMAN,tr|F8VPE8|F8VPE8_HUMAN" 9 2187.1085 0.96 68334 17002 3 2187.109814 730.0434 60S acidic ribosomal protein P0-like OS=Homo sapiens OX=9606 GN=RPLP0P6 PE=5 SV=1 4.53 2933 - 652387 - - - 0.5921 - 3.016 0.517 - 259.8 1 2 0 0.0013 22 0 0 0 1.81E+08 1.88E+08 - - - 6.9209 1 221125_WJC_METTL3_EV_vs_WT_F05.17003.17003.3 1.73E-09 16/60 K.QTALLDADDPVSQLHK[136.11].C "sp|Q06330|SUH_HUMAN,tr|A0A7P0Z4N7|A0A7P0Z4N7_HUMAN,tr|D6RF98|D6RF98_HUMAN,tr|H0Y8R3|H0Y8R3_HUMAN,tr|D6R927|D6R927_HUMAN,tr|A0A7P0T9Y9|A0A7P0T9Y9_HUMAN,tr|A0A7P0T947|A0A7P0T947_HUMAN,tr|A0A7P0TBJ4|A0A7P0TBJ4_HUMAN" 8 1757.9039 0.73 68335 17003 3 1757.90521 586.9753 Recombining binding protein suppressor of hairless OS=Homo sapiens OX=9606 GN=RBPJ PE=1 SV=3 4.41 2933.1 - 575633 - - - 0.7293 - 3.221 0.567 - 386.9 1 2 0 0.0013 16 0 0 0 6.49E+06 8.86E+06 - - - 7.8624 0.9997 221125_WJC_METTL3_EV_vs_WT_F05.17006.17006.3 0.00211 Aug-32 K.FYVHNDIFR[166.11].Y "sp|Q13283|G3BP1_HUMAN,tr|A0A7I2V5M7|A0A7I2V5M7_HUMAN,tr|A0A7P0P2U7|A0A7P0P2U7_HUMAN,tr|A0A7I2YQU8|A0A7I2YQU8_HUMAN,tr|A0A7I2V651|A0A7I2V651_HUMAN,tr|A0A7I2YQN9|A0A7I2YQN9_HUMAN,tr|A0A7I2V2V1|A0A7I2V2V1_HUMAN" 7 1219.6014 1.86 68338 17006 3 1219.60171 407.5411 Ras GTPase-activating protein-binding protein 1 OS=Homo sapiens OX=9606 GN=G3BP1 PE=1 SV=1 6.74 2933.5 - 239738 - - - 0.2845 - 1.639 0.367 - 69.6 1 2 0 0.0003 9 0 0 0 6.43E+06 3.47E+06 - - - 4.1207 0.9999 221125_WJC_METTL3_EV_vs_WT_F05.17007.17007.2 5.86E-07 Jul-32 R.TFNTSTGGLLLPSDTKR.S "sp|P12956|XRCC6_HUMAN,tr|B1AHC9|B1AHC9_HUMAN" 2 1806.9476 1.16 68339 17007 2 1806.949431 904.4811 X-ray repair cross-complementing protein 6 OS=Homo sapiens OX=9606 GN=XRCC6 PE=1 SV=2 8.41 2933.6 - 173307 - - - 1.0255 - 2.027 0.588 - 94.8 1 2 0 0.0019 17 0 0 0 2.61E+06 2.25E+06 - - - 5.1205 0.9999 221125_WJC_METTL3_EV_vs_WT_F05.17009.17009.2 8.09E-07 Sep-32 R.TFNTSTGGLLLPSDTK[136.11]R[166.11].S "sp|P12956|XRCC6_HUMAN,tr|B1AHC9|B1AHC9_HUMAN" 2 1824.97 1.16 68341 17009 2 1824.97082 913.4923 X-ray repair cross-complementing protein 6 OS=Homo sapiens OX=9606 GN=XRCC6 PE=1 SV=2 8.41 2933.9 - 103173 - - - 0.423 - 2.049 0.62 - 180.5 1 2 0 0.0008 17 0 0 0 2.61E+06 2.25E+06 - - - 5.3837 1 221125_WJC_METTL3_EV_vs_WT_F05.17013.17013.3 2.31E-11 20/84 R.AGAIAPC[160.03]EVTVPAQNTGLGPEK.T "sp|Q8NHW5|RLA0L_HUMAN,sp|P05388|RLA0_HUMAN,tr|G3V210|G3V210_HUMAN,tr|F8VU65|F8VU65_HUMAN,tr|F8VWS0|F8VWS0_HUMAN,tr|F8VW21|F8VW21_HUMAN,tr|F8VRK7|F8VRK7_HUMAN,tr|F8VQY6|F8VQY6_HUMAN,tr|F8VPE8|F8VPE8_HUMAN" 9 2179.0943 0.97 68343 17013 3 2179.095103 727.372 60S acidic ribosomal protein P0-like OS=Homo sapiens OX=9606 GN=RPLP0P6 PE=5 SV=1 4.53 2934.4 - 1.89E+06 - - - 0.3598 - 3.728 0.627 - 399.9 1 2 0 0.0008 22 0 0 0 1.81E+08 1.86E+08 - - - 8.6499 0.8085 221125_WJC_METTL3_EV_vs_WT_F05.17017.17017.3 0.000132 13/56 K.QISNLQQSISDAEQR.G sp|P04264|K2C1_HUMAN 1 1715.8438 999 68347 17017 3 1716.834587 572.9552 "Keratin, type II cytoskeletal 1 OS=Homo sapiens OX=9606 GN=KRT1 PE=1 SV=6" 4.37 2934.9 - 565682 - - - 577.4104 - 2.257 0.427 - 192.8 1 2 0 0.9907 15 0 0 0 2.49E+06 0.00E+00 - - - 5.1503 0.9999 221125_WJC_METTL3_EV_vs_WT_F05.17024.17024.2 6.99E-07 Jul-32 K.TLNFEDQTSTDNVSITK[136.11].D "sp|O60293|ZC3H1_HUMAN,tr|G3V1X1|G3V1X1_HUMAN" 2 1919.9204 0.84 68354 17024 2 1919.920963 960.9675 Zinc finger C3H1 domain-containing protein OS=Homo sapiens OX=9606 GN=ZFC3H1 PE=1 SV=3 4.03 2935.8 - 182512 - - - 0.311 - 1.896 0.612 - 112.1 1 2 0 0.0006 17 0 0 0 1.70E+06 2.02E+06 - - - 5.1339 0.9819 221125_WJC_METTL3_EV_vs_WT_F05.17026.17026.3 0.00509 Jul-40 R.SK[136.11]TDLDC[160.03]IFGK[136.11].R "sp|Q96BK5|PINX1_HUMAN,tr|E5RGR1|E5RGR1_HUMAN" 2 1298.6511 0.84 68356 17026 3 1298.65141 433.891 PIN2\TERF1-interacting telomerase inhibitor 1 OS=Homo sapiens OX=9606 GN=PINX1 PE=1 SV=2 5.68 2936.1 - 140551 - - - 0.2094 - 1.622 0.221 - 51.3 1 2 1 0.0003 11 0 0 0 2.07E+06 2.45E+06 - - - 2.3779 1 221125_WJC_METTL3_EV_vs_WT_F05.17030.17030.3 2.46E-09 18/68 R.FGAQQDTIEVPEK[136.11]DLVDK[136.11].A "sp|P49736|MCM2_HUMAN,tr|H0Y8E6|H0Y8E6_HUMAN" 2 2047.0445 1.34 68358 17030 3 2047.045504 683.3554 DNA replication licensing factor MCM2 OS=Homo sapiens OX=9606 GN=MCM2 PE=1 SV=4 4.11 2936.6 - 997503 - - - 0.5144 - 3.185 0.601 - 330.9 1 2 1 0.0011 18 0 0 0 1.57E+07 1.17E+07 - - - 8.1249 1 221125_WJC_METTL3_EV_vs_WT_F05.17031.17031.2 8.34E-11 18/42 R.AGAIAPC[160.03]EVTVPAQNTGLGPEK[136.11].T "sp|Q8NHW5|RLA0L_HUMAN,sp|P05388|RLA0_HUMAN,tr|G3V210|G3V210_HUMAN,tr|F8VU65|F8VU65_HUMAN,tr|F8VWS0|F8VWS0_HUMAN,tr|F8VW21|F8VW21_HUMAN,tr|F8VRK7|F8VRK7_HUMAN,tr|F8VQY6|F8VQY6_HUMAN,tr|F8VPE8|F8VPE8_HUMAN" 9 2187.1085 1.26 68359 17031 2 2187.109184 1094.5615 60S acidic ribosomal protein P0-like OS=Homo sapiens OX=9606 GN=RPLP0P6 PE=5 SV=1 4.53 2936.8 - 855511 - - - 0.3041 - 3.15 0.677 - 489 1 2 0 0.0007 22 0 0 0 2.35E+07 1.88E+07 - - - 6.8621 1 221125_WJC_METTL3_EV_vs_WT_F05.17032.17032.2 1.51E-12 20/42 R.AGAIAPC[160.03]EVTVPAQNTGLGPEK.T "sp|Q8NHW5|RLA0L_HUMAN,sp|P05388|RLA0_HUMAN,tr|G3V210|G3V210_HUMAN,tr|F8VU65|F8VU65_HUMAN,tr|F8VWS0|F8VWS0_HUMAN,tr|F8VW21|F8VW21_HUMAN,tr|F8VRK7|F8VRK7_HUMAN,tr|F8VQY6|F8VQY6_HUMAN,tr|F8VPE8|F8VPE8_HUMAN" 9 2179.0943 1.26 68360 17032 2 2179.096631 1090.5544 60S acidic ribosomal protein P0-like OS=Homo sapiens OX=9606 GN=RPLP0P6 PE=5 SV=1 4.53 2936.9 - 677669 - - - 1.061 - 3.179 0.67 - 565.1 1 2 0 0.0023 22 0 0 0 2.35E+07 1.88E+07 - - - 6.8324 0.9999 221125_WJC_METTL3_EV_vs_WT_F05.17034.17034.3 0.000626 Aug-32 K.FYVHNDIFR.Y "sp|Q13283|G3BP1_HUMAN,tr|A0A7I2V5M7|A0A7I2V5M7_HUMAN,tr|A0A7P0P2U7|A0A7P0P2U7_HUMAN,tr|A0A7I2YQU8|A0A7I2YQU8_HUMAN,tr|A0A7I2V651|A0A7I2V651_HUMAN,tr|A0A7I2YQN9|A0A7I2YQN9_HUMAN,tr|A0A7I2V2V1|A0A7I2V2V1_HUMAN" 7 1209.5931 1.6 68362 17034 3 1209.592768 404.205 Ras GTPase-activating protein-binding protein 1 OS=Homo sapiens OX=9606 GN=G3BP1 PE=1 SV=1 6.74 2937.2 - 474876 - - - -0.2687 - 1.711 0.45 - 88.5 1 2 0 -0.0003 9 0 0 0 5.54E+06 3.47E+06 - - - 5.1756 1 221125_WJC_METTL3_EV_vs_WT_F05.17037.17037.3 2.54E-10 20/76 R.VPFSPGPAPPPHMGELDQER.L "sp|Q6Y7W6|GGYF2_HUMAN,tr|A0A7I2V3H7|A0A7I2V3H7_HUMAN,tr|I1E4Y6|I1E4Y6_HUMAN,tr|A0A7I2V516|A0A7I2V516_HUMAN,tr|A0A7I2V3H0|A0A7I2V3H0_HUMAN,tr|C9JHW1|C9JHW1_HUMAN,tr|A0A7I2V361|A0A7I2V361_HUMAN,tr|E7ESB6|E7ESB6_HUMAN" 8 2157.0313 4.38 68365 17037 3 2157.035939 720.0177 GRB10-interacting GYF protein 2 OS=Homo sapiens OX=9606 GN=GIGYF2 PE=1 SV=1 4.65 2937.6 - 271720 - - - 2.1395 - 3.576 0.6 - 376.6 1 2 0 0.0046 20 0 0 0 7.67E+07 1.75E+07 - - - 8.3195 0.9999 221125_WJC_METTL3_EV_vs_WT_F05.17043.17043.3 0.0019 18/48 R.NSDLLLLVDTHKK.Q sp|Q6P4E1|GOLM2_HUMAN 1 1494.8406 1.64 68369 17043 3 1494.841774 499.2875 Protein GOLM2 OS=Homo sapiens OX=9606 GN=GOLM2 PE=1 SV=2 6.75 2938.4 - 611613 - - - 0.7901 - 2.939 0.374 - 466.6 1 2 0 0.0012 13 0 0 0 7.02E+06 4.28E+06 - - - 5.6324 0.9966 221125_WJC_METTL3_EV_vs_WT_F05.17046.17046.3 1.31E-06 20/72 F.K[136.11]VGINYQPPTVVPGGDLAK[136.11].V "sp|Q9NY65|TBA8_HUMAN,sp|Q6PEY2|TBA3E_HUMAN,sp|P0DPH7|TBA3C_HUMAN,sp|Q71U36|TBA1A_HUMAN,sp|P0DPH8|TBA3D_HUMAN,sp|P68366|TBA4A_HUMAN,sp|P68363|TBA1B_HUMAN,sp|Q9BQE3|TBA1C_HUMAN,tr|A0A1W2PQM2|A0A1W2PQM2_HUMAN,tr|F5H5D3|F5H5D3_HUMAN,tr|C9J2C0|C9J2C0_HUMAN,tr|V9GZ17|V9GZ17_HUMAN,tr|A0A7P0T945|A0A7P0T945_HUMAN" 13 1968.1015 0.74 68372 17046 3 1968.106086 657.0411 Tubulin alpha-8 chain OS=Homo sapiens OX=9606 GN=TUBA8 PE=1 SV=1 8.5 2938.6 - 757747 - - - 2.3241 - 3.718 0.53 - 350.7 1 1 0 0.0046 19 0 0 0 9.43E+06 1.27E+07 - - - 7.6739 1 221125_WJC_METTL3_EV_vs_WT_F05.17048.17048.3 1.01E-08 20/76 R.AAYLNMSEDPSHPSMALNTR[166.11].F "sp|Q14839|CHD4_HUMAN,tr|A0A2R8Y4X2|A0A2R8Y4X2_HUMAN,tr|A0A2U3TZM0|A0A2U3TZM0_HUMAN,tr|A0A2R8YD40|A0A2R8YD40_HUMAN,tr|A0A2R8Y5J0|A0A2R8Y5J0_HUMAN,tr|A0A2R8Y425|A0A2R8Y425_HUMAN,tr|A0A2R8YFK9|A0A2R8YFK9_HUMAN,tr|A0A0C4DGG9|A0A0C4DGG9_HUMAN,tr|A0A2R8YFD8|A0A2R8YFD8_HUMAN,tr|A0A2R8YDW2|A0A2R8YDW2_HUMAN,tr|A0A2R8Y7I0|A0A2R8Y7I0_HUMAN,tr|F5GWX5|F5GWX5_HUMAN,tr|A0A2R8Y7M9|A0A2R8Y7M9_HUMAN,tr|A0A2R8Y521|A0A2R8Y521_HUMAN,tr|A0A2R8YDJ9|A0A2R8YDJ9_HUMAN,tr|A0A2R8Y212|A0A2R8Y212_HUMAN" 16 2214.0073 1.02 68374 17048 3 2214.007606 739.0097 Chromodomain-helicase-DNA-binding protein 4 OS=Homo sapiens OX=9606 GN=CHD4 PE=1 SV=2 5.32 2938.9 - 515335 - - - 0.1346 - 3.064 0.583 - 375.3 1 2 0 0.0003 20 0 0 0 4.60E+06 4.52E+06 - - - 7.7563 0.9999 221125_WJC_METTL3_EV_vs_WT_F05.17049.17049.2 9.98E-05 17/28 R.STQGVTLTDLQEAEK[136.11].T "sp|O14974|MYPT1_HUMAN,tr|F8VZN8|F8VZN8_HUMAN,tr|H0YHI8|H0YHI8_HUMAN,tr|H0YIS4|H0YIS4_HUMAN,tr|A0A3B3ISH4|A0A3B3ISH4_HUMAN" 5 1626.8192 0.85 68375 17049 2 1626.819412 814.4169 Protein phosphatase 1 regulatory subunit 12A OS=Homo sapiens OX=9606 GN=PPP1R12A PE=1 SV=1 4.14 2939 - 509094 - - - 0.1328 - 2.91 0.506 - 821 1 2 0 0.0002 15 0 0 0 3.64E+06 4.30E+06 - - - 5.4044 0.9979 221125_WJC_METTL3_EV_vs_WT_F05.17050.17050.3 0.00179 Nov-60 R.QATK[136.11]DAGTIAGLNVLR[166.11].L "sp|P11142|HSP7C_HUMAN,tr|E9PQQ4|E9PQQ4_HUMAN,tr|E9PN89|E9PN89_HUMAN,tr|E9PLF4|E9PLF4_HUMAN,tr|E9PI65|E9PI65_HUMAN,tr|E9PK54|E9PK54_HUMAN,tr|E9PQK7|E9PQK7_HUMAN" 7 1644.9278 0.21 68376 17050 3 1644.928326 549.3165 Heat shock cognate 71 kDa protein OS=Homo sapiens OX=9606 GN=HSPA8 PE=1 SV=1 8.75 2939.1 - 447784 - - - 0.3265 - 2.174 0.3 - 178.1 1 2 1 0.0005 16 0 0 0 7.52E+05 3.64E+06 - - - 3.8771 0.9956 221125_WJC_METTL3_EV_vs_WT_F05.17051.17051.3 7.42E-07 20/72 F.KVGINYQPPTVVPGGDLAK.V "sp|Q9NY65|TBA8_HUMAN,sp|Q6PEY2|TBA3E_HUMAN,sp|P0DPH7|TBA3C_HUMAN,sp|Q71U36|TBA1A_HUMAN,sp|P0DPH8|TBA3D_HUMAN,sp|P68366|TBA4A_HUMAN,sp|P68363|TBA1B_HUMAN,sp|Q9BQE3|TBA1C_HUMAN,tr|A0A1W2PQM2|A0A1W2PQM2_HUMAN,tr|F5H5D3|F5H5D3_HUMAN,tr|C9J2C0|C9J2C0_HUMAN,tr|V9GZ17|V9GZ17_HUMAN,tr|A0A7P0T945|A0A7P0T945_HUMAN" 13 1952.0731 0.74 68377 17051 3 1952.078643 651.6983 Tubulin alpha-8 chain OS=Homo sapiens OX=9606 GN=TUBA8 PE=1 SV=1 8.5 2939.3 - 412161 - - - 2.8334 - 3.73 0.547 - 295.3 1 1 0 0.0055 19 0 0 0 9.67E+06 1.31E+07 - - - 7.8711 0.9697 221125_WJC_METTL3_EV_vs_WT_F05.17052.17052.2 0.000356 28-Nov K.SQGLSQLYHNQSQGL.L "sp|P78344|IF4G2_HUMAN,tr|D3DQV9|D3DQV9_HUMAN" 2 1658.8012 - 68378 17052 2 1658.805223 830.4079 Eukaryotic translation initiation factor 4 gamma 2 OS=Homo sapiens OX=9606 GN=EIF4G2 PE=1 SV=1 6.46 2939.4 - 380410 - - - 2.3963 - 2.49 0.407 - 233.3 1 1 0 0.004 15 0 0 0 - - - - - 4.2887 0.9999 221125_WJC_METTL3_EV_vs_WT_F05.17053.17053.2 0.000545 14/28 R.STQGVTLTDLQEAEK.T "sp|O14974|MYPT1_HUMAN,tr|F8VZN8|F8VZN8_HUMAN,tr|H0YHI8|H0YHI8_HUMAN,tr|H0YIS4|H0YIS4_HUMAN,tr|A0A3B3ISH4|A0A3B3ISH4_HUMAN" 5 1618.805 0.85 68379 17053 2 1618.805892 810.4098 Protein phosphatase 1 regulatory subunit 12A OS=Homo sapiens OX=9606 GN=PPP1R12A PE=1 SV=1 4.14 2939.5 - 332737 - - - 0.5535 - 2.759 0.5 - 677.9 1 2 0 0.0009 15 0 0 0 3.64E+06 4.30E+06 - - - 5.2288 0.9556 221125_WJC_METTL3_EV_vs_WT_F05.17059.17059.2 0.000641 Dec-34 K.KPGAGDTAFPGTGGFSAT.F sp|Q96PK6|RBM14_HUMAN 1 1637.7686 1.76 68383 17059 2 1637.76508 819.8916 RNA-binding protein 14 OS=Homo sapiens OX=9606 GN=RBM14 PE=1 SV=2 5.84 2940.2 - 690696 - - - -2.1187 - 2.339 0.317 - 218.7 1 1 0 -0.0035 18 0 0 0 1.28E+07 7.27E+06 - - - 3.4704 0.9997 221125_WJC_METTL3_EV_vs_WT_F05.17060.17060.3 0.000616 Nov-40 K.ALNSIIDVYHK.Y sp|P05109|S10A8_HUMAN 1 1271.6874 999 68384 17060 3 1271.688061 424.9031 Protein S100-A8 OS=Homo sapiens OX=9606 GN=S100A8 PE=1 SV=1 6.79 2940.4 - 677927 - - - 0.53 - 2.137 0.319 - 160.4 1 2 0 0.0007 11 0 0 0 9.68E+06 0.00E+00 - - - 4.2537 1 221125_WJC_METTL3_EV_vs_WT_F05.17061.17061.3 1.51E-12 30/88 R.GNFGGSFAGSFGGAGGHAPGVAR[166.11].K "sp|P52272|HNRPM_HUMAN,tr|M0R2I7|M0R2I7_HUMAN,tr|M0QY96|M0QY96_HUMAN,tr|A0A087X0X3|A0A087X0X3_HUMAN" 4 2043.9539 1.78 68385 17061 3 2043.955207 682.3252 Heterogeneous nuclear ribonucleoprotein M OS=Homo sapiens OX=9606 GN=HNRNPM PE=1 SV=3 9.76 2940.5 - 1.29E+06 - - - 0.6443 - 4.972 0.666 - 1162.2 1 2 0 0.0013 23 0 0 0 1.68E+08 9.43E+07 - - - 9.7274 1 221125_WJC_METTL3_EV_vs_WT_F05.17062.17062.3 5.05E-07 21/68 R.R[166.11]SLGYAYVNFQQPADAER[166.11].A "sp|Q13310|PABP4_HUMAN,sp|P11940|PABP1_HUMAN,tr|A0A7I2V649|A0A7I2V649_HUMAN,tr|B1ANR0|B1ANR0_HUMAN,tr|A0A7I2V4L7|A0A7I2V4L7_HUMAN,tr|E5RHG7|E5RHG7_HUMAN,tr|B1ANR1|B1ANR1_HUMAN,tr|H0YAR2|H0YAR2_HUMAN,tr|E7ERJ7|E7ERJ7_HUMAN,tr|E5RJB9|E5RJB9_HUMAN,tr|A0A7I2YQ88|A0A7I2YQ88_HUMAN,tr|E5RH24|E5RH24_HUMAN,tr|H0YBN4|H0YBN4_HUMAN,tr|E5RGH3|E5RGH3_HUMAN,tr|A0A087WTT1|A0A087WTT1_HUMAN,tr|A0A7I2YQ90|A0A7I2YQ90_HUMAN,tr|E7EQV3|E7EQV3_HUMAN" 17 2104.0241 2.76 68386 17062 3 2104.02586 702.3486 Polyadenylate-binding protein 4 OS=Homo sapiens OX=9606 GN=PABPC4 PE=1 SV=1 6.07 2940.6 - 854548 - - - 0.8403 - 3.772 0.542 - 559.3 1 2 0 0.0018 18 0 0 0 5.56E+06 2.01E+06 - - - 7.8881 0.9999 221125_WJC_METTL3_EV_vs_WT_F05.17063.17063.3 0.00768 Oct-40 K.GKPLALVEEIR.N "sp|Q9BSD7|NTPCR_HUMAN,tr|Q5TDF0|Q5TDF0_HUMAN" 2 1223.7238 1.22 68387 17063 3 1223.72586 408.9152 Cancer-related nucleoside-triphosphatase OS=Homo sapiens OX=9606 GN=NTPCR PE=1 SV=1 6.14 2940.7 - 550349 - - - 1.7063 - 2.251 0.418 - 197.1 1 2 0 0.0021 11 0 0 0 5.64E+06 4.62E+06 - - - 5.5047 0.9994 221125_WJC_METTL3_EV_vs_WT_F05.17064.17064.2 7.27E-06 13/26 R.AEQWNVNYVETSAK[136.11].T "sp|P11233|RALA_HUMAN,tr|H7C3P7|H7C3P7_HUMAN" 2 1645.7828 1.76 68388 17064 2 1645.78227 823.8987 Ras-related protein Ral-A OS=Homo sapiens OX=9606 GN=RALA PE=1 SV=1 4.53 2940.9 - 509115 - - - -0.2917 - 2.194 0.24 - 401.5 1 2 0 -0.0005 14 0 0 0 1.28E+07 7.27E+06 - - - 2.7852 0.9974 221125_WJC_METTL3_EV_vs_WT_F05.17066.17066.4 0.00722 10/102 K.IIEK[136.11]DVMEGVTVDDHMMK[136.11].V "sp|Q5BKZ1|ZN326_HUMAN,tr|A0A0A0MRN4|A0A0A0MRN4_HUMAN" 2 2105.0178 0.6 68390 17066 4 2105.017636 527.2617 DBIRD complex subunit ZNF326 OS=Homo sapiens OX=9606 GN=ZNF326 PE=1 SV=2 4.43 2941.1 - 441028 - - - -0.0703 - 2.003 0.318 - 62.2 1 2 1 -0.0001 18 0 0 0 1.27E+06 2.11E+06 - - - 2.2318 0.9997 221125_WJC_METTL3_EV_vs_WT_F05.17067.17067.3 0.000595 13/48 K.EVHNLNQLLYSQR[166.11].R "sp|Q53EZ4|CEP55_HUMAN,tr|H0Y432|H0Y432_HUMAN" 2 1622.8404 1.19 68391 17067 3 1622.843837 541.9541 Centrosomal protein of 55 kDa OS=Homo sapiens OX=9606 GN=CEP55 PE=1 SV=3 6.85 2941.2 - 413895 - - - 2.1031 - 2.137 0.379 - 213.4 1 2 0 0.0034 13 0 0 0 4.78E+06 4.01E+06 - - - 4.8235 0.9998 221125_WJC_METTL3_EV_vs_WT_F05.17068.17068.3 3.45E-06 Oct-40 R.SKTDLDC[160.03]IFGK.R "sp|Q96BK5|PINX1_HUMAN,tr|E5RGR1|E5RGR1_HUMAN" 2 1282.6227 0.84 68392 17068 3 1282.623081 428.5482 PIN2\TERF1-interacting telomerase inhibitor 1 OS=Homo sapiens OX=9606 GN=PINX1 PE=1 SV=2 5.68 2941.4 - 338271 - - - 0.2674 - 2.041 0.476 - 151.8 1 2 1 0.0003 11 0 0 0 2.04E+06 2.43E+06 - - - 5.8736 0.9999 221125_WJC_METTL3_EV_vs_WT_F05.17069.17069.3 2.69E-05 14/80 K.VGTGEPC[160.03]C[160.03]DWVGDEGAGHFVK.M "sp|P52209|6PGD_HUMAN,tr|K7EPF6|K7EPF6_HUMAN,tr|K7EM49|K7EM49_HUMAN" 3 2275.9627 1.44 68393 17069 3 2275.97007 759.6615 "6-phosphogluconate dehydrogenase, decarboxylating OS=Homo sapiens OX=9606 GN=PGD PE=1 SV=3" 4.31 2941.5 - 337728 - - - 3.2588 - 1.816 0.604 - 151.9 1 2 0 0.0074 21 0 0 0 2.57E+06 1.78E+06 - - - 6.7024 0.9999 221125_WJC_METTL3_EV_vs_WT_F05.17070.17070.3 0.000245 Sep-80 K.VGTGEPC[160.03]C[160.03]DWVGDEGAGHFVK[136.11].M "sp|P52209|6PGD_HUMAN,tr|K7EPF6|K7EPF6_HUMAN,tr|K7EM49|K7EM49_HUMAN" 3 2283.9769 1.44 68394 17070 3 2283.979685 762.3329 "6-phosphogluconate dehydrogenase, decarboxylating OS=Homo sapiens OX=9606 GN=PGD PE=1 SV=3" 4.31 2941.6 - 335195 - - - 1.2399 - 1.809 0.507 - 32.1 1 2 0 0.0028 21 0 0 0 2.57E+06 1.78E+06 - - - 5.6129 0.9693 221125_WJC_METTL3_EV_vs_WT_F05.17074.17074.4 0.137 Jun-72 K.IEDHLDEAIHVLR[166.11].S "sp|P15923|TFE2_HUMAN,tr|K7ENH8|K7ENH8_HUMAN,tr|X6REB3|X6REB3_HUMAN,tr|A0A0A0MRB7|A0A0A0MRB7_HUMAN" 4 1568.8186 3.12 68398 17074 4 1568.820162 393.2119 Transcription factor E2-alpha OS=Homo sapiens OX=9606 GN=TCF3 PE=1 SV=1 4.72 2942.1 - 117692 - - - 0.9791 - 1.325 0.167 - 35.1 1 2 0 0.0015 13 0 0 0 2.09E+06 6.69E+05 - - - 0.7835 1 221125_WJC_METTL3_EV_vs_WT_F05.17077.17077.3 1.12E-16 27/88 R.GNFGGSFAGSFGGAGGHAPGVAR.K "sp|P52272|HNRPM_HUMAN,tr|M0R2I7|M0R2I7_HUMAN,tr|M0QY96|M0QY96_HUMAN,tr|A0A087X0X3|A0A087X0X3_HUMAN" 4 2033.9456 1.77 68399 17077 3 2033.94977 678.9891 Heterogeneous nuclear ribonucleoprotein M OS=Homo sapiens OX=9606 GN=HNRNPM PE=1 SV=3 9.76 2942.6 - 8.53E+06 - - - 2.0404 - 4.72 0.686 - 766.2 1 2 0 0.0041 23 0 0 0 1.68E+08 9.49E+07 - - - 9.8275 1 221125_WJC_METTL3_EV_vs_WT_F05.17078.17078.3 1.54E-07 17/64 M.PNIVLFSGSSHQDLSQR.V "sp|P11908|PRPS2_HUMAN,tr|A6NMS2|A6NMS2_HUMAN,tr|D3YTJ7|D3YTJ7_HUMAN" 3 1883.949 1.22 68400 17078 3 1883.955505 628.9903 Ribose-phosphate pyrophosphokinase 2 OS=Homo sapiens OX=9606 GN=PRPS2 PE=1 SV=2 7.17 2942.6 - 2.50E+06 - - - 3.4661 - 3.758 0.67 - 343.2 1 2 0 0.0065 17 0 0 0 1.98E+07 1.62E+07 - - - 9.3526 1 221125_WJC_METTL3_EV_vs_WT_F05.17080.17080.3 2.67E-05 18/64 M.PNIVLFSGSSHQDLSQR[166.11].V "sp|P11908|PRPS2_HUMAN,tr|A6NMS2|A6NMS2_HUMAN,tr|D3YTJ7|D3YTJ7_HUMAN" 3 1893.9572 1.22 68402 17080 3 1893.968428 632.3264 Ribose-phosphate pyrophosphokinase 2 OS=Homo sapiens OX=9606 GN=PRPS2 PE=1 SV=2 7.17 2942.7 - 1.81E+06 - - - 5.9046 - 4.051 0.639 - 365.1 1 2 0 0.0112 17 0 0 0 1.99E+07 1.63E+07 - - - 9.1953 1 221125_WJC_METTL3_EV_vs_WT_F05.17083.17083.3 1.91E-06 14/48 R.DC[160.03]QIAHGAAQFLR[166.11].E "sp|P30876|RPB2_HUMAN,tr|C9J4M6|C9J4M6_HUMAN,tr|C9J2Y9|C9J2Y9_HUMAN" 3 1495.723 1.18 68405 17083 3 1495.724399 499.5816 DNA-directed RNA polymerase II subunit RPB2 OS=Homo sapiens OX=9606 GN=POLR2B PE=1 SV=1 6.74 2943.1 - 865229 - - - 0.9681 - 2.598 0.491 - 360.7 1 2 0 0.0014 13 0 0 0 7.26E+06 6.13E+06 - - - 6.6023 0.9998 221125_WJC_METTL3_EV_vs_WT_F05.17086.17086.3 2.42E-05 Dec-48 K.EVHNLNQLLYSQR.R "sp|Q53EZ4|CEP55_HUMAN,tr|H0Y432|H0Y432_HUMAN" 2 1612.8322 1.15 68408 17086 3 1612.83576 538.618 Centrosomal protein of 55 kDa OS=Homo sapiens OX=9606 GN=CEP55 PE=1 SV=3 6.85 2943.5 - 585832 - - - 2.2358 - 2.326 0.424 - 162.5 1 2 0 0.0036 13 0 0 0 4.78E+06 4.15E+06 - - - 5.5549 0.9997 221125_WJC_METTL3_EV_vs_WT_F05.17088.17088.2 1.07E-06 13/26 K.SSSQVPPILQETDK.S "sp|Q86UE4|LYRIC_HUMAN,tr|H0YBJ8|H0YBJ8_HUMAN,tr|E5RJU9|E5RJU9_HUMAN" 3 1527.7781 1.06 68410 17088 2 1527.77957 764.8963 Protein LYRIC OS=Homo sapiens OX=9606 GN=MTDH PE=1 SV=2 4.37 2943.7 - 443761 - - - 0.9929 - 2.282 0.357 - 363.7 1 2 0 0.0015 14 0 0 0 6.14E+06 5.79E+06 - - - 3.7478 0.9997 221125_WJC_METTL3_EV_vs_WT_F05.17089.17089.4 7.89E-05 13/72 K.IEDHLDEAIHVLR.S "sp|P15923|TFE2_HUMAN,tr|K7ENH8|K7ENH8_HUMAN,tr|X6REB3|X6REB3_HUMAN,tr|A0A0A0MRB7|A0A0A0MRB7_HUMAN" 4 1558.8104 2.98 68411 17089 4 1558.811652 390.7099 Transcription factor E2-alpha OS=Homo sapiens OX=9606 GN=TCF3 PE=1 SV=1 4.72 2943.9 - 369204 - - - 0.8314 - 1.99 0.355 - 142.3 1 2 0 0.0013 13 0 0 0 2.22E+06 7.45E+05 - - - 2.5707 1 221125_WJC_METTL3_EV_vs_WT_F05.17102.17102.3 1.94E-11 25/68 K.LLVDVDESTLSPEEQKER.K sp|O75533|SF3B1_HUMAN 1 2086.043 1.84 68422 17102 3 2086.045841 696.3549 Splicing factor 3B subunit 1 OS=Homo sapiens OX=9606 GN=SF3B1 PE=1 SV=3 4.08 2945.4 - 1.15E+06 - - - 1.3648 - 3.289 0.625 - 594.5 1 2 1 0.0028 18 0 0 0 1.35E+07 7.34E+06 - - - 8.472 1 221125_WJC_METTL3_EV_vs_WT_F05.17103.17103.3 8.91E-12 25/80 R.GENLVSMTVEGPPPKDTGIAR.V "sp|P63162|RSMN_HUMAN,sp|P14678|RSMB_HUMAN,tr|J3QLE5|J3QLE5_HUMAN" 3 2167.0943 0.33 68423 17103 3 2167.099542 723.372 Small nuclear ribonucleoprotein-associated protein N OS=Homo sapiens OX=9606 GN=SNRPN PE=1 SV=1 4.68 2945.5 - 1.05E+06 - - - 2.4106 - 4.623 0.652 - 1044.8 1 2 1 0.0052 21 0 0 0 4.62E+07 1.42E+08 - - - 9.4783 0.9999 221125_WJC_METTL3_EV_vs_WT_F05.17104.17104.3 1.41E-07 17/60 K.EPFPTIYVDSQK[136.11]ENER[166.11].W "sp|O43776|SYNC_HUMAN,tr|K7EQ35|K7EQ35_HUMAN,tr|K7EIU7|K7EIU7_HUMAN,tr|K7EJ19|K7EJ19_HUMAN,tr|K7EPK2|K7EPK2_HUMAN" 5 1968.9548 0.26 68424 17104 3 1968.95784 657.3255 "Asparagine--tRNA ligase, cytoplasmic OS=Homo sapiens OX=9606 GN=NARS1 PE=1 SV=1" 4.41 2945.6 - 1.04E+06 - - - 1.5485 - 3.559 0.564 - 531.5 1 2 1 0.003 16 0 0 0 2.35E+06 8.94E+06 - - - 8.0845 0.9999 221125_WJC_METTL3_EV_vs_WT_F05.17106.17106.3 1.26E-07 20/68 K.LLVDVDESTLSPEEQK[136.11]ER[166.11].K sp|O75533|SF3B1_HUMAN 1 2104.0655 1.83 68426 17106 3 2104.068478 702.3624 Splicing factor 3B subunit 1 OS=Homo sapiens OX=9606 GN=SF3B1 PE=1 SV=3 4.08 2945.8 - 833717 - - - 1.4325 - 3.514 0.568 - 410.4 1 2 1 0.003 18 0 0 0 1.30E+07 7.10E+06 - - - 8.0013 0.9999 221125_WJC_METTL3_EV_vs_WT_F05.17107.17107.3 0.00104 15/72 R.VR[166.11]PASTGGLSLLPPPPGGK[136.11].T "sp|Q9NVZ3|NECP2_HUMAN,tr|D6RB24|D6RB24_HUMAN" 2 1818.0482 0.11 68427 17107 3 1818.051834 607.0234 Adaptin ear-binding coat-associated protein 2 OS=Homo sapiens OX=9606 GN=NECAP2 PE=1 SV=1 11 2946 - 583757 - - - 1.9779 - 2.735 0.46 - 225.8 1 2 0 0.0036 19 0 0 0 1.07E+06 9.77E+06 - - - 6.1394 0.9995 221125_WJC_METTL3_EV_vs_WT_F05.17110.17110.3 1.01E-05 Dec-56 K.SLEDALSSDTSGHFR.R "sp|P08133|ANXA6_HUMAN,tr|E5RK69|E5RK69_HUMAN,tr|E7EMC6|E7EMC6_HUMAN" 3 1620.738 1.42 68430 17110 3 1620.741322 541.2533 Annexin A6 OS=Homo sapiens OX=9606 GN=ANXA6 PE=1 SV=3 4.53 2946.4 - 431172 - - - 2.0626 - 2.07 0.357 - 120.6 1 2 0 0.0033 15 0 0 0 5.77E+06 4.05E+06 - - - 4.4177 0.9971 221125_WJC_METTL3_EV_vs_WT_F05.17119.17119.3 0.000189 14/48 N.KLNDLEDALQQAK.E sp|P04264|K2C1_HUMAN 1 1484.7835 124.96 68437 17119 3 1484.78461 495.9351 "Keratin, type II cytoskeletal 1 OS=Homo sapiens OX=9606 GN=KRT1 PE=1 SV=6" 4.56 2947.5 - 1.27E+06 - - - 0.7664 - 3.028 0.453 - 465.8 1 1 0 0.0011 13 0 0 0 1.26E+07 1.01E+05 - - - 6.594 0.9998 221125_WJC_METTL3_EV_vs_WT_F05.17122.17122.2 5.90E-06 22-Dec R.TVIIEQSWGSPK.V "sp|P10809|CH60_HUMAN,tr|C9JL25|C9JL25_HUMAN,tr|A0A7I2V2X6|A0A7I2V2X6_HUMAN,tr|A0A7I2YQK6|A0A7I2YQK6_HUMAN,tr|A0A7I2V599|A0A7I2V599_HUMAN,tr|E7EXB4|E7EXB4_HUMAN,tr|C9JL19|C9JL19_HUMAN,tr|A0A7I2YQ71|A0A7I2YQ71_HUMAN,tr|E7ESH4|E7ESH4_HUMAN,tr|A0A7I2V5M1|A0A7I2V5M1_HUMAN,tr|A0A7I2V5K3|A0A7I2V5K3_HUMAN,tr|A0A7I2V369|A0A7I2V369_HUMAN,tr|C9JCQ4|C9JCQ4_HUMAN" 13 1343.7085 1.28 68440 17122 2 1343.710674 672.8615 "60 kDa heat shock protein, mitochondrial OS=Homo sapiens OX=9606 GN=HSPD1 PE=1 SV=2" 5.66 2947.8 - 971685 - - - 1.606 - 2.626 0.539 - 453 1 2 0 0.0022 12 0 0 0 2.64E+07 2.06E+07 - - - 5.5617 0.9995 221125_WJC_METTL3_EV_vs_WT_F05.17123.17123.3 0.000243 Nov-48 K.KLLDLVQQSC[160.03]NYK.Q "sp|P55769|NH2L1_HUMAN,tr|B1AHD1|B1AHD1_HUMAN,tr|A0A3B3IUA2|A0A3B3IUA2_HUMAN" 3 1607.8341 1.62 68441 17123 3 1607.839617 536.952 NHP2-like protein 1 OS=Homo sapiens OX=9606 GN=SNU13 PE=1 SV=3 8.18 2947.8 - 954347 - - - 3.4139 - 1.991 0.431 - 186.3 1 2 0 0.0055 13 0 0 0 3.48E+07 2.14E+07 - - - 5.2108 0.9991 221125_WJC_METTL3_EV_vs_WT_F05.17126.17126.3 0.633 Nov-56 K.ELAEEEPHLVEQFQK.L "sp|P40855|PEX19_HUMAN,tr|E9PS71|E9PS71_HUMAN,tr|Q5QNY5|Q5QNY5_HUMAN,tr|B7Z8B3|B7Z8B3_HUMAN" 4 1824.8894 0.16 68444 17126 3 1824.893405 609.3037 Peroxisomal biogenesis factor 19 OS=Homo sapiens OX=9606 GN=PEX19 PE=1 SV=1 4.32 2948.2 - 541613 - - - 2.1979 - 1.89 0.338 - 143.5 1 2 0 0.004 15 0 0 0 1.17E+07 7.37E+07 - - - 3.9683 0.9887 221125_WJC_METTL3_EV_vs_WT_F05.17130.17130.2 1.36E-06 24-Aug R.ATC[160.03]NNYTPQFQLR.P sp|Q5T749|KPRP_HUMAN 1 1611.7464 999 68448 17130 2 1611.7476 806.8805 Keratinocyte proline-rich protein OS=Homo sapiens OX=9606 GN=KPRP PE=1 SV=1 8.27 2948.7 - 254173 - - - 0.76 - 1.896 0.504 - 163.1 1 1 0 0.0012 13 0 0 0 2.70E+06 0.00E+00 - - - 4.4051 0.9999 221125_WJC_METTL3_EV_vs_WT_F05.17131.17131.3 4.14E-08 14/64 K.LSDTTEYQPILSSYSHR[166.11].A sp|Q5VT52|RPRD2_HUMAN 1 2005.9621 1.1 68449 17131 3 2005.969996 669.6613 Regulation of nuclear pre-mRNA domain-containing protein 2 OS=Homo sapiens OX=9606 GN=RPRD2 PE=1 SV=1 5.32 2948.8 - 229330 - - - 3.9587 - 2.969 0.568 - 199.6 1 2 0 0.0079 17 0 0 0 1.04E+07 9.52E+06 - - - 7.6196 1 221125_WJC_METTL3_EV_vs_WT_F05.17136.17136.3 3.00E-09 29/92 R.AAPLAAPPPAPAAPPAVAPPAGPR.R sp|Q6SPF0|SAMD1_HUMAN 1 2124.1844 2.83 68452 17136 3 2124.186732 709.0687 Sterile alpha motif domain-containing protein 1 OS=Homo sapiens OX=9606 GN=SAMD1 PE=1 SV=1 9.79 2949.5 - 1.48E+06 - - - 1.1007 - 4.694 0.644 - 709.5 1 2 0 0.0023 24 0 0 0 3.95E+07 1.40E+07 - - - 9.3107 1 221125_WJC_METTL3_EV_vs_WT_F05.17139.17139.3 2.82E-05 18/56 R.EAEDTQVFGDLPRPR.L sp|Q96B36|AKTS1_HUMAN 1 1728.8431 1.34 68455 17139 3 1728.847557 577.2883 Proline-rich AKT1 substrate 1 OS=Homo sapiens OX=9606 GN=AKT1S1 PE=1 SV=1 4.32 2949.8 - 670190 - - - 2.5711 - 3.253 0.55 - 554 1 2 0 0.0044 15 0 0 0 9.02E+07 6.72E+07 - - - 7.7487 1 221125_WJC_METTL3_EV_vs_WT_F05.17140.17140.3 1.03E-10 27/92 R.AAPLAAPPPAPAAPPAVAPPAGPR[166.11].R sp|Q6SPF0|SAMD1_HUMAN 1 2134.1927 3.07 68456 17140 3 2134.191321 712.4048 Sterile alpha motif domain-containing protein 1 OS=Homo sapiens OX=9606 GN=SAMD1 PE=1 SV=1 9.79 2949.9 - 625242 - - - -0.6293 - 4.117 0.609 - 674.8 1 2 0 -0.0013 24 0 0 0 4.28E+07 1.40E+07 - - - 8.6161 1 221125_WJC_METTL3_EV_vs_WT_F05.17141.17141.3 6.49E-05 15/64 K.LSDTTEYQPILSSYSHR.A sp|Q5VT52|RPRD2_HUMAN 1 1995.9538 1.09 68457 17141 3 1995.951194 666.3252 Regulation of nuclear pre-mRNA domain-containing protein 2 OS=Homo sapiens OX=9606 GN=RPRD2 PE=1 SV=1 5.32 2950.1 - 573328 - - - -1.2981 - 2.653 0.464 - 179 1 2 0 -0.0026 17 0 0 0 1.04E+07 9.52E+06 - - - 6.1773 0.9999 221125_WJC_METTL3_EV_vs_WT_F05.17142.17142.3 9.04E-06 14/56 R.NQTPLPLIKPYSGPR.L "sp|Q16594|TAF9_HUMAN,tr|D6RIE8|D6RIE8_HUMAN,tr|D6RIV9|D6RIV9_HUMAN,tr|D6RIY1|D6RIY1_HUMAN,tr|D6RGK3|D6RGK3_HUMAN" 5 1679.9359 1.77 68458 17142 3 1679.939837 560.9859 Transcription initiation factor TFIID subunit 9 OS=Homo sapiens OX=9606 GN=TAF9 PE=1 SV=1 9.99 2950.2 - 364983 - - - 2.3489 - 2.644 0.461 - 255.7 1 2 0 0.0039 15 0 0 0 5.46E+06 3.08E+06 - - - 6.2157 1 221125_WJC_METTL3_EV_vs_WT_F05.17147.17147.2 9.95E-06 13/30 R.EAVC[160.03]IVLSDDTC[160.03]SDEK[136.11].L "sp|P55072|TERA_HUMAN,tr|A0A7P0Z4C6|A0A7P0Z4C6_HUMAN,tr|A0A7I2V2Y2|A0A7I2V2Y2_HUMAN,tr|A0A7P0T8Q5|A0A7P0T8Q5_HUMAN,tr|C9JUP7|C9JUP7_HUMAN,tr|A0A7P0T971|A0A7P0T971_HUMAN,tr|A0A7P0TAW3|A0A7P0TAW3_HUMAN,tr|A0A7P0Z4D1|A0A7P0Z4D1_HUMAN,tr|A0A7I2V540|A0A7I2V540_HUMAN,tr|A0A7P0T8A3|A0A7P0T8A3_HUMAN,tr|A0A7P0TAQ1|A0A7P0TAQ1_HUMAN,tr|A0A7I2V5G8|A0A7I2V5G8_HUMAN,tr|A0A7P0T946|A0A7P0T946_HUMAN,tr|A0A7P0TBK7|A0A7P0TBK7_HUMAN" 14 1847.8008 0.81 68463 17147 2 1847.802697 924.9077 Transitional endoplasmic reticulum ATPase OS=Homo sapiens OX=9606 GN=VCP PE=1 SV=4 3.77 2950.8 - 179094 - - - 1.0023 - 2.829 0.655 - 490.4 1 2 0 0.0019 16 0 0 0 2.21E+06 2.74E+06 - - - 6.4349 1 221125_WJC_METTL3_EV_vs_WT_F05.17150.17150.3 8.98E-12 20/76 R.AIGDVFQKPYVSGEADAASR.A "sp|P49593|PPM1F_HUMAN,tr|B5MCT7|B5MCT7_HUMAN" 2 2080.0225 1.92 68464 17150 3 2080.025475 694.3481 Protein phosphatase 1F OS=Homo sapiens OX=9606 GN=PPM1F PE=1 SV=3 4.56 2951.3 - 1.30E+06 - - - 1.4144 - 3.432 0.615 - 441.9 1 2 0 0.0029 20 0 0 0 1.58E+07 8.25E+06 - - - 8.3875 1 221125_WJC_METTL3_EV_vs_WT_F05.17152.17152.3 1.24E-09 26/80 R.GENLVSMTVEGPPPK[136.11]DTGIAR[166.11].V "sp|P63162|RSMN_HUMAN,sp|P14678|RSMB_HUMAN,tr|J3QLE5|J3QLE5_HUMAN" 3 2185.1168 0.14 68466 17152 3 2185.118712 729.3795 Small nuclear ribonucleoprotein-associated protein N OS=Homo sapiens OX=9606 GN=SNRPN PE=1 SV=1 4.68 2951.5 - 2.07E+06 - - - 0.8805 - 4.706 0.631 - 1013.2 1 2 1 0.0019 21 0 0 0 1.53E+07 1.09E+08 - - - 9.2878 0.9999 221125_WJC_METTL3_EV_vs_WT_F05.17157.17157.4 0.000731 19/96 K.IFASIAPSIYGHEDIK[136.11]R[166.11].G "sp|P49736|MCM2_HUMAN,tr|H0Y8E6|H0Y8E6_HUMAN" 2 1934.0381 1.1 68471 17157 4 1934.041205 484.5168 DNA replication licensing factor MCM2 OS=Homo sapiens OX=9606 GN=MCM2 PE=1 SV=4 6.75 2952 - 476792 - - - 1.622 - 3.178 0.419 - 430.3 1 2 0 0.0031 17 0 0 0 3.99E+06 3.61E+06 - - - 3.2736 1 221125_WJC_METTL3_EV_vs_WT_F05.17158.17158.4 3.47E-08 19/96 K.IFASIAPSIYGHEDIKR.G "sp|P49736|MCM2_HUMAN,tr|H0Y8E6|H0Y8E6_HUMAN" 2 1916.0156 1.1 68472 17158 4 1916.018426 480.0112 DNA replication licensing factor MCM2 OS=Homo sapiens OX=9606 GN=MCM2 PE=1 SV=4 6.75 2952.2 - 470820 - - - 1.476 - 3.81 0.548 - 520.2 1 2 0 0.0028 17 0 0 0 3.99E+06 3.61E+06 - - - 4.4594 0.999 221125_WJC_METTL3_EV_vs_WT_F05.17160.17160.3 5.02E-07 13/52 K.NRVEINDVEPEVFK.E sp|O43791|SPOP_HUMAN 1 1686.8577 3.46 68474 17160 3 1686.851897 563.2932 Speckle-type POZ protein OS=Homo sapiens OX=9606 GN=SPOP PE=1 SV=1 4.41 2952.4 - 281810 - - - -3.4401 - 2.155 0.493 - 195.2 1 2 1 -0.0058 14 0 0 0 4.01E+06 1.16E+06 - - - 6.0753 0.9809 221125_WJC_METTL3_EV_vs_WT_F05.17161.17161.3 3.89E-05 Sep-44 R.K[136.11]AHEILPNLVC[160.03]C[160.03].S "sp|P50990|TCPQ_HUMAN,tr|H7C4C8|H7C4C8_HUMAN" 2 1460.7359 0.44 68475 17161 3 1460.73806 487.9193 T-complex protein 1 subunit theta OS=Homo sapiens OX=9606 GN=CCT8 PE=1 SV=4 6.73 2952.6 - 206278 - - - 1.4506 - 1.873 0.417 - 103.7 1 1 0 0.0021 12 0 0 0 1.31E+06 2.95E+06 - - - 4.928 0.9999 221125_WJC_METTL3_EV_vs_WT_F05.17171.17171.4 4.71E-06 15/96 R.FDSYPMVLGAQHFHSGK.H "sp|P19474|RO52_HUMAN,tr|H0YDP8|H0YDP8_HUMAN" 2 1919.8989 1.46 68483 17171 4 1919.904261 480.982 E3 ubiquitin-protein ligase TRIM21 OS=Homo sapiens OX=9606 GN=TRIM21 PE=1 SV=1 6.92 2953.9 - 477575 - - - 2.8168 - 3.111 0.488 - 186.9 1 2 0 0.0054 17 0 0 0 6.59E+06 4.50E+06 - - - 3.8661 0.9999 221125_WJC_METTL3_EV_vs_WT_F05.17173.17173.4 1.59E-05 15/96 R.FDSYPMVLGAQHFHSGK[136.11].H "sp|P19474|RO52_HUMAN,tr|H0YDP8|H0YDP8_HUMAN" 2 1927.9131 1.49 68485 17173 4 1927.913783 482.9855 E3 ubiquitin-protein ligase TRIM21 OS=Homo sapiens OX=9606 GN=TRIM21 PE=1 SV=1 6.92 2954.1 - 328983 - - - 0.3786 - 2.81 0.411 - 182.7 1 2 0 0.0007 17 0 0 0 6.59E+06 4.43E+06 - - - 3.1619 0.9998 221125_WJC_METTL3_EV_vs_WT_F05.17175.17175.2 3.61E-05 24-Nov K.K[136.11]LLDLVQQSC[160.03]NYK[136.11].Q "sp|P55769|NH2L1_HUMAN,tr|B1AHD1|B1AHD1_HUMAN,tr|A0A3B3IUA2|A0A3B3IUA2_HUMAN" 3 1623.8625 1.18 68487 17175 2 1623.864124 812.9385 NHP2-like protein 1 OS=Homo sapiens OX=9606 GN=SNU13 PE=1 SV=3 8.18 2954.4 - 248945 - - - 0.9828 - 2.256 0.506 - 326.5 1 2 0 0.0016 13 0 0 0 2.21E+06 1.87E+06 - - - 4.8659 1 221125_WJC_METTL3_EV_vs_WT_F05.17179.17179.3 8.76E-12 17/64 R.TYADYESVNEC[160.03]MEGVC[160.03]K.M "sp|P84090|ERH_HUMAN,tr|G3V279|G3V279_HUMAN" 2 2053.8067 2.09 68489 17179 3 2053.808467 685.6095 Enhancer of rudimentary homolog OS=Homo sapiens OX=9606 GN=ERH PE=1 SV=1 4 2954.9 - 3.56E+06 - - - 0.8462 - 3.047 0.726 - 369.6 1 2 0 0.0017 17 0 0 0 6.50E+07 3.11E+07 - - - 9.4484 0.9969 221125_WJC_METTL3_EV_vs_WT_F05.17186.17186.4 0.0111 Oct-90 K.TLEHLQLSHDQLLEVK[136.11].R "sp|P52789|HXK2_HUMAN,tr|E9PB90|E9PB90_HUMAN" 2 1910.0353 0.84 68496 17186 4 1910.035465 478.5161 Hexokinase-2 OS=Homo sapiens OX=9606 GN=HK2 PE=1 SV=2 5.26 2955.8 - 243582 - - - 0.0984 - 1.524 0.256 - 42.8 1 2 0 0.0002 16 0 0 0 3.01E+06 3.57E+06 - - - 1.6026 0.9998 221125_WJC_METTL3_EV_vs_WT_F05.17188.17188.4 6.61E-06 Dec-78 K.YKDDPVDLRLDIER.R "sp|Q9Y2W1|TR150_HUMAN,tr|A0A3B3ITZ9|A0A3B3ITZ9_HUMAN" 2 1745.8948 2.36 68498 17188 4 1745.897729 437.481 Thyroid hormone receptor-associated protein 3 OS=Homo sapiens OX=9606 GN=THRAP3 PE=1 SV=2 4.36 2956.1 - 160101 - - - 1.6696 - 2.411 0.511 - 130.1 1 2 2 0.0029 14 0 0 0 5.89E+06 2.50E+06 - - - 3.9932 0.9998 221125_WJC_METTL3_EV_vs_WT_F05.17190.17190.2 0.000216 28-Jul K.QYDSVEC[160.03]PFC[160.03]DEVSK[136.11].Y "sp|P50750|CDK9_HUMAN,tr|X6RE90|X6RE90_HUMAN" 2 1869.7641 0.24 68500 17190 2 1869.764086 935.8893 Cyclin-dependent kinase 9 OS=Homo sapiens OX=9606 GN=CDK9 PE=1 SV=3 3.92 2956.4 - 113606 - - - 0.0107 - 1.555 0.504 - 134.9 1 2 0 0 15 0 0 0 3.21E+05 1.34E+06 - - - 3.8489 1 221125_WJC_METTL3_EV_vs_WT_F05.17197.17197.3 5.15E-09 17/56 R.EAEDTQVFGDLPR[166.11]PR[166.11].L sp|Q96B36|AKTS1_HUMAN 1 1748.8597 1.54 68505 17197 3 1748.859845 583.9605 Proline-rich AKT1 substrate 1 OS=Homo sapiens OX=9606 GN=AKT1S1 PE=1 SV=1 4.32 2957.3 - 1.34E+06 - - - 0.1104 - 3.315 0.625 - 459.5 1 2 0 0.0002 15 0 0 0 7.98E+07 5.17E+07 - - - 8.6353 1 221125_WJC_METTL3_EV_vs_WT_F05.17198.17198.3 5.05E-07 Oct-76 K.TLEPVKPPTVPNDYMTSPAR.L "sp|Q8IZP0|ABI1_HUMAN,tr|A0A0A0MRT6|A0A0A0MRT6_HUMAN,tr|B6VEX4|B6VEX4_HUMAN" 3 2212.1198 1.75 68506 17198 3 2212.122298 738.3805 Abl interactor 1 OS=Homo sapiens OX=9606 GN=ABI1 PE=1 SV=4 5.73 2957.4 - 316680 - - - 1.127 - 2.429 0.595 - 75.7 1 2 0 0.0025 20 0 0 0 3.50E+06 2.00E+06 - - - 7.326 0.9999 221125_WJC_METTL3_EV_vs_WT_F05.17200.17200.3 6.77E-05 13/48 R.HC[160.03]QLLETPESWAK.E "sp|P52948|NUP98_HUMAN,tr|H7C3P6|H7C3P6_HUMAN" 2 1597.7559 2.3 68508 17200 3 1597.755691 533.5926 Nuclear pore complex protein Nup98-Nup96 OS=Homo sapiens OX=9606 GN=NUP98 PE=1 SV=4 5.4 2957.7 - 260123 - - - -0.117 - 2.062 0.484 - 225.9 1 2 0 -0.0002 13 0 0 0 3.79E+06 1.65E+06 - - - 5.8982 0.9998 221125_WJC_METTL3_EV_vs_WT_F05.17201.17201.2 1.64E-07 24-Oct K.FC[160.03]ADSDGFSQELR.N "sp|P52732|KIF11_HUMAN,tr|A0A7I2V3A9|A0A7I2V3A9_HUMAN" 2 1530.6409 1.79 68509 17201 2 1530.643236 766.3277 Kinesin-like protein KIF11 OS=Homo sapiens OX=9606 GN=KIF11 PE=1 SV=2 4.03 2957.8 - 207836 - - - 1.5216 - 2.092 0.583 - 331.1 1 2 0 0.0023 13 0 0 0 2.81E+06 1.57E+06 - - - 5.2407 0.9999 221125_WJC_METTL3_EV_vs_WT_F05.17205.17205.2 2.78E-07 28-Sep K.YQEYTNELQETLPQK.M "sp|Q9UHD2|TBK1_HUMAN,tr|A0A7I2V646|A0A7I2V646_HUMAN,tr|A0A494C045|A0A494C045_HUMAN,tr|A0A7I2V4W4|A0A7I2V4W4_HUMAN,tr|A0A494C148|A0A494C148_HUMAN,tr|A0A494C0X2|A0A494C0X2_HUMAN,tr|A0A494C167|A0A494C167_HUMAN,tr|A0A7I2V2F4|A0A7I2V2F4_HUMAN,tr|A0A7I2V643|A0A7I2V643_HUMAN" 9 1882.8949 8.37 68513 17205 2 1882.894315 942.4547 Serine\threonine-protein kinase TBK1 OS=Homo sapiens OX=9606 GN=TBK1 PE=1 SV=1 4.25 2958.3 - 128070 - - - -0.2964 - 1.981 0.565 - 169.4 1 2 0 -0.0006 15 0 0 0 7.00E+06 8.36E+05 - - - 4.8946 1 221125_WJC_METTL3_EV_vs_WT_F05.17208.17208.2 2.60E-12 20/32 R.TYADYESVNEC[160.03]MEGVC[160.03]K.M "sp|P84090|ERH_HUMAN,tr|G3V279|G3V279_HUMAN" 2 2053.8067 2.14 68514 17208 2 2053.806869 1027.9106 Enhancer of rudimentary homolog OS=Homo sapiens OX=9606 GN=ERH PE=1 SV=1 4 2958.7 - 5.78E+06 - - - 0.0682 - 3.868 0.756 - 1147.8 1 2 0 0.0001 17 0 0 0 7.17E+07 3.35E+07 - - - 7.9505 0.9992 221125_WJC_METTL3_EV_vs_WT_F05.17211.17211.4 0.00648 Dec-96 K.FDPYEHEALFHTPVEGK.E sp|Q9HAV7|GRPE1_HUMAN 1 2014.9425 1.18 68517 17211 4 2014.943097 504.7429 "GrpE protein homolog 1, mitochondrial OS=Homo sapiens OX=9606 GN=GRPEL1 PE=1 SV=2" 4.8 2959 - 663465 - - - 0.3003 - 1.839 0.311 - 91 1 2 0 0.0006 17 0 0 0 1.21E+07 1.03E+07 - - - 2.1443 0.9999 221125_WJC_METTL3_EV_vs_WT_F05.17215.17215.3 2.90E-06 14/60 K.ISQDVDK[136.11]EDEFGYSWK[136.11].N "sp|O75970|MPDZ_HUMAN,tr|B7ZB24|B7ZB24_HUMAN,tr|F8WDQ8|F8WDQ8_HUMAN,tr|H0YGQ3|H0YGQ3_HUMAN,tr|F5H1U9|F5H1U9_HUMAN,tr|H0YH70|H0YH70_HUMAN" 6 1960.9025 2.7 68521 17215 3 1960.89872 654.6415 Multiple PDZ domain protein OS=Homo sapiens OX=9606 GN=MPDZ PE=1 SV=2 4.11 2959.5 - 327149 - - - -1.9471 - 2.968 0.563 - 249.3 1 2 1 -0.0038 16 0 0 0 6.95E+06 2.57E+06 - - - 7.6072 1 221125_WJC_METTL3_EV_vs_WT_F05.17217.17217.2 8.45E-07 30-Nov K.DVNDWVGPPNDNGVTK.E "sp|P0DTE8|AMY1C_HUMAN,sp|P0DTE7|AMY1B_HUMAN,sp|P0DUB6|AMY1A_HUMAN" 3 1725.7958 999 68523 17217 2 1725.798381 863.9052 Alpha-amylase 1C OS=Homo sapiens OX=9606 GN=AMY1C PE=1 SV=1 3.93 2959.8 - 288322 - - - 1.4793 - 2.493 0.65 - 303.8 1 2 0 0.0026 16 0 0 0 4.86E+06 0.00E+00 - - - 6.0869 0.9999 221125_WJC_METTL3_EV_vs_WT_F05.17219.17219.3 0.000116 Dec-88 R.SLFSPQNTLAAPTGHPPTSGVEK[136.11].V sp|Q5VT52|RPRD2_HUMAN 1 2343.195 2.28 68525 17219 3 2343.198819 782.0723 Regulation of nuclear pre-mRNA domain-containing protein 2 OS=Homo sapiens OX=9606 GN=RPRD2 PE=1 SV=1 6.47 2960.1 - 215791 - - - 1.6192 - 2.346 0.442 - 110.2 1 2 0 0.0038 23 0 0 0 8.24E+06 3.62E+06 - - - 5.4672 0.9999 221125_WJC_METTL3_EV_vs_WT_F05.17228.17228.3 1.22E-05 Nov-64 K.FDPYEHEALFHTPVEGK.E sp|Q9HAV7|GRPE1_HUMAN 1 2014.9425 0.63 68533 17228 3 2014.942147 672.6548 "GrpE protein homolog 1, mitochondrial OS=Homo sapiens OX=9606 GN=GRPEL1 PE=1 SV=2" 4.8 2961 - 385594 - - - -0.1712 - 2.199 0.462 - 113.5 1 2 0 -0.0003 17 0 0 0 4.84E+06 7.70E+06 - - - 5.6815 0.999 221125_WJC_METTL3_EV_vs_WT_F05.17229.17229.3 0.000549 Sep-64 K.GSPEDK[136.11]DSEIELLTAGK[136.11].K sp|Q9NU22|MDN1_HUMAN 1 1803.9073 0.71 68534 17229 3 1803.907571 602.3097 Midasin OS=Homo sapiens OX=9606 GN=MDN1 PE=1 SV=2 4.18 2961.1 - 373295 - - - 0.1563 - 1.898 0.39 - 134.7 1 2 1 0.0003 17 0 0 0 2.58E+06 3.62E+06 - - - 4.5069 0.9986 221125_WJC_METTL3_EV_vs_WT_F05.17230.17230.3 0.00989 Sep-44 K.DGFLHETLLDRR.A sp|Q14331|FRG1_HUMAN 1 1470.7579 0.66 68535 17230 3 1470.758158 491.2599 Protein FRG1 OS=Homo sapiens OX=9606 GN=FRG1 PE=1 SV=1 5.38 2961.2 - 257921 - - - 0.1577 - 1.568 0.294 - 89.6 1 2 0 0.0002 12 0 0 0 4.36E+06 6.57E+06 - - - 3.0645 0.994 221125_WJC_METTL3_EV_vs_WT_F05.17231.17231.2 0.00446 Jul-36 R.LGLGGNAPVSIPQQSQSVK[136.11].Q "sp|Q9H2P0|ADNP_HUMAN,tr|A0A2R8Y6X0|A0A2R8Y6X0_HUMAN,tr|A0A669KBJ7|A0A669KBJ7_HUMAN" 3 1887.0305 1.02 68536 17231 2 1887.026918 944.5225 Activity-dependent neuroprotector homeobox protein OS=Homo sapiens OX=9606 GN=ADNP PE=1 SV=1 8.75 2961.4 - 244471 - - - -1.912 - 1.408 0.218 - 63.2 1 2 0 -0.0036 19 0 0 0 4.55E+06 4.45E+06 - - - 1.4913 0.9999 221125_WJC_METTL3_EV_vs_WT_F05.17233.17233.2 2.45E-06 Nov-36 R.LGLGGNAPVSIPQQSQSVK.Q "sp|Q9H2P0|ADNP_HUMAN,tr|A0A2R8Y6X0|A0A2R8Y6X0_HUMAN,tr|A0A669KBJ7|A0A669KBJ7_HUMAN" 3 1879.0163 1.02 68538 17233 2 1879.015745 940.5154 Activity-dependent neuroprotector homeobox protein OS=Homo sapiens OX=9606 GN=ADNP PE=1 SV=1 8.75 2961.6 - 228062 - - - -0.3092 - 2.316 0.57 - 159.7 1 2 0 -0.0006 19 0 0 0 4.55E+06 4.45E+06 - - - 5.3156 1 221125_WJC_METTL3_EV_vs_WT_F05.17234.17234.2 1.07E-07 14/34 R.GHVTQDAPIPGSPLYTIK.A sp|Q15029|U5S1_HUMAN 1 1892.9996 2.82 68539 17234 2 1893.001627 947.5071 116 kDa U5 small nuclear ribonucleoprotein component OS=Homo sapiens OX=9606 GN=EFTUD2 PE=1 SV=1 6.74 2961.8 - 129318 - - - 1.0639 - 2.752 0.672 - 414.9 1 2 0 0.002 18 0 0 0 3.40E+06 1.20E+06 - - - 6.4926 1 221125_WJC_METTL3_EV_vs_WT_F05.17238.17238.3 1.43E-10 15/68 R.GHVTQDAPIPGSPLYTIK[136.11].A sp|Q15029|U5S1_HUMAN 1 1901.0138 2.2 68541 17238 3 1901.014718 634.6785 116 kDa U5 small nuclear ribonucleoprotein component OS=Homo sapiens OX=9606 GN=EFTUD2 PE=1 SV=1 6.74 2962.2 - 4.19E+06 - - - 0.4761 - 2.957 0.665 - 186.9 1 2 0 0.0009 18 0 0 0 1.20E+08 5.46E+07 - - - 8.6535 1 221125_WJC_METTL3_EV_vs_WT_F05.17239.17239.3 1.35E-06 17/60 R.NYGILADATEQVGQHK.D "sp|Q9BZZ5|API5_HUMAN,tr|E9PQK6|E9PQK6_HUMAN,tr|G3V1C3|G3V1C3_HUMAN" 3 1742.8588 0.85 68542 17239 3 1742.860887 581.9602 Apoptosis inhibitor 5 OS=Homo sapiens OX=9606 GN=API5 PE=1 SV=3 5.32 2962.3 - 2.35E+06 - - - 1.2187 - 3.295 0.429 - 310.1 1 2 0 0.0021 16 0 0 0 2.18E+07 2.55E+07 - - - 6.3819 0.9999 221125_WJC_METTL3_EV_vs_WT_F05.17240.17240.3 0.00292 14/52 K.NELLPSHPLELSEK.N sp|Q9Y244|POMP_HUMAN 1 1604.841 3.14 68543 17240 3 1604.840429 535.9543 Proteasome maturation protein OS=Homo sapiens OX=9606 GN=POMP PE=1 SV=1 4.75 2962.4 - 683744 - - - -0.3477 - 2.703 0.407 - 240.8 1 2 0 -0.0006 14 0 0 0 1.02E+07 3.24E+06 - - - 5.72 0.9999 221125_WJC_METTL3_EV_vs_WT_F05.17245.17245.3 0.00305 Nov-48 R.NILDFPQHVSPSK.D "sp|P52888|THOP1_HUMAN,tr|K7EKB6|K7EKB6_HUMAN" 2 1480.7674 0.25 68548 17245 3 1480.767562 494.5964 Thimet oligopeptidase OS=Homo sapiens OX=9606 GN=THOP1 PE=1 SV=2 6.74 2963 - 201205 - - - 0.0905 - 1.955 0.412 - 141.6 1 2 0 0.0001 13 0 0 0 2.88E+06 1.17E+07 - - - 4.951 0.9999 221125_WJC_METTL3_EV_vs_WT_F05.17246.17246.3 0.000274 Sep-40 K.AETDHLFDLSR.R "sp|Q9NPF5|DMAP1_HUMAN,tr|Q5TG39|Q5TG39_HUMAN,tr|Q5TG38|Q5TG38_HUMAN,tr|Q5TG40|Q5TG40_HUMAN,tr|Q5TG37|Q5TG37_HUMAN" 5 1302.6204 1.16 68549 17246 3 1302.622052 435.2141 DNA methyltransferase 1-associated protein 1 OS=Homo sapiens OX=9606 GN=DMAP1 PE=1 SV=1 4.54 2963.1 - 193296 - - - 1.2452 - 2.012 0.448 - 153.8 1 2 0 0.0016 11 0 0 0 3.38E+06 2.92E+06 - - - 5.5204 0.9997 221125_WJC_METTL3_EV_vs_WT_F05.17253.17253.3 0.000751 Dec-56 K.GFK[136.11]FDETEQALANER[166.11].K "sp|Q7L014|DDX46_HUMAN,tr|A0A0C4DG89|A0A0C4DG89_HUMAN" 2 1771.8496 1.91 68554 17253 3 1771.849702 591.6238 Probable ATP-dependent RNA helicase DDX46 OS=Homo sapiens OX=9606 GN=DDX46 PE=1 SV=2 4.41 2964 - 545818 - - - 0.0587 - 2.299 0.434 - 182.1 1 2 1 0.0001 15 0 0 0 9.87E+06 5.16E+06 - - - 5.5509 1 221125_WJC_METTL3_EV_vs_WT_F05.17257.17257.2 8.85E-11 Sep-32 R.TYADYESVNEC[160.03]MEGVC[160.03]K[136.11].M "sp|P84090|ERH_HUMAN,tr|G3V279|G3V279_HUMAN" 2 2061.8209 2.14 68558 17257 2 2061.818634 1031.9177 Enhancer of rudimentary homolog OS=Homo sapiens OX=9606 GN=ERH PE=1 SV=1 4 2964.5 - 349934 - - - -1.1131 - 2.252 0.77 - 162.6 1 2 0 -0.0023 17 0 0 0 7.30E+07 3.41E+07 - - - 6.7234 1 221125_WJC_METTL3_EV_vs_WT_F05.17258.17258.2 1.59E-08 28-Dec K.QDLPNAMNAAEITDK.L "sp|P84077|ARF1_HUMAN,sp|P61204|ARF3_HUMAN,tr|H0YGG7|H0YGG7_HUMAN" 3 1629.7668 1.24 68559 17258 2 1629.762974 815.8907 ADP-ribosylation factor 1 OS=Homo sapiens OX=9606 GN=ARF1 PE=1 SV=2 4.03 2964.7 - 282416 - - - -2.3697 - 2.736 0.642 - 426.1 1 2 0 -0.0039 15 0 0 0 3.46E+06 2.80E+06 - - - 6.2561 0.9876 221125_WJC_METTL3_EV_vs_WT_F05.17262.17262.3 0.265 Jul-40 K.HFSVEGQLEFR[166.11].A "sp|P08238|HS90B_HUMAN,sp|Q58FF7|H90B3_HUMAN,sp|Q58FG1|HS904_HUMAN,sp|P07900|HS90A_HUMAN,sp|Q14568|HS902_HUMAN" 5 1357.6654 0.88 68563 17262 3 1357.665747 453.5624 Heat shock protein HSP 90-beta OS=Homo sapiens OX=9606 GN=HSP90AB1 PE=1 SV=4 5.4 2965.2 - 143477 - - - 0.2416 - 1.596 0.162 - 108.7 1 2 0 0.0003 11 0 0 0 1.25E+06 1.41E+06 - - - 1.6741 1 221125_WJC_METTL3_EV_vs_WT_F05.17266.17266.3 1.10E-11 18/68 R.GHVTQDAPIPGSPLYTIK.A sp|Q15029|U5S1_HUMAN 1 1892.9996 2.22 68565 17266 3 1893.000026 632.0071 116 kDa U5 small nuclear ribonucleoprotein component OS=Homo sapiens OX=9606 GN=EFTUD2 PE=1 SV=1 6.74 2965.7 - 1.03E+07 - - - 0.2182 - 3.351 0.704 - 418 1 2 0 0.0004 18 0 0 0 1.21E+08 5.46E+07 - - - 9.4 0.9998 221125_WJC_METTL3_EV_vs_WT_F05.17267.17267.3 0.000252 Nov-52 R.AITHLNNNFMFGQK.L "sp|P14866|HNRPL_HUMAN,tr|M0QYT0|M0QYT0_HUMAN,tr|A0A3B3ITJ4|A0A3B3ITJ4_HUMAN,tr|M0QXS5|M0QXS5_HUMAN" 4 1633.8035 0.78 68566 17267 3 1633.804877 545.6084 Heterogeneous nuclear ribonucleoprotein L OS=Homo sapiens OX=9606 GN=HNRNPL PE=1 SV=2 8.8 2965.9 - 769115 - - - 0.8453 - 2.25 0.366 - 125.4 1 2 0 0.0014 14 0 0 0 7.80E+06 9.99E+06 - - - 4.7752 1 221125_WJC_METTL3_EV_vs_WT_F05.17268.17268.2 1.40E-12 24/28 K.VIEHIMEDLDTNADK.Q sp|P06702|S10A9_HUMAN 1 1741.8193 999 68567 17268 2 1741.819509 871.9169 Protein S100-A9 OS=Homo sapiens OX=9606 GN=S100A9 PE=1 SV=1 4.1 2966 - 717560 - - - 0.1395 - 4.232 0.669 - 2450.9 1 2 0 0.0002 15 0 0 0 6.88E+07 0.00E+00 - - - 7.529 0.9996 221125_WJC_METTL3_EV_vs_WT_F05.17272.17272.3 4.70E-05 Sep-68 R.LSLPESTESFHEPSQELK[136.11].F "sp|Q9H2Y7|ZN106_HUMAN,tr|A0A0C4DGM5|A0A0C4DGM5_HUMAN,tr|H3BSS6|H3BSS6_HUMAN" 3 2065.0095 0.69 68571 17272 3 2065.002085 689.3438 Zinc finger protein 106 OS=Homo sapiens OX=9606 GN=ZNF106 PE=1 SV=1 4.48 2966.5 - 326200 - - - -3.5985 - 2.357 0.44 - 89.3 1 2 0 -0.0074 18 0 0 0 3.67E+06 5.28E+06 - - - 5.5785 0.9972 221125_WJC_METTL3_EV_vs_WT_F05.17274.17274.3 0.269 Dec-48 R.DFSAPTLEDHFNK[136.11].T sp|P55081|MFAP1_HUMAN 1 1527.7085 1.43 68573 17274 3 1527.709426 510.2435 Microfibrillar-associated protein 1 OS=Homo sapiens OX=9606 GN=MFAP1 PE=1 SV=2 4.54 2966.8 - 260036 - - - 0.5911 - 1.732 0.232 - 129.5 1 2 0 0.0009 13 0 0 0 3.03E+07 2.11E+07 - - - 2.6156 0.9988 221125_WJC_METTL3_EV_vs_WT_F05.17275.17275.3 0.0244 Aug-40 K.AETDHLFDLSR[166.11].R "sp|Q9NPF5|DMAP1_HUMAN,tr|Q5TG39|Q5TG39_HUMAN,tr|Q5TG38|Q5TG38_HUMAN,tr|Q5TG40|Q5TG40_HUMAN,tr|Q5TG37|Q5TG37_HUMAN" 5 1312.6287 1.14 68574 17275 3 1312.630498 438.5502 DNA methyltransferase 1-associated protein 1 OS=Homo sapiens OX=9606 GN=DMAP1 PE=1 SV=1 4.54 2966.9 - 237175 - - - 1.3698 - 1.655 0.308 - 105.2 1 2 0 0.0018 11 0 0 0 3.32E+06 2.92E+06 - - - 3.4046 0.9944 221125_WJC_METTL3_EV_vs_WT_F05.17277.17277.3 0.00295 Sep-36 K.DKQELEDFIK.Q sp|Q15276|RABE1_HUMAN 1 1263.6347 2.57 68576 17277 3 1263.63306 422.2188 Rab GTPase-binding effector protein 1 OS=Homo sapiens OX=9606 GN=RABEP1 PE=1 SV=2 4.32 2967.2 - 218278 - - - -1.2844 - 1.727 0.281 - 142.6 1 2 1 -0.0016 10 0 0 0 2.06E+06 8.01E+05 - - - 3.2681 1 221125_WJC_METTL3_EV_vs_WT_F05.17281.17281.3 9.79E-10 15/56 K.VIEHIMEDLDTNADK.Q sp|P06702|S10A9_HUMAN 1 1741.8193 135.02 68578 17281 3 1741.821359 581.6137 Protein S100-A9 OS=Homo sapiens OX=9606 GN=S100A9 PE=1 SV=1 4.1 2967.6 - 6.40E+06 - - - 1.2016 - 3.235 0.609 - 351.1 1 2 0 0.0021 15 0 0 0 1.77E+08 1.31E+06 - - - 8.3926 0.9989 221125_WJC_METTL3_EV_vs_WT_F05.17283.17283.3 0.0205 Aug-60 R.HLSSLTDNEQADIFER[166.11].V "sp|O60343|TBCD4_HUMAN,tr|A0A3B3IRT3|A0A3B3IRT3_HUMAN" 2 1883.8889 2.44 68580 17283 3 1883.892934 628.9702 TBC1 domain family member 4 OS=Homo sapiens OX=9606 GN=TBC1D4 PE=1 SV=2 4.31 2967.8 - 1.17E+06 - - - 2.1466 - 1.689 0.352 - 55.9 1 2 0 0.004 16 0 0 0 4.44E+07 1.82E+07 - - - 3.8082 0.9951 221125_WJC_METTL3_EV_vs_WT_F05.17286.17286.3 0.0809 Aug-68 R.LSLPESTESFHEPSQELK.F "sp|Q9H2Y7|ZN106_HUMAN,tr|A0A0C4DGM5|A0A0C4DGM5_HUMAN,tr|H3BSS6|H3BSS6_HUMAN" 3 2056.9953 0.78 68583 17286 3 2056.994397 686.6724 Zinc finger protein 106 OS=Homo sapiens OX=9606 GN=ZNF106 PE=1 SV=1 4.48 2968.2 - 416290 - - - -0.4468 - 1.473 0.246 - 64.1 1 2 0 -0.0009 18 0 0 0 3.60E+06 4.59E+06 - - - 2.2468 0.9999 221125_WJC_METTL3_EV_vs_WT_F05.17287.17287.3 2.55E-07 14/52 R.SDSFENPVLQQHFR.N "sp|P12956|XRCC6_HUMAN,tr|B1AHC9|B1AHC9_HUMAN" 2 1702.8063 1.21 68584 17287 3 1702.810085 568.6094 X-ray repair cross-complementing protein 6 OS=Homo sapiens OX=9606 GN=XRCC6 PE=1 SV=2 5.3 2968.3 - 345829 - - - 2.2034 - 2.511 0.514 - 340.4 1 2 0 0.0038 14 0 0 0 1.68E+08 1.39E+08 - - - 6.7163 1 221125_WJC_METTL3_EV_vs_WT_F05.17290.17290.2 2.34E-06 15/32 K.AEQINQAAGEASAVLAK[136.11].A "sp|Q9UJZ1|STML2_HUMAN,tr|A0A087WYB4|A0A087WYB4_HUMAN,tr|F2Z2I8|F2Z2I8_HUMAN" 3 1677.8777 11.61 68587 17290 2 1677.877093 839.9461 "Stomatin-like protein 2, mitochondrial OS=Homo sapiens OX=9606 GN=STOML2 PE=1 SV=1" 4.53 2968.7 - 241284 - - - -0.3701 - 3.481 0.599 - 578.7 1 2 0 -0.0006 17 0 0 0 1.60E+08 1.37E+07 - - - 6.5316 0.998 221125_WJC_METTL3_EV_vs_WT_F05.17294.17294.2 0.000451 May-34 R.GHVTQDAPIPGSPLYTIK[136.11].A sp|Q15029|U5S1_HUMAN 1 1901.0138 2.82 68591 17294 2 1901.017433 951.5142 116 kDa U5 small nuclear ribonucleoprotein component OS=Homo sapiens OX=9606 GN=EFTUD2 PE=1 SV=1 6.74 2969.2 - 112398 - - - 1.9042 - 1.226 0.392 - 44.6 1 2 0 0.0036 18 0 0 0 3.40E+06 1.20E+06 - - - 2.4361 1 221125_WJC_METTL3_EV_vs_WT_F05.17297.17297.3 1.82E-09 25/76 K.EVVVYLDDNQKPPVGEGLNR.K "sp|P52948|NUP98_HUMAN,tr|A0A3B3ITD8|A0A3B3ITD8_HUMAN" 2 2240.1437 3.03 68592 17297 3 2240.143631 747.7218 Nuclear pore complex protein Nup98-Nup96 OS=Homo sapiens OX=9606 GN=NUP98 PE=1 SV=4 4.32 2969.6 - 1.63E+06 - - - -0.0357 - 4.123 0.657 - 503.6 1 2 0 -0.0001 20 0 0 0 3.55E+08 1.17E+08 - - - 9.3015 1 221125_WJC_METTL3_EV_vs_WT_F05.17298.17298.3 4.32E-05 15/48 R.DFSAPTLEDHFNK.T sp|P55081|MFAP1_HUMAN 1 1519.6943 1.43 68593 17298 3 1519.694569 507.5721 Microfibrillar-associated protein 1 OS=Homo sapiens OX=9606 GN=MFAP1 PE=1 SV=2 4.54 2969.7 - 1.24E+06 - - - 0.1619 - 2.444 0.571 - 228.6 1 2 0 0.0002 13 0 0 0 3.03E+07 2.12E+07 - - - 7.3289 1 221125_WJC_METTL3_EV_vs_WT_F05.17299.17299.3 9.09E-09 23/76 K.EVVVYLDDNQK[136.11]PPVGEGLNR[166.11].K "sp|P52948|NUP98_HUMAN,tr|A0A3B3ITD8|A0A3B3ITD8_HUMAN" 2 2258.1662 2.65 68594 17299 3 2258.165124 753.7293 Nuclear pore complex protein Nup98-Nup96 OS=Homo sapiens OX=9606 GN=NUP98 PE=1 SV=4 4.32 2969.8 - 1.24E+06 - - - -0.4681 - 3.96 0.598 - 404.9 1 2 0 -0.0011 20 0 0 0 3.10E+08 1.17E+08 - - - 8.5456 1 221125_WJC_METTL3_EV_vs_WT_F05.17300.17300.3 5.64E-08 19/64 K.AEQINQAAGEASAVLAK.A "sp|Q9UJZ1|STML2_HUMAN,tr|A0A087WYB4|A0A087WYB4_HUMAN,tr|F2Z2I8|F2Z2I8_HUMAN" 3 1669.8635 1.02 68595 17300 3 1669.864713 557.6284 "Stomatin-like protein 2, mitochondrial OS=Homo sapiens OX=9606 GN=STOML2 PE=1 SV=1" 4.53 2969.9 - 885029 - - - 0.718 - 3.591 0.532 - 784.5 1 2 0 0.0012 17 0 0 0 2.64E+07 2.58E+07 - - - 7.7006 1 221125_WJC_METTL3_EV_vs_WT_F05.17301.17301.3 7.26E-08 14/52 R.SDSFENPVLQQHFR[166.11].N "sp|P12956|XRCC6_HUMAN,tr|B1AHC9|B1AHC9_HUMAN" 2 1712.8146 1.21 68596 17301 3 1712.814808 571.9455 X-ray repair cross-complementing protein 6 OS=Homo sapiens OX=9606 GN=XRCC6 PE=1 SV=2 5.3 2970 - 599922 - - - 0.1197 - 2.678 0.567 - 344.2 1 2 0 0.0002 14 0 0 0 1.69E+08 1.40E+08 - - - 7.4793 0.9999 221125_WJC_METTL3_EV_vs_WT_F05.17304.17304.3 0.000363 Oct-52 K.GC[160.03]WDSIHVVEVQEK[136.11].S "sp|P47756|CAPZB_HUMAN,tr|B1AK87|B1AK87_HUMAN,tr|B1AK88|B1AK88_HUMAN,tr|B1AK85|B1AK85_HUMAN" 4 1692.8021 0.79 68599 17304 3 1692.801916 565.2746 F-actin-capping protein subunit beta OS=Homo sapiens OX=9606 GN=CAPZB PE=1 SV=4 4.65 2970.4 - 498471 - - - -0.1122 - 2.308 0.447 - 137 1 2 0 -0.0002 14 0 0 0 5.29E+06 6.74E+06 - - - 5.7463 1 221125_WJC_METTL3_EV_vs_WT_F05.17306.17306.2 6.41E-07 18/32 K.EIEELQSQAQALSQEGK.S "sp|Q01082|SPTB2_HUMAN,tr|A0A087WUZ3|A0A087WUZ3_HUMAN" 2 1886.9222 2.64 68601 17306 2 1886.920816 944.4684 "Spectrin beta chain, non-erythrocytic 1 OS=Homo sapiens OX=9606 GN=SPTBN1 PE=1 SV=2" 4.09 2970.6 - 393126 - - - -0.7075 - 3.369 0.625 - 1260.4 1 2 0 -0.0013 17 0 0 0 5.43E+06 2.06E+06 - - - 6.643 0.9724 221125_WJC_METTL3_EV_vs_WT_F05.17308.17308.3 0.0932 Sep-60 K.EGKPTIVEEDDPELFK.Q sp|O75937|DNJC8_HUMAN 1 1844.9044 0.59 68603 17308 3 1844.903173 615.9754 DnaJ homolog subfamily C member 8 OS=Homo sapiens OX=9606 GN=DNAJC8 PE=1 SV=2 4.08 2970.9 - 307792 - - - -0.6515 - 1.781 0.106 - 93.2 1 2 0 -0.0012 16 0 0 0 5.79E+06 9.85E+06 - - - 1.2024 1 221125_WJC_METTL3_EV_vs_WT_F05.17310.17310.2 1.19E-08 14/32 K.EIEELQSQAQALSQEGK[136.11].S "sp|Q01082|SPTB2_HUMAN,tr|A0A087WUZ3|A0A087WUZ3_HUMAN" 2 1894.9364 2.61 68605 17310 2 1894.928116 948.4755 "Spectrin beta chain, non-erythrocytic 1 OS=Homo sapiens OX=9606 GN=SPTBN1 PE=1 SV=2" 4.09 2971.2 - 255437 - - - -4.3458 - 3.061 0.6 - 693.9 1 2 0 -0.0082 17 0 0 0 5.38E+06 2.06E+06 - - - 6.2205 0.9997 221125_WJC_METTL3_EV_vs_WT_F05.17311.17311.4 0.000158 14/78 K.EVLLFPAMK[136.11]PEDK[136.11]K[136.11].E sp|Q15046|SYK_HUMAN 1 1667.9383 0.52 68606 17311 4 1667.935755 417.9918 Lysine--tRNA ligase OS=Homo sapiens OX=9606 GN=KARS1 PE=1 SV=3 6.28 2971.3 - 245255 - - - -1.5049 - 2.59 0.343 - 96.9 1 2 0 -0.0025 14 0 0 0 4.10E+06 7.84E+06 - - - 2.5571 0.9999 221125_WJC_METTL3_EV_vs_WT_F05.17312.17312.4 0.00188 14/72 R.ALEHFTDLYDIK[136.11]R[166.11].A "sp|Q00610|CLH1_HUMAN,tr|A0A087WVQ6|A0A087WVQ6_HUMAN" 2 1637.8532 0.76 68607 17312 4 1637.851463 410.4706 Clathrin heavy chain 1 OS=Homo sapiens OX=9606 GN=CLTC PE=1 SV=5 5.38 2971.4 - 236746 - - - -1.077 - 2.374 0.436 - 179.1 1 2 0 -0.0018 13 0 0 0 1.56E+07 2.04E+07 - - - 3.341 1 221125_WJC_METTL3_EV_vs_WT_F05.17316.17316.3 9.18E-07 14/56 R.K[136.11]TEGYSGADISIIVR[166.11].D "sp|Q9UN37|VPS4A_HUMAN,tr|I3L4J1|I3L4J1_HUMAN" 2 1625.8744 0.75 68610 17316 3 1625.87317 542.9654 Vacuolar protein sorting-associated protein 4A OS=Homo sapiens OX=9606 GN=VPS4A PE=1 SV=1 6.07 2971.9 - 313337 - - - -0.7295 - 2.528 0.502 - 281.6 1 2 0 -0.0012 15 0 0 0 4.73E+06 6.31E+06 - - - 6.5565 1 221125_WJC_METTL3_EV_vs_WT_F05.17318.17318.3 2.77E-07 16/68 R.EEPAPEEEEPLLLQRPER.V sp|Q9BVJ6|UT14A_HUMAN 1 2160.0699 2.27 68611 17318 3 2160.070064 721.0306 U3 small nucleolar RNA-associated protein 14 homolog A OS=Homo sapiens OX=9606 GN=UTP14A PE=1 SV=1 4.12 2972.1 - 1.71E+06 - - - 0.0861 - 2.58 0.622 - 255.1 1 2 0 0.0002 18 0 0 0 5.84E+07 2.57E+07 - - - 7.8347 0.9995 221125_WJC_METTL3_EV_vs_WT_F05.17319.17319.4 0.000495 18/96 K.YAINPHLTEDQRFPQLR.L sp|Q9ULX3|NOB1_HUMAN 1 2097.0756 0.66 68612 17319 4 2097.076036 525.2762 RNA-binding protein NOB1 OS=Homo sapiens OX=9606 GN=NOB1 PE=1 SV=1 6.75 2972.2 - 1.10E+06 - - - 0.2213 - 2.945 0.397 - 214.4 1 2 1 0.0005 17 0 0 0 6.05E+06 9.14E+06 - - - 3.0564 1 221125_WJC_METTL3_EV_vs_WT_F05.17322.17322.3 1.75E-05 16/68 R.EEPAPEEEEPLLLQR[166.11]PER[166.11].V sp|Q9BVJ6|UT14A_HUMAN 1 2180.0864 2.27 68615 17322 3 2180.085918 727.7027 U3 small nucleolar RNA-associated protein 14 homolog A OS=Homo sapiens OX=9606 GN=UTP14A PE=1 SV=1 4.12 2972.6 - 830512 - - - -0.2293 - 2.268 0.502 - 226.8 1 2 0 -0.0005 18 0 0 0 5.84E+07 2.57E+07 - - - 6.1758 1 221125_WJC_METTL3_EV_vs_WT_F05.17323.17323.3 0.00197 18/72 R.NEDLLEVGSR[166.11]PGPASQLPR[166.11].F sp|Q96P11|NSUN5_HUMAN 1 2054.066 1.05 68616 17323 3 2054.064121 685.6959 28S rRNA (cytosine-C(5))-methyltransferase OS=Homo sapiens OX=9606 GN=NSUN5 PE=1 SV=2 4.68 2972.7 - 770749 - - - -0.8938 - 2.927 0.478 - 437.3 1 2 0 -0.0018 19 0 0 0 1.57E+07 1.50E+07 - - - 6.5073 1 221125_WJC_METTL3_EV_vs_WT_F05.17325.17325.3 0.00138 18/60 R.ATGISFAIHGNFSGTK.Q "sp|Q15393|SF3B3_HUMAN,tr|H3BMB0|H3BMB0_HUMAN,tr|I3L4G7|I3L4G7_HUMAN" 3 1606.8104 0.34 68618 17325 3 1606.811267 536.6107 Splicing factor 3B subunit 3 OS=Homo sapiens OX=9606 GN=SF3B3 PE=1 SV=4 8.8 2973 - 580336 - - - 0.567 - 3.058 0.414 - 373.5 1 2 0 0.0009 16 0 0 0 1.54E+07 4.46E+07 - - - 6.0235 1 221125_WJC_METTL3_EV_vs_WT_F05.17326.17326.4 0.000139 18/72 R.ALEHFTDLYDIKR.A "sp|Q00610|CLH1_HUMAN,tr|A0A087WVQ6|A0A087WVQ6_HUMAN" 2 1619.8308 0.76 68619 17326 4 1619.829666 405.965 Clathrin heavy chain 1 OS=Homo sapiens OX=9606 GN=CLTC PE=1 SV=5 5.38 2973.1 - 555853 - - - -0.6735 - 3.031 0.529 - 293.3 1 2 0 -0.0011 13 0 0 0 1.55E+07 2.04E+07 - - - 4.2413 1 221125_WJC_METTL3_EV_vs_WT_F05.17327.17327.2 4.91E-09 15/28 K.NQVALNPQNTVFDAK.R "sp|P0DMV8|HS71A_HUMAN,sp|P0DMV9|HS71B_HUMAN,tr|A0A0G2JIW1|A0A0G2JIW1_HUMAN" 3 1657.8424 0.17 68620 17327 2 1657.843278 829.9285 Heat shock 70 kDa protein 1A OS=Homo sapiens OX=9606 GN=HSPA1A PE=1 SV=1 5.84 2973.2 - 466770 - - - 0.5393 - 2.94 0.639 - 557.8 1 2 0 0.0009 15 0 0 0 4.76E+08 2.85E+09 - - - 6.4117 1 221125_WJC_METTL3_EV_vs_WT_F05.17328.17328.3 5.91E-06 15/68 R.VAPEEHPVLLTEAPLNPK[136.11].A "sp|P63261|ACTG_HUMAN,sp|P60709|ACTB_HUMAN,tr|A0A804GS07|A0A804GS07_HUMAN,tr|I3L3I0|I3L3I0_HUMAN,tr|G5E9R0|G5E9R0_HUMAN,tr|E7EVS6|E7EVS6_HUMAN,tr|A0A6Q8PFE4|A0A6Q8PFE4_HUMAN,tr|J3KT65|J3KT65_HUMAN,tr|I3L3R2|I3L3R2_HUMAN,tr|K7EM38|K7EM38_HUMAN,tr|A0A6Q8PH58|A0A6Q8PH58_HUMAN,tr|I3L1U9|I3L1U9_HUMAN,tr|A0A2R8Y793|A0A2R8Y793_HUMAN,tr|I3L4N8|I3L4N8_HUMAN,tr|A0A2R8YGF8|A0A2R8YGF8_HUMAN" 15 1961.0713 1.2 68621 17328 3 1961.070761 654.6977 "Actin, cytoplasmic 2 OS=Homo sapiens OX=9606 GN=ACTG1 PE=1 SV=1" 4.75 2973.4 - 433956 - - - -0.2891 - 2.938 0.458 - 235.7 1 2 0 -0.0006 18 0 0 0 1.72E+08 1.44E+08 - - - 6.3297 1 221125_WJC_METTL3_EV_vs_WT_F05.17329.17329.3 1.71E-13 19/76 R.PQPDPNAEFDPDLPGGGLHR[166.11].C "sp|O00488|ZN593_HUMAN,tr|A9J4F5|A9J4F5_HUMAN" 2 2138.0057 3.27 68622 17329 3 2137.997836 713.6758 Zinc finger protein 593 OS=Homo sapiens OX=9606 GN=ZNF593 PE=1 SV=2 4.22 2973.5 - 429320 - - - -3.6553 - 3.451 0.696 - 324.6 1 1 0 -0.0078 20 0 0 0 8.68E+07 2.65E+07 - - - 9.3026 0.9999 221125_WJC_METTL3_EV_vs_WT_F05.17330.17330.2 6.42E-05 14/28 K.SQPEPSPVLSQLSQR.Q sp|Q5T6F2|UBAP2_HUMAN 1 1651.8529 1.16 68623 17330 2 1651.85212 826.9338 Ubiquitin-associated protein 2 OS=Homo sapiens OX=9606 GN=UBAP2 PE=1 SV=1 5.72 2973.6 - 344066 - - - -0.5019 - 2.19 0.52 - 515.5 1 2 0 -0.0008 15 0 0 0 1.97E+07 1.70E+07 - - - 4.8087 1 221125_WJC_METTL3_EV_vs_WT_F05.17335.17335.3 5.66E-08 13/64 K.VTHAVVTVPAYFNDAQR[166.11].Q "sp|P11021|BIP_HUMAN,tr|A0A7P0TB36|A0A7P0TB36_HUMAN,tr|A0A7P0TAI0|A0A7P0TAI0_HUMAN" 3 1896.9722 0.55 68627 17335 3 1896.97164 633.3313 Endoplasmic reticulum chaperone BiP OS=Homo sapiens OX=9606 GN=HSPA5 PE=1 SV=2 6.71 2974.2 - 3.82E+06 - - - -0.2773 - 2.756 0.58 - 287 1 2 0 -0.0005 17 0 0 0 4.34E+08 7.95E+08 - - - 7.5674 0.9998 221125_WJC_METTL3_EV_vs_WT_F05.17337.17337.3 0.115 14/68 R.VAPEEHPVLLTEAPLNPK.A "sp|P63261|ACTG_HUMAN,sp|P60709|ACTB_HUMAN,tr|A0A804GS07|A0A804GS07_HUMAN,tr|I3L3I0|I3L3I0_HUMAN,tr|G5E9R0|G5E9R0_HUMAN,tr|E7EVS6|E7EVS6_HUMAN,tr|A0A6Q8PFE4|A0A6Q8PFE4_HUMAN,tr|J3KT65|J3KT65_HUMAN,tr|I3L3R2|I3L3R2_HUMAN,tr|K7EM38|K7EM38_HUMAN,tr|A0A6Q8PH58|A0A6Q8PH58_HUMAN,tr|I3L1U9|I3L1U9_HUMAN,tr|A0A2R8Y793|A0A2R8Y793_HUMAN,tr|I3L4N8|I3L4N8_HUMAN,tr|A0A2R8YGF8|A0A2R8YGF8_HUMAN" 15 1953.0571 1.2 68629 17337 3 1953.056732 652.0263 "Actin, cytoplasmic 2 OS=Homo sapiens OX=9606 GN=ACTG1 PE=1 SV=1" 4.75 2974.4 - 1.33E+06 - - - -0.2028 - 2.53 0.343 - 244.4 1 2 0 -0.0004 18 0 0 0 1.72E+08 1.44E+08 - - - 4.6754 1 221125_WJC_METTL3_EV_vs_WT_F05.17338.17338.2 2.04E-09 14/30 R.GSAFAIGSDGLC[160.03]C[160.03]QSR.E "sp|Q92499|DDX1_HUMAN,tr|A0A7I2V2M5|A0A7I2V2M5_HUMAN,tr|A0A087X2G1|A0A087X2G1_HUMAN,tr|A0A7I2V430|A0A7I2V430_HUMAN,tr|A0A7I2V421|A0A7I2V421_HUMAN,tr|A0A7I2V4F0|A0A7I2V4F0_HUMAN,tr|A0A7I2V4Q0|A0A7I2V4Q0_HUMAN,tr|A0A7I2YQD0|A0A7I2YQD0_HUMAN,tr|A0A7I2V5X8|A0A7I2V5X8_HUMAN,tr|A0A7I2V4J3|A0A7I2V4J3_HUMAN,tr|A0A087WZ71|A0A087WZ71_HUMAN,tr|A0A7I2YQ77|A0A7I2YQ77_HUMAN" 12 1684.7297 1.57 68630 17338 2 1684.728737 843.3721 ATP-dependent RNA helicase DDX1 OS=Homo sapiens OX=9606 GN=DDX1 PE=1 SV=2 5.82 2974.5 - 915984 - - - -0.5948 - 2.639 0.682 - 439.9 1 2 0 -0.001 16 0 0 0 1.22E+08 7.72E+07 - - - 6.4637 1 221125_WJC_METTL3_EV_vs_WT_F05.17340.17340.2 2.82E-10 14/30 R.EEIQSSISGVTAAYNR[166.11].E "sp|P46940|IQGA1_HUMAN,tr|A0A087WWP1|A0A087WWP1_HUMAN,tr|H0YLE8|H0YLE8_HUMAN,tr|A0A0J9YXZ5|A0A0J9YXZ5_HUMAN" 4 1733.846 1.15 68632 17340 2 1733.844992 867.9303 Ras GTPase-activating-like protein IQGAP1 OS=Homo sapiens OX=9606 GN=IQGAP1 PE=1 SV=1 4.53 2974.8 - 676166 - - - -0.56 - 3.081 0.678 - 618.6 1 2 0 -0.001 16 0 0 0 1.03E+07 8.92E+06 - - - 6.8149 1 221125_WJC_METTL3_EV_vs_WT_F05.17341.17341.2 5.96E-06 17/30 R.EEIQSSISGVTAAYNR.E "sp|P46940|IQGA1_HUMAN,tr|A0A087WWP1|A0A087WWP1_HUMAN,tr|H0YLE8|H0YLE8_HUMAN,tr|A0A0J9YXZ5|A0A0J9YXZ5_HUMAN" 4 1723.8377 1.15 68633 17341 2 1723.840182 862.9261 Ras GTPase-activating-like protein IQGAP1 OS=Homo sapiens OX=9606 GN=IQGAP1 PE=1 SV=1 4.53 2974.9 - 561610 - - - 1.4439 - 3.329 0.587 - 985.1 1 2 0 0.0025 16 0 0 0 1.03E+07 8.92E+06 - - - 6.3326 1 221125_WJC_METTL3_EV_vs_WT_F05.17343.17343.2 3.61E-15 16/34 R.DPDAQPGGELMLGGTDSK.Y "sp|P07339|CATD_HUMAN,tr|A0A1B0GW44|A0A1B0GW44_HUMAN,tr|A0A1B0GVD5|A0A1B0GVD5_HUMAN,tr|A0A1B0GV23|A0A1B0GV23_HUMAN,tr|C9JH19|C9JH19_HUMAN,tr|H7C469|H7C469_HUMAN,tr|A0A1B0GWE8|A0A1B0GWE8_HUMAN,tr|A0A1B0GU03|A0A1B0GU03_HUMAN,tr|A0A1B0GVP3|A0A1B0GVP3_HUMAN,tr|F8WD96|F8WD96_HUMAN,tr|A0A1B0GU92|A0A1B0GU92_HUMAN,tr|F8W787|F8W787_HUMAN" 12 1786.8043 3 68635 17343 2 1786.799386 894.4094 Cathepsin D OS=Homo sapiens OX=9606 GN=CTSD PE=1 SV=1 3.84 2975.2 - 456046 - - - -2.7748 - 3.051 0.77 - 699.4 1 2 0 -0.005 18 0 0 0 3.33E+07 1.11E+07 - - - 7.4691 1 221125_WJC_METTL3_EV_vs_WT_F05.17348.17348.2 2.74E-08 15/30 R.GSAFAIGSDGLC[160.03]C[160.03]QSR[166.11].E "sp|Q92499|DDX1_HUMAN,tr|A0A7I2V2M5|A0A7I2V2M5_HUMAN,tr|A0A087X2G1|A0A087X2G1_HUMAN,tr|A0A7I2V430|A0A7I2V430_HUMAN,tr|A0A7I2V421|A0A7I2V421_HUMAN,tr|A0A7I2V4F0|A0A7I2V4F0_HUMAN,tr|A0A7I2V4Q0|A0A7I2V4Q0_HUMAN,tr|A0A7I2YQD0|A0A7I2YQD0_HUMAN,tr|A0A7I2V5X8|A0A7I2V5X8_HUMAN,tr|A0A7I2V4J3|A0A7I2V4J3_HUMAN,tr|A0A087WZ71|A0A087WZ71_HUMAN,tr|A0A7I2YQ77|A0A7I2YQ77_HUMAN" 12 1694.738 1.57 68638 17348 2 1694.735973 848.3763 ATP-dependent RNA helicase DDX1 OS=Homo sapiens OX=9606 GN=DDX1 PE=1 SV=2 5.82 2975.8 - 1.96E+06 - - - -1.2014 - 2.992 0.635 - 600.5 1 2 0 -0.002 16 0 0 0 1.22E+08 7.72E+07 - - - 6.4249 0.9999 221125_WJC_METTL3_EV_vs_WT_F05.17349.17349.3 1.44E-06 Oct-60 K.TSEVPYAGINIGPVHK[136.11].K "sp|O60841|IF2P_HUMAN,tr|A0A087WUT6|A0A087WUT6_HUMAN" 2 1688.8977 1.32 68639 17349 3 1688.900031 563.9732 Eukaryotic translation initiation factor 5B OS=Homo sapiens OX=9606 GN=EIF5B PE=1 SV=4 6.41 2975.8 - 1.33E+06 - - - 1.3678 - 2.159 0.506 - 136.9 1 2 0 0.0023 16 0 0 0 2.48E+07 1.88E+07 - - - 6.1556 0.9423 221125_WJC_METTL3_EV_vs_WT_F05.17350.17350.3 0.986 Sep-56 R.ETNLDSLPLVDTHSK.R sp|P08670|VIME_HUMAN 1 1667.8366 2.19 68640 17350 3 1667.840715 556.9528 Vimentin OS=Homo sapiens OX=9606 GN=VIM PE=1 SV=4 4.54 2975.9 - 3.37E+06 - - - 2.4493 - 1.668 0.129 - 90 1 2 0 0.0041 15 0 0 0 8.56E+09 3.90E+09 - - - 1.3121 1 221125_WJC_METTL3_EV_vs_WT_F05.17351.17351.3 7.56E-11 21/68 R.R[166.11]LEASETESFGNEIYTVK[136.11].F "sp|O43148|MCES_HUMAN,tr|K7EP06|K7EP06_HUMAN" 2 2090.0287 1.17 68641 17351 3 2090.031113 697.6835 mRNA cap guanine-N7 methyltransferase OS=Homo sapiens OX=9606 GN=RNMT PE=1 SV=1 4.49 2976 - 1.18E+06 - - - 1.1617 - 4.373 0.672 - 694.6 1 2 0 0.0024 18 0 0 0 1.63E+07 1.39E+07 - - - 9.7055 0.9729 221125_WJC_METTL3_EV_vs_WT_F05.17353.17353.3 0.00481 13/60 K.EGK[136.11]PTIVEEDDPELFK[136.11].Q sp|O75937|DNJC8_HUMAN 1 1860.9328 0.63 68643 17353 3 1860.920875 621.3182 DnaJ homolog subfamily C member 8 OS=Homo sapiens OX=9606 GN=DNAJC8 PE=1 SV=2 4.08 2976.2 - 1.06E+06 - - - -6.3946 - 2.149 0.28 - 82.1 1 2 0 -0.0119 16 0 0 0 5.79E+06 9.15E+06 - - - 3.6213 1 221125_WJC_METTL3_EV_vs_WT_F05.17355.17355.3 3.31E-05 15/52 K.QIGNVAALPGIVHR.S sp|Q9Y3I0|RTCB_HUMAN 1 1443.831 1.99 68645 17355 3 1443.830847 482.2843 RNA-splicing ligase RtcB homolog OS=Homo sapiens OX=9606 GN=RTCB PE=1 SV=1 9.76 2976.5 - 642691 - - - -0.1281 - 2.764 0.425 - 289.7 1 2 0 -0.0002 14 0 0 0 5.68E+06 2.85E+06 - - - 5.9801 0.9998 221125_WJC_METTL3_EV_vs_WT_F05.17359.17359.3 4.04E-06 Nov-56 R.ETNLDSLPLVDTHSK[136.11].R sp|P08670|VIME_HUMAN 1 1675.8508 2.14 68647 17359 3 1675.85023 559.6242 Vimentin OS=Homo sapiens OX=9606 GN=VIM PE=1 SV=4 4.54 2976.9 - 1.97E+06 - - - -0.358 - 2.181 0.38 - 197.4 1 2 0 -0.0006 15 0 0 0 8.31E+09 3.88E+09 - - - 4.8112 1 221125_WJC_METTL3_EV_vs_WT_F05.17360.17360.3 1.00E-05 29/68 R.HAIYDKLDDDGLIAPGVR.V "sp|P30876|RPB2_HUMAN,tr|C9J4M6|C9J4M6_HUMAN,tr|C9J2Y9|C9J2Y9_HUMAN" 3 1967.0112 1.96 68648 17360 3 1967.008625 656.6777 DNA-directed RNA polymerase II subunit RPB2 OS=Homo sapiens OX=9606 GN=POLR2B PE=1 SV=1 4.56 2977 - 1.49E+06 - - - -1.3294 - 4.348 0.616 - 1221.4 1 2 1 -0.0026 18 0 0 0 1.34E+07 6.84E+06 - - - 9.0668 0.9999 221125_WJC_METTL3_EV_vs_WT_F05.17362.17362.4 1.53E-05 20/102 R.HAIYDKLDDDGLIAPGVR.V "sp|P30876|RPB2_HUMAN,tr|C9J4M6|C9J4M6_HUMAN,tr|C9J2Y9|C9J2Y9_HUMAN" 3 1967.0112 0.77 68650 17362 4 1967.009484 492.7601 DNA-directed RNA polymerase II subunit RPB2 OS=Homo sapiens OX=9606 GN=POLR2B PE=1 SV=1 4.56 2977.2 - 920283 - - - -0.8927 - 3.216 0.547 - 298.9 1 2 1 -0.0018 18 0 0 0 9.43E+06 1.23E+07 - - - 4.3868 0.9996 221125_WJC_METTL3_EV_vs_WT_F05.17365.17365.2 6.47E-05 24-Oct K.DEILPTTPISEQK[136.11].G "sp|P23396|RS3_HUMAN,tr|H0YEU2|H0YEU2_HUMAN,tr|E9PSF4|E9PSF4_HUMAN,tr|E9PL09|E9PL09_HUMAN,tr|E9PPU1|E9PPU1_HUMAN" 5 1477.7755 0.77 68653 17365 2 1477.777806 739.895 40S ribosomal protein S3 OS=Homo sapiens OX=9606 GN=RPS3 PE=1 SV=2 4.14 2977.6 - 576316 - - - 1.5334 - 1.837 0.44 - 256.3 1 2 0 0.0023 13 0 0 0 2.55E+07 3.31E+07 - - - 3.8509 1 221125_WJC_METTL3_EV_vs_WT_F05.17373.17373.3 4.43E-10 22/76 K.VNNSSLIGVGYTQTLR[166.11]PGVK[136.11].L "sp|P45880|VDAC2_HUMAN,tr|A0A0A0MR02|A0A0A0MR02_HUMAN" 2 2120.1709 1.29 68659 17373 3 2120.168747 707.7309 Voltage-dependent anion-selective channel protein 2 OS=Homo sapiens OX=9606 GN=VDAC2 PE=1 SV=2 9.99 2978.4 - 2.74E+06 - - - -1.0027 - 4.061 0.62 - 655.1 1 2 0 -0.0021 20 0 0 0 5.91E+08 4.58E+08 - - - 8.8517 1 221125_WJC_METTL3_EV_vs_WT_F05.17374.17374.3 4.05E-08 26/76 K.VNNSSLIGVGYTQTLRPGVK.L "sp|P45880|VDAC2_HUMAN,tr|A0A0A0MR02|A0A0A0MR02_HUMAN" 2 2102.1484 1.29 68660 17374 3 2102.147317 701.7234 Voltage-dependent anion-selective channel protein 2 OS=Homo sapiens OX=9606 GN=VDAC2 PE=1 SV=2 9.99 2978.5 - 3.27E+06 - - - -0.5166 - 4.539 0.639 - 1107.9 1 2 0 -0.0011 20 0 0 0 5.91E+08 4.58E+08 - - - 9.3338 1 221125_WJC_METTL3_EV_vs_WT_F05.17375.17375.2 5.74E-10 16/30 R.QQVAFYGQTLGQAQAH.S sp|Q96I24|FUBP3_HUMAN 1 1745.8485 - 68661 17375 2 1745.846414 873.9315 Far upstream element-binding protein 3 OS=Homo sapiens OX=9606 GN=FUBP3 PE=1 SV=2 6.74 2978.6 - 1.78E+06 - - - -1.2132 - 3.146 0.67 - 759.8 1 1 0 -0.0021 16 0 0 0 - - - - - 6.8068 1 221125_WJC_METTL3_EV_vs_WT_F05.17376.17376.3 6.72E-13 24/76 R.PQPDPNAEFDPDLPGGGLHR.C "sp|O00488|ZN593_HUMAN,tr|A9J4F5|A9J4F5_HUMAN" 2 2127.9974 1.63 68662 17376 3 2127.994332 710.3397 Zinc finger protein 593 OS=Homo sapiens OX=9606 GN=ZNF593 PE=1 SV=2 4.22 2978.7 - 1.67E+06 - - - -1.4328 - 3.815 0.72 - 522 1 1 0 -0.0031 20 0 0 0 3.96E+07 2.43E+07 - - - 9.8147 1 221125_WJC_METTL3_EV_vs_WT_F05.17379.17379.3 1.56E-10 19/84 K.VPEIEVTVEGPNNNNPQTSAVR.T "sp|P78347|GTF2I_HUMAN,tr|A0A494C1K3|A0A494C1K3_HUMAN" 2 2363.1717 1.79 68665 17379 3 2363.168961 788.7312 General transcription factor II-I OS=Homo sapiens OX=9606 GN=GTF2I PE=1 SV=2 4.25 2979.1 - 735302 - - - -1.1662 - 3.152 0.547 - 152.3 1 2 0 -0.0028 22 0 0 0 1.69E+08 9.48E+07 - - - 7.3596 0.9999 221125_WJC_METTL3_EV_vs_WT_F05.17380.17380.2 8.36E-05 24-Dec K.DEILPTTPISEQK.G "sp|P23396|RS3_HUMAN,tr|H0YEU2|H0YEU2_HUMAN,tr|E9PSF4|E9PSF4_HUMAN,tr|E9PL09|E9PL09_HUMAN,tr|E9PPU1|E9PPU1_HUMAN" 5 1469.7613 0.77 68666 17380 2 1469.76143 735.8879 40S ribosomal protein S3 OS=Homo sapiens OX=9606 GN=RPS3 PE=1 SV=2 4.14 2979.3 - 719069 - - - 0.0612 - 2.158 0.498 - 398.2 1 2 0 0.0001 13 0 0 0 2.55E+07 3.31E+07 - - - 4.6933 1 221125_WJC_METTL3_EV_vs_WT_F05.17385.17385.3 9.15E-08 16/52 R.K[136.11]GVEGLIDIENPNR[166.11].V sp|Q13442|HAP28_HUMAN 1 1570.8434 0.68 68669 17385 3 1570.840626 524.6217 28 kDa heat- and acid-stable phosphoprotein OS=Homo sapiens OX=9606 GN=PDAP1 PE=1 SV=1 4.68 2979.8 - 1.13E+06 - - - -1.7596 - 2.807 0.577 - 434.2 1 2 0 -0.0028 14 0 0 0 2.90E+07 4.24E+07 - - - 7.7151 1 221125_WJC_METTL3_EV_vs_WT_F05.17386.17386.3 2.12E-14 20/68 K.FYC[160.03]DYC[160.03]DTYLTHDSPSVR[166.11].K "sp|P09234|RU1C_HUMAN,tr|A0A0A0MRR7|A0A0A0MRR7_HUMAN" 2 2307.944 1.06 68670 17386 3 2307.938135 770.322 U1 small nuclear ribonucleoprotein C OS=Homo sapiens OX=9606 GN=SNRPC PE=1 SV=1 4.41 2979.9 - 1.23E+06 - - - -2.5581 - 3.24 0.798 - 414.9 1 2 0 -0.0059 18 0 0 0 2.11E+07 1.99E+07 - - - 10.3626 0.9998 221125_WJC_METTL3_EV_vs_WT_F05.17387.17387.3 0.000106 13/60 R.GSAFAIGSDGLC[160.03]C[160.03]QSR.E "sp|Q92499|DDX1_HUMAN,tr|A0A7I2V2M5|A0A7I2V2M5_HUMAN,tr|A0A087X2G1|A0A087X2G1_HUMAN,tr|A0A7I2V430|A0A7I2V430_HUMAN,tr|A0A7I2V421|A0A7I2V421_HUMAN,tr|A0A7I2V4F0|A0A7I2V4F0_HUMAN,tr|A0A7I2V4Q0|A0A7I2V4Q0_HUMAN,tr|A0A7I2YQD0|A0A7I2YQD0_HUMAN,tr|A0A7I2V5X8|A0A7I2V5X8_HUMAN,tr|A0A7I2V4J3|A0A7I2V4J3_HUMAN,tr|A0A087WZ71|A0A087WZ71_HUMAN,tr|A0A7I2YQ77|A0A7I2YQ77_HUMAN" 12 1684.7297 2.26 68671 17387 3 1684.728149 562.5839 ATP-dependent RNA helicase DDX1 OS=Homo sapiens OX=9606 GN=DDX1 PE=1 SV=2 5.82 2980 - 1.22E+06 - - - -0.9438 - 2.273 0.372 - 114.7 1 2 0 -0.0016 16 0 0 0 1.53E+07 6.78E+06 - - - 4.7938 1 221125_WJC_METTL3_EV_vs_WT_F05.17392.17392.3 1.38E-07 15/56 K.NQVALNPQNTVFDAK.R "sp|P0DMV8|HS71A_HUMAN,sp|P0DMV9|HS71B_HUMAN,tr|A0A0G2JIW1|A0A0G2JIW1_HUMAN" 3 1657.8424 0.4 68674 17392 3 1657.840707 553.6214 Heat shock 70 kDa protein 1A OS=Homo sapiens OX=9606 GN=HSPA1A PE=1 SV=1 5.84 2980.7 - 1.38E+06 - - - -1.0116 - 3.209 0.557 - 413.1 1 2 0 -0.0017 15 0 0 0 1.30E+08 3.25E+08 - - - 7.792 0.9958 221125_WJC_METTL3_EV_vs_WT_F05.17396.17396.3 1.54E-07 19/60 R.QQVAFYGQTLGQAQAH.S sp|Q96I24|FUBP3_HUMAN 1 1745.8485 - 68676 17396 3 1745.844285 582.9568 Far upstream element-binding protein 3 OS=Homo sapiens OX=9606 GN=FUBP3 PE=1 SV=2 6.74 2981.2 - 3.61E+06 - - - -2.4326 - 3.057 0.537 - 521.9 1 1 0 -0.0042 16 0 0 0 - - - - - 7.393 1 221125_WJC_METTL3_EV_vs_WT_F05.17399.17399.3 5.41E-14 20/88 R.AELAAAAVGSSTTSINVPAAASK.L "sp|Q9BSJ2|GCP2_HUMAN,tr|A0A804HLH6|A0A804HLH6_HUMAN,tr|A0A804HJH7|A0A804HJH7_HUMAN,tr|F2Z2B9|F2Z2B9_HUMAN,tr|A0A804HK74|A0A804HK74_HUMAN,tr|A0A804HL95|A0A804HL95_HUMAN,tr|A0A804HJ08|A0A804HJ08_HUMAN,tr|A0A804HJQ4|A0A804HJQ4_HUMAN,tr|A0A804HJS9|A0A804HJS9_HUMAN,tr|A0A804HI27|A0A804HI27_HUMAN" 10 2086.0906 2.19 68679 17399 3 2086.089618 696.3708 Gamma-tubulin complex component 2 OS=Homo sapiens OX=9606 GN=TUBGCP2 PE=1 SV=2 6.05 2981.5 - 552656 - - - -0.477 - 3.681 0.628 - 391.4 1 2 0 -0.001 23 0 0 0 1.31E+07 5.95E+06 - - - 8.5985 0.9987 221125_WJC_METTL3_EV_vs_WT_F05.17403.17403.3 9.45E-06 25/76 Q.AIAAQNAAVQAVNAHSNILK.A "sp|Q16891|MIC60_HUMAN,tr|B9A067|B9A067_HUMAN,tr|C9J406|C9J406_HUMAN,tr|H7C463|H7C463_HUMAN" 4 2003.0912 1.91 68681 17403 3 2003.088714 668.7044 MICOS complex subunit MIC60 OS=Homo sapiens OX=9606 GN=IMMT PE=1 SV=1 8.8 2982 - 1.57E+06 - - - -1.2521 - 4.235 0.543 - 548.2 1 1 0 -0.0025 20 0 0 0 5.35E+07 2.80E+07 - - - 8.0949 1 221125_WJC_METTL3_EV_vs_WT_F05.17404.17404.2 1.12E-08 15/38 K.GGAEEPGAEELLGPPAPGDK.G sp|P50219|MNX1_HUMAN 1 1889.9007 6.87 68682 17404 2 1889.893898 945.9576 Motor neuron and pancreas homeobox protein 1 OS=Homo sapiens OX=9606 GN=MNX1 PE=1 SV=3 3.91 2982.1 - 554473 - - - -3.5923 - 3.039 0.649 - 504.2 1 2 0 -0.0068 20 0 0 0 1.14E+08 1.65E+07 - - - 6.5651 0.9986 221125_WJC_METTL3_EV_vs_WT_F05.17405.17405.3 9.03E-07 23/76 Q.AIAAQNAAVQAVNAHSNILK[136.11].A "sp|Q16891|MIC60_HUMAN,tr|B9A067|B9A067_HUMAN,tr|C9J406|C9J406_HUMAN,tr|H7C463|H7C463_HUMAN" 4 2011.1054 1.91 68683 17405 3 2011.103796 671.3758 MICOS complex subunit MIC60 OS=Homo sapiens OX=9606 GN=IMMT PE=1 SV=1 8.8 2982.3 - 815995 - - - -0.8085 - 4.189 0.516 - 545.3 1 1 0 -0.0016 20 0 0 0 5.35E+07 2.80E+07 - - - 7.7676 0.9999 221125_WJC_METTL3_EV_vs_WT_F05.17407.17407.3 0.000293 Dec-60 R.GSAFAIGSDGLC[160.03]C[160.03]QSR[166.11].E "sp|Q92499|DDX1_HUMAN,tr|A0A7I2V2M5|A0A7I2V2M5_HUMAN,tr|A0A087X2G1|A0A087X2G1_HUMAN,tr|A0A7I2V430|A0A7I2V430_HUMAN,tr|A0A7I2V421|A0A7I2V421_HUMAN,tr|A0A7I2V4F0|A0A7I2V4F0_HUMAN,tr|A0A7I2V4Q0|A0A7I2V4Q0_HUMAN,tr|A0A7I2YQD0|A0A7I2YQD0_HUMAN,tr|A0A7I2V5X8|A0A7I2V5X8_HUMAN,tr|A0A7I2V4J3|A0A7I2V4J3_HUMAN,tr|A0A087WZ71|A0A087WZ71_HUMAN,tr|A0A7I2YQ77|A0A7I2YQ77_HUMAN" 12 1694.738 2.26 68685 17407 3 1694.739055 565.9199 ATP-dependent RNA helicase DDX1 OS=Homo sapiens OX=9606 GN=DDX1 PE=1 SV=2 5.82 2982.5 - 329291 - - - 0.6172 - 1.919 0.452 - 135.7 1 2 0 0.001 16 0 0 0 1.53E+07 6.78E+06 - - - 5.2515 1 221125_WJC_METTL3_EV_vs_WT_F05.17420.17420.3 1.51E-12 23/84 K.VPEIEVTVEGPNNNNPQTSAVR[166.11].T "sp|P78347|GTF2I_HUMAN,tr|A0A494C1K3|A0A494C1K3_HUMAN" 2 2373.18 1.79 68692 17420 3 2373.171696 792.0673 General transcription factor II-I OS=Homo sapiens OX=9606 GN=GTF2I PE=1 SV=2 4.25 2984.1 - 2.95E+06 - - - -3.4936 - 4.277 0.655 - 479.6 1 2 0 -0.0083 22 0 0 0 1.69E+08 9.48E+07 - - - 9.2857 1 221125_WJC_METTL3_EV_vs_WT_F05.17422.17422.2 8.07E-11 16/38 K.GGAEEPGAEELLGPPAPGDK[136.11].G sp|P50219|MNX1_HUMAN 1 1897.9149 8.18 68694 17422 2 1898.908592 949.9647 Motor neuron and pancreas homeobox protein 1 OS=Homo sapiens OX=9606 GN=MNX1 PE=1 SV=3 3.91 2984.3 - 405920 - - - 523.5772 - 2.877 0.642 - 557.9 1 2 0 0.9937 20 0 0 0 7.58E+07 9.27E+06 - - - 6.0689 0.9999 221125_WJC_METTL3_EV_vs_WT_F05.17425.17425.3 5.62E-05 22/64 R.EQTLSPTITSGLHNIAR[166.11].S "sp|O94979|SC31A_HUMAN,tr|H0Y8W8|H0Y8W8_HUMAN,tr|H7BXG7|H7BXG7_HUMAN,tr|D6REX3|D6REX3_HUMAN" 4 1846.9776 0.001 68695 17425 3 1846.971346 616.6665 Protein transport protein Sec31A OS=Homo sapiens OX=9606 GN=SEC31A PE=1 SV=3 6.85 2984.7 - 900579 - - - -3.411 - 3.596 0.581 - 753.9 1 2 0 -0.0063 17 0 0 0 0.00E+00 3.25E+07 - - - 8.249 1 221125_WJC_METTL3_EV_vs_WT_F05.17427.17427.3 6.93E-05 14/52 R.KGVEGLIDIENPNR.V sp|Q13442|HAP28_HUMAN 1 1552.8209 0.69 68697 17427 3 1552.82345 518.6142 28 kDa heat- and acid-stable phosphoprotein OS=Homo sapiens OX=9606 GN=PDAP1 PE=1 SV=1 4.68 2985 - 1.01E+06 - - - 1.6293 - 2.782 0.472 - 273.6 1 2 0 0.0025 14 0 0 0 2.94E+07 4.26E+07 - - - 6.5207 1 221125_WJC_METTL3_EV_vs_WT_F05.17428.17428.4 1.65E-09 22/120 K.AVAFQNPQTHVIENLHAAAYR.N "sp|P22695|QCR2_HUMAN,tr|H3BP04|H3BP04_HUMAN,tr|H3BRG4|H3BRG4_HUMAN,tr|H3BSJ9|H3BSJ9_HUMAN" 4 2349.1978 1.51 68698 17428 4 2349.196659 588.3067 "Cytochrome b-c1 complex subunit 2, mitochondrial OS=Homo sapiens OX=9606 GN=UQCRC2 PE=1 SV=3" 6.96 2985.1 - 979436 - - - -0.4912 - 4.343 0.591 - 296.7 1 2 0 -0.0012 21 0 0 0 1.13E+08 7.49E+07 - - - 4.8553 1 221125_WJC_METTL3_EV_vs_WT_F05.17435.17435.4 2.24E-09 24/120 K.AVAFQNPQTHVIENLHAAAYR[166.11].N "sp|P22695|QCR2_HUMAN,tr|H3BP04|H3BP04_HUMAN,tr|H3BRG4|H3BRG4_HUMAN,tr|H3BSJ9|H3BSJ9_HUMAN" 4 2359.2061 1.52 68702 17435 4 2359.203767 590.8088 "Cytochrome b-c1 complex subunit 2, mitochondrial OS=Homo sapiens OX=9606 GN=UQCRC2 PE=1 SV=3" 6.96 2986 - 1.14E+06 - - - -0.9813 - 4.123 0.531 - 438.9 1 2 0 -0.0023 21 0 0 0 1.14E+08 7.49E+07 - - - 4.3156 1 221125_WJC_METTL3_EV_vs_WT_F05.17441.17441.2 1.25E-08 28-Dec K.AGSSWQC[160.03]DTC[160.03]LLQNK.V sp|P49790|NU153_HUMAN 1 1766.7716 2.02 68705 17441 2 1766.768583 884.3931 Nuclear pore complex protein Nup153 OS=Homo sapiens OX=9606 GN=NUP153 PE=1 SV=2 5.86 2986.8 - 275316 - - - -1.7099 - 2.472 0.699 - 504.1 1 2 0 -0.003 15 0 0 0 5.02E+07 2.48E+07 - - - 6.4279 1 221125_WJC_METTL3_EV_vs_WT_F05.17445.17445.2 4.34E-10 16/28 K.NQVALNPQNTVFDAK[136.11].R "sp|P0DMV8|HS71A_HUMAN,sp|P0DMV9|HS71B_HUMAN,tr|A0A0G2JIW1|A0A0G2JIW1_HUMAN" 3 1665.8566 0.17 68707 17445 2 1665.853568 833.9356 Heat shock 70 kDa protein 1A OS=Homo sapiens OX=9606 GN=HSPA1A PE=1 SV=1 5.84 2987.3 - 5.09E+07 - - - -1.8105 - 3.21 0.661 - 642 1 2 0 -0.003 15 0 0 0 4.76E+08 2.85E+09 - - - 6.7895 1 221125_WJC_METTL3_EV_vs_WT_F05.17451.17451.2 1.66E-10 14/28 K.AGSSWQC[160.03]DTC[160.03]LLQNK[136.11].V sp|P49790|NU153_HUMAN 1 1774.7858 2.02 68711 17451 2 1774.784193 888.4002 Nuclear pore complex protein Nup153 OS=Homo sapiens OX=9606 GN=NUP153 PE=1 SV=2 5.86 2988 - 812736 - - - -0.9077 - 2.874 0.721 - 731.3 1 2 0 -0.0016 15 0 0 0 5.02E+07 2.48E+07 - - - 6.9613 0.9995 221125_WJC_METTL3_EV_vs_WT_F05.17453.17453.3 1.14E-07 21/72 R.EGRPSGEAFVELESEDEVK.L "sp|P31943|HNRH1_HUMAN,tr|E7EQJ0|E7EQJ0_HUMAN,tr|D6RIH9|D6RIH9_HUMAN,tr|D6RJ04|D6RJ04_HUMAN,tr|D6RFM3|D6RFM3_HUMAN,tr|E9PCY7|E9PCY7_HUMAN,tr|D6RIT2|D6RIT2_HUMAN,tr|D6R9T0|D6R9T0_HUMAN,tr|D6RIU0|D6RIU0_HUMAN,tr|D6RAM1|D6RAM1_HUMAN,tr|D6RBM0|D6RBM0_HUMAN,tr|G8JLB6|G8JLB6_HUMAN,tr|D6RDL0|D6RDL0_HUMAN,tr|D6RDU3|D6RDU3_HUMAN,tr|E7EN40|E7EN40_HUMAN" 15 2105.9753 1.31 68712 17453 3 2105.962418 702.999 Heterogeneous nuclear ribonucleoprotein H OS=Homo sapiens OX=9606 GN=HNRNPH1 PE=1 SV=4 4.06 2988.2 - 6.83E+06 - - - -6.1212 - 3.288 0.545 - 510.5 1 2 0 -0.0129 19 0 0 0 1.47E+09 1.12E+09 - - - 7.5369 0.9966 221125_WJC_METTL3_EV_vs_WT_F05.17454.17454.3 6.30E-08 Dec-56 R.ATC[160.03]NNYTPQFQLRPS.Y sp|Q5T749|KPRP_HUMAN 1 1795.8312 3.61 68713 17454 3 1795.826518 599.6177 Keratinocyte proline-rich protein OS=Homo sapiens OX=9606 GN=KPRP PE=1 SV=1 8.27 2988.4 - 624701 - - - -2.5893 - 2.259 0.654 - 231 1 1 0 -0.0046 15 0 0 0 1.89E+07 5.24E+06 - - - 7.9566 0.9624 221125_WJC_METTL3_EV_vs_WT_F05.17456.17456.2 0.000142 14-Sep L.PLVDTHSK[136.11].R sp|P08670|VIME_HUMAN 1 903.4905 1.79 68715 17456 2 903.48793 452.7525 Vimentin OS=Homo sapiens OX=9606 GN=VIM PE=1 SV=4 7.17 2988.6 - 393620 - - - -2.8788 - 1.863 0.473 - 216 1 1 0 -0.0026 8 0 0 0 4.06E+07 2.26E+07 - - - 4.4103 0.9996 221125_WJC_METTL3_EV_vs_WT_F05.17459.17459.2 1.36E-05 28-Nov R.ETNLDSLPLVDTHSK[136.11].R sp|P08670|VIME_HUMAN 1 1675.8508 1.7 68716 17459 2 1675.846131 838.9327 Vimentin OS=Homo sapiens OX=9606 GN=VIM PE=1 SV=4 4.54 2989 - 3.79E+06 - - - -2.8039 - 2.453 0.542 - 255.4 1 2 0 -0.0047 15 0 0 0 4.73E+08 2.77E+08 - - - 5.2488 1 221125_WJC_METTL3_EV_vs_WT_F05.17460.17460.3 8.74E-09 16/48 K.NC[160.03]LTNFHGMDLTR[166.11].D "sp|P61247|RS3A_HUMAN,tr|H0Y8L7|H0Y8L7_HUMAN,tr|D6RED7|D6RED7_HUMAN,tr|D6RAS7|D6RAS7_HUMAN,tr|D6RB09|D6RB09_HUMAN,tr|E9PFI5|E9PFI5_HUMAN,tr|D6RAT0|D6RAT0_HUMAN,tr|D6RG13|D6RG13_HUMAN" 8 1587.7162 0.82 68717 17460 3 1587.712868 530.246 40S ribosomal protein S3a OS=Homo sapiens OX=9606 GN=RPS3A PE=1 SV=2 6.74 2989.1 - 499193 - - - -2.0684 - 2.843 0.633 - 405.2 1 2 0 -0.0033 13 0 0 0 1.33E+07 1.63E+07 - - - 8.4293 1 221125_WJC_METTL3_EV_vs_WT_F05.17465.17465.3 7.60E-07 16/48 K.NC[160.03]LTNFHGMDLTR.D "sp|P61247|RS3A_HUMAN,tr|H0Y8L7|H0Y8L7_HUMAN,tr|D6RED7|D6RED7_HUMAN,tr|D6RAS7|D6RAS7_HUMAN,tr|D6RB09|D6RB09_HUMAN,tr|E9PFI5|E9PFI5_HUMAN,tr|D6RAT0|D6RAT0_HUMAN,tr|D6RG13|D6RG13_HUMAN" 8 1577.7079 0.82 68719 17465 3 1577.707353 526.9099 40S ribosomal protein S3a OS=Homo sapiens OX=9606 GN=RPS3A PE=1 SV=2 6.74 2989.9 - 780569 - - - -0.3353 - 3.055 0.584 - 484 1 2 0 -0.0005 13 0 0 0 1.33E+07 1.63E+07 - - - 8.0788 1 221125_WJC_METTL3_EV_vs_WT_F05.17467.17467.4 1.65E-08 18/102 R.TGMVIHQVEAKPSVYFIK.F "sp|Q5JUX0|SPIN3_HUMAN,sp|Q9Y657|SPIN1_HUMAN,tr|A0A1W2PR54|A0A1W2PR54_HUMAN" 3 2046.0972 2.6 68721 17467 4 2046.095325 512.5316 Spindlin-3 OS=Homo sapiens OX=9606 GN=SPIN3 PE=1 SV=1 8.2 2990.1 - 581074 - - - -0.9257 - 3.84 0.569 - 275 1 2 0 -0.0019 18 0 0 0 6.09E+07 2.35E+07 - - - 4.639 1 221125_WJC_METTL3_EV_vs_WT_F05.17473.17473.3 5.27E-13 22/72 R.EGR[166.11]PSGEAFVELESEDEVK[136.11].L "sp|P31943|HNRH1_HUMAN,tr|E7EQJ0|E7EQJ0_HUMAN,tr|D6RIH9|D6RIH9_HUMAN,tr|D6RJ04|D6RJ04_HUMAN,tr|D6RFM3|D6RFM3_HUMAN,tr|E9PCY7|E9PCY7_HUMAN,tr|D6RIT2|D6RIT2_HUMAN,tr|D6R9T0|D6R9T0_HUMAN,tr|D6RIU0|D6RIU0_HUMAN,tr|D6RAM1|D6RAM1_HUMAN,tr|D6RBM0|D6RBM0_HUMAN,tr|G8JLB6|G8JLB6_HUMAN,tr|D6RDL0|D6RDL0_HUMAN,tr|D6RDU3|D6RDU3_HUMAN,tr|E7EN40|E7EN40_HUMAN" 15 2123.9978 1.31 68725 17473 3 2123.994556 709.0065 Heterogeneous nuclear ribonucleoprotein H OS=Homo sapiens OX=9606 GN=HNRNPH1 PE=1 SV=4 4.06 2990.7 - 3.95E+06 - - - -1.5174 - 4.264 0.661 - 690.3 1 2 0 -0.0032 19 0 0 0 1.47E+09 1.12E+09 - - - 9.4715 1 221125_WJC_METTL3_EV_vs_WT_F05.17474.17474.3 7.00E-14 21/84 R.LC[160.03]QADPDLDSDK[136.11]DETGAYLIDR[166.11].D "sp|Q9NXV2|KCTD5_HUMAN,tr|H3BSS5|H3BSS5_HUMAN" 2 2527.1503 9.59 68726 17474 3 2527.145654 843.3907 BTB\POZ domain-containing protein KCTD5 OS=Homo sapiens OX=9606 GN=KCTD5 PE=1 SV=1 3.8 2990.8 - 911134 - - - -1.8515 - 3.993 0.699 - 439.5 1 2 1 -0.0047 22 0 0 0 1.07E+08 1.12E+07 - - - 9.6144 1 221125_WJC_METTL3_EV_vs_WT_F05.17476.17476.2 3.21E-11 15/28 R.ATC[160.03]NNYTPQFQLRPS.Y sp|Q5T749|KPRP_HUMAN 1 1795.8312 6.3 68728 17476 2 1795.831787 898.9229 Keratinocyte proline-rich protein OS=Homo sapiens OX=9606 GN=KPRP PE=1 SV=1 8.27 2991.1 - 717396 - - - 0.3447 - 3.089 0.66 - 516.8 1 1 0 0.0006 15 0 0 0 1.82E+07 2.89E+06 - - - 6.6884 0.9999 221125_WJC_METTL3_EV_vs_WT_F05.17477.17477.4 1.85E-05 17/102 R.TGMVIHQVEAK[136.11]PSVYFIK[136.11].F "sp|Q5JUX0|SPIN3_HUMAN,sp|Q9Y657|SPIN1_HUMAN,tr|A0A1W2PR54|A0A1W2PR54_HUMAN" 3 2062.1256 2.59 68729 17477 4 2062.12238 516.5387 Spindlin-3 OS=Homo sapiens OX=9606 GN=SPIN3 PE=1 SV=1 8.2 2991.2 - 598686 - - - -1.5707 - 2.602 0.476 - 65 1 2 0 -0.0032 18 0 0 0 6.07E+07 2.35E+07 - - - 3.6958 1 221125_WJC_METTL3_EV_vs_WT_F05.17486.17486.3 1.32E-10 19/68 R.TGMVIHQVEAKPSVYFIK.F "sp|Q5JUX0|SPIN3_HUMAN,sp|Q9Y657|SPIN1_HUMAN,tr|A0A1W2PR54|A0A1W2PR54_HUMAN" 3 2046.0972 3.52 68735 17486 3 2046.092618 683.0397 Spindlin-3 OS=Homo sapiens OX=9606 GN=SPIN3 PE=1 SV=1 8.2 2992.3 - 577871 - - - -2.2487 - 3.825 0.616 - 462.3 1 2 0 -0.0046 18 0 0 0 1.94E+07 5.50E+06 - - - 8.7471 1 221125_WJC_METTL3_EV_vs_WT_F05.17490.17490.3 1.80E-09 16/68 K.SKPGAAMVEMADGYAVDR.A "sp|P14866|HNRPL_HUMAN,tr|M0QYT0|M0QYT0_HUMAN,tr|A0A3B3ITJ4|A0A3B3ITJ4_HUMAN,tr|M0QXS5|M0QXS5_HUMAN" 4 1866.8604 0.89 68737 17490 3 1866.857183 623.2941 Heterogeneous nuclear ribonucleoprotein L OS=Homo sapiens OX=9606 GN=HNRNPL PE=1 SV=2 4.56 2992.8 - 1.27E+06 - - - -1.7334 - 3.194 0.609 - 355.1 1 2 0 -0.0032 18 0 0 0 1.51E+08 1.68E+08 - - - 8.2205 1 221125_WJC_METTL3_EV_vs_WT_F05.17497.17497.3 1.09E-07 16/64 R.EQSLDALQTHYDELQAR.L sp|Q08378|GOGA3_HUMAN 1 2015.9548 2.18 68742 17497 3 2015.951773 672.9922 Golgin subfamily A member 3 OS=Homo sapiens OX=9606 GN=GOLGA3 PE=1 SV=2 4.31 2993.7 - 1.04E+06 - - - -1.5253 - 3.437 0.562 - 442.6 1 2 0 -0.0031 17 0 0 0 1.87E+07 8.58E+06 - - - 7.9239 1 221125_WJC_METTL3_EV_vs_WT_F05.17505.17505.2 3.24E-07 18/36 R.EGR[166.11]PSGEAFVELESEDEVK[136.11].L "sp|P31943|HNRH1_HUMAN,tr|E7EQJ0|E7EQJ0_HUMAN,tr|D6RIH9|D6RIH9_HUMAN,tr|D6RJ04|D6RJ04_HUMAN,tr|D6RFM3|D6RFM3_HUMAN,tr|E9PCY7|E9PCY7_HUMAN,tr|D6RIT2|D6RIT2_HUMAN,tr|D6R9T0|D6R9T0_HUMAN,tr|D6RIU0|D6RIU0_HUMAN,tr|D6RAM1|D6RAM1_HUMAN,tr|D6RBM0|D6RBM0_HUMAN,tr|G8JLB6|G8JLB6_HUMAN,tr|D6RDL0|D6RDL0_HUMAN,tr|D6RDU3|D6RDU3_HUMAN,tr|E7EN40|E7EN40_HUMAN" 15 2123.9978 1.46 68746 17505 2 2123.996376 1063.0062 Heterogeneous nuclear ribonucleoprotein H OS=Homo sapiens OX=9606 GN=HNRNPH1 PE=1 SV=4 4.06 2994.7 - 627352 - - - -0.6605 - 3.615 0.675 - 521.6 1 2 0 -0.0014 19 0 0 0 3.95E+07 2.70E+07 - - - 7.1856 0.9997 221125_WJC_METTL3_EV_vs_WT_F05.17509.17509.3 0.129 Oct-40 K.DHWWSAVQPER.R "sp|P39880|CUX1_HUMAN,tr|A0A2R8Y852|A0A2R8Y852_HUMAN,tr|A0A2R8YDI1|A0A2R8YDI1_HUMAN" 3 1409.6476 1.4 68749 17509 3 1409.6447 470.8898 Homeobox protein cut-like 1 OS=Homo sapiens OX=9606 GN=CUX1 PE=1 SV=3 5.32 2995.1 - 1.13E+06 - - - -2.0906 - 2.352 0.355 - 192 1 2 0 -0.0029 11 0 0 0 3.94E+07 2.82E+07 - - - 4.9267 1 221125_WJC_METTL3_EV_vs_WT_F05.17515.17515.2 2.78E-09 14/32 K.DHTPSQELALTQSVGGD.S "sp|Q86U44|MTA70_HUMAN,tr|H0YFV6|H0YFV6_HUMAN" 2 1753.8119 - 68752 17515 2 1753.807095 877.9132 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 4.27 2995.9 - 866704 - - - -2.7238 - 2.908 0.662 - 720.9 1 1 0 -0.0048 17 0 0 0 - - - - - 6.5534 1 221125_WJC_METTL3_EV_vs_WT_F05.17516.17516.2 3.02E-12 21/36 R.EGRPSGEAFVELESEDEVK.L "sp|P31943|HNRH1_HUMAN,tr|E7EQJ0|E7EQJ0_HUMAN,tr|D6RIH9|D6RIH9_HUMAN,tr|D6RJ04|D6RJ04_HUMAN,tr|D6RFM3|D6RFM3_HUMAN,tr|E9PCY7|E9PCY7_HUMAN,tr|D6RIT2|D6RIT2_HUMAN,tr|D6R9T0|D6R9T0_HUMAN,tr|D6RIU0|D6RIU0_HUMAN,tr|D6RAM1|D6RAM1_HUMAN,tr|D6RBM0|D6RBM0_HUMAN,tr|G8JLB6|G8JLB6_HUMAN,tr|D6RDL0|D6RDL0_HUMAN,tr|D6RDU3|D6RDU3_HUMAN,tr|E7EN40|E7EN40_HUMAN" 15 2105.9753 1.46 68753 17516 2 2105.966084 1053.9949 Heterogeneous nuclear ribonucleoprotein H OS=Homo sapiens OX=9606 GN=HNRNPH1 PE=1 SV=4 4.06 2996 - 648484 - - - -4.3804 - 4.125 0.702 - 687.4 1 2 0 -0.0092 19 0 0 0 3.95E+07 2.70E+07 - - - 7.707 0.959 221125_WJC_METTL3_EV_vs_WT_F05.17522.17522.2 0.0838 14-Sep L.PLVDTHSK.R sp|P08670|VIME_HUMAN 1 895.4763 1.79 68757 17522 2 895.474822 448.7454 Vimentin OS=Homo sapiens OX=9606 GN=VIM PE=1 SV=4 7.17 2996.7 - 1.15E+06 - - - -1.6851 - 1.839 0.319 - 215.2 1 1 0 -0.0015 8 0 0 0 4.06E+07 2.26E+07 - - - 3.234 0.9999 221125_WJC_METTL3_EV_vs_WT_F05.17530.17530.4 4.56E-07 15/78 K.HWPFMVVNDAGR[166.11]PK[136.11].V "sp|P11142|HSP7C_HUMAN,tr|E9PQQ4|E9PQQ4_HUMAN,tr|E9PNE6|E9PNE6_HUMAN,tr|E9PKE3|E9PKE3_HUMAN,tr|E9PN89|E9PN89_HUMAN,tr|E9PLF4|E9PLF4_HUMAN,tr|E9PK54|E9PK54_HUMAN,tr|E9PN25|E9PN25_HUMAN,tr|E9PPY6|E9PPY6_HUMAN,tr|E9PQK7|E9PQK7_HUMAN" 10 1670.847 0.13 68760 17530 4 1670.844152 418.719 Heat shock cognate 71 kDa protein OS=Homo sapiens OX=9606 GN=HSPA8 PE=1 SV=1 8.75 2997.7 - 975478 - - - -1.7261 - 2.541 0.478 - 228.3 1 2 0 -0.0029 14 0 0 0 2.94E+07 2.20E+08 - - - 3.7251 0.9995 221125_WJC_METTL3_EV_vs_WT_F05.17531.17531.3 5.57E-05 13/60 K.NLEQYNK[136.11]LDQDLNEVK[136.11].A sp|Q9UQE7|SMC3_HUMAN 1 1977.9978 0.82 68761 17531 3 1977.998332 660.3399 Structural maintenance of chromosomes protein 3 OS=Homo sapiens OX=9606 GN=SMC3 PE=1 SV=2 4.32 2997.9 - 1.19E+06 - - - 0.2513 - 2.766 0.352 - 120.6 1 2 1 0.0005 16 0 0 0 4.00E+07 4.89E+07 - - - 5.0748 1 221125_WJC_METTL3_EV_vs_WT_F05.17535.17535.3 1.08E-05 13/68 K.SK[136.11]PGAAMVEMADGYAVDR[166.11].A "sp|P14866|HNRPL_HUMAN,tr|M0QYT0|M0QYT0_HUMAN,tr|A0A3B3ITJ4|A0A3B3ITJ4_HUMAN,tr|M0QXS5|M0QXS5_HUMAN" 4 1884.8829 0.82 68764 17535 3 1884.878907 629.3016 Heterogeneous nuclear ribonucleoprotein L OS=Homo sapiens OX=9606 GN=HNRNPL PE=1 SV=2 4.56 2998.3 - 6.88E+06 - - - -2.1126 - 3.016 0.534 - 242.5 1 2 0 -0.004 18 0 0 0 1.51E+08 1.83E+08 - - - 7.2414 0.9999 221125_WJC_METTL3_EV_vs_WT_F05.17538.17538.3 8.32E-10 17/60 K.NLEQYNKLDQDLNEVK.A sp|Q9UQE7|SMC3_HUMAN 1 1961.9694 0.82 68766 17538 3 1961.96674 654.9971 Structural maintenance of chromosomes protein 3 OS=Homo sapiens OX=9606 GN=SMC3 PE=1 SV=2 4.32 2998.7 - 1.63E+06 - - - -1.3736 - 3.802 0.574 - 270.9 1 2 1 -0.0027 16 0 0 0 4.00E+07 4.89E+07 - - - 8.3656 0.9999 221125_WJC_METTL3_EV_vs_WT_F05.17539.17539.3 0.0806 13/60 R.IWTEDGNLASTLGQHK.G "sp|O60907|TBL1X_HUMAN,tr|A0A804HJZ5|A0A804HJZ5_HUMAN,tr|A0A2R8YFW3|A0A2R8YFW3_HUMAN" 3 1768.8744 3.58 68767 17539 3 1768.875467 590.6321 F-box-like\WD repeat-containing protein TBL1X OS=Homo sapiens OX=9606 GN=TBL1X PE=1 SV=3 5.32 2998.8 - 1.17E+06 - - - 0.5959 - 2.63 0.379 - 190 1 2 0 0.0011 16 0 0 0 2.82E+07 7.89E+06 - - - 5.2463 1 221125_WJC_METTL3_EV_vs_WT_F05.17540.17540.3 6.14E-08 14/52 K.SGEEGMPDLAHVMR.L "sp|O75688|PPM1B_HUMAN,tr|B8ZZF0|B8ZZF0_HUMAN,tr|A0A3B3IS24|A0A3B3IS24_HUMAN,tr|C9JIR6|C9JIR6_HUMAN" 4 1527.681 3.48 68768 17540 3 1527.679325 510.2343 Protein phosphatase 1B OS=Homo sapiens OX=9606 GN=PPM1B PE=1 SV=1 4.65 2998.9 - 697928 - - - -1.0951 - 2.165 0.624 - 131.9 1 2 0 -0.0017 14 0 0 0 2.85E+08 8.20E+07 - - - 7.5492 0.9993 221125_WJC_METTL3_EV_vs_WT_F05.17549.17549.4 0.00278 13/78 R.EDLHILFSNHGEIK.W sp|P05455|LA_HUMAN 1 1650.8366 0.97 68775 17549 4 1650.833164 413.7164 Lupus La protein OS=Homo sapiens OX=9606 GN=SSB PE=1 SV=2 5.28 3000 - 964369 - - - -2.0632 - 2.154 0.331 - 105.5 1 2 0 -0.0034 14 0 0 0 1.66E+07 1.70E+07 - - - 2.3853 0.9997 221125_WJC_METTL3_EV_vs_WT_F05.17554.17554.3 0.0129 14/60 R.SK[136.11]FDELSASNLPPNLK[136.11].L sp|Q8N5N7|RM50_HUMAN 1 1774.9436 2.33 68778 17554 3 1774.942447 592.6551 "39S ribosomal protein L50, mitochondrial OS=Homo sapiens OX=9606 GN=MRPL50 PE=1 SV=2" 5.79 3000.7 - 822885 - - - -0.658 - 2.593 0.42 - 174.1 1 2 1 -0.0012 16 0 0 0 8.41E+07 3.61E+07 - - - 5.6671 1 221125_WJC_METTL3_EV_vs_WT_F05.17558.17558.3 2.36E-10 16/68 K.NLTVILSDASAPGEGEHK[136.11].L sp|Q9H0D6|XRN2_HUMAN 1 1844.936 0.96 68780 17558 3 1844.930826 615.9859 5'-3' exoribonuclease 2 OS=Homo sapiens OX=9606 GN=XRN2 PE=1 SV=1 4.65 3001.2 - 6.22E+06 - - - -2.7811 - 3.056 0.636 - 257.2 1 2 0 -0.0051 18 0 0 0 5.05E+08 5.29E+08 - - - 8.4111 0.9972 221125_WJC_METTL3_EV_vs_WT_F05.17561.17561.3 0.00954 Oct-40 K.TKENILEEFSK.V "sp|O43390|HNRPR_HUMAN,tr|B4DT28|B4DT28_HUMAN,tr|A0A6Q8PHG0|A0A6Q8PHG0_HUMAN,tr|A0A6Q8PH31|A0A6Q8PH31_HUMAN,tr|A0A6Q8PEX7|A0A6Q8PEX7_HUMAN" 5 1336.6874 1.35 68783 17561 3 1336.684349 446.5698 Heterogeneous nuclear ribonucleoprotein R OS=Homo sapiens OX=9606 GN=HNRNPR PE=1 SV=1 4.78 3001.5 - 784243 - - - -2.3177 - 2.049 0.334 - 208.7 1 2 1 -0.0031 11 0 0 0 2.66E+08 1.98E+08 - - - 4.3008 0.9968 221125_WJC_METTL3_EV_vs_WT_F05.17569.17569.3 0.0272 13/64 K.ADDKLIAEEGVDSLNVK.E sp|O95202|LETM1_HUMAN 1 1814.9262 0.61 68789 17569 3 1814.929003 605.9827 Mitochondrial proton\calcium exchanger protein OS=Homo sapiens OX=9606 GN=LETM1 PE=1 SV=1 4.11 3002.5 - 1.31E+06 - - - 1.5593 - 2.4 0.28 - 169.1 1 2 1 0.0028 17 0 0 0 1.18E+07 1.95E+07 - - - 3.8726 0.9996 221125_WJC_METTL3_EV_vs_WT_F05.17574.17574.3 0.000525 Dec-40 K.TK[136.11]ENILEEFSK[136.11].V "sp|O43390|HNRPR_HUMAN,tr|B4DT28|B4DT28_HUMAN,tr|A0A6Q8PHG0|A0A6Q8PHG0_HUMAN,tr|A0A6Q8PH31|A0A6Q8PH31_HUMAN,tr|A0A6Q8PEX7|A0A6Q8PEX7_HUMAN" 5 1352.7158 1.35 68792 17574 3 1352.713182 451.9126 Heterogeneous nuclear ribonucleoprotein R OS=Homo sapiens OX=9606 GN=HNRNPR PE=1 SV=1 4.78 3003 - 2.17E+06 - - - -1.9701 - 2.37 0.449 - 344.4 1 2 1 -0.0027 11 0 0 0 2.66E+08 1.98E+08 - - - 5.9965 1 221125_WJC_METTL3_EV_vs_WT_F05.17575.17575.2 2.93E-08 16/34 K.NLTVILSDASAPGEGEHK[136.11].L sp|Q9H0D6|XRN2_HUMAN 1 1844.936 0.45 68793 17575 2 1844.937407 923.4753 5'-3' exoribonuclease 2 OS=Homo sapiens OX=9606 GN=XRN2 PE=1 SV=1 4.65 3003.2 - 536662 - - - 0.7859 - 3.016 0.672 - 711.4 1 2 0 0.0014 18 0 0 0 1.23E+07 2.73E+07 - - - 6.718 1 221125_WJC_METTL3_EV_vs_WT_F05.17587.17587.3 1.07E-09 14/52 K.SGEEGMPDLAHVMR[166.11].L "sp|O75688|PPM1B_HUMAN,tr|B8ZZF0|B8ZZF0_HUMAN,tr|A0A3B3IS24|A0A3B3IS24_HUMAN,tr|C9JIR6|C9JIR6_HUMAN" 4 1537.6893 3.49 68801 17587 3 1537.687179 513.5704 Protein phosphatase 1B OS=Homo sapiens OX=9606 GN=PPM1B PE=1 SV=1 4.65 3004.6 - 768213 - - - -1.3585 - 2.694 0.615 - 379.3 1 2 0 -0.0021 14 0 0 0 2.85E+08 8.18E+07 - - - 8.0297 1 221125_WJC_METTL3_EV_vs_WT_F05.17593.17593.2 0.000373 14/20 K.TKENILEEFSK.V "sp|O43390|HNRPR_HUMAN,tr|B4DT28|B4DT28_HUMAN,tr|A0A6Q8PHG0|A0A6Q8PHG0_HUMAN,tr|A0A6Q8PH31|A0A6Q8PH31_HUMAN,tr|A0A6Q8PEX7|A0A6Q8PEX7_HUMAN" 5 1336.6874 1.55 68805 17593 2 1336.684886 669.351 Heterogeneous nuclear ribonucleoprotein R OS=Homo sapiens OX=9606 GN=HNRNPR PE=1 SV=1 4.78 3005.3 - 1.37E+06 - - - -1.9159 - 2.897 0.544 - 522.5 1 2 1 -0.0026 11 0 0 0 7.29E+07 4.70E+07 - - - 5.9357 1 221125_WJC_METTL3_EV_vs_WT_F05.17602.17602.3 1.41E-10 14/52 K.HWPFMVVNDAGR[166.11]PK[136.11].V "sp|P11142|HSP7C_HUMAN,tr|E9PQQ4|E9PQQ4_HUMAN,tr|E9PNE6|E9PNE6_HUMAN,tr|E9PKE3|E9PKE3_HUMAN,tr|E9PN89|E9PN89_HUMAN,tr|E9PLF4|E9PLF4_HUMAN,tr|E9PK54|E9PK54_HUMAN,tr|E9PN25|E9PN25_HUMAN,tr|E9PPY6|E9PPY6_HUMAN,tr|E9PQK7|E9PQK7_HUMAN" 10 1670.847 0.12 68811 17602 3 1670.843855 557.9563 Heat shock cognate 71 kDa protein OS=Homo sapiens OX=9606 GN=HSPA8 PE=1 SV=1 8.75 3006.4 - 1.19E+07 - - - -1.9038 - 2.792 0.658 - 298.4 1 2 0 -0.0032 14 0 0 0 7.43E+07 6.19E+08 - - - 8.6038 0.9998 221125_WJC_METTL3_EV_vs_WT_F05.17611.17611.3 0.000114 Oct-44 R.DIKPDNLLLDSK.G sp|Q15208|STK38_HUMAN 1 1369.7453 4.74 68816 17611 3 1369.74168 457.589 Serine\threonine-protein kinase 38 OS=Homo sapiens OX=9606 GN=STK38 PE=1 SV=1 4.43 3007.4 - 1.84E+06 - - - -2.6399 - 2.208 0.417 - 148.5 1 2 0 -0.0036 12 0 0 0 3.69E+07 7.79E+06 - - - 5.3837 0.9796 221125_WJC_METTL3_EV_vs_WT_F05.17614.17614.2 0.00263 14-Aug V.VNDAGR[166.11]PK[136.11].V "sp|P11142|HSP7C_HUMAN,tr|E9PQQ4|E9PQQ4_HUMAN,tr|E9PNE6|E9PNE6_HUMAN,tr|E9PKE3|E9PKE3_HUMAN,tr|E9PN89|E9PN89_HUMAN,tr|E9PLF4|E9PLF4_HUMAN,tr|E9PK54|E9PK54_HUMAN,tr|E9PN25|E9PN25_HUMAN,tr|E9PPY6|E9PPY6_HUMAN,tr|E9PQK7|E9PQK7_HUMAN" 10 873.4787 0.03 68818 17614 2 873.477761 437.7466 Heat shock cognate 71 kDa protein OS=Homo sapiens OX=9606 GN=HSPA8 PE=1 SV=1 8.72 3007.8 - 229170 - - - -1.1151 - 1.557 0.447 - 168.2 1 1 0 -0.001 8 0 0 0 3.74E+05 1.17E+07 - - - 3.6776 1 221125_WJC_METTL3_EV_vs_WT_F05.17619.17619.2 1.30E-11 14/28 R.NQYDNDVTVWSPQGR[166.11].L "sp|P25786|PSA1_HUMAN,tr|B4DEV8|B4DEV8_HUMAN" 2 1787.8102 0.65 68819 17619 2 1787.805792 894.9124 Proteasome subunit alpha type-1 OS=Homo sapiens OX=9606 GN=PSMA1 PE=1 SV=1 4.21 3008.5 - 820217 - - - -2.4913 - 2.924 0.615 - 763 1 2 0 -0.0045 15 0 0 0 2.31E+07 3.55E+07 - - - 6.2199 0.9978 221125_WJC_METTL3_EV_vs_WT_F05.17621.17621.2 0.000542 15/20 K.TK[136.11]ENILEEFSK[136.11].V "sp|O43390|HNRPR_HUMAN,tr|B4DT28|B4DT28_HUMAN,tr|A0A6Q8PHG0|A0A6Q8PHG0_HUMAN,tr|A0A6Q8PH31|A0A6Q8PH31_HUMAN,tr|A0A6Q8PEX7|A0A6Q8PEX7_HUMAN" 5 1352.7158 1.55 68820 17621 2 1352.71387 677.3652 Heterogeneous nuclear ribonucleoprotein R OS=Homo sapiens OX=9606 GN=HNRNPR PE=1 SV=1 4.78 3008.7 - 2.17E+06 - - - -1.4615 - 2.238 0.479 - 651.9 1 2 1 -0.002 11 0 0 0 7.29E+07 4.70E+07 - - - 4.7576 1 221125_WJC_METTL3_EV_vs_WT_F05.17622.17622.3 1.33E-09 18/64 K.MVSDINNGWQHLEQAEK.G "sp|O43707|ACTN4_HUMAN,tr|F5GXS2|F5GXS2_HUMAN,tr|H7C144|H7C144_HUMAN" 3 1997.9265 1.92 68821 17622 3 1997.92934 666.9828 Alpha-actinin-4 OS=Homo sapiens OX=9606 GN=ACTN4 PE=1 SV=2 4.65 3008.9 - 1.54E+06 - - - 1.409 - 3.123 0.653 - 244.2 1 2 0 0.0028 17 0 0 0 2.39E+07 1.24E+07 - - - 8.6965 0.9999 221125_WJC_METTL3_EV_vs_WT_F05.17626.17626.3 4.42E-06 17/52 R.TEISDK[136.11]ITSELVSK[136.11].L sp|Q14008|CKAP5_HUMAN 1 1564.8531 1.12 68825 17626 3 1564.850329 522.625 Cytoskeleton-associated protein 5 OS=Homo sapiens OX=9606 GN=CKAP5 PE=1 SV=3 4.68 3009.4 - 757520 - - - -1.7503 - 2.94 0.505 - 347.5 1 2 1 -0.0027 14 0 0 0 1.25E+07 1.12E+07 - - - 7.0354 0.9998 221125_WJC_METTL3_EV_vs_WT_F05.17631.17631.3 2.81E-07 23/76 R.SPWSNK[136.11]YDPPLEDGAMPSAR[166.11].L "sp|P47756|CAPZB_HUMAN,tr|B1AK87|B1AK87_HUMAN,tr|B1AK88|B1AK88_HUMAN,tr|A0A6I8PRV6|A0A6I8PRV6_HUMAN,tr|B1AK85|B1AK85_HUMAN" 5 2235.0385 0.5 68828 17631 3 2235.030552 746.0201 F-actin-capping protein subunit beta OS=Homo sapiens OX=9606 GN=CAPZB PE=1 SV=4 4.56 3009.9 - 1.08E+06 - - - -3.5731 - 4.022 0.587 - 753.7 1 2 1 -0.008 20 0 0 0 2.65E+07 5.35E+07 - - - 8.4587 0.9999 221125_WJC_METTL3_EV_vs_WT_F05.17632.17632.3 3.13E-06 21/64 R.AALEEVYPDLTPEETRR.N sp|Q9H0D6|XRN2_HUMAN 1 1987.9851 1.4 68829 17632 3 1987.979269 663.669 5'-3' exoribonuclease 2 OS=Homo sapiens OX=9606 GN=XRN2 PE=1 SV=1 4.25 3010 - 1.08E+06 - - - -2.9256 - 2.898 0.48 - 589.2 1 2 0 -0.0058 17 0 0 0 3.44E+07 2.46E+07 - - - 6.578 0.9999 221125_WJC_METTL3_EV_vs_WT_F05.17637.17637.2 1.25E-07 16/28 R.GALQNIIPASTGAAK.A "sp|P04406|G3P_HUMAN,tr|E7EUT5|E7EUT5_HUMAN" 2 1410.7831 1.1 68832 17637 2 1410.783461 706.3988 Glyceraldehyde-3-phosphate dehydrogenase OS=Homo sapiens OX=9606 GN=GAPDH PE=1 SV=3 8.75 3010.7 - 1.29E+06 - - - 0.2715 - 2.654 0.534 - 653.3 1 2 0 0.0004 15 0 0 0 1.55E+08 1.41E+08 - - - 5.3847 1 221125_WJC_METTL3_EV_vs_WT_F05.17638.17638.2 3.90E-10 14/28 R.NQYDNDVTVWSPQGR.L "sp|P25786|PSA1_HUMAN,tr|B4DEV8|B4DEV8_HUMAN" 2 1777.802 0.65 68833 17638 2 1777.798298 889.9083 Proteasome subunit alpha type-1 OS=Homo sapiens OX=9606 GN=PSMA1 PE=1 SV=1 4.21 3010.8 - 869409 - - - -2.0688 - 2.734 0.677 - 708.6 1 2 0 -0.0037 15 0 0 0 2.31E+07 3.55E+07 - - - 6.5129 0.9992 221125_WJC_METTL3_EV_vs_WT_F05.17641.17641.2 8.81E-05 22-Oct R.DIKPDNLLLDSK.G sp|Q15208|STK38_HUMAN 1 1369.7453 28.6 68834 17641 2 1369.741227 685.8799 Serine\threonine-protein kinase 38 OS=Homo sapiens OX=9606 GN=STK38 PE=1 SV=1 4.43 3011.2 - 361926 - - - -2.9706 - 1.794 0.494 - 159.6 1 2 0 -0.0041 12 0 0 0 9.67E+06 3.38E+05 - - - 4.2262 0.9817 221125_WJC_METTL3_EV_vs_WT_F05.17644.17644.2 0.000577 16-Oct M.VVNDAGR[166.11]PK[136.11].V "sp|P11142|HSP7C_HUMAN,tr|E9PQQ4|E9PQQ4_HUMAN,tr|E9PNE6|E9PNE6_HUMAN,tr|E9PKE3|E9PKE3_HUMAN,tr|E9PN89|E9PN89_HUMAN,tr|E9PLF4|E9PLF4_HUMAN,tr|E9PK54|E9PK54_HUMAN,tr|E9PN25|E9PN25_HUMAN,tr|E9PPY6|E9PPY6_HUMAN,tr|E9PQK7|E9PQK7_HUMAN" 10 972.5471 0.14 68837 17644 2 972.546212 487.2809 Heat shock cognate 71 kDa protein OS=Homo sapiens OX=9606 GN=HSPA8 PE=1 SV=1 8.72 3011.6 - 508281 - - - -0.9634 - 1.893 0.385 - 308 1 1 0 -0.0009 9 0 0 0 5.97E+06 4.19E+07 - - - 3.7306 0.9998 221125_WJC_METTL3_EV_vs_WT_F05.17647.17647.2 9.40E-05 13/28 R.GALQNIIPASTGAAK[136.11].A "sp|P04406|G3P_HUMAN,tr|E7EUT5|E7EUT5_HUMAN" 2 1418.7973 1.1 68838 17647 2 1418.794937 710.4059 Glyceraldehyde-3-phosphate dehydrogenase OS=Homo sapiens OX=9606 GN=GAPDH PE=1 SV=3 8.75 3012 - 1.34E+06 - - - -1.65 - 2.692 0.429 - 382.5 1 2 0 -0.0023 15 0 0 0 1.55E+08 1.41E+08 - - - 4.6435 0.9999 221125_WJC_METTL3_EV_vs_WT_F05.17648.17648.3 6.90E-05 17/56 K.QNLSELEQLNENLK[136.11]K[136.11].V "sp|Q15643|TRIPB_HUMAN,tr|H0YJ97|H0YJ97_HUMAN" 2 1814.9709 1.31 68839 17648 3 1814.966229 605.9976 Thyroid receptor-interacting protein 11 OS=Homo sapiens OX=9606 GN=TRIP11 PE=1 SV=3 4.79 3012.1 - 978665 - - - -2.5692 - 3.011 0.439 - 351.6 1 2 0 -0.0047 15 0 0 0 1.34E+08 1.03E+08 - - - 6.3094 0.9623 221125_WJC_METTL3_EV_vs_WT_F05.17649.17649.3 0.000343 Dec-56 K.EDK[136.11]LEC[160.03]SEELGDLVK[136.11].S "sp|Q00610|CLH1_HUMAN,sp|P53675|CLH2_HUMAN,tr|A0A087WVQ6|A0A087WVQ6_HUMAN,tr|A0A087WX41|A0A087WX41_HUMAN" 4 1778.8579 2.19 68840 17649 3 1778.869216 593.9599 Clathrin heavy chain 1 OS=Homo sapiens OX=9606 GN=CLTC PE=1 SV=5 4.08 3012.3 - 587695 - - - 6.3636 - 2.004 0.375 - 159 1 2 1 0.0113 15 0 0 0 1.62E+07 7.42E+06 - - - 4.5316 0.9997 221125_WJC_METTL3_EV_vs_WT_F05.17650.17650.4 2.87E-05 20/90 R.YSPEFK[136.11]DPLIDK[136.11]EYYR[166.11].K "sp|Q9Y2R9|RT07_HUMAN,tr|J3QKW2|J3QKW2_HUMAN,tr|J3QLS3|J3QLS3_HUMAN" 3 2088.0414 1.01 68841 17650 4 2088.037393 523.0176 "28S ribosomal protein S7, mitochondrial OS=Homo sapiens OX=9606 GN=MRPS7 PE=1 SV=2" 4.78 3012.4 - 489230 - - - -1.9324 - 3.677 0.449 - 405.6 1 2 2 -0.004 16 0 0 0 1.98E+07 1.96E+07 - - - 3.5917 1 221125_WJC_METTL3_EV_vs_WT_F05.17651.17651.2 1.16E-10 13/32 K.NASTFEDVTQVSSAYQK[136.11].T sp|Q14247|SRC8_HUMAN 1 1881.8836 0.42 68842 17651 2 1881.88264 941.9491 Src substrate cortactin OS=Homo sapiens OX=9606 GN=CTTN PE=1 SV=2 4.37 3012.5 - 335027 - - - -0.5032 - 2.832 0.715 - 541.1 1 2 0 -0.0009 17 0 0 0 2.77E+06 6.60E+06 - - - 6.881 0.9994 221125_WJC_METTL3_EV_vs_WT_F05.17653.17653.3 0.0396 Dec-60 R.SKFDELSASNLPPNLK.L sp|Q8N5N7|RM50_HUMAN 1 1758.9152 2.49 68843 17653 3 1758.914764 587.3123 "39S ribosomal protein L50, mitochondrial OS=Homo sapiens OX=9606 GN=MRPL50 PE=1 SV=2" 5.79 3012.7 - 676367 - - - -0.2564 - 2.502 0.367 - 123.4 1 2 1 -0.0005 16 0 0 0 4.81E+07 1.93E+07 - - - 4.9847 0.9967 221125_WJC_METTL3_EV_vs_WT_F05.17655.17655.3 8.48E-06 Nov-56 K.EDKLEC[160.03]SEELGDLVK.S "sp|Q00610|CLH1_HUMAN,sp|P53675|CLH2_HUMAN,tr|A0A087WVQ6|A0A087WVQ6_HUMAN,tr|A0A087WX41|A0A087WX41_HUMAN" 4 1762.8295 2.34 68844 17655 3 1762.829062 588.6171 Clathrin heavy chain 1 OS=Homo sapiens OX=9606 GN=CLTC PE=1 SV=5 4.08 3013 - 983055 - - - -0.2462 - 2.048 0.282 - 147.4 1 2 1 -0.0004 15 0 0 0 1.73E+07 7.42E+06 - - - 3.5545 0.9999 221125_WJC_METTL3_EV_vs_WT_F05.17657.17657.3 4.86E-08 23/76 R.SPWSNKYDPPLEDGAMPSAR.L "sp|P47756|CAPZB_HUMAN,tr|B1AK87|B1AK87_HUMAN,tr|B1AK88|B1AK88_HUMAN,tr|A0A6I8PRV6|A0A6I8PRV6_HUMAN,tr|B1AK85|B1AK85_HUMAN" 5 2217.0161 0.5 68846 17657 3 2217.01159 740.0126 F-actin-capping protein subunit beta OS=Homo sapiens OX=9606 GN=CAPZB PE=1 SV=4 4.56 3013.2 - 1.04E+06 - - - -2.0198 - 3.868 0.494 - 771.8 1 2 1 -0.0045 20 0 0 0 2.65E+07 5.32E+07 - - - 7.3281 0.9999 221125_WJC_METTL3_EV_vs_WT_F05.17659.17659.4 2.04E-07 22/90 R.YSPEFKDPLIDKEYYR.K "sp|Q9Y2R9|RT07_HUMAN,tr|J3QKW2|J3QKW2_HUMAN,tr|J3QLS3|J3QLS3_HUMAN" 3 2062.0048 1.01 68848 17659 4 2062.002823 516.5085 "28S ribosomal protein S7, mitochondrial OS=Homo sapiens OX=9606 GN=MRPS7 PE=1 SV=2" 4.78 3013.5 - 743906 - - - -0.9384 - 3.071 0.52 - 332.9 1 2 2 -0.0019 16 0 0 0 1.98E+07 1.96E+07 - - - 4.1468 1 221125_WJC_METTL3_EV_vs_WT_F05.17660.17660.3 2.57E-05 Nov-64 K.HPVTGQFLYQDSNWASK.V "sp|P02786|TFR1_HUMAN,tr|G3V0E5|G3V0E5_HUMAN" 2 1976.9381 1.4 68849 17660 3 1976.94071 659.9866 Transferrin receptor protein 1 OS=Homo sapiens OX=9606 GN=TFRC PE=1 SV=2 6.74 3013.6 - 728765 - - - 1.3329 - 2.13 0.529 - 114 1 2 0 0.0026 17 0 0 0 1.36E+07 9.71E+06 - - - 6.3473 0.9989 221125_WJC_METTL3_EV_vs_WT_F05.17661.17661.3 0.00142 Oct-60 R.YSPEFK[136.11]DPLIDK[136.11]EYYR[166.11].K "sp|Q9Y2R9|RT07_HUMAN,tr|J3QKW2|J3QKW2_HUMAN,tr|J3QLS3|J3QLS3_HUMAN" 3 2088.0414 2.45 68850 17661 3 2088.039781 697.0211 "28S ribosomal protein S7, mitochondrial OS=Homo sapiens OX=9606 GN=MRPS7 PE=1 SV=2" 4.78 3013.7 - 398567 - - - -0.7888 - 1.99 0.369 - 122.6 1 2 2 -0.0016 16 0 0 0 1.31E+07 5.36E+06 - - - 4.4192 0.9998 221125_WJC_METTL3_EV_vs_WT_F05.17662.17662.3 0.00051 Nov-48 R.KSSSGLTYIAEWK.G sp|P33908|MA1A1_HUMAN 1 1468.7562 1.92 68851 17662 3 1468.755359 490.5927 "Mannosyl-oligosaccharide 1,2-alpha-mannosidase IA OS=Homo sapiens OX=9606 GN=MAN1A1 PE=1 SV=3" 8.5 3013.8 - 344691 - - - -0.5692 - 2.061 0.375 - 169.2 1 2 0 -0.0008 13 0 0 0 4.80E+06 2.50E+06 - - - 4.6814 1 221125_WJC_METTL3_EV_vs_WT_F05.17665.17665.3 9.16E-06 19/56 K.QNLSELEQLNENLKK.V "sp|Q15643|TRIPB_HUMAN,tr|H0YJ97|H0YJ97_HUMAN" 2 1798.9425 1.31 68852 17665 3 1798.94339 600.6548 Thyroid receptor-interacting protein 11 OS=Homo sapiens OX=9606 GN=TRIP11 PE=1 SV=3 4.79 3014.2 - 2.46E+06 - - - 0.4992 - 3.336 0.519 - 617.7 1 2 0 0.0009 15 0 0 0 1.34E+08 1.03E+08 - - - 7.4698 0.9999 221125_WJC_METTL3_EV_vs_WT_F05.17667.17667.3 6.27E-06 18/64 R.AALEEVYPDLTPEETR[166.11]R[166.11].N sp|Q9H0D6|XRN2_HUMAN 1 2008.0016 1.55 68854 17667 3 2008.004564 670.3412 5'-3' exoribonuclease 2 OS=Homo sapiens OX=9606 GN=XRN2 PE=1 SV=1 4.25 3014.5 - 919367 - - - 1.4636 - 3.17 0.428 - 397.3 1 2 0 0.0029 17 0 0 0 3.41E+07 2.20E+07 - - - 6.2256 1 221125_WJC_METTL3_EV_vs_WT_F05.17668.17668.3 9.87E-06 16/56 K.K[136.11]SDIDEIVLVGGSTR[166.11].L "sp|P11021|BIP_HUMAN,tr|A0A7P0TB36|A0A7P0TB36_HUMAN" 2 1605.8693 0.56 68855 17668 3 1605.869807 536.297 Endoplasmic reticulum chaperone BiP OS=Homo sapiens OX=9606 GN=HSPA5 PE=1 SV=2 4.56 3014.6 - 600055 - - - 0.3338 - 2.715 0.524 - 299.8 1 2 0 0.0005 15 0 0 0 1.14E+08 2.04E+08 - - - 6.9881 1 221125_WJC_METTL3_EV_vs_WT_F05.17673.17673.3 3.88E-10 16/76 R.FGGQGNQFSYIQSGC[160.03]QSGIK.G sp|Q5D862|FILA2_HUMAN 1 2161.9851 89.1 68858 17673 3 2161.981846 721.669 Filaggrin-2 OS=Homo sapiens OX=9606 GN=FLG2 PE=1 SV=1 8.2 3015.4 - 881699 - - - -1.506 - 3.412 0.61 - 266.1 1 2 0 -0.0033 20 0 0 0 1.29E+07 1.45E+05 - - - 8.3175 0.9999 221125_WJC_METTL3_EV_vs_WT_F05.17675.17675.4 1.05E-07 18/96 R.LVQAEYWHDPIKEDVYR.N "sp|P50897|PPT1_HUMAN,tr|Q5T0S4|Q5T0S4_HUMAN,tr|A0A2C9F2P4|A0A2C9F2P4_HUMAN,tr|E9PIA8|E9PIA8_HUMAN,tr|A0A286YFL8|A0A286YFL8_HUMAN,tr|A0A286YFF7|A0A286YFF7_HUMAN,tr|A0A286YFE3|A0A286YFE3_HUMAN" 7 2160.064 1.3 68860 17675 4 2160.061895 541.0233 Palmitoyl-protein thioesterase 1 OS=Homo sapiens OX=9606 GN=PPT1 PE=1 SV=1 4.75 3015.7 - 778578 - - - -0.9764 - 3.026 0.556 - 261.7 1 2 1 -0.0021 17 0 0 0 5.73E+06 4.41E+06 - - - 4.4493 0.9999 221125_WJC_METTL3_EV_vs_WT_F05.17676.17676.4 1.70E-05 17/102 R.AIQFLHQDSPSLIHGDIK.S "sp|P51617|IRAK1_HUMAN,tr|H7C224|H7C224_HUMAN,tr|D3YTB5|D3YTB5_HUMAN" 3 2018.0585 1.63 68861 17676 4 2018.057532 505.5219 Interleukin-1 receptor-associated kinase 1 OS=Homo sapiens OX=9606 GN=IRAK1 PE=1 SV=2 5.98 3015.8 - 739063 - - - -0.4921 - 2.784 0.436 - 167.1 1 2 0 -0.001 18 0 0 0 1.58E+07 9.66E+06 - - - 3.3714 1 221125_WJC_METTL3_EV_vs_WT_F05.17677.17677.2 1.44E-06 14/32 R.SQNIVTDSSSLSAEAIR.Q "sp|Q01082|SPTB2_HUMAN,tr|A0A087WUZ3|A0A087WUZ3_HUMAN" 2 1776.8854 1.56 68862 17677 2 1776.885775 889.45 "Spectrin beta chain, non-erythrocytic 1 OS=Homo sapiens OX=9606 GN=SPTBN1 PE=1 SV=2" 4.37 3015.9 - 693456 - - - 0.2274 - 2.562 0.596 - 526.9 1 2 0 0.0004 17 0 0 0 2.33E+07 1.50E+07 - - - 5.7559 0.9999 221125_WJC_METTL3_EV_vs_WT_F05.17678.17678.4 9.82E-05 16/102 R.AIQFLHQDSPSLIHGDIK[136.11].S "sp|P51617|IRAK1_HUMAN,tr|H7C224|H7C224_HUMAN,tr|D3YTB5|D3YTB5_HUMAN" 3 2026.0727 1.87 68863 17678 4 2026.074179 507.5255 Interleukin-1 receptor-associated kinase 1 OS=Homo sapiens OX=9606 GN=IRAK1 PE=1 SV=2 5.98 3016.1 - 651445 - - - 0.7176 - 2.293 0.403 - 111 1 2 0 0.0015 18 0 0 0 1.81E+07 9.66E+06 - - - 3.0176 1 221125_WJC_METTL3_EV_vs_WT_F05.17682.17682.3 5.65E-08 18/52 K.HWPFMVVNDAGRPK.V "sp|P11142|HSP7C_HUMAN,tr|E9PQQ4|E9PQQ4_HUMAN,tr|E9PNE6|E9PNE6_HUMAN,tr|E9PKE3|E9PKE3_HUMAN,tr|E9PN89|E9PN89_HUMAN,tr|E9PLF4|E9PLF4_HUMAN,tr|E9PK54|E9PK54_HUMAN,tr|E9PN25|E9PN25_HUMAN,tr|E9PPY6|E9PPY6_HUMAN,tr|E9PQK7|E9PQK7_HUMAN" 10 1652.8246 0.11 68866 17682 3 1652.826285 551.9488 Heat shock cognate 71 kDa protein OS=Homo sapiens OX=9606 GN=HSPA8 PE=1 SV=1 8.75 3016.5 - 3.09E+06 - - - 1.04 - 2.966 0.608 - 518.4 1 2 0 0.0017 14 0 0 0 8.15E+07 7.44E+08 - - - 8.2074 0.9997 221125_WJC_METTL3_EV_vs_WT_F05.17686.17686.4 1.21E-05 Nov-72 K.LKDLFDYSPPLHK.N "sp|Q9NYF8|BCLF1_HUMAN,tr|E9PKI6|E9PKI6_HUMAN,tr|A0A1W2PQ43|A0A1W2PQ43_HUMAN,tr|E9PK91|E9PK91_HUMAN,tr|E9PK09|E9PK09_HUMAN,tr|E9PQN2|E9PQN2_HUMAN" 6 1571.8348 2.32 68869 17686 4 1571.834172 393.966 Bcl-2-associated transcription factor 1 OS=Homo sapiens OX=9606 GN=BCLAF1 PE=1 SV=2 6.75 3017 - 355895 - - - -0.3868 - 1.996 0.436 - 97.4 1 2 1 -0.0006 13 0 0 0 1.89E+07 8.15E+06 - - - 3.277 1 221125_WJC_METTL3_EV_vs_WT_F05.17687.17687.3 5.55E-07 Dec-76 K.SFENSPGDLGNSSLPTAGYK.R "sp|P55197|AF10_HUMAN,tr|H0Y5P4|H0Y5P4_HUMAN" 2 2039.9436 4.96 68870 17687 3 2039.943468 680.9885 Protein AF-10 OS=Homo sapiens OX=9606 GN=MLLT10 PE=1 SV=2 4.37 3017.1 - 348694 - - - -0.0716 - 2.578 0.606 - 110.9 1 2 0 -0.0001 20 0 0 0 5.83E+06 1.18E+06 - - - 7.5937 1 221125_WJC_METTL3_EV_vs_WT_F05.17690.17690.2 1.09E-11 Dec-38 R.FGGQGNQFSYIQSGC[160.03]QSGIK.G sp|Q5D862|FILA2_HUMAN 1 2161.9851 999 68873 17690 2 2161.982871 1081.9998 Filaggrin-2 OS=Homo sapiens OX=9606 GN=FLG2 PE=1 SV=1 8.2 3017.5 - 210211 - - - -1.0319 - 3.068 0.723 - 396.9 1 2 0 -0.0022 20 0 0 0 2.63E+06 0.00E+00 - - - 7.1365 0.9999 221125_WJC_METTL3_EV_vs_WT_F05.17693.17693.3 4.74E-05 14/56 K.KSDIDEIVLVGGSTR.L "sp|P11021|BIP_HUMAN,tr|A0A7P0TB36|A0A7P0TB36_HUMAN" 2 1587.8468 0.56 68874 17693 3 1587.848848 530.2895 Endoplasmic reticulum chaperone BiP OS=Homo sapiens OX=9606 GN=HSPA5 PE=1 SV=2 4.56 3017.9 - 3.24E+06 - - - 1.2892 - 2.412 0.479 - 219.6 1 2 0 0.002 15 0 0 0 1.14E+08 2.04E+08 - - - 6.1772 1 221125_WJC_METTL3_EV_vs_WT_F05.17695.17695.3 2.11E-10 13/64 R.SQNIVTDSSSLSAEAIR.Q "sp|Q01082|SPTB2_HUMAN,tr|A0A087WUZ3|A0A087WUZ3_HUMAN" 2 1776.8854 1.36 68876 17695 3 1776.888585 593.3024 "Spectrin beta chain, non-erythrocytic 1 OS=Homo sapiens OX=9606 GN=SPTBN1 PE=1 SV=2" 4.37 3018.1 - 1.17E+06 - - - 1.8088 - 3.204 0.557 - 194.1 1 2 0 0.0032 17 0 0 0 1.25E+07 9.20E+06 - - - 7.6907 1 221125_WJC_METTL3_EV_vs_WT_F05.17696.17696.2 6.19E-06 16/32 R.SQNIVTDSSSLSAEAIR[166.11].Q "sp|Q01082|SPTB2_HUMAN,tr|A0A087WUZ3|A0A087WUZ3_HUMAN" 2 1786.8936 1.56 68877 17696 2 1786.896169 894.4541 "Spectrin beta chain, non-erythrocytic 1 OS=Homo sapiens OX=9606 GN=SPTBN1 PE=1 SV=2" 4.37 3018.2 - 985936 - - - 1.4147 - 2.792 0.633 - 730.9 1 2 0 0.0025 17 0 0 0 2.33E+07 1.50E+07 - - - 6.2399 1 221125_WJC_METTL3_EV_vs_WT_F05.17697.17697.2 1.30E-07 14/32 K.VVQNDAYTAPALPSSIR.T "sp|Q9BY77|PDIP3_HUMAN,tr|F6VRR5|F6VRR5_HUMAN,tr|F8WCX5|F8WCX5_HUMAN,tr|Q8WUT1|Q8WUT1_HUMAN" 4 1800.937 1.7 68878 17697 2 1800.936571 901.4758 Polymerase delta-interacting protein 3 OS=Homo sapiens OX=9606 GN=POLDIP3 PE=1 SV=2 5.81 3018.3 - 542236 - - - -0.2454 - 2.832 0.563 - 445.1 1 2 0 -0.0004 17 0 0 0 1.16E+07 6.85E+06 - - - 5.7585 0.9999 221125_WJC_METTL3_EV_vs_WT_F05.17699.17699.3 7.39E-05 Nov-44 K.SFQGEIDALSKR.S "sp|Q13948|CASP_HUMAN,sp|P39880|CUX1_HUMAN,tr|A0A2R8Y852|A0A2R8Y852_HUMAN,tr|A0A2R8YDI1|A0A2R8YDI1_HUMAN" 4 1349.6939 59.93 68880 17699 3 1349.693576 450.9053 Protein CASP OS=Homo sapiens OX=9606 GN=CUX1 PE=1 SV=2 5.79 3018.6 - 454422 - - - -0.2615 - 2.085 0.421 - 146.8 1 2 0 -0.0004 12 0 0 0 1.81E+08 3.02E+06 - - - 5.2703 0.9424 221125_WJC_METTL3_EV_vs_WT_F05.17700.17700.2 4.75 26-Jun K.HWPFMVVNDAGR[166.11]PK[136.11].V "sp|P11142|HSP7C_HUMAN,tr|E9PQQ4|E9PQQ4_HUMAN,tr|E9PNE6|E9PNE6_HUMAN,tr|E9PKE3|E9PKE3_HUMAN,tr|E9PN89|E9PN89_HUMAN,tr|E9PLF4|E9PLF4_HUMAN,tr|E9PK54|E9PK54_HUMAN,tr|E9PN25|E9PN25_HUMAN,tr|E9PPY6|E9PPY6_HUMAN,tr|E9PQK7|E9PQK7_HUMAN" 10 1670.847 0.02 68881 17700 2 1670.84457 836.4308 Heat shock cognate 71 kDa protein OS=Homo sapiens OX=9606 GN=HSPA8 PE=1 SV=1 8.75 3018.7 - 374913 - - - -1.4759 - 1.247 0.019 - 81.5 1 2 0 -0.0025 14 0 0 0 3.32E+05 1.37E+07 - - - -0.2655 1 221125_WJC_METTL3_EV_vs_WT_F05.17701.17701.2 4.17E-06 21/28 K.K[136.11]SDIDEIVLVGGSTR[166.11].L "sp|P11021|BIP_HUMAN,tr|A0A7P0TB36|A0A7P0TB36_HUMAN" 2 1605.8693 0.48 68882 17701 2 1605.874638 803.9419 Endoplasmic reticulum chaperone BiP OS=Homo sapiens OX=9606 GN=HSPA5 PE=1 SV=2 4.56 3018.8 - 368704 - - - 3.3421 - 4.101 0.564 - 1968.7 1 2 0 0.0054 15 0 0 0 6.83E+06 1.43E+07 - - - 6.6746 0.9998 221125_WJC_METTL3_EV_vs_WT_F05.17702.17702.2 0.000109 13/32 K.VVQNDAYTAPALPSSIR[166.11].T "sp|Q9BY77|PDIP3_HUMAN,tr|F6VRR5|F6VRR5_HUMAN,tr|F8WCX5|F8WCX5_HUMAN,tr|Q8WUT1|Q8WUT1_HUMAN" 4 1810.9453 1.7 68883 17702 2 1810.948695 906.4799 Polymerase delta-interacting protein 3 OS=Homo sapiens OX=9606 GN=POLDIP3 PE=1 SV=2 5.81 3019 - 350395 - - - 1.8841 - 2.427 0.567 - 402.9 1 2 0 0.0034 17 0 0 0 1.16E+07 6.85E+06 - - - 5.4077 0.9999 221125_WJC_METTL3_EV_vs_WT_F05.17706.17706.3 3.37E-06 15/72 R.EGRPSGEAFVELESEDEVK.L "sp|P31943|HNRH1_HUMAN,tr|E7EQJ0|E7EQJ0_HUMAN,tr|D6RIH9|D6RIH9_HUMAN,tr|D6RJ04|D6RJ04_HUMAN,tr|D6RFM3|D6RFM3_HUMAN,tr|E9PCY7|E9PCY7_HUMAN,tr|D6RIT2|D6RIT2_HUMAN,tr|D6R9T0|D6R9T0_HUMAN,tr|D6RIU0|D6RIU0_HUMAN,tr|D6RAM1|D6RAM1_HUMAN,tr|D6RBM0|D6RBM0_HUMAN,tr|G8JLB6|G8JLB6_HUMAN,tr|D6RDL0|D6RDL0_HUMAN,tr|D6RDU3|D6RDU3_HUMAN,tr|E7EN40|E7EN40_HUMAN" 15 2105.9753 1.31 68886 17706 3 2105.9813 702.999 Heterogeneous nuclear ribonucleoprotein H OS=Homo sapiens OX=9606 GN=HNRNPH1 PE=1 SV=4 4.06 3019.4 - 163068 - - - 2.8448 - 2.828 0.529 - 190 1 2 0 0.006 19 0 0 0 1.47E+09 1.12E+09 - - - 6.9902 0.9999 221125_WJC_METTL3_EV_vs_WT_F05.17710.17710.3 7.87E-07 13/52 R.VEVER[166.11]DNLAEDIMR[166.11].L "sp|P08670|VIME_HUMAN,tr|B0YJC4|B0YJC4_HUMAN" 2 1707.8365 1.49 68889 17710 3 1707.838271 570.2861 Vimentin OS=Homo sapiens OX=9606 GN=VIM PE=1 SV=4 4.18 3019.9 - 548581 - - - 1.0522 - 2.608 0.507 - 281.7 1 2 1 0.0018 14 0 0 0 1.70E+07 1.14E+07 - - - 6.7395 0.9942 221125_WJC_METTL3_EV_vs_WT_F05.17712.17712.3 0.271 Sep-68 R.AIQFLHQDSPSLIHGDIK[136.11].S "sp|P51617|IRAK1_HUMAN,tr|H7C224|H7C224_HUMAN,tr|D3YTB5|D3YTB5_HUMAN" 3 2026.0727 0.08 68891 17712 3 2026.069134 676.3649 Interleukin-1 receptor-associated kinase 1 OS=Homo sapiens OX=9606 GN=IRAK1 PE=1 SV=2 5.98 3020.2 - 392145 - - - -1.7724 - 1.394 0.273 - 32.1 1 2 0 -0.0036 18 0 0 0 3.32E+06 4.35E+07 - - - 2.4098 0.9988 221125_WJC_METTL3_EV_vs_WT_F05.17714.17714.3 0.0188 Oct-72 R.AIVPPYSLC[160.03]QTGEDLPK[136.11]DK[136.11].N sp|Q01804|OTUD4_HUMAN 1 2146.0951 1.66 68893 17714 3 2146.094882 716.3723 OTU domain-containing protein 4 OS=Homo sapiens OX=9606 GN=OTUD4 PE=1 SV=4 4.56 3020.4 - 193155 - - - -0.1048 - 1.857 0.383 - 55.2 1 2 1 -0.0002 19 0 0 0 4.71E+06 2.84E+06 - - - 4.3307 1 221125_WJC_METTL3_EV_vs_WT_F05.17720.17720.3 6.66E-09 18/68 K.SAVDYNTC[160.03]AGVWSQDKWK.G sp|Q9Y5A9|YTHD2_HUMAN 1 2113.9527 1.23 68897 17720 3 2113.954136 705.6582 YTH domain-containing family protein 2 OS=Homo sapiens OX=9606 GN=YTHDF2 PE=1 SV=2 5.68 3021.2 - 4.37E+06 - - - 0.6604 - 2.786 0.637 - 319.2 1 2 1 0.0014 18 0 0 0 5.01E+07 4.08E+07 - - - 8.1929 1 221125_WJC_METTL3_EV_vs_WT_F05.17721.17721.3 2.02E-06 15/52 R.DTGTEALTPHIWNR[166.11].L sp|P48634|PRC2A_HUMAN 1 1619.7931 1.23 68898 17721 3 1619.793648 540.9383 Protein PRRC2A OS=Homo sapiens OX=9606 GN=PRRC2A PE=1 SV=3 5.32 3021.3 - 591051 - - - 0.3142 - 2.824 0.423 - 339 1 2 0 0.0005 14 0 0 0 1.64E+07 1.34E+07 - - - 6.0148 0.9992 221125_WJC_METTL3_EV_vs_WT_F05.17723.17723.4 0.000266 14/66 K.LKDYAFIHFDER.D "sp|O60506|HNRPQ_HUMAN,tr|A0A7I2YQV8|A0A7I2YQV8_HUMAN,tr|A0A7I2YQN2|A0A7I2YQN2_HUMAN,tr|A0A7I2V4Z0|A0A7I2V4Z0_HUMAN,tr|B7Z645|B7Z645_HUMAN,tr|A0A7I2V2F2|A0A7I2V2F2_HUMAN,tr|A0A7I2V346|A0A7I2V346_HUMAN,tr|A0A7I2V309|A0A7I2V309_HUMAN" 8 1552.7674 1.17 68900 17723 4 1552.766748 389.1991 Heterogeneous nuclear ribonucleoprotein Q OS=Homo sapiens OX=9606 GN=SYNCRIP PE=1 SV=2 5.38 3021.6 - 468136 - - - -0.4379 - 2.379 0.375 - 226.1 1 2 1 -0.0007 12 0 0 0 1.89E+07 1.62E+07 - - - 2.8178 0.9949 221125_WJC_METTL3_EV_vs_WT_F05.17727.17727.3 6.41E-08 Nov-64 R.C[160.03]ASC[160.03]PYLGMPAFK[136.11]PGEK[136.11].V "sp|Q6FI81|CPIN1_HUMAN,tr|H3BV90|H3BV90_HUMAN" 2 1927.8965 1.39 68904 17727 3 1928.893073 643.6395 Anamorsin OS=Homo sapiens OX=9606 GN=CIAPIN1 PE=1 SV=2 8.03 3022.1 - 336886 - - - 516.8981 - 2.202 0.553 - 66 1 2 0 0.9965 17 0 0 0 7.92E+06 5.68E+06 - - - 6.4235 0.9818 221125_WJC_METTL3_EV_vs_WT_F05.17731.17731.2 1.05E-06 Nov-34 S.GGGFSASSLGGGFGGGSR.G sp|P35527|K1C9_HUMAN 1 1513.691 999 68908 17731 2 1513.694342 757.8528 "Keratin, type I cytoskeletal 9 OS=Homo sapiens OX=9606 GN=KRT9 PE=1 SV=3" 9.75 3022.6 - 154066 - - - 2.2283 - 1.962 0.576 - 152.6 1 1 0 0.0034 18 0 0 0 2.02E+06 0.00E+00 - - - 4.9512 0.9997 221125_WJC_METTL3_EV_vs_WT_F05.17737.17737.3 5.49E-07 16/44 K.LKDYAFIHFDER.D "sp|O60506|HNRPQ_HUMAN,tr|A0A7I2YQV8|A0A7I2YQV8_HUMAN,tr|A0A7I2YQN2|A0A7I2YQN2_HUMAN,tr|A0A7I2V4Z0|A0A7I2V4Z0_HUMAN,tr|B7Z645|B7Z645_HUMAN,tr|A0A7I2V2F2|A0A7I2V2F2_HUMAN,tr|A0A7I2V346|A0A7I2V346_HUMAN,tr|A0A7I2V309|A0A7I2V309_HUMAN" 8 1552.7674 2.21 68912 17737 3 1552.772294 518.5964 Heterogeneous nuclear ribonucleoprotein Q OS=Homo sapiens OX=9606 GN=SYNCRIP PE=1 SV=2 5.38 3023.4 - 1.09E+06 - - - 3.1338 - 2.718 0.537 - 354.2 1 2 1 0.0049 12 0 0 0 2.59E+07 1.17E+07 - - - 7.2972 0.9995 221125_WJC_METTL3_EV_vs_WT_F05.17739.17739.4 0.0384 15/66 K.LK[136.11]DYAFIHFDER[166.11].D "sp|O60506|HNRPQ_HUMAN,tr|A0A7I2YQV8|A0A7I2YQV8_HUMAN,tr|A0A7I2YQN2|A0A7I2YQN2_HUMAN,tr|A0A7I2V4Z0|A0A7I2V4Z0_HUMAN,tr|B7Z645|B7Z645_HUMAN,tr|A0A7I2V2F2|A0A7I2V2F2_HUMAN,tr|A0A7I2V346|A0A7I2V346_HUMAN,tr|A0A7I2V309|A0A7I2V309_HUMAN" 8 1570.7899 1.17 68914 17739 4 1570.789979 393.7048 Heterogeneous nuclear ribonucleoprotein Q OS=Homo sapiens OX=9606 GN=SYNCRIP PE=1 SV=2 5.38 3023.6 - 875531 - - - 0.0516 - 2.459 0.398 - 207.2 1 2 1 0.0001 12 0 0 0 1.90E+07 1.62E+07 - - - 3.0307 1 221125_WJC_METTL3_EV_vs_WT_F05.17740.17740.3 0.00134 21/76 R.ASLENVHPPIAPPPTEIPER[166.11].F "sp|Q75N03|HAKAI_HUMAN,tr|C9J2P9|C9J2P9_HUMAN" 2 2173.1407 0.72 68915 17740 3 2173.142162 725.3875 E3 ubiquitin-protein ligase Hakai OS=Homo sapiens OX=9606 GN=CBLL1 PE=1 SV=1 4.75 3023.7 - 834034 - - - 0.6783 - 3.257 0.489 - 438.8 1 2 0 0.0015 20 0 0 0 9.81E+06 1.36E+07 - - - 6.8561 0.9478 221125_WJC_METTL3_EV_vs_WT_F05.17749.17749.2 0.523 24-Apr K.LHC[160.03]LHFSSWDSSK.E sp|O75717|WDHD1_HUMAN 1 1602.7249 8.4 68922 17749 2 1602.726815 802.3697 WD repeat and HMG-box DNA-binding protein 1 OS=Homo sapiens OX=9606 GN=WDHD1 PE=1 SV=1 6.91 3024.8 - 1.46E+06 - - - 1.1874 - 0.999 0.135 - 32.7 4 2 0 0.0019 13 0 0 0 2.51E+07 2.99E+06 - - - -0.234 0.9998 221125_WJC_METTL3_EV_vs_WT_F05.17753.17753.3 6.16E-05 14/56 R.GALQNIIPASTGAAK.A "sp|P04406|G3P_HUMAN,tr|E7EUT5|E7EUT5_HUMAN" 2 1410.7831 0.52 68926 17753 3 1410.779445 471.2683 Glyceraldehyde-3-phosphate dehydrogenase OS=Homo sapiens OX=9606 GN=GAPDH PE=1 SV=3 8.75 3025.3 - 562741 - - - -2.5752 - 2.325 0.431 - 279.6 1 2 0 -0.0036 15 0 0 0 1.14E+07 2.18E+07 - - - 5.5458 0.9877 221125_WJC_METTL3_EV_vs_WT_F05.17755.17755.2 1.33 12-May R.MTLDDFR.L "sp|P35527|K1C9_HUMAN,tr|K7EQQ3|K7EQQ3_HUMAN" 2 896.4062 3.36 68928 17755 2 896.405826 449.2104 "Keratin, type I cytoskeletal 9 OS=Homo sapiens OX=9606 GN=KRT9 PE=1 SV=3" 4.21 3025.6 - 296447 - - - -0.4206 - 1.189 0.14 - 92.3 2 2 0 -0.0004 7 0 0 0 3.01E+06 8.94E+05 - - - 0.489 0.9999 221125_WJC_METTL3_EV_vs_WT_F05.17762.17762.3 4.97E-05 13/68 R.DEATAAVIDLNDR[166.11]PIGSR[166.11].K sp|Q9NTZ6|RBM12_HUMAN 1 1931.9816 1.09 68933 17762 3 1931.985106 645.0011 RNA-binding protein 12 OS=Homo sapiens OX=9606 GN=RBM12 PE=1 SV=1 4.23 3026.5 - 300431 - - - 1.8359 - 2.48 0.509 - 209.4 1 2 0 0.0035 18 0 0 0 6.13E+06 5.64E+06 - - - 6.4755 1 221125_WJC_METTL3_EV_vs_WT_F05.17763.17763.3 3.36E-09 20/84 R.ALSAVHSPTFC[160.03]QLAC[160.03]GQDGQLK[136.11].G "sp|Q8IY67|RAVR1_HUMAN,tr|E9PAU2|E9PAU2_HUMAN,tr|A0A087WZ13|A0A087WZ13_HUMAN" 3 2395.1504 1.39 68934 17763 3 2395.149104 799.3907 Ribonucleoprotein PTB-binding 1 OS=Homo sapiens OX=9606 GN=RAVER1 PE=1 SV=1 6.77 3026.6 - 831339 - - - -0.5411 - 3.535 0.648 - 451.9 1 2 0 -0.0013 22 0 0 0 3.01E+08 2.17E+08 - - - 8.7579 0.9961 221125_WJC_METTL3_EV_vs_WT_F05.17764.17764.3 4.14E-07 15/56 K.FQSIVIGC[160.03]ALEDQK[136.11]K[136.11].L sp|O95816|BAG2_HUMAN 1 1750.9259 1.06 68935 17764 3 1751.933635 584.6492 BAG family molecular chaperone regulator 2 OS=Homo sapiens OX=9606 GN=BAG2 PE=1 SV=1 6.06 3026.7 - 803501 - - - 575.5692 - 2.772 0.449 - 265.2 1 2 0 1.0078 15 0 0 0 1.07E+07 1.01E+07 - - - 5.9272 0.9889 221125_WJC_METTL3_EV_vs_WT_F05.17769.17769.2 0.423 16-Jul R.VLQALEGLK[136.11].M "sp|P39019|RS19_HUMAN,tr|A0A075B6E2|A0A075B6E2_HUMAN" 2 977.6001 1.36 68940 17769 2 977.598294 489.8073 40S ribosomal protein S19 OS=Homo sapiens OX=9606 GN=RPS19 PE=1 SV=2 5.97 3027.4 - 246359 - - - -1.829 - 1.184 0.198 - 90 1 2 0 -0.0018 9 0 0 0 1.84E+06 1.35E+06 - - - 0.9915 1 221125_WJC_METTL3_EV_vs_WT_F05.17773.17773.3 7.48E-12 22/72 R.EGR[166.11]PSGEAFVELESEEEVK[136.11].L sp|P55795|HNRH2_HUMAN 1 2138.0134 1.49 68942 17773 3 2138.015056 713.6784 Heterogeneous nuclear ribonucleoprotein H2 OS=Homo sapiens OX=9606 GN=HNRNPH2 PE=1 SV=1 4.12 3027.9 - 2.43E+06 - - - 0.761 - 4.55 0.655 - 695 1 2 0 0.0016 19 0 0 0 1.05E+08 7.07E+07 - - - 9.5645 1 221125_WJC_METTL3_EV_vs_WT_F05.17774.17774.3 5.78E-10 22/88 R.GPAAGTEEASELAEVPAAAGETR.G sp|Q9NP08|HMX1_HUMAN 1 2183.0342 2.83 68943 17774 3 2183.037611 728.6853 Homeobox protein HMX1 OS=Homo sapiens OX=9606 GN=HMX1 PE=2 SV=2 3.98 3028 - 696125 - - - 1.5533 - 3.254 0.515 - 313.2 1 2 0 0.0034 23 0 0 0 4.62E+06 1.63E+06 - - - 7.0487 1 221125_WJC_METTL3_EV_vs_WT_F05.17775.17775.4 7.14E-06 14/78 K.AVDIPHMDIEALK[136.11]K[136.11].L sp|P62906|RL10A_HUMAN 1 1594.8724 0.77 68944 17775 4 1594.874595 399.7254 60S ribosomal protein L10a OS=Homo sapiens OX=9606 GN=RPL10A PE=1 SV=2 5.38 3028.1 - 691438 - - - 1.3989 - 2.111 0.525 - 104.1 1 2 0 0.0022 14 0 0 0 3.91E+06 5.05E+06 - - - 4.0669 1 221125_WJC_METTL3_EV_vs_WT_F05.17776.17776.3 9.40E-06 20/76 R.ASLENVHPPIAPPPTEIPER.F "sp|Q75N03|HAKAI_HUMAN,tr|C9J2P9|C9J2P9_HUMAN" 2 2163.1324 0.72 68945 17776 3 2163.136157 722.0514 E3 ubiquitin-protein ligase Hakai OS=Homo sapiens OX=9606 GN=CBLL1 PE=1 SV=1 4.75 3028.3 - 472140 - - - 1.7285 - 3.73 0.556 - 394.1 1 2 0 0.0037 20 0 0 0 9.81E+06 1.36E+07 - - - 7.9315 1 221125_WJC_METTL3_EV_vs_WT_F05.17777.17777.3 5.05E-07 17/68 R.DEATAAVIDLNDRPIGSR.K sp|Q9NTZ6|RBM12_HUMAN 1 1911.965 1.09 68946 17777 3 1911.964882 638.3289 RNA-binding protein 12 OS=Homo sapiens OX=9606 GN=RBM12 PE=1 SV=1 4.23 3028.4 - 425112 - - - -0.0717 - 2.702 0.514 - 449.4 1 2 0 -0.0001 18 0 0 0 6.13E+06 5.64E+06 - - - 6.7457 0.9535 221125_WJC_METTL3_EV_vs_WT_F05.17781.17781.3 0.109 May-36 R.DSFPWEVPKK.L sp|P31153|METK2_HUMAN 1 1231.6237 1.05 68950 17781 3 1231.623924 411.5485 S-adenosylmethionine synthase isoform type-2 OS=Homo sapiens OX=9606 GN=MAT2A PE=1 SV=1 6.07 3028.9 - 171091 - - - 0.1624 - 1.065 0.22 - 25.3 4 2 0 0.0002 10 0 0 0 7.36E+05 7.03E+05 - - - 0.898 1 221125_WJC_METTL3_EV_vs_WT_F05.17785.17785.4 1.68E-08 14/78 K.HWPFMVVNDAGR[166.11]PK[136.11].V "sp|P11142|HSP7C_HUMAN,tr|E9PQQ4|E9PQQ4_HUMAN,tr|E9PNE6|E9PNE6_HUMAN,tr|E9PKE3|E9PKE3_HUMAN,tr|E9PN89|E9PN89_HUMAN,tr|E9PLF4|E9PLF4_HUMAN,tr|E9PK54|E9PK54_HUMAN,tr|E9PN25|E9PN25_HUMAN,tr|E9PPY6|E9PPY6_HUMAN,tr|E9PQK7|E9PQK7_HUMAN" 10 1670.847 0.13 68953 17785 4 1670.848381 418.719 Heat shock cognate 71 kDa protein OS=Homo sapiens OX=9606 GN=HSPA8 PE=1 SV=1 8.75 3029.4 - 1.63E+07 - - - 0.805 - 2.868 0.532 - 210.7 1 2 0 0.0013 14 0 0 0 3.48E+07 2.68E+08 - - - 4.2396 1 221125_WJC_METTL3_EV_vs_WT_F05.17788.17788.3 5.39E-07 15/52 R.DTGTEALTPHIWNR.L sp|P48634|PRC2A_HUMAN 1 1609.7849 0.99 68956 17788 3 1609.788197 537.6022 Protein PRRC2A OS=Homo sapiens OX=9606 GN=PRRC2A PE=1 SV=3 5.32 3029.6 - 1.61E+06 - - - 2.0674 - 2.793 0.566 - 319.7 1 2 0 0.0033 14 0 0 0 1.79E+07 1.81E+07 - - - 7.579 0.9969 221125_WJC_METTL3_EV_vs_WT_F05.17790.17790.3 9.11E-06 13/48 K.LKDLFDYSPPLHK.N "sp|Q9NYF8|BCLF1_HUMAN,tr|E9PKI6|E9PKI6_HUMAN,tr|A0A1W2PQ43|A0A1W2PQ43_HUMAN,tr|E9PK91|E9PK91_HUMAN,tr|E9PK09|E9PK09_HUMAN,tr|E9PQN2|E9PQN2_HUMAN" 6 1571.8348 0.08 68958 17790 3 1571.84309 524.9522 Bcl-2-associated transcription factor 1 OS=Homo sapiens OX=9606 GN=BCLAF1 PE=1 SV=2 6.75 3029.8 - 1.14E+06 - - - 5.2868 - 2.434 0.485 - 227.3 1 2 1 0.0083 13 0 0 0 8.67E+06 1.02E+08 - - - 6.3568 1 221125_WJC_METTL3_EV_vs_WT_F05.17791.17791.3 1.55E-12 22/84 R.LASEPQDPAAVSLPTSSVPETR.G "sp|Q6P582|MZT2A_HUMAN,sp|Q6NZ67|MZT2B_HUMAN,tr|H7C202|H7C202_HUMAN,tr|B8ZZ87|B8ZZ87_HUMAN,tr|A0A494C0V9|A0A494C0V9_HUMAN,tr|H7BZ50|H7BZ50_HUMAN,tr|H7C173|H7C173_HUMAN" 7 2251.1332 2.54 68959 17791 3 2251.135565 751.385 Mitotic-spindle organizing protein 2A OS=Homo sapiens OX=9606 GN=MZT2A PE=1 SV=2 4.14 3029.9 - 889563 - - - 1.0479 - 3.812 0.639 - 357.4 1 2 0 0.0024 22 0 0 0 4.75E+06 1.87E+06 - - - 8.8361 1 221125_WJC_METTL3_EV_vs_WT_F05.17793.17793.3 1.68E-09 22/76 R.DILELGGPEGDAASGTISKK.D "sp|Q9NPF5|DMAP1_HUMAN,tr|Q5TG39|Q5TG39_HUMAN,tr|Q5TG38|Q5TG38_HUMAN,tr|Q5TG40|Q5TG40_HUMAN,tr|Q5TG36|Q5TG36_HUMAN" 5 1957.0004 1.63 68961 17793 3 1957.002125 653.3407 DNA methyltransferase 1-associated protein 1 OS=Homo sapiens OX=9606 GN=DMAP1 PE=1 SV=1 4.32 3030.1 - 776558 - - - 0.8809 - 4.329 0.592 - 510.4 1 2 0 0.0017 20 0 0 0 5.23E+07 3.20E+07 - - - 8.6947 1 221125_WJC_METTL3_EV_vs_WT_F05.17795.17795.3 1.50E-11 20/76 R.DILELGGPEGDAASGTISK[136.11]K[136.11].D "sp|Q9NPF5|DMAP1_HUMAN,tr|Q5TG39|Q5TG39_HUMAN,tr|Q5TG38|Q5TG38_HUMAN,tr|Q5TG40|Q5TG40_HUMAN,tr|Q5TG36|Q5TG36_HUMAN" 5 1973.0288 1.67 68963 17795 3 1973.03143 658.6835 DNA methyltransferase 1-associated protein 1 OS=Homo sapiens OX=9606 GN=DMAP1 PE=1 SV=1 4.32 3030.3 - 612216 - - - 1.3325 - 4.195 0.649 - 346.9 1 2 0 0.0026 20 0 0 0 5.41E+07 3.24E+07 - - - 9.2536 0.9999 221125_WJC_METTL3_EV_vs_WT_F05.17797.17797.3 0.0049 15/52 K.AVDIPHMDIEALK[136.11]K[136.11].L sp|P62906|RL10A_HUMAN 1 1594.8724 2.03 68965 17797 3 1594.877346 532.6314 60S ribosomal protein L10a OS=Homo sapiens OX=9606 GN=RPL10A PE=1 SV=2 5.38 3030.6 - 365522 - - - 3.1238 - 2.659 0.492 - 229.2 1 2 0 0.005 14 0 0 0 3.68E+06 1.81E+06 - - - 6.6229 0.9999 221125_WJC_METTL3_EV_vs_WT_F05.17799.17799.3 0.000556 Nov-52 K.AVDIPHMDIEALKK.L sp|P62906|RL10A_HUMAN 1 1578.844 1.99 68967 17799 3 1578.844662 527.2886 60S ribosomal protein L10a OS=Homo sapiens OX=9606 GN=RPL10A PE=1 SV=2 5.38 3030.9 - 305973 - - - 0.4421 - 2.35 0.437 - 92.9 1 2 0 0.0007 14 0 0 0 3.74E+06 1.88E+06 - - - 5.6826 1 221125_WJC_METTL3_EV_vs_WT_F05.17801.17801.2 5.17E-10 13/32 A.NAGPNTNGSQFFIC[160.03]TAK.T "sp|P0DN37|PAL4G_HUMAN,sp|A0A0B4J2A2|PAL4C_HUMAN,sp|P62937|PPIA_HUMAN,tr|C9J5S7|C9J5S7_HUMAN,tr|A0A7I2V4V1|A0A7I2V4V1_HUMAN,tr|F8WE65|F8WE65_HUMAN" 6 1825.8417 1.48 68969 17801 2 1825.845657 913.9281 Peptidyl-prolyl cis-trans isomerase A-like 4G OS=Homo sapiens OX=9606 GN=PPIAL4G PE=3 SV=1 8.22 3031.1 - 267612 - - - 2.1491 - 2.997 0.709 - 569.1 1 1 0 0.0039 17 0 0 0 2.13E+06 1.44E+06 - - - 6.975 1 221125_WJC_METTL3_EV_vs_WT_F05.17804.17804.4 3.04E-09 16/78 K.HWPFMVVNDAGRPK.V "sp|P11142|HSP7C_HUMAN,tr|E9PQQ4|E9PQQ4_HUMAN,tr|E9PNE6|E9PNE6_HUMAN,tr|E9PKE3|E9PKE3_HUMAN,tr|E9PN89|E9PN89_HUMAN,tr|E9PLF4|E9PLF4_HUMAN,tr|E9PK54|E9PK54_HUMAN,tr|E9PN25|E9PN25_HUMAN,tr|E9PPY6|E9PPY6_HUMAN,tr|E9PQK7|E9PQK7_HUMAN" 10 1652.8246 0.14 68971 17804 4 1652.825264 414.2134 Heat shock cognate 71 kDa protein OS=Homo sapiens OX=9606 GN=HSPA8 PE=1 SV=1 8.75 3031.5 - 1.89E+06 - - - 0.4223 - 2.724 0.599 - 276.3 1 2 0 0.0007 14 0 0 0 3.63E+07 2.57E+08 - - - 4.8042 0.9834 221125_WJC_METTL3_EV_vs_WT_F05.17805.17805.3 0.921 Sep-60 R.SK[136.11]FDELSASNLPPNLK[136.11].L sp|Q8N5N7|RM50_HUMAN 1 1774.9436 2.86 68972 17805 3 1774.944645 592.6551 "39S ribosomal protein L50, mitochondrial OS=Homo sapiens OX=9606 GN=MRPL50 PE=1 SV=2" 5.79 3031.7 - 296543 - - - 0.5803 - 1.649 0.234 - 59.9 1 2 1 0.001 16 0 0 0 1.67E+07 5.86E+06 - - - 2.4319 1 221125_WJC_METTL3_EV_vs_WT_F05.17806.17806.3 6.62E-12 22/72 R.EGRPSGEAFVELESEEEVK.L sp|P55795|HNRH2_HUMAN 1 2119.991 1.49 68973 17806 3 2119.991224 707.6709 Heterogeneous nuclear ribonucleoprotein H2 OS=Homo sapiens OX=9606 GN=HNRNPH2 PE=1 SV=1 4.12 3031.7 - 6.10E+06 - - - 0.125 - 4.462 0.661 - 742.7 1 2 0 0.0003 19 0 0 0 1.05E+08 7.07E+07 - - - 9.5838 1 221125_WJC_METTL3_EV_vs_WT_F05.17811.17811.3 0.000104 14/56 K.RLEITPVVC[160.03]NVEQVR.L sp|Q9UI36|DACH1_HUMAN 1 1810.9724 3.59 68978 17811 3 1810.973141 604.6647 Dachshund homolog 1 OS=Homo sapiens OX=9606 GN=DACH1 PE=1 SV=4 6.14 3032.2 - 533919 - - - 0.4351 - 3.029 0.492 - 320.3 1 2 0 0.0008 15 0 0 0 4.06E+06 1.13E+06 - - - 6.9169 0.9589 221125_WJC_METTL3_EV_vs_WT_F05.17812.17812.3 1.19E-07 17/84 K.VPEIEVTVEGPNNNNPQTSAVR.T "sp|P78347|GTF2I_HUMAN,tr|A0A494C1K3|A0A494C1K3_HUMAN" 2 2363.1717 -1 68979 17812 3 2364.154407 788.7312 General transcription factor II-I OS=Homo sapiens OX=9606 GN=GTF2I PE=1 SV=2 4.25 3032.3 - 483542 - - - 415.8352 - 3.298 0.625 - 271.1 1 2 0 0.9827 22 0 0 0 0.00E+00 0.00E+00 - - - 8.0651 0.9858 221125_WJC_METTL3_EV_vs_WT_F05.17813.17813.2 5.60E-05 30-Sep S.TASAVPELATDPELEK[136.11].K "sp|Q86U44|MTA70_HUMAN,tr|B4E349|B4E349_HUMAN,tr|F5H6D8|F5H6D8_HUMAN,tr|H0YFV6|H0YFV6_HUMAN,tr|B4DTN4|B4DTN4_HUMAN" 5 1677.8552 9.81 68980 17813 2 1677.853276 839.9349 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 4 3032.4 - 337973 - - - -1.1747 - 1.942 0.477 - 186.3 1 1 0 -0.002 16 0 0 0 3.86E+07 3.93E+06 - - - 4.1953 1 221125_WJC_METTL3_EV_vs_WT_F05.17822.17822.3 2.45E-08 17/76 K.QPAIMPGQSYGLEDGSC[160.03]SYK.D "sp|P14866|HNRPL_HUMAN,tr|M0QYT0|M0QYT0_HUMAN,tr|A0A3B3ITJ4|A0A3B3ITJ4_HUMAN,tr|M0QXS5|M0QXS5_HUMAN" 4 2186.9613 1.44 68987 17822 3 2186.96156 729.9944 Heterogeneous nuclear ribonucleoprotein L OS=Homo sapiens OX=9606 GN=HNRNPL PE=1 SV=2 4.37 3033.5 - 1.36E+06 - - - 0.1395 - 2.866 0.596 - 335.6 1 2 0 0.0003 20 0 0 0 2.04E+07 1.41E+07 - - - 7.7391 1 221125_WJC_METTL3_EV_vs_WT_F05.17824.17824.2 1.30E-08 14/26 K.WNLLQQQTTTTSSK.N sp|P19013|K2C4_HUMAN 1 1634.8264 3.64 68989 17824 2 1634.823901 818.4205 "Keratin, type II cytoskeletal 4 OS=Homo sapiens OX=9606 GN=KRT4 PE=1 SV=5" 8.75 3033.8 - 571579 - - - -1.5286 - 2.452 0.629 - 533.6 1 2 0 -0.0025 14 0 0 0 6.14E+06 1.69E+06 - - - 5.9367 0.9998 221125_WJC_METTL3_EV_vs_WT_F05.17826.17826.3 5.43E-06 13/68 K.FNPDEDKQNLFVAGMSDK.K "sp|O60508|PRP17_HUMAN,tr|Q5SRN1|Q5SRN1_HUMAN" 2 2053.9415 12.15 68991 17826 3 2053.937303 685.6544 Pre-mRNA-processing factor 17 OS=Homo sapiens OX=9606 GN=CDC40 PE=1 SV=1 4.23 3034 - 487359 - - - -2.0463 - 2.676 0.53 - 230.7 1 2 1 -0.0042 18 0 0 0 6.79E+06 5.59E+05 - - - 6.8989 1 221125_WJC_METTL3_EV_vs_WT_F05.17827.17827.3 1.88E-09 Nov-40 R.THSDQFLVAFK[136.11].E sp|P36542|ATPG_HUMAN 1 1299.6703 1.7 68992 17827 3 1299.666763 434.2307 "ATP synthase subunit gamma, mitochondrial OS=Homo sapiens OX=9606 GN=ATP5F1C PE=1 SV=1" 6.41 3034.1 - 463563 - - - -2.7115 - 2.421 0.606 - 183.4 1 2 0 -0.0035 11 0 0 0 3.44E+06 2.03E+06 - - - 7.8071 0.9933 221125_WJC_METTL3_EV_vs_WT_F05.17828.17828.3 3.68E-08 16/84 K.VPEIEVTVEGPNNNNPQTSAVR[166.11].T "sp|P78347|GTF2I_HUMAN,tr|A0A494C1K3|A0A494C1K3_HUMAN" 2 2373.18 0.001 68993 17828 3 2374.171711 792.0673 General transcription factor II-I OS=Homo sapiens OX=9606 GN=GTF2I PE=1 SV=2 4.25 3034.3 - 459215 - - - 417.8882 - 3.092 0.583 - 228.9 1 2 0 0.9917 22 0 0 0 0.00E+00 2.18E+06 - - - 7.4414 1 221125_WJC_METTL3_EV_vs_WT_F05.17829.17829.3 8.76E-08 13/52 K.K[136.11]VIQYLAYVASSHK[136.11].S "sp|P35579|MYH9_HUMAN,tr|Q5BKV1|Q5BKV1_HUMAN" 2 1621.9163 0.83 68994 17829 3 1621.916152 541.646 Myosin-9 OS=Homo sapiens OX=9606 GN=MYH9 PE=1 SV=4 9.53 3034.4 - 452181 - - - -0.0777 - 2.771 0.572 - 165.2 1 2 0 -0.0001 14 0 0 0 5.93E+06 7.12E+06 - - - 7.6258 1 221125_WJC_METTL3_EV_vs_WT_F05.17833.17833.3 4.30E-06 20/84 R.ALSAVHSPTFC[160.03]QLAC[160.03]GQDGQLK.G "sp|Q8IY67|RAVR1_HUMAN,tr|E9PAU2|E9PAU2_HUMAN,tr|A0A087WZ13|A0A087WZ13_HUMAN" 3 2387.1362 1.4 68996 17833 3 2387.128386 796.7193 Ribonucleoprotein PTB-binding 1 OS=Homo sapiens OX=9606 GN=RAVER1 PE=1 SV=1 6.77 3034.9 - 7.37E+06 - - - -3.2734 - 3.551 0.589 - 417.5 1 2 0 -0.0078 22 0 0 0 3.03E+08 2.17E+08 - - - 8.109 0.9478 221125_WJC_METTL3_EV_vs_WT_F05.17834.17834.2 0.268 Jul-34 S.GVSPTC[160.03]SDHC[160.03]PYQSPPSK.A "sp|Q86YN6|PRGC2_HUMAN,tr|H0Y713|H0Y713_HUMAN" 2 2002.8513 999 68997 17834 2 2002.849639 1002.4329 Peroxisome proliferator-activated receptor gamma coactivator 1-beta OS=Homo sapiens OX=9606 GN=PPARGC1B PE=1 SV=2 6.72 3035 - 6.76E+06 - - - -0.8348 - 1.554 0.329 - 81.9 1 1 0 -0.0017 18 0 0 0 7.62E+08 0.00E+00 - - - 2.5543 0.9998 221125_WJC_METTL3_EV_vs_WT_F05.17839.17839.3 8.06E-05 Nov-64 K.FSSSGDFLVAGVGQEHR[166.11].L sp|O43818|U3IP2_HUMAN 1 1801.8623 0.99 69002 17839 3 1801.857601 601.628 U3 small nucleolar RNA-interacting protein 2 OS=Homo sapiens OX=9606 GN=RRP9 PE=1 SV=1 5.32 3035.5 - 821789 - - - -2.5973 - 2.33 0.461 - 129.2 1 2 0 -0.0047 17 0 0 0 1.07E+07 1.08E+07 - - - 5.8153 0.9999 221125_WJC_METTL3_EV_vs_WT_F05.17842.17842.4 4.40E-06 13/78 K.AVDIPHMDIEALKK.L sp|P62906|RL10A_HUMAN 1 1578.844 0.98 69003 17842 4 1578.839344 395.7183 60S ribosomal protein L10a OS=Homo sapiens OX=9606 GN=RPL10A PE=1 SV=2 5.38 3035.9 - 6.39E+06 - - - -2.9262 - 2.386 0.548 - 96.2 1 2 0 -0.0046 14 0 0 0 3.84E+08 3.91E+08 - - - 4.311 1 221125_WJC_METTL3_EV_vs_WT_F05.17848.17848.3 9.90E-10 15/52 K.HWPFMVVNDAGR[166.11]PK[136.11].V "sp|P11142|HSP7C_HUMAN,tr|E9PQQ4|E9PQQ4_HUMAN,tr|E9PNE6|E9PNE6_HUMAN,tr|E9PKE3|E9PKE3_HUMAN,tr|E9PN89|E9PN89_HUMAN,tr|E9PLF4|E9PLF4_HUMAN,tr|E9PK54|E9PK54_HUMAN,tr|E9PN25|E9PN25_HUMAN,tr|E9PPY6|E9PPY6_HUMAN,tr|E9PQK7|E9PQK7_HUMAN" 10 1670.847 0.14 69006 17848 3 1670.842104 557.9563 Heat shock cognate 71 kDa protein OS=Homo sapiens OX=9606 GN=HSPA8 PE=1 SV=1 8.75 3036.7 - 2.81E+07 - - - -2.9518 - 2.935 0.6 - 383 1 2 0 -0.0049 14 0 0 0 1.38E+08 9.71E+08 - - - 8.0894 1 221125_WJC_METTL3_EV_vs_WT_F05.17871.17871.3 7.71E-09 26/64 L.LNGEQAEAAINAFHQSR[166.11].L "sp|Q8IY67|RAVR1_HUMAN,tr|E9PAU2|E9PAU2_HUMAN,tr|A0A087WZ13|A0A087WZ13_HUMAN" 3 1864.9055 1.02 69011 17871 3 1864.899091 622.6425 Ribonucleoprotein PTB-binding 1 OS=Homo sapiens OX=9606 GN=RAVER1 PE=1 SV=1 5.4 3040 - 2.03E+06 - - - -3.4597 - 4.069 0.589 - 1108.8 1 1 0 -0.0065 17 0 0 0 4.31E+07 4.22E+07 - - - 8.6504 1 221125_WJC_METTL3_EV_vs_WT_F05.17880.17880.3 5.59E-07 25/64 L.LNGEQAEAAINAFHQSR.L "sp|Q8IY67|RAVR1_HUMAN,tr|E9PAU2|E9PAU2_HUMAN,tr|A0A087WZ13|A0A087WZ13_HUMAN" 3 1854.8973 1.01 69014 17880 3 1854.895302 619.3064 Ribonucleoprotein PTB-binding 1 OS=Homo sapiens OX=9606 GN=RAVER1 PE=1 SV=1 5.4 3041.2 - 1.46E+06 - - - -1.0626 - 4.83 0.545 - 1122.3 1 1 0 -0.002 17 0 0 0 4.22E+07 4.19E+07 - - - 8.5942 0.9948 221125_WJC_METTL3_EV_vs_WT_F05.17884.17884.3 6.42E-07 13/44 V.DIPHMDIEALK[136.11]K[136.11].L sp|P62906|RL10A_HUMAN 1 1424.7668 1.06 69016 17884 3 1424.763889 475.9296 60S ribosomal protein L10a OS=Homo sapiens OX=9606 GN=RPL10A PE=1 SV=2 5.38 3041.7 - 612416 - - - -2.0684 - 2.366 0.516 - 138.1 1 1 0 -0.0029 12 0 0 0 2.10E+07 1.98E+07 - - - 6.6792 0.9997 221125_WJC_METTL3_EV_vs_WT_F05.17888.17888.3 6.31E-06 17/52 K.DFKDGTFDPDNLEK.Y sp|Q8IXM3|RM41_HUMAN 1 1639.7366 1.97 69018 17888 3 1639.730939 547.5861 "39S ribosomal protein L41, mitochondrial OS=Homo sapiens OX=9606 GN=MRPL41 PE=1 SV=1" 4.04 3042.2 - 2.21E+06 - - - -3.4414 - 2.725 0.594 - 302.6 1 2 1 -0.0056 14 0 0 0 4.98E+07 2.53E+07 - - - 7.825 1 221125_WJC_METTL3_EV_vs_WT_F05.17889.17889.3 2.35E-11 21/68 K.MVMIQDGPLPTGADKPLR.L sp|Q96I24|FUBP3_HUMAN 1 1938.0067 1.64 69019 17889 3 1937.998048 647.0095 Far upstream element-binding protein 3 OS=Homo sapiens OX=9606 GN=FUBP3 PE=1 SV=2 5.71 3042.3 - 1.60E+06 - - - -4.4587 - 3.789 0.637 - 521.1 1 2 0 -0.0086 18 0 0 0 2.93E+07 1.79E+07 - - - 8.9566 0.9979 221125_WJC_METTL3_EV_vs_WT_F05.17893.17893.3 2.08E-05 Dec-52 K.DFK[136.11]DGTFDPDNLEK[136.11].Y sp|Q8IXM3|RM41_HUMAN 1 1655.765 1.97 69020 17893 3 1655.758942 552.9289 "39S ribosomal protein L41, mitochondrial OS=Homo sapiens OX=9606 GN=MRPL41 PE=1 SV=1" 4.04 3042.9 - 1.51E+06 - - - -3.6479 - 2.21 0.433 - 138.8 1 2 1 -0.006 14 0 0 0 5.00E+07 2.53E+07 - - - 5.4733 0.9996 221125_WJC_METTL3_EV_vs_WT_F05.17894.17894.3 5.13E-05 Dec-76 K.AGVPLPPNLKPAPPPTIEEK.V "sp|P18583|SON_HUMAN,tr|H7C1M2|H7C1M2_HUMAN,tr|H7C2G8|H7C2G8_HUMAN,tr|J3QSZ5|J3QSZ5_HUMAN" 4 2064.1619 4.89 69021 17894 3 2064.155631 689.0613 Protein SON OS=Homo sapiens OX=9606 GN=SON PE=1 SV=4 6.19 3043 - 627535 - - - -3.0506 - 1.952 0.439 - 118.8 1 2 0 -0.0063 20 0 0 0 2.48E+07 5.07E+06 - - - 5.0553 0.9998 221125_WJC_METTL3_EV_vs_WT_F05.17897.17897.4 0.721 15/90 K.YFLHDDRDDGVDYWAK.R "sp|Q9NYF8|BCLF1_HUMAN,tr|H0YF14|H0YF14_HUMAN" 2 2013.8857 2.36 69022 17897 4 2013.881764 504.4787 Bcl-2-associated transcription factor 1 OS=Homo sapiens OX=9606 GN=BCLAF1 PE=1 SV=2 4.28 3043.4 - 3.00E+06 - - - -1.9574 - 2.957 0.479 - 172.3 1 2 1 -0.0039 16 0 0 0 5.10E+07 2.16E+07 - - - 3.776 0.9931 221125_WJC_METTL3_EV_vs_WT_F05.17901.17901.3 0.000876 Dec-44 V.DIPHMDIEALKK.L sp|P62906|RL10A_HUMAN 1 1408.7384 1.06 69026 17901 3 1408.736256 470.5868 60S ribosomal protein L10a OS=Homo sapiens OX=9606 GN=RPL10A PE=1 SV=2 5.38 3043.9 - 658540 - - - -1.5475 - 2.272 0.458 - 111.8 1 1 0 -0.0022 12 0 0 0 2.10E+07 1.97E+07 - - - 5.9204 1 221125_WJC_METTL3_EV_vs_WT_F05.17907.17907.3 4.59E-11 25/68 K.RPDFAQQQAMQQLTFDGK.R "sp|Q9C0J8|WDR33_HUMAN,tr|B9A053|B9A053_HUMAN" 2 2108.0109 2.26 69029 17907 3 2108.010567 703.6776 pre-mRNA 3' end processing protein WDR33 OS=Homo sapiens OX=9606 GN=WDR33 PE=1 SV=2 5.96 3044.7 - 526819 - - - -0.1689 - 4.866 0.575 - 718.3 1 2 0 -0.0004 18 0 0 0 1.15E+07 5.07E+06 - - - 8.8906 0.9956 221125_WJC_METTL3_EV_vs_WT_F05.17910.17910.3 0.176 Sep-60 R.NELMQSLNQDSNSNFK[136.11].D "sp|Q15643|TRIPB_HUMAN,tr|H0YJ97|H0YJ97_HUMAN" 2 1875.8512 0.08 69032 17910 3 1875.850047 626.291 Thyroid receptor-interacting protein 11 OS=Homo sapiens OX=9606 GN=TRIP11 PE=1 SV=3 4.37 3045.1 - 649359 - - - -0.6365 - 1.697 0.217 - 84.1 1 2 0 -0.0012 16 0 0 0 2.35E+05 3.09E+06 - - - 2.316 1 221125_WJC_METTL3_EV_vs_WT_F05.17913.17913.4 1.63E-07 16/96 K.LLHSFHSELPVLSDSER.D "sp|Q99567|NUP88_HUMAN,tr|J3KMX1|J3KMX1_HUMAN" 2 1964.9956 2.95 69033 17913 4 1964.99684 492.2562 Nuclear pore complex protein Nup88 OS=Homo sapiens OX=9606 GN=NUP88 PE=1 SV=2 5.27 3045.5 - 730578 - - - 0.6361 - 3.04 0.495 - 199.3 1 2 0 0.0012 17 0 0 0 2.03E+07 6.89E+06 - - - 3.9202 1 221125_WJC_METTL3_EV_vs_WT_F05.17917.17917.3 1.21E-07 19/64 K.LLHSFHSELPVLSDSER.D "sp|Q99567|NUP88_HUMAN,tr|J3KMX1|J3KMX1_HUMAN" 2 1964.9956 5.63 69037 17917 3 1964.998431 656.0058 Nuclear pore complex protein Nup88 OS=Homo sapiens OX=9606 GN=NUP88 PE=1 SV=2 5.27 3046 - 673630 - - - 1.4458 - 3.366 0.563 - 492.6 1 2 0 0.0028 17 0 0 0 1.25E+07 2.23E+06 - - - 7.8823 1 221125_WJC_METTL3_EV_vs_WT_F05.17919.17919.3 9.42E-07 17/76 R.LPLQLDDAVRPEAEGEEEGR.A "sp|P14868|SYDC_HUMAN,tr|C9J7S3|C9J7S3_HUMAN,tr|C9JLC1|C9JLC1_HUMAN" 3 2222.0815 1.43 69039 17919 3 2222.079357 741.7011 "Aspartate--tRNA ligase, cytoplasmic OS=Homo sapiens OX=9606 GN=DARS1 PE=1 SV=2" 4 3046.3 - 545044 - - - -0.9667 - 2.924 0.575 - 387.7 1 2 0 -0.0021 20 0 0 0 2.51E+07 1.75E+07 - - - 7.5531 0.9972 221125_WJC_METTL3_EV_vs_WT_F05.17920.17920.3 0.0524 Sep-44 K.EKPVDLQNFGLR.T sp|Q92922|SMRC1_HUMAN 1 1414.7569 1.83 69040 17920 3 1414.7571 472.5929 SWI\SNF complex subunit SMARCC1 OS=Homo sapiens OX=9606 GN=SMARCC1 PE=1 SV=3 6.17 3046.4 - 414806 - - - 0.1668 - 1.634 0.242 - 129.8 1 2 0 0.0002 12 0 0 0 8.56E+06 4.68E+06 - - - 2.5991 1 221125_WJC_METTL3_EV_vs_WT_F05.17921.17921.3 2.50E-06 21/68 K.R[166.11]PDFAQQQAMQQLTFDGK[136.11].R "sp|Q9C0J8|WDR33_HUMAN,tr|B9A053|B9A053_HUMAN" 2 2126.0334 2.68 69041 17921 3 2126.028855 709.6851 pre-mRNA 3' end processing protein WDR33 OS=Homo sapiens OX=9606 GN=WDR33 PE=1 SV=2 5.96 3046.5 - 359766 - - - -2.1345 - 4.498 0.604 - 911.5 1 2 0 -0.0045 18 0 0 0 1.09E+07 4.05E+06 - - - 9.0169 1 221125_WJC_METTL3_EV_vs_WT_F05.17924.17924.3 0.00129 18/52 K.KGGSFQLNELQGLK.S "sp|P02788|TRFL_HUMAN,tr|C9JCF5|C9JCF5_HUMAN,tr|E7EQB2|E7EQB2_HUMAN,tr|E7ER44|E7ER44_HUMAN" 4 1517.8202 999 69042 17924 3 1517.822157 506.9473 Lactotransferrin OS=Homo sapiens OX=9606 GN=LTF PE=1 SV=6 8.59 3046.9 - 1.05E+06 - - - 1.2946 - 3.174 0.529 - 384.6 1 2 0 0.002 14 0 0 0 3.03E+07 0.00E+00 - - - 7.5067 1 221125_WJC_METTL3_EV_vs_WT_F05.17925.17925.3 2.57E-08 19/64 R.DVQGTDASLDEELDR[166.11]VK[136.11].M "sp|Q9UJZ1|STML2_HUMAN,tr|A0A087WYB4|A0A087WYB4_HUMAN" 2 1906.9239 2.32 69043 17925 3 1906.923457 636.6486 "Stomatin-like protein 2, mitochondrial OS=Homo sapiens OX=9606 GN=STOML2 PE=1 SV=1" 3.96 3047 - 963855 - - - -0.2244 - 3.511 0.576 - 260.6 1 2 1 -0.0004 17 0 0 0 7.66E+07 3.30E+07 - - - 8.1345 1 221125_WJC_METTL3_EV_vs_WT_F05.17926.17926.2 2.23E-07 26-Nov K.HTDESLGDC[160.03]SFLNT.C "sp|Q86U44|MTA70_HUMAN,tr|H0YFV6|H0YFV6_HUMAN" 2 1594.657 - 69044 17926 2 1594.669889 798.3358 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 4.02 3047.1 - 874703 - - - 8.1133 - 2.413 0.675 - 260.7 1 1 0 0.0129 14 0 0 0 - - - - - 6.233 0.8931 221125_WJC_METTL3_EV_vs_WT_F05.17927.17927.3 0.0315 Dec-76 R.APGVYVGTAPSGC[160.03]IGGLGAR.V sp|Q13515|BFSP2_HUMAN 1 1858.936 6.51 69045 17927 3 1858.922233 620.6526 Phakinin OS=Homo sapiens OX=9606 GN=BFSP2 PE=1 SV=1 8.27 3047.3 - 607040 - - - -7.3881 - 2.249 0.227 - 90.8 1 2 0 -0.0137 20 0 0 0 1.09E+07 1.68E+06 - - - 3.0333 1 221125_WJC_METTL3_EV_vs_WT_F05.17929.17929.2 3.01E-10 13/32 K.NETLGGTC[160.03]LNVGC[160.03]IPSK.A "sp|P09622|DLDH_HUMAN,tr|F8WDM5|F8WDM5_HUMAN,tr|F2Z2E3|F2Z2E3_HUMAN,tr|A0A1W2PR83|A0A1W2PR83_HUMAN" 4 1818.8604 1.59 69047 17929 2 1818.862111 910.4375 "Dihydrolipoyl dehydrogenase, mitochondrial OS=Homo sapiens OX=9606 GN=DLD PE=1 SV=2" 5.99 3047.5 - 465574 - - - 0.9303 - 2.928 0.697 - 417.1 1 2 0 0.0017 17 0 0 0 1.02E+07 6.38E+06 - - - 6.8298 0.9998 221125_WJC_METTL3_EV_vs_WT_F05.17931.17931.4 0.000156 13/96 K.LLHSFHSELPVLSDSER[166.11].D "sp|Q99567|NUP88_HUMAN,tr|J3KMX1|J3KMX1_HUMAN" 2 1975.0039 2.95 69049 17931 4 1975.003956 494.7582 Nuclear pore complex protein Nup88 OS=Homo sapiens OX=9606 GN=NUP88 PE=1 SV=2 5.27 3047.8 - 403078 - - - 0.0486 - 2.194 0.379 - 78.2 1 2 0 0.0001 17 0 0 0 2.03E+07 6.89E+06 - - - 2.7976 1 221125_WJC_METTL3_EV_vs_WT_F05.17932.17932.3 1.93E-08 17/56 K.QC[160.03]ANLQNAIADAEQR.G "sp|P13647|K2C5_HUMAN,tr|H0YI76|H0YI76_HUMAN" 2 1700.79 1.13 69050 17932 3 1700.791325 567.9373 "Keratin, type II cytoskeletal 5 OS=Homo sapiens OX=9606 GN=KRT5 PE=1 SV=3" 4.37 3047.9 - 364186 - - - 0.7608 - 2.967 0.556 - 360.8 1 2 0 0.0013 15 0 0 0 1.09E+08 9.70E+07 - - - 7.5763 0.9993 221125_WJC_METTL3_EV_vs_WT_F05.17933.17933.3 0.00211 Oct-76 K.AGVPLPPNLK[136.11]PAPPPTIEEK[136.11].V "sp|P18583|SON_HUMAN,tr|H7C1M2|H7C1M2_HUMAN,tr|H7C2G8|H7C2G8_HUMAN,tr|J3QSZ5|J3QSZ5_HUMAN" 4 2080.1903 5.05 69051 17933 3 2080.189737 694.4041 Protein SON OS=Homo sapiens OX=9606 GN=SON PE=1 SV=4 6.19 3048.1 - 263670 - - - -0.2841 - 1.776 0.328 - 86.2 1 2 0 -0.0006 20 0 0 0 1.08E+07 2.15E+06 - - - 3.5901 0.962 221125_WJC_METTL3_EV_vs_WT_F05.17934.17934.3 8.12E-05 Dec-44 L.KDLFDYSPPLHK.N "sp|Q9NYF8|BCLF1_HUMAN,tr|E9PKI6|E9PKI6_HUMAN,tr|A0A1W2PQ43|A0A1W2PQ43_HUMAN,tr|E9PK91|E9PK91_HUMAN,tr|E9PK09|E9PK09_HUMAN,tr|E9PQN2|E9PQN2_HUMAN" 6 1458.7507 8.02 69052 17934 3 1458.748651 487.2575 Bcl-2-associated transcription factor 1 OS=Homo sapiens OX=9606 GN=BCLAF1 PE=1 SV=2 6.75 3048.2 - 207762 - - - -1.4156 - 2.31 0.301 - 195.9 1 1 0 -0.0021 12 0 0 0 3.35E+06 4.17E+05 - - - 4.216 0.9958 221125_WJC_METTL3_EV_vs_WT_F05.17935.17935.3 0.000167 Oct-48 Q.SIVPALEIANAHR[166.11].K "sp|P10809|CH60_HUMAN,tr|A0A7I2V2X6|A0A7I2V2X6_HUMAN,tr|A0A7I2YQK6|A0A7I2YQK6_HUMAN,tr|A0A7I2V599|A0A7I2V599_HUMAN,tr|A0A7I2YQ71|A0A7I2YQ71_HUMAN,tr|A0A7I2V5M1|A0A7I2V5M1_HUMAN,tr|A0A7I2V5K3|A0A7I2V5K3_HUMAN,tr|A0A7I2V369|A0A7I2V369_HUMAN" 8 1399.7811 1.72 69053 17935 3 1399.780709 467.601 "60 kDa heat shock protein, mitochondrial OS=Homo sapiens OX=9606 GN=HSPD1 PE=1 SV=2" 6.47 3048.3 - 145776 - - - -0.2922 - 2.333 0.476 - 128.7 1 1 0 -0.0004 13 0 0 0 2.33E+06 1.35E+06 - - - 6.1437 0.9877 221125_WJC_METTL3_EV_vs_WT_F05.17939.17939.4 0.0161 Oct-72 K.LKDLFDYSPPLHK.N "sp|Q9NYF8|BCLF1_HUMAN,tr|E9PKI6|E9PKI6_HUMAN,tr|A0A1W2PQ43|A0A1W2PQ43_HUMAN,tr|E9PK91|E9PK91_HUMAN,tr|E9PK09|E9PK09_HUMAN,tr|E9PQN2|E9PQN2_HUMAN" 6 1571.8348 2.6 69056 17939 4 1571.83445 393.966 Bcl-2-associated transcription factor 1 OS=Homo sapiens OX=9606 GN=BCLAF1 PE=1 SV=2 6.75 3048.7 - 2.64E+07 - - - -0.2099 - 1.679 0.25 - 71.3 1 2 1 -0.0003 13 0 0 0 9.83E+08 3.79E+08 - - - 1.594 0.9999 221125_WJC_METTL3_EV_vs_WT_F05.17940.17940.3 0.00202 15/48 K.LK[136.11]DLFDYSPPLHK[136.11].N "sp|Q9NYF8|BCLF1_HUMAN,tr|E9PKI6|E9PKI6_HUMAN,tr|A0A1W2PQ43|A0A1W2PQ43_HUMAN,tr|E9PK91|E9PK91_HUMAN,tr|E9PK09|E9PK09_HUMAN,tr|E9PQN2|E9PQN2_HUMAN" 6 1587.8632 3.06 69057 17940 3 1587.863701 530.295 Bcl-2-associated transcription factor 1 OS=Homo sapiens OX=9606 GN=BCLAF1 PE=1 SV=2 6.75 3048.8 - 5.27E+06 - - - 0.3281 - 2.824 0.525 - 295.8 1 2 1 0.0005 13 0 0 0 5.52E+08 1.81E+08 - - - 7.2078 0.9987 221125_WJC_METTL3_EV_vs_WT_F05.17941.17941.3 7.00E-10 19/64 R.DVQGTDASLDEELDRVK.M "sp|Q9UJZ1|STML2_HUMAN,tr|A0A087WYB4|A0A087WYB4_HUMAN" 2 1888.9014 2.33 69058 17941 3 1888.908758 630.6411 "Stomatin-like protein 2, mitochondrial OS=Homo sapiens OX=9606 GN=STOML2 PE=1 SV=1" 3.96 3048.8 - 4.57E+06 - - - 3.8874 - 2.92 0.447 - 336.2 1 2 1 0.0073 17 0 0 0 7.68E+07 3.30E+07 - - - 6.2287 0.9999 221125_WJC_METTL3_EV_vs_WT_F05.17942.17942.3 0.000132 17/64 K.SDK[136.11]TEEIAEEEETVFPK[136.11].A sp|Q9NR30|DDX21_HUMAN 1 1995.9495 1.33 69059 17942 3 1995.949851 666.3238 Nucleolar RNA helicase 2 OS=Homo sapiens OX=9606 GN=DDX21 PE=1 SV=5 4.06 3048.9 - 1.41E+06 - - - 0.1518 - 3.463 0.574 - 402.7 1 2 1 0.0003 17 0 0 0 4.38E+07 3.30E+07 - - - 8.0775 0.983 221125_WJC_METTL3_EV_vs_WT_F05.17944.17944.2 0.000429 14-Aug F.DYSPPLHK.N "sp|Q9NYF8|BCLF1_HUMAN,tr|E9PKI6|E9PKI6_HUMAN,tr|A0A1W2PQ43|A0A1W2PQ43_HUMAN,tr|E9PK91|E9PK91_HUMAN,tr|E9PK09|E9PK09_HUMAN,tr|E9PQN2|E9PQN2_HUMAN" 6 955.4763 2.93 69061 17944 2 955.476096 478.7454 Bcl-2-associated transcription factor 1 OS=Homo sapiens OX=9606 GN=BCLAF1 PE=1 SV=2 6.74 3049.1 - 789098 - - - -0.246 - 1.508 0.452 - 209.4 1 1 0 -0.0002 8 0 0 0 3.03E+07 1.04E+07 - - - 3.6183 1 221125_WJC_METTL3_EV_vs_WT_F05.17945.17945.2 9.15E-10 16/28 K.QC[160.03]ANLQNAIADAEQR.G "sp|P13647|K2C5_HUMAN,tr|H0YI76|H0YI76_HUMAN" 2 1700.79 23.02 69062 17945 2 1700.789362 851.4023 "Keratin, type II cytoskeletal 5 OS=Homo sapiens OX=9606 GN=KRT5 PE=1 SV=3" 4.37 3049.3 - 642630 - - - -0.3933 - 3.38 0.691 - 1175.8 1 2 0 -0.0007 15 0 0 0 2.45E+07 1.06E+06 - - - 7.1387 0.9999 221125_WJC_METTL3_EV_vs_WT_F05.17949.17949.4 0.000304 Dec-72 R.GLDFLHANC[160.03]IVHR[166.11].D "sp|P11802|CDK4_HUMAN,tr|F8VWX7|F8VWX7_HUMAN,tr|F8VXD2|F8VXD2_HUMAN,tr|F8VZZ0|F8VZZ0_HUMAN,tr|F8VTV8|F8VTV8_HUMAN,tr|F8VYH9|F8VYH9_HUMAN,tr|F8VZ51|F8VZ51_HUMAN" 7 1560.7859 0.49 69066 17949 4 1560.786669 391.2037 Cyclin-dependent kinase 4 OS=Homo sapiens OX=9606 GN=CDK4 PE=1 SV=2 6.91 3049.8 - 299206 - - - 0.5017 - 2.231 0.45 - 97.1 1 2 0 0.0008 13 0 0 0 1.58E+06 3.22E+06 - - - 3.4401 0.9678 221125_WJC_METTL3_EV_vs_WT_F05.17950.17950.2 0.000461 14-Jul F.DYSPPLHK[136.11].N "sp|Q9NYF8|BCLF1_HUMAN,tr|E9PKI6|E9PKI6_HUMAN,tr|A0A1W2PQ43|A0A1W2PQ43_HUMAN,tr|E9PK91|E9PK91_HUMAN,tr|E9PK09|E9PK09_HUMAN,tr|E9PQN2|E9PQN2_HUMAN" 6 963.4905 3.44 69067 17950 2 963.490753 482.7525 Bcl-2-associated transcription factor 1 OS=Homo sapiens OX=9606 GN=BCLAF1 PE=1 SV=2 6.74 3049.9 - 283418 - - - 0.2304 - 1.493 0.365 - 156.7 1 1 0 0.0002 8 0 0 0 3.01E+07 8.73E+06 - - - 2.9456 1 221125_WJC_METTL3_EV_vs_WT_F05.17951.17951.2 4.43E-09 13/30 R.QSGEAFVELGSEDDVK.M "sp|P52597|HNRPF_HUMAN,tr|A0A1B0GW42|A0A1B0GW42_HUMAN" 2 1708.7792 0.57 69068 17951 2 1708.778913 855.3969 Heterogeneous nuclear ribonucleoprotein F OS=Homo sapiens OX=9606 GN=HNRNPF PE=1 SV=3 3.83 3050 - 251974 - - - -0.1533 - 2.824 0.642 - 642.3 1 2 0 -0.0003 16 0 0 0 4.42E+06 7.82E+06 - - - 6.3351 0.9263 221125_WJC_METTL3_EV_vs_WT_F05.17952.17952.3 0.125 13/52 K.LHEWEDALVAYDKK.M sp|P42345|MTOR_HUMAN 1 1715.8519 -1 69069 17952 3 1715.838017 572.9579 Serine\threonine-protein kinase mTOR OS=Homo sapiens OX=9606 GN=MTOR PE=1 SV=1 4.75 3050.2 - 240126 - - - -8.0829 - 1.774 0.314 - 120.1 1 2 0 -0.0139 14 0 0 0 0.00E+00 0.00E+00 - - - 3.5603 0.9999 221125_WJC_METTL3_EV_vs_WT_F05.17958.17958.3 8.90E-08 15/60 K.FEKDFDFESANAQFNK.E "sp|Q8ND56|LS14A_HUMAN,tr|A0A140TA76|A0A140TA76_HUMAN,tr|K7EMZ9|K7EMZ9_HUMAN" 3 1935.8639 0.99 69073 17958 3 1935.863355 646.2952 Protein LSM14 homolog A OS=Homo sapiens OX=9606 GN=LSM14A PE=1 SV=3 4.32 3051 - 1.01E+06 - - - -0.2857 - 3.102 0.583 - 440.1 1 2 1 -0.0006 16 0 0 0 1.60E+07 1.62E+07 - - - 7.9444 1 221125_WJC_METTL3_EV_vs_WT_F05.17960.17960.3 3.12E-08 17/60 K.FEK[136.11]DFDFESANAQFNK[136.11].E "sp|Q8ND56|LS14A_HUMAN,tr|A0A140TA76|A0A140TA76_HUMAN,tr|K7EMZ9|K7EMZ9_HUMAN" 3 1951.8923 2.28 69075 17960 3 1951.893422 651.638 Protein LSM14 homolog A OS=Homo sapiens OX=9606 GN=LSM14A PE=1 SV=3 4.32 3051.2 - 1.21E+06 - - - 0.5707 - 3.246 0.6 - 459.9 1 2 1 0.0011 16 0 0 0 3.79E+07 1.66E+07 - - - 8.2502 0.9998 221125_WJC_METTL3_EV_vs_WT_F05.17962.17962.4 7.17E-06 15/90 K.YFLHDDR[166.11]DDGVDYWAK[136.11].R "sp|Q9NYF8|BCLF1_HUMAN,tr|H0YF14|H0YF14_HUMAN" 2 2031.9082 2.17 69077 17962 4 2031.909402 508.9843 Bcl-2-associated transcription factor 1 OS=Homo sapiens OX=9606 GN=BCLAF1 PE=1 SV=2 4.28 3051.4 - 669338 - - - 0.6034 - 2.447 0.495 - 159.5 1 2 1 0.0012 16 0 0 0 1.15E+09 5.27E+08 - - - 3.8494 0.9999 221125_WJC_METTL3_EV_vs_WT_F05.17964.17964.3 0.000105 17/60 K.LTEDK[136.11]ADVQSIIGLQR[166.11].F "sp|Q13263|TIF1B_HUMAN,tr|M0R0K9|M0R0K9_HUMAN" 2 1802.9857 0.79 69079 17964 3 1802.984091 602.0025 Transcription intermediary factor 1-beta OS=Homo sapiens OX=9606 GN=TRIM28 PE=1 SV=5 4.56 3051.6 - 514693 - - - -0.8913 - 2.719 0.495 - 346.3 1 2 1 -0.0016 16 0 0 0 7.12E+07 9.00E+07 - - - 6.6249 1 221125_WJC_METTL3_EV_vs_WT_F05.17965.17965.2 4.58E-11 17/30 R.QSGEAFVELGSEDDVK[136.11].M "sp|P52597|HNRPF_HUMAN,tr|A0A1B0GW42|A0A1B0GW42_HUMAN" 2 1716.7934 0.55 69080 17965 2 1716.787781 859.404 Heterogeneous nuclear ribonucleoprotein F OS=Homo sapiens OX=9606 GN=HNRNPF PE=1 SV=3 3.83 3051.8 - 414093 - - - -3.2584 - 3.254 0.648 - 1076.6 1 2 0 -0.0056 16 0 0 0 4.68E+06 8.54E+06 - - - 6.7262 0.9999 221125_WJC_METTL3_EV_vs_WT_F05.17966.17966.3 3.77E-07 14/60 K.LTEDKADVQSIIGLQR.F "sp|Q13263|TIF1B_HUMAN,tr|M0R0K9|M0R0K9_HUMAN" 2 1784.9632 0.79 69081 17966 3 1784.961849 595.995 Transcription intermediary factor 1-beta OS=Homo sapiens OX=9606 GN=TRIM28 PE=1 SV=5 4.56 3051.9 - 376521 - - - -0.7726 - 3.03 0.508 - 261.3 1 2 1 -0.0014 16 0 0 0 7.12E+07 9.00E+07 - - - 7.0477 0.9652 221125_WJC_METTL3_EV_vs_WT_F05.17968.17968.3 0.00463 Nov-48 Q.SIVPALEIANAHR.K "sp|P10809|CH60_HUMAN,tr|A0A7I2V2X6|A0A7I2V2X6_HUMAN,tr|A0A7I2YQK6|A0A7I2YQK6_HUMAN,tr|A0A7I2V599|A0A7I2V599_HUMAN,tr|A0A7I2YQ71|A0A7I2YQ71_HUMAN,tr|A0A7I2V5M1|A0A7I2V5M1_HUMAN,tr|A0A7I2V5K3|A0A7I2V5K3_HUMAN,tr|A0A7I2V369|A0A7I2V369_HUMAN" 8 1389.7728 2.37 69083 17968 3 1389.770104 464.2649 "60 kDa heat shock protein, mitochondrial OS=Homo sapiens OX=9606 GN=HSPD1 PE=1 SV=2" 6.47 3052.2 - 244079 - - - -1.9744 - 2.004 0.374 - 136.4 1 1 0 -0.0027 13 0 0 0 2.81E+06 1.18E+06 - - - 4.5937 0.9998 221125_WJC_METTL3_EV_vs_WT_F05.17969.17969.2 0.000147 22-Jul K.SSQQEFQEVFNR[166.11].S "sp|Q9BVQ7|SPA5L_HUMAN,tr|H0YCA5|H0YCA5_HUMAN" 2 1507.6931 0.66 69084 17969 2 1507.692966 754.8538 Spermatogenesis-associated protein 5-like protein 1 OS=Homo sapiens OX=9606 GN=SPATA5L1 PE=1 SV=2 4.53 3052.3 - 154525 - - - -0.0829 - 1.959 0.487 - 247.6 1 2 0 -0.0001 12 0 0 0 1.70E+06 2.57E+06 - - - 4.4072 1 221125_WJC_METTL3_EV_vs_WT_F05.17973.17973.3 4.26E-10 18/52 K.HGYIGEFEIIDDHR[166.11].A "sp|P62244|RS15A_HUMAN,tr|I3L246|I3L246_HUMAN,tr|I3L3P7|I3L3P7_HUMAN,tr|H3BN98|H3BN98_HUMAN" 4 1709.8037 1.07 69086 17973 3 1709.802903 570.9418 40S ribosomal protein S15a OS=Homo sapiens OX=9606 GN=RPS15A PE=1 SV=2 4.72 3052.7 - 1.22E+06 - - - -0.4685 - 3.22 0.64 - 496.7 1 2 0 -0.0008 14 0 0 0 1.08E+08 1.01E+08 - - - 8.7828 1 221125_WJC_METTL3_EV_vs_WT_F05.17974.17974.3 4.13E-07 14/52 R.KAEVTLDGVWPTDK.T "sp|P52948|NUP98_HUMAN,tr|A0A3B3ITD8|A0A3B3ITD8_HUMAN" 2 1557.8039 0.69 69087 17974 3 1557.80557 520.2752 Nuclear pore complex protein Nup98-Nup96 OS=Homo sapiens OX=9606 GN=NUP98 PE=1 SV=4 4.56 3052.8 - 1.14E+06 - - - 1.0894 - 2.839 0.497 - 216 1 2 0 0.0017 14 0 0 0 2.13E+08 3.10E+08 - - - 6.8536 0.9999 221125_WJC_METTL3_EV_vs_WT_F05.17975.17975.3 7.18E-06 15/48 R.GYFEYIEENK[136.11]YSR[166.11].A "sp|Q00839|HNRPU_HUMAN,tr|Q5RI18|Q5RI18_HUMAN,tr|A0A1W2PP35|A0A1W2PP35_HUMAN,tr|A0A1W2PPS1|A0A1W2PPS1_HUMAN,tr|A0A1W2PRI6|A0A1W2PRI6_HUMAN" 5 1714.7958 1.71 69088 17975 3 1714.792511 572.6059 Heterogeneous nuclear ribonucleoprotein U OS=Homo sapiens OX=9606 GN=HNRNPU PE=1 SV=6 4.79 3052.9 - 1.12E+06 - - - -1.9017 - 2.84 0.578 - 253.5 1 2 1 -0.0033 13 0 0 0 1.50E+08 8.76E+07 - - - 7.8133 1 221125_WJC_METTL3_EV_vs_WT_F05.17977.17977.2 5.24E-07 15/24 K.LKDLFDYSPPLHK.N "sp|Q9NYF8|BCLF1_HUMAN,tr|E9PKI6|E9PKI6_HUMAN,tr|A0A1W2PQ43|A0A1W2PQ43_HUMAN,tr|E9PK91|E9PK91_HUMAN,tr|E9PK09|E9PK09_HUMAN,tr|E9PQN2|E9PQN2_HUMAN" 6 1571.8348 5.83 69090 17977 2 1571.834639 786.9247 Bcl-2-associated transcription factor 1 OS=Homo sapiens OX=9606 GN=BCLAF1 PE=1 SV=2 6.75 3053.1 - 590384 - - - -0.0897 - 3.23 0.595 - 569.2 1 2 1 -0.0001 13 0 0 0 2.20E+07 3.77E+06 - - - 6.4448 0.9414 221125_WJC_METTL3_EV_vs_WT_F05.17985.17985.3 0.0705 Aug-52 R.LK[136.11]QEFHYIEEDLYR[166.11].T sp|Q8TBA6|GOGA5_HUMAN 1 1899.9486 0.89 69096 17985 3 1899.955984 634.3235 Golgin subfamily A member 5 OS=Homo sapiens OX=9606 GN=GOLGA5 PE=1 SV=3 4.83 3054.2 - 582077 - - - 3.8948 - 1.557 0.285 - 72.3 1 2 1 0.0074 14 0 0 0 1.21E+07 1.36E+07 - - - 2.8921 0.9989 221125_WJC_METTL3_EV_vs_WT_F05.17988.17988.4 0.00308 Nov-72 K.LK[136.11]DLFDYSPPLHK[136.11].N "sp|Q9NYF8|BCLF1_HUMAN,tr|E9PKI6|E9PKI6_HUMAN,tr|A0A1W2PQ43|A0A1W2PQ43_HUMAN,tr|E9PK91|E9PK91_HUMAN,tr|E9PK09|E9PK09_HUMAN,tr|E9PQN2|E9PQN2_HUMAN" 6 1587.8632 2.6 69098 17988 4 1587.862166 397.9731 Bcl-2-associated transcription factor 1 OS=Homo sapiens OX=9606 GN=BCLAF1 PE=1 SV=2 6.75 3054.5 - 2.31E+07 - - - -0.6386 - 1.979 0.365 - 104.4 1 2 1 -0.001 13 0 0 0 9.84E+08 3.79E+08 - - - 2.6558 0.9702 221125_WJC_METTL3_EV_vs_WT_F05.17990.17990.2 4.53E-08 24-Oct K.HTDESLGDC[160.03]SFLN.T "sp|Q86U44|MTA70_HUMAN,tr|H0YFV6|H0YFV6_HUMAN" 2 1493.6093 - 69099 17990 2 1493.614026 747.8119 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 4.02 3054.7 - 1.89E+06 - - - 3.1822 - 2.397 0.541 - 225 1 1 0 0.0048 13 0 0 0 - - - - - 5.279 0.9981 221125_WJC_METTL3_EV_vs_WT_F05.17993.17993.3 0.00258 Sep-64 K.TFNIKNDFTEEEEAQVR.K "sp|P63208|SKP1_HUMAN,tr|E5RJR5|E5RJR5_HUMAN" 2 2068.9702 0.79 69102 17993 3 2068.971696 690.664 S-phase kinase-associated protein 1 OS=Homo sapiens OX=9606 GN=SKP1 PE=1 SV=2 4.25 3055.1 - 227466 - - - 0.7405 - 1.684 0.37 - 77.4 1 2 1 0.0015 17 0 0 0 2.10E+06 2.66E+06 - - - 3.9813 0.9999 221125_WJC_METTL3_EV_vs_WT_F05.17994.17994.3 2.75E-10 Oct-64 K.TFNIK[136.11]NDFTEEEEAQVR[166.11].K "sp|P63208|SKP1_HUMAN,tr|E5RJR5|E5RJR5_HUMAN" 2 2086.9926 0.77 69103 17994 3 2086.991732 696.6715 S-phase kinase-associated protein 1 OS=Homo sapiens OX=9606 GN=SKP1 PE=1 SV=2 4.25 3055.2 - 212437 - - - -0.4322 - 2.471 0.634 - 123 1 2 1 -0.0009 17 0 0 0 2.10E+06 2.72E+06 - - - 7.8936 0.9675 221125_WJC_METTL3_EV_vs_WT_F05.17996.17996.3 0.00936 Jun-52 R.GGRGGREFADFEYR[166.11].K "sp|Q8ND56|LS14A_HUMAN,tr|A0A140TA66|A0A140TA66_HUMAN,tr|A0A096LP11|A0A096LP11_HUMAN,tr|A0A0G2JQ95|A0A0G2JQ95_HUMAN" 4 1625.7574 - 69105 17996 3 1625.752187 542.9264 Protein LSM14 homolog A OS=Homo sapiens OX=9606 GN=LSM14A PE=1 SV=3 6.18 3055.5 - 204269 - - - -3.22 - 1.523 0.296 - 43.4 1 2 2 -0.0052 14 0 0 0 - - - - - 2.9566 0.9999 221125_WJC_METTL3_EV_vs_WT_F05.18000.18000.3 2.89E-05 20/60 K.YFLHDDRDDGVDYWAK.R "sp|Q9NYF8|BCLF1_HUMAN,tr|H0YF14|H0YF14_HUMAN" 2 2013.8857 2.16 69108 18000 3 2013.886126 672.3025 Bcl-2-associated transcription factor 1 OS=Homo sapiens OX=9606 GN=BCLAF1 PE=1 SV=2 4.28 3055.8 - 3.60E+06 - - - 0.2086 - 3.161 0.565 - 426.9 1 2 1 0.0004 16 0 0 0 5.39E+08 2.49E+08 - - - 7.7921 0.9996 221125_WJC_METTL3_EV_vs_WT_F05.18001.18001.3 0.00173 15/60 K.YFLHDDR[166.11]DDGVDYWAK[136.11].R "sp|Q9NYF8|BCLF1_HUMAN,tr|H0YF14|H0YF14_HUMAN" 2 2031.9082 2.16 69109 18001 3 2031.907993 678.31 Bcl-2-associated transcription factor 1 OS=Homo sapiens OX=9606 GN=BCLAF1 PE=1 SV=2 4.28 3055.9 - 2.03E+06 - - - -0.0901 - 2.236 0.425 - 195.2 1 2 1 -0.0002 16 0 0 0 5.39E+08 2.49E+08 - - - 5.343 1 221125_WJC_METTL3_EV_vs_WT_F05.18003.18003.4 2.14E-06 16/78 K.HGYIGEFEIIDDHR[166.11].A "sp|P62244|RS15A_HUMAN,tr|I3L246|I3L246_HUMAN,tr|I3L3P7|I3L3P7_HUMAN,tr|H3BN98|H3BN98_HUMAN" 4 1709.8037 0.95 69111 18003 4 1709.801372 428.4582 40S ribosomal protein S15a OS=Homo sapiens OX=9606 GN=RPS15A PE=1 SV=2 4.72 3056.1 - 315644 - - - -1.3639 - 2.837 0.517 - 254.6 1 2 0 -0.0023 14 0 0 0 8.56E+06 9.03E+06 - - - 4.1048 0.9997 221125_WJC_METTL3_EV_vs_WT_F05.18006.18006.3 1.02E-07 16/76 R.AIK[136.11]NDSVVAGGGAIEMELSK[136.11].Y sp|Q99832|TCPH_HUMAN 1 2004.0532 0.15 69112 18006 3 2004.052827 669.025 T-complex protein 1 subunit eta OS=Homo sapiens OX=9606 GN=CCT7 PE=1 SV=2 4.68 3056.5 - 646597 - - - -0.2071 - 3.274 0.38 - 349.8 1 2 1 -0.0004 20 0 0 0 6.18E+06 4.07E+07 - - - 5.6538 0.9995 221125_WJC_METTL3_EV_vs_WT_F05.18007.18007.3 3.47E-05 Dec-48 K.SK[136.11]LESELANFGPR[166.11].L "sp|Q14683|SMC1A_HUMAN,tr|G8JLG1|G8JLG1_HUMAN,tr|A0A6Q8PHC3|A0A6Q8PHC3_HUMAN" 3 1464.7692 1.13 69113 18007 3 1464.767665 489.2637 Structural maintenance of chromosomes protein 1A OS=Homo sapiens OX=9606 GN=SMC1A PE=1 SV=2 5.86 3056.6 - 541183 - - - -1.0227 - 2.324 0.383 - 272.2 1 2 1 -0.0015 13 0 0 0 3.09E+07 2.73E+07 - - - 5.0961 0.9975 221125_WJC_METTL3_EV_vs_WT_F05.18008.18008.4 0.566 Nov-90 K.NVTGHYISPFHDIPLK[136.11].V "sp|Q9H2U2|IPYR2_HUMAN,tr|D6RGV9|D6RGV9_HUMAN,tr|D6RAD3|D6RAD3_HUMAN,tr|D6R967|D6R967_HUMAN,tr|H0Y9D8|H0Y9D8_HUMAN,tr|A0A0C4DGB9|A0A0C4DGB9_HUMAN" 6 1844.9665 0.43 69114 18008 4 1844.965471 462.2489 "Inorganic pyrophosphatase 2, mitochondrial OS=Homo sapiens OX=9606 GN=PPA2 PE=1 SV=2" 6.92 3056.8 - 417243 - - - -0.5409 - 1.831 0.257 - 59.7 1 2 0 -0.001 16 0 0 0 3.21E+06 7.49E+06 - - - 1.6757 1 221125_WJC_METTL3_EV_vs_WT_F05.18010.18010.4 3.43E-06 14/78 K.HGYIGEFEIIDDHR.A "sp|P62244|RS15A_HUMAN,tr|I3L246|I3L246_HUMAN,tr|I3L3P7|I3L3P7_HUMAN,tr|H3BN98|H3BN98_HUMAN" 4 1699.7954 0.95 69116 18010 4 1699.793387 425.9561 40S ribosomal protein S15a OS=Homo sapiens OX=9606 GN=RPS15A PE=1 SV=2 4.72 3057 - 405893 - - - -1.2043 - 2.327 0.56 - 158.8 1 2 0 -0.002 14 0 0 0 8.52E+06 9.01E+06 - - - 4.4071 1 221125_WJC_METTL3_EV_vs_WT_F05.18011.18011.3 3.23E-09 16/64 K.GIRDDIEEEDDQEAYFR.Y "sp|Q86XP3|DDX42_HUMAN,tr|A0A0A0MSJ0|A0A0A0MSJ0_HUMAN,tr|J3KRE3|J3KRE3_HUMAN" 3 2098.908 1.57 69117 18011 3 2098.908756 700.6433 ATP-dependent RNA helicase DDX42 OS=Homo sapiens OX=9606 GN=DDX42 PE=1 SV=1 3.85 3057.2 - 402709 - - - 0.3807 - 3.614 0.669 - 455.8 1 2 1 0.0008 17 0 0 0 6.39E+06 4.06E+06 - - - 9.2443 0.9836 221125_WJC_METTL3_EV_vs_WT_F05.18013.18013.3 3.76E-05 Oct-48 K.SLTNDWEDHLAVK[136.11].H "sp|P08238|HS90B_HUMAN,sp|P07900|HS90A_HUMAN" 2 1534.7507 0.77 69119 18013 3 1535.747434 512.5909 Heat shock protein HSP 90-beta OS=Homo sapiens OX=9606 GN=HSP90AB1 PE=1 SV=4 4.53 3057.4 - 287576 - - - 649.4292 - 2.339 0.464 - 71 1 2 0 0.9967 13 0 0 0 6.69E+06 8.67E+06 - - - 5.7409 1 221125_WJC_METTL3_EV_vs_WT_F05.18019.18019.2 1.21E-08 14/24 R.GYFEYIEENKYSR.A "sp|Q00839|HNRPU_HUMAN,tr|Q5RI18|Q5RI18_HUMAN,tr|A0A1W2PP35|A0A1W2PP35_HUMAN,tr|A0A1W2PPS1|A0A1W2PPS1_HUMAN,tr|A0A1W2PRI6|A0A1W2PRI6_HUMAN" 5 1696.7733 0.69 69123 18019 2 1696.773325 849.3939 Heterogeneous nuclear ribonucleoprotein U OS=Homo sapiens OX=9606 GN=HNRNPU PE=1 SV=6 4.79 3058.1 - 471262 - - - 0.0136 - 2.955 0.673 - 787.9 1 2 1 0 13 0 0 0 6.95E+06 1.01E+07 - - - 6.7926 0.9991 221125_WJC_METTL3_EV_vs_WT_F05.18020.18020.3 1.52E-05 13/68 K.VKDGQLTVGLVGYPNVGK.S "sp|Q9H089|LSG1_HUMAN,tr|H7C2X7|H7C2X7_HUMAN" 2 1843.0203 0.89 69124 18020 3 1843.02196 615.3474 Large subunit GTPase 1 homolog OS=Homo sapiens OX=9606 GN=LSG1 PE=1 SV=2 8.47 3058.2 - 645487 - - - 0.8741 - 2.35 0.352 - 146.1 1 2 1 0.0016 18 0 0 0 6.63E+06 7.48E+06 - - - 4.5916 1 221125_WJC_METTL3_EV_vs_WT_F05.18021.18021.2 1.25E-09 17/26 R.KAEVTLDGVWPTDK.T "sp|P52948|NUP98_HUMAN,tr|A0A3B3ITD8|A0A3B3ITD8_HUMAN" 2 1557.8039 1.42 69125 18021 2 1557.807049 779.9092 Nuclear pore complex protein Nup98-Nup96 OS=Homo sapiens OX=9606 GN=NUP98 PE=1 SV=4 4.56 3058.4 - 488468 - - - 2.0388 - 3.898 0.557 - 717.3 1 2 0 0.0032 14 0 0 0 2.19E+07 1.54E+07 - - - 6.568 0.9835 221125_WJC_METTL3_EV_vs_WT_F05.18023.18023.4 0.188 Nov-72 R.LKSELHLLDFQGK.Q sp|Q9Y3A2|UTP11_HUMAN 1 1526.8457 1.75 69127 18023 4 1526.843878 382.7187 Probable U3 small nucleolar RNA-associated protein 11 OS=Homo sapiens OX=9606 GN=UTP11 PE=1 SV=2 6.75 3058.6 - 261730 - - - -1.1796 - 1.73 0.236 - 64 1 2 1 -0.0018 13 0 0 0 5.68E+06 3.24E+06 - - - 1.4829 0.9995 221125_WJC_METTL3_EV_vs_WT_F05.18024.18024.3 0.00177 Aug-76 R.VNSASSSNPPAEVDPDTILK.A "sp|Q9BY77|PDIP3_HUMAN,tr|F6VRR5|F6VRR5_HUMAN" 2 2040.0011 1.31 69128 18024 3 2040.001243 681.0077 Polymerase delta-interacting protein 3 OS=Homo sapiens OX=9606 GN=POLDIP3 PE=1 SV=2 4.03 3058.8 - 216908 - - - 0.0559 - 1.773 0.347 - 35.6 1 2 0 0.0001 20 0 0 0 2.32E+06 1.77E+06 - - - 3.798 0.9986 221125_WJC_METTL3_EV_vs_WT_F05.18027.18027.3 0.000148 16/60 K.TGEEIFGTIGMRPNAK.N "sp|Q99873|ANM1_HUMAN,tr|E9PKG1|E9PKG1_HUMAN" 2 1719.8614 1.9 69129 18027 3 1720.868171 574.2944 Protein arginine N-methyltransferase 1 OS=Homo sapiens OX=9606 GN=PRMT1 PE=1 SV=3 5.81 3059.2 - 2.08E+06 - - - 585.3762 - 3.109 0.498 - 344.2 1 2 0 1.0068 16 0 0 0 1.09E+08 5.75E+07 - - - 6.7238 0.998 221125_WJC_METTL3_EV_vs_WT_F05.18028.18028.3 0.00075 Oct-48 K.SKLESELANFGPR.L "sp|Q14683|SMC1A_HUMAN,tr|G8JLG1|G8JLG1_HUMAN,tr|A0A6Q8PHC3|A0A6Q8PHC3_HUMAN" 3 1446.7467 1.12 69130 18028 3 1446.746603 483.2562 Structural maintenance of chromosomes protein 1A OS=Homo sapiens OX=9606 GN=SMC1A PE=1 SV=2 5.86 3059.3 - 1.22E+06 - - - -0.0622 - 1.72 0.351 - 101.8 1 2 1 -0.0001 13 0 0 0 3.02E+07 2.69E+07 - - - 3.9237 0.9996 221125_WJC_METTL3_EV_vs_WT_F05.18029.18029.3 1.87E-08 18/68 K.VK[136.11]DGQLTVGLVGYPNVGK[136.11].S "sp|Q9H089|LSG1_HUMAN,tr|H7C2X7|H7C2X7_HUMAN" 2 1859.0487 0.89 69131 18029 3 1859.048133 620.6902 Large subunit GTPase 1 homolog OS=Homo sapiens OX=9606 GN=LSG1 PE=1 SV=2 8.47 3059.4 - 725680 - - - -0.3314 - 2.909 0.379 - 352.9 1 2 1 -0.0006 18 0 0 0 6.63E+06 7.48E+06 - - - 5.4243 0.9997 221125_WJC_METTL3_EV_vs_WT_F05.18030.18030.3 4.06E-05 13/52 R.LKQEFHYIEEDLYR.T sp|Q8TBA6|GOGA5_HUMAN 1 1881.9261 0.89 69132 18030 3 1881.922903 628.316 Golgin subfamily A member 5 OS=Homo sapiens OX=9606 GN=GOLGA5 PE=1 SV=3 4.83 3059.5 - 661007 - - - -1.7062 - 2.662 0.447 - 239 1 2 1 -0.0032 14 0 0 0 1.21E+07 1.36E+07 - - - 6.1247 1 221125_WJC_METTL3_EV_vs_WT_F05.18031.18031.3 1.83E-06 18/80 K.AENNSEVGASGYGVPGPTWDR[166.11].G sp|Q08211|DHX9_HUMAN 1 2171.9747 1.12 69133 18031 3 2171.976901 724.9989 ATP-dependent RNA helicase A OS=Homo sapiens OX=9606 GN=DHX9 PE=1 SV=4 4.14 3059.7 - 652513 - - - 0.9926 - 2.477 0.563 - 171 1 2 0 0.0022 21 0 0 0 4.40E+07 3.91E+07 - - - 6.9909 1 221125_WJC_METTL3_EV_vs_WT_F05.18032.18032.3 2.79E-08 18/80 R.MFDYTDDPEGPVMPGSHSVER.F sp|Q09161|NCBP1_HUMAN 1 2364.9991 1.15 69134 18032 3 2364.995405 789.3403 Nuclear cap-binding protein subunit 1 OS=Homo sapiens OX=9606 GN=NCBP1 PE=1 SV=1 4.1 3059.8 - 595181 - - - -1.5611 - 3.084 0.654 - 257.6 1 2 0 -0.0037 21 0 0 0 5.41E+06 4.69E+06 - - - 8.5305 0.9991 221125_WJC_METTL3_EV_vs_WT_F05.18033.18033.2 4.68E-09 24-Nov R.GYFEYIEENK[136.11]YSR[166.11].A "sp|Q00839|HNRPU_HUMAN,tr|Q5RI18|Q5RI18_HUMAN,tr|A0A1W2PP35|A0A1W2PP35_HUMAN,tr|A0A1W2PPS1|A0A1W2PPS1_HUMAN,tr|A0A1W2PRI6|A0A1W2PRI6_HUMAN" 5 1714.7958 0.69 69135 18033 2 1714.795845 858.4052 Heterogeneous nuclear ribonucleoprotein U OS=Homo sapiens OX=9606 GN=HNRNPU PE=1 SV=6 4.79 3059.9 - 490646 - - - 0.0426 - 2.616 0.558 - 433.7 1 2 1 0.0001 13 0 0 0 6.95E+06 1.01E+07 - - - 5.6305 1 221125_WJC_METTL3_EV_vs_WT_F05.18034.18034.3 1.51E-11 13/64 K.GIR[166.11]DDIEEEDDQEAYFR[166.11].Y "sp|Q86XP3|DDX42_HUMAN,tr|A0A0A0MSJ0|A0A0A0MSJ0_HUMAN,tr|J3KRE3|J3KRE3_HUMAN" 3 2118.9245 1.57 69136 18034 3 2118.922634 707.3154 ATP-dependent RNA helicase DDX42 OS=Homo sapiens OX=9606 GN=DDX42 PE=1 SV=1 3.85 3060.1 - 358161 - - - -0.8792 - 3.319 0.701 - 268.9 1 2 1 -0.0019 17 0 0 0 6.39E+06 4.06E+06 - - - 9.3857 0.9999 221125_WJC_METTL3_EV_vs_WT_F05.18038.18038.3 1.79E-05 14/48 K.LKDLFDYSPPLHK.N "sp|Q9NYF8|BCLF1_HUMAN,tr|E9PKI6|E9PKI6_HUMAN,tr|A0A1W2PQ43|A0A1W2PQ43_HUMAN,tr|E9PK91|E9PK91_HUMAN,tr|E9PK09|E9PK09_HUMAN,tr|E9PQN2|E9PQN2_HUMAN" 6 1571.8348 3.06 69139 18038 3 1571.833923 524.9522 Bcl-2-associated transcription factor 1 OS=Homo sapiens OX=9606 GN=BCLAF1 PE=1 SV=2 6.75 3060.6 - 1.43E+07 - - - -0.5452 - 2.852 0.545 - 262.8 1 2 1 -0.0009 13 0 0 0 5.53E+08 1.81E+08 - - - 7.4575 1 221125_WJC_METTL3_EV_vs_WT_F05.18041.18041.3 2.51E-08 21/56 Y.FLHDDRDDGVDYWAK.R "sp|Q9NYF8|BCLF1_HUMAN,tr|H0YF14|H0YF14_HUMAN" 2 1850.8224 2.59 69142 18041 3 1850.819223 617.9481 Bcl-2-associated transcription factor 1 OS=Homo sapiens OX=9606 GN=BCLAF1 PE=1 SV=2 4.28 3060.9 - 911710 - - - -1.7041 - 3.115 0.637 - 520.5 1 1 1 -0.0032 15 0 0 0 1.45E+07 5.58E+06 - - - 8.6059 1 221125_WJC_METTL3_EV_vs_WT_F05.18042.18042.3 1.49E-09 24/84 K.VIAINVDDPDAANYNDINDVK[136.11]R[166.11].L sp|Q15181|IPYR_HUMAN 1 2461.2204 0.61 69143 18042 3 2461.216666 821.4141 Inorganic pyrophosphatase OS=Homo sapiens OX=9606 GN=PPA1 PE=1 SV=2 3.97 3061 - 871236 - - - -1.5179 - 4.17 0.692 - 714 1 2 0 -0.0037 22 0 0 0 2.75E+07 4.49E+07 - - - 9.6394 0.9998 221125_WJC_METTL3_EV_vs_WT_F05.18044.18044.2 0.000419 14-Jul R.EFADFEYR.K "sp|Q8ND56|LS14A_HUMAN,tr|A0A140TA66|A0A140TA66_HUMAN,tr|A0A096LP11|A0A096LP11_HUMAN,tr|A0A0G2JQ95|A0A0G2JQ95_HUMAN" 4 1075.4611 1.21 69145 18044 2 1075.46081 538.7378 Protein LSM14 homolog A OS=Homo sapiens OX=9606 GN=LSM14A PE=1 SV=3 4.14 3061.3 - 396210 - - - -0.2464 - 1.644 0.527 - 208.3 1 2 0 -0.0003 8 0 0 0 4.26E+06 3.52E+06 - - - 4.4327 1 221125_WJC_METTL3_EV_vs_WT_F05.18045.18045.2 2.95E-08 30-Oct K.YFLHDDR[166.11]DDGVDYWAK[136.11].R "sp|Q9NYF8|BCLF1_HUMAN,tr|H0YF14|H0YF14_HUMAN" 2 2031.9082 2.49 69146 18045 2 2031.906643 1016.9614 Bcl-2-associated transcription factor 1 OS=Homo sapiens OX=9606 GN=BCLAF1 PE=1 SV=2 4.28 3061.4 - 339953 - - - -0.7545 - 2.319 0.644 - 245.1 1 2 1 -0.0015 16 0 0 0 1.34E+07 5.38E+06 - - - 5.8651 1 221125_WJC_METTL3_EV_vs_WT_F05.18050.18050.3 4.58E-09 16/60 K.TGEEIFGTIGMR[166.11]PNAK[136.11].N "sp|Q99873|ANM1_HUMAN,tr|E9PKG1|E9PKG1_HUMAN" 2 1737.8839 1.87 69149 18050 3 1737.88307 580.3019 Protein arginine N-methyltransferase 1 OS=Homo sapiens OX=9606 GN=PRMT1 PE=1 SV=3 5.81 3062 - 2.76E+06 - - - -0.4632 - 3.196 0.6 - 422.2 1 2 0 -0.0008 16 0 0 0 1.09E+08 5.84E+07 - - - 8.2105 1 221125_WJC_METTL3_EV_vs_WT_F05.18051.18051.3 1.37E-09 21/80 K.AENNSEVGASGYGVPGPTWDR.G sp|Q08211|DHX9_HUMAN 1 2161.9665 1.12 69150 18051 3 2161.964316 721.6628 ATP-dependent RNA helicase A OS=Homo sapiens OX=9606 GN=DHX9 PE=1 SV=4 4.14 3062.1 - 1.92E+06 - - - -0.9986 - 3.454 0.624 - 278.6 1 2 0 -0.0022 21 0 0 0 4.40E+07 3.92E+07 - - - 8.4681 1 221125_WJC_METTL3_EV_vs_WT_F05.18052.18052.3 3.71E-11 24/80 K.YAGVFAENAEDADGKDVFNTK.S sp|Q96EU7|C1GLC_HUMAN 1 2260.0284 1.23 69151 18052 3 2260.023983 754.3501 C1GALT1-specific chaperone 1 OS=Homo sapiens OX=9606 GN=C1GALT1C1 PE=1 SV=1 4.11 3062.2 - 1.26E+06 - - - -1.9575 - 4.889 0.727 - 662.1 1 2 1 -0.0044 21 0 0 0 1.45E+07 1.18E+07 - - - 10.4488 1 221125_WJC_METTL3_EV_vs_WT_F05.18053.18053.2 6.03E-09 20/30 K.YFLHDDRDDGVDYWAK.R "sp|Q9NYF8|BCLF1_HUMAN,tr|H0YF14|H0YF14_HUMAN" 2 2013.8857 2.49 69152 18053 2 2013.883941 1007.9501 Bcl-2-associated transcription factor 1 OS=Homo sapiens OX=9606 GN=BCLAF1 PE=1 SV=2 4.28 3062.3 - 959956 - - - -0.8764 - 2.99 0.75 - 1066.4 1 2 1 -0.0018 16 0 0 0 1.34E+07 5.38E+06 - - - 7.2727 1 221125_WJC_METTL3_EV_vs_WT_F05.18054.18054.3 9.21E-11 23/108 R.GFGDGYNGYGGGPGGGNFGGSPGYGGGR[166.11].G "sp|P22626|ROA2_HUMAN,tr|A0A024RA28|A0A024RA28_HUMAN,tr|A0A7I2V323|A0A7I2V323_HUMAN,tr|A0A7I2V3P7|A0A7I2V3P7_HUMAN" 4 2504.0405 1.57 69153 18054 3 2504.03608 835.6875 Heterogeneous nuclear ribonucleoproteins A2\B1 OS=Homo sapiens OX=9606 GN=HNRNPA2B1 PE=1 SV=2 5.83 3062.4 - 833863 - - - -1.7783 - 3.879 0.684 - 380.6 1 2 0 -0.0045 28 0 0 0 2.21E+07 1.41E+07 - - - 9.2834 0.9971 221125_WJC_METTL3_EV_vs_WT_F05.18055.18055.3 0.00886 Sep-60 K.SGWGELSASTEWKDPK.N "sp|Q9UPQ9|TNR6B_HUMAN,tr|H0Y720|H0Y720_HUMAN" 2 1776.8319 3.61 69154 18055 3 1776.833638 593.2846 Trinucleotide repeat-containing gene 6B protein OS=Homo sapiens OX=9606 GN=TNRC6B PE=1 SV=4 4.68 3062.5 - 810710 - - - 0.99 - 1.612 0.354 - 51.4 1 2 1 0.0018 16 0 0 0 1.20E+07 3.31E+06 - - - 3.7114 0.9995 221125_WJC_METTL3_EV_vs_WT_F05.18056.18056.3 0.0113 Aug-44 R.NGENGIHFLLNR[166.11].D "sp|Q12849|GRSF1_HUMAN,tr|H0YAK1|H0YAK1_HUMAN,tr|H0Y8R1|H0Y8R1_HUMAN,tr|F5H5I6|F5H5I6_HUMAN" 4 1392.7138 2.89 69155 18056 3 1392.715241 465.2452 G-rich sequence factor 1 OS=Homo sapiens OX=9606 GN=GRSF1 PE=1 SV=3 6.75 3062.7 - 100634 - - - 1.0584 - 1.57 0.368 - 86.3 1 2 0 0.0015 12 0 0 0 1.79E+06 6.19E+05 - - - 3.8927 1 221125_WJC_METTL3_EV_vs_WT_F05.18059.18059.3 2.16E-15 23/108 R.GFGDGYNGYGGGPGGGNFGGSPGYGGGR.G "sp|P22626|ROA2_HUMAN,tr|A0A024RA28|A0A024RA28_HUMAN,tr|A0A7I2V323|A0A7I2V323_HUMAN,tr|A0A7I2V3P7|A0A7I2V3P7_HUMAN" 4 2494.0323 1.57 69156 18059 3 2494.030815 832.3514 Heterogeneous nuclear ribonucleoproteins A2\B1 OS=Homo sapiens OX=9606 GN=HNRNPA2B1 PE=1 SV=2 5.83 3063.1 - 1.27E+06 - - - -0.5806 - 4.1 0.754 - 321.9 1 2 0 -0.0014 28 0 0 0 2.21E+07 1.41E+07 - - - 10.1921 1 221125_WJC_METTL3_EV_vs_WT_F05.18060.18060.3 2.55E-11 24/84 K.VIAINVDDPDAANYNDINDVKR.L sp|Q15181|IPYR_HUMAN 1 2443.1979 0.61 69157 18060 3 2443.195784 815.4066 Inorganic pyrophosphatase OS=Homo sapiens OX=9606 GN=PPA1 PE=1 SV=2 3.97 3063.2 - 1.45E+06 - - - -0.8792 - 4.335 0.688 - 673 1 2 0 -0.0021 22 0 0 0 2.75E+07 4.49E+07 - - - 9.6873 1 221125_WJC_METTL3_EV_vs_WT_F05.18063.18063.2 2.44E-16 22/40 K.AENNSEVGASGYGVPGPTWDR.G sp|Q08211|DHX9_HUMAN 1 2161.9665 1.1 69160 18063 2 2161.963516 1081.9905 ATP-dependent RNA helicase A OS=Homo sapiens OX=9606 GN=DHX9 PE=1 SV=4 4.14 3063.6 - 840535 - - - -1.3687 - 4.125 0.765 - 864.5 1 2 0 -0.003 21 0 0 0 1.73E+07 1.57E+07 - - - 8.1743 1 221125_WJC_METTL3_EV_vs_WT_F05.18065.18065.2 2.85E-13 21/40 K.AENNSEVGASGYGVPGPTWDR[166.11].G sp|Q08211|DHX9_HUMAN 1 2171.9747 1.1 69162 18065 2 2171.975461 1086.9946 ATP-dependent RNA helicase A OS=Homo sapiens OX=9606 GN=DHX9 PE=1 SV=4 4.14 3063.8 - 738386 - - - 0.3297 - 3.829 0.769 - 673.3 1 2 0 0.0007 21 0 0 0 1.73E+07 1.57E+07 - - - 8.0215 1 221125_WJC_METTL3_EV_vs_WT_F05.18066.18066.3 3.33E-10 18/88 K.VLSVC[160.03]PSNKPAIVEAGGMQALGK.H sp|P14923|PLAK_HUMAN 1 2325.2185 11.49 69163 18066 3 2325.215666 776.0801 Junction plakoglobin OS=Homo sapiens OX=9606 GN=JUP PE=1 SV=3 8.17 3064 - 684837 - - - -1.2072 - 3.309 0.634 - 374.3 1 2 0 -0.0028 23 0 0 0 7.00E+06 6.09E+05 - - - 8.415 0.9999 221125_WJC_METTL3_EV_vs_WT_F05.18067.18067.3 8.37E-05 14/68 K.SIEIPR[166.11]PVDGVEVPGC[160.03]GK[136.11].L "sp|P26368|U2AF2_HUMAN,tr|K7ENG2|K7ENG2_HUMAN" 2 1926 1.2 69164 18067 3 1925.996174 643.0073 Splicing factor U2AF 65 kDa subunit OS=Homo sapiens OX=9606 GN=U2AF2 PE=1 SV=4 4.68 3064.1 - 677174 - - - -1.9699 - 2.616 0.487 - 136.8 1 2 0 -0.0038 18 0 0 0 5.25E+07 4.37E+07 - - - 6.3631 0.9981 221125_WJC_METTL3_EV_vs_WT_F05.18068.18068.3 0.0215 Nov-76 K.NPAVQAGSIVVLQGGEETQR.Y "sp|P12955|PEPD_HUMAN,tr|A0A494C194|A0A494C194_HUMAN,tr|K7ES25|K7ES25_HUMAN,tr|A0A494C165|A0A494C165_HUMAN" 4 2052.06 4.76 69165 18068 3 2052.057603 685.0273 Xaa-Pro dipeptidase OS=Homo sapiens OX=9606 GN=PEPD PE=1 SV=3 4.53 3064.2 - 344659 - - - -1.1593 - 1.827 0.26 - 85.5 1 2 0 -0.0024 20 0 0 0 4.45E+06 9.33E+05 - - - 2.9002 1 221125_WJC_METTL3_EV_vs_WT_F05.18071.18071.3 4.94E-08 15/48 R.ANEKEPC[160.03]C[160.03]WWLAK.V "sp|Q06787|FMR1_HUMAN,tr|R9WNI0|R9WNI0_HUMAN,tr|A8MQB8|A8MQB8_HUMAN,tr|A0A087WXI3|A0A087WXI3_HUMAN,tr|Q8IXW7|Q8IXW7_HUMAN,tr|G3V0J0|G3V0J0_HUMAN" 6 1690.7596 0.57 69166 18071 3 1690.759123 564.5938 Synaptic functional regulator FMR1 OS=Homo sapiens OX=9606 GN=FMR1 PE=1 SV=1 6.17 3064.6 - 2.56E+06 - - - -0.2721 - 2.874 0.631 - 357.6 1 2 1 -0.0005 13 0 0 0 6.09E+07 1.08E+08 - - - 8.4372 1 221125_WJC_METTL3_EV_vs_WT_F05.18073.18073.3 6.63E-08 16/68 K.K[136.11]GVNLPGAAVDLPAVSEK[136.11].D "sp|P14618|KPYM_HUMAN,tr|H3BQ34|H3BQ34_HUMAN,tr|B4DNK4|B4DNK4_HUMAN,tr|A0A804F6T5|A0A804F6T5_HUMAN,tr|H3BTN5|H3BTN5_HUMAN,tr|H3BR70|H3BR70_HUMAN,tr|A0A804F729|A0A804F729_HUMAN" 7 1780.0065 2.05 69168 18073 3 1780.007328 594.3428 Pyruvate kinase PKM OS=Homo sapiens OX=9606 GN=PKM PE=1 SV=4 6.07 3064.9 - 824680 - - - 0.4376 - 3.018 0.626 - 292.7 1 2 0 0.0008 18 0 0 0 7.95E+07 3.88E+07 - - - 8.2696 1 221125_WJC_METTL3_EV_vs_WT_F05.18075.18075.3 3.06E-07 15/68 K.SIEIPRPVDGVEVPGC[160.03]GK.L "sp|P26368|U2AF2_HUMAN,tr|K7ENG2|K7ENG2_HUMAN" 2 1907.9775 0.96 69170 18075 3 1907.977675 636.9998 Splicing factor U2AF 65 kDa subunit OS=Homo sapiens OX=9606 GN=U2AF2 PE=1 SV=4 4.68 3065.1 - 798074 - - - 0.0928 - 2.666 0.567 - 179.1 1 2 0 0.0002 18 0 0 0 4.11E+07 4.30E+07 - - - 7.3032 1 221125_WJC_METTL3_EV_vs_WT_F05.18076.18076.4 1.29E-10 21/126 R.NIDNPALADIYTEHAHQVVVAK.Y "sp|O75083|WDR1_HUMAN,tr|D6RD66|D6RD66_HUMAN" 2 2417.2339 1.87 69171 18076 4 2417.234198 605.3158 WD repeat-containing protein 1 OS=Homo sapiens OX=9606 GN=WDR1 PE=1 SV=4 5.21 3065.2 - 679364 - - - 0.1138 - 3.957 0.655 - 269.2 1 2 0 0.0003 22 0 0 0 8.01E+06 4.29E+06 - - - 5.3771 1 221125_WJC_METTL3_EV_vs_WT_F05.18078.18078.2 1.58E-11 15/28 R.EADSSSDYVNMDFTK.R "sp|O14654|IRS4_HUMAN,tr|A0A804CF45|A0A804CF45_HUMAN" 2 1707.6934 1.08 69173 18078 2 1707.692824 854.854 Insulin receptor substrate 4 OS=Homo sapiens OX=9606 GN=IRS4 PE=1 SV=1 3.84 3065.5 - 374858 - - - -0.335 - 3.284 0.769 - 989.6 1 2 0 -0.0006 15 0 0 0 2.64E+07 2.45E+07 - - - 7.644 0.9968 221125_WJC_METTL3_EV_vs_WT_F05.18081.18081.2 5.57E-06 24-Nov K.SK[136.11]LESELANFGPR[166.11].L "sp|Q14683|SMC1A_HUMAN,tr|G8JLG1|G8JLG1_HUMAN,tr|A0A6Q8PHC3|A0A6Q8PHC3_HUMAN" 3 1464.7692 0.75 69176 18081 2 1464.767333 733.3919 Structural maintenance of chromosomes protein 1A OS=Homo sapiens OX=9606 GN=SMC1A PE=1 SV=2 5.86 3065.9 - 229358 - - - -1.2493 - 2.298 0.383 - 332.8 1 2 1 -0.0018 13 0 0 0 2.41E+06 3.19E+06 - - - 4.0047 1 221125_WJC_METTL3_EV_vs_WT_F05.18084.18084.3 1.29E-11 17/68 K.LHDETLTYLNQGQSYEIR[166.11].M "sp|Q9NZI7|UBIP1_HUMAN,sp|Q12800|TFCP2_HUMAN,tr|C9JWL3|C9JWL3_HUMAN,tr|F8VX55|F8VX55_HUMAN" 4 2189.0628 0.62 69177 18084 3 2189.064982 730.6949 Upstream-binding protein 1 OS=Homo sapiens OX=9606 GN=UBP1 PE=1 SV=1 4.65 3066.3 - 746887 - - - 0.9822 - 3.565 0.595 - 355.2 1 2 0 0.0022 18 0 0 0 4.53E+06 7.34E+06 - - - 8.3384 1 221125_WJC_METTL3_EV_vs_WT_F05.18085.18085.3 1.15E-12 26/56 K.HLEINPDHSIIETLR[166.11].Q sp|P07900|HS90A_HUMAN 1 1795.9456 0.64 69178 18085 3 1795.946806 599.6558 Heat shock protein HSP 90-alpha OS=Homo sapiens OX=9606 GN=HSP90AA1 PE=1 SV=5 5.27 3066.4 - 954493 - - - 0.662 - 4.504 0.668 - 1276.2 1 2 0 0.0012 15 0 0 0 6.06E+07 9.45E+07 - - - 9.9142 0.9363 221125_WJC_METTL3_EV_vs_WT_F05.18086.18086.2 0.0367 28-Sep R.SSGGSGGGPLSHFYS.G "tr|K7EQG2|K7EQG2_HUMAN,tr|E9PAU2|E9PAU2_HUMAN,tr|A0A087WZ13|A0A087WZ13_HUMAN" 3 1395.6055 - 69179 18086 2 1395.604269 698.81 Uncharacterized protein (Fragment) OS=Homo sapiens OX=9606 PE=1 SV=1 6.46 3066.5 - 356739 - - - -0.8878 - 1.528 0.311 - 154.6 1 1 0 -0.0012 15 0 0 0 - - - - - 2.38 1 221125_WJC_METTL3_EV_vs_WT_F05.18089.18089.4 1.07E-07 16/84 K.HLEINPDHSIIETLR[166.11].Q sp|P07900|HS90A_HUMAN 1 1795.9456 0.68 69180 18089 4 1795.945029 449.9937 Heat shock protein HSP 90-alpha OS=Homo sapiens OX=9606 GN=HSP90AA1 PE=1 SV=5 5.27 3066.9 - 474112 - - - -0.3274 - 3.117 0.497 - 279.8 1 2 0 -0.0006 15 0 0 0 1.59E+07 2.35E+07 - - - 3.9585 0.9996 221125_WJC_METTL3_EV_vs_WT_F05.18090.18090.3 0.103 Nov-36 K.STFVLDEFKR.K sp|P26641|EF1G_HUMAN 1 1240.6452 0.83 69181 18090 3 1240.645409 414.5557 Elongation factor 1-gamma OS=Homo sapiens OX=9606 GN=EEF1G PE=1 SV=3 5.79 3067.1 - 201877 - - - 0.1781 - 2.07 0.299 - 191.5 1 2 0 0.0002 10 0 0 0 2.54E+06 3.06E+06 - - - 3.9983 1 221125_WJC_METTL3_EV_vs_WT_F05.18091.18091.3 1.83E-06 13/52 K.HWPFMVVNDAGR[166.11]PK[136.11].V "sp|P11142|HSP7C_HUMAN,tr|E9PQQ4|E9PQQ4_HUMAN,tr|E9PNE6|E9PNE6_HUMAN,tr|E9PKE3|E9PKE3_HUMAN,tr|E9PN89|E9PN89_HUMAN,tr|E9PLF4|E9PLF4_HUMAN,tr|E9PK54|E9PK54_HUMAN,tr|E9PN25|E9PN25_HUMAN,tr|E9PPY6|E9PPY6_HUMAN,tr|E9PQK7|E9PQK7_HUMAN" 10 1670.847 0.11 69182 18091 3 1670.849129 557.9563 Heat shock cognate 71 kDa protein OS=Homo sapiens OX=9606 GN=HSPA8 PE=1 SV=1 8.75 3067.2 - 410223 - - - 1.2527 - 2.538 0.533 - 242.5 1 2 0 0.0021 14 0 0 0 2.53E+06 2.39E+07 - - - 6.957 0.9999 221125_WJC_METTL3_EV_vs_WT_F05.18095.18095.3 0.0409 Nov-44 K.WIGLDLSNGKPR.D "sp|P17987|TCPA_HUMAN,tr|F5H282|F5H282_HUMAN,tr|E7EQR6|E7EQR6_HUMAN" 3 1354.7357 0.43 69186 18095 3 1354.736163 452.5859 T-complex protein 1 subunit alpha OS=Homo sapiens OX=9606 GN=TCP1 PE=1 SV=1 8.75 3067.7 - 249254 - - - 0.3167 - 2.344 0.365 - 212.5 1 2 0 0.0004 12 0 0 0 6.15E+06 1.42E+07 - - - 4.9705 0.9997 221125_WJC_METTL3_EV_vs_WT_F05.18096.18096.4 8.21E-06 Dec-72 K.NFDVGHVPIRLPR.T "sp|P50579|MAP2_HUMAN,tr|F8VQZ7|F8VQZ7_HUMAN,tr|F8VRR3|F8VRR3_HUMAN" 3 1518.8419 0.24 69187 18096 4 1518.843144 380.7178 Methionine aminopeptidase 2 OS=Homo sapiens OX=9606 GN=METAP2 PE=1 SV=1 9.61 3067.8 - 167216 - - - 0.7986 - 2.442 0.436 - 183 1 2 1 0.0012 13 0 0 0 1.76E+06 7.19E+06 - - - 3.3516 1 221125_WJC_METTL3_EV_vs_WT_F05.18099.18099.3 4.96E-07 14/72 K.SIQTPQSHGTLTAELWDNK[136.11].V "sp|Q9Y520|PRC2C_HUMAN,tr|E7EPN9|E7EPN9_HUMAN,tr|H7C5N8|H7C5N8_HUMAN,tr|A0A2R8Y7F4|A0A2R8Y7F4_HUMAN,tr|A0A2R8YET2|A0A2R8YET2_HUMAN" 5 2133.0582 0.39 69188 18099 3 2133.058797 712.0267 Protein PRRC2C OS=Homo sapiens OX=9606 GN=PRRC2C PE=1 SV=4 5.3 3068.2 - 293660 - - - 0.2813 - 2.698 0.529 - 111.8 1 2 0 0.0006 19 0 0 0 1.02E+07 2.65E+07 - - - 6.8761 0.9994 221125_WJC_METTL3_EV_vs_WT_F05.18101.18101.4 5.50E-06 14/96 K.TQLIAHDKEVYDIAFSR.A "sp|P61962|DCAF7_HUMAN,tr|A0A087WWI6|A0A087WWI6_HUMAN" 2 2005.0269 1.42 69190 18101 4 2005.030338 502.264 DDB1- and CUL4-associated factor 7 OS=Homo sapiens OX=9606 GN=DCAF7 PE=1 SV=1 5.35 3068.5 - 647876 - - - 1.7192 - 2.489 0.414 - 141.7 1 2 1 0.0034 17 0 0 0 3.97E+07 2.80E+07 - - - 3.1451 0.9998 221125_WJC_METTL3_EV_vs_WT_F05.18102.18102.3 0.0712 13/76 R.ILSAENIPNLPPGGGLAGKR.N "sp|O75688|PPM1B_HUMAN,tr|B8ZZF0|B8ZZF0_HUMAN,tr|A0A3B3IS24|A0A3B3IS24_HUMAN,tr|C9JIR6|C9JIR6_HUMAN" 4 1973.1058 4.36 69191 18102 3 1973.10914 658.7092 Protein phosphatase 1B OS=Homo sapiens OX=9606 GN=PPM1B PE=1 SV=1 8.75 3068.6 - 456105 - - - 1.6877 - 2.861 0.365 - 154.7 1 2 0 0.0033 20 0 0 0 5.07E+06 1.16E+06 - - - 5.1586 1 221125_WJC_METTL3_EV_vs_WT_F05.18103.18103.4 4.64E-11 19/84 K.HLEINPDHSIIETLR.Q sp|P07900|HS90A_HUMAN 1 1785.9373 0.68 69192 18103 4 1785.94032 447.4916 Heat shock protein HSP 90-alpha OS=Homo sapiens OX=9606 GN=HSP90AA1 PE=1 SV=5 5.27 3068.7 - 413019 - - - 1.6647 - 2.979 0.621 - 422.3 1 2 0 0.003 15 0 0 0 1.59E+07 2.35E+07 - - - 5.0209 0.9789 221125_WJC_METTL3_EV_vs_WT_F05.18104.18104.3 1.62E-05 14/52 R.AESLQQEVEALKER.V "sp|Q14203|DCTN1_HUMAN,tr|A0A804CDA6|A0A804CDA6_HUMAN,tr|E7EX90|E7EX90_HUMAN,tr|A0A7P0Z4C3|A0A7P0Z4C3_HUMAN,tr|Q6AWB1|Q6AWB1_HUMAN" 5 1628.837 2.03 69193 18104 3 1628.833175 543.9529 Dynactin subunit 1 OS=Homo sapiens OX=9606 GN=DCTN1 PE=1 SV=3 4.49 3068.9 - 401247 - - - -2.3262 - 2.459 0.169 - 173.3 1 2 1 -0.0038 14 0 0 0 1.16E+08 5.73E+07 - - - 2.8143 1 221125_WJC_METTL3_EV_vs_WT_F05.18106.18106.2 4.46E-06 14/28 L.TTEIDNNIEQISSYK.S "sp|P13645|K1C10_HUMAN,tr|A0A1B0GVI3|A0A1B0GVI3_HUMAN" 2 1753.837 999 69195 18106 2 1753.838712 877.9258 "Keratin, type I cytoskeletal 10 OS=Homo sapiens OX=9606 GN=KRT10 PE=1 SV=6" 4.14 3069.1 - 212991 - - - 0.9625 - 2.924 0.578 - 585.3 1 1 0 0.0017 15 0 0 0 5.49E+06 0.00E+00 - - - 5.9475 1 221125_WJC_METTL3_EV_vs_WT_F05.18109.18109.3 3.62E-09 15/64 K.TQLIAHDK[136.11]EVYDIAFSR[166.11].A "sp|P61962|DCAF7_HUMAN,tr|A0A087WWI6|A0A087WWI6_HUMAN" 2 2023.0494 1.57 69196 18109 3 2023.053811 675.3571 DDB1- and CUL4-associated factor 7 OS=Homo sapiens OX=9606 GN=DCAF7 PE=1 SV=1 5.35 3069.5 - 818386 - - - 2.1996 - 3.254 0.661 - 304.1 1 2 1 0.0044 17 0 0 0 3.27E+07 2.08E+07 - - - 8.889 1 221125_WJC_METTL3_EV_vs_WT_F05.18110.18110.3 2.98E-08 15/76 K.YQGDGIVEDEEETMENNEEK.K "sp|Q9NYF8|BCLF1_HUMAN,tr|H0YF63|H0YF63_HUMAN,tr|E9PK91|E9PK91_HUMAN,tr|H0YF14|H0YF14_HUMAN" 4 2356.9489 3.38 69197 18110 3 2356.953956 786.6569 Bcl-2-associated transcription factor 1 OS=Homo sapiens OX=9606 GN=BCLAF1 PE=1 SV=2 3.62 3069.6 - 591378 - - - 2.1473 - 3.097 0.628 - 287.6 1 2 0 0.0051 20 0 0 0 5.60E+06 1.66E+06 - - - 8.2826 1 221125_WJC_METTL3_EV_vs_WT_F05.18111.18111.2 4.30E-13 14/28 R.EADSSSDYVNMDFTK[136.11].R "sp|O14654|IRS4_HUMAN,tr|A0A804CF45|A0A804CF45_HUMAN" 2 1715.7076 1.08 69198 18111 2 1715.709144 858.8611 Insulin receptor substrate 4 OS=Homo sapiens OX=9606 GN=IRS4 PE=1 SV=1 3.84 3069.7 - 1.98E+06 - - - 0.9023 - 2.952 0.78 - 754.1 1 2 0 0.0015 15 0 0 0 2.64E+07 2.45E+07 - - - 7.4629 0.9996 221125_WJC_METTL3_EV_vs_WT_F05.18114.18114.3 0.00059 Oct-56 R.EVVNK[136.11]DVLDVYIEHR[166.11].L sp|P33993|MCM7_HUMAN 1 1844.9751 0.7 69201 18114 3 1844.977764 615.999 DNA replication licensing factor MCM7 OS=Homo sapiens OX=9606 GN=MCM7 PE=1 SV=4 4.75 3070 - 482312 - - - 1.426 - 2.322 0.441 - 142.4 1 2 1 0.0026 15 0 0 0 7.39E+06 1.06E+07 - - - 5.6542 0.9998 221125_WJC_METTL3_EV_vs_WT_F05.18118.18118.3 1.74E-07 17/56 R.EVVNKDVLDVYIEHR.L sp|P33993|MCM7_HUMAN 1 1826.9527 0.66 69205 18118 3 1826.957628 609.9915 DNA replication licensing factor MCM7 OS=Homo sapiens OX=9606 GN=MCM7 PE=1 SV=4 4.75 3070.6 - 273519 - - - 2.7176 - 2.977 0.574 - 334.4 1 2 1 0.005 15 0 0 0 6.38E+06 9.61E+06 - - - 7.7848 0.9999 221125_WJC_METTL3_EV_vs_WT_F05.18121.18121.2 1.99E-06 13/30 K.WAVDPQNTAWSNDDSK[136.11].F "sp|Q96BK5|PINX1_HUMAN,tr|E5RGR1|E5RGR1_HUMAN,tr|E5RJG9|E5RJG9_HUMAN,tr|A0A0A6YYK5|A0A0A6YYK5_HUMAN" 4 1840.8108 1.38 69208 18121 2 1840.810019 921.4127 PIN2\TERF1-interacting telomerase inhibitor 1 OS=Homo sapiens OX=9606 GN=PINX1 PE=1 SV=2 3.93 3070.9 - 122074 - - - -0.4004 - 2.117 0.628 - 429.6 1 2 0 -0.0007 16 0 0 0 2.13E+06 1.54E+06 - - - 5.5231 0.9972 221125_WJC_METTL3_EV_vs_WT_F05.18125.18125.4 0.000171 Dec-96 K.TQLIAHDK[136.11]EVYDIAFSR[166.11].A "sp|P61962|DCAF7_HUMAN,tr|A0A087WWI6|A0A087WWI6_HUMAN" 2 2023.0494 1.42 69210 18125 4 2023.053276 506.7696 DDB1- and CUL4-associated factor 7 OS=Homo sapiens OX=9606 GN=DCAF7 PE=1 SV=1 5.35 3071.5 - 1.91E+06 - - - 1.9352 - 2.271 0.331 - 118.1 1 2 1 0.0039 17 0 0 0 3.97E+07 2.80E+07 - - - 2.3907 0.9999 221125_WJC_METTL3_EV_vs_WT_F05.18126.18126.3 6.30E-06 Dec-48 R.ANEK[136.11]EPC[160.03]C[160.03]WWLAK[136.11].V "sp|Q06787|FMR1_HUMAN,tr|R9WNI0|R9WNI0_HUMAN,tr|A8MQB8|A8MQB8_HUMAN,tr|A0A087WXI3|A0A087WXI3_HUMAN,tr|Q8IXW7|Q8IXW7_HUMAN,tr|G3V0J0|G3V0J0_HUMAN" 6 1706.788 0.55 69211 18126 3 1706.789183 569.9366 Synaptic functional regulator FMR1 OS=Homo sapiens OX=9606 GN=FMR1 PE=1 SV=1 6.17 3071.6 - 1.27E+06 - - - 0.7031 - 2.38 0.515 - 196 1 2 1 0.0012 13 0 0 0 6.09E+07 1.10E+08 - - - 6.6324 0.9998 221125_WJC_METTL3_EV_vs_WT_F05.18127.18127.3 5.56E-10 14/52 R.AESLQQEVEALK[136.11]ER[166.11].V "sp|Q14203|DCTN1_HUMAN,tr|A0A804CDA6|A0A804CDA6_HUMAN,tr|E7EX90|E7EX90_HUMAN,tr|A0A7P0Z4C3|A0A7P0Z4C3_HUMAN,tr|Q6AWB1|Q6AWB1_HUMAN" 5 1646.8594 2.05 69212 18127 3 1646.861364 549.9604 Dynactin subunit 1 OS=Homo sapiens OX=9606 GN=DCTN1 PE=1 SV=3 4.49 3071.7 - 1.20E+06 - - - 1.1719 - 3.108 0.413 - 294.3 1 2 1 0.0019 14 0 0 0 1.18E+08 5.74E+07 - - - 6.1576 0.999 221125_WJC_METTL3_EV_vs_WT_F05.18133.18133.3 0.00026 Aug-88 K.VTIPPPSSSVAISNHVTPPPIPK[136.11].S "sp|Q8NC96|NECP1_HUMAN,tr|A0A1W2PR09|A0A1W2PR09_HUMAN,tr|A0A1W2PRM0|A0A1W2PRM0_HUMAN,tr|F5GYH1|F5GYH1_HUMAN,tr|A0A1W2PRL5|A0A1W2PRL5_HUMAN,tr|A0A1W2PNT6|A0A1W2PNT6_HUMAN,tr|F5H2U7|F5H2U7_HUMAN,tr|A0A1W2PRW5|A0A1W2PRW5_HUMAN" 8 2342.3089 0.001 69218 18133 3 2342.317548 781.7769 Adaptin ear-binding coat-associated protein 1 OS=Homo sapiens OX=9606 GN=NECAP1 PE=1 SV=2 8.73 3072.5 - 223515 - - - 3.678 - 1.86 0.431 - 48.1 1 2 0 0.0086 23 0 0 0 0.00E+00 3.42E+06 - - - 4.7987 0.9998 221125_WJC_METTL3_EV_vs_WT_F05.18136.18136.2 6.86E-08 30-Oct K.WAVDPQNTAWSNDDSK.F "sp|Q96BK5|PINX1_HUMAN,tr|E5RGR1|E5RGR1_HUMAN,tr|E5RJG9|E5RJG9_HUMAN,tr|A0A0A6YYK5|A0A0A6YYK5_HUMAN" 4 1832.7966 1.38 69221 18136 2 1832.799058 917.4056 PIN2\TERF1-interacting telomerase inhibitor 1 OS=Homo sapiens OX=9606 GN=PINX1 PE=1 SV=2 3.93 3072.8 - 129412 - - - 1.3651 - 1.911 0.638 - 270.9 1 2 0 0.0025 16 0 0 0 2.13E+06 1.54E+06 - - - 5.3447 1 221125_WJC_METTL3_EV_vs_WT_F05.18138.18138.2 9.43E-15 21/40 R.GQTGGDVNVEMDAAPGVDLSR.L "sp|P08779|K1C16_HUMAN,tr|K7ENW6|K7ENW6_HUMAN" 2 2086.9589 999 69223 18138 2 2086.964297 1044.4867 "Keratin, type I cytoskeletal 16 OS=Homo sapiens OX=9606 GN=KRT16 PE=1 SV=4" 3.84 3073.1 - 91035.8 - - - 2.5635 - 3.745 0.737 - 834.3 1 2 0 0.0053 21 0 0 0 1.43E+08 0.00E+00 - - - 7.7291 0.9991 221125_WJC_METTL3_EV_vs_WT_F05.18142.18142.4 2.84E-05 13/90 K.YFLHDDRDDGVDYWAK.R "sp|Q9NYF8|BCLF1_HUMAN,tr|H0YF14|H0YF14_HUMAN" 2 2013.8857 2.17 69226 18142 4 2013.892378 504.4787 Bcl-2-associated transcription factor 1 OS=Homo sapiens OX=9606 GN=BCLAF1 PE=1 SV=2 4.28 3073.6 - 2.52E+06 - - - 3.313 - 2.5 0.462 - 128.2 1 2 1 0.0067 16 0 0 0 1.15E+09 5.27E+08 - - - 3.5682 0.9979 221125_WJC_METTL3_EV_vs_WT_F05.18144.18144.2 0.0436 16-Aug R.LFEGNALLR.R "sp|P46781|RS9_HUMAN,tr|C9JM19|C9JM19_HUMAN,tr|B5MCT8|B5MCT8_HUMAN" 3 1031.5764 138.43 69227 18144 2 1031.579106 516.7955 40S ribosomal protein S9 OS=Homo sapiens OX=9606 GN=RPS9 PE=1 SV=3 6 3073.8 - 415134 - - - 2.6426 - 1.57 0.339 - 176.6 1 2 0 0.0027 9 0 0 0 4.03E+06 2.91E+04 - - - 2.849 0.9998 221125_WJC_METTL3_EV_vs_WT_F05.18146.18146.3 1.02E-06 Dec-44 K.DIER[166.11]EDIEFIC[160.03]K[136.11].T sp|P50991|TCPD_HUMAN 1 1583.762 0.27 69229 18146 3 1583.76391 528.928 T-complex protein 1 subunit delta OS=Homo sapiens OX=9606 GN=CCT4 PE=1 SV=4 4.18 3074.1 - 307515 - - - 1.1877 - 2.264 0.491 - 196.3 1 2 1 0.0019 12 0 0 0 8.31E+05 3.09E+06 - - - 6.2786 0.8994 221125_WJC_METTL3_EV_vs_WT_F05.18147.18147.3 0.0476 Aug-56 L.TTEIDNNIEQISSYK.S "sp|P13645|K1C10_HUMAN,tr|A0A1B0GVI3|A0A1B0GVI3_HUMAN" 2 1753.837 999 69230 18147 3 1753.837779 585.6196 "Keratin, type I cytoskeletal 10 OS=Homo sapiens OX=9606 GN=KRT10 PE=1 SV=6" 4.14 3074.2 - 264697 - - - 0.4305 - 1.514 0.327 - 60.8 1 1 0 0.0008 15 0 0 0 2.03E+06 0.00E+00 - - - 3.2678 1 221125_WJC_METTL3_EV_vs_WT_F05.18151.18151.3 8.79E-09 14/52 K.EHGGSIVNIIVPTK[136.11].A sp|Q9BY49|PECR_HUMAN 1 1470.8286 1.21 69232 18151 3 1470.832026 491.2835 Peroxisomal trans-2-enoyl-CoA reductase OS=Homo sapiens OX=9606 GN=PECR PE=1 SV=2 6.85 3074.7 - 616056 - - - 2.3443 - 2.746 0.591 - 283.1 1 2 0 0.0034 14 0 0 0 3.14E+07 2.59E+07 - - - 7.8126 1 221125_WJC_METTL3_EV_vs_WT_F05.18154.18154.3 0.000825 13/52 K.NLQAHYEDFLQDSR.D "sp|Q9UPN3|MACF1_HUMAN,tr|H3BQK9|H3BQK9_HUMAN,tr|A0A7P0MQR8|A0A7P0MQR8_HUMAN,tr|E9PNZ4|E9PNZ4_HUMAN,tr|H0Y390|H0Y390_HUMAN,tr|E9PLY5|E9PLY5_HUMAN,tr|H3BPE1|H3BPE1_HUMAN,tr|A0A669KBB0|A0A669KBB0_HUMAN,tr|A0A590UJG2|A0A590UJG2_HUMAN,tr|A0A5F9ZGX0|A0A5F9ZGX0_HUMAN" 10 1734.7962 1.77 69235 18154 3 1734.796966 579.2727 "Microtubule-actin cross-linking factor 1, isoforms 1\2\3\5 OS=Homo sapiens OX=9606 GN=MACF1 PE=1 SV=4" 4.54 3075.1 - 254203 - - - 0.4635 - 2.155 0.498 - 230.9 1 2 0 0.0008 14 0 0 0 2.91E+06 1.64E+06 - - - 6.1324 0.9998 221125_WJC_METTL3_EV_vs_WT_F05.18158.18158.2 0.000102 26-Aug K.GPVEGYEENEEFLR.T sp|Q9UI30|TR112_HUMAN 1 1666.7475 1.28 69239 18158 2 1666.750118 834.381 Multifunctional methyltransferase subunit TRM112-like protein OS=Homo sapiens OX=9606 GN=TRMT112 PE=1 SV=1 3.98 3075.7 - 85588.4 - - - 1.5821 - 1.927 0.591 - 186.1 1 2 0 0.0026 14 0 0 0 8.31E+05 6.50E+05 - - - 5.0514 0.9988 221125_WJC_METTL3_EV_vs_WT_F05.18162.18162.4 0.00248 16/84 R.EVVNKDVLDVYIEHR.L sp|P33993|MCM7_HUMAN 1 1826.9527 0.66 69241 18162 4 1826.957242 457.7454 DNA replication licensing factor MCM7 OS=Homo sapiens OX=9606 GN=MCM7 PE=1 SV=4 4.75 3076.2 - 562345 - - - 2.5064 - 2.976 0.389 - 224.5 1 2 1 0.0046 15 0 0 0 7.30E+06 1.10E+07 - - - 3.0008 1 221125_WJC_METTL3_EV_vs_WT_F05.18163.18163.3 1.97E-07 13/52 K.EHGGSIVNIIVPTK.A sp|Q9BY49|PECR_HUMAN 1 1462.8144 1.16 69242 18163 3 1462.816512 488.6121 Peroxisomal trans-2-enoyl-CoA reductase OS=Homo sapiens OX=9606 GN=PECR PE=1 SV=2 6.85 3076.3 - 853540 - - - 1.4588 - 2.624 0.555 - 224.7 1 2 0 0.0021 14 0 0 0 3.22E+07 2.77E+07 - - - 7.2908 1 221125_WJC_METTL3_EV_vs_WT_F05.18166.18166.3 1.41E-11 17/72 R.NLESHLMSPAEIPGQPVPK.N "sp|Q9NRA8|4ET_HUMAN,tr|B0QYZ7|B0QYZ7_HUMAN" 2 2043.0459 1.22 69245 18166 3 2043.051425 682.0226 Eukaryotic translation initiation factor 4E transporter OS=Homo sapiens OX=9606 GN=EIF4ENIF1 PE=1 SV=2 5.4 3076.7 - 379273 - - - 2.6989 - 2.997 0.618 - 269.6 1 2 0 0.0055 19 0 0 0 1.35E+07 1.10E+07 - - - 8.1252 0.9999 221125_WJC_METTL3_EV_vs_WT_F05.18167.18167.3 2.91E-05 Nov-72 K.IFQNAPTDPTQDFSTQVAK[136.11].L sp|P45974|UBP5_HUMAN 1 2115.0364 2.12 69246 18167 3 2115.039612 706.0194 Ubiquitin carboxyl-terminal hydrolase 5 OS=Homo sapiens OX=9606 GN=USP5 PE=1 SV=2 4.21 3076.8 - 330947 - - - 1.5191 - 2.223 0.449 - 124.9 1 2 0 0.0032 19 0 0 0 7.49E+06 3.52E+06 - - - 5.5077 0.8896 221125_WJC_METTL3_EV_vs_WT_F05.18169.18169.3 0.345 Jul-44 R.DLQANVEHLVQK[136.11].M "sp|P08237|PFKAM_HUMAN,tr|A0A2R8Y891|A0A2R8Y891_HUMAN" 2 1400.7503 0.94 69248 18169 3 1400.751353 467.9241 "ATP-dependent 6-phosphofructokinase, muscle type OS=Homo sapiens OX=9606 GN=PFKM PE=1 SV=2" 5.32 3077.1 - 225257 - - - 0.7318 - 1.265 0.127 - 39.2 3 2 0 0.001 12 0 0 0 2.21E+06 2.35E+06 - - - 0.3864 0.998 221125_WJC_METTL3_EV_vs_WT_F05.18174.18174.2 7.62E-06 26-Sep R.AESLQQEVEALK[136.11]ER[166.11].V "sp|Q14203|DCTN1_HUMAN,tr|A0A804CDA6|A0A804CDA6_HUMAN,tr|E7EX90|E7EX90_HUMAN,tr|A0A7P0Z4C3|A0A7P0Z4C3_HUMAN,tr|Q6AWB1|Q6AWB1_HUMAN" 5 1646.8594 6.14 69253 18174 2 1646.860933 824.437 Dynactin subunit 1 OS=Homo sapiens OX=9606 GN=DCTN1 PE=1 SV=3 4.49 3077.8 - 60697.9 - - - 0.9102 - 2.125 0.501 - 301.7 1 2 1 0.0015 14 0 0 0 4.81E+06 7.83E+05 - - - 4.6325 1 221125_WJC_METTL3_EV_vs_WT_F05.18181.18181.3 4.65E-11 22/68 R.HDIAFVEFENDGQAGAAR.D sp|P08579|RU2B_HUMAN 1 1945.8919 1.4 69258 18181 3 1945.896462 649.6379 U2 small nuclear ribonucleoprotein B'' OS=Homo sapiens OX=9606 GN=SNRPB2 PE=1 SV=1 4.31 3078.5 - 730812 - - - 2.3681 - 3.989 0.692 - 873.1 1 2 0 0.0046 18 0 0 0 1.62E+07 1.16E+07 - - - 9.699 0.9997 221125_WJC_METTL3_EV_vs_WT_F05.18188.18188.2 1.74E-05 Jul-36 K.IFQNAPTDPTQDFSTQVAK.L sp|P45974|UBP5_HUMAN 1 2107.0222 2 69265 18188 2 2107.02037 1054.5184 Ubiquitin carboxyl-terminal hydrolase 5 OS=Homo sapiens OX=9606 GN=USP5 PE=1 SV=2 4.21 3079.4 - 156045 - - - -0.868 - 1.621 0.504 - 65.6 1 2 0 -0.0018 19 0 0 0 1.23E+06 6.12E+05 - - - 3.9506 0.9813 221125_WJC_METTL3_EV_vs_WT_F05.18190.18190.2 2.22E-05 Sep-34 R.VALVNDSLSDVTSTTSSR[166.11].V "sp|Q7Z2W4|ZCCHV_HUMAN,tr|A0A7P0T8C6|A0A7P0T8C6_HUMAN" 2 1860.9304 0.08 69267 18190 2 1861.935428 931.4725 Zinc finger CCCH-type antiviral protein 1 OS=Homo sapiens OX=9606 GN=ZC3HAV1 PE=1 SV=3 4.21 3079.7 - 105236 - - - 540.0562 - 2.224 0.359 - 165.4 1 2 0 1.005 18 0 0 0 2.39E+06 2.82E+07 - - - 3.3421 0.9929 221125_WJC_METTL3_EV_vs_WT_F05.18193.18193.3 0.0248 Nov-64 K.EISELNETFLSDSEKEK.L "sp|Q8IWJ2|GCC2_HUMAN,tr|B8ZZW2|B8ZZW2_HUMAN" 2 1996.9477 1.91 69269 18193 3 1996.954063 666.6565 GRIP and coiled-coil domain-containing protein 2 OS=Homo sapiens OX=9606 GN=GCC2 PE=1 SV=4 4.14 3080 - 327769 - - - 3.1879 - 1.959 0.346 - 109.1 1 2 1 0.0064 17 0 0 0 1.20E+07 6.29E+06 - - - 4.0946 0.9999 221125_WJC_METTL3_EV_vs_WT_F05.18194.18194.4 1.68E-07 20/108 R.LLEAQIATGGIIDPVHSHR.V "sp|P58107|EPIPL_HUMAN,sp|Q15149|PLEC_HUMAN,tr|A0A075B730|A0A075B730_HUMAN,tr|H0YDN1|H0YDN1_HUMAN" 4 2026.096 1.38 69270 18194 4 2026.102663 507.5313 Epiplakin OS=Homo sapiens OX=9606 GN=EPPK1 PE=1 SV=3 5.99 3080.1 - 1.32E+06 - - - 3.3019 - 3.603 0.576 - 328.9 1 2 0 0.0067 19 0 0 0 1.09E+07 7.88E+06 - - - 4.6712 0.9988 221125_WJC_METTL3_EV_vs_WT_F05.18196.18196.4 0.00476 13/120 K.IVASSHDHGYTTLATSVTLLK.A "tr|A0A2R8YEE8|A0A2R8YEE8_HUMAN,tr|A0A0U1RQQ2|A0A0U1RQQ2_HUMAN,tr|B5MCL5|B5MCL5_HUMAN,tr|G5E975|G5E975_HUMAN" 4 2213.1692 0.88 69272 18196 4 2213.174666 554.2996 SWI\SNF-related matrix-associated actin-dependent regulator of chromatin subfamily B member 1 (Fragment) OS=Homo sapiens OX=9606 GN=SMARCB1 PE=1 SV=1 6.92 3080.4 - 480729 - - - 2.4707 - 2.36 0.323 - 97.7 1 2 0 0.0055 21 0 0 0 2.46E+06 2.81E+06 - - - 2.3198 0.9923 221125_WJC_METTL3_EV_vs_WT_F05.18201.18201.4 0.0182 Sep-90 R.DYQGPLKEHEVTIFVR.R "sp|P53396|ACLY_HUMAN,tr|K7EIE7|K7EIE7_HUMAN" 2 1929.9949 0.67 69277 18201 4 1929.999009 483.506 ATP-citrate synthase OS=Homo sapiens OX=9606 GN=ACLY PE=1 SV=3 5.45 3081 - 292360 - - - 2.1487 - 1.902 0.293 - 52.8 1 2 1 0.0041 16 0 0 0 4.34E+06 6.44E+06 - - - 2.0016 1 221125_WJC_METTL3_EV_vs_WT_F05.18202.18202.4 1.37E-06 15/90 K.VLHGEQYLELYK[136.11]PLPR[166.11].A "sp|P51659|DHB4_HUMAN,tr|A0A2R8Y7L2|A0A2R8Y7L2_HUMAN,tr|A0A2R8YD50|A0A2R8YD50_HUMAN,tr|A0A804HIR1|A0A804HIR1_HUMAN,tr|E7ET17|E7ET17_HUMAN,tr|E7ER27|E7ER27_HUMAN,tr|E7EPL9|E7EPL9_HUMAN,tr|A0A804HKU2|A0A804HKU2_HUMAN,tr|A0A804HK65|A0A804HK65_HUMAN" 9 1972.0901 0.36 69278 18202 4 1972.092593 494.0298 Peroxisomal multifunctional enzyme type 2 OS=Homo sapiens OX=9606 GN=HSD17B4 PE=1 SV=3 6.73 3081.1 - 265363 - - - 1.2626 - 2.891 0.533 - 174.4 1 2 0 0.0025 16 0 0 0 9.45E+05 2.66E+06 - - - 4.2385 0.8598 221125_WJC_METTL3_EV_vs_WT_F05.18204.18204.3 0.0179 Oct-44 R.HVNIDHLHVGWY.Q "sp|O15372|EIF3H_HUMAN,tr|B3KS98|B3KS98_HUMAN,tr|A0A087WZK9|A0A087WZK9_HUMAN,tr|E5RFH0|E5RFH0_HUMAN,tr|E5RGU4|E5RGU4_HUMAN,tr|E5RJT0|E5RJT0_HUMAN" 6 1488.7262 - 69280 18204 3 1488.731616 497.2494 Eukaryotic translation initiation factor 3 subunit H OS=Homo sapiens OX=9606 GN=EIF3H PE=1 SV=1 6.25 3081.4 - 180627 - - - 3.6165 - 2.125 0.334 - 104.6 1 1 0 0.0054 12 0 0 0 - - - - - 4.3516 0.9998 221125_WJC_METTL3_EV_vs_WT_F05.18205.18205.3 0.00174 Aug-44 K.EIGNIISDAMKK.V "sp|P10809|CH60_HUMAN,tr|A0A7I2V599|A0A7I2V599_HUMAN,tr|E7EXB4|E7EXB4_HUMAN,tr|A0A7I2YQ71|A0A7I2YQ71_HUMAN,tr|E7ESH4|E7ESH4_HUMAN,tr|A0A7I2V5M1|A0A7I2V5M1_HUMAN,tr|A0A7I2V5K3|A0A7I2V5K3_HUMAN,tr|A0A7I2V369|A0A7I2V369_HUMAN" 8 1317.6962 1.31 69281 18205 3 1317.69688 440.2394 "60 kDa heat shock protein, mitochondrial OS=Homo sapiens OX=9606 GN=HSPD1 PE=1 SV=2" 6.17 3081.5 - 174733 - - - 0.488 - 1.627 0.418 - 85.7 1 2 0 0.0006 12 0 0 0 2.92E+06 2.23E+06 - - - 4.5493 0.9173 221125_WJC_METTL3_EV_vs_WT_F05.18206.18206.2 0.0225 30-Jul K.QEGQVGHYELVMPQAN.- sp|O15226|NKRF_HUMAN 1 1798.8308 - 69282 18206 2 1798.843046 900.4227 NF-kappa-B-repressing factor OS=Homo sapiens OX=9606 GN=NKRF PE=1 SV=2 4.51 3081.6 - 149559 - - - 6.7894 - 1.431 0.29 - 87.4 1 2 0 0.0122 16 0 0 0 - - - - - 2.0602 1 221125_WJC_METTL3_EV_vs_WT_F05.18208.18208.3 6.39E-09 17/68 R.HDIAFVEFENDGQAGAAR[166.11].D sp|P08579|RU2B_HUMAN 1 1955.9001 1.47 69283 18208 3 1955.901739 652.974 U2 small nuclear ribonucleoprotein B'' OS=Homo sapiens OX=9606 GN=SNRPB2 PE=1 SV=1 4.31 3082 - 1.32E+06 - - - 0.8257 - 3.824 0.621 - 411.8 1 2 0 0.0016 18 0 0 0 1.62E+07 1.10E+07 - - - 8.8031 0.9999 221125_WJC_METTL3_EV_vs_WT_F05.18211.18211.3 7.81E-07 14/60 R.ELVFK[136.11]EDGQEYAQVIK[136.11].M "sp|O14602|IF1AY_HUMAN,sp|P47813|IF1AX_HUMAN,tr|A6NJH9|A6NJH9_HUMAN" 3 1910.996 0.71 69285 18211 3 1910.998948 638.006 "Eukaryotic translation initiation factor 1A, Y-chromosomal OS=Homo sapiens OX=9606 GN=EIF1AY PE=1 SV=4" 4.41 3082.3 - 2.02E+06 - - - 1.5196 - 2.922 0.555 - 225.1 1 2 1 0.0029 16 0 0 0 1.09E+07 1.53E+07 - - - 7.4782 0.9998 221125_WJC_METTL3_EV_vs_WT_F05.18212.18212.3 2.00E-06 13/60 R.ELVFKEDGQEYAQVIK.M "sp|O14602|IF1AY_HUMAN,sp|P47813|IF1AX_HUMAN,tr|A6NJH9|A6NJH9_HUMAN" 3 1894.9676 0.66 69286 18212 3 1894.971022 632.6632 "Eukaryotic translation initiation factor 1A, Y-chromosomal OS=Homo sapiens OX=9606 GN=EIF1AY PE=1 SV=4" 4.41 3082.4 - 1.27E+06 - - - 1.7826 - 2.588 0.54 - 170.5 1 2 1 0.0034 16 0 0 0 1.10E+07 1.65E+07 - - - 6.9994 1 221125_WJC_METTL3_EV_vs_WT_F05.18213.18213.3 5.40E-10 18/56 K.HLEINPDHSIIETLR.Q sp|P07900|HS90A_HUMAN 1 1785.9373 0.64 69287 18213 3 1785.939968 596.3197 Heat shock protein HSP 90-alpha OS=Homo sapiens OX=9606 GN=HSP90AA1 PE=1 SV=5 5.27 3082.4 - 1.22E+06 - - - 1.4676 - 3.925 0.612 - 519.4 1 2 0 0.0026 15 0 0 0 6.06E+07 9.43E+07 - - - 8.9304 1 221125_WJC_METTL3_EV_vs_WT_F05.18214.18214.3 2.30E-10 16/96 R.AAAASAAEAGIATTGTEDSDDALLK.M "sp|P55036|PSMD4_HUMAN,sp|A2A3N6|PIPSL_HUMAN,tr|H0Y3Y9|H0Y3Y9_HUMAN" 3 2319.1078 1.12 69288 18214 3 2319.108452 774.0432 26S proteasome non-ATPase regulatory subunit 4 OS=Homo sapiens OX=9606 GN=PSMD4 PE=1 SV=1 3.77 3082.6 - 820321 - - - 0.2902 - 3.881 0.623 - 232.8 1 2 0 0.0007 25 0 0 0 5.28E+06 4.70E+06 - - - 8.6055 0.9681 221125_WJC_METTL3_EV_vs_WT_F05.18215.18215.3 0.000494 Nov-56 K.R[166.11]GLLQDDAHPTLVTY.A "sp|Q86U44|MTA70_HUMAN,tr|F5H6D8|F5H6D8_HUMAN,tr|H0YFV6|H0YFV6_HUMAN,tr|B4DTN4|B4DTN4_HUMAN" 4 1707.882 0.01 69289 18215 3 1707.882629 570.3013 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 5.21 3082.6 - 791397 - - - 0.3952 - 1.914 0.355 - 125.7 1 1 0 0.0007 15 0 0 0 1.28E+05 1.35E+07 - - - 4.1917 0.9565 221125_WJC_METTL3_EV_vs_WT_F05.18220.18220.3 0.15 Jul-60 R.TATFSTDGILTSVNHR[166.11].S sp|Q8WVS4|DC2I1_HUMAN 1 1728.867 0.49 69294 18220 3 1728.873495 577.2963 Cytoplasmic dynein 2 intermediate chain 1 OS=Homo sapiens OX=9606 GN=DYNC2I1 PE=1 SV=3 6.41 3083.3 - 183169 - - - 3.7377 - 1.391 0.238 - 54.3 1 2 0 0.0065 16 0 0 0 1.01E+06 2.06E+06 - - - 2.0385 0.846 221125_WJC_METTL3_EV_vs_WT_F05.18227.18227.4 0.0193 18/108 R.LLEAQIATGGIIDPVHSHR[166.11].V "sp|P58107|EPIPL_HUMAN,sp|Q15149|PLEC_HUMAN,tr|A0A075B730|A0A075B730_HUMAN,tr|H0YDN1|H0YDN1_HUMAN" 4 2036.1042 1.37 69299 18227 4 2037.097234 510.0333 Epiplakin OS=Homo sapiens OX=9606 GN=EPPK1 PE=1 SV=3 5.99 3084.1 - 1.31E+06 - - - 487.6916 - 2.757 0.363 - 225.9 1 2 0 0.993 19 0 0 0 1.09E+07 7.92E+06 - - - 2.4536 1 221125_WJC_METTL3_EV_vs_WT_F05.18228.18228.3 3.43E-11 20/68 R.SELHIENLNMEADPGQYR.C "sp|P35613|BASI_HUMAN,tr|A0A7P0T8A7|A0A7P0T8A7_HUMAN,tr|A0A087WUV8|A0A087WUV8_HUMAN,tr|A0A7P0TA85|A0A7P0TA85_HUMAN,tr|A0A7P0TB04|A0A7P0TB04_HUMAN" 5 2114.9691 1.23 69300 18228 3 2114.967587 705.997 Basigin OS=Homo sapiens OX=9606 GN=BSG PE=1 SV=2 4.4 3084.3 - 802433 - - - -0.7239 - 3.922 0.644 - 270.9 1 2 0 -0.0015 18 0 0 0 1.14E+07 9.25E+06 - - - 9.1225 0.9999 221125_WJC_METTL3_EV_vs_WT_F05.18230.18230.3 0.000554 14/56 R.HSIAQLDPEALGNIK[136.11].K sp|Q53HL2|BOREA_HUMAN 1 1612.8664 1.48 69302 18230 3 1612.870211 538.6294 Borealin OS=Homo sapiens OX=9606 GN=CDCA8 PE=1 SV=2 5.32 3084.5 - 542872 - - - 2.3499 - 2.853 0.397 - 313.1 1 2 0 0.0038 15 0 0 0 6.98E+06 4.72E+06 - - - 5.7007 1 221125_WJC_METTL3_EV_vs_WT_F05.18232.18232.3 0.00196 14/72 K.FVLC[160.03]PEC[160.03]ENPETDLHVNPK.K "sp|P55010|IF5_HUMAN,tr|H0YLZ1|H0YLZ1_HUMAN,tr|H0YN40|H0YN40_HUMAN" 3 2297.0457 0.94 69304 18232 3 2297.050258 766.6892 Eukaryotic translation initiation factor 5 OS=Homo sapiens OX=9606 GN=EIF5 PE=1 SV=2 4.4 3084.7 - 373331 - - - 2.0043 - 3.19 0.614 - 172.6 1 2 0 0.0046 19 0 0 0 8.45E+06 9.00E+06 - - - 8.2342 1 221125_WJC_METTL3_EV_vs_WT_F05.18233.18233.2 6.98E-10 19/34 R.VALVNDSLSDVTSTTSSR.V "sp|Q7Z2W4|ZCCHV_HUMAN,tr|A0A7P0T8C6|A0A7P0T8C6_HUMAN" 2 1850.9222 0.16 69305 18233 2 1850.928309 926.4684 Zinc finger CCCH-type antiviral protein 1 OS=Homo sapiens OX=9606 GN=ZC3HAV1 PE=1 SV=3 4.21 3084.9 - 355051 - - - 3.327 - 3.791 0.702 - 1258.5 1 2 0 0.0062 18 0 0 0 2.39E+06 1.50E+07 - - - 7.5004 0.9993 221125_WJC_METTL3_EV_vs_WT_F05.18235.18235.4 0.00888 8/192 R.SDSPVPTAPTSGGPK[136.11]PSTASAVPELATDPELEK[136.11].K "sp|Q86U44|MTA70_HUMAN,tr|B4E349|B4E349_HUMAN,tr|F5H6D8|F5H6D8_HUMAN,tr|B4DTN4|B4DTN4_HUMAN" 4 3248.6271 0.001 69307 18235 4 3248.624482 813.1641 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 4.18 3085.1 - 205868 - - - -0.8053 - 1.574 0.327 - 7.6 1 2 0 -0.0026 33 0 0 0 0.00E+00 4.77E+06 - - - 2.2076 1 221125_WJC_METTL3_EV_vs_WT_F05.18239.18239.3 4.89E-09 17/80 R.GQTGGDVNVEMDAAPGVDLSR.L "sp|P08779|K1C16_HUMAN,tr|K7ENW6|K7ENW6_HUMAN" 2 2086.9589 999 69310 18239 3 2086.96418 696.6603 "Keratin, type I cytoskeletal 16 OS=Homo sapiens OX=9606 GN=KRT16 PE=1 SV=4" 3.84 3085.7 - 1.12E+07 - - - 2.5075 - 3.459 0.682 - 201.1 1 2 0 0.0052 21 0 0 0 2.46E+08 0.00E+00 - - - 9.1174 0.9996 221125_WJC_METTL3_EV_vs_WT_F05.18241.18241.3 0.000208 Dec-52 K.DK[136.11]LEQAQNELSAWK[136.11].F "sp|Q15007|FL2D_HUMAN,tr|A0A087X1R4|A0A087X1R4_HUMAN" 2 1674.8548 1.04 69312 18241 3 1674.857706 559.2922 Pre-mRNA-splicing regulator WTAP OS=Homo sapiens OX=9606 GN=WTAP PE=1 SV=2 4.68 3085.9 - 762749 - - - 1.7351 - 2.574 0.429 - 224.6 1 2 1 0.0029 14 0 0 0 5.42E+06 5.20E+06 - - - 5.8347 0.9997 221125_WJC_METTL3_EV_vs_WT_F05.18242.18242.2 6.59E-05 28-Nov R.YFQINQDEEEEEDED.- "sp|P35268|RL22_HUMAN,tr|K7ERI7|K7ERI7_HUMAN" 2 1930.7228 - 69313 18242 2 1930.725724 966.3687 60S ribosomal protein L22 OS=Homo sapiens OX=9606 GN=RPL22 PE=1 SV=2 3.35 3086 - 593924 - - - 1.4927 - 1.987 0.511 - 191.8 1 2 0 0.0029 15 0 0 0 - - - - - 4.5024 1 221125_WJC_METTL3_EV_vs_WT_F05.18244.18244.3 2.04E-13 21/76 K.AEAESLYQSKYEELQITAGR.H sp|P04264|K2C1_HUMAN 1 2285.1176 999 69315 18244 3 2285.12486 762.7131 "Keratin, type II cytoskeletal 1 OS=Homo sapiens OX=9606 GN=KRT1 PE=1 SV=6" 4.49 3086.3 - 422648 - - - 3.1963 - 3.819 0.675 - 546.6 1 2 1 0.0073 20 0 0 0 2.90E+06 0.00E+00 - - - 9.3144 0.8449 221125_WJC_METTL3_EV_vs_WT_F05.18248.18248.3 0.0184 Nov-72 R.ENDAVWLATQNHSTLVTER[166.11].S "sp|Q9Y2X7|GIT1_HUMAN,tr|J3QLH1|J3QLH1_HUMAN,tr|A0A0C4DGN6|A0A0C4DGN6_HUMAN,tr|J3QRU8|J3QRU8_HUMAN" 4 2193.069 0.05 69319 18248 3 2193.084216 732.0303 ARF GTPase-activating protein GIT1 OS=Homo sapiens OX=9606 GN=GIT1 PE=1 SV=2 4.65 3086.8 - 169552 - - - 6.9473 - 1.686 0.242 - 74.3 1 2 0 0.0152 19 0 0 0 4.41E+04 8.38E+05 - - - 2.5172 0.9994 221125_WJC_METTL3_EV_vs_WT_F05.18256.18256.3 4.87E-09 16/64 K.SHIAEGPADLEDPFNPK.A sp|Q9NUL7|DDX28_HUMAN 1 1835.869 1.08 69326 18256 3 1835.881685 612.9636 Probable ATP-dependent RNA helicase DDX28 OS=Homo sapiens OX=9606 GN=DDX28 PE=1 SV=2 4.31 3087.6 - 1.00E+06 - - - 6.9133 - 3.196 0.602 - 349.4 1 2 0 0.0127 17 0 0 0 1.89E+07 1.74E+07 - - - 8.1835 0.9994 221125_WJC_METTL3_EV_vs_WT_F05.18257.18257.3 1.10E-07 15/52 K.DKLEQAQNELSAWK.F "sp|Q15007|FL2D_HUMAN,tr|A0A087X1R4|A0A087X1R4_HUMAN" 2 1658.8264 1.06 69327 18257 3 1658.831699 553.9494 Pre-mRNA-splicing regulator WTAP OS=Homo sapiens OX=9606 GN=WTAP PE=1 SV=2 4.68 3087.7 - 989396 - - - 3.1944 - 2.408 0.514 - 434.4 1 2 1 0.0053 14 0 0 0 5.50E+06 5.17E+06 - - - 6.6046 0.9998 221125_WJC_METTL3_EV_vs_WT_F05.18258.18258.3 1.19E-05 Sep-52 K.YQEEFEHFQQELDK[136.11].K sp|P49257|LMAN1_HUMAN 1 1876.8359 1.56 69328 18258 3 1876.842362 626.6192 Protein ERGIC-53 OS=Homo sapiens OX=9606 GN=LMAN1 PE=1 SV=2 4.25 3087.8 - 879986 - - - 3.4388 - 2.232 0.528 - 50 1 2 0 0.0065 14 0 0 0 6.57E+06 4.20E+06 - - - 6.5586 0.9996 221125_WJC_METTL3_EV_vs_WT_F05.18260.18260.4 1.07E-06 18/96 R.LAADDFRTKYETELNLR.M sp|P02533|K1C14_HUMAN 1 2054.0433 105.07 69330 18260 4 2054.049096 514.5181 "Keratin, type I cytoskeletal 14 OS=Homo sapiens OX=9606 GN=KRT14 PE=1 SV=4" 4.78 3088.1 - 614725 - - - 2.8368 - 3.501 0.478 - 361.7 1 2 2 0.0058 17 0 0 0 2.69E+06 2.56E+04 - - - 3.82 0.9995 221125_WJC_METTL3_EV_vs_WT_F05.18262.18262.4 8.07E-06 16/90 R.C[160.03]RIEPHTGLLLLSVQK.R sp|P15924|DESP_HUMAN 1 1863.04 16.26 69332 18262 4 1863.046892 466.7673 Desmoplakin OS=Homo sapiens OX=9606 GN=DSP PE=1 SV=3 8.23 3088.3 - 382395 - - - 3.6789 - 3.277 0.518 - 269.5 1 2 1 0.0069 16 0 0 0 3.63E+06 2.23E+05 - - - 4.1509 1 221125_WJC_METTL3_EV_vs_WT_F05.18263.18263.3 9.62E-14 23/108 Q.SAAAATGSYGAAAAYGAQPSATLAAPYR.T sp|Q96PK6|RBM14_HUMAN 1 2585.251 2.21 69333 18263 3 2585.259646 862.7576 RNA-binding protein 14 OS=Homo sapiens OX=9606 GN=RBM14 PE=1 SV=2 8.22 3088.4 - 371867 - - - 3.3328 - 4.106 0.72 - 285.9 1 1 0 0.0086 28 0 0 0 4.85E+06 2.19E+06 - - - 9.8144 0.9999 221125_WJC_METTL3_EV_vs_WT_F05.18265.18265.3 5.97E-11 16/52 R.RDEPTGEVLSLVGK.L "sp|O75643|U520_HUMAN,tr|A0A494C1A5|A0A494C1A5_HUMAN" 2 1498.7991 1.85 69335 18265 3 1498.805445 500.607 U5 small nuclear ribonucleoprotein 200 kDa helicase OS=Homo sapiens OX=9606 GN=SNRNP200 PE=1 SV=2 4.68 3088.7 - 324427 - - - 4.2187 - 3.008 0.584 - 386.7 1 2 0 0.0063 14 0 0 0 6.58E+06 3.56E+06 - - - 7.9759 1 221125_WJC_METTL3_EV_vs_WT_F05.18266.18266.3 4.02E-07 14/60 K.MLDAEDIVNTARPDEK.A sp|O43707|ACTN4_HUMAN 1 1815.8673 1.31 69336 18266 3 1815.870184 606.2964 Alpha-actinin-4 OS=Homo sapiens OX=9606 GN=ACTN4 PE=1 SV=2 4.1 3088.8 - 303791 - - - 1.6003 - 2.86 0.563 - 167.1 1 2 0 0.0029 16 0 0 0 4.60E+06 3.50E+06 - - - 7.5124 0.9997 221125_WJC_METTL3_EV_vs_WT_F05.18268.18268.3 0.000323 Sep-36 R.KDGAMFFHWR.R "sp|Q9NPF5|DMAP1_HUMAN,tr|Q5TG39|Q5TG39_HUMAN,tr|Q5TG38|Q5TG38_HUMAN,tr|Q5TG40|Q5TG40_HUMAN,tr|Q5TG36|Q5TG36_HUMAN,tr|Q5TG37|Q5TG37_HUMAN" 6 1293.6077 0.87 69338 18268 3 1293.610617 432.2098 DNA methyltransferase 1-associated protein 1 OS=Homo sapiens OX=9606 GN=DMAP1 PE=1 SV=1 8.75 3089.1 - 221817 - - - 2.2573 - 1.799 0.423 - 124.8 1 2 0 0.0029 10 0 0 0 8.49E+05 9.71E+05 - - - 4.9702 0.999 221125_WJC_METTL3_EV_vs_WT_F05.18269.18269.3 1.85E-12 20/108 Q.SAAAATGSYGAAAAYGAQPSATLAAPYR[166.11].T sp|Q96PK6|RBM14_HUMAN 1 2595.2593 2.21 69339 18269 3 2595.260183 866.0937 RNA-binding protein 14 OS=Homo sapiens OX=9606 GN=RBM14 PE=1 SV=2 8.22 3089.2 - 204960 - - - 0.3402 - 3.81 0.612 - 222.3 1 1 0 0.0009 28 0 0 0 4.85E+06 2.19E+06 - - - 8.4404 0.9975 221125_WJC_METTL3_EV_vs_WT_F05.18270.18270.3 0.015 Sep-56 K.SGILEAAGFPDPGKK.A "sp|P10070|GLI2_HUMAN,tr|F2Z2B4|F2Z2B4_HUMAN,tr|A0A7I2PJA1|A0A7I2PJA1_HUMAN,tr|H7C1U2|H7C1U2_HUMAN,tr|A0A6Q8PH00|A0A6Q8PH00_HUMAN,tr|Q1PSW9|Q1PSW9_HUMAN" 6 1485.7827 0.45 69340 18270 3 1485.788301 496.2682 Zinc finger protein GLI2 OS=Homo sapiens OX=9606 GN=GLI2 PE=1 SV=4 5.79 3089.4 - 173784 - - - 3.7401 - 1.83 0.351 - 51 1 2 0 0.0056 15 0 0 0 1.91E+06 4.28E+06 - - - 4.0286 0.9962 221125_WJC_METTL3_EV_vs_WT_F05.18274.18274.3 7.73E-06 17/68 K.PSTASAVPELATDPELEK[136.11].K "sp|Q86U44|MTA70_HUMAN,tr|B4E349|B4E349_HUMAN,tr|F5H6D8|F5H6D8_HUMAN,tr|H0YFV6|H0YFV6_HUMAN,tr|B4DTN4|B4DTN4_HUMAN" 5 1861.94 0.03 69343 18274 3 1861.943928 621.654 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 4 3089.8 - 1.87E+06 - - - 2.0887 - 3.342 0.511 - 321.1 1 1 0 0.0039 18 0 0 0 9.27E+05 2.73E+07 - - - 7.2405 0.9997 221125_WJC_METTL3_EV_vs_WT_F05.18277.18277.3 2.22E-05 Dec-44 R.GREFSFEAWNAK.L "sp|P78347|GTF2I_HUMAN,tr|A0A494C1K3|A0A494C1K3_HUMAN" 2 1440.6786 1.45 69346 18277 3 1440.681469 481.2335 General transcription factor II-I OS=Homo sapiens OX=9606 GN=GTF2I PE=1 SV=2 6.14 3090 - 767626 - - - 1.9824 - 2.418 0.484 - 144.6 1 2 1 0.0029 12 0 0 0 9.80E+06 6.76E+06 - - - 6.3827 1 221125_WJC_METTL3_EV_vs_WT_F05.18282.18282.3 1.79E-08 16/72 K.SMIMFGSQENK[136.11]DPLSASSR[166.11].L "sp|O95071|UBR5_HUMAN,tr|E7EMW7|E7EMW7_HUMAN" 2 2101.9891 50.08 69351 18282 3 2101.988912 701.6703 E3 ubiquitin-protein ligase UBR5 OS=Homo sapiens OX=9606 GN=UBR5 PE=1 SV=2 5.79 3090.7 - 264457 - - - -0.1108 - 3.071 0.643 - 298.4 1 2 1 -0.0002 19 0 0 0 1.88E+08 3.76E+06 - - - 8.4653 0.9918 221125_WJC_METTL3_EV_vs_WT_F05.18283.18283.3 0.0125 Sep-60 K.YFLHDDRDDGVDYWAK.R "sp|Q9NYF8|BCLF1_HUMAN,tr|H0YF14|H0YF14_HUMAN" 2 2013.8857 2.41 69352 18283 3 2013.89042 672.3025 Bcl-2-associated transcription factor 1 OS=Homo sapiens OX=9606 GN=BCLAF1 PE=1 SV=2 4.28 3090.8 - 224368 - - - 2.3407 - 1.59 0.341 - 89 1 2 1 0.0047 16 0 0 0 7.65E+06 3.18E+06 - - - 3.5304 0.9763 221125_WJC_METTL3_EV_vs_WT_F05.18285.18285.3 0.00285 Oct-76 K.AGVPLPPNLKPAPPPTIEEK.V "sp|P18583|SON_HUMAN,tr|H7C1M2|H7C1M2_HUMAN,tr|H7C2G8|H7C2G8_HUMAN,tr|J3QSZ5|J3QSZ5_HUMAN" 4 2064.1619 3.91 69354 18285 3 2064.174359 689.0613 Protein SON OS=Homo sapiens OX=9606 GN=SON PE=1 SV=4 6.19 3091.1 - 143450 - - - 6.0223 - 1.732 0.329 - 86.8 1 2 0 0.0124 20 0 0 0 4.57E+05 1.17E+05 - - - 3.5371 0.9807 221125_WJC_METTL3_EV_vs_WT_F05.18287.18287.3 0.000555 Sep-44 D.GIHLLDPDVVAR[166.11].F sp|Q86U44|MTA70_HUMAN 1 1313.7331 0.1 69356 18287 3 1313.734382 438.9183 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 5.21 3091.4 - 125357 - - - 0.972 - 1.901 0.393 - 106.9 1 1 0 0.0013 12 0 0 0 6.34E+04 6.49E+05 - - - 4.7018 0.9959 221125_WJC_METTL3_EV_vs_WT_F05.18288.18288.2 5.14E-05 Jun-40 K.DSDFSLPPGSASGPTGSPVVK.L "sp|Q5JSZ5|PRC2B_HUMAN,tr|A0A804HKC3|A0A804HKC3_HUMAN,tr|A0A804HJR4|A0A804HJR4_HUMAN" 3 2000.9691 5.07 69357 18288 2 2000.978741 1001.4918 Protein PRRC2B OS=Homo sapiens OX=9606 GN=PRRC2B PE=1 SV=2 4.21 3091.5 - 122911 - - - 4.8177 - 1.424 0.536 - 38.9 1 2 0 0.0096 21 0 0 0 1.64E+06 3.24E+05 - - - 3.8659 0.9996 221125_WJC_METTL3_EV_vs_WT_F05.18293.18293.3 0.000531 Dec-44 R.GR[166.11]EFSFEAWNAK[136.11].L "sp|P78347|GTF2I_HUMAN,tr|A0A494C1K3|A0A494C1K3_HUMAN" 2 1458.7011 1.48 69360 18293 3 1458.703896 487.241 General transcription factor II-I OS=Homo sapiens OX=9606 GN=GTF2I PE=1 SV=2 6.14 3092.2 - 1.17E+06 - - - 1.9284 - 2.384 0.46 - 159.5 1 2 1 0.0028 12 0 0 0 9.80E+06 6.62E+06 - - - 6.0759 1 221125_WJC_METTL3_EV_vs_WT_F05.18294.18294.3 3.73E-12 17/64 K.SHIAEGPADLEDPFNPK[136.11].A sp|Q9NUL7|DDX28_HUMAN 1 1843.8832 1.06 69361 18294 3 1843.886613 615.635 Probable ATP-dependent RNA helicase DDX28 OS=Homo sapiens OX=9606 GN=DDX28 PE=1 SV=2 4.31 3092.2 - 1.78E+06 - - - 1.8548 - 3.439 0.695 - 377.8 1 2 0 0.0034 17 0 0 0 1.89E+07 1.79E+07 - - - 9.4081 1 221125_WJC_METTL3_EV_vs_WT_F05.18297.18297.3 1.49E-10 16/52 R.R[166.11]DEPTGEVLSLVGK[136.11].L "sp|O75643|U520_HUMAN,tr|A0A494C1A5|A0A494C1A5_HUMAN" 2 1516.8216 2.17 69364 18297 3 1516.824596 506.6145 U5 small nuclear ribonucleoprotein 200 kDa helicase OS=Homo sapiens OX=9606 GN=SNRNP200 PE=1 SV=2 4.68 3092.6 - 416568 - - - 1.9805 - 2.993 0.654 - 585.3 1 2 0 0.003 14 0 0 0 2.26E+07 1.04E+07 - - - 8.744 0.9973 221125_WJC_METTL3_EV_vs_WT_F05.18299.18299.3 0.0393 Aug-44 K.SPYQEFTDHLVK[136.11].T "sp|P15880|RS2_HUMAN,tr|E9PQD7|E9PQD7_HUMAN,tr|H0YEN5|H0YEN5_HUMAN" 3 1470.7234 1.01 69366 18299 3 1470.727107 491.2484 40S ribosomal protein S2 OS=Homo sapiens OX=9606 GN=RPS2 PE=1 SV=2 5.3 3092.8 - 365090 - - - 2.4899 - 1.347 0.354 - 71.6 1 2 0 0.0037 12 0 0 0 7.94E+06 7.88E+06 - - - 3.3114 0.9967 221125_WJC_METTL3_EV_vs_WT_F05.18300.18300.3 0.000308 14/52 K.LREIFGLYGQTTGK.G "sp|Q9NR31|SAR1A_HUMAN,tr|H0Y5E8|H0Y5E8_HUMAN" 2 1581.8515 0.82 69367 18300 3 1581.85628 528.2911 GTP-binding protein SAR1a OS=Homo sapiens OX=9606 GN=SAR1A PE=1 SV=1 8.59 3093 - 318278 - - - 3.0268 - 1.875 0.396 - 232.8 1 2 1 0.0048 14 0 0 0 2.32E+06 2.81E+06 - - - 4.6242 1 221125_WJC_METTL3_EV_vs_WT_F05.18311.18311.3 1.38E-06 17/56 K.TQAIVC[160.03]QQLDLTHLK[136.11].E "sp|P61221|ABCE1_HUMAN,tr|D6RGF4|D6RGF4_HUMAN,tr|D6R9I9|D6R9I9_HUMAN" 3 1774.9491 0.5 69376 18311 3 1774.951087 592.657 ATP-binding cassette sub-family E member 1 OS=Homo sapiens OX=9606 GN=ABCE1 PE=1 SV=1 6.4 3094.3 - 811391 - - - 1.1167 - 3.256 0.545 - 495.7 1 2 0 0.002 15 0 0 0 2.64E+06 5.28E+06 - - - 7.696 0.9773 221125_WJC_METTL3_EV_vs_WT_F05.18312.18312.4 1.97E-07 19/96 L.SWLDANTLAEK[136.11]DEFEHK[136.11].R "sp|P0DMV8|HS71A_HUMAN,sp|P0DMV9|HS71B_HUMAN,tr|V9GZ37|V9GZ37_HUMAN,tr|A0A0G2JIW1|A0A0G2JIW1_HUMAN" 4 2047.9822 0.07 69377 18312 4 2047.984652 513.0028 Heat shock 70 kDa protein 1A OS=Homo sapiens OX=9606 GN=HSPA1A PE=1 SV=1 4.5 3094.4 - 627893 - - - 1.2046 - 3.582 0.459 - 270.5 1 1 1 0.0025 17 0 0 0 3.01E+05 4.02E+06 - - - 3.6634 0.7855 221125_WJC_METTL3_EV_vs_WT_F05.18313.18313.3 2.32 Jul-64 R.C[160.03]PVKTC[160.03]AGQQDNGIR[166.11]C[160.03]R[166.11].D sp|O75339|CILP1_HUMAN 1 2038.9362 - 69378 18313 3 2038.935971 680.6527 Cartilage intermediate layer protein 1 OS=Homo sapiens OX=9606 GN=CILP PE=1 SV=4 8.71 3094.5 - 1.68E+06 - - - -0.1236 - 1.279 0.146 - 35.9 1 2 2 -0.0003 17 0 0 0 - - - - - 0.7894 0.9999 221125_WJC_METTL3_EV_vs_WT_F05.18315.18315.4 6.29E-06 26/108 K.LAAAILGGVDQIHIK[136.11]PGAK[136.11].V "sp|P22087|FBRL_HUMAN,tr|M0R299|M0R299_HUMAN,tr|M0R0P1|M0R0P1_HUMAN,tr|M0R1H0|M0R1H0_HUMAN,tr|M0QXL5|M0QXL5_HUMAN,tr|M0R2Q4|M0R2Q4_HUMAN,tr|M0R2B0|M0R2B0_HUMAN,tr|M0R2U2|M0R2U2_HUMAN" 8 1887.1277 -1 69380 18315 4 1887.129276 472.7892 rRNA 2'-O-methyltransferase fibrillarin OS=Homo sapiens OX=9606 GN=FBL PE=1 SV=2 8.6 3094.8 - 576123 - - - 0.8521 - 3.51 0.437 - 743.2 1 2 0 0.0016 19 0 0 0 0.00E+00 0.00E+00 - - - 3.454 0.9898 221125_WJC_METTL3_EV_vs_WT_F05.18317.18317.3 0.000549 13/64 R.HVDAHATLNDGVVVQVM.G "sp|Q13283|G3BP1_HUMAN,tr|A0A7I2YQB1|A0A7I2YQB1_HUMAN,tr|A0A7I2V5M7|A0A7I2V5M7_HUMAN,tr|E5RH42|E5RH42_HUMAN,tr|A0A7P0P2U7|A0A7P0P2U7_HUMAN,tr|A0A7I2YQU8|A0A7I2YQU8_HUMAN,tr|E5RJU8|E5RJU8_HUMAN,tr|A0A7I2YQQ8|A0A7I2YQQ8_HUMAN,tr|A0A7I2V651|A0A7I2V651_HUMAN,tr|E5RIF8|E5RIF8_HUMAN,tr|A0A7I2YQN9|A0A7I2YQN9_HUMAN" 11 1803.8938 - 69382 18317 3 1803.895566 602.3052 Ras GTPase-activating protein-binding protein 1 OS=Homo sapiens OX=9606 GN=G3BP1 PE=1 SV=1 5.05 3095 - 370804 - - - 0.9967 - 2.195 0.429 - 151.8 1 1 0 0.0018 17 0 0 0 - - - - - 5.3086 1 221125_WJC_METTL3_EV_vs_WT_F05.18320.18320.4 0.000454 Dec-84 K.FDLHSSSHIDTLLER[166.11].E "sp|Q5H9R7|PP6R3_HUMAN,tr|H7BXH2|H7BXH2_HUMAN,tr|E9PJD8|E9PJD8_HUMAN,tr|E9PNN8|E9PNN8_HUMAN,tr|E9PKF6|E9PKF6_HUMAN,tr|E9PKG4|E9PKG4_HUMAN" 6 1778.8827 0.92 69385 18320 4 1778.883624 445.7279 Serine\threonine-protein phosphatase 6 regulatory subunit 3 OS=Homo sapiens OX=9606 GN=PPP6R3 PE=1 SV=2 5.21 3095.4 - 349978 - - - 0.529 - 2.336 0.49 - 49.7 1 2 0 0.0009 15 0 0 0 1.50E+06 1.64E+06 - - - 3.7943 1 221125_WJC_METTL3_EV_vs_WT_F05.18321.18321.4 9.96E-08 23/108 K.LAAAILGGVDQIHIKPGAK.V "sp|P22087|FBRL_HUMAN,tr|M0R299|M0R299_HUMAN,tr|M0R0P1|M0R0P1_HUMAN,tr|M0R1H0|M0R1H0_HUMAN,tr|M0QXL5|M0QXL5_HUMAN,tr|M0R2Q4|M0R2Q4_HUMAN,tr|M0R2B0|M0R2B0_HUMAN,tr|M0R2U2|M0R2U2_HUMAN" 8 1871.0993 -1 69386 18321 4 1871.102465 468.7821 rRNA 2'-O-methyltransferase fibrillarin OS=Homo sapiens OX=9606 GN=FBL PE=1 SV=2 8.6 3095.5 - 338040 - - - 1.7086 - 3.469 0.554 - 561.7 1 2 0 0.0032 19 0 0 0 0.00E+00 0.00E+00 - - - 4.4679 1 221125_WJC_METTL3_EV_vs_WT_F05.18323.18323.3 7.67E-09 14/52 R.AHQVVEDGYEFFAK.R "sp|P62136|PP1A_HUMAN,sp|P62140|PP1B_HUMAN,sp|P36873|PP1G_HUMAN,tr|A0A7I2V4F7|A0A7I2V4F7_HUMAN,tr|F8W0W8|F8W0W8_HUMAN,tr|F8VYE8|F8VYE8_HUMAN,tr|E9PMD7|E9PMD7_HUMAN" 7 1638.7678 1.44 69388 18323 3 1638.768692 547.2632 Serine\threonine-protein phosphatase PP1-alpha catalytic subunit OS=Homo sapiens OX=9606 GN=PPP1CA PE=1 SV=1 4.65 3095.8 - 270007 - - - 0.5309 - 2.776 0.668 - 286.8 1 2 0 0.0009 14 0 0 0 5.09E+06 3.53E+06 - - - 8.7007 0.9976 221125_WJC_METTL3_EV_vs_WT_F05.18333.18333.3 0.00862 Oct-44 R.YLYTLVITDKEK.A "sp|P63173|RL38_HUMAN,tr|J3KT73|J3KT73_HUMAN,tr|J3QL01|J3QL01_HUMAN" 3 1484.8126 1.5 69396 18333 3 1484.814105 495.9448 60S ribosomal protein L38 OS=Homo sapiens OX=9606 GN=RPL38 PE=1 SV=2 6.07 3097.1 - 1.16E+06 - - - 0.9819 - 1.749 0.337 - 85 1 2 1 0.0015 12 0 0 0 2.68E+07 1.79E+07 - - - 3.8464 1 221125_WJC_METTL3_EV_vs_WT_F05.18334.18334.3 7.70E-07 22/72 K.LAAAILGGVDQIHIK[136.11]PGAK[136.11].V "sp|P22087|FBRL_HUMAN,tr|M0R299|M0R299_HUMAN,tr|M0R0P1|M0R0P1_HUMAN,tr|M0R1H0|M0R1H0_HUMAN,tr|M0QXL5|M0QXL5_HUMAN,tr|M0R2Q4|M0R2Q4_HUMAN,tr|M0R2B0|M0R2B0_HUMAN,tr|M0R2U2|M0R2U2_HUMAN" 8 1887.1277 1 69397 18334 3 1887.128619 630.0498 rRNA 2'-O-methyltransferase fibrillarin OS=Homo sapiens OX=9606 GN=FBL PE=1 SV=2 8.6 3097.3 - 676700 - - - 0.5039 - 3.57 0.62 - 584.1 1 2 0 0.001 19 0 0 0 1.02E+08 1.02E+08 - - - 8.5786 0.9847 221125_WJC_METTL3_EV_vs_WT_F05.18335.18335.3 0.0015 Dec-44 R.YLYTLVITDK[136.11]EK[136.11].A "sp|P63173|RL38_HUMAN,tr|J3KT73|J3KT73_HUMAN,tr|J3QL01|J3QL01_HUMAN" 3 1500.841 1.48 69398 18335 3 1500.848813 501.2876 60S ribosomal protein L38 OS=Homo sapiens OX=9606 GN=RPL38 PE=1 SV=2 6.07 3097.3 - 1.28E+06 - - - 5.1744 - 1.892 0.39 - 129.6 1 2 1 0.0078 12 0 0 0 2.65E+07 1.79E+07 - - - 4.6534 0.9999 221125_WJC_METTL3_EV_vs_WT_F05.18336.18336.3 0.000118 13/72 R.LQPYNGVALRPWDGNSDDR.V "sp|Q3ZCQ8|TIM50_HUMAN,tr|M0R1Y4|M0R1Y4_HUMAN,tr|M0R0C3|M0R0C3_HUMAN,tr|M0R2F8|M0R2F8_HUMAN,tr|M0R003|M0R003_HUMAN" 5 2172.0348 1.08 69399 18336 3 2172.037558 725.0189 Mitochondrial import inner membrane translocase subunit TIM50 OS=Homo sapiens OX=9606 GN=TIMM50 PE=1 SV=2 4.43 3097.5 - 749584 - - - 1.2564 - 2.365 0.438 - 160.9 1 2 0 0.0027 19 0 0 0 3.43E+07 3.16E+07 - - - 5.5373 0.9998 221125_WJC_METTL3_EV_vs_WT_F05.18338.18338.3 0.000145 16/40 R.TRDELDQFLDK.M "sp|Q14137|BOP1_HUMAN,tr|A0A075B729|A0A075B729_HUMAN" 2 1378.6729 0.86 69401 18338 3 1378.675271 460.5649 Ribosome biogenesis protein BOP1 OS=Homo sapiens OX=9606 GN=BOP1 PE=1 SV=2 4.23 3097.7 - 492311 - - - 1.7495 - 2.696 0.468 - 403.8 1 2 1 0.0024 11 0 0 0 3.63E+06 4.23E+06 - - - 6.5745 0.9996 221125_WJC_METTL3_EV_vs_WT_F05.18339.18339.3 5.30E-09 18/68 R.QKLNPADAPNPVVFVATK.D sp|O94776|MTA2_HUMAN 1 1908.0469 1.25 69402 18339 3 1908.054494 637.0229 Metastasis-associated protein MTA2 OS=Homo sapiens OX=9606 GN=MTA2 PE=1 SV=1 8.59 3097.8 - 415678 - - - 3.981 - 3.339 0.611 - 340.2 1 2 1 0.0076 18 0 0 0 1.28E+07 1.02E+07 - - - 8.3522 0.9825 221125_WJC_METTL3_EV_vs_WT_F05.18340.18340.3 3.75E-10 17/52 W.ELISNASDALDKIR.Y "sp|Q58FF8|H90B2_HUMAN,sp|P08238|HS90B_HUMAN,sp|Q58FF6|H90B4_HUMAN,sp|Q58FF7|H90B3_HUMAN,sp|P14625|ENPL_HUMAN,tr|A0A7P0T917|A0A7P0T917_HUMAN,tr|A0A7P0Z405|A0A7P0Z405_HUMAN,tr|A0A7P0T823|A0A7P0T823_HUMAN,tr|A0A7P0TAE1|A0A7P0TAE1_HUMAN,tr|H0YIV0|H0YIV0_HUMAN,tr|A0A7P0T8R3|A0A7P0T8R3_HUMAN,tr|A0A7P0T885|A0A7P0T885_HUMAN,tr|A0A7P0TAY2|A0A7P0TAY2_HUMAN,tr|A0A087WT78|A0A087WT78_HUMAN,tr|F8W026|F8W026_HUMAN,tr|A0A7P0TBC2|A0A7P0TBC2_HUMAN,tr|A0A7P0TAT8|A0A7P0TAT8_HUMAN" 17 1543.8206 1.42 69403 18340 3 1543.825035 515.6141 Putative heat shock protein HSP 90-beta 2 OS=Homo sapiens OX=9606 GN=HSP90AB2P PE=1 SV=2 4.56 3098 - 367864 - - - 2.8818 - 3.59 0.562 - 488.5 1 1 1 0.0044 14 0 0 0 2.75E+06 1.93E+06 - - - 8.2012 0.9979 221125_WJC_METTL3_EV_vs_WT_F05.18343.18343.3 0.0103 Oct-68 R.QK[136.11]LNPADAPNPVVFVATK[136.11].D sp|O94776|MTA2_HUMAN 1 1924.0753 1.25 69406 18343 3 1924.080661 642.3657 Metastasis-associated protein MTA2 OS=Homo sapiens OX=9606 GN=MTA2 PE=1 SV=1 8.59 3098.3 - 538018 - - - 2.7873 - 2.251 0.389 - 96.7 1 2 1 0.0054 18 0 0 0 1.28E+07 1.02E+07 - - - 4.8959 0.9825 221125_WJC_METTL3_EV_vs_WT_F05.18345.18345.2 0.00235 30-Jul R.AGDWQC[160.03]PNPGC[160.03]GNQNF.A "sp|Q01844|EWS_HUMAN,tr|B0QYK0|B0QYK0_HUMAN,tr|A0A0D9SFL3|A0A0D9SFL3_HUMAN,tr|C9JGE3|C9JGE3_HUMAN" 4 1820.6995 - 69408 18345 2 1820.701005 911.357 RNA-binding protein EWS OS=Homo sapiens OX=9606 GN=EWSR1 PE=1 SV=1 3.8 3098.6 - 199322 - - - 0.8255 - 1.599 0.493 - 102.9 1 1 0 0.0015 16 0 0 0 - - - - - 3.8358 0.9973 221125_WJC_METTL3_EV_vs_WT_F05.18349.18349.3 0.000166 25/76 M.RILSAENIPNLPPGGGLAGK.R "sp|O75688|PPM1B_HUMAN,tr|B8ZZF0|B8ZZF0_HUMAN,tr|A0A3B3IS24|A0A3B3IS24_HUMAN,tr|C9JIR6|C9JIR6_HUMAN" 4 1973.1058 3.7 69411 18349 3 1973.109853 658.7092 Protein phosphatase 1B OS=Homo sapiens OX=9606 GN=PPM1B PE=1 SV=1 8.75 3099.1 - 1.83E+06 - - - 2.0491 - 3.626 0.548 - 639.1 1 1 0 0.004 20 0 0 0 1.58E+08 4.28E+07 - - - 7.7736 1 221125_WJC_METTL3_EV_vs_WT_F05.18352.18352.3 4.69E-07 20/72 K.LAAAILGGVDQIHIKPGAK.V "sp|P22087|FBRL_HUMAN,tr|M0R299|M0R299_HUMAN,tr|M0R0P1|M0R0P1_HUMAN,tr|M0R1H0|M0R1H0_HUMAN,tr|M0QXL5|M0QXL5_HUMAN,tr|M0R2Q4|M0R2Q4_HUMAN,tr|M0R2B0|M0R2B0_HUMAN,tr|M0R2U2|M0R2U2_HUMAN" 8 1871.0993 1 69414 18352 3 1871.100781 624.707 rRNA 2'-O-methyltransferase fibrillarin OS=Homo sapiens OX=9606 GN=FBL PE=1 SV=2 8.6 3099.3 - 941664 - - - 0.8086 - 4.011 0.563 - 604.9 1 2 0 0.0015 19 0 0 0 1.02E+08 1.02E+08 - - - 8.2291 0.9999 221125_WJC_METTL3_EV_vs_WT_F05.18354.18354.3 1.04E-07 17/56 K.AAVEWFDGK[136.11]DFQGSK[136.11].L "sp|Q01844|EWS_HUMAN,tr|B0QYK0|B0QYK0_HUMAN,tr|H7BY36|H7BY36_HUMAN,tr|A0A0D9SFL3|A0A0D9SFL3_HUMAN,tr|C9JGE3|C9JGE3_HUMAN" 5 1699.8177 0.78 69416 18354 3 1699.818218 567.6132 RNA-binding protein EWS OS=Homo sapiens OX=9606 GN=EWSR1 PE=1 SV=1 4.56 3099.5 - 521448 - - - 0.313 - 3.277 0.547 - 460.1 1 2 1 0.0005 15 0 0 0 1.21E+06 1.54E+06 - - - 7.7355 0.9987 221125_WJC_METTL3_EV_vs_WT_F05.18359.18359.4 0.0608 Sep-84 R.TLDELGIHLTKEELK.L sp|Q15029|U5S1_HUMAN 1 1737.9513 1.81 69421 18359 4 1737.950186 435.4951 116 kDa U5 small nuclear ribonucleoprotein component OS=Homo sapiens OX=9606 GN=EFTUD2 PE=1 SV=1 4.83 3100.2 - 239684 - - - -0.6214 - 1.932 0.356 - 43.2 1 2 1 -0.0011 15 0 0 0 4.16E+06 2.29E+06 - - - 2.56 0.997 221125_WJC_METTL3_EV_vs_WT_F05.18366.18366.3 4.58E-06 18/76 M.R[166.11]ILSAENIPNLPPGGGLAGK[136.11].R "sp|O75688|PPM1B_HUMAN,tr|B8ZZF0|B8ZZF0_HUMAN,tr|A0A3B3IS24|A0A3B3IS24_HUMAN,tr|C9JIR6|C9JIR6_HUMAN" 4 1991.1283 3.69 69426 18366 3 1991.125079 664.7167 Protein phosphatase 1B OS=Homo sapiens OX=9606 GN=PPM1B PE=1 SV=1 8.75 3101.1 - 780245 - - - -1.6076 - 3.069 0.516 - 290.5 1 1 0 -0.0032 20 0 0 0 1.59E+08 4.30E+07 - - - 7.0124 0.8076 221125_WJC_METTL3_EV_vs_WT_F05.18370.18370.3 0.0615 Jun-84 R.LIEESSVDEVVVTNTVPHEVQK.L "sp|Q14558|KPRA_HUMAN,tr|B4DP31|B4DP31_HUMAN" 2 2450.2541 0.94 69430 18370 3 2450.260054 817.7586 Phosphoribosyl pyrophosphate synthase-associated protein 1 OS=Homo sapiens OX=9606 GN=PRPSAP1 PE=1 SV=2 4.25 3101.6 - 203547 - - - 2.4504 - 1.276 0.129 - 23.9 1 2 0 0.006 22 0 0 0 5.04E+06 5.38E+06 - - - 0.5544 1 221125_WJC_METTL3_EV_vs_WT_F05.18375.18375.2 2.53E-12 18/24 L.GGVDQIHIK[136.11]PGAK[136.11].V "sp|P22087|FBRL_HUMAN,tr|M0R299|M0R299_HUMAN,tr|M0R0P1|M0R0P1_HUMAN,tr|M0R1H0|M0R1H0_HUMAN,tr|M0QXL5|M0QXL5_HUMAN,tr|M0R2Q4|M0R2Q4_HUMAN,tr|M0R2B0|M0R2B0_HUMAN,tr|M0R2U2|M0R2U2_HUMAN" 8 1334.7641 1.04 69433 18375 2 1334.763589 668.3893 rRNA 2'-O-methyltransferase fibrillarin OS=Homo sapiens OX=9606 GN=FBL PE=1 SV=2 8.6 3102.2 - 715406 - - - -0.4083 - 3.444 0.575 - 1182.9 1 1 0 -0.0005 13 0 0 0 1.84E+07 1.77E+07 - - - 6.4616 0.9335 221125_WJC_METTL3_EV_vs_WT_F05.18386.18386.3 0.114 Oct-44 K.QK[136.11]VDSLLENLEK[136.11].L "sp|P0DMR1|HNRC4_HUMAN,sp|P07910|HNRPC_HUMAN,sp|O60812|HNRC1_HUMAN,sp|B2RXH8|HNRC2_HUMAN,sp|B7ZW38|HNRC3_HUMAN,tr|B4DY08|B4DY08_HUMAN,tr|G3V5V7|G3V5V7_HUMAN,tr|B2R5W2|B2R5W2_HUMAN,tr|G3V4C1|G3V4C1_HUMAN,tr|A0A0G2JPF8|A0A0G2JPF8_HUMAN,tr|A0A0G2JNQ3|A0A0G2JNQ3_HUMAN,tr|G3V576|G3V576_HUMAN,tr|G3V2D6|G3V2D6_HUMAN,tr|G3V4W0|G3V4W0_HUMAN,tr|G3V2Q1|G3V2Q1_HUMAN" 15 1430.7952 1.45 69442 18386 3 1430.790334 477.939 Heterogeneous nuclear ribonucleoprotein C-like 4 OS=Homo sapiens OX=9606 GN=HNRNPCL4 PE=3 SV=1 4.68 3103.5 - 2.44E+06 - - - -3.3729 - 1.929 0.195 - 195 1 2 1 -0.0048 12 0 0 0 2.94E+09 2.02E+09 - - - 2.5338 0.9925 221125_WJC_METTL3_EV_vs_WT_F05.18388.18388.2 0.00139 22-Nov K.QKVDSLLENLEK.L "sp|P0DMR1|HNRC4_HUMAN,sp|P07910|HNRPC_HUMAN,sp|O60812|HNRC1_HUMAN,sp|B2RXH8|HNRC2_HUMAN,sp|B7ZW38|HNRC3_HUMAN,tr|B4DY08|B4DY08_HUMAN,tr|G3V5V7|G3V5V7_HUMAN,tr|B2R5W2|B2R5W2_HUMAN,tr|G3V4C1|G3V4C1_HUMAN,tr|A0A0G2JPF8|A0A0G2JPF8_HUMAN,tr|A0A0G2JNQ3|A0A0G2JNQ3_HUMAN,tr|G3V576|G3V576_HUMAN,tr|G3V2D6|G3V2D6_HUMAN,tr|G3V4W0|G3V4W0_HUMAN,tr|G3V2Q1|G3V2Q1_HUMAN" 15 1414.7668 1.47 69444 18388 2 1414.762983 708.3907 Heterogeneous nuclear ribonucleoprotein C-like 4 OS=Homo sapiens OX=9606 GN=HNRNPCL4 PE=3 SV=1 4.68 3103.8 - 685975 - - - -2.6697 - 2.174 0.413 - 330.1 1 2 1 -0.0038 12 0 0 0 7.03E+08 4.78E+08 - - - 4.1335 0.9926 221125_WJC_METTL3_EV_vs_WT_F05.18389.18389.2 2.27E-05 13/22 K.QK[136.11]VDSLLENLEK[136.11].L "sp|P0DMR1|HNRC4_HUMAN,sp|P07910|HNRPC_HUMAN,sp|O60812|HNRC1_HUMAN,sp|B2RXH8|HNRC2_HUMAN,sp|B7ZW38|HNRC3_HUMAN,tr|B4DY08|B4DY08_HUMAN,tr|G3V5V7|G3V5V7_HUMAN,tr|B2R5W2|B2R5W2_HUMAN,tr|G3V4C1|G3V4C1_HUMAN,tr|A0A0G2JPF8|A0A0G2JPF8_HUMAN,tr|A0A0G2JNQ3|A0A0G2JNQ3_HUMAN,tr|G3V576|G3V576_HUMAN,tr|G3V2D6|G3V2D6_HUMAN,tr|G3V4W0|G3V4W0_HUMAN,tr|G3V2Q1|G3V2Q1_HUMAN" 15 1430.7952 1.47 69445 18389 2 1430.790406 716.4049 Heterogeneous nuclear ribonucleoprotein C-like 4 OS=Homo sapiens OX=9606 GN=HNRNPCL4 PE=3 SV=1 4.68 3103.9 - 614933 - - - -3.3226 - 2.247 0.506 - 516.4 1 2 1 -0.0048 12 0 0 0 7.03E+08 4.78E+08 - - - 4.907 0.9997 221125_WJC_METTL3_EV_vs_WT_F05.18394.18394.3 3.56E-07 Oct-84 R.LIEESSVDEVVVTNTVPHEVQK[136.11].L "sp|Q14558|KPRA_HUMAN,tr|B4DP31|B4DP31_HUMAN" 2 2458.2683 0.94 69448 18394 3 2458.26117 820.43 Phosphoribosyl pyrophosphate synthase-associated protein 1 OS=Homo sapiens OX=9606 GN=PRPSAP1 PE=1 SV=2 4.25 3104.6 - 335041 - - - -2.8801 - 1.902 0.478 - 61.1 1 2 0 -0.0071 22 0 0 0 5.04E+06 5.38E+06 - - - 5.3915 1 221125_WJC_METTL3_EV_vs_WT_F05.18395.18395.3 8.33E-12 27/84 K.GSSPLPTATTPKPLIPTEASIR.V "sp|Q9BUK6|MSTO1_HUMAN,tr|A0A3B3IUD2|A0A3B3IUD2_HUMAN" 2 2233.2318 1.85 69449 18395 3 2233.232591 745.4179 Protein misato homolog 1 OS=Homo sapiens OX=9606 GN=MSTO1 PE=1 SV=1 8.75 3104.7 - 1.40E+06 - - - 0.3551 - 3.74 0.618 - 609.9 1 2 0 0.0008 22 0 0 0 9.08E+07 4.92E+07 - - - 8.5572 0.997 221125_WJC_METTL3_EV_vs_WT_F05.18398.18398.4 5.76E-05 17/108 K.LTDISVTDPEKYPHMLSVK.N sp|Q9Y333|LSM2_HUMAN 1 2172.1137 3.59 69450 18398 4 2172.108068 544.0357 U6 snRNA-associated Sm-like protein LSm2 OS=Homo sapiens OX=9606 GN=LSM2 PE=1 SV=1 5.38 3105.1 - 519711 - - - -2.5731 - 2.901 0.34 - 171.9 1 2 1 -0.0056 19 0 0 0 1.87E+07 5.22E+06 - - - 2.5441 0.9919 221125_WJC_METTL3_EV_vs_WT_F05.18400.18400.2 2.65E-09 26-Nov K.DHTPSQELALTQSV.G "sp|Q86U44|MTA70_HUMAN,tr|H0YFV6|H0YFV6_HUMAN" 2 1524.742 - 69452 18400 2 1524.739602 763.3783 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 4.35 3105.3 - 1.17E+06 - - - -1.5734 - 2.449 0.591 - 401 1 1 0 -0.0024 14 0 0 0 - - - - - 5.653 0.9999 221125_WJC_METTL3_EV_vs_WT_F05.18404.18404.4 2.15E-07 16/78 K.LHNMIVDLDNVVKK.V "sp|Q16891|MIC60_HUMAN,tr|B9A067|B9A067_HUMAN,tr|C9J406|C9J406_HUMAN,tr|H7C463|H7C463_HUMAN" 4 1636.8971 1.27 69454 18404 4 1636.890283 410.2315 MICOS complex subunit MIC60 OS=Homo sapiens OX=9606 GN=IMMT PE=1 SV=1 6.75 3105.9 - 637764 - - - -4.1414 - 3.047 0.572 - 305.8 1 2 0 -0.0068 14 0 0 0 3.40E+07 2.68E+07 - - - 4.6083 1 221125_WJC_METTL3_EV_vs_WT_F05.18406.18406.3 7.00E-10 19/84 K.GSSPLPTATTPK[136.11]PLIPTEASIR[166.11].V "sp|Q9BUK6|MSTO1_HUMAN,tr|A0A3B3IUD2|A0A3B3IUD2_HUMAN" 2 2251.2543 1.84 69455 18406 3 2251.252422 751.4254 Protein misato homolog 1 OS=Homo sapiens OX=9606 GN=MSTO1 PE=1 SV=1 8.75 3106.1 - 972192 - - - -0.82 - 3.335 0.572 - 269 1 2 0 -0.0018 22 0 0 0 9.08E+07 4.94E+07 - - - 7.7723 0.9999 221125_WJC_METTL3_EV_vs_WT_F05.18407.18407.4 8.30E-10 16/78 K.LHNMIVDLDNVVK[136.11]K[136.11].V "sp|Q16891|MIC60_HUMAN,tr|B9A067|B9A067_HUMAN,tr|C9J406|C9J406_HUMAN,tr|H7C463|H7C463_HUMAN" 4 1652.9255 1.27 69456 18407 4 1652.919178 414.2386 MICOS complex subunit MIC60 OS=Homo sapiens OX=9606 GN=IMMT PE=1 SV=1 6.75 3106.2 - 760188 - - - -3.8017 - 2.558 0.586 - 255.8 1 2 0 -0.0063 14 0 0 0 3.40E+07 2.68E+07 - - - 4.6666 1 221125_WJC_METTL3_EV_vs_WT_F05.18408.18408.3 8.76E-09 20/52 K.LHNMIVDLDNVVKK.V "sp|Q16891|MIC60_HUMAN,tr|B9A067|B9A067_HUMAN,tr|C9J406|C9J406_HUMAN,tr|H7C463|H7C463_HUMAN" 4 1636.8971 1.37 69457 18408 3 1636.891975 546.6396 MICOS complex subunit MIC60 OS=Homo sapiens OX=9606 GN=IMMT PE=1 SV=1 6.75 3106.3 - 785219 - - - -3.1077 - 3.117 0.628 - 548.3 1 2 0 -0.0051 14 0 0 0 3.78E+07 2.77E+07 - - - 8.5614 0.9984 221125_WJC_METTL3_EV_vs_WT_F05.18409.18409.3 0.000601 13/92 K.TAPPVTNNSEIQASEVLVAADK[136.11]EK[136.11].V sp|Q96T58|MINT_HUMAN 1 2526.3148 2.34 69458 18409 3 2526.311652 843.1122 Msx2-interacting protein OS=Homo sapiens OX=9606 GN=SPEN PE=1 SV=1 4.41 3106.5 - 727356 - - - -1.2508 - 2.213 0.341 - 121.2 1 2 1 -0.0032 24 0 0 0 2.43E+07 1.04E+07 - - - 4.1859 1 221125_WJC_METTL3_EV_vs_WT_F05.18410.18410.2 1.72E-05 15/28 K.AAVEWFDGK[136.11]DFQGSK[136.11].L "sp|Q01844|EWS_HUMAN,tr|B0QYK0|B0QYK0_HUMAN,tr|H7BY36|H7BY36_HUMAN,tr|A0A0D9SFL3|A0A0D9SFL3_HUMAN,tr|C9JGE3|C9JGE3_HUMAN" 5 1699.8177 0.59 69459 18410 2 1699.811078 850.9161 RNA-binding protein EWS OS=Homo sapiens OX=9606 GN=EWSR1 PE=1 SV=1 4.56 3106.6 - 633411 - - - -3.8875 - 3.122 0.557 - 859.3 1 2 1 -0.0066 15 0 0 0 7.16E+07 1.21E+08 - - - 5.9519 0.9217 221125_WJC_METTL3_EV_vs_WT_F05.18415.18415.3 0.289 Oct-44 K.QKVDSLLENLEK.L "sp|P0DMR1|HNRC4_HUMAN,sp|P07910|HNRPC_HUMAN,sp|O60812|HNRC1_HUMAN,sp|B2RXH8|HNRC2_HUMAN,sp|B7ZW38|HNRC3_HUMAN,tr|B4DY08|B4DY08_HUMAN,tr|G3V5V7|G3V5V7_HUMAN,tr|B2R5W2|B2R5W2_HUMAN,tr|G3V4C1|G3V4C1_HUMAN,tr|A0A0G2JPF8|A0A0G2JPF8_HUMAN,tr|A0A0G2JNQ3|A0A0G2JNQ3_HUMAN,tr|G3V576|G3V576_HUMAN,tr|G3V2D6|G3V2D6_HUMAN,tr|G3V4W0|G3V4W0_HUMAN,tr|G3V2Q1|G3V2Q1_HUMAN" 15 1414.7668 1.45 69460 18415 3 1414.764339 472.5962 Heterogeneous nuclear ribonucleoprotein C-like 4 OS=Homo sapiens OX=9606 GN=HNRNPCL4 PE=3 SV=1 4.68 3107.3 - 5.16E+07 - - - -1.7112 - 1.872 0.126 - 199.3 1 2 1 -0.0024 12 0 0 0 2.94E+09 2.02E+09 - - - 1.6821 0.9999 221125_WJC_METTL3_EV_vs_WT_F05.18416.18416.4 3.00E-08 17/108 R.LKVGLQVVAVKAPGFGDNR.K "sp|P10809|CH60_HUMAN,tr|A0A7I2V2X6|A0A7I2V2X6_HUMAN,tr|A0A7I2YQK6|A0A7I2YQK6_HUMAN,tr|A0A7I2V599|A0A7I2V599_HUMAN,tr|A0A7I2V5M1|A0A7I2V5M1_HUMAN" 5 1967.1316 1.18 69461 18416 4 1967.127093 492.7902 "60 kDa heat shock protein, mitochondrial OS=Homo sapiens OX=9606 GN=HSPD1 PE=1 SV=2" 9.99 3107.4 - 649956 - - - -2.3064 - 2.643 0.559 - 173.3 1 2 2 -0.0045 19 0 0 0 3.47E+07 2.94E+07 - - - 4.4191 0.9999 221125_WJC_METTL3_EV_vs_WT_F05.18418.18418.3 3.65E-06 13/52 K.K[136.11]NPEVPVNFAEFSK[136.11].K "sp|O15347|HMGB3_HUMAN,tr|E9PES6|E9PES6_HUMAN,tr|E7EQU1|E7EQU1_HUMAN,tr|E7ES08|E7ES08_HUMAN" 4 1620.8483 0.28 69463 18418 3 1620.84426 541.29 High mobility group protein B3 OS=Homo sapiens OX=9606 GN=HMGB3 PE=1 SV=4 6.14 3107.6 - 1.09E+06 - - - -2.4666 - 2.498 0.487 - 249.9 1 2 0 -0.004 14 0 0 0 2.30E+07 8.11E+07 - - - 6.4014 1 221125_WJC_METTL3_EV_vs_WT_F05.18419.18419.3 4.91E-05 16/68 K.LHIIEVGTPPTGNQPFPK.K "sp|Q00610|CLH1_HUMAN,tr|A0A087WVQ6|A0A087WVQ6_HUMAN" 2 1944.0469 0.91 69464 18419 3 1944.045709 649.0229 Clathrin heavy chain 1 OS=Homo sapiens OX=9606 GN=CLTC PE=1 SV=5 6.75 3107.7 - 612423 - - - -0.6116 - 2.753 0.438 - 343.7 1 2 0 -0.0012 18 0 0 0 1.61E+07 1.77E+07 - - - 5.9446 0.9999 221125_WJC_METTL3_EV_vs_WT_F05.18420.18420.3 2.52E-05 14/68 K.LHIIEVGTPPTGNQPFPK[136.11].K "sp|Q00610|CLH1_HUMAN,tr|A0A087WVQ6|A0A087WVQ6_HUMAN" 2 1952.0611 0.92 69465 18420 3 1952.0561 651.6943 Clathrin heavy chain 1 OS=Homo sapiens OX=9606 GN=CLTC PE=1 SV=5 6.75 3107.9 - 483972 - - - -2.5604 - 3.06 0.488 - 270.5 1 2 0 -0.005 18 0 0 0 1.61E+07 1.75E+07 - - - 6.7643 0.9999 221125_WJC_METTL3_EV_vs_WT_F05.18426.18426.3 3.23E-05 22/92 K.TAPPVTNNSEIQASEVLVAADKEK.V sp|Q96T58|MINT_HUMAN 1 2510.2864 2.34 69469 18426 3 2510.280622 837.7694 Msx2-interacting protein OS=Homo sapiens OX=9606 GN=SPEN PE=1 SV=1 4.41 3108.6 - 2.01E+06 - - - -2.3065 - 3.67 0.543 - 391 1 2 1 -0.0058 24 0 0 0 2.43E+07 1.04E+07 - - - 7.6121 1 221125_WJC_METTL3_EV_vs_WT_F05.18427.18427.3 4.99E-10 20/48 K.NDTEFQLHIPVQR.Q "sp|Q7Z353|HDX_HUMAN,tr|E2QRN0|E2QRN0_HUMAN" 2 1595.8056 1.26 69470 18427 3 1595.801952 532.9425 Highly divergent homeobox OS=Homo sapiens OX=9606 GN=HDX PE=1 SV=1 5.32 3108.7 - 830301 - - - -2.2891 - 3.051 0.605 - 529.8 1 2 0 -0.0037 13 0 0 0 2.78E+07 2.21E+07 - - - 8.3085 0.9969 221125_WJC_METTL3_EV_vs_WT_F05.18428.18428.3 2.99E-07 17/56 R.K[136.11]GFNEGLWEIDNNPK[136.11].V sp|O75475|PSIP1_HUMAN 1 1775.8813 0.82 69471 18428 3 1776.878509 592.9677 PC4 and SFRS1-interacting protein OS=Homo sapiens OX=9606 GN=PSIP1 PE=1 SV=1 4.68 3108.9 - 732848 - - - 561.5015 - 2.668 0.557 - 346.8 1 2 0 0.9972 15 0 0 0 1.22E+07 1.49E+07 - - - 7.0344 1 221125_WJC_METTL3_EV_vs_WT_F05.18433.18433.4 2.60E-15 22/108 R.LK[136.11]VGLQVVAVK[136.11]APGFGDNR[166.11].K "sp|P10809|CH60_HUMAN,tr|A0A7I2V2X6|A0A7I2V2X6_HUMAN,tr|A0A7I2YQK6|A0A7I2YQK6_HUMAN,tr|A0A7I2V599|A0A7I2V599_HUMAN,tr|A0A7I2V5M1|A0A7I2V5M1_HUMAN" 5 1993.1683 1.18 69474 18433 4 1993.165701 499.2994 "60 kDa heat shock protein, mitochondrial OS=Homo sapiens OX=9606 GN=HSPD1 PE=1 SV=2" 9.99 3109.5 - 1.14E+06 - - - -1.304 - 3.818 0.671 - 310.9 1 2 2 -0.0026 19 0 0 0 3.47E+07 2.94E+07 - - - 5.5189 1 221125_WJC_METTL3_EV_vs_WT_F05.18440.18440.2 1.37E-08 14/28 K.AAVEWFDGKDFQGSK.L "sp|Q01844|EWS_HUMAN,tr|B0QYK0|B0QYK0_HUMAN,tr|H7BY36|H7BY36_HUMAN,tr|A0A0D9SFL3|A0A0D9SFL3_HUMAN,tr|C9JGE3|C9JGE3_HUMAN" 5 1683.7893 0.59 69479 18440 2 1683.786664 842.9019 RNA-binding protein EWS OS=Homo sapiens OX=9606 GN=EWSR1 PE=1 SV=1 4.56 3110.4 - 3.49E+06 - - - -1.5572 - 2.993 0.545 - 727.7 1 2 1 -0.0026 15 0 0 0 7.16E+07 1.21E+08 - - - 5.7608 1 221125_WJC_METTL3_EV_vs_WT_F05.18442.18442.3 1.18E-07 17/52 K.KNPEVPVNFAEFSK.K "sp|O15347|HMGB3_HUMAN,tr|E9PES6|E9PES6_HUMAN,tr|E7EQU1|E7EQU1_HUMAN,tr|E7ES08|E7ES08_HUMAN" 4 1604.8199 0.28 69481 18442 3 1604.818426 535.9472 High mobility group protein B3 OS=Homo sapiens OX=9606 GN=HMGB3 PE=1 SV=4 6.14 3110.6 - 1.21E+06 - - - -0.8923 - 2.577 0.594 - 347.3 1 2 0 -0.0014 14 0 0 0 2.30E+07 8.11E+07 - - - 7.6778 0.9999 221125_WJC_METTL3_EV_vs_WT_F05.18446.18446.3 1.56E-05 13/56 R.KGFNEGLWEIDNNPK.V sp|O75475|PSIP1_HUMAN 1 1759.8529 0.82 69485 18446 3 1759.848702 587.6249 PC4 and SFRS1-interacting protein OS=Homo sapiens OX=9606 GN=PSIP1 PE=1 SV=1 4.68 3111.2 - 788242 - - - -2.4133 - 2.461 0.497 - 163.2 1 2 0 -0.0042 15 0 0 0 1.22E+07 1.49E+07 - - - 6.4298 1 221125_WJC_METTL3_EV_vs_WT_F05.18451.18451.3 9.80E-11 19/76 K.IWEQIQPDLHTNDEC[160.03]VATYK.G sp|Q12904|AIMP1_HUMAN 1 2459.1427 1.27 69488 18451 3 2459.142045 820.7215 Aminoacyl tRNA synthase complex-interacting multifunctional protein 1 OS=Homo sapiens OX=9606 GN=AIMP1 PE=1 SV=2 4.31 3111.8 - 1.25E+06 - - - -0.2765 - 3.971 0.62 - 429.5 1 2 0 -0.0007 20 0 0 0 2.57E+07 2.02E+07 - - - 8.7977 0.897 221125_WJC_METTL3_EV_vs_WT_F05.18453.18453.2 1.08E-06 14/24 A.VEWFDGK[136.11]DFQGSK[136.11].L "sp|Q01844|EWS_HUMAN,tr|B0QYK0|B0QYK0_HUMAN,tr|H7BY36|H7BY36_HUMAN,tr|A0A0D9SFL3|A0A0D9SFL3_HUMAN,tr|C9JGE3|C9JGE3_HUMAN" 5 1557.7435 0.17 69490 18453 2 1557.740629 779.879 RNA-binding protein EWS OS=Homo sapiens OX=9606 GN=EWSR1 PE=1 SV=1 4.56 3112.1 - 1.12E+06 - - - -1.8161 - 2.534 0.548 - 430.8 1 1 1 -0.0028 13 0 0 0 5.14E+06 2.96E+07 - - - 5.474 0.9988 221125_WJC_METTL3_EV_vs_WT_F05.18455.18455.3 0.186 18/48 K.ENFPNFLSAC[160.03]DKK.G "sp|Q86SG5|S1A7A_HUMAN,sp|P31151|S10A7_HUMAN" 2 1568.7293 1465.28 69492 18455 3 1568.719425 523.9171 Protein S100-A7A OS=Homo sapiens OX=9606 GN=S100A7A PE=1 SV=3 6.16 3112.3 - 828953 - - - -6.3128 - 2.833 0.463 - 352 1 2 0 -0.0099 13 0 0 0 1.25E+08 8.54E+04 - - - 6.5226 0.9924 221125_WJC_METTL3_EV_vs_WT_F05.18456.18456.2 0.000379 22-Oct K.QKVDSLLENLEK[136.11].L "sp|P0DMR1|HNRC4_HUMAN,sp|P07910|HNRPC_HUMAN,sp|O60812|HNRC1_HUMAN,sp|B2RXH8|HNRC2_HUMAN,sp|B7ZW38|HNRC3_HUMAN,tr|B4DY08|B4DY08_HUMAN,tr|G3V5V7|G3V5V7_HUMAN,tr|B2R5W2|B2R5W2_HUMAN,tr|G3V4C1|G3V4C1_HUMAN,tr|A0A0G2JPF8|A0A0G2JPF8_HUMAN,tr|A0A0G2JNQ3|A0A0G2JNQ3_HUMAN,tr|G3V576|G3V576_HUMAN,tr|G3V2D6|G3V2D6_HUMAN,tr|G3V4W0|G3V4W0_HUMAN,tr|G3V2Q1|G3V2Q1_HUMAN" 15 1422.781 - 69493 18456 2 1422.777641 712.3978 Heterogeneous nuclear ribonucleoprotein C-like 4 OS=Homo sapiens OX=9606 GN=HNRNPCL4 PE=3 SV=1 4.68 3112.5 - 596561 - - - -2.3328 - 2.144 0.373 - 286.6 1 2 1 -0.0033 12 0 0 0 - - - - - 3.8017 0.9997 221125_WJC_METTL3_EV_vs_WT_F05.18461.18461.3 4.71E-05 17/48 R.KQELAETLANLER.Q sp|Q9HAF1|EAF6_HUMAN 1 1513.81 2.02 69496 18461 3 1513.803835 505.6106 Chromatin modification-related protein MEAF6 OS=Homo sapiens OX=9606 GN=MEAF6 PE=1 SV=1 4.79 3113.1 - 1.43E+06 - - - -4.0864 - 3.356 0.411 - 497.6 1 2 0 -0.0062 13 0 0 0 5.12E+07 2.54E+07 - - - 6.4032 0.9781 221125_WJC_METTL3_EV_vs_WT_F05.18463.18463.3 7.18E-05 Dec-60 K.ASEVEEILDGNDEK[136.11]YK[136.11].A "sp|Q12824|SNF5_HUMAN,tr|A0A2R8Y5N5|A0A2R8Y5N5_HUMAN,tr|A0A2R8YEE8|A0A2R8YEE8_HUMAN,tr|A0A0U1RQQ2|A0A0U1RQQ2_HUMAN,tr|C9JTA6|C9JTA6_HUMAN,tr|B5MCL5|B5MCL5_HUMAN,tr|A0A0U1RRB8|A0A0U1RRB8_HUMAN,tr|A0A0G2JRV3|A0A0G2JRV3_HUMAN,tr|G5E975|G5E975_HUMAN,tr|A0A0G2JSE9|A0A0G2JSE9_HUMAN" 10 1853.8866 2.03 69498 18463 3 1853.875528 618.9695 SWI\SNF-related matrix-associated actin-dependent regulator of chromatin subfamily B member 1 OS=Homo sapiens OX=9606 GN=SMARCB1 PE=1 SV=2 4.08 3113.3 - 521937 - - - -5.947 - 2.443 0.355 - 210.8 1 2 1 -0.011 16 0 0 0 1.00E+07 4.91E+06 - - - 4.7867 0.9991 221125_WJC_METTL3_EV_vs_WT_F05.18466.18466.3 0.000984 Dec-56 K.TK[136.11]DGQILPVPNVVVR[166.11].D sp|Q9P258|RCC2_HUMAN 1 1651.974 0.56 69499 18466 3 1651.973638 551.6653 Protein RCC2 OS=Homo sapiens OX=9606 GN=RCC2 PE=1 SV=2 8.41 3113.7 - 785072 - - - -0.2258 - 2.332 0.34 - 191.2 1 2 1 -0.0004 15 0 0 0 5.33E+06 9.54E+06 - - - 4.54 1 221125_WJC_METTL3_EV_vs_WT_F05.18467.18467.3 0.00389 17/68 R.QISRPSAAGINLMIGSTR.Y sp|Q08211|DHX9_HUMAN 1 1871.0047 0.71 69500 18467 3 1871.004803 624.6755 ATP-dependent RNA helicase A OS=Homo sapiens OX=9606 GN=DHX9 PE=1 SV=4 12 3113.9 - 701221 - - - 0.047 - 3.021 0.448 - 295.4 1 2 0 0.0001 18 0 0 0 1.20E+07 1.69E+07 - - - 6.2878 1 221125_WJC_METTL3_EV_vs_WT_F05.18468.18468.4 6.52E-05 18/108 R.SDTLIKPVLVKPEGVLVEK.T "sp|A8K2U0|A2ML1_HUMAN,tr|H0YGG5|H0YGG5_HUMAN" 2 2063.2242 999 69501 18468 4 2063.221328 516.8133 Alpha-2-macroglobulin-like protein 1 OS=Homo sapiens OX=9606 GN=A2ML1 PE=1 SV=3 5.9 3114 - 1.09E+06 - - - -1.3886 - 3.35 0.523 - 258.9 1 2 0 -0.0029 19 0 0 0 1.13E+07 0.00E+00 - - - 4.1864 1 221125_WJC_METTL3_EV_vs_WT_F05.18471.18471.3 3.77E-08 16/72 R.SDTLIKPVLVKPEGVLVEK.T "sp|A8K2U0|A2ML1_HUMAN,tr|H0YGG5|H0YGG5_HUMAN" 2 2063.2242 999 69504 18471 3 2063.229548 688.7487 Alpha-2-macroglobulin-like protein 1 OS=Homo sapiens OX=9606 GN=A2ML1 PE=1 SV=3 5.9 3114.4 - 502308 - - - 2.5955 - 2.957 0.609 - 153.4 1 2 0 0.0054 19 0 0 0 2.79E+06 0.00E+00 - - - 7.9919 0.9999 221125_WJC_METTL3_EV_vs_WT_F05.18477.18477.3 1.24E-08 16/56 K.AAVEWFDGKDFQGSK.L "sp|Q01844|EWS_HUMAN,tr|B0QYK0|B0QYK0_HUMAN,tr|H7BY36|H7BY36_HUMAN,tr|A0A0D9SFL3|A0A0D9SFL3_HUMAN,tr|C9JGE3|C9JGE3_HUMAN" 5 1683.7893 0.65 69508 18477 3 1683.788095 562.2704 RNA-binding protein EWS OS=Homo sapiens OX=9606 GN=EWSR1 PE=1 SV=1 4.56 3115.1 - 5.66E+07 - - - -0.7073 - 3.453 0.559 - 463.8 1 2 1 -0.0012 15 0 0 0 1.06E+09 1.63E+09 - - - 8.0056 1 221125_WJC_METTL3_EV_vs_WT_F05.18478.18478.3 3.65E-06 15/48 R.K[136.11]QELAETLANLER[166.11].Q sp|Q9HAF1|EAF6_HUMAN 1 1531.8325 2.06 69509 18478 3 1531.834616 511.6181 Chromatin modification-related protein MEAF6 OS=Homo sapiens OX=9606 GN=MEAF6 PE=1 SV=1 4.79 3115.2 - 1.96E+06 - - - 1.3872 - 2.958 0.486 - 363 1 2 0 0.0021 13 0 0 0 5.24E+07 2.54E+07 - - - 6.8983 1 221125_WJC_METTL3_EV_vs_WT_F05.18480.18480.3 1.09E-09 19/80 R.LSPPSSSAASSYSFSDLNSTR.G "sp|P50402|EMD_HUMAN,tr|A0A804HLA2|A0A804HLA2_HUMAN,tr|A0A804HIV7|A0A804HIV7_HUMAN" 3 2159.9971 0.98 69511 18480 3 2159.991655 721.0063 Emerin OS=Homo sapiens OX=9606 GN=EMD PE=1 SV=1 5.84 3115.5 - 838189 - - - -2.5241 - 3.616 0.646 - 363.6 1 2 0 -0.0055 21 0 0 0 1.63E+07 1.66E+07 - - - 8.8224 1 221125_WJC_METTL3_EV_vs_WT_F05.18482.18482.2 3.86E-10 14/30 R.SNASLTNNQNLIQSLK.E sp|P12270|TPR_HUMAN 1 1743.9115 2.23 69513 18482 2 1743.911722 872.963 Nucleoprotein TPR OS=Homo sapiens OX=9606 GN=TPR PE=1 SV=3 8.47 3115.7 - 713381 - - - 0.1124 - 3.228 0.565 - 628.8 1 2 0 0.0002 16 0 0 0 7.07E+06 3.17E+06 - - - 6.0951 0.9999 221125_WJC_METTL3_EV_vs_WT_F05.18487.18487.3 3.91E-05 Nov-60 R.GAGNQYNYIGYLDYK[136.11]K[136.11].E sp|Q68CQ7|GL8D1_HUMAN 1 1881.9232 2.8 69518 18487 3 1881.920336 628.315 Glycosyltransferase 8 domain-containing protein 1 OS=Homo sapiens OX=9606 GN=GLT8D1 PE=1 SV=2 8.34 3116.4 - 306092 - - - -1.5293 - 1.784 0.476 - 83 1 2 0 -0.0029 16 0 0 0 5.87E+06 2.09E+06 - - - 5.3314 1 221125_WJC_METTL3_EV_vs_WT_F05.18489.18489.2 1.26E-11 15/30 R.SNASLTNNQNLIQSLK[136.11].E sp|P12270|TPR_HUMAN 1 1751.9257 2.23 69520 18489 2 1751.920039 876.9701 Nucleoprotein TPR OS=Homo sapiens OX=9606 GN=TPR PE=1 SV=3 8.47 3116.6 - 268989 - - - -3.2461 - 3.303 0.622 - 837.9 1 2 0 -0.0057 16 0 0 0 7.07E+06 3.17E+06 - - - 6.5709 1 221125_WJC_METTL3_EV_vs_WT_F05.18492.18492.2 3.64E-07 17/28 K.QNASLQAAITDAEQR.G sp|Q8N1N4|K2C78_HUMAN 1 1614.7962 999 69521 18492 2 1614.791924 808.4054 "Keratin, type II cytoskeletal 78 OS=Homo sapiens OX=9606 GN=KRT78 PE=1 SV=2" 4.37 3117.1 - 2.50E+06 - - - -2.6245 - 3.515 0.617 - 1315.6 1 2 0 -0.0042 15 0 0 0 2.23E+07 0.00E+00 - - - 6.6873 0.9997 221125_WJC_METTL3_EV_vs_WT_F05.18493.18493.3 0.0102 13/68 R.QISR[166.11]PSAAGINLMIGSTR[166.11].Y sp|Q08211|DHX9_HUMAN 1 1891.0213 0.73 69522 18493 3 1891.019438 631.3477 ATP-dependent RNA helicase A OS=Homo sapiens OX=9606 GN=DHX9 PE=1 SV=4 12 3117.1 - 1.51E+06 - - - -0.9609 - 2.345 0.327 - 117.4 1 2 0 -0.0018 18 0 0 0 1.19E+07 1.64E+07 - - - 4.3075 1 221125_WJC_METTL3_EV_vs_WT_F05.18495.18495.3 4.93E-09 16/64 K.VHSAVITVPAYFNDSQR[166.11].Q sp|P54652|HSP72_HUMAN 1 1912.9671 0.11 69524 18495 3 1912.965214 638.663 Heat shock-related 70 kDa protein 2 OS=Homo sapiens OX=9606 GN=HSPA2 PE=1 SV=1 6.71 3117.4 - 803779 - - - -0.976 - 3.247 0.653 - 499.7 1 2 0 -0.0019 17 0 0 0 2.16E+06 1.98E+07 - - - 8.7951 0.9998 221125_WJC_METTL3_EV_vs_WT_F05.18496.18496.2 0.000168 14/24 R.KQELAETLANLER.Q sp|Q9HAF1|EAF6_HUMAN 1 1513.81 999 69525 18496 2 1513.807243 757.9123 Chromatin modification-related protein MEAF6 OS=Homo sapiens OX=9606 GN=MEAF6 PE=1 SV=1 4.79 3117.5 - 722807 - - - -1.8351 - 2.81 0.508 - 766.9 1 2 0 -0.0028 13 0 0 0 6.17E+06 0.00E+00 - - - 5.4439 0.9776 221125_WJC_METTL3_EV_vs_WT_F05.18497.18497.3 0.183 Sep-56 K.NVTQIEPFC[160.03]LETDR[166.11]R[166.11].G sp|Q9ULW0|TPX2_HUMAN 1 1896.9267 0.29 69526 18497 3 1896.923271 633.3162 Targeting protein for Xklp2 OS=Homo sapiens OX=9606 GN=TPX2 PE=1 SV=2 4.68 3117.6 - 469864 - - - -1.8003 - 1.453 0.186 - 52.8 1 2 0 -0.0034 15 0 0 0 1.45E+06 4.95E+06 - - - 1.5877 0.9997 221125_WJC_METTL3_EV_vs_WT_F05.18500.18500.3 0.0213 Oct-48 K.KGLTPSQIGVILR.D "sp|P62277|RS13_HUMAN,tr|J3KMX5|J3KMX5_HUMAN" 2 1380.8453 0.89 69529 18500 3 1380.845667 461.289 40S ribosomal protein S13 OS=Homo sapiens OX=9606 GN=RPS13 PE=1 SV=2 11 3118 - 289129 - - - 0.2766 - 1.816 0.358 - 140.4 1 2 0 0.0004 13 0 0 0 2.67E+06 3.00E+06 - - - 4.1489 0.9999 221125_WJC_METTL3_EV_vs_WT_F05.18509.18509.3 8.06E-08 19/68 K.EDLDK[136.11]VEPAVIEAQNAVK[136.11].S "sp|Q14204|DYHC1_HUMAN,tr|A0A7P0T8N2|A0A7P0T8N2_HUMAN,tr|A0A7P0T9C4|A0A7P0T9C4_HUMAN,tr|A0A7P0TBJ7|A0A7P0TBJ7_HUMAN,tr|A0A7P0T9K2|A0A7P0T9K2_HUMAN,tr|A0A2R8Y706|A0A2R8Y706_HUMAN,tr|A0A7P0T916|A0A7P0T916_HUMAN,tr|A0A7P0TB75|A0A7P0TB75_HUMAN,tr|A0A7P0T8W5|A0A7P0T8W5_HUMAN,tr|A0A7P0TAF3|A0A7P0TAF3_HUMAN,tr|A0A7P0T9F1|A0A7P0T9F1_HUMAN,tr|A0A7P0TAW9|A0A7P0TAW9_HUMAN,tr|A0A7P0TA13|A0A7P0TA13_HUMAN,tr|A0A7P0T7V5|A0A7P0T7V5_HUMAN,tr|A0A7P0T9R4|A0A7P0T9R4_HUMAN,tr|A0A2R8Y5T0|A0A2R8Y5T0_HUMAN,tr|A0A2R8YFZ7|A0A2R8YFZ7_HUMAN,tr|A0A7P0T825|A0A7P0T825_HUMAN,tr|A0A2R8Y6H2|A0A2R8Y6H2_HUMAN,tr|A0A7P0TAM4|A0A7P0TAM4_HUMAN" 20 1983.0495 1.23 69536 18509 3 1983.049024 662.0238 Cytoplasmic dynein 1 heavy chain 1 OS=Homo sapiens OX=9606 GN=DYNC1H1 PE=1 SV=5 4.18 3119.1 - 870652 - - - -0.2582 - 3.576 0.516 - 515.1 1 2 1 -0.0005 18 0 0 0 1.77E+07 1.44E+07 - - - 7.4657 1 221125_WJC_METTL3_EV_vs_WT_F05.18510.18510.3 3.20E-10 16/76 R.GSMAGSTGVHDTVVNQLLSK[136.11].L "sp|P46459|NSF_HUMAN,tr|I3L0N3|I3L0N3_HUMAN" 2 2008.0139 0.83 69537 18510 3 2008.015492 670.3452 Vesicle-fusing ATPase OS=Homo sapiens OX=9606 GN=NSF PE=1 SV=3 6.74 3119.2 - 757613 - - - 0.7978 - 2.901 0.63 - 269.4 1 2 0 0.0016 20 0 0 0 6.26E+06 7.51E+06 - - - 8.1473 0.9998 221125_WJC_METTL3_EV_vs_WT_F05.18511.18511.3 0.00195 Dec-76 R.GSMAGSTGVHDTVVNQLLSK.L "sp|P46459|NSF_HUMAN,tr|I3L0N3|I3L0N3_HUMAN" 2 1999.9997 0.76 69538 18511 3 1999.996476 667.6738 Vesicle-fusing ATPase OS=Homo sapiens OX=9606 GN=NSF PE=1 SV=3 6.74 3119.3 - 752888 - - - -1.607 - 2.454 0.391 - 126.9 1 2 0 -0.0032 20 0 0 0 6.46E+06 8.46E+06 - - - 5.0763 0.9997 221125_WJC_METTL3_EV_vs_WT_F05.18517.18517.3 0.0574 Oct-60 K.VTSSIPVFDLQDGGRK.L sp|Q7Z3K3|POGZ_HUMAN 1 1717.8999 0.74 69544 18517 3 1717.901321 573.6406 Pogo transposable element with ZNF domain OS=Homo sapiens OX=9606 GN=POGZ PE=1 SV=2 5.93 3120.1 - 264381 - - - 0.8278 - 2.184 0.326 - 120.8 1 2 0 0.0014 16 0 0 0 2.13E+06 2.88E+06 - - - 4.1785 0.8389 221125_WJC_METTL3_EV_vs_WT_F05.18519.18519.3 0.948 Aug-64 K.TPPEDC[160.03]EGPFRPAEILK.E sp|P49790|NU153_HUMAN 1 1954.9459 1.18 69546 18519 3 1954.949675 652.6559 Nuclear pore complex protein Nup153 OS=Homo sapiens OX=9606 GN=NUP153 PE=1 SV=2 4.41 3120.3 - 167974 - - - 1.9499 - 1.21 0.132 - 63.6 1 2 0 0.0038 17 0 0 0 1.31E+06 1.11E+06 - - - 0.4922 0.9934 221125_WJC_METTL3_EV_vs_WT_F05.18520.18520.3 0.366 Aug-44 R.DIKPDNLLLDAK.G "sp|Q9Y2H1|ST38L_HUMAN,tr|F5H277|F5H277_HUMAN,tr|H0YGN4|H0YGN4_HUMAN" 3 1353.7504 3.88 69547 18520 3 1353.752368 452.2574 Serine\threonine-protein kinase 38-like OS=Homo sapiens OX=9606 GN=STK38L PE=1 SV=3 4.43 3120.4 - 165284 - - - 1.4678 - 1.75 0.196 - 111.6 1 2 0 0.002 12 0 0 0 1.79E+06 4.61E+05 - - - 2.2758 1 221125_WJC_METTL3_EV_vs_WT_F05.18526.18526.2 1.88E-08 18/26 R.VPTANVSVVDLTC[160.03]R.L "sp|P04406|G3P_HUMAN,tr|E7EUT5|E7EUT5_HUMAN" 2 1529.7872 4.36 69551 18526 2 1529.789293 765.9009 Glyceraldehyde-3-phosphate dehydrogenase OS=Homo sapiens OX=9606 GN=GAPDH PE=1 SV=3 5.8 3121.3 - 1.34E+06 - - - 1.3825 - 3.527 0.668 - 1162.7 1 2 0 0.0021 14 0 0 0 3.68E+07 8.45E+06 - - - 7.1372 0.9979 221125_WJC_METTL3_EV_vs_WT_F05.18529.18529.4 0.00026 17/102 R.AFLHYPGLVVPQPQRPDK.C sp|P50548|ERF_HUMAN 1 2061.116 1.61 69554 18529 4 2061.123295 516.2863 ETS domain-containing transcription factor ERF OS=Homo sapiens OX=9606 GN=ERF PE=1 SV=2 8.64 3121.6 - 553451 - - - 3.549 - 3.189 0.321 - 141.7 1 2 0 0.0073 18 0 0 0 4.80E+06 2.98E+06 - - - 2.4152 0.9996 221125_WJC_METTL3_EV_vs_WT_F05.18532.18532.4 0.000146 18/84 R.ELDTVTLEDIK[136.11]EHVK[136.11].Q sp|O43242|PSMD3_HUMAN 1 1783.9538 0.62 69557 18532 4 1783.957809 446.9957 26S proteasome non-ATPase regulatory subunit 3 OS=Homo sapiens OX=9606 GN=PSMD3 PE=1 SV=2 4.5 3122 - 396142 - - - 2.222 - 3.021 0.45 - 272.1 1 2 1 0.004 15 0 0 0 5.34E+06 8.54E+06 - - - 3.5373 0.9999 221125_WJC_METTL3_EV_vs_WT_F05.18534.18534.2 3.43E-05 24-Oct K.ENFPNFLSAC[160.03]DKK.G "sp|Q86SG5|S1A7A_HUMAN,sp|P31151|S10A7_HUMAN" 2 1568.7293 999 69559 18534 2 1568.730224 785.3719 Protein S100-A7A OS=Homo sapiens OX=9606 GN=S100A7A PE=1 SV=3 6.16 3122.3 - 347780 - - - 0.5712 - 2.215 0.495 - 283.4 1 2 0 0.0009 13 0 0 0 5.60E+06 0.00E+00 - - - 4.7378 0.9987 221125_WJC_METTL3_EV_vs_WT_F05.18535.18535.3 0.00018 17/72 K.LLELTSSYSPDVSDYK[136.11]EGR[166.11].L sp|P38432|COIL_HUMAN 1 2176.0655 0.85 69560 18535 3 2176.075155 726.3624 Coilin OS=Homo sapiens OX=9606 GN=COIL PE=1 SV=1 4.32 3122.4 - 334925 - - - 4.4535 - 2.923 0.495 - 333.7 1 2 1 0.0097 19 0 0 0 2.45E+06 2.87E+06 - - - 6.6913 0.9957 221125_WJC_METTL3_EV_vs_WT_F05.18536.18536.3 0.0565 Sep-60 K.VTSSIPVFDLQDGGR[166.11]K[136.11].L sp|Q7Z3K3|POGZ_HUMAN 1 1735.9224 0.74 69561 18536 3 1735.926388 579.6481 Pogo transposable element with ZNF domain OS=Homo sapiens OX=9606 GN=POGZ PE=1 SV=2 5.93 3122.5 - 322810 - - - 2.3152 - 1.956 0.237 - 103.7 1 2 0 0.004 16 0 0 0 2.13E+06 2.88E+06 - - - 2.9026 1 221125_WJC_METTL3_EV_vs_WT_F05.18537.18537.2 4.46E-06 16/28 R.NFILDQTNVSAAAQR[166.11].R "sp|Q00839|HNRPU_HUMAN,tr|A0A1W2PQL0|A0A1W2PQL0_HUMAN,tr|A0A1W2PPL4|A0A1W2PPL4_HUMAN,tr|A0A1W2PQ74|A0A1W2PQ74_HUMAN,tr|Q5RI18|Q5RI18_HUMAN,tr|A0A1W2PP35|A0A1W2PP35_HUMAN,tr|A0A1W2PPS1|A0A1W2PPS1_HUMAN,tr|A0A1W2PRZ7|A0A1W2PRZ7_HUMAN,tr|A0A1W2PPH7|A0A1W2PPH7_HUMAN,tr|A0A1W2PQD4|A0A1W2PQD4_HUMAN,tr|A0A1W2PP34|A0A1W2PP34_HUMAN,tr|A0A1X7SBS1|A0A1X7SBS1_HUMAN" 12 1656.8459 1 69562 18537 2 1656.851905 829.4302 Heterogeneous nuclear ribonucleoprotein U OS=Homo sapiens OX=9606 GN=HNRNPU PE=1 SV=6 5.84 3122.7 - 312188 - - - 3.6225 - 3.093 0.578 - 970.1 1 2 0 0.006 15 0 0 0 1.12E+07 1.12E+07 - - - 6.0843 0.9999 221125_WJC_METTL3_EV_vs_WT_F05.18538.18538.3 1.09E-07 13/84 R.VLEDEEGSK[136.11]DIELSDDPYDC[160.03]IR[166.11].L sp|Q15024|EXOS7_HUMAN 1 2614.1711 1.23 69563 18538 3 2614.172474 872.3977 Exosome complex component RRP42 OS=Homo sapiens OX=9606 GN=EXOSC7 PE=1 SV=3 3.76 3122.8 - 261649 - - - 0.5149 - 2.838 0.582 - 129.9 1 2 1 0.0013 22 0 0 0 1.45E+06 1.17E+06 - - - 7.5014 0.9998 221125_WJC_METTL3_EV_vs_WT_F05.18539.18539.3 0.0103 18/56 R.ELDTVTLEDIK[136.11]EHVK[136.11].Q sp|O43242|PSMD3_HUMAN 1 1783.9538 0.39 69564 18539 3 1783.958655 595.6586 26S proteasome non-ATPase regulatory subunit 3 OS=Homo sapiens OX=9606 GN=PSMD3 PE=1 SV=2 4.5 3122.9 - 219142 - - - 2.6963 - 3.703 0.551 - 391 1 2 1 0.0048 15 0 0 0 1.98E+06 5.09E+06 - - - 8.0978 0.9689 221125_WJC_METTL3_EV_vs_WT_F05.18540.18540.4 0.0138 Oct-96 K.EVLAGR[166.11]PLFPHVLC[160.03]HNC[160.03].A "sp|Q00839|HNRPU_HUMAN,tr|A0A1W2PQL0|A0A1W2PQL0_HUMAN,tr|A0A1W2PPL4|A0A1W2PPL4_HUMAN,tr|A0A1W2PQ74|A0A1W2PQ74_HUMAN,tr|Q5RI18|Q5RI18_HUMAN,tr|A0A1W2PP35|A0A1W2PP35_HUMAN,tr|A0A1W2PPS1|A0A1W2PPS1_HUMAN,tr|A0A1W2PRZ7|A0A1W2PRZ7_HUMAN,tr|A0A1W2PPH7|A0A1W2PPH7_HUMAN,tr|A0A1W2PP34|A0A1W2PP34_HUMAN,tr|A0A1X7SBS1|A0A1X7SBS1_HUMAN" 11 2028.0061 1.35 69565 18540 4 2028.006754 508.0088 Heterogeneous nuclear ribonucleoprotein U OS=Homo sapiens OX=9606 GN=HNRNPU PE=1 SV=6 6.99 3123.1 - 196384 - - - 0.3097 - 1.667 0.374 - 61.1 1 1 0 0.0006 17 0 0 0 1.31E+06 9.71E+05 - - - 2.6585 1 221125_WJC_METTL3_EV_vs_WT_F05.18543.18543.3 1.68E-06 13/48 K.K[136.11]NAAIAVLEELK[136.11]K[136.11].L "sp|O95793|STAU1_HUMAN,tr|Q5JW30|Q5JW30_HUMAN,tr|Q5JW28|Q5JW28_HUMAN" 3 1449.8981 2.36 69568 18543 3 1449.901916 484.3066 Double-stranded RNA-binding protein Staufen homolog 1 OS=Homo sapiens OX=9606 GN=STAU1 PE=1 SV=2 8.5 3123.4 - 165003 - - - 2.6216 - 2.819 0.541 - 249.9 1 2 0 0.0038 13 0 0 0 3.42E+06 1.45E+06 - - - 7.3805 1 221125_WJC_METTL3_EV_vs_WT_F05.18548.18548.2 1.75E-10 17/28 R.NFILDQTNVSAAAQR.R "sp|Q00839|HNRPU_HUMAN,tr|A0A1W2PQL0|A0A1W2PQL0_HUMAN,tr|A0A1W2PPL4|A0A1W2PPL4_HUMAN,tr|A0A1W2PQ74|A0A1W2PQ74_HUMAN,tr|Q5RI18|Q5RI18_HUMAN,tr|A0A1W2PP35|A0A1W2PP35_HUMAN,tr|A0A1W2PPS1|A0A1W2PPS1_HUMAN,tr|A0A1W2PRZ7|A0A1W2PRZ7_HUMAN,tr|A0A1W2PPH7|A0A1W2PPH7_HUMAN,tr|A0A1W2PQD4|A0A1W2PQD4_HUMAN,tr|A0A1W2PP34|A0A1W2PP34_HUMAN,tr|A0A1X7SBS1|A0A1X7SBS1_HUMAN" 12 1646.8376 1 69572 18548 2 1646.841467 824.4261 Heterogeneous nuclear ribonucleoprotein U OS=Homo sapiens OX=9606 GN=HNRNPU PE=1 SV=6 5.84 3124.1 - 899940 - - - 2.3281 - 3.336 0.593 - 1093.6 1 2 0 0.0038 15 0 0 0 1.12E+07 1.12E+07 - - - 6.3817 1 221125_WJC_METTL3_EV_vs_WT_F05.18549.18549.3 2.29E-08 20/64 R.NLSDVATKQEGLESVLK.L sp|P14923|PLAK_HUMAN 1 1829.9735 20.05 69573 18549 3 1829.979641 610.9984 Junction plakoglobin OS=Homo sapiens OX=9606 GN=JUP PE=1 SV=3 4.68 3124.2 - 874681 - - - 3.3787 - 3.626 0.614 - 380.2 1 2 1 0.0062 17 0 0 0 3.31E+06 1.65E+05 - - - 8.638 0.9997 221125_WJC_METTL3_EV_vs_WT_F05.18550.18550.3 1.22E-06 15/56 R.NFILDQTNVSAAAQR.R "sp|Q00839|HNRPU_HUMAN,tr|A0A1W2PQL0|A0A1W2PQL0_HUMAN,tr|A0A1W2PPL4|A0A1W2PPL4_HUMAN,tr|A0A1W2PQ74|A0A1W2PQ74_HUMAN,tr|Q5RI18|Q5RI18_HUMAN,tr|A0A1W2PP35|A0A1W2PP35_HUMAN,tr|A0A1W2PPS1|A0A1W2PPS1_HUMAN,tr|A0A1W2PRZ7|A0A1W2PRZ7_HUMAN,tr|A0A1W2PPH7|A0A1W2PPH7_HUMAN,tr|A0A1W2PQD4|A0A1W2PQD4_HUMAN,tr|A0A1W2PP34|A0A1W2PP34_HUMAN,tr|A0A1X7SBS1|A0A1X7SBS1_HUMAN" 12 1646.8376 0.99 69574 18550 3 1646.844528 549.9532 Heterogeneous nuclear ribonucleoprotein U OS=Homo sapiens OX=9606 GN=HNRNPU PE=1 SV=6 5.84 3124.3 - 867254 - - - 4.1868 - 2.831 0.479 - 280.7 1 2 0 0.0069 15 0 0 0 9.32E+06 9.45E+06 - - - 6.5939 0.9996 221125_WJC_METTL3_EV_vs_WT_F05.18553.18553.4 0.00168 14/84 R.ELDTVTLEDIKEHVK.Q sp|O43242|PSMD3_HUMAN 1 1767.9254 0.62 69577 18553 4 1767.928504 442.9886 26S proteasome non-ATPase regulatory subunit 3 OS=Homo sapiens OX=9606 GN=PSMD3 PE=1 SV=2 4.5 3124.7 - 491354 - - - 1.7303 - 2.852 0.436 - 134 1 2 1 0.0031 15 0 0 0 5.34E+06 8.54E+06 - - - 3.3951 1 221125_WJC_METTL3_EV_vs_WT_F05.18554.18554.4 2.88E-08 16/78 R.GGFC[160.03]NFMHLK[136.11]PISR[166.11].E sp|Q01081|U2AF1_HUMAN 1 1680.8348 0.88 69578 18554 4 1680.839191 421.216 Splicing factor U2AF 35 kDa subunit OS=Homo sapiens OX=9606 GN=U2AF1 PE=1 SV=3 9.51 3124.8 - 379413 - - - 2.638 - 2.959 0.593 - 154.8 1 2 0 0.0044 14 0 0 0 2.61E+06 2.98E+06 - - - 4.7811 1 221125_WJC_METTL3_EV_vs_WT_F05.18556.18556.4 7.51E-09 16/78 R.GGFC[160.03]NFMHLKPISR.E sp|Q01081|U2AF1_HUMAN 1 1662.8123 0.88 69580 18556 4 1662.81627 416.7103 Splicing factor U2AF 35 kDa subunit OS=Homo sapiens OX=9606 GN=U2AF1 PE=1 SV=3 9.51 3125.1 - 345549 - - - 2.3953 - 2.965 0.625 - 151.5 1 2 0 0.004 14 0 0 0 2.61E+06 2.98E+06 - - - 5.0605 0.9786 221125_WJC_METTL3_EV_vs_WT_F05.18557.18557.3 2.02E-07 13/60 K.EVLAGRPLFPHVLC[160.03]HN.C "sp|Q00839|HNRPU_HUMAN,tr|A0A1W2PQL0|A0A1W2PQL0_HUMAN,tr|A0A1W2PPL4|A0A1W2PPL4_HUMAN,tr|A0A1W2PQ74|A0A1W2PQ74_HUMAN,tr|Q5RI18|Q5RI18_HUMAN,tr|A0A1W2PP35|A0A1W2PP35_HUMAN,tr|A0A1W2PPS1|A0A1W2PPS1_HUMAN,tr|A0A1W2PRZ7|A0A1W2PRZ7_HUMAN,tr|A0A1W2PPH7|A0A1W2PPH7_HUMAN,tr|A0A1W2PP34|A0A1W2PP34_HUMAN,tr|A0A1X7SBS1|A0A1X7SBS1_HUMAN" 11 1857.9672 7.16 69581 18557 3 1857.974321 620.3297 Heterogeneous nuclear ribonucleoprotein U OS=Homo sapiens OX=9606 GN=HNRNPU PE=1 SV=6 7 3125.2 - 340022 - - - 3.8284 - 2.605 0.496 - 125.8 1 1 0 0.0071 16 0 0 0 2.65E+06 3.71E+05 - - - 6.5246 1 221125_WJC_METTL3_EV_vs_WT_F05.18558.18558.3 5.18E-14 18/68 K.DMSGHYQNALYLGDVSER[166.11].V "sp|P53621|COPA_HUMAN,tr|A0A3B3ISC6|A0A3B3ISC6_HUMAN,tr|A0A3B3IS84|A0A3B3IS84_HUMAN,tr|A0A3B3IU89|A0A3B3IU89_HUMAN,tr|A0A3B3IT15|A0A3B3IT15_HUMAN" 5 2063.9246 0.2 69582 18558 3 2063.928913 688.9822 Coatomer subunit alpha OS=Homo sapiens OX=9606 GN=COPA PE=1 SV=2 4.54 3125.3 - 285454 - - - 2.0781 - 3.423 0.679 - 427.5 1 2 0 0.0043 18 0 0 0 5.30E+05 2.69E+06 - - - 9.1731 1 221125_WJC_METTL3_EV_vs_WT_F05.18559.18559.3 4.37E-10 Nov-84 R.VLEDEEGSKDIELSDDPYDC[160.03]IR.L sp|Q15024|EXOS7_HUMAN 1 2596.1487 1.23 69583 18559 3 2596.152085 866.3902 Exosome complex component RRP42 OS=Homo sapiens OX=9606 GN=EXOSC7 PE=1 SV=3 3.76 3125.4 - 277366 - - - 1.32 - 2.706 0.698 - 70 1 2 1 0.0034 22 0 0 0 1.45E+06 1.17E+06 - - - 8.6812 0.9997 221125_WJC_METTL3_EV_vs_WT_F05.18562.18562.3 2.05E-05 Nov-88 R.QEPYYPQQYGHYGYNQRPPYGYY.- "sp|Q9BTL3|RAMAC_HUMAN,tr|A0A3B3IU46|A0A3B3IU46_HUMAN" 2 2930.2725 1.55 69586 18562 3 2930.277012 977.7648 RNA guanine-N7 methyltransferase activating subunit OS=Homo sapiens OX=9606 GN=RAMAC PE=1 SV=1 6.74 3125.8 - 184833 - - - 1.5418 - 2.032 0.38 - 94 1 2 0 0.0045 23 0 0 0 1.22E+06 7.91E+05 - - - 4.4387 0.9999 221125_WJC_METTL3_EV_vs_WT_F05.18565.18565.3 7.47E-05 Aug-88 R.QEPYYPQQYGHYGYNQR[166.11]PPYGYY.- "sp|Q9BTL3|RAMAC_HUMAN,tr|A0A3B3IU46|A0A3B3IU46_HUMAN" 2 2940.2808 1.55 69589 18565 3 2940.280977 981.1009 RNA guanine-N7 methyltransferase activating subunit OS=Homo sapiens OX=9606 GN=RAMAC PE=1 SV=1 6.74 3126.2 - 132582 - - - 0.0724 - 1.929 0.439 - 44.9 1 2 0 0.0002 23 0 0 0 1.22E+06 7.91E+05 - - - 4.9756 0.9993 221125_WJC_METTL3_EV_vs_WT_F05.18574.18574.3 0.00038 15/68 R.AERDPEFAPPSDYFVGQK.R "sp|Q6PII3|CC174_HUMAN,tr|A0A0B4J1R8|A0A0B4J1R8_HUMAN,tr|A0A087WYA9|A0A087WYA9_HUMAN" 3 2051.9589 1.8 69597 18574 3 2051.963348 684.9936 Coiled-coil domain-containing protein 174 OS=Homo sapiens OX=9606 GN=CCDC174 PE=1 SV=3 4.32 3127.3 - 201862 - - - 2.1818 - 2.331 0.442 - 211.8 1 2 1 0.0045 18 0 0 0 1.24E+06 6.88E+05 - - - 5.574 0.9984 221125_WJC_METTL3_EV_vs_WT_F05.18575.18575.3 0.000379 Sep-68 K.TAESQTPTPSATSFFSGK[136.11].S "sp|P55265|DSRAD_HUMAN,tr|A0A3B3ITG9|A0A3B3ITG9_HUMAN,tr|A0A3B3IRQ9|A0A3B3IRQ9_HUMAN,tr|A0A3B3ISU1|A0A3B3ISU1_HUMAN,tr|A0A7P0Z4K3|A0A7P0Z4K3_HUMAN,tr|A0A3B3ISX1|A0A3B3ISX1_HUMAN,tr|A0A7P0Z4F9|A0A7P0Z4F9_HUMAN" 7 1850.8778 14.87 69598 18575 3 1850.885343 617.9665 Double-stranded RNA-specific adenosine deaminase OS=Homo sapiens OX=9606 GN=ADAR PE=1 SV=4 5.66 3127.4 - 182482 - - - 4.09 - 1.925 0.401 - 80.5 1 2 0 0.0076 18 0 0 0 2.02E+07 1.36E+06 - - - 4.6395 0.9969 221125_WJC_METTL3_EV_vs_WT_F05.18576.18576.3 0.0461 Jul-52 R.VPTANVSVVDLTC[160.03]R.L "sp|P04406|G3P_HUMAN,tr|E7EUT5|E7EUT5_HUMAN" 2 1529.7872 0.56 69599 18576 3 1529.788333 510.9363 Glyceraldehyde-3-phosphate dehydrogenase OS=Homo sapiens OX=9606 GN=GAPDH PE=1 SV=3 5.8 3127.6 - 173608 - - - 0.755 - 1.499 0.263 - 36.6 1 2 0 0.0012 14 0 0 0 4.05E+06 7.24E+06 - - - 2.5476 1 221125_WJC_METTL3_EV_vs_WT_F05.18582.18582.2 2.41E-11 13/34 K.TAESQTPTPSATSFFSGK.S "sp|P55265|DSRAD_HUMAN,tr|A0A3B3ITG9|A0A3B3ITG9_HUMAN,tr|A0A3B3IRQ9|A0A3B3IRQ9_HUMAN,tr|A0A3B3ISU1|A0A3B3ISU1_HUMAN,tr|A0A7P0Z4K3|A0A7P0Z4K3_HUMAN,tr|A0A3B3ISX1|A0A3B3ISX1_HUMAN,tr|A0A7P0Z4F9|A0A7P0Z4F9_HUMAN" 7 1842.8636 -1 69605 18582 2 1842.869006 922.4391 Double-stranded RNA-specific adenosine deaminase OS=Homo sapiens OX=9606 GN=ADAR PE=1 SV=4 5.66 3128.4 - 111106 - - - 2.9481 - 3.039 0.678 - 401.6 1 2 0 0.0054 18 0 0 0 0.00E+00 0.00E+00 - - - 6.7797 1 221125_WJC_METTL3_EV_vs_WT_F05.18583.18583.2 5.82E-09 Oct-34 K.TAESQTPTPSATSFFSGK[136.11].S "sp|P55265|DSRAD_HUMAN,tr|A0A3B3ITG9|A0A3B3ITG9_HUMAN,tr|A0A3B3IRQ9|A0A3B3IRQ9_HUMAN,tr|A0A3B3ISU1|A0A3B3ISU1_HUMAN,tr|A0A7P0Z4K3|A0A7P0Z4K3_HUMAN,tr|A0A3B3ISX1|A0A3B3ISX1_HUMAN,tr|A0A7P0Z4F9|A0A7P0Z4F9_HUMAN" 7 1850.8778 0.62 69606 18583 2 1850.876906 926.4462 Double-stranded RNA-specific adenosine deaminase OS=Homo sapiens OX=9606 GN=ADAR PE=1 SV=4 5.66 3128.5 - 88237.1 - - - -0.4684 - 2.461 0.633 - 214.8 1 2 0 -0.0009 18 0 0 0 5.93E+05 9.60E+05 - - - 5.9302 0.9994 221125_WJC_METTL3_EV_vs_WT_F05.18592.18592.3 2.78E-05 15/48 K.ER[166.11]EIAQLVEDVQR[166.11].L "sp|Q13948|CASP_HUMAN,sp|P39880|CUX1_HUMAN,tr|A0A2R8Y852|A0A2R8Y852_HUMAN,tr|A0A2R8YDI1|A0A2R8YDI1_HUMAN" 4 1603.8433 1.86 69613 18592 3 1603.849026 535.6217 Protein CASP OS=Homo sapiens OX=9606 GN=CUX1 PE=1 SV=2 4.41 3129.5 - 654428 - - - 3.5864 - 2.68 0.508 - 414.3 1 2 1 0.0058 13 0 0 0 9.02E+06 4.84E+06 - - - 6.8749 1 221125_WJC_METTL3_EV_vs_WT_F05.18595.18595.3 4.03E-12 20/72 K.LHGLNINYNC[160.03]EIC[160.03]GNYTYR.G sp|Q12874|SF3A3_HUMAN 1 2373.063 3.69 69616 18595 3 2373.06759 792.0283 Splicing factor 3A subunit 3 OS=Homo sapiens OX=9606 GN=SF3A3 PE=1 SV=1 6.73 3129.9 - 341444 - - - 1.9195 - 3.607 0.699 - 521.4 1 2 0 0.0046 19 0 0 0 2.61E+06 7.06E+05 - - - 9.4837 0.8506 221125_WJC_METTL3_EV_vs_WT_F05.18596.18596.4 0.0633 Nov-96 R.IIDKNGIHDLDNISFPK.Q "sp|P49721|PSB2_HUMAN,tr|A0A087WVV1|A0A087WVV1_HUMAN" 2 1938.0211 0.57 69617 18596 4 1938.028136 485.5125 Proteasome subunit beta type-2 OS=Homo sapiens OX=9606 GN=PSMB2 PE=1 SV=1 5.3 3130 - 306532 - - - 3.6424 - 1.595 0.21 - 81.1 1 2 1 0.0071 17 0 0 0 1.52E+06 2.64E+06 - - - 1.214 0.9997 221125_WJC_METTL3_EV_vs_WT_F05.18597.18597.3 0.000128 Nov-52 K.DLANLEVPHELPTK.Q "sp|Q8WXI9|P66B_HUMAN,tr|A0A0U1RR34|A0A0U1RR34_HUMAN,tr|A0A0U1RRM1|A0A0U1RRM1_HUMAN,tr|A0A0U1RRK3|A0A0U1RRK3_HUMAN" 4 1574.8304 108.94 69618 18597 3 1574.8348 525.9508 Transcriptional repressor p66-beta OS=Homo sapiens OX=9606 GN=GATAD2B PE=1 SV=1 4.65 3130.1 - 277536 - - - 2.78 - 2.212 0.416 - 101.7 1 2 0 0.0044 14 0 0 0 3.38E+06 3.10E+04 - - - 5.2866 0.7864 221125_WJC_METTL3_EV_vs_WT_F05.18598.18598.4 0.0135 Oct-96 K.EVLAGRPLFPHVLC[160.03]HNC[160.03].A "sp|Q00839|HNRPU_HUMAN,tr|A0A1W2PQL0|A0A1W2PQL0_HUMAN,tr|A0A1W2PPL4|A0A1W2PPL4_HUMAN,tr|A0A1W2PQ74|A0A1W2PQ74_HUMAN,tr|Q5RI18|Q5RI18_HUMAN,tr|A0A1W2PP35|A0A1W2PP35_HUMAN,tr|A0A1W2PPS1|A0A1W2PPS1_HUMAN,tr|A0A1W2PRZ7|A0A1W2PRZ7_HUMAN,tr|A0A1W2PPH7|A0A1W2PPH7_HUMAN,tr|A0A1W2PP34|A0A1W2PP34_HUMAN,tr|A0A1X7SBS1|A0A1X7SBS1_HUMAN" 11 2017.9979 0.81 69619 18598 4 2018.005392 505.5067 Heterogeneous nuclear ribonucleoprotein U OS=Homo sapiens OX=9606 GN=HNRNPU PE=1 SV=6 6.99 3130.3 - 220289 - - - 3.7344 - 1.529 0.352 - 42 1 1 0 0.0075 17 0 0 0 1.06E+06 1.30E+06 - - - 2.4351 1 221125_WJC_METTL3_EV_vs_WT_F05.18602.18602.3 7.57E-11 17/120 Y.GAQSAAAATGSYGAAAAYGAQPSATLAAPYR.T sp|Q96PK6|RBM14_HUMAN 1 2841.3682 7.85 69623 18602 3 2841.370226 948.13 RNA-binding protein 14 OS=Homo sapiens OX=9606 GN=RBM14 PE=1 SV=2 8.5 3130.8 - 186278 - - - 0.7183 - 3.457 0.71 - 123.3 1 1 0 0.002 31 0 0 0 1.51E+06 1.93E+05 - - - 9.3089 0.9984 221125_WJC_METTL3_EV_vs_WT_F05.18603.18603.3 1.93E-05 Sep-84 R.EMGSATSVAGVVNGESLEDIR[166.11]K[136.11].N sp|P54198|HIRA_HUMAN 1 2266.123 1.32 69624 18603 3 2266.129384 756.3816 Protein HIRA OS=Homo sapiens OX=9606 GN=HIRA PE=1 SV=2 4.41 3130.9 - 135734 - - - 2.8189 - 1.718 0.364 - 39.1 1 2 0 0.0064 22 0 0 0 9.30E+05 7.06E+05 - - - 3.8795 0.9951 221125_WJC_METTL3_EV_vs_WT_F05.18606.18606.3 0.00659 23/76 M.RILSAENIPNLPPGGGLAGK.R "sp|O75688|PPM1B_HUMAN,tr|B8ZZF0|B8ZZF0_HUMAN,tr|A0A3B3IS24|A0A3B3IS24_HUMAN,tr|C9JIR6|C9JIR6_HUMAN" 4 1973.1058 -1 69626 18606 3 1973.112447 658.7092 Protein phosphatase 1B OS=Homo sapiens OX=9606 GN=PPM1B PE=1 SV=1 8.75 3131.3 - 2.16E+06 - - - 3.3637 - 3.716 0.602 - 493.8 1 1 0 0.0066 20 0 0 0 0.00E+00 0.00E+00 - - - 8.4344 0.9997 221125_WJC_METTL3_EV_vs_WT_F05.18607.18607.4 1.01E-05 23/132 R.IVSR[166.11]PEELR[166.11]EDDVGTGAGLLEIK[136.11].K "sp|P49368|TCPG_HUMAN,tr|B4DUR8|B4DUR8_HUMAN" 2 2523.3539 0.26 69627 18607 4 2523.361 631.8457 T-complex protein 1 subunit gamma OS=Homo sapiens OX=9606 GN=CCT3 PE=1 SV=4 4.36 3131.4 - 3.25E+06 - - - 2.8248 - 3.012 0.529 - 249.6 1 2 1 0.0071 23 0 0 0 1.72E+08 6.67E+08 - - - 4.1857 1 221125_WJC_METTL3_EV_vs_WT_F05.18609.18609.3 2.00E-11 20/68 R.ELGIC[160.03]PDDAAVIPIKNNR.F sp|P12273|PIP_HUMAN 1 1994.0255 430.25 69629 18609 3 1994.032075 665.6824 Prolactin-inducible protein OS=Homo sapiens OX=9606 GN=PIP PE=1 SV=1 4.56 3131.5 - 783595 - - - 3.2918 - 3.35 0.644 - 410.2 1 2 1 0.0066 18 0 0 0 8.10E+07 1.88E+05 - - - 8.7286 0.9998 221125_WJC_METTL3_EV_vs_WT_F05.18610.18610.3 8.32E-09 19/76 K.VDKIEELDQENEAALENGIK.N "sp|P43243|MATR3_HUMAN,tr|B3KM87|B3KM87_HUMAN,tr|A8MXP9|A8MXP9_HUMAN,tr|A0A0R4J2E8|A0A0R4J2E8_HUMAN,tr|D6REM6|D6REM6_HUMAN" 5 2256.1121 2.74 69630 18610 3 2256.11946 753.0447 Matrin-3 OS=Homo sapiens OX=9606 GN=MATR3 PE=1 SV=2 4 3131.7 - 753399 - - - 3.2463 - 3.717 0.583 - 426.7 1 2 1 0.0073 20 0 0 0 7.99E+07 2.91E+07 - - - 8.223 1 221125_WJC_METTL3_EV_vs_WT_F05.18612.18612.3 0.000971 14/64 K.FVINYDYPNSSEDYVHR.L "sp|Q92841|DDX17_HUMAN,tr|A0A5H1ZRQ2|A0A5H1ZRQ2_HUMAN,tr|A0A1X7SBZ2|A0A1X7SBZ2_HUMAN" 3 2116.949 0.93 69632 18612 3 2116.952341 706.657 Probable ATP-dependent RNA helicase DDX17 OS=Homo sapiens OX=9606 GN=DDX17 PE=1 SV=2 4.54 3131.9 - 569012 - - - 1.5622 - 2.925 0.571 - 210.5 1 2 0 0.0033 17 0 0 0 2.76E+06 2.97E+06 - - - 7.6166 1 221125_WJC_METTL3_EV_vs_WT_F05.18613.18613.3 7.77E-09 Dec-68 R.SADEPMTTFVVC[160.03]NEC[160.03]GNR.W "sp|P23193|TCEA1_HUMAN,tr|B7Z4S1|B7Z4S1_HUMAN,tr|A0A1W2PRL9|A0A1W2PRL9_HUMAN,tr|A0A1W2PPZ5|A0A1W2PPZ5_HUMAN" 4 2085.8554 1.18 69633 18613 3 2085.862155 696.2924 Transcription elongation factor A protein 1 OS=Homo sapiens OX=9606 GN=TCEA1 PE=1 SV=2 4.14 3132.1 - 461515 - - - 3.2337 - 3.078 0.703 - 187.5 1 2 0 0.0067 18 0 0 0 2.62E+06 2.23E+06 - - - 9.1755 0.9999 221125_WJC_METTL3_EV_vs_WT_F05.18616.18616.3 1.10E-09 16/68 R.SADEPMTTFVVC[160.03]NEC[160.03]GNR[166.11].W "sp|P23193|TCEA1_HUMAN,tr|B7Z4S1|B7Z4S1_HUMAN,tr|A0A1W2PRL9|A0A1W2PRL9_HUMAN,tr|A0A1W2PPZ5|A0A1W2PPZ5_HUMAN" 4 2095.8637 1.18 69636 18616 3 2095.870526 699.6285 Transcription elongation factor A protein 1 OS=Homo sapiens OX=9606 GN=TCEA1 PE=1 SV=2 4.14 3132.5 - 425746 - - - 3.2664 - 3.223 0.53 - 350.1 1 2 0 0.0068 18 0 0 0 2.62E+06 2.23E+06 - - - 7.3613 1 221125_WJC_METTL3_EV_vs_WT_F05.18620.18620.2 5.32E-13 15/34 R.SADEPMTTFVVC[160.03]NEC[160.03]GNR.W "sp|P23193|TCEA1_HUMAN,tr|B7Z4S1|B7Z4S1_HUMAN,tr|A0A1W2PRL9|A0A1W2PRL9_HUMAN,tr|A0A1W2PPZ5|A0A1W2PPZ5_HUMAN" 4 2085.8554 0.93 69640 18620 2 2085.859745 1043.935 Transcription elongation factor A protein 1 OS=Homo sapiens OX=9606 GN=TCEA1 PE=1 SV=2 4.14 3133 - 161874 - - - 2.0783 - 3.443 0.767 - 778.7 1 2 0 0.0043 18 0 0 0 7.20E+05 7.73E+05 - - - 7.7443 1 221125_WJC_METTL3_EV_vs_WT_F05.18623.18623.2 5.28E-07 Sep-36 R.AQTLPTSVVTITSESSPGK[136.11].R "sp|Q01082|SPTB2_HUMAN,tr|A0A087WUZ3|A0A087WUZ3_HUMAN" 2 1910.0088 1.64 69643 18623 2 1910.009823 956.0117 "Spectrin beta chain, non-erythrocytic 1 OS=Homo sapiens OX=9606 GN=SPTBN1 PE=1 SV=2" 6.05 3133.4 - 128141 - - - 0.5424 - 2.476 0.637 - 177.8 1 2 0 0.001 19 0 0 0 6.67E+05 4.06E+05 - - - 5.9746 0.9993 221125_WJC_METTL3_EV_vs_WT_F05.18628.18628.4 2.14E-05 23/132 R.IVSRPEELREDDVGTGAGLLEIK.K "sp|P49368|TCPG_HUMAN,tr|B4DUR8|B4DUR8_HUMAN" 2 2495.3231 0.26 69647 18628 4 2495.332668 624.8381 T-complex protein 1 subunit gamma OS=Homo sapiens OX=9606 GN=CCT3 PE=1 SV=4 4.36 3133.9 - 2.74E+06 - - - 3.8215 - 3.24 0.506 - 299.3 1 2 1 0.0095 23 0 0 0 1.72E+08 6.68E+08 - - - 4.0085 0.9999 221125_WJC_METTL3_EV_vs_WT_F05.18629.18629.3 1.21E-06 27/88 R.IVSR[166.11]PEELR[166.11]EDDVGTGAGLLEIK[136.11].K "sp|P49368|TCPG_HUMAN,tr|B4DUR8|B4DUR8_HUMAN" 2 2523.3539 0.26 69648 18629 3 2523.356983 842.1252 T-complex protein 1 subunit gamma OS=Homo sapiens OX=9606 GN=CCT3 PE=1 SV=4 4.36 3134 - 1.83E+06 - - - 1.2329 - 3.823 0.555 - 486.9 1 2 1 0.0031 23 0 0 0 2.80E+07 1.09E+08 - - - 7.8728 0.9999 221125_WJC_METTL3_EV_vs_WT_F05.18631.18631.4 5.79E-08 13/84 R.GFC[160.03]FITFK[136.11]EEEPVK[136.11]K[136.11].L "sp|Q14103|HNRPD_HUMAN,tr|H0Y8G5|H0Y8G5_HUMAN,tr|H0YA96|H0YA96_HUMAN" 3 1881.9761 1.18 69650 18631 4 1881.980347 471.5013 Heterogeneous nuclear ribonucleoprotein D0 OS=Homo sapiens OX=9606 GN=HNRNPD PE=1 SV=1 6.22 3134.2 - 1.12E+06 - - - 2.2524 - 2.587 0.576 - 93.9 1 2 1 0.0042 15 0 0 0 9.07E+07 7.72E+07 - - - 4.5784 0.9994 221125_WJC_METTL3_EV_vs_WT_F05.18632.18632.2 3.43E-05 22-Nov R.GSTDNLMDDIER[166.11].A sp|P50990|TCPQ_HUMAN 1 1374.5961 0.36 69651 18632 2 1374.600764 688.3053 T-complex protein 1 subunit theta OS=Homo sapiens OX=9606 GN=CCT8 PE=1 SV=4 3.84 3134.4 - 660007 - - - 3.4083 - 2.477 0.515 - 353.7 1 2 0 0.0047 12 0 0 0 1.64E+06 4.55E+06 - - - 5.2299 1 221125_WJC_METTL3_EV_vs_WT_F05.18633.18633.3 2.93E-07 16/60 R.R[166.11]APEEELPPLDPEEIR[166.11].K "sp|Q8IY67|RAVR1_HUMAN,tr|K7EKR9|K7EKR9_HUMAN,tr|E9PAU2|E9PAU2_HUMAN,tr|A0A087WZ13|A0A087WZ13_HUMAN" 4 1908.9696 1.05 69652 18633 3 1908.971251 637.3305 Ribonucleoprotein PTB-binding 1 OS=Homo sapiens OX=9606 GN=RAVER1 PE=1 SV=1 4.14 3134.5 - 646021 - - - 0.8664 - 3.017 0.461 - 333.5 1 2 0 0.0017 16 0 0 0 1.07E+07 1.02E+07 - - - 6.5126 0.9998 221125_WJC_METTL3_EV_vs_WT_F05.18636.18636.3 3.86E-05 Dec-48 K.KDEDIPLFPVQTK.Y "sp|Q9GZR7|DDX24_HUMAN,tr|A0A087WXU8|A0A087WXU8_HUMAN,tr|A0A1W2PRR2|A0A1W2PRR2_HUMAN,tr|F5GYL3|F5GYL3_HUMAN,tr|G3V529|G3V529_HUMAN" 5 1528.8137 1.3 69655 18636 3 1528.818611 510.6118 ATP-dependent RNA helicase DDX24 OS=Homo sapiens OX=9606 GN=DDX24 PE=1 SV=1 4.56 3134.8 - 328869 - - - 3.2058 - 2.083 0.497 - 167.8 1 2 0 0.0049 13 0 0 0 2.87E+06 2.22E+06 - - - 6.0693 0.9998 221125_WJC_METTL3_EV_vs_WT_F05.18637.18637.4 0.000103 14/84 R.VREEVPLELVEAHVK.K sp|Q92922|SMRC1_HUMAN 1 1745.9676 2.81 69656 18637 4 1745.969814 437.4992 SWI\SNF complex subunit SMARCC1 OS=Homo sapiens OX=9606 GN=SMARCC1 PE=1 SV=3 4.91 3134.9 - 234622 - - - 1.2767 - 2.583 0.481 - 146.1 1 2 1 0.0022 15 0 0 0 6.10E+07 2.17E+07 - - - 3.7516 0.9999 221125_WJC_METTL3_EV_vs_WT_F05.18638.18638.3 0.000151 Aug-96 R.LPNGLGGPNGFPKPTPEEGPPELNR.Q sp|Q9H1B7|I2BPL_HUMAN 1 2583.3082 6.26 69657 18638 3 2583.309486 862.11 Probable E3 ubiquitin-protein ligase IRF2BPL OS=Homo sapiens OX=9606 GN=IRF2BPL PE=1 SV=1 4.79 3135.1 - 220873 - - - 0.5168 - 2.215 0.487 - 47.1 1 2 0 0.0013 25 0 0 0 2.75E+06 4.39E+05 - - - 5.7988 0.982 221125_WJC_METTL3_EV_vs_WT_F05.18639.18639.3 6.63E-06 Dec-80 R.QQPPLAQPSASPYPEAVELQR.R "sp|Q9H6R0|DHX33_HUMAN,tr|Q05BE5|Q05BE5_HUMAN,tr|I3L0M5|I3L0M5_HUMAN" 3 2305.1703 1.24 69658 18639 3 2305.159195 769.3974 ATP-dependent RNA helicase DHX33 OS=Homo sapiens OX=9606 GN=DHX33 PE=1 SV=2 4.53 3135.2 - 218824 - - - -4.8001 - 2.5 0.214 - 95.2 1 2 0 -0.0111 21 0 0 0 4.34E+06 3.49E+06 - - - 3.1196 1 221125_WJC_METTL3_EV_vs_WT_F05.18640.18640.2 3.19E-08 28-Dec K.DFETLYNDC[160.03]TNASSR.P sp|Q9UI36|DACH1_HUMAN 1 1791.737 2.82 69659 18640 2 1791.736979 896.8758 Dachshund homolog 1 OS=Homo sapiens OX=9606 GN=DACH1 PE=1 SV=4 4.03 3135.4 - 188236 - - - -0.0078 - 2.693 0.69 - 431 1 1 0 0 15 0 0 0 4.09E+06 1.45E+06 - - - 6.5729 0.9996 221125_WJC_METTL3_EV_vs_WT_F05.18641.18641.3 0.000251 Oct-52 K.HWPFMVVNDAGR[166.11]PK[136.11].V "sp|P11142|HSP7C_HUMAN,tr|E9PQQ4|E9PQQ4_HUMAN,tr|E9PNE6|E9PNE6_HUMAN,tr|E9PKE3|E9PKE3_HUMAN,tr|E9PN89|E9PN89_HUMAN,tr|E9PLF4|E9PLF4_HUMAN,tr|E9PK54|E9PK54_HUMAN,tr|E9PN25|E9PN25_HUMAN,tr|E9PPY6|E9PPY6_HUMAN,tr|E9PQK7|E9PQK7_HUMAN" 10 1670.847 0.33 69660 18641 3 1670.852281 557.9563 Heat shock cognate 71 kDa protein OS=Homo sapiens OX=9606 GN=HSPA8 PE=1 SV=1 8.75 3135.5 - 167713 - - - 3.1391 - 2.004 0.429 - 179.9 1 2 0 0.0052 14 0 0 0 9.21E+05 2.75E+06 - - - 5.1688 1 221125_WJC_METTL3_EV_vs_WT_F05.18642.18642.2 9.12E-09 Aug-34 R.SADEPMTTFVVC[160.03]NEC[160.03]GNR[166.11].W "sp|P23193|TCEA1_HUMAN,tr|B7Z4S1|B7Z4S1_HUMAN,tr|A0A1W2PRL9|A0A1W2PRL9_HUMAN,tr|A0A1W2PPZ5|A0A1W2PPZ5_HUMAN" 4 2095.8637 0.93 69661 18642 2 2095.86719 1048.9391 Transcription elongation factor A protein 1 OS=Homo sapiens OX=9606 GN=TCEA1 PE=1 SV=2 4.14 3135.6 - 155859 - - - 1.6747 - 2.136 0.726 - 181.5 1 2 0 0.0035 18 0 0 0 7.20E+05 7.73E+05 - - - 6.268 1 221125_WJC_METTL3_EV_vs_WT_F05.18643.18643.2 9.34E-11 14/28 K.DFETLYNDC[160.03]TNASSR[166.11].P sp|Q9UI36|DACH1_HUMAN 1 1801.7453 2.82 69662 18643 2 1801.744353 901.8799 Dachshund homolog 1 OS=Homo sapiens OX=9606 GN=DACH1 PE=1 SV=4 4.03 3135.7 - 79969.4 - - - -0.5051 - 2.851 0.774 - 718.9 1 1 0 -0.0009 15 0 0 0 4.09E+06 1.45E+06 - - - 7.3332 1 221125_WJC_METTL3_EV_vs_WT_F05.18647.18647.3 2.21E-06 29/88 R.IVSRPEELREDDVGTGAGLLEIK.K "sp|P49368|TCPG_HUMAN,tr|B4DUR8|B4DUR8_HUMAN" 2 2495.3231 0.26 69664 18647 3 2495.327584 832.7817 T-complex protein 1 subunit gamma OS=Homo sapiens OX=9606 GN=CCT3 PE=1 SV=4 4.36 3136.3 - 782565 - - - 1.7841 - 3.742 0.646 - 603.4 1 2 1 0.0045 23 0 0 0 2.80E+07 1.09E+08 - - - 8.8368 0.9972 221125_WJC_METTL3_EV_vs_WT_F05.18648.18648.3 0.00134 14/56 R.GFC[160.03]FITFK[136.11]EEEPVK[136.11]K[136.11].L "sp|Q14103|HNRPD_HUMAN,tr|H0Y8G5|H0Y8G5_HUMAN,tr|H0YA96|H0YA96_HUMAN" 3 1881.9761 1.11 69665 18648 3 1881.981863 628.3326 Heterogeneous nuclear ribonucleoprotein D0 OS=Homo sapiens OX=9606 GN=HNRNPD PE=1 SV=1 6.22 3136.4 - 1.09E+06 - - - 3.058 - 2.189 0.379 - 143.4 1 2 1 0.0058 15 0 0 0 3.57E+07 3.22E+07 - - - 4.8082 1 221125_WJC_METTL3_EV_vs_WT_F05.18649.18649.4 4.43E-09 20/108 R.LGC[160.03]HPQTGFADIQGHPFFR[166.11].N sp|P41743|KPCI_HUMAN 1 2194.0406 0.86 69666 18649 4 2194.04294 549.5174 Protein kinase C iota type OS=Homo sapiens OX=9606 GN=PRKCI PE=1 SV=2 6.91 3136.5 - 727831 - - - 1.0679 - 3.151 0.62 - 255 1 2 0 0.0023 19 0 0 0 4.48E+06 5.23E+06 - - - 5.0101 1 221125_WJC_METTL3_EV_vs_WT_F05.18650.18650.3 7.11E-05 19/64 K.VTAEVVLAHLGGGSTSR[166.11].A "sp|P04843|RPN1_HUMAN,tr|F8WF32|F8WF32_HUMAN" 2 1662.8929 1.57 69667 18650 3 1662.895314 555.3049 Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit 1 OS=Homo sapiens OX=9606 GN=RPN1 PE=1 SV=1 6.72 3136.7 - 670882 - - - 1.48 - 3.705 0.486 - 501.1 1 2 0 0.0025 17 0 0 0 1.17E+07 7.43E+06 - - - 7.2664 0.9999 221125_WJC_METTL3_EV_vs_WT_F05.18654.18654.4 7.05E-07 16/84 R.VR[166.11]EEVPLELVEAHVK[136.11].K sp|Q92922|SMRC1_HUMAN 1 1763.9901 2.81 69671 18654 4 1763.991831 442.0048 SWI\SNF complex subunit SMARCC1 OS=Homo sapiens OX=9606 GN=SMARCC1 PE=1 SV=3 4.91 3137.2 - 343764 - - - 1.0068 - 2.57 0.497 - 200.8 1 2 1 0.0018 15 0 0 0 6.10E+07 2.17E+07 - - - 3.8891 1 221125_WJC_METTL3_EV_vs_WT_F05.18659.18659.2 3.63E-10 Nov-38 K.VDKIEELDQENEAALENGIK.N "sp|P43243|MATR3_HUMAN,tr|B3KM87|B3KM87_HUMAN,tr|A8MXP9|A8MXP9_HUMAN,tr|A0A0R4J2E8|A0A0R4J2E8_HUMAN,tr|D6REM6|D6REM6_HUMAN" 5 2256.1121 -1 69676 18659 2 2256.122202 1129.0633 Matrin-3 OS=Homo sapiens OX=9606 GN=MATR3 PE=1 SV=2 4 3137.8 - 112711 - - - 4.4617 - 2.768 0.636 - 240.8 1 2 1 0.0101 20 0 0 0 0.00E+00 0.00E+00 - - - 6.2384 0.9883 221125_WJC_METTL3_EV_vs_WT_F05.18663.18663.3 0.012 13/40 K.EK[136.11]FEEMIQQIK[136.11].E "sp|P48643|TCPE_HUMAN,tr|E9PCA1|E9PCA1_HUMAN,tr|B7ZAR1|B7ZAR1_HUMAN,tr|E7ENZ3|E7ENZ3_HUMAN" 4 1437.7509 0.59 69678 18663 3 1437.750473 480.2576 T-complex protein 1 subunit epsilon OS=Homo sapiens OX=9606 GN=CCT5 PE=1 SV=1 4.79 3138.3 - 2.42E+06 - - - -0.2636 - 2.235 0.165 - 342.3 1 2 1 -0.0004 11 0 0 0 2.32E+08 3.95E+08 - - - 2.6642 0.9999 221125_WJC_METTL3_EV_vs_WT_F05.18671.18671.4 2.40E-05 14/102 K.VPRPDALDNESWGFVHPR.L "sp|Q86VR2|RETR3_HUMAN,tr|K7EQI9|K7EQI9_HUMAN,tr|K7EJ42|K7EJ42_HUMAN,tr|K7EPD0|K7EPD0_HUMAN" 4 2091.0286 2.19 69684 18671 4 2091.028893 523.7644 Reticulophagy regulator 3 OS=Homo sapiens OX=9606 GN=RETREG3 PE=1 SV=1 5.38 3139.3 - 290522 - - - 0.1296 - 2.182 0.418 - 125.4 1 2 0 0.0003 18 0 0 0 4.55E+06 2.08E+06 - - - 3.1315 1 221125_WJC_METTL3_EV_vs_WT_F05.18672.18672.3 4.65E-10 17/72 R.EC[160.03]PSDEC[160.03]GAGVFMASHFDR[166.11].H "sp|P62979|RS27A_HUMAN,tr|A0A2R8Y422|A0A2R8Y422_HUMAN" 2 2180.8589 0.88 69685 18672 3 2180.858758 727.9603 Ubiquitin-40S ribosomal protein S27a OS=Homo sapiens OX=9606 GN=RPS27A PE=1 SV=2 4.31 3139.4 - 317130 - - - -0.0784 - 3.589 0.741 - 441.8 1 2 0 -0.0002 19 0 0 0 3.24E+07 3.67E+07 - - - 9.9409 0.9999 221125_WJC_METTL3_EV_vs_WT_F05.18673.18673.3 1.52E-06 17/56 R.GFC[160.03]FITFKEEEPVKK.L "sp|Q14103|HNRPD_HUMAN,tr|H0Y8G5|H0Y8G5_HUMAN,tr|H0YA96|H0YA96_HUMAN" 3 1857.9335 1.08 69686 18673 3 1857.936616 620.3184 Heterogeneous nuclear ribonucleoprotein D0 OS=Homo sapiens OX=9606 GN=HNRNPD PE=1 SV=1 6.22 3139.5 - 2.29E+06 - - - 1.6728 - 3.064 0.575 - 334.6 1 2 1 0.0031 15 0 0 0 3.57E+07 3.30E+07 - - - 7.8716 1 221125_WJC_METTL3_EV_vs_WT_F05.18674.18674.3 0.000221 21/64 K.VTAEVVLAHLGGGSTSR.A "sp|P04843|RPN1_HUMAN,tr|F8WF32|F8WF32_HUMAN" 2 1652.8846 1.57 69687 18674 3 1652.885872 551.9688 Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit 1 OS=Homo sapiens OX=9606 GN=RPN1 PE=1 SV=1 6.72 3139.6 - 1.02E+06 - - - 0.7798 - 3.794 0.529 - 753.1 1 2 0 0.0013 17 0 0 0 1.17E+07 7.43E+06 - - - 7.8061 0.9948 221125_WJC_METTL3_EV_vs_WT_F05.18675.18675.4 0.00204 13/102 K.LFQASR[166.11]PSFNLLDSPHPR[166.11].Q "sp|P46020|KPB1_HUMAN,tr|A6NMN0|A6NMN0_HUMAN,tr|A6NIT2|A6NIT2_HUMAN" 3 2101.0972 0.47 69688 18675 4 2101.096487 526.2816 "Phosphorylase b kinase regulatory subunit alpha, skeletal muscle isoform OS=Homo sapiens OX=9606 GN=PHKA1 PE=1 SV=2" 9.61 3139.7 - 377692 - - - -0.3379 - 1.843 0.226 - 96.7 1 2 0 -0.0007 18 0 0 0 2.01E+06 4.28E+06 - - - 1.4023 0.9999 221125_WJC_METTL3_EV_vs_WT_F05.18677.18677.4 0.00129 Dec-78 R.KVESLQEEIAFLKK.L "sp|P08670|VIME_HUMAN,tr|B0YJC5|B0YJC5_HUMAN,tr|B0YJC4|B0YJC4_HUMAN" 3 1660.94 1.74 69690 18677 4 1660.939875 416.2423 Vimentin OS=Homo sapiens OX=9606 GN=VIM PE=1 SV=4 6.23 3140 - 204253 - - - -0.059 - 2.67 0.389 - 146.6 1 2 0 -0.0001 14 0 0 0 3.74E+08 2.15E+08 - - - 2.9692 0.9999 221125_WJC_METTL3_EV_vs_WT_F05.18679.18679.4 2.68E-07 14/78 R.K[136.11]VESLQEEIAFLK[136.11]K[136.11].L "sp|P08670|VIME_HUMAN,tr|B0YJC5|B0YJC5_HUMAN,tr|B0YJC4|B0YJC4_HUMAN" 3 1684.9826 1.7 69692 18679 4 1684.982959 422.2529 Vimentin OS=Homo sapiens OX=9606 GN=VIM PE=1 SV=4 6.23 3140.2 - 183636 - - - 0.2291 - 2.83 0.437 - 178.6 1 2 0 0.0004 14 0 0 0 3.60E+08 2.11E+08 - - - 3.4081 0.9948 221125_WJC_METTL3_EV_vs_WT_F05.18682.18682.3 0.000307 14/40 K.EKFEEMIQQIK.E "sp|P48643|TCPE_HUMAN,tr|E9PCA1|E9PCA1_HUMAN,tr|B7ZAR1|B7ZAR1_HUMAN,tr|E7ENZ3|E7ENZ3_HUMAN" 4 1421.7225 0.59 69693 18682 3 1421.721832 474.9148 T-complex protein 1 subunit epsilon OS=Homo sapiens OX=9606 GN=CCT5 PE=1 SV=1 4.79 3140.6 - 3.92E+06 - - - -0.4361 - 2.234 0.215 - 334.4 1 2 1 -0.0006 11 0 0 0 2.32E+08 3.95E+08 - - - 3.2203 0.9987 221125_WJC_METTL3_EV_vs_WT_F05.18683.18683.2 3.60E-06 13/20 K.EK[136.11]FEEMIQQIK[136.11].E "sp|P48643|TCPE_HUMAN,tr|E9PCA1|E9PCA1_HUMAN,tr|B7ZAR1|B7ZAR1_HUMAN,tr|E7ENZ3|E7ENZ3_HUMAN" 4 1437.7509 0.6 69694 18683 2 1437.750067 719.8827 T-complex protein 1 subunit epsilon OS=Homo sapiens OX=9606 GN=CCT5 PE=1 SV=1 4.79 3140.7 - 2.65E+06 - - - -0.546 - 2.347 0.493 - 465.2 1 2 1 -0.0008 11 0 0 0 8.89E+07 1.47E+08 - - - 4.99 0.998 221125_WJC_METTL3_EV_vs_WT_F05.18684.18684.2 0.00359 20-Dec K.EKFEEMIQQIK.E "sp|P48643|TCPE_HUMAN,tr|E9PCA1|E9PCA1_HUMAN,tr|B7ZAR1|B7ZAR1_HUMAN,tr|E7ENZ3|E7ENZ3_HUMAN" 4 1421.7225 0.6 69695 18684 2 1421.721207 711.8685 T-complex protein 1 subunit epsilon OS=Homo sapiens OX=9606 GN=CCT5 PE=1 SV=1 4.79 3140.8 - 1.48E+06 - - - -0.8757 - 2.655 0.369 - 302.8 1 2 1 -0.0012 11 0 0 0 8.89E+07 1.47E+08 - - - 4.4076 0.9999 221125_WJC_METTL3_EV_vs_WT_F05.18685.18685.3 3.33E-06 16/76 R.FSGVPDRFSGSGSGTDFTLK.L "sp|A2NJV5|KV229_HUMAN,sp|A0A075B6S2|KVD29_HUMAN,sp|A0A0A0MRZ7|KVD26_HUMAN" 3 2060.9803 999 69696 18685 3 2060.980869 688.0007 Immunoglobulin kappa variable 2-29 OS=Homo sapiens OX=9606 GN=IGKV2-29 PE=3 SV=2 5.96 3140.9 - 804783 - - - 0.2596 - 2.907 0.513 - 229.1 1 2 1 0.0005 20 0 0 0 2.27E+09 0.00E+00 - - - 6.8482 0.9999 221125_WJC_METTL3_EV_vs_WT_F05.18686.18686.4 4.78E-07 22/108 R.IHYIGQNEPELLVAHAYTR.Y "sp|P30519|HMOX2_HUMAN,tr|I3L159|I3L159_HUMAN,tr|A0A087WT44|A0A087WT44_HUMAN,tr|I3L1F5|I3L1F5_HUMAN" 4 2223.1437 0.95 69697 18686 4 2223.151938 556.7932 Heme oxygenase 2 OS=Homo sapiens OX=9606 GN=HMOX2 PE=1 SV=2 6 3141.1 - 679807 - - - 3.7272 - 3.993 0.514 - 519.2 1 2 0 0.0083 19 0 0 0 7.94E+06 8.39E+06 - - - 4.1659 1 221125_WJC_METTL3_EV_vs_WT_F05.18687.18687.3 9.69E-12 21/72 R.EC[160.03]PSDEC[160.03]GAGVFMASHFDR.H "sp|P62979|RS27A_HUMAN,tr|A0A2R8Y422|A0A2R8Y422_HUMAN" 2 2170.8507 0.88 69698 18687 3 2170.849226 724.6242 Ubiquitin-40S ribosomal protein S27a OS=Homo sapiens OX=9606 GN=RPS27A PE=1 SV=2 4.31 3141.2 - 642210 - - - -0.6601 - 3.6 0.748 - 597.7 1 2 0 -0.0014 19 0 0 0 3.24E+07 3.67E+07 - - - 10.0261 1 221125_WJC_METTL3_EV_vs_WT_F05.18691.18691.3 2.54E-08 21/52 R.KVESLQEEIAFLKK.L "sp|P08670|VIME_HUMAN,tr|B0YJC5|B0YJC5_HUMAN,tr|B0YJC4|B0YJC4_HUMAN" 3 1660.94 1.75 69700 18691 3 1660.940192 554.6539 Vimentin OS=Homo sapiens OX=9606 GN=VIM PE=1 SV=4 6.23 3141.7 - 2.55E+06 - - - 0.1319 - 3.971 0.628 - 737.3 1 2 0 0.0002 14 0 0 0 5.73E+08 3.28E+08 - - - 9.2063 0.9797 221125_WJC_METTL3_EV_vs_WT_F05.18696.18696.2 6.55E-05 30-Aug R.SESPQPAPDWGSQR[166.11]PF.H "sp|O00165|HAX1_HUMAN,tr|E9PIQ7|E9PIQ7_HUMAN" 2 1794.8201 1.71 69705 18696 2 1794.824101 898.4173 HCLS1-associated protein X-1 OS=Homo sapiens OX=9606 GN=HAX1 PE=1 SV=2 4.37 3142.4 - 155682 - - - 2.2392 - 1.838 0.572 - 127.8 1 1 0 0.004 16 0 0 0 8.59E+06 5.02E+06 - - - 4.761 1 221125_WJC_METTL3_EV_vs_WT_F05.18701.18701.3 1.33E-08 20/52 R.K[136.11]VESLQEEIAFLK[136.11]K[136.11].L "sp|P08670|VIME_HUMAN,tr|B0YJC5|B0YJC5_HUMAN,tr|B0YJC4|B0YJC4_HUMAN" 3 1684.9826 1.74 69708 18701 3 1684.982163 562.6681 Vimentin OS=Homo sapiens OX=9606 GN=VIM PE=1 SV=4 6.23 3143.1 - 5.26E+06 - - - -0.2433 - 3.42 0.612 - 623.3 1 2 0 -0.0004 14 0 0 0 5.61E+08 3.23E+08 - - - 8.6309 0.9999 221125_WJC_METTL3_EV_vs_WT_F05.18705.18705.3 2.68E-05 Nov-64 R.K[136.11]SEAPSYIAVPDPSVLK[136.11].Q sp|Q9UQR0|SCML2_HUMAN 1 1815.9953 0.88 69712 18705 3 1815.997258 606.339 Sex comb on midleg-like protein 2 OS=Homo sapiens OX=9606 GN=SCML2 PE=1 SV=1 6.07 3143.6 - 315748 - - - 1.0694 - 2.175 0.469 - 115.5 1 2 0 0.0019 17 0 0 0 3.75E+06 4.26E+06 - - - 5.7314 1 221125_WJC_METTL3_EV_vs_WT_F05.18706.18706.2 3.87E-11 15/42 K.AASADSTTEGTPADGFTVLSTK[136.11].S sp|O75367|H2AY_HUMAN 1 2134.0157 1.32 69713 18706 2 2134.01482 1068.0151 Core histone macro-H2A.1 OS=Homo sapiens OX=9606 GN=MACROH2A1 PE=1 SV=4 4.03 3143.7 - 245206 - - - -0.4231 - 2.968 0.76 - 434.2 1 2 0 -0.0009 22 0 0 0 4.58E+06 3.48E+06 - - - 7.3287 1 221125_WJC_METTL3_EV_vs_WT_F05.18707.18707.2 6.23E-12 Dec-42 K.AASADSTTEGTPADGFTVLSTK.S sp|O75367|H2AY_HUMAN 1 2126.0015 1.32 69714 18707 2 2125.999833 1064.008 Core histone macro-H2A.1 OS=Homo sapiens OX=9606 GN=MACROH2A1 PE=1 SV=4 4.03 3143.8 - 238914 - - - -0.7949 - 3.047 0.721 - 232.3 1 2 0 -0.0017 22 0 0 0 4.58E+06 3.48E+06 - - - 7.105 1 221125_WJC_METTL3_EV_vs_WT_F05.18712.18712.3 1.15E-08 18/64 K.ITNEKGEC[160.03]IVSDFTIGR.K "sp|P52948|NUP98_HUMAN,tr|A0A3B3ITD8|A0A3B3ITD8_HUMAN" 2 1937.9517 1.58 69717 18712 3 1937.949879 646.9912 Nuclear pore complex protein Nup98-Nup96 OS=Homo sapiens OX=9606 GN=NUP98 PE=1 SV=4 4.68 3144.5 - 4.34E+06 - - - -0.9278 - 3.476 0.581 - 305.7 1 2 1 -0.0018 17 0 0 0 5.71E+07 3.60E+07 - - - 8.1646 0.9997 221125_WJC_METTL3_EV_vs_WT_F05.18713.18713.3 0.000106 13/52 R.DKLTVEELEQFQSK.K "sp|O15504|NUP42_HUMAN,tr|C9JYA1|C9JYA1_HUMAN" 2 1692.857 2.25 69718 18713 3 1692.855498 565.293 Nucleoporin NUP42 OS=Homo sapiens OX=9606 GN=NUP42 PE=1 SV=1 4.41 3144.6 - 1.40E+06 - - - -0.9056 - 2.255 0.458 - 222.5 1 2 1 -0.0015 14 0 0 0 1.91E+07 8.49E+06 - - - 5.8068 0.9999 221125_WJC_METTL3_EV_vs_WT_F05.18714.18714.3 6.48E-05 14/68 R.GLRPLELPAVPATEPGNK.K sp|Q9BUA3|SPNDC_HUMAN 1 1858.0312 4.87 69719 18714 3 1858.030001 620.351 Spindlin interactor and repressor of chromatin-binding protein OS=Homo sapiens OX=9606 GN=SPINDOC PE=1 SV=3 6.14 3144.6 - 1.10E+06 - - - -0.6711 - 2.3 0.404 - 218.1 1 2 0 -0.0012 18 0 0 0 2.34E+07 4.80E+06 - - - 5.1179 0.9913 221125_WJC_METTL3_EV_vs_WT_F05.18715.18715.2 9.57E-05 30-Dec R.SESPQPAPDWGSQRPF.H "sp|O00165|HAX1_HUMAN,tr|E9PIQ7|E9PIQ7_HUMAN" 2 1784.8118 1.71 69720 18715 2 1784.809349 893.4132 HCLS1-associated protein X-1 OS=Homo sapiens OX=9606 GN=HAX1 PE=1 SV=2 4.37 3144.8 - 363448 - - - -1.38 - 2.18 0.574 - 245 1 1 0 -0.0025 16 0 0 0 8.59E+06 5.02E+06 - - - 5.1958 0.9999 221125_WJC_METTL3_EV_vs_WT_F05.18716.18716.3 7.53E-05 Oct-80 K.SEYTQPTPIQC[160.03]QGVPVALSGR[166.11].D "sp|Q86XP3|DDX42_HUMAN,tr|A0A0A0MSJ0|A0A0A0MSJ0_HUMAN" 2 2297.135 0.95 69721 18716 3 2297.134997 766.7189 ATP-dependent RNA helicase DDX42 OS=Homo sapiens OX=9606 GN=DDX42 PE=1 SV=1 5.72 3144.9 - 336063 - - - 0.02 - 2.165 0.485 - 58 1 2 0 0 21 0 0 0 4.45E+06 4.70E+06 - - - 5.7991 1 221125_WJC_METTL3_EV_vs_WT_F05.18719.18719.2 1.93E-07 15/38 R.FSGVPDRFSGSGSGTDFTLK.L "sp|A2NJV5|KV229_HUMAN,sp|A0A075B6S2|KVD29_HUMAN,sp|A0A0A0MRZ7|KVD26_HUMAN" 3 2060.9803 999 69724 18719 2 2060.984521 1031.4974 Immunoglobulin kappa variable 2-29 OS=Homo sapiens OX=9606 GN=IGKV2-29 PE=3 SV=2 5.96 3145.3 - 274221 - - - 2.0316 - 3.088 0.592 - 262.6 1 2 1 0.0042 20 0 0 0 3.86E+07 0.00E+00 - - - 6.1843 0.9968 221125_WJC_METTL3_EV_vs_WT_F05.18724.18724.4 0.0115 13/84 R.GFC[160.03]FITFKEEEPVKK.L "sp|Q14103|HNRPD_HUMAN,tr|H0Y8G5|H0Y8G5_HUMAN,tr|H0YA96|H0YA96_HUMAN" 3 1857.9335 1.18 69727 18724 4 1857.932323 465.4907 Heterogeneous nuclear ribonucleoprotein D0 OS=Homo sapiens OX=9606 GN=HNRNPD PE=1 SV=1 6.22 3146 - 1.47E+06 - - - -0.6378 - 1.936 0.308 - 94.8 1 2 1 -0.0012 15 0 0 0 9.07E+07 7.72E+07 - - - 2.1429 1 221125_WJC_METTL3_EV_vs_WT_F05.18727.18727.2 2.64E-07 26-Dec K.EEYITSALESTEEK.L "sp|P52732|KIF11_HUMAN,tr|A0A7I2YQY4|A0A7I2YQY4_HUMAN,tr|A0A7I2V3A9|A0A7I2V3A9_HUMAN,tr|A0A7I2V3V3|A0A7I2V3V3_HUMAN" 4 1627.7465 10.5 69730 18727 2 1627.743667 814.8805 Kinesin-like protein KIF11 OS=Homo sapiens OX=9606 GN=KIF11 PE=1 SV=2 3.98 3146.2 - 740461 - - - -1.7269 - 2.649 0.632 - 388.7 1 2 0 -0.0028 14 0 0 0 1.29E+07 1.23E+06 - - - 6.1527 1 221125_WJC_METTL3_EV_vs_WT_F05.18731.18731.2 2.69E-07 Oct-36 K.VNGNPHSTPVSGPPAFLTQ.G sp|Q96I24|FUBP3_HUMAN 1 1918.9537 - 69734 18731 2 1918.954505 960.4841 Far upstream element-binding protein 3 OS=Homo sapiens OX=9606 GN=FUBP3 PE=1 SV=2 6.71 3146.8 - 398617 - - - 0.406 - 2.657 0.607 - 183.3 1 1 0 0.0008 19 0 0 0 - - - - - 5.9265 0.9287 221125_WJC_METTL3_EV_vs_WT_F05.18734.18734.2 0.681 14-Oct Q.EEIAFLK[136.11]K[136.11].L "sp|P08670|VIME_HUMAN,sp|P17661|DESM_HUMAN,tr|B0YJC5|B0YJC5_HUMAN,tr|B0YJC4|B0YJC4_HUMAN" 4 992.5877 1.78 69735 18734 2 992.585202 497.3011 Vimentin OS=Homo sapiens OX=9606 GN=VIM PE=1 SV=4 6.24 3147.2 - 997280 - - - -2.5499 - 1.979 0.293 - 350.4 1 1 0 -0.0025 8 0 0 0 2.10E+07 1.18E+07 - - - 3.263 1 221125_WJC_METTL3_EV_vs_WT_F05.18736.18736.3 6.64E-08 15/84 K.IGGDAATTVNNSTPDFGFGGQK[136.11].R "sp|Q92945|FUBP2_HUMAN,tr|M0R0I5|M0R0I5_HUMAN,tr|M0R0C6|M0R0C6_HUMAN,tr|A0A087WTP3|A0A087WTP3_HUMAN" 4 2161.0167 1.19 69737 18736 3 2161.015109 721.3462 Far upstream element-binding protein 2 OS=Homo sapiens OX=9606 GN=KHSRP PE=1 SV=4 4.21 3147.4 - 3.52E+06 - - - -0.7483 - 2.694 0.554 - 206.7 1 2 0 -0.0016 22 0 0 0 5.10E+07 4.28E+07 - - - 7.0657 1 221125_WJC_METTL3_EV_vs_WT_F05.18737.18737.3 2.67E-08 22/80 M.IPGGLSEAKPATPEIQEIVDK.V "sp|P01040|CYTA_HUMAN,tr|C9J0E4|C9J0E4_HUMAN" 2 2191.1736 999 69738 18737 3 2191.169649 731.3985 Cystatin-A OS=Homo sapiens OX=9606 GN=CSTA PE=1 SV=1 4.41 3147.5 - 822602 - - - -1.8095 - 4.374 0.589 - 577 1 2 0 -0.004 21 0 0 0 2.86E+07 0.00E+00 - - - 8.6435 1 221125_WJC_METTL3_EV_vs_WT_F05.18738.18738.2 7.03E-06 16/26 R.KVESLQEEIAFLKK.L "sp|P08670|VIME_HUMAN,tr|B0YJC5|B0YJC5_HUMAN,tr|B0YJC4|B0YJC4_HUMAN" 3 1660.94 2.52 69739 18738 2 1660.937947 831.4773 Vimentin OS=Homo sapiens OX=9606 GN=VIM PE=1 SV=4 6.23 3147.6 - 664606 - - - -1.2198 - 3.891 0.603 - 517 1 2 0 -0.002 14 0 0 0 7.67E+06 3.04E+06 - - - 6.9036 1 221125_WJC_METTL3_EV_vs_WT_F05.18739.18739.2 0.0136 14/26 K.SQSSSAEQSFLFSR.E sp|Q9Y6D9|MD1L1_HUMAN 1 1559.7216 1.62 69740 18739 2 1559.72005 780.8681 Mitotic spindle assembly checkpoint protein MAD1 OS=Homo sapiens OX=9606 GN=MAD1L1 PE=1 SV=2 5.72 3147.7 - 321170 - - - -0.9938 - 2.997 0.569 - 838.9 1 2 0 -0.0015 14 0 0 0 7.29E+06 4.49E+06 - - - 5.9975 1 221125_WJC_METTL3_EV_vs_WT_F05.18745.18745.3 2.09E-11 24/76 R.PSPAISVSVSAPAFYAPQKK.F "sp|Q15942|ZYX_HUMAN,tr|H0Y2Y8|H0Y2Y8_HUMAN,tr|C9IZ41|C9IZ41_HUMAN" 3 2044.0993 5.62 69744 18745 3 2044.102025 682.3737 Zyxin OS=Homo sapiens OX=9606 GN=ZYX PE=1 SV=1 9.73 3148.5 - 1.65E+06 - - - 1.3199 - 4.033 0.626 - 740.3 1 1 0 0.0027 20 0 0 0 3.94E+07 7.02E+06 - - - 8.9017 1 221125_WJC_METTL3_EV_vs_WT_F05.18746.18746.2 7.26E-14 22/42 K.IGGDAATTVNNSTPDFGFGGQK.R "sp|Q92945|FUBP2_HUMAN,tr|M0R0I5|M0R0I5_HUMAN,tr|M0R0C6|M0R0C6_HUMAN,tr|A0A087WTP3|A0A087WTP3_HUMAN" 4 2153.0025 1.43 69745 18746 2 2153.000382 1077.5085 Far upstream element-binding protein 2 OS=Homo sapiens OX=9606 GN=KHSRP PE=1 SV=4 4.21 3148.6 - 919774 - - - -0.9958 - 3.95 0.749 - 1103.8 1 2 0 -0.0021 22 0 0 0 1.33E+07 9.30E+06 - - - 7.9498 0.9893 221125_WJC_METTL3_EV_vs_WT_F05.18748.18748.2 3.64E-06 26-Nov L.SSASTSSHNLQSIF.- tr|D6RBS2|D6RBS2_HUMAN 1 1464.6845 - 69747 18748 2 1464.683439 733.3495 Matrin-3 (Fragment) OS=Homo sapiens OX=9606 GN=MATR3 PE=1 SV=1 6.46 3148.9 - 884566 - - - -0.7148 - 1.984 0.484 - 353.3 1 1 0 -0.001 14 0 0 0 - - - - - 4.3348 1 221125_WJC_METTL3_EV_vs_WT_F05.18751.18751.2 5.20E-16 21/42 K.IGGDAATTVNNSTPDFGFGGQK[136.11].R "sp|Q92945|FUBP2_HUMAN,tr|M0R0I5|M0R0I5_HUMAN,tr|M0R0C6|M0R0C6_HUMAN,tr|A0A087WTP3|A0A087WTP3_HUMAN" 4 2161.0167 1.43 69750 18751 2 2161.011504 1081.5156 Far upstream element-binding protein 2 OS=Homo sapiens OX=9606 GN=KHSRP PE=1 SV=4 4.21 3149.2 - 723181 - - - -2.4165 - 4.011 0.732 - 831.8 1 2 0 -0.0052 22 0 0 0 1.33E+07 9.30E+06 - - - 7.8609 0.9998 221125_WJC_METTL3_EV_vs_WT_F05.18752.18752.2 4.74E-08 28-Dec K.SSGVPVDGFYTEEVR[166.11].Q "sp|Q9BSD7|NTPCR_HUMAN,tr|Q5TDF0|Q5TDF0_HUMAN" 2 1650.7765 0.66 69751 18752 2 1650.77368 826.3955 Cancer-related nucleoside-triphosphatase OS=Homo sapiens OX=9606 GN=NTPCR PE=1 SV=1 4.14 3149.4 - 720096 - - - -1.6998 - 2.072 0.598 - 358.2 1 2 0 -0.0028 15 0 0 0 7.07E+06 1.07E+07 - - - 5.248 0.9999 221125_WJC_METTL3_EV_vs_WT_F05.18753.18753.2 1.83E-06 28-Nov K.SSGVPVDGFYTEEVR.Q "sp|Q9BSD7|NTPCR_HUMAN,tr|Q5TDF0|Q5TDF0_HUMAN" 2 1640.7682 0.55 69752 18753 2 1640.767356 821.3914 Cancer-related nucleoside-triphosphatase OS=Homo sapiens OX=9606 GN=NTPCR PE=1 SV=1 4.14 3149.5 - 475637 - - - -0.5241 - 1.983 0.589 - 250.8 1 2 0 -0.0009 15 0 0 0 7.07E+06 1.29E+07 - - - 5.0742 0.9799 221125_WJC_METTL3_EV_vs_WT_F05.18754.18754.3 0.000144 16/76 M.R[166.11]ILSAENIPNLPPGGGLAGK[136.11].R "sp|O75688|PPM1B_HUMAN,tr|B8ZZF0|B8ZZF0_HUMAN,tr|A0A3B3IS24|A0A3B3IS24_HUMAN,tr|C9JIR6|C9JIR6_HUMAN" 4 1991.1283 4.3 69753 18754 3 1991.121285 664.7167 Protein phosphatase 1B OS=Homo sapiens OX=9606 GN=PPM1B PE=1 SV=1 8.75 3149.6 - 458036 - - - -3.5131 - 3.075 0.451 - 205.3 1 1 0 -0.007 20 0 0 0 5.46E+07 1.27E+07 - - - 6.2914 1 221125_WJC_METTL3_EV_vs_WT_F05.18758.18758.3 2.16E-07 24/84 K.IGGDAATTVNNSTPDFGFGGQK.R "sp|Q92945|FUBP2_HUMAN,tr|M0R0I5|M0R0I5_HUMAN,tr|M0R0C6|M0R0C6_HUMAN,tr|A0A087WTP3|A0A087WTP3_HUMAN" 4 2153.0025 1.19 69755 18758 3 2152.999549 718.6748 Far upstream element-binding protein 2 OS=Homo sapiens OX=9606 GN=KHSRP PE=1 SV=4 4.21 3150.2 - 5.86E+06 - - - -1.3827 - 3.485 0.59 - 563.1 1 2 0 -0.003 22 0 0 0 5.10E+07 4.28E+07 - - - 8.077 1 221125_WJC_METTL3_EV_vs_WT_F05.18759.18759.3 1.22E-15 23/80 R.PVELSDR[166.11]ETLLNSATTSLNSK[136.11].V sp|P50991|TCPD_HUMAN 1 2292.1928 0.14 69756 18759 3 2292.189798 765.0715 T-complex protein 1 subunit delta OS=Homo sapiens OX=9606 GN=CCT4 PE=1 SV=4 4.68 3150.3 - 1.10E+06 - - - -1.3053 - 4.391 0.671 - 470.6 1 1 1 -0.003 21 0 0 0 1.38E+06 1.01E+07 - - - 9.5673 0.9926 221125_WJC_METTL3_EV_vs_WT_F05.18761.18761.4 0.00149 11/114 R.FSGVPDRFSGSGSGTDFTLK.L "sp|A2NJV5|KV229_HUMAN,sp|A0A075B6S2|KVD29_HUMAN,sp|A0A0A0MRZ7|KVD26_HUMAN" 3 2060.9803 12.87 69758 18761 4 2060.976042 516.2524 Immunoglobulin kappa variable 2-29 OS=Homo sapiens OX=9606 GN=IGKV2-29 PE=3 SV=2 5.96 3150.5 - 735031 - - - -2.0825 - 1.772 0.294 - 71.5 1 2 1 -0.0043 20 0 0 0 4.94E+06 3.84E+05 - - - 1.9751 1 221125_WJC_METTL3_EV_vs_WT_F05.18763.18763.2 5.99E-11 14/34 K.QTIDNSQGAYQEAFDISK[136.11].K sp|P27348|1433T_HUMAN 1 2021.9422 1.13 69760 18763 2 2021.940458 1011.9784 14-3-3 protein theta OS=Homo sapiens OX=9606 GN=YWHAQ PE=1 SV=1 4.03 3150.8 - 670339 - - - -0.8437 - 3.016 0.629 - 555 1 2 0 -0.0017 18 0 0 0 8.07E+06 7.14E+06 - - - 6.4003 0.9999 221125_WJC_METTL3_EV_vs_WT_F05.18764.18764.3 1.48E-05 13/44 R.EHALLAYTLGVK[136.11].Q "sp|Q05639|EF1A2_HUMAN,sp|P68104|EF1A1_HUMAN,sp|Q5VTE0|EF1A3_HUMAN,tr|A0A2R8Y488|A0A2R8Y488_HUMAN,tr|A0A7I2V659|A0A7I2V659_HUMAN,tr|A0A7I2V3H3|A0A7I2V3H3_HUMAN,tr|A0A2U3TZH3|A0A2U3TZH3_HUMAN,tr|A0A7I2V5N4|A0A7I2V5N4_HUMAN,tr|A0A087WVQ9|A0A087WVQ9_HUMAN,tr|A0A087WV01|A0A087WV01_HUMAN,tr|A0A2R8Y660|A0A2R8Y660_HUMAN" 11 1321.7485 2.77 69761 18764 3 1321.745247 441.5901 Elongation factor 1-alpha 2 OS=Homo sapiens OX=9606 GN=EEF1A2 PE=1 SV=1 6.85 3150.9 - 556417 - - - -2.4891 - 2.707 0.477 - 291.9 1 2 0 -0.0033 12 0 0 0 1.80E+07 6.51E+06 - - - 6.6175 1 221125_WJC_METTL3_EV_vs_WT_F05.18770.18770.3 4.36E-09 16/68 K.QTIDNSQGAYQEAFDISK.K sp|P27348|1433T_HUMAN 1 2013.928 1.4 69765 18770 3 2013.923526 672.3166 14-3-3 protein theta OS=Homo sapiens OX=9606 GN=YWHAQ PE=1 SV=1 4.03 3151.8 - 1.19E+06 - - - -2.2037 - 3.381 0.617 - 282.1 1 2 0 -0.0044 18 0 0 0 1.32E+07 9.43E+06 - - - 8.4511 1 221125_WJC_METTL3_EV_vs_WT_F05.18771.18771.3 2.45E-08 16/68 K.QTIDNSQGAYQEAFDISK[136.11].K sp|P27348|1433T_HUMAN 1 2021.9422 1.4 69766 18771 3 2021.939837 674.988 14-3-3 protein theta OS=Homo sapiens OX=9606 GN=YWHAQ PE=1 SV=1 4.03 3151.9 - 1.25E+06 - - - -1.1509 - 3.298 0.499 - 377.6 1 2 0 -0.0023 18 0 0 0 1.32E+07 9.43E+06 - - - 7.0742 0.9998 221125_WJC_METTL3_EV_vs_WT_F05.18773.18773.3 3.05E-07 13/40 K.LKVPEWVDTVK.L "sp|P39019|RS19_HUMAN,tr|M0R140|M0R140_HUMAN,tr|M0R2L9|M0R2L9_HUMAN,tr|M0QYF7|M0QYF7_HUMAN" 4 1312.7391 1.16 69768 18773 3 1312.736245 438.587 40S ribosomal protein S19 OS=Homo sapiens OX=9606 GN=RPS19 PE=1 SV=2 6.07 3152.1 - 980781 - - - -2.1657 - 2.671 0.492 - 270 1 2 1 -0.0028 11 0 0 0 1.08E+07 9.34E+06 - - - 6.8155 1 221125_WJC_METTL3_EV_vs_WT_F05.18774.18774.2 1.40E-11 16/34 K.QTIDNSQGAYQEAFDISK.K sp|P27348|1433T_HUMAN 1 2013.928 1.13 69769 18774 2 2013.925737 1007.9713 14-3-3 protein theta OS=Homo sapiens OX=9606 GN=YWHAQ PE=1 SV=1 4.03 3152.3 - 912730 - - - -1.1058 - 3.47 0.696 - 858.1 1 2 0 -0.0022 18 0 0 0 8.07E+06 7.14E+06 - - - 7.2398 1 221125_WJC_METTL3_EV_vs_WT_F05.18779.18779.3 2.24E-10 20/64 K.EGQEEVLKEVVESEGER.K "sp|Q8TAQ2|SMRC2_HUMAN,tr|F8VXC8|F8VXC8_HUMAN" 2 1944.9276 1.61 69774 18779 3 1944.927254 649.3165 SWI\SNF complex subunit SMARCC2 OS=Homo sapiens OX=9606 GN=SMARCC2 PE=1 SV=1 4.12 3152.9 - 332446 - - - -0.1933 - 3.005 0.633 - 612.7 1 2 1 -0.0004 17 0 0 0 1.27E+07 7.86E+06 - - - 8.3769 0.9989 221125_WJC_METTL3_EV_vs_WT_F05.18781.18781.3 0.00755 Nov-44 R.QLFHPEQLITGK.E "sp|Q9NY65|TBA8_HUMAN,sp|Q6PEY2|TBA3E_HUMAN,sp|P0DPH7|TBA3C_HUMAN,sp|Q71U36|TBA1A_HUMAN,sp|P0DPH8|TBA3D_HUMAN,sp|Q9H853|TBA4B_HUMAN,sp|P68366|TBA4A_HUMAN,sp|P68363|TBA1B_HUMAN,sp|Q9BQE3|TBA1C_HUMAN,tr|C9JJQ8|C9JJQ8_HUMAN,tr|F8VS66|F8VS66_HUMAN,tr|F8VWV9|F8VWV9_HUMAN,tr|F8VRZ4|F8VRZ4_HUMAN,tr|F8VVB9|F8VVB9_HUMAN,tr|C9JQ00|C9JQ00_HUMAN,tr|C9JEV8|C9JEV8_HUMAN,tr|A0A7P0TA31|A0A7P0TA31_HUMAN,tr|A0A1W2PQM2|A0A1W2PQM2_HUMAN,tr|F5H5D3|F5H5D3_HUMAN,tr|C9J2C0|C9J2C0_HUMAN,tr|C9K0S6|C9K0S6_HUMAN,tr|C9JDL2|C9JDL2_HUMAN,tr|F8VQQ4|F8VQQ4_HUMAN,tr|F8VX09|F8VX09_HUMAN,tr|A0A7P0T945|A0A7P0T945_HUMAN" 25 1409.7667 0.48 69776 18781 3 1409.763886 470.9295 Tubulin alpha-8 chain OS=Homo sapiens OX=9606 GN=TUBA8 PE=1 SV=1 6.75 3153.2 - 241359 - - - -1.9961 - 1.958 0.294 - 144.2 1 2 0 -0.0028 12 0 0 0 5.75E+06 1.20E+07 - - - 3.6795 1 221125_WJC_METTL3_EV_vs_WT_F05.18786.18786.3 1.15E-13 23/72 R.SIQETLGESGSLLPNKLNK.L sp|Q96BP2|CHCH1_HUMAN 1 2027.0899 1.32 69779 18786 3 2027.089948 676.7039 Coiled-coil-helix-coiled-coil-helix domain-containing protein 1 OS=Homo sapiens OX=9606 GN=CHCHD1 PE=1 SV=1 5.86 3153.8 - 2.25E+06 - - - 0.0311 - 3.855 0.683 - 428.1 1 2 1 0.0001 19 0 0 0 1.66E+09 1.25E+09 - - - 9.4699 0.9996 221125_WJC_METTL3_EV_vs_WT_F05.18787.18787.3 0.00198 Dec-48 K.DKWSNFDPTGLER.A "sp|Q5T9A4|ATD3B_HUMAN,sp|Q9NVI7|ATD3A_HUMAN,tr|A0A5K1VW56|A0A5K1VW56_HUMAN,tr|H0Y2W2|H0Y2W2_HUMAN" 4 1563.7318 0.98 69780 18787 3 1563.731781 522.2512 ATPase family AAA domain-containing protein 3B OS=Homo sapiens OX=9606 GN=ATAD3B PE=1 SV=1 4.56 3153.8 - 2.02E+06 - - - 0.0064 - 2.066 0.428 - 156.1 1 2 1 0 13 0 0 0 2.04E+07 2.09E+07 - - - 5.2791 0.9999 221125_WJC_METTL3_EV_vs_WT_F05.18789.18789.2 0.000475 13/22 K.LNDLEDALQQAK.E sp|P04264|K2C1_HUMAN 1 1356.6885 4.89 69782 18789 2 1356.689278 679.3515 "Keratin, type II cytoskeletal 1 OS=Homo sapiens OX=9606 GN=KRT1 PE=1 SV=6" 4.03 3154.1 - 982176 - - - 0.5668 - 2.856 0.392 - 724.1 1 2 0 0.0008 12 0 0 0 7.86E+07 1.61E+07 - - - 4.6973 0.9999 221125_WJC_METTL3_EV_vs_WT_F05.18790.18790.3 1.62E-05 13/40 K.LK[136.11]VPEWVDTVK[136.11].L "sp|P39019|RS19_HUMAN,tr|M0R140|M0R140_HUMAN,tr|M0R2L9|M0R2L9_HUMAN,tr|M0QYF7|M0QYF7_HUMAN" 4 1328.7675 1.16 69783 18790 3 1328.766511 443.9298 40S ribosomal protein S19 OS=Homo sapiens OX=9606 GN=RPS19 PE=1 SV=2 6.07 3154.2 - 840233 - - - -0.7353 - 2.532 0.473 - 245.2 1 2 1 -0.001 11 0 0 0 1.08E+07 9.34E+06 - - - 6.4524 1 221125_WJC_METTL3_EV_vs_WT_F05.18792.18792.3 2.22E-08 17/84 K.EAQDAPGLDPQGAADC[160.03]AQGVLR.Q "sp|P39880|CUX1_HUMAN,tr|A0A2R8Y852|A0A2R8Y852_HUMAN,tr|A0A2R8YDI1|A0A2R8YDI1_HUMAN" 3 2238.0335 1.83 69785 18792 3 2238.031504 747.0184 Homeobox protein cut-like 1 OS=Homo sapiens OX=9606 GN=CUX1 PE=1 SV=3 3.84 3154.4 - 650263 - - - -0.8959 - 3.357 0.571 - 281.8 1 2 0 -0.002 22 0 0 0 6.59E+06 3.59E+06 - - - 7.7767 0.9987 221125_WJC_METTL3_EV_vs_WT_F05.18796.18796.3 0.003 Oct-56 R.FKEQLTPSQIMSLEK.E "sp|Q00059|TFAM_HUMAN,tr|H7BYN3|H7BYN3_HUMAN" 2 1777.9284 1.48 69789 18796 3 1777.928171 593.6501 "Transcription factor A, mitochondrial OS=Homo sapiens OX=9606 GN=TFAM PE=1 SV=1" 6.14 3155 - 255307 - - - -0.1412 - 1.896 0.367 - 97.3 1 2 1 -0.0003 15 0 0 0 2.35E+06 1.58E+06 - - - 4.301 0.9993 221125_WJC_METTL3_EV_vs_WT_F05.18797.18797.3 9.91E-05 Sep-44 R.LLKEYQELMNVK.L "sp|P48668|K2C6C_HUMAN,sp|P04259|K2C6B_HUMAN,sp|P02538|K2C6A_HUMAN" 3 1506.8116 999 69790 18797 3 1506.809485 503.2778 "Keratin, type II cytoskeletal 6C OS=Homo sapiens OX=9606 GN=KRT6C PE=1 SV=3" 6.14 3155.1 - 247710 - - - -1.4043 - 1.805 0.429 - 96.1 1 2 1 -0.0021 12 0 0 0 4.86E+06 0.00E+00 - - - 4.9593 0.9998 221125_WJC_METTL3_EV_vs_WT_F05.18801.18801.3 4.40E-07 15/48 K.DK[136.11]WSNFDPTGLER[166.11].A "sp|Q5T9A4|ATD3B_HUMAN,sp|Q9NVI7|ATD3A_HUMAN,tr|A0A5K1VW56|A0A5K1VW56_HUMAN,tr|H0Y2W2|H0Y2W2_HUMAN" 4 1581.7542 0.98 69792 18801 3 1581.753727 528.2587 ATPase family AAA domain-containing protein 3B OS=Homo sapiens OX=9606 GN=ATAD3B PE=1 SV=1 4.56 3155.7 - 1.43E+06 - - - -0.325 - 2.975 0.425 - 304.3 1 2 1 -0.0005 13 0 0 0 2.03E+07 2.08E+07 - - - 6.2342 1 221125_WJC_METTL3_EV_vs_WT_F05.18804.18804.3 2.61E-11 20/68 R.VQAHAAAALINFTEDC[160.03]PK.S "sp|O00410|IPO5_HUMAN,tr|H0Y8C6|H0Y8C6_HUMAN" 2 1954.9571 0.7 69795 18804 3 1954.957756 652.6596 Importin-5 OS=Homo sapiens OX=9606 GN=IPO5 PE=1 SV=4 5.32 3156 - 962748 - - - 0.3371 - 3.561 0.651 - 618.9 1 2 0 0.0007 18 0 0 0 1.04E+07 1.48E+07 - - - 8.9604 0.9919 221125_WJC_METTL3_EV_vs_WT_F05.18807.18807.3 2.40E-06 13/48 T.KWELLQQVDTSTR.T sp|P04264|K2C1_HUMAN 1 1602.8366 21.18 69798 18807 3 1602.835054 535.2861 "Keratin, type II cytoskeletal 1 OS=Homo sapiens OX=9606 GN=KRT1 PE=1 SV=6" 6.07 3156.4 - 581727 - - - -0.9458 - 2.574 0.389 - 274.4 1 1 0 -0.0015 13 0 0 0 8.05E+06 3.80E+05 - - - 5.44 1 221125_WJC_METTL3_EV_vs_WT_F05.18808.18808.3 0.00116 Dec-44 K.DHQYQFLEDAVR.N "sp|Q13263|TIF1B_HUMAN,tr|M0R2I3|M0R2I3_HUMAN,tr|M0R3C0|M0R3C0_HUMAN" 3 1519.7056 0.92 69799 18808 3 1519.70717 507.5758 Transcription intermediary factor 1-beta OS=Homo sapiens OX=9606 GN=TRIM28 PE=1 SV=5 4.54 3156.5 - 443477 - - - 1.062 - 2.928 0.544 - 301.6 1 2 0 0.0016 12 0 0 0 3.27E+07 3.54E+07 - - - 7.5825 0.9999 221125_WJC_METTL3_EV_vs_WT_F05.18809.18809.3 8.71E-07 18/56 R.MR[166.11]IESLSSQLSNLQK[136.11].E "sp|P20700|LMNB1_HUMAN,tr|E9PBF6|E9PBF6_HUMAN,tr|A0A0D9SFE5|A0A0D9SFE5_HUMAN" 3 1750.9366 1.11 69800 18809 3 1750.936233 584.6528 Lamin-B1 OS=Homo sapiens OX=9606 GN=LMNB1 PE=1 SV=2 8.5 3156.6 - 437294 - - - -0.2319 - 3.485 0.525 - 502 1 2 1 -0.0004 15 0 0 0 5.53E+06 4.99E+06 - - - 7.6508 1 221125_WJC_METTL3_EV_vs_WT_F05.18810.18810.3 1.18E-08 18/64 R.EENLIPYSPDVQIHAER.F sp|Q8N766|EMC1_HUMAN 1 2008.9854 0.41 69801 18810 3 2008.991728 670.6691 ER membrane protein complex subunit 1 OS=Homo sapiens OX=9606 GN=EMC1 PE=1 SV=1 4.4 3156.7 - 410443 - - - 3.1399 - 3.654 0.576 - 468.9 1 2 0 0.0063 17 0 0 0 8.10E+06 1.96E+07 - - - 8.2337 0.8418 221125_WJC_METTL3_EV_vs_WT_F05.18811.18811.3 1.53 Aug-44 R.QLFHPEQLITGK[136.11].E "sp|Q9NY65|TBA8_HUMAN,sp|Q6PEY2|TBA3E_HUMAN,sp|P0DPH7|TBA3C_HUMAN,sp|Q71U36|TBA1A_HUMAN,sp|P0DPH8|TBA3D_HUMAN,sp|Q9H853|TBA4B_HUMAN,sp|P68366|TBA4A_HUMAN,sp|P68363|TBA1B_HUMAN,sp|Q9BQE3|TBA1C_HUMAN,tr|C9JJQ8|C9JJQ8_HUMAN,tr|F8VS66|F8VS66_HUMAN,tr|F8VWV9|F8VWV9_HUMAN,tr|F8VRZ4|F8VRZ4_HUMAN,tr|F8VVB9|F8VVB9_HUMAN,tr|C9JQ00|C9JQ00_HUMAN,tr|C9JEV8|C9JEV8_HUMAN,tr|A0A7P0TA31|A0A7P0TA31_HUMAN,tr|A0A1W2PQM2|A0A1W2PQM2_HUMAN,tr|F5H5D3|F5H5D3_HUMAN,tr|C9J2C0|C9J2C0_HUMAN,tr|C9K0S6|C9K0S6_HUMAN,tr|C9JDL2|C9JDL2_HUMAN,tr|F8VQQ4|F8VQQ4_HUMAN,tr|F8VX09|F8VX09_HUMAN,tr|A0A7P0T945|A0A7P0T945_HUMAN" 25 1417.7809 0.48 69802 18811 3 1417.779577 473.6009 Tubulin alpha-8 chain OS=Homo sapiens OX=9606 GN=TUBA8 PE=1 SV=1 6.75 3156.9 - 334070 - - - -0.9331 - 1.383 0.065 - 84.7 1 2 0 -0.0013 12 0 0 0 5.77E+06 1.20E+07 - - - 0.1631 1 221125_WJC_METTL3_EV_vs_WT_F05.18812.18812.3 3.98E-11 17/84 K.EAQDAPGLDPQGAADC[160.03]AQGVLR[166.11].Q "sp|P39880|CUX1_HUMAN,tr|A0A2R8Y852|A0A2R8Y852_HUMAN,tr|A0A2R8YDI1|A0A2R8YDI1_HUMAN" 3 2248.0418 1.83 69803 18812 3 2248.035615 750.3545 Homeobox protein cut-like 1 OS=Homo sapiens OX=9606 GN=CUX1 PE=1 SV=3 3.84 3157 - 302100 - - - -2.7419 - 3.18 0.613 - 267.6 1 2 0 -0.0062 22 0 0 0 6.59E+06 3.59E+06 - - - 8.1154 0.9999 221125_WJC_METTL3_EV_vs_WT_F05.18825.18825.3 8.16E-06 15/76 K.EDSAPSKPVVGIIYPPPEVR.N "sp|Q15459|SF3A1_HUMAN,tr|F8WB66|F8WB66_HUMAN" 2 2149.1419 1.24 69814 18825 3 2149.147601 717.3879 Splicing factor 3A subunit 1 OS=Homo sapiens OX=9606 GN=SF3A1 PE=1 SV=1 4.68 3158.6 - 332219 - - - 2.6434 - 2.983 0.538 - 190.6 1 2 0 0.0057 20 0 0 0 1.73E+07 1.39E+07 - - - 7.1881 0.9996 221125_WJC_METTL3_EV_vs_WT_F05.18826.18826.3 0.00645 Aug-68 K.QFSNMGLLSQTEDNPSSK.M "sp|Q9UPQ9|TNR6B_HUMAN,tr|H0Y720|H0Y720_HUMAN" 2 1981.9051 1.47 69815 18826 3 1981.906407 661.6423 Trinucleotide repeat-containing gene 6B protein OS=Homo sapiens OX=9606 GN=TNRC6B PE=1 SV=4 4.37 3158.7 - 289294 - - - 0.6494 - 1.819 0.362 - 80.7 1 2 0 0.0013 18 0 0 0 4.47E+06 3.03E+06 - - - 4.0654 1 221125_WJC_METTL3_EV_vs_WT_F05.18827.18827.3 1.34E-11 16/64 R.HVSIQEAESYAESVGAK.H sp|Q9UL25|RAB21_HUMAN 1 1803.8639 0.52 69816 18827 3 1803.858773 602.2952 Ras-related protein Rab-21 OS=Homo sapiens OX=9606 GN=RAB21 PE=1 SV=3 4.75 3158.9 - 249015 - - - -2.8467 - 3.294 0.671 - 394.6 1 2 0 -0.0051 17 0 0 0 3.47E+06 6.64E+06 - - - 9.0312 0.9995 221125_WJC_METTL3_EV_vs_WT_F05.18828.18828.3 0.00362 Oct-44 K.LNDLEDALQQAK.E sp|P04264|K2C1_HUMAN 1 1356.6885 999 69817 18828 3 1356.685779 453.2368 "Keratin, type II cytoskeletal 1 OS=Homo sapiens OX=9606 GN=KRT1 PE=1 SV=6" 4.03 3159 - 174674 - - - -2.0123 - 1.87 0.354 - 196.3 1 2 0 -0.0027 12 0 0 0 1.92E+06 0.00E+00 - - - 4.221 0.9985 221125_WJC_METTL3_EV_vs_WT_F05.18830.18830.3 1.04E-07 14/56 R.TC[160.03]EEHQLC[160.03]VVAVLPH.L sp|Q15084|PDIA6_HUMAN 1 1790.8444 - 69818 18830 3 1790.844042 597.9554 Protein disulfide-isomerase A6 OS=Homo sapiens OX=9606 GN=PDIA6 PE=1 SV=1 5.21 3159.2 - 343900 - - - -0.1859 - 2.605 0.588 - 217.6 1 1 0 -0.0003 15 0 0 0 - - - - - 7.5938 1 221125_WJC_METTL3_EV_vs_WT_F05.18838.18838.3 3.18E-05 Dec-44 K.DHQYQFLEDAVR[166.11].N "sp|Q13263|TIF1B_HUMAN,tr|M0R2I3|M0R2I3_HUMAN,tr|M0R3C0|M0R3C0_HUMAN" 3 1529.7138 0.92 69824 18838 3 1529.713133 510.9119 Transcription intermediary factor 1-beta OS=Homo sapiens OX=9606 GN=TRIM28 PE=1 SV=5 4.54 3160.2 - 2.13E+06 - - - -0.453 - 2.848 0.495 - 290.5 1 2 0 -0.0007 12 0 0 0 3.27E+07 3.54E+07 - - - 6.9596 1 221125_WJC_METTL3_EV_vs_WT_F05.18840.18840.3 3.23E-10 17/88 K.GVNC[160.03]IDYYSGGDK[136.11]PYLISGADDR[166.11].L "sp|P35606|COPB2_HUMAN,tr|H0Y938|H0Y938_HUMAN,tr|A0A7I2V3G0|A0A7I2V3G0_HUMAN,tr|A0A7I2V258|A0A7I2V258_HUMAN,tr|H0YAC7|H0YAC7_HUMAN,tr|A0A7I2YQF9|A0A7I2YQF9_HUMAN" 6 2552.1608 0.5 69826 18840 3 2552.153147 851.7276 Coatomer subunit beta' OS=Homo sapiens OX=9606 GN=COPB2 PE=1 SV=2 4.14 3160.5 - 628532 - - - -3.0135 - 2.851 0.65 - 178.3 1 2 0 -0.0077 23 0 0 0 3.43E+06 6.91E+06 - - - 8.2425 1 221125_WJC_METTL3_EV_vs_WT_F05.18845.18845.2 6.41E-09 14/36 R.SIQETLGESGSLLPNKLNK.L sp|Q96BP2|CHCH1_HUMAN 1 2027.0899 1.15 69829 18845 2 2027.089678 1014.5522 Coiled-coil-helix-coiled-coil-helix domain-containing protein 1 OS=Homo sapiens OX=9606 GN=CHCHD1 PE=1 SV=1 5.86 3161.1 - 248489 - - - -0.1021 - 2.968 0.603 - 337.4 1 2 1 -0.0002 19 0 0 0 3.55E+07 3.07E+07 - - - 6.1693 0.9984 221125_WJC_METTL3_EV_vs_WT_F05.18846.18846.2 0.000208 Oct-36 R.SIQETLGESGSLLPNK[136.11]LNK[136.11].L sp|Q96BP2|CHCH1_HUMAN 1 2043.1183 1.15 69830 18846 2 2043.115301 1022.5664 Coiled-coil-helix-coiled-coil-helix domain-containing protein 1 OS=Homo sapiens OX=9606 GN=CHCHD1 PE=1 SV=1 5.86 3161.2 - 232424 - - - -1.4605 - 2.279 0.586 - 163.7 1 2 1 -0.003 19 0 0 0 3.55E+07 3.07E+07 - - - 5.3935 1 221125_WJC_METTL3_EV_vs_WT_F05.18848.18848.3 1.44E-08 14/88 K.GVNC[160.03]IDYYSGGDKPYLISGADDR.L "sp|P35606|COPB2_HUMAN,tr|H0Y938|H0Y938_HUMAN,tr|A0A7I2V3G0|A0A7I2V3G0_HUMAN,tr|A0A7I2V258|A0A7I2V258_HUMAN,tr|H0YAC7|H0YAC7_HUMAN,tr|A0A7I2YQF9|A0A7I2YQF9_HUMAN" 6 2534.1384 0.5 69832 18848 3 2534.140457 845.7201 Coatomer subunit beta' OS=Homo sapiens OX=9606 GN=COPB2 PE=1 SV=2 4.14 3161.5 - 421848 - - - 0.8243 - 2.942 0.682 - 183.7 1 2 0 0.0021 23 0 0 0 3.43E+06 6.91E+06 - - - 8.6745 1 221125_WJC_METTL3_EV_vs_WT_F05.18851.18851.3 0.00233 26/76 M.RILSAENIPNLPPGGGLAGK.R "sp|O75688|PPM1B_HUMAN,tr|B8ZZF0|B8ZZF0_HUMAN,tr|A0A3B3IS24|A0A3B3IS24_HUMAN,tr|C9JIR6|C9JIR6_HUMAN" 4 1973.1058 4.05 69834 18851 3 1973.106076 658.7092 Protein phosphatase 1B OS=Homo sapiens OX=9606 GN=PPM1B PE=1 SV=1 8.75 3161.8 - 1.46E+06 - - - 0.1348 - 3.855 0.602 - 681.6 1 1 0 0.0003 20 0 0 0 8.07E+07 1.99E+07 - - - 8.5252 0.9994 221125_WJC_METTL3_EV_vs_WT_F05.18853.18853.3 0.00048 13/72 K.TPAPATTTSHNPLANILSK.V sp|Q5VT52|RPRD2_HUMAN 1 1933.0269 3.35 69836 18853 3 1933.019763 645.3496 Regulation of nuclear pre-mRNA domain-containing protein 2 OS=Homo sapiens OX=9606 GN=RPRD2 PE=1 SV=1 8.44 3162 - 404404 - - - -3.6875 - 2.004 0.448 - 133.1 1 2 0 -0.0071 19 0 0 0 6.68E+07 1.99E+07 - - - 5.2406 1 221125_WJC_METTL3_EV_vs_WT_F05.18857.18857.2 1.65E-06 13/26 K.HTDESLGDC[160.03]SFLNT.C "sp|Q86U44|MTA70_HUMAN,tr|H0YFV6|H0YFV6_HUMAN" 2 1594.657 - 69838 18857 2 1594.649887 798.3358 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 4.02 3162.6 - 1.00E+06 - - - -4.4298 - 2.498 0.611 - 385.6 1 1 0 -0.0071 14 0 0 0 - - - - - 5.849 1 221125_WJC_METTL3_EV_vs_WT_F05.18872.18872.3 1.44E-07 24/92 K.EGTLTQVPLAPPPPGAPPSPAPAR[166.11].F sp|P48634|PRC2A_HUMAN 1 2327.2513 1.64 69850 18872 3 2327.249154 776.7577 Protein PRRC2A OS=Homo sapiens OX=9606 GN=PRRC2A PE=1 SV=3 6.1 3164.3 - 460678 - - - -0.9225 - 3.945 0.465 - 594.2 1 2 0 -0.0021 24 0 0 0 1.24E+08 7.56E+07 - - - 6.9113 1 221125_WJC_METTL3_EV_vs_WT_F05.18883.18883.3 2.96E-12 25/68 K.RPTEIC[160.03]ADPQFIIGGATR.T sp|P17655|CAN2_HUMAN 1 2001.0102 1.19 69856 18883 3 2001.007757 668.0107 Calpain-2 catalytic subunit OS=Homo sapiens OX=9606 GN=CAPN2 PE=1 SV=6 6.06 3165.8 - 841587 - - - -1.2184 - 3.485 0.695 - 770 1 2 0 -0.0024 18 0 0 0 5.23E+07 4.40E+07 - - - 9.3967 1 221125_WJC_METTL3_EV_vs_WT_F05.18884.18884.2 6.93E-09 28-Dec K.HTDESLGDC[160.03]SFLNTC[160.03].F "sp|Q86U44|MTA70_HUMAN,tr|H0YFV6|H0YFV6_HUMAN" 2 1754.6876 - 69857 18884 2 1754.679387 878.3511 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 4.02 3166 - 520395 - - - -4.6806 - 2.901 0.736 - 351.6 1 1 0 -0.0082 15 0 0 0 - - - - - 7.093 0.9926 221125_WJC_METTL3_EV_vs_WT_F05.18888.18888.3 0.00206 15/52 R.K[136.11]HAASDVDLEIESL.L "sp|Q86U44|MTA70_HUMAN,tr|F5H6D8|F5H6D8_HUMAN,tr|H0YFV6|H0YFV6_HUMAN,tr|B4DTN4|B4DTN4_HUMAN" 4 1533.7766 0.02 69859 18888 3 1533.774293 512.2661 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 4.31 3166.4 - 1.27E+06 - - - -1.5054 - 3.049 0.387 - 351.3 1 1 0 -0.0023 14 0 0 0 2.45E+07 1.33E+09 - - - 5.8167 1 221125_WJC_METTL3_EV_vs_WT_F05.18891.18891.2 3.82E-10 15/28 K.QC[160.03]ANLQAAIADAEQR.G "sp|P04259|K2C6B_HUMAN,sp|P02538|K2C6A_HUMAN" 2 1657.7842 999 69862 18891 2 1657.776323 829.8994 "Keratin, type II cytoskeletal 6B OS=Homo sapiens OX=9606 GN=KRT6B PE=1 SV=5" 4.37 3166.8 - 658605 - - - -4.7624 - 3.168 0.651 - 655.4 1 2 0 -0.0079 15 0 0 0 6.57E+08 0.00E+00 - - - 6.6818 1 221125_WJC_METTL3_EV_vs_WT_F05.18897.18897.3 4.67E-11 18/56 K.QC[160.03]ANLQAAIADAEQR.G "sp|P04259|K2C6B_HUMAN,sp|P02538|K2C6A_HUMAN" 2 1657.7842 723.56 69864 18897 3 1657.784162 553.602 "Keratin, type II cytoskeletal 6B OS=Homo sapiens OX=9606 GN=KRT6B PE=1 SV=5" 4.37 3167.5 - 2.34E+06 - - - -0.0338 - 3.736 0.616 - 623 1 2 0 -0.0001 15 0 0 0 6.50E+08 8.99E+05 - - - 8.847 1 221125_WJC_METTL3_EV_vs_WT_F05.18899.18899.2 1.55E-17 20/32 R.AADTDGDGQVNYEEFVR.V sp|P27482|CALL3_HUMAN 1 1884.8126 999 69866 18899 2 1884.81424 943.4136 Calmodulin-like protein 3 OS=Homo sapiens OX=9606 GN=CALML3 PE=1 SV=2 3.77 3167.8 - 1.07E+06 - - - 0.8701 - 4.206 0.8 - 1397.8 1 2 0 0.0016 17 0 0 0 5.41E+07 0.00E+00 - - - 8.481 1 221125_WJC_METTL3_EV_vs_WT_F05.18903.18903.3 4.92E-11 24/72 R.SIQETLGESGSLLPNK[136.11]LNK[136.11].L sp|Q96BP2|CHCH1_HUMAN 1 2043.1183 1.32 69867 18903 3 2043.113603 682.0467 Coiled-coil-helix-coiled-coil-helix domain-containing protein 1 OS=Homo sapiens OX=9606 GN=CHCHD1 PE=1 SV=1 5.86 3168.4 - 2.78E+07 - - - -2.2916 - 3.959 0.691 - 471.6 1 2 1 -0.0047 19 0 0 0 1.66E+09 1.25E+09 - - - 9.6232 0.9943 221125_WJC_METTL3_EV_vs_WT_F05.18911.18911.2 2.83E-07 16/26 R.K[136.11]HAASDVDLEIESL.L "sp|Q86U44|MTA70_HUMAN,tr|F5H6D8|F5H6D8_HUMAN,tr|H0YFV6|H0YFV6_HUMAN,tr|B4DTN4|B4DTN4_HUMAN" 4 1533.7766 0.001 69870 18911 2 1533.775633 767.8956 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 4.31 3169.4 - 2.16E+06 - - - -0.6318 - 2.67 0.538 - 878.5 1 1 0 -0.001 14 0 0 0 0.00E+00 3.82E+08 - - - 5.4788 1 221125_WJC_METTL3_EV_vs_WT_F05.18929.18929.3 6.06E-09 22/68 K.ATGRPEC[160.03]FLTIQEGLASK.F "sp|O00566|MPP10_HUMAN,tr|U3KQ48|U3KQ48_HUMAN" 2 1976.999 1.86 69875 18929 3 1976.994378 660.0069 U3 small nucleolar ribonucleoprotein protein MPP10 OS=Homo sapiens OX=9606 GN=MPHOSPH10 PE=1 SV=2 6.18 3172 - 2.65E+06 - - - -2.3187 - 4.066 0.518 - 827.8 1 2 0 -0.0046 18 0 0 0 7.03E+07 3.77E+07 - - - 7.8067 0.9987 221125_WJC_METTL3_EV_vs_WT_F05.18931.18931.3 9.89E-08 16/56 K.HTDESLGDC[160.03]SFLNTC[160.03].F "sp|Q86U44|MTA70_HUMAN,tr|H0YFV6|H0YFV6_HUMAN" 2 1754.6876 - 69877 18931 3 1754.690034 585.9031 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 4.02 3172.3 - 1.70E+06 - - - 1.3871 - 2.637 0.663 - 264.8 1 1 0 0.0024 15 0 0 0 - - - - - 8.4613 1 221125_WJC_METTL3_EV_vs_WT_F05.18937.18937.3 2.32E-11 27/92 K.EGTLTQVPLAPPPPGAPPSPAPAR.F sp|P48634|PRC2A_HUMAN 1 2317.243 1.62 69881 18937 3 2317.234377 773.4216 Protein PRRC2A OS=Homo sapiens OX=9606 GN=PRRC2A PE=1 SV=3 6.1 3173 - 2.78E+06 - - - -3.7346 - 4.206 0.613 - 657.3 1 2 0 -0.0087 24 0 0 0 1.22E+08 7.56E+07 - - - 8.7084 0.9998 221125_WJC_METTL3_EV_vs_WT_F05.18944.18944.2 0.000352 20-Nov K.WEGLVYAPPGK.E "sp|Q9Y2W1|TR150_HUMAN,tr|A0A3B3ITZ9|A0A3B3ITZ9_HUMAN" 2 1215.6288 4.84 69884 18944 2 1215.628018 608.8217 Thyroid hormone receptor-associated protein 3 OS=Homo sapiens OX=9606 GN=THRAP3 PE=1 SV=2 6 3173.9 - 1.04E+06 - - - -0.6507 - 2.086 0.478 - 338.3 1 2 0 -0.0008 11 0 0 0 2.67E+07 5.51E+06 - - - 4.5603 0.998 221125_WJC_METTL3_EV_vs_WT_F05.18947.18947.3 0.00219 13/80 K.EEPPK[136.11]ELPAAEPVLSPLEGTK[136.11].M "sp|Q9BY77|PDIP3_HUMAN,tr|F6VRR5|F6VRR5_HUMAN" 2 2246.2017 1.45 69886 18947 3 2246.192374 749.7412 Polymerase delta-interacting protein 3 OS=Homo sapiens OX=9606 GN=POLDIP3 PE=1 SV=2 4.33 3174.2 - 3.31E+06 - - - -4.143 - 2.387 0.472 - 159.6 1 2 1 -0.0093 21 0 0 0 2.47E+08 1.71E+08 - - - 5.8856 0.9972 221125_WJC_METTL3_EV_vs_WT_F05.18948.18948.3 0.00198 15/52 R.KHAASDVDLEIESL.L "sp|Q86U44|MTA70_HUMAN,tr|F5H6D8|F5H6D8_HUMAN,tr|H0YFV6|H0YFV6_HUMAN,tr|B4DTN4|B4DTN4_HUMAN" 4 1525.7624 0.02 69887 18948 3 1525.762322 509.5947 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 4.31 3174.3 - 1.10E+06 - - - -0.0524 - 2.835 0.481 - 252.9 1 1 0 -0.0001 14 0 0 0 2.45E+07 1.33E+09 - - - 6.6719 1 221125_WJC_METTL3_EV_vs_WT_F05.18951.18951.3 0.000401 22/64 R.DHAMVPLEEAAQEYQEK.L sp|P19474|RO52_HUMAN 1 1986.8993 2.55 69888 18951 3 1986.894224 663.307 E3 ubiquitin-protein ligase TRIM21 OS=Homo sapiens OX=9606 GN=TRIM21 PE=1 SV=1 4.25 3174.6 - 1.46E+06 - - - -2.5583 - 4.131 0.601 - 709.4 1 2 0 -0.0051 17 0 0 0 6.38E+07 2.50E+07 - - - 8.8228 0.9999 221125_WJC_METTL3_EV_vs_WT_F05.18952.18952.4 3.20E-07 19/96 R.VIEC[160.03]DVVK[136.11]DYAFVHMEK[136.11].E sp|Q96PK6|RBM14_HUMAN 1 2097.0246 1.65 69889 18952 4 2097.022039 525.2634 RNA-binding protein 14 OS=Homo sapiens OX=9606 GN=RBM14 PE=1 SV=2 4.75 3174.7 - 1.44E+06 - - - -1.2136 - 3.279 0.526 - 256.3 1 2 1 -0.0025 17 0 0 0 6.83E+07 4.13E+07 - - - 4.2159 1 221125_WJC_METTL3_EV_vs_WT_F05.18954.18954.3 4.28E-08 22/68 K.ATGR[166.11]PEC[160.03]FLTIQEGLASK[136.11].F "sp|O00566|MPP10_HUMAN,tr|U3KQ48|U3KQ48_HUMAN" 2 1995.0214 1.86 69891 18954 3 1995.016652 666.0144 U3 small nucleolar ribonucleoprotein protein MPP10 OS=Homo sapiens OX=9606 GN=MPHOSPH10 PE=1 SV=2 6.18 3175 - 1.43E+06 - - - -2.396 - 3.753 0.583 - 654.6 1 2 0 -0.0048 18 0 0 0 7.03E+07 3.77E+07 - - - 8.3318 1 221125_WJC_METTL3_EV_vs_WT_F05.18958.18958.4 3.31E-09 21/102 R.TLSDYNIQKESTLHLVLR.L "sp|P62979|RS27A_HUMAN,sp|P0CG48|UBC_HUMAN,sp|P0CG48|UBC_HUMAN,sp|P0CG48|UBC_HUMAN,sp|P0CG48|UBC_HUMAN,sp|P0CG48|UBC_HUMAN,sp|P0CG48|UBC_HUMAN,sp|P0CG48|UBC_HUMAN,sp|P0CG48|UBC_HUMAN,sp|P0CG48|UBC_HUMAN,sp|P0CG47|UBB_HUMAN,sp|P0CG47|UBB_HUMAN,sp|P0CG47|UBB_HUMAN,sp|P62987|RL40_HUMAN,tr|F5H388|F5H388_HUMAN,tr|F5GYU3|F5GYU3_HUMAN,tr|B4DV12|B4DV12_HUMAN,tr|Q5PY61|Q5PY61_HUMAN,tr|Q5PY61|Q5PY61_HUMAN,tr|Q5PY61|Q5PY61_HUMAN,tr|F5H2Z3|F5H2Z3_HUMAN,tr|M0R2S1|M0R2S1_HUMAN,tr|J3QS39|J3QS39_HUMAN,tr|J3QTR3|J3QTR3_HUMAN,tr|Q96C32|Q96C32_HUMAN,tr|Q96C32|Q96C32_HUMAN,tr|Q96C32|Q96C32_HUMAN,tr|F5H747|F5H747_HUMAN,tr|F5H747|F5H747_HUMAN,tr|F5GXK7|F5GXK7_HUMAN,tr|F5GXK7|F5GXK7_HUMAN,tr|M0R1M6|M0R1M6_HUMAN,tr|F5H6Q2|F5H6Q2_HUMAN,tr|J3QKN0|J3QKN0_HUMAN,tr|J3QKN0|J3QKN0_HUMAN,tr|F5H265|F5H265_HUMAN,tr|A0A2R8Y422|A0A2R8Y422_HUMAN" 37 2129.1481 0.59 69893 18958 4 2129.148939 533.2943 Ubiquitin-40S ribosomal protein S27a OS=Homo sapiens OX=9606 GN=RPS27A PE=1 SV=2 6.42 3175.6 - 1.00E+06 - - - 0.4091 - 3.305 0.625 - 212.4 1 2 1 0.0009 18 0 0 0 9.13E+06 1.55E+07 - - - 5.0753 0.9998 221125_WJC_METTL3_EV_vs_WT_F05.18960.18960.3 1.96E-07 16/72 K.TPAPATTTSHNPLANILSK[136.11].V sp|Q5VT52|RPRD2_HUMAN 1 1941.0411 3.4 69895 18960 3 1941.033317 648.021 Regulation of nuclear pre-mRNA domain-containing protein 2 OS=Homo sapiens OX=9606 GN=RPRD2 PE=1 SV=1 8.44 3175.8 - 850616 - - - -4.0051 - 2.873 0.504 - 329.6 1 2 0 -0.0078 19 0 0 0 6.71E+07 1.97E+07 - - - 6.7498 1 221125_WJC_METTL3_EV_vs_WT_F05.18963.18963.3 8.92E-10 20/72 R.FSHLTSLPQQLPSQQLMSK.D "sp|Q6PKG0|LARP1_HUMAN,tr|A0A0B4J210|A0A0B4J210_HUMAN,tr|H0YC73|H0YC73_HUMAN,tr|E5RH50|E5RH50_HUMAN" 4 2169.1252 1.26 69896 18963 3 2169.123589 724.049 La-related protein 1 OS=Homo sapiens OX=9606 GN=LARP1 PE=1 SV=2 8.76 3176.2 - 1.48E+06 - - - -0.7538 - 3.643 0.567 - 377.8 1 2 0 -0.0016 19 0 0 0 1.53E+07 1.22E+07 - - - 8.0372 1 221125_WJC_METTL3_EV_vs_WT_F05.18965.18965.3 1.10E-08 22/60 K.RGFGFVTFDDHDPVDK.L "sp|P22626|ROA2_HUMAN,tr|A0A7I2V4N0|A0A7I2V4N0_HUMAN,tr|A0A024RA28|A0A024RA28_HUMAN,tr|A0A7I2V4N1|A0A7I2V4N1_HUMAN,tr|A0A7I2V4I6|A0A7I2V4I6_HUMAN,tr|A0A087WUI2|A0A087WUI2_HUMAN,tr|A0A7I2V4S4|A0A7I2V4S4_HUMAN,tr|A0A7I2V323|A0A7I2V323_HUMAN,tr|A0A7I2V3P1|A0A7I2V3P1_HUMAN,tr|A0A7I2V3P7|A0A7I2V3P7_HUMAN" 10 1850.8588 0.05 69898 18965 3 1850.851146 617.9602 Heterogeneous nuclear ribonucleoproteins A2\B1 OS=Homo sapiens OX=9606 GN=HNRNPA2B1 PE=1 SV=2 4.56 3176.4 - 1.62E+06 - - - -4.1154 - 3.447 0.636 - 317 1 2 0 -0.0076 16 0 0 0 1.04E+08 2.24E+09 - - - 8.8039 1 221125_WJC_METTL3_EV_vs_WT_F05.18966.18966.3 1.68E-07 19/72 R.FSHLTSLPQQLPSQQLMSK[136.11].D "sp|Q6PKG0|LARP1_HUMAN,tr|A0A0B4J210|A0A0B4J210_HUMAN,tr|H0YC73|H0YC73_HUMAN,tr|E5RH50|E5RH50_HUMAN" 4 2177.1394 1.26 69899 18966 3 2177.136079 726.7204 La-related protein 1 OS=Homo sapiens OX=9606 GN=LARP1 PE=1 SV=2 8.76 3176.5 - 1.53E+06 - - - -1.5364 - 3.544 0.555 - 355.2 1 2 0 -0.0033 19 0 0 0 1.53E+07 1.22E+07 - - - 7.8353 0.9999 221125_WJC_METTL3_EV_vs_WT_F05.18967.18967.4 4.37E-05 17/90 K.R[166.11]GFGFVTFDDHDPVDK[136.11].L "sp|P22626|ROA2_HUMAN,tr|A0A7I2V4N0|A0A7I2V4N0_HUMAN,tr|A0A024RA28|A0A024RA28_HUMAN,tr|A0A7I2V4N1|A0A7I2V4N1_HUMAN,tr|A0A7I2V4I6|A0A7I2V4I6_HUMAN,tr|A0A087WUI2|A0A087WUI2_HUMAN,tr|A0A7I2V4S4|A0A7I2V4S4_HUMAN,tr|A0A7I2V323|A0A7I2V323_HUMAN,tr|A0A7I2V3P1|A0A7I2V3P1_HUMAN,tr|A0A7I2V3P7|A0A7I2V3P7_HUMAN" 10 1868.8812 1.16 69900 18967 4 1868.875059 468.2276 Heterogeneous nuclear ribonucleoproteins A2\B1 OS=Homo sapiens OX=9606 GN=HNRNPA2B1 PE=1 SV=2 4.56 3176.6 - 1.31E+06 - - - -3.3036 - 2.781 0.555 - 234.6 1 2 0 -0.0062 16 0 0 0 2.29E+07 1.97E+07 - - - 4.4153 0.9999 221125_WJC_METTL3_EV_vs_WT_F05.18968.18968.4 0.00656 15/78 K.IDIYHYELDIKPEK.C "sp|Q9UKV8|AGO2_HUMAN,tr|E5RJY2|E5RJY2_HUMAN" 2 1774.9142 1.65 69901 18968 4 1774.911615 444.7358 Protein argonaute-2 OS=Homo sapiens OX=9606 GN=AGO2 PE=1 SV=3 4.75 3176.8 - 1.30E+06 - - - -1.4294 - 2.439 0.432 - 112.6 1 2 0 -0.0025 14 0 0 0 1.38E+07 8.36E+06 - - - 3.3099 0.9999 221125_WJC_METTL3_EV_vs_WT_F05.18972.18972.4 1.39E-09 20/102 R.TLSDYNIQK[136.11]ESTLHLVLR[166.11].L "sp|P62979|RS27A_HUMAN,sp|P0CG48|UBC_HUMAN,sp|P0CG48|UBC_HUMAN,sp|P0CG48|UBC_HUMAN,sp|P0CG48|UBC_HUMAN,sp|P0CG48|UBC_HUMAN,sp|P0CG48|UBC_HUMAN,sp|P0CG48|UBC_HUMAN,sp|P0CG48|UBC_HUMAN,sp|P0CG48|UBC_HUMAN,sp|P0CG47|UBB_HUMAN,sp|P0CG47|UBB_HUMAN,sp|P0CG47|UBB_HUMAN,sp|P62987|RL40_HUMAN,tr|F5H388|F5H388_HUMAN,tr|F5GYU3|F5GYU3_HUMAN,tr|B4DV12|B4DV12_HUMAN,tr|Q5PY61|Q5PY61_HUMAN,tr|Q5PY61|Q5PY61_HUMAN,tr|Q5PY61|Q5PY61_HUMAN,tr|F5H2Z3|F5H2Z3_HUMAN,tr|M0R2S1|M0R2S1_HUMAN,tr|J3QS39|J3QS39_HUMAN,tr|J3QTR3|J3QTR3_HUMAN,tr|Q96C32|Q96C32_HUMAN,tr|Q96C32|Q96C32_HUMAN,tr|Q96C32|Q96C32_HUMAN,tr|F5H747|F5H747_HUMAN,tr|F5H747|F5H747_HUMAN,tr|F5GXK7|F5GXK7_HUMAN,tr|F5GXK7|F5GXK7_HUMAN,tr|M0R1M6|M0R1M6_HUMAN,tr|F5H6Q2|F5H6Q2_HUMAN,tr|J3QKN0|J3QKN0_HUMAN,tr|J3QKN0|J3QKN0_HUMAN,tr|F5H265|F5H265_HUMAN,tr|A0A2R8Y422|A0A2R8Y422_HUMAN" 37 2147.1705 0.57 69903 18972 4 2147.170105 537.7999 Ubiquitin-40S ribosomal protein S27a OS=Homo sapiens OX=9606 GN=RPS27A PE=1 SV=2 6.42 3177.3 - 919744 - - - -0.2017 - 3.087 0.577 - 195.4 1 2 1 -0.0004 18 0 0 0 8.84E+06 1.55E+07 - - - 4.6342 1 221125_WJC_METTL3_EV_vs_WT_F05.18975.18975.3 1.12E-12 22/84 K.VGNPFELDTQQGPQVDKEQFER.V sp|P30837|AL1B1_HUMAN 1 2560.2194 7.46 69906 18975 3 2560.211875 854.4137 "Aldehyde dehydrogenase X, mitochondrial OS=Homo sapiens OX=9606 GN=ALDH1B1 PE=1 SV=3" 4.18 3177.6 - 746409 - - - -2.9372 - 4.4 0.679 - 699.1 1 2 1 -0.0075 22 0 0 0 1.01E+07 1.35E+06 - - - 9.6207 0.9998 221125_WJC_METTL3_EV_vs_WT_F05.18976.18976.3 2.50E-09 13/64 R.VIEC[160.03]DVVKDYAFVHMEK.E sp|Q96PK6|RBM14_HUMAN 1 2080.9962 4.58 69907 18976 3 2081.002463 694.6727 RNA-binding protein 14 OS=Homo sapiens OX=9606 GN=RBM14 PE=1 SV=2 4.75 3177.7 - 686202 - - - 3.0173 - 2.834 0.591 - 145 1 2 1 0.0063 17 0 0 0 6.36E+07 1.39E+07 - - - 7.7589 1 221125_WJC_METTL3_EV_vs_WT_F05.18981.18981.2 2.46E-08 13/26 K.HSNSNSVDDTIVAL.N "sp|P52948|NUP98_HUMAN,tr|A0A3B3ITD8|A0A3B3ITD8_HUMAN" 2 1470.6951 - 69910 18981 2 1470.693755 736.3548 Nuclear pore complex protein Nup98-Nup96 OS=Homo sapiens OX=9606 GN=NUP98 PE=1 SV=4 4.2 3178.4 - 996049 - - - -0.8812 - 2.39 0.62 - 542.1 1 1 0 -0.0013 14 0 0 0 - - - - - 5.8064 1 221125_WJC_METTL3_EV_vs_WT_F05.18982.18982.3 3.50E-15 26/72 K.SIEEQLGTEIKPIPSNIDK.S sp|P26196|DDX6_HUMAN 1 2110.1158 1.13 69911 18982 3 2110.113771 704.3792 Probable ATP-dependent RNA helicase DDX6 OS=Homo sapiens OX=9606 GN=DDX6 PE=1 SV=2 4.41 3178.5 - 1.37E+06 - - - -0.945 - 4.009 0.688 - 503.6 1 2 0 -0.002 19 0 0 0 1.30E+08 1.15E+08 - - - 9.6213 1 221125_WJC_METTL3_EV_vs_WT_F05.18983.18983.3 1.35E-12 29/128 R.AGVLGGPATPASGPGPASAEPAVTEPGLGPDPK.D sp|Q9NPF5|DMAP1_HUMAN 1 2921.4771 1.77 69912 18983 3 2921.474821 974.833 DNA methyltransferase 1-associated protein 1 OS=Homo sapiens OX=9606 GN=DMAP1 PE=1 SV=1 4.14 3178.6 - 1.13E+06 - - - -0.7688 - 4.37 0.643 - 562 1 2 0 -0.0022 33 0 0 0 2.85E+07 1.61E+07 - - - 9.1011 0.9998 221125_WJC_METTL3_EV_vs_WT_F05.18985.18985.4 2.12E-05 17/84 K.SK[136.11]NILFVITK[136.11]PDVYK[136.11].S "sp|E9PAV3|NACAM_HUMAN,sp|Q9BZK3|NACP4_HUMAN,sp|Q13765|NACA_HUMAN,tr|A0A7I2V473|A0A7I2V473_HUMAN,tr|F8VZJ2|F8VZJ2_HUMAN,tr|F8VNW4|F8VNW4_HUMAN,tr|A0A7I2V2K5|A0A7I2V2K5_HUMAN,tr|F8W0W4|F8W0W4_HUMAN,tr|H0YHX9|H0YHX9_HUMAN,tr|F8VZ58|F8VZ58_HUMAN" 10 1788.0612 0.32 69914 18985 4 1788.059493 448.0226 "Nascent polypeptide-associated complex subunit alpha, muscle-specific form OS=Homo sapiens OX=9606 GN=NACA PE=1 SV=1" 9.52 3178.9 - 523410 - - - -0.9312 - 2.579 0.491 - 258.6 1 2 1 -0.0017 15 0 0 0 2.17E+06 6.75E+06 - - - 3.8382 0.9999 221125_WJC_METTL3_EV_vs_WT_F05.18986.18986.3 0.000488 15/56 K.SK[136.11]NILFVITK[136.11]PDVYK[136.11].S "sp|E9PAV3|NACAM_HUMAN,sp|Q9BZK3|NACP4_HUMAN,sp|Q13765|NACA_HUMAN,tr|A0A7I2V473|A0A7I2V473_HUMAN,tr|F8VZJ2|F8VZJ2_HUMAN,tr|F8VNW4|F8VNW4_HUMAN,tr|A0A7I2V2K5|A0A7I2V2K5_HUMAN,tr|F8W0W4|F8W0W4_HUMAN,tr|H0YHX9|H0YHX9_HUMAN,tr|F8VZ58|F8VZ58_HUMAN" 10 1788.0612 0.37 69915 18986 3 1788.06067 597.0277 "Nascent polypeptide-associated complex subunit alpha, muscle-specific form OS=Homo sapiens OX=9606 GN=NACA PE=1 SV=1" 9.52 3179 - 458388 - - - -0.2729 - 2.617 0.482 - 192 1 2 1 -0.0005 15 0 0 0 1.56E+06 4.15E+06 - - - 6.424 1 221125_WJC_METTL3_EV_vs_WT_F05.18989.18989.2 3.09E-12 17/30 R.NQGDEEGTEIDTLQFR[166.11].L "sp|O15160|RPAC1_HUMAN,tr|D6RDJ3|D6RDJ3_HUMAN,tr|A0A2R8YEZ4|A0A2R8YEZ4_HUMAN,tr|E7EQB9|E7EQB9_HUMAN,tr|A0A2R8Y5D3|A0A2R8Y5D3_HUMAN,tr|A0A2R8YEY5|A0A2R8YEY5_HUMAN" 6 1860.8365 0.17 69918 18989 2 1860.832585 931.4255 DNA-directed RNA polymerases I and III subunit RPAC1 OS=Homo sapiens OX=9606 GN=POLR1C PE=1 SV=1 3.83 3179.4 - 350658 - - - -2.1146 - 3.37 0.645 - 1228.3 1 2 0 -0.0039 16 0 0 0 2.77E+06 1.64E+07 - - - 6.7907 0.9999 221125_WJC_METTL3_EV_vs_WT_F05.18992.18992.3 9.24E-07 16/56 R.SC[160.03]KDETFLLQAPLQR.R "sp|O00268|TAF4_HUMAN,tr|V9GY14|V9GY14_HUMAN,tr|A0A0G2JRY5|A0A0G2JRY5_HUMAN" 3 1804.9142 1.52 69919 18992 3 1804.913769 602.6453 Transcription initiation factor TFIID subunit 4 OS=Homo sapiens OX=9606 GN=TAF4 PE=1 SV=2 5.79 3179.8 - 1.77E+06 - - - -0.2216 - 2.923 0.575 - 376.3 1 2 1 -0.0004 15 0 0 0 2.38E+07 1.56E+07 - - - 7.7494 0.9999 221125_WJC_METTL3_EV_vs_WT_F05.18994.18994.3 6.68E-07 17/56 R.SC[160.03]K[136.11]DETFLLQAPLQR[166.11].R "sp|O00268|TAF4_HUMAN,tr|V9GY14|V9GY14_HUMAN,tr|A0A0G2JRY5|A0A0G2JRY5_HUMAN" 3 1822.9366 1.52 69921 18994 3 1822.938375 608.6528 Transcription initiation factor TFIID subunit 4 OS=Homo sapiens OX=9606 GN=TAF4 PE=1 SV=2 5.79 3179.9 - 1.47E+06 - - - 0.9523 - 2.678 0.534 - 424.6 1 2 1 0.0017 15 0 0 0 2.38E+07 1.56E+07 - - - 7.0635 0.9984 221125_WJC_METTL3_EV_vs_WT_F05.18996.18996.3 6.15E-06 17/44 S.HNLQSIFNIGSR[166.11].G "sp|P43243|MATR3_HUMAN,tr|A8MXP9|A8MXP9_HUMAN,tr|D6R991|D6R991_HUMAN,tr|D6REK4|D6REK4_HUMAN,tr|A0A0R4J2E8|A0A0R4J2E8_HUMAN,tr|D6RCM3|D6RCM3_HUMAN,tr|D6R8Z5|D6R8Z5_HUMAN,tr|D6REM6|D6REM6_HUMAN" 8 1394.7294 1.26 69923 18996 3 1394.728884 465.9171 Matrin-3 OS=Homo sapiens OX=9606 GN=MATR3 PE=1 SV=2 9.76 3180.2 - 903652 - - - -0.3822 - 2.958 0.537 - 431.9 1 1 0 -0.0005 12 0 0 0 1.07E+07 8.51E+06 - - - 7.533 1 221125_WJC_METTL3_EV_vs_WT_F05.18998.18998.3 2.93E-07 Nov-60 R.NQGDEEGTEIDTLQFR[166.11].L "sp|O15160|RPAC1_HUMAN,tr|D6RDJ3|D6RDJ3_HUMAN,tr|A0A2R8YEZ4|A0A2R8YEZ4_HUMAN,tr|E7EQB9|E7EQB9_HUMAN,tr|A0A2R8Y5D3|A0A2R8Y5D3_HUMAN,tr|A0A2R8YEY5|A0A2R8YEY5_HUMAN" 6 1860.8365 0.08 69925 18998 3 1860.834636 621.2861 DNA-directed RNA polymerases I and III subunit RPAC1 OS=Homo sapiens OX=9606 GN=POLR1C PE=1 SV=1 3.83 3180.5 - 421970 - - - -1.0124 - 2.341 0.582 - 167.8 1 2 0 -0.0019 16 0 0 0 6.21E+05 7.87E+06 - - - 7.2107 0.9999 221125_WJC_METTL3_EV_vs_WT_F05.18999.18999.3 7.48E-08 13/56 K.DIHLDLPSNNNLVSK.D "sp|P18583|SON_HUMAN,tr|H7C1M2|H7C1M2_HUMAN" 2 1677.8686 0.98 69926 18999 3 1677.874488 560.2968 Protein SON OS=Homo sapiens OX=9606 GN=SON PE=1 SV=4 5.21 3180.6 - 384114 - - - 3.5098 - 2.72 0.518 - 251 1 2 0 0.0059 15 0 0 0 1.27E+07 1.29E+07 - - - 6.9246 1 221125_WJC_METTL3_EV_vs_WT_F05.19000.19000.3 5.73E-05 Nov-48 R.NILSVVGTDALKK.T sp|O43172|PRP4_HUMAN 1 1356.7977 3.1 69927 19000 3 1356.797064 453.2732 U4\U6 small nuclear ribonucleoprotein Prp4 OS=Homo sapiens OX=9606 GN=PRPF4 PE=1 SV=2 8.59 3180.7 - 374719 - - - -0.4437 - 2.513 0.449 - 120.7 1 2 0 -0.0006 13 0 0 0 2.66E+06 8.57E+05 - - - 6.0441 1 221125_WJC_METTL3_EV_vs_WT_F05.19001.19001.2 7.02E-11 15/28 K.EAESC[160.03]DC[160.03]LQGFQLTH.S "sp|P04350|TBB4A_HUMAN,sp|A6NNZ2|TBB8B_HUMAN,sp|P07437|TBB5_HUMAN,sp|P68371|TBB4B_HUMAN,sp|Q3ZCM7|TBB8_HUMAN,tr|Q5ST81|Q5ST81_HUMAN,tr|Q5JP53|Q5JP53_HUMAN,tr|M0R042|M0R042_HUMAN,tr|A0A075B736|A0A075B736_HUMAN,tr|M0R1I1|M0R1I1_HUMAN,tr|Q5SQY0|Q5SQY0_HUMAN" 11 1793.7349 - 69928 19001 2 1793.731264 897.8747 Tubulin beta-4A chain OS=Homo sapiens OX=9606 GN=TUBB4A PE=1 SV=2 4.13 3180.9 - 347430 - - - -2.0181 - 3.157 0.74 - 840.2 1 1 0 -0.0036 15 0 0 0 - - - - - 7.3319 0.9999 221125_WJC_METTL3_EV_vs_WT_F05.19002.19002.3 0.00248 15/52 R.YQVELENLKDEYVR.T "sp|P82094|TMF1_HUMAN,tr|A0A2R8Y7M0|A0A2R8Y7M0_HUMAN" 2 1796.8945 1.09 69929 19002 3 1796.894975 599.9721 TATA element modulatory factor OS=Homo sapiens OX=9606 GN=TMF1 PE=1 SV=2 4.41 3181 - 308592 - - - 0.276 - 3.073 0.44 - 192.7 1 2 1 0.0005 14 0 0 0 1.58E+06 1.44E+06 - - - 6.4289 1 221125_WJC_METTL3_EV_vs_WT_F05.19003.19003.2 5.11E-13 16/34 K.SGDWVC[160.03]PNPSC[160.03]GNMNFAR.R "sp|Q92804|RBP56_HUMAN,tr|A0A075B7F4|A0A075B7F4_HUMAN,tr|A0A075B7D9|A0A075B7D9_HUMAN" 3 2067.8349 1.3 69930 19003 2 2067.835667 1034.9248 TATA-binding protein-associated factor 2N OS=Homo sapiens OX=9606 GN=TAF15 PE=1 SV=1 5.55 3181.1 - 300590 - - - 0.3467 - 3.272 0.805 - 594.3 1 2 0 0.0007 18 0 0 0 3.48E+06 2.67E+06 - - - 7.9009 0.9998 221125_WJC_METTL3_EV_vs_WT_F05.19004.19004.4 8.51E-08 16/192 R.AGVLGGPATPASGPGPASAEPAVTEPGLGPDPK.D sp|Q9NPF5|DMAP1_HUMAN 1 2921.4771 1.67 69931 19004 4 2921.4837 731.3765 DNA methyltransferase 1-associated protein 1 OS=Homo sapiens OX=9606 GN=DMAP1 PE=1 SV=1 4.14 3181.2 - 299446 - - - 2.2704 - 2.949 0.427 - 90.5 1 2 0 0.0066 33 0 0 0 3.20E+06 1.91E+06 - - - 3.2652 0.9976 221125_WJC_METTL3_EV_vs_WT_F05.19009.19009.3 0.000233 18/44 S.HNLQSIFNIGSR.G "sp|P43243|MATR3_HUMAN,tr|A8MXP9|A8MXP9_HUMAN,tr|D6R991|D6R991_HUMAN,tr|D6REK4|D6REK4_HUMAN,tr|A0A0R4J2E8|A0A0R4J2E8_HUMAN,tr|D6RCM3|D6RCM3_HUMAN,tr|D6R8Z5|D6R8Z5_HUMAN,tr|D6REM6|D6REM6_HUMAN" 8 1384.7211 1.24 69934 19009 3 1384.720704 462.581 Matrin-3 OS=Homo sapiens OX=9606 GN=MATR3 PE=1 SV=2 9.76 3181.9 - 1.32E+06 - - - -0.3199 - 2.958 0.478 - 574.6 1 1 0 -0.0004 12 0 0 0 1.05E+07 8.51E+06 - - - 6.8752 0.9916 221125_WJC_METTL3_EV_vs_WT_F05.19010.19010.3 0.000254 Dec-56 K.EAESC[160.03]DC[160.03]LQGFQLTH.S "sp|P04350|TBB4A_HUMAN,sp|A6NNZ2|TBB8B_HUMAN,sp|P07437|TBB5_HUMAN,sp|P68371|TBB4B_HUMAN,sp|Q3ZCM7|TBB8_HUMAN,tr|Q5ST81|Q5ST81_HUMAN,tr|Q5JP53|Q5JP53_HUMAN,tr|M0R042|M0R042_HUMAN,tr|A0A075B736|A0A075B736_HUMAN,tr|M0R1I1|M0R1I1_HUMAN,tr|Q5SQY0|Q5SQY0_HUMAN" 11 1793.7349 - 69935 19010 3 1793.733086 598.9189 Tubulin beta-4A chain OS=Homo sapiens OX=9606 GN=TUBB4A PE=1 SV=2 4.13 3182.1 - 648418 - - - -1.0024 - 1.905 0.465 - 215.2 1 1 0 -0.0018 15 0 0 0 - - - - - 5.4055 1 221125_WJC_METTL3_EV_vs_WT_F05.19011.19011.3 7.77E-14 28/128 R.AGVLGGPATPASGPGPASAEPAVTEPGLGPDPK[136.11].D sp|Q9NPF5|DMAP1_HUMAN 1 2929.4913 1.77 69936 19011 3 2929.489543 977.5044 DNA methyltransferase 1-associated protein 1 OS=Homo sapiens OX=9606 GN=DMAP1 PE=1 SV=1 4.14 3182.2 - 1.75E+06 - - - -0.5885 - 4.346 0.594 - 473.8 1 2 0 -0.0017 33 0 0 0 2.85E+07 1.61E+07 - - - 8.5423 1 221125_WJC_METTL3_EV_vs_WT_F05.19015.19015.3 2.08E-07 20/80 R.QHLGATGGPGAQLGASFLQAR.H "sp|Q9NWW5|CLN6_HUMAN,tr|H3BUT1|H3BUT1_HUMAN,tr|A0A1B0GTV3|A0A1B0GTV3_HUMAN,tr|H3BNF1|H3BNF1_HUMAN,tr|A0A1B0GW73|A0A1B0GW73_HUMAN,tr|A0A1B0GUD2|A0A1B0GUD2_HUMAN,tr|H3BUV4|H3BUV4_HUMAN,tr|A0A0S2Z5D0|A0A0S2Z5D0_HUMAN,tr|A0A1B0GTU6|A0A1B0GTU6_HUMAN,tr|H3BTY4|H3BTY4_HUMAN,tr|H3BRN7|H3BRN7_HUMAN" 11 2036.0552 1.67 69940 19015 3 2036.061139 679.6923 Ceroid-lipofuscinosis neuronal protein 6 OS=Homo sapiens OX=9606 GN=CLN6 PE=1 SV=1 9.76 3182.7 - 548678 - - - 2.9312 - 4.091 0.575 - 358.8 1 2 0 0.006 21 0 0 0 4.93E+06 2.95E+06 - - - 8.3265 1 221125_WJC_METTL3_EV_vs_WT_F05.19016.19016.3 3.63E-07 20/68 K.SGDWVC[160.03]PNPSC[160.03]GNMNFAR[166.11].R "sp|Q92804|RBP56_HUMAN,tr|A0A075B7F4|A0A075B7F4_HUMAN,tr|A0A075B7D9|A0A075B7D9_HUMAN" 3 2077.8432 1.52 69941 19016 3 2078.844389 693.6217 TATA-binding protein-associated factor 2N OS=Homo sapiens OX=9606 GN=TAF15 PE=1 SV=1 5.55 3182.8 - 534467 - - - 481.8309 - 3.126 0.714 - 484.9 1 2 0 1.0012 18 0 0 0 4.61E+06 3.04E+06 - - - 9.0612 0.9999 221125_WJC_METTL3_EV_vs_WT_F05.19018.19018.3 8.37E-06 16/52 R.AGK[136.11]LDPHLVLDQLR[166.11].C "sp|P35580|MYH10_HUMAN,sp|P35579|MYH9_HUMAN" 2 1591.9165 0.88 69943 19018 3 1591.917134 531.6461 Myosin-10 OS=Homo sapiens OX=9606 GN=MYH10 PE=1 SV=3 6.79 3183.1 - 475596 - - - 0.4008 - 3.001 0.443 - 380.7 1 2 1 0.0006 14 0 0 0 4.17E+06 4.71E+06 - - - 6.3993 0.9996 221125_WJC_METTL3_EV_vs_WT_F05.19020.19020.4 3.54E-05 15/78 R.AGK[136.11]LDPHLVLDQLR[166.11].C "sp|P35580|MYH10_HUMAN,sp|P35579|MYH9_HUMAN" 2 1591.9165 0.91 69945 19020 4 1591.915159 398.9864 Myosin-10 OS=Homo sapiens OX=9606 GN=MYH10 PE=1 SV=3 6.79 3183.4 - 442020 - - - -0.8399 - 2.451 0.411 - 275.6 1 2 1 -0.0013 14 0 0 0 3.01E+06 3.31E+06 - - - 3.1292 0.999 221125_WJC_METTL3_EV_vs_WT_F05.19021.19021.3 0.0554 Nov-56 K.GGQTHLGLPVFNTVK.E "sp|P53597|SUCA_HUMAN,tr|A0A494C0D1|A0A494C0D1_HUMAN" 2 1566.8518 5.84 69946 19021 3 1566.852929 523.2912 "Succinate--CoA ligase [ADP\GDP-forming] subunit alpha, mitochondrial OS=Homo sapiens OX=9606 GN=SUCLG1 PE=1 SV=4" 8.76 3183.5 - 440093 - - - 0.7033 - 2.002 0.267 - 80.7 1 2 0 0.0011 15 0 0 0 4.65E+06 7.97E+05 - - - 3.3278 1 221125_WJC_METTL3_EV_vs_WT_F05.19024.19024.2 2.31E-09 16/30 R.NQGDEEGTEIDTLQFR.L "sp|O15160|RPAC1_HUMAN,tr|D6RDJ3|D6RDJ3_HUMAN,tr|A0A2R8YEZ4|A0A2R8YEZ4_HUMAN,tr|E7EQB9|E7EQB9_HUMAN,tr|A0A2R8Y5D3|A0A2R8Y5D3_HUMAN,tr|A0A2R8YEY5|A0A2R8YEY5_HUMAN" 6 1850.8283 0.17 69949 19024 2 1850.828485 926.4214 DNA-directed RNA polymerases I and III subunit RPAC1 OS=Homo sapiens OX=9606 GN=POLR1C PE=1 SV=1 3.83 3183.9 - 364322 - - - 0.127 - 3.443 0.666 - 892.3 1 2 0 0.0002 16 0 0 0 2.77E+06 1.64E+07 - - - 6.9996 0.9997 221125_WJC_METTL3_EV_vs_WT_F05.19025.19025.4 0.00027 15/78 R.AGKLDPHLVLDQLR.C "sp|P35580|MYH10_HUMAN,sp|P35579|MYH9_HUMAN" 2 1573.894 0.91 69950 19025 4 1573.891533 394.4808 Myosin-10 OS=Homo sapiens OX=9606 GN=MYH10 PE=1 SV=3 6.79 3184 - 349796 - - - -1.584 - 2.911 0.432 - 267.6 1 2 1 -0.0025 14 0 0 0 3.01E+06 3.31E+06 - - - 3.3743 1 221125_WJC_METTL3_EV_vs_WT_F05.19026.19026.3 2.12E-09 18/48 R.KAHQLWLSVEALK.Y "sp|Q16891|MIC60_HUMAN,tr|B9A067|B9A067_HUMAN,tr|C9J406|C9J406_HUMAN,tr|H7C463|H7C463_HUMAN" 4 1521.8667 1.71 69951 19026 3 1521.869169 508.2962 MICOS complex subunit MIC60 OS=Homo sapiens OX=9606 GN=IMMT PE=1 SV=1 8.6 3184.1 - 349148 - - - 1.5908 - 3.16 0.524 - 503.8 1 2 0 0.0024 13 0 0 0 2.18E+07 1.28E+07 - - - 7.5009 0.9998 221125_WJC_METTL3_EV_vs_WT_F05.19028.19028.3 0.00334 Nov-84 R.VVEPSQPESGAQAC[160.03]WPAPSFQR.Y sp|P0C7T5|ATX1L_HUMAN 1 2427.1277 3.05 69953 19028 3 2427.130674 810.0499 Ataxin-1-like OS=Homo sapiens OX=9606 GN=ATXN1L PE=1 SV=1 4.53 3184.4 - 259153 - - - 1.2072 - 1.992 0.403 - 76.8 1 2 0 0.0029 22 0 0 0 1.27E+06 4.14E+05 - - - 4.6661 0.9999 221125_WJC_METTL3_EV_vs_WT_F05.19032.19032.3 0.0003 Nov-56 K.DIHLDLPSNNNLVSK[136.11].D "sp|P18583|SON_HUMAN,tr|H7C1M2|H7C1M2_HUMAN" 2 1685.8828 0.99 69956 19032 3 1685.883019 562.9682 Protein SON OS=Homo sapiens OX=9606 GN=SON PE=1 SV=4 5.21 3184.8 - 1.54E+06 - - - 0.1305 - 2.091 0.418 - 179.9 1 2 0 0.0002 15 0 0 0 1.26E+07 1.27E+07 - - - 5.125 1 221125_WJC_METTL3_EV_vs_WT_F05.19033.19033.3 6.51E-12 25/88 K.VPAGVQELTHC[160.03]PDTPLLPPSDSR.G tr|H7C0V5|H7C0V5_HUMAN 1 2485.2271 1.7 69957 19033 3 2485.228331 829.4163 ANKHD1-EIF4EBP3 readthrough (Fragment) OS=Homo sapiens OX=9606 GN=ANKHD1-EIF4EBP3 PE=4 SV=1 4.54 3185 - 1.18E+06 - - - 0.4857 - 3.471 0.66 - 407 1 2 0 0.0012 23 0 0 0 3.35E+07 1.98E+07 - - - 8.8174 1 221125_WJC_METTL3_EV_vs_WT_F05.19034.19034.3 9.14E-11 14/64 K.SHC[160.03]FVTYSTVEEAVATR.T "sp|Q9UKV3|ACINU_HUMAN,tr|G3V3B0|G3V3B0_HUMAN,tr|S4R3H4|S4R3H4_HUMAN,tr|E7EQT4|E7EQT4_HUMAN" 4 1955.9047 0.84 69958 19034 3 1955.90518 652.9755 Apoptotic chromatin condensation inducer in the nucleus OS=Homo sapiens OX=9606 GN=ACIN1 PE=1 SV=2 5.38 3185.1 - 881881 - - - 0.2316 - 3.096 0.62 - 301.9 1 2 0 0.0005 17 0 0 0 5.60E+06 6.69E+06 - - - 8.3073 1 221125_WJC_METTL3_EV_vs_WT_F05.19035.19035.3 2.18E-11 22/80 K.TFPTVNPTTGEVIGHVAEGDR.A "sp|P30837|AL1B1_HUMAN,tr|A0A0U1RQK9|A0A0U1RQK9_HUMAN" 2 2196.0811 2.83 69959 19035 3 2196.082713 733.0343 "Aldehyde dehydrogenase X, mitochondrial OS=Homo sapiens OX=9606 GN=ALDH1B1 PE=1 SV=3" 4.65 3185.2 - 748225 - - - 0.7295 - 3.717 0.636 - 498.7 1 2 0 0.0016 21 0 0 0 4.44E+06 1.57E+06 - - - 8.778 1 221125_WJC_METTL3_EV_vs_WT_F05.19037.19037.3 6.45E-14 25/88 K.VPAGVQELTHC[160.03]PDTPLLPPSDSR[166.11].G tr|H7C0V5|H7C0V5_HUMAN 1 2495.2354 1.88 69961 19037 3 2495.235674 832.7524 ANKHD1-EIF4EBP3 readthrough (Fragment) OS=Homo sapiens OX=9606 GN=ANKHD1-EIF4EBP3 PE=4 SV=1 4.54 3185.4 - 687350 - - - 0.1122 - 4.049 0.695 - 419.8 1 2 0 0.0003 23 0 0 0 3.04E+07 1.62E+07 - - - 9.5692 1 221125_WJC_METTL3_EV_vs_WT_F05.19038.19038.3 8.31E-07 17/84 R.APVPEPGLDLSLSPR[166.11]PDSPQPR[166.11].H sp|Q8TAP8|PPR35_HUMAN 1 2344.229 2.18 69962 19038 3 2344.226294 782.4169 Protein phosphatase 1 regulatory subunit 35 OS=Homo sapiens OX=9606 GN=PPP1R35 PE=1 SV=1 4.56 3185.6 - 666006 - - - -1.1543 - 2.574 0.473 - 262.9 1 2 0 -0.0027 22 0 0 0 1.20E+07 5.51E+06 - - - 6.0543 0.9886 221125_WJC_METTL3_EV_vs_WT_F05.19040.19040.3 0.0243 Jul-40 K.EIKDILIQYDR.T "sp|P62249|RS16_HUMAN,tr|M0R210|M0R210_HUMAN" 2 1404.7613 0.74 69964 19040 3 1404.759601 469.261 40S ribosomal protein S16 OS=Homo sapiens OX=9606 GN=RPS16 PE=1 SV=2 4.56 3185.8 - 567475 - - - -1.1952 - 1.571 0.262 - 100.7 1 2 1 -0.0017 11 0 0 0 2.80E+06 3.78E+06 - - - 2.7438 0.9997 221125_WJC_METTL3_EV_vs_WT_F05.19041.19041.4 0.000206 14/72 R.KAHQLWLSVEALK.Y "sp|Q16891|MIC60_HUMAN,tr|B9A067|B9A067_HUMAN,tr|C9J406|C9J406_HUMAN,tr|H7C463|H7C463_HUMAN" 4 1521.8667 1.22 69965 19041 4 1521.862744 381.474 MICOS complex subunit MIC60 OS=Homo sapiens OX=9606 GN=IMMT PE=1 SV=1 8.6 3186 - 367612 - - - -2.631 - 2.914 0.393 - 225.8 1 2 0 -0.004 13 0 0 0 7.57E+06 6.19E+06 - - - 3.0421 1 221125_WJC_METTL3_EV_vs_WT_F05.19042.19042.3 2.24E-08 19/104 K.LTGAGGGGC[160.03]GITLLK[136.11]PGLEQPEVEATK[136.11].Q "sp|Q03426|KIME_HUMAN,tr|A0A0B4J236|A0A0B4J236_HUMAN,tr|F5H8H2|F5H8H2_HUMAN,tr|A0A1B0GWC2|A0A1B0GWC2_HUMAN" 4 2668.4077 1.33 69966 19042 3 2668.398765 890.4765 Mevalonate kinase OS=Homo sapiens OX=9606 GN=MVK PE=1 SV=1 4.79 3186.1 - 311923 - - - -3.3361 - 3.865 0.61 - 235.1 1 2 0 -0.0089 27 0 0 0 3.84E+06 2.88E+06 - - - 8.4488 1 221125_WJC_METTL3_EV_vs_WT_F05.19050.19050.3 1.58E-05 17/48 R.K[136.11]AHQLWLSVEALK[136.11].Y "sp|Q16891|MIC60_HUMAN,tr|B9A067|B9A067_HUMAN,tr|C9J406|C9J406_HUMAN,tr|H7C463|H7C463_HUMAN" 4 1537.8951 1.72 69972 19050 3 1537.893497 513.639 MICOS complex subunit MIC60 OS=Homo sapiens OX=9606 GN=IMMT PE=1 SV=1 8.6 3187.1 - 1.16E+06 - - - -1.0735 - 2.793 0.499 - 406.1 1 2 0 -0.0017 13 0 0 0 2.20E+07 1.28E+07 - - - 6.8877 1 221125_WJC_METTL3_EV_vs_WT_F05.19053.19053.3 4.17E-09 19/84 R.APVPEPGLDLSLSPRPDSPQPR.H sp|Q8TAP8|PPR35_HUMAN 1 2324.2125 2.2 69975 19053 3 2324.21243 775.7448 Protein phosphatase 1 regulatory subunit 35 OS=Homo sapiens OX=9606 GN=PPP1R35 PE=1 SV=1 4.56 3187.5 - 1.29E+06 - - - -0.0129 - 2.97 0.541 - 352.6 1 2 0 0 22 0 0 0 1.21E+07 5.51E+06 - - - 7.1524 1 221125_WJC_METTL3_EV_vs_WT_F05.19058.19058.3 2.23E-09 21/80 R.QHLGATGGPGAQLGASFLQAR[166.11].H "sp|Q9NWW5|CLN6_HUMAN,tr|H3BUT1|H3BUT1_HUMAN,tr|A0A1B0GTV3|A0A1B0GTV3_HUMAN,tr|H3BNF1|H3BNF1_HUMAN,tr|A0A1B0GW73|A0A1B0GW73_HUMAN,tr|A0A1B0GUD2|A0A1B0GUD2_HUMAN,tr|H3BUV4|H3BUV4_HUMAN,tr|A0A0S2Z5D0|A0A0S2Z5D0_HUMAN,tr|A0A1B0GTU6|A0A1B0GTU6_HUMAN,tr|H3BTY4|H3BTY4_HUMAN,tr|H3BRN7|H3BRN7_HUMAN" 11 2046.0634 1.22 69980 19058 3 2046.059088 683.0284 Ceroid-lipofuscinosis neuronal protein 6 OS=Homo sapiens OX=9606 GN=CLN6 PE=1 SV=1 9.76 3188.1 - 634812 - - - -2.1275 - 4.182 0.584 - 443.4 1 2 0 -0.0044 21 0 0 0 4.56E+06 3.73E+06 - - - 8.4801 0.9999 221125_WJC_METTL3_EV_vs_WT_F05.19059.19059.3 3.43E-07 19/68 R.DLAALGDKVNSLGETAER.L "sp|Q13813|SPTN1_HUMAN,tr|A0A0D9SF54|A0A0D9SF54_HUMAN,tr|A0A0D9SGF6|A0A0D9SGF6_HUMAN" 3 1857.9432 3.59 69981 19059 3 1857.941262 620.3217 "Spectrin alpha chain, non-erythrocytic 1 OS=Homo sapiens OX=9606 GN=SPTAN1 PE=1 SV=3" 4.32 3188.2 - 564969 - - - -1.0539 - 3.367 0.45 - 428.2 1 2 1 -0.002 18 0 0 0 4.35E+06 1.21E+06 - - - 6.5796 0.9998 221125_WJC_METTL3_EV_vs_WT_F05.19060.19060.4 0.0213 13/72 R.K[136.11]AHQLWLSVEALK[136.11].Y "sp|Q16891|MIC60_HUMAN,tr|B9A067|B9A067_HUMAN,tr|C9J406|C9J406_HUMAN,tr|H7C463|H7C463_HUMAN" 4 1537.8951 1.23 69982 19060 4 1537.891826 385.4811 MICOS complex subunit MIC60 OS=Homo sapiens OX=9606 GN=IMMT PE=1 SV=1 8.6 3188.3 - 466888 - - - -2.1601 - 2.538 0.418 - 118.2 1 2 0 -0.0033 13 0 0 0 7.60E+06 6.19E+06 - - - 3.2087 0.9998 221125_WJC_METTL3_EV_vs_WT_F05.19062.19062.3 1.82E-05 13/68 K.WLK[136.11]EDK[136.11]LEC[160.03]SEELGDLVK[136.11].S "sp|Q00610|CLH1_HUMAN,sp|P53675|CLH2_HUMAN,tr|A0A087WVQ6|A0A087WVQ6_HUMAN,tr|A0A087WX41|A0A087WX41_HUMAN" 4 2214.1304 0.95 69984 19062 3 2214.129872 739.0508 Clathrin heavy chain 1 OS=Homo sapiens OX=9606 GN=CLTC PE=1 SV=5 4.36 3188.6 - 352263 - - - -0.2547 - 2.514 0.463 - 177.2 1 2 2 -0.0006 18 0 0 0 2.44E+06 2.56E+06 - - - 5.9974 1 221125_WJC_METTL3_EV_vs_WT_F05.19064.19064.3 7.64E-07 15/80 K.TFPTVNPTTGEVIGHVAEGDR[166.11].A "sp|P30837|AL1B1_HUMAN,tr|A0A0U1RQK9|A0A0U1RQK9_HUMAN" 2 2206.0894 2.65 69986 19064 3 2206.083723 736.3704 "Aldehyde dehydrogenase X, mitochondrial OS=Homo sapiens OX=9606 GN=ALDH1B1 PE=1 SV=3" 4.65 3188.9 - 329536 - - - -2.5647 - 3.018 0.568 - 196.2 1 2 0 -0.0057 21 0 0 0 4.16E+06 1.57E+06 - - - 7.5193 1 221125_WJC_METTL3_EV_vs_WT_F05.19068.19068.3 4.57E-05 23/68 R.RAEDGSVIDYELIDQDAR.D "sp|P07355|ANXA2_HUMAN,tr|H0YL33|H0YL33_HUMAN,tr|H0YMU9|H0YMU9_HUMAN,tr|H0YNA0|H0YNA0_HUMAN,tr|H0YM50|H0YM50_HUMAN,tr|H0YMD0|H0YMD0_HUMAN,tr|H0YMW4|H0YMW4_HUMAN,tr|H0YN42|H0YN42_HUMAN,tr|H0YN28|H0YN28_HUMAN,tr|H0YNP5|H0YNP5_HUMAN" 10 2063.976 4.34 69988 19068 3 2063.977915 688.9993 Annexin A2 OS=Homo sapiens OX=9606 GN=ANXA2 PE=1 SV=2 3.96 3189.3 - 2.62E+06 - - - 0.939 - 4.246 0.669 - 905.4 1 2 0 0.0019 18 0 0 0 4.06E+07 9.35E+06 - - - 9.5988 1 221125_WJC_METTL3_EV_vs_WT_F05.19071.19071.3 2.13E-08 19/92 K.IQALPTVPVTEEHVGSGLEC[160.03]PVC[160.03]K[136.11].D "sp|Q9BV68|RN126_HUMAN,tr|K7EIY6|K7EIY6_HUMAN" 2 2627.3179 2.21 69991 19071 3 2627.312776 876.7799 E3 ubiquitin-protein ligase RNF126 OS=Homo sapiens OX=9606 GN=RNF126 PE=1 SV=2 4.75 3189.5 - 1.21E+06 - - - -1.9351 - 3.182 0.6 - 248.5 1 2 0 -0.0051 24 0 0 0 1.51E+07 6.82E+06 - - - 7.9164 0.9999 221125_WJC_METTL3_EV_vs_WT_F05.19072.19072.3 0.000101 13/44 R.GMQDLVEDFKNK.Y sp|P02538|K2C6A_HUMAN 1 1422.6813 1093.5 69992 19072 3 1422.680384 475.2344 "Keratin, type II cytoskeletal 6A OS=Homo sapiens OX=9606 GN=KRT6A PE=1 SV=3" 4.56 3189.6 - 912290 - - - -0.6544 - 2.609 0.498 - 165.6 1 2 1 -0.0009 12 0 0 0 3.20E+07 2.93E+04 - - - 6.7501 0.9998 221125_WJC_METTL3_EV_vs_WT_F05.19078.19078.3 0.00288 Aug-48 K.ANDLTHSLSSYLK[136.11].E "sp|Q9BQ75|CMS1_HUMAN,tr|C9J384|C9J384_HUMAN,tr|H7C515|H7C515_HUMAN" 3 1455.7449 0.5 69998 19078 3 1455.744074 486.2556 Protein CMSS1 OS=Homo sapiens OX=9606 GN=CMSS1 PE=1 SV=2 6.79 3190.4 - 262403 - - - -0.5729 - 1.984 0.364 - 91.3 1 2 0 -0.0008 13 0 0 0 7.89E+05 1.58E+06 - - - 4.4556 1 221125_WJC_METTL3_EV_vs_WT_F05.19080.19080.2 2.67E-11 13/32 K.NDDIPEQDSLGLSNLQK.S tr|Q9HB66|Q9HB66_HUMAN 1 1884.9065 10.6 70000 19080 2 1884.905027 943.4605 Alternative protein MKKS OS=Homo sapiens OX=9606 GN=MKKS PE=1 SV=1 3.84 3190.7 - 157669 - - - -0.782 - 2.379 0.688 - 408.6 1 2 0 -0.0015 17 0 0 0 1.09E+06 1.03E+05 - - - 6.2529 1 221125_WJC_METTL3_EV_vs_WT_F05.19083.19083.3 3.00E-08 15/56 R.SDPTSYAGYIEDLK[136.11]K[136.11].F "sp|P54709|AT1B3_HUMAN,tr|C9JA36|C9JA36_HUMAN,tr|C9JXZ1|C9JXZ1_HUMAN" 3 1701.8432 1.3 70001 19083 3 1701.842383 568.2884 Sodium\potassium-transporting ATPase subunit beta-3 OS=Homo sapiens OX=9606 GN=ATP1B3 PE=1 SV=1 4.56 3191.1 - 794796 - - - -0.4989 - 3.056 0.602 - 265.1 1 2 0 -0.0008 15 0 0 0 7.19E+07 5.54E+07 - - - 8.1664 1 221125_WJC_METTL3_EV_vs_WT_F05.19084.19084.3 4.10E-07 13/56 R.SDPTSYAGYIEDLKK.F "sp|P54709|AT1B3_HUMAN,tr|C9JA36|C9JA36_HUMAN,tr|C9JXZ1|C9JXZ1_HUMAN" 3 1685.8148 1.29 70002 19084 3 1685.814279 562.9456 Sodium\potassium-transporting ATPase subunit beta-3 OS=Homo sapiens OX=9606 GN=ATP1B3 PE=1 SV=1 4.56 3191.2 - 800641 - - - -0.328 - 2.537 0.522 - 191.5 1 2 0 -0.0006 15 0 0 0 7.19E+07 5.56E+07 - - - 6.7889 0.9997 221125_WJC_METTL3_EV_vs_WT_F05.19089.19089.3 5.88E-06 Dec-88 K.IGSNNSTTPTVPLK[136.11]PPPPLTLGK[136.11].T "sp|Q96CB8|INT12_HUMAN,tr|A0A087WXN4|A0A087WXN4_HUMAN" 2 2344.3337 0.95 70007 19089 3 2344.335313 782.4518 Integrator complex subunit 12 OS=Homo sapiens OX=9606 GN=INTS12 PE=1 SV=1 10 3191.9 - 471119 - - - 0.6893 - 2.06 0.352 - 97.5 1 2 0 0.0016 23 0 0 0 1.09E+07 1.15E+07 - - - 4.1594 1 221125_WJC_METTL3_EV_vs_WT_F05.19093.19093.2 6.97E-11 26-Sep K.C[160.03]PNPTC[160.03]ENMNFSWR.N "sp|P35637|FUS_HUMAN,tr|H3BPE7|H3BPE7_HUMAN" 2 1811.7178 0.43 70011 19093 2 1811.716363 906.8662 RNA-binding protein FUS OS=Homo sapiens OX=9606 GN=FUS PE=1 SV=1 5.99 3192.4 - 309640 - - - -0.7904 - 2.355 0.774 - 248.2 1 2 0 -0.0014 14 0 0 0 2.97E+06 6.87E+06 - - - 6.9068 1 221125_WJC_METTL3_EV_vs_WT_F05.19094.19094.2 1.65E-06 13/26 K.C[160.03]PNPTC[160.03]ENMNFSWR[166.11].N "sp|P35637|FUS_HUMAN,tr|H3BPE7|H3BPE7_HUMAN" 2 1821.7261 0.43 70012 19094 2 1821.722686 911.8703 RNA-binding protein FUS OS=Homo sapiens OX=9606 GN=FUS PE=1 SV=1 5.99 3192.5 - 305468 - - - -1.8548 - 2.446 0.663 - 644.7 1 2 0 -0.0034 14 0 0 0 2.97E+06 6.87E+06 - - - 6.1814 0.9998 221125_WJC_METTL3_EV_vs_WT_F05.19096.19096.3 0.00272 Nov-76 K.EDSAPSKPVVGIIYPPPEVR.N "sp|Q15459|SF3A1_HUMAN,tr|F8WB66|F8WB66_HUMAN" 2 2149.1419 1.92 70014 19096 3 2149.138838 717.3879 Splicing factor 3A subunit 1 OS=Homo sapiens OX=9606 GN=SF3A1 PE=1 SV=1 4.68 3192.8 - 215801 - - - -1.4341 - 2.362 0.371 - 107.5 1 2 0 -0.0031 20 0 0 0 3.15E+06 1.64E+06 - - - 4.7606 0.9986 221125_WJC_METTL3_EV_vs_WT_F05.19098.19098.3 0.000746 23/76 M.RILSAENIPNLPPGGGLAGK.R "sp|O75688|PPM1B_HUMAN,tr|B8ZZF0|B8ZZF0_HUMAN,tr|A0A3B3IS24|A0A3B3IS24_HUMAN,tr|C9JIR6|C9JIR6_HUMAN" 4 1973.1058 5.68 70015 19098 3 1973.108585 658.7092 Protein phosphatase 1B OS=Homo sapiens OX=9606 GN=PPM1B PE=1 SV=1 8.75 3193 - 715492 - - - 1.4064 - 3.742 0.592 - 524.7 1 1 0 0.0028 20 0 0 0 1.22E+07 2.15E+06 - - - 8.3409 1 221125_WJC_METTL3_EV_vs_WT_F05.19101.19101.3 2.19E-07 19/56 K.TGENVEDAFLEAAK[136.11]K[136.11].L "sp|P61106|RAB14_HUMAN,tr|X6RFL8|X6RFL8_HUMAN" 2 1636.8279 1.06 70017 19101 3 1636.826405 546.6166 Ras-related protein Rab-14 OS=Homo sapiens OX=9606 GN=RAB14 PE=1 SV=4 4.41 3193.3 - 1.44E+06 - - - -0.9231 - 3.39 0.637 - 478.8 1 2 0 -0.0015 15 0 0 0 1.62E+07 1.53E+07 - - - 8.8271 1 221125_WJC_METTL3_EV_vs_WT_F05.19107.19107.3 9.78E-10 18/80 K.IC[160.03]DQISDAVLDAHLQQDPDAK.V sp|P31153|METK2_HUMAN 1 2351.1063 1.75 70023 19107 3 2351.109906 784.7094 S-adenosylmethionine synthase isoform type-2 OS=Homo sapiens OX=9606 GN=MAT2A PE=1 SV=1 3.97 3194 - 621223 - - - 1.5167 - 4.028 0.615 - 338.2 1 2 0 0.0036 21 0 0 0 6.52E+06 3.73E+06 - - - 8.736 1 221125_WJC_METTL3_EV_vs_WT_F05.19111.19111.3 1.39E-07 17/56 R.MGPLGLDHMASSIER.M "sp|P52272|HNRPM_HUMAN,tr|A0A087X0X3|A0A087X0X3_HUMAN,tr|M0QZM1|M0QZM1_HUMAN" 3 1612.7701 79.2 70027 19111 3 1612.77096 538.5973 Heterogeneous nuclear ribonucleoprotein M OS=Homo sapiens OX=9606 GN=HNRNPM PE=1 SV=3 5.3 3194.6 - 279797 - - - 0.5041 - 3.335 0.509 - 547.6 1 2 0 0.0008 15 0 0 0 3.52E+06 4.44E+04 - - - 7.3575 1 221125_WJC_METTL3_EV_vs_WT_F05.19115.19115.3 1.93E-11 25/76 K.ANC[160.03]IDSTASAEAVFASEVKK.M "sp|P22087|FBRL_HUMAN,tr|M0R299|M0R299_HUMAN,tr|M0QXL5|M0QXL5_HUMAN,tr|M0R2Q4|M0R2Q4_HUMAN" 4 2097.0048 0.7 70029 19115 3 2097.006094 700.0089 rRNA 2'-O-methyltransferase fibrillarin OS=Homo sapiens OX=9606 GN=FBL PE=1 SV=2 4.68 3195.1 - 2.39E+06 - - - 0.6004 - 4.359 0.663 - 913.3 1 2 0 0.0013 20 0 0 0 2.84E+07 4.08E+07 - - - 9.5031 1 221125_WJC_METTL3_EV_vs_WT_F05.19118.19118.2 1.60E-05 15/30 K.DIDDDLEGEVTEEC[160.03]GK[136.11].F "sp|Q9UHX1|PUF60_HUMAN,tr|A0A0J9YYL3|A0A0J9YYL3_HUMAN,tr|A0A0J9YXX5|A0A0J9YXX5_HUMAN,tr|A0A0J9YXJ8|A0A0J9YXJ8_HUMAN,tr|A0A0J9YVP6|A0A0J9YVP6_HUMAN" 5 1830.7557 1.28 70032 19118 2 1830.757217 916.3851 Poly(U)-binding-splicing factor PUF60 OS=Homo sapiens OX=9606 GN=PUF60 PE=1 SV=1 3.58 3195.4 - 650148 - - - 0.8456 - 3.33 0.653 - 616.9 1 2 0 0.0015 16 0 0 0 1.17E+07 9.18E+06 - - - 6.8211 0.9995 221125_WJC_METTL3_EV_vs_WT_F05.19120.19120.3 3.14E-10 21/88 K.IGSNNSTTPTVPLKPPPPLTLGK.T "sp|Q96CB8|INT12_HUMAN,tr|A0A087WXN4|A0A087WXN4_HUMAN" 2 2328.3053 1.07 70034 19120 3 2328.317184 777.109 Integrator complex subunit 12 OS=Homo sapiens OX=9606 GN=INTS12 PE=1 SV=1 10 3195.6 - 483656 - - - 5.1054 - 3.326 0.478 - 345.1 1 2 0 0.0119 23 0 0 0 1.09E+07 1.02E+07 - - - 6.6852 1 221125_WJC_METTL3_EV_vs_WT_F05.19123.19123.3 8.23E-08 16/76 K.ETTYYDVLGVKPNATQEELK.K sp|P31689|DNJA1_HUMAN 1 2297.1427 0.59 70037 19123 3 2297.147808 766.7215 DnaJ homolog subfamily A member 1 OS=Homo sapiens OX=9606 GN=DNAJA1 PE=1 SV=2 4.41 3196 - 427984 - - - 2.2201 - 3.155 0.569 - 225.1 1 2 0 0.0051 20 0 0 0 9.02E+06 1.52E+07 - - - 7.6698 1 221125_WJC_METTL3_EV_vs_WT_F05.19125.19125.3 9.32E-06 17/56 K.AEDNFEDIITK[136.11]PPVR[166.11].K "sp|Q9Y6G9|DC1L1_HUMAN,tr|E9PHI6|E9PHI6_HUMAN" 2 1760.9064 1.38 70039 19125 3 1760.908054 587.9761 Cytoplasmic dynein 1 light intermediate chain 1 OS=Homo sapiens OX=9606 GN=DYNC1LI1 PE=1 SV=3 4.32 3196.3 - 367687 - - - 0.9478 - 3.319 0.649 - 428.2 1 2 0 0.0017 15 0 0 0 5.73E+06 4.16E+06 - - - 8.9056 0.9997 221125_WJC_METTL3_EV_vs_WT_F05.19126.19126.3 0.00145 Jul-44 R.LPVDLAEELGHR.D "sp|P42771|CDN2A_HUMAN,tr|K7ENC6|K7ENC6_HUMAN,tr|J3QRG6|J3QRG6_HUMAN,tr|K7ES20|K7ES20_HUMAN" 4 1347.7147 1.32 70040 19126 3 1347.714764 450.2455 Cyclin-dependent kinase inhibitor 2A OS=Homo sapiens OX=9606 GN=CDKN2A PE=1 SV=2 4.65 3196.4 - 204701 - - - 0.0742 - 1.799 0.359 - 49.9 1 2 0 0.0001 12 0 0 0 1.90E+06 1.44E+06 - - - 4.1702 1 221125_WJC_METTL3_EV_vs_WT_F05.19131.19131.3 1.07E-09 16/68 R.GK[136.11]PPPLLPSVLGPAGGDR[166.11].E "sp|Q8IY67|RAVR1_HUMAN,tr|E9PAU2|E9PAU2_HUMAN,tr|A0A087WZ13|A0A087WZ13_HUMAN" 3 1744.9955 1.02 70043 19131 3 1744.995494 582.6724 Ribonucleoprotein PTB-binding 1 OS=Homo sapiens OX=9606 GN=RAVER1 PE=1 SV=1 8.75 3197 - 778147 - - - 0.0115 - 3.206 0.59 - 321.8 1 2 0 0 18 0 0 0 4.39E+07 4.32E+07 - - - 8.0189 1 221125_WJC_METTL3_EV_vs_WT_F05.19133.19133.3 6.98E-10 18/72 K.VQGGALEDSQLVAGVAFK[136.11]K[136.11].T sp|Q99832|TCPH_HUMAN 1 1932.0651 2.06 70045 19133 3 1932.064203 645.029 T-complex protein 1 subunit eta OS=Homo sapiens OX=9606 GN=CCT7 PE=1 SV=2 6.04 3197.3 - 588365 - - - -0.4782 - 3.569 0.624 - 414.8 1 2 0 -0.0009 19 0 0 0 1.12E+07 5.42E+06 - - - 8.6225 1 221125_WJC_METTL3_EV_vs_WT_F05.19134.19134.3 5.53E-07 16/64 K.K[136.11]ANLQIDQINTDLNLER[166.11].S sp|P35579|MYH9_HUMAN 1 2015.0766 0.98 70046 19134 3 2015.07493 672.6995 Myosin-9 OS=Homo sapiens OX=9606 GN=MYH9 PE=1 SV=4 4.56 3197.4 - 542335 - - - -0.8476 - 3.376 0.563 - 441.7 1 2 0 -0.0017 17 0 0 0 1.14E+07 1.16E+07 - - - 7.8902 1 221125_WJC_METTL3_EV_vs_WT_F05.19140.19140.3 0.00317 24/80 R.GQVGGDVNVEMDAAPGVDLSR.L sp|P02533|K1C14_HUMAN 1 2084.9797 1.03 70050 19140 3 2084.979569 696.0005 "Keratin, type I cytoskeletal 14 OS=Homo sapiens OX=9606 GN=KRT14 PE=1 SV=4" 3.84 3198.1 - 771662 - - - -0.0542 - 4.187 0.608 - 445.1 1 2 0 -0.0001 21 0 0 0 2.15E+07 2.08E+07 - - - 8.7517 1 221125_WJC_METTL3_EV_vs_WT_F05.19141.19141.3 2.09E-10 19/68 R.GKPPPLLPSVLGPAGGDR.E "sp|Q8IY67|RAVR1_HUMAN,tr|E9PAU2|E9PAU2_HUMAN,tr|A0A087WZ13|A0A087WZ13_HUMAN" 3 1726.973 1.01 70051 19141 3 1726.970246 576.6649 Ribonucleoprotein PTB-binding 1 OS=Homo sapiens OX=9606 GN=RAVER1 PE=1 SV=1 8.75 3198.2 - 999528 - - - -1.597 - 3.38 0.653 - 395.4 1 2 0 -0.0028 18 0 0 0 4.37E+07 4.32E+07 - - - 8.8522 1 221125_WJC_METTL3_EV_vs_WT_F05.19142.19142.4 5.61E-08 20/102 K.VTSEELHYFVQNHFTSAR[166.11].M "sp|P22695|QCR2_HUMAN,tr|H3BRG4|H3BRG4_HUMAN,tr|H3BSJ9|H3BSJ9_HUMAN" 3 2174.042 1.38 70052 19142 4 2174.042269 544.5178 "Cytochrome b-c1 complex subunit 2, mitochondrial OS=Homo sapiens OX=9606 GN=UQCRC2 PE=1 SV=3" 6 3198.4 - 686690 - - - 0.1067 - 3.762 0.535 - 342.7 1 2 0 0.0002 18 0 0 0 1.15E+07 8.32E+06 - - - 4.3364 1 221125_WJC_METTL3_EV_vs_WT_F05.19143.19143.3 5.86E-09 18/72 R.QFLLQQASGLSSPGNNDSK.Q "sp|Q8IVH2|FOXP4_HUMAN,tr|B7ZBM3|B7ZBM3_HUMAN,tr|A2A312|A2A312_HUMAN" 3 1989.9756 7.02 70053 19143 3 1989.973012 664.3325 Forkhead box protein P4 OS=Homo sapiens OX=9606 GN=FOXP4 PE=1 SV=1 5.84 3198.5 - 535064 - - - -1.292 - 3.803 0.585 - 313.9 1 2 0 -0.0026 19 0 0 0 1.16E+07 1.65E+06 - - - 8.3432 1 221125_WJC_METTL3_EV_vs_WT_F05.19144.19144.2 6.44E-17 20/40 R.GQVGGDVNVEMDAAPGVDLSR.L sp|P02533|K1C14_HUMAN 1 2084.9797 999 70054 19144 2 2084.977064 1043.4971 "Keratin, type I cytoskeletal 14 OS=Homo sapiens OX=9606 GN=KRT14 PE=1 SV=4" 3.84 3198.6 - 436446 - - - -1.2556 - 3.831 0.736 - 747.3 1 2 0 -0.0026 21 0 0 0 8.95E+06 0.00E+00 - - - 7.7784 0.9987 221125_WJC_METTL3_EV_vs_WT_F05.19145.19145.3 1.66E-09 14/48 D.PTSYAGYIEDLKK.F "sp|P54709|AT1B3_HUMAN,tr|C9JA36|C9JA36_HUMAN,tr|C9JXZ1|C9JXZ1_HUMAN" 3 1483.7559 2.01 70055 19145 3 1483.756449 495.5926 Sodium\potassium-transporting ATPase subunit beta-3 OS=Homo sapiens OX=9606 GN=ATP1B3 PE=1 SV=1 6.48 3198.7 - 160182 - - - 0.3963 - 2.901 0.574 - 154 1 1 0 0.0006 13 0 0 0 9.12E+05 4.54E+05 - - - 7.827 0.9849 221125_WJC_METTL3_EV_vs_WT_F05.19151.19151.2 0.842 16-Jul R.LLLPGELAK.H "sp|Q8N257|H2B3B_HUMAN,sp|A0A2R8Y619|H2BE1_HUMAN,sp|P33778|H2B1B_HUMAN,sp|Q96A08|H2B1A_HUMAN,sp|Q5QNW6|H2B2F_HUMAN,sp|P58876|H2B1D_HUMAN,sp|Q99880|H2B1L_HUMAN,sp|P62807|H2B1C_HUMAN,sp|Q99877|H2B1N_HUMAN,sp|P57053|H2BFS_HUMAN,sp|P23527|H2B1O_HUMAN,sp|O60814|H2B1K_HUMAN,sp|Q93079|H2B1H_HUMAN,sp|Q99879|H2B1M_HUMAN,sp|Q16778|H2B2E_HUMAN,sp|P06899|H2B1J_HUMAN,tr|U3KQK0|U3KQK0_HUMAN" 17 952.5957 1.74 70059 19151 2 952.597749 477.3051 Histone H2B type 3-B OS=Homo sapiens OX=9606 GN=H2BU1 PE=1 SV=3 6 3199.5 - 416755 - - - 2.1321 - 1.208 0.187 - 128.6 1 2 0 0.002 9 0 0 0 7.24E+06 4.17E+06 - - - 0.9682 0.9998 221125_WJC_METTL3_EV_vs_WT_F05.19153.19153.3 3.60E-06 Dec-52 K.LEDK[136.11]VENLVDQLNK[136.11].S "sp|Q15643|TRIPB_HUMAN,tr|H0YJ97|H0YJ97_HUMAN" 2 1671.9014 1.46 70061 19153 3 1671.899658 558.3077 Thyroid receptor-interacting protein 11 OS=Homo sapiens OX=9606 GN=TRIP11 PE=1 SV=3 4.32 3199.8 - 356450 - - - -1.0515 - 2.592 0.454 - 220.3 1 2 1 -0.0018 14 0 0 0 2.75E+07 1.89E+07 - - - 6.1323 0.9995 221125_WJC_METTL3_EV_vs_WT_F05.19154.19154.3 4.36E-06 14/52 K.LEDKVENLVDQLNK.S "sp|Q15643|TRIPB_HUMAN,tr|H0YJ97|H0YJ97_HUMAN" 2 1655.873 1.46 70062 19154 3 1655.878101 552.9649 Thyroid receptor-interacting protein 11 OS=Homo sapiens OX=9606 GN=TRIP11 PE=1 SV=3 4.32 3199.9 - 328444 - - - 3.0709 - 2.719 0.492 - 295.6 1 2 1 0.0051 14 0 0 0 2.75E+07 1.89E+07 - - - 6.6821 1 221125_WJC_METTL3_EV_vs_WT_F05.19156.19156.2 1.06E-10 15/36 R.QFLLQQASGLSSPGNNDSK.Q "sp|Q8IVH2|FOXP4_HUMAN,tr|B7ZBM3|B7ZBM3_HUMAN,tr|A2A312|A2A312_HUMAN" 3 1989.9756 6.44 70064 19156 2 1989.971761 995.9951 Forkhead box protein P4 OS=Homo sapiens OX=9606 GN=FOXP4 PE=1 SV=1 5.84 3200.2 - 273837 - - - -1.9206 - 3.319 0.698 - 518.8 1 2 0 -0.0038 19 0 0 0 4.42E+06 6.86E+05 - - - 7.1447 0.9999 221125_WJC_METTL3_EV_vs_WT_F05.19157.19157.3 0.00123 Nov-40 K.KSAEFLLHMLK.N "sp|P18621|RL17_HUMAN,tr|A0A087WWH0|A0A087WWH0_HUMAN,tr|J3QS96|J3QS96_HUMAN,tr|J3QLC8|J3QLC8_HUMAN,tr|J3QQT2|J3QQT2_HUMAN,tr|A0A087WY81|A0A087WY81_HUMAN,tr|A0A0A0MRF8|A0A0A0MRF8_HUMAN,tr|J3KRB3|J3KRB3_HUMAN,tr|J3KRX5|J3KRX5_HUMAN,tr|A0A087WXM6|A0A087WXM6_HUMAN,tr|A0A0A6YYL6|A0A0A6YYL6_HUMAN" 11 1315.7322 0.94 70065 19157 3 1315.732716 439.5847 60S ribosomal protein L17 OS=Homo sapiens OX=9606 GN=RPL17 PE=1 SV=3 8.6 3200.3 - 239085 - - - 0.3701 - 2.362 0.418 - 193.3 1 2 0 0.0005 11 0 0 0 1.31E+07 1.39E+07 - - - 5.6419 0.9999 221125_WJC_METTL3_EV_vs_WT_F05.19158.19158.3 0.00102 Oct-44 K.KGTNYLADVFEK.K sp|P31151|S10A7_HUMAN 1 1383.7034 361.23 70066 19158 3 1383.702291 462.2418 Protein S100-A7 OS=Homo sapiens OX=9606 GN=S100A7 PE=1 SV=4 6.07 3200.4 - 207358 - - - -0.8239 - 1.739 0.428 - 170.7 1 2 0 -0.0011 12 0 0 0 1.57E+07 4.36E+04 - - - 4.8452 1 221125_WJC_METTL3_EV_vs_WT_F05.19162.19162.3 6.66E-06 16/60 K.KVDDDLGTIESLEEAK.K sp|P35580|MYH10_HUMAN 1 1760.868 0.79 70068 19162 3 1760.865572 587.9633 Myosin-10 OS=Homo sapiens OX=9606 GN=MYH10 PE=1 SV=3 4.02 3201 - 727773 - - - -1.3732 - 3.065 0.515 - 420.6 1 2 0 -0.0024 16 0 0 0 1.14E+07 1.44E+07 - - - 7.155 1 221125_WJC_METTL3_EV_vs_WT_F05.19163.19163.3 6.73E-11 22/92 K.GGPGSAVSPYPTFNPSSDVAALHK.A "sp|P04083|ANXA1_HUMAN,tr|Q5T3N1|Q5T3N1_HUMAN,tr|Q5T3N0|Q5T3N0_HUMAN" 3 2355.1495 3.27 70069 19163 3 2355.153643 786.0571 Annexin A1 OS=Homo sapiens OX=9606 GN=ANXA1 PE=1 SV=2 6.74 3201.1 - 531054 - - - 1.7485 - 4.414 0.608 - 452.8 1 2 0 0.0041 24 0 0 0 1.19E+07 3.64E+06 - - - 8.766 1 221125_WJC_METTL3_EV_vs_WT_F05.19165.19165.3 0.00519 14/56 K.K[136.11]MEEEILLLEDQNSK[136.11].F sp|P35580|MYH10_HUMAN 1 1833.9365 0.85 70071 19165 3 1833.933227 612.3194 Myosin-10 OS=Homo sapiens OX=9606 GN=MYH10 PE=1 SV=3 4.25 3201.4 - 343884 - - - -1.7743 - 2.863 0.472 - 417.7 1 2 0 -0.0033 15 0 0 0 3.44E+06 4.05E+06 - - - 6.5461 1 221125_WJC_METTL3_EV_vs_WT_F05.19167.19167.3 5.04E-11 15/76 R.YDHGTFFPMGDEGASSQIGR.A "sp|Q9UBN7|HDAC6_HUMAN,tr|A0A2R8YDE6|A0A2R8YDE6_HUMAN" 2 2170.9378 1.32 70073 19167 3 2170.934367 724.6532 Histone deacetylase 6 OS=Homo sapiens OX=9606 GN=HDAC6 PE=1 SV=2 4.54 3201.6 - 264314 - - - -1.5896 - 3.225 0.709 - 260.3 1 2 0 -0.0035 20 0 0 0 6.48E+06 4.89E+06 - - - 9.2844 1 221125_WJC_METTL3_EV_vs_WT_F05.19169.19169.4 0.00137 Dec-78 R.K[136.11]TVTAMDVVYALK[136.11]R[166.11].Q sp|P62805|H4_HUMAN 1 1619.9279 0.83 70075 19169 4 1619.927328 405.9893 Histone H4 OS=Homo sapiens OX=9606 GN=H4C1 PE=1 SV=2 9.7 3201.9 - 104189 - - - -0.3648 - 2.681 0.502 - 137 1 2 0 -0.0006 14 0 0 0 6.31E+06 7.59E+06 - - - 3.9542 1 221125_WJC_METTL3_EV_vs_WT_F05.19172.19172.3 5.20E-10 20/72 R.EDLMGLAIGTHGSNIQQAR.K "sp|P51114|FXR1_HUMAN,tr|E7EU85|E7EU85_HUMAN,tr|E9PFF5|E9PFF5_HUMAN,tr|B4DXZ6|B4DXZ6_HUMAN" 4 2009.9953 1.78 70076 19172 3 2009.997459 671.0057 Fragile X mental retardation syndrome-related protein 1 OS=Homo sapiens OX=9606 GN=FXR1 PE=1 SV=3 5.32 3202.3 - 1.34E+06 - - - 1.0876 - 3.849 0.611 - 614.9 1 2 0 0.0022 19 0 0 0 5.72E+07 3.21E+07 - - - 8.6628 1 221125_WJC_METTL3_EV_vs_WT_F05.19173.19173.3 9.90E-06 14/72 R.EDLMGLAIGTHGSNIQQAR[166.11].K "sp|P51114|FXR1_HUMAN,tr|E7EU85|E7EU85_HUMAN,tr|E9PFF5|E9PFF5_HUMAN,tr|B4DXZ6|B4DXZ6_HUMAN" 4 2020.0035 1.83 70077 19173 3 2020.005115 674.3418 Fragile X mental retardation syndrome-related protein 1 OS=Homo sapiens OX=9606 GN=FXR1 PE=1 SV=3 5.32 3202.4 - 881155 - - - 0.7782 - 3.235 0.532 - 230 1 2 0 0.0016 19 0 0 0 5.66E+07 3.10E+07 - - - 7.3552 1 221125_WJC_METTL3_EV_vs_WT_F05.19174.19174.3 4.75E-06 14/60 K.VELAQLQEEWNEHNAK.L sp|Q9H307|PININ_HUMAN 1 1936.9279 1.85 70078 19174 3 1936.928678 646.6499 Pinin OS=Homo sapiens OX=9606 GN=PNN PE=1 SV=5 4.48 3202.4 - 857279 - - - 0.3991 - 2.651 0.521 - 198.9 1 2 0 0.0008 16 0 0 0 1.22E+08 6.59E+07 - - - 6.85 1 221125_WJC_METTL3_EV_vs_WT_F05.19179.19179.3 1.32E-11 16/68 K.VTSEELHYFVQNHFTSAR.M "sp|P22695|QCR2_HUMAN,tr|H3BRG4|H3BRG4_HUMAN,tr|H3BSJ9|H3BSJ9_HUMAN" 3 2164.0338 2.94 70083 19179 3 2164.027936 722.3519 "Cytochrome b-c1 complex subunit 2, mitochondrial OS=Homo sapiens OX=9606 GN=UQCRC2 PE=1 SV=3" 6 3203.1 - 411032 - - - -2.6945 - 3.318 0.629 - 312.9 1 2 0 -0.0058 18 0 0 0 4.45E+06 1.51E+06 - - - 8.5376 1 221125_WJC_METTL3_EV_vs_WT_F05.19180.19180.3 1.73E-06 15/52 R.KTVTAMDVVYALKR.Q sp|P62805|H4_HUMAN 1 1593.8912 0.81 70084 19180 3 1593.892046 532.3044 Histone H4 OS=Homo sapiens OX=9606 GN=H4C1 PE=1 SV=2 9.7 3203.2 - 280301 - - - 0.5 - 3.131 0.573 - 421.4 1 2 0 0.0008 14 0 0 0 9.34E+06 1.15E+07 - - - 7.9613 0.9989 221125_WJC_METTL3_EV_vs_WT_F05.19181.19181.3 0.017 Jun-52 K.DAVFIPAGWDNDKK.L "sp|Q9Y6G9|DC1L1_HUMAN,tr|E9PHI6|E9PHI6_HUMAN" 2 1574.7729 0.72 70085 19181 3 1574.773415 525.9316 Cytoplasmic dynein 1 light intermediate chain 1 OS=Homo sapiens OX=9606 GN=DYNC1LI1 PE=1 SV=3 4.43 3203.4 - 240515 - - - 0.322 - 1.629 0.305 - 43.3 1 2 0 0.0005 14 0 0 0 2.01E+06 2.79E+06 - - - 3.2371 0.9998 221125_WJC_METTL3_EV_vs_WT_F05.19185.19185.2 2.39E-05 Jun-36 R.QFLLQQASGLSSPGNNDSK[136.11].Q "sp|Q8IVH2|FOXP4_HUMAN,tr|B7ZBM3|B7ZBM3_HUMAN,tr|A2A312|A2A312_HUMAN" 3 1997.9898 6.44 70089 19185 2 1997.990672 1000.0022 Forkhead box protein P4 OS=Homo sapiens OX=9606 GN=FOXP4 PE=1 SV=1 5.84 3203.9 - 77637.9 - - - 0.4449 - 1.55 0.567 - 69.9 1 2 0 0.0009 19 0 0 0 4.42E+06 6.86E+05 - - - 4.3061 1 221125_WJC_METTL3_EV_vs_WT_F05.19188.19188.3 1.57E-09 15/60 K.K[136.11]VDDDLGTIESLEEAK[136.11].K sp|P35580|MYH10_HUMAN 1 1776.8964 0.79 70090 19188 3 1776.89778 593.3061 Myosin-10 OS=Homo sapiens OX=9606 GN=MYH10 PE=1 SV=3 4.02 3204.3 - 1.04E+06 - - - 0.7823 - 2.986 0.61 - 458.7 1 2 0 0.0014 16 0 0 0 1.14E+07 1.44E+07 - - - 8.1474 0.9743 221125_WJC_METTL3_EV_vs_WT_F05.19189.19189.3 0.144 Nov-64 R.IINEPTAAAIAYGLDK[136.11]K[136.11].G "sp|P54652|HSP72_HUMAN,sp|P11142|HSP7C_HUMAN,tr|E9PKE3|E9PKE3_HUMAN,tr|E9PN89|E9PN89_HUMAN,tr|E9PI65|E9PI65_HUMAN" 5 1803.0113 0.28 70091 19189 3 1803.01384 602.011 Heat shock-related 70 kDa protein 2 OS=Homo sapiens OX=9606 GN=HSPA2 PE=1 SV=1 6.07 3204.4 - 628502 - - - 1.4088 - 1.633 0.16 - 70.6 2 2 0 0.0025 17 0 0 0 2.58E+07 9.29E+07 - - - 1.4228 1 221125_WJC_METTL3_EV_vs_WT_F05.19190.19190.3 9.85E-06 18/40 K.K[136.11]SAEFLLHMLK[136.11].N "sp|P18621|RL17_HUMAN,tr|A0A087WWH0|A0A087WWH0_HUMAN,tr|J3QS96|J3QS96_HUMAN,tr|J3QLC8|J3QLC8_HUMAN,tr|J3QQT2|J3QQT2_HUMAN,tr|A0A087WY81|A0A087WY81_HUMAN,tr|A0A0A0MRF8|A0A0A0MRF8_HUMAN,tr|J3KRB3|J3KRB3_HUMAN,tr|J3KRX5|J3KRX5_HUMAN,tr|A0A087WXM6|A0A087WXM6_HUMAN,tr|A0A0A6YYL6|A0A0A6YYL6_HUMAN" 11 1331.7606 0.94 70092 19190 3 1331.762054 444.9275 60S ribosomal protein L17 OS=Homo sapiens OX=9606 GN=RPL17 PE=1 SV=3 8.6 3204.5 - 839397 - - - 1.07 - 3.246 0.449 - 384.8 1 2 0 0.0014 11 0 0 0 1.31E+07 1.39E+07 - - - 6.8904 0.9999 221125_WJC_METTL3_EV_vs_WT_F05.19191.19191.4 1.73E-08 19/78 K.TLNNKFASFIDKVR.F "sp|Q9NSB2|KRT84_HUMAN,sp|P48668|K2C6C_HUMAN,sp|P05787|K2C8_HUMAN,sp|Q01546|K22O_HUMAN,sp|P12035|K2C3_HUMAN,sp|P04259|K2C6B_HUMAN,sp|P13647|K2C5_HUMAN,sp|P35908|K22E_HUMAN,sp|P08729|K2C7_HUMAN,sp|O95678|K2C75_HUMAN,sp|Q5XKE5|K2C79_HUMAN,sp|P02538|K2C6A_HUMAN,tr|F8VUG2|F8VUG2_HUMAN,tr|F8W0C6|F8W0C6_HUMAN,tr|F8W1U3|F8W1U3_HUMAN" 15 1651.9046 272.43 70093 19191 4 1651.906074 413.9834 "Keratin, type II cuticular Hb4 OS=Homo sapiens OX=9606 GN=KRT84 PE=2 SV=2" 9.99 3204.7 - 589514 - - - 0.8984 - 3.102 0.567 - 330.5 1 2 2 0.0015 14 0 0 0 7.49E+06 2.75E+04 - - - 4.5728 1 221125_WJC_METTL3_EV_vs_WT_F05.19192.19192.2 0.00691 16/26 F.NQGLDC[160.03]DVIVAEVR[166.11].S sp|Q86U44|MTA70_HUMAN 1 1596.7805 0.01 70094 19192 2 1596.783035 799.3975 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 4.03 3204.8 - 415101 - - - 1.5713 - 3.345 0.573 - 1201.5 1 1 0 0.0025 14 0 0 0 6.38E+04 5.51E+06 - - - 6.3025 0.9995 221125_WJC_METTL3_EV_vs_WT_F05.19193.19193.4 0.000491 11/120 R.MPLATSTDHGHNLQTVQLLIK.K "sp|Q01082|SPTB2_HUMAN,tr|A0A087WUZ3|A0A087WUZ3_HUMAN" 2 2316.226 1.5 70095 19193 4 2316.234527 580.0638 "Spectrin beta chain, non-erythrocytic 1 OS=Homo sapiens OX=9606 GN=SPTBN1 PE=1 SV=2" 6.69 3204.9 - 343601 - - - 3.681 - 2.166 0.429 - 65.4 1 2 0 0.0085 21 0 0 0 1.42E+07 9.45E+06 - - - 3.2132 0.9933 221125_WJC_METTL3_EV_vs_WT_F05.19195.19195.3 0.0171 Jul-92 R.GEDEASEPPAGGLHPAPLQLGLGR.E "sp|Q9HCM7|FBSL_HUMAN,tr|A0A3B3IRR3|A0A3B3IRR3_HUMAN,tr|A0A7P0Z485|A0A7P0Z485_HUMAN" 3 2367.1819 1.69 70097 19195 3 2367.186348 790.0679 Fibrosin-1-like protein OS=Homo sapiens OX=9606 GN=FBRSL1 PE=1 SV=4 4.4 3205.2 - 193650 - - - 1.8841 - 1.548 0.257 - 31.2 1 2 0 0.0045 24 0 0 0 3.18E+06 1.89E+06 - - - 2.419 0.9989 221125_WJC_METTL3_EV_vs_WT_F05.19200.19200.3 3.83E-05 22/80 K.EEPPKELPAAEPVLSPLEGTK.M "sp|Q9BY77|PDIP3_HUMAN,tr|F6VRR5|F6VRR5_HUMAN" 2 2230.1733 1.91 70101 19200 3 2230.183135 744.3984 Polymerase delta-interacting protein 3 OS=Homo sapiens OX=9606 GN=POLDIP3 PE=1 SV=2 4.33 3205.9 - 2.57E+06 - - - 4.4189 - 3.288 0.501 - 446.9 1 2 1 0.0099 21 0 0 0 4.99E+07 2.62E+07 - - - 6.9766 0.9989 221125_WJC_METTL3_EV_vs_WT_F05.19201.19201.3 0.000151 15/80 K.EEPPK[136.11]ELPAAEPVLSPLEGTK[136.11].M "sp|Q9BY77|PDIP3_HUMAN,tr|F6VRR5|F6VRR5_HUMAN" 2 2246.2017 1.95 70102 19201 3 2246.205064 749.7412 Polymerase delta-interacting protein 3 OS=Homo sapiens OX=9606 GN=POLDIP3 PE=1 SV=2 4.33 3206 - 1.34E+06 - - - 1.5065 - 2.666 0.345 - 182.9 1 2 1 0.0034 21 0 0 0 1.64E+08 8.41E+07 - - - 4.7364 0.9999 221125_WJC_METTL3_EV_vs_WT_F05.19204.19204.3 1.27E-06 18/64 K.KANLQIDQINTDLNLER.S sp|P35579|MYH9_HUMAN 1 1997.0542 0.98 70105 19204 3 1997.063663 666.692 Myosin-9 OS=Homo sapiens OX=9606 GN=MYH9 PE=1 SV=4 4.56 3206.4 - 368626 - - - 4.7545 - 3.857 0.558 - 562 1 2 0 0.0095 17 0 0 0 1.14E+07 1.16E+07 - - - 8.1687 1 221125_WJC_METTL3_EV_vs_WT_F05.19205.19205.3 3.39E-11 15/96 R.SLLGLDSGELQSGPESSSSPGVHVR[166.11].Q "sp|P49815|TSC2_HUMAN,tr|A0A2R8Y7C8|A0A2R8Y7C8_HUMAN,tr|A0A2R8YDR3|A0A2R8YDR3_HUMAN,tr|A0A2R8Y7X5|A0A2R8Y7X5_HUMAN,tr|A0A2R8YDZ2|A0A2R8YDZ2_HUMAN,tr|A0A2R8YGD6|A0A2R8YGD6_HUMAN,tr|X5D2U8|X5D2U8_HUMAN,tr|A0A2R8Y5F1|A0A2R8Y5F1_HUMAN,tr|A0A2R8YGU4|A0A2R8YGU4_HUMAN,tr|H3BMQ0|H3BMQ0_HUMAN,tr|A0A2R8Y6C9|A0A2R8Y6C9_HUMAN" 11 2504.2382 4.32 70106 19205 3 2504.241335 835.7534 Tuberin OS=Homo sapiens OX=9606 GN=TSC2 PE=1 SV=2 4.65 3206.5 - 361398 - - - 1.2399 - 3.257 0.676 - 148.1 1 2 0 0.0031 25 0 0 0 1.44E+07 3.32E+06 - - - 8.7925 1 221125_WJC_METTL3_EV_vs_WT_F05.19206.19206.3 0.000181 14/52 K.IAILTC[160.03]PFEPPKPK.T "sp|P48643|TCPE_HUMAN,tr|E9PCA1|E9PCA1_HUMAN,tr|B7ZAR1|B7ZAR1_HUMAN,tr|E7ENZ3|E7ENZ3_HUMAN" 4 1609.8902 0.7 70107 19206 3 1609.891676 537.6373 T-complex protein 1 subunit epsilon OS=Homo sapiens OX=9606 GN=CCT5 PE=1 SV=1 8.2 3206.6 - 347420 - - - 0.9255 - 2.578 0.455 - 268.8 1 2 0 0.0015 14 0 0 0 1.53E+07 2.18E+07 - - - 6.1291 1 221125_WJC_METTL3_EV_vs_WT_F05.19207.19207.3 1.26E-05 Oct-80 R.VNFC[160.03]PLPSEQC[160.03]YQAPGGPEDR[166.11].G sp|Q15654|TRIP6_HUMAN 1 2430.0608 0.25 70108 19207 3 2430.058852 811.0275 Thyroid receptor-interacting protein 6 OS=Homo sapiens OX=9606 GN=TRIP6 PE=1 SV=3 4.14 3206.8 - 244071 - - - -0.8016 - 2.393 0.487 - 74.8 1 2 0 -0.0019 21 0 0 0 5.96E+05 2.36E+06 - - - 6.0609 0.9999 221125_WJC_METTL3_EV_vs_WT_F05.19208.19208.3 1.01E-05 Dec-68 R.TVVSGLVNHVPLEQMQNR[166.11].M "sp|Q12904|AIMP1_HUMAN,tr|A0A804HJ47|A0A804HJ47_HUMAN,tr|A0A5F9ZHC5|A0A5F9ZHC5_HUMAN" 3 2030.0607 0.72 70109 19208 3 2030.065638 677.6942 Aminoacyl tRNA synthase complex-interacting multifunctional protein 1 OS=Homo sapiens OX=9606 GN=AIMP1 PE=1 SV=2 6.41 3206.9 - 228496 - - - 2.4502 - 2.259 0.54 - 93.9 1 2 0 0.005 18 0 0 0 1.25E+07 1.73E+07 - - - 6.5883 0.9999 221125_WJC_METTL3_EV_vs_WT_F05.19209.19209.3 7.14E-07 Dec-76 K.SYNPFDDDGEDEGAR[166.11]PAPWR[166.11].D sp|O95721|SNP29_HUMAN 1 2312.9837 2.71 70110 19209 3 2312.99268 772.0019 Synaptosomal-associated protein 29 OS=Homo sapiens OX=9606 GN=SNAP29 PE=1 SV=1 3.96 3207 - 179537 - - - 3.8638 - 2.402 0.642 - 125.4 1 2 0 0.0089 20 0 0 0 2.39E+07 8.83E+06 - - - 7.8211 1 221125_WJC_METTL3_EV_vs_WT_F05.19214.19214.3 9.98E-10 25/52 R.K[136.11]TVTAMDVVYALK[136.11]R[166.11].Q sp|P62805|H4_HUMAN 1 1619.9279 0.81 70113 19214 3 1619.930027 540.9832 Histone H4 OS=Homo sapiens OX=9606 GN=H4C1 PE=1 SV=2 9.7 3207.7 - 1.04E+06 - - - 1.3013 - 4.48 0.603 - 850.4 1 2 0 0.0021 14 0 0 0 9.34E+06 1.15E+07 - - - 9.2476 1 221125_WJC_METTL3_EV_vs_WT_F05.19215.19215.3 2.57E-07 14/76 K.SYNPFDDDGEDEGARPAPWR.D sp|O95721|SNP29_HUMAN 1 2292.9672 2.71 70114 19215 3 2292.970442 765.3297 Synaptosomal-associated protein 29 OS=Homo sapiens OX=9606 GN=SNAP29 PE=1 SV=1 3.96 3207.8 - 767744 - - - 1.4126 - 2.582 0.659 - 203.6 1 2 0 0.0032 20 0 0 0 2.39E+07 8.83E+06 - - - 8.1875 1 221125_WJC_METTL3_EV_vs_WT_F05.19218.19218.2 1.95E-10 30-Nov K.VELAQLQEEWNEHNAK.L sp|Q9H307|PININ_HUMAN 1 1936.9279 7.91 70117 19218 2 1936.932705 969.4712 Pinin OS=Homo sapiens OX=9606 GN=PNN PE=1 SV=5 4.48 3208.2 - 172034 - - - 2.4782 - 2.89 0.662 - 270.4 1 2 0 0.0048 16 0 0 0 2.63E+06 3.33E+05 - - - 6.5382 0.999 221125_WJC_METTL3_EV_vs_WT_F05.19221.19221.3 4.50E-07 14/76 K.GILGYTEHQVVSSDFNSDTH.S "sp|P04406|G3P_HUMAN,tr|E7EUT5|E7EUT5_HUMAN" 2 2204.9974 - 70119 19221 3 2204.996704 736.0064 Glyceraldehyde-3-phosphate dehydrogenase OS=Homo sapiens OX=9606 GN=GAPDH PE=1 SV=3 4.52 3208.6 - 342042 - - - -0.3342 - 3.062 0.647 - 259.1 1 1 0 -0.0007 20 0 0 0 - - - - - 8.4681 0.9999 221125_WJC_METTL3_EV_vs_WT_F05.19226.19226.3 9.80E-08 18/64 K.EAFSLFDKDGDGTITTK.E "sp|P0DP25|CALM3_HUMAN,sp|P0DP23|CALM1_HUMAN,sp|P0DP24|CALM2_HUMAN,tr|F8WBR5|F8WBR5_HUMAN,tr|G3V479|G3V479_HUMAN,tr|M0QZ52|M0QZ52_HUMAN,tr|E7EMB3|E7EMB3_HUMAN" 7 1843.884 1 70123 19226 3 1843.886398 615.6353 Calmodulin-3 OS=Homo sapiens OX=9606 GN=CALM3 PE=1 SV=1 4.23 3209.1 - 829707 - - - 1.3146 - 3.364 0.585 - 570.4 1 2 1 0.0024 17 0 0 0 9.60E+07 9.63E+07 - - - 8.1262 0.8757 221125_WJC_METTL3_EV_vs_WT_F05.19230.19230.3 0.000146 Sep-76 M.R[166.11]ILSAENIPNLPPGGGLAGK[136.11].R "sp|O75688|PPM1B_HUMAN,tr|B8ZZF0|B8ZZF0_HUMAN,tr|A0A3B3IS24|A0A3B3IS24_HUMAN,tr|C9JIR6|C9JIR6_HUMAN" 4 1991.1283 4.68 70127 19230 3 1991.12759 664.7167 Protein phosphatase 1B OS=Homo sapiens OX=9606 GN=PPM1B PE=1 SV=1 8.75 3209.6 - 196379 - - - -0.3465 - 2.096 0.248 - 70.7 1 1 0 -0.0007 20 0 0 0 1.56E+07 3.34E+06 - - - 3.1001 0.9999 221125_WJC_METTL3_EV_vs_WT_F05.19236.19236.3 2.13E-07 19/72 K.ASEKDIAPPPEEC[160.03]LQLLSR.A "sp|Q99567|NUP88_HUMAN,tr|I3L4K7|I3L4K7_HUMAN,tr|J3KMX1|J3KMX1_HUMAN" 3 2152.0834 3.48 70131 19236 3 2152.084785 718.3684 Nuclear pore complex protein Nup88 OS=Homo sapiens OX=9606 GN=NUP88 PE=1 SV=2 4.41 3210.3 - 501894 - - - 0.6347 - 3.704 0.563 - 429.1 1 2 1 0.0014 19 0 0 0 7.90E+06 2.27E+06 - - - 8.0335 0.999 221125_WJC_METTL3_EV_vs_WT_F05.19239.19239.4 0.0147 9/102 K.QQAHDLLINK[136.11]PDGTFLLR[166.11].F "sp|P51692|STA5B_HUMAN,sp|P42229|STA5A_HUMAN,tr|A0A7I2YQY3|A0A7I2YQY3_HUMAN,tr|K7EIF9|K7EIF9_HUMAN,tr|K7EK35|K7EK35_HUMAN,tr|A0A7I2V380|A0A7I2V380_HUMAN,tr|A0A7I2YQF1|A0A7I2YQF1_HUMAN" 7 2096.1497 0.05 70134 19239 4 2096.150381 525.0447 Signal transducer and activator of transcription 5B OS=Homo sapiens OX=9606 GN=STAT5B PE=1 SV=2 6.75 3210.7 - 379608 - - - 0.3044 - 1.754 0.304 - 53.7 1 2 0 0.0006 18 0 0 0 4.34E+05 8.95E+06 - - - 2.0643 0.9939 221125_WJC_METTL3_EV_vs_WT_F05.19240.19240.4 0.000138 Oct-84 Q.FVLSDEFSHLR[166.11]PEQR[166.11].L sp|Q9UQE7|SMC3_HUMAN 1 1878.9491 1.01 70135 19240 4 1878.950553 470.7446 Structural maintenance of chromosomes protein 3 OS=Homo sapiens OX=9606 GN=SMC3 PE=1 SV=2 5.45 3210.8 - 267202 - - - 0.7541 - 2.281 0.472 - 84.9 1 1 0 0.0014 15 0 0 0 6.45E+06 6.41E+06 - - - 3.629 1 221125_WJC_METTL3_EV_vs_WT_F05.19244.19244.3 2.15E-05 Dec-84 R.QWVDTDDTSSENTVVPPETYVK[136.11].V "sp|P15927|RFA2_HUMAN,tr|Q5TEJ7|Q5TEJ7_HUMAN" 2 2517.1638 1.42 70137 19244 3 2517.163524 840.0619 Replication protein A 32 kDa subunit OS=Homo sapiens OX=9606 GN=RPA2 PE=1 SV=1 3.77 3211.4 - 644361 - - - -0.1271 - 2.229 0.516 - 80.7 1 2 0 -0.0003 22 0 0 0 6.42E+07 4.52E+07 - - - 6.1931 0.9998 221125_WJC_METTL3_EV_vs_WT_F05.19245.19245.3 2.26E-08 17/44 R.NMQDLVEDLKNK.Y "sp|P48668|K2C6C_HUMAN,sp|P04259|K2C6B_HUMAN" 2 1445.7184 708.08 70138 19245 3 1445.722525 482.9134 "Keratin, type II cytoskeletal 6C OS=Homo sapiens OX=9606 GN=KRT6C PE=1 SV=3" 4.56 3211.5 - 766418 - - - 2.8332 - 3.188 0.586 - 529.9 1 2 1 0.0041 12 0 0 0 1.77E+08 2.50E+05 - - - 8.2859 1 221125_WJC_METTL3_EV_vs_WT_F05.19246.19246.3 4.70E-06 Dec-84 R.QWVDTDDTSSENTVVPPETYVK.V "sp|P15927|RFA2_HUMAN,tr|Q5TEJ7|Q5TEJ7_HUMAN" 2 2509.1496 1.38 70139 19246 3 2509.14862 837.3905 Replication protein A 32 kDa subunit OS=Homo sapiens OX=9606 GN=RPA2 PE=1 SV=1 3.77 3211.6 - 936829 - - - -0.4081 - 2.298 0.543 - 55.6 1 2 0 -0.001 22 0 0 0 7.13E+07 5.18E+07 - - - 6.5663 1 221125_WJC_METTL3_EV_vs_WT_F05.19247.19247.2 6.02E-09 13/28 R.ELAQQVQQVADDYGK.C "sp|Q92841|DDX17_HUMAN,tr|A0A5H1ZRQ2|A0A5H1ZRQ2_HUMAN,tr|A0A1X7SBZ2|A0A1X7SBZ2_HUMAN" 3 1690.8162 1.11 70140 19247 2 1690.816696 846.4154 Probable ATP-dependent RNA helicase DDX17 OS=Homo sapiens OX=9606 GN=DDX17 PE=1 SV=2 4.03 3211.7 - 558461 - - - 0.2762 - 2.907 0.586 - 735.4 1 2 0 0.0005 15 0 0 0 1.05E+07 9.42E+06 - - - 5.9926 0.9983 221125_WJC_METTL3_EV_vs_WT_F05.19248.19248.2 1.20E-05 24-Oct K.SDNK[136.11]DDDIDIDAI.- sp|P55010|IF5_HUMAN 1 1455.6456 1.02 70141 19248 2 1455.645438 728.8301 Eukaryotic translation initiation factor 5 OS=Homo sapiens OX=9606 GN=EIF5 PE=1 SV=2 3.57 3211.9 - 520575 - - - -0.1443 - 2.222 0.462 - 370.6 1 2 1 -0.0002 13 0 0 0 1.09E+07 1.08E+07 - - - 4.5024 0.9612 221125_WJC_METTL3_EV_vs_WT_F05.19252.19252.4 0.018 Oct-84 Q.FVLSDEFSHLRPEQR.L sp|Q9UQE7|SMC3_HUMAN 1 1858.9326 1.01 70145 19252 4 1858.933632 465.7404 Structural maintenance of chromosomes protein 3 OS=Homo sapiens OX=9606 GN=SMC3 PE=1 SV=2 5.45 3212.4 - 205238 - - - 0.5573 - 2.091 0.351 - 95.9 1 1 0 0.001 15 0 0 0 6.48E+06 6.41E+06 - - - 2.5448 0.9999 221125_WJC_METTL3_EV_vs_WT_F05.19258.19258.2 2.31E-05 16/28 R.ELAQQVQQVADDYGK[136.11].C "sp|Q92841|DDX17_HUMAN,tr|A0A5H1ZRQ2|A0A5H1ZRQ2_HUMAN,tr|A0A1X7SBZ2|A0A1X7SBZ2_HUMAN" 3 1698.8304 1.11 70149 19258 2 1698.830986 850.4225 Probable ATP-dependent RNA helicase DDX17 OS=Homo sapiens OX=9606 GN=DDX17 PE=1 SV=2 4.03 3213.1 - 549541 - - - 0.3279 - 3.179 0.514 - 1045.2 1 2 0 0.0006 15 0 0 0 1.05E+07 9.42E+06 - - - 5.6807 0.9914 221125_WJC_METTL3_EV_vs_WT_F05.19260.19260.3 0.000113 Nov-68 R.TVVSGLVNHVPLEQMQNR.M "sp|Q12904|AIMP1_HUMAN,tr|A0A804HJ47|A0A804HJ47_HUMAN,tr|A0A5F9ZHC5|A0A5F9ZHC5_HUMAN" 3 2020.0524 0.72 70151 19260 3 2020.067119 674.3581 Aminoacyl tRNA synthase complex-interacting multifunctional protein 1 OS=Homo sapiens OX=9606 GN=AIMP1 PE=1 SV=2 6.41 3213.3 - 1.10E+06 - - - 7.2894 - 2.016 0.419 - 79.3 1 2 0 0.0147 18 0 0 0 1.23E+07 1.69E+07 - - - 4.9532 1 221125_WJC_METTL3_EV_vs_WT_F05.19261.19261.3 1.46E-10 22/76 K.GLSEDTTEETLK[136.11]ESFDGSVR[166.11].A "sp|P19338|NUCL_HUMAN,tr|A0A7I2V699|A0A7I2V699_HUMAN,tr|A0A7I2V2U7|A0A7I2V2U7_HUMAN,tr|A0A7I2V3F3|A0A7I2V3F3_HUMAN,tr|A0A7I2V428|A0A7I2V428_HUMAN,tr|H7BY16|H7BY16_HUMAN,tr|A0A7I2V5M5|A0A7I2V5M5_HUMAN,tr|C9JLB1|C9JLB1_HUMAN" 8 2217.0404 1.04 70152 19261 3 2217.041645 740.0207 Nucleolin OS=Homo sapiens OX=9606 GN=NCL PE=1 SV=3 4.08 3213.4 - 797866 - - - 0.5742 - 4.365 0.623 - 763 1 2 1 0.0013 20 0 0 0 1.49E+08 1.43E+08 - - - 9.0605 0.9967 221125_WJC_METTL3_EV_vs_WT_F05.19264.19264.3 0.000135 13/48 S.SHNLQSIFNIGSR.G "sp|P43243|MATR3_HUMAN,tr|A8MXP9|A8MXP9_HUMAN,tr|D6R991|D6R991_HUMAN,tr|D6REK4|D6REK4_HUMAN,tr|A0A0R4J2E8|A0A0R4J2E8_HUMAN,tr|D6RCM3|D6RCM3_HUMAN,tr|D6R8Z5|D6R8Z5_HUMAN,tr|D6REM6|D6REM6_HUMAN" 8 1471.7532 1.32 70155 19264 3 1471.754959 491.5917 Matrin-3 OS=Homo sapiens OX=9606 GN=MATR3 PE=1 SV=2 9.49 3213.8 - 208182 - - - 1.2122 - 2.591 0.501 - 280.2 1 1 0 0.0018 13 0 0 0 2.72E+08 2.06E+08 - - - 6.7064 1 221125_WJC_METTL3_EV_vs_WT_F05.19265.19265.3 4.26E-05 Aug-44 K.SFFDNISC[160.03]DDNR.E "sp|Q8ND56|LS14A_HUMAN,tr|A0A096LP11|A0A096LP11_HUMAN,tr|A0A140TA76|A0A140TA76_HUMAN,tr|A0A0G2JQ95|A0A0G2JQ95_HUMAN" 4 1488.594 1.12 70156 19265 3 1488.595233 497.2053 Protein LSM14 homolog A OS=Homo sapiens OX=9606 GN=LSM14A PE=1 SV=3 3.93 3213.9 - 194215 - - - 0.8572 - 1.67 0.566 - 107.5 1 2 0 0.0013 12 0 0 0 5.27E+06 4.71E+06 - - - 6.2715 0.9996 221125_WJC_METTL3_EV_vs_WT_F05.19269.19269.4 0.000687 Sep-78 R.KTVTAMDVVYALKR.Q sp|P62805|H4_HUMAN 1 1593.8912 0.83 70159 19269 4 1593.894657 399.4801 Histone H4 OS=Homo sapiens OX=9606 GN=H4C1 PE=1 SV=2 9.7 3214.4 - 115523 - - - 2.1382 - 1.882 0.372 - 87.5 1 2 0 0.0034 14 0 0 0 6.27E+06 7.59E+06 - - - 2.6931 0.9961 221125_WJC_METTL3_EV_vs_WT_F05.19271.19271.2 0.0102 24-Aug K.SDNKDDDIDIDAI.- sp|P55010|IF5_HUMAN 1 1447.6314 1.02 70160 19271 2 1447.631878 724.823 Eukaryotic translation initiation factor 5 OS=Homo sapiens OX=9606 GN=EIF5 PE=1 SV=2 3.57 3214.6 - 892784 - - - 0.297 - 1.677 0.415 - 210.7 1 2 1 0.0004 13 0 0 0 1.09E+07 1.08E+07 - - - 3.433 0.9987 221125_WJC_METTL3_EV_vs_WT_F05.19272.19272.3 1.91E-09 14/48 S.SHNLQSIFNIGSR[166.11].G "sp|P43243|MATR3_HUMAN,tr|A8MXP9|A8MXP9_HUMAN,tr|D6R991|D6R991_HUMAN,tr|D6REK4|D6REK4_HUMAN,tr|A0A0R4J2E8|A0A0R4J2E8_HUMAN,tr|D6RCM3|D6RCM3_HUMAN,tr|D6R8Z5|D6R8Z5_HUMAN,tr|D6REM6|D6REM6_HUMAN" 8 1481.7614 1.32 70161 19272 3 1481.761609 494.9278 Matrin-3 OS=Homo sapiens OX=9606 GN=MATR3 PE=1 SV=2 9.49 3214.8 - 669384 - - - 0.1107 - 2.805 0.589 - 286.5 1 1 0 0.0002 13 0 0 0 2.72E+08 2.06E+08 - - - 7.9032 1 221125_WJC_METTL3_EV_vs_WT_F05.19273.19273.3 7.86E-11 17/68 K.RSAELPDAVGPIVQLQEK.L "sp|Q96PU8|QKI_HUMAN,tr|F5H5U6|F5H5U6_HUMAN,tr|F5GYM3|F5GYM3_HUMAN,tr|F5GXS8|F5GXS8_HUMAN,tr|F5GYT7|F5GYT7_HUMAN,tr|F5H8C8|F5H8C8_HUMAN,tr|H0YG47|H0YG47_HUMAN" 7 1949.0582 2.37 70162 19273 3 1949.0596 650.6933 Protein quaking OS=Homo sapiens OX=9606 GN=QKI PE=1 SV=1 4.68 3214.9 - 1.05E+06 - - - 0.7229 - 3.312 0.591 - 362.5 1 2 0 0.0014 18 0 0 0 5.41E+07 2.29E+07 - - - 8.1107 0.9996 221125_WJC_METTL3_EV_vs_WT_F05.19275.19275.3 0.000133 Oct-60 R.AKFEEYGPVIEC[160.03]DIVK.D "sp|Q9BWF3|RBM4_HUMAN,sp|Q9BQ04|RBM4B_HUMAN,tr|E9PM61|E9PM61_HUMAN,tr|D6R9K7|D6R9K7_HUMAN,tr|J3QRR5|J3QRR5_HUMAN,tr|E9PB51|E9PB51_HUMAN,tr|U3KQD5|U3KQD5_HUMAN,tr|E9PLB0|E9PLB0_HUMAN" 8 1895.9339 1.99 70164 19275 3 1895.929813 632.9852 RNA-binding protein 4 OS=Homo sapiens OX=9606 GN=RBM4 PE=1 SV=1 4.41 3215.1 - 580164 - - - -2.1567 - 2.248 0.496 - 155.3 1 2 1 -0.0041 16 0 0 0 1.30E+07 6.52E+06 - - - 6.1472 1 221125_WJC_METTL3_EV_vs_WT_F05.19276.19276.2 1.45E-09 14/32 K.EAFSLFDKDGDGTITTK.E "sp|P0DP25|CALM3_HUMAN,sp|P0DP23|CALM1_HUMAN,sp|P0DP24|CALM2_HUMAN,tr|F8WBR5|F8WBR5_HUMAN,tr|G3V479|G3V479_HUMAN,tr|M0QZ52|M0QZ52_HUMAN,tr|E7EMB3|E7EMB3_HUMAN" 7 1843.884 0.45 70165 19276 2 1843.887682 922.9493 Calmodulin-3 OS=Homo sapiens OX=9606 GN=CALM3 PE=1 SV=1 4.23 3215.3 - 254493 - - - 2.011 - 3.126 0.629 - 596.7 1 2 1 0.0037 17 0 0 0 2.83E+06 6.34E+06 - - - 6.4878 1 221125_WJC_METTL3_EV_vs_WT_F05.19278.19278.2 1.38E-09 Dec-32 R.SVGDGETVEFDVVEGEK[136.11].G "sp|Q9Y2T7|YBOX2_HUMAN,sp|P67809|YBOX1_HUMAN,sp|P16989|YBOX3_HUMAN,tr|H0Y449|H0Y449_HUMAN,tr|A0A0D9SEI8|A0A0D9SEI8_HUMAN" 5 1802.8302 0.61 70167 19278 2 1802.830064 902.4224 Y-box-binding protein 2 OS=Homo sapiens OX=9606 GN=YBX2 PE=1 SV=2 3.77 3215.5 - 203232 - - - -0.0499 - 2.554 0.666 - 321.1 1 2 0 -0.0001 17 0 0 0 1.30E+06 2.11E+06 - - - 6.2653 1 221125_WJC_METTL3_EV_vs_WT_F05.19283.19283.3 3.02E-10 23/76 K.GLSEDTTEETLKESFDGSVR.A "sp|P19338|NUCL_HUMAN,tr|A0A7I2V699|A0A7I2V699_HUMAN,tr|A0A7I2V2U7|A0A7I2V2U7_HUMAN,tr|A0A7I2V3F3|A0A7I2V3F3_HUMAN,tr|A0A7I2V428|A0A7I2V428_HUMAN,tr|H7BY16|H7BY16_HUMAN,tr|A0A7I2V5M5|A0A7I2V5M5_HUMAN,tr|C9JLB1|C9JLB1_HUMAN" 8 2199.0179 1.04 70170 19283 3 2199.019649 734.0132 Nucleolin OS=Homo sapiens OX=9606 GN=NCL PE=1 SV=3 4.08 3216.1 - 4.32E+06 - - - 0.7944 - 4.208 0.662 - 767.1 1 2 1 0.0017 20 0 0 0 1.49E+08 1.43E+08 - - - 9.4063 0.9999 221125_WJC_METTL3_EV_vs_WT_F05.19289.19289.4 1.72E-05 13/78 R.VHFEESSK[136.11]LEDLLR[166.11].K "sp|P12956|XRCC6_HUMAN,tr|B1AHC9|B1AHC9_HUMAN" 2 1718.8958 1.13 70176 19289 4 1718.896726 430.7312 X-ray repair cross-complementing protein 6 OS=Homo sapiens OX=9606 GN=XRCC6 PE=1 SV=2 4.83 3216.9 - 329681 - - - 0.5271 - 2.793 0.528 - 216.3 1 2 1 0.0009 14 0 0 0 1.32E+07 1.17E+07 - - - 4.1953 1 221125_WJC_METTL3_EV_vs_WT_F05.19290.19290.2 1.61E-07 14/36 R.AGDWQC[160.03]PNPGC[160.03]GNQNFAWR[166.11].T "sp|Q01844|EWS_HUMAN,tr|B0QYK0|B0QYK0_HUMAN,tr|A0A0D9SFL3|A0A0D9SFL3_HUMAN,tr|C9JGE3|C9JGE3_HUMAN" 4 2243.9253 0.86 70177 19290 2 2243.926352 1122.9699 RNA-binding protein EWS OS=Homo sapiens OX=9606 GN=EWSR1 PE=1 SV=1 5.86 3217 - 326562 - - - 0.4644 - 3.496 0.772 - 376.9 1 2 0 0.001 19 0 0 0 1.58E+07 1.84E+07 - - - 7.8198 0.9969 221125_WJC_METTL3_EV_vs_WT_F05.19291.19291.3 0.00791 Aug-68 K.QQAHDLLINK[136.11]PDGTFLLR[166.11].F "sp|P51692|STA5B_HUMAN,sp|P42229|STA5A_HUMAN,tr|A0A7I2YQY3|A0A7I2YQY3_HUMAN,tr|K7EIF9|K7EIF9_HUMAN,tr|K7EK35|K7EK35_HUMAN,tr|A0A7I2V380|A0A7I2V380_HUMAN,tr|A0A7I2YQF1|A0A7I2YQF1_HUMAN" 7 2096.1497 0.02 70178 19291 3 2096.154408 699.7239 Signal transducer and activator of transcription 5B OS=Homo sapiens OX=9606 GN=STAT5B PE=1 SV=2 6.75 3217.1 - 276357 - - - 2.2255 - 1.664 0.294 - 60.4 1 2 0 0.0047 18 0 0 0 4.60E+04 2.11E+06 - - - 3.0845 0.9999 221125_WJC_METTL3_EV_vs_WT_F05.19292.19292.4 2.95E-06 14/78 R.VHFEESSKLEDLLR.K "sp|P12956|XRCC6_HUMAN,tr|B1AHC9|B1AHC9_HUMAN" 2 1700.8734 1.13 70179 19292 4 1700.874486 426.2256 X-ray repair cross-complementing protein 6 OS=Homo sapiens OX=9606 GN=XRCC6 PE=1 SV=2 4.83 3217.3 - 267596 - - - 0.6679 - 2.842 0.586 - 216.8 1 2 1 0.0011 14 0 0 0 1.32E+07 1.17E+07 - - - 4.7064 1 221125_WJC_METTL3_EV_vs_WT_F05.19295.19295.3 8.29E-11 15/76 R.C[160.03]EHDGVMTGANGEVSFINIK[136.11].T sp|O15371|EIF3D_HUMAN 1 2185.0023 1.44 70180 19295 3 2185.001123 729.3414 Eukaryotic translation initiation factor 3 subunit D OS=Homo sapiens OX=9606 GN=EIF3D PE=1 SV=1 4.65 3217.7 - 785922 - - - -0.5565 - 3.536 0.646 - 278.9 1 2 0 -0.0012 20 0 0 0 8.27E+06 5.76E+06 - - - 8.806 1 221125_WJC_METTL3_EV_vs_WT_F05.19296.19296.3 6.35E-08 19/52 R.VHFEESSK[136.11]LEDLLR[166.11].K "sp|P12956|XRCC6_HUMAN,tr|B1AHC9|B1AHC9_HUMAN" 2 1718.8958 0.94 70181 19296 3 1718.893647 573.9725 X-ray repair cross-complementing protein 6 OS=Homo sapiens OX=9606 GN=XRCC6 PE=1 SV=2 4.83 3217.8 - 805317 - - - -1.2642 - 3.402 0.606 - 631.9 1 2 1 -0.0022 14 0 0 0 1.55E+07 1.65E+07 - - - 8.5495 1 221125_WJC_METTL3_EV_vs_WT_F05.19297.19297.3 1.32E-06 Dec-52 R.STYNHLSSWLTDAR[166.11].N "sp|P61106|RAB14_HUMAN,tr|X6RFL8|X6RFL8_HUMAN" 2 1659.7881 1.17 70182 19297 3 1659.786083 554.27 Ras-related protein Rab-14 OS=Homo sapiens OX=9606 GN=RAB14 PE=1 SV=4 6.46 3217.9 - 533681 - - - -1.1875 - 2.667 0.477 - 172.7 1 2 0 -0.002 14 0 0 0 6.14E+06 5.26E+06 - - - 6.4645 1 221125_WJC_METTL3_EV_vs_WT_F05.19298.19298.2 9.88E-09 15/36 R.AGDWQC[160.03]PNPGC[160.03]GNQNFAWR.T "sp|Q01844|EWS_HUMAN,tr|B0QYK0|B0QYK0_HUMAN,tr|A0A0D9SFL3|A0A0D9SFL3_HUMAN,tr|C9JGE3|C9JGE3_HUMAN" 4 2233.917 0.86 70183 19298 2 2233.918574 1117.9658 RNA-binding protein EWS OS=Homo sapiens OX=9606 GN=EWSR1 PE=1 SV=1 5.86 3218.1 - 485275 - - - 0.6867 - 3.48 0.727 - 459.6 1 2 0 0.0015 19 0 0 0 1.58E+07 1.84E+07 - - - 7.476 0.9999 221125_WJC_METTL3_EV_vs_WT_F05.19300.19300.4 4.18E-06 13/102 K.YVATLGVEVHPLVFHTNR.G "sp|P62826|RAN_HUMAN,tr|H0YFC6|H0YFC6_HUMAN,tr|B5MDF5|B5MDF5_HUMAN,tr|J3KQE5|J3KQE5_HUMAN,tr|F5H018|F5H018_HUMAN" 5 2051.0952 0.72 70185 19300 4 2051.098702 513.7811 GTP-binding nuclear protein Ran OS=Homo sapiens OX=9606 GN=RAN PE=1 SV=3 6.92 3218.3 - 272482 - - - 1.6854 - 2.74 0.436 - 84.6 1 2 0 0.0035 18 0 0 0 3.66E+06 5.07E+06 - - - 3.3653 0.9999 221125_WJC_METTL3_EV_vs_WT_F05.19302.19302.3 7.42E-07 17/64 K.EAFSLFDK[136.11]DGDGTITTK[136.11].E "sp|P0DP25|CALM3_HUMAN,sp|P0DP23|CALM1_HUMAN,sp|P0DP24|CALM2_HUMAN,tr|F8WBR5|F8WBR5_HUMAN,tr|G3V479|G3V479_HUMAN,tr|M0QZ52|M0QZ52_HUMAN,tr|E7EMB3|E7EMB3_HUMAN" 7 1859.9124 1 70186 19302 3 1859.914094 620.9781 Calmodulin-3 OS=Homo sapiens OX=9606 GN=CALM3 PE=1 SV=1 4.23 3218.5 - 2.88E+06 - - - 0.9248 - 3.299 0.532 - 526.3 1 2 1 0.0017 17 0 0 0 9.60E+07 9.64E+07 - - - 7.4862 1 221125_WJC_METTL3_EV_vs_WT_F05.19304.19304.3 9.64E-13 21/72 R.AGDWQC[160.03]PNPGC[160.03]GNQNFAWR.T "sp|Q01844|EWS_HUMAN,tr|B0QYK0|B0QYK0_HUMAN,tr|A0A0D9SFL3|A0A0D9SFL3_HUMAN,tr|C9JGE3|C9JGE3_HUMAN" 4 2233.917 0.79 70187 19304 3 2233.919787 745.6463 RNA-binding protein EWS OS=Homo sapiens OX=9606 GN=EWSR1 PE=1 SV=1 5.86 3218.8 - 6.03E+06 - - - 1.2297 - 3.94 0.649 - 571.8 1 2 0 0.0027 19 0 0 0 1.11E+08 1.41E+08 - - - 9.1437 1 221125_WJC_METTL3_EV_vs_WT_F05.19305.19305.3 2.16E-09 19/68 K.R[166.11]SAELPDAVGPIVQLQEK[136.11].L "sp|Q96PU8|QKI_HUMAN,tr|F5H5U6|F5H5U6_HUMAN,tr|F5GYM3|F5GYM3_HUMAN,tr|F5GXS8|F5GXS8_HUMAN,tr|F5GYT7|F5GYT7_HUMAN,tr|F5H8C8|F5H8C8_HUMAN,tr|H0YG47|H0YG47_HUMAN" 7 1967.0807 2.38 70188 19305 3 1967.081015 656.7008 Protein quaking OS=Homo sapiens OX=9606 GN=QKI PE=1 SV=1 4.68 3218.9 - 874972 - - - 0.18 - 3.82 0.636 - 539.5 1 2 0 0.0004 18 0 0 0 5.41E+07 2.27E+07 - - - 8.968 1 221125_WJC_METTL3_EV_vs_WT_F05.19306.19306.2 1.54E-08 18/34 L.STPDAPATQDGVESLLQK[136.11].F "sp|Q86U44|MTA70_HUMAN,tr|B4E349|B4E349_HUMAN,tr|F5H6D8|F5H6D8_HUMAN,tr|H0YFV6|H0YFV6_HUMAN,tr|B4DTN4|B4DTN4_HUMAN" 5 1863.9305 0.02 70189 19306 2 1863.928245 932.9725 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 4.03 3219 - 1.29E+06 - - - -1.2297 - 3.337 0.619 - 692.6 1 1 0 -0.0023 18 0 0 0 5.35E+06 2.72E+08 - - - 6.5749 1 221125_WJC_METTL3_EV_vs_WT_F05.19307.19307.3 1.54E-06 19/52 R.VHFEESSKLEDLLR.K "sp|P12956|XRCC6_HUMAN,tr|B1AHC9|B1AHC9_HUMAN" 2 1700.8734 0.94 70190 19307 3 1700.87742 567.9651 X-ray repair cross-complementing protein 6 OS=Homo sapiens OX=9606 GN=XRCC6 PE=1 SV=2 4.83 3219.1 - 879345 - - - 2.3929 - 3.511 0.618 - 543.5 1 2 1 0.0041 14 0 0 0 1.55E+07 1.65E+07 - - - 8.7666 1 221125_WJC_METTL3_EV_vs_WT_F05.19308.19308.3 1.20E-07 14/52 R.STYNHLSSWLTDAR.N "sp|P61106|RAB14_HUMAN,tr|X6RFL8|X6RFL8_HUMAN" 2 1649.7798 1.17 70191 19308 3 1649.78245 550.9339 Ras-related protein Rab-14 OS=Homo sapiens OX=9606 GN=RAB14 PE=1 SV=4 6.46 3219.2 - 654651 - - - 1.616 - 2.871 0.505 - 235.7 1 2 0 0.0027 14 0 0 0 6.14E+06 5.26E+06 - - - 6.9723 0.9997 221125_WJC_METTL3_EV_vs_WT_F05.19311.19311.2 1.52E-06 Aug-42 R.QWVDTDDTSSENTVVPPETYVK[136.11].V "sp|P15927|RFA2_HUMAN,tr|Q5TEJ7|Q5TEJ7_HUMAN" 2 2517.1638 1.64 70194 19311 2 2517.159277 1259.5892 Replication protein A 32 kDa subunit OS=Homo sapiens OX=9606 GN=RPA2 PE=1 SV=1 3.77 3219.6 - 228795 - - - -1.8143 - 1.647 0.563 - 63 1 2 0 -0.0046 22 0 0 0 6.18E+06 3.77E+06 - - - 4.4246 0.9997 221125_WJC_METTL3_EV_vs_WT_F05.19314.19314.3 0.00398 Sep-44 K.K[136.11]SDSNPLTEILK[136.11].C sp|Q96I25|SPF45_HUMAN 1 1359.758 1.27 70197 19314 3 1359.756272 454.26 Splicing factor 45 OS=Homo sapiens OX=9606 GN=RBM17 PE=1 SV=1 6.07 3220 - 145343 - - - -1.3046 - 1.923 0.351 - 170.6 1 2 0 -0.0018 12 0 0 0 9.39E+06 7.39E+06 - - - 4.2653 1 221125_WJC_METTL3_EV_vs_WT_F05.19316.19316.3 3.53E-08 18/68 R.RAEDGSVIDYELIDQDAR.D "sp|P07355|ANXA2_HUMAN,tr|H0YL33|H0YL33_HUMAN,tr|H0YMU9|H0YMU9_HUMAN,tr|H0YNA0|H0YNA0_HUMAN,tr|H0YM50|H0YM50_HUMAN,tr|H0YMD0|H0YMD0_HUMAN,tr|H0YMW4|H0YMW4_HUMAN,tr|H0YN42|H0YN42_HUMAN,tr|H0YN28|H0YN28_HUMAN,tr|H0YNP5|H0YNP5_HUMAN" 10 2063.976 15.29 70198 19316 3 2063.978988 688.9993 Annexin A2 OS=Homo sapiens OX=9606 GN=ANXA2 PE=1 SV=2 3.96 3220.2 - 354402 - - - 1.4588 - 4.038 0.667 - 620.9 1 2 0 0.003 18 0 0 0 1.75E+07 1.15E+06 - - - 9.4511 0.9999 221125_WJC_METTL3_EV_vs_WT_F05.19318.19318.4 8.13E-05 13/102 K.YVATLGVEVHPLVFHTNR[166.11].G "sp|P62826|RAN_HUMAN,tr|H0YFC6|H0YFC6_HUMAN,tr|B5MDF5|B5MDF5_HUMAN,tr|J3KQE5|J3KQE5_HUMAN,tr|F5H018|F5H018_HUMAN" 5 2061.1035 0.77 70199 19318 4 2061.101595 516.2832 GTP-binding nuclear protein Ran OS=Homo sapiens OX=9606 GN=RAN PE=1 SV=3 6.92 3220.6 - 362246 - - - -0.9315 - 2.536 0.401 - 112.2 1 2 0 -0.0019 18 0 0 0 3.66E+06 4.76E+06 - - - 3.0346 1 221125_WJC_METTL3_EV_vs_WT_F05.19319.19319.3 2.70E-08 17/76 R.C[160.03]EHDGVMTGANGEVSFINIK.T sp|O15371|EIF3D_HUMAN 1 2176.9881 1.46 70200 19319 3 2176.97557 726.67 Eukaryotic translation initiation factor 3 subunit D OS=Homo sapiens OX=9606 GN=EIF3D PE=1 SV=1 4.65 3220.7 - 457378 - - - -5.7736 - 3.106 0.651 - 389.5 1 2 0 -0.0126 20 0 0 0 8.33E+06 5.70E+06 - - - 8.544 1 221125_WJC_METTL3_EV_vs_WT_F05.19320.19320.3 3.15E-07 14/64 R.GAPPSSNIEDFHGLLPK[136.11].G "sp|P43243|MATR3_HUMAN,tr|A8MXP9|A8MXP9_HUMAN,tr|D6R991|D6R991_HUMAN,tr|A0A0R4J2E8|A0A0R4J2E8_HUMAN,tr|H0Y8T4|H0Y8T4_HUMAN,tr|D6REM6|D6REM6_HUMAN" 6 1785.9141 1.47 70201 19320 3 1785.913765 596.312 Matrin-3 OS=Homo sapiens OX=9606 GN=MATR3 PE=1 SV=2 5.32 3220.8 - 814642 - - - -0.187 - 2.879 0.522 - 203.8 1 2 0 -0.0003 17 0 0 0 1.63E+09 1.11E+09 - - - 7.0311 0.9999 221125_WJC_METTL3_EV_vs_WT_F05.19321.19321.4 2.52E-05 17/90 K.K[136.11]LDAGNQLALIEELHK[136.11].E sp|Q92616|GCN1_HUMAN 1 1807.0174 1.18 70202 19321 4 1807.018137 452.7616 eIF-2-alpha kinase activator GCN1 OS=Homo sapiens OX=9606 GN=GCN1 PE=1 SV=6 5.45 3221 - 418054 - - - 0.3813 - 2.719 0.442 - 262.6 1 2 0 0.0007 16 0 0 0 3.45E+06 2.91E+06 - - - 3.4253 1 221125_WJC_METTL3_EV_vs_WT_F05.19327.19327.3 1.65E-06 14/68 K.TVLQRPLSLIQGPPGTGK.T sp|Q92900|RENT1_HUMAN 1 1861.0785 1.12 70206 19327 3 1861.07847 621.3668 Regulator of nonsense transcripts 1 OS=Homo sapiens OX=9606 GN=UPF1 PE=1 SV=2 11 3221.8 - 537386 - - - -0.0333 - 2.609 0.536 - 166.5 1 2 0 -0.0001 18 0 0 0 6.97E+06 6.20E+06 - - - 6.9038 0.9954 221125_WJC_METTL3_EV_vs_WT_F05.19328.19328.3 0.0953 Nov-44 K.QVEDDIQQLLKK.L "sp|P35998|PRS7_HUMAN,tr|C9JX88|C9JX88_HUMAN,tr|C9JLS9|C9JLS9_HUMAN" 3 1455.7933 2.38 70207 19328 3 1455.794558 486.2717 26S proteasome regulatory subunit 7 OS=Homo sapiens OX=9606 GN=PSMC2 PE=1 SV=3 4.56 3221.9 - 371970 - - - 0.858 - 1.488 0.239 - 141.6 1 2 0 0.0012 12 0 0 0 5.34E+06 2.24E+06 - - - 2.3059 1 221125_WJC_METTL3_EV_vs_WT_F05.19330.19330.3 7.31E-07 17/68 K.TVLQR[166.11]PLSLIQGPPGTGK[136.11].T sp|Q92900|RENT1_HUMAN 1 1879.101 1.12 70209 19330 3 1879.102447 627.3743 Regulator of nonsense transcripts 1 OS=Homo sapiens OX=9606 GN=UPF1 PE=1 SV=2 11 3222.1 - 541086 - - - 0.769 - 3.032 0.472 - 291 1 2 0 0.0014 18 0 0 0 6.97E+06 6.20E+06 - - - 6.564 1 221125_WJC_METTL3_EV_vs_WT_F05.19331.19331.3 2.07E-10 20/60 K.K[136.11]LDAGNQLALIEELHK[136.11].E sp|Q92616|GCN1_HUMAN 1 1807.0174 1.15 70210 19331 3 1807.018664 603.3464 eIF-2-alpha kinase activator GCN1 OS=Homo sapiens OX=9606 GN=GCN1 PE=1 SV=6 5.45 3222.2 - 429057 - - - 0.6729 - 3.948 0.575 - 752.3 1 2 0 0.0012 16 0 0 0 6.71E+06 5.83E+06 - - - 8.4738 1 221125_WJC_METTL3_EV_vs_WT_F05.19332.19332.3 8.09E-08 Dec-88 K.LAIHNPNLPTTLPVNSQNIQPVR.Y sp|Q13887|KLF5_HUMAN 1 2535.3922 10.36 70211 19332 3 2535.392934 846.138 Krueppel-like factor 5 OS=Homo sapiens OX=9606 GN=KLF5 PE=1 SV=2 9.76 3222.3 - 380722 - - - 0.3073 - 2.825 0.513 - 76.7 1 2 0 0.0008 23 0 0 0 4.27E+06 4.13E+05 - - - 6.6955 0.9997 221125_WJC_METTL3_EV_vs_WT_F05.19334.19334.2 0.00127 30-Aug K.SPSSPQQQQQVLNILK[136.11].S sp|Q92793|CBP_HUMAN 1 1801.9778 0.85 70213 19334 2 1801.976996 901.9962 CREB-binding protein OS=Homo sapiens OX=9606 GN=CREBBP PE=1 SV=3 8.47 3222.6 - 161759 - - - -0.4251 - 1.702 0.422 - 152.9 1 2 0 -0.0008 16 0 0 0 1.27E+06 1.50E+06 - - - 3.4651 1 221125_WJC_METTL3_EV_vs_WT_F05.19338.19338.3 2.97E-07 15/72 R.EGAAHAFAQYNMDQFTPVK.L sp|P52907|CAZA1_HUMAN 1 2123.9735 3.88 70215 19338 3 2123.976872 708.9984 F-actin-capping protein subunit alpha-1 OS=Homo sapiens OX=9606 GN=CAPZA1 PE=1 SV=3 5.32 3223 - 785161 - - - 1.5994 - 2.851 0.62 - 234.6 1 2 0 0.0034 19 0 0 0 1.01E+07 2.61E+06 - - - 8.0254 1 221125_WJC_METTL3_EV_vs_WT_F05.19340.19340.3 2.22E-09 13/64 K.FVINYDYPNSSEDYIHR[166.11].L "sp|P17844|DDX5_HUMAN,tr|J3KTA4|J3KTA4_HUMAN,tr|A0A0G2JLI4|A0A0G2JLI4_HUMAN" 3 2140.973 1.78 70217 19340 3 2140.969515 714.6649 Probable ATP-dependent RNA helicase DDX5 OS=Homo sapiens OX=9606 GN=DDX5 PE=1 SV=1 4.54 3223.3 - 570399 - - - -1.6063 - 2.912 0.492 - 168.8 1 2 0 -0.0034 17 0 0 0 2.29E+07 1.29E+07 - - - 6.7246 1 221125_WJC_METTL3_EV_vs_WT_F05.19341.19341.3 9.09E-07 Dec-52 K.DHTLEDEDVIQIVK[136.11].K sp|Q9Y295|DRG1_HUMAN 1 1660.8399 0.48 70218 19341 3 1660.843511 554.6206 Developmentally-regulated GTP-binding protein 1 OS=Homo sapiens OX=9606 GN=DRG1 PE=1 SV=1 4.1 3223.4 - 504618 - - - 2.1555 - 2.721 0.519 - 236.8 1 2 0 0.0036 14 0 0 0 3.96E+06 8.25E+06 - - - 6.9855 1 221125_WJC_METTL3_EV_vs_WT_F05.19345.19345.3 4.80E-07 17/68 R.GGDK[136.11]PALDLYQLSPSEVK[136.11].Q sp|Q93100|KPBB_HUMAN 1 1932.0175 1.27 70220 19345 3 1932.013458 645.0131 Phosphorylase b kinase regulatory subunit beta OS=Homo sapiens OX=9606 GN=PHKB PE=1 SV=3 4.56 3223.9 - 650851 - - - -2.0963 - 3.081 0.532 - 255.2 1 2 0 -0.004 18 0 0 0 1.13E+07 8.85E+06 - - - 7.2722 1 221125_WJC_METTL3_EV_vs_WT_F05.19347.19347.3 3.42E-06 13/52 K.DHTLEDEDVIQIVK.K sp|Q9Y295|DRG1_HUMAN 1 1652.8257 0.5 70222 19347 3 1652.827047 551.9492 Developmentally-regulated GTP-binding protein 1 OS=Homo sapiens OX=9606 GN=DRG1 PE=1 SV=1 4.1 3224.2 - 326153 - - - 0.7962 - 2.47 0.502 - 229.4 1 2 0 0.0013 14 0 0 0 4.13E+06 8.29E+06 - - - 6.5394 0.9701 221125_WJC_METTL3_EV_vs_WT_F05.19349.19349.3 0.132 Jun-88 K.IGSNNSTTPTVPLK[136.11]PPPPLTLGK[136.11].T "sp|Q96CB8|INT12_HUMAN,tr|A0A087WXN4|A0A087WXN4_HUMAN" 2 2344.3337 1.19 70224 19349 3 2344.328585 782.4518 Integrator complex subunit 12 OS=Homo sapiens OX=9606 GN=INTS12 PE=1 SV=1 10 3224.5 - 239571 - - - -2.1806 - 1.468 0.211 - 20.1 3 2 0 -0.0051 23 0 0 0 6.99E+06 5.86E+06 - - - 1.5708 0.9999 221125_WJC_METTL3_EV_vs_WT_F05.19351.19351.3 0.00304 Dec-52 K.HEQILVLDPPTDLK.F "sp|Q9P0L0|VAPA_HUMAN,tr|J3QKM9|J3QKM9_HUMAN" 2 1616.8774 0.57 70226 19351 3 1616.879605 539.9664 Vesicle-associated membrane protein-associated protein A OS=Homo sapiens OX=9606 GN=VAPA PE=1 SV=3 4.54 3224.7 - 152151 - - - 1.3804 - 2.191 0.418 - 144.9 1 2 0 0.0022 14 0 0 0 2.09E+06 3.64E+06 - - - 5.2841 0.9981 221125_WJC_METTL3_EV_vs_WT_F05.19357.19357.3 2.61E-09 15/76 R.LHLETPQPSPQEGGSVDIWR[166.11].L sp|O14613|BORG1_HUMAN 1 2255.121 1.48 70230 19357 3 2256.130589 752.7143 Cdc42 effector protein 2 OS=Homo sapiens OX=9606 GN=CDC42EP2 PE=1 SV=1 4.65 3225.5 - 395282 - - - 447.6806 - 3.15 0.538 - 316.8 1 2 0 1.0096 20 0 0 0 9.28E+06 6.26E+06 - - - 7.0421 1 221125_WJC_METTL3_EV_vs_WT_F05.19358.19358.3 9.97E-07 13/76 K.VNNSSLIGLGYTQTLKPGIK.L sp|P21796|VDAC1_HUMAN 1 2102.1736 1.23 70231 19358 3 2102.178142 701.7318 Voltage-dependent anion-selective channel protein 1 OS=Homo sapiens OX=9606 GN=VDAC1 PE=1 SV=2 9.7 3225.6 - 327924 - - - 2.182 - 2.612 0.566 - 176.2 1 2 0 0.0046 20 0 0 0 1.26E+07 1.02E+07 - - - 7.1783 0.9998 221125_WJC_METTL3_EV_vs_WT_F05.19359.19359.3 1.14E-06 14/104 K.GDTPASATAGDTLSVPAPAVQPEESLK.T "tr|A0A087WYS0|A0A087WYS0_HUMAN,tr|C9J406|C9J406_HUMAN,tr|H7C463|H7C463_HUMAN" 3 2608.2868 1.63 70232 19359 3 2608.296742 870.4362 MICOS complex subunit MIC60 OS=Homo sapiens OX=9606 GN=IMMT PE=1 SV=1 3.92 3225.8 - 293769 - - - 3.8094 - 2.164 0.549 - 130 1 2 0 0.0099 27 0 0 0 4.46E+06 2.74E+06 - - - 6.434 0.8755 221125_WJC_METTL3_EV_vs_WT_F05.19361.19361.3 0.0216 13/52 L.SVTLEDLYNGATR[166.11]K[136.11].L sp|P31689|DNJA1_HUMAN 1 1583.8274 0.33 70234 19361 3 1583.833804 528.9497 DnaJ homolog subfamily A member 1 OS=Homo sapiens OX=9606 GN=DNAJA1 PE=1 SV=2 5.79 3226.1 - 263167 - - - 4.0396 - 2.527 0.335 - 156.4 1 1 0 0.0064 14 0 0 0 9.04E+05 2.72E+06 - - - 4.7368 1 221125_WJC_METTL3_EV_vs_WT_F05.19367.19367.3 2.85E-08 15/68 R.GGDKPALDLYQLSPSEVK.Q sp|Q93100|KPBB_HUMAN 1 1915.9891 1.31 70238 19367 3 1915.988078 639.6703 Phosphorylase b kinase regulatory subunit beta OS=Homo sapiens OX=9606 GN=PHKB PE=1 SV=3 4.56 3226.8 - 961819 - - - -0.5376 - 2.796 0.504 - 188.8 1 2 0 -0.001 18 0 0 0 1.16E+07 8.80E+06 - - - 6.7191 1 221125_WJC_METTL3_EV_vs_WT_F05.19370.19370.3 3.23E-05 Dec-56 R.DLK[136.11]PENIVLQDVGGK[136.11].L sp|O15111|IKKA_HUMAN 1 1639.9116 0.52 70241 19370 3 1639.911684 547.6445 Inhibitor of nuclear factor kappa-B kinase subunit alpha OS=Homo sapiens OX=9606 GN=CHUK PE=1 SV=2 4.56 3227.1 - 195749 - - - 0.0598 - 2.108 0.496 - 194.7 1 2 0 0.0001 15 0 0 0 1.42E+06 2.74E+06 - - - 6.0158 0.9999 221125_WJC_METTL3_EV_vs_WT_F05.19372.19372.3 5.13E-10 Oct-68 K.MDANSATSEEMNEIIHAR[166.11].F sp|Q9UBD5|ORC3_HUMAN 1 2027.8916 0.65 70243 19372 3 2027.88359 676.9711 Origin recognition complex subunit 3 OS=Homo sapiens OX=9606 GN=ORC3 PE=1 SV=1 4.4 3227.4 - 160158 - - - -3.9544 - 2.423 0.683 - 128 1 2 0 -0.008 18 0 0 0 1.01E+06 1.57E+06 - - - 8.3563 0.9788 221125_WJC_METTL3_EV_vs_WT_F05.19379.19379.3 3.83E-05 19/76 M.RILSAENIPNLPPGGGLAGK.R "sp|O75688|PPM1B_HUMAN,tr|B8ZZF0|B8ZZF0_HUMAN,tr|A0A3B3IS24|A0A3B3IS24_HUMAN,tr|C9JIR6|C9JIR6_HUMAN" 4 1973.1058 6.07 70248 19379 3 1973.114924 658.7092 Protein phosphatase 1B OS=Homo sapiens OX=9606 GN=PPM1B PE=1 SV=1 8.75 3228.2 - 450063 - - - 4.6191 - 3.187 0.54 - 354 1 1 0 0.0091 20 0 0 0 1.13E+07 1.86E+06 - - - 7.3699 0.9999 221125_WJC_METTL3_EV_vs_WT_F05.19380.19380.3 4.41E-05 Nov-44 K.KSDSNPLTEILK.C sp|Q96I25|SPF45_HUMAN 1 1343.7296 1.27 70249 19380 3 1343.729239 448.9172 Splicing factor 45 OS=Homo sapiens OX=9606 GN=RBM17 PE=1 SV=1 6.07 3228.3 - 346423 - - - -0.3029 - 2.154 0.441 - 242.8 1 2 0 -0.0004 12 0 0 0 9.47E+06 7.48E+06 - - - 5.5835 1 221125_WJC_METTL3_EV_vs_WT_F05.19382.19382.3 1.29E-09 Dec-64 R.GSSC[160.03]FEC[160.03]THYQSFLEYR[166.11].E "sp|P21964|COMT_HUMAN,tr|A0A7I2V370|A0A7I2V370_HUMAN" 2 2179.8967 1.19 70251 19382 3 2179.895297 727.6395 Catechol O-methyltransferase OS=Homo sapiens OX=9606 GN=COMT PE=1 SV=2 5.4 3228.6 - 273813 - - - -0.6413 - 3.149 0.698 - 237.1 1 2 0 -0.0014 17 0 0 0 4.46E+06 3.75E+06 - - - 9.2195 1 221125_WJC_METTL3_EV_vs_WT_F05.19386.19386.3 1.26E-06 15/64 K.FVINYDYPNSSEDYIHR.L "sp|P17844|DDX5_HUMAN,tr|J3KTA4|J3KTA4_HUMAN,tr|A0A0G2JLI4|A0A0G2JLI4_HUMAN" 3 2130.9647 1.89 70253 19386 3 2130.965547 711.3288 Probable ATP-dependent RNA helicase DDX5 OS=Homo sapiens OX=9606 GN=DDX5 PE=1 SV=1 4.54 3229.1 - 1.15E+06 - - - 0.405 - 2.903 0.531 - 254.4 1 2 0 0.0009 17 0 0 0 2.44E+07 1.29E+07 - - - 7.1523 1 221125_WJC_METTL3_EV_vs_WT_F05.19387.19387.3 1.13E-06 20/76 K.VNNSSLIGLGYTQTLK[136.11]PGIK[136.11].L sp|P21796|VDAC1_HUMAN 1 2118.202 1.27 70254 19387 3 2118.201755 707.0746 Voltage-dependent anion-selective channel protein 1 OS=Homo sapiens OX=9606 GN=VDAC1 PE=1 SV=2 9.7 3229.3 - 826530 - - - -0.0944 - 3.282 0.538 - 409 1 2 0 -0.0002 20 0 0 0 1.26E+07 9.88E+06 - - - 7.4213 0.8508 221125_WJC_METTL3_EV_vs_WT_F05.19388.19388.3 1.39 Oct-68 K.VWQLGSSSPNFTLEGHEK.G "sp|P35606|COPB2_HUMAN,tr|H0Y938|H0Y938_HUMAN,tr|A0A7I2V3G0|A0A7I2V3G0_HUMAN,tr|A0A7I2V258|A0A7I2V258_HUMAN,tr|H0YAC7|H0YAC7_HUMAN,tr|A0A7I2YQF9|A0A7I2YQF9_HUMAN" 6 2014.9749 1.89 70255 19388 3 2014.980282 672.6656 Coatomer subunit beta' OS=Homo sapiens OX=9606 GN=COPB2 PE=1 SV=2 5.4 3229.4 - 913937 - - - 2.6933 - 1.752 0.079 - 45.8 1 2 0 0.0054 18 0 0 0 5.49E+07 2.91E+07 - - - 0.8156 1 221125_WJC_METTL3_EV_vs_WT_F05.19389.19389.3 5.21E-07 18/72 K.K[136.11]VQGGALEDSQLVAGVAFK[136.11].K sp|Q99832|TCPH_HUMAN 1 1932.0651 0.07 70256 19389 3 1932.064672 645.029 T-complex protein 1 subunit eta OS=Homo sapiens OX=9606 GN=CCT7 PE=1 SV=2 6.07 3229.5 - 758110 - - - -0.2355 - 3.495 0.586 - 408.4 1 2 0 -0.0005 19 0 0 0 9.05E+05 1.23E+07 - - - 8.1475 1 221125_WJC_METTL3_EV_vs_WT_F05.19390.19390.3 1.52E-08 17/88 K.ASK[136.11]PLPPAPAPDEYLVSPITGEK[136.11].L "sp|Q15459|SF3A1_HUMAN,tr|H7C1L2|H7C1L2_HUMAN" 2 2392.2861 1.27 70257 19390 3 2392.286483 798.436 Splicing factor 3A subunit 1 OS=Homo sapiens OX=9606 GN=SF3A1 PE=1 SV=1 4.68 3229.6 - 597918 - - - 0.1693 - 3.224 0.677 - 235.9 1 2 0 0.0004 23 0 0 0 5.71E+07 4.51E+07 - - - 8.834 0.9998 221125_WJC_METTL3_EV_vs_WT_F05.19392.19392.3 4.09E-05 Dec-64 R.SKGFGFVC[160.03]FSSPEEATK.A "sp|Q13310|PABP4_HUMAN,sp|Q9H361|PABP3_HUMAN,sp|Q4VXU2|PAP1L_HUMAN,sp|P11940|PABP1_HUMAN,tr|A0A7I2V5W9|A0A7I2V5W9_HUMAN,tr|H0YEU6|H0YEU6_HUMAN,tr|A0A7I2YQE4|A0A7I2YQE4_HUMAN,tr|A0A7I2V649|A0A7I2V649_HUMAN,tr|B1ANR0|B1ANR0_HUMAN,tr|A0A6Q8JFT6|A0A6Q8JFT6_HUMAN,tr|A0A7I2V4L7|A0A7I2V4L7_HUMAN,tr|H0YB86|H0YB86_HUMAN,tr|H0YAR2|H0YAR2_HUMAN,tr|E7ERJ7|E7ERJ7_HUMAN,tr|A0A7I2V598|A0A7I2V598_HUMAN,tr|A0A7I2YQ88|A0A7I2YQ88_HUMAN,tr|A0A7I2V4V6|A0A7I2V4V6_HUMAN,tr|H0Y5F5|H0Y5F5_HUMAN,tr|A0A6I8PS38|A0A6I8PS38_HUMAN,tr|A0A6I8PLA1|A0A6I8PLA1_HUMAN,tr|A0A087WTT1|A0A087WTT1_HUMAN,tr|A0A7I2YQ90|A0A7I2YQ90_HUMAN,tr|A0A7I2V4N4|A0A7I2V4N4_HUMAN,tr|E7EQV3|E7EQV3_HUMAN" 24 1876.8665 1.11 70259 19392 3 1876.869393 626.6295 Polyadenylate-binding protein 4 OS=Homo sapiens OX=9606 GN=PABPC4 PE=1 SV=1 5.86 3229.9 - 372039 - - - 1.5148 - 2.858 0.473 - 199.2 1 2 1 0.0028 17 0 0 0 1.70E+07 1.54E+07 - - - 6.4656 0.9999 221125_WJC_METTL3_EV_vs_WT_F05.19393.19393.3 5.18E-06 14/52 K.NVALLSQLYHSPAR.R sp|Q15717|ELAV1_HUMAN 1 1567.8471 1.6 70260 19393 3 1567.851602 523.623 ELAV-like protein 1 OS=Homo sapiens OX=9606 GN=ELAVL1 PE=1 SV=2 8.75 3230 - 339864 - - - 2.8868 - 2.794 0.485 - 237.7 1 2 0 0.0045 14 0 0 0 2.96E+06 1.85E+06 - - - 6.6766 0.9996 221125_WJC_METTL3_EV_vs_WT_F05.19394.19394.3 0.000355 Dec-64 R.SK[136.11]GFGFVC[160.03]FSSPEEATK[136.11].A "sp|Q13310|PABP4_HUMAN,sp|Q9H361|PABP3_HUMAN,sp|Q4VXU2|PAP1L_HUMAN,sp|P11940|PABP1_HUMAN,tr|A0A7I2V5W9|A0A7I2V5W9_HUMAN,tr|H0YEU6|H0YEU6_HUMAN,tr|A0A7I2YQE4|A0A7I2YQE4_HUMAN,tr|A0A7I2V649|A0A7I2V649_HUMAN,tr|B1ANR0|B1ANR0_HUMAN,tr|A0A6Q8JFT6|A0A6Q8JFT6_HUMAN,tr|A0A7I2V4L7|A0A7I2V4L7_HUMAN,tr|H0YB86|H0YB86_HUMAN,tr|H0YAR2|H0YAR2_HUMAN,tr|E7ERJ7|E7ERJ7_HUMAN,tr|A0A7I2V598|A0A7I2V598_HUMAN,tr|A0A7I2YQ88|A0A7I2YQ88_HUMAN,tr|A0A7I2V4V6|A0A7I2V4V6_HUMAN,tr|H0Y5F5|H0Y5F5_HUMAN,tr|A0A6I8PS38|A0A6I8PS38_HUMAN,tr|A0A6I8PLA1|A0A6I8PLA1_HUMAN,tr|A0A087WTT1|A0A087WTT1_HUMAN,tr|A0A7I2YQ90|A0A7I2YQ90_HUMAN,tr|A0A7I2V4N4|A0A7I2V4N4_HUMAN,tr|E7EQV3|E7EQV3_HUMAN" 24 1892.895 1.11 70261 19394 3 1892.894331 631.9723 Polyadenylate-binding protein 4 OS=Homo sapiens OX=9606 GN=PABPC4 PE=1 SV=1 5.86 3230.1 - 280985 - - - -0.327 - 2.328 0.429 - 220.7 1 2 1 -0.0006 17 0 0 0 1.70E+07 1.54E+07 - - - 5.4575 0.9987 221125_WJC_METTL3_EV_vs_WT_F05.19396.19396.2 5.13E-05 28-Sep K.AQELIQATNQILSHR.K sp|Q9H7N4|SFR19_HUMAN 1 1720.922 -1 70263 19396 2 1720.926619 861.4683 "Splicing factor, arginine\serine-rich 19 OS=Homo sapiens OX=9606 GN=SCAF1 PE=1 SV=3" 6.79 3230.4 - 147698 - - - 2.666 - 1.878 0.381 - 255 1 2 0 0.0046 15 0 0 0 0.00E+00 0.00E+00 - - - 3.403 0.9999 221125_WJC_METTL3_EV_vs_WT_F05.19398.19398.3 1.08E-08 20/60 K.DDGK[136.11]LDLSVVENGGLK[136.11].A "sp|Q99986|VRK1_HUMAN,tr|A0A7P0T838|A0A7P0T838_HUMAN,tr|H0YJJ9|H0YJJ9_HUMAN,tr|A0A7P0TA16|A0A7P0TA16_HUMAN,tr|A0A7P0T8N0|A0A7P0T8N0_HUMAN,tr|H0YJF7|H0YJF7_HUMAN,tr|A0A7P0T9T1|A0A7P0T9T1_HUMAN,tr|A0A7P0Z4A4|A0A7P0Z4A4_HUMAN,tr|A0A7P0Z445|A0A7P0Z445_HUMAN,tr|A0A7P0TAA6|A0A7P0TAA6_HUMAN,tr|A0A7P0T9E5|A0A7P0T9E5_HUMAN,tr|A0A7P0TBB8|A0A7P0TBB8_HUMAN,tr|A0A7P0Z462|A0A7P0Z462_HUMAN,tr|A0A7P0TBE4|A0A7P0TBE4_HUMAN,tr|A0A7P0T925|A0A7P0T925_HUMAN,tr|H0YJ50|H0YJ50_HUMAN,tr|A0A7P0TA65|A0A7P0TA65_HUMAN,tr|A0A7P0T824|A0A7P0T824_HUMAN,tr|A0A7P0T9I1|A0A7P0T9I1_HUMAN,tr|A0A7P0T977|A0A7P0T977_HUMAN,tr|A0A7P0Z3Z7|A0A7P0Z3Z7_HUMAN,tr|A0A7P0TAS8|A0A7P0TAS8_HUMAN,tr|A0A7P0TB15|A0A7P0TB15_HUMAN,tr|A0A7P0T952|A0A7P0T952_HUMAN" 24 1673.8807 2.59 70264 19398 3 1673.881864 558.9675 Serine\threonine-protein kinase VRK1 OS=Homo sapiens OX=9606 GN=VRK1 PE=1 SV=1 4.23 3230.6 - 910813 - - - 0.7073 - 3.1 0.574 - 593.6 1 2 1 0.0012 16 0 0 0 3.20E+07 1.24E+07 - - - 7.8422 1 221125_WJC_METTL3_EV_vs_WT_F05.19403.19403.3 3.41E-13 24/92 K.ISTEVGITNVDLSTVDKDQSIAPK.T sp|P04844|RPN2_HUMAN 1 2529.3174 1.09 70268 19403 3 2529.316989 844.1131 Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit 2 OS=Homo sapiens OX=9606 GN=RPN2 PE=1 SV=3 4.23 3231.3 - 983117 - - - -0.1538 - 4.797 0.667 - 659.3 1 2 1 -0.0004 24 0 0 0 3.97E+07 3.63E+07 - - - 9.6181 1 221125_WJC_METTL3_EV_vs_WT_F05.19404.19404.3 0.000202 24/88 K.ASKPLPPAPAPDEYLVSPITGEK.L "sp|Q15459|SF3A1_HUMAN,tr|H7C1L2|H7C1L2_HUMAN" 2 2376.2577 1.25 70269 19404 3 2376.258491 793.0932 Splicing factor 3A subunit 1 OS=Homo sapiens OX=9606 GN=SF3A1 PE=1 SV=1 4.68 3231.4 - 910197 - - - 0.3421 - 3.746 0.585 - 567.6 1 2 0 0.0008 23 0 0 0 5.58E+07 4.45E+07 - - - 8.1602 1 221125_WJC_METTL3_EV_vs_WT_F05.19405.19405.3 2.00E-11 27/56 A.PPSSNIEDFHGLLPK[136.11].G "sp|P43243|MATR3_HUMAN,tr|A8MXP9|A8MXP9_HUMAN,tr|D6R991|D6R991_HUMAN,tr|A0A0R4J2E8|A0A0R4J2E8_HUMAN,tr|H0Y8T4|H0Y8T4_HUMAN,tr|D6REM6|D6REM6_HUMAN" 6 1657.8555 0.78 70270 19405 3 1657.856883 553.6258 Matrin-3 OS=Homo sapiens OX=9606 GN=MATR3 PE=1 SV=2 5.33 3231.5 - 766285 - - - 0.8209 - 4.076 0.605 - 1075.2 1 1 0 0.0014 15 0 0 0 9.23E+06 1.18E+07 - - - 8.9512 0.9999 221125_WJC_METTL3_EV_vs_WT_F05.19407.19407.3 6.03E-09 16/44 R.NMQDLVEDFKNK.Y "sp|P13647|K2C5_HUMAN,tr|F8W0C6|F8W0C6_HUMAN" 2 1479.7028 999 70272 19407 3 1479.701446 494.2415 "Keratin, type II cytoskeletal 5 OS=Homo sapiens OX=9606 GN=KRT5 PE=1 SV=3" 4.56 3231.8 - 522700 - - - -0.9009 - 3.041 0.576 - 426.1 1 2 1 -0.0013 12 0 0 0 6.43E+07 0.00E+00 - - - 8.0443 1 221125_WJC_METTL3_EV_vs_WT_F05.19410.19410.3 2.18E-12 32/56 A.PPSSNIEDFHGLLPK.G "sp|P43243|MATR3_HUMAN,tr|A8MXP9|A8MXP9_HUMAN,tr|D6R991|D6R991_HUMAN,tr|A0A0R4J2E8|A0A0R4J2E8_HUMAN,tr|H0Y8T4|H0Y8T4_HUMAN,tr|D6REM6|D6REM6_HUMAN" 6 1649.8413 1.03 70275 19410 3 1649.847762 550.9544 Matrin-3 OS=Homo sapiens OX=9606 GN=MATR3 PE=1 SV=2 5.33 3232.2 - 398119 - - - 3.9034 - 4.578 0.714 - 1503 1 1 0 0.0064 15 0 0 0 5.44E+07 5.29E+07 - - - 10.4681 0.9999 221125_WJC_METTL3_EV_vs_WT_F05.19411.19411.3 0.000153 Nov-44 K.NVNVQNFHISWK[136.11].D "sp|O43707|ACTN4_HUMAN,tr|F5GXS2|F5GXS2_HUMAN,tr|H7C144|H7C144_HUMAN" 3 1492.7666 4.33 70276 19411 3 1492.76521 498.5962 Alpha-actinin-4 OS=Homo sapiens OX=9606 GN=ACTN4 PE=1 SV=2 8.76 3232.3 - 378158 - - - -0.9626 - 1.878 0.432 - 115.5 1 2 0 -0.0014 12 0 0 0 1.80E+07 4.15E+06 - - - 5.1028 0.9999 221125_WJC_METTL3_EV_vs_WT_F05.19412.19412.3 4.03E-08 18/52 K.NKLNDLEDALQQAK.E sp|P04264|K2C1_HUMAN 1 1598.8264 2467.49 70277 19412 3 1598.829209 533.9494 "Keratin, type II cytoskeletal 1 OS=Homo sapiens OX=9606 GN=KRT1 PE=1 SV=6" 4.56 3232.4 - 341363 - - - 1.7569 - 3.511 0.543 - 566 1 2 1 0.0028 14 0 0 0 2.48E+08 1.01E+05 - - - 7.9307 0.9998 221125_WJC_METTL3_EV_vs_WT_F05.19414.19414.3 1.72E-06 13/52 K.NVALLSQLYHSPAR[166.11].R sp|Q15717|ELAV1_HUMAN 1 1577.8553 1.57 70279 19414 3 1577.860874 526.9591 ELAV-like protein 1 OS=Homo sapiens OX=9606 GN=ELAVL1 PE=1 SV=2 8.75 3232.7 - 221207 - - - 3.5035 - 2.621 0.446 - 239.5 1 2 0 0.0055 14 0 0 0 2.91E+06 1.85E+06 - - - 6.0716 1 221125_WJC_METTL3_EV_vs_WT_F05.19420.19420.3 8.15E-11 29/92 K.ISTEVGITNVDLSTVDK[136.11]DQSIAPK[136.11].T sp|P04844|RPN2_HUMAN 1 2545.3458 1.09 70283 19420 3 2545.342582 849.4559 Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit 2 OS=Homo sapiens OX=9606 GN=RPN2 PE=1 SV=3 4.23 3233.4 - 2.76E+06 - - - -1.2556 - 5.15 0.592 - 766.9 1 2 1 -0.0032 24 0 0 0 3.97E+07 3.63E+07 - - - 8.9461 0.9999 221125_WJC_METTL3_EV_vs_WT_F05.19423.19423.3 0.0009 15/88 R.TVATPLNQVANPNSAIFGGARPR.E "sp|Q15056|IF4H_HUMAN,tr|A0A7I2V3D5|A0A7I2V3D5_HUMAN,tr|A0A7I2V3E4|A0A7I2V3E4_HUMAN,tr|A0A7I2V4E4|A0A7I2V4E4_HUMAN" 4 2350.2506 0.84 70286 19423 3 2350.248232 784.4241 Eukaryotic translation initiation factor 4H OS=Homo sapiens OX=9606 GN=EIF4H PE=1 SV=5 12 3233.7 - 550466 - - - -0.9973 - 2.568 0.366 - 167.9 1 2 0 -0.0023 23 0 0 0 2.69E+07 3.19E+07 - - - 4.8324 0.9998 221125_WJC_METTL3_EV_vs_WT_F05.19425.19425.2 6.36E-05 30-Oct R.C[160.03]IPALDSLTPANEDQK[136.11].L "sp|P10809|CH60_HUMAN,tr|A0A7I2V2X6|A0A7I2V2X6_HUMAN,tr|A0A7I2YQK6|A0A7I2YQK6_HUMAN,tr|A0A7I2V599|A0A7I2V599_HUMAN" 4 1778.86 2.73 70288 19425 2 1778.861578 890.4373 "60 kDa heat shock protein, mitochondrial OS=Homo sapiens OX=9606 GN=HSPD1 PE=1 SV=2" 4.03 3234 - 269582 - - - 0.8787 - 1.889 0.492 - 168.4 1 2 0 0.0016 16 0 0 0 8.06E+06 2.95E+06 - - - 4.2382 1 221125_WJC_METTL3_EV_vs_WT_F05.19429.19429.3 1.76E-07 15/64 R.GAPPSSNIEDFHGLLPK.G "sp|P43243|MATR3_HUMAN,tr|A8MXP9|A8MXP9_HUMAN,tr|D6R991|D6R991_HUMAN,tr|A0A0R4J2E8|A0A0R4J2E8_HUMAN,tr|H0Y8T4|H0Y8T4_HUMAN,tr|D6REM6|D6REM6_HUMAN" 6 1777.8999 1.43 70290 19429 3 1777.899418 593.6406 Matrin-3 OS=Homo sapiens OX=9606 GN=MATR3 PE=1 SV=2 5.32 3234.5 - 1.71E+07 - - - -0.2705 - 2.751 0.598 - 236.1 1 2 0 -0.0005 17 0 0 0 1.64E+09 1.15E+09 - - - 7.7635 1 221125_WJC_METTL3_EV_vs_WT_F05.19433.19433.3 3.21E-09 14/80 K.VKTEPTEDSGISLEMAAVTVK.E "sp|P78347|GTF2I_HUMAN,tr|A0A494C1K3|A0A494C1K3_HUMAN" 2 2204.1246 1.83 70294 19433 3 2204.125095 735.7155 General transcription factor II-I OS=Homo sapiens OX=9606 GN=GTF2I PE=1 SV=2 4.41 3234.9 - 754484 - - - 0.2178 - 3.035 0.633 - 248.4 1 2 1 0.0005 21 0 0 0 2.19E+07 1.20E+07 - - - 8.2589 1 221125_WJC_METTL3_EV_vs_WT_F05.19437.19437.3 3.05E-08 Dec-48 K.VHLVGIDIFTGK[136.11]K[136.11].Y "sp|P63241|IF5A1_HUMAN,sp|Q9GZV4|IF5A2_HUMAN,sp|Q6IS14|IF5AL_HUMAN,tr|C9J4W5|C9J4W5_HUMAN,tr|I3L397|I3L397_HUMAN,tr|I3L504|I3L504_HUMAN,tr|C9J7B5|C9J7B5_HUMAN,tr|F8WCJ1|F8WCJ1_HUMAN" 8 1441.8628 0.85 70298 19437 3 1441.860578 481.6282 Eukaryotic translation initiation factor 5A-1 OS=Homo sapiens OX=9606 GN=EIF5A PE=1 SV=2 8.57 3235.5 - 181700 - - - -1.5314 - 2.634 0.539 - 216.7 1 2 0 -0.0022 13 0 0 0 2.78E+06 3.26E+06 - - - 7.1746 0.775 221125_WJC_METTL3_EV_vs_WT_F05.19441.19441.3 4.19 Jul-48 K.LLATEQEDAAVAK.S "sp|Q9P2E9|RRBP1_HUMAN,tr|A0A087WVV2|A0A087WVV2_HUMAN,tr|F8W7S5|F8W7S5_HUMAN" 3 1357.7089 14.45 70300 19441 3 1357.707518 453.5769 Ribosome-binding protein 1 OS=Homo sapiens OX=9606 GN=RRBP1 PE=1 SV=5 4.14 3236 - 553894 - - - -1.0253 - 1.436 0.085 - 64 14 2 0 -0.0014 13 0 0 0 5.55E+06 3.84E+05 - - - -0.0621 0.9999 221125_WJC_METTL3_EV_vs_WT_F05.19442.19442.3 1.90E-05 15/64 K.K[136.11]QGGLGPMNIPLVSDPK[136.11].R "sp|Q06830|PRDX1_HUMAN,tr|A0A0A0MSI0|A0A0A0MSI0_HUMAN" 2 1765.9731 0.65 70301 19442 3 1765.971922 589.665 Peroxiredoxin-1 OS=Homo sapiens OX=9606 GN=PRDX1 PE=1 SV=1 8.59 3236.1 - 1.85E+06 - - - -0.6903 - 2.29 0.463 - 238 1 2 0 -0.0012 17 0 0 0 8.66E+07 1.33E+08 - - - 5.7948 0.9998 221125_WJC_METTL3_EV_vs_WT_F05.19443.19443.3 1.11E-05 Dec-48 K.SQQERDWVLNEFK.H "sp|P17844|DDX5_HUMAN,tr|A0A7I2V5F5|A0A7I2V5F5_HUMAN,tr|A0A7I2V507|A0A7I2V507_HUMAN,tr|J3KTA4|J3KTA4_HUMAN,tr|A0A0G2JLI4|A0A0G2JLI4_HUMAN,tr|A0A7I2V2S0|A0A7I2V2S0_HUMAN" 6 1677.8111 1.11 70302 19443 3 1677.809767 560.2776 Probable ATP-dependent RNA helicase DDX5 OS=Homo sapiens OX=9606 GN=DDX5 PE=1 SV=1 4.68 3236.2 - 478095 - - - -0.785 - 2.203 0.461 - 228.6 1 2 1 -0.0013 13 0 0 0 5.62E+06 5.05E+06 - - - 5.8208 0.992 221125_WJC_METTL3_EV_vs_WT_F05.19444.19444.3 9.19E-05 Dec-68 R.AQAEAQQPTFDALRDELR.G "sp|Q15149|PLEC_HUMAN,tr|H0YDN1|H0YDN1_HUMAN" 2 2058.013 2.4 70303 19444 3 2058.022625 687.0116 Plectin OS=Homo sapiens OX=9606 GN=PLEC PE=1 SV=3 4.32 3236.3 - 263466 - - - 4.6618 - 2.183 0.397 - 208.8 1 2 1 0.0096 18 0 0 0 3.09E+06 1.29E+06 - - - 4.9075 0.9931 221125_WJC_METTL3_EV_vs_WT_F05.19446.19446.2 0.326 12-May K.ALWFQGR.C "sp|P43243|MATR3_HUMAN,tr|B3KM87|B3KM87_HUMAN,tr|A8MXP9|A8MXP9_HUMAN,tr|A0A0R4J2E8|A0A0R4J2E8_HUMAN,tr|H0Y8T4|H0Y8T4_HUMAN,tr|D6REM6|D6REM6_HUMAN" 6 876.4606 0.95 70305 19446 2 876.459981 439.2376 Matrin-3 OS=Homo sapiens OX=9606 GN=MATR3 PE=1 SV=2 9.79 3236.6 - 177190 - - - -0.7314 - 1.025 0.263 - 71.8 2 2 0 -0.0006 7 0 0 0 2.28E+06 2.39E+06 - - - 0.9271 0.996 221125_WJC_METTL3_EV_vs_WT_F05.19447.19447.3 0.631 Jul-36 K.DRPFFPGLVK.Y "sp|O60361|NDK8_HUMAN,sp|P22392|NDKB_HUMAN,tr|Q32Q12|Q32Q12_HUMAN,tr|J3KPD9|J3KPD9_HUMAN,tr|F6XY72|F6XY72_HUMAN" 5 1174.6499 1.24 70306 19447 3 1174.64744 392.5572 Putative nucleoside diphosphate kinase OS=Homo sapiens OX=9606 GN=NME2P1 PE=5 SV=1 8.75 3236.7 - 160884 - - - -2.0764 - 1.439 0.286 - 54.8 1 2 0 -0.0024 10 0 0 0 2.63E+06 2.12E+06 - - - 2.7908 0.9998 221125_WJC_METTL3_EV_vs_WT_F05.19451.19451.3 0.000132 Nov-68 R.KSTGFETLVVTSEDGITK.L "sp|O75521|ECI2_HUMAN,tr|F1LLU7|F1LLU7_HUMAN,tr|C9JB63|C9JB63_HUMAN,tr|F8WAW4|F8WAW4_HUMAN,tr|A0A0C4DGA2|A0A0C4DGA2_HUMAN" 5 1910.9837 1.61 70308 19451 3 1910.979001 638.0018 Enoyl-CoA delta isomerase 2 OS=Homo sapiens OX=9606 GN=ECI2 PE=1 SV=4 4.68 3237.1 - 496622 - - - -2.4527 - 2.545 0.423 - 189.8 1 2 0 -0.0047 18 0 0 0 5.98E+06 3.72E+06 - - - 5.5808 0.9999 221125_WJC_METTL3_EV_vs_WT_F05.19452.19452.3 7.58E-06 15/60 R.YEEALSQLEESVK[136.11]EER[166.11].K sp|Q8N8A6|DDX51_HUMAN 1 1955.9443 0.89 70309 19452 3 1955.942583 652.9887 ATP-dependent RNA helicase DDX51 OS=Homo sapiens OX=9606 GN=DDX51 PE=1 SV=3 4.21 3237.3 - 373406 - - - -0.8707 - 2.313 0.545 - 135.6 1 2 1 -0.0017 16 0 0 0 6.38E+06 7.18E+06 - - - 6.7673 1 221125_WJC_METTL3_EV_vs_WT_F05.19453.19453.2 7.82E-05 18/26 K.NKLNDLEDALQQAK.E sp|P04264|K2C1_HUMAN 1 1598.8264 660.51 70310 19453 2 1598.821924 800.4205 "Keratin, type II cytoskeletal 1 OS=Homo sapiens OX=9606 GN=KRT1 PE=1 SV=6" 4.56 3237.3 - 2.88E+06 - - - -2.7996 - 3.657 0.64 - 1162.8 1 2 1 -0.0045 14 0 0 0 6.48E+07 9.82E+04 - - - 7.0205 0.9992 221125_WJC_METTL3_EV_vs_WT_F05.19455.19455.4 0.000455 13/96 K.FMQASEDLLKEHYVDLK.D "sp|P15531|NDKA_HUMAN,tr|Q32Q12|Q32Q12_HUMAN,tr|J3KPD9|J3KPD9_HUMAN,tr|E5RHP0|E5RHP0_HUMAN,tr|E7ERL0|E7ERL0_HUMAN" 5 2065.019 1.63 70312 19455 4 2065.019719 517.262 Nucleoside diphosphate kinase A OS=Homo sapiens OX=9606 GN=NME1 PE=1 SV=1 4.75 3237.6 - 301041 - - - 0.3346 - 2.234 0.379 - 99 1 2 1 0.0007 17 0 0 0 5.84E+06 3.59E+06 - - - 2.8037 0.9999 221125_WJC_METTL3_EV_vs_WT_F05.19457.19457.4 0.000161 11/102 R.LEAARPSAVLDLVHSAER.L sp|Q7Z7A3|CTU1_HUMAN 1 1933.0381 1.31 70314 19457 4 1933.038229 484.2668 Cytoplasmic tRNA 2-thiolation protein 1 OS=Homo sapiens OX=9606 GN=CTU1 PE=1 SV=1 5.45 3237.9 - 197624 - - - 0.0543 - 2.322 0.399 - 89.7 1 2 0 0.0001 18 0 0 0 4.16E+06 3.16E+06 - - - 2.9874 0.9999 221125_WJC_METTL3_EV_vs_WT_F05.19458.19458.4 0.000421 13/102 R.LEAAR[166.11]PSAVLDLVHSAER[166.11].L sp|Q7Z7A3|CTU1_HUMAN 1 1953.0547 1.31 70315 19458 4 1953.054164 489.2709 Cytoplasmic tRNA 2-thiolation protein 1 OS=Homo sapiens OX=9606 GN=CTU1 PE=1 SV=1 5.45 3238 - 170484 - - - -0.256 - 1.99 0.421 - 110.5 1 2 0 -0.0005 18 0 0 0 4.16E+06 3.16E+06 - - - 3.126 1 221125_WJC_METTL3_EV_vs_WT_F05.19461.19461.3 6.59E-08 17/88 R.TVATPLNQVANPNSAIFGGAR[166.11]PR[166.11].E "sp|Q15056|IF4H_HUMAN,tr|A0A7I2V3D5|A0A7I2V3D5_HUMAN,tr|A0A7I2V3E4|A0A7I2V3E4_HUMAN,tr|A0A7I2V4E4|A0A7I2V4E4_HUMAN" 4 2370.2671 0.84 70316 19461 3 2370.265027 791.0963 Eukaryotic translation initiation factor 4H OS=Homo sapiens OX=9606 GN=EIF4H PE=1 SV=5 12 3238.4 - 1.57E+06 - - - -0.8813 - 3.056 0.527 - 189.3 1 2 0 -0.0021 23 0 0 0 2.69E+07 3.19E+07 - - - 7.0356 1 221125_WJC_METTL3_EV_vs_WT_F05.19462.19462.3 0.000172 16/60 R.FSHQGVQLIDFSPC[160.03]ER[166.11].Y "sp|P55884|EIF3B_HUMAN,tr|C9JQN7|C9JQN7_HUMAN" 2 1928.9079 1.46 70317 19462 3 1928.907064 643.9766 Eukaryotic translation initiation factor 3 subunit B OS=Homo sapiens OX=9606 GN=EIF3B PE=1 SV=3 5.32 3238.5 - 451946 - - - -0.4085 - 3.124 0.447 - 363.5 1 2 0 -0.0008 16 0 0 0 2.21E+07 1.51E+07 - - - 6.4462 1 221125_WJC_METTL3_EV_vs_WT_F05.19463.19463.3 3.42E-05 13/52 K.KADVDAIHEYLLLK.G sp|Q9UJV9|DDX41_HUMAN 1 1626.8981 0.84 70318 19463 3 1626.899355 543.3066 Probable ATP-dependent RNA helicase DDX41 OS=Homo sapiens OX=9606 GN=DDX41 PE=1 SV=2 5.38 3238.6 - 403389 - - - 0.7665 - 2.786 0.498 - 194.1 1 2 0 0.0012 14 0 0 0 6.41E+06 7.67E+06 - - - 6.8148 1 221125_WJC_METTL3_EV_vs_WT_F05.19466.19466.4 2.38E-05 13/78 K.K[136.11]ADVDAIHEYLLLK[136.11].G sp|Q9UJV9|DDX41_HUMAN 1 1642.9265 0.76 70321 19466 4 1642.9237 411.7389 Probable ATP-dependent RNA helicase DDX41 OS=Homo sapiens OX=9606 GN=DDX41 PE=1 SV=2 5.38 3239 - 184030 - - - -1.7091 - 2.789 0.488 - 155.4 1 2 0 -0.0028 14 0 0 0 1.80E+06 2.37E+06 - - - 3.8461 1 221125_WJC_METTL3_EV_vs_WT_F05.19471.19471.3 1.20E-07 18/52 K.K[136.11]ADVDAIHEYLLLK[136.11].G sp|Q9UJV9|DDX41_HUMAN 1 1642.9265 0.89 70324 19471 3 1642.928227 548.6494 Probable ATP-dependent RNA helicase DDX41 OS=Homo sapiens OX=9606 GN=DDX41 PE=1 SV=2 5.38 3239.6 - 662384 - - - 1.0463 - 3.298 0.575 - 481.4 1 2 0 0.0017 14 0 0 0 6.90E+06 7.78E+06 - - - 8.1215 0.9898 221125_WJC_METTL3_EV_vs_WT_F05.19473.19473.4 4.71E-05 Dec-96 K.FMQASEDLLK[136.11]EHYVDLK[136.11].D "sp|P15531|NDKA_HUMAN,tr|Q32Q12|Q32Q12_HUMAN,tr|J3KPD9|J3KPD9_HUMAN,tr|E5RHP0|E5RHP0_HUMAN,tr|E7ERL0|E7ERL0_HUMAN" 5 2081.0474 1.62 70326 19473 4 2081.044452 521.2691 Nucleoside diphosphate kinase A OS=Homo sapiens OX=9606 GN=NME1 PE=1 SV=1 4.75 3239.9 - 327414 - - - -1.43 - 2.136 0.251 - 79.5 1 2 1 -0.003 17 0 0 0 5.77E+06 3.56E+06 - - - 1.6734 0.9999 221125_WJC_METTL3_EV_vs_WT_F05.19474.19474.4 1.87E-06 14/108 K.ILGSGISSSSVLHGMVFK[136.11]K[136.11].E sp|P50990|TCPQ_HUMAN 1 1962.0943 0.26 70327 19474 4 1962.090985 491.5309 T-complex protein 1 subunit theta OS=Homo sapiens OX=9606 GN=CCT8 PE=1 SV=4 10 3240 - 253628 - - - -1.6992 - 2.931 0.446 - 136.3 1 2 0 -0.0033 19 0 0 0 2.64E+06 1.03E+07 - - - 3.4708 0.9995 221125_WJC_METTL3_EV_vs_WT_F05.19475.19475.4 0.000106 Sep-84 R.GFVFITFK[136.11]EEEPVK[136.11]K[136.11].V "sp|Q99729|ROAA_HUMAN,tr|D6R9P3|D6R9P3_HUMAN,tr|D6RD18|D6RD18_HUMAN,tr|D6RBZ0|D6RBZ0_HUMAN" 4 1821.0139 1.51 70328 19475 4 1821.010292 456.2607 Heterogeneous nuclear ribonucleoprotein A\B OS=Homo sapiens OX=9606 GN=HNRNPAB PE=1 SV=2 6.23 3240.1 - 240619 - - - -1.9665 - 2.114 0.434 - 42.5 1 2 1 -0.0036 15 0 0 0 3.86E+07 2.55E+07 - - - 3.2704 1 221125_WJC_METTL3_EV_vs_WT_F05.19476.19476.4 2.28E-07 14/84 R.DHGLLIYHIPQVEPR.D sp|Q9Y676|RT18B_HUMAN 1 1785.9526 0.52 70329 19476 4 1785.95174 447.4954 "28S ribosomal protein S18b, mitochondrial OS=Homo sapiens OX=9606 GN=MRPS18B PE=1 SV=1" 5.99 3240.2 - 238847 - - - -0.4832 - 2.475 0.563 - 187.8 1 2 0 -0.0009 15 0 0 0 7.39E+06 1.41E+07 - - - 4.4504 1 221125_WJC_METTL3_EV_vs_WT_F05.19481.19481.3 4.39E-09 18/64 K.KQGGLGPMNIPLVSDPK.R "sp|Q06830|PRDX1_HUMAN,tr|A0A0A0MSI0|A0A0A0MSI0_HUMAN" 2 1749.9447 0.65 70332 19481 3 1749.944229 584.3222 Peroxiredoxin-1 OS=Homo sapiens OX=9606 GN=PRDX1 PE=1 SV=1 8.59 3240.9 - 3.49E+06 - - - -0.2926 - 3.579 0.585 - 379 1 2 0 -0.0005 17 0 0 0 8.66E+07 1.33E+08 - - - 8.2833 0.9999 221125_WJC_METTL3_EV_vs_WT_F05.19482.19482.4 3.74E-11 19/108 R.LNR[166.11]LPAAGVGDMVMATVK[136.11]K[136.11].G "sp|P62829|RL23_HUMAN,tr|J3KT29|J3KT29_HUMAN,tr|B9ZVP7|B9ZVP7_HUMAN,tr|C9JD32|C9JD32_HUMAN" 4 1996.1172 0.9 70333 19482 4 1996.114201 500.0366 60S ribosomal protein L23 OS=Homo sapiens OX=9606 GN=RPL23 PE=1 SV=1 9.99 3241 - 476162 - - - -1.4989 - 3.796 0.615 - 361.5 1 2 1 -0.003 19 0 0 0 6.43E+06 7.18E+06 - - - 5.0294 0.922 221125_WJC_METTL3_EV_vs_WT_F05.19485.19485.3 6.73E-09 17/76 R.YVELFLNSTAGASGGAYEHR[166.11].Y "sp|P31943|HNRH1_HUMAN,tr|H0YB39|H0YB39_HUMAN,tr|G8JLB6|G8JLB6_HUMAN" 3 2151.0261 0.8 70336 19485 3 2151.032184 718.016 Heterogeneous nuclear ribonucleoprotein H OS=Homo sapiens OX=9606 GN=HNRNPH1 PE=1 SV=4 5.4 3241.3 - 761111 - - - 2.8507 - 2.905 0.027 - 224.7 2 2 0 0.0061 20 0 0 0 1.28E+07 1.60E+07 - - - 1.2872 0.9264 221125_WJC_METTL3_EV_vs_WT_F05.19486.19486.4 3.27E-05 15/84 R.GFVFITFKEEEPVKK.V "sp|Q99729|ROAA_HUMAN,tr|D6R9P3|D6R9P3_HUMAN,tr|D6RD18|D6RD18_HUMAN,tr|D6RBZ0|D6RBZ0_HUMAN" 4 1796.9713 1.58 70337 19486 4 1796.965704 450.2501 Heterogeneous nuclear ribonucleoprotein A\B OS=Homo sapiens OX=9606 GN=HNRNPAB PE=1 SV=2 6.23 3241.5 - 496343 - - - -3.0991 - 2.838 0.201 - 139.8 1 2 1 -0.0056 15 0 0 0 4.05E+07 2.56E+07 - - - 1.3472 1 221125_WJC_METTL3_EV_vs_WT_F05.19487.19487.3 3.08E-06 15/68 K.VVTATLWGEDADK[136.11]FDGSR[166.11].Q "sp|P27694|RFA1_HUMAN,tr|I3L4R8|I3L4R8_HUMAN" 2 1983.9657 1.37 70338 19487 3 1983.964707 662.3292 Replication protein A 70 kDa DNA-binding subunit OS=Homo sapiens OX=9606 GN=RPA1 PE=1 SV=2 4.23 3241.6 - 372630 - - - -0.4955 - 3.217 0.608 - 207.5 1 2 1 -0.001 18 0 0 0 6.98E+06 5.09E+06 - - - 8.2279 0.998 221125_WJC_METTL3_EV_vs_WT_F05.19488.19488.2 0.00445 Oct-32 R.GAPPSSNIEDFHGLLPK[136.11].G "sp|P43243|MATR3_HUMAN,tr|A8MXP9|A8MXP9_HUMAN,tr|D6R991|D6R991_HUMAN,tr|A0A0R4J2E8|A0A0R4J2E8_HUMAN,tr|H0Y8T4|H0Y8T4_HUMAN,tr|D6REM6|D6REM6_HUMAN" 6 1785.9141 1.02 70339 19488 2 1785.91816 893.9643 Matrin-3 OS=Homo sapiens OX=9606 GN=MATR3 PE=1 SV=2 5.32 3241.7 - 314506 - - - 2.2739 - 1.593 0.335 - 181.6 1 2 0 0.0041 17 0 0 0 2.03E+07 2.00E+07 - - - 2.6588 0.9998 221125_WJC_METTL3_EV_vs_WT_F05.19491.19491.4 6.01E-08 25/120 R.SPTLYGISHDDLKGDPLLDQR.R "sp|O75643|U520_HUMAN,tr|A0A494C1A5|A0A494C1A5_HUMAN" 2 2339.1757 0.84 70340 19491 4 2339.180109 585.8012 U5 small nuclear ribonucleoprotein 200 kDa helicase OS=Homo sapiens OX=9606 GN=SNRNP200 PE=1 SV=2 4.56 3242.1 - 1.01E+06 - - - 1.8678 - 3.066 0.517 - 334.5 1 2 1 0.0044 21 0 0 0 1.82E+07 2.16E+07 - - - 4.0952 1 221125_WJC_METTL3_EV_vs_WT_F05.19494.19494.3 7.82E-12 21/68 K.VVTATLWGEDADKFDGSR.Q "sp|P27694|RFA1_HUMAN,tr|I3L4R8|I3L4R8_HUMAN" 2 1965.9432 1.36 70343 19494 3 1965.944327 656.3217 Replication protein A 70 kDa DNA-binding subunit OS=Homo sapiens OX=9606 GN=RPA1 PE=1 SV=2 4.23 3242.5 - 456483 - - - 0.5631 - 4.069 0.699 - 501.6 1 2 1 0.0011 18 0 0 0 7.05E+06 5.17E+06 - - - 9.8275 1 221125_WJC_METTL3_EV_vs_WT_F05.19496.19496.3 0.000595 18/68 R.LEIC[160.03]NLTPDTLTSDTYKK.W sp|P17655|CAN2_HUMAN 1 2111.0456 0.35 70345 19496 3 2111.045376 704.6892 Calpain-2 catalytic subunit OS=Homo sapiens OX=9606 GN=CAPN2 PE=1 SV=6 4.56 3242.8 - 413427 - - - -0.1236 - 2.925 0.504 - 358.8 1 2 0 -0.0003 18 0 0 0 1.14E+07 3.23E+07 - - - 6.8316 0.9749 221125_WJC_METTL3_EV_vs_WT_F05.19497.19497.3 0.139 Oct-44 R.NKLAELEEALQK.A "sp|P13647|K2C5_HUMAN,tr|H0YI76|H0YI76_HUMAN" 2 1384.7562 42.44 70346 19497 3 1384.756019 462.5927 "Keratin, type II cytoskeletal 5 OS=Homo sapiens OX=9606 GN=KRT5 PE=1 SV=3" 4.79 3242.9 - 276524 - - - -0.1271 - 1.766 0.184 - 132.7 1 2 1 -0.0002 12 0 0 0 6.19E+06 1.46E+05 - - - 2.1678 0.9999 221125_WJC_METTL3_EV_vs_WT_F05.19498.19498.4 4.75E-05 11/108 K.ILGSGISSSSVLHGMVFKK.E sp|P50990|TCPQ_HUMAN 1 1946.0659 0.26 70347 19498 4 1946.064989 487.5238 T-complex protein 1 subunit theta OS=Homo sapiens OX=9606 GN=CCT8 PE=1 SV=4 10 3243 - 205246 - - - -0.4779 - 2.356 0.441 - 86.4 1 2 0 -0.0009 19 0 0 0 2.67E+06 1.03E+07 - - - 3.3541 0.9986 221125_WJC_METTL3_EV_vs_WT_F05.19503.19503.3 0.0328 Jun-84 R.QWVDTDDTSSENTVVPPETYVK[136.11].V "sp|P15927|RFA2_HUMAN,tr|Q5TEJ7|Q5TEJ7_HUMAN" 2 2517.1638 1.67 70350 19503 3 2517.160336 840.0619 Replication protein A 32 kDa subunit OS=Homo sapiens OX=9606 GN=RPA2 PE=1 SV=1 3.77 3243.7 - 256926 - - - -1.3936 - 1.541 0.329 - 19.8 1 2 0 -0.0035 22 0 0 0 1.38E+07 8.27E+06 - - - 3.2323 0.9984 221125_WJC_METTL3_EV_vs_WT_F05.19507.19507.3 0.0183 Jul-40 R.GFC[160.03]FLEYEDHK.T "sp|O60506|HNRPQ_HUMAN,sp|O43390|HNRPR_HUMAN,tr|A0A7I2YQV8|A0A7I2YQV8_HUMAN,tr|B4DT28|B4DT28_HUMAN,tr|A0A7I2YQN2|A0A7I2YQN2_HUMAN,tr|A0A7I2V5Q6|A0A7I2V5Q6_HUMAN,tr|A0A7I2V4Z0|A0A7I2V4Z0_HUMAN,tr|A0A6Q8PHG0|A0A6Q8PHG0_HUMAN,tr|B7Z645|B7Z645_HUMAN,tr|A0A6Q8PH31|A0A6Q8PH31_HUMAN,tr|A0A6Q8PEX7|A0A6Q8PEX7_HUMAN,tr|A0A7I2V2F2|A0A7I2V2F2_HUMAN,tr|A0A7I2V346|A0A7I2V346_HUMAN,tr|A0A7I2V309|A0A7I2V309_HUMAN" 14 1443.6129 2.27 70354 19507 3 1443.612635 482.2116 Heterogeneous nuclear ribonucleoprotein Q OS=Homo sapiens OX=9606 GN=SYNCRIP PE=1 SV=2 4.65 3244.2 - 208249 - - - -0.185 - 1.255 0.34 - 37.9 1 2 0 -0.0003 11 0 0 0 3.02E+06 1.33E+06 - - - 2.9758 1 221125_WJC_METTL3_EV_vs_WT_F05.19508.19508.2 1.10E-07 13/34 R.LSSSQGTIETSLQDIDSR.L "sp|Q9UHD2|TBK1_HUMAN,tr|A0A7I2V646|A0A7I2V646_HUMAN,tr|A0A494C045|A0A494C045_HUMAN,tr|A0A494C1M6|A0A494C1M6_HUMAN,tr|A0A494C0A8|A0A494C0A8_HUMAN,tr|A0A7I2V4W4|A0A7I2V4W4_HUMAN,tr|A0A7I2V463|A0A7I2V463_HUMAN,tr|A0A494C148|A0A494C148_HUMAN,tr|A0A494C0X2|A0A494C0X2_HUMAN,tr|A0A7I2V387|A0A7I2V387_HUMAN,tr|A0A7I2V2N0|A0A7I2V2N0_HUMAN,tr|A0A494C167|A0A494C167_HUMAN,tr|A0A7I2V2F4|A0A7I2V2F4_HUMAN,tr|A0A494C0R4|A0A494C0R4_HUMAN" 14 1935.9385 1.72 70355 19508 2 1935.943406 968.9765 Serine\threonine-protein kinase TBK1 OS=Homo sapiens OX=9606 GN=TBK1 PE=1 SV=1 4.03 3244.3 - 192771 - - - 2.5192 - 2.845 0.671 - 487.6 1 2 0 0.0049 18 0 0 0 4.01E+06 2.33E+06 - - - 6.566 0.9996 221125_WJC_METTL3_EV_vs_WT_F05.19511.19511.3 9.75E-06 15/56 R.GFVFITFKEEEPVKK.V "sp|Q99729|ROAA_HUMAN,tr|D6R9P3|D6R9P3_HUMAN,tr|D6RD18|D6RD18_HUMAN,tr|D6RBZ0|D6RBZ0_HUMAN" 4 1796.9713 1.72 70356 19511 3 1796.969654 599.9977 Heterogeneous nuclear ribonucleoprotein A\B OS=Homo sapiens OX=9606 GN=HNRNPAB PE=1 SV=2 6.23 3244.7 - 1.58E+06 - - - -0.901 - 3.138 0.344 - 259.8 1 2 1 -0.0016 15 0 0 0 2.34E+07 1.36E+07 - - - 5.3588 0.9998 221125_WJC_METTL3_EV_vs_WT_F05.19513.19513.2 2.21E-05 13/30 R.C[160.03]IPALDSLTPANEDQK.L "sp|P10809|CH60_HUMAN,tr|A0A7I2V2X6|A0A7I2V2X6_HUMAN,tr|A0A7I2YQK6|A0A7I2YQK6_HUMAN,tr|A0A7I2V599|A0A7I2V599_HUMAN" 4 1770.8458 7.41 70358 19513 2 1770.848101 886.4302 "60 kDa heat shock protein, mitochondrial OS=Homo sapiens OX=9606 GN=HSPD1 PE=1 SV=2" 4.03 3245 - 1.11E+06 - - - 1.2909 - 2.105 0.484 - 260.6 1 2 0 0.0023 16 0 0 0 3.44E+07 4.63E+06 - - - 4.445 0.9999 221125_WJC_METTL3_EV_vs_WT_F05.19514.19514.3 1.07E-07 14/56 R.GFVFITFK[136.11]EEEPVK[136.11]K[136.11].V "sp|Q99729|ROAA_HUMAN,tr|D6R9P3|D6R9P3_HUMAN,tr|D6RD18|D6RD18_HUMAN,tr|D6RBZ0|D6RBZ0_HUMAN" 4 1821.0139 1.7 70359 19514 3 1821.014854 608.0119 Heterogeneous nuclear ribonucleoprotein A\B OS=Homo sapiens OX=9606 GN=HNRNPAB PE=1 SV=2 6.23 3245.1 - 784505 - - - 0.5387 - 3.223 0.579 - 220.9 1 2 1 0.001 15 0 0 0 2.31E+07 1.36E+07 - - - 8.0488 1 221125_WJC_METTL3_EV_vs_WT_F05.19515.19515.3 3.58E-10 26/80 R.SPTLYGISHDDLKGDPLLDQR.R "sp|O75643|U520_HUMAN,tr|A0A494C1A5|A0A494C1A5_HUMAN" 2 2339.1757 1.57 70360 19515 3 2339.178637 780.7325 U5 small nuclear ribonucleoprotein 200 kDa helicase OS=Homo sapiens OX=9606 GN=SNRNP200 PE=1 SV=2 4.56 3245.2 - 657255 - - - 1.2385 - 4.798 0.655 - 641.9 1 2 1 0.0029 21 0 0 0 4.45E+06 2.84E+06 - - - 9.6015 0.9999 221125_WJC_METTL3_EV_vs_WT_F05.19516.19516.3 1.02E-08 17/80 R.SPTLYGISHDDLK[136.11]GDPLLDQR[166.11].R "sp|O75643|U520_HUMAN,tr|A0A494C1A5|A0A494C1A5_HUMAN" 2 2357.1982 1.59 70361 19516 3 2357.201076 786.74 U5 small nuclear ribonucleoprotein 200 kDa helicase OS=Homo sapiens OX=9606 GN=SNRNP200 PE=1 SV=2 4.56 3245.4 - 536958 - - - 1.2159 - 3.19 0.629 - 265.3 1 2 1 0.0029 21 0 0 0 4.51E+06 2.84E+06 - - - 8.333 0.9999 221125_WJC_METTL3_EV_vs_WT_F05.19518.19518.4 3.72E-05 12/108 R.LNRLPAAGVGDMVMATVKK.G "sp|P62829|RL23_HUMAN,tr|J3KT29|J3KT29_HUMAN,tr|B9ZVP7|B9ZVP7_HUMAN,tr|C9JD32|C9JD32_HUMAN" 4 1970.0805 0.9 70363 19518 4 1970.082314 493.5274 60S ribosomal protein L23 OS=Homo sapiens OX=9606 GN=RPL23 PE=1 SV=1 9.99 3245.6 - 387188 - - - 0.9091 - 2.811 0.492 - 78.3 1 2 1 0.0018 19 0 0 0 6.43E+06 7.18E+06 - - - 3.8575 0.9999 221125_WJC_METTL3_EV_vs_WT_F05.19522.19522.3 0.000216 Aug-36 R.KDAEEWFFTK.T sp|P02533|K1C14_HUMAN 1 1299.6136 999 70367 19522 3 1299.614361 434.2118 "Keratin, type I cytoskeletal 14 OS=Homo sapiens OX=9606 GN=KRT14 PE=1 SV=4" 4.68 3246.1 - 140973 - - - 0.6217 - 1.565 0.505 - 111.6 1 2 0 0.0008 10 0 0 0 1.76E+06 0.00E+00 - - - 5.478 0.9999 221125_WJC_METTL3_EV_vs_WT_F05.19526.19526.3 0.000458 13/56 R.NHLLPDIVTC[160.03]VQSSR.K sp|Q9BSD7|NTPCR_HUMAN 1 1737.8832 1.18 70369 19526 3 1737.878352 580.3017 Cancer-related nucleoside-triphosphatase OS=Homo sapiens OX=9606 GN=NTPCR PE=1 SV=1 6.74 3246.6 - 2.10E+06 - - - -2.7913 - 2.55 0.493 - 191.6 1 2 0 -0.0049 15 0 0 0 4.01E+08 3.39E+08 - - - 6.4777 0.9983 221125_WJC_METTL3_EV_vs_WT_F05.19531.19531.3 0.00786 Sep-68 R.SVEEEIEQEKQATDDIIK.N sp|Q96LB3|IFT74_HUMAN 1 2103.0219 1.82 70374 19531 3 2103.019525 702.0146 Intraflagellar transport protein 74 homolog OS=Homo sapiens OX=9606 GN=IFT74 PE=1 SV=1 4 3247.3 - 263622 - - - -1.1407 - 1.832 0.366 - 45.8 1 2 1 -0.0024 18 0 0 0 3.17E+06 1.75E+06 - - - 4.1274 0.9979 221125_WJC_METTL3_EV_vs_WT_F05.19533.19533.3 0.0333 Jul-40 R.GFC[160.03]FLEYEDHK[136.11].T "sp|O60506|HNRPQ_HUMAN,sp|O43390|HNRPR_HUMAN,tr|A0A7I2YQV8|A0A7I2YQV8_HUMAN,tr|B4DT28|B4DT28_HUMAN,tr|A0A7I2YQN2|A0A7I2YQN2_HUMAN,tr|A0A7I2V5Q6|A0A7I2V5Q6_HUMAN,tr|A0A7I2V4Z0|A0A7I2V4Z0_HUMAN,tr|A0A6Q8PHG0|A0A6Q8PHG0_HUMAN,tr|B7Z645|B7Z645_HUMAN,tr|A0A6Q8PH31|A0A6Q8PH31_HUMAN,tr|A0A6Q8PEX7|A0A6Q8PEX7_HUMAN,tr|A0A7I2V2F2|A0A7I2V2F2_HUMAN,tr|A0A7I2V346|A0A7I2V346_HUMAN,tr|A0A7I2V309|A0A7I2V309_HUMAN" 14 1451.6271 2.34 70376 19533 3 1451.627866 484.883 Heterogeneous nuclear ribonucleoprotein Q OS=Homo sapiens OX=9606 GN=SYNCRIP PE=1 SV=2 4.65 3247.5 - 164708 - - - 0.5263 - 1.266 0.321 - 39.7 1 2 0 0.0008 11 0 0 0 3.12E+06 1.33E+06 - - - 2.7887 1 221125_WJC_METTL3_EV_vs_WT_F05.19537.19537.3 3.23E-10 25/72 K.NAQAIEDMVGYAQETQHEK[136.11].L "sp|Q99460|PSMD1_HUMAN,tr|A0A7I2V4X0|A0A7I2V4X0_HUMAN,tr|A0A7I2V2K8|A0A7I2V2K8_HUMAN,tr|A0A7I2YQY1|A0A7I2YQY1_HUMAN,tr|A0A7I2V523|A0A7I2V523_HUMAN,tr|A0A7I2V641|A0A7I2V641_HUMAN,tr|A0A7I2V491|A0A7I2V491_HUMAN,tr|A0A7I2YQI9|A0A7I2YQI9_HUMAN,tr|A0A7I2V262|A0A7I2V262_HUMAN,tr|A0A087WW66|A0A087WW66_HUMAN,tr|A0A7P0MW50|A0A7P0MW50_HUMAN,tr|A0A7I2V5C8|A0A7I2V5C8_HUMAN,tr|A0A7I2V479|A0A7I2V479_HUMAN" 13 2168.9888 0.49 70378 19537 3 2168.985496 724.0035 26S proteasome non-ATPase regulatory subunit 1 OS=Homo sapiens OX=9606 GN=PSMD1 PE=1 SV=2 4.4 3248 - 1.29E+06 - - - -1.5219 - 4.173 0.629 - 895.8 1 2 0 -0.0033 19 0 0 0 8.48E+06 1.74E+07 - - - 9.0617 0.9999 221125_WJC_METTL3_EV_vs_WT_F05.19538.19538.3 3.94E-06 15/56 K.YK[136.11]DNPFSLGESFGSR[166.11].W "sp|Q8N6H7|ARFG2_HUMAN,tr|E9PMU9|E9PMU9_HUMAN,tr|E9PQP3|E9PQP3_HUMAN,tr|H0YDN9|H0YDN9_HUMAN,tr|G5E9L0|G5E9L0_HUMAN,tr|A0A0D9SF70|A0A0D9SF70_HUMAN" 6 1720.8176 1.02 70379 19538 3 1720.818342 574.6131 ADP-ribosylation factor GTPase-activating protein 2 OS=Homo sapiens OX=9606 GN=ARFGAP2 PE=1 SV=1 6.07 3248.1 - 992519 - - - 0.4486 - 2.548 0.516 - 210.1 1 2 1 0.0008 15 0 0 0 2.14E+07 2.09E+07 - - - 6.7332 0.9999 221125_WJC_METTL3_EV_vs_WT_F05.19539.19539.4 2.28E-09 22/108 K.NTKEPPLSLTIHLTSPVVR.E "sp|Q12906|ILF3_HUMAN,tr|K7EQR9|K7EQR9_HUMAN,tr|K7EKY0|K7EKY0_HUMAN,tr|K7EPG3|K7EPG3_HUMAN,tr|K7EKJ9|K7EKJ9_HUMAN" 5 2101.1895 0.99 70380 19539 4 2101.190965 526.3047 Interleukin enhancer-binding factor 3 OS=Homo sapiens OX=9606 GN=ILF3 PE=1 SV=3 8.75 3248.3 - 445368 - - - 0.6787 - 3.657 0.548 - 480.6 1 2 1 0.0014 19 0 0 0 5.40E+06 5.44E+06 - - - 4.434 1 221125_WJC_METTL3_EV_vs_WT_F05.19547.19547.3 1.28E-09 17/56 R.NHLLPDIVTC[160.03]VQSSR[166.11].K sp|Q9BSD7|NTPCR_HUMAN 1 1747.8915 1.18 70386 19547 3 1747.89161 583.6378 Cancer-related nucleoside-triphosphatase OS=Homo sapiens OX=9606 GN=NTPCR PE=1 SV=1 6.74 3249.2 - 6.31E+06 - - - 0.0784 - 3.155 0.614 - 487.7 1 2 0 0.0001 15 0 0 0 3.99E+08 3.37E+08 - - - 8.3836 0.9999 221125_WJC_METTL3_EV_vs_WT_F05.19548.19548.3 0.000457 16/56 K.NGFRPLDVSLYAQQR.Y sp|Q92615|LAR4B_HUMAN 1 1762.9115 0.47 70387 19548 3 1762.91271 588.6444 La-related protein 4B OS=Homo sapiens OX=9606 GN=LARP4B PE=1 SV=3 8.75 3249.3 - 1.41E+06 - - - 0.7051 - 2.591 0.416 - 305.6 1 2 0 0.0012 15 0 0 0 1.16E+07 2.49E+07 - - - 5.6619 0.9997 221125_WJC_METTL3_EV_vs_WT_F05.19550.19550.3 0.000149 Dec-56 K.YKDNPFSLGESFGSR.W "sp|Q8N6H7|ARFG2_HUMAN,tr|E9PMU9|E9PMU9_HUMAN,tr|E9PQP3|E9PQP3_HUMAN,tr|H0YDN9|H0YDN9_HUMAN,tr|G5E9L0|G5E9L0_HUMAN,tr|A0A0D9SF70|A0A0D9SF70_HUMAN" 6 1702.7951 1.02 70389 19550 3 1702.796326 568.6056 ADP-ribosylation factor GTPase-activating protein 2 OS=Homo sapiens OX=9606 GN=ARFGAP2 PE=1 SV=1 6.07 3249.5 - 1.50E+06 - - - 0.72 - 2.475 0.423 - 187.5 1 2 1 0.0012 15 0 0 0 2.14E+07 2.09E+07 - - - 5.6204 0.9999 221125_WJC_METTL3_EV_vs_WT_F05.19554.19554.4 5.97E-07 21/108 K.NTK[136.11]EPPLSLTIHLTSPVVR[166.11].E "sp|Q12906|ILF3_HUMAN,tr|K7EQR9|K7EQR9_HUMAN,tr|K7EKY0|K7EKY0_HUMAN,tr|K7EPG3|K7EPG3_HUMAN,tr|K7EKJ9|K7EKJ9_HUMAN" 5 2119.212 1.06 70393 19554 4 2119.20813 530.8103 Interleukin enhancer-binding factor 3 OS=Homo sapiens OX=9606 GN=ILF3 PE=1 SV=3 8.75 3249.9 - 601086 - - - -1.8304 - 3.878 0.534 - 332.1 1 2 1 -0.0039 19 0 0 0 6.37E+06 6.03E+06 - - - 4.3313 0.991 221125_WJC_METTL3_EV_vs_WT_F05.19556.19556.3 2.57E-09 13/80 R.MVAADNQDTSNLPQLAVPAPR[166.11].V "sp|Q8IWZ3|ANKH1_HUMAN,tr|A0A0A0MQZ8|A0A0A0MQZ8_HUMAN,tr|H0Y472|H0Y472_HUMAN,tr|H0Y7Y3|H0Y7Y3_HUMAN,tr|H0Y4P6|H0Y4P6_HUMAN,tr|H7C0V5|H7C0V5_HUMAN,tr|H0Y785|H0Y785_HUMAN" 7 2217.1087 1.72 70395 19556 3 2218.099799 740.0435 Ankyrin repeat and KH domain-containing protein 1 OS=Homo sapiens OX=9606 GN=ANKHD1 PE=1 SV=1 4.21 3250.2 - 330426 - - - 447.0069 - 2.38 0.662 - 147 1 2 0 0.9911 21 0 0 0 4.38E+07 2.55E+07 - - - 7.725 1 221125_WJC_METTL3_EV_vs_WT_F05.19559.19559.3 2.64E-12 20/80 R.GAHGIIVVYDVTDQESYANVK.Q sp|Q9H0U4|RAB1B_HUMAN 1 2277.1277 1.2 70396 19559 3 2277.127849 760.0499 Ras-related protein Rab-1B OS=Homo sapiens OX=9606 GN=RAB1B PE=1 SV=1 4.54 3250.6 - 1.74E+06 - - - 0.0536 - 3.479 0.646 - 531.2 1 2 0 0.0001 21 0 0 0 1.44E+07 1.20E+07 - - - 8.7312 1 221125_WJC_METTL3_EV_vs_WT_F05.19561.19561.3 1.71E-14 22/80 R.GAHGIIVVYDVTDQESYANVK[136.11].Q sp|Q9H0U4|RAB1B_HUMAN 1 2285.1419 1.19 70398 19561 3 2285.143393 762.7213 Ras-related protein Rab-1B OS=Homo sapiens OX=9606 GN=RAB1B PE=1 SV=1 4.54 3250.8 - 1.31E+06 - - - 0.6415 - 4.133 0.704 - 624.1 1 2 0 0.0015 21 0 0 0 1.42E+07 1.19E+07 - - - 9.7905 0.995 221125_WJC_METTL3_EV_vs_WT_F05.19563.19563.3 2.49E-06 Dec-96 R.AAASSYNTQGAASSLGSYGAQAASY.G sp|Q96PK6|RBM14_HUMAN 1 2353.0458 - 70400 19563 3 2353.041706 785.3559 RNA-binding protein 14 OS=Homo sapiens OX=9606 GN=RBM14 PE=1 SV=2 5.57 3251 - 543391 - - - -1.7603 - 2.649 0.509 - 101.3 1 1 0 -0.0041 25 0 0 0 - - - - - 6.4549 0.9999 221125_WJC_METTL3_EV_vs_WT_F05.19564.19564.2 1.06E-07 13/28 R.NHLLPDIVTC[160.03]VQSSR[166.11].K sp|Q9BSD7|NTPCR_HUMAN 1 1747.8915 1.12 70401 19564 2 1747.891551 874.953 Cancer-related nucleoside-triphosphatase OS=Homo sapiens OX=9606 GN=NTPCR PE=1 SV=1 6.74 3251.1 - 531966 - - - 0.0446 - 2.617 0.572 - 405.9 1 2 0 0.0001 15 0 0 0 1.69E+07 1.50E+07 - - - 5.631 1 221125_WJC_METTL3_EV_vs_WT_F05.19565.19565.3 0.000126 Dec-44 R.FATSEELLSHLR.T "sp|Q9H7S9|ZN703_HUMAN,sp|Q96F45|ZN503_HUMAN" 2 1401.7252 1.81 70402 19565 3 1401.725517 468.249 Zinc finger protein 703 OS=Homo sapiens OX=9606 GN=ZNF703 PE=1 SV=1 5.4 3251.3 - 496311 - - - 0.2055 - 2.271 0.47 - 97.8 1 2 0 0.0003 12 0 0 0 6.38E+06 3.52E+06 - - - 6.0535 1 221125_WJC_METTL3_EV_vs_WT_F05.19567.19567.3 5.11E-07 Nov-60 R.SWQDELAQQAEEGSAR.L sp|Q86UE4|LYRIC_HUMAN 1 1803.8024 1.05 70404 19567 3 1803.799579 602.2747 Protein LYRIC OS=Homo sapiens OX=9606 GN=MTDH PE=1 SV=2 4 3251.5 - 145480 - - - -1.5473 - 2.237 0.551 - 180.1 1 2 0 -0.0028 16 0 0 0 8.00E+06 7.59E+06 - - - 6.7482 1 221125_WJC_METTL3_EV_vs_WT_F05.19569.19569.3 7.90E-07 14/64 R.GAPPSSNIEDFHGLLPK[136.11].G "sp|P43243|MATR3_HUMAN,tr|A8MXP9|A8MXP9_HUMAN,tr|D6R991|D6R991_HUMAN,tr|A0A0R4J2E8|A0A0R4J2E8_HUMAN,tr|H0Y8T4|H0Y8T4_HUMAN,tr|D6REM6|D6REM6_HUMAN" 6 1785.9141 1.47 70405 19569 3 1785.910713 596.312 Matrin-3 OS=Homo sapiens OX=9606 GN=MATR3 PE=1 SV=2 5.32 3251.8 - 2.83E+07 - - - -1.8959 - 2.578 0.567 - 190.9 1 2 0 -0.0034 17 0 0 0 1.63E+09 1.11E+09 - - - 7.253 1 221125_WJC_METTL3_EV_vs_WT_F05.19571.19571.3 2.10E-06 18/64 R.QEQIDNQYHSLLELGEK.R tr|A0A0D9SF54|A0A0D9SF54_HUMAN 1 2042.9909 1.96 70406 19571 3 2042.990158 682.0042 "Spectrin alpha chain, non-erythrocytic 1 OS=Homo sapiens OX=9606 GN=SPTAN1 PE=1 SV=1" 4.4 3252 - 1.23E+06 - - - -0.3627 - 3.12 0.573 - 565.6 1 2 0 -0.0007 17 0 0 0 1.57E+07 8.05E+06 - - - 7.8027 0.9997 221125_WJC_METTL3_EV_vs_WT_F05.19572.19572.3 2.03E-10 20/88 R.GIYK[136.11]DDIAQVDYVEPSQNTISLK[136.11].M sp|O00267|SPT5H_HUMAN 1 2611.3352 0.95 70407 19572 3 2611.327104 871.4523 Transcription elongation factor SPT5 OS=Homo sapiens OX=9606 GN=SUPT5H PE=1 SV=1 4.23 3252.1 - 607419 - - - -3.1057 - 3.719 0.526 - 244.1 1 2 1 -0.0081 23 0 0 0 1.18E+07 1.25E+07 - - - 7.4834 1 221125_WJC_METTL3_EV_vs_WT_F05.19574.19574.3 0.00244 17/64 R.QEQIDNQYHSLLELGEK[136.11].R tr|A0A0D9SF54|A0A0D9SF54_HUMAN 1 2051.0051 1.87 70409 19574 3 2051.005122 684.6756 "Spectrin alpha chain, non-erythrocytic 1 OS=Homo sapiens OX=9606 GN=SPTAN1 PE=1 SV=1" 4.4 3252.3 - 848759 - - - 0.0112 - 3.023 0.479 - 414.8 1 2 0 0 17 0 0 0 1.51E+07 8.05E+06 - - - 6.6751 0.9998 221125_WJC_METTL3_EV_vs_WT_F05.19575.19575.3 6.18E-06 14/64 R.NNQGQLIAEPFYHLPSK[136.11].K "sp|Q86U86|PB1_HUMAN,tr|H0Y5B5|H0Y5B5_HUMAN,tr|E7EVG2|E7EVG2_HUMAN" 3 1963.0043 1.56 70410 19575 3 1963.000842 655.342 Protein polybromo-1 OS=Homo sapiens OX=9606 GN=PBRM1 PE=1 SV=1 6.75 3252.4 - 685063 - - - -1.7672 - 2.792 0.363 - 245.1 1 2 0 -0.0035 17 0 0 0 4.44E+07 2.84E+07 - - - 5.18 1 221125_WJC_METTL3_EV_vs_WT_F05.19576.19576.3 2.18E-07 20/64 R.NNQGQLIAEPFYHLPSK.K "sp|Q86U86|PB1_HUMAN,tr|H0Y5B5|H0Y5B5_HUMAN,tr|E7EVG2|E7EVG2_HUMAN" 3 1954.9901 1.56 70411 19576 3 1954.985702 652.6706 Protein polybromo-1 OS=Homo sapiens OX=9606 GN=PBRM1 PE=1 SV=1 6.75 3252.5 - 671141 - - - -2.2553 - 2.918 0.545 - 572.9 1 2 0 -0.0044 17 0 0 0 4.44E+07 2.84E+07 - - - 7.3204 0.9974 221125_WJC_METTL3_EV_vs_WT_F05.19577.19577.3 3.61E-08 16/80 R.YADLTEDQLPSC[160.03]ESLKDTIAR.A sp|P18669|PGAM1_HUMAN 1 2424.1479 2.23 70412 19577 3 2424.150004 809.0566 Phosphoglycerate mutase 1 OS=Homo sapiens OX=9606 GN=PGAM1 PE=1 SV=2 4.11 3252.6 - 536786 - - - 0.8803 - 2.98 0.233 - 221.7 1 2 1 0.0021 21 0 0 0 1.46E+07 6.53E+06 - - - 3.755 1 221125_WJC_METTL3_EV_vs_WT_F05.19579.19579.3 1.04E-06 17/44 R.FATSEELLSHLR[166.11].T "sp|Q9H7S9|ZN703_HUMAN,sp|Q96F45|ZN503_HUMAN" 2 1411.7335 1.81 70414 19579 3 1411.733593 471.5851 Zinc finger protein 703 OS=Homo sapiens OX=9606 GN=ZNF703 PE=1 SV=1 5.4 3252.9 - 413967 - - - 0.0666 - 2.798 0.55 - 280 1 2 0 0.0001 12 0 0 0 6.37E+06 3.52E+06 - - - 7.5239 0.9999 221125_WJC_METTL3_EV_vs_WT_F05.19582.19582.4 1.67E-05 13/108 R.VNVHGIFSVSSASLVEVHK[136.11].S "sp|P34932|HSP74_HUMAN,tr|A0A087WYC1|A0A087WYC1_HUMAN" 2 2016.0884 0.1 70417 19582 4 2016.085139 505.0294 Heat shock 70 kDa protein 4 OS=Homo sapiens OX=9606 GN=HSPA4 PE=1 SV=4 6.89 3253.3 - 193122 - - - -1.6051 - 2.291 0.462 - 73.8 1 2 0 -0.0032 19 0 0 0 9.12E+05 8.96E+06 - - - 3.5268 0.9996 221125_WJC_METTL3_EV_vs_WT_F05.19583.19583.3 0.0109 13/44 K.SQLDIIIHSLKK.C sp|P13010|XRCC5_HUMAN 1 1393.8293 0.87 70418 19583 3 1393.828169 465.617 X-ray repair cross-complementing protein 5 OS=Homo sapiens OX=9606 GN=XRCC5 PE=1 SV=3 8.33 3253.4 - 176892 - - - -0.8114 - 2.646 0.254 - 289.2 1 2 0 -0.0011 12 0 0 0 8.30E+06 9.52E+06 - - - 4.0687 1 221125_WJC_METTL3_EV_vs_WT_F05.19587.19587.3 2.17E-11 21/88 R.GIYKDDIAQVDYVEPSQNTISLK.M sp|O00267|SPT5H_HUMAN 1 2595.3068 0.95 70420 19587 3 2595.306066 866.1095 Transcription elongation factor SPT5 OS=Homo sapiens OX=9606 GN=SUPT5H PE=1 SV=1 4.23 3253.8 - 857634 - - - -0.2882 - 4.106 0.643 - 379.3 1 2 1 -0.0007 23 0 0 0 1.18E+07 1.25E+07 - - - 9.0221 1 221125_WJC_METTL3_EV_vs_WT_F05.19592.19592.3 1.73 16/64 K.VTEGLTDVILYHQPDDK.K "sp|O60506|HNRPQ_HUMAN,tr|A0A7I2YQV8|A0A7I2YQV8_HUMAN,tr|A0A7I2YQN2|A0A7I2YQN2_HUMAN,tr|A0A7I2V5Q6|A0A7I2V5Q6_HUMAN,tr|A0A7I2V4Z0|A0A7I2V4Z0_HUMAN,tr|B7Z645|B7Z645_HUMAN,tr|A0A7I2V2F2|A0A7I2V2F2_HUMAN,tr|A0A7I2V346|A0A7I2V346_HUMAN,tr|A0A7I2V309|A0A7I2V309_HUMAN" 9 1941.9684 1.68 70425 19592 3 1941.967162 648.3301 Heterogeneous nuclear ribonucleoprotein Q OS=Homo sapiens OX=9606 GN=SYNCRIP PE=1 SV=2 4.22 3254.4 - 514736 - - - -0.6236 - 3.147 0.472 - 352.2 1 2 0 -0.0012 17 0 0 0 7.06E+06 4.21E+06 - - - 6.6983 0.9999 221125_WJC_METTL3_EV_vs_WT_F05.19594.19594.3 1.29E-09 15/80 R.YADLTEDQLPSC[160.03]ESLK[136.11]DTIAR[166.11].A sp|P18669|PGAM1_HUMAN 1 2442.1703 2.21 70427 19594 3 2442.169839 815.0641 Phosphoglycerate mutase 1 OS=Homo sapiens OX=9606 GN=PGAM1 PE=1 SV=2 4.11 3254.7 - 486299 - - - -0.2051 - 2.893 0.576 - 187 1 2 1 -0.0005 21 0 0 0 1.43E+07 6.46E+06 - - - 7.5085 0.9982 221125_WJC_METTL3_EV_vs_WT_F05.19595.19595.3 0.00295 Oct-64 R.ITFDAFPGEPDKELNPK.K sp|Q12904|AIMP1_HUMAN 1 1916.952 1.6 70428 19595 3 1916.955766 639.9913 Aminoacyl tRNA synthase complex-interacting multifunctional protein 1 OS=Homo sapiens OX=9606 GN=AIMP1 PE=1 SV=2 4.32 3254.8 - 382255 - - - 1.9677 - 1.93 0.389 - 114.7 1 2 1 0.0038 17 0 0 0 5.48E+06 3.43E+06 - - - 4.537 1 221125_WJC_METTL3_EV_vs_WT_F05.19597.19597.2 1.96E-12 15/30 R.SWQDELAQQAEEGSAR.L sp|Q86UE4|LYRIC_HUMAN 1 1803.8024 1.54 70430 19597 2 1803.801013 902.9085 Protein LYRIC OS=Homo sapiens OX=9606 GN=MTDH PE=1 SV=2 4 3255.1 - 208029 - - - -0.7523 - 2.674 0.706 - 445 1 2 0 -0.0014 16 0 0 0 2.44E+06 1.59E+06 - - - 6.6733 1 221125_WJC_METTL3_EV_vs_WT_F05.19601.19601.3 5.48E-06 14/44 K.SQLDIIIHSLK[136.11]K[136.11].C sp|P13010|XRCC5_HUMAN 1 1409.8577 0.87 70432 19601 3 1409.858505 470.9598 X-ray repair cross-complementing protein 5 OS=Homo sapiens OX=9606 GN=XRCC5 PE=1 SV=3 8.33 3255.6 - 759496 - - - 0.571 - 2.711 0.561 - 289.5 1 2 0 0.0008 12 0 0 0 8.30E+06 9.52E+06 - - - 7.5588 1 221125_WJC_METTL3_EV_vs_WT_F05.19602.19602.3 1.09E-07 18/72 K.DAGEGLLAVQITDPEGKPK.K "sp|P21333|FLNA_HUMAN,tr|Q60FE5|Q60FE5_HUMAN" 2 1937.0106 1.51 70433 19602 3 1937.014542 646.6775 Filamin-A OS=Homo sapiens OX=9606 GN=FLNA PE=1 SV=4 4.32 3255.8 - 573032 - - - 2.0495 - 3.256 0.532 - 327 1 2 0 0.004 19 0 0 0 1.72E+07 1.14E+07 - - - 7.3704 1 221125_WJC_METTL3_EV_vs_WT_F05.19603.19603.3 4.34E-10 17/60 K.FR[166.11]QDLMNIAGTTLSSK[136.11].L "sp|P78371|TCPB_HUMAN,tr|F8VQ14|F8VQ14_HUMAN,tr|F5GWF6|F5GWF6_HUMAN" 3 1798.9366 3.24 70434 19603 3 1798.937066 600.6528 T-complex protein 1 subunit beta OS=Homo sapiens OX=9606 GN=CCT2 PE=1 SV=4 8.75 3255.8 - 2.25E+06 - - - 0.2374 - 3.324 0.606 - 431.2 1 2 1 0.0004 16 0 0 0 1.52E+08 4.68E+07 - - - 8.3782 0.9956 221125_WJC_METTL3_EV_vs_WT_F05.19606.19606.3 0.0413 Jul-60 R.C[160.03]IPALDSLTPANEDQK.L "sp|P10809|CH60_HUMAN,tr|A0A7I2V2X6|A0A7I2V2X6_HUMAN,tr|A0A7I2YQK6|A0A7I2YQK6_HUMAN,tr|A0A7I2V599|A0A7I2V599_HUMAN" 4 1770.8458 999 70437 19606 3 1770.842592 591.2892 "60 kDa heat shock protein, mitochondrial OS=Homo sapiens OX=9606 GN=HSPD1 PE=1 SV=2" 4.03 3256.2 - 404646 - - - -1.82 - 1.711 0.242 - 50.2 1 2 0 -0.0032 16 0 0 0 1.08E+07 0.00E+00 - - - 2.6152 0.9999 221125_WJC_METTL3_EV_vs_WT_F05.19610.19610.3 0.000416 15/68 R.ASWESLDEEWRAPQAGSR.T sp|Q00587|BORG5_HUMAN 1 2073.9504 1.08 70439 19610 3 2073.950983 692.3241 Cdc42 effector protein 1 OS=Homo sapiens OX=9606 GN=CDC42EP1 PE=1 SV=1 4.41 3256.8 - 272760 - - - 0.2662 - 2.708 0.532 - 255.2 1 2 1 0.0006 18 0 0 0 2.71E+06 2.52E+06 - - - 6.9518 1 221125_WJC_METTL3_EV_vs_WT_F05.19614.19614.3 3.06E-13 17/96 K.NLDPDPEPPSPDSPTETFAAPAEVR.H "sp|Q9BUA3|SPNDC_HUMAN,tr|H0YGY5|H0YGY5_HUMAN" 2 2648.2242 5.87 70443 19614 3 2648.222609 883.7487 Spindlin interactor and repressor of chromatin-binding protein OS=Homo sapiens OX=9606 GN=SPINDOC PE=1 SV=3 3.71 3257.3 - 382372 - - - -0.603 - 3.43 0.721 - 238.9 1 2 0 -0.0016 25 0 0 0 6.85E+06 1.17E+06 - - - 9.4137 0.9974 221125_WJC_METTL3_EV_vs_WT_F05.19617.19617.3 3.52E-07 Dec-88 R.LK[136.11]DLNSQADSLMTSSAFDTSQVK[136.11].D "sp|Q13813|SPTN1_HUMAN,tr|A0A0D9SF54|A0A0D9SF54_HUMAN,tr|A0A0D9SGF6|A0A0D9SGF6_HUMAN" 3 2501.229 1.36 70446 19617 3 2502.233065 834.7503 "Spectrin alpha chain, non-erythrocytic 1 OS=Homo sapiens OX=9606 GN=SPTAN1 PE=1 SV=3" 4.43 3257.7 - 219001 - - - 401.4151 - 2.787 0.559 - 174.2 1 2 1 1.004 23 0 0 0 2.74E+06 2.01E+06 - - - 6.8987 1 221125_WJC_METTL3_EV_vs_WT_F05.19621.19621.3 3.27E-08 14/100 R.EPAPAEALPQQYPEPAPAALC[160.03]GPPPR.A sp|Q8IU81|I2BP1_HUMAN 1 2723.3377 2.27 70448 19621 3 2723.340018 908.7865 Interferon regulatory factor 2-binding protein 1 OS=Homo sapiens OX=9606 GN=IRF2BP1 PE=1 SV=1 4.25 3258.2 - 340815 - - - 0.8376 - 2.608 0.563 - 137.1 1 2 0 0.0023 26 0 0 0 6.28E+06 2.77E+06 - - - 7.0216 0.9996 221125_WJC_METTL3_EV_vs_WT_F05.19623.19623.3 8.61E-08 14/88 R.LKDLNSQADSLMTSSAFDTSQVK.D "sp|Q13813|SPTN1_HUMAN,tr|A0A0D9SF54|A0A0D9SF54_HUMAN,tr|A0A0D9SGF6|A0A0D9SGF6_HUMAN" 3 2485.2006 1.36 70450 19623 3 2485.204641 829.4075 "Spectrin alpha chain, non-erythrocytic 1 OS=Homo sapiens OX=9606 GN=SPTAN1 PE=1 SV=3" 4.43 3258.5 - 297886 - - - 1.6123 - 3.039 0.408 - 187.4 1 2 1 0.004 23 0 0 0 2.74E+06 2.01E+06 - - - 5.6953 0.9998 221125_WJC_METTL3_EV_vs_WT_F05.19633.19633.2 0.00639 28-Oct R.NHLLPDIVTC[160.03]VQSSR.K sp|Q9BSD7|NTPCR_HUMAN 1 1737.8832 1.12 70458 19633 2 1737.88461 869.9489 Cancer-related nucleoside-triphosphatase OS=Homo sapiens OX=9606 GN=NTPCR PE=1 SV=1 6.74 3259.7 - 329379 - - - 0.8096 - 2.235 0.442 - 205.3 1 2 0 0.0014 15 0 0 0 1.69E+07 1.50E+07 - - - 4.2824 1 221125_WJC_METTL3_EV_vs_WT_F05.19634.19634.3 2.46E-07 16/76 K.DLLLTSSYLSDSGSTGEHTK[136.11].S "sp|P08195|4F2_HUMAN,tr|A0A7P0TAN7|A0A7P0TAN7_HUMAN,tr|J3KPF3|J3KPF3_HUMAN,tr|F5H056|F5H056_HUMAN,tr|F5GZI0|F5GZI0_HUMAN,tr|A0A7P0T8U7|A0A7P0T8U7_HUMAN,tr|A0A7P0T9F7|A0A7P0T9F7_HUMAN,tr|A0A7P0TBF8|A0A7P0TBF8_HUMAN,tr|A0A7P0T8F1|A0A7P0T8F1_HUMAN,tr|H0YFX4|H0YFX4_HUMAN,tr|A0A7P0Z4A0|A0A7P0Z4A0_HUMAN,tr|F5GZS6|F5GZS6_HUMAN,tr|A0A7P0Z4P5|A0A7P0Z4P5_HUMAN,tr|A0A7P0TAS6|A0A7P0TAS6_HUMAN" 14 2118.0208 1.15 70459 19634 3 2118.021815 707.0142 4F2 cell-surface antigen heavy chain OS=Homo sapiens OX=9606 GN=SLC3A2 PE=1 SV=3 4.54 3259.8 - 367080 - - - 0.475 - 2.92 0.584 - 204.5 1 2 0 0.001 20 0 0 0 8.02E+06 6.96E+06 - - - 7.6504 0.9992 221125_WJC_METTL3_EV_vs_WT_F05.19636.19636.3 0.0025 Nov-60 K.QDYDLMVFPESDSQK[136.11]R[166.11].A "sp|O00443|P3C2A_HUMAN,tr|A0A0C4DGF9|A0A0C4DGF9_HUMAN,tr|E9PPP3|E9PPP3_HUMAN" 3 1974.9112 1.29 70461 19636 3 1974.915508 659.311 Phosphatidylinositol 4-phosphate 3-kinase C2 domain-containing subunit alpha OS=Homo sapiens OX=9606 GN=PIK3C2A PE=1 SV=2 4.23 3260.1 - 352076 - - - 2.1753 - 2.054 0.326 - 171.3 1 2 0 0.0043 16 0 0 0 1.07E+07 8.31E+06 - - - 4.0203 1 221125_WJC_METTL3_EV_vs_WT_F05.19637.19637.3 5.76E-06 Nov-44 K.GTNYLADVFEKK.D sp|P31151|S10A7_HUMAN 1 1383.7034 2.11 70462 19637 3 1383.704593 462.2418 Protein S100-A7 OS=Homo sapiens OX=9606 GN=S100A7 PE=1 SV=4 6.07 3260.2 - 303635 - - - 0.8398 - 1.9 0.551 - 140.7 1 2 0 0.0012 12 0 0 0 5.98E+06 2.83E+06 - - - 6.4619 1 221125_WJC_METTL3_EV_vs_WT_F05.19639.19639.3 1.42E-08 13/72 R.VNVHGIFSVSSASLVEVHK[136.11].S "sp|P34932|HSP74_HUMAN,tr|A0A087WYC1|A0A087WYC1_HUMAN" 2 2016.0884 0.001 70464 19639 3 2016.086931 673.0367 Heat shock 70 kDa protein 4 OS=Homo sapiens OX=9606 GN=HSPA4 PE=1 SV=4 6.89 3260.5 - 162840 - - - -0.7162 - 3.014 0.563 - 253.5 1 2 0 -0.0014 19 0 0 0 0.00E+00 1.69E+06 - - - 7.527 1 221125_WJC_METTL3_EV_vs_WT_F05.19644.19644.3 7.41E-08 13/88 K.ASK[136.11]PLPPAPAPDEYLVSPITGEK[136.11].L "sp|Q15459|SF3A1_HUMAN,tr|H7C1L2|H7C1L2_HUMAN" 2 2392.2861 1.27 70468 19644 3 2392.287524 798.436 Splicing factor 3A subunit 1 OS=Homo sapiens OX=9606 GN=SF3A1 PE=1 SV=1 4.68 3261.1 - 245153 - - - 0.6044 - 2.708 0.626 - 146.1 1 2 0 0.0014 23 0 0 0 5.71E+07 4.51E+07 - - - 7.8559 0.9974 221125_WJC_METTL3_EV_vs_WT_F05.19646.19646.3 0.00196 Oct-64 K.DSQFLVSSVTDDDFGKK.D sp|Q6ZNB6|NFXL1_HUMAN 1 1886.8898 0.72 70469 19646 3 1886.897231 629.9705 NF-X1-type zinc finger protein NFXL1 OS=Homo sapiens OX=9606 GN=NFXL1 PE=1 SV=2 4.14 3261.3 - 317734 - - - 3.9446 - 1.704 0.38 - 48.4 1 2 0 0.0074 17 0 0 0 4.39E+06 6.08E+06 - - - 4.121 1 221125_WJC_METTL3_EV_vs_WT_F05.19647.19647.3 8.62E-07 15/44 R.RHPDYSVVLLLR.L "sp|P02768|ALBU_HUMAN,tr|B7WNR0|B7WNR0_HUMAN,tr|H0YA55|H0YA55_HUMAN,tr|A0A0C4DGB6|A0A0C4DGB6_HUMAN,tr|D6RHD5|D6RHD5_HUMAN,tr|C9JKR2|C9JKR2_HUMAN" 6 1466.8358 999 70470 19647 3 1466.838437 489.9525 Albumin OS=Homo sapiens OX=9606 GN=ALB PE=1 SV=2 8.75 3261.5 - 335105 - - - 1.8093 - 3.27 0.567 - 530.1 1 2 0 0.0027 12 0 0 0 5.34E+06 0.00E+00 - - - 8.1448 1 221125_WJC_METTL3_EV_vs_WT_F05.19648.19648.4 8.41E-07 10/138 R.ISGETIFVTAPHEATAGIIGVNRK.G "sp|Q00610|CLH1_HUMAN,tr|A0A087WVQ6|A0A087WVQ6_HUMAN" 2 2480.3387 0.95 70471 19648 4 2480.343076 621.092 Clathrin heavy chain 1 OS=Homo sapiens OX=9606 GN=CLTC PE=1 SV=5 6.76 3261.6 - 262608 - - - 1.755 - 2.411 0.523 - 44.2 1 2 0 0.0044 24 0 0 0 5.34E+06 5.64E+06 - - - 4.0594 0.9998 221125_WJC_METTL3_EV_vs_WT_F05.19650.19650.3 9.88E-06 Aug-68 K.DDANNDPQWSEEQLIAAK[136.11].F "sp|P22234|PUR6_HUMAN,tr|D6RF62|D6RF62_HUMAN,tr|E9PBS1|E9PBS1_HUMAN" 3 2050.9323 0.73 70473 19650 3 2050.937041 684.6514 Multifunctional protein ADE2 OS=Homo sapiens OX=9606 GN=PAICS PE=1 SV=3 3.77 3261.9 - 137928 - - - 2.298 - 1.644 0.51 - 61.1 1 2 0 0.0047 18 0 0 0 1.17E+06 1.62E+06 - - - 5.4626 0.9996 221125_WJC_METTL3_EV_vs_WT_F05.19654.19654.3 3.60E-09 16/64 K.DSQFLVSSVTDDDFGK[136.11]K[136.11].D sp|Q6ZNB6|NFXL1_HUMAN 1 1902.9182 0.72 70475 19654 3 1903.920345 635.3133 NF-X1-type zinc finger protein NFXL1 OS=Homo sapiens OX=9606 GN=NFXL1 PE=1 SV=2 4.14 3262.4 - 412634 - - - 526.6422 - 2.924 0.596 - 239.1 1 2 0 1.0022 17 0 0 0 4.39E+06 6.08E+06 - - - 7.6178 0.9999 221125_WJC_METTL3_EV_vs_WT_F05.19656.19656.4 2.14E-07 15/120 R.AINVLLEGNPDTHSWEMVGK[136.11]K[136.11].K "sp|Q14157|UBP2L_HUMAN,tr|Q5VU78|Q5VU78_HUMAN,tr|F8W726|F8W726_HUMAN,tr|Q5VU81|Q5VU81_HUMAN,tr|Q5VU79|Q5VU79_HUMAN,tr|Q5VU80|Q5VU80_HUMAN,tr|Q5VU77|Q5VU77_HUMAN" 7 2353.2071 2.14 70477 19656 4 2353.214181 589.3091 Ubiquitin-associated protein 2-like OS=Homo sapiens OX=9606 GN=UBAP2L PE=1 SV=2 5.45 3262.7 - 403379 - - - 3.0019 - 2.783 0.537 - 174.8 1 2 0 0.0071 21 0 0 0 1.06E+07 4.94E+06 - - - 4.2365 0.9981 221125_WJC_METTL3_EV_vs_WT_F05.19657.19657.3 1.04E-05 13/76 K.EAGTKEEPVTADVINPMALR.Q sp|O43290|SNUT1_HUMAN 1 2140.0834 2.36 70478 19657 3 2140.092699 714.3684 U4\U6.U5 tri-snRNP-associated protein 1 OS=Homo sapiens OX=9606 GN=SART1 PE=1 SV=1 4.41 3262.8 - 278083 - - - 4.3363 - 2.606 0.475 - 126.9 1 2 1 0.0093 20 0 0 0 5.63E+06 2.39E+06 - - - 6.1569 0.9994 221125_WJC_METTL3_EV_vs_WT_F05.19662.19662.3 0.00604 Oct-60 K.KQC[160.03]ANLQNAIADAEQR.G "sp|P13647|K2C5_HUMAN,tr|H0YI76|H0YI76_HUMAN" 2 1828.885 21.37 70483 19662 3 1828.888203 610.6356 "Keratin, type II cytoskeletal 5 OS=Homo sapiens OX=9606 GN=KRT5 PE=1 SV=3" 6.06 3263.4 - 160925 - - - 1.7546 - 1.917 0.343 - 74.4 1 2 0 0.0032 16 0 0 0 2.33E+06 1.09E+05 - - - 4.033 1 221125_WJC_METTL3_EV_vs_WT_F05.19663.19663.2 2.35E-06 28-Oct R.SSDSWEVWGSASTNR.N "sp|Q8N6T3|ARFG1_HUMAN,tr|F8VWH9|F8VWH9_HUMAN,tr|E5RHH7|E5RHH7_HUMAN" 3 1667.7176 1.85 70484 19663 2 1667.723505 834.8661 ADP-ribosylation factor GTPase-activating protein 1 OS=Homo sapiens OX=9606 GN=ARFGAP1 PE=1 SV=2 4.37 3263.6 - 145239 - - - 3.554 - 2.401 0.626 - 268.9 1 2 0 0.0059 15 0 0 0 3.82E+06 2.06E+06 - - - 5.8162 1 221125_WJC_METTL3_EV_vs_WT_F05.19664.19664.2 3.76E-12 Dec-40 R.MVAADNQDTSNLPQLAVPAPR.V "sp|Q8IWZ3|ANKH1_HUMAN,tr|A0A0A0MQZ8|A0A0A0MQZ8_HUMAN,tr|H0Y472|H0Y472_HUMAN,tr|H0Y7Y3|H0Y7Y3_HUMAN,tr|H0Y4P6|H0Y4P6_HUMAN,tr|H7C0V5|H7C0V5_HUMAN,tr|H0Y785|H0Y785_HUMAN" 7 2207.1005 1.92 70485 19664 2 2207.10358 1104.5575 Ankyrin repeat and KH domain-containing protein 1 OS=Homo sapiens OX=9606 GN=ANKHD1 PE=1 SV=1 4.21 3263.7 - 114888 - - - 1.4109 - 2.739 0.711 - 228.2 1 2 0 0.0031 21 0 0 0 2.70E+06 1.40E+06 - - - 6.7687 0.8782 221125_WJC_METTL3_EV_vs_WT_F05.19668.19668.2 0.0521 26-Jun K.NQSQGYNQWQQGQF.W "sp|Q00839|HNRPU_HUMAN,tr|A0A1W2PPL4|A0A1W2PPL4_HUMAN,tr|Q5RI18|Q5RI18_HUMAN,tr|A0A1W2PP35|A0A1W2PP35_HUMAN,tr|A0A1W2PPH7|A0A1W2PPH7_HUMAN,tr|A0A1X7SBS1|A0A1X7SBS1_HUMAN" 6 1711.7339 - 70487 19668 2 1711.737146 856.8742 Heterogeneous nuclear ribonucleoprotein U OS=Homo sapiens OX=9606 GN=HNRNPU PE=1 SV=6 5.52 3264.3 - 329082 - - - 1.8987 - 1.366 0.338 - 77.8 1 1 0 0.0032 14 0 0 0 - - - - - 2.3191 0.9999 221125_WJC_METTL3_EV_vs_WT_F05.19669.19669.3 1.50E-05 Oct-80 K.VGIFNC[160.03]HGMGGNQVFSYTANK.E sp|Q10472|GALT1_HUMAN 1 2300.0467 1.1 70488 19669 3 2300.051943 767.6895 Polypeptide N-acetylgalactosaminyltransferase 1 OS=Homo sapiens OX=9606 GN=GALNT1 PE=1 SV=1 8.18 3264.4 - 215144 - - - 2.2982 - 2.109 0.548 - 89.1 1 2 0 0.0053 21 0 0 0 2.98E+06 2.71E+06 - - - 6.4372 1 221125_WJC_METTL3_EV_vs_WT_F05.19670.19670.3 5.57E-13 23/64 K.HGEPEEDIVGLQAFQER[166.11].L "sp|O75694|NU155_HUMAN,tr|E9PF10|E9PF10_HUMAN" 2 1962.9311 1.74 70489 19670 3 1962.935479 655.3176 Nuclear pore complex protein Nup155 OS=Homo sapiens OX=9606 GN=NUP155 PE=1 SV=1 4.25 3264.5 - 676673 - - - 2.2365 - 3.887 0.64 - 960.3 1 2 0 0.0044 17 0 0 0 2.42E+07 1.40E+07 - - - 9.104 0.967 221125_WJC_METTL3_EV_vs_WT_F05.19672.19672.3 0.00228 Sep-72 K.NTKEPPLSLTIHLTSPVVR.E "sp|Q12906|ILF3_HUMAN,tr|K7EQR9|K7EQR9_HUMAN,tr|K7EKY0|K7EKY0_HUMAN,tr|K7EPG3|K7EPG3_HUMAN,tr|K7EKJ9|K7EKJ9_HUMAN" 5 2101.1895 1.63 70491 19672 3 2101.198169 701.4038 Interleukin enhancer-binding factor 3 OS=Homo sapiens OX=9606 GN=ILF3 PE=1 SV=3 8.75 3264.8 - 90738.7 - - - 4.1072 - 1.498 0.349 - 62.1 1 2 1 0.0086 19 0 0 0 1.74E+06 1.07E+06 - - - 3.4215 0.9998 221125_WJC_METTL3_EV_vs_WT_F05.19674.19674.3 2.77E-06 13/64 R.GAPPSSNIEDFHGLLPK.G "sp|P43243|MATR3_HUMAN,tr|A8MXP9|A8MXP9_HUMAN,tr|D6R991|D6R991_HUMAN,tr|A0A0R4J2E8|A0A0R4J2E8_HUMAN,tr|H0Y8T4|H0Y8T4_HUMAN,tr|D6REM6|D6REM6_HUMAN" 6 1777.8999 1.43 70492 19674 3 1777.906532 593.6406 Matrin-3 OS=Homo sapiens OX=9606 GN=MATR3 PE=1 SV=2 5.32 3265 - 8.19E+06 - - - 3.7308 - 2.449 0.511 - 166.2 1 2 0 0.0066 17 0 0 0 1.64E+09 1.15E+09 - - - 6.4981 0.9998 221125_WJC_METTL3_EV_vs_WT_F05.19676.19676.4 2.61E-06 14/120 R.AINVLLEGNPDTHSWEMVGKK.K "sp|Q14157|UBP2L_HUMAN,tr|Q5VU78|Q5VU78_HUMAN,tr|F8W726|F8W726_HUMAN,tr|Q5VU81|Q5VU81_HUMAN,tr|Q5VU79|Q5VU79_HUMAN,tr|Q5VU80|Q5VU80_HUMAN,tr|Q5VU77|Q5VU77_HUMAN" 7 2337.1787 1.68 70494 19676 4 2337.188375 585.302 Ubiquitin-associated protein 2-like OS=Homo sapiens OX=9606 GN=UBAP2L PE=1 SV=2 5.45 3265.2 - 1.20E+06 - - - 4.1323 - 2.6 0.516 - 97.2 1 2 0 0.0097 21 0 0 0 1.09E+07 6.50E+06 - - - 4.0305 0.9992 221125_WJC_METTL3_EV_vs_WT_F05.19677.19677.3 6.31E-07 16/64 K.AGTQIENIDEDFR[166.11]DGLK[136.11].L "sp|O43707|ACTN4_HUMAN,tr|F5GXS2|F5GXS2_HUMAN,tr|K7EP19|K7EP19_HUMAN,tr|H7C144|H7C144_HUMAN" 4 1937.945 1.53 70495 19677 3 1937.948011 646.9889 Alpha-actinin-4 OS=Homo sapiens OX=9606 GN=ACTN4 PE=1 SV=2 4.11 3265.3 - 701888 - - - 1.5769 - 2.915 0.347 - 269 1 2 1 0.0031 17 0 0 0 1.15E+07 7.50E+06 - - - 5.1107 0.9991 221125_WJC_METTL3_EV_vs_WT_F05.19681.19681.2 0.00317 Aug-34 K.VGINYQPPTVVPGGDLAK[136.11].V "sp|Q9NY65|TBA8_HUMAN,sp|Q6PEY2|TBA3E_HUMAN,sp|P0DPH7|TBA3C_HUMAN,sp|Q71U36|TBA1A_HUMAN,sp|P0DPH8|TBA3D_HUMAN,sp|P68366|TBA4A_HUMAN,sp|P68363|TBA1B_HUMAN,sp|Q9BQE3|TBA1C_HUMAN,tr|A0A1W2PQM2|A0A1W2PQM2_HUMAN,tr|F5H5D3|F5H5D3_HUMAN,tr|C9J2C0|C9J2C0_HUMAN,tr|V9GZ17|V9GZ17_HUMAN,tr|A0A7P0T945|A0A7P0T945_HUMAN" 13 1831.9923 0.51 70499 19681 2 1831.994789 917.0035 Tubulin alpha-8 chain OS=Homo sapiens OX=9606 GN=TUBA8 PE=1 SV=1 5.81 3265.8 - 143763 - - - 1.3319 - 1.408 0.41 - 128.7 1 2 0 0.0024 18 0 0 0 1.06E+06 2.07E+06 - - - 2.9097 1 221125_WJC_METTL3_EV_vs_WT_F05.19683.19683.3 2.60E-06 21/80 R.MVAADNQDTSNLPQLAVPAPR.V "sp|Q8IWZ3|ANKH1_HUMAN,tr|A0A0A0MQZ8|A0A0A0MQZ8_HUMAN,tr|H0Y472|H0Y472_HUMAN,tr|H0Y7Y3|H0Y7Y3_HUMAN,tr|H0Y4P6|H0Y4P6_HUMAN,tr|H7C0V5|H7C0V5_HUMAN,tr|H0Y785|H0Y785_HUMAN" 7 2207.1005 1.71 70500 19683 3 2207.106202 736.7074 Ankyrin repeat and KH domain-containing protein 1 OS=Homo sapiens OX=9606 GN=ANKHD1 PE=1 SV=1 4.21 3266.1 - 1.30E+06 - - - 2.5989 - 3.158 0.576 - 421.1 1 2 0 0.0057 21 0 0 0 4.36E+07 2.55E+07 - - - 7.7172 1 221125_WJC_METTL3_EV_vs_WT_F05.19685.19685.3 2.60E-09 20/64 K.HGEPEEDIVGLQAFQER.L "sp|O75694|NU155_HUMAN,tr|E9PF10|E9PF10_HUMAN" 2 1952.9228 1.74 70501 19685 3 1952.930066 651.9815 Nuclear pore complex protein Nup155 OS=Homo sapiens OX=9606 GN=NUP155 PE=1 SV=1 4.25 3266.3 - 1.24E+06 - - - 3.7108 - 3.938 0.653 - 652.9 1 2 0 0.0072 17 0 0 0 2.42E+07 1.40E+07 - - - 9.281 1 221125_WJC_METTL3_EV_vs_WT_F05.19687.19687.3 4.07E-15 22/72 K.C[160.03]NLHMNGNVITSDQPILLR.L "sp|Q9BY77|PDIP3_HUMAN,tr|F6VRR5|F6VRR5_HUMAN" 2 2194.0987 0.36 70503 19687 3 2194.106901 732.3735 Polymerase delta-interacting protein 3 OS=Homo sapiens OX=9606 GN=POLDIP3 PE=1 SV=2 6.74 3266.6 - 797105 - - - 3.7414 - 4.097 0.729 - 704.5 1 2 0 0.0082 19 0 0 0 1.00E+07 2.78E+07 - - - 10.1301 0.9999 221125_WJC_METTL3_EV_vs_WT_F05.19691.19691.3 0.000179 Oct-52 R.KVEFLEDFGSDVNK.L sp|Q86UA1|PRP39_HUMAN 1 1625.7937 1.74 70507 19691 3 1625.799343 542.9385 Pre-mRNA-processing factor 39 OS=Homo sapiens OX=9606 GN=PRPF39 PE=1 SV=3 4.32 3267.1 - 183193 - - - 3.4691 - 2.257 0.531 - 95.4 1 2 0 0.0056 14 0 0 0 3.66E+06 2.10E+06 - - - 6.6219 0.9995 221125_WJC_METTL3_EV_vs_WT_F05.19693.19693.3 0.000267 Jun-80 R.NFTMDTESSVYNFEGEDYR[166.11]EK[136.11].Q sp|O60264|SMCA5_HUMAN 1 2578.0925 0.44 70509 19693 3 2578.098727 860.3714 SWI\SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A member 5 OS=Homo sapiens OX=9606 GN=SMARCA5 PE=1 SV=1 4.08 3267.4 - 118211 - - - 2.4216 - 1.537 0.588 - 30.7 1 2 1 0.0062 21 0 0 0 5.55E+05 1.26E+06 - - - 6.1244 0.998 221125_WJC_METTL3_EV_vs_WT_F05.19694.19694.3 6.00E-05 Oct-88 R.EESLEK[136.11]EPEYVPWTATSGPGGIR[166.11].T sp|Q8WUM0|NU133_HUMAN 1 2549.2405 1.96 70510 19694 3 2549.250463 850.7541 Nuclear pore complex protein Nup133 OS=Homo sapiens OX=9606 GN=NUP133 PE=1 SV=2 4.33 3267.5 - 105050 - - - 3.9204 - 2.13 0.487 - 96.8 1 2 1 0.01 23 0 0 0 1.76E+06 9.02E+05 - - - 5.7406 0.8782 221125_WJC_METTL3_EV_vs_WT_F05.19695.19695.2 0.0223 Jul-34 K.VGINYQPPTVVPGGDLAK.V "sp|Q9NY65|TBA8_HUMAN,sp|Q6PEY2|TBA3E_HUMAN,sp|P0DPH7|TBA3C_HUMAN,sp|Q71U36|TBA1A_HUMAN,sp|P0DPH8|TBA3D_HUMAN,sp|P68366|TBA4A_HUMAN,sp|P68363|TBA1B_HUMAN,sp|Q9BQE3|TBA1C_HUMAN,tr|A0A1W2PQM2|A0A1W2PQM2_HUMAN,tr|F5H5D3|F5H5D3_HUMAN,tr|C9J2C0|C9J2C0_HUMAN,tr|V9GZ17|V9GZ17_HUMAN,tr|A0A7P0T945|A0A7P0T945_HUMAN" 13 1823.9781 0.51 70511 19695 2 1823.985577 912.9964 Tubulin alpha-8 chain OS=Homo sapiens OX=9606 GN=TUBA8 PE=1 SV=1 5.81 3267.6 - 95977.7 - - - 4.0724 - 1.202 0.125 - 98.2 1 2 0 0.0074 18 0 0 0 1.06E+06 2.07E+06 - - - 0.4143 1 221125_WJC_METTL3_EV_vs_WT_F05.19705.19705.3 8.70E-06 13/88 R.APYPFAVENQNEAENTIQNEAQR.- sp|Q9HBI5|CC014_HUMAN 1 2632.2154 5.81 70519 19705 3 2632.223262 878.4124 Uncharacterized protein C3orf14 OS=Homo sapiens OX=9606 GN=C3orf14 PE=2 SV=1 4.09 3268.9 - 249623 - - - 2.9971 - 3.096 0.62 - 116.8 1 2 0 0.0079 23 0 0 0 4.04E+06 6.96E+05 - - - 8.1014 1 221125_WJC_METTL3_EV_vs_WT_F05.19707.19707.2 3.17E-10 14/42 R.SSGAPAPGSGATIFALSSGQGR.C "sp|Q969Y2|GTPB3_HUMAN,tr|M0R0S9|M0R0S9_HUMAN,tr|M0R1X0|M0R1X0_HUMAN" 3 1974.9759 2.24 70521 19707 2 1974.982192 988.4952 "tRNA modification GTPase GTPBP3, mitochondrial OS=Homo sapiens OX=9606 GN=GTPBP3 PE=1 SV=2" 9.47 3269.2 - 214767 - - - 3.1767 - 3.314 0.688 - 362.1 1 2 0 0.0063 22 0 0 0 6.55E+06 2.92E+06 - - - 7.0663 1 221125_WJC_METTL3_EV_vs_WT_F05.19710.19710.2 7.13E-11 13/42 R.SSGAPAPGSGATIFALSSGQGR[166.11].C "sp|Q969Y2|GTPB3_HUMAN,tr|M0R0S9|M0R0S9_HUMAN,tr|M0R1X0|M0R1X0_HUMAN" 3 1984.9842 2.24 70524 19710 2 1984.987224 993.4994 "tRNA modification GTPase GTPBP3, mitochondrial OS=Homo sapiens OX=9606 GN=GTPBP3 PE=1 SV=2" 9.47 3269.6 - 120029 - - - 1.5295 - 2.851 0.705 - 307.1 1 2 0 0.003 22 0 0 0 6.55E+06 2.92E+06 - - - 6.8229 0.9996 221125_WJC_METTL3_EV_vs_WT_F05.19711.19711.2 0.00383 28-May R.SSDSWEVWGSASTNR[166.11].N "sp|Q8N6T3|ARFG1_HUMAN,tr|F8VWH9|F8VWH9_HUMAN,tr|E5RHH7|E5RHH7_HUMAN" 3 1677.7258 1.85 70525 19711 2 1677.725 839.8702 ADP-ribosylation factor GTPase-activating protein 1 OS=Homo sapiens OX=9606 GN=ARFGAP1 PE=1 SV=2 4.37 3269.7 - 118676 - - - -0.5054 - 1.387 0.478 - 67.2 1 2 0 -0.0008 15 0 0 0 3.82E+06 2.06E+06 - - - 3.3755 0.9996 221125_WJC_METTL3_EV_vs_WT_F05.19721.19721.3 2.34E-08 Dec-88 R.APYPFAVENQNEAENTIQNEAQR[166.11].- sp|Q9HBI5|CC014_HUMAN 1 2642.2236 5.81 70533 19721 3 2643.227475 881.7485 Uncharacterized protein C3orf14 OS=Homo sapiens OX=9606 GN=C3orf14 PE=2 SV=1 4.09 3271.1 - 81884.5 - - - 379.9194 - 2.551 0.605 - 137.3 1 2 0 1.0038 23 0 0 0 4.04E+06 6.96E+05 - - - 7.204 1 221125_WJC_METTL3_EV_vs_WT_F05.19726.19726.3 3.26E-11 20/84 R.SSGAPAPGSGATIFALSSGQGR[166.11].C "sp|Q969Y2|GTPB3_HUMAN,tr|M0R0S9|M0R0S9_HUMAN,tr|M0R1X0|M0R1X0_HUMAN" 3 1984.9842 1.85 70536 19726 3 1984.988077 662.6687 "tRNA modification GTPase GTPBP3, mitochondrial OS=Homo sapiens OX=9606 GN=GTPBP3 PE=1 SV=2" 9.47 3271.8 - 623906 - - - 1.9592 - 3.215 0.585 - 386.3 1 2 0 0.0039 22 0 0 0 1.06E+07 5.73E+06 - - - 7.8298 1 221125_WJC_METTL3_EV_vs_WT_F05.19727.19727.3 3.19E-13 23/100 K.LIDDYGVEEEPAELPEGTSLTVDNKR.F sp|Q00577|PURA_HUMAN 1 2888.3927 2.14 70537 19727 3 2888.401519 963.8049 Transcriptional activator protein Pur-alpha OS=Homo sapiens OX=9606 GN=PURA PE=1 SV=2 3.89 3271.9 - 637306 - - - 3.0436 - 3.972 0.685 - 322.2 1 2 0 0.0088 26 0 0 0 1.44E+07 6.76E+06 - - - 9.3478 0.9997 221125_WJC_METTL3_EV_vs_WT_F05.19728.19728.3 8.68E-12 17/72 K.FVVDVDK[136.11]NIDINDVTPNC[160.03]R[166.11].V "sp|P62195|PRS8_HUMAN,tr|J3KRP2|J3KRP2_HUMAN,tr|J3QSA9|J3QSA9_HUMAN,tr|J3QLH6|J3QLH6_HUMAN,tr|J3QRW1|J3QRW1_HUMAN" 5 2250.107 0.92 70538 19728 3 2250.114563 751.0429 26S proteasome regulatory subunit 8 OS=Homo sapiens OX=9606 GN=PSMC5 PE=1 SV=1 4.14 3272.1 - 566364 - - - 3.3825 - 3.133 0.568 - 285.8 1 2 1 0.0076 19 0 0 0 4.48E+06 4.86E+06 - - - 7.6762 1 221125_WJC_METTL3_EV_vs_WT_F05.19731.19731.3 3.49E-15 23/84 K.R[166.11]VIISAPSADAPMFVMGVNHEK[136.11].Y "sp|P04406|G3P_HUMAN,tr|E7EUT5|E7EUT5_HUMAN" 2 2386.2256 1.08 70541 19731 3 2386.232119 796.4158 Glyceraldehyde-3-phosphate dehydrogenase OS=Homo sapiens OX=9606 GN=GAPDH PE=1 SV=3 6.75 3272.4 - 434612 - - - 2.7206 - 3.693 0.7 - 600.4 1 2 0 0.0065 22 0 0 0 5.83E+07 5.41E+07 - - - 9.4399 0.9945 221125_WJC_METTL3_EV_vs_WT_F05.19735.19735.2 2.23E-07 13/28 R.DISSSLNSLADSNAR[166.11].E sp|O94776|MTA2_HUMAN 1 1558.7462 2.9 70545 19735 2 1559.751462 780.3804 Metastasis-associated protein MTA2 OS=Homo sapiens OX=9606 GN=MTA2 PE=1 SV=1 4.21 3273 - 191518 - - - 644.8856 - 2.771 0.564 - 449.9 1 2 0 1.0052 15 0 0 0 1.86E+07 6.42E+06 - - - 5.3968 0.9999 221125_WJC_METTL3_EV_vs_WT_F05.19740.19740.4 0.000551 15/126 K.RVIISAPSADAPMFVMGVNHEK.Y "sp|P04406|G3P_HUMAN,tr|E7EUT5|E7EUT5_HUMAN" 2 2368.2032 1.2 70548 19740 4 2368.20486 593.0581 Glyceraldehyde-3-phosphate dehydrogenase OS=Homo sapiens OX=9606 GN=GAPDH PE=1 SV=3 6.75 3273.6 - 5.31E+06 - - - 0.7191 - 2.419 0.405 - 141.8 1 2 0 0.0017 22 0 0 0 1.57E+08 1.31E+08 - - - 3.0397 1 221125_WJC_METTL3_EV_vs_WT_F05.19742.19742.3 9.10E-12 29/100 K.LIDDYGVEEEPAELPEGTSLTVDNK[136.11]R[166.11].F sp|Q00577|PURA_HUMAN 1 2906.4152 2.14 70550 19742 3 2906.419273 969.8123 Transcriptional activator protein Pur-alpha OS=Homo sapiens OX=9606 GN=PURA PE=1 SV=2 3.89 3273.9 - 664746 - - - 1.4021 - 4.248 0.703 - 542.8 1 2 0 0.0041 26 0 0 0 1.44E+07 6.76E+06 - - - 9.7044 1 221125_WJC_METTL3_EV_vs_WT_F05.19745.19745.3 4.78E-12 22/80 K.FHDPDSAVVAQHLTNTVFVDR[166.11].A "sp|Q05519|SRS11_HUMAN,tr|Q5T760|Q5T760_HUMAN,tr|B4DWT1|B4DWT1_HUMAN" 3 2377.169 3.95 70553 19745 3 2377.161038 793.397 Serine\arginine-rich splicing factor 11 OS=Homo sapiens OX=9606 GN=SRSF11 PE=1 SV=1 5.13 3274.3 - 471635 - - - -3.3611 - 4.005 0.693 - 369 1 2 0 -0.008 21 0 0 0 2.02E+07 5.11E+06 - - - 9.5906 0.9997 221125_WJC_METTL3_EV_vs_WT_F05.19746.19746.3 4.58E-06 13/72 R.SSPLGQNDNSEYVPMLPGK.F "sp|O14654|IRS4_HUMAN,tr|A0A804CF45|A0A804CF45_HUMAN" 2 2031.9572 1.11 70554 19746 3 2031.965297 678.3263 Insulin receptor substrate 4 OS=Homo sapiens OX=9606 GN=IRS4 PE=1 SV=1 4.37 3274.4 - 392061 - - - 4.0065 - 2.302 0.511 - 133.5 1 2 0 0.0081 19 0 0 0 2.79E+07 2.52E+07 - - - 6.2833 0.9905 221125_WJC_METTL3_EV_vs_WT_F05.19749.19749.3 0.000245 Nov-56 R.DISSSLNSLADSNAR[166.11].E sp|O94776|MTA2_HUMAN 1 1558.7462 1.08 70557 19749 3 1559.748317 520.5894 Metastasis-associated protein MTA2 OS=Homo sapiens OX=9606 GN=MTA2 PE=1 SV=1 4.21 3274.8 - 266882 - - - 642.8679 - 1.899 0.373 - 111 1 2 0 1.0021 15 0 0 0 6.52E+06 6.03E+06 - - - 4.0945 0.9986 221125_WJC_METTL3_EV_vs_WT_F05.19750.19750.3 0.000298 Aug-60 K.IYGADDIELLPEAQHK.A "sp|P11586|C1TC_HUMAN,tr|F5H2F4|F5H2F4_HUMAN,tr|V9GZ78|V9GZ78_HUMAN,tr|V9GYY3|V9GYY3_HUMAN" 4 1810.9101 0.95 70558 19750 3 1810.914652 604.644 "C-1-tetrahydrofolate synthase, cytoplasmic OS=Homo sapiens OX=9606 GN=MTHFD1 PE=1 SV=4" 4.31 3274.9 - 251204 - - - 2.4976 - 1.859 0.327 - 61.9 1 2 0 0.0045 16 0 0 0 2.25E+06 2.38E+06 - - - 3.7754 0.9998 221125_WJC_METTL3_EV_vs_WT_F05.19751.19751.2 1.74E-07 Dec-36 R.SSPLGQNDNSEYVPMLPGK[136.11].F "sp|O14654|IRS4_HUMAN,tr|A0A804CF45|A0A804CF45_HUMAN" 2 2039.9714 1.39 70559 19751 2 2039.975198 1020.993 Insulin receptor substrate 4 OS=Homo sapiens OX=9606 GN=IRS4 PE=1 SV=1 4.37 3275 - 241638 - - - 1.8834 - 2.155 0.574 - 172.6 1 2 0 0.0038 19 0 0 0 1.85E+07 1.32E+07 - - - 5.167 0.9994 221125_WJC_METTL3_EV_vs_WT_F05.19752.19752.2 7.63E-05 Nov-36 R.SSPLGQNDNSEYVPMLPGK.F "sp|O14654|IRS4_HUMAN,tr|A0A804CF45|A0A804CF45_HUMAN" 2 2031.9572 1.39 70560 19752 2 2031.963719 1016.9859 Insulin receptor substrate 4 OS=Homo sapiens OX=9606 GN=IRS4 PE=1 SV=1 4.37 3275.2 - 210222 - - - 3.2299 - 2.114 0.55 - 172.9 1 2 0 0.0066 19 0 0 0 1.85E+07 1.32E+07 - - - 4.9417 1 221125_WJC_METTL3_EV_vs_WT_F05.19757.19757.4 1.94E-13 27/126 K.R[166.11]VIISAPSADAPMFVMGVNHEK[136.11].Y "sp|P04406|G3P_HUMAN,tr|E7EUT5|E7EUT5_HUMAN" 2 2386.2256 1.2 70563 19757 4 2386.225402 597.5637 Glyceraldehyde-3-phosphate dehydrogenase OS=Homo sapiens OX=9606 GN=GAPDH PE=1 SV=3 6.75 3275.9 - 1.18E+07 - - - -0.0943 - 4.127 0.681 - 458.3 1 2 0 -0.0002 22 0 0 0 1.57E+08 1.31E+08 - - - 5.6172 1 221125_WJC_METTL3_EV_vs_WT_F05.19758.19758.3 1.06E-10 25/84 K.RVIISAPSADAPMFVMGVNHEK.Y "sp|P04406|G3P_HUMAN,tr|E7EUT5|E7EUT5_HUMAN" 2 2368.2032 1.08 70564 19758 3 2368.200988 790.4083 Glyceraldehyde-3-phosphate dehydrogenase OS=Homo sapiens OX=9606 GN=GAPDH PE=1 SV=3 6.75 3275.9 - 3.80E+06 - - - -0.9159 - 3.996 0.687 - 598.9 1 2 0 -0.0022 22 0 0 0 5.83E+07 5.41E+07 - - - 9.4831 1 221125_WJC_METTL3_EV_vs_WT_F05.19759.19759.2 1.19E-09 15/28 R.DISSSLNSLADSNAR.E sp|O94776|MTA2_HUMAN 1 1548.738 2.9 70565 19759 2 1548.73821 775.3763 Metastasis-associated protein MTA2 OS=Homo sapiens OX=9606 GN=MTA2 PE=1 SV=1 4.21 3276.1 - 1.00E+06 - - - 0.1492 - 2.906 0.615 - 645.5 1 2 0 0.0002 15 0 0 0 1.86E+07 6.41E+06 - - - 6.206 0.9182 221125_WJC_METTL3_EV_vs_WT_F05.19770.19770.3 0.674 Sep-44 K.NK[136.11]YQELINDIAR[166.11].D "sp|P46940|IQGA1_HUMAN,tr|H0YLE8|H0YLE8_HUMAN" 2 1493.7957 0.58 70576 19770 3 1493.796642 498.9392 Ras GTPase-activating-like protein IQGAP1 OS=Homo sapiens OX=9606 GN=IQGAP1 PE=1 SV=1 6.07 3277.5 - 135980 - - - 0.6226 - 1.803 0.112 - 133.4 1 2 1 0.0009 12 0 0 0 1.24E+06 2.15E+06 - - - 1.4223 1 221125_WJC_METTL3_EV_vs_WT_F05.19773.19773.3 0.000127 16/72 R.SSPLGQNDNSEYVPMLPGK[136.11].F "sp|O14654|IRS4_HUMAN,tr|A0A804CF45|A0A804CF45_HUMAN" 2 2039.9714 1.11 70577 19773 3 2039.970571 680.9977 Insulin receptor substrate 4 OS=Homo sapiens OX=9606 GN=IRS4 PE=1 SV=1 4.37 3277.9 - 2.08E+06 - - - -0.3848 - 2.406 0.489 - 210.7 1 2 0 -0.0008 19 0 0 0 2.80E+07 2.52E+07 - - - 6.1486 1 221125_WJC_METTL3_EV_vs_WT_F05.19776.19776.3 1.40E-08 24/84 K.APSEEDSLSSVPISPYKDEPWK.Y "sp|Q9Y676|RT18B_HUMAN,tr|A0A0G2JIC6|A0A0G2JIC6_HUMAN" 2 2460.1697 1.07 70580 19776 3 2460.169602 821.0638 "28S ribosomal protein S18b, mitochondrial OS=Homo sapiens OX=9606 GN=MRPS18B PE=1 SV=1" 4.18 3278.3 - 973278 - - - -0.0199 - 4.071 0.657 - 633.8 1 2 1 -0.0001 22 0 0 0 2.67E+07 2.49E+07 - - - 9.1933 1 221125_WJC_METTL3_EV_vs_WT_F05.19779.19779.3 3.20E-12 20/80 K.ADR[166.11]DESSPYAAMLAAQDVAQR[166.11].C "sp|P62263|RS14_HUMAN,tr|A0A2R8Y811|A0A2R8Y811_HUMAN,tr|E5RH77|E5RH77_HUMAN" 3 2284.0657 1.36 70583 19779 3 2284.057994 762.3625 40S ribosomal protein S14 OS=Homo sapiens OX=9606 GN=RPS14 PE=1 SV=3 4.23 3278.7 - 710080 - - - -3.3734 - 4.106 0.72 - 560.9 1 2 1 -0.0077 21 0 0 0 1.20E+07 8.84E+06 - - - 9.9514 1 221125_WJC_METTL3_EV_vs_WT_F05.19780.19780.4 1.63E-08 28/120 R.ISLVLGGDHSLAIGSISGHAR.V "sp|P05089|ARGI1_HUMAN,tr|A0A5F9ZGN6|A0A5F9ZGN6_HUMAN" 2 2059.1174 31.09 70584 19780 4 2059.11627 515.7866 Arginase-1 OS=Homo sapiens OX=9606 GN=ARG1 PE=1 SV=2 6.92 3278.8 - 702234 - - - -0.5667 - 3.983 0.635 - 657.3 1 2 0 -0.0012 21 0 0 0 4.91E+07 1.58E+06 - - - 5.2097 1 221125_WJC_METTL3_EV_vs_WT_F05.19785.19785.3 6.32E-08 18/80 K.ADRDESSPYAAMLAAQDVAQR.C "sp|P62263|RS14_HUMAN,tr|A0A2R8Y811|A0A2R8Y811_HUMAN,tr|E5RH77|E5RH77_HUMAN" 3 2264.0492 1.36 70587 19785 3 2264.039618 755.6903 40S ribosomal protein S14 OS=Homo sapiens OX=9606 GN=RPS14 PE=1 SV=3 4.23 3279.4 - 704416 - - - -4.2141 - 3.96 0.629 - 490.3 1 2 1 -0.0095 21 0 0 0 1.20E+07 8.84E+06 - - - 8.8496 1 221125_WJC_METTL3_EV_vs_WT_F05.19786.19786.3 7.58E-05 22/80 R.ISLVLGGDHSLAIGSISGHAR.V "sp|P05089|ARGI1_HUMAN,tr|A0A5F9ZGN6|A0A5F9ZGN6_HUMAN" 2 2059.1174 44.31 70588 19786 3 2059.117936 687.3798 Arginase-1 OS=Homo sapiens OX=9606 GN=ARG1 PE=1 SV=2 6.92 3279.6 - 669485 - - - 0.2423 - 4.255 0.626 - 641 1 2 0 0.0005 21 0 0 0 1.29E+07 2.92E+05 - - - 8.9909 0.9999 221125_WJC_METTL3_EV_vs_WT_F05.19788.19788.3 1.41E-08 16/76 R.GTLSDEHAGVISVLAQQAAK[136.11].L "sp|O43504|LTOR5_HUMAN,tr|R4GMU8|R4GMU8_HUMAN,tr|A0A0C4DGV4|A0A0C4DGV4_HUMAN,tr|E9PLX3|E9PLX3_HUMAN" 4 2002.0575 0.7 70590 19788 3 2002.064922 668.3598 Ragulator complex protein LAMTOR5 OS=Homo sapiens OX=9606 GN=LAMTOR5 PE=1 SV=1 5.32 3279.8 - 491774 - - - 3.7227 - 3.214 0.575 - 284.9 1 2 0 0.0075 20 0 0 0 1.01E+07 1.44E+07 - - - 7.781 0.9974 221125_WJC_METTL3_EV_vs_WT_F05.19796.19796.3 5.13E-08 18/60 A.PSADAPMFVMGVNHEK[136.11].Y "sp|P04406|G3P_HUMAN,tr|E7EUT5|E7EUT5_HUMAN" 2 1736.8106 1.05 70596 19796 3 1736.8062 579.9441 Glyceraldehyde-3-phosphate dehydrogenase OS=Homo sapiens OX=9606 GN=GAPDH PE=1 SV=3 5.33 3281 - 227257 - - - -2.5115 - 3.098 0.628 - 310.3 1 1 0 -0.0044 16 0 0 0 3.48E+06 3.31E+06 - - - 8.4417 0.9961 221125_WJC_METTL3_EV_vs_WT_F05.19797.19797.4 1.34E-05 Oct-78 K.SHFELPHYPGLLAH.Q "sp|Q8TAX7|MUC7_HUMAN,tr|D6RHX1|D6RHX1_HUMAN" 2 1616.81 - 70597 19797 4 1616.810732 405.2098 Mucin-7 OS=Homo sapiens OX=9606 GN=MUC7 PE=1 SV=2 6.2 3281.1 - 206729 - - - 0.4762 - 2.244 0.512 - 89.9 1 1 0 0.0008 14 0 0 0 - - - - - 3.9764 1 221125_WJC_METTL3_EV_vs_WT_F05.19801.19801.3 3.40E-08 22/84 K.APSEEDSLSSVPISPYK[136.11]DEPWK[136.11].Y "sp|Q9Y676|RT18B_HUMAN,tr|A0A0G2JIC6|A0A0G2JIC6_HUMAN" 2 2476.1981 1.16 70599 19801 3 2476.197673 826.4066 "28S ribosomal protein S18b, mitochondrial OS=Homo sapiens OX=9606 GN=MRPS18B PE=1 SV=1" 4.18 3281.6 - 1.34E+06 - - - -0.1527 - 3.548 0.607 - 475.8 1 2 1 -0.0004 22 0 0 0 2.65E+07 2.28E+07 - - - 8.3097 1 221125_WJC_METTL3_EV_vs_WT_F05.19806.19806.2 3.39E-08 14/30 K.TITLEVEPSDTIENVK[136.11].A "sp|P62979|RS27A_HUMAN,sp|P0CG48|UBC_HUMAN,sp|P0CG47|UBB_HUMAN,sp|P62987|RL40_HUMAN,tr|F5H388|F5H388_HUMAN,tr|F5GYU3|F5GYU3_HUMAN,tr|B4DV12|B4DV12_HUMAN,tr|J3QSA3|J3QSA3_HUMAN,tr|Q5PY61|Q5PY61_HUMAN,tr|F5H2Z3|F5H2Z3_HUMAN,tr|J3QS39|J3QS39_HUMAN,tr|J3QTR3|J3QTR3_HUMAN,tr|Q96C32|Q96C32_HUMAN,tr|M0R1V7|M0R1V7_HUMAN,tr|F5H747|F5H747_HUMAN,tr|F5H747|F5H747_HUMAN,tr|F5GXK7|F5GXK7_HUMAN,tr|F5GXK7|F5GXK7_HUMAN,tr|F5H6Q2|F5H6Q2_HUMAN,tr|F5GZ39|F5GZ39_HUMAN,tr|J3QKN0|J3QKN0_HUMAN,tr|J3QKN0|J3QKN0_HUMAN,tr|J3QKN0|J3QKN0_HUMAN,tr|F5H265|F5H265_HUMAN" 24 1794.9342 0.64 70602 19806 2 1794.933834 898.4744 Ubiquitin-40S ribosomal protein S27a OS=Homo sapiens OX=9606 GN=RPS27A PE=1 SV=2 4 3282.3 - 711973 - - - -0.2178 - 2.8 0.619 - 527.8 1 2 0 -0.0004 16 0 0 0 8.62E+06 1.36E+07 - - - 6.1442 1 221125_WJC_METTL3_EV_vs_WT_F05.19810.19810.4 4.96E-12 31/156 K.EASPLPAESASAGATLRPLLLSGHGAR.E "sp|P35548|MSX2_HUMAN,tr|D6RIS4|D6RIS4_HUMAN" 2 2628.3984 2.2 70606 19810 4 2628.402724 658.1069 Homeobox protein MSX-2 OS=Homo sapiens OX=9606 GN=MSX2 PE=1 SV=3 6.86 3282.7 - 924459 - - - 1.6592 - 4.644 0.665 - 689.7 1 2 0 0.0044 27 0 0 0 1.39E+07 6.32E+06 - - - 5.4934 0.9876 221125_WJC_METTL3_EV_vs_WT_F05.19811.19811.3 3.90E-05 15/52 N.GDKEIGNIISDAMK.K "sp|P10809|CH60_HUMAN,tr|A0A7I2V599|A0A7I2V599_HUMAN,tr|E7EXB4|E7EXB4_HUMAN,tr|A0A7I2YQ71|A0A7I2YQ71_HUMAN,tr|E7ESH4|E7ESH4_HUMAN,tr|A0A7I2V5M1|A0A7I2V5M1_HUMAN,tr|A0A7I2V5K3|A0A7I2V5K3_HUMAN,tr|A0A7I2V369|A0A7I2V369_HUMAN" 8 1489.7446 1.36 70607 19811 3 1489.74449 497.5888 "60 kDa heat shock protein, mitochondrial OS=Homo sapiens OX=9606 GN=HSPD1 PE=1 SV=2" 4.56 3282.9 - 672589 - - - -0.1034 - 2.981 0.471 - 371.5 1 1 1 -0.0002 14 0 0 0 1.86E+07 1.37E+07 - - - 6.6939 1 221125_WJC_METTL3_EV_vs_WT_F05.19812.19812.3 6.79E-07 14/56 K.RAC[160.03]DESFQPLGDIMK.M "sp|Q6Y7W6|GGYF2_HUMAN,tr|A0A7I2V3H7|A0A7I2V3H7_HUMAN,tr|I1E4Y6|I1E4Y6_HUMAN,tr|A0A7I2V516|A0A7I2V516_HUMAN,tr|A0A7I2V3H0|A0A7I2V3H0_HUMAN,tr|C9JHW1|C9JHW1_HUMAN,tr|A0A7I2V361|A0A7I2V361_HUMAN,tr|E7ESB6|E7ESB6_HUMAN" 8 1765.8127 2.37 70608 19812 3 1765.814033 589.6115 GRB10-interacting GYF protein 2 OS=Homo sapiens OX=9606 GN=GIGYF2 PE=1 SV=1 4.56 3283 - 418130 - - - 0.7317 - 2.37 0.494 - 271.9 1 2 0 0.0013 15 0 0 0 8.74E+06 3.68E+06 - - - 6.2988 0.8324 221125_WJC_METTL3_EV_vs_WT_F05.19815.19815.3 0.00715 15/52 N.GDK[136.11]EIGNIISDAMK[136.11].K "sp|P10809|CH60_HUMAN,tr|A0A7I2V599|A0A7I2V599_HUMAN,tr|E7EXB4|E7EXB4_HUMAN,tr|A0A7I2YQ71|A0A7I2YQ71_HUMAN,tr|E7ESH4|E7ESH4_HUMAN,tr|A0A7I2V5M1|A0A7I2V5M1_HUMAN,tr|A0A7I2V5K3|A0A7I2V5K3_HUMAN,tr|A0A7I2V369|A0A7I2V369_HUMAN" 8 1505.773 1.36 70609 19815 3 1505.769566 502.9316 "60 kDa heat shock protein, mitochondrial OS=Homo sapiens OX=9606 GN=HSPD1 PE=1 SV=2" 4.56 3283.4 - 685856 - - - -2.3098 - 2.332 0.345 - 261.3 1 1 1 -0.0035 14 0 0 0 1.86E+07 1.37E+07 - - - 4.6356 1 221125_WJC_METTL3_EV_vs_WT_F05.19816.19816.2 0.000203 18/30 K.TITLEVEPSDTIENVK.A "sp|P62979|RS27A_HUMAN,sp|P0CG48|UBC_HUMAN,sp|P0CG47|UBB_HUMAN,sp|P62987|RL40_HUMAN,tr|F5H388|F5H388_HUMAN,tr|F5GYU3|F5GYU3_HUMAN,tr|B4DV12|B4DV12_HUMAN,tr|J3QSA3|J3QSA3_HUMAN,tr|Q5PY61|Q5PY61_HUMAN,tr|F5H2Z3|F5H2Z3_HUMAN,tr|J3QS39|J3QS39_HUMAN,tr|J3QTR3|J3QTR3_HUMAN,tr|Q96C32|Q96C32_HUMAN,tr|M0R1V7|M0R1V7_HUMAN,tr|F5H747|F5H747_HUMAN,tr|F5H747|F5H747_HUMAN,tr|F5GXK7|F5GXK7_HUMAN,tr|F5GXK7|F5GXK7_HUMAN,tr|F5H6Q2|F5H6Q2_HUMAN,tr|F5GZ39|F5GZ39_HUMAN,tr|J3QKN0|J3QKN0_HUMAN,tr|J3QKN0|J3QKN0_HUMAN,tr|J3QKN0|J3QKN0_HUMAN,tr|F5H265|F5H265_HUMAN" 24 1786.92 0.44 70610 19816 2 1786.916553 894.4673 Ubiquitin-40S ribosomal protein S27a OS=Homo sapiens OX=9606 GN=RPS27A PE=1 SV=2 4 3283.5 - 593469 - - - -1.943 - 3.593 0.619 - 944 1 2 0 -0.0035 16 0 0 0 9.20E+06 2.08E+07 - - - 6.7563 0.9999 221125_WJC_METTL3_EV_vs_WT_F05.19818.19818.3 3.60E-05 Dec-48 K.KGDILTLLNSTNK.D "sp|Q13813|SPTN1_HUMAN,tr|A0A0D9SF54|A0A0D9SF54_HUMAN,tr|A0A0D9SGF6|A0A0D9SGF6_HUMAN" 3 1415.7984 1.44 70612 19818 3 1415.801748 472.9401 "Spectrin alpha chain, non-erythrocytic 1 OS=Homo sapiens OX=9606 GN=SPTAN1 PE=1 SV=3" 8.59 3283.8 - 307675 - - - 2.369 - 2.54 0.491 - 360.6 1 2 0 0.0034 13 0 0 0 5.36E+06 3.73E+06 - - - 6.5406 0.9999 221125_WJC_METTL3_EV_vs_WT_F05.19824.19824.3 2.45E-05 18/68 K.ELQQELQEYEVVTESEKR.D sp|Q96A49|SYAP1_HUMAN 1 2236.0859 1.48 70616 19824 3 2236.085761 746.3693 Synapse-associated protein 1 OS=Homo sapiens OX=9606 GN=SYAP1 PE=1 SV=1 4.21 3284.5 - 620365 - - - -0.072 - 2.852 0.417 - 405.6 1 2 0 -0.0002 18 0 0 0 7.02E+06 4.73E+06 - - - 5.7988 1 221125_WJC_METTL3_EV_vs_WT_F05.19830.19830.2 1.56E-08 Dec-32 P.HDIIDDINSGAVEC[160.03]PAS.- sp|P30050|RL12_HUMAN 1 1811.7996 - 70621 19830 2 1811.794917 906.9071 60S ribosomal protein L12 OS=Homo sapiens OX=9606 GN=RPL12 PE=1 SV=1 3.84 3285.2 - 242176 - - - -2.5809 - 2.918 0.666 - 313.1 1 1 0 -0.0047 17 0 0 0 - - - - - 6.5915 1 221125_WJC_METTL3_EV_vs_WT_F05.19832.19832.3 1.98E-13 16/92 R.YYEDLDEVSSTSSVSQSLESEDAR[166.11].T "sp|P35658|NU214_HUMAN,tr|A0A0A0MSW3|A0A0A0MSW3_HUMAN,tr|A0A494C1F2|A0A494C1F2_HUMAN" 3 2705.1703 2.09 70622 19832 3 2705.168061 902.7307 Nuclear pore complex protein Nup214 OS=Homo sapiens OX=9606 GN=NUP214 PE=1 SV=2 3.66 3285.6 - 542912 - - - -0.8384 - 3.508 0.745 - 281.9 1 2 0 -0.0023 24 0 0 0 1.04E+07 4.95E+06 - - - 9.7604 0.9984 221125_WJC_METTL3_EV_vs_WT_F05.19833.19833.3 0.00202 Nov-60 K.TITLEVEPSDTIENVK[136.11].A "sp|P62979|RS27A_HUMAN,sp|P0CG48|UBC_HUMAN,sp|P0CG47|UBB_HUMAN,sp|P62987|RL40_HUMAN,tr|F5H388|F5H388_HUMAN,tr|F5GYU3|F5GYU3_HUMAN,tr|B4DV12|B4DV12_HUMAN,tr|J3QSA3|J3QSA3_HUMAN,tr|Q5PY61|Q5PY61_HUMAN,tr|F5H2Z3|F5H2Z3_HUMAN,tr|J3QS39|J3QS39_HUMAN,tr|J3QTR3|J3QTR3_HUMAN,tr|Q96C32|Q96C32_HUMAN,tr|M0R1V7|M0R1V7_HUMAN,tr|F5H747|F5H747_HUMAN,tr|F5H747|F5H747_HUMAN,tr|F5GXK7|F5GXK7_HUMAN,tr|F5GXK7|F5GXK7_HUMAN,tr|F5H6Q2|F5H6Q2_HUMAN,tr|F5GZ39|F5GZ39_HUMAN,tr|J3QKN0|J3QKN0_HUMAN,tr|J3QKN0|J3QKN0_HUMAN,tr|J3QKN0|J3QKN0_HUMAN,tr|F5H265|F5H265_HUMAN" 24 1794.9342 1.75 70623 19833 3 1794.940501 599.3187 Ubiquitin-40S ribosomal protein S27a OS=Homo sapiens OX=9606 GN=RPS27A PE=1 SV=2 4 3285.7 - 426212 - - - 3.4965 - 2.09 0.343 - 59.4 1 2 0 0.0063 16 0 0 0 3.38E+07 1.93E+07 - - - 4.2538 1 221125_WJC_METTL3_EV_vs_WT_F05.19834.19834.3 0.000213 13/48 K.K[136.11]GDILTLLNSTNK[136.11].D "sp|Q13813|SPTN1_HUMAN,tr|A0A0D9SF54|A0A0D9SF54_HUMAN,tr|A0A0D9SGF6|A0A0D9SGF6_HUMAN" 3 1431.8268 1.44 70624 19834 3 1431.825952 478.2829 "Spectrin alpha chain, non-erythrocytic 1 OS=Homo sapiens OX=9606 GN=SPTAN1 PE=1 SV=3" 8.59 3285.9 - 363433 - - - -0.5881 - 2.683 0.494 - 417.8 1 2 0 -0.0008 13 0 0 0 5.36E+06 3.73E+06 - - - 6.7232 0.9999 221125_WJC_METTL3_EV_vs_WT_F05.19835.19835.3 0.00034 Sep-72 R.GLLQDDAHPTLVTYADHSK[136.11].L "sp|Q86U44|MTA70_HUMAN,tr|F5H6D8|F5H6D8_HUMAN,tr|H0YFV6|H0YFV6_HUMAN,tr|B4DTN4|B4DTN4_HUMAN" 4 2088.0367 0.17 70625 19835 3 2088.036906 697.0195 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 5.13 3286 - 231358 - - - 0.0829 - 2.136 0.433 - 101.2 1 2 0 0.0002 19 0 0 0 8.21E+05 4.81E+06 - - - 5.232 0.998 221125_WJC_METTL3_EV_vs_WT_F05.19837.19837.3 0.000162 May-76 K.C[160.03]YLFGGLANDSEDPK[136.11]NNIPR[166.11].Y "sp|P51610|HCFC1_HUMAN,tr|A6NEM2|A6NEM2_HUMAN" 2 2297.0866 0.73 70627 19837 3 2297.079334 766.7028 Host cell factor 1 OS=Homo sapiens OX=9606 GN=HCFC1 PE=1 SV=2 4.56 3286.2 - 198923 - - - -3.1418 - 1.637 0.486 - 18.2 1 2 1 -0.0072 20 0 0 0 1.34E+06 1.85E+06 - - - 5.1521 0.9937 221125_WJC_METTL3_EV_vs_WT_F05.19838.19838.4 0.0201 7/138 K.FLNADVQGIHSENGPVLVEELGK[136.11]K[136.11].H "sp|Q01804|OTUD4_HUMAN,tr|D6RI06|D6RI06_HUMAN" 2 2608.3832 2.67 70628 19838 4 2608.382696 653.1031 OTU domain-containing protein 4 OS=Homo sapiens OX=9606 GN=OTUD4 PE=1 SV=4 4.83 3286.4 - 177237 - - - -0.1806 - 1.592 0.225 - 18.5 1 2 0 -0.0005 24 0 0 0 1.32E+07 4.96E+06 - - - 1.3335 0.9985 221125_WJC_METTL3_EV_vs_WT_F05.19840.19840.3 0.014 Oct-44 R.TRLGLEDFESLK.V sp|Q15208|STK38_HUMAN 1 1406.7405 2.09 70630 19840 3 1406.742168 469.9208 Serine\threonine-protein kinase 38 OS=Homo sapiens OX=9606 GN=STK38 PE=1 SV=1 4.68 3286.6 - 120011 - - - 1.1537 - 2.135 0.328 - 136.9 1 2 1 0.0016 12 0 0 0 1.45E+06 6.96E+05 - - - 4.2988 1 221125_WJC_METTL3_EV_vs_WT_F05.19844.19844.3 1.07E-08 25/68 K.DFDFESANAQFNKEEIDR.E "sp|Q8ND56|LS14A_HUMAN,tr|A0A140TA76|A0A140TA76_HUMAN,tr|K7EMZ9|K7EMZ9_HUMAN" 3 2173.9552 1.07 70633 19844 3 2173.956256 725.659 Protein LSM14 homolog A OS=Homo sapiens OX=9606 GN=LSM14A PE=1 SV=3 4.02 3287.1 - 973297 - - - 0.4664 - 4.251 0.703 - 590.1 1 2 1 0.001 18 0 0 0 8.88E+08 8.26E+08 - - - 9.981 1 221125_WJC_METTL3_EV_vs_WT_F05.19845.19845.3 9.56E-11 21/92 R.YYEDLDEVSSTSSVSQSLESEDAR.T "sp|P35658|NU214_HUMAN,tr|A0A0A0MSW3|A0A0A0MSW3_HUMAN,tr|A0A494C1F2|A0A494C1F2_HUMAN" 3 2695.1621 2.09 70634 19845 3 2695.165759 899.3946 Nuclear pore complex protein Nup214 OS=Homo sapiens OX=9606 GN=NUP214 PE=1 SV=2 3.66 3287.2 - 707169 - - - 1.3728 - 3.207 0.698 - 482.9 1 2 0 0.0037 24 0 0 0 1.04E+07 4.95E+06 - - - 9.0276 1 221125_WJC_METTL3_EV_vs_WT_F05.19846.19846.4 2.90E-07 15/138 K.FLNADVQGIHSENGPVLVEELGKK.H "sp|Q01804|OTUD4_HUMAN,tr|D6RI06|D6RI06_HUMAN" 2 2592.3548 2.68 70635 19846 4 2592.358288 649.096 OTU domain-containing protein 4 OS=Homo sapiens OX=9606 GN=OTUD4 PE=1 SV=4 4.83 3287.4 - 497012 - - - 1.3582 - 2.721 0.613 - 96.5 1 2 0 0.0035 24 0 0 0 1.33E+07 4.96E+06 - - - 4.8819 0.9993 221125_WJC_METTL3_EV_vs_WT_F05.19850.19850.3 1.43E-08 16/60 R.FRVDEEFQSPFASQSR.G "sp|P48645|NMU_HUMAN,tr|A0A0B4J202|A0A0B4J202_HUMAN,tr|D6RBC9|D6RBC9_HUMAN" 3 1928.9017 1.4 70639 19850 3 1928.910164 643.9745 Neuromedin-U OS=Homo sapiens OX=9606 GN=NMU PE=1 SV=1 4.68 3287.9 - 284474 - - - 4.3932 - 3.054 0.566 - 403 1 2 1 0.0085 16 0 0 0 1.13E+07 8.10E+06 - - - 7.7127 0.9693 221125_WJC_METTL3_EV_vs_WT_F05.19853.19853.3 0.000613 Oct-76 R.EIK[136.11]NELLQAQNPSELYLSSK[136.11].T sp|Q9UL15|BAG5_HUMAN 1 2319.2293 1.13 70642 19853 3 2320.236995 774.0837 BAG family molecular chaperone regulator 5 OS=Homo sapiens OX=9606 GN=BAG5 PE=1 SV=1 4.79 3288.3 - 107971 - - - 434.4991 - 2.214 0.425 - 99.5 1 2 1 1.0077 20 0 0 0 1.87E+06 1.66E+06 - - - 4.9274 1 221125_WJC_METTL3_EV_vs_WT_F05.19857.19857.3 1.26E-10 19/72 R.EDLMGLAIGTHGANIQQAR[166.11].K "sp|P51116|FXR2_HUMAN,sp|Q06787|FMR1_HUMAN,tr|A0A087WY29|A0A087WY29_HUMAN,tr|R9WNI0|R9WNI0_HUMAN,tr|A8MQB8|A8MQB8_HUMAN,tr|A0A087WWR6|A0A087WWR6_HUMAN,tr|A0A087WXI3|A0A087WXI3_HUMAN,tr|Q8IXW7|Q8IXW7_HUMAN,tr|G3V0J0|G3V0J0_HUMAN" 9 2004.0086 1.7 70644 19857 3 2004.007733 669.0102 Fragile X mental retardation syndrome-related protein 2 OS=Homo sapiens OX=9606 GN=FXR2 PE=1 SV=2 5.32 3288.8 - 976342 - - - -0.4466 - 4.041 0.659 - 565 1 2 0 -0.0009 19 0 0 0 1.27E+07 7.47E+06 - - - 9.3179 1 221125_WJC_METTL3_EV_vs_WT_F05.19858.19858.3 7.56E-05 21/100 R.GAYGGGYGGYDDYNGYNDGYGFGSDR[166.11].F "sp|P31943|HNRH1_HUMAN,tr|H0YBD7|H0YBD7_HUMAN,tr|H0YB39|H0YB39_HUMAN,tr|E9PCY7|E9PCY7_HUMAN,tr|G8JLB6|G8JLB6_HUMAN" 5 2726.0457 1.24 70645 19858 3 2726.047071 909.6892 Heterogeneous nuclear ribonucleoprotein H OS=Homo sapiens OX=9606 GN=HNRNPH1 PE=1 SV=4 3.77 3288.9 - 805671 - - - 0.489 - 3.332 0.699 - 358.4 1 2 0 0.0013 26 0 0 0 1.30E+07 1.05E+07 - - - 9.1018 1 221125_WJC_METTL3_EV_vs_WT_F05.19861.19861.2 1.94E-09 14/34 K.DFDFESANAQFNK[136.11]EEIDR[166.11].E "sp|Q8ND56|LS14A_HUMAN,tr|A0A140TA76|A0A140TA76_HUMAN,tr|K7EMZ9|K7EMZ9_HUMAN" 3 2191.9777 1.15 70648 19861 2 2191.976455 1096.9961 Protein LSM14 homolog A OS=Homo sapiens OX=9606 GN=LSM14A PE=1 SV=3 4.02 3289.3 - 96852.7 - - - -0.5735 - 3.206 0.702 - 522.1 1 2 1 -0.0013 18 0 0 0 1.67E+07 1.46E+07 - - - 7.0898 1 221125_WJC_METTL3_EV_vs_WT_F05.19866.19866.3 2.81E-06 15/100 R.GAYGGGYGGYDDYNGYNDGYGFGSDR.F "sp|P31943|HNRH1_HUMAN,tr|H0YBD7|H0YBD7_HUMAN,tr|H0YB39|H0YB39_HUMAN,tr|E9PCY7|E9PCY7_HUMAN,tr|G8JLB6|G8JLB6_HUMAN" 5 2716.0375 1.24 70651 19866 3 2716.038916 906.3531 Heterogeneous nuclear ribonucleoprotein H OS=Homo sapiens OX=9606 GN=HNRNPH1 PE=1 SV=4 3.77 3290 - 1.51E+06 - - - 0.5331 - 2.479 0.716 - 137.9 1 2 0 0.0014 26 0 0 0 1.30E+07 1.05E+07 - - - 8.6109 0.8254 221125_WJC_METTL3_EV_vs_WT_F05.19869.19869.3 0.00263 10/100 K.SLPGQNEDLVLTGYQVDKNKDDELTG.F sp|P01040|CYTA_HUMAN 1 2847.3774 4.25 70654 19869 3 2847.381329 950.1331 Cystatin-A OS=Homo sapiens OX=9606 GN=CSTA PE=1 SV=1 3.96 3290.4 - 389000 - - - 1.3757 - 2.01 0.36 - 51.9 1 1 2 0.0039 26 0 0 0 9.11E+06 2.14E+06 - - - 4.1587 1 221125_WJC_METTL3_EV_vs_WT_F05.19874.19874.2 3.31E-16 19/34 K.DFDFESANAQFNKEEIDR.E "sp|Q8ND56|LS14A_HUMAN,tr|A0A140TA76|A0A140TA76_HUMAN,tr|K7EMZ9|K7EMZ9_HUMAN" 3 2173.9552 1.15 70659 19874 2 2173.958849 1087.9849 Protein LSM14 homolog A OS=Homo sapiens OX=9606 GN=LSM14A PE=1 SV=3 4.02 3291 - 229739 - - - 1.6592 - 4.024 0.759 - 1100.3 1 2 1 0.0036 18 0 0 0 1.67E+07 1.46E+07 - - - 8.0688 0.9997 221125_WJC_METTL3_EV_vs_WT_F05.19876.19876.3 6.89E-05 Nov-60 K.KAEALEAAIENLNEAK.N "sp|Q9UJX4|APC5_HUMAN,tr|F5H0F9|F5H0F9_HUMAN,tr|F5H0N1|F5H0N1_HUMAN" 3 1712.8945 0.96 70661 19876 3 1712.901073 571.9721 Anaphase-promoting complex subunit 5 OS=Homo sapiens OX=9606 GN=ANAPC5 PE=1 SV=2 4.49 3291.3 - 189927 - - - 3.8496 - 2.446 0.469 - 105.1 1 2 0 0.0066 16 0 0 0 1.90E+06 1.99E+06 - - - 6.0621 0.9997 221125_WJC_METTL3_EV_vs_WT_F05.19883.19883.2 0.0132 14-Sep R.VDEIIWVK[136.11].T sp|Q86U44|MTA70_HUMAN 1 1008.5735 0.02 70666 19883 2 1008.57359 505.294 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 4.37 3292.2 - 1.34E+06 - - - 0.0565 - 2.086 0.326 - 284.2 1 2 0 0.0001 8 0 0 0 2.65E+06 1.69E+08 - - - 3.6663 1 221125_WJC_METTL3_EV_vs_WT_F05.19884.19884.3 2.06E-05 13/48 R.KTNNFSAFLANVR.K sp|Q9HBM1|SPC25_HUMAN 1 1480.7787 2.97 70667 19884 3 1480.777219 494.6002 Kinetochore protein Spc25 OS=Homo sapiens OX=9606 GN=SPC25 PE=1 SV=1 11 3292.3 - 835277 - - - -0.9745 - 2.344 0.474 - 183 1 2 0 -0.0014 13 0 0 0 1.35E+07 4.57E+06 - - - 6.1339 0.999 221125_WJC_METTL3_EV_vs_WT_F05.19887.19887.3 8.38E-08 15/48 R.K[136.11]TNNFSAFLANVR[166.11].K sp|Q9HBM1|SPC25_HUMAN 1 1498.8011 2.97 70670 19887 3 1499.806706 500.6077 Kinetochore protein Spc25 OS=Homo sapiens OX=9606 GN=SPC25 PE=1 SV=1 11 3292.7 - 371232 - - - 670.9189 - 2.661 0.527 - 233.4 1 2 0 1.0056 13 0 0 0 1.35E+07 4.57E+06 - - - 6.7905 1 221125_WJC_METTL3_EV_vs_WT_F05.19893.19893.3 7.26E-10 23/68 K.DFDFESANAQFNK[136.11]EEIDR[166.11].E "sp|Q8ND56|LS14A_HUMAN,tr|A0A140TA76|A0A140TA76_HUMAN,tr|K7EMZ9|K7EMZ9_HUMAN" 3 2191.9777 1.07 70675 19893 3 2191.974277 731.6665 Protein LSM14 homolog A OS=Homo sapiens OX=9606 GN=LSM14A PE=1 SV=3 4.02 3293.3 - 8.86E+07 - - - -1.5671 - 4.011 0.702 - 419.7 1 2 1 -0.0034 18 0 0 0 8.86E+08 8.25E+08 - - - 9.8245 0.999 221125_WJC_METTL3_EV_vs_WT_F05.19896.19896.4 0.00737 8/144 K.EVVAGAPR[166.11]PGLLSLAK[136.11]PLDAPAVNK[136.11].A "sp|O95785|WIZ_HUMAN,tr|A0A669KBG4|A0A669KBG4_HUMAN,tr|A0A2R8YFV2|A0A2R8YFV2_HUMAN,tr|A0A669KAV7|A0A669KAV7_HUMAN,tr|M0QXA7|M0QXA7_HUMAN,tr|A0A669KBH9|A0A669KBH9_HUMAN,tr|B9EGQ5|B9EGQ5_HUMAN" 7 2508.4638 1.95 70678 19896 4 2508.464243 628.1232 Protein Wiz OS=Homo sapiens OX=9606 GN=WIZ PE=1 SV=2 8.69 3293.7 - 352152 - - - 0.171 - 1.704 0.303 - 26.1 1 2 0 0.0004 25 0 0 0 3.70E+07 1.90E+07 - - - 2.0327 1 221125_WJC_METTL3_EV_vs_WT_F05.19903.19903.4 7.64E-05 14/144 K.EVVAGAPRPGLLSLAKPLDAPAVNK.A "sp|O95785|WIZ_HUMAN,tr|A0A669KBG4|A0A669KBG4_HUMAN,tr|A0A2R8YFV2|A0A2R8YFV2_HUMAN,tr|A0A669KAV7|A0A669KAV7_HUMAN,tr|M0QXA7|M0QXA7_HUMAN,tr|A0A669KBH9|A0A669KBH9_HUMAN,tr|B9EGQ5|B9EGQ5_HUMAN" 7 2482.4271 1.95 70683 19903 4 2482.428957 621.6141 Protein Wiz OS=Homo sapiens OX=9606 GN=WIZ PE=1 SV=2 8.69 3294.6 - 777147 - - - 0.7303 - 2.658 0.483 - 88.5 1 2 0 0.0018 25 0 0 0 3.70E+07 1.90E+07 - - - 3.7405 0.9999 221125_WJC_METTL3_EV_vs_WT_F05.19904.19904.2 1.17E-09 14/22 K.LNDLEEALQQAK.E sp|P35908|K22E_HUMAN 1 1370.7042 999 70684 19904 2 1370.703093 686.3594 "Keratin, type II cytoskeletal 2 epidermal OS=Homo sapiens OX=9606 GN=KRT2 PE=1 SV=2" 4.14 3294.7 - 588478 - - - -0.7777 - 3.023 0.498 - 774.7 1 2 0 -0.0011 12 0 0 0 9.01E+06 0.00E+00 - - - 5.6296 0.9969 221125_WJC_METTL3_EV_vs_WT_F05.19914.19914.3 5.79E-07 Nov-76 Y.TRPAISSFSSSGIGFGESLK.A sp|P49790|NU153_HUMAN 1 2027.0324 2.18 70692 19914 3 2027.035982 676.6847 Nuclear pore complex protein Nup153 OS=Homo sapiens OX=9606 GN=NUP153 PE=1 SV=2 8.41 3296 - 268887 - - - 1.7819 - 2.683 0.568 - 82.7 1 1 0 0.0036 20 0 0 0 2.31E+06 1.06E+06 - - - 7.266 0.9857 221125_WJC_METTL3_EV_vs_WT_F05.19917.19917.2 5.79E-05 22-Jun K.HTDESLGDC[160.03]SFL.N "sp|Q86U44|MTA70_HUMAN,tr|H0YFV6|H0YFV6_HUMAN" 2 1379.5663 - 70694 19917 2 1379.564125 690.7904 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 4.02 3296.4 - 170890 - - - -1.6092 - 1.432 0.617 - 52.9 1 1 0 -0.0022 12 0 0 0 - - - - - 4.5422 1 221125_WJC_METTL3_EV_vs_WT_F05.19922.19922.2 9.90E-12 16/32 R.TDASSASSFLDSDELER.T "sp|Q14498|RBM39_HUMAN,tr|A0A0U1RQW2|A0A0U1RQW2_HUMAN,tr|H0Y4X3|H0Y4X3_HUMAN,tr|A0A0U1RQH7|A0A0U1RQH7_HUMAN,tr|G3XAC6|G3XAC6_HUMAN" 5 1828.7963 1.45 70697 19922 2 1828.791782 915.4054 RNA-binding protein 39 OS=Homo sapiens OX=9606 GN=RBM39 PE=1 SV=2 3.77 3297 - 459340 - - - -2.4601 - 3.36 0.664 - 935.7 1 2 0 -0.0045 17 0 0 0 1.11E+07 7.69E+06 - - - 6.9235 0.9996 221125_WJC_METTL3_EV_vs_WT_F05.19923.19923.3 9.50E-05 15/56 K.GGNKQEEAWINPFVK.Q "sp|Q8NDV7|TNR6A_HUMAN,tr|H7C269|H7C269_HUMAN" 2 1715.8631 1.91 70698 19923 3 1715.863926 572.9616 Trinucleotide repeat-containing gene 6A protein OS=Homo sapiens OX=9606 GN=TNRC6A PE=1 SV=2 6.14 3297.1 - 401788 - - - 0.4697 - 2.088 0.435 - 272.1 1 2 1 0.0008 15 0 0 0 8.37E+06 4.38E+06 - - - 5.3106 1 221125_WJC_METTL3_EV_vs_WT_F05.19924.19924.2 0.000153 16/32 R.TDASSASSFLDSDELER[166.11].T "sp|Q14498|RBM39_HUMAN,tr|A0A0U1RQW2|A0A0U1RQW2_HUMAN,tr|H0Y4X3|H0Y4X3_HUMAN,tr|A0A0U1RQH7|A0A0U1RQH7_HUMAN,tr|G3XAC6|G3XAC6_HUMAN" 5 1838.8046 1.45 70699 19924 2 1838.808392 920.4096 RNA-binding protein 39 OS=Homo sapiens OX=9606 GN=RBM39 PE=1 SV=2 3.77 3297.3 - 348599 - - - 2.0889 - 3.406 0.671 - 869.8 1 2 0 0.0038 17 0 0 0 1.11E+07 7.69E+06 - - - 7.0088 0.9998 221125_WJC_METTL3_EV_vs_WT_F05.19928.19928.2 2.21E-08 Nov-32 R.SLGYAYVNFQQPADAER.A "sp|Q13310|PABP4_HUMAN,sp|P11940|PABP1_HUMAN,tr|A0A7I2V649|A0A7I2V649_HUMAN,tr|B1ANR0|B1ANR0_HUMAN,tr|A0A7I2V4L7|A0A7I2V4L7_HUMAN,tr|E5RHG7|E5RHG7_HUMAN,tr|B1ANR1|B1ANR1_HUMAN,tr|H0YAR2|H0YAR2_HUMAN,tr|E7ERJ7|E7ERJ7_HUMAN,tr|E5RJB9|E5RJB9_HUMAN,tr|A0A7I2YQ88|A0A7I2YQ88_HUMAN,tr|E5RH24|E5RH24_HUMAN,tr|H0YBN4|H0YBN4_HUMAN,tr|E5RGH3|E5RGH3_HUMAN,tr|A0A087WTT1|A0A087WTT1_HUMAN,tr|A0A7I2YQ90|A0A7I2YQ90_HUMAN,tr|E7EQV3|E7EQV3_HUMAN" 17 1927.9064 5.07 70703 19928 2 1927.902611 964.9605 Polyadenylate-binding protein 4 OS=Homo sapiens OX=9606 GN=PABPC4 PE=1 SV=1 4.37 3297.8 - 273950 - - - -1.9866 - 2.441 0.589 - 339.4 1 2 0 -0.0038 17 0 0 0 2.31E+06 4.56E+05 - - - 5.5842 0.9986 221125_WJC_METTL3_EV_vs_WT_F05.19938.19938.3 0.0318 Jul-44 R.KQVVNIPSFIVR.L sp|P46781|RS9_HUMAN 1 1398.8347 1.07 70711 19938 3 1398.83606 467.2855 40S ribosomal protein S9 OS=Homo sapiens OX=9606 GN=RPS9 PE=1 SV=3 11 3299 - 145728 - - - 0.9579 - 1.695 0.282 - 77.4 1 2 0 0.0013 12 0 0 0 1.71E+06 1.60E+06 - - - 3.1463 0.98 221125_WJC_METTL3_EV_vs_WT_F05.19951.19951.3 0.1 Jun-64 R.SLGYAYVNFQQPADAER.A "sp|Q13310|PABP4_HUMAN,sp|P11940|PABP1_HUMAN,tr|A0A7I2V649|A0A7I2V649_HUMAN,tr|B1ANR0|B1ANR0_HUMAN,tr|A0A7I2V4L7|A0A7I2V4L7_HUMAN,tr|E5RHG7|E5RHG7_HUMAN,tr|B1ANR1|B1ANR1_HUMAN,tr|H0YAR2|H0YAR2_HUMAN,tr|E7ERJ7|E7ERJ7_HUMAN,tr|E5RJB9|E5RJB9_HUMAN,tr|A0A7I2YQ88|A0A7I2YQ88_HUMAN,tr|E5RH24|E5RH24_HUMAN,tr|H0YBN4|H0YBN4_HUMAN,tr|E5RGH3|E5RGH3_HUMAN,tr|A0A087WTT1|A0A087WTT1_HUMAN,tr|A0A7I2YQ90|A0A7I2YQ90_HUMAN,tr|E7EQV3|E7EQV3_HUMAN" 17 1927.9064 10.64 70720 19951 3 1927.90339 643.6428 Polyadenylate-binding protein 4 OS=Homo sapiens OX=9606 GN=PABPC4 PE=1 SV=1 4.37 3300.8 - 183391 - - - -1.5825 - 1.178 0.235 - 38.7 1 2 0 -0.0031 17 0 0 0 7.65E+06 7.19E+05 - - - 1.573 1 221125_WJC_METTL3_EV_vs_WT_F05.19953.19953.4 3.01E-05 Nov-90 K.KEAAASGLPLMVIIHK.S sp|O95881|TXD12_HUMAN 1 1676.9647 1.17 70721 19953 4 1676.963247 420.2485 Thioredoxin domain-containing protein 12 OS=Homo sapiens OX=9606 GN=TXNDC12 PE=1 SV=1 8.6 3301 - 181666 - - - -0.8951 - 2.516 0.51 - 65.3 1 2 0 -0.0015 16 0 0 0 4.75E+06 4.05E+06 - - - 3.9896 0.9999 221125_WJC_METTL3_EV_vs_WT_F05.19963.19963.4 3.20E-11 19/120 R.KFGVVLDEIKPSSAPELQAVR.M "sp|O14579|COPE_HUMAN,tr|M0QXB4|M0QXB4_HUMAN,tr|M0R061|M0R061_HUMAN" 3 2282.2634 1.2 70728 19963 4 2282.258227 571.5731 Coatomer subunit epsilon OS=Homo sapiens OX=9606 GN=COPE PE=1 SV=3 6.18 3302.2 - 1.35E+06 - - - -2.2811 - 3.585 0.487 - 266.5 1 2 0 -0.0052 21 0 0 0 6.14E+07 5.13E+07 - - - 3.8856 1 221125_WJC_METTL3_EV_vs_WT_F05.19964.19964.3 1.10E-11 24/108 R.ALQAGQLENQAAPDDTQGSPDLGAVELR.L "sp|Q16512|PKN1_HUMAN,tr|K7EM57|K7EM57_HUMAN" 2 2863.3948 8.79 70729 19964 3 2863.3888 955.4722 Serine\threonine-protein kinase N1 OS=Homo sapiens OX=9606 GN=PKN1 PE=1 SV=2 3.77 3302.4 - 491276 - - - -2.0933 - 4.27 0.706 - 456.7 1 2 0 -0.006 28 0 0 0 2.67E+07 3.04E+06 - - - 9.7492 1 221125_WJC_METTL3_EV_vs_WT_F05.19970.19970.3 2.76E-07 19/60 R.LQQELDDLTVDLDHQR[166.11].Q sp|P35580|MYH10_HUMAN 1 1946.9573 1.33 70733 19970 3 1946.954115 649.993 Myosin-10 OS=Homo sapiens OX=9606 GN=MYH10 PE=1 SV=3 4.03 3303 - 452877 - - - -1.6379 - 3.42 0.538 - 676.6 1 2 0 -0.0032 16 0 0 0 3.47E+07 2.60E+07 - - - 7.6924 1 221125_WJC_METTL3_EV_vs_WT_F05.19973.19973.3 4.11E-07 15/60 R.LQQELDDLTVDLDHQR.Q sp|P35580|MYH10_HUMAN 1 1936.949 1.33 70735 19973 3 1936.943438 646.657 Myosin-10 OS=Homo sapiens OX=9606 GN=MYH10 PE=1 SV=3 4.03 3303.4 - 450549 - - - -2.8891 - 3.187 0.554 - 424.8 1 2 0 -0.0056 16 0 0 0 3.47E+07 2.60E+07 - - - 7.689 0.9975 221125_WJC_METTL3_EV_vs_WT_F05.19974.19974.4 0.027 Aug-90 R.IKDEFQFLQAQYHSLK.V "sp|Q04726|TLE3_HUMAN,tr|A0A0D9SES8|A0A0D9SES8_HUMAN,tr|H0YL70|H0YL70_HUMAN,tr|H0YKN8|H0YKN8_HUMAN,tr|H0YKT5|H0YKT5_HUMAN,tr|H0YLW9|H0YLW9_HUMAN,tr|H0YLI3|H0YLI3_HUMAN,tr|H0YKH0|H0YKH0_HUMAN" 8 1994.0262 1.24 70736 19974 4 1994.022349 499.5138 Transducin-like enhancer protein 3 OS=Homo sapiens OX=9606 GN=TLE3 PE=1 SV=2 6.75 3303.5 - 325958 - - - -1.9122 - 1.753 0.343 - 59.2 1 2 1 -0.0038 16 0 0 0 5.03E+06 4.07E+06 - - - 2.4081 1 221125_WJC_METTL3_EV_vs_WT_F05.19991.19991.2 2.80E-13 16/38 K.GNDISSGTVLSDYVGSGPPK.G sp|P30086|PEBP1_HUMAN 1 1948.9378 2.92 70743 19991 2 1948.933057 975.4762 Phosphatidylethanolamine-binding protein 1 OS=Homo sapiens OX=9606 GN=PEBP1 PE=1 SV=3 4.21 3305.8 - 417692 - - - -2.4341 - 3.501 0.725 - 573.9 1 2 0 -0.0047 20 0 0 0 2.95E+07 1.01E+07 - - - 7.475 1 221125_WJC_METTL3_EV_vs_WT_F05.19996.19996.2 7.30E-15 17/38 K.GNDISSGTVLSDYVGSGPPK[136.11].G sp|P30086|PEBP1_HUMAN 1 1956.952 2.92 70745 19996 2 1956.950318 979.4833 Phosphatidylethanolamine-binding protein 1 OS=Homo sapiens OX=9606 GN=PEBP1 PE=1 SV=3 4.21 3306.4 - 459192 - - - -0.86 - 3.357 0.752 - 785.6 1 2 0 -0.0017 20 0 0 0 2.95E+07 1.01E+07 - - - 7.5722 1 221125_WJC_METTL3_EV_vs_WT_F05.20006.20006.3 7.80E-13 17/72 K.QNLYDLDEDDDGIASVPTK.Q "sp|Q9BY77|PDIP3_HUMAN,tr|F6VRR5|F6VRR5_HUMAN,tr|F8WCX5|F8WCX5_HUMAN,tr|Q8WUT1|Q8WUT1_HUMAN,tr|F8WEE2|F8WEE2_HUMAN" 5 2106.9593 2.98 70750 20006 3 2106.957262 703.3271 Polymerase delta-interacting protein 3 OS=Homo sapiens OX=9606 GN=POLDIP3 PE=1 SV=2 3.61 3307.6 - 1.03E+06 - - - -0.9787 - 3.844 0.67 - 265.5 1 2 0 -0.0021 19 0 0 0 4.09E+07 1.37E+07 - - - 9.3174 1 221125_WJC_METTL3_EV_vs_WT_F05.20009.20009.2 4.68E-11 Nov-36 K.QNLYDLDEDDDGIASVPTK.Q "sp|Q9BY77|PDIP3_HUMAN,tr|F6VRR5|F6VRR5_HUMAN,tr|F8WCX5|F8WCX5_HUMAN,tr|Q8WUT1|Q8WUT1_HUMAN,tr|F8WEE2|F8WEE2_HUMAN" 5 2106.9593 2.03 70752 20009 2 2106.956938 1054.4869 Polymerase delta-interacting protein 3 OS=Homo sapiens OX=9606 GN=POLDIP3 PE=1 SV=2 3.61 3308 - 806335 - - - -1.1324 - 2.83 0.66 - 189.9 1 2 0 -0.0024 19 0 0 0 3.14E+07 1.55E+07 - - - 6.4726 0.9994 221125_WJC_METTL3_EV_vs_WT_F05.20013.20013.2 1.50E-07 22-Dec R.GYISPYFINTSK[136.11].G "sp|P10809|CH60_HUMAN,tr|A0A7I2V2X6|A0A7I2V2X6_HUMAN,tr|A0A7I2V599|A0A7I2V599_HUMAN,tr|A0A7I2YQ71|A0A7I2YQ71_HUMAN,tr|E7ESH4|E7ESH4_HUMAN,tr|A0A7I2V5M1|A0A7I2V5M1_HUMAN,tr|A0A7I2V5K3|A0A7I2V5K3_HUMAN,tr|A0A7I2V369|A0A7I2V369_HUMAN" 8 1396.7118 1.37 70754 20013 2 1396.706774 699.3632 "60 kDa heat shock protein, mitochondrial OS=Homo sapiens OX=9606 GN=HSPD1 PE=1 SV=2" 8.5 3308.5 - 691284 - - - -3.6106 - 2.504 0.577 - 578.6 1 2 0 -0.005 12 0 0 0 2.94E+07 2.14E+07 - - - 5.7163 1 221125_WJC_METTL3_EV_vs_WT_F05.20014.20014.4 2.88E-05 22/138 K.K[136.11]VTSVVFHPSQDLVFSASPDATIR[166.11].L sp|Q9UMS4|PRP19_HUMAN 1 2618.3823 1.2 70755 20014 4 2618.378091 655.6029 Pre-mRNA-processing factor 19 OS=Homo sapiens OX=9606 GN=PRPF19 PE=1 SV=1 6.75 3308.6 - 1.14E+06 - - - -1.6159 - 3.71 0.503 - 357.1 1 2 0 -0.0042 24 0 0 0 2.53E+07 2.11E+07 - - - 4.0237 0.9998 221125_WJC_METTL3_EV_vs_WT_F05.20015.20015.3 0.000843 Aug-68 K.DGDSVMVLPTIPEEEAK[136.11]K[136.11].L sp|P30041|PRDX6_HUMAN 1 1972.9998 1.07 70756 20015 3 1972.995015 658.6739 Peroxiredoxin-6 OS=Homo sapiens OX=9606 GN=PRDX6 PE=1 SV=3 4.18 3308.8 - 457964 - - - -2.4298 - 2.131 0.436 - 65 1 2 0 -0.0048 18 0 0 0 1.16E+07 1.09E+07 - - - 5.2836 0.999 221125_WJC_METTL3_EV_vs_WT_F05.20018.20018.2 3.53E-08 13/26 K.GGSTTGSQFLEQFK[136.11].T "sp|Q14157|UBP2L_HUMAN,tr|F8W726|F8W726_HUMAN" 2 1493.7242 2.17 70757 20018 2 1493.71779 747.8694 Ubiquitin-associated protein 2-like OS=Homo sapiens OX=9606 GN=UBAP2L PE=1 SV=2 6 3309.2 - 1.76E+06 - - - -4.2732 - 2.601 0.561 - 676.6 1 2 0 -0.0064 14 0 0 0 9.51E+07 4.39E+07 - - - 5.5813 0.9998 221125_WJC_METTL3_EV_vs_WT_F05.20019.20019.2 2.16E-05 13/22 R.GYISPYFINTSK.G "sp|P10809|CH60_HUMAN,tr|A0A7I2V2X6|A0A7I2V2X6_HUMAN,tr|A0A7I2V599|A0A7I2V599_HUMAN,tr|A0A7I2YQ71|A0A7I2YQ71_HUMAN,tr|E7ESH4|E7ESH4_HUMAN,tr|A0A7I2V5M1|A0A7I2V5M1_HUMAN,tr|A0A7I2V5K3|A0A7I2V5K3_HUMAN,tr|A0A7I2V369|A0A7I2V369_HUMAN" 8 1388.6976 1.35 70758 20019 2 1388.699301 695.3561 "60 kDa heat shock protein, mitochondrial OS=Homo sapiens OX=9606 GN=HSPD1 PE=1 SV=2" 8.5 3309.3 - 1.06E+06 - - - 1.2126 - 2.584 0.48 - 653.7 1 2 0 0.0017 12 0 0 0 2.89E+07 2.14E+07 - - - 5.0836 0.9998 221125_WJC_METTL3_EV_vs_WT_F05.20020.20020.4 1.86E-07 20/120 R.K[136.11]FGVVLDEIK[136.11]PSSAPELQAVR[166.11].M "sp|O14579|COPE_HUMAN,tr|M0QXB4|M0QXB4_HUMAN,tr|M0R061|M0R061_HUMAN" 3 2308.3001 1.19 70759 20020 4 2308.290558 578.0823 Coatomer subunit epsilon OS=Homo sapiens OX=9606 GN=COPE PE=1 SV=3 6.18 3309.4 - 1.20E+06 - - - -4.1351 - 3.845 0.491 - 342.5 1 2 0 -0.0095 21 0 0 0 6.12E+07 5.13E+07 - - - 3.9423 1 221125_WJC_METTL3_EV_vs_WT_F05.20028.20028.3 1.34E-08 16/72 K.QNLYDLDEDDDGIASVPTK[136.11].Q "sp|Q9BY77|PDIP3_HUMAN,tr|F6VRR5|F6VRR5_HUMAN,tr|F8WCX5|F8WCX5_HUMAN,tr|Q8WUT1|Q8WUT1_HUMAN,tr|F8WEE2|F8WEE2_HUMAN" 5 2114.9735 2.91 70764 20028 3 2114.979133 705.9985 Polymerase delta-interacting protein 3 OS=Homo sapiens OX=9606 GN=POLDIP3 PE=1 SV=2 3.61 3310.4 - 916397 - - - 2.652 - 3.097 0.64 - 238.6 1 2 0 0.0056 19 0 0 0 3.97E+07 1.37E+07 - - - 8.4511 1 221125_WJC_METTL3_EV_vs_WT_F05.20031.20031.3 7.76E-11 23/100 R.KYGGPPPDSVYSGVQPGIGTEVFVGK.L "sp|O43390|HNRPR_HUMAN,tr|A0A6Q8PEX7|A0A6Q8PEX7_HUMAN" 2 2634.333 1.85 70765 20031 3 2634.328596 879.1183 Heterogeneous nuclear ribonucleoprotein R OS=Homo sapiens OX=9606 GN=HNRNPR PE=1 SV=1 6.07 3310.7 - 873568 - - - -1.66 - 3.547 0.592 - 340.6 1 2 0 -0.0044 26 0 0 0 3.74E+07 2.02E+07 - - - 8.0518 1 221125_WJC_METTL3_EV_vs_WT_F05.20032.20032.2 1.12E-10 18/36 K.QNLYDLDEDDDGIASVPTK[136.11].Q "sp|Q9BY77|PDIP3_HUMAN,tr|F6VRR5|F6VRR5_HUMAN,tr|F8WCX5|F8WCX5_HUMAN,tr|Q8WUT1|Q8WUT1_HUMAN,tr|F8WEE2|F8WEE2_HUMAN" 5 2114.9735 2.03 70766 20032 2 2114.965641 1058.494 Polymerase delta-interacting protein 3 OS=Homo sapiens OX=9606 GN=POLDIP3 PE=1 SV=2 3.61 3310.9 - 649344 - - - -3.7272 - 3.584 0.748 - 657.2 1 2 0 -0.0079 19 0 0 0 3.14E+07 1.55E+07 - - - 7.7015 1 221125_WJC_METTL3_EV_vs_WT_F05.20033.20033.3 1.21E-09 23/52 K.R[166.11]PSENLGQVLFGER[166.11].L sp|Q99805|TM9S2_HUMAN 1 1620.8487 1.22 70767 20033 3 1620.847926 541.2902 Transmembrane 9 superfamily member 2 OS=Homo sapiens OX=9606 GN=TM9SF2 PE=1 SV=1 6.14 3311 - 1.03E+06 - - - -0.4738 - 4.216 0.533 - 1148.4 1 2 0 -0.0008 14 0 0 0 2.49E+07 2.05E+07 - - - 8.3061 1 221125_WJC_METTL3_EV_vs_WT_F05.20039.20039.3 1.07E-13 19/100 R.K[136.11]YGGPPPDSVYSGVQPGIGTEVFVGK[136.11].L "sp|O43390|HNRPR_HUMAN,tr|A0A6Q8PEX7|A0A6Q8PEX7_HUMAN" 2 2650.3614 1.85 70771 20039 3 2650.359108 884.4611 Heterogeneous nuclear ribonucleoprotein R OS=Homo sapiens OX=9606 GN=HNRNPR PE=1 SV=1 6.07 3311.8 - 722429 - - - -0.8531 - 3.762 0.688 - 250.5 1 2 0 -0.0023 26 0 0 0 3.74E+07 2.02E+07 - - - 9.2581 0.9993 221125_WJC_METTL3_EV_vs_WT_F05.20041.20041.3 0.00136 Oct-52 K.GGSTTGSQFLEQFK.T "sp|Q14157|UBP2L_HUMAN,tr|F8W726|F8W726_HUMAN" 2 1485.71 4.25 70773 20041 3 1485.705016 496.2439 Ubiquitin-associated protein 2-like OS=Homo sapiens OX=9606 GN=UBAP2L PE=1 SV=2 6 3312 - 539109 - - - -3.3365 - 2.024 0.397 - 99.1 1 2 0 -0.005 14 0 0 0 8.71E+06 2.05E+06 - - - 4.8385 1 221125_WJC_METTL3_EV_vs_WT_F05.20045.20045.2 1.80E-08 26-Dec K.GGSTTGSQFLEQFK.T "sp|Q14157|UBP2L_HUMAN,tr|F8W726|F8W726_HUMAN" 2 1485.71 2.17 70775 20045 2 1485.706302 743.8623 Ubiquitin-associated protein 2-like OS=Homo sapiens OX=9606 GN=UBAP2L PE=1 SV=2 6 3312.6 - 4.33E+06 - - - -2.4709 - 2.738 0.595 - 610.4 1 2 0 -0.0037 14 0 0 0 9.51E+07 4.39E+07 - - - 5.9621 0.8895 221125_WJC_METTL3_EV_vs_WT_F05.20049.20049.3 0.0754 Oct-56 R.VK[136.11]EDENVPFLLVGNK[136.11].S "sp|P11233|RALA_HUMAN,tr|H7C3P7|H7C3P7_HUMAN" 2 1715.9429 0.25 70779 20049 3 1715.951509 572.9882 Ras-related protein Ral-A OS=Homo sapiens OX=9606 GN=RALA PE=1 SV=1 4.68 3313.1 - 679656 - - - 5.0252 - 2.03 0.233 - 87.5 1 2 1 0.0086 15 0 0 0 5.94E+06 2.38E+07 - - - 2.9829 0.9999 221125_WJC_METTL3_EV_vs_WT_F05.20050.20050.4 1.73E-07 20/84 R.EVPIPEHIDIYHLTR[166.11].E "sp|Q9UG63|ABCF2_HUMAN,tr|C9JZV3|C9JZV3_HUMAN,tr|C9JHK9|C9JHK9_HUMAN" 3 1840.9711 0.57 70780 20050 4 1840.967176 461.2501 ATP-binding cassette sub-family F member 2 OS=Homo sapiens OX=9606 GN=ABCF2 PE=1 SV=2 5.28 3313.2 - 299508 - - - -2.1337 - 3.005 0.443 - 289.3 1 2 0 -0.0039 15 0 0 0 3.32E+06 5.82E+06 - - - 3.4745 0.9974 221125_WJC_METTL3_EV_vs_WT_F05.20054.20054.3 3.17E-06 15/64 M.QTQISETNVILSMDNNR.S sp|P04264|K2C1_HUMAN 1 1961.9477 5.74 70782 20054 3 1961.947996 654.9898 "Keratin, type II cytoskeletal 1 OS=Homo sapiens OX=9606 GN=KRT1 PE=1 SV=6" 4.37 3313.7 - 933476 - - - 0.1743 - 2.592 0.519 - 304.6 1 1 0 0.0003 17 0 0 0 2.69E+07 4.69E+06 - - - 6.7324 0.9988 221125_WJC_METTL3_EV_vs_WT_F05.20055.20055.4 0.000349 19/90 K.APIR[166.11]PDIVNFVHTNLR[166.11].K "sp|P36578|RL4_HUMAN,tr|H3BTP7|H3BTP7_HUMAN,tr|H3BU31|H3BU31_HUMAN" 3 1881.0488 1.2 70783 20055 4 1881.046663 471.2695 60S ribosomal protein L4 OS=Homo sapiens OX=9606 GN=RPL4 PE=1 SV=5 9.65 3313.8 - 757965 - - - -1.1313 - 2.625 0.278 - 234.8 1 2 0 -0.0021 16 0 0 0 1.50E+07 1.25E+07 - - - 1.9851 1 221125_WJC_METTL3_EV_vs_WT_F05.20056.20056.4 8.86E-07 13/132 K.SLLENDQLLSHGGQDLSADAFHR[166.11].L sp|Q9UBB9|TFP11_HUMAN 1 2532.2232 0.75 70784 20056 4 2532.223258 634.0631 Tuftelin-interacting protein 11 OS=Homo sapiens OX=9606 GN=TFIP11 PE=1 SV=1 4.63 3314 - 689732 - - - 0.0036 - 2.695 0.557 - 104.6 1 2 0 0 23 0 0 0 2.67E+06 3.55E+06 - - - 4.3953 0.9998 221125_WJC_METTL3_EV_vs_WT_F05.20057.20057.4 0.00647 20/90 K.APIRPDIVNFVHTNLR.K "sp|P36578|RL4_HUMAN,tr|H3BTP7|H3BTP7_HUMAN,tr|H3BU31|H3BU31_HUMAN" 3 1861.0323 1.17 70785 20057 4 1861.03097 466.2653 60S ribosomal protein L4 OS=Homo sapiens OX=9606 GN=RPL4 PE=1 SV=5 9.65 3314.1 - 642535 - - - -0.6883 - 2.75 0.372 - 270.7 1 2 0 -0.0013 16 0 0 0 1.49E+07 1.28E+07 - - - 2.8199 0.973 221125_WJC_METTL3_EV_vs_WT_F05.20061.20061.3 0.0177 Aug-64 K.KFYPLEIDYGQDEEAVK.K sp|P09874|PARP1_HUMAN 1 2042.9837 2.6 70789 20061 3 2042.993072 682.0018 Poly [ADP-ribose] polymerase 1 OS=Homo sapiens OX=9606 GN=PARP1 PE=1 SV=4 4.18 3314.6 - 327046 - - - 4.5933 - 1.877 0.248 - 62.2 2 2 0 0.0094 17 0 0 0 7.33E+06 2.82E+06 - - - 2.7538 1 221125_WJC_METTL3_EV_vs_WT_F05.20068.20068.2 1.10E-10 17/32 M.QTQISETNVILSMDNNR.S sp|P04264|K2C1_HUMAN 1 1961.9477 6.07 70794 20068 2 1961.94736 981.9811 "Keratin, type II cytoskeletal 1 OS=Homo sapiens OX=9606 GN=KRT1 PE=1 SV=6" 4.37 3315.4 - 897254 - - - -0.1499 - 3.48 0.698 - 1081.8 1 1 0 -0.0003 17 0 0 0 1.73E+07 2.85E+06 - - - 7.2622 1 221125_WJC_METTL3_EV_vs_WT_F05.20070.20070.3 6.40E-08 21/96 R.C[160.03]VLLSNLSSTSHVPEVDPGSAELQK[136.11].V "sp|P49327|FAS_HUMAN,tr|A0A0U1RQF0|A0A0U1RQF0_HUMAN" 2 2674.3363 0.66 70796 20070 3 2674.334201 892.4527 Fatty acid synthase OS=Homo sapiens OX=9606 GN=FASN PE=1 SV=3 4.65 3315.6 - 532257 - - - -0.8021 - 3.314 0.531 - 236.3 1 2 0 -0.0021 25 0 0 0 1.35E+07 2.04E+07 - - - 7.2161 0.9866 221125_WJC_METTL3_EV_vs_WT_F05.20071.20071.3 0.0342 13/64 R.GK[136.11]YSEVFEAINITNNEK[136.11].V "sp|P68400|CSK21_HUMAN,sp|Q8NEV1|CSK23_HUMAN,tr|A0A2R8YCK2|A0A2R8YCK2_HUMAN,tr|A0A2R8YFU2|A0A2R8YFU2_HUMAN,tr|V9GYA2|V9GYA2_HUMAN,tr|A0A2R8YEW1|A0A2R8YEW1_HUMAN,tr|A0A2R8Y4D6|A0A2R8Y4D6_HUMAN,tr|A0A2R8YD58|A0A2R8YD58_HUMAN,tr|A0A2R8YF43|A0A2R8YF43_HUMAN,tr|A0A2R8Y5A0|A0A2R8Y5A0_HUMAN,tr|A0A2R8YDY7|A0A2R8YDY7_HUMAN,tr|A0A2R8YF47|A0A2R8YF47_HUMAN,tr|A0A2R8Y4H0|A0A2R8Y4H0_HUMAN,tr|A0A2R8Y7T1|A0A2R8Y7T1_HUMAN,tr|A0A2R8YDP2|A0A2R8YDP2_HUMAN,tr|A0A2R8Y797|A0A2R8Y797_HUMAN,tr|A0A2R8YEL7|A0A2R8YEL7_HUMAN,tr|V9GY80|V9GY80_HUMAN,tr|E7EU96|E7EU96_HUMAN,tr|A0A2R8Y3W6|A0A2R8Y3W6_HUMAN" 20 1970.992 1.2 70797 20071 3 1970.989717 658.0046 Casein kinase II subunit alpha OS=Homo sapiens OX=9606 GN=CSNK2A1 PE=1 SV=1 4.79 3315.8 - 392834 - - - -1.1695 - 1.724 0.243 - 188.6 1 2 1 -0.0023 17 0 0 0 1.56E+07 1.31E+07 - - - 2.6245 0.8944 221125_WJC_METTL3_EV_vs_WT_F05.20072.20072.3 0.0637 Aug-60 R.K[136.11]YTTR[166.11]C[160.03]SYC[160.03]GEEGHSK[136.11].E sp|P0CG32|ZCC18_HUMAN 1 1987.8727 0.001 70798 20072 3 1987.868058 663.6315 Zinc finger CCHC domain-containing protein 18 OS=Homo sapiens OX=9606 GN=ZCCHC18 PE=3 SV=1 8.03 3315.9 - 294558 - - - -2.3181 - 1.606 0.178 - 61.5 1 2 1 -0.0046 16 0 0 0 0.00E+00 2.42E+06 - - - 1.7388 0.9999 221125_WJC_METTL3_EV_vs_WT_F05.20073.20073.3 0.00264 Nov-56 R.EVPIPEHIDIYHLTR[166.11].E "sp|Q9UG63|ABCF2_HUMAN,tr|C9JZV3|C9JZV3_HUMAN,tr|C9JHK9|C9JHK9_HUMAN" 3 1840.9711 2.9 70799 20073 3 1840.969618 614.6643 ATP-binding cassette sub-family F member 2 OS=Homo sapiens OX=9606 GN=ABCF2 PE=1 SV=2 5.28 3316 - 211709 - - - -0.8072 - 2.105 0.457 - 151.4 1 2 0 -0.0015 15 0 0 0 2.02E+06 6.98E+05 - - - 5.5769 0.9995 221125_WJC_METTL3_EV_vs_WT_F05.20075.20075.3 1.48E-05 Nov-64 K.QGGLGPMNIPLVSDPK[136.11]R[166.11].T "sp|Q06830|PRDX1_HUMAN,tr|A0A0A0MSI0|A0A0A0MSI0_HUMAN" 2 1795.9734 0.25 70800 20075 3 1795.967679 599.6651 Peroxiredoxin-1 OS=Homo sapiens OX=9606 GN=PRDX1 PE=1 SV=1 8.75 3316.4 - 417581 - - - -3.1626 - 2.038 0.416 - 110.1 1 2 0 -0.0057 17 0 0 0 4.47E+06 1.79E+07 - - - 4.9751 0.9999 221125_WJC_METTL3_EV_vs_WT_F05.20077.20077.2 0.000107 24-Sep K.DFDFESANAQFNK.E "sp|Q8ND56|LS14A_HUMAN,tr|A0A140TA76|A0A140TA76_HUMAN,tr|K7EMZ9|K7EMZ9_HUMAN" 3 1531.6579 2.88 70801 20077 2 1531.655818 766.8362 Protein LSM14 homolog A OS=Homo sapiens OX=9606 GN=LSM14A PE=1 SV=3 4.03 3316.6 - 522592 - - - -1.3835 - 2.214 0.607 - 186.5 1 2 0 -0.0021 13 0 0 0 5.11E+06 1.77E+06 - - - 5.5635 0.9999 221125_WJC_METTL3_EV_vs_WT_F05.20078.20078.4 1.49E-08 18/102 R.EDK[136.11]SPIAPEELALVHNLR[166.11].K "sp|P51398|RT29_HUMAN,tr|V9GYA7|V9GYA7_HUMAN,tr|V9GYJ9|V9GYJ9_HUMAN,tr|V9GYW1|V9GYW1_HUMAN,tr|V9GZ03|V9GZ03_HUMAN,tr|V9GZ61|V9GZ61_HUMAN,tr|V9GYC9|V9GYC9_HUMAN,tr|V9GYL9|V9GYL9_HUMAN" 8 2048.1021 1.69 70802 20078 4 2048.10126 513.0328 "28S ribosomal protein S29, mitochondrial OS=Homo sapiens OX=9606 GN=DAP3 PE=1 SV=1" 4.83 3316.7 - 462371 - - - -0.4219 - 3.145 0.501 - 355.5 1 2 1 -0.0009 18 0 0 0 4.34E+06 2.57E+06 - - - 3.979 1 221125_WJC_METTL3_EV_vs_WT_F05.20080.20080.3 1.11E-08 18/96 R.C[160.03]VLLSNLSSTSHVPEVDPGSAELQK.V "sp|P49327|FAS_HUMAN,tr|A0A0U1RQF0|A0A0U1RQF0_HUMAN" 2 2666.3221 0.66 70804 20080 3 2666.32339 889.7813 Fatty acid synthase OS=Homo sapiens OX=9606 GN=FASN PE=1 SV=3 4.65 3316.9 - 995572 - - - 0.4666 - 3.105 0.588 - 176.6 1 2 0 0.0012 25 0 0 0 1.35E+07 2.04E+07 - - - 7.7019 0.9989 221125_WJC_METTL3_EV_vs_WT_F05.20082.20082.3 0.000135 Nov-64 R.GKYSEVFEAINITNNEK.V "sp|P68400|CSK21_HUMAN,sp|Q8NEV1|CSK23_HUMAN,tr|A0A2R8YCK2|A0A2R8YCK2_HUMAN,tr|A0A2R8YFU2|A0A2R8YFU2_HUMAN,tr|V9GYA2|V9GYA2_HUMAN,tr|A0A2R8YEW1|A0A2R8YEW1_HUMAN,tr|A0A2R8Y4D6|A0A2R8Y4D6_HUMAN,tr|A0A2R8YD58|A0A2R8YD58_HUMAN,tr|A0A2R8YF43|A0A2R8YF43_HUMAN,tr|A0A2R8Y5A0|A0A2R8Y5A0_HUMAN,tr|A0A2R8YDY7|A0A2R8YDY7_HUMAN,tr|A0A2R8YF47|A0A2R8YF47_HUMAN,tr|A0A2R8Y4H0|A0A2R8Y4H0_HUMAN,tr|A0A2R8Y7T1|A0A2R8Y7T1_HUMAN,tr|A0A2R8YDP2|A0A2R8YDP2_HUMAN,tr|A0A2R8Y797|A0A2R8Y797_HUMAN,tr|A0A2R8YEL7|A0A2R8YEL7_HUMAN,tr|V9GY80|V9GY80_HUMAN,tr|E7EU96|E7EU96_HUMAN,tr|A0A2R8Y3W6|A0A2R8Y3W6_HUMAN" 20 1954.9636 1.2 70806 20082 3 1954.967525 652.6618 Casein kinase II subunit alpha OS=Homo sapiens OX=9606 GN=CSNK2A1 PE=1 SV=1 4.79 3317.2 - 483212 - - - 1.9965 - 2.208 0.398 - 152 1 2 1 0.0039 17 0 0 0 1.56E+07 1.31E+07 - - - 4.9773 0.9997 221125_WJC_METTL3_EV_vs_WT_F05.20084.20084.4 7.05E-06 18/102 R.EDKSPIAPEELALVHNLR.K "sp|P51398|RT29_HUMAN,tr|V9GYA7|V9GYA7_HUMAN,tr|V9GYJ9|V9GYJ9_HUMAN,tr|V9GYW1|V9GYW1_HUMAN,tr|V9GZ03|V9GZ03_HUMAN,tr|V9GZ61|V9GZ61_HUMAN,tr|V9GYC9|V9GYC9_HUMAN,tr|V9GYL9|V9GYL9_HUMAN" 8 2030.0797 1.69 70808 20084 4 2030.081375 508.5272 "28S ribosomal protein S29, mitochondrial OS=Homo sapiens OX=9606 GN=DAP3 PE=1 SV=1" 4.83 3317.4 - 348553 - - - 0.8477 - 3.057 0.437 - 314.6 1 2 1 0.0017 18 0 0 0 4.34E+06 2.57E+06 - - - 3.412 0.9999 221125_WJC_METTL3_EV_vs_WT_F05.20092.20092.3 5.46E-06 Sep-84 K.VTINDLNENSVTLIQENC[160.03]HLNK[136.11].L sp|Q7Z2T5|TRM1L_HUMAN 1 2575.2792 0.5 70814 20092 3 2575.275297 859.4337 TRMT1-like protein OS=Homo sapiens OX=9606 GN=TRMT1L PE=1 SV=2 4.65 3318.5 - 321453 - - - -1.5024 - 2.239 0.495 - 74.6 1 2 0 -0.0039 22 0 0 0 1.52E+06 3.01E+06 - - - 5.9686 0.9999 221125_WJC_METTL3_EV_vs_WT_F05.20093.20093.3 8.77E-06 Oct-56 R.GHLESSLLSHLVDPK[136.11].D "sp|O94766|B3GA3_HUMAN,tr|G3V150|G3V150_HUMAN" 2 1638.8821 1.17 70815 20093 3 1638.88085 547.3013 Galactosylgalactosylxylosylprotein 3-beta-glucuronosyltransferase 3 OS=Homo sapiens OX=9606 GN=B3GAT3 PE=1 SV=2 5.99 3318.6 - 276118 - - - -0.745 - 2.162 0.452 - 100.9 1 2 0 -0.0012 15 0 0 0 4.92E+06 4.22E+06 - - - 5.5909 1 221125_WJC_METTL3_EV_vs_WT_F05.20097.20097.3 1.05E-11 27/80 K.WQHDLFDSGFGGGAGVETGGK.L "sp|Q86V81|THOC4_HUMAN,tr|E9PB61|E9PB61_HUMAN" 2 2120.9552 0.7 70817 20097 3 2120.955326 707.9923 THO complex subunit 4 OS=Homo sapiens OX=9606 GN=ALYREF PE=1 SV=3 4.54 3319.1 - 2.62E+06 - - - 0.0679 - 4.093 0.675 - 985.8 1 2 0 0.0001 21 0 0 0 6.19E+07 8.86E+07 - - - 9.4442 1 221125_WJC_METTL3_EV_vs_WT_F05.20101.20101.3 1.53E-07 Dec-56 R.GHLESSLLSHLVDPK.D "sp|O94766|B3GA3_HUMAN,tr|G3V150|G3V150_HUMAN" 2 1630.8679 1.21 70821 20101 3 1630.87023 544.6299 Galactosylgalactosylxylosylprotein 3-beta-glucuronosyltransferase 3 OS=Homo sapiens OX=9606 GN=B3GAT3 PE=1 SV=2 5.99 3319.6 - 339894 - - - 1.4465 - 2.578 0.512 - 144.3 1 2 0 0.0024 15 0 0 0 5.10E+06 4.22E+06 - - - 6.7187 1 221125_WJC_METTL3_EV_vs_WT_F05.20102.20102.2 3.39E-14 15/38 R.GSGSQSSVPSVDQFTGVGIR[166.11].V sp|Q9UQE7|SMC3_HUMAN 1 1973.9682 1.84 70822 20102 2 1973.966766 987.9914 Structural maintenance of chromosomes protein 3 OS=Homo sapiens OX=9606 GN=SMC3 PE=1 SV=2 5.84 3319.7 - 315982 - - - -0.728 - 3.478 0.72 - 231.5 1 2 0 -0.0014 20 0 0 0 8.41E+06 4.57E+06 - - - 7.4229 0.997 221125_WJC_METTL3_EV_vs_WT_F05.20104.20104.4 4.26E-05 13/90 R.SPSELFAQHIVTIVHH.V "sp|Q9Y2W1|TR150_HUMAN,tr|A0A3B3ITZ9|A0A3B3ITZ9_HUMAN" 2 1813.9475 - 70824 20104 4 1813.944993 454.4942 Thyroid hormone receptor-associated protein 3 OS=Homo sapiens OX=9606 GN=THRAP3 PE=1 SV=2 6.2 3320 - 284264 - - - -1.392 - 2.725 0.532 - 129.6 1 1 0 -0.0025 16 0 0 0 - - - - - 4.209 1 221125_WJC_METTL3_EV_vs_WT_F05.20105.20105.3 8.06E-07 Dec-64 K.STPKPIPILAAGFC[160.03]SDK.M "sp|Q15061|WDR43_HUMAN,tr|C9IZK7|C9IZK7_HUMAN" 2 1800.9444 0.67 70825 20105 3 1800.946042 601.3221 WD repeat-containing protein 43 OS=Homo sapiens OX=9606 GN=WDR43 PE=1 SV=3 7.92 3320.1 - 225147 - - - 0.9079 - 2.727 0.563 - 228.6 1 2 0 0.0016 17 0 0 0 4.15E+06 6.22E+06 - - - 7.3508 0.9991 221125_WJC_METTL3_EV_vs_WT_F05.20108.20108.3 0.00543 Jun-84 K.DLGLSESGEDVNAAILDESGK[136.11]K[136.11].F "sp|P13667|PDIA4_HUMAN,tr|A0A499FI48|A0A499FI48_HUMAN" 2 2262.1198 1.12 70827 20108 3 2262.122877 755.0472 Protein disulfide-isomerase A4 OS=Homo sapiens OX=9606 GN=PDIA4 PE=1 SV=2 4.02 3320.5 - 76860.6 - - - 1.3598 - 1.774 0.328 - 34.8 1 2 0 0.0031 22 0 0 0 1.14E+07 1.02E+07 - - - 3.5551 1 221125_WJC_METTL3_EV_vs_WT_F05.20109.20109.3 0.000349 18/80 R.AGPSYSMPVHAAVQMTTEQLK.T "sp|Q14527|HLTF_HUMAN,tr|A0A0C4DGA6|A0A0C4DGA6_HUMAN" 2 2245.0871 4.41 70828 20109 3 2245.090576 749.3697 Helicase-like transcription factor OS=Homo sapiens OX=9606 GN=HLTF PE=1 SV=2 6.79 3320.6 - 608099 - - - 1.5376 - 3.903 0.558 - 372.5 1 2 0 0.0035 21 0 0 0 1.45E+07 3.30E+06 - - - 8.0249 0.9607 221125_WJC_METTL3_EV_vs_WT_F05.20110.20110.4 0.0377 11/144 R.C[160.03]VLLSNLSSTSHVPEVDPGSAELQK[136.11].V "sp|P49327|FAS_HUMAN,tr|A0A0U1RQF0|A0A0U1RQF0_HUMAN" 2 2674.3363 0.55 70829 20110 4 2674.33578 669.5914 Fatty acid synthase OS=Homo sapiens OX=9606 GN=FASN PE=1 SV=3 4.65 3320.7 - 448433 - - - -0.2116 - 1.7 0.15 - 59.5 1 2 0 -0.0006 25 0 0 0 1.00E+06 1.84E+06 - - - 0.7002 0.9999 221125_WJC_METTL3_EV_vs_WT_F05.20113.20113.3 1.88E-11 17/96 K.TGADTTAAGPLFQQR[166.11]PYPSPGAVLR[166.11].A "sp|O60828|PQBP1_HUMAN,tr|H7C053|H7C053_HUMAN" 2 2590.3407 0.66 70832 20113 3 2590.341577 864.4542 Polyglutamine-binding protein 1 OS=Homo sapiens OX=9606 GN=PQBP1 PE=1 SV=1 8.41 3321.1 - 335507 - - - 0.3482 - 3.289 0.411 - 210.2 1 2 0 0.0009 25 0 0 0 2.77E+06 4.17E+06 - - - 5.8611 0.9999 221125_WJC_METTL3_EV_vs_WT_F05.20118.20118.3 3.47E-05 13/96 K.TGADTTAAGPLFQQRPYPSPGAVLR.A "sp|O60828|PQBP1_HUMAN,tr|H7C053|H7C053_HUMAN" 2 2570.3241 0.66 70837 20118 3 2570.333868 857.782 Polyglutamine-binding protein 1 OS=Homo sapiens OX=9606 GN=PQBP1 PE=1 SV=1 8.41 3321.8 - 227873 - - - 3.7867 - 2.636 0.556 - 136.1 1 2 0 0.0097 25 0 0 0 2.77E+06 4.17E+06 - - - 6.9661 1 221125_WJC_METTL3_EV_vs_WT_F05.20125.20125.3 3.55E-12 22/84 K.ELVNLIDNHQVTVISGETGC[160.03]GK.T "sp|Q9H2U1|DHX36_HUMAN,tr|E7EWK3|E7EWK3_HUMAN" 2 2382.1849 1.16 70842 20125 3 2382.189534 795.0689 ATP-dependent DNA\RNA helicase DHX36 OS=Homo sapiens OX=9606 GN=DHX36 PE=1 SV=2 4.65 3322.7 - 757960 - - - 1.9352 - 3.521 0.67 - 584.6 1 2 0 0.0046 22 0 0 0 7.07E+06 6.08E+06 - - - 8.9928 1 221125_WJC_METTL3_EV_vs_WT_F05.20126.20126.3 3.30E-10 15/56 R.QHSNSNMVIMLIGNK.S "sp|P61019|RAB2A_HUMAN,tr|H7C125|H7C125_HUMAN,tr|E9PKL7|E9PKL7_HUMAN" 3 1684.8389 1.43 70843 20126 3 1684.841632 562.6202 Ras-related protein Rab-2A OS=Homo sapiens OX=9606 GN=RAB2A PE=1 SV=1 8.76 3322.8 - 668773 - - - 1.6245 - 2.792 0.614 - 375.6 1 2 0 0.0027 15 0 0 0 8.74E+06 6.12E+06 - - - 8.0639 1 221125_WJC_METTL3_EV_vs_WT_F05.20127.20127.3 2.08E-09 15/56 K.DQFGFINYEVGDSK[136.11]K[136.11].L "sp|O75534|CSDE1_HUMAN,tr|E9PLT0|E9PLT0_HUMAN" 2 1761.8545 0.43 70844 20127 3 1761.855686 588.2921 Cold shock domain-containing protein E1 OS=Homo sapiens OX=9606 GN=CSDE1 PE=1 SV=2 4.56 3322.9 - 622817 - - - 0.693 - 2.556 0.641 - 304.3 1 2 0 0.0012 15 0 0 0 4.71E+06 1.10E+07 - - - 8.1349 0.9995 221125_WJC_METTL3_EV_vs_WT_F05.20128.20128.2 2.46E-08 13/28 R.DASGVTFTWTPSSGK.S "sp|P01876|IGHA1_HUMAN,tr|A0A286YEY1|A0A286YEY1_HUMAN" 2 1539.7205 12.97 70845 20128 2 1539.725413 770.8675 Immunoglobulin heavy constant alpha 1 OS=Homo sapiens OX=9606 GN=IGHA1 PE=1 SV=2 5.84 3323.1 - 426242 - - - 3.1662 - 2.616 0.516 - 404.7 1 2 0 0.0049 15 0 0 0 2.30E+06 1.78E+05 - - - 5.2149 1 221125_WJC_METTL3_EV_vs_WT_F05.20129.20129.3 2.60E-08 18/76 K.SESEVEEAAAIIAQR[166.11]PDNPR[166.11].E "sp|Q16643|DREB_HUMAN,tr|D6R9Q9|D6R9Q9_HUMAN,tr|D6R9W4|D6R9W4_HUMAN" 3 2201.0827 1.84 70846 20129 3 2201.084854 734.7015 Drebrin OS=Homo sapiens OX=9606 GN=DBN1 PE=1 SV=4 4.25 3323.2 - 370277 - - - 0.9654 - 3.073 0.621 - 449.3 1 2 0 0.0021 20 0 0 0 3.46E+06 1.88E+06 - - - 8.1865 1 221125_WJC_METTL3_EV_vs_WT_F05.20130.20130.3 4.00E-12 18/80 R.AGPSYSMPVHAAVQMTTEQLK[136.11].T "sp|Q14527|HLTF_HUMAN,tr|A0A0C4DGA6|A0A0C4DGA6_HUMAN" 2 2253.1013 4.11 70847 20130 3 2253.113126 752.0411 Helicase-like transcription factor OS=Homo sapiens OX=9606 GN=HLTF PE=1 SV=2 6.79 3323.4 - 367519 - - - 5.2381 - 3.896 0.613 - 538.6 1 2 0 0.0118 21 0 0 0 1.28E+07 3.12E+06 - - - 8.6315 0.9998 221125_WJC_METTL3_EV_vs_WT_F05.20133.20133.3 0.00288 15/92 R.EQFDTLTPEPPVDPNQEVPPGPPR.F "sp|Q6PKG0|LARP1_HUMAN,tr|A0A0B4J210|A0A0B4J210_HUMAN,tr|H0YC33|H0YC33_HUMAN,tr|E5RH50|E5RH50_HUMAN" 4 2655.2817 2.77 70850 20133 3 2655.271867 886.1012 La-related protein 1 OS=Homo sapiens OX=9606 GN=LARP1 PE=1 SV=2 3.83 3323.7 - 331436 - - - -3.6885 - 2.575 0.502 - 132 1 2 0 -0.0098 24 0 0 0 2.36E+07 8.52E+06 - - - 6.3309 0.9548 221125_WJC_METTL3_EV_vs_WT_F05.20137.20137.4 0.946 Jul-84 R.GHLESSLLSHLVDPK[136.11].D "sp|O94766|B3GA3_HUMAN,tr|G3V150|G3V150_HUMAN" 2 1638.8821 0.96 70854 20137 4 1638.883831 410.7278 Galactosylgalactosylxylosylprotein 3-beta-glucuronosyltransferase 3 OS=Homo sapiens OX=9606 GN=B3GAT3 PE=1 SV=2 5.99 3324.3 - 178523 - - - 1.0739 - 1.407 0.15 - 38.2 1 2 0 0.0018 15 0 0 0 1.07E+06 1.12E+06 - - - 0.6533 0.9997 221125_WJC_METTL3_EV_vs_WT_F05.20139.20139.3 0.000629 Aug-36 R.KDAEDWFFSK.T "sp|Q04695|K1C17_HUMAN,tr|K7ESE1|K7ESE1_HUMAN,tr|F5GWP8|F5GWP8_HUMAN" 3 1271.5823 999 70856 20139 3 1271.583248 424.868 "Keratin, type I cytoskeletal 17 OS=Homo sapiens OX=9606 GN=KRT17 PE=1 SV=2" 4.56 3324.5 - 148356 - - - 0.7825 - 1.528 0.403 - 108.4 1 2 0 0.001 10 0 0 0 6.92E+05 0.00E+00 - - - 4.2709 1 221125_WJC_METTL3_EV_vs_WT_F05.20141.20141.2 4.77E-12 16/40 K.WQHDLFDSGFGGGAGVETGGK[136.11].L "sp|Q86V81|THOC4_HUMAN,tr|E9PB61|E9PB61_HUMAN" 2 2128.9694 -1 70858 20141 2 2128.966035 1065.492 THO complex subunit 4 OS=Homo sapiens OX=9606 GN=ALYREF PE=1 SV=3 4.54 3324.8 - 110864 - - - -1.5721 - 3.557 0.714 - 666.1 1 2 0 -0.0033 21 0 0 0 0.00E+00 0.00E+00 - - - 7.4332 1 221125_WJC_METTL3_EV_vs_WT_F05.20148.20148.3 1.09E-08 13/56 R.QHSNSNMVIMLIGNK[136.11].S "sp|P61019|RAB2A_HUMAN,tr|H7C125|H7C125_HUMAN,tr|E9PKL7|E9PKL7_HUMAN" 3 1692.8531 1.37 70864 20148 3 1692.855466 565.2916 Ras-related protein Rab-2A OS=Homo sapiens OX=9606 GN=RAB2A PE=1 SV=1 8.76 3325.5 - 1.15E+06 - - - 1.4006 - 2.463 0.606 - 302 1 2 0 0.0024 15 0 0 0 8.16E+06 5.96E+06 - - - 7.6477 0.9999 221125_WJC_METTL3_EV_vs_WT_F05.20149.20149.3 1.89E-06 15/56 K.DQFGFINYEVGDSKK.L "sp|O75534|CSDE1_HUMAN,tr|E9PLT0|E9PLT0_HUMAN" 2 1745.8261 0.43 70865 20149 3 1745.830969 582.9493 Cold shock domain-containing protein E1 OS=Homo sapiens OX=9606 GN=CSDE1 PE=1 SV=2 4.56 3325.6 - 912597 - - - 2.809 - 2.425 0.591 - 272.6 1 2 0 0.0049 15 0 0 0 4.71E+06 1.10E+07 - - - 7.4392 0.9999 221125_WJC_METTL3_EV_vs_WT_F05.20150.20150.3 0.248 17/52 K.ILLAELEQLKGQGK.S "sp|P08670|VIME_HUMAN,tr|B0YJC4|B0YJC4_HUMAN,tr|A0A1B0GTT5|A0A1B0GTT5_HUMAN" 3 1538.9032 1.87 70866 20150 3 1538.903991 513.975 Vimentin OS=Homo sapiens OX=9606 GN=VIM PE=1 SV=4 6.14 3325.7 - 401714 - - - 0.5179 - 3.232 0.458 - 393.9 1 2 1 0.0008 14 0 0 0 3.69E+06 1.97E+06 - - - 6.7636 0.9897 221125_WJC_METTL3_EV_vs_WT_F05.20151.20151.4 0.000413 13/102 R.ELQELVQYPVEHPDKFLK.F "sp|P55072|TERA_HUMAN,tr|A0A7P0Z4C6|A0A7P0Z4C6_HUMAN,tr|A0A7P0T8Q5|A0A7P0T8Q5_HUMAN,tr|C9JUP7|C9JUP7_HUMAN,tr|A0A7P0TAW3|A0A7P0TAW3_HUMAN,tr|A0A7I2V540|A0A7I2V540_HUMAN,tr|A0A7P0T8A3|A0A7P0T8A3_HUMAN,tr|A0A7P0TAQ1|A0A7P0TAQ1_HUMAN" 8 2211.1576 1.4 70867 20151 4 2211.167318 553.7967 Transitional endoplasmic reticulum ATPase OS=Homo sapiens OX=9606 GN=VCP PE=1 SV=4 4.83 3325.9 - 349232 - - - 4.4086 - 2.352 0.355 - 125 1 2 1 0.0097 18 0 0 0 2.52E+06 1.80E+06 - - - 2.6062 0.9957 221125_WJC_METTL3_EV_vs_WT_F05.20156.20156.4 0.0283 Jul-84 R.GHLESSLLSHLVDPK.D "sp|O94766|B3GA3_HUMAN,tr|G3V150|G3V150_HUMAN" 2 1630.8679 0.92 70872 20156 4 1630.86983 408.7242 Galactosylgalactosylxylosylprotein 3-beta-glucuronosyltransferase 3 OS=Homo sapiens OX=9606 GN=B3GAT3 PE=1 SV=2 5.99 3326.5 - 229900 - - - 1.2012 - 1.564 0.24 - 34 1 2 0 0.002 15 0 0 0 1.15E+06 1.25E+06 - - - 1.4744 1 221125_WJC_METTL3_EV_vs_WT_F05.20164.20164.3 2.78E-11 23/80 K.WQHDLFDSGFGGGAGVETGGK[136.11].L "sp|Q86V81|THOC4_HUMAN,tr|E9PB61|E9PB61_HUMAN" 2 2128.9694 0.7 70879 20164 3 2128.971636 710.6637 THO complex subunit 4 OS=Homo sapiens OX=9606 GN=ALYREF PE=1 SV=3 4.54 3327.6 - 5.19E+06 - - - 1.0587 - 3.173 0.595 - 638 1 2 0 0.0023 21 0 0 0 6.19E+07 8.86E+07 - - - 7.9413 1 221125_WJC_METTL3_EV_vs_WT_F05.20166.20166.3 4.24E-12 23/76 K.EQVTNVGGAVVTGVTAVAQK.T "sp|P37840|SYUA_HUMAN,tr|A0A669KB41|A0A669KB41_HUMAN,tr|A0A669KBH5|A0A669KBH5_HUMAN,tr|H6UYS7|H6UYS7_HUMAN,tr|E7EPV7|E7EPV7_HUMAN" 5 1927.0375 1.67 70881 20166 3 1927.041925 643.3531 Alpha-synuclein OS=Homo sapiens OX=9606 GN=SNCA PE=1 SV=1 6.1 3327.8 - 874607 - - - 2.3196 - 3.952 0.563 - 864.9 1 2 0 0.0045 20 0 0 0 5.55E+08 3.32E+08 - - - 8.1496 1 221125_WJC_METTL3_EV_vs_WT_F05.20168.20168.3 1.78E-07 14/56 R.NK[136.11]EVTWEVLEGEVEK[136.11].E sp|P05455|LA_HUMAN 1 1803.9225 0.93 70883 20168 3 1803.924014 602.3148 Lupus La protein OS=Homo sapiens OX=9606 GN=SSB PE=1 SV=2 4.33 3328.1 - 448123 - - - 0.8143 - 3.199 0.597 - 356.4 1 2 1 0.0015 15 0 0 0 4.12E+06 4.45E+06 - - - 8.2298 0.9998 221125_WJC_METTL3_EV_vs_WT_F05.20169.20169.3 0.00393 Dec-52 K.ILLAELEQLK[136.11]GQGK[136.11].S "sp|P08670|VIME_HUMAN,tr|B0YJC4|B0YJC4_HUMAN,tr|A0A1B0GTT5|A0A1B0GTT5_HUMAN" 3 1554.9316 1.87 70884 20169 3 1554.932693 519.3178 Vimentin OS=Homo sapiens OX=9606 GN=VIM PE=1 SV=4 6.14 3328.2 - 428462 - - - 0.7074 - 2.742 0.427 - 124.9 1 2 1 0.0011 14 0 0 0 3.69E+06 1.97E+06 - - - 5.9809 0.9977 221125_WJC_METTL3_EV_vs_WT_F05.20170.20170.4 8.46E-10 23/108 C.K[136.11]ILGSGISSSSVLHGMVFK[136.11].K sp|P50990|TCPQ_HUMAN 1 1962.0943 0.29 70885 20170 4 1962.097783 491.5309 T-complex protein 1 subunit theta OS=Homo sapiens OX=9606 GN=CCT8 PE=1 SV=4 10 3328.3 - 397658 - - - 1.7655 - 3.721 0.596 - 502.4 1 1 0 0.0035 19 0 0 0 2.25E+06 7.65E+06 - - - 4.8571 1 221125_WJC_METTL3_EV_vs_WT_F05.20171.20171.3 2.39E-07 14/80 K.DGSC[160.03]GVAYVVQEPGDYEVSVK.F "sp|P21333|FLNA_HUMAN,tr|A0A7P0NMY4|A0A7P0NMY4_HUMAN,tr|Q60FE5|Q60FE5_HUMAN,tr|H0Y5C6|H0Y5C6_HUMAN" 4 2257.0209 5.27 70886 20171 3 2257.023825 753.3476 Filamin-A OS=Homo sapiens OX=9606 GN=FLNA PE=1 SV=4 3.92 3328.5 - 396823 - - - 1.3053 - 2.825 0.633 - 183.4 1 2 0 0.0029 21 0 0 0 8.88E+06 1.69E+06 - - - 8.0863 0.9994 221125_WJC_METTL3_EV_vs_WT_F05.20172.20172.3 0.000773 Nov-72 K.GADFLVTEVENGGSLGSKK.G "sp|P14618|KPYM_HUMAN,tr|H3BQ34|H3BQ34_HUMAN,tr|B4DNK4|B4DNK4_HUMAN,tr|A0A804F6T5|A0A804F6T5_HUMAN,tr|H3BTN5|H3BTN5_HUMAN,tr|A0A804F729|A0A804F729_HUMAN" 6 1906.9636 0.65 70887 20172 3 1906.969028 636.6618 Pyruvate kinase PKM OS=Homo sapiens OX=9606 GN=PKM PE=1 SV=4 4.68 3328.6 - 328175 - - - 2.8349 - 2.215 0.377 - 128.6 1 2 0 0.0054 19 0 0 0 1.15E+06 1.78E+06 - - - 4.6955 0.9999 221125_WJC_METTL3_EV_vs_WT_F05.20174.20174.3 7.55E-09 14/80 K.AQLK[136.11]DPQGPGPGLEAFVSAAK[136.11].K sp|O60287|NPA1P_HUMAN 1 2096.1237 0.99 70889 20174 3 2096.129081 699.7152 Nucleolar pre-ribosomal-associated protein 1 OS=Homo sapiens OX=9606 GN=URB1 PE=1 SV=4 6.11 3328.8 - 286023 - - - 2.5652 - 3.474 0.611 - 198.3 1 2 1 0.0054 21 0 0 0 1.64E+06 1.67E+06 - - - 8.3361 1 221125_WJC_METTL3_EV_vs_WT_F05.20180.20180.3 4.58E-05 18/76 K.EQVTNVGGAVVTGVTAVAQK[136.11].T "sp|P37840|SYUA_HUMAN,tr|A0A669KB41|A0A669KB41_HUMAN,tr|A0A669KBH5|A0A669KBH5_HUMAN,tr|H6UYS7|H6UYS7_HUMAN,tr|E7EPV7|E7EPV7_HUMAN" 5 1935.0517 1.67 70893 20180 3 1935.054116 646.0245 Alpha-synuclein OS=Homo sapiens OX=9606 GN=SNCA PE=1 SV=1 6.1 3329.6 - 4.17E+06 - - - 1.2718 - 3.535 0.546 - 426.8 1 2 0 0.0025 20 0 0 0 5.55E+08 3.32E+08 - - - 7.6901 1 221125_WJC_METTL3_EV_vs_WT_F05.20182.20182.2 4.02E-15 22/38 K.EQVTNVGGAVVTGVTAVAQK.T "sp|P37840|SYUA_HUMAN,tr|A0A669KB41|A0A669KB41_HUMAN,tr|A0A669KBH5|A0A669KBH5_HUMAN,tr|H6UYS7|H6UYS7_HUMAN,tr|E7EPV7|E7EPV7_HUMAN" 5 1927.0375 1.64 70895 20182 2 1927.040714 964.526 Alpha-synuclein OS=Homo sapiens OX=9606 GN=SNCA PE=1 SV=1 6.1 3329.9 - 1.00E+06 - - - 1.6912 - 4.426 0.732 - 1380.8 1 2 0 0.0033 20 0 0 0 1.33E+08 8.08E+07 - - - 8.1036 1 221125_WJC_METTL3_EV_vs_WT_F05.20183.20183.2 1.43E-09 20/38 K.EQVTNVGGAVVTGVTAVAQK[136.11].T "sp|P37840|SYUA_HUMAN,tr|A0A669KB41|A0A669KB41_HUMAN,tr|A0A669KBH5|A0A669KBH5_HUMAN,tr|H6UYS7|H6UYS7_HUMAN,tr|E7EPV7|E7EPV7_HUMAN" 5 1935.0517 1.64 70896 20183 2 1935.052872 968.5331 Alpha-synuclein OS=Homo sapiens OX=9606 GN=SNCA PE=1 SV=1 6.1 3330 - 873050 - - - 0.6289 - 4.142 0.666 - 1071.5 1 2 0 0.0012 20 0 0 0 1.33E+08 8.08E+07 - - - 7.4537 0.9996 221125_WJC_METTL3_EV_vs_WT_F05.20186.20186.3 4.53E-05 13/44 R.AR[166.11]FEELNADLFR[166.11].G "sp|P54652|HSP72_HUMAN,sp|P11142|HSP7C_HUMAN,tr|E9PNE6|E9PNE6_HUMAN,tr|A8K7Q2|A8K7Q2_HUMAN,tr|E9PKE3|E9PKE3_HUMAN,tr|E9PN89|E9PN89_HUMAN" 6 1499.7636 0.18 70899 20186 3 1499.767878 500.9285 Heat shock-related 70 kDa protein 2 OS=Homo sapiens OX=9606 GN=HSPA2 PE=1 SV=1 4.68 3330.4 - 431171 - - - 2.8745 - 2.524 0.513 - 361.4 1 2 1 0.0043 12 0 0 0 6.95E+06 3.84E+07 - - - 6.8246 1 221125_WJC_METTL3_EV_vs_WT_F05.20188.20188.3 5.12E-08 21/72 C.K[136.11]ILGSGISSSSVLHGMVFK[136.11].K sp|P50990|TCPQ_HUMAN 1 1962.0943 0.25 70901 20188 3 1962.100374 655.0387 T-complex protein 1 subunit theta OS=Homo sapiens OX=9606 GN=CCT8 PE=1 SV=4 10 3330.7 - 423764 - - - 3.086 - 3.776 0.649 - 368.4 1 1 0 0.0061 19 0 0 0 1.36E+06 5.44E+06 - - - 9.0383 0.9997 221125_WJC_METTL3_EV_vs_WT_F05.20191.20191.3 7.47E-05 Nov-88 K.GLVNLQSGAPK[136.11]PEENPSLNIQFK[136.11].L sp|Q9Y2T2|AP3M1_HUMAN 1 2495.3355 0.7 70904 20191 3 2495.342212 832.7858 AP-3 complex subunit mu-1 OS=Homo sapiens OX=9606 GN=AP3M1 PE=1 SV=1 6.14 3331.1 - 195298 - - - 2.6946 - 2.048 0.455 - 76.1 1 2 0 0.0067 23 0 0 0 9.23E+05 1.33E+06 - - - 5.2927 0.9999 221125_WJC_METTL3_EV_vs_WT_F05.20196.20196.3 4.88E-10 19/96 R.IMPDSNDSPPAEREPGEVVDSLVGK.Q sp|Q9Y657|SPIN1_HUMAN 1 2637.2592 1.22 70907 20196 3 2637.264174 880.0937 Spindlin-1 OS=Homo sapiens OX=9606 GN=SPIN1 PE=1 SV=3 4.02 3331.8 - 1.12E+06 - - - 1.8819 - 3.159 0.619 - 315.5 1 2 1 0.005 25 0 0 0 2.89E+07 2.36E+07 - - - 8.0862 0.9998 221125_WJC_METTL3_EV_vs_WT_F05.20199.20199.4 3.35E-07 16/108 K.DLDVITIPSK[136.11]DVVMVHEPK[136.11].Q "sp|O00139|KIF2A_HUMAN,tr|D6R9M0|D6R9M0_HUMAN,tr|A0A6Q8PFA6|A0A6Q8PFA6_HUMAN,tr|A0A6Q8PGG1|A0A6Q8PGG1_HUMAN,tr|A0A6Q8PGH7|A0A6Q8PGH7_HUMAN,tr|A0A6Q8PG37|A0A6Q8PG37_HUMAN,tr|A0A6Q8PH57|A0A6Q8PH57_HUMAN" 7 2150.1628 1.59 70910 20199 4 2150.162685 538.548 Kinesin-like protein KIF2A OS=Homo sapiens OX=9606 GN=KIF2A PE=1 SV=3 4.66 3332.2 - 478080 - - - -0.0498 - 2.783 0.475 - 124.7 1 2 1 -0.0001 19 0 0 0 5.37E+06 3.37E+06 - - - 3.7066 0.9999 221125_WJC_METTL3_EV_vs_WT_F05.20200.20200.4 8.38E-09 15/108 K.QSMTLNLADPVGSLKPHLR.A sp|P05412|JUN_HUMAN 1 2076.115 3.36 70911 20200 4 2076.118475 520.036 Transcription factor AP-1 OS=Homo sapiens OX=9606 GN=JUN PE=1 SV=2 8.75 3332.3 - 315985 - - - 1.6767 - 2.915 0.486 - 187.1 1 2 0 0.0035 19 0 0 0 3.46E+06 1.03E+06 - - - 3.8171 1 221125_WJC_METTL3_EV_vs_WT_F05.20203.20203.3 1.43E-06 Sep-88 R.LIIQSSNGHITTTPTPTQFLC[160.03]PK.N sp|P05412|JUN_HUMAN 1 2553.3261 5.94 70914 20203 3 2553.32873 852.116 Transcription factor AP-1 OS=Homo sapiens OX=9606 GN=JUN PE=1 SV=2 8.23 3332.7 - 209746 - - - 1.0265 - 2.181 0.508 - 65.2 1 2 0 0.0026 23 0 0 0 3.32E+06 5.60E+05 - - - 6.0323 0.9998 221125_WJC_METTL3_EV_vs_WT_F05.20204.20204.3 0.000138 Sep-44 R.DVDFELIK[136.11]VEGK[136.11].V "sp|P48643|TCPE_HUMAN,tr|E9PCA1|E9PCA1_HUMAN,tr|B7ZAR1|B7ZAR1_HUMAN,tr|E7ENZ3|E7ENZ3_HUMAN" 4 1406.7628 0.54 70915 20204 3 1406.763521 469.9282 T-complex protein 1 subunit epsilon OS=Homo sapiens OX=9606 GN=CCT5 PE=1 SV=1 4.32 3332.8 - 127124 - - - 0.5147 - 1.752 0.528 - 85 1 2 1 0.0007 12 0 0 0 1.18E+06 2.18E+06 - - - 5.9808 0.8164 221125_WJC_METTL3_EV_vs_WT_F05.20206.20206.3 0.367 Jun-64 K.GHTNAGDAIYEVVSLQR[166.11].E "sp|Q5R372|RBG1L_HUMAN,tr|A0A0U1RRM5|A0A0U1RRM5_HUMAN,tr|A0A0C4DG54|A0A0C4DG54_HUMAN,tr|A0A804HKD7|A0A804HKD7_HUMAN" 4 1838.915 0.95 70917 20206 3 1838.91122 613.979 Rab GTPase-activating protein 1-like OS=Homo sapiens OX=9606 GN=RABGAP1L PE=1 SV=1 5.32 3333.1 - 101901 - - - -2.08 - 1.44 0.118 - 33.4 6 2 0 -0.0038 17 0 0 0 1.43E+06 1.50E+06 - - - 0.4156 0.9999 221125_WJC_METTL3_EV_vs_WT_F05.20209.20209.4 2.38E-06 20/108 K.DLDVITIPSKDVVMVHEPK.Q "sp|O00139|KIF2A_HUMAN,tr|D6R9M0|D6R9M0_HUMAN,tr|A0A6Q8PFA6|A0A6Q8PFA6_HUMAN,tr|A0A6Q8PGG1|A0A6Q8PGG1_HUMAN,tr|A0A6Q8PGH7|A0A6Q8PGH7_HUMAN,tr|A0A6Q8PG37|A0A6Q8PG37_HUMAN,tr|A0A6Q8PH57|A0A6Q8PH57_HUMAN" 7 2134.1344 1.61 70918 20209 4 2134.133934 534.5409 Kinesin-like protein KIF2A OS=Homo sapiens OX=9606 GN=KIF2A PE=1 SV=3 4.66 3333.5 - 503661 - - - -0.2146 - 3.102 0.55 - 181.3 1 2 1 -0.0005 19 0 0 0 5.44E+06 3.37E+06 - - - 4.396 1 221125_WJC_METTL3_EV_vs_WT_F05.20212.20212.3 4.38E-06 17/76 K.QFYDQALQQAVVDDDANNAK.A "sp|P60033|CD81_HUMAN,tr|E9PJK1|E9PJK1_HUMAN,tr|E9PRJ8|E9PRJ8_HUMAN,tr|E9PIF1|E9PIF1_HUMAN,tr|E9PM31|E9PM31_HUMAN,tr|H0YDL9|H0YDL9_HUMAN,tr|H0YDJ9|H0YDJ9_HUMAN,tr|A6NMH8|A6NMH8_HUMAN,tr|H0YEE2|H0YEE2_HUMAN" 9 2252.0346 1.63 70921 20212 3 2252.032182 751.6855 CD81 antigen OS=Homo sapiens OX=9606 GN=CD81 PE=1 SV=1 3.77 3333.8 - 467797 - - - -1.0537 - 3.052 0.476 - 130 1 2 0 -0.0024 20 0 0 0 9.86E+06 6.04E+06 - - - 6.5532 1 221125_WJC_METTL3_EV_vs_WT_F05.20214.20214.3 2.32E-07 13/92 K.IGSLGLGTGEDDDYVDDFNSTSHR.S "sp|O95684|CEP43_HUMAN,tr|A0A087WV25|A0A087WV25_HUMAN" 2 2569.1205 1.75 70923 20214 3 2569.117903 857.3808 Centrosomal protein 43 OS=Homo sapiens OX=9606 GN=CEP43 PE=1 SV=1 3.9 3334.1 - 316803 - - - -0.9988 - 2.749 0.604 - 129.1 1 2 0 -0.0026 24 0 0 0 2.54E+06 1.46E+06 - - - 7.622 1 221125_WJC_METTL3_EV_vs_WT_F05.20231.20231.3 0.00534 13/44 R.DISLDSELHDLR.L "sp|Q15643|TRIPB_HUMAN,tr|H0YJ97|H0YJ97_HUMAN" 2 1411.6943 1.08 70938 20231 3 1411.69528 471.5721 Thyroid receptor-interacting protein 11 OS=Homo sapiens OX=9606 GN=TRIP11 PE=1 SV=3 4.22 3336.4 - 261978 - - - 0.6779 - 2.507 0.442 - 169.3 1 2 0 0.001 12 0 0 0 1.51E+06 1.40E+06 - - - 6.0152 1 221125_WJC_METTL3_EV_vs_WT_F05.20233.20233.3 2.61E-07 Oct-56 R.DHINLPGFSGQNPLR.G "sp|P00491|PNPH_HUMAN,tr|G3V5M2|G3V5M2_HUMAN" 2 1663.8431 0.29 70940 20233 3 1663.841726 555.6216 Purine nucleoside phosphorylase OS=Homo sapiens OX=9606 GN=PNP PE=1 SV=2 6.74 3336.6 - 249888 - - - -0.7976 - 2.364 0.563 - 106.8 1 2 0 -0.0013 15 0 0 0 4.77E+06 1.62E+07 - - - 7.0615 0.9991 221125_WJC_METTL3_EV_vs_WT_F05.20236.20236.3 0.00326 Jul-64 K.GHTNAGDAIYEVVSLQR.E "sp|Q5R372|RBG1L_HUMAN,tr|A0A0U1RRM5|A0A0U1RRM5_HUMAN,tr|A0A0C4DG54|A0A0C4DG54_HUMAN,tr|A0A804HKD7|A0A804HKD7_HUMAN" 4 1828.9068 0.95 70943 20236 3 1828.905149 610.6429 Rab GTPase-activating protein 1-like OS=Homo sapiens OX=9606 GN=RABGAP1L PE=1 SV=1 5.32 3337 - 196133 - - - -0.8891 - 1.418 0.356 - 29.6 1 2 0 -0.0016 17 0 0 0 1.43E+06 1.50E+06 - - - 3.3909 0.9999 221125_WJC_METTL3_EV_vs_WT_F05.20239.20239.3 9.29E-06 18/52 R.NKLNDLEEALQQAK.E sp|P35908|K22E_HUMAN 1 1612.842 237.23 70944 20239 3 1612.842148 538.6213 "Keratin, type II cytoskeletal 2 epidermal OS=Homo sapiens OX=9606 GN=KRT2 PE=1 SV=2" 4.68 3337.4 - 3.45E+06 - - - 0.0608 - 3.723 0.464 - 614.8 1 2 1 0.0001 14 0 0 0 5.22E+08 2.20E+06 - - - 7.2065 0.986 221125_WJC_METTL3_EV_vs_WT_F05.20241.20241.3 4.91E-05 13/48 L.DGIHLLDPDVVAR[166.11].F sp|Q86U44|MTA70_HUMAN 1 1428.76 0.01 70946 20241 3 1428.758259 477.2606 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 4.41 3337.6 - 717607 - - - -1.2521 - 2.646 0.345 - 332.3 1 1 0 -0.0018 13 0 0 0 6.21E+04 8.42E+06 - - - 5.0241 0.9999 221125_WJC_METTL3_EV_vs_WT_F05.20245.20245.3 0.000111 Dec-76 K.RSSPAAFINPPIGTVTPALK.L "sp|Q9BY77|PDIP3_HUMAN,tr|F6VRR5|F6VRR5_HUMAN,tr|F8WCX5|F8WCX5_HUMAN,tr|Q6R954|Q6R954_HUMAN,tr|Q8WUT1|Q8WUT1_HUMAN,tr|F8WEE2|F8WEE2_HUMAN" 6 2036.1419 1.87 70950 20245 3 2036.138157 679.7212 Polymerase delta-interacting protein 3 OS=Homo sapiens OX=9606 GN=POLDIP3 PE=1 SV=2 11 3338.2 - 258442 - - - -1.8191 - 2.285 0.434 - 151.4 1 2 0 -0.0037 20 0 0 0 5.31E+06 2.84E+06 - - - 5.3824 0.9999 221125_WJC_METTL3_EV_vs_WT_F05.20249.20249.3 6.58E-05 Dec-76 K.R[166.11]SSPAAFINPPIGTVTPALK[136.11].L "sp|Q9BY77|PDIP3_HUMAN,tr|F6VRR5|F6VRR5_HUMAN,tr|F8WCX5|F8WCX5_HUMAN,tr|Q6R954|Q6R954_HUMAN,tr|Q8WUT1|Q8WUT1_HUMAN,tr|F8WEE2|F8WEE2_HUMAN" 6 2054.1643 1.87 70954 20249 3 2054.164454 685.7287 Polymerase delta-interacting protein 3 OS=Homo sapiens OX=9606 GN=POLDIP3 PE=1 SV=2 11 3338.7 - 169005 - - - 0.0599 - 2.398 0.466 - 125.2 1 2 0 0.0001 20 0 0 0 5.31E+06 2.84E+06 - - - 5.8573 0.9999 221125_WJC_METTL3_EV_vs_WT_F05.20250.20250.4 0.00917 13/84 K.DLFIGDVIHNAGPHR.D sp|Q9NY97|B3GN2_HUMAN 1 1659.8481 1.53 70955 20250 4 1659.846612 415.9693 "N-acetyllactosaminide beta-1,3-N-acetylglucosaminyltransferase 2 OS=Homo sapiens OX=9606 GN=B3GNT2 PE=1 SV=2" 5.98 3338.8 - 159847 - - - -0.9194 - 2.394 0.43 - 108 1 2 0 -0.0015 15 0 0 0 2.53E+06 1.65E+06 - - - 3.2807 1 221125_WJC_METTL3_EV_vs_WT_F05.20253.20253.2 2.70E-10 21/26 R.NKLNDLEEALQQAK.E sp|P35908|K22E_HUMAN 1 1612.842 999 70956 20253 2 1612.844086 807.4283 "Keratin, type II cytoskeletal 2 epidermal OS=Homo sapiens OX=9606 GN=KRT2 PE=1 SV=2" 4.68 3339.2 - 1.57E+06 - - - 1.2624 - 3.992 0.674 - 1864.6 1 2 1 0.002 14 0 0 0 8.32E+07 0.00E+00 - - - 7.4923 0.9997 221125_WJC_METTL3_EV_vs_WT_F05.20257.20257.4 0.0386 Sep-84 K.DLFIGDVIHNAGPHR[166.11].D sp|Q9NY97|B3GN2_HUMAN 1 1669.8564 1.65 70960 20257 4 1669.854549 418.4714 "N-acetyllactosaminide beta-1,3-N-acetylglucosaminyltransferase 2 OS=Homo sapiens OX=9606 GN=B3GNT2 PE=1 SV=2" 5.98 3339.7 - 196870 - - - -1.1133 - 2.118 0.359 - 46.4 1 2 0 -0.0019 15 0 0 0 2.64E+06 1.60E+06 - - - 2.6187 0.9602 221125_WJC_METTL3_EV_vs_WT_F05.20261.20261.3 6.00E-06 Sep-84 C.C[160.03]YKPEAPGC[160.03]EAPDHLQGLGVPI.- sp|Q8N5Z5|KCD17_HUMAN 1 2407.1301 6.02 70962 20261 3 2407.138279 803.384 BTB\POZ domain-containing protein KCTD17 OS=Homo sapiens OX=9606 GN=KCTD17 PE=1 SV=3 4.65 3340.3 - 557362 - - - 3.4178 - 1.891 0.486 - 30.8 1 1 0 0.0082 22 0 0 0 1.13E+07 1.88E+06 - - - 5.4666 0.9999 221125_WJC_METTL3_EV_vs_WT_F05.20265.20265.2 3.23E-06 30-Sep R.QLC[160.03]DNAGFDATNILNK[136.11].L sp|Q99832|TCPH_HUMAN 1 1800.8556 0.29 70966 20265 2 1800.855199 901.4351 T-complex protein 1 subunit eta OS=Homo sapiens OX=9606 GN=CCT7 PE=1 SV=2 4.21 3340.8 - 166266 - - - -0.2216 - 1.941 0.535 - 234.6 1 2 0 -0.0004 16 0 0 0 8.09E+05 2.82E+06 - - - 4.6229 0.9991 221125_WJC_METTL3_EV_vs_WT_F05.20267.20267.3 0.00145 Jul-60 R.QLC[160.03]DNAGFDATNILNK[136.11].L sp|Q99832|TCPH_HUMAN 1 1800.8556 3.24 70968 20267 3 1800.855258 601.2925 T-complex protein 1 subunit eta OS=Homo sapiens OX=9606 GN=CCT7 PE=1 SV=2 4.21 3341 - 164607 - - - -0.1888 - 1.55 0.333 - 57.1 1 2 0 -0.0003 16 0 0 0 4.71E+06 1.45E+06 - - - 3.377 1 221125_WJC_METTL3_EV_vs_WT_F05.20273.20273.3 1.68E-08 20/64 K.MLQAPESVLAEHYQDLR.R "sp|O00746|NDKM_HUMAN,tr|Q4TT34|Q4TT34_HUMAN,tr|H0Y6J0|H0Y6J0_HUMAN,tr|F2Z2X0|F2Z2X0_HUMAN,tr|A2IDC9|A2IDC9_HUMAN" 5 1998.9833 2.04 70972 20273 3 1998.989192 667.335 "Nucleoside diphosphate kinase, mitochondrial OS=Homo sapiens OX=9606 GN=NME4 PE=1 SV=1" 4.65 3341.9 - 500173 - - - 2.942 - 3.983 0.613 - 537.5 1 2 0 0.0059 17 0 0 0 9.99E+06 4.90E+06 - - - 8.8642 0.9999 221125_WJC_METTL3_EV_vs_WT_F05.20275.20275.3 3.60E-07 Dec-76 K.SGSDFTALGFSDVDHTYAQR.T "sp|Q9UL63|MKLN1_HUMAN,tr|C9J7E8|C9J7E8_HUMAN" 2 2172.9712 2.48 70974 20275 3 2172.975134 725.331 Muskelin OS=Homo sapiens OX=9606 GN=MKLN1 PE=1 SV=2 4.41 3342.1 - 255324 - - - 1.7985 - 2.824 0.49 - 152.2 1 2 0 0.0039 20 0 0 0 2.64E+06 1.06E+06 - - - 6.5205 0.9826 221125_WJC_METTL3_EV_vs_WT_F05.20277.20277.2 0.000194 May-40 R.SSGGSGGGPLSHFYSGSPTSY.F "tr|K7EQG2|K7EQG2_HUMAN,tr|E9PAU2|E9PAU2_HUMAN,tr|A0A087WZ13|A0A087WZ13_HUMAN" 3 1987.8548 - 70976 20277 2 1987.857554 994.9347 Uncharacterized protein (Fragment) OS=Homo sapiens OX=9606 PE=1 SV=1 6.46 3342.4 - 80462.6 - - - 1.3859 - 1.107 0.665 - 31.1 1 1 0 0.0028 21 0 0 0 - - - - - 4.2017 0.9978 221125_WJC_METTL3_EV_vs_WT_F05.20278.20278.4 0.0284 7/120 R.GR[166.11]LPLLLVANAGTAAVGHTDK[136.11].L "sp|Q6P996|PDXD1_HUMAN,sp|Q6P474|PDXD2_HUMAN,tr|J3KNK7|J3KNK7_HUMAN,tr|H3BNL6|H3BNL6_HUMAN,tr|Q86XE2|Q86XE2_HUMAN,tr|H3BND4|H3BND4_HUMAN" 6 2091.1919 3.44 70977 20278 4 2091.191777 523.8053 Pyridoxal-dependent decarboxylase domain-containing protein 1 OS=Homo sapiens OX=9606 GN=PDXDC1 PE=1 SV=2 8.75 3342.5 - 49557.7 - - - -0.0789 - 1.504 0.365 - 19.6 2 2 1 -0.0002 21 0 0 0 2.32E+06 6.73E+05 - - - 2.3084 1 221125_WJC_METTL3_EV_vs_WT_F05.20281.20281.3 8.13E-08 14/56 R.K[136.11]QSLGELIGTLNAAK[136.11].V sp|P60174|TPIS_HUMAN 1 1557.9061 1.38 70978 20281 3 1557.907986 520.3093 Triosephosphate isomerase OS=Homo sapiens OX=9606 GN=TPI1 PE=1 SV=4 8.59 3342.9 - 504930 - - - 1.2061 - 2.75 0.546 - 315 1 2 0 0.0019 15 0 0 0 1.41E+07 1.02E+07 - - - 7.2665 1 221125_WJC_METTL3_EV_vs_WT_F05.20283.20283.4 8.74E-08 19/114 R.GWTLNSAGYLLGPHAVGNHR.S sp|P22466|GALA_HUMAN 1 2119.0712 0.29 70980 20283 4 2119.07068 530.7751 Galanin peptides OS=Homo sapiens OX=9606 GN=GAL PE=1 SV=3 8.76 3343.2 - 406806 - - - -0.2242 - 4.05 0.484 - 358 1 2 0 -0.0005 20 0 0 0 4.05E+06 1.37E+07 - - - 3.9062 0.9996 221125_WJC_METTL3_EV_vs_WT_F05.20285.20285.3 7.03E-08 15/68 K.LGELSDKIGSTIDDTISK.F sp|Q14677|EPN4_HUMAN 1 1890.9786 1.18 70982 20285 3 1890.985707 631.3335 Clathrin interactor 1 OS=Homo sapiens OX=9606 GN=CLINT1 PE=1 SV=1 4.23 3343.5 - 266136 - - - 3.7568 - 2.941 0.606 - 340.8 1 2 1 0.0071 18 0 0 0 6.19E+06 5.25E+06 - - - 7.9805 0.9967 221125_WJC_METTL3_EV_vs_WT_F05.20286.20286.3 3.28E-05 Sep-48 K.LLQDFFNGK[136.11]ELNK[136.11].S "sp|P54652|HSP72_HUMAN,sp|P11142|HSP7C_HUMAN,sp|P17066|HSP76_HUMAN,tr|E9PNE6|E9PNE6_HUMAN,tr|A8K7Q2|A8K7Q2_HUMAN,tr|E9PKE3|E9PKE3_HUMAN,tr|E9PN89|E9PN89_HUMAN" 7 1580.8533 0.33 70983 20286 3 1580.860745 527.9584 Heat shock-related 70 kDa protein 2 OS=Homo sapiens OX=9606 GN=HSPA2 PE=1 SV=1 6.07 3343.6 - 167814 - - - 4.6823 - 2.176 0.464 - 69.1 1 2 1 0.0074 13 0 0 0 7.75E+05 2.34E+06 - - - 5.8191 1 221125_WJC_METTL3_EV_vs_WT_F05.20288.20288.3 3.21E-09 16/68 K.LGELSDK[136.11]IGSTIDDTISK[136.11].F sp|Q14677|EPN4_HUMAN 1 1907.007 1.2 70985 20288 3 1907.012274 636.6763 Clathrin interactor 1 OS=Homo sapiens OX=9606 GN=CLINT1 PE=1 SV=1 4.23 3343.8 - 145383 - - - 2.764 - 3.566 0.622 - 335.6 1 2 1 0.0053 18 0 0 0 6.29E+06 5.25E+06 - - - 8.6393 1 221125_WJC_METTL3_EV_vs_WT_F05.20294.20294.4 9.02E-07 15/96 K.QEVPSWLENMAYEHHYK.G "sp|O00571|DDX3X_HUMAN,sp|O15523|DDX3Y_HUMAN,tr|A0A2R8YFR4|A0A2R8YFR4_HUMAN,tr|A0A2R8YCW1|A0A2R8YCW1_HUMAN,tr|A0A2R8YDT5|A0A2R8YDT5_HUMAN,tr|A0A2R8Y645|A0A2R8Y645_HUMAN,tr|A0A2R8YF78|A0A2R8YF78_HUMAN,tr|A0A0D9SFB3|A0A0D9SFB3_HUMAN,tr|A0A2R8YFS5|A0A2R8YFS5_HUMAN,tr|A0A0D9SF53|A0A0D9SF53_HUMAN,tr|A0A087WVZ1|A0A087WVZ1_HUMAN,tr|A0A0J9YVQ7|A0A0J9YVQ7_HUMAN,tr|A0A2R8Y5G6|A0A2R8Y5G6_HUMAN,tr|A0A2R8Y7T2|A0A2R8Y7T2_HUMAN,tr|A0A0D9SG12|A0A0D9SG12_HUMAN,tr|F6S8Q4|F6S8Q4_HUMAN,tr|A0A2U3TZJ9|A0A2U3TZJ9_HUMAN,tr|A0A2R8Y4A4|A0A2R8Y4A4_HUMAN" 18 2159.9735 1.45 70989 20294 4 2159.975107 541.0006 ATP-dependent RNA helicase DDX3X OS=Homo sapiens OX=9606 GN=DDX3X PE=1 SV=3 5.33 3344.6 - 897778 - - - 0.7556 - 3.194 0.529 - 172.3 1 2 0 0.0016 17 0 0 0 1.07E+07 7.37E+06 - - - 4.2332 1 221125_WJC_METTL3_EV_vs_WT_F05.20295.20295.4 3.77E-08 19/96 K.QEVPSWLENMAYEHHYK[136.11].G "sp|O00571|DDX3X_HUMAN,sp|O15523|DDX3Y_HUMAN,tr|A0A2R8YFR4|A0A2R8YFR4_HUMAN,tr|A0A2R8YCW1|A0A2R8YCW1_HUMAN,tr|A0A2R8YDT5|A0A2R8YDT5_HUMAN,tr|A0A2R8Y645|A0A2R8Y645_HUMAN,tr|A0A2R8YF78|A0A2R8YF78_HUMAN,tr|A0A0D9SFB3|A0A0D9SFB3_HUMAN,tr|A0A2R8YFS5|A0A2R8YFS5_HUMAN,tr|A0A0D9SF53|A0A0D9SF53_HUMAN,tr|A0A087WVZ1|A0A087WVZ1_HUMAN,tr|A0A0J9YVQ7|A0A0J9YVQ7_HUMAN,tr|A0A2R8Y5G6|A0A2R8Y5G6_HUMAN,tr|A0A2R8Y7T2|A0A2R8Y7T2_HUMAN,tr|A0A0D9SG12|A0A0D9SG12_HUMAN,tr|F6S8Q4|F6S8Q4_HUMAN,tr|A0A2U3TZJ9|A0A2U3TZJ9_HUMAN,tr|A0A2R8Y4A4|A0A2R8Y4A4_HUMAN" 18 2167.9877 1.45 70990 20295 4 2167.988927 543.0042 ATP-dependent RNA helicase DDX3X OS=Homo sapiens OX=9606 GN=DDX3X PE=1 SV=3 5.33 3344.8 - 815240 - - - 0.5775 - 3.436 0.489 - 288.9 1 2 0 0.0013 17 0 0 0 1.07E+07 7.37E+06 - - - 3.9105 0.9999 221125_WJC_METTL3_EV_vs_WT_F05.20296.20296.3 0.000276 17/64 K.MLQAPESVLAEHYQDLR[166.11].R "sp|O00746|NDKM_HUMAN,tr|Q4TT34|Q4TT34_HUMAN,tr|H0Y6J0|H0Y6J0_HUMAN,tr|F2Z2X0|F2Z2X0_HUMAN,tr|A2IDC9|A2IDC9_HUMAN" 5 2008.9916 2.04 70991 20296 3 2008.997742 670.6711 "Nucleoside diphosphate kinase, mitochondrial OS=Homo sapiens OX=9606 GN=NME4 PE=1 SV=1" 4.65 3344.9 - 299075 - - - 3.0667 - 3.207 0.478 - 323.2 1 2 0 0.0062 17 0 0 0 9.99E+06 4.90E+06 - - - 6.8115 1 221125_WJC_METTL3_EV_vs_WT_F05.20309.20309.4 1.05E-09 19/102 K.WK[136.11]PPMIDNPSYQGIWK[136.11]PR[166.11].K "sp|P27824|CALX_HUMAN,tr|A0A7P0T937|A0A7P0T937_HUMAN,tr|A0A7P0T840|A0A7P0T840_HUMAN,tr|A0A7P0TB65|A0A7P0TB65_HUMAN,tr|A0A7P0TAE9|A0A7P0TAE9_HUMAN,tr|D6RGY2|D6RGY2_HUMAN,tr|A0A7P0T8G1|A0A7P0T8G1_HUMAN,tr|A0A7P0Z4D6|A0A7P0Z4D6_HUMAN,tr|A0A7P0T9L0|A0A7P0T9L0_HUMAN" 9 2238.1618 1.13 71003 20309 4 2238.166295 560.5477 Calnexin OS=Homo sapiens OX=9606 GN=CANX PE=1 SV=2 9.7 3346.6 - 1.40E+06 - - - 1.9927 - 3.558 0.579 - 367.7 1 2 0 0.0045 18 0 0 0 2.32E+07 2.05E+07 - - - 4.6992 0.9999 221125_WJC_METTL3_EV_vs_WT_F05.20311.20311.4 0.00198 13/126 R.YPDSHQLFVGNLPHDIDENELK.E "sp|Q9UN86|G3BP2_HUMAN,tr|A0A7I2V3E2|A0A7I2V3E2_HUMAN,tr|A0A7I2V647|A0A7I2V647_HUMAN,tr|A0A7I2V3Z6|A0A7I2V3Z6_HUMAN,tr|A0A7I2YQL7|A0A7I2YQL7_HUMAN,tr|A0A7I2YQD9|A0A7I2YQD9_HUMAN,tr|A0A7I2V3P9|A0A7I2V3P9_HUMAN" 7 2579.2292 3.05 71005 20311 4 2579.233368 645.8146 Ras GTPase-activating protein-binding protein 2 OS=Homo sapiens OX=9606 GN=G3BP2 PE=1 SV=2 4.42 3346.9 - 350712 - - - 1.6036 - 2.433 0.413 - 118.1 1 2 0 0.0041 22 0 0 0 2.38E+06 7.81E+05 - - - 3.1105 1 221125_WJC_METTL3_EV_vs_WT_F05.20313.20313.3 1.60E-07 24/128 R.LFGEAGPASGVGSSGGGGSGSGTGGGDAALDFK.L "sp|Q8IWZ3|ANKH1_HUMAN,tr|E9PDP5|E9PDP5_HUMAN,tr|D6RHC4|D6RHC4_HUMAN" 3 2783.2634 1.34 71007 20313 3 2783.270796 928.7618 Ankyrin repeat and KH domain-containing protein 1 OS=Homo sapiens OX=9606 GN=ANKHD1 PE=1 SV=1 4.03 3347.1 - 303727 - - - 2.6411 - 4.024 0.696 - 491.1 1 2 0 0.0074 33 0 0 0 1.64E+07 1.22E+07 - - - 9.5008 0.9999 221125_WJC_METTL3_EV_vs_WT_F05.20314.20314.3 2.18E-09 14/104 R.AIPTVNHSGTFSPQAPVPTTVPVVDVR[166.11].L "sp|Q16513|PKN2_HUMAN,tr|B1AL79|B1AL79_HUMAN" 2 2795.4845 0.99 71008 20314 3 2795.494193 932.8355 Serine\threonine-protein kinase N2 OS=Homo sapiens OX=9606 GN=PKN2 PE=1 SV=1 6.79 3347.3 - 237562 - - - 3.4498 - 2.531 0.649 - 118 1 2 0 0.0096 27 0 0 0 2.52E+06 2.54E+06 - - - 7.9094 0.9999 221125_WJC_METTL3_EV_vs_WT_F05.20317.20317.3 8.48E-06 Nov-64 K.QEVPSWLENMAYEHHYK[136.11].G "sp|O00571|DDX3X_HUMAN,sp|O15523|DDX3Y_HUMAN,tr|A0A2R8YFR4|A0A2R8YFR4_HUMAN,tr|A0A2R8YCW1|A0A2R8YCW1_HUMAN,tr|A0A2R8YDT5|A0A2R8YDT5_HUMAN,tr|A0A2R8Y645|A0A2R8Y645_HUMAN,tr|A0A2R8YF78|A0A2R8YF78_HUMAN,tr|A0A0D9SFB3|A0A0D9SFB3_HUMAN,tr|A0A2R8YFS5|A0A2R8YFS5_HUMAN,tr|A0A0D9SF53|A0A0D9SF53_HUMAN,tr|A0A087WVZ1|A0A087WVZ1_HUMAN,tr|A0A0J9YVQ7|A0A0J9YVQ7_HUMAN,tr|A0A2R8Y5G6|A0A2R8Y5G6_HUMAN,tr|A0A2R8Y7T2|A0A2R8Y7T2_HUMAN,tr|A0A0D9SG12|A0A0D9SG12_HUMAN,tr|F6S8Q4|F6S8Q4_HUMAN,tr|A0A2U3TZJ9|A0A2U3TZJ9_HUMAN,tr|A0A2R8Y4A4|A0A2R8Y4A4_HUMAN" 18 2167.9877 0.92 71011 20317 3 2167.99374 723.6698 ATP-dependent RNA helicase DDX3X OS=Homo sapiens OX=9606 GN=DDX3X PE=1 SV=3 5.33 3347.7 - 193360 - - - 2.7975 - 2.302 0.496 - 164.5 1 2 0 0.0061 17 0 0 0 1.44E+06 1.57E+06 - - - 6.1746 1 221125_WJC_METTL3_EV_vs_WT_F05.20319.20319.2 1.14E-09 30-Nov H.SDNESLGGFSIEDVQK[136.11].E "sp|Q8IWS0|PHF6_HUMAN,tr|Q5JRC6|Q5JRC6_HUMAN,tr|A0A0D9SGE8|A0A0D9SGE8_HUMAN" 3 1731.8043 0.44 71013 20319 2 1731.809354 866.9094 PHD finger protein 6 OS=Homo sapiens OX=9606 GN=PHF6 PE=1 SV=1 3.92 3347.9 - 140571 - - - 2.9334 - 2.489 0.653 - 315.6 1 1 0 0.0051 16 0 0 0 3.32E+05 7.52E+05 - - - 6.1044 1 221125_WJC_METTL3_EV_vs_WT_F05.20322.20322.3 1.98E-06 19/48 R.K[136.11]IEEIK[136.11]DFLLTAR[166.11].R "sp|P63173|RL38_HUMAN,tr|J3KT73|J3KT73_HUMAN,tr|J3QL01|J3QL01_HUMAN,tr|J3KSP2|J3KSP2_HUMAN" 4 1600.9399 0.89 71014 20322 3 1600.946338 534.6539 60S ribosomal protein L38 OS=Homo sapiens OX=9606 GN=RPL38 PE=1 SV=2 6.18 3348.4 - 1.67E+06 - - - 4.0445 - 3.222 0.622 - 474.3 1 2 1 0.0065 13 0 0 0 5.19E+08 5.83E+08 - - - 8.6451 1 221125_WJC_METTL3_EV_vs_WT_F05.20323.20323.3 1.19E-14 21/80 R.GAHGIIVVYDVTDQESFNNVK.Q "sp|P62820|RAB1A_HUMAN,tr|E7END7|E7END7_HUMAN" 2 2304.1386 1.49 71015 20323 3 2304.145908 769.0535 Ras-related protein Rab-1A OS=Homo sapiens OX=9606 GN=RAB1A PE=1 SV=3 4.54 3348.5 - 561777 - - - 3.1604 - 3.725 0.587 - 604.7 1 2 0 0.0073 21 0 0 0 8.51E+06 5.71E+06 - - - 8.2353 0.9998 221125_WJC_METTL3_EV_vs_WT_F05.20325.20325.4 1.26E-06 17/72 R.K[136.11]IEEIK[136.11]DFLLTAR[166.11].R "sp|P63173|RL38_HUMAN,tr|J3KT73|J3KT73_HUMAN,tr|J3QL01|J3QL01_HUMAN,tr|J3KSP2|J3KSP2_HUMAN" 4 1600.9399 0.85 71017 20325 4 1600.942871 401.2422 60S ribosomal protein L38 OS=Homo sapiens OX=9606 GN=RPL38 PE=1 SV=2 6.18 3348.7 - 497700 - - - 1.8789 - 2.885 0.477 - 271.3 1 2 1 0.003 13 0 0 0 1.25E+08 1.46E+08 - - - 3.7698 0.9999 221125_WJC_METTL3_EV_vs_WT_F05.20330.20330.3 0.000236 Dec-64 K.K[136.11]TESAVSQMQSVIELGR[166.11].V "sp|P41252|SYIC_HUMAN,tr|A0A804HL54|A0A804HL54_HUMAN,tr|A0A804HIV9|A0A804HIV9_HUMAN,tr|A0A804HJN6|A0A804HJN6_HUMAN,tr|A0A804HHW9|A0A804HHW9_HUMAN,tr|A0A0A0MSX9|A0A0A0MSX9_HUMAN,tr|J3KR24|J3KR24_HUMAN,tr|A0A804HJ36|A0A804HJ36_HUMAN" 8 1879.9792 0.94 71022 20330 3 1879.983079 627.667 "Isoleucine--tRNA ligase, cytoplasmic OS=Homo sapiens OX=9606 GN=IARS1 PE=1 SV=2" 6.14 3349.4 - 179858 - - - 2.0463 - 2.621 0.458 - 174.9 1 2 0 0.0038 17 0 0 0 4.32E+06 4.59E+06 - - - 6.0794 0.9999 221125_WJC_METTL3_EV_vs_WT_F05.20337.20337.4 1.00E-05 17/72 R.KIEEIKDFLLTAR.R "sp|P63173|RL38_HUMAN,tr|J3KT73|J3KT73_HUMAN,tr|J3QL01|J3QL01_HUMAN,tr|J3KSP2|J3KSP2_HUMAN" 4 1574.9032 1.09 71027 20337 4 1574.905389 394.7331 60S ribosomal protein L38 OS=Homo sapiens OX=9606 GN=RPL38 PE=1 SV=2 6.18 3350.2 - 2.39E+06 - - - 1.3944 - 2.725 0.503 - 296.7 1 2 1 0.0022 13 0 0 0 5.90E+08 5.42E+08 - - - 3.9752 0.9997 221125_WJC_METTL3_EV_vs_WT_F05.20348.20348.4 2.51E-07 13/108 K.GLEEITVHNK[136.11]DEVYQILEK[136.11].G "sp|P52732|KIF11_HUMAN,tr|A0A7I2YQY4|A0A7I2YQY4_HUMAN,tr|A0A7I2V3A9|A0A7I2V3A9_HUMAN,tr|A0A7I2V3V3|A0A7I2V3V3_HUMAN" 4 2272.1922 5.07 71036 20348 4 2272.192391 569.0553 Kinesin-like protein KIF11 OS=Homo sapiens OX=9606 GN=KIF11 PE=1 SV=2 4.57 3351.7 - 1.37E+06 - - - 0.0937 - 3.045 0.437 - 138.4 1 2 1 0.0002 19 0 0 0 4.32E+08 8.53E+07 - - - 3.4063 1 221125_WJC_METTL3_EV_vs_WT_F05.20349.20349.2 1.01E-06 19/24 R.K[136.11]IEEIK[136.11]DFLLTAR[166.11].R "sp|P63173|RL38_HUMAN,tr|J3KT73|J3KT73_HUMAN,tr|J3QL01|J3QL01_HUMAN,tr|J3KSP2|J3KSP2_HUMAN" 4 1600.9399 0.93 71037 20349 2 1600.940858 801.4772 60S ribosomal protein L38 OS=Homo sapiens OX=9606 GN=RPL38 PE=1 SV=2 6.18 3351.8 - 1.27E+06 - - - 0.6215 - 3.643 0.625 - 1346.9 1 2 1 0.001 13 0 0 0 2.62E+07 2.81E+07 - - - 6.975 1 221125_WJC_METTL3_EV_vs_WT_F05.20350.20350.2 6.35E-05 18/24 R.KIEEIKDFLLTAR.R "sp|P63173|RL38_HUMAN,tr|J3KT73|J3KT73_HUMAN,tr|J3QL01|J3QL01_HUMAN,tr|J3KSP2|J3KSP2_HUMAN" 4 1574.9032 1.19 71038 20350 2 1574.904389 788.4589 60S ribosomal protein L38 OS=Homo sapiens OX=9606 GN=RPL38 PE=1 SV=2 6.18 3351.9 - 969074 - - - 0.7594 - 3.592 0.625 - 1086.2 1 2 1 0.0012 13 0 0 0 1.23E+08 1.03E+08 - - - 6.9387 0.9999 221125_WJC_METTL3_EV_vs_WT_F05.20351.20351.3 6.66E-06 19/72 K.GLEEITVHNK[136.11]DEVYQILEK[136.11].G "sp|P52732|KIF11_HUMAN,tr|A0A7I2YQY4|A0A7I2YQY4_HUMAN,tr|A0A7I2V3A9|A0A7I2V3A9_HUMAN,tr|A0A7I2V3V3|A0A7I2V3V3_HUMAN" 4 2272.1922 5.45 71039 20351 3 2272.193616 758.4047 Kinesin-like protein KIF11 OS=Homo sapiens OX=9606 GN=KIF11 PE=1 SV=2 4.57 3352 - 943451 - - - 0.6329 - 4.089 0.518 - 439.1 1 2 1 0.0014 19 0 0 0 3.71E+08 6.82E+07 - - - 7.7747 0.9997 221125_WJC_METTL3_EV_vs_WT_F05.20353.20353.3 7.84E-06 17/48 R.K[136.11]IEEIKDFLLTAR[166.11].R "sp|P63173|RL38_HUMAN,tr|J3KT73|J3KT73_HUMAN,tr|J3QL01|J3QL01_HUMAN,tr|J3KSP2|J3KSP2_HUMAN" 4 1592.9257 - 71041 20353 3 1592.928896 531.9825 60S ribosomal protein L38 OS=Homo sapiens OX=9606 GN=RPL38 PE=1 SV=2 6.18 3352.3 - 798109 - - - 2.0296 - 2.569 0.484 - 365.1 1 2 1 0.0032 13 0 0 0 - - - - - 6.4934 0.9999 221125_WJC_METTL3_EV_vs_WT_F05.20354.20354.3 0.000119 13/56 R.KQSLGELIGTLNAAK.V sp|P60174|TPIS_HUMAN 1 1541.8777 1.38 71042 20354 3 1541.881051 514.9665 Triosephosphate isomerase OS=Homo sapiens OX=9606 GN=TPI1 PE=1 SV=4 8.59 3352.4 - 559339 - - - 2.1688 - 2.81 0.453 - 236.6 1 2 0 0.0033 15 0 0 0 1.41E+07 1.02E+07 - - - 6.2855 1 221125_WJC_METTL3_EV_vs_WT_F05.20355.20355.3 9.42E-07 Dec-64 K.KTESAVSQMQSVIELGR.V "sp|P41252|SYIC_HUMAN,tr|A0A804HL54|A0A804HL54_HUMAN,tr|A0A804HIV9|A0A804HIV9_HUMAN,tr|A0A804HJN6|A0A804HJN6_HUMAN,tr|A0A804HHW9|A0A804HHW9_HUMAN,tr|A0A0A0MSX9|A0A0A0MSX9_HUMAN,tr|J3KR24|J3KR24_HUMAN,tr|A0A804HJ36|A0A804HJ36_HUMAN" 8 1861.9568 0.94 71043 20355 3 1861.959856 621.6595 "Isoleucine--tRNA ligase, cytoplasmic OS=Homo sapiens OX=9606 GN=IARS1 PE=1 SV=2" 6.14 3352.5 - 551737 - - - 1.6617 - 2.65 0.522 - 218.1 1 2 0 0.0031 17 0 0 0 4.32E+06 4.59E+06 - - - 6.821 1 221125_WJC_METTL3_EV_vs_WT_F05.20366.20366.3 2.06E-13 24/76 K.HQVMINQFVLTAGC[160.03]AADQAK.Q "sp|Q8TB05|UBAD1_HUMAN,tr|K7EM88|K7EM88_HUMAN,tr|K7EQ49|K7EQ49_HUMAN,tr|K7EKR5|K7EKR5_HUMAN,tr|K7EM52|K7EM52_HUMAN" 5 2201.0721 0.4 71052 20366 3 2201.071791 734.698 UBA-like domain-containing protein 1 OS=Homo sapiens OX=9606 GN=UBALD1 PE=1 SV=1 6.73 3353.9 - 1.10E+06 - - - -0.1599 - 5.07 0.694 - 875.4 1 2 0 -0.0004 20 0 0 0 8.30E+06 2.05E+07 - - - 10.2156 0.9919 221125_WJC_METTL3_EV_vs_WT_F05.20370.20370.2 1.5 12-Jul K.K[136.11]IEEYK[136.11]R[166.11].E "sp|P23760|PAX3_HUMAN,sp|Q96P16|RPR1A_HUMAN,sp|P23759|PAX7_HUMAN" 3 990.5709 0.01 71056 20370 2 990.571034 496.2927 Paired box protein Pax-3 OS=Homo sapiens OX=9606 GN=PAX3 PE=1 SV=2 8.5 3354.4 - 235188 - - - 0.1847 - 1.457 0.073 - 159.6 1 2 0 0.0002 7 0 0 0 2.43E+04 2.75E+06 - - - 0.7727 1 221125_WJC_METTL3_EV_vs_WT_F05.20374.20374.3 1.97E-15 19/128 R.LFGEAGPASGVGSSGGGGSGSGTGGGDAALDFK[136.11].L "sp|Q8IWZ3|ANKH1_HUMAN,tr|E9PDP5|E9PDP5_HUMAN,tr|D6RHC4|D6RHC4_HUMAN" 3 2791.2776 1.34 71058 20374 3 2791.276641 931.4332 Ankyrin repeat and KH domain-containing protein 1 OS=Homo sapiens OX=9606 GN=ANKHD1 PE=1 SV=1 4.03 3354.9 - 870054 - - - -0.3597 - 3.747 0.729 - 263.5 1 2 0 -0.001 33 0 0 0 1.64E+07 1.22E+07 - - - 9.7064 1 221125_WJC_METTL3_EV_vs_WT_F05.20375.20375.3 1.62E-12 18/72 K.K[136.11]EDGTFYEFGEDIPEAPER[166.11].L sp|O43776|SYNC_HUMAN 1 2246.0134 2.1 71059 20375 3 2246.010215 749.6784 "Asparagine--tRNA ligase, cytoplasmic OS=Homo sapiens OX=9606 GN=NARS1 PE=1 SV=1" 4 3355 - 903253 - - - -1.431 - 3.479 0.603 - 286.3 1 2 0 -0.0032 19 0 0 0 9.38E+06 4.47E+06 - - - 8.325 1 221125_WJC_METTL3_EV_vs_WT_F05.20376.20376.3 0.00316 18/68 K.GQVC[160.03]LPVISAENWKPATK.T "sp|A0A1B0GUS4|UB2L5_HUMAN,sp|P68036|UB2L3_HUMAN" 2 1997.0404 3.51 71060 20376 3 1997.037979 666.6874 Ubiquitin-conjugating enzyme E2 L5 OS=Homo sapiens OX=9606 GN=UBE2L5 PE=2 SV=1 8.2 3355.2 - 558242 - - - -1.2283 - 3.129 0.531 - 324.8 1 2 0 -0.0025 18 0 0 0 7.40E+07 2.11E+07 - - - 7.2999 0.7721 221125_WJC_METTL3_EV_vs_WT_F05.20380.20380.3 4.75E-07 Nov-76 L.AISTPDAPATQDGVESLLQK[136.11].F "sp|Q86U44|MTA70_HUMAN,tr|B4E349|B4E349_HUMAN,tr|F5H6D8|F5H6D8_HUMAN,tr|H0YFV6|H0YFV6_HUMAN,tr|B4DTN4|B4DTN4_HUMAN" 5 2048.0517 0.02 71064 20380 3 2049.049812 683.6912 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 4.03 3355.7 - 393728 - - - 487.3397 - 2.378 0.532 - 108.6 1 1 0 0.9981 20 0 0 0 4.57E+04 2.30E+06 - - - 6.2964 0.9999 221125_WJC_METTL3_EV_vs_WT_F05.20383.20383.4 4.70E-07 15/108 K.GLEEITVHNKDEVYQILEK.G "sp|P52732|KIF11_HUMAN,tr|A0A7I2YQY4|A0A7I2YQY4_HUMAN,tr|A0A7I2V3A9|A0A7I2V3A9_HUMAN,tr|A0A7I2V3V3|A0A7I2V3V3_HUMAN" 4 2256.1638 5.07 71066 20383 4 2256.162253 565.0482 Kinesin-like protein KIF11 OS=Homo sapiens OX=9606 GN=KIF11 PE=1 SV=2 4.57 3356.1 - 2.32E+07 - - - -0.6759 - 3.343 0.5 - 221.1 1 2 1 -0.0015 19 0 0 0 4.32E+08 8.53E+07 - - - 3.9858 1 221125_WJC_METTL3_EV_vs_WT_F05.20384.20384.4 1.35E-06 17/102 K.WKPPMIDNPSYQGIWKPR.K "sp|P27824|CALX_HUMAN,tr|A0A7P0T937|A0A7P0T937_HUMAN,tr|A0A7P0T840|A0A7P0T840_HUMAN,tr|A0A7P0TB65|A0A7P0TB65_HUMAN,tr|A0A7P0TAE9|A0A7P0TAE9_HUMAN,tr|D6RGY2|D6RGY2_HUMAN,tr|A0A7P0T8G1|A0A7P0T8G1_HUMAN,tr|A0A7P0Z4D6|A0A7P0Z4D6_HUMAN,tr|A0A7P0T9L0|A0A7P0T9L0_HUMAN" 9 2212.1252 1.15 71067 20384 4 2212.126245 554.0386 Calnexin OS=Homo sapiens OX=9606 GN=CANX PE=1 SV=2 9.7 3356.2 - 484182 - - - 0.4882 - 3.087 0.545 - 269.2 1 2 0 0.0011 18 0 0 0 2.32E+07 2.02E+07 - - - 4.3555 1 221125_WJC_METTL3_EV_vs_WT_F05.20387.20387.3 2.72E-15 27/112 K.VIDPVTGKPC[160.03]AGTTYLESPLSSETTQLSK.N "sp|Q9Y2R5|RT17_HUMAN,tr|I3L0E3|I3L0E3_HUMAN,tr|E9PE17|E9PE17_HUMAN" 3 3078.5431 0.98 71070 20387 3 3078.545152 1027.1883 "28S ribosomal protein S17, mitochondrial OS=Homo sapiens OX=9606 GN=MRPS17 PE=1 SV=1" 4.68 3356.6 - 934610 - - - 0.6672 - 5.155 0.713 - 587.2 1 2 0 0.0021 29 0 0 0 7.64E+06 7.76E+06 - - - 10.2616 1 221125_WJC_METTL3_EV_vs_WT_F05.20389.20389.3 9.75E-07 27/116 R.C[160.03]LQLGSPGPGPVAAGPGPASVSGLAAGSGR[166.11].D sp|Q8IYS2|K2013_HUMAN 1 2654.3474 2.94 71072 20389 3 2654.35452 885.7897 Uncharacterized protein KIAA2013 OS=Homo sapiens OX=9606 GN=KIAA2013 PE=1 SV=1 8.25 3356.8 - 383296 - - - 2.6809 - 4.384 0.669 - 708.7 1 2 0 0.0071 30 0 0 0 7.79E+06 2.65E+06 - - - 9.397 0.9999 221125_WJC_METTL3_EV_vs_WT_F05.20397.20397.4 3.78E-07 17/120 K.DGNVLLHEMQIQHPTASLIAK[136.11].V sp|P40227|TCPZ_HUMAN 1 2322.2246 0.42 71078 20397 4 2322.219478 581.5634 T-complex protein 1 subunit zeta OS=Homo sapiens OX=9606 GN=CCT6A PE=1 SV=3 5.99 3357.9 - 2.01E+06 - - - -2.1845 - 2.783 0.484 - 152.9 1 2 0 -0.0051 21 0 0 0 1.30E+08 3.11E+08 - - - 3.7757 1 221125_WJC_METTL3_EV_vs_WT_F05.20399.20399.3 5.58E-11 22/92 R.SLYQSAGVAPESFEYIEAHGTGTK[136.11].V "sp|P49327|FAS_HUMAN,tr|A0A0U1RQF0|A0A0U1RQF0_HUMAN" 2 2549.2165 0.8 71080 20399 3 2549.216492 850.7461 Fatty acid synthase OS=Homo sapiens OX=9606 GN=FASN PE=1 SV=3 4.75 3358.1 - 1.20E+06 - - - -0.022 - 3.705 0.622 - 609.1 1 2 0 -0.0001 24 0 0 0 2.19E+07 2.72E+07 - - - 8.5165 1 221125_WJC_METTL3_EV_vs_WT_F05.20400.20400.3 5.15E-10 19/112 K.VIDPVTGK[136.11]PC[160.03]AGTTYLESPLSSETTQLSK[136.11].N "sp|Q9Y2R5|RT17_HUMAN,tr|I3L0E3|I3L0E3_HUMAN,tr|E9PE17|E9PE17_HUMAN" 3 3094.5715 0.98 71081 20400 3 3094.567963 1032.5311 "28S ribosomal protein S17, mitochondrial OS=Homo sapiens OX=9606 GN=MRPS17 PE=1 SV=1" 4.68 3358.2 - 759851 - - - -1.1423 - 3.765 0.65 - 284.7 1 2 0 -0.0035 29 0 0 0 7.64E+06 7.76E+06 - - - 8.8359 1 221125_WJC_METTL3_EV_vs_WT_F05.20401.20401.3 6.32E-11 26/116 R.C[160.03]LQLGSPGPGPVAAGPGPASVSGLAAGSGR.D sp|Q8IYS2|K2013_HUMAN 1 2644.3391 2.92 71082 20401 3 2644.339684 882.4537 Uncharacterized protein KIAA2013 OS=Homo sapiens OX=9606 GN=KIAA2013 PE=1 SV=1 8.25 3358.3 - 716192 - - - 0.208 - 4.996 0.643 - 656.2 1 2 0 0.0006 30 0 0 0 7.73E+06 2.65E+06 - - - 9.4096 0.9996 221125_WJC_METTL3_EV_vs_WT_F05.20403.20403.4 0.0152 11/138 K.QLIADVTLDPETAHPNLVLSEDR[166.11]K[136.11].S "sp|Q9HCM9|TRI39_HUMAN,tr|A0A0G2JKY0|A0A0G2JKY0_HUMAN,tr|A0A096LP39|A0A096LP39_HUMAN,tr|A0A140TA46|A0A140TA46_HUMAN" 4 2691.4198 7.13 71084 20403 4 2691.423581 673.8622 E3 ubiquitin-protein ligase TRIM39 OS=Homo sapiens OX=9606 GN=TRIM39 PE=1 SV=2 4.43 3358.6 - 281584 - - - 1.3937 - 2.283 0.341 - 53.7 1 2 0 0.0038 24 0 0 0 1.30E+07 1.82E+06 - - - 2.458 0.9997 221125_WJC_METTL3_EV_vs_WT_F05.20404.20404.3 2.46E-06 Nov-56 K.DRDPEAQFEMPYVVR.L "sp|O14744|ANM5_HUMAN,tr|H0YJD3|H0YJD3_HUMAN,tr|H7BZ44|H7BZ44_HUMAN" 3 1850.8621 3.36 71085 20404 3 1850.857962 617.9613 Protein arginine N-methyltransferase 5 OS=Homo sapiens OX=9606 GN=PRMT5 PE=1 SV=4 4.32 3358.7 - 234443 - - - -2.2535 - 2.349 0.514 - 164.6 1 2 1 -0.0042 15 0 0 0 1.22E+07 3.63E+06 - - - 6.4978 0.9999 221125_WJC_METTL3_EV_vs_WT_F05.20405.20405.3 4.85E-05 Sep-48 R.LVNLQHLDLLNNK[136.11].L sp|Q96AG4|LRC59_HUMAN 1 1540.8817 1.1 71086 20405 3 1540.880556 514.6345 Leucine-rich repeat-containing protein 59 OS=Homo sapiens OX=9606 GN=LRRC59 PE=1 SV=1 6.74 3358.9 - 234016 - - - -0.7275 - 1.785 0.436 - 75.4 1 2 0 -0.0011 13 0 0 0 2.48E+06 2.26E+06 - - - 4.9716 0.9996 221125_WJC_METTL3_EV_vs_WT_F05.20406.20406.4 0.00827 7/108 R.FLLVYLHGDDHQDSDEFC[160.03]R.N sp|Q96CS3|FAF2_HUMAN 1 2365.0433 1.64 71087 20406 4 2365.040594 592.2681 FAS-associated factor 2 OS=Homo sapiens OX=9606 GN=FAF2 PE=1 SV=2 4.34 3359 - 232665 - - - -1.1636 - 1.541 0.354 - 22.4 1 2 0 -0.0028 19 0 0 0 1.37E+06 8.36E+05 - - - 2.4527 0.8454 221125_WJC_METTL3_EV_vs_WT_F05.20408.20408.3 0.373 Jul-76 K.EQVTNVGGAVVTGVTAVAQK.T "sp|P37840|SYUA_HUMAN,tr|A0A669KB41|A0A669KB41_HUMAN,tr|A0A669KBH5|A0A669KBH5_HUMAN,tr|H6UYS7|H6UYS7_HUMAN,tr|E7EPV7|E7EPV7_HUMAN" 5 1927.0375 2.01 71088 20408 3 1927.036773 643.3531 Alpha-synuclein OS=Homo sapiens OX=9606 GN=SNCA PE=1 SV=1 6.1 3359.2 - 187589 - - - -0.3539 - 1.398 0.074 - 41.6 1 2 0 -0.0007 20 0 0 0 2.49E+06 1.24E+06 - - - 0.1777 1 221125_WJC_METTL3_EV_vs_WT_F05.20410.20410.3 1.40E-05 21/92 R.SLYQSAGVAPESFEYIEAHGTGTK.V "sp|P49327|FAS_HUMAN,tr|A0A0U1RQF0|A0A0U1RQF0_HUMAN" 2 2541.2023 0.8 71089 20410 3 2541.201715 848.0747 Fatty acid synthase OS=Homo sapiens OX=9606 GN=FASN PE=1 SV=3 4.75 3359.4 - 1.13E+06 - - - -0.2491 - 3.896 0.588 - 615.5 1 2 0 -0.0006 24 0 0 0 2.19E+07 2.72E+07 - - - 8.2541 1 221125_WJC_METTL3_EV_vs_WT_F05.20411.20411.2 3.04E-08 15/36 A.ISTPDAPATQDGVESLLQK[136.11].F "sp|Q86U44|MTA70_HUMAN,tr|B4E349|B4E349_HUMAN,tr|F5H6D8|F5H6D8_HUMAN,tr|H0YFV6|H0YFV6_HUMAN,tr|B4DTN4|B4DTN4_HUMAN" 5 1977.0146 0.01 71090 20411 2 1977.013466 989.5146 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 4.03 3359.6 - 567516 - - - -0.5741 - 3.027 0.626 - 543.8 1 1 0 -0.0011 19 0 0 0 5.30E+04 9.68E+06 - - - 6.3873 1 221125_WJC_METTL3_EV_vs_WT_F05.20412.20412.3 0.00163 17/64 K.DKPNPQLIYDDEIPSLK.L "sp|Q9Y2L1|RRP44_HUMAN,tr|G3V1J5|G3V1J5_HUMAN" 2 1984.0153 1.71 71091 20412 3 1984.018007 662.3457 Exosome complex exonuclease RRP44 OS=Homo sapiens OX=9606 GN=DIS3 PE=1 SV=2 4.23 3359.6 - 1.21E+06 - - - 1.3528 - 3.058 0.471 - 307.3 1 2 0 0.0027 17 0 0 0 1.30E+08 7.65E+07 - - - 6.6142 0.9999 221125_WJC_METTL3_EV_vs_WT_F05.20413.20413.3 1.72E-05 Nov-60 K.EDSHPFDLGLYNEAVK.L "sp|P35244|RFA3_HUMAN,tr|B5MC59|B5MC59_HUMAN" 2 1832.8581 1.37 71092 20413 3 1832.855342 611.96 Replication protein A 14 kDa subunit OS=Homo sapiens OX=9606 GN=RPA3 PE=1 SV=1 4.31 3359.8 - 619817 - - - -1.5015 - 1.966 0.489 - 108.4 1 2 0 -0.0028 16 0 0 0 1.51E+07 1.11E+07 - - - 5.7256 0.9854 221125_WJC_METTL3_EV_vs_WT_F05.20419.20419.2 2 12-Jul K.KIEEYKR[166.11].E "sp|P23760|PAX3_HUMAN,sp|Q96P16|RPR1A_HUMAN,sp|P23759|PAX7_HUMAN" 3 974.5425 - 71098 20419 2 974.544837 488.2785 Paired box protein Pax-3 OS=Homo sapiens OX=9606 GN=PAX3 PE=1 SV=2 8.5 3360.6 - 216089 - - - 2.4483 - 1.445 0.127 - 170.2 1 2 0 0.0024 7 0 0 0 - - - - - 1.1446 0.9999 221125_WJC_METTL3_EV_vs_WT_F05.20422.20422.3 3.43E-05 16/64 K.DK[136.11]PNPQLIYDDEIPSLK[136.11].L "sp|Q9Y2L1|RRP44_HUMAN,tr|G3V1J5|G3V1J5_HUMAN" 2 2000.0437 1.71 71099 20422 3 2000.040127 667.6885 Exosome complex exonuclease RRP44 OS=Homo sapiens OX=9606 GN=DIS3 PE=1 SV=2 4.23 3361 - 1.35E+06 - - - -1.798 - 3.166 0.404 - 255.4 1 2 0 -0.0036 17 0 0 0 1.30E+08 7.63E+07 - - - 5.9547 1 221125_WJC_METTL3_EV_vs_WT_F05.20423.20423.3 5.88E-15 22/80 K.DGNVLLHEMQIQHPTASLIAK.V sp|P40227|TCPZ_HUMAN 1 2314.2104 0.36 71100 20423 3 2314.214193 772.4107 T-complex protein 1 subunit zeta OS=Homo sapiens OX=9606 GN=CCT6A PE=1 SV=3 5.99 3361.1 - 654661 - - - 1.6602 - 4.244 0.746 - 553.4 1 2 0 0.0038 21 0 0 0 3.27E+07 9.08E+07 - - - 10.3216 1 221125_WJC_METTL3_EV_vs_WT_F05.20424.20424.3 1.02E-14 30/80 K.DGNVLLHEMQIQHPTASLIAK[136.11].V sp|P40227|TCPZ_HUMAN 1 2322.2246 0.36 71101 20424 3 2322.221759 775.0821 T-complex protein 1 subunit zeta OS=Homo sapiens OX=9606 GN=CCT6A PE=1 SV=3 5.99 3361.2 - 1.52E+06 - - - -1.2023 - 5.187 0.719 - 1175.5 1 2 0 -0.0028 21 0 0 0 3.27E+07 9.08E+07 - - - 10.5019 1 221125_WJC_METTL3_EV_vs_WT_F05.20425.20425.3 5.39E-09 16/116 R.GAAAAATGQPGTAPAGTPGAPPLAGMAIVK[136.11].E "sp|Q13263|TIF1B_HUMAN,tr|M0R0K9|M0R0K9_HUMAN" 2 2579.3621 0.77 71102 20425 3 2579.357199 860.7946 Transcription intermediary factor 1-beta OS=Homo sapiens OX=9606 GN=TRIM28 PE=1 SV=5 8.75 3361.4 - 579699 - - - -1.9028 - 3.07 0.596 - 152.6 1 2 0 -0.0049 30 0 0 0 1.33E+07 1.73E+07 - - - 7.764 0.9999 221125_WJC_METTL3_EV_vs_WT_F05.20428.20428.3 7.20E-08 21/48 R.KIEEIKDFLLTAR.R "sp|P63173|RL38_HUMAN,tr|J3KT73|J3KT73_HUMAN,tr|J3QL01|J3QL01_HUMAN,tr|J3KSP2|J3KSP2_HUMAN" 4 1574.9032 1.16 71104 20428 3 1574.903078 525.975 60S ribosomal protein L38 OS=Homo sapiens OX=9606 GN=RPL38 PE=1 SV=2 6.18 3361.7 - 7.18E+07 - - - -0.073 - 2.916 0.558 - 705.9 1 2 1 -0.0001 13 0 0 0 2.48E+09 2.15E+09 - - - 7.6628 1 221125_WJC_METTL3_EV_vs_WT_F05.20431.20431.3 1.55E-10 19/116 R.GAAAAATGQPGTAPAGTPGAPPLAGMAIVK.E "sp|Q13263|TIF1B_HUMAN,tr|M0R0K9|M0R0K9_HUMAN" 2 2571.3479 0.77 71106 20431 3 2571.342009 858.1232 Transcription intermediary factor 1-beta OS=Homo sapiens OX=9606 GN=TRIM28 PE=1 SV=5 8.75 3362.1 - 543569 - - - -2.2937 - 3.056 0.631 - 239.8 1 2 0 -0.0059 30 0 0 0 1.33E+07 1.73E+07 - - - 8.1434 0.9925 221125_WJC_METTL3_EV_vs_WT_F05.20432.20432.3 6.91E-05 Nov-72 A.ISTPDAPATQDGVESLLQK[136.11].F "sp|Q86U44|MTA70_HUMAN,tr|B4E349|B4E349_HUMAN,tr|F5H6D8|F5H6D8_HUMAN,tr|H0YFV6|H0YFV6_HUMAN,tr|B4DTN4|B4DTN4_HUMAN" 5 1977.0146 0.01 71107 20432 3 1977.013724 660.0121 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 4.03 3362.1 - 931912 - - - -0.4436 - 2.32 0.44 - 147.1 1 1 0 -0.0009 19 0 0 0 1.97E+05 1.83E+07 - - - 5.5129 0.9999 221125_WJC_METTL3_EV_vs_WT_F05.20433.20433.3 1.27E-07 Dec-60 K.EDSHPFDLGLYNEAVK[136.11].L "sp|P35244|RFA3_HUMAN,tr|B5MC59|B5MC59_HUMAN" 2 1840.8723 1.37 71108 20433 3 1840.866189 614.6314 Replication protein A 14 kDa subunit OS=Homo sapiens OX=9606 GN=RPA3 PE=1 SV=1 4.31 3362.3 - 664141 - - - -3.3164 - 2.199 0.542 - 181.4 1 2 0 -0.0061 16 0 0 0 1.51E+07 1.11E+07 - - - 6.603 0.9995 221125_WJC_METTL3_EV_vs_WT_F05.20435.20435.3 2.11E-07 14/60 K.TDLEKDIISDTSGDFR.K "sp|P07355|ANXA2_HUMAN,sp|A6NMY6|AXA2L_HUMAN,tr|H0YL33|H0YL33_HUMAN,tr|H0YMU9|H0YMU9_HUMAN,tr|H0YNA0|H0YNA0_HUMAN,tr|H0YM50|H0YM50_HUMAN,tr|H0YMD0|H0YMD0_HUMAN,tr|H0YMW4|H0YMW4_HUMAN,tr|H0YN42|H0YN42_HUMAN,tr|H0YN28|H0YN28_HUMAN,tr|H0YNP5|H0YNP5_HUMAN,tr|H0YNB8|H0YNB8_HUMAN,tr|H0YKS4|H0YKS4_HUMAN" 13 1810.8585 8.62 71110 20435 3 1810.856956 604.6268 Annexin A2 OS=Homo sapiens OX=9606 GN=ANXA2 PE=1 SV=2 4.04 3362.5 - 520375 - - - -0.846 - 2.982 0.345 - 264.6 1 2 1 -0.0015 16 0 0 0 3.34E+07 3.88E+06 - - - 5.1894 0.9963 221125_WJC_METTL3_EV_vs_WT_F05.20440.20440.3 5.01E-06 13/60 K.LHEEEIQELQAQIQEQ.H "sp|P08670|VIME_HUMAN,tr|B0YJC5|B0YJC5_HUMAN,tr|B0YJC4|B0YJC4_HUMAN" 3 1963.9487 - 71113 20440 3 1963.950702 655.6568 Vimentin OS=Homo sapiens OX=9606 GN=VIM PE=1 SV=4 3.98 3363.1 - 441696 - - - 1.0194 - 2.848 0.469 - 249.6 1 1 0 0.002 16 0 0 0 - - - - - 6.4538 0.9822 221125_WJC_METTL3_EV_vs_WT_F05.20441.20441.3 3.04E-06 14/64 L.EEITVHNKDEVYQILEK.G "sp|P52732|KIF11_HUMAN,tr|A0A7I2YQY4|A0A7I2YQY4_HUMAN,tr|A0A7I2V3A9|A0A7I2V3A9_HUMAN,tr|A0A7I2V3V3|A0A7I2V3V3_HUMAN" 4 2086.0583 13.11 71114 20441 3 2086.06118 696.36 Kinesin-like protein KIF11 OS=Homo sapiens OX=9606 GN=KIF11 PE=1 SV=2 4.57 3363.3 - 373571 - - - 1.4046 - 2.92 0.482 - 265.8 1 1 1 0.0029 17 0 0 0 9.86E+06 7.52E+05 - - - 6.6202 1 221125_WJC_METTL3_EV_vs_WT_F05.20445.20445.3 4.30E-07 13/56 K.KPLFHGDSEIDQLFR.L "sp|P06493|CDK1_HUMAN,tr|A0A024QZP7|A0A024QZP7_HUMAN,tr|A0A087WZZ9|A0A087WZZ9_HUMAN" 3 1800.9159 0.98 71116 20445 3 1800.915059 601.3126 Cyclin-dependent kinase 1 OS=Homo sapiens OX=9606 GN=CDK1 PE=1 SV=3 5.38 3363.8 - 225406 - - - -0.4575 - 2.916 0.565 - 216.3 1 2 0 -0.0008 15 0 0 0 9.91E+06 1.01E+07 - - - 7.6315 1 221125_WJC_METTL3_EV_vs_WT_F05.20449.20449.3 3.42E-07 16/84 R.EPFDLGEPEQSNGGFPC[160.03]TTAPK.L sp|Q99961|SH3G1_HUMAN 1 2377.0532 2.09 71118 20449 3 2377.051725 793.3584 Endophilin-A2 OS=Homo sapiens OX=9606 GN=SH3GL1 PE=1 SV=1 4 3364.3 - 469718 - - - -0.6382 - 2.82 0.619 - 231.7 1 2 0 -0.0015 22 0 0 0 1.54E+07 7.37E+06 - - - 7.8987 1 221125_WJC_METTL3_EV_vs_WT_F05.20453.20453.2 2.53E-09 30-Dec K.LHEEEIQELQAQIQEQ.H "sp|P08670|VIME_HUMAN,tr|B0YJC5|B0YJC5_HUMAN,tr|B0YJC4|B0YJC4_HUMAN" 3 1963.9487 - 71120 20453 2 1963.95004 982.9816 Vimentin OS=Homo sapiens OX=9606 GN=VIM PE=1 SV=4 3.98 3364.8 - 387051 - - - 0.6823 - 2.648 0.594 - 413.1 1 1 0 0.0013 16 0 0 0 - - - - - 5.822 1 221125_WJC_METTL3_EV_vs_WT_F05.20455.20455.4 1.16E-13 21/120 K.DGNVLLHEMQIQHPTASLIAK.V sp|P40227|TCPZ_HUMAN 1 2314.2104 0.42 71121 20455 4 2314.209871 579.5599 T-complex protein 1 subunit zeta OS=Homo sapiens OX=9606 GN=CCT6A PE=1 SV=3 5.99 3365.1 - 4.99E+06 - - - -0.2074 - 4.08 0.667 - 355.9 1 2 0 -0.0005 21 0 0 0 1.31E+08 3.11E+08 - - - 5.4963 1 221125_WJC_METTL3_EV_vs_WT_F05.20456.20456.4 1.56E-07 26/162 R.ASLPQAATFGELSGPLKPGSPYRPPVPR.A "sp|Q14687|GSE1_HUMAN,tr|H0Y613|H0Y613_HUMAN" 2 2889.5501 5.53 71122 20456 4 2889.544397 723.3948 Genetic suppressor element 1 OS=Homo sapiens OX=9606 GN=GSE1 PE=1 SV=3 9.99 3365.2 - 535122 - - - -1.9782 - 3.84 0.592 - 326.2 1 2 0 -0.0057 28 0 0 0 8.75E+06 1.58E+06 - - - 4.7949 1 221125_WJC_METTL3_EV_vs_WT_F05.20457.20457.3 5.88E-06 13/56 K.K[136.11]PLFHGDSEIDQLFR[166.11].L "sp|P06493|CDK1_HUMAN,tr|A0A024QZP7|A0A024QZP7_HUMAN,tr|A0A087WZZ9|A0A087WZZ9_HUMAN" 3 1818.9384 0.98 71123 20457 3 1818.937737 607.3201 Cyclin-dependent kinase 1 OS=Homo sapiens OX=9606 GN=CDK1 PE=1 SV=3 5.38 3365.3 - 356170 - - - -0.3387 - 2.81 0.556 - 222.8 1 2 0 -0.0006 15 0 0 0 9.94E+06 1.02E+07 - - - 7.4346 0.9986 221125_WJC_METTL3_EV_vs_WT_F05.20458.20458.2 0.0131 13/30 K.TDLEKDIISDTSGDFR.K "sp|P07355|ANXA2_HUMAN,sp|A6NMY6|AXA2L_HUMAN,tr|H0YL33|H0YL33_HUMAN,tr|H0YMU9|H0YMU9_HUMAN,tr|H0YNA0|H0YNA0_HUMAN,tr|H0YM50|H0YM50_HUMAN,tr|H0YMD0|H0YMD0_HUMAN,tr|H0YMW4|H0YMW4_HUMAN,tr|H0YN42|H0YN42_HUMAN,tr|H0YN28|H0YN28_HUMAN,tr|H0YNP5|H0YNP5_HUMAN,tr|H0YNB8|H0YNB8_HUMAN,tr|H0YKS4|H0YKS4_HUMAN" 13 1810.8585 999 71124 20458 2 1810.858895 906.4365 Annexin A2 OS=Homo sapiens OX=9606 GN=ANXA2 PE=1 SV=2 4.04 3365.4 - 161811 - - - 0.2248 - 2.41 0.496 - 482.4 1 2 1 0.0004 16 0 0 0 1.11E+06 0.00E+00 - - - 4.8669 1 221125_WJC_METTL3_EV_vs_WT_F05.20463.20463.4 2.55E-05 Dec-84 K.K[136.11]PLFHGDSEIDQLFR[166.11].L "sp|P06493|CDK1_HUMAN,tr|A0A024QZP7|A0A024QZP7_HUMAN,tr|A0A087WZZ9|A0A087WZZ9_HUMAN" 3 1818.9384 1.1 71127 20463 4 1818.941233 455.7419 Cyclin-dependent kinase 1 OS=Homo sapiens OX=9606 GN=CDK1 PE=1 SV=3 5.38 3366.1 - 162739 - - - 1.5833 - 2.474 0.516 - 138.2 1 2 0 0.0029 15 0 0 0 4.35E+06 3.95E+06 - - - 4.0406 0.9997 221125_WJC_METTL3_EV_vs_WT_F05.20467.20467.4 1.60E-05 10/102 R.VNFDDYTVNLGGLKDHIK.E "sp|Q06210|GFPT1_HUMAN,tr|A0A6I8PRN4|A0A6I8PRN4_HUMAN,tr|A0A6I8PTT9|A0A6I8PTT9_HUMAN" 3 2047.0375 1.12 71131 20467 4 2047.039386 512.7666 Glutamine--fructose-6-phosphate aminotransferase [isomerizing] 1 OS=Homo sapiens OX=9606 GN=GFPT1 PE=1 SV=3 5.3 3366.6 - 218282 - - - 0.9433 - 2.108 0.44 - 91.6 1 2 1 0.0019 18 0 0 0 1.30E+07 1.16E+07 - - - 3.3107 0.9999 221125_WJC_METTL3_EV_vs_WT_F05.20479.20479.4 1.50E-06 14/102 R.VNFDDYTVNLGGLK[136.11]DHIK[136.11].E "sp|Q06210|GFPT1_HUMAN,tr|A0A6I8PRN4|A0A6I8PRN4_HUMAN,tr|A0A6I8PTT9|A0A6I8PTT9_HUMAN" 3 2063.0659 1.12 71139 20479 4 2063.064429 516.7737 Glutamine--fructose-6-phosphate aminotransferase [isomerizing] 1 OS=Homo sapiens OX=9606 GN=GFPT1 PE=1 SV=3 5.3 3368.2 - 421142 - - - -0.6912 - 3.023 0.55 - 197.7 1 2 1 -0.0014 18 0 0 0 1.30E+07 1.16E+07 - - - 4.3918 0.9998 221125_WJC_METTL3_EV_vs_WT_F05.20488.20488.3 1.46E-07 Dec-80 R.AAC[160.03]QEAQVFGNQLIPPNAQVK[136.11].K "sp|Q53H12|AGK_HUMAN,tr|E9PC15|E9PC15_HUMAN,tr|A0A3B3IS09|A0A3B3IS09_HUMAN,tr|A0A3B3ITX7|A0A3B3ITX7_HUMAN,tr|E9PG39|E9PG39_HUMAN,tr|A0A3B3ISZ0|A0A3B3ISZ0_HUMAN" 6 2290.162 1.32 71146 20488 3 2290.158272 764.3946 "Acylglycerol kinase, mitochondrial OS=Homo sapiens OX=9606 GN=AGK PE=1 SV=2" 6.04 3369.4 - 334478 - - - -1.6064 - 2.281 0.395 - 86.4 1 2 0 -0.0037 21 0 0 0 1.55E+07 1.17E+07 - - - 4.9198 0.9985 221125_WJC_METTL3_EV_vs_WT_F05.20491.20491.4 0.00989 Aug-84 K.KPLFHGDSEIDQLFR.L "sp|P06493|CDK1_HUMAN,tr|A0A024QZP7|A0A024QZP7_HUMAN,tr|A0A087WZZ9|A0A087WZZ9_HUMAN" 3 1800.9159 1.1 71149 20491 4 1800.919631 451.2362 Cyclin-dependent kinase 1 OS=Homo sapiens OX=9606 GN=CDK1 PE=1 SV=3 5.38 3369.8 - 115094 - - - 2.0812 - 1.804 0.304 - 63.5 1 2 0 0.0037 15 0 0 0 4.33E+06 3.95E+06 - - - 2.0821 1 221125_WJC_METTL3_EV_vs_WT_F05.20496.20496.4 1.44E-06 17/84 K.SYEALVQHVIEDHER[166.11].L "sp|Q9H2P0|ADNP_HUMAN,tr|A0A2R8Y6X0|A0A2R8Y6X0_HUMAN,tr|A0A669KBJ7|A0A669KBJ7_HUMAN" 3 1833.8885 1.01 71152 20496 4 1833.888763 459.4794 Activity-dependent neuroprotector homeobox protein OS=Homo sapiens OX=9606 GN=ADNP PE=1 SV=1 4.8 3370.5 - 726544 - - - 0.1456 - 2.603 0.553 - 128.5 1 2 0 0.0003 15 0 0 0 9.05E+06 8.95E+06 - - - 4.3815 0.9998 221125_WJC_METTL3_EV_vs_WT_F05.20497.20497.4 0.000618 Nov-84 K.SYEALVQHVIEDHER.L "sp|Q9H2P0|ADNP_HUMAN,tr|A0A2R8Y6X0|A0A2R8Y6X0_HUMAN,tr|A0A669KBJ7|A0A669KBJ7_HUMAN" 3 1823.8802 1.01 71153 20497 4 1823.880733 456.9773 Activity-dependent neuroprotector homeobox protein OS=Homo sapiens OX=9606 GN=ADNP PE=1 SV=1 4.8 3370.6 - 529976 - - - 0.278 - 1.898 0.388 - 50.3 1 2 0 0.0005 15 0 0 0 9.05E+06 8.95E+06 - - - 2.8323 1 221125_WJC_METTL3_EV_vs_WT_F05.20506.20506.3 1.39E-08 17/56 K.SYEALVQHVIEDHER.L "sp|Q9H2P0|ADNP_HUMAN,tr|A0A2R8Y6X0|A0A2R8Y6X0_HUMAN,tr|A0A669KBJ7|A0A669KBJ7_HUMAN" 3 1823.8802 0.97 71159 20506 3 1823.88202 608.9674 Activity-dependent neuroprotector homeobox protein OS=Homo sapiens OX=9606 GN=ADNP PE=1 SV=1 4.8 3371.8 - 417978 - - - 0.9836 - 3.1 0.609 - 241.6 1 2 0 0.0018 15 0 0 0 5.43E+06 5.58E+06 - - - 8.2815 0.9986 221125_WJC_METTL3_EV_vs_WT_F05.20509.20509.3 0.002 Oct-64 R.TETEGQKLEYEQLLDIK.L "sp|Q7Z3Z0|K1C25_HUMAN,sp|Q7Z3Y8|K1C27_HUMAN" 2 2036.0314 14.49 71162 20509 3 2036.033337 679.6844 "Keratin, type I cytoskeletal 25 OS=Homo sapiens OX=9606 GN=KRT25 PE=1 SV=1" 4.25 3372.2 - 234016 - - - 0.9676 - 1.897 0.371 - 120.9 1 2 1 0.002 17 0 0 0 4.19E+06 2.89E+05 - - - 4.2933 1 221125_WJC_METTL3_EV_vs_WT_F05.20511.20511.3 6.14E-07 Sep-64 R.GTSYQSPHGIPIDLLDR[166.11].L "sp|Q9Y230|RUVB2_HUMAN,tr|M0R0Y3|M0R0Y3_HUMAN" 2 1877.9511 0.95 71164 20511 3 1877.952226 626.991 RuvB-like 2 OS=Homo sapiens OX=9606 GN=RUVBL2 PE=1 SV=3 5.21 3372.5 - 111635 - - - 0.6012 - 2.112 0.517 - 77.7 1 2 0 0.0011 17 0 0 0 2.40E+06 2.53E+06 - - - 6.1925 1 221125_WJC_METTL3_EV_vs_WT_F05.20515.20515.3 1.19E-10 29/80 R.TTSSAIYMNLASHIQPGTVNR.V "sp|Q8WXI9|P66B_HUMAN,tr|A0A0U1RRM1|A0A0U1RRM1_HUMAN,tr|A0A0U1RR30|A0A0U1RR30_HUMAN" 3 2260.127 1.59 71166 20515 3 2260.134204 754.3829 Transcriptional repressor p66-beta OS=Homo sapiens OX=9606 GN=GATAD2B PE=1 SV=1 8.44 3373 - 1.97E+06 - - - 3.1808 - 4.693 0.648 - 1055.8 1 2 0 0.0072 21 0 0 0 3.83E+07 2.41E+07 - - - 9.4692 0.9999 221125_WJC_METTL3_EV_vs_WT_F05.20517.20517.3 1.80E-07 15/56 K.SYEALVQHVIEDHER[166.11].L "sp|Q9H2P0|ADNP_HUMAN,tr|A0A2R8Y6X0|A0A2R8Y6X0_HUMAN,tr|A0A669KBJ7|A0A669KBJ7_HUMAN" 3 1833.8885 0.96 71168 20517 3 1833.893423 612.3034 Activity-dependent neuroprotector homeobox protein OS=Homo sapiens OX=9606 GN=ADNP PE=1 SV=1 4.8 3373.3 - 568646 - - - 2.6866 - 2.392 0.586 - 177.4 1 2 0 0.0049 15 0 0 0 5.36E+06 5.58E+06 - - - 7.3477 0.9997 221125_WJC_METTL3_EV_vs_WT_F05.20518.20518.3 2.63E-08 14/72 K.GIVDQSQQAYQEAFEISKK.E "sp|P63104|1433Z_HUMAN,tr|H0YB80|H0YB80_HUMAN,tr|E7EX29|E7EX29_HUMAN,tr|B7Z2E6|B7Z2E6_HUMAN,tr|B0AZS6|B0AZS6_HUMAN" 5 2168.075 1.1 71169 20518 3 2168.08537 723.6989 14-3-3 protein zeta\delta OS=Homo sapiens OX=9606 GN=YWHAZ PE=1 SV=1 4.68 3373.4 - 421029 - - - 4.8001 - 2.988 0.537 - 243.4 1 2 0 0.0104 19 0 0 0 1.31E+07 1.18E+07 - - - 7.2134 0.999 221125_WJC_METTL3_EV_vs_WT_F05.20519.20519.4 0.000445 19/120 R.TTSSAIYMNLASHIQPGTVNR.V "sp|Q8WXI9|P66B_HUMAN,tr|A0A0U1RRM1|A0A0U1RRM1_HUMAN,tr|A0A0U1RR30|A0A0U1RR30_HUMAN" 3 2260.127 2.13 71170 20519 4 2260.137682 566.039 Transcriptional repressor p66-beta OS=Homo sapiens OX=9606 GN=GATAD2B PE=1 SV=1 8.44 3373.5 - 346771 - - - 4.7196 - 3.459 0.413 - 194.6 1 2 0 0.0107 21 0 0 0 3.82E+06 1.79E+06 - - - 3.2281 1 221125_WJC_METTL3_EV_vs_WT_F05.20520.20520.3 3.85E-12 20/56 R.R[166.11]DFNHINVELSLLGK[136.11].K "sp|P32969|RL9_HUMAN,tr|D6RAN4|D6RAN4_HUMAN,tr|A0A2R8Y5Y7|A0A2R8Y5Y7_HUMAN" 3 1771.97 0.97 71171 20520 3 1771.974579 591.6639 60S ribosomal protein L9 OS=Homo sapiens OX=9606 GN=RPL9 PE=1 SV=1 6.75 3373.7 - 337814 - - - 2.5909 - 3.567 0.664 - 876.1 1 2 0 0.0046 15 0 0 0 3.34E+06 3.45E+06 - - - 9.2601 1 221125_WJC_METTL3_EV_vs_WT_F05.20528.20528.3 1.02E-11 26/80 R.TTSSAIYMNLASHIQPGTVNR[166.11].V "sp|Q8WXI9|P66B_HUMAN,tr|A0A0U1RRM1|A0A0U1RRM1_HUMAN,tr|A0A0U1RR30|A0A0U1RR30_HUMAN" 3 2270.1353 1.57 71177 20528 3 2270.141099 757.719 Transcriptional repressor p66-beta OS=Homo sapiens OX=9606 GN=GATAD2B PE=1 SV=1 8.44 3374.6 - 2.09E+06 - - - 2.5611 - 4.301 0.614 - 760.1 1 2 0 0.0058 21 0 0 0 3.84E+07 2.45E+07 - - - 8.8814 1 221125_WJC_METTL3_EV_vs_WT_F05.20529.20529.3 7.34E-11 19/72 K.GIVDQSQQAYQEAFEISK[136.11]K[136.11].E "sp|P63104|1433Z_HUMAN,tr|H0YB80|H0YB80_HUMAN,tr|E7EX29|E7EX29_HUMAN,tr|B7Z2E6|B7Z2E6_HUMAN,tr|B0AZS6|B0AZS6_HUMAN" 5 2184.1034 1.11 71178 20529 3 2184.108001 729.0417 14-3-3 protein zeta\delta OS=Homo sapiens OX=9606 GN=YWHAZ PE=1 SV=1 4.68 3374.8 - 766248 - - - 2.1235 - 3.865 0.632 - 452.3 1 2 0 0.0046 19 0 0 0 1.32E+07 1.18E+07 - - - 8.9064 1 221125_WJC_METTL3_EV_vs_WT_F05.20536.20536.3 1.36E-09 17/100 R.LQEALDAEMLEDEAGGGGAGPGGAC[160.03]K.A "sp|Q1KMD3|HNRL2_HUMAN,tr|H3BQZ7|H3BQZ7_HUMAN" 2 2502.1003 1.68 71185 20536 3 2502.106774 835.0407 Heterogeneous nuclear ribonucleoprotein U-like protein 2 OS=Homo sapiens OX=9606 GN=HNRNPUL2 PE=1 SV=1 3.77 3375.7 - 232215 - - - 2.6002 - 3.415 0.715 - 250.1 1 2 0 0.0065 26 0 0 0 1.53E+06 9.11E+05 - - - 9.3353 0.9999 221125_WJC_METTL3_EV_vs_WT_F05.20542.20542.3 5.27E-09 Nov-92 K.DNLELPSAEHQAIESSQASVETWK.Y "sp|Q96DF8|ESS2_HUMAN,tr|F8WEF8|F8WEF8_HUMAN" 2 2668.2617 2.05 71191 20542 3 2668.270895 890.4278 Splicing factor ESS-2 homolog OS=Homo sapiens OX=9606 GN=ESS2 PE=1 SV=1 4.25 3376.5 - 133951 - - - 3.4633 - 2.501 0.639 - 69.9 1 2 0 0.0092 24 0 0 0 1.55E+06 7.54E+05 - - - 7.7908 0.9995 221125_WJC_METTL3_EV_vs_WT_F05.20548.20548.4 1.09E-09 28/102 R.NKESPVFAPVYFPEELHR.K "sp|P09601|HMOX1_HUMAN,tr|B1AHA8|B1AHA8_HUMAN,tr|A0A7I2V3I1|A0A7I2V3I1_HUMAN" 3 2158.0847 1.56 71195 20548 4 2158.093892 540.5285 Heme oxygenase 1 OS=Homo sapiens OX=9606 GN=HMOX1 PE=1 SV=1 5.5 3377.3 - 741817 - - - 4.2408 - 3.606 0.588 - 608.4 1 2 1 0.0092 18 0 0 0 6.22E+06 3.98E+06 - - - 4.7808 0.9997 221125_WJC_METTL3_EV_vs_WT_F05.20549.20549.4 1.37E-08 22/102 R.NK[136.11]ESPVFAPVYFPEELHR[166.11].K "sp|P09601|HMOX1_HUMAN,tr|B1AHA8|B1AHA8_HUMAN,tr|A0A7I2V3I1|A0A7I2V3I1_HUMAN" 3 2176.1072 1.63 71196 20549 4 2176.113119 545.0341 Heme oxygenase 1 OS=Homo sapiens OX=9606 GN=HMOX1 PE=1 SV=1 5.5 3377.4 - 476267 - - - 2.7154 - 3.435 0.503 - 403.5 1 2 1 0.0059 18 0 0 0 6.15E+06 3.78E+06 - - - 4.0252 0.9996 221125_WJC_METTL3_EV_vs_WT_F05.20554.20554.3 0.000697 Jul-36 R.K[136.11]QDSGHLDLR[166.11].N "sp|Q86U44|MTA70_HUMAN,tr|B4E349|B4E349_HUMAN,tr|F5H6D8|F5H6D8_HUMAN,tr|B4DTN4|B4DTN4_HUMAN" 4 1185.6221 0.03 71201 20554 3 1185.625793 396.2146 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 6.75 3378.1 - 207491 - - - 3.1106 - 1.824 0.452 - 73.4 1 2 0 0.0037 10 0 0 0 3.76E+04 1.36E+06 - - - 5.3336 1 221125_WJC_METTL3_EV_vs_WT_F05.20555.20555.3 3.00E-09 16/64 R.HFIMQVVC[160.03]EATQC[160.03]PDTR[166.11].V "sp|Q14974|IMB1_HUMAN,tr|J3KTM9|J3KTM9_HUMAN" 2 2100.9419 0.88 71202 20555 3 2100.944889 701.3212 Importin subunit beta-1 OS=Homo sapiens OX=9606 GN=KPNB1 PE=1 SV=2 5.32 3378.2 - 124295 - - - 1.4365 - 3.263 0.66 - 404.8 1 2 0 0.003 17 0 0 0 3.99E+06 4.52E+06 - - - 8.8852 0.9983 221125_WJC_METTL3_EV_vs_WT_F05.20559.20559.3 5.84E-07 Dec-48 R.K[136.11]IEEIK[136.11]DFLLTAR[166.11].R "sp|P63173|RL38_HUMAN,tr|J3KT73|J3KT73_HUMAN,tr|J3QL01|J3QL01_HUMAN,tr|J3KSP2|J3KSP2_HUMAN" 4 1600.9399 1.19 71205 20559 3 1600.945867 534.6539 60S ribosomal protein L38 OS=Homo sapiens OX=9606 GN=RPL38 PE=1 SV=2 6.18 3378.7 - 407191 - - - 3.7503 - 2.207 0.456 - 185.5 1 2 1 0.006 13 0 0 0 5.52E+06 4.62E+06 - - - 5.7686 0.9999 221125_WJC_METTL3_EV_vs_WT_F05.20561.20561.3 3.34E-06 16/88 K.SPTMEQAVQTASAHLPAPAAVGR[166.11].R sp|Q8ND56|LS14A_HUMAN 1 2299.1618 1.19 71206 20561 3 2299.16624 767.3946 Protein LSM14 homolog A OS=Homo sapiens OX=9606 GN=LSM14A PE=1 SV=3 6.47 3378.9 - 579353 - - - 1.9164 - 2.508 0.465 - 136.1 1 2 0 0.0044 23 0 0 0 9.65E+07 8.10E+07 - - - 5.8801 1 221125_WJC_METTL3_EV_vs_WT_F05.20564.20564.3 4.88E-08 13/84 R.DSLLATVPDEQDC[160.03]VTQEVPDSR.Q sp|Q96RS0|TGS1_HUMAN 1 2473.1279 3.38 71209 20564 3 2473.132168 825.3832 Trimethylguanosine synthase OS=Homo sapiens OX=9606 GN=TGS1 PE=1 SV=3 3.66 3379.3 - 295871 - - - 1.7407 - 2.426 0.607 - 154.4 1 2 0 0.0043 22 0 0 0 7.82E+06 2.31E+06 - - - 7.4074 0.9996 221125_WJC_METTL3_EV_vs_WT_F05.20566.20566.4 8.07E-09 16/108 R.GSDVIIMLVGNKTDLADKR.Q "sp|P20340|RAB6A_HUMAN,sp|Q9NRW1|RAB6B_HUMAN,tr|J3KR73|J3KR73_HUMAN,tr|C9JU14|C9JU14_HUMAN" 4 2044.0987 0.91 71211 20566 4 2044.106859 512.0319 Ras-related protein Rab-6A OS=Homo sapiens OX=9606 GN=RAB6A PE=1 SV=3 6.04 3379.6 - 258955 - - - 4.0037 - 3.425 0.585 - 181.2 1 2 1 0.0082 19 0 0 0 2.12E+06 2.33E+06 - - - 4.732 0.9999 221125_WJC_METTL3_EV_vs_WT_F05.20567.20567.3 0.000249 16/64 R.HFIMQVVC[160.03]EATQC[160.03]PDTR.V "sp|Q14974|IMB1_HUMAN,tr|J3KTM9|J3KTM9_HUMAN" 2 2090.9336 0.88 71212 20567 3 2090.9413 697.9851 Importin subunit beta-1 OS=Homo sapiens OX=9606 GN=KPNB1 PE=1 SV=2 5.32 3379.7 - 213657 - - - 3.6821 - 3.498 0.598 - 345.5 1 2 0 0.0077 17 0 0 0 3.99E+06 4.52E+06 - - - 8.3684 0.9998 221125_WJC_METTL3_EV_vs_WT_F05.20568.20568.3 2.88E-05 14/68 R.NK[136.11]ESPVFAPVYFPEELHR[166.11].K "sp|P09601|HMOX1_HUMAN,tr|B1AHA8|B1AHA8_HUMAN,tr|A0A7I2V3I1|A0A7I2V3I1_HUMAN" 3 2176.1072 3.76 71213 20568 3 2176.109819 726.3763 Heme oxygenase 1 OS=Homo sapiens OX=9606 GN=HMOX1 PE=1 SV=1 5.5 3379.8 - 210445 - - - 1.1989 - 2.502 0.487 - 174.6 1 2 1 0.0026 18 0 0 0 5.60E+06 1.49E+06 - - - 6.2525 1 221125_WJC_METTL3_EV_vs_WT_F05.20569.20569.3 3.12E-09 15/84 R.DSLLATVPDEQDC[160.03]VTQEVPDSR[166.11].Q sp|Q96RS0|TGS1_HUMAN 1 2483.1361 3.82 71214 20569 3 2483.136713 828.7193 Trimethylguanosine synthase OS=Homo sapiens OX=9606 GN=TGS1 PE=1 SV=3 3.66 3380 - 161551 - - - 0.2336 - 2.512 0.598 - 205.6 1 2 0 0.0006 22 0 0 0 7.15E+06 1.87E+06 - - - 7.3907 0.999 221125_WJC_METTL3_EV_vs_WT_F05.20577.20577.4 6.06E-06 18/126 K.EIEQEAAVELSQLRDPQHDLDR.V sp|P47985|UCRI_HUMAN 1 2590.2623 1.08 71220 20577 4 2590.271508 648.5729 "Cytochrome b-c1 complex subunit Rieske, mitochondrial OS=Homo sapiens OX=9606 GN=UQCRFS1 PE=1 SV=2" 4.19 3381.1 - 500612 - - - 3.546 - 3.765 0.454 - 197.3 1 2 1 0.0092 22 0 0 0 4.91E+06 4.53E+06 - - - 3.6089 1 221125_WJC_METTL3_EV_vs_WT_F05.20582.20582.3 4.03E-10 15/72 K.QQEC[160.03]PEC[160.03]DVLSLGTYSASR.S sp|Q10469|MGAT2_HUMAN 1 2198.9572 1.86 71225 20582 3 2198.963119 733.993 "Alpha-1,6-mannosyl-glycoprotein 2-beta-N-acetylglucosaminyltransferase OS=Homo sapiens OX=9606 GN=MGAT2 PE=1 SV=1" 4.14 3381.7 - 166878 - - - 2.6767 - 2.697 0.702 - 214.3 1 2 0 0.0059 19 0 0 0 7.85E+06 4.22E+06 - - - 8.8025 0.9991 221125_WJC_METTL3_EV_vs_WT_F05.20587.20587.3 0.0198 Aug-92 R.EQFDTLTPEPPVDPNQEVPPGPPR.F "sp|Q6PKG0|LARP1_HUMAN,tr|A0A0B4J210|A0A0B4J210_HUMAN,tr|H0YC33|H0YC33_HUMAN,tr|E5RH50|E5RH50_HUMAN" 4 2655.2817 4.33 71230 20587 3 2655.285315 886.1012 La-related protein 1 OS=Homo sapiens OX=9606 GN=LARP1 PE=1 SV=2 3.83 3382.3 - 107407 - - - 1.3761 - 1.451 0.38 - 39.7 1 2 0 0.0037 24 0 0 0 1.21E+06 2.79E+05 - - - 3.6402 0.9848 221125_WJC_METTL3_EV_vs_WT_F05.20588.20588.4 0.0116 Jul-72 R.KIEEIKDFLLTAR.R "sp|P63173|RL38_HUMAN,tr|J3KT73|J3KT73_HUMAN,tr|J3QL01|J3QL01_HUMAN,tr|J3KSP2|J3KSP2_HUMAN" 4 1574.9032 0.98 71231 20588 4 1574.91064 394.7331 60S ribosomal protein L38 OS=Homo sapiens OX=9606 GN=RPL38 PE=1 SV=2 6.18 3382.5 - 101511 - - - 4.7285 - 1.576 0.36 - 49.6 1 2 1 0.0074 13 0 0 0 1.68E+06 1.72E+06 - - - 2.526 1 221125_WJC_METTL3_EV_vs_WT_F05.20594.20594.3 0.000139 13/68 K.EIQSSNLETAMSVIGDR[166.11]R[166.11].S sp|Q9NX55|HYPK_HUMAN 1 2025.0064 0.03 71235 20594 3 2025.008387 676.0094 Huntingtin-interacting protein K OS=Homo sapiens OX=9606 GN=HYPK PE=1 SV=2 4.68 3383.3 - 510327 - - - 0.9847 - 2.539 0.483 - 187.9 1 2 0 0.002 18 0 0 0 2.17E+05 7.79E+06 - - - 6.2446 1 221125_WJC_METTL3_EV_vs_WT_F05.20596.20596.3 2.38E-11 19/72 K.DWC[160.03]YEATYSQLAHPIQQAK[136.11].A sp|O43615|TIM44_HUMAN 1 2316.0725 0.82 71237 20596 3 2316.074015 773.0314 Mitochondrial import inner membrane translocase subunit TIM44 OS=Homo sapiens OX=9606 GN=TIMM44 PE=1 SV=2 5.32 3383.5 - 730880 - - - 0.6684 - 3.217 0.658 - 381.7 1 2 0 0.0015 19 0 0 0 4.02E+06 4.92E+06 - - - 8.7463 0.9969 221125_WJC_METTL3_EV_vs_WT_F05.20597.20597.3 3.40E-05 15/72 F.GEEGLTLNLEDVQPHDLGK[136.11].V "sp|P10809|CH60_HUMAN,tr|A0A7I2V2X6|A0A7I2V2X6_HUMAN,tr|A0A7I2YQK6|A0A7I2YQK6_HUMAN,tr|A0A7I2V599|A0A7I2V599_HUMAN" 4 2071.0313 0.68 71238 20597 3 2071.032974 691.351 "60 kDa heat shock protein, mitochondrial OS=Homo sapiens OX=9606 GN=HSPD1 PE=1 SV=2" 4.17 3383.7 - 590128 - - - 0.8015 - 2.658 0.502 - 259.5 1 1 0 0.0017 19 0 0 0 8.13E+06 1.19E+07 - - - 6.538 0.9975 221125_WJC_METTL3_EV_vs_WT_F05.20598.20598.4 0.00092 11/108 K.GQSLGYAFAEFQEHEHALK[136.11].A sp|Q9NW13|RBM28_HUMAN 1 2169.0371 1.24 71239 20598 4 2169.04138 543.2665 RNA-binding protein 28 OS=Homo sapiens OX=9606 GN=RBM28 PE=1 SV=3 5.33 3383.8 - 415685 - - - 1.988 - 2.133 0.274 - 91.6 1 2 0 0.0043 19 0 0 0 2.74E+06 2.20E+06 - - - 1.866 0.9971 221125_WJC_METTL3_EV_vs_WT_F05.20599.20599.4 9.80E-06 11/102 K.IKVDEFVTHNLSFDEINK.A sp|P11766|ADHX_HUMAN 1 2147.0899 1.26 71240 20599 4 2147.099007 537.7797 Alcohol dehydrogenase class-3 OS=Homo sapiens OX=9606 GN=ADH5 PE=1 SV=4 4.75 3383.9 - 339322 - - - 4.2485 - 2.388 0.427 - 70.6 1 2 1 0.0091 18 0 0 0 1.69E+06 1.34E+06 - - - 3.2383 0.9996 221125_WJC_METTL3_EV_vs_WT_F05.20601.20601.4 1.70E-05 12/126 K.LK[136.11]DDQTLDFYGIQPGSTVHVLR[166.11].K "sp|Q96S82|UBL7_HUMAN,tr|H3BV23|H3BV23_HUMAN,tr|H3BUV9|H3BUV9_HUMAN" 3 2519.3139 6.57 71242 20601 4 2519.319374 630.8358 Ubiquitin-like protein 7 OS=Homo sapiens OX=9606 GN=UBL7 PE=1 SV=2 5.3 3384.2 - 232467 - - - 2.1696 - 2.952 0.462 - 72.4 1 2 1 0.0055 22 0 0 0 9.41E+06 1.43E+06 - - - 3.5999 1 221125_WJC_METTL3_EV_vs_WT_F05.20602.20602.2 2.53E-14 15/36 K.QQEC[160.03]PEC[160.03]DVLSLGTYSASR.S sp|Q10469|MGAT2_HUMAN 1 2198.9572 1.78 71243 20602 2 2198.96389 1100.4859 "Alpha-1,6-mannosyl-glycoprotein 2-beta-N-acetylglucosaminyltransferase OS=Homo sapiens OX=9606 GN=MGAT2 PE=1 SV=1" 4.14 3384.3 - 129176 - - - 3.0273 - 3.136 0.751 - 559.4 1 2 0 0.0067 19 0 0 0 2.83E+06 1.59E+06 - - - 7.3958 1 221125_WJC_METTL3_EV_vs_WT_F05.20603.20603.2 0.00178 16/34 R.DVQIGDIVTVGEC[160.03]R[166.11]PLSK[136.11].T "sp|P62280|RS11_HUMAN,tr|M0R1H5|M0R1H5_HUMAN" 2 2003.0476 1.42 71244 20603 2 2003.049992 1002.5311 40S ribosomal protein S11 OS=Homo sapiens OX=9606 GN=RPS11 PE=1 SV=3 4.56 3384.4 - 123948 - - - 1.1712 - 3.224 0.553 - 709.1 1 2 0 0.0023 18 0 0 0 4.95E+06 3.49E+06 - - - 6.0028 0.9861 221125_WJC_METTL3_EV_vs_WT_F05.20607.20607.3 4.59E-06 17/72 F.GEEGLTLNLEDVQPHDLGK.V "sp|P10809|CH60_HUMAN,tr|A0A7I2V2X6|A0A7I2V2X6_HUMAN,tr|A0A7I2YQK6|A0A7I2YQK6_HUMAN,tr|A0A7I2V599|A0A7I2V599_HUMAN" 4 2063.0171 0.68 71246 20607 3 2063.022049 688.6796 "60 kDa heat shock protein, mitochondrial OS=Homo sapiens OX=9606 GN=HSPD1 PE=1 SV=2" 4.17 3385 - 729617 - - - 2.3921 - 2.766 0.43 - 320.8 1 1 0 0.0049 19 0 0 0 8.13E+06 1.19E+07 - - - 5.8323 0.9999 221125_WJC_METTL3_EV_vs_WT_F05.20608.20608.3 2.66E-10 19/64 R.EGIVTATEQEVKEDIAK.L "sp|Q12931|TRAP1_HUMAN,tr|I3L0K7|I3L0K7_HUMAN" 2 1858.9524 1.98 71247 20608 3 1858.955501 620.6581 "Heat shock protein 75 kDa, mitochondrial OS=Homo sapiens OX=9606 GN=TRAP1 PE=1 SV=3" 4.25 3385.1 - 667462 - - - 1.6746 - 3.893 0.58 - 780.9 1 2 1 0.0031 17 0 0 0 2.30E+07 1.16E+07 - - - 8.4393 1 221125_WJC_METTL3_EV_vs_WT_F05.20609.20609.3 7.11E-08 15/72 K.DWC[160.03]YEATYSQLAHPIQQAK.A sp|O43615|TIM44_HUMAN 1 2308.0583 0.8 71248 20609 3 2308.052845 770.36 Mitochondrial import inner membrane translocase subunit TIM44 OS=Homo sapiens OX=9606 GN=TIMM44 PE=1 SV=2 5.32 3385.2 - 706807 - - - -2.3492 - 2.462 0.568 - 165.7 1 2 0 -0.0054 19 0 0 0 4.39E+06 5.47E+06 - - - 7.0846 1 221125_WJC_METTL3_EV_vs_WT_F05.20610.20610.3 6.48E-14 23/72 K.K[136.11]PVVDC[160.03]VVSVPC[160.03]FYTDAER[166.11].R "sp|P34932|HSP74_HUMAN,tr|A0A087WTS8|A0A087WTS8_HUMAN,tr|A0A087WYC1|A0A087WYC1_HUMAN" 3 2258.083 0.05 71249 20610 3 2258.094574 753.7016 Heat shock 70 kDa protein 4 OS=Homo sapiens OX=9606 GN=HSPA4 PE=1 SV=4 4.56 3385.4 - 549329 - - - 5.1052 - 4.235 0.724 - 646.4 1 2 0 0.0115 19 0 0 0 4.23E+05 7.83E+06 - - - 10.1548 1 221125_WJC_METTL3_EV_vs_WT_F05.20611.20611.3 3.02E-06 15/60 R.SQEGRPVQVIGALIGK.Q "sp|Q7L5N1|CSN6_HUMAN,tr|E7EM64|E7EM64_HUMAN" 2 1650.9417 1.14 71250 20611 3 1650.945839 551.3212 COP9 signalosome complex subunit 6 OS=Homo sapiens OX=9606 GN=COPS6 PE=1 SV=1 8.46 3385.5 - 372183 - - - 2.5046 - 3.192 0.511 - 302.9 1 2 0 0.0041 16 0 0 0 1.86E+07 1.63E+07 - - - 7.2141 0.9999 221125_WJC_METTL3_EV_vs_WT_F05.20613.20613.3 1.84E-05 17/60 K.K[136.11]PELVISYLPPGMASK[136.11].L "sp|P78347|GTF2I_HUMAN,tr|A0A494C1K3|A0A494C1K3_HUMAN" 2 1744.9768 1.84 71252 20613 3 1744.979888 582.6662 General transcription factor II-I OS=Homo sapiens OX=9606 GN=GTF2I PE=1 SV=2 8.5 3385.8 - 318530 - - - 1.753 - 2.44 0.474 - 251.4 1 2 0 0.0031 16 0 0 0 1.02E+07 5.56E+06 - - - 6.1125 1 221125_WJC_METTL3_EV_vs_WT_F05.20614.20614.2 4.51E-08 18/34 R.DVQIGDIVTVGEC[160.03]RPLSK.T "sp|P62280|RS11_HUMAN,tr|M0R1H5|M0R1H5_HUMAN" 2 1985.0252 1.42 71253 20614 2 1985.02706 993.5199 40S ribosomal protein S11 OS=Homo sapiens OX=9606 GN=RPS11 PE=1 SV=3 4.56 3385.9 - 301528 - - - 0.9491 - 3.393 0.55 - 911.2 1 2 0 0.0019 18 0 0 0 4.95E+06 3.49E+06 - - - 6.1063 0.9999 221125_WJC_METTL3_EV_vs_WT_F05.20619.20619.3 1.42E-06 18/64 R.EGIVTATEQEVK[136.11]EDIAK[136.11].L "sp|Q12931|TRAP1_HUMAN,tr|I3L0K7|I3L0K7_HUMAN" 2 1874.9808 1.98 71256 20619 3 1874.978452 626.0009 "Heat shock protein 75 kDa, mitochondrial OS=Homo sapiens OX=9606 GN=TRAP1 PE=1 SV=3" 4.25 3386.6 - 1.44E+06 - - - -1.2459 - 3.874 0.503 - 708.8 1 2 1 -0.0023 17 0 0 0 2.30E+07 1.16E+07 - - - 7.5686 0.9974 221125_WJC_METTL3_EV_vs_WT_F05.20624.20624.3 1.67E-07 13/84 K.AAQHDLPASEGEVWSMPVPVER.R "sp|O75449|KTNA1_HUMAN,tr|B7ZBC9|B7ZBC9_HUMAN,tr|B7ZBC8|B7ZBC8_HUMAN" 3 2404.1481 0.53 71261 20624 3 2404.167573 802.39 Katanin p60 ATPase-containing subunit A1 OS=Homo sapiens OX=9606 GN=KATNA1 PE=1 SV=1 4.4 3387.2 - 325554 - - - 8.081 - 2.585 0.518 - 124.8 1 2 0 0.0194 22 0 0 0 8.62E+05 1.62E+06 - - - 6.5614 1 221125_WJC_METTL3_EV_vs_WT_F05.20625.20625.4 3.27E-07 21/114 K.GIHHPTPIQIQGIPTILSGR[166.11].D "sp|Q9UJV9|DDX41_HUMAN,tr|A0A499FJW5|A0A499FJW5_HUMAN,tr|H0Y8L8|H0Y8L8_HUMAN" 3 2144.2094 0.98 71262 20625 4 2144.212806 537.0596 Probable ATP-dependent RNA helicase DDX41 OS=Homo sapiens OX=9606 GN=DDX41 PE=1 SV=2 9.76 3387.3 - 264021 - - - 1.5992 - 3.39 0.609 - 345 1 2 0 0.0034 20 0 0 0 4.40E+06 4.49E+06 - - - 4.9339 0.9996 221125_WJC_METTL3_EV_vs_WT_F05.20626.20626.3 0.000138 Aug-76 R.C[160.03]YYSNTDAVIYVVDSC[160.03]DR[166.11]DR[166.11].L "sp|P40616|ARL1_HUMAN,tr|B4DZG7|B4DZG7_HUMAN,tr|F8VYN9|F8VYN9_HUMAN" 3 2490.0695 0.58 71263 20626 3 2490.067255 831.0304 ADP-ribosylation factor-like protein 1 OS=Homo sapiens OX=9606 GN=ARL1 PE=1 SV=1 4.14 3387.5 - 232698 - - - -0.8871 - 1.696 0.498 - 43.4 1 2 1 -0.0022 20 0 0 0 9.13E+05 1.57E+06 - - - 5.3732 1 221125_WJC_METTL3_EV_vs_WT_F05.20627.20627.3 1.22E-09 Sep-96 R.FAHPADSTMIDTNDNTVTVC[160.03]MDYIK.G "sp|Q9NR56|MBNL1_HUMAN,tr|H7C4T5|H7C4T5_HUMAN,tr|Q86VM6|Q86VM6_HUMAN,tr|H7C4Y1|H7C4Y1_HUMAN,tr|A0A0A0MQX8|A0A0A0MQX8_HUMAN,tr|C9JCX1|C9JCX1_HUMAN,tr|C9JP00|C9JP00_HUMAN" 7 2858.2561 1.9 71264 20627 3 2858.259241 953.7593 Muscleblind-like protein 1 OS=Homo sapiens OX=9606 GN=MBNL1 PE=1 SV=2 4.13 3387.6 - 222808 - - - 1.093 - 2.541 0.705 - 86.2 1 2 0 0.0031 25 0 0 0 1.82E+06 9.57E+05 - - - 8.5447 0.9989 221125_WJC_METTL3_EV_vs_WT_F05.20632.20632.3 0.00402 Nov-48 K.ESQAKDVIEEYFK.C sp|P25398|RS12_HUMAN 1 1584.7672 1.77 71268 20632 3 1584.768469 529.263 40S ribosomal protein S12 OS=Homo sapiens OX=9606 GN=RPS12 PE=1 SV=3 4.41 3388.2 - 3.25E+06 - - - 0.8298 - 1.945 0.37 - 203 1 2 1 0.0013 13 0 0 0 5.02E+07 2.83E+07 - - - 4.4685 0.9992 221125_WJC_METTL3_EV_vs_WT_F05.20634.20634.3 0.000456 Sep-48 K.ESQAK[136.11]DVIEEYFK[136.11].C sp|P25398|RS12_HUMAN 1 1600.7956 1.77 71269 20634 3 1600.797418 534.6058 40S ribosomal protein S12 OS=Homo sapiens OX=9606 GN=RPS12 PE=1 SV=3 4.41 3388.4 - 2.10E+06 - - - 1.1644 - 2.016 0.392 - 134.8 1 2 1 0.0019 13 0 0 0 5.02E+07 2.83E+07 - - - 4.8108 1 221125_WJC_METTL3_EV_vs_WT_F05.20636.20636.3 1.39E-09 14/72 R.MDSFDEDLARPSGLLAQER.K "sp|Q9Y2W1|TR150_HUMAN,tr|A0A3B3ITZ9|A0A3B3ITZ9_HUMAN" 2 2149.011 2.78 71271 20636 3 2149.011235 717.3443 Thyroid hormone receptor-associated protein 3 OS=Homo sapiens OX=9606 GN=THRAP3 PE=1 SV=2 4.1 3388.7 - 584640 - - - 0.1173 - 2.754 0.572 - 240.1 1 2 0 0.0003 19 0 0 0 8.20E+07 2.95E+07 - - - 7.406 1 221125_WJC_METTL3_EV_vs_WT_F05.20637.20637.2 6.91E-09 15/24 K.ESQAKDVIEEYFK.C sp|P25398|RS12_HUMAN 1 1584.7672 1.73 71272 20637 2 1584.771251 793.3909 40S ribosomal protein S12 OS=Homo sapiens OX=9606 GN=RPS12 PE=1 SV=3 4.41 3388.8 - 459045 - - - 2.5852 - 3.128 0.601 - 834.9 1 2 1 0.0041 13 0 0 0 1.05E+07 6.11E+06 - - - 6.4056 1 221125_WJC_METTL3_EV_vs_WT_F05.20639.20639.2 6.42E-08 15/34 K.TVTNAVVTVPAYFNDSQR[166.11].Q "sp|P11142|HSP7C_HUMAN,tr|E9PQQ4|E9PQQ4_HUMAN,tr|E9PN89|E9PN89_HUMAN,tr|E9PLF4|E9PLF4_HUMAN,tr|E9PI65|E9PI65_HUMAN,tr|E9PK54|E9PK54_HUMAN,tr|E9PQK7|E9PQK7_HUMAN" 7 1990.9988 0.15 71274 20639 2 1990.993 996.5067 Heat shock cognate 71 kDa protein OS=Homo sapiens OX=9606 GN=HSPA8 PE=1 SV=1 5.5 3389.1 - 211175 - - - -2.9006 - 2.804 0.592 - 460 1 2 0 -0.0058 18 0 0 0 8.98E+06 5.89E+07 - - - 5.9466 1 221125_WJC_METTL3_EV_vs_WT_F05.20645.20645.3 9.24E-06 18/68 R.DVQIGDIVTVGEC[160.03]RPLSK.T "sp|P62280|RS11_HUMAN,tr|M0R1H5|M0R1H5_HUMAN" 2 1985.0252 1.03 71278 20645 3 1985.030363 662.6823 40S ribosomal protein S11 OS=Homo sapiens OX=9606 GN=RPS11 PE=1 SV=3 4.56 3389.9 - 9.80E+06 - - - 2.6131 - 3.52 0.582 - 297.7 1 2 0 0.0052 18 0 0 0 1.96E+08 1.90E+08 - - - 8.161 1 221125_WJC_METTL3_EV_vs_WT_F05.20646.20646.3 2.00E-09 18/72 R.MDSFDEDLAR[166.11]PSGLLAQER[166.11].K "sp|Q9Y2W1|TR150_HUMAN,tr|A0A3B3ITZ9|A0A3B3ITZ9_HUMAN" 2 2169.0275 2.76 71279 20646 3 2169.030575 724.0165 Thyroid hormone receptor-associated protein 3 OS=Homo sapiens OX=9606 GN=THRAP3 PE=1 SV=2 4.1 3390 - 915572 - - - 1.4071 - 3.242 0.663 - 386.8 1 2 0 0.0031 19 0 0 0 8.17E+07 2.96E+07 - - - 8.8206 0.9997 221125_WJC_METTL3_EV_vs_WT_F05.20647.20647.4 3.29E-06 19/132 K.SPTMEQAVQTASAHLPAPAAVGR.R sp|Q8ND56|LS14A_HUMAN 1 2289.1536 5.83 71280 20647 4 2289.164704 573.2957 Protein LSM14 homolog A OS=Homo sapiens OX=9606 GN=LSM14A PE=1 SV=3 6.47 3390.1 - 410089 - - - 4.8664 - 2.788 0.521 - 185.2 1 2 0 0.0111 23 0 0 0 5.42E+07 9.30E+06 - - - 4.0899 0.9997 221125_WJC_METTL3_EV_vs_WT_F05.20654.20654.3 1.09E-06 15/60 R.SQEGR[166.11]PVQVIGALIGK[136.11].Q "sp|Q7L5N1|CSN6_HUMAN,tr|E7EM64|E7EM64_HUMAN" 2 1668.9642 1.14 71285 20654 3 1668.970381 557.3287 COP9 signalosome complex subunit 6 OS=Homo sapiens OX=9606 GN=COPS6 PE=1 SV=1 8.46 3391.1 - 1.19E+06 - - - 3.7191 - 2.897 0.42 - 304.9 1 2 0 0.0062 16 0 0 0 1.86E+07 1.63E+07 - - - 5.9501 1 221125_WJC_METTL3_EV_vs_WT_F05.20657.20657.3 9.61E-14 15/112 K.SALPYSSFSSDQGLGESSAAPSQPITAVK.D "sp|P49750|YLPM1_HUMAN,tr|H0YIQ2|H0YIQ2_HUMAN,tr|F8VU51|F8VU51_HUMAN" 3 2881.3981 2.15 71288 20657 3 2881.404285 961.4733 YLP motif-containing protein 1 OS=Homo sapiens OX=9606 GN=YLPM1 PE=1 SV=4 4.37 3391.5 - 305434 - - - 2.1299 - 3.078 0.688 - 125.3 1 2 0 0.0061 29 0 0 0 8.26E+06 3.84E+06 - - - 8.7954 0.8046 221125_WJC_METTL3_EV_vs_WT_F05.20660.20660.2 1.39 16-Apr R.LSNIFVIGK[136.11].G sp|P62701|RS4X_HUMAN 1 997.6052 1.03 71291 20660 2 997.605991 499.8099 "40S ribosomal protein S4, X isoform OS=Homo sapiens OX=9606 GN=RPS4X PE=1 SV=2" 8.75 3391.9 - 71654.7 - - - 0.826 - 0.939 0.027 - 33.1 5 2 0 0.0008 9 0 0 0 8.92E+05 8.64E+05 - - - -1.2542 0.9999 221125_WJC_METTL3_EV_vs_WT_F05.20662.20662.3 3.87E-06 19/68 R.DVQIGDIVTVGEC[160.03]R[166.11]PLSK[136.11].T "sp|P62280|RS11_HUMAN,tr|M0R1H5|M0R1H5_HUMAN" 2 2003.0476 1.03 71292 20662 3 2003.053419 668.6898 40S ribosomal protein S11 OS=Homo sapiens OX=9606 GN=RPS11 PE=1 SV=3 4.56 3392.1 - 1.18E+06 - - - 2.8821 - 3.508 0.53 - 376.8 1 2 0 0.0058 18 0 0 0 1.96E+08 1.90E+08 - - - 7.5726 0.9999 221125_WJC_METTL3_EV_vs_WT_F05.20665.20665.4 1.92E-06 17/126 R.TGFINLDK[136.11]PSNPSSHEVVAWIR[166.11].R "sp|O60832|DKC1_HUMAN,tr|H7C2Q9|H7C2Q9_HUMAN,tr|C9IYT0|C9IYT0_HUMAN,tr|H7C0M1|H7C0M1_HUMAN" 4 2484.288 0.75 71294 20665 4 2484.298566 622.0793 H\ACA ribonucleoprotein complex subunit DKC1 OS=Homo sapiens OX=9606 GN=DKC1 PE=1 SV=3 6.42 3392.4 - 562139 - - - 4.2419 - 3.851 0.574 - 208.8 1 2 0 0.0105 22 0 0 0 4.23E+06 5.64E+06 - - - 4.6604 0.9786 221125_WJC_METTL3_EV_vs_WT_F05.20672.20672.3 0.000748 Sep-48 R.KIEEIKDFLLTAR.R "sp|P63173|RL38_HUMAN,tr|J3KT73|J3KT73_HUMAN,tr|J3QL01|J3QL01_HUMAN,tr|J3KSP2|J3KSP2_HUMAN" 4 1574.9032 1.24 71301 20672 3 1574.91093 525.975 60S ribosomal protein L38 OS=Homo sapiens OX=9606 GN=RPL38 PE=1 SV=2 6.18 3393.4 - 125821 - - - 4.9127 - 1.714 0.378 - 102.7 1 2 1 0.0077 13 0 0 0 2.63E+06 2.13E+06 - - - 4.2131 0.9997 221125_WJC_METTL3_EV_vs_WT_F05.20676.20676.3 1.39E-06 14/68 K.TVTNAVVTVPAYFNDSQR.Q "sp|P11142|HSP7C_HUMAN,tr|E9PQQ4|E9PQQ4_HUMAN,tr|E9PN89|E9PN89_HUMAN,tr|E9PLF4|E9PLF4_HUMAN,tr|E9PI65|E9PI65_HUMAN,tr|E9PK54|E9PK54_HUMAN,tr|E9PQK7|E9PQK7_HUMAN" 7 1980.9905 0.16 71303 20676 3 1980.99896 661.3374 Heat shock cognate 71 kDa protein OS=Homo sapiens OX=9606 GN=HSPA8 PE=1 SV=1 5.5 3393.8 - 640947 - - - 4.2681 - 2.711 0.504 - 211.8 1 2 0 0.0085 18 0 0 0 2.90E+07 1.77E+08 - - - 6.6402 1 221125_WJC_METTL3_EV_vs_WT_F05.20677.20677.3 1.50E-08 24/96 K.VFNNIGADLLTGSESENKEDGLQNK.H "sp|Q6P3W7|SCYL2_HUMAN,tr|F8VSC5|F8VSC5_HUMAN,tr|A0A0U1RQQ9|A0A0U1RQQ9_HUMAN" 3 2691.2988 2.18 71304 20677 3 2691.306104 898.1069 SCY1-like protein 2 OS=Homo sapiens OX=9606 GN=SCYL2 PE=1 SV=1 4.18 3393.9 - 647464 - - - 2.7258 - 4.827 0.669 - 679.2 1 2 1 0.0073 25 0 0 0 1.56E+07 7.17E+06 - - - 9.6184 1 221125_WJC_METTL3_EV_vs_WT_F05.20678.20678.3 3.84E-07 20/56 R.HFTIDDFEIGR[166.11]PLGK[136.11].G "sp|Q96GD4|AURKB_HUMAN,tr|J3QR41|J3QR41_HUMAN,tr|J3KRJ2|J3KRJ2_HUMAN,tr|J3QLN8|J3QLN8_HUMAN,tr|J3KRF8|J3KRF8_HUMAN,tr|J3KTD6|J3KTD6_HUMAN,tr|J3KT86|J3KT86_HUMAN" 7 1761.9169 0.88 71305 20678 3 1761.9219 588.3129 Aurora kinase B OS=Homo sapiens OX=9606 GN=AURKB PE=1 SV=3 5.38 3394.1 - 544728 - - - 2.8435 - 3.696 0.593 - 544.4 1 2 0 0.005 15 0 0 0 5.56E+06 6.29E+06 - - - 8.5611 1 221125_WJC_METTL3_EV_vs_WT_F05.20679.20679.3 4.27E-12 16/112 K.SALPYSSFSSDQGLGESSAAPSQPITAVK[136.11].D "sp|P49750|YLPM1_HUMAN,tr|H0YIQ2|H0YIQ2_HUMAN,tr|F8VU51|F8VU51_HUMAN" 3 2889.4123 2.15 71306 20679 3 2889.418291 964.1447 YLP motif-containing protein 1 OS=Homo sapiens OX=9606 GN=YLPM1 PE=1 SV=4 4.37 3394.2 - 539481 - - - 2.0568 - 3.609 0.609 - 112.2 1 2 0 0.0059 29 0 0 0 8.26E+06 3.84E+06 - - - 8.2808 0.9996 221125_WJC_METTL3_EV_vs_WT_F05.20680.20680.3 2.11E-07 21/68 K.QQLSAEELDAQLDAYNAR[166.11].M "sp|Q86V81|THOC4_HUMAN,tr|E9PB61|E9PB61_HUMAN" 2 2043.9737 0.95 71307 20680 3 2043.986623 682.3318 THO complex subunit 4 OS=Homo sapiens OX=9606 GN=ALYREF PE=1 SV=3 3.92 3394.3 - 510315 - - - 6.3308 - 3.87 0.584 - 585.6 1 2 0 0.0129 18 0 0 0 1.31E+07 1.38E+07 - - - 8.4172 0.977 221125_WJC_METTL3_EV_vs_WT_F05.20681.20681.4 8.70E-06 20/108 K.ISSIQSIVPALEIANAHRK.P "sp|P10809|CH60_HUMAN,tr|A0A7I2V2X6|A0A7I2V2X6_HUMAN,tr|A0A7I2YQK6|A0A7I2YQK6_HUMAN,tr|A0A7I2V599|A0A7I2V599_HUMAN,tr|A0A7I2YQ71|A0A7I2YQ71_HUMAN,tr|A0A7I2V5M1|A0A7I2V5M1_HUMAN,tr|A0A7I2V5K3|A0A7I2V5K3_HUMAN,tr|A0A7I2V369|A0A7I2V369_HUMAN" 8 2046.1586 1.26 71308 20681 4 2046.165885 512.5469 "60 kDa heat shock protein, mitochondrial OS=Homo sapiens OX=9606 GN=HSPD1 PE=1 SV=2" 8.75 3394.5 - 327173 - - - 3.5735 - 3.015 0.481 - 259.5 1 1 0 0.0073 19 0 0 0 1.64E+08 1.30E+08 - - - 3.7839 0.9999 221125_WJC_METTL3_EV_vs_WT_F05.20682.20682.3 0.000336 13/88 K.TALAYEC[160.03]FQDQDNSTLALPSDQK.M sp|Q13835|PKP1_HUMAN 1 2614.1857 37.24 71309 20682 3 2614.192341 872.4025 Plakophilin-1 OS=Homo sapiens OX=9606 GN=PKP1 PE=1 SV=2 3.84 3394.6 - 312661 - - - 2.5358 - 2.121 0.502 - 124.2 1 2 0 0.0066 23 0 0 0 1.71E+06 4.59E+04 - - - 5.8989 0.9797 221125_WJC_METTL3_EV_vs_WT_F05.20683.20683.3 0.00884 Jul-48 K.SKDSLVDIIGIC[160.03]K.S "sp|P27694|RFA1_HUMAN,tr|I3L4R8|I3L4R8_HUMAN" 2 1446.7752 1.08 71310 20683 3 1446.778931 483.2657 Replication protein A 70 kDa DNA-binding subunit OS=Homo sapiens OX=9606 GN=RPA1 PE=1 SV=2 5.68 3394.7 - 193055 - - - 2.5678 - 1.68 0.273 - 90.6 1 2 1 0.0037 13 0 0 0 1.70E+06 1.58E+06 - - - 2.9893 0.9977 221125_WJC_METTL3_EV_vs_WT_F05.20684.20684.2 3.28E-05 Nov-34 K.TVTNAVVTVPAYFNDSQR.Q "sp|P11142|HSP7C_HUMAN,tr|E9PQQ4|E9PQQ4_HUMAN,tr|E9PN89|E9PN89_HUMAN,tr|E9PLF4|E9PLF4_HUMAN,tr|E9PI65|E9PI65_HUMAN,tr|E9PK54|E9PK54_HUMAN,tr|E9PQK7|E9PQK7_HUMAN" 7 1980.9905 0.15 71311 20684 2 1981.000091 991.5025 Heat shock cognate 71 kDa protein OS=Homo sapiens OX=9606 GN=HSPA8 PE=1 SV=1 5.5 3394.9 - 123131 - - - 4.839 - 2.165 0.51 - 177.4 1 2 0 0.0096 18 0 0 0 8.98E+06 5.89E+07 - - - 4.7039 0.9812 221125_WJC_METTL3_EV_vs_WT_F05.20685.20685.4 2.16E-05 Sep-96 W.SLRPESLHQVSFLFSDR.G sp|P04040|CATA_HUMAN 1 2017.0381 6.61 71312 20685 4 2017.041825 505.2668 Catalase OS=Homo sapiens OX=9606 GN=CAT PE=1 SV=3 6.47 3395 - 121554 - - - 1.8349 - 1.92 0.422 - 40.3 1 1 0 0.0037 17 0 0 0 1.22E+06 1.84E+05 - - - 3.1245 0.9079 221125_WJC_METTL3_EV_vs_WT_F05.20686.20686.3 0.126 Sep-72 R.QAVLGAGLPISTPC[160.03]TTINK.V "sp|P24752|THIL_HUMAN,tr|A0A5F9ZHJ7|A0A5F9ZHJ7_HUMAN,tr|A0A5F9ZHH9|A0A5F9ZHH9_HUMAN,tr|A0A5F9ZHJ0|A0A5F9ZHJ0_HUMAN,tr|A0A5F9ZHL1|A0A5F9ZHL1_HUMAN,tr|H0YEL7|H0YEL7_HUMAN" 6 1940.0401 0.71 71313 20686 3 1940.050749 647.6873 "Acetyl-CoA acetyltransferase, mitochondrial OS=Homo sapiens OX=9606 GN=ACAT1 PE=1 SV=1" 8.22 3395.1 - 120345 - - - 5.4901 - 1.616 0.234 - 76.5 1 2 0 0.0106 19 0 0 0 1.70E+06 2.40E+06 - - - 2.3251 0.9985 221125_WJC_METTL3_EV_vs_WT_F05.20687.20687.4 0.00273 May-84 R.HFTIDDFEIGRPLGK.G "sp|Q96GD4|AURKB_HUMAN,tr|J3QR41|J3QR41_HUMAN,tr|J3KRJ2|J3KRJ2_HUMAN,tr|J3QLN8|J3QLN8_HUMAN,tr|J3KRF8|J3KRF8_HUMAN,tr|J3KTD6|J3KTD6_HUMAN,tr|J3KT86|J3KT86_HUMAN" 7 1743.8944 0.93 71314 20687 4 1743.901069 436.9809 Aurora kinase B OS=Homo sapiens OX=9606 GN=AURKB PE=1 SV=3 5.38 3395.2 - 78470.1 - - - 3.8127 - 1.283 0.383 - 19.8 1 2 0 0.0066 15 0 0 0 7.70E+05 8.30E+05 - - - 2.647 1 221125_WJC_METTL3_EV_vs_WT_F05.20692.20692.3 7.62E-10 20/68 K.QQLSAEELDAQLDAYNAR.M "sp|Q86V81|THOC4_HUMAN,tr|E9PB61|E9PB61_HUMAN" 2 2033.9654 0.95 71317 20692 3 2033.970782 678.9957 THO complex subunit 4 OS=Homo sapiens OX=9606 GN=ALYREF PE=1 SV=3 3.92 3395.9 - 1.77E+06 - - - 2.6397 - 3.838 0.607 - 503.8 1 2 0 0.0054 18 0 0 0 1.31E+07 1.38E+07 - - - 8.655 1 221125_WJC_METTL3_EV_vs_WT_F05.20693.20693.3 2.91E-09 25/96 K.VFNNIGADLLTGSESENK[136.11]EDGLQNK[136.11].H "sp|Q6P3W7|SCYL2_HUMAN,tr|F8VSC5|F8VSC5_HUMAN,tr|A0A0U1RQQ9|A0A0U1RQQ9_HUMAN" 3 2707.3272 2.18 71318 20693 3 2707.32995 903.4497 SCY1-like protein 2 OS=Homo sapiens OX=9606 GN=SCYL2 PE=1 SV=1 4.18 3396.1 - 989950 - - - 1.0276 - 4.254 0.617 - 723.9 1 2 1 0.0028 25 0 0 0 1.56E+07 7.17E+06 - - - 8.7492 1 221125_WJC_METTL3_EV_vs_WT_F05.20694.20694.3 1.65E-08 Dec-76 K.NGTEDLPYAMKPIDYYTETK.L "sp|Q15738|NSDHL_HUMAN,tr|C9JDR0|C9JDR0_HUMAN" 2 2348.0882 1.05 71319 20694 3 2348.08908 783.7034 "Sterol-4-alpha-carboxylate 3-dehydrogenase, decarboxylating OS=Homo sapiens OX=9606 GN=NSDHL PE=1 SV=2" 4.32 3396.2 - 378546 - - - 0.362 - 2.564 0.642 - 132 1 2 0 0.0009 20 0 0 0 2.61E+06 2.49E+06 - - - 7.9817 0.9983 221125_WJC_METTL3_EV_vs_WT_F05.20695.20695.4 3.18E-06 28/108 K.ISSIQSIVPALEIANAHR[166.11]K[136.11].P "sp|P10809|CH60_HUMAN,tr|A0A7I2V2X6|A0A7I2V2X6_HUMAN,tr|A0A7I2YQK6|A0A7I2YQK6_HUMAN,tr|A0A7I2V599|A0A7I2V599_HUMAN,tr|A0A7I2YQ71|A0A7I2YQ71_HUMAN,tr|A0A7I2V5M1|A0A7I2V5M1_HUMAN,tr|A0A7I2V5K3|A0A7I2V5K3_HUMAN,tr|A0A7I2V369|A0A7I2V369_HUMAN" 8 2064.181 1.26 71320 20695 4 2064.183201 517.0525 "60 kDa heat shock protein, mitochondrial OS=Homo sapiens OX=9606 GN=HSPD1 PE=1 SV=2" 8.75 3396.3 - 361429 - - - 1.0455 - 4.49 0.594 - 716.8 1 1 0 0.0022 19 0 0 0 1.64E+08 1.30E+08 - - - 4.9036 0.9999 221125_WJC_METTL3_EV_vs_WT_F05.20696.20696.3 6.36E-07 Dec-96 R.VHPIPLESGGSSDVVLVSYVPSSQR[166.11].Q "sp|Q9NRF2|SH2B1_HUMAN,tr|B4DLN5|B4DLN5_HUMAN,tr|H3BTT2|H3BTT2_HUMAN,tr|H3BUN7|H3BUN7_HUMAN,tr|F5GXU7|F5GXU7_HUMAN" 5 2618.358 0.51 71321 20696 3 2618.367362 873.7933 SH2B adapter protein 1 OS=Homo sapiens OX=9606 GN=SH2B1 PE=1 SV=3 5.32 3396.5 - 239802 - - - 3.5942 - 2.856 0.542 - 112.8 1 2 0 0.0094 25 0 0 0 6.86E+05 1.34E+06 - - - 6.9945 1 221125_WJC_METTL3_EV_vs_WT_F05.20698.20698.3 1.32E-10 16/76 R.RGTDEC[160.03]AIESIAVAATPIPK.L "sp|P53634|CATC_HUMAN,tr|A0A7I2YQT5|A0A7I2YQT5_HUMAN,tr|A0A7I2V2Q8|A0A7I2V2Q8_HUMAN,tr|A0A7I2V466|A0A7I2V466_HUMAN,tr|A0A7I2V6E3|A0A7I2V6E3_HUMAN" 5 2098.0729 2 71323 20698 3 2098.076973 700.3649 Dipeptidyl peptidase 1 OS=Homo sapiens OX=9606 GN=CTSC PE=1 SV=2 4.68 3396.7 - 212091 - - - 1.9628 - 3.234 0.616 - 315.6 1 2 0 0.0041 20 0 0 0 2.16E+06 1.08E+06 - - - 8.2541 1 221125_WJC_METTL3_EV_vs_WT_F05.20700.20700.3 1.19E-11 13/60 K.HQETMTPAGLSFFQC[160.03]R[166.11].W sp|Q96DV4|RM38_HUMAN 1 1918.8694 1.04 71325 20700 3 1918.873847 640.6304 "39S ribosomal protein L38, mitochondrial OS=Homo sapiens OX=9606 GN=MRPL38 PE=1 SV=2" 6.74 3397 - 154391 - - - 2.3394 - 3 0.634 - 249.2 1 2 0 0.0045 16 0 0 0 2.22E+06 2.14E+06 - - - 8.4261 0.9298 221125_WJC_METTL3_EV_vs_WT_F05.20701.20701.3 0.788 Jul-72 R.QAVLGAGLPISTPC[160.03]TTINK[136.11].V "sp|P24752|THIL_HUMAN,tr|A0A5F9ZHJ7|A0A5F9ZHJ7_HUMAN,tr|A0A5F9ZHH9|A0A5F9ZHH9_HUMAN,tr|A0A5F9ZHJ0|A0A5F9ZHJ0_HUMAN,tr|A0A5F9ZHL1|A0A5F9ZHL1_HUMAN,tr|H0YEL7|H0YEL7_HUMAN" 6 1948.0543 0.8 71326 20701 3 1948.056491 650.3587 "Acetyl-CoA acetyltransferase, mitochondrial OS=Homo sapiens OX=9606 GN=ACAT1 PE=1 SV=1" 8.22 3397.1 - 152894 - - - 1.1257 - 1.188 0.16 - 28.3 1 2 0 0.0022 19 0 0 0 1.67E+06 2.08E+06 - - - 0.7465 0.8574 221125_WJC_METTL3_EV_vs_WT_F05.20703.20703.3 0.0452 4/104 K.DLLSTQPSETLASSDSFASTQPTHSWK.V sp|O75940|SPF30_HUMAN 1 2920.3727 0.93 71328 20703 3 2920.383148 974.4648 Survival of motor neuron-related-splicing factor 30 OS=Homo sapiens OX=9606 GN=SMNDC1 PE=1 SV=1 4.54 3397.4 - 126137 - - - 3.591 - 1.238 0.208 - 8.4 2 2 0 0.0105 27 0 0 0 1.07E+06 1.16E+06 - - - 1.2079 0.9999 221125_WJC_METTL3_EV_vs_WT_F05.20709.20709.3 3.19E-06 16/60 K.K[136.11]DC[160.03]EVVMMIGLPGAGK[136.11].T "sp|Q00839|HNRPU_HUMAN,tr|A0A1W2PQL0|A0A1W2PQL0_HUMAN,tr|A0A1W2PPL4|A0A1W2PPL4_HUMAN,tr|A0A1W2PQ74|A0A1W2PQ74_HUMAN,tr|Q5RI18|Q5RI18_HUMAN,tr|A0A1W2PP35|A0A1W2PP35_HUMAN,tr|A0A1W2PPS1|A0A1W2PPS1_HUMAN,tr|A0A1W2PRZ7|A0A1W2PRZ7_HUMAN,tr|A0A1W2PPH7|A0A1W2PPH7_HUMAN,tr|A0A1W2PQD4|A0A1W2PQD4_HUMAN,tr|A0A1W2PP34|A0A1W2PP34_HUMAN,tr|A0A1X7SBS1|A0A1X7SBS1_HUMAN" 12 1719.8693 1.02 71332 20709 3 1719.876062 574.297 Heterogeneous nuclear ribonucleoprotein U OS=Homo sapiens OX=9606 GN=HNRNPU PE=1 SV=6 6.06 3398.1 - 1.12E+06 - - - 3.9491 - 3.123 0.527 - 287.1 1 2 0 0.0068 16 0 0 0 5.77E+07 5.66E+07 - - - 7.3356 0.9999 221125_WJC_METTL3_EV_vs_WT_F05.20710.20710.3 2.12E-05 16/60 K.KDC[160.03]EVVMMIGLPGAGK.T "sp|Q00839|HNRPU_HUMAN,tr|A0A1W2PQL0|A0A1W2PQL0_HUMAN,tr|A0A1W2PPL4|A0A1W2PPL4_HUMAN,tr|A0A1W2PQ74|A0A1W2PQ74_HUMAN,tr|Q5RI18|Q5RI18_HUMAN,tr|A0A1W2PP35|A0A1W2PP35_HUMAN,tr|A0A1W2PPS1|A0A1W2PPS1_HUMAN,tr|A0A1W2PRZ7|A0A1W2PRZ7_HUMAN,tr|A0A1W2PPH7|A0A1W2PPH7_HUMAN,tr|A0A1W2PQD4|A0A1W2PQD4_HUMAN,tr|A0A1W2PP34|A0A1W2PP34_HUMAN,tr|A0A1X7SBS1|A0A1X7SBS1_HUMAN" 12 1703.8409 1.02 71333 20710 3 1703.847622 568.9542 Heterogeneous nuclear ribonucleoprotein U OS=Homo sapiens OX=9606 GN=HNRNPU PE=1 SV=6 6.06 3398.3 - 1.00E+06 - - - 3.9628 - 3.095 0.544 - 307 1 2 0 0.0068 16 0 0 0 5.78E+07 5.66E+07 - - - 7.5021 1 221125_WJC_METTL3_EV_vs_WT_F05.20711.20711.2 9.31E-11 17/34 K.QQLSAEELDAQLDAYNAR[166.11].M "sp|Q86V81|THOC4_HUMAN,tr|E9PB61|E9PB61_HUMAN" 2 2043.9737 0.84 71334 20711 2 2043.977799 1022.9941 THO complex subunit 4 OS=Homo sapiens OX=9606 GN=ALYREF PE=1 SV=3 3.92 3398.4 - 608430 - - - 2.0137 - 3.736 0.667 - 1137.4 1 2 0 0.0041 18 0 0 0 3.71E+06 4.42E+06 - - - 7.2066 0.9997 221125_WJC_METTL3_EV_vs_WT_F05.20714.20714.4 0.000192 15/108 K.GLDVDSLVIEHIQVNKAPK.M "sp|P18621|RL17_HUMAN,tr|A0A087WWH0|A0A087WWH0_HUMAN,tr|J3QS96|J3QS96_HUMAN,tr|J3QLC8|J3QLC8_HUMAN,tr|J3QQT2|J3QQT2_HUMAN,tr|A0A0A0MRF8|A0A0A0MRF8_HUMAN,tr|J3KRB3|J3KRB3_HUMAN,tr|J3KRX5|J3KRX5_HUMAN,tr|A0A087WXM6|A0A087WXM6_HUMAN,tr|A0A0A6YYL6|A0A0A6YYL6_HUMAN" 10 2074.1423 0.99 71337 20714 4 2074.149097 519.5428 60S ribosomal protein L17 OS=Homo sapiens OX=9606 GN=RPL17 PE=1 SV=3 5.38 3398.8 - 265875 - - - 3.2987 - 2.365 0.576 - 76.7 1 2 1 0.0068 19 0 0 0 1.21E+06 1.23E+06 - - - 4.5288 1 221125_WJC_METTL3_EV_vs_WT_F05.20715.20715.3 4.26E-15 15/84 K.WEDRGPSGQGQGQFLIQQVTLK.L "sp|Q13724|MOGS_HUMAN,tr|A0A3B3IS52|A0A3B3IS52_HUMAN,tr|A0A3B3IRK6|A0A3B3IRK6_HUMAN,tr|A0A3B3IRW2|A0A3B3IRW2_HUMAN" 4 2471.2557 0.78 71338 20715 3 2471.263581 824.7592 Mannosyl-oligosaccharide glucosidase OS=Homo sapiens OX=9606 GN=MOGS PE=1 SV=5 6.07 3398.9 - 260574 - - - 3.1806 - 3.482 0.73 - 184.7 1 2 1 0.0079 22 0 0 0 1.80E+06 2.31E+06 - - - 9.6345 1 221125_WJC_METTL3_EV_vs_WT_F05.20716.20716.3 3.86E-15 17/60 K.HQETMTPAGLSFFQC[160.03]R.W sp|Q96DV4|RM38_HUMAN 1 1908.8611 1.04 71339 20716 3 1908.866724 637.2943 "39S ribosomal protein L38, mitochondrial OS=Homo sapiens OX=9606 GN=MRPL38 PE=1 SV=2" 6.74 3399 - 200439 - - - 2.9525 - 3.649 0.722 - 440.8 1 2 0 0.0056 16 0 0 0 2.22E+06 2.14E+06 - - - 9.9094 0.9872 221125_WJC_METTL3_EV_vs_WT_F05.20718.20718.3 0.022 Jul-72 K.GLDVDSLVIEHIQVNK[136.11]APK[136.11].M "sp|P18621|RL17_HUMAN,tr|A0A087WWH0|A0A087WWH0_HUMAN,tr|J3QS96|J3QS96_HUMAN,tr|J3QLC8|J3QLC8_HUMAN,tr|J3QQT2|J3QQT2_HUMAN,tr|A0A0A0MRF8|A0A0A0MRF8_HUMAN,tr|J3KRB3|J3KRB3_HUMAN,tr|J3KRX5|J3KRX5_HUMAN,tr|A0A087WXM6|A0A087WXM6_HUMAN,tr|A0A0A6YYL6|A0A0A6YYL6_HUMAN" 10 2090.1707 0.77 71341 20718 3 2090.174804 697.7308 60S ribosomal protein L17 OS=Homo sapiens OX=9606 GN=RPL17 PE=1 SV=3 5.38 3399.3 - 139953 - - - 1.985 - 1.412 0.328 - 50.4 1 2 1 0.0041 19 0 0 0 4.67E+05 6.08E+05 - - - 3.0433 1 221125_WJC_METTL3_EV_vs_WT_F05.20722.20722.3 1.12E-13 33/88 K.SPTMEQAVQTASAHLPAPAAVGR.R sp|Q8ND56|LS14A_HUMAN 1 2289.1536 1.2 71344 20722 3 2289.160108 764.0585 Protein LSM14 homolog A OS=Homo sapiens OX=9606 GN=LSM14A PE=1 SV=3 6.47 3399.8 - 5.47E+06 - - - 2.8587 - 4.86 0.675 - 683.6 1 2 0 0.0065 23 0 0 0 4.50E+07 3.74E+07 - - - 9.7728 0.9996 221125_WJC_METTL3_EV_vs_WT_F05.20730.20730.4 1.76E-05 12/108 K.GLDVDSLVIEHIQVNK[136.11]APK[136.11].M "sp|P18621|RL17_HUMAN,tr|A0A087WWH0|A0A087WWH0_HUMAN,tr|J3QS96|J3QS96_HUMAN,tr|J3QLC8|J3QLC8_HUMAN,tr|J3QQT2|J3QQT2_HUMAN,tr|A0A0A0MRF8|A0A0A0MRF8_HUMAN,tr|J3KRB3|J3KRB3_HUMAN,tr|J3KRX5|J3KRX5_HUMAN,tr|A0A087WXM6|A0A087WXM6_HUMAN,tr|A0A0A6YYL6|A0A0A6YYL6_HUMAN" 10 2090.1707 0.99 71352 20730 4 2090.174686 523.5499 60S ribosomal protein L17 OS=Homo sapiens OX=9606 GN=RPL17 PE=1 SV=3 5.38 3400.8 - 219110 - - - 1.9286 - 2.084 0.456 - 77.3 1 2 1 0.004 19 0 0 0 1.21E+06 1.23E+06 - - - 3.4423 1 221125_WJC_METTL3_EV_vs_WT_F05.20734.20734.3 3.17E-13 19/84 K.NADMSEEMQQDSVEC[160.03]ATQALEK.Y "sp|P63167|DYL1_HUMAN,tr|F8VXI7|F8VXI7_HUMAN,tr|F8VXL2|F8VXL2_HUMAN,tr|F8VRV5|F8VRV5_HUMAN" 4 2513.0356 1.37 71354 20734 3 2513.036479 838.6858 "Dynein light chain 1, cytoplasmic OS=Homo sapiens OX=9606 GN=DYNLL1 PE=1 SV=1" 3.77 3401.4 - 700663 - - - 0.3422 - 3.593 0.782 - 541.7 1 2 0 0.0009 22 0 0 0 2.78E+07 2.02E+07 - - - 10.2906 0.9998 221125_WJC_METTL3_EV_vs_WT_F05.20736.20736.3 1.17E-05 Nov-44 R.AR[166.11]FEELC[160.03]SDLFR[166.11].S "sp|P48741|HSP77_HUMAN,sp|P0DMV8|HS71A_HUMAN,sp|P0DMV9|HS71B_HUMAN,sp|P17066|HSP76_HUMAN,tr|V9GZ37|V9GZ37_HUMAN,tr|A0A0G2JIW1|A0A0G2JIW1_HUMAN" 6 1561.7462 0.08 71356 20736 3 1561.748985 521.5893 Putative heat shock 70 kDa protein 7 OS=Homo sapiens OX=9606 GN=HSPA7 PE=5 SV=2 4.68 3401.7 - 401326 - - - 1.7813 - 2.386 0.506 - 245.6 1 2 1 0.0028 12 0 0 0 1.61E+06 1.92E+07 - - - 6.5911 1 221125_WJC_METTL3_EV_vs_WT_F05.20737.20737.2 3.58E-12 16/36 R.TATEEWGTEDWNEDLSETK.L "sp|Q14157|UBP2L_HUMAN,tr|Q5VU78|Q5VU78_HUMAN,tr|F8W726|F8W726_HUMAN,tr|Q5VU79|Q5VU79_HUMAN,tr|Q5VU77|Q5VU77_HUMAN" 5 2239.9393 2.17 71357 20737 2 2239.940775 1120.9769 Ubiquitin-associated protein 2-like OS=Homo sapiens OX=9606 GN=UBAP2L PE=1 SV=2 3.71 3401.8 - 388991 - - - 0.6509 - 3.712 0.785 - 902.8 1 2 0 0.0015 19 0 0 0 3.52E+07 1.63E+07 - - - 8.0631 1 221125_WJC_METTL3_EV_vs_WT_F05.20739.20739.3 3.65E-06 14/112 K.AVQGGGATPVVGAVQGPVPGMPPMTQAPR[166.11].L "sp|P09012|SNRPA_HUMAN,tr|M0QZG7|M0QZG7_HUMAN,tr|M0R268|M0R268_HUMAN" 3 2736.4079 0.73 71359 20739 3 2736.411676 913.1432 U1 small nuclear ribonucleoprotein A OS=Homo sapiens OX=9606 GN=SNRPA PE=1 SV=3 9.79 3402.1 - 180895 - - - 1.3817 - 2.633 0.557 - 100.6 1 2 0 0.0038 29 0 0 0 4.90E+06 6.71E+06 - - - 6.9763 0.9997 221125_WJC_METTL3_EV_vs_WT_F05.20744.20744.2 0.00684 16-Sep R.YLDVSILGK[136.11].F sp|Q86U44|MTA70_HUMAN 1 1014.5841 0.02 71362 20744 2 1014.58557 508.2993 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 5.83 3402.8 - 554944 - - - 1.4508 - 1.875 0.46 - 190.5 1 2 0 0.0015 9 0 0 0 2.90E+06 1.31E+08 - - - 4.2567 0.9961 221125_WJC_METTL3_EV_vs_WT_F05.20745.20745.3 2.23E-05 12/112 R.GQLASPSSQSAAASSLGPYGGAQPSASAL.S sp|Q96PK6|RBM14_HUMAN 1 2617.262 - 71363 20745 3 2617.265464 873.4279 RNA-binding protein 14 OS=Homo sapiens OX=9606 GN=RBM14 PE=1 SV=2 5.52 3402.9 - 415896 - - - 1.3277 - 2.638 0.52 - 101.8 1 1 0 0.0035 29 0 0 0 - - - - - 6.5682 1 221125_WJC_METTL3_EV_vs_WT_F05.20746.20746.4 8.42E-07 13/78 K.GHPFFEGVDWEHIR.E sp|Q9Y2H1|ST38L_HUMAN 1 1724.8059 4.18 71364 20746 4 1724.808691 432.2088 Serine\threonine-protein kinase 38-like OS=Homo sapiens OX=9606 GN=STK38L PE=1 SV=3 5.27 3403 - 410950 - - - 1.5955 - 2.584 0.503 - 125.9 1 2 0 0.0028 14 0 0 0 5.52E+06 1.32E+06 - - - 3.9489 1 221125_WJC_METTL3_EV_vs_WT_F05.20747.20747.4 8.62E-10 21/138 R.FSTFAGSITGPLYTHRPPITISSK.L "sp|P07197|NFM_HUMAN,tr|E7ESP9|E7ESP9_HUMAN,tr|E7EMV2|E7EMV2_HUMAN" 3 2577.3591 3.45 71365 20747 4 2577.36147 645.3471 Neurofilament medium polypeptide OS=Homo sapiens OX=9606 GN=NEFM PE=1 SV=3 9.99 3403.1 - 399544 - - - 0.9102 - 3.577 0.588 - 270 1 2 0 0.0023 24 0 0 0 2.07E+07 6.01E+06 - - - 4.7524 0.9982 221125_WJC_METTL3_EV_vs_WT_F05.20750.20750.2 9.88E-08 17/30 K.KDC[160.03]EVVMMIGLPGAGK.T "sp|Q00839|HNRPU_HUMAN,tr|A0A1W2PQL0|A0A1W2PQL0_HUMAN,tr|A0A1W2PPL4|A0A1W2PPL4_HUMAN,tr|A0A1W2PQ74|A0A1W2PQ74_HUMAN,tr|Q5RI18|Q5RI18_HUMAN,tr|A0A1W2PP35|A0A1W2PP35_HUMAN,tr|A0A1W2PPS1|A0A1W2PPS1_HUMAN,tr|A0A1W2PRZ7|A0A1W2PRZ7_HUMAN,tr|A0A1W2PPH7|A0A1W2PPH7_HUMAN,tr|A0A1W2PQD4|A0A1W2PQD4_HUMAN,tr|A0A1W2PP34|A0A1W2PP34_HUMAN,tr|A0A1X7SBS1|A0A1X7SBS1_HUMAN" 12 1703.8409 3.03 71368 20750 2 1703.847258 852.9277 Heterogeneous nuclear ribonucleoprotein U OS=Homo sapiens OX=9606 GN=HNRNPU PE=1 SV=6 6.06 3403.5 - 283046 - - - 3.7492 - 2.846 0.312 - 538.1 1 2 0 0.0064 16 0 0 0 7.25E+06 2.39E+06 - - - 3.9149 0.9997 221125_WJC_METTL3_EV_vs_WT_F05.20751.20751.3 4.71E-09 15/104 K.KEGPYDVVVLPGGNLGAQNLSESAAVK.E "sp|Q99497|PARK7_HUMAN,tr|K7EN27|K7EN27_HUMAN" 2 2711.413 6.35 71369 20751 3 2711.427801 904.8116 Parkinson disease protein 7 OS=Homo sapiens OX=9606 GN=PARK7 PE=1 SV=2 4.68 3403.7 - 240176 - - - 5.4551 - 2.995 0.63 - 176.3 1 2 0 0.0148 27 0 0 0 2.11E+06 3.33E+05 - - - 8.0835 0.9998 221125_WJC_METTL3_EV_vs_WT_F05.20752.20752.4 0.00166 11/138 R.FSTFAGSITGPLYTHR[166.11]PPITISSK[136.11].L "sp|P07197|NFM_HUMAN,tr|E7ESP9|E7ESP9_HUMAN,tr|E7EMV2|E7EMV2_HUMAN" 3 2595.3816 3.49 71370 20752 4 2595.38521 649.8527 Neurofilament medium polypeptide OS=Homo sapiens OX=9606 GN=NEFM PE=1 SV=3 9.99 3403.8 - 208367 - - - 1.3932 - 2.442 0.384 - 43.1 1 2 0 0.0036 24 0 0 0 2.05E+07 5.88E+06 - - - 2.8539 1 221125_WJC_METTL3_EV_vs_WT_F05.20756.20756.3 1.85E-10 16/72 R.TATEEWGTEDWNEDLSETK.L "sp|Q14157|UBP2L_HUMAN,tr|Q5VU78|Q5VU78_HUMAN,tr|F8W726|F8W726_HUMAN,tr|Q5VU79|Q5VU79_HUMAN,tr|Q5VU77|Q5VU77_HUMAN" 5 2239.9393 1.9 71372 20756 3 2239.94375 747.6537 Ubiquitin-associated protein 2-like OS=Homo sapiens OX=9606 GN=UBAP2L PE=1 SV=2 3.71 3404.3 - 2.04E+06 - - - 1.9791 - 3.263 0.664 - 224.1 1 2 0 0.0044 19 0 0 0 2.84E+07 1.49E+07 - - - 8.8472 1 221125_WJC_METTL3_EV_vs_WT_F05.20757.20757.2 2.27E-11 17/36 R.TATEEWGTEDWNEDLSETK[136.11].L "sp|Q14157|UBP2L_HUMAN,tr|Q5VU78|Q5VU78_HUMAN,tr|F8W726|F8W726_HUMAN,tr|Q5VU79|Q5VU79_HUMAN,tr|Q5VU77|Q5VU77_HUMAN" 5 2247.9535 2.17 71373 20757 2 2247.955139 1124.984 Ubiquitin-associated protein 2-like OS=Homo sapiens OX=9606 GN=UBAP2L PE=1 SV=2 3.71 3404.5 - 918615 - - - 0.7215 - 3.8 0.754 - 1018.8 1 2 0 0.0016 19 0 0 0 3.52E+07 1.63E+07 - - - 7.8917 0.9956 221125_WJC_METTL3_EV_vs_WT_F05.20758.20758.3 7.08E-05 19/72 K.ISSIQSIVPALEIANAHRK.P "sp|P10809|CH60_HUMAN,tr|A0A7I2V2X6|A0A7I2V2X6_HUMAN,tr|A0A7I2YQK6|A0A7I2YQK6_HUMAN,tr|A0A7I2V599|A0A7I2V599_HUMAN,tr|A0A7I2YQ71|A0A7I2YQ71_HUMAN,tr|A0A7I2V5M1|A0A7I2V5M1_HUMAN,tr|A0A7I2V5K3|A0A7I2V5K3_HUMAN,tr|A0A7I2V369|A0A7I2V369_HUMAN" 8 2046.1586 1.31 71374 20758 3 2046.161628 683.0601 "60 kDa heat shock protein, mitochondrial OS=Homo sapiens OX=9606 GN=HSPD1 PE=1 SV=2" 8.75 3404.6 - 596228 - - - 1.493 - 3.025 0.473 - 340 1 1 0 0.0031 19 0 0 0 4.17E+07 3.17E+07 - - - 6.5321 0.9912 221125_WJC_METTL3_EV_vs_WT_F05.20759.20759.3 0.00164 14/72 K.ISSIQSIVPALEIANAHR[166.11]K[136.11].P "sp|P10809|CH60_HUMAN,tr|A0A7I2V2X6|A0A7I2V2X6_HUMAN,tr|A0A7I2YQK6|A0A7I2YQK6_HUMAN,tr|A0A7I2V599|A0A7I2V599_HUMAN,tr|A0A7I2YQ71|A0A7I2YQ71_HUMAN,tr|A0A7I2V5M1|A0A7I2V5M1_HUMAN,tr|A0A7I2V5K3|A0A7I2V5K3_HUMAN,tr|A0A7I2V369|A0A7I2V369_HUMAN" 8 2064.181 1.31 71375 20759 3 2064.182966 689.0676 "60 kDa heat shock protein, mitochondrial OS=Homo sapiens OX=9606 GN=HSPD1 PE=1 SV=2" 8.75 3404.7 - 534100 - - - 0.9316 - 2.38 0.427 - 161.6 1 1 0 0.0019 19 0 0 0 4.14E+07 3.16E+07 - - - 5.4304 0.9999 221125_WJC_METTL3_EV_vs_WT_F05.20768.20768.3 2.67E-08 15/80 R.NELMQSLNQDSNSNFK[136.11]DTLLK[136.11].E "sp|Q15643|TRIPB_HUMAN,tr|H0YJ97|H0YJ97_HUMAN" 2 2454.2032 1.87 71382 20768 3 2454.205663 819.075 Thyroid receptor-interacting protein 11 OS=Homo sapiens OX=9606 GN=TRIP11 PE=1 SV=3 4.56 3405.9 - 515153 - - - 1.0227 - 3.032 0.579 - 208.4 1 2 1 0.0025 21 0 0 0 5.77E+06 3.09E+06 - - - 7.6539 1 221125_WJC_METTL3_EV_vs_WT_F05.20777.20777.4 3.55E-09 36/162 K.AIGSSPLGSGEGLLGLSPGPNGHSHLLK.V "sp|Q8IY67|RAVR1_HUMAN,tr|K7EQG2|K7EQG2_HUMAN,tr|E9PAU2|E9PAU2_HUMAN,tr|A0A087WZ13|A0A087WZ13_HUMAN" 4 2651.4031 1.06 71389 20777 4 2651.409778 663.8581 Ribonucleoprotein PTB-binding 1 OS=Homo sapiens OX=9606 GN=RAVER1 PE=1 SV=1 6.96 3407.1 - 6.64E+06 - - - 2.5134 - 4.358 0.591 - 626.4 1 2 0 0.0067 28 0 0 0 9.73E+07 9.17E+07 - - - 4.8252 1 221125_WJC_METTL3_EV_vs_WT_F05.20778.20778.4 6.99E-11 26/162 K.AIGSSPLGSGEGLLGLSPGPNGHSHLLK[136.11].V "sp|Q8IY67|RAVR1_HUMAN,tr|K7EQG2|K7EQG2_HUMAN,tr|E9PAU2|E9PAU2_HUMAN,tr|A0A087WZ13|A0A087WZ13_HUMAN" 4 2659.4173 1.06 71390 20778 4 2659.422116 665.8616 Ribonucleoprotein PTB-binding 1 OS=Homo sapiens OX=9606 GN=RAVER1 PE=1 SV=1 6.96 3407.2 - 6.25E+06 - - - 1.8057 - 5.052 0.596 - 266 1 2 0 0.0048 28 0 0 0 9.74E+07 9.17E+07 - - - 4.9152 1 221125_WJC_METTL3_EV_vs_WT_F05.20779.20779.3 0.000514 24/108 K.AIGSSPLGSGEGLLGLSPGPNGHSHLLK[136.11].V "sp|Q8IY67|RAVR1_HUMAN,tr|K7EQG2|K7EQG2_HUMAN,tr|E9PAU2|E9PAU2_HUMAN,tr|A0A087WZ13|A0A087WZ13_HUMAN" 4 2659.4173 1.03 71391 20779 3 2659.418698 887.4797 Ribonucleoprotein PTB-binding 1 OS=Homo sapiens OX=9606 GN=RAVER1 PE=1 SV=1 6.96 3407.3 - 695700 - - - 0.5204 - 4.729 0.563 - 433.1 1 2 0 0.0014 28 0 0 0 1.01E+07 9.80E+06 - - - 8.391 0.9986 221125_WJC_METTL3_EV_vs_WT_F05.20780.20780.3 2.24E-12 22/100 R.TNALTVQQLTAAQQQQYALAAAQQPH.L "sp|Q8TB72|PUM2_HUMAN,tr|A0A0C4DG68|A0A0C4DG68_HUMAN,tr|C9JW01|C9JW01_HUMAN" 3 2792.4206 - 71392 20780 3 2792.423598 931.8141 Pumilio homolog 2 OS=Homo sapiens OX=9606 GN=PUM2 PE=1 SV=2 6.4 3407.4 - 644758 - - - 1.0897 - 3.824 0.569 - 457.8 1 1 0 0.003 26 0 0 0 - - - - - 7.9688 1 221125_WJC_METTL3_EV_vs_WT_F05.20781.20781.3 3.17E-08 29/108 K.AIGSSPLGSGEGLLGLSPGPNGHSHLLK.V "sp|Q8IY67|RAVR1_HUMAN,tr|K7EQG2|K7EQG2_HUMAN,tr|E9PAU2|E9PAU2_HUMAN,tr|A0A087WZ13|A0A087WZ13_HUMAN" 4 2651.4031 1.03 71393 20781 3 2651.410153 884.8083 Ribonucleoprotein PTB-binding 1 OS=Homo sapiens OX=9606 GN=RAVER1 PE=1 SV=1 6.96 3407.6 - 588341 - - - 2.6548 - 4.703 0.634 - 625.1 1 2 0 0.007 28 0 0 0 1.01E+07 9.80E+06 - - - 9.1684 0.9999 221125_WJC_METTL3_EV_vs_WT_F05.20782.20782.3 7.86E-07 13/80 R.NELMQSLNQDSNSNFKDTLLK.E "sp|Q15643|TRIPB_HUMAN,tr|H0YJ97|H0YJ97_HUMAN" 2 2438.1748 1.86 71394 20782 3 2438.175198 813.7322 Thyroid receptor-interacting protein 11 OS=Homo sapiens OX=9606 GN=TRIP11 PE=1 SV=3 4.56 3407.7 - 527035 - - - 0.1825 - 2.508 0.577 - 145.2 1 2 1 0.0004 21 0 0 0 6.17E+06 3.31E+06 - - - 7.1773 0.9995 221125_WJC_METTL3_EV_vs_WT_F05.20784.20784.4 0.000655 Nov-90 R.K[136.11]FDEVLVNHFC[160.03]EEFGK[136.11].K "sp|P34932|HSP74_HUMAN,tr|A0A087WTS8|A0A087WTS8_HUMAN,tr|A0A087WYC1|A0A087WYC1_HUMAN" 3 2012.9637 0.17 71396 20784 4 2012.964327 504.2482 Heat shock 70 kDa protein 4 OS=Homo sapiens OX=9606 GN=HSPA4 PE=1 SV=4 4.83 3408 - 272260 - - - 0.312 - 1.701 0.343 - 65.2 1 2 0 0.0006 16 0 0 0 7.77E+05 4.70E+06 - - - 2.3984 0.9999 221125_WJC_METTL3_EV_vs_WT_F05.20785.20785.3 0.000292 Dec-56 R.QYYTLLNQAPDMLHR[166.11].F "sp|Q13283|G3BP1_HUMAN,tr|E5RH00|E5RH00_HUMAN,tr|E5RH42|E5RH42_HUMAN,tr|A0A7I2V4Y8|A0A7I2V4Y8_HUMAN,tr|A0A7I2V3C4|A0A7I2V3C4_HUMAN,tr|A0A7P0P2U7|A0A7P0P2U7_HUMAN,tr|A0A7I2V2S5|A0A7I2V2S5_HUMAN,tr|A0A7I2YQU8|A0A7I2YQU8_HUMAN,tr|E5RJU8|E5RJU8_HUMAN,tr|A0A7I2V651|A0A7I2V651_HUMAN,tr|E5RIF8|E5RIF8_HUMAN,tr|A0A7I2YQN9|A0A7I2YQN9_HUMAN" 12 1871.9228 1.02 71397 20785 3 1871.923053 624.9815 Ras GTPase-activating protein-binding protein 1 OS=Homo sapiens OX=9606 GN=G3BP1 PE=1 SV=1 6.74 3408.1 - 260721 - - - 0.1496 - 1.858 0.423 - 149.7 1 2 0 0.0003 15 0 0 0 3.76E+06 3.70E+06 - - - 4.8725 1 221125_WJC_METTL3_EV_vs_WT_F05.20786.20786.3 2.25E-07 18/112 K.AVQGGGATPVVGAVQGPVPGMPPMTQAPR.L "sp|P09012|SNRPA_HUMAN,tr|M0QZG7|M0QZG7_HUMAN,tr|M0R268|M0R268_HUMAN" 3 2726.3996 0.66 71398 20786 3 2726.404084 909.8072 U1 small nuclear ribonucleoprotein A OS=Homo sapiens OX=9606 GN=SNRPA PE=1 SV=3 9.79 3408.2 - 260191 - - - 1.6355 - 2.732 0.542 - 157.5 1 2 0 0.0045 29 0 0 0 4.96E+06 7.54E+06 - - - 6.8937 1 221125_WJC_METTL3_EV_vs_WT_F05.20792.20792.3 5.02E-07 15/104 R.TLYDAELSQMQSHISDTSVVLSMDNNR.S sp|P12035|K2C3_HUMAN 1 3053.407 999 71402 20792 3 3053.412892 1018.8096 "Keratin, type II cytoskeletal 3 OS=Homo sapiens OX=9606 GN=KRT3 PE=1 SV=3" 4.22 3409 - 763010 - - - 1.9247 - 3.03 0.597 - 221 1 2 0 0.0059 27 0 0 0 2.30E+07 0.00E+00 - - - 7.7447 0.9999 221125_WJC_METTL3_EV_vs_WT_F05.20796.20796.4 4.38E-06 17/108 K.IKENKPLPPVPIPNLVGIR.G sp|O60476|MA1A2_HUMAN 1 2093.2725 1.59 71406 20796 4 2093.277284 524.3254 "Mannosyl-oligosaccharide 1,2-alpha-mannosidase IB OS=Homo sapiens OX=9606 GN=MAN1A2 PE=1 SV=1" 9.99 3409.5 - 294042 - - - 2.2945 - 3.057 0.595 - 240 1 2 1 0.0048 19 0 0 0 1.29E+07 8.12E+06 - - - 4.7816 0.9989 221125_WJC_METTL3_EV_vs_WT_F05.20797.20797.3 4.53E-06 12/104 K.AAQGPPAPAVPPNTDVMAC[160.03]TQTALLQK[136.11].L "sp|O60232|ZNRD2_HUMAN,tr|H0YEB6|H0YEB6_HUMAN,tr|G3V1B8|G3V1B8_HUMAN" 3 2754.3924 0.24 71407 20797 3 2754.409523 919.1381 Protein ZNRD2 OS=Homo sapiens OX=9606 GN=ZNRD2 PE=1 SV=1 5.87 3409.7 - 162226 - - - 6.209 - 2.331 0.537 - 92.4 1 2 0 0.0171 27 0 0 0 4.82E+05 2.05E+06 - - - 6.4693 0.9997 221125_WJC_METTL3_EV_vs_WT_F05.20802.20802.3 1.14E-05 Dec-88 K.SPTMEQAVQTASAHLPAPAAVGR[166.11].R sp|Q8ND56|LS14A_HUMAN 1 2299.1618 1.21 71410 20802 3 2299.169666 767.3946 Protein LSM14 homolog A OS=Homo sapiens OX=9606 GN=LSM14A PE=1 SV=3 6.47 3410.4 - 189057 - - - 3.4065 - 2.215 0.47 - 67 1 2 0 0.0078 23 0 0 0 4.50E+07 3.73E+07 - - - 5.6435 0.9997 221125_WJC_METTL3_EV_vs_WT_F05.20803.20803.3 1.03E-05 Nov-72 R.DQPAFTPSGILTPHALGSR[166.11].N sp|Q9H0D6|XRN2_HUMAN 1 1974.0198 1.1 71411 20803 3 1974.025861 659.0139 5'-3' exoribonuclease 2 OS=Homo sapiens OX=9606 GN=XRN2 PE=1 SV=1 6.74 3410.5 - 302515 - - - 3.0476 - 2.545 0.403 - 105.3 1 2 0 0.006 19 0 0 0 3.75E+07 3.41E+07 - - - 5.3264 0.9998 221125_WJC_METTL3_EV_vs_WT_F05.20804.20804.4 0.000695 11/108 K.IK[136.11]ENK[136.11]PLPPVPIPNLVGIR[166.11].G sp|O60476|MA1A2_HUMAN 1 2119.3092 1.57 71412 20804 4 2119.312978 530.8346 "Mannosyl-oligosaccharide 1,2-alpha-mannosidase IB OS=Homo sapiens OX=9606 GN=MAN1A2 PE=1 SV=1" 9.99 3410.6 - 246638 - - - 1.8058 - 2.322 0.527 - 78.6 1 2 1 0.0038 19 0 0 0 1.35E+07 8.62E+06 - - - 4.0969 1 221125_WJC_METTL3_EV_vs_WT_F05.20806.20806.2 7.60E-10 13/30 Y.SDNQPGVLIQVYEGER[166.11].A "sp|P0DMV8|HS71A_HUMAN,sp|P34931|HS71L_HUMAN,sp|P11142|HSP7C_HUMAN,sp|P0DMV9|HS71B_HUMAN,tr|E9PNE6|E9PNE6_HUMAN,tr|A8K7Q2|A8K7Q2_HUMAN,tr|E9PKE3|E9PKE3_HUMAN,tr|E9PS65|E9PS65_HUMAN,tr|Q53FA3|Q53FA3_HUMAN,tr|V9GZ37|V9GZ37_HUMAN,tr|A0A0G2JIW1|A0A0G2JIW1_HUMAN" 11 1812.8882 0.23 71414 20806 2 1812.893343 907.4514 Heat shock 70 kDa protein 1A OS=Homo sapiens OX=9606 GN=HSPA1A PE=1 SV=1 4.14 3410.9 - 201115 - - - 2.8579 - 2.787 0.689 - 425.9 1 1 0 0.0052 16 0 0 0 1.03E+06 4.41E+06 - - - 6.6483 1 221125_WJC_METTL3_EV_vs_WT_F05.20809.20809.4 7.74E-06 10/102 K.VC[160.03]IESEHSMDTLLATLKK.T "sp|O00244|ATOX1_HUMAN,tr|E5RGN3|E5RGN3_HUMAN,tr|E5RIM7|E5RIM7_HUMAN" 3 2074.0439 1.38 71415 20809 4 2074.045043 519.5182 Copper transport protein ATOX1 OS=Homo sapiens OX=9606 GN=ATOX1 PE=1 SV=1 5.44 3411.3 - 380209 - - - 0.5689 - 1.638 0.507 - 34.5 1 2 0 0.0012 18 0 0 0 4.53E+06 3.27E+06 - - - 3.8076 0.9999 221125_WJC_METTL3_EV_vs_WT_F05.20810.20810.3 2.96E-07 Nov-60 K.K[136.11]VSQEILELLNTTTAK[136.11].E "sp|Q86U44|MTA70_HUMAN,tr|H0YFV6|H0YFV6_HUMAN" 2 1803.0324 0 71416 20810 3 1803.036039 602.0181 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 6.14 3411.4 - 218468 - - - 2.0016 - 2.385 0.485 - 139.6 1 2 0 0.0036 16 0 0 0 2.36E+04 1.45E+07 - - - 6.1765 0.9999 221125_WJC_METTL3_EV_vs_WT_F05.20811.20811.3 7.32E-07 19/72 R.DQPAFTPSGILTPHALGSR.N sp|Q9H0D6|XRN2_HUMAN 1 1964.0116 1.1 71417 20811 3 1964.017823 655.6778 5'-3' exoribonuclease 2 OS=Homo sapiens OX=9606 GN=XRN2 PE=1 SV=1 6.74 3411.6 - 391835 - - - 3.1812 - 3.305 0.561 - 444.5 1 2 0 0.0062 19 0 0 0 3.74E+07 3.40E+07 - - - 7.7298 0.9999 221125_WJC_METTL3_EV_vs_WT_F05.20812.20812.3 3.01E-05 Nov-72 K.QASDYGINHAQLPLGNFVK[136.11].M sp|Q8TBZ6|TM10A_HUMAN 1 2079.0629 0.68 71418 20812 3 2079.066392 694.0282 tRNA methyltransferase 10 homolog A OS=Homo sapiens OX=9606 GN=TRMT10A PE=1 SV=1 6.74 3411.7 - 301573 - - - 1.6849 - 2.277 0.453 - 98.5 1 2 0 0.0035 19 0 0 0 4.05E+06 5.93E+06 - - - 5.6111 1 221125_WJC_METTL3_EV_vs_WT_F05.20821.20821.3 1.57E-07 16/56 K.KQELEVLTANIQDLK.E "sp|Q9HBM1|SPC25_HUMAN,tr|C9JW94|C9JW94_HUMAN" 2 1740.9622 2.9 71425 20821 3 1740.964892 581.328 Kinetochore protein Spc25 OS=Homo sapiens OX=9606 GN=SPC25 PE=1 SV=1 4.68 3412.9 - 908752 - - - 1.5664 - 3.353 0.448 - 518.1 1 2 0 0.0027 15 0 0 0 1.67E+07 5.75E+06 - - - 6.691 1 221125_WJC_METTL3_EV_vs_WT_F05.20822.20822.3 7.69E-09 16/56 R.GFAFVTFDDHDSVDK.L "sp|Q32P51|RA1L2_HUMAN,sp|P09651|ROA1_HUMAN,tr|A0A7I2YQX9|A0A7I2YQX9_HUMAN,tr|F8VZ49|F8VZ49_HUMAN,tr|A0A7I2V3R8|A0A7I2V3R8_HUMAN,tr|F8VTQ5|F8VTQ5_HUMAN,tr|F8W6I7|F8W6I7_HUMAN,tr|H0YH80|H0YH80_HUMAN,tr|A0A7I2V2L6|A0A7I2V2L6_HUMAN,tr|A0A7I2V3W0|A0A7I2V3W0_HUMAN,tr|A0A7I2V5U9|A0A7I2V5U9_HUMAN,tr|A0A2R8Y4L2|A0A2R8Y4L2_HUMAN" 12 1698.7526 1.34 71426 20822 3 1698.756504 567.2581 Heterogeneous nuclear ribonucleoprotein A1-like 2 OS=Homo sapiens OX=9606 GN=HNRNPA1L2 PE=2 SV=2 4.13 3413 - 484375 - - - 2.3182 - 3.107 0.643 - 209.2 1 2 0 0.0039 15 0 0 0 1.31E+07 9.80E+06 - - - 8.6659 1 221125_WJC_METTL3_EV_vs_WT_F05.20824.20824.3 5.57E-11 14/56 R.GFAFVTFDDHDSVDK[136.11].L "sp|Q32P51|RA1L2_HUMAN,sp|P09651|ROA1_HUMAN,tr|A0A7I2YQX9|A0A7I2YQX9_HUMAN,tr|F8VZ49|F8VZ49_HUMAN,tr|A0A7I2V3R8|A0A7I2V3R8_HUMAN,tr|F8VTQ5|F8VTQ5_HUMAN,tr|F8W6I7|F8W6I7_HUMAN,tr|H0YH80|H0YH80_HUMAN,tr|A0A7I2V2L6|A0A7I2V2L6_HUMAN,tr|A0A7I2V3W0|A0A7I2V3W0_HUMAN,tr|A0A7I2V5U9|A0A7I2V5U9_HUMAN,tr|A0A2R8Y4L2|A0A2R8Y4L2_HUMAN" 12 1706.7668 1.34 71428 20824 3 1706.772484 569.9295 Heterogeneous nuclear ribonucleoprotein A1-like 2 OS=Homo sapiens OX=9606 GN=HNRNPA1L2 PE=2 SV=2 4.13 3413.3 - 419948 - - - 3.3502 - 3.002 0.662 - 153.7 1 2 0 0.0057 15 0 0 0 1.32E+07 9.80E+06 - - - 8.7875 0.9803 221125_WJC_METTL3_EV_vs_WT_F05.20825.20825.3 0.0035 Sep-84 F.SATFDYQQAFGNSTGGFDGQAR[166.11].Q sp|Q96PK6|RBM14_HUMAN 1 2334.0177 1.18 71429 20825 3 2334.024539 779.0132 RNA-binding protein 14 OS=Homo sapiens OX=9606 GN=RBM14 PE=1 SV=2 4.21 3413.4 - 238078 - - - 2.9417 - 2.02 0.508 - 76.8 1 1 0 0.0069 22 0 0 0 2.81E+06 2.38E+06 - - - 5.8687 0.9705 221125_WJC_METTL3_EV_vs_WT_F05.20834.20834.2 1.24E-05 26-Sep R.GLLQDDAHPTLVTY.A "sp|Q86U44|MTA70_HUMAN,tr|F5H6D8|F5H6D8_HUMAN,tr|H0YFV6|H0YFV6_HUMAN,tr|B4DTN4|B4DTN4_HUMAN" 4 1541.7726 - 71436 20834 2 1541.776274 771.8936 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 4.2 3414.6 - 508727 - - - 2.4005 - 1.963 0.487 - 208.2 1 1 0 0.0037 14 0 0 0 - - - - - 4.3294 0.9999 221125_WJC_METTL3_EV_vs_WT_F05.20835.20835.3 3.09E-05 Nov-60 K.AQDGSHPLSLQDLIEK.V "sp|O94979|SC31A_HUMAN,tr|H0Y9K1|H0Y9K1_HUMAN,tr|H7BXG7|H7BXG7_HUMAN,tr|D6RHZ5|D6RHZ5_HUMAN,tr|D6REX3|D6REX3_HUMAN,tr|H0YAB3|H0YAB3_HUMAN" 6 1749.8897 1.39 71437 20835 3 1749.8915 584.3039 Protein transport protein Sec31A OS=Homo sapiens OX=9606 GN=SEC31A PE=1 SV=3 4.54 3414.8 - 435339 - - - 1.0126 - 2.261 0.393 - 187.3 1 2 0 0.0018 16 0 0 0 5.07E+06 3.65E+06 - - - 5.0143 0.9994 221125_WJC_METTL3_EV_vs_WT_F05.20836.20836.3 1.06E-06 14/56 K.K[136.11]QELEVLTANIQDLK[136.11].E "sp|Q9HBM1|SPC25_HUMAN,tr|C9JW94|C9JW94_HUMAN" 2 1756.9906 2.9 71438 20836 3 1756.994443 586.6708 Kinetochore protein Spc25 OS=Homo sapiens OX=9606 GN=SPC25 PE=1 SV=1 4.68 3414.9 - 419257 - - - 2.2072 - 3.017 0.256 - 308.2 1 2 0 0.0039 15 0 0 0 1.67E+07 5.75E+06 - - - 4.2745 1 221125_WJC_METTL3_EV_vs_WT_F05.20838.20838.3 6.23E-08 16/80 K.QQQDFSASSTTILDEEPIVNR.G sp|O43290|SNUT1_HUMAN 1 2377.1397 1.62 71440 20838 3 2377.144175 793.3872 U4\U6.U5 tri-snRNP-associated protein 1 OS=Homo sapiens OX=9606 GN=SART1 PE=1 SV=1 3.92 3415.1 - 229675 - - - 1.8623 - 2.904 0.6 - 239.8 1 2 0 0.0044 21 0 0 0 2.50E+06 1.55E+06 - - - 7.7841 1 221125_WJC_METTL3_EV_vs_WT_F05.20846.20846.3 8.58E-11 15/80 K.QQVQVVGLQEHLVNSADDVIK.M sp|Q99661|KIF2C_HUMAN 1 2318.223 1.13 71446 20846 3 2318.22678 773.7483 Kinesin-like protein KIF2C OS=Homo sapiens OX=9606 GN=KIF2C PE=1 SV=2 4.54 3416.2 - 498797 - - - 1.6202 - 3.264 0.605 - 220.3 1 2 0 0.0038 21 0 0 0 4.59E+06 4.06E+06 - - - 8.1202 0.9999 221125_WJC_METTL3_EV_vs_WT_F05.20849.20849.4 6.50E-09 17/96 K.FK[136.11]EISFAYEVLSNPEK[136.11]R[166.11].E sp|O60884|DNJA2_HUMAN 1 2082.0996 0.41 71449 20849 4 2082.099113 521.5322 DnaJ homolog subfamily A member 2 OS=Homo sapiens OX=9606 GN=DNAJA2 PE=1 SV=1 6.23 3416.6 - 241080 - - - -0.2397 - 3.326 0.595 - 279 1 2 1 -0.0005 17 0 0 0 8.71E+05 2.11E+06 - - - 4.822 1 221125_WJC_METTL3_EV_vs_WT_F05.20858.20858.2 2.31E-12 14/28 R.NNQGTVNWSVDDIVK[136.11].G "sp|P52292|IMA1_HUMAN,tr|J3QLL0|J3QLL0_HUMAN,tr|J3KS65|J3KS65_HUMAN,tr|A0A7I2V3Z3|A0A7I2V3Z3_HUMAN,tr|A0A7I2YQE1|A0A7I2YQE1_HUMAN,tr|A0A7I2V487|A0A7I2V487_HUMAN,tr|A0A7I2V351|A0A7I2V351_HUMAN" 7 1695.8308 1.2 71456 20858 2 1695.83376 848.9227 Importin subunit alpha-1 OS=Homo sapiens OX=9606 GN=KPNA2 PE=1 SV=1 4.21 3417.7 - 1.16E+06 - - - 1.7673 - 3.212 0.693 - 913.8 1 2 0 0.003 15 0 0 0 1.77E+07 1.48E+07 - - - 7.0274 0.9999 221125_WJC_METTL3_EV_vs_WT_F05.20861.20861.3 3.46E-05 18/68 R.QYQATGFLWEQYSDR[166.11]DGR[166.11].G "sp|Q13724|MOGS_HUMAN,tr|A0A3B3IRK6|A0A3B3IRK6_HUMAN,tr|A0A3B3IRW2|A0A3B3IRW2_HUMAN" 3 2239.0197 0.61 71459 20861 3 2239.022529 747.3472 Mannosyl-oligosaccharide glucosidase OS=Homo sapiens OX=9606 GN=MOGS PE=1 SV=5 4.56 3418.1 - 392541 - - - 1.2479 - 2.739 0.518 - 451.6 1 2 1 0.0028 18 0 0 0 2.53E+06 4.13E+06 - - - 6.8234 0.9996 221125_WJC_METTL3_EV_vs_WT_F05.20865.20865.3 3.02E-06 15/68 R.QYQATGFLWEQYSDRDGR.G "sp|Q13724|MOGS_HUMAN,tr|A0A3B3IRK6|A0A3B3IRK6_HUMAN,tr|A0A3B3IRW2|A0A3B3IRW2_HUMAN" 3 2219.0032 0.55 71463 20865 3 2218.99693 740.675 Mannosyl-oligosaccharide glucosidase OS=Homo sapiens OX=9606 GN=MOGS PE=1 SV=5 4.56 3418.6 - 227746 - - - -2.8233 - 2.636 0.527 - 296.6 1 2 1 -0.0063 18 0 0 0 2.29E+06 4.13E+06 - - - 6.8274 1 221125_WJC_METTL3_EV_vs_WT_F05.20871.20871.2 8.17E-12 15/28 R.NNQGTVNWSVDDIVK.G "sp|P52292|IMA1_HUMAN,tr|J3QLL0|J3QLL0_HUMAN,tr|J3KS65|J3KS65_HUMAN,tr|A0A7I2V3Z3|A0A7I2V3Z3_HUMAN,tr|A0A7I2YQE1|A0A7I2YQE1_HUMAN,tr|A0A7I2V487|A0A7I2V487_HUMAN,tr|A0A7I2V351|A0A7I2V351_HUMAN" 7 1687.8166 1.2 71467 20871 2 1687.818568 844.9156 Importin subunit alpha-1 OS=Homo sapiens OX=9606 GN=KPNA2 PE=1 SV=1 4.21 3419.3 - 1.58E+06 - - - 1.1879 - 3.303 0.675 - 994.8 1 2 0 0.002 15 0 0 0 1.77E+07 1.48E+07 - - - 6.9635 0.9996 221125_WJC_METTL3_EV_vs_WT_F05.20872.20872.4 0.000639 19/174 R.TVPAVAAHPLIAPAYAQLQPHQLLPQPSSK.H "sp|Q8IXK0|PHC2_HUMAN,tr|A0A0A0MSI2|A0A0A0MSI2_HUMAN" 2 3142.7291 0.76 71468 20872 4 3142.736062 786.6896 Polyhomeotic-like protein 2 OS=Homo sapiens OX=9606 GN=PHC2 PE=1 SV=1 8.31 3419.4 - 376681 - - - 2.2025 - 2.652 0.379 - 153.2 1 2 0 0.0069 30 0 0 0 5.91E+06 7.80E+06 - - - 2.8214 1 221125_WJC_METTL3_EV_vs_WT_F05.20873.20873.4 2.19E-11 20/114 K.SLNPNLLAVVTESTDAHHER[166.11].T sp|Q8N766|EMC1_HUMAN 1 2212.1112 1.22 71469 20873 4 2212.116786 554.0351 ER membrane protein complex subunit 1 OS=Homo sapiens OX=9606 GN=EMC1 PE=1 SV=1 5.26 3419.6 - 302013 - - - 2.5347 - 3.799 0.657 - 297.9 1 2 0 0.0056 20 0 0 0 2.10E+07 1.72E+07 - - - 5.3892 0.9999 221125_WJC_METTL3_EV_vs_WT_F05.20875.20875.3 0.000274 11/112 R.TAPTSTIAPGVVMASSPALPTQPAEEAAR.K "sp|P16220|CREB1_HUMAN,tr|C9JBT4|C9JBT4_HUMAN,tr|H7C1R5|H7C1R5_HUMAN,tr|C9J896|C9J896_HUMAN" 4 2820.4328 0.58 71471 20875 3 2820.433121 941.1515 Cyclic AMP-responsive element-binding protein 1 OS=Homo sapiens OX=9606 GN=CREB1 PE=1 SV=3 4.53 3419.8 - 109628 - - - 0.1283 - 2.068 0.436 - 58.2 1 2 0 0.0004 29 0 0 0 1.50E+06 2.59E+06 - - - 5.0725 0.9998 221125_WJC_METTL3_EV_vs_WT_F05.20876.20876.2 3.49E-10 13/28 R.DEGAVISQISDISNR[166.11].D "sp|O75410|TACC1_HUMAN,tr|E7EVI4|E7EVI4_HUMAN,tr|E5RFM9|E5RFM9_HUMAN,tr|A0A0C4DGD5|A0A0C4DGD5_HUMAN,tr|R4GMT7|R4GMT7_HUMAN,tr|H0YAY0|H0YAY0_HUMAN,tr|A0A0C4DGD3|A0A0C4DGD3_HUMAN,tr|H0YBT8|H0YBT8_HUMAN,tr|E7ET87|E7ET87_HUMAN" 9 1612.7932 1.02 71472 20876 2 1612.796821 807.4039 Transforming acidic coiled-coil-containing protein 1 OS=Homo sapiens OX=9606 GN=TACC1 PE=1 SV=2 4.03 3419.9 - 106277 - - - 2.2458 - 2.862 0.533 - 658.3 1 2 0 0.0036 15 0 0 0 3.10E+06 3.04E+06 - - - 5.5618 1 221125_WJC_METTL3_EV_vs_WT_F05.20886.20886.4 7.77E-13 19/114 K.SLNPNLLAVVTESTDAHHER.T sp|Q8N766|EMC1_HUMAN 1 2202.1029 1.22 71480 20886 4 2202.111374 551.533 ER membrane protein complex subunit 1 OS=Homo sapiens OX=9606 GN=EMC1 PE=1 SV=1 5.26 3421.3 - 287462 - - - 3.8441 - 4.104 0.686 - 266.9 1 2 0 0.0085 20 0 0 0 2.10E+07 1.72E+07 - - - 5.6666 1 221125_WJC_METTL3_EV_vs_WT_F05.20888.20888.2 1.24E-08 15/28 R.DEGAVISQISDISNR.D "sp|O75410|TACC1_HUMAN,tr|E7EVI4|E7EVI4_HUMAN,tr|E5RFM9|E5RFM9_HUMAN,tr|A0A0C4DGD5|A0A0C4DGD5_HUMAN,tr|R4GMT7|R4GMT7_HUMAN,tr|H0YAY0|H0YAY0_HUMAN,tr|A0A0C4DGD3|A0A0C4DGD3_HUMAN,tr|H0YBT8|H0YBT8_HUMAN,tr|E7ET87|E7ET87_HUMAN" 9 1602.7849 1.02 71482 20888 2 1602.790791 802.3997 Transforming acidic coiled-coil-containing protein 1 OS=Homo sapiens OX=9606 GN=TACC1 PE=1 SV=2 4.03 3421.6 - 198283 - - - 3.6574 - 3.301 0.639 - 886.3 1 2 0 0.0059 15 0 0 0 3.10E+06 3.04E+06 - - - 6.6949 1 221125_WJC_METTL3_EV_vs_WT_F05.20896.20896.3 6.38E-06 Oct-84 R.FELPMGTTEQPPLPQQTQPPAK.Q "sp|O95639|CPSF4_HUMAN,tr|H7C419|H7C419_HUMAN,tr|B7Z7B0|B7Z7B0_HUMAN,tr|C9JEV9|C9JEV9_HUMAN" 4 2434.2202 1.73 71488 20896 3 2434.225192 812.414 Cleavage and polyadenylation specificity factor subunit 4 OS=Homo sapiens OX=9606 GN=CPSF4 PE=1 SV=1 4.53 3422.7 - 238627 - - - 2.0315 - 2.265 0.592 - 90.2 1 2 0 0.0049 22 0 0 0 1.97E+07 1.14E+07 - - - 7.0772 0.9998 221125_WJC_METTL3_EV_vs_WT_F05.20897.20897.3 2.87E-05 14/60 K.QQEMMAALTDAIQDKK.N sp|Q92616|GCN1_HUMAN 1 1819.8808 0.87 71489 20897 3 1819.886297 607.6342 eIF-2-alpha kinase activator GCN1 OS=Homo sapiens OX=9606 GN=GCN1 PE=1 SV=6 4.56 3422.8 - 197151 - - - 3.0095 - 2.491 0.469 - 257.4 1 2 0 0.0055 16 0 0 0 2.59E+06 2.99E+06 - - - 6.1092 0.969 221125_WJC_METTL3_EV_vs_WT_F05.20900.20900.3 0.0468 May-96 K.EIENGVYLINGQVKDEDC[160.03]DLLEGQK.K sp|Q5SWX8|ODR4_HUMAN 1 2877.3702 1.08 71492 20900 3 2877.377311 960.1307 Protein odr-4 homolog OS=Homo sapiens OX=9606 GN=ODR4 PE=1 SV=1 3.95 3423.2 - 94472.8 - - - 2.4648 - 1.172 0.336 - 17.1 1 2 1 0.0071 25 0 0 0 4.65E+05 4.31E+05 - - - 2.6492 1 221125_WJC_METTL3_EV_vs_WT_F05.20904.20904.3 4.16E-14 26/104 R.GSSGGGC[160.03]FGGSSGGYGGLGGFGGGSFR.G "sp|P13645|K1C10_HUMAN,tr|A0A1B0GVI3|A0A1B0GVI3_HUMAN" 2 2341.9771 999 71494 20904 3 2341.982678 781.6663 "Keratin, type I cytoskeletal 10 OS=Homo sapiens OX=9606 GN=KRT10 PE=1 SV=6" 8.22 3423.8 - 974773 - - - 2.4001 - 4.499 0.749 - 374.3 1 2 0 0.0056 27 0 0 0 4.00E+08 0.00E+00 - - - 10.3489 1 221125_WJC_METTL3_EV_vs_WT_F05.20905.20905.3 5.06E-14 17/100 R.IGLNNSPVNGNSSC[160.03]QMAFPSSQSLYR.T sp|Q12948|FOXC1_HUMAN 1 2827.3018 3.89 71495 20905 3 2827.30861 943.4412 Forkhead box protein C1 OS=Homo sapiens OX=9606 GN=FOXC1 PE=1 SV=3 8.22 3423.9 - 323377 - - - 2.4221 - 3.31 0.696 - 166.4 1 2 0 0.0068 26 0 0 0 1.24E+07 3.20E+06 - - - 9.0516 0.9993 221125_WJC_METTL3_EV_vs_WT_F05.20906.20906.4 6.22E-12 23/168 R.VIQPTSGMIGSLSMHPELANAHNVIVTER.V sp|Q02413|DSG1_HUMAN 1 3100.5798 999 71496 20906 4 3100.600862 776.1522 Desmoglein-1 OS=Homo sapiens OX=9606 GN=DSG1 PE=1 SV=2 6 3424 - 593294 - - - 6.801 - 4.273 0.581 - 295.4 1 2 0 0.0211 29 0 0 0 6.73E+06 0.00E+00 - - - 4.7248 0.9999 221125_WJC_METTL3_EV_vs_WT_F05.20907.20907.3 1.62E-05 Dec-84 R.FELPMGTTEQPPLPQQTQPPAK[136.11].Q "sp|O95639|CPSF4_HUMAN,tr|H7C419|H7C419_HUMAN,tr|B7Z7B0|B7Z7B0_HUMAN,tr|C9JEV9|C9JEV9_HUMAN" 4 2442.2344 1.75 71497 20907 3 2442.241861 815.0854 Cleavage and polyadenylation specificity factor subunit 4 OS=Homo sapiens OX=9606 GN=CPSF4 PE=1 SV=1 4.53 3424.1 - 294904 - - - 3.0357 - 2.323 0.615 - 120.6 1 2 0 0.0074 22 0 0 0 1.98E+07 1.13E+07 - - - 7.3929 0.9996 221125_WJC_METTL3_EV_vs_WT_F05.20909.20909.3 0.000278 Sep-76 K.GHPDLQGQPAEEIFESVGDR.E sp|P49257|LMAN1_HUMAN 1 2180.0134 1.85 71499 20909 3 2180.01739 727.6784 Protein ERGIC-53 OS=Homo sapiens OX=9606 GN=LMAN1 PE=1 SV=2 4.17 3424.4 - 163833 - - - 1.8188 - 2.326 0.354 - 63.1 1 2 0 0.004 20 0 0 0 2.47E+06 1.34E+06 - - - 4.5336 0.9712 221125_WJC_METTL3_EV_vs_WT_F05.20911.20911.4 5.87E-06 21/108 K.ISSIQSIVPALEIANAHRK.P "sp|P10809|CH60_HUMAN,tr|A0A7I2V2X6|A0A7I2V2X6_HUMAN,tr|A0A7I2YQK6|A0A7I2YQK6_HUMAN,tr|A0A7I2V599|A0A7I2V599_HUMAN,tr|A0A7I2YQ71|A0A7I2YQ71_HUMAN,tr|A0A7I2V5M1|A0A7I2V5M1_HUMAN,tr|A0A7I2V5K3|A0A7I2V5K3_HUMAN,tr|A0A7I2V369|A0A7I2V369_HUMAN" 8 2046.1586 1.26 71500 20911 4 2046.16673 512.5469 "60 kDa heat shock protein, mitochondrial OS=Homo sapiens OX=9606 GN=HSPD1 PE=1 SV=2" 8.75 3424.6 - 2.42E+06 - - - 3.9865 - 3.3 0.484 - 330.3 1 1 0 0.0082 19 0 0 0 1.64E+08 1.30E+08 - - - 3.8404 0.9998 221125_WJC_METTL3_EV_vs_WT_F05.20913.20913.4 9.15E-07 17/114 R.FVHSENQHLVSPEALDFLDK.L "sp|P68400|CSK21_HUMAN,sp|Q8NEV1|CSK23_HUMAN,tr|A0A2R8YFU2|A0A2R8YFU2_HUMAN,tr|A0A2R8YD58|A0A2R8YD58_HUMAN,tr|A0A2R8YF43|A0A2R8YF43_HUMAN,tr|A0A2R8Y5A0|A0A2R8Y5A0_HUMAN,tr|A0A087WY74|A0A087WY74_HUMAN,tr|A0A2R8YDP2|A0A2R8YDP2_HUMAN,tr|E7EU96|E7EU96_HUMAN" 9 2324.1437 1.12 71501 20913 4 2324.153554 582.0432 Casein kinase II subunit alpha OS=Homo sapiens OX=9606 GN=CSNK2A1 PE=1 SV=1 4.72 3424.9 - 838420 - - - 4.2351 - 3.166 0.516 - 209.1 1 2 0 0.0098 20 0 0 0 1.73E+07 1.55E+07 - - - 4.0998 1 221125_WJC_METTL3_EV_vs_WT_F05.20915.20915.2 1.56E-16 22/52 R.GSSGGGC[160.03]FGGSSGGYGGLGGFGGGSFR.G "sp|P13645|K1C10_HUMAN,tr|A0A1B0GVI3|A0A1B0GVI3_HUMAN" 2 2341.9771 999 71503 20915 2 2341.981553 1171.9958 "Keratin, type I cytoskeletal 10 OS=Homo sapiens OX=9606 GN=KRT10 PE=1 SV=6" 8.22 3425.1 - 299817 - - - 1.9197 - 4.329 0.807 - 1245.5 1 2 0 0.0045 27 0 0 0 7.24E+07 0.00E+00 - - - 8.6027 0.9999 221125_WJC_METTL3_EV_vs_WT_F05.20918.20918.3 2.89E-08 Nov-56 R.GFAFVTFDDHDTVDK[136.11].L "sp|P51991|ROA3_HUMAN,tr|A0A7I2V5D8|A0A7I2V5D8_HUMAN,tr|A0A7I2V2R3|A0A7I2V2R3_HUMAN,tr|A0A7I2V4J6|A0A7I2V4J6_HUMAN,tr|A0A7I2V4G0|A0A7I2V4G0_HUMAN,tr|A0A7I2V402|A0A7I2V402_HUMAN" 6 1720.7824 1.94 71506 20918 3 1720.789312 574.6014 Heterogeneous nuclear ribonucleoprotein A3 OS=Homo sapiens OX=9606 GN=HNRNPA3 PE=1 SV=2 4.13 3425.5 - 87434.3 - - - 4.0075 - 2.631 0.561 - 90.5 1 2 0 0.0069 15 0 0 0 4.55E+06 2.34E+06 - - - 7.3169 1 221125_WJC_METTL3_EV_vs_WT_F05.20923.20923.2 5.17E-10 20/32 R.AETEC[160.03]QNTEYQQLLDIK.L "sp|P13645|K1C10_HUMAN,tr|A0A1B0GVI3|A0A1B0GVI3_HUMAN" 2 2081.9576 999 71509 20923 2 2081.960751 1041.9861 "Keratin, type I cytoskeletal 10 OS=Homo sapiens OX=9606 GN=KRT10 PE=1 SV=6" 4 3426.2 - 583394 - - - 1.5375 - 4.111 0.709 - 1510.1 1 2 0 0.0032 17 0 0 0 2.96E+09 0.00E+00 - - - 7.7522 1 221125_WJC_METTL3_EV_vs_WT_F05.20926.20926.3 3.08E-06 15/84 K.VREATNDDPWGPSGQLMGEIAK.A sp|Q14677|EPN4_HUMAN 1 2370.1274 1.29 71512 20926 3 2370.124742 791.0497 Clathrin interactor 1 OS=Homo sapiens OX=9606 GN=CLINT1 PE=1 SV=1 4.32 3426.6 - 261205 - - - -1.1253 - 3.865 0.614 - 183.4 1 2 1 -0.0027 22 0 0 0 2.35E+06 1.82E+06 - - - 8.59 1 221125_WJC_METTL3_EV_vs_WT_F05.20929.20929.3 2.21E-15 22/76 K.EQANAVSEAVVSSVNTVATK.T sp|O76070|SYUG_HUMAN 1 2003.0171 2.74 71515 20929 3 2003.021368 668.6796 Gamma-synuclein OS=Homo sapiens OX=9606 GN=SNCG PE=1 SV=2 4.53 3427 - 219286 - - - 2.1238 - 3.721 0.681 - 634.3 1 2 0 0.0043 20 0 0 0 5.60E+07 2.04E+07 - - - 9.3191 1 221125_WJC_METTL3_EV_vs_WT_F05.20932.20932.2 9.00E-10 16/36 K.DATNVGDEGGFAPNILENK.E "sp|P06733|ENOA_HUMAN,tr|A0A2R8Y6G6|A0A2R8Y6G6_HUMAN" 2 1959.9174 1.71 71518 20932 2 1959.922489 980.966 Alpha-enolase OS=Homo sapiens OX=9606 GN=ENO1 PE=1 SV=2 3.92 3427.4 - 49214.2 - - - 2.5965 - 3.405 0.697 - 693 1 2 0 0.0051 19 0 0 0 1.73E+08 1.01E+08 - - - 7.1998 0.998 221125_WJC_METTL3_EV_vs_WT_F05.20934.20934.4 1.81E-08 18/108 K.K[136.11]ISSIQSIVPALEIANAHR[166.11].K "sp|P10809|CH60_HUMAN,tr|A0A7I2V2X6|A0A7I2V2X6_HUMAN,tr|A0A7I2YQK6|A0A7I2YQK6_HUMAN,tr|A0A7I2V599|A0A7I2V599_HUMAN,tr|A0A7I2YQ71|A0A7I2YQ71_HUMAN,tr|A0A7I2V5M1|A0A7I2V5M1_HUMAN,tr|A0A7I2V5K3|A0A7I2V5K3_HUMAN,tr|A0A7I2V369|A0A7I2V369_HUMAN" 8 2064.181 1.26 71519 20934 4 2064.187278 517.0525 "60 kDa heat shock protein, mitochondrial OS=Homo sapiens OX=9606 GN=HSPD1 PE=1 SV=2" 8.75 3427.6 - 694102 - - - 3.0206 - 3.536 0.3 - 237.5 1 2 0 0.0062 19 0 0 0 1.63E+08 1.29E+08 - - - 2.2627 0.9999 221125_WJC_METTL3_EV_vs_WT_F05.20937.20937.3 1.65E-07 13/72 K.DATNVGDEGGFAPNILENK.E "sp|P06733|ENOA_HUMAN,tr|A0A2R8Y6G6|A0A2R8Y6G6_HUMAN" 2 1959.9174 1.94 71522 20937 3 1959.921432 654.3131 Alpha-enolase OS=Homo sapiens OX=9606 GN=ENO1 PE=1 SV=2 3.92 3428 - 351727 - - - 2.0572 - 2.456 0.538 - 171.1 1 2 0 0.004 19 0 0 0 1.55E+08 8.02E+07 - - - 6.7446 0.9999 221125_WJC_METTL3_EV_vs_WT_F05.20938.20938.3 3.17E-09 Oct-56 R.GFAFVTFDDHDTVDK.L "sp|P51991|ROA3_HUMAN,tr|A0A7I2V5D8|A0A7I2V5D8_HUMAN,tr|A0A7I2V2R3|A0A7I2V2R3_HUMAN,tr|A0A7I2V4J6|A0A7I2V4J6_HUMAN,tr|A0A7I2V4G0|A0A7I2V4G0_HUMAN,tr|A0A7I2V402|A0A7I2V402_HUMAN" 6 1712.7682 1.94 71523 20938 3 1712.765535 571.93 Heterogeneous nuclear ribonucleoprotein A3 OS=Homo sapiens OX=9606 GN=HNRNPA3 PE=1 SV=2 4.13 3428.2 - 331868 - - - -1.5653 - 2.51 0.475 - 73.2 1 2 0 -0.0027 15 0 0 0 4.55E+06 2.34E+06 - - - 6.2364 0.9997 221125_WJC_METTL3_EV_vs_WT_F05.20939.20939.3 2.20E-08 16/76 K.EQANAVSEAVVSSVNTVATK[136.11].T sp|O76070|SYUG_HUMAN 1 2011.0313 2.74 71524 20939 3 2011.041817 671.351 Gamma-synuclein OS=Homo sapiens OX=9606 GN=SNCG PE=1 SV=2 4.53 3428.3 - 315347 - - - 5.2227 - 3.085 0.549 - 287.1 1 2 0 0.0105 20 0 0 0 5.60E+07 2.04E+07 - - - 7.3909 1 221125_WJC_METTL3_EV_vs_WT_F05.20944.20944.4 6.71E-05 7/114 K.MITEHTSNDPYC[160.03]FVEFYEHR.D "sp|Q01085|TIAR_HUMAN,tr|E7ETC0|E7ETC0_HUMAN,tr|A6NKZ9|A6NKZ9_HUMAN,tr|E7ETJ9|E7ETJ9_HUMAN" 4 2574.0944 1.67 71529 20944 4 2574.099155 644.5309 Nucleolysin TIAR OS=Homo sapiens OX=9606 GN=TIAL1 PE=1 SV=1 4.8 3428.9 - 118195 - - - 1.8492 - 1.776 0.582 - 22.4 1 2 0 0.0048 20 0 0 0 9.01E+05 5.40E+05 - - - 4.4824 0.9999 221125_WJC_METTL3_EV_vs_WT_F05.20945.20945.3 0.000802 Sep-44 K.GISDLAQHYLMR[166.11].A "sp|P49368|TCPG_HUMAN,tr|B4DUR8|B4DUR8_HUMAN" 2 1412.711 0.12 71530 20945 3 1412.712194 471.9109 T-complex protein 1 subunit gamma OS=Homo sapiens OX=9606 GN=CCT3 PE=1 SV=4 6.74 3429.1 - 88643.3 - - - 0.853 - 1.961 0.445 - 85.6 1 2 0 0.0012 12 0 0 0 2.10E+05 1.75E+06 - - - 5.3677 1 221125_WJC_METTL3_EV_vs_WT_F05.20948.20948.3 0.000114 17/72 R.KEELNAISGPNEFAEFYNR.L sp|Q12874|SF3A3_HUMAN 1 2227.0546 4.37 71531 20948 3 2227.059295 743.3588 Splicing factor 3A subunit 3 OS=Homo sapiens OX=9606 GN=SF3A3 PE=1 SV=1 4.49 3429.5 - 1.09E+06 - - - 2.1252 - 3.53 0.52 - 333.5 1 2 0 0.0047 19 0 0 0 1.41E+08 3.23E+07 - - - 7.4349 1 221125_WJC_METTL3_EV_vs_WT_F05.20950.20950.3 1.19E-08 15/72 K.DATNVGDEGGFAPNILENK[136.11].E "sp|P06733|ENOA_HUMAN,tr|A0A2R8Y6G6|A0A2R8Y6G6_HUMAN" 2 1967.9316 1.94 71533 20950 3 1967.933771 656.9845 Alpha-enolase OS=Homo sapiens OX=9606 GN=ENO1 PE=1 SV=2 3.92 3429.7 - 820967 - - - 1.1032 - 2.807 0.636 - 232.6 1 2 0 0.0022 19 0 0 0 1.55E+08 8.02E+07 - - - 8.1659 1 221125_WJC_METTL3_EV_vs_WT_F05.20961.20961.3 1.02E-11 19/72 R.K[136.11]EELNAISGPNEFAEFYNR[166.11].L sp|Q12874|SF3A3_HUMAN 1 2245.077 4.36 71542 20961 3 2245.075224 749.3663 Splicing factor 3A subunit 3 OS=Homo sapiens OX=9606 GN=SF3A3 PE=1 SV=1 4.49 3431.2 - 376011 - - - -0.8053 - 3.602 0.674 - 494 1 2 0 -0.0018 19 0 0 0 1.41E+08 3.23E+07 - - - 9.2023 1 221125_WJC_METTL3_EV_vs_WT_F05.20981.20981.2 1.62E-10 19/36 K.DATNVGDEGGFAPNILENK[136.11].E "sp|P06733|ENOA_HUMAN,tr|A0A2R8Y6G6|A0A2R8Y6G6_HUMAN" 2 1967.9316 1.71 71552 20981 2 1967.926005 984.9731 Alpha-enolase OS=Homo sapiens OX=9606 GN=ENO1 PE=1 SV=2 3.92 3433.8 - 2.48E+06 - - - -2.8431 - 3.795 0.665 - 963.6 1 2 0 -0.0056 19 0 0 0 1.73E+08 1.01E+08 - - - 7.2299 0.9913 221125_WJC_METTL3_EV_vs_WT_F05.20989.20989.3 6.05E-05 13/88 K.SPSDPSHVSVPPPPLLLPAATTR.S "sp|Q8NDX5|PHC3_HUMAN,tr|H7C4H9|H7C4H9_HUMAN,tr|E7EX82|E7EX82_HUMAN" 3 2335.2536 6.12 71556 20989 3 2335.238398 779.4251 Polyhomeotic-like protein 3 OS=Homo sapiens OX=9606 GN=PHC3 PE=1 SV=1 6.46 3434.6 - 281676 - - - -6.5081 - 2.453 0.356 - 130.4 1 2 0 -0.0152 23 0 0 0 4.03E+07 6.59E+06 - - - 4.6099 0.9999 221125_WJC_METTL3_EV_vs_WT_F05.20991.20991.3 4.22E-05 18/72 K.K[136.11]ISSIQSIVPALEIANAHR[166.11].K "sp|P10809|CH60_HUMAN,tr|A0A7I2V2X6|A0A7I2V2X6_HUMAN,tr|A0A7I2YQK6|A0A7I2YQK6_HUMAN,tr|A0A7I2V599|A0A7I2V599_HUMAN,tr|A0A7I2YQ71|A0A7I2YQ71_HUMAN,tr|A0A7I2V5M1|A0A7I2V5M1_HUMAN,tr|A0A7I2V5K3|A0A7I2V5K3_HUMAN,tr|A0A7I2V369|A0A7I2V369_HUMAN" 8 2064.181 1.51 71557 20991 3 2064.17354 689.0676 "60 kDa heat shock protein, mitochondrial OS=Homo sapiens OX=9606 GN=HSPD1 PE=1 SV=2" 8.75 3434.8 - 575971 - - - -3.6349 - 3.304 0.564 - 353.9 1 2 0 -0.0075 19 0 0 0 4.87E+07 3.22E+07 - - - 7.7622 1 221125_WJC_METTL3_EV_vs_WT_F05.20993.20993.3 5.36E-11 23/72 K.KISSIQSIVPALEIANAHR.K "sp|P10809|CH60_HUMAN,tr|A0A7I2V2X6|A0A7I2V2X6_HUMAN,tr|A0A7I2YQK6|A0A7I2YQK6_HUMAN,tr|A0A7I2V599|A0A7I2V599_HUMAN,tr|A0A7I2YQ71|A0A7I2YQ71_HUMAN,tr|A0A7I2V5M1|A0A7I2V5M1_HUMAN,tr|A0A7I2V5K3|A0A7I2V5K3_HUMAN,tr|A0A7I2V369|A0A7I2V369_HUMAN" 8 2046.1586 1.52 71558 20993 3 2046.156996 683.0601 "60 kDa heat shock protein, mitochondrial OS=Homo sapiens OX=9606 GN=HSPD1 PE=1 SV=2" 8.75 3435 - 767589 - - - -0.7707 - 4.281 0.612 - 578.2 1 2 0 -0.0016 19 0 0 0 4.84E+07 3.19E+07 - - - 8.9354 0.9502 221125_WJC_METTL3_EV_vs_WT_F05.21015.21015.2 0.000346 18-Oct V.PALEIANAHR.K "sp|P10809|CH60_HUMAN,tr|A0A7I2V2X6|A0A7I2V2X6_HUMAN,tr|A0A7I2YQK6|A0A7I2YQK6_HUMAN,tr|A0A7I2V599|A0A7I2V599_HUMAN,tr|A0A7I2YQ71|A0A7I2YQ71_HUMAN,tr|A0A7I2V5M1|A0A7I2V5M1_HUMAN,tr|A0A7I2V5K3|A0A7I2V5K3_HUMAN,tr|A0A7I2V369|A0A7I2V369_HUMAN" 8 1090.5883 1.68 71567 21015 2 1090.584495 546.3014 "60 kDa heat shock protein, mitochondrial OS=Homo sapiens OX=9606 GN=HSPD1 PE=1 SV=2" 7.18 3438 - 224307 - - - -3.5275 - 2.449 0.428 - 393.6 1 1 0 -0.0038 10 0 0 0 7.12E+06 4.24E+06 - - - 4.7011 1 221125_WJC_METTL3_EV_vs_WT_F05.21017.21017.4 7.70E-05 22/138 K.LNC[160.03]QVIGASVDSHFC[160.03]HLAWVNTPK[136.11].K "sp|Q06830|PRDX1_HUMAN,tr|A0A0A0MSI0|A0A0A0MSI0_HUMAN" 2 2760.3356 0.17 71568 21017 4 2760.332071 691.0912 Peroxiredoxin-1 OS=Homo sapiens OX=9606 GN=PRDX1 PE=1 SV=1 6.9 3438.2 - 901748 - - - -1.2694 - 4.354 0.614 - 382 1 2 0 -0.0035 24 0 0 0 4.60E+06 2.73E+07 - - - 5.0415 0.9998 221125_WJC_METTL3_EV_vs_WT_F05.21027.21027.3 3.93E-06 14/88 R.GSTAPVGGGAFPTIVEREPWDGR.D sp|Q15084|PDIA6_HUMAN 1 2355.1608 2.81 71575 21027 3 2355.162285 786.0609 Protein disulfide-isomerase A6 OS=Homo sapiens OX=9606 GN=PDIA6 PE=1 SV=1 4.68 3439.5 - 920636 - - - 0.6484 - 2.274 0.493 - 141.1 1 2 1 0.0015 23 0 0 0 2.59E+07 9.21E+06 - - - 5.9633 0.9805 221125_WJC_METTL3_EV_vs_WT_F05.21033.21033.3 0.00781 13/104 Q.QSTNPAPGILGPPPPSFHLGGPAVGPR.G "sp|P43243|MATR3_HUMAN,tr|D6RE02|D6RE02_HUMAN,tr|B3KM87|B3KM87_HUMAN,tr|A8MXP9|A8MXP9_HUMAN,tr|D6RAY2|D6RAY2_HUMAN,tr|D6R991|D6R991_HUMAN,tr|A0A0R4J2E8|A0A0R4J2E8_HUMAN,tr|D6RAM9|D6RAM9_HUMAN,tr|D6RIA2|D6RIA2_HUMAN,tr|H0Y8T4|H0Y8T4_HUMAN,tr|D6REM6|D6REM6_HUMAN,tr|D6RBI2|D6RBI2_HUMAN" 12 2617.3765 1.7 71579 21033 3 2617.381458 873.4661 Matrin-3 OS=Homo sapiens OX=9606 GN=MATR3 PE=1 SV=2 9.76 3440.4 - 145117 - - - 1.8924 - 2.428 0.41 - 87 1 1 0 0.005 27 0 0 0 5.48E+06 3.22E+06 - - - 5.1505 1 221125_WJC_METTL3_EV_vs_WT_F05.21035.21035.3 2.55E-10 18/64 R.AETEC[160.03]QNTEYQQLLDIK.L "sp|P13645|K1C10_HUMAN,tr|A0A1B0GVI3|A0A1B0GVI3_HUMAN" 2 2081.9576 6921.48 71580 21035 3 2081.95958 694.9931 "Keratin, type I cytoskeletal 10 OS=Homo sapiens OX=9606 GN=KRT10 PE=1 SV=6" 4 3440.7 - 1.44E+07 - - - 0.975 - 3.129 0.617 - 502.7 1 2 0 0.002 17 0 0 0 6.62E+09 9.56E+05 - - - 8.3002 1 221125_WJC_METTL3_EV_vs_WT_F05.21036.21036.3 6.44E-13 26/80 R.AEGEWEDQEALDYFSDKESGK.Q "sp|Q9NYF8|BCLF1_HUMAN,tr|E9PKI6|E9PKI6_HUMAN,tr|A0A1W2PQ43|A0A1W2PQ43_HUMAN,tr|E9PK91|E9PK91_HUMAN,tr|E9PK09|E9PK09_HUMAN,tr|E9PQN2|E9PQN2_HUMAN" 6 2432.0292 2.78 71581 21036 3 2432.030626 811.6837 Bcl-2-associated transcription factor 1 OS=Homo sapiens OX=9606 GN=BCLAF1 PE=1 SV=2 3.89 3440.8 - 700396 - - - 0.5884 - 4.46 0.736 - 886.9 1 2 1 0.0014 21 0 0 0 3.81E+07 1.37E+07 - - - 10.3298 0.9999 221125_WJC_METTL3_EV_vs_WT_F05.21038.21038.3 2.74E-10 13/80 R.C[160.03]DVTDNQSEVADKTEDYLWLK.L "sp|Q8N1F7|NUP93_HUMAN,tr|H3BPA9|H3BPA9_HUMAN,tr|H3BVG0|H3BVG0_HUMAN" 3 2528.1377 2.38 71583 21038 3 2528.137019 843.7198 Nuclear pore complex protein Nup93 OS=Homo sapiens OX=9606 GN=NUP93 PE=1 SV=2 3.96 3441.1 - 443823 - - - -0.2694 - 2.597 0.582 - 110.1 1 2 1 -0.0007 21 0 0 0 1.03E+07 4.34E+06 - - - 7.3166 0.9997 221125_WJC_METTL3_EV_vs_WT_F05.21039.21039.3 1.15E-05 Dec-80 R.C[160.03]DVTDNQSEVADK[136.11]TEDYLWLK[136.11].L "sp|Q8N1F7|NUP93_HUMAN,tr|H3BPA9|H3BPA9_HUMAN,tr|H3BVG0|H3BVG0_HUMAN" 3 2544.1661 2.38 71584 21039 3 2544.158136 849.0626 Nuclear pore complex protein Nup93 OS=Homo sapiens OX=9606 GN=NUP93 PE=1 SV=2 3.96 3441.2 - 260991 - - - -3.1303 - 2.464 0.612 - 95.7 1 2 1 -0.008 21 0 0 0 1.03E+07 4.34E+06 - - - 7.523 1 221125_WJC_METTL3_EV_vs_WT_F05.21047.21047.3 4.29E-08 24/84 K.GPAVGIDLGTTYSC[160.03]VGVFQHGK[136.11].V "sp|P11142|HSP7C_HUMAN,tr|E9PQQ4|E9PQQ4_HUMAN,tr|E9PNE6|E9PNE6_HUMAN,tr|E9PKE3|E9PKE3_HUMAN,tr|E9PLF4|E9PLF4_HUMAN,tr|E9PI65|E9PI65_HUMAN,tr|E9PK54|E9PK54_HUMAN,tr|E9PN25|E9PN25_HUMAN,tr|E9PPY6|E9PPY6_HUMAN,tr|E9PQK7|E9PQK7_HUMAN" 10 2270.1245 0.12 71590 21047 3 2270.126189 757.7154 Heat shock cognate 71 kDa protein OS=Homo sapiens OX=9606 GN=HSPA8 PE=1 SV=1 6.73 3442.2 - 688247 - - - 0.7427 - 3.625 0.656 - 492.9 1 2 0 0.0017 22 0 0 0 7.08E+06 5.77E+07 - - - 8.9066 1 221125_WJC_METTL3_EV_vs_WT_F05.21049.21049.3 1.36E-12 25/84 R.LAELEEFINGPNNAHIQQVGDR.C "sp|Q00610|CLH1_HUMAN,tr|J3KS13|J3KS13_HUMAN,tr|A0A087WVQ6|A0A087WVQ6_HUMAN" 3 2463.2142 1.06 71592 21049 3 2463.216944 822.0787 Clathrin heavy chain 1 OS=Homo sapiens OX=9606 GN=CLTC PE=1 SV=5 4.4 3442.4 - 563264 - - - 1.0937 - 4.797 0.552 - 942.3 1 2 0 0.0027 22 0 0 0 3.40E+07 3.20E+07 - - - 8.411 0.9999 221125_WJC_METTL3_EV_vs_WT_F05.21051.21051.3 0.0185 14/56 R.GFGFVTFDDHDPVDK[136.11].L "sp|P22626|ROA2_HUMAN,tr|A0A7I2V4N0|A0A7I2V4N0_HUMAN,tr|A0A024RA28|A0A024RA28_HUMAN,tr|A0A7I2V4N1|A0A7I2V4N1_HUMAN,tr|A0A7I2V4I6|A0A7I2V4I6_HUMAN,tr|A0A087WUI2|A0A087WUI2_HUMAN,tr|A0A7I2V4S4|A0A7I2V4S4_HUMAN,tr|A0A7I2V323|A0A7I2V323_HUMAN,tr|A0A7I2V3P1|A0A7I2V3P1_HUMAN,tr|A0A7I2V3P7|A0A7I2V3P7_HUMAN" 10 1702.7719 1.25 71594 21051 3 1702.774514 568.5979 Heterogeneous nuclear ribonucleoproteins A2\B1 OS=Homo sapiens OX=9606 GN=HNRNPA2B1 PE=1 SV=2 4.13 3442.7 - 345172 - - - 1.5639 - 2.123 0.499 - 174.7 1 2 0 0.0027 15 0 0 0 1.23E+07 9.83E+06 - - - 6.067 0.9981 221125_WJC_METTL3_EV_vs_WT_F05.21052.21052.3 5.01E-07 16/100 Q.STNPAPGILGPPPPSFHLGGPAVGPR.G "sp|P43243|MATR3_HUMAN,tr|D6RE02|D6RE02_HUMAN,tr|B3KM87|B3KM87_HUMAN,tr|A8MXP9|A8MXP9_HUMAN,tr|D6RAY2|D6RAY2_HUMAN,tr|D6R991|D6R991_HUMAN,tr|A0A0R4J2E8|A0A0R4J2E8_HUMAN,tr|D6RAM9|D6RAM9_HUMAN,tr|D6RIA2|D6RIA2_HUMAN,tr|H0Y8T4|H0Y8T4_HUMAN,tr|D6REM6|D6REM6_HUMAN,tr|D6RBI2|D6RBI2_HUMAN" 12 2489.3179 2.15 71595 21052 3 2489.321172 830.7799 Matrin-3 OS=Homo sapiens OX=9606 GN=MATR3 PE=1 SV=2 9.49 3442.8 - 242985 - - - 1.3032 - 3.36 0.562 - 187.5 1 1 0 0.0032 26 0 0 0 6.51E+07 3.02E+07 - - - 7.5931 0.9999 221125_WJC_METTL3_EV_vs_WT_F05.21054.21054.4 0.000422 13/126 K.ESVELPLTHPEYYEEMGIK[136.11]PPK[136.11].G "sp|P62191|PRS4_HUMAN,tr|G3V4X1|G3V4X1_HUMAN" 2 2601.3007 1.46 71597 21054 4 2601.299698 651.3325 26S proteasome regulatory subunit 4 OS=Homo sapiens OX=9606 GN=PSMC1 PE=1 SV=1 4.64 3443.1 - 193353 - - - -0.4013 - 2.262 0.45 - 73.8 1 2 0 -0.001 22 0 0 0 7.18E+06 4.92E+06 - - - 3.4096 1 221125_WJC_METTL3_EV_vs_WT_F05.21059.21059.3 5.17E-09 17/56 R.GFGFVTFDDHDPVDK.L "sp|P22626|ROA2_HUMAN,tr|A0A7I2V4N0|A0A7I2V4N0_HUMAN,tr|A0A024RA28|A0A024RA28_HUMAN,tr|A0A7I2V4N1|A0A7I2V4N1_HUMAN,tr|A0A7I2V4I6|A0A7I2V4I6_HUMAN,tr|A0A087WUI2|A0A087WUI2_HUMAN,tr|A0A7I2V4S4|A0A7I2V4S4_HUMAN,tr|A0A7I2V323|A0A7I2V323_HUMAN,tr|A0A7I2V3P1|A0A7I2V3P1_HUMAN,tr|A0A7I2V3P7|A0A7I2V3P7_HUMAN" 10 1694.7577 1.25 71600 21059 3 1694.758603 565.9265 Heterogeneous nuclear ribonucleoproteins A2\B1 OS=Homo sapiens OX=9606 GN=HNRNPA2B1 PE=1 SV=2 4.13 3443.6 - 802469 - - - 0.5617 - 2.612 0.641 - 202.7 1 2 0 0.001 15 0 0 0 1.23E+07 9.83E+06 - - - 8.1915 1 221125_WJC_METTL3_EV_vs_WT_F05.21061.21061.3 1.02E-16 29/80 R.AEGEWEDQEALDYFSDK[136.11]ESGK[136.11].Q "sp|Q9NYF8|BCLF1_HUMAN,tr|E9PKI6|E9PKI6_HUMAN,tr|A0A1W2PQ43|A0A1W2PQ43_HUMAN,tr|E9PK91|E9PK91_HUMAN,tr|E9PK09|E9PK09_HUMAN,tr|E9PQN2|E9PQN2_HUMAN" 6 2448.0576 2.78 71602 21061 3 2448.051793 817.0265 Bcl-2-associated transcription factor 1 OS=Homo sapiens OX=9606 GN=BCLAF1 PE=1 SV=2 3.89 3443.9 - 1.28E+06 - - - -2.37 - 4.931 0.791 - 1179 1 2 1 -0.0058 21 0 0 0 3.81E+07 1.37E+07 - - - 11.1825 0.7975 221125_WJC_METTL3_EV_vs_WT_F05.21063.21063.3 0.00615 13/76 R.IK[136.11]DFLQGSSC[160.03]IAGIYNETTK[136.11].Q sp|P15924|DESP_HUMAN 1 2260.138 11.43 71604 21063 3 2261.129323 754.3866 Desmoplakin OS=Homo sapiens OX=9606 GN=DSP PE=1 SV=3 6.06 3444.2 - 418891 - - - 438.5967 - 1.969 0.48 - 144.2 1 2 1 0.9913 20 0 0 0 4.44E+07 3.88E+06 - - - 5.2606 0.9984 221125_WJC_METTL3_EV_vs_WT_F05.21064.21064.3 1.19E-09 21/100 Q.STNPAPGILGPPPPSFHLGGPAVGPR[166.11].G "sp|P43243|MATR3_HUMAN,tr|D6RE02|D6RE02_HUMAN,tr|B3KM87|B3KM87_HUMAN,tr|A8MXP9|A8MXP9_HUMAN,tr|D6RAY2|D6RAY2_HUMAN,tr|D6R991|D6R991_HUMAN,tr|A0A0R4J2E8|A0A0R4J2E8_HUMAN,tr|D6RAM9|D6RAM9_HUMAN,tr|D6RIA2|D6RIA2_HUMAN,tr|H0Y8T4|H0Y8T4_HUMAN,tr|D6REM6|D6REM6_HUMAN,tr|D6RBI2|D6RBI2_HUMAN" 12 2499.3262 2.15 71605 21064 3 2499.325374 834.116 Matrin-3 OS=Homo sapiens OX=9606 GN=MATR3 PE=1 SV=2 9.49 3444.3 - 375588 - - - -0.3297 - 4.208 0.508 - 428.5 1 1 0 -0.0008 26 0 0 0 6.88E+07 3.20E+07 - - - 7.5095 0.9955 221125_WJC_METTL3_EV_vs_WT_F05.21065.21065.3 1.31E-06 19/104 Q.QSTNPAPGILGPPPPSFHLGGPAVGPR[166.11].G "sp|P43243|MATR3_HUMAN,tr|D6RE02|D6RE02_HUMAN,tr|B3KM87|B3KM87_HUMAN,tr|A8MXP9|A8MXP9_HUMAN,tr|D6RAY2|D6RAY2_HUMAN,tr|D6R991|D6R991_HUMAN,tr|A0A0R4J2E8|A0A0R4J2E8_HUMAN,tr|D6RAM9|D6RAM9_HUMAN,tr|D6RIA2|D6RIA2_HUMAN,tr|H0Y8T4|H0Y8T4_HUMAN,tr|D6REM6|D6REM6_HUMAN,tr|D6RBI2|D6RBI2_HUMAN" 12 2627.3848 1.91 71606 21065 3 2627.391978 876.8022 Matrin-3 OS=Homo sapiens OX=9606 GN=MATR3 PE=1 SV=2 9.76 3444.4 - 283507 - - - 2.7415 - 3.488 0.563 - 312.8 1 1 0 0.0072 27 0 0 0 1.05E+07 5.50E+06 - - - 7.6892 1 221125_WJC_METTL3_EV_vs_WT_F05.21077.21077.3 1.01E-08 17/88 K.SPSDPSHVSVPPPPLLLPAATTR[166.11].S "sp|Q8NDX5|PHC3_HUMAN,tr|H7C4H9|H7C4H9_HUMAN,tr|E7EX82|E7EX82_HUMAN" 3 2345.2619 5.99 71616 21077 3 2345.265343 782.7612 Polyhomeotic-like protein 3 OS=Homo sapiens OX=9606 GN=PHC3 PE=1 SV=1 6.46 3446 - 255974 - - - 1.4826 - 3.391 0.615 - 290.3 1 2 0 0.0035 23 0 0 0 3.93E+07 6.56E+06 - - - 8.2604 1 221125_WJC_METTL3_EV_vs_WT_F05.21082.21082.3 0.000841 19/76 R.IKDFLQGSSC[160.03]IAGIYNETTK.Q sp|P15924|DESP_HUMAN 1 2244.1096 8.88 71619 21082 3 2244.1091 749.0438 Desmoplakin OS=Homo sapiens OX=9606 GN=DSP PE=1 SV=3 6.06 3446.7 - 2.25E+06 - - - -0.238 - 3.45 0.59 - 324.6 1 2 1 -0.0005 20 0 0 0 4.46E+07 5.02E+06 - - - 8.1221 1 221125_WJC_METTL3_EV_vs_WT_F05.21085.21085.3 4.49E-07 21/96 S.TNPAPGILGPPPPSFHLGGPAVGPR.G "sp|P43243|MATR3_HUMAN,tr|D6RE02|D6RE02_HUMAN,tr|B3KM87|B3KM87_HUMAN,tr|A8MXP9|A8MXP9_HUMAN,tr|D6RAY2|D6RAY2_HUMAN,tr|D6R991|D6R991_HUMAN,tr|A0A0R4J2E8|A0A0R4J2E8_HUMAN,tr|D6RAM9|D6RAM9_HUMAN,tr|D6RIA2|D6RIA2_HUMAN,tr|H0Y8T4|H0Y8T4_HUMAN,tr|D6REM6|D6REM6_HUMAN,tr|D6RBI2|D6RBI2_HUMAN" 12 2402.2859 1.76 71622 21085 3 2402.287368 801.7692 Matrin-3 OS=Homo sapiens OX=9606 GN=MATR3 PE=1 SV=2 9.44 3447 - 522144 - - - 0.6115 - 4.277 0.639 - 456.3 1 1 0 0.0015 25 0 0 0 1.85E+07 1.05E+07 - - - 9.0072 0.9854 221125_WJC_METTL3_EV_vs_WT_F05.21087.21087.2 0.00385 18-Nov V.PALEIANAHR[166.11].K "sp|P10809|CH60_HUMAN,tr|A0A7I2V2X6|A0A7I2V2X6_HUMAN,tr|A0A7I2YQK6|A0A7I2YQK6_HUMAN,tr|A0A7I2V599|A0A7I2V599_HUMAN,tr|A0A7I2YQ71|A0A7I2YQ71_HUMAN,tr|A0A7I2V5M1|A0A7I2V5M1_HUMAN,tr|A0A7I2V5K3|A0A7I2V5K3_HUMAN,tr|A0A7I2V369|A0A7I2V369_HUMAN" 8 1100.5966 1.35 71624 21087 2 1100.597103 551.3056 "60 kDa heat shock protein, mitochondrial OS=Homo sapiens OX=9606 GN=HSPD1 PE=1 SV=2" 7.18 3447.3 - 454507 - - - 0.4461 - 2.562 0.303 - 573.9 1 1 0 0.0005 10 0 0 0 1.02E+08 7.56E+07 - - - 3.9048 0.9933 221125_WJC_METTL3_EV_vs_WT_F05.21092.21092.2 4.26E-05 13/20 L.VPALEIANAHR.K "sp|P10809|CH60_HUMAN,tr|A0A7I2V2X6|A0A7I2V2X6_HUMAN,tr|A0A7I2YQK6|A0A7I2YQK6_HUMAN,tr|A0A7I2V599|A0A7I2V599_HUMAN,tr|A0A7I2YQ71|A0A7I2YQ71_HUMAN,tr|A0A7I2V5M1|A0A7I2V5M1_HUMAN,tr|A0A7I2V5K3|A0A7I2V5K3_HUMAN,tr|A0A7I2V369|A0A7I2V369_HUMAN" 8 1189.6568 0.93 71629 21092 2 1189.656841 595.8357 "60 kDa heat shock protein, mitochondrial OS=Homo sapiens OX=9606 GN=HSPD1 PE=1 SV=2" 6.72 3448 - 177565 - - - 0.0723 - 2.378 0.49 - 828.8 1 1 0 0.0001 11 0 0 0 3.25E+07 3.49E+07 - - - 5.0036 1 221125_WJC_METTL3_EV_vs_WT_F05.21094.21094.3 7.11E-07 14/60 R.QTQPVLQSQVENLLHR.T sp|O60318|GANP_HUMAN 1 1889.0119 4.16 71630 21094 3 1889.015393 630.6779 Germinal-center associated nuclear protein OS=Homo sapiens OX=9606 GN=MCM3AP PE=1 SV=2 6.75 3448.2 - 271530 - - - 1.8444 - 2.861 0.525 - 311.8 1 2 0 0.0035 16 0 0 0 1.14E+07 2.73E+06 - - - 7.0894 1 221125_WJC_METTL3_EV_vs_WT_F05.21096.21096.3 4.53E-09 28/84 R.LAELEEFINGPNNAHIQQVGDR[166.11].C "sp|Q00610|CLH1_HUMAN,tr|J3KS13|J3KS13_HUMAN,tr|A0A087WVQ6|A0A087WVQ6_HUMAN" 3 2473.2225 1.06 71631 21096 3 2473.220318 825.4148 Clathrin heavy chain 1 OS=Homo sapiens OX=9606 GN=CLTC PE=1 SV=5 4.4 3448.4 - 2.30E+06 - - - -0.8903 - 5.036 0.597 - 970.3 1 2 0 -0.0022 22 0 0 0 3.40E+07 3.20E+07 - - - 9.0281 0.888 221125_WJC_METTL3_EV_vs_WT_F05.21105.21105.4 0.000445 14/150 Q.STNPAPGILGPPPPSFHLGGPAVGPR.G "sp|P43243|MATR3_HUMAN,tr|D6RE02|D6RE02_HUMAN,tr|B3KM87|B3KM87_HUMAN,tr|A8MXP9|A8MXP9_HUMAN,tr|D6RAY2|D6RAY2_HUMAN,tr|D6R991|D6R991_HUMAN,tr|A0A0R4J2E8|A0A0R4J2E8_HUMAN,tr|D6RAM9|D6RAM9_HUMAN,tr|D6RIA2|D6RIA2_HUMAN,tr|H0Y8T4|H0Y8T4_HUMAN,tr|D6REM6|D6REM6_HUMAN,tr|D6RBI2|D6RBI2_HUMAN" 12 2489.3179 2.18 71638 21105 4 2489.308594 623.3368 Matrin-3 OS=Homo sapiens OX=9606 GN=MATR3 PE=1 SV=2 9.49 3449.5 - 256313 - - - -3.7496 - 2.165 0.384 - 97.5 1 1 0 -0.0093 26 0 0 0 5.85E+06 2.68E+06 - - - 2.8094 1 221125_WJC_METTL3_EV_vs_WT_F05.21107.21107.3 2.55E-08 19/72 R.AETEC[160.03]QNTEYQQLLDIKIR.L "sp|P13645|K1C10_HUMAN,tr|A0A1B0GVI3|A0A1B0GVI3_HUMAN" 2 2351.1427 15.25 71640 21107 3 2351.14267 784.7215 "Keratin, type I cytoskeletal 10 OS=Homo sapiens OX=9606 GN=KRT10 PE=1 SV=6" 4.41 3449.8 - 305881 - - - -0.0234 - 3.717 0.665 - 602.1 1 2 1 -0.0001 19 0 0 0 5.56E+06 3.65E+05 - - - 9.1797 0.9999 221125_WJC_METTL3_EV_vs_WT_F05.21108.21108.4 2.00E-07 15/156 R.VIISAPSADAPMFVMGVNHEKYDNSLK.L "sp|P04406|G3P_HUMAN,tr|E7EUT5|E7EUT5_HUMAN" 2 2932.4463 0.73 71641 21108 4 2932.450941 734.1189 Glyceraldehyde-3-phosphate dehydrogenase OS=Homo sapiens OX=9606 GN=GAPDH PE=1 SV=3 5.38 3449.9 - 239429 - - - 1.5823 - 2.683 0.538 - 112.8 1 2 1 0.0046 27 0 0 0 2.63E+06 3.63E+06 - - - 4.2163 0.9888 221125_WJC_METTL3_EV_vs_WT_F05.21110.21110.4 0.313 6/126 R.LAELEEFINGPNNAHIQQVGDR[166.11].C "sp|Q00610|CLH1_HUMAN,tr|J3KS13|J3KS13_HUMAN,tr|A0A087WVQ6|A0A087WVQ6_HUMAN" 3 2473.2225 0.82 71643 21110 4 2473.221773 619.3129 Clathrin heavy chain 1 OS=Homo sapiens OX=9606 GN=CLTC PE=1 SV=5 4.4 3450.1 - 148119 - - - -0.302 - 1.261 0.21 - 21 1 2 0 -0.0007 22 0 0 0 1.19E+06 1.45E+06 - - - 1.1295 0.996 221125_WJC_METTL3_EV_vs_WT_F05.21111.21111.4 0.0116 Sep-96 K.STTGPFDREHLLSYLEK.E sp|Q9NYL9|TMOD3_HUMAN 1 1991.9953 1 71644 21111 4 1991.995249 499.0061 Tropomodulin-3 OS=Homo sapiens OX=9606 GN=TMOD3 PE=1 SV=1 5.42 3450.3 - 144176 - - - -0.0035 - 1.825 0.301 - 62.3 1 2 1 0 17 0 0 0 5.20E+06 5.20E+06 - - - 2.0548 0.9999 221125_WJC_METTL3_EV_vs_WT_F05.21123.21123.2 0.000135 18-Sep R.EC[160.03]LNLWGYER[166.11].V sp|Q86U44|MTA70_HUMAN 1 1348.6109 0.03 71652 21123 2 1348.610085 675.3127 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 4.53 3451.8 - 1.90E+06 - - - -0.6347 - 2.064 0.546 - 363.6 1 2 0 -0.0009 10 0 0 0 2.48E+06 7.68E+07 - - - 5.0962 0.9999 221125_WJC_METTL3_EV_vs_WT_F05.21124.21124.2 3.33E-06 28-Nov R.VVSEDFLQDVSASTK[136.11].S "sp|P09874|PARP1_HUMAN,tr|A0A7I2V3E1|A0A7I2V3E1_HUMAN" 2 1631.8134 1.21 71653 21124 2 1631.812331 816.914 Poly [ADP-ribose] polymerase 1 OS=Homo sapiens OX=9606 GN=PARP1 PE=1 SV=4 4.03 3451.9 - 177694 - - - -0.6441 - 2.276 0.576 - 320 1 2 0 -0.0011 15 0 0 0 3.23E+06 2.67E+06 - - - 5.317 1 221125_WJC_METTL3_EV_vs_WT_F05.21128.21128.3 9.72E-06 18/56 R.R[166.11]EEQIVQLLNSVQAK[136.11].N "sp|Q9H2U1|DHX36_HUMAN,tr|E7EWK3|E7EWK3_HUMAN" 2 1771.9911 1.18 71655 21128 3 1771.987981 591.671 ATP-dependent DNA\RNA helicase DHX36 OS=Homo sapiens OX=9606 GN=DHX36 PE=1 SV=2 6.14 3452.4 - 365029 - - - -1.7698 - 3.425 0.543 - 581.5 1 2 0 -0.0031 15 0 0 0 3.04E+07 2.57E+07 - - - 7.8054 1 221125_WJC_METTL3_EV_vs_WT_F05.21135.21135.3 2.83E-09 13/92 K.GILGYTEHQVVSSDFNSDTHSSTF.D "sp|P04406|G3P_HUMAN,tr|E7EUT5|E7EUT5_HUMAN" 2 2627.1776 - 71660 21135 3 2627.172173 876.7331 Glyceraldehyde-3-phosphate dehydrogenase OS=Homo sapiens OX=9606 GN=GAPDH PE=1 SV=3 4.52 3453.4 - 577633 - - - -2.0619 - 3.302 0.678 - 156.5 1 1 0 -0.0054 24 0 0 0 - - - - - 8.8719 0.9676 221125_WJC_METTL3_EV_vs_WT_F05.21136.21136.2 6.46E-06 14/20 L.VPALEIANAHR[166.11].K "sp|P10809|CH60_HUMAN,tr|A0A7I2V2X6|A0A7I2V2X6_HUMAN,tr|A0A7I2YQK6|A0A7I2YQK6_HUMAN,tr|A0A7I2V599|A0A7I2V599_HUMAN,tr|A0A7I2YQ71|A0A7I2YQ71_HUMAN,tr|A0A7I2V5M1|A0A7I2V5M1_HUMAN,tr|A0A7I2V5K3|A0A7I2V5K3_HUMAN,tr|A0A7I2V369|A0A7I2V369_HUMAN" 8 1199.665 0.93 71661 21136 2 1199.662418 600.8398 "60 kDa heat shock protein, mitochondrial OS=Homo sapiens OX=9606 GN=HSPD1 PE=1 SV=2" 6.72 3453.5 - 409068 - - - -2.1731 - 2.561 0.315 - 1096.1 1 1 0 -0.0026 11 0 0 0 3.15E+07 3.39E+07 - - - 3.9108 0.9998 221125_WJC_METTL3_EV_vs_WT_F05.21137.21137.3 2.52E-07 Oct-64 R.ENSASQISQLEQQLSAK.N "sp|Q13948|CASP_HUMAN,sp|P39880|CUX1_HUMAN,tr|A0A2R8Y852|A0A2R8Y852_HUMAN,tr|A0A2R8YDI1|A0A2R8YDI1_HUMAN" 4 1859.9225 1.4 71662 21137 3 1859.924645 620.9814 Protein CASP OS=Homo sapiens OX=9606 GN=CUX1 PE=1 SV=2 4.53 3453.6 - 201636 - - - 1.1613 - 2.254 0.386 - 140.3 1 2 0 0.0022 17 0 0 0 1.99E+07 1.42E+07 - - - 4.8961 1 221125_WJC_METTL3_EV_vs_WT_F05.21138.21138.2 2.64E-08 Dec-32 R.ENSASQISQLEQQLSAK.N "sp|Q13948|CASP_HUMAN,sp|P39880|CUX1_HUMAN,tr|A0A2R8Y852|A0A2R8Y852_HUMAN,tr|A0A2R8YDI1|A0A2R8YDI1_HUMAN" 4 1859.9225 1.4 71663 21138 2 1859.931757 930.9685 Protein CASP OS=Homo sapiens OX=9606 GN=CUX1 PE=1 SV=2 4.53 3453.8 - 165611 - - - 4.9852 - 2.754 0.636 - 331.1 1 2 0 0.0093 17 0 0 0 1.50E+07 1.07E+07 - - - 6.2262 1 221125_WJC_METTL3_EV_vs_WT_F05.21147.21147.4 1.27E-08 22/108 K.KISSIQSIVPALEIANAHR.K "sp|P10809|CH60_HUMAN,tr|A0A7I2V2X6|A0A7I2V2X6_HUMAN,tr|A0A7I2YQK6|A0A7I2YQK6_HUMAN,tr|A0A7I2V599|A0A7I2V599_HUMAN,tr|A0A7I2YQ71|A0A7I2YQ71_HUMAN,tr|A0A7I2V5M1|A0A7I2V5M1_HUMAN,tr|A0A7I2V5K3|A0A7I2V5K3_HUMAN,tr|A0A7I2V369|A0A7I2V369_HUMAN" 8 2046.1586 1.36 71668 21147 4 2046.158899 512.5469 "60 kDa heat shock protein, mitochondrial OS=Homo sapiens OX=9606 GN=HSPD1 PE=1 SV=2" 8.75 3454.9 - 4.13E+07 - - - 0.1593 - 3.528 0.589 - 431.4 1 2 0 0.0003 19 0 0 0 1.44E+09 1.06E+09 - - - 4.779 0.9916 221125_WJC_METTL3_EV_vs_WT_F05.21148.21148.2 7.22E-06 24-Nov Q.SIVPALEIANAHR.K "sp|P10809|CH60_HUMAN,tr|A0A7I2V2X6|A0A7I2V2X6_HUMAN,tr|A0A7I2YQK6|A0A7I2YQK6_HUMAN,tr|A0A7I2V599|A0A7I2V599_HUMAN,tr|A0A7I2YQ71|A0A7I2YQ71_HUMAN,tr|A0A7I2V5M1|A0A7I2V5M1_HUMAN,tr|A0A7I2V5K3|A0A7I2V5K3_HUMAN,tr|A0A7I2V369|A0A7I2V369_HUMAN" 8 1389.7728 1.45 71669 21148 2 1389.772303 695.8937 "60 kDa heat shock protein, mitochondrial OS=Homo sapiens OX=9606 GN=HSPD1 PE=1 SV=2" 6.47 3455 - 605540 - - - -0.3922 - 2.182 0.482 - 318.3 1 1 0 -0.0005 13 0 0 0 2.85E+07 1.97E+07 - - - 4.6034 1 221125_WJC_METTL3_EV_vs_WT_F05.21149.21149.2 1.73E-07 13/32 R.ENSASQISQLEQQLSAK[136.11].N "sp|Q13948|CASP_HUMAN,sp|P39880|CUX1_HUMAN,tr|A0A2R8Y852|A0A2R8Y852_HUMAN,tr|A0A2R8YDI1|A0A2R8YDI1_HUMAN" 4 1867.9367 1.4 71670 21149 2 1867.93406 934.9756 Protein CASP OS=Homo sapiens OX=9606 GN=CUX1 PE=1 SV=2 4.53 3455.1 - 347179 - - - -1.4053 - 2.764 0.598 - 368.2 1 2 0 -0.0026 17 0 0 0 1.50E+07 1.07E+07 - - - 5.9566 0.9999 221125_WJC_METTL3_EV_vs_WT_F05.21150.21150.4 1.06E-05 14/114 K.IHNIDIPTTQQVPHIEALLK.R "sp|A6NHR9|SMHD1_HUMAN,tr|J3KTL8|J3KTL8_HUMAN" 2 2279.2638 2.05 71671 21150 4 2279.2603 570.8232 Structural maintenance of chromosomes flexible hinge domain-containing protein 1 OS=Homo sapiens OX=9606 GN=SMCHD1 PE=1 SV=2 5.99 3455.3 - 346698 - - - -1.5211 - 2.428 0.454 - 119.4 1 2 0 -0.0035 20 0 0 0 1.54E+07 7.52E+06 - - - 3.4732 1 221125_WJC_METTL3_EV_vs_WT_F05.21151.21151.3 2.42E-08 14/96 R.VAEELIFGTDHITTGASSDFDNATK.L "sp|Q96TA2|YMEL1_HUMAN,tr|Q96I63|Q96I63_HUMAN" 2 2638.2399 2.26 71672 21151 3 2638.242266 880.4206 ATP-dependent zinc metalloprotease YME1L1 OS=Homo sapiens OX=9606 GN=YME1L1 PE=1 SV=2 4.1 3455.4 - 284049 - - - 0.9135 - 3.325 0.604 - 144.1 1 2 0 0.0024 25 0 0 0 4.27E+06 1.89E+06 - - - 8.0375 0.9999 221125_WJC_METTL3_EV_vs_WT_F05.21154.21154.3 0.00192 Dec-64 R.ENSASQISQLEQQLSAK[136.11].N "sp|Q13948|CASP_HUMAN,sp|P39880|CUX1_HUMAN,tr|A0A2R8Y852|A0A2R8Y852_HUMAN,tr|A0A2R8YDI1|A0A2R8YDI1_HUMAN" 4 1867.9367 1.4 71673 21154 3 1867.934083 623.6528 Protein CASP OS=Homo sapiens OX=9606 GN=CUX1 PE=1 SV=2 4.53 3455.8 - 433060 - - - -1.393 - 2.199 0.46 - 124.6 1 2 0 -0.0026 17 0 0 0 1.99E+07 1.42E+07 - - - 5.6586 0.9962 221125_WJC_METTL3_EV_vs_WT_F05.21162.21162.3 8.33E-09 15/96 S.TNPAPGILGPPPPSFHLGGPAVGPR[166.11].G "sp|P43243|MATR3_HUMAN,tr|D6RE02|D6RE02_HUMAN,tr|B3KM87|B3KM87_HUMAN,tr|A8MXP9|A8MXP9_HUMAN,tr|D6RAY2|D6RAY2_HUMAN,tr|D6R991|D6R991_HUMAN,tr|A0A0R4J2E8|A0A0R4J2E8_HUMAN,tr|D6RAM9|D6RAM9_HUMAN,tr|D6RIA2|D6RIA2_HUMAN,tr|H0Y8T4|H0Y8T4_HUMAN,tr|D6REM6|D6REM6_HUMAN,tr|D6RBI2|D6RBI2_HUMAN" 12 2412.2942 1.76 71679 21162 3 2412.288278 805.1053 Matrin-3 OS=Homo sapiens OX=9606 GN=MATR3 PE=1 SV=2 9.44 3456.8 - 234198 - - - -2.4421 - 3.052 0.579 - 211.6 1 1 0 -0.0059 25 0 0 0 1.85E+07 1.05E+07 - - - 7.5607 1 221125_WJC_METTL3_EV_vs_WT_F05.21165.21165.3 9.20E-12 17/64 R.HVLLQEEVAELQGQVQR.T sp|Q6P4E1|GOLM2_HUMAN 1 1975.0487 1.48 71682 21165 3 1975.05355 659.3568 Protein GOLM2 OS=Homo sapiens OX=9606 GN=GOLM2 PE=1 SV=2 4.75 3457.1 - 171015 - - - 2.4612 - 3.937 0.641 - 478 1 2 0 0.0049 17 0 0 0 3.16E+06 2.13E+06 - - - 9.1473 0.9988 221125_WJC_METTL3_EV_vs_WT_F05.21170.21170.3 3.89E-11 18/96 K.AIGSSPLGSGEGLLGLSPGPNGHSH.L "sp|Q8IY67|RAVR1_HUMAN,tr|K7EQG2|K7EQG2_HUMAN,tr|E9PAU2|E9PAU2_HUMAN,tr|A0A087WZ13|A0A087WZ13_HUMAN" 4 2297.14 - 71685 21170 3 2297.138652 766.7206 Ribonucleoprotein PTB-binding 1 OS=Homo sapiens OX=9606 GN=RAVER1 PE=1 SV=1 5.99 3457.7 - 228309 - - - -0.5968 - 3.415 0.589 - 251.1 1 1 0 -0.0014 25 0 0 0 - - - - - 7.932 1 221125_WJC_METTL3_EV_vs_WT_F05.21173.21173.4 4.90E-08 22/108 K.K[136.11]ISSIQSIVPALEIANAHR[166.11].K "sp|P10809|CH60_HUMAN,tr|A0A7I2V2X6|A0A7I2V2X6_HUMAN,tr|A0A7I2YQK6|A0A7I2YQK6_HUMAN,tr|A0A7I2V599|A0A7I2V599_HUMAN,tr|A0A7I2YQ71|A0A7I2YQ71_HUMAN,tr|A0A7I2V5M1|A0A7I2V5M1_HUMAN,tr|A0A7I2V5K3|A0A7I2V5K3_HUMAN,tr|A0A7I2V369|A0A7I2V369_HUMAN" 8 2064.181 1.36 71687 21173 4 2064.176711 517.0525 "60 kDa heat shock protein, mitochondrial OS=Homo sapiens OX=9606 GN=HSPD1 PE=1 SV=2" 8.75 3458.1 - 3.68E+07 - - - -2.0987 - 3.954 0.619 - 489.2 1 2 0 -0.0043 19 0 0 0 1.44E+09 1.06E+09 - - - 5.0776 0.9888 221125_WJC_METTL3_EV_vs_WT_F05.21176.21176.2 4.21E-05 13/24 Q.SIVPALEIANAHR[166.11].K "sp|P10809|CH60_HUMAN,tr|A0A7I2V2X6|A0A7I2V2X6_HUMAN,tr|A0A7I2YQK6|A0A7I2YQK6_HUMAN,tr|A0A7I2V599|A0A7I2V599_HUMAN,tr|A0A7I2YQ71|A0A7I2YQ71_HUMAN,tr|A0A7I2V5M1|A0A7I2V5M1_HUMAN,tr|A0A7I2V5K3|A0A7I2V5K3_HUMAN,tr|A0A7I2V369|A0A7I2V369_HUMAN" 8 1399.7811 1.45 71689 21176 2 1399.779374 700.8978 "60 kDa heat shock protein, mitochondrial OS=Homo sapiens OX=9606 GN=HSPD1 PE=1 SV=2" 6.47 3458.4 - 463944 - - - -1.2459 - 2.389 0.45 - 561.6 1 1 0 -0.0017 13 0 0 0 2.85E+07 1.97E+07 - - - 4.5993 0.9935 221125_WJC_METTL3_EV_vs_WT_F05.21186.21186.3 0.0967 Aug-60 K.TQHGVLSQQFVELINK[136.11].C sp|Q12846|STX4_HUMAN 1 1847.9985 1.78 71696 21186 3 1847.995722 617.0068 Syntaxin-4 OS=Homo sapiens OX=9606 GN=STX4 PE=1 SV=2 6.41 3459.7 - 138917 - - - -1.5016 - 1.509 0.237 - 59.7 1 2 0 -0.0028 16 0 0 0 4.72E+06 2.65E+06 - - - 2.2373 0.9989 221125_WJC_METTL3_EV_vs_WT_F05.21192.21192.3 0.139 14/64 R.HLQLAIRGDEELDSLIK.A "sp|P0C0S5|H2AZ_HUMAN,sp|Q71UI9|H2AV_HUMAN,tr|C9J386|C9J386_HUMAN,tr|C9J0D1|C9J0D1_HUMAN,tr|A0A494C189|A0A494C189_HUMAN" 5 1949.0582 1.09 71699 21192 3 1949.061426 650.6933 Histone H2A.Z OS=Homo sapiens OX=9606 GN=H2AZ1 PE=1 SV=2 4.75 3460.6 - 306514 - - - 1.6598 - 2.626 0.343 - 221.2 1 2 1 0.0032 17 0 0 0 5.87E+06 5.41E+06 - - - 4.8023 1 221125_WJC_METTL3_EV_vs_WT_F05.21193.21193.3 7.65E-06 Dec-60 K.TQHGVLSQQFVELINK.C sp|Q12846|STX4_HUMAN 1 1839.9843 1.71 71700 21193 3 1839.984503 614.3354 Syntaxin-4 OS=Homo sapiens OX=9606 GN=STX4 PE=1 SV=2 6.41 3460.8 - 262984 - - - 0.112 - 2.454 0.524 - 172.4 1 2 0 0.0002 16 0 0 0 4.79E+06 2.80E+06 - - - 6.6855 0.9997 221125_WJC_METTL3_EV_vs_WT_F05.21194.21194.2 1.96E-06 22-Aug K.DAGTIAGLNVLR[166.11].L "sp|P11142|HSP7C_HUMAN,tr|E9PQQ4|E9PQQ4_HUMAN,tr|E9PKE3|E9PKE3_HUMAN,tr|E9PN89|E9PN89_HUMAN,tr|E9PLF4|E9PLF4_HUMAN,tr|E9PI65|E9PI65_HUMAN,tr|E9PK54|E9PK54_HUMAN,tr|E9PQK7|E9PQK7_HUMAN" 8 1208.6753 2.02 71701 21194 2 1208.67782 605.3449 Heat shock cognate 71 kDa protein OS=Homo sapiens OX=9606 GN=HSPA8 PE=1 SV=1 5.84 3460.9 - 215600 - - - 2.1213 - 2.105 0.519 - 188.1 1 2 0 0.0026 12 0 0 0 3.02E+07 1.50E+07 - - - 4.8319 1 221125_WJC_METTL3_EV_vs_WT_F05.21198.21198.3 1.31E-10 19/80 R.LASYLDKVQALEEANNDLENK.L sp|P35527|K1C9_HUMAN 1 2376.1809 579.23 71703 21198 3 2376.180989 793.0676 "Keratin, type I cytoskeletal 9 OS=Homo sapiens OX=9606 GN=KRT9 PE=1 SV=3" 4.18 3461.4 - 724348 - - - 0.0438 - 3.887 0.68 - 533 1 2 1 0.0001 21 0 0 0 5.63E+07 9.72E+04 - - - 9.3762 0.9979 221125_WJC_METTL3_EV_vs_WT_F05.21199.21199.3 0.00399 13/64 R.HLQLAIR[166.11]GDEELDSLIK[136.11].A "sp|P0C0S5|H2AZ_HUMAN,sp|Q71UI9|H2AV_HUMAN,tr|C9J386|C9J386_HUMAN,tr|C9J0D1|C9J0D1_HUMAN,tr|A0A494C189|A0A494C189_HUMAN" 5 1967.0807 1.09 71704 21199 3 1967.079479 656.7008 Histone H2A.Z OS=Homo sapiens OX=9606 GN=H2AZ1 PE=1 SV=2 4.75 3461.6 - 504584 - - - -0.6009 - 2.443 0.276 - 231.4 1 2 1 -0.0012 17 0 0 0 5.90E+06 5.41E+06 - - - 3.8734 0.9999 221125_WJC_METTL3_EV_vs_WT_F05.21200.21200.4 9.48E-08 22/162 K.SFEAPATINSASLHPEK[136.11]EFLVAGGEDFK[136.11].L sp|Q9Y3F4|STRAP_HUMAN 1 3006.4946 0.84 71705 21200 4 3006.492076 752.6309 Serine-threonine kinase receptor-associated protein OS=Homo sapiens OX=9606 GN=STRAP PE=1 SV=1 4.57 3461.7 - 855212 - - - -0.8289 - 3.252 0.566 - 142.1 1 2 1 -0.0025 28 0 0 0 7.84E+06 9.34E+06 - - - 4.5179 0.9997 221125_WJC_METTL3_EV_vs_WT_F05.21202.21202.3 3.65E-05 Dec-56 R.TK[136.11]EEALELINGYIQK[136.11].L "sp|Q13526|PIN1_HUMAN,tr|K7EMU7|K7EMU7_HUMAN,tr|K7EN45|K7EN45_HUMAN" 3 1763.964 1.55 71707 21202 3 1763.96378 588.9953 Peptidyl-prolyl cis-trans isomerase NIMA-interacting 1 OS=Homo sapiens OX=9606 GN=PIN1 PE=1 SV=1 4.78 3462 - 570292 - - - -0.1338 - 2.444 0.436 - 239.5 1 2 1 -0.0002 15 0 0 0 1.09E+07 7.02E+06 - - - 5.7327 0.9999 221125_WJC_METTL3_EV_vs_WT_F05.21203.21203.4 0.00444 19/114 K.IHNIDIPTTQQVPHIEALLK[136.11].R "sp|A6NHR9|SMHD1_HUMAN,tr|J3KTL8|J3KTL8_HUMAN" 2 2287.278 2.05 71708 21203 4 2287.275044 572.8268 Structural maintenance of chromosomes flexible hinge domain-containing protein 1 OS=Homo sapiens OX=9606 GN=SMCHD1 PE=1 SV=2 5.99 3462.1 - 501309 - - - -1.2779 - 2.413 0.424 - 209.7 1 2 0 -0.0029 20 0 0 0 1.54E+07 7.52E+06 - - - 3.2102 1 221125_WJC_METTL3_EV_vs_WT_F05.21208.21208.4 3.54E-10 23/162 K.SFEAPATINSASLHPEKEFLVAGGEDFK.L sp|Q9Y3F4|STRAP_HUMAN 1 2990.4662 0.84 71711 21208 4 2990.462023 748.6238 Serine-threonine kinase receptor-associated protein OS=Homo sapiens OX=9606 GN=STRAP PE=1 SV=1 4.57 3462.6 - 826972 - - - -1.3861 - 3.983 0.629 - 174.7 1 2 1 -0.0041 28 0 0 0 7.84E+06 9.34E+06 - - - 5.1288 1 221125_WJC_METTL3_EV_vs_WT_F05.21209.21209.4 1.77E-11 13/138 K.AVGYSC[160.03]MPSNKDEDGLVVLVFNKK.E sp|Q7Z3B4|NUP54_HUMAN 1 2669.3193 1.54 71712 21209 4 2669.319956 668.3371 Nucleoporin p54 OS=Homo sapiens OX=9606 GN=NUP54 PE=1 SV=2 6.15 3462.8 - 521812 - - - 0.242 - 2.739 0.643 - 92.7 1 2 1 0.0006 24 0 0 0 6.57E+06 4.26E+06 - - - 5.1459 0.9998 221125_WJC_METTL3_EV_vs_WT_F05.21210.21210.4 2.28E-06 11/138 K.AVGYSC[160.03]MPSNK[136.11]DEDGLVVLVFNK[136.11]K[136.11].E sp|Q7Z3B4|NUP54_HUMAN 1 2693.3619 1.54 71713 21210 4 2693.355907 674.3478 Nucleoporin p54 OS=Homo sapiens OX=9606 GN=NUP54 PE=1 SV=2 6.15 3462.9 - 404504 - - - -2.2288 - 2.329 0.553 - 86.9 1 2 1 -0.006 24 0 0 0 6.57E+06 4.26E+06 - - - 4.309 0.9994 221125_WJC_METTL3_EV_vs_WT_F05.21211.21211.4 0.000246 Nov-96 R.HLQLAIRGDEELDSLIK.A "sp|P0C0S5|H2AZ_HUMAN,sp|Q71UI9|H2AV_HUMAN,tr|C9J386|C9J386_HUMAN,tr|C9J0D1|C9J0D1_HUMAN,tr|A0A494C189|A0A494C189_HUMAN" 5 1949.0582 1.2 71714 21211 4 1949.054653 488.2718 Histone H2A.Z OS=Homo sapiens OX=9606 GN=H2AZ1 PE=1 SV=2 4.75 3463 - 192331 - - - -1.8152 - 2.276 0.413 - 128.4 1 2 1 -0.0035 17 0 0 0 2.39E+06 2.00E+06 - - - 3.1053 0.9996 221125_WJC_METTL3_EV_vs_WT_F05.21212.21212.4 0.00444 Dec-96 R.HLQLAIR[166.11]GDEELDSLIK[136.11].A "sp|P0C0S5|H2AZ_HUMAN,sp|Q71UI9|H2AV_HUMAN,tr|C9J386|C9J386_HUMAN,tr|C9J0D1|C9J0D1_HUMAN,tr|A0A494C189|A0A494C189_HUMAN" 5 1967.0807 1.18 71715 21212 4 1967.082111 492.7774 Histone H2A.Z OS=Homo sapiens OX=9606 GN=H2AZ1 PE=1 SV=2 4.75 3463.2 - 188184 - - - 0.7371 - 2.377 0.414 - 137 1 2 1 0.0014 17 0 0 0 2.37E+06 2.00E+06 - - - 3.1297 0.999 221125_WJC_METTL3_EV_vs_WT_F05.21213.21213.3 5.00E-05 Sep-76 R.NTNGSQFFITTVPTPHLDGK.H sp|Q08752|PPID_HUMAN 1 2173.0804 1.95 71716 21213 3 2173.073148 725.3674 Peptidyl-prolyl cis-trans isomerase D OS=Homo sapiens OX=9606 GN=PPID PE=1 SV=3 6.74 3463.3 - 160368 - - - -3.3294 - 1.861 0.404 - 73 1 2 0 -0.0072 20 0 0 0 1.10E+07 5.65E+06 - - - 4.549 1 221125_WJC_METTL3_EV_vs_WT_F05.21218.21218.3 4.13E-11 24/92 K.AYHEQLSVAEITNAC[160.03]FEPANQMVK[136.11].C "sp|Q6PEY2|TBA3E_HUMAN,sp|P0DPH7|TBA3C_HUMAN,sp|Q71U36|TBA1A_HUMAN,sp|P0DPH8|TBA3D_HUMAN,sp|P68366|TBA4A_HUMAN,sp|P68363|TBA1B_HUMAN,tr|C9JDS9|C9JDS9_HUMAN" 7 2757.2982 0.51 71719 21218 3 2757.292756 920.1067 Tubulin alpha-3E chain OS=Homo sapiens OX=9606 GN=TUBA3E PE=1 SV=2 4.75 3464 - 613155 - - - -1.9697 - 5.009 0.689 - 475.3 1 2 0 -0.0054 24 0 0 0 1.26E+07 2.46E+07 - - - 9.9624 1 221125_WJC_METTL3_EV_vs_WT_F05.21220.21220.4 4.28E-07 20/150 R.TGHILHPEYLQPLPSTPVSPIELDAK[136.11].K sp|Q96F45|ZN503_HUMAN 1 2859.5262 1.64 71721 21220 4 2859.523811 715.8888 Zinc finger protein 503 OS=Homo sapiens OX=9606 GN=ZNF503 PE=1 SV=1 5.26 3464.2 - 234204 - - - -0.8341 - 3.493 0.528 - 235 1 2 0 -0.0024 26 0 0 0 9.61E+07 5.87E+07 - - - 4.2156 0.9988 221125_WJC_METTL3_EV_vs_WT_F05.21222.21222.3 0.0157 Jun-76 K.IHNIDIPTTQQVPHIEALLK.R "sp|A6NHR9|SMHD1_HUMAN,tr|J3KTL8|J3KTL8_HUMAN" 2 2279.2638 2.53 71723 21222 3 2279.263338 760.7619 Structural maintenance of chromosomes flexible hinge domain-containing protein 1 OS=Homo sapiens OX=9606 GN=SMCHD1 PE=1 SV=2 5.99 3464.5 - 179926 - - - -0.1882 - 1.44 0.337 - 27 1 2 0 -0.0004 20 0 0 0 2.38E+06 9.39E+05 - - - 3.1817 1 221125_WJC_METTL3_EV_vs_WT_F05.21226.21226.3 3.08E-11 26/72 K.K[136.11]ISSIQSIVPALEIANAHR[166.11].K "sp|P10809|CH60_HUMAN,tr|A0A7I2V2X6|A0A7I2V2X6_HUMAN,tr|A0A7I2YQK6|A0A7I2YQK6_HUMAN,tr|A0A7I2V599|A0A7I2V599_HUMAN,tr|A0A7I2YQ71|A0A7I2YQ71_HUMAN,tr|A0A7I2V5M1|A0A7I2V5M1_HUMAN,tr|A0A7I2V5K3|A0A7I2V5K3_HUMAN,tr|A0A7I2V369|A0A7I2V369_HUMAN" 8 2064.181 1.32 71725 21226 3 2064.18096 689.0676 "60 kDa heat shock protein, mitochondrial OS=Homo sapiens OX=9606 GN=HSPD1 PE=1 SV=2" 8.75 3464.9 - 5.77E+06 - - - -0.0402 - 4.713 0.68 - 821.8 1 2 0 -0.0001 19 0 0 0 6.01E+08 4.54E+08 - - - 9.9301 1 221125_WJC_METTL3_EV_vs_WT_F05.21227.21227.4 9.87E-10 27/150 R.TGHILHPEYLQPLPSTPVSPIELDAK.K sp|Q96F45|ZN503_HUMAN 1 2851.512 1.64 71726 21227 4 2851.516826 713.8853 Zinc finger protein 503 OS=Homo sapiens OX=9606 GN=ZNF503 PE=1 SV=1 5.26 3465.1 - 638152 - - - 1.6938 - 4.632 0.591 - 431 1 2 0 0.0048 26 0 0 0 9.65E+07 5.89E+07 - - - 4.8523 1 221125_WJC_METTL3_EV_vs_WT_F05.21228.21228.3 0.0113 25/92 K.AYHEQLSVAEITNAC[160.03]FEPANQMVK.C "sp|Q6PEY2|TBA3E_HUMAN,sp|P0DPH7|TBA3C_HUMAN,sp|Q71U36|TBA1A_HUMAN,sp|P0DPH8|TBA3D_HUMAN,sp|P68366|TBA4A_HUMAN,sp|P68363|TBA1B_HUMAN,tr|C9JDS9|C9JDS9_HUMAN" 7 2749.284 0.51 71727 21228 3 2749.286509 917.4353 Tubulin alpha-3E chain OS=Homo sapiens OX=9606 GN=TUBA3E PE=1 SV=2 4.75 3465.2 - 703087 - - - 0.9173 - 5.131 0.706 - 638 1 2 0 0.0025 24 0 0 0 1.26E+07 2.46E+07 - - - 10.2087 1 221125_WJC_METTL3_EV_vs_WT_F05.21235.21235.3 6.87E-12 19/72 K.KISSIQSIVPALEIANAHR.K "sp|P10809|CH60_HUMAN,tr|A0A7I2V2X6|A0A7I2V2X6_HUMAN,tr|A0A7I2YQK6|A0A7I2YQK6_HUMAN,tr|A0A7I2V599|A0A7I2V599_HUMAN,tr|A0A7I2YQ71|A0A7I2YQ71_HUMAN,tr|A0A7I2V5M1|A0A7I2V5M1_HUMAN,tr|A0A7I2V5K3|A0A7I2V5K3_HUMAN,tr|A0A7I2V369|A0A7I2V369_HUMAN" 8 2046.1586 1.32 71733 21235 3 2046.159892 683.0601 "60 kDa heat shock protein, mitochondrial OS=Homo sapiens OX=9606 GN=HSPD1 PE=1 SV=2" 8.75 3466.1 - 4.61E+06 - - - 0.6446 - 3.941 0.647 - 421.4 1 2 0 0.0013 19 0 0 0 6.01E+08 4.54E+08 - - - 9.1224 1 221125_WJC_METTL3_EV_vs_WT_F05.21237.21237.2 6.05E-07 13/22 K.DAGTIAGLNVLR.L "sp|P11142|HSP7C_HUMAN,tr|E9PQQ4|E9PQQ4_HUMAN,tr|E9PKE3|E9PKE3_HUMAN,tr|E9PN89|E9PN89_HUMAN,tr|E9PLF4|E9PLF4_HUMAN,tr|E9PI65|E9PI65_HUMAN,tr|E9PK54|E9PK54_HUMAN,tr|E9PQK7|E9PQK7_HUMAN" 8 1198.667 2.2 71734 21237 2 1198.669114 600.3408 Heat shock cognate 71 kDa protein OS=Homo sapiens OX=9606 GN=HSPA8 PE=1 SV=1 5.84 3466.4 - 1.45E+06 - - - 1.7753 - 2.654 0.575 - 567.5 1 2 0 0.0021 12 0 0 0 3.30E+07 1.50E+07 - - - 5.8555 0.9998 221125_WJC_METTL3_EV_vs_WT_F05.21238.21238.3 0.0181 Aug-60 K.EEDAFHFVSYVPVNGR.L "sp|Q9Y5K5|UCHL5_HUMAN,tr|H0Y4E0|H0Y4E0_HUMAN,tr|Q5LJA9|Q5LJA9_HUMAN,tr|H0Y6Y4|H0Y6Y4_HUMAN,tr|Q5LJB0|Q5LJB0_HUMAN,tr|Q5LJA5|Q5LJA5_HUMAN" 6 1864.8744 1.5 71735 21238 3 1864.877679 622.6321 Ubiquitin carboxyl-terminal hydrolase isozyme L5 OS=Homo sapiens OX=9606 GN=UCHL5 PE=1 SV=3 4.65 3466.5 - 269466 - - - 1.7513 - 1.728 0.439 - 53.4 1 2 0 0.0033 16 0 0 0 3.17E+06 2.12E+06 - - - 4.8369 0.9915 221125_WJC_METTL3_EV_vs_WT_F05.21239.21239.3 0.0399 Sep-76 R.NTNGSQFFITTVPTPHLDGK[136.11].H sp|Q08752|PPID_HUMAN 1 2181.0946 1.95 71736 21239 3 2181.100682 728.0388 Peptidyl-prolyl cis-trans isomerase D OS=Homo sapiens OX=9606 GN=PPID PE=1 SV=3 6.74 3466.6 - 278592 - - - 2.7963 - 1.525 0.278 - 63.9 1 2 0 0.0061 20 0 0 0 1.10E+07 5.65E+06 - - - 2.6615 0.9994 221125_WJC_METTL3_EV_vs_WT_F05.21244.21244.2 5.47E-05 30-Jul K.VLAQNSGFDLQETLVK[136.11].L sp|P40227|TCPZ_HUMAN 1 1768.9451 0.18 71741 21244 2 1768.948458 885.4798 T-complex protein 1 subunit zeta OS=Homo sapiens OX=9606 GN=CCT6A PE=1 SV=3 4.37 3467.3 - 68161.2 - - - 1.9181 - 1.584 0.49 - 85.7 1 2 0 0.0034 16 0 0 0 8.33E+04 4.62E+05 - - - 3.7899 0.9999 221125_WJC_METTL3_EV_vs_WT_F05.21247.21247.4 3.54E-05 14/84 K.FGHEFLEFEFR[166.11]PDGK[136.11].L "sp|Q96A72|MGN2_HUMAN,sp|P61326|MGN_HUMAN,tr|F5H6N1|F5H6N1_HUMAN" 3 1871.8962 2.46 71742 21247 4 1871.900403 468.9813 Protein mago nashi homolog 2 OS=Homo sapiens OX=9606 GN=MAGOHB PE=1 SV=1 4.83 3467.7 - 320774 - - - 2.2699 - 2.679 0.499 - 191.9 1 2 0 0.0042 15 0 0 0 8.63E+06 3.50E+06 - - - 3.9207 0.9999 221125_WJC_METTL3_EV_vs_WT_F05.21251.21251.3 2.33E-06 Sep-64 R.K[136.11]DDPLTNLNTAFDVAEK[136.11].Y "sp|P12814|ACTN1_HUMAN,tr|A0A804HJN7|A0A804HJN7_HUMAN,tr|A0A804HK61|A0A804HK61_HUMAN,tr|G3V2W4|G3V2W4_HUMAN,tr|A0A804HJU8|A0A804HJU8_HUMAN,tr|A0A804HIN7|A0A804HIN7_HUMAN,tr|H9KV75|H9KV75_HUMAN,tr|A0A804HLF4|A0A804HLF4_HUMAN,tr|A0A7I2V4Y4|A0A7I2V4Y4_HUMAN,tr|A0A804HII9|A0A804HII9_HUMAN,tr|A0A804HL31|A0A804HL31_HUMAN,tr|A0A804HJQ9|A0A804HJQ9_HUMAN,tr|A0A804HKE2|A0A804HKE2_HUMAN,tr|G3V2N5|G3V2N5_HUMAN,tr|A0A804HLD0|A0A804HLD0_HUMAN" 15 1905.9655 0.97 71746 21251 3 1905.971004 636.3291 Alpha-actinin-1 OS=Homo sapiens OX=9606 GN=ACTN1 PE=1 SV=2 4.23 3468.2 - 113618 - - - 2.9025 - 2.134 0.512 - 79.6 1 2 0 0.0055 17 0 0 0 2.89E+06 2.98E+06 - - - 6.1617 1 221125_WJC_METTL3_EV_vs_WT_F05.21253.21253.2 1.53E-08 30-Sep R.SSSFSSWDDSSDSYWK[136.11].K sp|Q9NP61|ARFG3_HUMAN 1 1877.7472 0.98 71748 21253 2 1877.745462 939.8809 ADP-ribosylation factor GTPase-activating protein 3 OS=Homo sapiens OX=9606 GN=ARFGAP3 PE=1 SV=1 3.93 3468.5 - 70634.7 - - - -0.9005 - 2.324 0.739 - 231.4 1 2 0 -0.0017 16 0 0 0 8.26E+05 8.42E+05 - - - 6.572 0.9194 221125_WJC_METTL3_EV_vs_WT_F05.21258.21258.3 0.00651 Oct-56 K.TLNDMRQEYEQLIAK.N "sp|P35527|K1C9_HUMAN,tr|K7EQQ3|K7EQQ3_HUMAN" 2 1850.9196 59.77 71751 21258 3 1850.93154 617.9805 "Keratin, type I cytoskeletal 9 OS=Homo sapiens OX=9606 GN=KRT9 PE=1 SV=3" 4.68 3469.2 - 532164 - - - 6.4249 - 1.74 0.352 - 78.9 1 2 1 0.0119 15 0 0 0 1.88E+07 3.15E+05 - - - 3.9064 0.9993 221125_WJC_METTL3_EV_vs_WT_F05.21259.21259.4 3.40E-06 13/114 R.FK[136.11]K[136.11]EDEIPETVSLEMLDAAK[136.11].N "sp|Q96A26|F162A_HUMAN,tr|F8W7Q4|F8W7Q4_HUMAN,tr|E9PH05|E9PH05_HUMAN" 3 2316.1985 0.81 71752 21259 4 2316.206287 580.0569 Protein FAM162A OS=Homo sapiens OX=9606 GN=FAM162A PE=1 SV=2 4.36 3469.3 - 492776 - - - 3.3551 - 2.558 0.486 - 150 1 2 1 0.0078 20 0 0 0 3.42E+06 4.22E+06 - - - 3.768 1 221125_WJC_METTL3_EV_vs_WT_F05.21260.21260.3 4.62E-10 23/100 R.TGHILHPEYLQPLPSTPVSPIELDAK.K sp|Q96F45|ZN503_HUMAN 1 2851.512 1.58 71753 21260 3 2851.521546 951.5113 Zinc finger protein 503 OS=Homo sapiens OX=9606 GN=ZNF503 PE=1 SV=1 5.26 3469.4 - 407234 - - - 3.3491 - 4.603 0.685 - 471.8 1 2 0 0.0095 26 0 0 0 1.32E+07 8.34E+06 - - - 9.6868 1 221125_WJC_METTL3_EV_vs_WT_F05.21266.21266.2 2.23E-07 30-Aug R.SSSFSSWDDSSDSYWK.K sp|Q9NP61|ARFG3_HUMAN 1 1869.733 0.98 71759 21266 2 1869.738543 935.8738 ADP-ribosylation factor GTPase-activating protein 3 OS=Homo sapiens OX=9606 GN=ARFGAP3 PE=1 SV=1 3.93 3470.2 - 110924 - - - 2.9897 - 2.099 0.699 - 160.4 1 2 0 0.0056 16 0 0 0 8.26E+05 8.42E+05 - - - 6.025 0.9427 221125_WJC_METTL3_EV_vs_WT_F05.21267.21267.3 0.00227 Aug-84 R.SKDEAEALYQTKYQELQITAGR.H sp|Q7Z794|K2C1B_HUMAN 1 2541.2711 999 71760 21267 3 2542.271806 848.0976 "Keratin, type II cytoskeletal 1b OS=Homo sapiens OX=9606 GN=KRT77 PE=1 SV=3" 4.87 3470.4 - 97673.1 - - - 393.7829 - 1.856 0.375 - 67.2 1 2 2 1.0007 22 0 0 0 9.49E+05 0.00E+00 - - - 3.9099 1 221125_WJC_METTL3_EV_vs_WT_F05.21268.21268.2 1.99E-08 Dec-32 R.AETEC[160.03]QNTEYQQLLDIK.L "sp|P13645|K1C10_HUMAN,tr|A0A1B0GVI3|A0A1B0GVI3_HUMAN" 2 2081.9576 -1 71761 21268 2 2082.949331 1041.9861 "Keratin, type I cytoskeletal 10 OS=Homo sapiens OX=9606 GN=KRT10 PE=1 SV=6" 4 3470.5 - 93658.1 - - - 476.3695 - 2.674 0.675 - 527.7 1 2 0 0.9918 17 0 0 0 0.00E+00 0.00E+00 - - - 6.1333 0.9941 221125_WJC_METTL3_EV_vs_WT_F05.21273.21273.3 3.08E-09 13/64 R.AETEC[160.03]QNTEYQQLLDIK.L "sp|P13645|K1C10_HUMAN,tr|A0A1B0GVI3|A0A1B0GVI3_HUMAN" 2 2081.9576 999 71764 21273 3 2082.951343 694.9931 "Keratin, type I cytoskeletal 10 OS=Homo sapiens OX=9606 GN=KRT10 PE=1 SV=6" 4 3471.2 - 583866 - - - 477.3359 - 2.634 0.591 - 262.5 1 2 0 0.9938 17 0 0 0 1.89E+06 0.00E+00 - - - 7.3005 0.9999 221125_WJC_METTL3_EV_vs_WT_F05.21274.21274.3 8.74E-08 17/48 R.KVESLQEEIAFLK.K "sp|P08670|VIME_HUMAN,tr|B0YJC5|B0YJC5_HUMAN,tr|B0YJC4|B0YJC4_HUMAN" 3 1532.845 0.07 71765 21274 3 1532.85005 511.9556 Vimentin OS=Homo sapiens OX=9606 GN=VIM PE=1 SV=4 4.79 3471.3 - 1.32E+06 - - - 3.288 - 3.264 0.536 - 734.6 1 2 0 0.005 13 0 0 0 1.29E+07 1.75E+08 - - - 7.7218 0.9765 221125_WJC_METTL3_EV_vs_WT_F05.21275.21275.4 0.0114 13/108 K.VTYRPLDPDNYDKDLSFIK.V sp|O60825|F262_HUMAN 1 2298.1532 4.42 71766 21275 4 2298.162956 575.5456 "6-phosphofructo-2-kinase\fructose-2,6-bisphosphatase 2 OS=Homo sapiens OX=9606 GN=PFKFB2 PE=1 SV=2" 4.58 3471.4 - 676795 - - - 4.2395 - 2.236 0.306 - 91.9 1 2 1 0.0097 19 0 0 0 1.64E+07 3.70E+06 - - - 2.1589 0.9998 221125_WJC_METTL3_EV_vs_WT_F05.21281.21281.3 0.000333 Nov-52 K.AAILPTSIFLTNKK.G "sp|O14744|ANM5_HUMAN,tr|H0YJX6|H0YJX6_HUMAN" 2 1515.9025 2.95 71772 21281 3 1515.906725 506.3081 Protein arginine N-methyltransferase 5 OS=Homo sapiens OX=9606 GN=PRMT5 PE=1 SV=4 10 3472.2 - 195053 - - - 2.8102 - 2.43 0.453 - 195.9 1 2 0 0.0043 14 0 0 0 2.00E+06 6.77E+05 - - - 5.9489 0.9995 221125_WJC_METTL3_EV_vs_WT_F05.21285.21285.3 0.0216 Jul-64 R.KDDPLTNLNTAFDVAEK.Y "sp|P12814|ACTN1_HUMAN,tr|A0A804HJN7|A0A804HJN7_HUMAN,tr|A0A804HK61|A0A804HK61_HUMAN,tr|G3V2W4|G3V2W4_HUMAN,tr|A0A804HJU8|A0A804HJU8_HUMAN,tr|A0A804HIN7|A0A804HIN7_HUMAN,tr|H9KV75|H9KV75_HUMAN,tr|A0A804HLF4|A0A804HLF4_HUMAN,tr|A0A7I2V4Y4|A0A7I2V4Y4_HUMAN,tr|A0A804HII9|A0A804HII9_HUMAN,tr|A0A804HL31|A0A804HL31_HUMAN,tr|A0A804HJQ9|A0A804HJQ9_HUMAN,tr|A0A804HKE2|A0A804HKE2_HUMAN,tr|G3V2N5|G3V2N5_HUMAN,tr|A0A804HLD0|A0A804HLD0_HUMAN" 15 1889.9371 0.97 71776 21285 3 1889.941885 630.9863 Alpha-actinin-1 OS=Homo sapiens OX=9606 GN=ACTN1 PE=1 SV=2 4.23 3472.7 - 156802 - - - 2.5466 - 1.622 0.436 - 60 1 2 0 0.0048 17 0 0 0 2.89E+06 2.98E+06 - - - 4.6215 0.9982 221125_WJC_METTL3_EV_vs_WT_F05.21288.21288.3 2.01E-05 20/100 Q.STNPAPGILGPPPPSFHLGGPAVGPR.G "sp|P43243|MATR3_HUMAN,tr|D6RE02|D6RE02_HUMAN,tr|B3KM87|B3KM87_HUMAN,tr|A8MXP9|A8MXP9_HUMAN,tr|D6RAY2|D6RAY2_HUMAN,tr|D6R991|D6R991_HUMAN,tr|A0A0R4J2E8|A0A0R4J2E8_HUMAN,tr|D6RAM9|D6RAM9_HUMAN,tr|D6RIA2|D6RIA2_HUMAN,tr|H0Y8T4|H0Y8T4_HUMAN,tr|D6REM6|D6REM6_HUMAN,tr|D6RBI2|D6RBI2_HUMAN" 12 2489.3179 2.08 71778 21288 3 2489.321098 830.7799 Matrin-3 OS=Homo sapiens OX=9606 GN=MATR3 PE=1 SV=2 9.49 3473.1 - 583162 - - - 1.2734 - 3.26 0.577 - 348.1 1 1 0 0.0032 26 0 0 0 3.71E+06 1.79E+06 - - - 7.6908 1 221125_WJC_METTL3_EV_vs_WT_F05.21290.21290.3 4.72E-07 15/64 R.VEAVNMAEGIIHDTETK[136.11].M "sp|P38646|GRP75_HUMAN,tr|A0A7I2V2S7|A0A7I2V2S7_HUMAN,tr|A0A7I2V2G2|A0A7I2V2G2_HUMAN,tr|A0A7I2V3F7|A0A7I2V3F7_HUMAN,tr|A0A7I2YQB2|A0A7I2YQB2_HUMAN,tr|D6RCD7|D6RCD7_HUMAN" 6 1863.9128 0.39 71779 21290 3 1863.915305 622.3115 "Stress-70 protein, mitochondrial OS=Homo sapiens OX=9606 GN=HSPA9 PE=1 SV=2" 4.4 3473.3 - 1.81E+06 - - - 1.3558 - 2.986 0.575 - 235.3 1 2 0 0.0025 17 0 0 0 9.65E+06 2.46E+07 - - - 7.7136 1 221125_WJC_METTL3_EV_vs_WT_F05.21291.21291.2 4.96E-06 14/22 K.WELLQQVDTSTR.T sp|P04264|K2C1_HUMAN 1 1474.7416 459.51 71780 21291 2 1474.740886 738.3781 "Keratin, type II cytoskeletal 1 OS=Homo sapiens OX=9606 GN=KRT1 PE=1 SV=6" 4.37 3473.4 - 1.41E+06 - - - -0.4889 - 2.653 0.584 - 692.7 1 2 0 -0.0007 12 0 0 0 3.25E+07 7.06E+04 - - - 5.9214 0.9949 221125_WJC_METTL3_EV_vs_WT_F05.21295.21295.3 0.0067 Jun-76 R.FK[136.11]K[136.11]EDEIPETVSLEMLDAAK[136.11].N "sp|Q96A26|F162A_HUMAN,tr|F8W7Q4|F8W7Q4_HUMAN,tr|E9PH05|E9PH05_HUMAN" 3 2316.1985 1.57 71784 21295 3 2316.193735 773.0734 Protein FAM162A OS=Homo sapiens OX=9606 GN=FAM162A PE=1 SV=2 4.36 3474 - 207837 - - - -2.0642 - 1.738 0.342 - 36.8 1 2 1 -0.0048 20 0 0 0 3.17E+06 2.02E+06 - - - 3.6926 1 221125_WJC_METTL3_EV_vs_WT_F05.21301.21301.3 3.13E-08 15/80 K.TAEELMNFSK[136.11]GEENLMDAQVK[136.11].A "sp|P50990|TCPQ_HUMAN,tr|H7C4C8|H7C4C8_HUMAN" 2 2399.132 0.65 71788 21301 3 2399.129774 800.7179 T-complex protein 1 subunit theta OS=Homo sapiens OX=9606 GN=CCT8 PE=1 SV=4 4.25 3474.8 - 376771 - - - -0.912 - 3.27 0.624 - 231.4 1 2 1 -0.0022 21 0 0 0 1.91E+06 2.93E+06 - - - 8.3369 0.9998 221125_WJC_METTL3_EV_vs_WT_F05.21304.21304.3 4.66E-05 Sep-44 K.WELLQQVDTSTR.T sp|P04264|K2C1_HUMAN 1 1474.7416 999 71791 21304 3 1474.745065 492.5878 "Keratin, type II cytoskeletal 1 OS=Homo sapiens OX=9606 GN=KRT1 PE=1 SV=6" 4.37 3475.1 - 142562 - - - 2.3448 - 2.012 0.458 - 175.5 1 2 0 0.0035 12 0 0 0 1.45E+06 0.00E+00 - - - 5.5832 1 221125_WJC_METTL3_EV_vs_WT_F05.21310.21310.3 2.60E-09 19/100 R.TGHILHPEYLQPLPSTPVSPIELDAK[136.11].K sp|Q96F45|ZN503_HUMAN 1 2859.5262 1.58 71795 21310 3 2859.527319 954.1827 Zinc finger protein 503 OS=Homo sapiens OX=9606 GN=ZNF503 PE=1 SV=1 5.26 3476 - 457982 - - - 0.3927 - 3.516 0.608 - 303.3 1 2 0 0.0011 26 0 0 0 1.32E+07 8.34E+06 - - - 8.2109 1 221125_WJC_METTL3_EV_vs_WT_F05.21313.21313.4 9.79E-07 22/168 K.VLTQGINTPPVLVHNQLVLTPSIVTTNK[136.11]K[136.11].L sp|Q96T58|MINT_HUMAN 1 3139.8304 1.35 71798 21313 4 3139.832281 785.9649 Msx2-interacting protein OS=Homo sapiens OX=9606 GN=SPEN PE=1 SV=1 10 3476.4 - 411324 - - - 0.6086 - 3.655 0.616 - 247.7 1 2 0 0.0019 29 0 0 0 6.49E+06 4.80E+06 - - - 4.9866 1 221125_WJC_METTL3_EV_vs_WT_F05.21314.21314.3 3.38E-05 25/100 Q.STNPAPGILGPPPPSFHLGGPAVGPR[166.11].G "sp|P43243|MATR3_HUMAN,tr|D6RE02|D6RE02_HUMAN,tr|B3KM87|B3KM87_HUMAN,tr|A8MXP9|A8MXP9_HUMAN,tr|D6RAY2|D6RAY2_HUMAN,tr|D6R991|D6R991_HUMAN,tr|A0A0R4J2E8|A0A0R4J2E8_HUMAN,tr|D6RAM9|D6RAM9_HUMAN,tr|D6RIA2|D6RIA2_HUMAN,tr|H0Y8T4|H0Y8T4_HUMAN,tr|D6REM6|D6REM6_HUMAN,tr|D6RBI2|D6RBI2_HUMAN" 12 2499.3262 2.16 71799 21314 3 2499.325583 834.116 Matrin-3 OS=Homo sapiens OX=9606 GN=MATR3 PE=1 SV=2 9.49 3476.5 - 385184 - - - -0.2461 - 4.249 0.603 - 613.4 1 1 0 -0.0006 26 0 0 0 6.76E+07 3.14E+07 - - - 8.591 0.999 221125_WJC_METTL3_EV_vs_WT_F05.21318.21318.3 0.0229 Aug-96 R.FEPC[160.03]SSSYLPLRPSEGFPNYC[160.03]TPPR.R sp|Q5T749|KPRP_HUMAN 1 2957.3477 999 71803 21318 3 2957.351236 986.7898 Keratinocyte proline-rich protein OS=Homo sapiens OX=9606 GN=KPRP PE=1 SV=1 6.13 3477 - 209218 - - - 1.2126 - 1.578 0.348 - 37.6 1 2 0 0.0036 25 0 0 0 3.20E+06 0.00E+00 - - - 3.4683 0.9948 221125_WJC_METTL3_EV_vs_WT_F05.21321.21321.3 5.76E-06 Oct-92 R.SR[166.11]PPEER[166.11]PPGLPLPPPPPSSSAVF.R sp|P48634|PRC2A_HUMAN 1 2527.3338 1.46 71805 21321 3 2527.334729 843.4519 Protein PRRC2A OS=Homo sapiens OX=9606 GN=PRRC2A PE=1 SV=3 5.86 3477.4 - 353579 - - - 0.368 - 2.16 0.501 - 41.8 1 1 0 0.0009 24 0 0 0 1.26E+07 8.64E+06 - - - 5.914 1 221125_WJC_METTL3_EV_vs_WT_F05.21323.21323.3 8.28E-06 19/72 K.ESSHSGVVLSVEEVEAGLK.G "sp|Q9NRA8|4ET_HUMAN,tr|B1AKL4|B1AKL4_HUMAN,tr|B0QYZ7|B0QYZ7_HUMAN" 3 1954.9848 1.21 71806 21323 3 1954.984369 652.6689 Eukaryotic translation initiation factor 4E transporter OS=Homo sapiens OX=9606 GN=EIF4ENIF1 PE=1 SV=2 4.48 3477.6 - 1.29E+06 - - - -0.1954 - 3.386 0.501 - 592.3 1 2 0 -0.0004 19 0 0 0 5.44E+07 4.48E+07 - - - 7.122 1 221125_WJC_METTL3_EV_vs_WT_F05.21324.21324.3 3.48E-08 17/72 K.ESSHSGVVLSVEEVEAGLK[136.11].G "sp|Q9NRA8|4ET_HUMAN,tr|B1AKL4|B1AKL4_HUMAN,tr|B0QYZ7|B0QYZ7_HUMAN" 3 1962.999 1.21 71807 21324 3 1962.998402 655.3403 Eukaryotic translation initiation factor 4E transporter OS=Homo sapiens OX=9606 GN=EIF4ENIF1 PE=1 SV=2 4.48 3477.7 - 1.38E+06 - - - -0.2797 - 3.206 0.59 - 441.9 1 2 0 -0.0005 19 0 0 0 5.44E+07 4.48E+07 - - - 7.98 1 221125_WJC_METTL3_EV_vs_WT_F05.21327.21327.4 3.04E-05 22/168 K.VLTQGINTPPVLVHNQLVLTPSIVTTNKK.L sp|Q96T58|MINT_HUMAN 1 3123.802 1.35 71810 21327 4 3123.80776 781.9578 Msx2-interacting protein OS=Homo sapiens OX=9606 GN=SPEN PE=1 SV=1 10 3478.1 - 2.23E+06 - - - 1.8535 - 3.03 0.506 - 166.5 1 2 0 0.0058 29 0 0 0 6.49E+06 4.80E+06 - - - 3.9703 0.9997 221125_WJC_METTL3_EV_vs_WT_F05.21328.21328.2 0.00135 16-Aug K.LLQDFFNGK[136.11].E "sp|P54652|HSP72_HUMAN,sp|P11142|HSP7C_HUMAN,sp|P17066|HSP76_HUMAN,tr|E9PNE6|E9PNE6_HUMAN,tr|A8K7Q2|A8K7Q2_HUMAN,tr|E9PKE3|E9PKE3_HUMAN,tr|E9PN89|E9PN89_HUMAN" 7 1088.5746 0.53 71811 21328 2 1088.574812 545.2946 Heat shock-related 70 kDa protein 2 OS=Homo sapiens OX=9606 GN=HSPA2 PE=1 SV=1 5.84 3478.2 - 579853 - - - 0.1993 - 1.65 0.409 - 172.2 1 2 0 0.0002 9 0 0 0 8.11E+06 1.52E+07 - - - 3.5106 0.9999 221125_WJC_METTL3_EV_vs_WT_F05.21330.21330.4 2.39E-11 22/108 K.VSSLPFSVEALMSDKKPPK.E "sp|P35548|MSX2_HUMAN,tr|D6RIS4|D6RIS4_HUMAN" 2 2059.1024 0.82 71813 21330 4 2059.101477 515.7829 Homeobox protein MSX-2 OS=Homo sapiens OX=9606 GN=MSX2 PE=1 SV=3 8.47 3478.5 - 425647 - - - -0.4308 - 3.858 0.591 - 358.2 1 2 1 -0.0009 19 0 0 0 4.44E+06 5.38E+06 - - - 4.8265 1 221125_WJC_METTL3_EV_vs_WT_F05.21331.21331.3 1.09E-06 13/88 R.FFAQSQSLTPSPGWQSLGSSQSR.L "sp|Q8NDV7|TNR6A_HUMAN,tr|H7C269|H7C269_HUMAN" 2 2482.1877 2.58 71814 21331 3 2482.189822 828.4032 Trinucleotide repeat-containing gene 6A protein OS=Homo sapiens OX=9606 GN=TNRC6A PE=1 SV=2 9.75 3478.6 - 347178 - - - 0.8545 - 2.745 0.562 - 151.1 1 2 0 0.0021 23 0 0 0 4.14E+06 1.61E+06 - - - 7.174 0.9997 221125_WJC_METTL3_EV_vs_WT_F05.21332.21332.4 1.02E-05 9/108 K.GTYIHALDNGLFTLGAPHK[136.11].E "sp|Q14331|FRG1_HUMAN,tr|E9PRR7|E9PRR7_HUMAN" 2 2032.0622 1.28 71815 21332 4 2032.062649 509.0228 Protein FRG1 OS=Homo sapiens OX=9606 GN=FRG1 PE=1 SV=1 6.92 3478.7 - 220318 - - - 0.2406 - 2.137 0.362 - 56.5 1 2 0 0.0005 19 0 0 0 3.84E+06 3.00E+06 - - - 2.6336 0.9999 221125_WJC_METTL3_EV_vs_WT_F05.21342.21342.4 6.37E-06 8/108 K.GTYIHALDNGLFTLGAPHK.E "sp|Q14331|FRG1_HUMAN,tr|E9PRR7|E9PRR7_HUMAN" 2 2024.048 1.22 71823 21342 4 2024.051382 507.0193 Protein FRG1 OS=Homo sapiens OX=9606 GN=FRG1 PE=1 SV=1 6.92 3480 - 296553 - - - 1.6907 - 2.003 0.459 - 42.7 1 2 0 0.0034 19 0 0 0 3.79E+06 3.10E+06 - - - 3.4552 0.9998 221125_WJC_METTL3_EV_vs_WT_F05.21343.21343.4 2.29E-06 11/132 K.LTSLAAALDENKDGKVNIDDLVK.V sp|O95202|LETM1_HUMAN 1 2441.3013 1.22 71824 21343 4 2441.305803 611.3326 Mitochondrial proton\calcium exchanger protein OS=Homo sapiens OX=9606 GN=LETM1 PE=1 SV=1 4.36 3480.2 - 243497 - - - 1.8306 - 2.537 0.515 - 62.6 1 2 2 0.0045 23 0 0 0 2.99E+06 2.45E+06 - - - 4.0089 0.9999 221125_WJC_METTL3_EV_vs_WT_F05.21353.21353.4 0.0537 16/132 K.LTSLAAALDENK[136.11]DGK[136.11]VNIDDLVK[136.11].V sp|O95202|LETM1_HUMAN 1 2465.3439 1.22 71832 21353 4 2465.3445 617.3433 Mitochondrial proton\calcium exchanger protein OS=Homo sapiens OX=9606 GN=LETM1 PE=1 SV=1 4.36 3481.5 - 272968 - - - 0.2296 - 3.1 0.493 - 134.8 1 2 2 0.0006 23 0 0 0 2.99E+06 2.45E+06 - - - 3.8835 1 221125_WJC_METTL3_EV_vs_WT_F05.21360.21360.4 5.80E-07 16/126 K.LSEPKPIFFNLNIAAAKPTPPK.S "sp|P18583|SON_HUMAN,tr|H7C1M2|H7C1M2_HUMAN,tr|H7C2G8|H7C2G8_HUMAN,tr|J3QSZ5|J3QSZ5_HUMAN" 4 2392.3519 1.66 71835 21360 4 2392.351005 599.0952 Protein SON OS=Homo sapiens OX=9606 GN=SON PE=1 SV=4 9.7 3482.5 - 451553 - - - -0.3549 - 3.055 0.523 - 163 1 2 0 -0.0008 22 0 0 0 1.47E+07 8.90E+06 - - - 4.1434 1 221125_WJC_METTL3_EV_vs_WT_F05.21362.21362.2 1.92E-10 17/38 K.GNPQGFNQGLDC[160.03]DVIVAEVR[166.11].S sp|Q86U44|MTA70_HUMAN 1 2197.0461 0.01 71837 21362 2 2198.038122 1099.5303 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 4.03 3482.8 - 251992 - - - 451.509 - 3.148 0.686 - 702.8 1 2 0 0.992 20 0 0 0 5.56E+06 5.09E+08 - - - 6.6157 0.9999 221125_WJC_METTL3_EV_vs_WT_F05.21368.21368.3 6.22E-08 13/60 K.K[136.11]VSQEILELLNTTTAK[136.11].E "sp|Q86U44|MTA70_HUMAN,tr|H0YFV6|H0YFV6_HUMAN" 2 1803.0324 0 71841 21368 3 1803.025343 602.0181 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 6.14 3483.5 - 389494 - - - -3.9306 - 2.745 0.562 - 297.4 1 2 0 -0.0071 16 0 0 0 6.72E+04 1.95E+07 - - - 7.3947 0.9968 221125_WJC_METTL3_EV_vs_WT_F05.21373.21373.3 6.29E-07 17/52 Q.LDGIHLLDPDVVAR[166.11].F sp|Q86U44|MTA70_HUMAN 1 1541.8441 0 71844 21373 3 1541.841209 514.9553 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 4.41 3484.2 - 442733 - - - -1.8828 - 2.885 0.524 - 523.3 1 1 0 -0.0029 14 0 0 0 3.19E+04 3.91E+07 - - - 7.197 1 221125_WJC_METTL3_EV_vs_WT_F05.21389.21389.4 4.81E-11 21/108 L.ILHDDEVTVTEDK[136.11]INALIK[136.11].A sp|P05386|RLA1_HUMAN 1 2181.1864 1.9 71855 21389 4 2181.185108 546.3039 60S acidic ribosomal protein P1 OS=Homo sapiens OX=9606 GN=RPLP1 PE=1 SV=1 4.43 3486.3 - 278986 - - - -0.5758 - 3.261 0.629 - 408.4 1 1 1 -0.0013 19 0 0 0 1.51E+07 7.91E+06 - - - 5.1003 0.998 221125_WJC_METTL3_EV_vs_WT_F05.21394.21394.3 1.18E-10 16/68 T.GTQDQIQNAQYLLQNSVK.Q sp|P61978|HNRPK_HUMAN 1 2047.0334 1.34 71858 21394 3 2047.029734 683.3518 Heterogeneous nuclear ribonucleoprotein K OS=Homo sapiens OX=9606 GN=HNRNPK PE=1 SV=1 5.83 3487 - 512311 - - - -1.807 - 2.999 0.598 - 350.7 1 1 0 -0.0037 18 0 0 0 3.00E+07 2.24E+07 - - - 7.9409 1 221125_WJC_METTL3_EV_vs_WT_F05.21404.21404.3 6.81E-08 15/88 K.FNEEHIPDSPFVVPVASPSGDAR[166.11].R "sp|P21333|FLNA_HUMAN,tr|A0A7P0NMY4|A0A7P0NMY4_HUMAN,tr|Q60FE5|Q60FE5_HUMAN,tr|H0Y5C6|H0Y5C6_HUMAN" 4 2476.1898 2.06 71864 21404 3 2476.183657 826.4039 Filamin-A OS=Homo sapiens OX=9606 GN=FLNA PE=1 SV=4 4.31 3488.2 - 593571 - - - -2.4901 - 3.301 0.58 - 149.4 1 2 0 -0.0062 23 0 0 0 4.82E+07 2.35E+07 - - - 7.8063 1 221125_WJC_METTL3_EV_vs_WT_F05.21419.21419.3 1.54E-10 17/76 R.NSVQHQFQDTFPGPYAVLTK.D sp|Q14774|HLX_HUMAN 1 2276.1226 1.25 71871 21419 3 2276.117002 759.7148 H2.0-like homeobox protein OS=Homo sapiens OX=9606 GN=HLX PE=1 SV=3 6.74 3490.1 - 1.02E+06 - - - -2.4515 - 2.927 0.63 - 203.5 1 2 0 -0.0056 20 0 0 0 3.66E+07 2.94E+07 - - - 8.1678 0.9931 221125_WJC_METTL3_EV_vs_WT_F05.21421.21421.3 6.28E-10 16/76 K.GNPQGFNQGLDC[160.03]DVIVAEVR.S sp|Q86U44|MTA70_HUMAN 1 2187.0379 0.01 71873 21421 3 2188.029753 730.0199 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 4.03 3490.2 - 2.78E+06 - - - 453.5299 - 2.739 0.638 - 283.7 1 2 0 0.9919 20 0 0 0 5.38E+07 3.85E+09 - - - 7.8228 0.9998 221125_WJC_METTL3_EV_vs_WT_F05.21427.21427.3 0.000126 20/84 K.VGR[166.11]PSNIGQAQPIIDQLAEEAR[166.11].A "sp|Q9UHX1|PUF60_HUMAN,tr|A0A0J9YYL3|A0A0J9YYL3_HUMAN,tr|A0A0J9YWM1|A0A0J9YWM1_HUMAN,tr|H0YEM1|H0YEM1_HUMAN,tr|E9PMU7|E9PMU7_HUMAN,tr|E9PN18|E9PN18_HUMAN,tr|A0A0J9YVR6|A0A0J9YVR6_HUMAN,tr|A0A0J9YXX5|A0A0J9YXX5_HUMAN,tr|A0A0J9YXJ8|A0A0J9YXJ8_HUMAN,tr|E9PQ56|E9PQ56_HUMAN,tr|A0A0J9YVP6|A0A0J9YVP6_HUMAN" 11 2381.2566 1.48 71876 21427 3 2381.248259 794.7595 Poly(U)-binding-splicing factor PUF60 OS=Homo sapiens OX=9606 GN=PUF60 PE=1 SV=1 4.68 3491.1 - 774460 - - - -3.5074 - 2.859 0.468 - 81.2 1 2 0 -0.0084 22 0 0 0 3.94E+07 2.65E+07 - - - 6.2459 1 221125_WJC_METTL3_EV_vs_WT_F05.21432.21432.3 3.59E-06 18/68 K.HYFQNTQGLIFVVDSNDR.E "sp|P18085|ARF4_HUMAN,sp|P84077|ARF1_HUMAN,sp|P61204|ARF3_HUMAN,sp|P84085|ARF5_HUMAN,tr|F5H423|F5H423_HUMAN,tr|C9J1Z8|C9J1Z8_HUMAN,tr|C9JPM4|C9JPM4_HUMAN,tr|C9JAK5|C9JAK5_HUMAN,tr|F5H0C7|F5H0C7_HUMAN" 9 2152.0338 4.92 71879 21432 3 2152.032418 718.3519 ADP-ribosylation factor 4 OS=Homo sapiens OX=9606 GN=ARF4 PE=1 SV=3 5.21 3491.6 - 1.26E+06 - - - -0.6268 - 3.166 0.571 - 444.6 1 2 0 -0.0013 18 0 0 0 4.12E+07 8.36E+06 - - - 7.7755 0.9999 221125_WJC_METTL3_EV_vs_WT_F05.21433.21433.3 2.81E-09 19/76 R.NSVQHQFQDTFPGPYAVLTK[136.11].D sp|Q14774|HLX_HUMAN 1 2284.1368 1.24 71880 21433 3 2284.129259 762.3862 H2.0-like homeobox protein OS=Homo sapiens OX=9606 GN=HLX PE=1 SV=3 6.74 3491.8 - 781507 - - - -3.2936 - 3.33 0.573 - 303.6 1 2 0 -0.0075 20 0 0 0 3.71E+07 3.00E+07 - - - 7.8447 1 221125_WJC_METTL3_EV_vs_WT_F05.21434.21434.3 2.25E-13 27/84 K.VGRPSNIGQAQPIIDQLAEEAR.A "sp|Q9UHX1|PUF60_HUMAN,tr|A0A0J9YYL3|A0A0J9YYL3_HUMAN,tr|A0A0J9YWM1|A0A0J9YWM1_HUMAN,tr|H0YEM1|H0YEM1_HUMAN,tr|E9PMU7|E9PMU7_HUMAN,tr|E9PN18|E9PN18_HUMAN,tr|A0A0J9YVR6|A0A0J9YVR6_HUMAN,tr|A0A0J9YXX5|A0A0J9YXX5_HUMAN,tr|A0A0J9YXJ8|A0A0J9YXJ8_HUMAN,tr|E9PQ56|E9PQ56_HUMAN,tr|A0A0J9YVP6|A0A0J9YVP6_HUMAN" 11 2361.2401 1.48 71881 21434 3 2361.237544 788.0873 Poly(U)-binding-splicing factor PUF60 OS=Homo sapiens OX=9606 GN=PUF60 PE=1 SV=1 4.68 3491.9 - 1.03E+06 - - - -1.0702 - 5.512 0.684 - 846.8 1 2 0 -0.0025 22 0 0 0 3.94E+07 2.65E+07 - - - 10.2121 0.9999 221125_WJC_METTL3_EV_vs_WT_F05.21440.21440.3 6.46E-06 Oct-52 K.VSHLLGINVTDFTR[166.11].G sp|P35579|MYH9_HUMAN 1 1580.855 1.41 71883 21440 3 1580.854223 527.9589 Myosin-9 OS=Homo sapiens OX=9606 GN=MYH9 PE=1 SV=4 6.71 3492.8 - 119752 - - - -0.4985 - 2.188 0.45 - 156 1 2 0 -0.0008 14 0 0 0 2.52E+06 1.79E+06 - - - 5.6377 0.9933 221125_WJC_METTL3_EV_vs_WT_F05.21442.21442.4 1.79E-09 14/108 L.ILHDDEVTVTEDKINALIK.A sp|P05386|RLA1_HUMAN 1 2165.158 1.9 71885 21442 4 2165.159498 542.2968 60S acidic ribosomal protein P1 OS=Homo sapiens OX=9606 GN=RPLP1 PE=1 SV=1 4.43 3493.1 - 224448 - - - 0.7085 - 2.941 0.607 - 158.2 1 1 1 0.0015 19 0 0 0 1.51E+07 7.91E+06 - - - 4.8738 1 221125_WJC_METTL3_EV_vs_WT_F05.21447.21447.3 2.95E-08 16/68 K.HYFQNTQGLIFVVDSNDR[166.11].E "sp|P18085|ARF4_HUMAN,sp|P84077|ARF1_HUMAN,sp|P61204|ARF3_HUMAN,sp|P84085|ARF5_HUMAN,tr|F5H423|F5H423_HUMAN,tr|C9J1Z8|C9J1Z8_HUMAN,tr|C9JPM4|C9JPM4_HUMAN,tr|C9JAK5|C9JAK5_HUMAN,tr|F5H0C7|F5H0C7_HUMAN" 9 2162.042 4.77 71888 21447 3 2162.038407 721.688 ADP-ribosylation factor 4 OS=Homo sapiens OX=9606 GN=ARF4 PE=1 SV=3 5.21 3493.7 - 343469 - - - -1.679 - 3.087 0.559 - 393.4 1 2 0 -0.0036 18 0 0 0 3.99E+07 8.36E+06 - - - 7.5781 1 221125_WJC_METTL3_EV_vs_WT_F05.21456.21456.4 5.74E-12 24/156 K.FWEVISDEHGIDPTGTYHGDSDLQLER.L "sp|P04350|TBB4A_HUMAN,sp|P68371|TBB4B_HUMAN,tr|M0R2D3|M0R2D3_HUMAN,tr|M0QY85|M0QY85_HUMAN,tr|M0QZL7|M0QZL7_HUMAN,tr|M0R0X0|M0R0X0_HUMAN,tr|M0QYM7|M0QYM7_HUMAN,tr|M0R278|M0R278_HUMAN,tr|M0QY37|M0QY37_HUMAN,tr|M0QX14|M0QX14_HUMAN" 10 3115.4159 0.87 71894 21456 4 3115.418227 779.8613 Tubulin beta-4A chain OS=Homo sapiens OX=9606 GN=TUBB4A PE=1 SV=2 4.14 3494.9 - 637428 - - - 0.7395 - 3.951 0.58 - 344.6 1 2 0 0.0023 27 0 0 0 1.05E+07 1.21E+07 - - - 4.7036 1 221125_WJC_METTL3_EV_vs_WT_F05.21457.21457.4 3.11E-11 24/156 K.FWEVISDEHGIDPTGTYHGDSDLQLER[166.11].L "sp|P04350|TBB4A_HUMAN,sp|P68371|TBB4B_HUMAN,tr|M0R2D3|M0R2D3_HUMAN,tr|M0QY85|M0QY85_HUMAN,tr|M0QZL7|M0QZL7_HUMAN,tr|M0R0X0|M0R0X0_HUMAN,tr|M0QYM7|M0QYM7_HUMAN,tr|M0R278|M0R278_HUMAN,tr|M0QY37|M0QY37_HUMAN,tr|M0QX14|M0QX14_HUMAN" 10 3125.4242 1 71895 21457 4 3125.422386 782.3633 Tubulin beta-4A chain OS=Homo sapiens OX=9606 GN=TUBB4A PE=1 SV=2 4.14 3495 - 582463 - - - -0.5782 - 3.799 0.571 - 344.4 1 2 0 -0.0018 27 0 0 0 1.22E+07 1.23E+07 - - - 4.6131 1 221125_WJC_METTL3_EV_vs_WT_F05.21458.21458.3 3.09E-06 17/72 K.ASGDSAR[166.11]PVLLQVAESAYR[166.11].F sp|Q9UJS0|CMC2_HUMAN 1 2009.0445 1.5 71896 21458 3 2009.045458 670.6888 Calcium-binding mitochondrial carrier protein Aralar2 OS=Homo sapiens OX=9606 GN=SLC25A13 PE=1 SV=2 6.11 3495.1 - 184702 - - - 0.4803 - 3.121 0.571 - 329.6 1 2 0 0.001 19 0 0 0 4.62E+06 3.08E+06 - - - 7.702 1 221125_WJC_METTL3_EV_vs_WT_F05.21463.21463.3 7.52E-13 21/64 R.THFTSQQLQELEATFQR.N "sp|P78337|PITX1_HUMAN,sp|Q99697|PITX2_HUMAN,sp|O75364|PITX3_HUMAN,tr|D6R9U1|D6R9U1_HUMAN,tr|D6R955|D6R955_HUMAN,tr|D6RFI4|D6RFI4_HUMAN,tr|U3KQ81|U3KQ81_HUMAN,tr|D6RBG8|D6RBG8_HUMAN" 8 2063.0072 3.78 71899 21463 3 2063.0105 688.6763 Pituitary homeobox 1 OS=Homo sapiens OX=9606 GN=PITX1 PE=1 SV=2 5.37 3495.8 - 528841 - - - 1.5909 - 4.352 0.635 - 892.1 1 2 0 0.0033 17 0 0 0 1.84E+07 4.87E+06 - - - 9.334 0.9975 221125_WJC_METTL3_EV_vs_WT_F05.21465.21465.4 0.000471 13/132 R.GLTLAPGLSPARPLFGSDFEKEK.Q sp|Q8IU81|I2BP1_HUMAN 1 2429.2955 1.13 71901 21465 4 2429.296717 608.3311 Interferon regulatory factor 2-binding protein 1 OS=Homo sapiens OX=9606 GN=IRF2BP1 PE=1 SV=1 6.18 3496.1 - 318331 - - - 0.517 - 2.497 0.314 - 108 1 2 1 0.0013 23 0 0 0 4.91E+06 4.35E+06 - - - 2.2552 0.9999 221125_WJC_METTL3_EV_vs_WT_F05.21466.21466.3 8.52E-08 Nov-96 R.TK[136.11]VENGEGTIPVESSDIVPTWDGIR[166.11].L "sp|P55265|DSRAD_HUMAN,tr|A0A3B3IRQ9|A0A3B3IRQ9_HUMAN,tr|A0A7P0Z4F9|A0A7P0Z4F9_HUMAN" 3 2716.3675 0.73 71902 21466 3 2716.365395 906.4631 Double-stranded RNA-specific adenosine deaminase OS=Homo sapiens OX=9606 GN=ADAR PE=1 SV=4 4.18 3496.2 - 263537 - - - -0.7602 - 2.469 0.643 - 66.8 1 2 1 -0.0021 25 0 0 0 4.73E+06 6.50E+06 - - - 7.7876 0.9999 221125_WJC_METTL3_EV_vs_WT_F05.21467.21467.4 4.24E-06 13/96 K.AAIDWFDGKEFHGNIIK.V "sp|Q92804|RBP56_HUMAN,tr|A0A075B7D9|A0A075B7D9_HUMAN" 2 1959.9843 1.21 71903 21467 4 1959.983165 491.0034 TATA-binding protein-associated factor 2N OS=Homo sapiens OX=9606 GN=TAF15 PE=1 SV=1 5.38 3496.3 - 227613 - - - -0.5776 - 2.546 0.507 - 127.1 1 2 1 -0.0011 17 0 0 0 4.91E+06 4.06E+06 - - - 3.9631 0.9995 221125_WJC_METTL3_EV_vs_WT_F05.21468.21468.2 0.00275 18-Sep R.NMQDLVEDLK.N "sp|P48668|K2C6C_HUMAN,sp|P04259|K2C6B_HUMAN" 2 1203.5805 68.8 71904 21468 2 1203.582557 602.7975 "Keratin, type II cytoskeletal 6C OS=Homo sapiens OX=9606 GN=KRT6C PE=1 SV=3" 4.03 3496.5 - 215472 - - - 1.6767 - 1.935 0.382 - 278.2 1 2 0 0.002 10 0 0 0 3.38E+06 4.92E+04 - - - 3.7044 0.9993 221125_WJC_METTL3_EV_vs_WT_F05.21471.21471.4 8.45E-06 Nov-96 K.AAIDWFDGK[136.11]EFHGNIIK[136.11].V "sp|Q92804|RBP56_HUMAN,tr|A0A075B7D9|A0A075B7D9_HUMAN" 2 1976.0127 1.21 71905 21471 4 1976.01492 495.0105 TATA-binding protein-associated factor 2N OS=Homo sapiens OX=9606 GN=TAF15 PE=1 SV=1 5.38 3496.9 - 372406 - - - 1.125 - 2.368 0.386 - 81.6 1 2 1 0.0022 17 0 0 0 4.91E+06 4.06E+06 - - - 2.8844 1 221125_WJC_METTL3_EV_vs_WT_F05.21473.21473.3 8.64E-06 14/92 R.YGEDGLAGESVEFQNLATLKPSNK.A "sp|P24928|RPB1_HUMAN,tr|A0A6Q8PGB0|A0A6Q8PGB0_HUMAN" 2 2566.2551 1.39 71907 21473 3 2566.258015 856.4256 DNA-directed RNA polymerase II subunit RPB1 OS=Homo sapiens OX=9606 GN=POLR2A PE=1 SV=2 4.41 3497.1 - 302449 - - - 1.1312 - 3.323 0.64 - 145.1 1 2 0 0.0029 24 0 0 0 7.25E+06 5.20E+06 - - - 8.4637 0.9999 221125_WJC_METTL3_EV_vs_WT_F05.21476.21476.4 9.78E-08 15/126 K.KVWYEWAVTAPVC[160.03]SAIHNPTGR.S "sp|O14744|ANM5_HUMAN,tr|H7BZ44|H7BZ44_HUMAN" 2 2541.2587 2.99 71910 21476 4 2541.268579 636.322 Protein arginine N-methyltransferase 5 OS=Homo sapiens OX=9606 GN=PRMT5 PE=1 SV=4 8.21 3497.5 - 214728 - - - 3.8878 - 3.143 0.542 - 145.4 1 2 0 0.0099 22 0 0 0 2.25E+06 7.52E+05 - - - 4.3155 0.9995 221125_WJC_METTL3_EV_vs_WT_F05.21477.21477.3 0.00015 8/108 R.QPSWDPSPVSSTVPAPSPLSAAAVSPSK.L "sp|Q9NQC3|RTN4_HUMAN,tr|F8W914|F8W914_HUMAN" 2 2746.3814 1.11 71911 21477 3 2746.393601 916.4677 Reticulon-4 OS=Homo sapiens OX=9606 GN=RTN4 PE=1 SV=2 5.84 3497.7 - 166516 - - - 4.4513 - 2.067 0.515 - 37.5 1 2 0 0.0122 28 0 0 0 2.58E+06 2.32E+06 - - - 5.9488 0.9999 221125_WJC_METTL3_EV_vs_WT_F05.21482.21482.4 0.000254 13/114 R.TLYVHWTDAGQLTPALLHSR.C "sp|Q8IY67|RAVR1_HUMAN,tr|E9PAU2|E9PAU2_HUMAN,tr|A0A087WZ13|A0A087WZ13_HUMAN" 3 2278.1859 0.64 71914 21482 4 2278.190265 570.5537 Ribonucleoprotein PTB-binding 1 OS=Homo sapiens OX=9606 GN=RAVER1 PE=1 SV=1 6.61 3498.3 - 167538 - - - 1.9375 - 2.659 0.428 - 95.3 1 2 0 0.0044 20 0 0 0 2.98E+06 4.65E+06 - - - 3.277 0.9973 221125_WJC_METTL3_EV_vs_WT_F05.21483.21483.3 0.00141 Sep-64 K.AAIDWFDGKEFHGNIIK.V "sp|Q92804|RBP56_HUMAN,tr|A0A075B7D9|A0A075B7D9_HUMAN" 2 1959.9843 1.41 71915 21483 3 1959.988675 654.3354 TATA-binding protein-associated factor 2N OS=Homo sapiens OX=9606 GN=TAF15 PE=1 SV=1 5.38 3498.5 - 176286 - - - 2.2337 - 1.833 0.384 - 75.1 1 2 1 0.0044 17 0 0 0 2.16E+06 1.53E+06 - - - 4.3508 0.9993 221125_WJC_METTL3_EV_vs_WT_F05.21484.21484.4 5.77E-06 13/114 R.TLYVHWTDAGQLTPALLHSR[166.11].C "sp|Q8IY67|RAVR1_HUMAN,tr|E9PAU2|E9PAU2_HUMAN,tr|A0A087WZ13|A0A087WZ13_HUMAN" 3 2288.1941 0.64 71916 21484 4 2288.202088 573.0558 Ribonucleoprotein PTB-binding 1 OS=Homo sapiens OX=9606 GN=RAVER1 PE=1 SV=1 6.61 3498.6 - 282551 - - - 3.4818 - 2.052 0.399 - 84.3 1 2 0 0.008 20 0 0 0 2.98E+06 4.65E+06 - - - 2.937 0.9995 221125_WJC_METTL3_EV_vs_WT_F05.21487.21487.4 0.00232 Aug-78 R.SLLSQMLHYDPNKR.L "sp|P24941|CDK2_HUMAN,tr|G3V5T9|G3V5T9_HUMAN,tr|E7ESI2|E7ESI2_HUMAN" 3 1700.8668 0.78 71919 21487 4 1700.86983 426.224 Cyclin-dependent kinase 2 OS=Homo sapiens OX=9606 GN=CDK2 PE=1 SV=2 8.33 3499 - 93020.8 - - - 1.7667 - 1.444 0.362 - 34 1 2 0 0.003 14 0 0 0 1.37E+06 1.75E+06 - - - 2.5097 0.9826 221125_WJC_METTL3_EV_vs_WT_F05.21488.21488.4 0.259 Jun-96 K.SFPLHFDENSFFAGDK[136.11]K[136.11].E "sp|Q96HE7|ERO1A_HUMAN,tr|G3V2H0|G3V2H0_HUMAN" 2 2000.9603 0.52 71920 21488 4 2000.969319 501.2474 ERO1-like protein alpha OS=Homo sapiens OX=9606 GN=ERO1A PE=1 SV=2 5.36 3499.1 - 89986.2 - - - 4.4938 - 0.974 0.296 - 16.9 1 2 0 0.009 17 0 0 0 7.19E+05 1.38E+06 - - - 1.7907 0.9999 221125_WJC_METTL3_EV_vs_WT_F05.21489.21489.3 9.98E-05 Aug-64 R.DAPTHLPSVDLSNPFTK[136.11].E sp|Q5VT52|RPRD2_HUMAN 1 1845.9352 1.48 71921 21489 3 1845.934387 616.319 Regulation of nuclear pre-mRNA domain-containing protein 2 OS=Homo sapiens OX=9606 GN=RPRD2 PE=1 SV=1 5.21 3499.2 - 84788.2 - - - -0.4556 - 1.9 0.469 - 47.9 1 2 0 -0.0008 17 0 0 0 2.29E+06 1.55E+06 - - - 5.3902 0.9969 221125_WJC_METTL3_EV_vs_WT_F05.21490.21490.3 0.000717 Sep-52 R.SLLSQMLHYDPNKR.L "sp|P24941|CDK2_HUMAN,tr|G3V5T9|G3V5T9_HUMAN,tr|E7ESI2|E7ESI2_HUMAN" 3 1700.8668 0.95 71922 21490 3 1700.874504 567.9629 Cyclin-dependent kinase 2 OS=Homo sapiens OX=9606 GN=CDK2 PE=1 SV=2 8.33 3499.4 - 71414.4 - - - 4.5148 - 1.712 0.392 - 90.3 1 2 0 0.0077 14 0 0 0 8.58E+05 9.02E+05 - - - 4.3371 1 221125_WJC_METTL3_EV_vs_WT_F05.21494.21494.3 4.48E-12 22/80 R.VIISAPSADAPMFVMGVNHEK.Y "sp|P04406|G3P_HUMAN,tr|E7EUT5|E7EUT5_HUMAN" 2 2212.102 1.21 71924 21494 3 2212.10597 738.3746 Glyceraldehyde-3-phosphate dehydrogenase OS=Homo sapiens OX=9606 GN=GAPDH PE=1 SV=3 5.32 3499.8 - 941671 - - - 1.7739 - 3.805 0.668 - 477.7 1 2 0 0.0039 21 0 0 0 1.19E+07 9.83E+06 - - - 9.1902 0.9999 221125_WJC_METTL3_EV_vs_WT_F05.21495.21495.4 1.00E-09 21/114 R.IEEVPELPLVVEDKVEGYKK.T "sp|P36578|RL4_HUMAN,tr|H3BM89|H3BM89_HUMAN" 2 2312.2515 0.69 71925 21495 4 2312.257376 579.0702 60S ribosomal protein L4 OS=Homo sapiens OX=9606 GN=RPL4 PE=1 SV=5 4.42 3500 - 407975 - - - 2.5283 - 3.717 0.591 - 432.8 1 2 1 0.0058 20 0 0 0 8.01E+06 1.16E+07 - - - 4.8074 0.9999 221125_WJC_METTL3_EV_vs_WT_F05.21496.21496.3 2.17E-09 15/96 R.TKVENGEGTIPVESSDIVPTWDGIR.L "sp|P55265|DSRAD_HUMAN,tr|A0A3B3IRQ9|A0A3B3IRQ9_HUMAN,tr|A0A7P0Z4F9|A0A7P0Z4F9_HUMAN" 3 2698.345 0.73 71926 21496 3 2698.350133 900.4556 Double-stranded RNA-specific adenosine deaminase OS=Homo sapiens OX=9606 GN=ADAR PE=1 SV=4 4.18 3500.1 - 487656 - - - 1.906 - 2.895 0.611 - 129.9 1 2 1 0.0051 25 0 0 0 4.73E+06 6.50E+06 - - - 7.7962 0.9756 221125_WJC_METTL3_EV_vs_WT_F05.21499.21499.3 0.0294 Sep-64 R.DAPTHLPSVDLSNPFTK.E sp|Q5VT52|RPRD2_HUMAN 1 1837.921 1.48 71929 21499 3 1837.927315 613.6476 Regulation of nuclear pre-mRNA domain-containing protein 2 OS=Homo sapiens OX=9606 GN=RPRD2 PE=1 SV=1 5.21 3500.5 - 199745 - - - 3.4207 - 1.556 0.234 - 54.5 1 2 0 0.0063 17 0 0 0 2.29E+06 1.55E+06 - - - 2.2641 0.9959 221125_WJC_METTL3_EV_vs_WT_F05.21500.21500.2 0.0091 Aug-36 K.TSSAETPTIPLGSAVEAIK.A "sp|Q16891|MIC60_HUMAN,tr|B9A067|B9A067_HUMAN,tr|C9J406|C9J406_HUMAN,tr|H7C463|H7C463_HUMAN" 4 1870.9888 1.6 71930 21500 2 1870.995954 936.5017 MICOS complex subunit MIC60 OS=Homo sapiens OX=9606 GN=IMMT PE=1 SV=1 4.53 3500.6 - 163584 - - - 3.8375 - 1.453 0.418 - 87.8 1 2 0 0.0072 19 0 0 0 6.52E+06 4.06E+06 - - - 3.0447 1 221125_WJC_METTL3_EV_vs_WT_F05.21501.21501.3 1.32E-09 17/104 R.RPPPAPAQPPEPEALPTIYVVTPTYAR.L "sp|O94766|B3GA3_HUMAN,tr|G3V150|G3V150_HUMAN,tr|E9PNA1|E9PNA1_HUMAN" 3 2927.5545 0.69 71931 21501 3 2927.559501 976.8588 Galactosylgalactosylxylosylprotein 3-beta-glucuronosyltransferase 3 OS=Homo sapiens OX=9606 GN=B3GAT3 PE=1 SV=2 6.14 3500.7 - 143348 - - - 1.6983 - 3.316 0.639 - 234.2 1 2 0 0.005 27 0 0 0 1.35E+07 1.96E+07 - - - 8.4208 0.9883 221125_WJC_METTL3_EV_vs_WT_F05.21505.21505.3 6.35E-07 14/56 N.QLDGIHLLDPDVVAR[166.11].F sp|Q86U44|MTA70_HUMAN 1 1669.9027 0.82 71933 21505 3 1669.907487 557.6415 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 4.41 3501.3 - 547915 - - - 2.8726 - 2.69 0.476 - 285.8 1 1 0 0.0048 15 0 0 0 7.12E+06 8.72E+06 - - - 6.4277 1 221125_WJC_METTL3_EV_vs_WT_F05.21507.21507.4 2.68E-08 19/156 K.FWEVISDEHGIDPTGTYHGDSDLQLDR.L "sp|P07437|TBB5_HUMAN,tr|Q5JP53|Q5JP53_HUMAN" 2 3101.4003 0.52 71935 21507 4 3101.409578 776.3573 Tubulin beta chain OS=Homo sapiens OX=9606 GN=TUBB PE=1 SV=2 4.08 3501.6 - 532934 - - - 3.0003 - 3.342 0.595 - 190 1 2 0 0.0093 27 0 0 0 9.01E+06 1.73E+07 - - - 4.7798 0.9789 221125_WJC_METTL3_EV_vs_WT_F05.21508.21508.3 3.79E-09 Dec-68 T.ISANGDKEIGNIISDAMK.K "sp|P10809|CH60_HUMAN,tr|A0A7I2V599|A0A7I2V599_HUMAN,tr|E7EXB4|E7EXB4_HUMAN,tr|A0A7I2YQ71|A0A7I2YQ71_HUMAN,tr|E7ESH4|E7ESH4_HUMAN,tr|A0A7I2V5M1|A0A7I2V5M1_HUMAN,tr|A0A7I2V5K3|A0A7I2V5K3_HUMAN,tr|A0A7I2V369|A0A7I2V369_HUMAN" 8 1874.9408 1.3 71936 21508 3 1874.945615 625.9875 "60 kDa heat shock protein, mitochondrial OS=Homo sapiens OX=9606 GN=HSPD1 PE=1 SV=2" 4.56 3501.7 - 313471 - - - 2.5798 - 2.753 0.573 - 178.2 1 1 1 0.0048 18 0 0 0 3.44E+06 2.65E+06 - - - 7.4487 1 221125_WJC_METTL3_EV_vs_WT_F05.21509.21509.4 4.24E-12 15/132 K.IVGAPMHDLLLWNNATVTTC[160.03]HSK.T "sp|P11586|C1TC_HUMAN,tr|F5H2F4|F5H2F4_HUMAN,tr|V9GZ78|V9GZ78_HUMAN,tr|V9GYY3|V9GYY3_HUMAN" 4 2577.2832 1.84 71937 21509 4 2577.292351 645.3281 "C-1-tetrahydrofolate synthase, cytoplasmic OS=Homo sapiens OX=9606 GN=MTHFD1 PE=1 SV=4" 6.91 3501.9 - 292924 - - - 3.551 - 2.872 0.685 - 119.4 1 2 0 0.0092 23 0 0 0 6.00E+06 3.26E+06 - - - 5.5275 1 221125_WJC_METTL3_EV_vs_WT_F05.21512.21512.2 1.70E-07 20-Oct K.GFAFVQYVNER.N "sp|P07910|HNRPC_HUMAN,tr|G3V251|G3V251_HUMAN,tr|B4DY08|B4DY08_HUMAN,tr|G3V575|G3V575_HUMAN,tr|B4DSU6|B4DSU6_HUMAN,tr|G3V3K6|G3V3K6_HUMAN,tr|B2R5W2|B2R5W2_HUMAN,tr|G3V4C1|G3V4C1_HUMAN,tr|G3V576|G3V576_HUMAN,tr|G3V5X6|G3V5X6_HUMAN,tr|G3V4W0|G3V4W0_HUMAN,tr|G3V555|G3V555_HUMAN,tr|G3V4M8|G3V4M8_HUMAN,tr|G3V2Q1|G3V2Q1_HUMAN" 14 1328.6513 0.73 71940 21512 2 1328.656423 665.3329 Heterogeneous nuclear ribonucleoproteins C1\C2 OS=Homo sapiens OX=9606 GN=HNRNPC PE=1 SV=4 6 3502.2 - 168073 - - - 3.8287 - 2.305 0.599 - 435 1 2 0 0.0051 11 0 0 0 1.58E+06 2.17E+06 - - - 5.7227 1 221125_WJC_METTL3_EV_vs_WT_F05.21514.21514.3 1.12E-08 13/104 R.R[166.11]PPPAPAQPPEPEALPTIYVVTPTYAR[166.11].L "sp|O94766|B3GA3_HUMAN,tr|G3V150|G3V150_HUMAN,tr|E9PNA1|E9PNA1_HUMAN" 3 2947.5711 0.69 71942 21514 3 2947.577935 983.531 Galactosylgalactosylxylosylprotein 3-beta-glucuronosyltransferase 3 OS=Homo sapiens OX=9606 GN=B3GAT3 PE=1 SV=2 6.14 3502.5 - 135629 - - - 2.3294 - 3.049 0.611 - 107 1 2 0 0.0069 27 0 0 0 1.35E+07 1.96E+07 - - - 7.9149 0.9999 221125_WJC_METTL3_EV_vs_WT_F05.21521.21521.3 7.83E-09 14/96 K.STVDGLQVTQLNVDHTTENEDELFR.L sp|Q15750|TAB1_HUMAN 1 2859.3523 2.6 71947 21521 3 2859.361156 954.1247 TGF-beta-activated kinase 1 and MAP3K7-binding protein 1 OS=Homo sapiens OX=9606 GN=TAB1 PE=1 SV=1 4.01 3503.4 - 264651 - - - 3.1112 - 3.062 0.597 - 134 1 2 0 0.0089 25 0 0 0 2.07E+06 7.96E+05 - - - 7.7681 0.9997 221125_WJC_METTL3_EV_vs_WT_F05.21522.21522.2 3.04E-06 Nov-36 K.TSSAETPTIPLGSAVEAIK[136.11].A "sp|Q16891|MIC60_HUMAN,tr|B9A067|B9A067_HUMAN,tr|C9J406|C9J406_HUMAN,tr|H7C463|H7C463_HUMAN" 4 1879.003 1.6 71948 21522 2 1879.007026 940.5088 MICOS complex subunit MIC60 OS=Homo sapiens OX=9606 GN=IMMT PE=1 SV=1 4.53 3503.6 - 187107 - - - 2.1565 - 2.05 0.538 - 187.3 1 2 0 0.0041 19 0 0 0 6.52E+06 4.06E+06 - - - 4.7782 0.9994 221125_WJC_METTL3_EV_vs_WT_F05.21526.21526.4 0.0333 Sep-90 K.LK[136.11]PEGLHQLLAGFEDK[136.11].S sp|Q9BY32|ITPA_HUMAN 1 1809.996 1.25 71952 21526 4 1809.997956 453.5063 Inosine triphosphate pyrophosphatase OS=Homo sapiens OX=9606 GN=ITPA PE=1 SV=2 5.45 3504.1 - 106183 - - - 1.089 - 1.621 0.33 - 45.5 1 2 0 0.002 16 0 0 0 2.04E+06 1.63E+06 - - - 2.2679 0.9997 221125_WJC_METTL3_EV_vs_WT_F05.21529.21529.3 0.00356 Dec-60 K.LK[136.11]PEGLHQLLAGFEDK[136.11].S sp|Q9BY32|ITPA_HUMAN 1 1809.996 1.73 71955 21529 3 1810.003401 604.3393 Inosine triphosphate pyrophosphatase OS=Homo sapiens OX=9606 GN=ITPA PE=1 SV=2 5.45 3504.5 - 85094.9 - - - 4.0972 - 2.516 0.49 - 103.4 1 2 0 0.0074 16 0 0 0 2.19E+06 1.26E+06 - - - 6.3684 0.9108 221125_WJC_METTL3_EV_vs_WT_F05.21530.21530.3 3.30E-07 Dec-64 L.RSDPDLVAQNIDVVLNR.R "sp|Q9UBU9|NXF1_HUMAN,tr|B4E227|B4E227_HUMAN,tr|E9PIN3|E9PIN3_HUMAN" 3 1923.0174 0.56 71956 21530 3 1923.03011 642.0131 Nuclear RNA export factor 1 OS=Homo sapiens OX=9606 GN=NXF1 PE=1 SV=1 4.43 3504.6 - 64943.2 - - - 6.6156 - 2.376 0.571 - 197.2 1 1 0 0.0127 17 0 0 0 4.88E+05 8.73E+05 - - - 7.0889 0.9999 221125_WJC_METTL3_EV_vs_WT_F05.21534.21534.3 4.56E-07 19/72 R.VQTLEELEELGKEEC[160.03]FQNK.E sp|Q9BVJ6|UT14A_HUMAN 1 2322.1049 8.8 71958 21534 3 2322.108543 775.0423 U3 small nucleolar RNA-associated protein 14 homolog A OS=Homo sapiens OX=9606 GN=UTP14A PE=1 SV=1 4.21 3505.2 - 976605 - - - 1.5503 - 3.209 0.535 - 389 1 2 1 0.0036 19 0 0 0 1.78E+07 2.02E+06 - - - 7.3683 1 221125_WJC_METTL3_EV_vs_WT_F05.21535.21535.3 2.44E-09 21/116 R.GGGFGGGSSFGGGSGFSGGGFGGGGFGGGR.F sp|P35908|K22E_HUMAN 1 2398.0111 7645.58 71959 21535 3 2398.014595 800.3443 "Keratin, type II cytoskeletal 2 epidermal OS=Homo sapiens OX=9606 GN=KRT2 PE=1 SV=2" 9.75 3505.3 - 432507 - - - 1.4433 - 4.239 0.549 - 210.6 1 2 0 0.0035 30 0 0 0 2.17E+08 2.83E+04 - - - 7.9827 1 221125_WJC_METTL3_EV_vs_WT_F05.21536.21536.3 3.67E-07 14/60 K.LKPEGLHQLLAGFEDK.S sp|Q9BY32|ITPA_HUMAN 1 1793.9676 1.73 71960 21536 3 1793.970159 598.9965 Inosine triphosphate pyrophosphatase OS=Homo sapiens OX=9606 GN=ITPA PE=1 SV=2 5.45 3505.4 - 260096 - - - 1.4348 - 2.883 0.586 - 123 1 2 0 0.0026 16 0 0 0 2.19E+06 1.26E+06 - - - 7.7894 0.9989 221125_WJC_METTL3_EV_vs_WT_F05.21538.21538.4 0.069 Dec-90 K.LKPEGLHQLLAGFEDK.S sp|Q9BY32|ITPA_HUMAN 1 1793.9676 1.25 71962 21538 4 1793.970531 449.4992 Inosine triphosphate pyrophosphatase OS=Homo sapiens OX=9606 GN=ITPA PE=1 SV=2 5.45 3505.7 - 210799 - - - 1.6422 - 2.344 0.296 - 76.8 1 2 0 0.0029 16 0 0 0 2.04E+06 1.63E+06 - - - 2.1016 0.9823 221125_WJC_METTL3_EV_vs_WT_F05.21539.21539.3 1.52E-05 Oct-84 S.AASITPLLQTQPQPLLQQPQQK.A "sp|Q8IX12|CCAR1_HUMAN,tr|F5H2E6|F5H2E6_HUMAN,tr|F5H1H2|F5H1H2_HUMAN,tr|A0A0C4DGG8|A0A0C4DGG8_HUMAN,tr|F5H3E1|F5H3E1_HUMAN" 5 2427.3486 7.95 71963 21539 3 2427.351729 810.1235 Cell division cycle and apoptosis regulator protein 1 OS=Homo sapiens OX=9606 GN=CCAR1 PE=1 SV=2 8.8 3505.8 - 206572 - - - 1.306 - 2.227 0.403 - 72.5 1 1 0 0.0032 22 0 0 0 9.96E+06 1.25E+06 - - - 4.9304 0.9999 221125_WJC_METTL3_EV_vs_WT_F05.21542.21542.4 1.12E-05 9/126 K.VGR[166.11]PSNIGQAQPIIDQLAEEAR[166.11].A "sp|Q9UHX1|PUF60_HUMAN,tr|A0A0J9YYL3|A0A0J9YYL3_HUMAN,tr|A0A0J9YWM1|A0A0J9YWM1_HUMAN,tr|H0YEM1|H0YEM1_HUMAN,tr|E9PMU7|E9PMU7_HUMAN,tr|E9PN18|E9PN18_HUMAN,tr|A0A0J9YVR6|A0A0J9YVR6_HUMAN,tr|A0A0J9YXX5|A0A0J9YXX5_HUMAN,tr|A0A0J9YXJ8|A0A0J9YXJ8_HUMAN,tr|E9PQ56|E9PQ56_HUMAN,tr|A0A0J9YVP6|A0A0J9YVP6_HUMAN" 11 2381.2566 1.89 71966 21542 4 2381.261919 596.3214 Poly(U)-binding-splicing factor PUF60 OS=Homo sapiens OX=9606 GN=PUF60 PE=1 SV=1 4.68 3506.2 - 100196 - - - 2.2291 - 2.031 0.48 - 53.4 1 2 0 0.0053 22 0 0 0 1.84E+06 9.71E+05 - - - 3.6343 0.9756 221125_WJC_METTL3_EV_vs_WT_F05.21548.21548.3 1.85E-09 23/72 K.NMDPLNDNVATLLHQSSDR.F sp|P35580|MYH10_HUMAN 1 2139.0015 0.21 71970 21548 3 2139.988507 714.0078 Myosin-10 OS=Homo sapiens OX=9606 GN=MYH10 PE=1 SV=3 4.41 3507.1 - 674520 - - - 461.4429 - 3.749 0.62 - 468.9 1 2 0 0.987 19 0 0 0 4.08E+06 1.90E+07 - - - 8.4256 1 221125_WJC_METTL3_EV_vs_WT_F05.21549.21549.4 3.73E-09 24/156 K.FWEVISDEHGIDPTGTYHGDSDLQLDR[166.11].L "sp|P07437|TBB5_HUMAN,tr|Q5JP53|Q5JP53_HUMAN" 2 3111.4085 0.62 71971 21549 4 3111.41061 778.8594 Tubulin beta chain OS=Homo sapiens OX=9606 GN=TUBB PE=1 SV=2 4.08 3507.2 - 891439 - - - 0.6643 - 3.719 0.596 - 312.1 1 2 0 0.0021 27 0 0 0 1.27E+07 2.04E+07 - - - 4.824 1 221125_WJC_METTL3_EV_vs_WT_F05.21550.21550.4 3.54E-07 11/132 K.IVGAPMHDLLLWNNATVTTC[160.03]HSK[136.11].T "sp|P11586|C1TC_HUMAN,tr|F5H2F4|F5H2F4_HUMAN,tr|V9GZ78|V9GZ78_HUMAN,tr|V9GYY3|V9GYY3_HUMAN" 4 2585.2974 2.1 71972 21550 4 2585.298287 647.3316 "C-1-tetrahydrofolate synthase, cytoplasmic OS=Homo sapiens OX=9606 GN=MTHFD1 PE=1 SV=4" 6.91 3507.3 - 371397 - - - 0.3435 - 2.282 0.575 - 60.6 1 2 0 0.0009 23 0 0 0 6.00E+06 2.86E+06 - - - 4.4979 0.9874 221125_WJC_METTL3_EV_vs_WT_F05.21552.21552.3 0.0767 Aug-72 K.TSSAETPTIPLGSAVEAIK.A "sp|Q16891|MIC60_HUMAN,tr|B9A067|B9A067_HUMAN,tr|C9J406|C9J406_HUMAN,tr|H7C463|H7C463_HUMAN" 4 1870.9888 1.8 71974 21552 3 1870.994196 624.6702 MICOS complex subunit MIC60 OS=Homo sapiens OX=9606 GN=IMMT PE=1 SV=1 4.53 3507.6 - 218381 - - - 2.8979 - 1.437 0.271 - 34.3 1 2 0 0.0054 19 0 0 0 2.57E+06 1.43E+06 - - - 2.4506 1 221125_WJC_METTL3_EV_vs_WT_F05.21553.21553.2 3.52E-14 24/58 R.GGGFGGGSSFGGGSGFSGGGFGGGGFGGGR.F sp|P35908|K22E_HUMAN 1 2398.0111 999 71975 21553 2 2398.016229 1200.0128 "Keratin, type II cytoskeletal 2 epidermal OS=Homo sapiens OX=9606 GN=KRT2 PE=1 SV=2" 9.75 3507.7 - 187311 - - - 2.1247 - 4.956 0.705 - 1244 1 2 0 0.0051 30 0 0 0 2.35E+07 0.00E+00 - - - 8.1817 1 221125_WJC_METTL3_EV_vs_WT_F05.21563.21563.3 8.06E-08 19/96 K.IDSIPHLNNSTPLVDPSVYGYGVQK.R sp|Q96I24|FUBP3_HUMAN 1 2712.3759 2.07 71983 21563 3 2712.377519 905.1326 Far upstream element-binding protein 3 OS=Homo sapiens OX=9606 GN=FUBP3 PE=1 SV=2 5.21 3509 - 474957 - - - 0.5984 - 3.715 0.624 - 224.6 1 2 0 0.0016 25 0 0 0 1.70E+08 8.21E+07 - - - 8.5158 0.9999 221125_WJC_METTL3_EV_vs_WT_F05.21566.21566.3 2.03E-07 Sep-64 K.DLKPVLDSYVFNDGSSR.E "sp|Q99816|TS101_HUMAN,tr|F5H442|F5H442_HUMAN" 2 1910.9374 1.57 71986 21566 3 1910.940244 637.9864 Tumor susceptibility gene 101 protein OS=Homo sapiens OX=9606 GN=TSG101 PE=1 SV=2 4.43 3509.4 - 164418 - - - 1.4846 - 1.95 0.544 - 70.6 1 2 0 0.0028 17 0 0 0 1.90E+06 1.21E+06 - - - 6.2914 0.9994 221125_WJC_METTL3_EV_vs_WT_F05.21568.21568.4 0.00773 8/102 K.LAFPSPFGHLSEGFSHSR.W "sp|Q13501|SQSTM_HUMAN,tr|E9PFW8|E9PFW8_HUMAN,tr|E7EMC7|E7EMC7_HUMAN,tr|C9JRJ8|C9JRJ8_HUMAN" 4 1971.9591 2.8 71988 21568 4 1971.960109 493.9971 Sequestosome-1 OS=Homo sapiens OX=9606 GN=SQSTM1 PE=1 SV=1 6.92 3509.7 - 92154.7 - - - 0.4889 - 1.748 0.327 - 30.6 1 2 0 0.001 18 0 0 0 2.64E+06 9.43E+05 - - - 2.2632 0.9971 221125_WJC_METTL3_EV_vs_WT_F05.21569.21569.4 0.144 5/108 K.KISSIQSIVPALEIANAHR.K "sp|P10809|CH60_HUMAN,tr|A0A7I2V2X6|A0A7I2V2X6_HUMAN,tr|A0A7I2YQK6|A0A7I2YQK6_HUMAN,tr|A0A7I2V599|A0A7I2V599_HUMAN,tr|A0A7I2YQ71|A0A7I2YQ71_HUMAN,tr|A0A7I2V5M1|A0A7I2V5M1_HUMAN,tr|A0A7I2V5K3|A0A7I2V5K3_HUMAN,tr|A0A7I2V369|A0A7I2V369_HUMAN" 8 2046.1586 1.81 71989 21569 4 2046.159769 512.5469 "60 kDa heat shock protein, mitochondrial OS=Homo sapiens OX=9606 GN=HSPD1 PE=1 SV=2" 8.75 3509.8 - 83521.5 - - - 0.5845 - 1.381 0.289 - 12.2 2 2 0 0.0012 19 0 0 0 5.55E+05 3.07E+05 - - - 1.6209 1 221125_WJC_METTL3_EV_vs_WT_F05.21576.21576.3 8.07E-09 22/96 K.IDSIPHLNNSTPLVDPSVYGYGVQK[136.11].R sp|Q96I24|FUBP3_HUMAN 1 2720.3901 2.07 71994 21576 3 2720.3928 907.804 Far upstream element-binding protein 3 OS=Homo sapiens OX=9606 GN=FUBP3 PE=1 SV=2 5.21 3510.7 - 649654 - - - 0.994 - 3.643 0.658 - 416.8 1 2 0 0.0027 25 0 0 0 1.70E+08 8.21E+07 - - - 8.8496 0.9986 221125_WJC_METTL3_EV_vs_WT_F05.21577.21577.2 0.00182 14-Jun K.DVIEEYFK[136.11].C sp|P25398|RS12_HUMAN 1 1049.5161 2.23 71995 21577 2 1049.516284 525.7653 40S ribosomal protein S12 OS=Homo sapiens OX=9606 GN=RPS12 PE=1 SV=3 4.14 3510.8 - 98944.4 - - - 0.1963 - 1.235 0.324 - 84.9 1 2 0 0.0002 8 0 0 0 3.30E+06 1.48E+06 - - - 2.0706 0.9938 221125_WJC_METTL3_EV_vs_WT_F05.21584.21584.3 0.0847 Oct-68 R.GLDK[136.11]LEENLPILQQPTEK[136.11].V "sp|O60664|PLIN3_HUMAN,tr|K7EL96|K7EL96_HUMAN,tr|K7ER39|K7ER39_HUMAN" 3 2080.1387 2.02 72000 21584 3 2080.134694 694.3868 Perilipin-3 OS=Homo sapiens OX=9606 GN=PLIN3 PE=1 SV=3 4.41 3511.8 - 291811 - - - -1.9191 - 2.015 0.286 - 114.9 1 2 1 -0.004 18 0 0 0 8.17E+06 4.04E+06 - - - 3.4721 0.9997 221125_WJC_METTL3_EV_vs_WT_F05.21598.21598.4 2.86E-06 20/132 R.IQEIIEQLDVTTSEYEKEKLNER.L "sp|P10809|CH60_HUMAN,tr|A0A7I2V2X6|A0A7I2V2X6_HUMAN,tr|A0A7I2YQK6|A0A7I2YQK6_HUMAN,tr|A0A7I2V599|A0A7I2V599_HUMAN" 4 2806.4236 1.1 72010 21598 4 2806.428907 702.6132 "60 kDa heat shock protein, mitochondrial OS=Homo sapiens OX=9606 GN=HSPD1 PE=1 SV=2" 4.31 3513.6 - 427240 - - - 1.8789 - 3.957 0.454 - 358.7 1 2 2 0.0053 23 0 0 0 3.02E+06 2.75E+06 - - - 3.6218 0.9809 221125_WJC_METTL3_EV_vs_WT_F05.21599.21599.4 1.41E-07 20/114 R.PLFPHVLC[160.03]HNC[160.03]AVEFNFGQK[136.11].E "sp|Q00839|HNRPU_HUMAN,tr|A0A1W2PQL0|A0A1W2PQL0_HUMAN,tr|A0A1W2PPL4|A0A1W2PPL4_HUMAN,tr|A0A1W2PQ74|A0A1W2PQ74_HUMAN,tr|Q5RI18|Q5RI18_HUMAN,tr|A0A1W2PP35|A0A1W2PP35_HUMAN,tr|A0A1W2PPS1|A0A1W2PPS1_HUMAN,tr|A0A1W2PRZ7|A0A1W2PRZ7_HUMAN,tr|A0A1W2PPH7|A0A1W2PPH7_HUMAN,tr|A0A1W2PP34|A0A1W2PP34_HUMAN,tr|A0A1X7SBS1|A0A1X7SBS1_HUMAN" 11 2421.1602 1.32 72011 21599 4 2421.152244 606.2973 Heterogeneous nuclear ribonucleoprotein U OS=Homo sapiens OX=9606 GN=HNRNPU PE=1 SV=6 7.24 3513.7 - 360917 - - - -3.2765 - 3.155 0.475 - 338.6 1 1 0 -0.0079 20 0 0 0 3.24E+07 2.46E+07 - - - 3.7423 0.9997 221125_WJC_METTL3_EV_vs_WT_F05.21600.21600.2 0.0576 14-Jul K.DVIEEYFK.C sp|P25398|RS12_HUMAN 1 1041.5019 2.23 72012 21600 2 1041.501138 521.7582 40S ribosomal protein S12 OS=Homo sapiens OX=9606 GN=RPS12 PE=1 SV=3 4.14 3513.9 - 263693 - - - -0.7105 - 1.673 0.402 - 170.7 1 2 0 -0.0007 8 0 0 0 3.30E+06 1.48E+06 - - - 3.562 0.9995 221125_WJC_METTL3_EV_vs_WT_F05.21607.21607.4 0.066 11/180 K.VK[136.11]PTLIAVR[166.11]PPVPLPAPSHPASTNEPIVLED.- sp|O94776|MTA2_HUMAN 1 3271.8299 1.97 72017 21607 4 3271.824423 818.9648 Metastasis-associated protein MTA2 OS=Homo sapiens OX=9606 GN=MTA2 PE=1 SV=1 5.54 3514.8 - 445604 - - - -1.6801 - 1.787 0.352 - 32.4 1 2 0 -0.0055 31 0 0 0 1.30E+07 6.59E+06 - - - 2.4647 0.9999 221125_WJC_METTL3_EV_vs_WT_F05.21613.21613.4 2.45E-06 13/84 R.GIEKPPFELPDFIKR.T "sp|Q13435|SF3B2_HUMAN,tr|E9PPJ0|E9PPJ0_HUMAN" 2 1784.9825 1.21 72023 21613 4 1784.982832 447.2529 Splicing factor 3B subunit 2 OS=Homo sapiens OX=9606 GN=SF3B2 PE=1 SV=2 6.18 3515.5 - 188226 - - - 0.1826 - 2.489 0.466 - 107 1 2 0 0.0003 15 0 0 0 5.65E+06 4.67E+06 - - - 3.6083 1 221125_WJC_METTL3_EV_vs_WT_F05.21622.21622.3 6.92E-11 14/92 R.KEEENASVIDSAELQAYPALVVEK.M sp|P78527|PRKDC_HUMAN 1 2631.3279 1.16 72030 21622 3 2631.319817 878.1166 DNA-dependent protein kinase catalytic subunit OS=Homo sapiens OX=9606 GN=PRKDC PE=1 SV=3 4.14 3516.6 - 417844 - - - -3.0882 - 3.152 0.663 - 159 1 2 0 -0.0081 24 0 0 0 5.68E+06 4.91E+06 - - - 8.596 1 221125_WJC_METTL3_EV_vs_WT_F05.21628.21628.3 9.48E-09 14/92 R.K[136.11]EEENASVIDSAELQAYPALVVEK[136.11].M sp|P78527|PRKDC_HUMAN 1 2647.3563 1.16 72034 21628 3 2647.348803 883.4594 DNA-dependent protein kinase catalytic subunit OS=Homo sapiens OX=9606 GN=PRKDC PE=1 SV=3 4.14 3517.4 - 376270 - - - -2.8481 - 3.279 0.629 - 136.6 1 2 0 -0.0075 24 0 0 0 5.68E+06 4.91E+06 - - - 8.3088 1 221125_WJC_METTL3_EV_vs_WT_F05.21636.21636.4 7.55E-07 16/144 K.IDSIPHLNNSTPLVDPSVYGYGVQK.R sp|Q96I24|FUBP3_HUMAN 1 2712.3759 1.8 72040 21636 4 2712.372985 679.1013 Far upstream element-binding protein 3 OS=Homo sapiens OX=9606 GN=FUBP3 PE=1 SV=2 5.21 3518.4 - 1.03E+06 - - - -1.0732 - 3.069 0.523 - 110.5 1 2 0 -0.0029 25 0 0 0 7.22E+06 4.00E+06 - - - 4.1341 1 221125_WJC_METTL3_EV_vs_WT_F05.21646.21646.3 1.05E-08 20/108 R.AAESLTAIPEPASPQLLETPIHASQIQK.V sp|Q14676|MDC1_HUMAN 1 2939.5604 0.82 72045 21646 3 2939.561499 980.8607 Mediator of DNA damage checkpoint protein 1 OS=Homo sapiens OX=9606 GN=MDC1 PE=1 SV=3 4.75 3519.7 - 975945 - - - 0.3728 - 3.475 0.569 - 279.4 1 2 0 0.0011 28 0 0 0 1.28E+07 1.57E+07 - - - 7.7491 1 221125_WJC_METTL3_EV_vs_WT_F05.21655.21655.4 1.28E-10 17/114 K.K[136.11]LGGSLADSYLDEGFLLDK[136.11]K[136.11].L "sp|P78371|TCPB_HUMAN,tr|F8VQ14|F8VQ14_HUMAN,tr|F5GWF6|F5GWF6_HUMAN" 3 2192.1791 0.4 72051 21655 4 2192.174866 549.0521 T-complex protein 1 subunit beta OS=Homo sapiens OX=9606 GN=CCT2 PE=1 SV=4 4.68 3520.9 - 848319 - - - -1.9319 - 3.311 0.563 - 233.6 1 2 0 -0.0042 20 0 0 0 7.72E+06 1.92E+07 - - - 4.5254 0.9981 221125_WJC_METTL3_EV_vs_WT_F05.21658.21658.3 1.81E-08 15/64 L.GNQLDGIHLLDPDVVAR.F sp|Q86U44|MTA70_HUMAN 1 1830.9588 0.02 72054 21658 3 1830.955822 611.3269 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 4.41 3521.3 - 710102 - - - -1.6325 - 2.982 0.583 - 255.5 1 1 0 -0.003 17 0 0 0 1.31E+07 7.19E+08 - - - 7.7993 0.9053 221125_WJC_METTL3_EV_vs_WT_F05.21660.21660.4 0.00181 Aug-84 K.K[136.11]LLHHLSDLALTLPT.D "sp|Q86U44|MTA70_HUMAN,tr|B4E349|B4E349_HUMAN,tr|F5H6D8|F5H6D8_HUMAN,tr|H0YFV6|H0YFV6_HUMAN,tr|B4DTN4|B4DTN4_HUMAN" 5 1678.9861 0.03 72056 21660 4 1678.980566 420.7538 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 6.92 3521.5 - 394985 - - - -3.3211 - 1.636 0.384 - 40.8 1 1 0 -0.0056 15 0 0 0 4.19E+05 1.21E+07 - - - 2.7429 0.9997 221125_WJC_METTL3_EV_vs_WT_F05.21666.21666.3 4.87E-06 18/72 R.IQEIIEQLDVTTSEYEK[136.11]EK[136.11].L "sp|P10809|CH60_HUMAN,tr|A0A7I2V2X6|A0A7I2V2X6_HUMAN,tr|A0A7I2YQK6|A0A7I2YQK6_HUMAN,tr|A0A7I2V599|A0A7I2V599_HUMAN" 4 2310.1813 0.32 72060 21666 3 2310.177513 771.0677 "60 kDa heat shock protein, mitochondrial OS=Homo sapiens OX=9606 GN=HSPD1 PE=1 SV=2" 4.14 3522.2 - 1.04E+06 - - - -1.6561 - 3.278 0.396 - 336.9 1 2 1 -0.0038 19 0 0 0 2.05E+08 6.50E+08 - - - 5.8707 1 221125_WJC_METTL3_EV_vs_WT_F05.21671.21671.3 1.75E-10 18/76 K.K[136.11]LGGSLADSYLDEGFLLDK[136.11]K[136.11].L "sp|P78371|TCPB_HUMAN,tr|F8VQ14|F8VQ14_HUMAN,tr|F5GWF6|F5GWF6_HUMAN" 3 2192.1791 0.21 72065 21671 3 2192.179256 731.7336 T-complex protein 1 subunit beta OS=Homo sapiens OX=9606 GN=CCT2 PE=1 SV=4 4.68 3522.9 - 547026 - - - 0.0707 - 3.514 0.606 - 408.8 1 2 0 0.0002 20 0 0 0 1.47E+06 6.86E+06 - - - 8.3452 0.9999 221125_WJC_METTL3_EV_vs_WT_F05.21691.21691.3 2.91E-07 22/80 R.K[136.11]HAASDVDLEIESLLNQQSTK[136.11].E "sp|Q86U44|MTA70_HUMAN,tr|F5H6D8|F5H6D8_HUMAN,tr|H0YFV6|H0YFV6_HUMAN,tr|B4DTN4|B4DTN4_HUMAN" 4 2341.2096 0 72076 21691 3 2341.204798 781.4105 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 4.75 3525.5 - 1.53E+06 - - - -2.0592 - 3.197 0.471 - 368.4 1 2 0 -0.0048 21 0 0 0 1.41E+05 3.02E+07 - - - 6.5762 0.9853 221125_WJC_METTL3_EV_vs_WT_F05.21712.21712.3 2.25E-05 20/64 L.GNQLDGIHLLDPDVVAR[166.11].F sp|Q86U44|MTA70_HUMAN 1 1840.9671 0.02 72083 21712 3 1840.959531 614.663 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 4.41 3528.4 - 1.69E+06 - - - -4.1011 - 3.082 0.532 - 201.5 1 1 0 -0.0076 17 0 0 0 1.31E+07 7.20E+08 - - - 7.3127 0.9999 221125_WJC_METTL3_EV_vs_WT_F05.21734.21734.3 7.27E-05 17/64 K.NVEQSSDLQDQLNHLLK.- "sp|Q96B45|BORC7_HUMAN,tr|A0A0B4J1R7|A0A0B4J1R7_HUMAN" 2 1979.9912 2.44 72095 21734 3 1979.98609 661.0044 BLOC-1-related complex subunit 7 OS=Homo sapiens OX=9606 GN=BORCS7 PE=3 SV=2 4.54 3531.1 - 976029 - - - -2.5975 - 2.461 0.478 - 186.6 1 2 0 -0.0051 17 0 0 0 2.09E+07 8.58E+06 - - - 6.1429 1 221125_WJC_METTL3_EV_vs_WT_F05.21738.21738.3 4.91E-09 19/92 R.ELFIEEIQAGSQGQAGASDSPSAR.S "sp|P39880|CUX1_HUMAN,tr|A0A2R8Y852|A0A2R8Y852_HUMAN,tr|A0A2R8YDI1|A0A2R8YDI1_HUMAN" 3 2447.1565 1.71 72097 21738 3 2447.147805 816.7261 Homeobox protein cut-like 1 OS=Homo sapiens OX=9606 GN=CUX1 PE=1 SV=3 4 3531.6 - 1.08E+06 - - - -3.5372 - 3.662 0.683 - 363.2 1 2 0 -0.0087 24 0 0 0 3.09E+07 1.81E+07 - - - 9.1671 1 221125_WJC_METTL3_EV_vs_WT_F05.21739.21739.3 1.06E-11 15/92 K.VIQNSTEC[160.03]TDAQQASLLPSVPALK.G tr|H7C0V5|H7C0V5_HUMAN 1 2569.3058 1.44 72098 21739 3 2569.298587 857.4425 ANKHD1-EIF4EBP3 readthrough (Fragment) OS=Homo sapiens OX=9606 GN=ANKHD1-EIF4EBP3 PE=4 SV=1 4.37 3531.8 - 613886 - - - -2.7949 - 2.836 0.672 - 138.6 1 2 0 -0.0072 24 0 0 0 1.23E+07 8.53E+06 - - - 8.4512 1 221125_WJC_METTL3_EV_vs_WT_F05.21749.21749.3 8.73E-12 22/92 R.ELFIEEIQAGSQGQAGASDSPSAR[166.11].S "sp|P39880|CUX1_HUMAN,tr|A0A2R8Y852|A0A2R8Y852_HUMAN,tr|A0A2R8YDI1|A0A2R8YDI1_HUMAN" 3 2457.1647 1.71 72102 21749 3 2457.163619 820.0622 Homeobox protein cut-like 1 OS=Homo sapiens OX=9606 GN=CUX1 PE=1 SV=3 4 3533.1 - 838224 - - - -0.4526 - 3.969 0.601 - 556.3 1 2 0 -0.0011 24 0 0 0 3.09E+07 1.81E+07 - - - 8.442 1 221125_WJC_METTL3_EV_vs_WT_F05.21754.21754.4 0.00154 18/132 R.DGAAYFYGPIFIHPEETEHEPTK.M "sp|Q86U86|PB1_HUMAN,tr|E7EVG2|E7EVG2_HUMAN" 2 2647.2231 1.9 72104 21754 4 2647.219862 662.813 Protein polybromo-1 OS=Homo sapiens OX=9606 GN=PBRM1 PE=1 SV=1 4.56 3533.7 - 710233 - - - -1.2171 - 3.437 0.529 - 166.6 1 2 0 -0.0032 23 0 0 0 2.83E+07 1.50E+07 - - - 4.2295 0.9999 221125_WJC_METTL3_EV_vs_WT_F05.21760.21760.3 8.88E-11 17/72 K.AKFPFGGLLDSAQASETSK.L "sp|Q9NSC2|SALL1_HUMAN,tr|H3BSM9|H3BSM9_HUMAN" 2 1952.9844 1.81 72107 21760 3 1952.983078 652.0021 Sal-like protein 1 OS=Homo sapiens OX=9606 GN=SALL1 PE=1 SV=2 6.11 3534.5 - 383598 - - - -0.6549 - 3.41 0.58 - 329 1 2 1 -0.0013 19 0 0 0 1.23E+07 6.81E+06 - - - 8.0199 0.8913 221125_WJC_METTL3_EV_vs_WT_F05.21764.21764.3 0.117 4/124 K.ESESC[160.03]DC[160.03]LQGFQLTHSLGGGTGSGMGTLLISK[136.11].L "sp|Q9BVA1|TBB2B_HUMAN,sp|Q13885|TBB2A_HUMAN" 2 3334.5359 0.59 72110 21764 3 3334.531114 1112.5193 Tubulin beta-2B chain OS=Homo sapiens OX=9606 GN=TUBB2B PE=1 SV=1 4.65 3535 - 438896 - - - -1.4437 - 1.111 0.156 - 12.3 1 2 0 -0.0048 32 0 0 0 4.54E+06 7.72E+06 - - - 0.5201 0.9982 221125_WJC_METTL3_EV_vs_WT_F05.21771.21771.3 7.51E-05 13/44 K.IEEIK[136.11]DFLLTAR[166.11].R "sp|P63173|RL38_HUMAN,tr|J3KT73|J3KT73_HUMAN,tr|J3QL01|J3QL01_HUMAN,tr|J3KSP2|J3KSP2_HUMAN" 4 1464.8307 1.41 72115 21771 3 1464.824681 489.2842 60S ribosomal protein L38 OS=Homo sapiens OX=9606 GN=RPL38 PE=1 SV=2 4.68 3536 - 328322 - - - -4.109 - 2.327 0.46 - 240.9 1 2 1 -0.006 12 0 0 0 1.14E+07 8.08E+06 - - - 6.0079 1 221125_WJC_METTL3_EV_vs_WT_F05.21772.21772.3 1.38E-11 15/104 K.HTGPGILSMANAGPNTNGSQFFIC[160.03]TAK.T "sp|P62937|PPIA_HUMAN,tr|C9J5S7|C9J5S7_HUMAN,tr|A0A7I2V4V1|A0A7I2V4V1_HUMAN,tr|F8WE65|F8WE65_HUMAN" 4 2790.3218 1.16 72116 21772 3 2790.319861 931.1145 Peptidyl-prolyl cis-trans isomerase A OS=Homo sapiens OX=9606 GN=PPIA PE=1 SV=2 8.23 3536.2 - 259892 - - - -0.6838 - 3.307 0.709 - 191 1 2 0 -0.0019 27 0 0 0 1.92E+06 1.65E+06 - - - 9.1958 1 221125_WJC_METTL3_EV_vs_WT_F05.21775.21775.4 2.70E-12 24/132 R.DGAAYFYGPIFIHPEETEHEPTK[136.11].M "sp|Q86U86|PB1_HUMAN,tr|E7EVG2|E7EVG2_HUMAN" 2 2655.2373 1.9 72117 21775 4 2655.227706 664.8166 Protein polybromo-1 OS=Homo sapiens OX=9606 GN=PBRM1 PE=1 SV=1 4.56 3536.6 - 799015 - - - -3.6072 - 3.667 0.687 - 386.4 1 2 0 -0.0096 23 0 0 0 2.83E+07 1.50E+07 - - - 5.624 0.9961 221125_WJC_METTL3_EV_vs_WT_F05.21776.21776.3 0.000992 6/124 K.ESESC[160.03]DC[160.03]LQGFQLTHSLGGGTGSGMGTLLISK.L "sp|Q9BVA1|TBB2B_HUMAN,sp|Q13885|TBB2A_HUMAN" 2 3326.5217 0.59 72118 21776 3 3326.510183 1109.8479 Tubulin beta-2B chain OS=Homo sapiens OX=9606 GN=TUBB2B PE=1 SV=1 4.65 3536.7 - 395230 - - - -3.4706 - 1.372 0.382 - 22.4 1 2 0 -0.0115 32 0 0 0 4.54E+06 7.72E+06 - - - 3.5233 0.9848 221125_WJC_METTL3_EV_vs_WT_F05.21781.21781.3 0.0333 13/44 K.IEEIKDFLLTAR.R "sp|P63173|RL38_HUMAN,tr|J3KT73|J3KT73_HUMAN,tr|J3QL01|J3QL01_HUMAN,tr|J3KSP2|J3KSP2_HUMAN" 4 1446.8082 1.4 72121 21781 3 1446.804413 483.2767 60S ribosomal protein L38 OS=Homo sapiens OX=9606 GN=RPL38 PE=1 SV=2 4.68 3537.4 - 598635 - - - -2.6382 - 1.88 0.261 - 105.2 1 2 1 -0.0038 12 0 0 0 1.13E+07 8.05E+06 - - - 3.1986 0.9995 221125_WJC_METTL3_EV_vs_WT_F05.21785.21785.4 0.00885 9/108 R.VIHLSNLPHSGYSDSAVLK[136.11].L "sp|P43243|MATR3_HUMAN,tr|B3KM87|B3KM87_HUMAN,tr|A8MXP9|A8MXP9_HUMAN,tr|D6RBK5|D6RBK5_HUMAN,tr|A0A0R4J2E8|A0A0R4J2E8_HUMAN,tr|H0Y8T4|H0Y8T4_HUMAN,tr|D6REM6|D6REM6_HUMAN" 7 2044.0833 0.75 72125 21785 4 2044.079645 512.0281 Matrin-3 OS=Homo sapiens OX=9606 GN=MATR3 PE=1 SV=2 6.89 3537.9 - 158312 - - - -1.7832 - 2.177 0.344 - 73.3 1 2 0 -0.0036 19 0 0 0 1.94E+06 2.59E+06 - - - 2.4823 1 221125_WJC_METTL3_EV_vs_WT_F05.21789.21789.3 2.98E-12 13/104 K.HTGPGILSMANAGPNTNGSQFFIC[160.03]TAK[136.11].T "sp|P62937|PPIA_HUMAN,tr|C9J5S7|C9J5S7_HUMAN,tr|A0A7I2V4V1|A0A7I2V4V1_HUMAN,tr|F8WE65|F8WE65_HUMAN" 4 2798.336 1.19 72127 21789 3 2798.327363 933.7859 Peptidyl-prolyl cis-trans isomerase A OS=Homo sapiens OX=9606 GN=PPIA PE=1 SV=2 8.23 3538.4 - 322860 - - - -3.0754 - 3.293 0.662 - 161.3 1 2 0 -0.0086 27 0 0 0 2.07E+06 1.75E+06 - - - 8.6602 0.9999 221125_WJC_METTL3_EV_vs_WT_F05.21792.21792.4 0.000475 10/108 R.VIHLSNLPHSGYSDSAVLK.L "sp|P43243|MATR3_HUMAN,tr|B3KM87|B3KM87_HUMAN,tr|A8MXP9|A8MXP9_HUMAN,tr|D6RBK5|D6RBK5_HUMAN,tr|A0A0R4J2E8|A0A0R4J2E8_HUMAN,tr|H0Y8T4|H0Y8T4_HUMAN,tr|D6REM6|D6REM6_HUMAN" 7 2036.0691 0.95 72130 21792 4 2036.065721 510.0245 Matrin-3 OS=Homo sapiens OX=9606 GN=MATR3 PE=1 SV=2 6.89 3538.8 - 196059 - - - -1.6547 - 2.431 0.478 - 89.3 1 2 0 -0.0034 19 0 0 0 2.17E+06 2.30E+06 - - - 3.6861 1 221125_WJC_METTL3_EV_vs_WT_F05.21797.21797.3 2.50E-12 28/84 R.THISDAVVASGAPLAILYDHQR.Q "sp|Q5VT06|CE350_HUMAN,tr|H0Y6Q4|H0Y6Q4_HUMAN" 2 2333.2128 0.52 72133 21797 3 2333.210824 778.7449 Centrosome-associated protein 350 OS=Homo sapiens OX=9606 GN=CEP350 PE=1 SV=1 5.91 3539.4 - 313813 - - - -0.8443 - 4.846 0.666 - 1141.2 1 2 0 -0.002 22 0 0 0 3.61E+06 7.00E+06 - - - 9.7062 0.9996 221125_WJC_METTL3_EV_vs_WT_F05.21799.21799.3 5.07E-07 Oct-84 R.EEYQPATPGLGMFVEVKDPEDK.V sp|Q9BVK6|TMED9_HUMAN 1 2478.1625 1.59 72135 21799 3 2478.158044 827.0614 Transmembrane emp24 domain-containing protein 9 OS=Homo sapiens OX=9606 GN=TMED9 PE=1 SV=2 4.08 3539.6 - 317063 - - - -1.7808 - 2.54 0.46 - 82 1 2 1 -0.0044 22 0 0 0 1.11E+07 7.00E+06 - - - 5.8773 1 221125_WJC_METTL3_EV_vs_WT_F05.21800.21800.4 2.02E-07 12/102 R.TDYHILNDPELSFLDAHK[136.11].N sp|Q9P2D1|CHD7_HUMAN 1 2135.0415 1.37 72136 21800 4 2135.039046 534.7676 Chromodomain-helicase-DNA-binding protein 7 OS=Homo sapiens OX=9606 GN=CHD7 PE=1 SV=3 4.63 3539.8 - 259935 - - - -1.1424 - 2.376 0.584 - 98.1 1 2 0 -0.0024 18 0 0 0 1.09E+07 7.97E+06 - - - 4.6049 0.9998 221125_WJC_METTL3_EV_vs_WT_F05.21801.21801.4 2.96E-06 14/102 R.RKDPELWGSVLLESNPYR.R "sp|Q00610|CLH1_HUMAN,tr|A0A087WVQ6|A0A087WVQ6_HUMAN" 2 2158.1171 2.18 72137 21801 4 2158.121453 540.5366 Clathrin heavy chain 1 OS=Homo sapiens OX=9606 GN=CLTC PE=1 SV=5 6.18 3539.9 - 208987 - - - 2.0156 - 2.784 0.524 - 153.4 1 2 1 0.0044 18 0 0 0 4.07E+06 1.86E+06 - - - 4.1364 0.9992 221125_WJC_METTL3_EV_vs_WT_F05.21802.21802.3 3.41E-07 Oct-76 K.GNPQGFNQGLDC[160.03]DVIVAEVR[166.11].S sp|Q86U44|MTA70_HUMAN 1 2197.0461 0.06 72138 21802 3 2198.047516 733.356 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 4.03 3540 - 158559 - - - 455.7847 - 2.216 0.571 - 131.4 1 2 0 1.0014 20 0 0 0 1.14E+05 1.95E+06 - - - 6.5591 1 221125_WJC_METTL3_EV_vs_WT_F05.21806.21806.4 2.76E-05 18/102 R.TDYHILNDPELSFLDAHK.N sp|Q9P2D1|CHD7_HUMAN 1 2127.0273 1.37 72140 21806 4 2127.024686 532.7641 Chromodomain-helicase-DNA-binding protein 7 OS=Homo sapiens OX=9606 GN=CHD7 PE=1 SV=3 4.63 3540.7 - 545281 - - - -1.2219 - 2.85 0.475 - 251.5 1 2 0 -0.0026 18 0 0 0 1.09E+07 7.97E+06 - - - 3.7184 1 221125_WJC_METTL3_EV_vs_WT_F05.21807.21807.4 3.42E-09 31/126 R.THISDAVVASGAPLAILYDHQR.Q "sp|Q5VT06|CE350_HUMAN,tr|H0Y6Q4|H0Y6Q4_HUMAN" 2 2333.2128 0.74 72141 21807 4 2333.211794 584.3105 Centrosome-associated protein 350 OS=Homo sapiens OX=9606 GN=CEP350 PE=1 SV=1 5.91 3540.8 - 1.23E+06 - - - -0.4286 - 4.427 0.666 - 933.6 1 2 0 -0.001 22 0 0 0 9.16E+06 1.24E+07 - - - 5.5094 0.9999 221125_WJC_METTL3_EV_vs_WT_F05.21808.21808.4 4.22E-07 18/126 R.THISDAVVASGAPLAILYDHQR[166.11].Q "sp|Q5VT06|CE350_HUMAN,tr|H0Y6Q4|H0Y6Q4_HUMAN" 2 2343.2211 0.3 72142 21808 4 2343.215162 586.8125 Centrosome-associated protein 350 OS=Homo sapiens OX=9606 GN=CEP350 PE=1 SV=1 5.91 3540.9 - 662190 - - - -2.5188 - 2.978 0.528 - 166.4 1 2 0 -0.0059 22 0 0 0 1.05E+07 3.56E+07 - - - 4.1771 0.9999 221125_WJC_METTL3_EV_vs_WT_F05.21810.21810.3 7.31E-07 24/100 K.GGVSAVAGGVTAVGSAVVNK[136.11]VPLTGK[136.11].K sp|Q8WUH6|TM263_HUMAN 1 2310.3242 0.88 72144 21810 3 2310.323158 771.1153 Transmembrane protein 263 OS=Homo sapiens OX=9606 GN=TMEM263 PE=1 SV=1 10 3541.2 - 389657 - - - -0.4489 - 4.024 0.515 - 423.1 1 2 1 -0.001 26 0 0 0 3.47E+07 3.97E+07 - - - 7.4846 0.9999 221125_WJC_METTL3_EV_vs_WT_F05.21811.21811.3 5.46E-07 14/84 R.EEYQPATPGLGMFVEVK[136.11]DPEDK[136.11].V sp|Q9BVK6|TMED9_HUMAN 1 2494.1909 1.55 72145 21811 3 2494.189449 832.4042 Transmembrane emp24 domain-containing protein 9 OS=Homo sapiens OX=9606 GN=TMED9 PE=1 SV=2 4.08 3541.3 - 332733 - - - -0.5645 - 2.784 0.575 - 172.6 1 2 1 -0.0014 22 0 0 0 1.10E+07 7.09E+06 - - - 7.3778 0.8464 221125_WJC_METTL3_EV_vs_WT_F05.21812.21812.3 0.0734 May-68 K.TPNTEQQTPLFQVISPQR.L sp|Q8IZD4|DCP1B_HUMAN 1 2083.0698 1.51 72146 21812 3 2083.062502 695.3639 mRNA-decapping enzyme 1B OS=Homo sapiens OX=9606 GN=DCP1B PE=1 SV=2 5.66 3541.4 - 80199.6 - - - -3.5121 - 1.326 0.168 - 26.5 1 2 0 -0.0073 18 0 0 0 3.34E+06 2.21E+06 - - - 1.1136 1 221125_WJC_METTL3_EV_vs_WT_F05.21820.21820.3 2.67E-08 24/108 K.TPGAVNAC[160.03]HLSC[160.03]SALLQDNIADAVAC[160.03]AK.R sp|P61626|LYSC_HUMAN 1 2926.3735 424.68 72151 21820 3 2926.376994 976.4651 Lysozyme C OS=Homo sapiens OX=9606 GN=LYZ PE=1 SV=1 5.18 3542.5 - 372409 - - - 1.1779 - 4.316 0.675 - 542.6 1 2 0 0.0034 28 0 0 0 2.12E+07 4.98E+04 - - - 9.4289 1 221125_WJC_METTL3_EV_vs_WT_F05.21822.21822.3 0.000933 15/80 R.ETEGGTVLTATTSELEAINKR.V sp|Q9UQE7|SMC3_HUMAN 1 2219.1281 0.88 72153 21822 3 2219.129207 740.7167 Structural maintenance of chromosomes protein 3 OS=Homo sapiens OX=9606 GN=SMC3 PE=1 SV=2 4.49 3542.7 - 284929 - - - 0.4894 - 3.427 0.598 - 164.3 1 2 0 0.0011 21 0 0 0 1.38E+07 1.58E+07 - - - 8.1597 1 221125_WJC_METTL3_EV_vs_WT_F05.21823.21823.3 6.50E-08 13/104 R.AVQTR[166.11]PVLQPQPGSLNSSIWDGSEVLR[166.11].R sp|Q86TB9|PATL1_HUMAN 1 2953.5525 1.41 72154 21823 3 2953.544336 985.5248 Protein PAT1 homolog 1 OS=Homo sapiens OX=9606 GN=PATL1 PE=1 SV=2 6.12 3542.9 - 241876 - - - -2.7502 - 3.064 0.664 - 101.7 1 2 0 -0.0081 27 0 0 0 2.03E+06 1.44E+06 - - - 8.5168 0.9783 221125_WJC_METTL3_EV_vs_WT_F05.21825.21825.4 0.225 Jul-96 K.LSDFDR[166.11]EHFSEVFVDLK[136.11].W sp|Q8IZH2|XRN1_HUMAN 1 2100.0283 1.06 72156 21825 4 2100.029398 526.0143 5'-3' exoribonuclease 1 OS=Homo sapiens OX=9606 GN=XRN1 PE=1 SV=1 4.43 3543.1 - 85991.3 - - - 0.5271 - 1.271 0.238 - 33.8 1 2 1 0.0011 17 0 0 0 6.61E+05 6.23E+05 - - - 1.3805 1 221125_WJC_METTL3_EV_vs_WT_F05.21829.21829.3 2.01E-10 22/80 R.ETEGGTVLTATTSELEAINK[136.11]R[166.11].V sp|Q9UQE7|SMC3_HUMAN 1 2237.1506 0.88 72158 21829 3 2237.15064 746.7241 Structural maintenance of chromosomes protein 3 OS=Homo sapiens OX=9606 GN=SMC3 PE=1 SV=2 4.49 3543.6 - 691026 - - - 0.0219 - 4.19 0.661 - 778.7 1 2 0 0 21 0 0 0 1.38E+07 1.58E+07 - - - 9.3443 0.9971 221125_WJC_METTL3_EV_vs_WT_F05.21830.21830.3 1.47E-08 16/88 Y.HGSIVGAYAGYPSQFVPGLDPSK.S sp|Q9H7S9|ZN703_HUMAN 1 2346.1644 1.59 72159 21830 3 2346.159508 783.0621 Zinc finger protein 703 OS=Homo sapiens OX=9606 GN=ZNF703 PE=1 SV=1 6.74 3543.7 - 180407 - - - -2.1051 - 3.018 0.579 - 211.9 1 1 0 -0.0049 23 0 0 0 2.89E+06 1.82E+06 - - - 7.5852 0.9978 221125_WJC_METTL3_EV_vs_WT_F05.21833.21833.2 0.0318 18-Jun R.GMQDLVEDFK.N sp|P02538|K2C6A_HUMAN 1 1180.5434 11.67 72162 21833 2 1180.544251 591.279 "Keratin, type II cytoskeletal 6A OS=Homo sapiens OX=9606 GN=KRT6A PE=1 SV=3" 4.03 3544.1 - 151778 - - - 0.6997 - 1.335 0.269 - 97.1 1 2 0 0.0008 10 0 0 0 2.69E+06 2.30E+05 - - - 1.8341 1 221125_WJC_METTL3_EV_vs_WT_F05.21834.21834.3 2.75E-05 Aug-52 K.VDLKPLLSSLSANK.E "sp|Q9NRA8|4ET_HUMAN,tr|B1AKL4|B1AKL4_HUMAN,tr|B0QYZ7|B0QYZ7_HUMAN" 3 1483.861 1.1 72163 21834 3 1483.861921 495.6276 Eukaryotic translation initiation factor 4E transporter OS=Homo sapiens OX=9606 GN=EIF4ENIF1 PE=1 SV=2 8.56 3544.2 - 140145 - - - 0.6247 - 1.877 0.517 - 62.4 1 2 0 0.0009 14 0 0 0 2.32E+06 2.12E+06 - - - 5.9772 0.9999 221125_WJC_METTL3_EV_vs_WT_F05.21837.21837.4 4.30E-08 23/150 K.GGVSAVAGGVTAVGSAVVNK[136.11]VPLTGK[136.11].K sp|Q8WUH6|TM263_HUMAN 1 2310.3242 0.74 72164 21837 4 2310.323449 578.5883 Transmembrane protein 263 OS=Homo sapiens OX=9606 GN=TMEM263 PE=1 SV=1 10 3544.6 - 613824 - - - -0.3229 - 3.72 0.618 - 295 1 2 1 -0.0007 26 0 0 0 5.16E+06 6.94E+06 - - - 5.0193 0.9869 221125_WJC_METTL3_EV_vs_WT_F05.21841.21841.4 0.000525 10/102 R.R[166.11]K[136.11]DPELWGSVLLESNPYR[166.11].R "sp|Q00610|CLH1_HUMAN,tr|A0A087WVQ6|A0A087WVQ6_HUMAN" 2 2186.1478 2.22 72168 21841 4 2186.148752 547.5442 Clathrin heavy chain 1 OS=Homo sapiens OX=9606 GN=CLTC PE=1 SV=5 6.18 3545.1 - 193273 - - - 0.4158 - 2.058 0.241 - 65.3 1 2 1 0.0009 18 0 0 0 4.07E+06 1.83E+06 - - - 1.5706 0.9989 221125_WJC_METTL3_EV_vs_WT_F05.21847.21847.3 6.47E-11 16/88 R.SVISHSVTSDMQTIEQESPIMAK.P "sp|Q9NP61|ARFG3_HUMAN,tr|H0Y6A0|H0Y6A0_HUMAN" 2 2517.2091 0.96 72172 21847 3 2517.208631 840.077 ADP-ribosylation factor GTPase-activating protein 3 OS=Homo sapiens OX=9606 GN=ARFGAP3 PE=1 SV=1 4.65 3546 - 323072 - - - -0.1823 - 2.992 0.639 - 187.9 1 1 0 -0.0005 23 0 0 0 9.26E+06 9.65E+06 - - - 8.2351 0.9994 221125_WJC_METTL3_EV_vs_WT_F05.21851.21851.3 0.00574 Jul-52 K.VDLK[136.11]PLLSSLSANK[136.11].E "sp|Q9NRA8|4ET_HUMAN,tr|B1AKL4|B1AKL4_HUMAN,tr|B0QYZ7|B0QYZ7_HUMAN" 3 1499.8894 1.1 72176 21851 3 1499.891797 500.9704 Eukaryotic translation initiation factor 4E transporter OS=Homo sapiens OX=9606 GN=EIF4ENIF1 PE=1 SV=2 8.56 3546.5 - 177364 - - - 1.6021 - 1.318 0.42 - 44.6 1 2 0 0.0024 14 0 0 0 2.32E+06 2.12E+06 - - - 3.9557 0.9814 221125_WJC_METTL3_EV_vs_WT_F05.21855.21855.3 2.78E-09 15/72 A.TISANGDKEIGNIISDAMK.K "sp|P10809|CH60_HUMAN,tr|A0A7I2V599|A0A7I2V599_HUMAN,tr|E7EXB4|E7EXB4_HUMAN,tr|A0A7I2YQ71|A0A7I2YQ71_HUMAN,tr|E7ESH4|E7ESH4_HUMAN,tr|A0A7I2V5M1|A0A7I2V5M1_HUMAN,tr|A0A7I2V5K3|A0A7I2V5K3_HUMAN,tr|A0A7I2V369|A0A7I2V369_HUMAN" 8 1975.9885 1.42 72178 21855 3 1975.993923 659.6701 "60 kDa heat shock protein, mitochondrial OS=Homo sapiens OX=9606 GN=HSPD1 PE=1 SV=2" 4.56 3546.9 - 1.13E+06 - - - 2.7667 - 3.042 0.595 - 107.7 1 1 1 0.0055 19 0 0 0 2.38E+07 1.68E+07 - - - 7.9054 1 221125_WJC_METTL3_EV_vs_WT_F05.21856.21856.3 7.55E-14 20/92 R.TDDEVVQR[166.11]EEEAIQLDGLNASQIR[166.11].E "sp|P14625|ENPL_HUMAN,tr|A0A7P0Z405|A0A7P0Z405_HUMAN,tr|A0A7P0T823|A0A7P0T823_HUMAN,tr|A0A7P0TAE1|A0A7P0TAE1_HUMAN,tr|H0YIV0|H0YIV0_HUMAN,tr|A0A7P0T8R3|A0A7P0T8R3_HUMAN,tr|A0A7P0T885|A0A7P0T885_HUMAN,tr|A0A7P0TAY2|A0A7P0TAY2_HUMAN,tr|A0A087WT78|A0A087WT78_HUMAN,tr|A0A7P0TBC2|A0A7P0TBC2_HUMAN,tr|A0A7P0TAT8|A0A7P0TAT8_HUMAN" 11 2747.3477 1.14 72179 21856 3 2747.35268 916.7898 Endoplasmin OS=Homo sapiens OX=9606 GN=HSP90B1 PE=1 SV=1 3.95 3547.1 - 294716 - - - 1.8232 - 4.142 0.651 - 447.7 1 2 1 0.005 24 0 0 0 3.22E+06 2.81E+06 - - - 9.0974 1 221125_WJC_METTL3_EV_vs_WT_F05.21858.21858.3 7.14E-14 22/92 R.TDDEVVQREEEAIQLDGLNASQIR.E "sp|P14625|ENPL_HUMAN,tr|A0A7P0Z405|A0A7P0Z405_HUMAN,tr|A0A7P0T823|A0A7P0T823_HUMAN,tr|A0A7P0TAE1|A0A7P0TAE1_HUMAN,tr|H0YIV0|H0YIV0_HUMAN,tr|A0A7P0T8R3|A0A7P0T8R3_HUMAN,tr|A0A7P0T885|A0A7P0T885_HUMAN,tr|A0A7P0TAY2|A0A7P0TAY2_HUMAN,tr|A0A087WT78|A0A087WT78_HUMAN,tr|A0A7P0TBC2|A0A7P0TBC2_HUMAN,tr|A0A7P0TAT8|A0A7P0TAT8_HUMAN" 11 2727.3311 1.14 72181 21858 3 2727.333739 910.1177 Endoplasmin OS=Homo sapiens OX=9606 GN=HSP90B1 PE=1 SV=1 3.95 3547.3 - 368109 - - - 0.9562 - 4.344 0.752 - 600 1 2 1 0.0026 24 0 0 0 3.22E+06 2.81E+06 - - - 10.3348 0.9942 221125_WJC_METTL3_EV_vs_WT_F05.21864.21864.3 1.49E-08 21/72 A.TISANGDK[136.11]EIGNIISDAMK[136.11].K "sp|P10809|CH60_HUMAN,tr|A0A7I2V599|A0A7I2V599_HUMAN,tr|E7EXB4|E7EXB4_HUMAN,tr|A0A7I2YQ71|A0A7I2YQ71_HUMAN,tr|E7ESH4|E7ESH4_HUMAN,tr|A0A7I2V5M1|A0A7I2V5M1_HUMAN,tr|A0A7I2V5K3|A0A7I2V5K3_HUMAN,tr|A0A7I2V369|A0A7I2V369_HUMAN" 8 1992.0169 1.42 72185 21864 3 1992.017964 665.0129 "60 kDa heat shock protein, mitochondrial OS=Homo sapiens OX=9606 GN=HSPD1 PE=1 SV=2" 4.56 3548 - 1.15E+06 - - - 0.5562 - 3.297 0.576 - 256.9 1 1 1 0.0011 19 0 0 0 2.38E+07 1.68E+07 - - - 7.8925 1 221125_WJC_METTL3_EV_vs_WT_F05.21868.21868.3 3.86E-10 14/76 K.GHLDAELDAYMAQTDPETND.- "sp|Q9Y3Y2|CHTOP_HUMAN,tr|X6R700|X6R700_HUMAN" 2 2204.9168 - 72189 21868 3 2204.91759 735.9795 Chromatin target of PRMT1 protein OS=Homo sapiens OX=9606 GN=CHTOP PE=1 SV=2 3.81 3548.5 - 186503 - - - 0.3551 - 3.208 0.666 - 241 1 2 0 0.0008 20 0 0 0 - - - - - 8.7929 1 221125_WJC_METTL3_EV_vs_WT_F05.21875.21875.3 1.45E-12 23/88 K.VTDFGDK[136.11]VEDPTFLNQLQSGVNR[166.11].W "sp|Q14204|DYHC1_HUMAN,tr|A0A7P0T8N2|A0A7P0T8N2_HUMAN,tr|A0A7P0T9C4|A0A7P0T9C4_HUMAN,tr|A0A7P0TBJ7|A0A7P0TBJ7_HUMAN,tr|A0A804HHY6|A0A804HHY6_HUMAN,tr|A0A7P0T9K2|A0A7P0T9K2_HUMAN,tr|A0A7P0TB64|A0A7P0TB64_HUMAN,tr|A0A2R8Y706|A0A2R8Y706_HUMAN,tr|A0A7P0T916|A0A7P0T916_HUMAN,tr|A0A7P0TB75|A0A7P0TB75_HUMAN,tr|A0A7P0T8W5|A0A7P0T8W5_HUMAN,tr|A0A7P0T9S3|A0A7P0T9S3_HUMAN,tr|A0A7P0TAF3|A0A7P0TAF3_HUMAN,tr|A0A7P0T9F1|A0A7P0T9F1_HUMAN,tr|A0A7P0TAW9|A0A7P0TAW9_HUMAN,tr|A0A2R8YGC7|A0A2R8YGC7_HUMAN,tr|A0A7P0TA13|A0A7P0TA13_HUMAN,tr|A0A7P0T934|A0A7P0T934_HUMAN,tr|A0A7P0TAV5|A0A7P0TAV5_HUMAN,tr|A0A7P0T9Y3|A0A7P0T9Y3_HUMAN,tr|A0A7P0T7V5|A0A7P0T7V5_HUMAN,tr|A0A7P0T9R4|A0A7P0T9R4_HUMAN,tr|A0A2R8Y5T0|A0A2R8Y5T0_HUMAN,tr|A0A7P0T990|A0A7P0T990_HUMAN,tr|A0A7P0T942|A0A7P0T942_HUMAN,tr|A0A2R8YFZ7|A0A2R8YFZ7_HUMAN,tr|A0A7P0T825|A0A7P0T825_HUMAN,tr|A0A2R8Y6H2|A0A2R8Y6H2_HUMAN,tr|A0A7P0TBC9|A0A7P0TBC9_HUMAN,tr|A0A7P0TAM4|A0A7P0TAM4_HUMAN" 30 2596.2888 0.91 72194 21875 3 2596.291176 866.4369 Cytoplasmic dynein 1 heavy chain 1 OS=Homo sapiens OX=9606 GN=DYNC1H1 PE=1 SV=5 4.23 3549.4 - 618133 - - - 0.909 - 4.336 0.666 - 550.1 1 2 1 0.0024 23 0 0 0 1.12E+07 1.23E+07 - - - 9.406 0.9985 221125_WJC_METTL3_EV_vs_WT_F05.21884.21884.2 5.39E-05 Jun-38 K.SSATSGDIWPGLSAYDNSPR.S "sp|Q9NYF8|BCLF1_HUMAN,tr|E9PKI6|E9PKI6_HUMAN,tr|A0A1W2PQ43|A0A1W2PQ43_HUMAN,tr|E9PK91|E9PK91_HUMAN,tr|E9PJA7|E9PJA7_HUMAN,tr|E9PK09|E9PK09_HUMAN,tr|E9PQN2|E9PQN2_HUMAN" 7 2079.9498 10.15 72201 21884 2 2079.956112 1040.9822 Bcl-2-associated transcription factor 1 OS=Homo sapiens OX=9606 GN=BCLAF1 PE=1 SV=2 4.21 3550.6 - 84936.9 - - - 3.053 - 1.259 0.528 - 32.5 1 2 0 0.0063 20 0 0 0 9.32E+06 9.19E+05 - - - 3.5051 0.814 221125_WJC_METTL3_EV_vs_WT_F05.21886.21886.3 0.204 Oct-60 R.DGLK[136.11]LMLLLEVISGER[166.11].L "sp|O43707|ACTN4_HUMAN,sp|P12814|ACTN1_HUMAN,tr|A0A804HK61|A0A804HK61_HUMAN,tr|A0A804HIN7|A0A804HIN7_HUMAN,tr|G3V5M4|G3V5M4_HUMAN,tr|A0A804HLF4|A0A804HLF4_HUMAN,tr|A0A804HIY0|A0A804HIY0_HUMAN,tr|A0A7I2V4Y4|A0A7I2V4Y4_HUMAN,tr|A0A804HII9|A0A804HII9_HUMAN,tr|A0A804HJQ9|A0A804HJQ9_HUMAN,tr|F5GXS2|F5GXS2_HUMAN,tr|A0A804HKE2|A0A804HKE2_HUMAN,tr|G3V2N5|G3V2N5_HUMAN,tr|A0A804HLD0|A0A804HLD0_HUMAN,tr|H7C144|H7C144_HUMAN" 15 1803.0295 0 72202 21886 3 1803.034789 602.0171 Alpha-actinin-4 OS=Homo sapiens OX=9606 GN=ACTN4 PE=1 SV=2 4.68 3550.8 - 588593 - - - 2.9462 - 1.767 0.147 - 119.3 1 2 1 0.0053 16 0 0 0 3.14E+06 8.48E+08 - - - 1.6381 0.9996 221125_WJC_METTL3_EV_vs_WT_F05.21888.21888.3 9.12E-08 Nov-88 K.DGSTTAGNSSQVSDGAAAILLAR.R "sp|P09110|THIK_HUMAN,tr|C9JDE9|C9JDE9_HUMAN,tr|H7C131|H7C131_HUMAN" 3 2161.0611 0.56 72204 21888 3 2161.072941 721.361 "3-ketoacyl-CoA thiolase, peroxisomal OS=Homo sapiens OX=9606 GN=ACAA1 PE=1 SV=2" 4.21 3551.1 - 267243 - - - 5.4774 - 2.534 0.577 - 129.9 1 2 0 0.0118 23 0 0 0 2.09E+06 3.75E+06 - - - 7.151 1 221125_WJC_METTL3_EV_vs_WT_F05.21891.21891.3 2.57E-10 14/84 R.DYEVSDSAPHLEGLAEFQENVR.K sp|Q9HBM1|SPC25_HUMAN 1 2504.1456 2.65 72207 21891 3 2504.147187 835.7225 Kinetochore protein Spc25 OS=Homo sapiens OX=9606 GN=SPC25 PE=1 SV=1 4.08 3551.5 - 164816 - - - 0.6489 - 3.06 0.724 - 108.5 1 2 0 0.0016 22 0 0 0 2.18E+07 8.24E+06 - - - 9.263 0.9871 221125_WJC_METTL3_EV_vs_WT_F05.21893.21893.3 0.00517 May-76 K.SSATSGDIWPGLSAYDNSPR[166.11].S "sp|Q9NYF8|BCLF1_HUMAN,tr|E9PKI6|E9PKI6_HUMAN,tr|A0A1W2PQ43|A0A1W2PQ43_HUMAN,tr|E9PK91|E9PK91_HUMAN,tr|E9PJA7|E9PJA7_HUMAN,tr|E9PK09|E9PK09_HUMAN,tr|E9PQN2|E9PQN2_HUMAN" 7 2089.958 4.85 72209 21893 3 2089.972968 697.66 Bcl-2-associated transcription factor 1 OS=Homo sapiens OX=9606 GN=BCLAF1 PE=1 SV=2 4.21 3551.7 - 93896 - - - 7.1466 - 1.371 0.469 - 23.9 1 2 0 0.0149 20 0 0 0 1.77E+07 3.66E+06 - - - 4.5303 1 221125_WJC_METTL3_EV_vs_WT_F05.21901.21901.2 1.96E-09 Dec-32 R.DQSAVVVQGLPEGVAFK.H "sp|P78347|GTF2I_HUMAN,tr|A0A494C1K3|A0A494C1K3_HUMAN" 2 1742.9203 1.2 72215 21901 2 1742.924433 872.4674 General transcription factor II-I OS=Homo sapiens OX=9606 GN=GTF2I PE=1 SV=2 4.37 3552.8 - 134037 - - - 2.3713 - 2.714 0.648 - 319.8 1 2 0 0.0041 17 0 0 0 9.46E+06 7.89E+06 - - - 6.2805 0.9547 221125_WJC_METTL3_EV_vs_WT_F05.21903.21903.3 0.142 Jul-72 R.GNGTSMISLIIPPK[136.11]DQISR[166.11].V "sp|P62495|ERF1_HUMAN,tr|D6RCB3|D6RCB3_HUMAN" 2 2044.1106 0.95 72217 21903 3 2044.111769 682.3775 Eukaryotic peptide chain release factor subunit 1 OS=Homo sapiens OX=9606 GN=ETF1 PE=1 SV=3 8.75 3553.1 - 101735 - - - 0.5812 - 1.552 0.195 - 40 1 2 1 0.0012 19 0 0 0 1.28E+06 1.35E+06 - - - 1.7936 0.9998 221125_WJC_METTL3_EV_vs_WT_F05.21907.21907.3 1.55E-06 23/84 K.DSGPLPTPPGVSLLGEPPK[136.11]DYR[166.11].L "tr|E9PAU2|E9PAU2_HUMAN,tr|A0A087WZ13|A0A087WZ13_HUMAN" 2 2309.2022 0.98 72220 21907 3 2309.206574 770.7414 Ribonucleoprotein PTB-binding 1 OS=Homo sapiens OX=9606 GN=RAVER1 PE=1 SV=1 4.56 3553.6 - 2.09E+06 - - - 1.8803 - 2.97 0.53 - 317.6 1 2 1 0.0043 22 0 0 0 6.40E+08 6.52E+08 - - - 7.0286 0.9998 221125_WJC_METTL3_EV_vs_WT_F05.21909.21909.3 7.56E-09 23/84 K.DSGPLPTPPGVSLLGEPPKDYR.L "tr|E9PAU2|E9PAU2_HUMAN,tr|A0A087WZ13|A0A087WZ13_HUMAN" 2 2291.1798 0.98 72221 21909 3 2291.184233 764.7339 Ribonucleoprotein PTB-binding 1 OS=Homo sapiens OX=9606 GN=RAVER1 PE=1 SV=1 4.56 3553.8 - 1.68E+06 - - - 1.9514 - 2.73 0.535 - 363.2 1 2 1 0.0045 22 0 0 0 6.39E+08 6.49E+08 - - - 6.8845 0.9774 221125_WJC_METTL3_EV_vs_WT_F05.21913.21913.2 0.245 30-Aug R.DGLK[136.11]LMLLLEVISGER[166.11].L "sp|O43707|ACTN4_HUMAN,sp|P12814|ACTN1_HUMAN,tr|A0A804HK61|A0A804HK61_HUMAN,tr|A0A804HIN7|A0A804HIN7_HUMAN,tr|G3V5M4|G3V5M4_HUMAN,tr|A0A804HLF4|A0A804HLF4_HUMAN,tr|A0A804HIY0|A0A804HIY0_HUMAN,tr|A0A7I2V4Y4|A0A7I2V4Y4_HUMAN,tr|A0A804HII9|A0A804HII9_HUMAN,tr|A0A804HJQ9|A0A804HJQ9_HUMAN,tr|F5GXS2|F5GXS2_HUMAN,tr|A0A804HKE2|A0A804HKE2_HUMAN,tr|G3V2N5|G3V2N5_HUMAN,tr|A0A804HLD0|A0A804HLD0_HUMAN,tr|H7C144|H7C144_HUMAN" 15 1803.0295 0.001 72225 21913 2 1803.033574 902.522 Alpha-actinin-4 OS=Homo sapiens OX=9606 GN=ACTN4 PE=1 SV=2 4.68 3554.3 - 220372 - - - 2.2723 - 1.753 0.3 - 178.6 1 2 1 0.0041 16 0 0 0 0.00E+00 4.58E+07 - - - 2.6356 1 221125_WJC_METTL3_EV_vs_WT_F05.21919.21919.3 1.32E-13 15/92 R.NGPGFHNDIDSNSTIQEILIPASK.V sp|Q96I24|FUBP3_HUMAN 1 2566.2663 2.13 72229 21919 3 2566.262421 856.4294 Far upstream element-binding protein 3 OS=Homo sapiens OX=9606 GN=FUBP3 PE=1 SV=2 4.54 3555.1 - 384595 - - - -1.5295 - 3.342 0.712 - 128.7 1 2 0 -0.0039 24 0 0 0 7.52E+07 3.53E+07 - - - 9.2794 1 221125_WJC_METTL3_EV_vs_WT_F05.21920.21920.4 7.83E-05 10/108 R.GLLQDDAHPTLVTYADHSK[136.11].L "sp|Q86U44|MTA70_HUMAN,tr|F5H6D8|F5H6D8_HUMAN,tr|H0YFV6|H0YFV6_HUMAN,tr|B4DTN4|B4DTN4_HUMAN" 4 2088.0367 0.001 72230 21920 4 2088.038701 523.0165 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 5.13 3555.2 - 204351 - - - 0.9425 - 2.23 0.52 - 97.7 1 2 0 0.002 19 0 0 0 0.00E+00 7.11E+06 - - - 4.0228 1 221125_WJC_METTL3_EV_vs_WT_F05.21923.21923.3 1.66E-08 20/80 K.R[166.11]NQDLAPNSAEQASILSLVTK[136.11].L "sp|Q12905|ILF2_HUMAN,tr|B4DY09|B4DY09_HUMAN,tr|X6R6Z1|X6R6Z1_HUMAN,tr|A0A0A0MRL0|A0A0A0MRL0_HUMAN" 4 2272.2142 1.63 72231 21923 3 2272.214564 758.412 Interleukin enhancer-binding factor 2 OS=Homo sapiens OX=9606 GN=ILF2 PE=1 SV=2 6.07 3555.7 - 724818 - - - 0.1628 - 3.539 0.587 - 327.7 1 2 0 0.0004 21 0 0 0 2.89E+07 1.77E+07 - - - 8.1144 1 221125_WJC_METTL3_EV_vs_WT_F05.21924.21924.3 1.23E-05 Sep-88 K.LTETVVTEYLNSGNANEAVNGVR.E "sp|P78344|IF4G2_HUMAN,tr|E9PKF8|E9PKF8_HUMAN,tr|H0Y3P2|H0Y3P2_HUMAN,tr|D3DQV9|D3DQV9_HUMAN" 4 2449.2085 7.99 72232 21924 3 2449.212609 817.4101 Eukaryotic translation initiation factor 4 gamma 2 OS=Homo sapiens OX=9606 GN=EIF4G2 PE=1 SV=1 4.25 3555.8 - 234533 - - - 1.6793 - 2.935 0.547 - 61.5 1 2 0 0.0041 23 0 0 0 5.66E+06 7.08E+05 - - - 7.1633 1 221125_WJC_METTL3_EV_vs_WT_F05.21929.21929.2 2.46E-07 13/32 R.DQSAVVVQGLPEGVAFK[136.11].H "sp|P78347|GTF2I_HUMAN,tr|A0A494C1K3|A0A494C1K3_HUMAN" 2 1750.9345 1.2 72235 21929 2 1750.935048 876.4745 General transcription factor II-I OS=Homo sapiens OX=9606 GN=GTF2I PE=1 SV=2 4.37 3556.5 - 237532 - - - 0.313 - 2.781 0.607 - 457.5 1 2 0 0.0005 17 0 0 0 9.46E+06 7.89E+06 - - - 6.0388 0.9985 221125_WJC_METTL3_EV_vs_WT_F05.21931.21931.2 0.237 14-Jun R.LTILELER[166.11].E sp|Q569K6|CC157_HUMAN 1 995.5891 0 72237 21931 2 995.588233 498.8018 Coiled-coil domain-containing protein 157 OS=Homo sapiens OX=9606 GN=CCDC157 PE=1 SV=3 4.53 3556.8 - 182522 - - - -0.8377 - 1.537 0.238 - 106.1 1 2 0 -0.0008 8 0 0 0 9.86E+04 4.69E+07 - - - 2.095 1 221125_WJC_METTL3_EV_vs_WT_F05.21932.21932.3 6.37E-05 Sep-84 R.DVPEDVAQEMVESGYVC[160.03]EGDHK.T "sp|Q9H4A3|WNK1_HUMAN,tr|F5GWT4|F5GWT4_HUMAN" 2 2492.0472 1.97 72238 21932 3 2492.050367 831.6897 Serine\threonine-protein kinase WNK1 OS=Homo sapiens OX=9606 GN=WNK1 PE=1 SV=2 3.95 3556.9 - 170446 - - - 1.2829 - 2.052 0.574 - 59.3 1 2 0 0.0032 22 0 0 0 1.83E+07 9.28E+06 - - - 6.6428 0.9999 221125_WJC_METTL3_EV_vs_WT_F05.21940.21940.3 1.46E-06 13/88 R.EGIAMDQLLSQSLPNDGDEK[136.11]YEK[136.11].T sp|Q9BRP1|PDD2L_HUMAN 1 2595.2345 0.53 72242 21940 3 2595.236895 866.0854 Programmed cell death protein 2-like OS=Homo sapiens OX=9606 GN=PDCD2L PE=1 SV=1 4.02 3558 - 353334 - - - 0.9178 - 2.847 0.538 - 126.3 1 2 1 0.0024 23 0 0 0 4.76E+06 8.93E+06 - - - 6.992 1 221125_WJC_METTL3_EV_vs_WT_F05.21942.21942.3 3.22E-08 Dec-72 R.DTPENNPDTPFDFTPENYK.R "sp|P19404|NDUV2_HUMAN,tr|E7EPT4|E7EPT4_HUMAN" 2 2239.9546 1.31 72244 21942 3 2239.954706 747.6588 "NADH dehydrogenase [ubiquinone] flavoprotein 2, mitochondrial OS=Homo sapiens OX=9606 GN=NDUFV2 PE=1 SV=2" 3.77 3558.2 - 215162 - - - 0.0594 - 2.307 0.604 - 133.7 1 2 0 0.0001 19 0 0 0 4.85E+06 3.69E+06 - - - 7.3277 1 221125_WJC_METTL3_EV_vs_WT_F05.21946.21946.3 1.76E-07 15/60 R.IINEPTAAAIAYGLDR[166.11].T "sp|P0DMV8|HS71A_HUMAN,sp|P0DMV9|HS71B_HUMAN,sp|P17066|HSP76_HUMAN,tr|A0A0G2JIW1|A0A0G2JIW1_HUMAN" 4 1696.9024 0.16 72246 21946 3 1696.901226 566.6414 Heat shock 70 kDa protein 1A OS=Homo sapiens OX=9606 GN=HSPA1A PE=1 SV=1 4.37 3558.7 - 251277 - - - -0.6653 - 2.659 0.508 - 256.2 1 2 0 -0.0011 16 0 0 0 1.51E+06 9.67E+06 - - - 6.7127 1 221125_WJC_METTL3_EV_vs_WT_F05.21952.21952.3 1.59E-07 14/56 R.GPSLNPVLDYDHGSR.S "sp|P43243|MATR3_HUMAN,tr|A8MXP9|A8MXP9_HUMAN,tr|D6R991|D6R991_HUMAN,tr|A0A0R4J2E8|A0A0R4J2E8_HUMAN,tr|D6REM6|D6REM6_HUMAN" 5 1625.7798 1.32 72250 21952 3 1625.778012 542.9339 Matrin-3 OS=Homo sapiens OX=9606 GN=MATR3 PE=1 SV=2 5.21 3559.5 - 262673 - - - -1.0899 - 3.013 0.667 - 329.3 1 2 0 -0.0018 15 0 0 0 7.94E+06 6.02E+06 - - - 8.8539 1 221125_WJC_METTL3_EV_vs_WT_F05.21961.21961.2 3.77E-08 30-Oct K.SYELPDGQVITIGNER.F "sp|Q6S8J3|POTEE_HUMAN,sp|P63261|ACTG_HUMAN,sp|P68133|ACTS_HUMAN,sp|P62736|ACTA_HUMAN,sp|Q9BYX7|ACTBM_HUMAN,sp|P68032|ACTC_HUMAN,sp|Q562R1|ACTBL_HUMAN,sp|P60709|ACTB_HUMAN,sp|P63267|ACTH_HUMAN,sp|A5A3E0|POTEF_HUMAN,tr|A0A804GS07|A0A804GS07_HUMAN,tr|E7EVS6|E7EVS6_HUMAN,tr|A0A6Q8PFE4|A0A6Q8PFE4_HUMAN,tr|A0A2R8YEA7|A0A2R8YEA7_HUMAN,tr|A0A804HKV3|A0A804HKV3_HUMAN,tr|A0A2R8Y793|A0A2R8Y793_HUMAN,tr|I3L4N8|I3L4N8_HUMAN,tr|A6NL76|A6NL76_HUMAN" 18 1789.8846 1.62 72256 21961 2 1789.87751 895.9496 POTE ankyrin domain family member E OS=Homo sapiens OX=9606 GN=POTEE PE=2 SV=3 4.14 3560.6 - 162069 - - - -3.9852 - 2.303 0.655 - 269.8 1 2 0 -0.0071 16 0 0 0 1.66E+07 1.02E+07 - - - 5.9275 1 221125_WJC_METTL3_EV_vs_WT_F05.21965.21965.3 4.12E-08 15/84 R.DVPEDVAQEMVESGYVC[160.03]EGDHK[136.11].T "sp|Q9H4A3|WNK1_HUMAN,tr|F5GWT4|F5GWT4_HUMAN" 2 2500.0614 1.97 72258 21965 3 2500.06078 834.3611 Serine\threonine-protein kinase WNK1 OS=Homo sapiens OX=9606 GN=WNK1 PE=1 SV=2 3.95 3561.2 - 457221 - - - -0.236 - 2.779 0.675 - 210.8 1 2 0 -0.0006 22 0 0 0 1.83E+07 9.28E+06 - - - 8.4886 0.9985 221125_WJC_METTL3_EV_vs_WT_F05.21972.21972.4 0.000542 11/114 R.HVAEVLEYTK[136.11]DEQLESLFQR[166.11].T "sp|P05198|IF2A_HUMAN,tr|H0YJS4|H0YJS4_HUMAN,tr|G3V4T5|G3V4T5_HUMAN" 3 2451.2401 0.99 72263 21972 4 2451.239227 613.8173 Eukaryotic translation initiation factor 2 subunit 1 OS=Homo sapiens OX=9606 GN=EIF2S1 PE=1 SV=3 4.57 3562.1 - 135005 - - - -0.3459 - 1.816 0.354 - 27.2 1 2 1 -0.0008 20 0 0 0 2.44E+07 2.47E+07 - - - 2.5064 1 221125_WJC_METTL3_EV_vs_WT_F05.21980.21980.2 2.85E-09 14/30 R.IINEPTAAAIAYGLDR[166.11].T "sp|P0DMV8|HS71A_HUMAN,sp|P0DMV9|HS71B_HUMAN,sp|P17066|HSP76_HUMAN,tr|A0A0G2JIW1|A0A0G2JIW1_HUMAN" 4 1696.9024 0.09 72269 21980 2 1696.902001 849.4585 Heat shock 70 kDa protein 1A OS=Homo sapiens OX=9606 GN=HSPA1A PE=1 SV=1 4.37 3563.1 - 390632 - - - -0.2086 - 3.103 0.603 - 528 1 2 0 -0.0004 16 0 0 0 8.82E+05 9.68E+06 - - - 6.2786 0.9999 221125_WJC_METTL3_EV_vs_WT_F05.21984.21984.4 5.33E-10 16/114 R.HVAEVLEYTKDEQLESLFQR.T "sp|P05198|IF2A_HUMAN,tr|H0YJS4|H0YJS4_HUMAN,tr|G3V4T5|G3V4T5_HUMAN" 3 2433.2176 1 72272 21984 4 2433.219976 609.3117 Eukaryotic translation initiation factor 2 subunit 1 OS=Homo sapiens OX=9606 GN=EIF2S1 PE=1 SV=3 4.57 3563.6 - 363295 - - - 0.9744 - 3.386 0.6 - 227.3 1 2 1 0.0024 20 0 0 0 2.48E+07 2.49E+07 - - - 4.8555 1 221125_WJC_METTL3_EV_vs_WT_F05.21990.21990.3 4.71E-07 14/116 R.SPNPEGINIYEPAPPTGPTQRPLETLGNFR.G sp|Q6ZVX7|FBX50_HUMAN 1 3261.6418 999 72276 21990 3 3261.64182 1088.2212 F-box only protein 50 OS=Homo sapiens OX=9606 GN=NCCRP1 PE=1 SV=1 4.78 3564.4 - 490854 - - - -0.0064 - 2.877 0.55 - 104.7 1 2 0 0 30 0 0 0 9.45E+06 0.00E+00 - - - 7.1031 1 221125_WJC_METTL3_EV_vs_WT_F05.21993.21993.3 1.08E-08 13/108 R.DLGNPNTAPPTPELHGINPVFLSSNPSR.W "sp|P78364|PHC1_HUMAN,tr|J3KQH6|J3KQH6_HUMAN" 2 2940.473 4.04 72279 21993 3 2940.478821 981.1649 Polyhomeotic-like protein 1 OS=Homo sapiens OX=9606 GN=PHC1 PE=1 SV=3 5.32 3564.7 - 233531 - - - 1.9851 - 2.537 0.615 - 78.5 1 2 0 0.0058 28 0 0 0 1.29E+07 3.18E+06 - - - 7.5369 0.9994 221125_WJC_METTL3_EV_vs_WT_F05.22007.22007.3 1.10E-06 15/76 K.SSATSGDIWPGLSAYDNSPR.S "sp|Q9NYF8|BCLF1_HUMAN,tr|E9PKI6|E9PKI6_HUMAN,tr|A0A1W2PQ43|A0A1W2PQ43_HUMAN,tr|E9PK91|E9PK91_HUMAN,tr|E9PJA7|E9PJA7_HUMAN,tr|E9PK09|E9PK09_HUMAN,tr|E9PQN2|E9PQN2_HUMAN" 7 2079.9498 4.9 72287 22007 3 2080.954405 694.3239 Bcl-2-associated transcription factor 1 OS=Homo sapiens OX=9606 GN=BCLAF1 PE=1 SV=2 4.21 3566.6 - 303455 - - - 483.0131 - 2.705 0.56 - 267 1 2 0 1.0046 20 0 0 0 1.79E+07 3.66E+06 - - - 6.9193 0.9931 221125_WJC_METTL3_EV_vs_WT_F05.22008.22008.3 0.0232 Dec-96 R.QTASVTLQAIAAQNAAVQAVNAHSN.L "sp|Q16891|MIC60_HUMAN,tr|B9A067|B9A067_HUMAN,tr|C9J406|C9J406_HUMAN,tr|H7C463|H7C463_HUMAN" 4 2477.2623 - 72288 22008 3 2477.262997 826.7614 MICOS complex subunit MIC60 OS=Homo sapiens OX=9606 GN=IMMT PE=1 SV=1 6.74 3566.8 - 273411 - - - 0.2963 - 2.892 0.414 - 97.7 1 1 0 0.0007 25 0 0 0 - - - - - 5.5986 1 221125_WJC_METTL3_EV_vs_WT_F05.22011.22011.2 2.83E-09 30-Dec K.SYELPDGQVITIGNER[166.11].F "sp|Q6S8J3|POTEE_HUMAN,sp|P63261|ACTG_HUMAN,sp|P68133|ACTS_HUMAN,sp|P62736|ACTA_HUMAN,sp|Q9BYX7|ACTBM_HUMAN,sp|P68032|ACTC_HUMAN,sp|Q562R1|ACTBL_HUMAN,sp|P60709|ACTB_HUMAN,sp|P63267|ACTH_HUMAN,sp|A5A3E0|POTEF_HUMAN,tr|A0A804GS07|A0A804GS07_HUMAN,tr|E7EVS6|E7EVS6_HUMAN,tr|A0A6Q8PFE4|A0A6Q8PFE4_HUMAN,tr|A0A2R8YEA7|A0A2R8YEA7_HUMAN,tr|A0A804HKV3|A0A804HKV3_HUMAN,tr|A0A2R8Y793|A0A2R8Y793_HUMAN,tr|I3L4N8|I3L4N8_HUMAN,tr|A6NL76|A6NL76_HUMAN" 18 1799.8929 1.62 72291 22011 2 1799.89376 900.9537 POTE ankyrin domain family member E OS=Homo sapiens OX=9606 GN=POTEE PE=2 SV=3 4.14 3567.1 - 277238 - - - 0.4706 - 2.5 0.696 - 430.5 1 2 0 0.0008 16 0 0 0 1.66E+07 1.02E+07 - - - 6.4341 0.999 221125_WJC_METTL3_EV_vs_WT_F05.22014.22014.3 0.000178 Aug-60 K.SYELPDGQVITIGNER.F "sp|Q6S8J3|POTEE_HUMAN,sp|P63261|ACTG_HUMAN,sp|P68133|ACTS_HUMAN,sp|P62736|ACTA_HUMAN,sp|Q9BYX7|ACTBM_HUMAN,sp|P68032|ACTC_HUMAN,sp|Q562R1|ACTBL_HUMAN,sp|P60709|ACTB_HUMAN,sp|P63267|ACTH_HUMAN,sp|A5A3E0|POTEF_HUMAN,tr|A0A804GS07|A0A804GS07_HUMAN,tr|E7EVS6|E7EVS6_HUMAN,tr|A0A6Q8PFE4|A0A6Q8PFE4_HUMAN,tr|A0A2R8YEA7|A0A2R8YEA7_HUMAN,tr|A0A804HKV3|A0A804HKV3_HUMAN,tr|A0A2R8Y793|A0A2R8Y793_HUMAN,tr|I3L4N8|I3L4N8_HUMAN,tr|A6NL76|A6NL76_HUMAN" 18 1789.8846 0.14 72292 22014 3 1789.89141 597.6355 POTE ankyrin domain family member E OS=Homo sapiens OX=9606 GN=POTEE PE=2 SV=3 4.14 3567.6 - 244163 - - - 3.7807 - 1.887 0.422 - 77.5 1 2 0 0.0068 16 0 0 0 8.10E+06 5.78E+07 - - - 4.8723 0.9479 221125_WJC_METTL3_EV_vs_WT_F05.22015.22015.3 0.0277 Aug-60 R.R[166.11]AEQDSTTVAAFASSL.V "sp|Q86U44|MTA70_HUMAN,tr|F5H6D8|F5H6D8_HUMAN,tr|H0YFV6|H0YFV6_HUMAN,tr|B4DTN4|B4DTN4_HUMAN" 4 1662.8088 0.22 72293 22015 3 1662.809003 555.2769 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 4.37 3567.7 - 206232 - - - 0.0926 - 1.584 0.365 - 56.2 1 1 0 0.0002 16 0 0 0 7.02E+05 3.16E+06 - - - 3.7895 0.9992 221125_WJC_METTL3_EV_vs_WT_F05.22018.22018.3 0.0042 10/100 R.TTPSATSLPQTVVMTSPVTLTSQTTK.T sp|P18846|ATF1_HUMAN 1 2676.3892 0.53 72296 22018 3 2676.392755 893.137 Cyclic AMP-dependent transcription factor ATF-1 OS=Homo sapiens OX=9606 GN=ATF1 PE=1 SV=2 8.41 3568.1 - 200822 - - - 1.3421 - 1.93 0.328 - 65.7 1 2 0 0.0036 26 0 0 0 3.42E+06 6.39E+06 - - - 3.7086 1 221125_WJC_METTL3_EV_vs_WT_F05.22022.22022.3 2.19E-14 19/92 R.NGPGFHNDIDSNSTIQEILIPASK[136.11].V sp|Q96I24|FUBP3_HUMAN 1 2574.2805 2.13 72298 22022 3 2574.280077 859.1008 Far upstream element-binding protein 3 OS=Homo sapiens OX=9606 GN=FUBP3 PE=1 SV=2 4.54 3568.6 - 780282 - - - -0.1822 - 3.926 0.757 - 181.2 1 2 0 -0.0005 24 0 0 0 7.52E+07 3.53E+07 - - - 10.1561 1 221125_WJC_METTL3_EV_vs_WT_F05.22024.22024.2 3.22E-06 30-Dec R.R[166.11]AEQDSTTVAAFASSL.V "sp|Q86U44|MTA70_HUMAN,tr|F5H6D8|F5H6D8_HUMAN,tr|H0YFV6|H0YFV6_HUMAN,tr|B4DTN4|B4DTN4_HUMAN" 4 1662.8088 0.01 72300 22024 2 1662.808402 832.4117 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 4.37 3568.8 - 3.37E+06 - - - -0.2688 - 2.519 0.625 - 294.4 1 1 0 -0.0004 16 0 0 0 5.17E+05 8.48E+07 - - - 5.9285 0.9565 221125_WJC_METTL3_EV_vs_WT_F05.22027.22027.4 0.582 May-84 R.IYSEVTC[160.03]FFDHVTHR.V sp|Q16706|MA2A1_HUMAN 1 1909.8781 0.8 72303 22027 4 1909.877041 478.4768 Alpha-mannosidase 2 OS=Homo sapiens OX=9606 GN=MAN2A1 PE=1 SV=2 5.99 3569.2 - 115223 - - - -0.5639 - 0.942 0.168 - 17.5 1 2 0 -0.0011 15 0 0 0 5.02E+05 6.29E+05 - - - 0.6666 0.9997 221125_WJC_METTL3_EV_vs_WT_F05.22040.22040.4 0.000721 9/108 R.VIHLSNLPHSGYSDSAVLK[136.11].L "sp|P43243|MATR3_HUMAN,tr|B3KM87|B3KM87_HUMAN,tr|A8MXP9|A8MXP9_HUMAN,tr|D6RBK5|D6RBK5_HUMAN,tr|A0A0R4J2E8|A0A0R4J2E8_HUMAN,tr|H0Y8T4|H0Y8T4_HUMAN,tr|D6REM6|D6REM6_HUMAN" 7 2044.0833 1.81 72312 22040 4 2044.087996 512.0281 Matrin-3 OS=Homo sapiens OX=9606 GN=MATR3 PE=1 SV=2 6.89 3571 - 139064 - - - 2.3023 - 2.064 0.407 - 80.2 1 2 0 0.0047 19 0 0 0 2.38E+06 1.31E+06 - - - 3.0124 1 221125_WJC_METTL3_EV_vs_WT_F05.22048.22048.3 0.00043 14/96 K.VQETGDIVISNAYVDLAPTSGTSAK.T "sp|P51659|DHB4_HUMAN,tr|A0A2R8Y7L2|A0A2R8Y7L2_HUMAN,tr|A0A2R8YD50|A0A2R8YD50_HUMAN,tr|A0A804HIR1|A0A804HIR1_HUMAN,tr|E7ET17|E7ET17_HUMAN,tr|E7EPL9|E7EPL9_HUMAN,tr|A0A804HKU2|A0A804HKU2_HUMAN,tr|A0A804HK65|A0A804HK65_HUMAN" 8 2535.2704 0.38 72318 22048 3 2535.276758 846.0974 Peroxisomal multifunctional enzyme type 2 OS=Homo sapiens OX=9606 GN=HSD17B4 PE=1 SV=3 4.03 3571.9 - 171219 - - - 2.4968 - 3.248 0.538 - 132.4 1 2 0 0.0063 25 0 0 0 3.42E+06 8.93E+06 - - - 7.2467 1 221125_WJC_METTL3_EV_vs_WT_F05.22051.22051.3 3.44E-09 20/60 R.HGVQELEIELQSQLSK.K "sp|P35527|K1C9_HUMAN,tr|K7EQQ3|K7EQQ3_HUMAN" 2 1836.9581 3611.21 72319 22051 3 1836.957805 613.3267 "Keratin, type I cytoskeletal 9 OS=Homo sapiens OX=9606 GN=KRT9 PE=1 SV=3" 4.75 3572.3 - 1.63E+06 - - - -0.1835 - 3.109 0.551 - 258.6 1 2 0 -0.0003 16 0 0 0 5.83E+08 1.62E+05 - - - 7.5935 1 221125_WJC_METTL3_EV_vs_WT_F05.22053.22053.3 3.43E-08 21/84 R.AQTEGINISEEALNHLGEIGTK[136.11].T "sp|Q9Y265|RUVB1_HUMAN,tr|H7C4G5|H7C4G5_HUMAN,tr|J3QLR1|J3QLR1_HUMAN" 3 2331.1798 0.66 72321 22053 3 2331.178779 778.0672 RuvB-like 1 OS=Homo sapiens OX=9606 GN=RUVBL1 PE=1 SV=1 4.48 3572.6 - 688452 - - - -0.4247 - 4.269 0.665 - 486.2 1 2 0 -0.001 22 0 0 0 3.87E+07 5.83E+07 - - - 9.3948 1 221125_WJC_METTL3_EV_vs_WT_F05.22063.22063.3 1.01E-06 17/84 R.EPPRPEPPPPFPPLPLQPPPPR.E sp|Q6ZU65|UBN2_HUMAN 1 2448.3318 2.61 72326 22063 3 2448.336042 817.1179 Ubinuclein-2 OS=Homo sapiens OX=9606 GN=UBN2 PE=1 SV=2 6.24 3574 - 358779 - - - 1.7379 - 2.883 0.609 - 221.7 1 2 0 0.0043 22 0 0 0 1.43E+07 5.47E+06 - - - 7.8389 1 221125_WJC_METTL3_EV_vs_WT_F05.22064.22064.3 6.11E-12 17/84 R.AQTEGINISEEALNHLGEIGTK.T "sp|Q9Y265|RUVB1_HUMAN,tr|H7C4G5|H7C4G5_HUMAN,tr|J3QLR1|J3QLR1_HUMAN" 3 2323.1656 0.67 72327 22064 3 2323.158405 775.3958 RuvB-like 1 OS=Homo sapiens OX=9606 GN=RUVBL1 PE=1 SV=1 4.48 3574.1 - 995586 - - - -3.0837 - 4.228 0.661 - 299 1 2 0 -0.0072 22 0 0 0 3.87E+07 5.81E+07 - - - 9.3256 1 221125_WJC_METTL3_EV_vs_WT_F05.22071.22071.2 2.26E-15 19/30 R.HGVQELEIELQSQLSK.K "sp|P35527|K1C9_HUMAN,tr|K7EQQ3|K7EQQ3_HUMAN" 2 1836.9581 999 72331 22071 2 1836.955212 919.4863 "Keratin, type I cytoskeletal 9 OS=Homo sapiens OX=9606 GN=KRT9 PE=1 SV=3" 4.75 3575 - 235077 - - - -1.595 - 4.514 0.702 - 1227.7 1 2 0 -0.0029 16 0 0 0 2.83E+07 0.00E+00 - - - 7.9305 1 221125_WJC_METTL3_EV_vs_WT_F05.22072.22072.4 9.28E-10 31/174 R.RLEASDGGLDSAELAAELGMEHQAVVGAVK.S "sp|Q9Y285|SYFA_HUMAN,tr|K7ER16|K7ER16_HUMAN,tr|K7EPH2|K7EPH2_HUMAN,tr|K7ER00|K7ER00_HUMAN,tr|K7EK06|K7EK06_HUMAN" 5 3022.503 1.99 72332 22072 4 3022.501228 756.633 Phenylalanine--tRNA ligase alpha subunit OS=Homo sapiens OX=9606 GN=FARSA PE=1 SV=3 4.35 3575.1 - 545071 - - - -0.5744 - 5.212 0.703 - 590 1 2 0 -0.0017 30 0 0 0 9.84E+06 4.94E+06 - - - 5.8496 0.9997 221125_WJC_METTL3_EV_vs_WT_F05.22087.22087.3 8.23E-08 Nov-84 R.TVYGGGC[160.03]SEMLMAHAVTQLANR[166.11].T "sp|P78371|TCPB_HUMAN,tr|F5GWF6|F5GWF6_HUMAN" 2 2375.106 0.66 72341 22087 3 2375.094879 792.7093 T-complex protein 1 subunit beta OS=Homo sapiens OX=9606 GN=CCT2 PE=1 SV=4 6.41 3577.1 - 289061 - - - -4.6722 - 2.326 0.584 - 64.6 1 2 0 -0.0111 22 0 0 0 2.59E+06 3.91E+06 - - - 7.0493 1 221125_WJC_METTL3_EV_vs_WT_F05.22093.22093.3 6.17E-07 15/76 R.SASSTSSLFSSSSQLFPPSR[166.11].L "sp|Q8TB72|PUM2_HUMAN,tr|A0A0C4DG68|A0A0C4DG68_HUMAN" 2 2068.9941 1.25 72343 22093 3 2068.994997 690.672 Pumilio homolog 2 OS=Homo sapiens OX=9606 GN=PUM2 PE=1 SV=2 9.47 3578 - 623991 - - - 0.4413 - 3.306 0.598 - 150.8 1 2 0 0.0009 20 0 0 0 4.90E+07 3.93E+07 - - - 8.1077 0.9319 221125_WJC_METTL3_EV_vs_WT_F05.22094.22094.2 0.756 Jun-34 R.GSAAALC[160.03]NNLSVLQLPAR.N sp|Q9H977|WDR54_HUMAN 1 1853.9782 999 72344 22094 2 1853.981806 927.9964 WD repeat-containing protein 54 OS=Homo sapiens OX=9606 GN=WDR54 PE=1 SV=1 8.25 3578.1 - 340595 - - - 1.9633 - 1.453 0.03 - 57.8 5 2 0 0.0036 18 0 0 0 1.11E+07 0.00E+00 - - - -0.1322 1 221125_WJC_METTL3_EV_vs_WT_F05.22098.22098.3 6.98E-09 18/76 R.SASSTSSLFSSSSQLFPPSR.L "sp|Q8TB72|PUM2_HUMAN,tr|A0A0C4DG68|A0A0C4DG68_HUMAN" 2 2058.9858 1.25 72346 22098 3 2058.984675 687.3359 Pumilio homolog 2 OS=Homo sapiens OX=9606 GN=PUM2 PE=1 SV=2 9.47 3578.6 - 1.22E+06 - - - -0.5532 - 3.145 0.598 - 257.4 1 2 0 -0.0011 20 0 0 0 5.07E+07 4.05E+07 - - - 7.9866 1 221125_WJC_METTL3_EV_vs_WT_F05.22110.22110.2 7.62E-07 Dec-38 R.SASSTSSLFSSSSQLFPPSR[166.11].L "sp|Q8TB72|PUM2_HUMAN,tr|A0A0C4DG68|A0A0C4DG68_HUMAN" 2 2068.9941 1.36 72353 22110 2 2068.989665 1035.5043 Pumilio homolog 2 OS=Homo sapiens OX=9606 GN=PUM2 PE=1 SV=2 9.47 3580 - 559504 - - - -2.1358 - 2.868 0.641 - 180.9 1 2 0 -0.0044 20 0 0 0 1.81E+07 1.33E+07 - - - 6.3644 1 221125_WJC_METTL3_EV_vs_WT_F05.22111.22111.2 1.92E-12 20/38 R.SASSTSSLFSSSSQLFPPSR.L "sp|Q8TB72|PUM2_HUMAN,tr|A0A0C4DG68|A0A0C4DG68_HUMAN" 2 2058.9858 1.36 72354 22111 2 2058.981816 1030.5002 Pumilio homolog 2 OS=Homo sapiens OX=9606 GN=PUM2 PE=1 SV=2 9.47 3580.2 - 385123 - - - -1.9417 - 3.828 0.737 - 613.9 1 2 0 -0.004 20 0 0 0 1.82E+07 1.33E+07 - - - 7.7834 0.9965 221125_WJC_METTL3_EV_vs_WT_F05.22120.22120.3 3.61E-05 15/64 K.DQLIYNLLK[136.11]EEQTPQNK[136.11].L "sp|P00338|LDHA_HUMAN,tr|F5GXU1|F5GXU1_HUMAN,tr|F5GXC7|F5GXC7_HUMAN,tr|F5H8H6|F5H8H6_HUMAN,tr|F5GZQ4|F5GZQ4_HUMAN,tr|F5GXH2|F5GXH2_HUMAN,tr|F5GYU2|F5GYU2_HUMAN,tr|F5H5J4|F5H5J4_HUMAN,tr|F5H6W8|F5H6W8_HUMAN,tr|F5GXY2|F5GXY2_HUMAN,tr|F5GWW2|F5GWW2_HUMAN" 11 2089.1026 1.08 72359 22120 3 2089.112707 697.3748 L-lactate dehydrogenase A chain OS=Homo sapiens OX=9606 GN=LDHA PE=1 SV=2 4.68 3581.3 - 735736 - - - 4.8212 - 2.727 0.43 - 212.3 1 2 1 0.0101 17 0 0 0 9.19E+06 8.48E+06 - - - 5.8657 1 221125_WJC_METTL3_EV_vs_WT_F05.22121.22121.3 1.39E-10 23/72 R.HYSLSLTAEQLSHSVAELR.S "sp|Q14687|GSE1_HUMAN,tr|H0Y613|H0Y613_HUMAN" 2 2140.0913 1.51 72360 22121 3 2140.085985 714.371 Genetic suppressor element 1 OS=Homo sapiens OX=9606 GN=GSE1 PE=1 SV=3 6 3581.4 - 424513 - - - -2.4751 - 3.871 0.656 - 736 1 2 0 -0.0053 19 0 0 0 6.86E+06 4.54E+06 - - - 9.1776 0.9872 221125_WJC_METTL3_EV_vs_WT_F05.22122.22122.3 7.33E-06 Dec-68 K.R[166.11]R[166.11]AEQDSTTVAAFASSLV.S "sp|Q86U44|MTA70_HUMAN,tr|F5H6D8|F5H6D8_HUMAN,tr|H0YFV6|H0YFV6_HUMAN,tr|B4DTN4|B4DTN4_HUMAN" 4 1927.9866 0.01 72361 22122 3 1927.985066 643.6695 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 6.07 3581.5 - 555717 - - - -0.8185 - 2.327 0.539 - 129 1 1 1 -0.0016 18 0 0 0 9.05E+04 1.05E+07 - - - 6.652 0.9434 221125_WJC_METTL3_EV_vs_WT_F05.22123.22123.3 5.30E-07 13/76 K.GNPQGFNQGLDC[160.03]DVIVAEVR[166.11].S sp|Q86U44|MTA70_HUMAN 1 2197.0461 0.03 72362 22123 3 2198.030844 733.356 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 4.03 3581.7 - 355057 - - - 448.1963 - 2.537 0.614 - 191.9 1 2 0 0.9847 20 0 0 0 1.00E+05 3.19E+06 - - - 7.3713 1 221125_WJC_METTL3_EV_vs_WT_F05.22131.22131.3 2.56E-08 Dec-72 R.HYSLSLTAEQLSHSVAELR[166.11].S "sp|Q14687|GSE1_HUMAN,tr|H0Y613|H0Y613_HUMAN" 2 2150.0996 1.5 72366 22131 3 2150.096179 717.7071 Genetic suppressor element 1 OS=Homo sapiens OX=9606 GN=GSE1 PE=1 SV=3 6 3582.7 - 166569 - - - -1.5688 - 2.627 0.594 - 158.3 1 2 0 -0.0034 19 0 0 0 6.97E+06 4.63E+06 - - - 7.5345 0.9016 221125_WJC_METTL3_EV_vs_WT_F05.22132.22132.3 0.0016 Dec-96 K.IDSIPHLNNSTPLVDPSVYGYGVQK.R sp|Q96I24|FUBP3_HUMAN 1 2712.3759 -1 72367 22132 3 2713.360924 905.1326 Far upstream element-binding protein 3 OS=Homo sapiens OX=9606 GN=FUBP3 PE=1 SV=2 5.21 3582.9 - 314587 - - - 363.1606 - 2.274 0.484 - 121.2 1 2 0 0.985 25 0 0 0 0.00E+00 0.00E+00 - - - 5.5533 1 221125_WJC_METTL3_EV_vs_WT_F05.22135.22135.2 2.82E-10 Oct-32 K.DGLNDDDFEPYLSPQAR.P "sp|Q9Y5A9|YTHD2_HUMAN,tr|S4R3J8|S4R3J8_HUMAN" 2 1950.8595 2.08 72370 22135 2 1950.858142 976.4371 YTH domain-containing family protein 2 OS=Homo sapiens OX=9606 GN=YTHDF2 PE=1 SV=2 3.71 3583.2 - 155044 - - - -0.7217 - 2.422 0.74 - 187.7 1 1 0 -0.0014 17 0 0 0 2.06E+06 9.91E+05 - - - 6.681 0.9999 221125_WJC_METTL3_EV_vs_WT_F05.22138.22138.3 2.07E-07 18/68 R.TSQNSELNNMQDLVEDYK.K sp|P35908|K22E_HUMAN 1 2126.9426 2377.49 72371 22138 3 2126.950911 709.9882 "Keratin, type II cytoskeletal 2 epidermal OS=Homo sapiens OX=9606 GN=KRT2 PE=1 SV=2" 3.92 3583.7 - 629035 - - - 3.8943 - 3.183 0.631 - 404.4 1 2 0 0.0083 18 0 0 0 6.09E+07 2.56E+04 - - - 8.4558 1 221125_WJC_METTL3_EV_vs_WT_F05.22140.22140.3 9.55E-09 14/128 K.QYPANQGQEVEYFVAGTHPYPPGPGVALTADTK.L "sp|O43660|PLRG1_HUMAN,tr|D6RA26|D6RA26_HUMAN" 2 3501.6841 1.61 72373 22140 3 3501.694506 1168.2353 Pleiotropic regulator 1 OS=Homo sapiens OX=9606 GN=PLRG1 PE=1 SV=1 4.65 3583.9 - 173919 - - - 2.9717 - 2.646 0.687 - 105.2 1 2 0 0.0104 33 0 0 0 2.35E+06 1.45E+06 - - - 8.4351 1 221125_WJC_METTL3_EV_vs_WT_F05.22141.22141.2 1.58E-06 17/34 R.TSQNSELNNMQDLVEDYK.K sp|P35908|K22E_HUMAN 1 2126.9426 999 72374 22141 2 2126.952691 1064.4786 "Keratin, type II cytoskeletal 2 epidermal OS=Homo sapiens OX=9606 GN=KRT2 PE=1 SV=2" 3.92 3584.1 - 172889 - - - 4.7312 - 3.524 0.659 - 882.2 1 2 0 0.0101 18 0 0 0 2.98E+07 0.00E+00 - - - 7.002 1 221125_WJC_METTL3_EV_vs_WT_F05.22144.22144.2 4.49E-10 Aug-32 K.DGLNDDDFEPYLSPQAR[166.11].P "sp|Q9Y5A9|YTHD2_HUMAN,tr|S4R3J8|S4R3J8_HUMAN" 2 1960.8678 2.22 72377 22144 2 1960.864636 981.4412 YTH domain-containing family protein 2 OS=Homo sapiens OX=9606 GN=YTHDF2 PE=1 SV=2 3.71 3584.5 - 130156 - - - -1.6238 - 1.814 0.727 - 125.4 1 1 0 -0.0032 17 0 0 0 2.06E+06 9.30E+05 - - - 5.8738 0.9714 221125_WJC_METTL3_EV_vs_WT_F05.22145.22145.4 0.262 6/102 K.LIKEIKNYIQGINLVQAK.K "sp|P52815|RM12_HUMAN,tr|B4DLN1|B4DLN1_HUMAN" 2 2084.2358 3.83 72378 22145 4 2084.239287 522.0662 "39S ribosomal protein L12, mitochondrial OS=Homo sapiens OX=9606 GN=MRPL12 PE=1 SV=2" 9.53 3584.6 - 119566 - - - 1.6917 - 1.349 0.235 - 25.9 1 2 2 0.0035 18 0 0 0 1.39E+06 3.63E+05 - - - 1.373 0.9993 221125_WJC_METTL3_EV_vs_WT_F05.22147.22147.3 0.00098 Sep-84 R.EPPR[166.11]PEPPPPFPPLPLQPPPPR[166.11].E sp|Q6ZU65|UBN2_HUMAN 1 2468.3483 2.73 72380 22147 3 2468.3429 823.7901 Ubinuclein-2 OS=Homo sapiens OX=9606 GN=UBN2 PE=1 SV=2 6.24 3584.9 - 114421 - - - -2.1986 - 1.634 0.4 - 47.6 1 2 0 -0.0054 22 0 0 0 2.11E+07 7.73E+06 - - - 4.1623 0.8827 221125_WJC_METTL3_EV_vs_WT_F05.22151.22151.3 0.000263 Dec-84 K.DSGPLPTPPGVSLLGEPPKDYR.L "tr|E9PAU2|E9PAU2_HUMAN,tr|A0A087WZ13|A0A087WZ13_HUMAN" 2 2291.1798 0.99 72383 22151 3 2291.198876 764.7339 Ribonucleoprotein PTB-binding 1 OS=Homo sapiens OX=9606 GN=RAVER1 PE=1 SV=1 4.56 3585.5 - 448144 - - - 8.3424 - 2.001 0.364 - 80.4 1 2 1 0.0191 22 0 0 0 6.39E+08 6.48E+08 - - - 4.2375 0.9994 221125_WJC_METTL3_EV_vs_WT_F05.22152.22152.3 5.95E-05 Dec-84 K.DSGPLPTPPGVSLLGEPPK[136.11]DYR[166.11].L "tr|E9PAU2|E9PAU2_HUMAN,tr|A0A087WZ13|A0A087WZ13_HUMAN" 2 2309.2022 0.98 72384 22152 3 2309.206043 770.7414 Ribonucleoprotein PTB-binding 1 OS=Homo sapiens OX=9606 GN=RAVER1 PE=1 SV=1 4.56 3585.6 - 309360 - - - 1.6504 - 2.236 0.443 - 85.7 1 2 1 0.0038 22 0 0 0 6.40E+08 6.52E+08 - - - 5.3857 0.9998 221125_WJC_METTL3_EV_vs_WT_F05.22154.22154.3 2.54E-05 15/68 K.LIKEIKNYIQGINLVQAK.K "sp|P52815|RM12_HUMAN,tr|B4DLN1|B4DLN1_HUMAN" 2 2084.2358 4.18 72386 22154 3 2084.242132 695.7525 "39S ribosomal protein L12, mitochondrial OS=Homo sapiens OX=9606 GN=MRPL12 PE=1 SV=2" 9.53 3585.9 - 255578 - - - 3.0568 - 2.818 0.602 - 218.1 1 2 2 0.0064 18 0 0 0 5.35E+06 1.28E+06 - - - 7.8298 0.9999 221125_WJC_METTL3_EV_vs_WT_F05.22155.22155.4 3.62E-07 11/120 K.YR[166.11]PQTLNDLISHQDILSTIQK[136.11].F "sp|P40937|RFC5_HUMAN,tr|F5H0U6|F5H0U6_HUMAN,tr|C9JH72|C9JH72_HUMAN,tr|F5H304|F5H304_HUMAN" 4 2500.3405 0.87 72387 22155 4 2500.350314 626.0924 Replication factor C subunit 5 OS=Homo sapiens OX=9606 GN=RFC5 PE=1 SV=1 6.75 3586 - 213962 - - - 3.9423 - 2.364 0.552 - 72.6 1 2 0 0.0099 21 0 0 0 8.69E+05 9.99E+05 - - - 4.3123 1 221125_WJC_METTL3_EV_vs_WT_F05.22156.22156.3 3.84E-14 16/76 R.GRDDC[160.03]GTFEDTGPLLQFDYK.A sp|Q14684|RRP1B_HUMAN 1 2333.027 0.09 72388 22156 3 2333.032228 778.683 Ribosomal RNA processing protein 1 homolog B OS=Homo sapiens OX=9606 GN=RRP1B PE=1 SV=3 4.04 3586.1 - 186573 - - - 2.2293 - 3.419 0.747 - 395.3 1 2 1 0.0052 20 0 0 0 4.20E+06 4.82E+07 - - - 9.8493 0.9998 221125_WJC_METTL3_EV_vs_WT_F05.22157.22157.2 5.41E-08 Oct-34 K.SSGPTSLFAVTVAPPGAR[166.11].Q "sp|Q00839|HNRPU_HUMAN,tr|A0A1W2PP35|A0A1W2PP35_HUMAN,tr|A0A1W2PPS1|A0A1W2PPS1_HUMAN,tr|A0A1W2PP22|A0A1W2PP22_HUMAN,tr|A0A1X7SBS1|A0A1X7SBS1_HUMAN" 5 1723.9133 1.04 72389 22157 2 1723.916282 862.9639 Heterogeneous nuclear ribonucleoprotein U OS=Homo sapiens OX=9606 GN=HNRNPU PE=1 SV=6 9.47 3586.3 - 183628 - - - 1.7565 - 2.407 0.61 - 268.4 1 2 0 0.003 18 0 0 0 2.52E+07 2.43E+07 - - - 5.705 1 221125_WJC_METTL3_EV_vs_WT_F05.22158.22158.3 4.09E-08 10/128 K.QYPANQGQEVEYFVAGTHPYPPGPGVALTADTK[136.11].L "sp|O43660|PLRG1_HUMAN,tr|D6RA26|D6RA26_HUMAN" 2 3509.6983 1.61 72390 22158 3 3509.70137 1170.9067 Pleiotropic regulator 1 OS=Homo sapiens OX=9606 GN=PLRG1 PE=1 SV=1 4.65 3586.4 - 169798 - - - 0.8747 - 2.087 0.591 - 42.2 1 2 0 0.0031 33 0 0 0 2.35E+06 1.45E+06 - - - 6.8209 0.9999 221125_WJC_METTL3_EV_vs_WT_F05.22159.22159.3 4.11E-05 Oct-64 K.YHESSQMSSLVETFVSK[136.11].A "sp|Q7Z478|DHX29_HUMAN,tr|A0A087WYN9|A0A087WYN9_HUMAN" 2 1965.9233 0.05 72391 22159 3 1965.929607 656.3151 ATP-dependent RNA helicase DHX29 OS=Homo sapiens OX=9606 GN=DHX29 PE=1 SV=2 5.4 3586.5 - 157655 - - - 3.1863 - 2.244 0.575 - 102.6 1 2 0 0.0063 17 0 0 0 8.63E+04 1.66E+06 - - - 6.9909 0.9812 221125_WJC_METTL3_EV_vs_WT_F05.22161.22161.2 4.5 14-Jun K.LSEFELIK.M "sp|Q9BXT8|RNF17_HUMAN,tr|Q5T6R1|Q5T6R1_HUMAN,tr|Q5T2J8|Q5T2J8_HUMAN" 3 977.5433 73.26 72393 22161 2 977.543716 489.779 RING finger protein 17 OS=Homo sapiens OX=9606 GN=RNF17 PE=1 SV=3 4.53 3586.8 - 120623 - - - 0.3765 - 1.344 0.041 - 76.3 1 2 0 0.0004 8 0 0 0 1.56E+06 2.12E+04 - - - 0.2354 0.9998 221125_WJC_METTL3_EV_vs_WT_F05.22162.22162.3 2.89E-06 Oct-80 R.YQADIPEMLLEGESDEREQSK.L "sp|Q9BTC8|MTA3_HUMAN,tr|E9PCS8|E9PCS8_HUMAN,tr|E7EQY4|E7EQY4_HUMAN,tr|E7EV10|E7EV10_HUMAN,tr|F6RRE2|F6RRE2_HUMAN" 5 2466.122 0.65 72394 22162 3 2466.121192 823.048 Metastasis-associated protein MTA3 OS=Homo sapiens OX=9606 GN=MTA3 PE=1 SV=2 4 3586.9 - 103394 - - - -0.3475 - 2.042 0.5 - 82.4 1 2 1 -0.0009 21 0 0 0 5.54E+05 8.59E+05 - - - 5.8259 0.9989 221125_WJC_METTL3_EV_vs_WT_F05.22164.22164.3 0.00461 Jun-80 R.YQADIPEMLLEGESDER[166.11]EQSK[136.11].L "sp|Q9BTC8|MTA3_HUMAN,tr|E9PCS8|E9PCS8_HUMAN,tr|E7EQY4|E7EQY4_HUMAN,tr|E7EV10|E7EV10_HUMAN,tr|F6RRE2|F6RRE2_HUMAN" 5 2484.1445 0.65 72396 22164 3 2484.151564 829.0554 Metastasis-associated protein MTA3 OS=Homo sapiens OX=9606 GN=MTA3 PE=1 SV=2 4 3587.2 - 85606.3 - - - 2.836 - 1.622 0.526 - 33 1 2 1 0.007 21 0 0 0 5.54E+05 8.59E+05 - - - 5.562 0.9995 221125_WJC_METTL3_EV_vs_WT_F05.22168.22168.3 7.18E-08 22/68 K.LVINGNPITIFQERDPSK.L sp|P04406|G3P_HUMAN 1 2040.1004 1.06 72398 22168 3 2040.108996 681.0407 Glyceraldehyde-3-phosphate dehydrogenase OS=Homo sapiens OX=9606 GN=GAPDH PE=1 SV=3 6.07 3587.7 - 2.55E+06 - - - 4.2184 - 3.321 0.58 - 556.5 1 2 1 0.0086 18 0 0 0 9.22E+07 8.69E+07 - - - 7.9928 0.9998 221125_WJC_METTL3_EV_vs_WT_F05.22169.22169.3 4.83E-08 20/68 K.LVINGNPITIFQER[166.11]DPSK[136.11].L sp|P04406|G3P_HUMAN 1 2058.1229 1.06 72399 22169 3 2058.128648 687.0482 Glyceraldehyde-3-phosphate dehydrogenase OS=Homo sapiens OX=9606 GN=GAPDH PE=1 SV=3 6.07 3587.8 - 2.59E+06 - - - 2.8123 - 3.217 0.547 - 409.9 1 2 1 0.0058 18 0 0 0 9.22E+07 8.69E+07 - - - 7.5465 1 221125_WJC_METTL3_EV_vs_WT_F05.22170.22170.2 2.47E-08 Dec-34 K.SSGPTSLFAVTVAPPGAR.Q "sp|Q00839|HNRPU_HUMAN,tr|A0A1W2PP35|A0A1W2PP35_HUMAN,tr|A0A1W2PPS1|A0A1W2PPS1_HUMAN,tr|A0A1W2PP22|A0A1W2PP22_HUMAN,tr|A0A1X7SBS1|A0A1X7SBS1_HUMAN" 5 1713.905 1.04 72400 22170 2 1713.908818 857.9598 Heterogeneous nuclear ribonucleoprotein U OS=Homo sapiens OX=9606 GN=HNRNPU PE=1 SV=6 9.47 3588 - 283417 - - - 2.237 - 2.631 0.631 - 393 1 2 0 0.0038 18 0 0 0 2.52E+07 2.43E+07 - - - 6.0787 0.9975 221125_WJC_METTL3_EV_vs_WT_F05.22173.22173.3 4.33E-08 Dec-80 C.LAISTPDAPATQDGVESLLQK[136.11].F "sp|Q86U44|MTA70_HUMAN,tr|B4E349|B4E349_HUMAN,tr|F5H6D8|F5H6D8_HUMAN,tr|H0YFV6|H0YFV6_HUMAN,tr|B4DTN4|B4DTN4_HUMAN" 5 2161.1358 0.01 72403 22173 3 2161.13829 721.3859 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 4.03 3588.3 - 158892 - - - 1.1619 - 2.627 0.558 - 181.7 1 1 0 0.0025 21 0 0 0 6.29E+05 5.76E+07 - - - 7.076 0.978 221125_WJC_METTL3_EV_vs_WT_F05.22174.22174.4 0.0484 5/120 K.YRPQTLNDLISHQDILSTIQK.F "sp|P40937|RFC5_HUMAN,tr|F5H0U6|F5H0U6_HUMAN,tr|C9JH72|C9JH72_HUMAN,tr|F5H304|F5H304_HUMAN" 4 2482.318 0.87 72404 22174 4 2482.328572 621.5868 Replication factor C subunit 5 OS=Homo sapiens OX=9606 GN=RFC5 PE=1 SV=1 6.75 3588.5 - 145477 - - - 4.2642 - 1.356 0.265 - 12.7 1 2 0 0.0106 21 0 0 0 8.69E+05 9.99E+05 - - - 1.6303 0.9999 221125_WJC_METTL3_EV_vs_WT_F05.22176.22176.3 4.23E-05 14/96 K.QYNGVPLDGR[166.11]PMNIQLVTSQIDAQR[166.11].R "sp|Q86V81|THOC4_HUMAN,tr|E9PB61|E9PB61_HUMAN" 2 2832.4456 0.74 72406 22176 3 2832.454669 945.1558 THO complex subunit 4 OS=Homo sapiens OX=9606 GN=ALYREF PE=1 SV=3 5.96 3588.7 - 136277 - - - 3.2191 - 2.527 0.56 - 107.6 1 2 0 0.0091 25 0 0 0 4.95E+08 6.72E+08 - - - 6.9137 1 221125_WJC_METTL3_EV_vs_WT_F05.22181.22181.3 1.18E-10 16/56 K.HSGNITFDEIVNIAR.Q sp|P30050|RL12_HUMAN 1 1684.8533 1.49 72409 22181 3 1684.857742 562.625 60S ribosomal protein L12 OS=Homo sapiens OX=9606 GN=RPL12 PE=1 SV=1 5.32 3589.3 - 984660 - - - 2.6465 - 3.428 0.688 - 355.6 1 2 0 0.0045 15 0 0 0 1.48E+08 9.97E+07 - - - 9.424 1 221125_WJC_METTL3_EV_vs_WT_F05.22182.22182.3 9.57E-10 18/56 K.HSGNITFDEIVNIAR[166.11].Q sp|P30050|RL12_HUMAN 1 1694.8616 1.49 72410 22182 3 1694.864812 565.9611 60S ribosomal protein L12 OS=Homo sapiens OX=9606 GN=RPL12 PE=1 SV=1 5.32 3589.4 - 644466 - - - 1.9229 - 3.525 0.66 - 605.6 1 2 0 0.0033 15 0 0 0 1.48E+08 9.97E+07 - - - 9.1849 0.9999 221125_WJC_METTL3_EV_vs_WT_F05.22183.22183.3 3.07E-09 16/96 K.QYNGVPLDGRPMNIQLVTSQIDAQR.R "sp|Q86V81|THOC4_HUMAN,tr|E9PB61|E9PB61_HUMAN" 2 2812.429 0.74 72411 22183 3 2812.438182 938.4836 THO complex subunit 4 OS=Homo sapiens OX=9606 GN=ALYREF PE=1 SV=3 5.96 3589.6 - 404962 - - - 3.2609 - 2.745 0.592 - 141 1 2 0 0.0092 25 0 0 0 4.95E+08 6.72E+08 - - - 7.4608 1 221125_WJC_METTL3_EV_vs_WT_F05.22189.22189.3 9.39E-10 13/56 K.KEENLADWYSQVITK.S sp|P07814|SYEP_HUMAN 1 1822.9101 0.91 72417 22189 3 1822.915291 608.644 Bifunctional glutamate\proline--tRNA ligase OS=Homo sapiens OX=9606 GN=EPRS1 PE=1 SV=5 4.68 3590.4 - 178193 - - - 2.8317 - 2.545 0.647 - 218.5 1 2 0 0.0052 15 0 0 0 2.13E+07 2.36E+07 - - - 8.1895 0.9864 221125_WJC_METTL3_EV_vs_WT_F05.22192.22192.4 0.0326 5/108 R.GLLQDDAHPTLVTYADHSK[136.11].L "sp|Q86U44|MTA70_HUMAN,tr|F5H6D8|F5H6D8_HUMAN,tr|H0YFV6|H0YFV6_HUMAN,tr|B4DTN4|B4DTN4_HUMAN" 4 2088.0367 0.001 72420 22192 4 2088.044187 523.0165 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 5.13 3590.8 - 109829 - - - 3.5699 - 1.384 0.263 - 18.7 1 2 0 0.0075 19 0 0 0 0.00E+00 3.45E+06 - - - 1.623 0.9854 221125_WJC_METTL3_EV_vs_WT_F05.22198.22198.3 0.000243 Dec-52 K.LLHHLSDLALTLPT.D "sp|Q86U44|MTA70_HUMAN,tr|B4E349|B4E349_HUMAN,tr|F5H6D8|F5H6D8_HUMAN,tr|H0YFV6|H0YFV6_HUMAN,tr|B4DTN4|B4DTN4_HUMAN" 5 1542.877 - 72424 22198 3 1542.880908 515.2996 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 5.97 3591.6 - 436339 - - - 2.5465 - 2.831 0.412 - 152.8 1 1 0 0.0039 14 0 0 0 - - - - - 5.8978 0.9992 221125_WJC_METTL3_EV_vs_WT_F05.22202.22202.3 0.0133 Sep-68 K.SSGPTSLFAVTVAPPGAR[166.11].Q "sp|Q00839|HNRPU_HUMAN,tr|A0A1W2PP35|A0A1W2PP35_HUMAN,tr|A0A1W2PPS1|A0A1W2PPS1_HUMAN,tr|A0A1W2PP22|A0A1W2PP22_HUMAN,tr|A0A1X7SBS1|A0A1X7SBS1_HUMAN" 5 1723.9133 1.24 72426 22202 3 1723.916854 575.645 Heterogeneous nuclear ribonucleoprotein U OS=Homo sapiens OX=9606 GN=HNRNPU PE=1 SV=6 9.47 3592.1 - 353311 - - - 2.0883 - 2.035 0.333 - 84.5 1 2 0 0.0036 18 0 0 0 1.05E+07 8.50E+06 - - - 4.0208 1 221125_WJC_METTL3_EV_vs_WT_F05.22203.22203.3 6.94E-10 21/120 R.KYTLPPGVDPTQVSSSLSPEGTLTVEAPMPK.L "sp|P04792|HSPB1_HUMAN,tr|A0A6Q8PGK1|A0A6Q8PGK1_HUMAN" 2 3225.6479 2.71 72427 22203 3 3225.649358 1076.2232 Heat shock protein beta-1 OS=Homo sapiens OX=9606 GN=HSPB1 PE=1 SV=2 4.68 3592.3 - 199964 - - - 0.4529 - 3.953 0.639 - 201.3 1 2 0 0.0015 31 0 0 0 1.27E+07 4.71E+06 - - - 8.826 0.9998 221125_WJC_METTL3_EV_vs_WT_F05.22207.22207.3 7.11E-05 Jun-56 R.GPSLNPVLDYDHGSR.S "sp|P43243|MATR3_HUMAN,tr|A8MXP9|A8MXP9_HUMAN,tr|D6R991|D6R991_HUMAN,tr|A0A0R4J2E8|A0A0R4J2E8_HUMAN,tr|D6REM6|D6REM6_HUMAN" 5 1625.7798 2.22 72431 22207 3 1625.782095 542.9339 Matrin-3 OS=Homo sapiens OX=9606 GN=MATR3 PE=1 SV=2 5.21 3592.8 - 79124.4 - - - 1.4215 - 1.376 0.483 - 33.1 1 2 0 0.0023 15 0 0 0 8.99E+05 4.04E+05 - - - 4.7572 0.9908 221125_WJC_METTL3_EV_vs_WT_F05.22220.22220.3 0.227 Sep-96 K.QYNGVPLDGR[166.11]PMNIQLVTSQIDAQR.R "sp|Q86V81|THOC4_HUMAN,tr|E9PB61|E9PB61_HUMAN" 2 2822.4373 - 72440 22220 3 2822.438511 941.8197 THO complex subunit 4 OS=Homo sapiens OX=9606 GN=ALYREF PE=1 SV=3 5.96 3594.4 - 160413 - - - 0.4358 - 1.217 0.257 - 24.9 1 2 0 0.0012 25 0 0 0 - - - - - 1.8568 0.9998 221125_WJC_METTL3_EV_vs_WT_F05.22225.22225.4 0.00245 15/144 K.QYNGVPLDGRPMNIQLVTSQIDAQR.R "sp|Q86V81|THOC4_HUMAN,tr|E9PB61|E9PB61_HUMAN" 2 2812.429 0.58 72443 22225 4 2812.431642 704.1145 THO complex subunit 4 OS=Homo sapiens OX=9606 GN=ALYREF PE=1 SV=3 5.96 3595.1 - 1.88E+06 - - - 0.9355 - 2.673 0.381 - 151.4 1 2 0 0.0026 25 0 0 0 5.57E+07 9.52E+07 - - - 2.8543 0.9997 221125_WJC_METTL3_EV_vs_WT_F05.22231.22231.4 2.88E-05 14/102 K.VTMQNLNDRLASYLDKVR.A "sp|P13645|K1C10_HUMAN,sp|P02533|K1C14_HUMAN,sp|P08779|K1C16_HUMAN,tr|A0A1B0GVI3|A0A1B0GVI3_HUMAN" 4 2135.1157 583 72447 22231 4 2135.116977 534.7862 "Keratin, type I cytoskeletal 10 OS=Homo sapiens OX=9606 GN=KRT10 PE=1 SV=6" 8.56 3595.9 - 413869 - - - 0.5878 - 2.59 0.429 - 169.9 1 2 2 0.0013 18 0 0 0 1.08E+07 1.85E+04 - - - 3.2857 1 221125_WJC_METTL3_EV_vs_WT_F05.22233.22233.2 9.72E-10 16/28 K.HSGNITFDEIVNIAR.Q sp|P30050|RL12_HUMAN 1 1684.8533 1.53 72449 22233 2 1684.854559 843.4339 60S ribosomal protein L12 OS=Homo sapiens OX=9606 GN=RPL12 PE=1 SV=1 5.32 3596.2 - 415737 - - - 0.7573 - 3.201 0.619 - 692.8 1 2 0 0.0013 15 0 0 0 7.27E+06 4.73E+06 - - - 6.473 0.9996 221125_WJC_METTL3_EV_vs_WT_F05.22235.22235.4 0.0216 6/156 R.FIPDDITFDDEPK[136.11]DVASEVNLTAYK[136.11]PK[136.11].Y "sp|Q9H501|ESF1_HUMAN,tr|A0A087WX71|A0A087WX71_HUMAN" 2 3090.55 0.84 72451 22235 4 3090.549834 773.6448 ESF1 homolog OS=Homo sapiens OX=9606 GN=ESF1 PE=1 SV=1 4.09 3596.5 - 265880 - - - -0.0421 - 1.325 0.443 - 12.5 1 2 1 -0.0001 27 0 0 0 3.85E+06 4.57E+06 - - - 3.1699 0.9999 221125_WJC_METTL3_EV_vs_WT_F05.22238.22238.4 2.83E-05 16/144 K.QYNGVPLDGR[166.11]PMNIQLVTSQIDAQR[166.11].R "sp|Q86V81|THOC4_HUMAN,tr|E9PB61|E9PB61_HUMAN" 2 2832.4456 0.58 72452 22238 4 2832.447241 709.1187 THO complex subunit 4 OS=Homo sapiens OX=9606 GN=ALYREF PE=1 SV=3 5.96 3596.9 - 4.61E+06 - - - 0.5967 - 2.966 0.39 - 150.6 1 2 0 0.0017 25 0 0 0 5.57E+07 9.53E+07 - - - 2.966 0.9999 221125_WJC_METTL3_EV_vs_WT_F05.22244.22244.4 2.56E-05 13/84 R.GPSWDPFR[166.11]DWYPHSR[166.11].L "sp|P04792|HSPB1_HUMAN,tr|A0A6Q8PGY2|A0A6Q8PGY2_HUMAN,tr|A0A6Q8PHJ6|A0A6Q8PHJ6_HUMAN,tr|A0A6Q8PHA6|A0A6Q8PHA6_HUMAN,tr|A0A6Q8PF43|A0A6Q8PF43_HUMAN,tr|A0A6Q8PFK8|A0A6Q8PFK8_HUMAN,tr|A0A6Q8PGK1|A0A6Q8PGK1_HUMAN,tr|A0A6Q8PH65|A0A6Q8PH65_HUMAN,tr|A0A6Q8PFE7|A0A6Q8PFE7_HUMAN" 9 1921.8763 1.69 72458 22244 4 1921.876217 481.4764 Heat shock protein beta-1 OS=Homo sapiens OX=9606 GN=HSPB1 PE=1 SV=2 6.75 3597.6 - 172819 - - - -0.0463 - 2.111 0.507 - 132 1 2 1 -0.0001 15 0 0 0 1.53E+07 9.02E+06 - - - 3.9062 1 221125_WJC_METTL3_EV_vs_WT_F05.22254.22254.3 3.67E-11 24/72 K.DTSEDIEELVEPVAAHGPK[136.11].L "sp|Q99460|PSMD1_HUMAN,tr|A0A7I2V523|A0A7I2V523_HUMAN,tr|A0A7I2V641|A0A7I2V641_HUMAN,tr|A0A087WW66|A0A087WW66_HUMAN,tr|A0A7P0MW50|A0A7P0MW50_HUMAN,tr|A0A7I2V479|A0A7I2V479_HUMAN" 6 2042.9888 0.7 72464 22254 3 2042.991652 682.0035 26S proteasome non-ATPase regulatory subunit 1 OS=Homo sapiens OX=9606 GN=PSMD1 PE=1 SV=2 4.08 3599 - 1.47E+06 - - - 1.4058 - 3.342 0.588 - 627.6 1 2 0 0.0029 19 0 0 0 2.45E+07 3.51E+07 - - - 8.0591 0.9994 221125_WJC_METTL3_EV_vs_WT_F05.22255.22255.4 0.0268 13/84 R.GPSWDPFRDWYPHSR.L "sp|P04792|HSPB1_HUMAN,tr|A0A6Q8PGY2|A0A6Q8PGY2_HUMAN,tr|A0A6Q8PHJ6|A0A6Q8PHJ6_HUMAN,tr|A0A6Q8PHA6|A0A6Q8PHA6_HUMAN,tr|A0A6Q8PF43|A0A6Q8PF43_HUMAN,tr|A0A6Q8PFK8|A0A6Q8PFK8_HUMAN,tr|A0A6Q8PGK1|A0A6Q8PGK1_HUMAN,tr|A0A6Q8PH65|A0A6Q8PH65_HUMAN,tr|A0A6Q8PFE7|A0A6Q8PFE7_HUMAN" 9 1901.8598 1.69 72465 22255 4 1901.860203 476.4722 Heat shock protein beta-1 OS=Homo sapiens OX=9606 GN=HSPB1 PE=1 SV=2 6.75 3599.1 - 620537 - - - 0.2298 - 1.745 0.409 - 127 1 2 1 0.0004 15 0 0 0 1.53E+07 9.02E+06 - - - 2.985 1 221125_WJC_METTL3_EV_vs_WT_F05.22256.22256.3 7.76E-11 21/72 K.DTSEDIEELVEPVAAHGPK.L "sp|Q99460|PSMD1_HUMAN,tr|A0A7I2V523|A0A7I2V523_HUMAN,tr|A0A7I2V641|A0A7I2V641_HUMAN,tr|A0A087WW66|A0A087WW66_HUMAN,tr|A0A7P0MW50|A0A7P0MW50_HUMAN,tr|A0A7I2V479|A0A7I2V479_HUMAN" 6 2034.9746 0.7 72466 22256 3 2034.974943 679.3321 26S proteasome non-ATPase regulatory subunit 1 OS=Homo sapiens OX=9606 GN=PSMD1 PE=1 SV=2 4.08 3599.2 - 1.13E+06 - - - 0.1784 - 3.512 0.696 - 490.1 1 2 0 0.0004 19 0 0 0 2.45E+07 3.48E+07 - - - 9.3858 1 221125_WJC_METTL3_EV_vs_WT_F05.22260.22260.3 7.58E-10 15/80 K.ELSSTEAQLHDAQELLQEETR.A "sp|Q7Z406|MYH14_HUMAN,tr|A0A0C4DFM8|A0A0C4DFM8_HUMAN" 2 2426.1561 1.77 72470 22260 3 2426.161388 809.726 Myosin-14 OS=Homo sapiens OX=9606 GN=MYH14 PE=1 SV=2 4.14 3599.8 - 190511 - - - 2.1685 - 3.366 0.626 - 217.7 1 2 0 0.0053 21 0 0 0 3.27E+06 1.85E+06 - - - 8.4277 0.9997 221125_WJC_METTL3_EV_vs_WT_F05.22262.22262.2 0.000668 22-Sep K.NIEDVIAQGIGK[136.11].L "sp|P05387|RLA2_HUMAN,tr|H0YDD8|H0YDD8_HUMAN" 2 1263.6914 1.3 72472 22262 2 1263.688925 632.853 60S acidic ribosomal protein P2 OS=Homo sapiens OX=9606 GN=RPLP2 PE=1 SV=1 4.37 3600 - 116602 - - - -1.9712 - 1.923 0.519 - 165.9 1 2 0 -0.0025 12 0 0 0 9.48E+06 7.30E+06 - - - 4.594 0.9999 221125_WJC_METTL3_EV_vs_WT_F05.22265.22265.4 7.45E-10 25/126 K.C[160.03]QEVISWLDANTLAEK[136.11]DEFEHK[136.11].R "sp|P0DMV8|HS71A_HUMAN,sp|P0DMV9|HS71B_HUMAN,tr|V9GZ37|V9GZ37_HUMAN,tr|A0A0G2JIW1|A0A0G2JIW1_HUMAN" 4 2677.2665 0.11 72473 22265 4 2677.267192 670.3239 Heat shock 70 kDa protein 1A OS=Homo sapiens OX=9606 GN=HSPA1A PE=1 SV=1 4.35 3600.4 - 4.08E+06 - - - 0.2652 - 4.037 0.607 - 518.3 1 2 1 0.0007 22 0 0 0 1.02E+07 9.33E+07 - - - 4.9657 1 221125_WJC_METTL3_EV_vs_WT_F05.22266.22266.4 4.63E-10 34/126 K.QDLPNAMNAAEITDKLGLHSLR.H "sp|P84077|ARF1_HUMAN,sp|P61204|ARF3_HUMAN,tr|H0YGG7|H0YGG7_HUMAN" 3 2406.2325 1.16 72474 22266 4 2406.234988 602.5654 ADP-ribosylation factor 1 OS=Homo sapiens OX=9606 GN=ARF1 PE=1 SV=2 5.38 3600.6 - 1.40E+06 - - - 1.0161 - 5.634 0.657 - 1258.9 1 2 1 0.0024 22 0 0 0 7.95E+06 6.85E+06 - - - 5.5095 1 221125_WJC_METTL3_EV_vs_WT_F05.22267.22267.4 1.74E-08 32/126 K.QDLPNAMNAAEITDK[136.11]LGLHSLR[166.11].H "sp|P84077|ARF1_HUMAN,sp|P61204|ARF3_HUMAN,tr|H0YGG7|H0YGG7_HUMAN" 3 2424.255 1.16 72475 22267 4 2424.25482 607.071 ADP-ribosylation factor 1 OS=Homo sapiens OX=9606 GN=ARF1 PE=1 SV=2 5.38 3600.7 - 1.08E+06 - - - -0.0796 - 5.101 0.624 - 990 1 2 1 -0.0002 22 0 0 0 7.95E+06 6.85E+06 - - - 5.1904 0.9999 221125_WJC_METTL3_EV_vs_WT_F05.22269.22269.4 4.85E-05 17/126 K.C[160.03]QEVISWLDANTLAEKDEFEHK.R "sp|P0DMV8|HS71A_HUMAN,sp|P0DMV9|HS71B_HUMAN,tr|V9GZ37|V9GZ37_HUMAN,tr|A0A0G2JIW1|A0A0G2JIW1_HUMAN" 4 2661.2381 0.11 72477 22269 4 2661.235056 666.3168 Heat shock 70 kDa protein 1A OS=Homo sapiens OX=9606 GN=HSPA1A PE=1 SV=1 4.35 3600.9 - 444105 - - - -1.1371 - 3.344 0.555 - 276.8 1 2 1 -0.003 22 0 0 0 1.02E+07 9.33E+07 - - - 4.4509 0.9998 221125_WJC_METTL3_EV_vs_WT_F05.22273.22273.3 6.36E-08 Nov-56 R.GPSWDPFRDWYPHSR.L "sp|P04792|HSPB1_HUMAN,tr|A0A6Q8PGY2|A0A6Q8PGY2_HUMAN,tr|A0A6Q8PHJ6|A0A6Q8PHJ6_HUMAN,tr|A0A6Q8PHA6|A0A6Q8PHA6_HUMAN,tr|A0A6Q8PF43|A0A6Q8PF43_HUMAN,tr|A0A6Q8PFK8|A0A6Q8PFK8_HUMAN,tr|A0A6Q8PGK1|A0A6Q8PGK1_HUMAN,tr|A0A6Q8PH65|A0A6Q8PH65_HUMAN,tr|A0A6Q8PFE7|A0A6Q8PFE7_HUMAN" 9 1901.8598 1.44 72481 22273 3 1901.855768 634.9605 Heat shock protein beta-1 OS=Homo sapiens OX=9606 GN=HSPB1 PE=1 SV=2 6.75 3601.5 - 259933 - - - -2.1022 - 2.407 0.542 - 120.9 1 2 1 -0.004 15 0 0 0 4.62E+06 3.20E+06 - - - 6.8737 0.9999 221125_WJC_METTL3_EV_vs_WT_F05.22274.22274.3 2.29E-08 14/56 R.GPSWDPFR[166.11]DWYPHSR[166.11].L "sp|P04792|HSPB1_HUMAN,tr|A0A6Q8PGY2|A0A6Q8PGY2_HUMAN,tr|A0A6Q8PHJ6|A0A6Q8PHJ6_HUMAN,tr|A0A6Q8PHA6|A0A6Q8PHA6_HUMAN,tr|A0A6Q8PF43|A0A6Q8PF43_HUMAN,tr|A0A6Q8PFK8|A0A6Q8PFK8_HUMAN,tr|A0A6Q8PGK1|A0A6Q8PGK1_HUMAN,tr|A0A6Q8PH65|A0A6Q8PH65_HUMAN,tr|A0A6Q8PFE7|A0A6Q8PFE7_HUMAN" 9 1921.8763 1.44 72482 22274 3 1921.876878 641.6327 Heat shock protein beta-1 OS=Homo sapiens OX=9606 GN=HSPB1 PE=1 SV=2 6.75 3601.6 - 222920 - - - 0.2976 - 2.656 0.603 - 207.9 1 2 1 0.0006 15 0 0 0 4.62E+06 3.20E+06 - - - 7.8116 0.9993 221125_WJC_METTL3_EV_vs_WT_F05.22284.22284.3 0.0216 Oct-60 R.HGVQELEIELQSQLSK.K "sp|P35527|K1C9_HUMAN,tr|K7EQQ3|K7EQQ3_HUMAN" 2 1836.9581 63.73 72489 22284 3 1836.961548 613.3267 "Keratin, type I cytoskeletal 9 OS=Homo sapiens OX=9606 GN=KRT9 PE=1 SV=3" 4.75 3602.9 - 183671 - - - 1.8542 - 1.821 0.35 - 34.6 1 2 0 0.0034 16 0 0 0 2.11E+06 3.31E+04 - - - 3.9792 0.8708 221125_WJC_METTL3_EV_vs_WT_F05.22287.22287.3 0.0154 Oct-72 R.DNPHFQSGETSIVISDVLK[136.11].G "sp|Q07157|ZO1_HUMAN,tr|A0A087X0K9|A0A087X0K9_HUMAN,tr|G5E9E7|G5E9E7_HUMAN,tr|A0A0G2JNH2|A0A0G2JNH2_HUMAN,tr|H0YKB1|H0YKB1_HUMAN,tr|G3V1L9|G3V1L9_HUMAN,tr|A0A7I2V5U5|A0A7I2V5U5_HUMAN" 7 2093.052 0.18 72491 22287 3 2094.050209 698.6913 Tight junction protein ZO-1 OS=Homo sapiens OX=9606 GN=TJP1 PE=1 SV=3 4.54 3603.2 - 488333 - - - 476.8921 - 1.403 0.335 - 54.6 1 2 0 0.9982 19 0 0 0 2.55E+06 1.44E+07 - - - 2.8303 1 221125_WJC_METTL3_EV_vs_WT_F05.22288.22288.3 1.62E-09 18/88 K.TPADTGFAFPDWAYK[136.11]PESSPGSR[166.11].Q sp|P50548|ERF_HUMAN 1 2501.1618 1.2 72492 22288 3 2501.160617 834.7279 ETS domain-containing transcription factor ERF OS=Homo sapiens OX=9606 GN=ERF PE=1 SV=2 4.56 3603.3 - 377912 - - - -0.4826 - 3.541 0.653 - 193.3 1 2 0 -0.0012 23 0 0 0 7.89E+06 6.59E+06 - - - 8.7862 0.9999 221125_WJC_METTL3_EV_vs_WT_F05.22292.22292.2 1.29E-06 13/22 K.NIEDVIAQGIGK.L "sp|P05387|RLA2_HUMAN,tr|H0YDD8|H0YDD8_HUMAN" 2 1255.6772 1.3 72494 22292 2 1255.677919 628.8459 60S acidic ribosomal protein P2 OS=Homo sapiens OX=9606 GN=RPLP2 PE=1 SV=1 4.37 3603.9 - 692196 - - - 0.5599 - 2.414 0.57 - 383.5 1 2 0 0.0007 12 0 0 0 9.48E+06 7.30E+06 - - - 5.5696 1 221125_WJC_METTL3_EV_vs_WT_F05.22296.22296.3 8.53E-12 18/64 R.K[136.11]VDIIADAAYSIFQK[136.11]PK[136.11].S sp|Q6YN16|HSDL2_HUMAN 1 1930.099 0.51 72498 22296 3 1930.102023 644.3736 Hydroxysteroid dehydrogenase-like protein 2 OS=Homo sapiens OX=9606 GN=HSDL2 PE=1 SV=1 8.43 3604.4 - 222798 - - - 1.5662 - 3.474 0.7 - 343.8 1 2 0 0.003 17 0 0 0 7.20E+06 1.42E+07 - - - 9.4895 0.9998 221125_WJC_METTL3_EV_vs_WT_F05.22306.22306.3 4.48E-06 Oct-60 K.HEDLK[136.11]DMLEFPAQELR[166.11].K sp|O00267|SPT5H_HUMAN 1 1987.9792 1.4 72506 22306 3 1987.982768 663.667 Transcription elongation factor SPT5 OS=Homo sapiens OX=9606 GN=SUPT5H PE=1 SV=1 4.5 3605.7 - 155389 - - - 1.7787 - 2.365 0.523 - 129.4 1 2 1 0.0035 16 0 0 0 1.54E+06 1.10E+06 - - - 6.5786 1 221125_WJC_METTL3_EV_vs_WT_F05.22311.22311.3 3.45E-09 20/72 C.HIFASFNDTFVHVTDLSGK.E "sp|P62263|RS14_HUMAN,tr|A0A2R8Y811|A0A2R8Y811_HUMAN,tr|E5RH77|E5RH77_HUMAN" 3 2134.0484 1.41 72509 22311 3 2134.046757 712.3567 40S ribosomal protein S14 OS=Homo sapiens OX=9606 GN=RPS14 PE=1 SV=3 5.98 3606.4 - 809732 - - - -0.7483 - 3.746 0.632 - 284.4 1 1 0 -0.0016 19 0 0 0 1.36E+07 9.63E+06 - - - 8.8304 1 221125_WJC_METTL3_EV_vs_WT_F05.22312.22312.3 1.47E-05 16/60 R.HATALEELSEQLEQAK[136.11].R sp|P35580|MYH10_HUMAN 1 1803.9094 1.05 72510 22312 3 1803.910218 602.3104 Myosin-10 OS=Homo sapiens OX=9606 GN=MYH10 PE=1 SV=3 4.48 3606.5 - 579828 - - - 0.449 - 3.384 0.559 - 508.8 1 2 0 0.0008 16 0 0 0 2.52E+07 2.39E+07 - - - 7.9 1 221125_WJC_METTL3_EV_vs_WT_F05.22313.22313.3 1.15E-16 25/96 K.EQASHLGGAVFSGAGNIAAATGLVK.R "sp|Q16143|SYUB_HUMAN,tr|G4Y816|G4Y816_HUMAN" 2 2325.2077 1.52 72511 22313 3 2325.209564 776.0765 Beta-synuclein OS=Homo sapiens OX=9606 GN=SNCB PE=1 SV=1 6.85 3606.7 - 569169 - - - 0.7978 - 4.322 0.704 - 492.5 1 2 0 0.0019 25 0 0 0 1.04E+08 6.84E+07 - - - 9.7559 1 221125_WJC_METTL3_EV_vs_WT_F05.22314.22314.4 5.32E-10 21/96 R.K[136.11]VDIIADAAYSIFQK[136.11]PK[136.11].S sp|Q6YN16|HSDL2_HUMAN 1 1930.099 0.57 72512 22314 4 1930.099859 483.532 Hydroxysteroid dehydrogenase-like protein 2 OS=Homo sapiens OX=9606 GN=HSDL2 PE=1 SV=1 8.43 3606.8 - 511985 - - - 0.4451 - 3.097 0.633 - 432.1 1 2 0 0.0009 17 0 0 0 3.91E+06 6.82E+06 - - - 5.1279 0.9997 221125_WJC_METTL3_EV_vs_WT_F05.22315.22315.3 8.58E-07 13/68 R.RPSSLQSLFGLPEAAGAR.D "sp|P39880|CUX1_HUMAN,tr|A0A2R8Y852|A0A2R8Y852_HUMAN,tr|A0A2R8YDI1|A0A2R8YDI1_HUMAN" 3 1855.9904 1.11 72513 22315 3 1855.998271 619.6708 Homeobox protein cut-like 1 OS=Homo sapiens OX=9606 GN=CUX1 PE=1 SV=3 9.6 3606.9 - 322147 - - - 4.2166 - 2.717 0.493 - 181.6 1 2 0 0.0078 18 0 0 0 2.01E+06 1.81E+06 - - - 6.5232 0.9982 221125_WJC_METTL3_EV_vs_WT_F05.22318.22318.4 5.49E-08 16/108 C.HIFASFNDTFVHVTDLSGK.E "sp|P62263|RS14_HUMAN,tr|A0A2R8Y811|A0A2R8Y811_HUMAN,tr|E5RH77|E5RH77_HUMAN" 3 2134.0484 1.64 72516 22318 4 2134.046266 534.5194 40S ribosomal protein S14 OS=Homo sapiens OX=9606 GN=RPS14 PE=1 SV=3 5.98 3607.3 - 207291 - - - -0.9784 - 3.168 0.59 - 243.8 1 1 0 -0.0021 19 0 0 0 3.43E+06 2.09E+06 - - - 4.7509 0.9993 221125_WJC_METTL3_EV_vs_WT_F05.22321.22321.3 0.0207 Jul-44 K.K[136.11]PGGFDISLFYR[166.11].D "sp|P12956|XRCC6_HUMAN,tr|B1AHC9|B1AHC9_HUMAN" 2 1416.7521 0.31 72519 22321 3 1416.752494 473.258 X-ray repair cross-complementing protein 6 OS=Homo sapiens OX=9606 GN=XRCC6 PE=1 SV=2 8.59 3607.7 - 114224 - - - 0.3092 - 1.796 0.302 - 72.8 1 2 0 0.0004 12 0 0 0 4.63E+05 1.48E+06 - - - 3.53 1 221125_WJC_METTL3_EV_vs_WT_F05.22325.22325.3 9.59E-14 20/60 R.HATALEELSEQLEQAK.R sp|P35580|MYH10_HUMAN 1 1795.8952 1.05 72521 22325 3 1795.897259 599.639 Myosin-10 OS=Homo sapiens OX=9606 GN=MYH10 PE=1 SV=3 4.48 3608.1 - 2.42E+06 - - - 1.142 - 4.028 0.653 - 717 1 2 0 0.0021 16 0 0 0 2.52E+07 2.39E+07 - - - 9.3947 1 221125_WJC_METTL3_EV_vs_WT_F05.22327.22327.3 1.81E-08 15/76 R.SASSTSSLFSSSSQLFPPSR[166.11].L "sp|Q8TB72|PUM2_HUMAN,tr|A0A0C4DG68|A0A0C4DG68_HUMAN" 2 2068.9941 1.47 72523 22327 3 2068.998749 690.672 Pumilio homolog 2 OS=Homo sapiens OX=9606 GN=PUM2 PE=1 SV=2 9.47 3608.4 - 504402 - - - 2.2547 - 3.042 0.618 - 177.9 1 2 0 0.0047 20 0 0 0 2.05E+07 1.39E+07 - - - 8.1278 1 221125_WJC_METTL3_EV_vs_WT_F05.22329.22329.3 5.79E-10 19/108 K.QAQILASEAEK[136.11]AEQINQAAGEASAVLAK[136.11].A "sp|Q9UJZ1|STML2_HUMAN,tr|A0A087WYB4|A0A087WYB4_HUMAN,tr|F2Z2I8|F2Z2I8_HUMAN" 3 2854.5007 6.34 72525 22329 3 2854.503897 952.5075 "Stomatin-like protein 2, mitochondrial OS=Homo sapiens OX=9606 GN=STOML2 PE=1 SV=1" 4.49 3608.7 - 299119 - - - 1.1144 - 3.845 0.645 - 340.7 1 2 1 0.0032 28 0 0 0 1.88E+07 2.96E+06 - - - 8.8287 1 221125_WJC_METTL3_EV_vs_WT_F05.22331.22331.3 8.29E-09 Dec-88 R.ENTEGEYSSLEHESVAGVVESLK.L "sp|P51553|IDH3G_HUMAN,tr|H7C1W2|H7C1W2_HUMAN,tr|E7EQB8|E7EQB8_HUMAN,tr|G5E9Q7|G5E9Q7_HUMAN,tr|E9PF84|E9PF84_HUMAN" 5 2492.1555 0.46 72527 22331 3 2492.161898 831.7258 "Isocitrate dehydrogenase [NAD] subunit gamma, mitochondrial OS=Homo sapiens OX=9606 GN=IDH3G PE=1 SV=1" 4.2 3608.9 - 238458 - - - 2.5841 - 2.54 0.626 - 134.1 1 2 0 0.0064 23 0 0 0 1.66E+06 3.57E+06 - - - 7.7043 0.9879 221125_WJC_METTL3_EV_vs_WT_F05.22333.22333.4 6.39E-05 11/108 C.HIFASFNDTFVHVTDLSGK[136.11].E "sp|P62263|RS14_HUMAN,tr|A0A2R8Y811|A0A2R8Y811_HUMAN,tr|E5RH77|E5RH77_HUMAN" 3 2142.0626 1.63 72529 22333 4 2142.064669 536.5229 40S ribosomal protein S14 OS=Homo sapiens OX=9606 GN=RPS14 PE=1 SV=3 5.98 3609.2 - 176551 - - - 0.9874 - 1.653 0.435 - 41.5 1 1 0 0.0021 19 0 0 0 3.41E+06 2.09E+06 - - - 3.1817 1 221125_WJC_METTL3_EV_vs_WT_F05.22334.22334.2 7.16E-10 14/30 R.HATALEELSEQLEQAK.R sp|P35580|MYH10_HUMAN 1 1795.8952 0.96 72530 22334 2 1795.901752 898.9549 Myosin-10 OS=Homo sapiens OX=9606 GN=MYH10 PE=1 SV=3 4.48 3609.3 - 96430.5 - - - 3.6439 - 3.131 0.745 - 401.8 1 2 0 0.0065 16 0 0 0 1.05E+06 1.10E+06 - - - 7.3476 1 221125_WJC_METTL3_EV_vs_WT_F05.22336.22336.3 2.01E-10 17/76 R.SASSTSSLFSSSSQLFPPSR.L "sp|Q8TB72|PUM2_HUMAN,tr|A0A0C4DG68|A0A0C4DG68_HUMAN" 2 2058.9858 1.46 72531 22336 3 2058.988593 687.3359 Pumilio homolog 2 OS=Homo sapiens OX=9606 GN=PUM2 PE=1 SV=2 9.47 3609.6 - 696761 - - - 1.3497 - 3.281 0.601 - 236.4 1 2 0 0.0028 20 0 0 0 1.90E+07 1.30E+07 - - - 8.1223 1 221125_WJC_METTL3_EV_vs_WT_F05.22339.22339.3 3.32E-06 15/52 K.SLNNQFASFIDKVR.F sp|P04264|K2C1_HUMAN 1 1637.8526 431.55 72533 22339 3 1637.853878 546.9581 "Keratin, type II cytoskeletal 1 OS=Homo sapiens OX=9606 GN=KRT1 PE=1 SV=6" 8.46 3609.9 - 631932 - - - 0.8078 - 2.993 0.608 - 239.4 1 2 1 0.0013 14 0 0 0 7.89E+06 1.83E+04 - - - 8.2316 1 221125_WJC_METTL3_EV_vs_WT_F05.22341.22341.3 1.64E-07 13/60 K.GLDVDSLVIEHIQVNK.A "sp|P18621|RL17_HUMAN,tr|A0A087WWH0|A0A087WWH0_HUMAN,tr|J3QS96|J3QS96_HUMAN,tr|J3QLC8|J3QLC8_HUMAN,tr|J3QQT2|J3QQT2_HUMAN,tr|A0A0A0MRF8|A0A0A0MRF8_HUMAN,tr|J3KRB3|J3KRB3_HUMAN,tr|J3KRX5|J3KRX5_HUMAN,tr|A0A087WXM6|A0A087WXM6_HUMAN,tr|A0A0A6YYL6|A0A0A6YYL6_HUMAN" 10 1777.9574 0.86 72535 22341 3 1777.959159 593.6597 60S ribosomal protein L17 OS=Homo sapiens OX=9606 GN=RPL17 PE=1 SV=3 4.54 3610.2 - 307291 - - - 0.9815 - 2.403 0.593 - 163.4 1 2 0 0.0017 16 0 0 0 2.09E+06 2.42E+06 - - - 7.4004 0.9998 221125_WJC_METTL3_EV_vs_WT_F05.22347.22347.4 2.17E-05 13/144 K.EQASHLGGAVFSGAGNIAAATGLVK.R "sp|Q16143|SYUB_HUMAN,tr|G4Y816|G4Y816_HUMAN" 2 2325.2077 1.77 72539 22347 4 2325.210591 582.3092 Beta-synuclein OS=Homo sapiens OX=9606 GN=SNCB PE=1 SV=1 6.85 3611 - 538886 - - - 1.2395 - 2.029 0.387 - 84.9 1 2 0 0.0029 25 0 0 0 5.42E+06 3.07E+06 - - - 2.8187 1 221125_WJC_METTL3_EV_vs_WT_F05.22348.22348.3 4.73E-12 25/72 K.IIAATIENAQPILQIDNAR.L sp|P08779|K1C16_HUMAN 1 2063.1375 64.2 72540 22348 3 2063.140878 688.7198 "Keratin, type I cytoskeletal 16 OS=Homo sapiens OX=9606 GN=KRT16 PE=1 SV=4" 4.37 3611.1 - 790579 - - - 1.6354 - 3.807 0.559 - 722.1 1 2 0 0.0034 19 0 0 0 1.24E+07 1.93E+05 - - - 8.0557 0.9997 221125_WJC_METTL3_EV_vs_WT_F05.22354.22354.2 7.49E-07 Dec-32 R.AAVEEGIVLGGGC[160.03]ALLR[166.11].C "sp|P10809|CH60_HUMAN,tr|A0A7I2V2X6|A0A7I2V2X6_HUMAN,tr|A0A7I2YQK6|A0A7I2YQK6_HUMAN,tr|A0A7I2V599|A0A7I2V599_HUMAN" 4 1693.9061 1.4 72546 22354 2 1693.909086 847.9603 "60 kDa heat shock protein, mitochondrial OS=Homo sapiens OX=9606 GN=HSPD1 PE=1 SV=2" 4.53 3611.9 - 198608 - - - 1.7858 - 2.852 0.418 - 334.1 1 2 0 0.003 17 0 0 0 2.92E+06 2.08E+06 - - - 4.704 0.9997 221125_WJC_METTL3_EV_vs_WT_F05.22355.22355.3 0.000163 Oct-64 R.AAVEEGIVLGGGC[160.03]ALLR.C "sp|P10809|CH60_HUMAN,tr|A0A7I2V2X6|A0A7I2V2X6_HUMAN,tr|A0A7I2YQK6|A0A7I2YQK6_HUMAN,tr|A0A7I2V599|A0A7I2V599_HUMAN" 4 1683.8978 1.02 72547 22355 3 1683.90153 562.3065 "60 kDa heat shock protein, mitochondrial OS=Homo sapiens OX=9606 GN=HSPD1 PE=1 SV=2" 4.53 3612 - 155526 - - - 2.2204 - 2.127 0.396 - 103.9 1 2 0 0.0037 17 0 0 0 1.06E+06 1.04E+06 - - - 4.8606 1 221125_WJC_METTL3_EV_vs_WT_F05.22358.22358.3 2.94E-19 31/96 K.EQASHLGGAVFSGAGNIAAATGLVK[136.11].R "sp|Q16143|SYUB_HUMAN,tr|G4Y816|G4Y816_HUMAN" 2 2333.2219 1.52 72548 22358 3 2333.223614 778.7479 Beta-synuclein OS=Homo sapiens OX=9606 GN=SNCB PE=1 SV=1 6.85 3612.4 - 4.85E+06 - - - 0.7307 - 5.122 0.741 - 835.5 1 2 0 0.0017 25 0 0 0 1.04E+08 6.84E+07 - - - 10.5591 0.9999 221125_WJC_METTL3_EV_vs_WT_F05.22363.22363.2 3.65E-06 Nov-32 R.AAVEEGIVLGGGC[160.03]ALLR.C "sp|P10809|CH60_HUMAN,tr|A0A7I2V2X6|A0A7I2V2X6_HUMAN,tr|A0A7I2YQK6|A0A7I2YQK6_HUMAN,tr|A0A7I2V599|A0A7I2V599_HUMAN" 4 1683.8978 1.4 72553 22363 2 1683.899599 842.9562 "60 kDa heat shock protein, mitochondrial OS=Homo sapiens OX=9606 GN=HSPD1 PE=1 SV=2" 4.53 3613 - 188793 - - - 1.0737 - 2.469 0.537 - 262.7 1 2 0 0.0018 17 0 0 0 2.92E+06 2.08E+06 - - - 5.2288 1 221125_WJC_METTL3_EV_vs_WT_F05.22364.22364.2 3.39E-09 Nov-38 R.SASSTSSLFSSSSQLFPPSR[166.11].L "sp|Q8TB72|PUM2_HUMAN,tr|A0A0C4DG68|A0A0C4DG68_HUMAN" 2 2068.9941 4.27 72554 22364 2 2068.997062 1035.5043 Pumilio homolog 2 OS=Homo sapiens OX=9606 GN=PUM2 PE=1 SV=2 9.47 3613.1 - 149391 - - - 1.4393 - 2.653 0.618 - 168.6 1 2 0 0.003 20 0 0 0 2.25E+07 5.27E+06 - - - 6.0034 1 221125_WJC_METTL3_EV_vs_WT_F05.22365.22365.3 5.08E-09 16/108 R.HLLPNSGAAATSAAMAAAAATTSSYYGR.D sp|Q9BQ04|RBM4B_HUMAN 1 2681.2868 3.47 72555 22365 3 2681.276075 894.7695 RNA-binding protein 4B OS=Homo sapiens OX=9606 GN=RBM4B PE=1 SV=1 8.6 3613.3 - 136559 - - - -3.9865 - 3.726 0.689 - 187.5 1 2 0 -0.0107 28 0 0 0 7.93E+05 2.28E+05 - - - 9.2448 0.9999 221125_WJC_METTL3_EV_vs_WT_F05.22372.22372.4 2.80E-07 14/108 R.FAHIDGDHLTLLNVYHAFK[136.11].Q sp|O43143|DHX15_HUMAN 1 2218.1415 1.11 72560 22372 4 2218.147032 555.5426 Pre-mRNA-splicing factor ATP-dependent RNA helicase DHX15 OS=Homo sapiens OX=9606 GN=DHX15 PE=1 SV=2 6.26 3614.2 - 386158 - - - 2.5062 - 2.972 0.52 - 189.3 1 2 0 0.0056 19 0 0 0 7.91E+06 7.14E+06 - - - 4.119 0.9999 221125_WJC_METTL3_EV_vs_WT_F05.22379.22379.4 8.94E-05 16/108 R.FAHIDGDHLTLLNVYHAFK.Q sp|O43143|DHX15_HUMAN 1 2210.1273 1.11 72565 22379 4 2210.133889 553.5391 Pre-mRNA-splicing factor ATP-dependent RNA helicase DHX15 OS=Homo sapiens OX=9606 GN=DHX15 PE=1 SV=2 6.26 3615.1 - 363740 - - - 2.9935 - 3.02 0.562 - 255.1 1 2 0 0.0066 19 0 0 0 7.95E+06 7.18E+06 - - - 4.4897 1 221125_WJC_METTL3_EV_vs_WT_F05.22381.22381.3 3.58E-07 14/60 K.K[136.11]VSQEILELLNTTTAK[136.11].E "sp|Q86U44|MTA70_HUMAN,tr|H0YFV6|H0YFV6_HUMAN" 2 1803.0324 0 72567 22381 3 1803.034285 602.0181 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 6.14 3615.4 - 185080 - - - 1.0288 - 3.147 0.565 - 418.2 1 2 0 0.0019 16 0 0 0 2.21E+04 2.07E+07 - - - 7.7803 0.9995 221125_WJC_METTL3_EV_vs_WT_F05.22412.22412.3 6.49E-09 16/72 R.EAGSQK[136.11]DENLALYVENQFR[166.11].E "sp|P02786|TFR1_HUMAN,tr|G3V0E5|G3V0E5_HUMAN" 2 2228.0828 2.86 72592 22412 3 2228.09228 743.7016 Transferrin receptor protein 1 OS=Homo sapiens OX=9606 GN=TFRC PE=1 SV=2 4.41 3619.5 - 434585 - - - 4.2341 - 3.326 0.572 - 307.7 1 2 1 0.0094 19 0 0 0 6.54E+06 2.29E+06 - - - 7.8671 0.9999 221125_WJC_METTL3_EV_vs_WT_F05.22413.22413.4 0.000315 12/210 R.LGSDFGSSR[166.11]PAASLAQPPTPQPPPVNGILVPNGFSK[136.11].L sp|Q7Z5L9|I2BP2_HUMAN 1 3617.8961 2.42 72593 22413 4 3617.903005 905.4813 Interferon regulatory factor 2-binding protein 2 OS=Homo sapiens OX=9606 GN=IRF2BP2 PE=1 SV=2 8.75 3619.6 - 197518 - - - 1.908 - 2.013 0.468 - 45.5 1 2 0 0.0069 36 0 0 0 4.63E+06 1.92E+06 - - - 3.5038 0.9998 221125_WJC_METTL3_EV_vs_WT_F05.22415.22415.3 0.000448 Nov-52 R.KQEEIDVIQEVLEK.H sp|Q9NU22|MDN1_HUMAN 1 1698.904 0.63 72595 22415 3 1698.910366 567.3086 Midasin OS=Homo sapiens OX=9606 GN=MDN1 PE=1 SV=2 4.25 3619.9 - 94746.3 - - - 3.7583 - 2.853 0.459 - 225.3 1 2 0 0.0064 14 0 0 0 2.69E+06 4.29E+06 - - - 6.4417 0.9031 221125_WJC_METTL3_EV_vs_WT_F05.22417.22417.4 0.276 Jun-78 K.DSTFLSTLEHHLSR.Y "sp|Q969V3|NCLN_HUMAN,tr|K7EMW4|K7EMW4_HUMAN,tr|K7ELZ9|K7ELZ9_HUMAN,tr|A0A0C4DGP7|A0A0C4DGP7_HUMAN" 4 1641.8111 0.95 72597 22417 4 1641.816739 411.46 Nicalin OS=Homo sapiens OX=9606 GN=NCLN PE=1 SV=2 5.99 3620.1 - 56477.9 - - - 3.4444 - 1.305 0.177 - 29.1 1 2 0 0.0057 14 0 0 0 6.52E+05 6.85E+05 - - - 0.8619 1 221125_WJC_METTL3_EV_vs_WT_F05.22420.22420.3 2.67E-11 19/76 K.ISDSVLVDIKDTEPLIQTAK.T "sp|P48643|TCPE_HUMAN,tr|E9PCA1|E9PCA1_HUMAN,tr|B7ZAR1|B7ZAR1_HUMAN,tr|E7ENZ3|E7ENZ3_HUMAN" 4 2184.1889 0.64 72598 22420 3 2184.198226 729.0703 T-complex protein 1 subunit epsilon OS=Homo sapiens OX=9606 GN=CCT5 PE=1 SV=1 4.23 3620.6 - 311543 - - - 4.256 - 3.896 0.686 - 444.1 1 2 1 0.0093 20 0 0 0 1.17E+07 1.82E+07 - - - 9.4849 0.9998 221125_WJC_METTL3_EV_vs_WT_F05.22423.22423.3 8.68E-05 Nov-96 K.QYNGVPLDGR[166.11]PMNIQLVTSQIDAQR[166.11].R "sp|Q86V81|THOC4_HUMAN,tr|E9PB61|E9PB61_HUMAN" 2 2832.4456 1.52 72601 22423 3 2832.438803 945.1558 THO complex subunit 4 OS=Homo sapiens OX=9606 GN=ALYREF PE=1 SV=3 5.96 3621 - 261192 - - - -2.3824 - 1.967 0.462 - 47.4 1 2 0 -0.0067 25 0 0 0 3.46E+06 2.28E+06 - - - 5.2454 0.9953 221125_WJC_METTL3_EV_vs_WT_F05.22424.22424.3 4.22E-07 Nov-68 T.LGNQLDGIHLLDPDVVAR[166.11].F sp|Q86U44|MTA70_HUMAN 1 1954.0511 0.02 72602 22424 3 1954.054762 652.3577 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 4.41 3621.1 - 136592 - - - 1.851 - 2.267 0.552 - 109.9 1 1 0 0.0036 18 0 0 0 3.17E+04 1.49E+06 - - - 6.7313 0.9998 221125_WJC_METTL3_EV_vs_WT_F05.22426.22426.3 3.94E-06 Oct-96 K.QYNGVPLDGRPMNIQLVTSQIDAQR.R "sp|Q86V81|THOC4_HUMAN,tr|E9PB61|E9PB61_HUMAN" 2 2812.429 0.76 72604 22426 3 2812.419221 938.4836 THO complex subunit 4 OS=Homo sapiens OX=9606 GN=ALYREF PE=1 SV=3 5.96 3621.4 - 122447 - - - -3.481 - 1.97 0.561 - 52.9 1 2 0 -0.0098 25 0 0 0 3.72E+06 4.89E+06 - - - 6.3518 1 221125_WJC_METTL3_EV_vs_WT_F05.22430.22430.4 0.000168 13/132 R.GFGFVTYSC[160.03]VEEVDAAMC[160.03]ARPHK.V "sp|P51991|ROA3_HUMAN,tr|A0A7I2V5D8|A0A7I2V5D8_HUMAN,tr|A0A7I2V2R3|A0A7I2V2R3_HUMAN,tr|A0A7I2V4J6|A0A7I2V4J6_HUMAN,tr|A0A7I2V4G0|A0A7I2V4G0_HUMAN,tr|A0A7I2V402|A0A7I2V402_HUMAN" 6 2630.1716 1.37 72606 22430 4 2630.175767 658.5502 Heterogeneous nuclear ribonucleoprotein A3 OS=Homo sapiens OX=9606 GN=HNRNPA3 PE=1 SV=2 5.44 3621.9 - 207921 - - - 1.5843 - 1.657 0.542 - 78.2 1 2 0 0.0042 23 0 0 0 3.34E+06 2.44E+06 - - - 4.106 0.9985 221125_WJC_METTL3_EV_vs_WT_F05.22445.22445.3 0.0028 Nov-76 K.ALPGQLKPFETLLSQNQGGK.T "sp|P09211|GSTP1_HUMAN,tr|A0A087X243|A0A087X243_HUMAN" 2 2125.1532 1.71 72616 22445 3 2125.157538 709.3917 Glutathione S-transferase P OS=Homo sapiens OX=9606 GN=GSTP1 PE=1 SV=2 8.64 3623.9 - 216516 - - - 2.0629 - 1.766 0.324 - 135.1 1 2 0 0.0044 20 0 0 0 9.44E+06 5.53E+06 - - - 3.5308 0.9984 221125_WJC_METTL3_EV_vs_WT_F05.22447.22447.3 0.0248 Oct-76 K.ALPGQLK[136.11]PFETLLSQNQGGK[136.11].T "sp|P09211|GSTP1_HUMAN,tr|A0A087X243|A0A087X243_HUMAN" 2 2141.1816 1.7 72618 22447 3 2141.18315 714.7345 Glutathione S-transferase P OS=Homo sapiens OX=9606 GN=GSTP1 PE=1 SV=2 8.64 3624.2 - 125210 - - - 0.7454 - 1.741 0.277 - 75.1 1 2 0 0.0016 20 0 0 0 9.44E+06 5.55E+06 - - - 2.973 0.9994 221125_WJC_METTL3_EV_vs_WT_F05.22448.22448.3 3.98E-05 Jun-60 K.DASDDLDDLNFFNQK[136.11]K[136.11].K sp|P20042|IF2B_HUMAN 1 1899.8821 0.73 72619 22448 3 1899.88922 634.3013 Eukaryotic translation initiation factor 2 subunit 2 OS=Homo sapiens OX=9606 GN=EIF2S2 PE=1 SV=2 3.97 3624.3 - 118129 - - - 3.7281 - 1.425 0.53 - 29.4 1 2 0 0.0071 16 0 0 0 2.74E+06 3.76E+06 - - - 5.3558 0.9996 221125_WJC_METTL3_EV_vs_WT_F05.22454.22454.2 0.000359 22-Oct R.VFIGNLNTLVVK[136.11].K "sp|P0DMR1|HNRC4_HUMAN,sp|P07910|HNRPC_HUMAN,sp|O60812|HNRC1_HUMAN,sp|B2RXH8|HNRC2_HUMAN,sp|B7ZW38|HNRC3_HUMAN,tr|G3V251|G3V251_HUMAN,tr|B4DY08|B4DY08_HUMAN,tr|G3V575|G3V575_HUMAN,tr|B4DSU6|B4DSU6_HUMAN,tr|G3V3K6|G3V3K6_HUMAN,tr|B2R5W2|B2R5W2_HUMAN,tr|G3V4C1|G3V4C1_HUMAN,tr|A0A0G2JPF8|A0A0G2JPF8_HUMAN,tr|A0A0G2JNQ3|A0A0G2JNQ3_HUMAN,tr|G3V576|G3V576_HUMAN,tr|G3V5X6|G3V5X6_HUMAN,tr|G3V2H6|G3V2H6_HUMAN,tr|G3V4W0|G3V4W0_HUMAN,tr|G3V555|G3V555_HUMAN,tr|G3V4M8|G3V4M8_HUMAN,tr|G3V2Q1|G3V2Q1_HUMAN" 21 1323.8006 1.22 72623 22454 2 1323.802852 662.9076 Heterogeneous nuclear ribonucleoprotein C-like 4 OS=Homo sapiens OX=9606 GN=HNRNPCL4 PE=3 SV=1 8.72 3625.1 - 271340 - - - 1.7216 - 1.863 0.472 - 262.3 1 2 0 0.0023 12 0 0 0 4.69E+06 3.85E+06 - - - 4.1636 0.9998 221125_WJC_METTL3_EV_vs_WT_F05.22457.22457.4 0.00948 8/102 K.TEAEIAHIALETLEGHQR[166.11].A "sp|O75955|FLOT1_HUMAN,tr|A2AB10|A2AB10_HUMAN,tr|A0A140T910|A0A140T910_HUMAN,tr|A2AB09|A2AB09_HUMAN,tr|A2AB11|A2AB11_HUMAN,tr|A0A140T9C3|A0A140T9C3_HUMAN,tr|A0A140T9R1|A0A140T9R1_HUMAN,tr|A0A140T957|A0A140T957_HUMAN,tr|A0A140T9B1|A0A140T9B1_HUMAN,tr|A0A140T959|A0A140T959_HUMAN,tr|A2AB12|A2AB12_HUMAN,tr|A0A0G2JJQ6|A0A0G2JJQ6_HUMAN,tr|A0A140T9X0|A0A140T9X0_HUMAN,tr|A2AB13|A2AB13_HUMAN" 14 2027.0311 1.97 72626 22457 4 2027.029698 507.7651 Flotillin-1 OS=Homo sapiens OX=9606 GN=FLOT1 PE=1 SV=3 4.87 3625.5 - 145002 - - - -0.7104 - 1.93 0.386 - 44.5 1 2 0 -0.0014 18 0 0 0 4.07E+06 2.06E+06 - - - 2.8106 1 221125_WJC_METTL3_EV_vs_WT_F05.22461.22461.3 2.15E-08 Dec-92 R.VETGVLK[136.11]PGMVVTFAPVNVTTEVK[136.11].S "sp|P68104|EF1A1_HUMAN,sp|Q5VTE0|EF1A3_HUMAN,tr|A0A7I2V659|A0A7I2V659_HUMAN,tr|A0A7I2V3H3|A0A7I2V3H3_HUMAN,tr|A0A7I2V5N4|A0A7I2V5N4_HUMAN,tr|A0A087WVQ9|A0A087WVQ9_HUMAN" 6 2530.4051 0.31 72628 22461 3 2530.403667 844.4757 Elongation factor 1-alpha 1 OS=Homo sapiens OX=9606 GN=EEF1A1 PE=1 SV=1 6.11 3626 - 290929 - - - -0.5853 - 3.014 0.56 - 100.2 1 2 0 -0.0015 24 0 0 0 4.00E+06 1.29E+07 - - - 7.3455 0.9998 221125_WJC_METTL3_EV_vs_WT_F05.22462.22462.2 1.17E-05 22-Oct R.VFIGNLNTLVVK.K "sp|P0DMR1|HNRC4_HUMAN,sp|P07910|HNRPC_HUMAN,sp|O60812|HNRC1_HUMAN,sp|B2RXH8|HNRC2_HUMAN,sp|B7ZW38|HNRC3_HUMAN,tr|G3V251|G3V251_HUMAN,tr|B4DY08|B4DY08_HUMAN,tr|G3V575|G3V575_HUMAN,tr|B4DSU6|B4DSU6_HUMAN,tr|G3V3K6|G3V3K6_HUMAN,tr|B2R5W2|B2R5W2_HUMAN,tr|G3V4C1|G3V4C1_HUMAN,tr|A0A0G2JPF8|A0A0G2JPF8_HUMAN,tr|A0A0G2JNQ3|A0A0G2JNQ3_HUMAN,tr|G3V576|G3V576_HUMAN,tr|G3V5X6|G3V5X6_HUMAN,tr|G3V2H6|G3V2H6_HUMAN,tr|G3V4W0|G3V4W0_HUMAN,tr|G3V555|G3V555_HUMAN,tr|G3V4M8|G3V4M8_HUMAN,tr|G3V2Q1|G3V2Q1_HUMAN" 21 1315.7864 1.22 72629 22462 2 1315.78437 658.9005 Heterogeneous nuclear ribonucleoprotein C-like 4 OS=Homo sapiens OX=9606 GN=HNRNPCL4 PE=3 SV=1 8.72 3626.1 - 238656 - - - -1.5223 - 2.072 0.531 - 247.4 1 2 0 -0.002 12 0 0 0 4.69E+06 3.85E+06 - - - 4.8792 0.9983 221125_WJC_METTL3_EV_vs_WT_F05.22468.22468.3 0.0138 Aug-64 R.KLFIGGLSFETTDESLR.S "sp|Q32P51|RA1L2_HUMAN,sp|P09651|ROA1_HUMAN,tr|F8W646|F8W646_HUMAN,tr|F8VZ49|F8VZ49_HUMAN,tr|A0A7I2V3R8|A0A7I2V3R8_HUMAN,tr|F8VTQ5|F8VTQ5_HUMAN,tr|A0A7I2YQ85|A0A7I2YQ85_HUMAN,tr|F8W6I7|F8W6I7_HUMAN,tr|A0A7I2V2L6|A0A7I2V2L6_HUMAN,tr|A0A7I2V3W0|A0A7I2V3W0_HUMAN" 10 1911.9942 1.51 72632 22468 3 1911.988124 638.3387 Heterogeneous nuclear ribonucleoprotein A1-like 2 OS=Homo sapiens OX=9606 GN=HNRNPA1L2 PE=2 SV=2 4.68 3626.9 - 106280 - - - -3.1742 - 1.79 0.358 - 95.5 1 2 0 -0.0061 17 0 0 0 1.30E+06 8.60E+05 - - - 4.0005 1 221125_WJC_METTL3_EV_vs_WT_F05.22473.22473.3 2.33E-10 18/104 R.YQDEVFGGFVTEPQEESEEEVEEPEER.Q "sp|Q13283|G3BP1_HUMAN,tr|A0A7I2V5M7|A0A7I2V5M7_HUMAN,tr|A0A7P0P2U7|A0A7P0P2U7_HUMAN,tr|A0A7I2YQU8|A0A7I2YQU8_HUMAN,tr|A0A7I2V651|A0A7I2V651_HUMAN,tr|A0A7I2YQN9|A0A7I2YQN9_HUMAN,tr|A0A7I2V2V1|A0A7I2V2V1_HUMAN" 7 3215.3579 2.14 72636 22473 3 3215.351142 1072.7932 Ras GTPase-activating protein-binding protein 1 OS=Homo sapiens OX=9606 GN=G3BP1 PE=1 SV=1 3.56 3627.5 - 369807 - - - -2.089 - 3.28 0.705 - 256.7 1 2 0 -0.0067 27 0 0 0 5.36E+06 2.51E+06 - - - 9.131 0.9999 221125_WJC_METTL3_EV_vs_WT_F05.22475.22475.3 6.58E-06 10/104 R.YQDEVFGGFVTEPQEESEEEVEEPEER[166.11].Q "sp|Q13283|G3BP1_HUMAN,tr|A0A7I2V5M7|A0A7I2V5M7_HUMAN,tr|A0A7P0P2U7|A0A7P0P2U7_HUMAN,tr|A0A7I2YQU8|A0A7I2YQU8_HUMAN,tr|A0A7I2V651|A0A7I2V651_HUMAN,tr|A0A7I2YQN9|A0A7I2YQN9_HUMAN,tr|A0A7I2V2V1|A0A7I2V2V1_HUMAN" 7 3225.3661 2.14 72637 22475 3 3225.353967 1076.1293 Ras GTPase-activating protein-binding protein 1 OS=Homo sapiens OX=9606 GN=G3BP1 PE=1 SV=1 3.56 3627.7 - 227805 - - - -3.7707 - 2.519 0.607 - 58.5 1 2 0 -0.0122 27 0 0 0 5.36E+06 2.51E+06 - - - 7.4296 1 221125_WJC_METTL3_EV_vs_WT_F05.22482.22482.3 2.93E-10 18/92 R.VETGVLKPGMVVTFAPVNVTTEVK.S "sp|P68104|EF1A1_HUMAN,sp|Q5VTE0|EF1A3_HUMAN,tr|A0A7I2V659|A0A7I2V659_HUMAN,tr|A0A7I2V3H3|A0A7I2V3H3_HUMAN,tr|A0A7I2V5N4|A0A7I2V5N4_HUMAN,tr|A0A087WVQ9|A0A087WVQ9_HUMAN" 6 2514.3767 0.31 72643 22482 3 2514.377928 839.1329 Elongation factor 1-alpha 1 OS=Homo sapiens OX=9606 GN=EEF1A1 PE=1 SV=1 6.11 3628.6 - 385061 - - - 0.4693 - 3.45 0.593 - 259.4 1 2 0 0.0012 24 0 0 0 4.00E+06 1.29E+07 - - - 8.0273 0.8796 221125_WJC_METTL3_EV_vs_WT_F05.22488.22488.2 0.0311 22-Oct T.RFGSTLQLDLEK[136.11].G "sp|Q9Y3T6|R3HC1_HUMAN,tr|A0A0D9SF44|A0A0D9SF44_HUMAN,tr|E5RIK1|E5RIK1_HUMAN,tr|A0A7P0N5L0|A0A7P0N5L0_HUMAN,tr|E5RIQ4|E5RIQ4_HUMAN,tr|A0A0R4J2E2|A0A0R4J2E2_HUMAN" 6 1413.7707 - 72647 22488 2 1413.7684 707.8926 R3H and coiled-coil domain-containing protein 1 OS=Homo sapiens OX=9606 GN=R3HCC1 PE=1 SV=3 6.07 3629.4 - 1.96E+06 - - - -1.6474 - 1.494 0.274 - 233.4 1 1 0 -0.0023 12 0 0 0 - - - - - 2.1203 1 221125_WJC_METTL3_EV_vs_WT_F05.22489.22489.3 5.28E-05 14/96 K.SVPNTPLRPNQQSVVNSSFSELFVK.F "sp|Q15643|TRIPB_HUMAN,tr|H0YJ97|H0YJ97_HUMAN" 2 2773.4399 1.24 72648 22489 3 2773.439261 925.4872 Thyroid receptor-interacting protein 11 OS=Homo sapiens OX=9606 GN=TRIP11 PE=1 SV=3 8.46 3629.5 - 751643 - - - -0.2279 - 3.051 0.472 - 166.5 1 2 0 -0.0006 25 0 0 0 2.23E+07 1.80E+07 - - - 6.3685 0.865 221125_WJC_METTL3_EV_vs_WT_F05.22490.22490.3 2.95E-07 Oct-68 R.TSQNSELNNMQDLVEDYK.K sp|P35908|K22E_HUMAN 1 2126.9426 -1 72649 22490 3 2127.926922 709.9882 "Keratin, type II cytoskeletal 2 epidermal OS=Homo sapiens OX=9606 GN=KRT2 PE=1 SV=2" 3.92 3629.6 - 721704 - - - 462.7741 - 2.513 0.503 - 135.1 1 2 0 0.9843 18 0 0 0 0.00E+00 0.00E+00 - - - 6.1699 1 221125_WJC_METTL3_EV_vs_WT_F05.22491.22491.2 6.44E-13 15/34 R.TSQNSELNNMQDLVEDYK.K sp|P35908|K22E_HUMAN 1 2126.9426 -1 72650 22491 2 2127.926129 1064.4786 "Keratin, type II cytoskeletal 2 epidermal OS=Homo sapiens OX=9606 GN=KRT2 PE=1 SV=2" 3.92 3629.8 - 344473 - - - 462.4013 - 3.52 0.647 - 777.7 1 2 0 0.9835 18 0 0 0 0.00E+00 0.00E+00 - - - 6.6049 0.9999 221125_WJC_METTL3_EV_vs_WT_F05.22492.22492.3 8.33E-07 Oct-60 K.C[160.03]GDLEEELKNVTNNLK.S "sp|P67936|TPM4_HUMAN,tr|A0A2R8Y5V9|A0A2R8Y5V9_HUMAN,tr|A0A5F9UN72|A0A5F9UN72_HUMAN,tr|K7EPB9|K7EPB9_HUMAN,tr|A0A2R8YEU4|A0A2R8YEU4_HUMAN,tr|A0A2R8YGX3|A0A2R8YGX3_HUMAN,tr|K7ENT6|K7ENT6_HUMAN,tr|A0A2R8YH90|A0A2R8YH90_HUMAN,tr|A0A2R8YE05|A0A2R8YE05_HUMAN,tr|A0A2R8YHD2|A0A2R8YHD2_HUMAN" 10 1874.9044 0.17 72651 22492 3 1874.905142 625.9754 Tropomyosin alpha-4 chain OS=Homo sapiens OX=9606 GN=TPM4 PE=1 SV=3 4.41 3629.9 - 259695 - - - 0.4 - 2.124 0.587 - 109.7 1 2 1 0.0007 16 0 0 0 3.16E+06 1.90E+07 - - - 7.0171 1 221125_WJC_METTL3_EV_vs_WT_F05.22496.22496.3 4.53E-06 17/96 K.SVPNTPLR[166.11]PNQQSVVNSSFSELFVK[136.11].F "sp|Q15643|TRIPB_HUMAN,tr|H0YJ97|H0YJ97_HUMAN" 2 2791.4624 1.24 72653 22496 3 2791.465002 931.4947 Thyroid receptor-interacting protein 11 OS=Homo sapiens OX=9606 GN=TRIP11 PE=1 SV=3 8.46 3630.5 - 938857 - - - 0.9454 - 2.975 0.573 - 282.4 1 2 0 0.0026 25 0 0 0 2.23E+07 1.80E+07 - - - 7.4359 1 221125_WJC_METTL3_EV_vs_WT_F05.22497.22497.3 9.99E-11 21/88 R.SSVSHSVLSEMQVIEQETPVSAK.S "sp|Q8N6H7|ARFG2_HUMAN,tr|E9PQP3|E9PQP3_HUMAN,tr|H0YDN9|H0YDN9_HUMAN,tr|G5E9L0|G5E9L0_HUMAN,tr|A0A0D9SF70|A0A0D9SF70_HUMAN" 5 2471.2214 1.55 72654 22497 3 2471.221257 824.7477 ADP-ribosylation factor GTPase-activating protein 2 OS=Homo sapiens OX=9606 GN=ARFGAP2 PE=1 SV=1 4.75 3630.6 - 440745 - - - -0.0453 - 3.81 0.66 - 600.7 1 2 0 -0.0001 23 0 0 0 2.42E+07 1.55E+07 - - - 9.0363 0.9999 221125_WJC_METTL3_EV_vs_WT_F05.22499.22499.3 3.08E-05 Oct-68 K.SSSPAPADIAQTVQEDLR[166.11].T "sp|Q13283|G3BP1_HUMAN,tr|A0A7I2V5M7|A0A7I2V5M7_HUMAN,tr|A0A7P0P2U7|A0A7P0P2U7_HUMAN,tr|A0A7I2YQU8|A0A7I2YQU8_HUMAN,tr|A0A7I2V651|A0A7I2V651_HUMAN,tr|A0A7I2V326|A0A7I2V326_HUMAN,tr|A0A7I2YQN9|A0A7I2YQN9_HUMAN" 7 1893.9308 1.21 72656 22499 3 1893.929353 632.3175 Ras GTPase-activating protein-binding protein 1 OS=Homo sapiens OX=9606 GN=G3BP1 PE=1 SV=1 4.03 3630.9 - 204050 - - - -0.7403 - 2.13 0.428 - 124.4 1 2 0 -0.0014 18 0 0 0 9.32E+07 7.69E+07 - - - 5.1942 0.9946 221125_WJC_METTL3_EV_vs_WT_F05.22500.22500.3 0.00487 Aug-64 K.ELTTEIDNNIEQISSYK.S "sp|P13645|K1C10_HUMAN,tr|A0A1B0GVI3|A0A1B0GVI3_HUMAN" 2 1995.9637 417.62 72657 22500 3 1995.967986 666.3285 "Keratin, type I cytoskeletal 10 OS=Homo sapiens OX=9606 GN=KRT10 PE=1 SV=6" 4 3631 - 174673 - - - 2.1569 - 1.497 0.28 - 72.1 1 2 0 0.0043 17 0 0 0 1.06E+07 2.54E+04 - - - 2.6798 0.9999 221125_WJC_METTL3_EV_vs_WT_F05.22501.22501.3 0.000119 Sep-92 K.K[136.11]LTAGEAC[160.03]AQGLVTEVFPDSTFQK[136.11].E "sp|O75521|ECI2_HUMAN,tr|A0A0C4DGA2|A0A0C4DGA2_HUMAN" 2 2612.3127 1.31 72658 22501 3 2612.310858 871.7782 Enoyl-CoA delta isomerase 2 OS=Homo sapiens OX=9606 GN=ECI2 PE=1 SV=4 4.68 3631.1 - 163086 - - - -0.7067 - 2.268 0.475 - 52.9 1 2 0 -0.0018 24 0 0 0 6.35E+06 4.86E+06 - - - 5.7372 0.9999 221125_WJC_METTL3_EV_vs_WT_F05.22508.22508.3 3.38E-06 16/84 K.EGFGLSENPFASLSPDEQKDEK.K "sp|O15504|NUP42_HUMAN,tr|B4DT96|B4DT96_HUMAN,tr|C9JYA1|C9JYA1_HUMAN" 3 2423.1129 1.92 72663 22508 3 2423.116479 808.7116 Nucleoporin NUP42 OS=Homo sapiens OX=9606 GN=NUP42 PE=1 SV=1 4.08 3632.1 - 424500 - - - 1.4915 - 3.409 0.609 - 285 1 2 1 0.0036 22 0 0 0 9.92E+06 5.17E+06 - - - 8.2364 0.9999 221125_WJC_METTL3_EV_vs_WT_F05.22509.22509.3 0.000382 14/68 K.SSSPAPADIAQTVQEDLR.T "sp|Q13283|G3BP1_HUMAN,tr|A0A7I2V5M7|A0A7I2V5M7_HUMAN,tr|A0A7P0P2U7|A0A7P0P2U7_HUMAN,tr|A0A7I2YQU8|A0A7I2YQU8_HUMAN,tr|A0A7I2V651|A0A7I2V651_HUMAN,tr|A0A7I2V326|A0A7I2V326_HUMAN,tr|A0A7I2YQN9|A0A7I2YQN9_HUMAN" 7 1883.9225 1.21 72664 22509 3 1883.925479 628.9814 Ras GTPase-activating protein-binding protein 1 OS=Homo sapiens OX=9606 GN=G3BP1 PE=1 SV=1 4.03 3632.2 - 618488 - - - 1.5892 - 2.575 0.453 - 215.5 1 2 0 0.003 18 0 0 0 9.32E+07 7.69E+07 - - - 5.9449 1 221125_WJC_METTL3_EV_vs_WT_F05.22510.22510.3 4.26E-13 21/88 R.SSVSHSVLSEMQVIEQETPVSAK[136.11].S "sp|Q8N6H7|ARFG2_HUMAN,tr|E9PQP3|E9PQP3_HUMAN,tr|H0YDN9|H0YDN9_HUMAN,tr|G5E9L0|G5E9L0_HUMAN,tr|A0A0D9SF70|A0A0D9SF70_HUMAN" 5 2479.2356 1.48 72665 22510 3 2479.238283 827.4191 ADP-ribosylation factor GTPase-activating protein 2 OS=Homo sapiens OX=9606 GN=ARFGAP2 PE=1 SV=1 4.75 3632.3 - 465702 - - - 1.0947 - 3.864 0.68 - 491 1 2 0 0.0027 23 0 0 0 2.29E+07 1.55E+07 - - - 9.2916 1 221125_WJC_METTL3_EV_vs_WT_F05.22511.22511.2 1.35E-07 15/32 K.ELTTEIDNNIEQISSYK.S "sp|P13645|K1C10_HUMAN,tr|A0A1B0GVI3|A0A1B0GVI3_HUMAN" 2 1995.9637 999 72666 22511 2 1995.96739 998.9891 "Keratin, type I cytoskeletal 10 OS=Homo sapiens OX=9606 GN=KRT10 PE=1 SV=6" 4 3632.5 - 417356 - - - 1.8583 - 2.955 0.611 - 640 1 2 0 0.0037 17 0 0 0 6.83E+06 0.00E+00 - - - 6.2165 0.9899 221125_WJC_METTL3_EV_vs_WT_F05.22512.22512.3 6.08E-06 Aug-84 K.TC[160.03]NC[160.03]ETEDYGEKFDENDVITC[160.03]F.A "sp|Q00839|HNRPU_HUMAN,tr|A0A1W2PQL0|A0A1W2PQL0_HUMAN,tr|A0A1W2PPL4|A0A1W2PPL4_HUMAN,tr|A0A1W2PQ74|A0A1W2PQ74_HUMAN,tr|Q5RI18|Q5RI18_HUMAN,tr|A0A1W2PP35|A0A1W2PP35_HUMAN,tr|A0A1W2PPS1|A0A1W2PPS1_HUMAN,tr|A0A1W2PRZ7|A0A1W2PRZ7_HUMAN,tr|A0A1W2PPH7|A0A1W2PPH7_HUMAN,tr|A0A1W2PP34|A0A1W2PP34_HUMAN,tr|A0A1X7SBS1|A0A1X7SBS1_HUMAN" 11 2745.0517 1.01 72667 22512 3 2745.051841 916.0245 Heterogeneous nuclear ribonucleoprotein U OS=Homo sapiens OX=9606 GN=HNRNPU PE=1 SV=6 3.66 3632.6 - 269634 - - - 0.0645 - 1.65 0.65 - 48.5 1 1 1 0.0002 22 0 0 0 2.30E+06 2.27E+06 - - - 6.9741 1 221125_WJC_METTL3_EV_vs_WT_F05.22515.22515.3 1.62E-16 21/72 K.R[166.11]EEEEFNTGPLSVLTQSVK[136.11].N "sp|P62316|SMD2_HUMAN,tr|K7ERG4|K7ERG4_HUMAN" 2 2180.108 1.66 72668 22515 3 2180.111686 727.7099 Small nuclear ribonucleoprotein Sm D2 OS=Homo sapiens OX=9606 GN=SNRPD2 PE=1 SV=1 4.49 3633 - 332362 - - - 1.6917 - 3.976 0.734 - 805.7 1 2 0 0.0037 19 0 0 0 1.79E+08 1.07E+08 - - - 10.1134 0.9999 221125_WJC_METTL3_EV_vs_WT_F05.22518.22518.3 5.76E-08 Dec-76 R.TSGNVEDDLIIFPDDC[160.03]EFKR.V sp|Q16186|ADRM1_HUMAN 1 2369.0845 1.49 72671 22518 3 2369.093391 790.7021 Proteasomal ubiquitin receptor ADRM1 OS=Homo sapiens OX=9606 GN=ADRM1 PE=1 SV=2 3.96 3633.4 - 264266 - - - 3.7352 - 2.87 0.59 - 103.8 1 2 0 0.0088 20 0 0 0 2.12E+06 1.42E+06 - - - 7.6733 0.9999 221125_WJC_METTL3_EV_vs_WT_F05.22520.22520.4 0.000595 8/120 K.DHSSLLQGTLAEHFGVLPGPR.D sp|Q5VT52|RPRD2_HUMAN 1 2230.1495 1.32 72673 22520 4 2230.153035 558.5446 Regulation of nuclear pre-mRNA domain-containing protein 2 OS=Homo sapiens OX=9606 GN=RPRD2 PE=1 SV=1 5.99 3633.7 - 123867 - - - 1.6008 - 1.882 0.454 - 34.1 1 2 0 0.0036 21 0 0 0 1.21E+06 9.16E+05 - - - 3.3857 0.8592 221125_WJC_METTL3_EV_vs_WT_F05.22524.22524.2 0.433 26-Jun K.SR[166.11]GLDSQQC[160.03]AQRQR.W sp|C9J442|CV046_HUMAN 1 1698.8208 - 72675 22524 2 1698.819994 850.4177 Uncharacterized protein C22orf46 OS=Homo sapiens OX=9606 GN=C22orf46 PE=5 SV=1 10.26 3634.2 - 1.84E+06 - - - -0.4556 - 1.146 0.136 - 74.8 1 2 2 -0.0008 14 0 0 0 - - - - - 0.3872 1 221125_WJC_METTL3_EV_vs_WT_F05.22525.22525.2 5.44E-09 19/34 K.SSSPAPADIAQTVQEDLR[166.11].T "sp|Q13283|G3BP1_HUMAN,tr|A0A7I2V5M7|A0A7I2V5M7_HUMAN,tr|A0A7P0P2U7|A0A7P0P2U7_HUMAN,tr|A0A7I2YQU8|A0A7I2YQU8_HUMAN,tr|A0A7I2V651|A0A7I2V651_HUMAN,tr|A0A7I2V326|A0A7I2V326_HUMAN,tr|A0A7I2YQN9|A0A7I2YQN9_HUMAN" 7 1893.9308 1.38 72676 22525 2 1893.932518 947.9727 Ras GTPase-activating protein-binding protein 1 OS=Homo sapiens OX=9606 GN=G3BP1 PE=1 SV=1 4.03 3634.4 - 700159 - - - 0.9309 - 3.504 0.678 - 1223.4 1 2 0 0.0018 18 0 0 0 7.60E+07 5.49E+07 - - - 7.1309 1 221125_WJC_METTL3_EV_vs_WT_F05.22526.22526.3 1.44E-12 18/72 K.REEEEFNTGPLSVLTQSVK.N "sp|P62316|SMD2_HUMAN,tr|K7ERG4|K7ERG4_HUMAN" 2 2162.0855 1.67 72677 22526 3 2162.090283 721.7025 Small nuclear ribonucleoprotein Sm D2 OS=Homo sapiens OX=9606 GN=SNRPD2 PE=1 SV=1 4.49 3634.5 - 746338 - - - 2.1993 - 3.303 0.717 - 503.7 1 2 0 0.0048 19 0 0 0 1.79E+08 1.07E+08 - - - 9.468 1 221125_WJC_METTL3_EV_vs_WT_F05.22528.22528.3 1.86E-09 16/80 K.VQALEEANNDLENKIQDWYDK.K sp|P35527|K1C9_HUMAN 1 2534.1925 64.11 72679 22528 3 2534.195911 845.7381 "Keratin, type I cytoskeletal 9 OS=Homo sapiens OX=9606 GN=KRT9 PE=1 SV=3" 4.02 3634.7 - 397511 - - - 1.3413 - 3.71 0.644 - 299 1 2 1 0.0034 21 0 0 0 1.22E+07 1.90E+05 - - - 8.8622 1 221125_WJC_METTL3_EV_vs_WT_F05.22530.22530.3 2.14E-12 21/128 K.STEEQLEEQQQQEEEVEEVEVEQVQVEADAQEK.A sp|Q8N5Z5|KCD17_HUMAN 1 3901.7349 9.74 72681 22530 3 3901.736148 1301.5856 BTB\POZ domain-containing protein KCTD17 OS=Homo sapiens OX=9606 GN=KCTD17 PE=1 SV=3 3.5 3635 - 248372 - - - 0.3275 - 4.123 0.747 - 485.1 1 2 0 0.0013 33 0 0 0 7.91E+06 8.12E+05 - - - 10.127 0.9999 221125_WJC_METTL3_EV_vs_WT_F05.22531.22531.3 3.95E-06 15/60 K.TLSDDLDEAAK[136.11]EFQEK[136.11].H "sp|Q9H0A0|NAT10_HUMAN,tr|A0A087WV29|A0A087WV29_HUMAN" 2 1853.8866 0.92 72682 22531 3 1853.884121 618.9695 RNA cytidine acetyltransferase OS=Homo sapiens OX=9606 GN=NAT10 PE=1 SV=2 4.02 3635.1 - 242076 - - - -1.3118 - 2.74 0.561 - 160.6 1 2 1 -0.0024 16 0 0 0 9.77E+06 1.06E+07 - - - 7.3802 0.9994 221125_WJC_METTL3_EV_vs_WT_F05.22536.22536.2 1.41E-05 28-Jun K.QISNLQQSISDAEQR.G sp|P04264|K2C1_HUMAN 1 1715.8438 999 72687 22536 2 1715.848157 858.9292 "Keratin, type II cytoskeletal 1 OS=Homo sapiens OX=9606 GN=KRT1 PE=1 SV=6" 4.37 3635.8 - 111064 - - - 2.5154 - 1.707 0.512 - 96.9 1 2 0 0.0043 15 0 0 0 1.06E+06 0.00E+00 - - - 4.136 0.9999 221125_WJC_METTL3_EV_vs_WT_F05.22538.22538.4 9.71E-07 9/174 R.TTGIVMDSGDGVTHTVPIYEGYALPHAILR[166.11].L "sp|P63261|ACTG_HUMAN,sp|P60709|ACTB_HUMAN,tr|A0A804GS07|A0A804GS07_HUMAN,tr|I3L3I0|I3L3I0_HUMAN,tr|E7EVS6|E7EVS6_HUMAN,tr|A0A6Q8PFE4|A0A6Q8PFE4_HUMAN,tr|I3L1U9|I3L1U9_HUMAN,tr|A0A2R8YEA7|A0A2R8YEA7_HUMAN,tr|A0A2R8Y793|A0A2R8Y793_HUMAN,tr|I3L4N8|I3L4N8_HUMAN" 10 3192.6153 0.97 72689 22538 4 3192.620164 799.1611 "Actin, cytoplasmic 2 OS=Homo sapiens OX=9606 GN=ACTG1 PE=1 SV=1" 5.2 3636.1 - 96712.3 - - - 1.5219 - 2.285 0.476 - 29.7 1 2 0 0.0049 30 0 0 0 8.02E+06 8.28E+06 - - - 3.6206 1 221125_WJC_METTL3_EV_vs_WT_F05.22541.22541.2 1.95E-11 17/34 K.SSSPAPADIAQTVQEDLR.T "sp|Q13283|G3BP1_HUMAN,tr|A0A7I2V5M7|A0A7I2V5M7_HUMAN,tr|A0A7P0P2U7|A0A7P0P2U7_HUMAN,tr|A0A7I2YQU8|A0A7I2YQU8_HUMAN,tr|A0A7I2V651|A0A7I2V651_HUMAN,tr|A0A7I2V326|A0A7I2V326_HUMAN,tr|A0A7I2YQN9|A0A7I2YQN9_HUMAN" 7 1883.9225 1.38 72690 22541 2 1883.924223 942.9685 Ras GTPase-activating protein-binding protein 1 OS=Homo sapiens OX=9606 GN=G3BP1 PE=1 SV=1 4.03 3636.5 - 2.05E+06 - - - 0.9225 - 3.281 0.661 - 721.5 1 2 0 0.0017 18 0 0 0 7.60E+07 5.49E+07 - - - 6.8437 1 221125_WJC_METTL3_EV_vs_WT_F05.22542.22542.4 3.65E-10 21/192 K.STEEQLEEQQQQEEEVEEVEVEQVQVEADAQEK.A sp|Q8N5Z5|KCD17_HUMAN 1 3901.7349 6.68 72691 22542 4 3901.738601 976.441 BTB\POZ domain-containing protein KCTD17 OS=Homo sapiens OX=9606 GN=KCTD17 PE=1 SV=3 3.5 3636.6 - 526831 - - - 0.9562 - 4.291 0.676 - 300.4 1 2 0 0.0037 33 0 0 0 6.43E+06 9.63E+05 - - - 5.5459 0.9997 221125_WJC_METTL3_EV_vs_WT_F05.22545.22545.3 0.000156 Nov-76 K.EALKEFDFLVTSEEGDNESR.S sp|O43815|STRN_HUMAN 1 2314.0601 1.19 72694 22545 3 2314.065681 772.3606 Striatin OS=Homo sapiens OX=9606 GN=STRN PE=1 SV=4 4 3637 - 189234 - - - 2.4113 - 2.523 0.541 - 159.7 1 2 1 0.0056 20 0 0 0 1.65E+06 1.38E+06 - - - 6.8152 0.9998 221125_WJC_METTL3_EV_vs_WT_F05.22546.22546.3 1.37E-05 Aug-76 K.EALK[136.11]EFDFLVTSEEGDNESR[166.11].S sp|O43815|STRN_HUMAN 1 2332.0826 1.19 72695 22546 3 2332.087578 778.3681 Striatin OS=Homo sapiens OX=9606 GN=STRN PE=1 SV=4 4 3637.1 - 111841 - - - 2.147 - 2.033 0.593 - 64.2 1 2 1 0.005 20 0 0 0 1.65E+06 1.38E+06 - - - 6.8713 0.9999 221125_WJC_METTL3_EV_vs_WT_F05.22551.22551.3 9.11E-10 18/64 K.AAIDWFDGK[136.11]EFSGNPIK[136.11].V "sp|P35637|FUS_HUMAN,tr|H3BPE7|H3BPE7_HUMAN" 2 1909.9545 7.11 72698 22551 3 1909.959039 637.6588 RNA-binding protein FUS OS=Homo sapiens OX=9606 GN=FUS PE=1 SV=1 4.56 3637.8 - 394719 - - - 2.3692 - 3.788 0.537 - 529.1 1 2 1 0.0045 17 0 0 0 7.62E+07 1.07E+07 - - - 7.8904 0.9999 221125_WJC_METTL3_EV_vs_WT_F05.22554.22554.4 2.69E-06 10/174 R.TTGIVMDSGDGVTHTVPIYEGYALPHAILR.L "sp|P63261|ACTG_HUMAN,sp|P60709|ACTB_HUMAN,tr|A0A804GS07|A0A804GS07_HUMAN,tr|I3L3I0|I3L3I0_HUMAN,tr|E7EVS6|E7EVS6_HUMAN,tr|A0A6Q8PFE4|A0A6Q8PFE4_HUMAN,tr|I3L1U9|I3L1U9_HUMAN,tr|A0A2R8YEA7|A0A2R8YEA7_HUMAN,tr|A0A2R8Y793|A0A2R8Y793_HUMAN,tr|I3L4N8|I3L4N8_HUMAN" 10 3182.607 0.98 72701 22554 4 3182.617872 796.659 "Actin, cytoplasmic 2 OS=Homo sapiens OX=9606 GN=ACTG1 PE=1 SV=1" 5.2 3638.2 - 191635 - - - 3.4051 - 2.083 0.531 - 32.9 1 2 0 0.0108 30 0 0 0 8.02E+06 8.20E+06 - - - 4.0694 1 221125_WJC_METTL3_EV_vs_WT_F05.22559.22559.3 1.17E-06 Dec-76 R.SASSTSSLFSSSSQLFPPSR[166.11].L "sp|Q8TB72|PUM2_HUMAN,tr|A0A0C4DG68|A0A0C4DG68_HUMAN" 2 2068.9941 1.45 72705 22559 3 2068.998626 690.672 Pumilio homolog 2 OS=Homo sapiens OX=9606 GN=PUM2 PE=1 SV=2 9.47 3638.8 - 222150 - - - 2.1953 - 2.822 0.592 - 108.9 1 2 0 0.0045 20 0 0 0 5.03E+06 3.46E+06 - - - 7.6558 1 221125_WJC_METTL3_EV_vs_WT_F05.22562.22562.3 7.05E-09 Nov-68 R.DGIDDESYGQIFKPIISK.V sp|Q92769|HDAC2_HUMAN 1 2024.0102 1.76 72708 22562 3 2024.013041 675.6774 Histone deacetylase 2 OS=Homo sapiens OX=9606 GN=HDAC2 PE=1 SV=2 4.23 3639.2 - 157854 - - - 1.3854 - 2.553 0.595 - 129.2 1 2 0 0.0028 18 0 0 0 8.49E+06 4.81E+06 - - - 7.5068 0.9998 221125_WJC_METTL3_EV_vs_WT_F05.22567.22567.3 7.30E-05 Aug-68 R.DGIDDESYGQIFK[136.11]PIISK[136.11].V sp|Q92769|HDAC2_HUMAN 1 2040.0386 1.76 72711 22567 3 2040.040889 681.0202 Histone deacetylase 2 OS=Homo sapiens OX=9606 GN=HDAC2 PE=1 SV=2 4.23 3639.9 - 171553 - - - 1.1039 - 1.91 0.397 - 76.4 1 2 0 0.0023 18 0 0 0 8.47E+06 4.81E+06 - - - 4.5769 1 221125_WJC_METTL3_EV_vs_WT_F05.22570.22570.3 2.50E-08 13/64 K.HNQLPLVIEFTEQTAPK.L "sp|P07237|PDIA1_HUMAN,tr|A0A7P0TA97|A0A7P0TA97_HUMAN,tr|A0A7P0T8C0|A0A7P0T8C0_HUMAN,tr|H7BZ94|H7BZ94_HUMAN,tr|A0A7P0TA71|A0A7P0TA71_HUMAN,tr|I3L4M2|I3L4M2_HUMAN,tr|A0A7P0T9D6|A0A7P0T9D6_HUMAN,tr|A0A7P0T9K9|A0A7P0T9K9_HUMAN,tr|H0Y3Z3|H0Y3Z3_HUMAN,tr|A0A7P0TA35|A0A7P0TA35_HUMAN,tr|I3L514|I3L514_HUMAN,tr|A0A7P0TB26|A0A7P0TB26_HUMAN,tr|A0A7P0T9U6|A0A7P0T9U6_HUMAN,tr|I3L3P5|I3L3P5_HUMAN,tr|A0A7P0T8X1|A0A7P0T8X1_HUMAN" 15 1964.0367 1.57 72714 22570 3 1964.040109 655.6862 Protein disulfide-isomerase OS=Homo sapiens OX=9606 GN=P4HB PE=1 SV=3 5.4 3640.3 - 120006 - - - 1.722 - 2.818 0.652 - 233.8 1 2 0 0.0034 17 0 0 0 6.36E+06 4.04E+06 - - - 8.4255 1 221125_WJC_METTL3_EV_vs_WT_F05.22573.22573.3 5.16E-09 14/76 R.SASSTSSLFSSSSQLFPPSR.L "sp|Q8TB72|PUM2_HUMAN,tr|A0A0C4DG68|A0A0C4DG68_HUMAN" 2 2058.9858 1.5 72716 22573 3 2058.990429 687.3359 Pumilio homolog 2 OS=Homo sapiens OX=9606 GN=PUM2 PE=1 SV=2 9.47 3640.7 - 369518 - - - 2.2414 - 3.051 0.654 - 165.6 1 2 0 0.0046 20 0 0 0 6.48E+06 4.32E+06 - - - 8.5363 0.9975 221125_WJC_METTL3_EV_vs_WT_F05.22576.22576.3 0.00529 Jun-64 K.HNQLPLVIEFTEQTAPK[136.11].L "sp|P07237|PDIA1_HUMAN,tr|A0A7P0TA97|A0A7P0TA97_HUMAN,tr|A0A7P0T8C0|A0A7P0T8C0_HUMAN,tr|H7BZ94|H7BZ94_HUMAN,tr|A0A7P0TA71|A0A7P0TA71_HUMAN,tr|I3L4M2|I3L4M2_HUMAN,tr|A0A7P0T9D6|A0A7P0T9D6_HUMAN,tr|A0A7P0T9K9|A0A7P0T9K9_HUMAN,tr|H0Y3Z3|H0Y3Z3_HUMAN,tr|A0A7P0TA35|A0A7P0TA35_HUMAN,tr|I3L514|I3L514_HUMAN,tr|A0A7P0TB26|A0A7P0TB26_HUMAN,tr|A0A7P0T9U6|A0A7P0T9U6_HUMAN,tr|I3L3P5|I3L3P5_HUMAN,tr|A0A7P0T8X1|A0A7P0T8X1_HUMAN" 15 1972.0509 1.62 72718 22576 3 1972.056 658.3576 Protein disulfide-isomerase OS=Homo sapiens OX=9606 GN=P4HB PE=1 SV=3 5.4 3641 - 99247.3 - - - 2.5724 - 1.364 0.366 - 50.5 1 2 0 0.0051 17 0 0 0 6.67E+06 4.10E+06 - - - 3.4033 0.998 221125_WJC_METTL3_EV_vs_WT_F05.22597.22597.3 0.0191 Jun-56 K.DGQWFTDWDAVPHSR[166.11].H sp|Q08J23|NSUN2_HUMAN 1 1825.8048 0.84 72733 22597 3 1825.80946 609.6089 RNA cytosine C(5)-methyltransferase NSUN2 OS=Homo sapiens OX=9606 GN=NSUN2 PE=1 SV=2 4.41 3643.8 - 74872.5 - - - 2.5704 - 1.144 0.418 - 27.6 1 2 0 0.0047 15 0 0 0 1.35E+06 1.60E+06 - - - 3.55 1 221125_WJC_METTL3_EV_vs_WT_F05.22599.22599.3 2.18E-08 19/76 K.RIQEIIEQLDVTTSEYEKEK.L "sp|P10809|CH60_HUMAN,tr|A0A7I2V2X6|A0A7I2V2X6_HUMAN,tr|A0A7I2YQK6|A0A7I2YQK6_HUMAN,tr|A0A7I2V599|A0A7I2V599_HUMAN" 4 2450.2541 1.33 72734 22599 3 2450.261956 817.7586 "60 kDa heat shock protein, mitochondrial OS=Homo sapiens OX=9606 GN=HSPD1 PE=1 SV=2" 4.42 3644.1 - 269882 - - - 3.2266 - 3.72 0.626 - 534.7 1 2 1 0.0079 20 0 0 0 2.87E+07 2.16E+07 - - - 8.7042 0.9996 221125_WJC_METTL3_EV_vs_WT_F05.22601.22601.4 2.02E-05 13/114 K.RIQEIIEQLDVTTSEYEKEK.L "sp|P10809|CH60_HUMAN,tr|A0A7I2V2X6|A0A7I2V2X6_HUMAN,tr|A0A7I2YQK6|A0A7I2YQK6_HUMAN,tr|A0A7I2V599|A0A7I2V599_HUMAN" 4 2450.2541 1.28 72735 22601 4 2450.262314 613.5708 "60 kDa heat shock protein, mitochondrial OS=Homo sapiens OX=9606 GN=HSPD1 PE=1 SV=2" 4.42 3644.3 - 262447 - - - 3.3727 - 2.264 0.539 - 68.2 1 2 1 0.0083 20 0 0 0 1.57E+07 1.22E+07 - - - 4.1884 0.9988 221125_WJC_METTL3_EV_vs_WT_F05.22602.22602.4 3.39E-06 9/114 K.R[166.11]IQEIIEQLDVTTSEYEK[136.11]EK[136.11].L "sp|P10809|CH60_HUMAN,tr|A0A7I2V2X6|A0A7I2V2X6_HUMAN,tr|A0A7I2YQK6|A0A7I2YQK6_HUMAN,tr|A0A7I2V599|A0A7I2V599_HUMAN" 4 2476.2907 1.28 72736 22602 4 2476.301359 620.08 "60 kDa heat shock protein, mitochondrial OS=Homo sapiens OX=9606 GN=HSPD1 PE=1 SV=2" 4.42 3644.4 - 234640 - - - 4.2963 - 1.776 0.513 - 45.5 1 2 1 0.0106 20 0 0 0 1.56E+07 1.22E+07 - - - 3.8802 1 221125_WJC_METTL3_EV_vs_WT_F05.22603.22603.3 2.98E-15 17/116 R.QTAEESGITNSASSTLLSEYNVTNNSVALR.T sp|Q99459|CDC5L_HUMAN 1 3155.5218 1.33 72737 22603 3 3155.525369 1052.8479 Cell division cycle 5-like protein OS=Homo sapiens OX=9606 GN=CDC5L PE=1 SV=2 4.25 3644.5 - 263710 - - - 1.1168 - 3.717 0.731 - 191.9 1 2 0 0.0035 30 0 0 0 1.44E+07 1.09E+07 - - - 9.7095 0.9959 221125_WJC_METTL3_EV_vs_WT_F05.22604.22604.4 0.00046 11/120 R.LNEELK[136.11]VDEETQEVLENLK[136.11]DR[166.11].W "sp|Q9BRK5|CAB45_HUMAN,tr|A0A5F9UJX7|A0A5F9UJX7_HUMAN,tr|A0A5F9UP49|A0A5F9UP49_HUMAN" 3 2568.3129 2.59 72738 22604 4 2568.322057 643.0855 45 kDa calcium-binding protein OS=Homo sapiens OX=9606 GN=SDF4 PE=1 SV=1 4.17 3644.7 - 220760 - - - 3.5607 - 2.549 0.37 - 83.3 1 2 2 0.0091 21 0 0 0 8.53E+06 3.30E+06 - - - 2.7533 0.999 221125_WJC_METTL3_EV_vs_WT_F05.22610.22610.4 2.71E-05 16/120 R.LNEELKVDEETQEVLENLKDR.W "sp|Q9BRK5|CAB45_HUMAN,tr|A0A5F9UJX7|A0A5F9UJX7_HUMAN,tr|A0A5F9UP49|A0A5F9UP49_HUMAN" 3 2542.2762 2.59 72742 22610 4 2542.287129 636.5763 45 kDa calcium-binding protein OS=Homo sapiens OX=9606 GN=SDF4 PE=1 SV=1 4.17 3645.5 - 452611 - - - 4.2824 - 3.333 0.507 - 230.2 1 2 2 0.0109 21 0 0 0 8.56E+06 3.30E+06 - - - 4.034 1 221125_WJC_METTL3_EV_vs_WT_F05.22615.22615.3 1.08E-09 13/100 R.YAQPATATAATAAAAAAAAYSDGYGR.V "sp|O43251|RFOX2_HUMAN,tr|B0QYV1|B0QYV1_HUMAN,tr|A0A0G2JRD1|A0A0G2JRD1_HUMAN,tr|A0A0G2JRA5|A0A0G2JRA5_HUMAN,tr|S4R3K7|S4R3K7_HUMAN" 5 2431.1404 1.8 72747 22615 3 2431.140495 811.3874 RNA binding protein fox-1 homolog 2 OS=Homo sapiens OX=9606 GN=RBFOX2 PE=1 SV=3 5.83 3646.2 - 124949 - - - 0.0321 - 3.089 0.674 - 179.2 1 2 0 0.0001 26 0 0 0 6.49E+06 3.62E+06 - - - 8.6492 1 221125_WJC_METTL3_EV_vs_WT_F05.22618.22618.3 7.91E-06 14/60 K.K[136.11]VSQEILELLNTTTAK[136.11].E "sp|Q86U44|MTA70_HUMAN,tr|H0YFV6|H0YFV6_HUMAN" 2 1803.0324 -1 72749 22618 3 1803.037807 602.0181 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 6.14 3646.6 - 270130 - - - 2.9822 - 3.374 0.668 - 424.7 1 2 0 0.0054 16 0 0 0 0.00E+00 0.00E+00 - - - 9.1064 1 221125_WJC_METTL3_EV_vs_WT_F05.22623.22623.3 4.05E-09 28/76 K.R[166.11]IQEIIEQLDVTTSEYEK[136.11]EK[136.11].L "sp|P10809|CH60_HUMAN,tr|A0A7I2V2X6|A0A7I2V2X6_HUMAN,tr|A0A7I2YQK6|A0A7I2YQK6_HUMAN,tr|A0A7I2V599|A0A7I2V599_HUMAN" 4 2476.2907 1.38 72752 22623 3 2476.295981 826.4375 "60 kDa heat shock protein, mitochondrial OS=Homo sapiens OX=9606 GN=HSPD1 PE=1 SV=2" 4.42 3647.2 - 589815 - - - 2.1245 - 4.689 0.672 - 1277.2 1 2 1 0.0053 20 0 0 0 2.86E+07 2.08E+07 - - - 9.7794 0.9998 221125_WJC_METTL3_EV_vs_WT_F05.22626.22626.2 6.82E-05 Jun-38 R.SASSTSSLFSSSSQLFPPSR.L "sp|Q8TB72|PUM2_HUMAN,tr|A0A0C4DG68|A0A0C4DG68_HUMAN" 2 2058.9858 4.99 72755 22626 2 2058.984447 1030.5002 Pumilio homolog 2 OS=Homo sapiens OX=9606 GN=PUM2 PE=1 SV=2 9.47 3647.6 - 52891.6 - - - -0.6639 - 1.518 0.559 - 50.3 1 2 0 -0.0014 20 0 0 0 3.89E+06 7.80E+05 - - - 4.1955 1 221125_WJC_METTL3_EV_vs_WT_F05.22632.22632.3 1.49E-16 22/116 R.QTAEESGITNSASSTLLSEYNVTNNSVALR[166.11].T sp|Q99459|CDC5L_HUMAN 1 3165.5301 1.33 72758 22632 3 3165.536287 1056.184 Cell division cycle 5-like protein OS=Homo sapiens OX=9606 GN=CDC5L PE=1 SV=2 4.25 3648.4 - 423380 - - - 1.9498 - 4.371 0.762 - 389 1 2 0 0.0062 30 0 0 0 1.44E+07 1.09E+07 - - - 10.4273 0.9896 221125_WJC_METTL3_EV_vs_WT_F05.22634.22634.3 0.0298 May-56 R.DHADSNIVIMLVGNK.S "sp|Q15907|RB11B_HUMAN,sp|P62491|RB11A_HUMAN,tr|B4DQU5|B4DQU5_HUMAN,tr|H3BMH2|H3BMH2_HUMAN,tr|H3BSC1|H3BSC1_HUMAN" 5 1624.8243 1.67 72760 22634 3 1624.828203 542.6154 Ras-related protein Rab-11B OS=Homo sapiens OX=9606 GN=RAB11B PE=1 SV=4 5.21 3648.7 - 64924 - - - 2.4076 - 1.138 0.312 - 28.6 1 2 0 0.0039 15 0 0 0 5.34E+06 3.20E+06 - - - 2.3547 0.9962 221125_WJC_METTL3_EV_vs_WT_F05.22647.22647.4 0.023 5/150 R.VAQNLVGPDNVHVALSLVEYKPELQK.A sp|O95347|SMC2_HUMAN 1 2859.5494 1.08 72766 22647 4 2859.55516 715.8946 Structural maintenance of chromosomes protein 2 OS=Homo sapiens OX=9606 GN=SMC2 PE=1 SV=2 5.44 3650.7 - 149880 - - - 1.9989 - 1.328 0.273 - 10.3 1 2 0 0.0057 26 0 0 0 3.98E+06 3.69E+06 - - - 1.6901 0.9855 221125_WJC_METTL3_EV_vs_WT_F05.22651.22651.3 4.38E-06 Nov-96 K.QYNGVPLDGR[166.11]PMNIQLVTSQIDAQR[166.11].R "sp|Q86V81|THOC4_HUMAN,tr|E9PB61|E9PB61_HUMAN" 2 2832.4456 1.46 72768 22651 3 2833.435794 945.1558 THO complex subunit 4 OS=Homo sapiens OX=9606 GN=ALYREF PE=1 SV=3 5.96 3651.3 - 238974 - - - 349.6071 - 2.012 0.56 - 67.6 1 2 0 0.9902 25 0 0 0 5.24E+06 3.58E+06 - - - 6.1176 0.9997 221125_WJC_METTL3_EV_vs_WT_F05.22652.22652.2 0.000374 Jul-36 R.DNLTLWTSDQQDEEAGEGN.- sp|Q04917|1433F_HUMAN 1 2120.8771 - 72769 22652 2 2120.873858 1061.4458 14-3-3 protein eta OS=Homo sapiens OX=9606 GN=YWHAH PE=1 SV=4 3.29 3651.4 - 113439 - - - -1.5055 - 1.375 0.57 - 102.4 1 2 0 -0.0032 19 0 0 0 - - - - - 4.033 0.9295 221125_WJC_METTL3_EV_vs_WT_F05.22656.22656.3 0.000218 Sep-96 K.QYNGVPLDGRPMNIQLVTSQIDAQR.R "sp|Q86V81|THOC4_HUMAN,tr|E9PB61|E9PB61_HUMAN" 2 2812.429 1.26 72771 22656 3 2813.4272 938.4836 THO complex subunit 4 OS=Homo sapiens OX=9606 GN=ALYREF PE=1 SV=3 5.96 3651.9 - 221153 - - - 354.9206 - 1.535 0.334 - 47.2 1 2 0 0.9982 25 0 0 0 5.24E+06 4.16E+06 - - - 2.9732 0.9999 221125_WJC_METTL3_EV_vs_WT_F05.22659.22659.3 3.48E-07 18/80 K.QC[160.03]ANLQNAIADAEQRGELALK.D "sp|P13647|K2C5_HUMAN,tr|H0YI76|H0YI76_HUMAN" 2 2312.1543 1215.1 72774 22659 3 2312.156707 771.7254 "Keratin, type II cytoskeletal 5 OS=Homo sapiens OX=9606 GN=KRT5 PE=1 SV=3" 4.68 3652.3 - 365072 - - - 1.044 - 3.558 0.59 - 371.3 1 2 1 0.0024 21 0 0 0 3.17E+07 2.61E+04 - - - 8.1601 1 221125_WJC_METTL3_EV_vs_WT_F05.22660.22660.3 1.18E-10 14/72 R.GSLESIAEHVDASLSGSER.S "sp|Q5VT06|CE350_HUMAN,tr|H0Y7F7|H0Y7F7_HUMAN" 2 1942.9232 4.39 72775 22660 3 1942.924059 648.6483 Centrosome-associated protein 350 OS=Homo sapiens OX=9606 GN=CEP350 PE=1 SV=1 4.4 3652.4 - 121196 - - - 0.4354 - 2.994 0.614 - 268.8 1 2 0 0.0008 19 0 0 0 2.36E+06 5.38E+05 - - - 8.0794 0.9616 221125_WJC_METTL3_EV_vs_WT_F05.22676.22676.3 0.0142 13/68 R.K[136.11]IELFGR[166.11]PHNVQPNWITL.G sp|Q86U44|MTA70_HUMAN 1 2179.2021 0 72784 22676 3 2179.204356 727.408 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 8.75 3654.6 - 1.40E+06 - - - 1.0293 - 2.041 0.342 - 145.8 1 1 0 0.0022 18 0 0 0 1.41E+05 6.18E+07 - - - 4.1289 1 221125_WJC_METTL3_EV_vs_WT_F05.22677.22677.3 4.71E-11 18/64 K.DKNEQAFEEVFQNANFR.S "sp|P27694|RFA1_HUMAN,tr|I3L4R8|I3L4R8_HUMAN" 2 2084.9552 1.17 72785 22677 3 2084.952747 695.9923 Replication protein A 70 kDa DNA-binding subunit OS=Homo sapiens OX=9606 GN=RPA1 PE=1 SV=2 4.41 3654.7 - 325475 - - - -1.1679 - 3.318 0.667 - 455.3 1 2 1 -0.0024 17 0 0 0 2.47E+07 2.11E+07 - - - 9.0057 0.9965 221125_WJC_METTL3_EV_vs_WT_F05.22683.22683.3 2.49E-06 9/120 L.GGPGGFGPGGYPGGIHEVSVNQSLLQPLNVK.V sp|P35908|K22E_HUMAN 1 3031.5516 999 72789 22683 3 3031.554034 1011.5245 "Keratin, type II cytoskeletal 2 epidermal OS=Homo sapiens OX=9606 GN=KRT2 PE=1 SV=2" 6.75 3655.7 - 196102 - - - 0.8131 - 2.161 0.545 - 38.3 1 1 0 0.0025 31 0 0 0 4.40E+06 0.00E+00 - - - 6.3883 0.9748 221125_WJC_METTL3_EV_vs_WT_F05.22696.22696.3 0.0965 May-64 K.SLDKEISEAFTSTGFDR.H "sp|Q9BXK5|B2L13_HUMAN,tr|A0A087WX97|A0A087WX97_HUMAN,tr|A0A087WTL4|A0A087WTL4_HUMAN,tr|E9PDD6|E9PDD6_HUMAN" 4 1901.9007 2.54 72796 22696 3 1901.903578 634.9742 Bcl-2-like protein 13 OS=Homo sapiens OX=9606 GN=BCL2L13 PE=1 SV=1 4.32 3657.3 - 110848 - - - 1.5201 - 1.237 0.298 - 30.2 1 2 1 0.0029 17 0 0 0 2.10E+06 8.25E+05 - - - 2.3989 1 221125_WJC_METTL3_EV_vs_WT_F05.22698.22698.2 1.24E-07 26-Oct K.LISWYDNEFGYSNR[166.11].V "sp|P04406|G3P_HUMAN,tr|E7EUT5|E7EUT5_HUMAN" 2 1772.8034 1.1 72798 22698 2 1772.806682 887.409 Glyceraldehyde-3-phosphate dehydrogenase OS=Homo sapiens OX=9606 GN=GAPDH PE=1 SV=3 4.37 3657.5 - 72347.3 - - - 1.8682 - 2.275 0.676 - 333.5 1 2 0 0.0033 14 0 0 0 1.69E+07 1.54E+07 - - - 6.0956 0.9998 221125_WJC_METTL3_EV_vs_WT_F05.22705.22705.2 0.000229 Jun-38 R.SASSASSLFSPSSTLFSSSR.L "sp|Q14671|PUM1_HUMAN,tr|Q5T1Z8|Q5T1Z8_HUMAN,tr|H0YDK8|H0YDK8_HUMAN,tr|H0YEH2|H0YEH2_HUMAN,tr|Q5T1Z4|Q5T1Z4_HUMAN,tr|E9PR38|E9PR38_HUMAN" 6 1991.9436 2.43 72802 22705 2 1991.941632 996.9791 Pumilio homolog 1 OS=Homo sapiens OX=9606 GN=PUM1 PE=1 SV=3 9.47 3658.4 - 122020 - - - -0.995 - 1.741 0.52 - 59.8 1 2 0 -0.002 20 0 0 0 9.27E+06 3.82E+06 - - - 4.2443 1 221125_WJC_METTL3_EV_vs_WT_F05.22707.22707.3 9.60E-12 17/84 R.LDQVIHSNPAGIQQALAQLSSR.Q sp|P48634|PRC2A_HUMAN 1 2345.2452 2.07 72804 22707 3 2345.24553 782.7557 Protein PRRC2A OS=Homo sapiens OX=9606 GN=PRRC2A PE=1 SV=3 6.74 3658.7 - 239498 - - - 0.159 - 3.848 0.645 - 312.1 1 2 0 0.0004 22 0 0 0 9.25E+06 4.48E+06 - - - 8.9258 1 221125_WJC_METTL3_EV_vs_WT_F05.22709.22709.3 1.06E-05 16/84 R.LDQVIHSNPAGIQQALAQLSSR[166.11].Q sp|P48634|PRC2A_HUMAN 1 2355.2534 2.07 72806 22709 3 2355.259419 786.0918 Protein PRRC2A OS=Homo sapiens OX=9606 GN=PRRC2A PE=1 SV=3 6.74 3658.9 - 131316 - - - 2.5441 - 3.079 0.597 - 316.6 1 2 0 0.006 22 0 0 0 9.28E+06 4.48E+06 - - - 7.8606 0.9995 221125_WJC_METTL3_EV_vs_WT_F05.22710.22710.2 0.00187 22-Jul K.DAGVIAGLNVLR[166.11].L "sp|P0DMV8|HS71A_HUMAN,sp|P34931|HS71L_HUMAN,sp|P0DMV9|HS71B_HUMAN,tr|Q53FA3|Q53FA3_HUMAN,tr|A0A0G2JIW1|A0A0G2JIW1_HUMAN" 5 1206.696 0.17 72807 22710 2 1206.696103 604.3553 Heat shock 70 kDa protein 1A OS=Homo sapiens OX=9606 GN=HSPA1A PE=1 SV=1 5.84 3659.1 - 107902 - - - 0.0928 - 1.776 0.348 - 200.6 1 2 0 0.0001 12 0 0 0 1.94E+06 1.17E+07 - - - 3.1225 1 221125_WJC_METTL3_EV_vs_WT_F05.22715.22715.3 3.69E-10 20/64 K.DK[136.11]NEQAFEEVFQNANFR[166.11].S "sp|P27694|RFA1_HUMAN,tr|I3L4R8|I3L4R8_HUMAN" 2 2102.9777 1.17 72810 22715 3 2102.979583 701.9998 Replication protein A 70 kDa DNA-binding subunit OS=Homo sapiens OX=9606 GN=RPA1 PE=1 SV=2 4.41 3659.7 - 1.08E+06 - - - 0.9182 - 3.784 0.615 - 591.5 1 2 1 0.0019 17 0 0 0 2.47E+07 2.11E+07 - - - 8.7581 1 221125_WJC_METTL3_EV_vs_WT_F05.22723.22723.3 1.53E-05 13/76 R.SASSASSLFSPSSTLFSSSR[166.11].L "sp|Q14671|PUM1_HUMAN,tr|Q5T1Z8|Q5T1Z8_HUMAN,tr|H0YDK8|H0YDK8_HUMAN,tr|H0YEH2|H0YEH2_HUMAN,tr|Q5T1Z4|Q5T1Z4_HUMAN,tr|E9PR38|E9PR38_HUMAN" 6 2001.9519 2.04 72816 22723 3 2001.953645 668.3246 Pumilio homolog 1 OS=Homo sapiens OX=9606 GN=PUM1 PE=1 SV=3 9.47 3660.8 - 201930 - - - 0.8796 - 2.695 0.531 - 147.7 1 2 0 0.0018 20 0 0 0 9.91E+06 4.86E+06 - - - 6.8648 0.9992 221125_WJC_METTL3_EV_vs_WT_F05.22724.22724.3 0.0192 May-52 K.LISWYDNEFGYSNR.V "sp|P04406|G3P_HUMAN,tr|E7EUT5|E7EUT5_HUMAN" 2 1762.7951 1.17 72817 22724 3 1762.795189 588.6056 Glyceraldehyde-3-phosphate dehydrogenase OS=Homo sapiens OX=9606 GN=GAPDH PE=1 SV=3 4.37 3661 - 227925 - - - 0.0505 - 1.152 0.405 - 27.2 1 2 0 0.0001 14 0 0 0 5.61E+06 4.82E+06 - - - 3.4314 0.9992 221125_WJC_METTL3_EV_vs_WT_F05.22725.22725.3 0.00113 Aug-52 K.LISWYDNEFGYSNR[166.11].V "sp|P04406|G3P_HUMAN,tr|E7EUT5|E7EUT5_HUMAN" 2 1772.8034 1.17 72818 22725 3 1772.803992 591.9417 Glyceraldehyde-3-phosphate dehydrogenase OS=Homo sapiens OX=9606 GN=GAPDH PE=1 SV=3 4.37 3661.1 - 201572 - - - 0.3509 - 1.65 0.321 - 84 1 2 0 0.0006 14 0 0 0 5.61E+06 4.82E+06 - - - 3.4495 1 221125_WJC_METTL3_EV_vs_WT_F05.22726.22726.2 3.13E-05 Dec-38 R.SASSASSLFSPSSTLFSSSR[166.11].L "sp|Q14671|PUM1_HUMAN,tr|Q5T1Z8|Q5T1Z8_HUMAN,tr|H0YDK8|H0YDK8_HUMAN,tr|H0YEH2|H0YEH2_HUMAN,tr|Q5T1Z4|Q5T1Z4_HUMAN,tr|E9PR38|E9PR38_HUMAN" 6 2001.9519 2.43 72819 22726 2 2001.950971 1001.9832 Pumilio homolog 1 OS=Homo sapiens OX=9606 GN=PUM1 PE=1 SV=3 9.47 3661.2 - 177020 - - - -0.4561 - 2.804 0.584 - 267.3 1 2 0 -0.0009 20 0 0 0 9.27E+06 3.82E+06 - - - 5.889 0.9747 221125_WJC_METTL3_EV_vs_WT_F05.22727.22727.4 0.513 6/144 R.VSQMLILTPFQGQGHGAQLLETVHR[166.11].Y sp|O14929|HAT1_HUMAN 1 2769.4624 0.37 72820 22727 4 2769.467628 693.3729 Histone acetyltransferase type B catalytic subunit OS=Homo sapiens OX=9606 GN=HAT1 PE=1 SV=1 6.89 3661.4 - 113996 - - - 1.8971 - 1.476 0.229 - 15.1 3 2 0 0.0053 25 0 0 0 1.84E+06 4.92E+06 - - - 0.978 1 221125_WJC_METTL3_EV_vs_WT_F05.22729.22729.3 1.09E-09 18/76 R.SASSASSLFSPSSTLFSSSR.L "sp|Q14671|PUM1_HUMAN,tr|Q5T1Z8|Q5T1Z8_HUMAN,tr|H0YDK8|H0YDK8_HUMAN,tr|H0YEH2|H0YEH2_HUMAN,tr|Q5T1Z4|Q5T1Z4_HUMAN,tr|E9PR38|E9PR38_HUMAN" 6 1991.9436 2.03 72821 22729 3 1991.946849 664.9885 Pumilio homolog 1 OS=Homo sapiens OX=9606 GN=PUM1 PE=1 SV=3 9.47 3661.6 - 568425 - - - 1.624 - 3.515 0.639 - 357.7 1 2 0 0.0032 20 0 0 0 9.91E+06 4.89E+06 - - - 8.7129 1 221125_WJC_METTL3_EV_vs_WT_F05.22731.22731.2 1.68E-08 14/26 K.LISWYDNEFGYSNR.V "sp|P04406|G3P_HUMAN,tr|E7EUT5|E7EUT5_HUMAN" 2 1762.7951 1.08 72822 22731 2 1762.796299 882.4048 Glyceraldehyde-3-phosphate dehydrogenase OS=Homo sapiens OX=9606 GN=GAPDH PE=1 SV=3 4.37 3661.8 - 793473 - - - 0.6802 - 2.817 0.711 - 800.7 1 2 0 0.0012 14 0 0 0 1.67E+07 1.54E+07 - - - 6.891 1 221125_WJC_METTL3_EV_vs_WT_F05.22735.22735.3 1.31E-08 13/84 R.R[166.11]GPFELEAFYSDPQGVPYPEAK[136.11].L "sp|Q92598|HS105_HUMAN,tr|A0A0A0MSM0|A0A0A0MSM0_HUMAN" 2 2514.2186 0.001 72826 22735 3 2514.22062 839.0801 Heat shock protein 105 kDa OS=Homo sapiens OX=9606 GN=HSPH1 PE=1 SV=1 4.41 3662.3 - 178610 - - - 0.7991 - 2.809 0.674 - 170.9 1 2 0 0.002 22 0 0 0 0.00E+00 2.76E+06 - - - 8.5025 1 221125_WJC_METTL3_EV_vs_WT_F05.22737.22737.4 0.000133 Oct-78 K.NTDLYHC[160.03]LLEHLQR.L sp|Q8WVV4|POF1B_HUMAN 1 1810.8785 33.32 72828 22737 4 1810.879121 453.7269 Protein POF1B OS=Homo sapiens OX=9606 GN=POF1B PE=1 SV=3 5.99 3662.6 - 63548.6 - - - 0.3694 - 2.064 0.508 - 88.9 1 2 0 0.0007 14 0 0 0 7.65E+05 2.30E+04 - - - 3.9112 1 221125_WJC_METTL3_EV_vs_WT_F05.22740.22740.3 1.50E-08 22/72 K.NMDPLNDNIATLLHQSSDK.F sp|P35579|MYH9_HUMAN 1 2125.011 1 72829 22740 3 2125.012002 709.3443 Myosin-9 OS=Homo sapiens OX=9606 GN=MYH9 PE=1 SV=4 4.41 3663 - 492529 - - - 0.4795 - 3.723 0.641 - 527.6 1 2 0 0.001 19 0 0 0 9.66E+06 9.67E+06 - - - 8.9158 1 221125_WJC_METTL3_EV_vs_WT_F05.22741.22741.3 1.50E-10 20/72 K.NMDPLNDNIATLLHQSSDK[136.11].F sp|P35579|MYH9_HUMAN 1 2133.0252 1 72830 22741 3 2133.024773 712.0157 Myosin-9 OS=Homo sapiens OX=9606 GN=MYH9 PE=1 SV=4 4.41 3663.1 - 510917 - - - -0.1922 - 3.84 0.697 - 497.9 1 2 0 -0.0004 19 0 0 0 9.66E+06 9.67E+06 - - - 9.6163 0.9972 221125_WJC_METTL3_EV_vs_WT_F05.22743.22743.3 0.0358 Sep-80 K.GYIWNYGAIPQTWEDPGHNDK.H "sp|Q15181|IPYR_HUMAN,tr|Q5SQT6|Q5SQT6_HUMAN" 2 2460.1135 0.73 72832 22743 3 2460.119471 821.0451 Inorganic pyrophosphatase OS=Homo sapiens OX=9606 GN=PPA1 PE=1 SV=2 4.54 3663.4 - 153579 - - - 2.4377 - 1.503 0.335 - 54.1 1 2 0 0.006 21 0 0 0 1.91E+06 2.63E+06 - - - 3.2501 1 221125_WJC_METTL3_EV_vs_WT_F05.22744.22744.3 3.33E-09 Oct-80 R.ENPSEEAQNLVEFTDEEGYGR.Y sp|Q12874|SF3A3_HUMAN 1 2412.0353 17.9 72833 22744 3 2412.035892 805.0191 Splicing factor 3A subunit 3 OS=Homo sapiens OX=9606 GN=SF3A3 PE=1 SV=1 3.77 3663.5 - 125997 - - - 0.2276 - 2.363 0.698 - 88.6 1 2 0 0.0006 21 0 0 0 2.48E+06 1.38E+05 - - - 8.3835 1 221125_WJC_METTL3_EV_vs_WT_F05.22747.22747.3 8.73E-12 25/72 K.R[166.11]EEEEFNTGPLSVLTQSVK[136.11].N "sp|P62316|SMD2_HUMAN,tr|K7ERG4|K7ERG4_HUMAN" 2 2180.108 1.66 72835 22747 3 2180.108046 727.7099 Small nuclear ribonucleoprotein Sm D2 OS=Homo sapiens OX=9606 GN=SNRPD2 PE=1 SV=1 4.49 3663.9 - 1.33E+06 - - - 0.022 - 3.92 0.696 - 1074 1 2 0 0 19 0 0 0 1.79E+08 1.07E+08 - - - 9.6559 1 221125_WJC_METTL3_EV_vs_WT_F05.22750.22750.3 1.81E-10 15/104 K.DTPTSHVPSGPLSSSATSPVLLPALPR.R "sp|Q9NSC2|SALL1_HUMAN,tr|H3BSM9|H3BSM9_HUMAN" 2 2683.4181 3.42 72837 22750 3 2683.428372 895.48 Sal-like protein 1 OS=Homo sapiens OX=9606 GN=SALL1 PE=1 SV=2 6.74 3664.2 - 185986 - - - 3.8298 - 2.808 0.695 - 152.1 1 2 0 0.0103 27 0 0 0 8.87E+06 2.59E+06 - - - 8.6611 1 221125_WJC_METTL3_EV_vs_WT_F05.22751.22751.3 1.22E-13 28/88 R.R[166.11]QLLAQQLGAESADSIGAVLNSK[136.11].D "sp|Q9HCE5|MET14_HUMAN,tr|A0A0D9SFW0|A0A0D9SFW0_HUMAN,tr|A0A0D9SF88|A0A0D9SF88_HUMAN" 3 2386.2935 0.001 72838 22751 3 2386.295449 796.4384 N6-adenosine-methyltransferase non-catalytic subunit OS=Homo sapiens OX=9606 GN=METTL14 PE=1 SV=2 6.07 3664.3 - 1.67E+06 - - - 0.8138 - 5.355 0.709 - 1321.2 1 2 0 0.0019 23 0 0 0 0.00E+00 1.94E+07 - - - 10.3807 0.9999 221125_WJC_METTL3_EV_vs_WT_F05.22752.22752.3 0.000163 Sep-80 K.GYIWNYGAIPQTWEDPGHNDK[136.11].H "sp|Q15181|IPYR_HUMAN,tr|Q5SQT6|Q5SQT6_HUMAN" 2 2468.1277 0.73 72839 22752 3 2468.1262 823.7165 Inorganic pyrophosphatase OS=Homo sapiens OX=9606 GN=PPA1 PE=1 SV=2 4.54 3664.5 - 224954 - - - -0.5972 - 1.837 0.501 - 59.5 1 2 0 -0.0015 21 0 0 0 1.91E+06 2.63E+06 - - - 5.5832 1 221125_WJC_METTL3_EV_vs_WT_F05.22755.22755.3 3.16E-18 23/72 K.REEEEFNTGPLSVLTQSVK.N "sp|P62316|SMD2_HUMAN,tr|K7ERG4|K7ERG4_HUMAN" 2 2162.0855 1.67 72841 22755 3 2162.08841 721.7025 Small nuclear ribonucleoprotein Sm D2 OS=Homo sapiens OX=9606 GN=SNRPD2 PE=1 SV=1 4.49 3664.8 - 2.25E+06 - - - 1.333 - 3.905 0.739 - 883.1 1 2 0 0.0029 19 0 0 0 1.79E+08 1.07E+08 - - - 10.1251 0.9998 221125_WJC_METTL3_EV_vs_WT_F05.22758.22758.4 1.64E-07 19/132 K.AKDIVPGDIVEIAVGDKVPADIR.L sp|P16615|AT2A2_HUMAN 1 2389.3217 1.74 72843 22758 4 2389.328754 598.3377 Sarcoplasmic\endoplasmic reticulum calcium ATPase 2 OS=Homo sapiens OX=9606 GN=ATP2A2 PE=1 SV=1 4.36 3665.2 - 246832 - - - 2.9623 - 2.711 0.57 - 174.7 1 2 2 0.0071 23 0 0 0 1.05E+07 6.03E+06 - - - 4.5084 0.9997 221125_WJC_METTL3_EV_vs_WT_F05.22761.22761.2 0.000115 26-Jul K.SFYPEEVSSMVLTK[136.11].M "sp|P11142|HSP7C_HUMAN,tr|E9PQQ4|E9PQQ4_HUMAN,tr|E9PKE3|E9PKE3_HUMAN,tr|E9PN89|E9PN89_HUMAN,tr|E9PLF4|E9PLF4_HUMAN,tr|E9PI65|E9PI65_HUMAN,tr|E9PK54|E9PK54_HUMAN,tr|E9PN25|E9PN25_HUMAN,tr|E9PPY6|E9PPY6_HUMAN,tr|E9PQK7|E9PQK7_HUMAN" 10 1623.7946 0.1 72846 22761 2 1623.792767 812.9046 Heat shock cognate 71 kDa protein OS=Homo sapiens OX=9606 GN=HSPA8 PE=1 SV=1 4.53 3665.6 - 130614 - - - -1.1048 - 1.57 0.491 - 94.6 1 2 0 -0.0018 14 0 0 0 3.09E+05 3.04E+06 - - - 3.7989 0.993 221125_WJC_METTL3_EV_vs_WT_F05.22771.22771.3 0.00556 Aug-68 K.ISSIQSIVPALEIANAHR.K "sp|P10809|CH60_HUMAN,tr|A0A7I2V2X6|A0A7I2V2X6_HUMAN,tr|A0A7I2YQK6|A0A7I2YQK6_HUMAN,tr|A0A7I2V599|A0A7I2V599_HUMAN,tr|A0A7I2YQ71|A0A7I2YQ71_HUMAN,tr|A0A7I2V5M1|A0A7I2V5M1_HUMAN,tr|A0A7I2V5K3|A0A7I2V5K3_HUMAN,tr|A0A7I2V369|A0A7I2V369_HUMAN" 8 1918.0636 1.38 72854 22771 3 1918.070688 640.3618 "60 kDa heat shock protein, mitochondrial OS=Homo sapiens OX=9606 GN=HSPD1 PE=1 SV=2" 6.75 3666.9 - 143536 - - - 3.6902 - 1.584 0.319 - 64.4 1 2 0 0.0071 18 0 0 0 6.59E+07 4.78E+07 - - - 3.2399 0.9998 221125_WJC_METTL3_EV_vs_WT_F05.22776.22776.3 3.83E-05 Oct-72 R.IGSFTIQNVFPQSDGDSSK[136.11].V "sp|O95757|HS74L_HUMAN,tr|D6RJ96|D6RJ96_HUMAN,tr|E9PDE8|E9PDE8_HUMAN" 3 2033.9786 0.22 72857 22776 3 2033.98327 679.0001 Heat shock 70 kDa protein 4L OS=Homo sapiens OX=9606 GN=HSPA4L PE=1 SV=3 4.21 3667.6 - 136017 - - - 2.3206 - 1.801 0.484 - 84.2 1 2 0 0.0047 19 0 0 0 7.96E+05 3.62E+06 - - - 5.3803 0.9999 221125_WJC_METTL3_EV_vs_WT_F05.22780.22780.3 0.000117 13/68 K.ISSIQSIVPALEIANAHR[166.11].K "sp|P10809|CH60_HUMAN,tr|A0A7I2V2X6|A0A7I2V2X6_HUMAN,tr|A0A7I2YQK6|A0A7I2YQK6_HUMAN,tr|A0A7I2V599|A0A7I2V599_HUMAN,tr|A0A7I2YQ71|A0A7I2YQ71_HUMAN,tr|A0A7I2V5M1|A0A7I2V5M1_HUMAN,tr|A0A7I2V5K3|A0A7I2V5K3_HUMAN,tr|A0A7I2V369|A0A7I2V369_HUMAN" 8 1928.0719 1.38 72861 22780 3 1928.073482 643.6979 "60 kDa heat shock protein, mitochondrial OS=Homo sapiens OX=9606 GN=HSPD1 PE=1 SV=2" 6.75 3668.1 - 116958 - - - 0.8309 - 2.35 0.465 - 209.8 1 2 0 0.0016 18 0 0 0 6.59E+07 4.78E+07 - - - 5.8514 0.9496 221125_WJC_METTL3_EV_vs_WT_F05.22782.22782.3 0.000545 Sep-76 L.HSASIPGILALDLC[160.03]PSDTNK[136.11].L "sp|Q9UMS4|PRP19_HUMAN,tr|F5GY56|F5GY56_HUMAN" 2 2116.0714 11.76 72863 22782 3 2116.079689 706.3644 Pre-mRNA-processing factor 19 OS=Homo sapiens OX=9606 GN=PRPF19 PE=1 SV=1 5.21 3668.4 - 90091.2 - - - 3.9148 - 2.149 0.466 - 68.4 1 1 0 0.0083 20 0 0 0 2.76E+07 2.35E+06 - - - 5.5891 0.9999 221125_WJC_METTL3_EV_vs_WT_F05.22787.22787.4 4.84E-08 19/132 K.AK[136.11]DIVPGDIVEIAVGDK[136.11]VPADIR[166.11].L sp|P16615|AT2A2_HUMAN 1 2415.3583 1.75 72866 22787 4 2415.361928 604.8469 Sarcoplasmic\endoplasmic reticulum calcium ATPase 2 OS=Homo sapiens OX=9606 GN=ATP2A2 PE=1 SV=1 4.36 3669 - 487987 - - - 1.483 - 3.573 0.518 - 181 1 2 2 0.0036 23 0 0 0 1.04E+07 5.95E+06 - - - 4.1462 0.9999 221125_WJC_METTL3_EV_vs_WT_F05.22796.22796.3 3.43E-06 9/104 K.DTPTSHVPSGPLSSSATSPVLLPALPR[166.11].R "sp|Q9NSC2|SALL1_HUMAN,tr|H3BSM9|H3BSM9_HUMAN" 2 2693.4264 3.42 72873 22796 3 2693.434458 898.8161 Sal-like protein 1 OS=Homo sapiens OX=9606 GN=SALL1 PE=1 SV=2 6.74 3670.3 - 205902 - - - 3.0047 - 2.274 0.581 - 46.4 1 2 0 0.0081 27 0 0 0 8.87E+06 2.59E+06 - - - 6.9054 1 221125_WJC_METTL3_EV_vs_WT_F05.22797.22797.3 9.32E-10 19/88 R.SALQSINEWAAQTTDGKLPEVTK.D "sp|P50454|SERPH_HUMAN,tr|E9PNX1|E9PNX1_HUMAN,tr|E9PPV6|E9PPV6_HUMAN,tr|E9PR70|E9PR70_HUMAN,tr|E9PMI5|E9PMI5_HUMAN,tr|E9PJH8|E9PJH8_HUMAN,tr|E9PK86|E9PK86_HUMAN" 7 2486.2653 1.74 72874 22797 3 2486.273063 829.7624 Serpin H1 OS=Homo sapiens OX=9606 GN=SERPINH1 PE=1 SV=2 4.68 3670.4 - 432098 - - - 3.1292 - 4.308 0.602 - 325.9 1 2 1 0.0078 23 0 0 0 2.52E+07 1.45E+07 - - - 8.6757 0.9998 221125_WJC_METTL3_EV_vs_WT_F05.22799.22799.3 9.45E-09 15/88 R.SALQSINEWAAQTTDGK[136.11]LPEVTK[136.11].D "sp|P50454|SERPH_HUMAN,tr|E9PNX1|E9PNX1_HUMAN,tr|E9PPV6|E9PPV6_HUMAN,tr|E9PR70|E9PR70_HUMAN,tr|E9PMI5|E9PMI5_HUMAN,tr|E9PJH8|E9PJH8_HUMAN,tr|E9PK86|E9PK86_HUMAN" 7 2502.2937 1.73 72876 22799 3 2502.301013 835.1052 Serpin H1 OS=Homo sapiens OX=9606 GN=SERPINH1 PE=1 SV=2 4.68 3670.6 - 304035 - - - 2.9293 - 3.59 0.6 - 200.1 1 2 1 0.0073 23 0 0 0 2.52E+07 1.45E+07 - - - 8.2259 0.9182 221125_WJC_METTL3_EV_vs_WT_F05.22800.22800.3 0.00229 6/112 R.LSVFQQGVDQGLSLSQEPQGNADASSLTR[166.11].S "sp|Q96BT3|CENPT_HUMAN,tr|H3BTR4|H3BTR4_HUMAN" 2 3041.4929 1.98 72877 22800 3 3042.490638 1014.8383 Centromere protein T OS=Homo sapiens OX=9606 GN=CENPT PE=1 SV=2 4.03 3670.8 - 73262.5 - - - 328.0287 - 1.415 0.342 - 18.2 1 2 0 0.9977 29 0 0 0 4.57E+06 2.30E+06 - - - 2.8752 0.9997 221125_WJC_METTL3_EV_vs_WT_F05.22805.22805.4 3.79E-07 19/126 K.DKGVLQEEEDVLVNVNLVDKER.A sp|O43290|SNUT1_HUMAN 1 2539.313 3.57 72880 22805 4 2539.319884 635.8355 U4\U6.U5 tri-snRNP-associated protein 1 OS=Homo sapiens OX=9606 GN=SART1 PE=1 SV=1 4.2 3671.5 - 277472 - - - 2.7259 - 3.72 0.504 - 363.2 1 2 2 0.0069 22 0 0 0 2.90E+06 8.11E+05 - - - 4.0408 0.9991 221125_WJC_METTL3_EV_vs_WT_F05.22808.22808.4 0.00205 8/132 R.SALQSINEWAAQTTDGKLPEVTK.D "sp|P50454|SERPH_HUMAN,tr|E9PNX1|E9PNX1_HUMAN,tr|E9PPV6|E9PPV6_HUMAN,tr|E9PR70|E9PR70_HUMAN,tr|E9PMI5|E9PMI5_HUMAN,tr|E9PJH8|E9PJH8_HUMAN,tr|E9PK86|E9PK86_HUMAN" 7 2486.2653 2.34 72883 22808 4 2486.269614 622.5736 Serpin H1 OS=Homo sapiens OX=9606 GN=SERPINH1 PE=1 SV=2 4.68 3671.9 - 114790 - - - 1.742 - 1.84 0.402 - 36.1 1 2 1 0.0043 23 0 0 0 2.13E+06 9.10E+05 - - - 2.9214 1 221125_WJC_METTL3_EV_vs_WT_F05.22819.22819.3 2.81E-07 18/64 R.REEAVQQMADALQYLQK.V "sp|A8K0Z3|WASH1_HUMAN,sp|C4AMC7|WASH3_HUMAN,sp|Q6VEQ5|WASH2_HUMAN" 3 2020.0048 0.65 72892 22819 3 2020.008627 674.3422 WASH complex subunit 1 OS=Homo sapiens OX=9606 GN=WASHC1 PE=1 SV=2 4.68 3673.3 - 272466 - - - 1.9069 - 3.469 0.621 - 474.8 1 2 0 0.0039 17 0 0 0 6.73E+06 1.03E+07 - - - 8.6049 0.9958 221125_WJC_METTL3_EV_vs_WT_F05.22820.22820.4 0.0298 7/132 R.SALQSINEWAAQTTDGK[136.11]LPEVTK[136.11].D "sp|P50454|SERPH_HUMAN,tr|E9PNX1|E9PNX1_HUMAN,tr|E9PPV6|E9PPV6_HUMAN,tr|E9PR70|E9PR70_HUMAN,tr|E9PMI5|E9PMI5_HUMAN,tr|E9PJH8|E9PJH8_HUMAN,tr|E9PK86|E9PK86_HUMAN" 7 2502.2937 2.4 72893 22820 4 2502.297578 626.5807 Serpin H1 OS=Homo sapiens OX=9606 GN=SERPINH1 PE=1 SV=2 4.68 3673.4 - 169649 - - - 1.5566 - 1.565 0.314 - 27.7 1 2 1 0.0039 23 0 0 0 2.13E+06 8.87E+05 - - - 2.1031 1 221125_WJC_METTL3_EV_vs_WT_F05.22822.22822.3 5.19E-08 13/76 K.FEAHPNDLYVEGLPENIPFR.S "sp|P78347|GTF2I_HUMAN,tr|A0A494C0Q7|A0A494C0Q7_HUMAN,tr|A0A494C1K3|A0A494C1K3_HUMAN" 3 2356.1488 1.82 72895 22822 3 2356.15591 786.3902 General transcription factor II-I OS=Homo sapiens OX=9606 GN=GTF2I PE=1 SV=2 4.4 3673.7 - 126887 - - - 3.0189 - 2.9 0.655 - 124.1 1 2 0 0.0071 20 0 0 0 1.07E+07 5.90E+06 - - - 8.4236 1 221125_WJC_METTL3_EV_vs_WT_F05.22830.22830.3 3.07E-10 18/112 R.LSVFQQGVDQGLSLSQEPQGNADASSLTR.S "sp|Q96BT3|CENPT_HUMAN,tr|H3BTR4|H3BTR4_HUMAN" 2 3031.4847 2 72899 22830 3 3031.487208 1011.5022 Centromere protein T OS=Homo sapiens OX=9606 GN=CENPT PE=1 SV=2 4.03 3674.8 - 345514 - - - 0.8369 - 3.477 0.686 - 177.3 1 2 0 0.0025 29 0 0 0 4.62E+06 2.30E+06 - - - 9.0545 1 221125_WJC_METTL3_EV_vs_WT_F05.22832.22832.3 2.70E-06 19/64 R.R[166.11]EEAVQQMADALQYLQK[136.11].V "sp|A8K0Z3|WASH1_HUMAN,sp|C4AMC7|WASH3_HUMAN,sp|Q6VEQ5|WASH2_HUMAN" 3 2038.0272 0.66 72901 22832 3 2038.026704 680.3497 WASH complex subunit 1 OS=Homo sapiens OX=9606 GN=WASHC1 PE=1 SV=2 4.68 3675 - 633860 - - - -0.2655 - 3.588 0.502 - 596.8 1 2 0 -0.0005 17 0 0 0 6.82E+06 1.03E+07 - - - 7.3642 1 221125_WJC_METTL3_EV_vs_WT_F05.22834.22834.3 2.40E-13 20/92 K.VEHEISEGNVATAAAAALASAATK.A sp|Q92922|SMRC1_HUMAN 1 2281.155 3.9 72903 22834 3 2281.166011 761.3923 SWI\SNF complex subunit SMARCC1 OS=Homo sapiens OX=9606 GN=SMARCC1 PE=1 SV=3 4.75 3675.3 - 242302 - - - 4.8252 - 4.49 0.687 - 548.1 1 2 0 0.011 24 0 0 0 2.53E+06 6.50E+05 - - - 9.6845 1 221125_WJC_METTL3_EV_vs_WT_F05.22838.22838.3 7.41E-08 18/76 K.GDVAEGDLIEHFSQFGTVEK.A sp|Q13151|ROA0_HUMAN 1 2177.0277 1.81 72905 22838 3 2177.029669 726.6832 Heterogeneous nuclear ribonucleoprotein A0 OS=Homo sapiens OX=9606 GN=HNRNPA0 PE=1 SV=1 4.17 3675.9 - 482814 - - - 0.9145 - 4.121 0.617 - 471.3 1 2 0 0.002 20 0 0 0 5.32E+06 2.94E+06 - - - 8.8539 1 221125_WJC_METTL3_EV_vs_WT_F05.22842.22842.3 2.01E-09 16/104 R.SLSFPILNPALSQPSQPSSPLPGSHGR.N "sp|Q8ND24|RN214_HUMAN,tr|E9PN76|E9PN76_HUMAN" 2 2770.4402 3.14 72909 22842 3 2770.434176 924.4874 RING finger protein 214 OS=Homo sapiens OX=9606 GN=RNF214 PE=1 SV=2 9.49 3676.4 - 192714 - - - -2.1845 - 2.964 0.654 - 193 1 2 0 -0.0061 27 0 0 0 3.82E+07 1.22E+07 - - - 8.3295 1 221125_WJC_METTL3_EV_vs_WT_F05.22847.22847.3 0.00629 17/60 K.K[136.11]VSQEILELLNTTTAK[136.11].E "sp|Q86U44|MTA70_HUMAN,tr|H0YFV6|H0YFV6_HUMAN" 2 1803.0324 0.03 72913 22847 3 1803.034201 602.0181 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 6.14 3677 - 565584 - - - 0.9822 - 3.786 0.633 - 588.3 1 2 0 0.0018 16 0 0 0 4.98E+05 1.78E+07 - - - 9.0128 1 221125_WJC_METTL3_EV_vs_WT_F05.22848.22848.3 3.39E-12 17/88 R.ESNTPAPSTQGLPDSWGIIAEPR.Q "sp|O14654|IRS4_HUMAN,tr|A0A804CF45|A0A804CF45_HUMAN" 2 2422.1765 1.28 72914 22848 3 2422.178324 808.3994 Insulin receptor substrate 4 OS=Homo sapiens OX=9606 GN=IRS4 PE=1 SV=1 4.14 3677.1 - 676878 - - - 0.7663 - 3.065 0.649 - 253.1 1 2 0 0.0019 23 0 0 0 5.04E+07 3.93E+07 - - - 8.4028 0.8979 221125_WJC_METTL3_EV_vs_WT_F05.22850.22850.4 0.0432 10/114 R.GFGFVTFDDHDPVDKIVLQK.Y "sp|P22626|ROA2_HUMAN,tr|A0A024RA28|A0A024RA28_HUMAN,tr|A0A7I2V4N1|A0A7I2V4N1_HUMAN,tr|A0A7I2V4I6|A0A7I2V4I6_HUMAN,tr|A0A087WUI2|A0A087WUI2_HUMAN,tr|A0A7I2V4S4|A0A7I2V4S4_HUMAN,tr|A0A7I2V323|A0A7I2V323_HUMAN,tr|A0A7I2V3P1|A0A7I2V3P1_HUMAN,tr|A0A7I2V3P7|A0A7I2V3P7_HUMAN" 9 2276.1477 12.69 72916 22850 4 2276.155727 570.0442 Heterogeneous nuclear ribonucleoproteins A2\B1 OS=Homo sapiens OX=9606 GN=HNRNPA2B1 PE=1 SV=2 4.56 3677.4 - 204705 - - - 3.5116 - 1.462 0.228 - 33.8 1 2 1 0.008 20 0 0 0 1.79E+06 1.41E+05 - - - 1.3353 0.9988 221125_WJC_METTL3_EV_vs_WT_F05.22854.22854.2 0.0955 14-Apr K.IPDWFLNR.Q "sp|P62269|RS18_HUMAN,tr|J3JS69|J3JS69_HUMAN" 2 1059.5502 0.95 72920 22854 2 1059.550879 530.7824 40S ribosomal protein S18 OS=Homo sapiens OX=9606 GN=RPS18 PE=1 SV=3 5.84 3677.9 - 79963.8 - - - 0.6739 - 1.149 0.387 - 55 1 2 0 0.0007 8 0 0 0 1.25E+06 1.32E+06 - - - 2.318 1 221125_WJC_METTL3_EV_vs_WT_F05.22857.22857.3 2.15E-11 20/88 R.ESNTPAPSTQGLPDSWGIIAEPR[166.11].Q "sp|O14654|IRS4_HUMAN,tr|A0A804CF45|A0A804CF45_HUMAN" 2 2432.1847 1.28 72921 22857 3 2432.188501 811.7355 Insulin receptor substrate 4 OS=Homo sapiens OX=9606 GN=IRS4 PE=1 SV=1 4.14 3678.3 - 1.66E+06 - - - 1.5472 - 3.274 0.698 - 389.6 1 2 0 0.0038 23 0 0 0 5.04E+07 3.93E+07 - - - 9.1033 1 221125_WJC_METTL3_EV_vs_WT_F05.22859.22859.3 2.54E-08 13/92 R.ISSTSHTQDVVYLQQQLQAYAMER[166.11].E "sp|Q15643|TRIPB_HUMAN,tr|H0YJ97|H0YJ97_HUMAN" 2 2805.3631 0.78 72923 22859 3 2805.364122 936.1283 Thyroid receptor-interacting protein 11 OS=Homo sapiens OX=9606 GN=TRIP11 PE=1 SV=3 5.32 3678.6 - 240972 - - - 0.3597 - 3.086 0.618 - 205.2 1 2 0 0.001 24 0 0 0 3.72E+06 4.77E+06 - - - 8.0471 1 221125_WJC_METTL3_EV_vs_WT_F05.22860.22860.3 7.04E-15 24/104 K.AAQYQVNQAAAAQAAATAAAMTQSAVK.S "sp|Q9NR56|MBNL1_HUMAN,tr|Q86VM6|Q86VM6_HUMAN,tr|A0A0A0MQX8|A0A0A0MQX8_HUMAN,tr|C9JP00|C9JP00_HUMAN" 4 2605.2918 1.51 72924 22860 3 2605.299706 869.4379 Muscleblind-like protein 1 OS=Homo sapiens OX=9606 GN=MBNL1 PE=1 SV=2 8.63 3678.7 - 222071 - - - 3.0158 - 5.027 0.728 - 806.9 1 2 0 0.0079 27 0 0 0 4.07E+06 2.69E+06 - - - 10.3694 1 221125_WJC_METTL3_EV_vs_WT_F05.22871.22871.2 2.32E-10 Oct-44 R.ESNTPAPSTQGLPDSWGIIAEPR[166.11].Q "sp|O14654|IRS4_HUMAN,tr|A0A804CF45|A0A804CF45_HUMAN" 2 2432.1847 1.27 72933 22871 2 2432.185872 1217.0996 Insulin receptor substrate 4 OS=Homo sapiens OX=9606 GN=IRS4 PE=1 SV=1 4.14 3680.1 - 194760 - - - 0.4662 - 2.623 0.6 - 133.2 1 2 0 0.0011 23 0 0 0 2.73E+06 2.15E+06 - - - 5.8431 1 221125_WJC_METTL3_EV_vs_WT_F05.22874.22874.2 6.38E-12 15/44 R.ESNTPAPSTQGLPDSWGIIAEPR.Q "sp|O14654|IRS4_HUMAN,tr|A0A804CF45|A0A804CF45_HUMAN" 2 2422.1765 1.27 72936 22874 2 2422.177188 1212.0955 Insulin receptor substrate 4 OS=Homo sapiens OX=9606 GN=IRS4 PE=1 SV=1 4.14 3680.5 - 195245 - - - 0.2973 - 2.897 0.706 - 370.1 1 2 0 0.0007 23 0 0 0 2.73E+06 2.15E+06 - - - 6.8704 0.9998 221125_WJC_METTL3_EV_vs_WT_F05.22878.22878.3 0.0432 Sep-88 R.DNLTLWTSDTQGDEAEAGEGGEN.- "sp|P63104|1433Z_HUMAN,tr|H0YB80|H0YB80_HUMAN,tr|B7Z2E6|B7Z2E6_HUMAN,tr|B0AZS6|B0AZS6_HUMAN" 4 2407.9888 - 72938 22878 3 2407.990143 803.6702 14-3-3 protein zeta\delta OS=Homo sapiens OX=9606 GN=YWHAZ PE=1 SV=1 3.26 3681 - 351317 - - - 0.5635 - 1.542 0.462 - 63.3 1 2 0 0.0014 23 0 0 0 - - - - - 4.7064 0.9955 221125_WJC_METTL3_EV_vs_WT_F05.22882.22882.3 4.73E-06 Sep-72 L.TLGNQLDGIHLLDPDVVAR[166.11].F sp|Q86U44|MTA70_HUMAN 1 2055.0988 0.02 72942 22882 3 2055.10239 686.0402 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 4.41 3681.6 - 238313 - - - 1.7357 - 2.037 0.573 - 40.7 1 1 0 0.0036 19 0 0 0 2.61E+04 1.35E+06 - - - 6.6754 0.9998 221125_WJC_METTL3_EV_vs_WT_F05.22883.22883.3 2.26E-05 Dec-76 K.FEAHPNDLYVEGLPENIPFR[166.11].S "sp|P78347|GTF2I_HUMAN,tr|A0A494C0Q7|A0A494C0Q7_HUMAN,tr|A0A494C1K3|A0A494C1K3_HUMAN" 3 2366.1571 1.78 72943 22883 3 2366.16762 789.7263 General transcription factor II-I OS=Homo sapiens OX=9606 GN=GTF2I PE=1 SV=2 4.4 3681.7 - 183641 - - - 4.46 - 2.81 0.578 - 92.5 1 2 0 0.0106 20 0 0 0 1.05E+07 5.90E+06 - - - 7.4877 0.9998 221125_WJC_METTL3_EV_vs_WT_F05.22884.22884.2 2.55E-05 Sep-44 R.DNLTLWTSDTQGDEAEAGEGGEN.- "sp|P63104|1433Z_HUMAN,tr|H0YB80|H0YB80_HUMAN,tr|B7Z2E6|B7Z2E6_HUMAN,tr|B0AZS6|B0AZS6_HUMAN" 4 2407.9888 - 72944 22884 2 2407.988936 1205.0017 14-3-3 protein zeta\delta OS=Homo sapiens OX=9606 GN=YWHAZ PE=1 SV=1 3.26 3681.8 - 138628 - - - 0.0623 - 1.843 0.527 - 146.7 1 2 0 0.0001 23 0 0 0 - - - - - 4.4365 1 221125_WJC_METTL3_EV_vs_WT_F05.22885.22885.3 1.05E-06 8/132 R.DSPAVSLSEPATQQASLDVEKPVGVAASLSDIPK.A "sp|Q14687|GSE1_HUMAN,tr|H7C3B5|H7C3B5_HUMAN" 2 3405.7515 4.08 72945 22885 3 3405.751769 1136.2578 Genetic suppressor element 1 OS=Homo sapiens OX=9606 GN=GSE1 PE=1 SV=3 4.11 3681.9 - 137154 - - - 0.0758 - 2.052 0.576 - 38.2 1 2 0 0.0003 34 0 0 0 3.31E+06 8.11E+05 - - - 6.6155 0.9998 221125_WJC_METTL3_EV_vs_WT_F05.22887.22887.2 1.22E-05 Jun-36 R.IGSFTIQNVFPQSDGDSSK[136.11].V "sp|O95757|HS74L_HUMAN,tr|D6RJ96|D6RJ96_HUMAN,tr|E9PDE8|E9PDE8_HUMAN" 3 2033.9786 0.01 72947 22887 2 2033.979094 1017.9966 Heat shock 70 kDa protein 4L OS=Homo sapiens OX=9606 GN=HSPA4L PE=1 SV=3 4.21 3682.2 - 90706.4 - - - 0.2675 - 1.601 0.549 - 53.7 1 2 0 0.0005 19 0 0 0 5.11E+04 3.64E+06 - - - 4.2528 0.9999 221125_WJC_METTL3_EV_vs_WT_F05.22898.22898.2 1.14E-07 24-Oct K.C[160.03]EFQDAYVLLSEK.K "sp|P10809|CH60_HUMAN,tr|A0A7I2V2X6|A0A7I2V2X6_HUMAN,tr|A0A7I2YQK6|A0A7I2YQK6_HUMAN,tr|A0A7I2V599|A0A7I2V599_HUMAN,tr|A0A7I2YQ71|A0A7I2YQ71_HUMAN,tr|A0A7I2V5M1|A0A7I2V5M1_HUMAN,tr|A0A7I2V5K3|A0A7I2V5K3_HUMAN,tr|A0A7I2V369|A0A7I2V369_HUMAN" 8 1600.7443 1.54 72954 22898 2 1600.746513 801.3794 "60 kDa heat shock protein, mitochondrial OS=Homo sapiens OX=9606 GN=HSPD1 PE=1 SV=2" 4.14 3683.7 - 172066 - - - 1.3762 - 2.204 0.61 - 320.6 1 2 0 0.0022 13 0 0 0 3.56E+06 2.31E+06 - - - 5.574 1 221125_WJC_METTL3_EV_vs_WT_F05.22899.22899.3 1.60E-08 18/92 R.ISSTSHTQDVVYLQQQLQAYAMER.E "sp|Q15643|TRIPB_HUMAN,tr|H0YJ97|H0YJ97_HUMAN" 2 2795.3548 0.78 72955 22899 3 2795.359647 932.7922 Thyroid receptor-interacting protein 11 OS=Homo sapiens OX=9606 GN=TRIP11 PE=1 SV=3 5.32 3683.8 - 245700 - - - 1.7186 - 3.962 0.649 - 443.3 1 2 0 0.0048 24 0 0 0 3.72E+06 4.77E+06 - - - 8.972 0.9998 221125_WJC_METTL3_EV_vs_WT_F05.22909.22909.4 9.68E-06 9/198 R.DSPAVSLSEPATQQASLDVEKPVGVAASLSDIPK.A "sp|Q14687|GSE1_HUMAN,tr|H7C3B5|H7C3B5_HUMAN" 2 3405.7515 6.5 72963 22909 4 3405.75991 852.4452 Genetic suppressor element 1 OS=Homo sapiens OX=9606 GN=GSE1 PE=1 SV=3 4.11 3685.2 - 133462 - - - 2.4661 - 2.062 0.44 - 29.5 1 2 0 0.0084 34 0 0 0 1.86E+06 2.86E+05 - - - 3.2692 1 221125_WJC_METTL3_EV_vs_WT_F05.22917.22917.3 1.15E-05 15/104 R.SLSFPILNPALSQPSQPSSPLPGSHGR[166.11].N "sp|Q8ND24|RN214_HUMAN,tr|E9PN76|E9PN76_HUMAN" 2 2780.4485 3.13 72969 22917 3 2780.452851 927.8234 RING finger protein 214 OS=Homo sapiens OX=9606 GN=RNF214 PE=1 SV=2 9.49 3686.3 - 292197 - - - 1.5656 - 3.011 0.583 - 160.7 1 2 0 0.0044 27 0 0 0 3.80E+07 1.22E+07 - - - 7.5746 0.9671 221125_WJC_METTL3_EV_vs_WT_F05.22920.22920.4 0.0165 6/138 K.QKVPPVLQVLHC[160.03]GDESMLDIGGER.G sp|Q9UJV9|DDX41_HUMAN 1 2676.3364 4.57 72972 22920 4 2676.348688 670.0914 Probable ATP-dependent RNA helicase DDX41 OS=Homo sapiens OX=9606 GN=DDX41 PE=1 SV=2 4.75 3686.7 - 64519.6 - - - 4.6074 - 1.23 0.326 - 16.3 1 2 1 0.0123 24 0 0 0 4.28E+05 9.35E+04 - - - 2.1265 1 221125_WJC_METTL3_EV_vs_WT_F05.22925.22925.4 3.29E-05 11/126 R.LTLYDIAHTPGVAADLSHIETK.A sp|P40926|MDHM_HUMAN 1 2364.2325 1.27 72975 22925 4 2364.236078 592.0654 "Malate dehydrogenase, mitochondrial OS=Homo sapiens OX=9606 GN=MDH2 PE=1 SV=3" 5.21 3687.4 - 271438 - - - 1.5024 - 2.132 0.512 - 63.3 1 2 0 0.0036 22 0 0 0 3.63E+06 2.86E+06 - - - 3.9292 1 221125_WJC_METTL3_EV_vs_WT_F05.22933.22933.3 4.39E-08 17/92 K.QTQTFTTYSDNQPGVLIQVYEGER[166.11].A "sp|P11142|HSP7C_HUMAN,tr|E9PNE6|E9PNE6_HUMAN,tr|A8K7Q2|A8K7Q2_HUMAN,tr|E9PKE3|E9PKE3_HUMAN,tr|E9PS65|E9PS65_HUMAN" 5 2783.3278 0.16 72981 22933 3 2783.327374 928.7832 Heat shock cognate 71 kDa protein OS=Homo sapiens OX=9606 GN=HSPA8 PE=1 SV=1 4.14 3688.4 - 545632 - - - -0.1437 - 3.106 0.596 - 269.2 1 2 0 -0.0004 24 0 0 0 1.28E+08 7.93E+08 - - - 7.817 0.9998 221125_WJC_METTL3_EV_vs_WT_F05.22940.22940.4 0.000515 14/144 K.ELTTEIDNNIEQISSYKSEITELRR.N "sp|P13645|K1C10_HUMAN,tr|A0A1B0GVI3|A0A1B0GVI3_HUMAN" 2 2980.4989 999 72986 22940 4 2980.498587 746.132 "Keratin, type I cytoskeletal 10 OS=Homo sapiens OX=9606 GN=KRT10 PE=1 SV=6" 4.42 3689.4 - 398641 - - - -0.1134 - 2.565 0.474 - 103.3 1 2 1 -0.0003 25 0 0 0 5.56E+06 0.00E+00 - - - 3.6513 1 221125_WJC_METTL3_EV_vs_WT_F05.22941.22941.3 3.50E-08 Dec-92 R.EHPFVLQSVGGQTLTVFTESSSDK[136.11].L sp|P13984|T2FB_HUMAN 1 2600.285 1.58 72987 22941 3 2600.288951 867.7689 General transcription factor IIF subunit 2 OS=Homo sapiens OX=9606 GN=GTF2F2 PE=1 SV=2 4.65 3689.5 - 242620 - - - 1.5341 - 2.494 0.584 - 81.9 1 2 0 0.004 24 0 0 0 6.49E+06 4.12E+06 - - - 7.1725 0.846 221125_WJC_METTL3_EV_vs_WT_F05.22946.22946.2 0.00204 30-Nov K.KVSQEILELLNTTTAK[136.11].E "sp|Q86U44|MTA70_HUMAN,tr|H0YFV6|H0YFV6_HUMAN" 2 1795.0182 - 72989 22946 2 1796.01339 898.5164 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 6.14 3690.2 - 200601 - - - 554.4011 - 2 0.418 - 255.9 1 2 0 0.9952 16 0 0 0 - - - - - 3.52 1 221125_WJC_METTL3_EV_vs_WT_F05.22957.22957.2 1.04E-10 22/30 K.K[136.11]VSQEILELLNTTTAK[136.11].E "sp|Q86U44|MTA70_HUMAN,tr|H0YFV6|H0YFV6_HUMAN" 2 1803.0324 0 72994 22957 2 1803.027687 902.5235 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 6.14 3691.6 - 1.12E+07 - - - -2.6306 - 4.01 0.702 - 1403.2 1 2 0 -0.0047 16 0 0 0 1.84E+06 2.47E+09 - - - 7.6389 0.7945 221125_WJC_METTL3_EV_vs_WT_F05.22964.22964.2 0.0916 14-Jul E.LLNTTTAK[136.11].E "sp|Q86U44|MTA70_HUMAN,tr|H0YFV6|H0YFV6_HUMAN" 2 868.5109 0.001 72999 22964 2 868.508824 435.2627 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 8.75 3692.4 - 157401 - - - -2.4283 - 1.408 0.267 - 119.8 1 1 0 -0.0021 8 0 0 0 0.00E+00 1.98E+07 - - - 2.0444 0.8366 221125_WJC_METTL3_EV_vs_WT_F05.22968.22968.3 1.74E-06 Aug-92 R.NGPGFHNDIDSNSTIQEILIPASK.V sp|Q96I24|FUBP3_HUMAN 1 2566.2663 -1 73001 22968 3 2567.249454 856.4294 Far upstream element-binding protein 3 OS=Homo sapiens OX=9606 GN=FUBP3 PE=1 SV=2 4.54 3693 - 813481 - - - 383.0888 - 1.774 0.54 - 37.6 1 2 0 0.9831 24 0 0 0 0.00E+00 0.00E+00 - - - 5.6195 1 221125_WJC_METTL3_EV_vs_WT_F05.22973.22973.3 6.46E-11 21/92 K.QTQTFTTYSDNQPGVLIQVYEGER.A "sp|P11142|HSP7C_HUMAN,tr|E9PNE6|E9PNE6_HUMAN,tr|A8K7Q2|A8K7Q2_HUMAN,tr|E9PKE3|E9PKE3_HUMAN,tr|E9PS65|E9PS65_HUMAN" 5 2773.3195 0.16 73002 22973 3 2773.311109 925.4471 Heat shock cognate 71 kDa protein OS=Homo sapiens OX=9606 GN=HSPA8 PE=1 SV=1 4.14 3693.7 - 1.32E+06 - - - -3.0271 - 3.376 0.648 - 400.2 1 2 0 -0.0084 24 0 0 0 1.28E+08 7.95E+08 - - - 8.5881 0.8973 221125_WJC_METTL3_EV_vs_WT_F05.22984.22984.2 0.0234 18-Oct L.LELLNTTTAK[136.11].E "sp|Q86U44|MTA70_HUMAN,tr|H0YFV6|H0YFV6_HUMAN" 2 1110.6376 0.001 73005 22984 2 1110.634087 556.3261 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 6 3695.4 - 259425 - - - -3.154 - 2.274 0.268 - 318.4 1 1 0 -0.0035 10 0 0 0 0.00E+00 1.51E+07 - - - 3.3125 1 221125_WJC_METTL3_EV_vs_WT_F05.22995.22995.4 9.58E-12 25/234 R.ASPATQPPPLLPPSATGPDATVGGPAPTPLLPPSATASVK.M sp|Q07666|KHDR1_HUMAN 1 3725.988 1.68 73010 22995 4 3725.976123 932.5043 "KH domain-containing, RNA-binding, signal transduction-associated protein 1 OS=Homo sapiens OX=9606 GN=KHDRBS1 PE=1 SV=1" 5.88 3696.7 - 1.37E+06 - - - -3.1857 - 3.663 0.64 - 126.2 1 2 0 -0.0119 40 0 0 0 7.82E+07 4.64E+07 - - - 5.168 0.9975 221125_WJC_METTL3_EV_vs_WT_F05.23025.23025.3 4.71E-10 17/72 R.KPANDITSQLEINFGDLGR.P sp|Q8NC51|PAIRB_HUMAN 1 2087.0647 1.41 73023 23025 3 2087.067705 696.6955 Plasminogen activator inhibitor 1 RNA-binding protein OS=Homo sapiens OX=9606 GN=SERBP1 PE=1 SV=2 4.56 3700.6 - 704054 - - - 1.424 - 3.41 0.513 - 382.8 1 1 0 0.003 19 0 0 0 3.87E+07 2.74E+07 - - - 7.2724 0.979 221125_WJC_METTL3_EV_vs_WT_F05.23027.23027.3 8.77E-09 18/72 R.K[136.11]PANDITSQLEINFGDLGR[166.11].P sp|Q8NC51|PAIRB_HUMAN 1 2105.0872 1.36 73024 23027 3 2105.0766 702.703 Plasminogen activator inhibitor 1 RNA-binding protein OS=Homo sapiens OX=9606 GN=SERBP1 PE=1 SV=2 4.56 3700.8 - 1.10E+06 - - - -5.0368 - 3.468 0.562 - 416.4 1 1 0 -0.0106 19 0 0 0 3.68E+07 2.71E+07 - - - 7.858 1 221125_WJC_METTL3_EV_vs_WT_F05.23029.23029.2 1.51E-10 17/38 K.TIGGGDDSFNTFFSETGAGK[136.11].H "sp|Q6PEY2|TBA3E_HUMAN,sp|P0DPH7|TBA3C_HUMAN,sp|Q71U36|TBA1A_HUMAN,sp|P0DPH8|TBA3D_HUMAN,sp|P68363|TBA1B_HUMAN,sp|Q9BQE3|TBA1C_HUMAN,tr|F8W0F6|F8W0F6_HUMAN,tr|F8VS66|F8VS66_HUMAN,tr|F8VWV9|F8VWV9_HUMAN,tr|F8VRZ4|F8VRZ4_HUMAN,tr|F8VVB9|F8VVB9_HUMAN,tr|A0A1W2PQM2|A0A1W2PQM2_HUMAN,tr|F5H5D3|F5H5D3_HUMAN,tr|F8VRK0|F8VRK0_HUMAN,tr|F8VQQ4|F8VQQ4_HUMAN,tr|F8VX09|F8VX09_HUMAN,tr|A0A7P0Z4A1|A0A7P0Z4A1_HUMAN" 17 2014.9 0.5 73025 23029 2 2014.895838 1008.4573 Tubulin alpha-3E chain OS=Homo sapiens OX=9606 GN=TUBA3E PE=1 SV=2 4.03 3701 - 606366 - - - -2.0482 - 3.202 0.758 - 585.8 1 2 0 -0.0041 20 0 0 0 6.54E+06 1.32E+07 - - - 7.4995 1 221125_WJC_METTL3_EV_vs_WT_F05.23031.23031.4 2.54E-07 16/90 K.K[136.11]VSQEILELLNTTTAK[136.11].E "sp|Q86U44|MTA70_HUMAN,tr|H0YFV6|H0YFV6_HUMAN" 2 1803.0324 0.02 73026 23031 4 1803.028387 451.7654 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 6.14 3701.3 - 175526 - - - -2.2423 - 3.055 0.544 - 214.4 1 2 0 -0.004 16 0 0 0 2.54E+05 1.44E+07 - - - 4.3533 0.9997 221125_WJC_METTL3_EV_vs_WT_F05.23035.23035.4 7.26E-10 19/132 K.TPELNLDQFHDKTPYTIMFGPDK.C "sp|P27824|CALX_HUMAN,tr|A0A7P0T937|A0A7P0T937_HUMAN,tr|A0A7P0T840|A0A7P0T840_HUMAN,tr|D6RFL1|D6RFL1_HUMAN,tr|A0A7P0Z4H2|A0A7P0Z4H2_HUMAN,tr|A0A7P0TB65|A0A7P0TB65_HUMAN,tr|A0A7P0TAE9|A0A7P0TAE9_HUMAN,tr|D6RGY2|D6RGY2_HUMAN,tr|A0A7P0T8G1|A0A7P0T8G1_HUMAN,tr|A0A7P0Z4D6|A0A7P0Z4D6_HUMAN,tr|A0A7P0Z484|A0A7P0Z484_HUMAN,tr|A0A7P0TAR9|A0A7P0TAR9_HUMAN,tr|A0A7P0T9L0|A0A7P0T9L0_HUMAN" 13 2706.3 1.54 73027 23035 4 2706.300867 677.5823 Calnexin OS=Homo sapiens OX=9606 GN=CANX PE=1 SV=2 4.66 3701.8 - 730009 - - - 0.3374 - 3.168 0.425 - 244.2 1 2 1 0.0009 23 0 0 0 1.33E+07 8.61E+06 - - - 3.2985 0.999 221125_WJC_METTL3_EV_vs_WT_F05.23038.23038.4 1.71E-07 13/132 K.TPELNLDQFHDK[136.11]TPYTIMFGPDK[136.11].C "sp|P27824|CALX_HUMAN,tr|A0A7P0T937|A0A7P0T937_HUMAN,tr|A0A7P0T840|A0A7P0T840_HUMAN,tr|D6RFL1|D6RFL1_HUMAN,tr|A0A7P0Z4H2|A0A7P0Z4H2_HUMAN,tr|A0A7P0TB65|A0A7P0TB65_HUMAN,tr|A0A7P0TAE9|A0A7P0TAE9_HUMAN,tr|D6RGY2|D6RGY2_HUMAN,tr|A0A7P0T8G1|A0A7P0T8G1_HUMAN,tr|A0A7P0Z4D6|A0A7P0Z4D6_HUMAN,tr|A0A7P0Z484|A0A7P0Z484_HUMAN,tr|A0A7P0TAR9|A0A7P0TAR9_HUMAN,tr|A0A7P0T9L0|A0A7P0T9L0_HUMAN" 13 2722.3284 1.53 73028 23038 4 2722.31889 681.5894 Calnexin OS=Homo sapiens OX=9606 GN=CANX PE=1 SV=2 4.66 3702.2 - 471192 - - - -3.4764 - 2.496 0.465 - 125.2 1 2 1 -0.0095 23 0 0 0 1.30E+07 8.51E+06 - - - 3.5671 0.9941 221125_WJC_METTL3_EV_vs_WT_F05.23040.23040.4 5.61E-07 23/234 R.ASPATQPPPLLPPSATGPDATVGGPAPTPLLPPSATASVK[136.11].M sp|Q07666|KHDR1_HUMAN 1 3734.0022 1.67 73030 23040 4 3734.992793 934.5078 "KH domain-containing, RNA-binding, signal transduction-associated protein 1 OS=Homo sapiens OX=9606 GN=KHDRBS1 PE=1 SV=1" 5.88 3702.5 - 1.30E+06 - - - 265.2918 - 2.665 0.516 - 82.9 1 2 0 0.9906 40 0 0 0 7.87E+07 4.70E+07 - - - 3.7258 0.9806 221125_WJC_METTL3_EV_vs_WT_F05.23051.23051.3 4.04E-08 15/68 N.TIDDLKDQIVDLTVGNNK.T sp|P35527|K1C9_HUMAN 1 2000.0426 1536.97 73034 23051 3 2000.038118 667.6881 "Keratin, type I cytoskeletal 9 OS=Homo sapiens OX=9606 GN=KRT9 PE=1 SV=3" 4.14 3704 - 531536 - - - -2.241 - 2.534 0.563 - 169.7 1 1 1 -0.0045 18 0 0 0 3.91E+07 2.54E+04 - - - 7.1309 1 221125_WJC_METTL3_EV_vs_WT_F05.23056.23056.3 5.26E-14 16/80 K.TC[160.03]QENSDVFQQEQGISDLLGK.S "sp|Q8IWI9|MGAP_HUMAN,tr|H3BU53|H3BU53_HUMAN" 2 2395.0962 1.87 73036 23056 3 2395.092076 799.3727 MAX gene-associated protein OS=Homo sapiens OX=9606 GN=MGA PE=1 SV=4 3.92 3704.6 - 366148 - - - -1.7089 - 3.709 0.768 - 367.4 1 2 0 -0.0041 21 0 0 0 8.13E+06 4.36E+06 - - - 10.2438 0.9999 221125_WJC_METTL3_EV_vs_WT_F05.23058.23058.3 1.79E-06 16/76 K.HAASDVDLEIESLLNQQSTK[136.11].E "sp|Q86U44|MTA70_HUMAN,tr|F5H6D8|F5H6D8_HUMAN,tr|H0YFV6|H0YFV6_HUMAN,tr|B4DTN4|B4DTN4_HUMAN" 4 2205.1005 0.001 73037 23058 3 2205.090471 736.0408 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 4.31 3704.8 - 197847 - - - -4.5281 - 3.537 0.592 - 287.8 1 2 0 -0.01 20 0 0 0 0.00E+00 2.23E+06 - - - 8.2022 1 221125_WJC_METTL3_EV_vs_WT_F05.23068.23068.3 8.56E-09 14/76 K.NNQFQALLQYADPVSAQHAK[136.11].L "sp|P26599|PTBP1_HUMAN,tr|A0A6Q8PEX4|A0A6Q8PEX4_HUMAN,tr|A0A0U1RRM4|A0A0U1RRM4_HUMAN,tr|A6NLN1|A6NLN1_HUMAN,tr|K7EKJ7|K7EKJ7_HUMAN,tr|A0A087WU68|A0A087WU68_HUMAN,tr|A0A7I2V4H6|A0A7I2V4H6_HUMAN,tr|A0A7I2V621|A0A7I2V621_HUMAN,tr|K7EK45|K7EK45_HUMAN" 9 2250.1273 1.43 73043 23068 3 2250.121683 751.0497 Polypyrimidine tract-binding protein 1 OS=Homo sapiens OX=9606 GN=PTBP1 PE=1 SV=1 6.74 3706.2 - 335223 - - - -2.4874 - 3.201 0.564 - 161.8 1 2 0 -0.0056 20 0 0 0 1.71E+08 1.20E+08 - - - 7.6491 1 221125_WJC_METTL3_EV_vs_WT_F05.23070.23070.3 1.64E-06 14/76 K.NNQFQALLQYADPVSAQHAK.L "sp|P26599|PTBP1_HUMAN,tr|A0A6Q8PEX4|A0A6Q8PEX4_HUMAN,tr|A0A0U1RRM4|A0A0U1RRM4_HUMAN,tr|A6NLN1|A6NLN1_HUMAN,tr|K7EKJ7|K7EKJ7_HUMAN,tr|A0A087WU68|A0A087WU68_HUMAN,tr|A0A7I2V4H6|A0A7I2V4H6_HUMAN,tr|A0A7I2V621|A0A7I2V621_HUMAN,tr|K7EK45|K7EK45_HUMAN" 9 2242.1131 1.14 73044 23070 3 2242.111281 748.3783 Polypyrimidine tract-binding protein 1 OS=Homo sapiens OX=9606 GN=PTBP1 PE=1 SV=1 6.74 3706.4 - 354635 - - - -0.8024 - 3.035 0.498 - 203.1 1 2 0 -0.0018 20 0 0 0 1.36E+08 1.20E+08 - - - 6.7851 1 221125_WJC_METTL3_EV_vs_WT_F05.23071.23071.3 9.65E-08 12/156 R.ASPATQPPPLLPPSATGPDATVGGPAPTPLLPPSATASVK[136.11].M sp|Q07666|KHDR1_HUMAN 1 3734.0022 1.41 73045 23071 3 3734.001343 1245.6747 "KH domain-containing, RNA-binding, signal transduction-associated protein 1 OS=Homo sapiens OX=9606 GN=KHDRBS1 PE=1 SV=1" 5.88 3706.5 - 228980 - - - -0.2276 - 2.011 0.581 - 37.8 1 2 0 -0.0008 40 0 0 0 2.59E+07 1.84E+07 - - - 6.6246 1 221125_WJC_METTL3_EV_vs_WT_F05.23072.23072.3 1.26E-09 14/156 R.ASPATQPPPLLPPSATGPDATVGGPAPTPLLPPSATASVK.M sp|Q07666|KHDR1_HUMAN 1 3725.988 1.41 73046 23072 3 3725.987355 1243.0033 "KH domain-containing, RNA-binding, signal transduction-associated protein 1 OS=Homo sapiens OX=9606 GN=KHDRBS1 PE=1 SV=1" 5.88 3706.6 - 433590 - - - -0.1712 - 2.489 0.579 - 54.9 1 2 0 -0.0006 40 0 0 0 2.52E+07 1.78E+07 - - - 7.093 0.9999 221125_WJC_METTL3_EV_vs_WT_F05.23076.23076.4 2.78E-08 18/156 K.DLPRPSEVNETILRPLNVEPPLTDLQK.S sp|Q99459|CDC5L_HUMAN 1 3082.6663 2.15 73048 23076 4 3082.661741 771.6738 Cell division cycle 5-like protein OS=Homo sapiens OX=9606 GN=CDC5L PE=1 SV=2 4.51 3707.2 - 411732 - - - -1.4676 - 3.039 0.467 - 171.4 1 2 0 -0.0045 27 0 0 0 3.30E+07 1.53E+07 - - - 3.6373 0.8626 221125_WJC_METTL3_EV_vs_WT_F05.23078.23078.2 0.0105 May-36 R.DSQGNQEPTTTPDAMVQPF.T "sp|O43251|RFOX2_HUMAN,tr|A0A0G2JRA5|A0A0G2JRA5_HUMAN,tr|B0QYY7|B0QYY7_HUMAN,tr|A0A0G2JSB3|A0A0G2JSB3_HUMAN" 4 2061.8949 - 73050 23078 2 2061.891764 1031.9548 RNA binding protein fox-1 homolog 2 OS=Homo sapiens OX=9606 GN=RBFOX2 PE=1 SV=3 3.49 3707.4 - 148554 - - - -1.5452 - 1.131 0.352 - 35.5 1 1 0 -0.0032 19 0 0 0 - - - - - 1.9425 1 221125_WJC_METTL3_EV_vs_WT_F05.23081.23081.3 2.69E-11 18/60 K.K[136.11]VSQEILELLNTTTAK[136.11].E "sp|Q86U44|MTA70_HUMAN,tr|H0YFV6|H0YFV6_HUMAN" 2 1803.0324 0.01 73052 23081 3 1803.029992 602.0181 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 6.14 3707.8 - 4.46E+07 - - - -1.3522 - 3.814 0.69 - 560.1 1 2 0 -0.0024 16 0 0 0 1.51E+08 1.67E+10 - - - 9.667 0.9371 221125_WJC_METTL3_EV_vs_WT_F05.23083.23083.3 0.00264 Jul-72 R.DSQGNQEPTTTPDAMVQPF.T "sp|O43251|RFOX2_HUMAN,tr|A0A0G2JRA5|A0A0G2JRA5_HUMAN,tr|B0QYY7|B0QYY7_HUMAN,tr|A0A0G2JSB3|A0A0G2JSB3_HUMAN" 4 2061.8949 - 73053 23083 3 2061.89488 688.3056 RNA binding protein fox-1 homolog 2 OS=Homo sapiens OX=9606 GN=RBFOX2 PE=1 SV=3 3.49 3708 - 251381 - - - -0.0339 - 1.376 0.387 - 28.5 1 1 0 -0.0001 19 0 0 0 - - - - - 3.6388 0.9999 221125_WJC_METTL3_EV_vs_WT_F05.23084.23084.4 1.22E-06 14/156 K.DLPR[166.11]PSEVNETILR[166.11]PLNVEPPLTDLQK[136.11].S sp|Q99459|CDC5L_HUMAN 1 3110.697 1.65 73054 23084 4 3110.701918 778.6815 Cell division cycle 5-like protein OS=Homo sapiens OX=9606 GN=CDC5L PE=1 SV=2 4.51 3708.1 - 310122 - - - 1.5794 - 2.534 0.418 - 78.2 1 2 0 0.0049 27 0 0 0 9.29E+06 5.62E+06 - - - 3.1538 1 221125_WJC_METTL3_EV_vs_WT_F05.23085.23085.3 4.08E-09 14/72 K.TIHLLTSLDEGIEQVQQSR.G "sp|Q8WV92|MITD1_HUMAN,tr|H7C3Q6|H7C3Q6_HUMAN" 2 2166.1281 1.41 73055 23085 3 2166.131026 723.05 MIT domain-containing protein 1 OS=Homo sapiens OX=9606 GN=MITD1 PE=1 SV=1 4.65 3708.3 - 211376 - - - 1.3688 - 2.863 0.586 - 276.8 1 2 0 0.003 19 0 0 0 1.10E+07 7.77E+06 - - - 7.6567 0.9965 221125_WJC_METTL3_EV_vs_WT_F05.23086.23086.4 0.00757 Oct-96 K.SK[136.11]GLAPDLPEDLYHLIK[136.11].K "sp|P62277|RS13_HUMAN,tr|J3KMX5|J3KMX5_HUMAN" 2 1924.0641 1.06 73056 23086 4 1924.059845 482.0233 40S ribosomal protein S13 OS=Homo sapiens OX=9606 GN=RPS13 PE=1 SV=2 5.36 3708.4 - 171210 - - - -2.1928 - 1.864 0.333 - 84.3 1 2 1 -0.0042 17 0 0 0 4.25E+06 4.01E+06 - - - 2.3395 0.9944 221125_WJC_METTL3_EV_vs_WT_F05.23089.23089.3 0.102 May-88 R.DNLTLWTSDSAGEEC[160.03]DAAEGAEN.- sp|P27348|1433T_HUMAN 1 2453.9765 - 73057 23089 3 2453.985233 818.9994 14-3-3 protein theta OS=Homo sapiens OX=9606 GN=YWHAQ PE=1 SV=1 3.26 3708.8 - 182142 - - - 3.5559 - 0.936 0.444 - 20 1 2 0 0.0087 23 0 0 0 - - - - - 3.3326 0.822 221125_WJC_METTL3_EV_vs_WT_F05.23096.23096.4 0.427 6/102 R.EKEFGDKVNLLSVLEAAK.M sp|Q9BRX8|PXL2A_HUMAN 1 1989.0783 1.75 73061 23096 4 1989.07989 498.2768 Peroxiredoxin-like 2A OS=Homo sapiens OX=9606 GN=PRXL2A PE=1 SV=3 4.87 3709.7 - 136937 - - - 0.821 - 1.354 0.147 - 31.6 1 2 2 0.0016 18 0 0 0 2.65E+06 1.51E+06 - - - 0.6089 1 221125_WJC_METTL3_EV_vs_WT_F05.23098.23098.3 1.21E-09 17/72 K.TIHLLTSLDEGIEQVQQSR[166.11].G "sp|Q8WV92|MITD1_HUMAN,tr|H7C3Q6|H7C3Q6_HUMAN" 2 2176.1363 1.43 73062 23098 3 2176.138681 726.3861 MIT domain-containing protein 1 OS=Homo sapiens OX=9606 GN=MITD1 PE=1 SV=1 4.65 3709.9 - 337515 - - - 1.0799 - 3.454 0.556 - 405.8 1 2 0 0.0023 19 0 0 0 1.11E+07 7.77E+06 - - - 7.7835 0.906 221125_WJC_METTL3_EV_vs_WT_F05.23099.23099.4 0.383 7/102 R.AREEENYSFLPLVHNIIK.C "sp|Q9NWA0|MED9_HUMAN,tr|J3KTK5|J3KTK5_HUMAN" 2 2171.1375 1.81 73063 23099 4 2171.143639 543.7917 Mediator of RNA polymerase II transcription subunit 9 OS=Homo sapiens OX=9606 GN=MED9 PE=1 SV=1 5.5 3710.1 - 104527 - - - 2.8257 - 1.355 0.214 - 42.1 1 2 1 0.0061 18 0 0 0 3.19E+06 1.77E+06 - - - 1.191 1 221125_WJC_METTL3_EV_vs_WT_F05.23100.23100.3 4.34E-05 19/68 R.C[160.03]QHAAHIISELILTAQER.D sp|Q96I24|FUBP3_HUMAN 1 2089.0739 6.2 73064 23100 3 2089.077187 697.3652 Far upstream element-binding protein 3 OS=Homo sapiens OX=9606 GN=FUBP3 PE=1 SV=2 6 3710.2 - 165215 - - - 1.5935 - 3.612 0.576 - 612.9 1 2 0 0.0033 18 0 0 0 2.29E+07 3.70E+06 - - - 8.1589 0.9992 221125_WJC_METTL3_EV_vs_WT_F05.23103.23103.3 2.17E-05 Oct-68 R.EKEFGDKVNLLSVLEAAK.M sp|Q9BRX8|PXL2A_HUMAN 1 1989.0783 2.04 73067 23103 3 1989.084061 664.0334 Peroxiredoxin-like 2A OS=Homo sapiens OX=9606 GN=PRXL2A PE=1 SV=3 4.87 3710.6 - 72895.8 - - - 2.9179 - 2.015 0.513 - 75.3 1 2 2 0.0058 18 0 0 0 1.52E+06 7.46E+05 - - - 6.0024 1 221125_WJC_METTL3_EV_vs_WT_F05.23107.23107.3 2.11E-08 9/116 R.NSSAQAFLGPENPEEPYLDGINYNC[160.03]VAPGK.R "sp|Q14683|SMC1A_HUMAN,tr|G8JLG1|G8JLG1_HUMAN,tr|A0A6Q8PHC3|A0A6Q8PHC3_HUMAN,tr|V9GY57|V9GY57_HUMAN" 4 3250.4877 1.64 73069 23107 3 3250.490649 1084.5032 Structural maintenance of chromosomes protein 1A OS=Homo sapiens OX=9606 GN=SMC1A PE=1 SV=2 4 3711.2 - 168705 - - - 0.9048 - 2.118 0.638 - 36 1 2 0 0.0029 30 0 0 0 3.24E+06 1.97E+06 - - - 7.3788 0.9998 221125_WJC_METTL3_EV_vs_WT_F05.23108.23108.4 0.000108 Oct-96 K.SKGLAPDLPEDLYHLIK.K "sp|P62277|RS13_HUMAN,tr|J3KMX5|J3KMX5_HUMAN" 2 1908.0357 1.06 73070 23108 4 1908.034916 478.0162 40S ribosomal protein S13 OS=Homo sapiens OX=9606 GN=RPS13 PE=1 SV=2 5.36 3711.3 - 246827 - - - -0.392 - 2.217 0.469 - 71.5 1 2 1 -0.0007 17 0 0 0 4.25E+06 4.01E+06 - - - 3.5844 0.9999 221125_WJC_METTL3_EV_vs_WT_F05.23109.23109.3 4.81E-08 Dec-64 K.SKGLAPDLPEDLYHLIK.K "sp|P62277|RS13_HUMAN,tr|J3KMX5|J3KMX5_HUMAN" 2 1908.0357 1.73 73071 23109 3 1908.035578 637.0192 40S ribosomal protein S13 OS=Homo sapiens OX=9606 GN=RPS13 PE=1 SV=2 5.36 3711.4 - 188234 - - - -0.0451 - 2.73 0.536 - 199.8 1 2 1 -0.0001 17 0 0 0 3.55E+06 2.04E+06 - - - 7.053 0.8212 221125_WJC_METTL3_EV_vs_WT_F05.23116.23116.4 2.32 5/102 K.GTSIVVPEPLHFLLPGKK.N "sp|Q9NUQ7|UFSP2_HUMAN,tr|D6RGX2|D6RGX2_HUMAN,tr|H0YA18|H0YA18_HUMAN" 3 1931.1244 1.03 73076 23116 4 1931.124648 483.7884 Ufm1-specific protease 2 OS=Homo sapiens OX=9606 GN=UFSP2 PE=1 SV=3 8.6 3712.4 - 130571 - - - 0.1181 - 1.076 0.107 - 15.1 1 2 0 0.0002 18 0 0 0 2.96E+06 2.87E+06 - - - 0.1824 0.9976 221125_WJC_METTL3_EV_vs_WT_F05.23119.23119.2 0.000116 Jul-44 R.DNLTLWTSDSAGEEC[160.03]DAAEGAEN.- sp|P27348|1433T_HUMAN 1 2453.9765 - 73079 23119 2 2453.988437 1227.9955 14-3-3 protein theta OS=Homo sapiens OX=9606 GN=YWHAQ PE=1 SV=1 3.26 3712.8 - 113377 - - - 4.8615 - 1.495 0.627 - 75.2 1 2 0 0.0119 23 0 0 0 - - - - - 4.6569 0.9997 221125_WJC_METTL3_EV_vs_WT_F05.23124.23124.3 6.71E-06 Nov-96 K.ETVSQRPGATVPTDFATFPSSAFLR.A "sp|Q14203|DCTN1_HUMAN,tr|A0A804CDA6|A0A804CDA6_HUMAN,tr|E7EX90|E7EX90_HUMAN,tr|A0A7P0Z4C3|A0A7P0Z4C3_HUMAN,tr|E7EWF7|E7EWF7_HUMAN" 5 2681.3449 3.47 73082 23124 3 2681.355621 894.7889 Dynactin subunit 1 OS=Homo sapiens OX=9606 GN=DCTN1 PE=1 SV=3 6.17 3713.4 - 203628 - - - 3.9872 - 2.267 0.538 - 60.4 1 2 0 0.0107 25 0 0 0 1.58E+07 4.54E+06 - - - 6.4182 1 221125_WJC_METTL3_EV_vs_WT_F05.23128.23128.3 1.90E-05 10/104 K.NAISLPVIGGPQALTLPTAQAPPK[136.11]PPR[166.11].L sp|O14613|BORG1_HUMAN 1 2721.566 2.83 73084 23128 3 2721.565387 908.196 Cdc42 effector protein 2 OS=Homo sapiens OX=9606 GN=CDC42EP2 PE=1 SV=1 11 3714 - 173191 - - - -0.2403 - 2.164 0.615 - 63.7 1 2 0 -0.0007 27 0 0 0 2.10E+07 7.42E+06 - - - 7.1725 0.9999 221125_WJC_METTL3_EV_vs_WT_F05.23129.23129.3 1.68E-10 Dec-88 K.SENLGQGDK[136.11]PDYFSSVATVVYLR[166.11].K sp|P27694|RFA1_HUMAN 1 2562.2721 0.27 73085 23129 3 2562.283155 855.098 Replication protein A 70 kDa DNA-binding subunit OS=Homo sapiens OX=9606 GN=RPA1 PE=1 SV=2 4.56 3714.1 - 115405 - - - 4.3134 - 2.673 0.631 - 138.4 1 2 0 0.0111 23 0 0 0 4.16E+05 1.55E+06 - - - 7.8785 1 221125_WJC_METTL3_EV_vs_WT_F05.23131.23131.3 1.36E-11 14/96 K.HNVEVLGILSDDVETDTVAPGENLK.L "sp|P15170|ERF3A_HUMAN,tr|H3BR35|H3BR35_HUMAN" 2 2663.329 0.43 73087 23131 3 2663.340004 888.7836 Eukaryotic peptide chain release factor GTP-binding subunit ERF3A OS=Homo sapiens OX=9606 GN=GSPT1 PE=1 SV=1 4.01 3714.4 - 181079 - - - 4.1294 - 3.105 0.715 - 144.3 1 2 0 0.011 25 0 0 0 1.49E+06 3.43E+06 - - - 9.1151 0.9856 221125_WJC_METTL3_EV_vs_WT_F05.23132.23132.4 0.0719 6/102 K.GTSIVVPEPLHFLLPGK[136.11]K[136.11].N "sp|Q9NUQ7|UFSP2_HUMAN,tr|D6RGX2|D6RGX2_HUMAN,tr|H0YA18|H0YA18_HUMAN" 3 1947.1528 1.03 73088 23132 4 1947.159948 487.7955 Ufm1-specific protease 2 OS=Homo sapiens OX=9606 GN=UFSP2 PE=1 SV=3 8.6 3714.5 - 146023 - - - 3.6607 - 1.285 0.266 - 25.3 1 2 0 0.0071 18 0 0 0 2.96E+06 2.87E+06 - - - 1.6252 0.9999 221125_WJC_METTL3_EV_vs_WT_F05.23139.23139.4 2.49E-10 15/132 R.VANILHDDC[160.03]AFLSAFGDVSKPER.Y sp|Q9BS26|ERP44_HUMAN 1 2560.238 0.98 73093 23139 4 2560.248032 641.0668 Endoplasmic reticulum resident protein 44 OS=Homo sapiens OX=9606 GN=ERP44 PE=1 SV=1 4.66 3715.5 - 130200 - - - 3.9094 - 2.919 0.599 - 171.4 1 2 0 0.01 23 0 0 0 1.83E+06 1.87E+06 - - - 4.784 0.9999 221125_WJC_METTL3_EV_vs_WT_F05.23147.23147.3 0.000221 Sep-96 K.HNVEVLGILSDDVETDTVAPGENLK[136.11].L "sp|P15170|ERF3A_HUMAN,tr|H3BR35|H3BR35_HUMAN" 2 2671.3432 0.43 73097 23147 3 2671.348576 891.455 Eukaryotic peptide chain release factor GTP-binding subunit ERF3A OS=Homo sapiens OX=9606 GN=GSPT1 PE=1 SV=1 4.01 3716.6 - 198799 - - - 2.0102 - 1.883 0.492 - 62.7 1 2 0 0.0054 25 0 0 0 1.49E+06 3.43E+06 - - - 5.4798 0.9999 221125_WJC_METTL3_EV_vs_WT_F05.23148.23148.3 1.46E-09 17/72 K.IRELESQISELQEDLESER.A sp|P35579|MYH9_HUMAN 1 2302.1288 1.31 73098 23148 3 2302.134235 768.3836 Myosin-9 OS=Homo sapiens OX=9606 GN=MYH9 PE=1 SV=4 4.06 3716.8 - 223451 - - - 2.3396 - 3.321 0.604 - 357.7 1 2 1 0.0054 19 0 0 0 1.64E+07 1.25E+07 - - - 8.2213 0.9964 221125_WJC_METTL3_EV_vs_WT_F05.23150.23150.4 0.0194 7/114 K.NNQFQALLQYADPVSAQHAK.L "sp|P26599|PTBP1_HUMAN,tr|A0A6Q8PEX4|A0A6Q8PEX4_HUMAN,tr|A0A0U1RRM4|A0A0U1RRM4_HUMAN,tr|A6NLN1|A6NLN1_HUMAN,tr|K7EKJ7|K7EKJ7_HUMAN,tr|A0A087WU68|A0A087WU68_HUMAN,tr|A0A7I2V4H6|A0A7I2V4H6_HUMAN,tr|A0A7I2V621|A0A7I2V621_HUMAN,tr|K7EK45|K7EK45_HUMAN" 9 2242.1131 1.05 73100 23150 4 2242.122318 561.5355 Polypyrimidine tract-binding protein 1 OS=Homo sapiens OX=9606 GN=PTBP1 PE=1 SV=1 6.74 3717 - 127043 - - - 4.1202 - 1.438 0.346 - 23.3 1 2 0 0.0092 20 0 0 0 1.67E+06 1.59E+06 - - - 2.3565 0.9986 221125_WJC_METTL3_EV_vs_WT_F05.23157.23157.3 0.00573 Aug-48 R.KGHILELLTEVTR.R sp|P31944|CASPE_HUMAN 1 1507.8722 400.81 73105 23157 3 1507.879081 503.6314 Caspase-14 OS=Homo sapiens OX=9606 GN=CASP14 PE=1 SV=2 6.76 3718 - 88847.1 - - - 4.5448 - 1.897 0.43 - 67.6 1 2 0 0.0069 13 0 0 0 4.21E+06 1.05E+04 - - - 5.0681 0.9994 221125_WJC_METTL3_EV_vs_WT_F05.23159.23159.3 0.000114 Dec-68 K.RIQEIIEQLDVTTSEYEK.E "sp|P10809|CH60_HUMAN,tr|A0A7I2V2X6|A0A7I2V2X6_HUMAN,tr|A0A7I2YQK6|A0A7I2YQK6_HUMAN,tr|A0A7I2V599|A0A7I2V599_HUMAN" 4 2193.1165 2.9 73107 23159 3 2193.127736 732.0461 "60 kDa heat shock protein, mitochondrial OS=Homo sapiens OX=9606 GN=HSPD1 PE=1 SV=2" 4.25 3718.2 - 208239 - - - 5.126 - 2.852 0.478 - 183.3 1 2 0 0.0112 18 0 0 0 8.40E+06 2.90E+06 - - - 6.4758 1 221125_WJC_METTL3_EV_vs_WT_F05.23165.23165.3 3.58E-13 26/72 K.IR[166.11]ELESQISELQEDLESER[166.11].A sp|P35579|MYH9_HUMAN 1 2322.1454 1.31 73111 23165 3 2322.161727 775.0557 Myosin-9 OS=Homo sapiens OX=9606 GN=MYH9 PE=1 SV=4 4.06 3719 - 869383 - - - 7.0357 - 4.422 0.688 - 1164.4 1 2 1 0.0163 19 0 0 0 1.64E+07 1.25E+07 - - - 9.8583 0.9992 221125_WJC_METTL3_EV_vs_WT_F05.23183.23183.4 7.89E-05 9/126 R.TDAISEEK[136.11]LR[166.11]EIFGLYGQTTGK[136.11].G "sp|Q9NR31|SAR1A_HUMAN,tr|H0Y5E8|H0Y5E8_HUMAN" 2 2481.2961 0.63 73125 23183 4 2481.297894 621.3313 GTP-binding protein SAR1a OS=Homo sapiens OX=9606 GN=SAR1A PE=1 SV=1 4.87 3721.5 - 227636 - - - 0.7073 - 2.034 0.386 - 52.2 1 2 2 0.0018 22 0 0 0 1.19E+06 1.90E+06 - - - 2.8176 1 221125_WJC_METTL3_EV_vs_WT_F05.23191.23191.3 3.50E-11 20/120 R.GAGNTSSLNPLAVGFVQTPPVISSAHIQDER.V sp|Q9P2D1|CHD7_HUMAN 1 3161.6105 1.32 73131 23191 3 3161.61263 1054.8775 Chromodomain-helicase-DNA-binding protein 7 OS=Homo sapiens OX=9606 GN=CHD7 PE=1 SV=3 5.32 3722.5 - 411153 - - - 0.6607 - 3.199 0.683 - 251.5 1 2 0 0.0021 31 0 0 0 4.09E+06 3.10E+06 - - - 8.8295 0.9993 221125_WJC_METTL3_EV_vs_WT_F05.23192.23192.3 0.0001 Sep-80 K.QC[160.03]ANLQAAIADAEQRGEMALK.D "sp|P04259|K2C6B_HUMAN,sp|P02538|K2C6A_HUMAN" 2 2287.1049 2.12 73132 23192 3 2287.100103 763.3756 "Keratin, type II cytoskeletal 6B OS=Homo sapiens OX=9606 GN=KRT6B PE=1 SV=5" 4.68 3722.7 - 393742 - - - -2.0974 - 2.138 0.45 - 78.7 1 2 1 -0.0048 21 0 0 0 4.85E+06 2.28E+06 - - - 5.3775 0.995 221125_WJC_METTL3_EV_vs_WT_F05.23197.23197.4 3.28E-10 21/114 K.HAASDVDLEIESLLNQQSTK[136.11].E "sp|Q86U44|MTA70_HUMAN,tr|F5H6D8|F5H6D8_HUMAN,tr|H0YFV6|H0YFV6_HUMAN,tr|B4DTN4|B4DTN4_HUMAN" 4 2205.1005 0 73135 23197 4 2206.093191 552.2824 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 4.31 3723.3 - 2.39E+06 - - - 450.1994 - 3.693 0.635 - 352.7 1 2 0 0.9927 20 0 0 0 1.13E+06 3.52E+08 - - - 4.9148 1 221125_WJC_METTL3_EV_vs_WT_F05.23209.23209.3 4.69E-10 36/100 R.QLLAQQLGAESADSIGAVLNSK[136.11]DEQR[166.11].E "sp|Q9HCE5|MET14_HUMAN,tr|A0A0D9SFW0|A0A0D9SFW0_HUMAN,tr|A0A0D9SF88|A0A0D9SF88_HUMAN" 3 2758.4216 0.001 73142 23209 3 2758.415044 920.4812 N6-adenosine-methyltransferase non-catalytic subunit OS=Homo sapiens OX=9606 GN=METTL14 PE=1 SV=2 4.32 3724.9 - 3.54E+06 - - - -2.3843 - 6.104 0.71 - 1677.6 1 2 1 -0.0066 26 0 0 0 0.00E+00 1.37E+08 - - - 10.6157 1 221125_WJC_METTL3_EV_vs_WT_F05.23239.23239.2 7.61E-08 25/38 K.HAASDVDLEIESLLNQQSTK.E "sp|Q86U44|MTA70_HUMAN,tr|F5H6D8|F5H6D8_HUMAN,tr|H0YFV6|H0YFV6_HUMAN,tr|B4DTN4|B4DTN4_HUMAN" 4 2197.0863 0.02 73150 23239 2 2198.07806 1099.5504 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 4.31 3729.2 - 5.95E+06 - - - 451.4179 - 4.55 0.71 - 1416.9 1 2 0 0.9918 20 0 0 0 8.19E+07 4.58E+09 - - - 7.6986 1 221125_WJC_METTL3_EV_vs_WT_F05.23253.23253.3 4.63E-07 22/88 K.SVNDQPSGNLPFLKPDDIQYFDK.L sp|O75533|SF3B1_HUMAN 1 2636.2758 1.27 73153 23253 3 2636.261805 879.7659 Splicing factor 3B subunit 1 OS=Homo sapiens OX=9606 GN=SF3B1 PE=1 SV=3 4.14 3731.3 - 1.56E+06 - - - -5.3268 - 3.884 0.637 - 458.4 1 2 0 -0.014 23 0 0 0 9.35E+07 7.39E+07 - - - 8.8212 0.9999 221125_WJC_METTL3_EV_vs_WT_F05.23255.23255.4 1.27E-06 25/96 K.HVINFDLPSDIEEYVHR.L "sp|O00571|DDX3X_HUMAN,sp|O15523|DDX3Y_HUMAN,tr|A0A2R8YFR4|A0A2R8YFR4_HUMAN,tr|A0A2R8YCW1|A0A2R8YCW1_HUMAN,tr|A0A2R8YDT5|A0A2R8YDT5_HUMAN,tr|A0A2R8Y645|A0A2R8Y645_HUMAN,tr|A0A2R8YF78|A0A2R8YF78_HUMAN,tr|A0A0D9SFB3|A0A0D9SFB3_HUMAN,tr|A0A2R8YFS5|A0A2R8YFS5_HUMAN,tr|A0A0D9SF53|A0A0D9SF53_HUMAN,tr|A0A087WVZ1|A0A087WVZ1_HUMAN,tr|A0A0J9YVQ7|A0A0J9YVQ7_HUMAN,tr|A0A2R8Y5G6|A0A2R8Y5G6_HUMAN,tr|A0A2R8Y7T2|A0A2R8Y7T2_HUMAN,tr|A0A0D9SG12|A0A0D9SG12_HUMAN,tr|F6S8Q4|F6S8Q4_HUMAN,tr|A0A2U3TZJ9|A0A2U3TZJ9_HUMAN,tr|A0A2R8Y4A4|A0A2R8Y4A4_HUMAN" 18 2082.0171 1.47 73155 23255 4 2082.011122 521.5115 ATP-dependent RNA helicase DDX3X OS=Homo sapiens OX=9606 GN=DDX3X PE=1 SV=3 4.72 3731.6 - 1.55E+06 - - - -2.8492 - 3.66 0.54 - 695.4 1 2 0 -0.0059 17 0 0 0 5.82E+07 3.96E+07 - - - 4.375 1 221125_WJC_METTL3_EV_vs_WT_F05.23259.23259.3 0.0476 20/64 K.HVINFDLPSDIEEYVHR.L "sp|O00571|DDX3X_HUMAN,sp|O15523|DDX3Y_HUMAN,tr|A0A2R8YFR4|A0A2R8YFR4_HUMAN,tr|A0A2R8YCW1|A0A2R8YCW1_HUMAN,tr|A0A2R8YDT5|A0A2R8YDT5_HUMAN,tr|A0A2R8Y645|A0A2R8Y645_HUMAN,tr|A0A2R8YF78|A0A2R8YF78_HUMAN,tr|A0A0D9SFB3|A0A0D9SFB3_HUMAN,tr|A0A2R8YFS5|A0A2R8YFS5_HUMAN,tr|A0A0D9SF53|A0A0D9SF53_HUMAN,tr|A0A087WVZ1|A0A087WVZ1_HUMAN,tr|A0A0J9YVQ7|A0A0J9YVQ7_HUMAN,tr|A0A2R8Y5G6|A0A2R8Y5G6_HUMAN,tr|A0A2R8Y7T2|A0A2R8Y7T2_HUMAN,tr|A0A0D9SG12|A0A0D9SG12_HUMAN,tr|F6S8Q4|F6S8Q4_HUMAN,tr|A0A2U3TZJ9|A0A2U3TZJ9_HUMAN,tr|A0A2R8Y4A4|A0A2R8Y4A4_HUMAN" 18 2082.0171 1.59 73156 23259 3 2082.013629 695.013 ATP-dependent RNA helicase DDX3X OS=Homo sapiens OX=9606 GN=DDX3X PE=1 SV=3 4.72 3732.1 - 1.85E+06 - - - -1.645 - 3.902 0.591 - 677.3 1 2 0 -0.0034 17 0 0 0 9.38E+07 5.90E+07 - - - 8.5677 1 221125_WJC_METTL3_EV_vs_WT_F05.23261.23261.3 1.70E-11 23/64 K.HVINFDLPSDIEEYVHR[166.11].L "sp|O00571|DDX3X_HUMAN,sp|O15523|DDX3Y_HUMAN,tr|A0A2R8YFR4|A0A2R8YFR4_HUMAN,tr|A0A2R8YCW1|A0A2R8YCW1_HUMAN,tr|A0A2R8YDT5|A0A2R8YDT5_HUMAN,tr|A0A2R8Y645|A0A2R8Y645_HUMAN,tr|A0A2R8YF78|A0A2R8YF78_HUMAN,tr|A0A0D9SFB3|A0A0D9SFB3_HUMAN,tr|A0A2R8YFS5|A0A2R8YFS5_HUMAN,tr|A0A0D9SF53|A0A0D9SF53_HUMAN,tr|A0A087WVZ1|A0A087WVZ1_HUMAN,tr|A0A0J9YVQ7|A0A0J9YVQ7_HUMAN,tr|A0A2R8Y5G6|A0A2R8Y5G6_HUMAN,tr|A0A2R8Y7T2|A0A2R8Y7T2_HUMAN,tr|A0A0D9SG12|A0A0D9SG12_HUMAN,tr|F6S8Q4|F6S8Q4_HUMAN,tr|A0A2U3TZJ9|A0A2U3TZJ9_HUMAN,tr|A0A2R8Y4A4|A0A2R8Y4A4_HUMAN" 18 2092.0253 1.59 73158 23261 3 2092.021872 698.3491 ATP-dependent RNA helicase DDX3X OS=Homo sapiens OX=9606 GN=DDX3X PE=1 SV=3 4.72 3732.4 - 1.74E+06 - - - -1.6501 - 4.268 0.64 - 1035.9 1 2 0 -0.0035 17 0 0 0 9.34E+07 5.87E+07 - - - 9.3404 1 221125_WJC_METTL3_EV_vs_WT_F05.23264.23264.3 4.94E-13 25/88 R.RDNYVPEVSALDQEIIEVDPDTK.E "sp|P08708|RS17_HUMAN,tr|H3BNC9|H3BNC9_HUMAN,tr|H0YN88|H0YN88_HUMAN,tr|A0A075B716|A0A075B716_HUMAN" 4 2644.2868 1.52 73159 23264 3 2644.280837 882.4362 40S ribosomal protein S17 OS=Homo sapiens OX=9606 GN=RPS17 PE=1 SV=2 3.9 3732.8 - 2.53E+06 - - - -2.2573 - 4.318 0.712 - 535.2 1 2 0 -0.006 23 0 0 0 3.07E+08 2.02E+08 - - - 9.9081 1 221125_WJC_METTL3_EV_vs_WT_F05.23266.23266.4 1.80E-08 22/96 K.HVINFDLPSDIEEYVHR[166.11].L "sp|O00571|DDX3X_HUMAN,sp|O15523|DDX3Y_HUMAN,tr|A0A2R8YFR4|A0A2R8YFR4_HUMAN,tr|A0A2R8YCW1|A0A2R8YCW1_HUMAN,tr|A0A2R8YDT5|A0A2R8YDT5_HUMAN,tr|A0A2R8Y645|A0A2R8Y645_HUMAN,tr|A0A2R8YF78|A0A2R8YF78_HUMAN,tr|A0A0D9SFB3|A0A0D9SFB3_HUMAN,tr|A0A2R8YFS5|A0A2R8YFS5_HUMAN,tr|A0A0D9SF53|A0A0D9SF53_HUMAN,tr|A0A087WVZ1|A0A087WVZ1_HUMAN,tr|A0A0J9YVQ7|A0A0J9YVQ7_HUMAN,tr|A0A2R8Y5G6|A0A2R8Y5G6_HUMAN,tr|A0A2R8Y7T2|A0A2R8Y7T2_HUMAN,tr|A0A0D9SG12|A0A0D9SG12_HUMAN,tr|F6S8Q4|F6S8Q4_HUMAN,tr|A0A2U3TZJ9|A0A2U3TZJ9_HUMAN,tr|A0A2R8Y4A4|A0A2R8Y4A4_HUMAN" 18 2092.0253 1.47 73161 23266 4 2092.019545 524.0136 ATP-dependent RNA helicase DDX3X OS=Homo sapiens OX=9606 GN=DDX3X PE=1 SV=3 4.72 3733.1 - 1.71E+06 - - - -2.7624 - 3.843 0.601 - 565.3 1 2 0 -0.0058 17 0 0 0 5.83E+07 3.97E+07 - - - 4.9229 0.997 221125_WJC_METTL3_EV_vs_WT_F05.23271.23271.3 0.00189 14/144 K.LYQSAGGMPGGMPGGFPGGGAPPSGGASSGPTIEEVD.- "sp|P11142|HSP7C_HUMAN,tr|E9PNE6|E9PNE6_HUMAN,tr|A8K7Q2|A8K7Q2_HUMAN,tr|E9PKE3|E9PKE3_HUMAN" 4 3345.4918 - 73163 23271 3 3345.479291 1116.1712 Heat shock cognate 71 kDa protein OS=Homo sapiens OX=9606 GN=HSPA8 PE=1 SV=1 3.88 3733.7 - 1.01E+06 - - - -3.7412 - 2.303 0.306 - 77.7 1 2 0 -0.0125 37 0 0 0 - - - - - 3.8674 0.9763 221125_WJC_METTL3_EV_vs_WT_F05.23282.23282.3 0.0195 Sep-80 R.DKLDGNELDLSLSDLNEVPVK.E "sp|Q96AG4|LRC59_HUMAN,tr|I3L223|I3L223_HUMAN" 2 2312.1747 1.89 73168 23282 3 2312.167505 771.7322 Leucine-rich repeat-containing protein 59 OS=Homo sapiens OX=9606 GN=LRRC59 PE=1 SV=1 3.96 3735.1 - 519508 - - - -3.1278 - 1.776 0.289 - 56 1 2 1 -0.0072 21 0 0 0 1.49E+07 7.91E+06 - - - 3.1371 1 221125_WJC_METTL3_EV_vs_WT_F05.23285.23285.4 5.32E-08 24/132 R.SNHEEEVADLLAQIQASHITVER.K "sp|P07197|NFM_HUMAN,tr|E7ESP9|E7ESP9_HUMAN,tr|E7EMV2|E7EMV2_HUMAN" 3 2588.2831 3.68 73169 23285 4 2588.280834 648.078 Neurofilament medium polypeptide OS=Homo sapiens OX=9606 GN=NEFM PE=1 SV=3 4.56 3735.5 - 366481 - - - -0.8593 - 4.287 0.687 - 496.4 1 2 0 -0.0022 23 0 0 0 2.01E+07 5.45E+06 - - - 5.6766 1 221125_WJC_METTL3_EV_vs_WT_F05.23290.23290.3 1.13E-10 16/88 K.SVNDQPSGNLPFLK[136.11]PDDIQYFDK[136.11].L sp|O75533|SF3B1_HUMAN 1 2652.3042 1.26 73172 23290 3 2652.297817 885.1087 Splicing factor 3B subunit 1 OS=Homo sapiens OX=9606 GN=SF3B1 PE=1 SV=3 4.14 3736.2 - 2.39E+06 - - - -2.4247 - 3.368 0.633 - 271.6 1 2 0 -0.0064 23 0 0 0 9.35E+07 7.40E+07 - - - 8.4443 0.9997 221125_WJC_METTL3_EV_vs_WT_F05.23299.23299.3 0.00528 Dec-80 R.DK[136.11]LDGNELDLSLSDLNEVPVK[136.11].E "sp|Q96AG4|LRC59_HUMAN,tr|I3L223|I3L223_HUMAN" 2 2328.2031 1.88 73177 23299 3 2328.204182 777.075 Leucine-rich repeat-containing protein 59 OS=Homo sapiens OX=9606 GN=LRRC59 PE=1 SV=1 3.96 3737.3 - 413856 - - - 0.4488 - 2.404 0.445 - 89.3 1 2 1 0.001 21 0 0 0 1.49E+07 7.91E+06 - - - 5.6039 1 221125_WJC_METTL3_EV_vs_WT_F05.23300.23300.2 6.69E-07 18/38 K.HAASDVDLEIESLLNQQSTK[136.11].E "sp|Q86U44|MTA70_HUMAN,tr|F5H6D8|F5H6D8_HUMAN,tr|H0YFV6|H0YFV6_HUMAN,tr|B4DTN4|B4DTN4_HUMAN" 4 2205.1005 -1 73178 23300 2 2205.093229 1103.5575 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 4.31 3737.4 - 569853 - - - -3.2774 - 4.152 0.734 - 570.8 1 2 0 -0.0072 20 0 0 0 0.00E+00 0.00E+00 - - - 7.96 1 221125_WJC_METTL3_EV_vs_WT_F05.23306.23306.3 2.98E-15 23/88 R.SNHEEEVADLLAQIQASHITVER.K "sp|P07197|NFM_HUMAN,tr|E7ESP9|E7ESP9_HUMAN,tr|E7EMV2|E7EMV2_HUMAN" 3 2588.2831 5.44 73181 23306 3 2588.279815 863.7683 Neurofilament medium polypeptide OS=Homo sapiens OX=9606 GN=NEFM PE=1 SV=3 4.56 3738.1 - 401658 - - - -1.253 - 4.805 0.762 - 632.5 1 2 0 -0.0032 23 0 0 0 7.29E+06 1.34E+06 - - - 10.717 0.9977 221125_WJC_METTL3_EV_vs_WT_F05.23307.23307.4 0.753 Oct-84 R.NLSTVMDEIHTVLKK.D sp|Q8IX12|CCAR1_HUMAN 1 1726.9288 9.88 73182 23307 4 1726.925428 432.7395 Cell division cycle and apoptosis regulator protein 1 OS=Homo sapiens OX=9606 GN=CCAR1 PE=1 SV=2 6.75 3738.3 - 341560 - - - -1.9271 - 1.636 0.28 - 63.6 1 2 0 -0.0033 15 0 0 0 5.47E+06 5.54E+05 - - - 1.8383 1 221125_WJC_METTL3_EV_vs_WT_F05.23313.23313.3 9.90E-09 17/60 K.K[136.11]VSQEILELLNTTTAK[136.11].E "sp|Q86U44|MTA70_HUMAN,tr|H0YFV6|H0YFV6_HUMAN" 2 1803.0324 0 73186 23313 3 1803.026625 602.0181 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 6.14 3739 - 1.61E+06 - - - -3.2196 - 3.658 0.686 - 521.5 1 2 0 -0.0058 16 0 0 0 7.47E+04 1.50E+08 - - - 9.5143 1 221125_WJC_METTL3_EV_vs_WT_F05.23314.23314.4 1.16E-06 11/132 R.RDNYVPEVSALDQEIIEVDPDTK.E "sp|P08708|RS17_HUMAN,tr|H3BNC9|H3BNC9_HUMAN,tr|H0YN88|H0YN88_HUMAN,tr|A0A075B716|A0A075B716_HUMAN" 4 2644.2868 1.75 73187 23314 4 2644.286036 662.079 40S ribosomal protein S17 OS=Homo sapiens OX=9606 GN=RPS17 PE=1 SV=2 3.9 3739.1 - 225432 - - - -0.2912 - 2.473 0.547 - 75.5 1 2 0 -0.0008 23 0 0 0 5.21E+06 2.98E+06 - - - 4.2802 0.9713 221125_WJC_METTL3_EV_vs_WT_F05.23320.23320.4 0.251 8/108 K.SAEKEISLWFKPEELVDYK.S "sp|P22392|NDKB_HUMAN,tr|Q32Q12|Q32Q12_HUMAN" 2 2310.1784 1.21 73191 23320 4 2310.172442 578.5519 Nucleoside diphosphate kinase B OS=Homo sapiens OX=9606 GN=NME2 PE=1 SV=1 4.58 3739.9 - 326508 - - - -2.5639 - 1.476 0.254 - 32.5 1 2 1 -0.0059 19 0 0 0 4.18E+06 3.45E+06 - - - 1.5669 1 221125_WJC_METTL3_EV_vs_WT_F05.23324.23324.4 8.51E-10 24/132 R.SNHEEEVADLLAQIQASHITVER[166.11].K "sp|P07197|NFM_HUMAN,tr|E7ESP9|E7ESP9_HUMAN,tr|E7EMV2|E7EMV2_HUMAN" 3 2598.2913 3.83 73194 23324 4 2598.292177 650.5801 Neurofilament medium polypeptide OS=Homo sapiens OX=9606 GN=NEFM PE=1 SV=3 4.56 3740.4 - 389214 - - - 0.3268 - 4.98 0.668 - 487.6 1 2 0 0.0008 23 0 0 0 2.09E+07 5.45E+06 - - - 5.5602 0.9999 221125_WJC_METTL3_EV_vs_WT_F05.23329.23329.2 1.97E-06 Oct-32 R.STGEAFVQFASQEIAEK[136.11].A "sp|P55795|HNRH2_HUMAN,sp|P31943|HNRH1_HUMAN,tr|E5RGH4|E5RGH4_HUMAN,tr|H0YB39|H0YB39_HUMAN,tr|E5RGV0|E5RGV0_HUMAN,tr|E9PCY7|E9PCY7_HUMAN,tr|D6RIU0|D6RIU0_HUMAN,tr|D6RBM0|D6RBM0_HUMAN,tr|G8JLB6|G8JLB6_HUMAN,tr|E7EN40|E7EN40_HUMAN" 10 1848.8985 0.32 73197 23329 2 1848.897096 925.4565 Heterogeneous nuclear ribonucleoprotein H2 OS=Homo sapiens OX=9606 GN=HNRNPH2 PE=1 SV=1 4.25 3741 - 244697 - - - -0.7642 - 2.496 0.596 - 251 1 2 0 -0.0014 17 0 0 0 3.73E+06 1.18E+07 - - - 5.6914 1 221125_WJC_METTL3_EV_vs_WT_F05.23330.23330.3 2.17E-10 18/64 K.VTLENFYSNLIAQHEER.E sp|Q15208|STK38_HUMAN 1 2062.012 4.48 73198 23330 3 2062.012081 688.3446 Serine\threonine-protein kinase 38 OS=Homo sapiens OX=9606 GN=STK38 PE=1 SV=1 4.75 3741.2 - 392652 - - - 0.0543 - 3.38 0.679 - 443.1 1 2 0 0.0001 17 0 0 0 7.12E+06 1.59E+06 - - - 9.1869 1 221125_WJC_METTL3_EV_vs_WT_F05.23331.23331.2 1.32E-08 Dec-32 R.STGEAFVQFASQEIAEK.A "sp|P55795|HNRH2_HUMAN,sp|P31943|HNRH1_HUMAN,tr|E5RGH4|E5RGH4_HUMAN,tr|H0YB39|H0YB39_HUMAN,tr|E5RGV0|E5RGV0_HUMAN,tr|E9PCY7|E9PCY7_HUMAN,tr|D6RIU0|D6RIU0_HUMAN,tr|D6RBM0|D6RBM0_HUMAN,tr|G8JLB6|G8JLB6_HUMAN,tr|E7EN40|E7EN40_HUMAN" 10 1840.8843 0.35 73199 23331 2 1840.884652 921.4494 Heterogeneous nuclear ribonucleoprotein H2 OS=Homo sapiens OX=9606 GN=HNRNPH2 PE=1 SV=1 4.25 3741.3 - 238894 - - - 0.1863 - 2.817 0.636 - 425.7 1 2 0 0.0003 17 0 0 0 3.59E+06 1.02E+07 - - - 6.2846 0.9993 221125_WJC_METTL3_EV_vs_WT_F05.23332.23332.3 0.00112 Aug-96 R.QTVADQVLVGSYC[160.03]VFSNQGGLVHPK[136.11].T sp|P56537|IF6_HUMAN 1 2710.3628 1.35 73200 23332 3 2710.356785 904.4616 Eukaryotic translation initiation factor 6 OS=Homo sapiens OX=9606 GN=EIF6 PE=1 SV=1 6.73 3741.4 - 193471 - - - -2.2325 - 1.745 0.388 - 60.3 1 2 0 -0.0061 25 0 0 0 2.18E+06 1.62E+06 - - - 4.145 0.9985 221125_WJC_METTL3_EV_vs_WT_F05.23335.23335.3 6.96E-08 13/76 K.NTDKNYLNFVSPLPDIVGQK.S sp|Q9Y2X9|ZN281_HUMAN 1 2261.1692 1.47 73201 23335 3 2261.18115 754.7303 Zinc finger protein 281 OS=Homo sapiens OX=9606 GN=ZNF281 PE=1 SV=1 5.96 3741.8 - 416397 - - - 5.2858 - 3.08 0.554 - 129 1 2 1 0.012 20 0 0 0 1.03E+07 7.02E+06 - - - 7.4423 1 221125_WJC_METTL3_EV_vs_WT_F05.23345.23345.3 4.04E-13 21/76 K.NTDK[136.11]NYLNFVSPLPDIVGQK[136.11].S sp|Q9Y2X9|ZN281_HUMAN 1 2277.1976 1.47 73209 23345 3 2277.201945 760.0731 Zinc finger protein 281 OS=Homo sapiens OX=9606 GN=ZNF281 PE=1 SV=1 5.96 3743.1 - 458164 - - - 1.9089 - 3.827 0.677 - 485.7 1 2 1 0.0043 20 0 0 0 1.03E+07 7.02E+06 - - - 9.3426 0.9998 221125_WJC_METTL3_EV_vs_WT_F05.23349.23349.3 0.000141 Sep-64 R.STGEAFVQFASQEIAEK.A "sp|P55795|HNRH2_HUMAN,sp|P31943|HNRH1_HUMAN,tr|E5RGH4|E5RGH4_HUMAN,tr|H0YB39|H0YB39_HUMAN,tr|E5RGV0|E5RGV0_HUMAN,tr|E9PCY7|E9PCY7_HUMAN,tr|D6RIU0|D6RIU0_HUMAN,tr|D6RBM0|D6RBM0_HUMAN,tr|G8JLB6|G8JLB6_HUMAN,tr|E7EN40|E7EN40_HUMAN" 10 1840.8843 0.81 73213 23349 3 1840.886021 614.6354 Heterogeneous nuclear ribonucleoprotein H2 OS=Homo sapiens OX=9606 GN=HNRNPH2 PE=1 SV=1 4.25 3743.7 - 168572 - - - 0.93 - 1.796 0.43 - 40.8 1 2 0 0.0017 17 0 0 0 1.85E+06 2.29E+06 - - - 4.8129 0.9961 221125_WJC_METTL3_EV_vs_WT_F05.23350.23350.3 0.0265 Aug-64 K.VTLENFYSNLIAQHEER[166.11].E sp|Q15208|STK38_HUMAN 1 2072.0202 4.48 73214 23350 3 2072.020163 691.6807 Serine\threonine-protein kinase 38 OS=Homo sapiens OX=9606 GN=STK38 PE=1 SV=1 4.75 3743.8 - 161325 - - - -0.0367 - 1.526 0.249 - 69.4 1 2 0 -0.0001 17 0 0 0 7.12E+06 1.59E+06 - - - 2.3838 0.9996 221125_WJC_METTL3_EV_vs_WT_F05.23353.23353.3 0.000518 Aug-72 K.ILTATVDNANVLLQIDNAR.L sp|P02533|K1C14_HUMAN 1 2053.1168 999 73217 23353 3 2053.120546 685.3795 "Keratin, type I cytoskeletal 14 OS=Homo sapiens OX=9606 GN=KRT14 PE=1 SV=4" 4.21 3744.2 - 109404 - - - 1.8401 - 1.73 0.411 - 90.9 1 2 0 0.0038 19 0 0 0 1.47E+06 0.00E+00 - - - 4.4678 0.9998 221125_WJC_METTL3_EV_vs_WT_F05.23359.23359.2 0.0205 18-Sep K.ILLAELEQLK[136.11].G "sp|P08670|VIME_HUMAN,tr|B0YJC4|B0YJC4_HUMAN,tr|A0A1B0GTT5|A0A1B0GTT5_HUMAN" 3 1176.7209 2.28 73221 23359 2 1176.721761 589.3677 Vimentin OS=Homo sapiens OX=9606 GN=VIM PE=1 SV=4 4.53 3745 - 165844 - - - 0.7104 - 1.925 0.423 - 184.2 1 2 0 0.0008 10 0 0 0 3.97E+06 1.74E+06 - - - 3.9931 0.9999 221125_WJC_METTL3_EV_vs_WT_F05.23368.23368.4 2.15E-06 13/168 R.RGHAVPPTLVPLMNGSATPLPTALGLGGR.A sp|Q7Z5L9|I2BP2_HUMAN 1 2849.5698 1.7 73228 23368 4 2849.576921 713.3997 Interferon regulatory factor 2-binding protein 2 OS=Homo sapiens OX=9606 GN=IRF2BP2 PE=1 SV=2 12 3746.2 - 154374 - - - 2.4983 - 2.456 0.517 - 60.8 1 2 0 0.0071 29 0 0 0 3.25E+06 1.91E+06 - - - 4.0009 1 221125_WJC_METTL3_EV_vs_WT_F05.23373.23373.3 2.25E-11 17/108 K.TATSLAEGLSLVVSPDSIHSVAPENEGR.L sp|Q9BTV4|TMM43_HUMAN 1 2835.425 2.35 73231 23373 3 2835.42876 946.149 Transmembrane protein 43 OS=Homo sapiens OX=9606 GN=TMEM43 PE=1 SV=1 4.4 3746.9 - 275476 - - - 1.3151 - 3.771 0.677 - 259.2 1 2 0 0.0037 28 0 0 0 3.57E+06 1.52E+06 - - - 9.1406 0.9999 221125_WJC_METTL3_EV_vs_WT_F05.23375.23375.3 0.000303 Oct-76 R.ISLGLPVGAVINC[160.03]ADNTGAK[136.11].N "sp|P62829|RL23_HUMAN,tr|J3KT29|J3KT29_HUMAN,tr|B9ZVP7|B9ZVP7_HUMAN,tr|C9JD32|C9JD32_HUMAN" 4 1977.0445 1.4 73233 23375 3 1977.050007 660.0221 60S ribosomal protein L23 OS=Homo sapiens OX=9606 GN=RPL23 PE=1 SV=1 5.83 3747.2 - 111976 - - - 2.8047 - 2.126 0.526 - 83.2 1 2 0 0.0055 20 0 0 0 1.04E+07 7.44E+06 - - - 6.2327 1 221125_WJC_METTL3_EV_vs_WT_F05.23381.23381.3 2.19E-12 24/116 K.SPEEGAETPVYLALLPPDAEGPHGQFVSEK[136.11].R sp|P16152|CBR1_HUMAN 1 3171.5492 1.83 73237 23381 3 3171.549034 1058.1903 Carbonyl reductase [NADPH] 1 OS=Homo sapiens OX=9606 GN=CBR1 PE=1 SV=3 4.14 3748 - 377694 - - - -0.0448 - 4.381 0.749 - 399.8 1 2 0 -0.0001 30 0 0 0 5.39E+07 2.94E+07 - - - 10.2892 1 221125_WJC_METTL3_EV_vs_WT_F05.23388.23388.3 4.52E-12 23/116 K.SPEEGAETPVYLALLPPDAEGPHGQFVSEK.R sp|P16152|CBR1_HUMAN 1 3163.535 1.85 73242 23388 3 3163.533403 1055.5189 Carbonyl reductase [NADPH] 1 OS=Homo sapiens OX=9606 GN=CBR1 PE=1 SV=3 4.14 3748.9 - 888977 - - - -0.4972 - 4.566 0.718 - 297.7 1 2 0 -0.0016 30 0 0 0 5.26E+07 2.84E+07 - - - 10.0384 1 221125_WJC_METTL3_EV_vs_WT_F05.23389.23389.3 6.74E-12 18/76 R.ISLGLPVGAVINC[160.03]ADNTGAK.N "sp|P62829|RL23_HUMAN,tr|J3KT29|J3KT29_HUMAN,tr|B9ZVP7|B9ZVP7_HUMAN,tr|C9JD32|C9JD32_HUMAN" 4 1969.0303 1.4 73243 23389 3 1969.030899 657.3507 60S ribosomal protein L23 OS=Homo sapiens OX=9606 GN=RPL23 PE=1 SV=1 5.83 3749 - 391752 - - - 0.3235 - 3.365 0.674 - 433.4 1 2 0 0.0006 20 0 0 0 1.04E+07 7.44E+06 - - - 8.9981 1 221125_WJC_METTL3_EV_vs_WT_F05.23390.23390.2 3.17E-07 30-Nov K.HTDESLGDC[160.03]SFLNTC[160.03]F.H "sp|Q86U44|MTA70_HUMAN,tr|H0YFV6|H0YFV6_HUMAN" 2 1901.756 - 73244 23390 2 1901.752516 951.8853 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 4.02 3749.2 - 620331 - - - -1.8394 - 2.471 0.755 - 276.5 1 1 0 -0.0035 16 0 0 0 - - - - - 6.8404 1 221125_WJC_METTL3_EV_vs_WT_F05.23391.23391.2 1.57E-09 14/38 R.ISLGLPVGAVINC[160.03]ADNTGAK.N "sp|P62829|RL23_HUMAN,tr|J3KT29|J3KT29_HUMAN,tr|B9ZVP7|B9ZVP7_HUMAN,tr|C9JD32|C9JD32_HUMAN" 4 1969.0303 1.26 73245 23391 2 1969.028409 985.5224 60S ribosomal protein L23 OS=Homo sapiens OX=9606 GN=RPL23 PE=1 SV=1 5.83 3749.3 - 234822 - - - -0.9411 - 2.801 0.642 - 456 1 2 0 -0.0019 20 0 0 0 8.16E+06 6.48E+06 - - - 6.3145 1 221125_WJC_METTL3_EV_vs_WT_F05.23395.23395.3 1.97E-09 20/104 R.ADHQPLTEASYVNLPTIALC[160.03]NTDSPLR.Y "sp|P08865|RSSA_HUMAN,tr|C9J9K3|C9J9K3_HUMAN,tr|A0A0C4DG17|A0A0C4DG17_HUMAN" 3 2995.4709 0.76 73247 23395 3 2995.465826 999.4976 40S ribosomal protein SA OS=Homo sapiens OX=9606 GN=RPSA PE=1 SV=4 4.54 3749.8 - 640083 - - - -1.7059 - 4.682 0.712 - 257.7 1 2 0 -0.0051 27 0 0 0 2.96E+07 3.87E+07 - - - 10.0282 1 221125_WJC_METTL3_EV_vs_WT_F05.23396.23396.3 9.13E-10 14/104 R.ESGFSYPNFSLPAANGLSSGVGGGGGK[136.11].M sp|P49790|NU153_HUMAN 1 2521.1965 1.41 73248 23396 3 2521.192017 841.4061 Nuclear pore complex protein Nup153 OS=Homo sapiens OX=9606 GN=NUP153 PE=1 SV=2 6.1 3750 - 423578 - - - -1.771 - 2.641 0.603 - 169.5 1 2 0 -0.0045 27 0 0 0 4.54E+07 3.22E+07 - - - 7.4959 1 221125_WJC_METTL3_EV_vs_WT_F05.23400.23400.3 2.90E-17 31/104 R.ADHQPLTEASYVNLPTIALC[160.03]NTDSPLR[166.11].Y "sp|P08865|RSSA_HUMAN,tr|C9J9K3|C9J9K3_HUMAN,tr|A0A0C4DG17|A0A0C4DG17_HUMAN" 3 3005.4792 0.76 73250 23400 3 3005.472245 1002.8337 40S ribosomal protein SA OS=Homo sapiens OX=9606 GN=RPSA PE=1 SV=4 4.54 3750.5 - 1.37E+06 - - - -2.3161 - 5.656 0.711 - 894.6 1 2 0 -0.007 27 0 0 0 2.97E+07 3.89E+07 - - - 10.4514 1 221125_WJC_METTL3_EV_vs_WT_F05.23418.23418.3 1.46E-13 16/96 K.TQQTSPDK[136.11]VDYEYSELLLYQNQVLR[166.11].E "sp|Q9BXJ9|NAA15_HUMAN,tr|A0A0B4J1W3|A0A0B4J1W3_HUMAN" 2 3047.5207 0.04 73260 23418 3 3047.514049 1016.8475 "N-alpha-acetyltransferase 15, NatA auxiliary subunit OS=Homo sapiens OX=9606 GN=NAA15 PE=1 SV=1" 4.32 3753 - 275722 - - - -2.1713 - 3.266 0.734 - 191.7 1 2 1 -0.0066 25 0 0 0 1.04E+05 2.91E+06 - - - 9.4445 1 221125_WJC_METTL3_EV_vs_WT_F05.23421.23421.4 3.43E-07 12/156 R.ADHQPLTEASYVNLPTIALC[160.03]NTDSPLR.Y "sp|P08865|RSSA_HUMAN,tr|C9J9K3|C9J9K3_HUMAN,tr|A0A0C4DG17|A0A0C4DG17_HUMAN" 3 2995.4709 0.82 73263 23421 4 2995.469781 749.875 40S ribosomal protein SA OS=Homo sapiens OX=9606 GN=RPSA PE=1 SV=4 4.54 3753.3 - 232722 - - - -0.3856 - 2.957 0.574 - 77.4 1 2 0 -0.0012 27 0 0 0 3.44E+06 4.20E+06 - - - 4.561 1 221125_WJC_METTL3_EV_vs_WT_F05.23429.23429.3 0.000167 25/76 K.HAASDVDLEIESLLNQQSTK[136.11].E "sp|Q86U44|MTA70_HUMAN,tr|F5H6D8|F5H6D8_HUMAN,tr|H0YFV6|H0YFV6_HUMAN,tr|B4DTN4|B4DTN4_HUMAN" 4 2205.1005 0.02 73267 23429 3 2206.091535 736.0408 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 4.31 3754.4 - 2.73E+06 - - - 449.4485 - 4.157 0.626 - 809.6 1 2 0 0.9911 20 0 0 0 1.01E+07 4.29E+08 - - - 8.7013 0.9978 221125_WJC_METTL3_EV_vs_WT_F05.23430.23430.3 1.78E-07 10/108 S.GTGFNFGIITPTPSSNFTAAQGATPSTK.E "sp|P35658|NU214_HUMAN,tr|A0A0A0MSW3|A0A0A0MSW3_HUMAN,tr|B7ZAV2|B7ZAV2_HUMAN,tr|A0A494C1F2|A0A494C1F2_HUMAN,tr|A0A494C104|A0A494C104_HUMAN,tr|H0Y837|H0Y837_HUMAN" 6 2769.361 2.13 73268 23430 3 2769.35714 924.1276 Nuclear pore complex protein Nup214 OS=Homo sapiens OX=9606 GN=NUP214 PE=1 SV=2 8.75 3754.5 - 216707 - - - -1.3844 - 2.201 0.619 - 66.9 1 1 0 -0.0038 28 0 0 0 2.14E+06 1.00E+06 - - - 7.2552 0.9398 221125_WJC_METTL3_EV_vs_WT_F05.23434.23434.3 0.0279 Jul-64 L.NNPNIPNEIIHALQAGR.L "sp|P52272|HNRPM_HUMAN,tr|A0A087X0X3|A0A087X0X3_HUMAN,tr|M0R2T0|M0R2T0_HUMAN" 3 1869.9809 2.39 73270 23434 3 1869.978472 624.3343 Heterogeneous nuclear ribonucleoprotein M OS=Homo sapiens OX=9606 GN=HNRNPM PE=1 SV=3 6.75 3755 - 215704 - - - -1.3214 - 1.496 0.38 - 35.3 1 1 0 -0.0025 17 0 0 0 3.94E+06 1.65E+06 - - - 3.7935 0.9986 221125_WJC_METTL3_EV_vs_WT_F05.23436.23436.3 0.00614 May-44 R.LFPPQWIC[160.03]C[160.03]DIR[166.11].Y sp|Q86U44|MTA70_HUMAN 1 1613.7722 0 73272 23436 3 1613.771374 538.9313 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 5.82 3755.3 - 104216 - - - -0.518 - 1.129 0.375 - 37 1 2 0 -0.0008 12 0 0 0 1.19E+04 5.17E+06 - - - 3.057 0.8668 221125_WJC_METTL3_EV_vs_WT_F05.23437.23437.2 0.00182 30-Aug K.K[136.11]VSQEILELLNTTTAK[136.11].E "sp|Q86U44|MTA70_HUMAN,tr|H0YFV6|H0YFV6_HUMAN" 2 1803.0324 0.001 73273 23437 2 1804.027823 902.5235 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 6.14 3755.4 - 74740.8 - - - 552.0661 - 1.651 0.491 - 133.9 1 2 0 0.9954 16 0 0 0 0.00E+00 5.75E+06 - - - 3.5876 1 221125_WJC_METTL3_EV_vs_WT_F05.23440.23440.3 1.23E-11 22/104 R.ESGFSYPNFSLPAANGLSSGVGGGGGK.M sp|P49790|NU153_HUMAN 1 2513.1823 1.41 73274 23440 3 2513.184221 838.7347 Nuclear pore complex protein Nup153 OS=Homo sapiens OX=9606 GN=NUP153 PE=1 SV=2 6.1 3755.9 - 1.89E+06 - - - 0.7715 - 3.91 0.687 - 418.9 1 2 0 0.0019 27 0 0 0 4.53E+07 3.22E+07 - - - 9.3358 1 221125_WJC_METTL3_EV_vs_WT_F05.23441.23441.3 3.92E-06 Nov-76 K.DYSQYEENITHLQEQIVDGK.M "sp|Q9C075|K1C23_HUMAN,tr|J3QR55|J3QR55_HUMAN" 2 2408.1132 38.84 73275 23441 3 2408.106224 803.7117 "Keratin, type I cytoskeletal 23 OS=Homo sapiens OX=9606 GN=KRT23 PE=1 SV=2" 4.17 3756 - 317630 - - - -2.8965 - 2.336 0.641 - 73.7 1 2 0 -0.007 20 0 0 0 3.30E+06 8.49E+04 - - - 7.7429 0.9962 221125_WJC_METTL3_EV_vs_WT_F05.23442.23442.3 0.0301 6/104 R.C[160.03]STSLVGQGFVPDGDQVLC[160.03]QGC[160.03]SQAGP.- sp|Q13643|FHL3_HUMAN 1 2823.2262 - 73276 23442 3 2823.224553 942.0827 Four and a half LIM domains protein 3 OS=Homo sapiens OX=9606 GN=FHL3 PE=1 SV=4 3.56 3756.1 - 205972 - - - -0.5883 - 1.226 0.305 - 24.3 1 2 0 -0.0017 27 0 0 0 - - - - - 2.4088 1 221125_WJC_METTL3_EV_vs_WT_F05.23444.23444.3 2.58E-07 Oct-52 R.NHQNLLDSLEQYVK[136.11].G sp|Q93008|USP9X_HUMAN 1 1707.8671 0.62 73278 23444 3 1707.867977 570.2963 Probable ubiquitin carboxyl-terminal hydrolase FAF-X OS=Homo sapiens OX=9606 GN=USP9X PE=1 SV=4 5.32 3756.4 - 156860 - - - 0.4848 - 2.075 0.571 - 145.6 1 2 0 0.0008 14 0 0 0 2.40E+06 3.85E+06 - - - 6.8457 0.9597 221125_WJC_METTL3_EV_vs_WT_F05.23445.23445.3 0.0124 Oct-64 L.NNPNIPNEIIHALQAGR[166.11].L "sp|P52272|HNRPM_HUMAN,tr|A0A087X0X3|A0A087X0X3_HUMAN,tr|M0R2T0|M0R2T0_HUMAN" 3 1879.9892 2.2 73279 23445 3 1879.99051 627.6703 Heterogeneous nuclear ribonucleoprotein M OS=Homo sapiens OX=9606 GN=HNRNPM PE=1 SV=3 6.75 3756.5 - 84500.3 - - - 0.6899 - 1.851 0.35 - 95.8 1 1 0 0.0013 17 0 0 0 1.22E+07 5.57E+06 - - - 3.9973 1 221125_WJC_METTL3_EV_vs_WT_F05.23451.23451.3 2.52E-08 13/76 K.NFGQELAQVQHSIGQLC[160.03]NTK.D "sp|Q15643|TRIPB_HUMAN,tr|H0YJ97|H0YJ97_HUMAN" 2 2271.1066 1.08 73283 23451 3 2271.110662 758.0428 Thyroid receptor-interacting protein 11 OS=Homo sapiens OX=9606 GN=TRIP11 PE=1 SV=3 6.74 3757.3 - 514448 - - - 1.782 - 3.309 0.609 - 119.5 1 2 0 0.004 20 0 0 0 1.52E+07 1.41E+07 - - - 8.2317 0.9996 221125_WJC_METTL3_EV_vs_WT_F05.23457.23457.2 7.47E-05 22-Aug R.LFPPQWIC[160.03]C[160.03]DIR[166.11].Y sp|Q86U44|MTA70_HUMAN 1 1613.7722 0.001 73287 23457 2 1613.775615 807.8934 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 5.82 3758.1 - 378607 - - - 2.11 - 1.753 0.503 - 168.3 1 2 0 0.0034 12 0 0 0 0.00E+00 1.87E+07 - - - 4.232 0.9935 221125_WJC_METTL3_EV_vs_WT_F05.23460.23460.3 0.0124 Jun-52 R.NHQNLLDSLEQYVK.G sp|Q93008|USP9X_HUMAN 1 1699.8529 0.62 73290 23460 3 1699.856676 567.6249 Probable ubiquitin carboxyl-terminal hydrolase FAF-X OS=Homo sapiens OX=9606 GN=USP9X PE=1 SV=4 5.32 3758.5 - 128466 - - - 2.1925 - 1.249 0.308 - 43.7 1 2 0 0.0037 14 0 0 0 2.40E+06 3.85E+06 - - - 2.5637 0.9765 221125_WJC_METTL3_EV_vs_WT_F05.23470.23470.2 1.52 26-Mar K.NSSYFVEWIPNNVK[136.11].T "sp|P04350|TBB4A_HUMAN,sp|Q9BVA1|TBB2B_HUMAN,sp|P07437|TBB5_HUMAN,sp|Q13509|TBB3_HUMAN,sp|Q13885|TBB2A_HUMAN,sp|P68371|TBB4B_HUMAN,sp|Q9BUF5|TBB6_HUMAN,tr|A0A0B4J269|A0A0B4J269_HUMAN,tr|Q5ST81|Q5ST81_HUMAN,tr|Q5JP53|Q5JP53_HUMAN,tr|K7ESM5|K7ESM5_HUMAN" 11 1703.8399 0.56 73298 23470 2 1703.841417 852.9272 Tubulin beta-4A chain OS=Homo sapiens OX=9606 GN=TUBB4A PE=1 SV=2 6 3759.9 - 78554.4 - - - 0.9074 - 0.852 0.212 - 24.4 1 2 0 0.0015 14 0 0 0 9.86E+05 1.78E+06 - - - 0.2044 0.8969 221125_WJC_METTL3_EV_vs_WT_F05.23471.23471.2 0.0807 14-May K.DIGFIK[136.11]LD.- "sp|P62273|RS29_HUMAN,tr|A0A087WTT6|A0A087WTT6_HUMAN" 2 927.5157 1.05 73299 23471 2 927.516465 464.7651 40S ribosomal protein S29 OS=Homo sapiens OX=9606 GN=RPS29 PE=1 SV=2 4.54 3760 - 71518.6 - - - 0.842 - 1.068 0.223 - 50.9 2 2 1 0.0008 8 0 0 0 8.42E+06 8.05E+06 - - - 0.7518 1 221125_WJC_METTL3_EV_vs_WT_F05.23474.23474.4 2.80E-10 18/126 K.TSQLLETLNQLSTHTHVVDITR[166.11].T "sp|Q14203|DCTN1_HUMAN,tr|A0A804CDA6|A0A804CDA6_HUMAN,tr|E7EX90|E7EX90_HUMAN,tr|A0A7P0Z4C3|A0A7P0Z4C3_HUMAN,tr|E7EWF7|E7EWF7_HUMAN" 5 2515.327 1.75 73300 23474 4 2515.331464 629.839 Dynactin subunit 1 OS=Homo sapiens OX=9606 GN=DCTN1 PE=1 SV=3 5.92 3760.6 - 389800 - - - 1.7803 - 3.756 0.567 - 253.1 1 2 0 0.0045 22 0 0 0 6.62E+07 3.78E+07 - - - 4.5929 1 221125_WJC_METTL3_EV_vs_WT_F05.23475.23475.3 2.12E-06 Sep-56 R.DYLHLPPEIVPATLR.R "sp|P46783|RS10_HUMAN,tr|A0A2R8Y6L3|A0A2R8Y6L3_HUMAN,tr|F6U211|F6U211_HUMAN,tr|A0A1W2PQS6|A0A1W2PQS6_HUMAN,tr|A0A2R8YFH6|A0A2R8YFH6_HUMAN,tr|A0A2R8Y7H1|A0A2R8Y7H1_HUMAN,tr|S4R435|S4R435_HUMAN" 7 1732.9512 1.26 73301 23475 3 1732.953986 578.6577 40S ribosomal protein S10 OS=Homo sapiens OX=9606 GN=RPS10 PE=1 SV=1 5.32 3760.7 - 169298 - - - 1.6042 - 2.239 0.516 - 79.4 1 2 0 0.0028 15 0 0 0 7.72E+06 6.14E+06 - - - 6.3953 1 221125_WJC_METTL3_EV_vs_WT_F05.23476.23476.4 3.23E-08 24/126 K.TSQLLETLNQLSTHTHVVDITR.T "sp|Q14203|DCTN1_HUMAN,tr|A0A804CDA6|A0A804CDA6_HUMAN,tr|E7EX90|E7EX90_HUMAN,tr|A0A7P0Z4C3|A0A7P0Z4C3_HUMAN,tr|E7EWF7|E7EWF7_HUMAN" 5 2505.3187 1.75 73302 23476 4 2505.32323 627.337 Dynactin subunit 1 OS=Homo sapiens OX=9606 GN=DCTN1 PE=1 SV=3 5.92 3760.8 - 748917 - - - 1.8018 - 4.579 0.576 - 680.3 1 2 0 0.0045 22 0 0 0 6.54E+07 3.74E+07 - - - 4.7361 0.9998 221125_WJC_METTL3_EV_vs_WT_F05.23484.23484.4 0.000226 6/150 K.SGFEPASLKEEVGEEAIVELVENGKK.V "sp|P35579|MYH9_HUMAN,tr|Q5BKV1|Q5BKV1_HUMAN,tr|B1AH99|B1AH99_HUMAN" 3 2787.4178 1 73308 23484 4 2787.420858 697.8617 Myosin-9 OS=Homo sapiens OX=9606 GN=MYH9 PE=1 SV=4 4.36 3761.9 - 128740 - - - 1.0895 - 1.626 0.475 - 14.5 1 2 1 0.003 26 0 0 0 3.99E+06 3.98E+06 - - - 3.5129 0.9316 221125_WJC_METTL3_EV_vs_WT_F05.23488.23488.2 0.238 14-Aug K.DIGFIKLD.- "sp|P62273|RS29_HUMAN,tr|A0A087WTT6|A0A087WTT6_HUMAN" 2 919.5015 1.05 73310 23488 2 919.501128 460.758 40S ribosomal protein S29 OS=Homo sapiens OX=9606 GN=RPS29 PE=1 SV=2 4.54 3762.4 - 404131 - - - -0.3872 - 1.047 0.236 - 118.7 1 2 1 -0.0004 8 0 0 0 8.42E+06 8.05E+06 - - - 0.9225 1 221125_WJC_METTL3_EV_vs_WT_F05.23489.23489.3 2.00E-07 12/108 K.SGDAAIVDMVPGK[136.11]PMC[160.03]VESFSDYPPLGR[166.11].F "sp|P68104|EF1A1_HUMAN,sp|Q5VTE0|EF1A3_HUMAN,tr|A0A7I2V659|A0A7I2V659_HUMAN,tr|A0A087WVQ9|A0A087WVQ9_HUMAN" 4 3012.415 0.06 73311 23489 3 3012.414043 1005.1456 Elongation factor 1-alpha 1 OS=Homo sapiens OX=9606 GN=EEF1A1 PE=1 SV=1 4.23 3762.5 - 176971 - - - -0.3247 - 2.477 0.668 - 116.6 1 2 0 -0.001 28 0 0 0 2.04E+05 3.32E+06 - - - 8.0741 0.9973 221125_WJC_METTL3_EV_vs_WT_F05.23492.23492.2 0.0368 16-Jul K.EIIDLVLDR.L "sp|Q71U36|TBA1A_HUMAN,sp|P68363|TBA1B_HUMAN,sp|Q9BQE3|TBA1C_HUMAN,tr|F8VS66|F8VS66_HUMAN,tr|F8VRZ4|F8VRZ4_HUMAN,tr|F8VVB9|F8VVB9_HUMAN,tr|A0A1W2PQM2|A0A1W2PQM2_HUMAN,tr|F5H5D3|F5H5D3_HUMAN,tr|F8VQQ4|F8VQQ4_HUMAN" 9 1084.6128 1.65 73314 23492 2 1084.613559 543.3137 Tubulin alpha-1A chain OS=Homo sapiens OX=9606 GN=TUBA1A PE=1 SV=1 4.03 3762.9 - 89916.9 - - - 0.6767 - 1.543 0.186 - 147.7 1 2 0 0.0007 9 0 0 0 1.11E+06 6.72E+05 - - - 1.6694 0.9788 221125_WJC_METTL3_EV_vs_WT_F05.23498.23498.4 0.0087 9/150 K.SGFEPASLK[136.11]EEVGEEAIVELVENGK[136.11]K[136.11].V "sp|P35579|MYH9_HUMAN,tr|Q5BKV1|Q5BKV1_HUMAN,tr|B1AH99|B1AH99_HUMAN" 3 2811.4604 1 73318 23498 4 2811.463991 703.8724 Myosin-9 OS=Homo sapiens OX=9606 GN=MYH9 PE=1 SV=4 4.36 3763.7 - 206315 - - - 1.2698 - 1.922 0.226 - 38.4 1 2 1 0.0036 26 0 0 0 3.99E+06 3.99E+06 - - - 1.3982 0.9979 221125_WJC_METTL3_EV_vs_WT_F05.23503.23503.3 0.0324 8/144 K.LYQSAGGMPGGMPGGFPGGGAPPSGGASSGPTIEEVD.- "sp|P11142|HSP7C_HUMAN,tr|E9PNE6|E9PNE6_HUMAN,tr|A8K7Q2|A8K7Q2_HUMAN,tr|E9PKE3|E9PKE3_HUMAN" 4 3345.4918 - 73322 23503 3 3345.492819 1116.1712 Heat shock cognate 71 kDa protein OS=Homo sapiens OX=9606 GN=HSPA8 PE=1 SV=1 3.88 3764.3 - 318458 - - - 0.3025 - 1.573 0.301 - 25.5 2 2 0 0.001 37 0 0 0 - - - - - 2.7984 0.9942 221125_WJC_METTL3_EV_vs_WT_F05.23508.23508.4 0.0154 4/132 K.SLPEEDVAEIQHAEEFLIKPESK.V "sp|O60832|DKC1_HUMAN,tr|H7C2Q9|H7C2Q9_HUMAN,tr|C9IYT0|C9IYT0_HUMAN,tr|H7C0M1|H7C0M1_HUMAN" 4 2637.3174 1.01 73326 23508 4 2637.319628 660.3366 H\ACA ribonucleoprotein complex subunit DKC1 OS=Homo sapiens OX=9606 GN=DKC1 PE=1 SV=3 4.3 3764.9 - 152858 - - - 0.8531 - 1.332 0.296 - 7.5 5 2 0 0.0022 23 0 0 0 4.04E+06 3.98E+06 - - - 1.3619 0.9999 221125_WJC_METTL3_EV_vs_WT_F05.23512.23512.3 0.00541 Oct-56 R.DYLHLPPEIVPATLR[166.11].R "sp|P46783|RS10_HUMAN,tr|A0A2R8Y6L3|A0A2R8Y6L3_HUMAN,tr|F6U211|F6U211_HUMAN,tr|A0A1W2PQS6|A0A1W2PQS6_HUMAN,tr|A0A2R8YFH6|A0A2R8YFH6_HUMAN,tr|A0A2R8Y7H1|A0A2R8Y7H1_HUMAN,tr|S4R435|S4R435_HUMAN" 7 1742.9595 1.26 73328 23512 3 1742.965211 581.9938 40S ribosomal protein S10 OS=Homo sapiens OX=9606 GN=RPS10 PE=1 SV=1 5.32 3765.5 - 314262 - - - 3.2904 - 2.468 0.516 - 102.3 1 2 0 0.0057 15 0 0 0 7.72E+06 6.14E+06 - - - 6.6486 1 221125_WJC_METTL3_EV_vs_WT_F05.23513.23513.3 1.83E-15 15/100 K.IC[160.03]DFENASK[136.11]PQSIQESTGSIIEVLSK[136.11].L "sp|P51659|DHB4_HUMAN,tr|A0A2R8Y7L2|A0A2R8Y7L2_HUMAN,tr|A0A2R8YD50|A0A2R8YD50_HUMAN,tr|E7ET17|E7ET17_HUMAN,tr|E7ER27|E7ER27_HUMAN,tr|E7EPL9|E7EPL9_HUMAN,tr|A0A804HKU2|A0A804HKU2_HUMAN,tr|A0A804HK65|A0A804HK65_HUMAN" 8 2895.4507 0.08 73329 23513 3 2895.455834 966.1575 Peroxisomal multifunctional enzyme type 2 OS=Homo sapiens OX=9606 GN=HSD17B4 PE=1 SV=3 4.41 3765.6 - 203372 - - - 1.789 - 3.368 0.726 - 213 1 2 0 0.0052 26 0 0 0 2.12E+05 2.50E+06 - - - 9.4265 0.9998 221125_WJC_METTL3_EV_vs_WT_F05.23520.23520.4 0.00188 7/132 K.SLPEEDVAEIQHAEEFLIK[136.11]PESK[136.11].V "sp|O60832|DKC1_HUMAN,tr|H7C2Q9|H7C2Q9_HUMAN,tr|C9IYT0|C9IYT0_HUMAN,tr|H7C0M1|H7C0M1_HUMAN" 4 2653.3458 0.99 73334 23520 4 2653.344814 664.3437 H\ACA ribonucleoprotein complex subunit DKC1 OS=Homo sapiens OX=9606 GN=DKC1 PE=1 SV=3 4.3 3766.5 - 260492 - - - -0.3633 - 1.729 0.39 - 25.8 1 2 0 -0.001 23 0 0 0 3.94E+06 3.98E+06 - - - 2.7977 1 221125_WJC_METTL3_EV_vs_WT_F05.23524.23524.3 4.09E-12 16/92 R.SHELDIDENPASDFDDSGSLLGFK.Y sp|Q96RS0|TGS1_HUMAN 1 2607.1613 1.94 73338 23524 3 2607.1613 870.061 Trimethylguanosine synthase OS=Homo sapiens OX=9606 GN=TGS1 PE=1 SV=3 3.85 3767 - 108918 - - - 0.0107 - 3.342 0.773 - 349.8 1 2 0 0 24 0 0 0 1.30E+06 6.67E+05 - - - 9.9606 0.9974 221125_WJC_METTL3_EV_vs_WT_F05.23532.23532.3 0.0115 May-56 R.QGDTGDWIGTFLGHK.G sp|Q9Y3F4|STRAP_HUMAN 1 1630.774 0.7 73344 23532 3 1630.776675 544.5986 Serine-threonine kinase receptor-associated protein OS=Homo sapiens OX=9606 GN=STRAP PE=1 SV=1 5.21 3768.1 - 119897 - - - 1.6587 - 1.172 0.359 - 29.8 1 2 0 0.0027 15 0 0 0 1.30E+06 1.86E+06 - - - 2.9559 0.9995 221125_WJC_METTL3_EV_vs_WT_F05.23534.23534.3 0.0125 Apr-96 R.SC[160.03]SSSC[160.03]VATDPDSIGAAHLIFC[160.03]C[160.03]FR.D sp|P55000|SLUR1_HUMAN 1 2817.1979 38.24 73346 23534 3 2817.190569 940.0732 Secreted Ly-6\uPAR-related protein 1 OS=Homo sapiens OX=9606 GN=SLURP1 PE=1 SV=2 5.19 3768.4 - 110108 - - - -2.599 - 1.074 0.539 - 9.5 1 2 0 -0.0073 25 0 0 0 1.68E+06 4.39E+04 - - - 4.7115 1 221125_WJC_METTL3_EV_vs_WT_F05.23538.23538.3 1.20E-07 22/84 K.TSQLLETLNQLSTHTHVVDITR.T "sp|Q14203|DCTN1_HUMAN,tr|A0A804CDA6|A0A804CDA6_HUMAN,tr|E7EX90|E7EX90_HUMAN,tr|A0A7P0Z4C3|A0A7P0Z4C3_HUMAN,tr|E7EWF7|E7EWF7_HUMAN" 5 2505.3187 0.36 73349 23538 3 2505.322583 836.1135 Dynactin subunit 1 OS=Homo sapiens OX=9606 GN=DCTN1 PE=1 SV=3 5.92 3768.9 - 272134 - - - 1.5435 - 4.437 0.597 - 738 1 2 0 0.0039 22 0 0 0 1.23E+07 3.47E+07 - - - 8.7274 0.9992 221125_WJC_METTL3_EV_vs_WT_F05.23541.23541.3 0.004 Jun-52 K.AQIHDLVLVGGSTR[166.11].L "sp|P0DMV8|HS71A_HUMAN,sp|P0DMV9|HS71B_HUMAN,tr|V9GZ37|V9GZ37_HUMAN,tr|A0A0G2JIW1|A0A0G2JIW1_HUMAN" 4 1474.8131 0.17 73352 23541 3 1474.814376 492.6117 Heat shock 70 kDa protein 1A OS=Homo sapiens OX=9606 GN=HSPA1A PE=1 SV=1 6.79 3769.3 - 43446.8 - - - 0.834 - 1.343 0.373 - 51.7 1 2 0 0.0012 14 0 0 0 5.44E+05 3.29E+06 - - - 3.482 1 221125_WJC_METTL3_EV_vs_WT_F05.23543.23543.3 0.00165 18/60 K.K[136.11]VSQEILELLNTTTAK[136.11].E "sp|Q86U44|MTA70_HUMAN,tr|H0YFV6|H0YFV6_HUMAN" 2 1803.0324 0 73353 23543 3 1803.03366 602.0181 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 6.14 3769.5 - 725544 - - - 0.6822 - 3.761 0.62 - 639.9 1 2 0 0.0012 16 0 0 0 1.34E+05 6.97E+07 - - - 8.851 0.9972 221125_WJC_METTL3_EV_vs_WT_F05.23557.23557.3 0.00286 Aug-68 R.IGPYQPNVPVGIDYVIPK.T "sp|P43243|MATR3_HUMAN,tr|B3KM87|B3KM87_HUMAN,tr|A8MXP9|A8MXP9_HUMAN,tr|A0A0R4J2E8|A0A0R4J2E8_HUMAN" 4 1968.072 1.31 73364 23557 3 1968.079588 657.0313 Matrin-3 OS=Homo sapiens OX=9606 GN=MATR3 PE=1 SV=2 5.83 3771.4 - 138034 - - - 3.8301 - 1.762 0.363 - 59.1 1 2 0 0.0075 18 0 0 0 4.54E+06 3.45E+06 - - - 3.9955 0.9999 221125_WJC_METTL3_EV_vs_WT_F05.23559.23559.3 2.85E-07 Oct-96 R.C[160.03]SAFPLEQEADLIEAAEPGGPHSSR.N "sp|Q86XL3|ANKL2_HUMAN,tr|F5H1D4|F5H1D4_HUMAN" 2 2667.2235 2.63 73366 23559 3 2667.230775 890.0818 Ankyrin repeat and LEM domain-containing protein 2 OS=Homo sapiens OX=9606 GN=ANKLE2 PE=1 SV=4 4.25 3771.6 - 136734 - - - 2.7294 - 2.421 0.548 - 70 1 2 0 0.0073 25 0 0 0 3.30E+06 1.25E+06 - - - 6.6818 0.9999 221125_WJC_METTL3_EV_vs_WT_F05.23567.23567.3 2.35E-07 Oct-92 R.QQVAPTDDETGKELVLALYDYQEK.S "sp|Q13813|SPTN1_HUMAN,tr|A0A0D9SF54|A0A0D9SF54_HUMAN,tr|A0A0D9SGF6|A0A0D9SGF6_HUMAN" 3 2752.3443 1.49 73372 23567 3 2752.348789 918.4554 "Spectrin alpha chain, non-erythrocytic 1 OS=Homo sapiens OX=9606 GN=SPTAN1 PE=1 SV=3" 4.02 3772.7 - 146609 - - - 1.6233 - 2.292 0.595 - 87.4 1 2 1 0.0045 24 0 0 0 7.16E+06 4.81E+06 - - - 7.0988 1 221125_WJC_METTL3_EV_vs_WT_F05.23568.23568.3 1.22E-10 Dec-80 K.R[166.11]IDTPSLEEPSDLEELEQFAK[136.11].T "sp|P14859|PO2F1_HUMAN,tr|A0A0C4DG88|A0A0C4DG88_HUMAN" 2 2463.2136 1.76 73373 23568 3 2463.220014 822.0785 "POU domain, class 2, transcription factor 1 OS=Homo sapiens OX=9606 GN=POU2F1 PE=1 SV=2" 4 3772.9 - 112198 - - - 2.61 - 3.104 0.614 - 158.1 1 2 0 0.0064 21 0 0 0 7.39E+06 4.20E+06 - - - 8.0993 1 221125_WJC_METTL3_EV_vs_WT_F05.23574.23574.4 1.53E-10 15/174 K.MMVDK[136.11]DGDVTVTNDGATILSMMDVDHQIAK[136.11].L "sp|P48643|TCPE_HUMAN,tr|E9PCA1|E9PCA1_HUMAN,tr|B7ZAR1|B7ZAR1_HUMAN" 3 3265.531 0.45 73377 23574 4 3265.528408 817.39 T-complex protein 1 subunit epsilon OS=Homo sapiens OX=9606 GN=CCT5 PE=1 SV=1 4.11 3773.7 - 269761 - - - -0.7852 - 4.08 0.663 - 100.7 1 2 1 -0.0026 30 0 0 0 2.45E+06 5.40E+06 - - - 5.4263 0.9946 221125_WJC_METTL3_EV_vs_WT_F05.23576.23576.3 0.072 Aug-68 R.IGPYQPNVPVGIDYVIPK[136.11].T "sp|P43243|MATR3_HUMAN,tr|B3KM87|B3KM87_HUMAN,tr|A8MXP9|A8MXP9_HUMAN,tr|A0A0R4J2E8|A0A0R4J2E8_HUMAN" 4 1976.0863 1.31 73379 23576 3 1976.093275 659.7027 Matrin-3 OS=Homo sapiens OX=9606 GN=MATR3 PE=1 SV=2 5.83 3773.9 - 149159 - - - 3.555 - 1.696 0.314 - 55.5 1 2 0 0.007 18 0 0 0 4.57E+06 3.48E+06 - - - 3.3543 0.9926 221125_WJC_METTL3_EV_vs_WT_F05.23578.23578.2 0.00787 Jun-34 R.IGPYQPNVPVGIDYVIPK.T "sp|P43243|MATR3_HUMAN,tr|B3KM87|B3KM87_HUMAN,tr|A8MXP9|A8MXP9_HUMAN,tr|A0A0R4J2E8|A0A0R4J2E8_HUMAN" 4 1968.072 3.09 73381 23578 2 1968.078807 985.0433 Matrin-3 OS=Homo sapiens OX=9606 GN=MATR3 PE=1 SV=2 5.83 3774.2 - 124086 - - - 3.4333 - 1.298 0.344 - 70 1 2 0 0.0068 18 0 0 0 3.24E+06 1.05E+06 - - - 2.2209 1 221125_WJC_METTL3_EV_vs_WT_F05.23583.23583.3 3.69E-10 19/80 K.RIDTPSLEEPSDLEELEQFAK.T "sp|P14859|PO2F1_HUMAN,tr|A0A0C4DG88|A0A0C4DG88_HUMAN" 2 2445.1911 1.76 73384 23583 3 2445.195483 816.071 "POU domain, class 2, transcription factor 1 OS=Homo sapiens OX=9606 GN=POU2F1 PE=1 SV=2" 4 3774.9 - 659662 - - - 1.7864 - 4.086 0.66 - 414 1 2 0 0.0044 21 0 0 0 7.39E+06 4.20E+06 - - - 9.2717 1 221125_WJC_METTL3_EV_vs_WT_F05.23584.23584.3 1.47E-16 24/104 R.ALYDAELSQMQTHISDTSVVLSMDNNR.N "sp|P48668|K2C6C_HUMAN,sp|P04259|K2C6B_HUMAN,sp|P02538|K2C6A_HUMAN" 3 3037.4121 999 73385 23584 3 3037.415219 1013.478 "Keratin, type II cytoskeletal 6C OS=Homo sapiens OX=9606 GN=KRT6C PE=1 SV=3" 4.22 3775 - 604045 - - - 1.0269 - 4.653 0.741 - 589.3 1 2 0 0.0031 27 0 0 0 1.82E+07 0.00E+00 - - - 10.3378 0.9998 221125_WJC_METTL3_EV_vs_WT_F05.23585.23585.4 5.41E-05 12/156 R.ALYDAELSQMQTHISDTSVVLSMDNNR.N "sp|P48668|K2C6C_HUMAN,sp|P04259|K2C6B_HUMAN,sp|P02538|K2C6A_HUMAN" 3 3037.4121 999 73386 23585 4 3037.422797 760.3603 "Keratin, type II cytoskeletal 6C OS=Homo sapiens OX=9606 GN=KRT6C PE=1 SV=3" 4.22 3775.2 - 199843 - - - 3.5217 - 1.92 0.49 - 68.5 1 2 0 0.0107 27 0 0 0 4.09E+06 0.00E+00 - - - 3.6921 1 221125_WJC_METTL3_EV_vs_WT_F05.23586.23586.3 1.99E-08 14/96 R.FQPGETLTEILETPATSEQEAEHQR.A "sp|P46940|IQGA1_HUMAN,tr|H0YLE8|H0YLE8_HUMAN" 2 2840.3464 0.95 73387 23586 3 2840.347372 947.7894 Ras GTPase-activating-like protein IQGAP1 OS=Homo sapiens OX=9606 GN=IQGAP1 PE=1 SV=1 4.2 3775.3 - 145015 - - - 0.3257 - 3.293 0.664 - 147.9 1 2 0 0.0009 25 0 0 0 7.49E+06 7.88E+06 - - - 8.6846 1 221125_WJC_METTL3_EV_vs_WT_F05.23590.23590.3 2.01E-08 16/96 R.FQPGETLTEILETPATSEQEAEHQR[166.11].A "sp|P46940|IQGA1_HUMAN,tr|H0YLE8|H0YLE8_HUMAN" 2 2850.3547 0.95 73389 23590 3 2850.357185 951.1255 Ras GTPase-activating-like protein IQGAP1 OS=Homo sapiens OX=9606 GN=IQGAP1 PE=1 SV=1 4.2 3775.9 - 225279 - - - 0.8659 - 3.406 0.636 - 221.7 1 2 0 0.0025 25 0 0 0 7.45E+06 7.81E+06 - - - 8.4496 0.9999 221125_WJC_METTL3_EV_vs_WT_F05.23615.23615.4 3.75E-06 17/114 K.DHSPDLYSLELAGLDEIGKR.Y "sp|O75787|RENR_HUMAN,tr|B7Z413|B7Z413_HUMAN,tr|A0A1B0GTU8|A0A1B0GTU8_HUMAN,tr|A0A1B0GVI9|A0A1B0GVI9_HUMAN,tr|B7Z1I9|B7Z1I9_HUMAN,tr|A0A1B0GVC7|A0A1B0GVC7_HUMAN,tr|H7C3E1|H7C3E1_HUMAN,tr|A0A1B0GU12|A0A1B0GU12_HUMAN,tr|A0A1C7CYW4|A0A1C7CYW4_HUMAN,tr|A0A1B0GWD6|A0A1B0GWD6_HUMAN,tr|A0A1B0GVB9|A0A1B0GVB9_HUMAN,tr|A0A1B0GWJ8|A0A1B0GWJ8_HUMAN,tr|A0A1B0GVW0|A0A1B0GVW0_HUMAN,tr|A0A1B0GTB0|A0A1B0GTB0_HUMAN" 14 2227.1121 1.18 73405 23615 4 2227.121076 557.7853 Renin receptor OS=Homo sapiens OX=9606 GN=ATP6AP2 PE=1 SV=2 4.43 3779.4 - 160596 - - - 4.0407 - 3.554 0.595 - 328.2 1 2 0 0.009 20 0 0 0 2.35E+06 2.00E+06 - - - 4.8263 0.8204 221125_WJC_METTL3_EV_vs_WT_F05.23617.23617.2 6.53E-05 Jul-52 R.ALYDAELSQMQTHISDTSVVLSMDNNR.N "sp|P48668|K2C6C_HUMAN,sp|P04259|K2C6B_HUMAN,sp|P02538|K2C6A_HUMAN" 3 3037.4121 -1 73407 23617 2 3039.425447 1519.7133 "Keratin, type II cytoskeletal 6C OS=Homo sapiens OX=9606 GN=KRT6C PE=1 SV=3" 4.22 3779.7 - 89327.9 - - - 662.8495 - 1.925 0.533 - 60 1 2 0 2.0133 27 0 0 0 0.00E+00 0.00E+00 - - - 3.9557 0.9988 221125_WJC_METTL3_EV_vs_WT_F05.23628.23628.3 0.0019 Jul-68 R.EGNDLYHEMIESGVINLK.D "sp|P06576|ATPB_HUMAN,tr|F8W079|F8W079_HUMAN,tr|H0YI37|H0YI37_HUMAN,tr|F8W0P7|F8W0P7_HUMAN,tr|H0YH81|H0YH81_HUMAN" 5 2059.9885 1.47 73416 23628 3 2059.994788 687.6701 "ATP synthase subunit beta, mitochondrial OS=Homo sapiens OX=9606 GN=ATP5F1B PE=1 SV=3" 4.4 3781.3 - 73717.8 - - - 3.0738 - 1.604 0.408 - 58.1 1 2 0 0.0063 18 0 0 0 1.22E+06 8.29E+05 - - - 4.2636 0.9989 221125_WJC_METTL3_EV_vs_WT_F05.23629.23629.3 0.000296 7/120 R.SETPPVPPPPPYLASYPGFPENGAPGPPISR.F sp|P48634|PRC2A_HUMAN 1 3184.587 3.96 73417 23629 3 3184.598604 1062.5363 Protein PRRC2A OS=Homo sapiens OX=9606 GN=PRRC2A PE=1 SV=3 4.53 3781.4 - 64045.4 - - - 3.6589 - 1.728 0.439 - 28.1 1 2 0 0.0117 31 0 0 0 1.18E+06 2.98E+05 - - - 4.6896 0.9989 221125_WJC_METTL3_EV_vs_WT_F05.23634.23634.4 7.63E-06 10/144 R.FQPGETLTEILETPATSEQEAEHQR.A "sp|P46940|IQGA1_HUMAN,tr|H0YLE8|H0YLE8_HUMAN" 2 2840.3464 1.35 73420 23634 4 2840.360667 711.0939 Ras GTPase-activating-like protein IQGAP1 OS=Homo sapiens OX=9606 GN=IQGAP1 PE=1 SV=1 4.2 3782.1 - 107033 - - - 5.0064 - 1.994 0.444 - 45.7 1 2 0 0.0142 25 0 0 0 1.65E+06 1.23E+06 - - - 3.3062 0.9857 221125_WJC_METTL3_EV_vs_WT_F05.23635.23635.3 3.76E-07 Sep-72 H.RGDADQASNILASFGLSAR.D "sp|P43243|MATR3_HUMAN,tr|A8MXP9|A8MXP9_HUMAN,tr|D6R991|D6R991_HUMAN,tr|A0A0R4J2E8|A0A0R4J2E8_HUMAN,tr|D6REM6|D6REM6_HUMAN" 5 1947.9763 1.39 73421 23635 3 1947.982953 650.3327 Matrin-3 OS=Homo sapiens OX=9606 GN=MATR3 PE=1 SV=2 5.96 3782.2 - 82016.1 - - - 3.44 - 2.429 0.535 - 91.7 1 1 0 0.0067 19 0 0 0 5.68E+06 4.09E+06 - - - 6.6832 0.9955 221125_WJC_METTL3_EV_vs_WT_F05.23640.23640.3 0.00118 8/100 R.DETSGLHLLPLPESAPALPTEEQVQR.S "sp|P58107|EPIPL_HUMAN,tr|A0A075B730|A0A075B730_HUMAN" 2 2826.44 0.98 73426 23640 3 2826.459435 943.1539 Epiplakin OS=Homo sapiens OX=9606 GN=EPPK1 PE=1 SV=3 4.25 3782.9 - 71014.4 - - - 6.8928 - 1.698 0.505 - 40.7 1 2 0 0.0195 26 0 0 0 3.78E+05 3.86E+05 - - - 5.3829 1 221125_WJC_METTL3_EV_vs_WT_F05.23645.23645.3 5.78E-12 19/72 H.R[166.11]GDADQASNILASFGLSAR[166.11].D "sp|P43243|MATR3_HUMAN,tr|A8MXP9|A8MXP9_HUMAN,tr|D6R991|D6R991_HUMAN,tr|A0A0R4J2E8|A0A0R4J2E8_HUMAN,tr|D6REM6|D6REM6_HUMAN" 5 1967.9928 1.39 73429 23645 3 1967.99882 657.0049 Matrin-3 OS=Homo sapiens OX=9606 GN=MATR3 PE=1 SV=2 5.96 3783.6 - 157857 - - - 3.063 - 4.013 0.682 - 523.4 1 1 0 0.006 19 0 0 0 5.68E+06 4.09E+06 - - - 9.5558 1 221125_WJC_METTL3_EV_vs_WT_F05.23646.23646.3 0.0247 15/76 K.DHSPDLYSLELAGLDEIGKR.Y "sp|O75787|RENR_HUMAN,tr|B7Z413|B7Z413_HUMAN,tr|A0A1B0GTU8|A0A1B0GTU8_HUMAN,tr|A0A1B0GVI9|A0A1B0GVI9_HUMAN,tr|B7Z1I9|B7Z1I9_HUMAN,tr|A0A1B0GVC7|A0A1B0GVC7_HUMAN,tr|H7C3E1|H7C3E1_HUMAN,tr|A0A1B0GU12|A0A1B0GU12_HUMAN,tr|A0A1C7CYW4|A0A1C7CYW4_HUMAN,tr|A0A1B0GWD6|A0A1B0GWD6_HUMAN,tr|A0A1B0GVB9|A0A1B0GVB9_HUMAN,tr|A0A1B0GWJ8|A0A1B0GWJ8_HUMAN,tr|A0A1B0GVW0|A0A1B0GVW0_HUMAN,tr|A0A1B0GTB0|A0A1B0GTB0_HUMAN" 14 2227.1121 1.26 73430 23646 3 2227.113522 743.378 Renin receptor OS=Homo sapiens OX=9606 GN=ATP6AP2 PE=1 SV=2 4.43 3783.7 - 124460 - - - 0.6488 - 2.999 0.516 - 296.2 1 2 0 0.0014 20 0 0 0 4.76E+06 3.77E+06 - - - 6.9569 0.9969 221125_WJC_METTL3_EV_vs_WT_F05.23647.23647.3 0.0103 Aug-60 K.QNDQVSFASLVEELKK.V "sp|Q86UP2|KTN1_HUMAN,tr|G3V4Y7|G3V4Y7_HUMAN,tr|G3V5G2|G3V5G2_HUMAN,tr|H0YJZ8|H0YJZ8_HUMAN" 4 1833.9472 2.61 73431 23647 3 1833.951261 612.323 Kinectin OS=Homo sapiens OX=9606 GN=KTN1 PE=1 SV=1 4.68 3783.8 - 124899 - - - 2.1909 - 1.589 0.299 - 53.6 1 2 0 0.004 16 0 0 0 2.94E+06 1.13E+06 - - - 3.0607 1 221125_WJC_METTL3_EV_vs_WT_F05.23648.23648.3 3.10E-13 14/104 K.VLYDAEISQIHQSVTDTNVILSMDNSR.N sp|P35908|K22E_HUMAN 1 3047.487 9.33 73432 23648 3 3047.49706 1016.8363 "Keratin, type II cytoskeletal 2 epidermal OS=Homo sapiens OX=9606 GN=KRT2 PE=1 SV=2" 4.22 3784 - 114894 - - - 3.3076 - 3.423 0.712 - 135.8 1 2 0 0.0101 27 0 0 0 9.91E+06 1.06E+06 - - - 9.3063 0.9932 221125_WJC_METTL3_EV_vs_WT_F05.23650.23650.3 0.0136 Jul-76 K.DHSPDLYSLELAGLDEIGK[136.11]R[166.11].Y "sp|O75787|RENR_HUMAN,tr|B7Z413|B7Z413_HUMAN,tr|A0A1B0GTU8|A0A1B0GTU8_HUMAN,tr|A0A1B0GVI9|A0A1B0GVI9_HUMAN,tr|B7Z1I9|B7Z1I9_HUMAN,tr|A0A1B0GVC7|A0A1B0GVC7_HUMAN,tr|H7C3E1|H7C3E1_HUMAN,tr|A0A1B0GU12|A0A1B0GU12_HUMAN,tr|A0A1C7CYW4|A0A1C7CYW4_HUMAN,tr|A0A1B0GWD6|A0A1B0GWD6_HUMAN,tr|A0A1B0GVB9|A0A1B0GVB9_HUMAN,tr|A0A1B0GWJ8|A0A1B0GWJ8_HUMAN,tr|A0A1B0GVW0|A0A1B0GVW0_HUMAN,tr|A0A1B0GTB0|A0A1B0GTB0_HUMAN" 14 2245.1345 1.32 73434 23650 3 2246.14023 749.3855 Renin receptor OS=Homo sapiens OX=9606 GN=ATP6AP2 PE=1 SV=2 4.43 3784.2 - 69667.5 - - - 447.9389 - 1.737 0.441 - 52.6 1 2 0 1.0057 20 0 0 0 5.38E+06 4.09E+06 - - - 4.5177 0.9996 221125_WJC_METTL3_EV_vs_WT_F05.23651.23651.3 0.0434 5/108 K.R[166.11]GGGSVVIVSSIAAFSPSPGFSPYNVSK[136.11].T "sp|Q6PKH6|DR4L2_HUMAN,sp|Q9BTZ2|DHRS4_HUMAN,tr|A0A087WSZ6|A0A087WSZ6_HUMAN,tr|A0A087WXI8|A0A087WXI8_HUMAN,tr|H0YKN3|H0YKN3_HUMAN" 5 2784.4565 1.9 73435 23651 3 2784.459346 929.1595 Dehydrogenase\reductase SDR family member 4-like 2 OS=Homo sapiens OX=9606 GN=DHRS4L2 PE=2 SV=2 9.99 3784.4 - 62044.2 - - - 1.0041 - 1.312 0.434 - 12 1 2 0 0.0028 28 0 0 0 9.18E+05 4.83E+05 - - - 4.0026 0.9999 221125_WJC_METTL3_EV_vs_WT_F05.23656.23656.4 0.000125 8/156 K.VLYDAEISQIHQSVTDTNVILSMDNSR.N sp|P35908|K22E_HUMAN 1 3047.487 4.19 73438 23656 4 3047.494803 762.879 "Keratin, type II cytoskeletal 2 epidermal OS=Homo sapiens OX=9606 GN=KRT2 PE=1 SV=2" 4.22 3785 - 212944 - - - 2.567 - 1.828 0.565 - 31.4 1 2 0 0.0078 27 0 0 0 5.47E+06 1.31E+06 - - - 4.3303 0.9996 221125_WJC_METTL3_EV_vs_WT_F05.23658.23658.3 4.00E-05 Dec-56 R.NIETIINTFHQYSVK.L sp|P06702|S10A9_HUMAN 1 1805.9312 421.93 73440 23658 3 1805.936308 602.9843 Protein S100-A9 OS=Homo sapiens OX=9606 GN=S100A9 PE=1 SV=1 6.75 3785.3 - 282046 - - - 2.829 - 2.243 0.398 - 114.2 1 2 0 0.0051 15 0 0 0 7.56E+06 1.79E+04 - - - 5.0838 0.9999 221125_WJC_METTL3_EV_vs_WT_F05.23660.23660.4 1.14E-05 9/114 K.DHSPDLYSLELAGLDEIGK[136.11]R[166.11].Y "sp|O75787|RENR_HUMAN,tr|B7Z413|B7Z413_HUMAN,tr|A0A1B0GTU8|A0A1B0GTU8_HUMAN,tr|A0A1B0GVI9|A0A1B0GVI9_HUMAN,tr|B7Z1I9|B7Z1I9_HUMAN,tr|A0A1B0GVC7|A0A1B0GVC7_HUMAN,tr|H7C3E1|H7C3E1_HUMAN,tr|A0A1B0GU12|A0A1B0GU12_HUMAN,tr|A0A1C7CYW4|A0A1C7CYW4_HUMAN,tr|A0A1B0GWD6|A0A1B0GWD6_HUMAN,tr|A0A1B0GVB9|A0A1B0GVB9_HUMAN,tr|A0A1B0GWJ8|A0A1B0GWJ8_HUMAN,tr|A0A1B0GVW0|A0A1B0GVW0_HUMAN,tr|A0A1B0GTB0|A0A1B0GTB0_HUMAN" 14 2245.1345 1.35 73442 23660 4 2245.140113 562.2909 Renin receptor OS=Homo sapiens OX=9606 GN=ATP6AP2 PE=1 SV=2 4.43 3785.5 - 80607.1 - - - 2.4791 - 2.369 0.538 - 71.9 1 2 0 0.0056 20 0 0 0 2.33E+06 1.73E+06 - - - 4.1956 0.9104 221125_WJC_METTL3_EV_vs_WT_F05.23669.23669.3 0.271 Apr-44 R.LFPPQWIC[160.03]C[160.03]DIR[166.11].Y sp|Q86U44|MTA70_HUMAN 1 1613.7722 0.001 73450 23669 3 1613.773933 538.9313 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 5.82 3786.8 - 100609 - - - 1.0677 - 0.874 0.217 - 21.1 1 2 0 0.0017 12 0 0 0 0.00E+00 1.76E+06 - - - 0.5856 1 221125_WJC_METTL3_EV_vs_WT_F05.23676.23676.3 2.26E-08 9/120 R.SSGGSGGGPLSHFYSGSPTSYFTSGLQAGLK[136.11].Q "tr|K7EQG2|K7EQG2_HUMAN,tr|E9PAU2|E9PAU2_HUMAN,tr|A0A087WZ13|A0A087WZ13_HUMAN" 3 2998.4188 0.73 73455 23676 3 2998.420495 1000.4802 Uncharacterized protein (Fragment) OS=Homo sapiens OX=9606 PE=1 SV=1 8.24 3787.8 - 100211 - - - 0.5553 - 2.571 0.629 - 43.8 1 2 0 0.0017 31 0 0 0 3.86E+06 5.27E+06 - - - 7.7247 0.9997 221125_WJC_METTL3_EV_vs_WT_F05.23678.23678.3 7.73E-10 13/96 K.VEEQEPELTSTPNFVVEVIK[136.11]NDDGK[136.11].K "sp|Q07021|C1QBP_HUMAN,tr|I3L3B0|I3L3B0_HUMAN,tr|I3L3Q7|I3L3Q7_HUMAN" 3 2831.4048 1.05 73457 23678 3 2831.41502 944.8089 "Complement component 1 Q subcomponent-binding protein, mitochondrial OS=Homo sapiens OX=9606 GN=C1QBP PE=1 SV=1" 4 3788 - 88667.4 - - - 3.6272 - 3.178 0.635 - 182 1 2 1 0.0103 25 0 0 0 9.16E+05 8.71E+05 - - - 8.2769 0.9996 221125_WJC_METTL3_EV_vs_WT_F05.23681.23681.2 1.23E-05 22-Aug R.LFPPQWIC[160.03]C[160.03]DIR[166.11].Y sp|Q86U44|MTA70_HUMAN 1 1613.7722 0 73459 23681 2 1613.775851 807.8934 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 5.82 3788.4 - 257761 - - - 2.2562 - 1.691 0.549 - 159.3 1 2 0 0.0036 12 0 0 0 1.57E+04 7.60E+06 - - - 4.477 0.9997 221125_WJC_METTL3_EV_vs_WT_F05.23683.23683.3 1.37E-08 Oct-96 K.VEEQEPELTSTPNFVVEVIKNDDGK.K "sp|Q07021|C1QBP_HUMAN,tr|I3L3B0|I3L3B0_HUMAN,tr|I3L3Q7|I3L3Q7_HUMAN" 3 2815.3764 1.05 73460 23683 3 2815.385689 939.4661 "Complement component 1 Q subcomponent-binding protein, mitochondrial OS=Homo sapiens OX=9606 GN=C1QBP PE=1 SV=1" 4 3788.7 - 154367 - - - 3.3171 - 2.615 0.601 - 87.3 1 2 1 0.0093 25 0 0 0 9.16E+05 8.71E+05 - - - 7.4495 0.8183 221125_WJC_METTL3_EV_vs_WT_F05.23687.23687.2 0.422 28-Apr R.NIETIINTFHQYSVK.L sp|P06702|S10A9_HUMAN 1 1805.9312 999 73464 23687 2 1805.93886 903.9729 Protein S100-A9 OS=Homo sapiens OX=9606 GN=S100A9 PE=1 SV=1 6.75 3789.2 - 40859.5 - - - 4.2421 - 0.855 0.208 - 32.8 1 2 0 0.0077 15 0 0 0 3.86E+05 0.00E+00 - - - 0.1897 0.9684 221125_WJC_METTL3_EV_vs_WT_F05.23722.23722.3 2.59E-05 8/104 R.ESGFSYPNFSLPAANGLSSGVGGGGGK.M sp|P49790|NU153_HUMAN 1 2513.1823 4.05 73488 23722 3 2514.175958 838.7347 Nuclear pore complex protein Nup153 OS=Homo sapiens OX=9606 GN=NUP153 PE=1 SV=2 6.1 3794 - 142917 - - - 395.3856 - 1.895 0.45 - 58.1 1 2 0 0.9937 27 0 0 0 1.50E+06 3.70E+05 - - - 4.7524 0.9432 221125_WJC_METTL3_EV_vs_WT_F05.23729.23729.3 1.64E-06 6/116 T.NTTSNPFGSTSGSLFGPSSFTAAPTGTTIK.F "sp|P52948|NUP98_HUMAN,tr|A0A3B3ITD8|A0A3B3ITD8_HUMAN" 2 2932.409 3.16 73493 23729 3 2932.418869 978.477 Nuclear pore complex protein Nup98-Nup96 OS=Homo sapiens OX=9606 GN=NUP98 PE=1 SV=4 8.75 3794.9 - 58228.2 - - - 3.3495 - 1.279 0.534 - 25.2 1 1 0 0.0098 30 0 0 0 1.07E+06 3.40E+05 - - - 5.057 0.9997 221125_WJC_METTL3_EV_vs_WT_F05.23747.23747.3 0.000177 May-72 K.HVQNQVDEVIDVMQENITK.V sp|O75379|VAMP4_HUMAN 1 2238.095 1.25 73502 23747 3 2238.090267 747.039 Vesicle-associated membrane protein 4 OS=Homo sapiens OX=9606 GN=VAMP4 PE=1 SV=2 4.31 3797.5 - 36967 - - - -2.1357 - 1.197 0.516 - 28.7 1 2 0 -0.0048 19 0 0 0 1.27E+06 1.01E+06 - - - 4.7333 1 221125_WJC_METTL3_EV_vs_WT_F05.23749.23749.3 4.51E-10 9/120 R.SSGGSGGGPLSHFYSGSPTSYFTSGLQAGLK.Q "tr|K7EQG2|K7EQG2_HUMAN,tr|E9PAU2|E9PAU2_HUMAN,tr|A0A087WZ13|A0A087WZ13_HUMAN" 3 2990.4046 0.73 73504 23749 3 2990.40774 997.8088 Uncharacterized protein (Fragment) OS=Homo sapiens OX=9606 PE=1 SV=1 8.24 3797.7 - 94953 - - - 1.04 - 2.141 0.679 - 58.7 1 2 0 0.0031 31 0 0 0 3.84E+06 5.24E+06 - - - 7.8607 0.9984 221125_WJC_METTL3_EV_vs_WT_F05.23762.23762.3 0.000779 Jun-52 K.AQIHDLVLVGGSTR[166.11].L "sp|P0DMV8|HS71A_HUMAN,sp|P0DMV9|HS71B_HUMAN,tr|V9GZ37|V9GZ37_HUMAN,tr|A0A0G2JIW1|A0A0G2JIW1_HUMAN" 4 1474.8131 0.16 73513 23762 3 1474.816901 492.6117 Heat shock 70 kDa protein 1A OS=Homo sapiens OX=9606 GN=HSPA1A PE=1 SV=1 6.79 3799.5 - 45150.8 - - - 2.5461 - 1.532 0.362 - 45.4 1 2 0 0.0038 14 0 0 0 2.29E+05 1.42E+06 - - - 3.7085 0.9993 221125_WJC_METTL3_EV_vs_WT_F05.23764.23764.3 0.0021 6/124 R.NYTQEASLGALQNLTAGSGPMPTSVAQTVVQK.E sp|Q99959|PKP2_HUMAN 1 3260.6347 2.31 73515 23764 3 3260.641062 1087.8855 Plakophilin-2 OS=Homo sapiens OX=9606 GN=PKP2 PE=1 SV=2 6 3799.8 - 56686.9 - - - 1.949 - 1.419 0.422 - 19.9 1 2 0 0.0064 32 0 0 0 6.29E+05 2.73E+05 - - - 4.0482 1 221125_WJC_METTL3_EV_vs_WT_F05.23767.23767.3 2.42E-06 13/60 K.K[136.11]VSQEILELLNTTTAK[136.11].E "sp|Q86U44|MTA70_HUMAN,tr|H0YFV6|H0YFV6_HUMAN" 2 1803.0324 0 73517 23767 3 1803.036617 602.0181 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 6.14 3800.2 - 148346 - - - 2.3222 - 2.962 0.643 - 285.5 1 2 0 0.0042 16 0 0 0 4.46E+04 1.22E+07 - - - 8.4938 0.9912 221125_WJC_METTL3_EV_vs_WT_F05.23783.23783.3 0.0138 Mar-84 R.EHDWNNSISQYTEALNIADYAK.S "sp|Q8IWR0|Z3H7A_HUMAN,tr|I3L382|I3L382_HUMAN,tr|I3L2K5|I3L2K5_HUMAN,tr|I3L1Y3|I3L1Y3_HUMAN" 4 2581.1721 1.3 73526 23783 3 2581.180738 861.398 Zinc finger CCCH domain-containing protein 7A OS=Homo sapiens OX=9606 GN=ZC3H7A PE=1 SV=1 4.31 3802.6 - 33068.6 - - - 3.3423 - 0.853 0.425 - 8.8 1 2 0 0.0086 22 0 0 0 3.83E+05 2.94E+05 - - - 2.899 0.999 221125_WJC_METTL3_EV_vs_WT_F05.23804.23804.4 2.43E-07 8/162 K.HAVSDPSILDSLDLNEDEREVLINNINR.R "sp|P05198|IF2A_HUMAN,tr|H0YJS4|H0YJS4_HUMAN,tr|G3V4T5|G3V4T5_HUMAN" 3 3189.5902 0.28 73539 23804 4 3189.606656 798.4048 Eukaryotic translation initiation factor 2 subunit 1 OS=Homo sapiens OX=9606 GN=EIF2S1 PE=1 SV=3 4.14 3805.2 - 46916.3 - - - 5.1596 - 2.164 0.589 - 32.2 1 2 1 0.0165 28 0 0 0 8.24E+05 2.99E+06 - - - 4.5878 0.9989 221125_WJC_METTL3_EV_vs_WT_F05.23810.23810.3 0.00195 May-80 K.NSTPFMAEHLEETLSAVTNNR.Q "sp|Q9NRA8|4ET_HUMAN,tr|B1AKL4|B1AKL4_HUMAN,tr|B0QYZ7|B0QYZ7_HUMAN" 3 2360.1067 1.97 73543 23810 3 2360.11271 787.7095 Eukaryotic translation initiation factor 4E transporter OS=Homo sapiens OX=9606 GN=EIF4ENIF1 PE=1 SV=2 4.75 3806.1 - 65580.4 - - - 2.5575 - 1.374 0.42 - 18.8 1 2 0 0.006 21 0 0 0 2.43E+06 1.23E+06 - - - 3.9826 1 221125_WJC_METTL3_EV_vs_WT_F05.23837.23837.3 6.37E-06 17/76 K.HAASDVDLEIESLLNQQSTK[136.11].E "sp|Q86U44|MTA70_HUMAN,tr|F5H6D8|F5H6D8_HUMAN,tr|H0YFV6|H0YFV6_HUMAN,tr|B4DTN4|B4DTN4_HUMAN" 4 2205.1005 0 73560 23837 3 2205.102294 736.0408 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 4.31 3809.6 - 322531 - - - 0.8335 - 3.788 0.606 - 346.7 1 2 0 0.0018 20 0 0 0 5.62E+04 2.51E+07 - - - 8.5269 1 221125_WJC_METTL3_EV_vs_WT_F05.23841.23841.4 6.55E-07 11/198 R.K[136.11]PAAGLSAAPVPTAPAAGAPLMDFGNDFVPPAPR[166.11].G "sp|Q9NQC3|RTN4_HUMAN,tr|F8W914|F8W914_HUMAN" 2 3288.7084 0.83 73562 23841 4 3288.707035 823.1844 Reticulon-4 OS=Homo sapiens OX=9606 GN=RTN4 PE=1 SV=2 5.96 3810.2 - 150301 - - - -0.4224 - 2.382 0.539 - 33 1 2 0 -0.0014 34 0 0 0 1.25E+06 1.51E+06 - - - 4.1759 1 221125_WJC_METTL3_EV_vs_WT_F05.23846.23846.3 6.43E-09 13/56 R.HFYWYLTNEGIQYLR.D "sp|P46783|RS10_HUMAN,tr|A0A2R8Y6L3|A0A2R8Y6L3_HUMAN,tr|F6U211|F6U211_HUMAN,tr|A0A1W2PQS6|A0A1W2PQS6_HUMAN,tr|A0A2R8YFH6|A0A2R8YFH6_HUMAN,tr|A0A2R8Y7H1|A0A2R8Y7H1_HUMAN,tr|S4R435|S4R435_HUMAN" 7 2001.9737 1.08 73565 23846 3 2001.969893 668.3319 40S ribosomal protein S10 OS=Homo sapiens OX=9606 GN=RPS10 PE=1 SV=1 6.75 3810.9 - 159662 - - - -1.9181 - 2.766 0.628 - 321.9 1 2 0 -0.0038 15 0 0 0 7.11E+06 6.58E+06 - - - 8.1953 0.9928 221125_WJC_METTL3_EV_vs_WT_F05.23867.23867.2 0.00274 28-Jun K.VSQEILELLNTTTAK.E "sp|Q86U44|MTA70_HUMAN,tr|H0YFV6|H0YFV6_HUMAN" 2 1658.9091 0.01 73576 23867 2 1658.903991 830.4618 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 4.53 3813.6 - 106059 - - - -3.0598 - 1.438 0.28 - 67.1 1 2 0 -0.0051 15 0 0 0 2.12E+06 1.58E+08 - - - 2.0006 0.9696 221125_WJC_METTL3_EV_vs_WT_F05.23869.23869.3 0.000587 Jun-64 K.IELFGR[166.11]PHNVQPNWITL.G sp|Q86U44|MTA70_HUMAN 1 2043.0929 0.01 73578 23869 3 2043.093023 682.0383 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 6.75 3813.8 - 178525 - - - 0.0357 - 1.628 0.4 - 35.5 1 1 0 0.0001 17 0 0 0 9.04E+04 6.74E+06 - - - 4.2308 0.9999 221125_WJC_METTL3_EV_vs_WT_F05.23878.23878.3 6.53E-06 Aug-76 R.NQDLAPNSAEQASILSLVTK.L "sp|Q12905|ILF2_HUMAN,tr|B4DY09|B4DY09_HUMAN,tr|X6R6Z1|X6R6Z1_HUMAN,tr|A0A0A0MRL0|A0A0A0MRL0_HUMAN" 4 2098.0906 0.39 73585 23878 3 2098.092179 700.3708 Interleukin enhancer-binding factor 2 OS=Homo sapiens OX=9606 GN=ILF2 PE=1 SV=2 4.37 3815 - 51339.4 - - - 0.7464 - 1.739 0.531 - 60.3 1 2 0 0.0016 20 0 0 0 1.89E+06 4.89E+06 - - - 5.802 0.9995 221125_WJC_METTL3_EV_vs_WT_F05.23891.23891.3 5.39E-05 Jul-96 K.NIADLMTQAGVEELESENKIPATQK.S sp|O75506|HSBP1_HUMAN 1 2728.3589 1.06 73594 23891 3 2728.358445 910.4603 Heat shock factor-binding protein 1 OS=Homo sapiens OX=9606 GN=HSBP1 PE=1 SV=1 4.25 3816.7 - 81245.8 - - - -0.1763 - 1.5 0.507 - 31.1 1 2 1 -0.0005 25 0 0 0 3.01E+06 2.82E+06 - - - 5.1252 0.9999 221125_WJC_METTL3_EV_vs_WT_F05.23897.23897.4 5.60E-09 11/108 K.GHYTEGAELVDSVLDVVRK.E "sp|Q9BVA1|TBB2B_HUMAN,sp|P07437|TBB5_HUMAN,sp|Q13509|TBB3_HUMAN,sp|Q13885|TBB2A_HUMAN,sp|P68371|TBB4B_HUMAN,tr|A0A0B4J269|A0A0B4J269_HUMAN,tr|Q5ST81|Q5ST81_HUMAN,tr|Q5JP53|Q5JP53_HUMAN,tr|G3V2A3|G3V2A3_HUMAN" 9 2086.0695 0.63 73598 23897 4 2086.078703 522.5246 Tubulin beta-2B chain OS=Homo sapiens OX=9606 GN=TUBB2B PE=1 SV=1 4.75 3817.6 - 85005.8 - - - 4.4193 - 2.21 0.593 - 105.9 1 2 0 0.0092 19 0 0 0 7.74E+06 1.23E+07 - - - 4.6532 0.9999 221125_WJC_METTL3_EV_vs_WT_F05.23903.23903.3 1.68E-07 Sep-72 K.GHYTEGAELVDSVLDVVRK.E "sp|Q9BVA1|TBB2B_HUMAN,sp|P07437|TBB5_HUMAN,sp|Q13509|TBB3_HUMAN,sp|Q13885|TBB2A_HUMAN,sp|P68371|TBB4B_HUMAN,tr|A0A0B4J269|A0A0B4J269_HUMAN,tr|Q5ST81|Q5ST81_HUMAN,tr|Q5JP53|Q5JP53_HUMAN,tr|G3V2A3|G3V2A3_HUMAN" 9 2086.0695 0.52 73601 23903 3 2086.078038 696.3638 Tubulin beta-2B chain OS=Homo sapiens OX=9606 GN=TUBB2B PE=1 SV=1 4.75 3818.5 - 78607.7 - - - 4.1005 - 2.174 0.634 - 104.5 1 2 0 0.0086 19 0 0 0 5.10E+06 9.89E+06 - - - 7.514 1 221125_WJC_METTL3_EV_vs_WT_F05.23933.23933.3 3.99E-10 25/72 K.GHYTEGAELVDSVLDVVR[166.11]K[136.11].E "sp|Q9BVA1|TBB2B_HUMAN,sp|P07437|TBB5_HUMAN,sp|Q13509|TBB3_HUMAN,sp|Q13885|TBB2A_HUMAN,sp|P68371|TBB4B_HUMAN,tr|A0A0B4J269|A0A0B4J269_HUMAN,tr|Q5ST81|Q5ST81_HUMAN,tr|Q5JP53|Q5JP53_HUMAN,tr|G3V2A3|G3V2A3_HUMAN" 9 2104.092 0.52 73617 23933 3 2104.096341 702.3713 Tubulin beta-2B chain OS=Homo sapiens OX=9606 GN=TUBB2B PE=1 SV=1 4.75 3822.5 - 774378 - - - 2.085 - 4.15 0.744 - 929.6 1 2 0 0.0044 19 0 0 0 5.08E+06 9.78E+06 - - - 10.3299 0.999 221125_WJC_METTL3_EV_vs_WT_F05.23941.23941.3 0.00788 Jul-56 K.VSQEILELLNTTTAK[136.11].E "sp|Q86U44|MTA70_HUMAN,tr|H0YFV6|H0YFV6_HUMAN" 2 1666.9233 0.04 73622 23941 3 1666.92645 556.6484 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 4.53 3823.5 - 68525.2 - - - 1.9095 - 1.593 0.359 - 78.2 1 2 0 0.0032 15 0 0 0 9.22E+04 2.30E+06 - - - 3.7566 0.9994 221125_WJC_METTL3_EV_vs_WT_F05.23942.23942.2 8.85E-06 22-Sep R.LFPPQWIC[160.03]C[160.03]DIR[166.11].Y sp|Q86U44|MTA70_HUMAN 1 1613.7722 0.001 73623 23942 2 1613.776741 807.8934 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 5.82 3823.7 - 148370 - - - 2.8077 - 1.853 0.513 - 215.4 1 2 0 0.0045 12 0 0 0 0.00E+00 6.95E+06 - - - 4.4515 0.9863 221125_WJC_METTL3_EV_vs_WT_F05.23944.23944.3 0.142 5/120 R.NTAPAGYQC[160.03]PSC[160.03]NGPIFPPTNLAGPVASALR.E "sp|O95159|ZFPL1_HUMAN,tr|E9PNY1|E9PNY1_HUMAN,tr|E9PQA5|E9PQA5_HUMAN,tr|E9PQ47|E9PQ47_HUMAN" 4 3197.5386 14.39 73625 23944 3 3197.550742 1066.8535 Zinc finger protein-like 1 OS=Homo sapiens OX=9606 GN=ZFPL1 PE=1 SV=2 8.06 3823.9 - 45986.8 - - - 3.7851 - 0.976 0.389 - 15.8 1 2 0 0.0121 31 0 0 0 8.38E+05 5.82E+04 - - - 2.8177 0.9999 221125_WJC_METTL3_EV_vs_WT_F05.23948.23948.3 2.41E-07 13/92 K.QTQIFTTYSDNQPGVLIQVYEGER[166.11].A "sp|P0DMV8|HS71A_HUMAN,sp|P34931|HS71L_HUMAN,sp|P0DMV9|HS71B_HUMAN,tr|Q53FA3|Q53FA3_HUMAN,tr|V9GZ37|V9GZ37_HUMAN,tr|A0A0G2JIW1|A0A0G2JIW1_HUMAN" 6 2795.3642 0.11 73627 23948 3 2795.35946 932.7953 Heat shock 70 kDa protein 1A OS=Homo sapiens OX=9606 GN=HSPA1A PE=1 SV=1 4.14 3824.5 - 157040 - - - -1.681 - 2.679 0.436 - 182.3 1 2 0 -0.0047 24 0 0 0 4.43E+05 3.86E+06 - - - 5.6885 0.9998 221125_WJC_METTL3_EV_vs_WT_F05.23950.23950.3 0.00243 Aug-72 R.SAQGC[160.03]DLLQNLQNITQGAK.L sp|Q9UK39|NOCT_HUMAN 1 2058.0164 1.22 73629 23950 3 2058.016957 687.0127 Nocturnin OS=Homo sapiens OX=9606 GN=NOCT PE=1 SV=2 5.55 3824.8 - 79450.2 - - - 0.2697 - 1.699 0.41 - 68 1 2 0 0.0006 19 0 0 0 8.95E+05 7.34E+05 - - - 4.4131 0.999 221125_WJC_METTL3_EV_vs_WT_F05.23956.23956.2 0.00139 26-Jul K.LVINGNPITIFQER[166.11].D sp|P04406|G3P_HUMAN 1 1622.902 1.09 73633 23956 2 1622.907384 812.4583 Glyceraldehyde-3-phosphate dehydrogenase OS=Homo sapiens OX=9606 GN=GAPDH PE=1 SV=3 6 3825.7 - 70252.1 - - - 3.3415 - 1.835 0.514 - 118.9 1 2 0 0.0054 14 0 0 0 2.30E+06 2.10E+06 - - - 4.359 1 221125_WJC_METTL3_EV_vs_WT_F05.23958.23958.3 3.00E-07 Oct-96 R.DC[160.03]NVILGSAQEFLKPSDSFSAGEPR.V "sp|Q9BRA0|LSMD1_HUMAN,tr|I3L4V0|I3L4V0_HUMAN,tr|A0A0B4J297|A0A0B4J297_HUMAN" 3 2723.2861 2.38 73635 23958 3 2723.283254 908.7693 "N-alpha-acetyltransferase 38, NatC auxiliary subunit OS=Homo sapiens OX=9606 GN=NAA38 PE=1 SV=1" 4.32 3826 - 56415.1 - - - -1.0432 - 2.39 0.623 - 68.8 1 2 0 -0.0028 25 0 0 0 8.42E+05 3.54E+05 - - - 7.4896 0.9986 221125_WJC_METTL3_EV_vs_WT_F05.23971.23971.2 0.000176 26-Jun K.LVINGNPITIFQER.D sp|P04406|G3P_HUMAN 1 1612.8937 1.09 73644 23971 2 1612.898633 807.4541 Glyceraldehyde-3-phosphate dehydrogenase OS=Homo sapiens OX=9606 GN=GAPDH PE=1 SV=3 6 3827.8 - 122140 - - - 3.0641 - 1.565 0.471 - 86.3 1 2 0 0.0049 14 0 0 0 2.30E+06 2.10E+06 - - - 3.6422 0.7788 221125_WJC_METTL3_EV_vs_WT_F05.23979.23979.4 1.14 5/102 R.DGFIDKEDLHDMLASLGK.N "sp|O14950|ML12B_HUMAN,sp|P19105|ML12A_HUMAN,sp|P24844|MYL9_HUMAN,tr|J3KTJ1|J3KTJ1_HUMAN,tr|J3QRS3|J3QRS3_HUMAN" 5 2002.967 1.27 73648 23979 4 2002.974989 501.749 Myosin regulatory light chain 12B OS=Homo sapiens OX=9606 GN=MYL12B PE=1 SV=2 4.35 3828.9 - 92860.3 - - - 3.9926 - 0.812 0.228 - 12.3 1 2 1 0.008 18 0 0 0 1.58E+06 1.24E+06 - - - 1.137 0.9942 221125_WJC_METTL3_EV_vs_WT_F05.23984.23984.4 0.000788 10/210 K.GEAAPGPAPPAPEATPPPASAAGKDWAFINTNIFAR.T "sp|Q9NSI2|SLX9_HUMAN,tr|C9JJU7|C9JJU7_HUMAN" 2 3556.7739 2.33 73651 23984 4 3556.782357 890.2008 Ribosome biogenesis protein SLX9 homolog OS=Homo sapiens OX=9606 GN=SLX9 PE=1 SV=2 4.68 3829.6 - 57318.1 - - - 2.3727 - 2.262 0.313 - 39.6 1 2 1 0.0084 36 0 0 0 5.41E+06 2.32E+06 - - - 2.1886 1 221125_WJC_METTL3_EV_vs_WT_F05.23990.23990.3 3.62E-08 Nov-60 K.K[136.11]VSQEILELLNTTTAK[136.11].E "sp|Q86U44|MTA70_HUMAN,tr|H0YFV6|H0YFV6_HUMAN" 2 1803.0324 0 73656 23990 3 1803.035861 602.0181 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 6.14 3830.5 - 107906 - - - 1.9029 - 2.52 0.66 - 179.3 1 2 0 0.0034 16 0 0 0 9.28E+03 1.21E+07 - - - 8.2689 0.9991 221125_WJC_METTL3_EV_vs_WT_F05.24004.24004.3 2.41E-06 Jul-96 K.LMSSNSTDLPLNIEC[160.03]FMNDK[136.11]DVSGK[136.11].M "sp|Q92598|HS105_HUMAN,tr|A0A0A0MSM0|A0A0A0MSM0_HUMAN" 2 2830.3158 0.02 73664 24004 3 2830.324837 944.4459 Heat shock protein 105 kDa OS=Homo sapiens OX=9606 GN=HSPH1 PE=1 SV=1 4.23 3832.4 - 78646.2 - - - 3.1869 - 1.654 0.572 - 37.7 1 2 1 0.009 25 0 0 0 1.23E+05 6.17E+06 - - - 6.0724 0.9998 221125_WJC_METTL3_EV_vs_WT_F05.24016.24016.3 2.30E-05 Jul-72 K.STNGDTFLGGEDFDQALLR[166.11].H "sp|P38646|GRP75_HUMAN,tr|H0Y8K0|H0Y8K0_HUMAN,tr|A0A7I2V2S7|A0A7I2V2S7_HUMAN,tr|A0A7I2V2G2|A0A7I2V2G2_HUMAN,tr|A0A7I2V3F7|A0A7I2V3F7_HUMAN,tr|A0A7I2YQB2|A0A7I2YQB2_HUMAN,tr|D6RCD7|D6RCD7_HUMAN" 7 2064.9628 0.41 73672 24016 3 2064.967096 689.3282 "Stress-70 protein, mitochondrial OS=Homo sapiens OX=9606 GN=HSPA9 PE=1 SV=2" 3.84 3834 - 25605.6 - - - 2.0887 - 1.732 0.503 - 50.8 1 2 0 0.0043 19 0 0 0 2.57E+05 6.27E+05 - - - 5.4962 0.9106 221125_WJC_METTL3_EV_vs_WT_F05.24021.24021.3 0.000208 4/112 K.APLATGEDDDDEVPDLVENFDEASKNEAN.- "sp|P20290|BTF3_HUMAN,tr|A0A7I2V5Y3|A0A7I2V5Y3_HUMAN" 2 3118.3375 0.91 73674 24021 3 3118.351839 1040.4531 Transcription factor BTF3 OS=Homo sapiens OX=9606 GN=BTF3 PE=1 SV=1 3.42 3834.7 - 57053.4 - - - 4.6118 - 1.118 0.372 - 9.4 1 2 1 0.0144 29 0 0 0 2.47E+06 2.70E+06 - - - 2.9401 0.9985 221125_WJC_METTL3_EV_vs_WT_F05.24022.24022.2 2.50E-05 Apr-36 K.STNGDTFLGGEDFDQALLR[166.11].H "sp|P38646|GRP75_HUMAN,tr|H0Y8K0|H0Y8K0_HUMAN,tr|A0A7I2V2S7|A0A7I2V2S7_HUMAN,tr|A0A7I2V2G2|A0A7I2V2G2_HUMAN,tr|A0A7I2V3F7|A0A7I2V3F7_HUMAN,tr|A0A7I2YQB2|A0A7I2YQB2_HUMAN,tr|D6RCD7|D6RCD7_HUMAN" 7 2064.9628 0.12 73675 24022 2 2064.968314 1033.4887 "Stress-70 protein, mitochondrial OS=Homo sapiens OX=9606 GN=HSPA9 PE=1 SV=2" 3.84 3834.9 - 34475.3 - - - 2.6785 - 1.369 0.463 - 22.5 1 2 0 0.0055 19 0 0 0 7.01E+04 5.88E+05 - - - 3.2312 0.9909 221125_WJC_METTL3_EV_vs_WT_F05.24024.24024.3 0.0713 Jul-72 R.SESELIDELSEDFDR[166.11]SEC[160.03]K[136.11].E "sp|P20810|ICAL_HUMAN,tr|A0A6Q8PG72|A0A6Q8PG72_HUMAN,tr|A0A6Q8PFF6|A0A6Q8PFF6_HUMAN,tr|E7EQA0|E7EQA0_HUMAN,tr|H0YD33|H0YD33_HUMAN,tr|E9PDE4|E9PDE4_HUMAN,tr|B7Z574|B7Z574_HUMAN,tr|A0A6Q8PFE5|A0A6Q8PFE5_HUMAN,tr|A0A6Q8PGN6|A0A6Q8PGN6_HUMAN,tr|H0Y7F0|H0Y7F0_HUMAN,tr|E7EVY3|E7EVY3_HUMAN,tr|H0Y9H6|H0Y9H6_HUMAN,tr|A0A0C4DGB5|A0A0C4DGB5_HUMAN,tr|E9PCH5|E9PCH5_HUMAN,tr|E7ES10|E7ES10_HUMAN,tr|D6RC54|D6RC54_HUMAN,tr|A0A6Q8PGG5|A0A6Q8PGG5_HUMAN,tr|E7EQ12|E7EQ12_HUMAN,tr|A0A6Q8PH20|A0A6Q8PH20_HUMAN" 19 2305.0023 0.59 73677 24024 3 2305.002251 769.3414 Calpastatin OS=Homo sapiens OX=9606 GN=CAST PE=1 SV=4 3.89 3835.1 - 40331.6 - - - -0.0091 - 1.517 0.293 - 45.9 1 2 1 0 19 0 0 0 3.93E+05 6.62E+05 - - - 2.8305 1 221125_WJC_METTL3_EV_vs_WT_F05.24060.24060.3 5.61E-06 7/136 R.VSTSPVGLPSIDPSGSSPSSSSAPLASFSGIPGTR.V "sp|Q8IWZ3|ANKH1_HUMAN,tr|H0Y472|H0Y472_HUMAN,tr|H0Y4P6|H0Y4P6_HUMAN,tr|H7C0V5|H7C0V5_HUMAN,tr|H0Y785|H0Y785_HUMAN" 5 3285.6365 1.64 73696 24060 3 3285.641102 1096.2194 Ankyrin repeat and KH domain-containing protein 1 OS=Homo sapiens OX=9606 GN=ANKHD1 PE=1 SV=1 5.81 3840.4 - 96619.9 - - - 1.4064 - 1.983 0.584 - 19.6 1 2 0 0.0046 35 0 0 0 4.24E+07 2.59E+07 - - - 6.6248 1 221125_WJC_METTL3_EV_vs_WT_F05.24063.24063.3 1.09E-05 10/136 R.VSTSPVGLPSIDPSGSSPSSSSAPLASFSGIPGTR[166.11].V "sp|Q8IWZ3|ANKH1_HUMAN,tr|H0Y472|H0Y472_HUMAN,tr|H0Y4P6|H0Y4P6_HUMAN,tr|H7C0V5|H7C0V5_HUMAN,tr|H0Y785|H0Y785_HUMAN" 5 3295.6448 1.64 73697 24063 3 3295.65041 1099.5555 Ankyrin repeat and KH domain-containing protein 1 OS=Homo sapiens OX=9606 GN=ANKHD1 PE=1 SV=1 5.81 3840.9 - 73965.8 - - - 1.7171 - 2.332 0.582 - 44.5 1 2 0 0.0057 35 0 0 0 4.24E+07 2.59E+07 - - - 6.9752 1 221125_WJC_METTL3_EV_vs_WT_F05.24091.24091.4 2.29E-06 8/204 R.VSTSPVGLPSIDPSGSSPSSSSAPLASFSGIPGTR.V "sp|Q8IWZ3|ANKH1_HUMAN,tr|H0Y472|H0Y472_HUMAN,tr|H0Y4P6|H0Y4P6_HUMAN,tr|H7C0V5|H7C0V5_HUMAN,tr|H0Y785|H0Y785_HUMAN" 5 3285.6365 1.42 73714 24091 4 3285.643519 822.4164 Ankyrin repeat and KH domain-containing protein 1 OS=Homo sapiens OX=9606 GN=ANKHD1 PE=1 SV=1 5.81 3844.8 - 60416.4 - - - 2.1421 - 1.594 0.563 - 27.8 1 2 0 0.007 35 0 0 0 3.10E+06 2.18E+06 - - - 4.2626 0.9991 221125_WJC_METTL3_EV_vs_WT_F05.24097.24097.3 0.000326 Oct-68 K.KGDEVQC[160.03]EIEELGVIINK.V "sp|Q6P2I3|FAH2B_HUMAN,sp|Q96GK7|FAH2A_HUMAN" 2 2072.046 0.99 73718 24097 3 2072.060036 691.6893 Fumarylacetoacetate hydrolase domain-containing protein 2B OS=Homo sapiens OX=9606 GN=FAHD2B PE=1 SV=1 4.25 3845.7 - 70775.7 - - - 6.788 - 2.636 0.568 - 151.8 1 2 0 0.0141 18 0 0 0 2.05E+06 2.07E+06 - - - 7.2823 0.9999 221125_WJC_METTL3_EV_vs_WT_F05.24098.24098.4 0.000284 9/204 R.VSTSPVGLPSIDPSGSSPSSSSAPLASFSGIPGTR[166.11].V "sp|Q8IWZ3|ANKH1_HUMAN,tr|H0Y472|H0Y472_HUMAN,tr|H0Y4P6|H0Y4P6_HUMAN,tr|H7C0V5|H7C0V5_HUMAN,tr|H0Y785|H0Y785_HUMAN" 5 3295.6448 1.42 73719 24098 4 3295.646417 824.9185 Ankyrin repeat and KH domain-containing protein 1 OS=Homo sapiens OX=9606 GN=ANKHD1 PE=1 SV=1 5.81 3845.8 - 76160.2 - - - 0.5055 - 2.319 0.447 - 32.3 1 2 0 0.0017 35 0 0 0 3.10E+06 2.19E+06 - - - 3.3656 0.9997 221125_WJC_METTL3_EV_vs_WT_F05.24100.24100.3 2.71E-10 Dec-68 K.K[136.11]GDEVQC[160.03]EIEELGVIINK[136.11].V "sp|Q6P2I3|FAH2B_HUMAN,sp|Q96GK7|FAH2A_HUMAN" 2 2088.0744 0.99 73721 24100 3 2089.075801 697.0321 Fumarylacetoacetate hydrolase domain-containing protein 2B OS=Homo sapiens OX=9606 GN=FAHD2B PE=1 SV=1 4.25 3846.1 - 60660.6 - - - 479.595 - 2.771 0.672 - 187 1 2 0 1.0014 18 0 0 0 2.05E+06 2.08E+06 - - - 8.2927 0.9999 221125_WJC_METTL3_EV_vs_WT_F05.24108.24108.3 0.000219 16/120 K.ELEQVC[160.03]NPIISGLYQGAGGPGPGGFGAQGPK.G "sp|P0DMV8|HS71A_HUMAN,sp|P0DMV9|HS71B_HUMAN,tr|V9GZ37|V9GZ37_HUMAN,tr|A0A0G2JIW1|A0A0G2JIW1_HUMAN" 4 3054.4869 0.11 73726 24108 3 3054.49958 1019.1696 Heat shock 70 kDa protein 1A OS=Homo sapiens OX=9606 GN=HSPA1A PE=1 SV=1 4.53 3847.2 - 127656 - - - 4.1447 - 3.265 0.607 - 191.6 1 2 0 0.0127 31 0 0 0 3.01E+06 2.77E+07 - - - 8.0262 0.9988 221125_WJC_METTL3_EV_vs_WT_F05.24109.24109.4 0.00166 9/126 R.TIEDAIAVLSVAEEAADR[166.11]HPER[166.11].R sp|Q96CT7|CC124_HUMAN 1 2411.2196 1.27 73727 24109 4 2411.218612 603.8122 Coiled-coil domain-containing protein 124 OS=Homo sapiens OX=9606 GN=CCDC124 PE=1 SV=1 4.35 3847.4 - 69547.6 - - - -0.3919 - 1.589 0.372 - 30.9 1 2 1 -0.0009 22 0 0 0 1.21E+06 9.53E+05 - - - 2.6152 0.9998 221125_WJC_METTL3_EV_vs_WT_F05.24113.24113.4 1.89E-05 7/126 R.TIEDAIAVLSVAEEAADRHPER.R sp|Q96CT7|CC124_HUMAN 1 2391.203 1.21 73729 24113 4 2391.203714 598.808 Coiled-coil domain-containing protein 124 OS=Homo sapiens OX=9606 GN=CCDC124 PE=1 SV=1 4.35 3847.9 - 108191 - - - 0.2915 - 1.752 0.49 - 26.7 1 2 1 0.0007 22 0 0 0 1.25E+06 1.03E+06 - - - 3.6742 1 221125_WJC_METTL3_EV_vs_WT_F05.24114.24114.3 3.10E-13 13/116 K.DPC[160.03]AAPNEGFC[160.03]SAGVQTEAGVADLTWVGER.G sp|Q9BQA1|MEP50_HUMAN 1 3163.3975 4.17 73730 24114 3 3163.401284 1055.4731 Methylosome protein 50 OS=Homo sapiens OX=9606 GN=WDR77 PE=1 SV=1 3.83 3848.1 - 64361 - - - 1.1921 - 2.971 0.806 - 166 1 2 0 0.0038 30 0 0 0 2.58E+06 6.18E+05 - - - 10.0302 0.9999 221125_WJC_METTL3_EV_vs_WT_F05.24115.24115.3 1.90E-08 Aug-64 K.IIHDFPQFYPLGIVQHD.- "sp|P35244|RFA3_HUMAN,tr|B5MC59|B5MC59_HUMAN" 2 2038.0312 - 73731 24115 3 2038.037592 680.351 Replication protein A 14 kDa subunit OS=Homo sapiens OX=9606 GN=RPA3 PE=1 SV=1 5.22 3848.2 - 116637 - - - 3.1128 - 2.143 0.569 - 88.6 1 2 0 0.0063 17 0 0 0 - - - - - 6.8076 0.9997 221125_WJC_METTL3_EV_vs_WT_F05.24116.24116.3 0.00088 Sep-52 R.LHFFMPGFAPLTSR[166.11].G "sp|P04350|TBB4A_HUMAN,sp|Q9BVA1|TBB2B_HUMAN,sp|A6NNZ2|TBB8B_HUMAN,sp|P07437|TBB5_HUMAN,sp|Q13885|TBB2A_HUMAN,sp|P68371|TBB4B_HUMAN,sp|Q9BUF5|TBB6_HUMAN,sp|Q3ZCM7|TBB8_HUMAN,tr|Q5ST81|Q5ST81_HUMAN,tr|Q5JP53|Q5JP53_HUMAN,tr|K7ESM5|K7ESM5_HUMAN,tr|A0A075B736|A0A075B736_HUMAN,tr|Q5SQY0|Q5SQY0_HUMAN" 13 1629.8365 0.61 73732 24116 3 1629.840664 544.2861 Tubulin beta-4A chain OS=Homo sapiens OX=9606 GN=TUBB4A PE=1 SV=2 9.76 3848.3 - 72448.9 - - - 2.5401 - 2.162 0.41 - 117 1 2 0 0.0041 14 0 0 0 6.22E+05 1.02E+06 - - - 5.159 0.9984 221125_WJC_METTL3_EV_vs_WT_F05.24118.24118.4 0.0119 6/108 K.SEDISK[136.11]FDWLDLDPLSK[136.11]PK[136.11].V "sp|O00443|P3C2A_HUMAN,tr|A0A0C4DGF9|A0A0C4DGF9_HUMAN" 2 2256.174 1.38 73734 24118 4 2256.179987 565.0508 Phosphatidylinositol 4-phosphate 3-kinase C2 domain-containing subunit alpha OS=Homo sapiens OX=9606 GN=PIK3C2A PE=1 SV=2 4.36 3848.6 - 60437.3 - - - 2.647 - 1.221 0.414 - 26.7 1 2 1 0.006 19 0 0 0 2.97E+06 2.15E+06 - - - 2.8953 0.9999 221125_WJC_METTL3_EV_vs_WT_F05.24121.24121.4 5.42E-05 11/108 K.SEDISKFDWLDLDPLSKPK.V "sp|O00443|P3C2A_HUMAN,tr|A0A0C4DGF9|A0A0C4DGF9_HUMAN" 2 2232.1314 1.38 73735 24121 4 2232.132668 559.0401 Phosphatidylinositol 4-phosphate 3-kinase C2 domain-containing subunit alpha OS=Homo sapiens OX=9606 GN=PIK3C2A PE=1 SV=2 4.36 3849 - 189019 - - - 0.5613 - 2.167 0.53 - 101 1 2 1 0.0013 19 0 0 0 2.96E+06 2.15E+06 - - - 4.1004 0.9999 221125_WJC_METTL3_EV_vs_WT_F05.24123.24123.3 2.83E-05 Aug-76 R.DHSTPETLSIMDDLISSPGK[136.11].N sp|Q9C091|GRB1L_HUMAN 1 2150.0293 0.93 73737 24123 3 2150.032825 717.6837 GREB1-like protein OS=Homo sapiens OX=9606 GN=GREB1L PE=1 SV=2 4.22 3849.3 - 46175.2 - - - 1.6558 - 1.527 0.584 - 44.4 1 2 0 0.0036 20 0 0 0 5.33E+05 5.75E+05 - - - 6.077 0.9877 221125_WJC_METTL3_EV_vs_WT_F05.24128.24128.2 5.23E-05 22-Oct K.K[136.11]VSQEILELLNT.T "sp|Q86U44|MTA70_HUMAN,tr|H0YFV6|H0YFV6_HUMAN" 2 1393.7908 0.001 73740 24128 2 1393.792388 697.9027 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 4.53 3850 - 179775 - - - 1.1422 - 2.044 0.489 - 365 1 1 0 0.0016 12 0 0 0 0.00E+00 3.96E+06 - - - 4.5333 0.9999 221125_WJC_METTL3_EV_vs_WT_F05.24129.24129.3 3.32E-07 Sep-72 K.SEDISKFDWLDLDPLSKPK.V "sp|O00443|P3C2A_HUMAN,tr|A0A0C4DGF9|A0A0C4DGF9_HUMAN" 2 2232.1314 2.14 73741 24129 3 2232.133823 745.0511 Phosphatidylinositol 4-phosphate 3-kinase C2 domain-containing subunit alpha OS=Homo sapiens OX=9606 GN=PIK3C2A PE=1 SV=2 4.36 3850.1 - 105434 - - - 1.0788 - 2.302 0.635 - 93.6 1 2 1 0.0024 19 0 0 0 1.04E+06 4.87E+05 - - - 7.6674 1 221125_WJC_METTL3_EV_vs_WT_F05.24130.24130.4 4.66E-10 18/180 K.ELEQVC[160.03]NPIISGLYQGAGGPGPGGFGAQGPK[136.11].G "sp|P0DMV8|HS71A_HUMAN,sp|P0DMV9|HS71B_HUMAN,tr|V9GZ37|V9GZ37_HUMAN,tr|A0A0G2JIW1|A0A0G2JIW1_HUMAN" 4 3062.5011 0.04 73742 24130 4 3062.504259 766.6326 Heat shock 70 kDa protein 1A OS=Homo sapiens OX=9606 GN=HSPA1A PE=1 SV=1 4.53 3850.2 - 202114 - - - 1.025 - 3.55 0.586 - 163.3 1 2 0 0.0031 31 0 0 0 1.08E+05 2.89E+06 - - - 4.7107 1 221125_WJC_METTL3_EV_vs_WT_F05.24154.24154.3 2.26E-08 12/112 K.SIDDTSNFDDFPESDILQPVPNTTEPDYK.S sp|Q9Y2H1|ST38L_HUMAN 1 3298.4677 4.71 73758 24154 3 3298.472364 1100.4965 Serine\threonine-protein kinase 38-like OS=Homo sapiens OX=9606 GN=STK38L PE=1 SV=3 3.5 3853.6 - 179156 - - - 1.4007 - 2.223 0.655 - 68.5 1 2 0 0.0046 29 0 0 0 1.91E+07 4.05E+06 - - - 7.6792 0.9966 221125_WJC_METTL3_EV_vs_WT_F05.24170.24170.3 0.0671 5/104 K.KPADIPQGSLAYLEQASANIPAPLKPT.- "sp|Q9H204|MED28_HUMAN,tr|H0YAA8|H0YAA8_HUMAN" 2 2789.4963 2.21 73769 24170 3 2789.504206 930.8394 Mediator of RNA polymerase II transcription subunit 28 OS=Homo sapiens OX=9606 GN=MED28 PE=1 SV=1 6.07 3855.8 - 32545.8 - - - 2.8177 - 1.063 0.415 - 10.5 1 2 0 0.0079 27 0 0 0 1.94E+06 8.76E+05 - - - 3.3052 0.9938 221125_WJC_METTL3_EV_vs_WT_F05.24190.24190.2 0.00216 24-Jun K.TLNDELEIIEGMK[136.11].F "sp|P10809|CH60_HUMAN,tr|A0A7I2V2X6|A0A7I2V2X6_HUMAN,tr|A0A7I2V599|A0A7I2V599_HUMAN,tr|E7EXB4|E7EXB4_HUMAN,tr|A0A7I2YQ71|A0A7I2YQ71_HUMAN,tr|E7ESH4|E7ESH4_HUMAN,tr|A0A7I2V5M1|A0A7I2V5M1_HUMAN,tr|A0A7I2V5K3|A0A7I2V5K3_HUMAN,tr|A0A7I2V369|A0A7I2V369_HUMAN" 9 1511.7633 1.32 73780 24190 2 1511.768929 756.8889 "60 kDa heat shock protein, mitochondrial OS=Homo sapiens OX=9606 GN=HSPD1 PE=1 SV=2" 4 3858.6 - 44205.8 - - - 3.7493 - 1.418 0.36 - 65.8 1 2 0 0.0057 13 0 0 0 2.51E+06 1.91E+06 - - - 2.5945 1 221125_WJC_METTL3_EV_vs_WT_F05.24204.24204.3 3.95E-08 Dec-60 K.K[136.11]VSQEILELLNTTTAK[136.11].E "sp|Q86U44|MTA70_HUMAN,tr|H0YFV6|H0YFV6_HUMAN" 2 1803.0324 0.001 73787 24204 3 1803.036095 602.0181 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 6.14 3860.6 - 99704.6 - - - 2.0327 - 2.641 0.663 - 233.3 1 2 0 0.0037 16 0 0 0 0.00E+00 4.51E+06 - - - 8.4226 0.9994 221125_WJC_METTL3_EV_vs_WT_F05.24209.24209.3 0.000995 Jun-88 K.TGIASSILDAISQGSESQHALEK.C sp|Q9HCJ3|RAVR2_HUMAN 1 2341.1761 1.54 73790 24209 3 2341.182505 781.3993 Ribonucleoprotein PTB-binding 2 OS=Homo sapiens OX=9606 GN=RAVER2 PE=1 SV=2 4.65 3861.4 - 92097.8 - - - 2.7213 - 1.831 0.412 - 23 1 2 0 0.0064 23 0 0 0 1.37E+07 8.89E+06 - - - 4.5506 0.9995 221125_WJC_METTL3_EV_vs_WT_F05.24219.24219.3 2.51E-06 9/112 K.QEPSSPPLAPGLPAFLAAPGTTSC[160.03]PEC[160.03]GK.T sp|Q8N0Y2|ZN444_HUMAN 1 2936.4048 3.29 73798 24219 3 2936.417903 979.8089 Zinc finger protein 444 OS=Homo sapiens OX=9606 GN=ZNF444 PE=1 SV=1 4.53 3862.6 - 49349.4 - - - 4.452 - 2.008 0.535 - 43.8 1 2 0 0.0131 29 0 0 0 3.09E+06 9.37E+05 - - - 6.105 0.9989 221125_WJC_METTL3_EV_vs_WT_F05.24225.24225.3 0.018 Aug-76 R.ER[166.11]TAADELEAFLGGGAPGGR[166.11].H sp|Q3YEC7|RABL6_HUMAN 1 1992.9768 0.34 73802 24225 3 1992.980222 665.3329 Rab-like protein 6 OS=Homo sapiens OX=9606 GN=RABL6 PE=1 SV=2 4.41 3863.4 - 32369 - - - 1.713 - 1.845 0.431 - 59.3 1 2 1 0.0034 20 0 0 0 3.07E+05 8.90E+05 - - - 4.8302 0.999 221125_WJC_METTL3_EV_vs_WT_F05.24231.24231.3 0.0561 May-60 R.LQQELDDLLVDLDHQR[166.11].Q sp|P35579|MYH9_HUMAN 1 1958.9937 0.86 73805 24231 3 1958.991188 654.0052 Myosin-9 OS=Homo sapiens OX=9606 GN=MYH9 PE=1 SV=4 4.03 3864.2 - 61773.4 - - - -1.2772 - 1.124 0.407 - 34.1 1 2 0 -0.0025 16 0 0 0 6.99E+05 8.08E+05 - - - 3.3769 0.9998 221125_WJC_METTL3_EV_vs_WT_F05.24232.24232.3 0.00497 Dec-88 K.TGIASSILDAISQGSESQHALEK[136.11].C sp|Q9HCJ3|RAVR2_HUMAN 1 2349.1903 1.62 73806 24232 3 2349.192545 784.0707 Ribonucleoprotein PTB-binding 2 OS=Homo sapiens OX=9606 GN=RAVER2 PE=1 SV=2 4.65 3864.3 - 372057 - - - 0.9412 - 2.634 0.356 - 128.3 1 2 0 0.0022 23 0 0 0 1.48E+07 9.13E+06 - - - 4.7805 0.9992 221125_WJC_METTL3_EV_vs_WT_F05.24236.24236.2 1.15E-06 22-Aug R.AQFEGIVTDLIR[166.11].R "sp|P38646|GRP75_HUMAN,tr|H0Y8K0|H0Y8K0_HUMAN,tr|A0A7I2V2S7|A0A7I2V2S7_HUMAN,tr|A0A7I2V2G2|A0A7I2V2G2_HUMAN,tr|A0A7I2V3F7|A0A7I2V3F7_HUMAN,tr|A0A7I2YQB2|A0A7I2YQB2_HUMAN,tr|D6RCD7|D6RCD7_HUMAN" 7 1370.7433 0.33 73810 24236 2 1370.748157 686.3789 "Stress-70 protein, mitochondrial OS=Homo sapiens OX=9606 GN=HSPA9 PE=1 SV=2" 4.37 3864.8 - 35589.9 - - - 3.5178 - 1.686 0.6 - 198.3 1 2 0 0.0048 12 0 0 0 2.31E+05 7.04E+05 - - - 4.8455 0.9761 221125_WJC_METTL3_EV_vs_WT_F05.24238.24238.2 0.0322 18-Apr K.LLEPVLLLGK.E "sp|P62249|RS16_HUMAN,tr|M0R210|M0R210_HUMAN,tr|M0R3H0|M0R3H0_HUMAN,tr|M0QX76|M0QX76_HUMAN,tr|M0R1M5|M0R1M5_HUMAN,tr|Q6IPX4|Q6IPX4_HUMAN" 6 1093.7111 0.94 73812 24238 2 1093.713882 547.8628 40S ribosomal protein S16 OS=Homo sapiens OX=9606 GN=RPS16 PE=1 SV=2 6 3865.1 - 22925 - - - 2.5592 - 0.969 0.256 - 40.8 1 2 0 0.0028 10 0 0 0 9.51E+05 1.01E+06 - - - 0.843 0.9967 221125_WJC_METTL3_EV_vs_WT_F05.24255.24255.4 0.0126 Jul-96 R.THNLEPYFESFINNLRR.R sp|P04264|K2C1_HUMAN 1 2149.0705 574.59 73822 24255 4 2149.074904 538.2749 "Keratin, type II cytoskeletal 1 OS=Homo sapiens OX=9606 GN=KRT1 PE=1 SV=6" 6.42 3867.6 - 46084.3 - - - 2.0553 - 1.415 0.278 - 27.4 1 2 0 0.0044 17 0 0 0 3.85E+07 6.70E+04 - - - 1.765 1 221125_WJC_METTL3_EV_vs_WT_F05.24261.24261.3 3.62E-10 20/76 K.HAASDVDLEIESLLNQQSTK[136.11].E "sp|Q86U44|MTA70_HUMAN,tr|F5H6D8|F5H6D8_HUMAN,tr|H0YFV6|H0YFV6_HUMAN,tr|B4DTN4|B4DTN4_HUMAN" 4 2205.1005 0.01 73825 24261 3 2206.104322 736.0408 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 4.31 3868.4 - 189808 - - - 455.2473 - 3.737 0.667 - 519.1 1 2 0 1.0039 20 0 0 0 6.92E+04 7.53E+06 - - - 8.8965 0.9985 221125_WJC_METTL3_EV_vs_WT_F05.24264.24264.3 4.56E-06 9/112 K.QEPSSPPLAPGLPAFLAAPGTTSC[160.03]PEC[160.03]GK[136.11].T sp|Q8N0Y2|ZN444_HUMAN 1 2944.419 3.26 73827 24264 3 2944.439362 982.4803 Zinc finger protein 444 OS=Homo sapiens OX=9606 GN=ZNF444 PE=1 SV=1 4.53 3868.8 - 60313.7 - - - 6.9053 - 1.929 0.588 - 35.8 1 2 0 0.0203 29 0 0 0 3.05E+06 9.37E+05 - - - 6.6015 0.9998 221125_WJC_METTL3_EV_vs_WT_F05.24297.24297.3 1.07E-05 7/120 K.AFLADPSAFVAAAPVAAATTAAPAAAAAPAK.V "sp|P05388|RLA0_HUMAN,tr|F8VWS0|F8VWS0_HUMAN,tr|F8W1K8|F8W1K8_HUMAN" 3 2751.4596 1.8 73841 24297 3 2751.466619 918.1605 60S acidic ribosomal protein P0 OS=Homo sapiens OX=9606 GN=RPLP0 PE=1 SV=1 5.88 3873.7 - 31879 - - - 2.5634 - 1.788 0.506 - 28 1 2 0 0.0071 31 0 0 0 9.99E+05 5.56E+05 - - - 5.5163 0.9981 221125_WJC_METTL3_EV_vs_WT_F05.24308.24308.3 1.08E-06 8/108 K.TPSTMENDSSNLDPSQAPSLAQPLVFSN.S "sp|Q14157|UBP2L_HUMAN,tr|F8W726|F8W726_HUMAN,tr|Q5VU77|Q5VU77_HUMAN" 3 2946.3553 - 73846 24308 3 2946.356577 983.1257 Ubiquitin-associated protein 2-like OS=Homo sapiens OX=9606 GN=UBAP2L PE=1 SV=2 3.49 3875.3 - 81010.8 - - - 0.4344 - 1.912 0.645 - 44.9 1 1 0 0.0013 28 0 0 0 - - - - - 7.2219 0.9947 221125_WJC_METTL3_EV_vs_WT_F05.24309.24309.3 0.000302 Jul-80 R.ESEEENLNKSEISQVFEIALK.R "sp|O95793|STAU1_HUMAN,tr|Q5JW30|Q5JW30_HUMAN,tr|Q5JW28|Q5JW28_HUMAN" 3 2435.2068 2.09 73847 24309 3 2435.214525 812.7429 Double-stranded RNA-binding protein Staufen homolog 1 OS=Homo sapiens OX=9606 GN=STAU1 PE=1 SV=2 4.21 3875.4 - 141574 - - - 3.1866 - 1.768 0.397 - 53.3 1 2 1 0.0078 21 0 0 0 3.21E+06 1.53E+06 - - - 4.3302 0.9994 221125_WJC_METTL3_EV_vs_WT_F05.24318.24318.3 0.0063 5/120 K.AFLADPSAFVAAAPVAAATTAAPAAAAAPAK[136.11].V "sp|P05388|RLA0_HUMAN,tr|F8VWS0|F8VWS0_HUMAN,tr|F8W1K8|F8W1K8_HUMAN" 3 2759.4738 1.8 73854 24318 3 2759.474799 920.8319 60S acidic ribosomal protein P0 OS=Homo sapiens OX=9606 GN=RPLP0 PE=1 SV=1 5.88 3876.7 - 34865.6 - - - 0.3743 - 1.512 0.379 - 18.8 1 2 0 0.001 31 0 0 0 9.99E+05 5.56E+05 - - - 3.7163 0.9926 221125_WJC_METTL3_EV_vs_WT_F05.24326.24326.3 2.96E-08 Nov-60 V.RQNLEPLFEQYINNLR.R "sp|P48668|K2C6C_HUMAN,sp|P04259|K2C6B_HUMAN,sp|P13647|K2C5_HUMAN,sp|P02538|K2C6A_HUMAN,tr|F8W0C6|F8W0C6_HUMAN" 5 2046.0647 412.88 73859 24326 3 2046.071693 683.0288 "Keratin, type II cytoskeletal 6C OS=Homo sapiens OX=9606 GN=KRT6C PE=1 SV=3" 6.14 3877.7 - 40814.8 - - - 3.431 - 2.495 0.61 - 196.7 1 1 0 0.007 16 0 0 0 6.88E+06 1.67E+04 - - - 7.6849 0.8737 221125_WJC_METTL3_EV_vs_WT_F05.24331.24331.3 0.0555 Mar-80 R.ESEEENLNK[136.11]SEISQVFEIALK[136.11].R "sp|O95793|STAU1_HUMAN,tr|Q5JW30|Q5JW30_HUMAN,tr|Q5JW28|Q5JW28_HUMAN" 3 2451.2352 2.09 73860 24331 3 2451.235895 818.0857 Double-stranded RNA-binding protein Staufen homolog 1 OS=Homo sapiens OX=9606 GN=STAU1 PE=1 SV=2 4.21 3878.4 - 75237.8 - - - 0.2978 - 0.951 0.257 - 6.3 2 2 1 0.0007 21 0 0 0 3.21E+06 1.53E+06 - - - 1.1453 0.9558 221125_WJC_METTL3_EV_vs_WT_F05.24336.24336.4 1.81 5/114 K.LSSSIIHEIDSILGNKPYSK.K "sp|Q13303|KCAB2_HUMAN,tr|A0A5F9UN28|A0A5F9UN28_HUMAN,tr|A0A590UJB6|A0A590UJB6_HUMAN" 3 2200.1739 1.96 73862 24336 4 2200.177578 551.0508 Voltage-gated potassium channel subunit beta-2 OS=Homo sapiens OX=9606 GN=KCNAB2 PE=1 SV=2 6.75 3879.1 - 59083.7 - - - 1.6494 - 0.904 0.204 - 7.7 2 2 0 0.0036 20 0 0 0 6.93E+06 3.53E+06 - - - 0.7374 0.857 221125_WJC_METTL3_EV_vs_WT_F05.24337.24337.3 0.199 Jul-76 K.LSSSIIHEIDSILGNK[136.11]PYSK[136.11].K "sp|Q13303|KCAB2_HUMAN,tr|A0A5F9UN28|A0A5F9UN28_HUMAN,tr|A0A590UJB6|A0A590UJB6_HUMAN" 3 2216.2023 2.12 73863 24337 3 2216.207952 739.7414 Voltage-gated potassium channel subunit beta-2 OS=Homo sapiens OX=9606 GN=KCNAB2 PE=1 SV=2 6.75 3879.3 - 13655.1 - - - 2.5282 - 1.112 0.178 - 39.4 1 2 0 0.0056 20 0 0 0 2.90E+06 1.37E+06 - - - 0.7805 0.9973 221125_WJC_METTL3_EV_vs_WT_F05.24347.24347.3 0.00247 13/64 R.THNLEPYFESFINNLRR.R sp|P04264|K2C1_HUMAN 1 2149.0705 679.75 73868 24347 3 2149.069813 717.3641 "Keratin, type II cytoskeletal 1 OS=Homo sapiens OX=9606 GN=KRT1 PE=1 SV=6" 6.42 3880.7 - 595330 - - - -0.3136 - 2.406 0.168 - 186.6 1 2 0 -0.0007 17 0 0 0 2.54E+07 3.73E+04 - - - 2.6309 0.9804 221125_WJC_METTL3_EV_vs_WT_F05.24349.24349.4 0.00957 Jun-90 K.STSESFIQHIVSLVHH.V "sp|Q9NYF8|BCLF1_HUMAN,tr|E9PKI6|E9PKI6_HUMAN,tr|A0A1W2PQ43|A0A1W2PQ43_HUMAN,tr|E9PK91|E9PK91_HUMAN,tr|E9PJA7|E9PJA7_HUMAN,tr|E9PK09|E9PK09_HUMAN,tr|E9PQN2|E9PQN2_HUMAN" 7 1819.9217 - 73869 24349 4 1819.923502 455.9877 Bcl-2-associated transcription factor 1 OS=Homo sapiens OX=9606 GN=BCLAF1 PE=1 SV=2 6.2 3880.9 - 59976.6 - - - 0.9918 - 1.404 0.409 - 30.5 1 1 0 0.0018 16 0 0 0 - - - - - 2.905 1 221125_WJC_METTL3_EV_vs_WT_F05.24356.24356.3 1.58E-06 Dec-76 K.LSSSIIHEIDSILGNKPYSK.K "sp|Q13303|KCAB2_HUMAN,tr|A0A5F9UN28|A0A5F9UN28_HUMAN,tr|A0A590UJB6|A0A590UJB6_HUMAN" 3 2200.1739 2.12 73872 24356 3 2200.176694 734.3986 Voltage-gated potassium channel subunit beta-2 OS=Homo sapiens OX=9606 GN=KCNAB2 PE=1 SV=2 6.75 3881.9 - 18747.3 - - - 1.2476 - 2.697 0.517 - 114.8 1 2 0 0.0027 20 0 0 0 2.90E+06 1.37E+06 - - - 6.7102 0.9998 221125_WJC_METTL3_EV_vs_WT_F05.24372.24372.3 0.000187 Jun-84 K.K[136.11]PPEADMNIFEDIGDYVPSTTK[136.11].T sp|Q13123|RED_HUMAN 1 2482.1909 1.05 73879 24372 3 2482.197627 828.4042 Protein Red OS=Homo sapiens OX=9606 GN=IK PE=1 SV=3 4.11 3884.3 - 35989 - - - 2.7274 - 1.522 0.537 - 27.8 1 2 0 0.0068 22 0 0 0 7.28E+06 6.93E+06 - - - 5.521 0.9999 221125_WJC_METTL3_EV_vs_WT_F05.24373.24373.3 1.63E-05 Jun-84 K.KPPEADMNIFEDIGDYVPSTTK.T sp|Q13123|RED_HUMAN 1 2466.1625 1.05 73880 24373 3 2466.164868 823.0614 Protein Red OS=Homo sapiens OX=9606 GN=IK PE=1 SV=3 4.11 3884.5 - 47376.6 - - - 0.9776 - 1.384 0.559 - 26.5 1 2 0 0.0024 22 0 0 0 7.28E+06 6.93E+06 - - - 5.5421 0.9998 221125_WJC_METTL3_EV_vs_WT_F05.24378.24378.3 4.56E-06 Sep-92 K.TSTSNVEQYQAMVTSLEESLNKEK.Q sp|P12270|TPR_HUMAN 1 2715.2909 3.92 73883 24378 3 2715.293632 906.1042 Nucleoprotein TPR OS=Homo sapiens OX=9606 GN=TPR PE=1 SV=3 4.49 3885.2 - 53163.1 - - - 1.0039 - 2.015 0.566 - 46.3 1 2 1 0.0027 24 0 0 0 1.36E+06 3.48E+05 - - - 6.4768 0.9449 221125_WJC_METTL3_EV_vs_WT_F05.24384.24384.3 0.039 Apr-96 K.DGDVTVTNDGATILSMMDVDHQIAK[136.11].L "sp|P48643|TCPE_HUMAN,tr|E9PCA1|E9PCA1_HUMAN,tr|B7ZAR1|B7ZAR1_HUMAN" 3 2653.2455 0.25 73887 24384 3 2654.246361 885.4224 T-complex protein 1 subunit epsilon OS=Homo sapiens OX=9606 GN=CCT5 PE=1 SV=1 3.97 3886.1 - 42303.3 - - - 377.2282 - 0.957 0.417 - 10.9 1 2 0 1.0009 25 0 0 0 1.63E+05 6.43E+05 - - - 2.8108 0.9883 221125_WJC_METTL3_EV_vs_WT_F05.24397.24397.3 0.0493 May-88 R.IITITGTQDQIQNAQYLLQNSVK[136.11].Q sp|P61978|HNRPK_HUMAN 1 2596.3952 1.59 73895 24397 3 2596.393017 866.4723 Heterogeneous nuclear ribonucleoprotein K OS=Homo sapiens OX=9606 GN=HNRNPK PE=1 SV=1 5.83 3887.9 - 48580.8 - - - -0.8338 - 1.282 0.232 - 15.2 1 2 0 -0.0022 23 0 0 0 6.93E+05 4.36E+05 - - - 1.7088 0.9948 221125_WJC_METTL3_EV_vs_WT_F05.24407.24407.3 0.0269 5/112 K.MK[136.11]ETAENYLGHTAK[136.11]NAVITVPAYFNDSQR[166.11].Q "sp|P38646|GRP75_HUMAN,tr|H0Y8K0|H0Y8K0_HUMAN,tr|A0A7I2V2S7|A0A7I2V2S7_HUMAN,tr|A0A7I2V2G2|A0A7I2V2G2_HUMAN,tr|A0A7I2V3F7|A0A7I2V3F7_HUMAN,tr|A0A7I2YQB2|A0A7I2YQB2_HUMAN,tr|D6RCD7|D6RCD7_HUMAN" 7 3293.6349 0.01 73901 24407 3 3293.641075 1098.8856 "Stress-70 protein, mitochondrial OS=Homo sapiens OX=9606 GN=HSPA9 PE=1 SV=2" 6.51 3889.3 - 66550.5 - - - 1.8654 - 1.334 0.398 - 13.2 1 2 2 0.0061 29 0 0 0 4.56E+04 5.51E+06 - - - 3.6386 1 221125_WJC_METTL3_EV_vs_WT_F05.24419.24419.3 5.44E-08 Nov-60 K.K[136.11]VSQEILELLNTTTAK[136.11].E "sp|Q86U44|MTA70_HUMAN,tr|H0YFV6|H0YFV6_HUMAN" 2 1803.0324 0 73908 24419 3 1803.034118 602.0181 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 6.14 3891 - 117559 - - - 0.9362 - 2.7 0.631 - 195.4 1 2 0 0.0017 16 0 0 0 5.10E+04 1.51E+07 - - - 8.1231 0.9818 221125_WJC_METTL3_EV_vs_WT_F05.24426.24426.2 0.00134 24-Jul K.K[136.11]VSQEILELLNTT.T "sp|Q86U44|MTA70_HUMAN,tr|H0YFV6|H0YFV6_HUMAN" 2 1494.8385 0.001 73913 24426 2 1494.838909 748.4265 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 4.53 3892 - 70844.3 - - - 0.291 - 1.747 0.421 - 179.6 1 1 0 0.0004 13 0 0 0 0.00E+00 5.60E+06 - - - 3.5822 0.9941 221125_WJC_METTL3_EV_vs_WT_F05.24463.24463.3 2.49E-06 Dec-76 Y.YNTIDDLKDQIVDLTVGNNK.T sp|P35527|K1C9_HUMAN 1 2277.1489 642.37 73934 24463 3 2277.150731 760.0569 "Keratin, type I cytoskeletal 9 OS=Homo sapiens OX=9606 GN=KRT9 PE=1 SV=3" 4.14 3897.3 - 438182 - - - 0.8234 - 2.741 0.621 - 173.1 1 1 1 0.0019 20 0 0 0 1.82E+08 2.83E+05 - - - 7.9092 1 221125_WJC_METTL3_EV_vs_WT_F05.24468.24468.4 1.57E-06 Nov-96 R.THNLEPYFESFINNLRR.R sp|P04264|K2C1_HUMAN 1 2149.0705 770.67 73937 24468 4 2149.072129 538.2749 "Keratin, type II cytoskeletal 1 OS=Homo sapiens OX=9606 GN=KRT1 PE=1 SV=6" 6.42 3897.9 - 103274 - - - 0.7641 - 2.421 0.517 - 123.9 1 2 0 0.0016 17 0 0 0 3.85E+07 5.00E+04 - - - 4.0325 1 221125_WJC_METTL3_EV_vs_WT_F05.24471.24471.3 4.27E-08 Nov-84 K.EKPYFPIPEEYTFIQNVPLEDR.V "sp|Q00839|HNRPU_HUMAN,tr|A0A1W2PQL0|A0A1W2PQL0_HUMAN,tr|A0A1W2PPL4|A0A1W2PPL4_HUMAN,tr|A0A1W2PQ74|A0A1W2PQ74_HUMAN,tr|Q5RI18|Q5RI18_HUMAN,tr|A0A1W2PP35|A0A1W2PP35_HUMAN,tr|A0A1W2PPS1|A0A1W2PPS1_HUMAN,tr|A0A1W2PRZ7|A0A1W2PRZ7_HUMAN,tr|A0A1W2PPH7|A0A1W2PPH7_HUMAN,tr|A0A1W2PP34|A0A1W2PP34_HUMAN,tr|A0A1X7SBS1|A0A1X7SBS1_HUMAN" 11 2723.3483 1.19 73938 24471 3 2723.347291 908.79 Heterogeneous nuclear ribonucleoprotein U OS=Homo sapiens OX=9606 GN=HNRNPU PE=1 SV=6 4.25 3898.3 - 103523 - - - -0.3646 - 2.361 0.624 - 81.6 1 2 0 -0.001 22 0 0 0 1.39E+07 1.17E+07 - - - 7.5335 1 221125_WJC_METTL3_EV_vs_WT_F05.24472.24472.4 1.63E-05 7/120 K.NPDDPDMVDVFMDHLDIDHNK.K sp|P20930|FILA_HUMAN 1 2481.0577 329.03 73939 24472 4 2481.05638 621.2717 Filaggrin OS=Homo sapiens OX=9606 GN=FLG PE=1 SV=3 3.99 3898.5 - 77540.1 - - - -0.522 - 1.634 0.63 - 27.5 1 2 0 -0.0013 21 0 0 0 9.35E+06 2.84E+04 - - - 4.8715 0.9999 221125_WJC_METTL3_EV_vs_WT_F05.24477.24477.3 3.88E-05 Nov-84 K.EK[136.11]PYFPIPEEYTFIQNVPLEDR[166.11].V "sp|Q00839|HNRPU_HUMAN,tr|A0A1W2PQL0|A0A1W2PQL0_HUMAN,tr|A0A1W2PPL4|A0A1W2PPL4_HUMAN,tr|A0A1W2PQ74|A0A1W2PQ74_HUMAN,tr|Q5RI18|Q5RI18_HUMAN,tr|A0A1W2PP35|A0A1W2PP35_HUMAN,tr|A0A1W2PPS1|A0A1W2PPS1_HUMAN,tr|A0A1W2PRZ7|A0A1W2PRZ7_HUMAN,tr|A0A1W2PPH7|A0A1W2PPH7_HUMAN,tr|A0A1W2PP34|A0A1W2PP34_HUMAN,tr|A0A1X7SBS1|A0A1X7SBS1_HUMAN" 11 2741.3708 1.19 73941 24477 3 2741.374198 914.7975 Heterogeneous nuclear ribonucleoprotein U OS=Homo sapiens OX=9606 GN=HNRNPU PE=1 SV=6 4.25 3899.3 - 265449 - - - 1.2563 - 2.253 0.471 - 68 1 2 0 0.0034 22 0 0 0 1.38E+07 1.16E+07 - - - 5.716 0.9664 221125_WJC_METTL3_EV_vs_WT_F05.24478.24478.4 0.00411 6/114 Y.YNTIDDLKDQIVDLTVGNNK.T sp|P35527|K1C9_HUMAN 1 2277.1489 5.85 73942 24478 4 2277.150319 570.2945 "Keratin, type I cytoskeletal 9 OS=Homo sapiens OX=9606 GN=KRT9 PE=1 SV=3" 4.14 3899.4 - 270456 - - - 0.6425 - 1.38 0.466 - 28.3 1 1 1 0.0015 20 0 0 0 9.07E+06 1.55E+06 - - - 3.3893 0.9993 221125_WJC_METTL3_EV_vs_WT_F05.24479.24479.4 0.0115 5/168 K.MK[136.11]ETAENYLGHTAK[136.11]NAVITVPAYFNDSQR[166.11].Q "sp|P38646|GRP75_HUMAN,tr|H0Y8K0|H0Y8K0_HUMAN,tr|A0A7I2V2S7|A0A7I2V2S7_HUMAN,tr|A0A7I2V2G2|A0A7I2V2G2_HUMAN,tr|A0A7I2V3F7|A0A7I2V3F7_HUMAN,tr|A0A7I2YQB2|A0A7I2YQB2_HUMAN,tr|D6RCD7|D6RCD7_HUMAN" 7 3293.6349 0.05 73943 24479 4 3293.635759 824.416 "Stress-70 protein, mitochondrial OS=Homo sapiens OX=9606 GN=HSPA9 PE=1 SV=2" 6.51 3899.5 - 86726.4 - - - 0.2514 - 1.202 0.409 - 8.6 1 2 2 0.0008 29 0 0 0 7.03E+04 1.51E+06 - - - 2.8424 1 221125_WJC_METTL3_EV_vs_WT_F05.24492.24492.3 5.83E-06 Sep-80 K.NPDDPDMVDVFMDHLDIDHNK.K sp|P20930|FILA_HUMAN 1 2481.0577 99.73 73950 24492 3 2481.060405 828.0265 Filaggrin OS=Homo sapiens OX=9606 GN=FLG PE=1 SV=3 3.99 3901.3 - 151947 - - - 1.1003 - 1.775 0.625 - 50.3 1 2 0 0.0027 21 0 0 0 1.65E+06 1.65E+04 - - - 6.883 0.9999 221125_WJC_METTL3_EV_vs_WT_F05.24523.24523.3 8.41E-05 7/100 R.SSGTASSVAFTPLQGLEIVNPQAAEK.K "sp|Q8WWY3|PRP31_HUMAN,tr|E7EVX8|E7EVX8_HUMAN" 2 2601.3286 1.28 73967 24523 3 2601.327059 868.1168 U4\U6 small nuclear ribonucleoprotein Prp31 OS=Homo sapiens OX=9606 GN=PRPF31 PE=1 SV=2 4.53 3905.5 - 77717 - - - -0.597 - 1.7 0.533 - 41.7 1 2 0 -0.0016 26 0 0 0 1.96E+07 1.53E+07 - - - 5.7028 0.9901 221125_WJC_METTL3_EV_vs_WT_F05.24554.24554.3 0.0451 Mar-88 R.SAAASNLSGLSLQEAQQILNVSK.L "sp|Q9Y3D7|TIM16_HUMAN,tr|I3L3T0|I3L3T0_HUMAN,tr|A0A0A6YYL4|A0A0A6YYL4_HUMAN,tr|I3L1U7|I3L1U7_HUMAN,tr|I3L0X9|I3L0X9_HUMAN" 5 2328.2285 1.73 73983 24554 3 2328.228716 777.0834 Mitochondrial import inner membrane translocase subunit TIM16 OS=Homo sapiens OX=9606 GN=PAM16 PE=1 SV=2 5.72 3909.9 - 36963 - - - 0.0911 - 0.947 0.305 - 8.4 1 2 0 0.0002 23 0 0 0 4.81E+05 2.78E+05 - - - 1.8126 0.9997 221125_WJC_METTL3_EV_vs_WT_F05.24563.24563.2 0.000135 Apr-36 R.YVASYLLAALGGNSSPSAK[136.11].D sp|P05387|RLA2_HUMAN 1 1875.9822 1.02 73990 24563 2 1875.980923 938.9984 60S acidic ribosomal protein P2 OS=Homo sapiens OX=9606 GN=RPLP2 PE=1 SV=1 8.5 3911.2 - 39095.3 - - - -0.6695 - 1.287 0.527 - 29.1 1 2 0 -0.0013 19 0 0 0 9.35E+05 9.15E+05 - - - 3.5534 0.9993 221125_WJC_METTL3_EV_vs_WT_F05.24576.24576.2 9.87E-07 Jul-36 R.YVASYLLAALGGNSSPSAK.D sp|P05387|RLA2_HUMAN 1 1867.968 1.02 73999 24576 2 1867.973759 934.9913 60S acidic ribosomal protein P2 OS=Homo sapiens OX=9606 GN=RPLP2 PE=1 SV=1 8.5 3913 - 63257 - - - 3.0943 - 1.791 0.558 - 119.2 1 2 0 0.0058 19 0 0 0 9.35E+05 9.15E+05 - - - 4.5934 0.9999 221125_WJC_METTL3_EV_vs_WT_F05.24577.24577.3 6.14E-05 9/112 R.R[166.11]AEQDSTTVAAFASSLVSGLNSSASEPAK[136.11].E "sp|Q86U44|MTA70_HUMAN,tr|F5H6D8|F5H6D8_HUMAN,tr|H0YFV6|H0YFV6_HUMAN,tr|B4DTN4|B4DTN4_HUMAN" 4 2898.4326 0.001 74000 24577 3 2898.437117 967.1515 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 4.68 3913.1 - 58017.5 - - - 1.5653 - 2.141 0.491 - 68.3 1 2 0 0.0045 29 0 0 0 0.00E+00 6.84E+05 - - - 5.7643 0.9678 221125_WJC_METTL3_EV_vs_WT_F05.24590.24590.4 7.72E-05 9/126 M.NVGTRPINLEPIFQGYIDSLKR.Y sp|P35908|K22E_HUMAN 1 2529.3704 79.13 74009 24590 4 2529.375467 633.3499 "Keratin, type II cytoskeletal 2 epidermal OS=Homo sapiens OX=9606 GN=KRT2 PE=1 SV=2" 8.59 3914.8 - 107347 - - - 2.0203 - 1.845 0.397 - 38.2 1 1 0 0.0051 22 0 0 0 1.49E+06 1.88E+04 - - - 2.8805 0.9948 221125_WJC_METTL3_EV_vs_WT_F05.24595.24595.3 0.109 Apr-80 K.WSTDEVSEFIQSLPGC[160.03]EEHGK[136.11].V sp|Q96JM7|LMBL3_HUMAN 1 2442.0889 1.47 74012 24595 3 2442.081611 815.0369 Lethal(3)malignant brain tumor-like protein 3 OS=Homo sapiens OX=9606 GN=L3MBTL3 PE=1 SV=2 4.25 3915.5 - 55830.3 - - - -2.9868 - 1.146 0.377 - 11.4 1 2 0 -0.0073 21 0 0 0 4.43E+05 3.01E+05 - - - 3.0679 0.9992 221125_WJC_METTL3_EV_vs_WT_F05.24610.24610.3 0.00107 Jul-88 K.QKVEGTEPTTAFNLFVGNLNFNK.S "sp|P19338|NUCL_HUMAN,tr|A0A7I2V506|A0A7I2V506_HUMAN,tr|A0A7I2V699|A0A7I2V699_HUMAN,tr|A0A7I2V2U7|A0A7I2V2U7_HUMAN,tr|A0A7I2V3F3|A0A7I2V3F3_HUMAN,tr|A0A7I2V428|A0A7I2V428_HUMAN,tr|A0A7I2V349|A0A7I2V349_HUMAN,tr|H7BY16|H7BY16_HUMAN,tr|A0A7I2V5M5|A0A7I2V5M5_HUMAN,tr|A0A7I2V2S8|A0A7I2V2S8_HUMAN,tr|C9JLB1|C9JLB1_HUMAN" 11 2567.302 1.05 74023 24610 3 2567.30415 856.7746 Nucleolin OS=Homo sapiens OX=9606 GN=NCL PE=1 SV=3 6.14 3917.6 - 70566 - - - 0.8363 - 1.473 0.47 - 43 1 2 1 0.0021 23 0 0 0 1.20E+07 1.14E+07 - - - 4.688 0.9998 221125_WJC_METTL3_EV_vs_WT_F05.24615.24615.3 2.85E-05 Sep-88 K.QK[136.11]VEGTEPTTAFNLFVGNLNFNK[136.11].S "sp|P19338|NUCL_HUMAN,tr|A0A7I2V506|A0A7I2V506_HUMAN,tr|A0A7I2V699|A0A7I2V699_HUMAN,tr|A0A7I2V2U7|A0A7I2V2U7_HUMAN,tr|A0A7I2V3F3|A0A7I2V3F3_HUMAN,tr|A0A7I2V428|A0A7I2V428_HUMAN,tr|A0A7I2V349|A0A7I2V349_HUMAN,tr|H7BY16|H7BY16_HUMAN,tr|A0A7I2V5M5|A0A7I2V5M5_HUMAN,tr|A0A7I2V2S8|A0A7I2V2S8_HUMAN,tr|C9JLB1|C9JLB1_HUMAN" 11 2583.3304 1.05 74025 24615 3 2583.327799 862.1174 Nucleolin OS=Homo sapiens OX=9606 GN=NCL PE=1 SV=3 6.14 3918.2 - 137658 - - - -1.008 - 2.316 0.497 - 70.3 1 2 1 -0.0026 23 0 0 0 1.20E+07 1.14E+07 - - - 6.0506 0.9719 221125_WJC_METTL3_EV_vs_WT_F05.24619.24619.3 0.00623 Apr-48 R.KIEEIKDFLLTAR.R "sp|P63173|RL38_HUMAN,tr|J3KT73|J3KT73_HUMAN,tr|J3QL01|J3QL01_HUMAN,tr|J3KSP2|J3KSP2_HUMAN" 4 1574.9032 1.06 74028 24619 3 1574.905553 525.975 60S ribosomal protein L38 OS=Homo sapiens OX=9606 GN=RPL38 PE=1 SV=2 6.18 3918.7 - 35729 - - - 1.4979 - 1.06 0.325 - 22.3 1 2 1 0.0024 13 0 0 0 1.20E+06 1.13E+06 - - - 2.3208 0.9978 221125_WJC_METTL3_EV_vs_WT_F05.24634.24634.3 0.00307 6/112 K.MK[136.11]ETAENYLGHTAK[136.11]NAVITVPAYFNDSQR[166.11].Q "sp|P38646|GRP75_HUMAN,tr|H0Y8K0|H0Y8K0_HUMAN,tr|A0A7I2V2S7|A0A7I2V2S7_HUMAN,tr|A0A7I2V2G2|A0A7I2V2G2_HUMAN,tr|A0A7I2V3F7|A0A7I2V3F7_HUMAN,tr|A0A7I2YQB2|A0A7I2YQB2_HUMAN,tr|D6RCD7|D6RCD7_HUMAN" 7 3293.6349 0.01 74039 24634 3 3293.640959 1098.8856 "Stress-70 protein, mitochondrial OS=Homo sapiens OX=9606 GN=HSPA9 PE=1 SV=2" 6.51 3920.8 - 68429.9 - - - 1.8302 - 1.602 0.42 - 14.1 1 2 2 0.006 29 0 0 0 3.00E+04 4.23E+06 - - - 4.3051 1 221125_WJC_METTL3_EV_vs_WT_F05.24638.24638.3 0.0188 14/60 K.K[136.11]VSQEILELLNTTTAK[136.11].E "sp|Q86U44|MTA70_HUMAN,tr|H0YFV6|H0YFV6_HUMAN" 2 1803.0324 0 74041 24638 3 1803.031149 602.0181 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 6.14 3921.4 - 268945 - - - -0.7105 - 3.273 0.617 - 365.1 1 2 0 -0.0013 16 0 0 0 3.39E+04 1.31E+07 - - - 8.4609 1 221125_WJC_METTL3_EV_vs_WT_F05.24661.24661.3 7.76E-05 Sep-72 R.QNLDTIVQAIQHIEGTQEK.Q sp|Q01664|TFAP4_HUMAN 1 2164.1124 2.04 74054 24661 3 2164.113386 722.3781 Transcription factor AP-4 OS=Homo sapiens OX=9606 GN=TFAP4 PE=1 SV=2 4.65 3924.5 - 105606 - - - 0.4505 - 2.439 0.475 - 97.3 1 2 0 0.001 19 0 0 0 5.13E+06 2.52E+06 - - - 6.026 0.98 221125_WJC_METTL3_EV_vs_WT_F05.24680.24680.3 1.01E-06 8/124 R.AEQDSTTVAAFASSLVSGLNSSASEPAK[136.11]EPAK[136.11].K "sp|Q86U44|MTA70_HUMAN,tr|F5H6D8|F5H6D8_HUMAN,tr|H0YFV6|H0YFV6_HUMAN,tr|B4DTN4|B4DTN4_HUMAN" 4 3165.5648 0.001 74065 24680 3 3166.560384 1056.1956 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 4.41 3927.1 - 109693 - - - 314.4943 - 1.881 0.536 - 43.2 1 2 1 0.9956 32 0 0 0 0.00E+00 2.91E+06 - - - 5.6937 0.9993 221125_WJC_METTL3_EV_vs_WT_F05.24697.24697.2 0.00396 22-Jul K.VDLLNQEIEFLK.V sp|P35908|K22E_HUMAN 1 1459.7922 999 74073 24697 2 1459.794098 730.9034 "Keratin, type II cytoskeletal 2 epidermal OS=Homo sapiens OX=9606 GN=KRT2 PE=1 SV=2" 4.14 3929.5 - 354049 - - - 1.2687 - 1.429 0.423 - 104.4 1 2 0 0.0019 12 0 0 0 1.51E+06 0.00E+00 - - - 3.104 0.9999 221125_WJC_METTL3_EV_vs_WT_F05.24699.24699.3 9.18E-10 15/96 K.SEDSTK[136.11]DDIDLDALAAEIEGAGAAK[136.11].E "sp|O60841|IF2P_HUMAN,tr|A0A087WUT6|A0A087WUT6_HUMAN" 2 2520.205 0.72 74075 24699 3 2520.198544 841.0756 Eukaryotic translation initiation factor 5B OS=Homo sapiens OX=9606 GN=EIF5B PE=1 SV=4 3.8 3929.8 - 126895 - - - -2.5565 - 3.282 0.625 - 279.5 1 2 1 -0.0064 25 0 0 0 1.22E+06 1.69E+06 - - - 8.2405 0.9986 221125_WJC_METTL3_EV_vs_WT_F05.24731.24731.3 0.0023 Jun-84 K.EKPYFPIPEEYTFIQNVPLEDR.V "sp|Q00839|HNRPU_HUMAN,tr|A0A1W2PQL0|A0A1W2PQL0_HUMAN,tr|A0A1W2PPL4|A0A1W2PPL4_HUMAN,tr|A0A1W2PQ74|A0A1W2PQ74_HUMAN,tr|Q5RI18|Q5RI18_HUMAN,tr|A0A1W2PP35|A0A1W2PP35_HUMAN,tr|A0A1W2PPS1|A0A1W2PPS1_HUMAN,tr|A0A1W2PRZ7|A0A1W2PRZ7_HUMAN,tr|A0A1W2PPH7|A0A1W2PPH7_HUMAN,tr|A0A1W2PP34|A0A1W2PP34_HUMAN,tr|A0A1X7SBS1|A0A1X7SBS1_HUMAN" 11 2723.3483 1.26 74093 24731 3 2723.353238 908.79 Heterogeneous nuclear ribonucleoprotein U OS=Homo sapiens OX=9606 GN=HNRNPU PE=1 SV=6 4.25 3934.2 - 40894.1 - - - 1.8191 - 1.485 0.358 - 35.6 1 2 0 0.005 22 0 0 0 1.61E+06 1.28E+06 - - - 3.4674 1 221125_WJC_METTL3_EV_vs_WT_F05.24745.24745.3 2.88E-08 Oct-80 K.WGDAGAEYVVESTGVFTTMEK.A "sp|P04406|G3P_HUMAN,tr|E7EUT5|E7EUT5_HUMAN" 2 2276.0307 0.04 74101 24745 3 2276.029159 759.6842 Glyceraldehyde-3-phosphate dehydrogenase OS=Homo sapiens OX=9606 GN=GAPDH PE=1 SV=3 4 3936.1 - 89473.3 - - - -0.6836 - 2.228 0.657 - 126.6 1 2 0 -0.0016 21 0 0 0 3.71E+06 8.32E+07 - - - 7.7851 0.9761 221125_WJC_METTL3_EV_vs_WT_F05.24755.24755.4 0.00545 9/180 K.GIEILTDMSR[166.11]PVELSDR[166.11]ETLLNSATTSLNSK[136.11].V sp|P50991|TCPD_HUMAN 1 3417.7656 0.19 74108 24755 4 3417.749231 855.4487 T-complex protein 1 subunit delta OS=Homo sapiens OX=9606 GN=CCT4 PE=1 SV=4 4.51 3937.4 - 106949 - - - -4.7762 - 1.546 0.34 - 40.6 1 2 1 -0.0163 31 0 0 0 4.14E+06 2.20E+07 - - - 2.3132 0.9909 221125_WJC_METTL3_EV_vs_WT_F05.24766.24766.4 6.66E-10 13/162 R.PHNVQPNWITLGNQLDGIHLLDPDVVAR[166.11].F sp|Q86U44|MTA70_HUMAN 1 3140.6395 0.01 74112 24766 4 3140.627993 786.1671 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 5.14 3939 - 154536 - - - -3.6594 - 3.065 0.593 - 63.4 1 1 0 -0.0115 28 0 0 0 3.73E+04 3.91E+06 - - - 4.732 1 221125_WJC_METTL3_EV_vs_WT_F05.24795.24795.3 1.29E-07 16/76 K.HAASDVDLEIESLLNQQSTK[136.11].E "sp|Q86U44|MTA70_HUMAN,tr|F5H6D8|F5H6D8_HUMAN,tr|H0YFV6|H0YFV6_HUMAN,tr|B4DTN4|B4DTN4_HUMAN" 4 2205.1005 0.27 74125 24795 3 2205.09775 736.0408 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 4.31 3942.9 - 178483 - - - -1.2272 - 3.296 0.617 - 298.1 1 2 0 -0.0027 20 0 0 0 2.25E+06 8.44E+06 - - - 8.3117 0.9999 221125_WJC_METTL3_EV_vs_WT_F05.24804.24804.4 1.08E-05 17/162 R.LKPGFEVKPSELEPLHGVPGPGLDPFPR.H sp|P54259|ATN1_HUMAN 1 3008.6124 21.11 74131 24804 4 3008.607072 753.1604 Atrophin-1 OS=Homo sapiens OX=9606 GN=ATN1 PE=1 SV=3 5.53 3944 - 440447 - - - -1.7639 - 2.581 0.466 - 72.5 1 2 0 -0.0053 28 0 0 0 2.30E+06 1.09E+05 - - - 3.575 1 221125_WJC_METTL3_EV_vs_WT_F05.24813.24813.4 1.67E-13 26/114 R.PLFPHVLC[160.03]HNC[160.03]AVEFNFGQK.E "sp|Q00839|HNRPU_HUMAN,tr|A0A1W2PQL0|A0A1W2PQL0_HUMAN,tr|A0A1W2PPL4|A0A1W2PPL4_HUMAN,tr|A0A1W2PQ74|A0A1W2PQ74_HUMAN,tr|Q5RI18|Q5RI18_HUMAN,tr|A0A1W2PP35|A0A1W2PP35_HUMAN,tr|A0A1W2PPS1|A0A1W2PPS1_HUMAN,tr|A0A1W2PRZ7|A0A1W2PRZ7_HUMAN,tr|A0A1W2PPH7|A0A1W2PPH7_HUMAN,tr|A0A1W2PP34|A0A1W2PP34_HUMAN,tr|A0A1X7SBS1|A0A1X7SBS1_HUMAN" 11 2413.146 1.57 74136 24813 4 2413.136457 604.2938 Heterogeneous nuclear ribonucleoprotein U OS=Homo sapiens OX=9606 GN=HNRNPU PE=1 SV=6 7.24 3945 - 867559 - - - -3.9451 - 4.493 0.655 - 572.3 1 1 0 -0.0095 20 0 0 0 4.19E+06 2.67E+06 - - - 5.4268 1 221125_WJC_METTL3_EV_vs_WT_F05.24814.24814.4 3.56E-11 23/114 R.PLFPHVLC[160.03]HNC[160.03]AVEFNFGQK[136.11].E "sp|Q00839|HNRPU_HUMAN,tr|A0A1W2PQL0|A0A1W2PQL0_HUMAN,tr|A0A1W2PPL4|A0A1W2PPL4_HUMAN,tr|A0A1W2PQ74|A0A1W2PQ74_HUMAN,tr|Q5RI18|Q5RI18_HUMAN,tr|A0A1W2PP35|A0A1W2PP35_HUMAN,tr|A0A1W2PPS1|A0A1W2PPS1_HUMAN,tr|A0A1W2PRZ7|A0A1W2PRZ7_HUMAN,tr|A0A1W2PPH7|A0A1W2PPH7_HUMAN,tr|A0A1W2PP34|A0A1W2PP34_HUMAN,tr|A0A1X7SBS1|A0A1X7SBS1_HUMAN" 11 2421.1602 1.57 74137 24814 4 2421.148578 606.2973 Heterogeneous nuclear ribonucleoprotein U OS=Homo sapiens OX=9606 GN=HNRNPU PE=1 SV=6 7.24 3945.1 - 466111 - - - -4.7907 - 3.825 0.636 - 464.8 1 1 0 -0.0116 20 0 0 0 4.19E+06 2.67E+06 - - - 5.207 1 221125_WJC_METTL3_EV_vs_WT_F05.24830.24830.4 2.87E-06 30/162 R.TVSLGAGAKDELHIVEAEAMNYEGSPIK.V "sp|P06748|NPM_HUMAN,tr|A0A7I2V4G8|A0A7I2V4G8_HUMAN,tr|A0A7I2YQC0|A0A7I2YQC0_HUMAN,tr|A0A7I2V433|A0A7I2V433_HUMAN,tr|A0A7I2V579|A0A7I2V579_HUMAN,tr|A0A7I2V2X9|A0A7I2V2X9_HUMAN,tr|A0A7I2V3G5|A0A7I2V3G5_HUMAN,tr|A0A7I2V5S2|A0A7I2V5S2_HUMAN,tr|A0A7I2V3U2|A0A7I2V3U2_HUMAN" 9 2928.4539 1.05 74149 24830 4 2928.442591 733.1207 Nucleophosmin OS=Homo sapiens OX=9606 GN=NPM1 PE=1 SV=2 4.57 3947.1 - 1.54E+06 - - - -3.858 - 5.24 0.615 - 750.6 1 2 1 -0.0113 28 0 0 0 1.91E+07 1.82E+07 - - - 5.0901 0.9999 221125_WJC_METTL3_EV_vs_WT_F05.24831.24831.4 1.06E-07 17/108 R.FAHIDGDHLTLLNVYHAFK[136.11].Q sp|O43143|DHX15_HUMAN 1 2218.1415 0.78 74150 24831 4 2218.132946 555.5426 Pre-mRNA-splicing factor ATP-dependent RNA helicase DHX15 OS=Homo sapiens OX=9606 GN=DHX15 PE=1 SV=2 6.26 3947.2 - 826193 - - - -3.8442 - 3.647 0.592 - 296.4 1 2 0 -0.0085 19 0 0 0 1.50E+06 1.92E+06 - - - 4.8141 0.9308 221125_WJC_METTL3_EV_vs_WT_F05.24835.24835.4 4.41E-05 18/102 R.K[136.11]IELFGR[166.11]PHNVQPNWITL.G sp|Q86U44|MTA70_HUMAN 1 2179.2021 0.02 74152 24835 4 2179.192787 545.8078 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 8.75 3947.8 - 4.32E+06 - - - -4.2795 - 2.984 0.429 - 159.3 1 1 0 -0.0093 18 0 0 0 1.22E+06 6.64E+07 - - - 3.3319 0.9576 221125_WJC_METTL3_EV_vs_WT_F05.24837.24837.3 6.38E-05 20/68 R.K[136.11]IELFGR[166.11]PHNVQPNWITL.G sp|Q86U44|MTA70_HUMAN 1 2179.2021 0 74154 24837 3 2179.191565 727.408 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 8.75 3948 - 2.92E+06 - - - -4.8403 - 2.895 0.48 - 447 1 1 0 -0.0105 18 0 0 0 9.65E+04 4.16E+07 - - - 6.5355 0.8272 221125_WJC_METTL3_EV_vs_WT_F05.24841.24841.3 6.29E-07 16/56 K.K[136.11]LLHHLSDLALTLPT.D "sp|Q86U44|MTA70_HUMAN,tr|B4E349|B4E349_HUMAN,tr|F5H6D8|F5H6D8_HUMAN,tr|H0YFV6|H0YFV6_HUMAN,tr|B4DTN4|B4DTN4_HUMAN" 5 1678.9861 0.001 74155 24841 3 1678.978007 560.6693 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 6.92 3948.5 - 911677 - - - -4.8452 - 2.886 0.322 - 211.2 1 1 0 -0.0081 15 0 0 0 0.00E+00 6.25E+06 - - - 4.8933 1 221125_WJC_METTL3_EV_vs_WT_F05.24844.24844.4 1.02E-11 33/234 R.GKPPPLLPSVLGPAGGDREALGLGPPAAQLTPPPAPVGLR.G "sp|Q8IY67|RAVR1_HUMAN,tr|E9PAU2|E9PAU2_HUMAN,tr|A0A087WZ13|A0A087WZ13_HUMAN" 3 3830.1571 1.08 74156 24844 4 3830.145072 958.5465 Ribonucleoprotein PTB-binding 1 OS=Homo sapiens OX=9606 GN=RAVER1 PE=1 SV=1 8.75 3948.9 - 1.89E+06 - - - -3.1309 - 3.99 0.646 - 213.1 1 2 1 -0.012 40 0 0 0 8.24E+06 7.63E+06 - - - 5.2449 0.9992 221125_WJC_METTL3_EV_vs_WT_F05.24845.24845.4 1.59E-10 28/234 R.GK[136.11]PPPLLPSVLGPAGGDR[166.11]EALGLGPPAAQLTPPPAPVGLR[166.11].G "sp|Q8IY67|RAVR1_HUMAN,tr|E9PAU2|E9PAU2_HUMAN,tr|A0A087WZ13|A0A087WZ13_HUMAN" 3 3858.1878 1.08 74157 24845 4 3858.167386 965.5542 Ribonucleoprotein PTB-binding 1 OS=Homo sapiens OX=9606 GN=RAVER1 PE=1 SV=1 8.75 3949.1 - 1.37E+06 - - - -5.2921 - 3.963 0.621 - 160.8 1 2 1 -0.0204 40 0 0 0 8.24E+06 7.63E+06 - - - 5.023 1 221125_WJC_METTL3_EV_vs_WT_F05.24846.24846.4 4.49E-10 26/150 R.SFGTEDRPTDRPIPPRDEVFEYIIFR.G "sp|Q8ND56|LS14A_HUMAN,tr|I3L4Q1|I3L4Q1_HUMAN,tr|A0A140TA76|A0A140TA76_HUMAN,tr|K7EMZ9|K7EMZ9_HUMAN" 4 3151.5727 1.05 74158 24846 4 3151.561701 788.9005 Protein LSM14 homolog A OS=Homo sapiens OX=9606 GN=LSM14A PE=1 SV=3 4.59 3949.1 - 4.64E+06 - - - -3.4897 - 3.167 0.679 - 102.9 1 2 1 -0.011 26 0 0 0 1.71E+08 1.63E+08 - - - 5.4966 0.9983 221125_WJC_METTL3_EV_vs_WT_F05.24851.24851.4 1.18E-05 19/150 K.SGFEPASLKEEVGEEAIVELVENGKK.V "sp|P35579|MYH9_HUMAN,tr|Q5BKV1|Q5BKV1_HUMAN,tr|B1AH99|B1AH99_HUMAN" 3 2787.4178 1.75 74160 24851 4 2787.40631 697.8617 Myosin-9 OS=Homo sapiens OX=9606 GN=MYH9 PE=1 SV=4 4.36 3949.8 - 905226 - - - -4.1296 - 3.222 0.448 - 224.5 1 2 1 -0.0115 26 0 0 0 8.48E+06 4.84E+06 - - - 3.4913 0.9997 221125_WJC_METTL3_EV_vs_WT_F05.24853.24853.4 1.09E-06 19/180 K.GIEILTDMSRPVELSDRETLLNSATTSLNSK.V sp|P50991|TCPD_HUMAN 1 3389.7348 0.19 74161 24853 4 3389.726425 848.441 T-complex protein 1 subunit delta OS=Homo sapiens OX=9606 GN=CCT4 PE=1 SV=4 4.51 3950 - 692077 - - - -2.4751 - 3.183 0.503 - 196.2 1 2 1 -0.0084 31 0 0 0 4.12E+06 2.16E+07 - - - 3.9537 0.9988 221125_WJC_METTL3_EV_vs_WT_F05.24854.24854.4 3.31E-06 16/120 K.KLEEVVQILGDKFPC[160.03]TLVAQK.L sp|Q9BY32|ITPA_HUMAN 1 2414.3243 1.08 74162 24854 4 2414.31817 604.5884 Inosine triphosphate pyrophosphatase OS=Homo sapiens OX=9606 GN=ITPA PE=1 SV=2 6.17 3950.2 - 291912 - - - -2.5469 - 2.968 0.395 - 184.4 1 2 1 -0.0061 21 0 0 0 1.49E+06 1.39E+06 - - - 3.0221 1 221125_WJC_METTL3_EV_vs_WT_F05.24858.24858.4 4.79E-10 28/96 K.HVINFDLPSDIEEYVHR.L "sp|O00571|DDX3X_HUMAN,sp|O15523|DDX3Y_HUMAN,tr|A0A2R8YFR4|A0A2R8YFR4_HUMAN,tr|A0A2R8YCW1|A0A2R8YCW1_HUMAN,tr|A0A2R8YDT5|A0A2R8YDT5_HUMAN,tr|A0A2R8Y645|A0A2R8Y645_HUMAN,tr|A0A2R8YF78|A0A2R8YF78_HUMAN,tr|A0A0D9SFB3|A0A0D9SFB3_HUMAN,tr|A0A2R8YFS5|A0A2R8YFS5_HUMAN,tr|A0A0D9SF53|A0A0D9SF53_HUMAN,tr|A0A087WVZ1|A0A087WVZ1_HUMAN,tr|A0A0J9YVQ7|A0A0J9YVQ7_HUMAN,tr|A0A2R8Y5G6|A0A2R8Y5G6_HUMAN,tr|A0A2R8Y7T2|A0A2R8Y7T2_HUMAN,tr|A0A0D9SG12|A0A0D9SG12_HUMAN,tr|F6S8Q4|F6S8Q4_HUMAN,tr|A0A2U3TZJ9|A0A2U3TZJ9_HUMAN,tr|A0A2R8Y4A4|A0A2R8Y4A4_HUMAN" 18 2082.0171 1.2 74164 24858 4 2082.008618 521.5115 ATP-dependent RNA helicase DDX3X OS=Homo sapiens OX=9606 GN=DDX3X PE=1 SV=3 4.72 3950.7 - 884426 - - - -4.0518 - 4.031 0.646 - 915.2 1 2 0 -0.0084 17 0 0 0 6.13E+06 5.12E+06 - - - 5.3304 1 221125_WJC_METTL3_EV_vs_WT_F05.24859.24859.3 1.54E-05 24/64 K.HVINFDLPSDIEEYVHR.L "sp|O00571|DDX3X_HUMAN,sp|O15523|DDX3Y_HUMAN,tr|A0A2R8YFR4|A0A2R8YFR4_HUMAN,tr|A0A2R8YCW1|A0A2R8YCW1_HUMAN,tr|A0A2R8YDT5|A0A2R8YDT5_HUMAN,tr|A0A2R8Y645|A0A2R8Y645_HUMAN,tr|A0A2R8YF78|A0A2R8YF78_HUMAN,tr|A0A0D9SFB3|A0A0D9SFB3_HUMAN,tr|A0A2R8YFS5|A0A2R8YFS5_HUMAN,tr|A0A0D9SF53|A0A0D9SF53_HUMAN,tr|A0A087WVZ1|A0A087WVZ1_HUMAN,tr|A0A0J9YVQ7|A0A0J9YVQ7_HUMAN,tr|A0A2R8Y5G6|A0A2R8Y5G6_HUMAN,tr|A0A2R8Y7T2|A0A2R8Y7T2_HUMAN,tr|A0A0D9SG12|A0A0D9SG12_HUMAN,tr|F6S8Q4|F6S8Q4_HUMAN,tr|A0A2U3TZJ9|A0A2U3TZJ9_HUMAN,tr|A0A2R8Y4A4|A0A2R8Y4A4_HUMAN" 18 2082.0171 1.6 74165 24859 3 2082.010144 695.013 ATP-dependent RNA helicase DDX3X OS=Homo sapiens OX=9606 GN=DDX3X PE=1 SV=3 4.72 3950.8 - 1.51E+06 - - - -3.3189 - 3.985 0.638 - 1087.5 1 2 0 -0.0069 17 0 0 0 1.03E+07 6.43E+06 - - - 9.1439 0.9991 221125_WJC_METTL3_EV_vs_WT_F05.24860.24860.4 0.000286 10/150 R.LVMGGPQQLYHLDAYIPLQINSHESK.A "sp|Q9NWS0|PIHD1_HUMAN,tr|M0QYA2|M0QYA2_HUMAN" 2 2950.5011 2.51 74166 24860 4 2950.49087 738.6326 PIH1 domain-containing protein 1 OS=Homo sapiens OX=9606 GN=PIH1D1 PE=1 SV=1 5.99 3950.9 - 1.22E+06 - - - -3.472 - 2.068 0.38 - 43.6 1 2 0 -0.0102 26 0 0 0 8.16E+06 3.25E+06 - - - 2.7599 1 221125_WJC_METTL3_EV_vs_WT_F05.24861.24861.4 1.13E-08 21/96 K.HVINFDLPSDIEEYVHR[166.11].L "sp|O00571|DDX3X_HUMAN,sp|O15523|DDX3Y_HUMAN,tr|A0A2R8YFR4|A0A2R8YFR4_HUMAN,tr|A0A2R8YCW1|A0A2R8YCW1_HUMAN,tr|A0A2R8YDT5|A0A2R8YDT5_HUMAN,tr|A0A2R8Y645|A0A2R8Y645_HUMAN,tr|A0A2R8YF78|A0A2R8YF78_HUMAN,tr|A0A0D9SFB3|A0A0D9SFB3_HUMAN,tr|A0A2R8YFS5|A0A2R8YFS5_HUMAN,tr|A0A0D9SF53|A0A0D9SF53_HUMAN,tr|A0A087WVZ1|A0A087WVZ1_HUMAN,tr|A0A0J9YVQ7|A0A0J9YVQ7_HUMAN,tr|A0A2R8Y5G6|A0A2R8Y5G6_HUMAN,tr|A0A2R8Y7T2|A0A2R8Y7T2_HUMAN,tr|A0A0D9SG12|A0A0D9SG12_HUMAN,tr|F6S8Q4|F6S8Q4_HUMAN,tr|A0A2U3TZJ9|A0A2U3TZJ9_HUMAN,tr|A0A2R8Y4A4|A0A2R8Y4A4_HUMAN" 18 2092.0253 1.2 74167 24861 4 2092.019245 524.0136 ATP-dependent RNA helicase DDX3X OS=Homo sapiens OX=9606 GN=DDX3X PE=1 SV=3 4.72 3951 - 1.10E+06 - - - -2.9058 - 3.779 0.601 - 513.4 1 2 0 -0.0061 17 0 0 0 6.13E+06 5.12E+06 - - - 4.917 1 221125_WJC_METTL3_EV_vs_WT_F05.24865.24865.4 5.96E-10 28/126 K.TSQLLETLNQLSTHTHVVDITR.T "sp|Q14203|DCTN1_HUMAN,tr|A0A804CDA6|A0A804CDA6_HUMAN,tr|E7EX90|E7EX90_HUMAN,tr|A0A7P0Z4C3|A0A7P0Z4C3_HUMAN,tr|E7EWF7|E7EWF7_HUMAN" 5 2505.3187 2.31 74169 24865 4 2505.311293 627.337 Dynactin subunit 1 OS=Homo sapiens OX=9606 GN=DCTN1 PE=1 SV=3 5.92 3951.5 - 9.04E+06 - - - -2.9629 - 5.489 0.625 - 917.6 1 2 0 -0.0074 22 0 0 0 4.44E+07 1.93E+07 - - - 5.2211 0.9999 221125_WJC_METTL3_EV_vs_WT_F05.24866.24866.3 6.78E-11 15/64 K.HVINFDLPSDIEEYVHR[166.11].L "sp|O00571|DDX3X_HUMAN,sp|O15523|DDX3Y_HUMAN,tr|A0A2R8YFR4|A0A2R8YFR4_HUMAN,tr|A0A2R8YCW1|A0A2R8YCW1_HUMAN,tr|A0A2R8YDT5|A0A2R8YDT5_HUMAN,tr|A0A2R8Y645|A0A2R8Y645_HUMAN,tr|A0A2R8YF78|A0A2R8YF78_HUMAN,tr|A0A0D9SFB3|A0A0D9SFB3_HUMAN,tr|A0A2R8YFS5|A0A2R8YFS5_HUMAN,tr|A0A0D9SF53|A0A0D9SF53_HUMAN,tr|A0A087WVZ1|A0A087WVZ1_HUMAN,tr|A0A0J9YVQ7|A0A0J9YVQ7_HUMAN,tr|A0A2R8Y5G6|A0A2R8Y5G6_HUMAN,tr|A0A2R8Y7T2|A0A2R8Y7T2_HUMAN,tr|A0A0D9SG12|A0A0D9SG12_HUMAN,tr|F6S8Q4|F6S8Q4_HUMAN,tr|A0A2U3TZJ9|A0A2U3TZJ9_HUMAN,tr|A0A2R8Y4A4|A0A2R8Y4A4_HUMAN" 18 2092.0253 1.6 74170 24866 3 2092.01714 698.3491 ATP-dependent RNA helicase DDX3X OS=Homo sapiens OX=9606 GN=DDX3X PE=1 SV=3 4.72 3951.6 - 1.82E+06 - - - -3.912 - 3.479 0.608 - 386.9 1 2 0 -0.0082 17 0 0 0 1.03E+07 6.43E+06 - - - 8.466 0.9819 221125_WJC_METTL3_EV_vs_WT_F05.24867.24867.4 4.24E-07 21/120 K.K[136.11]LLHHLSDLALTLPTDAVSIC[160.03].L "sp|Q86U44|MTA70_HUMAN,tr|B4E349|B4E349_HUMAN,tr|F5H6D8|F5H6D8_HUMAN,tr|H0YFV6|H0YFV6_HUMAN,tr|B4DTN4|B4DTN4_HUMAN" 5 2324.2654 0.02 74171 24867 4 2324.262249 582.0736 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 5.98 3951.7 - 828220 - - - -1.3359 - 3.177 0.384 - 194 1 1 0 -0.0031 21 0 0 0 1.01E+05 5.03E+06 - - - 2.9497 1 221125_WJC_METTL3_EV_vs_WT_F05.24872.24872.3 7.23E-10 21/60 K.K[136.11]VSQEILELLNTTTAK[136.11].E "sp|Q86U44|MTA70_HUMAN,tr|H0YFV6|H0YFV6_HUMAN" 2 1803.0324 0.01 74174 24872 3 1803.026639 602.0181 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 6.14 3952.3 - 2.45E+06 - - - -3.2118 - 4.166 0.684 - 820.1 1 2 0 -0.0058 16 0 0 0 8.01E+05 6.51E+07 - - - 9.8257 1 221125_WJC_METTL3_EV_vs_WT_F05.24881.24881.4 2.12E-09 20/114 K.TLSYLLPAIVHINHQPFLER.G "sp|P17844|DDX5_HUMAN,tr|A0A7I2V5F5|A0A7I2V5F5_HUMAN,tr|J3QRN5|J3QRN5_HUMAN,tr|A0A7I2V507|A0A7I2V507_HUMAN,tr|J3KTA4|J3KTA4_HUMAN,tr|A0A0G2JLI4|A0A0G2JLI4_HUMAN,tr|A0A7I2V2S0|A0A7I2V2S0_HUMAN,tr|J3QRQ7|J3QRQ7_HUMAN" 8 2360.3005 1.38 74181 24881 4 2360.297808 591.0824 Probable ATP-dependent RNA helicase DDX5 OS=Homo sapiens OX=9606 GN=DDX5 PE=1 SV=1 6.61 3953.5 - 528952 - - - -1.135 - 3.347 0.611 - 194.4 1 2 0 -0.0027 20 0 0 0 2.31E+06 1.68E+06 - - - 4.9473 0.8814 221125_WJC_METTL3_EV_vs_WT_F05.24882.24882.4 0.339 8/162 R.GPLPLSSQHR[166.11]GDADQASNILASFGLSAR[166.11].D "sp|P43243|MATR3_HUMAN,tr|A8MXP9|A8MXP9_HUMAN,tr|D6R991|D6R991_HUMAN,tr|A0A0R4J2E8|A0A0R4J2E8_HUMAN,tr|D6REM6|D6REM6_HUMAN" 5 2884.4695 1.29 74182 24882 4 2884.462408 722.1246 Matrin-3 OS=Homo sapiens OX=9606 GN=MATR3 PE=1 SV=2 6.75 3953.6 - 309124 - - - -2.4441 - 1.337 0.193 - 18.9 1 2 1 -0.007 28 0 0 0 4.42E+06 3.41E+06 - - - 0.9941 0.9997 221125_WJC_METTL3_EV_vs_WT_F05.24890.24890.4 8.45E-06 30/240 K.KPGILGDSPLGALQPGAQPANPLLGELPAGGGLPPELPPRR.G "sp|Q8IY67|RAVR1_HUMAN,tr|E9PAU2|E9PAU2_HUMAN,tr|A0A087WZ13|A0A087WZ13_HUMAN" 3 4017.2164 1.42 74188 24890 4 4017.195872 1005.3114 Ribonucleoprotein PTB-binding 1 OS=Homo sapiens OX=9606 GN=RAVER1 PE=1 SV=1 6.18 3954.6 - 1.20E+06 - - - -5.1025 - 3.154 0.555 - 195.8 1 2 0 -0.0205 41 0 0 0 7.48E+06 5.25E+06 - - - 4.381 1 221125_WJC_METTL3_EV_vs_WT_F05.24895.24895.4 4.58E-09 28/240 K.K[136.11]PGILGDSPLGALQPGAQPANPLLGELPAGGGLPPELPPR[166.11]R[166.11].G "sp|Q8IY67|RAVR1_HUMAN,tr|E9PAU2|E9PAU2_HUMAN,tr|A0A087WZ13|A0A087WZ13_HUMAN" 3 4045.2471 1.42 74191 24895 4 4045.230467 1012.3191 Ribonucleoprotein PTB-binding 1 OS=Homo sapiens OX=9606 GN=RAVER1 PE=1 SV=1 6.18 3955.4 - 1.25E+06 - - - -4.1142 - 4.081 0.644 - 172.4 1 2 0 -0.0166 41 0 0 0 7.48E+06 5.25E+06 - - - 5.2308 1 221125_WJC_METTL3_EV_vs_WT_F05.24896.24896.3 5.99E-10 22/64 T.RTHNLEPYFESFINNLR.R sp|P04264|K2C1_HUMAN 1 2149.0705 999 74192 24896 3 2149.061436 717.3641 "Keratin, type II cytoskeletal 1 OS=Homo sapiens OX=9606 GN=KRT1 PE=1 SV=6" 6.76 3955.5 - 394554 - - - -4.2116 - 4.154 0.636 - 912.5 1 1 0 -0.0091 17 0 0 0 7.54E+07 0.00E+00 - - - 9.2259 0.9936 221125_WJC_METTL3_EV_vs_WT_F05.24901.24901.4 6.02E-09 22/96 T.RTHNLEPYFESFINNLR.R sp|P04264|K2C1_HUMAN 1 2149.0705 1320.89 74195 24901 4 2149.063252 538.2749 "Keratin, type II cytoskeletal 1 OS=Homo sapiens OX=9606 GN=KRT1 PE=1 SV=6" 6.76 3956.2 - 2.03E+06 - - - -3.3666 - 3.067 0.611 - 515.4 1 1 0 -0.0072 17 0 0 0 1.12E+08 8.47E+04 - - - 4.9312 1 221125_WJC_METTL3_EV_vs_WT_F05.24902.24902.4 5.75E-13 25/108 K.GHYTEGAELVDSVLDVVR[166.11]K[136.11].E "sp|Q9BVA1|TBB2B_HUMAN,sp|P07437|TBB5_HUMAN,sp|Q13509|TBB3_HUMAN,sp|Q13885|TBB2A_HUMAN,sp|P68371|TBB4B_HUMAN,tr|A0A0B4J269|A0A0B4J269_HUMAN,tr|Q5ST81|Q5ST81_HUMAN,tr|Q5JP53|Q5JP53_HUMAN,tr|G3V2A3|G3V2A3_HUMAN" 9 2104.092 0.65 74196 24902 4 2104.08395 527.0303 Tubulin beta-2B chain OS=Homo sapiens OX=9606 GN=TUBB2B PE=1 SV=1 4.75 3956.3 - 672777 - - - -3.804 - 4.258 0.67 - 592.7 1 2 0 -0.008 19 0 0 0 5.60E+06 8.58E+06 - - - 5.5456 1 221125_WJC_METTL3_EV_vs_WT_F05.24904.24904.4 4.52E-13 26/108 K.GHYTEGAELVDSVLDVVRK.E "sp|Q9BVA1|TBB2B_HUMAN,sp|P07437|TBB5_HUMAN,sp|Q13509|TBB3_HUMAN,sp|Q13885|TBB2A_HUMAN,sp|P68371|TBB4B_HUMAN,tr|A0A0B4J269|A0A0B4J269_HUMAN,tr|Q5ST81|Q5ST81_HUMAN,tr|Q5JP53|Q5JP53_HUMAN,tr|G3V2A3|G3V2A3_HUMAN" 9 2086.0695 0.63 74198 24904 4 2086.062045 522.5246 Tubulin beta-2B chain OS=Homo sapiens OX=9606 GN=TUBB2B PE=1 SV=1 4.75 3956.6 - 488897 - - - -3.566 - 3.974 0.642 - 734.6 1 2 0 -0.0074 19 0 0 0 5.42E+06 8.58E+06 - - - 5.2787 1 221125_WJC_METTL3_EV_vs_WT_F05.24907.24907.3 1.78E-09 24/72 K.GHYTEGAELVDSVLDVVRK.E "sp|Q9BVA1|TBB2B_HUMAN,sp|P07437|TBB5_HUMAN,sp|Q13509|TBB3_HUMAN,sp|Q13885|TBB2A_HUMAN,sp|P68371|TBB4B_HUMAN,tr|A0A0B4J269|A0A0B4J269_HUMAN,tr|Q5ST81|Q5ST81_HUMAN,tr|Q5JP53|Q5JP53_HUMAN,tr|G3V2A3|G3V2A3_HUMAN" 9 2086.0695 0.23 74199 24907 3 2086.063668 696.3638 Tubulin beta-2B chain OS=Homo sapiens OX=9606 GN=TUBB2B PE=1 SV=1 4.75 3957 - 709606 - - - -2.788 - 4.443 0.668 - 921.4 1 2 0 -0.0058 19 0 0 0 3.94E+06 1.71E+07 - - - 9.6498 1 221125_WJC_METTL3_EV_vs_WT_F05.24909.24909.3 1.34E-13 29/72 K.GHYTEGAELVDSVLDVVR[166.11]K[136.11].E "sp|Q9BVA1|TBB2B_HUMAN,sp|P07437|TBB5_HUMAN,sp|Q13509|TBB3_HUMAN,sp|Q13885|TBB2A_HUMAN,sp|P68371|TBB4B_HUMAN,tr|A0A0B4J269|A0A0B4J269_HUMAN,tr|Q5ST81|Q5ST81_HUMAN,tr|Q5JP53|Q5JP53_HUMAN,tr|G3V2A3|G3V2A3_HUMAN" 9 2104.092 0.43 74201 24909 3 2104.085111 702.3713 Tubulin beta-2B chain OS=Homo sapiens OX=9606 GN=TUBB2B PE=1 SV=1 4.75 3957.2 - 1.03E+06 - - - -3.2522 - 4.15 0.72 - 1404.7 1 2 0 -0.0068 19 0 0 0 3.53E+06 8.13E+06 - - - 10.0617 1 221125_WJC_METTL3_EV_vs_WT_F05.24920.24920.4 6.86E-10 16/168 R.TQIAPGSQTVLGIGPGPADLIDK[136.11]VTGHLK[136.11].L "sp|Q9Y3E5|PTH2_HUMAN,tr|J3KQ48|J3KQ48_HUMAN" 2 2898.615 2.26 74207 24920 4 2898.594435 725.661 "Peptidyl-tRNA hydrolase 2, mitochondrial OS=Homo sapiens OX=9606 GN=PTRH2 PE=1 SV=1" 6.41 3958.6 - 184466 - - - -7.0803 - 3.648 0.675 - 113.4 1 2 1 -0.0205 29 0 0 0 1.87E+06 8.30E+05 - - - 5.4944 1 221125_WJC_METTL3_EV_vs_WT_F05.24921.24921.3 3.89E-10 15/60 R.THNLEPYFESFINNLR.R sp|P04264|K2C1_HUMAN 1 1992.9694 26.15 74208 24921 3 1992.96403 665.3304 "Keratin, type II cytoskeletal 1 OS=Homo sapiens OX=9606 GN=KRT1 PE=1 SV=6" 5.37 3958.7 - 309653 - - - -2.6824 - 3.3 0.621 - 356.3 1 2 0 -0.0053 16 0 0 0 1.76E+07 6.73E+05 - - - 8.5255 0.9999 221125_WJC_METTL3_EV_vs_WT_F05.24922.24922.4 7.94E-08 13/222 R.AFGPSETNESPAVVLEPPVVSMEVSEPHILETLKPATK.T sp|P18583|SON_HUMAN 1 4029.0657 999 74209 24922 4 4029.051465 1008.2737 Protein SON OS=Homo sapiens OX=9606 GN=SON PE=1 SV=4 4.47 3958.9 - 289495 - - - -3.5209 - 2.559 0.604 - 49.1 1 2 0 -0.0142 38 0 0 0 9.06E+05 0.00E+00 - - - 4.7533 0.9999 221125_WJC_METTL3_EV_vs_WT_F05.24929.24929.4 8.37E-06 13/108 R.LNEQYEHASIHLWDLLEGK[136.11].E "sp|Q14444|CAPR1_HUMAN,tr|G3V153|G3V153_HUMAN" 2 2302.1473 1.12 74213 24929 4 2302.14041 576.5441 Caprin-1 OS=Homo sapiens OX=9606 GN=CAPRIN1 PE=1 SV=2 4.8 3959.8 - 607903 - - - -3.0133 - 2.324 0.573 - 109.5 1 2 0 -0.0069 19 0 0 0 2.17E+06 1.95E+06 - - - 4.4967 0.9999 221125_WJC_METTL3_EV_vs_WT_F05.24936.24936.4 7.35E-07 23/132 R.GFGFVTYATVEEVDAAMNARPHK.V "sp|P09651|ROA1_HUMAN,tr|A0A7I2YQX9|A0A7I2YQX9_HUMAN,tr|A0A7I2V3W4|A0A7I2V3W4_HUMAN,tr|F8W646|F8W646_HUMAN,tr|F8VZ49|F8VZ49_HUMAN,tr|A0A7I2V3R8|A0A7I2V3R8_HUMAN,tr|F8W6I7|F8W6I7_HUMAN,tr|F8VYN5|F8VYN5_HUMAN,tr|A0A7I2V2L6|A0A7I2V2L6_HUMAN,tr|A0A7I2V3C7|A0A7I2V3C7_HUMAN,tr|A0A7I2V3W0|A0A7I2V3W0_HUMAN,tr|A0A7I2YQV3|A0A7I2YQV3_HUMAN,tr|A0A2R8Y4L2|A0A2R8Y4L2_HUMAN,tr|A0A7I2V2Z4|A0A7I2V2Z4_HUMAN,tr|A0A7I2V4M0|A0A7I2V4M0_HUMAN" 15 2509.206 2.19 74217 24936 4 2509.197521 628.3088 Heterogeneous nuclear ribonucleoprotein A1 OS=Homo sapiens OX=9606 GN=HNRNPA1 PE=1 SV=5 5.45 3960.7 - 727324 - - - -3.3768 - 3.936 0.578 - 360.2 1 2 0 -0.0085 23 0 0 0 2.91E+06 1.33E+06 - - - 4.6985 1 221125_WJC_METTL3_EV_vs_WT_F05.24939.24939.4 7.78E-11 29/114 K.LSSSIIHEIDSILGNKPYSK.K "sp|Q13303|KCAB2_HUMAN,tr|A0A5F9UN28|A0A5F9UN28_HUMAN,tr|A0A590UJB6|A0A590UJB6_HUMAN" 3 2200.1739 1.86 74220 24939 4 2200.169802 551.0508 Voltage-gated potassium channel subunit beta-2 OS=Homo sapiens OX=9606 GN=KCNAB2 PE=1 SV=2 6.75 3961.1 - 716431 - - - -1.8849 - 4.128 0.563 - 615.9 1 2 0 -0.0041 20 0 0 0 1.36E+07 7.29E+06 - - - 4.5992 0.9997 221125_WJC_METTL3_EV_vs_WT_F05.24940.24940.4 0.00115 12/132 R.GFGFVTYATVEEVDAAMNAR[166.11]PHK[136.11].V "sp|P09651|ROA1_HUMAN,tr|A0A7I2YQX9|A0A7I2YQX9_HUMAN,tr|A0A7I2V3W4|A0A7I2V3W4_HUMAN,tr|F8W646|F8W646_HUMAN,tr|F8VZ49|F8VZ49_HUMAN,tr|A0A7I2V3R8|A0A7I2V3R8_HUMAN,tr|F8W6I7|F8W6I7_HUMAN,tr|F8VYN5|F8VYN5_HUMAN,tr|A0A7I2V2L6|A0A7I2V2L6_HUMAN,tr|A0A7I2V3C7|A0A7I2V3C7_HUMAN,tr|A0A7I2V3W0|A0A7I2V3W0_HUMAN,tr|A0A7I2YQV3|A0A7I2YQV3_HUMAN,tr|A0A2R8Y4L2|A0A2R8Y4L2_HUMAN,tr|A0A7I2V2Z4|A0A7I2V2Z4_HUMAN,tr|A0A7I2V4M0|A0A7I2V4M0_HUMAN" 15 2527.2285 2.19 74221 24940 4 2527.219433 632.8144 Heterogeneous nuclear ribonucleoprotein A1 OS=Homo sapiens OX=9606 GN=HNRNPA1 PE=1 SV=5 5.45 3961.2 - 404475 - - - -3.5735 - 2.526 0.447 - 84.9 1 2 0 -0.009 23 0 0 0 2.91E+06 1.33E+06 - - - 3.4144 0.9999 221125_WJC_METTL3_EV_vs_WT_F05.24944.24944.4 1.33E-06 25/114 K.LSSSIIHEIDSILGNK[136.11]PYSK[136.11].K "sp|Q13303|KCAB2_HUMAN,tr|A0A5F9UN28|A0A5F9UN28_HUMAN,tr|A0A590UJB6|A0A590UJB6_HUMAN" 3 2216.2023 1.86 74223 24944 4 2216.193916 555.0579 Voltage-gated potassium channel subunit beta-2 OS=Homo sapiens OX=9606 GN=KCNAB2 PE=1 SV=2 6.75 3961.7 - 1.23E+06 - - - -3.8052 - 3.309 0.53 - 483.7 1 2 0 -0.0084 20 0 0 0 1.36E+07 7.29E+06 - - - 4.2368 0.9766 221125_WJC_METTL3_EV_vs_WT_F05.24954.24954.4 0.063 19/108 R.ADLEMQIESLKEELAYLKK.N sp|P02533|K1C14_HUMAN 1 2250.1817 5.89 74231 24954 4 2250.177424 563.5527 "Keratin, type I cytoskeletal 14 OS=Homo sapiens OX=9606 GN=KRT14 PE=1 SV=4" 4.59 3962.9 - 677933 - - - -1.9163 - 1.906 0.233 - 112.4 1 2 1 -0.0043 19 0 0 0 2.67E+06 4.53E+05 - - - 1.471 0.9942 221125_WJC_METTL3_EV_vs_WT_F05.24963.24963.4 3.43E-11 28/126 M.NVGTRPINLEPIFQGYIDSLKR.Y sp|P35908|K22E_HUMAN 1 2529.3704 562.62 74238 24963 4 2529.363843 633.3499 "Keratin, type II cytoskeletal 2 epidermal OS=Homo sapiens OX=9606 GN=KRT2 PE=1 SV=2" 8.59 3964 - 1.25E+06 - - - -2.5753 - 4.064 0.534 - 465.4 1 1 0 -0.0065 22 0 0 0 8.62E+06 1.53E+04 - - - 4.3309 1 221125_WJC_METTL3_EV_vs_WT_F05.24974.24974.3 5.57E-09 11/100 R.SGPFGQIFRPDNFVFGQSGAGNNWAK.G "sp|P04350|TBB4A_HUMAN,sp|Q9BVA1|TBB2B_HUMAN,sp|P07437|TBB5_HUMAN,sp|Q13885|TBB2A_HUMAN,sp|P68371|TBB4B_HUMAN,tr|Q5ST81|Q5ST81_HUMAN,tr|Q5JP53|Q5JP53_HUMAN,tr|M0QY85|M0QY85_HUMAN,tr|M0QZL7|M0QZL7_HUMAN,tr|M0R278|M0R278_HUMAN,tr|M0R1I1|M0R1I1_HUMAN" 11 2797.3361 0.95 74246 24974 3 2797.331635 933.4526 Tubulin beta-4A chain OS=Homo sapiens OX=9606 GN=TUBB4A PE=1 SV=2 8.46 3965.4 - 249290 - - - -1.5951 - 2.966 0.618 - 116.1 1 2 0 -0.0045 26 0 0 0 1.30E+06 1.37E+06 - - - 7.9301 0.9977 221125_WJC_METTL3_EV_vs_WT_F05.24975.24975.3 1.81E-06 16/84 M.NVGTRPINLEPIFQGYIDSLKR.Y sp|P35908|K22E_HUMAN 1 2529.3704 999 74247 24975 3 2529.367003 844.1307 "Keratin, type II cytoskeletal 2 epidermal OS=Homo sapiens OX=9606 GN=KRT2 PE=1 SV=2" 8.59 3965.6 - 245068 - - - -1.326 - 2.877 0.546 - 234.4 1 1 0 -0.0034 22 0 0 0 1.56E+06 0.00E+00 - - - 7.1318 0.9999 221125_WJC_METTL3_EV_vs_WT_F05.24976.24976.3 1.14E-08 Dec-84 R.K[136.11]PLVIIAEDVDGEALSTLVLNR[166.11].L "sp|P10809|CH60_HUMAN,tr|A0A7I2V2X6|A0A7I2V2X6_HUMAN,tr|A0A7I2YQK6|A0A7I2YQK6_HUMAN,tr|A0A7I2V599|A0A7I2V599_HUMAN,tr|A0A7I2YQ71|A0A7I2YQ71_HUMAN,tr|A0A7I2V5M1|A0A7I2V5M1_HUMAN,tr|A0A7I2V5K3|A0A7I2V5K3_HUMAN" 7 2382.3489 1.34 74248 24976 3 2382.339121 795.1236 "60 kDa heat shock protein, mitochondrial OS=Homo sapiens OX=9606 GN=HSPD1 PE=1 SV=2" 4.32 3965.7 - 222186 - - - -4.1035 - 2.844 0.624 - 155.9 1 2 0 -0.0098 22 0 0 0 2.26E+06 1.69E+06 - - - 7.9723 0.9996 221125_WJC_METTL3_EV_vs_WT_F05.24981.24981.2 0.000201 22-Dec R.NLDLDSIIAEVK.A "sp|P48668|K2C6C_HUMAN,sp|P04259|K2C6B_HUMAN,sp|P13647|K2C5_HUMAN,sp|P35908|K22E_HUMAN,sp|O95678|K2C75_HUMAN,sp|Q5XKE5|K2C79_HUMAN,sp|P02538|K2C6A_HUMAN,tr|H0YI76|H0YI76_HUMAN,tr|H0YIN9|H0YIN9_HUMAN" 9 1328.7187 189.4 74251 24981 2 1328.715424 665.3666 "Keratin, type II cytoskeletal 6C OS=Homo sapiens OX=9606 GN=KRT6C PE=1 SV=3" 4.03 3966.4 - 915523 - - - -2.5009 - 2.328 0.494 - 325 1 2 0 -0.0033 12 0 0 0 5.44E+06 2.87E+04 - - - 4.912 0.9997 221125_WJC_METTL3_EV_vs_WT_F05.24982.24982.4 0.000368 7/108 R.TDLEMQIEGLKEELAYLRK.N sp|P08779|K1C16_HUMAN 1 2278.1879 28.47 74252 24982 4 2278.185225 570.5542 "Keratin, type I cytoskeletal 16 OS=Homo sapiens OX=9606 GN=KRT16 PE=1 SV=4" 4.58 3966.5 - 139015 - - - -1.1672 - 2.107 0.447 - 41.4 1 2 1 -0.0027 19 0 0 0 3.18E+06 1.12E+05 - - - 3.3681 1 221125_WJC_METTL3_EV_vs_WT_F05.24983.24983.4 2.12E-11 19/258 R.FGGFGGPGGVGGLGGPGGFGPGGYPGGIHEVSVNQSLLQPLNVK.V sp|P35908|K22E_HUMAN 1 4091.0653 999 74253 24983 4 4091.057633 1023.7736 "Keratin, type II cytoskeletal 2 epidermal OS=Homo sapiens OX=9606 GN=KRT2 PE=1 SV=2" 6.75 3966.7 - 415882 - - - -1.8861 - 3.483 0.674 - 82.2 1 2 0 -0.0077 44 0 0 0 2.08E+06 0.00E+00 - - - 5.4439 1 221125_WJC_METTL3_EV_vs_WT_F05.24984.24984.3 2.72E-13 15/100 R.SGPFGQIFR[166.11]PDNFVFGQSGAGNNWAK[136.11].G "sp|P04350|TBB4A_HUMAN,sp|Q9BVA1|TBB2B_HUMAN,sp|P07437|TBB5_HUMAN,sp|Q13885|TBB2A_HUMAN,sp|P68371|TBB4B_HUMAN,tr|Q5ST81|Q5ST81_HUMAN,tr|Q5JP53|Q5JP53_HUMAN,tr|M0QY85|M0QY85_HUMAN,tr|M0QZL7|M0QZL7_HUMAN,tr|M0R278|M0R278_HUMAN,tr|M0R1I1|M0R1I1_HUMAN" 11 2815.3586 0.95 74254 24984 3 2815.352016 939.4601 Tubulin beta-4A chain OS=Homo sapiens OX=9606 GN=TUBB4A PE=1 SV=2 8.46 3966.8 - 238751 - - - -2.3269 - 3.356 0.625 - 234.8 1 2 0 -0.0066 26 0 0 0 1.30E+06 1.37E+06 - - - 8.2918 1 221125_WJC_METTL3_EV_vs_WT_F05.24985.24985.3 4.26E-06 19/84 R.KPLVIIAEDVDGEALSTLVLNR.L "sp|P10809|CH60_HUMAN,tr|A0A7I2V2X6|A0A7I2V2X6_HUMAN,tr|A0A7I2YQK6|A0A7I2YQK6_HUMAN,tr|A0A7I2V599|A0A7I2V599_HUMAN,tr|A0A7I2YQ71|A0A7I2YQ71_HUMAN,tr|A0A7I2V5M1|A0A7I2V5M1_HUMAN,tr|A0A7I2V5K3|A0A7I2V5K3_HUMAN" 7 2364.3264 1.38 74255 24985 3 2364.325688 789.1161 "60 kDa heat shock protein, mitochondrial OS=Homo sapiens OX=9606 GN=HSPD1 PE=1 SV=2" 4.32 3966.9 - 211268 - - - -0.3126 - 3.768 0.634 - 463.9 1 2 0 -0.0007 22 0 0 0 2.33E+06 1.69E+06 - - - 8.7533 0.9791 221125_WJC_METTL3_EV_vs_WT_F05.24986.24986.4 0.00187 Aug-90 K.STSESFIQHIVSLVHH.V "sp|Q9NYF8|BCLF1_HUMAN,tr|E9PKI6|E9PKI6_HUMAN,tr|A0A1W2PQ43|A0A1W2PQ43_HUMAN,tr|E9PK91|E9PK91_HUMAN,tr|E9PJA7|E9PJA7_HUMAN,tr|E9PK09|E9PK09_HUMAN,tr|E9PQN2|E9PQN2_HUMAN" 7 1819.9217 - 74256 24986 4 1819.918063 455.9877 Bcl-2-associated transcription factor 1 OS=Homo sapiens OX=9606 GN=BCLAF1 PE=1 SV=2 6.2 3967.1 - 205557 - - - -1.9968 - 1.891 0.417 - 51 1 1 0 -0.0036 16 0 0 0 - - - - - 3.079 0.8783 221125_WJC_METTL3_EV_vs_WT_F05.24996.24996.3 1.08E-07 18/80 K.R[166.11]R[166.11]AEQDSTTVAAFASSLVSGL.N "sp|Q86U44|MTA70_HUMAN,tr|F5H6D8|F5H6D8_HUMAN,tr|H0YFV6|H0YFV6_HUMAN,tr|B4DTN4|B4DTN4_HUMAN" 4 2185.1242 0 74264 24996 3 2185.115811 729.382 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 6.07 3968.3 - 1.07E+07 - - - -3.8391 - 2.928 0.449 - 340.3 1 1 1 -0.0084 21 0 0 0 2.48E+05 6.61E+07 - - - 6.1192 0.9999 221125_WJC_METTL3_EV_vs_WT_F05.25000.25000.4 8.46E-06 16/114 K.NVVHQLSVTLEDLYNGATR[166.11]K[136.11].L sp|P31689|DNJA1_HUMAN 1 2274.2087 0.6 74268 25000 4 2274.20077 569.5595 DnaJ homolog subfamily A member 1 OS=Homo sapiens OX=9606 GN=DNAJA1 PE=1 SV=2 6.75 3968.8 - 238820 - - - -3.4935 - 2.714 0.517 - 194.8 1 2 0 -0.0079 20 0 0 0 8.21E+05 1.36E+06 - - - 4.0576 0.9995 221125_WJC_METTL3_EV_vs_WT_F05.25002.25002.3 3.82E-08 9/116 K.DMAIATGGAVFGEEGLTLNLEDVQPHDLGK[136.11].V "sp|P10809|CH60_HUMAN,tr|A0A7I2V2X6|A0A7I2V2X6_HUMAN,tr|A0A7I2YQK6|A0A7I2YQK6_HUMAN,tr|A0A7I2V599|A0A7I2V599_HUMAN" 4 3104.5216 2.32 74270 25002 3 3104.502887 1035.8478 "60 kDa heat shock protein, mitochondrial OS=Homo sapiens OX=9606 GN=HSPD1 PE=1 SV=2" 4.01 3969.1 - 143630 - - - -6.0215 - 2.33 0.628 - 47.6 1 2 0 -0.0187 30 0 0 0 5.54E+06 2.39E+06 - - - 7.4824 1 221125_WJC_METTL3_EV_vs_WT_F05.25006.25006.3 6.02E-09 17/76 K.NVVHQLSVTLEDLYNGATR[166.11]K[136.11].L sp|P31689|DNJA1_HUMAN 1 2274.2087 0.28 74272 25006 3 2274.205542 759.0768 DnaJ homolog subfamily A member 1 OS=Homo sapiens OX=9606 GN=DNAJA1 PE=1 SV=2 6.75 3969.6 - 320652 - - - -1.3952 - 4.033 0.586 - 376.8 1 2 0 -0.0032 20 0 0 0 2.66E+05 9.57E+05 - - - 8.4556 1 221125_WJC_METTL3_EV_vs_WT_F05.25007.25007.4 1.75E-10 17/204 R.LC[160.03]QADPDLDSDKDETGAYLIDRDPTYFGPVLNYLR.H "sp|Q9NXV2|KCTD5_HUMAN,tr|H3BSS5|H3BSS5_HUMAN" 2 4044.9051 16.62 74273 25007 4 4044.889712 1012.2336 BTB\POZ domain-containing protein KCTD5 OS=Homo sapiens OX=9606 GN=KCTD5 PE=1 SV=1 3.94 3969.7 - 512462 - - - -3.8112 - 3.278 0.639 - 59.4 1 2 2 -0.0154 35 0 0 0 3.88E+06 2.33E+05 - - - 5.1356 0.9993 221125_WJC_METTL3_EV_vs_WT_F05.25010.25010.4 8.10E-06 9/144 R.NAAENMLEILGFK[136.11]VPQAQPTK[136.11]PALK[136.11].S "sp|O95793|STAU1_HUMAN,tr|Q5JW30|Q5JW30_HUMAN" 2 2731.5157 1.6 74276 25010 4 2731.504775 683.8862 Double-stranded RNA-binding protein Staufen homolog 1 OS=Homo sapiens OX=9606 GN=STAU1 PE=1 SV=2 8.5 3970.1 - 150412 - - - -4.0025 - 2.033 0.543 - 36.9 1 2 1 -0.0109 25 0 0 0 1.28E+06 7.99E+05 - - - 4.175 0.9999 221125_WJC_METTL3_EV_vs_WT_F05.25015.25015.3 1.82E-11 9/116 K.DMAIATGGAVFGEEGLTLNLEDVQPHDLGK.V "sp|P10809|CH60_HUMAN,tr|A0A7I2V2X6|A0A7I2V2X6_HUMAN,tr|A0A7I2YQK6|A0A7I2YQK6_HUMAN,tr|A0A7I2V599|A0A7I2V599_HUMAN" 4 3096.5074 1.49 74279 25015 3 3096.500437 1033.1764 "60 kDa heat shock protein, mitochondrial OS=Homo sapiens OX=9606 GN=HSPD1 PE=1 SV=2" 4.01 3970.8 - 252168 - - - -2.2425 - 2.548 0.538 - 44.6 1 2 0 -0.0069 30 0 0 0 1.84E+06 1.23E+06 - - - 6.6881 0.847 221125_WJC_METTL3_EV_vs_WT_F05.25020.25020.3 0.00218 7/104 K.AQSSQDPANLFSLPPLPPPPLPAGGSR.P sp|Q8N5Z5|KCD17_HUMAN 1 2710.4079 50.65 74282 25020 3 2710.400347 904.4766 BTB\POZ domain-containing protein KCTD17 OS=Homo sapiens OX=9606 GN=KCTD17 PE=1 SV=3 5.88 3971.5 - 133392 - - - -2.7738 - 1.794 0.348 - 44.1 1 1 0 -0.0075 27 0 0 0 1.95E+06 3.84E+04 - - - 3.7624 0.9998 221125_WJC_METTL3_EV_vs_WT_F05.25029.25029.4 3.65E-05 10/108 K.FNLLAHLADDLGHVVPNSR[166.11].L sp|Q8N5N7|RM50_HUMAN 1 2097.0995 1.81 74289 25029 4 2097.094412 525.2821 "39S ribosomal protein L50, mitochondrial OS=Homo sapiens OX=9606 GN=MRPL50 PE=1 SV=2" 5.98 3972.7 - 73109.1 - - - -2.4224 - 2.077 0.422 - 62.5 1 2 0 -0.0051 19 0 0 0 7.97E+05 4.39E+05 - - - 3.1449 1 221125_WJC_METTL3_EV_vs_WT_F05.25038.25038.3 3.10E-07 Dec-68 R.GDADQASNILASFGLSAR.D "sp|P43243|MATR3_HUMAN,tr|A8MXP9|A8MXP9_HUMAN,tr|D6R991|D6R991_HUMAN,tr|A0A0R4J2E8|A0A0R4J2E8_HUMAN,tr|D6REM6|D6REM6_HUMAN" 5 1791.8751 1.27 74296 25038 3 1791.875103 598.299 Matrin-3 OS=Homo sapiens OX=9606 GN=MATR3 PE=1 SV=2 4.21 3973.9 - 226909 - - - -0.0212 - 2.351 0.592 - 174 1 2 0 0 18 0 0 0 1.61E+06 1.27E+06 - - - 7.2688 0.9991 221125_WJC_METTL3_EV_vs_WT_F05.25039.25039.3 0.00699 Aug-60 R.QNLEPLFEQYINNLRR.Q "sp|P48668|K2C6C_HUMAN,sp|P04259|K2C6B_HUMAN,sp|P13647|K2C5_HUMAN,sp|P02538|K2C6A_HUMAN,tr|F8W0C6|F8W0C6_HUMAN" 5 2046.0647 81.9 74297 25039 3 2046.067241 683.0288 "Keratin, type II cytoskeletal 6C OS=Homo sapiens OX=9606 GN=KRT6C PE=1 SV=3" 6.14 3974.1 - 63597.6 - - - 1.2551 - 1.533 0.355 - 66.9 1 2 0 0.0026 16 0 0 0 7.79E+05 9.51E+03 - - - 3.5934 1 221125_WJC_METTL3_EV_vs_WT_F05.25040.25040.2 2.08E-13 13/34 R.GDADQASNILASFGLSAR.D "sp|P43243|MATR3_HUMAN,tr|A8MXP9|A8MXP9_HUMAN,tr|D6R991|D6R991_HUMAN,tr|A0A0R4J2E8|A0A0R4J2E8_HUMAN,tr|D6REM6|D6REM6_HUMAN" 5 1791.8751 1.37 74298 25040 2 1791.874907 896.9448 Matrin-3 OS=Homo sapiens OX=9606 GN=MATR3 PE=1 SV=2 4.21 3974.2 - 187454 - - - -0.1306 - 3.115 0.68 - 441.4 1 2 0 -0.0002 18 0 0 0 1.69E+06 1.23E+06 - - - 6.8569 1 221125_WJC_METTL3_EV_vs_WT_F05.25046.25046.3 1.61E-05 Nov-68 R.GDADQASNILASFGLSAR[166.11].D "sp|P43243|MATR3_HUMAN,tr|A8MXP9|A8MXP9_HUMAN,tr|D6R991|D6R991_HUMAN,tr|A0A0R4J2E8|A0A0R4J2E8_HUMAN,tr|D6REM6|D6REM6_HUMAN" 5 1801.8834 1.27 74302 25046 3 1801.882327 601.6351 Matrin-3 OS=Homo sapiens OX=9606 GN=MATR3 PE=1 SV=2 4.21 3975 - 220775 - - - -0.6016 - 2.191 0.497 - 133.9 1 2 0 -0.0011 18 0 0 0 1.61E+06 1.27E+06 - - - 6.0339 0.9983 221125_WJC_METTL3_EV_vs_WT_F05.25048.25048.3 2.12E-08 18/80 N.WITLGNQLDGIHLLDPDVVAR[166.11].F sp|Q86U44|MTA70_HUMAN 1 2354.2622 0.01 74304 25048 3 2354.262456 785.7613 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 4.41 3975.3 - 324522 - - - 0.1087 - 3.076 0.549 - 209.6 1 1 0 0.0003 21 0 0 0 1.16E+05 8.27E+06 - - - 7.3546 0.9999 221125_WJC_METTL3_EV_vs_WT_F05.25050.25050.4 0.00014 10/252 K.QPVPVGGAISTAQAQAFLGHLHQVQLAGTSLQAAAQSLNVQSK.S "sp|P14859|PO2F1_HUMAN,tr|A0A0A0MT46|A0A0A0MT46_HUMAN" 2 4321.2931 2.31 74306 25050 4 4321.294749 1081.3306 "POU domain, class 2, transcription factor 1 OS=Homo sapiens OX=9606 GN=POU2F1 PE=1 SV=2" 8.76 3975.5 - 68654.5 - - - 0.3777 - 2.286 0.469 - 39.7 1 2 0 0.0016 43 0 0 0 5.14E+05 2.23E+05 - - - 3.543 0.9997 221125_WJC_METTL3_EV_vs_WT_F05.25059.25059.3 1.50E-05 7/108 K.NIILEEGKEILVGDVGQTVDDPYATFVK.M "sp|P23528|COF1_HUMAN,tr|E9PP50|E9PP50_HUMAN,tr|G3V1A4|G3V1A4_HUMAN,tr|E9PQB7|E9PQB7_HUMAN,tr|E9PK25|E9PK25_HUMAN,tr|E9PLJ3|E9PLJ3_HUMAN,tr|E9PS23|E9PS23_HUMAN" 7 3061.5859 -1 74312 25059 3 3061.585176 1021.5359 Cofilin-1 OS=Homo sapiens OX=9606 GN=CFL1 PE=1 SV=3 4.02 3976.8 - 60235.7 - - - -0.2525 - 1.657 0.54 - 26.2 1 2 1 -0.0008 28 0 0 0 0.00E+00 0.00E+00 - - - 5.7221 1 221125_WJC_METTL3_EV_vs_WT_F05.25061.25061.4 2.77E-06 9/180 K.TIFTGHTAVVEDVSWHLLHESLFGSVADDQK.L sp|Q09028|RBBP4_HUMAN 1 3437.6892 0.91 74314 25061 4 3437.691813 860.4296 Histone-binding protein RBBP4 OS=Homo sapiens OX=9606 GN=RBBP4 PE=1 SV=3 4.77 3977.1 - 107263 - - - 0.7645 - 2.009 0.521 - 36.5 1 2 0 0.0026 31 0 0 0 5.78E+05 6.37E+05 - - - 3.9721 0.8221 221125_WJC_METTL3_EV_vs_WT_F05.25063.25063.3 1.3 Apr-68 K.DGVFLYFEDNAGVIVNNK[136.11].G "sp|P62829|RL23_HUMAN,tr|J3KT29|J3KT29_HUMAN,tr|J3KTJ3|J3KTJ3_HUMAN" 3 2020.9986 1.28 74316 25063 3 2020.996238 674.6735 60S ribosomal protein L23 OS=Homo sapiens OX=9606 GN=RPL23 PE=1 SV=1 4.03 3977.3 - 40798.9 - - - -1.1475 - 1.048 0.164 - 12.4 6 2 0 -0.0023 18 0 0 0 4.21E+05 3.29E+05 - - - 0.1244 0.9996 221125_WJC_METTL3_EV_vs_WT_F05.25067.25067.3 2.71E-08 16/76 K.HAASDVDLEIESLLNQQSTK[136.11].E "sp|Q86U44|MTA70_HUMAN,tr|F5H6D8|F5H6D8_HUMAN,tr|H0YFV6|H0YFV6_HUMAN,tr|B4DTN4|B4DTN4_HUMAN" 4 2205.1005 0.04 74318 25067 3 2206.101072 736.0408 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 4.31 3977.9 - 175645 - - - 453.7734 - 3.641 0.602 - 345.2 1 2 0 1.0006 20 0 0 0 3.40E+05 8.49E+06 - - - 8.1096 1 221125_WJC_METTL3_EV_vs_WT_F05.25069.25069.4 3.08E-06 17/90 R.RDSHLTLLNQLLQGLR.Q "sp|Q9NRX2|RM17_HUMAN,tr|E9PKV2|E9PKV2_HUMAN" 2 1876.0643 1.19 74320 25069 4 1876.063991 470.0233 "39S ribosomal protein L17, mitochondrial OS=Homo sapiens OX=9606 GN=MRPL17 PE=1 SV=1" 9.61 3978.2 - 125726 - - - -0.1535 - 3.257 0.567 - 349.9 1 2 0 -0.0003 16 0 0 0 5.51E+05 4.62E+05 - - - 4.577 1 221125_WJC_METTL3_EV_vs_WT_F05.25070.25070.3 4.70E-08 Dec-60 R.RDSHLTLLNQLLQGLR.Q "sp|Q9NRX2|RM17_HUMAN,tr|E9PKV2|E9PKV2_HUMAN" 2 1876.0643 1.36 74321 25070 3 1876.06578 626.362 "39S ribosomal protein L17, mitochondrial OS=Homo sapiens OX=9606 GN=MRPL17 PE=1 SV=1" 9.61 3978.3 - 101912 - - - 0.8001 - 2.356 0.586 - 207.8 1 2 0 0.0015 16 0 0 0 5.99E+05 4.42E+05 - - - 7.2718 0.9113 221125_WJC_METTL3_EV_vs_WT_F05.25078.25078.3 0.509 May-72 G.VTIAQGGVLPNIQAVLLPK.K "sp|P16104|H2AX_HUMAN,sp|Q9BTM1|H2AJ_HUMAN,sp|Q93077|H2A1C_HUMAN,sp|Q99878|H2A1J_HUMAN,sp|Q16777|H2A2C_HUMAN,sp|Q8IUE6|H2A2B_HUMAN,sp|Q96QV6|H2A1A_HUMAN,sp|P04908|H2A1B_HUMAN,sp|P20671|H2A1D_HUMAN,sp|P0C0S8|H2A1_HUMAN,sp|Q6FI13|H2A2A_HUMAN,sp|Q96KK5|H2A1H_HUMAN,sp|Q7L7L0|H2A3_HUMAN,tr|A0A0U1RR32|A0A0U1RR32_HUMAN,tr|A0A0U1RRH7|A0A0U1RRH7_HUMAN,tr|H0YFX9|H0YFX9_HUMAN" 16 1930.1615 1.42 74327 25078 3 1930.164812 644.3945 Histone H2AX OS=Homo sapiens OX=9606 GN=H2AX PE=1 SV=2 8.72 3979.4 - 86220.2 - - - 1.6983 - 1.103 0.443 - 23.6 1 1 0 0.0033 19 0 0 0 1.41E+06 9.95E+05 - - - 3.7189 0.9997 221125_WJC_METTL3_EV_vs_WT_F05.25079.25079.2 0.000112 24-Jun R.FSGSGSGTDFTLK.L "sp|A2NJV5|KV229_HUMAN,sp|A0A087WW87|KV240_HUMAN,sp|P06310|KV230_HUMAN,sp|A0A075B6S2|KVD29_HUMAN,sp|P01614|KVD40_HUMAN,sp|P01615|KVD28_HUMAN,sp|A0A075B6S6|KVD30_HUMAN,sp|A0A075B6P5|KV228_HUMAN,sp|A0A0A0MRZ7|KVD26_HUMAN" 9 1302.6092 9.96 74328 25079 2 1302.609877 652.3119 Immunoglobulin kappa variable 2-29 OS=Homo sapiens OX=9606 GN=IGKV2-29 PE=3 SV=2 5.84 3979.5 - 62355 - - - 0.5228 - 1.425 0.53 - 50.6 1 2 0 0.0007 13 0 0 0 4.21E+06 4.23E+05 - - - 3.8644 0.817 221125_WJC_METTL3_EV_vs_WT_F05.25080.25080.3 0.0369 Jul-72 G.VTIAQGGVLPNIQAVLLPK[136.11].K "sp|P16104|H2AX_HUMAN,sp|Q9BTM1|H2AJ_HUMAN,sp|Q93077|H2A1C_HUMAN,sp|Q99878|H2A1J_HUMAN,sp|Q16777|H2A2C_HUMAN,sp|Q8IUE6|H2A2B_HUMAN,sp|Q96QV6|H2A1A_HUMAN,sp|P04908|H2A1B_HUMAN,sp|P20671|H2A1D_HUMAN,sp|P0C0S8|H2A1_HUMAN,sp|Q6FI13|H2A2A_HUMAN,sp|Q96KK5|H2A1H_HUMAN,sp|Q7L7L0|H2A3_HUMAN,tr|A0A0U1RR32|A0A0U1RR32_HUMAN,tr|A0A0U1RRH7|A0A0U1RRH7_HUMAN,tr|H0YFX9|H0YFX9_HUMAN" 16 1938.1757 1.42 74329 25080 3 1938.174984 647.0659 Histone H2AX OS=Homo sapiens OX=9606 GN=H2AX PE=1 SV=2 8.72 3979.6 - 53282.6 - - - -0.387 - 1.472 0.296 - 39.6 1 1 0 -0.0007 19 0 0 0 1.41E+06 9.95E+05 - - - 2.7898 0.9974 221125_WJC_METTL3_EV_vs_WT_F05.25086.25086.3 4.98E-09 Oct-68 K.GHYTEGAELVDSVLDVVR[166.11].K "sp|Q9BVA1|TBB2B_HUMAN,sp|P07437|TBB5_HUMAN,sp|Q13509|TBB3_HUMAN,sp|Q13885|TBB2A_HUMAN,sp|P68371|TBB4B_HUMAN,tr|A0A0B4J269|A0A0B4J269_HUMAN,tr|Q5ST81|Q5ST81_HUMAN,tr|Q5JP53|Q5JP53_HUMAN,tr|G3V2A3|G3V2A3_HUMAN" 9 1967.9828 0.86 74333 25086 3 1968.981055 657.0015 Tubulin beta-2B chain OS=Homo sapiens OX=9606 GN=TUBB2B PE=1 SV=1 4.31 3980.5 - 73928.6 - - - 507.2524 - 2.394 0.537 - 151.5 1 2 0 0.9983 18 0 0 0 6.05E+05 7.01E+05 - - - 6.4243 1 221125_WJC_METTL3_EV_vs_WT_F05.25091.25091.4 2.84E-06 11/126 R.KPLVIIAEDVDGEALSTLVLNR.L "sp|P10809|CH60_HUMAN,tr|A0A7I2V2X6|A0A7I2V2X6_HUMAN,tr|A0A7I2YQK6|A0A7I2YQK6_HUMAN,tr|A0A7I2V599|A0A7I2V599_HUMAN,tr|A0A7I2YQ71|A0A7I2YQ71_HUMAN,tr|A0A7I2V5M1|A0A7I2V5M1_HUMAN,tr|A0A7I2V5K3|A0A7I2V5K3_HUMAN" 7 2364.3264 1.58 74334 25091 4 2364.328837 592.0889 "60 kDa heat shock protein, mitochondrial OS=Homo sapiens OX=9606 GN=HSPD1 PE=1 SV=2" 4.32 3981.2 - 95056.7 - - - 1.0193 - 2.42 0.542 - 90.1 1 2 0 0.0024 22 0 0 0 3.55E+06 2.25E+06 - - - 4.2321 1 221125_WJC_METTL3_EV_vs_WT_F05.25092.25092.4 1.66E-06 8/126 R.K[136.11]PLVIIAEDVDGEALSTLVLNR[166.11].L "sp|P10809|CH60_HUMAN,tr|A0A7I2V2X6|A0A7I2V2X6_HUMAN,tr|A0A7I2YQK6|A0A7I2YQK6_HUMAN,tr|A0A7I2V599|A0A7I2V599_HUMAN,tr|A0A7I2YQ71|A0A7I2YQ71_HUMAN,tr|A0A7I2V5M1|A0A7I2V5M1_HUMAN,tr|A0A7I2V5K3|A0A7I2V5K3_HUMAN" 7 2382.3489 1.58 74335 25092 4 2382.346153 596.5945 "60 kDa heat shock protein, mitochondrial OS=Homo sapiens OX=9606 GN=HSPD1 PE=1 SV=2" 4.32 3981.4 - 53312.2 - - - -1.1518 - 1.868 0.531 - 38.3 1 2 0 -0.0027 22 0 0 0 3.55E+06 2.25E+06 - - - 4.0515 0.9995 221125_WJC_METTL3_EV_vs_WT_F05.25100.25100.4 0.00392 Jun-90 R.THNLEPYFESFINNLR.R sp|P04264|K2C1_HUMAN 1 1992.9694 45.58 74341 25100 4 1992.96951 499.2496 "Keratin, type II cytoskeletal 1 OS=Homo sapiens OX=9606 GN=KRT1 PE=1 SV=6" 5.37 3982.4 - 74556 - - - 0.0672 - 1.258 0.356 - 31 1 2 0 0.0001 16 0 0 0 1.61E+06 3.53E+04 - - - 2.4054 0.9999 221125_WJC_METTL3_EV_vs_WT_F05.25104.25104.3 5.76E-05 Aug-60 K.K[136.11]VSQEILELLNTTTAK[136.11].E "sp|Q86U44|MTA70_HUMAN,tr|H0YFV6|H0YFV6_HUMAN" 2 1803.0324 0.01 74344 25104 3 1803.03344 602.0181 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 6.14 3982.9 - 138592 - - - 0.5602 - 1.887 0.492 - 76.4 1 2 0 0.001 16 0 0 0 4.63E+04 5.73E+06 - - - 5.6543 1 221125_WJC_METTL3_EV_vs_WT_F05.25106.25106.3 2.43E-06 Sep-72 K.K[136.11]FESEILEAISQNSVVIIR[166.11].G sp|Q08211|DHX9_HUMAN 1 2192.2172 0.83 74345 25106 3 2192.216218 731.7463 ATP-dependent RNA helicase A OS=Homo sapiens OX=9606 GN=DHX9 PE=1 SV=4 4.79 3983.2 - 86217.9 - - - -0.427 - 2.422 0.542 - 82.1 1 2 0 -0.0009 19 0 0 0 2.79E+05 3.36E+05 - - - 6.7558 1 221125_WJC_METTL3_EV_vs_WT_F05.25111.25111.3 3.87E-07 Nov-72 K.KFESEILEAISQNSVVIIR.G sp|Q08211|DHX9_HUMAN 1 2174.1947 0.83 74349 25111 3 2174.19179 725.7388 ATP-dependent RNA helicase A OS=Homo sapiens OX=9606 GN=DHX9 PE=1 SV=4 4.79 3983.8 - 89690.7 - - - -1.3311 - 2.509 0.612 - 168.2 1 2 0 -0.0029 19 0 0 0 2.79E+05 3.36E+05 - - - 7.6224 0.9999 221125_WJC_METTL3_EV_vs_WT_F05.25112.25112.2 5.60E-06 30-Aug R.THNLEPYFESFINNLR.R sp|P04264|K2C1_HUMAN 1 1992.9694 999 74350 25112 2 1992.966527 997.492 "Keratin, type II cytoskeletal 1 OS=Homo sapiens OX=9606 GN=KRT1 PE=1 SV=6" 5.37 3983.9 - 84933.4 - - - -1.4295 - 2.06 0.603 - 165.8 1 2 0 -0.0028 16 0 0 0 7.42E+05 0.00E+00 - - - 5.2707 1 221125_WJC_METTL3_EV_vs_WT_F05.25120.25120.4 2.42E-07 22/174 K.IVKPNGEKPDEFESGISQALLELEMNSDLK.A "sp|P62081|RS7_HUMAN,tr|B5MCP9|B5MCP9_HUMAN,tr|A0A2R8Y623|A0A2R8Y623_HUMAN" 3 3329.6701 0.78 74356 25120 4 3329.662232 833.4248 40S ribosomal protein S7 OS=Homo sapiens OX=9606 GN=RPS7 PE=1 SV=1 4.25 3984.9 - 597010 - - - -2.3597 - 4.107 0.608 - 276.4 1 2 0 -0.0079 30 0 0 0 4.71E+06 6.04E+06 - - - 4.9481 0.9999 221125_WJC_METTL3_EV_vs_WT_F05.25122.25122.3 8.26E-05 7/100 R.EIQLWFQSSELVSWADGGQHSSIHPA.- "sp|O00746|NDKM_HUMAN,tr|Q4TT34|Q4TT34_HUMAN,tr|A0A087WVT9|A0A087WVT9_HUMAN" 3 2908.378 - 74358 25122 3 2908.375144 970.4666 "Nucleoside diphosphate kinase, mitochondrial OS=Homo sapiens OX=9606 GN=NME4 PE=1 SV=1" 4.63 3985.1 - 79894.8 - - - -0.9892 - 1.666 0.545 - 34.9 1 2 0 -0.0029 26 0 0 0 - - - - - 5.7897 1 221125_WJC_METTL3_EV_vs_WT_F05.25132.25132.4 1.54E-09 19/174 K.IVK[136.11]PNGEK[136.11]PDEFESGISQALLELEMNSDLK[136.11].A "sp|P62081|RS7_HUMAN,tr|B5MCP9|B5MCP9_HUMAN,tr|A0A2R8Y623|A0A2R8Y623_HUMAN" 3 3353.7127 0.78 74364 25132 4 3353.707383 839.4354 40S ribosomal protein S7 OS=Homo sapiens OX=9606 GN=RPS7 PE=1 SV=1 4.25 3986.5 - 627967 - - - -1.5821 - 3.734 0.568 - 231.9 1 2 0 -0.0053 30 0 0 0 4.71E+06 6.04E+06 - - - 4.5716 1 221125_WJC_METTL3_EV_vs_WT_F05.25149.25149.3 3.05E-10 14/92 K.HYQEEGQGTEVVQGVLLGLVVEDR[166.11].L "sp|O15372|EIF3H_HUMAN,tr|B3KS98|B3KS98_HUMAN,tr|A0A087WZK9|A0A087WZK9_HUMAN,tr|E5RFW7|E5RFW7_HUMAN,tr|E5RFH0|E5RFH0_HUMAN,tr|E5RGU4|E5RGU4_HUMAN" 6 2663.343 2.5 74374 25149 3 2663.343185 888.7883 Eukaryotic translation initiation factor 3 subunit H OS=Homo sapiens OX=9606 GN=EIF3H PE=1 SV=1 4.25 3988.9 - 50323.4 - - - 0.0582 - 2.852 0.681 - 173.9 1 2 0 0.0002 24 0 0 0 5.81E+05 2.32E+05 - - - 8.5666 0.9964 221125_WJC_METTL3_EV_vs_WT_F05.25152.25152.3 0.0157 Jun-60 R.THNLEPYFESFINNLR.R sp|P04264|K2C1_HUMAN 1 1992.9694 1976.24 74376 25152 3 1992.97271 665.3304 "Keratin, type II cytoskeletal 1 OS=Homo sapiens OX=9606 GN=KRT1 PE=1 SV=6" 5.37 3989.3 - 24243.9 - - - 1.6729 - 1.478 0.287 - 47 1 2 0 0.0033 16 0 0 0 3.01E+07 1.52E+04 - - - 2.7413 0.9102 221125_WJC_METTL3_EV_vs_WT_F05.25162.25162.3 1.08E-06 13/80 N.WITLGNQLDGIHLLDPDVVAR.F sp|Q86U44|MTA70_HUMAN 1 2344.2539 0.02 74383 25162 3 2345.25354 782.4253 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 4.41 3990.7 - 103861 - - - 426.4086 - 2.517 0.57 - 112.4 1 1 0 0.9996 21 0 0 0 1.05E+06 4.71E+07 - - - 6.8311 0.9465 221125_WJC_METTL3_EV_vs_WT_F05.25169.25169.2 2.45 18-Apr K.FAAQELIEVK[136.11].R "sp|Q86U44|MTA70_HUMAN,tr|F5H6D8|F5H6D8_HUMAN,tr|H0YFV6|H0YFV6_HUMAN,tr|B4DTN4|B4DTN4_HUMAN" 4 1154.6427 0.4 74388 25169 2 1154.641955 578.3286 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 4.53 3991.7 - 70700 - - - -0.6236 - 0.774 0.166 - 40.8 1 2 0 -0.0007 10 0 0 0 1.14E+06 2.88E+06 - - - -0.4482 1 221125_WJC_METTL3_EV_vs_WT_F05.25175.25175.4 8.46E-15 17/150 K.SISHYHETLGEALQGVELEFSGLDIK.F "sp|Q9HD45|TM9S3_HUMAN,tr|Q5TB53|Q5TB53_HUMAN" 2 2871.4291 1.49 74392 25175 4 2871.429009 718.8645 Transmembrane 9 superfamily member 3 OS=Homo sapiens OX=9606 GN=TM9SF3 PE=1 SV=2 4.56 3992.5 - 225929 - - - -0.0157 - 3.936 0.627 - 136.8 1 2 0 0 26 0 0 0 7.75E+05 5.21E+05 - - - 5.1156 1 221125_WJC_METTL3_EV_vs_WT_F05.25176.25176.4 8.87E-07 13/150 K.SISHYHETLGEALQGVELEFSGLDIK[136.11].F "sp|Q9HD45|TM9S3_HUMAN,tr|Q5TB53|Q5TB53_HUMAN" 2 2879.4433 1.49 74393 25176 4 2879.437988 720.8681 Transmembrane 9 superfamily member 3 OS=Homo sapiens OX=9606 GN=TM9SF3 PE=1 SV=2 4.56 3992.7 - 157570 - - - -1.8288 - 2.953 0.583 - 88.3 1 2 0 -0.0053 26 0 0 0 7.75E+05 5.21E+05 - - - 4.6405 0.9999 221125_WJC_METTL3_EV_vs_WT_F05.25177.25177.4 0.104 12/120 R.KFDVNTSAVQVLIEHIGNLDR.A "sp|Q00610|CLH1_HUMAN,tr|A0A087WVQ6|A0A087WVQ6_HUMAN" 2 2367.2547 0.91 74394 25177 4 2367.253729 592.8209 Clathrin heavy chain 1 OS=Homo sapiens OX=9606 GN=CLTC PE=1 SV=5 5.38 3992.8 - 161778 - - - -0.3929 - 2.657 0.448 - 99.5 1 2 0 -0.0009 21 0 0 0 6.96E+05 7.65E+05 - - - 3.4482 0.8289 221125_WJC_METTL3_EV_vs_WT_F05.25182.25182.3 0.000602 Sep-80 K.RR[166.11]AEQDSTTVAAFASSLVSGL.N "sp|Q86U44|MTA70_HUMAN,tr|F5H6D8|F5H6D8_HUMAN,tr|H0YFV6|H0YFV6_HUMAN,tr|B4DTN4|B4DTN4_HUMAN" 4 2175.1159 0.02 74397 25182 3 2175.117604 726.0459 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 6.07 3993.5 - 117394 - - - 0.7696 - 1.756 0.364 - 82.2 1 1 1 0.0017 21 0 0 0 1.61E+04 7.48E+05 - - - 3.9476 0.9999 221125_WJC_METTL3_EV_vs_WT_F05.25183.25183.4 0.0144 10/120 R.K[136.11]FDVNTSAVQVLIEHIGNLDR[166.11].A "sp|Q00610|CLH1_HUMAN,tr|A0A087WVQ6|A0A087WVQ6_HUMAN" 2 2385.2771 0.9 74398 25183 4 2385.278819 597.3266 Clathrin heavy chain 1 OS=Homo sapiens OX=9606 GN=CLTC PE=1 SV=5 5.38 3993.6 - 99282.6 - - - 0.7085 - 2.34 0.43 - 59.8 1 2 0 0.0017 21 0 0 0 6.96E+05 7.72E+05 - - - 3.2493 0.9994 221125_WJC_METTL3_EV_vs_WT_F05.25185.25185.2 0.00113 30-Jul K.AAGVNVEPFWPGLFAK.A sp|P05386|RLA1_HUMAN 1 1701.8879 1.5 74400 25185 2 1701.888237 851.9512 60S acidic ribosomal protein P1 OS=Homo sapiens OX=9606 GN=RPLP1 PE=1 SV=1 6.05 3993.9 - 43067.1 - - - 0.2109 - 1.345 0.426 - 109.9 1 2 0 0.0004 16 0 0 0 8.60E+05 5.72E+05 - - - 2.916 0.9985 221125_WJC_METTL3_EV_vs_WT_F05.25190.25190.3 9.40E-08 14/80 R.R[166.11]AEQDSTTVAAFASSLVSGLN.S "sp|Q86U44|MTA70_HUMAN,tr|F5H6D8|F5H6D8_HUMAN,tr|H0YFV6|H0YFV6_HUMAN,tr|B4DTN4|B4DTN4_HUMAN" 4 2133.0577 0.04 74403 25190 3 2133.057189 712.0265 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 4.37 3994.6 - 204501 - - - -0.2616 - 2.843 0.59 - 219.3 1 1 0 -0.0006 21 0 0 0 6.95E+04 1.88E+06 - - - 7.6228 0.9958 221125_WJC_METTL3_EV_vs_WT_F05.25193.25193.2 0.137 30-May K.AAGVNVEPFWPGLFAK[136.11].A sp|P05386|RLA1_HUMAN 1 1709.9021 1.5 74406 25193 2 1709.902663 855.9583 60S acidic ribosomal protein P1 OS=Homo sapiens OX=9606 GN=RPLP1 PE=1 SV=1 6.05 3995 - 46267.1 - - - 0.3421 - 1.024 0.293 - 55.8 1 2 0 0.0006 16 0 0 0 8.60E+05 5.72E+05 - - - 1.2632 0.9999 221125_WJC_METTL3_EV_vs_WT_F05.25199.25199.4 4.59E-09 13/150 R.DFEGAVDLLDKLNHYLEDKPSPPPVK.E sp|Q8IYI6|EXOC8_HUMAN 1 2935.4967 2.25 74410 25199 4 2935.497497 734.8815 Exocyst complex component 8 OS=Homo sapiens OX=9606 GN=EXOC8 PE=1 SV=2 4.52 3995.8 - 163724 - - - 0.2579 - 3.159 0.604 - 39.1 1 2 1 0.0008 26 0 0 0 9.68E+05 4.31E+05 - - - 4.8458 1 221125_WJC_METTL3_EV_vs_WT_F05.25203.25203.3 1.19E-08 Nov-84 R.K[136.11]PLVIIAEDVDGEALSTLVLNR[166.11].L "sp|P10809|CH60_HUMAN,tr|A0A7I2V2X6|A0A7I2V2X6_HUMAN,tr|A0A7I2YQK6|A0A7I2YQK6_HUMAN,tr|A0A7I2V599|A0A7I2V599_HUMAN,tr|A0A7I2YQ71|A0A7I2YQ71_HUMAN,tr|A0A7I2V5M1|A0A7I2V5M1_HUMAN,tr|A0A7I2V5K3|A0A7I2V5K3_HUMAN" 7 2382.3489 1.12 74412 25203 3 2382.347238 795.1236 "60 kDa heat shock protein, mitochondrial OS=Homo sapiens OX=9606 GN=HSPD1 PE=1 SV=2" 4.32 3996.4 - 111480 - - - -0.6964 - 2.576 0.613 - 125.5 1 2 0 -0.0017 22 0 0 0 2.59E+06 2.30E+06 - - - 7.6173 1 221125_WJC_METTL3_EV_vs_WT_F05.25205.25205.3 9.28E-08 Dec-72 K.NVVHQLSVTLEDLYNGATR[166.11].K sp|P31689|DNJA1_HUMAN 1 2138.0996 0.65 74414 25205 3 2138.100107 713.7071 DnaJ homolog subfamily A member 1 OS=Homo sapiens OX=9606 GN=DNAJA1 PE=1 SV=2 5.32 3996.7 - 111189 - - - 0.2596 - 2.648 0.576 - 166.3 1 2 0 0.0006 19 0 0 0 3.90E+05 5.98E+05 - - - 7.3541 0.9997 221125_WJC_METTL3_EV_vs_WT_F05.25211.25211.3 0.00611 Jun-64 K.ATENDIYNFFSPLNPVR[166.11].V "sp|P52597|HNRPF_HUMAN,sp|P31943|HNRH1_HUMAN,tr|H0YBD7|H0YBD7_HUMAN,tr|H0YB39|H0YB39_HUMAN,tr|H0YBG7|H0YBG7_HUMAN,tr|E9PCY7|E9PCY7_HUMAN,tr|G8JLB6|G8JLB6_HUMAN" 7 2005.9773 1.84 74418 25211 3 2005.977537 669.6664 Heterogeneous nuclear ribonucleoprotein F OS=Homo sapiens OX=9606 GN=HNRNPF PE=1 SV=3 4.37 3997.5 - 56673.5 - - - 0.1127 - 1.446 0.416 - 50.3 1 2 0 0.0002 17 0 0 0 1.02E+06 5.56E+05 - - - 4.1096 0.9912 221125_WJC_METTL3_EV_vs_WT_F05.25213.25213.3 5.72E-06 8/124 K.EQVDEWTVETVEVVNSLQQQPQAASPSVPEPH.S "sp|Q14444|CAPR1_HUMAN,tr|G3V153|G3V153_HUMAN" 2 3556.6958 - 74420 25213 3 3556.69682 1186.5725 Caprin-1 OS=Homo sapiens OX=9606 GN=CAPRIN1 PE=1 SV=2 3.83 3997.8 - 88939.5 - - - 0.2904 - 1.492 0.529 - 36.6 1 1 0 0.001 32 0 0 0 - - - - - 5.3581 0.9998 221125_WJC_METTL3_EV_vs_WT_F05.25214.25214.3 0.000571 Jun-64 K.ATENDIYNFFSPLNPVR.V "sp|P52597|HNRPF_HUMAN,sp|P31943|HNRH1_HUMAN,tr|H0YBD7|H0YBD7_HUMAN,tr|H0YB39|H0YB39_HUMAN,tr|H0YBG7|H0YBG7_HUMAN,tr|E9PCY7|E9PCY7_HUMAN,tr|G8JLB6|G8JLB6_HUMAN" 7 1995.969 1.8 74421 25214 3 1995.969463 666.3303 Heterogeneous nuclear ribonucleoprotein F OS=Homo sapiens OX=9606 GN=HNRNPF PE=1 SV=3 4.37 3997.9 - 85790.4 - - - 0.2114 - 1.554 0.447 - 45.7 1 2 0 0.0004 17 0 0 0 1.00E+06 5.56E+05 - - - 4.6372 1 221125_WJC_METTL3_EV_vs_WT_F05.25217.25217.3 7.96E-10 17/84 R.KPLVIIAEDVDGEALSTLVLNR.L "sp|P10809|CH60_HUMAN,tr|A0A7I2V2X6|A0A7I2V2X6_HUMAN,tr|A0A7I2YQK6|A0A7I2YQK6_HUMAN,tr|A0A7I2V599|A0A7I2V599_HUMAN,tr|A0A7I2YQ71|A0A7I2YQ71_HUMAN,tr|A0A7I2V5M1|A0A7I2V5M1_HUMAN,tr|A0A7I2V5K3|A0A7I2V5K3_HUMAN" 7 2364.3264 1.12 74422 25217 3 2364.331765 789.1161 "60 kDa heat shock protein, mitochondrial OS=Homo sapiens OX=9606 GN=HSPD1 PE=1 SV=2" 4.32 3998.3 - 108398 - - - 2.2577 - 3.286 0.643 - 327.8 1 2 0 0.0053 22 0 0 0 2.59E+06 2.30E+06 - - - 8.5278 0.9307 221125_WJC_METTL3_EV_vs_WT_F05.25226.25226.3 1.82E-07 Nov-84 R.R[166.11]AEQDSTTVAAFASSLVSGLNS.S "sp|Q86U44|MTA70_HUMAN,tr|F5H6D8|F5H6D8_HUMAN,tr|H0YFV6|H0YFV6_HUMAN,tr|B4DTN4|B4DTN4_HUMAN" 4 2220.0898 0.45 74427 25226 3 2220.102898 741.0372 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 4.37 3999.6 - 202859 - - - 5.911 - 2.669 0.538 - 101.4 1 1 0 0.0131 22 0 0 0 5.81E+05 1.28E+06 - - - 6.862 1 221125_WJC_METTL3_EV_vs_WT_F05.25228.25228.3 4.52E-08 7/104 K.EIAEAYLGYPVTNAVITVPAYFNDSQR[166.11].Q "sp|P0DMV8|HS71A_HUMAN,sp|P0DMV9|HS71B_HUMAN,tr|A0A0G2JIW1|A0A0G2JIW1_HUMAN" 3 3010.4952 0.03 74428 25228 3 3010.494184 1004.5057 Heat shock 70 kDa protein 1A OS=Homo sapiens OX=9606 GN=HSPA1A PE=1 SV=1 4.14 3999.9 - 65623.3 - - - -0.3285 - 2.303 0.613 - 20.8 1 2 0 -0.001 27 0 0 0 3.96E+04 1.48E+06 - - - 7.2933 1 221125_WJC_METTL3_EV_vs_WT_F05.25245.25245.4 1.61E-07 12/156 R.DLIDDATNLVQLYHVLHPDGQSAQGAK[136.11].D "sp|P82650|RT22_HUMAN,tr|G5E9W7|G5E9W7_HUMAN,tr|A0A7P0MKV3|A0A7P0MKV3_HUMAN" 3 2925.4712 1.6 74441 25245 4 2925.472855 732.3751 "28S ribosomal protein S22, mitochondrial OS=Homo sapiens OX=9606 GN=MRPS22 PE=1 SV=1" 4.54 4002.2 - 121842 - - - 0.5657 - 2.315 0.548 - 41.7 1 2 0 0.0017 27 0 0 0 2.72E+06 1.70E+06 - - - 4.258 1 221125_WJC_METTL3_EV_vs_WT_F05.25246.25246.4 3.15E-11 16/156 R.DLIDDATNLVQLYHVLHPDGQSAQGAK.D "sp|P82650|RT22_HUMAN,tr|G5E9W7|G5E9W7_HUMAN,tr|A0A7P0MKV3|A0A7P0MKV3_HUMAN" 3 2917.457 1.6 74442 25246 4 2917.457599 730.3715 "28S ribosomal protein S22, mitochondrial OS=Homo sapiens OX=9606 GN=MRPS22 PE=1 SV=1" 4.54 4002.4 - 163182 - - - 0.2053 - 3.335 0.584 - 75.1 1 2 0 0.0006 27 0 0 0 2.72E+06 1.70E+06 - - - 4.6858 0.9977 221125_WJC_METTL3_EV_vs_WT_F05.25248.25248.4 0.00133 9/138 R.VHTVEDYQAIVDAEWNILYDK[136.11]LEK[136.11].L sp|Q99832|TCPH_HUMAN 1 2906.4673 0.06 74444 25248 4 2906.462156 727.6241 T-complex protein 1 subunit eta OS=Homo sapiens OX=9606 GN=CCT7 PE=1 SV=2 4.29 4002.6 - 71186.7 - - - -1.7664 - 2.117 0.337 - 43 1 2 1 -0.0051 24 0 0 0 5.56E+04 8.86E+05 - - - 2.3986 0.9999 221125_WJC_METTL3_EV_vs_WT_F05.25254.25254.3 2.04E-06 Aug-88 K.SINPDEAVAYGAAVQAAILSGDK[136.11].S "sp|P11142|HSP7C_HUMAN,tr|E9PNE6|E9PNE6_HUMAN,tr|A8K7Q2|A8K7Q2_HUMAN,tr|E9PKE3|E9PKE3_HUMAN" 4 2267.1525 0.16 74448 25254 3 2267.149559 756.7248 Heat shock cognate 71 kDa protein OS=Homo sapiens OX=9606 GN=HSPA8 PE=1 SV=1 4.03 4003.4 - 87253.8 - - - -1.2937 - 1.659 0.55 - 47.7 1 2 0 -0.0029 23 0 0 0 8.83E+04 5.52E+05 - - - 5.8587 1 221125_WJC_METTL3_EV_vs_WT_F05.25269.25269.2 1.04E-16 22/54 R.AEQDSTTVAAFASSLVSGLNSSASEPAK[136.11].E "sp|Q86U44|MTA70_HUMAN,tr|F5H6D8|F5H6D8_HUMAN,tr|H0YFV6|H0YFV6_HUMAN,tr|B4DTN4|B4DTN4_HUMAN" 4 2732.3232 0.001 74457 25269 2 2733.310434 1367.1689 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 4.14 4005.5 - 2.12E+06 - - - 361.3174 - 4.527 0.756 - 891.7 1 2 0 0.9872 28 0 0 0 0.00E+00 1.61E+07 - - - 8.0274 0.994 221125_WJC_METTL3_EV_vs_WT_F05.25270.25270.4 1.42E-09 23/162 R.AEQDSTTVAAFASSLVSGLNSSASEPAK[136.11].E "sp|Q86U44|MTA70_HUMAN,tr|F5H6D8|F5H6D8_HUMAN,tr|H0YFV6|H0YFV6_HUMAN,tr|B4DTN4|B4DTN4_HUMAN" 4 2732.3232 0.01 74458 25270 4 2733.313311 684.0881 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 4.14 4005.6 - 948047 - - - 362.3704 - 4.534 0.605 - 290.5 1 2 0 0.9901 28 0 0 0 1.61E+05 1.34E+07 - - - 4.687 1 221125_WJC_METTL3_EV_vs_WT_F05.25281.25281.4 1.83E-13 17/150 R.DLDELSRYPEDKITPENLPQILLQLK.R "sp|P43243|MATR3_HUMAN,tr|A8MXP9|A8MXP9_HUMAN,tr|D6R991|D6R991_HUMAN,tr|A0A0R4J2E8|A0A0R4J2E8_HUMAN,tr|D6REM6|D6REM6_HUMAN" 5 3079.6441 2.01 74462 25281 4 3079.631544 770.9183 Matrin-3 OS=Homo sapiens OX=9606 GN=MATR3 PE=1 SV=2 4.3 4007.1 - 226878 - - - -4.0875 - 3.42 0.653 - 155 1 2 2 -0.0126 26 0 0 0 7.17E+05 3.56E+05 - - - 5.2941 0.9552 221125_WJC_METTL3_EV_vs_WT_F05.26016.26016.2 3.2 12-May K.EQSIVEK[136.11].F "sp|Q86U44|MTA70_HUMAN,tr|H0YFV6|H0YFV6_HUMAN" 2 839.448 0.01 74550 26016 2 839.447996 420.7313 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 4.53 4136.5 - 495358 - - - -0.0024 - 1.206 0.018 - 167.3 2 2 0 0 7 0 0 0 9.04E+03 1.02E+06 - - - -0.367 0.975 221125_WJC_METTL3_EV_vs_WT_F06.02391.02391.2 0.00193 14-Jul K.VTGDSQPK[136.11].E sp|O76094|SRP72_HUMAN 1 838.4276 0.44 74623 2391 2 838.422979 420.2211 Signal recognition particle subunit SRP72 OS=Homo sapiens OX=9606 GN=SRP72 PE=1 SV=3 5.81 1179.2 - 1.15E+06 - - - -5.5079 - 1.461 0.305 - 147.5 1 2 0 -0.0046 8 0 0 0 1.15E+07 2.64E+07 - - - 2.4357 0.9857 221125_WJC_METTL3_EV_vs_WT_F06.02392.02392.2 0.06 14-Jul R.GVNASAQK[136.11].F "sp|Q01082|SPTB2_HUMAN,tr|A0A087WUZ3|A0A087WUZ3_HUMAN,tr|F8W6C1|F8W6C1_HUMAN" 3 781.4174 0.86 74624 2392 2 781.413814 391.716 "Spectrin beta chain, non-erythrocytic 1 OS=Homo sapiens OX=9606 GN=SPTBN1 PE=1 SV=2" 8.75 1179.3 - 769783 - - - -4.5456 - 1.535 0.271 - 130.1 1 2 0 -0.0036 8 0 0 0 2.11E+07 2.46E+07 - - - 2.3339 0.787 221125_WJC_METTL3_EV_vs_WT_F06.02396.02396.2 0.535 12-Jun R.GSC[160.03]TLGR[166.11].E sp|Q68DU8|KCD16_HUMAN 1 759.3573 0.001 74628 2396 2 759.353578 380.6859 BTB\POZ domain-containing protein KCTD16 OS=Homo sapiens OX=9606 GN=KCTD16 PE=1 SV=1 8.25 1179.8 - 573198 - - - -4.8923 - 1.046 0.158 - 159.5 1 2 0 -0.0037 7 0 0 0 0.00E+00 1.08E+08 - - - 0.3493 0.8656 221125_WJC_METTL3_EV_vs_WT_F06.02401.02401.2 0.00727 18-Jul Y.PDGGDQETAK.T "sp|Q9NYF8|BCLF1_HUMAN,tr|H0YF00|H0YF00_HUMAN,tr|E9PKI6|E9PKI6_HUMAN,tr|A0A1W2PQ43|A0A1W2PQ43_HUMAN,tr|E9PK91|E9PK91_HUMAN,tr|E9PJA7|E9PJA7_HUMAN,tr|E9PK09|E9PK09_HUMAN,tr|E9PQN2|E9PQN2_HUMAN" 8 1016.4411 2.68 74631 2401 2 1016.436935 509.2278 Bcl-2-associated transcription factor 1 OS=Homo sapiens OX=9606 GN=BCLAF1 PE=1 SV=2 4.03 1180.5 - 402829 - - - -4.0661 - 1.687 0.437 - 236.8 1 1 0 -0.0041 10 0 0 0 2.38E+07 8.88E+06 - - - 3.7271 0.9833 221125_WJC_METTL3_EV_vs_WT_F06.02426.02426.2 0.128 16-Jul K.AGAVASQTK.A "sp|Q13428|TCOF_HUMAN,tr|E7ETY2|E7ETY2_HUMAN,tr|H0Y8Y7|H0Y8Y7_HUMAN,tr|A0A3B3IS06|A0A3B3IS06_HUMAN,tr|A0A6I8PRA0|A0A6I8PRA0_HUMAN" 5 831.445 1.07 74638 2426 2 831.441237 416.7298 Treacle protein OS=Homo sapiens OX=9606 GN=TCOF1 PE=1 SV=3 8.8 1184 - 807053 - - - -4.5631 - 1.767 0.206 - 170.2 1 2 0 -0.0038 9 0 0 0 8.64E+07 8.05E+07 - - - 2.2083 0.8865 221125_WJC_METTL3_EV_vs_WT_F06.02430.02430.2 0.0836 12-Aug K.VGHVTER[166.11].T "sp|Q14498|RBM39_HUMAN,sp|Q86U06|RBM23_HUMAN,tr|A0A0U1RQW2|A0A0U1RQW2_HUMAN,tr|H0Y4X3|H0Y4X3_HUMAN,tr|H0YJJ3|H0YJJ3_HUMAN,tr|G3XAP0|G3XAP0_HUMAN,tr|A0A0U1RQH7|A0A0U1RQH7_HUMAN,tr|G3V5Z6|G3V5Z6_HUMAN,tr|G3XAC6|G3XAC6_HUMAN" 9 806.4274 1.4 74639 2430 2 806.423807 404.221 RNA-binding protein 39 OS=Homo sapiens OX=9606 GN=RBM39 PE=1 SV=2 6.72 1184.6 - 3.63E+06 - - - -4.4815 - 1.274 0.114 - 319.4 1 2 0 -0.0036 7 0 0 0 3.06E+08 2.18E+08 - - - 0.6492 0.9756 221125_WJC_METTL3_EV_vs_WT_F06.02432.02432.2 0.00672 16-Oct K.AGAVASQTK[136.11].A "sp|Q13428|TCOF_HUMAN,tr|E7ETY2|E7ETY2_HUMAN,tr|H0Y8Y7|H0Y8Y7_HUMAN,tr|A0A3B3IS06|A0A3B3IS06_HUMAN,tr|A0A6I8PRA0|A0A6I8PRA0_HUMAN" 5 839.4592 1.07 74641 2432 2 839.455362 420.7369 Treacle protein OS=Homo sapiens OX=9606 GN=TCOF1 PE=1 SV=3 8.8 1184.7 - 1.26E+06 - - - -4.6089 - 1.983 0.121 - 432.8 1 2 0 -0.0039 9 0 0 0 8.64E+07 8.05E+07 - - - 1.9141 0.9903 221125_WJC_METTL3_EV_vs_WT_F06.02438.02438.2 0.0766 12-Jul K.VGDQAQR[166.11].R sp|P61158|ARP3_HUMAN 1 782.391 1.74 74643 2438 2 782.388476 392.2028 Actin-related protein 3 OS=Homo sapiens OX=9606 GN=ACTR3 PE=1 SV=3 5.81 1185.6 - 659915 - - - -3.2707 - 1.332 0.261 - 126.3 1 2 0 -0.0026 7 0 0 0 5.39E+07 3.09E+07 - - - 1.8763 0.9933 221125_WJC_METTL3_EV_vs_WT_F06.02445.02445.2 0.0286 18-Sep K.AGAHLQGGAK.R "sp|P04406|G3P_HUMAN,tr|E7EUT5|E7EUT5_HUMAN" 2 908.4828 0.46 74648 2445 2 908.480033 455.2487 Glyceraldehyde-3-phosphate dehydrogenase OS=Homo sapiens OX=9606 GN=GAPDH PE=1 SV=3 8.8 1186.5 - 242896 - - - -3.0611 - 1.605 0.23 - 219.6 1 2 0 -0.0028 10 0 0 0 1.92E+07 4.20E+07 - - - 2.0595 0.9951 221125_WJC_METTL3_EV_vs_WT_F06.02456.02456.2 0.000767 18-Nov K.AGAHLQGGAK[136.11].R "sp|P04406|G3P_HUMAN,tr|E7EUT5|E7EUT5_HUMAN" 2 916.497 0.46 74653 2456 2 916.492492 459.2558 Glyceraldehyde-3-phosphate dehydrogenase OS=Homo sapiens OX=9606 GN=GAPDH PE=1 SV=3 8.8 1187.9 - 706916 - - - -4.934 - 1.593 0.455 - 282.6 1 2 0 -0.0045 10 0 0 0 2.04E+07 4.49E+07 - - - 3.6999 0.9237 221125_WJC_METTL3_EV_vs_WT_F06.02469.02469.2 0.0119 12-Jul R.QAQVAEK[136.11].L "sp|Q8N6H7|ARFG2_HUMAN,tr|E9PIY6|E9PIY6_HUMAN,tr|E9PQP3|E9PQP3_HUMAN,tr|G5E9L0|G5E9L0_HUMAN,tr|A0A0D9SF70|A0A0D9SF70_HUMAN" 5 780.4221 1.41 74660 2469 2 780.417277 391.2183 ADP-ribosylation factor GTPase-activating protein 2 OS=Homo sapiens OX=9606 GN=ARFGAP2 PE=1 SV=1 6 1189.4 - 806619 - - - -6.2031 - 1.352 0.252 - 255.5 1 2 0 -0.0048 7 0 0 0 1.57E+08 1.12E+08 - - - 1.8563 0.9917 221125_WJC_METTL3_EV_vs_WT_F06.02483.02483.2 0.00742 14-Aug K.VEQDTETK[136.11].L sp|Q9NZI8|IF2B1_HUMAN 1 956.4542 1.65 74666 2483 2 956.450806 479.2344 Insulin-like growth factor 2 mRNA-binding protein 1 OS=Homo sapiens OX=9606 GN=IGF2BP1 PE=1 SV=2 4.14 1191.3 - 512997 - - - -3.5548 - 1.446 0.275 - 213.1 1 2 0 -0.0034 8 0 0 0 9.53E+07 5.76E+07 - - - 2.1834 0.8488 221125_WJC_METTL3_EV_vs_WT_F06.02497.02497.2 0.000285 16-Sep W.VSSAAQTEK[136.11].G "sp|Q92947|GCDH_HUMAN,tr|K7ERX1|K7ERX1_HUMAN,tr|K7ES74|K7ES74_HUMAN,tr|K7EKH1|K7EKH1_HUMAN,tr|K7ER63|K7ER63_HUMAN" 5 927.4753 1.18 74670 2497 2 927.470837 464.7449 "Glutaryl-CoA dehydrogenase, mitochondrial OS=Homo sapiens OX=9606 GN=GCDH PE=1 SV=1" 5.97 1193.2 - 483924 - - - -4.785 - 2.038 0.424 - 217.5 1 1 0 -0.0044 9 0 0 0 1.90E+08 1.61E+08 - - - 4.231 0.8877 221125_WJC_METTL3_EV_vs_WT_F06.02501.02501.2 0.00809 16-Aug W.VSSAAQTEK.G "sp|Q92947|GCDH_HUMAN,tr|K7ERX1|K7ERX1_HUMAN,tr|K7ES74|K7ES74_HUMAN,tr|K7EKH1|K7EKH1_HUMAN,tr|K7ER63|K7ER63_HUMAN" 5 919.4611 1.18 74672 2501 2 919.457616 460.7378 "Glutaryl-CoA dehydrogenase, mitochondrial OS=Homo sapiens OX=9606 GN=GCDH PE=1 SV=1" 5.97 1193.7 - 1.51E+06 - - - -3.762 - 1.942 0.372 - 168.2 1 1 0 -0.0035 9 0 0 0 1.90E+08 1.61E+08 - - - 3.7077 0.9733 221125_WJC_METTL3_EV_vs_WT_F06.02541.02541.2 0.109 14-Jul K.EASGTDVK[136.11].Q sp|Q8N0X7|SPART_HUMAN 1 813.396 1.34 74685 2541 2 813.391185 407.7053 Spartin OS=Homo sapiens OX=9606 GN=SPART PE=1 SV=1 4.37 1198.8 - 2.43E+06 - - - -5.8729 - 1.721 0.261 - 269.7 1 2 0 -0.0048 8 0 0 0 1.29E+08 9.68E+07 - - - 2.6046 0.839 221125_WJC_METTL3_EV_vs_WT_F06.02576.02576.2 1.36 12-Aug K.VAEQQER[166.11].E sp|Q86U86|PB1_HUMAN 1 868.4278 0.2 74696 2576 2 868.422445 435.2212 Protein polybromo-1 OS=Homo sapiens OX=9606 GN=PBRM1 PE=1 SV=1 4.53 1203.5 - 1.27E+06 - - - -6.1836 - 1.495 0.121 - 240.7 1 2 0 -0.0054 7 0 0 0 1.89E+07 9.40E+07 - - - 1.2072 0.8451 221125_WJC_METTL3_EV_vs_WT_F06.02596.02596.2 0.197 12-Aug K.QLDQGNK[136.11].D sp|Q8N0X7|SPART_HUMAN 1 809.4123 1.17 74705 2596 2 809.407993 405.7134 Spartin OS=Homo sapiens OX=9606 GN=SPART PE=1 SV=1 5.84 1205.9 - 3.13E+06 - - - -5.2977 - 1.163 0.174 - 165.4 1 2 0 -0.0043 7 0 0 0 7.28E+07 6.22E+07 - - - 0.8033 0.9462 221125_WJC_METTL3_EV_vs_WT_F06.02598.02598.2 0.0368 12-Aug K.QLDQGNK.D sp|Q8N0X7|SPART_HUMAN 1 801.3981 1.18 74707 2598 2 801.393157 401.7063 Spartin OS=Homo sapiens OX=9606 GN=SPART PE=1 SV=1 5.84 1206 - 2.71E+06 - - - -6.1443 - 1.3 0.306 - 261.7 1 2 0 -0.0049 7 0 0 0 7.30E+07 6.19E+07 - - - 2.1309 0.9209 221125_WJC_METTL3_EV_vs_WT_F06.02599.02599.2 0.0804 12-Jul K.NQVTATK[136.11].A "sp|P09622|DLDH_HUMAN,tr|E9PEX6|E9PEX6_HUMAN" 2 768.4221 1.52 74708 2599 2 768.418026 385.2183 "Dihydrolipoyl dehydrogenase, mitochondrial OS=Homo sapiens OX=9606 GN=DLD PE=1 SV=2" 8.75 1206.1 - 1.97E+06 - - - -5.3252 - 1.401 0.169 - 293.8 1 2 0 -0.0041 7 0 0 0 1.15E+08 7.55E+07 - - - 1.3563 0.9765 221125_WJC_METTL3_EV_vs_WT_F06.02609.02609.2 0.00021 20-Sep R.SGATAGAAGGR.G sp|P50991|TCPD_HUMAN 1 874.4257 1.86 74714 2609 2 874.420157 438.2201 T-complex protein 1 subunit delta OS=Homo sapiens OX=9606 GN=CCT4 PE=1 SV=4 9.47 1207.3 - 262553 - - - -6.331 - 1.835 0.319 - 206.7 1 2 0 -0.0055 11 0 0 0 2.16E+07 1.17E+07 - - - 3.0376 0.9575 221125_WJC_METTL3_EV_vs_WT_F06.02618.02618.2 0.112 12-Jul K.NQVTATK.A "sp|P09622|DLDH_HUMAN,tr|E9PEX6|E9PEX6_HUMAN" 2 760.4079 1.52 74718 2618 2 760.403445 381.2112 "Dihydrolipoyl dehydrogenase, mitochondrial OS=Homo sapiens OX=9606 GN=DLD PE=1 SV=2" 8.75 1208.4 - 6.97E+06 - - - -5.8824 - 1.521 0.246 - 351.8 1 2 0 -0.0045 7 0 0 0 1.15E+08 7.55E+07 - - - 2.1853 0.9346 221125_WJC_METTL3_EV_vs_WT_F06.02638.02638.2 0.188 14-Aug K.TTPASGER.G sp|P12270|TPR_HUMAN 1 817.393 0.99 74723 2638 2 817.388721 409.7038 Nucleoprotein TPR OS=Homo sapiens OX=9606 GN=TPR PE=1 SV=3 5.66 1211.2 - 5.64E+06 - - - -5.23 - 1.583 0.14 - 369.8 1 2 0 -0.0043 8 0 0 0 1.48E+08 1.50E+08 - - - 1.459 0.9051 221125_WJC_METTL3_EV_vs_WT_F06.02656.02656.2 1.23 12-Jun K.ESESVDK.V "sp|Q14103|HNRPD_HUMAN,tr|H0Y8G5|H0Y8G5_HUMAN,tr|D6RF44|D6RF44_HUMAN,tr|D6RBQ9|D6RBQ9_HUMAN,tr|D6RAF8|D6RAF8_HUMAN,tr|H0YA96|H0YA96_HUMAN" 6 792.3501 1.44 74730 2656 2 792.345888 397.1823 Heterogeneous nuclear ribonucleoprotein D0 OS=Homo sapiens OX=9606 GN=HNRNPD PE=1 SV=1 4.14 1213.4 - 1.58E+07 - - - -5.3512 - 1.382 0.157 - 138.7 1 2 0 -0.0042 7 0 0 0 3.20E+08 2.23E+08 - - - 1.2244 0.9985 221125_WJC_METTL3_EV_vs_WT_F06.02675.02675.2 0.000443 16-Oct R.AAATQPDAK[136.11].D sp|Q7KZF4|SND1_HUMAN 1 879.4541 0.83 74740 2675 2 879.450505 440.7343 Staphylococcal nuclease domain-containing protein 1 OS=Homo sapiens OX=9606 GN=SND1 PE=1 SV=1 5.88 1215.7 - 1.99E+06 - - - -4.1401 - 1.892 0.489 - 446 1 2 0 -0.0036 9 0 0 0 3.76E+07 4.53E+07 - - - 4.4963 0.9828 221125_WJC_METTL3_EV_vs_WT_F06.02687.02687.2 0.0961 14-Jul K.VVSSC[160.03]QEK.R "sp|P11717|MPRI_HUMAN,tr|A0A7I2V381|A0A7I2V381_HUMAN" 2 935.4382 2.62 74748 2687 2 935.433903 468.7264 Cation-independent mannose-6-phosphate receptor OS=Homo sapiens OX=9606 GN=IGF2R PE=1 SV=3 5.97 1216.9 - 1.05E+06 - - - -4.6278 - 1.467 0.274 - 125.7 1 2 0 -0.0043 8 0 0 0 6.52E+07 2.49E+07 - - - 2.2192 0.9835 221125_WJC_METTL3_EV_vs_WT_F06.02700.02700.2 0.0135 14-Aug K.EAEQEAAR[166.11].R sp|Q15149|PLEC_HUMAN 1 912.4176 1.97 74756 2700 2 912.413369 457.2161 Plectin OS=Homo sapiens OX=9606 GN=PLEC PE=1 SV=3 4.25 1218.2 - 688321 - - - -4.6854 - 1.677 0.229 - 331.6 1 2 0 -0.0043 8 0 0 0 4.24E+07 2.16E+07 - - - 2.2903 0.9982 221125_WJC_METTL3_EV_vs_WT_F06.02701.02701.2 0.0209 16-Sep K.VQAAQSEAK.V "sp|Q16891|MIC60_HUMAN,tr|B9A067|B9A067_HUMAN,tr|C9J406|C9J406_HUMAN,tr|H7C463|H7C463_HUMAN" 4 930.4771 1.43 74757 2701 2 930.473319 466.2458 MICOS complex subunit MIC60 OS=Homo sapiens OX=9606 GN=IMMT PE=1 SV=1 5.97 1218.3 - 950868 - - - -4.0205 - 1.941 0.429 - 244 1 2 0 -0.0037 9 0 0 0 8.02E+08 5.62E+08 - - - 4.1271 0.895 221125_WJC_METTL3_EV_vs_WT_F06.02705.02705.2 0.0907 12-Jun R.VLENHAR.G "sp|O94979|SC31A_HUMAN,tr|H0Y9T9|H0Y9T9_HUMAN,tr|D6RHZ5|D6RHZ5_HUMAN,tr|D6REX3|D6REX3_HUMAN" 4 837.4457 2.16 74759 2705 2 837.441126 419.7301 Protein transport protein Sec31A OS=Homo sapiens OX=9606 GN=SEC31A PE=1 SV=3 6.72 1218.8 - 1.09E+06 - - - -5.4618 - 1.181 0.221 - 128.8 1 2 0 -0.0046 7 0 0 0 2.59E+07 1.20E+07 - - - 1.199 0.9911 221125_WJC_METTL3_EV_vs_WT_F06.02709.02709.2 0.261 14-Aug R.LENGNQAR[166.11].S "sp|P26358|DNMT1_HUMAN,tr|A0A7I2V5D0|A0A7I2V5D0_HUMAN,tr|K7EJL0|K7EJL0_HUMAN,tr|A0A7I2V5F1|A0A7I2V5F1_HUMAN,tr|A0A7I2V5F6|A0A7I2V5F6_HUMAN,tr|A0A7I2V2G5|A0A7I2V2G5_HUMAN,tr|A0A7I2YQA8|A0A7I2YQA8_HUMAN,tr|A0A7I2YQQ0|A0A7I2YQQ0_HUMAN,tr|A0A7I2V490|A0A7I2V490_HUMAN" 9 910.4496 1.59 74763 2709 2 910.445573 456.2321 DNA (cytosine-5)-methyltransferase 1 OS=Homo sapiens OX=9606 GN=DNMT1 PE=1 SV=2 6 1219.1 - 1.16E+06 - - - -4.4374 - 1.675 0.284 - 214 1 2 0 -0.004 8 0 0 0 7.69E+07 4.83E+07 - - - 2.693 0.9926 221125_WJC_METTL3_EV_vs_WT_F06.02710.02710.2 0.00696 16-Oct K.LGGNNTSEK.A "sp|Q14527|HLTF_HUMAN,tr|A0A0C4DGA6|A0A0C4DGA6_HUMAN" 2 918.4407 1.43 74764 2710 2 918.435751 460.2276 Helicase-like transcription factor OS=Homo sapiens OX=9606 GN=HLTF PE=1 SV=2 6 1219.3 - 1.03E+06 - - - -5.3602 - 1.918 0.36 - 211 1 2 0 -0.0049 9 0 0 0 3.08E+08 2.15E+08 - - - 3.5826 0.9945 221125_WJC_METTL3_EV_vs_WT_F06.02715.02715.2 0.137 16-Sep K.VQAAQSEAK[136.11].V "sp|Q16891|MIC60_HUMAN,tr|B9A067|B9A067_HUMAN,tr|C9J406|C9J406_HUMAN,tr|H7C463|H7C463_HUMAN" 4 938.4913 1.43 74767 2715 2 938.487084 470.2529 MICOS complex subunit MIC60 OS=Homo sapiens OX=9606 GN=IMMT PE=1 SV=1 5.97 1219.8 - 8.87E+06 - - - -4.4497 - 1.751 0.341 - 244.1 1 2 0 -0.0042 9 0 0 0 8.02E+08 5.62E+08 - - - 3.179 0.9457 221125_WJC_METTL3_EV_vs_WT_F06.02717.02717.2 0.112 14-Jul K.TGVNGDSR[166.11].Y "sp|P16083|NQO2_HUMAN,tr|Q5TD07|Q5TD07_HUMAN" 2 814.3809 1.72 74769 2717 2 814.376922 408.1977 Ribosyldihydronicotinamide dehydrogenase [quinone] OS=Homo sapiens OX=9606 GN=NQO2 PE=1 SV=5 5.5 1219.9 - 3.45E+06 - - - -4.8417 - 1.254 0.227 - 198.9 1 2 0 -0.0039 8 0 0 0 6.96E+07 4.04E+07 - - - 1.399 0.893 221125_WJC_METTL3_EV_vs_WT_F06.02718.02718.2 0.57 14-Jun K.VVSSC[160.03]QEK[136.11].R "sp|P11717|MPRI_HUMAN,tr|A0A7I2V381|A0A7I2V381_HUMAN" 2 943.4524 2.62 74770 2718 2 943.448022 472.7335 Cation-independent mannose-6-phosphate receptor OS=Homo sapiens OX=9606 GN=IGF2R PE=1 SV=3 5.97 1220 - 1.24E+06 - - - -4.6743 - 1.127 0.188 - 83.6 1 2 0 -0.0044 8 0 0 0 6.52E+07 2.49E+07 - - - 0.7888 0.9473 221125_WJC_METTL3_EV_vs_WT_F06.02724.02724.2 1.72 14-Jun R.LENGNQAR.S "sp|P26358|DNMT1_HUMAN,tr|A0A7I2V5D0|A0A7I2V5D0_HUMAN,tr|K7EJL0|K7EJL0_HUMAN,tr|A0A7I2V5F1|A0A7I2V5F1_HUMAN,tr|A0A7I2V5F6|A0A7I2V5F6_HUMAN,tr|A0A7I2V2G5|A0A7I2V2G5_HUMAN,tr|A0A7I2YQA8|A0A7I2YQA8_HUMAN,tr|A0A7I2YQQ0|A0A7I2YQQ0_HUMAN,tr|A0A7I2V490|A0A7I2V490_HUMAN" 9 900.4413 1.63 74773 2724 2 900.437305 451.2279 DNA (cytosine-5)-methyltransferase 1 OS=Homo sapiens OX=9606 GN=DNMT1 PE=1 SV=2 6 1220.7 - 2.59E+06 - - - -4.4845 - 1.402 0.159 - 122.4 1 2 0 -0.004 8 0 0 0 7.85E+07 4.83E+07 - - - 1.2332 0.7893 221125_WJC_METTL3_EV_vs_WT_F06.02732.02732.2 1.21 14-Aug K.AVSEAQEK.L sp|Q16512|PKN1_HUMAN 1 860.424 2.09 74776 2732 2 860.418907 431.2193 Serine\threonine-protein kinase N1 OS=Homo sapiens OX=9606 GN=PKN1 PE=1 SV=2 4.53 1221.8 - 2.20E+06 - - - -5.875 - 1.298 0.135 - 190.3 1 2 0 -0.0051 8 0 0 0 1.10E+08 5.27E+07 - - - 0.8232 0.9464 221125_WJC_METTL3_EV_vs_WT_F06.02755.02755.2 0.154 14-Aug K.VTEGQQER[166.11].L sp|Q13263|TIF1B_HUMAN 1 955.4598 0.78 74788 2755 2 955.45518 478.7372 Transcription intermediary factor 1-beta OS=Homo sapiens OX=9606 GN=TRIM28 PE=1 SV=5 4.53 1224.5 - 968658 - - - -4.8804 - 1.5 0.158 - 202.2 1 2 0 -0.0047 8 0 0 0 7.04E+07 9.04E+07 - - - 1.4294 0.9781 221125_WJC_METTL3_EV_vs_WT_F06.02767.02767.2 0.0713 14-Sep R.IEGDNENK.L "sp|P51114|FXR1_HUMAN,tr|E7EU85|E7EU85_HUMAN,tr|E9PFF5|E9PFF5_HUMAN,tr|B4DXZ6|B4DXZ6_HUMAN" 4 917.409 19.58 74792 2767 2 917.404696 459.7118 Fragile X mental retardation syndrome-related protein 1 OS=Homo sapiens OX=9606 GN=FXR1 PE=1 SV=3 4.14 1226 - 1.47E+06 - - - -4.7351 - 1.236 0.325 - 147.9 1 2 0 -0.0043 8 0 0 0 6.09E+08 3.11E+07 - - - 2.0791 0.9892 221125_WJC_METTL3_EV_vs_WT_F06.02769.02769.2 0.0655 14-Jun K.VTEGQQER.L sp|Q13263|TIF1B_HUMAN 1 945.4516 0.78 74793 2769 2 945.44697 473.7331 Transcription intermediary factor 1-beta OS=Homo sapiens OX=9606 GN=TRIM28 PE=1 SV=5 4.53 1226.2 - 2.86E+06 - - - -4.8686 - 1.611 0.315 - 118.8 1 2 0 -0.0046 8 0 0 0 7.02E+07 9.04E+07 - - - 2.8043 0.995 221125_WJC_METTL3_EV_vs_WT_F06.02773.02773.2 0.0621 14-Jul R.IEGDNENK[136.11].L "sp|P51114|FXR1_HUMAN,tr|E7EU85|E7EU85_HUMAN,tr|E9PFF5|E9PFF5_HUMAN,tr|B4DXZ6|B4DXZ6_HUMAN" 4 925.4232 19.29 74795 2773 2 925.42057 463.7189 Fragile X mental retardation syndrome-related protein 1 OS=Homo sapiens OX=9606 GN=FXR1 PE=1 SV=3 4.14 1226.7 - 1.19E+06 - - - -2.8852 - 1.328 0.312 - 105.7 1 2 0 -0.0027 8 0 0 0 6.00E+08 3.11E+07 - - - 2.2001 0.9957 221125_WJC_METTL3_EV_vs_WT_F06.02792.02792.2 0.000398 22-Oct K.MAAAGGGGGGGR[166.11].Y sp|P14866|HNRPL_HUMAN 1 927.422 1.44 74801 2792 2 927.417001 464.7183 Heterogeneous nuclear ribonucleoprotein L OS=Homo sapiens OX=9606 GN=HNRNPL PE=1 SV=2 9.5 1229.3 - 1.85E+06 - - - -5.4096 - 2.153 0.443 - 324.5 1 2 0 -0.005 12 0 0 0 5.90E+08 4.09E+08 - - - 4.3292 0.8335 221125_WJC_METTL3_EV_vs_WT_F06.02810.02810.2 3.36 14-Jul K.TTTPGETK[136.11].L "sp|Q9NVT9|ARMC1_HUMAN,tr|E5RHK3|E5RHK3_HUMAN,tr|E5RJ86|E5RJ86_HUMAN" 3 841.4273 1.44 74808 2810 2 841.423915 421.7209 Armadillo repeat-containing protein 1 OS=Homo sapiens OX=9606 GN=ARMC1 PE=1 SV=1 5.66 1231.6 - 2.31E+06 - - - -3.979 - 1.234 0.06 - 152.2 1 2 0 -0.0033 8 0 0 0 1.45E+08 1.00E+08 - - - 0.1172 0.993 221125_WJC_METTL3_EV_vs_WT_F06.02821.02821.2 2.64E-05 14-Aug K.TVDGPSGK[136.11].L "sp|P04406|G3P_HUMAN,tr|E7EUT5|E7EUT5_HUMAN" 2 767.3905 0.93 74814 2821 2 767.385969 384.7025 Glyceraldehyde-3-phosphate dehydrogenase OS=Homo sapiens OX=9606 GN=GAPDH PE=1 SV=3 5.5 1232.8 - 7.59E+06 - - - -5.8823 - 1.684 0.474 - 173.7 1 2 0 -0.0045 8 0 0 0 3.76E+10 4.04E+10 - - - 4.1124 0.9426 221125_WJC_METTL3_EV_vs_WT_F06.02822.02822.2 0.378 14-Aug R.AGPLSGK[136.11]K[136.11].F "sp|P17844|DDX5_HUMAN,tr|J3QR02|J3QR02_HUMAN,tr|J3QKN9|J3QKN9_HUMAN,tr|X6RLV5|X6RLV5_HUMAN,tr|A0A7I2V507|A0A7I2V507_HUMAN,tr|J3KTA4|J3KTA4_HUMAN,tr|J3KTQ4|J3KTQ4_HUMAN,tr|A0A7I2V2S0|A0A7I2V2S0_HUMAN,tr|J3QRQ7|J3QRQ7_HUMAN" 9 772.4778 0.22 74815 2822 2 772.474119 387.2462 Probable ATP-dependent RNA helicase DDX5 OS=Homo sapiens OX=9606 GN=DDX5 PE=1 SV=1 10 1232.9 - 5.95E+06 - - - -4.7497 - 1.551 0.128 - 243.1 1 2 0 -0.0037 8 0 0 0 6.33E+07 2.82E+08 - - - 1.309 0.9952 221125_WJC_METTL3_EV_vs_WT_F06.02824.02824.2 0.0207 16-Aug R.VEGQATDEK.K "sp|Q8TAQ2|SMRC2_HUMAN,tr|F8VXC8|F8VXC8_HUMAN" 2 975.4509 5.06 74817 2824 2 975.447107 488.7327 SWI\SNF complex subunit SMARCC2 OS=Homo sapiens OX=9606 GN=SMARCC2 PE=1 SV=1 4.14 1233.1 - 642063 - - - -3.8936 - 1.571 0.346 - 240.8 1 2 0 -0.0038 9 0 0 0 3.95E+07 7.81E+06 - - - 2.9022 0.8089 221125_WJC_METTL3_EV_vs_WT_F06.02847.02847.2 0.256 12-Jun R.QQAEVEK[136.11].Q "sp|O76031|CLPX_HUMAN,tr|H0YM48|H0YM48_HUMAN" 2 838.4276 2.06 74822 2847 2 838.422107 420.2211 "ATP-dependent Clp protease ATP-binding subunit clpX-like, mitochondrial OS=Homo sapiens OX=9606 GN=CLPX PE=1 SV=2" 4.53 1236.4 - 2.63E+06 - - - -6.548 - 1.355 0.167 - 182.4 1 2 0 -0.0055 7 0 0 0 2.95E+08 1.44E+08 - - - 1.2353 0.8991 221125_WJC_METTL3_EV_vs_WT_F06.02859.02859.2 0.0242 14-Aug K.GVSASQDR[166.11].K "sp|Q8IWZ3|ANKH1_HUMAN,tr|A0A0A0MQZ8|A0A0A0MQZ8_HUMAN,tr|H0Y472|H0Y472_HUMAN,tr|H0Y7Y3|H0Y7Y3_HUMAN,tr|H0Y4P6|H0Y4P6_HUMAN,tr|H7C0V5|H7C0V5_HUMAN,tr|H0Y785|H0Y785_HUMAN,tr|H7C2E1|H7C2E1_HUMAN" 8 828.3965 1.11 74825 2859 2 828.390015 415.2055 Ankyrin repeat and KH domain-containing protein 1 OS=Homo sapiens OX=9606 GN=ANKHD1 PE=1 SV=1 5.84 1238.1 - 1.29E+07 - - - -7.8465 - 1.651 0.256 - 185.4 1 2 0 -0.0065 8 0 0 0 1.14E+09 1.04E+09 - - - 2.4419 0.9704 221125_WJC_METTL3_EV_vs_WT_F06.02865.02865.2 0.0752 12-Aug K.KLEDGPK.F "sp|P68104|EF1A1_HUMAN,sp|Q5VTE0|EF1A3_HUMAN,tr|A0A7I2V659|A0A7I2V659_HUMAN,tr|A0A7I2V5N4|A0A7I2V5N4_HUMAN,tr|A0A087WVQ9|A0A087WVQ9_HUMAN,tr|A0A087WV01|A0A087WV01_HUMAN" 6 785.4283 0.38 74827 2865 2 785.423413 393.7214 Elongation factor 1-alpha 1 OS=Homo sapiens OX=9606 GN=EEF1A1 PE=1 SV=1 6.07 1238.9 - 1.36E+07 - - - -6.2463 - 1.667 0.283 - 242.1 1 2 0 -0.0049 7 0 0 0 1.78E+09 4.65E+09 - - - 2.7489 0.9939 221125_WJC_METTL3_EV_vs_WT_F06.02877.02877.2 0.0611 12-Sep K.K[136.11]LEDGPK[136.11].F "sp|P68104|EF1A1_HUMAN,sp|Q5VTE0|EF1A3_HUMAN,tr|A0A7I2V659|A0A7I2V659_HUMAN,tr|A0A7I2V5N4|A0A7I2V5N4_HUMAN,tr|A0A087WVQ9|A0A087WVQ9_HUMAN,tr|A0A087WV01|A0A087WV01_HUMAN" 6 801.4567 0.38 74831 2877 2 801.452108 401.7356 Elongation factor 1-alpha 1 OS=Homo sapiens OX=9606 GN=EEF1A1 PE=1 SV=1 6.07 1240.4 - 5.33E+07 - - - -5.7533 - 1.931 0.414 - 284.7 1 2 0 -0.0046 7 0 0 0 1.78E+09 4.65E+09 - - - 4.1824 0.9904 221125_WJC_METTL3_EV_vs_WT_F06.02886.02886.2 0.00856 14-Jul K.EVAQDC[160.03]TK[136.11].A sp|O94826|TOM70_HUMAN 1 957.4317 1.2 74836 2886 2 957.427247 479.7231 Mitochondrial import receptor subunit TOM70 OS=Homo sapiens OX=9606 GN=TOMM70 PE=1 SV=1 4.37 1241.4 - 411240 - - - -4.6468 - 1.306 0.396 - 236.8 1 2 0 -0.0044 8 0 0 0 1.09E+07 9.07E+06 - - - 2.7696 1 221125_WJC_METTL3_EV_vs_WT_F06.02904.02904.2 1.83E-06 16-Oct K.VVC[160.03]DENGSK.G "sp|Q13310|PABP4_HUMAN,sp|Q9H361|PABP3_HUMAN,sp|P11940|PABP1_HUMAN,tr|A0A7I2V5W9|A0A7I2V5W9_HUMAN,tr|A0A7I2YQE4|A0A7I2YQE4_HUMAN,tr|A0A7I2V649|A0A7I2V649_HUMAN,tr|B1ANR0|B1ANR0_HUMAN,tr|A0A7I2V4L7|A0A7I2V4L7_HUMAN,tr|H0YCC8|H0YCC8_HUMAN,tr|H0YAR2|H0YAR2_HUMAN,tr|E7ERJ7|E7ERJ7_HUMAN,tr|A0A7I2V598|A0A7I2V598_HUMAN,tr|A0A7I2YQ88|A0A7I2YQ88_HUMAN,tr|H0YEQ8|H0YEQ8_HUMAN,tr|H0Y5F5|H0Y5F5_HUMAN,tr|H0YBN4|H0YBN4_HUMAN,tr|E5RGH3|E5RGH3_HUMAN,tr|A0A087WTT1|A0A087WTT1_HUMAN,tr|A0A7I2YQ90|A0A7I2YQ90_HUMAN,tr|A0A7I2V4N4|A0A7I2V4N4_HUMAN,tr|E7EQV3|E7EQV3_HUMAN" 21 1006.439 1.35 74840 2904 2 1006.433844 504.2268 Polyadenylate-binding protein 4 OS=Homo sapiens OX=9606 GN=PABPC4 PE=1 SV=1 4.37 1244 - 1.10E+06 - - - -5.0833 - 1.854 0.694 - 289.6 1 2 0 -0.0051 9 0 0 0 5.31E+08 3.93E+08 - - - 5.9513 0.9962 221125_WJC_METTL3_EV_vs_WT_F06.02912.02912.2 7.51E-07 16-Sep K.VVC[160.03]DENGSK[136.11].G "sp|Q13310|PABP4_HUMAN,sp|Q9H361|PABP3_HUMAN,sp|P11940|PABP1_HUMAN,tr|A0A7I2V5W9|A0A7I2V5W9_HUMAN,tr|A0A7I2YQE4|A0A7I2YQE4_HUMAN,tr|A0A7I2V649|A0A7I2V649_HUMAN,tr|B1ANR0|B1ANR0_HUMAN,tr|A0A7I2V4L7|A0A7I2V4L7_HUMAN,tr|H0YCC8|H0YCC8_HUMAN,tr|H0YAR2|H0YAR2_HUMAN,tr|E7ERJ7|E7ERJ7_HUMAN,tr|A0A7I2V598|A0A7I2V598_HUMAN,tr|A0A7I2YQ88|A0A7I2YQ88_HUMAN,tr|H0YEQ8|H0YEQ8_HUMAN,tr|H0Y5F5|H0Y5F5_HUMAN,tr|H0YBN4|H0YBN4_HUMAN,tr|E5RGH3|E5RGH3_HUMAN,tr|A0A087WTT1|A0A087WTT1_HUMAN,tr|A0A7I2YQ90|A0A7I2YQ90_HUMAN,tr|A0A7I2V4N4|A0A7I2V4N4_HUMAN,tr|E7EQV3|E7EQV3_HUMAN" 21 1014.4532 1.35 74844 2912 2 1014.447241 508.2339 Polyadenylate-binding protein 4 OS=Homo sapiens OX=9606 GN=PABPC4 PE=1 SV=1 4.37 1245 - 3.44E+06 - - - -5.8347 - 1.783 0.586 - 239.2 1 2 0 -0.0059 9 0 0 0 5.33E+08 3.94E+08 - - - 5.0404 0.9928 221125_WJC_METTL3_EV_vs_WT_F06.02915.02915.2 0.0514 16-Oct K.LASTSC[160.03]GQK.S "sp|O75410|TACC1_HUMAN,tr|E7EVI4|E7EVI4_HUMAN,tr|E5RFM9|E5RFM9_HUMAN,tr|A0A0C4DGD5|A0A0C4DGD5_HUMAN,tr|R4GMT7|R4GMT7_HUMAN,tr|H0YAY0|H0YAY0_HUMAN,tr|A0A0C4DGD3|A0A0C4DGD3_HUMAN,tr|H0YBT8|H0YBT8_HUMAN,tr|E7ET87|E7ET87_HUMAN" 9 950.4491 1.19 74845 2915 2 950.444791 476.2318 Transforming acidic coiled-coil-containing protein 1 OS=Homo sapiens OX=9606 GN=TACC1 PE=1 SV=2 8.22 1245.4 - 1.21E+06 - - - -4.5663 - 1.626 0.345 - 270.6 1 2 0 -0.0043 9 0 0 0 1.87E+08 1.58E+08 - - - 2.9942 0.9929 221125_WJC_METTL3_EV_vs_WT_F06.02919.02919.2 0.00644 16-Oct K.LASTSC[160.03]GQK[136.11].S "sp|O75410|TACC1_HUMAN,tr|E7EVI4|E7EVI4_HUMAN,tr|E5RFM9|E5RFM9_HUMAN,tr|A0A0C4DGD5|A0A0C4DGD5_HUMAN,tr|R4GMT7|R4GMT7_HUMAN,tr|H0YAY0|H0YAY0_HUMAN,tr|A0A0C4DGD3|A0A0C4DGD3_HUMAN,tr|H0YBT8|H0YBT8_HUMAN,tr|E7ET87|E7ET87_HUMAN" 9 958.4633 1.18 74848 2919 2 958.458217 480.2389 Transforming acidic coiled-coil-containing protein 1 OS=Homo sapiens OX=9606 GN=TACC1 PE=1 SV=2 8.22 1245.8 - 1.57E+06 - - - -5.3356 - 2.053 0.337 - 288.3 1 2 0 -0.0051 9 0 0 0 1.86E+08 1.58E+08 - - - 3.6095 0.98 221125_WJC_METTL3_EV_vs_WT_F06.02922.02922.2 0.0839 14-Aug R.VEEEAAQK.N sp|P35579|MYH9_HUMAN 1 902.4345 1.25 74849 2922 2 902.429763 452.2245 Myosin-9 OS=Homo sapiens OX=9606 GN=MYH9 PE=1 SV=4 4.25 1246.2 - 9.38E+06 - - - -5.2779 - 1.501 0.302 - 144.4 1 2 0 -0.0048 8 0 0 0 1.14E+09 9.14E+08 - - - 2.495 0.9692 221125_WJC_METTL3_EV_vs_WT_F06.02933.02933.2 0.00715 12-Jul R.C[160.03]ESAEPR.H sp|O94906|PRP6_HUMAN 1 847.3494 3.16 74852 2933 2 847.344556 424.682 Pre-mRNA-processing factor 6 OS=Homo sapiens OX=9606 GN=PRPF6 PE=1 SV=1 4.53 1247.8 - 3.20E+06 - - - -5.7367 - 1.355 0.323 - 202.6 1 2 0 -0.0049 7 0 0 0 1.14E+08 3.62E+07 - - - 2.3878 0.9867 221125_WJC_METTL3_EV_vs_WT_F06.02937.02937.2 0.00157 14-Aug R.EAPDTAEK[136.11].A "sp|Q96CT7|CC124_HUMAN,tr|M0R2F5|M0R2F5_HUMAN" 2 867.4065 0.85 74855 2937 2 867.401863 434.7105 Coiled-coil domain-containing protein 124 OS=Homo sapiens OX=9606 GN=CCDC124 PE=1 SV=1 4.14 1248.2 - 1.82E+06 - - - -5.3769 - 1.468 0.373 - 250.4 1 2 0 -0.0047 8 0 0 0 3.47E+08 4.08E+08 - - - 2.9523 0.9841 221125_WJC_METTL3_EV_vs_WT_F06.02943.02943.2 0.000136 12-Sep K.SPDDPSR[166.11].Y "sp|P06733|ENOA_HUMAN,tr|A0A2R8Y6G6|A0A2R8Y6G6_HUMAN" 2 782.3434 1.68 74857 2943 2 782.338429 392.179 Alpha-enolase OS=Homo sapiens OX=9606 GN=ENO1 PE=1 SV=2 4.21 1248.9 - 1.49E+07 - - - -6.3757 - 1.558 0.413 - 333.9 1 2 0 -0.005 7 0 0 0 2.07E+09 1.23E+09 - - - 3.4948 0.9906 221125_WJC_METTL3_EV_vs_WT_F06.02945.02945.2 0.0539 14-Aug R.VEEEAAQK[136.11].N sp|P35579|MYH9_HUMAN 1 910.4487 1.25 74858 2945 2 910.443531 456.2316 Myosin-9 OS=Homo sapiens OX=9606 GN=MYH9 PE=1 SV=4 4.25 1249.2 - 4.31E+07 - - - -5.706 - 1.736 0.39 - 192.4 1 2 0 -0.0052 8 0 0 0 1.14E+09 9.14E+08 - - - 3.5835 0.9419 221125_WJC_METTL3_EV_vs_WT_F06.02946.02946.2 0.173 14-Jul K.ISEQSDAK[136.11].L sp|P25705|ATPA_HUMAN 1 884.4331 1.25 74859 2946 2 884.428305 443.2238 "ATP synthase subunit alpha, mitochondrial OS=Homo sapiens OX=9606 GN=ATP5F1A PE=1 SV=1" 4.37 1249.2 - 1.23E+07 - - - -5.3944 - 1.367 0.225 - 127.5 1 2 0 -0.0048 8 0 0 0 1.23E+09 9.87E+08 - - - 1.6442 0.99 221125_WJC_METTL3_EV_vs_WT_F06.02949.02949.2 0.16 14-Sep K.ISEQSDAK.L sp|P25705|ATPA_HUMAN 1 876.4189 1.25 74860 2949 2 876.418469 439.2167 "ATP synthase subunit alpha, mitochondrial OS=Homo sapiens OX=9606 GN=ATP5F1A PE=1 SV=1" 4.37 1249.6 - 1.49E+07 - - - -0.4644 - 1.358 0.091 - 226.5 1 2 0 -0.0004 8 0 0 0 1.23E+09 9.85E+08 - - - 0.6359 0.8078 221125_WJC_METTL3_EV_vs_WT_F06.02950.02950.2 0.0197 14-Jun R.EAPDTAEK.A "sp|Q96CT7|CC124_HUMAN,tr|M0R2F5|M0R2F5_HUMAN" 2 859.3923 0.85 74861 2950 2 859.383858 430.7034 Coiled-coil domain-containing protein 124 OS=Homo sapiens OX=9606 GN=CCDC124 PE=1 SV=1 4.14 1249.6 - 3.70E+06 - - - -9.8546 - 1.449 0.244 - 117.8 1 2 0 -0.0085 8 0 0 0 3.47E+08 4.09E+08 - - - 1.9591 0.9907 221125_WJC_METTL3_EV_vs_WT_F06.02963.02963.2 0.0009 16-Sep R.IGGSTDTGK.H sp|P46977|STT3A_HUMAN 1 834.4083 1.09 74866 2963 2 834.403352 418.2114 Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit STT3A OS=Homo sapiens OX=9606 GN=STT3A PE=1 SV=2 5.84 1251.2 - 4.82E+06 - - - -5.9431 - 1.59 0.461 - 158.8 1 2 0 -0.005 9 0 0 0 2.13E+08 1.94E+08 - - - 3.786 0.9972 221125_WJC_METTL3_EV_vs_WT_F06.02997.02997.2 4.09E-06 18-Nov R.VVANGDTANK.V sp|Q9BV20|MTNA_HUMAN 1 987.4985 1.8 74881 2997 2 987.493555 494.7565 Methylthioribose-1-phosphate isomerase OS=Homo sapiens OX=9606 GN=MRI1 PE=1 SV=1 5.81 1255.6 - 1.41E+06 - - - -5.0309 - 2.118 0.464 - 342.7 1 2 0 -0.005 10 0 0 0 6.41E+07 3.56E+07 - - - 4.5613 0.9701 221125_WJC_METTL3_EV_vs_WT_F06.02998.02998.2 0.000506 14-Oct R.VLHAEQEK.A sp|Q5T1M5|FKB15_HUMAN 1 952.4978 1.03 74882 2998 2 952.491343 477.2562 FK506-binding protein 15 OS=Homo sapiens OX=9606 GN=FKBP15 PE=1 SV=2 5.4 1255.7 - 986660 - - - -6.7738 - 1.478 0.389 - 381.7 1 2 0 -0.0065 8 0 0 0 1.78E+07 1.72E+07 - - - 3.0904 0.9932 221125_WJC_METTL3_EV_vs_WT_F06.03002.03002.2 0.00887 14-Jul K.IEQDTDTK.L sp|O00425|IF2B3_HUMAN 1 948.44 1.79 74884 3002 2 948.436009 475.2273 Insulin-like growth factor 2 mRNA-binding protein 3 OS=Homo sapiens OX=9606 GN=IGF2BP3 PE=1 SV=2 4.03 1256.3 - 1.35E+06 - - - -4.2143 - 1.491 0.346 - 136.4 1 2 0 -0.004 8 0 0 0 7.51E+07 4.19E+07 - - - 2.8 0.9849 221125_WJC_METTL3_EV_vs_WT_F06.03003.03003.2 0.0731 14-Jul K.EAETPQAK[136.11].K "sp|Q14978|NOLC1_HUMAN,tr|A0A0A0MRM9|A0A0A0MRM9_HUMAN" 2 880.4382 2.04 74885 3003 2 880.434675 441.2264 Nucleolar and coiled-body phosphoprotein 1 OS=Homo sapiens OX=9606 GN=NOLC1 PE=1 SV=2 4.53 1256.3 - 3.71E+06 - - - -3.9605 - 1.361 0.265 - 252.4 1 2 0 -0.0035 8 0 0 0 1.44E+09 7.05E+08 - - - 1.9268 0.9935 221125_WJC_METTL3_EV_vs_WT_F06.03005.03005.2 0.014 14-Sep K.IEQDTDTK[136.11].L sp|O00425|IF2B3_HUMAN 1 956.4542 1.79 74887 3005 2 956.449901 479.2344 Insulin-like growth factor 2 mRNA-binding protein 3 OS=Homo sapiens OX=9606 GN=IGF2BP3 PE=1 SV=2 4.03 1256.6 - 920887 - - - -4.501 - 1.82 0.298 - 235.8 1 2 0 -0.0043 8 0 0 0 7.51E+07 4.19E+07 - - - 3.0467 0.8362 221125_WJC_METTL3_EV_vs_WT_F06.03009.03009.2 0.826 12-Jun K.SSQEEVR[166.11].S sp|P52597|HNRPF_HUMAN 1 843.3962 0.84 74889 3009 2 843.391777 422.7054 Heterogeneous nuclear ribonucleoprotein F OS=Homo sapiens OX=9606 GN=HNRNPF PE=1 SV=3 4.53 1257.1 - 1.47E+07 - - - -5.2206 - 1.408 0.099 - 274.3 2 2 0 -0.0044 7 0 0 0 1.28E+09 1.53E+09 - - - 0.7205 0.9972 221125_WJC_METTL3_EV_vs_WT_F06.03013.03013.2 5.26E-05 14-Sep K.MVATTK[136.11]PK[136.11].A "sp|Q14978|NOLC1_HUMAN,tr|A0A0A0MRM9|A0A0A0MRM9_HUMAN" 2 890.523 1.74 74893 3013 2 890.518754 446.2688 Nucleolar and coiled-body phosphoprotein 1 OS=Homo sapiens OX=9606 GN=NOLC1 PE=1 SV=2 10 1257.2 - 4.10E+06 - - - -4.7949 - 1.727 0.493 - 242.6 1 2 0 -0.0043 8 0 0 0 2.20E+08 1.26E+08 - - - 4.3288 0.9981 221125_WJC_METTL3_EV_vs_WT_F06.03014.03014.2 3.63E-05 18-Oct R.VVANGDTANK[136.11].V sp|Q9BV20|MTNA_HUMAN 1 995.5127 1.87 74894 3014 2 995.508096 498.7636 Methylthioribose-1-phosphate isomerase OS=Homo sapiens OX=9606 GN=MRI1 PE=1 SV=1 5.81 1257.3 - 2.56E+06 - - - -4.6479 - 1.98 0.521 - 248.5 1 2 0 -0.0046 10 0 0 0 6.41E+07 3.44E+07 - - - 4.7944 0.9926 221125_WJC_METTL3_EV_vs_WT_F06.03024.03024.2 0.686 12-Sep K.SHIMAAK[136.11].A "sp|P48643|TCPE_HUMAN,tr|E9PCA1|E9PCA1_HUMAN,tr|E7ENZ3|E7ENZ3_HUMAN,tr|H0Y914|H0Y914_HUMAN" 4 764.4094 0.03 74900 3024 2 764.405738 383.212 T-complex protein 1 subunit epsilon OS=Homo sapiens OX=9606 GN=CCT5 PE=1 SV=1 8.49 1258.5 - 2.76E+07 - - - -4.8482 - 2.003 0.262 - 504.6 1 2 0 -0.0037 7 0 0 0 6.42E+07 2.08E+09 - - - 3.176 0.9719 221125_WJC_METTL3_EV_vs_WT_F06.03026.03026.2 0.026 16-Aug R.GPAPGSGTR[166.11].Q "sp|Q6SPF0|SAMD1_HUMAN,tr|E9PIW9|E9PIW9_HUMAN" 2 808.4067 2.68 74902 3026 2 808.402473 405.2106 Sterile alpha motif domain-containing protein 1 OS=Homo sapiens OX=9606 GN=SAMD1 PE=1 SV=1 9.75 1258.7 - 980063 - - - -5.2102 - 1.646 0.226 - 232.1 1 2 0 -0.0042 9 0 0 0 1.59E+08 5.94E+07 - - - 2.1507 0.9265 221125_WJC_METTL3_EV_vs_WT_F06.03040.03040.2 0.238 14-Aug R.SPGSQGVR.D sp|O43678|NDUA2_HUMAN 1 786.3984 1.42 74906 3040 2 786.394354 394.2065 NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 2 OS=Homo sapiens OX=9606 GN=NDUFA2 PE=1 SV=3 9.47 1260.7 - 3.57E+06 - - - -5.164 - 1.363 0.184 - 202.7 1 2 0 -0.0041 8 0 0 0 2.54E+08 1.79E+08 - - - 1.3328 0.9863 221125_WJC_METTL3_EV_vs_WT_F06.03053.03053.2 0.208 16-Aug R.APVSGTQEK[136.11].N "sp|P04049|RAF1_HUMAN,tr|H7C155|H7C155_HUMAN" 2 923.4804 0.68 74911 3053 2 923.477155 462.7475 RAF proto-oncogene serine\threonine-protein kinase OS=Homo sapiens OX=9606 GN=RAF1 PE=1 SV=1 6.05 1262.3 - 1.51E+06 - - - -3.4716 - 1.408 0.229 - 208.8 1 2 0 -0.0032 9 0 0 0 2.97E+07 4.39E+07 - - - 1.7213 0.9832 221125_WJC_METTL3_EV_vs_WT_F06.03057.03057.2 0.0199 16-Sep R.APVSGTQEK.N "sp|P04049|RAF1_HUMAN,tr|H7C155|H7C155_HUMAN" 2 915.4662 0.67 74913 3057 2 915.461607 458.7404 RAF proto-oncogene serine\threonine-protein kinase OS=Homo sapiens OX=9606 GN=RAF1 PE=1 SV=1 6.05 1262.8 - 938436 - - - -4.9745 - 1.468 0.313 - 253.2 1 2 0 -0.0046 9 0 0 0 2.95E+07 4.37E+07 - - - 2.462 0.9245 221125_WJC_METTL3_EV_vs_WT_F06.03061.03061.2 0.611 12-May K.EAVESQR[166.11].M sp|P40222|TXLNA_HUMAN 1 827.4013 1.25 74915 3061 2 827.39728 414.7079 Alpha-taxilin OS=Homo sapiens OX=9606 GN=TXLNA PE=1 SV=3 4.53 1263.3 - 5.68E+06 - - - -4.8175 - 1.277 0.178 - 93.5 1 2 0 -0.004 7 0 0 0 1.74E+08 1.40E+08 - - - 1.1292 0.9888 221125_WJC_METTL3_EV_vs_WT_F06.03065.03065.2 0.144 14-Jul R.AEAPADQR.S sp|Q9H0W5|CCDC8_HUMAN 1 856.4039 3.19 74917 3065 2 856.400817 429.2092 Coiled-coil domain-containing protein 8 OS=Homo sapiens OX=9606 GN=CCDC8 PE=1 SV=2 4.37 1263.7 - 6.16E+06 - - - -3.5941 - 1.394 0.259 - 238.6 1 2 0 -0.0031 8 0 0 0 1.94E+08 6.09E+07 - - - 1.9548 0.9136 221125_WJC_METTL3_EV_vs_WT_F06.03067.03067.2 1.22 12-Jul K.DAEAVQK.F sp|Q15388|TOM20_HUMAN 1 759.3763 1.23 74918 3067 2 759.372484 380.6954 Mitochondrial import receptor subunit TOM20 homolog OS=Homo sapiens OX=9606 GN=TOMM20 PE=1 SV=1 4.37 1263.9 - 1.61E+07 - - - -5.0028 - 1.337 0.157 - 181.7 1 2 0 -0.0038 7 0 0 0 4.66E+08 3.78E+08 - - - 1.1196 0.9339 221125_WJC_METTL3_EV_vs_WT_F06.03068.03068.2 0.00162 14-Jul R.GVSTC[160.03]STR.F "sp|P13646|K1C13_HUMAN,tr|K7EMJ2|K7EMJ2_HUMAN,tr|K7ERE3|K7ERE3_HUMAN,tr|K7EQH6|K7EQH6_HUMAN" 4 866.3916 2.32 74919 3068 2 866.383362 434.2031 "Keratin, type I cytoskeletal 13 OS=Homo sapiens OX=9606 GN=KRT13 PE=1 SV=4" 8.25 1264 - 7.24E+06 - - - -9.5269 - 1.442 0.405 - 156.5 1 2 0 -0.0083 8 0 0 0 1.52E+08 6.58E+07 - - - 3.1337 0.8296 221125_WJC_METTL3_EV_vs_WT_F06.03081.03081.2 0.597 14-Aug R.APSADTAR.S sp|Q9BUA3|SPNDC_HUMAN 1 787.3824 2.26 74926 3081 2 787.376222 394.6985 Spindlin interactor and repressor of chromatin-binding protein OS=Homo sapiens OX=9606 GN=SPINDOC PE=1 SV=3 5.88 1265.4 - 8.06E+06 - - - -7.8856 - 1.585 0.205 - 194 1 2 0 -0.0062 8 0 0 0 2.67E+08 1.18E+08 - - - 1.9423 0.9815 221125_WJC_METTL3_EV_vs_WT_F06.03094.03094.2 0.644 12-Jul R.LQQQEER.R sp|Q02040|AK17A_HUMAN 1 929.4567 1.33 74934 3094 2 929.453789 465.7356 A-kinase anchor protein 17A OS=Homo sapiens OX=9606 GN=AKAP17A PE=1 SV=2 4.53 1266.8 - 1.34E+06 - - - -3.0878 - 1.575 0.108 - 197.6 1 2 0 -0.0029 7 0 0 0 4.38E+07 3.30E+07 - - - 1.2771 0.9822 221125_WJC_METTL3_EV_vs_WT_F06.03100.03100.2 0.021 14-Jun K.IENHEGVR[166.11].R "sp|P14618|KPYM_HUMAN,tr|H3BQ34|H3BQ34_HUMAN,tr|B4DNK4|B4DNK4_HUMAN,tr|A0A804F6T5|A0A804F6T5_HUMAN,tr|H3BTN5|H3BTN5_HUMAN,tr|H3BR70|H3BR70_HUMAN,tr|A0A804F729|A0A804F729_HUMAN" 7 962.4809 1.47 74938 3100 2 962.47655 482.2477 Pyruvate kinase PKM OS=Homo sapiens OX=9606 GN=PKM PE=1 SV=4 5.4 1267.6 - 1.07E+06 - - - -4.5331 - 1.384 0.286 - 95.5 1 2 0 -0.0044 8 0 0 0 9.75E+07 6.62E+07 - - - 2.1321 0.796 221125_WJC_METTL3_EV_vs_WT_F06.03105.03105.2 0.434 16-Jun R.VAPSSSDPK[136.11].S sp|Q8N1G2|CMTR1_HUMAN 1 894.4538 1.61 74941 3105 2 894.448761 448.2342 Cap-specific mRNA (nucleoside-2'-O-)-methyltransferase 1 OS=Homo sapiens OX=9606 GN=CMTR1 PE=1 SV=1 5.81 1268.2 - 978675 - - - -5.647 - 1.247 0.144 - 113.1 1 2 0 -0.005 9 0 0 0 4.00E+07 2.48E+07 - - - 0.7416 0.9946 221125_WJC_METTL3_EV_vs_WT_F06.03106.03106.2 0.0838 14-Oct K.IENHEGVR.R "sp|P14618|KPYM_HUMAN,tr|H3BQ34|H3BQ34_HUMAN,tr|B4DNK4|B4DNK4_HUMAN,tr|A0A804F6T5|A0A804F6T5_HUMAN,tr|H3BTN5|H3BTN5_HUMAN,tr|H3BR70|H3BR70_HUMAN,tr|A0A804F729|A0A804F729_HUMAN" 7 952.4726 1.45 74942 3106 2 952.468829 477.2436 Pyruvate kinase PKM OS=Homo sapiens OX=9606 GN=PKM PE=1 SV=4 5.4 1268.2 - 2.75E+06 - - - -4.0043 - 1.815 0.276 - 385.5 1 2 0 -0.0038 8 0 0 0 9.75E+07 6.74E+07 - - - 2.8761 0.9901 221125_WJC_METTL3_EV_vs_WT_F06.03113.03113.2 0.00126 16-Aug K.VVSETNDTK.V sp|P05783|K1C18_HUMAN 1 991.4822 1.91 74944 3113 2 991.477907 496.7484 "Keratin, type I cytoskeletal 18 OS=Homo sapiens OX=9606 GN=KRT18 PE=1 SV=2" 4.37 1269.2 - 1.19E+06 - - - -4.3349 - 1.569 0.296 - 184.5 1 2 0 -0.0043 9 0 0 0 6.77E+08 3.54E+08 - - - 2.529 0.9885 221125_WJC_METTL3_EV_vs_WT_F06.03115.03115.2 0.00259 14-Aug K.EAETPQAK.K "sp|Q14978|NOLC1_HUMAN,tr|A0A0A0MRM9|A0A0A0MRM9_HUMAN" 2 872.424 2.04 74945 3115 2 872.419761 437.2193 Nucleolar and coiled-body phosphoprotein 1 OS=Homo sapiens OX=9606 GN=NOLC1 PE=1 SV=2 4.53 1269.4 - 7.44E+06 - - - -4.8153 - 1.365 0.37 - 304.7 1 2 0 -0.0042 8 0 0 0 1.44E+09 7.05E+08 - - - 2.7109 0.9943 221125_WJC_METTL3_EV_vs_WT_F06.03117.03117.2 0.0195 14-Jun K.GNVETC[160.03]AK.A sp|O00425|IF2B3_HUMAN 1 877.3964 0.93 74947 3117 2 877.393269 439.7055 Insulin-like growth factor 2 mRNA-binding protein 3 OS=Homo sapiens OX=9606 GN=IGF2BP3 PE=1 SV=2 5.99 1269.5 - 5.40E+06 - - - -3.5309 - 1.346 0.346 - 192.3 1 2 0 -0.0031 8 0 0 0 2.30E+08 2.47E+08 - - - 2.4917 0.9957 221125_WJC_METTL3_EV_vs_WT_F06.03118.03118.2 0.00313 16-Sep K.VVSETNDTK[136.11].V sp|P05783|K1C18_HUMAN 1 999.4964 1.91 74948 3118 2 999.491876 500.7555 "Keratin, type I cytoskeletal 18 OS=Homo sapiens OX=9606 GN=KRT18 PE=1 SV=2" 4.37 1269.6 - 1.17E+06 - - - -4.5313 - 1.676 0.405 - 195.8 1 2 0 -0.0045 9 0 0 0 6.77E+08 3.54E+08 - - - 3.5249 0.9906 221125_WJC_METTL3_EV_vs_WT_F06.03121.03121.2 0.00354 12-Jul K.LEDENNR.Y "sp|P82094|TMF1_HUMAN,tr|A0A2R8Y7M0|A0A2R8Y7M0_HUMAN" 2 888.3937 0.91 74949 3121 2 888.388957 445.2041 TATA element modulatory factor OS=Homo sapiens OX=9606 GN=TMF1 PE=1 SV=2 4.14 1270 - 8.12E+06 - - - -5.3659 - 1.447 0.42 - 161.6 1 2 0 -0.0048 7 0 0 0 4.33E+08 4.73E+08 - - - 3.3124 0.921 221125_WJC_METTL3_EV_vs_WT_F06.03126.03126.2 0.49 12-Jun K.ATVEDEK[136.11].L "sp|P11142|HSP7C_HUMAN,tr|E9PNE6|E9PNE6_HUMAN,tr|A8K7Q2|A8K7Q2_HUMAN,tr|E9PKE3|E9PKE3_HUMAN,tr|E9PM13|E9PM13_HUMAN,tr|E9PS65|E9PS65_HUMAN" 6 798.3851 0.47 74952 3126 2 798.381428 400.1998 Heat shock cognate 71 kDa protein OS=Homo sapiens OX=9606 GN=HSPA8 PE=1 SV=1 4.14 1270.6 - 9.41E+06 - - - -4.5529 - 1.132 0.207 - 162 1 2 0 -0.0036 7 0 0 0 3.67E+08 7.79E+08 - - - 0.9616 0.9963 221125_WJC_METTL3_EV_vs_WT_F06.03127.03127.2 0.00375 14-Sep R.K[136.11]VTAAMGK[136.11].K "sp|P61353|RL27_HUMAN,tr|K7ELC7|K7ELC7_HUMAN" 2 820.4812 0.92 74953 3127 2 820.477265 411.2479 60S ribosomal protein L27 OS=Homo sapiens OX=9606 GN=RPL27 PE=1 SV=2 10 1270.6 - 6.57E+06 - - - -4.746 - 1.922 0.391 - 297.9 1 2 0 -0.0039 8 0 0 0 2.66E+08 2.89E+08 - - - 3.8982 0.9975 221125_WJC_METTL3_EV_vs_WT_F06.03131.03131.2 0.00166 14-Aug K.VENSNTVR[166.11].T "sp|Q14202|ZMYM3_HUMAN,tr|A6NHB5|A6NHB5_HUMAN,tr|A6NHN7|A6NHN7_HUMAN" 3 927.4649 0.68 74955 3131 2 927.46351 464.7397 Zinc finger MYM-type protein 3 OS=Homo sapiens OX=9606 GN=ZMYM3 PE=1 SV=2 5.97 1271.1 - 1.06E+06 - - - -1.53 - 1.709 0.181 - 174.3 1 2 0 -0.0014 8 0 0 0 1.85E+07 2.70E+07 - - - 1.9937 0.7675 221125_WJC_METTL3_EV_vs_WT_F06.03173.03173.2 0.181 14-Jun K.DVESDSAK[136.11].Q "sp|P07237|PDIA1_HUMAN,tr|A0A7P0TA97|A0A7P0TA97_HUMAN,tr|A0A7P0T8C0|A0A7P0T8C0_HUMAN,tr|H7BZ94|H7BZ94_HUMAN,tr|A0A7P0TA71|A0A7P0TA71_HUMAN,tr|I3L4M2|I3L4M2_HUMAN,tr|A0A7P0T9D6|A0A7P0T9D6_HUMAN,tr|A0A7P0T9K9|A0A7P0T9K9_HUMAN,tr|A0A7P0Z4S2|A0A7P0Z4S2_HUMAN,tr|A0A7P0TA35|A0A7P0TA35_HUMAN,tr|A0A7P0TAX9|A0A7P0TAX9_HUMAN,tr|I3L514|I3L514_HUMAN,tr|A0A7P0TB26|A0A7P0TB26_HUMAN,tr|A0A7P0T9U6|A0A7P0T9U6_HUMAN,tr|I3L0S0|I3L0S0_HUMAN,tr|I3L3P5|I3L3P5_HUMAN,tr|A0A7P0T8J3|A0A7P0T8J3_HUMAN,tr|A0A7P0Z4J0|A0A7P0Z4J0_HUMAN,tr|A0A7P0T8X1|A0A7P0T8X1_HUMAN" 19 857.3858 1.48 74975 3173 2 857.379283 429.7002 Protein disulfide-isomerase OS=Homo sapiens OX=9606 GN=P4HB PE=1 SV=3 4.03 1276 - 3.91E+06 - - - -7.5917 - 1.322 0.223 - 97.4 1 2 0 -0.0065 8 0 0 0 5.96E+08 4.04E+08 - - - 1.5279 0.9631 221125_WJC_METTL3_EV_vs_WT_F06.03178.03178.2 1.64 12-Jul R.SSQLSSR.R "sp|Q9NQS7|INCE_HUMAN,tr|E9PM67|E9PM67_HUMAN" 2 763.3824 1.26 74977 3178 2 763.37934 382.6985 Inner centromere protein OS=Homo sapiens OX=9606 GN=INCENP PE=1 SV=3 9.47 1276.6 - 3.40E+06 - - - -4.0491 - 1.308 0.187 - 323.1 1 2 0 -0.0031 7 0 0 0 9.44E+07 7.48E+07 - - - 1.272 0.7956 221125_WJC_METTL3_EV_vs_WT_F06.03183.03183.2 1.12 12-Jun R.QVSDVQK[136.11].R "sp|Q13263|TIF1B_HUMAN,tr|M0R3C0|M0R3C0_HUMAN" 2 810.4327 0.81 74979 3183 2 810.428562 406.2236 Transcription intermediary factor 1-beta OS=Homo sapiens OX=9606 GN=TRIM28 PE=1 SV=5 5.84 1277.2 - 2.87E+07 - - - -5.0837 - 1.098 0.154 - 153.1 1 2 0 -0.0041 7 0 0 0 5.44E+08 6.68E+08 - - - 0.4734 0.9961 221125_WJC_METTL3_EV_vs_WT_F06.03190.03190.2 0.00107 14-Sep R.IQAESGC[160.03]K.L sp|Q96I24|FUBP3_HUMAN 1 891.412 1.76 74982 3190 2 891.408117 446.7133 Far upstream element-binding protein 3 OS=Homo sapiens OX=9606 GN=FUBP3 PE=1 SV=2 5.99 1278 - 2.20E+07 - - - -4.3751 - 1.661 0.399 - 236.6 1 2 0 -0.0039 8 0 0 0 6.98E+09 3.97E+09 - - - 3.5171 0.9927 221125_WJC_METTL3_EV_vs_WT_F06.03193.03193.2 0.16 14-Sep R.IQAESGC[160.03]K[136.11].L sp|Q96I24|FUBP3_HUMAN 1 899.4262 1.76 74983 3193 2 899.422053 450.7204 Far upstream element-binding protein 3 OS=Homo sapiens OX=9606 GN=FUBP3 PE=1 SV=2 5.99 1278.4 - 2.56E+07 - - - -4.6296 - 1.678 0.328 - 227.3 1 2 0 -0.0042 8 0 0 0 6.98E+09 3.97E+09 - - - 3.0234 0.8988 221125_WJC_METTL3_EV_vs_WT_F06.03201.03201.2 1 12-Jul K.GEQQIQK[136.11].A sp|Q9Y5B9|SP16H_HUMAN 1 837.4436 0.96 74989 3201 2 837.439889 419.7291 FACT complex subunit SPT16 OS=Homo sapiens OX=9606 GN=SUPT16H PE=1 SV=1 6 1279.2 - 9.63E+06 - - - -4.4087 - 1.147 0.166 - 243.9 1 2 0 -0.0037 7 0 0 0 1.96E+08 2.04E+08 - - - 0.7005 0.9931 221125_WJC_METTL3_EV_vs_WT_F06.03211.03211.2 0.000683 12-Jul R.NQGGYDR.Y sp|P98179|RBM3_HUMAN 1 808.3464 0.98 74994 3211 2 808.342536 405.1805 RNA-binding protein 3 OS=Homo sapiens OX=9606 GN=RBM3 PE=1 SV=1 5.84 1280.5 - 1.66E+07 - - - -4.7554 - 1.419 0.41 - 239.5 1 2 0 -0.0038 7 0 0 0 5.37E+08 5.50E+08 - - - 3.1769 0.9811 221125_WJC_METTL3_EV_vs_WT_F06.03224.03224.2 0.00514 12-Jun R.EPSNPER.L "sp|P23588|IF4B_HUMAN,tr|E7EX17|E7EX17_HUMAN,tr|F8VSC7|F8VSC7_HUMAN,tr|F8VYE9|F8VYE9_HUMAN,tr|F8VRU1|F8VRU1_HUMAN,tr|F8VX11|F8VX11_HUMAN,tr|F8W0K0|F8W0K0_HUMAN,tr|F8VP89|F8VP89_HUMAN" 8 827.3773 1.49 74998 3224 2 827.373274 414.6959 Eukaryotic translation initiation factor 4B OS=Homo sapiens OX=9606 GN=EIF4B PE=1 SV=2 4.53 1282.3 - 5.42E+06 - - - -4.9216 - 1.323 0.324 - 182.7 1 2 0 -0.0041 7 0 0 0 4.15E+08 2.78E+08 - - - 2.3197 0.8199 221125_WJC_METTL3_EV_vs_WT_F06.03227.03227.2 16.7 12-Apr K.KEEEEEK.E "sp|A6NE52|WDR97_HUMAN,sp|Q9BT43|RPC7L_HUMAN,sp|Q8IYE0|CC146_HUMAN,sp|Q14432|PDE3A_HUMAN,sp|Q13936|CAC1C_HUMAN,sp|Q8TAK5|GABP2_HUMAN,sp|Q8IZU1|FAM9A_HUMAN,sp|P27824|CALX_HUMAN,sp|O75400|PR40A_HUMAN,sp|P35269|T2FA_HUMAN,tr|A0A7P0T937|A0A7P0T937_HUMAN,tr|A0A7P0T840|A0A7P0T840_HUMAN,tr|C9JRR4|C9JRR4_HUMAN,tr|Q5SZG2|Q5SZG2_HUMAN,tr|A0A7P0TB65|A0A7P0TB65_HUMAN,tr|A0A087WUX4|A0A087WUX4_HUMAN,tr|A0A804HIR0|A0A804HIR0_HUMAN,tr|A0A804HJR1|A0A804HJR1_HUMAN,tr|A0A804HIZ0|A0A804HIZ0_HUMAN,tr|M0QXD6|M0QXD6_HUMAN,tr|A0A0A0MSA1|A0A0A0MSA1_HUMAN,tr|A0A804HI37|A0A804HI37_HUMAN,tr|A0A7P0TAE9|A0A7P0TAE9_HUMAN,tr|E9PDI6|E9PDI6_HUMAN,tr|D6RGY2|D6RGY2_HUMAN,tr|A0A7P0T8G1|A0A7P0T8G1_HUMAN,tr|F5GY28|F5GY28_HUMAN,tr|A0A804HJB6|A0A804HJB6_HUMAN,tr|A0A7P0Z484|A0A7P0Z484_HUMAN,tr|A0A804HKE9|A0A804HKE9_HUMAN,tr|F5H522|F5H522_HUMAN,tr|A6NGX6|A6NGX6_HUMAN,tr|A0A804HIJ8|A0A804HIJ8_HUMAN,tr|A0A804HKC4|A0A804HKC4_HUMAN,tr|A0A7N4I394|A0A7N4I394_HUMAN,tr|A0A7P0T9L0|A0A7P0T9L0_HUMAN,tr|A0A0A0MR67|A0A0A0MR67_HUMAN" 37 919.4135 108.25 75000 3227 2 919.410872 460.714 WD repeat-containing protein 97 OS=Homo sapiens OX=9606 GN=WDR97 PE=2 SV=2 4.33 1282.5 - 2.19E+06 - - - -2.8105 - 0.939 0.092 - 102.7 1 2 0 -0.0026 7 0 0 0 6.17E+07 5.70E+05 - - - -0.4797 0.953 221125_WJC_METTL3_EV_vs_WT_F06.03239.03239.2 0.188 12-Jun R.EPSNPER[166.11].L "sp|P23588|IF4B_HUMAN,tr|E7EX17|E7EX17_HUMAN,tr|F8VSC7|F8VSC7_HUMAN,tr|F8VYE9|F8VYE9_HUMAN,tr|F8VRU1|F8VRU1_HUMAN,tr|F8VX11|F8VX11_HUMAN,tr|F8W0K0|F8W0K0_HUMAN,tr|F8VP89|F8VP89_HUMAN" 8 837.3856 2.96 75008 3239 2 837.383089 419.7001 Eukaryotic translation initiation factor 4B OS=Homo sapiens OX=9606 GN=EIF4B PE=1 SV=2 4.53 1283.8 - 2.13E+06 - - - -3.0177 - 1.124 0.157 - 183.1 1 2 0 -0.0025 7 0 0 0 4.97E+08 1.68E+08 - - - 0.5702 0.9675 221125_WJC_METTL3_EV_vs_WT_F06.03240.03240.2 0.425 16-Aug K.APQQEEGPK.G "sp|P35269|T2FA_HUMAN,tr|M0R0R9|M0R0R9_HUMAN,tr|M0QXD6|M0QXD6_HUMAN" 3 982.472 0.48 75009 3240 2 982.467732 492.2433 General transcription factor IIF subunit 1 OS=Homo sapiens OX=9606 GN=GTF2F1 PE=1 SV=2 4.53 1283.9 - 340191 - - - -4.3177 - 1.378 0.21 - 193.6 1 2 0 -0.0042 9 0 0 0 1.45E+07 3.04E+07 - - - 1.5183 0.9027 221125_WJC_METTL3_EV_vs_WT_F06.03244.03244.2 2.4 14-Jun K.REGDQEER.D "sp|Q7Z4N2|TRPM1_HUMAN,tr|A0A0G2JN34|A0A0G2JN34_HUMAN,tr|A0A0G2JMJ5|A0A0G2JMJ5_HUMAN,tr|A0A0A0MTQ9|A0A0A0MTQ9_HUMAN,tr|A0A0G2JPN6|A0A0G2JPN6_HUMAN,tr|A0A0G2JMR4|A0A0G2JMR4_HUMAN,tr|H0YM61|H0YM61_HUMAN,tr|H0YKU7|H0YKU7_HUMAN" 8 1017.4476 0.7 75011 3244 2 1017.444374 509.7311 Transient receptor potential cation channel subfamily M member 1 OS=Homo sapiens OX=9606 GN=TRPM1 PE=1 SV=2 4.41 1284.4 - 425360 - - - -3.1225 - 1.48 0.003 - 95.5 2 2 0 -0.0032 8 0 0 0 1.56E+07 2.24E+07 - - - 0.1101 0.8463 221125_WJC_METTL3_EV_vs_WT_F06.03245.03245.2 1.41 12-May R.LSEDSSR.H sp|Q9NYP9|MS18A_HUMAN 1 792.3614 0.65 75012 3245 2 792.36315 397.188 Protein Mis18-alpha OS=Homo sapiens OX=9606 GN=MIS18A PE=1 SV=1 4.37 1284.5 - 1.97E+06 - - - 2.2578 - 1.065 0.061 - 76.9 4 2 0 0.0018 7 0 0 0 1.01E+08 1.55E+08 - - - -0.5784 0.9724 221125_WJC_METTL3_EV_vs_WT_F06.03269.03269.2 0.329 12-Jun R.TYESSDR.L sp|P22735|TGM1_HUMAN 1 856.3563 10.83 75024 3269 2 856.353679 429.1854 Protein-glutamine gamma-glutamyltransferase K OS=Homo sapiens OX=9606 GN=TGM1 PE=1 SV=4 4.37 1287.4 - 4.12E+06 - - - -3.0326 - 1.068 0.231 - 160.7 1 2 0 -0.0026 7 0 0 0 7.00E+07 6.47E+06 - - - 0.9548 0.9845 221125_WJC_METTL3_EV_vs_WT_F06.03275.03275.2 0.457 14-Aug K.ISETAQQK.N "sp|O00268|TAF4_HUMAN,tr|A0A0G2JRY5|A0A0G2JRY5_HUMAN" 2 903.4662 1.71 75027 3275 2 903.462942 452.7404 Transcription initiation factor TFIID subunit 4 OS=Homo sapiens OX=9606 GN=TAF4 PE=1 SV=2 6 1288.1 - 3.18E+06 - - - -3.5629 - 1.469 0.2 - 131.6 1 2 0 -0.0032 8 0 0 0 2.28E+08 1.33E+08 - - - 1.6771 0.9773 221125_WJC_METTL3_EV_vs_WT_F06.03277.03277.2 0.0195 12-May R.ETNEPVK[136.11].T "sp|P12956|XRCC6_HUMAN,tr|B1AHC9|B1AHC9_HUMAN" 2 823.4167 1.19 75028 3277 2 823.413712 412.7156 X-ray repair cross-complementing protein 6 OS=Homo sapiens OX=9606 GN=XRCC6 PE=1 SV=2 4.53 1288.3 - 1.20E+07 - - - -3.6264 - 1.215 0.238 - 156.6 1 2 0 -0.003 7 0 0 0 5.71E+08 4.80E+08 - - - 1.415 0.9951 221125_WJC_METTL3_EV_vs_WT_F06.03279.03279.2 0.00681 12-Aug K.SNAVEDR.K "sp|O95319|CELF2_HUMAN,tr|E9PC62|E9PC62_HUMAN,tr|A0A1B0GU44|A0A1B0GU44_HUMAN,tr|A0A0J9YX66|A0A0J9YX66_HUMAN,tr|A0A1B0GUN8|A0A1B0GUN8_HUMAN,tr|Q5VZZ6|Q5VZZ6_HUMAN,tr|A0A0J9YXJ0|A0A0J9YXJ0_HUMAN,tr|V9GYD9|V9GYD9_HUMAN" 8 789.3617 0.74 75030 3279 2 789.358867 395.6881 CUGBP Elav-like family member 2 OS=Homo sapiens OX=9606 GN=CELF2 PE=1 SV=1 4.37 1288.4 - 1.23E+06 - - - -3.5839 - 1.67 0.272 - 388.8 1 2 0 -0.0028 7 0 0 0 5.15E+07 6.93E+07 - - - 2.674 0.9882 221125_WJC_METTL3_EV_vs_WT_F06.03294.03294.2 0.173 14-Jul K.ISETAQQK[136.11].N "sp|O00268|TAF4_HUMAN,tr|A0A0G2JRY5|A0A0G2JRY5_HUMAN" 2 911.4804 1.71 75039 3294 2 911.477071 456.7475 Transcription initiation factor TFIID subunit 4 OS=Homo sapiens OX=9606 GN=TAF4 PE=1 SV=2 6 1290.1 - 6.99E+06 - - - -3.6095 - 1.494 0.226 - 100 1 2 0 -0.0033 8 0 0 0 2.28E+08 1.33E+08 - - - 1.92 0.9981 221125_WJC_METTL3_EV_vs_WT_F06.03303.03303.2 2.17E-05 20-Oct K.ITSEGGDGATK.Y "sp|P07197|NFM_HUMAN,tr|E7ESP9|E7ESP9_HUMAN,tr|E7EMV2|E7EMV2_HUMAN" 3 1034.488 1.83 75044 3303 2 1034.484905 518.2513 Neurofilament medium polypeptide OS=Homo sapiens OX=9606 GN=NEFM PE=1 SV=3 4.37 1291.2 - 2.81E+06 - - - -3.0092 - 1.799 0.344 - 263.3 1 2 0 -0.0031 11 0 0 0 1.94E+08 1.06E+08 - - - 3.1694 0.8477 221125_WJC_METTL3_EV_vs_WT_F06.03313.03313.2 4.87 12-Jun K.AQIQEQK[136.11].L "sp|Q03001|DYST_HUMAN,sp|Q9UPN3|MACF1_HUMAN,tr|A0A804HL78|A0A804HL78_HUMAN,tr|H3BQK9|H3BQK9_HUMAN,tr|A0A0U1RQJ2|A0A0U1RQJ2_HUMAN,tr|A0A7P0MQR8|A0A7P0MQR8_HUMAN,tr|E9PHM6|E9PHM6_HUMAN,tr|H0Y390|H0Y390_HUMAN,tr|H3BPE1|H3BPE1_HUMAN,tr|F8W9J4|F8W9J4_HUMAN,tr|A0A7P0T890|A0A7P0T890_HUMAN,tr|A0A590UJG2|A0A590UJG2_HUMAN,tr|A0A0A6YYJ5|A0A0A6YYJ5_HUMAN,tr|F6QMI7|F6QMI7_HUMAN" 14 851.4592 4.43 75052 3313 2 851.456527 426.7369 Dystonin OS=Homo sapiens OX=9606 GN=DST PE=1 SV=4 6.05 1292.2 - 1.71E+06 - - - -3.1757 - 1.324 0.013 - 195.2 3 2 0 -0.0027 7 0 0 0 1.59E+08 3.60E+07 - - - -0.1877 0.9816 221125_WJC_METTL3_EV_vs_WT_F06.03317.03317.2 0.0029 20-Oct K.ITSEGGDGATK[136.11].Y "sp|P07197|NFM_HUMAN,tr|E7ESP9|E7ESP9_HUMAN,tr|E7EMV2|E7EMV2_HUMAN" 3 1042.5022 1.8 75054 3317 2 1042.494957 522.2584 Neurofilament medium polypeptide OS=Homo sapiens OX=9606 GN=NEFM PE=1 SV=3 4.37 1292.6 - 3.86E+06 - - - -6.965 - 1.666 0.456 - 156.8 1 2 0 -0.0073 11 0 0 0 1.95E+08 1.08E+08 - - - 3.7876 0.9991 221125_WJC_METTL3_EV_vs_WT_F06.03319.03319.2 0.00291 16-Sep R.NTTAAEEAR[166.11].Q "sp|O00410|IPO5_HUMAN,tr|E7ETV3|E7ETV3_HUMAN,tr|E7ETV8|E7ETV8_HUMAN,tr|C9JQT6|C9JQT6_HUMAN,tr|C9JZD8|C9JZD8_HUMAN,tr|E7EWK4|E7EWK4_HUMAN,tr|E7EV12|E7EV12_HUMAN,tr|E7EX05|E7EX05_HUMAN,tr|H0Y8C6|H0Y8C6_HUMAN,tr|E7EQT5|E7EQT5_HUMAN,tr|E7ESZ1|E7ESZ1_HUMAN" 11 971.4548 0.97 75056 3319 2 971.452945 486.7347 Importin-5 OS=Homo sapiens OX=9606 GN=IPO5 PE=1 SV=4 4.53 1292.8 - 411958 - - - -1.8663 - 1.821 0.31 - 520.5 1 2 0 -0.0018 9 0 0 0 1.07E+08 1.10E+08 - - - 3.0641 0.9988 221125_WJC_METTL3_EV_vs_WT_F06.03323.03323.2 0.00657 16-Sep R.NTTAAEEAR.Q "sp|O00410|IPO5_HUMAN,tr|E7ETV3|E7ETV3_HUMAN,tr|E7ETV8|E7ETV8_HUMAN,tr|C9JQT6|C9JQT6_HUMAN,tr|C9JZD8|C9JZD8_HUMAN,tr|E7EWK4|E7EWK4_HUMAN,tr|E7EV12|E7EV12_HUMAN,tr|E7EX05|E7EX05_HUMAN,tr|H0Y8C6|H0Y8C6_HUMAN,tr|E7EQT5|E7EQT5_HUMAN,tr|E7ESZ1|E7ESZ1_HUMAN" 11 961.4465 0.97 75058 3323 2 961.44399 481.7305 Importin-5 OS=Homo sapiens OX=9606 GN=IPO5 PE=1 SV=4 4.53 1293.3 - 561581 - - - -2.5982 - 1.889 0.331 - 384.3 1 2 0 -0.0025 9 0 0 0 1.07E+08 1.10E+08 - - - 3.3251 0.8963 221125_WJC_METTL3_EV_vs_WT_F06.03339.03339.2 1.08 14-Jun K.AQEEPPAK.L "sp|Q9UKV3|ACINU_HUMAN,tr|G3V3B0|G3V3B0_HUMAN,tr|S4R3H4|S4R3H4_HUMAN,tr|E7EQT4|E7EQT4_HUMAN" 4 868.429 2.15 75065 3339 2 868.42535 435.2218 Apoptotic chromatin condensation inducer in the nucleus OS=Homo sapiens OX=9606 GN=ACIN1 PE=1 SV=2 4.53 1295.3 - 4.40E+06 - - - -4.2571 - 1.297 0.106 - 158.1 1 2 0 -0.0037 8 0 0 0 3.86E+08 1.80E+08 - - - 0.6071 0.998 221125_WJC_METTL3_EV_vs_WT_F06.03341.03341.2 0.011 14-Jul K.AVC[160.03]GQC[160.03]ER[166.11].A "sp|O15304|SIVA_HUMAN,tr|B4DTY2|B4DTY2_HUMAN,tr|G3V439|G3V439_HUMAN,tr|G3V3U1|G3V3U1_HUMAN,tr|H0YJN1|H0YJN1_HUMAN" 5 988.4094 1.27 75066 3341 2 988.411547 495.212 Apoptosis regulatory protein Siva OS=Homo sapiens OX=9606 GN=SIVA1 PE=1 SV=2 6.03 1295.6 - 2.24E+06 - - - 2.1671 - 1.316 0.371 - 166.5 1 2 0 0.0021 8 0 0 0 8.79E+07 6.93E+07 - - - 2.6087 0.9894 221125_WJC_METTL3_EV_vs_WT_F06.03345.03345.2 0.00209 12-Sep K.NNAVEDR.K "sp|Q92879|CELF1_HUMAN,tr|G5EA30|G5EA30_HUMAN" 2 816.3726 1.15 75068 3345 2 816.369304 409.1936 CUGBP Elav-like family member 1 OS=Homo sapiens OX=9606 GN=CELF1 PE=1 SV=2 4.37 1296.1 - 1.73E+07 - - - -4.0312 - 1.89 0.164 - 676.4 1 2 0 -0.0033 7 0 0 0 3.29E+08 2.86E+08 - - - 2.2683 0.9968 221125_WJC_METTL3_EV_vs_WT_F06.03346.03346.2 0.0484 12-May K.C[160.03]STGYEK.N sp|P49790|NU153_HUMAN 1 843.3433 1.3 75069 3346 2 843.340846 422.6789 Nuclear pore complex protein Nup153 OS=Homo sapiens OX=9606 GN=NUP153 PE=1 SV=2 5.99 1296.1 - 2.29E+06 - - - -2.8731 - 1.182 0.407 - 95.8 1 2 0 -0.0024 7 0 0 0 1.94E+08 1.49E+08 - - - 2.5761 0.8349 221125_WJC_METTL3_EV_vs_WT_F06.03347.03347.2 0.0397 12-May K.NNAVEDR[166.11].K "sp|Q92879|CELF1_HUMAN,tr|G5EA30|G5EA30_HUMAN" 2 826.3809 1.13 75070 3347 2 826.377082 414.1977 CUGBP Elav-like family member 1 OS=Homo sapiens OX=9606 GN=CELF1 PE=1 SV=2 4.37 1296.2 - 1.27E+07 - - - -4.5778 - 1.536 0.001 - 158.9 1 2 0 -0.0038 7 0 0 0 3.43E+08 3.04E+08 - - - 0.4071 0.9965 221125_WJC_METTL3_EV_vs_WT_F06.03352.03352.2 0.111 14-Aug K.AVC[160.03]GQC[160.03]ER.A "sp|O15304|SIVA_HUMAN,tr|B4DTY2|B4DTY2_HUMAN,tr|G3V439|G3V439_HUMAN,tr|G3V3U1|G3V3U1_HUMAN,tr|H0YJN1|H0YJN1_HUMAN" 5 978.4011 1.27 75073 3352 2 978.397682 490.2078 Apoptosis regulatory protein Siva OS=Homo sapiens OX=9606 GN=SIVA1 PE=1 SV=2 6.03 1296.8 - 2.74E+06 - - - -3.5292 - 1.648 0.327 - 284.1 1 2 0 -0.0035 8 0 0 0 8.67E+07 6.84E+07 - - - 2.9618 0.9445 221125_WJC_METTL3_EV_vs_WT_F06.03354.03354.2 3.25 14-Jun K.AQEEPPAK[136.11].L "sp|Q9UKV3|ACINU_HUMAN,tr|G3V3B0|G3V3B0_HUMAN,tr|S4R3H4|S4R3H4_HUMAN,tr|E7EQT4|E7EQT4_HUMAN" 4 876.4432 2.35 75074 3354 2 876.440098 439.2289 Apoptotic chromatin condensation inducer in the nucleus OS=Homo sapiens OX=9606 GN=ACIN1 PE=1 SV=2 4.53 1297 - 6.95E+06 - - - -3.5929 - 1.24 0.142 - 158.1 1 2 0 -0.0031 8 0 0 0 4.68E+08 1.99E+08 - - - 0.7376 0.9989 221125_WJC_METTL3_EV_vs_WT_F06.03356.03356.2 0.000845 14-Oct R.SGGYGGDR.S "sp|Q92804|RBP56_HUMAN,tr|A0A075B7C1|A0A075B7C1_HUMAN,tr|A0A075B7F4|A0A075B7F4_HUMAN" 3 767.3198 1.07 75075 3356 2 767.317865 384.6672 TATA-binding protein-associated factor 2N OS=Homo sapiens OX=9606 GN=TAF15 PE=1 SV=1 5.55 1297.2 - 7.15E+06 - - - -2.5622 - 1.749 0.361 - 510.4 1 2 0 -0.002 8 0 0 0 3.97E+08 3.71E+08 - - - 3.3928 0.7788 221125_WJC_METTL3_EV_vs_WT_F06.03360.03360.2 6.14 12-May R.ILDSNK[136.11]R[166.11].V "sp|Q92973|TNPO1_HUMAN,tr|A0A7P0T9C0|A0A7P0T9C0_HUMAN,tr|A0A7P0TBF0|A0A7P0TBF0_HUMAN,tr|A0A7P0T944|A0A7P0T944_HUMAN,tr|A0A7P0Z4D3|A0A7P0Z4D3_HUMAN" 5 862.4991 0.66 75077 3360 2 862.495595 432.2568 Transportin-1 OS=Homo sapiens OX=9606 GN=TNPO1 PE=1 SV=2 8.75 1297.7 - 1.55E+06 - - - -4.1055 - 1.107 0.08 - 60.6 1 2 0 -0.0035 7 0 0 0 2.00E+07 3.03E+07 - - - -0.0471 0.8335 221125_WJC_METTL3_EV_vs_WT_F06.03364.03364.2 0.155 12-Jun R.LNQTLK[136.11]K[136.11].G "sp|O95757|HS74L_HUMAN,tr|E9PDE8|E9PDE8_HUMAN" 2 859.5462 0.12 75078 3364 2 859.540959 430.7804 Heat shock 70 kDa protein 4L OS=Homo sapiens OX=9606 GN=HSPA4L PE=1 SV=3 10 1298.2 - 1.68E+06 - - - -6.0997 - 1.199 0.206 - 77.9 1 2 0 -0.0052 7 0 0 0 4.35E+06 3.60E+07 - - - 1.1359 0.8077 221125_WJC_METTL3_EV_vs_WT_F06.03366.03366.2 0.000684 14-Aug K.ASDADR[166.11]PC[160.03].R "sp|Q86U44|MTA70_HUMAN,tr|H0YFV6|H0YFV6_HUMAN" 2 900.3635 0.02 75080 3366 2 900.359057 451.189 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 4.21 1298.4 - 1.29E+07 - - - -4.9347 - 1.649 0.465 - 375.3 1 1 0 -0.0044 8 0 0 0 6.11E+06 3.21E+08 - - - 3.9826 0.9994 221125_WJC_METTL3_EV_vs_WT_F06.03378.03378.2 0.000243 16-Oct K.VDEAQADGK[136.11].E sp|Q4VC05|BCL7A_HUMAN 1 939.4389 1.51 75087 3378 2 939.436097 470.7267 B-cell CLL\lymphoma 7 protein family member A OS=Homo sapiens OX=9606 GN=BCL7A PE=1 SV=1 4.03 1299.7 - 1.09E+06 - - - -2.9731 - 2.056 0.478 - 302.5 1 2 0 -0.0028 9 0 0 0 5.94E+07 3.93E+07 - - - 4.6558 0.9935 221125_WJC_METTL3_EV_vs_WT_F06.03384.03384.2 0.0133 14-Jul K.VDNPDSEK[136.11].L sp|Q7Z3B4|NUP54_HUMAN 1 910.4123 2.09 75091 3384 2 910.408315 456.2134 Nucleoporin p54 OS=Homo sapiens OX=9606 GN=NUP54 PE=1 SV=2 4.03 1300.4 - 2.99E+06 - - - -4.4222 - 1.351 0.413 - 118.4 1 2 0 -0.004 8 0 0 0 8.91E+08 4.26E+08 - - - 2.9975 0.9184 221125_WJC_METTL3_EV_vs_WT_F06.03391.03391.2 0.271 14-May K.IC[160.03]EGSEDK[136.11].E sp|P17482|HXB9_HUMAN 1 944.4001 2.66 75096 3391 2 944.397594 473.2073 Homeobox protein Hox-B9 OS=Homo sapiens OX=9606 GN=HOXB9 PE=1 SV=2 4.14 1301.2 - 352427 - - - -2.6133 - 1.112 0.104 - 62.9 2 2 0 -0.0025 8 0 0 0 8.53E+06 3.20E+06 - - - -0.0059 0.9991 221125_WJC_METTL3_EV_vs_WT_F06.03394.03394.2 5.31E-05 16-Oct K.QGPGPGGPK.G sp|P23246|SFPQ_HUMAN 1 793.4083 0.87 75097 3394 2 793.405559 397.7114 "Splicing factor, proline- and glutamine-rich OS=Homo sapiens OX=9606 GN=SFPQ PE=1 SV=2" 8.75 1301.6 - 2.18E+07 - - - -3.3942 - 1.592 0.553 - 360.5 1 2 0 -0.0027 9 0 0 0 1.25E+09 1.43E+09 - - - 4.4699 0.9843 221125_WJC_METTL3_EV_vs_WT_F06.03396.03396.2 0.394 14-Jun R.SGGYGGDR[166.11].S "sp|Q92804|RBP56_HUMAN,tr|A0A075B7C1|A0A075B7C1_HUMAN,tr|A0A075B7F4|A0A075B7F4_HUMAN" 3 777.3281 1.07 75099 3396 2 777.325408 389.6713 TATA-binding protein-associated factor 2N OS=Homo sapiens OX=9606 GN=TAF15 PE=1 SV=1 5.55 1301.8 - 1.08E+07 - - - -3.4644 - 1.298 0.241 - 165.7 1 2 0 -0.0027 8 0 0 0 3.97E+08 3.71E+08 - - - 1.6068 0.9334 221125_WJC_METTL3_EV_vs_WT_F06.03399.03399.2 0.174 12-Jul K.TNETYGK.L "sp|P01040|CYTA_HUMAN,tr|C9J0E4|C9J0E4_HUMAN" 2 811.3712 7.14 75100 3399 2 811.368302 406.6929 Cystatin-A OS=Homo sapiens OX=9606 GN=CSTA PE=1 SV=1 5.66 1302.2 - 3.49E+07 - - - -3.5693 - 1.491 0.039 - 244.2 1 2 0 -0.0029 7 0 0 0 7.84E+08 1.10E+08 - - - 0.5938 0.951 221125_WJC_METTL3_EV_vs_WT_F06.03406.03406.2 0.258 14-Jun R.VNSPESER.L "sp|Q5TCY1|TTBK1_HUMAN,tr|X6R456|X6R456_HUMAN" 2 916.425 3.27 75104 3406 2 916.420823 459.2198 Tau-tubulin kinase 1 OS=Homo sapiens OX=9606 GN=TTBK1 PE=1 SV=2 4.53 1302.9 - 2.03E+06 - - - -4.5841 - 1.097 0.274 - 102 1 2 0 -0.0042 8 0 0 0 8.47E+07 2.59E+07 - - - 1.3427 0.9969 221125_WJC_METTL3_EV_vs_WT_F06.03420.03420.2 0.0173 16-Aug K.ELASSEQNK[136.11].N "sp|Q92878|RAD50_HUMAN,tr|E7EN38|E7EN38_HUMAN,tr|A0A494C1B7|A0A494C1B7_HUMAN,tr|A0A1W2PQ90|A0A1W2PQ90_HUMAN" 4 1012.4917 0.95 75110 3420 2 1012.488519 507.2531 DNA repair protein RAD50 OS=Homo sapiens OX=9606 GN=RAD50 PE=1 SV=1 4.53 1304.6 - 568224 - - - -3.0963 - 1.659 0.308 - 247 1 2 0 -0.0031 9 0 0 0 1.90E+07 2.01E+07 - - - 2.7794 0.8347 221125_WJC_METTL3_EV_vs_WT_F06.03423.03423.2 0.0189 12-Jul Q.QVDTSTR.T sp|P04264|K2C1_HUMAN 1 805.393 3.17 75111 3423 2 805.391469 403.7038 "Keratin, type II cytoskeletal 1 OS=Homo sapiens OX=9606 GN=KRT1 PE=1 SV=6" 5.84 1305 - 2.19E+07 - - - -1.896 - 1.189 0.32 - 276.5 1 1 0 -0.0015 7 0 0 0 7.14E+08 2.25E+08 - - - 1.9526 0.9992 221125_WJC_METTL3_EV_vs_WT_F06.03425.03425.2 0.0071 18-Nov K.APSGGAVEQK[136.11].V sp|Q14781|CBX2_HUMAN 1 950.4913 2.13 75112 3425 2 950.488328 476.2529 Chromobox protein homolog 2 OS=Homo sapiens OX=9606 GN=CBX2 PE=1 SV=2 6.05 1305.2 - 516443 - - - -3.0847 - 2.116 0.431 - 298.7 1 2 0 -0.0029 10 0 0 0 8.81E+07 4.13E+07 - - - 4.3156 0.9993 221125_WJC_METTL3_EV_vs_WT_F06.03427.03427.2 9.78E-05 18-Nov K.APSGGAVEQK.V sp|Q14781|CBX2_HUMAN 1 942.4771 2.17 75113 3427 2 942.474579 472.2458 Chromobox protein homolog 2 OS=Homo sapiens OX=9606 GN=CBX2 PE=1 SV=2 6.05 1305.6 - 1.26E+06 - - - -2.6324 - 1.923 0.435 - 288.7 1 2 0 -0.0025 10 0 0 0 8.94E+07 4.13E+07 - - - 4.0783 0.9984 221125_WJC_METTL3_EV_vs_WT_F06.03430.03430.2 0.000804 16-Jul K.QGPGPGGPK[136.11].G sp|P23246|SFPQ_HUMAN 1 801.4225 0.89 75114 3430 2 801.420451 401.7185 "Splicing factor, proline- and glutamine-rich OS=Homo sapiens OX=9606 GN=SFPQ PE=1 SV=2" 8.75 1306 - 3.03E+07 - - - -2.4968 - 1.393 0.402 - 164.1 1 2 0 -0.002 9 0 0 0 1.24E+09 1.39E+09 - - - 2.9685 0.9968 221125_WJC_METTL3_EV_vs_WT_F06.03431.03431.2 0.00061 14-Sep R.LASC[160.03]SDDR.T sp|O76071|CIAO1_HUMAN 1 922.3814 0.89 75115 3431 2 922.376884 462.198 Probable cytosolic iron-sulfur protein assembly protein CIAO1 OS=Homo sapiens OX=9606 GN=CIAO1 PE=1 SV=1 4.21 1306 - 2.79E+06 - - - -4.9448 - 1.912 0.448 - 294.6 1 2 0 -0.0046 8 0 0 0 4.64E+07 5.22E+07 - - - 4.3033 0.9619 221125_WJC_METTL3_EV_vs_WT_F06.03436.03436.2 0.26 14-Oct K.SLGTNQTK.E sp|Q9UPV0|CE164_HUMAN 1 847.4399 1.51 75120 3436 2 847.435966 424.7272 Centrosomal protein of 164 kDa OS=Homo sapiens OX=9606 GN=CEP164 PE=1 SV=3 8.47 1306.4 - 983825 - - - -4.6965 - 1.415 0.205 - 268.6 1 2 0 -0.004 8 0 0 0 5.23E+07 3.46E+07 - - - 1.6008 0.9989 221125_WJC_METTL3_EV_vs_WT_F06.03440.03440.2 0.0421 16-Oct R.SGGGYGGDR[166.11].S "sp|Q92804|RBP56_HUMAN,sp|Q92804|RBP56_HUMAN,sp|Q92804|RBP56_HUMAN,sp|Q92804|RBP56_HUMAN,tr|A0A075B7C1|A0A075B7C1_HUMAN,tr|A0A075B7F4|A0A075B7F4_HUMAN,tr|A0A075B7F4|A0A075B7F4_HUMAN" 7 834.3496 1.01 75122 3440 2 834.346423 418.1821 TATA-binding protein-associated factor 2N OS=Homo sapiens OX=9606 GN=TAF15 PE=1 SV=1 5.55 1306.9 - 1.19E+07 - - - -3.7658 - 2.253 0.44 - 507.8 1 2 0 -0.0031 9 0 0 0 7.29E+08 7.23E+08 - - - 4.6398 0.9958 221125_WJC_METTL3_EV_vs_WT_F06.03441.03441.2 0.00832 16-Oct R.SGGGYGGDR.S "sp|Q92804|RBP56_HUMAN,sp|Q92804|RBP56_HUMAN,sp|Q92804|RBP56_HUMAN,sp|Q92804|RBP56_HUMAN,tr|A0A075B7C1|A0A075B7C1_HUMAN,tr|A0A075B7F4|A0A075B7F4_HUMAN,tr|A0A075B7F4|A0A075B7F4_HUMAN" 7 824.3413 1.01 75123 3441 2 824.338581 413.1779 TATA-binding protein-associated factor 2N OS=Homo sapiens OX=9606 GN=TAF15 PE=1 SV=1 5.55 1307 - 9.83E+06 - - - -3.2911 - 1.864 0.242 - 481.8 1 2 0 -0.0027 9 0 0 0 7.29E+08 7.23E+08 - - - 2.6291 0.8734 221125_WJC_METTL3_EV_vs_WT_F06.03445.03445.2 0.0165 18-Oct A.LGGNSSPSAK.D sp|P05387|RLA2_HUMAN 1 916.4614 0.95 75125 3445 2 916.458303 459.238 60S acidic ribosomal protein P2 OS=Homo sapiens OX=9606 GN=RPLP2 PE=1 SV=1 8.75 1307.4 - 1.68E+06 - - - -3.3902 - 1.748 0.358 - 216.8 1 1 0 -0.0031 10 0 0 0 5.84E+07 6.13E+07 - - - 3.2431 0.9921 221125_WJC_METTL3_EV_vs_WT_F06.03450.03450.2 0.0399 12-Aug K.C[160.03]PAPC[160.03]QR.T sp|Q5T750|XP32_HUMAN 1 887.3742 13.69 75129 3450 2 887.371032 444.6944 Skin-specific protein 32 OS=Homo sapiens OX=9606 GN=XP32 PE=1 SV=1 8.07 1307.8 - 6.45E+06 - - - -3.5611 - 1.559 0.241 - 381.8 1 2 0 -0.0032 7 0 0 0 3.08E+08 2.25E+07 - - - 2.227 0.9306 221125_WJC_METTL3_EV_vs_WT_F06.03451.03451.2 0.817 12-Jun R.DQNGLSK[136.11].G sp|Q13151|ROA0_HUMAN 1 768.3857 1.05 75130 3451 2 768.383325 385.2001 Heterogeneous nuclear ribonucleoprotein A0 OS=Homo sapiens OX=9606 GN=HNRNPA0 PE=1 SV=1 5.84 1307.9 - 3.90E+06 - - - -3.1325 - 1.292 0.068 - 236.9 1 2 0 -0.0024 7 0 0 0 1.52E+09 1.45E+09 - - - 0.3542 0.9911 221125_WJC_METTL3_EV_vs_WT_F06.03456.03456.2 0.0675 14-Jun R.ESSSASLK[136.11].S "sp|Q8IZH2|XRN1_HUMAN,tr|H7C5E4|H7C5E4_HUMAN" 2 815.4116 1.55 75132 3456 2 815.409501 408.7131 5'-3' exoribonuclease 1 OS=Homo sapiens OX=9606 GN=XRN1 PE=1 SV=1 6.1 1308.5 - 6.05E+06 - - - -2.5889 - 1.441 0.21 - 160.5 2 2 0 -0.0021 8 0 0 0 3.55E+08 2.28E+08 - - - 1.5588 0.7859 221125_WJC_METTL3_EV_vs_WT_F06.03457.03457.2 0.00571 18-Nov A.LGGNSSPSAK[136.11].D sp|P05387|RLA2_HUMAN 1 924.4756 0.95 75133 3457 2 924.472133 463.2451 60S acidic ribosomal protein P2 OS=Homo sapiens OX=9606 GN=RPLP2 PE=1 SV=1 8.75 1308.5 - 2.88E+06 - - - -3.7611 - 1.783 0.301 - 202.1 1 1 0 -0.0035 10 0 0 0 5.87E+07 6.16E+07 - - - 2.8773 0.8395 221125_WJC_METTL3_EV_vs_WT_F06.03478.03478.2 0.283 16-Jul K.SSTAAQEVK.T sp|Q9P258|RCC2_HUMAN 1 919.4611 0.48 75143 3478 2 919.45753 460.7378 Protein RCC2 OS=Homo sapiens OX=9606 GN=RCC2 PE=1 SV=2 5.72 1310.9 - 3.42E+06 - - - -3.8555 - 1.458 0.023 - 130.4 3 2 0 -0.0035 9 0 0 0 1.55E+08 3.20E+08 - - - 0.0875 0.9989 221125_WJC_METTL3_EV_vs_WT_F06.03479.03479.2 0.0013 14-Aug K.QSDTMTEK[136.11].E "sp|Q15643|TRIPB_HUMAN,tr|H0YJ97|H0YJ97_HUMAN" 2 946.4157 1.17 75144 3479 2 946.413811 474.2151 Thyroid receptor-interacting protein 11 OS=Homo sapiens OX=9606 GN=TRIP11 PE=1 SV=3 4.37 1311 - 1.72E+06 - - - -2.0086 - 1.531 0.36 - 355.2 1 2 0 -0.0019 8 0 0 0 2.27E+08 1.93E+08 - - - 2.9839 0.9925 221125_WJC_METTL3_EV_vs_WT_F06.03488.03488.2 1.66 12-Jun K.IQAQEDR.E "sp|Q9Y3D7|TIM16_HUMAN,tr|I3L3T0|I3L3T0_HUMAN,tr|A0A0A6YYL4|A0A0A6YYL4_HUMAN,tr|I3L0X9|I3L0X9_HUMAN" 4 858.4195 0.66 75149 3488 2 858.417809 430.217 Mitochondrial import inner membrane translocase subunit TIM16 OS=Homo sapiens OX=9606 GN=PAM16 PE=1 SV=2 4.37 1311.9 - 4.77E+06 - - - -2.0223 - 1.482 0.148 - 119.8 1 2 0 -0.0017 7 0 0 0 5.82E+08 8.85E+08 - - - 1.3801 0.9644 221125_WJC_METTL3_EV_vs_WT_F06.03496.03496.2 0.166 12-Jun K.LHTVQPK.G "sp|P55036|PSMD4_HUMAN,sp|A2A3N6|PIPSL_HUMAN,tr|A6PVX3|A6PVX3_HUMAN,tr|Q5VWC4|Q5VWC4_HUMAN" 4 821.4759 0.94 75154 3496 2 821.47243 411.7452 26S proteasome non-ATPase regulatory subunit 4 OS=Homo sapiens OX=9606 GN=PSMD4 PE=1 SV=1 8.76 1312.8 - 1.16E+07 - - - -4.2704 - 1.361 0.19 - 203.9 1 2 0 -0.0035 7 0 0 0 2.37E+08 2.52E+08 - - - 1.4198 0.9557 221125_WJC_METTL3_EV_vs_WT_F06.03501.03501.2 0.0702 14-May K.QSDTMTEK.E "sp|Q15643|TRIPB_HUMAN,tr|H0YJ97|H0YJ97_HUMAN" 2 938.4015 1.17 75157 3501 2 938.398415 470.208 Thyroid receptor-interacting protein 11 OS=Homo sapiens OX=9606 GN=TRIP11 PE=1 SV=3 4.37 1313.3 - 9.61E+06 - - - -3.3003 - 1.125 0.202 - 108.7 2 2 0 -0.0031 8 0 0 0 2.27E+08 1.93E+08 - - - 0.7528 0.9982 221125_WJC_METTL3_EV_vs_WT_F06.03507.03507.2 0.312 14-Aug R.TEAANVEK.L sp|Q92900|RENT1_HUMAN 1 860.424 0.62 75159 3507 2 860.424338 431.2193 Regulator of nonsense transcripts 1 OS=Homo sapiens OX=9606 GN=UPF1 PE=1 SV=2 4.53 1314.1 - 9.39E+06 - - - 0.437 - 1.506 0.223 - 184.6 1 2 0 0.0004 8 0 0 0 4.67E+08 7.51E+08 - - - 1.9229 0.9988 221125_WJC_METTL3_EV_vs_WT_F06.03509.03509.2 0.00264 14-Aug K.AQAYQTGK[136.11].G "sp|Q58FF3|ENPLL_HUMAN,sp|P14625|ENPL_HUMAN,tr|A0A7P0T917|A0A7P0T917_HUMAN,tr|A0A7P0T823|A0A7P0T823_HUMAN,tr|A0A7P0TAE1|A0A7P0TAE1_HUMAN,tr|H0YIV0|H0YIV0_HUMAN,tr|A0A087WT78|A0A087WT78_HUMAN,tr|A0A7P0TAT8|A0A7P0TAT8_HUMAN" 8 873.4436 1.2 75160 3509 2 873.441279 437.7291 Putative endoplasmin-like protein OS=Homo sapiens OX=9606 GN=HSP90B2P PE=5 SV=1 8.63 1314.3 - 6.83E+06 - - - -2.6355 - 1.601 0.395 - 347.7 1 2 0 -0.0023 8 0 0 0 2.26E+08 1.87E+08 - - - 3.3771 0.9915 221125_WJC_METTL3_EV_vs_WT_F06.03513.03513.2 0.0122 12-Jul K.NNAQSIR[166.11].A sp|Q9BVP2|GNL3_HUMAN 1 811.4176 1.89 75161 3513 2 811.414153 406.7161 Guanine nucleotide-binding protein-like 3 OS=Homo sapiens OX=9606 GN=GNL3 PE=1 SV=2 9.75 1314.8 - 1.05E+07 - - - -4.2284 - 1.501 0.307 - 349 1 2 0 -0.0034 7 0 0 0 6.68E+08 3.54E+08 - - - 2.5943 0.9988 221125_WJC_METTL3_EV_vs_WT_F06.03529.03529.2 3.38E-05 18-Aug K.ADGAEAK[136.11]PAE.- sp|P35579|MYH9_HUMAN 1 965.4545 0.92 75172 3529 2 965.451249 483.7345 Myosin-9 OS=Homo sapiens OX=9606 GN=MYH9 PE=1 SV=4 4.43 1316.6 - 872288 - - - -3.4088 - 1.682 0.489 - 217.3 1 2 0 -0.0033 10 0 0 0 1.31E+08 1.43E+08 - - - 4.1032 0.9993 221125_WJC_METTL3_EV_vs_WT_F06.03538.03538.2 0.0617 18-Oct K.ADGAEAKPAE.- sp|P35579|MYH9_HUMAN 1 957.4403 0.9 75178 3538 2 957.439466 479.7274 Myosin-9 OS=Homo sapiens OX=9606 GN=MYH9 PE=1 SV=4 4.43 1317.5 - 1.85E+06 - - - -0.9129 - 1.56 0.353 - 211.6 1 2 0 -0.0009 10 0 0 0 1.27E+08 1.42E+08 - - - 2.8892 0.9865 221125_WJC_METTL3_EV_vs_WT_F06.03553.03553.2 0.196 14-Jul K.QSPASPER.D "sp|P13646|K1C13_HUMAN,tr|K7EMD9|K7EMD9_HUMAN,tr|K7ERE3|K7ERE3_HUMAN" 3 870.4195 7.14 75187 3553 2 870.415938 436.217 "Keratin, type I cytoskeletal 13 OS=Homo sapiens OX=9606 GN=KRT13 PE=1 SV=4" 6 1319.1 - 8.58E+06 - - - -4.144 - 1.557 0.238 - 270.3 1 2 0 -0.0036 8 0 0 0 3.60E+08 5.04E+07 - - - 2.1331 0.9967 221125_WJC_METTL3_EV_vs_WT_F06.03558.03558.2 0.00912 14-Aug R.IAESNHIK[136.11].L "sp|O43707|ACTN4_HUMAN,tr|F5GXS2|F5GXS2_HUMAN,tr|H7C144|H7C144_HUMAN" 3 918.5014 1.62 75189 3558 2 918.49853 460.258 Alpha-actinin-4 OS=Homo sapiens OX=9606 GN=ACTN4 PE=1 SV=2 6.75 1319.7 - 1.36E+06 - - - -3.1573 - 1.582 0.317 - 143.4 1 2 0 -0.0029 8 0 0 0 9.45E+07 5.84E+07 - - - 2.7648 0.9915 221125_WJC_METTL3_EV_vs_WT_F06.03562.03562.2 2.23 12-Sep K.C[160.03]ISEDQK[136.11].Y "sp|Q9NX58|LYAR_HUMAN,tr|D6RDJ1|D6RDJ1_HUMAN" 2 886.3946 0.58 75191 3562 2 886.391881 444.2046 Cell growth-regulating nucleolar protein OS=Homo sapiens OX=9606 GN=LYAR PE=1 SV=2 4.37 1320.2 - 6.02E+06 - - - -3.0472 - 1.441 0.224 - 285.8 1 2 0 -0.0027 7 0 0 0 7.60E+07 1.30E+08 - - - 1.8522 0.9967 221125_WJC_METTL3_EV_vs_WT_F06.03572.03572.2 0.0516 14-Aug R.TTDGSLQK.K tr|A0A087WXC0|A0A087WXC0_HUMAN 1 848.424 0.66 75195 3572 2 848.422305 425.2193 Synaptic functional regulator FMR1 (Fragment) OS=Homo sapiens OX=9606 GN=FMR1 PE=1 SV=1 5.5 1321.5 - 3.58E+06 - - - -1.953 - 1.287 0.296 - 264.9 1 2 0 -0.0017 8 0 0 0 7.11E+07 1.07E+08 - - - 1.9877 0.9649 221125_WJC_METTL3_EV_vs_WT_F06.03578.03578.2 0.341 16-Jul K.ASEPAGGPR.R "sp|Q8WWM7|ATX2L_HUMAN,tr|H3BSQ5|H3BSQ5_HUMAN,tr|H3BSK9|H3BSK9_HUMAN,tr|H3BUE3|H3BUE3_HUMAN,tr|H3BUF6|H3BUF6_HUMAN" 5 840.409 1.06 75199 3578 2 840.40582 421.2118 Ataxin-2-like protein OS=Homo sapiens OX=9606 GN=ATXN2L PE=1 SV=2 6.05 1322.2 - 1.61E+06 - - - -3.7601 - 1.248 0.2 - 218.6 1 2 0 -0.0032 9 0 0 0 6.21E+08 5.84E+08 - - - 1.1581 0.9976 221125_WJC_METTL3_EV_vs_WT_F06.03580.03580.2 0.00582 16-Aug K.IQSC[160.03]NSGVK.S "sp|Q92576|PHF3_HUMAN,tr|E9PE34|E9PE34_HUMAN,tr|E7EVH3|E7EVH3_HUMAN,tr|D6R9X2|D6R9X2_HUMAN,tr|A0A1B0GX99|A0A1B0GX99_HUMAN" 5 991.4757 0.73 75201 3580 2 991.472926 496.7451 PHD finger protein 3 OS=Homo sapiens OX=9606 GN=PHF3 PE=1 SV=3 8.22 1322.3 - 886072 - - - -2.7777 - 1.508 0.348 - 108 1 2 0 -0.0028 9 0 0 0 2.91E+08 3.99E+08 - - - 2.7989 0.9893 221125_WJC_METTL3_EV_vs_WT_F06.03586.03586.2 0.1 12-Jul R.QQEVEER[166.11].Q "sp|Q9BUQ8|DDX23_HUMAN,tr|H0YIL9|H0YIL9_HUMAN" 2 926.4333 1.38 75205 3586 2 926.429145 464.2239 Probable ATP-dependent RNA helicase DDX23 OS=Homo sapiens OX=9606 GN=DDX23 PE=1 SV=3 4.25 1322.9 - 923003 - - - -4.4785 - 1.468 0.311 - 400.4 1 2 0 -0.0041 7 0 0 0 5.89E+07 4.27E+07 - - - 2.5532 0.9155 221125_WJC_METTL3_EV_vs_WT_F06.03592.03592.2 0.224 14-Jul L.AAQDVAQR.C "sp|P62263|RS14_HUMAN,tr|A0A2R8Y811|A0A2R8Y811_HUMAN,tr|E5RH77|E5RH77_HUMAN" 3 857.4355 2.77 75209 3592 2 857.436371 429.725 40S ribosomal protein S14 OS=Homo sapiens OX=9606 GN=RPS14 PE=1 SV=3 5.88 1323.5 - 2.19E+06 - - - 0.982 - 1.633 0.232 - 291.7 1 1 0 0.0008 8 0 0 0 3.95E+08 1.43E+08 - - - 2.2334 0.9003 221125_WJC_METTL3_EV_vs_WT_F06.03603.03603.2 0.25 14-Aug L.AAQDVAQR[166.11].C "sp|P62263|RS14_HUMAN,tr|A0A2R8Y811|A0A2R8Y811_HUMAN,tr|E5RH77|E5RH77_HUMAN" 3 867.4438 2.76 75212 3603 2 867.442188 434.7292 40S ribosomal protein S14 OS=Homo sapiens OX=9606 GN=RPS14 PE=1 SV=3 5.88 1325.1 - 7.25E+06 - - - -1.8572 - 1.624 0.26 - 389.7 1 1 0 -0.0016 8 0 0 0 3.95E+08 1.43E+08 - - - 2.4233 0.9998 221125_WJC_METTL3_EV_vs_WT_F06.03606.03606.2 0.000468 18-Oct K.SLSSTSAGGK.K "sp|Q6W2J9|BCOR_HUMAN,tr|H7BZ37|H7BZ37_HUMAN,tr|H7C2V9|H7C2V9_HUMAN,tr|H7BYY2|H7BYY2_HUMAN,tr|H7C231|H7C231_HUMAN" 5 893.4454 1.59 75215 3606 2 893.444711 447.73 BCL-6 corepressor OS=Homo sapiens OX=9606 GN=BCOR PE=1 SV=1 8.47 1325.3 - 3.09E+06 - - - -0.7992 - 1.742 0.498 - 224.6 1 2 0 -0.0007 10 0 0 0 1.24E+08 7.82E+07 - - - 4.2683 0.9949 221125_WJC_METTL3_EV_vs_WT_F06.03614.03614.2 0.271 14-Nov R.EIANSNER[166.11].R sp|Q01664|TFAP4_HUMAN 1 941.4442 2.24 75220 3614 2 941.442531 471.7294 Transcription factor AP-4 OS=Homo sapiens OX=9606 GN=TFAP4 PE=1 SV=2 4.53 1326.1 - 3.67E+06 - - - -1.7654 - 1.284 0.235 - 548.2 1 2 0 -0.0017 8 0 0 0 3.47E+08 1.55E+08 - - - 1.5301 0.9773 221125_WJC_METTL3_EV_vs_WT_F06.03622.03622.2 0.0491 14-Aug K.QALSQAQK[136.11].S "sp|P82094|TMF1_HUMAN,tr|F8WF45|F8WF45_HUMAN,tr|A0A2R8Y7M0|A0A2R8Y7M0_HUMAN" 3 880.4858 1.43 75226 3622 2 880.481889 441.2502 TATA element modulatory factor OS=Homo sapiens OX=9606 GN=TMF1 PE=1 SV=2 8.75 1327 - 7.37E+06 - - - -4.4192 - 1.577 0.196 - 213.4 1 2 0 -0.0039 8 0 0 0 5.14E+08 3.58E+08 - - - 1.8613 0.9325 221125_WJC_METTL3_EV_vs_WT_F06.03629.03629.2 2.05 12-Jun K.LTPQGQR[166.11].D "sp|P39019|RS19_HUMAN,tr|A0A075B6E2|A0A075B6E2_HUMAN" 2 808.4431 0.7 75232 3629 2 808.441253 405.2288 40S ribosomal protein S19 OS=Homo sapiens OX=9606 GN=RPS19 PE=1 SV=2 9.75 1327.8 - 8.66E+06 - - - -2.2488 - 1.166 0.058 - 184.2 1 2 0 -0.0018 7 0 0 0 8.55E+07 1.22E+08 - - - -0.0446 0.9055 221125_WJC_METTL3_EV_vs_WT_F06.03631.03631.2 2.53 12-Apr R.QYGSEGR.F "sp|Q7Z7H5|TMED4_HUMAN,sp|Q9BVK6|TMED9_HUMAN,tr|F8W7F7|F8W7F7_HUMAN" 3 795.3511 1.43 75233 3631 2 795.349293 398.6828 Transmembrane emp24 domain-containing protein 4 OS=Homo sapiens OX=9606 GN=TMED4 PE=1 SV=1 6 1328 - 9.71E+06 - - - -2.3109 - 0.997 0.098 - 92.8 1 2 0 -0.0018 7 0 0 0 1.37E+08 9.59E+07 - - - -0.2453 0.9104 221125_WJC_METTL3_EV_vs_WT_F06.03632.03632.2 9.56 16-Jun K.SLGVGFATR.Q "sp|P05413|FABPH_HUMAN,tr|S4R3A2|S4R3A2_HUMAN,tr|S4R371|S4R371_HUMAN" 3 906.4923 0.46 75234 3632 2 906.490698 454.2534 "Fatty acid-binding protein, heart OS=Homo sapiens OX=9606 GN=FABP3 PE=1 SV=4" 9.47 1328.1 - 1.63E+06 - - - -1.7849 - 1.425 0.001 - 101.1 14 2 0 -0.0016 9 0 0 0 2.57E+07 5.61E+07 - - - -0.4395 0.879 221125_WJC_METTL3_EV_vs_WT_F06.03637.03637.2 0.37 12-Jul K.AVQQVQR.L "sp|Q9Y244|POMP_HUMAN,tr|A0A1W2PS02|A0A1W2PS02_HUMAN" 2 827.4614 1.55 75237 3637 2 827.45902 414.738 Proteasome maturation protein OS=Homo sapiens OX=9606 GN=POMP PE=1 SV=1 9.79 1328.7 - 1.06E+07 - - - -2.8158 - 1.273 0.001 - 241.4 1 2 0 -0.0023 7 0 0 0 3.12E+08 2.02E+08 - - - -0.1875 0.9989 221125_WJC_METTL3_EV_vs_WT_F06.03639.03639.2 0.00759 18-Nov K.TAEAGGVTGK[136.11].G "sp|P09874|PARP1_HUMAN,tr|A0A7I2V5E9|A0A7I2V5E9_HUMAN,tr|A0A7I2V625|A0A7I2V625_HUMAN,tr|A0A7I2V3E1|A0A7I2V3E1_HUMAN" 4 897.4647 1.01 75239 3639 2 897.461776 449.7396 Poly [ADP-ribose] polymerase 1 OS=Homo sapiens OX=9606 GN=PARP1 PE=1 SV=4 5.66 1328.8 - 8.61E+06 - - - -3.2703 - 2.077 0.413 - 407.8 1 2 0 -0.0029 10 0 0 0 1.21E+09 1.20E+09 - - - 4.1307 0.999 221125_WJC_METTL3_EV_vs_WT_F06.03646.03646.2 0.00283 16-Sep R.LANSEANTR.R sp|Q9H8W4|PKHF2_HUMAN 1 974.4781 0.9 75244 3646 2 974.475103 488.2463 Pleckstrin homology domain-containing family F member 2 OS=Homo sapiens OX=9606 GN=PLEKHF2 PE=1 SV=1 6 1329.5 - 1.39E+06 - - - -3.0981 - 2.003 0.405 - 237.1 1 2 0 -0.003 9 0 0 0 5.80E+07 6.47E+07 - - - 4.041 0.9893 221125_WJC_METTL3_EV_vs_WT_F06.03651.03651.2 0.184 12-Jul K.AEDEVQR[166.11].E "sp|P0DMV8|HS71A_HUMAN,sp|P34931|HS71L_HUMAN,sp|P0DMV9|HS71B_HUMAN,tr|Q53FA3|Q53FA3_HUMAN,tr|V9GZ37|V9GZ37_HUMAN,tr|A0A0G2JIW1|A0A0G2JIW1_HUMAN" 6 855.3962 0.14 75247 3651 2 855.393 428.7054 Heat shock 70 kDa protein 1A OS=Homo sapiens OX=9606 GN=HSPA1A PE=1 SV=1 4.14 1330.2 - 1.51E+07 - - - -3.7176 - 1.53 0.228 - 271.6 1 2 0 -0.0032 7 0 0 0 5.71E+08 3.96E+09 - - - 2.0715 0.9951 221125_WJC_METTL3_EV_vs_WT_F06.03652.03652.2 0.0129 12-Aug R.GHVQPIR.C "sp|Q5JNZ5|RS26L_HUMAN,sp|P62854|RS26_HUMAN" 2 805.4559 0.93 75248 3652 2 805.452501 403.7352 Putative 40S ribosomal protein S26-like 1 OS=Homo sapiens OX=9606 GN=RPS26P11 PE=5 SV=1 9.76 1330.2 - 9.05E+06 - - - -4.184 - 1.67 0.33 - 341.4 1 2 0 -0.0034 7 0 0 0 6.68E+08 7.22E+08 - - - 3.1022 0.9246 221125_WJC_METTL3_EV_vs_WT_F06.03653.03653.2 0.164 12-Jun K.YSAQGER[166.11].Q "sp|O43324|MCA3_HUMAN,tr|C9J1V9|C9J1V9_HUMAN,tr|H0YAL7|H0YAL7_HUMAN,tr|D6RBD7|D6RBD7_HUMAN" 4 819.3751 0.67 75249 3653 2 819.372215 410.6948 Eukaryotic translation elongation factor 1 epsilon-1 OS=Homo sapiens OX=9606 GN=EEF1E1 PE=1 SV=1 6 1330.3 - 9.12E+06 - - - -3.4612 - 1.308 0.076 - 115.3 1 2 0 -0.0028 7 0 0 0 1.24E+08 1.86E+08 - - - 0.4522 0.9968 221125_WJC_METTL3_EV_vs_WT_F06.03656.03656.2 0.00531 14-Jun R.EC[160.03]SDVQPK.L sp|O43678|NDUA2_HUMAN 1 961.4175 2.52 75252 3656 2 961.414896 481.716 NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 2 OS=Homo sapiens OX=9606 GN=NDUFA2 PE=1 SV=3 4.37 1330.4 - 3.21E+06 - - - -2.7043 - 1.182 0.395 - 170.5 1 2 0 -0.0026 8 0 0 0 1.11E+08 4.41E+07 - - - 2.4619 0.9956 221125_WJC_METTL3_EV_vs_WT_F06.03660.03660.2 0.00564 14-Aug R.EC[160.03]SDVQPK[136.11].L sp|O43678|NDUA2_HUMAN 1 969.4317 2.52 75254 3660 2 969.42796 485.7231 NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 2 OS=Homo sapiens OX=9606 GN=NDUFA2 PE=1 SV=3 4.37 1330.9 - 1.43E+06 - - - -3.8538 - 1.263 0.436 - 257.9 1 2 0 -0.0037 8 0 0 0 1.11E+08 4.41E+07 - - - 2.9643 0.9959 221125_WJC_METTL3_EV_vs_WT_F06.03661.03661.2 0.0431 16-Sep R.LEGENTQDK[136.11].N sp|Q7KZF4|SND1_HUMAN 1 1040.4866 0.79 75255 3661 2 1040.482478 521.2506 Staphylococcal nuclease domain-containing protein 1 OS=Homo sapiens OX=9606 GN=SND1 PE=1 SV=1 4.14 1331 - 2.91E+06 - - - -3.9309 - 1.605 0.364 - 209.2 1 2 0 -0.0041 9 0 0 0 6.61E+07 8.39E+07 - - - 3.097 0.998 221125_WJC_METTL3_EV_vs_WT_F06.03662.03662.2 0.0195 16-Sep R.LEGENTQDK.N sp|Q7KZF4|SND1_HUMAN 1 1032.4724 0.79 75256 3662 2 1032.468831 517.2435 Staphylococcal nuclease domain-containing protein 1 OS=Homo sapiens OX=9606 GN=SND1 PE=1 SV=1 4.14 1331.1 - 2.05E+06 - - - -3.4258 - 1.597 0.415 - 208.8 1 2 0 -0.0035 9 0 0 0 6.61E+07 8.39E+07 - - - 3.4594 0.9972 221125_WJC_METTL3_EV_vs_WT_F06.03669.03669.2 1.40E-05 14-Aug R.VGSEC[160.03]PDR[166.11].L "tr|A0A7I2V598|A0A7I2V598_HUMAN,tr|H0Y5F5|H0Y5F5_HUMAN,tr|H0Y6X6|H0Y6X6_HUMAN" 3 928.3948 1.35 75258 3669 2 928.390773 465.2047 Polyadenylate-binding protein OS=Homo sapiens OX=9606 GN=PABPC4 PE=1 SV=1 4.37 1332 - 1.05E+07 - - - -4.3376 - 1.73 0.429 - 244 1 2 0 -0.004 8 0 0 0 2.42E+08 1.79E+08 - - - 3.8614 0.9155 221125_WJC_METTL3_EV_vs_WT_F06.03670.03670.2 0.0825 12-Jun K.YSAQGER.Q "sp|O43324|MCA3_HUMAN,tr|C9J1V9|C9J1V9_HUMAN,tr|H0YAL7|H0YAL7_HUMAN,tr|D6RBD7|D6RBD7_HUMAN" 4 809.3668 0.64 75259 3670 2 809.363942 405.6907 Eukaryotic translation elongation factor 1 epsilon-1 OS=Homo sapiens OX=9606 GN=EEF1E1 PE=1 SV=1 6 1332.1 - 7.27E+06 - - - -3.5077 - 1.101 0.142 - 121.1 1 2 0 -0.0028 7 0 0 0 1.17E+08 1.81E+08 - - - 0.3938 0.9563 221125_WJC_METTL3_EV_vs_WT_F06.03673.03673.2 2.28 14-Aug R.LEQEEQQR.L "sp|Q3ZCQ8|TIM50_HUMAN,tr|M0R0C3|M0R0C3_HUMAN,tr|M0R2F8|M0R2F8_HUMAN" 3 1058.4993 1.13 75262 3673 2 1058.493052 530.2569 Mitochondrial import inner membrane translocase subunit TIM50 OS=Homo sapiens OX=9606 GN=TIMM50 PE=1 SV=2 4.25 1332.4 - 1.13E+06 - - - -5.8573 - 1.721 0.199 - 305.5 1 2 0 -0.0062 8 0 0 0 2.43E+08 2.16E+08 - - - 2.1462 0.9918 221125_WJC_METTL3_EV_vs_WT_F06.03676.03676.2 3.06 14-Sep R.LEQEEQQR[166.11].L "sp|Q3ZCQ8|TIM50_HUMAN,tr|M0R0C3|M0R0C3_HUMAN,tr|M0R2F8|M0R2F8_HUMAN" 3 1068.5075 1.13 75263 3676 2 1068.503186 535.261 Mitochondrial import inner membrane translocase subunit TIM50 OS=Homo sapiens OX=9606 GN=TIMM50 PE=1 SV=2 4.25 1332.8 - 4.32E+06 - - - -4.058 - 1.951 0.197 - 393 1 2 0 -0.0043 8 0 0 0 2.43E+08 2.16E+08 - - - 2.5104 0.9874 221125_WJC_METTL3_EV_vs_WT_F06.03678.03678.2 0.258 12-Jul K.AEDEVQR.E "sp|P0DMV8|HS71A_HUMAN,sp|P34931|HS71L_HUMAN,sp|P0DMV9|HS71B_HUMAN,tr|Q53FA3|Q53FA3_HUMAN,tr|V9GZ37|V9GZ37_HUMAN,tr|A0A0G2JIW1|A0A0G2JIW1_HUMAN" 6 845.3879 0.14 75264 3678 2 845.385017 423.7012 Heat shock 70 kDa protein 1A OS=Homo sapiens OX=9606 GN=HSPA1A PE=1 SV=1 4.14 1333 - 2.52E+07 - - - -3.4221 - 1.364 0.235 - 281.9 1 2 0 -0.0029 7 0 0 0 5.66E+08 3.96E+09 - - - 1.7594 0.9991 221125_WJC_METTL3_EV_vs_WT_F06.03681.03681.2 9.57E-07 14-Sep R.VGSEC[160.03]PDR.L "tr|A0A7I2V598|A0A7I2V598_HUMAN,tr|H0Y5F5|H0Y5F5_HUMAN,tr|H0Y6X6|H0Y6X6_HUMAN" 3 918.3865 1.34 75266 3681 2 918.382841 460.2005 Polyadenylate-binding protein OS=Homo sapiens OX=9606 GN=PABPC4 PE=1 SV=1 4.37 1333.3 - 1.36E+07 - - - -4.0168 - 1.902 0.598 - 301.3 1 2 0 -0.0037 8 0 0 0 2.42E+08 1.81E+08 - - - 5.3956 0.9132 221125_WJC_METTL3_EV_vs_WT_F06.03683.03683.2 1.15 12-Jul R.K[136.11]LQAQMK[136.11].D "sp|P35580|MYH10_HUMAN,sp|P35749|MYH11_HUMAN,sp|P35579|MYH9_HUMAN" 3 861.5077 0.85 75267 3683 2 861.504777 431.7611 Myosin-10 OS=Homo sapiens OX=9606 GN=MYH10 PE=1 SV=3 10 1333.6 - 4.00E+06 - - - -3.4022 - 1.341 0.048 - 178.6 1 2 0 -0.0029 7 0 0 0 1.24E+08 1.47E+08 - - - 0.3243 0.9989 221125_WJC_METTL3_EV_vs_WT_F06.03685.03685.2 0.0277 18-Nov K.LDDANDAGGK.H "sp|Q02880|TOP2B_HUMAN,tr|E9PCY5|E9PCY5_HUMAN" 2 974.4305 2.13 75268 3685 2 974.427377 488.2225 DNA topoisomerase 2-beta OS=Homo sapiens OX=9606 GN=TOP2B PE=1 SV=3 3.93 1333.8 - 3.80E+06 - - - -3.2091 - 2.177 0.382 - 293.8 1 2 0 -0.0031 10 0 0 0 1.42E+08 6.64E+07 - - - 4.033 0.9883 221125_WJC_METTL3_EV_vs_WT_F06.03699.03699.2 0.389 12-May K.DEVSESR[166.11].R sp|P07196|NFL_HUMAN 1 830.3645 1.84 75277 3699 2 830.362863 416.1895 Neurofilament light polypeptide OS=Homo sapiens OX=9606 GN=NEFL PE=1 SV=3 4.14 1335.4 - 2.40E+06 - - - -2.0268 - 1.212 0.19 - 172.5 1 2 0 -0.0017 7 0 0 0 5.33E+07 2.90E+07 - - - 1.053 0.9857 221125_WJC_METTL3_EV_vs_WT_F06.03707.03707.2 0.0307 12-Jul R.GHVQPIR[166.11].C "sp|Q5JNZ5|RS26L_HUMAN,sp|P62854|RS26_HUMAN" 2 815.4641 0.93 75282 3707 2 815.460653 408.7393 Putative 40S ribosomal protein S26-like 1 OS=Homo sapiens OX=9606 GN=RPS26P11 PE=5 SV=1 9.76 1336.2 - 7.64E+06 - - - -4.2773 - 1.476 0.256 - 271.4 1 2 0 -0.0035 7 0 0 0 6.68E+08 7.22E+08 - - - 2.1644 0.9991 221125_WJC_METTL3_EV_vs_WT_F06.03735.03735.2 0.0102 16-Oct K.TVGSDEAQR.F "sp|Q9NRP4|SDHF3_HUMAN,tr|F8W9V1|F8W9V1_HUMAN" 2 961.4465 1.77 75295 3735 2 961.443997 481.7305 "Succinate dehydrogenase assembly factor 3, mitochondrial OS=Homo sapiens OX=9606 GN=SDHAF3 PE=1 SV=1" 4.37 1339.4 - 5.66E+06 - - - -2.5909 - 1.59 0.453 - 235.2 1 2 0 -0.0025 9 0 0 0 1.76E+08 9.96E+07 - - - 3.7277 0.9985 221125_WJC_METTL3_EV_vs_WT_F06.03743.03743.2 0.00107 16-Nov K.QVAQQEAER[166.11].A "sp|P35232|PHB_HUMAN,tr|C9JZ20|C9JZ20_HUMAN,tr|E7ESE2|E7ESE2_HUMAN,tr|E9PCW0|E9PCW0_HUMAN,tr|C9JW96|C9JW96_HUMAN" 5 1067.5235 1.23 75298 3743 2 1067.519532 534.769 Prohibitin OS=Homo sapiens OX=9606 GN=PHB PE=1 SV=1 4.53 1340.4 - 1.07E+07 - - - -3.7226 - 2.198 0.379 - 657.3 1 2 0 -0.004 9 0 0 0 5.90E+08 4.81E+08 - - - 4.1175 0.9969 221125_WJC_METTL3_EV_vs_WT_F06.03750.03750.2 0.106 14-Aug K.FVEEQHTK.K sp|Q96A49|SYAP1_HUMAN 1 1016.4927 1.4 75299 3750 2 1016.490748 509.2536 Synapse-associated protein 1 OS=Homo sapiens OX=9606 GN=SYAP1 PE=1 SV=1 5.4 1341.4 - 4.02E+06 - - - -1.9302 - 1.329 0.287 - 149.4 1 2 0 -0.002 8 0 0 0 1.08E+08 7.70E+07 - - - 2.018 0.9963 221125_WJC_METTL3_EV_vs_WT_F06.03758.03758.2 0.246 16-Oct K.QVAQQEAER.A "sp|P35232|PHB_HUMAN,tr|C9JZ20|C9JZ20_HUMAN,tr|E7ESE2|E7ESE2_HUMAN,tr|E9PCW0|E9PCW0_HUMAN,tr|C9JW96|C9JW96_HUMAN" 5 1057.5152 1.23 75301 3758 2 1057.511298 529.7649 Prohibitin OS=Homo sapiens OX=9606 GN=PHB PE=1 SV=1 4.53 1342.6 - 2.67E+07 - - - -3.7238 - 1.98 0.274 - 554.8 1 2 0 -0.0039 9 0 0 0 5.90E+08 4.81E+08 - - - 3.0398 0.9953 221125_WJC_METTL3_EV_vs_WT_F06.03765.03765.2 0.00851 12-Sep K.HPELADK.N "sp|Q9NQ39|RS10L_HUMAN,sp|P46783|RS10_HUMAN,tr|A0A2R8Y6L3|A0A2R8Y6L3_HUMAN,tr|F6U211|F6U211_HUMAN,tr|A0A1W2PQS6|A0A1W2PQS6_HUMAN,tr|A0A2R8YFH6|A0A2R8YFH6_HUMAN,tr|A0A2R8Y7H1|A0A2R8Y7H1_HUMAN,tr|S4R435|S4R435_HUMAN" 8 808.4079 1.23 75305 3765 2 808.404427 405.2112 Putative 40S ribosomal protein S10-like OS=Homo sapiens OX=9606 GN=RPS10P5 PE=5 SV=1 5.32 1343.2 - 1.92E+07 - - - -4.3184 - 1.705 0.341 - 220.2 1 2 0 -0.0035 7 0 0 0 2.66E+10 2.17E+10 - - - 3.2492 0.9874 221125_WJC_METTL3_EV_vs_WT_F06.03772.03772.2 0.000527 14-Jul R.ATVNQDTR.L "sp|P14868|SYDC_HUMAN,tr|C9J7S3|C9J7S3_HUMAN,tr|C9JLC1|C9JLC1_HUMAN" 3 903.441 1.2 75308 3772 2 903.435942 452.7278 "Aspartate--tRNA ligase, cytoplasmic OS=Homo sapiens OX=9606 GN=DARS1 PE=1 SV=2" 5.88 1344.1 - 5.31E+06 - - - -5.6086 - 1.648 0.356 - 227.9 1 2 0 -0.0051 8 0 0 0 2.73E+08 2.27E+08 - - - 3.1755 0.9862 221125_WJC_METTL3_EV_vs_WT_F06.03774.03774.2 2.26 14-Sep K.LIEESQRK.M sp|Q9H307|PININ_HUMAN 1 1001.5506 1.87 75309 3774 2 1001.549434 501.7826 Pinin OS=Homo sapiens OX=9606 GN=PNN PE=1 SV=5 6.14 1344.3 - 1.62E+06 - - - -1.1233 - 1.251 0.114 - 240.2 1 2 0 -0.0011 8 0 0 0 2.25E+07 1.20E+07 - - - 0.5581 0.9878 221125_WJC_METTL3_EV_vs_WT_F06.03781.03781.2 0.188 14-Jul R.ATVNQDTR[166.11].L "sp|P14868|SYDC_HUMAN,tr|C9J7S3|C9J7S3_HUMAN,tr|C9JLC1|C9JLC1_HUMAN" 3 913.4493 1.15 75313 3781 2 913.445854 457.7319 "Aspartate--tRNA ligase, cytoplasmic OS=Homo sapiens OX=9606 GN=DARS1 PE=1 SV=2" 5.88 1345.1 - 1.05E+07 - - - -3.7495 - 1.602 0.205 - 273.1 1 2 0 -0.0034 8 0 0 0 2.60E+08 2.26E+08 - - - 1.9753 0.9464 221125_WJC_METTL3_EV_vs_WT_F06.03784.03784.2 1.7 12-Aug R.LNVEEK[136.11]K[136.11].T "sp|Q13283|G3BP1_HUMAN,sp|Q9UN86|G3BP2_HUMAN,tr|A0A7I2YQF2|A0A7I2YQF2_HUMAN,tr|A0A7I2V5M7|A0A7I2V5M7_HUMAN,tr|A0A7I2V647|A0A7I2V647_HUMAN,tr|A0A7I2YQM1|A0A7I2YQM1_HUMAN,tr|A0A7I2YQD9|A0A7I2YQD9_HUMAN,tr|A0A7I2YQR4|A0A7I2YQR4_HUMAN,tr|A0A7I2YQH0|A0A7I2YQH0_HUMAN,tr|A0A7I2V3P9|A0A7I2V3P9_HUMAN" 10 874.5095 2.63 75316 3784 2 874.504895 438.262 Ras GTPase-activating protein-binding protein 1 OS=Homo sapiens OX=9606 GN=G3BP1 PE=1 SV=1 6.14 1345.3 - 3.20E+06 - - - -5.2452 - 1.614 0.145 - 184.2 1 2 0 -0.0046 7 0 0 0 1.26E+08 4.78E+07 - - - 1.6274 0.9677 221125_WJC_METTL3_EV_vs_WT_F06.03793.03793.2 0.115 12-May K.FQGENTK[136.11].S "sp|Q96CT7|CC124_HUMAN,tr|M0R2F5|M0R2F5_HUMAN" 2 830.4014 0.87 75321 3793 2 830.397949 416.208 Coiled-coil domain-containing protein 124 OS=Homo sapiens OX=9606 GN=CCDC124 PE=1 SV=1 6 1346.4 - 2.32E+07 - - - -4.1341 - 1.071 0.293 - 63 1 2 0 -0.0034 7 0 0 0 3.74E+08 4.29E+08 - - - 1.4214 0.989 221125_WJC_METTL3_EV_vs_WT_F06.03795.03795.2 1.33 12-Jul R.QYNEEGR.K "sp|Q9BUJ2|HNRL1_HUMAN,tr|A0A0A0MRA5|A0A0A0MRA5_HUMAN,tr|M0R3F1|M0R3F1_HUMAN,tr|B7Z4B8|B7Z4B8_HUMAN" 4 894.3832 1.18 75322 3795 2 894.381079 448.1989 Heterogeneous nuclear ribonucleoprotein U-like protein 1 OS=Homo sapiens OX=9606 GN=HNRNPUL1 PE=1 SV=2 4.53 1346.6 - 6.52E+06 - - - -2.3256 - 1.31 0.184 - 219.3 1 2 0 -0.0021 7 0 0 0 3.72E+08 3.15E+08 - - - 1.255 0.9984 221125_WJC_METTL3_EV_vs_WT_F06.03796.03796.2 0.00847 18-Oct K.VVTSENEAGK.A "sp|P49321|NASP_HUMAN,tr|E9PPR5|E9PPR5_HUMAN" 2 1032.5088 0.99 75323 3796 2 1032.505297 517.2617 Nuclear autoantigenic sperm protein OS=Homo sapiens OX=9606 GN=NASP PE=1 SV=2 4.53 1346.7 - 1.20E+06 - - - -3.3482 - 1.721 0.418 - 221.4 1 2 0 -0.0035 10 0 0 0 6.19E+07 6.26E+07 - - - 3.6427 0.9983 221125_WJC_METTL3_EV_vs_WT_F06.03798.03798.2 0.00563 14-Aug K.EMPTSGSK.E "sp|P07814|SYEP_HUMAN,tr|V9GYZ6|V9GYZ6_HUMAN" 2 835.3746 0.47 75325 3798 2 835.372059 418.6946 Bifunctional glutamate\proline--tRNA ligase OS=Homo sapiens OX=9606 GN=EPRS1 PE=1 SV=5 6.1 1346.8 - 2.72E+06 - - - -3.0046 - 1.34 0.456 - 292.8 1 2 0 -0.0025 8 0 0 0 6.88E+07 1.46E+08 - - - 3.2909 0.9958 221125_WJC_METTL3_EV_vs_WT_F06.03803.03803.2 0.0982 12-Aug R.C[160.03]QTC[160.03]GYK[136.11].F "sp|P10398|ARAF_HUMAN,sp|P15056|BRAF_HUMAN,sp|P04049|RAF1_HUMAN,tr|H7C560|H7C560_HUMAN,tr|H7C155|H7C155_HUMAN,tr|A0A2U3TZI2|A0A2U3TZI2_HUMAN,tr|A0A2R8Y467|A0A2R8Y467_HUMAN,tr|A0A2R8Y8E0|A0A2R8Y8E0_HUMAN,tr|A0A2R8YDP5|A0A2R8YDP5_HUMAN" 9 923.3721 0.41 75328 3803 2 923.368692 462.6933 Serine\threonine-protein kinase A-Raf OS=Homo sapiens OX=9606 GN=ARAF PE=1 SV=2 8.05 1347.4 - 1.12E+06 - - - -3.6616 - 1.474 0.353 - 310.1 1 2 0 -0.0034 7 0 0 0 5.57E+06 1.35E+07 - - - 2.8765 0.8377 221125_WJC_METTL3_EV_vs_WT_F06.03810.03810.2 2.92 12-Jun R.QYNEEGR[166.11].K "sp|Q9BUJ2|HNRL1_HUMAN,tr|A0A0A0MRA5|A0A0A0MRA5_HUMAN,tr|M0R3F1|M0R3F1_HUMAN,tr|B7Z4B8|B7Z4B8_HUMAN" 4 904.3914 1.78 75332 3810 2 904.388429 453.203 Heterogeneous nuclear ribonucleoprotein U-like protein 1 OS=Homo sapiens OX=9606 GN=HNRNPUL1 PE=1 SV=2 4.53 1348.1 - 1.20E+07 - - - -3.3171 - 1.108 0.063 - 223.4 1 2 0 -0.003 7 0 0 0 3.60E+08 2.03E+08 - - - -0.1697 0.9963 221125_WJC_METTL3_EV_vs_WT_F06.03811.03811.2 0.0057 16-Aug R.DAETDGPEK[136.11].G "sp|Q8TB72|PUM2_HUMAN,tr|A0A0C4DG68|A0A0C4DG68_HUMAN,tr|C9JW01|C9JW01_HUMAN" 3 968.4178 1.32 75333 3811 2 968.414381 485.2162 Pumilio homolog 2 OS=Homo sapiens OX=9606 GN=PUM2 PE=1 SV=2 3.92 1348.3 - 1.61E+06 - - - -3.5512 - 1.298 0.423 - 190.5 1 2 0 -0.0034 9 0 0 0 5.32E+07 4.05E+07 - - - 2.9188 0.9985 221125_WJC_METTL3_EV_vs_WT_F06.03816.03816.2 9.04E-05 18-Nov K.VVTSENEAGK[136.11].A "sp|P49321|NASP_HUMAN,tr|E9PPR5|E9PPR5_HUMAN" 2 1040.523 0.99 75336 3816 2 1040.51861 521.2688 Nuclear autoantigenic sperm protein OS=Homo sapiens OX=9606 GN=NASP PE=1 SV=2 4.53 1348.8 - 3.50E+06 - - - -4.1748 - 1.919 0.501 - 336.5 1 2 0 -0.0043 10 0 0 0 6.19E+07 6.26E+07 - - - 4.5594 0.9575 221125_WJC_METTL3_EV_vs_WT_F06.03817.03817.2 1.5 12-Jul R.R[166.11]DPLANK[136.11].V "sp|Q9BTZ2|DHRS4_HUMAN,tr|F5GWZ1|F5GWZ1_HUMAN" 2 830.4729 1.45 75337 3817 2 830.468135 416.2437 Dehydrogenase\reductase SDR family member 4 OS=Homo sapiens OX=9606 GN=DHRS4 PE=1 SV=3 8.75 1348.9 - 1.43E+07 - - - -5.763 - 1.438 0.261 - 135.6 1 2 0 -0.0048 7 0 0 0 2.28E+09 1.58E+09 - - - 2.1182 0.9943 221125_WJC_METTL3_EV_vs_WT_F06.03820.03820.2 0.66 12-Aug K.SVDALKK.C sp|O94906|PRP6_HUMAN 1 759.4491 2.1 75340 3820 2 759.44923 380.7318 Pre-mRNA-processing factor 6 OS=Homo sapiens OX=9606 GN=PRPF6 PE=1 SV=1 8.31 1349 - 2.49E+06 - - - 0.2317 - 1.256 0.171 - 208.8 1 2 0 0.0002 7 0 0 0 9.46E+07 4.50E+07 - - - 1.0262 0.9998 221125_WJC_METTL3_EV_vs_WT_F06.03821.03821.2 1.83E-05 18-Dec K.TAEEPAASGR.L sp|Q9NQS7|INCE_HUMAN 1 987.4621 1.74 75341 3821 2 987.460697 494.7383 Inner centromere protein OS=Homo sapiens OX=9606 GN=INCENP PE=1 SV=3 4.53 1349.2 - 2.39E+06 - - - -1.4593 - 2.194 0.508 - 592.5 1 2 0 -0.0014 10 0 0 0 8.06E+07 4.63E+07 - - - 4.9858 0.9962 221125_WJC_METTL3_EV_vs_WT_F06.03825.03825.2 0.468 16-Jul R.AVPTGDASK[136.11].C "sp|P21333|FLNA_HUMAN,tr|Q60FE5|Q60FE5_HUMAN" 2 852.4432 1.27 75342 3825 2 852.442318 427.2289 Filamin-A OS=Homo sapiens OX=9606 GN=FLNA PE=1 SV=4 5.88 1349.7 - 1.29E+06 - - - -1.0898 - 1.475 0.175 - 171.6 1 2 0 -0.0009 9 0 0 0 1.19E+08 9.39E+07 - - - 1.4577 0.9922 221125_WJC_METTL3_EV_vs_WT_F06.03833.03833.2 0.00466 12-Jun R.DDGYSTK.D "sp|Q96E39|RMXL1_HUMAN,sp|P38159|RBMX_HUMAN,tr|H3BUY5|H3BUY5_HUMAN,tr|H3BT71|H3BT71_HUMAN,tr|H0Y6E7|H0Y6E7_HUMAN" 5 784.3239 1.5 75347 3833 2 784.321444 393.1692 "RNA binding motif protein, X-linked-like-1 OS=Homo sapiens OX=9606 GN=RBMXL1 PE=1 SV=1" 4.21 1350.5 - 4.89E+07 - - - -3.1479 - 1.318 0.281 - 176.3 1 2 0 -0.0025 7 0 0 0 1.89E+09 1.26E+09 - - - 1.9906 0.9948 221125_WJC_METTL3_EV_vs_WT_F06.03834.03834.2 0.0014 12-Jul R.DDGYSTK[136.11].D "sp|Q96E39|RMXL1_HUMAN,sp|P38159|RBMX_HUMAN,tr|H3BUY5|H3BUY5_HUMAN,tr|H3BT71|H3BT71_HUMAN,tr|H0Y6E7|H0Y6E7_HUMAN" 5 792.3381 1.5 75348 3834 2 792.335022 397.1763 "RNA binding motif protein, X-linked-like-1 OS=Homo sapiens OX=9606 GN=RBMXL1 PE=1 SV=1" 4.21 1350.6 - 3.91E+07 - - - -3.9011 - 1.625 0.307 - 297.7 1 2 0 -0.0031 7 0 0 0 1.89E+09 1.26E+09 - - - 2.8459 0.8184 221125_WJC_METTL3_EV_vs_WT_F06.03835.03835.2 13.4 12-Jun R.ALPEPK[136.11]K[136.11].C sp|Q969V5|MUL1_HUMAN 1 797.4982 1.04 75349 3835 2 797.497345 399.7564 Mitochondrial ubiquitin ligase activator of NFKB 1 OS=Homo sapiens OX=9606 GN=MUL1 PE=1 SV=1 8.64 1350.6 - 3.69E+06 - - - -1.0596 - 0.928 0 - 89.5 1 2 0 -0.0008 7 0 0 0 3.76E+08 3.63E+08 - - - -1.196 0.9916 221125_WJC_METTL3_EV_vs_WT_F06.03840.03840.2 0.0922 12-Aug K.HPELADK[136.11].N "sp|Q9NQ39|RS10L_HUMAN,sp|P46783|RS10_HUMAN,tr|A0A2R8Y6L3|A0A2R8Y6L3_HUMAN,tr|F6U211|F6U211_HUMAN,tr|A0A1W2PQS6|A0A1W2PQS6_HUMAN,tr|A0A2R8YFH6|A0A2R8YFH6_HUMAN,tr|A0A2R8Y7H1|A0A2R8Y7H1_HUMAN,tr|S4R435|S4R435_HUMAN" 8 816.4221 1.27 75351 3840 2 816.418787 409.2183 Putative 40S ribosomal protein S10-like OS=Homo sapiens OX=9606 GN=RPS10P5 PE=5 SV=1 5.32 1351.2 - 4.94E+08 - - - -4.08 - 1.752 0.229 - 178.4 1 2 0 -0.0033 7 0 0 0 2.64E+10 2.08E+10 - - - 2.5081 0.9986 221125_WJC_METTL3_EV_vs_WT_F06.03841.03841.2 0.248 14-Jul R.ADC[160.03]SNIDK.L "sp|Q9Y3A3|PHOCN_HUMAN,tr|S4R3N1|S4R3N1_HUMAN,tr|F8W8B0|F8W8B0_HUMAN" 3 921.3862 1.19 75352 3841 2 921.385504 461.7004 MOB-like protein phocein OS=Homo sapiens OX=9606 GN=MOB4 PE=1 SV=1 4.21 1351.3 - 1.50E+06 - - - -0.751 - 1.524 0.248 - 162.7 1 2 0 -0.0007 8 0 0 0 3.97E+07 3.34E+07 - - - 2.1432 0.9957 221125_WJC_METTL3_EV_vs_WT_F06.03842.03842.2 0.328 16-Aug K.ETDGSSQIK.Q "sp|P78347|GTF2I_HUMAN,tr|A0A494C1K3|A0A494C1K3_HUMAN" 2 963.4509 1.98 75353 3842 2 963.449008 482.7327 General transcription factor II-I OS=Homo sapiens OX=9606 GN=GTF2I PE=1 SV=2 4.37 1351.4 - 2.59E+06 - - - -1.969 - 1.361 0.249 - 134.9 1 2 0 -0.0019 9 0 0 0 5.05E+07 2.55E+07 - - - 1.7712 0.9945 221125_WJC_METTL3_EV_vs_WT_F06.03845.03845.2 0.818 16-Jul K.VAVATPAK[136.11]K[136.11].A "sp|P19338|NUCL_HUMAN,tr|A0A7I2V506|A0A7I2V506_HUMAN,tr|A0A7I2V699|A0A7I2V699_HUMAN,tr|A0A7I2V2U7|A0A7I2V2U7_HUMAN,tr|A0A7I2V3F3|A0A7I2V3F3_HUMAN,tr|A0A7I2V428|A0A7I2V428_HUMAN,tr|A0A7I2V349|A0A7I2V349_HUMAN,tr|H7BY16|H7BY16_HUMAN,tr|A0A7I2V5M5|A0A7I2V5M5_HUMAN,tr|A0A7I2V2S8|A0A7I2V2S8_HUMAN,tr|C9JLB1|C9JLB1_HUMAN" 11 899.5775 1.02 75354 3845 2 899.574211 450.796 Nucleolin OS=Homo sapiens OX=9606 GN=NCL PE=1 SV=3 10 1351.8 - 4.55E+06 - - - -3.6584 - 1.567 0.309 - 155.5 1 2 0 -0.0033 9 0 0 0 2.81E+08 2.75E+08 - - - 2.6217 0.9444 221125_WJC_METTL3_EV_vs_WT_F06.03852.03852.2 0.157 14-Jun R.YDSSNQVK.G "sp|O95983|MBD3_HUMAN,tr|A0A087X1H1|A0A087X1H1_HUMAN,tr|K7EIE8|K7EIE8_HUMAN,tr|A0A087WT34|A0A087WT34_HUMAN,tr|A0A0A0MTS6|A0A0A0MTS6_HUMAN,tr|A0A087WZ12|A0A087WZ12_HUMAN" 6 939.4298 1.52 75359 3852 2 939.425527 470.7222 Methyl-CpG-binding domain protein 3 OS=Homo sapiens OX=9606 GN=MBD3 PE=1 SV=1 5.83 1352.6 - 2.90E+06 - - - -4.5219 - 1.053 0.273 - 75.5 1 2 0 -0.0042 8 0 0 0 1.04E+09 6.80E+08 - - - 1.2118 0.9887 221125_WJC_METTL3_EV_vs_WT_F06.03853.03853.2 0.0633 14-Jul K.K[136.11]VVVSPTK[136.11].K "sp|P19338|NUCL_HUMAN,tr|A0A7I2V506|A0A7I2V506_HUMAN,tr|A0A7I2V699|A0A7I2V699_HUMAN,tr|A0A7I2V2U7|A0A7I2V2U7_HUMAN,tr|A0A7I2V3F3|A0A7I2V3F3_HUMAN,tr|A0A7I2V428|A0A7I2V428_HUMAN,tr|A0A7I2V349|A0A7I2V349_HUMAN,tr|H7BY16|H7BY16_HUMAN,tr|A0A7I2V5M5|A0A7I2V5M5_HUMAN,tr|A0A7I2V2S8|A0A7I2V2S8_HUMAN,tr|C9JLB1|C9JLB1_HUMAN" 11 872.5666 0.81 75360 3853 2 872.562746 437.2906 Nucleolin OS=Homo sapiens OX=9606 GN=NCL PE=1 SV=3 10 1352.6 - 3.97E+06 - - - -4.4203 - 1.698 0.247 - 191.2 1 2 0 -0.0039 8 0 0 0 9.28E+07 1.15E+08 - - - 2.4609 0.9988 221125_WJC_METTL3_EV_vs_WT_F06.03854.03854.2 0.00274 24-Dec K.EAGGGGVGGPGAK.S sp|Q8NC51|PAIRB_HUMAN 1 1012.4938 0.8 75361 3854 2 1012.490302 507.2542 Plasminogen activator inhibitor 1 RNA-binding protein OS=Homo sapiens OX=9606 GN=SERBP1 PE=1 SV=2 6.1 1352.7 - 1.85E+06 - - - -3.4272 - 2.152 0.422 - 428.2 1 2 0 -0.0035 13 0 0 0 3.53E+09 4.41E+09 - - - 4.1238 0.9969 221125_WJC_METTL3_EV_vs_WT_F06.03857.03857.2 0.00807 14-Sep K.VTSHAIVK.E "sp|P07197|NFM_HUMAN,tr|E7ESP9|E7ESP9_HUMAN,tr|E7EMV2|E7EMV2_HUMAN" 3 853.5022 1.8 75362 3857 2 853.499254 427.7584 Neurofilament medium polypeptide OS=Homo sapiens OX=9606 GN=NEFM PE=1 SV=3 8.73 1353.1 - 3.84E+06 - - - -3.3954 - 1.765 0.301 - 218.5 1 2 0 -0.0029 8 0 0 0 1.17E+08 6.52E+07 - - - 2.9768 0.9875 221125_WJC_METTL3_EV_vs_WT_F06.03862.03862.2 0.00489 12-Aug K.AAVHYDR[166.11].S "sp|Q86V81|THOC4_HUMAN,tr|E9PB61|E9PB61_HUMAN" 2 840.4118 1.13 75365 3862 2 840.408074 421.2132 THO complex subunit 4 OS=Homo sapiens OX=9606 GN=ALYREF PE=1 SV=3 6.79 1353.7 - 1.12E+07 - - - -4.399 - 1.399 0.305 - 305.9 1 2 0 -0.0037 7 0 0 0 4.94E+09 4.35E+09 - - - 2.3564 0.9993 221125_WJC_METTL3_EV_vs_WT_F06.03863.03863.2 8.35E-06 24-Dec K.EAGGGGVGGPGAK[136.11].S sp|Q8NC51|PAIRB_HUMAN 1 1020.508 0.8 75366 3863 2 1020.504836 511.2613 Plasminogen activator inhibitor 1 RNA-binding protein OS=Homo sapiens OX=9606 GN=SERBP1 PE=1 SV=2 6.1 1353.7 - 5.95E+06 - - - -3.073 - 2.309 0.446 - 459.7 1 2 0 -0.0031 13 0 0 0 3.53E+09 4.41E+09 - - - 4.4819 0.9848 221125_WJC_METTL3_EV_vs_WT_F06.03884.03884.2 0.000215 12-Oct K.NVHELEK.S "sp|P35580|MYH10_HUMAN,sp|P35749|MYH11_HUMAN,sp|P13533|MYH6_HUMAN" 3 867.445 1.16 75373 3884 2 867.442776 434.7298 Myosin-10 OS=Homo sapiens OX=9606 GN=MYH10 PE=1 SV=3 5.4 1356.5 - 7.29E+06 - - - -2.5996 - 1.79 0.037 - 475.3 1 2 0 -0.0023 7 0 0 0 3.25E+08 2.80E+08 - - - 1.1584 0.995 221125_WJC_METTL3_EV_vs_WT_F06.03908.03908.2 0.00174 14-Jul R.YDSSNQVK[136.11].G "sp|O95983|MBD3_HUMAN,tr|A0A087X1H1|A0A087X1H1_HUMAN,tr|K7EIE8|K7EIE8_HUMAN,tr|A0A087WT34|A0A087WT34_HUMAN,tr|A0A0A0MTS6|A0A0A0MTS6_HUMAN,tr|A0A087WZ12|A0A087WZ12_HUMAN" 6 947.444 1.52 75386 3908 2 947.440895 474.7293 Methyl-CpG-binding domain protein 3 OS=Homo sapiens OX=9606 GN=MBD3 PE=1 SV=1 5.83 1359.2 - 1.37E+07 - - - -3.2509 - 1.36 0.333 - 98.5 1 2 0 -0.0031 8 0 0 0 1.04E+09 6.80E+08 - - - 2.4269 0.9939 221125_WJC_METTL3_EV_vs_WT_F06.03910.03910.2 0.0195 18-Aug K.AMQGAGTQER.V sp|P20073|ANXA7_HUMAN 1 1047.4767 5.69 75387 3910 2 1047.477798 524.7456 Annexin A7 OS=Homo sapiens OX=9606 GN=ANXA7 PE=1 SV=3 6.05 1359.4 - 284664 - - - 1.0081 - 1.559 0.119 - 210.8 1 2 0 0.0011 10 0 0 0 1.24E+07 2.19E+06 - - - 1.1591 0.9995 221125_WJC_METTL3_EV_vs_WT_F06.03915.03915.2 0.00196 16-Sep K.ITGC[160.03]ASPGK.T sp|P50991|TCPD_HUMAN 1 889.4328 0.37 75390 3915 2 889.431119 445.7237 T-complex protein 1 subunit delta OS=Homo sapiens OX=9606 GN=CCT4 PE=1 SV=4 8.22 1359.9 - 2.40E+07 - - - -1.836 - 1.689 0.437 - 177.7 1 2 0 -0.0016 9 0 0 0 8.66E+08 2.32E+09 - - - 3.7845 0.999 221125_WJC_METTL3_EV_vs_WT_F06.03916.03916.2 0.153 16-Nov R.LTEAKPVDK.V "sp|P52815|RM12_HUMAN,tr|B4DLN1|B4DLN1_HUMAN" 2 999.5601 2.13 75391 3916 2 999.557669 500.7873 "39S ribosomal protein L12, mitochondrial OS=Homo sapiens OX=9606 GN=MRPL12 PE=1 SV=2" 6.07 1360 - 2.72E+06 - - - -2.3931 - 2.05 0.306 - 433.2 1 2 0 -0.0024 9 0 0 0 1.50E+09 7.07E+08 - - - 3.3771 0.9609 221125_WJC_METTL3_EV_vs_WT_F06.03917.03917.2 0.000953 12-Aug S.FATASHR.N "sp|Q9NYF8|BCLF1_HUMAN,tr|E9PKI6|E9PKI6_HUMAN,tr|A0A1W2PQ43|A0A1W2PQ43_HUMAN,tr|E9PK91|E9PK91_HUMAN,tr|E9PK09|E9PK09_HUMAN,tr|E9PQN2|E9PQN2_HUMAN" 6 788.3929 2.11 75392 3917 2 788.390872 395.2037 Bcl-2-associated transcription factor 1 OS=Homo sapiens OX=9606 GN=BCLAF1 PE=1 SV=2 9.76 1360.1 - 2.69E+06 - - - -2.618 - 1.783 0.434 - 230.1 1 1 0 -0.0021 7 0 0 0 3.18E+09 1.51E+09 - - - 4.0782 0.9921 221125_WJC_METTL3_EV_vs_WT_F06.03920.03920.2 0.0184 12-Aug R.KYAQAIK.A "sp|P78347|GTF2I_HUMAN,tr|A0A494C1K3|A0A494C1K3_HUMAN" 2 820.4807 1.44 75393 3920 2 820.478707 411.2476 General transcription factor II-I OS=Homo sapiens OX=9606 GN=GTF2I PE=1 SV=2 9.7 1360.4 - 8.13E+07 - - - -2.4157 - 1.698 0.113 - 244.8 1 2 0 -0.002 7 0 0 0 2.29E+09 1.60E+09 - - - 1.5526 0.9995 221125_WJC_METTL3_EV_vs_WT_F06.03922.03922.2 0.000273 14-Aug K.SFATASHR.N "sp|Q9NYF8|BCLF1_HUMAN,tr|E9PKI6|E9PKI6_HUMAN,tr|A0A1W2PQ43|A0A1W2PQ43_HUMAN,tr|E9PK91|E9PK91_HUMAN,tr|E9PK09|E9PK09_HUMAN,tr|E9PQN2|E9PQN2_HUMAN" 6 875.425 1.99 75395 3922 2 875.423135 438.7198 Bcl-2-associated transcription factor 1 OS=Homo sapiens OX=9606 GN=BCLAF1 PE=1 SV=2 9.49 1360.5 - 3.96E+07 - - - -2.0904 - 1.727 0.433 - 238.1 1 2 0 -0.0018 8 0 0 0 2.05E+10 1.03E+10 - - - 3.8864 0.9283 221125_WJC_METTL3_EV_vs_WT_F06.03923.03923.2 0.183 16-Aug K.VLPTHDASK.V "sp|P21333|FLNA_HUMAN,tr|Q60FE5|Q60FE5_HUMAN" 2 966.5134 1.11 75396 3923 2 966.509752 484.264 Filamin-A OS=Homo sapiens OX=9606 GN=FLNA PE=1 SV=4 6.71 1360.6 - 1.66E+06 - - - -3.821 - 1.205 0.147 - 235 1 2 0 -0.0037 9 0 0 0 1.27E+08 1.15E+08 - - - 0.6651 0.8805 221125_WJC_METTL3_EV_vs_WT_F06.03927.03927.2 0.00398 12-Jul S.FATASHR[166.11].N "sp|Q9NYF8|BCLF1_HUMAN,tr|E9PKI6|E9PKI6_HUMAN,tr|A0A1W2PQ43|A0A1W2PQ43_HUMAN,tr|E9PK91|E9PK91_HUMAN,tr|E9PK09|E9PK09_HUMAN,tr|E9PQN2|E9PQN2_HUMAN" 6 798.4012 2.11 75398 3927 2 798.398154 400.2079 Bcl-2-associated transcription factor 1 OS=Homo sapiens OX=9606 GN=BCLAF1 PE=1 SV=2 9.76 1361 - 8.24E+06 - - - -3.8226 - 1.548 0.44 - 166 1 1 0 -0.0031 7 0 0 0 3.18E+09 1.51E+09 - - - 3.6744 0.9989 221125_WJC_METTL3_EV_vs_WT_F06.03928.03928.2 0.00172 14-Jul K.SFATASHR[166.11].N "sp|Q9NYF8|BCLF1_HUMAN,tr|E9PKI6|E9PKI6_HUMAN,tr|A0A1W2PQ43|A0A1W2PQ43_HUMAN,tr|E9PK91|E9PK91_HUMAN,tr|E9PK09|E9PK09_HUMAN,tr|E9PQN2|E9PQN2_HUMAN" 6 885.4332 1.99 75399 3928 2 885.430853 443.7239 Bcl-2-associated transcription factor 1 OS=Homo sapiens OX=9606 GN=BCLAF1 PE=1 SV=2 9.49 1361.1 - 4.91E+07 - - - -2.6902 - 1.611 0.413 - 165.5 1 2 0 -0.0024 8 0 0 0 2.05E+10 1.03E+10 - - - 3.5288 0.9451 221125_WJC_METTL3_EV_vs_WT_F06.03938.03938.2 0.00129 16-Sep C.MDSEAPGSK[136.11].D "sp|Q86U44|MTA70_HUMAN,tr|H0YFV6|H0YFV6_HUMAN" 2 928.4051 0.02 75404 3938 2 928.402562 465.2098 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 4.37 1362.2 - 2.46E+07 - - - -2.7843 - 1.797 0.412 - 261.9 1 1 0 -0.0026 9 0 0 0 3.47E+07 2.25E+09 - - - 3.7789 0.9986 221125_WJC_METTL3_EV_vs_WT_F06.03942.03942.2 0.00413 22-Nov K.QPGAAAAPAGGK.A "sp|Q9P0W2|HM20B_HUMAN,tr|C9J8X5|C9J8X5_HUMAN,tr|C9JQA7|C9JQA7_HUMAN,tr|C9K049|C9K049_HUMAN,tr|B5MDG7|B5MDG7_HUMAN,tr|F8WES5|F8WES5_HUMAN" 6 994.5196 33.77 75406 3942 2 994.516858 498.2671 SWI\SNF-related matrix-associated actin-dependent regulator of chromatin subfamily E member 1-related OS=Homo sapiens OX=9606 GN=HMG20B PE=1 SV=1 8.75 1362.6 - 1.55E+06 - - - -2.7501 - 1.875 0.36 - 388.1 1 2 0 -0.0027 12 0 0 0 1.51E+08 4.46E+06 - - - 3.3531 0.994 221125_WJC_METTL3_EV_vs_WT_F06.03947.03947.2 0.145 14-Aug K.SPNPSTPR.G "sp|O76021|RL1D1_HUMAN,tr|J3QSV6|J3QSV6_HUMAN" 2 854.4246 1.04 75408 3947 2 854.422503 428.2196 Ribosomal L1 domain-containing protein 1 OS=Homo sapiens OX=9606 GN=RSL1D1 PE=1 SV=3 9.47 1363.2 - 2.31E+06 - - - -2.4894 - 1.535 0.2 - 258 1 2 0 -0.0021 8 0 0 0 1.79E+08 1.71E+08 - - - 1.81 0.9987 221125_WJC_METTL3_EV_vs_WT_F06.03949.03949.2 0.0136 16-Jul R.LTEAKPVDK[136.11].V "sp|P52815|RM12_HUMAN,tr|B4DLN1|B4DLN1_HUMAN" 2 1007.5743 - 75409 3949 2 1007.571958 504.7944 "39S ribosomal protein L12, mitochondrial OS=Homo sapiens OX=9606 GN=MRPL12 PE=1 SV=2" 6.07 1363.5 - 524030 - - - -2.2857 - 1.678 0.336 - 145.5 1 2 0 -0.0023 9 0 0 0 - - - - - 3.0194 0.9975 221125_WJC_METTL3_EV_vs_WT_F06.03951.03951.2 0.000594 16-Aug K.VLPTHDASK[136.11].V "sp|P21333|FLNA_HUMAN,tr|Q60FE5|Q60FE5_HUMAN" 2 974.5276 1.11 75410 3951 2 974.525255 488.2711 Filamin-A OS=Homo sapiens OX=9606 GN=FLNA PE=1 SV=4 6.71 1363.7 - 5.09E+06 - - - -2.4525 - 1.375 0.348 - 207.8 1 2 0 -0.0024 9 0 0 0 1.27E+08 1.15E+08 - - - 2.5319 0.9876 221125_WJC_METTL3_EV_vs_WT_F06.03956.03956.2 0.0324 12-Jul R.DLVHSNK.K "sp|Q9Y2W1|TR150_HUMAN,tr|A0A3B3ITZ9|A0A3B3ITZ9_HUMAN" 2 811.4188 2.71 75413 3956 2 811.416219 406.7167 Thyroid hormone receptor-associated protein 3 OS=Homo sapiens OX=9606 GN=THRAP3 PE=1 SV=2 6.74 1364.2 - 3.74E+07 - - - -3.2018 - 1.376 0.216 - 202.3 1 2 0 -0.0026 7 0 0 0 8.54E+09 3.16E+09 - - - 1.6469 0.9909 221125_WJC_METTL3_EV_vs_WT_F06.03957.03957.2 0.00203 18-Sep K.SLDSNGAGEK.S "sp|Q9BXK5|B2L13_HUMAN,tr|A0A087WX97|A0A087WX97_HUMAN,tr|A0A087WTL4|A0A087WTL4_HUMAN" 3 976.4462 1.72 75414 3957 2 976.443586 489.2304 Bcl-2-like protein 13 OS=Homo sapiens OX=9606 GN=BCL2L13 PE=1 SV=1 4.37 1364.3 - 5.14E+06 - - - -2.6299 - 1.432 0.206 - 161.8 1 2 0 -0.0026 10 0 0 0 1.41E+08 8.15E+07 - - - 1.564 0.9982 221125_WJC_METTL3_EV_vs_WT_F06.03958.03958.2 0.0039 14-Aug K.SFATASHR[166.11].N "sp|Q9NYF8|BCLF1_HUMAN,tr|E9PKI6|E9PKI6_HUMAN,tr|A0A1W2PQ43|A0A1W2PQ43_HUMAN,tr|E9PK91|E9PK91_HUMAN,tr|E9PK09|E9PK09_HUMAN,tr|E9PQN2|E9PQN2_HUMAN" 6 885.4332 1.99 75415 3958 2 885.43007 443.7239 Bcl-2-associated transcription factor 1 OS=Homo sapiens OX=9606 GN=BCLAF1 PE=1 SV=2 9.49 1364.3 - 4.09E+08 - - - -3.5745 - 1.743 0.41 - 201.5 1 2 0 -0.0032 8 0 0 0 2.05E+10 1.03E+10 - - - 3.744 0.9806 221125_WJC_METTL3_EV_vs_WT_F06.03960.03960.2 0.00994 14-Jul R.C[160.03]IAC[160.03]QNTK.S sp|P49792|RBP2_HUMAN 1 993.4372 0.81 75417 3960 2 993.432458 497.7259 E3 SUMO-protein ligase RanBP2 OS=Homo sapiens OX=9606 GN=RANBP2 PE=1 SV=2 8.06 1364.4 - 1.42E+06 - - - -4.7592 - 1.66 0.221 - 136.2 1 2 0 -0.0047 8 0 0 0 5.52E+07 6.82E+07 - - - 2.2004 0.9896 221125_WJC_METTL3_EV_vs_WT_F06.03963.03963.2 1.55 14-Jul K.SQGALAGR[166.11].L "sp|Q9H6H4|REEP4_HUMAN,tr|E5RGS2|E5RGS2_HUMAN" 2 768.4118 0.07 75418 3963 2 768.409818 385.2132 Receptor expression-enhancing protein 4 OS=Homo sapiens OX=9606 GN=REEP4 PE=1 SV=1 9.47 1364.8 - 8.46E+06 - - - -2.5416 - 1.577 0.153 - 272.8 2 2 0 -0.002 8 0 0 0 3.51E+07 5.38E+08 - - - 1.4098 0.9891 221125_WJC_METTL3_EV_vs_WT_F06.03964.03964.2 1.55 12-Oct R.K[136.11]LAQQIK[136.11].Q "sp|P13995|MTDC_HUMAN,tr|A0A7I2V2U6|A0A7I2V2U6_HUMAN,tr|B8ZZU9|B8ZZU9_HUMAN,tr|B9A062|B9A062_HUMAN" 4 843.5513 0.96 75419 3964 2 843.548869 422.7829 "Bifunctional methylenetetrahydrofolate dehydrogenase\cyclohydrolase, mitochondrial OS=Homo sapiens OX=9606 GN=MTHFD2 PE=1 SV=2" 10 1364.9 - 5.66E+06 - - - -2.8676 - 1.698 0.113 - 335.1 1 2 0 -0.0024 7 0 0 0 3.02E+08 3.15E+08 - - - 1.5525 0.9991 221125_WJC_METTL3_EV_vs_WT_F06.03965.03965.2 0.00657 14-Sep K.QGVLTHGR.V "sp|P62753|RS6_HUMAN,tr|A2A3R5|A2A3R5_HUMAN" 2 866.4722 0.36 75420 3965 2 866.469866 434.2434 40S ribosomal protein S6 OS=Homo sapiens OX=9606 GN=RPS6 PE=1 SV=1 9.76 1364.9 - 5.35E+06 - - - -2.7502 - 1.973 0.367 - 438.7 1 2 0 -0.0024 8 0 0 0 4.25E+08 1.17E+09 - - - 3.8004 0.971 221125_WJC_METTL3_EV_vs_WT_F06.03967.03967.2 0.123 14-Aug R.EENEGYAK[136.11].L "sp|Q8NI27|THOC2_HUMAN,tr|A0A0C4DG98|A0A0C4DG98_HUMAN" 2 946.4123 0.25 75422 3967 2 946.411124 474.2134 THO complex subunit 2 OS=Homo sapiens OX=9606 GN=THOC2 PE=1 SV=2 4.25 1365.1 - 1.38E+06 - - - -1.2859 - 1.409 0.006 - 258.9 1 2 0 -0.0012 8 0 0 0 8.48E+06 3.42E+07 - - - 0.119 0.9603 221125_WJC_METTL3_EV_vs_WT_F06.03972.03972.2 0.345 12-Jul R.TLTVHEK[136.11].D sp|Q2TAY7|SMU1_HUMAN 1 834.4691 1.05 75424 3972 2 834.465745 418.2418 WD40 repeat-containing protein SMU1 OS=Homo sapiens OX=9606 GN=SMU1 PE=1 SV=2 6.41 1365.7 - 5.20E+06 - - - -3.9822 - 1.429 0.137 - 204.8 1 2 0 -0.0033 7 0 0 0 1.80E+08 1.71E+08 - - - 1.1829 0.985 221125_WJC_METTL3_EV_vs_WT_F06.03974.03974.2 0.00259 14-Aug K.IVGC[160.03]SVHK[136.11].G "sp|P07910|HNRPC_HUMAN,sp|Q86SE5|RALYL_HUMAN,tr|G3V251|G3V251_HUMAN,tr|B4DY08|B4DY08_HUMAN,tr|G3V575|G3V575_HUMAN,tr|B4DSU6|B4DSU6_HUMAN,tr|E5RG71|E5RG71_HUMAN,tr|G3V3K6|G3V3K6_HUMAN,tr|B3KT61|B3KT61_HUMAN,tr|B2R5W2|B2R5W2_HUMAN,tr|G3V4C1|G3V4C1_HUMAN,tr|G3V576|G3V576_HUMAN,tr|G3V5X6|G3V5X6_HUMAN,tr|G3V2H6|G3V2H6_HUMAN,tr|G3V4W0|G3V4W0_HUMAN,tr|G3V555|G3V555_HUMAN,tr|G3V4M8|G3V4M8_HUMAN,tr|G3V2Q1|G3V2Q1_HUMAN" 18 906.4837 1.24 75425 3974 2 906.480917 454.2491 Heterogeneous nuclear ribonucleoproteins C1\C2 OS=Homo sapiens OX=9606 GN=HNRNPC PE=1 SV=4 8.23 1365.9 - 2.10E+07 - - - -3.0392 - 1.432 0.174 - 176 1 2 0 -0.0028 8 0 0 0 1.78E+09 1.43E+09 - - - 1.4082 0.9987 221125_WJC_METTL3_EV_vs_WT_F06.03976.03976.2 0.182 18-Oct K.SLDSNGAGEK[136.11].S "sp|Q9BXK5|B2L13_HUMAN,tr|A0A087WX97|A0A087WX97_HUMAN,tr|A0A087WTL4|A0A087WTL4_HUMAN" 3 984.4604 1.72 75427 3976 2 984.458652 493.2375 Bcl-2-like protein 13 OS=Homo sapiens OX=9606 GN=BCL2L13 PE=1 SV=1 4.37 1366 - 4.02E+06 - - - -1.7289 - 1.498 0.334 - 214.2 1 2 0 -0.0017 10 0 0 0 1.40E+08 8.15E+07 - - - 2.6354 0.9902 221125_WJC_METTL3_EV_vs_WT_F06.03980.03980.2 0.085 12-Jun R.DLVHSNK[136.11].K "sp|Q9Y2W1|TR150_HUMAN,tr|A0A3B3ITZ9|A0A3B3ITZ9_HUMAN" 2 819.433 2.72 75428 3980 2 819.430624 410.7238 Thyroid hormone receptor-associated protein 3 OS=Homo sapiens OX=9606 GN=THRAP3 PE=1 SV=2 6.74 1366.6 - 9.20E+07 - - - -2.9203 - 1.303 0.242 - 116.3 1 2 0 -0.0024 7 0 0 0 8.57E+09 3.15E+09 - - - 1.6663 0.96 221125_WJC_METTL3_EV_vs_WT_F06.03985.03985.2 0.0149 18-Sep R.PAEPEGGTDR.C sp|P78415|IRX3_HUMAN 1 1027.4571 0.94 75431 3985 2 1027.454613 514.7358 Iroquois-class homeodomain protein IRX-3 OS=Homo sapiens OX=9606 GN=IRX3 PE=2 SV=3 4.14 1367.1 - 1.64E+06 - - - -2.3748 - 1.847 0.415 - 324.6 1 1 0 -0.0024 10 0 0 0 4.80E+07 5.12E+07 - - - 3.8181 0.9996 221125_WJC_METTL3_EV_vs_WT_F06.03986.03986.2 0.0082 16-Aug K.LTEAAEQNK.E "sp|P07197|NFM_HUMAN,tr|E7ESP9|E7ESP9_HUMAN,tr|E7EMV2|E7EMV2_HUMAN" 3 1002.4982 3.07 75432 3986 2 1002.496524 502.2564 Neurofilament medium polypeptide OS=Homo sapiens OX=9606 GN=NEFM PE=1 SV=3 4.53 1367.2 - 2.34E+07 - - - -1.6609 - 1.76 0.42 - 221.7 1 2 0 -0.0017 9 0 0 0 7.70E+08 2.51E+08 - - - 3.7781 0.9043 221125_WJC_METTL3_EV_vs_WT_F06.03991.03991.2 0.00996 12-Jul L.VGC[160.03]SVHK[136.11].G "sp|P07910|HNRPC_HUMAN,sp|Q86SE5|RALYL_HUMAN,tr|G3V251|G3V251_HUMAN,tr|B4DY08|B4DY08_HUMAN,tr|G3V575|G3V575_HUMAN,tr|B4DSU6|B4DSU6_HUMAN,tr|E5RG71|E5RG71_HUMAN,tr|G3V3K6|G3V3K6_HUMAN,tr|B3KT61|B3KT61_HUMAN,tr|B2R5W2|B2R5W2_HUMAN,tr|G3V4C1|G3V4C1_HUMAN,tr|G3V576|G3V576_HUMAN,tr|G3V5X6|G3V5X6_HUMAN,tr|G3V2H6|G3V2H6_HUMAN,tr|G3V4W0|G3V4W0_HUMAN,tr|G3V555|G3V555_HUMAN,tr|G3V4M8|G3V4M8_HUMAN,tr|G3V2Q1|G3V2Q1_HUMAN" 18 793.3996 1.26 75434 3991 2 793.397506 397.7071 Heterogeneous nuclear ribonucleoproteins C1\C2 OS=Homo sapiens OX=9606 GN=HNRNPC PE=1 SV=4 8.2 1367.9 - 4.29E+07 - - - -2.6494 - 1.464 0.373 - 142.7 1 1 0 -0.0021 7 0 0 0 1.15E+09 9.14E+08 - - - 3.0031 0.9994 221125_WJC_METTL3_EV_vs_WT_F06.03993.03993.2 0.00712 16-Sep R.LTEAK[136.11]PVDK[136.11].V "sp|P52815|RM12_HUMAN,tr|B4DLN1|B4DLN1_HUMAN" 2 1015.5885 2.13 75436 3993 2 1015.58635 508.8015 "39S ribosomal protein L12, mitochondrial OS=Homo sapiens OX=9606 GN=MRPL12 PE=1 SV=2" 6.07 1368 - 4.70E+06 - - - -2.0786 - 1.992 0.36 - 278.5 1 2 0 -0.0021 9 0 0 0 1.50E+09 7.07E+08 - - - 3.693 0.9988 221125_WJC_METTL3_EV_vs_WT_F06.03994.03994.2 0.00357 12-Sep R.C[160.03]YEC[160.03]GEK.G "sp|Q16629|SRSF7_HUMAN,tr|C9JAB2|C9JAB2_HUMAN,tr|F8WEA1|F8WEA1_HUMAN,tr|A0A0B4J1Z1|A0A0B4J1Z1_HUMAN" 4 944.3368 1.43 75437 3994 2 944.333897 473.1757 Serine\arginine-rich splicing factor 7 OS=Homo sapiens OX=9606 GN=SRSF7 PE=1 SV=1 4.53 1368.1 - 2.94E+06 - - - -3.0773 - 1.51 0.458 - 388.7 1 2 0 -0.0029 7 0 0 0 3.10E+08 2.16E+08 - - - 3.7287 0.9288 221125_WJC_METTL3_EV_vs_WT_F06.03998.03998.2 0.0303 12-Jul L.VGC[160.03]SVHK.G "sp|P07910|HNRPC_HUMAN,sp|Q86SE5|RALYL_HUMAN,tr|G3V251|G3V251_HUMAN,tr|B4DY08|B4DY08_HUMAN,tr|G3V575|G3V575_HUMAN,tr|B4DSU6|B4DSU6_HUMAN,tr|E5RG71|E5RG71_HUMAN,tr|G3V3K6|G3V3K6_HUMAN,tr|B3KT61|B3KT61_HUMAN,tr|B2R5W2|B2R5W2_HUMAN,tr|G3V4C1|G3V4C1_HUMAN,tr|G3V576|G3V576_HUMAN,tr|G3V5X6|G3V5X6_HUMAN,tr|G3V2H6|G3V2H6_HUMAN,tr|G3V4W0|G3V4W0_HUMAN,tr|G3V555|G3V555_HUMAN,tr|G3V4M8|G3V4M8_HUMAN,tr|G3V2Q1|G3V2Q1_HUMAN" 18 785.3854 1.27 75439 3998 2 785.383379 393.7 Heterogeneous nuclear ribonucleoproteins C1\C2 OS=Homo sapiens OX=9606 GN=HNRNPC PE=1 SV=4 8.2 1368.6 - 6.11E+07 - - - -2.5834 - 1.595 0.375 - 132.6 1 1 0 -0.002 7 0 0 0 1.16E+09 9.13E+08 - - - 3.2894 0.9989 221125_WJC_METTL3_EV_vs_WT_F06.04004.04004.2 0.00175 12-Sep R.C[160.03]YEC[160.03]GEK[136.11].G "sp|Q16629|SRSF7_HUMAN,tr|C9JAB2|C9JAB2_HUMAN,tr|F8WEA1|F8WEA1_HUMAN,tr|A0A0B4J1Z1|A0A0B4J1Z1_HUMAN" 4 952.351 1.43 75443 4004 2 952.348113 477.1828 Serine\arginine-rich splicing factor 7 OS=Homo sapiens OX=9606 GN=SRSF7 PE=1 SV=1 4.53 1369.2 - 6.27E+06 - - - -3.0346 - 1.496 0.476 - 441.4 1 2 0 -0.0029 7 0 0 0 3.10E+08 2.16E+08 - - - 3.8321 0.999 221125_WJC_METTL3_EV_vs_WT_F06.04005.04005.2 0.0123 20-Dec K.VEGAGEEQAAK.K sp|P07196|NFL_HUMAN 1 1087.5146 0.93 75444 4005 2 1087.510615 544.7646 Neurofilament light polypeptide OS=Homo sapiens OX=9606 GN=NEFL PE=1 SV=3 4.25 1369.3 - 1.07E+06 - - - -3.6349 - 2.02 0.487 - 504.2 1 2 0 -0.004 11 0 0 0 1.85E+07 1.99E+07 - - - 4.5388 0.9984 221125_WJC_METTL3_EV_vs_WT_F06.04012.04012.2 0.00333 12-Jul R.C[160.03]YETC[160.03]GK.S "sp|Q9BZM1|PG12A_HUMAN,tr|A0A0C4DGC6|A0A0C4DGC6_HUMAN,tr|A0A2R8Y3M9|A0A2R8Y3M9_HUMAN" 3 916.3419 1.6 75447 4012 2 916.338497 459.1782 Group XIIA secretory phospholipase A2 OS=Homo sapiens OX=9606 GN=PLA2G12A PE=1 SV=1 5.99 1370.2 - 1.95E+06 - - - -3.7017 - 1.444 0.518 - 216.4 1 2 0 -0.0034 7 0 0 0 8.21E+07 5.13E+07 - - - 4.0301 0.9954 221125_WJC_METTL3_EV_vs_WT_F06.04017.04017.2 0.0564 14-Jun K.DVSGLHSK.L "sp|P52732|KIF11_HUMAN,tr|A0A7I2YQY4|A0A7I2YQY4_HUMAN,tr|A0A7I2V3A9|A0A7I2V3A9_HUMAN" 3 841.4294 1.95 75448 4017 2 841.427833 421.722 Kinesin-like protein KIF11 OS=Homo sapiens OX=9606 GN=KIF11 PE=1 SV=2 6.74 1370.9 - 1.39E+07 - - - -1.8397 - 1.258 0.26 - 97.3 1 2 0 -0.0015 8 0 0 0 3.98E+08 2.04E+08 - - - 1.6531 0.9998 221125_WJC_METTL3_EV_vs_WT_F06.04019.04019.2 2.48E-05 16-Dec K.HAAADEALK.L sp|O15226|NKRF_HUMAN 1 924.4665 1.32 75450 4019 2 924.464601 463.2405 NF-kappa-B-repressing factor OS=Homo sapiens OX=9606 GN=NKRF PE=1 SV=2 5.32 1371 - 5.97E+06 - - - -2.0487 - 2.435 0.507 - 478.1 1 2 0 -0.0019 9 0 0 0 1.39E+08 1.05E+08 - - - 5.3598 0.9998 221125_WJC_METTL3_EV_vs_WT_F06.04020.04020.2 0.000221 16-Nov K.HAAADEALK[136.11].L sp|O15226|NKRF_HUMAN 1 932.4807 1.37 75451 4020 2 932.481323 467.2476 NF-kappa-B-repressing factor OS=Homo sapiens OX=9606 GN=NKRF PE=1 SV=2 5.32 1371.1 - 5.19E+06 - - - 0.6735 - 2.055 0.473 - 331 1 2 0 0.0006 9 0 0 0 1.44E+08 1.05E+08 - - - 4.6182 0.9996 221125_WJC_METTL3_EV_vs_WT_F06.04026.04026.2 0.00153 14-Aug R.ITPTQQQR[166.11].Q "sp|Q9H0E2|TOLIP_HUMAN,tr|E9PNS3|E9PNS3_HUMAN,tr|F2Z2Y8|F2Z2Y8_HUMAN" 3 980.5279 1.06 75455 4026 2 980.526678 491.2712 Toll-interacting protein OS=Homo sapiens OX=9606 GN=TOLLIP PE=1 SV=1 9.75 1371.8 - 2.59E+06 - - - -1.2085 - 1.542 0.439 - 296.1 1 2 0 -0.0012 8 0 0 0 4.39E+07 4.16E+07 - - - 3.5892 0.9985 221125_WJC_METTL3_EV_vs_WT_F06.04030.04030.2 0.232 16-Jul R.AHPAMEAER.- "sp|Q8TB05|UBAD1_HUMAN,tr|D3DUE0|D3DUE0_HUMAN,tr|K7EM88|K7EM88_HUMAN,tr|K7EQ49|K7EQ49_HUMAN" 4 1010.4604 2.01 75457 4030 2 1010.459483 506.2375 UBA-like domain-containing protein 1 OS=Homo sapiens OX=9606 GN=UBALD1 PE=1 SV=1 5.4 1372.3 - 3.17E+06 - - - -0.8719 - 1.571 0.244 - 173.7 1 2 0 -0.0009 9 0 0 0 5.31E+07 2.64E+07 - - - 2.1497 0.9985 221125_WJC_METTL3_EV_vs_WT_F06.04034.04034.2 0.115 14-Aug K.VTTHPLAK.D "sp|Q99497|PARK7_HUMAN,tr|K7EN27|K7EN27_HUMAN,tr|K7ELW0|K7ELW0_HUMAN" 3 865.5022 2.03 75459 4034 2 865.500957 433.7584 Parkinson disease protein 7 OS=Homo sapiens OX=9606 GN=PARK7 PE=1 SV=2 8.73 1372.8 - 4.93E+06 - - - -1.3807 - 1.549 0.268 - 242.8 1 2 0 -0.0012 8 0 0 0 3.36E+08 1.65E+08 - - - 2.3399 0.9951 221125_WJC_METTL3_EV_vs_WT_F06.04039.04039.2 0.397 16-Aug K.ELDQQSTTK[136.11].A sp|O00311|CDC7_HUMAN 1 1056.5179 0.41 75464 4039 2 1056.51607 529.2662 Cell division cycle 7-related protein kinase OS=Homo sapiens OX=9606 GN=CDC7 PE=1 SV=1 4.37 1373 - 1.05E+06 - - - -1.7018 - 1.531 0.171 - 214.7 1 2 0 -0.0018 9 0 0 0 8.60E+06 2.10E+07 - - - 1.5357 0.9567 221125_WJC_METTL3_EV_vs_WT_F06.04044.04044.2 0.00367 12-Jun V.TTHPLAK.D "sp|Q99497|PARK7_HUMAN,tr|K7EN27|K7EN27_HUMAN,tr|K7ELW0|K7ELW0_HUMAN" 3 766.4337 2.05 75467 4044 2 766.432809 384.2241 Parkinson disease protein 7 OS=Homo sapiens OX=9606 GN=PARK7 PE=1 SV=2 8.44 1373.7 - 1.21E+07 - - - -1.2121 - 1.388 0.381 - 180.8 1 1 0 -0.0009 7 0 0 0 3.93E+08 1.92E+08 - - - 2.8936 0.9982 221125_WJC_METTL3_EV_vs_WT_F06.04050.04050.2 0.00965 14-Aug K.ELEDPHAK.K "sp|O60231|DHX16_HUMAN,tr|Q5SQH5|Q5SQH5_HUMAN,tr|A0A140T8Y5|A0A140T8Y5_HUMAN" 3 937.4505 4.58 75473 4050 2 937.449639 469.7325 Pre-mRNA-splicing factor ATP-dependent RNA helicase DHX16 OS=Homo sapiens OX=9606 GN=DHX16 PE=1 SV=2 4.65 1374 - 1.68E+06 - - - -0.9302 - 1.319 0.288 - 256.4 1 2 0 -0.0009 8 0 0 0 8.71E+07 1.90E+07 - - - 2.0029 0.9785 221125_WJC_METTL3_EV_vs_WT_F06.04051.04051.2 0.000738 16-Jul R.GPYESGSGH.S "sp|Q86YZ3|HORN_HUMAN,sp|Q86YZ3|HORN_HUMAN,sp|Q86YZ3|HORN_HUMAN,sp|Q86YZ3|HORN_HUMAN" 4 889.3566 - 75474 4051 2 889.355256 445.6856 Hornerin OS=Homo sapiens OX=9606 GN=HRNR PE=1 SV=2 5.24 1374 - 2.61E+06 - - - -1.5224 - 1.387 0.528 - 166.2 1 1 0 -0.0014 9 0 0 0 - - - - - 3.8868 0.9884 221125_WJC_METTL3_EV_vs_WT_F06.04052.04052.2 0.574 14-Aug R.QLQEEQEK[136.11].K sp|Q9NQS7|INCE_HUMAN 1 1038.5073 1.55 75475 4052 2 1038.506781 520.2609 Inner centromere protein OS=Homo sapiens OX=9606 GN=INCENP PE=1 SV=3 4.25 1374.2 - 488973 - - - -0.5036 - 1.258 0.109 - 299.1 1 2 0 -0.0005 8 0 0 0 4.16E+07 2.68E+07 - - - 0.5381 0.999 221125_WJC_METTL3_EV_vs_WT_F06.04056.04056.2 0.0172 14-Sep K.VTTHPLAK[136.11].D "sp|Q99497|PARK7_HUMAN,tr|K7EN27|K7EN27_HUMAN,tr|K7ELW0|K7ELW0_HUMAN" 3 873.5164 2.76 75477 4056 2 873.514852 437.7655 Parkinson disease protein 7 OS=Homo sapiens OX=9606 GN=PARK7 PE=1 SV=2 8.73 1374.7 - 8.26E+06 - - - -1.7172 - 1.578 0.334 - 276.7 1 2 0 -0.0015 8 0 0 0 4.38E+08 1.59E+08 - - - 2.8832 0.9994 221125_WJC_METTL3_EV_vs_WT_F06.04057.04057.2 0.000953 16-Aug R.APSTSDSVR[166.11].L "sp|P23193|TCEA1_HUMAN,tr|A0A1W2PRL9|A0A1W2PRL9_HUMAN,tr|A0A1W2PPZ5|A0A1W2PPZ5_HUMAN" 3 928.4489 1.06 75478 4057 2 928.447406 465.2317 Transcription elongation factor A protein 1 OS=Homo sapiens OX=9606 GN=TCEA1 PE=1 SV=2 5.88 1374.7 - 6.19E+06 - - - -1.6565 - 1.677 0.386 - 214.4 1 2 0 -0.0015 9 0 0 0 4.86E+08 4.58E+08 - - - 3.3872 0.9996 221125_WJC_METTL3_EV_vs_WT_F06.04058.04058.2 9.43E-06 16-Aug R.APSTSDSVR.L "sp|P23193|TCEA1_HUMAN,tr|A0A1W2PRL9|A0A1W2PRL9_HUMAN,tr|A0A1W2PPZ5|A0A1W2PPZ5_HUMAN" 3 918.4407 1.06 75479 4058 2 918.439495 460.2276 Transcription elongation factor A protein 1 OS=Homo sapiens OX=9606 GN=TCEA1 PE=1 SV=2 5.88 1374.8 - 6.97E+06 - - - -1.2837 - 1.778 0.38 - 218.9 1 2 0 -0.0012 9 0 0 0 4.86E+08 4.58E+08 - - - 3.5122 0.837 221125_WJC_METTL3_EV_vs_WT_F06.04059.04059.2 0.496 14-Jul F.ASQEIAEK[136.11].A "sp|P55795|HNRH2_HUMAN,sp|P52597|HNRPF_HUMAN,sp|P31943|HNRH1_HUMAN,tr|E5RGH4|E5RGH4_HUMAN,tr|H0YB39|H0YB39_HUMAN,tr|E5RGV0|E5RGV0_HUMAN,tr|E9PCY7|E9PCY7_HUMAN,tr|D6RIU0|D6RIU0_HUMAN,tr|D6RBM0|D6RBM0_HUMAN,tr|G8JLB6|G8JLB6_HUMAN,tr|E7EN40|E7EN40_HUMAN" 11 882.4538 1.48 75480 4059 2 882.452094 442.2342 Heterogeneous nuclear ribonucleoprotein H2 OS=Homo sapiens OX=9606 GN=HNRNPH2 PE=1 SV=1 4.53 1374.8 - 3.78E+06 - - - -1.9468 - 1.487 0.238 - 201.1 1 1 0 -0.0017 8 0 0 0 9.31E+07 6.29E+07 - - - 1.9949 0.9853 221125_WJC_METTL3_EV_vs_WT_F06.04063.04063.2 0.0188 12-Jul R.VPVVNKR.N sp|Q9P2D1|CHD7_HUMAN 1 810.5076 0.59 75482 4063 2 810.506136 406.2611 Chromodomain-helicase-DNA-binding protein 7 OS=Homo sapiens OX=9606 GN=CHD7 PE=1 SV=3 11 1375.2 - 3.61E+06 - - - -1.7717 - 1.357 0.103 - 226.1 1 2 0 -0.0014 7 0 0 0 1.01E+08 1.70E+08 - - - 0.7686 0.9993 221125_WJC_METTL3_EV_vs_WT_F06.04064.04064.2 0.0441 16-Aug R.EADVDQDGR.V sp|Q9NZT1|CALL5_HUMAN 1 1003.4207 76.34 75483 4064 2 1003.419495 502.7176 Calmodulin-like protein 5 OS=Homo sapiens OX=9606 GN=CALML5 PE=1 SV=2 3.84 1375.3 - 1.23E+06 - - - -1.168 - 1.698 0.327 - 264.3 1 2 0 -0.0012 9 0 0 0 9.53E+07 1.25E+06 - - - 2.9876 0.9982 221125_WJC_METTL3_EV_vs_WT_F06.04071.04071.2 0.307 12-Jul R.NDEELNK.L "sp|P16104|H2AX_HUMAN,sp|Q9BTM1|H2AJ_HUMAN,sp|Q93077|H2A1C_HUMAN,sp|Q99878|H2A1J_HUMAN,sp|Q16777|H2A2C_HUMAN,sp|Q8IUE6|H2A2B_HUMAN,sp|Q96QV6|H2A1A_HUMAN,sp|P04908|H2A1B_HUMAN,sp|P20671|H2A1D_HUMAN,sp|P0C0S8|H2A1_HUMAN,sp|Q6FI13|H2A2A_HUMAN,sp|Q96KK5|H2A1H_HUMAN,sp|Q7L7L0|H2A3_HUMAN,tr|A0A0U1RR32|A0A0U1RR32_HUMAN,tr|A0A0U1RRH7|A0A0U1RRH7_HUMAN,tr|A0A3B3IS11|A0A3B3IS11_HUMAN,tr|H0YFX9|H0YFX9_HUMAN" 17 860.3876 1.41 75487 4071 2 860.386708 431.2011 Histone H2AX OS=Homo sapiens OX=9606 GN=H2AX PE=1 SV=2 4.14 1376.1 - 1.80E+06 - - - -1.0088 - 1.454 0.245 - 239.6 1 2 0 -0.0009 7 0 0 0 1.51E+10 1.07E+10 - - - 2.0363 0.9975 221125_WJC_METTL3_EV_vs_WT_F06.04078.04078.2 0.253 14-Jun K.SSQPLASK[136.11].Q "sp|P17096|HMGA1_HUMAN,tr|A0A669KAX1|A0A669KAX1_HUMAN,tr|A0A1W2PRV2|A0A1W2PRV2_HUMAN" 3 824.4483 0.69 75490 4078 2 824.447204 413.2314 High mobility group protein HMG-I\HMG-Y OS=Homo sapiens OX=9606 GN=HMGA1 PE=1 SV=3 8.47 1377.2 - 3.67E+07 - - - -1.3682 - 1.28 0.288 - 152.8 1 2 0 -0.0011 8 0 0 0 7.41E+08 1.08E+09 - - - 1.9123 0.9984 221125_WJC_METTL3_EV_vs_WT_F06.04079.04079.2 0.016 14-Jun K.EAPGPNPR[166.11].V "sp|Q6P9B6|MEAK7_HUMAN,tr|H3BM75|H3BM75_HUMAN" 2 846.4223 0.1 75491 4079 2 846.422328 424.2184 MTOR-associated protein MEAK7 OS=Homo sapiens OX=9606 GN=MEAK7 PE=1 SV=2 6.1 1377.2 - 826438 - - - -0.0095 - 1.143 0.34 - 103.6 1 2 0 0 8 0 0 0 2.82E+06 2.89E+07 - - - 1.9553 0.7707 221125_WJC_METTL3_EV_vs_WT_F06.04081.04081.2 24.4 16-May R.KELENLDSR[166.11].L "sp|O43196|MSH5_HUMAN,tr|A2ABF0|A2ABF0_HUMAN,tr|A0A140T9I9|A0A140T9I9_HUMAN,tr|A0A0G2JK42|A0A0G2JK42_HUMAN,tr|A0A0G2JJ70|A0A0G2JJ70_HUMAN,tr|A2ABE9|A2ABE9_HUMAN,tr|A0A0G2JIC1|A0A0G2JIC1_HUMAN,tr|A0A140T927|A0A140T927_HUMAN,tr|A0A140T9P6|A0A140T9P6_HUMAN,tr|A0A140T940|A0A140T940_HUMAN,tr|A0A0G2JK88|A0A0G2JK88_HUMAN,tr|A0A140T9J3|A0A140T9J3_HUMAN,tr|H7C2J4|H7C2J4_HUMAN,tr|A0A0G2JHB4|A0A0G2JHB4_HUMAN,tr|A0A140T982|A0A140T982_HUMAN,tr|A0A024RCV8|A0A024RCV8_HUMAN" 16 1112.5701 - 75493 4081 2 1112.567925 557.2923 MutS protein homolog 5 OS=Homo sapiens OX=9606 GN=MSH5 PE=1 SV=1 4.68 1377.4 - 188498 - - - -1.9747 - 1 0.018 - 54.9 3 2 0 -0.0022 9 0 0 0 - - - - - -1.0399 0.9978 221125_WJC_METTL3_EV_vs_WT_F06.04084.04084.2 0.249 12-Jun R.NDEELNK[136.11].L "sp|P16104|H2AX_HUMAN,sp|Q9BTM1|H2AJ_HUMAN,sp|Q93077|H2A1C_HUMAN,sp|Q99878|H2A1J_HUMAN,sp|Q16777|H2A2C_HUMAN,sp|Q8IUE6|H2A2B_HUMAN,sp|Q96QV6|H2A1A_HUMAN,sp|P04908|H2A1B_HUMAN,sp|P20671|H2A1D_HUMAN,sp|P0C0S8|H2A1_HUMAN,sp|Q6FI13|H2A2A_HUMAN,sp|Q96KK5|H2A1H_HUMAN,sp|Q7L7L0|H2A3_HUMAN,tr|A0A0U1RR32|A0A0U1RR32_HUMAN,tr|A0A0U1RRH7|A0A0U1RRH7_HUMAN,tr|A0A3B3IS11|A0A3B3IS11_HUMAN,tr|H0YFX9|H0YFX9_HUMAN" 17 868.4018 1.41 75494 4084 2 868.400513 435.2082 Histone H2AX OS=Homo sapiens OX=9606 GN=H2AX PE=1 SV=2 4.14 1377.8 - 2.68E+07 - - - -1.4544 - 1.385 0.27 - 230.1 1 2 0 -0.0013 7 0 0 0 1.51E+10 1.07E+10 - - - 2.0668 0.9955 221125_WJC_METTL3_EV_vs_WT_F06.04086.04086.2 0.181 18-Jun R.GAAASPEPAR[166.11].A sp|P84157|MXRA7_HUMAN 1 935.47 2.62 75496 4086 2 935.469287 468.7423 Matrix-remodeling-associated protein 7 OS=Homo sapiens OX=9606 GN=MXRA7 PE=1 SV=1 6 1377.9 - 1.20E+06 - - - -0.7771 - 1.46 0.199 - 131.1 5 2 0 -0.0007 10 0 0 0 1.15E+08 4.39E+07 - - - 1.2547 0.9997 221125_WJC_METTL3_EV_vs_WT_F06.04093.04093.2 0.00162 18-Sep R.IEESGNDEAR.V "sp|Q8TAQ2|SMRC2_HUMAN,tr|F8VXC8|F8VXC8_HUMAN" 2 1118.484 14.61 75500 4093 2 1118.483279 560.2493 SWI\SNF complex subunit SMARCC2 OS=Homo sapiens OX=9606 GN=SMARCC2 PE=1 SV=1 4 1378.7 - 1.08E+06 - - - -0.641 - 1.76 0.43 - 260.6 1 2 0 -0.0007 10 0 0 0 2.12E+07 1.45E+06 - - - 3.7947 0.9886 221125_WJC_METTL3_EV_vs_WT_F06.04099.04099.2 6.59E-05 18-Oct G.AQTAAATAPR.L "sp|P21912|SDHB_HUMAN,tr|A0A087WWT1|A0A087WWT1_HUMAN" 2 956.5039 0.61 75504 4099 2 956.502426 479.2592 "Succinate dehydrogenase [ubiquinone] iron-sulfur subunit, mitochondrial OS=Homo sapiens OX=9606 GN=SDHB PE=1 SV=3" 9.79 1379.3 - 1.37E+07 - - - -1.586 - 2.093 0.517 - 605.3 1 1 0 -0.0015 10 0 0 0 3.03E+08 4.93E+08 - - - 4.9207 0.9996 221125_WJC_METTL3_EV_vs_WT_F06.04102.04102.2 0.000841 14-Jul R.GNDSSVPR.N "sp|Q8WVM8|SCFD1_HUMAN,tr|A0A7I2V4U2|A0A7I2V4U2_HUMAN,tr|A0A7I2V5Z4|A0A7I2V5Z4_HUMAN,tr|B7Z5N7|B7Z5N7_HUMAN,tr|A0A7I2V5I2|A0A7I2V5I2_HUMAN,tr|A0A7I2V2U5|A0A7I2V2U5_HUMAN,tr|A0A7I2V448|A0A7I2V448_HUMAN,tr|A0A7I2V320|A0A7I2V320_HUMAN,tr|A0A7I2V3G4|A0A7I2V3G4_HUMAN,tr|A0A7I2V3B4|A0A7I2V3B4_HUMAN,tr|G3V2M8|G3V2M8_HUMAN,tr|A0A7I2V4R0|A0A7I2V4R0_HUMAN" 12 830.3882 1.41 75507 4102 2 830.386981 416.2014 Sec1 family domain-containing protein 1 OS=Homo sapiens OX=9606 GN=SCFD1 PE=1 SV=4 5.84 1379.4 - 2.97E+06 - - - -1.5222 - 1.726 0.423 - 233.6 1 2 0 -0.0013 8 0 0 0 1.13E+08 7.97E+07 - - - 3.811 0.9921 221125_WJC_METTL3_EV_vs_WT_F06.04108.04108.2 0.576 16-Aug R.ASPAPAPSR.S "sp|P78411|IRX5_HUMAN,tr|H0YML8|H0YML8_HUMAN" 2 852.4454 2.34 75511 4108 2 852.444554 427.23 Iroquois-class homeodomain protein IRX-5 OS=Homo sapiens OX=9606 GN=IRX5 PE=1 SV=3 9.79 1380 - 2.47E+06 - - - -0.9526 - 1.473 0.117 - 176.1 2 2 0 -0.0008 9 0 0 0 4.70E+07 2.01E+07 - - - 0.8909 0.9953 221125_WJC_METTL3_EV_vs_WT_F06.04116.04116.2 0.677 14-Jun R.EGVTAMHK[136.11].L "sp|Q5T2N8|ATD3C_HUMAN,sp|Q5T9A4|ATD3B_HUMAN,sp|Q9NVI7|ATD3A_HUMAN,tr|Q5SV16|Q5SV16_HUMAN,tr|A0A5K1VW56|A0A5K1VW56_HUMAN" 5 879.4364 0.1 75516 4116 2 879.437267 440.7255 ATPase family AAA domain-containing protein 3C OS=Homo sapiens OX=9606 GN=ATAD3C PE=2 SV=2 6.85 1380.9 - 2.72E+06 - - - 1.0006 - 1.117 0.267 - 153.6 1 2 0 0.0009 8 0 0 0 5.60E+06 5.48E+07 - - - 1.3465 0.9965 221125_WJC_METTL3_EV_vs_WT_F06.04120.04120.2 0.0452 12-Jun K.EQVGHIR[166.11].A sp|Q15208|STK38_HUMAN 1 847.454 3.64 75518 4120 2 847.453703 424.7343 Serine\threonine-protein kinase 38 OS=Homo sapiens OX=9606 GN=STK38 PE=1 SV=1 6.85 1381.3 - 4.08E+06 - - - -0.3151 - 1.241 0.221 - 185.7 1 2 0 -0.0003 7 0 0 0 1.80E+09 4.95E+08 - - - 1.3574 0.9477 221125_WJC_METTL3_EV_vs_WT_F06.04125.04125.2 1.56 14-Jul K.SSQPLASK.Q "sp|P17096|HMGA1_HUMAN,tr|A0A669KAX1|A0A669KAX1_HUMAN,tr|A0A1W2PRV2|A0A1W2PRV2_HUMAN" 3 816.4341 0.68 75520 4125 2 816.431833 409.2243 High mobility group protein HMG-I\HMG-Y OS=Homo sapiens OX=9606 GN=HMGA1 PE=1 SV=3 8.47 1381.9 - 4.68E+06 - - - -2.8159 - 1.039 0.168 - 175.3 1 2 0 -0.0023 8 0 0 0 7.65E+08 1.12E+09 - - - 0.3965 0.9672 221125_WJC_METTL3_EV_vs_WT_F06.04133.04133.2 0.638 12-Sep R.SKEITVR.G "sp|P17844|DDX5_HUMAN,tr|J3QR02|J3QR02_HUMAN,tr|A0A7I2V507|A0A7I2V507_HUMAN,tr|J3KTA4|J3KTA4_HUMAN,tr|J3KTQ4|J3KTQ4_HUMAN,tr|A0A7I2V2S0|A0A7I2V2S0_HUMAN,tr|J3QRQ7|J3QRQ7_HUMAN" 7 831.4814 1.47 75526 4133 2 831.479809 416.748 Probable ATP-dependent RNA helicase DDX5 OS=Homo sapiens OX=9606 GN=DDX5 PE=1 SV=1 8.46 1382.8 - 8.76E+06 - - - -1.9339 - 1.841 0.145 - 343.6 1 2 1 -0.0016 7 0 0 0 1.97E+08 1.34E+08 - - - 2.0453 0.9988 221125_WJC_METTL3_EV_vs_WT_F06.04137.04137.2 0.0121 18-Sep R.LGGNPGTNSR.V "sp|Q969G3|SMCE1_HUMAN,tr|A0A2R8Y855|A0A2R8Y855_HUMAN,tr|A0A2R8YEB8|A0A2R8YEB8_HUMAN,tr|J3QL66|J3QL66_HUMAN,tr|B4DGM3|B4DGM3_HUMAN,tr|J3QKS7|J3QKS7_HUMAN,tr|J3QR61|J3QR61_HUMAN,tr|J3QKX6|J3QKX6_HUMAN,tr|A0A2R8YDQ4|A0A2R8YDQ4_HUMAN" 9 971.4785 1.76 75528 4137 2 971.477158 486.7465 SWI\SNF-related matrix-associated actin-dependent regulator of chromatin subfamily E member 1 OS=Homo sapiens OX=9606 GN=SMARCE1 PE=1 SV=2 9.75 1383.2 - 3.52E+06 - - - -1.3371 - 1.598 0.296 - 271.9 1 2 0 -0.0013 10 0 0 0 4.16E+08 2.36E+08 - - - 2.5353 0.9986 221125_WJC_METTL3_EV_vs_WT_F06.04144.04144.2 0.00206 14-Sep R.SQK[136.11]PVMVK[136.11].R sp|P46779|RL28_HUMAN 1 931.5496 0.77 75533 4144 2 931.54698 466.7821 60S ribosomal protein L28 OS=Homo sapiens OX=9606 GN=RPL28 PE=1 SV=3 10 1383.8 - 4.64E+06 - - - -2.7835 - 1.867 0.328 - 280.8 1 2 0 -0.0026 8 0 0 0 8.21E+07 1.06E+08 - - - 3.3458 0.8769 221125_WJC_METTL3_EV_vs_WT_F06.04149.04149.2 4.96 12-Jun R.QHVTTLR.E "sp|O43663|PRC1_HUMAN,tr|H0YM42|H0YM42_HUMAN" 2 853.477 0.08 75535 4149 2 853.477496 427.7458 Protein regulator of cytokinesis 1 OS=Homo sapiens OX=9606 GN=PRC1 PE=1 SV=2 9.76 1384.4 - 1.96E+06 - - - 0.5812 - 0.999 0.017 - 153.5 2 2 0 0.0005 7 0 0 0 2.04E+07 2.46E+08 - - - -0.9712 0.9993 221125_WJC_METTL3_EV_vs_WT_F06.04150.04150.2 0.00041 18-Nov R.LGGNPGTNSR[166.11].V "sp|Q969G3|SMCE1_HUMAN,tr|A0A2R8Y855|A0A2R8Y855_HUMAN,tr|A0A2R8YEB8|A0A2R8YEB8_HUMAN,tr|J3QL66|J3QL66_HUMAN,tr|B4DGM3|B4DGM3_HUMAN,tr|J3QKS7|J3QKS7_HUMAN,tr|J3QR61|J3QR61_HUMAN,tr|J3QKX6|J3QKX6_HUMAN,tr|A0A2R8YDQ4|A0A2R8YDQ4_HUMAN" 9 981.4867 1.92 75536 4150 2 981.483826 491.7506 SWI\SNF-related matrix-associated actin-dependent regulator of chromatin subfamily E member 1 OS=Homo sapiens OX=9606 GN=SMARCE1 PE=1 SV=2 9.75 1384.4 - 5.96E+06 - - - -2.9557 - 2.012 0.473 - 316.6 1 2 0 -0.0029 10 0 0 0 4.08E+08 2.13E+08 - - - 4.4851 0.9982 221125_WJC_METTL3_EV_vs_WT_F06.04153.04153.2 6.37E-05 14-Sep R.FNDGSDEK.K "sp|P25705|ATPA_HUMAN,tr|K7EK77|K7EK77_HUMAN,tr|K7ENJ4|K7ENJ4_HUMAN" 3 910.3668 1.69 75537 4153 2 910.364745 456.1907 "ATP synthase subunit alpha, mitochondrial OS=Homo sapiens OX=9606 GN=ATP5F1A PE=1 SV=1" 4.03 1384.8 - 2.72E+07 - - - -2.3024 - 1.687 0.288 - 168.7 1 2 0 -0.0021 8 0 0 0 5.21E+08 3.08E+08 - - - 2.7447 0.9994 221125_WJC_METTL3_EV_vs_WT_F06.04154.04154.2 0.00541 14-Aug R.FNDGSDEK[136.11].K "sp|P25705|ATPA_HUMAN,tr|K7EK77|K7EK77_HUMAN,tr|K7ENJ4|K7ENJ4_HUMAN" 3 918.381 1.69 75538 4154 2 918.379182 460.1978 "ATP synthase subunit alpha, mitochondrial OS=Homo sapiens OX=9606 GN=ATP5F1A PE=1 SV=1" 4.03 1384.9 - 1.71E+07 - - - -2.0242 - 1.518 0.471 - 129.1 1 2 0 -0.0019 8 0 0 0 5.21E+08 3.08E+08 - - - 3.7781 0.9988 221125_WJC_METTL3_EV_vs_WT_F06.04155.04155.2 0.00518 14-Jul K.NMTPGQNR[166.11].E sp|P49790|NU153_HUMAN 1 926.4268 1.5 75539 4155 2 926.425981 464.2207 Nuclear pore complex protein Nup153 OS=Homo sapiens OX=9606 GN=NUP153 PE=1 SV=2 9.75 1384.9 - 3.92E+06 - - - -0.8506 - 1.407 0.3 - 227.7 1 2 0 -0.0008 8 0 0 0 1.31E+08 8.72E+07 - - - 2.2864 0.9857 221125_WJC_METTL3_EV_vs_WT_F06.04159.04159.2 1.3 12-Jun R.DQINAEK[136.11].K sp|Q14966|ZN638_HUMAN 1 824.4119 0.83 75541 4159 2 824.411852 413.2132 Zinc finger protein 638 OS=Homo sapiens OX=9606 GN=ZNF638 PE=1 SV=2 4.37 1385.4 - 2.36E+06 - - - -0.1152 - 1.212 0.098 - 144.4 1 2 0 -0.0001 7 0 0 0 8.92E+07 1.07E+08 - - - 0.374 0.9973 221125_WJC_METTL3_EV_vs_WT_F06.04160.04160.2 0.0105 14-Jul R.VVYTDHQR.L "sp|Q99626|CDX2_HUMAN,sp|O14627|CDX4_HUMAN,sp|P47902|CDX1_HUMAN,tr|A0A087WTJ6|A0A087WTJ6_HUMAN" 4 1016.5039 1.49 75542 4160 2 1016.501536 509.2592 Homeobox protein CDX-2 OS=Homo sapiens OX=9606 GN=CDX2 PE=1 SV=3 6.71 1385.5 - 887144 - - - -2.3679 - 1.306 0.345 - 231.4 1 2 0 -0.0024 8 0 0 0 1.48E+07 9.95E+06 - - - 2.3936 0.9997 221125_WJC_METTL3_EV_vs_WT_F06.04166.04166.2 0.0245 13/22 R.GPAGPAAQQAAK.L "sp|O15417|TNC18_HUMAN,tr|H9KVB4|H9KVB4_HUMAN" 2 1065.5567 3.59 75546 4166 2 1065.554678 533.7856 Trinucleotide repeat-containing gene 18 protein OS=Homo sapiens OX=9606 GN=TNRC18 PE=1 SV=3 8.75 1386.2 - 608689 - - - -1.9042 - 2.523 0.449 - 590.5 1 2 0 -0.002 12 0 0 0 7.75E+07 2.16E+07 - - - 4.7917 0.9991 221125_WJC_METTL3_EV_vs_WT_F06.04173.04173.2 0.512 14-Jul R.YASENVNK.L "sp|Q9H0U4|RAB1B_HUMAN,sp|P62820|RAB1A_HUMAN,tr|E9PLD0|E9PLD0_HUMAN,tr|E7END7|E7END7_HUMAN" 4 923.4349 1.27 75551 4173 2 923.433642 462.7247 Ras-related protein Rab-1B OS=Homo sapiens OX=9606 GN=RAB1B PE=1 SV=1 6 1386.9 - 9.07E+06 - - - -1.3201 - 1.589 0.312 - 118.7 1 2 0 -0.0012 8 0 0 0 1.09E+09 8.54E+08 - - - 2.7418 0.9987 221125_WJC_METTL3_EV_vs_WT_F06.04175.04175.2 0.202 22-Sep R.GPAGPAAQQAAK[136.11].L "sp|O15417|TNC18_HUMAN,tr|H9KVB4|H9KVB4_HUMAN" 2 1073.5709 3.64 75553 4175 2 1073.568202 537.7927 Trinucleotide repeat-containing gene 18 protein OS=Homo sapiens OX=9606 GN=TNRC18 PE=1 SV=3 8.75 1387.1 - 563030 - - - -2.5196 - 2.013 0.317 - 189.9 1 2 0 -0.0027 12 0 0 0 7.72E+07 2.12E+07 - - - 3.2223 0.9995 221125_WJC_METTL3_EV_vs_WT_F06.04176.04176.2 0.000435 22-Oct K.IGSTSGAEAANK.L sp|Q9NR09|BIRC6_HUMAN 1 1104.5411 0.22 75554 4176 2 1104.538104 553.2778 Baculoviral IAP repeat-containing protein 6 OS=Homo sapiens OX=9606 GN=BIRC6 PE=1 SV=2 6 1387.2 - 328381 - - - -2.7278 - 2.276 0.457 - 212.4 1 2 0 -0.003 12 0 0 0 2.73E+06 1.24E+07 - - - 4.5794 0.9984 221125_WJC_METTL3_EV_vs_WT_F06.04180.04180.2 0.0461 14-Jun K.NMTPGQNR.E sp|P49790|NU153_HUMAN 1 916.4185 1.16 75556 4180 2 916.417075 459.2165 Nuclear pore complex protein Nup153 OS=Homo sapiens OX=9606 GN=NUP153 PE=1 SV=2 9.75 1387.6 - 5.96E+06 - - - -1.5539 - 1.268 0.356 - 139.7 1 2 0 -0.0014 8 0 0 0 1.41E+08 1.21E+08 - - - 2.3861 0.9982 221125_WJC_METTL3_EV_vs_WT_F06.04182.04182.2 0.285 16-Sep K.EIAENQEAK.L "sp|Q13625|ASPP2_HUMAN,tr|H7C5L8|H7C5L8_HUMAN" 2 1030.4931 7.23 75558 4182 2 1030.493718 516.2538 Apoptosis-stimulating of p53 protein 2 OS=Homo sapiens OX=9606 GN=TP53BP2 PE=1 SV=2 4.25 1387.8 - 1.01E+06 - - - 0.5958 - 1.562 0.224 - 294.9 1 2 0 0.0006 9 0 0 0 1.73E+07 2.39E+06 - - - 1.9855 0.9616 221125_WJC_METTL3_EV_vs_WT_F06.04185.04185.2 0.0531 16-Sep K.VGGR[166.11]LEDTK[136.11].L "sp|P48643|TCPE_HUMAN,tr|E9PCA1|E9PCA1_HUMAN,tr|B7ZAR1|B7ZAR1_HUMAN,tr|E7ENZ3|E7ENZ3_HUMAN" 4 991.5417 0.06 75559 4185 2 991.53884 496.7781 T-complex protein 1 subunit epsilon OS=Homo sapiens OX=9606 GN=CCT5 PE=1 SV=1 6.04 1388.2 - 2.49E+06 - - - -2.9136 - 1.878 0.224 - 352.6 1 2 1 -0.0029 9 0 0 0 3.92E+06 6.41E+07 - - - 2.5178 0.995 221125_WJC_METTL3_EV_vs_WT_F06.04190.04190.2 0.254 14-Aug K.SGNFGGSR.N "sp|P22626|ROA2_HUMAN,tr|A0A024RA28|A0A024RA28_HUMAN,tr|A0A7I2V4N1|A0A7I2V4N1_HUMAN,tr|A0A7I2V4I6|A0A7I2V4I6_HUMAN,tr|A0A7I2V323|A0A7I2V323_HUMAN,tr|A0A7I2V3P1|A0A7I2V3P1_HUMAN,tr|A0A7I2V3P7|A0A7I2V3P7_HUMAN" 7 780.3515 1.29 75563 4190 2 780.350129 391.183 Heterogeneous nuclear ribonucleoproteins A2\B1 OS=Homo sapiens OX=9606 GN=HNRNPA2B1 PE=1 SV=2 9.47 1388.6 - 4.17E+06 - - - -1.712 - 1.25 0.246 - 230.5 1 2 0 -0.0013 8 0 0 0 6.02E+09 4.67E+09 - - - 1.5305 0.9995 221125_WJC_METTL3_EV_vs_WT_F06.04195.04195.2 0.00519 14-Jul R.ENTQTTIK[136.11].L "sp|P61978|HNRPK_HUMAN,tr|Q5T6W2|Q5T6W2_HUMAN" 2 941.4909 1.2 75567 4195 2 941.489605 471.7527 Heterogeneous nuclear ribonucleoprotein K OS=Homo sapiens OX=9606 GN=HNRNPK PE=1 SV=1 6.1 1389 - 1.34E+07 - - - -1.402 - 1.501 0.434 - 253.1 1 2 0 -0.0013 8 0 0 0 3.36E+09 2.80E+09 - - - 3.471 0.9972 221125_WJC_METTL3_EV_vs_WT_F06.04196.04196.2 0.0193 12-May K.QESTEYR.R "sp|P08670|VIME_HUMAN,tr|B0YJC5|B0YJC5_HUMAN,tr|B0YJC4|B0YJC4_HUMAN" 3 911.3985 1.94 75568 4196 2 911.397189 456.7065 Vimentin OS=Homo sapiens OX=9606 GN=VIM PE=1 SV=4 4.53 1389.1 - 7.05E+06 - - - -1.411 - 1.092 0.34 - 97.5 1 2 0 -0.0013 7 0 0 0 5.18E+09 2.67E+09 - - - 1.8307 0.9971 221125_WJC_METTL3_EV_vs_WT_F06.04197.04197.2 0.0404 12-Jul K.ILEEDHK[136.11].G "sp|Q9NRA8|4ET_HUMAN,tr|B1AKL4|B1AKL4_HUMAN" 2 890.4589 0.43 75569 4197 2 890.45665 446.2367 Eukaryotic translation initiation factor 4E transporter OS=Homo sapiens OX=9606 GN=EIF4ENIF1 PE=1 SV=2 4.65 1389.1 - 3.54E+06 - - - -2.5234 - 1.298 0.349 - 125.2 1 2 0 -0.0022 7 0 0 0 7.81E+07 1.81E+08 - - - 2.4444 0.9978 221125_WJC_METTL3_EV_vs_WT_F06.04207.04207.2 0.00128 16-Sep R.EQEEAAAPR[166.11].G sp|Q8IYI6|EXOC8_HUMAN 1 1009.4704 1.61 75576 4207 2 1009.469901 505.7425 Exocyst complex component 8 OS=Homo sapiens OX=9606 GN=EXOC8 PE=1 SV=2 4.25 1390.1 - 2.23E+06 - - - -0.5022 - 1.714 0.153 - 439.9 1 2 0 -0.0005 9 0 0 0 2.68E+08 1.66E+08 - - - 1.7298 0.998 221125_WJC_METTL3_EV_vs_WT_F06.04210.04210.2 1.63 14-Aug K.SGNFGGSR[166.11].N "sp|P22626|ROA2_HUMAN,tr|A0A024RA28|A0A024RA28_HUMAN,tr|A0A7I2V4N1|A0A7I2V4N1_HUMAN,tr|A0A7I2V4I6|A0A7I2V4I6_HUMAN,tr|A0A7I2V323|A0A7I2V323_HUMAN,tr|A0A7I2V3P1|A0A7I2V3P1_HUMAN,tr|A0A7I2V3P7|A0A7I2V3P7_HUMAN" 7 790.3597 1.29 75577 4210 2 790.357819 396.1871 Heterogeneous nuclear ribonucleoproteins A2\B1 OS=Homo sapiens OX=9606 GN=HNRNPA2B1 PE=1 SV=2 9.47 1390.5 - 5.54E+07 - - - -2.4242 - 1.675 0.285 - 365.4 1 2 0 -0.0019 8 0 0 0 6.02E+09 4.67E+09 - - - 2.7011 0.9634 221125_WJC_METTL3_EV_vs_WT_F06.04211.04211.2 1.89 12-Jul R.EVAELKK.A "sp|Q8NCX0|CC150_HUMAN,sp|P35580|MYH10_HUMAN,sp|Q9Y6D9|MD1L1_HUMAN,tr|B8ZZI4|B8ZZI4_HUMAN,tr|C9JKI7|C9JKI7_HUMAN" 5 815.4753 1.61 75578 4211 2 815.472788 408.7449 Coiled-coil domain-containing protein 150 OS=Homo sapiens OX=9606 GN=CCDC150 PE=1 SV=2 6.24 1390.6 - 4.56E+06 - - - -3.0424 - 1.318 0.114 - 231.1 1 2 0 -0.0025 7 0 0 0 1.29E+08 8.02E+07 - - - 0.7571 0.9998 221125_WJC_METTL3_EV_vs_WT_F06.04213.04213.2 9.73E-07 13/22 K.LATEGSSGATEK.M sp|Q9NW68|BSDC1_HUMAN 1 1149.5513 1.4 75580 4213 2 1149.549159 575.7829 BSD domain-containing protein 1 OS=Homo sapiens OX=9606 GN=BSDC1 PE=1 SV=1 4.53 1390.8 - 2.08E+06 - - - -1.9034 - 2.559 0.527 - 654.5 1 2 0 -0.0022 12 0 0 0 1.84E+08 1.32E+08 - - - 5.405 0.999 221125_WJC_METTL3_EV_vs_WT_F06.04217.04217.2 0.00439 14-Jul R.ENTQTTIK.L "sp|P61978|HNRPK_HUMAN,tr|Q5T6W2|Q5T6W2_HUMAN" 2 933.4767 1.2 75582 4217 2 933.47537 467.7456 Heterogeneous nuclear ribonucleoprotein K OS=Homo sapiens OX=9606 GN=HNRNPK PE=1 SV=1 6.1 1391.3 - 1.06E+08 - - - -1.4516 - 1.274 0.409 - 182.7 1 2 0 -0.0014 8 0 0 0 3.36E+09 2.80E+09 - - - 2.7918 0.9867 221125_WJC_METTL3_EV_vs_WT_F06.04218.04218.2 0.0199 16-Sep R.EQEEAAAPR.G sp|Q8IYI6|EXOC8_HUMAN 1 999.4621 1.61 75583 4218 2 999.458163 500.7383 Exocyst complex component 8 OS=Homo sapiens OX=9606 GN=EXOC8 PE=1 SV=2 4.25 1391.3 - 6.55E+06 - - - -3.9771 - 1.776 0.182 - 484.5 1 2 0 -0.004 9 0 0 0 2.67E+08 1.66E+08 - - - 2.0457 0.9826 221125_WJC_METTL3_EV_vs_WT_F06.04219.04219.2 0.0705 14-Aug R.ISK[136.11]EEAMR[166.11].W "sp|P62913|RL11_HUMAN,tr|Q5VVC8|Q5VVC8_HUMAN" 2 980.508 0.96 75584 4219 2 980.505488 491.2613 60S ribosomal protein L11 OS=Homo sapiens OX=9606 GN=RPL11 PE=1 SV=2 6.14 1391.4 - 1.36E+07 - - - -2.5477 - 1.576 0.356 - 310.3 1 2 1 -0.0025 8 0 0 0 3.91E+08 4.07E+08 - - - 3.0416 0.9962 221125_WJC_METTL3_EV_vs_WT_F06.04220.04220.2 0.0132 14-Aug R.ISKEEAMR.W "sp|P62913|RL11_HUMAN,tr|Q5VVC8|Q5VVC8_HUMAN" 2 962.4855 0.96 75585 4220 2 962.48547 482.25 60S ribosomal protein L11 OS=Homo sapiens OX=9606 GN=RPL11 PE=1 SV=2 6.14 1391.4 - 8.64E+06 - - - -0.0478 - 1.706 0.375 - 292.8 1 2 1 0 8 0 0 0 3.91E+08 4.06E+08 - - - 3.4217 0.9993 221125_WJC_METTL3_EV_vs_WT_F06.04223.04223.2 0.006 14-Jul K.DSENTPVK.G sp|Q92922|SMRC1_HUMAN 1 888.4189 2.39 75587 4223 2 888.417538 445.2167 SWI\SNF complex subunit SMARCC1 OS=Homo sapiens OX=9606 GN=SMARCC1 PE=1 SV=3 4.37 1391.7 - 1.23E+07 - - - -1.506 - 1.359 0.424 - 154.2 1 2 0 -0.0013 8 0 0 0 3.34E+08 1.40E+08 - - - 3.0974 0.9996 221125_WJC_METTL3_EV_vs_WT_F06.04232.04232.2 0.000776 22-Dec K.LATEGSSGATEK[136.11].M sp|Q9NW68|BSDC1_HUMAN 1 1157.5655 1.4 75593 4232 2 1157.562809 579.79 BSD domain-containing protein 1 OS=Homo sapiens OX=9606 GN=BSDC1 PE=1 SV=1 4.53 1392.5 - 6.75E+06 - - - -2.3653 - 2.364 0.425 - 328.5 1 2 0 -0.0027 12 0 0 0 1.84E+08 1.32E+08 - - - 4.4429 0.9809 221125_WJC_METTL3_EV_vs_WT_F06.04233.04233.2 0.00116 16-Sep R.VGEEEEC[160.03]SR[166.11].Q "sp|Q7Z406|MYH14_HUMAN,tr|M0QY43|M0QY43_HUMAN" 2 1103.4429 1.38 75594 4233 2 1103.434978 552.7287 Myosin-14 OS=Homo sapiens OX=9606 GN=MYH14 PE=1 SV=2 4.09 1392.7 - 934266 - - - -7.1549 - 1.998 0.385 - 247.3 1 2 0 -0.0079 9 0 0 0 3.19E+07 2.32E+07 - - - 3.8845 0.998 221125_WJC_METTL3_EV_vs_WT_F06.04236.04236.2 0.0156 12-Jul R.QQLQTTR[166.11].Q "sp|Q9UMS4|PRP19_HUMAN,tr|F5GY56|F5GY56_HUMAN,tr|F5H2I0|F5H2I0_HUMAN" 3 883.4751 1.04 75595 4236 2 883.472901 442.7448 Pre-mRNA-processing factor 19 OS=Homo sapiens OX=9606 GN=PRPF19 PE=1 SV=1 9.75 1393.1 - 3.43E+07 - - - -2.4879 - 1.557 0.312 - 300.7 1 2 0 -0.0022 7 0 0 0 2.13E+09 2.05E+09 - - - 2.7477 0.9972 221125_WJC_METTL3_EV_vs_WT_F06.04243.04243.2 0.132 13/18 K.IAAQQSETAR[166.11].L "sp|Q5VT06|CE350_HUMAN,tr|H0YD38|H0YD38_HUMAN,tr|H0Y6Q4|H0Y6Q4_HUMAN" 3 1083.5548 2.35 75598 4243 2 1083.551997 542.7847 Centrosome-associated protein 350 OS=Homo sapiens OX=9606 GN=CEP350 PE=1 SV=1 6 1393.9 - 954411 - - - -2.5924 - 1.901 0.229 - 736.4 1 2 0 -0.0028 10 0 0 0 2.07E+08 8.79E+07 - - - 2.5246 0.9988 221125_WJC_METTL3_EV_vs_WT_F06.04244.04244.2 0.198 14-Aug R.EEDEPEER.S "sp|Q1KMD3|HNRL2_HUMAN,tr|H3BQZ7|H3BQZ7_HUMAN" 2 1031.4043 2.96 75599 4244 2 1031.402084 516.7095 Heterogeneous nuclear ribonucleoprotein U-like protein 2 OS=Homo sapiens OX=9606 GN=HNRNPUL2 PE=1 SV=1 3.83 1394.1 - 1.68E+06 - - - -2.1951 - 1.472 0.39 - 229.8 1 2 0 -0.0023 8 0 0 0 4.70E+07 1.59E+07 - - - 3.0869 0.9956 221125_WJC_METTL3_EV_vs_WT_F06.04247.04247.2 0.0315 12-Jul R.QQLQTTR.Q "sp|Q9UMS4|PRP19_HUMAN,tr|F5GY56|F5GY56_HUMAN,tr|F5H2I0|F5H2I0_HUMAN" 3 873.4668 1.06 75600 4247 2 873.464995 437.7407 Pre-mRNA-processing factor 19 OS=Homo sapiens OX=9606 GN=PRPF19 PE=1 SV=1 9.75 1394.4 - 8.64E+07 - - - -2.0997 - 1.494 0.205 - 337.3 1 2 0 -0.0018 7 0 0 0 2.13E+09 2.01E+09 - - - 1.8266 0.9796 221125_WJC_METTL3_EV_vs_WT_F06.04248.04248.2 0.000469 18-Dec K.IAAQQSETAR.L "sp|Q5VT06|CE350_HUMAN,tr|H0YD38|H0YD38_HUMAN,tr|H0Y6Q4|H0Y6Q4_HUMAN" 3 1073.5465 2.37 75601 4248 2 1073.537194 537.7805 Centrosome-associated protein 350 OS=Homo sapiens OX=9606 GN=CEP350 PE=1 SV=1 6 1394.6 - 2.55E+06 - - - -8.702 - 2.314 0.451 - 613.7 1 2 0 -0.0093 10 0 0 0 2.09E+08 8.79E+07 - - - 4.711 0.9999 221125_WJC_METTL3_EV_vs_WT_F06.04252.04252.2 0.000348 16-Dec R.VGEEEEC[160.03]SR.Q "sp|Q7Z406|MYH14_HUMAN,tr|M0QY43|M0QY43_HUMAN" 2 1093.4346 1.39 75603 4252 2 1093.432964 547.7246 Myosin-14 OS=Homo sapiens OX=9606 GN=MYH14 PE=1 SV=2 4.09 1395.1 - 904416 - - - -1.4989 - 2.288 0.553 - 942.6 1 2 0 -0.0016 9 0 0 0 3.21E+07 2.32E+07 - - - 5.5195 0.998 221125_WJC_METTL3_EV_vs_WT_F06.04255.04255.2 0.0253 14-Jun K.ETISTANK.A sp|Q9HBM1|SPC25_HUMAN 1 862.4396 5.29 75605 4255 2 862.438649 432.2271 Kinetochore protein Spc25 OS=Homo sapiens OX=9606 GN=SPC25 PE=1 SV=1 6.1 1395.3 - 8.70E+06 - - - -1.1166 - 1.348 0.274 - 98.5 1 2 0 -0.001 8 0 0 0 7.73E+08 1.46E+08 - - - 1.9651 0.9976 221125_WJC_METTL3_EV_vs_WT_F06.04261.04261.2 0.0613 14-Nov R.IYHEQQVK[136.11].T "sp|Q5UIP0|RIF1_HUMAN,tr|H7C2B5|H7C2B5_HUMAN" 2 1051.5542 1 75609 4261 2 1051.55211 526.7844 Telomere-associated protein RIF1 OS=Homo sapiens OX=9606 GN=RIF1 PE=1 SV=2 6.75 1396 - 1.68E+06 - - - -1.9818 - 1.625 0.238 - 513.6 1 2 0 -0.0021 8 0 0 0 2.72E+07 2.74E+07 - - - 2.2625 0.9986 221125_WJC_METTL3_EV_vs_WT_F06.04266.04266.2 0.105 18-Oct R.RAPPPAVAAR.E sp|Q6SPF0|SAMD1_HUMAN 1 1004.5879 2.04 75612 4266 2 1004.585615 503.3013 Sterile alpha motif domain-containing protein 1 OS=Homo sapiens OX=9606 GN=SAMD1 PE=1 SV=1 12 1396.7 - 1.68E+06 - - - -2.3223 - 1.976 0.281 - 170 1 2 0 -0.0023 10 0 0 0 2.33E+08 1.14E+08 - - - 3.0168 0.995 221125_WJC_METTL3_EV_vs_WT_F06.04272.04272.2 0.441 14-Jul K.KLAEPAER.Y "sp|Q92615|LAR4B_HUMAN,tr|A0A087X183|A0A087X183_HUMAN,tr|H0Y4V9|H0Y4V9_HUMAN" 3 912.5029 1.3 75616 4272 2 912.501303 457.2587 La-related protein 4B OS=Homo sapiens OX=9606 GN=LARP4B PE=1 SV=3 6.14 1397.2 - 6.19E+07 - - - -1.7293 - 1.63 0.138 - 234.7 1 2 0 -0.0016 8 0 0 0 1.12E+09 8.60E+08 - - - 1.5333 0.9988 221125_WJC_METTL3_EV_vs_WT_F06.04276.04276.2 0.118 14-Sep K.SQVISNAK.N "sp|P34932|HSP74_HUMAN,tr|A0A087WTS8|A0A087WTS8_HUMAN,tr|A0A087WYC1|A0A087WYC1_HUMAN" 3 845.4607 0.09 75618 4276 2 845.459096 423.7376 Heat shock 70 kDa protein 4 OS=Homo sapiens OX=9606 GN=HSPA4 PE=1 SV=4 8.47 1397.7 - 6.57E+06 - - - -1.8747 - 1.793 0.276 - 436.8 1 2 0 -0.0016 8 0 0 0 1.30E+08 1.45E+09 - - - 2.84 0.9149 221125_WJC_METTL3_EV_vs_WT_F06.04278.04278.2 0.0852 16-Aug K.VTSMSTQTK[136.11].V "sp|Q9UQN3|CHM2B_HUMAN,tr|A0A087WW88|A0A087WW88_HUMAN" 2 989.4943 3.49 75620 4278 2 989.488155 495.7544 Charged multivesicular body protein 2b OS=Homo sapiens OX=9606 GN=CHMP2B PE=1 SV=1 8.72 1397.9 - 1.53E+06 - - - -6.2062 - 1.437 0.227 - 178.1 1 2 0 -0.0061 9 0 0 0 2.71E+07 7.79E+06 - - - 1.7646 0.9966 221125_WJC_METTL3_EV_vs_WT_F06.04286.04286.2 0.105 14-Sep R.IYHEQQVK.T "sp|Q5UIP0|RIF1_HUMAN,tr|H7C2B5|H7C2B5_HUMAN" 2 1043.54 1 75625 4286 2 1043.538916 522.7773 Telomere-associated protein RIF1 OS=Homo sapiens OX=9606 GN=RIF1 PE=1 SV=2 6.75 1398.8 - 1.34E+06 - - - -1.033 - 1.27 0.238 - 161.2 1 2 0 -0.0011 8 0 0 0 2.72E+07 2.74E+07 - - - 1.5194 0.9996 221125_WJC_METTL3_EV_vs_WT_F06.04287.04287.2 0.000197 14-Aug R.YANNSNYK.N "sp|Q96A72|MGN2_HUMAN,sp|P61326|MGN_HUMAN,tr|F5H6N1|F5H6N1_HUMAN" 3 972.4301 1.69 75626 4287 2 972.428294 487.2223 Protein mago nashi homolog 2 OS=Homo sapiens OX=9606 GN=MAGOHB PE=1 SV=1 8.5 1398.9 - 7.47E+06 - - - -1.8675 - 1.434 0.519 - 146.7 1 2 0 -0.0018 8 0 0 0 6.81E+08 4.03E+08 - - - 3.9609 0.9977 221125_WJC_METTL3_EV_vs_WT_F06.04288.04288.2 0.11 18-Oct R.R[166.11]APPPAVAAR[166.11].E sp|Q6SPF0|SAMD1_HUMAN 1 1024.6045 2.1 75627 4288 2 1024.603268 513.3095 Sterile alpha motif domain-containing protein 1 OS=Homo sapiens OX=9606 GN=SAMD1 PE=1 SV=1 12 1399 - 1.66E+06 - - - -1.1907 - 1.687 0.19 - 212.9 1 2 0 -0.0012 10 0 0 0 2.45E+08 1.17E+08 - - - 1.9037 0.9988 221125_WJC_METTL3_EV_vs_WT_F06.04294.04294.2 0.00312 14-Jul K.VMDVHDGK.V sp|P02533|K1C14_HUMAN 1 899.4171 40.39 75631 4294 2 899.415796 450.7158 "Keratin, type I cytoskeletal 14 OS=Homo sapiens OX=9606 GN=KRT14 PE=1 SV=4" 5.21 1399.6 - 6.94E+06 - - - -1.4521 - 1.322 0.362 - 133.6 1 2 0 -0.0013 8 0 0 0 6.17E+08 1.53E+07 - - - 2.5562 0.9904 221125_WJC_METTL3_EV_vs_WT_F06.04295.04295.2 0.177 14-Jul R.LVEDEER[166.11]R[166.11].W "sp|Q14204|DYHC1_HUMAN,tr|A0A7P0T8N2|A0A7P0T8N2_HUMAN,tr|A0A7P0T9C4|A0A7P0T9C4_HUMAN,tr|A0A7P0TBJ7|A0A7P0TBJ7_HUMAN,tr|A0A804HHY6|A0A804HHY6_HUMAN,tr|A0A7P0T9K2|A0A7P0T9K2_HUMAN,tr|A0A7P0TB64|A0A7P0TB64_HUMAN,tr|A0A2R8Y706|A0A2R8Y706_HUMAN,tr|A0A7P0T916|A0A7P0T916_HUMAN,tr|A0A7P0TB75|A0A7P0TB75_HUMAN,tr|A0A7P0T8W5|A0A7P0T8W5_HUMAN,tr|A0A7P0TAF3|A0A7P0TAF3_HUMAN,tr|A0A7P0T9F1|A0A7P0T9F1_HUMAN,tr|A0A7P0TAW9|A0A7P0TAW9_HUMAN,tr|A0A7P0TA13|A0A7P0TA13_HUMAN,tr|A0A7P0TAV5|A0A7P0TAV5_HUMAN,tr|A0A7P0T7V5|A0A7P0T7V5_HUMAN,tr|A0A7P0T9R4|A0A7P0T9R4_HUMAN,tr|A0A2R8Y5T0|A0A2R8Y5T0_HUMAN,tr|A0A7P0T990|A0A7P0T990_HUMAN,tr|A0A2R8YFZ7|A0A2R8YFZ7_HUMAN,tr|A0A7P0T825|A0A7P0T825_HUMAN,tr|A0A2R8Y6H2|A0A2R8Y6H2_HUMAN,tr|A0A7P0TAM4|A0A7P0TAM4_HUMAN" 24 1064.5365 0.47 75632 4295 2 1064.533604 533.2755 Cytoplasmic dynein 1 heavy chain 1 OS=Homo sapiens OX=9606 GN=DYNC1H1 PE=1 SV=5 4.41 1399.7 - 816896 - - - -2.7458 - 1.353 0.221 - 97.4 1 2 0 -0.0029 8 0 0 0 1.13E+07 2.42E+07 - - - 1.5842 0.8909 221125_WJC_METTL3_EV_vs_WT_F06.04301.04301.2 1.73 12-Jun K.SQTEVPK.R sp|P46013|KI67_HUMAN 1 787.4076 1.29 75635 4301 2 787.406909 394.7111 Proliferation marker protein Ki-67 OS=Homo sapiens OX=9606 GN=MKI67 PE=1 SV=2 5.72 1400.5 - 2.92E+06 - - - -0.856 - 1.023 0.001 - 184.4 1 2 0 -0.0007 7 0 0 0 5.94E+07 4.61E+07 - - - -0.8798 0.9354 221125_WJC_METTL3_EV_vs_WT_F06.04302.04302.2 0.00482 20-Oct A.ALGGNSSPSAK.D sp|P05387|RLA2_HUMAN 1 987.4985 0.74 75636 4302 2 987.496038 494.7565 60S acidic ribosomal protein P2 OS=Homo sapiens OX=9606 GN=RPLP2 PE=1 SV=1 8.8 1400.5 - 2.51E+06 - - - -2.5165 - 1.629 0.405 - 252.8 1 1 0 -0.0025 11 0 0 0 6.03E+07 8.11E+07 - - - 3.3516 0.966 221125_WJC_METTL3_EV_vs_WT_F06.04307.04307.2 0.0282 12-Jun V.MDVHDGK.V sp|P02533|K1C14_HUMAN 1 800.3487 16.69 75639 4307 2 800.347808 401.1816 "Keratin, type I cytoskeletal 14 OS=Homo sapiens OX=9606 GN=KRT14 PE=1 SV=4" 5.19 1401 - 1.94E+07 - - - -1.0995 - 1.377 0.411 - 134.4 1 1 0 -0.0009 7 0 0 0 4.59E+08 2.75E+07 - - - 3.09 0.9923 221125_WJC_METTL3_EV_vs_WT_F06.04308.04308.2 0.11 12-Aug R.KTYVTPR.R "sp|P46781|RS9_HUMAN,tr|C9JM19|C9JM19_HUMAN,tr|B5MCT8|B5MCT8_HUMAN,tr|F2Z3C0|F2Z3C0_HUMAN,tr|A8MXK4|A8MXK4_HUMAN" 5 863.4865 1.2 75640 4308 2 863.484668 432.7505 40S ribosomal protein S9 OS=Homo sapiens OX=9606 GN=RPS9 PE=1 SV=3 9.99 1401.1 - 5.35E+06 - - - -2.1239 - 1.552 0.133 - 299.2 1 2 0 -0.0018 7 0 0 0 1.19E+08 9.89E+07 - - - 1.4155 0.9997 221125_WJC_METTL3_EV_vs_WT_F06.04309.04309.2 0.000586 16-Sep K.QESTVATER.Q sp|Q9H307|PININ_HUMAN 1 1019.4884 1.81 75641 4309 2 1019.487136 510.7515 Pinin OS=Homo sapiens OX=9606 GN=PNN PE=1 SV=5 4.53 1401.2 - 1.53E+06 - - - -1.1937 - 2.014 0.39 - 396 1 2 0 -0.0012 9 0 0 0 1.84E+08 1.02E+08 - - - 3.9467 0.9975 221125_WJC_METTL3_EV_vs_WT_F06.04312.04312.2 0.0699 14-Aug K.EQGQNLAR[166.11].Q "sp|A6NIZ1|RP1BL_HUMAN,sp|P62834|RAP1A_HUMAN,sp|P61224|RAP1B_HUMAN,tr|F5H7Y6|F5H7Y6_HUMAN,tr|E7ESV4|E7ESV4_HUMAN,tr|F5GX62|F5GX62_HUMAN,tr|B7ZB78|B7ZB78_HUMAN,tr|F5GZG1|F5GZG1_HUMAN,tr|F5H823|F5H823_HUMAN" 9 924.4653 1.22 75643 4312 2 924.463919 463.2399 Ras-related protein Rap-1b-like protein OS=Homo sapiens OX=9606 PE=2 SV=1 6.1 1401.4 - 1.28E+07 - - - -1.4538 - 1.563 0.211 - 368.5 1 2 0 -0.0013 8 0 0 0 3.83E+08 3.14E+08 - - - 1.946 0.9997 221125_WJC_METTL3_EV_vs_WT_F06.04314.04314.2 0.000375 16-Oct K.QGVTEAAEK.T "sp|O76070|SYUG_HUMAN,sp|Q16143|SYUB_HUMAN,tr|F8W754|F8W754_HUMAN,tr|G4Y816|G4Y816_HUMAN" 4 931.4611 1.48 75644 4314 2 931.460069 466.7378 Gamma-synuclein OS=Homo sapiens OX=9606 GN=SNCG PE=1 SV=2 4.53 1401.7 - 1.08E+07 - - - -1.08 - 2.068 0.393 - 483.1 1 2 0 -0.001 9 0 0 0 2.32E+09 1.56E+09 - - - 4.0454 0.9999 221125_WJC_METTL3_EV_vs_WT_F06.04316.04316.2 0.000136 16-Sep K.VIAHSEYQK[136.11].S "sp|P49914|MTHFS_HUMAN,tr|A0A0A6YYL1|A0A0A6YYL1_HUMAN,tr|A0A0U1RR23|A0A0U1RR23_HUMAN,tr|A0A0U1RQM3|A0A0U1RQM3_HUMAN" 4 1081.5648 14.63 75646 4316 2 1081.564277 541.7897 5-formyltetrahydrofolate cyclo-ligase OS=Homo sapiens OX=9606 GN=MTHFS PE=1 SV=2 6.72 1401.8 - 1.18E+06 - - - -0.4457 - 1.975 0.477 - 281.5 1 2 0 -0.0005 9 0 0 0 2.00E+08 1.36E+07 - - - 4.5329 0.9042 221125_WJC_METTL3_EV_vs_WT_F06.04317.04317.2 1.03 12-May R.QQFNSGR.D sp|O95104|SCAF4_HUMAN 1 835.3937 1.08 75647 4317 2 835.392141 418.7041 SR-related and CTD-associated factor 4 OS=Homo sapiens OX=9606 GN=SCAF4 PE=1 SV=3 9.75 1401.9 - 1.10E+06 - - - -1.8231 - 1.025 0.074 - 132.3 2 2 0 -0.0015 7 0 0 0 2.89E+07 2.66E+07 - - - -0.4691 0.9994 221125_WJC_METTL3_EV_vs_WT_F06.04320.04320.2 0.0156 14-Sep K.K[136.11]VGDDIAK[136.11].A sp|P30050|RL12_HUMAN 1 860.4938 1.41 75648 4320 2 860.492302 431.2542 60S ribosomal protein L12 OS=Homo sapiens OX=9606 GN=RPL12 PE=1 SV=1 5.96 1402.3 - 6.92E+06 - - - -1.778 - 1.937 0.344 - 266.2 1 2 0 -0.0015 8 0 0 0 6.15E+09 4.35E+09 - - - 3.5753 0.9999 221125_WJC_METTL3_EV_vs_WT_F06.04322.04322.2 0.000137 16-Oct K.MEGHEAMER.L "sp|Q8WXI9|P66B_HUMAN,tr|A0A0U1RR34|A0A0U1RR34_HUMAN,tr|A0A0U1RRM1|A0A0U1RRM1_HUMAN,tr|A0A0U1RRK3|A0A0U1RRK3_HUMAN" 4 1088.4379 2.58 75650 4322 2 1088.436373 545.2262 Transcriptional repressor p66-beta OS=Homo sapiens OX=9606 GN=GATAD2B PE=1 SV=1 4.75 1402.4 - 641125 - - - -1.4158 - 1.962 0.572 - 456.1 1 2 0 -0.0015 9 0 0 0 5.53E+07 2.14E+07 - - - 5.2151 0.9998 221125_WJC_METTL3_EV_vs_WT_F06.04324.04324.2 5.62E-05 16-Oct K.MEGHEAMER[166.11].L "sp|Q8WXI9|P66B_HUMAN,tr|A0A0U1RR34|A0A0U1RR34_HUMAN,tr|A0A0U1RRM1|A0A0U1RRM1_HUMAN,tr|A0A0U1RRK3|A0A0U1RRK3_HUMAN" 4 1098.4462 2.58 75652 4324 2 1098.444213 550.2304 Transcriptional repressor p66-beta OS=Homo sapiens OX=9606 GN=GATAD2B PE=1 SV=1 4.75 1402.7 - 293344 - - - -1.7944 - 1.734 0.594 - 440.7 1 2 0 -0.002 9 0 0 0 5.53E+07 2.14E+07 - - - 5.0201 0.9998 221125_WJC_METTL3_EV_vs_WT_F06.04327.04327.2 4.40E-05 18-Oct K.LDDANDAGGR[166.11].N sp|P11388|TOP2A_HUMAN 1 1012.4449 0.86 75654 4327 2 1012.44354 507.2297 DNA topoisomerase 2-alpha OS=Homo sapiens OX=9606 GN=TOP2A PE=1 SV=3 3.93 1403.1 - 3.35E+06 - - - -1.365 - 2.354 0.482 - 285.5 1 2 0 -0.0014 10 0 0 0 9.71E+07 1.13E+08 - - - 4.9903 0.9985 221125_WJC_METTL3_EV_vs_WT_F06.04329.04329.2 0.0104 16-Oct K.QGVTEAAEK[136.11].T "sp|O76070|SYUG_HUMAN,sp|Q16143|SYUB_HUMAN,tr|F8W754|F8W754_HUMAN,tr|G4Y816|G4Y816_HUMAN" 4 939.4753 1.48 75655 4329 2 939.472746 470.7449 Gamma-synuclein OS=Homo sapiens OX=9606 GN=SNCG PE=1 SV=2 4.53 1403.3 - 3.40E+07 - - - -2.6919 - 2.008 0.286 - 469 1 2 0 -0.0025 9 0 0 0 2.32E+09 1.57E+09 - - - 3.1695 0.9994 221125_WJC_METTL3_EV_vs_WT_F06.04330.04330.2 0.0143 14-Oct K.KVGDDIAK.A sp|P30050|RL12_HUMAN 1 844.4654 1.41 75656 4330 2 844.464198 423.24 60S ribosomal protein L12 OS=Homo sapiens OX=9606 GN=RPL12 PE=1 SV=1 5.96 1403.3 - 2.35E+07 - - - -1.4613 - 2.111 0.271 - 360.5 1 2 0 -0.0012 8 0 0 0 6.15E+09 4.35E+09 - - - 3.2956 0.9992 221125_WJC_METTL3_EV_vs_WT_F06.04333.04333.2 0.0509 12-Jul R.QSPSYGR.H "sp|Q86YZ3|HORN_HUMAN,sp|Q86YZ3|HORN_HUMAN,sp|Q86YZ3|HORN_HUMAN,sp|Q86YZ3|HORN_HUMAN" 4 793.3719 345.36 75659 4333 2 793.371242 397.6932 Hornerin OS=Homo sapiens OX=9606 GN=HRNR PE=1 SV=2 8.75 1403.4 - 8.93E+06 - - - -0.7865 - 1.381 0.355 - 235.1 1 2 0 -0.0006 7 0 0 0 3.97E+09 1.15E+07 - - - 2.6857 0.9997 221125_WJC_METTL3_EV_vs_WT_F06.04334.04334.2 0.000799 18-Oct K.LDDANDAGGR.N sp|P11388|TOP2A_HUMAN 1 1002.4367 0.89 75660 4334 2 1002.434394 502.2256 DNA topoisomerase 2-alpha OS=Homo sapiens OX=9606 GN=TOP2A PE=1 SV=3 3.93 1403.5 - 4.50E+06 - - - -2.2525 - 2.205 0.494 - 349.7 1 2 0 -0.0023 10 0 0 0 9.65E+07 1.08E+08 - - - 4.8961 0.999 221125_WJC_METTL3_EV_vs_WT_F06.04338.04338.2 0.0131 14-Jun K.SSTPEEVK[136.11].K "sp|P23528|COF1_HUMAN,tr|E9PP50|E9PP50_HUMAN,tr|G3V1A4|G3V1A4_HUMAN,tr|E9PQB7|E9PQB7_HUMAN,tr|E9PK25|E9PK25_HUMAN,tr|E9PLJ3|E9PLJ3_HUMAN,tr|E9PS23|E9PS23_HUMAN" 7 883.4378 1.36 75662 4338 2 883.436662 442.7262 Cofilin-1 OS=Homo sapiens OX=9606 GN=CFL1 PE=1 SV=3 4.53 1404 - 2.99E+07 - - - -1.3187 - 1.362 0.366 - 160.8 1 2 0 -0.0012 8 0 0 0 2.88E+09 2.12E+09 - - - 2.6757 0.9977 221125_WJC_METTL3_EV_vs_WT_F06.04355.04355.2 0.0179 16-Jul K.FSSQQAATK.Q sp|O75475|PSIP1_HUMAN 1 966.4771 0.85 75673 4355 2 966.474581 484.2458 PC4 and SFRS1-interacting protein OS=Homo sapiens OX=9606 GN=PSIP1 PE=1 SV=1 8.75 1405.7 - 2.19E+06 - - - -2.565 - 1.488 0.337 - 104 1 2 0 -0.0025 9 0 0 0 2.10E+08 2.48E+08 - - - 2.6791 0.9986 221125_WJC_METTL3_EV_vs_WT_F06.04363.04363.2 0.0307 16-Oct R.VTQVENEEK[136.11].L "sp|O14524|NEMP1_HUMAN,tr|G3V5K2|G3V5K2_HUMAN" 2 1082.5335 1.12 75675 4363 2 1082.530593 542.274 Nuclear envelope integral membrane protein 1 OS=Homo sapiens OX=9606 GN=NEMP1 PE=1 SV=2 4.25 1406.9 - 1.35E+06 - - - -2.7029 - 1.927 0.317 - 384.3 1 2 0 -0.0029 9 0 0 0 5.02E+07 4.50E+07 - - - 3.2792 0.9284 221125_WJC_METTL3_EV_vs_WT_F06.04376.04376.2 2.3 12-May R.SYSPDGK[136.11].E "sp|P43243|MATR3_HUMAN,tr|B3KM87|B3KM87_HUMAN,tr|A8MXP9|A8MXP9_HUMAN,tr|A0A0R4J2E8|A0A0R4J2E8_HUMAN,tr|D6REM6|D6REM6_HUMAN" 5 760.3483 0.001 75680 4376 2 760.346628 381.1814 Matrin-3 OS=Homo sapiens OX=9606 GN=MATR3 PE=1 SV=2 5.55 1408.5 - 4.81E+06 - - - -2.1779 - 0.909 0.155 - 101.1 1 2 0 -0.0017 7 0 0 0 0.00E+00 2.87E+08 - - - -0.117 0.9996 221125_WJC_METTL3_EV_vs_WT_F06.04377.04377.2 6.57E-05 20-Nov R.GEATATDAEAR[166.11].E sp|O95613|PCNT_HUMAN 1 1100.4974 1.23 75681 4377 2 1100.49479 551.256 Pericentrin OS=Homo sapiens OX=9606 GN=PCNT PE=1 SV=4 4.14 1408.6 - 357746 - - - -2.3271 - 1.937 0.501 - 320.7 1 2 0 -0.0026 11 0 0 0 1.41E+07 1.14E+07 - - - 4.5291 0.9997 221125_WJC_METTL3_EV_vs_WT_F06.04378.04378.2 0.00152 14-Jul R.YGNPSENR[166.11].S sp|Q4VCS5|AMOT_HUMAN 1 945.418 1.25 75682 4378 2 945.417347 473.7163 Angiomotin OS=Homo sapiens OX=9606 GN=AMOT PE=1 SV=1 6 1408.7 - 2.33E+06 - - - -0.6674 - 1.526 0.476 - 171.7 1 2 0 -0.0006 8 0 0 0 1.17E+08 9.33E+07 - - - 3.8312 0.9999 221125_WJC_METTL3_EV_vs_WT_F06.04380.04380.2 0.0011 18-Dec K.C[160.03]VEENNGVAK.H "sp|Q15758|AAAT_HUMAN,tr|M0QXM4|M0QXM4_HUMAN,tr|M0QX44|M0QX44_HUMAN" 3 1118.5026 1.09 75683 4380 2 1118.501004 560.2586 Neutral amino acid transporter B(0) OS=Homo sapiens OX=9606 GN=SLC1A5 PE=1 SV=2 4.53 1408.9 - 2.68E+06 - - - -1.4475 - 2.157 0.553 - 379.4 1 2 0 -0.0016 10 0 0 0 4.73E+07 4.34E+07 - - - 5.2707 0.9994 221125_WJC_METTL3_EV_vs_WT_F06.04386.04386.2 0.012 14-Aug R.STDPVTTK[136.11].E "sp|Q9Y520|PRC2C_HUMAN,tr|E7EPN9|E7EPN9_HUMAN,tr|H7C5N8|H7C5N8_HUMAN,tr|A0A2R8Y7F4|A0A2R8Y7F4_HUMAN,tr|A0A2R8YET2|A0A2R8YET2_HUMAN" 5 855.4429 2.18 75686 4386 2 855.441794 428.7287 Protein PRRC2C OS=Homo sapiens OX=9606 GN=PRRC2C PE=1 SV=4 5.55 1409.6 - 1.00E+07 - - - -1.3081 - 1.596 0.364 - 372.8 1 2 0 -0.0011 8 0 0 0 5.73E+08 2.63E+08 - - - 3.1391 0.9966 221125_WJC_METTL3_EV_vs_WT_F06.04388.04388.2 0.016 14-Jul K.TDYEGQAK.K "sp|Q53H12|AGK_HUMAN,tr|E9PC15|E9PC15_HUMAN,tr|A0A3B3ITV0|A0A3B3ITV0_HUMAN,tr|A0A3B3IS09|A0A3B3IS09_HUMAN,tr|A0A3B3ITX7|A0A3B3ITX7_HUMAN,tr|E9PG39|E9PG39_HUMAN,tr|A0A3B3ITD0|A0A3B3ITD0_HUMAN,tr|A0A3B3IUC9|A0A3B3IUC9_HUMAN,tr|A0A3B3ISY9|A0A3B3ISY9_HUMAN,tr|A0A3B3ISZ0|A0A3B3ISZ0_HUMAN" 10 910.4032 1.04 75688 4388 2 910.401564 456.2089 "Acylglycerol kinase, mitochondrial OS=Homo sapiens OX=9606 GN=AGK PE=1 SV=2" 4.37 1409.7 - 3.72E+06 - - - -1.8256 - 1.403 0.247 - 218.8 1 2 0 -0.0017 8 0 0 0 7.73E+07 7.47E+07 - - - 1.8861 0.9991 221125_WJC_METTL3_EV_vs_WT_F06.04389.04389.2 0.00379 14-Aug K.TDYEGQAK[136.11].K "sp|Q53H12|AGK_HUMAN,tr|E9PC15|E9PC15_HUMAN,tr|A0A3B3ITV0|A0A3B3ITV0_HUMAN,tr|A0A3B3IS09|A0A3B3IS09_HUMAN,tr|A0A3B3ITX7|A0A3B3ITX7_HUMAN,tr|E9PG39|E9PG39_HUMAN,tr|A0A3B3ITD0|A0A3B3ITD0_HUMAN,tr|A0A3B3IUC9|A0A3B3IUC9_HUMAN,tr|A0A3B3ISY9|A0A3B3ISY9_HUMAN,tr|A0A3B3ISZ0|A0A3B3ISZ0_HUMAN" 10 918.4174 1.04 75689 4389 2 918.415295 460.216 "Acylglycerol kinase, mitochondrial OS=Homo sapiens OX=9606 GN=AGK PE=1 SV=2" 4.37 1409.8 - 3.66E+06 - - - -2.3203 - 1.6 0.412 - 326.5 1 2 0 -0.0021 8 0 0 0 7.74E+07 7.43E+07 - - - 3.5009 0.9997 221125_WJC_METTL3_EV_vs_WT_F06.04397.04397.2 0.00585 16-Aug K.FSSQQAATK[136.11].Q sp|O75475|PSIP1_HUMAN 1 974.4913 0.84 75693 4397 2 974.49051 488.2529 PC4 and SFRS1-interacting protein OS=Homo sapiens OX=9606 GN=PSIP1 PE=1 SV=1 8.75 1410.8 - 6.30E+06 - - - -0.7696 - 1.678 0.424 - 137.1 1 2 0 -0.0008 9 0 0 0 2.10E+08 2.50E+08 - - - 3.6699 0.9983 221125_WJC_METTL3_EV_vs_WT_F06.04398.04398.2 0.00535 14-Jul R.QEAIAQNR.R sp|Q6P2Q9|PRP8_HUMAN 1 928.4726 0.82 75694 4398 2 928.472693 465.2436 Pre-mRNA-processing-splicing factor 8 OS=Homo sapiens OX=9606 GN=PRPF8 PE=1 SV=2 6 1410.8 - 4.34E+06 - - - 0.0539 - 1.422 0.244 - 193.7 1 2 0 0.0001 8 0 0 0 9.56E+07 1.17E+08 - - - 1.905 0.9984 221125_WJC_METTL3_EV_vs_WT_F06.04403.04403.2 0.00463 14-Aug R.QEAIAQNR[166.11].R sp|Q6P2Q9|PRP8_HUMAN 1 938.4809 0.84 75697 4403 2 938.479244 470.2477 Pre-mRNA-processing-splicing factor 8 OS=Homo sapiens OX=9606 GN=PRPF8 PE=1 SV=2 6 1411.4 - 1.67E+06 - - - -1.7784 - 1.559 0.288 - 352.3 1 2 0 -0.0017 8 0 0 0 9.96E+07 1.18E+08 - - - 2.5069 0.9953 221125_WJC_METTL3_EV_vs_WT_F06.04405.04405.2 0.0736 14-Jul R.NQQTIGAR.K "sp|Q7L1Q6|BZW1_HUMAN,tr|C9IZ80|C9IZ80_HUMAN" 2 886.4621 0.18 75698 4405 2 886.461477 444.2383 Basic leucine zipper and W2 domain-containing protein 1 OS=Homo sapiens OX=9606 GN=BZW1 PE=1 SV=1 9.75 1411.6 - 9.06E+06 - - - -0.678 - 1.468 0.134 - 300.3 1 2 0 -0.0006 8 0 0 0 1.09E+08 5.97E+08 - - - 1.1884 0.9996 221125_WJC_METTL3_EV_vs_WT_F06.04408.04408.2 5.45E-05 20-Oct R.GAC[160.03]AGSEDAVK.A "sp|Q13813|SPTN1_HUMAN,tr|A0A0D9SF54|A0A0D9SF54_HUMAN,tr|A0A0D9SGF6|A0A0D9SGF6_HUMAN" 3 1063.4604 1.38 75701 4408 2 1063.459361 532.7375 "Spectrin alpha chain, non-erythrocytic 1 OS=Homo sapiens OX=9606 GN=SPTAN1 PE=1 SV=3" 4.37 1411.9 - 1.56E+06 - - - -0.9996 - 1.889 0.358 - 306.7 1 2 0 -0.0011 11 0 0 0 6.65E+07 4.82E+07 - - - 3.4055 0.9955 221125_WJC_METTL3_EV_vs_WT_F06.04409.04409.2 0.0646 16-Aug K.ETQSPEQVK[136.11].S "sp|Q9NYF8|BCLF1_HUMAN,tr|E9PKI6|E9PKI6_HUMAN,tr|A0A1W2PQ43|A0A1W2PQ43_HUMAN,tr|E9PK91|E9PK91_HUMAN,tr|E9PK09|E9PK09_HUMAN,tr|E9PQN2|E9PQN2_HUMAN" 6 1052.523 4.49 75702 4409 2 1052.521228 527.2688 Bcl-2-associated transcription factor 1 OS=Homo sapiens OX=9606 GN=BCLAF1 PE=1 SV=2 4.53 1412 - 1.23E+06 - - - -1.6399 - 1.344 0.227 - 241.8 1 2 0 -0.0017 9 0 0 0 2.87E+09 6.38E+08 - - - 1.5724 0.9987 221125_WJC_METTL3_EV_vs_WT_F06.04412.04412.2 0.0479 14-Sep R.NQQTIGAR[166.11].K "sp|Q7L1Q6|BZW1_HUMAN,tr|C9IZ80|C9IZ80_HUMAN" 2 896.4703 0.07 75704 4412 2 896.469258 449.2425 Basic leucine zipper and W2 domain-containing protein 1 OS=Homo sapiens OX=9606 GN=BZW1 PE=1 SV=1 9.75 1412.3 - 9.96E+06 - - - -1.2159 - 1.802 0.209 - 545.3 1 2 0 -0.0011 8 0 0 0 1.10E+08 1.62E+09 - - - 2.3604 0.9998 221125_WJC_METTL3_EV_vs_WT_F06.04415.04415.2 0.0639 16-Oct K.EAAEQDVEK.K "sp|P26373|RL13_HUMAN,tr|J3KS98|J3KS98_HUMAN" 2 1017.4615 1.21 75706 4415 2 1017.460578 509.738 60S ribosomal protein L13 OS=Homo sapiens OX=9606 GN=RPL13 PE=1 SV=4 4 1412.6 - 4.80E+06 - - - -0.8757 - 2.07 0.393 - 542.2 1 2 0 -0.0009 9 0 0 0 4.41E+08 3.66E+08 - - - 4.0483 0.9261 221125_WJC_METTL3_EV_vs_WT_F06.04416.04416.2 1.2 16-Jul Y.ALTGDEVK[136.11]K[136.11].L "sp|P62701|RS4X_HUMAN,sp|P22090|RS4Y1_HUMAN,sp|Q8TD47|RS4Y2_HUMAN,tr|C9JEH7|C9JEH7_HUMAN" 4 975.5572 0.82 75707 4416 2 975.556894 488.7859 "40S ribosomal protein S4, X isoform OS=Homo sapiens OX=9606 GN=RPS4X PE=1 SV=2" 6.11 1412.6 - 2.68E+06 - - - -0.2737 - 1.385 0.29 - 123.4 1 1 0 -0.0003 9 0 0 0 3.45E+07 4.23E+07 - - - 2.1251 0.9734 221125_WJC_METTL3_EV_vs_WT_F06.04422.04422.2 0.000692 18-Aug R.RAEQDSTTVA.A "sp|Q86U44|MTA70_HUMAN,tr|F5H6D8|F5H6D8_HUMAN,tr|H0YFV6|H0YFV6_HUMAN,tr|B4DTN4|B4DTN4_HUMAN" 4 1076.5098 0.02 75711 4422 2 1076.50939 539.2622 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 4.37 1413.3 - 1.35E+06 - - - -0.3957 - 1.555 0.387 - 241.7 1 1 0 -0.0004 10 0 0 0 3.92E+07 1.62E+09 - - - 3.1315 0.9924 221125_WJC_METTL3_EV_vs_WT_F06.04430.04430.2 0.228 14-Jul K.QPASQLQK.Q "sp|Q16891|MIC60_HUMAN,tr|B9A067|B9A067_HUMAN,tr|A0A087WYS0|A0A087WYS0_HUMAN,tr|D6RAW4|D6RAW4_HUMAN,tr|C9J406|C9J406_HUMAN,tr|H7C463|H7C463_HUMAN" 6 898.4872 1.32 75716 4430 2 898.486471 450.2509 MICOS complex subunit MIC60 OS=Homo sapiens OX=9606 GN=IMMT PE=1 SV=1 8.75 1414 - 7.75E+06 - - - -0.8448 - 1.407 0.111 - 274.7 1 2 0 -0.0008 8 0 0 0 1.63E+09 1.24E+09 - - - 0.8904 0.967 221125_WJC_METTL3_EV_vs_WT_F06.04431.04431.2 3.98 12-Jul K.KDEEVLK.K "sp|Q13838|DX39B_HUMAN,sp|O00148|DX39A_HUMAN,tr|K7EPJ3|K7EPJ3_HUMAN,tr|A0A140TA18|A0A140TA18_HUMAN,tr|F6UJC5|F6UJC5_HUMAN,tr|F6TRA5|F6TRA5_HUMAN,tr|F6WLT2|F6WLT2_HUMAN,tr|Q5STU3|Q5STU3_HUMAN,tr|A0A140T973|A0A140T973_HUMAN,tr|A0A140T9K2|A0A140T9K2_HUMAN,tr|A0A140T9X9|A0A140T9X9_HUMAN,tr|F6R6M7|F6R6M7_HUMAN,tr|F6QYI9|F6QYI9_HUMAN,tr|A0A140T996|A0A140T996_HUMAN,tr|A0A0G2JJL7|A0A0G2JJL7_HUMAN,tr|A0A140T9L4|A0A140T9L4_HUMAN,tr|A0A140T9N3|A0A140T9N3_HUMAN,tr|A0A0G2JJZ9|A0A0G2JJZ9_HUMAN,tr|A0A140T9K1|A0A140T9K1_HUMAN,tr|K7EQN7|K7EQN7_HUMAN,tr|A0A140T9X3|A0A140T9X3_HUMAN,tr|F6S4E6|F6S4E6_HUMAN,tr|A0A0A0MT12|A0A0A0MT12_HUMAN,tr|A0A0D9SEM9|A0A0D9SEM9_HUMAN" 24 859.4651 1.14 75717 4431 2 859.463078 430.7398 Spliceosome RNA helicase DDX39B OS=Homo sapiens OX=9606 GN=DDX39B PE=1 SV=1 4.68 1414.1 - 2.03E+06 - - - -2.3503 - 1.302 0.083 - 159.4 1 2 0 -0.002 7 0 0 0 2.86E+07 2.52E+07 - - - 0.4896 0.9975 221125_WJC_METTL3_EV_vs_WT_F06.04432.04432.2 0.176 14-Jul K.QPASQLQK[136.11].Q "sp|Q16891|MIC60_HUMAN,tr|B9A067|B9A067_HUMAN,tr|A0A087WYS0|A0A087WYS0_HUMAN,tr|D6RAW4|D6RAW4_HUMAN,tr|C9J406|C9J406_HUMAN,tr|H7C463|H7C463_HUMAN" 6 906.5014 1.32 75718 4432 2 906.500412 454.258 MICOS complex subunit MIC60 OS=Homo sapiens OX=9606 GN=IMMT PE=1 SV=1 8.75 1414.1 - 7.50E+06 - - - -1.123 - 1.418 0.233 - 208.3 1 2 0 -0.001 8 0 0 0 1.63E+09 1.23E+09 - - - 1.8149 0.9977 221125_WJC_METTL3_EV_vs_WT_F06.04449.04449.2 0.0312 14-Jul K.VSNSGITR[166.11].V sp|P50991|TCPD_HUMAN 1 842.4485 0.32 75729 4449 2 842.44692 422.2316 T-complex protein 1 subunit delta OS=Homo sapiens OX=9606 GN=CCT4 PE=1 SV=4 9.72 1416.1 - 5.84E+06 - - - -1.9348 - 1.537 0.262 - 126.4 1 2 0 -0.0016 8 0 0 0 7.19E+07 2.22E+08 - - - 2.272 0.8151 221125_WJC_METTL3_EV_vs_WT_F06.04450.04450.2 0.834 12-Jul K.LK[136.11]EEISK[136.11].M "sp|P38646|GRP75_HUMAN,tr|A0A7I2V2S7|A0A7I2V2S7_HUMAN,tr|A0A7I2V2G2|A0A7I2V2G2_HUMAN,tr|A0A7I2V3F7|A0A7I2V3F7_HUMAN,tr|A0A7I2YQB2|A0A7I2YQB2_HUMAN,tr|D6RCD7|D6RCD7_HUMAN" 6 861.5142 0.41 75730 4450 2 861.512951 431.7644 "Stress-70 protein, mitochondrial OS=Homo sapiens OX=9606 GN=HSPA9 PE=1 SV=2" 6.14 1416.1 - 5.16E+06 - - - -1.4892 - 1.692 0.001 - 159.8 4 2 1 -0.0013 7 0 0 0 7.04E+08 1.71E+09 - - - 0.4454 0.9976 221125_WJC_METTL3_EV_vs_WT_F06.04452.04452.2 0.149 12-Aug R.NFQANTK[136.11].G "sp|O75937|DNJC8_HUMAN,tr|S4R3J5|S4R3J5_HUMAN" 2 829.4174 0.47 75732 4452 2 829.415943 415.716 DnaJ homolog subfamily C member 8 OS=Homo sapiens OX=9606 GN=DNAJC8 PE=1 SV=2 8.75 1416.2 - 3.29E+06 - - - -1.7157 - 1.338 0.29 - 308.1 1 2 0 -0.0014 7 0 0 0 3.98E+07 8.52E+07 - - - 2.1051 0.9952 221125_WJC_METTL3_EV_vs_WT_F06.04458.04458.2 0.00292 14-Aug K.SNGDLSPK[136.11].G sp|P49006|MRP_HUMAN 1 824.4119 0.74 75737 4458 2 824.410842 413.2132 MARCKS-related protein OS=Homo sapiens OX=9606 GN=MARCKSL1 PE=1 SV=2 5.55 1416.8 - 1.55E+07 - - - -1.3403 - 1.762 0.087 - 316.3 1 2 0 -0.0011 8 0 0 0 4.51E+08 6.10E+08 - - - 1.3916 0.9897 221125_WJC_METTL3_EV_vs_WT_F06.04461.04461.2 1.2 14-Aug K.SSTPVPSK.Q "sp|Q9H8V3|ECT2_HUMAN,tr|H7C3G1|H7C3G1_HUMAN" 2 801.4232 0.92 75739 4461 2 801.424073 401.7189 Protein ECT2 OS=Homo sapiens OX=9606 GN=ECT2 PE=1 SV=4 8.47 1417.1 - 1.43E+06 - - - 1.0481 - 1.368 0.111 - 285.6 1 2 0 0.0008 8 0 0 0 5.14E+07 5.57E+07 - - - 0.8056 0.9981 221125_WJC_METTL3_EV_vs_WT_F06.04470.04470.2 0.248 12-Aug R.HYGPGVR.F sp|Q6ZVX7|FBX50_HUMAN 1 784.398 0.7 75746 4470 2 784.396813 393.2063 F-box only protein 50 OS=Homo sapiens OX=9606 GN=NCCRP1 PE=1 SV=1 8.75 1418.1 - 5.13E+06 - - - -1.54 - 1.368 0.294 - 188.7 1 2 0 -0.0012 7 0 0 0 2.13E+08 3.05E+08 - - - 2.205 0.9 221125_WJC_METTL3_EV_vs_WT_F06.04471.04471.2 6.15 14-Jul R.NFNQEGTK.L "sp|P52732|KIF11_HUMAN,tr|A0A7I2V3A9|A0A7I2V3A9_HUMAN" 2 936.4301 4.39 75747 4471 2 936.432254 469.2223 Kinesin-like protein KIF11 OS=Homo sapiens OX=9606 GN=KIF11 PE=1 SV=2 6 1418.2 - 2.67E+06 - - - 2.2895 - 1.078 0.064 - 173.4 1 2 0 0.0021 8 0 0 0 5.63E+09 1.28E+09 - - - -0.2604 0.9957 221125_WJC_METTL3_EV_vs_WT_F06.04473.04473.2 0.184 12-Jun K.EQVAHIR.A "sp|Q9Y2H1|ST38L_HUMAN,tr|F5H277|F5H277_HUMAN" 2 851.4614 4.22 75749 4473 2 851.460291 426.738 Serine\threonine-protein kinase 38-like OS=Homo sapiens OX=9606 GN=STK38L PE=1 SV=3 6.85 1418.3 - 2.20E+06 - - - -1.2437 - 1.431 0.169 - 199.1 1 2 0 -0.0011 7 0 0 0 3.65E+08 8.64E+07 - - - 1.4244 0.9635 221125_WJC_METTL3_EV_vs_WT_F06.04474.04474.2 0.101 16-Sep K.VKDAVQAVK.R sp|Q5SWX8|ODR4_HUMAN 1 956.5655 2.4 75750 4474 2 956.564003 479.29 Protein odr-4 homolog OS=Homo sapiens OX=9606 GN=ODR4 PE=1 SV=1 8.56 1418.3 - 2.19E+06 - - - -1.5451 - 1.326 0.256 - 168 1 2 1 -0.0015 9 0 0 0 5.77E+07 2.40E+07 - - - 1.7477 0.9996 221125_WJC_METTL3_EV_vs_WT_F06.04478.04478.2 8.01E-06 18-Nov K.LTEDEEGNAK[136.11].L "sp|O00330|ODPX_HUMAN,tr|H0YD97|H0YD97_HUMAN" 2 1112.5077 0.06 75754 4478 2 1112.504713 557.2611 "Pyruvate dehydrogenase protein X component, mitochondrial OS=Homo sapiens OX=9606 GN=PDHX PE=1 SV=3" 4 1418.7 - 908509 - - - -2.6831 - 2.28 0.506 - 357.4 1 2 0 -0.003 10 0 0 0 2.67E+06 4.52E+07 - - - 5.0779 0.9997 221125_WJC_METTL3_EV_vs_WT_F06.04480.04480.2 0.0131 16-Aug K.EAAEQDVEK[136.11].K "sp|P26373|RL13_HUMAN,tr|J3KS98|J3KS98_HUMAN" 2 1025.4757 1.21 75755 4480 2 1025.474677 513.7451 60S ribosomal protein L13 OS=Homo sapiens OX=9606 GN=RPL13 PE=1 SV=4 4 1418.9 - 1.00E+07 - - - -0.9674 - 1.837 0.405 - 362.5 1 2 0 -0.001 9 0 0 0 4.42E+08 3.66E+08 - - - 3.7914 0.9975 221125_WJC_METTL3_EV_vs_WT_F06.04484.04484.2 0.0191 14-Jul R.NFNQEGTK[136.11].L "sp|P52732|KIF11_HUMAN,tr|A0A7I2V3A9|A0A7I2V3A9_HUMAN" 2 944.4443 4.39 75758 4484 2 944.442964 473.2294 Kinesin-like protein KIF11 OS=Homo sapiens OX=9606 GN=KIF11 PE=1 SV=2 6 1419.2 - 4.00E+06 - - - -1.4252 - 1.283 0.291 - 174 1 2 0 -0.0013 8 0 0 0 5.63E+09 1.28E+09 - - - 1.9415 0.9934 221125_WJC_METTL3_EV_vs_WT_F06.04485.04485.2 0.521 14-Jul K.GTTEEVC[160.03]R[166.11].L "sp|Q99613|EIF3C_HUMAN,sp|B5ME19|EIFCL_HUMAN" 2 960.421 0.29 75759 4485 2 960.417656 481.2178 Eukaryotic translation initiation factor 3 subunit C OS=Homo sapiens OX=9606 GN=EIF3C PE=1 SV=1 4.53 1419.3 - 2.85E+06 - - - -3.4974 - 1.466 0.291 - 234.4 1 2 0 -0.0034 8 0 0 0 2.65E+07 9.24E+07 - - - 2.343 0.9989 221125_WJC_METTL3_EV_vs_WT_F06.04487.04487.2 0.000236 18-Oct K.GAATSVSNPR[166.11].G "sp|Q8NFW8|NEUA_HUMAN,tr|F5H296|F5H296_HUMAN" 2 968.4915 0.78 75761 4487 2 968.488245 485.253 N-acylneuraminate cytidylyltransferase OS=Homo sapiens OX=9606 GN=CMAS PE=1 SV=2 9.75 1419.5 - 1.56E+06 - - - -3.3382 - 2.064 0.412 - 481.9 1 2 0 -0.0032 10 0 0 0 3.89E+07 4.98E+07 - - - 4.1057 0.9927 221125_WJC_METTL3_EV_vs_WT_F06.04488.04488.2 0.000667 12-Jul K.C[160.03]NIC[160.03]GNR.F "sp|Q9NSC2|SALL1_HUMAN,sp|Q9BXA9|SALL3_HUMAN,tr|A0A087WXW6|A0A087WXW6_HUMAN,tr|A0A140TA74|A0A140TA74_HUMAN,tr|A0A140TA70|A0A140TA70_HUMAN,tr|H3BSM9|H3BSM9_HUMAN,tr|A9JR48|A9JR48_HUMAN" 7 892.3644 0.78 75762 4488 2 892.359285 447.1895 Sal-like protein 1 OS=Homo sapiens OX=9606 GN=SALL1 PE=1 SV=2 8.07 1419.5 - 2.67E+06 - - - -5.6815 - 1.706 0.425 - 354.3 1 2 0 -0.0051 7 0 0 0 4.19E+07 5.35E+07 - - - 3.8709 0.9707 221125_WJC_METTL3_EV_vs_WT_F06.04500.04500.2 1.36 14-Jul K.SSTPVPSK[136.11].Q "sp|Q9H8V3|ECT2_HUMAN,tr|H7C3G1|H7C3G1_HUMAN" 2 809.4374 0.94 75768 4500 2 809.436287 405.726 Protein ECT2 OS=Homo sapiens OX=9606 GN=ECT2 PE=1 SV=4 8.47 1420.9 - 1.34E+06 - - - -1.4158 - 1.3 0.044 - 216.1 1 2 0 -0.0011 8 0 0 0 4.93E+07 5.22E+07 - - - 0.1569 0.9991 221125_WJC_METTL3_EV_vs_WT_F06.04502.04502.2 0.00479 16-Oct K.AANVQEPEK.K sp|P56182|RRP1_HUMAN 1 984.4876 8.11 75769 4502 2 984.485505 493.2511 Ribosomal RNA processing protein 1 homolog A OS=Homo sapiens OX=9606 GN=RRP1 PE=1 SV=1 4.53 1421.2 - 552452 - - - -2.1524 - 1.594 0.395 - 305.3 1 2 0 -0.0021 9 0 0 0 1.20E+08 1.48E+07 - - - 3.3067 0.9996 221125_WJC_METTL3_EV_vs_WT_F06.04505.04505.2 0.00787 18-Sep K.EAPAQPAPEK.V "sp|Q15428|SF3A2_HUMAN,tr|K7EMT0|K7EMT0_HUMAN" 2 1036.5189 1.81 75770 4505 2 1036.518302 519.2667 Splicing factor 3A subunit 2 OS=Homo sapiens OX=9606 GN=SF3A2 PE=1 SV=2 4.53 1421.6 - 1.26E+06 - - - -0.6011 - 1.702 0.387 - 347.6 1 2 0 -0.0006 10 0 0 0 2.10E+08 1.16E+08 - - - 3.3836 0.9992 221125_WJC_METTL3_EV_vs_WT_F06.04507.04507.2 0.00577 18-Nov K.VQSGNINAAK[136.11].T "sp|P49368|TCPG_HUMAN,tr|E9PM09|E9PM09_HUMAN,tr|Q5SZW8|Q5SZW8_HUMAN,tr|E9PRC8|E9PRC8_HUMAN,tr|Q5SZX9|Q5SZX9_HUMAN,tr|Q5SZX6|Q5SZX6_HUMAN" 6 1008.5444 0.31 75772 4507 2 1008.542736 505.2795 T-complex protein 1 subunit gamma OS=Homo sapiens OX=9606 GN=CCT3 PE=1 SV=4 8.72 1421.7 - 3.83E+06 - - - -1.6083 - 1.841 0.312 - 317.4 1 2 0 -0.0016 10 0 0 0 9.99E+08 3.24E+09 - - - 3.0485 0.9841 221125_WJC_METTL3_EV_vs_WT_F06.04510.04510.2 0.0048 18-Dec A.TAASSSSLEK.S "sp|Q6S8J3|POTEE_HUMAN,sp|P63261|ACTG_HUMAN,sp|P68133|ACTS_HUMAN,sp|P62736|ACTA_HUMAN,sp|P68032|ACTC_HUMAN,sp|P60709|ACTB_HUMAN,sp|P63267|ACTH_HUMAN,tr|A0A804GS07|A0A804GS07_HUMAN,tr|E7EVS6|E7EVS6_HUMAN,tr|A0A6Q8PFE4|A0A6Q8PFE4_HUMAN,tr|A0A2R8YEA7|A0A2R8YEA7_HUMAN,tr|A0A804HKV3|A0A804HKV3_HUMAN,tr|A0A2R8Y793|A0A2R8Y793_HUMAN,tr|I3L4N8|I3L4N8_HUMAN,tr|A6NL76|A6NL76_HUMAN" 15 979.4822 1.34 75773 4510 2 979.481451 490.7484 POTE ankyrin domain family member E OS=Homo sapiens OX=9606 GN=POTEE PE=2 SV=3 5.66 1422.1 - 1.20E+06 - - - -0.7698 - 2.037 0.378 - 402.4 1 1 0 -0.0008 10 0 0 0 9.13E+07 6.82E+07 - - - 3.8186 0.9982 221125_WJC_METTL3_EV_vs_WT_F06.04516.04516.2 0.00234 18-Oct K.VQSGNINAAK.T "sp|P49368|TCPG_HUMAN,tr|E9PM09|E9PM09_HUMAN,tr|Q5SZW8|Q5SZW8_HUMAN,tr|E9PRC8|E9PRC8_HUMAN,tr|Q5SZX9|Q5SZX9_HUMAN,tr|Q5SZX6|Q5SZX6_HUMAN" 6 1000.5302 0.28 75777 4516 2 1000.52936 501.2724 T-complex protein 1 subunit gamma OS=Homo sapiens OX=9606 GN=CCT3 PE=1 SV=4 8.72 1422.7 - 3.11E+06 - - - -0.7976 - 1.979 0.135 - 285.6 1 2 0 -0.0008 10 0 0 0 8.80E+08 3.19E+09 - - - 1.9432 0.9955 221125_WJC_METTL3_EV_vs_WT_F06.04522.04522.2 0.000815 18-Nov K.GAATSVSNPR.G "sp|Q8NFW8|NEUA_HUMAN,tr|F5H296|F5H296_HUMAN" 2 958.4832 0.64 75780 4522 2 958.478504 480.2489 N-acylneuraminate cytidylyltransferase OS=Homo sapiens OX=9606 GN=CMAS PE=1 SV=2 9.75 1423.4 - 2.35E+06 - - - -4.9078 - 2.19 0.345 - 526.3 1 2 0 -0.0047 10 0 0 0 6.89E+07 1.07E+08 - - - 3.7758 0.9997 221125_WJC_METTL3_EV_vs_WT_F06.04527.04527.2 0.0135 16-Oct K.VAEIEHAEK[136.11].E "sp|P78371|TCPB_HUMAN,tr|F8VQ14|F8VQ14_HUMAN,tr|F5GWF6|F5GWF6_HUMAN" 3 1032.5331 0.54 75783 4527 2 1032.532176 517.2738 T-complex protein 1 subunit beta OS=Homo sapiens OX=9606 GN=CCT2 PE=1 SV=4 4.75 1424 - 4.43E+06 - - - -0.9191 - 2.056 0.386 - 361.5 1 2 0 -0.0009 9 0 0 0 9.47E+08 1.75E+09 - - - 3.9769 0.9998 221125_WJC_METTL3_EV_vs_WT_F06.04531.04531.2 9.49E-05 13/14 R.K[136.11]AVVVC[160.03]PK[136.11].D "sp|Q00839|HNRPU_HUMAN,tr|A0A1W2PQL0|A0A1W2PQL0_HUMAN,tr|A0A1W2PPL4|A0A1W2PPL4_HUMAN,tr|A0A1W2PQ74|A0A1W2PQ74_HUMAN,tr|Q5RI18|Q5RI18_HUMAN,tr|A0A1W2PP35|A0A1W2PP35_HUMAN,tr|A0A1W2PPS1|A0A1W2PPS1_HUMAN,tr|A0A1W2PRZ7|A0A1W2PRZ7_HUMAN,tr|A0A1W2PPH7|A0A1W2PPH7_HUMAN,tr|A0A1W2PQD4|A0A1W2PQD4_HUMAN,tr|A0A1W2PP34|A0A1W2PP34_HUMAN,tr|A0A1X7SBS1|A0A1X7SBS1_HUMAN" 12 915.5547 0.92 75785 4531 2 915.553366 458.7846 Heterogeneous nuclear ribonucleoprotein U OS=Homo sapiens OX=9606 GN=HNRNPU PE=1 SV=6 9.31 1424.5 - 2.31E+07 - - - -1.4123 - 2.492 0.416 - 696 1 2 0 -0.0013 8 0 0 0 9.00E+09 9.80E+09 - - - 4.867 0.9998 221125_WJC_METTL3_EV_vs_WT_F06.04533.04533.2 0.00432 14-Nov R.KAVVVC[160.03]PK.D "sp|Q00839|HNRPU_HUMAN,tr|A0A1W2PQL0|A0A1W2PQL0_HUMAN,tr|A0A1W2PPL4|A0A1W2PPL4_HUMAN,tr|A0A1W2PQ74|A0A1W2PQ74_HUMAN,tr|Q5RI18|Q5RI18_HUMAN,tr|A0A1W2PP35|A0A1W2PP35_HUMAN,tr|A0A1W2PPS1|A0A1W2PPS1_HUMAN,tr|A0A1W2PRZ7|A0A1W2PRZ7_HUMAN,tr|A0A1W2PPH7|A0A1W2PPH7_HUMAN,tr|A0A1W2PQD4|A0A1W2PQD4_HUMAN,tr|A0A1W2PP34|A0A1W2PP34_HUMAN,tr|A0A1X7SBS1|A0A1X7SBS1_HUMAN" 12 899.5263 0.92 75787 4533 2 899.525387 450.7704 Heterogeneous nuclear ribonucleoprotein U OS=Homo sapiens OX=9606 GN=HNRNPU PE=1 SV=6 9.31 1424.6 - 1.70E+07 - - - -0.9694 - 2.153 0.379 - 472.9 1 2 0 -0.0009 8 0 0 0 9.00E+09 9.80E+09 - - - 4.1528 0.9997 221125_WJC_METTL3_EV_vs_WT_F06.04534.04534.2 0.000871 16-Sep K.VAEIEHAEK.E "sp|P78371|TCPB_HUMAN,tr|F8VQ14|F8VQ14_HUMAN,tr|F5GWF6|F5GWF6_HUMAN" 3 1024.5189 0.54 75788 4534 2 1024.51775 513.2667 T-complex protein 1 subunit beta OS=Homo sapiens OX=9606 GN=CCT2 PE=1 SV=4 4.75 1424.6 - 3.38E+06 - - - -1.1469 - 1.847 0.431 - 280.2 1 2 0 -0.0012 9 0 0 0 9.47E+08 1.75E+09 - - - 3.9991 0.9075 221125_WJC_METTL3_EV_vs_WT_F06.04535.04535.2 0.124 16-Jul R.R[166.11]AEQDSTTV.A "sp|Q86U44|MTA70_HUMAN,tr|F5H6D8|F5H6D8_HUMAN,tr|H0YFV6|H0YFV6_HUMAN,tr|B4DTN4|B4DTN4_HUMAN" 4 1015.481 0.16 75789 4535 2 1015.480318 508.7478 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 4.37 1424.7 - 2.26E+06 - - - -0.645 - 1.408 0.263 - 167.5 1 1 0 -0.0007 9 0 0 0 3.49E+07 2.15E+08 - - - 1.9732 0.9964 221125_WJC_METTL3_EV_vs_WT_F06.04537.04537.2 0.0184 12-Jun R.QDYDAGR[166.11].G "sp|P52298|NCBP2_HUMAN,tr|C9JQX9|C9JQX9_HUMAN,tr|B3KSB0|B3KSB0_HUMAN" 3 833.3543 1.54 75791 4537 2 833.352103 417.6844 Nuclear cap-binding protein subunit 2 OS=Homo sapiens OX=9606 GN=NCBP2 PE=1 SV=1 4.21 1424.8 - 1.10E+06 - - - -2.6555 - 1.405 0.299 - 198.4 1 2 0 -0.0022 7 0 0 0 6.18E+07 4.02E+07 - - - 2.3261 0.9981 221125_WJC_METTL3_EV_vs_WT_F06.04540.04540.2 0.12 16-Jul K.IIEDQNQSK.M "sp|Q15643|TRIPB_HUMAN,tr|H0YJ97|H0YJ97_HUMAN" 2 1073.5353 1.23 75793 4540 2 1073.535177 537.7749 Thyroid receptor-interacting protein 11 OS=Homo sapiens OX=9606 GN=TRIP11 PE=1 SV=3 4.37 1425.2 - 729151 - - - -0.1174 - 1.323 0.266 - 95.8 1 2 0 -0.0001 9 0 0 0 9.20E+08 7.48E+08 - - - 1.8154 0.9997 221125_WJC_METTL3_EV_vs_WT_F06.04542.04542.2 6.65E-05 20-Nov K.IGNQAEGAGER[166.11].H "sp|P57723|PCBP4_HUMAN,tr|C9J0A4|C9J0A4_HUMAN" 2 1110.5293 0.92 75794 4542 2 1110.527354 556.2719 Poly(rC)-binding protein 4 OS=Homo sapiens OX=9606 GN=PCBP4 PE=2 SV=1 4.53 1425.5 - 998812 - - - -1.7703 - 2.394 0.41 - 438.9 1 2 0 -0.002 11 0 0 0 3.34E+07 3.63E+07 - - - 4.4302 0.9986 221125_WJC_METTL3_EV_vs_WT_F06.04544.04544.2 0.00115 16-Jul K.GHPVSTLSR.S "sp|Q8IZH2|XRN1_HUMAN,tr|H7C5E4|H7C5E4_HUMAN" 2 952.509 1.21 75796 4544 2 952.507001 477.2618 5'-3' exoribonuclease 1 OS=Homo sapiens OX=9606 GN=XRN1 PE=1 SV=1 9.76 1425.6 - 1.78E+06 - - - -2.1291 - 1.47 0.365 - 139.1 1 2 0 -0.002 9 0 0 0 1.30E+08 1.07E+08 - - - 2.8508 0.9946 221125_WJC_METTL3_EV_vs_WT_F06.04548.04548.2 0.889 12-Jul R.KIYTNVK.L sp|Q9HD45|TM9S3_HUMAN 1 864.5069 1.34 75798 4548 2 864.505433 433.2607 Transmembrane 9 superfamily member 3 OS=Homo sapiens OX=9606 GN=TM9SF3 PE=1 SV=2 9.7 1426.2 - 6.04E+06 - - - -1.7004 - 1.544 0.141 - 193.4 1 2 0 -0.0015 7 0 0 0 3.41E+08 2.55E+08 - - - 1.4583 0.9993 221125_WJC_METTL3_EV_vs_WT_F06.04549.04549.2 0.000168 20-Oct K.IGNQAEGAGER.H "sp|P57723|PCBP4_HUMAN,tr|C9J0A4|C9J0A4_HUMAN" 2 1100.5211 0.92 75799 4549 2 1100.51855 551.2678 Poly(rC)-binding protein 4 OS=Homo sapiens OX=9606 GN=PCBP4 PE=2 SV=1 4.53 1426.2 - 1.70E+06 - - - -2.2717 - 1.924 0.4 - 338.4 1 2 0 -0.0025 11 0 0 0 3.34E+07 3.63E+07 - - - 3.7649 0.9613 221125_WJC_METTL3_EV_vs_WT_F06.04568.04568.2 0.64 14-Sep R.VR[166.11]TELADK[136.11].V sp|P35579|MYH9_HUMAN 1 948.5359 1.06 75807 4568 2 948.534475 475.2752 Myosin-9 OS=Homo sapiens OX=9606 GN=MYH9 PE=1 SV=4 6.04 1428.6 - 7.31E+06 - - - -1.5181 - 1.906 0.095 - 405.6 1 2 1 -0.0014 8 0 0 0 2.10E+08 1.98E+08 - - - 1.6875 0.979 221125_WJC_METTL3_EV_vs_WT_F06.04578.04578.2 0.895 14-Jun K.STPISSSR[166.11].R "sp|Q8IZH2|XRN1_HUMAN,tr|H7C5E4|H7C5E4_HUMAN" 2 843.4326 36.84 75812 4578 2 843.431132 422.7236 5'-3' exoribonuclease 1 OS=Homo sapiens OX=9606 GN=XRN1 PE=1 SV=1 9.47 1429.7 - 9.52E+06 - - - -1.7002 - 1.095 0.16 - 159 1 2 0 -0.0014 8 0 0 0 1.36E+10 3.68E+08 - - - 0.496 0.9628 221125_WJC_METTL3_EV_vs_WT_F06.04580.04580.2 0.445 12-Jul K.IHDENLR.K "sp|O95232|LC7L3_HUMAN,tr|J3KPP4|J3KPP4_HUMAN,tr|D6RDI2|D6RDI2_HUMAN" 3 895.4512 1.84 75813 4580 2 895.449069 448.7329 Luc7-like protein 3 OS=Homo sapiens OX=9606 GN=LUC7L3 PE=1 SV=2 5.32 1429.9 - 2.19E+06 - - - -2.3564 - 1.173 0.117 - 216.1 1 2 0 -0.0021 7 0 0 0 1.13E+08 6.16E+07 - - - 0.4101 0.9995 221125_WJC_METTL3_EV_vs_WT_F06.04581.04581.2 0.000444 18-Oct K.QPQPSPAEGR.A "sp|P56192|SYMC_HUMAN,tr|H0YHV5|H0YHV5_HUMAN" 2 1065.5203 1.44 75814 4581 2 1065.522037 533.7674 "Methionine--tRNA ligase, cytoplasmic OS=Homo sapiens OX=9606 GN=MARS1 PE=1 SV=2" 6 1430 - 936617 - - - 1.6095 - 1.748 0.406 - 424.5 1 2 0 0.0017 10 0 0 0 6.40E+07 4.44E+07 - - - 3.598 0.9974 221125_WJC_METTL3_EV_vs_WT_F06.04586.04586.2 0.0367 12-Aug R.KGDYLGK.T "sp|P17812|PYRG1_HUMAN,tr|A0A3B3ITH9|A0A3B3ITH9_HUMAN,tr|A0A3B3ITF6|A0A3B3ITF6_HUMAN,tr|A0A3B3IRQ8|A0A3B3IRQ8_HUMAN,tr|A0A3B3ITB8|A0A3B3ITB8_HUMAN,tr|A0A3B3IRI2|A0A3B3IRI2_HUMAN" 6 779.4178 1.15 75816 4586 2 779.415576 390.7162 CTP synthase 1 OS=Homo sapiens OX=9606 GN=CTPS1 PE=1 SV=2 8.5 1430.6 - 6.32E+06 - - - -2.7944 - 1.485 0.327 - 240.3 1 2 0 -0.0022 7 0 0 0 2.06E+08 1.79E+08 - - - 2.7084 0.9998 221125_WJC_METTL3_EV_vs_WT_F06.04587.04587.2 0.00373 14-Aug R.SDYSEAAK.Q sp|P78527|PRKDC_HUMAN 1 869.3767 1.56 75817 4587 2 869.375294 435.6956 DNA-dependent protein kinase catalytic subunit OS=Homo sapiens OX=9606 GN=PRKDC PE=1 SV=3 4.37 1430.7 - 2.34E+06 - - - -1.5908 - 1.497 0.576 - 257.3 1 2 0 -0.0014 8 0 0 0 6.04E+07 3.86E+07 - - - 4.5117 0.9966 221125_WJC_METTL3_EV_vs_WT_F06.04611.04611.2 0.0108 14-Sep R.QVHNSFAR.Q "sp|Q9Y5K5|UCHL5_HUMAN,tr|Q5LJA9|Q5LJA9_HUMAN,tr|H0Y6Y4|H0Y6Y4_HUMAN,tr|Q5LJB0|Q5LJB0_HUMAN,tr|Q5LJA5|Q5LJA5_HUMAN" 5 957.4781 1.44 75832 4611 2 957.475053 479.7463 Ubiquitin carboxyl-terminal hydrolase isozyme L5 OS=Homo sapiens OX=9606 GN=UCHL5 PE=1 SV=3 9.76 1433.1 - 6.81E+06 - - - -3.1437 - 1.472 0.339 - 350.9 1 2 0 -0.003 8 0 0 0 3.35E+08 2.33E+08 - - - 2.7099 0.9926 221125_WJC_METTL3_EV_vs_WT_F06.04612.04612.2 0.148 14-Aug R.K[136.11]PATSYVR[166.11].T "sp|P46779|RL28_HUMAN,tr|H0YKD8|H0YKD8_HUMAN" 2 938.5304 0.92 75833 4612 2 938.528596 470.2725 60S ribosomal protein L28 OS=Homo sapiens OX=9606 GN=RPL28 PE=1 SV=3 9.99 1433.1 - 8.30E+06 - - - -1.9605 - 1.382 0.181 - 202.2 1 2 0 -0.0018 8 0 0 0 2.66E+08 2.89E+08 - - - 1.353 0.999 221125_WJC_METTL3_EV_vs_WT_F06.04617.04617.2 0.00148 16-Aug R.SMPEQTGEK[136.11].- "sp|P62888|RL30_HUMAN,tr|A0A0B4J213|A0A0B4J213_HUMAN,tr|A0A0C4DH44|A0A0C4DH44_HUMAN" 3 1013.4579 1.14 75837 4617 2 1013.456044 507.7362 60S ribosomal protein L30 OS=Homo sapiens OX=9606 GN=RPL30 PE=1 SV=2 4.53 1433.5 - 2.96E+07 - - - -1.8422 - 1.409 0.406 - 190.5 1 2 0 -0.0019 9 0 0 0 1.37E+09 1.20E+09 - - - 3.0311 0.9599 221125_WJC_METTL3_EV_vs_WT_F06.04623.04623.2 0.00749 16-Oct F.SDTGLGDGK.M "sp|Q9Y2W1|TR150_HUMAN,tr|A0A3B3ITZ9|A0A3B3ITZ9_HUMAN" 2 848.3876 2.35 75842 4623 2 848.38561 425.2011 Thyroid hormone receptor-associated protein 3 OS=Homo sapiens OX=9606 GN=THRAP3 PE=1 SV=2 4.21 1434 - 2.60E+06 - - - -2.3173 - 1.842 0.4 - 467.9 1 1 0 -0.002 9 0 0 0 5.61E+07 2.39E+07 - - - 3.762 0.9896 221125_WJC_METTL3_EV_vs_WT_F06.04625.04625.2 0.41 12-Jun R.SNQELER[166.11].L "sp|Q15643|TRIPB_HUMAN,tr|H0YJ97|H0YJ97_HUMAN" 2 884.4227 1.15 75843 4625 2 884.420544 443.2186 Thyroid receptor-interacting protein 11 OS=Homo sapiens OX=9606 GN=TRIP11 PE=1 SV=3 4.53 1434.2 - 1.70E+07 - - - -2.4705 - 1.386 0.176 - 288.7 1 2 0 -0.0022 7 0 0 0 6.42E+08 5.58E+08 - - - 1.3745 0.9783 221125_WJC_METTL3_EV_vs_WT_F06.04627.04627.2 0.474 14-Jul R.KPATSYVR.T "sp|P46779|RL28_HUMAN,tr|H0YKD8|H0YKD8_HUMAN" 2 920.508 0.92 75844 4627 2 920.505313 461.2613 60S ribosomal protein L28 OS=Homo sapiens OX=9606 GN=RPL28 PE=1 SV=3 9.99 1434.4 - 1.41E+07 - - - -2.8821 - 1.385 0.139 - 129 1 2 0 -0.0027 8 0 0 0 2.65E+08 2.89E+08 - - - 1.0491 0.9996 221125_WJC_METTL3_EV_vs_WT_F06.04637.04637.2 0.0211 12-Nov K.HYTEAIK[136.11].R sp|P31948|STIP1_HUMAN 1 868.4534 1.1 75848 4637 2 868.45129 435.234 Stress-induced-phosphoprotein 1 OS=Homo sapiens OX=9606 GN=STIP1 PE=1 SV=1 6.75 1435.7 - 4.49E+06 - - - -2.4503 - 1.972 0.453 - 508.3 1 2 0 -0.0021 7 0 0 0 1.93E+08 1.76E+08 - - - 4.5378 0.9953 221125_WJC_METTL3_EV_vs_WT_F06.04641.04641.2 0.0599 14-Sep R.QVHNSFAR[166.11].Q "sp|Q9Y5K5|UCHL5_HUMAN,tr|Q5LJA9|Q5LJA9_HUMAN,tr|H0Y6Y4|H0Y6Y4_HUMAN,tr|Q5LJB0|Q5LJB0_HUMAN,tr|Q5LJA5|Q5LJA5_HUMAN" 5 967.4863 1.44 75851 4641 2 967.484366 484.7504 Ubiquitin carboxyl-terminal hydrolase isozyme L5 OS=Homo sapiens OX=9606 GN=UCHL5 PE=1 SV=3 9.76 1436 - 7.78E+06 - - - -2.0331 - 1.449 0.213 - 353 1 2 0 -0.002 8 0 0 0 3.33E+08 2.31E+08 - - - 1.7321 0.9981 221125_WJC_METTL3_EV_vs_WT_F06.04649.04649.2 0.000558 14-Aug K.SAADDYNR.L "sp|Q9UNH7|SNX6_HUMAN,tr|A0A0A0MRI2|A0A0A0MRI2_HUMAN,tr|G3V5X9|G3V5X9_HUMAN" 3 910.3781 1.51 75854 4649 2 910.375957 456.1963 Sorting nexin-6 OS=Homo sapiens OX=9606 GN=SNX6 PE=1 SV=1 4.21 1436.9 - 4.51E+06 - - - -2.3254 - 1.45 0.343 - 247.8 1 2 0 -0.0021 8 0 0 0 8.19E+07 5.41E+07 - - - 2.6944 0.9972 221125_WJC_METTL3_EV_vs_WT_F06.04665.04665.2 6.96E-05 18-Oct R.AGVLAGHDNR[166.11].V "sp|P62879|GBB2_HUMAN,sp|Q9HAV0|GBB4_HUMAN,sp|P62873|GBB1_HUMAN,tr|B3KVK2|B3KVK2_HUMAN,tr|A0A6Q8PG88|A0A6Q8PG88_HUMAN,tr|E7EP32|E7EP32_HUMAN,tr|A0A7I2S2S9|A0A7I2S2S9_HUMAN" 7 1018.5184 1.23 75863 4665 2 1018.515046 510.2665 Guanine nucleotide-binding protein G(I)\G(S)\G(T) subunit beta-2 OS=Homo sapiens OX=9606 GN=GNB2 PE=1 SV=3 6.79 1438.8 - 2.75E+06 - - - -3.2547 - 1.837 0.306 - 411.3 1 2 0 -0.0033 10 0 0 0 7.64E+07 6.20E+07 - - - 2.9976 0.9981 221125_WJC_METTL3_EV_vs_WT_F06.04666.04666.2 0.011 12-Jun K.TQQQFTK.E "sp|Q8IWZ3|ANKH1_HUMAN,tr|E9PDP5|E9PDP5_HUMAN" 2 879.445 1.15 75864 4666 2 879.443417 440.7298 Ankyrin repeat and KH domain-containing protein 1 OS=Homo sapiens OX=9606 GN=ANKHD1 PE=1 SV=1 8.41 1438.8 - 1.82E+07 - - - -1.8352 - 1.276 0.35 - 191.8 1 2 0 -0.0016 7 0 0 0 3.92E+08 3.42E+08 - - - 2.3979 0.9994 221125_WJC_METTL3_EV_vs_WT_F06.04670.04670.2 0.00344 14-Aug R.QSAC[160.03]NLEK.K sp|P35579|MYH9_HUMAN 1 948.4335 0.95 75867 4670 2 948.431729 475.224 Myosin-9 OS=Homo sapiens OX=9606 GN=MYH9 PE=1 SV=4 5.99 1439.3 - 2.36E+07 - - - -1.8473 - 1.629 0.418 - 296.5 1 2 0 -0.0018 8 0 0 0 4.88E+08 5.12E+08 - - - 3.5995 0.9978 221125_WJC_METTL3_EV_vs_WT_F06.04672.04672.2 0.00185 20-Oct K.ADGTATAPPPR[166.11].S sp|Q7Z6Z7|HUWE1_HUMAN 1 1062.5333 1.21 75868 4672 2 1062.53127 532.2739 E3 ubiquitin-protein ligase HUWE1 OS=Homo sapiens OX=9606 GN=HUWE1 PE=1 SV=3 5.88 1439.5 - 801774 - - - -1.951 - 1.958 0.197 - 280.3 1 2 0 -0.0021 11 0 0 0 2.72E+07 2.24E+07 - - - 2.3131 0.9879 221125_WJC_METTL3_EV_vs_WT_F06.04677.04677.2 0.681 12-Jun K.HYTEAIK.R sp|P31948|STIP1_HUMAN 1 860.4392 1.03 75871 4677 2 860.438051 431.2269 Stress-induced-phosphoprotein 1 OS=Homo sapiens OX=9606 GN=STIP1 PE=1 SV=1 6.75 1440.1 - 7.90E+06 - - - -1.3563 - 1.085 0.194 - 176 1 2 0 -0.0012 7 0 0 0 1.91E+08 1.85E+08 - - - 0.732 0.9915 221125_WJC_METTL3_EV_vs_WT_F06.04681.04681.2 0.508 14-Jul R.RFSADAAR.F "sp|Q9Y2R4|DDX52_HUMAN,tr|A0A087X069|A0A087X069_HUMAN,tr|A0A087WTD6|A0A087WTD6_HUMAN,tr|A0A087X1P7|A0A087X1P7_HUMAN" 4 892.4515 0.5 75875 4681 2 892.452357 447.233 Probable ATP-dependent RNA helicase DDX52 OS=Homo sapiens OX=9606 GN=DDX52 PE=1 SV=3 9.6 1440.6 - 1.34E+06 - - - 0.9446 - 1.265 0.156 - 114 1 2 0 0.0008 8 0 0 0 2.00E+07 3.99E+07 - - - 0.9019 0.9985 221125_WJC_METTL3_EV_vs_WT_F06.04682.04682.2 0.00903 14-Oct R.LLDQHDQR.G "sp|P29084|T2EB_HUMAN,tr|E5RH41|E5RH41_HUMAN" 2 1023.5098 0.56 75876 4682 2 1023.507711 512.7622 Transcription initiation factor IIE subunit beta OS=Homo sapiens OX=9606 GN=GTF2E2 PE=1 SV=1 5.21 1440.7 - 1.12E+06 - - - -1.999 - 1.679 0.288 - 391 1 2 0 -0.002 8 0 0 0 1.84E+07 3.30E+07 - - - 2.7304 0.9908 221125_WJC_METTL3_EV_vs_WT_F06.04687.04687.2 0.053 14-Jun K.YLPHSAGR.Y "sp|P46782|RS5_HUMAN,tr|M0R0F0|M0R0F0_HUMAN,tr|M0R0R2|M0R0R2_HUMAN" 3 899.4614 0.7 75879 4687 2 899.45934 450.738 40S ribosomal protein S5 OS=Homo sapiens OX=9606 GN=RPS5 PE=1 SV=4 8.75 1441.2 - 5.66E+06 - - - -2.2347 - 1.071 0.283 - 155.8 1 2 0 -0.002 8 0 0 0 2.48E+08 3.57E+08 - - - 1.3375 0.9879 221125_WJC_METTL3_EV_vs_WT_F06.04689.04689.2 0.727 12-May K.SNNLTDR.L "sp|Q86X55|CARM1_HUMAN,tr|K7EQA8|K7EQA8_HUMAN" 2 818.3882 0.42 75881 4689 2 818.389578 410.2014 Histone-arginine methyltransferase CARM1 OS=Homo sapiens OX=9606 GN=CARM1 PE=1 SV=3 5.55 1441.3 - 5.19E+06 - - - 1.6288 - 1.171 0.185 - 124 1 2 0 0.0013 7 0 0 0 3.29E+07 7.85E+07 - - - 0.9072 0.9998 221125_WJC_METTL3_EV_vs_WT_F06.04693.04693.2 0.000567 13/20 R.IAATTGNGQPR.R tr|Q9UG54|Q9UG54_HUMAN 1 1084.5625 0.9 75884 4693 2 1084.562692 543.2885 Mitogen-activated protein kinase kinase kinase OS=Homo sapiens OX=9606 GN=MAP3K7 PE=1 SV=1 9.75 1441.6 - 1.19E+06 - - - 0.1577 - 2.092 0.379 - 518 1 2 0 0.0002 11 0 0 0 2.13E+07 2.35E+07 - - - 3.837 0.9996 221125_WJC_METTL3_EV_vs_WT_F06.04694.04694.2 0.0118 18-Oct R.LAQEEESEAK[136.11].R "sp|O00541|PESC_HUMAN,tr|B3KXD6|B3KXD6_HUMAN,tr|B5MCF9|B5MCF9_HUMAN,tr|H7C267|H7C267_HUMAN" 4 1140.539 0.56 75885 4694 2 1140.538611 571.2768 Pescadillo homolog OS=Homo sapiens OX=9606 GN=PES1 PE=1 SV=1 4.09 1441.8 - 1.12E+06 - - - -0.3393 - 2.25 0.284 - 341.5 1 2 0 -0.0004 10 0 0 0 1.57E+07 2.78E+07 - - - 3.4021 0.9877 221125_WJC_METTL3_EV_vs_WT_F06.04696.04696.2 0.183 12-Apr K.TQQQFTK[136.11].E "sp|Q8IWZ3|ANKH1_HUMAN,tr|E9PDP5|E9PDP5_HUMAN" 2 887.4592 1.14 75886 4696 2 887.457793 444.7369 Ankyrin repeat and KH domain-containing protein 1 OS=Homo sapiens OX=9606 GN=ANKHD1 PE=1 SV=1 8.41 1442 - 1.49E+07 - - - -1.6204 - 1.157 0.179 - 84.9 1 2 0 -0.0014 7 0 0 0 3.91E+08 3.42E+08 - - - 0.8247 0.9995 221125_WJC_METTL3_EV_vs_WT_F06.04699.04699.2 0.0967 14-Jul K.IQNDAGVR.L "sp|Q96I24|FUBP3_HUMAN,sp|Q92945|FUBP2_HUMAN,sp|Q96AE4|FUBP1_HUMAN,tr|M0R0I5|M0R0I5_HUMAN,tr|E9PEB5|E9PEB5_HUMAN,tr|M0R0C6|M0R0C6_HUMAN,tr|A0A087WTP3|A0A087WTP3_HUMAN" 7 871.4512 4 75888 4699 2 871.451065 436.7329 Far upstream element-binding protein 3 OS=Homo sapiens OX=9606 GN=FUBP3 PE=1 SV=2 5.84 1442.2 - 3.56E+06 - - - -0.1308 - 1.725 0.314 - 156.2 1 2 0 -0.0001 8 0 0 0 1.62E+08 4.06E+07 - - - 3.0045 0.9998 221125_WJC_METTL3_EV_vs_WT_F06.04701.04701.2 4.61E-05 16-Aug R.LSEC[160.03]EEQAK[136.11].A sp|Q7KZF4|SND1_HUMAN 1 1100.4899 1.43 75890 4701 2 1100.490628 551.2522 Staphylococcal nuclease domain-containing protein 1 OS=Homo sapiens OX=9606 GN=SND1 PE=1 SV=1 4.25 1442.3 - 3.85E+06 - - - 0.6261 - 1.739 0.451 - 190 1 2 0 0.0007 9 0 0 0 3.21E+07 2.25E+07 - - - 3.9726 0.9741 221125_WJC_METTL3_EV_vs_WT_F06.04702.04702.2 1.93 14-Jul K.VKPQLEEK.T "sp|P01040|CYTA_HUMAN,tr|C9J0E4|C9J0E4_HUMAN" 2 969.5495 999 75891 4702 2 969.549474 485.782 Cystatin-A OS=Homo sapiens OX=9606 GN=CSTA PE=1 SV=1 6.11 1442.4 - 3.42E+06 - - - -0.0227 - 1.193 0.085 - 104.4 3 2 0 0 8 0 0 0 3.53E+08 0.00E+00 - - - -0.0121 0.9762 221125_WJC_METTL3_EV_vs_WT_F06.04703.04703.2 0.000652 16-Aug E.EANQAINPK[136.11].L "sp|Q92841|DDX17_HUMAN,sp|P17844|DDX5_HUMAN,tr|A0A5H1ZRQ2|A0A5H1ZRQ2_HUMAN,tr|J3KTA4|J3KTA4_HUMAN,tr|A0A0G2JLI4|A0A0G2JLI4_HUMAN,tr|A0A1X7SBZ2|A0A1X7SBZ2_HUMAN" 6 991.5178 -1 75892 4703 2 991.517697 496.7662 Probable ATP-dependent RNA helicase DDX17 OS=Homo sapiens OX=9606 GN=DDX17 PE=1 SV=2 6.1 1442.5 - 2.34E+06 - - - -0.113 - 1.616 0.379 - 275.5 1 1 0 -0.0001 9 0 0 0 0.00E+00 0.00E+00 - - - 3.2288 0.9998 221125_WJC_METTL3_EV_vs_WT_F06.04707.04707.2 0.00156 18-Nov R.LAQEEESEAK.R "sp|O00541|PESC_HUMAN,tr|B3KXD6|B3KXD6_HUMAN,tr|B5MCF9|B5MCF9_HUMAN,tr|H7C267|H7C267_HUMAN" 4 1132.5248 0.45 75895 4707 2 1132.525122 567.2697 Pescadillo homolog OS=Homo sapiens OX=9606 GN=PES1 PE=1 SV=1 4.09 1442.9 - 1.07E+06 - - - 0.2861 - 2.13 0.415 - 486.9 1 2 0 0.0003 10 0 0 0 1.17E+07 2.59E+07 - - - 4.2167 0.8873 221125_WJC_METTL3_EV_vs_WT_F06.04714.04714.2 0.00636 14-Jun A.PGFGDNRK.N "sp|P10809|CH60_HUMAN,tr|A0A7I2V2X6|A0A7I2V2X6_HUMAN,tr|A0A7I2YQK6|A0A7I2YQK6_HUMAN,tr|A0A7I2V599|A0A7I2V599_HUMAN,tr|A0A7I2V5M1|A0A7I2V5M1_HUMAN" 5 889.4406 1.1 75900 4714 2 889.439436 445.7276 "60 kDa heat shock protein, mitochondrial OS=Homo sapiens OX=9606 GN=HSPD1 PE=1 SV=2" 9.18 1443.5 - 1.05E+07 - - - -1.3256 - 1.415 0.262 - 98.3 1 1 0 -0.0012 8 0 0 0 8.96E+08 8.15E+08 - - - 2.0227 0.9962 221125_WJC_METTL3_EV_vs_WT_F06.04717.04717.2 0.0704 12-Aug K.SNNLTDR[166.11].L "sp|Q86X55|CARM1_HUMAN,tr|K7EQA8|K7EQA8_HUMAN" 2 828.3965 0.82 75903 4717 2 828.394744 415.2055 Histone-arginine methyltransferase CARM1 OS=Homo sapiens OX=9606 GN=CARM1 PE=1 SV=3 5.55 1443.7 - 3.16E+06 - - - -2.1379 - 1.507 0.222 - 263.7 1 2 0 -0.0018 7 0 0 0 4.39E+07 5.34E+07 - - - 1.9796 0.9917 221125_WJC_METTL3_EV_vs_WT_F06.04719.04719.2 0.00233 14-Sep K.SHEAEVLK[136.11].Q "sp|P16949|STMN1_HUMAN,tr|A2A2D0|A2A2D0_HUMAN" 2 919.4854 3.64 75904 4719 2 919.480164 460.75 Stathmin OS=Homo sapiens OX=9606 GN=STMN1 PE=1 SV=3 5.38 1443.8 - 2.04E+06 - - - -5.7445 - 1.895 0.379 - 320.4 1 2 0 -0.0053 8 0 0 0 7.84E+07 2.15E+07 - - - 3.7665 0.9985 221125_WJC_METTL3_EV_vs_WT_F06.04726.04726.2 0.0112 12-Jun R.NYADHVR[166.11].E sp|Q6P587|FAHD1_HUMAN 1 883.4176 1.82 75909 4726 2 883.417825 442.7161 "Acylpyruvase FAHD1, mitochondrial OS=Homo sapiens OX=9606 GN=FAHD1 PE=1 SV=2" 6.74 1444.6 - 4.55E+06 - - - 0.2728 - 1.165 0.341 - 218 1 2 0 0.0002 7 0 0 0 1.58E+09 8.66E+08 - - - 2.0435 0.9844 221125_WJC_METTL3_EV_vs_WT_F06.04727.04727.2 0.253 14-Aug R.SQQELEAK[136.11].L sp|Q14008|CKAP5_HUMAN 1 939.4753 1.1 75910 4727 2 939.477368 470.7449 Cytoskeleton-associated protein 5 OS=Homo sapiens OX=9606 GN=CKAP5 PE=1 SV=3 4.53 1444.7 - 2.49E+06 - - - 2.2278 - 1.614 0.068 - 307 1 2 0 0.0021 8 0 0 0 9.61E+07 8.71E+07 - - - 0.9864 0.9934 221125_WJC_METTL3_EV_vs_WT_F06.04728.04728.2 2.43 14-Sep R.KAEAVALK.Y "sp|O00461|GOLI4_HUMAN,tr|F8W785|F8W785_HUMAN" 2 828.5069 1.78 75911 4728 2 828.505819 415.2607 Golgi integral membrane protein 4 OS=Homo sapiens OX=9606 GN=GOLIM4 PE=1 SV=1 8.59 1444.7 - 1.93E+06 - - - -1.3084 - 1.524 0.112 - 239.6 1 2 0 -0.0011 8 0 0 0 4.66E+07 2.61E+07 - - - 1.1386 0.9979 221125_WJC_METTL3_EV_vs_WT_F06.04733.04733.2 0.00935 16-Jul K.APGFGDNR[166.11]K[136.11].N "sp|P10809|CH60_HUMAN,tr|A0A7I2V2X6|A0A7I2V2X6_HUMAN,tr|A0A7I2YQK6|A0A7I2YQK6_HUMAN,tr|A0A7I2V599|A0A7I2V599_HUMAN,tr|A0A7I2V5M1|A0A7I2V5M1_HUMAN" 5 978.5002 1.27 75914 4733 2 978.499214 490.2574 "60 kDa heat shock protein, mitochondrial OS=Homo sapiens OX=9606 GN=HSPD1 PE=1 SV=2" 8.79 1445.4 - 3.08E+07 - - - -1.0056 - 1.326 0.279 - 176.3 1 2 0 -0.001 9 0 0 0 1.17E+09 9.23E+08 - - - 1.9177 0.9968 221125_WJC_METTL3_EV_vs_WT_F06.04736.04736.2 0.0185 12-Jul R.HTLAYDK.G "sp|Q6P2Q9|PRP8_HUMAN,tr|I3L3Z8|I3L3Z8_HUMAN" 2 846.4236 0.86 75917 4736 2 846.422166 424.2191 Pre-mRNA-processing-splicing factor 8 OS=Homo sapiens OX=9606 GN=PRPF8 PE=1 SV=2 6.74 1445.5 - 3.77E+06 - - - -1.6564 - 1.383 0.239 - 156.8 1 2 0 -0.0014 7 0 0 0 3.82E+08 4.46E+08 - - - 1.8332 0.9991 221125_WJC_METTL3_EV_vs_WT_F06.04737.04737.2 1.91 16-Nov K.TLQQNAESR[166.11].F sp|O95816|BAG2_HUMAN 1 1055.5235 0.23 75918 4737 2 1055.522218 528.769 BAG family molecular chaperone regulator 2 OS=Homo sapiens OX=9606 GN=BAG2 PE=1 SV=1 5.66 1445.6 - 3.33E+06 - - - -1.2202 - 1.782 0.274 - 401.2 1 2 0 -0.0013 9 0 0 0 2.55E+08 1.12E+09 - - - 2.7358 0.9913 221125_WJC_METTL3_EV_vs_WT_F06.04738.04738.2 0.228 14-Jul R.SQQELEAK.L sp|Q14008|CKAP5_HUMAN 1 931.4611 1.01 75919 4738 2 931.462682 466.7378 Cytoskeleton-associated protein 5 OS=Homo sapiens OX=9606 GN=CKAP5 PE=1 SV=3 4.53 1445.6 - 3.04E+06 - - - 1.7252 - 1.53 0.117 - 229.8 1 2 0 0.0016 8 0 0 0 8.40E+07 8.31E+07 - - - 1.1872 0.991 221125_WJC_METTL3_EV_vs_WT_F06.04743.04743.2 0.98 16-Aug K.LQQAPNQPK.L "sp|Q7Z589|EMSY_HUMAN,tr|H0YET8|H0YET8_HUMAN,tr|E9PMC9|E9PMC9_HUMAN" 3 1022.5509 1.01 75922 4743 2 1022.548947 512.2827 BRCA2-interacting transcriptional repressor EMSY OS=Homo sapiens OX=9606 GN=EMSY PE=1 SV=2 8.75 1446.1 - 1.81E+06 - - - -1.9031 - 1.465 0.14 - 185 1 2 0 -0.0019 9 0 0 0 5.00E+07 4.95E+07 - - - 1.1792 0.9988 221125_WJC_METTL3_EV_vs_WT_F06.04744.04744.2 0.0399 16-Aug K.LQQAPNQPK[136.11].L "sp|Q7Z589|EMSY_HUMAN,tr|H0YET8|H0YET8_HUMAN,tr|E9PMC9|E9PMC9_HUMAN" 3 1030.5651 1.02 75923 4744 2 1030.56384 516.2898 BRCA2-interacting transcriptional repressor EMSY OS=Homo sapiens OX=9606 GN=EMSY PE=1 SV=2 8.75 1446.2 - 1.66E+06 - - - -1.2158 - 1.703 0.255 - 199.4 1 2 0 -0.0013 9 0 0 0 5.06E+07 4.95E+07 - - - 2.4643 0.9894 221125_WJC_METTL3_EV_vs_WT_F06.04747.04747.2 0.169 16-Sep R.QIQEEEDEK.Q "sp|O43805|SSNA1_HUMAN,tr|A0A087WV26|A0A087WV26_HUMAN" 2 1146.5041 2.86 75926 4747 2 1146.506623 574.2593 Sjoegren syndrome nuclear autoantigen 1 OS=Homo sapiens OX=9606 GN=SSNA1 PE=1 SV=2 3.91 1446.5 - 417167 - - - 2.2337 - 1.596 0.119 - 225.3 1 2 0 0.0026 9 0 0 0 2.98E+07 1.04E+07 - - - 1.2716 0.9973 221125_WJC_METTL3_EV_vs_WT_F06.04748.04748.2 0.00139 16-Aug R.QIQEEEDEK[136.11].Q "sp|O43805|SSNA1_HUMAN,tr|A0A087WV26|A0A087WV26_HUMAN" 2 1154.5183 2.86 75927 4748 2 1154.515935 578.2664 Sjoegren syndrome nuclear autoantigen 1 OS=Homo sapiens OX=9606 GN=SSNA1 PE=1 SV=2 3.91 1446.7 - 224192 - - - -2.0156 - 1.697 0.218 - 144.2 1 2 0 -0.0023 9 0 0 0 2.98E+07 1.04E+07 - - - 2.1804 0.9977 221125_WJC_METTL3_EV_vs_WT_F06.04751.04751.2 0.0447 14-Aug R.SVSSSSYR[166.11].R "sp|P08670|VIME_HUMAN,tr|B0YJC4|B0YJC4_HUMAN,tr|A0A1B0GVG8|A0A1B0GVG8_HUMAN,tr|A0A1B0GTT5|A0A1B0GTT5_HUMAN" 4 881.4118 1.72 75928 4751 2 881.411521 441.7132 Vimentin OS=Homo sapiens OX=9606 GN=VIM PE=1 SV=4 8.46 1447.1 - 1.64E+07 - - - -0.3506 - 1.359 0.231 - 161.9 1 2 0 -0.0003 8 0 0 0 1.32E+10 7.70E+09 - - - 1.6722 0.9892 221125_WJC_METTL3_EV_vs_WT_F06.04752.04752.2 0.303 12-Jun K.KLEEVER.K "sp|Q14152|EIF3A_HUMAN,sp|Q96Q89|KI20B_HUMAN" 2 901.4869 1.67 75929 4752 2 901.487631 451.7507 Eukaryotic translation initiation factor 3 subunit A OS=Homo sapiens OX=9606 GN=EIF3A PE=1 SV=1 4.79 1447.1 - 6.83E+06 - - - 0.8153 - 1.319 0.106 - 168.6 1 2 0 0.0007 7 0 0 0 1.57E+08 9.43E+07 - - - 0.701 0.9983 221125_WJC_METTL3_EV_vs_WT_F06.04753.04753.2 0.564 14-Aug R.SVSSSSYR.R "sp|P08670|VIME_HUMAN,tr|B0YJC4|B0YJC4_HUMAN,tr|A0A1B0GVG8|A0A1B0GVG8_HUMAN,tr|A0A1B0GTT5|A0A1B0GTT5_HUMAN" 4 871.4036 1.72 75930 4753 2 871.403154 436.7091 Vimentin OS=Homo sapiens OX=9606 GN=VIM PE=1 SV=4 8.46 1447.1 - 1.84E+07 - - - -0.4659 - 1.428 0.246 - 165.9 1 2 0 -0.0004 8 0 0 0 1.32E+10 7.70E+09 - - - 1.9323 0.9626 221125_WJC_METTL3_EV_vs_WT_F06.04756.04756.2 2.7 18-May K.LTQDMSQDEK[136.11].V sp|Q8IY84|NIM1_HUMAN 1 1201.5376 0.69 75933 4756 2 1201.537658 601.7761 Serine\threonine-protein kinase NIM1 OS=Homo sapiens OX=9606 GN=NIM1K PE=1 SV=1 4.03 1447.4 - 568221 - - - 0.0333 - 1.039 0.1 - 82.5 2 2 0 0 10 0 0 0 6.74E+06 9.78E+06 - - - -0.2481 0.9988 221125_WJC_METTL3_EV_vs_WT_F06.04760.04760.2 0.449 20-Jul R.GPPPAPEGGSR.D "sp|P46379|BAG6_HUMAN,tr|A0A7I2V508|A0A7I2V508_HUMAN,tr|H0Y710|H0Y710_HUMAN,tr|A0A7P0MQS5|A0A7P0MQS5_HUMAN,tr|A0A0G2JL47|A0A0G2JL47_HUMAN,tr|A0A024RCR6|A0A024RCR6_HUMAN,tr|A0A0G2JK23|A0A0G2JK23_HUMAN" 7 1020.4989 1.21 75935 4760 2 1020.498976 511.2567 Large proline-rich protein BAG6 OS=Homo sapiens OX=9606 GN=BAG6 PE=1 SV=2 6 1447.9 - 1.81E+06 - - - 0.1156 - 1.685 0.235 - 156.5 1 2 0 0.0001 11 0 0 0 6.70E+07 5.56E+07 - - - 2.1882 0.8119 221125_WJC_METTL3_EV_vs_WT_F06.04767.04767.2 0.0646 22-Jul S.GAPSAGPEPAPR[166.11].L sp|O60240|PLIN1_HUMAN 1 1115.5599 0.001 75939 4767 2 1115.557706 558.7872 Perilipin-1 OS=Homo sapiens OX=9606 GN=PLIN1 PE=1 SV=2 6 1448.7 - 978302 - - - -1.9596 - 1.317 0.302 - 81.6 2 1 0 -0.0022 12 0 0 0 0.00E+00 1.29E+07 - - - 1.8609 0.9987 221125_WJC_METTL3_EV_vs_WT_F06.04769.04769.2 0.0209 14-Jul K.DNNLTTGK.L "sp|P17812|PYRG1_HUMAN,sp|Q9NRF8|PYRG2_HUMAN,tr|A0A3B3ITH9|A0A3B3ITH9_HUMAN,tr|A0A3B3ITF6|A0A3B3ITF6_HUMAN,tr|A0A3B3IRQ8|A0A3B3IRQ8_HUMAN,tr|A0A3B3ITB8|A0A3B3ITB8_HUMAN,tr|A0A3B3IRI2|A0A3B3IRI2_HUMAN" 7 861.4192 0.82 75940 4769 2 861.418524 431.7169 CTP synthase 1 OS=Homo sapiens OX=9606 GN=CTPS1 PE=1 SV=2 5.84 1448.9 - 2.48E+06 - - - -0.7975 - 1.39 0.297 - 265.9 1 2 0 -0.0007 8 0 0 0 1.45E+08 1.77E+08 - - - 2.2276 0.9765 221125_WJC_METTL3_EV_vs_WT_F06.04775.04775.2 4.07 12-Jul K.SILGNKK.F "sp|P52740|ZN132_HUMAN,tr|A0A1W2PPT3|A0A1W2PPT3_HUMAN" 2 758.465 0.84 75945 4775 2 758.46417 380.2398 Zinc finger protein 132 OS=Homo sapiens OX=9606 GN=ZNF132 PE=2 SV=2 10 1449.6 - 2.14E+06 - - - -1.1444 - 1.203 0.079 - 175.6 1 2 0 -0.0009 7 0 0 0 4.38E+07 5.24E+07 - - - 0.2098 0.9998 221125_WJC_METTL3_EV_vs_WT_F06.04780.04780.2 4.72E-05 22-Dec R.SAGGEPGPEAGR[166.11].A "sp|O95785|WIZ_HUMAN,tr|A0A669KBG4|A0A669KBG4_HUMAN,tr|A0A2R8YFV2|A0A2R8YFV2_HUMAN,tr|A0A669KAV7|A0A669KAV7_HUMAN,tr|M0QXA7|M0QXA7_HUMAN,tr|A0A669KBH9|A0A669KBH9_HUMAN,tr|B9EGQ5|B9EGQ5_HUMAN" 7 1093.5028 1.53 75948 4780 2 1093.502161 547.7587 Protein Wiz OS=Homo sapiens OX=9606 GN=WIZ PE=1 SV=2 4.53 1450.1 - 1.39E+06 - - - -0.5578 - 2.124 0.458 - 387.7 1 2 0 -0.0006 12 0 0 0 1.33E+08 8.70E+07 - - - 4.4057 0.9969 221125_WJC_METTL3_EV_vs_WT_F06.04785.04785.2 0.0188 14-Sep K.TPTSQSYR[166.11].- sp|Q9Y2X9|ZN281_HUMAN 1 948.454 1.42 75951 4785 2 948.451831 475.2343 Zinc finger protein 281 OS=Homo sapiens OX=9606 GN=ZNF281 PE=1 SV=1 8.41 1450.7 - 1.65E+06 - - - -2.3185 - 1.616 0.239 - 263.8 1 2 0 -0.0022 8 0 0 0 8.08E+07 5.68E+07 - - - 2.2531 0.9393 221125_WJC_METTL3_EV_vs_WT_F06.04786.04786.2 0.0731 12-Jul S.VSSSSYR.R "sp|P08670|VIME_HUMAN,tr|B0YJC4|B0YJC4_HUMAN,tr|A0A1B0GVG8|A0A1B0GVG8_HUMAN,tr|A0A1B0GTT5|A0A1B0GTT5_HUMAN" 4 784.3715 0.93 75952 4786 2 784.37174 393.193 Vimentin OS=Homo sapiens OX=9606 GN=VIM PE=1 SV=4 8.72 1450.8 - 1.01E+06 - - - 0.2652 - 1.385 0.306 - 142 1 1 0 0.0002 7 0 0 0 2.21E+07 2.37E+07 - - - 2.333 0.9998 221125_WJC_METTL3_EV_vs_WT_F06.04792.04792.2 0.0156 18-Oct K.GTTGTQLNGR[166.11].Q "sp|Q9BX40|LS14B_HUMAN,tr|Q5TBP9|Q5TBP9_HUMAN,tr|Q5TBQ1|Q5TBQ1_HUMAN,tr|Q5TBQ0|Q5TBQ0_HUMAN" 4 1013.5129 0.87 75956 4792 2 1013.511757 507.7637 Protein LSM14 homolog B OS=Homo sapiens OX=9606 GN=LSM14B PE=1 SV=1 9.75 1451.4 - 4.85E+06 - - - -1.1682 - 2.292 0.447 - 621.6 1 2 0 -0.0012 10 0 0 0 1.90E+08 2.19E+08 - - - 4.6573 0.9881 221125_WJC_METTL3_EV_vs_WT_F06.04796.04796.2 0.122 14-Jun R.QQQQEALR.R "sp|Q6Y7W6|GGYF2_HUMAN,tr|A0A7I2V3H7|A0A7I2V3H7_HUMAN,tr|I1E4Y6|I1E4Y6_HUMAN,tr|A0A7I2V516|A0A7I2V516_HUMAN,tr|A0A7I2V3H0|A0A7I2V3H0_HUMAN,tr|A0A7I2V361|A0A7I2V361_HUMAN" 6 999.5098 2.92 75958 4796 2 999.506278 500.7622 GRB10-interacting GYF protein 2 OS=Homo sapiens OX=9606 GN=GIGYF2 PE=1 SV=1 6 1451.9 - 7.85E+06 - - - -3.4807 - 1.428 0.233 - 190.2 1 2 0 -0.0035 8 0 0 0 5.51E+08 1.89E+08 - - - 1.8354 0.9552 221125_WJC_METTL3_EV_vs_WT_F06.04798.04798.2 1.61 14-Jun K.TPTSQSYR.- sp|Q9Y2X9|ZN281_HUMAN 1 938.4458 1.36 75960 4798 2 938.444005 470.2302 Zinc finger protein 281 OS=Homo sapiens OX=9606 GN=ZNF281 PE=1 SV=1 8.41 1452 - 3.08E+06 - - - -1.8701 - 1.247 0.048 - 149.8 1 2 0 -0.0018 8 0 0 0 7.72E+07 5.68E+07 - - - 0.0607 0.9998 221125_WJC_METTL3_EV_vs_WT_F06.04802.04802.2 0.0032 18-Sep K.GTTGTQLNGR.Q "sp|Q9BX40|LS14B_HUMAN,tr|Q5TBP9|Q5TBP9_HUMAN,tr|Q5TBQ1|Q5TBQ1_HUMAN,tr|Q5TBQ0|Q5TBQ0_HUMAN" 4 1003.5047 0.87 75961 4802 2 1003.503775 502.7596 Protein LSM14 homolog B OS=Homo sapiens OX=9606 GN=LSM14B PE=1 SV=1 9.75 1452.6 - 6.59E+06 - - - -0.8929 - 2.082 0.446 - 502.2 1 2 0 -0.0009 10 0 0 0 1.90E+08 2.19E+08 - - - 4.3818 0.9916 221125_WJC_METTL3_EV_vs_WT_F06.04804.04804.2 0.0066 16-Aug K.GATPAPPGK.A "sp|Q13428|TCOF_HUMAN,tr|E7ETY2|E7ETY2_HUMAN,tr|H0Y8Y7|H0Y8Y7_HUMAN,tr|A0A3B3IS06|A0A3B3IS06_HUMAN,tr|A0A6I8PRA0|A0A6I8PRA0_HUMAN" 5 794.4287 1.03 75963 4804 2 794.427265 398.2216 Treacle protein OS=Homo sapiens OX=9606 GN=TCOF1 PE=1 SV=3 8.75 1452.7 - 5.02E+06 - - - -1.7472 - 1.598 0.103 - 243.1 1 2 0 -0.0014 9 0 0 0 2.46E+08 2.40E+08 - - - 1.1574 0.999 221125_WJC_METTL3_EV_vs_WT_F06.04809.04809.2 0.0502 16-Jul R.SYTSGPGSR.L "sp|P05787|K2C8_HUMAN,tr|F8VUG2|F8VUG2_HUMAN,tr|F8W1U3|F8W1U3_HUMAN,tr|F8VQY3|F8VQY3_HUMAN" 4 910.4145 0.98 75966 4809 2 910.412924 456.2145 "Keratin, type II cytoskeletal 8 OS=Homo sapiens OX=9606 GN=KRT8 PE=1 SV=7" 8.46 1453.3 - 4.86E+06 - - - -1.686 - 1.293 0.418 - 154 1 2 0 -0.0015 9 0 0 0 3.11E+08 3.17E+08 - - - 2.8713 0.9195 221125_WJC_METTL3_EV_vs_WT_F06.04810.04810.2 1.58 14-Jun R.GSEPVPEK.K "sp|Q8WU79|SMAP2_HUMAN,tr|A0A087WV97|A0A087WV97_HUMAN,tr|X6RCC3|X6RCC3_HUMAN" 3 841.4181 1.67 75967 4810 2 841.415482 421.7164 Stromal membrane-associated protein 2 OS=Homo sapiens OX=9606 GN=SMAP2 PE=1 SV=1 4.53 1453.4 - 4.08E+06 - - - -3.1685 - 1.226 0.101 - 154.7 2 2 0 -0.0027 8 0 0 0 1.40E+08 8.39E+07 - - - 0.2662 0.9979 221125_WJC_METTL3_EV_vs_WT_F06.04819.04819.2 0.0149 12-Jul K.TQQSFEK.Q "sp|Q14157|UBP2L_HUMAN,tr|F8W726|F8W726_HUMAN,tr|H7C2T8|H7C2T8_HUMAN,tr|H0Y5H6|H0Y5H6_HUMAN" 4 866.4134 2.4 75973 4819 2 866.41348 434.214 Ubiquitin-associated protein 2-like OS=Homo sapiens OX=9606 GN=UBAP2L PE=1 SV=2 5.66 1454.3 - 8.30E+06 - - - 0.0958 - 1.327 0.247 - 243.6 1 2 0 0.0001 7 0 0 0 1.83E+09 7.64E+08 - - - 1.7618 0.9989 221125_WJC_METTL3_EV_vs_WT_F06.04825.04825.2 0.12 12-Aug K.RYESQLR.D sp|O15212|PFD6_HUMAN 1 950.4934 2.81 75976 4825 2 950.492508 476.254 Prefoldin subunit 6 OS=Homo sapiens OX=9606 GN=PFDN6 PE=1 SV=1 8.75 1455.1 - 3.54E+06 - - - -0.9153 - 1.47 0.292 - 166.1 1 2 0 -0.0009 7 0 0 0 2.36E+08 8.41E+07 - - - 2.4182 0.9125 221125_WJC_METTL3_EV_vs_WT_F06.04826.04826.2 0.0613 12-Aug R.SKVDDLR.G sp|P62191|PRS4_HUMAN 1 831.445 1.4 75977 4826 2 831.444532 416.7298 26S proteasome regulatory subunit 4 OS=Homo sapiens OX=9606 GN=PSMC1 PE=1 SV=1 5.68 1455.2 - 2.07E+06 - - - -0.6002 - 1.474 0.067 - 268.9 1 2 1 -0.0005 7 0 0 0 8.58E+07 6.13E+07 - - - 0.765 0.9975 221125_WJC_METTL3_EV_vs_WT_F06.04827.04827.2 1.03 14-Aug R.QQQQEALR[166.11].R "sp|Q6Y7W6|GGYF2_HUMAN,tr|A0A7I2V3H7|A0A7I2V3H7_HUMAN,tr|I1E4Y6|I1E4Y6_HUMAN,tr|A0A7I2V516|A0A7I2V516_HUMAN,tr|A0A7I2V3H0|A0A7I2V3H0_HUMAN,tr|A0A7I2V361|A0A7I2V361_HUMAN" 6 1009.518 2.82 75978 4827 2 1009.51653 505.7663 GRB10-interacting GYF protein 2 OS=Homo sapiens OX=9606 GN=GIGYF2 PE=1 SV=1 6 1455.2 - 1.09E+07 - - - -1.4829 - 1.585 0.206 - 395.6 1 2 0 -0.0015 8 0 0 0 5.33E+08 1.89E+08 - - - 1.9511 0.9999 221125_WJC_METTL3_EV_vs_WT_F06.04828.04828.2 0.000245 22-Dec R.SAGGEPGPEAGR.A "sp|O95785|WIZ_HUMAN,tr|A0A669KBG4|A0A669KBG4_HUMAN,tr|A0A2R8YFV2|A0A2R8YFV2_HUMAN,tr|A0A669KAV7|A0A669KAV7_HUMAN,tr|M0QXA7|M0QXA7_HUMAN,tr|A0A669KBH9|A0A669KBH9_HUMAN,tr|B9EGQ5|B9EGQ5_HUMAN" 7 1083.4945 1.53 75979 4828 2 1083.495181 542.7545 Protein Wiz OS=Homo sapiens OX=9606 GN=WIZ PE=1 SV=2 4.53 1455.3 - 4.77E+06 - - - 0.6276 - 2.375 0.511 - 372 1 2 0 0.0007 12 0 0 0 1.33E+08 8.71E+07 - - - 5.091 0.9987 221125_WJC_METTL3_EV_vs_WT_F06.04829.04829.2 0.0517 14-Aug K.GAIENC[160.03]C[160.03]R.A sp|Q9NZI8|IF2B1_HUMAN 1 978.4011 1.33 75980 4829 2 978.401484 490.2078 Insulin-like growth factor 2 mRNA-binding protein 1 OS=Homo sapiens OX=9606 GN=IGF2BP1 PE=1 SV=2 5.99 1455.3 - 3.72E+06 - - - 0.3567 - 1.487 0.261 - 191.9 1 2 0 0.0003 8 0 0 0 1.91E+08 1.43E+08 - - - 2.1652 0.9907 221125_WJC_METTL3_EV_vs_WT_F06.04833.04833.2 0.0323 14-Jun K.DVPNTQPK[136.11].A sp|Q9Y5V3|MAGD1_HUMAN 1 905.4698 1.63 75982 4833 2 905.468521 453.7422 Melanoma-associated antigen D1 OS=Homo sapiens OX=9606 GN=MAGED1 PE=1 SV=3 5.84 1455.8 - 2.96E+06 - - - -1.4081 - 1.043 0.239 - 114.5 1 2 0 -0.0013 8 0 0 0 1.51E+08 9.26E+07 - - - 0.9328 0.9834 221125_WJC_METTL3_EV_vs_WT_F06.04834.04834.2 1.01 14-Jul K.RVTSIADR.L "sp|P60891|PRPS1_HUMAN,sp|P11908|PRPS2_HUMAN,tr|A0A2R8Y7H4|A0A2R8Y7H4_HUMAN,tr|B1ALA9|B1ALA9_HUMAN" 4 916.509 0.82 75983 4834 2 916.509282 459.2618 Ribose-phosphate pyrophosphokinase 1 OS=Homo sapiens OX=9606 GN=PRPS1 PE=1 SV=2 9.6 1455.8 - 2.69E+06 - - - 0.276 - 1.308 0.108 - 103.5 6 2 0 0.0003 8 0 0 0 1.15E+08 1.40E+08 - - - 0.3008 0.9944 221125_WJC_METTL3_EV_vs_WT_F06.04839.04839.2 0.322 14-Aug K.R[166.11]VTSIADR[166.11].L "sp|P60891|PRPS1_HUMAN,sp|P11908|PRPS2_HUMAN,tr|A0A2R8Y7H4|A0A2R8Y7H4_HUMAN,tr|B1ALA9|B1ALA9_HUMAN" 4 936.5256 0.84 75986 4839 2 936.52595 469.2701 Ribose-phosphate pyrophosphokinase 1 OS=Homo sapiens OX=9606 GN=PRPS1 PE=1 SV=2 9.6 1456.5 - 5.39E+06 - - - 0.4068 - 1.499 0.109 - 157.7 1 2 0 0.0004 8 0 0 0 1.11E+08 1.32E+08 - - - 1.0668 0.999 221125_WJC_METTL3_EV_vs_WT_F06.04840.04840.2 0.151 14-Aug R.SSGGYEPR[166.11].G "sp|P35637|FUS_HUMAN,tr|H3BNZ4|H3BNZ4_HUMAN,tr|H3BPE7|H3BPE7_HUMAN" 3 861.3856 0.49 75987 4840 2 861.386185 431.7001 RNA-binding protein FUS OS=Homo sapiens OX=9606 GN=FUS PE=1 SV=1 5.72 1456.6 - 1.23E+06 - - - 0.6606 - 1.541 0.293 - 288.4 1 2 0 0.0006 8 0 0 0 4.12E+07 8.40E+07 - - - 2.5091 0.9977 221125_WJC_METTL3_EV_vs_WT_F06.04841.04841.2 0.000214 18-Aug R.GQENGLDGTK.S "sp|Q14157|UBP2L_HUMAN,tr|Q5VU78|Q5VU78_HUMAN,tr|F8W726|F8W726_HUMAN,tr|Q5VU81|Q5VU81_HUMAN,tr|Q5VU79|Q5VU79_HUMAN,tr|Q5VU80|Q5VU80_HUMAN,tr|Q5VU77|Q5VU77_HUMAN" 7 1017.4727 2.16 75988 4841 2 1017.469717 509.7436 Ubiquitin-associated protein 2-like OS=Homo sapiens OX=9606 GN=UBAP2L PE=1 SV=2 4.37 1456.6 - 3.79E+06 - - - -2.9347 - 1.706 0.325 - 186.5 1 2 0 -0.003 10 0 0 0 3.78E+09 1.75E+09 - - - 2.9315 0.9973 221125_WJC_METTL3_EV_vs_WT_F06.04842.04842.2 0.034 16-Jul K.AVTDQTVSK[136.11].K sp|P38432|COIL_HUMAN 1 955.5066 1.12 75989 4842 2 955.507901 478.7606 Coilin OS=Homo sapiens OX=9606 GN=COIL PE=1 SV=1 5.88 1456.7 - 1.68E+06 - - - 1.3877 - 1.514 0.229 - 137.3 1 2 0 0.0013 9 0 0 0 4.96E+07 4.41E+07 - - - 1.9319 0.9274 221125_WJC_METTL3_EV_vs_WT_F06.04845.04845.2 4.87 12-May K.QEEQLQR.Q sp|O94766|B3GA3_HUMAN 1 929.4567 1.1 75990 4845 2 929.454719 465.7356 Galactosylgalactosylxylosylprotein 3-beta-glucuronosyltransferase 3 OS=Homo sapiens OX=9606 GN=B3GAT3 PE=1 SV=2 4.53 1457.1 - 2.41E+06 - - - -2.0872 - 1.127 0.056 - 123.9 1 2 0 -0.0019 7 0 0 0 6.54E+07 5.92E+07 - - - -0.1672 0.9276 221125_WJC_METTL3_EV_vs_WT_F06.04851.04851.2 8.46 12-Jun K.TIDQIHK[136.11].E "sp|Q04637|IF4G1_HUMAN,tr|H7C044|H7C044_HUMAN,tr|E7EUU4|E7EUU4_HUMAN,tr|E9PGM1|E9PGM1_HUMAN,tr|E7EX73|E7EX73_HUMAN,tr|A0A7I2Y1C3|A0A7I2Y1C3_HUMAN" 6 861.48 2.49 75994 4851 2 861.480261 431.7473 Eukaryotic translation initiation factor 4 gamma 1 OS=Homo sapiens OX=9606 GN=EIF4G1 PE=1 SV=4 6.41 1457.7 - 2.58E+06 - - - 0.3413 - 0.983 0.049 - 126.6 1 2 0 0.0003 7 0 0 0 3.12E+08 1.25E+08 - - - -0.6515 0.9972 221125_WJC_METTL3_EV_vs_WT_F06.04858.04858.2 0.618 14-Aug K.KVSVAVPK.K tr|A0A0A0MTS7|A0A0A0MTS7_HUMAN 1 826.5276 26.93 75999 4858 2 826.527108 414.2711 Titin OS=Homo sapiens OX=9606 GN=TTN PE=1 SV=1 10 1458.5 - 810074 - - - -0.6424 - 1.654 0.137 - 288.1 1 2 0 -0.0005 8 0 0 0 1.12E+08 4.15E+06 - - - 1.5703 0.9994 221125_WJC_METTL3_EV_vs_WT_F06.04859.04859.2 0.0428 14-Aug K.GAIENC[160.03]C[160.03]R[166.11].A sp|Q9NZI8|IF2B1_HUMAN 1 988.4094 1.27 76000 4859 2 988.408936 495.212 Insulin-like growth factor 2 mRNA-binding protein 1 OS=Homo sapiens OX=9606 GN=IGF2BP1 PE=1 SV=2 5.99 1458.6 - 6.18E+06 - - - -0.4745 - 1.614 0.331 - 181.1 1 2 0 -0.0005 8 0 0 0 1.91E+08 1.51E+08 - - - 2.9294 0.99 221125_WJC_METTL3_EV_vs_WT_F06.04861.04861.2 4.29E-05 16-Sep E.EANQAINPK.L "sp|Q92841|DDX17_HUMAN,sp|P17844|DDX5_HUMAN,tr|A0A5H1ZRQ2|A0A5H1ZRQ2_HUMAN,tr|J3KTA4|J3KTA4_HUMAN,tr|A0A0G2JLI4|A0A0G2JLI4_HUMAN,tr|A0A1X7SBZ2|A0A1X7SBZ2_HUMAN" 6 983.5036 1.72 76001 4861 2 983.503547 492.7591 Probable ATP-dependent RNA helicase DDX17 OS=Homo sapiens OX=9606 GN=DDX17 PE=1 SV=2 6.1 1458.8 - 1.07E+07 - - - -0.063 - 1.862 0.471 - 359.1 1 1 0 -0.0001 9 0 0 0 5.66E+09 3.28E+09 - - - 4.3183 0.9999 221125_WJC_METTL3_EV_vs_WT_F06.04866.04866.2 9.06E-07 18-Dec R.TPETTESQVK[136.11].D "sp|P82094|TMF1_HUMAN,tr|F8WF45|F8WF45_HUMAN,tr|A0A2R8Y7M0|A0A2R8Y7M0_HUMAN" 3 1126.5597 1.56 76005 4866 2 1126.559886 564.2871 TATA element modulatory factor OS=Homo sapiens OX=9606 GN=TMF1 PE=1 SV=2 4.53 1459.3 - 888094 - - - 0.1358 - 2.387 0.531 - 725.9 1 2 0 0.0002 10 0 0 0 6.77E+08 4.34E+08 - - - 5.3915 0.9979 221125_WJC_METTL3_EV_vs_WT_F06.04869.04869.2 0.0262 12-Aug R.REPLPSR.R "sp|Q96E39|RMXL1_HUMAN,sp|P38159|RBMX_HUMAN,sp|Q8IZ40|RCOR2_HUMAN,tr|H3BUY5|H3BUY5_HUMAN,tr|H3BT71|H3BT71_HUMAN,tr|H0Y6E7|H0Y6E7_HUMAN" 6 853.477 1.45 76007 4869 2 853.476603 427.7458 "RNA binding motif protein, X-linked-like-1 OS=Homo sapiens OX=9606 GN=RBMXL1 PE=1 SV=1" 9.6 1459.7 - 3.25E+07 - - - -0.4652 - 1.722 0.137 - 171.1 1 2 0 -0.0004 7 0 0 0 1.19E+09 8.21E+08 - - - 1.7748 0.9998 221125_WJC_METTL3_EV_vs_WT_F06.04874.04874.2 0.00433 18-Oct R.TPETTESQVK.D "sp|P82094|TMF1_HUMAN,tr|F8WF45|F8WF45_HUMAN,tr|A0A2R8Y7M0|A0A2R8Y7M0_HUMAN" 3 1118.5455 1.56 76011 4874 2 1118.544818 560.28 TATA element modulatory factor OS=Homo sapiens OX=9606 GN=TMF1 PE=1 SV=2 4.53 1460 - 3.05E+06 - - - -0.6392 - 2.134 0.433 - 369 1 2 0 -0.0007 10 0 0 0 6.77E+08 4.34E+08 - - - 4.3547 0.8993 221125_WJC_METTL3_EV_vs_WT_F06.04875.04875.2 27.5 12-Jun R.RLDPPSR.F "sp|Q8IX12|CCAR1_HUMAN,tr|F5H2E6|F5H2E6_HUMAN,tr|F5H1H2|F5H1H2_HUMAN,tr|A0A0C4DGG8|A0A0C4DGG8_HUMAN,tr|F5H3E1|F5H3E1_HUMAN" 5 839.4614 0.75 76012 4875 2 839.461523 420.738 Cell division cycle and apoptosis regulator protein 1 OS=Homo sapiens OX=9606 GN=CCAR1 PE=1 SV=2 9.6 1460.1 - 2.45E+06 - - - 0.2061 - 1.086 0.003 - 199.8 3 2 0 0.0002 7 0 0 0 7.82E+07 1.05E+08 - - - -0.8886 0.9988 221125_WJC_METTL3_EV_vs_WT_F06.04878.04878.2 0.304 12-Jun K.IHNFTSK.C "sp|Q9H2P0|ADNP_HUMAN,tr|A0A2R8Y6X0|A0A2R8Y6X0_HUMAN,tr|A0A669KBJ7|A0A669KBJ7_HUMAN" 3 845.4396 999 76013 4878 2 845.439323 423.7271 Activity-dependent neuroprotector homeobox protein OS=Homo sapiens OX=9606 GN=ADNP PE=1 SV=1 8.76 1460.4 - 1.31E+06 - - - -0.2709 - 1.583 0.23 - 144.9 1 2 0 -0.0002 7 0 0 0 2.52E+07 0.00E+00 - - - 2.1951 0.9984 221125_WJC_METTL3_EV_vs_WT_F06.04885.04885.2 0.0574 14-Aug R.NSSEQELR[166.11].L sp|Q9Y371|SHLB1_HUMAN 1 971.4548 1.33 76017 4885 2 971.453088 486.7347 Endophilin-B1 OS=Homo sapiens OX=9606 GN=SH3GLB1 PE=1 SV=1 4.53 1461.2 - 1.76E+06 - - - -1.7191 - 1.407 0.325 - 284.9 1 2 0 -0.0017 8 0 0 0 2.20E+08 1.65E+08 - - - 2.4708 0.9703 221125_WJC_METTL3_EV_vs_WT_F06.04888.04888.2 2.93 12-Jul K.R[166.11]SVLSPK[136.11].T "sp|Q8NCA5|FA98A_HUMAN,tr|E9PH82|E9PH82_HUMAN" 2 803.4984 1.23 76019 4888 2 803.497463 402.7565 Protein FAM98A OS=Homo sapiens OX=9606 GN=FAM98A PE=1 SV=2 11 1461.6 - 2.02E+06 - - - -1.1761 - 1.379 0.001 - 220.4 1 2 0 -0.0009 7 0 0 0 1.07E+08 8.69E+07 - - - 0.0663 0.9711 221125_WJC_METTL3_EV_vs_WT_F06.04890.04890.2 5.65 12-Jun R.R[166.11]EPLPSR[166.11].R "sp|Q96E39|RMXL1_HUMAN,sp|P38159|RBMX_HUMAN,sp|Q8IZ40|RCOR2_HUMAN,tr|H3BUY5|H3BUY5_HUMAN,tr|H3BT71|H3BT71_HUMAN,tr|H0Y6E7|H0Y6E7_HUMAN" 6 873.4935 1.44 76020 4890 2 873.492572 437.754 "RNA binding motif protein, X-linked-like-1 OS=Homo sapiens OX=9606 GN=RBMXL1 PE=1 SV=1" 9.6 1461.8 - 1.61E+07 - - - -1.1082 - 1.138 0.083 - 115.7 1 2 0 -0.001 7 0 0 0 1.19E+09 8.27E+08 - - - 0.0633 0.9936 221125_WJC_METTL3_EV_vs_WT_F06.04892.04892.2 2.17 14-Aug K.LQQEEVQK[136.11].K sp|Q86UP2|KTN1_HUMAN 1 1008.5331 3.14 76022 4892 2 1008.532962 505.2738 Kinectin OS=Homo sapiens OX=9606 GN=KTN1 PE=1 SV=1 4.53 1461.9 - 2.69E+06 - - - -0.1616 - 1.588 0.066 - 208.4 1 2 0 -0.0002 8 0 0 0 3.19E+08 1.01E+08 - - - 0.9232 0.999 221125_WJC_METTL3_EV_vs_WT_F06.04896.04896.2 0.0252 12-Jul R.NSTIPTK[136.11].Q "sp|P0DMV8|HS71A_HUMAN,sp|P34931|HS71L_HUMAN,sp|P0DMV9|HS71B_HUMAN,tr|Q53FA3|Q53FA3_HUMAN,tr|V9GZ37|V9GZ37_HUMAN,tr|A0A0G2JIW1|A0A0G2JIW1_HUMAN" 6 767.4269 0.13 76025 4896 2 767.426002 384.7207 Heat shock 70 kDa protein 1A OS=Homo sapiens OX=9606 GN=HSPA1A PE=1 SV=1 8.75 1462.3 - 5.83E+07 - - - -1.1297 - 1.522 0.299 - 236.1 1 2 0 -0.0009 7 0 0 0 1.08E+09 8.21E+09 - - - 2.58 0.9982 221125_WJC_METTL3_EV_vs_WT_F06.04898.04898.2 0.0398 12-Jun R.NSTIPTK.Q "sp|P0DMV8|HS71A_HUMAN,sp|P34931|HS71L_HUMAN,sp|P0DMV9|HS71B_HUMAN,tr|Q53FA3|Q53FA3_HUMAN,tr|V9GZ37|V9GZ37_HUMAN,tr|A0A0G2JIW1|A0A0G2JIW1_HUMAN" 6 759.4127 0.13 76026 4898 2 759.412267 380.7136 Heat shock 70 kDa protein 1A OS=Homo sapiens OX=9606 GN=HSPA1A PE=1 SV=1 8.75 1462.5 - 7.44E+06 - - - -0.5294 - 1.227 0.298 - 181.4 1 2 0 -0.0004 7 0 0 0 1.08E+09 8.21E+09 - - - 1.8901 0.9996 221125_WJC_METTL3_EV_vs_WT_F06.04899.04899.2 0.433 16-Aug R.NPQQQESLK[136.11].H sp|O95816|BAG2_HUMAN 1 1078.5498 0.34 76027 4899 2 1078.549651 540.2822 BAG family molecular chaperone regulator 2 OS=Homo sapiens OX=9606 GN=BAG2 PE=1 SV=1 6 1462.6 - 4.55E+06 - - - -0.1725 - 1.659 0.389 - 332.5 1 2 0 -0.0002 9 0 0 0 9.25E+07 2.69E+08 - - - 3.3786 0.8797 221125_WJC_METTL3_EV_vs_WT_F06.04902.04902.2 0.0606 14-Jun K.LFHSTDTK.S "sp|Q9Y508|RN114_HUMAN,tr|A0A096LP02|A0A096LP02_HUMAN,tr|A0A096LNV3|A0A096LNV3_HUMAN" 3 947.4712 0.91 76028 4902 2 947.465196 474.7429 E3 ubiquitin-protein ligase RNF114 OS=Homo sapiens OX=9606 GN=RNF114 PE=1 SV=1 6.74 1463 - 1.68E+06 - - - -6.3854 - 1.203 0.266 - 117.1 1 2 0 -0.006 8 0 0 0 4.59E+07 5.05E+07 - - - 1.5612 0.99 221125_WJC_METTL3_EV_vs_WT_F06.04904.04904.2 0.046 14-Aug R.SLKEQAIK.L sp|P15924|DESP_HUMAN 1 915.5389 102.06 76030 4904 2 915.537931 458.7767 Desmoplakin OS=Homo sapiens OX=9606 GN=DSP PE=1 SV=3 8.31 1463.1 - 2.50E+06 - - - -1.0933 - 1.615 0.295 - 211.2 1 2 1 -0.001 8 0 0 0 5.83E+07 5.71E+05 - - - 2.6652 0.9982 221125_WJC_METTL3_EV_vs_WT_F06.04910.04910.2 0.0059 16-Sep R.QVLHPEASR.K "sp|Q9H6T0|ESRP2_HUMAN,tr|J3QQJ9|J3QQJ9_HUMAN,tr|J3KRF2|J3KRF2_HUMAN" 3 1035.5461 1.3 76034 4910 2 1035.543914 518.7803 Epithelial splicing regulatory protein 2 OS=Homo sapiens OX=9606 GN=ESRP2 PE=1 SV=1 6.75 1463.9 - 752200 - - - -2.1515 - 1.583 0.303 - 310.5 1 2 0 -0.0022 9 0 0 0 1.63E+07 1.26E+07 - - - 2.6071 0.9602 221125_WJC_METTL3_EV_vs_WT_F06.04911.04911.2 3.3 14-May R.TQGSFSGR.C "sp|Q7Z7N9|T179B_HUMAN,tr|G3V185|G3V185_HUMAN" 2 838.3933 0.75 76035 4911 2 838.39372 420.2039 Transmembrane protein 179B OS=Homo sapiens OX=9606 GN=TMEM179B PE=1 SV=1 9.41 1463.9 - 2.42E+06 - - - 0.4652 - 0.968 0.147 - 92.4 4 2 0 0.0004 8 0 0 0 4.75E+07 6.34E+07 - - - -0.2404 0.9996 221125_WJC_METTL3_EV_vs_WT_F06.04923.04923.2 0.00223 14-Sep R.VTTEQYQK.A "sp|Q9NX63|MIC19_HUMAN,tr|F8WAR4|F8WAR4_HUMAN,tr|C9JRZ6|C9JRZ6_HUMAN" 3 995.4924 1.71 76042 4923 2 995.49198 498.7535 MICOS complex subunit MIC19 OS=Homo sapiens OX=9606 GN=CHCHD3 PE=1 SV=1 5.97 1465.4 - 1.19E+07 - - - -0.3968 - 1.977 0.309 - 299.8 1 2 0 -0.0004 8 0 0 0 1.38E+09 8.08E+08 - - - 3.3788 0.9993 221125_WJC_METTL3_EV_vs_WT_F06.04924.04924.2 0.000612 14-Aug K.EEDTSGYR.A sp|P15924|DESP_HUMAN 1 955.3883 12.17 76043 4924 2 955.387364 478.7014 Desmoplakin OS=Homo sapiens OX=9606 GN=DSP PE=1 SV=3 4.14 1465.4 - 5.01E+06 - - - -0.9839 - 1.706 0.29 - 382.7 1 2 0 -0.0009 8 0 0 0 1.14E+08 9.38E+06 - - - 2.7936 0.9846 221125_WJC_METTL3_EV_vs_WT_F06.04932.04932.2 0.881 14-Aug R.EQAEQTLK.Q sp|Q9UI36|DACH1_HUMAN 1 945.4767 2 76049 4932 2 945.479794 473.7456 Dachshund homolog 1 OS=Homo sapiens OX=9606 GN=DACH1 PE=1 SV=4 4.53 1466.4 - 527171 - - - 3.246 - 1.643 0.133 - 262.3 1 2 0 0.0031 8 0 0 0 7.86E+07 3.93E+07 - - - 1.5199 0.9998 221125_WJC_METTL3_EV_vs_WT_F06.04935.04935.2 0.151 16-Oct K.SAC[160.03]GVC[160.03]PGR[166.11].L sp|P49207|RL34_HUMAN 1 972.4145 1.01 76050 4935 2 972.414062 487.2145 60S ribosomal protein L34 OS=Homo sapiens OX=9606 GN=RPL34 PE=1 SV=3 7.8 1466.8 - 8.87E+06 - - - -0.4401 - 1.889 0.419 - 555.1 1 2 0 -0.0004 9 0 0 0 2.68E+08 2.64E+08 - - - 3.9757 0.9996 221125_WJC_METTL3_EV_vs_WT_F06.04937.04937.2 0.0044 16-Sep R.NPQQQESLK.H sp|O95816|BAG2_HUMAN 1 1070.5356 0.34 76051 4937 2 1070.535078 536.2751 BAG family molecular chaperone regulator 2 OS=Homo sapiens OX=9606 GN=BAG2 PE=1 SV=1 6 1467 - 3.11E+06 - - - -0.5222 - 1.759 0.342 - 426.1 1 2 0 -0.0006 9 0 0 0 9.27E+07 2.69E+08 - - - 3.2007 0.9622 221125_WJC_METTL3_EV_vs_WT_F06.04939.04939.2 3.72 12-Jun K.RSVLSPK.T "sp|Q8NCA5|FA98A_HUMAN,tr|E9PH82|E9PH82_HUMAN" 2 785.4759 1.23 76053 4939 2 785.47452 393.7452 Protein FAM98A OS=Homo sapiens OX=9606 GN=FAM98A PE=1 SV=2 11 1467.2 - 2.27E+06 - - - -1.8053 - 1.03 0.137 - 147.8 1 2 0 -0.0014 7 0 0 0 1.07E+08 8.69E+07 - - - 0.1461 0.9895 221125_WJC_METTL3_EV_vs_WT_F06.04949.04949.2 0.297 14-Sep K.ISQGNISK.A "sp|O76094|SRP72_HUMAN,tr|D6RDY6|D6RDY6_HUMAN" 2 845.4607 0.11 76059 4949 2 845.458338 423.7376 Signal recognition particle subunit SRP72 OS=Homo sapiens OX=9606 GN=SRP72 PE=1 SV=3 8.75 1468.3 - 1.40E+06 - - - -2.7713 - 1.757 0.107 - 169.7 1 2 0 -0.0023 8 0 0 0 3.47E+07 3.24E+08 - - - 1.5304 0.9985 221125_WJC_METTL3_EV_vs_WT_F06.04953.04953.2 1.55E-05 20-Dec R.AIGNNSATSPR.V "sp|Q9NYJ8|TAB2_HUMAN,tr|A0A1B0GV57|A0A1B0GV57_HUMAN" 2 1086.5418 2.45 76061 4953 2 1086.538676 544.2782 TGF-beta-activated kinase 1 and MAP3K7-binding protein 2 OS=Homo sapiens OX=9606 GN=TAB2 PE=1 SV=1 9.79 1468.8 - 541636 - - - -2.8614 - 2.253 0.28 - 505.2 1 2 0 -0.0031 11 0 0 0 3.07E+07 1.25E+07 - - - 3.3055 0.9981 221125_WJC_METTL3_EV_vs_WT_F06.04957.04957.2 0.116 14-Jul R.K[136.11]ILTTEGR[166.11].N sp|Q08211|DHX9_HUMAN 1 934.5567 0.81 76063 4957 2 934.555997 468.2856 ATP-dependent RNA helicase A OS=Homo sapiens OX=9606 GN=DHX9 PE=1 SV=4 8.75 1469.2 - 2.15E+06 - - - -0.6998 - 1.596 0.197 - 213.1 1 2 0 -0.0007 8 0 0 0 6.86E+07 8.48E+07 - - - 1.9058 0.9997 221125_WJC_METTL3_EV_vs_WT_F06.04962.04962.2 0.0156 14-Jul K.LEADYDKK.L sp|Q92900|RENT1_HUMAN 1 980.4815 12.42 76066 4962 2 980.480249 491.248 Regulator of nonsense transcripts 1 OS=Homo sapiens OX=9606 GN=UPF1 PE=1 SV=2 4.56 1469.7 - 1.96E+06 - - - -1.2514 - 1.586 0.472 - 148.9 1 2 0 -0.0012 8 0 0 0 4.78E+07 3.85E+06 - - - 3.9178 0.9981 221125_WJC_METTL3_EV_vs_WT_F06.04963.04963.2 0.0415 14-Aug R.EQAEQTLK[136.11].Q sp|Q9UI36|DACH1_HUMAN 1 953.4909 2.01 76067 4963 2 953.491005 477.7527 Dachshund homolog 1 OS=Homo sapiens OX=9606 GN=DACH1 PE=1 SV=4 4.53 1469.8 - 1.71E+06 - - - 0.0839 - 1.383 0.248 - 291.8 1 2 0 0.0001 8 0 0 0 7.81E+07 3.88E+07 - - - 1.8506 0.9991 221125_WJC_METTL3_EV_vs_WT_F06.04964.04964.2 0.0163 20-Oct R.AIGNNSATSPR[166.11].V "sp|Q9NYJ8|TAB2_HUMAN,tr|A0A1B0GV57|A0A1B0GV57_HUMAN" 2 1096.5501 2.54 76068 4964 2 1096.551058 549.2823 TGF-beta-activated kinase 1 and MAP3K7-binding protein 2 OS=Homo sapiens OX=9606 GN=TAB2 PE=1 SV=1 9.79 1469.9 - 563101 - - - 0.9147 - 1.795 0.282 - 327.2 1 2 0 0.001 11 0 0 0 3.07E+07 1.21E+07 - - - 2.7061 0.9492 221125_WJC_METTL3_EV_vs_WT_F06.04980.04980.2 2.73 14-May K.MDQPPQAK[136.11].K sp|P34932|HSP74_HUMAN 1 921.447 0.19 76078 4980 2 921.44565 461.7308 Heat shock 70 kDa protein 4 OS=Homo sapiens OX=9606 GN=HSPA4 PE=1 SV=4 5.59 1471.8 - 3.31E+06 - - - -1.413 - 0.893 0.206 - 52.4 9 2 0 -0.0013 8 0 0 0 3.03E+07 1.63E+08 - - - -0.2055 0.9981 221125_WJC_METTL3_EV_vs_WT_F06.04981.04981.2 0.000278 12-Jul R.GHYTIGK[136.11].E "sp|Q6PEY2|TBA3E_HUMAN,sp|P0DPH7|TBA3C_HUMAN,sp|Q71U36|TBA1A_HUMAN,sp|P0DPH8|TBA3D_HUMAN,sp|Q9H853|TBA4B_HUMAN,sp|P68366|TBA4A_HUMAN,sp|P68363|TBA1B_HUMAN,sp|Q9BQE3|TBA1C_HUMAN,tr|C9JJQ8|C9JJQ8_HUMAN,tr|F8VS66|F8VS66_HUMAN,tr|F8VWV9|F8VWV9_HUMAN,tr|F8VRZ4|F8VRZ4_HUMAN,tr|F8VVB9|F8VVB9_HUMAN,tr|C9JQ00|C9JQ00_HUMAN,tr|C9JEV8|C9JEV8_HUMAN,tr|A0A1W2PQM2|A0A1W2PQM2_HUMAN,tr|F5H5D3|F5H5D3_HUMAN,tr|C9JDL2|C9JDL2_HUMAN,tr|F8VQQ4|F8VQQ4_HUMAN" 19 782.4166 0.98 76079 4981 2 782.415387 392.2156 Tubulin alpha-3E chain OS=Homo sapiens OX=9606 GN=TUBA3E PE=1 SV=2 8.6 1471.8 - 1.19E+06 - - - -1.5989 - 1.643 0.224 - 272.4 1 2 0 -0.0013 7 0 0 0 2.90E+08 2.95E+08 - - - 2.2683 0.9569 221125_WJC_METTL3_EV_vs_WT_F06.04988.04988.2 2.81 12-Jun K.SQFEAQK[136.11].L sp|O75874|IDHC_HUMAN 1 844.417 1.26 76084 4988 2 844.416812 423.2158 Isocitrate dehydrogenase [NADP] cytoplasmic OS=Homo sapiens OX=9606 GN=IDH1 PE=1 SV=2 5.72 1472.6 - 888040 - - - -0.2605 - 1.13 0.031 - 125.5 1 2 0 -0.0002 7 0 0 0 2.49E+07 1.98E+07 - - - -0.3428 0.9577 221125_WJC_METTL3_EV_vs_WT_F06.04989.04989.2 0.0614 18-Oct R.QLAQAEQEGK.T sp|Q9BV73|CP250_HUMAN 1 1100.5462 0.63 76085 4989 2 1100.55016 551.2804 Centrosome-associated protein CEP250 OS=Homo sapiens OX=9606 GN=CEP250 PE=1 SV=2 4.53 1472.7 - 768362 - - - 3.5964 - 1.506 0.104 - 334.1 1 2 0 0.004 10 0 0 0 1.45E+07 2.32E+07 - - - 0.9508 0.9994 221125_WJC_METTL3_EV_vs_WT_F06.04990.04990.2 0.03 14-Jul R.FEC[160.03]AQC[160.03]QK[136.11].R sp|Q02086|SP2_HUMAN 1 1077.4463 0.85 76086 4990 2 1077.446999 539.7304 Transcription factor Sp2 OS=Homo sapiens OX=9606 GN=SP2 PE=1 SV=3 5.99 1472.9 - 475902 - - - 0.6478 - 1.372 0.399 - 136.9 1 2 0 0.0007 8 0 0 0 1.10E+07 1.29E+07 - - - 2.9416 0.9923 221125_WJC_METTL3_EV_vs_WT_F06.05005.05005.2 0.00674 12-Jul K.HNVIVGR[166.11].N sp|Q9UQE7|SMC3_HUMAN 1 803.4641 0.68 76096 5005 2 803.462935 402.7393 Structural maintenance of chromosomes protein 3 OS=Homo sapiens OX=9606 GN=SMC3 PE=1 SV=2 9.76 1474.4 - 2.01E+06 - - - -1.501 - 1.527 0.098 - 114 1 2 0 -0.0012 7 0 0 0 7.13E+07 1.04E+08 - - - 1.1057 0.9987 221125_WJC_METTL3_EV_vs_WT_F06.05008.05008.2 0.285 13/18 R.QLAEGTAQQR[166.11].L sp|Q15149|PLEC_HUMAN 1 1110.5657 2.29 76099 5008 2 1110.565542 556.2901 Plectin OS=Homo sapiens OX=9606 GN=PLEC PE=1 SV=3 6 1474.7 - 534558 - - - -0.1468 - 2.111 0.135 - 996 1 2 0 -0.0002 10 0 0 0 5.22E+07 2.28E+07 - - - 2.1236 0.9898 221125_WJC_METTL3_EV_vs_WT_F06.05014.05014.2 3.32 12-Aug R.R[166.11]IDEINK[136.11].E "sp|Q14683|SMC1A_HUMAN,sp|P55008|AIF1_HUMAN,tr|Q5STX8|Q5STX8_HUMAN,tr|G8JLG1|G8JLG1_HUMAN,tr|A0A6Q8PHC3|A0A6Q8PHC3_HUMAN" 5 904.5097 0.96 76104 5014 2 904.508306 453.2621 Structural maintenance of chromosomes protein 1A OS=Homo sapiens OX=9606 GN=SMC1A PE=1 SV=2 6.07 1475.3 - 2.35E+06 - - - -1.5423 - 1.573 0.061 - 292.9 1 2 0 -0.0014 7 0 0 0 6.47E+07 6.73E+07 - - - 0.9264 0.995 221125_WJC_METTL3_EV_vs_WT_F06.05016.05016.2 0.522 12-Jun K.K[136.11]QLDSLR[166.11].E "sp|Q86U44|MTA70_HUMAN,tr|B4E349|B4E349_HUMAN,tr|F5H6D8|F5H6D8_HUMAN,tr|B4DTN4|B4DTN4_HUMAN" 4 876.5148 0.4 76106 5016 2 876.51446 439.2647 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 8.75 1475.4 - 1.54E+06 - - - -0.3719 - 1.401 0.135 - 195.3 1 2 0 -0.0003 7 0 0 0 1.62E+07 4.02E+07 - - - 1.1064 0.9999 221125_WJC_METTL3_EV_vs_WT_F06.05018.05018.2 0.000529 22-Dec K.GLAAEDSGGDSK[136.11].D sp|P41227|NAA10_HUMAN 1 1113.5029 0.74 76108 5018 2 1113.503478 557.7587 N-alpha-acetyltransferase 10 OS=Homo sapiens OX=9606 GN=NAA10 PE=1 SV=1 4.03 1475.6 - 942608 - - - 0.4769 - 2.533 0.486 - 471.9 1 2 0 0.0005 12 0 0 0 3.95E+07 5.33E+07 - - - 5.0759 0.9996 221125_WJC_METTL3_EV_vs_WT_F06.05020.05020.2 0.00314 16-Aug R.TAPSGSEYR[166.11].H "sp|O43660|PLRG1_HUMAN,tr|D6RA26|D6RA26_HUMAN" 2 976.4489 1.09 76110 5020 2 976.448174 489.2317 Pleiotropic regulator 1 OS=Homo sapiens OX=9606 GN=PLRG1 PE=1 SV=1 5.66 1475.8 - 717254 - - - -0.7886 - 1.664 0.372 - 258.3 1 2 0 -0.0008 9 0 0 0 4.81E+07 4.40E+07 - - - 3.2616 1 221125_WJC_METTL3_EV_vs_WT_F06.05021.05021.2 0.000143 13/22 K.GLAAEDSGGDSK.D sp|P41227|NAA10_HUMAN 1 1105.4887 0.73 76111 5021 2 1105.487958 553.7516 N-alpha-acetyltransferase 10 OS=Homo sapiens OX=9606 GN=NAA10 PE=1 SV=1 4.03 1475.9 - 489933 - - - -0.7137 - 2.526 0.591 - 587.8 1 2 0 -0.0008 12 0 0 0 3.89E+07 5.33E+07 - - - 5.844 0.9991 221125_WJC_METTL3_EV_vs_WT_F06.05026.05026.2 0.000797 12-Aug R.GHYTIGK.E "sp|Q6PEY2|TBA3E_HUMAN,sp|P0DPH7|TBA3C_HUMAN,sp|Q71U36|TBA1A_HUMAN,sp|P0DPH8|TBA3D_HUMAN,sp|Q9H853|TBA4B_HUMAN,sp|P68366|TBA4A_HUMAN,sp|P68363|TBA1B_HUMAN,sp|Q9BQE3|TBA1C_HUMAN,tr|C9JJQ8|C9JJQ8_HUMAN,tr|F8VS66|F8VS66_HUMAN,tr|F8VWV9|F8VWV9_HUMAN,tr|F8VRZ4|F8VRZ4_HUMAN,tr|F8VVB9|F8VVB9_HUMAN,tr|C9JQ00|C9JQ00_HUMAN,tr|C9JEV8|C9JEV8_HUMAN,tr|A0A1W2PQM2|A0A1W2PQM2_HUMAN,tr|F5H5D3|F5H5D3_HUMAN,tr|C9JDL2|C9JDL2_HUMAN,tr|F8VQQ4|F8VQQ4_HUMAN" 19 774.4024 0.6 76114 5026 2 774.402248 388.2085 Tubulin alpha-3E chain OS=Homo sapiens OX=9606 GN=TUBA3E PE=1 SV=2 8.6 1476.6 - 1.18E+07 - - - -0.2454 - 1.832 0.204 - 400.5 1 2 0 -0.0002 7 0 0 0 1.59E+08 2.63E+08 - - - 2.466 0.9937 221125_WJC_METTL3_EV_vs_WT_F06.05029.05029.2 2.02E-06 22-Nov L.AALGGNSSPSAK.D sp|P05387|RLA2_HUMAN 1 1058.5356 1.36 76117 5029 2 1058.535756 530.2751 60S acidic ribosomal protein P2 OS=Homo sapiens OX=9606 GN=RPLP2 PE=1 SV=1 8.8 1476.7 - 3.34E+06 - - - 0.1124 - 2.437 0.508 - 289 1 1 0 0.0001 12 0 0 0 1.57E+08 1.16E+08 - - - 5.1368 0.9845 221125_WJC_METTL3_EV_vs_WT_F06.05030.05030.2 0.00141 22-Oct L.AALGGNSSPSAK[136.11].D sp|P05387|RLA2_HUMAN 1 1066.5498 1.35 76118 5030 2 1066.550645 534.2822 60S acidic ribosomal protein P2 OS=Homo sapiens OX=9606 GN=RPLP2 PE=1 SV=1 8.8 1476.8 - 2.43E+06 - - - 0.7576 - 2.222 0.381 - 201.1 1 1 0 0.0008 12 0 0 0 1.57E+08 1.16E+08 - - - 3.9556 0.9939 221125_WJC_METTL3_EV_vs_WT_F06.05031.05031.2 0.382 16-Aug K.LHGTVVEGR[166.11].K "sp|O43251|RFOX2_HUMAN,sp|Q9NWB1|RFOX1_HUMAN,tr|A0A6Q8PGE0|A0A6Q8PGE0_HUMAN,tr|A0A6Q8PH77|A0A6Q8PH77_HUMAN,tr|A0A286YEU2|A0A286YEU2_HUMAN,tr|A0A087X2B1|A0A087X2B1_HUMAN,tr|F8VR27|F8VR27_HUMAN,tr|B7Z1U7|B7Z1U7_HUMAN,tr|B0QYV1|B0QYV1_HUMAN,tr|A0A6Q8PHA3|A0A6Q8PHA3_HUMAN,tr|F8VZY7|F8VZY7_HUMAN,tr|B0QYY4|B0QYY4_HUMAN,tr|J3KNW3|J3KNW3_HUMAN,tr|F8VZG9|F8VZG9_HUMAN,tr|F8VRS4|F8VRS4_HUMAN,tr|A0A6Q8PFM4|A0A6Q8PFM4_HUMAN,tr|S4R469|S4R469_HUMAN,tr|A0A804HKG7|A0A804HKG7_HUMAN,tr|A0A0G2JRD1|A0A0G2JRD1_HUMAN,tr|A0A0G2JRA5|A0A0G2JRA5_HUMAN,tr|A0A804HJM2|A0A804HJM2_HUMAN,tr|I3L1D4|I3L1D4_HUMAN,tr|S4R3K7|S4R3K7_HUMAN" 23 976.5329 0.93 76119 5031 2 976.532326 489.2738 RNA binding protein fox-1 homolog 2 OS=Homo sapiens OX=9606 GN=RBFOX2 PE=1 SV=3 6.75 1476.9 - 1.53E+06 - - - -0.638 - 1.324 0.155 - 297.4 1 2 0 -0.0006 9 0 0 0 2.73E+08 2.92E+08 - - - 0.9976 0.9997 221125_WJC_METTL3_EV_vs_WT_F06.05037.05037.2 0.000102 12-Aug K.HNVIVGR.N sp|Q9UQE7|SMC3_HUMAN 1 793.4559 0.68 76123 5037 2 793.456663 397.7352 Structural maintenance of chromosomes protein 3 OS=Homo sapiens OX=9606 GN=SMC3 PE=1 SV=2 9.76 1477.6 - 4.62E+06 - - - 0.9982 - 1.728 0.458 - 187.1 1 2 0 0.0008 7 0 0 0 7.07E+07 1.04E+08 - - - 4.1566 0.9956 221125_WJC_METTL3_EV_vs_WT_F06.05038.05038.2 0.0381 14-Jun K.EVANLKPK.S sp|O00267|SPT5H_HUMAN 1 897.5284 1.47 76124 5038 2 897.528022 449.7715 Transcription elongation factor SPT5 OS=Homo sapiens OX=9606 GN=SUPT5H PE=1 SV=1 8.69 1477.7 - 1.37E+06 - - - -0.3844 - 1.273 0.194 - 142.2 1 2 0 -0.0003 8 0 0 0 4.13E+07 2.80E+07 - - - 1.2018 0.9989 221125_WJC_METTL3_EV_vs_WT_F06.05040.05040.2 0.0129 14-Sep R.NQQAELC[160.03]K[136.11].N "sp|Q99697|PITX2_HUMAN,tr|D6RFI4|D6RFI4_HUMAN,tr|D6RBG8|D6RBG8_HUMAN" 3 997.4742 1.71 76126 5040 2 997.47439 499.7444 Pituitary homeobox 2 OS=Homo sapiens OX=9606 GN=PITX2 PE=1 SV=2 5.99 1477.8 - 1.14E+06 - - - 0.1604 - 1.622 0.239 - 291.6 1 2 0 0.0002 8 0 0 0 3.87E+07 2.27E+07 - - - 2.2649 0.9994 221125_WJC_METTL3_EV_vs_WT_F06.05041.05041.2 0.0046 18-Nov R.VIHAIANSGK.L "sp|O95453|PARN_HUMAN,tr|A0A494C0Q6|A0A494C0Q6_HUMAN,tr|A0A494BZW7|A0A494BZW7_HUMAN,tr|A0A494C0Q2|A0A494C0Q2_HUMAN,tr|A0A494BZU6|A0A494BZU6_HUMAN,tr|A0A494C1G3|A0A494C1G3_HUMAN,tr|A0A494C002|A0A494C002_HUMAN,tr|A0A494C1K5|A0A494C1K5_HUMAN,tr|A0A494C156|A0A494C156_HUMAN,tr|A0A494C1N1|A0A494C1N1_HUMAN,tr|A0A494C0W0|A0A494C0W0_HUMAN,tr|A0A494C0P9|A0A494C0P9_HUMAN,tr|A0A494C0K5|A0A494C0K5_HUMAN,tr|H3BRK1|H3BRK1_HUMAN" 14 1008.5716 6.91 76127 5041 2 1008.570347 505.2931 Poly(A)-specific ribonuclease PARN OS=Homo sapiens OX=9606 GN=PARN PE=1 SV=1 8.73 1477.9 - 951105 - - - -1.2711 - 1.669 0.355 - 440.6 1 2 0 -0.0013 10 0 0 0 1.20E+07 1.74E+06 - - - 3.0924 0.9998 221125_WJC_METTL3_EV_vs_WT_F06.05046.05046.2 0.000235 18-Sep K.YETGPGGTSR.G sp|Q7Z417|NUFP2_HUMAN 1 1023.4621 0.34 76131 5046 2 1023.462003 512.7383 Nuclear fragile X mental retardation-interacting protein 2 OS=Homo sapiens OX=9606 GN=NUFIP2 PE=1 SV=1 6 1478.5 - 2.41E+06 - - - -0.1319 - 1.85 0.465 - 249.5 1 2 0 -0.0001 10 0 0 0 6.13E+07 1.79E+08 - - - 4.1926 0.9681 221125_WJC_METTL3_EV_vs_WT_F06.05050.05050.2 1.44 12-Jun R.YSGGNYR[166.11].D sp|P98179|RBM3_HUMAN 1 825.3645 0.93 76134 5050 2 825.364264 413.6895 RNA-binding protein 3 OS=Homo sapiens OX=9606 GN=RBM3 PE=1 SV=1 8.59 1478.8 - 1.30E+06 - - - -0.269 - 0.972 0.122 - 100.5 1 2 0 -0.0002 7 0 0 0 1.59E+07 1.71E+07 - - - -0.148 0.9979 221125_WJC_METTL3_EV_vs_WT_F06.05054.05054.2 0.215 16-Aug K.LHGTVVEGR.K "sp|O43251|RFOX2_HUMAN,sp|Q9NWB1|RFOX1_HUMAN,tr|A0A6Q8PGE0|A0A6Q8PGE0_HUMAN,tr|A0A6Q8PH77|A0A6Q8PH77_HUMAN,tr|A0A286YEU2|A0A286YEU2_HUMAN,tr|A0A087X2B1|A0A087X2B1_HUMAN,tr|F8VR27|F8VR27_HUMAN,tr|B7Z1U7|B7Z1U7_HUMAN,tr|B0QYV1|B0QYV1_HUMAN,tr|A0A6Q8PHA3|A0A6Q8PHA3_HUMAN,tr|F8VZY7|F8VZY7_HUMAN,tr|B0QYY4|B0QYY4_HUMAN,tr|J3KNW3|J3KNW3_HUMAN,tr|F8VZG9|F8VZG9_HUMAN,tr|F8VRS4|F8VRS4_HUMAN,tr|A0A6Q8PFM4|A0A6Q8PFM4_HUMAN,tr|S4R469|S4R469_HUMAN,tr|A0A804HKG7|A0A804HKG7_HUMAN,tr|A0A0G2JRD1|A0A0G2JRD1_HUMAN,tr|A0A0G2JRA5|A0A0G2JRA5_HUMAN,tr|A0A804HJM2|A0A804HJM2_HUMAN,tr|I3L1D4|I3L1D4_HUMAN,tr|S4R3K7|S4R3K7_HUMAN" 23 966.5247 0.96 76136 5054 2 966.524869 484.2696 RNA binding protein fox-1 homolog 2 OS=Homo sapiens OX=9606 GN=RBFOX2 PE=1 SV=3 6.75 1479.3 - 1.59E+07 - - - 0.1966 - 1.344 0.255 - 243.4 1 2 0 0.0002 9 0 0 0 2.72E+08 2.83E+08 - - - 1.7797 0.9998 221125_WJC_METTL3_EV_vs_WT_F06.05055.05055.2 0.0152 20-Aug K.SATEQSGTGIR[166.11].S "sp|O95831|AIFM1_HUMAN,tr|A0A6Q8PHJ9|A0A6Q8PHJ9_HUMAN,tr|E9PMA0|E9PMA0_HUMAN,tr|A0A7I2PK44|A0A7I2PK44_HUMAN,tr|A0A6Q8PG15|A0A6Q8PG15_HUMAN,tr|A0A6Q8PHJ4|A0A6Q8PHJ4_HUMAN,tr|A0A6Q8PHC0|A0A6Q8PHC0_HUMAN,tr|A0A6Q8PFM5|A0A6Q8PFM5_HUMAN" 8 1115.5446 0.87 76137 5055 2 1115.544236 558.7796 "Apoptosis-inducing factor 1, mitochondrial OS=Homo sapiens OX=9606 GN=AIFM1 PE=1 SV=1" 5.72 1479.3 - 4.49E+06 - - - -0.3586 - 1.908 0.426 - 254.2 1 2 0 -0.0004 11 0 0 0 1.14E+08 1.30E+08 - - - 3.935 0.9568 221125_WJC_METTL3_EV_vs_WT_F06.05059.05059.2 0.871 12-May R.KSGMAFK.S tr|A8MXP9|A8MXP9_HUMAN 1 767.4 0.49 76139 5059 2 767.39978 384.7073 Matrin-3 OS=Homo sapiens OX=9606 GN=MATR3 PE=1 SV=1 10 1479.8 - 3.10E+06 - - - -0.2802 - 1.02 0.093 - 93.5 2 2 0 -0.0002 7 0 0 0 5.96E+07 1.22E+08 - - - -0.3439 0.9999 221125_WJC_METTL3_EV_vs_WT_F06.05061.05061.2 8.00E-05 20-Oct K.SATEQSGTGIR.S "sp|O95831|AIFM1_HUMAN,tr|A0A6Q8PHJ9|A0A6Q8PHJ9_HUMAN,tr|E9PMA0|E9PMA0_HUMAN,tr|A0A7I2PK44|A0A7I2PK44_HUMAN,tr|A0A6Q8PG15|A0A6Q8PG15_HUMAN,tr|A0A6Q8PHJ4|A0A6Q8PHJ4_HUMAN,tr|A0A6Q8PHC0|A0A6Q8PHC0_HUMAN,tr|A0A6Q8PFM5|A0A6Q8PFM5_HUMAN" 8 1105.5364 1.01 76141 5061 2 1105.536687 553.7755 "Apoptosis-inducing factor 1, mitochondrial OS=Homo sapiens OX=9606 GN=AIFM1 PE=1 SV=1" 5.72 1479.9 - 3.57E+06 - - - 0.2904 - 2.07 0.516 - 389.3 1 2 0 0.0003 11 0 0 0 1.32E+08 1.31E+08 - - - 4.8203 0.9992 221125_WJC_METTL3_EV_vs_WT_F06.05062.05062.2 0.0276 14-Aug R.SETYVNGK.R "sp|O60333|KIF1B_HUMAN,tr|A0A087WWA3|A0A087WWA3_HUMAN,tr|Q4R9M9|Q4R9M9_HUMAN" 3 896.424 0.9 76142 5062 2 896.424748 449.2193 Kinesin-like protein KIF1B OS=Homo sapiens OX=9606 GN=KIF1B PE=1 SV=5 5.72 1480 - 1.85E+06 - - - 0.8768 - 1.6 0.32 - 287.7 1 2 0 0.0008 8 0 0 0 1.23E+07 1.37E+07 - - - 2.8218 0.9987 221125_WJC_METTL3_EV_vs_WT_F06.05063.05063.2 0.00185 16-Sep K.QLEEEDGSR[166.11].D sp|Q9Y678|COPG1_HUMAN 1 1071.4708 0.56 76143 5063 2 1071.47061 536.7427 Coatomer subunit gamma-1 OS=Homo sapiens OX=9606 GN=COPG1 PE=1 SV=1 4 1480.1 - 473262 - - - -0.1792 - 1.652 0.227 - 278.8 1 2 0 -0.0002 9 0 0 0 4.87E+06 8.62E+06 - - - 2.1698 0.9982 221125_WJC_METTL3_EV_vs_WT_F06.05068.05068.2 0.0182 14-Aug R.NQQAELC[160.03]K.N "sp|Q99697|PITX2_HUMAN,tr|D6RFI4|D6RFI4_HUMAN,tr|D6RBG8|D6RBG8_HUMAN" 3 989.46 1.27 76146 5068 2 989.459191 495.7373 Pituitary homeobox 2 OS=Homo sapiens OX=9606 GN=PITX2 PE=1 SV=2 5.99 1480.7 - 2.11E+06 - - - -0.8479 - 1.54 0.221 - 295.1 1 2 0 -0.0008 8 0 0 0 4.01E+07 3.16E+07 - - - 1.9753 0.9969 221125_WJC_METTL3_EV_vs_WT_F06.05075.05075.2 0.0519 14-Jul R.DGFQHPAR.L "sp|Q8IX12|CCAR1_HUMAN,tr|F5H2E6|F5H2E6_HUMAN,tr|F5H1H2|F5H1H2_HUMAN,tr|A0A0C4DGG8|A0A0C4DGG8_HUMAN,tr|F5H3E1|F5H3E1_HUMAN" 5 926.4359 5.22 76151 5075 2 926.436747 464.2252 Cell division cycle and apoptosis regulator protein 1 OS=Homo sapiens OX=9606 GN=CCAR1 PE=1 SV=2 6.74 1481.5 - 6.18E+06 - - - 0.9531 - 1.281 0.253 - 232 1 2 0 0.0009 8 0 0 0 1.07E+08 2.05E+07 - - - 1.6563 0.9997 221125_WJC_METTL3_EV_vs_WT_F06.05076.05076.2 0.00901 20-Dec R.SGGGGGGGFGR.V "sp|P13647|K2C5_HUMAN,tr|F8VV57|F8VV57_HUMAN,tr|F8VU69|F8VU69_HUMAN" 3 864.3838 198.81 76152 5076 2 864.385333 433.1992 "Keratin, type II cytoskeletal 5 OS=Homo sapiens OX=9606 GN=KRT5 PE=1 SV=3" 9.47 1481.6 - 4.93E+06 - - - 1.7411 - 2.483 0.439 - 712.4 1 2 0 0.0015 11 0 0 0 5.77E+09 2.90E+07 - - - 4.7433 0.9997 221125_WJC_METTL3_EV_vs_WT_F06.05085.05085.2 0.000922 18-Nov R.IAGQVAAANK.K "sp|P39019|RS19_HUMAN,tr|A0A075B6E2|A0A075B6E2_HUMAN" 2 941.5294 1.24 76159 5085 2 941.5302 471.772 40S ribosomal protein S19 OS=Homo sapiens OX=9606 GN=RPS19 PE=1 SV=2 8.75 1482.3 - 6.24E+06 - - - 0.8178 - 2.203 0.373 - 326.4 1 2 0 0.0008 10 0 0 0 2.35E+08 1.90E+08 - - - 4.0004 0.9564 221125_WJC_METTL3_EV_vs_WT_F06.05086.05086.2 0.0858 16-Jul A.QGEDNSEIK[136.11].E "sp|Q9UBW5|BIN2_HUMAN,tr|S4R418|S4R418_HUMAN" 2 1026.4709 2.1 76160 5086 2 1026.47126 514.2427 Bridging integrator 2 OS=Homo sapiens OX=9606 GN=BIN2 PE=1 SV=3 4.14 1482.4 - 3.01E+06 - - - 0.3332 - 1.474 0.338 - 240.7 1 1 0 0.0003 9 0 0 0 5.80E+08 2.76E+08 - - - 2.6598 0.998 221125_WJC_METTL3_EV_vs_WT_F06.05087.05087.2 0.282 16-Jun K.LPQTSDDEK.K sp|Q9GZT3|SLIRP_HUMAN 1 1031.4771 1.24 76161 5087 2 1031.477541 516.7458 "SRA stem-loop-interacting RNA-binding protein, mitochondrial OS=Homo sapiens OX=9606 GN=SLIRP PE=1 SV=1" 4.03 1482.4 - 4.70E+06 - - - 0.4091 - 1.354 0.259 - 151.5 1 2 0 0.0004 9 0 0 0 5.87E+08 4.73E+08 - - - 1.8306 0.9983 221125_WJC_METTL3_EV_vs_WT_F06.05089.05089.2 0.163 12-Jul R.FTDEESR[166.11].V "sp|Q9NYF8|BCLF1_HUMAN,tr|H0YF00|H0YF00_HUMAN,tr|E9PKI6|E9PKI6_HUMAN,tr|A0A1W2PQ43|A0A1W2PQ43_HUMAN,tr|E9PK91|E9PK91_HUMAN,tr|E9PK09|E9PK09_HUMAN,tr|E9PQN2|E9PQN2_HUMAN" 7 892.3802 2.29 76163 5089 2 892.380052 447.1974 Bcl-2-associated transcription factor 1 OS=Homo sapiens OX=9606 GN=BCLAF1 PE=1 SV=2 4.14 1482.6 - 1.42E+06 - - - -0.1614 - 1.384 0.253 - 171.2 1 2 0 -0.0001 7 0 0 0 3.28E+08 1.43E+08 - - - 1.9393 0.8936 221125_WJC_METTL3_EV_vs_WT_F06.05091.05091.2 1.42 18-May K.TYIPPK[136.11]GETK[136.11].K "sp|B2RPK0|HGB1A_HUMAN,sp|P09429|HMGB1_HUMAN,tr|Q5T7C4|Q5T7C4_HUMAN" 3 1148.6412 2.99 76165 5091 2 1148.642717 575.3279 Putative high mobility group protein B1-like 1 OS=Homo sapiens OX=9606 GN=HMGB1P1 PE=5 SV=1 8.17 1482.8 - 193136 - - - 1.2989 - 1.219 0.174 - 68.3 1 2 1 0.0015 10 0 0 0 8.32E+06 2.79E+06 - - - 0.8785 0.9996 221125_WJC_METTL3_EV_vs_WT_F06.05092.05092.2 0.000514 24-Aug K.AEGAATEEEGTPK.E "sp|P80723|BASP1_HUMAN,tr|U3KQP0|U3KQP0_HUMAN" 2 1288.5783 2.51 76166 5092 2 1288.580568 645.2964 Brain acid soluble protein 1 OS=Homo sapiens OX=9606 GN=BASP1 PE=1 SV=2 4.09 1482.9 - 104627 - - - 1.7678 - 1.761 0.49 - 137.8 1 2 0 0.0023 13 0 0 0 1.40E+06 5.59E+05 - - - 4.1118 0.9942 221125_WJC_METTL3_EV_vs_WT_F06.05096.05096.2 0.27 14-Jul K.TFQGKPIK.A sp|Q92615|LAR4B_HUMAN 1 917.5335 1.18 76168 5096 2 917.533756 459.774 La-related protein 4B OS=Homo sapiens OX=9606 GN=LARP4B PE=1 SV=3 10 1483.3 - 9.39E+06 - - - 0.3313 - 1.112 0.226 - 135.9 1 2 0 0.0003 8 0 0 0 8.36E+08 7.09E+08 - - - 1.0303 0.9988 221125_WJC_METTL3_EV_vs_WT_F06.05097.05097.2 1.57 12-Jul R.FTDEESR.V "sp|Q9NYF8|BCLF1_HUMAN,tr|H0YF00|H0YF00_HUMAN,tr|E9PKI6|E9PKI6_HUMAN,tr|A0A1W2PQ43|A0A1W2PQ43_HUMAN,tr|E9PK91|E9PK91_HUMAN,tr|E9PK09|E9PK09_HUMAN,tr|E9PQN2|E9PQN2_HUMAN" 7 882.3719 2.3 76169 5097 2 882.371972 442.1932 Bcl-2-associated transcription factor 1 OS=Homo sapiens OX=9606 GN=BCLAF1 PE=1 SV=2 4.14 1483.4 - 6.27E+06 - - - 0.0521 - 1.515 0.25 - 173.5 1 2 0 0 7 0 0 0 3.27E+08 1.42E+08 - - - 2.2038 0.9995 221125_WJC_METTL3_EV_vs_WT_F06.05098.05098.2 0.0658 12-Nov R.K[136.11]GVITVK[136.11].D "sp|P10809|CH60_HUMAN,tr|A0A7I2V599|A0A7I2V599_HUMAN,tr|E7EXB4|E7EXB4_HUMAN,tr|A0A7I2YQ71|A0A7I2YQ71_HUMAN,tr|A0A7I2V5M1|A0A7I2V5M1_HUMAN,tr|A0A7I2V5K3|A0A7I2V5K3_HUMAN,tr|A0A7I2V369|A0A7I2V369_HUMAN" 7 759.5189 0.001 76170 5098 2 759.518971 380.7667 "60 kDa heat shock protein, mitochondrial OS=Homo sapiens OX=9606 GN=HSPD1 PE=1 SV=2" 10 1483.4 - 5.51E+06 - - - 0.0606 - 2.08 0.232 - 437 1 2 0 0 7 0 0 0 0.00E+00 1.29E+09 - - - 3.0751 0.9999 221125_WJC_METTL3_EV_vs_WT_F06.05099.05099.2 6.52E-05 16-Oct K.C[160.03]IAC[160.03]QNPGK[136.11].Q "sp|P49792|RBP2_HUMAN,sp|P49792|RBP2_HUMAN" 2 1054.4779 0.83 76171 5099 2 1054.478038 528.2462 E3 SUMO-protein ligase RanBP2 OS=Homo sapiens OX=9606 GN=RANBP2 PE=1 SV=2 8.06 1483.5 - 3.98E+06 - - - 0.0977 - 1.984 0.49 - 327.4 1 2 0 0.0001 9 0 0 0 6.94E+07 8.35E+07 - - - 4.6422 0.9979 221125_WJC_METTL3_EV_vs_WT_F06.05104.05104.2 0.613 14-Aug R.R[166.11]LLQQEEK[136.11].V sp|Q9BSC4|NOL10_HUMAN 1 1060.5996 0.48 76176 5104 2 1060.599936 531.3071 Nucleolar protein 10 OS=Homo sapiens OX=9606 GN=NOL10 PE=1 SV=1 6.14 1483.7 - 1.08E+06 - - - 0.3375 - 1.742 0.146 - 233.7 1 2 0 0.0004 8 0 0 0 5.68E+06 1.18E+07 - - - 1.7932 0.9982 221125_WJC_METTL3_EV_vs_WT_F06.05110.05110.2 0.0549 14-Jul K.GTNESLER[166.11].Q "sp|P08670|VIME_HUMAN,sp|P14136|GFAP_HUMAN,tr|A0A1W2PR46|A0A1W2PR46_HUMAN,tr|A0A1X7SBR3|A0A1X7SBR3_HUMAN,tr|A0A1W2PRT3|A0A1W2PRT3_HUMAN,tr|B0YJC5|B0YJC5_HUMAN,tr|B0YJC4|B0YJC4_HUMAN" 7 914.4333 1.99 76180 5110 2 914.433687 458.2239 Vimentin OS=Homo sapiens OX=9606 GN=VIM PE=1 SV=4 4.53 1484.4 - 6.64E+06 - - - 0.4298 - 1.657 0.188 - 358.7 1 2 0 0.0004 8 0 0 0 8.11E+08 4.07E+08 - - - 1.9525 0.9997 221125_WJC_METTL3_EV_vs_WT_F06.05111.05111.2 0.00166 16-Sep K.C[160.03]IAC[160.03]QNPGK.Q "sp|P49792|RBP2_HUMAN,sp|P49792|RBP2_HUMAN" 2 1046.4637 0.83 76181 5111 2 1046.464413 524.2391 E3 SUMO-protein ligase RanBP2 OS=Homo sapiens OX=9606 GN=RANBP2 PE=1 SV=2 8.06 1484.4 - 4.09E+06 - - - 0.6479 - 1.717 0.41 - 252.4 1 2 0 0.0007 9 0 0 0 6.94E+07 8.35E+07 - - - 3.633 0.9829 221125_WJC_METTL3_EV_vs_WT_F06.05119.05119.2 0.0733 18-Jul R.VAAPQDGSPR[166.11].V sp|Q9HD15|SRA1_HUMAN 1 1006.5071 2.59 76187 5119 2 1006.503722 504.2608 Steroid receptor RNA activator 1 OS=Homo sapiens OX=9606 GN=SRA1 PE=1 SV=1 5.81 1485.2 - 1.14E+06 - - - -3.384 - 1.517 0.204 - 123 3 2 0 -0.0034 10 0 0 0 2.18E+07 8.41E+06 - - - 1.4968 0.9957 221125_WJC_METTL3_EV_vs_WT_F06.05120.05120.2 2.32 14-Sep R.TDAISEEK[136.11].L "sp|Q9NR31|SAR1A_HUMAN,tr|H0Y5E8|H0Y5E8_HUMAN" 2 899.4327 1.15 76188 5120 2 899.43546 450.7236 GTP-binding protein SAR1a OS=Homo sapiens OX=9606 GN=SAR1A PE=1 SV=1 4.14 1485.2 - 2.48E+06 - - - 3.0219 - 1.736 0.235 - 341 1 2 0 0.0027 8 0 0 0 1.42E+08 1.23E+08 - - - 2.4394 0.9995 221125_WJC_METTL3_EV_vs_WT_F06.05124.05124.2 0.000335 16-Aug R.EAYPDGSSK.E sp|Q2TAY7|SMU1_HUMAN 1 952.4138 1.07 76190 5124 2 952.41313 477.2142 WD40 repeat-containing protein SMU1 OS=Homo sapiens OX=9606 GN=SMU1 PE=1 SV=2 4.37 1485.7 - 1.13E+07 - - - -0.694 - 1.403 0.406 - 162.4 1 2 0 -0.0007 9 0 0 0 1.75E+08 1.64E+08 - - - 3.0191 0.974 221125_WJC_METTL3_EV_vs_WT_F06.05125.05125.2 1.84 16-Jul K.EEEEK[136.11]PEAK[136.11].E "sp|A1A519|F170A_HUMAN,tr|D6RIE9|D6RIE9_HUMAN" 2 1103.5317 0.89 76191 5125 2 1103.531368 552.7731 Protein FAM170A OS=Homo sapiens OX=9606 GN=FAM170A PE=2 SV=1 4.33 1485.8 - 6.68E+06 - - - -0.3317 - 0.966 0.142 - 143.8 1 2 0 -0.0004 9 0 0 0 1.88E+08 2.12E+08 - - - -0.0104 0.9811 221125_WJC_METTL3_EV_vs_WT_F06.05136.05136.2 2.15 12-May R.DQEEEYK.S sp|Q8N1N4|K2C78_HUMAN 1 939.3822 24.95 76197 5136 2 939.38174 470.6984 "Keratin, type II cytoskeletal 78 OS=Homo sapiens OX=9606 GN=KRT78 PE=1 SV=2" 4 1486.9 - 8.72E+06 - - - -0.4428 - 1.158 0.095 - 137.6 1 2 0 -0.0004 7 0 0 0 1.38E+08 5.53E+06 - - - 0.2073 0.9625 221125_WJC_METTL3_EV_vs_WT_F06.05138.05138.2 0.0786 16-Oct R.LADKYEEAK.E "sp|Q99567|NUP88_HUMAN,tr|I3L4K7|I3L4K7_HUMAN,tr|J3KMX1|J3KMX1_HUMAN" 3 1065.5342 2.25 76199 5138 2 1065.537552 533.7744 Nuclear pore complex protein Nup88 OS=Homo sapiens OX=9606 GN=NUP88 PE=1 SV=2 4.68 1487.1 - 878340 - - - 3.1083 - 1.86 0.252 - 334.5 1 2 1 0.0033 9 0 0 0 7.47E+07 3.32E+07 - - - 2.6966 0.9989 221125_WJC_METTL3_EV_vs_WT_F06.05144.05144.2 0.0388 14-Sep R.TDAISEEK.L "sp|Q9NR31|SAR1A_HUMAN,tr|H0Y5E8|H0Y5E8_HUMAN" 2 891.4185 1.19 76202 5144 2 891.417034 446.7165 GTP-binding protein SAR1a OS=Homo sapiens OX=9606 GN=SAR1A PE=1 SV=1 4.14 1487.8 - 8.58E+06 - - - -1.6917 - 1.984 0.225 - 338.6 1 2 0 -0.0015 8 0 0 0 1.42E+08 1.19E+08 - - - 2.7687 0.9988 221125_WJC_METTL3_EV_vs_WT_F06.05148.05148.2 0.00725 16-Aug R.LTC[160.03]EEEEEK[136.11].L "sp|P51531|SMCA2_HUMAN,sp|P51532|SMCA4_HUMAN,tr|A0A2R8Y5K3|A0A2R8Y5K3_HUMAN,tr|A0A2R8Y7S2|A0A2R8Y7S2_HUMAN,tr|A0A2R8Y7F3|A0A2R8Y7F3_HUMAN,tr|A0A2R8YGG3|A0A2R8YGG3_HUMAN,tr|A0A0U1RQZ9|A0A0U1RQZ9_HUMAN,tr|A0A2R8Y523|A0A2R8Y523_HUMAN,tr|A0A2R8Y6V2|A0A2R8Y6V2_HUMAN,tr|A0A0U1RRG6|A0A0U1RRG6_HUMAN,tr|Q9HBD4|Q9HBD4_HUMAN,tr|K7EQF0|K7EQF0_HUMAN,tr|A0A2R8Y440|A0A2R8Y440_HUMAN,tr|F6VDE0|F6VDE0_HUMAN,tr|A0A2R8YFK5|A0A2R8YFK5_HUMAN,tr|A0A2R8YDA1|A0A2R8YDA1_HUMAN,tr|A0A2R8Y7Y7|A0A2R8Y7Y7_HUMAN,tr|A0A2R8YF58|A0A2R8YF58_HUMAN,tr|A0A2R8Y526|A0A2R8Y526_HUMAN,tr|K7EP28|K7EP28_HUMAN,tr|A0A2R8YG32|A0A2R8YG32_HUMAN,tr|A0A2R8Y6N0|A0A2R8Y6N0_HUMAN,tr|A0A2R8YF80|A0A2R8YF80_HUMAN,tr|A0A2R8Y4P4|A0A2R8Y4P4_HUMAN,tr|A0A2R8Y4C5|A0A2R8Y4C5_HUMAN" 25 1173.4951 0.72 76206 5148 2 1173.493484 587.7548 Probable global transcription activator SNF2L2 OS=Homo sapiens OX=9606 GN=SMARCA2 PE=1 SV=2 3.98 1488.2 - 447267 - - - -1.3634 - 1.7 0.269 - 212.7 1 2 0 -0.0016 9 0 0 0 2.77E+06 3.86E+06 - - - 2.5625 0.9978 221125_WJC_METTL3_EV_vs_WT_F06.05153.05153.2 0.0256 14-Jun K.SVPHEEYR.S "sp|Q9P2K5|MYEF2_HUMAN,tr|A0A0A0MR39|A0A0A0MR39_HUMAN,tr|A0A087WUT0|A0A087WUT0_HUMAN,tr|H0YN19|H0YN19_HUMAN,tr|A0A0A0MQW0|A0A0A0MQW0_HUMAN" 5 1015.4723 1.25 76209 5153 2 1015.47099 508.7434 Myelin expression factor 2 OS=Homo sapiens OX=9606 GN=MYEF2 PE=1 SV=3 5.38 1488.7 - 1.25E+07 - - - -1.2989 - 1.172 0.333 - 142.3 1 2 0 -0.0013 8 0 0 0 1.56E+08 1.25E+08 - - - 1.9788 0.9998 221125_WJC_METTL3_EV_vs_WT_F06.05154.05154.2 5.17E-05 18-Sep R.NPPGASTYNK[136.11].N "sp|Q9BUJ2|HNRL1_HUMAN,tr|A0A0A0MRA5|A0A0A0MRA5_HUMAN,tr|M0R3F1|M0R3F1_HUMAN,tr|B7Z4B8|B7Z4B8_HUMAN" 4 1055.5127 1.46 76210 5154 2 1055.511909 528.7636 Heterogeneous nuclear ribonucleoprotein U-like protein 1 OS=Homo sapiens OX=9606 GN=HNRNPUL1 PE=1 SV=2 8.59 1488.8 - 4.55E+06 - - - -0.7712 - 1.763 0.486 - 300.8 1 2 0 -0.0008 10 0 0 0 8.80E+08 6.03E+08 - - - 4.2131 0.9992 221125_WJC_METTL3_EV_vs_WT_F06.05155.05155.2 0.0665 14-Oct R.RVLDETAR.E sp|Q03252|LMNB2_HUMAN 1 958.5196 7.08 76211 5155 2 958.520361 480.2671 Lamin-B2 OS=Homo sapiens OX=9606 GN=LMNB2 PE=1 SV=4 6.07 1488.8 - 2.50E+06 - - - 0.8012 - 1.941 0.237 - 272.4 1 2 0 0.0008 8 0 0 0 1.86E+08 2.63E+07 - - - 2.7914 0.9921 221125_WJC_METTL3_EV_vs_WT_F06.05161.05161.2 2.02 12-Jul R.R[166.11]QLPVTR[166.11].T "sp|P52907|CAZA1_HUMAN,sp|P47755|CAZA2_HUMAN" 2 888.5408 1.19 76215 5161 2 888.540023 445.2777 F-actin-capping protein subunit alpha-1 OS=Homo sapiens OX=9606 GN=CAPZA1 PE=1 SV=3 12 1489.5 - 8.25E+06 - - - -0.9026 - 1.477 0.081 - 125.7 1 2 0 -0.0008 7 0 0 0 8.26E+07 6.95E+07 - - - 0.8748 1 221125_WJC_METTL3_EV_vs_WT_F06.05163.05163.2 9.30E-07 18-Nov A.C[160.03]MDSEAPGSK[136.11].D "sp|Q86U44|MTA70_HUMAN,tr|H0YFV6|H0YFV6_HUMAN" 2 1088.4358 0.01 76216 5163 2 1088.43521 545.2252 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 4.37 1489.6 - 3.44E+06 - - - -0.5375 - 2.087 0.657 - 377.3 1 1 0 -0.0006 10 0 0 0 8.83E+05 1.18E+08 - - - 5.9471 0.9998 221125_WJC_METTL3_EV_vs_WT_F06.05164.05164.2 0.0179 20-Oct K.AAATAEEPDPK.G "sp|Q99733|NP1L4_HUMAN,tr|A8MXH2|A8MXH2_HUMAN,tr|C9J6D1|C9J6D1_HUMAN,tr|E9PKT8|E9PKT8_HUMAN,tr|C9JZI7|C9JZI7_HUMAN,tr|H0YCI4|H0YCI4_HUMAN" 6 1098.5193 0.68 76217 5164 2 1098.519699 550.2669 Nucleosome assembly protein 1-like 4 OS=Homo sapiens OX=9606 GN=NAP1L4 PE=1 SV=1 4.14 1489.6 - 3.00E+06 - - - 0.3459 - 2.179 0.434 - 230.4 1 2 0 0.0004 11 0 0 0 7.21E+07 1.06E+08 - - - 4.3534 0.9552 221125_WJC_METTL3_EV_vs_WT_F06.05165.05165.2 0.0668 16-Sep K.SKGGVVGIK.V "sp|P04075|ALDOA_HUMAN,tr|H3BR04|H3BR04_HUMAN,tr|H3BMQ8|H3BMQ8_HUMAN,tr|H3BU78|H3BU78_HUMAN,tr|H3BQN4|H3BQN4_HUMAN,tr|H3BUH7|H3BUH7_HUMAN,tr|J3KPS3|J3KPS3_HUMAN,tr|H3BPS8|H3BPS8_HUMAN" 8 843.5178 1.93 76218 5165 2 843.514781 422.7662 Fructose-bisphosphate aldolase A OS=Homo sapiens OX=9606 GN=ALDOA PE=1 SV=2 10 1489.7 - 2.54E+06 - - - -3.5814 - 1.543 0.343 - 165.3 1 2 1 -0.003 9 0 0 0 4.53E+07 2.35E+07 - - - 2.8282 0.9989 221125_WJC_METTL3_EV_vs_WT_F06.05168.05168.2 0.393 12-Aug R.HSELLQK.V "sp|Q9Y2Q9|RT28_HUMAN,tr|E5RFT8|E5RFT8_HUMAN,tr|H7C5V3|H7C5V3_HUMAN" 3 853.4658 1.13 76220 5168 2 853.465533 427.7402 "28S ribosomal protein S28, mitochondrial OS=Homo sapiens OX=9606 GN=MRPS28 PE=1 SV=1" 6.75 1490 - 1.08E+07 - - - -0.2742 - 1.653 0.22 - 211 1 2 0 -0.0002 7 0 0 0 1.76E+08 1.56E+08 - - - 2.2583 0.9931 221125_WJC_METTL3_EV_vs_WT_F06.05170.05170.2 0.0179 16-Sep R.GK[136.11]EDALVTK[136.11].N "sp|P22087|FBRL_HUMAN,tr|M0R299|M0R299_HUMAN,tr|M0R0P1|M0R0P1_HUMAN,tr|M0R1H0|M0R1H0_HUMAN,tr|M0QXL5|M0QXL5_HUMAN,tr|M0R2Q4|M0R2Q4_HUMAN,tr|M0R2B0|M0R2B0_HUMAN,tr|M0R2U2|M0R2U2_HUMAN" 8 975.5572 0.82 76221 5170 2 975.556064 488.7859 rRNA 2'-O-methyltransferase fibrillarin OS=Homo sapiens OX=9606 GN=FBL PE=1 SV=2 6.07 1490.2 - 1.23E+07 - - - -1.1245 - 1.966 0.278 - 194 1 2 1 -0.0011 9 0 0 0 3.86E+08 4.69E+08 - - - 3.0497 0.9936 221125_WJC_METTL3_EV_vs_WT_F06.05171.05171.2 0.78 12-Jul R.RQLPVTR.T "sp|P52907|CAZA1_HUMAN,sp|P47755|CAZA2_HUMAN" 2 868.5243 1.19 76222 5171 2 868.524531 435.2694 F-actin-capping protein subunit alpha-1 OS=Homo sapiens OX=9606 GN=CAPZA1 PE=1 SV=3 12 1490.3 - 7.89E+06 - - - 0.2832 - 1.218 0.174 - 127.5 1 2 0 0.0002 7 0 0 0 8.26E+07 6.95E+07 - - - 0.951 0.9985 221125_WJC_METTL3_EV_vs_WT_F06.05172.05172.2 0.0823 14-Jun K.GTNESLER.Q "sp|P08670|VIME_HUMAN,sp|P14136|GFAP_HUMAN,tr|A0A1W2PR46|A0A1W2PR46_HUMAN,tr|A0A1X7SBR3|A0A1X7SBR3_HUMAN,tr|A0A1W2PRT3|A0A1W2PRT3_HUMAN,tr|B0YJC5|B0YJC5_HUMAN,tr|B0YJC4|B0YJC4_HUMAN" 7 904.425 1.99 76223 5172 2 904.42435 453.2198 Vimentin OS=Homo sapiens OX=9606 GN=VIM PE=1 SV=4 4.53 1490.3 - 1.38E+07 - - - -0.7452 - 1.53 0.237 - 181.9 1 2 0 -0.0007 8 0 0 0 8.11E+08 4.07E+08 - - - 2.0739 0.9009 221125_WJC_METTL3_EV_vs_WT_F06.05173.05173.2 1.72 12-Sep Q.K[136.11]EITQLK[136.11].H "sp|Q9UGC7|RF1ML_HUMAN,sp|P07910|HNRPC_HUMAN,sp|Q86SE5|RALYL_HUMAN,tr|B4DY08|B4DY08_HUMAN,tr|E5RJ39|E5RJ39_HUMAN,tr|G3V5V7|G3V5V7_HUMAN,tr|B3KT61|B3KT61_HUMAN,tr|B2R5W2|B2R5W2_HUMAN,tr|G3V4C1|G3V4C1_HUMAN,tr|G3V576|G3V576_HUMAN,tr|G3V2D6|G3V2D6_HUMAN,tr|G3V4W0|G3V4W0_HUMAN,tr|G3V2Q1|G3V2Q1_HUMAN" 13 874.5459 1.21 76224 5173 2 874.545136 438.2802 "Peptide chain release factor 1-like, mitochondrial OS=Homo sapiens OX=9606 GN=MTRF1L PE=1 SV=1" 8.59 1490.4 - 4.81E+06 - - - -0.837 - 1.903 0.119 - 253.5 1 1 0 -0.0007 7 0 0 0 8.81E+07 7.31E+07 - - - 1.9585 0.995 221125_WJC_METTL3_EV_vs_WT_F06.05175.05175.2 0.23 20-Dec K.LK[136.11]SDTAAAAVR[166.11].Q sp|P22314|UBA1_HUMAN 1 1119.6367 0.74 76226 5175 2 1119.63569 560.8256 Ubiquitin-like modifier-activating enzyme 1 OS=Homo sapiens OX=9606 GN=UBA1 PE=1 SV=3 8.75 1490.5 - 3.15E+06 - - - -0.8949 - 2.145 0.294 - 289.5 1 2 1 -0.001 11 0 0 0 2.08E+07 2.79E+07 - - - 3.2766 0.9992 221125_WJC_METTL3_EV_vs_WT_F06.05177.05177.2 0.00253 18-Sep R.TDEVPAGGSR.S "sp|Q9UJV9|DDX41_HUMAN,tr|A0A499FJW5|A0A499FJW5_HUMAN,tr|D6RD33|D6RD33_HUMAN,tr|D6RGI7|D6RGI7_HUMAN" 4 987.4621 0.45 76228 5177 2 987.461744 494.7383 Probable ATP-dependent RNA helicase DDX41 OS=Homo sapiens OX=9606 GN=DDX41 PE=1 SV=2 4.37 1490.6 - 1.80E+06 - - - -0.399 - 1.831 0.252 - 311.5 1 2 0 -0.0004 10 0 0 0 2.04E+07 4.52E+07 - - - 2.5905 0.9324 221125_WJC_METTL3_EV_vs_WT_F06.05183.05183.2 0.122 16-Sep S.TISSNVASK.A sp|P35908|K22E_HUMAN 1 905.4818 14.41 76232 5183 2 905.480425 453.7482 "Keratin, type II cytoskeletal 2 epidermal OS=Homo sapiens OX=9606 GN=KRT2 PE=1 SV=2" 8.41 1491.2 - 5.11E+06 - - - -1.5307 - 1.433 0.343 - 183.8 1 1 0 -0.0014 9 0 0 0 1.18E+08 8.19E+06 - - - 2.6148 0.992 221125_WJC_METTL3_EV_vs_WT_F06.05185.05185.2 0.0568 12-Apr K.C[160.03]DLQEQR.R "sp|Q9NYR9|KBRS2_HUMAN,tr|K7ERG2|K7ERG2_HUMAN,tr|H7BXP1|H7BXP1_HUMAN" 3 947.4131 1.8 76234 5185 2 947.411554 474.7138 NF-kappa-B inhibitor-interacting Ras-like protein 2 OS=Homo sapiens OX=9606 GN=NKIRAS2 PE=1 SV=1 4.37 1491.3 - 1.38E+06 - - - -1.6107 - 1.226 0.224 - 55.8 3 2 0 -0.0015 7 0 0 0 1.75E+07 9.74E+06 - - - 1.1275 0.9878 221125_WJC_METTL3_EV_vs_WT_F06.05186.05186.2 0.561 14-May R.RLTPQAVK.L "sp|P05198|IF2A_HUMAN,tr|H0YJS4|H0YJS4_HUMAN,tr|G3V4T5|G3V4T5_HUMAN" 3 911.5553 0.79 76235 5186 2 911.553731 456.7849 Eukaryotic translation initiation factor 2 subunit 1 OS=Homo sapiens OX=9606 GN=EIF2S1 PE=1 SV=3 11 1491.4 - 839575 - - - -1.6664 - 1.32 0.19 - 95.9 9 2 0 -0.0015 8 0 0 0 1.83E+07 2.33E+07 - - - 0.8549 0.9998 221125_WJC_METTL3_EV_vs_WT_F06.05193.05193.2 0.00139 16-Oct K.TQELETTQK.H "sp|P52732|KIF11_HUMAN,tr|A0A7I2YQY4|A0A7I2YQY4_HUMAN,tr|A0A7I2V3A9|A0A7I2V3A9_HUMAN,tr|A0A7I2V3V3|A0A7I2V3V3_HUMAN" 4 1076.535 3.88 76240 5193 2 1076.535154 539.2748 Kinesin-like protein KIF11 OS=Homo sapiens OX=9606 GN=KIF11 PE=1 SV=2 4.53 1492.1 - 1.08E+07 - - - 0.1718 - 1.926 0.447 - 434.3 1 2 0 0.0002 9 0 0 0 2.61E+09 6.74E+08 - - - 4.2387 0.9952 221125_WJC_METTL3_EV_vs_WT_F06.05199.05199.2 0.673 12-Jul R.HSELLQK[136.11].V "sp|Q9Y2Q9|RT28_HUMAN,tr|E5RFT8|E5RFT8_HUMAN,tr|H7C5V3|H7C5V3_HUMAN" 3 861.48 1.13 76244 5199 2 861.47953 431.7473 "28S ribosomal protein S28, mitochondrial OS=Homo sapiens OX=9606 GN=MRPS28 PE=1 SV=1" 6.75 1492.7 - 9.75E+06 - - - -0.5073 - 1.367 0.151 - 199.9 1 2 0 -0.0004 7 0 0 0 1.76E+08 1.56E+08 - - - 1.1467 0.999 221125_WJC_METTL3_EV_vs_WT_F06.05201.05201.2 1.07 14-Sep R.NTEEEGLK.Y "sp|Q9NYF8|BCLF1_HUMAN,tr|E9PKI6|E9PKI6_HUMAN,tr|A0A1W2PQ43|A0A1W2PQ43_HUMAN,tr|E9PK91|E9PK91_HUMAN,tr|E9PK09|E9PK09_HUMAN,tr|E9PQN2|E9PQN2_HUMAN" 6 918.4294 2.14 76246 5201 2 918.428735 460.222 Bcl-2-associated transcription factor 1 OS=Homo sapiens OX=9606 GN=BCLAF1 PE=1 SV=2 4.25 1492.8 - 1.36E+07 - - - -0.7687 - 1.761 0.236 - 382.3 1 2 0 -0.0007 8 0 0 0 3.18E+08 1.49E+08 - - - 2.4905 0.9995 221125_WJC_METTL3_EV_vs_WT_F06.05212.05212.2 3.31 16-Oct K.TQELETTQK[136.11].H "sp|P52732|KIF11_HUMAN,tr|A0A7I2YQY4|A0A7I2YQY4_HUMAN,tr|A0A7I2V3A9|A0A7I2V3A9_HUMAN,tr|A0A7I2V3V3|A0A7I2V3V3_HUMAN" 4 1084.5492 3.82 76255 5212 2 1084.548284 543.2819 Kinesin-like protein KIF11 OS=Homo sapiens OX=9606 GN=KIF11 PE=1 SV=2 4.53 1493.9 - 2.90E+07 - - - -0.816 - 1.968 0.303 - 419.6 1 2 0 -0.0009 9 0 0 0 2.62E+09 6.84E+08 - - - 3.2373 0.9998 221125_WJC_METTL3_EV_vs_WT_F06.05214.05214.2 1.42E-05 16-Sep K.FAANPNQNK[136.11].N sp|Q15717|ELAV1_HUMAN 1 1010.5025 1.69 76257 5214 2 1010.502487 506.2585 ELAV-like protein 1 OS=Homo sapiens OX=9606 GN=ELAVL1 PE=1 SV=2 8.75 1494 - 6.88E+06 - - - -0.0059 - 1.783 0.494 - 236.7 1 2 0 0 9 0 0 0 1.68E+09 9.95E+08 - - - 4.3627 0.9601 221125_WJC_METTL3_EV_vs_WT_F06.05215.05215.2 3.6 12-Jun K.GFSNLKK.Q "sp|P11586|C1TC_HUMAN,tr|F5H2F4|F5H2F4_HUMAN,tr|V9GZ78|V9GZ78_HUMAN,tr|V9GYY3|V9GYY3_HUMAN,tr|A0A494C1T2|A0A494C1T2_HUMAN" 5 792.4494 1.77 76258 5215 2 792.449258 397.232 "C-1-tetrahydrofolate synthase, cytoplasmic OS=Homo sapiens OX=9606 GN=MTHFD1 PE=1 SV=4" 10 1494 - 6.78E+06 - - - -0.164 - 0.913 0.129 - 118.3 1 2 0 -0.0001 7 0 0 0 7.60E+07 4.29E+07 - - - -0.2946 0.998 221125_WJC_METTL3_EV_vs_WT_F06.05216.05216.2 0.128 12-Aug K.TQHEILR.Q sp|P49257|LMAN1_HUMAN 1 895.4876 1.34 76259 5216 2 895.486086 448.7511 Protein ERGIC-53 OS=Homo sapiens OX=9606 GN=LMAN1 PE=1 SV=2 6.41 1494.1 - 4.22E+06 - - - -1.6516 - 1.598 0.231 - 409.7 1 2 0 -0.0015 7 0 0 0 7.91E+07 5.90E+07 - - - 2.232 0.9871 221125_WJC_METTL3_EV_vs_WT_F06.05217.05217.2 0.000624 18-Aug R.QPC[160.03]ASQSSLK[136.11].D sp|Q92900|RENT1_HUMAN 1 1112.5376 3.1 76260 5217 2 1112.538461 557.2761 Regulator of nonsense transcripts 1 OS=Homo sapiens OX=9606 GN=UPF1 PE=1 SV=2 8.22 1494.1 - 1.46E+06 - - - 0.8117 - 1.484 0.059 - 163.9 1 2 0 0.0009 10 0 0 0 9.57E+07 3.09E+07 - - - 0.5783 0.9963 221125_WJC_METTL3_EV_vs_WT_F06.05223.05223.2 0.0223 24-Nov R.GEAAPGQGQAAVK[136.11].A sp|P17482|HXB9_HUMAN 1 1190.6135 1.29 76265 5223 2 1190.608334 596.314 Homeobox protein Hox-B9 OS=Homo sapiens OX=9606 GN=HOXB9 PE=1 SV=2 6 1494.8 - 519407 - - - -4.3389 - 1.952 0.375 - 338.9 1 2 0 -0.0052 13 0 0 0 1.21E+07 9.37E+06 - - - 3.5258 0.9995 221125_WJC_METTL3_EV_vs_WT_F06.05228.05228.2 0.00276 16-Aug R.AQQAC[160.03]IEAK[136.11].H "sp|Q9UNE7|CHIP_HUMAN,tr|H3BUD0|H3BUD0_HUMAN,tr|H3BS86|H3BS86_HUMAN,tr|H3BTA3|H3BTA3_HUMAN" 4 1025.5055 0.3 76268 5228 2 1025.507125 513.76 E3 ubiquitin-protein ligase CHIP OS=Homo sapiens OX=9606 GN=STUB1 PE=1 SV=2 6.04 1495.2 - 1.33E+07 - - - 1.5553 - 1.828 0.392 - 314.5 1 2 0 0.0016 9 0 0 0 3.66E+07 1.23E+08 - - - 3.681 0.9983 221125_WJC_METTL3_EV_vs_WT_F06.05235.05235.2 0.451 12-Jul K.SNLITHR.K sp|Q9BWE0|REPI1_HUMAN 1 839.4614 1.49 76275 5235 2 839.46085 420.738 Replication initiator 1 OS=Homo sapiens OX=9606 GN=REPIN1 PE=1 SV=1 9.49 1495.5 - 2.34E+06 - - - -0.5956 - 1.583 0.198 - 248.3 1 2 0 -0.0005 7 0 0 0 2.89E+07 1.94E+07 - - - 1.9587 0.9997 221125_WJC_METTL3_EV_vs_WT_F06.05240.05240.2 6.78E-05 18-Sep R.NPPGASTYNK.N "sp|Q9BUJ2|HNRL1_HUMAN,tr|A0A0A0MRA5|A0A0A0MRA5_HUMAN,tr|M0R3F1|M0R3F1_HUMAN,tr|B7Z4B8|B7Z4B8_HUMAN" 4 1047.4985 1.46 76278 5240 2 1047.497154 524.7565 Heterogeneous nuclear ribonucleoprotein U-like protein 1 OS=Homo sapiens OX=9606 GN=HNRNPUL1 PE=1 SV=2 8.59 1496.1 - 2.95E+07 - - - -1.3069 - 1.665 0.475 - 360.5 1 2 0 -0.0014 10 0 0 0 8.80E+08 6.03E+08 - - - 3.972 0.9989 221125_WJC_METTL3_EV_vs_WT_F06.05241.05241.2 0.0142 16-Aug R.TQEGSLSAR[166.11].W sp|P78527|PRKDC_HUMAN 1 957.4755 0.7 76279 5241 2 957.474477 479.745 DNA-dependent protein kinase catalytic subunit OS=Homo sapiens OX=9606 GN=PRKDC PE=1 SV=3 5.66 1496.1 - 1.02E+07 - - - -1.0611 - 1.771 0.236 - 283.5 1 2 0 -0.001 9 0 0 0 5.97E+07 8.55E+07 - - - 2.4373 0.97 221125_WJC_METTL3_EV_vs_WT_F06.05242.05242.2 4.4 16-Aug K.LK[136.11]AEGSEIR[166.11].L "sp|P07237|PDIA1_HUMAN,tr|A0A7P0TA97|A0A7P0TA97_HUMAN,tr|A0A7P0T8C0|A0A7P0T8C0_HUMAN,tr|H7BZ94|H7BZ94_HUMAN,tr|A0A7P0TA71|A0A7P0TA71_HUMAN,tr|I3L4M2|I3L4M2_HUMAN,tr|A0A7P0T9D6|A0A7P0T9D6_HUMAN,tr|H0Y3Z3|H0Y3Z3_HUMAN,tr|A0A7P0Z4S2|A0A7P0Z4S2_HUMAN,tr|I3NI03|I3NI03_HUMAN,tr|A0A7P0TA35|A0A7P0TA35_HUMAN,tr|A0A7P0TAX9|A0A7P0TAX9_HUMAN,tr|I3L514|I3L514_HUMAN,tr|A0A7P0Z476|A0A7P0Z476_HUMAN,tr|A0A7P0TBP8|A0A7P0TBP8_HUMAN,tr|A0A7P0TB26|A0A7P0TB26_HUMAN,tr|A0A7P0T9U6|A0A7P0T9U6_HUMAN,tr|I3L0S0|I3L0S0_HUMAN,tr|A0A7P0T8J3|A0A7P0T8J3_HUMAN,tr|A0A7P0Z4J0|A0A7P0Z4J0_HUMAN,tr|A0A7P0T9S9|A0A7P0T9S9_HUMAN,tr|A0A7P0T8X1|A0A7P0T8X1_HUMAN,tr|I3L3U6|I3L3U6_HUMAN" 23 1019.573 1.03 76280 5242 2 1019.572146 510.7938 Protein disulfide-isomerase OS=Homo sapiens OX=9606 GN=P4HB PE=1 SV=3 6.14 1496.1 - 8.24E+06 - - - -0.866 - 1.762 0.159 - 163.1 3 2 1 -0.0009 9 0 0 0 1.35E+08 1.31E+08 - - - 1.6407 0.9978 221125_WJC_METTL3_EV_vs_WT_F06.05243.05243.2 0.00115 16-Aug R.AQQEAPAVR[166.11].K sp|Q9NUL7|DDX28_HUMAN 1 978.5122 1.53 76281 5243 2 978.510627 490.2634 Probable ATP-dependent RNA helicase DDX28 OS=Homo sapiens OX=9606 GN=DDX28 PE=1 SV=2 6.05 1496.2 - 6.55E+06 - - - -1.6208 - 1.758 0.197 - 364.8 1 2 0 -0.0016 9 0 0 0 1.27E+08 8.30E+07 - - - 2.1277 0.9973 221125_WJC_METTL3_EV_vs_WT_F06.05245.05245.2 0.179 12-Jul K.SNLITHR[166.11].K sp|Q9BWE0|REPI1_HUMAN 1 849.4696 1.54 76283 5245 2 849.470679 425.7421 Replication initiator 1 OS=Homo sapiens OX=9606 GN=REPIN1 PE=1 SV=1 9.49 1496.3 - 2.12E+06 - - - 1.2467 - 1.515 0.205 - 369.2 1 2 0 0.0011 7 0 0 0 2.99E+07 1.94E+07 - - - 1.8711 0.9935 221125_WJC_METTL3_EV_vs_WT_F06.05246.05246.2 0.103 16-Sep K.ALVATPGKK.G "sp|P19338|NUCL_HUMAN,tr|A0A7I2V506|A0A7I2V506_HUMAN,tr|A0A7I2V699|A0A7I2V699_HUMAN,tr|A0A7I2V2U7|A0A7I2V2U7_HUMAN,tr|A0A7I2V3F3|A0A7I2V3F3_HUMAN,tr|A0A7I2V428|A0A7I2V428_HUMAN,tr|A0A7I2V349|A0A7I2V349_HUMAN,tr|H7BY16|H7BY16_HUMAN,tr|A0A7I2V5M5|A0A7I2V5M5_HUMAN,tr|A0A7I2V2S8|A0A7I2V2S8_HUMAN,tr|C9JLB1|C9JLB1_HUMAN" 11 883.5491 0.93 76284 5246 2 883.551446 442.7818 Nucleolin OS=Homo sapiens OX=9606 GN=NCL PE=1 SV=3 10 1496.3 - 2.10E+06 - - - 2.6529 - 1.664 0.183 - 313.6 1 2 0 0.0023 9 0 0 0 4.94E+07 5.33E+07 - - - 1.8651 0.9998 221125_WJC_METTL3_EV_vs_WT_F06.05248.05248.2 2.22E-05 14/24 R.SPAGGESATVAAK[136.11].G sp|Q147X3|NAA30_HUMAN 1 1152.5866 2.67 76286 5248 2 1152.584415 577.3006 N-alpha-acetyltransferase 30 OS=Homo sapiens OX=9606 GN=NAA30 PE=1 SV=1 5.72 1496.6 - 1.07E+06 - - - -1.9105 - 2.682 0.547 - 623 1 2 0 -0.0022 13 0 0 0 1.52E+07 5.71E+06 - - - 5.6125 0.9855 221125_WJC_METTL3_EV_vs_WT_F06.05255.05255.2 0.909 12-Jun R.EAQVNVR.M "sp|Q9Y2W1|TR150_HUMAN,tr|A0A3B3ITZ9|A0A3B3ITZ9_HUMAN" 2 814.4297 2.67 76291 5255 2 814.429146 408.2221 Thyroid hormone receptor-associated protein 3 OS=Homo sapiens OX=9606 GN=THRAP3 PE=1 SV=2 6.1 1497.5 - 1.42E+07 - - - -0.6999 - 1.24 0.094 - 260.7 1 2 0 -0.0006 7 0 0 0 6.67E+08 2.49E+08 - - - 0.4167 0.9986 221125_WJC_METTL3_EV_vs_WT_F06.05256.05256.2 0.147 16-Sep K.LQASNVTNK.N "sp|Q9UKM9|RALY_HUMAN,tr|Q5QPM0|Q5QPM0_HUMAN,tr|Q5QPM2|Q5QPM2_HUMAN,tr|Q5QPM1|Q5QPM1_HUMAN,tr|Q5QPL9|Q5QPL9_HUMAN" 5 973.5193 1.27 76292 5256 2 973.518619 487.7669 RNA-binding protein Raly OS=Homo sapiens OX=9606 GN=RALY PE=1 SV=1 8.75 1497.5 - 7.31E+06 - - - -0.6574 - 1.546 0.248 - 241.9 1 2 0 -0.0006 9 0 0 0 3.94E+08 3.10E+08 - - - 2.1329 0.9879 221125_WJC_METTL3_EV_vs_WT_F06.05258.05258.2 0.000103 20-Sep R.R[166.11]AEQDSTTVAA.F "sp|Q86U44|MTA70_HUMAN,tr|F5H6D8|F5H6D8_HUMAN,tr|H0YFV6|H0YFV6_HUMAN,tr|B4DTN4|B4DTN4_HUMAN" 4 1157.5552 0.02 76294 5258 2 1157.554765 579.7849 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 4.37 1497.6 - 5.30E+06 - - - -0.3758 - 1.77 0.472 - 311.9 1 1 0 -0.0004 11 0 0 0 2.20E+07 1.01E+09 - - - 4.0717 0.9973 221125_WJC_METTL3_EV_vs_WT_F06.05259.05259.2 0.509 16-Sep R.TQEGSLSAR.W sp|P78527|PRKDC_HUMAN 1 947.4672 0.69 76295 5259 2 947.467496 474.7409 DNA-dependent protein kinase catalytic subunit OS=Homo sapiens OX=9606 GN=PRKDC PE=1 SV=3 5.66 1497.7 - 4.83E+06 - - - 0.2881 - 1.639 0.151 - 416 1 2 0 0.0003 9 0 0 0 5.94E+07 8.56E+07 - - - 1.5856 0.9979 221125_WJC_METTL3_EV_vs_WT_F06.05261.05261.3 0.322 Dec-40 R.ITAASQEHGLK.Y "sp|Q9BYC9|RM20_HUMAN,tr|I3L2X1|I3L2X1_HUMAN" 2 1153.6091 0.47 76297 5261 3 1153.608627 385.5437 "39S ribosomal protein L20, mitochondrial OS=Homo sapiens OX=9606 GN=MRPL20 PE=1 SV=1" 6.75 1497.7 - 2.57E+06 - - - -0.4421 - 2.1 0.193 - 134.1 1 2 0 -0.0005 11 0 0 0 1.87E+07 3.99E+07 - - - 2.7993 0.9999 221125_WJC_METTL3_EV_vs_WT_F06.05263.05263.2 0.00318 16-Oct R.ADEDC[160.03]VDDR.A "sp|O15417|TNC18_HUMAN,tr|H9KVB4|H9KVB4_HUMAN,tr|H7C3U5|H7C3U5_HUMAN" 3 1093.3982 0.3 76299 5263 2 1093.39815 547.7064 Trinucleotide repeat-containing gene 18 protein OS=Homo sapiens OX=9606 GN=TNRC18 PE=1 SV=3 3.71 1497.9 - 1.90E+06 - - - -0.0613 - 2.315 0.471 - 517.5 1 2 0 -0.0001 9 0 0 0 1.33E+07 4.41E+07 - - - 4.9482 0.9998 221125_WJC_METTL3_EV_vs_WT_F06.05264.05264.2 8.21E-05 20-Nov R.ALTQTGGPHVK[136.11].A "sp|P21333|FLNA_HUMAN,tr|Q60FE5|Q60FE5_HUMAN" 2 1115.6179 1.16 76300 5264 2 1115.617641 558.8162 Filamin-A OS=Homo sapiens OX=9606 GN=FLNA PE=1 SV=4 8.8 1498.1 - 1.77E+06 - - - -0.1936 - 2.039 0.432 - 410 1 2 0 -0.0002 11 0 0 0 3.00E+07 2.59E+07 - - - 4.1591 0.9994 221125_WJC_METTL3_EV_vs_WT_F06.05268.05268.2 0.011 12-Jul R.NSMFHNR.H "sp|Q99873|ANM1_HUMAN,tr|E9PQ98|E9PQ98_HUMAN,tr|E9PKG1|E9PKG1_HUMAN,tr|E9PMZ2|E9PMZ2_HUMAN,tr|E9PNR9|E9PNR9_HUMAN,tr|H0YDE4|H0YDE4_HUMAN,tr|E9PMW9|E9PMW9_HUMAN,tr|E9PIX6|E9PIX6_HUMAN" 8 904.3974 1.98 76302 5268 2 904.396515 453.206 Protein arginine N-methyltransferase 1 OS=Homo sapiens OX=9606 GN=PRMT1 PE=1 SV=3 9.76 1498.5 - 2.63E+07 - - - -0.9454 - 1.59 0.338 - 321.5 1 2 0 -0.0009 7 0 0 0 2.65E+08 1.34E+08 - - - 3.0066 0.9822 221125_WJC_METTL3_EV_vs_WT_F06.05270.05270.2 1.22 12-Jun R.EAQVNVR[166.11].M "sp|Q9Y2W1|TR150_HUMAN,tr|A0A3B3ITZ9|A0A3B3ITZ9_HUMAN" 2 824.438 2.67 76304 5270 2 824.436905 413.2263 Thyroid hormone receptor-associated protein 3 OS=Homo sapiens OX=9606 GN=THRAP3 PE=1 SV=2 6.1 1498.6 - 1.69E+07 - - - -1.3112 - 1.216 0.107 - 262.6 1 2 0 -0.0011 7 0 0 0 6.67E+08 2.49E+08 - - - 0.4506 0.9998 221125_WJC_METTL3_EV_vs_WT_F06.05271.05271.2 0.00425 12-Aug R.NSMFHNR[166.11].H "sp|Q99873|ANM1_HUMAN,tr|E9PQ98|E9PQ98_HUMAN,tr|E9PKG1|E9PKG1_HUMAN,tr|E9PMZ2|E9PMZ2_HUMAN,tr|E9PNR9|E9PNR9_HUMAN,tr|H0YDE4|H0YDE4_HUMAN,tr|E9PMW9|E9PMW9_HUMAN,tr|E9PIX6|E9PIX6_HUMAN" 8 914.4056 1.98 76305 5271 2 914.4049 458.2101 Protein arginine N-methyltransferase 1 OS=Homo sapiens OX=9606 GN=PRMT1 PE=1 SV=3 9.76 1498.6 - 1.42E+07 - - - -0.8093 - 1.636 0.524 - 494 1 2 0 -0.0007 7 0 0 0 2.65E+08 1.34E+08 - - - 4.4708 0.9993 221125_WJC_METTL3_EV_vs_WT_F06.05272.05272.2 0.0171 14-Aug R.TVHSVLNR[166.11].S "sp|Q86SR1|GLT10_HUMAN,sp|Q10472|GALT1_HUMAN,tr|F2Z2M7|F2Z2M7_HUMAN,tr|K7EJV8|K7EJV8_HUMAN" 4 934.5224 1.23 76306 5272 2 934.521914 468.2685 Polypeptide N-acetylgalactosaminyltransferase 10 OS=Homo sapiens OX=9606 GN=GALNT10 PE=1 SV=2 9.44 1498.6 - 4.85E+06 - - - -0.5029 - 1.313 0.386 - 226.7 1 2 0 -0.0005 8 0 0 0 5.59E+07 4.56E+07 - - - 2.7131 0.9946 221125_WJC_METTL3_EV_vs_WT_F06.05274.05274.2 0.401 12-Aug R.HQELLQK.K sp|Q9NQS7|INCE_HUMAN 1 894.4923 0.73 76308 5274 2 894.492348 448.2534 Inner centromere protein OS=Homo sapiens OX=9606 GN=INCENP PE=1 SV=3 6.75 1498.7 - 3.01E+06 - - - 0.0358 - 1.247 0.177 - 230.4 1 2 0 0 7 0 0 0 7.24E+07 9.90E+07 - - - 1.0477 0.9997 221125_WJC_METTL3_EV_vs_WT_F06.05276.05276.2 0.000451 20-Dec R.ALTQTGGPHVK.A "sp|P21333|FLNA_HUMAN,tr|Q60FE5|Q60FE5_HUMAN" 2 1107.6037 1.23 76310 5276 2 1107.601624 554.8091 Filamin-A OS=Homo sapiens OX=9606 GN=FLNA PE=1 SV=4 8.8 1498.9 - 2.13E+06 - - - -1.8355 - 2.276 0.45 - 509.1 1 2 0 -0.002 11 0 0 0 3.20E+07 2.59E+07 - - - 4.5889 0.9996 221125_WJC_METTL3_EV_vs_WT_F06.05283.05283.2 0.0103 14-Sep K.SQQALVQK[136.11].R "sp|P24539|AT5F1_HUMAN,tr|Q5QNZ2|Q5QNZ2_HUMAN" 2 908.5171 1.07 76315 5283 2 908.515547 455.2658 "ATP synthase F(0) complex subunit B1, mitochondrial OS=Homo sapiens OX=9606 GN=ATP5PB PE=1 SV=2" 8.47 1499.7 - 1.05E+07 - - - -1.6885 - 1.807 0.418 - 389 1 2 0 -0.0015 8 0 0 0 2.56E+08 2.39E+08 - - - 3.9123 0.999 221125_WJC_METTL3_EV_vs_WT_F06.05284.05284.2 0.0592 14-Jul K.QGTEIDGR.S "sp|P19338|NUCL_HUMAN,tr|A0A7I2V506|A0A7I2V506_HUMAN,tr|A0A7I2V2U7|A0A7I2V2U7_HUMAN,tr|A0A7I2V3F3|A0A7I2V3F3_HUMAN,tr|A0A7I2V428|A0A7I2V428_HUMAN,tr|A0A7I2V349|A0A7I2V349_HUMAN,tr|H7BY16|H7BY16_HUMAN,tr|A0A7I2V5M5|A0A7I2V5M5_HUMAN,tr|C9JLB1|C9JLB1_HUMAN" 9 874.4145 0.75 76316 5284 2 874.41385 438.2145 Nucleolin OS=Homo sapiens OX=9606 GN=NCL PE=1 SV=3 4.37 1499.7 - 4.37E+06 - - - -0.6965 - 1.371 0.33 - 256.3 1 2 0 -0.0006 8 0 0 0 5.46E+07 7.30E+07 - - - 2.4298 0.893 221125_WJC_METTL3_EV_vs_WT_F06.05285.05285.2 0.046 18-Aug R.EAATAVEQEK[136.11].E sp|O95816|BAG2_HUMAN 1 1082.5335 3.44 76317 5285 2 1083.540135 542.274 BAG family molecular chaperone regulator 2 OS=Homo sapiens OX=9606 GN=BAG2 PE=1 SV=1 4.25 1499.7 - 1.03E+07 - - - 929.8705 - 1.707 0.349 - 194.2 1 2 0 1.0066 10 0 0 0 2.23E+09 6.46E+08 - - - 2.7953 0.9913 221125_WJC_METTL3_EV_vs_WT_F06.05286.05286.2 1.66 12-Jul R.LQAEIKR.L sp|P15924|DESP_HUMAN 1 856.5131 40.63 76318 5286 2 856.511989 429.2638 Desmoplakin OS=Homo sapiens OX=9606 GN=DSP PE=1 SV=3 8.75 1499.8 - 3.81E+06 - - - -1.2399 - 1.464 0.09 - 174.7 1 2 0 -0.0011 7 0 0 0 4.12E+07 1.01E+06 - - - 0.9132 0.9997 221125_WJC_METTL3_EV_vs_WT_F06.05288.05288.2 0.842 22-Nov K.LEGAGSSSAPER[166.11].N sp|P57086|SCND1_HUMAN 1 1169.5552 12.27 76320 5288 2 1169.555911 585.7849 SCAN domain-containing protein 1 OS=Homo sapiens OX=9606 GN=SCAND1 PE=1 SV=1 4.53 1499.9 - 2.60E+06 - - - 0.6079 - 2.366 0.346 - 437.2 1 2 0 0.0007 12 0 0 0 3.58E+08 2.92E+07 - - - 3.8623 0.9998 221125_WJC_METTL3_EV_vs_WT_F06.05294.05294.2 0.000854 12-Nov K.HTLTQIK[136.11].D sp|P40227|TCPZ_HUMAN 1 847.5007 0.48 76324 5294 2 847.499916 424.7576 T-complex protein 1 subunit zeta OS=Homo sapiens OX=9606 GN=CCT6A PE=1 SV=3 8.76 1500.6 - 2.42E+07 - - - -0.9274 - 1.98 0.388 - 361.9 1 2 0 -0.0008 7 0 0 0 1.28E+09 2.66E+09 - - - 4.071 0.949 221125_WJC_METTL3_EV_vs_WT_F06.05295.05295.2 0.279 14-Aug R.LQEKEELR.E "sp|P20700|LMNB1_HUMAN,sp|Q03252|LMNB2_HUMAN,tr|A0A0D9SFY5|A0A0D9SFY5_HUMAN,tr|E9PBF6|E9PBF6_HUMAN,tr|A0A0D9SFE5|A0A0D9SFE5_HUMAN" 5 1043.5611 1.17 76325 5295 2 1043.560071 522.7878 Lamin-B1 OS=Homo sapiens OX=9606 GN=LMNB1 PE=1 SV=2 4.79 1500.7 - 9.86E+06 - - - -1.009 - 1.534 0.127 - 275.7 1 2 1 -0.0011 8 0 0 0 1.21E+08 1.04E+08 - - - 1.2692 0.9995 221125_WJC_METTL3_EV_vs_WT_F06.05296.05296.2 0.012 12-Oct K.HTLTQIK.D sp|P40227|TCPZ_HUMAN 1 839.4865 0.48 76326 5296 2 839.48562 420.7505 T-complex protein 1 subunit zeta OS=Homo sapiens OX=9606 GN=CCT6A PE=1 SV=3 8.76 1500.7 - 7.54E+06 - - - -1.0506 - 1.672 0.337 - 303.3 1 2 0 -0.0009 7 0 0 0 1.28E+09 2.66E+09 - - - 3.1585 0.9764 221125_WJC_METTL3_EV_vs_WT_F06.05299.05299.2 6.63 12-Jul R.HLSEQLR[166.11].H "sp|Q68BL7|OLM2A_HUMAN,sp|Q676U5|A16L1_HUMAN,tr|E7EVC7|E7EVC7_HUMAN,tr|C9JAY7|C9JAY7_HUMAN,tr|Q5JTM7|Q5JTM7_HUMAN,tr|F8WAF9|F8WAF9_HUMAN,tr|C9J1B2|C9J1B2_HUMAN,tr|C9JK97|C9JK97_HUMAN" 8 891.4802 1.36 76328 5299 2 891.480626 446.7474 Olfactomedin-like protein 2A OS=Homo sapiens OX=9606 GN=OLFML2A PE=2 SV=1 6.75 1500.9 - 6.73E+06 - - - 0.4947 - 1.225 0.057 - 182.8 1 2 0 0.0004 7 0 0 0 8.14E+08 6.00E+08 - - - 0.1049 0.9997 221125_WJC_METTL3_EV_vs_WT_F06.05304.05304.2 0.00273 18-Nov R.EGQEDQGLTK[136.11].D "sp|O95758|PTBP3_HUMAN,sp|P26599|PTBP1_HUMAN,tr|A0A0U1RRM4|A0A0U1RRM4_HUMAN,tr|A6NLN1|A6NLN1_HUMAN,tr|A0A0D9SF20|A0A0D9SF20_HUMAN,tr|A0A7I2V621|A0A7I2V621_HUMAN,tr|A0A087WUW5|A0A087WUW5_HUMAN" 7 1111.5237 15.2 76332 5304 2 1111.523144 556.7691 Polypyrimidine tract-binding protein 3 OS=Homo sapiens OX=9606 GN=PTBP3 PE=1 SV=2 4.14 1501.4 - 2.07E+06 - - - -0.484 - 1.953 0.367 - 439.3 1 2 0 -0.0005 10 0 0 0 5.93E+10 3.90E+09 - - - 3.6199 0.9998 221125_WJC_METTL3_EV_vs_WT_F06.05312.05312.2 2.19E-05 18-Dec R.EGQEDQGLTK.D "sp|O95758|PTBP3_HUMAN,sp|P26599|PTBP1_HUMAN,tr|A0A0U1RRM4|A0A0U1RRM4_HUMAN,tr|A6NLN1|A6NLN1_HUMAN,tr|A0A0D9SF20|A0A0D9SF20_HUMAN,tr|A0A7I2V621|A0A7I2V621_HUMAN,tr|A0A087WUW5|A0A087WUW5_HUMAN" 7 1103.5095 15.29 76338 5312 2 1103.508483 552.762 Polypyrimidine tract-binding protein 3 OS=Homo sapiens OX=9606 GN=PTBP3 PE=1 SV=2 4.14 1502.3 - 1.08E+07 - - - -0.9053 - 2.221 0.386 - 698.4 1 2 0 -0.001 10 0 0 0 5.95E+10 3.89E+09 - - - 4.119 0.9952 221125_WJC_METTL3_EV_vs_WT_F06.05316.05316.2 0.14 12-Jul K.FNDPHVK[136.11].T sp|O75643|U520_HUMAN 1 863.4381 0.41 76342 5316 2 863.43614 432.7263 U5 small nuclear ribonucleoprotein 200 kDa helicase OS=Homo sapiens OX=9606 GN=SNRNP200 PE=1 SV=2 6.74 1502.4 - 2.99E+06 - - - -2.2723 - 1.49 0.211 - 135.5 1 2 0 -0.002 7 0 0 0 9.26E+07 2.26E+08 - - - 1.8624 0.9984 221125_WJC_METTL3_EV_vs_WT_F06.05324.05324.2 1.68 18-Nov K.KLIAAQTGTR.W sp|Q9BZL1|UBL5_HUMAN 1 1057.6244 1.76 76348 5324 2 1057.62265 529.8195 Ubiquitin-like protein 5 OS=Homo sapiens OX=9606 GN=UBL5 PE=1 SV=1 11 1503.2 - 4.84E+06 - - - -1.648 - 2.253 0.149 - 449.2 1 2 0 -0.0017 10 0 0 0 5.42E+07 3.09E+07 - - - 2.4082 0.9979 221125_WJC_METTL3_EV_vs_WT_F06.05325.05325.2 0.00128 18-Dec K.LK[136.11]ETAENSLK[136.11].K "sp|Q92598|HS105_HUMAN,tr|A0A0A0MSM0|A0A0A0MSM0_HUMAN" 2 1147.642 0.09 76349 5325 2 1147.640762 574.8283 Heat shock protein 105 kDa OS=Homo sapiens OX=9606 GN=HSPH1 PE=1 SV=1 6.14 1503.3 - 3.86E+06 - - - -1.0378 - 2.439 0.4 - 304.2 1 2 1 -0.0012 10 0 0 0 6.61E+06 7.77E+07 - - - 4.4837 0.9994 221125_WJC_METTL3_EV_vs_WT_F06.05328.05328.2 0.000386 18-Sep K.GGDIEAQSER[166.11].T "sp|Q8IWZ3|ANKH1_HUMAN,tr|E9PDP5|E9PDP5_HUMAN,tr|H3BLS9|H3BLS9_HUMAN,tr|H7C2F5|H7C2F5_HUMAN" 4 1070.4868 1.45 76352 5328 2 1070.486839 536.2507 Ankyrin repeat and KH domain-containing protein 1 OS=Homo sapiens OX=9606 GN=ANKHD1 PE=1 SV=1 4.14 1503.4 - 3.61E+06 - - - 0.0495 - 1.786 0.286 - 278.7 1 2 0 0.0001 10 0 0 0 3.16E+08 2.19E+08 - - - 2.7723 0.9986 221125_WJC_METTL3_EV_vs_WT_F06.05329.05329.2 0.274 18-Sep K.K[136.11]LIAAQTGTR[166.11].W sp|Q9BZL1|UBL5_HUMAN 1 1075.6469 1.76 76353 5329 2 1075.645885 538.8307 Ubiquitin-like protein 5 OS=Homo sapiens OX=9606 GN=UBL5 PE=1 SV=1 11 1503.4 - 3.40E+06 - - - -0.9092 - 1.886 0.192 - 239.2 1 2 0 -0.001 10 0 0 0 5.42E+07 3.09E+07 - - - 2.2298 0.9999 221125_WJC_METTL3_EV_vs_WT_F06.05336.05336.2 6.77E-05 16-Oct K.EDAANNYAR[166.11].G "sp|Q9NY65|TBA8_HUMAN,sp|P0DPH7|TBA3C_HUMAN,sp|Q71U36|TBA1A_HUMAN,sp|P0DPH8|TBA3D_HUMAN,sp|A6NHL2|TBAL3_HUMAN,sp|P68366|TBA4A_HUMAN,sp|P68363|TBA1B_HUMAN,sp|Q9BQE3|TBA1C_HUMAN,tr|C9JJQ8|C9JJQ8_HUMAN,tr|F8VS66|F8VS66_HUMAN,tr|F8VWV9|F8VWV9_HUMAN,tr|F8VRZ4|F8VRZ4_HUMAN,tr|F8VVB9|F8VVB9_HUMAN,tr|C9JQ00|C9JQ00_HUMAN,tr|C9JEV8|C9JEV8_HUMAN,tr|A0A7P0TA31|A0A7P0TA31_HUMAN,tr|A0A1W2PQM2|A0A1W2PQM2_HUMAN,tr|F5H5D3|F5H5D3_HUMAN,tr|C9J2C0|C9J2C0_HUMAN,tr|C9K0S6|C9K0S6_HUMAN,tr|C9JDL2|C9JDL2_HUMAN,tr|F8VQQ4|F8VQQ4_HUMAN,tr|F8VX09|F8VX09_HUMAN,tr|A0A7P0T945|A0A7P0T945_HUMAN" 24 1032.45 0.62 76358 5336 2 1032.448969 517.2323 Tubulin alpha-8 chain OS=Homo sapiens OX=9606 GN=TUBA8 PE=1 SV=1 4.37 1504.2 - 2.02E+07 - - - -1.0054 - 2.26 0.515 - 641.2 1 2 0 -0.001 9 0 0 0 1.47E+09 2.36E+09 - - - 5.2034 0.9998 221125_WJC_METTL3_EV_vs_WT_F06.05337.05337.2 6.85E-05 18-Oct K.GGDIEAQSER.T "sp|Q8IWZ3|ANKH1_HUMAN,tr|E9PDP5|E9PDP5_HUMAN,tr|H3BLS9|H3BLS9_HUMAN,tr|H7C2F5|H7C2F5_HUMAN" 4 1060.4785 1.45 76359 5337 2 1060.479609 531.2465 Ankyrin repeat and KH domain-containing protein 1 OS=Homo sapiens OX=9606 GN=ANKHD1 PE=1 SV=1 4.14 1504.2 - 1.55E+07 - - - 1.0307 - 1.963 0.517 - 462.6 1 2 0 0.0011 10 0 0 0 3.16E+08 2.19E+08 - - - 4.7419 0.8595 221125_WJC_METTL3_EV_vs_WT_F06.05338.05338.2 1.53 12-May K.FNDPHVK.T sp|O75643|U520_HUMAN 1 855.4239 0.41 76360 5338 2 855.422076 428.7192 U5 small nuclear ribonucleoprotein 200 kDa helicase OS=Homo sapiens OX=9606 GN=SNRNP200 PE=1 SV=2 6.74 1504.2 - 1.02E+07 - - - -2.1346 - 0.969 0.062 - 55.7 1 2 0 -0.0018 7 0 0 0 9.26E+07 2.25E+08 - - - -0.6014 0.9997 221125_WJC_METTL3_EV_vs_WT_F06.05340.05340.2 0.000135 16-Sep R.YEATSVQQK.V "sp|Q5JTV8|TOIP1_HUMAN,tr|H0YD16|H0YD16_HUMAN,tr|J3KN66|J3KN66_HUMAN,tr|A0A0A0MSK5|A0A0A0MSK5_HUMAN" 4 1052.5138 0.85 76362 5340 2 1052.514563 527.2642 Torsin-1A-interacting protein 1 OS=Homo sapiens OX=9606 GN=TOR1AIP1 PE=1 SV=2 6 1504.4 - 4.62E+06 - - - 0.6879 - 1.712 0.429 - 209.1 1 2 0 0.0007 9 0 0 0 3.34E+07 3.93E+07 - - - 3.7649 0.9882 221125_WJC_METTL3_EV_vs_WT_F06.05341.05341.2 0.0864 16-Aug K.LAVGDNNSK.W "sp|P46940|IQGA1_HUMAN,tr|H0YLE8|H0YLE8_HUMAN,tr|A0A0J9YXZ5|A0A0J9YXZ5_HUMAN" 3 916.4614 1.84 76363 5341 2 916.458156 459.238 Ras GTPase-activating-like protein IQGAP1 OS=Homo sapiens OX=9606 GN=IQGAP1 PE=1 SV=1 5.84 1504.4 - 2.07E+06 - - - -3.5506 - 1.392 0.256 - 148.8 1 2 0 -0.0033 9 0 0 0 4.78E+07 2.60E+07 - - - 1.8876 0.9998 221125_WJC_METTL3_EV_vs_WT_F06.05342.05342.2 0.00117 16-Sep K.C[160.03]IAC[160.03]QC[160.03]PSK.Q sp|P49792|RBP2_HUMAN 1 1122.462 0.56 76364 5342 2 1122.461404 562.2383 E3 SUMO-protein ligase RanBP2 OS=Homo sapiens OX=9606 GN=RANBP2 PE=1 SV=2 7.96 1504.5 - 1.87E+06 - - - -0.5497 - 1.686 0.445 - 249.8 1 2 0 -0.0006 9 0 0 0 1.42E+07 2.52E+07 - - - 3.8388 0.9995 221125_WJC_METTL3_EV_vs_WT_F06.05344.05344.2 3.31E-05 12-Oct K.SHAFSHV.- sp|Q9NR12|PDLI7_HUMAN 1 783.3664 - 76366 5344 2 783.364265 392.6905 PDZ and LIM domain protein 7 OS=Homo sapiens OX=9606 GN=PDLIM7 PE=1 SV=1 6.66 1504.7 - 1.12E+06 - - - -2.7088 - 1.847 0.512 - 370.3 1 2 0 -0.0021 7 0 0 0 - - - - - 4.7661 0.9879 221125_WJC_METTL3_EV_vs_WT_F06.05349.05349.2 2.82E-05 14-Sep V.VNDAGR[166.11]PK[136.11].V "sp|P11142|HSP7C_HUMAN,tr|E9PQQ4|E9PQQ4_HUMAN,tr|E9PNE6|E9PNE6_HUMAN,tr|E9PKE3|E9PKE3_HUMAN,tr|E9PN89|E9PN89_HUMAN,tr|E9PLF4|E9PLF4_HUMAN,tr|E9PK54|E9PK54_HUMAN,tr|E9PN25|E9PN25_HUMAN,tr|E9PPY6|E9PPY6_HUMAN,tr|E9PQK7|E9PQK7_HUMAN" 10 873.4787 0.19 76368 5349 2 873.477616 437.7466 Heat shock cognate 71 kDa protein OS=Homo sapiens OX=9606 GN=HSPA8 PE=1 SV=1 8.72 1505.3 - 1.38E+07 - - - -1.2811 - 1.91 0.476 - 235.4 1 1 0 -0.0011 8 0 0 0 3.61E+07 1.95E+08 - - - 4.508 0.9943 221125_WJC_METTL3_EV_vs_WT_F06.05350.05350.2 0.00745 16-Jul R.HTGQIGGLK[136.11].L "sp|Q9BW92|SYTM_HUMAN,tr|F6S7Q7|F6S7Q7_HUMAN,tr|U3KQG0|U3KQG0_HUMAN" 3 917.5174 0.58 76369 5350 2 917.513939 459.766 "Threonine--tRNA ligase, mitochondrial OS=Homo sapiens OX=9606 GN=TARS2 PE=1 SV=1" 8.76 1505.3 - 4.07E+06 - - - -3.7885 - 1.519 0.329 - 102.9 1 2 0 -0.0035 9 0 0 0 2.69E+07 4.63E+07 - - - 2.6793 0.9935 221125_WJC_METTL3_EV_vs_WT_F06.05352.05352.2 0.179 18-Aug K.ALSSPGQPSK.C "sp|Q99717|SMAD5_HUMAN,tr|D6RBB4|D6RBB4_HUMAN,tr|D6R9D4|D6R9D4_HUMAN,tr|D6RIZ9|D6RIZ9_HUMAN" 4 970.5084 1.7 76371 5352 2 970.507169 486.2615 Mothers against decapentaplegic homolog 5 OS=Homo sapiens OX=9606 GN=SMAD5 PE=1 SV=1 8.8 1505.4 - 1.48E+07 - - - -1.2272 - 1.222 0.205 - 207.2 1 2 0 -0.0012 10 0 0 0 5.16E+08 3.04E+08 - - - 1.1144 0.9998 221125_WJC_METTL3_EV_vs_WT_F06.05355.05355.2 0.00475 22-Dec R.GPPASSPAPAPK.F "sp|Q15942|ZYX_HUMAN,tr|H7C3D3|H7C3D3_HUMAN,tr|H0Y2Y8|H0Y2Y8_HUMAN" 3 1075.5662 4.35 76374 5355 2 1075.566537 538.7904 Zyxin OS=Homo sapiens OX=9606 GN=ZYX PE=1 SV=1 8.75 1505.6 - 2.77E+06 - - - 0.305 - 2.241 0.4 - 319.6 1 2 0 0.0003 12 0 0 0 2.94E+08 6.76E+07 - - - 4.1184 0.9996 221125_WJC_METTL3_EV_vs_WT_F06.05359.05359.2 0.00273 14-Jul R.EAVTHIGR.V "sp|P06730|IF4E_HUMAN,tr|D6RBW1|D6RBW1_HUMAN" 2 881.4719 1.24 76377 5359 2 881.471008 441.7432 Eukaryotic translation initiation factor 4E OS=Homo sapiens OX=9606 GN=EIF4E PE=1 SV=2 6.85 1506.1 - 3.65E+07 - - - -1.029 - 1.639 0.398 - 351.7 1 2 0 -0.0009 8 0 0 0 8.20E+08 6.63E+08 - - - 3.4705 0.9962 221125_WJC_METTL3_EV_vs_WT_F06.05361.05361.2 0.12 12-Jul R.SVPHLQK.V "sp|P07355|ANXA2_HUMAN,sp|A6NMY6|AXA2L_HUMAN,tr|H0YL33|H0YL33_HUMAN,tr|H0YMU9|H0YMU9_HUMAN,tr|H0YM50|H0YM50_HUMAN,tr|H0YMD0|H0YMD0_HUMAN,tr|H0YMW4|H0YMW4_HUMAN,tr|H0YN42|H0YN42_HUMAN,tr|H0YN28|H0YN28_HUMAN,tr|H0YNP5|H0YNP5_HUMAN" 10 807.4603 6.74 76378 5361 2 807.459166 404.7374 Annexin A2 OS=Homo sapiens OX=9606 GN=ANXA2 PE=1 SV=2 8.49 1506.3 - 1.76E+07 - - - -1.3883 - 1.188 0.271 - 162.7 1 2 0 -0.0011 7 0 0 0 2.70E+08 4.00E+07 - - - 1.5881 0.8416 221125_WJC_METTL3_EV_vs_WT_F06.05366.05366.2 0.144 12-Jul G.QALSSC[160.03]R.N tr|G5EA40|G5EA40_HUMAN 1 820.3861 3.09 76381 5366 2 820.384872 411.2003 Electron transfer flavoprotein beta subunit lysine methyltransferase OS=Homo sapiens OX=9606 GN=ETFBKMT PE=4 SV=1 8.25 1506.8 - 9.25E+06 - - - -1.5407 - 1.349 0.246 - 253.4 1 1 0 -0.0013 7 0 0 0 1.33E+08 4.30E+07 - - - 1.8061 0.9835 221125_WJC_METTL3_EV_vs_WT_F06.05371.05371.3 0.000396 Nov-40 R.PGPYDRPGTAR.R sp|P52597|HNRPF_HUMAN 1 1185.5891 0.8 76384 5371 3 1185.587884 396.2036 Heterogeneous nuclear ribonucleoprotein F OS=Homo sapiens OX=9606 GN=HNRNPF PE=1 SV=3 9.17 1507.3 - 4.73E+06 - - - -1.0003 - 1.983 0.384 - 221.6 1 1 0 -0.0012 11 0 0 0 1.18E+08 1.47E+08 - - - 4.7658 0.9983 221125_WJC_METTL3_EV_vs_WT_F06.05373.05373.2 0.0411 14-Jul K.IEYAKPTR.L "sp|P14866|HNRPL_HUMAN,tr|B4DVF8|B4DVF8_HUMAN,tr|M0R1W6|M0R1W6_HUMAN,tr|A0A3B3ITJ4|A0A3B3ITJ4_HUMAN,tr|M0QXS5|M0QXS5_HUMAN" 5 976.5342 1.27 76385 5373 2 976.532299 489.2744 Heterogeneous nuclear ribonucleoprotein L OS=Homo sapiens OX=9606 GN=HNRNPL PE=1 SV=2 8.59 1507.4 - 1.42E+07 - - - -1.9272 - 1.508 0.309 - 219.3 1 2 0 -0.0019 8 0 0 0 3.07E+08 2.43E+08 - - - 2.5616 0.9983 221125_WJC_METTL3_EV_vs_WT_F06.05379.05379.2 0.00138 14/18 R.ATATHTDVLK.D "sp|Q9H6R4|NOL6_HUMAN,tr|A0A0A0MRW6|A0A0A0MRW6_HUMAN" 2 1055.5611 1.26 76388 5379 2 1055.555972 528.7878 Nucleolar protein 6 OS=Homo sapiens OX=9606 GN=NOL6 PE=1 SV=2 6.79 1508.1 - 3.67E+06 - - - -4.8808 - 2.585 0.492 - 710.7 1 2 0 -0.0052 10 0 0 0 5.25E+07 4.18E+07 - - - 5.3243 0.9998 221125_WJC_METTL3_EV_vs_WT_F06.05382.05382.3 9.96E-05 16/36 R.ER[166.11]PPEEVAAR[166.11].L "sp|Q16891|MIC60_HUMAN,tr|B9A067|B9A067_HUMAN,tr|A0A087WYS0|A0A087WYS0_HUMAN,tr|C9J406|C9J406_HUMAN" 4 1172.6053 1.49 76389 5382 3 1172.603 391.8757 MICOS complex subunit MIC60 OS=Homo sapiens OX=9606 GN=IMMT PE=1 SV=1 4.79 1508.5 - 4.95E+06 - - - -1.941 - 2.174 0.392 - 394.4 1 2 0 -0.0023 10 0 0 0 5.42E+08 3.64E+08 - - - 5.1777 0.9992 221125_WJC_METTL3_EV_vs_WT_F06.05384.05384.2 0.189 18-Oct K.ALQSGPPQSR.R sp|O00425|IF2B3_HUMAN 1 1039.5411 1.52 76391 5384 2 1039.542171 520.7778 Insulin-like growth factor 2 mRNA-binding protein 3 OS=Homo sapiens OX=9606 GN=IGF2BP3 PE=1 SV=2 9.79 1508.6 - 5.37E+06 - - - 1.0716 - 2.035 0.251 - 555 1 2 0 0.0011 10 0 0 0 3.09E+08 2.04E+08 - - - 2.8777 0.9998 221125_WJC_METTL3_EV_vs_WT_F06.05386.05386.2 2.08E-05 16-Aug K.EDAANNYAR.G "sp|Q9NY65|TBA8_HUMAN,sp|P0DPH7|TBA3C_HUMAN,sp|Q71U36|TBA1A_HUMAN,sp|P0DPH8|TBA3D_HUMAN,sp|A6NHL2|TBAL3_HUMAN,sp|P68366|TBA4A_HUMAN,sp|P68363|TBA1B_HUMAN,sp|Q9BQE3|TBA1C_HUMAN,tr|C9JJQ8|C9JJQ8_HUMAN,tr|F8VS66|F8VS66_HUMAN,tr|F8VWV9|F8VWV9_HUMAN,tr|F8VRZ4|F8VRZ4_HUMAN,tr|F8VVB9|F8VVB9_HUMAN,tr|C9JQ00|C9JQ00_HUMAN,tr|C9JEV8|C9JEV8_HUMAN,tr|A0A7P0TA31|A0A7P0TA31_HUMAN,tr|A0A1W2PQM2|A0A1W2PQM2_HUMAN,tr|F5H5D3|F5H5D3_HUMAN,tr|C9J2C0|C9J2C0_HUMAN,tr|C9K0S6|C9K0S6_HUMAN,tr|C9JDL2|C9JDL2_HUMAN,tr|F8VQQ4|F8VQQ4_HUMAN,tr|F8VX09|F8VX09_HUMAN,tr|A0A7P0T945|A0A7P0T945_HUMAN" 24 1022.4417 0.62 76392 5386 2 1022.440167 512.2281 Tubulin alpha-8 chain OS=Homo sapiens OX=9606 GN=TUBA8 PE=1 SV=1 4.37 1508.8 - 5.30E+07 - - - -1.5355 - 1.68 0.535 - 298 1 2 0 -0.0016 9 0 0 0 1.47E+09 2.36E+09 - - - 4.4929 0.9994 221125_WJC_METTL3_EV_vs_WT_F06.05390.05390.2 0.0667 18-Sep K.GQGPGEVDPK.V sp|P17568|NDUB7_HUMAN 1 982.472 1.74 76394 5390 2 982.473602 492.2433 NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 7 OS=Homo sapiens OX=9606 GN=NDUFB7 PE=1 SV=4 4.37 1509.1 - 1.02E+07 - - - 1.657 - 1.815 0.382 - 251.1 1 2 0 0.0016 10 0 0 0 2.63E+08 1.51E+08 - - - 3.5258 0.8714 221125_WJC_METTL3_EV_vs_WT_F06.05399.05399.2 4.58 12-Aug R.RLEEQIK.N "sp|P55197|AF10_HUMAN,sp|Q15075|EEA1_HUMAN,tr|Q5JT35|Q5JT35_HUMAN" 3 914.5185 4.6 76401 5399 2 914.515334 458.2665 Protein AF-10 OS=Homo sapiens OX=9606 GN=MLLT10 PE=1 SV=2 6.14 1509.9 - 4.82E+06 - - - -3.4958 - 1.384 0.002 - 324.3 1 2 0 -0.0032 7 0 0 0 8.92E+07 1.94E+07 - - - 0.0845 0.9694 221125_WJC_METTL3_EV_vs_WT_F06.05400.05400.2 0.0359 14/18 K.ALQSGPPQSR[166.11].R sp|O00425|IF2B3_HUMAN 1 1049.5493 2.39 76402 5400 2 1049.554255 525.7819 Insulin-like growth factor 2 mRNA-binding protein 3 OS=Homo sapiens OX=9606 GN=IGF2BP3 PE=1 SV=2 9.79 1510 - 3.98E+06 - - - 4.6953 - 1.907 0.13 - 1006.2 1 2 0 0.0049 10 0 0 0 5.43E+08 2.27E+08 - - - 1.8015 0.9997 221125_WJC_METTL3_EV_vs_WT_F06.05403.05403.2 2.36E-05 18-Nov K.AAQELQEGQR[166.11].C "sp|P35520|CBS_HUMAN,tr|H7C2H4|H7C2H4_HUMAN" 2 1138.5606 0.6 76405 5403 2 1138.557979 570.2876 Cystathionine beta-synthase OS=Homo sapiens OX=9606 GN=CBS PE=1 SV=2 4.53 1510.2 - 2.62E+06 - - - -2.3196 - 2.187 0.516 - 582 1 2 0 -0.0026 10 0 0 0 3.98E+07 6.60E+07 - - - 5.0356 0.9537 221125_WJC_METTL3_EV_vs_WT_F06.05406.05406.2 1.23 16-Jun K.YNDVSDLC[160.03]K.L sp|Q8IXT1|DDIAS_HUMAN 1 1112.4808 3.81 76406 5406 2 1112.485116 557.2477 DNA damage-induced apoptosis suppressor protein OS=Homo sapiens OX=9606 GN=DDIAS PE=2 SV=2 4.21 1510.6 - 2.08E+07 - - - 3.8571 - 1.301 0.165 - 185.2 1 2 0 0.0043 9 0 0 0 2.88E+08 7.56E+07 - - - 1.0196 0.9992 221125_WJC_METTL3_EV_vs_WT_F06.05409.05409.2 2.96E-05 14/22 R.GPPASSPAPAPK[136.11].F "sp|Q15942|ZYX_HUMAN,tr|H7C3D3|H7C3D3_HUMAN,tr|H0Y2Y8|H0Y2Y8_HUMAN" 3 1083.5804 4.35 76409 5409 2 1083.576941 542.7975 Zyxin OS=Homo sapiens OX=9606 GN=ZYX PE=1 SV=1 8.75 1510.9 - 3.36E+06 - - - -3.2005 - 2.56 0.388 - 503.5 1 2 0 -0.0035 12 0 0 0 2.94E+08 6.76E+07 - - - 4.379 0.9968 221125_WJC_METTL3_EV_vs_WT_F06.05410.05410.2 0.000156 13/18 R.ER[166.11]PPEEVAAR[166.11].L "sp|Q16891|MIC60_HUMAN,tr|B9A067|B9A067_HUMAN,tr|A0A087WYS0|A0A087WYS0_HUMAN,tr|C9J406|C9J406_HUMAN" 4 1172.6053 1.37 76410 5410 2 1172.598991 587.3099 MICOS complex subunit MIC60 OS=Homo sapiens OX=9606 GN=IMMT PE=1 SV=1 4.79 1511 - 1.90E+06 - - - -5.3599 - 2.466 0.428 - 377.1 1 2 0 -0.0063 10 0 0 0 8.67E+07 6.33E+07 - - - 4.7197 0.9971 221125_WJC_METTL3_EV_vs_WT_F06.05415.05415.2 0.0346 14-Aug K.IHQETFGK[136.11].S "sp|Q15393|SF3B3_HUMAN,tr|J3QL37|J3QL37_HUMAN" 2 966.5014 1.32 76413 5415 2 966.498968 484.258 Splicing factor 3B subunit 3 OS=Homo sapiens OX=9606 GN=SF3B3 PE=1 SV=4 6.75 1511.5 - 6.94E+06 - - - -2.5473 - 1.63 0.265 - 325.2 1 2 0 -0.0025 8 0 0 0 2.19E+08 1.66E+08 - - - 2.4711 0.9981 221125_WJC_METTL3_EV_vs_WT_F06.05416.05416.2 0.0088 14-Jul R.SVGQYDNR.G "sp|P13861|KAP2_HUMAN,tr|H7C1L0|H7C1L0_HUMAN" 2 937.4254 1.49 76414 5416 2 937.424716 469.72 cAMP-dependent protein kinase type II-alpha regulatory subunit OS=Homo sapiens OX=9606 GN=PRKAR2A PE=1 SV=2 5.55 1511.6 - 3.99E+06 - - - -0.6859 - 1.248 0.295 - 155.7 1 2 0 -0.0006 8 0 0 0 1.21E+08 8.12E+07 - - - 1.8878 0.896 221125_WJC_METTL3_EV_vs_WT_F06.05430.05430.2 0.151 16-Jun A.QGEDNSEIK[136.11].E "sp|Q9UBW5|BIN2_HUMAN,tr|S4R418|S4R418_HUMAN" 2 1026.4709 1.8 76425 5430 2 1026.470059 514.2427 Bridging integrator 2 OS=Homo sapiens OX=9606 GN=BIN2 PE=1 SV=3 4.14 1513 - 1.08E+07 - - - -0.8368 - 1.467 0.239 - 186.8 1 1 0 -0.0009 9 0 0 0 3.84E+08 2.14E+08 - - - 1.9147 0.9997 221125_WJC_METTL3_EV_vs_WT_F06.05432.05432.3 0.000136 Nov-36 R.ERPPEEVAAR.L "sp|Q16891|MIC60_HUMAN,tr|B9A067|B9A067_HUMAN,tr|A0A087WYS0|A0A087WYS0_HUMAN,tr|C9J406|C9J406_HUMAN" 4 1152.5887 1.47 76426 5432 3 1152.58727 385.2035 MICOS complex subunit MIC60 OS=Homo sapiens OX=9606 GN=IMMT PE=1 SV=1 4.79 1513.2 - 3.05E+07 - - - -1.2719 - 2.035 0.335 - 266.3 1 2 0 -0.0015 10 0 0 0 5.30E+08 3.61E+08 - - - 4.3495 0.9994 221125_WJC_METTL3_EV_vs_WT_F06.05433.05433.2 0.00135 14-Aug R.SHVLPEGR[166.11].S sp|Q8IU81|I2BP1_HUMAN 1 903.4802 0.61 76427 5433 2 903.479097 452.7474 Interferon regulatory factor 2-binding protein 1 OS=Homo sapiens OX=9606 GN=IRF2BP1 PE=1 SV=1 6.47 1513.3 - 9.10E+06 - - - -1.2042 - 1.611 0.355 - 330.6 1 2 0 -0.0011 8 0 0 0 1.48E+08 2.41E+08 - - - 3.1009 0.9979 221125_WJC_METTL3_EV_vs_WT_F06.05434.05434.2 0.033 14-Jul K.YHNVGLSK.C "sp|Q14103|HNRPD_HUMAN,tr|H0Y8G5|H0Y8G5_HUMAN,tr|H0YA96|H0YA96_HUMAN" 3 916.4767 1.16 76428 5434 2 916.477797 459.2456 Heterogeneous nuclear ribonucleoprotein D0 OS=Homo sapiens OX=9606 GN=HNRNPD PE=1 SV=1 8.6 1513.3 - 6.35E+06 - - - 1.2341 - 1.335 0.291 - 184.8 1 2 0 0.0011 8 0 0 0 3.16E+08 2.72E+08 - - - 2.0614 0.9982 221125_WJC_METTL3_EV_vs_WT_F06.05436.05436.2 0.00465 18-Sep K.AAQELQEGQR.C "sp|P35520|CBS_HUMAN,tr|H7C2H4|H7C2H4_HUMAN" 2 1128.5523 0.6 76430 5436 2 1128.549489 565.2835 Cystathionine beta-synthase OS=Homo sapiens OX=9606 GN=CBS PE=1 SV=2 4.53 1513.4 - 2.47E+06 - - - -2.5351 - 1.732 0.312 - 409.6 1 2 0 -0.0029 10 0 0 0 3.98E+07 6.60E+07 - - - 2.8777 0.9999 221125_WJC_METTL3_EV_vs_WT_F06.05438.05438.2 0.000176 15/24 R.LEGGSGGDSEVQR[166.11].T "sp|P62195|PRS8_HUMAN,tr|J3QQM1|J3QQM1_HUMAN" 2 1299.593 0.82 76432 5438 2 1299.592186 650.8038 26S proteasome regulatory subunit 8 OS=Homo sapiens OX=9606 GN=PSMC5 PE=1 SV=1 4.14 1513.7 - 1.78E+06 - - - -0.6587 - 2.759 0.542 - 836.1 1 2 0 -0.0009 13 0 0 0 1.96E+07 2.39E+07 - - - 5.6486 1 221125_WJC_METTL3_EV_vs_WT_F06.05441.05441.2 0.000408 14/24 R.LEGGSGGDSEVQR.T "sp|P62195|PRS8_HUMAN,tr|J3QQM1|J3QQM1_HUMAN" 2 1289.5848 0.82 76435 5441 2 1289.582296 645.7997 26S proteasome regulatory subunit 8 OS=Homo sapiens OX=9606 GN=PSMC5 PE=1 SV=1 4.14 1513.9 - 954653 - - - -1.92 - 2.711 0.558 - 758.4 1 2 0 -0.0025 13 0 0 0 1.96E+07 2.39E+07 - - - 5.7213 0.9996 221125_WJC_METTL3_EV_vs_WT_F06.05443.05443.2 0.000563 18-Dec K.LYAVHQEGNK[136.11].N "sp|P50990|TCPQ_HUMAN,tr|H7C2U0|H7C2U0_HUMAN" 2 1165.5971 0.38 76437 5443 2 1165.59376 583.8058 T-complex protein 1 subunit theta OS=Homo sapiens OX=9606 GN=CCT8 PE=1 SV=4 6.75 1514.2 - 909610 - - - -2.8844 - 2.452 0.498 - 636.4 1 2 0 -0.0034 10 0 0 0 2.27E+08 5.94E+08 - - - 5.2217 0.9421 221125_WJC_METTL3_EV_vs_WT_F06.05446.05446.2 0.00572 24-Aug Q.LHPVADSSPAGAK.W "sp|Q8IXM2|BAP18_HUMAN,tr|H0YIS7|H0YIS7_HUMAN,tr|F8W038|F8W038_HUMAN,tr|F8W1H0|F8W1H0_HUMAN" 4 1248.6463 -1 76440 5446 2 1248.644196 625.3304 Chromatin complexes subunit BAP18 OS=Homo sapiens OX=9606 GN=BAP18 PE=1 SV=1 6.74 1514.6 - 364088 - - - -1.645 - 1.498 0.374 - 160.2 1 1 0 -0.0021 13 0 0 0 0.00E+00 0.00E+00 - - - 2.8399 0.9999 221125_WJC_METTL3_EV_vs_WT_F06.05451.05451.3 0.000428 Oct-36 K.LYAVHQEGNK.N "sp|P50990|TCPQ_HUMAN,tr|H7C2U0|H7C2U0_HUMAN" 2 1157.5829 0.39 76443 5451 3 1157.582796 386.8683 T-complex protein 1 subunit theta OS=Homo sapiens OX=9606 GN=CCT8 PE=1 SV=4 6.75 1515 - 2.05E+07 - - - -0.1088 - 1.975 0.421 - 116.4 1 2 0 -0.0001 10 0 0 0 1.17E+09 2.98E+09 - - - 5.2213 0.9999 221125_WJC_METTL3_EV_vs_WT_F06.05452.05452.2 4.72E-06 14-Nov K.YHNVGLSK[136.11].C "sp|Q14103|HNRPD_HUMAN,tr|H0Y8G5|H0Y8G5_HUMAN,tr|H0YA96|H0YA96_HUMAN" 3 924.4909 1.16 76444 5452 2 924.490892 463.2527 Heterogeneous nuclear ribonucleoprotein D0 OS=Homo sapiens OX=9606 GN=HNRNPD PE=1 SV=1 8.6 1515.1 - 2.04E+07 - - - 0.0281 - 2.401 0.471 - 662.4 1 2 0 0 8 0 0 0 3.16E+08 2.72E+08 - - - 5.1614 0.8712 221125_WJC_METTL3_EV_vs_WT_F06.05453.05453.2 1.29 14-Jul K.HTDESLGD.C "sp|Q86U44|MTA70_HUMAN,tr|H0YFV6|H0YFV6_HUMAN" 2 872.3512 - 76445 5453 2 872.350917 437.1829 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 4.27 1515.1 - 1.35E+07 - - - -0.3141 - 1.432 0.204 - 198.6 1 1 0 -0.0003 8 0 0 0 - - - - - 1.6306 0.9982 221125_WJC_METTL3_EV_vs_WT_F06.05454.05454.2 0.0722 14-Jun R.SHVLPEGR.S sp|Q8IU81|I2BP1_HUMAN 1 893.4719 0.74 76446 5454 2 893.470607 447.7432 Interferon regulatory factor 2-binding protein 1 OS=Homo sapiens OX=9606 GN=IRF2BP1 PE=1 SV=1 6.47 1515.2 - 1.27E+07 - - - -1.464 - 1.505 0.263 - 188.3 1 2 0 -0.0013 8 0 0 0 1.28E+08 1.73E+08 - - - 2.216 1 221125_WJC_METTL3_EV_vs_WT_F06.05456.05456.3 7.22E-06 15/36 R.K[136.11]QDSGHLDLR[166.11].N "sp|Q86U44|MTA70_HUMAN,tr|B4E349|B4E349_HUMAN,tr|F5H6D8|F5H6D8_HUMAN,tr|B4DTN4|B4DTN4_HUMAN" 4 1185.6221 5.96 76448 5456 3 1185.62199 396.2146 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 6.75 1515.2 - 7.54E+06 - - - -0.097 - 2.455 0.528 - 272.5 1 2 0 -0.0001 10 0 0 0 8.18E+08 1.37E+08 - - - 7.0496 0.9998 221125_WJC_METTL3_EV_vs_WT_F06.05457.05457.2 0.0011 16-Sep K.EGSALSHVR[166.11].K "sp|Q3MHD2|LSM12_HUMAN,tr|K7ELG9|K7ELG9_HUMAN" 2 964.4966 0.35 76449 5457 2 964.496002 483.2556 Protein LSM12 homolog OS=Homo sapiens OX=9606 GN=LSM12 PE=1 SV=2 6.85 1515.3 - 5.63E+06 - - - -0.5817 - 1.809 0.479 - 288.3 1 2 0 -0.0006 9 0 0 0 6.90E+07 1.97E+08 - - - 4.2936 0.9999 221125_WJC_METTL3_EV_vs_WT_F06.05458.05458.2 6.13E-06 18-Sep R.EADPESEADR.A "sp|O00461|GOLI4_HUMAN,tr|F8W785|F8W785_HUMAN" 2 1117.4524 1.62 76450 5458 2 1117.452125 559.7335 Golgi integral membrane protein 4 OS=Homo sapiens OX=9606 GN=GOLIM4 PE=1 SV=1 3.83 1515.3 - 4.96E+06 - - - -0.2112 - 1.961 0.549 - 347.8 1 2 0 -0.0002 10 0 0 0 6.48E+07 4.00E+07 - - - 4.9757 0.9999 221125_WJC_METTL3_EV_vs_WT_F06.05459.05459.2 6.96E-05 18-Sep R.EADPESEADR[166.11].A "sp|O00461|GOLI4_HUMAN,tr|F8W785|F8W785_HUMAN" 2 1127.4606 1.62 76451 5459 2 1127.460374 564.7376 Golgi integral membrane protein 4 OS=Homo sapiens OX=9606 GN=GOLIM4 PE=1 SV=1 3.83 1515.4 - 3.09E+06 - - - -0.2279 - 1.778 0.59 - 406.7 1 2 0 -0.0003 10 0 0 0 6.48E+07 4.00E+07 - - - 5.005 0.9998 221125_WJC_METTL3_EV_vs_WT_F06.05460.05460.2 0.000266 18-Sep K.LYAVHQEGNK.N "sp|P50990|TCPQ_HUMAN,tr|H7C2U0|H7C2U0_HUMAN" 2 1157.5829 0.38 76452 5460 2 1157.584305 579.7987 T-complex protein 1 subunit theta OS=Homo sapiens OX=9606 GN=CCT8 PE=1 SV=4 6.75 1515.4 - 2.58E+06 - - - 1.1947 - 1.925 0.488 - 280.3 1 2 0 0.0014 10 0 0 0 2.27E+08 5.94E+08 - - - 4.473 0.9993 221125_WJC_METTL3_EV_vs_WT_F06.05461.05461.2 0.00231 12-Jul K.SSDTFR[166.11]Q.- sp|Q8IWC1|MA7D3_HUMAN 1 849.3856 1.07 76453 5461 2 849.385328 425.7001 MAP7 domain-containing protein 3 OS=Homo sapiens OX=9606 GN=MAP7D3 PE=1 SV=2 5.55 1515.5 - 1.87E+06 - - - -0.3391 - 1.394 0.355 - 310.3 1 2 0 -0.0003 7 0 0 0 6.29E+07 5.86E+07 - - - 2.7155 0.9998 221125_WJC_METTL3_EV_vs_WT_F06.05462.05462.2 0.000222 18-Oct R.ADGSQMAEER.L sp|Q5VZE5|NAA35_HUMAN 1 1092.4506 1.33 76454 5462 2 1092.452474 547.2326 "N-alpha-acetyltransferase 35, NatC auxiliary subunit OS=Homo sapiens OX=9606 GN=NAA35 PE=1 SV=1" 4.14 1515.6 - 659036 - - - 1.7273 - 2.069 0.54 - 397 1 2 0 0.0019 10 0 0 0 8.07E+06 6.06E+06 - - - 5.0583 0.9999 221125_WJC_METTL3_EV_vs_WT_F06.05463.05463.2 4.39E-05 18-Oct R.K[136.11]QDSGHLDLR[166.11].N "sp|Q86U44|MTA70_HUMAN,tr|B4E349|B4E349_HUMAN,tr|F5H6D8|F5H6D8_HUMAN,tr|B4DTN4|B4DTN4_HUMAN" 4 1185.6221 20.38 76455 5463 2 1185.622291 593.8183 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 6.75 1515.7 - 427016 - - - 0.1569 - 2.074 0.485 - 292.1 1 2 0 0.0002 10 0 0 0 1.38E+08 6.76E+06 - - - 4.6593 0.9998 221125_WJC_METTL3_EV_vs_WT_F06.05466.05466.2 0.00139 16-Sep R.SEIQAEQDR[166.11].K "sp|Q16891|MIC60_HUMAN,tr|B9A067|B9A067_HUMAN,tr|C9J406|C9J406_HUMAN,tr|H7C463|H7C463_HUMAN" 4 1084.5024 1.43 76456 5466 2 1084.501456 543.2585 MICOS complex subunit MIC60 OS=Homo sapiens OX=9606 GN=IMMT PE=1 SV=1 4.14 1516.1 - 1.50E+07 - - - -0.9036 - 1.916 0.484 - 427.3 1 2 0 -0.001 9 0 0 0 1.18E+09 8.20E+08 - - - 4.4967 0.9989 221125_WJC_METTL3_EV_vs_WT_F06.05468.05468.2 0.101 14-Aug R.R[166.11]AEEQMLK[136.11].E sp|Q14152|EIF3A_HUMAN 1 1021.5345 1.05 76458 5468 2 1021.53369 511.7745 Eukaryotic translation initiation factor 3 subunit A OS=Homo sapiens OX=9606 GN=EIF3A PE=1 SV=1 6.14 1516.2 - 8.45E+06 - - - -0.8272 - 1.72 0.227 - 339.1 1 2 0 -0.0008 8 0 0 0 9.17E+07 8.77E+07 - - - 2.353 0.9995 221125_WJC_METTL3_EV_vs_WT_F06.05469.05469.2 0.00159 12-Sep K.K[136.11]GEDFVK[136.11].T "sp|P40926|MDHM_HUMAN,tr|G3XAL0|G3XAL0_HUMAN" 2 837.4567 1.36 76459 5469 2 837.455882 419.7356 "Malate dehydrogenase, mitochondrial OS=Homo sapiens OX=9606 GN=MDH2 PE=1 SV=3" 6.07 1516.3 - 7.49E+06 - - - -0.9995 - 1.67 0.346 - 272.7 1 2 0 -0.0008 7 0 0 0 8.09E+07 5.94E+07 - - - 3.2212 0.8885 221125_WJC_METTL3_EV_vs_WT_F06.05471.05471.2 0.0391 20-May S.NDSTDGEPEEK[136.11].R "sp|O14981|BTAF1_HUMAN,tr|A0A0A0MTH9|A0A0A0MTH9_HUMAN" 2 1227.4983 0.89 76461 5471 2 1227.498949 614.7564 TATA-binding protein-associated factor 172 OS=Homo sapiens OX=9606 GN=BTAF1 PE=1 SV=2 3.83 1516.5 - 1.40E+06 - - - 0.5654 - 1.066 0.356 - 67.3 1 1 0 0.0007 11 0 0 0 1.22E+07 1.37E+07 - - - 1.8431 0.9619 221125_WJC_METTL3_EV_vs_WT_F06.05475.05475.2 0.0192 14-Oct Y.AVHQEGNK[136.11].N "sp|P50990|TCPQ_HUMAN,tr|H7C2U0|H7C2U0_HUMAN" 2 889.4497 0.37 76463 5475 2 889.4485 445.7321 T-complex protein 1 subunit theta OS=Homo sapiens OX=9606 GN=CCT8 PE=1 SV=4 6.79 1516.9 - 9.82E+06 - - - -1.3818 - 1.559 0.371 - 368.1 1 1 0 -0.0012 8 0 0 0 4.67E+07 1.26E+08 - - - 3.12 0.9993 221125_WJC_METTL3_EV_vs_WT_F06.05476.05476.2 0.0194 12-Jun K.SSDTFRQ.- sp|Q8IWC1|MA7D3_HUMAN 1 839.3773 1.07 76464 5476 2 839.376428 420.6959 MAP7 domain-containing protein 3 OS=Homo sapiens OX=9606 GN=MAP7D3 PE=1 SV=2 5.55 1517 - 6.14E+06 - - - -1.0937 - 1.318 0.406 - 150.5 1 2 0 -0.0009 7 0 0 0 6.29E+07 5.86E+07 - - - 2.9143 0.845 221125_WJC_METTL3_EV_vs_WT_F06.05482.05482.2 0.14 14-Jun R.RQEWFC[160.03]TR[166.11].V "sp|Q9BWT7|CAR10_HUMAN,tr|B0QYC4|B0QYC4_HUMAN" 2 1191.5483 - 76469 5482 2 1191.555067 596.7814 Caspase recruitment domain-containing protein 10 OS=Homo sapiens OX=9606 GN=CARD10 PE=1 SV=2 8.25 1517.5 - 527844 - - - 5.6951 - 1.261 0.172 - 120.3 1 2 0 0.0068 8 0 0 0 - - - - - 1.0087 0.9968 221125_WJC_METTL3_EV_vs_WT_F06.05486.05486.2 0.00256 12-Aug K.KGEDFVK.T "sp|P40926|MDHM_HUMAN,tr|G3XAL0|G3XAL0_HUMAN" 2 821.4283 1.27 76471 5486 2 821.427175 411.7214 "Malate dehydrogenase, mitochondrial OS=Homo sapiens OX=9606 GN=MDH2 PE=1 SV=3" 6.07 1518 - 5.78E+06 - - - -1.3927 - 1.534 0.179 - 218.8 1 2 0 -0.0011 7 0 0 0 7.38E+07 5.82E+07 - - - 1.7185 0.9989 221125_WJC_METTL3_EV_vs_WT_F06.05487.05487.2 0.52 14-Sep K.RAPAFEGR.L sp|P01833|PIGR_HUMAN 1 902.4722 0.52 76472 5487 2 902.471337 452.2434 Polymeric immunoglobulin receptor OS=Homo sapiens OX=9606 GN=PIGR PE=1 SV=4 9.6 1518 - 4.01E+06 - - - -1.0106 - 1.683 0.244 - 180.4 1 2 0 -0.0009 8 0 0 0 1.17E+08 2.23E+08 - - - 2.4129 0.9965 221125_WJC_METTL3_EV_vs_WT_F06.05492.05492.2 0.0972 14-Jun K.SSC[160.03]SEFSK[136.11].E sp|Q96N67|DOCK7_HUMAN 1 938.3895 0.77 76475 5492 2 938.388897 470.202 Dedicator of cytokinesis protein 7 OS=Homo sapiens OX=9606 GN=DOCK7 PE=1 SV=4 5.72 1518.7 - 1.70E+06 - - - -0.6394 - 1.185 0.251 - 122.9 1 2 0 -0.0006 8 0 0 0 2.30E+07 3.00E+07 - - - 1.4066 0.9973 221125_WJC_METTL3_EV_vs_WT_F06.05499.05499.2 0.157 14-Jul R.QQQEEALR.R "sp|Q6Y7W6|GGYF2_HUMAN,tr|A0A7I2V3H7|A0A7I2V3H7_HUMAN,tr|I1E4Y6|I1E4Y6_HUMAN,tr|A0A7I2V516|A0A7I2V516_HUMAN,tr|A0A7I2V3H0|A0A7I2V3H0_HUMAN,tr|A0A7I2V361|A0A7I2V361_HUMAN,tr|E7ESB6|E7ESB6_HUMAN" 7 1000.4938 2.78 76480 5499 2 1000.491886 501.2542 GRB10-interacting GYF protein 2 OS=Homo sapiens OX=9606 GN=GIGYF2 PE=1 SV=1 4.53 1519.4 - 7.44E+06 - - - -1.8851 - 1.518 0.244 - 285.9 1 2 0 -0.0019 8 0 0 0 3.88E+08 1.39E+08 - - - 2.1014 0.9625 221125_WJC_METTL3_EV_vs_WT_F06.05500.05500.2 0.249 14-Aug R.EK[136.11]VESELR[166.11].S "sp|P27348|1433T_HUMAN,tr|E9PG15|E9PG15_HUMAN" 2 1006.5414 0.76 76481 5500 2 1006.540571 504.278 14-3-3 protein theta OS=Homo sapiens OX=9606 GN=YWHAQ PE=1 SV=1 4.79 1519.4 - 4.01E+06 - - - -0.8186 - 1.482 0.166 - 262.4 1 2 1 -0.0008 8 0 0 0 7.57E+07 1.00E+08 - - - 1.4533 0.9882 221125_WJC_METTL3_EV_vs_WT_F06.05505.05505.2 0.105 16-Sep R.AEENALQQK.A sp|P15924|DESP_HUMAN 1 1029.5091 5.46 76484 5505 2 1029.514364 515.7618 Desmoplakin OS=Homo sapiens OX=9606 GN=DSP PE=1 SV=3 4.53 1520 - 4.94E+06 - - - 5.1248 - 1.799 0.296 - 318.8 1 2 0 0.0053 9 0 0 0 1.50E+08 2.75E+07 - - - 2.9245 0.8911 221125_WJC_METTL3_EV_vs_WT_F06.05511.05511.2 0.0116 16-Nov K.LREENDIAR.G "sp|Q53EZ4|CEP55_HUMAN,tr|H0Y432|H0Y432_HUMAN" 2 1114.5731 1.83 76488 5511 2 1114.577458 558.2938 Centrosomal protein of 55 kDa OS=Homo sapiens OX=9606 GN=CEP55 PE=1 SV=3 4.68 1520.7 - 1.03E+06 - - - 3.9235 - 1.85 0.188 - 256.9 1 2 1 0.0044 9 0 0 0 1.19E+07 6.49E+06 - - - 2.208 0.9966 221125_WJC_METTL3_EV_vs_WT_F06.05512.05512.2 0.123 16-Jul K.K[136.11]VVDYTTAK[136.11].E "sp|P62820|RAB1A_HUMAN,tr|E7END7|E7END7_HUMAN" 2 1039.5885 1.13 76489 5512 2 1039.586098 520.8015 Ras-related protein Rab-1A OS=Homo sapiens OX=9606 GN=RAB1A PE=1 SV=3 8.5 1520.8 - 4.68E+06 - - - -2.273 - 1.343 0.305 - 158.9 1 2 0 -0.0024 9 0 0 0 5.92E+07 5.22E+07 - - - 2.1462 0.9124 221125_WJC_METTL3_EV_vs_WT_F06.05517.05517.2 0.019 14-Sep R.EKVESELR.S "sp|P27348|1433T_HUMAN,tr|E9PG15|E9PG15_HUMAN" 2 988.5189 0.75 76492 5517 2 988.517032 495.2667 14-3-3 protein theta OS=Homo sapiens OX=9606 GN=YWHAQ PE=1 SV=1 4.79 1521.2 - 5.20E+06 - - - -1.915 - 1.758 0.066 - 360.3 1 2 1 -0.0019 8 0 0 0 7.57E+07 1.00E+08 - - - 1.2294 0.999 221125_WJC_METTL3_EV_vs_WT_F06.05518.05518.2 0.00615 14-Aug K.SVSDYDGK.L "sp|P07237|PDIA1_HUMAN,tr|A0A7P0TA97|A0A7P0TA97_HUMAN,tr|A0A7P0T8C0|A0A7P0T8C0_HUMAN,tr|H7BZ94|H7BZ94_HUMAN,tr|A0A7P0TA71|A0A7P0TA71_HUMAN,tr|I3L4M2|I3L4M2_HUMAN,tr|A0A7P0T9D6|A0A7P0T9D6_HUMAN,tr|A0A7P0T9K9|A0A7P0T9K9_HUMAN,tr|H0Y3Z3|H0Y3Z3_HUMAN,tr|A0A7P0TA35|A0A7P0TA35_HUMAN,tr|I3L514|I3L514_HUMAN,tr|A0A7P0TB26|A0A7P0TB26_HUMAN,tr|A0A7P0T9U6|A0A7P0T9U6_HUMAN,tr|I3L3P5|I3L3P5_HUMAN,tr|A0A7P0T8J3|A0A7P0T8J3_HUMAN,tr|A0A7P0T8X1|A0A7P0T8X1_HUMAN" 16 869.3767 0.77 76493 5518 2 869.375344 435.6956 Protein disulfide-isomerase OS=Homo sapiens OX=9606 GN=P4HB PE=1 SV=3 4.21 1521.3 - 5.78E+06 - - - -1.5333 - 1.31 0.398 - 180.9 1 2 0 -0.0013 8 0 0 0 9.16E+07 1.19E+08 - - - 2.7946 0.9981 221125_WJC_METTL3_EV_vs_WT_F06.05519.05519.2 0.00409 14-Jul K.IAVHC[160.03]TVR.G "sp|P62913|RL11_HUMAN,tr|Q5VVC8|Q5VVC8_HUMAN" 2 954.5069 0.66 76494 5519 2 954.504605 478.2607 60S ribosomal protein L11 OS=Homo sapiens OX=9606 GN=RPL11 PE=1 SV=2 8.26 1521.3 - 2.99E+06 - - - -2.4253 - 1.525 0.331 - 230.3 1 2 0 -0.0023 8 0 0 0 3.82E+07 5.79E+07 - - - 2.7578 1 221125_WJC_METTL3_EV_vs_WT_F06.05521.05521.2 1.87E-06 14/24 R.GVGSGGQGPPPPR[166.11].R sp|P48634|PRC2A_HUMAN 1 1171.5973 1.03 76496 5521 2 1171.595572 586.8059 Protein PRRC2A OS=Homo sapiens OX=9606 GN=PRRC2A PE=1 SV=3 9.75 1521.5 - 1.81E+06 - - - -1.5091 - 2.69 0.603 - 698.4 1 2 0 -0.0018 13 0 0 0 7.83E+07 7.58E+07 - - - 6.0339 0.9843 221125_WJC_METTL3_EV_vs_WT_F06.05526.05526.2 0.366 12-May R.NTTIPTK[136.11].K "sp|P38646|GRP75_HUMAN,sp|P54652|HSP72_HUMAN,sp|P11142|HSP7C_HUMAN,tr|E9PNE6|E9PNE6_HUMAN,tr|A8K7Q2|A8K7Q2_HUMAN,tr|E9PKE3|E9PKE3_HUMAN,tr|A0A7I2V2S7|A0A7I2V2S7_HUMAN,tr|A0A7I2V2G2|A0A7I2V2G2_HUMAN,tr|E9PS65|E9PS65_HUMAN,tr|A0A7I2YQB2|A0A7I2YQB2_HUMAN,tr|D6RCD7|D6RCD7_HUMAN" 11 781.4425 0.17 76499 5526 2 781.441452 391.7285 "Stress-70 protein, mitochondrial OS=Homo sapiens OX=9606 GN=HSPA9 PE=1 SV=2" 8.75 1522 - 5.13E+07 - - - -1.3654 - 1.299 0.093 - 133 1 2 0 -0.0011 7 0 0 0 2.25E+08 1.31E+09 - - - 0.5564 0.9996 221125_WJC_METTL3_EV_vs_WT_F06.05530.05530.2 5.40E-06 20-Nov R.EAEC[160.03]VEADSGR.L "sp|Q14533|KRT81_HUMAN,sp|P78386|KRT85_HUMAN,sp|O43790|KRT86_HUMAN,sp|P78385|KRT83_HUMAN,tr|A0A087X106|A0A087X106_HUMAN" 5 1221.4932 999 76503 5530 2 1221.489758 611.7539 "Keratin, type II cuticular Hb1 OS=Homo sapiens OX=9606 GN=KRT81 PE=1 SV=3" 4 1522.3 - 568478 - - - -2.8015 - 2.064 0.588 - 524.8 1 2 0 -0.0034 11 0 0 0 2.05E+07 0.00E+00 - - - 5.3432 0.9681 221125_WJC_METTL3_EV_vs_WT_F06.05533.05533.2 0.00372 12-Aug V.TYADHSK[136.11].L "sp|Q86U44|MTA70_HUMAN,tr|F5H6D8|F5H6D8_HUMAN,tr|H0YFV6|H0YFV6_HUMAN,tr|B4DTN4|B4DTN4_HUMAN" 4 828.3857 0.02 76505 5533 2 828.38469 415.2001 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 6.41 1522.7 - 7.77E+06 - - - -1.2579 - 1.382 0.43 - 200.6 1 1 0 -0.001 7 0 0 0 2.85E+06 1.45E+08 - - - 3.2418 0.9998 221125_WJC_METTL3_EV_vs_WT_F06.05535.05535.2 3.14E-07 22-Dec R.GPAGDATVASEK.E "sp|Q15758|AAAT_HUMAN,tr|M0QXM4|M0QXM4_HUMAN" 2 1101.5302 1.74 76506 5535 2 1101.528471 551.7724 Neutral amino acid transporter B(0) OS=Homo sapiens OX=9606 GN=SLC1A5 PE=1 SV=2 4.37 1522.9 - 3.06E+06 - - - -1.586 - 2.56 0.46 - 449.5 1 2 0 -0.0017 12 0 0 0 5.53E+07 3.18E+07 - - - 4.9113 1 221125_WJC_METTL3_EV_vs_WT_F06.05536.05536.2 4.75E-06 22-Dec R.GPAGDATVASEK[136.11].E "sp|Q15758|AAAT_HUMAN,tr|M0QXM4|M0QXM4_HUMAN" 2 1109.5444 1.73 76507 5536 2 1109.542905 555.7795 Neutral amino acid transporter B(0) OS=Homo sapiens OX=9606 GN=SLC1A5 PE=1 SV=2 4.37 1522.9 - 1.96E+06 - - - -1.3636 - 2.59 0.567 - 436.5 1 2 0 -0.0015 12 0 0 0 5.41E+07 3.12E+07 - - - 5.7324 0.9866 221125_WJC_METTL3_EV_vs_WT_F06.05541.05541.2 0.183 12-Jun R.NTTIPTK.K "sp|P38646|GRP75_HUMAN,sp|P54652|HSP72_HUMAN,sp|P11142|HSP7C_HUMAN,tr|E9PNE6|E9PNE6_HUMAN,tr|A8K7Q2|A8K7Q2_HUMAN,tr|E9PKE3|E9PKE3_HUMAN,tr|A0A7I2V2S7|A0A7I2V2S7_HUMAN,tr|A0A7I2V2G2|A0A7I2V2G2_HUMAN,tr|E9PS65|E9PS65_HUMAN,tr|A0A7I2YQB2|A0A7I2YQB2_HUMAN,tr|D6RCD7|D6RCD7_HUMAN" 11 773.4283 0.17 76510 5541 2 773.427777 387.7214 "Stress-70 protein, mitochondrial OS=Homo sapiens OX=9606 GN=HSPA9 PE=1 SV=2" 8.75 1523.5 - 1.73E+07 - - - -0.7008 - 1.391 0.052 - 184.4 1 2 0 -0.0005 7 0 0 0 2.25E+08 1.31E+09 - - - 0.4706 0.9977 221125_WJC_METTL3_EV_vs_WT_F06.05542.05542.2 0.152 18-Jul R.ADSVSSSNIK.N sp|Q53F19|NCBP3_HUMAN 1 1006.4931 1.19 76511 5542 2 1006.492102 504.2538 Nuclear cap-binding protein subunit 3 OS=Homo sapiens OX=9606 GN=NCBP3 PE=1 SV=2 5.88 1523.5 - 8.46E+06 - - - -0.9955 - 1.57 0.208 - 189.3 1 2 0 -0.001 10 0 0 0 9.49E+07 7.96E+07 - - - 1.8361 0.9632 221125_WJC_METTL3_EV_vs_WT_F06.05544.05544.2 7.59 18-Aug K.IIR[166.11]PSETAGR[166.11].Y "sp|P19388|RPAB1_HUMAN,tr|A0A087WVZ9|A0A087WVZ9_HUMAN,tr|A0A087WWX0|A0A087WWX0_HUMAN" 3 1118.6311 1.3 76513 5544 2 1118.629374 560.3228 "DNA-directed RNA polymerases I, II, and III subunit RPABC1 OS=Homo sapiens OX=9606 GN=POLR2E PE=1 SV=4" 9.6 1523.7 - 953561 - - - -1.5394 - 1.304 0.037 - 82.8 1 2 0 -0.0017 10 0 0 0 7.17E+07 5.50E+07 - - - 0.0547 0.9994 221125_WJC_METTL3_EV_vs_WT_F06.05552.05552.2 0.00926 14-Oct R.QNEEELSR.L "sp|Q15643|TRIPB_HUMAN,tr|H0YJ97|H0YJ97_HUMAN" 2 1003.4571 1.15 76519 5552 2 1003.454982 502.7358 Thyroid receptor-interacting protein 11 OS=Homo sapiens OX=9606 GN=TRIP11 PE=1 SV=3 4.25 1524.5 - 1.19E+07 - - - -2.0639 - 1.995 0.347 - 658.5 1 2 0 -0.0021 8 0 0 0 5.95E+08 5.19E+08 - - - 3.6862 0.9933 221125_WJC_METTL3_EV_vs_WT_F06.05553.05553.2 9.51E-08 20-Sep D.AC[160.03]MDSEAPGSK[136.11].D "sp|Q86U44|MTA70_HUMAN,tr|H0YFV6|H0YFV6_HUMAN" 2 1159.4729 0 76520 5553 2 1159.472495 580.7437 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 4.37 1524.5 - 2.79E+06 - - - -0.3571 - 1.91 0.571 - 281 1 1 0 -0.0004 11 0 0 0 2.40E+05 6.59E+07 - - - 5.0088 0.875 221125_WJC_METTL3_EV_vs_WT_F06.05555.05555.2 0.19 16-May K.KVHPAVVIR.Q "sp|P62829|RL23_HUMAN,tr|J3QQT9|J3QQT9_HUMAN,tr|J3KT29|J3KT29_HUMAN,tr|J3KTJ3|J3KTJ3_HUMAN,tr|C9JD32|C9JD32_HUMAN" 5 1017.6447 1.13 76522 5555 2 1017.646539 509.8296 60S ribosomal protein L23 OS=Homo sapiens OX=9606 GN=RPL23 PE=1 SV=1 11 1524.7 - 1.20E+06 - - - 1.7737 - 1.204 0.002 - 105.5 3 2 0 0.0018 9 0 0 0 1.70E+07 1.50E+07 - - - -0.6208 0.9863 221125_WJC_METTL3_EV_vs_WT_F06.05559.05559.2 0.398 12-Sep R.RIDQLNR.E "sp|Q16891|MIC60_HUMAN,tr|B9A067|B9A067_HUMAN,tr|C9J406|C9J406_HUMAN,tr|H7C463|H7C463_HUMAN" 4 913.5094 1.35 76524 5559 2 913.508491 457.762 MICOS complex subunit MIC60 OS=Homo sapiens OX=9606 GN=IMMT PE=1 SV=1 9.6 1525.1 - 2.91E+06 - - - -0.9546 - 1.588 0.001 - 248.9 1 2 0 -0.0009 7 0 0 0 3.42E+08 2.53E+08 - - - 0.5135 0.9948 221125_WJC_METTL3_EV_vs_WT_F06.05560.05560.2 0.174 12-Jul K.STENFQR.T "sp|A8K2U0|A2ML1_HUMAN,tr|H0YGG5|H0YGG5_HUMAN" 2 880.4039 2.32 76525 5560 2 880.401 441.2092 Alpha-2-macroglobulin-like protein 1 OS=Homo sapiens OX=9606 GN=A2ML1 PE=1 SV=3 5.72 1525.1 - 2.20E+06 - - - -3.2883 - 1.431 0.304 - 245.5 1 2 0 -0.0029 7 0 0 0 6.15E+07 2.66E+07 - - - 2.421 0.9999 221125_WJC_METTL3_EV_vs_WT_F06.05561.05561.3 0.000169 Oct-36 R.LEEDKPAVER.C sp|Q9Y5J1|UTP18_HUMAN 1 1184.6037 1.91 76526 5561 3 1184.602637 395.8752 U3 small nucleolar RNA-associated protein 18 homolog OS=Homo sapiens OX=9606 GN=UTP18 PE=1 SV=3 4.41 1525.2 - 3.83E+06 - - - -0.9117 - 2.124 0.386 - 111.3 1 2 0 -0.0011 10 0 0 0 3.37E+07 1.76E+07 - - - 5.0432 0.9998 221125_WJC_METTL3_EV_vs_WT_F06.05564.05564.2 1.98E-06 24-Dec K.EESAASGGAAYTK.R "sp|Q9Y2W1|TR150_HUMAN,tr|A0A3B3ITZ9|A0A3B3ITZ9_HUMAN" 2 1240.5572 2.81 76529 5564 2 1240.554901 621.2859 Thyroid hormone receptor-associated protein 3 OS=Homo sapiens OX=9606 GN=THRAP3 PE=1 SV=2 4.53 1525.6 - 1.02E+06 - - - -1.8218 - 2.578 0.523 - 588.2 1 2 0 -0.0023 13 0 0 0 1.60E+09 5.69E+08 - - - 5.3337 0.9702 221125_WJC_METTL3_EV_vs_WT_F06.05566.05566.2 2.51 12-May K.EQSIVEK[136.11].F "sp|Q86U44|MTA70_HUMAN,tr|H0YFV6|H0YFV6_HUMAN" 2 839.448 0.02 76530 5566 2 839.447555 420.7313 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 4.53 1525.8 - 6.18E+08 - - - -0.5277 - 1.271 0.016 - 187 1 2 0 -0.0004 7 0 0 0 2.50E+08 1.13E+10 - - - -0.0811 0.9996 221125_WJC_METTL3_EV_vs_WT_F06.05571.05571.2 0.0152 18-Nov K.IIRPSETAGR.Y "sp|P19388|RPAB1_HUMAN,tr|A0A087WVZ9|A0A087WVZ9_HUMAN,tr|A0A087WWX0|A0A087WWX0_HUMAN" 3 1098.6146 1.3 76534 5571 2 1098.613989 550.3146 "DNA-directed RNA polymerases I, II, and III subunit RPABC1 OS=Homo sapiens OX=9606 GN=POLR2E PE=1 SV=4" 9.6 1526.3 - 2.45E+06 - - - -0.5161 - 2.058 0.315 - 170.8 1 2 0 -0.0006 10 0 0 0 7.17E+07 5.50E+07 - - - 3.382 0.9999 221125_WJC_METTL3_EV_vs_WT_F06.05572.05572.2 1.05E-06 15/24 K.EESAASGGAAYTK[136.11].R "sp|Q9Y2W1|TR150_HUMAN,tr|A0A3B3ITZ9|A0A3B3ITZ9_HUMAN" 2 1248.5714 2.81 76535 5572 2 1248.569937 625.293 Thyroid hormone receptor-associated protein 3 OS=Homo sapiens OX=9606 GN=THRAP3 PE=1 SV=2 4.53 1526.4 - 2.20E+06 - - - -1.1405 - 2.726 0.554 - 1024.2 1 2 0 -0.0014 13 0 0 0 1.60E+09 5.69E+08 - - - 5.7062 0.9999 221125_WJC_METTL3_EV_vs_WT_F06.05573.05573.3 6.56E-05 14/48 R.VHPAMATAAGGC[160.03]R[166.11].S "tr|H7C561|H7C561_HUMAN,tr|H7C0N4|H7C0N4_HUMAN" 2 1307.6102 1.07 76536 5573 3 1307.610349 436.8774 Splicing factor 1 (Fragment) OS=Homo sapiens OX=9606 GN=SF1 PE=1 SV=8 8.23 1526.5 - 1.78E+06 - - - 0.091 - 2.215 0.393 - 174.4 1 2 0 0.0001 13 0 0 0 2.85E+07 2.67E+07 - - - 5.0777 0.991 221125_WJC_METTL3_EV_vs_WT_F06.05574.05574.2 9.04E-05 13/24 D.TTAAPAAAAAPAK.V "sp|Q8NHW5|RLA0L_HUMAN,sp|P05388|RLA0_HUMAN,tr|F8VWS0|F8VWS0_HUMAN,tr|F8W1K8|F8W1K8_HUMAN" 4 1110.6033 0.56 76537 5574 2 1110.602362 556.3089 60S acidic ribosomal protein P0-like OS=Homo sapiens OX=9606 GN=RPLP0P6 PE=5 SV=1 8.41 1526.6 - 1.59E+06 - - - -0.8653 - 2.318 0.472 - 561.3 1 1 0 -0.001 13 0 0 0 1.83E+07 3.28E+07 - - - 4.6846 0.9994 221125_WJC_METTL3_EV_vs_WT_F06.05580.05580.2 0.0898 16-Jul R.LGNDFHTNK.R "sp|P08708|RS17_HUMAN,tr|H0YN73|H0YN73_HUMAN,tr|H3BNC9|H3BNC9_HUMAN,tr|A0A0J9YYC4|A0A0J9YYC4_HUMAN,tr|H0YN88|H0YN88_HUMAN,tr|A0A075B716|A0A075B716_HUMAN" 6 1044.4989 1.2 76541 5580 2 1044.497857 523.2567 40S ribosomal protein S17 OS=Homo sapiens OX=9606 GN=RPS17 PE=1 SV=2 6.74 1527.3 - 1.14E+07 - - - -0.9584 - 1.789 0.306 - 120.3 1 2 0 -0.001 9 0 0 0 6.23E+08 5.21E+08 - - - 2.9836 0.9995 221125_WJC_METTL3_EV_vs_WT_F06.05581.05581.2 0.00205 18-Sep M.PFSNSHNALK[136.11].L "sp|P12277|KCRB_HUMAN,tr|G3V4N7|G3V4N7_HUMAN,tr|G3V2I1|G3V2I1_HUMAN" 3 1121.5709 0.63 76542 5581 2 1121.56942 561.7927 Creatine kinase B-type OS=Homo sapiens OX=9606 GN=CKB PE=1 SV=1 9.18 1527.3 - 3.66E+06 - - - -1.3258 - 1.575 0.402 - 239 1 2 0 -0.0015 10 0 0 0 2.17E+07 3.43E+07 - - - 3.2777 0.996 221125_WJC_METTL3_EV_vs_WT_F06.05586.05586.2 0.265 16-Aug R.GHVELSEAR.L sp|Q96H79|ZCCHL_HUMAN 1 996.4989 1.56 76545 5586 2 996.497723 499.2567 Zinc finger CCCH-type antiviral protein 1-like OS=Homo sapiens OX=9606 GN=ZC3HAV1L PE=1 SV=2 5.4 1527.9 - 5.42E+06 - - - -1.139 - 1.264 0.233 - 217.4 1 2 0 -0.0011 9 0 0 0 1.36E+08 8.73E+07 - - - 1.4394 0.9972 221125_WJC_METTL3_EV_vs_WT_F06.05587.05587.2 0.000657 16-Sep R.MVQEAEK[136.11]YK[136.11].A "sp|P0DMV8|HS71A_HUMAN,sp|P11142|HSP7C_HUMAN,sp|P0DMV9|HS71B_HUMAN,tr|E9PNE6|E9PNE6_HUMAN,tr|A8K7Q2|A8K7Q2_HUMAN,tr|E9PKE3|E9PKE3_HUMAN,tr|E9PM13|E9PM13_HUMAN,tr|E9PS65|E9PS65_HUMAN,tr|V9GZ37|V9GZ37_HUMAN,tr|A0A0G2JIW1|A0A0G2JIW1_HUMAN" 10 1140.582 0.21 76546 5587 2 1140.581002 571.2983 Heat shock 70 kDa protein 1A OS=Homo sapiens OX=9606 GN=HSPA1A PE=1 SV=1 5.9 1528 - 3.65E+06 - - - -0.8715 - 1.742 0.447 - 233.4 1 2 1 -0.001 9 0 0 0 1.03E+07 4.83E+07 - - - 3.948 0.9799 221125_WJC_METTL3_EV_vs_WT_F06.05588.05588.2 0.186 16-Oct Q.QSISDAEQR.G sp|P04264|K2C1_HUMAN 1 1032.4836 0.08 76547 5588 2 1032.482848 517.2491 "Keratin, type II cytoskeletal 1 OS=Homo sapiens OX=9606 GN=KRT1 PE=1 SV=6" 4.37 1528 - 3.18E+06 - - - -0.7303 - 2.078 0.32 - 422.7 1 1 0 -0.0008 9 0 0 0 4.11E+07 5.31E+08 - - - 3.5203 0.9998 221125_WJC_METTL3_EV_vs_WT_F06.05590.05590.2 0.00118 24-Oct R.VHPAMATAAGGC[160.03]R[166.11].S "tr|H7C561|H7C561_HUMAN,tr|H7C0N4|H7C0N4_HUMAN" 2 1307.6102 1.41 76548 5590 2 1307.609398 654.8124 Splicing factor 1 (Fragment) OS=Homo sapiens OX=9606 GN=SF1 PE=1 SV=8 8.23 1528.2 - 636878 - - - -0.6363 - 1.668 0.505 - 215.3 1 2 0 -0.0008 13 0 0 0 3.59E+06 2.55E+06 - - - 4.0838 0.9917 221125_WJC_METTL3_EV_vs_WT_F06.05592.05592.2 0.36 12-Sep R.R[166.11]IDQLNR[166.11].E "sp|Q16891|MIC60_HUMAN,tr|B9A067|B9A067_HUMAN,tr|C9J406|C9J406_HUMAN,tr|H7C463|H7C463_HUMAN" 4 933.5259 1.35 76549 5592 2 933.524668 467.7702 MICOS complex subunit MIC60 OS=Homo sapiens OX=9606 GN=IMMT PE=1 SV=1 9.6 1528.4 - 2.42E+07 - - - -1.3229 - 1.845 0 - 250.6 1 2 0 -0.0012 7 0 0 0 3.42E+08 2.53E+08 - - - 0.9813 0.9846 221125_WJC_METTL3_EV_vs_WT_F06.05594.05594.2 0.263 14-Aug R.LSK[136.11]EEIER[166.11].M "sp|P0DMV8|HS71A_HUMAN,sp|P34931|HS71L_HUMAN,sp|P0DMV9|HS71B_HUMAN,tr|Q53FA3|Q53FA3_HUMAN,tr|V9GZ37|V9GZ37_HUMAN,tr|A0A0G2JIW1|A0A0G2JIW1_HUMAN" 6 1020.557 0.15 76550 5594 2 1020.555647 511.2858 Heat shock 70 kDa protein 1A OS=Homo sapiens OX=9606 GN=HSPA1A PE=1 SV=1 4.79 1528.6 - 2.91E+07 - - - -1.3698 - 1.775 0.22 - 255.1 1 2 1 -0.0014 8 0 0 0 1.58E+09 1.04E+10 - - - 2.396 0.9672 221125_WJC_METTL3_EV_vs_WT_F06.05596.05596.2 0.00475 14-Aug L.GNDFHTNK.R "sp|P08708|RS17_HUMAN,tr|H0YN73|H0YN73_HUMAN,tr|H3BNC9|H3BNC9_HUMAN,tr|A0A0J9YYC4|A0A0J9YYC4_HUMAN,tr|H0YN88|H0YN88_HUMAN,tr|A0A075B716|A0A075B716_HUMAN" 6 931.4148 0.84 76552 5596 2 931.413517 466.7147 40S ribosomal protein S17 OS=Homo sapiens OX=9606 GN=RPS17 PE=1 SV=2 6.74 1528.7 - 1.94E+07 - - - -1.371 - 1.59 0.384 - 241.3 1 1 0 -0.0013 8 0 0 0 2.46E+08 2.92E+08 - - - 3.2754 0.9985 221125_WJC_METTL3_EV_vs_WT_F06.05597.05597.2 0.226 14-Aug K.QASEGPLK.G "sp|P04406|G3P_HUMAN,tr|E7EUT5|E7EUT5_HUMAN" 2 828.4341 0.26 76553 5597 2 828.433791 415.2243 Glyceraldehyde-3-phosphate dehydrogenase OS=Homo sapiens OX=9606 GN=GAPDH PE=1 SV=3 6 1528.8 - 1.74E+07 - - - -0.4116 - 1.449 0.256 - 317.8 1 2 0 -0.0003 8 0 0 0 2.40E+08 9.27E+08 - - - 2.0502 0.9985 221125_WJC_METTL3_EV_vs_WT_F06.05602.05602.2 0.0924 16-Nov R.QHIQDGALR.L "sp|Q13724|MOGS_HUMAN,tr|B8ZZE2|B8ZZE2_HUMAN,tr|A0A3B3IRI7|A0A3B3IRI7_HUMAN,tr|C9JDQ1|C9JDQ1_HUMAN,tr|A0A3B3ITU6|A0A3B3ITU6_HUMAN,tr|A0A3B3ITC1|A0A3B3ITC1_HUMAN" 6 1036.5414 0.71 76558 5602 2 1036.540028 519.278 Mannosyl-oligosaccharide glucosidase OS=Homo sapiens OX=9606 GN=MOGS PE=1 SV=5 6.74 1529.1 - 2.22E+06 - - - -1.3149 - 1.784 0.216 - 466.3 1 2 0 -0.0014 9 0 0 0 2.82E+07 3.95E+07 - - - 2.3106 0.8857 221125_WJC_METTL3_EV_vs_WT_F06.05604.05604.2 0.00364 18-Nov K.SEVAAENHLR.L sp|Q14554|PDIA5_HUMAN 1 1124.5574 0.6 76560 5604 2 1124.54912 563.286 Protein disulfide-isomerase A5 OS=Homo sapiens OX=9606 GN=PDIA5 PE=1 SV=1 5.38 1529.4 - 949558 - - - -7.394 - 1.935 0.168 - 233.7 1 2 0 -0.0083 10 0 0 0 7.12E+06 1.18E+07 - - - 2.1218 0.9213 221125_WJC_METTL3_EV_vs_WT_F06.05608.05608.2 0.278 14-Jul R.VPEEDLK[136.11]R[166.11].T sp|Q99832|TCPH_HUMAN 1 1002.5465 0.32 76562 5608 2 1002.542666 502.2805 T-complex protein 1 subunit eta OS=Homo sapiens OX=9606 GN=CCT7 PE=1 SV=2 4.68 1529.8 - 4.02E+07 - - - -3.8043 - 1.486 0.048 - 161.3 1 2 0 -0.0038 8 0 0 0 4.72E+07 1.46E+08 - - - 0.5889 0.9961 221125_WJC_METTL3_EV_vs_WT_F06.05609.05609.2 0.000186 16-Sep R.DTGNIGQER.V "sp|Q01082|SPTB2_HUMAN,tr|A0A087WUZ3|A0A087WUZ3_HUMAN" 2 988.4574 1.14 76563 5609 2 988.459874 495.236 "Spectrin beta chain, non-erythrocytic 1 OS=Homo sapiens OX=9606 GN=SPTBN1 PE=1 SV=2" 4.37 1529.9 - 7.15E+06 - - - 2.516 - 1.698 0.223 - 399.4 1 2 0 0.0025 9 0 0 0 7.03E+07 6.19E+07 - - - 2.219 0.8264 221125_WJC_METTL3_EV_vs_WT_F06.05611.05611.2 0.00339 12-Jun G.NDFHTNK.R "sp|P08708|RS17_HUMAN,tr|H0YN73|H0YN73_HUMAN,tr|H3BNC9|H3BNC9_HUMAN,tr|A0A0J9YYC4|A0A0J9YYC4_HUMAN,tr|H0YN88|H0YN88_HUMAN,tr|A0A075B716|A0A075B716_HUMAN" 6 874.3933 1.04 76565 5611 2 874.391407 438.2039 40S ribosomal protein S17 OS=Homo sapiens OX=9606 GN=RPS17 PE=1 SV=2 6.74 1530 - 3.69E+06 - - - -2.1992 - 1.315 0.294 - 156.3 1 1 0 -0.0019 7 0 0 0 2.57E+07 2.47E+07 - - - 2.0795 0.9989 221125_WJC_METTL3_EV_vs_WT_F06.05612.05612.2 0.366 16-Oct R.ELQPQQQPR[166.11].T "sp|P55196|AFAD_HUMAN,tr|J3KN01|J3KN01_HUMAN,tr|H0Y948|H0Y948_HUMAN,tr|A0A804HJ20|A0A804HJ20_HUMAN,tr|Q5TIG5|Q5TIG5_HUMAN,tr|A8MQ02|A8MQ02_HUMAN" 6 1132.5864 1.63 76566 5612 2 1132.587205 567.3005 Afadin OS=Homo sapiens OX=9606 GN=AFDN PE=1 SV=3 6.1 1530.1 - 1.66E+06 - - - 0.6746 - 1.658 0.255 - 393.7 1 2 0 0.0008 9 0 0 0 2.55E+07 1.56E+07 - - - 2.387 0.9987 221125_WJC_METTL3_EV_vs_WT_F06.05620.05620.2 0.191 12-Aug K.TYEDLKR.Q sp|Q12874|SF3A3_HUMAN 1 923.4712 3.1 76572 5620 2 923.470683 462.7429 Splicing factor 3A subunit 3 OS=Homo sapiens OX=9606 GN=SF3A3 PE=1 SV=1 5.73 1531 - 2.12E+07 - - - -0.6097 - 1.529 0.243 - 258.4 1 2 0 -0.0006 7 0 0 0 3.11E+08 1.00E+08 - - - 2.181 0.9722 221125_WJC_METTL3_EV_vs_WT_F06.05621.05621.2 0.321 14-Jul R.LSKEEIER[166.11].M "sp|P0DMV8|HS71A_HUMAN,sp|P34931|HS71L_HUMAN,sp|P0DMV9|HS71B_HUMAN,tr|Q53FA3|Q53FA3_HUMAN,tr|V9GZ37|V9GZ37_HUMAN,tr|A0A0G2JIW1|A0A0G2JIW1_HUMAN" 6 1012.5428 - 76573 5621 2 1012.542797 507.2787 Heat shock 70 kDa protein 1A OS=Homo sapiens OX=9606 GN=HSPA1A PE=1 SV=1 4.79 1531 - 6.61E+06 - - - -0.0474 - 1.634 0.146 - 206.4 1 2 1 0 8 0 0 0 - - - - - 1.6003 0.9813 221125_WJC_METTL3_EV_vs_WT_F06.05630.05630.2 0.00352 13/22 L.TALAAQQQAAGK[136.11].E sp|Q96A49|SYAP1_HUMAN 1 1164.6342 2.29 76580 5630 2 1164.632275 583.3244 Synapse-associated protein 1 OS=Homo sapiens OX=9606 GN=SYAP1 PE=1 SV=1 8.41 1531.8 - 2.14E+06 - - - -1.6838 - 2.362 0.394 - 530.3 1 1 0 -0.002 12 0 0 0 3.75E+07 1.64E+07 - - - 4.212 0.9972 221125_WJC_METTL3_EV_vs_WT_F06.05634.05634.2 1.21 12-Sep K.VTAHWHK.G "sp|Q8IUR0|TPPC5_HUMAN,tr|M0QZQ8|M0QZQ8_HUMAN" 2 877.4559 2.81 76584 5634 2 877.455752 439.7352 Trafficking protein particle complex subunit 5 OS=Homo sapiens OX=9606 GN=TRAPPC5 PE=1 SV=1 8.74 1532.4 - 702673 - - - -0.1356 - 1.493 0.163 - 316.4 1 2 0 -0.0001 7 0 0 0 1.86E+07 6.61E+06 - - - 1.5148 0.9998 221125_WJC_METTL3_EV_vs_WT_F06.05640.05640.2 0.0539 16-Dec K.KVEPVPVTK.Q sp|Q86UP2|KTN1_HUMAN 1 995.6015 1.55 76588 5640 2 995.60051 498.808 Kinectin OS=Homo sapiens OX=9606 GN=KTN1 PE=1 SV=1 8.59 1532.9 - 5.08E+06 - - - -1.0265 - 2.558 0.369 - 577 1 2 0 -0.001 9 0 0 0 6.29E+07 4.05E+07 - - - 4.4833 0.9987 221125_WJC_METTL3_EV_vs_WT_F06.05646.05646.2 0.000836 16-Jul K.VETYNDESR.L "sp|P27694|RFA1_HUMAN,tr|I3L4R8|I3L4R8_HUMAN" 2 1111.4782 1.2 76592 5646 2 1111.476449 556.7464 Replication protein A 70 kDa DNA-binding subunit OS=Homo sapiens OX=9606 GN=RPA1 PE=1 SV=2 4.14 1533.5 - 1.59E+07 - - - -1.5592 - 1.52 0.334 - 61.3 2 2 0 -0.0017 9 0 0 0 9.63E+07 8.05E+07 - - - 2.5843 0.9864 221125_WJC_METTL3_EV_vs_WT_F06.05648.05648.2 0.0217 14-Oct R.SVEDLK[136.11]ER[166.11].Y "sp|Q9NPF5|DMAP1_HUMAN,tr|Q5TG39|Q5TG39_HUMAN,tr|Q5TG38|Q5TG38_HUMAN,tr|Q5TG40|Q5TG40_HUMAN" 4 992.5257 1.23 76594 5648 2 992.523223 497.2701 DNA methyltransferase 1-associated protein 1 OS=Homo sapiens OX=9606 GN=DMAP1 PE=1 SV=1 4.68 1533.6 - 5.01E+06 - - - -2.541 - 1.861 0.323 - 322.4 1 2 1 -0.0025 8 0 0 0 5.77E+07 4.68E+07 - - - 3.2991 0.9935 221125_WJC_METTL3_EV_vs_WT_F06.05649.05649.2 0.00683 14-Nov K.IR[166.11]EEYPDR[166.11].L "sp|Q9BVA1|TBB2B_HUMAN,sp|A6NNZ2|TBB8B_HUMAN,sp|P07437|TBB5_HUMAN,sp|Q13885|TBB2A_HUMAN,sp|P68371|TBB4B_HUMAN,sp|Q3ZCM7|TBB8_HUMAN,sp|Q9H4B7|TBB1_HUMAN,tr|Q5ST81|Q5ST81_HUMAN,tr|Q5JP53|Q5JP53_HUMAN,tr|A0A075B736|A0A075B736_HUMAN,tr|Q5SQY0|Q5SQY0_HUMAN" 11 1096.5416 0.8 76595 5649 2 1096.539892 549.2781 Tubulin beta-2B chain OS=Homo sapiens OX=9606 GN=TUBB2B PE=1 SV=1 4.68 1533.8 - 1.86E+06 - - - -1.5695 - 1.908 0.323 - 445.6 1 2 1 -0.0017 8 0 0 0 4.62E+08 5.81E+08 - - - 3.3746 0.9984 221125_WJC_METTL3_EV_vs_WT_F06.05652.05652.2 0.135 16-Sep R.KISVVSATK.G "sp|Q9UKV3|ACINU_HUMAN,tr|S4R3H4|S4R3H4_HUMAN,tr|E7EQT4|E7EQT4_HUMAN,tr|G3V3T3|G3V3T3_HUMAN" 4 931.5702 1.31 76596 5652 2 931.568679 466.7924 Apoptotic chromatin condensation inducer in the nucleus OS=Homo sapiens OX=9606 GN=ACIN1 PE=1 SV=2 10 1534.1 - 4.33E+06 - - - -1.6671 - 1.799 0.229 - 250.8 1 2 0 -0.0016 9 0 0 0 1.35E+08 1.03E+08 - - - 2.4308 0.9927 221125_WJC_METTL3_EV_vs_WT_F06.05653.05653.2 0.137 14-Sep R.TNSPGFQK.K "sp|Q5T8P6|RBM26_HUMAN,tr|A0A087X0H9|A0A087X0H9_HUMAN" 2 877.4294 0.8 76597 5653 2 877.427692 439.722 RNA-binding protein 26 OS=Homo sapiens OX=9606 GN=RBM26 PE=1 SV=3 8.41 1534.2 - 2.88E+06 - - - -1.9249 - 1.594 0.122 - 434.1 1 2 0 -0.0017 8 0 0 0 8.52E+07 1.07E+08 - - - 1.3477 0.98 221125_WJC_METTL3_EV_vs_WT_F06.05657.05657.2 0.0091 18-Oct K.NHPMTPEAVK[136.11].A "sp|P51659|DHB4_HUMAN,tr|A0A2R8Y7L2|A0A2R8Y7L2_HUMAN,tr|A0A2R8YD50|A0A2R8YD50_HUMAN,tr|E7ET17|E7ET17_HUMAN,tr|E7ER27|E7ER27_HUMAN,tr|E7EPL9|E7EPL9_HUMAN,tr|A0A804HKU2|A0A804HKU2_HUMAN,tr|A0A804HIG8|A0A804HIG8_HUMAN,tr|A0A804HK65|A0A804HK65_HUMAN" 9 1130.5634 0.78 76601 5657 2 1130.55858 566.289 Peroxisomal multifunctional enzyme type 2 OS=Homo sapiens OX=9606 GN=HSD17B4 PE=1 SV=3 6.75 1534.6 - 1.37E+06 - - - -4.2448 - 1.532 0.221 - 320.6 1 2 0 -0.0048 10 0 0 0 9.35E+06 1.20E+07 - - - 1.8625 0.9999 221125_WJC_METTL3_EV_vs_WT_F06.05661.05661.2 2.78E-05 20-Oct R.VGSTSENITQK[136.11].V "sp|O00571|DDX3X_HUMAN,sp|O15523|DDX3Y_HUMAN,tr|A0A2R8YFR4|A0A2R8YFR4_HUMAN,tr|A0A2R8YCW1|A0A2R8YCW1_HUMAN,tr|A0A2R8YDH3|A0A2R8YDH3_HUMAN,tr|A0A2R8YDT5|A0A2R8YDT5_HUMAN,tr|A0A2R8Y645|A0A2R8Y645_HUMAN,tr|A0A2R8YF78|A0A2R8YF78_HUMAN,tr|A0A0D9SFB3|A0A0D9SFB3_HUMAN,tr|A0A2R8YFS5|A0A2R8YFS5_HUMAN,tr|A0A0D9SF53|A0A0D9SF53_HUMAN,tr|A0A2R8Y5G6|A0A2R8Y5G6_HUMAN,tr|A0A2R8Y7T2|A0A2R8Y7T2_HUMAN,tr|A0A0D9SG12|A0A0D9SG12_HUMAN,tr|F6S8Q4|F6S8Q4_HUMAN,tr|A0A2U3TZJ9|A0A2U3TZJ9_HUMAN,tr|A0A2R8Y4A4|A0A2R8Y4A4_HUMAN" 17 1170.5972 1.18 76603 5661 2 1170.597049 586.3059 ATP-dependent RNA helicase DDX3X OS=Homo sapiens OX=9606 GN=DDX3X PE=1 SV=3 5.97 1535.1 - 5.66E+06 - - - -0.1128 - 2.34 0.51 - 440.6 1 2 0 -0.0001 11 0 0 0 6.00E+08 5.10E+08 - - - 5.1077 0.9999 221125_WJC_METTL3_EV_vs_WT_F06.05662.05662.2 1.20E-05 20-Sep R.VGSTSENITQK.V "sp|O00571|DDX3X_HUMAN,sp|O15523|DDX3Y_HUMAN,tr|A0A2R8YFR4|A0A2R8YFR4_HUMAN,tr|A0A2R8YCW1|A0A2R8YCW1_HUMAN,tr|A0A2R8YDH3|A0A2R8YDH3_HUMAN,tr|A0A2R8YDT5|A0A2R8YDT5_HUMAN,tr|A0A2R8Y645|A0A2R8Y645_HUMAN,tr|A0A2R8YF78|A0A2R8YF78_HUMAN,tr|A0A0D9SFB3|A0A0D9SFB3_HUMAN,tr|A0A2R8YFS5|A0A2R8YFS5_HUMAN,tr|A0A0D9SF53|A0A0D9SF53_HUMAN,tr|A0A2R8Y5G6|A0A2R8Y5G6_HUMAN,tr|A0A2R8Y7T2|A0A2R8Y7T2_HUMAN,tr|A0A0D9SG12|A0A0D9SG12_HUMAN,tr|F6S8Q4|F6S8Q4_HUMAN,tr|A0A2U3TZJ9|A0A2U3TZJ9_HUMAN,tr|A0A2R8Y4A4|A0A2R8Y4A4_HUMAN" 17 1162.583 1.18 76604 5662 2 1162.581923 582.2988 ATP-dependent RNA helicase DDX3X OS=Homo sapiens OX=9606 GN=DDX3X PE=1 SV=3 5.97 1535.1 - 5.86E+06 - - - -0.91 - 2.34 0.543 - 334.3 1 2 0 -0.0011 11 0 0 0 6.00E+08 5.10E+08 - - - 5.3511 0.9996 221125_WJC_METTL3_EV_vs_WT_F06.05663.05663.2 0.000427 16-Oct R.VEEDIQQQK.A sp|P15924|DESP_HUMAN 1 1115.5459 39.46 76605 5663 2 1115.544763 558.7802 Desmoplakin OS=Homo sapiens OX=9606 GN=DSP PE=1 SV=3 4.14 1535.2 - 4.51E+06 - - - -0.9905 - 1.973 0.351 - 324.6 1 2 0 -0.0011 9 0 0 0 4.92E+07 1.25E+06 - - - 3.5991 0.82 221125_WJC_METTL3_EV_vs_WT_F06.05665.05665.2 0.00774 12-Aug V.TIVHHVK.E "sp|Q9Y2W1|TR150_HUMAN,tr|A0A3B3ITZ9|A0A3B3ITZ9_HUMAN" 2 832.4919 2.73 76607 5665 2 832.493607 417.2532 Thyroid hormone receptor-associated protein 3 OS=Homo sapiens OX=9606 GN=THRAP3 PE=1 SV=2 8.47 1535.2 - 2.57E+06 - - - 2.024 - 1.246 0.306 - 182.9 1 1 0 0.0017 7 0 0 0 2.69E+07 9.84E+06 - - - 1.9975 0.9817 221125_WJC_METTL3_EV_vs_WT_F06.05667.05667.2 0.278 20-Sep K.LLETTEEDKQK.N "sp|Q7L0Y3|TM10C_HUMAN,tr|C9JVB6|C9JVB6_HUMAN" 2 1332.6773 0.52 76609 5667 2 1332.68082 667.3459 tRNA methyltransferase 10 homolog C OS=Homo sapiens OX=9606 GN=TRMT10C PE=1 SV=2 4.41 1535.5 - 617032 - - - 2.6593 - 1.731 0.35 - 138.1 1 2 1 0.0035 11 0 0 0 4.30E+06 8.27E+06 - - - 3.1093 0.9996 221125_WJC_METTL3_EV_vs_WT_F06.05670.05670.2 0.0021 14-Sep R.TNSPGFQK[136.11].K "sp|Q5T8P6|RBM26_HUMAN,tr|A0A087X0H9|A0A087X0H9_HUMAN" 2 885.4436 0.81 76610 5670 2 885.442402 443.7291 RNA-binding protein 26 OS=Homo sapiens OX=9606 GN=RBM26 PE=1 SV=3 8.41 1535.9 - 8.76E+06 - - - -1.3315 - 1.82 0.374 - 450.4 1 2 0 -0.0012 8 0 0 0 8.39E+07 1.04E+08 - - - 3.6091 0.9999 221125_WJC_METTL3_EV_vs_WT_F06.05671.05671.2 0.003 16-Oct R.FDSDAASQR.M "sp|P04439|HLAA_HUMAN,tr|A0A140T941|A0A140T941_HUMAN,tr|A0A1W2PQS8|A0A1W2PQS8_HUMAN,tr|A0A140T8W8|A0A140T8W8_HUMAN,tr|Q9GJ45|Q9GJ45_HUMAN,tr|Q53Z42|Q53Z42_HUMAN,tr|Q5RJ27|Q5RJ27_HUMAN,tr|Q5SRN5|Q5SRN5_HUMAN,tr|A0A1W2PS24|A0A1W2PS24_HUMAN,tr|A0A140T955|A0A140T955_HUMAN,tr|A0A0G2JPD3|A0A0G2JPD3_HUMAN,tr|A0A140T913|A0A140T913_HUMAN,tr|A0A1W2PPQ2|A0A1W2PPQ2_HUMAN,tr|Q5SPM2|Q5SPM2_HUMAN,tr|A0A140T8Y4|A0A140T8Y4_HUMAN,tr|A0A140T975|A0A140T975_HUMAN,tr|A0A140T933|A0A140T933_HUMAN,tr|A0A1W2PRT9|A0A1W2PRT9_HUMAN,tr|A0A1W2PPF8|A0A1W2PPF8_HUMAN,tr|Q5SRN7|Q5SRN7_HUMAN,tr|A0A1W2PR61|A0A1W2PR61_HUMAN,tr|A0A140T9I0|A0A140T9I0_HUMAN,tr|A0A140T9X5|A0A140T9X5_HUMAN,tr|A0A1W2PS39|A0A1W2PS39_HUMAN,tr|A0A140T9Z6|A0A140T9Z6_HUMAN,tr|B0UXQ0|B0UXQ0_HUMAN" 26 995.4308 1.56 76611 5671 2 995.430352 498.7227 "HLA class I histocompatibility antigen, A alpha chain OS=Homo sapiens OX=9606 GN=HLA-A PE=1 SV=2" 4.21 1536 - 2.70E+06 - - - -0.4882 - 2.124 0.465 - 321.7 1 2 0 -0.0005 9 0 0 0 3.08E+07 1.98E+07 - - - 4.6547 0.9963 221125_WJC_METTL3_EV_vs_WT_F06.05677.05677.2 0.00866 16-Aug K.LK[136.11]DELASTK[136.11].Q sp|P51572|BAP31_HUMAN 1 1019.5834 1.23 76615 5677 2 1019.583284 510.799 B-cell receptor-associated protein 31 OS=Homo sapiens OX=9606 GN=BCAP31 PE=1 SV=3 6.07 1536.7 - 2.47E+07 - - - -0.0902 - 1.662 0.399 - 143.6 1 2 1 -0.0001 9 0 0 0 2.02E+08 1.65E+08 - - - 3.4577 0.998 221125_WJC_METTL3_EV_vs_WT_F06.05679.05679.2 0.667 14-Jul R.EATEQEIR.S "sp|Q9BWF3|RBM4_HUMAN,sp|Q9BQ04|RBM4B_HUMAN,tr|E9PM61|E9PM61_HUMAN,tr|D6R9K7|D6R9K7_HUMAN,tr|J3QRR5|J3QRR5_HUMAN,tr|E9PB51|E9PB51_HUMAN,tr|U3KQD5|U3KQD5_HUMAN,tr|E9PLB0|E9PLB0_HUMAN" 8 974.4669 1.36 76617 5679 2 974.466622 488.2407 RNA-binding protein 4 OS=Homo sapiens OX=9606 GN=RBM4 PE=1 SV=1 4.25 1536.8 - 8.68E+06 - - - -0.274 - 1.503 0.208 - 337.7 1 2 0 -0.0003 8 0 0 0 8.09E+07 5.94E+07 - - - 1.8061 0.9995 221125_WJC_METTL3_EV_vs_WT_F06.05680.05680.2 0.00124 16-Dec R.SVVYQQSSK.E "sp|Q14694|UBP10_HUMAN,tr|H3BNA1|H3BNA1_HUMAN" 2 1024.5189 0.89 76618 5680 2 1024.518019 513.2667 Ubiquitin carboxyl-terminal hydrolase 10 OS=Homo sapiens OX=9606 GN=USP10 PE=1 SV=2 8.31 1536.8 - 5.51E+06 - - - -0.8843 - 1.654 0.351 - 439.9 1 2 0 -0.0009 9 0 0 0 7.59E+07 8.50E+07 - - - 3.089 0.9999 221125_WJC_METTL3_EV_vs_WT_F06.05681.05681.2 1.31E-05 18-Oct K.VDDSSGSIGR.R "sp|P41250|GARS_HUMAN,tr|A0A6Q8PGI6|A0A6Q8PGI6_HUMAN,tr|A0A6Q8PGA8|A0A6Q8PGA8_HUMAN,tr|A0A6Q8PGW4|A0A6Q8PGW4_HUMAN,tr|A0A6Q8PGZ8|A0A6Q8PGZ8_HUMAN,tr|A0A6Q8PHH9|A0A6Q8PHH9_HUMAN" 6 991.4571 1.55 76619 5681 2 991.456079 496.7358 Glycine--tRNA ligase OS=Homo sapiens OX=9606 GN=GARS1 PE=1 SV=3 4.21 1536.9 - 3.59E+06 - - - -0.9824 - 2.275 0.56 - 327.6 1 2 0 -0.001 10 0 0 0 1.58E+08 1.02E+08 - - - 5.4713 0.9972 221125_WJC_METTL3_EV_vs_WT_F06.05683.05683.2 0.0553 16-Sep K.IQNGAQGIR[166.11].F "sp|P31943|HNRH1_HUMAN,tr|E7EQJ0|E7EQJ0_HUMAN,tr|D6RIH9|D6RIH9_HUMAN,tr|D6RJ04|D6RJ04_HUMAN,tr|D6RFM3|D6RFM3_HUMAN,tr|E9PCY7|E9PCY7_HUMAN,tr|D6RIT2|D6RIT2_HUMAN,tr|D6R9T0|D6R9T0_HUMAN,tr|D6RIU0|D6RIU0_HUMAN,tr|D6RAM1|D6RAM1_HUMAN,tr|D6RBM0|D6RBM0_HUMAN,tr|G8JLB6|G8JLB6_HUMAN,tr|D6RF17|D6RF17_HUMAN,tr|D6RDL0|D6RDL0_HUMAN,tr|D6RDU3|D6RDU3_HUMAN,tr|E7EN40|E7EN40_HUMAN" 16 965.5282 0.02 76621 5683 2 965.528238 483.7714 Heterogeneous nuclear ribonucleoprotein H OS=Homo sapiens OX=9606 GN=HNRNPH1 PE=1 SV=4 9.75 1536.9 - 3.05E+06 - - - 0.0414 - 1.819 0.101 - 269.9 1 2 0 0 9 0 0 0 3.75E+05 2.08E+07 - - - 1.5178 0.9992 221125_WJC_METTL3_EV_vs_WT_F06.05695.05695.2 0.0725 16-Oct R.KISVVSATK.G "sp|Q9UKV3|ACINU_HUMAN,tr|S4R3H4|S4R3H4_HUMAN,tr|E7EQT4|E7EQT4_HUMAN,tr|G3V3T3|G3V3T3_HUMAN" 4 931.5702 1.31 76631 5695 2 931.569733 466.7924 Apoptotic chromatin condensation inducer in the nucleus OS=Homo sapiens OX=9606 GN=ACIN1 PE=1 SV=2 10 1538.2 - 9.92E+06 - - - -0.5357 - 1.647 0.28 - 364 1 2 0 -0.0005 9 0 0 0 1.35E+08 1.03E+08 - - - 2.5524 0.9998 221125_WJC_METTL3_EV_vs_WT_F06.05696.05696.2 0.00233 18-Aug R.GSGSDDTELR.Y sp|Q13948|CASP_HUMAN 1 1035.4469 1.35 76632 5696 2 1035.445634 518.7307 Protein CASP OS=Homo sapiens OX=9606 GN=CUX1 PE=1 SV=2 4.03 1538.3 - 4.05E+06 - - - -1.2053 - 1.924 0.523 - 307.7 1 2 0 -0.0012 10 0 0 0 3.26E+07 2.41E+07 - - - 4.7301 0.9993 221125_WJC_METTL3_EV_vs_WT_F06.05697.05697.2 0.0146 14-Sep K.RIAQQLER.E "sp|Q96FZ7|CHMP6_HUMAN,tr|I3L4A1|I3L4A1_HUMAN" 2 1012.5778 1.16 76633 5697 2 1012.576726 507.2962 Charged multivesicular body protein 6 OS=Homo sapiens OX=9606 GN=CHMP6 PE=1 SV=3 9.6 1538.3 - 3.57E+06 - - - -1.0379 - 2.015 0.233 - 163 1 2 0 -0.001 8 0 0 0 4.27E+07 3.68E+07 - - - 2.8746 0.9999 221125_WJC_METTL3_EV_vs_WT_F06.05699.05699.2 0.000661 18-Nov R.GSGSDDTELR[166.11].Y sp|Q13948|CASP_HUMAN 1 1045.4552 1.35 76635 5699 2 1045.45543 523.7349 Protein CASP OS=Homo sapiens OX=9606 GN=CUX1 PE=1 SV=2 4.03 1538.4 - 3.12E+06 - - - 0.2659 - 2.273 0.488 - 584 1 2 0 0.0003 10 0 0 0 3.26E+07 2.41E+07 - - - 4.9372 0.9992 221125_WJC_METTL3_EV_vs_WT_F06.05701.05701.2 0.00707 12-Jul K.KQDAFYK.E "sp|Q9NX63|MIC19_HUMAN,tr|F8WAR4|F8WAR4_HUMAN,tr|C9JRZ6|C9JRZ6_HUMAN" 3 898.4549 1.49 76637 5701 2 898.453978 450.2347 MICOS complex subunit MIC19 OS=Homo sapiens OX=9606 GN=CHCHD3 PE=1 SV=1 8.5 1538.5 - 2.37E+06 - - - -0.9906 - 1.435 0.351 - 179 1 2 0 -0.0009 7 0 0 0 3.68E+08 2.47E+08 - - - 2.7776 0.9987 221125_WJC_METTL3_EV_vs_WT_F06.05704.05704.2 5.46E-05 20-Oct K.APQEVEEDDGR.S "sp|Q9Y6A5|TACC3_HUMAN,tr|H0Y8F2|H0Y8F2_HUMAN,tr|A0A494C117|A0A494C117_HUMAN,tr|A0A494BZT8|A0A494BZT8_HUMAN" 4 1243.5317 2.33 76640 5704 2 1243.527309 622.7731 Transforming acidic coiled-coil-containing protein 3 OS=Homo sapiens OX=9606 GN=TACC3 PE=1 SV=1 3.83 1538.9 - 1.24E+06 - - - -3.5102 - 1.768 0.48 - 332.9 1 2 0 -0.0044 11 0 0 0 8.83E+06 3.80E+06 - - - 4.1265 1 221125_WJC_METTL3_EV_vs_WT_F06.05707.05707.2 7.59E-07 18-Nov K.VDDSSGSIGR[166.11].R "sp|P41250|GARS_HUMAN,tr|A0A6Q8PGI6|A0A6Q8PGI6_HUMAN,tr|A0A6Q8PGA8|A0A6Q8PGA8_HUMAN,tr|A0A6Q8PGW4|A0A6Q8PGW4_HUMAN,tr|A0A6Q8PGZ8|A0A6Q8PGZ8_HUMAN,tr|A0A6Q8PHH9|A0A6Q8PHH9_HUMAN" 6 1001.4653 1.55 76641 5707 2 1001.463936 501.7399 Glycine--tRNA ligase OS=Homo sapiens OX=9606 GN=GARS1 PE=1 SV=3 4.21 1539.3 - 1.49E+07 - - - -1.385 - 2.401 0.594 - 411.3 1 2 0 -0.0014 10 0 0 0 1.58E+08 1.02E+08 - - - 5.8727 0.9985 221125_WJC_METTL3_EV_vs_WT_F06.05710.05710.2 0.0103 16-Aug K.DSETGENIR[166.11].Q "sp|P38646|GRP75_HUMAN,tr|A0A7I2V2S7|A0A7I2V2S7_HUMAN,tr|A0A7I2V2G2|A0A7I2V2G2_HUMAN,tr|A0A7I2V3F7|A0A7I2V3F7_HUMAN,tr|A0A7I2YQB2|A0A7I2YQB2_HUMAN,tr|D6RCD7|D6RCD7_HUMAN" 6 1029.4602 0.5 76644 5710 2 1029.457941 515.7374 "Stress-70 protein, mitochondrial OS=Homo sapiens OX=9606 GN=HSPA9 PE=1 SV=2" 4.14 1539.4 - 4.39E+06 - - - -2.2303 - 1.649 0.323 - 315.3 1 2 0 -0.0023 9 0 0 0 3.28E+08 6.53E+08 - - - 2.873 0.9407 221125_WJC_METTL3_EV_vs_WT_F06.05711.05711.2 0.0417 12-Aug L.R[166.11]EEYPDR[166.11].L "sp|Q9BVA1|TBB2B_HUMAN,sp|A6NNZ2|TBB8B_HUMAN,sp|P07437|TBB5_HUMAN,sp|Q13509|TBB3_HUMAN,sp|Q13885|TBB2A_HUMAN,sp|P68371|TBB4B_HUMAN,sp|Q3ZCM7|TBB8_HUMAN,sp|Q9H4B7|TBB1_HUMAN,tr|A0A0B4J269|A0A0B4J269_HUMAN,tr|Q5ST81|Q5ST81_HUMAN,tr|Q5JP53|Q5JP53_HUMAN,tr|A0A075B736|A0A075B736_HUMAN,tr|G3V2A3|G3V2A3_HUMAN,tr|Q5SQY0|Q5SQY0_HUMAN" 14 983.4575 0.87 76645 5711 2 983.457419 492.7361 Tubulin beta-2B chain OS=Homo sapiens OX=9606 GN=TUBB2B PE=1 SV=1 4.68 1539.5 - 2.43E+06 - - - -0.1322 - 1.436 0.289 - 187 1 1 0 -0.0001 7 0 0 0 3.02E+07 3.49E+07 - - - 2.3221 0.9996 221125_WJC_METTL3_EV_vs_WT_F06.05713.05713.2 0.326 13/16 R.R[166.11]LPPQQIEK[136.11].N "sp|P47756|CAPZB_HUMAN,tr|B1AK87|B1AK87_HUMAN,tr|B1AK88|B1AK88_HUMAN,tr|B1AK85|B1AK85_HUMAN,tr|A0A6I8PIN8|A0A6I8PIN8_HUMAN" 5 1125.6625 1.03 76647 5713 2 1125.662317 563.8385 F-actin-capping protein subunit beta OS=Homo sapiens OX=9606 GN=CAPZB PE=1 SV=4 8.75 1539.7 - 2.01E+06 - - - -0.1741 - 2.346 0.235 - 701.4 1 2 0 -0.0002 9 0 0 0 2.41E+07 2.34E+07 - - - 3.2436 0.9989 221125_WJC_METTL3_EV_vs_WT_F06.05719.05719.2 0.276 16-Aug R.K[136.11]LLEGEESR[166.11].L "sp|P08670|VIME_HUMAN,sp|P17661|DESM_HUMAN,sp|P05787|K2C8_HUMAN,sp|P41219|PERI_HUMAN,sp|P08729|K2C7_HUMAN,tr|H7C5W5|H7C5W5_HUMAN,tr|B0YJC5|B0YJC5_HUMAN,tr|B0YJC4|B0YJC4_HUMAN" 8 1077.5785 2.02 76651 5719 2 1077.576815 539.7965 Vimentin OS=Homo sapiens OX=9606 GN=VIM PE=1 SV=4 4.79 1540.5 - 6.46E+07 - - - -1.5711 - 1.741 0.282 - 246.5 1 2 0 -0.0017 9 0 0 0 2.05E+09 1.01E+09 - - - 2.7274 0.9989 221125_WJC_METTL3_EV_vs_WT_F06.05720.05720.2 0.000911 16-Aug K.DSETGENIR.Q "sp|P38646|GRP75_HUMAN,tr|A0A7I2V2S7|A0A7I2V2S7_HUMAN,tr|A0A7I2V2G2|A0A7I2V2G2_HUMAN,tr|A0A7I2V3F7|A0A7I2V3F7_HUMAN,tr|A0A7I2YQB2|A0A7I2YQB2_HUMAN,tr|D6RCD7|D6RCD7_HUMAN" 6 1019.452 0.5 76652 5720 2 1019.449751 510.7333 "Stress-70 protein, mitochondrial OS=Homo sapiens OX=9606 GN=HSPA9 PE=1 SV=2" 4.14 1540.6 - 6.82E+06 - - - -2.1737 - 1.558 0.377 - 321.9 1 2 0 -0.0022 9 0 0 0 3.28E+08 6.53E+08 - - - 3.1076 0.9995 221125_WJC_METTL3_EV_vs_WT_F06.05721.05721.2 0.12 16-Oct R.NQELEAENR.L sp|Q13948|CASP_HUMAN 1 1101.5051 0.56 76653 5721 2 1101.502812 551.7598 Protein CASP OS=Homo sapiens OX=9606 GN=CUX1 PE=1 SV=2 4.25 1540.6 - 3.70E+06 - - - -2.0454 - 1.995 0.398 - 437.9 1 2 0 -0.0023 9 0 0 0 4.33E+07 7.70E+07 - - - 3.978 0.9995 221125_WJC_METTL3_EV_vs_WT_F06.05727.05727.2 0.334 16-Sep R.KLLEGEESR.L "sp|P08670|VIME_HUMAN,sp|P17661|DESM_HUMAN,sp|P05787|K2C8_HUMAN,sp|P41219|PERI_HUMAN,sp|P08729|K2C7_HUMAN,tr|H7C5W5|H7C5W5_HUMAN,tr|B0YJC5|B0YJC5_HUMAN,tr|B0YJC4|B0YJC4_HUMAN" 8 1059.556 1.52 76657 5727 2 1059.554946 530.7853 Vimentin OS=Homo sapiens OX=9606 GN=VIM PE=1 SV=4 4.79 1541.3 - 1.56E+08 - - - -1.0306 - 2.025 0.277 - 327.7 1 2 0 -0.0011 9 0 0 0 2.06E+09 1.35E+09 - - - 3.1278 0.9872 221125_WJC_METTL3_EV_vs_WT_F06.05730.05730.2 1.04 12-Jul K.K[136.11]QDAFYK[136.11].E "sp|Q9NX63|MIC19_HUMAN,tr|F8WAR4|F8WAR4_HUMAN,tr|C9JRZ6|C9JRZ6_HUMAN" 3 914.4833 1.49 76660 5730 2 914.481992 458.2489 MICOS complex subunit MIC19 OS=Homo sapiens OX=9606 GN=CHCHD3 PE=1 SV=1 8.5 1541.4 - 1.69E+07 - - - -1.3953 - 1.154 0.164 - 184.1 1 2 0 -0.0013 7 0 0 0 3.68E+08 2.47E+08 - - - 0.7057 0.9978 221125_WJC_METTL3_EV_vs_WT_F06.05731.05731.2 0.831 12-Aug K.K[136.11]QLDSLR[166.11].E "sp|Q86U44|MTA70_HUMAN,tr|B4E349|B4E349_HUMAN,tr|F5H6D8|F5H6D8_HUMAN,tr|B4DTN4|B4DTN4_HUMAN" 4 876.5148 0.01 76661 5731 2 876.513937 439.2647 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 8.75 1541.5 - 1.37E+07 - - - -0.9686 - 1.746 0.141 - 294.9 1 2 0 -0.0008 7 0 0 0 3.81E+08 3.09E+10 - - - 1.8481 0.9977 221125_WJC_METTL3_EV_vs_WT_F06.05738.05738.2 0.0113 16-Jul K.SETSGPQIK.E "sp|Q9Y266|NUDC_HUMAN,tr|A0A0A0MSS4|A0A0A0MSS4_HUMAN,tr|A0A0A0MSU9|A0A0A0MSU9_HUMAN" 3 945.4767 1.77 76667 5738 2 945.474997 473.7456 Nuclear migration protein nudC OS=Homo sapiens OX=9606 GN=NUDC PE=1 SV=1 5.72 1542.1 - 1.72E+07 - - - -1.8276 - 1.451 0.284 - 208.9 1 2 0 -0.0017 9 0 0 0 1.76E+09 9.97E+08 - - - 2.215 0.9999 221125_WJC_METTL3_EV_vs_WT_F06.05740.05740.2 2.14E-05 14-Sep R.YDDYSSSR.D "sp|Q96E39|RMXL1_HUMAN,sp|P38159|RBMX_HUMAN,tr|H3BUY5|H3BUY5_HUMAN" 3 991.3883 1.42 76668 5740 2 991.388126 496.7014 "RNA binding motif protein, X-linked-like-1 OS=Homo sapiens OX=9606 GN=RBMXL1 PE=1 SV=1" 4.21 1542.3 - 1.94E+07 - - - -0.1795 - 1.691 0.549 - 247.9 1 2 0 -0.0002 8 0 0 0 1.77E+09 1.25E+09 - - - 4.6802 0.9999 221125_WJC_METTL3_EV_vs_WT_F06.05741.05741.2 1.43E-05 14-Aug R.YDDYSSSR[166.11].D "sp|Q96E39|RMXL1_HUMAN,sp|P38159|RBMX_HUMAN,tr|H3BUY5|H3BUY5_HUMAN" 3 1001.3966 1.42 76669 5741 2 1001.39496 501.7056 "RNA binding motif protein, X-linked-like-1 OS=Homo sapiens OX=9606 GN=RBMXL1 PE=1 SV=1" 4.21 1542.4 - 1.53E+07 - - - -1.6117 - 1.876 0.621 - 199.9 1 2 0 -0.0016 8 0 0 0 1.77E+09 1.25E+09 - - - 5.5247 0.9994 221125_WJC_METTL3_EV_vs_WT_F06.05742.05742.2 5.71E-05 16-Oct K.C[160.03]PEPC[160.03]PPPK.C "sp|P22531|SPR2E_HUMAN,sp|P35326|SPR2A_HUMAN,sp|Q96RM1|SPR2F_HUMAN,sp|P22532|SPR2D_HUMAN,sp|P35325|SPR2B_HUMAN,sp|Q9BYE4|SPR2G_HUMAN" 6 1080.4732 309.25 76670 5742 2 1080.469818 541.2439 Small proline-rich protein 2E OS=Homo sapiens OX=9606 GN=SPRR2E PE=2 SV=2 5.99 1542.4 - 4.35E+07 - - - -3.1644 - 2.017 0.534 - 430.5 1 2 0 -0.0034 9 0 0 0 9.07E+08 2.93E+06 - - - 5.0138 0.9807 221125_WJC_METTL3_EV_vs_WT_F06.05743.05743.3 0.136 13/44 K.LVDQSGPPHEPK.F "sp|P55265|DSRAD_HUMAN,tr|A0A3B3IRQ9|A0A3B3IRQ9_HUMAN,tr|A0A3B3ISU1|A0A3B3ISU1_HUMAN,tr|A0A7P0Z4K3|A0A7P0Z4K3_HUMAN,tr|A0A3B3ISX1|A0A3B3ISX1_HUMAN,tr|A0A7P0Z4F9|A0A7P0Z4F9_HUMAN" 6 1302.6568 1.19 76671 5743 3 1302.653409 435.2262 Double-stranded RNA-specific adenosine deaminase OS=Homo sapiens OX=9606 GN=ADAR PE=1 SV=4 5.32 1542.4 - 4.24E+06 - - - -2.6147 - 1.763 0.172 - 187.9 1 2 0 -0.0034 12 0 0 0 1.41E+08 1.18E+08 - - - 2.0284 0.9999 221125_WJC_METTL3_EV_vs_WT_F06.05748.05748.2 9.14E-10 22-Dec R.QGSPVAAGAPAK.Q sp|Q9NZI8|IF2B1_HUMAN 1 1052.5615 13.78 76674 5748 2 1052.560752 527.288 Insulin-like growth factor 2 mRNA-binding protein 1 OS=Homo sapiens OX=9606 GN=IGF2BP1 PE=1 SV=2 8.75 1543 - 3.84E+07 - - - -0.6707 - 2.787 0.469 - 561.4 1 2 0 -0.0007 12 0 0 0 6.62E+08 4.81E+07 - - - 5.2017 0.9997 221125_WJC_METTL3_EV_vs_WT_F06.05750.05750.2 0.00171 14-Nov R.KIVAEYEK.T "sp|O75410|TACC1_HUMAN,sp|O95359|TACC2_HUMAN,tr|E7EVI4|E7EVI4_HUMAN,tr|B4E3H6|B4E3H6_HUMAN,tr|Q4VXL8|Q4VXL8_HUMAN,tr|H0YAY0|H0YAY0_HUMAN,tr|Q4VXL4|Q4VXL4_HUMAN,tr|E7EMZ9|E7EMZ9_HUMAN,tr|H0Y9C3|H0Y9C3_HUMAN,tr|A0A0U1RRM9|A0A0U1RRM9_HUMAN,tr|E9PBC6|E9PBC6_HUMAN,tr|H0YBT8|H0YBT8_HUMAN,tr|E7ET87|E7ET87_HUMAN,tr|D6RAA5|D6RAA5_HUMAN" 14 978.5386 1.07 76676 5750 2 978.538371 490.2766 Transforming acidic coiled-coil-containing protein 1 OS=Homo sapiens OX=9606 GN=TACC1 PE=1 SV=2 6.14 1543.1 - 6.86E+06 - - - -0.231 - 2.06 0.34 - 469.6 1 2 0 -0.0002 8 0 0 0 8.22E+07 7.67E+07 - - - 3.7318 0.9966 221125_WJC_METTL3_EV_vs_WT_F06.05758.05758.2 1.92 12-Jul K.KQLDSLR[166.11].E "sp|Q86U44|MTA70_HUMAN,tr|B4E349|B4E349_HUMAN,tr|F5H6D8|F5H6D8_HUMAN,tr|B4DTN4|B4DTN4_HUMAN" 4 868.5006 - 76682 5758 2 868.499292 435.2576 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 8.75 1543.8 - 1.53E+07 - - - -1.4899 - 1.638 0.151 - 244.4 1 2 0 -0.0013 7 0 0 0 - - - - - 1.7195 0.9993 221125_WJC_METTL3_EV_vs_WT_F06.05759.05759.2 0.00161 16-Oct R.HGVESTLER[166.11].S "sp|Q04637|IF4G1_HUMAN,tr|E7EUU4|E7EUU4_HUMAN,tr|E9PGM1|E9PGM1_HUMAN,tr|E7EX73|E7EX73_HUMAN,tr|A0A7I2Y1C3|A0A7I2Y1C3_HUMAN" 5 1036.5177 0.43 76683 5759 2 1036.51553 519.2661 Eukaryotic translation initiation factor 4 gamma 1 OS=Homo sapiens OX=9606 GN=EIF4G1 PE=1 SV=4 5.4 1543.8 - 5.42E+06 - - - -2.0868 - 1.833 0.383 - 273.2 1 2 0 -0.0022 9 0 0 0 6.62E+07 1.55E+08 - - - 3.6222 0.8414 221125_WJC_METTL3_EV_vs_WT_F06.05761.05761.2 1.03E-05 14/24 A.LTQSVGGDSSADR[166.11].L "sp|Q86U44|MTA70_HUMAN,tr|H0YFV6|H0YFV6_HUMAN" 2 1301.6087 0.001 76685 5761 2 1301.601086 651.8116 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 4.21 1544 - 1.84E+06 - - - -5.8435 - 2.32 0.578 - 600 1 1 0 -0.0076 13 0 0 0 0.00E+00 2.39E+07 - - - 5.4676 0.9995 221125_WJC_METTL3_EV_vs_WT_F06.05764.05764.2 0.000259 18-Oct R.ELEVQHPAAK[136.11].M "sp|P50990|TCPQ_HUMAN,tr|H7C4C8|H7C4C8_HUMAN" 2 1128.6019 0.73 76686 5764 2 1128.602525 565.3082 T-complex protein 1 subunit theta OS=Homo sapiens OX=9606 GN=CCT8 PE=1 SV=4 5.4 1544.4 - 4.19E+06 - - - 0.5777 - 1.707 0.343 - 396.8 1 2 0 0.0007 10 0 0 0 5.22E+08 7.16E+08 - - - 3.0668 0.9998 221125_WJC_METTL3_EV_vs_WT_F06.05765.05765.2 5.39E-07 13/22 K.LVDQSGPPHEPK[136.11].F "sp|P55265|DSRAD_HUMAN,tr|A0A3B3IRQ9|A0A3B3IRQ9_HUMAN,tr|A0A3B3ISU1|A0A3B3ISU1_HUMAN,tr|A0A7P0Z4K3|A0A7P0Z4K3_HUMAN,tr|A0A3B3ISX1|A0A3B3ISX1_HUMAN,tr|A0A7P0Z4F9|A0A7P0Z4F9_HUMAN" 6 1310.671 0.48 76687 5765 2 1310.668654 656.3428 Double-stranded RNA-specific adenosine deaminase OS=Homo sapiens OX=9606 GN=ADAR PE=1 SV=4 5.32 1544.6 - 973939 - - - -1.8014 - 2.214 0.535 - 472.2 1 2 0 -0.0024 12 0 0 0 5.15E+06 1.08E+07 - - - 5.083 0.9939 221125_WJC_METTL3_EV_vs_WT_F06.05767.05767.2 0.227 14-Aug K.SVLADQGK.S "sp|Q9NYF8|BCLF1_HUMAN,tr|E9PKI6|E9PKI6_HUMAN,tr|A0A1W2PQ43|A0A1W2PQ43_HUMAN,tr|E9PK91|E9PK91_HUMAN,tr|E9PK09|E9PK09_HUMAN,tr|E9PQN2|E9PQN2_HUMAN" 6 816.4341 1.28 76689 5767 2 816.431972 409.2243 Bcl-2-associated transcription factor 1 OS=Homo sapiens OX=9606 GN=BCLAF1 PE=1 SV=2 5.55 1544.7 - 5.15E+06 - - - -2.6457 - 1.351 0.262 - 210.8 1 2 0 -0.0022 8 0 0 0 8.72E+07 6.80E+07 - - - 1.8828 0.977 221125_WJC_METTL3_EV_vs_WT_F06.05769.05769.2 0.0395 18-Aug K.INPDEREEMK.V sp|P48507|GSH0_HUMAN 1 1259.5816 10.82 76691 5769 2 1259.578809 630.7981 Glutamate--cysteine ligase regulatory subunit OS=Homo sapiens OX=9606 GN=GCLM PE=1 SV=1 4.41 1544.8 - 749276 - - - -2.2166 - 1.544 0.309 - 205.1 1 2 1 -0.0028 10 0 0 0 7.36E+06 6.80E+05 - - - 2.5349 0.9928 221125_WJC_METTL3_EV_vs_WT_F06.05773.05773.2 0.0699 14-Jul R.RAFGSGYR.R "sp|P23588|IF4B_HUMAN,tr|E7EX17|E7EX17_HUMAN,tr|F8VX11|F8VX11_HUMAN,tr|F8VP89|F8VP89_HUMAN" 4 912.4566 2.49 76693 5773 2 912.454283 457.2356 Eukaryotic translation initiation factor 4B OS=Homo sapiens OX=9606 GN=EIF4B PE=1 SV=2 10.84 1545.3 - 6.13E+06 - - - -2.5382 - 1.344 0.238 - 109.5 1 2 0 -0.0023 8 0 0 0 6.68E+07 2.68E+07 - - - 1.6898 0.9999 221125_WJC_METTL3_EV_vs_WT_F06.05774.05774.2 1.46E-05 13/18 R.NIIHGSDSVK.S "sp|O60361|NDK8_HUMAN,sp|P22392|NDKB_HUMAN,tr|Q32Q12|Q32Q12_HUMAN" 3 1068.5564 0.97 76694 5774 2 1068.556791 535.2855 Putative nucleoside diphosphate kinase OS=Homo sapiens OX=9606 GN=NME2P1 PE=5 SV=1 6.74 1545.4 - 4.05E+06 - - - 0.3912 - 2.163 0.509 - 608.2 1 2 0 0.0004 10 0 0 0 1.12E+09 1.16E+09 - - - 4.9538 0.9998 221125_WJC_METTL3_EV_vs_WT_F06.05780.05780.2 5.76E-05 18-Dec K.LGIHEDSTNR[166.11].R sp|P08238|HS90B_HUMAN 1 1150.5606 0.85 76698 5780 2 1150.558826 576.2876 Heat shock protein HSP 90-beta OS=Homo sapiens OX=9606 GN=HSP90AB1 PE=1 SV=4 5.32 1546 - 4.77E+06 - - - -1.5592 - 1.905 0.51 - 441.3 1 2 0 -0.0018 10 0 0 0 8.20E+07 9.67E+07 - - - 4.6062 0.9986 221125_WJC_METTL3_EV_vs_WT_F06.05781.05781.2 1.36E-06 18-Nov K.LGIHEDSTNR.R sp|P08238|HS90B_HUMAN 1 1140.5523 0.84 76699 5781 2 1140.549837 571.2835 Heat shock protein HSP 90-beta OS=Homo sapiens OX=9606 GN=HSP90AB1 PE=1 SV=4 5.32 1546.1 - 4.15E+06 - - - -2.2033 - 1.935 0.272 - 325.7 1 2 0 -0.0025 10 0 0 0 8.20E+07 9.71E+07 - - - 2.8918 0.9995 221125_WJC_METTL3_EV_vs_WT_F06.05785.05785.2 0.00236 18-Oct R.NIIHGSDSVK[136.11].S "sp|O60361|NDK8_HUMAN,sp|P22392|NDKB_HUMAN,tr|Q32Q12|Q32Q12_HUMAN" 3 1076.5706 1.17 76701 5785 2 1076.568279 539.2926 Putative nucleoside diphosphate kinase OS=Homo sapiens OX=9606 GN=NME2P1 PE=5 SV=1 6.74 1546.6 - 2.64E+07 - - - -2.1308 - 2.027 0.418 - 288.6 1 2 0 -0.0023 10 0 0 0 1.11E+09 9.54E+08 - - - 4.0998 0.9999 221125_WJC_METTL3_EV_vs_WT_F06.05788.05788.2 5.86E-07 15/18 R.HGVIVAADSR[166.11].A "sp|P28074|PSB5_HUMAN,tr|H0YJM8|H0YJM8_HUMAN" 2 1033.5544 1.24 76704 5788 2 1033.5543 517.7845 Proteasome subunit beta type-5 OS=Homo sapiens OX=9606 GN=PSMB5 PE=1 SV=3 6.74 1546.8 - 9.64E+06 - - - -0.1084 - 2.661 0.477 - 845.3 1 2 0 -0.0001 10 0 0 0 1.64E+08 1.33E+08 - - - 5.2959 0.9504 221125_WJC_METTL3_EV_vs_WT_F06.05789.05789.2 12.1 14-May R.RTTWAEER.K sp|Q9BX40|LS14B_HUMAN 1 1047.5098 1.34 76705 5789 2 1047.508464 524.7622 Protein LSM14 homolog B OS=Homo sapiens OX=9606 GN=LSM14B PE=1 SV=1 6.14 1546.8 - 8.73E+06 - - - -1.2344 - 1.268 0.046 - 76.3 6 2 0 -0.0013 8 0 0 0 4.06E+08 3.02E+08 - - - -0.2511 0.9997 221125_WJC_METTL3_EV_vs_WT_F06.05790.05790.2 0.000103 14/18 R.HGVIVAADSR.A "sp|P28074|PSB5_HUMAN,tr|H0YJM8|H0YJM8_HUMAN" 2 1023.5461 1.27 76706 5790 2 1023.544082 512.7803 Proteasome subunit beta type-5 OS=Homo sapiens OX=9606 GN=PSMB5 PE=1 SV=3 6.74 1546.8 - 7.13E+06 - - - -2.0126 - 2.271 0.427 - 677.9 1 2 0 -0.0021 10 0 0 0 1.74E+08 1.37E+08 - - - 4.4837 0.9966 221125_WJC_METTL3_EV_vs_WT_F06.05791.05791.2 0.0309 12-Nov R.KMIYEQK.L "sp|Q9Y5K5|UCHL5_HUMAN,tr|H0Y4K0|H0Y4K0_HUMAN,tr|H0Y4E0|H0Y4E0_HUMAN,tr|Q5LJA9|Q5LJA9_HUMAN,tr|H0Y636|H0Y636_HUMAN,tr|H0Y6Y4|H0Y6Y4_HUMAN,tr|Q5LJB0|Q5LJB0_HUMAN,tr|Q5LJA5|Q5LJA5_HUMAN" 8 938.4895 0.8 76707 5791 2 938.485922 470.252 Ubiquitin carboxyl-terminal hydrolase isozyme L5 OS=Homo sapiens OX=9606 GN=UCHL5 PE=1 SV=3 8.5 1546.9 - 4.16E+06 - - - -3.8541 - 1.887 0.296 - 462.6 1 2 0 -0.0036 7 0 0 0 6.18E+07 7.75E+07 - - - 3.2381 0.9998 221125_WJC_METTL3_EV_vs_WT_F06.05795.05795.3 0.00012 Oct-36 K.LGIHEDSTNR.R sp|P08238|HS90B_HUMAN 1 1140.5523 0.8 76709 5795 3 1140.549886 381.1914 Heat shock protein HSP 90-beta OS=Homo sapiens OX=9606 GN=HSP90AB1 PE=1 SV=4 5.32 1547.5 - 2.55E+07 - - - -2.1604 - 1.849 0.462 - 134.1 1 2 0 -0.0025 10 0 0 0 2.65E+08 3.32E+08 - - - 5.4852 0.9464 221125_WJC_METTL3_EV_vs_WT_F06.05797.05797.2 0.188 12-Aug R.TIEK[136.11]FEK[136.11].E "sp|Q05639|EF1A2_HUMAN,sp|P68104|EF1A1_HUMAN,sp|Q5VTE0|EF1A3_HUMAN,tr|A0A2R8Y488|A0A2R8Y488_HUMAN,tr|A0A2R8YDN5|A0A2R8YDN5_HUMAN,tr|A0A7I2V659|A0A7I2V659_HUMAN,tr|A0A7I2V3H3|A0A7I2V3H3_HUMAN,tr|Q5JR01|Q5JR01_HUMAN,tr|A0A2U3TZH3|A0A2U3TZH3_HUMAN,tr|A0A7I2V5N4|A0A7I2V5N4_HUMAN,tr|A0A087WVQ9|A0A087WVQ9_HUMAN,tr|A6PW80|A6PW80_HUMAN,tr|A0A087WV01|A0A087WV01_HUMAN,tr|A0A2R8Y660|A0A2R8Y660_HUMAN,tr|A0A6Q8PFK6|A0A6Q8PFK6_HUMAN" 15 909.5142 0.39 76711 5797 2 909.51176 455.7644 Elongation factor 1-alpha 2 OS=Homo sapiens OX=9606 GN=EEF1A2 PE=1 SV=1 5.81 1547.6 - 1.33E+07 - - - -2.7201 - 1.497 0.24 - 205.1 1 2 1 -0.0025 7 0 0 0 2.11E+08 5.36E+08 - - - 2.0913 0.9989 221125_WJC_METTL3_EV_vs_WT_F06.05799.05799.2 0.0201 16-Sep R.ENPGQSLNR.L sp|P39880|CUX1_HUMAN 1 1013.489 1.76 76713 5799 2 1013.489223 507.7518 Homeobox protein cut-like 1 OS=Homo sapiens OX=9606 GN=CUX1 PE=1 SV=3 6.1 1547.8 - 2.55E+06 - - - 0.1993 - 1.575 0.269 - 364.5 1 2 0 0.0002 9 0 0 0 1.67E+08 9.47E+07 - - - 2.342 0.9996 221125_WJC_METTL3_EV_vs_WT_F06.05809.05809.2 0.0324 14-Aug K.QSQDEPLR.S "sp|Q13148|TADBP_HUMAN,tr|A0A087WX67|A0A087WX67_HUMAN,tr|G3V162|G3V162_HUMAN,tr|A0A087WV68|A0A087WV68_HUMAN,tr|A0A087WXV3|A0A087WXV3_HUMAN,tr|A0A087WYY0|A0A087WYY0_HUMAN,tr|K7EN94|K7EN94_HUMAN,tr|A0A0A0N0M3|A0A0A0N0M3_HUMAN,tr|A0A087WW61|A0A087WW61_HUMAN,tr|B1AKP7|B1AKP7_HUMAN,tr|K7EJM5|K7EJM5_HUMAN,tr|A0A087WZC9|A0A087WZC9_HUMAN,tr|A0A087WXQ5|A0A087WXQ5_HUMAN,tr|A0A087X260|A0A087X260_HUMAN" 14 971.4672 1.33 76719 5809 2 971.468238 486.7409 TAR DNA-binding protein 43 OS=Homo sapiens OX=9606 GN=TARDBP PE=1 SV=1 4.37 1548.9 - 3.12E+06 - - - 1.0448 - 1.712 0.382 - 405.2 1 2 0 0.001 8 0 0 0 7.11E+08 5.33E+08 - - - 3.4837 0.9998 221125_WJC_METTL3_EV_vs_WT_F06.05811.05811.2 3.76E-05 15/26 R.QAGPAPAAATAASK[136.11].K sp|Q9BTC0|DIDO1_HUMAN 1 1218.6448 0.88 76721 5811 2 1218.646145 610.3297 Death-inducer obliterator 1 OS=Homo sapiens OX=9606 GN=DIDO1 PE=1 SV=5 8.75 1549.1 - 2.65E+06 - - - 1.1037 - 2.569 0.489 - 606 1 2 0 0.0013 14 0 0 0 3.13E+07 3.57E+07 - - - 5.02 0.9997 221125_WJC_METTL3_EV_vs_WT_F06.05813.05813.2 0.000515 16-Oct K.QC[160.03]PTENMAR.E sp|O43395|PRPF3_HUMAN 1 1105.4645 0.56 76723 5813 2 1105.463046 553.7395 U4\U6 small nuclear ribonucleoprotein Prp3 OS=Homo sapiens OX=9606 GN=PRPF3 PE=1 SV=2 5.99 1549.3 - 2.29E+06 - - - -1.2818 - 2.077 0.374 - 411 1 2 0 -0.0014 9 0 0 0 7.25E+07 1.30E+08 - - - 3.9175 0.9577 221125_WJC_METTL3_EV_vs_WT_F06.05817.05817.2 0.000566 14-Sep L.EVQHPAAK[136.11].M "sp|P50990|TCPQ_HUMAN,tr|H7C4C8|H7C4C8_HUMAN" 2 886.4752 0.29 76725 5817 2 886.473522 444.2449 T-complex protein 1 subunit theta OS=Homo sapiens OX=9606 GN=CCT8 PE=1 SV=4 6.85 1549.8 - 1.62E+07 - - - -1.9109 - 1.551 0.406 - 364.5 1 1 0 -0.0017 8 0 0 0 7.25E+07 2.53E+08 - - - 3.3629 0.9995 221125_WJC_METTL3_EV_vs_WT_F06.05818.05818.2 0.0148 18-Nov R.ELEVQHPAAK.M "sp|P50990|TCPQ_HUMAN,tr|H7C4C8|H7C4C8_HUMAN" 2 1120.5877 0.73 76726 5818 2 1120.58674 561.3011 T-complex protein 1 subunit theta OS=Homo sapiens OX=9606 GN=CCT8 PE=1 SV=4 5.4 1549.9 - 1.83E+07 - - - -0.8326 - 1.866 0.325 - 444.2 1 2 0 -0.0009 10 0 0 0 5.22E+08 7.16E+08 - - - 3.1824 0.9998 221125_WJC_METTL3_EV_vs_WT_F06.05820.05820.2 3.92E-05 20-Nov K.ANPFGGASHAK.G "sp|P62266|RS23_HUMAN,tr|D6RDJ2|D6RDJ2_HUMAN,tr|D6R9I7|D6R9I7_HUMAN,tr|D6RD47|D6RD47_HUMAN,tr|D6RIX0|D6RIX0_HUMAN" 5 1055.5148 1.33 76728 5820 2 1055.514521 528.7647 40S ribosomal protein S23 OS=Homo sapiens OX=9606 GN=RPS23 PE=1 SV=3 8.8 1550 - 8.06E+06 - - - -0.3041 - 1.955 0.432 - 445.4 1 2 0 -0.0003 11 0 0 0 2.35E+08 1.77E+08 - - - 4.0452 0.9998 221125_WJC_METTL3_EV_vs_WT_F06.05822.05822.2 0.00146 13/18 K.EIR[166.11]PTYAGSK[136.11].S "sp|O75956|CDKA2_HUMAN,sp|O14519|CDKA1_HUMAN,tr|E9PKR4|E9PKR4_HUMAN,tr|F5GZF0|F5GZF0_HUMAN" 4 1138.6101 9.72 76730 5822 2 1138.609664 570.3123 Cyclin-dependent kinase 2-associated protein 2 OS=Homo sapiens OX=9606 GN=CDK2AP2 PE=1 SV=1 8.69 1550.2 - 2.77E+06 - - - -0.4207 - 2.613 0.304 - 600.2 1 2 0 -0.0005 10 0 0 0 4.82E+08 4.96E+07 - - - 3.9672 0.9999 221125_WJC_METTL3_EV_vs_WT_F06.05823.05823.2 1.24E-06 13/26 R.QAGPAPAAATAASK.K sp|Q9BTC0|DIDO1_HUMAN 1 1210.6306 0.88 76731 5823 2 1210.63114 606.3226 Death-inducer obliterator 1 OS=Homo sapiens OX=9606 GN=DIDO1 PE=1 SV=5 8.75 1550.3 - 2.41E+06 - - - 0.446 - 2.393 0.529 - 436.3 1 2 0 0.0005 14 0 0 0 3.13E+07 3.57E+07 - - - 5.1376 0.9998 221125_WJC_METTL3_EV_vs_WT_F06.05830.05830.2 0.011 14-Sep K.QSQDEPLR[166.11].S "sp|Q13148|TADBP_HUMAN,tr|A0A087WX67|A0A087WX67_HUMAN,tr|G3V162|G3V162_HUMAN,tr|A0A087WV68|A0A087WV68_HUMAN,tr|A0A087WXV3|A0A087WXV3_HUMAN,tr|A0A087WYY0|A0A087WYY0_HUMAN,tr|K7EN94|K7EN94_HUMAN,tr|A0A0A0N0M3|A0A0A0N0M3_HUMAN,tr|A0A087WW61|A0A087WW61_HUMAN,tr|B1AKP7|B1AKP7_HUMAN,tr|K7EJM5|K7EJM5_HUMAN,tr|A0A087WZC9|A0A087WZC9_HUMAN,tr|A0A087WXQ5|A0A087WXQ5_HUMAN,tr|A0A087X260|A0A087X260_HUMAN" 14 981.4755 1.23 76736 5830 2 981.474591 491.745 TAR DNA-binding protein 43 OS=Homo sapiens OX=9606 GN=TARDBP PE=1 SV=1 4.37 1551 - 2.83E+07 - - - -0.919 - 1.844 0.458 - 462.3 1 2 0 -0.0009 8 0 0 0 7.18E+08 5.82E+08 - - - 4.2691 0.9998 221125_WJC_METTL3_EV_vs_WT_F06.05831.05831.2 4.83E-05 16-Dec R.NAAEELK[136.11]PR[166.11].N sp|P78406|RAE1L_HUMAN 1 1044.5683 1.81 76737 5831 2 1044.566771 523.2914 mRNA export factor OS=Homo sapiens OX=9606 GN=RAE1 PE=1 SV=1 6.14 1551 - 1.89E+07 - - - -1.4427 - 2.155 0.528 - 853.7 1 2 0 -0.0015 9 0 0 0 5.80E+08 3.21E+08 - - - 5.1616 0.9997 221125_WJC_METTL3_EV_vs_WT_F06.05833.05833.2 0.00557 20-Oct K.IQSTVTQPGGK.F "sp|Q15155|NOMO1_HUMAN,sp|Q5JPE7|NOMO2_HUMAN,sp|P69849|NOMO3_HUMAN,tr|A0A7I2V686|A0A7I2V686_HUMAN,tr|A0A7I2V6B0|A0A7I2V6B0_HUMAN,tr|A0A7I2V4D7|A0A7I2V4D7_HUMAN,tr|A0A7I2V4T6|A0A7I2V4T6_HUMAN,tr|A0A087X117|A0A087X117_HUMAN,tr|A0A7I2V2V8|A0A7I2V2V8_HUMAN,tr|A0A0G2JN29|A0A0G2JN29_HUMAN,tr|A0A7I2V2Z5|A0A7I2V2Z5_HUMAN,tr|J3KN36|J3KN36_HUMAN" 12 1114.5982 1.71 76739 5833 2 1114.59872 558.3064 Nodal modulator 1 OS=Homo sapiens OX=9606 GN=NOMO1 PE=1 SV=5 8.75 1551.1 - 1.14E+07 - - - 0.4324 - 1.96 0.37 - 228.5 1 2 0 0.0005 11 0 0 0 1.55E+08 9.06E+07 - - - 3.5941 0.9879 221125_WJC_METTL3_EV_vs_WT_F06.05834.05834.2 0.000601 16-Nov E.LEVQHPAAK[136.11].M "sp|P50990|TCPQ_HUMAN,tr|H7C4C8|H7C4C8_HUMAN" 2 999.5593 0.4 76740 5834 2 999.557996 500.7869 T-complex protein 1 subunit theta OS=Homo sapiens OX=9606 GN=CCT8 PE=1 SV=4 6.75 1551.2 - 5.42E+06 - - - -1.2846 - 2.105 0.45 - 326.3 1 1 0 -0.0013 9 0 0 0 3.42E+07 8.49E+07 - - - 4.5176 0.7679 221125_WJC_METTL3_EV_vs_WT_F06.05836.05836.2 0.485 18-Apr K.YDPDPAPHME.N sp|Q96IY1|NSL1_HUMAN 1 1170.4652 - 76742 5836 2 1170.46577 586.2399 Kinetochore-associated protein NSL1 homolog OS=Homo sapiens OX=9606 GN=NSL1 PE=1 SV=3 4.31 1551.3 - 3.44E+06 - - - 0.5092 - 0.883 0.371 - 18.7 4 1 0 0.0006 10 0 0 0 - - - - - 1.1648 0.999 221125_WJC_METTL3_EV_vs_WT_F06.05839.05839.2 4.20E-07 22-Nov R.LSSDDGDSSTMR[166.11].N "sp|Q6KC79|NIPBL_HUMAN,tr|A0A590UJS4|A0A590UJS4_HUMAN" 2 1279.5226 1.49 76745 5839 2 1279.517057 640.7686 Nipped-B-like protein OS=Homo sapiens OX=9606 GN=NIPBL PE=1 SV=2 3.93 1551.7 - 1.59E+06 - - - -4.3165 - 2.265 0.613 - 427.1 1 2 0 -0.0055 12 0 0 0 2.39E+07 1.60E+07 - - - 5.7181 0.9998 221125_WJC_METTL3_EV_vs_WT_F06.05843.05843.2 0.00192 16-Oct K.NAQAQQEFK[136.11].N "sp|Q99615|DNJC7_HUMAN,tr|K7ESP1|K7ESP1_HUMAN,tr|A0A6I8PRZ0|A0A6I8PRZ0_HUMAN,tr|A0A6I8PLE7|A0A6I8PLE7_HUMAN,tr|A0A6I8PR89|A0A6I8PR89_HUMAN,tr|K7EN19|K7EN19_HUMAN,tr|A0A6I8PUC2|A0A6I8PUC2_HUMAN,tr|A0A6I8PS32|A0A6I8PS32_HUMAN,tr|K7EJL5|K7EJL5_HUMAN,tr|K7EPP7|K7EPP7_HUMAN,tr|A0A6I8PUD4|A0A6I8PUD4_HUMAN,tr|K7EIH8|K7EIH8_HUMAN,tr|K7ER44|K7ER44_HUMAN,tr|A0A6I8PU73|A0A6I8PU73_HUMAN,tr|K7EK03|K7EK03_HUMAN,tr|K7EJV7|K7EJV7_HUMAN,tr|A0A6I8PU89|A0A6I8PU89_HUMAN" 17 1070.5236 0.53 76748 5843 2 1070.523463 536.2691 DnaJ homolog subfamily C member 7 OS=Homo sapiens OX=9606 GN=DNAJC7 PE=1 SV=2 6 1552 - 1.72E+07 - - - -0.1495 - 1.924 0.438 - 480.1 1 2 0 -0.0002 9 0 0 0 9.94E+07 1.88E+08 - - - 4.1693 0.9982 221125_WJC_METTL3_EV_vs_WT_F06.05844.05844.2 0.0789 20-Oct K.ANPFGGASHAK[136.11].G "sp|P62266|RS23_HUMAN,tr|D6RDJ2|D6RDJ2_HUMAN,tr|D6R9I7|D6R9I7_HUMAN,tr|D6RD47|D6RD47_HUMAN,tr|D6RIX0|D6RIX0_HUMAN" 5 1063.529 1.24 76749 5844 2 1063.527954 532.7718 40S ribosomal protein S23 OS=Homo sapiens OX=9606 GN=RPS23 PE=1 SV=3 8.8 1552 - 1.27E+07 - - - -1.023 - 1.51 0.257 - 371.7 1 2 0 -0.0011 11 0 0 0 2.12E+08 1.72E+08 - - - 2.0537 0.9989 221125_WJC_METTL3_EV_vs_WT_F06.05856.05856.2 0.05 12-Jul K.TYFTDKK.T "sp|P27824|CALX_HUMAN,tr|A0A7P0T937|A0A7P0T937_HUMAN,tr|A0A7P0T840|A0A7P0T840_HUMAN,tr|D6RFL1|D6RFL1_HUMAN,tr|A0A7P0Z4H2|A0A7P0Z4H2_HUMAN,tr|A0A7P0TB65|A0A7P0TB65_HUMAN,tr|A0A7P0TAE9|A0A7P0TAE9_HUMAN,tr|D6RGY2|D6RGY2_HUMAN,tr|A0A7P0T8G1|A0A7P0T8G1_HUMAN,tr|A0A7P0Z4D6|A0A7P0Z4D6_HUMAN,tr|A0A7P0Z484|A0A7P0Z484_HUMAN,tr|A0A7P0TAR9|A0A7P0TAR9_HUMAN,tr|A0A7P0T9L0|A0A7P0T9L0_HUMAN" 13 901.4545 2.27 76757 5856 2 901.453536 451.7345 Calnexin OS=Homo sapiens OX=9606 GN=CANX PE=1 SV=2 8.17 1553.3 - 1.82E+07 - - - -1.106 - 1.402 0.322 - 168.7 1 2 0 -0.001 7 0 0 0 2.54E+08 1.12E+08 - - - 2.4896 0.9999 221125_WJC_METTL3_EV_vs_WT_F06.05858.05858.2 0.000602 15/22 R.ALVADSHPESER.L "sp|Q01082|SPTB2_HUMAN,tr|A0A087WUZ3|A0A087WUZ3_HUMAN" 2 1309.6262 1.73 76759 5858 2 1309.624774 655.8204 "Spectrin beta chain, non-erythrocytic 1 OS=Homo sapiens OX=9606 GN=SPTBN1 PE=1 SV=2" 4.65 1553.5 - 1.77E+06 - - - -1.1217 - 2.752 0.504 - 915.3 1 2 0 -0.0015 12 0 0 0 1.34E+07 7.75E+06 - - - 5.4267 0.998 221125_WJC_METTL3_EV_vs_WT_F06.05866.05866.2 0.303 16-Aug K.RAFDSAVAK.A "sp|Q16891|MIC60_HUMAN,tr|B9A067|B9A067_HUMAN,tr|C9J406|C9J406_HUMAN,tr|H7C463|H7C463_HUMAN" 4 963.5138 1.32 76765 5866 2 963.512946 482.7642 MICOS complex subunit MIC60 OS=Homo sapiens OX=9606 GN=IMMT PE=1 SV=1 8.75 1554.4 - 1.70E+07 - - - -0.8656 - 1.799 0.156 - 341.1 1 2 0 -0.0008 9 0 0 0 3.28E+08 2.48E+08 - - - 1.8918 0.9798 221125_WJC_METTL3_EV_vs_WT_F06.05867.05867.2 0.00697 14-Sep R.EEADKLVR.Q "sp|Q9BUJ2|HNRL1_HUMAN,tr|A0A0A0MRA5|A0A0A0MRA5_HUMAN,tr|M0R3F1|M0R3F1_HUMAN,tr|B7Z4B8|B7Z4B8_HUMAN" 4 958.5084 1.85 76766 5867 2 958.504866 480.2615 Heterogeneous nuclear ribonucleoprotein U-like protein 1 OS=Homo sapiens OX=9606 GN=HNRNPUL1 PE=1 SV=2 4.68 1554.4 - 7.44E+06 - - - -3.6452 - 2.057 0.345 - 581.9 1 2 1 -0.0035 8 0 0 0 6.49E+07 3.51E+07 - - - 3.7633 0.9577 221125_WJC_METTL3_EV_vs_WT_F06.05868.05868.2 2.93 14-Jun K.VPEPC[160.03]QPK.V "sp|P35321|SPR1A_HUMAN,sp|P22528|SPR1B_HUMAN" 2 953.4641 0.41 76767 5868 2 953.462788 477.7393 Cornifin-A OS=Homo sapiens OX=9606 GN=SPRR1A PE=1 SV=2 5.97 1554.5 - 3.06E+06 - - - -1.3257 - 1.087 0.08 - 151.1 1 2 0 -0.0013 8 0 0 0 2.54E+07 6.16E+07 - - - -0.1169 0.9988 221125_WJC_METTL3_EV_vs_WT_F06.05870.05870.2 6.93E-05 13/22 R.ALVADSHPESER[166.11].L "sp|Q01082|SPTB2_HUMAN,tr|A0A087WUZ3|A0A087WUZ3_HUMAN" 2 1319.6345 1.73 76769 5870 2 1319.63042 660.8245 "Spectrin beta chain, non-erythrocytic 1 OS=Homo sapiens OX=9606 GN=SPTBN1 PE=1 SV=2" 4.65 1554.8 - 1.36E+06 - - - -3.1016 - 2.365 0.344 - 645.8 1 2 0 -0.0041 12 0 0 0 1.34E+07 7.75E+06 - - - 3.8454 0.9998 221125_WJC_METTL3_EV_vs_WT_F06.05878.05878.2 3.12E-05 16-Oct R.QQYESVAAK.N "sp|P08670|VIME_HUMAN,tr|B0YJC5|B0YJC5_HUMAN,tr|B0YJC4|B0YJC4_HUMAN" 3 1022.5033 1.9 76776 5878 2 1022.503647 512.2589 Vimentin OS=Homo sapiens OX=9606 GN=VIM PE=1 SV=4 6 1555.5 - 1.68E+07 - - - 0.3638 - 1.991 0.473 - 531.9 1 2 0 0.0004 9 0 0 0 4.05E+09 2.13E+09 - - - 4.5267 0.9999 221125_WJC_METTL3_EV_vs_WT_F06.05880.05880.2 1.33E-05 16-Sep R.QQYESVAAK[136.11].N "sp|P08670|VIME_HUMAN,tr|B0YJC5|B0YJC5_HUMAN,tr|B0YJC4|B0YJC4_HUMAN" 3 1030.5175 1.9 76778 5880 2 1030.516976 516.266 Vimentin OS=Homo sapiens OX=9606 GN=VIM PE=1 SV=4 6 1555.6 - 1.07E+07 - - - -0.4842 - 1.989 0.526 - 444.8 1 2 0 -0.0005 9 0 0 0 4.05E+09 2.13E+09 - - - 4.9152 0.9998 221125_WJC_METTL3_EV_vs_WT_F06.05881.05881.2 7.90E-08 18-Oct R.EHALTSGTIK[136.11].A "sp|Q15369|ELOC_HUMAN,tr|R4GMY8|R4GMY8_HUMAN,tr|E5RHG8|E5RHG8_HUMAN" 3 1063.5753 0.94 76779 5881 2 1063.573477 532.7949 Elongin-C OS=Homo sapiens OX=9606 GN=ELOC PE=1 SV=1 6.85 1555.6 - 1.02E+07 - - - -1.7366 - 1.997 0.555 - 425.2 1 2 0 -0.0018 10 0 0 0 8.40E+07 8.94E+07 - - - 5.0702 0.9999 221125_WJC_METTL3_EV_vs_WT_F06.05882.05882.2 6.96E-07 18-Nov R.EHALTSGTIK.A "sp|Q15369|ELOC_HUMAN,tr|R4GMY8|R4GMY8_HUMAN,tr|E5RHG8|E5RHG8_HUMAN" 3 1055.5611 0.91 76780 5882 2 1055.560586 528.7878 Elongin-C OS=Homo sapiens OX=9606 GN=ELOC PE=1 SV=1 6.85 1555.6 - 9.87E+06 - - - -0.5097 - 2.014 0.524 - 537 1 2 0 -0.0005 10 0 0 0 8.11E+07 8.90E+07 - - - 4.8654 0.9917 221125_WJC_METTL3_EV_vs_WT_F06.05884.05884.2 0.277 16-Jun R.DLTQEQTEK.L sp|Q96CS3|FAF2_HUMAN 1 1090.5142 0.49 76782 5884 2 1090.516344 546.2644 FAS-associated factor 2 OS=Homo sapiens OX=9606 GN=FAF2 PE=1 SV=2 4.14 1555.7 - 4.32E+06 - - - 1.9358 - 1.411 0.173 - 93.3 1 2 0 0.0021 9 0 0 0 6.15E+07 1.26E+08 - - - 1.3142 0.9999 221125_WJC_METTL3_EV_vs_WT_F06.05885.05885.2 1.95E-06 22-Dec R.VTTGTSNTTAIK[136.11].S sp|Q15291|RBBP5_HUMAN 1 1200.6441 0.85 76783 5885 2 1200.643485 601.3293 Retinoblastoma-binding protein 5 OS=Homo sapiens OX=9606 GN=RBBP5 PE=1 SV=2 8.72 1555.8 - 3.40E+06 - - - -0.5389 - 2.524 0.456 - 601.5 1 2 0 -0.0006 12 0 0 0 1.58E+07 1.85E+07 - - - 4.8449 0.9999 221125_WJC_METTL3_EV_vs_WT_F06.05886.05886.2 8.39E-06 22-Nov R.VTTGTSNTTAIK.S sp|Q15291|RBBP5_HUMAN 1 1192.6299 0.85 76784 5886 2 1192.629996 597.3222 Retinoblastoma-binding protein 5 OS=Homo sapiens OX=9606 GN=RBBP5 PE=1 SV=2 8.72 1555.9 - 2.74E+06 - - - 0.0537 - 2.271 0.517 - 415.4 1 2 0 0.0001 12 0 0 0 1.58E+07 1.85E+07 - - - 5.0177 0.9996 221125_WJC_METTL3_EV_vs_WT_F06.05889.05889.2 1.53E-06 20-Nov R.FC[160.03]ENTQAGEGR[166.11].V "sp|Q92896|GSLG1_HUMAN,tr|H3BM42|H3BM42_HUMAN" 2 1277.5334 1.25 76787 5889 2 1277.529481 639.774 Golgi apparatus protein 1 OS=Homo sapiens OX=9606 GN=GLG1 PE=1 SV=2 4.53 1556.3 - 2.29E+06 - - - -3.0825 - 2.192 0.575 - 385.8 1 2 0 -0.0039 11 0 0 0 1.19E+07 9.52E+06 - - - 5.4098 0.934 221125_WJC_METTL3_EV_vs_WT_F06.05891.05891.2 0.00208 18-Jul L.VADSHPESER[166.11].L "sp|Q01082|SPTB2_HUMAN,tr|A0A087WUZ3|A0A087WUZ3_HUMAN" 2 1135.5133 1.39 76789 5891 2 1135.514792 568.7639 "Spectrin beta chain, non-erythrocytic 1 OS=Homo sapiens OX=9606 GN=SPTBN1 PE=1 SV=2" 4.65 1556.5 - 924275 - - - 1.2831 - 1.466 0.338 - 139.9 1 1 0 0.0015 10 0 0 0 8.00E+06 5.77E+06 - - - 2.6048 1 221125_WJC_METTL3_EV_vs_WT_F06.05894.05894.3 2.76E-05 13/44 R.ALVADSHPESER.L "sp|Q01082|SPTB2_HUMAN,tr|A0A087WUZ3|A0A087WUZ3_HUMAN" 2 1309.6262 1.84 76791 5894 3 1309.624537 437.5494 "Spectrin beta chain, non-erythrocytic 1 OS=Homo sapiens OX=9606 GN=SPTBN1 PE=1 SV=2" 4.65 1556.8 - 5.33E+06 - - - -1.3027 - 2.312 0.544 - 253.9 1 2 0 -0.0017 12 0 0 0 1.23E+08 6.69E+07 - - - 6.9277 0.9995 221125_WJC_METTL3_EV_vs_WT_F06.05896.05896.2 0.0158 14-Sep K.WTTEQQQR[166.11].F "sp|Q15041|AR6P1_HUMAN,tr|H3BPJ2|H3BPJ2_HUMAN,tr|H3BN98|H3BN98_HUMAN" 3 1085.5129 0.89 76792 5896 2 1085.511447 543.7637 ADP-ribosylation factor-like protein 6-interacting protein 1 OS=Homo sapiens OX=9606 GN=ARL6IP1 PE=1 SV=2 6 1557 - 7.59E+06 - - - -1.3763 - 1.905 0.339 - 364.2 1 2 0 -0.0015 8 0 0 0 5.35E+07 6.00E+07 - - - 3.4881 0.9987 221125_WJC_METTL3_EV_vs_WT_F06.05897.05897.2 0.457 14-Sep K.WTTEQQQR.F "sp|Q15041|AR6P1_HUMAN,tr|H3BPJ2|H3BPJ2_HUMAN,tr|H3BN98|H3BN98_HUMAN" 3 1075.5047 0.87 76793 5897 2 1075.502256 538.7596 ADP-ribosylation factor-like protein 6-interacting protein 1 OS=Homo sapiens OX=9606 GN=ARL6IP1 PE=1 SV=2 6 1557.1 - 7.79E+06 - - - -2.2455 - 1.627 0.343 - 368.9 1 2 0 -0.0024 8 0 0 0 5.35E+07 6.14E+07 - - - 3.0416 0.9995 221125_WJC_METTL3_EV_vs_WT_F06.05898.05898.2 0.00043 18-Oct K.TQGQQVSSLK.D "sp|Q96F86|EDC3_HUMAN,tr|H3BPN4|H3BPN4_HUMAN" 2 1074.5669 1.21 76794 5898 2 1074.56586 538.2907 Enhancer of mRNA-decapping protein 3 OS=Homo sapiens OX=9606 GN=EDC3 PE=1 SV=1 8.41 1557.1 - 7.79E+06 - - - -1.0023 - 1.811 0.336 - 329.7 1 2 0 -0.0011 10 0 0 0 4.00E+07 3.30E+07 - - - 3.1801 0.9998 221125_WJC_METTL3_EV_vs_WT_F06.05899.05899.2 0.000218 14-Oct R.THINYGVK[136.11].G "sp|P40939|ECHA_HUMAN,tr|A0A2R8YG21|A0A2R8YG21_HUMAN,tr|A0A2R8Y688|A0A2R8Y688_HUMAN,tr|H0YFD6|H0YFD6_HUMAN,tr|A0A2R8Y4F5|A0A2R8Y4F5_HUMAN" 5 938.5065 1.78 76795 5899 2 938.505529 470.2605 "Trifunctional enzyme subunit alpha, mitochondrial OS=Homo sapiens OX=9606 GN=HADHA PE=1 SV=2" 8.29 1557.2 - 4.79E+06 - - - -1.0517 - 1.899 0.447 - 488.8 1 2 0 -0.001 8 0 0 0 1.45E+08 8.16E+07 - - - 4.2764 0.9996 221125_WJC_METTL3_EV_vs_WT_F06.05901.05901.2 0.000229 16-Aug K.TC[160.03]ATDLQTK.A "sp|O95861|BPNT1_HUMAN,tr|F8W1J0|F8W1J0_HUMAN,tr|F8VVW8|F8VVW8_HUMAN,tr|A6NF51|A6NF51_HUMAN,tr|F8VZG4|F8VZG4_HUMAN" 5 1036.4859 0.18 76797 5901 2 1036.48633 519.2502 "3'(2'),5'-bisphosphate nucleotidase 1 OS=Homo sapiens OX=9606 GN=BPNT1 PE=1 SV=1" 5.5 1557.3 - 2.88E+06 - - - 0.4052 - 1.596 0.415 - 246.9 1 2 0 0.0004 9 0 0 0 1.73E+07 9.43E+07 - - - 3.4586 0.7898 221125_WJC_METTL3_EV_vs_WT_F06.05906.05906.2 1.57 22-Jul K.VSTSGSSVDSSK[136.11].K sp|Q15648|MED1_HUMAN 1 1147.5448 0.1 76802 5906 2 1147.550562 574.7797 Mediator of RNA polymerase II transcription subunit 1 OS=Homo sapiens OX=9606 GN=MED1 PE=1 SV=4 5.81 1557.7 - 899410 - - - 5.0107 - 1.197 0.125 - 129.4 1 2 0 0.0057 12 0 0 0 9.92E+05 9.74E+06 - - - 0.4356 0.9995 221125_WJC_METTL3_EV_vs_WT_F06.05913.05913.2 5.17E-06 18-Oct R.DAVTYTEHAK.R sp|P62805|H4_HUMAN 1 1133.5353 1.12 76807 5913 2 1133.534363 567.7749 Histone H4 OS=Homo sapiens OX=9606 GN=H4C1 PE=1 SV=2 5.32 1558.3 - 2.39E+06 - - - -0.8293 - 2.247 0.251 - 440 1 2 0 -0.0009 10 0 0 0 5.34E+08 4.78E+08 - - - 3.1544 0.9899 221125_WJC_METTL3_EV_vs_WT_F06.05918.05918.3 0.359 Sep-36 R.LLQEEEQERR.R "sp|O14654|IRS4_HUMAN,tr|A0A804CF45|A0A804CF45_HUMAN" 2 1328.6684 1.18 76812 5918 3 1328.66794 443.8968 Insulin receptor substrate 4 OS=Homo sapiens OX=9606 GN=IRS4 PE=1 SV=1 4.49 1558.9 - 1.07E+06 - - - -0.3778 - 1.524 0.182 - 144.9 1 2 0 -0.0005 10 0 0 0 2.99E+07 2.52E+07 - - - 1.7995 0.9911 221125_WJC_METTL3_EV_vs_WT_F06.05923.05923.3 0.22 Oct-36 K.LEVQAEEERK.Q sp|Q9H307|PININ_HUMAN 1 1229.6252 1.44 76815 5923 3 1229.62294 410.8823 Pinin OS=Homo sapiens OX=9606 GN=PNN PE=1 SV=5 4.49 1559.5 - 6.63E+06 - - - -1.8225 - 1.518 0.216 - 89.1 1 2 0 -0.0022 10 0 0 0 7.50E+07 5.22E+07 - - - 2.1665 0.9944 221125_WJC_METTL3_EV_vs_WT_F06.05925.05925.2 3.62E-06 22-Dec K.IDSEGGVSANHT.S "sp|P51659|DHB4_HUMAN,tr|A0A2R8Y7L2|A0A2R8Y7L2_HUMAN,tr|A0A2R8YD50|A0A2R8YD50_HUMAN,tr|A0A804HIR1|A0A804HIR1_HUMAN,tr|E7ET17|E7ET17_HUMAN,tr|E7ER27|E7ER27_HUMAN,tr|E7EPL9|E7EPL9_HUMAN,tr|A0A804HKU2|A0A804HKU2_HUMAN,tr|A0A804HK65|A0A804HK65_HUMAN" 9 1185.5262 - 76817 5925 2 1185.525324 593.7704 Peroxisomal multifunctional enzyme type 2 OS=Homo sapiens OX=9606 GN=HSD17B4 PE=1 SV=3 4.35 1559.6 - 4.68E+06 - - - -0.7347 - 2.235 0.596 - 404.1 1 1 0 -0.0009 12 0 0 0 - - - - - 5.5589 0.9998 221125_WJC_METTL3_EV_vs_WT_F06.05926.05926.2 0.0103 16-Oct K.TEGSDLC[160.03]DR[166.11].V "sp|P04843|RPN1_HUMAN,tr|B7Z4L4|B7Z4L4_HUMAN" 2 1061.4323 1.39 76818 5926 2 1061.431751 531.7234 Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit 1 OS=Homo sapiens OX=9606 GN=RPN1 PE=1 SV=1 4.03 1559.6 - 2.71E+06 - - - -0.5248 - 1.731 0.522 - 349.7 1 2 0 -0.0006 9 0 0 0 3.11E+07 2.23E+07 - - - 4.4837 0.8686 221125_WJC_METTL3_EV_vs_WT_F06.05929.05929.2 0.0452 22-Nov K.QNAETASAVATR[166.11].T "sp|Q8NI08|NCOA7_HUMAN,tr|Q5TF98|Q5TF98_HUMAN,tr|Q5TF96|Q5TF96_HUMAN,tr|Q5TF97|Q5TF97_HUMAN" 4 1227.6083 0.5 76821 5929 2 1228.614479 614.8114 Nuclear receptor coactivator 7 OS=Homo sapiens OX=9606 GN=NCOA7 PE=1 SV=2 6 1560 - 1.08E+06 - - - 819.6263 - 1.718 0.27 - 269.3 1 2 0 1.0062 12 0 0 0 1.13E+07 2.24E+07 - - - 2.1432 0.978 221125_WJC_METTL3_EV_vs_WT_F06.05935.05935.2 0.0472 16-Sep K.LRC[160.03]DSADLR.H "sp|Q9NYF8|BCLF1_HUMAN,tr|E9PKI6|E9PKI6_HUMAN,tr|E9PK91|E9PK91_HUMAN,tr|E9PK09|E9PK09_HUMAN,tr|E9PQN2|E9PQN2_HUMAN" 5 1104.5346 1.93 76825 5935 2 1104.53418 553.2746 Bcl-2-associated transcription factor 1 OS=Homo sapiens OX=9606 GN=BCLAF1 PE=1 SV=2 5.95 1560.6 - 9.90E+06 - - - -0.373 - 1.539 0.204 - 257.9 1 2 1 -0.0004 9 0 0 0 2.37E+08 1.23E+08 - - - 1.7949 0.9982 221125_WJC_METTL3_EV_vs_WT_F06.05936.05936.2 1.39 12-Aug K.EHEVFQR.D sp|O60884|DNJA2_HUMAN 1 943.4512 0.39 76826 5936 2 943.450038 472.7329 DnaJ homolog subfamily A member 2 OS=Homo sapiens OX=9606 GN=DNAJA2 PE=1 SV=1 5.4 1560.6 - 7.27E+06 - - - -1.2094 - 1.622 0.205 - 433 1 2 0 -0.0011 7 0 0 0 7.37E+07 1.89E+08 - - - 2.0873 0.9943 221125_WJC_METTL3_EV_vs_WT_F06.05937.05937.2 0.00978 16-Oct K.LR[166.11]C[160.03]DSADLR[166.11].H "sp|Q9NYF8|BCLF1_HUMAN,tr|E9PKI6|E9PKI6_HUMAN,tr|E9PK91|E9PK91_HUMAN,tr|E9PK09|E9PK09_HUMAN,tr|E9PQN2|E9PQN2_HUMAN" 5 1124.5511 1.93 76827 5937 2 1124.550319 563.2828 Bcl-2-associated transcription factor 1 OS=Homo sapiens OX=9606 GN=BCLAF1 PE=1 SV=2 5.95 1560.6 - 6.10E+06 - - - -0.723 - 1.826 0.31 - 316.6 1 2 1 -0.0008 9 0 0 0 2.37E+08 1.23E+08 - - - 3.0724 0.9997 221125_WJC_METTL3_EV_vs_WT_F06.05938.05938.2 0.0179 16-Jul K.TEGSDLC[160.03]DR.V "sp|P04843|RPN1_HUMAN,tr|B7Z4L4|B7Z4L4_HUMAN" 2 1051.424 1.39 76828 5938 2 1051.422991 526.7193 Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit 1 OS=Homo sapiens OX=9606 GN=RPN1 PE=1 SV=1 4.03 1560.7 - 4.11E+06 - - - -0.9958 - 1.315 0.522 - 148.9 1 2 0 -0.001 9 0 0 0 3.11E+07 2.23E+07 - - - 3.6884 0.8326 221125_WJC_METTL3_EV_vs_WT_F06.05945.05945.2 5.05 14-Jul P.DGIISK[136.11]PK[136.11].N sp|Q86U44|MTA70_HUMAN 1 872.5302 0.01 76833 5945 2 872.529267 437.2724 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 8.59 1561.5 - 9.47E+06 - - - -1.0899 - 1.324 0.227 - 158.7 1 1 0 -0.001 8 0 0 0 3.81E+06 6.65E+08 - - - 1.5638 0.9993 221125_WJC_METTL3_EV_vs_WT_F06.05946.05946.2 0.00815 14-Sep R.FHVEEEGK.G "sp|P07205|PGK2_HUMAN,sp|P00558|PGK1_HUMAN" 2 973.4505 1.26 76834 5946 2 973.450075 487.7325 Phosphoglycerate kinase 2 OS=Homo sapiens OX=9606 GN=PGK2 PE=1 SV=3 4.75 1561.6 - 1.69E+06 - - - -0.4479 - 1.577 0.32 - 455.8 1 2 0 -0.0004 8 0 0 0 2.14E+07 1.70E+07 - - - 2.7782 0.9998 221125_WJC_METTL3_EV_vs_WT_F06.05947.05947.2 0.00027 16-Aug R.EAC[160.03]TC[160.03]PYC[160.03]K[136.11].D sp|P08047|SP1_HUMAN 1 1195.4552 0.98 76835 5947 2 1195.456625 598.7349 Transcription factor Sp1 OS=Homo sapiens OX=9606 GN=SP1 PE=1 SV=3 6.07 1561.7 - 3.83E+06 - - - 1.233 - 1.52 0.658 - 252.9 1 2 0 0.0015 9 0 0 0 5.16E+07 5.25E+07 - - - 5.1119 0.9936 221125_WJC_METTL3_EV_vs_WT_F06.05948.05948.2 0.447 14-Jul R.K[136.11]IPVPANR[166.11].Y "sp|Q9NRX1|PNO1_HUMAN,tr|F8WBJ6|F8WBJ6_HUMAN" 2 911.5672 0.75 76836 5948 2 911.565992 456.7909 RNA-binding protein PNO1 OS=Homo sapiens OX=9606 GN=PNO1 PE=1 SV=1 11 1561.8 - 2.94E+06 - - - -1.2769 - 1.491 0.123 - 158.5 1 2 0 -0.0012 8 0 0 0 4.60E+07 6.17E+07 - - - 1.1538 1 221125_WJC_METTL3_EV_vs_WT_F06.05951.05951.2 5.17E-07 13/24 K.IDGATQSSPAEPK[136.11].S sp|Q32MZ4|LRRF1_HUMAN 1 1307.6449 0.58 76839 5951 2 1307.643728 654.8297 Leucine-rich repeat flightless-interacting protein 1 OS=Homo sapiens OX=9606 GN=LRRFIP1 PE=1 SV=2 4.37 1562.1 - 575712 - - - -0.8657 - 2.567 0.579 - 509.8 1 2 0 -0.0011 13 0 0 0 1.43E+07 2.45E+07 - - - 5.7367 0.9995 221125_WJC_METTL3_EV_vs_WT_F06.05956.05956.2 0.0419 14-Nov R.KLEEIEAK.N "sp|O75179|ANR17_HUMAN,tr|H0YM23|H0YM23_HUMAN" 2 958.5335 2.56 76842 5956 2 958.532266 480.274 Ankyrin repeat domain-containing protein 17 OS=Homo sapiens OX=9606 GN=ANKRD17 PE=1 SV=3 4.79 1562.7 - 1.42E+06 - - - -1.2999 - 1.849 0.328 - 442.6 1 2 0 -0.0012 8 0 0 0 3.98E+07 1.55E+07 - - - 3.317 0.9998 221125_WJC_METTL3_EV_vs_WT_F06.05958.05958.2 0.000241 16-Sep R.EAC[160.03]TC[160.03]PYC[160.03]K.D sp|P08047|SP1_HUMAN 1 1187.441 0.98 76843 5958 2 1187.44254 594.7278 Transcription factor Sp1 OS=Homo sapiens OX=9606 GN=SP1 PE=1 SV=3 6.07 1562.8 - 3.81E+06 - - - 1.3382 - 1.537 0.632 - 372.5 1 2 0 0.0016 9 0 0 0 5.16E+07 5.25E+07 - - - 4.952 0.9995 221125_WJC_METTL3_EV_vs_WT_F06.05959.05959.2 0.0329 14-Sep K.K[136.11]LTSDLGR[166.11].A "sp|Q9P2E9|RRBP1_HUMAN,tr|A0A087WU26|A0A087WU26_HUMAN,tr|A0A087WVV2|A0A087WVV2_HUMAN,tr|F8W7S5|F8W7S5_HUMAN" 4 906.5254 1.19 76844 5959 2 906.524709 454.27 Ribosome-binding protein 1 OS=Homo sapiens OX=9606 GN=RRBP1 PE=1 SV=5 8.75 1562.9 - 2.52E+06 - - - -0.7082 - 2.012 0.27 - 348.5 1 2 0 -0.0006 8 0 0 0 4.36E+07 3.66E+07 - - - 3.1436 0.9828 221125_WJC_METTL3_EV_vs_WT_F06.05961.05961.2 0.514 12-Jun R.R[166.11]IEIQPK[136.11].H "sp|P35606|COPB2_HUMAN,tr|H0Y938|H0Y938_HUMAN,tr|A0A7I2V258|A0A7I2V258_HUMAN,tr|H0YAC7|H0YAC7_HUMAN" 4 900.5512 0.56 76846 5961 2 900.550813 451.2829 Coatomer subunit beta' OS=Homo sapiens OX=9606 GN=COPB2 PE=1 SV=2 8.75 1563.1 - 1.73E+06 - - - -0.3975 - 1.288 0.057 - 199.7 1 2 0 -0.0004 7 0 0 0 2.13E+07 3.84E+07 - - - 0.2638 0.9999 221125_WJC_METTL3_EV_vs_WT_F06.05962.05962.2 0.00132 24-Dec K.IDGATQSSPAEPK.S sp|Q32MZ4|LRRF1_HUMAN 1 1299.6307 0.52 76847 5962 2 1299.6321 650.8226 Leucine-rich repeat flightless-interacting protein 1 OS=Homo sapiens OX=9606 GN=LRRFIP1 PE=1 SV=2 4.37 1563.2 - 686421 - - - 1.108 - 2.686 0.489 - 514.7 1 2 0 0.0014 13 0 0 0 1.43E+07 2.77E+07 - - - 5.1882 0.9842 221125_WJC_METTL3_EV_vs_WT_F06.05963.05963.2 0.042 22-Aug K.EVNGQPVGSDPR.A "sp|Q14168|MPP2_HUMAN,tr|E5RI47|E5RI47_HUMAN,tr|B4DZ84|B4DZ84_HUMAN,tr|D3DX49|D3DX49_HUMAN,tr|A0A0A0MRU0|A0A0A0MRU0_HUMAN,tr|A0A0C4DH75|A0A0C4DH75_HUMAN,tr|A0A0D9SFF8|A0A0D9SFF8_HUMAN,tr|D3DX48|D3DX48_HUMAN" 8 1253.6 2.71 76848 5963 2 1253.604238 627.8073 MAGUK p55 subfamily member 2 OS=Homo sapiens OX=9606 GN=MPP2 PE=1 SV=3 4.37 1563.3 - 496596 - - - 3.3575 - 1.41 0.219 - 123.5 1 2 0 0.0042 12 0 0 0 9.66E+06 3.57E+06 - - - 1.5613 0.8767 221125_WJC_METTL3_EV_vs_WT_F06.05967.05967.2 0.00833 14-Jul M.KSDSFAPK.T "sp|Q9Y2W1|TR150_HUMAN,tr|A0A3B3ITZ9|A0A3B3ITZ9_HUMAN" 2 878.4498 5.58 76850 5967 2 878.448677 440.2322 Thyroid hormone receptor-associated protein 3 OS=Homo sapiens OX=9606 GN=THRAP3 PE=1 SV=2 8.59 1563.8 - 6.20E+06 - - - -1.2579 - 1.39 0.254 - 154 1 1 0 -0.0011 8 0 0 0 1.23E+08 2.21E+07 - - - 1.9099 0.9994 221125_WJC_METTL3_EV_vs_WT_F06.05968.05968.2 0.00168 12-Jul K.HGYIPGK[136.11].N "sp|Q9ULV4|COR1C_HUMAN,tr|H0YHL7|H0YHL7_HUMAN,tr|B4E3S0|B4E3S0_HUMAN" 3 778.4217 0.66 76851 5968 2 778.421372 390.2181 Coronin-1C OS=Homo sapiens OX=9606 GN=CORO1C PE=1 SV=1 8.6 1563.8 - 6.48E+06 - - - -0.4522 - 1.385 0.388 - 299.1 1 2 0 -0.0004 7 0 0 0 4.68E+07 7.10E+07 - - - 2.9387 0.9983 221125_WJC_METTL3_EV_vs_WT_F06.05970.05970.2 0.373 14-Aug K.KLTSDLGR.A "sp|Q9P2E9|RRBP1_HUMAN,tr|A0A087WU26|A0A087WU26_HUMAN,tr|A0A087WVV2|A0A087WVV2_HUMAN,tr|F8W7S5|F8W7S5_HUMAN" 4 888.5029 1.24 76853 5970 2 888.50174 445.2587 Ribosome-binding protein 1 OS=Homo sapiens OX=9606 GN=RRBP1 PE=1 SV=5 8.75 1563.9 - 3.62E+06 - - - -1.2842 - 1.902 0.165 - 266.8 1 2 0 -0.0011 8 0 0 0 4.51E+07 3.63E+07 - - - 2.1983 0.9994 221125_WJC_METTL3_EV_vs_WT_F06.05975.05975.2 0.00473 22-Dec K.DASAAEPAAAER[166.11].V sp|Q9UHR6|ZNHI2_HUMAN 1 1167.5395 1.39 76858 5975 2 1167.537014 584.7771 Zinc finger HIT domain-containing protein 2 OS=Homo sapiens OX=9606 GN=ZNHIT2 PE=1 SV=1 4.14 1564.4 - 925319 - - - -2.1721 - 2.053 0.4 - 227.4 1 2 0 -0.0025 12 0 0 0 1.45E+07 1.04E+07 - - - 3.8872 0.9965 221125_WJC_METTL3_EV_vs_WT_F06.05978.05978.2 0.00857 14-Sep R.LSK[136.11]EDIER[166.11].M "sp|P11142|HSP7C_HUMAN,tr|E9PNE6|E9PNE6_HUMAN,tr|A8K7Q2|A8K7Q2_HUMAN,tr|E9PKE3|E9PKE3_HUMAN,tr|E9PM13|E9PM13_HUMAN,tr|E9PS65|E9PS65_HUMAN" 6 1006.5414 0.88 76859 5978 2 1006.541282 504.278 Heat shock cognate 71 kDa protein OS=Homo sapiens OX=9606 GN=HSPA8 PE=1 SV=1 4.68 1564.8 - 6.62E+07 - - - -0.1123 - 2.019 0.317 - 322.8 1 2 1 -0.0001 8 0 0 0 5.42E+09 6.14E+09 - - - 3.5013 0.9985 221125_WJC_METTL3_EV_vs_WT_F06.05980.05980.3 0.00119 Oct-36 R.FIDEETKDTK.G "sp|Q96BD8|SKA1_HUMAN,tr|K7EPW0|K7EPW0_HUMAN,tr|K7EP61|K7EP61_HUMAN" 3 1224.5874 1.82 76861 5980 3 1224.58581 409.2031 Spindle and kinetochore-associated protein 1 OS=Homo sapiens OX=9606 GN=SKA1 PE=1 SV=1 4.32 1564.9 - 4.02E+06 - - - -1.2968 - 1.807 0.359 - 73.3 1 2 1 -0.0016 10 0 0 0 4.19E+07 2.30E+07 - - - 4.27 0.9996 221125_WJC_METTL3_EV_vs_WT_F06.05984.05984.2 0.00241 20-Aug R.GPPPSYGGSSR[166.11].Y "sp|Q96E39|RMXL1_HUMAN,sp|P38159|RBMX_HUMAN,tr|H3BUY5|H3BUY5_HUMAN" 3 1070.502 2.42 76865 5984 2 1070.501448 536.2583 "RNA binding motif protein, X-linked-like-1 OS=Homo sapiens OX=9606 GN=RBMXL1 PE=1 SV=1" 8.75 1565.2 - 1.31E+06 - - - -0.5549 - 1.406 0.452 - 197.6 1 2 0 -0.0006 11 0 0 0 2.52E+08 1.04E+08 - - - 3.3011 0.9998 221125_WJC_METTL3_EV_vs_WT_F06.05986.05986.2 0.00919 16-Dec K.IQESHPELR[166.11].R sp|Q9H9B4|SFXN1_HUMAN 1 1117.5755 0.86 76867 5986 2 1117.574142 559.795 Sideroflexin-1 OS=Homo sapiens OX=9606 GN=SFXN1 PE=1 SV=4 5.4 1565.5 - 836613 - - - -1.2527 - 2.327 0.394 - 476.5 1 2 0 -0.0014 9 0 0 0 1.45E+07 1.70E+07 - - - 4.3941 0.9996 221125_WJC_METTL3_EV_vs_WT_F06.05988.05988.2 3.95E-07 22-Dec R.LEEAQSEAPETK.G sp|Q8N196|SIX5_HUMAN 1 1330.6252 0.31 76869 5988 2 1330.621415 666.3199 Homeobox protein SIX5 OS=Homo sapiens OX=9606 GN=SIX5 PE=1 SV=3 4.09 1565.7 - 304771 - - - -2.8746 - 2.09 0.558 - 463.4 1 2 0 -0.0038 12 0 0 0 2.74E+06 8.85E+06 - - - 5.1008 0.9996 221125_WJC_METTL3_EV_vs_WT_F06.05994.05994.3 0.111 15/44 R.GTVQALHATGAR.V "sp|Q7Z4W1|DCXR_HUMAN,tr|J3KS22|J3KS22_HUMAN,tr|J3QS36|J3QS36_HUMAN" 3 1180.6313 5.97 76873 5994 3 1180.631478 394.551 L-xylulose reductase OS=Homo sapiens OX=9606 GN=DCXR PE=1 SV=2 9.76 1566.4 - 1.52E+06 - - - 0.177 - 2.254 0.282 - 239.7 1 2 0 0.0002 12 0 0 0 4.80E+07 8.03E+06 - - - 3.9367 0.9848 221125_WJC_METTL3_EV_vs_WT_F06.05995.05995.2 7.59E-05 14-Sep K.FHNELNAH.L sp|P12270|TPR_HUMAN 1 980.4464 - 76874 5995 2 980.445388 491.2305 Nucleoprotein TPR OS=Homo sapiens OX=9606 GN=TPR PE=1 SV=3 5.98 1566.5 - 1.50E+06 - - - -1.0607 - 1.729 0.451 - 274.1 1 1 0 -0.001 8 0 0 0 - - - - - 4.0231 0.9938 221125_WJC_METTL3_EV_vs_WT_F06.06000.06000.2 1.48E-05 22-Dec T.QSVEGATGSAVK.S "sp|Q14157|UBP2L_HUMAN,tr|F8W726|F8W726_HUMAN" 2 1132.5724 3.13 76877 6000 2 1132.572338 567.2935 Ubiquitin-associated protein 2-like OS=Homo sapiens OX=9606 GN=UBAP2L PE=1 SV=2 6 1567.1 - 3.35E+06 - - - -0.0698 - 2.492 0.5 - 602.3 1 1 0 -0.0001 12 0 0 0 6.21E+07 1.98E+07 - - - 5.1365 0.9988 221125_WJC_METTL3_EV_vs_WT_F06.06001.06001.2 0.0301 14-Jul K.NAQLELK[136.11]K[136.11].S "sp|Q99615|DNJC7_HUMAN,tr|A0A6I8PRZ0|A0A6I8PRZ0_HUMAN,tr|A0A6I8PR89|A0A6I8PR89_HUMAN,tr|A0A6I8PIK4|A0A6I8PIK4_HUMAN,tr|A0A6I8PS32|A0A6I8PS32_HUMAN,tr|A0A6I8PUD4|A0A6I8PUD4_HUMAN,tr|K7ER44|K7ER44_HUMAN,tr|A0A6I8PU73|A0A6I8PU73_HUMAN" 8 958.5782 0.66 76878 6001 2 958.578059 480.2964 DnaJ homolog subfamily C member 7 OS=Homo sapiens OX=9606 GN=DNAJC7 PE=1 SV=2 8.59 1567.2 - 1.24E+06 - - - -0.1794 - 1.329 0.309 - 152.2 1 2 0 -0.0002 8 0 0 0 3.62E+07 5.48E+07 - - - 2.181 0.9998 221125_WJC_METTL3_EV_vs_WT_F06.06002.06002.2 8.89E-05 24-Nov K.VAPAQPSEEGPGR.K "sp|P23588|IF4B_HUMAN,tr|E7EX17|E7EX17_HUMAN" 2 1293.6313 2.7 76879 6002 2 1293.630906 647.8229 Eukaryotic translation initiation factor 4B OS=Homo sapiens OX=9606 GN=EIF4B PE=1 SV=2 4.53 1567.3 - 1.04E+06 - - - -0.327 - 1.794 0.45 - 227.6 1 2 0 -0.0004 13 0 0 0 4.40E+08 1.63E+08 - - - 3.8646 0.9996 221125_WJC_METTL3_EV_vs_WT_F06.06003.06003.2 7.58E-05 13/26 K.AVASSPAATNSEVK.M sp|Q9P1Y5|CAMP3_HUMAN 1 1330.6729 2.2 76880 6003 2 1330.676251 666.3437 Calmodulin-regulated spectrin-associated protein 3 OS=Homo sapiens OX=9606 GN=CAMSAP3 PE=1 SV=2 6.05 1567.5 - 663232 - - - 2.5491 - 2.437 0.461 - 507.1 1 2 0 0.0034 14 0 0 0 4.66E+07 2.12E+07 - - - 4.6802 0.9999 221125_WJC_METTL3_EV_vs_WT_F06.06009.06009.3 0.0023 Nov-40 R.GHLENNPALEK.L "sp|Q8NHW5|RLA0L_HUMAN,sp|P05388|RLA0_HUMAN,tr|G3V210|G3V210_HUMAN,tr|F8VU65|F8VU65_HUMAN,tr|F8VWV4|F8VWV4_HUMAN,tr|F8VWS0|F8VWS0_HUMAN,tr|F8VS58|F8VS58_HUMAN,tr|F8VW21|F8VW21_HUMAN,tr|F8VZS0|F8VZS0_HUMAN,tr|F8VRK7|F8VRK7_HUMAN,tr|F8VQY6|F8VQY6_HUMAN,tr|F8VPE8|F8VPE8_HUMAN" 12 1220.6149 1.23 76884 6009 3 1220.613523 407.8789 60S acidic ribosomal protein P0-like OS=Homo sapiens OX=9606 GN=RPLP0P6 PE=5 SV=1 5.4 1568.1 - 2.55E+06 - - - -1.1691 - 2.316 0.408 - 230.1 1 2 0 -0.0014 11 0 0 0 2.11E+09 1.71E+09 - - - 5.4742 0.9984 221125_WJC_METTL3_EV_vs_WT_F06.06010.06010.3 0.137 Nov-36 K.NC[160.03]VAIAADRR.F "sp|P49720|PSB3_HUMAN,tr|A0A087WXQ8|A0A087WXQ8_HUMAN,tr|A0A087WUL2|A0A087WUL2_HUMAN,tr|A0A087WY10|A0A087WY10_HUMAN" 4 1144.5771 0.49 76885 6010 3 1144.575186 382.533 Proteasome subunit beta type-3 OS=Homo sapiens OX=9606 GN=PSMB3 PE=1 SV=2 8.25 1568.1 - 1.38E+06 - - - -1.6941 - 1.951 0.247 - 206.8 1 2 0 -0.0019 10 0 0 0 1.89E+07 3.83E+07 - - - 3.2451 0.9693 221125_WJC_METTL3_EV_vs_WT_F06.06016.06016.2 1.9 14-Jun R.TSIEVGVK.G sp|Q03052|PO3F1_HUMAN 1 831.4702 9870.73 76889 6016 2 831.4696 416.7424 "POU domain, class 3, transcription factor 1 OS=Homo sapiens OX=9606 GN=POU3F1 PE=2 SV=3" 5.66 1568.8 - 3.35E+06 - - - -0.7012 - 1.094 0.112 - 126.8 3 2 0 -0.0006 8 0 0 0 9.79E+09 9.91E+05 - - - -0.0741 0.9889 221125_WJC_METTL3_EV_vs_WT_F06.06023.06023.3 0.224 Nov-44 R.VAAAPASGALRR.L "sp|P06576|ATPB_HUMAN,tr|F8W079|F8W079_HUMAN,tr|F8W0P7|F8W0P7_HUMAN,tr|H0YH81|H0YH81_HUMAN" 4 1138.6571 0.02 76894 6023 3 1138.657211 380.5596 "ATP synthase subunit beta, mitochondrial OS=Homo sapiens OX=9606 GN=ATP5F1B PE=1 SV=3" 12 1569.5 - 1.05E+06 - - - 0.1063 - 1.772 0.145 - 132.2 1 2 0 0.0001 12 0 0 0 7.22E+07 3.11E+09 - - - 1.7424 0.9978 221125_WJC_METTL3_EV_vs_WT_F06.06025.06025.3 0.0215 Oct-36 K.AVQVHQDTLR[166.11].T "sp|Q9UKV8|AGO2_HUMAN,sp|Q9UL18|AGO1_HUMAN,tr|A0A6I8PTZ8|A0A6I8PTZ8_HUMAN,tr|Q5TA58|Q5TA58_HUMAN" 4 1175.6286 1.78 76896 6025 3 1175.630172 392.8835 Protein argonaute-2 OS=Homo sapiens OX=9606 GN=AGO2 PE=1 SV=3 6.79 1569.7 - 564519 - - - 1.3031 - 1.938 0.22 - 184 1 2 0 0.0015 10 0 0 0 2.15E+08 1.21E+08 - - - 2.9247 0.9999 221125_WJC_METTL3_EV_vs_WT_F06.06030.06030.2 2.21E-05 18-Oct K.GGGSVC[160.03]PVC[160.03]R.Q sp|P19474|RO52_HUMAN 1 1047.459 1.87 76899 6030 2 1047.458239 524.7368 E3 ubiquitin-protein ligase TRIM21 OS=Homo sapiens OX=9606 GN=TRIM21 PE=1 SV=1 8.07 1570.4 - 5.97E+06 - - - -0.7112 - 2.202 0.501 - 407.9 1 2 0 -0.0007 10 0 0 0 3.03E+08 1.63E+08 - - - 4.9445 0.9996 221125_WJC_METTL3_EV_vs_WT_F06.06031.06031.2 0.000901 14-Sep K.NAQLELKK.S "sp|Q99615|DNJC7_HUMAN,tr|A0A6I8PRZ0|A0A6I8PRZ0_HUMAN,tr|A0A6I8PR89|A0A6I8PR89_HUMAN,tr|A0A6I8PIK4|A0A6I8PIK4_HUMAN,tr|A0A6I8PS32|A0A6I8PS32_HUMAN,tr|A0A6I8PUD4|A0A6I8PUD4_HUMAN,tr|K7ER44|K7ER44_HUMAN,tr|A0A6I8PU73|A0A6I8PU73_HUMAN" 8 942.5498 0.66 76900 6031 2 942.548747 472.2822 DnaJ homolog subfamily C member 7 OS=Homo sapiens OX=9606 GN=DNAJC7 PE=1 SV=2 8.59 1570.4 - 2.07E+06 - - - -1.1501 - 1.829 0.35 - 309.7 1 2 0 -0.0011 8 0 0 0 3.64E+07 5.48E+07 - - - 3.4467 0.9999 221125_WJC_METTL3_EV_vs_WT_F06.06036.06036.2 5.63E-07 22-Sep R.SYGATATSPGER[166.11].F sp|Q8TB61|S35B2_HUMAN 1 1205.5552 1 76903 6036 2 1205.55457 603.7849 Adenosine 3'-phospho 5'-phosphosulfate transporter 1 OS=Homo sapiens OX=9606 GN=SLC35B2 PE=1 SV=1 5.72 1571.1 - 1.15E+06 - - - -0.5226 - 2.089 0.588 - 198.1 1 2 0 -0.0006 12 0 0 0 9.70E+07 9.72E+07 - - - 5.3221 1 221125_WJC_METTL3_EV_vs_WT_F06.06037.06037.2 3.56E-08 22-Dec R.SYGATATSPGER.F sp|Q8TB61|S35B2_HUMAN 1 1195.5469 1.01 76904 6037 2 1195.548123 598.7807 Adenosine 3'-phospho 5'-phosphosulfate transporter 1 OS=Homo sapiens OX=9606 GN=SLC35B2 PE=1 SV=1 5.72 1571.2 - 1.26E+06 - - - 0.9979 - 2.309 0.651 - 461.1 1 2 0 0.0012 12 0 0 0 9.92E+07 9.86E+07 - - - 6.0507 0.9995 221125_WJC_METTL3_EV_vs_WT_F06.06038.06038.2 0.000574 16-Oct R.K[136.11]LLEGEETR[166.11].F "sp|Q16352|AINX_HUMAN,sp|P07197|NFM_HUMAN,sp|P07196|NFL_HUMAN,tr|E7ESP9|E7ESP9_HUMAN,tr|E7EMV2|E7EMV2_HUMAN" 5 1091.5942 2.11 76905 6038 2 1091.592739 546.8044 Alpha-internexin OS=Homo sapiens OX=9606 GN=INA PE=1 SV=2 4.79 1571.4 - 1.21E+06 - - - -1.2999 - 1.85 0.338 - 402.7 1 2 0 -0.0014 9 0 0 0 8.32E+07 3.95E+07 - - - 3.3168 0.9996 221125_WJC_METTL3_EV_vs_WT_F06.06044.06044.2 0.00481 16-Oct K.MAIQTQQSK.F "sp|O96008|TOM40_HUMAN,tr|K7EKG4|K7EKG4_HUMAN,tr|K7EJ57|K7EJ57_HUMAN" 3 1033.5226 1.06 76910 6044 2 1033.521515 517.7686 Mitochondrial import receptor subunit TOM40 homolog OS=Homo sapiens OX=9606 GN=TOMM40 PE=1 SV=1 8.5 1571.9 - 7.24E+06 - - - -1.0788 - 1.955 0.343 - 410.6 1 2 0 -0.0011 9 0 0 0 3.90E+08 3.69E+08 - - - 3.5135 0.9997 221125_WJC_METTL3_EV_vs_WT_F06.06047.06047.2 0.000346 24-Dec K.VAPAQPSEEGPGR[166.11].K "sp|P23588|IF4B_HUMAN,tr|E7EX17|E7EX17_HUMAN" 2 1303.6396 2.72 76913 6047 2 1303.638206 652.8271 Eukaryotic translation initiation factor 4B OS=Homo sapiens OX=9606 GN=EIF4B PE=1 SV=2 4.53 1572.2 - 1.10E+06 - - - -1.0685 - 1.862 0.437 - 220.3 1 2 0 -0.0014 13 0 0 0 4.62E+08 1.70E+08 - - - 3.8637 0.8703 221125_WJC_METTL3_EV_vs_WT_F06.06048.06048.2 4.75 16-Jul K.R[166.11]LEEPEEPK[136.11].V sp|O75822|EIF3J_HUMAN 1 1143.5891 0.43 76914 6048 2 1143.591237 572.8018 Eukaryotic translation initiation factor 3 subunit J OS=Homo sapiens OX=9606 GN=EIF3J PE=1 SV=2 4.49 1572.4 - 929661 - - - 1.8923 - 1.228 0.015 - 102.9 6 2 0 0.0022 9 0 0 0 1.55E+07 3.58E+07 - - - -0.6023 0.9743 221125_WJC_METTL3_EV_vs_WT_F06.06049.06049.2 0.209 22-Jul R.VAAAPASGALRR.L "sp|P06576|ATPB_HUMAN,tr|F8W079|F8W079_HUMAN,tr|F8W0P7|F8W0P7_HUMAN,tr|H0YH81|H0YH81_HUMAN" 4 1138.6571 7.69 76915 6049 2 1138.655734 570.3358 "ATP synthase subunit beta, mitochondrial OS=Homo sapiens OX=9606 GN=ATP5F1B PE=1 SV=3" 12 1572.5 - 524157 - - - -1.1909 - 1.583 0.054 - 64.1 12 2 0 -0.0014 12 0 0 0 1.21E+07 1.58E+06 - - - 0.1659 0.9993 221125_WJC_METTL3_EV_vs_WT_F06.06052.06052.2 0.0274 16-Sep K.MAIQTQQSK[136.11].F "sp|O96008|TOM40_HUMAN,tr|K7EKG4|K7EKG4_HUMAN,tr|K7EJ57|K7EJ57_HUMAN" 3 1041.5368 1.06 76916 6052 2 1041.535299 521.7757 Mitochondrial import receptor subunit TOM40 homolog OS=Homo sapiens OX=9606 GN=TOMM40 PE=1 SV=1 8.5 1572.9 - 1.15E+07 - - - -1.4699 - 1.83 0.321 - 314.9 1 2 0 -0.0015 9 0 0 0 3.90E+08 3.69E+08 - - - 3.1597 0.9999 221125_WJC_METTL3_EV_vs_WT_F06.06054.06054.2 3.43E-05 18-Nov K.GGGSVC[160.03]PVC[160.03]R[166.11].Q sp|P19474|RO52_HUMAN 1 1057.4673 1.89 76917 6054 2 1057.466074 529.7409 E3 ubiquitin-protein ligase TRIM21 OS=Homo sapiens OX=9606 GN=TRIM21 PE=1 SV=1 8.07 1573.1 - 7.55E+06 - - - -1.1159 - 2.356 0.542 - 524.4 1 2 0 -0.0012 10 0 0 0 3.03E+08 1.60E+08 - - - 5.4359 0.9919 221125_WJC_METTL3_EV_vs_WT_F06.06055.06055.2 0.000138 18-Nov N.STGGFDGQAR.Q sp|Q96PK6|RBM14_HUMAN 1 994.4468 2.06 76918 6055 2 994.446979 498.2307 RNA-binding protein 14 OS=Homo sapiens OX=9606 GN=RBM14 PE=1 SV=2 5.55 1573.2 - 1.90E+06 - - - 0.1579 - 2.023 0.497 - 548.8 1 1 0 0.0002 10 0 0 0 1.21E+08 5.88E+07 - - - 4.6785 0.9946 221125_WJC_METTL3_EV_vs_WT_F06.06059.06059.2 0.163 16-Aug R.SQQTLDTPK[136.11].T "sp|Q5T6F2|UBAP2_HUMAN,tr|H0YDN2|H0YDN2_HUMAN" 2 1024.528 2.42 76920 6059 2 1024.527199 513.2713 Ubiquitin-associated protein 2 OS=Homo sapiens OX=9606 GN=UBAP2 PE=1 SV=1 5.55 1573.7 - 2.41E+06 - - - -0.8199 - 1.3 0.179 - 166.6 1 2 0 -0.0008 9 0 0 0 1.84E+08 7.61E+07 - - - 1.1219 0.9985 221125_WJC_METTL3_EV_vs_WT_F06.06063.06063.2 0.00669 18-Jun R.GGDPEDNDIR.E sp|O60476|MA1A2_HUMAN 1 1086.4578 0.76 76922 6063 2 1086.459262 544.2362 "Mannosyl-oligosaccharide 1,2-alpha-mannosidase IB OS=Homo sapiens OX=9606 GN=MAN1A2 PE=1 SV=1" 3.84 1574.1 - 1.60E+06 - - - 1.3631 - 1.272 0.363 - 89.8 1 2 0 0.0015 10 0 0 0 4.07E+07 5.37E+07 - - - 2.3932 0.9706 221125_WJC_METTL3_EV_vs_WT_F06.06064.06064.2 1.83 16-Jul R.SAVPPGADK.K "sp|P46783|RS10_HUMAN,tr|F6U211|F6U211_HUMAN,tr|A0A1W2PQS6|A0A1W2PQS6_HUMAN,tr|A0A2R8YFH6|A0A2R8YFH6_HUMAN,tr|A0A2R8Y7H1|A0A2R8Y7H1_HUMAN,tr|S4R435|S4R435_HUMAN" 6 840.4341 0.3 76923 6064 2 840.432691 421.2243 40S ribosomal protein S10 OS=Homo sapiens OX=9606 GN=RPS10 PE=1 SV=1 5.55 1574.3 - 412527 - - - -1.7146 - 1.278 0.071 - 123 1 2 0 -0.0014 9 0 0 0 2.88E+07 9.67E+07 - - - 0.2746 0.9988 221125_WJC_METTL3_EV_vs_WT_F06.06066.06066.2 0.00417 18-Sep K.AQQELEEQTR[166.11].R sp|P26038|MOES_HUMAN 1 1240.5923 2.66 76925 6066 2 1240.596716 621.3034 Moesin OS=Homo sapiens OX=9606 GN=MSN PE=1 SV=3 4.25 1574.5 - 291644 - - - 3.5483 - 2.124 0.421 - 495.1 1 2 0 0.0044 10 0 0 0 3.52E+08 1.32E+08 - - - 4.2518 0.9948 221125_WJC_METTL3_EV_vs_WT_F06.06072.06072.2 0.674 16-Sep K.RVPLTPQEK.R sp|Q86SF2|GALT7_HUMAN 1 1066.6135 1.92 76927 6072 2 1066.611914 534.314 N-acetylgalactosaminyltransferase 7 OS=Homo sapiens OX=9606 GN=GALNT7 PE=1 SV=1 8.75 1575.3 - 1.43E+06 - - - -1.4813 - 1.602 0.132 - 316 1 2 0 -0.0016 9 0 0 0 1.02E+08 5.30E+07 - - - 1.3788 0.9997 221125_WJC_METTL3_EV_vs_WT_F06.06073.06073.2 6.77E-05 18-Sep R.GGDPEDNDIR[166.11].E sp|O60476|MA1A2_HUMAN 1 1096.4661 1.07 76928 6073 2 1096.463679 549.2403 "Mannosyl-oligosaccharide 1,2-alpha-mannosidase IB OS=Homo sapiens OX=9606 GN=MAN1A2 PE=1 SV=1" 3.84 1575.5 - 813670 - - - -2.1633 - 2.051 0.55 - 316.5 1 2 0 -0.0024 10 0 0 0 3.96E+07 3.71E+07 - - - 5.1076 0.9575 221125_WJC_METTL3_EV_vs_WT_F06.06074.06074.2 2.75 20-Aug K.LQSLDGPGAHK[136.11].E sp|Q6ZRP7|QSOX2_HUMAN 1 1129.5971 1.17 76929 6074 2 1129.595161 565.8058 Sulfhydryl oxidase 2 OS=Homo sapiens OX=9606 GN=QSOX2 PE=1 SV=3 6.74 1575.6 - 477962 - - - -1.736 - 1.245 0.055 - 115.7 1 2 0 -0.002 11 0 0 0 1.45E+07 1.24E+07 - - - 0.0394 0.9996 221125_WJC_METTL3_EV_vs_WT_F06.06085.06085.2 4.22E-05 24-Oct R.GAGSIAGASASPK.E sp|P15924|DESP_HUMAN 1 1072.5513 10.48 76934 6085 2 1072.54984 537.2829 Desmoplakin OS=Homo sapiens OX=9606 GN=DSP PE=1 SV=3 8.75 1576.9 - 3.39E+06 - - - -1.3491 - 1.886 0.398 - 366.5 1 2 0 -0.0014 13 0 0 0 2.98E+08 2.84E+07 - - - 3.6085 0.8995 221125_WJC_METTL3_EV_vs_WT_F06.06090.06090.2 1.5 14-Aug R.DKIIVNDR.Q sp|Q9Y3I0|RTCB_HUMAN 1 971.54 2.58 76937 6090 2 971.539769 486.7773 RNA-splicing ligase RtcB homolog OS=Homo sapiens OX=9606 GN=RTCB PE=1 SV=1 5.96 1577.6 - 777922 - - - -0.2316 - 1.764 0.001 - 292 2 2 1 -0.0002 8 0 0 0 2.54E+08 9.84E+07 - - - 0.6257 0.9993 221125_WJC_METTL3_EV_vs_WT_F06.06093.06093.2 0.00409 14-Jul R.SYVTTSTR.T "sp|P08670|VIME_HUMAN,tr|B0YJC4|B0YJC4_HUMAN,tr|A0A1B0GVG8|A0A1B0GVG8_HUMAN,tr|A0A1B0GTT5|A0A1B0GTT5_HUMAN" 4 913.4505 1.63 76938 6093 2 913.449269 457.7325 Vimentin OS=Homo sapiens OX=9606 GN=VIM PE=1 SV=4 8.46 1577.9 - 6.85E+06 - - - -1.3597 - 1.329 0.417 - 167.2 1 2 0 -0.0012 8 0 0 0 2.44E+08 1.50E+08 - - - 2.9784 0.9998 221125_WJC_METTL3_EV_vs_WT_F06.06095.06095.2 9.35E-05 18-Oct K.GGDC[160.03]LTSQTR.L "sp|Q8IXB1|DJC10_HUMAN,tr|A0A7P0Z4F2|A0A7P0Z4F2_HUMAN,tr|A0A7P0Z431|A0A7P0Z431_HUMAN,tr|H7C1G0|H7C1G0_HUMAN,tr|A0A7P0TAQ9|A0A7P0TAQ9_HUMAN,tr|A0A494C1G5|A0A494C1G5_HUMAN" 6 1093.4822 1.53 76940 6095 2 1093.483298 547.7484 DnaJ homolog subfamily C member 10 OS=Homo sapiens OX=9606 GN=DNAJC10 PE=1 SV=2 5.83 1578.2 - 642688 - - - 0.984 - 1.862 0.5 - 421.8 1 2 0 0.0011 10 0 0 0 4.12E+07 2.70E+07 - - - 4.4689 0.9402 221125_WJC_METTL3_EV_vs_WT_F06.06096.06096.2 2.87 16-Aug K.C[160.03]QEC[160.03]NNVIK[136.11].T "sp|O14628|ZN195_HUMAN,tr|E9PIY8|E9PIY8_HUMAN,tr|A0A087WT67|A0A087WT67_HUMAN" 3 1171.5205 0.26 76941 6096 2 1171.517287 586.7675 Zinc finger protein 195 OS=Homo sapiens OX=9606 GN=ZNF195 PE=1 SV=2 5.99 1578.3 - 489528 - - - -2.7665 - 1.099 0.131 - 172.2 1 2 0 -0.0032 9 0 0 0 3.90E+06 1.48E+07 - - - 0.2807 0.8706 221125_WJC_METTL3_EV_vs_WT_F06.06097.06097.2 0.0923 18-Aug K.AYISSDQQEK[136.11].R "sp|Q8WYA0|IFT81_HUMAN,tr|H0YHE2|H0YHE2_HUMAN" 2 1175.555 0.77 76942 6097 2 1175.548446 588.7848 Intraflagellar transport protein 81 homolog OS=Homo sapiens OX=9606 GN=IFT81 PE=1 SV=1 4.37 1578.5 - 338268 - - - -5.5599 - 1.227 0.199 - 208.7 1 2 0 -0.0065 10 0 0 0 9.33E+06 1.22E+07 - - - 1.0798 0.999 221125_WJC_METTL3_EV_vs_WT_F06.06099.06099.2 0.0769 14-Jun R.RPFDPNDR.C "sp|Q16629|SRSF7_HUMAN,tr|C9JAB2|C9JAB2_HUMAN,tr|F8WEA1|F8WEA1_HUMAN,tr|A0A0B4J1Z1|A0A0B4J1Z1_HUMAN" 4 1015.4835 1.05 76943 6099 2 1015.482252 508.749 Serine\arginine-rich splicing factor 7 OS=Homo sapiens OX=9606 GN=SRSF7 PE=1 SV=1 5.96 1578.7 - 5.57E+06 - - - -1.2703 - 1.532 0.314 - 166.1 1 2 0 -0.0013 8 0 0 0 3.44E+08 3.29E+08 - - - 2.6463 0.9888 221125_WJC_METTL3_EV_vs_WT_F06.06101.06101.2 0.00726 14-Jun K.EVSTYIK[136.11]K[136.11].L "sp|P68104|EF1A1_HUMAN,sp|Q5VTE0|EF1A3_HUMAN,tr|A0A7I2V659|A0A7I2V659_HUMAN,tr|A0A7I2V3H3|A0A7I2V3H3_HUMAN,tr|A0A7I2V5N4|A0A7I2V5N4_HUMAN,tr|A0A087WVQ9|A0A087WVQ9_HUMAN,tr|A0A087WV01|A0A087WV01_HUMAN" 7 982.567 0.07 76944 6101 2 982.566907 492.2908 Elongation factor 1-alpha 1 OS=Homo sapiens OX=9606 GN=EEF1A1 PE=1 SV=1 8.59 1578.9 - 1.21E+07 - - - -0.0916 - 1.338 0.084 - 135.5 1 2 0 -0.0001 8 0 0 0 6.02E+07 8.63E+08 - - - 0.5396 0.985 221125_WJC_METTL3_EV_vs_WT_F06.06102.06102.3 0.0848 Sep-32 R.LFC[160.03]TDKNER.V sp|Q9UKV8|AGO2_HUMAN 1 1181.5499 1.98 76945 6102 3 1181.548435 394.8572 Protein argonaute-2 OS=Homo sapiens OX=9606 GN=AGO2 PE=1 SV=3 6.06 1579 - 712733 - - - -1.2458 - 1.609 0.246 - 87.4 2 2 1 -0.0015 9 0 0 0 4.15E+07 2.09E+07 - - - 2.5763 0.9968 221125_WJC_METTL3_EV_vs_WT_F06.06110.06110.2 0.0412 18-Sep R.EMQQLSGGQK[136.11].S sp|Q9UQE7|SMC3_HUMAN 1 1112.5376 0.61 76948 6110 2 1112.536448 557.2761 Structural maintenance of chromosomes protein 3 OS=Homo sapiens OX=9606 GN=SMC3 PE=1 SV=2 6.1 1580 - 1.05E+06 - - - -0.9977 - 1.302 0.243 - 141.1 1 2 0 -0.0011 10 0 0 0 2.70E+07 4.46E+07 - - - 1.5721 0.9993 221125_WJC_METTL3_EV_vs_WT_F06.06112.06112.2 0.0131 18-Oct K.TDDSTSGLTR.S "sp|Q9HAW4|CLSPN_HUMAN,tr|E7ESG2|E7ESG2_HUMAN" 2 1051.4782 0.53 76950 6112 2 1051.47906 526.7464 Claspin OS=Homo sapiens OX=9606 GN=CLSPN PE=1 SV=3 4.21 1580.2 - 1.20E+06 - - - 0.835 - 1.703 0.326 - 244.8 1 2 0 0.0009 10 0 0 0 4.65E+07 8.81E+07 - - - 2.9346 0.9995 221125_WJC_METTL3_EV_vs_WT_F06.06116.06116.2 0.000172 26-Oct K.LGASNSPGQPNSVK[136.11].R sp|P49756|RBM25_HUMAN 1 1362.6983 0.72 76952 6116 2 1362.70124 682.3564 RNA-binding protein 25 OS=Homo sapiens OX=9606 GN=RBM25 PE=1 SV=3 8.75 1580.7 - 285803 - - - 2.1626 - 1.991 0.467 - 133.1 1 2 0 0.0029 14 0 0 0 3.14E+07 4.35E+07 - - - 4.2174 0.9343 221125_WJC_METTL3_EV_vs_WT_F06.06119.06119.2 0.000834 12-Jun C.FHMDTC[160.03]K[136.11].Y "sp|Q86U44|MTA70_HUMAN,tr|H0YFV6|H0YFV6_HUMAN" 2 945.3928 0.03 76953 6119 2 945.392406 473.7037 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 6.73 1581.1 - 2.51E+06 - - - -0.4252 - 1.432 0.28 - 250.6 1 1 0 -0.0004 7 0 0 0 4.44E+07 1.69E+09 - - - 2.2467 0.9998 221125_WJC_METTL3_EV_vs_WT_F06.06120.06120.2 0.0043 26-Oct K.LGASNSPGQPNSVK.R sp|P49756|RBM25_HUMAN 1 1354.6841 0.72 76954 6120 2 1354.682589 678.3493 RNA-binding protein 25 OS=Homo sapiens OX=9606 GN=RBM25 PE=1 SV=3 8.75 1581.3 - 256173 - - - -1.1102 - 2.189 0.428 - 217.3 1 2 0 -0.0015 14 0 0 0 3.14E+07 4.35E+07 - - - 4.1678 0.9998 221125_WJC_METTL3_EV_vs_WT_F06.06125.06125.2 0.00121 20-Aug R.GGNGLAPGEDR.F "sp|Q86SF2|GALT7_HUMAN,tr|E9PBY3|E9PBY3_HUMAN" 2 1041.4839 3.59 76956 6125 2 1041.483759 521.7492 N-acetylgalactosaminyltransferase 7 OS=Homo sapiens OX=9606 GN=GALNT7 PE=1 SV=1 4.37 1581.9 - 899020 - - - -0.1699 - 1.675 0.465 - 163.2 1 2 0 -0.0002 11 0 0 0 2.63E+07 7.33E+06 - - - 3.8708 0.9895 221125_WJC_METTL3_EV_vs_WT_F06.06128.06128.2 0.000106 22-Nov R.VANTSTQTMGPR.P "sp|P11940|PABP1_HUMAN,tr|H0YAS6|H0YAS6_HUMAN,tr|H0YB75|H0YB75_HUMAN,tr|A0A7I2YQE4|A0A7I2YQE4_HUMAN,tr|H0YAW6|H0YAW6_HUMAN,tr|A0A7I2V649|A0A7I2V649_HUMAN,tr|E7ERJ7|E7ERJ7_HUMAN,tr|A0A7I2YQ88|A0A7I2YQ88_HUMAN,tr|A0A087WTT1|A0A087WTT1_HUMAN,tr|A0A7I2YQ90|A0A7I2YQ90_HUMAN,tr|A0A7I2V4N4|A0A7I2V4N4_HUMAN,tr|E7EQV3|E7EQV3_HUMAN" 12 1261.6085 1.69 76958 6128 2 1261.610675 631.8115 Polyadenylate-binding protein 1 OS=Homo sapiens OX=9606 GN=PABPC1 PE=1 SV=2 9.72 1582.3 - 276360 - - - 1.7359 - 2.428 0.556 - 621.7 1 1 0 0.0022 12 0 0 0 3.74E+07 2.21E+07 - - - 5.481 0.9942 221125_WJC_METTL3_EV_vs_WT_F06.06130.06130.2 0.53 14-Jul R.SEVTELRR.V "sp|P08779|K1C16_HUMAN,tr|K7ENW6|K7ENW6_HUMAN" 2 988.5302 6.58 76959 6130 2 988.529949 495.2724 "Keratin, type I cytoskeletal 16 OS=Homo sapiens OX=9606 GN=KRT16 PE=1 SV=4" 5.86 1582.5 - 1.72E+07 - - - -0.2114 - 1.314 0.152 - 108.2 1 2 0 -0.0002 8 0 0 0 5.93E+09 9.02E+08 - - - 0.9872 0.9991 221125_WJC_METTL3_EV_vs_WT_F06.06132.06132.2 0.0429 16-Sep K.TIAPQNAPR[166.11].D "sp|Q9NYF8|BCLF1_HUMAN,tr|H0YF00|H0YF00_HUMAN,tr|E9PKI6|E9PKI6_HUMAN,tr|A0A1W2PQ43|A0A1W2PQ43_HUMAN,tr|E9PK91|E9PK91_HUMAN,tr|E9PJA7|E9PJA7_HUMAN,tr|E9PK09|E9PK09_HUMAN,tr|E9PQN2|E9PQN2_HUMAN" 8 976.5329 2.43 76960 6132 2 976.532764 489.2738 Bcl-2-associated transcription factor 1 OS=Homo sapiens OX=9606 GN=BCLAF1 PE=1 SV=2 9.41 1582.7 - 5.24E+06 - - - -0.1894 - 1.683 0.26 - 241.8 1 2 0 -0.0002 9 0 0 0 1.13E+09 4.64E+08 - - - 2.4674 0.9166 221125_WJC_METTL3_EV_vs_WT_F06.06133.06133.2 1.33 14-Jun R.FTHIPSGK.C "sp|Q86SF2|GALT7_HUMAN,tr|H0YAH3|H0YAH3_HUMAN" 2 885.4709 0.99 76961 6133 2 885.468994 443.7427 N-acetylgalactosaminyltransferase 7 OS=Homo sapiens OX=9606 GN=GALNT7 PE=1 SV=1 8.76 1582.8 - 1.11E+06 - - - -2.0983 - 1.091 0.078 - 161.6 2 2 0 -0.0019 8 0 0 0 4.54E+07 4.60E+07 - - - -0.2553 0.9941 221125_WJC_METTL3_EV_vs_WT_F06.06147.06147.2 0.502 12-Jul R.KQEELLR.K "sp|Q6Y7W6|GGYF2_HUMAN,tr|A0A7I2V3H7|A0A7I2V3H7_HUMAN,tr|I1E4Y6|I1E4Y6_HUMAN,tr|A0A7I2V516|A0A7I2V516_HUMAN,tr|A0A7I2V3H0|A0A7I2V3H0_HUMAN,tr|A0A7I2V361|A0A7I2V361_HUMAN,tr|E7ESB6|E7ESB6_HUMAN" 7 914.5185 2.63 76968 6147 2 914.517657 458.2665 GRB10-interacting GYF protein 2 OS=Homo sapiens OX=9606 GN=GIGYF2 PE=1 SV=1 6.14 1584.6 - 1.41E+06 - - - -0.9557 - 1.323 0.159 - 217.4 1 2 0 -0.0009 7 0 0 0 5.37E+07 2.04E+07 - - - 1.102 0.9976 221125_WJC_METTL3_EV_vs_WT_F06.06149.06149.2 0.162 16-Aug R.DLENGSHIR[166.11].G "sp|P25205|MCM3_HUMAN,tr|J3KQ69|J3KQ69_HUMAN,tr|A0A499FHX9|A0A499FHX9_HUMAN" 3 1049.5129 0.58 76970 6149 2 1049.511433 525.7637 DNA replication licensing factor MCM3 OS=Homo sapiens OX=9606 GN=MCM3 PE=1 SV=3 5.32 1584.8 - 982822 - - - -1.4369 - 1.224 0.317 - 199.5 1 2 0 -0.0015 9 0 0 0 2.80E+07 4.86E+07 - - - 1.9666 0.9976 221125_WJC_METTL3_EV_vs_WT_F06.06155.06155.2 0.00248 20-Aug K.VAVTEGC[160.03]QPSR[166.11].V "sp|O75369|FLNB_HUMAN,tr|E7EN95|E7EN95_HUMAN,tr|A0A804HK76|A0A804HK76_HUMAN,tr|A0A804HL72|A0A804HL72_HUMAN" 4 1212.5796 2.28 76974 6155 2 1212.584172 607.2971 Filamin-B OS=Homo sapiens OX=9606 GN=FLNB PE=1 SV=2 5.97 1585.6 - 150815 - - - 3.7367 - 1.811 0.392 - 239.2 1 2 0 0.0045 11 0 0 0 1.26E+08 5.52E+07 - - - 3.5415 0.9735 221125_WJC_METTL3_EV_vs_WT_F06.06164.06164.2 0.217 20-Jul R.AALQEEEQASK.Q "sp|O00139|KIF2A_HUMAN,tr|A0A6Q8PFA6|A0A6Q8PFA6_HUMAN,tr|A0A6Q8PGG1|A0A6Q8PGG1_HUMAN,tr|A0A6Q8PGH7|A0A6Q8PGH7_HUMAN,tr|A0A6Q8PG37|A0A6Q8PG37_HUMAN,tr|A0A6Q8PH57|A0A6Q8PH57_HUMAN" 6 1202.5779 2.5 76979 6164 2 1202.576574 602.2962 Kinesin-like protein KIF2A OS=Homo sapiens OX=9606 GN=KIF2A PE=1 SV=3 4.25 1586.7 - 401630 - - - -1.0993 - 1.465 0.006 - 100.7 1 2 0 -0.0013 11 0 0 0 1.27E+08 5.08E+07 - - - 0.1179 0.8974 221125_WJC_METTL3_EV_vs_WT_F06.06166.06166.2 5.98 12-May K.HLFENSR.L "sp|Q8NBU5|ATAD1_HUMAN,tr|A0A7P0TAM5|A0A7P0TAM5_HUMAN,tr|A0A7P0T9B4|A0A7P0T9B4_HUMAN,tr|A0A7P0Z4J1|A0A7P0Z4J1_HUMAN,tr|A0A7P0T7Z9|A0A7P0T7Z9_HUMAN,tr|A0A7P0T9U2|A0A7P0T9U2_HUMAN" 6 901.4406 0.5 76981 6166 2 901.439821 451.7276 Outer mitochondrial transmembrane helix translocase OS=Homo sapiens OX=9606 GN=ATAD1 PE=1 SV=1 6.75 1586.8 - 1.13E+06 - - - -0.8808 - 0.998 0.018 - 88 1 2 0 -0.0008 7 0 0 0 7.29E+07 1.47E+08 - - - -0.8326 0.9997 221125_WJC_METTL3_EV_vs_WT_F06.06170.06170.2 1.88E-05 18-Nov R.VDVADQAQDK.D "sp|P23588|IF4B_HUMAN,tr|E7EX17|E7EX17_HUMAN,tr|F8VSC7|F8VSC7_HUMAN,tr|F8VYE9|F8VYE9_HUMAN,tr|F8VX11|F8VX11_HUMAN,tr|F8W0K0|F8W0K0_HUMAN,tr|F8VP89|F8VP89_HUMAN" 7 1087.5146 2.53 76984 6170 2 1087.513255 544.7646 Eukaryotic translation initiation factor 4B OS=Homo sapiens OX=9606 GN=EIF4B PE=1 SV=2 3.93 1587.3 - 2.42E+06 - - - -1.2073 - 2.302 0.376 - 535.1 1 2 0 -0.0013 10 0 0 0 9.86E+07 3.90E+07 - - - 4.1451 0.9997 221125_WJC_METTL3_EV_vs_WT_F06.06173.06173.2 0.00369 20-Sep R.AALQEEEQASK[136.11].Q "sp|O00139|KIF2A_HUMAN,tr|A0A6Q8PFA6|A0A6Q8PFA6_HUMAN,tr|A0A6Q8PGG1|A0A6Q8PGG1_HUMAN,tr|A0A6Q8PGH7|A0A6Q8PGH7_HUMAN,tr|A0A6Q8PG37|A0A6Q8PG37_HUMAN,tr|A0A6Q8PH57|A0A6Q8PH57_HUMAN" 6 1210.5921 2.5 76985 6173 2 1210.593124 606.3033 Kinesin-like protein KIF2A OS=Homo sapiens OX=9606 GN=KIF2A PE=1 SV=3 4.25 1587.7 - 283670 - - - 0.8492 - 2.066 0.375 - 233 1 2 0 0.001 11 0 0 0 1.27E+08 5.08E+07 - - - 3.7734 0.9981 221125_WJC_METTL3_EV_vs_WT_F06.06175.06175.2 0.277 16-Aug R.LSYNTASNK[136.11].T sp|P49207|RL34_HUMAN 1 1004.5018 0.8 76986 6175 2 1004.50118 503.2582 60S ribosomal protein L34 OS=Homo sapiens OX=9606 GN=RPL34 PE=1 SV=3 8.59 1587.9 - 1.46E+06 - - - -0.6411 - 1.5 0.226 - 163.7 1 2 0 -0.0006 9 0 0 0 2.67E+08 3.34E+08 - - - 1.8831 0.9954 221125_WJC_METTL3_EV_vs_WT_F06.06186.06186.2 0.339 12-Jun K.HLFENSR[166.11].L "sp|Q8NBU5|ATAD1_HUMAN,tr|A0A7P0TAM5|A0A7P0TAM5_HUMAN,tr|A0A7P0T9B4|A0A7P0T9B4_HUMAN,tr|A0A7P0Z4J1|A0A7P0Z4J1_HUMAN,tr|A0A7P0T7Z9|A0A7P0T7Z9_HUMAN,tr|A0A7P0T9U2|A0A7P0T9U2_HUMAN" 6 911.4489 0.35 76991 6186 2 911.44826 456.7317 Outer mitochondrial transmembrane helix translocase OS=Homo sapiens OX=9606 GN=ATAD1 PE=1 SV=1 6.75 1589.3 - 1.26E+06 - - - -0.6857 - 1.219 0.21 - 114.1 1 2 0 -0.0006 7 0 0 0 9.69E+07 2.75E+08 - - - 1.2193 0.9996 221125_WJC_METTL3_EV_vs_WT_F06.06191.06191.2 0.00139 18-Aug K.QDTITEESEK[136.11].Q "sp|O94913|PCF11_HUMAN,tr|E9PKN0|E9PKN0_HUMAN,tr|E9PQ01|E9PQ01_HUMAN" 3 1186.5445 0.76 76993 6191 2 1186.543841 594.2795 Pre-mRNA cleavage complex 2 protein Pcf11 OS=Homo sapiens OX=9606 GN=PCF11 PE=1 SV=3 4 1590 - 283598 - - - -0.536 - 1.699 0.391 - 234.5 1 2 0 -0.0006 10 0 0 0 1.26E+07 1.65E+07 - - - 3.4082 0.9974 221125_WJC_METTL3_EV_vs_WT_F06.06197.06197.2 0.546 12-Sep K.QNLEIHR.K "sp|P78332|RBM6_HUMAN,sp|P98175|RBM10_HUMAN,tr|E9PGM9|E9PGM9_HUMAN" 3 908.4828 1.41 76996 6197 2 908.481613 455.2487 RNA-binding protein 6 OS=Homo sapiens OX=9606 GN=RBM6 PE=1 SV=5 6.75 1590.7 - 1.30E+06 - - - -1.322 - 1.76 0.139 - 477.9 1 2 0 -0.0012 7 0 0 0 1.47E+08 1.04E+08 - - - 1.8585 1 221125_WJC_METTL3_EV_vs_WT_F06.06200.06200.2 0.00161 13/18 K.KDVDGAYMTK.V sp|P04264|K2C1_HUMAN 1 1126.5329 1073.23 76998 6200 2 1126.532406 564.2737 "Keratin, type II cytoskeletal 1 OS=Homo sapiens OX=9606 GN=KRT1 PE=1 SV=6" 5.96 1591.1 - 1.31E+07 - - - -0.403 - 2.855 0.62 - 553.2 1 2 0 -0.0005 10 0 0 0 8.02E+08 7.47E+05 - - - 6.5485 0.9999 221125_WJC_METTL3_EV_vs_WT_F06.06203.06203.2 7.82E-06 24-Oct R.IEGDETSTEAATR[166.11].L "sp|P52434|RPAB3_HUMAN,tr|C9JLU1|C9JLU1_HUMAN" 2 1388.6295 1.19 77001 6203 2 1388.628534 695.322 "DNA-directed RNA polymerases I, II, and III subunit RPABC3 OS=Homo sapiens OX=9606 GN=POLR2H PE=1 SV=4" 4 1591.4 - 192649 - - - -0.687 - 2.201 0.577 - 349.9 1 2 0 -0.001 13 0 0 0 1.02E+08 8.53E+07 - - - 5.3272 0.9997 221125_WJC_METTL3_EV_vs_WT_F06.06207.06207.2 0.00236 18-Aug K.QDTITEESEK.Q "sp|O94913|PCF11_HUMAN,tr|E9PKN0|E9PKN0_HUMAN,tr|E9PQ01|E9PQ01_HUMAN" 3 1178.5303 0.76 77002 6207 2 1178.529921 590.2724 Pre-mRNA cleavage complex 2 protein Pcf11 OS=Homo sapiens OX=9606 GN=PCF11 PE=1 SV=3 4 1592 - 321489 - - - -0.3021 - 1.904 0.347 - 253.3 1 2 0 -0.0004 10 0 0 0 1.26E+07 1.65E+07 - - - 3.4013 0.9799 221125_WJC_METTL3_EV_vs_WT_F06.06211.06211.2 0.028 12-Jul C.FHMDTC[160.03]K.Y "sp|Q86U44|MTA70_HUMAN,tr|H0YFV6|H0YFV6_HUMAN" 2 937.3786 0.03 77004 6211 2 937.379225 469.6966 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 6.73 1592.4 - 737356 - - - 0.6582 - 1.191 0.54 - 187.2 1 1 0 0.0006 7 0 0 0 4.44E+07 1.69E+09 - - - 3.5831 1 221125_WJC_METTL3_EV_vs_WT_F06.06216.06216.2 2.55E-08 24-Nov R.IEGDETSTEAATR.L "sp|P52434|RPAB3_HUMAN,tr|C9JLU1|C9JLU1_HUMAN" 2 1378.6212 1.19 77006 6216 2 1378.61907 690.3179 "DNA-directed RNA polymerases I, II, and III subunit RPABC3 OS=Homo sapiens OX=9606 GN=POLR2H PE=1 SV=4" 4 1593.1 - 318627 - - - -1.5581 - 2.632 0.653 - 384.9 1 2 0 -0.0021 13 0 0 0 1.02E+08 8.53E+07 - - - 6.3471 0.9994 221125_WJC_METTL3_EV_vs_WT_F06.06220.06220.2 9.92E-05 18-Sep R.TPDGNLDQC[160.03]K[136.11].- sp|P30825|SL7A1_HUMAN 1 1154.5117 0.87 77008 6220 2 1154.508108 578.2631 High affinity cationic amino acid transporter 1 OS=Homo sapiens OX=9606 GN=SLC7A1 PE=1 SV=1 4.21 1593.5 - 240941 - - - -3.1442 - 1.858 0.553 - 356.5 1 2 0 -0.0036 10 0 0 0 3.89E+07 4.47E+07 - - - 4.8535 0.999 221125_WJC_METTL3_EV_vs_WT_F06.06226.06226.2 0.426 16-Sep R.KLLEGEEER.L "sp|P02545|LMNA_HUMAN,sp|P20700|LMNB1_HUMAN,sp|Q03252|LMNB2_HUMAN,tr|A0A804HL68|A0A804HL68_HUMAN,tr|Q5TCI8|Q5TCI8_HUMAN,tr|A0A6Q8PFJ0|A0A6Q8PFJ0_HUMAN,tr|A0A6Q8PHQ9|A0A6Q8PHQ9_HUMAN,tr|E9PBF6|E9PBF6_HUMAN,tr|Q3BDU5|Q3BDU5_HUMAN" 9 1101.5666 1.44 77011 6226 2 1101.566708 551.7906 Prelamin-A\C OS=Homo sapiens OX=9606 GN=LMNA PE=1 SV=1 4.49 1594.2 - 834964 - - - 0.0953 - 1.57 0.27 - 254.6 1 2 0 0.0001 9 0 0 0 4.85E+07 3.38E+07 - - - 2.3402 1 221125_WJC_METTL3_EV_vs_WT_F06.06228.06228.2 1.01E-06 14/20 R.GHLENNPALEK.L "sp|Q8NHW5|RLA0L_HUMAN,sp|P05388|RLA0_HUMAN,tr|G3V210|G3V210_HUMAN,tr|F8VU65|F8VU65_HUMAN,tr|F8VWV4|F8VWV4_HUMAN,tr|F8VWS0|F8VWS0_HUMAN,tr|F8VS58|F8VS58_HUMAN,tr|F8VW21|F8VW21_HUMAN,tr|F8VZS0|F8VZS0_HUMAN,tr|F8VRK7|F8VRK7_HUMAN,tr|F8VQY6|F8VQY6_HUMAN,tr|F8VPE8|F8VPE8_HUMAN" 12 1220.6149 1.23 77012 6228 2 1220.614138 611.3148 60S acidic ribosomal protein P0-like OS=Homo sapiens OX=9606 GN=RPLP0P6 PE=5 SV=1 5.4 1594.4 - 8.77E+06 - - - -0.6652 - 2.972 0.598 - 594.6 1 2 0 -0.0008 11 0 0 0 1.05E+09 8.53E+08 - - - 6.4042 0.9999 221125_WJC_METTL3_EV_vs_WT_F06.06229.06229.2 2.88E-09 20-Nov R.GHLENNPALEK[136.11].L "sp|Q8NHW5|RLA0L_HUMAN,sp|P05388|RLA0_HUMAN,tr|G3V210|G3V210_HUMAN,tr|F8VU65|F8VU65_HUMAN,tr|F8VWV4|F8VWV4_HUMAN,tr|F8VWS0|F8VWS0_HUMAN,tr|F8VS58|F8VS58_HUMAN,tr|F8VW21|F8VW21_HUMAN,tr|F8VZS0|F8VZS0_HUMAN,tr|F8VRK7|F8VRK7_HUMAN,tr|F8VQY6|F8VQY6_HUMAN,tr|F8VPE8|F8VPE8_HUMAN" 12 1228.6291 1.23 77013 6229 2 1228.62862 615.3219 60S acidic ribosomal protein P0-like OS=Homo sapiens OX=9606 GN=RPLP0P6 PE=5 SV=1 5.4 1594.4 - 6.24E+06 - - - -0.4314 - 2.555 0.417 - 327.6 1 2 0 -0.0005 11 0 0 0 1.05E+09 8.53E+08 - - - 4.6584 0.9798 221125_WJC_METTL3_EV_vs_WT_F06.06230.06230.2 0.376 14-Jul R.RLEPAIQK.F "sp|P56962|STX17_HUMAN,tr|E9PJV6|E9PJV6_HUMAN,tr|E9PIC2|E9PIC2_HUMAN,tr|E9PJW1|E9PJW1_HUMAN,tr|E9PQU9|E9PQU9_HUMAN" 5 953.5658 1.06 77014 6230 2 953.565297 477.7902 Syntaxin-17 OS=Homo sapiens OX=9606 GN=STX17 PE=1 SV=2 8.75 1594.6 - 618436 - - - -0.5432 - 1.433 0.043 - 184.6 4 2 0 -0.0005 8 0 0 0 3.11E+07 2.94E+07 - - - 0.1745 0.9994 221125_WJC_METTL3_EV_vs_WT_F06.06233.06233.2 0.0635 18-Sep K.ASGTLPSQPK.V "sp|Q9NRA8|4ET_HUMAN,tr|B1AKL4|B1AKL4_HUMAN,tr|B0QYZ7|B0QYZ7_HUMAN" 3 984.524 1.22 77015 6233 2 984.523554 493.2693 Eukaryotic translation initiation factor 4E transporter OS=Homo sapiens OX=9606 GN=EIF4ENIF1 PE=1 SV=2 8.8 1594.9 - 1.96E+06 - - - -0.4632 - 1.73 0.32 - 261.5 1 2 0 -0.0005 10 0 0 0 8.27E+08 6.80E+08 - - - 2.9344 0.9998 221125_WJC_METTL3_EV_vs_WT_F06.06235.06235.2 0.00121 16-Aug R.LSYNTASNK.T sp|P49207|RL34_HUMAN 1 996.4876 0.79 77017 6235 2 996.488822 499.2511 60S ribosomal protein L34 OS=Homo sapiens OX=9606 GN=RPL34 PE=1 SV=3 8.59 1595.1 - 5.68E+06 - - - 1.2022 - 1.848 0.479 - 182.4 1 2 0 0.0012 9 0 0 0 2.59E+08 3.29E+08 - - - 4.3552 0.9935 221125_WJC_METTL3_EV_vs_WT_F06.06238.06238.2 0.212 16-Nov K.LDELRDEGK.A "sp|P02768|ALBU_HUMAN,tr|B7WNR0|B7WNR0_HUMAN,tr|H0YA55|H0YA55_HUMAN,tr|A0A0C4DGB6|A0A0C4DGB6_HUMAN,tr|D6RHD5|D6RHD5_HUMAN" 5 1073.5353 999 77019 6238 2 1073.533341 537.7749 Albumin OS=Homo sapiens OX=9606 GN=ALB PE=1 SV=2 4.32 1595.5 - 3.44E+06 - - - -1.8276 - 2.227 0.298 - 408.4 1 2 1 -0.002 9 0 0 0 1.96E+08 0.00E+00 - - - 3.5578 0.995 221125_WJC_METTL3_EV_vs_WT_F06.06240.06240.3 0.0102 13/44 R.GAFGKPQGTVAR.V "sp|P27635|RL10_HUMAN,sp|Q96L21|RL10L_HUMAN,tr|H7C123|H7C123_HUMAN,tr|H7C2C5|H7C2C5_HUMAN,tr|F8W7C6|F8W7C6_HUMAN,tr|X1WI28|X1WI28_HUMAN" 6 1187.6411 0.97 77020 6240 3 1187.644234 396.8876 60S ribosomal protein L10 OS=Homo sapiens OX=9606 GN=RPL10 PE=1 SV=4 11 1595.7 - 592561 - - - 2.6346 - 2.204 0.198 - 211.5 1 2 0 0.0031 12 0 0 0 9.76E+08 1.00E+09 - - - 2.9372 0.9998 221125_WJC_METTL3_EV_vs_WT_F06.06242.06242.2 0.00638 16-Nov R.K[136.11]LLEGEEER[166.11].L "sp|P02545|LMNA_HUMAN,sp|P20700|LMNB1_HUMAN,sp|Q03252|LMNB2_HUMAN,tr|A0A804HL68|A0A804HL68_HUMAN,tr|Q5TCI8|Q5TCI8_HUMAN,tr|A0A6Q8PFJ0|A0A6Q8PFJ0_HUMAN,tr|A0A6Q8PHQ9|A0A6Q8PHQ9_HUMAN,tr|E9PBF6|E9PBF6_HUMAN,tr|Q3BDU5|Q3BDU5_HUMAN" 9 1119.5891 1.48 77021 6242 2 1119.587462 560.8018 Prelamin-A\C OS=Homo sapiens OX=9606 GN=LMNA PE=1 SV=1 4.49 1595.9 - 585911 - - - -1.4389 - 2.139 0.464 - 457 1 2 0 -0.0016 9 0 0 0 4.99E+07 3.38E+07 - - - 4.6673 0.819 221125_WJC_METTL3_EV_vs_WT_F06.06244.06244.2 2.58 18-Aug K.K[136.11]FVC[160.03]PGINVK.C "sp|Q9Y692|GMEB1_HUMAN,sp|Q9UKD1|GMEB2_HUMAN,tr|Q5JTV1|Q5JTV1_HUMAN" 3 1168.6518 - 77023 6244 2 1168.656297 585.3332 Glucocorticoid modulatory element-binding protein 1 OS=Homo sapiens OX=9606 GN=GMEB1 PE=1 SV=2 9.31 1596.2 - 823453 - - - 3.848 - 1.349 0.036 - 141.6 2 2 0 0.0045 10 0 0 0 - - - - - 0.0066 0.9953 221125_WJC_METTL3_EV_vs_WT_F06.06255.06255.3 0.0479 Dec-36 K.EVPVVHTETK.T "sp|Q9Y2J2|E41L3_HUMAN,tr|J3QS83|J3QS83_HUMAN,tr|A0A0A0MRA8|A0A0A0MRA8_HUMAN,tr|A8K968|A8K968_HUMAN,tr|A0A0J9YY18|A0A0J9YY18_HUMAN,tr|A0A0A0MSA4|A0A0A0MSA4_HUMAN" 6 1137.603 0.54 77030 6255 3 1137.599078 380.2083 Band 4.1-like protein 3 OS=Homo sapiens OX=9606 GN=EPB41L3 PE=1 SV=2 5.4 1597.5 - 206399 - - - -3.4379 - 1.808 0.278 - 224.2 1 2 0 -0.0039 10 0 0 0 1.88E+07 3.50E+07 - - - 3.3679 0.9999 221125_WJC_METTL3_EV_vs_WT_F06.06257.06257.2 2.32E-06 24-Dec K.VAPAQPSEEGPGR.K "sp|P23588|IF4B_HUMAN,tr|E7EX17|E7EX17_HUMAN" 2 1293.6313 3.1 77031 6257 2 1293.630747 647.8229 Eukaryotic translation initiation factor 4B OS=Homo sapiens OX=9606 GN=EIF4B PE=1 SV=2 4.53 1597.7 - 6.81E+06 - - - -0.4499 - 1.998 0.606 - 267.8 1 2 0 -0.0006 13 0 0 0 6.55E+08 2.11E+08 - - - 5.2931 0.9999 221125_WJC_METTL3_EV_vs_WT_F06.06259.06259.2 8.13E-05 14-Oct K.HMSVSSIK[136.11].Q "sp|P15927|RFA2_HUMAN,tr|Q5TEJ0|Q5TEJ0_HUMAN" 2 895.4677 1.06 77032 6259 2 895.467362 448.7411 Replication protein A 32 kDa subunit OS=Homo sapiens OX=9606 GN=RPA2 PE=1 SV=1 8.76 1597.9 - 9.07E+06 - - - -0.3641 - 2.019 0.526 - 310.8 1 2 0 -0.0003 8 0 0 0 6.25E+08 5.87E+08 - - - 5.045 0.9965 221125_WJC_METTL3_EV_vs_WT_F06.06260.06260.2 1.12 20-Aug R.GPPPSYGGSSR[166.11].Y "sp|Q96E39|RMXL1_HUMAN,sp|P38159|RBMX_HUMAN,tr|H3BUY5|H3BUY5_HUMAN" 3 1070.502 1.19 77033 6260 2 1070.499969 536.2583 "RNA binding motif protein, X-linked-like-1 OS=Homo sapiens OX=9606 GN=RBMXL1 PE=1 SV=1" 8.75 1598 - 1.70E+06 - - - -1.9365 - 1.405 0.266 - 192.8 1 2 0 -0.0021 11 0 0 0 1.65E+08 1.39E+08 - - - 1.9249 1 221125_WJC_METTL3_EV_vs_WT_F06.06263.06263.3 3.05E-05 Nov-40 R.GHLENNPALEK.L "sp|Q8NHW5|RLA0L_HUMAN,sp|P05388|RLA0_HUMAN,tr|G3V210|G3V210_HUMAN,tr|F8VU65|F8VU65_HUMAN,tr|F8VWV4|F8VWV4_HUMAN,tr|F8VWS0|F8VWS0_HUMAN,tr|F8VS58|F8VS58_HUMAN,tr|F8VW21|F8VW21_HUMAN,tr|F8VZS0|F8VZS0_HUMAN,tr|F8VRK7|F8VRK7_HUMAN,tr|F8VQY6|F8VQY6_HUMAN,tr|F8VPE8|F8VPE8_HUMAN" 12 1220.6149 1.24 77034 6263 3 1220.614997 407.8789 60S acidic ribosomal protein P0-like OS=Homo sapiens OX=9606 GN=RPLP0P6 PE=5 SV=1 5.4 1598.4 - 1.78E+07 - - - 0.0385 - 2.531 0.438 - 312.3 1 2 0 0 11 0 0 0 2.11E+09 1.70E+09 - - - 6.0613 0.9998 221125_WJC_METTL3_EV_vs_WT_F06.06264.06264.2 6.38E-05 18-Aug K.SC[160.03]EQAC[160.03]ESLK.R "sp|P42694|HELZ_HUMAN,tr|J3KT20|J3KT20_HUMAN,tr|J3QS41|J3QS41_HUMAN,tr|A0A075B6R3|A0A075B6R3_HUMAN,tr|J3KS59|J3KS59_HUMAN" 5 1210.4958 2.43 77035 6264 2 1210.495577 606.2552 Probable helicase with zinc finger domain OS=Homo sapiens OX=9606 GN=HELZ PE=1 SV=2 4.53 1598.5 - 1.45E+06 - - - -0.2032 - 1.841 0.476 - 201.6 1 2 0 -0.0002 10 0 0 0 4.78E+07 1.97E+07 - - - 4.2602 0.9983 221125_WJC_METTL3_EV_vs_WT_F06.06265.06265.3 0.0358 Dec-44 R.GAFGK[136.11]PQGTVAR[166.11].V "sp|P27635|RL10_HUMAN,sp|Q96L21|RL10L_HUMAN,tr|H7C123|H7C123_HUMAN,tr|H7C2C5|H7C2C5_HUMAN,tr|F8W7C6|F8W7C6_HUMAN,tr|X1WI28|X1WI28_HUMAN" 6 1205.6636 0.97 77036 6265 3 1205.66276 402.8951 60S ribosomal protein L10 OS=Homo sapiens OX=9606 GN=RPL10 PE=1 SV=4 11 1598.6 - 1.82E+06 - - - -0.676 - 1.844 0.242 - 186.9 1 2 0 -0.0008 12 0 0 0 9.76E+08 1.00E+09 - - - 2.934 0.9998 221125_WJC_METTL3_EV_vs_WT_F06.06270.06270.2 0.00113 16-Oct K.RGEAPFAQR.L "sp|Q9Y2R0|COA3_HUMAN,tr|K7EPV0|K7EPV0_HUMAN" 2 1030.5308 1.43 77039 6270 2 1030.530332 516.2727 "Cytochrome c oxidase assembly factor 3 homolog, mitochondrial OS=Homo sapiens OX=9606 GN=COA3 PE=1 SV=1" 9.6 1599.2 - 4.03E+06 - - - -0.4803 - 2.29 0.352 - 179.2 1 2 0 -0.0005 9 0 0 0 4.86E+08 3.39E+08 - - - 4.0378 0.9986 221125_WJC_METTL3_EV_vs_WT_F06.06272.06272.2 0.0604 16-Aug K.R[166.11]GEAPFAQR[166.11].L "sp|Q9Y2R0|COA3_HUMAN,tr|K7EPV0|K7EPV0_HUMAN" 2 1050.5474 1.43 77041 6272 2 1050.544347 526.281 "Cytochrome c oxidase assembly factor 3 homolog, mitochondrial OS=Homo sapiens OX=9606 GN=COA3 PE=1 SV=1" 9.6 1599.4 - 3.44E+06 - - - -2.8747 - 2.061 0.31 - 108.7 1 2 0 -0.003 9 0 0 0 4.86E+08 3.39E+08 - - - 3.4219 0.9999 221125_WJC_METTL3_EV_vs_WT_F06.06279.06279.2 0.0227 20-Sep K.ISTTTSEEPC[160.03]R.D sp|O15119|TBX3_HUMAN 1 1279.5714 0.78 77045 6279 2 1279.571825 640.793 T-box transcription factor TBX3 OS=Homo sapiens OX=9606 GN=TBX3 PE=1 SV=4 4.53 1600.3 - 1.64E+06 - - - 0.3079 - 2.224 0.48 - 425.3 1 2 0 0.0004 11 0 0 0 1.42E+08 1.82E+08 - - - 4.7485 0.9995 221125_WJC_METTL3_EV_vs_WT_F06.06284.06284.2 0.000516 16-Sep K.C[160.03]PEPC[160.03]PPPK.C "sp|P22531|SPR2E_HUMAN,sp|P35326|SPR2A_HUMAN,sp|Q96RM1|SPR2F_HUMAN,sp|P22532|SPR2D_HUMAN,sp|P35325|SPR2B_HUMAN,sp|Q9BYE4|SPR2G_HUMAN" 6 1080.4732 5.59 77048 6284 2 1080.471052 541.2439 Small proline-rich protein 2E OS=Homo sapiens OX=9606 GN=SPRR2E PE=2 SV=2 5.99 1600.9 - 403840 - - - -2.0223 - 1.613 0.469 - 293.9 1 2 0 -0.0022 9 0 0 0 2.50E+07 4.47E+06 - - - 3.8875 0.9991 221125_WJC_METTL3_EV_vs_WT_F06.06285.06285.2 0.0159 14-Aug R.C[160.03]EYSVGNK.H "sp|Q6W2J9|BCOR_HUMAN,tr|H7BZ37|H7BZ37_HUMAN,tr|H7C2V9|H7C2V9_HUMAN,tr|H7BYY2|H7BYY2_HUMAN,tr|H7C231|H7C231_HUMAN" 5 955.4069 1.52 77049 6285 2 955.406223 478.7107 BCL-6 corepressor OS=Homo sapiens OX=9606 GN=BCOR PE=1 SV=1 5.99 1601 - 608167 - - - -0.7421 - 1.324 0.354 - 200.2 1 2 0 -0.0007 8 0 0 0 8.59E+07 5.64E+07 - - - 2.5019 0.9996 221125_WJC_METTL3_EV_vs_WT_F06.06289.06289.2 0.034 18-Sep K.ASGTLPSQPK[136.11].V "sp|Q9NRA8|4ET_HUMAN,tr|B1AKL4|B1AKL4_HUMAN,tr|B0QYZ7|B0QYZ7_HUMAN" 3 992.5382 1.22 77051 6289 2 992.537298 497.2764 Eukaryotic translation initiation factor 4E transporter OS=Homo sapiens OX=9606 GN=EIF4ENIF1 PE=1 SV=2 8.8 1601.4 - 7.53E+06 - - - -0.9189 - 1.803 0.355 - 258.9 1 2 0 -0.0009 10 0 0 0 8.28E+08 6.81E+08 - - - 3.3081 0.9984 221125_WJC_METTL3_EV_vs_WT_F06.06290.06290.3 0.00308 Sep-36 K.AQQNHALLER.E "sp|Q9NVU0|RPC5_HUMAN,tr|A0A0C4DH01|A0A0C4DH01_HUMAN" 2 1178.6156 5.31 77052 6290 3 1178.61506 393.8791 DNA-directed RNA polymerase III subunit RPC5 OS=Homo sapiens OX=9606 GN=POLR3E PE=1 SV=1 6.79 1601.6 - 451217 - - - -0.4743 - 1.903 0.231 - 137.4 1 2 0 -0.0006 10 0 0 0 1.81E+07 3.41E+06 - - - 2.9944 0.9995 221125_WJC_METTL3_EV_vs_WT_F06.06291.06291.2 8.18E-05 18-Oct K.DGVQVTESGK.F "sp|Q92626|PXDN_HUMAN,tr|H7C1W1|H7C1W1_HUMAN" 2 1018.4931 1.05 77053 6291 2 1018.493768 510.2538 Peroxidasin homolog OS=Homo sapiens OX=9606 GN=PXDN PE=1 SV=2 4.37 1601.7 - 413480 - - - 0.6519 - 1.949 0.32 - 350.7 1 2 0 0.0007 10 0 0 0 1.66E+07 1.58E+07 - - - 3.267 0.9349 221125_WJC_METTL3_EV_vs_WT_F06.06292.06292.3 0.0171 Nov-36 F.ALSTHPYGC[160.03]R.V "sp|Q14671|PUM1_HUMAN,tr|Q5T1Z8|Q5T1Z8_HUMAN,tr|H0YDK8|H0YDK8_HUMAN,tr|H0YEH2|H0YEH2_HUMAN,tr|Q5T1Z4|Q5T1Z4_HUMAN,tr|H0YDC5|H0YDC5_HUMAN,tr|E9PR38|E9PR38_HUMAN,tr|H0YDQ6|H0YDQ6_HUMAN" 8 1160.5397 0.96 77054 6292 3 1160.539851 387.8538 Pumilio homolog 1 OS=Homo sapiens OX=9606 GN=PUM1 PE=1 SV=3 8.27 1601.8 - 366584 - - - 0.1499 - 2.018 0.271 - 164.1 1 1 0 0.0002 10 0 0 0 1.47E+07 1.53E+07 - - - 3.6118 0.9929 221125_WJC_METTL3_EV_vs_WT_F06.06293.06293.2 0.0211 22-Aug R.GAFGKPQGTVAR.V "sp|P27635|RL10_HUMAN,sp|Q96L21|RL10L_HUMAN,tr|H7C123|H7C123_HUMAN,tr|H7C2C5|H7C2C5_HUMAN,tr|F8W7C6|F8W7C6_HUMAN,tr|X1WI28|X1WI28_HUMAN" 6 1187.6411 1 77055 6293 2 1187.638534 594.8278 60S ribosomal protein L10 OS=Homo sapiens OX=9606 GN=RPL10 PE=1 SV=4 11 1601.9 - 341480 - - - -2.1648 - 1.294 0.24 - 137.1 1 2 0 -0.0026 12 0 0 0 1.34E+08 1.35E+08 - - - 1.491 0.9997 221125_WJC_METTL3_EV_vs_WT_F06.06297.06297.2 0.00144 14-Jul R.C[160.03]EYSVGNK[136.11].H "sp|Q6W2J9|BCOR_HUMAN,tr|H7BZ37|H7BZ37_HUMAN,tr|H7C2V9|H7C2V9_HUMAN,tr|H7BYY2|H7BYY2_HUMAN,tr|H7C231|H7C231_HUMAN" 5 963.4211 1.52 77058 6297 2 963.420884 482.7178 BCL-6 corepressor OS=Homo sapiens OX=9606 GN=BCOR PE=1 SV=1 5.99 1602.3 - 1.14E+06 - - - -0.2574 - 1.414 0.453 - 212.1 1 2 0 -0.0002 8 0 0 0 8.59E+07 5.64E+07 - - - 3.4316 0.9939 221125_WJC_METTL3_EV_vs_WT_F06.06298.06298.2 2.26 14-Sep R.R[166.11]QQEEILR[166.11].R "sp|Q6Y7W6|GGYF2_HUMAN,tr|A0A7I2V3H7|A0A7I2V3H7_HUMAN,tr|I1E4Y6|I1E4Y6_HUMAN,tr|A0A7I2V516|A0A7I2V516_HUMAN,tr|A0A7I2V3H0|A0A7I2V3H0_HUMAN,tr|C9JHW1|C9JHW1_HUMAN,tr|A0A7I2V361|A0A7I2V361_HUMAN,tr|E7ESB6|E7ESB6_HUMAN" 8 1090.5998 2.9 77059 6298 2 1090.597917 546.3072 GRB10-interacting GYF protein 2 OS=Homo sapiens OX=9606 GN=GIGYF2 PE=1 SV=1 6.14 1602.4 - 623310 - - - -1.7229 - 1.614 0.121 - 187.5 1 2 0 -0.0019 8 0 0 0 7.34E+07 2.53E+07 - - - 1.3779 0.9998 221125_WJC_METTL3_EV_vs_WT_F06.06303.06303.2 0.00143 24-Dec K.VAPAQPSEEGPGR[166.11].K "sp|P23588|IF4B_HUMAN,tr|E7EX17|E7EX17_HUMAN" 2 1303.6396 3.1 77063 6303 2 1303.641158 652.8271 Eukaryotic translation initiation factor 4B OS=Homo sapiens OX=9606 GN=EIF4B PE=1 SV=2 4.53 1602.9 - 973968 - - - 1.1959 - 2.065 0.461 - 276.1 1 2 0 0.0016 13 0 0 0 6.31E+08 2.04E+08 - - - 4.3065 0.9992 221125_WJC_METTL3_EV_vs_WT_F06.06307.06307.2 0.00614 20-Jul R.GPPPSYGGSSR.Y "sp|Q96E39|RMXL1_HUMAN,sp|P38159|RBMX_HUMAN,tr|H3BUY5|H3BUY5_HUMAN" 3 1060.4938 1.13 77065 6307 2 1060.493582 531.2542 "RNA binding motif protein, X-linked-like-1 OS=Homo sapiens OX=9606 GN=RBMXL1 PE=1 SV=1" 8.75 1603.4 - 1.62E+06 - - - -0.1792 - 1.352 0.361 - 89.3 1 2 0 -0.0002 11 0 0 0 1.40E+08 1.24E+08 - - - 2.5231 0.9936 221125_WJC_METTL3_EV_vs_WT_F06.06312.06312.2 0.641 14-Nov R.RQQEEILR.R "sp|Q6Y7W6|GGYF2_HUMAN,tr|A0A7I2V3H7|A0A7I2V3H7_HUMAN,tr|I1E4Y6|I1E4Y6_HUMAN,tr|A0A7I2V516|A0A7I2V516_HUMAN,tr|A0A7I2V3H0|A0A7I2V3H0_HUMAN,tr|C9JHW1|C9JHW1_HUMAN,tr|A0A7I2V361|A0A7I2V361_HUMAN,tr|E7ESB6|E7ESB6_HUMAN" 8 1070.5833 2.9 77068 6312 2 1070.581538 536.2989 GRB10-interacting GYF protein 2 OS=Homo sapiens OX=9606 GN=GIGYF2 PE=1 SV=1 6.14 1604 - 2.10E+06 - - - -1.6047 - 1.541 0.128 - 267.8 1 2 0 -0.0017 8 0 0 0 7.34E+07 2.53E+07 - - - 1.2901 0.8773 221125_WJC_METTL3_EV_vs_WT_F06.06317.06317.2 0.0564 20-Jul F.ETEADAQQAYK.Y sp|Q92615|LAR4B_HUMAN 1 1252.5572 1.54 77073 6317 2 1252.556336 627.2859 La-related protein 4B OS=Homo sapiens OX=9606 GN=LARP4B PE=1 SV=3 4.14 1604.6 - 92998.6 - - - -0.6587 - 1.347 0.254 - 66.1 1 1 0 -0.0008 11 0 0 0 4.63E+06 3.02E+06 - - - 1.7226 0.7856 221125_WJC_METTL3_EV_vs_WT_F06.06322.06322.2 0.519 14-Sep F.SITYKPVK.H "sp|P62841|RS15_HUMAN,tr|K7EM56|K7EM56_HUMAN,tr|A0A0B4J2B4|A0A0B4J2B4_HUMAN,tr|K7ELC2|K7ELC2_HUMAN,tr|K7EQJ5|K7EQJ5_HUMAN,tr|S4R417|S4R417_HUMAN" 6 934.5488 1.29 77077 6322 2 934.548923 468.2817 40S ribosomal protein S15 OS=Homo sapiens OX=9606 GN=RPS15 PE=1 SV=2 9.7 1605.1 - 977183 - - - 0.1659 - 1.346 0.169 - 240.4 1 1 0 0.0002 8 0 0 0 3.66E+07 2.84E+07 - - - 1.1853 0.9994 221125_WJC_METTL3_EV_vs_WT_F06.06323.06323.2 0.000255 22-Aug R.GAFGK[136.11]PQGTVAR[166.11].V "sp|P27635|RL10_HUMAN,sp|Q96L21|RL10L_HUMAN,tr|H7C123|H7C123_HUMAN,tr|H7C2C5|H7C2C5_HUMAN,tr|F8W7C6|F8W7C6_HUMAN,tr|X1WI28|X1WI28_HUMAN" 6 1205.6636 1 77078 6323 2 1205.662843 603.8391 60S ribosomal protein L10 OS=Homo sapiens OX=9606 GN=RPL10 PE=1 SV=4 11 1605.2 - 839328 - - - -0.6071 - 1.743 0.314 - 122.8 1 2 0 -0.0007 12 0 0 0 1.34E+08 1.35E+08 - - - 2.8219 0.9996 221125_WJC_METTL3_EV_vs_WT_F06.06337.06337.2 0.0786 24-Nov K.LANSEPVGTQTAK.L "sp|Q9UPN3|MACF1_HUMAN,tr|A0A804HL78|A0A804HL78_HUMAN,tr|H3BQK9|H3BQK9_HUMAN,tr|A0A7P0MQR8|A0A7P0MQR8_HUMAN,tr|H0Y390|H0Y390_HUMAN,tr|H3BPE1|H3BPE1_HUMAN,tr|A0A590UJG2|A0A590UJG2_HUMAN,tr|A0A0A6YYJ5|A0A0A6YYJ5_HUMAN" 8 1314.6779 1.7 77088 6337 2 1314.676559 658.3462 "Microtubule-actin cross-linking factor 1, isoforms 1\2\3\5 OS=Homo sapiens OX=9606 GN=MACF1 PE=1 SV=4" 6 1607 - 314912 - - - -1.0543 - 2.123 0.337 - 138.9 1 2 0 -0.0014 13 0 0 0 1.94E+07 1.15E+07 - - - 3.4618 0.9226 221125_WJC_METTL3_EV_vs_WT_F06.06339.06339.2 0.852 16-May R.QAEEEDLQR.E sp|Q9H1K0|RBNS5_HUMAN 1 1116.5047 1.26 77090 6339 2 1116.506362 559.2596 Rabenosyn-5 OS=Homo sapiens OX=9606 GN=RBSN PE=1 SV=2 4 1607.2 - 233488 - - - 1.4608 - 1.024 0.084 - 47.8 2 2 0 0.0016 9 0 0 0 2.23E+06 1.77E+06 - - - -0.4049 0.9996 221125_WJC_METTL3_EV_vs_WT_F06.06343.06343.2 0.0333 16-Sep R.KLLEGEEC[160.03]R.M "sp|Q86Y46|K2C73_HUMAN,sp|Q7RTS7|K2C74_HUMAN,sp|P48668|K2C6C_HUMAN,sp|Q01546|K22O_HUMAN,sp|P12036|NFH_HUMAN,sp|P04259|K2C6B_HUMAN,sp|P13647|K2C5_HUMAN,sp|P35908|K22E_HUMAN,sp|O95678|K2C75_HUMAN,sp|P02538|K2C6A_HUMAN,tr|H0YI76|H0YI76_HUMAN,tr|H0YIC5|H0YIC5_HUMAN,tr|F8W1S1|F8W1S1_HUMAN" 13 1132.5547 7822.4 77092 6343 2 1132.555086 567.2846 "Keratin, type II cytoskeletal 73 OS=Homo sapiens OX=9606 GN=KRT73 PE=1 SV=1" 4.79 1607.8 - 2.04E+06 - - - 0.3779 - 1.995 0.314 - 308.9 1 2 0 0.0004 9 0 0 0 3.20E+09 4.09E+05 - - - 3.3581 0.9877 221125_WJC_METTL3_EV_vs_WT_F06.06345.06345.2 0.189 14-Jun K.QAFEQIK[136.11]K[136.11].E "sp|Q14683|SMC1A_HUMAN,tr|G8JLG1|G8JLG1_HUMAN,tr|A0A6Q8PHC3|A0A6Q8PHC3_HUMAN,tr|V9GY57|V9GY57_HUMAN" 4 1006.5782 1.11 77094 6345 2 1006.579338 504.2964 Structural maintenance of chromosomes protein 1A OS=Homo sapiens OX=9606 GN=SMC1A PE=1 SV=2 8.59 1607.9 - 1.21E+06 - - - 1.0998 - 1.158 0.165 - 106.9 1 2 0 0.0011 8 0 0 0 3.43E+07 3.10E+07 - - - 0.7018 0.9997 221125_WJC_METTL3_EV_vs_WT_F06.06354.06354.3 0.00112 Oct-36 K.ADAEYYAAHK.Y "sp|O75477|ERLN1_HUMAN,tr|B0QZ43|B0QZ43_HUMAN" 2 1137.5091 0.69 77101 6354 3 1137.510488 380.177 Erlin-1 OS=Homo sapiens OX=9606 GN=ERLIN1 PE=1 SV=2 5.32 1609.1 - 507749 - - - 1.2308 - 1.879 0.373 - 142.5 1 2 0 0.0014 10 0 0 0 1.30E+07 1.88E+07 - - - 4.5402 0.9998 221125_WJC_METTL3_EV_vs_WT_F06.06357.06357.2 1.69E-05 18-Sep R.YDSQVAEENR.F sp|O60942|MCE1_HUMAN 1 1209.5262 1.24 77104 6357 2 1209.527417 605.7704 mRNA-capping enzyme OS=Homo sapiens OX=9606 GN=RNGTT PE=1 SV=1 4.14 1609.3 - 492683 - - - 1.0103 - 1.98 0.541 - 285.3 1 2 0 0.0012 10 0 0 0 8.61E+06 6.93E+06 - - - 4.9432 0.9618 221125_WJC_METTL3_EV_vs_WT_F06.06364.06364.2 4.55E-05 20-Sep K.LQETQMSTTSK.L "sp|Q13948|CASP_HUMAN,sp|P39880|CUX1_HUMAN,tr|A0A2R8Y8D0|A0A2R8Y8D0_HUMAN,tr|A0A2R8Y852|A0A2R8Y852_HUMAN,tr|A0A2R8YDI1|A0A2R8YDI1_HUMAN" 5 1252.5969 1.56 77109 6364 2 1252.60575 627.3057 Protein CASP OS=Homo sapiens OX=9606 GN=CUX1 PE=1 SV=2 6 1610.2 - 620030 - - - 7.0517 - 1.778 0.315 - 219.9 1 2 0 0.0088 11 0 0 0 4.64E+07 2.98E+07 - - - 2.9217 0.9988 221125_WJC_METTL3_EV_vs_WT_F06.06365.06365.2 0.000328 16-Sep R.ASYDDPYKK.A sp|Q96PK6|RBM14_HUMAN 1 1085.5029 1.44 77110 6365 2 1085.498913 543.7587 RNA-binding protein 14 OS=Homo sapiens OX=9606 GN=RBM14 PE=1 SV=2 6 1610.4 - 551311 - - - -3.7098 - 1.589 0.551 - 276.9 1 2 0 -0.004 9 0 0 0 1.86E+07 1.30E+07 - - - 4.4492 0.9787 221125_WJC_METTL3_EV_vs_WT_F06.06368.06368.2 0.672 14-Aug A.SYDDPYKK.A sp|Q96PK6|RBM14_HUMAN 1 1014.4658 6 77113 6368 2 1014.465657 508.2402 RNA-binding protein 14 OS=Homo sapiens OX=9606 GN=RBM14 PE=1 SV=2 5.68 1610.8 - 408048 - - - -0.1666 - 1.614 0.389 - 203.5 1 1 0 -0.0002 8 0 0 0 1.24E+07 2.06E+06 - - - 3.3579 0.9996 221125_WJC_METTL3_EV_vs_WT_F06.06374.06374.2 0.000429 20-Oct R.QTTQDAPEEVR[166.11].N sp|Q9P013|CWC15_HUMAN 1 1282.6029 0.98 77117 6374 2 1282.604617 642.3087 Spliceosome-associated protein CWC15 homolog OS=Homo sapiens OX=9606 GN=CWC15 PE=1 SV=2 4.14 1611.6 - 174996 - - - 1.3551 - 1.647 0.449 - 223.5 1 2 0 0.0017 11 0 0 0 3.46E+07 3.53E+07 - - - 3.7066 0.9831 221125_WJC_METTL3_EV_vs_WT_F06.06387.06387.2 0.112 18-Jun K.ETEGDVTSVK.D sp|P50990|TCPQ_HUMAN 1 1063.5033 0.39 77126 6387 2 1063.506805 532.7589 T-complex protein 1 subunit theta OS=Homo sapiens OX=9606 GN=CCT8 PE=1 SV=4 4.14 1613.1 - 1.08E+06 - - - 3.2637 - 1.149 0.275 - 82.8 1 2 0 0.0035 10 0 0 0 4.81E+08 1.22E+09 - - - 1.4587 0.9996 221125_WJC_METTL3_EV_vs_WT_F06.06388.06388.2 2.23E-05 18-Oct R.TTPLNQESDR[166.11].F "sp|Q9UIA9|XPO7_HUMAN,tr|E7ESC6|E7ESC6_HUMAN" 2 1169.5552 0.49 77127 6388 2 1169.557088 585.7849 Exportin-7 OS=Homo sapiens OX=9606 GN=XPO7 PE=1 SV=3 4.37 1613.2 - 431757 - - - 1.6143 - 1.712 0.469 - 481.6 1 2 0 0.0019 10 0 0 0 3.64E+07 7.40E+07 - - - 4.0052 0.9998 221125_WJC_METTL3_EV_vs_WT_F06.06389.06389.2 0.000259 28-Sep R.LADSGDGAGPSPEEK.D sp|Q92917|GPKOW_HUMAN 1 1428.6369 1.79 77128 6389 2 1428.63802 715.3257 G-patch domain and KOW motifs-containing protein OS=Homo sapiens OX=9606 GN=GPKOW PE=1 SV=2 3.92 1613.3 - 117771 - - - 0.8064 - 1.969 0.487 - 206.1 1 2 0 0.0012 15 0 0 0 7.79E+06 4.35E+06 - - - 4.3033 0.9998 221125_WJC_METTL3_EV_vs_WT_F06.06391.06391.2 2.35E-05 14-Oct K.HMSVSSIK.Q "sp|P15927|RFA2_HUMAN,tr|Q5TEJ0|Q5TEJ0_HUMAN" 2 887.4535 1.06 77129 6391 2 887.45342 444.734 Replication protein A 32 kDa subunit OS=Homo sapiens OX=9606 GN=RPA2 PE=1 SV=1 8.76 1613.6 - 3.92E+06 - - - -0.0766 - 1.904 0.384 - 328.1 1 2 0 -0.0001 8 0 0 0 6.27E+08 5.93E+08 - - - 3.8193 0.9922 221125_WJC_METTL3_EV_vs_WT_F06.06393.06393.3 0.0801 Aug-40 R.IYGESADAVK[136.11]K[136.11].A "sp|P51114|FXR1_HUMAN,tr|E7EU85|E7EU85_HUMAN,tr|E9PFF5|E9PFF5_HUMAN,tr|B4DXZ6|B4DXZ6_HUMAN" 4 1195.642 1.42 77130 6393 3 1195.641883 399.5546 Fragile X mental retardation syndrome-related protein 1 OS=Homo sapiens OX=9606 GN=FXR1 PE=1 SV=3 6.07 1613.8 - 1.58E+06 - - - -0.0585 - 1.5 0.203 - 57.9 1 2 0 -0.0001 11 0 0 0 3.54E+08 2.50E+08 - - - 1.9551 0.9884 221125_WJC_METTL3_EV_vs_WT_F06.06394.06394.2 0.0984 14-Aug R.NKLEGEIR.R "sp|Q4VCS5|AMOT_HUMAN,sp|Q8IY63|AMOL1_HUMAN,tr|A6NP16|A6NP16_HUMAN,tr|E7ERM3|E7ERM3_HUMAN" 4 957.5243 1.86 77131 6394 2 957.523978 479.7694 Angiomotin OS=Homo sapiens OX=9606 GN=AMOT PE=1 SV=1 6.14 1613.8 - 1.47E+06 - - - -0.3822 - 1.647 0.243 - 336.1 1 2 1 -0.0004 8 0 0 0 4.30E+07 2.31E+07 - - - 2.3405 0.9658 221125_WJC_METTL3_EV_vs_WT_F06.06395.06395.2 0.358 14-Jul R.SINNYNPK.D sp|Q9Y5A9|YTHD2_HUMAN 1 948.4665 0.77 77132 6395 2 948.465404 475.2405 YTH domain-containing family protein 2 OS=Homo sapiens OX=9606 GN=YTHDF2 PE=1 SV=2 8.31 1614 - 724799 - - - -1.1503 - 1.008 0.122 - 134 1 2 0 -0.0011 8 0 0 0 1.31E+08 1.71E+08 - - - -0.0342 0.9988 221125_WJC_METTL3_EV_vs_WT_F06.06400.06400.2 0.00202 20-Jul R.IYGESADAVK[136.11]K[136.11].A "sp|P51114|FXR1_HUMAN,tr|E7EU85|E7EU85_HUMAN,tr|E9PFF5|E9PFF5_HUMAN,tr|B4DXZ6|B4DXZ6_HUMAN" 4 1195.642 1.38 77135 6400 2 1195.639315 598.8283 Fragile X mental retardation syndrome-related protein 1 OS=Homo sapiens OX=9606 GN=FXR1 PE=1 SV=3 6.07 1614.6 - 398118 - - - -2.2063 - 1.336 0.438 - 114.3 1 2 0 -0.0026 11 0 0 0 5.53E+07 4.00E+07 - - - 3.0589 0.9997 221125_WJC_METTL3_EV_vs_WT_F06.06402.06402.2 3.15E-07 20-Dec R.QTTQDAPEEVR.N sp|Q9P013|CWC15_HUMAN 1 1272.5946 0.98 77137 6402 2 1272.597597 637.3046 Spliceosome-associated protein CWC15 homolog OS=Homo sapiens OX=9606 GN=CWC15 PE=1 SV=2 4.14 1614.9 - 426134 - - - 2.348 - 2.514 0.497 - 689 1 2 0 0.003 11 0 0 0 3.46E+07 3.53E+07 - - - 5.2048 0.9981 221125_WJC_METTL3_EV_vs_WT_F06.06404.06404.2 0.00231 28-Aug R.LADSGDGAGPSPEEK[136.11].D sp|Q92917|GPKOW_HUMAN 1 1436.6511 1.79 77139 6404 2 1436.646184 719.3328 G-patch domain and KOW motifs-containing protein OS=Homo sapiens OX=9606 GN=GPKOW PE=1 SV=2 3.92 1615.2 - 105595 - - - -3.3996 - 1.874 0.393 - 167.9 1 2 0 -0.0049 15 0 0 0 7.79E+06 4.35E+06 - - - 3.4863 0.9993 221125_WJC_METTL3_EV_vs_WT_F06.06407.06407.2 0.108 16-Sep R.QFTSSSSMK.G "sp|P02533|K1C14_HUMAN,sp|P08779|K1C16_HUMAN,tr|K7ENV3|K7ENV3_HUMAN" 3 1001.4488 999 77140 6407 2 1001.448336 501.7317 "Keratin, type I cytoskeletal 14 OS=Homo sapiens OX=9606 GN=KRT14 PE=1 SV=4" 8.75 1615.6 - 1.26E+06 - - - -0.4593 - 1.655 0.301 - 251.6 1 2 0 -0.0005 9 0 0 0 1.73E+08 0.00E+00 - - - 2.7216 0.7735 221125_WJC_METTL3_EV_vs_WT_F06.06421.06421.2 0.576 18-Apr G.AAC[160.03]GPHEEC[160.03]R.L "sp|Q9Y6R7|FCGBP_HUMAN,tr|A0A087WXI2|A0A087WXI2_HUMAN" 2 1185.4655 113.78 77149 6421 2 1185.465212 593.74 IgGFc-binding protein OS=Homo sapiens OX=9606 GN=FCGBP PE=1 SV=3 5.4 1617.2 - 4.18E+06 - - - -0.2649 - 0.958 0.298 - 58.8 1 1 0 -0.0003 10 0 0 0 1.26E+08 1.11E+06 - - - 1.1222 0.9948 221125_WJC_METTL3_EV_vs_WT_F06.06424.06424.2 0.0668 16-Jul R.SGHFEQAIK[136.11].E "sp|Q01082|SPTB2_HUMAN,tr|A0A087WUZ3|A0A087WUZ3_HUMAN" 2 1023.5229 1.48 77152 6424 2 1023.522227 512.7687 "Spectrin beta chain, non-erythrocytic 1 OS=Homo sapiens OX=9606 GN=SPTBN1 PE=1 SV=2" 6.47 1617.4 - 476032 - - - -0.6517 - 1.305 0.177 - 111.3 1 2 0 -0.0007 9 0 0 0 2.96E+07 2.00E+07 - - - 1.1183 0.9999 221125_WJC_METTL3_EV_vs_WT_F06.06430.06430.2 0.000197 16-Nov R.SGHFEQAIK.E "sp|Q01082|SPTB2_HUMAN,tr|A0A087WUZ3|A0A087WUZ3_HUMAN" 2 1015.5087 1.4 77156 6430 2 1015.50824 508.7616 "Spectrin beta chain, non-erythrocytic 1 OS=Homo sapiens OX=9606 GN=SPTBN1 PE=1 SV=2" 6.47 1618.2 - 528306 - - - -0.4471 - 2.158 0.473 - 444.6 1 2 0 -0.0005 9 0 0 0 2.87E+07 2.05E+07 - - - 4.7597 0.9999 221125_WJC_METTL3_EV_vs_WT_F06.06431.06431.2 0.000126 20-Nov R.IYGESADAVKK.A "sp|P51114|FXR1_HUMAN,tr|E7EU85|E7EU85_HUMAN,tr|E9PFF5|E9PFF5_HUMAN,tr|B4DXZ6|B4DXZ6_HUMAN" 4 1179.6136 1.38 77157 6431 2 1179.612949 590.8141 Fragile X mental retardation syndrome-related protein 1 OS=Homo sapiens OX=9606 GN=FXR1 PE=1 SV=3 6.07 1618.3 - 1.69E+06 - - - -0.512 - 2.213 0.575 - 330.5 1 2 0 -0.0006 11 0 0 0 5.53E+07 4.00E+07 - - - 5.4367 0.9997 221125_WJC_METTL3_EV_vs_WT_F06.06432.06432.2 0.00153 18-Nov K.QQEQADSLER[166.11].S "sp|Q14980|NUMA1_HUMAN,tr|A0A087WY61|A0A087WY61_HUMAN" 2 1212.561 1.41 77158 6432 2 1212.557982 607.2878 Nuclear mitotic apparatus protein 1 OS=Homo sapiens OX=9606 GN=NUMA1 PE=1 SV=2 4.14 1618.4 - 774423 - - - -2.5005 - 2.155 0.524 - 639.8 1 2 0 -0.003 10 0 0 0 2.23E+07 1.58E+07 - - - 5.0534 0.9816 221125_WJC_METTL3_EV_vs_WT_F06.06433.06433.2 0.00671 16-Sep Y.GESADAVKK.A "sp|P51114|FXR1_HUMAN,tr|E7EU85|E7EU85_HUMAN,tr|E9PFF5|E9PFF5_HUMAN,tr|B4DXZ6|B4DXZ6_HUMAN" 4 903.4662 0.32 77159 6433 2 903.46615 452.7404 Fragile X mental retardation syndrome-related protein 1 OS=Homo sapiens OX=9606 GN=FXR1 PE=1 SV=3 6.07 1618.5 - 627394 - - - -0.0122 - 1.972 0.341 - 334.7 1 1 0 0 9 0 0 0 1.08E+07 3.37E+07 - - - 3.5241 0.9539 221125_WJC_METTL3_EV_vs_WT_F06.06437.06437.2 0.699 16-Jun R.LQGEIAHVK.K sp|P35908|K22E_HUMAN 1 993.5607 38.02 77161 6437 2 993.563694 497.7876 "Keratin, type II cytoskeletal 2 epidermal OS=Homo sapiens OX=9606 GN=KRT2 PE=1 SV=2" 6.75 1619.1 - 3.58E+06 - - - 2.9832 - 1.262 0.165 - 76.4 6 2 0 0.003 9 0 0 0 7.35E+07 1.93E+06 - - - 0.5844 0.9987 221125_WJC_METTL3_EV_vs_WT_F06.06438.06438.2 0.00391 20-Aug K.GQGALDPNGTR.V sp|Q9HC52|CBX8_HUMAN 1 1084.5261 0.66 77162 6438 2 1084.528924 543.2703 Chromobox protein homolog 8 OS=Homo sapiens OX=9606 GN=CBX8 PE=1 SV=3 5.84 1619.1 - 2.86E+06 - - - 2.5716 - 1.726 0.375 - 168.2 1 2 0 0.0028 11 0 0 0 8.32E+07 1.26E+08 - - - 3.2864 0.9986 221125_WJC_METTL3_EV_vs_WT_F06.06439.06439.2 0.0124 14-Sep R.SINNYNPK[136.11].D sp|Q9Y5A9|YTHD2_HUMAN 1 956.4807 1.25 77163 6439 2 956.479049 479.2476 YTH domain-containing family protein 2 OS=Homo sapiens OX=9606 GN=YTHDF2 PE=1 SV=2 8.31 1619.2 - 1.53E+06 - - - -1.7209 - 1.386 0.35 - 199.6 1 2 0 -0.0016 8 0 0 0 1.31E+08 1.04E+08 - - - 2.6101 0.9999 221125_WJC_METTL3_EV_vs_WT_F06.06441.06441.2 1.75E-05 22-Dec K.VAQGVSGAVQDK.G "sp|P12268|IMDH2_HUMAN,tr|A0A7I2YQK5|A0A7I2YQK5_HUMAN,tr|H0Y4R1|H0Y4R1_HUMAN,tr|A0A7I2V2T3|A0A7I2V2T3_HUMAN,tr|E7ETK5|E7ETK5_HUMAN" 5 1157.6041 0.71 77165 6441 2 1157.603573 579.8093 Inosine-5'-monophosphate dehydrogenase 2 OS=Homo sapiens OX=9606 GN=IMPDH2 PE=1 SV=2 5.81 1619.4 - 544280 - - - -0.4129 - 2.31 0.472 - 477.4 1 2 0 -0.0005 12 0 0 0 2.41E+08 3.39E+08 - - - 4.73 0.9771 221125_WJC_METTL3_EV_vs_WT_F06.06446.06446.2 4.74 12-Jun K.K[136.11]QEFLEK[136.11].K "sp|Q9H444|CHM4B_HUMAN,sp|P59074|CHM4P_HUMAN" 2 936.5251 2.54 77168 6446 2 936.525256 469.2698 Charged multivesicular body protein 4b OS=Homo sapiens OX=9606 GN=CHMP4B PE=1 SV=1 6.14 1620.1 - 634548 - - - 0.1313 - 1.202 0.061 - 135.4 1 2 0 0.0001 7 0 0 0 4.52E+07 1.78E+07 - - - 0.0745 0.9999 221125_WJC_METTL3_EV_vs_WT_F06.06448.06448.2 0.000126 28-Dec R.LADSGDGAGPSPEEK[136.11].D sp|Q92917|GPKOW_HUMAN 1 1436.6511 1.79 77170 6448 2 1436.649729 719.3328 G-patch domain and KOW motifs-containing protein OS=Homo sapiens OX=9606 GN=GPKOW PE=1 SV=2 3.92 1620.4 - 145728 - - - -0.932 - 2.5 0.518 - 350.2 1 2 0 -0.0013 15 0 0 0 7.79E+06 4.35E+06 - - - 5.1193 1 221125_WJC_METTL3_EV_vs_WT_F06.06453.06453.3 5.33E-06 Oct-52 K.K[136.11]GPGEVAGTVTGQK[136.11].R "sp|Q86U44|MTA70_HUMAN,tr|F5H6D8|F5H6D8_HUMAN,tr|H0YFV6|H0YFV6_HUMAN,tr|B4DTN4|B4DTN4_HUMAN" 4 1343.738 0 77173 6453 3 1343.735888 448.9199 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 8.59 1621 - 1.62E+06 - - - -1.5561 - 2.34 0.509 - 120.8 1 2 0 -0.0021 14 0 0 0 1.94E+05 7.04E+07 - - - 6.4736 0.9879 221125_WJC_METTL3_EV_vs_WT_F06.06457.06457.2 0.00248 20-Sep K.VTSTNNMAYNK.A "sp|Q96HC4|PDLI5_HUMAN,tr|A0A0D9SFR4|A0A0D9SFR4_HUMAN" 2 1241.571 6.36 77177 6457 2 1241.563656 621.7928 PDZ and LIM domain protein 5 OS=Homo sapiens OX=9606 GN=PDLIM5 PE=1 SV=5 8.56 1621.5 - 328505 - - - -5.9449 - 1.433 0.469 - 142.7 1 2 0 -0.0074 11 0 0 0 4.44E+07 6.97E+06 - - - 3.476 0.9362 221125_WJC_METTL3_EV_vs_WT_F06.06461.06461.2 0.0111 16-Jun K.EHHFGSSGM.T "sp|Q9Y2W1|TR150_HUMAN,tr|A0A3B3ITZ9|A0A3B3ITZ9_HUMAN" 2 987.3869 - 77179 6461 2 987.387075 494.7007 Thyroid hormone receptor-associated protein 3 OS=Homo sapiens OX=9606 GN=THRAP3 PE=1 SV=2 5.99 1621.9 - 673137 - - - 0.2127 - 1.176 0.375 - 126.7 1 1 0 0.0002 9 0 0 0 - - - - - 2.2797 0.9998 221125_WJC_METTL3_EV_vs_WT_F06.06469.06469.2 0.00644 14-Oct K.HAALSLSK[136.11].E "sp|Q9H0C8|ILKAP_HUMAN,tr|F8SNU7|F8SNU7_HUMAN,tr|H7C2I8|H7C2I8_HUMAN" 3 833.4851 0.14 77184 6469 2 833.484229 417.7498 Integrin-linked kinase-associated serine\threonine phosphatase 2C OS=Homo sapiens OX=9606 GN=ILKAP PE=1 SV=1 8.76 1622.8 - 1.65E+06 - - - -0.9874 - 2.081 0.416 - 334.6 1 2 0 -0.0008 8 0 0 0 5.11E+06 3.63E+07 - - - 4.3236 0.9999 221125_WJC_METTL3_EV_vs_WT_F06.06475.06475.3 0.000289 Oct-36 K.YMEENDQLK[136.11]K[136.11].G "sp|P51572|BAP31_HUMAN,tr|A0A2R8Y5M6|A0A2R8Y5M6_HUMAN,tr|C9J0M4|C9J0M4_HUMAN,tr|C9JQ75|C9JQ75_HUMAN,tr|C9JSP1|C9JSP1_HUMAN,tr|C9JMD7|C9JMD7_HUMAN" 6 1312.6304 1.06 77188 6475 3 1312.629327 438.5507 B-cell receptor-associated protein 31 OS=Homo sapiens OX=9606 GN=BCAP31 PE=1 SV=3 4.68 1623.6 - 1.74E+06 - - - -0.819 - 1.845 0.471 - 85.2 1 2 0 -0.0011 10 0 0 0 4.31E+07 4.06E+07 - - - 5.5796 0.9994 221125_WJC_METTL3_EV_vs_WT_F06.06479.06479.2 0.00919 18-Aug K.QQEQADSLER.S "sp|Q14980|NUMA1_HUMAN,tr|A0A087WY61|A0A087WY61_HUMAN" 2 1202.5527 1.41 77192 6479 2 1202.550523 602.2836 Nuclear mitotic apparatus protein 1 OS=Homo sapiens OX=9606 GN=NUMA1 PE=1 SV=2 4.14 1624 - 391351 - - - -1.8469 - 1.639 0.417 - 296 1 2 0 -0.0022 10 0 0 0 2.23E+07 1.58E+07 - - - 3.4994 0.9187 221125_WJC_METTL3_EV_vs_WT_F06.06486.06486.2 0.0457 14-Jun S.SSQSLEHR.L "sp|Q5H9F3|BCORL_HUMAN,tr|H7C4B2|H7C4B2_HUMAN" 2 942.4519 18.38 77197 6486 2 942.452869 472.2332 BCL-6 corepressor-like protein 1 OS=Homo sapiens OX=9606 GN=BCORL1 PE=1 SV=1 6.47 1624.8 - 345213 - - - 1.0197 - 1.383 0.307 - 139.5 1 1 0 0.001 8 0 0 0 5.78E+06 3.14E+05 - - - 2.2861 0.9997 221125_WJC_METTL3_EV_vs_WT_F06.06487.06487.2 0.00258 18-Sep R.LQEGSLSSSK.A "sp|Q9Y618|NCOR2_HUMAN,tr|C9J7T7|C9J7T7_HUMAN,tr|C9JE98|C9JE98_HUMAN,tr|C9J0Q5|C9J0Q5_HUMAN,tr|A0A384DVL6|A0A384DVL6_HUMAN" 5 1034.5244 1.83 77198 6487 2 1034.524893 518.2695 Nuclear receptor corepressor 2 OS=Homo sapiens OX=9606 GN=NCOR2 PE=1 SV=3 6 1624.9 - 1.46E+06 - - - 0.4727 - 1.869 0.398 - 232.8 1 2 0 0.0005 10 0 0 0 2.85E+07 1.56E+07 - - - 3.7262 0.9994 221125_WJC_METTL3_EV_vs_WT_F06.06490.06490.2 0.000988 16-Aug R.NC[160.03]GQEPTLK.T sp|Q96BD8|SKA1_HUMAN 1 1045.4862 5.45 77199 6490 2 1045.487809 523.7504 Spindle and kinetochore-associated protein 1 OS=Homo sapiens OX=9606 GN=SKA1 PE=1 SV=1 5.99 1625.3 - 932297 - - - 1.496 - 1.602 0.399 - 227.4 1 2 0 0.0016 9 0 0 0 1.89E+07 3.47E+06 - - - 3.3509 0.9999 221125_WJC_METTL3_EV_vs_WT_F06.06492.06492.2 3.82E-05 18-Sep K.AQC[160.03]EDDLAEK.R "sp|Q12797|ASPH_HUMAN,tr|A0A087WW51|A0A087WW51_HUMAN" 2 1177.4921 1.34 77201 6492 2 1177.491466 589.7533 Aspartyl\asparaginyl beta-hydroxylase OS=Homo sapiens OX=9606 GN=ASPH PE=1 SV=3 3.92 1625.4 - 1.12E+06 - - - -0.5537 - 1.915 0.551 - 349.8 1 2 0 -0.0007 10 0 0 0 1.78E+07 1.33E+07 - - - 4.924 0.9987 221125_WJC_METTL3_EV_vs_WT_F06.06493.06493.2 0.00328 18-Aug K.AQC[160.03]EDDLAEK[136.11].R "sp|Q12797|ASPH_HUMAN,tr|A0A087WW51|A0A087WW51_HUMAN" 2 1185.5063 1.34 77202 6493 2 1185.508917 593.7604 Aspartyl\asparaginyl beta-hydroxylase OS=Homo sapiens OX=9606 GN=ASPH PE=1 SV=3 3.92 1625.5 - 906995 - - - 2.1923 - 1.574 0.372 - 153.8 1 2 0 0.0026 10 0 0 0 1.78E+07 1.33E+07 - - - 3.054 0.9995 221125_WJC_METTL3_EV_vs_WT_F06.06495.06495.2 3.02E-05 18-Nov M.APTIQTQAQR.E sp|Q8N7H5|PAF1_HUMAN 1 1112.5938 0.75 77204 6495 2 1112.596989 557.3042 RNA polymerase II-associated factor 1 homolog OS=Homo sapiens OX=9606 GN=PAF1 PE=1 SV=2 9.79 1625.8 - 450989 - - - 2.8474 - 2.308 0.49 - 427.4 1 2 0 0.0032 10 0 0 0 2.51E+07 3.36E+07 - - - 4.9937 0.9998 221125_WJC_METTL3_EV_vs_WT_F06.06498.06498.2 0.000101 18-Sep K.YMEENDQLK[136.11]K[136.11].G "sp|P51572|BAP31_HUMAN,tr|A0A2R8Y5M6|A0A2R8Y5M6_HUMAN,tr|C9J0M4|C9J0M4_HUMAN,tr|C9JQ75|C9JQ75_HUMAN,tr|C9JSP1|C9JSP1_HUMAN,tr|C9JMD7|C9JMD7_HUMAN" 6 1312.6304 0.55 77207 6498 2 1312.629949 657.3225 B-cell receptor-associated protein 31 OS=Homo sapiens OX=9606 GN=BCAP31 PE=1 SV=3 4.68 1626.2 - 267016 - - - -0.3451 - 1.742 0.44 - 241.6 1 2 0 -0.0005 10 0 0 0 1.98E+06 3.63E+06 - - - 3.84 0.9999 221125_WJC_METTL3_EV_vs_WT_F06.06502.06502.2 0.0078 24-Dec K.SGAEVEAGDAAER[166.11].R "sp|Q8IY67|RAVR1_HUMAN,tr|K7EKR9|K7EKR9_HUMAN,tr|E9PAU2|E9PAU2_HUMAN,tr|A0A087WZ13|A0A087WZ13_HUMAN" 4 1270.5665 0.98 77209 6502 2 1270.566619 636.2905 Ribonucleoprotein PTB-binding 1 OS=Homo sapiens OX=9606 GN=RAVER1 PE=1 SV=1 4 1626.7 - 3.13E+06 - - - 0.0992 - 2.452 0.49 - 543.2 1 2 0 0.0001 13 0 0 0 1.59E+09 1.62E+09 - - - 4.962 0.9988 221125_WJC_METTL3_EV_vs_WT_F06.06503.06503.2 0.000114 12-Aug K.DHAVFTR[166.11].R sp|P31689|DNJA1_HUMAN 1 854.4274 0.83 77210 6503 2 854.427744 428.221 DnaJ homolog subfamily A member 1 OS=Homo sapiens OX=9606 GN=DNAJA1 PE=1 SV=2 6.74 1626.8 - 2.88E+06 - - - 0.378 - 1.644 0.221 - 396.5 1 2 0 0.0003 7 0 0 0 1.36E+08 1.64E+08 - - - 2.2484 0.9999 221125_WJC_METTL3_EV_vs_WT_F06.06504.06504.2 0.00103 24-Dec K.SGAEVEAGDAAER.R "sp|Q8IY67|RAVR1_HUMAN,tr|K7EKR9|K7EKR9_HUMAN,tr|E9PAU2|E9PAU2_HUMAN,tr|A0A087WZ13|A0A087WZ13_HUMAN" 4 1260.5582 0.98 77211 6504 2 1260.558362 631.2864 Ribonucleoprotein PTB-binding 1 OS=Homo sapiens OX=9606 GN=RAVER1 PE=1 SV=1 4 1626.8 - 2.57E+06 - - - 0.1103 - 2.627 0.521 - 603.2 1 2 0 0.0001 13 0 0 0 1.59E+09 1.62E+09 - - - 5.3679 0.9997 221125_WJC_METTL3_EV_vs_WT_F06.06505.06505.2 0.0604 16-Nov R.LQAQNIQQR.H "sp|Q9UK61|TASOR_HUMAN,tr|A0A087X0F1|A0A087X0F1_HUMAN" 2 1097.5942 0.3 77212 6505 2 1097.593846 549.8044 Protein TASOR OS=Homo sapiens OX=9606 GN=TASOR PE=1 SV=3 9.75 1626.9 - 979640 - - - -0.2815 - 2.273 0.291 - 489.2 1 2 0 -0.0003 9 0 0 0 1.93E+07 6.39E+07 - - - 3.5657 0.9964 221125_WJC_METTL3_EV_vs_WT_F06.06506.06506.3 0.0158 Oct-32 K.EESMK[136.11]ETLR[166.11].L "sp|P0CG22|DR4L1_HUMAN,sp|Q9BTZ2|DHRS4_HUMAN,tr|H0YNP7|H0YNP7_HUMAN,tr|F5GWZ1|F5GWZ1_HUMAN,tr|E9PFL3|E9PFL3_HUMAN,tr|A0A087WXI8|A0A087WXI8_HUMAN" 6 1139.5611 0.001 77213 6506 3 1139.56019 380.861 Putative dehydrogenase\reductase SDR family member 4-like 1 OS=Homo sapiens OX=9606 GN=DHRS4L1 PE=5 SV=1 4.79 1627 - 743850 - - - -0.8372 - 1.705 0.3 - 112.6 1 2 1 -0.001 9 0 0 0 0.00E+00 3.70E+07 - - - 3.4925 0.9997 221125_WJC_METTL3_EV_vs_WT_F06.06509.06509.2 0.000295 22-Nov K.EAEGAPQVEAGK[136.11].R "sp|Q05682|CALD1_HUMAN,tr|C9J813|C9J813_HUMAN,tr|E7EX44|E7EX44_HUMAN,tr|E9PGZ1|E9PGZ1_HUMAN" 4 1192.5815 0.25 77215 6509 2 1192.580199 597.298 Caldesmon OS=Homo sapiens OX=9606 GN=CALD1 PE=1 SV=3 4.25 1627.4 - 563428 - - - -1.1169 - 1.869 0.42 - 390.8 1 2 0 -0.0013 12 0 0 0 3.21E+06 1.27E+07 - - - 3.7882 0.9995 221125_WJC_METTL3_EV_vs_WT_F06.06511.06511.2 0.00153 14-Jul K.EHC[160.03]LVGVK[136.11].G sp|Q86U44|MTA70_HUMAN 1 948.4942 0.03 77216 6511 2 948.494655 475.2544 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 6.83 1627.6 - 1.02E+07 - - - 0.4407 - 1.337 0.436 - 179.4 1 2 0 0.0004 8 0 0 0 3.11E+08 1.07E+10 - - - 3.1371 0.9992 221125_WJC_METTL3_EV_vs_WT_F06.06512.06512.2 0.296 14/18 R.RVAAMSVAQR.V sp|O43143|DHX15_HUMAN 1 1087.592 0.86 77217 6512 2 1087.593189 544.8033 Pre-mRNA-splicing factor ATP-dependent RNA helicase DHX15 OS=Homo sapiens OX=9606 GN=DHX15 PE=1 SV=2 12 1627.7 - 1.50E+06 - - - 1.05 - 2.177 0.218 - 287.5 1 2 0 0.0011 10 0 0 0 5.12E+07 5.97E+07 - - - 2.8223 0.9998 221125_WJC_METTL3_EV_vs_WT_F06.06521.06521.2 0.00117 18-Oct K.ETEGDVTSVK[136.11].D sp|P50990|TCPQ_HUMAN 1 1071.5175 0.39 77225 6521 2 1071.518106 536.766 T-complex protein 1 subunit theta OS=Homo sapiens OX=9606 GN=CCT8 PE=1 SV=4 4.14 1628.7 - 3.78E+06 - - - 0.5338 - 1.985 0.426 - 499.8 1 2 0 0.0006 10 0 0 0 4.81E+08 1.22E+09 - - - 4.101 0.9407 221125_WJC_METTL3_EV_vs_WT_F06.06522.06522.2 0.0276 18-Jun K.YMEENDQLKK.G "sp|P51572|BAP31_HUMAN,tr|A0A2R8Y5M6|A0A2R8Y5M6_HUMAN,tr|C9J0M4|C9J0M4_HUMAN,tr|C9JQ75|C9JQ75_HUMAN,tr|C9JSP1|C9JSP1_HUMAN,tr|C9JMD7|C9JMD7_HUMAN" 6 1296.602 0.55 77226 6522 2 1296.609916 649.3083 B-cell receptor-associated protein 31 OS=Homo sapiens OX=9606 GN=BCAP31 PE=1 SV=3 4.68 1628.8 - 211497 - - - 6.1036 - 1.228 0.326 - 79.3 1 2 0 0.0079 10 0 0 0 1.98E+06 3.63E+06 - - - 2.0196 0.9991 221125_WJC_METTL3_EV_vs_WT_F06.06524.06524.2 0.0121 16-Sep K.GANPVEIRR.G "sp|P10809|CH60_HUMAN,tr|A0A7I2V2X6|A0A7I2V2X6_HUMAN,tr|A0A7I2YQK6|A0A7I2YQK6_HUMAN,tr|A0A7I2V599|A0A7I2V599_HUMAN,tr|E7EXB4|E7EXB4_HUMAN,tr|A0A7I2YQ71|A0A7I2YQ71_HUMAN,tr|E7ESH4|E7ESH4_HUMAN,tr|A0A7I2V5M1|A0A7I2V5M1_HUMAN,tr|A0A7I2V5K3|A0A7I2V5K3_HUMAN,tr|A0A7I2V369|A0A7I2V369_HUMAN" 10 1010.5621 1.17 77228 6524 2 1010.563101 506.2883 "60 kDa heat shock protein, mitochondrial OS=Homo sapiens OX=9606 GN=HSPD1 PE=1 SV=2" 9.6 1629 - 1.07E+06 - - - 0.9638 - 1.631 0.302 - 191.1 1 2 0 0.001 9 0 0 0 2.59E+08 2.21E+08 - - - 2.6865 0.9999 221125_WJC_METTL3_EV_vs_WT_F06.06535.06535.2 1.74E-05 22-Oct K.VAQGVSGAVQDK[136.11].G "sp|P12268|IMDH2_HUMAN,tr|A0A7I2YQK5|A0A7I2YQK5_HUMAN,tr|H0Y4R1|H0Y4R1_HUMAN,tr|A0A7I2V2T3|A0A7I2V2T3_HUMAN,tr|E7ETK5|E7ETK5_HUMAN" 5 1165.6183 0.71 77238 6535 2 1165.618479 583.8164 Inosine-5'-monophosphate dehydrogenase 2 OS=Homo sapiens OX=9606 GN=IMPDH2 PE=1 SV=2 5.81 1630.2 - 9.42E+06 - - - 0.1956 - 2.119 0.525 - 362.7 1 2 0 0.0002 12 0 0 0 2.41E+08 3.39E+08 - - - 4.8944 0.9972 221125_WJC_METTL3_EV_vs_WT_F06.06538.06538.3 0.0012 Oct-32 K.FDQK[136.11]QELGR[166.11].V "sp|P43243|MATR3_HUMAN,tr|B3KM87|B3KM87_HUMAN,tr|A8MXP9|A8MXP9_HUMAN,tr|D6RBK5|D6RBK5_HUMAN,tr|A0A0R4J2E8|A0A0R4J2E8_HUMAN,tr|H0Y8T4|H0Y8T4_HUMAN,tr|D6REM6|D6REM6_HUMAN" 7 1137.5897 0.001 77241 6538 3 1137.587988 380.2039 Matrin-3 OS=Homo sapiens OX=9606 GN=MATR3 PE=1 SV=2 6.07 1630.4 - 2.69E+06 - - - -1.5419 - 1.579 0.356 - 108.9 1 2 1 -0.0018 9 0 0 0 0.00E+00 1.41E+08 - - - 3.8852 0.9957 221125_WJC_METTL3_EV_vs_WT_F06.06539.06539.2 0.0419 16-Jul K.GANPVEIR[166.11]R[166.11].G "sp|P10809|CH60_HUMAN,tr|A0A7I2V2X6|A0A7I2V2X6_HUMAN,tr|A0A7I2YQK6|A0A7I2YQK6_HUMAN,tr|A0A7I2V599|A0A7I2V599_HUMAN,tr|E7EXB4|E7EXB4_HUMAN,tr|A0A7I2YQ71|A0A7I2YQ71_HUMAN,tr|E7ESH4|E7ESH4_HUMAN,tr|A0A7I2V5M1|A0A7I2V5M1_HUMAN,tr|A0A7I2V5K3|A0A7I2V5K3_HUMAN,tr|A0A7I2V369|A0A7I2V369_HUMAN" 10 1030.5787 1.17 77242 6539 2 1030.579418 516.2966 "60 kDa heat shock protein, mitochondrial OS=Homo sapiens OX=9606 GN=HSPD1 PE=1 SV=2" 9.6 1630.5 - 2.21E+06 - - - 0.7287 - 1.194 0.241 - 132.9 1 2 0 0.0008 9 0 0 0 2.59E+08 2.21E+08 - - - 1.3338 0.9997 221125_WJC_METTL3_EV_vs_WT_F06.06540.06540.2 0.00478 18-Oct M.APTIQTQAQR[166.11].E sp|Q8N7H5|PAF1_HUMAN 1 1122.6021 0.75 77243 6540 2 1122.602213 562.3083 RNA polymerase II-associated factor 1 homolog OS=Homo sapiens OX=9606 GN=PAF1 PE=1 SV=2 9.79 1630.6 - 1.10E+06 - - - 0.1087 - 2.022 0.367 - 512.1 1 2 0 0.0001 10 0 0 0 2.51E+07 3.36E+07 - - - 3.7169 0.9999 221125_WJC_METTL3_EV_vs_WT_F06.06544.06544.2 0.000627 20-Sep R.MEQQEMAQQER.K sp|Q96EU6|RRP36_HUMAN 1 1406.5918 1.62 77247 6544 2 1406.593023 704.3032 Ribosomal RNA processing protein 36 homolog OS=Homo sapiens OX=9606 GN=RRP36 PE=1 SV=1 4.25 1630.9 - 408287 - - - 0.8354 - 2.249 0.51 - 294.7 1 2 0 0.0012 11 0 0 0 1.12E+07 6.92E+06 - - - 5 1 221125_WJC_METTL3_EV_vs_WT_F06.06545.06545.2 1.59E-05 22-Oct Q.VVC[160.03]EATQC[160.03]PDTR.V "sp|Q14974|IMB1_HUMAN,tr|J3KTM9|J3KTM9_HUMAN" 2 1434.6231 1.6 77248 6545 2 1434.62158 718.3189 Importin subunit beta-1 OS=Homo sapiens OX=9606 GN=KPNB1 PE=1 SV=2 4.37 1631.1 - 309541 - - - -1.0937 - 2.288 0.628 - 366.5 1 1 0 -0.0016 12 0 0 0 2.94E+07 1.84E+07 - - - 5.8567 0.9999 221125_WJC_METTL3_EV_vs_WT_F06.06548.06548.2 9.24E-06 18-Dec K.EGEEEQAINR[166.11].Q "sp|Q9H583|HEAT1_HUMAN,tr|Q5T3Q7|Q5T3Q7_HUMAN" 2 1183.5345 1.44 77249 6548 2 1183.534013 592.7745 HEAT repeat-containing protein 1 OS=Homo sapiens OX=9606 GN=HEATR1 PE=1 SV=3 4.09 1631.5 - 1.24E+06 - - - -0.3819 - 2.668 0.444 - 870.7 1 2 0 -0.0005 10 0 0 0 2.45E+07 1.71E+07 - - - 5.0594 0.9997 221125_WJC_METTL3_EV_vs_WT_F06.06549.06549.2 0.000568 18-Oct R.EAQAQALQDR.V sp|Q5TZA2|CROCC_HUMAN 1 1128.5523 2.53 77250 6549 2 1128.553712 565.2835 Rootletin OS=Homo sapiens OX=9606 GN=CROCC PE=1 SV=1 4.37 1631.6 - 398838 - - - 1.2069 - 2.141 0.415 - 464.1 1 2 0 0.0014 10 0 0 0 8.51E+06 3.36E+06 - - - 4.2307 0.9999 221125_WJC_METTL3_EV_vs_WT_F06.06552.06552.2 1.07E-05 20-Nov R.MEQQEMAQQER[166.11].K sp|Q96EU6|RRP36_HUMAN 1 1416.6001 1.61 77253 6552 2 1416.59982 709.3073 Ribosomal RNA processing protein 36 homolog OS=Homo sapiens OX=9606 GN=RRP36 PE=1 SV=1 4.25 1632 - 398518 - - - -0.2104 - 2.292 0.493 - 565.6 1 2 0 -0.0003 11 0 0 0 1.12E+07 6.92E+06 - - - 4.926 0.9998 221125_WJC_METTL3_EV_vs_WT_F06.06556.06556.2 0.000298 18-Sep R.ESLSEEEAQK.M "sp|Q9BXP5|SRRT_HUMAN,tr|H7C3A1|H7C3A1_HUMAN" 2 1148.5197 1.13 77255 6556 2 1148.517904 575.2671 Serrate RNA effector molecule homolog OS=Homo sapiens OX=9606 GN=SRRT PE=1 SV=1 4.09 1632.6 - 2.60E+06 - - - -1.5751 - 2.027 0.523 - 277.7 1 2 0 -0.0018 10 0 0 0 1.96E+08 1.74E+08 - - - 4.8755 0.9998 221125_WJC_METTL3_EV_vs_WT_F06.06558.06558.2 0.000778 18-Sep R.ESLSEEEAQK[136.11].M "sp|Q9BXP5|SRRT_HUMAN,tr|H7C3A1|H7C3A1_HUMAN" 2 1156.5339 1.13 77257 6558 2 1156.532812 579.2742 Serrate RNA effector molecule homolog OS=Homo sapiens OX=9606 GN=SRRT PE=1 SV=1 4.09 1632.7 - 2.69E+06 - - - -0.952 - 1.975 0.478 - 279.7 1 2 0 -0.0011 10 0 0 0 1.96E+08 1.74E+08 - - - 4.4708 0.9985 221125_WJC_METTL3_EV_vs_WT_F06.06560.06560.2 1.65E-05 16-Oct K.FDQK[136.11]QELGR[166.11].V "sp|P43243|MATR3_HUMAN,tr|B3KM87|B3KM87_HUMAN,tr|A8MXP9|A8MXP9_HUMAN,tr|D6RBK5|D6RBK5_HUMAN,tr|A0A0R4J2E8|A0A0R4J2E8_HUMAN,tr|H0Y8T4|H0Y8T4_HUMAN,tr|D6REM6|D6REM6_HUMAN" 7 1137.5897 0.74 77259 6560 2 1137.59037 569.8021 Matrin-3 OS=Homo sapiens OX=9606 GN=MATR3 PE=1 SV=2 6.07 1632.9 - 1.35E+06 - - - 0.552 - 2.125 0.5 - 487.4 1 2 1 0.0006 9 0 0 0 3.23E+07 4.39E+07 - - - 4.9145 1 221125_WJC_METTL3_EV_vs_WT_F06.06564.06564.2 1.03E-06 14/22 Q.VVC[160.03]EATQC[160.03]PDTR[166.11].V "sp|Q14974|IMB1_HUMAN,tr|J3KTM9|J3KTM9_HUMAN" 2 1444.6314 1.6 77261 6564 2 1444.629704 723.323 Importin subunit beta-1 OS=Homo sapiens OX=9606 GN=KPNB1 PE=1 SV=2 4.37 1633.4 - 966823 - - - -1.1872 - 2.667 0.6 - 841.8 1 1 0 -0.0017 12 0 0 0 2.94E+07 1.84E+07 - - - 6.0531 0.9996 221125_WJC_METTL3_EV_vs_WT_F06.06565.06565.2 1.81E-05 18-Nov R.ETQSQLETER.S sp|P15924|DESP_HUMAN 1 1219.5681 72.53 77262 6565 2 1219.568258 610.7913 Desmoplakin OS=Homo sapiens OX=9606 GN=DSP PE=1 SV=3 4.25 1633.5 - 1.29E+06 - - - 0.1624 - 2.022 0.304 - 660.7 1 2 0 0.0002 10 0 0 0 5.32E+08 7.34E+06 - - - 3.2516 0.9941 221125_WJC_METTL3_EV_vs_WT_F06.06578.06578.2 0.172 12-Jun K.YEDEINK.R "sp|P48668|K2C6C_HUMAN,sp|P05787|K2C8_HUMAN,sp|Q01546|K22O_HUMAN,sp|Q7Z794|K2C1B_HUMAN,sp|P12035|K2C3_HUMAN,sp|P04264|K2C1_HUMAN,sp|P04259|K2C6B_HUMAN,sp|P13647|K2C5_HUMAN,sp|P35908|K22E_HUMAN,sp|O95678|K2C75_HUMAN,sp|Q5XKE5|K2C79_HUMAN,sp|P02538|K2C6A_HUMAN,tr|F8VUG2|F8VUG2_HUMAN,tr|F8W0C6|F8W0C6_HUMAN,tr|F8VP67|F8VP67_HUMAN,tr|F8W1U3|F8W1U3_HUMAN,tr|H0YIN9|H0YIN9_HUMAN" 17 909.408 208.92 77269 6578 2 909.406523 455.7113 "Keratin, type II cytoskeletal 6C OS=Homo sapiens OX=9606 GN=KRT6C PE=1 SV=3" 4.14 1635.1 - 1.33E+06 - - - -1.5988 - 1.154 0.25 - 92.5 1 2 0 -0.0015 7 0 0 0 2.49E+07 1.19E+05 - - - 1.3409 0.967 221125_WJC_METTL3_EV_vs_WT_F06.06583.06583.2 0.0774 12-Jul R.YHEAWQK[136.11].L "sp|P17812|PYRG1_HUMAN,tr|A0A3B3ITF6|A0A3B3ITF6_HUMAN,tr|B4E1E0|B4E1E0_HUMAN,tr|A0A3B3IRQ8|A0A3B3IRQ8_HUMAN,tr|A0A3B3IRI2|A0A3B3IRI2_HUMAN" 5 968.4596 0.43 77272 6583 2 968.455286 485.2371 CTP synthase 1 OS=Homo sapiens OX=9606 GN=CTPS1 PE=1 SV=2 6.75 1635.7 - 845685 - - - -4.4194 - 1.26 0.242 - 228.8 1 2 0 -0.0043 7 0 0 0 1.28E+07 2.98E+07 - - - 1.5594 0.9993 221125_WJC_METTL3_EV_vs_WT_F06.06587.06587.2 0.000445 20-Sep K.VEVSEDEPASK[136.11].A sp|O75683|SURF6_HUMAN 1 1196.5652 1.14 77274 6587 2 1196.564457 599.2899 Surfeit locus protein 6 OS=Homo sapiens OX=9606 GN=SURF6 PE=1 SV=3 4 1636.2 - 286918 - - - -0.6318 - 1.629 0.325 - 301.1 1 2 0 -0.0008 11 0 0 0 7.63E+06 6.72E+06 - - - 2.7613 0.9994 221125_WJC_METTL3_EV_vs_WT_F06.06595.06595.2 0.00205 16-Oct R.QVDQLTNDK[136.11].A "sp|P08670|VIME_HUMAN,tr|B0YJC4|B0YJC4_HUMAN" 2 1067.5339 1.79 77280 6595 2 1067.534054 534.7742 Vimentin OS=Homo sapiens OX=9606 GN=VIM PE=1 SV=4 4.21 1637.2 - 747531 - - - 0.1883 - 1.757 0.29 - 333.8 1 2 0 0.0002 9 0 0 0 3.00E+09 1.68E+09 - - - 2.8134 0.9991 221125_WJC_METTL3_EV_vs_WT_F06.06606.06606.2 0.0926 14-Sep K.HLIPQESR.R "sp|Q6W2J9|BCOR_HUMAN,tr|H7BZ37|H7BZ37_HUMAN,tr|H7C2V9|H7C2V9_HUMAN,tr|H7C231|H7C231_HUMAN" 4 978.5247 1.47 77287 6606 2 978.524543 490.2696 BCL-6 corepressor OS=Homo sapiens OX=9606 GN=BCOR PE=1 SV=1 6.75 1638.6 - 464294 - - - -0.139 - 1.817 0.216 - 432.5 1 2 0 -0.0001 8 0 0 0 2.33E+08 1.59E+08 - - - 2.4374 0.9998 221125_WJC_METTL3_EV_vs_WT_F06.06609.06609.2 6.21E-06 22-Nov K.VSDGGSSSTDFK[136.11].M "sp|Q7Z6Z7|HUWE1_HUMAN,tr|A0A087X146|A0A087X146_HUMAN,tr|H0Y659|H0Y659_HUMAN" 3 1193.5292 0.64 77289 6609 2 1193.526971 597.7719 E3 ubiquitin-protein ligase HUWE1 OS=Homo sapiens OX=9606 GN=HUWE1 PE=1 SV=3 4.21 1638.9 - 349553 - - - -1.8349 - 2.187 0.583 - 432.5 1 2 0 -0.0022 12 0 0 0 7.94E+06 1.25E+07 - - - 5.4053 0.9952 221125_WJC_METTL3_EV_vs_WT_F06.06611.06611.2 0.0393 20-Jul R.SSSTEPPPPVR[166.11].Q "sp|Q8N684|CPSF7_HUMAN,tr|C9J323|C9J323_HUMAN,tr|F5H047|F5H047_HUMAN,tr|F5H669|F5H669_HUMAN,tr|F5H6M0|F5H6M0_HUMAN,tr|F5H5B7|F5H5B7_HUMAN,tr|J3QT54|J3QT54_HUMAN,tr|F5H2K8|F5H2K8_HUMAN,tr|F5GXA3|F5GXA3_HUMAN,tr|F5H1W4|F5H1W4_HUMAN,tr|F5H6A8|F5H6A8_HUMAN,tr|C9JM38|C9JM38_HUMAN,tr|C9J286|C9J286_HUMAN,tr|F5H6P5|F5H6P5_HUMAN" 14 1162.5858 0.69 77291 6611 2 1162.584425 582.3002 Cleavage and polyadenylation specificity factor subunit 7 OS=Homo sapiens OX=9606 GN=CPSF7 PE=1 SV=1 5.72 1639.2 - 483311 - - - -1.1586 - 1.203 0.241 - 118.6 1 2 0 -0.0013 11 0 0 0 9.91E+06 1.44E+07 - - - 1.3206 0.9998 221125_WJC_METTL3_EV_vs_WT_F06.06614.06614.2 0.000137 13/22 R.IEGDPQGVQQAK[136.11].R "sp|Q00341|VIGLN_HUMAN,tr|A0A024R4E5|A0A024R4E5_HUMAN,tr|H0Y394|H0Y394_HUMAN" 3 1276.6503 1.29 77292 6614 2 1276.649529 639.3324 Vigilin OS=Homo sapiens OX=9606 GN=HDLBP PE=1 SV=2 4.37 1639.6 - 1.43E+06 - - - -0.5883 - 2 0.45 - 407.8 1 2 0 -0.0008 12 0 0 0 1.60E+08 1.24E+08 - - - 4.1883 0.9999 221125_WJC_METTL3_EV_vs_WT_F06.06621.06621.2 8.09E-05 16-Jul R.DANDPVDDR.H sp|O94906|PRP6_HUMAN 1 1015.4207 2.72 77297 6621 2 1015.419598 508.7176 Pre-mRNA-processing factor 6 OS=Homo sapiens OX=9606 GN=PRPF6 PE=1 SV=1 3.77 1640.3 - 3.02E+06 - - - -1.0528 - 1.894 0.541 - 225.1 1 2 0 -0.0011 9 0 0 0 2.62E+08 9.63E+07 - - - 4.8843 0.9724 221125_WJC_METTL3_EV_vs_WT_F06.06624.06624.2 0.0186 14-Jul K.HLIPQESR[166.11].R "sp|Q6W2J9|BCOR_HUMAN,tr|H7BZ37|H7BZ37_HUMAN,tr|H7C2V9|H7C2V9_HUMAN,tr|H7C231|H7C231_HUMAN" 4 988.5329 1.49 77300 6624 2 988.532961 495.2738 BCL-6 corepressor OS=Homo sapiens OX=9606 GN=BCOR PE=1 SV=1 6.75 1640.5 - 1.05E+06 - - - 0.0121 - 1.395 0.005 - 237.2 2 2 0 0 8 0 0 0 2.43E+08 1.63E+08 - - - -0.0526 0.9997 221125_WJC_METTL3_EV_vs_WT_F06.06630.06630.2 0.000774 24-Nov R.SAAEPVASTPASR[166.11].L "sp|P49674|KC1E_HUMAN,tr|H0Y5S9|H0Y5S9_HUMAN,tr|H0Y682|H0Y682_HUMAN" 3 1252.6287 1.81 77305 6630 2 1252.625992 627.3216 Casein kinase I isoform epsilon OS=Homo sapiens OX=9606 GN=CSNK1E PE=1 SV=1 5.72 1641.3 - 278440 - - - -2.1619 - 2.58 0.477 - 448.4 1 2 0 -0.0027 13 0 0 0 6.56E+07 3.61E+07 - - - 4.9958 0.9998 221125_WJC_METTL3_EV_vs_WT_F06.06633.06633.2 0.00878 22-Nov R.IEGDPQGVQQAK.R "sp|Q00341|VIGLN_HUMAN,tr|A0A024R4E5|A0A024R4E5_HUMAN,tr|H0Y394|H0Y394_HUMAN" 3 1268.6361 1.29 77307 6633 2 1268.636012 635.3253 Vigilin OS=Homo sapiens OX=9606 GN=HDLBP PE=1 SV=2 4.37 1641.6 - 3.11E+06 - - - -0.0536 - 1.974 0.401 - 395.8 1 2 0 -0.0001 12 0 0 0 1.60E+08 1.24E+08 - - - 3.7921 0.9999 221125_WJC_METTL3_EV_vs_WT_F06.06634.06634.2 0.000111 16-Sep R.DANDPVDDR[166.11].H sp|O94906|PRP6_HUMAN 1 1025.4289 2.76 77308 6634 2 1025.429506 513.7217 Pre-mRNA-processing factor 6 OS=Homo sapiens OX=9606 GN=PRPF6 PE=1 SV=1 3.77 1641.6 - 1.43E+06 - - - 0.5549 - 2.051 0.605 - 409.1 1 2 0 0.0006 9 0 0 0 2.61E+08 9.45E+07 - - - 5.5875 0.9919 221125_WJC_METTL3_EV_vs_WT_F06.06635.06635.3 0.0349 Sep-40 R.VFNGSGK[136.11]PIDR[166.11].G "sp|P21281|VATB2_HUMAN,tr|H0YC04|H0YC04_HUMAN" 2 1206.6476 2.78 77309 6635 3 1206.645601 403.2231 "V-type proton ATPase subunit B, brain isoform OS=Homo sapiens OX=9606 GN=ATP6V1B2 PE=1 SV=3" 8.72 1641.7 - 652132 - - - -1.6492 - 1.46 0.24 - 74.3 2 2 0 -0.002 11 0 0 0 8.82E+07 3.18E+07 - - - 2.151 0.9736 221125_WJC_METTL3_EV_vs_WT_F06.06636.06636.2 0.301 18-Sep R.QLTPPEGSSK[136.11].S "sp|Q99613|EIF3C_HUMAN,sp|B5ME19|EIFCL_HUMAN" 2 1050.5437 0.63 77310 6636 2 1050.547548 526.2791 Eukaryotic translation initiation factor 3 subunit C OS=Homo sapiens OX=9606 GN=EIF3C PE=1 SV=1 6 1641.8 - 495970 - - - 3.6733 - 1.406 0.183 - 228.8 1 2 0 0.0039 10 0 0 0 2.89E+07 4.59E+07 - - - 1.3426 0.9876 221125_WJC_METTL3_EV_vs_WT_F06.06643.06643.2 1.49 12-Jun K.RYEEIVK.E "sp|P68104|EF1A1_HUMAN,sp|Q5VTE0|EF1A3_HUMAN,tr|A0A7I2V659|A0A7I2V659_HUMAN,tr|A0A7I2V3H3|A0A7I2V3H3_HUMAN,tr|A0A7I2V5N4|A0A7I2V5N4_HUMAN,tr|A0A087WVQ9|A0A087WVQ9_HUMAN,tr|A0A087WV01|A0A087WV01_HUMAN" 7 935.5076 0.65 77315 6643 2 935.508203 468.7611 Elongation factor 1-alpha 1 OS=Homo sapiens OX=9606 GN=EEF1A1 PE=1 SV=1 6.14 1642.6 - 743742 - - - 0.6104 - 1.197 0.128 - 136.9 1 2 0 0.0006 7 0 0 0 2.03E+07 3.14E+07 - - - 0.556 0.9945 221125_WJC_METTL3_EV_vs_WT_F06.06644.06644.2 0.0524 14-Aug K.QHVSIIEK[136.11].E sp|Q16850|CP51A_HUMAN 1 960.5484 1.32 77316 6644 2 960.548451 481.2815 Lanosterol 14-alpha demethylase OS=Homo sapiens OX=9606 GN=CYP51A1 PE=1 SV=4 6.75 1642.7 - 609738 - - - 0.0729 - 1.552 0.091 - 186.6 1 2 0 0.0001 8 0 0 0 2.04E+07 1.55E+07 - - - 1.0387 0.9992 221125_WJC_METTL3_EV_vs_WT_F06.06655.06655.2 0.00237 20-Sep R.SSSTEPPPPVR.Q "sp|Q8N684|CPSF7_HUMAN,tr|C9J323|C9J323_HUMAN,tr|F5H047|F5H047_HUMAN,tr|F5H669|F5H669_HUMAN,tr|F5H6M0|F5H6M0_HUMAN,tr|F5H5B7|F5H5B7_HUMAN,tr|J3QT54|J3QT54_HUMAN,tr|F5H2K8|F5H2K8_HUMAN,tr|F5GXA3|F5GXA3_HUMAN,tr|F5H1W4|F5H1W4_HUMAN,tr|F5H6A8|F5H6A8_HUMAN,tr|C9JM38|C9JM38_HUMAN,tr|C9J286|C9J286_HUMAN,tr|F5H6P5|F5H6P5_HUMAN" 14 1152.5775 1.05 77325 6655 2 1152.578145 577.296 Cleavage and polyadenylation specificity factor subunit 7 OS=Homo sapiens OX=9606 GN=CPSF7 PE=1 SV=1 5.72 1643.8 - 540611 - - - 0.5579 - 1.504 0.341 - 184.5 1 2 0 0.0006 11 0 0 0 4.53E+07 4.34E+07 - - - 2.6635 0.9998 221125_WJC_METTL3_EV_vs_WT_F06.06658.06658.2 0.0278 22-Nov K.AGLSPANC[160.03]QSDR[166.11].V sp|Q14692|BMS1_HUMAN 1 1284.5756 8.46 77328 6658 2 1284.576711 643.2951 Ribosome biogenesis protein BMS1 homolog OS=Homo sapiens OX=9606 GN=BMS1 PE=1 SV=1 5.87 1644.2 - 321007 - - - 0.8509 - 2.118 0.416 - 420.1 1 2 0 0.0011 12 0 0 0 1.44E+08 1.71E+07 - - - 4.0879 0.9922 221125_WJC_METTL3_EV_vs_WT_F06.06667.06667.2 0.152 16-Jun K.STEEQELEK.S sp|Q9ULW0|TPX2_HUMAN 1 1091.4982 0.1 77335 6667 2 1091.50224 546.7564 Targeting protein for Xklp2 OS=Homo sapiens OX=9606 GN=TPX2 PE=1 SV=2 4.09 1645.1 - 613254 - - - 3.6564 - 1.46 0.295 - 141.6 1 2 0 0.004 9 0 0 0 1.40E+07 1.40E+08 - - - 2.3135 1 221125_WJC_METTL3_EV_vs_WT_F06.06669.06669.2 0.000104 19/26 K.K[136.11]GPGEVAGTVTGQK[136.11].R "sp|Q86U44|MTA70_HUMAN,tr|F5H6D8|F5H6D8_HUMAN,tr|H0YFV6|H0YFV6_HUMAN,tr|B4DTN4|B4DTN4_HUMAN" 4 1343.738 0 77336 6669 2 1343.737949 672.8763 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 8.59 1645.3 - 4.99E+06 - - - -0.0223 - 3.476 0.597 - 925.4 1 2 0 0 14 0 0 0 8.15E+05 1.69E+08 - - - 6.5769 0.9997 221125_WJC_METTL3_EV_vs_WT_F06.06671.06671.3 7.92E-05 Oct-32 K.YEK[136.11]DVADYK[136.11].S "sp|O15347|HMGB3_HUMAN,tr|E7EQU1|E7EQU1_HUMAN,tr|E7ES08|E7ES08_HUMAN" 3 1145.5576 0.001 77337 6671 3 1145.556914 382.8598 High mobility group protein B3 OS=Homo sapiens OX=9606 GN=HMGB3 PE=1 SV=4 4.56 1645.5 - 3.49E+06 - - - -0.5596 - 2.144 0.43 - 119.1 1 2 1 -0.0006 9 0 0 0 0.00E+00 6.92E+07 - - - 5.6324 0.9997 221125_WJC_METTL3_EV_vs_WT_F06.06672.06672.2 0.0018 14-Jul K.YHSDEYIK.F "sp|Q92769|HDAC2_HUMAN,tr|E5RHE7|E5RHE7_HUMAN,tr|E5RGV4|E5RGV4_HUMAN,tr|H3BM24|H3BM24_HUMAN,tr|E5RJ04|E5RJ04_HUMAN,tr|E5RG37|E5RG37_HUMAN,tr|E5RH52|E5RH52_HUMAN,tr|E5RK19|E5RK19_HUMAN,tr|E5RFP9|E5RFP9_HUMAN,tr|E5RFI6|E5RFI6_HUMAN" 10 1053.4767 2.43 77338 6672 2 1053.47833 527.7456 Histone deacetylase 2 OS=Homo sapiens OX=9606 GN=HDAC2 PE=1 SV=2 5.32 1645.6 - 1.68E+06 - - - 1.5235 - 1.419 0.54 - 166.3 1 2 0 0.0016 8 0 0 0 1.73E+08 7.11E+07 - - - 4.0844 0.9985 221125_WJC_METTL3_EV_vs_WT_F06.06674.06674.2 0.563 16-Aug K.ALTTPTHYK.L "sp|P52948|NUP98_HUMAN,tr|A0A3B3ITD8|A0A3B3ITD8_HUMAN,tr|H0YEN4|H0YEN4_HUMAN,tr|H0YCR0|H0YCR0_HUMAN" 4 1030.5447 1.23 77340 6674 2 1030.543617 516.2796 Nuclear pore complex protein Nup98-Nup96 OS=Homo sapiens OX=9606 GN=NUP98 PE=1 SV=4 8.64 1645.7 - 1.17E+06 - - - -1.0946 - 1.566 0.27 - 231.3 2 2 0 -0.0011 9 0 0 0 8.32E+07 6.79E+07 - - - 2.198 0.9987 221125_WJC_METTL3_EV_vs_WT_F06.06675.06675.2 0.000111 16-Nov K.YEK[136.11]DVADYK[136.11].S "sp|O15347|HMGB3_HUMAN,tr|E7EQU1|E7EQU1_HUMAN,tr|E7ES08|E7ES08_HUMAN" 3 1145.5576 0.03 77341 6675 2 1145.558521 573.7861 High mobility group protein B3 OS=Homo sapiens OX=9606 GN=HMGB3 PE=1 SV=4 4.56 1645.9 - 769107 - - - 0.8433 - 2.238 0.541 - 414.1 1 2 1 0.001 9 0 0 0 4.60E+05 1.55E+07 - - - 5.3671 0.9947 221125_WJC_METTL3_EV_vs_WT_F06.06676.06676.2 8.77E-08 16/30 V.AAATTAAPAAAAAPAK[136.11].V "sp|P05388|RLA0_HUMAN,tr|F8VWS0|F8VWS0_HUMAN,tr|F8W1K8|F8W1K8_HUMAN" 3 1331.7289 1.4 77342 6676 2 1331.729309 666.8717 60S acidic ribosomal protein P0 OS=Homo sapiens OX=9606 GN=RPLP0 PE=1 SV=1 8.8 1646 - 690084 - - - 0.3342 - 2.611 0.571 - 687.9 1 1 0 0.0004 16 0 0 0 3.46E+07 2.48E+07 - - - 5.6178 0.9985 221125_WJC_METTL3_EV_vs_WT_F06.06679.06679.2 0.00219 20-Aug R.NPPPNSDPNLR[166.11].R sp|Q96I24|FUBP3_HUMAN 1 1229.6028 1.71 77343 6679 2 1229.602738 615.8087 Far upstream element-binding protein 3 OS=Homo sapiens OX=9606 GN=FUBP3 PE=1 SV=2 5.84 1646.4 - 5.74E+06 - - - -0.0659 - 1.798 0.186 - 226.6 1 2 0 -0.0001 11 0 0 0 4.32E+08 2.53E+08 - - - 2.0019 1 221125_WJC_METTL3_EV_vs_WT_F06.06680.06680.2 1.45E-09 17/30 V.AAATTAAPAAAAAPAK.V "sp|P05388|RLA0_HUMAN,tr|F8VWS0|F8VWS0_HUMAN,tr|F8W1K8|F8W1K8_HUMAN" 3 1323.7147 1.4 77344 6680 2 1323.714169 662.8646 60S acidic ribosomal protein P0 OS=Homo sapiens OX=9606 GN=RPLP0 PE=1 SV=1 8.8 1646.5 - 1.20E+06 - - - -0.3739 - 2.718 0.592 - 830.8 1 1 0 -0.0005 16 0 0 0 3.46E+07 2.48E+07 - - - 5.8716 0.999 221125_WJC_METTL3_EV_vs_WT_F06.06685.06685.3 0.0111 Nov-48 K.GLGATTHPTAAVK[136.11].M "sp|P52789|HXK2_HUMAN,tr|E9PB90|E9PB90_HUMAN" 2 1230.6812 0.87 77347 6685 3 1230.679295 411.2343 Hexokinase-2 OS=Homo sapiens OX=9606 GN=HK2 PE=1 SV=2 8.76 1647.1 - 941493 - - - -1.5365 - 2.156 0.272 - 99.4 2 2 0 -0.0019 13 0 0 0 1.30E+07 1.50E+07 - - - 3.5156 0.9987 221125_WJC_METTL3_EV_vs_WT_F06.06692.06692.2 0.00421 20-Aug R.VFNGSGKPIDR.G "sp|P21281|VATB2_HUMAN,tr|H0YC04|H0YC04_HUMAN" 2 1188.6251 0.75 77352 6692 2 1188.627741 595.3198 "V-type proton ATPase subunit B, brain isoform OS=Homo sapiens OX=9606 GN=ATP6V1B2 PE=1 SV=3" 8.72 1648 - 419327 - - - 2.2042 - 1.574 0.373 - 244.5 1 2 0 0.0026 11 0 0 0 7.90E+06 1.05E+07 - - - 3.0223 0.996 221125_WJC_METTL3_EV_vs_WT_F06.06697.06697.2 0.0237 12-Aug R.NNLIQQK[136.11].N "sp|Q9NR56|MBNL1_HUMAN,sp|Q5VZF2|MBNL2_HUMAN,sp|Q9NUK0|MBNL3_HUMAN,tr|H7C4T5|H7C4T5_HUMAN,tr|Q86VM6|Q86VM6_HUMAN,tr|C9J4T8|C9J4T8_HUMAN,tr|A0A0A0MQX8|A0A0A0MQX8_HUMAN,tr|A0A7P0T9I3|A0A7P0T9I3_HUMAN,tr|B1AKI6|B1AKI6_HUMAN,tr|C9JP00|C9JP00_HUMAN,tr|O95205|O95205_HUMAN" 11 864.4909 2.36 77355 6697 2 864.489135 433.2527 Muscleblind-like protein 1 OS=Homo sapiens OX=9606 GN=MBNL1 PE=1 SV=2 8.75 1648.7 - 736073 - - - -2.0023 - 1.586 0.182 - 323.8 1 2 0 -0.0017 7 0 0 0 3.62E+07 1.53E+07 - - - 1.8461 0.9993 221125_WJC_METTL3_EV_vs_WT_F06.06701.06701.2 0.0169 20-Sep R.NPPPNSDPNLR.R sp|Q96I24|FUBP3_HUMAN 1 1219.5945 1.82 77358 6701 2 1219.59439 610.8046 Far upstream element-binding protein 3 OS=Homo sapiens OX=9606 GN=FUBP3 PE=1 SV=2 5.84 1649.1 - 1.46E+07 - - - -0.1304 - 1.867 0.269 - 259 1 2 0 -0.0002 11 0 0 0 4.09E+08 2.25E+08 - - - 2.7168 0.9987 221125_WJC_METTL3_EV_vs_WT_F06.06704.06704.2 0.0209 18-Sep K.VQLGDQTDSK[136.11].M "sp|Q9NU22|MDN1_HUMAN,tr|Q5T795|Q5T795_HUMAN" 2 1097.5444 0.68 77361 6704 2 1097.546001 549.7795 Midasin OS=Homo sapiens OX=9606 GN=MDN1 PE=1 SV=2 4.21 1649.3 - 1.05E+06 - - - 1.4423 - 1.586 0.307 - 307.5 1 2 0 0.0016 10 0 0 0 1.81E+07 2.66E+07 - - - 2.5954 0.9998 221125_WJC_METTL3_EV_vs_WT_F06.06706.06706.2 0.0497 13/22 R.FGGSGSQVDSAR[166.11].M sp|Q13200|PSMD2_HUMAN 1 1176.5399 0.63 77363 6706 2 1176.537736 589.2772 26S proteasome non-ATPase regulatory subunit 2 OS=Homo sapiens OX=9606 GN=PSMD2 PE=1 SV=3 5.84 1649.5 - 512880 - - - -1.8265 - 2.374 0.472 - 449.4 1 2 0 -0.0021 12 0 0 0 7.17E+07 1.14E+08 - - - 4.8014 0.7932 221125_WJC_METTL3_EV_vs_WT_F06.06707.06707.2 3.4 14-Jun P.K[136.11]VSEQLLK[136.11].L "sp|Q9P2F8|SI1L2_HUMAN,tr|A0A6Q8PGD5|A0A6Q8PGD5_HUMAN,tr|A0A6Q8PH54|A0A6Q8PH54_HUMAN,tr|A0A6Q8PFQ0|A0A6Q8PFQ0_HUMAN" 4 959.5986 0.001 77364 6707 2 959.598971 480.8066 Signal-induced proliferation-associated 1-like protein 2 OS=Homo sapiens OX=9606 GN=SIPA1L2 PE=1 SV=2 8.59 1649.6 - 354195 - - - 0.3533 - 1.431 0.17 - 125.2 2 1 0 0.0003 8 0 0 0 0.00E+00 4.43E+07 - - - 1.2429 1 221125_WJC_METTL3_EV_vs_WT_F06.06712.06712.2 3.74E-06 22-Dec R.GFSDSGGGPPAK.Q "sp|Q9H307|PININ_HUMAN,tr|G3V5F0|G3V5F0_HUMAN,tr|G3V579|G3V579_HUMAN" 3 1075.4934 1.61 77367 6712 2 1075.492854 538.754 Pinin OS=Homo sapiens OX=9606 GN=PNN PE=1 SV=5 5.84 1650.2 - 1.57E+06 - - - -0.543 - 2.457 0.597 - 390.9 1 2 0 -0.0006 12 0 0 0 2.88E+08 1.80E+08 - - - 5.8155 0.9998 221125_WJC_METTL3_EV_vs_WT_F06.06714.06714.2 0.000134 22-Dec R.GFSDSGGGPPAK[136.11].Q "sp|Q9H307|PININ_HUMAN,tr|G3V5F0|G3V5F0_HUMAN,tr|G3V579|G3V579_HUMAN" 3 1083.5076 1.64 77369 6714 2 1083.507017 542.7611 Pinin OS=Homo sapiens OX=9606 GN=PNN PE=1 SV=5 5.84 1650.3 - 1.07E+06 - - - -0.5731 - 1.954 0.506 - 394 1 2 0 -0.0006 12 0 0 0 2.95E+08 1.80E+08 - - - 4.5407 0.9987 221125_WJC_METTL3_EV_vs_WT_F06.06716.06716.2 0.0051 18-Aug R.SSGAPETLQR.V sp|Q9BW92|SYTM_HUMAN 1 1044.52 0.62 77371 6716 2 1044.52207 523.2673 "Threonine--tRNA ligase, mitochondrial OS=Homo sapiens OX=9606 GN=TARS2 PE=1 SV=1" 5.72 1650.5 - 927863 - - - 1.9942 - 1.511 0.372 - 273.4 1 2 0 0.0021 10 0 0 0 1.93E+07 3.10E+07 - - - 2.9401 1 221125_WJC_METTL3_EV_vs_WT_F06.06722.06722.2 9.20E-06 13/22 R.FGGSGSQVDSAR.M sp|Q13200|PSMD2_HUMAN 1 1166.5316 0.63 77375 6722 2 1166.5304 584.2731 26S proteasome non-ATPase regulatory subunit 2 OS=Homo sapiens OX=9606 GN=PSMD2 PE=1 SV=3 5.84 1651.3 - 1.23E+06 - - - -1.0415 - 2.579 0.589 - 479.3 1 2 0 -0.0012 12 0 0 0 7.17E+07 1.14E+08 - - - 5.8837 1 221125_WJC_METTL3_EV_vs_WT_F06.06728.06728.3 8.85E-05 13/52 K.K[136.11]GPGEVAGTVTGQK[136.11].R "sp|Q86U44|MTA70_HUMAN,tr|F5H6D8|F5H6D8_HUMAN,tr|H0YFV6|H0YFV6_HUMAN,tr|B4DTN4|B4DTN4_HUMAN" 4 1343.738 0.01 77380 6728 3 1343.738127 448.9199 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 8.59 1651.9 - 1.21E+07 - - - 0.1101 - 2.933 0.557 - 275.4 1 2 0 0.0001 14 0 0 0 3.92E+06 5.86E+08 - - - 7.6095 0.9945 221125_WJC_METTL3_EV_vs_WT_F06.06731.06731.2 0.0338 18-Jul K.DQLPADEC[160.03]NK[136.11].L "sp|P38646|GRP75_HUMAN,tr|A0A7I2V2S7|A0A7I2V2S7_HUMAN,tr|A0A7I2V2G2|A0A7I2V2G2_HUMAN,tr|A0A7I2V3F7|A0A7I2V3F7_HUMAN,tr|A0A7I2YQB2|A0A7I2YQB2_HUMAN,tr|D6RCD7|D6RCD7_HUMAN" 6 1196.5223 0.05 77382 6731 2 1196.520358 599.2684 "Stress-70 protein, mitochondrial OS=Homo sapiens OX=9606 GN=HSPA9 PE=1 SV=2" 4.03 1652.3 - 183275 - - - -1.6247 - 1.386 0.197 - 150.6 1 2 0 -0.0019 10 0 0 0 4.06E+05 8.25E+06 - - - 1.4066 0.9997 221125_WJC_METTL3_EV_vs_WT_F06.06735.06735.2 0.00609 16-Sep R.QVDQLTNDK.A "sp|P08670|VIME_HUMAN,tr|B0YJC4|B0YJC4_HUMAN" 2 1059.5197 1.78 77384 6735 2 1059.520696 530.7671 Vimentin OS=Homo sapiens OX=9606 GN=VIM PE=1 SV=4 4.21 1652.8 - 1.16E+07 - - - 0.9844 - 1.725 0.472 - 376.7 1 2 0 0.001 9 0 0 0 3.00E+09 1.68E+09 - - - 4.1042 0.9962 221125_WJC_METTL3_EV_vs_WT_F06.06736.06736.2 0.0455 16-Dec R.LRSEIDNVK.K sp|P04264|K2C1_HUMAN 1 1072.5877 6859.35 77385 6736 2 1072.588601 537.3011 "Keratin, type II cytoskeletal 1 OS=Homo sapiens OX=9606 GN=KRT1 PE=1 SV=6" 6.07 1652.9 - 4.48E+06 - - - 0.8652 - 2.154 0.327 - 592.9 1 2 1 0.0009 9 0 0 0 2.43E+09 3.54E+05 - - - 3.6758 0.9976 221125_WJC_METTL3_EV_vs_WT_F06.06738.06738.2 0.00519 12-Sep K.R[166.11]VDFSAR[166.11].T "sp|P24928|RPB1_HUMAN,tr|A0A6Q8PGB0|A0A6Q8PGB0_HUMAN" 2 869.4622 0.68 77387 6738 2 869.461951 435.7384 DNA-directed RNA polymerase II subunit RPB1 OS=Homo sapiens OX=9606 GN=POLR2A PE=1 SV=2 9.6 1653.1 - 1.12E+06 - - - -0.3324 - 1.669 0.133 - 264.1 1 2 0 -0.0003 7 0 0 0 2.76E+07 4.04E+07 - - - 1.6463 0.9966 221125_WJC_METTL3_EV_vs_WT_F06.06739.06739.3 2.40E-05 13/40 T.SAGIMDHEEAR.R sp|P62244|RS15A_HUMAN 1 1214.535 0.74 77388 6739 3 1214.534872 405.8523 40S ribosomal protein S15a OS=Homo sapiens OX=9606 GN=RPS15A PE=1 SV=2 4.65 1653.1 - 899030 - - - -0.093 - 2.556 0.467 - 255 1 1 0 -0.0001 11 0 0 0 2.81E+07 3.80E+07 - - - 6.4125 0.9913 221125_WJC_METTL3_EV_vs_WT_F06.06747.06747.2 7.00E-06 20-Sep T.SAGIMDHEEAR.R sp|P62244|RS15A_HUMAN 1 1214.535 0.82 77394 6747 2 1214.536187 608.2748 40S ribosomal protein S15a OS=Homo sapiens OX=9606 GN=RPS15A PE=1 SV=2 4.65 1654.2 - 232346 - - - 0.9897 - 2.072 0.542 - 344.7 1 1 0 0.0012 11 0 0 0 4.80E+06 5.85E+06 - - - 5.0146 0.9981 221125_WJC_METTL3_EV_vs_WT_F06.06753.06753.3 7.10E-06 15/40 T.SAGIMDHEEAR[166.11].R sp|P62244|RS15A_HUMAN 1 1224.5433 0.74 77398 6753 3 1224.543798 409.1884 40S ribosomal protein S15a OS=Homo sapiens OX=9606 GN=RPS15A PE=1 SV=2 4.65 1654.9 - 1.69E+06 - - - 0.4434 - 2.706 0.524 - 366.7 1 1 0 0.0005 11 0 0 0 2.86E+07 3.87E+07 - - - 7.2099 0.9968 221125_WJC_METTL3_EV_vs_WT_F06.06754.06754.3 0.0399 Nov-44 K.TLEEQGVAHNVK.A "sp|Q9Y5A7|NUB1_HUMAN,tr|H3BM74|H3BM74_HUMAN,tr|C9JRT6|C9JRT6_HUMAN,tr|H3BM14|H3BM14_HUMAN,tr|F8WDB6|F8WDB6_HUMAN" 5 1323.6783 1.81 77399 6754 3 1323.678416 442.2334 NEDD8 ultimate buster 1 OS=Homo sapiens OX=9606 GN=NUB1 PE=1 SV=2 5.37 1654.9 - 866017 - - - 0.1035 - 1.456 0.264 - 103.4 1 2 0 0.0001 12 0 0 0 2.98E+07 1.64E+07 - - - 2.5247 0.9968 221125_WJC_METTL3_EV_vs_WT_F06.06756.06756.2 0.0449 16-Aug K.DDTDDEIAK.Y "sp|P27824|CALX_HUMAN,tr|A0A7P0T937|A0A7P0T937_HUMAN,tr|A0A7P0T840|A0A7P0T840_HUMAN,tr|A0A7P0Z4H2|A0A7P0Z4H2_HUMAN,tr|A0A7P0TB65|A0A7P0TB65_HUMAN,tr|A0A7P0TAN9|A0A7P0TAN9_HUMAN,tr|A0A7P0TAE9|A0A7P0TAE9_HUMAN,tr|A0A7P0T8N1|A0A7P0T8N1_HUMAN,tr|A0A7P0T8G1|A0A7P0T8G1_HUMAN,tr|A0A7P0Z4D6|A0A7P0Z4D6_HUMAN,tr|A0A7P0Z484|A0A7P0Z484_HUMAN,tr|A0A7P0TAR9|A0A7P0TAR9_HUMAN,tr|A0A7P0T9L0|A0A7P0T9L0_HUMAN,tr|D6RAQ8|D6RAQ8_HUMAN,tr|D6RAU8|D6RAU8_HUMAN" 15 1020.4247 1.31 77401 6756 2 1020.426967 511.2197 Calnexin OS=Homo sapiens OX=9606 GN=CANX PE=1 SV=2 3.71 1655.1 - 506598 - - - 2.1736 - 1.538 0.256 - 243.1 1 2 0 0.0022 9 0 0 0 7.36E+07 5.60E+07 - - - 2.1765 0.8674 221125_WJC_METTL3_EV_vs_WT_F06.06760.06760.2 0.439 14-Aug L.RSEIDNVK.K sp|P04264|K2C1_HUMAN 1 959.5036 1.11 77403 6760 2 959.502789 480.7591 "Keratin, type II cytoskeletal 1 OS=Homo sapiens OX=9606 GN=KRT1 PE=1 SV=6" 6.07 1655.6 - 920268 - - - -0.8546 - 1.532 0.186 - 233 1 1 0 -0.0008 8 0 0 0 6.76E+07 6.11E+07 - - - 1.7011 0.9999 221125_WJC_METTL3_EV_vs_WT_F06.06761.06761.3 7.41E-06 Nov-36 R.SHEGETAYIR.V "sp|Q07955|SRSF1_HUMAN,tr|J3KTL2|J3KTL2_HUMAN,tr|J3KSR8|J3KSR8_HUMAN" 3 1161.5415 1.03 77404 6761 3 1161.542967 388.1878 Serine\arginine-rich splicing factor 1 OS=Homo sapiens OX=9606 GN=SRSF1 PE=1 SV=2 5.38 1655.7 - 2.87E+06 - - - 1.3052 - 1.971 0.425 - 225.5 1 2 0 0.0015 10 0 0 0 6.09E+07 5.90E+07 - - - 5.2595 0.9992 221125_WJC_METTL3_EV_vs_WT_F06.06763.06763.2 0.16 16-Aug K.DDTDDEIAK[136.11].Y "sp|P27824|CALX_HUMAN,tr|A0A7P0T937|A0A7P0T937_HUMAN,tr|A0A7P0T840|A0A7P0T840_HUMAN,tr|A0A7P0Z4H2|A0A7P0Z4H2_HUMAN,tr|A0A7P0TB65|A0A7P0TB65_HUMAN,tr|A0A7P0TAN9|A0A7P0TAN9_HUMAN,tr|A0A7P0TAE9|A0A7P0TAE9_HUMAN,tr|A0A7P0T8N1|A0A7P0T8N1_HUMAN,tr|A0A7P0T8G1|A0A7P0T8G1_HUMAN,tr|A0A7P0Z4D6|A0A7P0Z4D6_HUMAN,tr|A0A7P0Z484|A0A7P0Z484_HUMAN,tr|A0A7P0TAR9|A0A7P0TAR9_HUMAN,tr|A0A7P0T9L0|A0A7P0T9L0_HUMAN,tr|D6RAQ8|D6RAQ8_HUMAN,tr|D6RAU8|D6RAU8_HUMAN" 15 1028.4389 1.39 77406 6763 2 1028.439671 515.2268 Calnexin OS=Homo sapiens OX=9606 GN=CANX PE=1 SV=2 3.71 1655.9 - 473060 - - - 0.702 - 1.679 0.295 - 306.3 1 2 0 0.0007 9 0 0 0 7.27E+07 5.22E+07 - - - 2.7188 0.9796 221125_WJC_METTL3_EV_vs_WT_F06.06764.06764.2 0.714 14-Jun K.KIEEVVER.A sp|P30837|AL1B1_HUMAN 1 1000.5553 13.01 77407 6764 2 1000.557773 501.2849 "Aldehyde dehydrogenase X, mitochondrial OS=Homo sapiens OX=9606 GN=ALDH1B1 PE=1 SV=3" 4.79 1656 - 469917 - - - 2.4616 - 1.51 0.103 - 149.7 2 2 0 0.0025 8 0 0 0 9.78E+07 7.52E+06 - - - 0.9094 0.9633 221125_WJC_METTL3_EV_vs_WT_F06.06770.06770.2 1.02 12-Jun R.QDDILK[136.11]R[166.11].L sp|Q13155|AIMP2_HUMAN 1 904.5097 1.23 77411 6770 2 904.510144 453.2621 Aminoacyl tRNA synthase complex-interacting multifunctional protein 2 OS=Homo sapiens OX=9606 GN=AIMP2 PE=1 SV=2 5.96 1656.6 - 1.96E+06 - - - 0.4898 - 1.166 0.039 - 109.3 1 2 0 0.0004 7 0 0 0 5.00E+07 4.05E+07 - - - -0.1845 0.9993 221125_WJC_METTL3_EV_vs_WT_F06.06772.06772.3 0.0194 Oct-36 K.KDVDAAYMNK.V "sp|P48668|K2C6C_HUMAN,sp|P04259|K2C6B_HUMAN,sp|P13647|K2C5_HUMAN,sp|Q14CN4|K2C72_HUMAN,sp|O95678|K2C75_HUMAN,sp|P02538|K2C6A_HUMAN,tr|F8W0C6|F8W0C6_HUMAN,tr|H0YIN9|H0YIN9_HUMAN" 8 1153.5438 49.48 77413 6772 3 1153.544252 385.5219 "Keratin, type II cytoskeletal 6C OS=Homo sapiens OX=9606 GN=KRT6C PE=1 SV=3" 5.96 1656.7 - 1.68E+06 - - - 0.4274 - 1.516 0.338 - 116.2 1 2 0 0.0005 10 0 0 0 6.58E+07 1.33E+06 - - - 3.5233 0.9997 221125_WJC_METTL3_EV_vs_WT_F06.06773.06773.2 2.82E-05 18-Jul R.SHEGETAYIR.V "sp|Q07955|SRSF1_HUMAN,tr|J3KTL2|J3KTL2_HUMAN,tr|J3KSR8|J3KSR8_HUMAN" 3 1161.5415 1.04 77414 6773 2 1161.542593 581.778 Serine\arginine-rich splicing factor 1 OS=Homo sapiens OX=9606 GN=SRSF1 PE=1 SV=2 5.38 1656.9 - 962803 - - - 0.9832 - 1.644 0.485 - 164.8 1 2 0 0.0011 10 0 0 0 2.10E+07 2.02E+07 - - - 4.0105 0.9961 221125_WJC_METTL3_EV_vs_WT_F06.06775.06775.2 0.334 14-Nov R.R[166.11]AEVDLER[166.11].V "sp|Q9P0U4|CXXC1_HUMAN,sp|P36959|GMPR1_HUMAN,tr|A0A669KB29|A0A669KB29_HUMAN" 3 1006.531 0.58 77416 6775 2 1006.528611 504.2728 CXXC-type zinc finger protein 1 OS=Homo sapiens OX=9606 GN=CXXC1 PE=1 SV=2 4.68 1657.1 - 700999 - - - -2.4212 - 1.743 0.191 - 364.1 1 2 0 -0.0024 8 0 0 0 1.02E+07 1.75E+07 - - - 2.1266 0.9998 221125_WJC_METTL3_EV_vs_WT_F06.06776.06776.2 0.00114 14-Sep R.TYDIHDPK[136.11].S sp|Q5SWX8|ODR4_HUMAN 1 995.4804 1.23 77417 6776 2 995.48033 498.7475 Protein odr-4 homolog OS=Homo sapiens OX=9606 GN=ODR4 PE=1 SV=1 5.18 1657.2 - 494210 - - - -0.0311 - 1.803 0.483 - 212.3 1 2 0 0 8 0 0 0 3.04E+07 2.48E+07 - - - 4.3862 0.9999 221125_WJC_METTL3_EV_vs_WT_F06.06781.06781.3 7.95E-07 Oct-36 R.SHEGETAYIR[166.11].V "sp|Q07955|SRSF1_HUMAN,tr|J3KTL2|J3KTL2_HUMAN,tr|J3KSR8|J3KSR8_HUMAN" 3 1171.5497 1.06 77420 6781 3 1171.549719 391.5239 Serine\arginine-rich splicing factor 1 OS=Homo sapiens OX=9606 GN=SRSF1 PE=1 SV=2 5.38 1657.8 - 2.23E+06 - - - -0.0017 - 2.178 0.401 - 245.5 1 2 0 0 10 0 0 0 6.35E+07 5.97E+07 - - - 5.284 1 221125_WJC_METTL3_EV_vs_WT_F06.06782.06782.3 0.000157 Dec-36 R.YSPVHGSQLR.R sp|Q86XL3|ANKL2_HUMAN 1 1142.5833 2 77421 6782 3 1142.582573 381.8684 Ankyrin repeat and LEM domain-containing protein 2 OS=Homo sapiens OX=9606 GN=ANKLE2 PE=1 SV=4 8.75 1657.9 - 1.95E+06 - - - -0.5978 - 2.657 0.42 - 191.3 1 2 0 -0.0007 10 0 0 0 5.79E+07 2.89E+07 - - - 6.0762 0.9965 221125_WJC_METTL3_EV_vs_WT_F06.06783.06783.2 0.566 14-Jun R.TYDIHDPK.S sp|Q5SWX8|ODR4_HUMAN 1 987.4662 1.24 77422 6783 2 987.466311 494.7404 Protein odr-4 homolog OS=Homo sapiens OX=9606 GN=ODR4 PE=1 SV=1 5.18 1657.9 - 995241 - - - 0.1519 - 1.145 0.259 - 132.8 1 2 0 0.0002 8 0 0 0 3.02E+07 2.43E+07 - - - 1.3623 0.9993 221125_WJC_METTL3_EV_vs_WT_F06.06784.06784.2 0.0154 18-Aug K.ESLETPSNGR.L "sp|P35610|SOAT1_HUMAN,tr|B1APM4|B1APM4_HUMAN" 2 1088.5098 0.51 77423 6784 2 1088.509299 545.2622 Sterol O-acyltransferase 1 OS=Homo sapiens OX=9606 GN=SOAT1 PE=1 SV=3 4.53 1658 - 962727 - - - -0.475 - 1.605 0.316 - 229.6 1 2 0 -0.0005 10 0 0 0 4.33E+07 8.54E+07 - - - 2.6954 0.9762 221125_WJC_METTL3_EV_vs_WT_F06.06790.06790.2 0.0173 20-Aug R.YLSSANPNDNR[166.11].T "sp|Q13464|ROCK1_HUMAN,tr|A0A0U1RQV4|A0A0U1RQV4_HUMAN" 2 1259.577 3.73 77427 6790 2 1259.570604 630.7958 Rho-associated protein kinase 1 OS=Homo sapiens OX=9606 GN=ROCK1 PE=1 SV=1 5.84 1658.8 - 357753 - - - -5.0763 - 1.284 0.338 - 171 1 2 0 -0.0064 11 0 0 0 8.95E+06 2.40E+06 - - - 2.2117 0.9999 221125_WJC_METTL3_EV_vs_WT_F06.06791.06791.2 9.37E-08 22-Dec K.NGGGVGGGELDK.K sp|Q9H7S9|ZN703_HUMAN 1 1058.4993 1.58 77428 6791 2 1058.499645 530.2569 Zinc finger protein 703 OS=Homo sapiens OX=9606 GN=ZNF703 PE=1 SV=1 4.37 1658.9 - 1.89E+06 - - - 0.3713 - 2.712 0.472 - 529.3 1 2 0 0.0004 12 0 0 0 7.16E+07 4.53E+07 - - - 5.1522 0.941 221125_WJC_METTL3_EV_vs_WT_F06.06792.06792.3 3.19 Aug-36 R.YNPYTTR[166.11]PNR[166.11].R "sp|Q9UBU9|NXF1_HUMAN,tr|E9PMV7|E9PMV7_HUMAN,tr|E9PLA7|E9PLA7_HUMAN,tr|E9PIN3|E9PIN3_HUMAN" 4 1300.6427 1.11 77429 6792 3 1300.643285 434.5549 Nuclear RNA export factor 1 OS=Homo sapiens OX=9606 GN=NXF1 PE=1 SV=1 9.99 1659 - 1.34E+06 - - - 0.4313 - 1.389 0.113 - 90.5 1 2 0 0.0006 10 0 0 0 7.87E+07 7.06E+07 - - - 0.7593 0.9998 221125_WJC_METTL3_EV_vs_WT_F06.06793.06793.2 0.00783 16-Oct R.HMQNSEIIR[166.11].K "sp|Q8N3U4|STAG2_HUMAN,tr|B1AMT1|B1AMT1_HUMAN,tr|B1AMT4|B1AMT4_HUMAN,tr|B1AMT3|B1AMT3_HUMAN,tr|B1AMT2|B1AMT2_HUMAN" 5 1136.5636 1.75 77430 6793 2 1136.56272 569.2891 Cohesin subunit SA-2 OS=Homo sapiens OX=9606 GN=STAG2 PE=1 SV=3 6.75 1659.1 - 724049 - - - -0.7716 - 1.655 0.469 - 287.8 1 2 0 -0.0009 9 0 0 0 3.34E+07 1.91E+07 - - - 3.9623 0.964 221125_WJC_METTL3_EV_vs_WT_F06.06794.06794.2 0.0623 18-Jul K.VYEGER[166.11]PLTK[136.11].D "sp|P11021|BIP_HUMAN,tr|A0A7P0TAI0|A0A7P0TAI0_HUMAN" 2 1208.652 0.53 77431 6794 2 1208.647796 605.3333 Endoplasmic reticulum chaperone BiP OS=Homo sapiens OX=9606 GN=HSPA5 PE=1 SV=2 6.11 1659.2 - 154079 - - - -3.4849 - 1.184 0.201 - 138.5 1 2 0 -0.0042 10 0 0 0 1.16E+07 2.21E+07 - - - 0.9957 0.9938 221125_WJC_METTL3_EV_vs_WT_F06.06797.06797.2 6.12E-05 18-Nov K.KDVDAAYMNK.V "sp|P48668|K2C6C_HUMAN,sp|P04259|K2C6B_HUMAN,sp|P13647|K2C5_HUMAN,sp|Q14CN4|K2C72_HUMAN,sp|O95678|K2C75_HUMAN,sp|P02538|K2C6A_HUMAN,tr|F8W0C6|F8W0C6_HUMAN,tr|H0YIN9|H0YIN9_HUMAN" 8 1153.5438 144.51 77432 6797 2 1153.53608 577.7792 "Keratin, type II cytoskeletal 6C OS=Homo sapiens OX=9606 GN=KRT6C PE=1 SV=3" 5.96 1659.6 - 1.16E+06 - - - -6.6569 - 2.376 0.501 - 359.1 1 2 0 -0.0077 10 0 0 0 2.66E+07 1.84E+05 - - - 5.1546 0.9937 221125_WJC_METTL3_EV_vs_WT_F06.06803.06803.3 0.155 Aug-36 R.YNPYTTRPNR.R "sp|Q9UBU9|NXF1_HUMAN,tr|E9PMV7|E9PMV7_HUMAN,tr|E9PLA7|E9PLA7_HUMAN,tr|E9PIN3|E9PIN3_HUMAN" 4 1280.6262 1.09 77436 6803 3 1280.625361 427.8827 Nuclear RNA export factor 1 OS=Homo sapiens OX=9606 GN=NXF1 PE=1 SV=1 9.99 1660.2 - 1.47E+06 - - - -0.6427 - 1.434 0.224 - 83.9 1 2 0 -0.0008 10 0 0 0 7.67E+07 7.05E+07 - - - 2.0899 0.9997 221125_WJC_METTL3_EV_vs_WT_F06.06804.06804.3 0.0223 Nov-40 R.NPPPNSDPNLR.R sp|Q96I24|FUBP3_HUMAN 1 1219.5945 2.03 77437 6804 3 1219.593657 407.5388 Far upstream element-binding protein 3 OS=Homo sapiens OX=9606 GN=FUBP3 PE=1 SV=2 5.84 1660.3 - 1.01E+06 - - - -0.7314 - 2.014 0.338 - 202.7 1 2 0 -0.0009 11 0 0 0 2.72E+07 1.34E+07 - - - 4.297 0.9995 221125_WJC_METTL3_EV_vs_WT_F06.06808.06808.2 1.01E-07 16-Oct K.GDDLQAIKK.E "sp|P07910|HNRPC_HUMAN,tr|B4DY08|B4DY08_HUMAN,tr|G3V5V7|G3V5V7_HUMAN,tr|B2R5W2|B2R5W2_HUMAN,tr|G3V4C1|G3V4C1_HUMAN,tr|G3V576|G3V576_HUMAN,tr|G3V2D6|G3V2D6_HUMAN,tr|G3V4W0|G3V4W0_HUMAN,tr|G3V2Q1|G3V2Q1_HUMAN" 9 986.5397 1.39 77439 6808 2 986.542669 494.2771 Heterogeneous nuclear ribonucleoproteins C1\C2 OS=Homo sapiens OX=9606 GN=HNRNPC PE=1 SV=4 5.96 1660.9 - 2.01E+06 - - - 3.0501 - 2.151 0.542 - 469.9 1 2 0 0.003 9 0 0 0 1.47E+08 1.06E+08 - - - 5.2592 0.9999 221125_WJC_METTL3_EV_vs_WT_F06.06809.06809.3 0.000367 Nov-36 K.VVSTHEQVLR.T sp|P02533|K1C14_HUMAN 1 1166.6408 8.6 77440 6809 3 1166.640358 389.8875 "Keratin, type I cytoskeletal 14 OS=Homo sapiens OX=9606 GN=KRT14 PE=1 SV=4" 6.72 1660.9 - 2.09E+06 - - - -0.354 - 2.299 0.383 - 284.6 1 2 0 -0.0004 10 0 0 0 1.60E+08 1.86E+07 - - - 5.2411 0.9993 221125_WJC_METTL3_EV_vs_WT_F06.06815.06815.2 0.0545 16-Jul K.LHPDVPTDK.N "sp|Q6W2J9|BCOR_HUMAN,tr|H7BZ37|H7BZ37_HUMAN,tr|A1A564|A1A564_HUMAN,tr|H7C2V9|H7C2V9_HUMAN,tr|H7BYY2|H7BYY2_HUMAN,tr|H7C231|H7C231_HUMAN" 6 1020.524 0.77 77444 6815 2 1020.524021 511.2693 BCL-6 corepressor OS=Homo sapiens OX=9606 GN=BCOR PE=1 SV=1 5.21 1661.6 - 3.94E+06 - - - 0.0108 - 1.436 0.345 - 180.2 1 2 0 0 9 0 0 0 9.50E+07 1.24E+08 - - - 2.6361 0.9988 221125_WJC_METTL3_EV_vs_WT_F06.06819.06819.2 0.00821 16-Jul K.LHPDVPTDK[136.11].N "sp|Q6W2J9|BCOR_HUMAN,tr|H7BZ37|H7BZ37_HUMAN,tr|A1A564|A1A564_HUMAN,tr|H7C2V9|H7C2V9_HUMAN,tr|H7BYY2|H7BYY2_HUMAN,tr|H7C231|H7C231_HUMAN" 6 1028.5382 1.71 77446 6819 2 1028.53847 515.2764 BCL-6 corepressor OS=Homo sapiens OX=9606 GN=BCOR PE=1 SV=1 5.21 1662.2 - 2.67E+06 - - - 0.2528 - 1.426 0.294 - 214.3 1 2 0 0.0003 9 0 0 0 9.07E+07 5.30E+07 - - - 2.2391 0.9995 221125_WJC_METTL3_EV_vs_WT_F06.06821.06821.2 0.000119 18-Sep K.VVSTHEQVLR.T sp|P02533|K1C14_HUMAN 1 1166.6408 14.05 77448 6821 2 1166.640865 584.3277 "Keratin, type I cytoskeletal 14 OS=Homo sapiens OX=9606 GN=KRT14 PE=1 SV=4" 6.72 1662.4 - 832898 - - - 0.0806 - 1.81 0.326 - 321.8 1 2 0 0.0001 10 0 0 0 2.51E+07 1.78E+06 - - - 3.105 0.9994 221125_WJC_METTL3_EV_vs_WT_F06.06826.06826.3 0.000272 Nov-36 K.TGDEEMLK[136.11]DK[136.11].G "sp|Q96EI5|TCAL4_HUMAN,tr|D6RD44|D6RD44_HUMAN,tr|D6RCE9|D6RCE9_HUMAN,tr|A2RQR6|A2RQR6_HUMAN,tr|D6RIH3|D6RIH3_HUMAN" 5 1180.5617 1.65 77451 6826 3 1180.561861 394.5278 Transcription elongation factor A protein-like 4 OS=Homo sapiens OX=9606 GN=TCEAL4 PE=1 SV=2 4.32 1663 - 533087 - - - 0.1753 - 2.152 0.379 - 182 1 2 1 0.0002 10 0 0 0 2.24E+07 1.35E+07 - - - 5.0036 0.8584 221125_WJC_METTL3_EV_vs_WT_F06.06832.06832.2 4.1 12-Aug D.DLQAIKK.E "sp|P07910|HNRPC_HUMAN,tr|B4DY08|B4DY08_HUMAN,tr|G3V5V7|G3V5V7_HUMAN,tr|B2R5W2|B2R5W2_HUMAN,tr|G3V4C1|G3V4C1_HUMAN,tr|G3V576|G3V576_HUMAN,tr|G3V2D6|G3V2D6_HUMAN,tr|G3V4W0|G3V4W0_HUMAN,tr|G3V2Q1|G3V2Q1_HUMAN" 9 814.4913 1.88 77455 6832 2 814.491179 408.2529 Heterogeneous nuclear ribonucleoproteins C1\C2 OS=Homo sapiens OX=9606 GN=HNRNPC PE=1 SV=4 8.59 1663.8 - 3.63E+06 - - - -0.0909 - 1.581 0.142 - 236.4 1 1 0 -0.0001 7 0 0 0 6.35E+07 3.37E+07 - - - 1.5412 0.9997 221125_WJC_METTL3_EV_vs_WT_F06.06835.06835.2 0.00113 16-Aug K.GSSNSYAIK[136.11].K "sp|P46782|RS5_HUMAN,tr|M0QZN2|M0QZN2_HUMAN,tr|M0R0F0|M0R0F0_HUMAN,tr|M0R0R2|M0R0R2_HUMAN" 4 933.4647 0.97 77458 6835 2 933.464174 467.7396 40S ribosomal protein S5 OS=Homo sapiens OX=9606 GN=RPS5 PE=1 SV=4 8.59 1664 - 1.90E+06 - - - -0.5753 - 1.789 0.389 - 276.3 1 2 0 -0.0005 9 0 0 0 4.57E+08 4.70E+08 - - - 3.5967 0.9766 221125_WJC_METTL3_EV_vs_WT_F06.06837.06837.2 0.00153 16-Sep V.YEGER[166.11]PLTK[136.11].D "sp|P11021|BIP_HUMAN,tr|A0A7P0TAI0|A0A7P0TAI0_HUMAN" 2 1109.5836 0.73 77460 6837 2 1109.581873 555.7991 Endoplasmic reticulum chaperone BiP OS=Homo sapiens OX=9606 GN=HSPA5 PE=1 SV=2 6.14 1664.2 - 362119 - - - -1.551 - 1.69 0.439 - 170.8 1 1 0 -0.0017 9 0 0 0 4.52E+06 6.22E+06 - - - 3.801 0.9967 221125_WJC_METTL3_EV_vs_WT_F06.06843.06843.3 0.213 Sep-44 K.EAVGGQAEDHLK.L "sp|Q8IWC1|MA7D3_HUMAN,tr|A0A0A0MRP0|A0A0A0MRP0_HUMAN" 2 1252.6048 0.49 77465 6843 3 1252.60416 418.5422 MAP7 domain-containing protein 3 OS=Homo sapiens OX=9606 GN=MAP7D3 PE=1 SV=2 4.65 1665 - 433646 - - - -0.495 - 1.578 0.241 - 82.5 1 2 0 -0.0006 12 0 0 0 8.80E+06 1.81E+07 - - - 2.4911 1 221125_WJC_METTL3_EV_vs_WT_F06.06846.06846.2 2.35E-08 13/24 R.VVTSEDQVQEGTK.V "sp|Q8WWK9|CKAP2_HUMAN,tr|C9J7Y4|C9J7Y4_HUMAN" 2 1418.6889 0.81 77467 6846 2 1418.689402 710.3517 Cytoskeleton-associated protein 2 OS=Homo sapiens OX=9606 GN=CKAP2 PE=1 SV=1 4.14 1665.3 - 614951 - - - 0.3517 - 2.628 0.639 - 460.2 1 2 0 0.0005 13 0 0 0 5.10E+07 6.26E+07 - - - 6.2403 0.9996 221125_WJC_METTL3_EV_vs_WT_F06.06848.06848.2 0.118 14-Oct R.K[136.11]ADIDLTK[136.11].R sp|P62269|RS18_HUMAN 1 918.5357 1.01 77469 6848 2 918.535824 460.2751 40S ribosomal protein S18 OS=Homo sapiens OX=9606 GN=RPS18 PE=1 SV=3 5.96 1665.4 - 1.91E+06 - - - 0.1383 - 1.872 0.335 - 341.3 1 2 0 0.0001 8 0 0 0 1.93E+09 1.92E+09 - - - 3.4063 0.9911 221125_WJC_METTL3_EV_vs_WT_F06.06854.06854.2 0.016 14-Jul K.SK[136.11]FDEMAK[136.11].A "sp|O15347|HMGB3_HUMAN,tr|E9PES6|E9PES6_HUMAN,tr|E7EQU1|E7EQU1_HUMAN,tr|E7ES08|E7ES08_HUMAN" 4 970.4765 0.19 77473 6854 2 970.476591 486.2455 High mobility group protein B3 OS=Homo sapiens OX=9606 GN=HMGB3 PE=1 SV=4 5.79 1666.3 - 3.64E+06 - - - 0.1267 - 1.529 0.305 - 127.1 1 2 1 0.0001 8 0 0 0 1.67E+07 8.63E+07 - - - 2.5743 0.9999 221125_WJC_METTL3_EV_vs_WT_F06.06855.06855.2 6.06E-05 13/24 R.VVTSEDQVQEGTK[136.11].V "sp|Q8WWK9|CKAP2_HUMAN,tr|C9J7Y4|C9J7Y4_HUMAN" 2 1426.7031 0.81 77474 6855 2 1426.702497 714.3588 Cytoskeleton-associated protein 2 OS=Homo sapiens OX=9606 GN=CKAP2 PE=1 SV=1 4.14 1666.3 - 1.20E+06 - - - -0.4248 - 2.583 0.543 - 494.1 1 2 0 -0.0006 13 0 0 0 5.10E+07 6.26E+07 - - - 5.4869 0.9999 221125_WJC_METTL3_EV_vs_WT_F06.06856.06856.2 1.51E-05 16-Dec K.KDDAITAYK.K "sp|Q9BY77|PDIP3_HUMAN,tr|F6VRR5|F6VRR5_HUMAN" 2 1023.5237 1.52 77475 6856 2 1023.524318 512.7691 Polymerase delta-interacting protein 3 OS=Homo sapiens OX=9606 GN=POLDIP3 PE=1 SV=2 5.96 1666.4 - 3.07E+06 - - - 0.6272 - 2.561 0.412 - 438.4 1 2 0 0.0006 9 0 0 0 9.40E+08 6.18E+08 - - - 4.8045 1 221125_WJC_METTL3_EV_vs_WT_F06.06857.06857.2 1.96E-06 15/16 K.K[136.11]DDAITAYK[136.11].K "sp|Q9BY77|PDIP3_HUMAN,tr|F6VRR5|F6VRR5_HUMAN" 2 1039.5521 1.52 77476 6857 2 1039.552377 520.7833 Polymerase delta-interacting protein 3 OS=Homo sapiens OX=9606 GN=POLDIP3 PE=1 SV=2 5.96 1666.5 - 2.72E+06 - - - 0.2895 - 3.341 0.502 - 712.7 1 2 0 0.0003 9 0 0 0 9.39E+08 6.19E+08 - - - 6.2385 0.9996 221125_WJC_METTL3_EV_vs_WT_F06.06859.06859.3 0.000656 Dec-44 R.R[166.11]IVAVTGAEAQK[136.11].A "sp|P49588|SYAC_HUMAN,tr|A0A6Q8PGR9|A0A6Q8PGR9_HUMAN,tr|A0A6Q8PFY2|A0A6Q8PFY2_HUMAN,tr|A0A6Q8PFK3|A0A6Q8PFK3_HUMAN,tr|H3BPK7|H3BPK7_HUMAN,tr|A0A6Q8PGB5|A0A6Q8PGB5_HUMAN,tr|A0A6Q8PGE8|A0A6Q8PGE8_HUMAN,tr|A0A6Q8PF33|A0A6Q8PF33_HUMAN,tr|A0A6Q8PGN5|A0A6Q8PGN5_HUMAN" 9 1259.7317 1.26 77478 6859 3 1259.732113 420.9178 "Alanine--tRNA ligase, cytoplasmic OS=Homo sapiens OX=9606 GN=AARS1 PE=1 SV=2" 8.75 1666.7 - 432242 - - - 0.3636 - 1.95 0.328 - 209.6 1 2 0 0.0005 12 0 0 0 1.00E+07 7.96E+06 - - - 4.0479 0.994 221125_WJC_METTL3_EV_vs_WT_F06.06863.06863.2 0.00597 22-Oct R.IKENGAAALDGR.L "sp|P57105|SYJ2B_HUMAN,tr|A0A087X1F5|A0A087X1F5_HUMAN,tr|A0A087WYV9|A0A087WYV9_HUMAN" 3 1213.6415 1.63 77482 6863 2 1213.640005 607.828 Synaptojanin-2-binding protein OS=Homo sapiens OX=9606 GN=SYNJ2BP PE=1 SV=2 6.07 1667.2 - 198917 - - - -1.231 - 1.939 0.334 - 195.4 1 2 1 -0.0015 12 0 0 0 4.51E+07 2.77E+07 - - - 3.2497 1 221125_WJC_METTL3_EV_vs_WT_F06.06864.06864.2 1.23E-07 18-Sep R.YDSYESC[160.03]DSR[166.11].A "sp|Q9ULX6|AKP8L_HUMAN,tr|M0QYT7|M0QYT7_HUMAN,tr|A0A7P0T9N5|A0A7P0T9N5_HUMAN,tr|A0A7P0TAD3|A0A7P0TAD3_HUMAN,tr|V9GZ50|V9GZ50_HUMAN,tr|A0A7P0TBP0|A0A7P0TBP0_HUMAN,tr|M0R1Y5|M0R1Y5_HUMAN,tr|A0A7P0TAJ5|A0A7P0TAJ5_HUMAN,tr|A0A7P0TAE3|A0A7P0TAE3_HUMAN,tr|M0R010|M0R010_HUMAN,tr|A0A7P0T847|A0A7P0T847_HUMAN" 11 1290.4698 1.5 77483 6864 2 1290.467291 646.2422 A-kinase anchor protein 8-like OS=Homo sapiens OX=9606 GN=AKAP8L PE=1 SV=4 4.03 1667.4 - 110949 - - - -1.9567 - 2.056 0.719 - 262.3 1 2 0 -0.0025 10 0 0 0 5.29E+06 3.53E+06 - - - 6.3626 0.9998 221125_WJC_METTL3_EV_vs_WT_F06.06868.06868.2 0.0245 14-Nov R.KADIDLTK.R sp|P62269|RS18_HUMAN 1 902.5073 1.01 77485 6868 2 902.507871 452.2609 40S ribosomal protein S18 OS=Homo sapiens OX=9606 GN=RPS18 PE=1 SV=3 5.96 1667.8 - 9.15E+06 - - - 0.636 - 2.329 0.387 - 416.5 1 2 0 0.0006 8 0 0 0 1.93E+09 1.92E+09 - - - 4.449 0.9998 221125_WJC_METTL3_EV_vs_WT_F06.06869.06869.2 0.00989 16-Sep R.SQESGYYDR.M "sp|P43243|MATR3_HUMAN,tr|A8MXP9|A8MXP9_HUMAN,tr|D6R991|D6R991_HUMAN,tr|A0A0R4J2E8|A0A0R4J2E8_HUMAN,tr|D6REM6|D6REM6_HUMAN" 5 1103.452 1.23 77486 6869 2 1103.451648 552.7333 Matrin-3 OS=Homo sapiens OX=9606 GN=MATR3 PE=1 SV=2 4.37 1667.9 - 2.80E+06 - - - -0.2891 - 1.844 0.437 - 408.6 1 2 0 -0.0003 9 0 0 0 1.15E+10 9.33E+09 - - - 4.0389 1 221125_WJC_METTL3_EV_vs_WT_F06.06870.06870.2 4.04E-09 20-Sep R.SGC[160.03]C[160.03]DDSALAR.S sp|Q9P1Y5|CAMP3_HUMAN 1 1210.4707 1.69 77487 6870 2 1210.471107 606.2426 Calmodulin-regulated spectrin-associated protein 3 OS=Homo sapiens OX=9606 GN=CAMSAP3 PE=1 SV=2 4.21 1668 - 1.08E+06 - - - 0.3602 - 2.059 0.692 - 318 1 2 0 0.0004 11 0 0 0 2.67E+07 1.59E+07 - - - 6.1058 0.9998 221125_WJC_METTL3_EV_vs_WT_F06.06871.06871.2 0.0029 18-Sep K.GQAVDYEGSR[166.11].T "sp|P13667|PDIA4_HUMAN,tr|A0A499FI48|A0A499FI48_HUMAN" 2 1090.4919 0.95 77488 6871 2 1090.490658 546.2532 Protein disulfide-isomerase A4 OS=Homo sapiens OX=9606 GN=PDIA4 PE=1 SV=2 4.37 1668.1 - 875445 - - - -1.1133 - 1.988 0.501 - 401.1 1 2 0 -0.0012 10 0 0 0 1.44E+07 1.52E+07 - - - 4.659 0.9999 221125_WJC_METTL3_EV_vs_WT_F06.06873.06873.2 1.39E-05 22-Nov R.LVSSDPEINTKK.L sp|Q9Y266|NUDC_HUMAN 1 1329.714 1.44 77490 6873 2 1329.714209 665.8643 Nuclear migration protein nudC OS=Homo sapiens OX=9606 GN=NUDC PE=1 SV=1 6.07 1668.3 - 513811 - - - 0.1602 - 1.997 0.549 - 290.9 1 2 0 0.0002 12 0 0 0 1.68E+07 1.17E+07 - - - 4.9157 0.9998 221125_WJC_METTL3_EV_vs_WT_F06.06875.06875.2 0.00742 16-Jul K.GSSNSYAIK.K "sp|P46782|RS5_HUMAN,tr|M0QZN2|M0QZN2_HUMAN,tr|M0R0F0|M0R0F0_HUMAN,tr|M0R0R2|M0R0R2_HUMAN" 4 925.4505 0.97 77491 6875 2 925.450442 463.7325 40S ribosomal protein S5 OS=Homo sapiens OX=9606 GN=RPS5 PE=1 SV=4 8.59 1668.6 - 1.59E+07 - - - -0.0746 - 1.817 0.441 - 238.2 1 2 0 -0.0001 9 0 0 0 4.57E+08 4.69E+08 - - - 4.0259 0.9997 221125_WJC_METTL3_EV_vs_WT_F06.06876.06876.2 3.15E-05 20-Oct R.EPALGPHGPSR[166.11].H "tr|K7EQG2|K7EQG2_HUMAN,tr|E9PAU2|E9PAU2_HUMAN,tr|A0A087WZ13|A0A087WZ13_HUMAN" 3 1126.5759 0.89 77492 6876 2 1126.577134 564.2952 Uncharacterized protein (Fragment) OS=Homo sapiens OX=9606 PE=1 SV=1 6.85 1668.6 - 2.46E+06 - - - 1.1167 - 1.964 0.45 - 430 1 2 0 0.0013 11 0 0 0 2.83E+08 3.18E+08 - - - 4.1903 0.9999 221125_WJC_METTL3_EV_vs_WT_F06.06877.06877.2 0.00526 16-Aug R.SQESGYYDR[166.11].M "sp|P43243|MATR3_HUMAN,tr|A8MXP9|A8MXP9_HUMAN,tr|D6R991|D6R991_HUMAN,tr|A0A0R4J2E8|A0A0R4J2E8_HUMAN,tr|D6REM6|D6REM6_HUMAN" 5 1113.4602 1.23 77493 6877 2 1113.460166 557.7374 Matrin-3 OS=Homo sapiens OX=9606 GN=MATR3 PE=1 SV=2 4.37 1668.6 - 7.05E+06 - - - -0.0638 - 1.809 0.587 - 317.1 1 2 0 -0.0001 9 0 0 0 1.15E+10 9.33E+09 - - - 5.0915 0.9902 221125_WJC_METTL3_EV_vs_WT_F06.06878.06878.3 0.00952 Dec-44 R.IKENGAAALDGR.L "sp|P57105|SYJ2B_HUMAN,tr|A0A087X1F5|A0A087X1F5_HUMAN,tr|A0A087WYV9|A0A087WYV9_HUMAN" 3 1213.6415 1.54 77494 6878 3 1213.640347 405.5544 Synaptojanin-2-binding protein OS=Homo sapiens OX=9606 GN=SYNJ2BP PE=1 SV=2 6.07 1668.7 - 4.58E+06 - - - -0.9492 - 2.305 0.173 - 218.4 1 2 1 -0.0012 12 0 0 0 1.97E+08 1.28E+08 - - - 2.7832 0.8393 221125_WJC_METTL3_EV_vs_WT_F06.06887.06887.2 1.05 14-May R.QTFITLEK.F sp|Q5UIP0|RIF1_HUMAN 1 978.5386 19.1 77501 6887 2 978.535259 490.2766 Telomere-associated protein RIF1 OS=Homo sapiens OX=9606 GN=RIF1 PE=1 SV=2 6 1669.8 - 3.63E+06 - - - -3.4112 - 1.03 0.167 - 67.2 12 2 0 -0.0033 8 0 0 0 1.66E+08 8.71E+06 - - - -0.1195 0.9992 221125_WJC_METTL3_EV_vs_WT_F06.06888.06888.2 0.0225 14-Jul K.EFNAEVHR.K "sp|P46777|RL5_HUMAN,tr|A0A2R8Y6J3|A0A2R8Y6J3_HUMAN" 2 1000.4726 1 77502 6888 2 1000.472892 501.2436 60S ribosomal protein L5 OS=Homo sapiens OX=9606 GN=RPL5 PE=1 SV=3 5.4 1669.9 - 2.25E+06 - - - 0.2489 - 1.473 0.328 - 339.3 1 2 0 0.0002 8 0 0 0 1.33E+08 1.33E+08 - - - 2.6316 0.9988 221125_WJC_METTL3_EV_vs_WT_F06.06892.06892.2 0.17 18-Sep R.TGPIKPQAIK.T "sp|Q9Y520|PRC2C_HUMAN,tr|E7EPN9|E7EPN9_HUMAN,tr|H7C5N8|H7C5N8_HUMAN,tr|A0A2R8YET2|A0A2R8YET2_HUMAN" 4 1051.639 2.75 77504 6892 2 1051.638039 526.8268 Protein PRRC2C OS=Homo sapiens OX=9606 GN=PRRC2C PE=1 SV=4 10 1670.4 - 1.62E+06 - - - -0.8948 - 1.62 0.263 - 197.1 1 2 0 -0.0009 10 0 0 0 2.50E+07 9.08E+06 - - - 2.3298 0.9997 221125_WJC_METTL3_EV_vs_WT_F06.06894.06894.2 0.000464 24-Aug R.SVQEGENPDDGVR.G "sp|P42696|RBM34_HUMAN,tr|Q5TCT4|Q5TCT4_HUMAN,tr|A2A2V2|A2A2V2_HUMAN,tr|H7C5M1|H7C5M1_HUMAN" 4 1400.6168 1.6 77505 6894 2 1400.616026 701.3157 RNA-binding protein 34 OS=Homo sapiens OX=9606 GN=RBM34 PE=1 SV=2 3.92 1670.7 - 284954 - - - -0.5533 - 1.733 0.428 - 175.3 1 2 0 -0.0008 13 0 0 0 5.23E+06 3.26E+06 - - - 3.6132 0.9553 221125_WJC_METTL3_EV_vs_WT_F06.06896.06896.2 0.00574 16-Sep P.ALGPHGPSR.H "tr|K7EQG2|K7EQG2_HUMAN,tr|E9PAU2|E9PAU2_HUMAN,tr|A0A087WZ13|A0A087WZ13_HUMAN" 3 890.4722 1.15 77507 6896 2 890.472893 446.2434 Uncharacterized protein (Fragment) OS=Homo sapiens OX=9606 PE=1 SV=1 9.8 1670.9 - 1.29E+06 - - - 0.7232 - 1.558 0.328 - 321.4 1 1 0 0.0006 9 0 0 0 9.95E+07 8.64E+07 - - - 2.7462 0.8355 221125_WJC_METTL3_EV_vs_WT_F06.06901.06901.3 42.8 Mar-40 M.GC[160.03]C[160.03]GC[160.03]GGC[160.03]GGR.C sp|A0A286YEX9|SCGRX_HUMAN 1 1156.3631 1.18 77510 6901 3 1156.363573 386.4616 Small cysteine and glycine repeat-containing protein 10 OS=Homo sapiens OX=9606 GN=SCYGR10 PE=1 SV=1 7.89 1671.5 - 6.36E+06 - - - 0.4506 - 0.679 0.242 - 11.3 1 2 0 0.0005 11 0 0 0 8.72E+08 7.41E+08 - - - 0.1381 0.994 221125_WJC_METTL3_EV_vs_WT_F06.06902.06902.2 0.000339 24-Dec L.VSGLNSSASEPAK[136.11].E "sp|Q86U44|MTA70_HUMAN,tr|F5H6D8|F5H6D8_HUMAN,tr|H0YFV6|H0YFV6_HUMAN,tr|B4DTN4|B4DTN4_HUMAN" 4 1253.6343 0.02 77511 6902 2 1253.633844 627.8244 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 5.97 1671.6 - 3.61E+06 - - - -0.3598 - 2.492 0.521 - 477.7 1 1 0 -0.0005 13 0 0 0 5.70E+06 3.66E+08 - - - 5.2324 0.9816 221125_WJC_METTL3_EV_vs_WT_F06.06906.06906.2 0.258 18-Oct R.QLTPPEGSSK[136.11].S "sp|Q99613|EIF3C_HUMAN,sp|B5ME19|EIFCL_HUMAN" 2 1050.5437 0.48 77514 6906 2 1050.540403 526.2791 Eukaryotic translation initiation factor 3 subunit C OS=Homo sapiens OX=9606 GN=EIF3C PE=1 SV=1 6 1672 - 1.21E+06 - - - -3.1279 - 1.545 0.142 - 266.4 1 2 0 -0.0033 10 0 0 0 1.41E+07 2.96E+07 - - - 1.3031 0.9989 221125_WJC_METTL3_EV_vs_WT_F06.06934.06934.2 0.0148 20-Jun R.GPPPSYGGSSR[166.11].Y "sp|Q96E39|RMXL1_HUMAN,sp|P38159|RBMX_HUMAN,tr|H3BUY5|H3BUY5_HUMAN" 3 1070.502 3.85 77529 6934 2 1070.50274 536.2583 "RNA binding motif protein, X-linked-like-1 OS=Homo sapiens OX=9606 GN=RBMXL1 PE=1 SV=1" 8.75 1675.2 - 721445 - - - 0.652 - 1.324 0.352 - 92.8 1 2 0 0.0007 11 0 0 0 8.75E+07 2.27E+07 - - - 2.3999 0.866 221125_WJC_METTL3_EV_vs_WT_F06.06954.06954.2 0.616 16-Jun K.IINYR[166.11]DDEK[136.11].S "sp|Q93009|UBP7_HUMAN,tr|H3BRA2|H3BRA2_HUMAN,tr|A0A669KBL1|A0A669KBL1_HUMAN,tr|H3BUV0|H3BUV0_HUMAN,tr|F5H2X1|F5H2X1_HUMAN,tr|H3BQD1|H3BQD1_HUMAN,tr|H3BND8|H3BND8_HUMAN,tr|H3BTM1|H3BTM1_HUMAN" 8 1182.6 2.5 77540 6954 2 1182.598379 592.3073 Ubiquitin carboxyl-terminal hydrolase 7 OS=Homo sapiens OX=9606 GN=USP7 PE=1 SV=2 4.56 1677.5 - 600437 - - - -1.347 - 1.286 0.137 - 82.8 2 2 1 -0.0016 9 0 0 0 2.85E+07 1.14E+07 - - - 0.6456 0.9993 221125_WJC_METTL3_EV_vs_WT_F06.06957.06957.2 0.00273 16-Aug R.TASQGQWGR[166.11].A "sp|Q9UBM7|DHCR7_HUMAN,tr|E9PIP9|E9PIP9_HUMAN,tr|E9PJ54|E9PJ54_HUMAN,tr|E9PRL8|E9PRL8_HUMAN,tr|E9PM00|E9PM00_HUMAN,tr|A0A804HI25|A0A804HI25_HUMAN,tr|A0A804HJQ7|A0A804HJQ7_HUMAN,tr|A0A804HJI8|A0A804HJI8_HUMAN,tr|A0A804HL56|A0A804HL56_HUMAN,tr|E9PQ71|E9PQ71_HUMAN" 10 999.4762 0.38 77541 6957 2 999.475674 500.7454 7-dehydrocholesterol reductase OS=Homo sapiens OX=9606 GN=DHCR7 PE=1 SV=1 9.41 1677.9 - 2.75E+06 - - - -0.4883 - 1.552 0.32 - 209.8 1 2 0 -0.0005 9 0 0 0 4.53E+07 1.20E+08 - - - 2.676 0.831 221125_WJC_METTL3_EV_vs_WT_F06.06959.06959.2 0.599 18-Sep A.K[136.11]EELSAALEK[136.11].A "sp|P82094|TMF1_HUMAN,tr|F8WF45|F8WF45_HUMAN" 2 1132.6311 0.44 77542 6959 2 1132.628401 567.3228 TATA element modulatory factor OS=Homo sapiens OX=9606 GN=TMF1 PE=1 SV=2 4.79 1678.1 - 1.34E+06 - - - -2.3423 - 2.071 0.152 - 402.2 1 1 0 -0.0027 10 0 0 0 1.03E+07 2.34E+07 - - - 2.195 0.9994 221125_WJC_METTL3_EV_vs_WT_F06.06964.06964.2 8.96E-08 13/14 R.HNLLQAC[160.03]K[136.11].M "sp|Q14683|SMC1A_HUMAN,tr|G8JLG1|G8JLG1_HUMAN,tr|A0A6Q8PHC3|A0A6Q8PHC3_HUMAN,tr|V9GY57|V9GY57_HUMAN" 4 990.516 0.68 77545 6964 2 990.514179 496.2653 Structural maintenance of chromosomes protein 1A OS=Homo sapiens OX=9606 GN=SMC1A PE=1 SV=2 8.23 1678.8 - 2.16E+06 - - - -1.8738 - 2.331 0.262 - 576.1 1 2 0 -0.0019 8 0 0 0 4.13E+07 6.05E+07 - - - 3.5279 0.9146 221125_WJC_METTL3_EV_vs_WT_F06.06965.06965.3 0.206 Oct-40 K.QVLDGK[136.11]EEVEK[136.11].Q "sp|P82094|TMF1_HUMAN,tr|F8WF45|F8WF45_HUMAN" 2 1288.6845 1.2 77546 6965 3 1288.684625 430.5688 TATA element modulatory factor OS=Homo sapiens OX=9606 GN=TMF1 PE=1 SV=2 4.41 1678.9 - 1.19E+06 - - - 0.0613 - 1.726 0.117 - 109.4 1 2 1 0.0001 11 0 0 0 6.32E+07 5.25E+07 - - - 1.395 0.88 221125_WJC_METTL3_EV_vs_WT_F06.06966.06966.2 1.95 12-Aug K.LRDDFEK.K "sp|Q9Y2W1|TR150_HUMAN,tr|A0A3B3ITZ9|A0A3B3ITZ9_HUMAN" 2 921.4556 2.67 77547 6966 2 921.453489 461.7351 Thyroid hormone receptor-associated protein 3 OS=Homo sapiens OX=9606 GN=THRAP3 PE=1 SV=2 4.56 1678.9 - 1.12E+07 - - - -2.2866 - 1.635 0.077 - 387.9 1 2 1 -0.0021 7 0 0 0 4.20E+08 1.57E+08 - - - 1.1669 0.9992 221125_WJC_METTL3_EV_vs_WT_F06.06967.06967.2 0.0164 20-Oct R.NPPPNSDPNLR[166.11].R sp|Q96I24|FUBP3_HUMAN 1 1229.6028 2.34 77548 6967 2 1229.602696 615.8087 Far upstream element-binding protein 3 OS=Homo sapiens OX=9606 GN=FUBP3 PE=1 SV=2 5.84 1679 - 3.18E+06 - - - -0.1 - 1.864 0.25 - 197 1 2 0 -0.0001 11 0 0 0 4.85E+08 2.07E+08 - - - 2.5721 0.9997 221125_WJC_METTL3_EV_vs_WT_F06.06968.06968.2 0.00308 14-Nov R.HNLLQAC[160.03]K.M "sp|Q14683|SMC1A_HUMAN,tr|G8JLG1|G8JLG1_HUMAN,tr|A0A6Q8PHC3|A0A6Q8PHC3_HUMAN,tr|V9GY57|V9GY57_HUMAN" 4 982.5018 0.66 77549 6968 2 982.501224 492.2582 Structural maintenance of chromosomes protein 1A OS=Homo sapiens OX=9606 GN=SMC1A PE=1 SV=2 8.23 1679.1 - 1.55E+06 - - - -0.6219 - 2.281 0.266 - 357.2 1 2 0 -0.0006 8 0 0 0 4.15E+07 6.29E+07 - - - 3.4925 0.9826 221125_WJC_METTL3_EV_vs_WT_F06.06970.06970.2 1.37 14-Aug R.TIELDGKR.L sp|P61006|RAB8A_HUMAN 1 930.5134 1.06 77551 6970 2 930.512826 466.264 Ras-related protein Rab-8A OS=Homo sapiens OX=9606 GN=RAB8A PE=1 SV=1 5.74 1679.4 - 668898 - - - -0.6652 - 1.179 0.102 - 224 1 2 0 -0.0006 8 0 0 0 2.23E+07 2.11E+07 - - - 0.2908 0.9995 221125_WJC_METTL3_EV_vs_WT_F06.06974.06974.2 0.000816 20-Sep R.NPPPNSDPNLR.R sp|Q96I24|FUBP3_HUMAN 1 1219.5945 2.35 77554 6974 2 1219.593883 610.8046 Far upstream element-binding protein 3 OS=Homo sapiens OX=9606 GN=FUBP3 PE=1 SV=2 5.84 1679.8 - 6.01E+06 - - - -0.5461 - 1.942 0.307 - 244.8 1 2 0 -0.0007 11 0 0 0 5.00E+08 2.13E+08 - - - 3.1038 0.9717 221125_WJC_METTL3_EV_vs_WT_F06.06975.06975.2 0.0497 12-Jul K.LR[166.11]DDFEK[136.11].K "sp|Q9Y2W1|TR150_HUMAN,tr|A0A3B3ITZ9|A0A3B3ITZ9_HUMAN" 2 939.4781 2.67 77555 6975 2 939.476837 470.7463 Thyroid hormone receptor-associated protein 3 OS=Homo sapiens OX=9606 GN=THRAP3 PE=1 SV=2 4.56 1679.8 - 8.25E+06 - - - -1.3082 - 1.635 0.169 - 301.4 1 2 1 -0.0012 7 0 0 0 4.20E+08 1.57E+08 - - - 1.8466 0.9869 221125_WJC_METTL3_EV_vs_WT_F06.06976.06976.3 0.0238 13/40 K.QVLDGKEEVEK.Q "sp|P82094|TMF1_HUMAN,tr|F8WF45|F8WF45_HUMAN" 2 1272.6561 1.09 77556 6976 3 1272.654734 425.226 TATA element modulatory factor OS=Homo sapiens OX=9606 GN=TMF1 PE=1 SV=2 4.41 1679.9 - 1.74E+06 - - - -1.1095 - 1.837 0.211 - 207.4 1 2 1 -0.0014 11 0 0 0 5.53E+07 5.08E+07 - - - 2.6197 0.9998 221125_WJC_METTL3_EV_vs_WT_F06.06977.06977.2 0.00229 18-Oct K.GAGDLSVVKK.M sp|Q9BY49|PECR_HUMAN 1 972.5604 1.11 77557 6977 2 972.559506 487.2875 Peroxisomal trans-2-enoyl-CoA reductase OS=Homo sapiens OX=9606 GN=PECR PE=1 SV=2 8.59 1680.1 - 568878 - - - -0.9141 - 2.139 0.419 - 370.1 1 2 0 -0.0009 10 0 0 0 2.83E+07 2.54E+07 - - - 4.2578 0.9997 221125_WJC_METTL3_EV_vs_WT_F06.06982.06982.2 0.00142 16-Oct R.TATQLAVNK[136.11].L "sp|Q99832|TCPH_HUMAN,tr|F8WAM2|F8WAM2_HUMAN" 2 952.5433 0.4 77560 6982 2 952.543314 477.2789 T-complex protein 1 subunit eta OS=Homo sapiens OX=9606 GN=CCT7 PE=1 SV=2 8.41 1680.7 - 1.99E+06 - - - 0.0199 - 1.888 0.379 - 388.2 1 2 0 0 9 0 0 0 2.61E+07 6.52E+07 - - - 3.6789 0.9987 221125_WJC_METTL3_EV_vs_WT_F06.06988.06988.2 0.869 12-Jul K.ITITNDK[136.11].G "sp|P54652|HSP72_HUMAN,sp|P0DMV8|HS71A_HUMAN,sp|P34931|HS71L_HUMAN,sp|P11142|HSP7C_HUMAN,sp|P0DMV9|HS71B_HUMAN,sp|P17066|HSP76_HUMAN,tr|E9PNE6|E9PNE6_HUMAN,tr|A8K7Q2|A8K7Q2_HUMAN,tr|E9PKE3|E9PKE3_HUMAN,tr|E9PM13|E9PM13_HUMAN,tr|E9PS65|E9PS65_HUMAN,tr|Q53FA3|Q53FA3_HUMAN,tr|V9GZ37|V9GZ37_HUMAN,tr|A0A0G2JIW1|A0A0G2JIW1_HUMAN" 14 811.4531 1.54 77564 6988 2 811.452071 406.7338 Heat shock-related 70 kDa protein 2 OS=Homo sapiens OX=9606 GN=HSPA2 PE=1 SV=1 5.84 1681.5 - 9.84E+06 - - - -1.2471 - 1.524 0.277 - 154 1 2 0 -0.001 7 0 0 0 3.09E+08 2.01E+08 - - - 2.4216 0.9989 221125_WJC_METTL3_EV_vs_WT_F06.06989.06989.2 0.585 12-Aug R.RQDLLSR.Y "sp|P58107|EPIPL_HUMAN,sp|P58107|EPIPL_HUMAN,sp|P58107|EPIPL_HUMAN,sp|P58107|EPIPL_HUMAN,tr|A0A075B730|A0A075B730_HUMAN,tr|A0A075B730|A0A075B730_HUMAN,tr|A0A075B730|A0A075B730_HUMAN,tr|A0A075B730|A0A075B730_HUMAN" 8 886.4985 1.5 77565 6989 2 886.498218 444.2565 Epiplakin OS=Homo sapiens OX=9606 GN=EPPK1 PE=1 SV=3 9.6 1681.6 - 1.92E+06 - - - -0.2775 - 1.58 0.243 - 182.3 1 2 0 -0.0002 7 0 0 0 8.63E+07 5.76E+07 - - - 2.2851 0.9993 221125_WJC_METTL3_EV_vs_WT_F06.06990.06990.2 0.00805 18-Jul R.VQESADELQK[136.11].M "sp|P84085|ARF5_HUMAN,tr|C9J1Z8|C9J1Z8_HUMAN" 2 1153.5706 1.19 77566 6990 2 1153.569481 577.7926 ADP-ribosylation factor 5 OS=Homo sapiens OX=9606 GN=ARF5 PE=1 SV=2 4.14 1681.6 - 6.20E+06 - - - -0.9978 - 1.657 0.319 - 210.1 1 2 0 -0.0012 10 0 0 0 3.58E+08 3.01E+08 - - - 2.8064 0.9975 221125_WJC_METTL3_EV_vs_WT_F06.06992.06992.2 0.616 14-Aug R.HLTGEFEK.K "sp|P62826|RAN_HUMAN,tr|H0YFC6|H0YFC6_HUMAN,tr|B5MDF5|B5MDF5_HUMAN,tr|J3KQE5|J3KQE5_HUMAN,tr|F5H018|F5H018_HUMAN" 5 959.4712 0.89 77568 6992 2 959.471338 480.7429 GTP-binding nuclear protein Ran OS=Homo sapiens OX=9606 GN=RAN PE=1 SV=3 5.4 1681.9 - 352529 - - - 0.0959 - 1.372 0.221 - 202.5 1 2 0 0.0001 8 0 0 0 4.93E+07 5.52E+07 - - - 1.6271 0.997 221125_WJC_METTL3_EV_vs_WT_F06.06995.06995.2 0.000377 18-Nov K.SATYVNTEGR.A "sp|P28331|NDUS1_HUMAN,tr|B4DJ81|B4DJ81_HUMAN" 2 1096.5149 1.3 77569 6995 2 1096.50906 549.2647 "NADH-ubiquinone oxidoreductase 75 kDa subunit, mitochondrial OS=Homo sapiens OX=9606 GN=NDUFS1 PE=1 SV=3" 5.72 1682.3 - 1.14E+06 - - - -5.3278 - 2.205 0.487 - 643.8 1 2 0 -0.0058 10 0 0 0 2.47E+07 1.90E+07 - - - 4.8433 0.9989 221125_WJC_METTL3_EV_vs_WT_F06.06997.06997.2 0.00122 20-Sep R.EPALGPHGPSR.H "tr|K7EQG2|K7EQG2_HUMAN,tr|E9PAU2|E9PAU2_HUMAN,tr|A0A087WZ13|A0A087WZ13_HUMAN" 3 1116.5676 0.9 77571 6997 2 1116.565184 559.2911 Uncharacterized protein (Fragment) OS=Homo sapiens OX=9606 PE=1 SV=1 6.85 1682.4 - 1.10E+07 - - - -2.1691 - 1.352 0.447 - 203.7 1 2 0 -0.0024 11 0 0 0 2.83E+08 3.16E+08 - - - 3.1576 0.8916 221125_WJC_METTL3_EV_vs_WT_F06.06998.06998.2 6.63 16-Oct P.ALGPHGPSR[166.11].H "tr|K7EQG2|K7EQG2_HUMAN,tr|E9PAU2|E9PAU2_HUMAN,tr|A0A087WZ13|A0A087WZ13_HUMAN" 3 900.4805 1.67 77572 6998 2 900.480349 451.2475 Uncharacterized protein (Fragment) OS=Homo sapiens OX=9606 PE=1 SV=1 9.8 1682.5 - 1.94E+06 - - - -0.1888 - 1.661 0.172 - 446.8 1 1 0 -0.0002 9 0 0 0 1.61E+08 9.65E+07 - - - 1.7793 0.9997 221125_WJC_METTL3_EV_vs_WT_F06.07003.07003.3 6.42E-05 13/36 R.LLQQNTQLKR.F "sp|Q01664|TFAP4_HUMAN,tr|I3L254|I3L254_HUMAN" 2 1240.7252 1.64 77575 7003 3 1240.723622 414.5823 Transcription factor AP-4 OS=Homo sapiens OX=9606 GN=TFAP4 PE=1 SV=2 11 1683.2 - 2.58E+06 - - - -1.2469 - 2.18 0.313 - 188.8 1 2 0 -0.0015 10 0 0 0 1.37E+08 8.36E+07 - - - 4.3052 0.9977 221125_WJC_METTL3_EV_vs_WT_F06.07005.07005.2 0.00587 16-Oct R.QITQNTDYR.L sp|Q92896|GSLG1_HUMAN 1 1137.5415 0.8 77577 7005 2 1137.539119 569.778 Golgi apparatus protein 1 OS=Homo sapiens OX=9606 GN=GLG1 PE=1 SV=2 5.84 1683.4 - 686822 - - - -2.05 - 1.53 0.282 - 373 1 2 0 -0.0023 9 0 0 0 2.34E+07 2.93E+07 - - - 2.3534 0.8735 221125_WJC_METTL3_EV_vs_WT_F06.07010.07010.2 0.314 14-Jun A.GDLSVVKK.M sp|Q9BY49|PECR_HUMAN 1 844.5018 1.46 77580 7010 2 844.501409 423.2582 Peroxisomal trans-2-enoyl-CoA reductase OS=Homo sapiens OX=9606 GN=PECR PE=1 SV=2 8.59 1684 - 1.92E+06 - - - -0.4843 - 1.488 0.193 - 125.5 1 1 0 -0.0004 8 0 0 0 4.26E+07 2.93E+07 - - - 1.665 0.9997 221125_WJC_METTL3_EV_vs_WT_F06.07011.07011.2 0.00117 20-Oct R.EVADSYAQNAK.V sp|Q9H5V9|STEEP_HUMAN 1 1194.5517 0.77 77581 7011 2 1194.551068 598.2831 STING ER exit protein OS=Homo sapiens OX=9606 GN=STEEP1 PE=1 SV=1 4.37 1684.1 - 366068 - - - -0.5132 - 1.673 0.41 - 240.4 1 2 0 -0.0006 11 0 0 0 2.72E+07 3.54E+07 - - - 3.4612 0.9938 221125_WJC_METTL3_EV_vs_WT_F06.07016.07016.2 0.666 14-Jul R.C[160.03]IIPNHEK[136.11].R "sp|P35580|MYH10_HUMAN,sp|P35749|MYH11_HUMAN,sp|P35579|MYH9_HUMAN" 3 1017.5157 0.33 77584 7016 2 1017.515097 509.7651 Myosin-10 OS=Homo sapiens OX=9606 GN=MYH10 PE=1 SV=3 6.74 1684.7 - 1.83E+06 - - - -0.5936 - 1.193 0.19 - 152.2 1 2 0 -0.0006 8 0 0 0 1.37E+07 4.15E+07 - - - 0.9764 0.9999 221125_WJC_METTL3_EV_vs_WT_F06.07018.07018.2 3.89E-05 20-Aug R.EVADSYAQNAK[136.11].V sp|Q9H5V9|STEEP_HUMAN 1 1202.5659 0.77 77586 7018 2 1202.565712 602.2902 STING ER exit protein OS=Homo sapiens OX=9606 GN=STEEP1 PE=1 SV=1 4.37 1684.9 - 720489 - - - -0.1405 - 1.768 0.541 - 181 1 2 0 -0.0002 11 0 0 0 2.72E+07 3.54E+07 - - - 4.5783 0.9998 221125_WJC_METTL3_EV_vs_WT_F06.07019.07019.2 0.00407 18-Oct R.LLQQNTQLKR.F "sp|Q01664|TFAP4_HUMAN,tr|I3L254|I3L254_HUMAN" 2 1240.7252 1.7 77587 7019 2 1240.725275 621.3699 Transcription factor AP-4 OS=Homo sapiens OX=9606 GN=TFAP4 PE=1 SV=2 11 1685 - 586637 - - - 0.0854 - 2.128 0.42 - 473.2 1 2 0 0.0001 10 0 0 0 1.57E+07 9.24E+06 - - - 4.251 0.9963 221125_WJC_METTL3_EV_vs_WT_F06.07022.07022.2 0.176 22-Aug K.IVQAEGEAEAAK.M "sp|Q99623|PHB2_HUMAN,tr|F5H3X6|F5H3X6_HUMAN,tr|F5GY37|F5GY37_HUMAN" 3 1214.6143 0.76 77590 7022 2 1214.613022 608.3144 Prohibitin-2 OS=Homo sapiens OX=9606 GN=PHB2 PE=1 SV=2 4.25 1685.4 - 200260 - - - -1.0374 - 1.185 0.267 - 135.6 1 2 0 -0.0013 12 0 0 0 5.32E+06 7.04E+06 - - - 1.4593 0.9995 221125_WJC_METTL3_EV_vs_WT_F06.07025.07025.3 0.0411 Sep-44 R.ISKPGAVSTPVK.H "sp|Q07157|ZO1_HUMAN,tr|A0A087X0K9|A0A087X0K9_HUMAN,tr|G5E9E7|G5E9E7_HUMAN,tr|A0A0G2JNH2|A0A0G2JNH2_HUMAN,tr|G3V1L9|G3V1L9_HUMAN,tr|A0A7I2V5U5|A0A7I2V5U5_HUMAN" 6 1182.6972 0.88 77591 7025 3 1182.697427 395.2397 Tight junction protein ZO-1 OS=Homo sapiens OX=9606 GN=TJP1 PE=1 SV=3 10 1685.8 - 1.55E+06 - - - 0.1725 - 1.669 0.35 - 53 1 2 0 0.0002 12 0 0 0 3.20E+07 3.63E+07 - - - 3.8619 0.9995 221125_WJC_METTL3_EV_vs_WT_F06.07026.07026.2 0.0515 18-Sep R.LLQQNTQLK[136.11]R[166.11].F "sp|Q01664|TFAP4_HUMAN,tr|I3L254|I3L254_HUMAN" 2 1258.7476 1.7 77592 7026 2 1258.748045 630.3811 Transcription factor AP-4 OS=Homo sapiens OX=9606 GN=TFAP4 PE=1 SV=2 11 1685.9 - 619593 - - - 0.3225 - 1.756 0.344 - 252 1 2 0 0.0004 10 0 0 0 1.57E+07 9.24E+06 - - - 3.1533 0.9978 221125_WJC_METTL3_EV_vs_WT_F06.07028.07028.2 0.00522 14-Jun K.YHSDDYIK[136.11].F "sp|Q13547|HDAC1_HUMAN,tr|Q5TEE2|Q5TEE2_HUMAN" 2 1047.4753 1.51 77594 7028 2 1047.476289 524.7449 Histone deacetylase 1 OS=Homo sapiens OX=9606 GN=HDAC1 PE=1 SV=1 5.21 1686.2 - 543306 - - - 0.968 - 1.34 0.273 - 144.9 1 2 0 0.001 8 0 0 0 1.86E+08 1.23E+08 - - - 1.9397 0.9998 221125_WJC_METTL3_EV_vs_WT_F06.07029.07029.2 0.000131 14-Oct K.YHSDDYIK.F "sp|Q13547|HDAC1_HUMAN,tr|Q5TEE2|Q5TEE2_HUMAN" 2 1039.4611 1.51 77595 7029 2 1039.462733 520.7378 Histone deacetylase 1 OS=Homo sapiens OX=9606 GN=HDAC1 PE=1 SV=1 5.21 1686.3 - 540671 - - - 1.5951 - 2.028 0.528 - 468 1 2 0 0.0017 8 0 0 0 1.86E+08 1.23E+08 - - - 5.0727 0.9997 221125_WJC_METTL3_EV_vs_WT_F06.07030.07030.2 3.27E-06 20-Oct R.YESQQNGTPLK[136.11].V "sp|Q5JSZ5|PRC2B_HUMAN,tr|A0A804HKC3|A0A804HKC3_HUMAN,tr|A0A804HJR4|A0A804HJR4_HUMAN" 3 1271.6237 1.66 77596 7030 2 1271.626165 636.8191 Protein PRRC2B OS=Homo sapiens OX=9606 GN=PRRC2B PE=1 SV=2 6 1686.4 - 528764 - - - 1.9141 - 1.952 0.531 - 258.7 1 2 0 0.0024 11 0 0 0 8.72E+07 5.27E+07 - - - 4.7716 0.8302 221125_WJC_METTL3_EV_vs_WT_F06.07034.07034.2 0.0845 18-Jun R.FR[166.11]TDEADDVK[136.11].F "sp|O60524|NEMF_HUMAN,tr|G3V5V3|G3V5V3_HUMAN,tr|G3V4D9|G3V4D9_HUMAN" 3 1212.5742 10.12 77600 7034 2 1212.578967 607.2944 Nuclear export mediator factor NEMF OS=Homo sapiens OX=9606 GN=NEMF PE=1 SV=4 4.23 1686.9 - 216013 - - - 3.9717 - 1.398 0.249 - 156.1 1 2 1 0.0048 10 0 0 0 2.61E+07 2.58E+06 - - - 1.8138 0.9572 221125_WJC_METTL3_EV_vs_WT_F06.07035.07035.2 3.91 22-May R.ALSSEGKPYVTK.E "sp|Q13813|SPTN1_HUMAN,tr|A0A0D9SF54|A0A0D9SF54_HUMAN,tr|A0A0D9SGF6|A0A0D9SGF6_HUMAN,tr|A0A0D9SFH4|A0A0D9SFH4_HUMAN" 4 1278.682 1.86 77601 7035 2 1278.681225 640.3483 "Spectrin alpha chain, non-erythrocytic 1 OS=Homo sapiens OX=9606 GN=SPTAN1 PE=1 SV=3" 8.54 1687.1 - 112218 - - - -0.5803 - 1.01 0.121 - 50.8 4 2 0 -0.0007 12 0 0 0 8.84E+06 4.74E+06 - - - -0.3083 0.9998 221125_WJC_METTL3_EV_vs_WT_F06.07039.07039.3 0.000192 13/44 R.ALSSEGKPYVTK.E "sp|Q13813|SPTN1_HUMAN,tr|A0A0D9SF54|A0A0D9SF54_HUMAN,tr|A0A0D9SGF6|A0A0D9SGF6_HUMAN,tr|A0A0D9SFH4|A0A0D9SFH4_HUMAN" 4 1278.682 1.57 77603 7039 3 1278.683694 427.2346 "Spectrin alpha chain, non-erythrocytic 1 OS=Homo sapiens OX=9606 GN=SPTAN1 PE=1 SV=3" 8.54 1687.5 - 1.50E+06 - - - 1.3506 - 2.106 0.372 - 208.9 1 2 0 0.0017 12 0 0 0 8.79E+07 5.60E+07 - - - 4.7514 0.9988 221125_WJC_METTL3_EV_vs_WT_F06.07042.07042.2 7.47E-06 16-Sep K.QQLDSC[160.03]VTK.C "sp|Q96C01|F136A_HUMAN,tr|E7EQY1|E7EQY1_HUMAN" 2 1077.5125 1.6 77606 7042 2 1077.513546 539.7635 Protein FAM136A OS=Homo sapiens OX=9606 GN=FAM136A PE=1 SV=1 5.83 1687.7 - 2.53E+06 - - - 1.0088 - 1.879 0.211 - 356.7 1 2 0 0.0011 9 0 0 0 4.23E+07 2.65E+07 - - - 2.4239 0.9993 221125_WJC_METTL3_EV_vs_WT_F06.07043.07043.3 0.0186 Oct-44 R.ALSSEGK[136.11]PYVTK[136.11].E "sp|Q13813|SPTN1_HUMAN,tr|A0A0D9SF54|A0A0D9SF54_HUMAN,tr|A0A0D9SGF6|A0A0D9SGF6_HUMAN,tr|A0A0D9SFH4|A0A0D9SFH4_HUMAN" 4 1294.7104 1.53 77607 7043 3 1294.711403 432.5774 "Spectrin alpha chain, non-erythrocytic 1 OS=Homo sapiens OX=9606 GN=SPTAN1 PE=1 SV=3" 8.54 1687.8 - 1.17E+06 - - - 0.8002 - 1.914 0.286 - 125.5 1 2 0 0.001 12 0 0 0 8.61E+07 5.63E+07 - - - 3.5278 0.9962 221125_WJC_METTL3_EV_vs_WT_F06.07045.07045.2 0.000605 18-Oct K.MEQQQLEEQK.K "sp|Q9NRZ9|HELLS_HUMAN,tr|B1ALG6|B1ALG6_HUMAN,tr|A0A0B4J1V9|A0A0B4J1V9_HUMAN" 3 1289.5922 0.45 77609 7045 2 1289.598449 645.8034 Lymphoid-specific helicase OS=Homo sapiens OX=9606 GN=HELLS PE=1 SV=1 4.25 1688 - 259012 - - - 4.8721 - 2.021 0.406 - 464.6 1 2 0 0.0063 10 0 0 0 6.31E+06 1.41E+07 - - - 4.0017 0.764 221125_WJC_METTL3_EV_vs_WT_F06.07048.07048.2 0.182 14-Sep N.RFSGVPDR.F "sp|A0A075B6R9|KVD24_HUMAN,sp|A0A0C4DH68|KV224_HUMAN,sp|A2NJV5|KV229_HUMAN,sp|A0A075B6S2|KVD29_HUMAN,sp|A0A0A0MRZ7|KVD26_HUMAN" 5 932.4828 56.5 77610 7048 2 932.485525 467.2487 Probable non-functional immunoglobulin kappa variable 2D-24 OS=Homo sapiens OX=9606 GN=IGKV2D-24 PE=1 SV=1 9.6 1688.4 - 3.90E+06 - - - 2.9073 - 1.605 0.237 - 204.8 1 1 0 0.0027 8 0 0 0 3.03E+08 5.37E+06 - - - 2.2176 0.9985 221125_WJC_METTL3_EV_vs_WT_F06.07050.07050.3 0.404 Oct-40 K.IPHGVSGVQDR[166.11].M sp|Q9BPU6|DPYL5_HUMAN 1 1173.613 0.22 77612 7050 3 1173.614207 392.2116 Dihydropyrimidinase-related protein 5 OS=Homo sapiens OX=9606 GN=DPYSL5 PE=1 SV=1 6.74 1688.5 - 1.05E+06 - - - 1.037 - 2.12 0.218 - 121.9 1 2 0 0.0012 11 0 0 0 1.41E+07 6.39E+07 - - - 3.1048 0.9996 221125_WJC_METTL3_EV_vs_WT_F06.07051.07051.2 0.000163 18-Oct K.MEQQQLEEQK[136.11].K "sp|Q9NRZ9|HELLS_HUMAN,tr|B1ALG6|B1ALG6_HUMAN,tr|A0A0B4J1V9|A0A0B4J1V9_HUMAN" 3 1297.6064 0.44 77613 7051 2 1297.608055 649.8105 Lymphoid-specific helicase OS=Homo sapiens OX=9606 GN=HELLS PE=1 SV=1 4.25 1688.7 - 727736 - - - 1.3016 - 1.859 0.415 - 494.7 1 2 0 0.0017 10 0 0 0 7.01E+06 1.59E+07 - - - 3.8364 0.9987 221125_WJC_METTL3_EV_vs_WT_F06.07052.07052.2 0.00134 18-Jul R.YSGPAPPPNR.F sp|Q9BRD0|BUD13_HUMAN 1 1054.5196 0.91 77614 7052 2 1054.522302 528.2671 BUD13 homolog OS=Homo sapiens OX=9606 GN=BUD13 PE=1 SV=1 8.75 1688.8 - 572747 - - - 2.5689 - 1.754 0.361 - 129.4 1 2 0 0.0027 10 0 0 0 2.63E+07 2.90E+07 - - - 3.2749 0.9895 221125_WJC_METTL3_EV_vs_WT_F06.07054.07054.2 0.00431 20-Nov K.TQTPAAQPVPR[166.11].P "sp|Q6P1J9|CDC73_HUMAN,tr|A0A1B0GUB2|A0A1B0GUB2_HUMAN,tr|A0A3B3IRP5|A0A3B3IRP5_HUMAN" 3 1174.6334 1.4 77616 7054 2 1174.633518 588.324 Parafibromin OS=Homo sapiens OX=9606 GN=CDC73 PE=1 SV=1 9.41 1689.1 - 433948 - - - 0.1081 - 2.222 0.414 - 488.3 1 1 0 0.0001 11 0 0 0 2.11E+07 1.50E+07 - - - 4.2586 0.9998 221125_WJC_METTL3_EV_vs_WT_F06.07057.07057.2 7.36E-06 20-Dec R.YESQQNGTPLK.V "sp|Q5JSZ5|PRC2B_HUMAN,tr|A0A804HKC3|A0A804HKC3_HUMAN,tr|A0A804HJR4|A0A804HJR4_HUMAN" 3 1263.6095 1.66 77618 7057 2 1263.61133 632.812 Protein PRRC2B OS=Homo sapiens OX=9606 GN=PRRC2B PE=1 SV=2 6 1689.4 - 4.17E+06 - - - 1.4237 - 2.206 0.552 - 413.7 1 2 0 0.0018 11 0 0 0 8.73E+07 5.27E+07 - - - 5.2578 0.9996 221125_WJC_METTL3_EV_vs_WT_F06.07059.07059.2 0.00182 14-Aug R.LSVDYGK[136.11]K[136.11].S "sp|P0DPH7|TBA3C_HUMAN,sp|Q71U36|TBA1A_HUMAN,sp|P0DPH8|TBA3D_HUMAN,sp|P68366|TBA4A_HUMAN,sp|P68363|TBA1B_HUMAN,sp|Q9BQE3|TBA1C_HUMAN,tr|C9JJQ8|C9JJQ8_HUMAN,tr|C9JDS9|C9JDS9_HUMAN,tr|C9JQ00|C9JQ00_HUMAN,tr|C9JEV8|C9JEV8_HUMAN,tr|F5H5D3|F5H5D3_HUMAN,tr|F8VQQ4|F8VQQ4_HUMAN" 12 924.5251 0.57 77619 7059 2 924.526341 463.2698 Tubulin alpha-3C chain OS=Homo sapiens OX=9606 GN=TUBA3C PE=1 SV=1 8.5 1689.6 - 8.42E+06 - - - 1.3066 - 1.741 0.395 - 213.5 1 2 0 0.0012 8 0 0 0 2.63E+08 4.61E+08 - - - 3.6303 0.9997 221125_WJC_METTL3_EV_vs_WT_F06.07061.07061.2 0.019 18-Oct K.AGVSTNISTK[136.11].H "sp|P52948|NUP98_HUMAN,tr|A0A3B3ITD8|A0A3B3ITD8_HUMAN" 2 984.5331 1.79 77621 7061 2 984.533049 493.2738 Nuclear pore complex protein Nup98-Nup96 OS=Homo sapiens OX=9606 GN=NUP98 PE=1 SV=4 8.8 1689.7 - 1.72E+06 - - - -0.0772 - 1.952 0.348 - 232.9 1 2 0 -0.0001 10 0 0 0 1.13E+08 6.28E+07 - - - 3.4783 0.9964 221125_WJC_METTL3_EV_vs_WT_F06.07063.07063.3 0.00437 Aug-40 R.IEGDNENK[136.11]LPR[166.11].E "sp|P51114|FXR1_HUMAN,tr|E7EU85|E7EU85_HUMAN,tr|E9PFF5|E9PFF5_HUMAN,tr|B4DXZ6|B4DXZ6_HUMAN" 4 1301.6694 2.83 77623 7063 3 1301.67034 434.8971 Fragile X mental retardation syndrome-related protein 1 OS=Homo sapiens OX=9606 GN=FXR1 PE=1 SV=3 4.68 1689.9 - 775302 - - - 0.6845 - 1.681 0.312 - 100.1 1 2 1 0.0009 11 0 0 0 4.35E+07 1.54E+07 - - - 3.4937 0.9985 221125_WJC_METTL3_EV_vs_WT_F06.07064.07064.3 0.0044 Nov-40 R.EGPGRPPLDGR.D "sp|Q9UPN6|SCAF8_HUMAN,tr|A0A0A0MT33|A0A0A0MT33_HUMAN" 2 1149.5891 0.51 77624 7064 3 1149.591012 384.2036 SR-related and CTD-associated factor 8 OS=Homo sapiens OX=9606 GN=SCAF8 PE=1 SV=1 6.17 1690 - 603198 - - - 1.6893 - 1.863 0.273 - 141.3 1 2 0 0.0019 11 0 0 0 2.72E+07 5.30E+07 - - - 3.3507 0.8277 221125_WJC_METTL3_EV_vs_WT_F06.07065.07065.2 1.72 14-Jun P.DGIISK[136.11]PK[136.11].N sp|Q86U44|MTA70_HUMAN 1 872.5302 0.01 77625 7065 2 872.530851 437.2724 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 8.59 1690.1 - 492881 - - - 0.7255 - 1.25 0.241 - 92.1 1 1 0 0.0006 8 0 0 0 9.99E+04 1.27E+07 - - - 1.4938 0.9983 221125_WJC_METTL3_EV_vs_WT_F06.07067.07067.2 0.0229 20-Jul R.SFANEEGEAQK.F "sp|Q03518|TAP1_HUMAN,tr|A0A140T9T7|A0A140T9T7_HUMAN" 2 1208.5309 1.04 77627 7067 2 1208.53395 605.2727 Antigen peptide transporter 1 OS=Homo sapiens OX=9606 GN=TAP1 PE=1 SV=2 4.25 1690.4 - 144689 - - - 2.4857 - 1.315 0.433 - 119.5 1 2 0 0.003 11 0 0 0 1.81E+06 1.74E+06 - - - 2.979 0.9645 221125_WJC_METTL3_EV_vs_WT_F06.07070.07070.2 0.00829 12-Jul L.SVDYGKK.S "sp|P0DPH7|TBA3C_HUMAN,sp|Q71U36|TBA1A_HUMAN,sp|P0DPH8|TBA3D_HUMAN,sp|P68366|TBA4A_HUMAN,sp|P68363|TBA1B_HUMAN,sp|Q9BQE3|TBA1C_HUMAN,tr|C9JJQ8|C9JJQ8_HUMAN,tr|C9JDS9|C9JDS9_HUMAN,tr|C9JQ00|C9JQ00_HUMAN,tr|C9JEV8|C9JEV8_HUMAN,tr|F5H5D3|F5H5D3_HUMAN,tr|F8VQQ4|F8VQQ4_HUMAN" 12 795.4127 0.54 77628 7070 2 795.413388 398.7136 Tubulin alpha-3C chain OS=Homo sapiens OX=9606 GN=TUBA3C PE=1 SV=1 8.22 1690.8 - 4.29E+06 - - - 0.9039 - 1.458 0.382 - 142.8 1 1 0 0.0007 7 0 0 0 1.68E+08 3.09E+08 - - - 3.057 0.9999 221125_WJC_METTL3_EV_vs_WT_F06.07072.07072.2 1.17E-05 13/18 R.IVGHLTHALK[136.11].Q "sp|P24752|THIL_HUMAN,tr|A0A5F9ZHD4|A0A5F9ZHD4_HUMAN,tr|A0A5F9ZHJ0|A0A5F9ZHJ0_HUMAN,tr|A0A5F9ZHL1|A0A5F9ZHL1_HUMAN,tr|A0A5F9ZI66|A0A5F9ZI66_HUMAN" 5 1095.6644 1.2 77630 7072 2 1095.665479 548.8395 "Acetyl-CoA acetyltransferase, mitochondrial OS=Homo sapiens OX=9606 GN=ACAT1 PE=1 SV=1" 8.76 1690.9 - 1.40E+06 - - - 0.972 - 2.416 0.498 - 576.3 1 2 0 0.0011 10 0 0 0 1.30E+08 1.09E+08 - - - 5.1811 0.9972 221125_WJC_METTL3_EV_vs_WT_F06.07074.07074.3 0.0215 Aug-40 R.EGPGR[166.11]PPLDGR[166.11].D "sp|Q9UPN6|SCAF8_HUMAN,tr|A0A0A0MT33|A0A0A0MT33_HUMAN" 2 1169.6056 1.09 77632 7074 3 1169.606268 390.8758 SR-related and CTD-associated factor 8 OS=Homo sapiens OX=9606 GN=SCAF8 PE=1 SV=1 6.17 1691.1 - 838558 - - - 0.5626 - 1.674 0.233 - 100.6 1 2 0 0.0007 11 0 0 0 2.71E+07 2.50E+07 - - - 2.6012 0.9998 221125_WJC_METTL3_EV_vs_WT_F06.07078.07078.2 0.000141 18-Oct K.MQEQQADLQR[166.11].R "sp|Q14203|DCTN1_HUMAN,tr|A0A804CDA6|A0A804CDA6_HUMAN,tr|E7EX90|E7EX90_HUMAN,tr|A0A7P0Z4C3|A0A7P0Z4C3_HUMAN,tr|Q6AWB1|Q6AWB1_HUMAN" 5 1255.5855 1.8 77636 7078 2 1255.586945 628.8 Dynactin subunit 1 OS=Homo sapiens OX=9606 GN=DCTN1 PE=1 SV=3 4.37 1691.6 - 279831 - - - 1.1867 - 1.951 0.48 - 436.9 1 2 0 0.0015 10 0 0 0 1.95E+08 1.09E+08 - - - 4.4514 0.9999 221125_WJC_METTL3_EV_vs_WT_F06.07081.07081.2 3.37E-05 20-Nov R.ISNSDLSGSAR[166.11].R "sp|P39880|CUX1_HUMAN,tr|A0A2R8Y852|A0A2R8Y852_HUMAN" 2 1115.5446 1.45 77637 7081 2 1115.54529 558.7796 Homeobox protein cut-like 1 OS=Homo sapiens OX=9606 GN=CUX1 PE=1 SV=3 5.84 1691.9 - 4.38E+06 - - - 0.5863 - 2.306 0.487 - 359.5 1 2 0 0.0007 11 0 0 0 3.04E+08 2.09E+08 - - - 4.898 0.9993 221125_WJC_METTL3_EV_vs_WT_F06.07083.07083.3 1.05E-05 Oct-36 K.YEAIVEENK[136.11]K[136.11].L "sp|Q99417|MYCBP_HUMAN,tr|A0A087WV05|A0A087WV05_HUMAN" 2 1237.6525 2.04 77639 7083 3 1237.653206 413.5581 c-Myc-binding protein OS=Homo sapiens OX=9606 GN=MYCBP PE=1 SV=3 4.79 1692.1 - 2.19E+06 - - - 0.5559 - 2.01 0.264 - 110 1 2 0 0.0007 10 0 0 0 1.38E+08 6.73E+07 - - - 3.522 0.9998 221125_WJC_METTL3_EV_vs_WT_F06.07084.07084.2 6.69E-05 18-Oct K.MQEQQADLQR.R "sp|Q14203|DCTN1_HUMAN,tr|A0A804CDA6|A0A804CDA6_HUMAN,tr|E7EX90|E7EX90_HUMAN,tr|A0A7P0Z4C3|A0A7P0Z4C3_HUMAN,tr|Q6AWB1|Q6AWB1_HUMAN" 5 1245.5772 1.8 77640 7084 2 1245.57897 623.7959 Dynactin subunit 1 OS=Homo sapiens OX=9606 GN=DCTN1 PE=1 SV=3 4.37 1692.2 - 654082 - - - 1.4331 - 2.228 0.529 - 462.3 1 2 0 0.0018 10 0 0 0 1.95E+08 1.08E+08 - - - 5.1838 0.9924 221125_WJC_METTL3_EV_vs_WT_F06.07085.07085.2 0.0126 14-Oct K.SKFDEMAK.A "sp|O15347|HMGB3_HUMAN,tr|E9PES6|E9PES6_HUMAN,tr|E7EQU1|E7EQU1_HUMAN,tr|E7ES08|E7ES08_HUMAN" 4 954.4481 0.29 77641 7085 2 954.448934 478.2313 High mobility group protein B3 OS=Homo sapiens OX=9606 GN=HMGB3 PE=1 SV=4 5.79 1692.3 - 585622 - - - 0.9073 - 1.687 0.316 - 308.1 1 2 1 0.0009 8 0 0 0 3.11E+07 1.06E+08 - - - 2.9519 0.9999 221125_WJC_METTL3_EV_vs_WT_F06.07086.07086.2 0.0235 22-Nov K.VGGTSDVEVNEK[136.11].K "sp|P10809|CH60_HUMAN,tr|A0A7I2V2X6|A0A7I2V2X6_HUMAN,tr|A0A7I2YQK6|A0A7I2YQK6_HUMAN,tr|A0A7I2V599|A0A7I2V599_HUMAN" 4 1240.6027 1.15 77642 7086 2 1240.603825 621.3086 "60 kDa heat shock protein, mitochondrial OS=Homo sapiens OX=9606 GN=HSPD1 PE=1 SV=2" 4.14 1692.4 - 497371 - - - 0.9383 - 2.368 0.491 - 409.8 1 2 0 0.0012 12 0 0 0 2.06E+07 1.79E+07 - - - 4.9353 0.9998 221125_WJC_METTL3_EV_vs_WT_F06.07087.07087.2 0.000149 16/28 K.VLTANSNPSSPSAAK.R sp|Q9NV56|MRGBP_HUMAN 1 1442.7365 0.96 77643 7087 2 1442.739277 722.3755 MRG\MORF4L-binding protein OS=Homo sapiens OX=9606 GN=MRGBP PE=1 SV=1 8.72 1692.6 - 467531 - - - 1.9096 - 2.422 0.548 - 698.3 1 2 0 0.0028 15 0 0 0 1.92E+07 2.00E+07 - - - 5.2625 0.9977 221125_WJC_METTL3_EV_vs_WT_F06.07092.07092.2 0.01 16-Aug K.DYNVTANSK.L "sp|P00338|LDHA_HUMAN,tr|F5GXH2|F5GXH2_HUMAN,tr|F5GYU2|F5GYU2_HUMAN,tr|F5GXY2|F5GXY2_HUMAN" 4 1010.4669 1.46 77646 7092 2 1010.465414 506.2407 L-lactate dehydrogenase A chain OS=Homo sapiens OX=9606 GN=LDHA PE=1 SV=2 5.83 1693.2 - 1.60E+06 - - - -1.4597 - 1.415 0.269 - 206 1 2 0 -0.0015 9 0 0 0 9.73E+07 6.64E+07 - - - 2.0316 0.9841 221125_WJC_METTL3_EV_vs_WT_F06.07094.07094.2 0.0017 20-Sep K.TQTPAAQPVPR.P "sp|Q6P1J9|CDC73_HUMAN,tr|A0A1B0GUB2|A0A1B0GUB2_HUMAN,tr|A0A3B3IRP5|A0A3B3IRP5_HUMAN" 3 1164.6251 1.31 77648 7094 2 1164.625903 583.3198 Parafibromin OS=Homo sapiens OX=9606 GN=CDC73 PE=1 SV=1 9.41 1693.4 - 1.01E+06 - - - 0.6715 - 1.87 0.426 - 315.9 1 1 0 0.0008 11 0 0 0 1.98E+07 1.51E+07 - - - 3.8805 0.9998 221125_WJC_METTL3_EV_vs_WT_F06.07095.07095.2 0.000711 20-Oct R.ANVVTTPSTNR.K "sp|Q8IWZ3|ANKH1_HUMAN,tr|E9PDP5|E9PDP5_HUMAN,tr|H0Y472|H0Y472_HUMAN,tr|H0Y4P6|H0Y4P6_HUMAN,tr|H0Y785|H0Y785_HUMAN" 5 1158.5993 1.44 77649 7095 2 1158.599975 580.3069 Ankyrin repeat and KH domain-containing protein 1 OS=Homo sapiens OX=9606 GN=ANKHD1 PE=1 SV=1 9.79 1693.5 - 954775 - - - 0.5826 - 2.187 0.42 - 334.4 1 2 0 0.0007 11 0 0 0 1.23E+08 8.52E+07 - - - 4.2598 0.9964 221125_WJC_METTL3_EV_vs_WT_F06.07096.07096.2 0.154 16-Oct K.DTGHVYAMK[136.11].L sp|Q15208|STK38_HUMAN 1 1028.4841 5.93 77650 7096 2 1028.488709 515.2493 Serine\threonine-protein kinase 38 OS=Homo sapiens OX=9606 GN=STK38 PE=1 SV=1 6.74 1693.6 - 789013 - - - 4.5144 - 1.929 0.382 - 296.6 1 2 0 0.0046 9 0 0 0 2.98E+08 5.03E+07 - - - 3.7617 0.9573 221125_WJC_METTL3_EV_vs_WT_F06.07097.07097.3 0.149 Aug-40 R.LYHEATTDTYK[136.11].A sp|Q9BUB7|TMM70_HUMAN 1 1348.639 0.74 77651 7097 3 1348.637185 450.5536 "Transmembrane protein 70, mitochondrial OS=Homo sapiens OX=9606 GN=TMEM70 PE=1 SV=2" 5.32 1693.7 - 666526 - - - -1.3799 - 1.456 0.155 - 58.5 4 2 0 -0.0019 11 0 0 0 5.89E+06 7.91E+06 - - - 1.0562 0.9999 221125_WJC_METTL3_EV_vs_WT_F06.07101.07101.2 7.80E-05 14/18 R.IVGHLTHALK.Q "sp|P24752|THIL_HUMAN,tr|A0A5F9ZHD4|A0A5F9ZHD4_HUMAN,tr|A0A5F9ZHJ0|A0A5F9ZHJ0_HUMAN,tr|A0A5F9ZHL1|A0A5F9ZHL1_HUMAN,tr|A0A5F9ZI66|A0A5F9ZI66_HUMAN" 5 1087.6502 1.2 77653 7101 2 1087.650668 544.8324 "Acetyl-CoA acetyltransferase, mitochondrial OS=Homo sapiens OX=9606 GN=ACAT1 PE=1 SV=1" 8.76 1694.2 - 5.17E+06 - - - 0.4174 - 2.244 0.539 - 660 1 2 0 0.0005 10 0 0 0 1.30E+08 1.09E+08 - - - 5.278 0.9998 221125_WJC_METTL3_EV_vs_WT_F06.07102.07102.2 0.0273 20-Oct R.ANVVTTPSTNR[166.11].K "sp|Q8IWZ3|ANKH1_HUMAN,tr|E9PDP5|E9PDP5_HUMAN,tr|H0Y472|H0Y472_HUMAN,tr|H0Y4P6|H0Y4P6_HUMAN,tr|H0Y785|H0Y785_HUMAN" 5 1168.6076 1.58 77654 7102 2 1168.606987 585.3111 Ankyrin repeat and KH domain-containing protein 1 OS=Homo sapiens OX=9606 GN=ANKHD1 PE=1 SV=1 9.79 1694.3 - 831839 - - - -0.4989 - 2.234 0.394 - 375 1 2 0 -0.0006 11 0 0 0 1.35E+08 8.57E+07 - - - 4.1254 0.9997 221125_WJC_METTL3_EV_vs_WT_F06.07104.07104.3 0.00365 Dec-44 R.EAGLVAQHPPAR[166.11].R "sp|Q9BRJ6|CG050_HUMAN,tr|C9JQV0|C9JQV0_HUMAN,tr|H7C2R9|H7C2R9_HUMAN,tr|H7C0T1|H7C0T1_HUMAN" 4 1254.6708 1.42 77656 7104 3 1254.671301 419.2309 Uncharacterized protein C7orf50 OS=Homo sapiens OX=9606 GN=C7orf50 PE=1 SV=1 6.85 1694.4 - 1.92E+06 - - - 0.3682 - 2.154 0.323 - 192.4 1 2 0 0.0005 12 0 0 0 7.73E+07 5.44E+07 - - - 4.2679 0.9997 221125_WJC_METTL3_EV_vs_WT_F06.07108.07108.2 0.00259 14-Nov R.HELQC[160.03]DLR[166.11].R "sp|Q9C0C7|AMRA1_HUMAN,tr|A0A075B6T1|A0A075B6T1_HUMAN" 2 1079.5057 0.85 77658 7108 2 1079.503308 540.7602 Activating molecule in BECN1-regulated autophagy protein 1 OS=Homo sapiens OX=9606 GN=AMBRA1 PE=1 SV=2 5.32 1694.9 - 528280 - - - -2.2603 - 1.974 0.519 - 508 1 2 0 -0.0024 8 0 0 0 9.62E+06 1.13E+07 - - - 4.9246 0.9892 221125_WJC_METTL3_EV_vs_WT_F06.07119.07119.2 1.05E-06 13/22 K.TLDTGETPSETK[136.11].M sp|Q9UKZ1|CNO11_HUMAN 1 1285.6129 1.35 77665 7119 2 1285.623547 643.8137 CCR4-NOT transcription complex subunit 11 OS=Homo sapiens OX=9606 GN=CNOT11 PE=1 SV=1 4.14 1696.3 - 371240 - - - 8.2887 - 2.287 0.559 - 384.7 1 2 0 0.0107 12 0 0 0 8.37E+06 6.19E+06 - - - 5.343 0.9992 221125_WJC_METTL3_EV_vs_WT_F06.07120.07120.2 0.000449 16-Jul K.TC[160.03]EESSFC[160.03]K.R sp|Q14697|GANAB_HUMAN 1 1146.4322 0.78 77666 7120 2 1146.43334 574.2234 Neutral alpha-glucosidase AB OS=Homo sapiens OX=9606 GN=GANAB PE=1 SV=3 4.53 1696.4 - 816408 - - - 1.0293 - 1.276 0.414 - 165.7 1 2 0 0.0012 9 0 0 0 1.30E+07 1.65E+07 - - - 2.8036 0.9937 221125_WJC_METTL3_EV_vs_WT_F06.07126.07126.2 2.31E-05 12-Sep T.GHVYAMK.L sp|Q15208|STK38_HUMAN 1 804.3952 0.26 77670 7126 2 804.394906 403.2049 Serine\threonine-protein kinase 38 OS=Homo sapiens OX=9606 GN=STK38 PE=1 SV=1 8.6 1697.1 - 2.10E+06 - - - -0.4202 - 2.038 0.52 - 473.7 1 1 0 -0.0003 7 0 0 0 3.60E+07 1.38E+08 - - - 5.1375 1 221125_WJC_METTL3_EV_vs_WT_F06.07128.07128.2 2.93E-07 14/22 K.VGGTSDVEVNEK.K "sp|P10809|CH60_HUMAN,tr|A0A7I2V2X6|A0A7I2V2X6_HUMAN,tr|A0A7I2YQK6|A0A7I2YQK6_HUMAN,tr|A0A7I2V599|A0A7I2V599_HUMAN" 4 1232.5885 1.12 77672 7128 2 1232.588628 617.3015 "60 kDa heat shock protein, mitochondrial OS=Homo sapiens OX=9606 GN=HSPD1 PE=1 SV=2" 4.14 1697.3 - 1.37E+06 - - - 0.1355 - 2.428 0.605 - 393 1 2 0 0.0002 12 0 0 0 2.91E+07 2.59E+07 - - - 5.8435 0.9835 221125_WJC_METTL3_EV_vs_WT_F06.07131.07131.2 1.61 16-May K.VNIKPQVDR.Y sp|P23526|SAHH_HUMAN 1 1067.6087 0.99 77675 7131 2 1067.610222 534.8116 Adenosylhomocysteinase OS=Homo sapiens OX=9606 GN=AHCY PE=1 SV=4 8.72 1697.5 - 681351 - - - 1.3853 - 1.259 0.121 - 103.3 1 2 0 0.0015 9 0 0 0 1.48E+07 1.49E+07 - - - 0.6006 0.9998 221125_WJC_METTL3_EV_vs_WT_F06.07132.07132.3 0.00607 Nov-36 K.EVAEMDSVK[136.11]R[166.11].S "sp|P58107|EPIPL_HUMAN,tr|A0A075B730|A0A075B730_HUMAN" 2 1180.5877 3.15 77676 7132 3 1180.589208 394.5365 Epiplakin OS=Homo sapiens OX=9606 GN=EPPK1 PE=1 SV=3 4.68 1697.7 - 337490 - - - 1.2833 - 1.943 0.378 - 140.9 1 2 0 0.0015 10 0 0 0 1.22E+07 3.87E+06 - - - 4.6938 0.9455 221125_WJC_METTL3_EV_vs_WT_F06.07133.07133.2 0.211 20-May R.NLEEEEDGETK.G "sp|Q9H267|VP33B_HUMAN,tr|F5H008|F5H008_HUMAN,tr|A0A2R8YDQ0|A0A2R8YDQ0_HUMAN" 3 1291.5416 4.15 77677 7133 2 1291.535006 646.7781 Vacuolar protein sorting-associated protein 33B OS=Homo sapiens OX=9606 GN=VPS33B PE=1 SV=2 3.83 1697.8 - 278389 - - - -5.0823 - 0.999 0.337 - 62.4 1 2 0 -0.0066 11 0 0 0 7.95E+06 1.91E+06 - - - 1.5253 0.9997 221125_WJC_METTL3_EV_vs_WT_F06.07136.07136.2 0.0019 14-Nov R.KLDLSDTK.S "sp|Q96NR8|RDH12_HUMAN,sp|Q8TC12|RDH11_HUMAN" 2 918.5022 1.1 77678 7136 2 918.504475 460.2584 Retinol dehydrogenase 12 OS=Homo sapiens OX=9606 GN=RDH12 PE=1 SV=3 5.96 1698.2 - 2.13E+06 - - - 2.4638 - 2.179 0.528 - 496 1 2 0 0.0023 8 0 0 0 4.83E+07 4.39E+07 - - - 5.2891 0.964 221125_WJC_METTL3_EV_vs_WT_F06.07137.07137.2 0.00255 16-Oct L.VGHLTHALK.Q "sp|P24752|THIL_HUMAN,tr|A0A5F9ZHD4|A0A5F9ZHD4_HUMAN,tr|A0A5F9ZHJ0|A0A5F9ZHJ0_HUMAN,tr|A0A5F9ZHL1|A0A5F9ZHL1_HUMAN,tr|A0A5F9ZI66|A0A5F9ZI66_HUMAN" 5 974.5661 1.13 77679 7137 2 974.566093 488.2904 "Acetyl-CoA acetyltransferase, mitochondrial OS=Homo sapiens OX=9606 GN=ACAT1 PE=1 SV=1" 8.74 1698.3 - 1.35E+06 - - - -0.0585 - 1.777 0.284 - 328.9 1 1 0 -0.0001 9 0 0 0 3.11E+07 2.74E+07 - - - 2.8019 0.8567 221125_WJC_METTL3_EV_vs_WT_F06.07138.07138.2 0.0384 20-Jul K.EGNASGVSLLE.A "sp|Q05639|EF1A2_HUMAN,tr|A0A2U3TZH3|A0A2U3TZH3_HUMAN" 2 1074.5193 - 77680 7138 2 1074.520105 538.2669 Elongation factor 1-alpha 2 OS=Homo sapiens OX=9606 GN=EEF1A2 PE=1 SV=1 4.24 1698.4 - 1.03E+06 - - - 0.7315 - 1.434 0.223 - 116.9 1 1 0 0.0008 11 0 0 0 - - - - - 1.663 1 221125_WJC_METTL3_EV_vs_WT_F06.07139.07139.2 7.50E-05 22-Dec K.TLDTGETPSETK.M sp|Q9UKZ1|CNO11_HUMAN 1 1277.5987 1.35 77681 7139 2 1277.599323 639.8066 CCR4-NOT transcription complex subunit 11 OS=Homo sapiens OX=9606 GN=CNOT11 PE=1 SV=1 4.14 1698.5 - 317232 - - - 0.4947 - 2.623 0.568 - 328.1 1 2 0 0.0006 12 0 0 0 8.37E+06 6.19E+06 - - - 5.7733 0.8848 221125_WJC_METTL3_EV_vs_WT_F06.07141.07141.2 2.41 20-May K.FDNNSGQSAIK.H "sp|O75376|NCOR1_HUMAN,tr|E7EVK1|E7EVK1_HUMAN,tr|A0A088AWL3|A0A088AWL3_HUMAN" 3 1179.552 1.4 77683 7141 2 1179.550026 590.7833 Nuclear receptor corepressor 1 OS=Homo sapiens OX=9606 GN=NCOR1 PE=1 SV=2 5.84 1698.7 - 140505 - - - -1.6871 - 0.828 0.129 - 49.9 2 2 0 -0.002 11 0 0 0 1.15E+07 8.18E+06 - - - -0.6519 0.9836 221125_WJC_METTL3_EV_vs_WT_F06.07145.07145.2 0.857 12-Jun R.RSDFLQK.T sp|Q4KMQ1|TPRN_HUMAN 1 892.4767 0.89 77685 7145 2 892.477177 447.2456 Taperin OS=Homo sapiens OX=9606 GN=TPRN PE=1 SV=2 8.75 1699.3 - 2.10E+06 - - - 0.5726 - 1.262 0.079 - 217.1 1 2 0 0.0005 7 0 0 0 4.87E+07 5.47E+07 - - - 0.3616 0.9997 221125_WJC_METTL3_EV_vs_WT_F06.07149.07149.2 0.000858 14-Aug K.SC[160.03]TFDEQR[166.11].T "sp|Q96GD4|AURKB_HUMAN,tr|J3QR41|J3QR41_HUMAN,tr|J3QLN8|J3QLN8_HUMAN,tr|J3KTD6|J3KTD6_HUMAN,tr|J3KT86|J3KT86_HUMAN" 5 1051.4268 0.82 77689 7149 2 1051.429068 526.7207 Aurora kinase B OS=Homo sapiens OX=9606 GN=AURKB PE=1 SV=3 4.37 1699.5 - 864253 - - - 2.1295 - 1.756 0.533 - 322.2 1 2 0 0.0022 8 0 0 0 1.32E+07 1.62E+07 - - - 4.6751 0.9961 221125_WJC_METTL3_EV_vs_WT_F06.07157.07157.2 0.103 16-Aug R.IHC[160.03]LENVDK.A "sp|P11277|SPTB1_HUMAN,sp|O15020|SPTN2_HUMAN,sp|Q01082|SPTB2_HUMAN,tr|A4QPE4|A4QPE4_HUMAN,tr|A0A087WUZ3|A0A087WUZ3_HUMAN,tr|F8W6C1|F8W6C1_HUMAN" 6 1126.5441 999 77695 7157 2 1126.542126 564.2793 "Spectrin beta chain, erythrocytic OS=Homo sapiens OX=9606 GN=SPTB PE=1 SV=5" 5.32 1700.5 - 425116 - - - -1.7469 - 1.493 0.208 - 285.3 1 2 0 -0.002 9 0 0 0 1.96E+07 0.00E+00 - - - 1.7362 0.9992 221125_WJC_METTL3_EV_vs_WT_F06.07158.07158.2 2.81E-05 20-Nov R.EAGEQGDIEPR.R "sp|Q13283|G3BP1_HUMAN,tr|A0A7I2V5M7|A0A7I2V5M7_HUMAN,tr|A0A7I2V496|A0A7I2V496_HUMAN,tr|A0A7I2V2X7|A0A7I2V2X7_HUMAN,tr|A0A7P0P2U7|A0A7P0P2U7_HUMAN,tr|A0A7I2V548|A0A7I2V548_HUMAN,tr|A0A7I2YQN9|A0A7I2YQN9_HUMAN" 7 1199.5418 1.25 77696 7158 2 1199.54587 600.7782 Ras GTPase-activating protein-binding protein 1 OS=Homo sapiens OX=9606 GN=G3BP1 PE=1 SV=1 4 1700.6 - 383304 - - - 3.3554 - 1.905 0.538 - 446.9 1 2 0 0.004 11 0 0 0 1.17E+09 9.36E+08 - - - 4.7569 0.9999 221125_WJC_METTL3_EV_vs_WT_F06.07160.07160.2 7.18E-07 28-Oct K.VLTANSNPSSPSAAK[136.11].R sp|Q9NV56|MRGBP_HUMAN 1 1450.7507 0.96 77698 7160 2 1450.751688 726.3826 MRG\MORF4L-binding protein OS=Homo sapiens OX=9606 GN=MRGBP PE=1 SV=1 8.72 1700.9 - 314249 - - - 0.6659 - 2.453 0.572 - 236.1 1 2 0 0.001 15 0 0 0 1.92E+07 2.00E+07 - - - 5.4716 0.9998 221125_WJC_METTL3_EV_vs_WT_F06.07164.07164.2 2.19E-05 16-Sep K.DDAITAYK[136.11]K[136.11].Y "sp|Q9BY77|PDIP3_HUMAN,tr|F6VRR5|F6VRR5_HUMAN" 2 1039.5521 1.71 77700 7164 2 1039.553404 520.7833 Polymerase delta-interacting protein 3 OS=Homo sapiens OX=9606 GN=POLDIP3 PE=1 SV=2 5.96 1701.3 - 2.41E+06 - - - 1.2775 - 2.001 0.466 - 458.7 1 2 0 0.0013 9 0 0 0 2.05E+08 1.19E+08 - - - 4.4892 0.9989 221125_WJC_METTL3_EV_vs_WT_F06.07165.07165.2 0.00322 18-Jul K.AAPQSPSVPK.K "sp|O75694|NU155_HUMAN,tr|E9PF10|E9PF10_HUMAN" 2 980.5291 1.88 77701 7165 2 980.530132 491.2718 Nuclear pore complex protein Nup155 OS=Homo sapiens OX=9606 GN=NUP155 PE=1 SV=1 8.8 1701.5 - 976669 - - - 1.0576 - 1.511 0.324 - 148.8 1 2 0 0.001 10 0 0 0 7.64E+07 4.06E+07 - - - 2.5859 0.9879 221125_WJC_METTL3_EV_vs_WT_F06.07167.07167.2 0.00169 14-Aug K.VTEK[136.11]IPVR[166.11].H "sp|Q00839|HNRPU_HUMAN,tr|A0A1W2PQL0|A0A1W2PQL0_HUMAN,tr|A0A1W2PPL4|A0A1W2PPL4_HUMAN,tr|A0A1W2PQ74|A0A1W2PQ74_HUMAN,tr|Q5RI18|Q5RI18_HUMAN,tr|A0A1W2PP35|A0A1W2PP35_HUMAN,tr|A0A1W2PPS1|A0A1W2PPS1_HUMAN,tr|A0A1W2PRZ7|A0A1W2PRZ7_HUMAN,tr|A0A1W2PPH7|A0A1W2PPH7_HUMAN,tr|A0A1W2PP34|A0A1W2PP34_HUMAN,tr|A0A1X7SBS1|A0A1X7SBS1_HUMAN" 11 958.593 0.83 77703 7167 2 958.593077 480.3038 Heterogeneous nuclear ribonucleoprotein U OS=Homo sapiens OX=9606 GN=HNRNPU PE=1 SV=6 8.72 1701.7 - 686835 - - - 0.0428 - 1.924 0.173 - 236.2 1 2 1 0 8 0 0 0 1.21E+07 1.47E+07 - - - 2.2924 0.9999 221125_WJC_METTL3_EV_vs_WT_F06.07171.07171.2 4.39E-06 16-Sep K.DDAITAYKK.Y "sp|Q9BY77|PDIP3_HUMAN,tr|F6VRR5|F6VRR5_HUMAN" 2 1023.5237 1.72 77705 7171 2 1023.523568 512.7691 Polymerase delta-interacting protein 3 OS=Homo sapiens OX=9606 GN=POLDIP3 PE=1 SV=2 5.96 1702.2 - 4.31E+06 - - - -0.1055 - 1.974 0.491 - 449.4 1 2 0 -0.0001 9 0 0 0 2.05E+08 1.19E+08 - - - 4.6349 1 221125_WJC_METTL3_EV_vs_WT_F06.07172.07172.3 1.65E-05 Nov-32 R.LEC[160.03]DHC[160.03]SFR[166.11].G "sp|Q96JM3|CHAP1_HUMAN,tr|S4R3K0|S4R3K0_HUMAN,tr|A0A2R8Y735|A0A2R8Y735_HUMAN,tr|A0A2R8Y4S6|A0A2R8Y4S6_HUMAN" 4 1232.4942 0.62 77706 7172 3 1232.494286 411.8387 Chromosome alignment-maintaining phosphoprotein 1 OS=Homo sapiens OX=9606 GN=CHAMP1 PE=1 SV=2 5.32 1702.3 - 1.46E+06 - - - 0.0722 - 1.996 0.485 - 191.5 1 2 0 0.0001 9 0 0 0 3.52E+07 5.66E+07 - - - 6.0302 0.9971 221125_WJC_METTL3_EV_vs_WT_F06.07176.07176.2 0.0928 16-Sep R.RDYASEAIK.G "sp|P38646|GRP75_HUMAN,tr|H0Y8K0|H0Y8K0_HUMAN,tr|A0A7I2V2S7|A0A7I2V2S7_HUMAN,tr|A0A3B3ITI4|A0A3B3ITI4_HUMAN,tr|A0A7I2V3F7|A0A7I2V3F7_HUMAN,tr|A0A7I2YQQ5|A0A7I2YQQ5_HUMAN,tr|D6RCD7|D6RCD7_HUMAN" 7 1051.5298 8.69 77710 7176 2 1051.531046 526.7722 "Stress-70 protein, mitochondrial OS=Homo sapiens OX=9606 GN=HSPA9 PE=1 SV=2" 6.07 1702.6 - 881377 - - - 1.1621 - 1.545 0.202 - 277.6 1 2 0 0.0012 9 0 0 0 2.36E+07 2.72E+06 - - - 1.7911 0.9998 221125_WJC_METTL3_EV_vs_WT_F06.07177.07177.2 0.00273 18-Oct K.EGHGLGSLGK[136.11].G "sp|Q8IX01|SUGP2_HUMAN,tr|M0R2Z9|M0R2Z9_HUMAN" 2 961.5072 1.05 77711 7177 2 961.508188 481.7609 SURP and G-patch domain-containing protein 2 OS=Homo sapiens OX=9606 GN=SUGP2 PE=1 SV=2 6.85 1702.7 - 861511 - - - 0.9818 - 1.922 0.468 - 318.4 1 2 0 0.0009 10 0 0 0 2.30E+07 2.20E+07 - - - 4.3211 0.9995 221125_WJC_METTL3_EV_vs_WT_F06.07182.07182.2 0.00282 14-Nov R.K[136.11]WQQLQAK[136.11].R "sp|Q6P2Q9|PRP8_HUMAN,tr|I3L0J9|I3L0J9_HUMAN" 2 1044.6051 1.42 77714 7182 2 1044.60573 523.3098 Pre-mRNA-processing-splicing factor 8 OS=Homo sapiens OX=9606 GN=PRPF8 PE=1 SV=2 10 1703.3 - 1.11E+06 - - - 0.5897 - 1.826 0.303 - 401.2 1 2 0 0.0006 8 0 0 0 1.75E+07 1.23E+07 - - - 3.0948 0.9963 221125_WJC_METTL3_EV_vs_WT_F06.07185.07185.2 0.000461 18-Aug R.DVEK[136.11]GELVAK[136.11].E sp|Q8TC12|RDH11_HUMAN 1 1102.6205 0.9 77716 7185 2 1102.620361 552.3175 Retinol dehydrogenase 11 OS=Homo sapiens OX=9606 GN=RDH11 PE=1 SV=2 4.68 1703.6 - 651108 - - - -0.117 - 1.672 0.404 - 203.2 1 2 1 -0.0001 10 0 0 0 6.51E+06 7.21E+06 - - - 3.4597 0.9919 221125_WJC_METTL3_EV_vs_WT_F06.07203.07203.3 0.00984 Oct-44 K.VGGTSDVEVNEK[136.11].K "sp|P10809|CH60_HUMAN,tr|A0A7I2V2X6|A0A7I2V2X6_HUMAN,tr|A0A7I2YQK6|A0A7I2YQK6_HUMAN,tr|A0A7I2V599|A0A7I2V599_HUMAN" 4 1240.6027 1.45 77725 7203 3 1240.596609 414.5415 "60 kDa heat shock protein, mitochondrial OS=Homo sapiens OX=9606 GN=HSPD1 PE=1 SV=2" 4.14 1705.9 - 2.03E+06 - - - -4.8783 - 1.878 0.31 - 88 1 2 0 -0.0061 12 0 0 0 7.09E+07 4.88E+07 - - - 3.7414 0.9985 221125_WJC_METTL3_EV_vs_WT_F06.07212.07212.2 0.0127 16-Jun K.DVDSAYMNK.V sp|P12035|K2C3_HUMAN 1 1041.4437 1019.38 77729 7212 2 1041.442487 521.7291 "Keratin, type II cytoskeletal 3 OS=Homo sapiens OX=9606 GN=KRT3 PE=1 SV=3" 4.21 1706.9 - 5.36E+06 - - - -1.1753 - 1.069 0.411 - 75.5 1 2 0 -0.0012 9 0 0 0 1.50E+08 1.47E+05 - - - 2.2693 0.9999 221125_WJC_METTL3_EV_vs_WT_F06.07220.07220.3 2.93E-06 16/40 R.HAAC[160.03]PVLVGNK.W sp|P13674|P4HA1_HUMAN 1 1164.6074 1.7 77735 7220 3 1164.604128 389.2097 Prolyl 4-hydroxylase subunit alpha-1 OS=Homo sapiens OX=9606 GN=P4HA1 PE=1 SV=2 8.23 1707.9 - 2.78E+06 - - - -2.7778 - 2.645 0.48 - 384.8 1 2 0 -0.0032 11 0 0 0 1.45E+08 8.53E+07 - - - 6.6538 0.9992 221125_WJC_METTL3_EV_vs_WT_F06.07223.07223.3 0.00351 Dec-44 K.VGGTSDVEVNEK.K "sp|P10809|CH60_HUMAN,tr|A0A7I2V2X6|A0A7I2V2X6_HUMAN,tr|A0A7I2YQK6|A0A7I2YQK6_HUMAN,tr|A0A7I2V599|A0A7I2V599_HUMAN" 4 1232.5885 1.45 77736 7223 3 1232.586038 411.8701 "60 kDa heat shock protein, mitochondrial OS=Homo sapiens OX=9606 GN=HSPD1 PE=1 SV=2" 4.14 1708.3 - 4.18E+06 - - - -1.9658 - 2.03 0.303 - 165.8 1 2 0 -0.0024 12 0 0 0 7.09E+07 4.88E+07 - - - 3.88 0.9998 221125_WJC_METTL3_EV_vs_WT_F06.07224.07224.2 0.000184 18-Nov R.SITNTTVC[160.03]TK.C "sp|Q15637|SF01_HUMAN,tr|A0A7P0T9U7|A0A7P0T9U7_HUMAN" 2 1123.5543 1.15 77737 7224 2 1123.552728 562.7844 Splicing factor 1 OS=Homo sapiens OX=9606 GN=SF1 PE=1 SV=4 7.94 1708.4 - 1.65E+06 - - - -1.4205 - 2.162 0.482 - 280.7 1 2 0 -0.0016 10 0 0 0 3.31E+08 2.86E+08 - - - 4.7527 1 221125_WJC_METTL3_EV_vs_WT_F06.07225.07225.2 1.48E-07 18/20 R.HAAC[160.03]PVLVGNK[136.11].W sp|P13674|P4HA1_HUMAN 1 1172.6216 1.63 77738 7225 2 1172.615925 587.3181 Prolyl 4-hydroxylase subunit alpha-1 OS=Homo sapiens OX=9606 GN=P4HA1 PE=1 SV=2 8.23 1708.5 - 3.26E+06 - - - -4.808 - 3.434 0.683 - 1071.4 1 2 0 -0.0056 11 0 0 0 1.56E+08 9.54E+07 - - - 7.4214 0.9998 221125_WJC_METTL3_EV_vs_WT_F06.07235.07235.3 0.000302 Dec-36 R.LPDAHSDYAR[166.11].Y sp|Q96PK6|RBM14_HUMAN 1 1153.5392 1.89 77741 7235 3 1153.535897 385.5203 RNA-binding protein 14 OS=Homo sapiens OX=9606 GN=RBM14 PE=1 SV=2 5.21 1709.8 - 1.61E+06 - - - -2.8252 - 2.573 0.419 - 211.8 1 2 0 -0.0033 10 0 0 0 4.87E+08 2.58E+08 - - - 5.9706 0.9835 221125_WJC_METTL3_EV_vs_WT_F06.07236.07236.2 0.00102 14/18 K.FVNQLKGESR.R "sp|Q16891|MIC60_HUMAN,tr|B9A067|B9A067_HUMAN,tr|A0A087WYS0|A0A087WYS0_HUMAN,tr|C9J406|C9J406_HUMAN,tr|H7C463|H7C463_HUMAN" 5 1176.6251 1.5 77742 7236 2 1176.630243 589.3198 MICOS complex subunit MIC60 OS=Homo sapiens OX=9606 GN=IMMT PE=1 SV=1 8.75 1709.9 - 2.12E+06 - - - 4.3531 - 2.446 0.45 - 867.9 1 2 1 0.0051 10 0 0 0 7.93E+07 5.27E+07 - - - 4.8598 0.9999 221125_WJC_METTL3_EV_vs_WT_F06.07237.07237.3 5.35E-05 13/36 R.LPDAHSDYAR.Y sp|Q96PK6|RBM14_HUMAN 1 1143.5309 1.89 77743 7237 3 1143.527697 382.1842 RNA-binding protein 14 OS=Homo sapiens OX=9606 GN=RBM14 PE=1 SV=2 5.21 1710.1 - 2.02E+06 - - - -2.7887 - 2.654 0.476 - 243.3 1 2 0 -0.0032 10 0 0 0 4.79E+08 2.54E+08 - - - 6.6966 0.9999 221125_WJC_METTL3_EV_vs_WT_F06.07242.07242.2 0.000426 14/22 R.TYGEPESAGPSR[166.11].A "sp|P50402|EMD_HUMAN,tr|A0A804HIV7|A0A804HIV7_HUMAN,tr|Q5HY57|Q5HY57_HUMAN" 3 1259.5658 1.52 77745 7242 2 1259.564316 630.7902 Emerin OS=Homo sapiens OX=9606 GN=EMD PE=1 SV=1 4.53 1710.7 - 3.01E+06 - - - -1.1504 - 2.37 0.537 - 496.1 1 2 0 -0.0014 12 0 0 0 1.56E+08 1.03E+08 - - - 5.2772 0.9989 221125_WJC_METTL3_EV_vs_WT_F06.07244.07244.2 0.125 20-Nov R.NPPPNSDPNLR.R sp|Q96I24|FUBP3_HUMAN 1 1219.5945 2 77747 7244 2 1219.58991 610.8046 Far upstream element-binding protein 3 OS=Homo sapiens OX=9606 GN=FUBP3 PE=1 SV=2 5.84 1710.9 - 2.76E+06 - - - -3.8037 - 2.429 0.44 - 387.5 1 2 0 -0.0046 11 0 0 0 1.53E+08 7.66E+07 - - - 4.6902 0.9996 221125_WJC_METTL3_EV_vs_WT_F06.07248.07248.2 8.44E-06 18-Nov R.SPQDLASTSR[166.11].A "sp|Q9HC52|CBX8_HUMAN,tr|C9J6K3|C9J6K3_HUMAN,tr|C9JM54|C9JM54_HUMAN" 3 1070.5232 2.56 77749 7248 2 1070.525691 536.2689 Chromobox protein homolog 8 OS=Homo sapiens OX=9606 GN=CBX8 PE=1 SV=3 5.55 1711.4 - 1.32E+06 - - - 2.3531 - 2.098 0.509 - 496.1 1 2 0 0.0025 10 0 0 0 8.03E+07 3.14E+07 - - - 4.868 0.9994 221125_WJC_METTL3_EV_vs_WT_F06.07253.07253.2 0.0203 18-Nov R.SITNTTVC[160.03]TK[136.11].C "sp|Q15637|SF01_HUMAN,tr|A0A7P0T9U7|A0A7P0T9U7_HUMAN" 2 1131.5685 1.16 77750 7253 2 1131.56701 566.7915 Splicing factor 1 OS=Homo sapiens OX=9606 GN=SF1 PE=1 SV=4 7.94 1712.2 - 1.43E+07 - - - -1.338 - 2.073 0.286 - 340.9 1 2 0 -0.0015 10 0 0 0 3.31E+08 2.86E+08 - - - 3.1878 0.9997 221125_WJC_METTL3_EV_vs_WT_F06.07254.07254.3 0.00141 13/48 R.ELQHAALGGTATR.Q sp|O14828|SCAM3_HUMAN 1 1323.6895 1.2 77751 7254 3 1323.687824 442.2371 Secretory carrier-associated membrane protein 3 OS=Homo sapiens OX=9606 GN=SCAMP3 PE=1 SV=3 6.85 1712.3 - 3.03E+06 - - - -1.2752 - 2.338 0.313 - 252.2 1 2 0 -0.0017 13 0 0 0 1.52E+08 1.27E+08 - - - 4.3319 0.9983 221125_WJC_METTL3_EV_vs_WT_F06.07255.07255.2 0.0071 12-Jun K.YYLHDDR.E "sp|Q9Y2W1|TR150_HUMAN,tr|A0A3B3ITZ9|A0A3B3ITZ9_HUMAN" 2 980.4352 1.7 77752 7255 2 980.433246 491.2249 Thyroid hormone receptor-associated protein 3 OS=Homo sapiens OX=9606 GN=THRAP3 PE=1 SV=2 5.21 1712.4 - 2.08E+06 - - - -1.9879 - 1.446 0.318 - 164 1 2 0 -0.0019 7 0 0 0 7.61E+07 4.47E+07 - - - 2.5577 0.9904 221125_WJC_METTL3_EV_vs_WT_F06.07264.07264.2 0.0126 16-Oct L.PDAHSDYAR.Y sp|Q96PK6|RBM14_HUMAN 1 1030.4468 2.05 77759 7264 2 1030.445468 516.2307 RNA-binding protein 14 OS=Homo sapiens OX=9606 GN=RBM14 PE=1 SV=2 5.22 1713.5 - 1.07E+06 - - - -1.314 - 2.076 0.513 - 474.1 1 1 0 -0.0014 9 0 0 0 5.23E+07 2.55E+07 - - - 4.9428 0.9982 221125_WJC_METTL3_EV_vs_WT_F06.07265.07265.2 0.000104 13/18 R.LPDAHSDYAR[166.11].Y sp|Q96PK6|RBM14_HUMAN 1 1153.5392 2.1 77760 7265 2 1153.53335 577.7769 RNA-binding protein 14 OS=Homo sapiens OX=9606 GN=RBM14 PE=1 SV=2 5.21 1713.6 - 907356 - - - -5.0332 - 2.366 0.547 - 823.9 1 2 0 -0.0058 10 0 0 0 6.83E+07 3.26E+07 - - - 5.4832 1 221125_WJC_METTL3_EV_vs_WT_F06.07270.07270.2 5.00E-07 22-Dec R.TYGEPESAGPSR.A "sp|P50402|EMD_HUMAN,tr|A0A804HIV7|A0A804HIV7_HUMAN,tr|Q5HY57|Q5HY57_HUMAN" 3 1249.5575 1.51 77763 7270 2 1249.555573 625.786 Emerin OS=Homo sapiens OX=9606 GN=EMD PE=1 SV=1 4.53 1714.2 - 7.17E+06 - - - -1.5381 - 2.187 0.639 - 376.8 1 2 0 -0.0019 12 0 0 0 1.54E+08 1.02E+08 - - - 5.819 0.9999 221125_WJC_METTL3_EV_vs_WT_F06.07271.07271.3 0.00304 Nov-36 R.EFARPEDC[160.03]PR.A sp|Q5JSZ5|PRC2B_HUMAN 1 1275.5666 1.82 77764 7271 3 1275.566616 426.1961 Protein PRRC2B OS=Homo sapiens OX=9606 GN=PRRC2B PE=1 SV=2 4.68 1714.3 - 2.52E+06 - - - -0.0031 - 2.039 0.459 - 226.2 1 2 0 0 10 0 0 0 1.18E+08 6.50E+07 - - - 5.7381 0.9998 221125_WJC_METTL3_EV_vs_WT_F06.07273.07273.2 2.15E-06 15/24 R.ELQHAALGGTATR.Q sp|O14828|SCAM3_HUMAN 1 1323.6895 1.07 77766 7273 2 1323.686749 662.852 Secretory carrier-associated membrane protein 3 OS=Homo sapiens OX=9606 GN=SCAMP3 PE=1 SV=3 6.85 1714.5 - 1.18E+06 - - - -2.0873 - 2.766 0.513 - 857.5 1 2 0 -0.0028 13 0 0 0 2.27E+07 2.11E+07 - - - 5.4403 0.9992 221125_WJC_METTL3_EV_vs_WT_F06.07274.07274.2 0.00432 20-Nov K.IANLGSC[160.03]NDSK.L sp|Q9HCY8|S10AE_HUMAN 1 1177.5397 38.97 77767 7274 2 1177.54366 589.7771 Protein S100-A14 OS=Homo sapiens OX=9606 GN=S100A14 PE=1 SV=1 5.83 1714.6 - 1.16E+06 - - - 3.3315 - 2.359 0.443 - 350.5 1 2 0 0.0039 11 0 0 0 7.22E+07 1.85E+06 - - - 4.6335 1 221125_WJC_METTL3_EV_vs_WT_F06.07275.07275.2 1.62E-06 14/24 R.ELQHAALGGTATR[166.11].Q sp|O14828|SCAM3_HUMAN 1 1333.6978 1.07 77768 7275 2 1333.698494 667.8562 Secretory carrier-associated membrane protein 3 OS=Homo sapiens OX=9606 GN=SCAMP3 PE=1 SV=3 6.85 1714.8 - 1.02E+06 - - - 0.5339 - 2.787 0.56 - 746 1 2 0 0.0007 13 0 0 0 2.27E+07 2.11E+07 - - - 5.8075 0.8389 221125_WJC_METTL3_EV_vs_WT_F06.07278.07278.2 0.232 14-Jul R.DK[136.11]MEDIER[166.11].Q sp|Q9UQE7|SMC3_HUMAN 1 1052.4927 0.28 77771 7278 2 1052.491784 527.2536 Structural maintenance of chromosomes protein 3 OS=Homo sapiens OX=9606 GN=SMC3 PE=1 SV=2 4.32 1715.2 - 731920 - - - -0.8988 - 1.542 0.002 - 191.9 1 2 1 -0.0009 8 0 0 0 1.35E+07 4.76E+07 - - - 0.3616 1 221125_WJC_METTL3_EV_vs_WT_F06.07283.07283.3 2.73E-05 Dec-40 K.VEETTEHLVTK.S "sp|P52732|KIF11_HUMAN,tr|A0A7I2V3A9|A0A7I2V3A9_HUMAN" 2 1284.6561 4.5 77774 7283 3 1284.656553 429.226 Kinesin-like protein KIF11 OS=Homo sapiens OX=9606 GN=KIF11 PE=1 SV=2 4.75 1715.8 - 3.00E+07 - - - 0.3168 - 2.484 0.486 - 267.3 1 2 0 0.0004 11 0 0 0 4.23E+08 9.41E+07 - - - 6.5431 0.9997 221125_WJC_METTL3_EV_vs_WT_F06.07284.07284.3 0.00118 Nov-48 R.ELQHAALGGTATR[166.11].Q sp|O14828|SCAM3_HUMAN 1 1333.6978 1.2 77775 7284 3 1333.697308 445.5732 Secretory carrier-associated membrane protein 3 OS=Homo sapiens OX=9606 GN=SCAMP3 PE=1 SV=3 6.85 1715.9 - 8.39E+06 - - - -0.3554 - 1.999 0.35 - 193.4 1 2 0 -0.0005 13 0 0 0 1.52E+08 1.27E+08 - - - 4.32 0.9999 221125_WJC_METTL3_EV_vs_WT_F06.07285.07285.2 5.40E-06 20-Nov K.VEETTEHLVTK.S "sp|P52732|KIF11_HUMAN,tr|A0A7I2V3A9|A0A7I2V3A9_HUMAN" 2 1284.6561 5.35 77776 7285 2 1284.655822 643.3353 Kinesin-like protein KIF11 OS=Homo sapiens OX=9606 GN=KIF11 PE=1 SV=2 4.75 1715.9 - 4.51E+06 - - - -0.2522 - 2.571 0.549 - 381.4 1 2 0 -0.0003 11 0 0 0 6.75E+07 1.26E+07 - - - 5.6504 0.9996 221125_WJC_METTL3_EV_vs_WT_F06.07286.07286.3 0.00834 Nov-36 K.K[136.11]SLDQDPVVR[166.11].A "sp|Q92598|HS105_HUMAN,tr|Q5TBM3|Q5TBM3_HUMAN,tr|A0A0A0MSM0|A0A0A0MSM0_HUMAN" 3 1173.6473 0.29 77777 7286 3 1173.650902 392.223 Heat shock protein 105 kDa OS=Homo sapiens OX=9606 GN=HSPH1 PE=1 SV=1 5.96 1716 - 3.67E+06 - - - 3.1057 - 2.286 0.374 - 276.3 1 2 0 0.0036 10 0 0 0 5.68E+07 1.96E+08 - - - 5.1233 0.9999 221125_WJC_METTL3_EV_vs_WT_F06.07287.07287.3 2.07E-05 16/52 R.ALAAPAAEEKEEAR.E sp|Q01650|LAT1_HUMAN 1 1454.7365 1.43 77778 7287 3 1454.737023 485.9195 Large neutral amino acids transporter small subunit 1 OS=Homo sapiens OX=9606 GN=SLC7A5 PE=1 SV=2 4.49 1716 - 3.31E+06 - - - 0.3444 - 2.806 0.488 - 383.5 1 2 1 0.0005 14 0 0 0 1.30E+08 9.08E+07 - - - 6.7225 0.8367 221125_WJC_METTL3_EV_vs_WT_F06.07296.07296.2 0.121 22-Oct L.AAPAAEEKEEAR.E sp|Q01650|LAT1_HUMAN 1 1270.6153 2.58 77785 7296 2 1270.613962 636.3149 Large neutral amino acids transporter small subunit 1 OS=Homo sapiens OX=9606 GN=SLC7A5 PE=1 SV=2 4.49 1717.1 - 403337 - - - -1.0877 - 2.102 0.391 - 198.2 1 1 1 -0.0014 12 0 0 0 9.20E+06 3.56E+06 - - - 3.8832 0.9918 221125_WJC_METTL3_EV_vs_WT_F06.07299.07299.2 0.00106 26-Oct R.ALAAPAAEEKEEAR.E sp|Q01650|LAT1_HUMAN 1 1454.7365 1.59 77788 7299 2 1454.738856 728.3755 Large neutral amino acids transporter small subunit 1 OS=Homo sapiens OX=9606 GN=SLC7A5 PE=1 SV=2 4.49 1717.4 - 267544 - - - 1.6044 - 1.904 0.35 - 266.8 1 2 1 0.0023 14 0 0 0 7.22E+06 4.55E+06 - - - 3.2413 1 221125_WJC_METTL3_EV_vs_WT_F06.07300.07300.2 2.02E-07 26-Dec K.FQGSGAATETAESR[166.11].R "sp|O15047|SET1A_HUMAN,tr|A0A804HLA6|A0A804HLA6_HUMAN" 2 1420.6458 1.14 77789 7300 2 1420.646678 711.3302 Histone-lysine N-methyltransferase SETD1A OS=Homo sapiens OX=9606 GN=SETD1A PE=1 SV=3 4.53 1717.6 - 182818 - - - 0.6138 - 2.476 0.654 - 332.6 1 2 0 0.0009 14 0 0 0 9.61E+06 8.46E+06 - - - 6.1463 0.995 221125_WJC_METTL3_EV_vs_WT_F06.07301.07301.2 0.0041 26-Nov R.ALAAPAAEEK[136.11]EEAR[166.11].E sp|Q01650|LAT1_HUMAN 1 1472.759 1.59 77790 7301 2 1472.760289 737.3868 Large neutral amino acids transporter small subunit 1 OS=Homo sapiens OX=9606 GN=SLC7A5 PE=1 SV=2 4.49 1717.7 - 147017 - - - 0.8807 - 2.14 0.328 - 342.5 1 2 1 0.0013 14 0 0 0 7.22E+06 4.55E+06 - - - 3.3724 0.9999 221125_WJC_METTL3_EV_vs_WT_F06.07304.07304.2 0.000104 13/18 R.LPDAHSDYAR.Y sp|Q96PK6|RBM14_HUMAN 1 1143.5309 2.1 77792 7304 2 1143.532071 572.7727 RNA-binding protein 14 OS=Homo sapiens OX=9606 GN=RBM14 PE=1 SV=2 5.21 1718 - 3.56E+06 - - - 1.0363 - 2.301 0.526 - 735 1 2 0 0.0012 10 0 0 0 6.83E+07 3.26E+07 - - - 5.2518 0.9998 221125_WJC_METTL3_EV_vs_WT_F06.07305.07305.3 0.00371 20/52 R.ALAAPAAEEK[136.11]EEAR[166.11].E sp|Q01650|LAT1_HUMAN 1 1472.759 1.44 77793 7305 3 1472.758412 491.9269 Large neutral amino acids transporter small subunit 1 OS=Homo sapiens OX=9606 GN=SLC7A5 PE=1 SV=2 4.49 1718 - 5.59E+06 - - - -0.3938 - 2.775 0.452 - 658.1 1 2 1 -0.0006 14 0 0 0 1.31E+08 9.08E+07 - - - 6.2916 0.9999 221125_WJC_METTL3_EV_vs_WT_F06.07306.07306.3 0.00102 Nov-40 K.VEETTEHLVTK[136.11].S "sp|P52732|KIF11_HUMAN,tr|A0A7I2V3A9|A0A7I2V3A9_HUMAN" 2 1292.6703 4.5 77794 7306 3 1292.670994 431.8974 Kinesin-like protein KIF11 OS=Homo sapiens OX=9606 GN=KIF11 PE=1 SV=2 4.75 1718.1 - 4.83E+06 - - - 0.5013 - 2.22 0.388 - 207.4 1 2 0 0.0006 11 0 0 0 4.23E+08 9.41E+07 - - - 5.1312 0.9998 221125_WJC_METTL3_EV_vs_WT_F06.07309.07309.2 0.00109 20-Dec K.VEETTEHLVTK[136.11].S "sp|P52732|KIF11_HUMAN,tr|A0A7I2V3A9|A0A7I2V3A9_HUMAN" 2 1292.6703 5.35 77797 7309 2 1292.672137 647.3424 Kinesin-like protein KIF11 OS=Homo sapiens OX=9606 GN=KIF11 PE=1 SV=2 4.75 1718.4 - 707710 - - - 1.3855 - 2.49 0.469 - 566.5 1 2 0 0.0018 11 0 0 0 6.75E+07 1.26E+07 - - - 4.9724 0.9999 221125_WJC_METTL3_EV_vs_WT_F06.07311.07311.2 1.48E-07 26-Oct K.FQGSGAATETAESR.R "sp|O15047|SET1A_HUMAN,tr|A0A804HLA6|A0A804HLA6_HUMAN" 2 1410.6375 1.14 77799 7311 2 1410.638826 706.326 Histone-lysine N-methyltransferase SETD1A OS=Homo sapiens OX=9606 GN=SETD1A PE=1 SV=3 4.53 1718.7 - 299469 - - - 0.9145 - 2.152 0.545 - 245 1 2 0 0.0013 14 0 0 0 9.61E+06 8.46E+06 - - - 4.9892 1 221125_WJC_METTL3_EV_vs_WT_F06.07315.07315.2 5.70E-08 13/24 R.DTPAAVTAEGSGK.Y "sp|Q86UP3|ZFHX4_HUMAN,tr|A0A494BZV7|A0A494BZV7_HUMAN,tr|E5RI93|E5RI93_HUMAN,tr|E7EVZ1|E7EVZ1_HUMAN" 4 1202.5779 3.17 77801 7315 2 1202.58408 602.2962 Zinc finger homeobox protein 4 OS=Homo sapiens OX=9606 GN=ZFHX4 PE=1 SV=1 4.37 1719.1 - 767726 - - - 5.1423 - 2.336 0.637 - 581.8 1 2 0 0.0062 13 0 0 0 1.83E+07 5.77E+06 - - - 5.9215 0.9972 221125_WJC_METTL3_EV_vs_WT_F06.07316.07316.2 0.000227 18-Oct R.SPQDLASTSR.A "sp|Q9HC52|CBX8_HUMAN,tr|C9J6K3|C9J6K3_HUMAN,tr|C9JM54|C9JM54_HUMAN" 3 1060.5149 2.56 77802 7316 2 1060.519717 531.2647 Chromobox protein homolog 8 OS=Homo sapiens OX=9606 GN=CBX8 PE=1 SV=3 5.55 1719.2 - 687493 - - - 4.5402 - 1.976 0.431 - 417.2 1 2 0 0.0048 10 0 0 0 8.03E+07 3.14E+07 - - - 4.1239 0.9999 221125_WJC_METTL3_EV_vs_WT_F06.07320.07320.3 0.00114 Oct-36 R.EFAR[166.11]PEDC[160.03]PR[166.11].A sp|Q5JSZ5|PRC2B_HUMAN 1 1295.5832 1.81 77804 7320 3 1295.583684 432.8683 Protein PRRC2B OS=Homo sapiens OX=9606 GN=PRRC2B PE=1 SV=2 4.68 1719.7 - 3.03E+06 - - - 0.4045 - 2.004 0.412 - 205.9 1 2 0 0.0005 10 0 0 0 1.17E+08 6.45E+07 - - - 5.1634 0.9985 221125_WJC_METTL3_EV_vs_WT_F06.07321.07321.3 0.0118 Oct-44 K.SKAEAESLYQSK.Y sp|P04264|K2C1_HUMAN 1 1339.662 22.76 77805 7321 3 1339.661495 447.5613 "Keratin, type II cytoskeletal 1 OS=Homo sapiens OX=9606 GN=KRT1 PE=1 SV=6" 5.86 1719.8 - 1.04E+06 - - - -0.3471 - 1.945 0.337 - 115.9 1 2 1 -0.0005 12 0 0 0 1.91E+07 8.39E+05 - - - 4.1411 0.877 221125_WJC_METTL3_EV_vs_WT_F06.07323.07323.2 0.0769 18-Aug R.EFARPEDC[160.03]PR.A sp|Q5JSZ5|PRC2B_HUMAN 1 1275.5666 0.2 77807 7323 2 1275.577735 638.7906 Protein PRRC2B OS=Homo sapiens OX=9606 GN=PRRC2B PE=1 SV=2 4.68 1720 - 330730 - - - 8.7138 - 1.662 0.246 - 129.4 1 2 0 0.0111 10 0 0 0 5.16E+06 2.64E+07 - - - 2.2725 0.7862 221125_WJC_METTL3_EV_vs_WT_F06.07325.07325.2 11.6 16-Jul K.YLHPPPHLK[136.11].T "sp|Q9NR56|MBNL1_HUMAN,sp|Q9NUK0|MBNL3_HUMAN,tr|H7C4T5|H7C4T5_HUMAN,tr|Q86VM6|Q86VM6_HUMAN,tr|C9J4T8|C9J4T8_HUMAN,tr|A0A0A0MQX8|A0A0A0MQX8_HUMAN,tr|B1AKI6|B1AKI6_HUMAN,tr|C9JP00|C9JP00_HUMAN" 8 1108.6273 1.68 77809 7325 2 1108.624023 555.3209 Muscleblind-like protein 1 OS=Homo sapiens OX=9606 GN=MBNL1 PE=1 SV=2 8.61 1720.3 - 284924 - - - -2.9559 - 1.2 0.003 - 146.5 2 2 0 -0.0033 9 0 0 0 1.45E+07 8.63E+06 - - - -0.5449 0.9994 221125_WJC_METTL3_EV_vs_WT_F06.07329.07329.3 0.00402 Sep-44 R.ALADHSMAQTPR[166.11].L sp|P08240|SRPRA_HUMAN 1 1306.6327 0.95 77812 7329 3 1306.634743 436.5515 Signal recognition particle receptor subunit alpha OS=Homo sapiens OX=9606 GN=SRPRA PE=1 SV=2 6.79 1720.8 - 1.01E+06 - - - 1.5337 - 1.829 0.338 - 126.5 1 2 0 0.002 12 0 0 0 1.37E+07 1.45E+07 - - - 3.9814 0.9848 221125_WJC_METTL3_EV_vs_WT_F06.07331.07331.2 3.13E-06 16-Oct F.VHVTDLSGK.E "sp|P62263|RS14_HUMAN,tr|A0A2R8Y811|A0A2R8Y811_HUMAN,tr|E5RH77|E5RH77_HUMAN" 3 954.5134 1.25 77813 7331 2 954.514641 478.264 40S ribosomal protein S14 OS=Homo sapiens OX=9606 GN=RPS14 PE=1 SV=3 6.71 1721 - 1.98E+06 - - - 1.253 - 1.962 0.448 - 444.5 1 1 0 0.0012 9 0 0 0 3.59E+07 2.87E+07 - - - 4.2994 0.9931 221125_WJC_METTL3_EV_vs_WT_F06.07332.07332.2 0.216 18-Jun R.RISAVSVAQR.V "sp|Q7L2E3|DHX30_HUMAN,tr|H7BXY3|H7BXY3_HUMAN" 2 1085.6305 0.95 77814 7332 2 1085.631404 543.8225 ATP-dependent RNA helicase DHX30 OS=Homo sapiens OX=9606 GN=DHX30 PE=1 SV=1 12 1721.1 - 443092 - - - 0.7949 - 1.319 0.198 - 50.2 4 2 0 0.0009 10 0 0 0 1.05E+07 1.10E+07 - - - 1.0071 0.9984 221125_WJC_METTL3_EV_vs_WT_F06.07333.07333.2 0.0886 16-Sep K.DTDSEEEIR.E "sp|P0DP25|CALM3_HUMAN,sp|P0DP23|CALM1_HUMAN,sp|P0DP24|CALM2_HUMAN,tr|G3V361|G3V361_HUMAN,tr|A0A590UJI2|A0A590UJI2_HUMAN,tr|Q96HY3|Q96HY3_HUMAN,tr|A0A590UJC0|A0A590UJC0_HUMAN,tr|G3V226|G3V226_HUMAN,tr|E7EMB3|E7EMB3_HUMAN" 9 1092.4571 1.31 77815 7333 2 1092.458741 547.2358 Calmodulin-3 OS=Homo sapiens OX=9606 GN=CALM3 PE=1 SV=1 3.83 1721.3 - 322426 - - - 1.4911 - 1.915 0.204 - 480.5 1 2 0 0.0016 9 0 0 0 3.62E+07 2.76E+07 - - - 2.4269 0.9998 221125_WJC_METTL3_EV_vs_WT_F06.07334.07334.2 4.06E-06 30-Nov R.ASAAEGVGEPGASAGR[166.11].A "tr|A0A7I2V3I7|A0A7I2V3I7_HUMAN,tr|A0A7I2YQQ9|A0A7I2YQQ9_HUMAN,tr|A0A499FIZ0|A0A499FIZ0_HUMAN" 3 1395.6618 0.85 77816 7334 2 1395.663634 698.8382 WD repeat-containing protein 26 OS=Homo sapiens OX=9606 GN=WDR26 PE=1 SV=1 4.53 1721.4 - 267541 - - - 1.3205 - 2.257 0.544 - 299.8 1 2 0 0.0018 16 0 0 0 3.48E+06 4.10E+06 - - - 5.0598 0.9998 221125_WJC_METTL3_EV_vs_WT_F06.07344.07344.2 2.36E-05 20-Dec K.LSSDVC[160.03]PTSDK.S "sp|P11717|MPRI_HUMAN,tr|A0A7I2V381|A0A7I2V381_HUMAN" 2 1207.5391 1.85 77824 7344 2 1207.540525 604.7768 Cation-independent mannose-6-phosphate receptor OS=Homo sapiens OX=9606 GN=IGF2R PE=1 SV=3 4.21 1722.5 - 429622 - - - 1.2066 - 2.441 0.434 - 474.4 1 2 0 0.0015 11 0 0 0 1.63E+07 8.82E+06 - - - 4.6602 0.9566 221125_WJC_METTL3_EV_vs_WT_F06.07345.07345.2 0.362 16-Aug R.DKLC[160.03]GPYEK.F "sp|Q92598|HS105_HUMAN,tr|A0A0A0MSM0|A0A0A0MSM0_HUMAN" 2 1108.5223 0.04 77825 7345 2 1108.520631 555.2684 Heat shock protein 105 kDa OS=Homo sapiens OX=9606 GN=HSPH1 PE=1 SV=1 6.06 1722.6 - 421804 - - - -1.502 - 1.304 0.241 - 179.6 1 2 1 -0.0017 9 0 0 0 6.38E+06 1.47E+08 - - - 1.5884 1 221125_WJC_METTL3_EV_vs_WT_F06.07347.07347.2 7.82E-07 13/22 K.VGGTSDVEVNEK[136.11].K "sp|P10809|CH60_HUMAN,tr|A0A7I2V2X6|A0A7I2V2X6_HUMAN,tr|A0A7I2YQK6|A0A7I2YQK6_HUMAN,tr|A0A7I2V599|A0A7I2V599_HUMAN" 4 1240.6027 1.36 77826 7347 2 1240.603923 621.3086 "60 kDa heat shock protein, mitochondrial OS=Homo sapiens OX=9606 GN=HSPD1 PE=1 SV=2" 4.14 1722.8 - 6.31E+06 - - - 1.0172 - 2.873 0.585 - 811.3 1 2 0 0.0013 12 0 0 0 2.35E+08 1.73E+08 - - - 6.1382 0.9996 221125_WJC_METTL3_EV_vs_WT_F06.07349.07349.2 0.000666 13/18 K.K[136.11]SLDQDPVVR[166.11].A "sp|Q92598|HS105_HUMAN,tr|Q5TBM3|Q5TBM3_HUMAN,tr|A0A0A0MSM0|A0A0A0MSM0_HUMAN" 3 1173.6473 0.11 77827 7349 2 1173.649085 587.8309 Heat shock protein 105 kDa OS=Homo sapiens OX=9606 GN=HSPH1 PE=1 SV=1 5.96 1723.1 - 2.64E+06 - - - 1.5575 - 2.533 0.317 - 606.2 1 2 0 0.0018 10 0 0 0 5.51E+06 5.06E+07 - - - 3.976 0.9997 221125_WJC_METTL3_EV_vs_WT_F06.07350.07350.2 2.71E-05 22-Dec K.LYTSAPNTSQGK[136.11].D "sp|Q5QJE6|TDIF2_HUMAN,tr|J3KP30|J3KP30_HUMAN" 2 1273.6394 1.1 77828 7350 2 1273.641793 637.827 Deoxynucleotidyltransferase terminal-interacting protein 2 OS=Homo sapiens OX=9606 GN=DNTTIP2 PE=1 SV=2 8.59 1723.2 - 712618 - - - 1.8938 - 1.985 0.547 - 405.7 1 2 0 0.0024 12 0 0 0 1.67E+07 1.52E+07 - - - 4.8844 0.9465 221125_WJC_METTL3_EV_vs_WT_F06.07351.07351.2 8.35E-06 16-Sep F.VHVTDLSGK[136.11].E "sp|P62263|RS14_HUMAN,tr|A0A2R8Y811|A0A2R8Y811_HUMAN,tr|E5RH77|E5RH77_HUMAN" 3 962.5276 1.33 77829 7351 2 962.530925 482.2711 40S ribosomal protein S14 OS=Homo sapiens OX=9606 GN=RPS14 PE=1 SV=3 6.71 1723.2 - 1.72E+06 - - - 3.4077 - 1.797 0.506 - 321.1 1 1 0 0.0033 9 0 0 0 3.57E+07 2.69E+07 - - - 4.473 0.9999 221125_WJC_METTL3_EV_vs_WT_F06.07355.07355.2 2.08E-06 26-Oct R.AEAGSQTAAGAMER[166.11].A "sp|Q6L8Q7|PDE12_HUMAN,tr|F6T1Q0|F6T1Q0_HUMAN" 2 1358.6124 0.67 77833 7355 2 1358.613015 680.3135 "2',5'-phosphodiesterase 12 OS=Homo sapiens OX=9606 GN=PDE12 PE=1 SV=2" 4.53 1723.7 - 212875 - - - 0.4541 - 2.714 0.476 - 369.8 1 2 0 0.0006 14 0 0 0 1.29E+06 1.94E+06 - - - 5.062 0.9999 221125_WJC_METTL3_EV_vs_WT_F06.07358.07358.3 7.51E-06 Nov-40 R.KVVGC[160.03]SC[160.03]VVVK.D sp|P25398|RS12_HUMAN 1 1233.6573 1.76 77834 7358 3 1233.659059 412.2264 40S ribosomal protein S12 OS=Homo sapiens OX=9606 GN=RPS12 PE=1 SV=3 8.9 1724.1 - 3.71E+06 - - - 1.3853 - 2.652 0.437 - 246.9 1 2 0 0.0017 11 0 0 0 1.89E+09 1.07E+09 - - - 6.1823 0.9945 221125_WJC_METTL3_EV_vs_WT_F06.07359.07359.2 0.478 16-Sep K.DTDSEEEIR[166.11].E "sp|P0DP25|CALM3_HUMAN,sp|P0DP23|CALM1_HUMAN,sp|P0DP24|CALM2_HUMAN,tr|G3V361|G3V361_HUMAN,tr|A0A590UJI2|A0A590UJI2_HUMAN,tr|Q96HY3|Q96HY3_HUMAN,tr|A0A590UJC0|A0A590UJC0_HUMAN,tr|G3V226|G3V226_HUMAN,tr|E7EMB3|E7EMB3_HUMAN" 9 1102.4654 1.31 77835 7359 2 1102.469102 552.24 Calmodulin-3 OS=Homo sapiens OX=9606 GN=CALM3 PE=1 SV=1 3.83 1724.1 - 1.46E+06 - - - 3.3743 - 1.703 0.252 - 284.5 1 2 0 0.0037 9 0 0 0 3.60E+07 2.76E+07 - - - 2.4413 1 221125_WJC_METTL3_EV_vs_WT_F06.07360.07360.2 2.02E-06 15/20 R.K[136.11]VVGC[160.03]SC[160.03]VVVK[136.11].D sp|P25398|RS12_HUMAN 1 1249.6858 1.83 77836 7360 2 1249.688836 625.8502 40S ribosomal protein S12 OS=Homo sapiens OX=9606 GN=RPS12 PE=1 SV=3 8.9 1724.2 - 928036 - - - 2.4694 - 2.826 0.624 - 694.4 1 2 0 0.0031 11 0 0 0 8.71E+08 4.76E+08 - - - 6.4593 0.9714 221125_WJC_METTL3_EV_vs_WT_F06.07361.07361.2 3.36E-05 22-Nov K.MTGSNTEEIDSR[166.11].L "sp|Q8N573|OXR1_HUMAN,tr|H0YC07|H0YC07_HUMAN" 2 1348.5804 0.93 77837 7361 2 1348.589844 675.2975 Oxidation resistance protein 1 OS=Homo sapiens OX=9606 GN=OXR1 PE=1 SV=2 4.14 1724.4 - 241271 - - - 6.9814 - 1.975 0.32 - 370.6 1 2 0 0.0094 12 0 0 0 3.48E+06 3.72E+06 - - - 3.1923 0.9998 221125_WJC_METTL3_EV_vs_WT_F06.07362.07362.2 0.000519 22-Nov R.LSTASEETVQNR[166.11].V "sp|O43379|WDR62_HUMAN,tr|A0A7P0T9T4|A0A7P0T9T4_HUMAN,tr|A0A7P0T8U8|A0A7P0T8U8_HUMAN,tr|A0A7P0T972|A0A7P0T972_HUMAN,tr|A0A7P0T8R7|A0A7P0T8R7_HUMAN,tr|A0A7P0T9T7|A0A7P0T9T7_HUMAN,tr|A0A7P0TAH3|A0A7P0TAH3_HUMAN,tr|A0A7P0TAK3|A0A7P0TAK3_HUMAN,tr|A0A7P0T9G3|A0A7P0T9G3_HUMAN,tr|A0A2R8YD43|A0A2R8YD43_HUMAN,tr|A0A7P0T9D9|A0A7P0T9D9_HUMAN,tr|A0A7P0T9F6|A0A7P0T9F6_HUMAN,tr|A0A7P0TBE7|A0A7P0TBE7_HUMAN,tr|A0A7P0Z436|A0A7P0Z436_HUMAN,tr|H7C3R4|H7C3R4_HUMAN" 15 1343.6556 0.58 77838 7362 2 1343.657231 672.8351 WD repeat-containing protein 62 OS=Homo sapiens OX=9606 GN=WDR62 PE=1 SV=4 4.53 1724.5 - 238128 - - - 1.1819 - 2.475 0.492 - 486.7 1 2 0 0.0016 12 0 0 0 1.78E+06 3.09E+06 - - - 5.0589 0.9998 221125_WJC_METTL3_EV_vs_WT_F06.07364.07364.2 0.000432 20-Jun K.C[160.03]NTC[160.03]GEPITDR.M "sp|Q15942|ZYX_HUMAN,tr|H0Y2Y8|H0Y2Y8_HUMAN,tr|C9JJK5|C9JJK5_HUMAN" 3 1321.5391 4.72 77840 7364 2 1321.54048 661.7768 Zyxin OS=Homo sapiens OX=9606 GN=ZYX PE=1 SV=1 4.37 1724.8 - 130202 - - - 1.0556 - 1.377 0.591 - 102 1 2 0 0.0014 11 0 0 0 9.69E+07 2.05E+07 - - - 4.2711 1 221125_WJC_METTL3_EV_vs_WT_F06.07368.07368.3 4.23E-08 14/40 R.K[136.11]VVGC[160.03]SC[160.03]VVVK[136.11].D sp|P25398|RS12_HUMAN 1 1249.6858 1.77 77842 7368 3 1249.688838 417.5692 40S ribosomal protein S12 OS=Homo sapiens OX=9606 GN=RPS12 PE=1 SV=3 8.9 1725.2 - 9.52E+06 - - - 2.471 - 3.152 0.612 - 487 1 2 0 0.0031 11 0 0 0 1.90E+09 1.07E+09 - - - 8.6237 0.9994 221125_WJC_METTL3_EV_vs_WT_F06.07372.07372.2 0.0116 16-Aug R.QITAQQINK.L sp|Q92900|RENT1_HUMAN 1 1042.5771 1.21 77846 7372 2 1042.578106 522.2958 Regulator of nonsense transcripts 1 OS=Homo sapiens OX=9606 GN=UPF1 PE=1 SV=2 8.75 1725.5 - 866733 - - - 0.9572 - 1.495 0.394 - 198.5 1 2 0 0.001 9 0 0 0 1.01E+07 8.32E+06 - - - 3.1141 0.9909 221125_WJC_METTL3_EV_vs_WT_F06.07374.07374.2 0.415 16-Nov K.R[166.11]TTVVAQLK[136.11].Q "sp|P60228|EIF3E_HUMAN,tr|A0A7I2V3I2|A0A7I2V3I2_HUMAN,tr|A0A7I2V570|A0A7I2V570_HUMAN,tr|A0A7I2V2Q9|A0A7I2V2Q9_HUMAN,tr|H0YBP5|H0YBP5_HUMAN,tr|A0A7I2V5Z6|A0A7I2V5Z6_HUMAN,tr|A0A7I2V2H9|A0A7I2V2H9_HUMAN,tr|B3KW56|B3KW56_HUMAN,tr|A0A7I2V4B4|A0A7I2V4B4_HUMAN,tr|A0A7I2V3I0|A0A7I2V3I0_HUMAN,tr|A0A7I2V3S3|A0A7I2V3S3_HUMAN,tr|A0A7I2V4G3|A0A7I2V4G3_HUMAN,tr|A0A7I2V3W9|A0A7I2V3W9_HUMAN,tr|H0YBR5|H0YBR5_HUMAN,tr|A0A7I2V429|A0A7I2V429_HUMAN,tr|A0A7I2V2W0|A0A7I2V2W0_HUMAN,tr|A0A161SXE1|A0A161SXE1_HUMAN" 17 1032.641 1.18 77848 7374 2 1032.642567 517.3278 Eukaryotic translation initiation factor 3 subunit E OS=Homo sapiens OX=9606 GN=EIF3E PE=1 SV=1 11 1725.7 - 689217 - - - 1.47 - 1.785 0.044 - 445.9 1 2 0 0.0015 9 0 0 0 4.12E+07 3.50E+07 - - - 1.0418 0.9989 221125_WJC_METTL3_EV_vs_WT_F06.07377.07377.2 0.0121 18-Nov R.ADILEDK[136.11]DGK[136.11].S "sp|P52272|HNRPM_HUMAN,tr|M0R019|M0R019_HUMAN,tr|M0R0N3|M0R0N3_HUMAN,tr|A0A087X0X3|A0A087X0X3_HUMAN,tr|M0QZM1|M0QZM1_HUMAN,tr|M0QYQ7|M0QYQ7_HUMAN,tr|M0R2T0|M0R2T0_HUMAN" 7 1118.579 2.08 77851 7377 2 1118.579244 560.2968 Heterogeneous nuclear ribonucleoprotein M OS=Homo sapiens OX=9606 GN=HNRNPM PE=1 SV=3 4.23 1726.1 - 490444 - - - 0.2011 - 2.411 0.505 - 348.8 1 2 1 0.0002 10 0 0 0 1.22E+09 5.84E+08 - - - 5.2273 1 221125_WJC_METTL3_EV_vs_WT_F06.07378.07378.2 1.64E-09 22-Dec K.MTGSNTEEIDSR.L "sp|Q8N573|OXR1_HUMAN,tr|H0YC07|H0YC07_HUMAN" 2 1338.5722 0.81 77852 7378 2 1338.571937 670.2934 Oxidation resistance protein 1 OS=Homo sapiens OX=9606 GN=OXR1 PE=1 SV=2 4.14 1726.2 - 237228 - - - -0.1658 - 2.744 0.713 - 584 1 2 0 -0.0002 12 0 0 0 3.03E+06 3.72E+06 - - - 6.9631 0.9733 221125_WJC_METTL3_EV_vs_WT_F06.07379.07379.2 2.11 20-Jun R.RIVEQDTMPPK.G "sp|O00571|DDX3X_HUMAN,sp|O15523|DDX3Y_HUMAN,tr|A0A2R8YFR4|A0A2R8YFR4_HUMAN,tr|A0A2R8YCW1|A0A2R8YCW1_HUMAN,tr|A0A2R8YDH3|A0A2R8YDH3_HUMAN,tr|A0A2R8YDT5|A0A2R8YDT5_HUMAN,tr|A0A2R8Y645|A0A2R8Y645_HUMAN,tr|A0A2R8YF78|A0A2R8YF78_HUMAN,tr|A0A0D9SFB3|A0A0D9SFB3_HUMAN,tr|A0A2R8YFS5|A0A2R8YFS5_HUMAN,tr|A0A0D9SF53|A0A0D9SF53_HUMAN,tr|A0A2R8Y5G6|A0A2R8Y5G6_HUMAN,tr|A0A2R8Y7T2|A0A2R8Y7T2_HUMAN,tr|A0A0D9SG12|A0A0D9SG12_HUMAN,tr|F6S8Q4|F6S8Q4_HUMAN,tr|A0A2U3TZJ9|A0A2U3TZJ9_HUMAN,tr|A0A2R8Y4A4|A0A2R8Y4A4_HUMAN" 17 1312.6809 0.57 77853 7379 2 1312.685245 657.3477 ATP-dependent RNA helicase DDX3X OS=Homo sapiens OX=9606 GN=DDX3X PE=1 SV=3 6.07 1726.4 - 119190 - - - 3.294 - 1.474 0.141 - 111.9 1 2 0 0.0043 11 0 0 0 1.81E+06 3.16E+06 - - - 1.1306 1 221125_WJC_METTL3_EV_vs_WT_F06.07382.07382.2 2.05E-06 14/20 R.KVVGC[160.03]SC[160.03]VVVK.D sp|P25398|RS12_HUMAN 1 1233.6573 1.83 77854 7382 2 1233.658242 617.836 40S ribosomal protein S12 OS=Homo sapiens OX=9606 GN=RPS12 PE=1 SV=3 8.9 1726.8 - 1.19E+07 - - - 0.7231 - 2.706 0.604 - 553.5 1 2 0 0.0009 11 0 0 0 8.71E+08 4.76E+08 - - - 6.1948 0.995 221125_WJC_METTL3_EV_vs_WT_F06.07385.07385.2 0.0215 18-Nov R.ADILEDKDGK.S "sp|P52272|HNRPM_HUMAN,tr|M0R019|M0R019_HUMAN,tr|M0R0N3|M0R0N3_HUMAN,tr|A0A087X0X3|A0A087X0X3_HUMAN,tr|M0QZM1|M0QZM1_HUMAN,tr|M0QYQ7|M0QYQ7_HUMAN,tr|M0R2T0|M0R2T0_HUMAN" 7 1102.5506 2.07 77857 7385 2 1102.550001 552.2826 Heterogeneous nuclear ribonucleoprotein M OS=Homo sapiens OX=9606 GN=HNRNPM PE=1 SV=3 4.23 1726.9 - 2.51E+06 - - - -0.5605 - 1.956 0.306 - 366.5 1 2 1 -0.0006 10 0 0 0 1.21E+09 5.85E+08 - - - 3.1736 0.9999 221125_WJC_METTL3_EV_vs_WT_F06.07387.07387.2 1.25E-06 22-Nov K.LYTSAPNTSQGK.D "sp|Q5QJE6|TDIF2_HUMAN,tr|J3KP30|J3KP30_HUMAN" 2 1265.6252 1.1 77859 7387 2 1265.625614 633.8199 Deoxynucleotidyltransferase terminal-interacting protein 2 OS=Homo sapiens OX=9606 GN=DNTTIP2 PE=1 SV=2 8.59 1727.1 - 1.71E+06 - - - 0.3421 - 2.155 0.602 - 295.2 1 2 0 0.0004 12 0 0 0 1.73E+07 1.57E+07 - - - 5.5074 0.9998 221125_WJC_METTL3_EV_vs_WT_F06.07388.07388.2 0.00324 18-Aug K.DANGNSFATR[166.11].L "sp|P62701|RS4X_HUMAN,sp|P22090|RS4Y1_HUMAN,sp|Q8TD47|RS4Y2_HUMAN,tr|C9JEH7|C9JEH7_HUMAN" 4 1061.4766 -1 77860 7388 2 1061.475949 531.7456 "40S ribosomal protein S4, X isoform OS=Homo sapiens OX=9606 GN=RPS4X PE=1 SV=2" 5.84 1727.1 - 1.53E+06 - - - -0.5718 - 1.777 0.466 - 231 1 2 0 -0.0006 10 0 0 0 0.00E+00 0.00E+00 - - - 4.0875 0.9998 221125_WJC_METTL3_EV_vs_WT_F06.07390.07390.2 2.65E-06 20-Oct K.DSYVGDEAQSK.R "sp|P63261|ACTG_HUMAN,sp|P68133|ACTS_HUMAN,sp|P62736|ACTA_HUMAN,sp|P68032|ACTC_HUMAN,sp|P60709|ACTB_HUMAN,sp|P63267|ACTH_HUMAN,tr|A0A804GS07|A0A804GS07_HUMAN,tr|I3L3I0|I3L3I0_HUMAN,tr|G5E9R0|G5E9R0_HUMAN,tr|E7EVS6|E7EVS6_HUMAN,tr|A0A6Q8PFE4|A0A6Q8PFE4_HUMAN,tr|B8ZZJ2|B8ZZJ2_HUMAN,tr|J3KT65|J3KT65_HUMAN,tr|I3L3R2|I3L3R2_HUMAN,tr|K7EM38|K7EM38_HUMAN,tr|F6QUT6|F6QUT6_HUMAN,tr|C9JTX5|C9JTX5_HUMAN,tr|A0A6Q8PH58|A0A6Q8PH58_HUMAN,tr|F6UVQ4|F6UVQ4_HUMAN,tr|F8WB63|F8WB63_HUMAN,tr|I3L1U9|I3L1U9_HUMAN,tr|A0A804HKV3|A0A804HKV3_HUMAN,tr|A0A2R8Y793|A0A2R8Y793_HUMAN,tr|I3L4N8|I3L4N8_HUMAN,tr|C9JUM1|C9JUM1_HUMAN,tr|C9JZR7|C9JZR7_HUMAN,tr|C9JFL5|C9JFL5_HUMAN,tr|A0A2R8YGF8|A0A2R8YGF8_HUMAN,tr|A6NL76|A6NL76_HUMAN" 29 1197.515 0.99 77862 7390 2 1197.516424 599.7648 "Actin, cytoplasmic 2 OS=Homo sapiens OX=9606 GN=ACTG1 PE=1 SV=1" 4.03 1727.4 - 578151 - - - 1.2217 - 1.709 0.596 - 196 1 2 0 0.0015 11 0 0 0 2.00E+08 2.02E+08 - - - 4.8924 0.993 221125_WJC_METTL3_EV_vs_WT_F06.07393.07393.2 0.0139 16-Oct R.LK[136.11]EELEEAR[166.11].D "sp|Q04637|IF4G1_HUMAN,tr|E7EUU4|E7EUU4_HUMAN,tr|E9PGM1|E9PGM1_HUMAN,tr|C9J6B6|C9J6B6_HUMAN,tr|E7EX73|E7EX73_HUMAN,tr|A0A7I2Y1C3|A0A7I2Y1C3_HUMAN,tr|C9JF13|C9JF13_HUMAN" 7 1133.6047 2.62 77865 7393 2 1133.606651 567.8096 Eukaryotic translation initiation factor 4 gamma 1 OS=Homo sapiens OX=9606 GN=EIF4G1 PE=1 SV=4 4.49 1727.8 - 397437 - - - 1.7008 - 1.879 0.354 - 290.9 1 2 1 0.0019 9 0 0 0 1.84E+07 7.03E+06 - - - 3.4798 0.9993 221125_WJC_METTL3_EV_vs_WT_F06.07398.07398.3 0.0235 Sep-36 K.QAHTMDPQLR.L "sp|P49327|FAS_HUMAN,tr|A0A0U1RQF0|A0A0U1RQF0_HUMAN,tr|A0A0U1RRG3|A0A0U1RRG3_HUMAN" 3 1195.5768 0.94 77868 7398 3 1195.578366 399.5329 Fatty acid synthase OS=Homo sapiens OX=9606 GN=FASN PE=1 SV=3 6.74 1728.3 - 1.80E+06 - - - 1.3174 - 1.657 0.339 - 141 1 2 0 0.0016 10 0 0 0 5.94E+07 6.33E+07 - - - 3.7939 0.9959 221125_WJC_METTL3_EV_vs_WT_F06.07405.07405.2 0.095 24-Apr K.LQSSQEPEAPPPR[166.11].D "sp|Q9UNF1|MAGD2_HUMAN,tr|Q5H907|Q5H907_HUMAN,tr|Q5H909|Q5H909_HUMAN" 3 1444.7186 1.08 77875 7405 2 1444.718447 723.3666 Melanoma-associated antigen D2 OS=Homo sapiens OX=9606 GN=MAGED2 PE=1 SV=2 4.53 1729.1 - 168597 - - - -0.09 - 1.182 0.258 - 56.1 2 2 0 -0.0001 13 0 0 0 9.17E+05 8.46E+05 - - - 1.2412 0.9888 221125_WJC_METTL3_EV_vs_WT_F06.07408.07408.2 0.776 12-Jun K.EIELTHR.M sp|O43395|PRPF3_HUMAN 1 896.4716 13.06 77877 7408 2 896.470413 449.2431 U4\U6 small nuclear ribonucleoprotein Prp3 OS=Homo sapiens OX=9606 GN=PRPF3 PE=1 SV=2 5.4 1729.5 - 676000 - - - -1.3018 - 1.249 0.138 - 143.9 1 2 0 -0.0012 7 0 0 0 1.20E+07 9.16E+05 - - - 0.7644 0.9998 221125_WJC_METTL3_EV_vs_WT_F06.07411.07411.2 8.86E-05 20-Nov K.DSYVGDEAQSK[136.11].R "sp|P63261|ACTG_HUMAN,sp|P68133|ACTS_HUMAN,sp|P62736|ACTA_HUMAN,sp|P68032|ACTC_HUMAN,sp|P60709|ACTB_HUMAN,sp|P63267|ACTH_HUMAN,tr|A0A804GS07|A0A804GS07_HUMAN,tr|I3L3I0|I3L3I0_HUMAN,tr|G5E9R0|G5E9R0_HUMAN,tr|E7EVS6|E7EVS6_HUMAN,tr|A0A6Q8PFE4|A0A6Q8PFE4_HUMAN,tr|B8ZZJ2|B8ZZJ2_HUMAN,tr|J3KT65|J3KT65_HUMAN,tr|I3L3R2|I3L3R2_HUMAN,tr|K7EM38|K7EM38_HUMAN,tr|F6QUT6|F6QUT6_HUMAN,tr|C9JTX5|C9JTX5_HUMAN,tr|A0A6Q8PH58|A0A6Q8PH58_HUMAN,tr|F6UVQ4|F6UVQ4_HUMAN,tr|F8WB63|F8WB63_HUMAN,tr|I3L1U9|I3L1U9_HUMAN,tr|A0A804HKV3|A0A804HKV3_HUMAN,tr|A0A2R8Y793|A0A2R8Y793_HUMAN,tr|I3L4N8|I3L4N8_HUMAN,tr|C9JUM1|C9JUM1_HUMAN,tr|C9JZR7|C9JZR7_HUMAN,tr|C9JFL5|C9JFL5_HUMAN,tr|A0A2R8YGF8|A0A2R8YGF8_HUMAN,tr|A6NL76|A6NL76_HUMAN" 29 1205.5292 0.99 77880 7411 2 1205.530211 603.7719 "Actin, cytoplasmic 2 OS=Homo sapiens OX=9606 GN=ACTG1 PE=1 SV=1" 4.03 1729.7 - 3.69E+06 - - - 0.871 - 1.797 0.523 - 245.3 1 2 0 0.001 11 0 0 0 2.00E+08 2.02E+08 - - - 4.4891 0.9987 221125_WJC_METTL3_EV_vs_WT_F06.07413.07413.2 0.0999 16-Sep K.RTTVVAQLK.Q "sp|P60228|EIF3E_HUMAN,tr|A0A7I2V3I2|A0A7I2V3I2_HUMAN,tr|A0A7I2V570|A0A7I2V570_HUMAN,tr|A0A7I2V2Q9|A0A7I2V2Q9_HUMAN,tr|H0YBP5|H0YBP5_HUMAN,tr|A0A7I2V5Z6|A0A7I2V5Z6_HUMAN,tr|A0A7I2V2H9|A0A7I2V2H9_HUMAN,tr|B3KW56|B3KW56_HUMAN,tr|A0A7I2V4B4|A0A7I2V4B4_HUMAN,tr|A0A7I2V3I0|A0A7I2V3I0_HUMAN,tr|A0A7I2V3S3|A0A7I2V3S3_HUMAN,tr|A0A7I2V4G3|A0A7I2V4G3_HUMAN,tr|A0A7I2V3W9|A0A7I2V3W9_HUMAN,tr|H0YBR5|H0YBR5_HUMAN,tr|A0A7I2V429|A0A7I2V429_HUMAN,tr|A0A7I2V2W0|A0A7I2V2W0_HUMAN,tr|A0A161SXE1|A0A161SXE1_HUMAN" 17 1014.6186 1.18 77882 7413 2 1014.618422 508.3166 Eukaryotic translation initiation factor 3 subunit E OS=Homo sapiens OX=9606 GN=EIF3E PE=1 SV=1 11 1729.8 - 2.70E+06 - - - -0.1547 - 1.777 0.19 - 362 1 2 0 -0.0002 9 0 0 0 4.12E+07 3.50E+07 - - - 2.1076 0.9769 221125_WJC_METTL3_EV_vs_WT_F06.07419.07419.2 0.000352 16-Sep S.C[160.03]VGVFQHGK[136.11].V "sp|P54652|HSP72_HUMAN,sp|P0DMV8|HS71A_HUMAN,sp|P34931|HS71L_HUMAN,sp|P11142|HSP7C_HUMAN,sp|P0DMV9|HS71B_HUMAN,tr|E9PQQ4|E9PQQ4_HUMAN,tr|E9PNE6|E9PNE6_HUMAN,tr|E9PKE3|E9PKE3_HUMAN,tr|E9PLF4|E9PLF4_HUMAN,tr|Q53FA3|Q53FA3_HUMAN,tr|E9PI65|E9PI65_HUMAN,tr|V9GZ37|V9GZ37_HUMAN,tr|E9PK54|E9PK54_HUMAN,tr|E9PN25|E9PN25_HUMAN,tr|E9PPY6|E9PPY6_HUMAN,tr|E9PQK7|E9PQK7_HUMAN,tr|A0A0G2JIW1|A0A0G2JIW1_HUMAN" 17 1038.516 5.27 77888 7419 2 1038.517318 520.2653 Heat shock-related 70 kDa protein 2 OS=Homo sapiens OX=9606 GN=HSPA2 PE=1 SV=1 8.23 1730.5 - 806233 - - - 1.2354 - 1.781 0.408 - 249.1 1 1 0 0.0013 9 0 0 0 9.41E+07 1.79E+07 - - - 3.7239 0.9999 221125_WJC_METTL3_EV_vs_WT_F06.07420.07420.2 1.90E-06 20-Nov K.ENAGEDPGLAR.Q sp|P81605|DCD_HUMAN 1 1127.5207 999 77889 7420 2 1127.520753 564.7676 Dermcidin OS=Homo sapiens OX=9606 GN=DCD PE=1 SV=2 4.14 1730.6 - 747694 - - - 0.0328 - 2.117 0.519 - 304.8 1 2 0 0 11 0 0 0 2.38E+08 0.00E+00 - - - 4.9032 0.9998 221125_WJC_METTL3_EV_vs_WT_F06.07425.07425.2 0.00034 16-Sep R.IDDIVSGHK[136.11].K "sp|P49368|TCPG_HUMAN,tr|B4DUR8|B4DUR8_HUMAN" 2 990.5226 0.22 77892 7425 2 990.522469 496.2686 T-complex protein 1 subunit gamma OS=Homo sapiens OX=9606 GN=CCT3 PE=1 SV=4 5.21 1731.2 - 5.66E+06 - - - -0.0919 - 2.089 0.439 - 228.8 1 2 0 -0.0001 9 0 0 0 8.48E+07 3.79E+08 - - - 4.4147 0.9831 221125_WJC_METTL3_EV_vs_WT_F06.07427.07427.2 0.000533 14-Aug L.DDIVSGHK[136.11].K "sp|P49368|TCPG_HUMAN,tr|B4DUR8|B4DUR8_HUMAN" 2 877.4385 0.33 77894 7427 2 877.438194 439.7265 T-complex protein 1 subunit gamma OS=Homo sapiens OX=9606 GN=CCT3 PE=1 SV=4 5.21 1731.3 - 2.95E+06 - - - -0.3442 - 1.72 0.401 - 211.5 1 1 0 -0.0003 8 0 0 0 5.22E+07 1.58E+08 - - - 3.6383 0.9982 221125_WJC_METTL3_EV_vs_WT_F06.07429.07429.3 0.0164 Oct-40 R.K[136.11]VVGC[160.03]SC[160.03]VVVK.D sp|P25398|RS12_HUMAN 1 1241.6716 - 77896 7429 3 1241.670351 414.8978 40S ribosomal protein S12 OS=Homo sapiens OX=9606 GN=RPS12 PE=1 SV=3 8.9 1731.4 - 1.98E+06 - - - -0.9656 - 1.701 0.256 - 172.9 1 2 0 -0.0012 11 0 0 0 - - - - - 2.9029 0.9862 221125_WJC_METTL3_EV_vs_WT_F06.07430.07430.2 0.002 14-Aug K.AKFENLC[160.03]K.F "sp|Q58FF8|H90B2_HUMAN,sp|P08238|HS90B_HUMAN" 2 1008.5063 0.73 77897 7430 2 1008.504837 505.2604 Putative heat shock protein HSP 90-beta 2 OS=Homo sapiens OX=9606 GN=HSP90AB2P PE=1 SV=2 8.24 1731.5 - 1.88E+06 - - - -1.4031 - 1.433 0.323 - 160.3 1 2 1 -0.0014 8 0 0 0 2.48E+07 3.41E+07 - - - 2.5113 0.8065 221125_WJC_METTL3_EV_vs_WT_F06.07435.07435.3 0.557 Jul-40 R.LHGLDEEAEQK.L "sp|P33991|MCM4_HUMAN,tr|A0A3B3IT92|A0A3B3IT92_HUMAN,tr|A0A3B3IU45|A0A3B3IU45_HUMAN,tr|A0A3B3ITP6|A0A3B3ITP6_HUMAN,tr|E5RG31|E5RG31_HUMAN,tr|A0A3B3IS57|A0A3B3IS57_HUMAN" 6 1267.6044 0.61 77902 7435 3 1267.603241 423.5421 DNA replication licensing factor MCM4 OS=Homo sapiens OX=9606 GN=MCM4 PE=1 SV=5 4.4 1732 - 856268 - - - -0.9498 - 1.398 0.061 - 71.5 2 2 0 -0.0012 11 0 0 0 2.00E+07 3.27E+07 - - - 0.0322 0.9103 221125_WJC_METTL3_EV_vs_WT_F06.07441.07441.2 0.00583 14-Aug K.AK[136.11]FENLC[160.03]K[136.11].F "sp|Q58FF8|H90B2_HUMAN,sp|P08238|HS90B_HUMAN" 2 1024.5347 0.77 77906 7441 2 1024.535497 513.2746 Putative heat shock protein HSP 90-beta 2 OS=Homo sapiens OX=9606 GN=HSP90AB2P PE=1 SV=2 8.24 1732.7 - 1.41E+06 - - - 0.8248 - 1.555 0.065 - 170.9 1 2 1 0.0008 8 0 0 0 2.52E+07 3.26E+07 - - - 0.8523 0.9416 221125_WJC_METTL3_EV_vs_WT_F06.07446.07446.2 0.112 16-Jul R.EHGAFDAVK.C "sp|P11586|C1TC_HUMAN,tr|F5H2F4|F5H2F4_HUMAN,tr|V9GZ78|V9GZ78_HUMAN,tr|V9GYY3|V9GYY3_HUMAN,tr|A0A494C1T2|A0A494C1T2_HUMAN" 5 972.4665 1.76 77909 7446 2 972.466521 487.2405 "C-1-tetrahydrofolate synthase, cytoplasmic OS=Homo sapiens OX=9606 GN=MTHFD1 PE=1 SV=4" 5.32 1733.3 - 875761 - - - 0.0267 - 1.202 0.003 - 113.2 2 2 0 0 9 0 0 0 3.32E+07 1.89E+07 - - - -0.539 0.9996 221125_WJC_METTL3_EV_vs_WT_F06.07452.07452.2 6.96E-06 14/20 K.SPEQQLSATQK[136.11].F "sp|P52294|IMA5_HUMAN,tr|C9JWD9|C9JWD9_HUMAN,tr|C9JYI4|C9JYI4_HUMAN,tr|C9J352|C9J352_HUMAN,tr|C9J4U1|C9J4U1_HUMAN,tr|F2Z3G4|F2Z3G4_HUMAN" 6 1223.6237 0.86 77913 7452 2 1223.627157 612.8191 Importin subunit alpha-5 OS=Homo sapiens OX=9606 GN=KPNA1 PE=1 SV=3 5.72 1734.1 - 760706 - - - 2.7999 - 2.437 0.518 - 454.8 1 2 0 0.0034 11 0 0 0 1.75E+08 2.03E+08 - - - 5.2756 0.997 221125_WJC_METTL3_EV_vs_WT_F06.07453.07453.2 0.000228 22-Dec K.IQSSLSSASPSK.A sp|Q5W0B1|OBI1_HUMAN 1 1190.6143 1.19 77914 7453 2 1190.620032 596.3144 ORC ubiquitin ligase 1 OS=Homo sapiens OX=9606 GN=OBI1 PE=1 SV=1 8.75 1734.2 - 539691 - - - 4.8294 - 2.097 0.448 - 389 1 2 0 0.0058 12 0 0 0 1.28E+07 1.08E+07 - - - 4.2965 0.9999 221125_WJC_METTL3_EV_vs_WT_F06.07455.07455.2 8.64E-06 20-Sep K.C[160.03]NTC[160.03]GEPITDR[166.11].M "sp|Q15942|ZYX_HUMAN,tr|H0Y2Y8|H0Y2Y8_HUMAN,tr|C9JJK5|C9JJK5_HUMAN" 3 1331.5474 4.72 77916 7455 2 1331.54794 666.781 Zyxin OS=Homo sapiens OX=9606 GN=ZYX PE=1 SV=1 4.37 1734.5 - 404023 - - - 0.4393 - 2.033 0.551 - 336.4 1 2 0 0.0006 11 0 0 0 9.68E+07 2.05E+07 - - - 5.0299 0.9962 221125_WJC_METTL3_EV_vs_WT_F06.07458.07458.2 0.0218 16-Aug R.KFDGVEGPR.T "sp|Q6PKG0|LARP1_HUMAN,tr|A0A0B4J210|A0A0B4J210_HUMAN,tr|H0YBW1|H0YBW1_HUMAN,tr|E5RH50|E5RH50_HUMAN,tr|H0YAN4|H0YAN4_HUMAN" 5 1003.5087 1.22 77917 7458 2 1003.510765 502.7616 La-related protein 1 OS=Homo sapiens OX=9606 GN=LARP1 PE=1 SV=2 6.07 1734.9 - 762355 - - - 2.0638 - 1.574 0.221 - 211.7 1 2 0 0.0021 9 0 0 0 7.28E+07 5.97E+07 - - - 1.985 0.9975 221125_WJC_METTL3_EV_vs_WT_F06.07460.07460.2 0.0882 14-Jul R.SLSEEIKR.L sp|P15924|DESP_HUMAN 1 960.524 31.01 77918 7460 2 960.524029 481.2693 Desmoplakin OS=Homo sapiens OX=9606 GN=DSP PE=1 SV=3 5.86 1735.1 - 6.03E+06 - - - 0.0198 - 1.465 0.192 - 142.4 1 2 0 0 8 0 0 0 1.73E+08 5.56E+06 - - - 1.6108 0.9992 221125_WJC_METTL3_EV_vs_WT_F06.07461.07461.2 0.00402 16-Aug R.K[136.11]FDGVEGPR[166.11].T "sp|Q6PKG0|LARP1_HUMAN,tr|A0A0B4J210|A0A0B4J210_HUMAN,tr|H0YBW1|H0YBW1_HUMAN,tr|E5RH50|E5RH50_HUMAN,tr|H0YAN4|H0YAN4_HUMAN" 5 1021.5312 1.21 77919 7461 2 1021.530586 511.7729 La-related protein 1 OS=Homo sapiens OX=9606 GN=LARP1 PE=1 SV=2 6.07 1735.2 - 809691 - - - -0.5658 - 1.747 0.26 - 208.6 1 2 0 -0.0006 9 0 0 0 7.28E+07 6.01E+07 - - - 2.5752 0.9997 221125_WJC_METTL3_EV_vs_WT_F06.07463.07463.2 2.82E-05 13/24 R.EVQETTVTEGAAK[136.11].L "sp|Q9NXH9|TRM1_HUMAN,tr|K7EQQ8|K7EQQ8_HUMAN,tr|K7EQU7|K7EQU7_HUMAN,tr|K7EQY6|K7EQY6_HUMAN,tr|K7ERR5|K7ERR5_HUMAN,tr|K7ENI9|K7ENI9_HUMAN" 6 1369.6816 0.7 77921 7463 2 1369.677793 685.8481 tRNA (guanine(26)-N(2))-dimethyltransferase OS=Homo sapiens OX=9606 GN=TRMT1 PE=1 SV=1 4.25 1735.4 - 452837 - - - -2.808 - 2.417 0.57 - 701.9 1 2 0 -0.0038 13 0 0 0 1.02E+07 1.45E+07 - - - 5.5148 1 221125_WJC_METTL3_EV_vs_WT_F06.07467.07467.2 3.57E-09 13/24 R.YSTSGSSGLTTGK.L "sp|Q16891|MIC60_HUMAN,tr|B9A067|B9A067_HUMAN,tr|A0A087WYS0|A0A087WYS0_HUMAN,tr|D6RAW4|D6RAW4_HUMAN" 4 1244.5885 1.1 77923 7467 2 1244.587263 623.3015 MICOS complex subunit MIC60 OS=Homo sapiens OX=9606 GN=IMMT PE=1 SV=1 8.59 1735.9 - 2.74E+06 - - - -0.9626 - 2.535 0.675 - 455.1 1 2 0 -0.0012 13 0 0 0 9.71E+07 8.81E+07 - - - 6.4135 1 221125_WJC_METTL3_EV_vs_WT_F06.07468.07468.2 2.29E-09 13/24 R.YSTSGSSGLTTGK[136.11].L "sp|Q16891|MIC60_HUMAN,tr|B9A067|B9A067_HUMAN,tr|A0A087WYS0|A0A087WYS0_HUMAN,tr|D6RAW4|D6RAW4_HUMAN" 4 1252.6027 1.1 77924 7468 2 1252.598053 627.3086 MICOS complex subunit MIC60 OS=Homo sapiens OX=9606 GN=IMMT PE=1 SV=1 8.59 1736 - 3.87E+06 - - - -3.6787 - 2.591 0.649 - 468.4 1 2 0 -0.0046 13 0 0 0 9.71E+07 8.81E+07 - - - 6.2765 0.9998 221125_WJC_METTL3_EV_vs_WT_F06.07469.07469.2 0.000263 24-Nov R.EVQETTVTEGAAK.L "sp|Q9NXH9|TRM1_HUMAN,tr|K7EQQ8|K7EQQ8_HUMAN,tr|K7EQU7|K7EQU7_HUMAN,tr|K7EQY6|K7EQY6_HUMAN,tr|K7ERR5|K7ERR5_HUMAN,tr|K7ENI9|K7ENI9_HUMAN" 6 1361.6674 0.7 77925 7469 2 1361.667173 681.841 tRNA (guanine(26)-N(2))-dimethyltransferase OS=Homo sapiens OX=9606 GN=TRMT1 PE=1 SV=1 4.25 1736.1 - 349341 - - - -0.1953 - 1.9 0.472 - 371.8 1 2 0 -0.0003 13 0 0 0 1.02E+07 1.45E+07 - - - 4.1744 0.9992 221125_WJC_METTL3_EV_vs_WT_F06.07480.07480.2 0.000508 18-Nov R.KIGDTSVSYK.Y sp|P20700|LMNB1_HUMAN 1 1096.5764 1.39 77931 7480 2 1096.579467 549.2955 Lamin-B1 OS=Homo sapiens OX=9606 GN=LMNB1 PE=1 SV=2 8.5 1737.4 - 822715 - - - 2.7604 - 2.147 0.389 - 316.4 1 2 0 0.003 10 0 0 0 7.31E+07 5.24E+07 - - - 4.046 0.9999 221125_WJC_METTL3_EV_vs_WT_F06.07483.07483.2 8.09E-05 28-Nov R.MEAGEAAPPAGAGGR.A "sp|Q8N5Z5|KCD17_HUMAN,tr|A0A087WX35|A0A087WX35_HUMAN" 2 1340.6143 5.09 77933 7483 2 1340.614789 671.3144 BTB\POZ domain-containing protein KCTD17 OS=Homo sapiens OX=9606 GN=KCTD17 PE=1 SV=3 4.53 1737.8 - 691051 - - - 0.3663 - 2.564 0.534 - 220.5 1 2 0 0.0005 15 0 0 0 1.60E+08 3.15E+07 - - - 5.2999 1 221125_WJC_METTL3_EV_vs_WT_F06.07487.07487.2 6.60E-06 14/22 K.VGGTSDVEVNEK.K "sp|P10809|CH60_HUMAN,tr|A0A7I2V2X6|A0A7I2V2X6_HUMAN,tr|A0A7I2YQK6|A0A7I2YQK6_HUMAN,tr|A0A7I2V599|A0A7I2V599_HUMAN" 4 1232.5885 1.31 77935 7487 2 1232.589685 617.3015 "60 kDa heat shock protein, mitochondrial OS=Homo sapiens OX=9606 GN=HSPD1 PE=1 SV=2" 4.14 1738.3 - 3.91E+06 - - - 0.993 - 2.718 0.622 - 711.8 1 2 0 0.0012 12 0 0 0 1.51E+08 1.16E+08 - - - 6.2656 0.9977 221125_WJC_METTL3_EV_vs_WT_F06.07488.07488.2 0.0108 14-Oct R.RPTWAEER.R "sp|Q8ND56|LS14A_HUMAN,tr|A0A096LP11|A0A096LP11_HUMAN,tr|A0A140TA76|A0A140TA76_HUMAN,tr|A0A0G2JQ95|A0A0G2JQ95_HUMAN" 4 1043.5148 0.99 77936 7488 2 1043.515721 522.7647 Protein LSM14 homolog A OS=Homo sapiens OX=9606 GN=LSM14A PE=1 SV=3 6.14 1738.4 - 4.10E+06 - - - 0.8423 - 2.187 0.061 - 320 1 2 0 0.0009 8 0 0 0 7.93E+09 8.02E+09 - - - 1.8513 0.9999 221125_WJC_METTL3_EV_vs_WT_F06.07490.07490.2 0.000544 20-Sep R.EYNEDEDPAAR.R "sp|Q13123|RED_HUMAN,tr|D6RAY9|D6RAY9_HUMAN,tr|D6REL4|D6REL4_HUMAN,tr|E7EQZ7|E7EQZ7_HUMAN,tr|D6RCQ4|D6RCQ4_HUMAN" 5 1307.5266 1.54 77938 7490 2 1307.525299 654.7706 Protein Red OS=Homo sapiens OX=9606 GN=IK PE=1 SV=3 3.83 1738.6 - 450990 - - - -0.9866 - 1.836 0.569 - 218.7 1 2 0 -0.0013 11 0 0 0 6.07E+07 3.93E+07 - - - 4.8869 0.9998 221125_WJC_METTL3_EV_vs_WT_F06.07493.07493.2 0.00144 20-Sep K.ADGGTQVIDTK[136.11].N "sp|P09622|DLDH_HUMAN,tr|E9PEX6|E9PEX6_HUMAN" 2 1111.5601 4.16 77939 7493 2 1111.559736 556.7873 "Dihydrolipoyl dehydrogenase, mitochondrial OS=Homo sapiens OX=9606 GN=DLD PE=1 SV=2" 4.21 1739 - 3.43E+06 - - - -0.2987 - 2.014 0.388 - 325.8 1 2 0 -0.0003 11 0 0 0 7.73E+08 1.86E+08 - - - 3.8007 0.9977 221125_WJC_METTL3_EV_vs_WT_F06.07495.07495.2 2.83E-05 13/22 K.LK[136.11]GELESSDQVR[166.11].E "sp|Q9P2E9|RRBP1_HUMAN,tr|A0A087WU26|A0A087WU26_HUMAN,tr|A0A087WVV2|A0A087WVV2_HUMAN,tr|F8W7S5|F8W7S5_HUMAN" 4 1377.7219 1.08 77941 7495 2 1377.724392 689.8682 Ribosome-binding protein 1 OS=Homo sapiens OX=9606 GN=RRBP1 PE=1 SV=5 4.68 1739.2 - 726254 - - - 1.8248 - 2.237 0.558 - 363.6 1 2 1 0.0025 12 0 0 0 1.57E+07 1.45E+07 - - - 5.28 1 221125_WJC_METTL3_EV_vs_WT_F06.07499.07499.3 0.000474 13/36 K.TVKPPEDQLK.S "sp|P42694|HELZ_HUMAN,tr|J3QS41|J3QS41_HUMAN" 2 1153.6343 2.3 77943 7499 3 1153.635212 385.552 Probable helicase with zinc finger domain OS=Homo sapiens OX=9606 GN=HELZ PE=1 SV=2 5.73 1739.7 - 5.00E+06 - - - 0.8001 - 2.132 0.464 - 239.3 1 2 0 0.0009 10 0 0 0 1.69E+08 7.34E+07 - - - 5.9238 0.9916 221125_WJC_METTL3_EV_vs_WT_F06.07501.07501.3 2.43E-05 Dec-48 K.IIVGDATEKDASK.K sp|Q96I25|SPF45_HUMAN 1 1345.7089 4.15 77945 7501 3 1345.712717 449.5769 Splicing factor 45 OS=Homo sapiens OX=9606 GN=RBM17 PE=1 SV=1 4.56 1739.9 - 623648 - - - 2.829 - 2.207 0.276 - 121.9 1 2 1 0.0038 13 0 0 0 1.83E+07 4.40E+06 - - - 3.7624 1 221125_WJC_METTL3_EV_vs_WT_F06.07502.07502.2 0.000104 15/22 K.VAEVEGEQVDNK.A sp|O95202|LETM1_HUMAN 1 1315.6256 1.03 77946 7502 2 1315.628744 658.8201 Mitochondrial proton\calcium exchanger protein OS=Homo sapiens OX=9606 GN=LETM1 PE=1 SV=1 4 1740 - 537851 - - - 2.4087 - 2.607 0.566 - 823.9 1 2 0 0.0032 12 0 0 0 7.45E+07 7.24E+07 - - - 5.7417 0.9996 221125_WJC_METTL3_EV_vs_WT_F06.07503.07503.2 5.38E-09 13/24 K.STVNC[160.03]STTPVAER[166.11].F "sp|Q99567|NUP88_HUMAN,tr|J3KMX1|J3KMX1_HUMAN,tr|I3L245|I3L245_HUMAN" 3 1430.6699 2.22 77947 7503 2 1430.674424 716.3422 Nuclear pore complex protein Nup88 OS=Homo sapiens OX=9606 GN=NUP88 PE=1 SV=2 5.72 1740.1 - 430508 - - - 3.1531 - 2.552 0.574 - 759.9 1 2 0 0.0045 13 0 0 0 2.45E+07 1.10E+07 - - - 5.6837 0.9988 221125_WJC_METTL3_EV_vs_WT_F06.07507.07507.2 0.00365 14-Nov R.R[166.11]PTWAEER[166.11].R "sp|Q8ND56|LS14A_HUMAN,tr|A0A096LP11|A0A096LP11_HUMAN,tr|A0A140TA76|A0A140TA76_HUMAN,tr|A0A0G2JQ95|A0A0G2JQ95_HUMAN" 4 1063.5314 0.99 77949 7507 2 1063.531371 532.773 Protein LSM14 homolog A OS=Homo sapiens OX=9606 GN=LSM14A PE=1 SV=3 6.14 1740.6 - 3.72E+07 - - - -0.0103 - 2.029 0.142 - 397.1 1 2 0 0 8 0 0 0 7.94E+09 8.03E+09 - - - 2.2237 0.9951 221125_WJC_METTL3_EV_vs_WT_F06.07508.07508.3 0.0181 Dec-40 K.IAVEAQNKYER.E sp|P12270|TPR_HUMAN 1 1319.6834 2.06 77950 7508 3 1319.686567 440.9017 Nucleoprotein TPR OS=Homo sapiens OX=9606 GN=TPR PE=1 SV=3 6.14 1740.7 - 2.46E+06 - - - 2.4271 - 2.688 0.234 - 375.7 1 2 1 0.0032 11 0 0 0 1.72E+08 8.36E+07 - - - 3.957 0.9496 221125_WJC_METTL3_EV_vs_WT_F06.07509.07509.3 0.0304 Oct-40 K.IAVEAQNK[136.11]YER[166.11].E sp|P12270|TPR_HUMAN 1 1337.7058 2.7 77951 7509 3 1337.70943 446.9092 Nucleoprotein TPR OS=Homo sapiens OX=9606 GN=TPR PE=1 SV=3 6.14 1740.8 - 1.18E+06 - - - 2.6882 - 2.135 0.155 - 209.4 1 2 1 0.0036 11 0 0 0 1.70E+08 6.31E+07 - - - 2.4218 0.9996 221125_WJC_METTL3_EV_vs_WT_F06.07510.07510.2 0.000675 18-Nov K.TVKPPEDQLK.S "sp|P42694|HELZ_HUMAN,tr|J3QS41|J3QS41_HUMAN" 2 1153.6343 1.92 77952 7510 2 1153.635229 577.8244 Probable helicase with zinc finger domain OS=Homo sapiens OX=9606 GN=HELZ PE=1 SV=2 5.73 1740.9 - 751341 - - - 0.8148 - 1.631 0.398 - 192.8 1 2 0 0.0009 10 0 0 0 3.16E+07 1.64E+07 - - - 3.3458 0.98 221125_WJC_METTL3_EV_vs_WT_F06.07512.07512.2 0.303 18-Jul K.TVK[136.11]PPEDQLK[136.11].S "sp|P42694|HELZ_HUMAN,tr|J3QS41|J3QS41_HUMAN" 2 1169.6627 1.89 77954 7512 2 1169.660075 585.8386 Probable helicase with zinc finger domain OS=Homo sapiens OX=9606 GN=HELZ PE=1 SV=2 5.73 1741.2 - 350466 - - - -2.2348 - 1.049 0.217 - 92.8 1 2 0 -0.0026 10 0 0 0 3.08E+07 1.63E+07 - - - 0.7765 0.9998 221125_WJC_METTL3_EV_vs_WT_F06.07513.07513.2 0.0168 28-Nov R.MEAGEAAPPAGAGGR[166.11].A "sp|Q8N5Z5|KCD17_HUMAN,tr|A0A087WX35|A0A087WX35_HUMAN" 2 1350.6226 5.06 77955 7513 2 1350.623761 676.3186 BTB\POZ domain-containing protein KCTD17 OS=Homo sapiens OX=9606 GN=KCTD17 PE=1 SV=3 4.53 1741.3 - 258925 - - - 0.8833 - 2.327 0.497 - 270.2 1 2 0 0.0012 15 0 0 0 1.55E+08 3.06E+07 - - - 4.7879 0.9997 221125_WJC_METTL3_EV_vs_WT_F06.07514.07514.2 7.75E-07 26-Aug R.LGPSTGSTAETQC[160.03]R[166.11].N "sp|Q5T200|ZC3HD_HUMAN,tr|A0A7I2V4I5|A0A7I2V4I5_HUMAN" 2 1473.6757 1.14 77956 7514 2 1473.678858 737.8451 Zinc finger CCCH domain-containing protein 13 OS=Homo sapiens OX=9606 GN=ZC3H13 PE=1 SV=1 5.99 1741.4 - 204946 - - - 2.1253 - 2.03 0.565 - 193.1 1 2 0 0.0031 14 0 0 0 1.87E+07 1.64E+07 - - - 4.9899 0.9999 221125_WJC_METTL3_EV_vs_WT_F06.07519.07519.2 8.48E-05 14/22 K.VAEVEGEQVDNK[136.11].A sp|O95202|LETM1_HUMAN 1 1323.6398 1.03 77959 7519 2 1323.640754 662.8272 Mitochondrial proton\calcium exchanger protein OS=Homo sapiens OX=9606 GN=LETM1 PE=1 SV=1 4 1742.1 - 1.33E+06 - - - 0.7396 - 2.717 0.533 - 772.9 1 2 0 0.001 12 0 0 0 7.45E+07 7.25E+07 - - - 5.6074 0.9933 221125_WJC_METTL3_EV_vs_WT_F06.07522.07522.3 0.0632 Aug-36 K.TVK[136.11]PPEDQLK[136.11].S "sp|P42694|HELZ_HUMAN,tr|J3QS41|J3QS41_HUMAN" 2 1169.6627 2.33 77960 7522 3 1169.663404 390.8948 Probable helicase with zinc finger domain OS=Homo sapiens OX=9606 GN=HELZ PE=1 SV=2 5.73 1742.5 - 1.81E+06 - - - 0.6113 - 1.382 0.23 - 72.2 1 2 0 0.0007 10 0 0 0 1.77E+08 7.60E+07 - - - 2.0489 0.9998 221125_WJC_METTL3_EV_vs_WT_F06.07524.07524.2 1.76E-05 16-Nov R.HAALQDIGK.N "sp|Q9ULX3|NOB1_HUMAN,tr|H3BUR4|H3BUR4_HUMAN" 2 951.5138 0.53 77961 7524 2 951.512294 476.7642 RNA-binding protein NOB1 OS=Homo sapiens OX=9606 GN=NOB1 PE=1 SV=1 6.74 1742.7 - 6.80E+06 - - - -1.5617 - 2.118 0.539 - 495.9 1 2 0 -0.0015 9 0 0 0 1.57E+08 2.95E+08 - - - 5.1927 0.9978 221125_WJC_METTL3_EV_vs_WT_F06.07526.07526.2 0.00031 22-Dec K.LKGELESSDQVR.E "sp|Q9P2E9|RRBP1_HUMAN,tr|A0A087WU26|A0A087WU26_HUMAN,tr|A0A087WVV2|A0A087WVV2_HUMAN,tr|F8W7S5|F8W7S5_HUMAN" 4 1359.6994 1.08 77963 7526 2 1359.701349 680.857 Ribosome-binding protein 1 OS=Homo sapiens OX=9606 GN=RRBP1 PE=1 SV=5 4.68 1742.9 - 579402 - - - 1.4275 - 2.114 0.524 - 318.9 1 2 1 0.0019 12 0 0 0 1.57E+07 1.45E+07 - - - 4.8803 0.9869 221125_WJC_METTL3_EV_vs_WT_F06.07532.07532.2 0.00406 16-Sep R.SDSYSQSLK.S sp|Q9H8W4|PKHF2_HUMAN 1 1013.4666 1.17 77967 7532 2 1013.471932 507.7406 Pleckstrin homology domain-containing family F member 2 OS=Homo sapiens OX=9606 GN=PLEKHF2 PE=1 SV=1 5.55 1743.6 - 655366 - - - 5.3056 - 1.385 0.401 - 221.8 1 2 0 0.0054 9 0 0 0 2.90E+07 2.48E+07 - - - 2.9434 0.9888 221125_WJC_METTL3_EV_vs_WT_F06.07537.07537.2 0.191 14-Aug R.RPTWAEER[166.11].R "sp|Q8ND56|LS14A_HUMAN,tr|A0A096LP11|A0A096LP11_HUMAN,tr|A0A140TA76|A0A140TA76_HUMAN,tr|A0A0G2JQ95|A0A0G2JQ95_HUMAN" 4 1053.5231 - 77970 7537 2 1053.522676 527.7688 Protein LSM14 homolog A OS=Homo sapiens OX=9606 GN=LSM14A PE=1 SV=3 6.14 1744.3 - 3.10E+06 - - - -0.4138 - 1.647 0.001 - 193.2 1 2 0 -0.0004 8 0 0 0 - - - - - 0.5531 0.9765 221125_WJC_METTL3_EV_vs_WT_F06.07538.07538.2 0.182 14-Jul T.C[160.03]FHMDTC[160.03]K[136.11].Y "sp|Q86U44|MTA70_HUMAN,tr|H0YFV6|H0YFV6_HUMAN" 2 1105.4235 0.001 77971 7538 2 1105.424643 553.719 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 6.73 1744.3 - 7.18E+06 - - - 1.0729 - 1.229 0.534 - 151.9 1 1 0 0.0012 8 0 0 0 0.00E+00 2.11E+08 - - - 3.6066 0.9999 221125_WJC_METTL3_EV_vs_WT_F06.07539.07539.2 0.000868 24-Oct K.EDIYSGGGGGGSR.S sp|Q13151|ROA0_HUMAN 1 1210.5214 1.57 77972 7539 2 1210.519877 606.268 Heterogeneous nuclear ribonucleoprotein A0 OS=Homo sapiens OX=9606 GN=HNRNPA0 PE=1 SV=1 4.37 1744.5 - 1.05E+06 - - - -1.2945 - 2.07 0.586 - 317.3 1 2 0 -0.0016 13 0 0 0 6.17E+07 3.92E+07 - - - 5.236 0.9999 221125_WJC_METTL3_EV_vs_WT_F06.07540.07540.2 5.69E-05 22-Oct K.ASDVDTSSSTLR[166.11].K sp|Q96T58|MINT_HUMAN 1 1247.5869 1.55 77973 7540 2 1247.587215 624.8007 Msx2-interacting protein OS=Homo sapiens OX=9606 GN=SPEN PE=1 SV=1 4.21 1744.6 - 793689 - - - 0.2573 - 1.927 0.513 - 392 1 2 0 0.0003 12 0 0 0 2.57E+07 1.66E+07 - - - 4.5559 0.9967 221125_WJC_METTL3_EV_vs_WT_F06.07547.07547.2 0.000739 24-Jul R.GSGVNAAGDGTIR.E "sp|P22735|TGM1_HUMAN,tr|H0YN27|H0YN27_HUMAN" 2 1173.5738 6.77 77977 7547 2 1173.568864 587.7942 Protein-glutamine gamma-glutamyltransferase K OS=Homo sapiens OX=9606 GN=TGM1 PE=1 SV=4 5.84 1745.4 - 443257 - - - -4.2179 - 1.594 0.452 - 139.5 1 2 0 -0.005 13 0 0 0 3.32E+07 4.90E+06 - - - 3.5746 0.9993 221125_WJC_METTL3_EV_vs_WT_F06.07551.07551.2 1.88E-05 20-Aug R.HAAAYPGGIDR.F sp|O00358|FOXE1_HUMAN 1 1126.552 1.08 77979 7551 2 1126.550016 564.2833 Forkhead box protein E1 OS=Homo sapiens OX=9606 GN=FOXE1 PE=1 SV=3 6.74 1746 - 703276 - - - -1.7221 - 1.904 0.332 - 196.2 1 2 0 -0.0019 11 0 0 0 1.08E+07 1.01E+07 - - - 3.2346 0.7643 221125_WJC_METTL3_EV_vs_WT_F06.07556.07556.2 0.284 12-Aug Q.SLHNGLR[166.11].A sp|P78560|CRADD_HUMAN 1 805.4434 0.88 77980 7556 2 805.442581 403.729 Death domain-containing protein CRADD OS=Homo sapiens OX=9606 GN=CRADD PE=1 SV=1 9.49 1746.6 - 700378 - - - -1.023 - 1.359 0.164 - 239 1 1 0 -0.0008 7 0 0 0 2.18E+07 2.47E+07 - - - 1.224 0.9998 221125_WJC_METTL3_EV_vs_WT_F06.07562.07562.2 2.29E-08 13/20 R.SDEGQLSPATR.G "sp|Q15149|PLEC_HUMAN,tr|E9PMV1|E9PMV1_HUMAN,tr|H0YDN1|H0YDN1_HUMAN" 3 1159.5469 1.95 77984 7562 2 1159.548057 580.7807 Plectin OS=Homo sapiens OX=9606 GN=PLEC PE=1 SV=3 4.37 1747.3 - 551595 - - - 0.9719 - 2.346 0.455 - 886.3 1 2 0 0.0011 11 0 0 0 6.12E+07 3.13E+07 - - - 4.7081 1 221125_WJC_METTL3_EV_vs_WT_F06.07564.07564.2 6.86E-09 13/26 R.LGPSTGSTAETQC[160.03]R.N "sp|Q5T200|ZC3HD_HUMAN,tr|A0A7I2V4I5|A0A7I2V4I5_HUMAN" 2 1463.6675 1.14 77986 7564 2 1463.667416 732.841 Zinc finger CCCH domain-containing protein 13 OS=Homo sapiens OX=9606 GN=ZC3H13 PE=1 SV=1 5.99 1747.6 - 358273 - - - -0.0273 - 2.85 0.655 - 660.3 1 2 0 0 14 0 0 0 1.87E+07 1.64E+07 - - - 6.507 0.9988 221125_WJC_METTL3_EV_vs_WT_F06.07568.07568.2 0.508 14-Sep K.KYQLAVTK.V "sp|Q8NDV3|SMC1B_HUMAN,sp|Q14683|SMC1A_HUMAN,tr|G8JLG1|G8JLG1_HUMAN,tr|A0A6Q8PHC3|A0A6Q8PHC3_HUMAN" 4 949.5597 0.75 77988 7568 2 949.559905 475.7871 Structural maintenance of chromosomes protein 1B OS=Homo sapiens OX=9606 GN=SMC1B PE=2 SV=2 9.7 1748.1 - 1.65E+06 - - - 0.2506 - 1.767 0.198 - 325.5 1 2 0 0.0002 8 0 0 0 3.57E+07 4.77E+07 - - - 2.2203 0.9959 221125_WJC_METTL3_EV_vs_WT_F06.07575.07575.3 0.205 Jun-40 K.YELGRPAANTK.L "sp|P62241|RS8_HUMAN,tr|Q5JR95|Q5JR95_HUMAN" 2 1218.6357 0.91 77994 7575 3 1218.635245 407.2192 40S ribosomal protein S8 OS=Homo sapiens OX=9606 GN=RPS8 PE=1 SV=2 8.59 1748.7 - 8.44E+06 - - - -0.3619 - 1.321 0.284 - 28.6 2 2 0 -0.0004 11 0 0 0 1.51E+08 1.66E+08 - - - 2.3577 0.9999 221125_WJC_METTL3_EV_vs_WT_F06.07576.07576.2 9.96E-05 20-Aug K.ADTSQEIC[160.03]SPR.L "sp|P52948|NUP98_HUMAN,tr|A0A3B3ITD8|A0A3B3ITD8_HUMAN,tr|H7C3P6|H7C3P6_HUMAN" 3 1262.5561 0.81 77995 7576 2 1262.555146 632.2853 Nuclear pore complex protein Nup98-Nup96 OS=Homo sapiens OX=9606 GN=NUP98 PE=1 SV=4 4.37 1748.8 - 323387 - - - -0.7675 - 2.167 0.547 - 280.1 1 2 0 -0.001 11 0 0 0 2.61E+07 3.21E+07 - - - 5.1729 0.9973 221125_WJC_METTL3_EV_vs_WT_F06.07580.07580.2 0.000406 14-Aug R.SFTTTIHK[136.11].V sp|Q13257|MD2L1_HUMAN 1 941.5062 1.04 77997 7580 2 941.506515 471.7604 Mitotic spindle assembly checkpoint protein MAD2A OS=Homo sapiens OX=9606 GN=MAD2L1 PE=1 SV=1 8.49 1749.3 - 4.30E+06 - - - 0.3537 - 1.395 0.21 - 188.7 1 2 0 0.0003 8 0 0 0 1.56E+08 1.50E+08 - - - 1.5959 0.9854 221125_WJC_METTL3_EV_vs_WT_F06.07583.07583.2 0.0045 16-Aug K.GKNIQVVVR.C "sp|P52732|KIF11_HUMAN,tr|A0A7I2YQY4|A0A7I2YQY4_HUMAN,tr|A0A7I2V3V3|A0A7I2V3V3_HUMAN" 3 1011.6189 7.07 78000 7583 2 1011.616988 506.8167 Kinesin-like protein KIF11 OS=Homo sapiens OX=9606 GN=KIF11 PE=1 SV=2 11 1749.5 - 1.42E+06 - - - -1.9029 - 1.572 0.326 - 141.7 1 2 1 -0.0019 9 0 0 0 1.77E+07 2.50E+06 - - - 2.7569 0.9966 221125_WJC_METTL3_EV_vs_WT_F06.07586.07586.2 0.00037 14-Aug R.SFTTTIHK.V sp|Q13257|MD2L1_HUMAN 1 933.492 1.04 78001 7586 2 933.491199 467.7533 Mitotic spindle assembly checkpoint protein MAD2A OS=Homo sapiens OX=9606 GN=MAD2L1 PE=1 SV=1 8.49 1749.9 - 4.85E+06 - - - -0.8388 - 1.461 0.173 - 174.9 1 2 0 -0.0008 8 0 0 0 1.57E+08 1.50E+08 - - - 1.4619 0.9993 221125_WJC_METTL3_EV_vs_WT_F06.07587.07587.3 0.021 Dec-44 K.AMQR[166.11]PETAATLK[136.11].R sp|P82932|RT06_HUMAN 1 1333.7143 0.74 78002 7587 3 1333.712563 445.5787 "28S ribosomal protein S6, mitochondrial OS=Homo sapiens OX=9606 GN=MRPS6 PE=1 SV=3" 8.79 1750 - 901464 - - - -1.2949 - 1.696 0.328 - 103.4 1 2 0 -0.0017 12 0 0 0 3.70E+07 4.99E+07 - - - 3.6607 0.9997 221125_WJC_METTL3_EV_vs_WT_F06.07591.07591.2 8.40E-05 20-Nov R.EYNEDEDPAAR[166.11].R "sp|Q13123|RED_HUMAN,tr|D6RAY9|D6RAY9_HUMAN,tr|D6REL4|D6REL4_HUMAN,tr|E7EQZ7|E7EQZ7_HUMAN,tr|D6RCQ4|D6RCQ4_HUMAN" 5 1317.5349 1.54 78004 7591 2 1317.532307 659.7747 Protein Red OS=Homo sapiens OX=9606 GN=IK PE=1 SV=3 3.83 1750.6 - 675579 - - - -1.937 - 1.821 0.544 - 339.1 1 2 0 -0.0026 11 0 0 0 6.07E+07 3.93E+07 - - - 4.6797 0.9963 221125_WJC_METTL3_EV_vs_WT_F06.07596.07596.3 0.00346 Dec-36 K.LGVIEDHSNR.T "sp|Q58FF3|ENPLL_HUMAN,sp|P14625|ENPL_HUMAN,tr|A0A7P0T917|A0A7P0T917_HUMAN,tr|A0A7P0T823|A0A7P0T823_HUMAN,tr|A0A7P0TAE1|A0A7P0TAE1_HUMAN,tr|H0YIV0|H0YIV0_HUMAN,tr|A0A7P0TAY2|A0A7P0TAY2_HUMAN,tr|A0A087WT78|A0A087WT78_HUMAN,tr|A0A7P0TAT8|A0A7P0TAT8_HUMAN" 9 1138.5731 0.77 78006 7596 3 1138.568111 380.5316 Putative endoplasmin-like protein OS=Homo sapiens OX=9606 GN=HSP90B2P PE=5 SV=1 5.32 1751.3 - 1.04E+06 - - - -4.3686 - 2.181 0.292 - 131.3 1 2 0 -0.005 10 0 0 0 3.43E+07 4.43E+07 - - - 4.0714 0.9459 221125_WJC_METTL3_EV_vs_WT_F06.07602.07602.3 1.83 Sep-40 R.SNMSPHGLPAR[166.11].S "sp|Q13330|MTA1_HUMAN,tr|H0Y4T7|H0Y4T7_HUMAN,tr|E7ESY4|E7ESY4_HUMAN" 3 1175.5745 0.91 78010 7602 3 1175.576994 392.8654 Metastasis-associated protein MTA1 OS=Homo sapiens OX=9606 GN=MTA1 PE=1 SV=2 9.49 1752 - 811266 - - - 2.1249 - 1.584 0.124 - 75.1 1 2 0 0.0025 11 0 0 0 2.01E+07 2.22E+07 - - - 1.2284 0.998 221125_WJC_METTL3_EV_vs_WT_F06.07608.07608.2 0.179 18-Aug K.VAQPTITDNK.D "sp|P21333|FLNA_HUMAN,tr|Q60FE5|Q60FE5_HUMAN,tr|H0Y5F3|H0Y5F3_HUMAN" 3 1085.5717 1.15 78013 7608 2 1085.570894 543.7931 Filamin-A OS=Homo sapiens OX=9606 GN=FLNA PE=1 SV=4 5.81 1752.7 - 744390 - - - -0.7314 - 1.428 0.246 - 188.1 1 2 0 -0.0008 10 0 0 0 1.86E+07 1.62E+07 - - - 1.8522 0.9998 221125_WJC_METTL3_EV_vs_WT_F06.07611.07611.2 3.01E-06 20-Nov R.SDEGQLSPATR[166.11].G "sp|Q15149|PLEC_HUMAN,tr|E9PMV1|E9PMV1_HUMAN,tr|H0YDN1|H0YDN1_HUMAN" 3 1169.5552 1.75 78016 7611 2 1169.553774 585.7849 Plectin OS=Homo sapiens OX=9606 GN=PLEC PE=1 SV=3 4.37 1753.1 - 666216 - - - -1.2193 - 2.069 0.491 - 422.3 1 2 0 -0.0014 11 0 0 0 5.15E+07 2.93E+07 - - - 4.634 1 221125_WJC_METTL3_EV_vs_WT_F06.07613.07613.2 6.49E-07 14/22 K.VGGTSDVEVNEK[136.11].K "sp|P10809|CH60_HUMAN,tr|A0A7I2V2X6|A0A7I2V2X6_HUMAN,tr|A0A7I2YQK6|A0A7I2YQK6_HUMAN,tr|A0A7I2V599|A0A7I2V599_HUMAN" 4 1240.6027 1.4 78017 7613 2 1240.603677 621.3086 "60 kDa heat shock protein, mitochondrial OS=Homo sapiens OX=9606 GN=HSPD1 PE=1 SV=2" 4.14 1753.3 - 1.94E+06 - - - 0.819 - 2.975 0.629 - 515.3 1 2 0 0.001 12 0 0 0 2.11E+08 1.50E+08 - - - 6.5551 0.999 221125_WJC_METTL3_EV_vs_WT_F06.07615.07615.2 0.362 20-Aug R.NPPPNSDPNLR.R sp|Q96I24|FUBP3_HUMAN 1 1219.5945 2.47 78018 7615 2 1219.594098 610.8046 Far upstream element-binding protein 3 OS=Homo sapiens OX=9606 GN=FUBP3 PE=1 SV=2 5.84 1753.5 - 1.12E+06 - - - -0.3698 - 1.63 0.275 - 206.1 1 2 0 -0.0005 11 0 0 0 8.99E+07 3.63E+07 - - - 2.3937 0.9999 221125_WJC_METTL3_EV_vs_WT_F06.07616.07616.2 3.25E-05 22-Dec K.SLSEAPEDTSTR.G "sp|P41214|EIF2D_HUMAN,tr|Q5SY38|Q5SY38_HUMAN" 2 1291.5892 1.75 78019 7616 2 1291.588957 646.8019 Eukaryotic translation initiation factor 2D OS=Homo sapiens OX=9606 GN=EIF2D PE=1 SV=3 4.14 1753.6 - 829484 - - - -0.1796 - 2.101 0.535 - 454 1 2 0 -0.0002 12 0 0 0 3.05E+07 1.74E+07 - - - 4.9459 0.9981 221125_WJC_METTL3_EV_vs_WT_F06.07620.07620.2 0.024 18-Oct R.SISQSISGQK.- "sp|Q8WXI9|P66B_HUMAN,tr|A0A0U1RRM1|A0A0U1RRM1_HUMAN" 2 1033.5404 1.75 78021 7620 2 1033.54173 517.7775 Transcriptional repressor p66-beta OS=Homo sapiens OX=9606 GN=GATAD2B PE=1 SV=1 8.47 1754.1 - 1.14E+06 - - - 1.2984 - 1.674 0.233 - 266.3 1 2 0 0.0013 10 0 0 0 8.99E+08 5.13E+08 - - - 2.1996 0.9999 221125_WJC_METTL3_EV_vs_WT_F06.07621.07621.2 0.00186 22-Dec K.SLSEAPEDTSTR[166.11].G "sp|P41214|EIF2D_HUMAN,tr|Q5SY38|Q5SY38_HUMAN" 2 1301.5975 1.72 78022 7621 2 1301.597867 651.806 Eukaryotic translation initiation factor 2D OS=Homo sapiens OX=9606 GN=EIF2D PE=1 SV=3 4.14 1754.3 - 612656 - - - 0.3135 - 2.188 0.515 - 446 1 2 0 0.0004 12 0 0 0 3.00E+07 1.74E+07 - - - 4.9048 0.9947 221125_WJC_METTL3_EV_vs_WT_F06.07622.07622.3 0.0659 Aug-36 K.VQEFEHVNGR.W "sp|Q14839|CHD4_HUMAN,tr|A0A2R8Y4X2|A0A2R8Y4X2_HUMAN,tr|A0A2U3TZM0|A0A2U3TZM0_HUMAN,tr|A0A2R8Y5M9|A0A2R8Y5M9_HUMAN,tr|A0A2R8Y445|A0A2R8Y445_HUMAN,tr|A0A2R8YD40|A0A2R8YD40_HUMAN,tr|A0A2R8Y5J0|A0A2R8Y5J0_HUMAN,tr|A0A2R8Y425|A0A2R8Y425_HUMAN,tr|A0A2R8YFK9|A0A2R8YFK9_HUMAN,tr|A0A2R8Y8C1|A0A2R8Y8C1_HUMAN,tr|A0A0C4DGG9|A0A0C4DGG9_HUMAN,tr|A0A2R8YFD8|A0A2R8YFD8_HUMAN,tr|A0A2R8YDW2|A0A2R8YDW2_HUMAN,tr|A0A2R8Y7I0|A0A2R8Y7I0_HUMAN,tr|F5GWX5|F5GWX5_HUMAN,tr|A0A2R8YER1|A0A2R8YER1_HUMAN,tr|A0A2R8Y7M9|A0A2R8Y7M9_HUMAN,tr|A0A2R8Y521|A0A2R8Y521_HUMAN,tr|A0A2R8YDJ9|A0A2R8YDJ9_HUMAN,tr|A0A2R8Y212|A0A2R8Y212_HUMAN,tr|A0A2R8YE38|A0A2R8YE38_HUMAN" 21 1213.584 0.86 78023 7622 3 1213.583631 405.5353 Chromodomain-helicase-DNA-binding protein 4 OS=Homo sapiens OX=9606 GN=CHD4 PE=1 SV=2 5.4 1754.3 - 1.43E+06 - - - -0.2909 - 1.607 0.216 - 90.3 2 2 0 -0.0004 10 0 0 0 4.19E+07 4.90E+07 - - - 2.1941 0.9863 221125_WJC_METTL3_EV_vs_WT_F06.07624.07624.2 0.0498 18-Jul K.LQEVEC[160.03]EEQR.L "sp|Q13596|SNX1_HUMAN,tr|H0YK42|H0YK42_HUMAN" 2 1318.5823 1.16 78025 7624 2 1318.589582 660.2984 Sorting nexin-1 OS=Homo sapiens OX=9606 GN=SNX1 PE=1 SV=3 4.09 1754.6 - 239585 - - - 5.4998 - 1.57 0.37 - 99.5 1 2 0 0.0073 10 0 0 0 7.22E+06 6.22E+06 - - - 3.0306 0.9985 221125_WJC_METTL3_EV_vs_WT_F06.07629.07629.3 0.00155 Dec-36 K.LQNDFAEK[136.11]ER[166.11].K "sp|Q13948|CASP_HUMAN,sp|P39880|CUX1_HUMAN,tr|A0A2R8Y8D0|A0A2R8Y8D0_HUMAN,tr|A0A2R8Y852|A0A2R8Y852_HUMAN,tr|A0A2R8YDI1|A0A2R8YDI1_HUMAN" 5 1266.6323 1.73 78028 7629 3 1266.631774 423.2181 Protein CASP OS=Homo sapiens OX=9606 GN=CUX1 PE=1 SV=2 4.68 1755.2 - 865938 - - - -0.4429 - 2.243 0.291 - 165.1 1 2 1 -0.0006 10 0 0 0 3.07E+07 1.77E+07 - - - 4.1434 0.9999 221125_WJC_METTL3_EV_vs_WT_F06.07631.07631.2 2.22E-06 18-Dec K.HSTLVNDAYK.T "sp|Q8IWL3|HSC20_HUMAN,tr|B0QYH2|B0QYH2_HUMAN" 2 1146.5669 1.24 78030 7631 2 1146.568421 574.2907 Iron-sulfur cluster co-chaperone protein HscB OS=Homo sapiens OX=9606 GN=HSCB PE=1 SV=3 6.74 1755.4 - 904424 - - - 1.2943 - 2.268 0.573 - 322.8 1 2 0 0.0015 10 0 0 0 5.84E+07 4.72E+07 - - - 5.5585 0.9992 221125_WJC_METTL3_EV_vs_WT_F06.07632.07632.2 0.00241 16-Sep K.YTEQITNEK.L "sp|Q16718|NDUA5_HUMAN,tr|C9IZN5|C9IZN5_HUMAN,tr|H7BYD0|H7BYD0_HUMAN,tr|A0A087X1G1|A0A087X1G1_HUMAN,tr|F8WAS3|F8WAS3_HUMAN,tr|A0A7I2V2W4|A0A7I2V2W4_HUMAN,tr|A0A7I2V3L8|A0A7I2V3L8_HUMAN" 7 1124.535 1.21 78031 7632 2 1124.533954 563.2748 NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 5 OS=Homo sapiens OX=9606 GN=NDUFA5 PE=1 SV=3 4.53 1755.5 - 739518 - - - -0.9026 - 1.689 0.29 - 262.4 1 2 0 -0.001 9 0 0 0 3.70E+07 3.06E+07 - - - 2.699 1 221125_WJC_METTL3_EV_vs_WT_F06.07633.07633.2 1.21E-06 18/24 R.LAQDGAHVVVSSR[166.11].K "sp|Q9BTZ2|DHRS4_HUMAN,tr|F5GWZ1|F5GWZ1_HUMAN" 2 1347.7134 1.48 78032 7633 2 1347.714722 674.864 Dehydrogenase\reductase SDR family member 4 OS=Homo sapiens OX=9606 GN=DHRS4 PE=1 SV=3 6.74 1755.6 - 664891 - - - 0.9572 - 3.276 0.584 - 1620 1 2 0 0.0013 13 0 0 0 3.43E+08 2.32E+08 - - - 6.3995 1 221125_WJC_METTL3_EV_vs_WT_F06.07637.07637.2 3.32E-09 19/24 R.LAQDGAHVVVSSR.K "sp|Q9BTZ2|DHRS4_HUMAN,tr|F5GWZ1|F5GWZ1_HUMAN" 2 1337.7052 1.48 78034 7637 2 1337.706178 669.8599 Dehydrogenase\reductase SDR family member 4 OS=Homo sapiens OX=9606 GN=DHRS4 PE=1 SV=3 6.74 1756.2 - 1.97E+06 - - - 0.7595 - 3.386 0.531 - 1757.2 1 2 0 0.001 13 0 0 0 3.43E+08 2.32E+08 - - - 6.0929 0.9999 221125_WJC_METTL3_EV_vs_WT_F06.07638.07638.2 2.49E-06 18-Nov R.ESSNVVVTER.V sp|Q02413|DSG1_HUMAN 1 1118.5568 22.04 78035 7638 2 1118.556026 560.2857 Desmoglein-1 OS=Homo sapiens OX=9606 GN=DSG1 PE=1 SV=2 4.53 1756.3 - 1.45E+06 - - - -0.6625 - 2.276 0.563 - 498.4 1 2 0 -0.0007 10 0 0 0 2.65E+07 1.20E+06 - - - 5.4947 0.998 221125_WJC_METTL3_EV_vs_WT_F06.07639.07639.2 0.131 20-Sep R.QVAPGAPSAPR.R "sp|Q8ND56|LS14A_HUMAN,tr|A0A140TA76|A0A140TA76_HUMAN,tr|K7EMZ9|K7EMZ9_HUMAN" 3 1049.5618 1.25 78036 7639 2 1049.561369 525.7882 Protein LSM14 homolog A OS=Homo sapiens OX=9606 GN=LSM14A PE=1 SV=3 9.75 1756.3 - 817601 - - - -0.403 - 1.51 0.222 - 258.8 1 2 0 -0.0004 11 0 0 0 1.93E+07 1.54E+07 - - - 1.7954 0.9993 221125_WJC_METTL3_EV_vs_WT_F06.07644.07644.2 6.56E-06 22-Nov K.VVPTTDHIDTEK.L sp|O75663|TIPRL_HUMAN 1 1353.6776 0.34 78041 7644 2 1353.682073 677.8461 TIP41-like protein OS=Homo sapiens OX=9606 GN=TIPRL PE=1 SV=2 4.54 1757 - 317815 - - - 3.2969 - 2.025 0.522 - 401.1 1 2 0 0.0045 12 0 0 0 4.59E+06 1.35E+07 - - - 4.7516 0.9999 221125_WJC_METTL3_EV_vs_WT_F06.07645.07645.2 7.36E-05 18-Sep K.NYVQADEDC[160.03]R[166.11].H "sp|P42694|HELZ_HUMAN,tr|J3KT20|J3KT20_HUMAN,tr|J3QS41|J3QS41_HUMAN,tr|A0A075B6R3|A0A075B6R3_HUMAN" 4 1278.5174 3.3 78042 7645 2 1278.515777 640.266 Probable helicase with zinc finger domain OS=Homo sapiens OX=9606 GN=HELZ PE=1 SV=2 4.03 1757.1 - 268770 - - - -1.2968 - 1.911 0.609 - 334 1 2 0 -0.0017 10 0 0 0 9.40E+06 2.85E+06 - - - 5.3463 0.9999 221125_WJC_METTL3_EV_vs_WT_F06.07647.07647.3 4.24E-05 13/36 K.LGVIEDHSNR[166.11].T "sp|Q58FF3|ENPLL_HUMAN,sp|P14625|ENPL_HUMAN,tr|A0A7P0T917|A0A7P0T917_HUMAN,tr|A0A7P0T823|A0A7P0T823_HUMAN,tr|A0A7P0TAE1|A0A7P0TAE1_HUMAN,tr|H0YIV0|H0YIV0_HUMAN,tr|A0A7P0TAY2|A0A7P0TAY2_HUMAN,tr|A0A087WT78|A0A087WT78_HUMAN,tr|A0A7P0TAT8|A0A7P0TAT8_HUMAN" 9 1148.5814 0.78 78043 7647 3 1148.580438 383.8677 Putative endoplasmin-like protein OS=Homo sapiens OX=9606 GN=HSP90B2P PE=5 SV=1 5.32 1757.3 - 1.51E+06 - - - -0.7984 - 2.821 0.379 - 171.1 1 2 0 -0.0009 10 0 0 0 3.44E+07 4.44E+07 - - - 5.794 0.9997 221125_WJC_METTL3_EV_vs_WT_F06.07649.07649.2 0.00343 16-Aug K.ITITNDQNR[166.11].L "sp|P11021|BIP_HUMAN,tr|A0A7P0TB36|A0A7P0TB36_HUMAN,tr|A0A7P0TAI0|A0A7P0TAI0_HUMAN" 3 1083.5548 0.58 78044 7649 2 1083.555435 542.7847 Endoplasmic reticulum chaperone BiP OS=Homo sapiens OX=9606 GN=HSPA5 PE=1 SV=2 5.84 1757.6 - 2.87E+06 - - - 0.5805 - 1.694 0.42 - 222.3 1 2 0 0.0006 9 0 0 0 3.52E+08 6.04E+08 - - - 3.6678 0.9972 221125_WJC_METTL3_EV_vs_WT_F06.07650.07650.2 1.17E-05 14/18 K.HSTLVNDAYK[136.11].T "sp|Q8IWL3|HSC20_HUMAN,tr|B0QYH2|B0QYH2_HUMAN" 2 1154.5811 1.14 78045 7650 2 1154.584527 578.2978 Iron-sulfur cluster co-chaperone protein HscB OS=Homo sapiens OX=9606 GN=HSCB PE=1 SV=3 6.74 1757.6 - 1.66E+06 - - - 2.9361 - 2.179 0.213 - 437.7 1 2 0 0.0034 10 0 0 0 4.78E+07 4.18E+07 - - - 2.7872 0.9979 221125_WJC_METTL3_EV_vs_WT_F06.07652.07652.2 0.00905 16-Aug R.QFTSSSSIK.G sp|Q04695|K1C17_HUMAN 1 983.4924 200.33 78047 7652 2 983.493044 492.7535 "Keratin, type I cytoskeletal 17 OS=Homo sapiens OX=9606 GN=KRT17 PE=1 SV=2" 8.75 1757.7 - 1.51E+06 - - - 0.6802 - 1.366 0.26 - 236.8 1 2 0 0.0007 9 0 0 0 3.98E+07 1.99E+05 - - - 1.8635 1 221125_WJC_METTL3_EV_vs_WT_F06.07656.07656.2 2.61E-06 20-Dec K.C[160.03]SEC[160.03]GTAFGQK[136.11].K sp|Q15072|OZF_HUMAN 1 1251.5104 0.15 78051 7656 2 1251.506276 626.7625 Zinc finger protein OZF OS=Homo sapiens OX=9606 GN=ZNF146 PE=1 SV=2 5.99 1758.2 - 702097 - - - -3.2617 - 2.318 0.622 - 662.5 1 2 0 -0.0041 11 0 0 0 1.45E+06 9.76E+06 - - - 5.9081 0.9999 221125_WJC_METTL3_EV_vs_WT_F06.07657.07657.2 2.79E-06 18-Sep K.NYVQADEDC[160.03]R.H "sp|P42694|HELZ_HUMAN,tr|J3KT20|J3KT20_HUMAN,tr|J3QS41|J3QS41_HUMAN,tr|A0A075B6R3|A0A075B6R3_HUMAN" 4 1268.5092 3.3 78052 7657 2 1268.509338 635.2619 Probable helicase with zinc finger domain OS=Homo sapiens OX=9606 GN=HELZ PE=1 SV=2 4.03 1758.3 - 691270 - - - 0.1364 - 1.913 0.628 - 324.2 1 2 0 0.0002 10 0 0 0 9.40E+06 2.85E+06 - - - 5.49 0.9997 221125_WJC_METTL3_EV_vs_WT_F06.07663.07663.3 1.41E-05 14/44 K.VVPTTDHIDTEK[136.11].L sp|O75663|TIPRL_HUMAN 1 1361.6918 0.69 78056 7663 3 1361.690608 454.9045 TIP41-like protein OS=Homo sapiens OX=9606 GN=TIPRL PE=1 SV=2 4.54 1759.1 - 1.62E+07 - - - -0.8827 - 1.983 0.335 - 104.5 1 2 0 -0.0012 12 0 0 0 7.93E+07 1.15E+08 - - - 4.1722 0.9993 221125_WJC_METTL3_EV_vs_WT_F06.07664.07664.2 0.0241 16-Jul K.ITITNDQNR.L "sp|P11021|BIP_HUMAN,tr|A0A7P0TB36|A0A7P0TB36_HUMAN,tr|A0A7P0TAI0|A0A7P0TAI0_HUMAN" 3 1073.5465 0.58 78057 7664 2 1073.546637 537.7805 Endoplasmic reticulum chaperone BiP OS=Homo sapiens OX=9606 GN=HSPA5 PE=1 SV=2 5.84 1759.2 - 4.74E+06 - - - 0.0941 - 1.554 0.325 - 134.9 1 2 0 0.0001 9 0 0 0 3.52E+08 6.04E+08 - - - 2.7168 0.9999 221125_WJC_METTL3_EV_vs_WT_F06.07665.07665.3 0.000391 17/44 R.IGRPMVASPNQR.H tr|H7C0V5|H7C0V5_HUMAN 1 1324.7034 1.17 78058 7665 3 1324.705724 442.5751 ANKHD1-EIF4EBP3 readthrough (Fragment) OS=Homo sapiens OX=9606 GN=ANKHD1-EIF4EBP3 PE=4 SV=1 12 1759.3 - 1.75E+06 - - - 1.7634 - 2.812 0.351 - 273.8 1 2 0 0.0023 12 0 0 0 7.79E+07 6.66E+07 - - - 5.3185 0.9996 221125_WJC_METTL3_EV_vs_WT_F06.07666.07666.2 0.000745 14-Jul K.GNFHAVYR.D sp|P05109|S10A8_HUMAN 1 962.4722 999 78059 7666 2 962.472778 482.2434 Protein S100-A8 OS=Homo sapiens OX=9606 GN=S100A8 PE=1 SV=1 8.75 1759.4 - 1.49E+06 - - - 0.5496 - 1.535 0.405 - 271 1 2 0 0.0005 8 0 0 0 2.12E+07 0.00E+00 - - - 3.3246 0.999 221125_WJC_METTL3_EV_vs_WT_F06.07667.07667.2 0.000114 18-Nov K.YNHIDESEMK[136.11].K "sp|Q92598|HS105_HUMAN,tr|Q5TBM3|Q5TBM3_HUMAN,tr|A0A0A0MSM0|A0A0A0MSM0_HUMAN" 3 1272.5536 0.08 78060 7667 2 1272.557216 637.2841 Heat shock protein 105 kDa OS=Homo sapiens OX=9606 GN=HSPH1 PE=1 SV=1 4.65 1759.5 - 1.25E+06 - - - 2.84 - 2.284 0.344 - 484.9 1 2 0 0.0036 10 0 0 0 2.98E+06 3.57E+07 - - - 3.8861 1 221125_WJC_METTL3_EV_vs_WT_F06.07668.07668.2 1.02E-10 17/20 A.QDGAHVVVSSR[166.11].K "sp|Q9BTZ2|DHRS4_HUMAN,tr|F5GWZ1|F5GWZ1_HUMAN" 2 1163.5923 2.16 78061 7668 2 1163.597463 582.8034 Dehydrogenase\reductase SDR family member 4 OS=Homo sapiens OX=9606 GN=DHRS4 PE=1 SV=3 6.74 1759.6 - 1.24E+06 - - - 4.4767 - 2.667 0.643 - 1279.4 1 1 0 0.0052 11 0 0 0 5.52E+07 2.55E+07 - - - 6.4423 0.9935 221125_WJC_METTL3_EV_vs_WT_F06.07669.07669.2 0.0971 14-Jun K.HAEYTLER.G "sp|Q8TEK3|DOT1L_HUMAN,tr|C9JH95|C9JH95_HUMAN" 2 1017.488 1.04 78062 7669 2 1017.488005 509.7513 "Histone-lysine N-methyltransferase, H3 lysine-79 specific OS=Homo sapiens OX=9606 GN=DOT1L PE=1 SV=3" 5.4 1759.8 - 725607 - - - 0.0452 - 1.18 0.186 - 90 1 2 0 0 8 0 0 0 1.59E+07 1.53E+07 - - - 0.914 1 221125_WJC_METTL3_EV_vs_WT_F06.07670.07670.2 1.28E-05 16/26 L.ALTQSVGGDSSADR[166.11].L "sp|Q86U44|MTA70_HUMAN,tr|H0YFV6|H0YFV6_HUMAN" 2 1372.6458 0.01 78063 7670 2 1372.647089 687.3302 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 4.21 1759.9 - 514841 - - - 0.9347 - 2.79 0.558 - 863 1 1 0 0.0013 14 0 0 0 8.21E+06 5.81E+08 - - - 5.7368 0.9975 221125_WJC_METTL3_EV_vs_WT_F06.07671.07671.2 0.00125 26-Sep K.VANPSSDADGQSLK[136.11].V sp|Q8IWI9|MGAP_HUMAN 1 1395.6721 1.84 78064 7671 2 1395.667295 698.8433 MAX gene-associated protein OS=Homo sapiens OX=9606 GN=MGA PE=1 SV=4 4.21 1760 - 223386 - - - -3.4693 - 1.706 0.393 - 116.1 1 2 0 -0.0048 14 0 0 0 1.33E+07 7.26E+06 - - - 3.2826 0.9999 221125_WJC_METTL3_EV_vs_WT_F06.07674.07674.2 8.97E-06 18-Sep R.SISQSISGQK[136.11].- "sp|Q8WXI9|P66B_HUMAN,tr|A0A0U1RRM1|A0A0U1RRM1_HUMAN" 2 1041.5546 1.75 78065 7674 2 1041.554683 521.7846 Transcriptional repressor p66-beta OS=Homo sapiens OX=9606 GN=GATAD2B PE=1 SV=1 8.47 1760.5 - 2.52E+07 - - - 0.0912 - 1.933 0.5 - 182.2 1 2 0 0.0001 10 0 0 0 8.99E+08 5.13E+08 - - - 4.5736 0.9939 221125_WJC_METTL3_EV_vs_WT_F06.07675.07675.3 0.0593 Sep-36 R.VLNTNIDGR[166.11]R[166.11].K "sp|P62269|RS18_HUMAN,tr|A0A0G2JQH2|A0A0G2JQH2_HUMAN,tr|Q5GGW2|Q5GGW2_HUMAN" 3 1176.6478 0.92 78066 7675 3 1176.647931 393.2232 40S ribosomal protein S18 OS=Homo sapiens OX=9606 GN=RPS18 PE=1 SV=3 9.57 1760.5 - 2.54E+06 - - - 0.1037 - 1.595 0.198 - 116.9 1 2 0 0.0001 10 0 0 0 1.18E+08 1.28E+08 - - - 2.1109 0.9998 221125_WJC_METTL3_EV_vs_WT_F06.07676.07676.3 0.000843 13/40 R.DPNDVRPIQAR.L "sp|Q9H307|PININ_HUMAN,tr|G3V5F0|G3V5F0_HUMAN,tr|G3V579|G3V579_HUMAN" 3 1279.6633 1.97 78067 7676 3 1279.663157 427.5617 Pinin OS=Homo sapiens OX=9606 GN=PNN PE=1 SV=5 5.96 1760.6 - 1.89E+06 - - - -0.1094 - 1.765 0.379 - 180.7 1 2 0 -0.0001 11 0 0 0 6.79E+07 3.44E+07 - - - 4.3795 0.9999 221125_WJC_METTL3_EV_vs_WT_F06.07677.07677.3 2.67E-06 14/40 R.DPNDVR[166.11]PIQAR[166.11].L "sp|Q9H307|PININ_HUMAN,tr|G3V5F0|G3V5F0_HUMAN,tr|G3V579|G3V579_HUMAN" 3 1299.6798 2.02 78068 7677 3 1299.679036 434.2339 Pinin OS=Homo sapiens OX=9606 GN=PNN PE=1 SV=5 5.96 1760.7 - 1.88E+06 - - - -0.6163 - 2.425 0.425 - 317.7 1 2 0 -0.0008 11 0 0 0 6.73E+07 3.34E+07 - - - 5.7946 0.9933 221125_WJC_METTL3_EV_vs_WT_F06.07679.07679.3 0.0304 May-36 K.YNHIDESEMK.K "sp|Q92598|HS105_HUMAN,tr|Q5TBM3|Q5TBM3_HUMAN,tr|A0A0A0MSM0|A0A0A0MSM0_HUMAN" 3 1264.5394 0.15 78070 7679 3 1264.538231 422.5204 Heat shock protein 105 kDa OS=Homo sapiens OX=9606 GN=HSPH1 PE=1 SV=1 4.65 1760.8 - 1.36E+06 - - - -0.926 - 1.113 0.287 - 23.9 1 2 0 -0.0012 10 0 0 0 2.02E+07 1.36E+08 - - - 2.0521 0.9981 221125_WJC_METTL3_EV_vs_WT_F06.07681.07681.2 6.82E-05 22-Nov R.YSNSEVVTGSGR[166.11].Q "sp|Q7L576|CYFP1_HUMAN,tr|A0A0G2JR96|A0A0G2JR96_HUMAN,tr|A0A0G2JQT1|A0A0G2JQT1_HUMAN" 3 1264.5923 0.22 78072 7681 2 1264.598165 633.3034 Cytoplasmic FMR1-interacting protein 1 OS=Homo sapiens OX=9606 GN=CYFIP1 PE=1 SV=1 6 1761.1 - 816965 - - - 4.6268 - 1.987 0.534 - 220.8 1 2 0 0.0059 12 0 0 0 3.96E+06 1.82E+07 - - - 4.7899 0.9997 221125_WJC_METTL3_EV_vs_WT_F06.07683.07683.2 0.000669 20-Sep K.EFSNSNNLDNK.S "sp|O60315|ZEB2_HUMAN,tr|U3KQ51|U3KQ51_HUMAN,tr|A0JP08|A0JP08_HUMAN,tr|A0A6Q8PH34|A0A6Q8PH34_HUMAN,tr|A0A1B0GW50|A0A1B0GW50_HUMAN,tr|A0A1B0GV02|A0A1B0GV02_HUMAN,tr|A0A1B0GVV8|A0A1B0GVV8_HUMAN" 7 1280.5633 31.74 78074 7683 2 1280.561583 641.2889 Zinc finger E-box-binding homeobox 2 OS=Homo sapiens OX=9606 GN=ZEB2 PE=1 SV=1 4.37 1761.3 - 318466 - - - -1.3478 - 1.623 0.505 - 146.7 1 2 0 -0.0017 11 0 0 0 4.24E+06 1.33E+05 - - - 4.0805 1 221125_WJC_METTL3_EV_vs_WT_F06.07688.07688.2 5.54E-07 17/22 L.AQDGAHVVVSSR[166.11].K "sp|Q9BTZ2|DHRS4_HUMAN,tr|F5GWZ1|F5GWZ1_HUMAN" 2 1234.6294 2.08 78077 7688 2 1234.630443 618.322 Dehydrogenase\reductase SDR family member 4 OS=Homo sapiens OX=9606 GN=DHRS4 PE=1 SV=3 6.79 1761.9 - 2.84E+06 - - - 0.8707 - 3.201 0.641 - 1425.9 1 1 0 0.0011 12 0 0 0 6.98E+07 3.36E+07 - - - 6.8364 0.9921 221125_WJC_METTL3_EV_vs_WT_F06.07689.07689.3 1.15 Aug-36 R.VLNTNIDGRR.K "sp|P62269|RS18_HUMAN,tr|A0A0G2JQH2|A0A0G2JQH2_HUMAN,tr|Q5GGW2|Q5GGW2_HUMAN" 3 1156.6313 0.92 78078 7689 3 1156.630114 386.551 40S ribosomal protein S18 OS=Homo sapiens OX=9606 GN=RPS18 PE=1 SV=3 9.57 1761.9 - 2.99E+06 - - - -0.9986 - 1.533 0.194 - 103.1 1 2 0 -0.0012 10 0 0 0 1.17E+08 1.27E+08 - - - 1.9503 0.9848 221125_WJC_METTL3_EV_vs_WT_F06.07696.07696.2 0.445 20-Jun R.AVDFLAANESR[166.11].V sp|Q9Y2U8|MAN1_HUMAN 1 1201.5967 1.01 78085 7696 2 1201.598352 601.8056 Inner nuclear membrane protein Man1 OS=Homo sapiens OX=9606 GN=LEMD3 PE=1 SV=2 4.37 1762.7 - 681755 - - - 1.399 - 1.274 0.173 - 54.7 5 2 0 0.0017 11 0 0 0 1.32E+07 1.31E+07 - - - 0.6611 0.9495 221125_WJC_METTL3_EV_vs_WT_F06.07699.07699.2 3.94 18-Jul R.VLNTNIDGR[166.11]R[166.11].K "sp|P62269|RS18_HUMAN,tr|A0A0G2JQH2|A0A0G2JQH2_HUMAN,tr|Q5GGW2|Q5GGW2_HUMAN" 3 1176.6478 1.02 78088 7699 2 1176.647229 589.3312 40S ribosomal protein S18 OS=Homo sapiens OX=9606 GN=RPS18 PE=1 SV=3 9.57 1763.1 - 613295 - - - -0.4929 - 1.051 0.082 - 68.5 3 2 0 -0.0006 10 0 0 0 2.11E+07 2.07E+07 - - - -0.4278 0.9999 221125_WJC_METTL3_EV_vs_WT_F06.07704.07704.3 0.00171 Nov-44 R.VTSGVKPASFDK.V "sp|Q9H4A3|WNK1_HUMAN,tr|F5GWT4|F5GWT4_HUMAN" 2 1234.6558 2.12 78091 7704 3 1234.654884 412.5592 Serine\threonine-protein kinase WNK1 OS=Homo sapiens OX=9606 GN=WNK1 PE=1 SV=2 8.56 1763.6 - 2.79E+06 - - - -0.703 - 2.245 0.368 - 101.5 1 2 0 -0.0009 12 0 0 0 1.02E+08 4.81E+07 - - - 4.8842 0.977 221125_WJC_METTL3_EV_vs_WT_F06.07705.07705.3 0.554 Nov-44 R.VTSGVK[136.11]PASFDK[136.11].V "sp|Q9H4A3|WNK1_HUMAN,tr|F5GWT4|F5GWT4_HUMAN" 2 1250.6842 2.24 78092 7705 3 1250.684725 417.902 Serine\threonine-protein kinase WNK1 OS=Homo sapiens OX=9606 GN=WNK1 PE=1 SV=2 8.56 1763.7 - 1.75E+06 - - - 0.4581 - 1.809 0.101 - 144.6 1 2 0 0.0006 12 0 0 0 1.12E+08 4.99E+07 - - - 1.309 0.9842 221125_WJC_METTL3_EV_vs_WT_F06.07706.07706.2 0.176 18-Nov K.AYGELPEHAK.L "sp|O14602|IF1AY_HUMAN,sp|P47813|IF1AX_HUMAN,tr|A6NJH9|A6NJH9_HUMAN,tr|X6RAC9|X6RAC9_HUMAN" 4 1113.5455 0.54 78093 7706 2 1113.538824 557.78 "Eukaryotic translation initiation factor 1A, Y-chromosomal OS=Homo sapiens OX=9606 GN=EIF1AY PE=1 SV=4" 5.4 1763.7 - 1.47E+06 - - - -5.9719 - 1.625 0.38 - 318.1 1 2 0 -0.0066 10 0 0 0 3.17E+07 5.82E+07 - - - 3.2008 0.9997 221125_WJC_METTL3_EV_vs_WT_F06.07707.07707.2 0.00368 14/14 K.HQTLELEK.E "sp|P28358|HXD10_HUMAN,sp|P31260|HXA10_HUMAN,sp|P31269|HXA9_HUMAN,sp|Q9NYD6|HXC10_HUMAN,tr|A0A669K9T0|A0A669K9T0_HUMAN,tr|A0A669KBC8|A0A669KBC8_HUMAN,tr|D6RAR5|D6RAR5_HUMAN" 7 996.524 1.43 78094 7707 2 996.526286 499.2693 Homeobox protein Hox-D10 OS=Homo sapiens OX=9606 GN=HOXD10 PE=1 SV=2 5.4 1763.9 - 1.17E+06 - - - 2.2839 - 2.612 0.417 - 701.7 1 2 0 0.0023 8 0 0 0 2.24E+07 1.57E+07 - - - 5.0159 0.98 221125_WJC_METTL3_EV_vs_WT_F06.07708.07708.2 5.2 14-Aug K.WR[166.11]EEQMER[166.11].L "sp|P09496|CLCA_HUMAN,tr|F8WF69|F8WF69_HUMAN" 2 1182.5355 0.4 78095 7708 2 1182.534471 592.275 Clathrin light chain A OS=Homo sapiens OX=9606 GN=CLTA PE=1 SV=1 4.79 1764 - 780807 - - - -0.8541 - 1.75 0.168 - 128.1 1 2 1 -0.001 8 0 0 0 5.25E+06 1.30E+07 - - - 1.9693 0.9926 221125_WJC_METTL3_EV_vs_WT_F06.07712.07712.2 0.0418 16-Sep R.R[166.11]SSLVITTK[136.11].L "sp|Q13303|KCAB2_HUMAN,sp|Q14722|KCAB1_HUMAN,tr|C9JBV8|C9JBV8_HUMAN,tr|A0A087X1P8|A0A087X1P8_HUMAN,tr|A0A590UJJ4|A0A590UJJ4_HUMAN,tr|Q5TG78|Q5TG78_HUMAN,tr|A0A590UJY1|A0A590UJY1_HUMAN,tr|A0A590UJB8|A0A590UJB8_HUMAN,tr|C9JQ60|C9JQ60_HUMAN,tr|Q5TG84|Q5TG84_HUMAN,tr|F8W6W4|F8W6W4_HUMAN,tr|Q5TG81|Q5TG81_HUMAN,tr|A0A5F9UN28|A0A5F9UN28_HUMAN,tr|A0A590UJU1|A0A590UJU1_HUMAN,tr|A0A590UJB6|A0A590UJB6_HUMAN,tr|B7Z8E5|B7Z8E5_HUMAN" 16 1021.6251 1.84 78097 7712 2 1021.626569 511.8198 Voltage-gated potassium channel subunit beta-2 OS=Homo sapiens OX=9606 GN=KCNAB2 PE=1 SV=2 11 1764.5 - 957061 - - - 1.4722 - 1.824 0.056 - 369.3 1 2 0 0.0015 9 0 0 0 3.79E+07 2.06E+07 - - - 1.193 0.9998 221125_WJC_METTL3_EV_vs_WT_F06.07713.07713.2 0.000361 16-Oct K.QDSGHLDLR[166.11].N "sp|Q86U44|MTA70_HUMAN,tr|B4E349|B4E349_HUMAN,tr|F5H6D8|F5H6D8_HUMAN,tr|B4DTN4|B4DTN4_HUMAN" 4 1049.5129 0.03 78098 7713 2 1049.513464 525.7637 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 5.21 1764.6 - 2.26E+06 - - - 0.4983 - 2.003 0.393 - 298 1 2 0 0.0005 9 0 0 0 3.85E+09 1.53E+11 - - - 3.9532 0.9989 221125_WJC_METTL3_EV_vs_WT_F06.07714.07714.2 0.113 16-Aug R.RSSLVITTK.L "sp|Q13303|KCAB2_HUMAN,sp|Q14722|KCAB1_HUMAN,tr|C9JBV8|C9JBV8_HUMAN,tr|A0A087X1P8|A0A087X1P8_HUMAN,tr|A0A590UJJ4|A0A590UJJ4_HUMAN,tr|Q5TG78|Q5TG78_HUMAN,tr|A0A590UJY1|A0A590UJY1_HUMAN,tr|A0A590UJB8|A0A590UJB8_HUMAN,tr|C9JQ60|C9JQ60_HUMAN,tr|Q5TG84|Q5TG84_HUMAN,tr|F8W6W4|F8W6W4_HUMAN,tr|Q5TG81|Q5TG81_HUMAN,tr|A0A5F9UN28|A0A5F9UN28_HUMAN,tr|A0A590UJU1|A0A590UJU1_HUMAN,tr|A0A590UJB6|A0A590UJB6_HUMAN,tr|B7Z8E5|B7Z8E5_HUMAN" 16 1003.6026 1.81 78099 7714 2 1003.602202 502.8086 Voltage-gated potassium channel subunit beta-2 OS=Homo sapiens OX=9606 GN=KCNAB2 PE=1 SV=2 11 1764.7 - 1.63E+06 - - - -0.3916 - 1.559 0.271 - 273.5 1 2 0 -0.0004 9 0 0 0 3.79E+07 2.10E+07 - - - 2.3271 0.9896 221125_WJC_METTL3_EV_vs_WT_F06.07718.07718.2 0.000234 26-Oct L.ALTQSVGGDSSADR.L "sp|Q86U44|MTA70_HUMAN,tr|H0YFV6|H0YFV6_HUMAN" 2 1362.6375 0.01 78103 7718 2 1362.635942 682.326 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 4.21 1765.2 - 279571 - - - -1.1698 - 2.26 0.484 - 302.6 1 1 0 -0.0016 14 0 0 0 8.21E+06 5.77E+08 - - - 4.6614 0.9999 221125_WJC_METTL3_EV_vs_WT_F06.07721.07721.2 0.032 15/18 K.KIEQELTAAK.K sp|Q9H444|CHM4B_HUMAN 1 1129.6343 2.18 78104 7721 2 1129.633806 565.8244 Charged multivesicular body protein 4b OS=Homo sapiens OX=9606 GN=CHMP4B PE=1 SV=1 6.14 1765.6 - 1.93E+06 - - - -0.4276 - 2.857 0.384 - 688.7 1 2 0 -0.0005 10 0 0 0 3.58E+07 1.64E+07 - - - 4.8073 0.8853 221125_WJC_METTL3_EV_vs_WT_F06.07722.07722.3 0.0553 Nov-44 N.IAHGNSSIIADR[166.11].L "sp|P11586|C1TC_HUMAN,tr|F5H2F4|F5H2F4_HUMAN,tr|V9GZ78|V9GZ78_HUMAN,tr|V9GYY3|V9GYY3_HUMAN,tr|A0A494C1T2|A0A494C1T2_HUMAN" 5 1262.6607 3.24 78105 7722 3 1262.661407 421.8942 "C-1-tetrahydrofolate synthase, cytoplasmic OS=Homo sapiens OX=9606 GN=MTHFD1 PE=1 SV=4" 6.74 1765.7 - 1.36E+06 - - - 0.5853 - 1.606 0.297 - 242.7 1 1 0 0.0007 12 0 0 0 6.48E+07 2.00E+07 - - - 3.1642 0.999 221125_WJC_METTL3_EV_vs_WT_F06.07725.07725.2 0.036 14-Sep R.K[136.11]DNQFLAR[166.11].M sp|P78316|NOP14_HUMAN 1 1008.5471 0.85 78108 7725 2 1008.546029 505.2809 Nucleolar protein 14 OS=Homo sapiens OX=9606 GN=NOP14 PE=1 SV=3 8.75 1766 - 590226 - - - -1.1105 - 1.565 0.297 - 274.9 1 2 0 -0.0011 8 0 0 0 1.13E+07 1.33E+07 - - - 2.5851 0.9701 221125_WJC_METTL3_EV_vs_WT_F06.07734.07734.2 3.50E-05 14/24 L.SLGSNSTVTASTR.S "sp|Q14157|UBP2L_HUMAN,tr|F8W726|F8W726_HUMAN,tr|H7C2T8|H7C2T8_HUMAN,tr|H0Y5H6|H0Y5H6_HUMAN" 4 1279.6368 2.06 78115 7734 2 1279.633174 640.8257 Ubiquitin-associated protein 2-like OS=Homo sapiens OX=9606 GN=UBAP2L PE=1 SV=2 9.47 1766.8 - 619779 - - - -2.8399 - 2.322 0.479 - 517.8 1 1 0 -0.0036 13 0 0 0 4.67E+06 2.27E+06 - - - 4.7399 0.9743 221125_WJC_METTL3_EV_vs_WT_F06.07743.07743.2 0.564 14-Oct Q.DSGHLDLR[166.11].N "sp|Q86U44|MTA70_HUMAN,tr|B4E349|B4E349_HUMAN,tr|F5H6D8|F5H6D8_HUMAN,tr|B4DTN4|B4DTN4_HUMAN" 4 921.4544 0.03 78121 7743 2 921.453639 461.7345 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 5.21 1767.9 - 5.33E+07 - - - -0.7868 - 2.136 0.262 - 392.8 1 1 0 -0.0007 8 0 0 0 7.26E+08 2.86E+10 - - - 3.2648 0.8996 221125_WJC_METTL3_EV_vs_WT_F06.07749.07749.2 0.738 12-Aug D.SGHLDLR[166.11].N "sp|Q86U44|MTA70_HUMAN,tr|D6R9M9|D6R9M9_HUMAN,tr|B4E349|B4E349_HUMAN,tr|F5H6D8|F5H6D8_HUMAN,tr|B4DTN4|B4DTN4_HUMAN,tr|D6R9X6|D6R9X6_HUMAN" 6 806.4274 0.03 78125 7749 2 806.426674 404.221 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 6.46 1768.5 - 6.58E+07 - - - -0.9263 - 1.415 0.248 - 314.5 1 1 0 -0.0007 7 0 0 0 4.68E+08 1.86E+10 - - - 1.9724 0.9944 221125_WJC_METTL3_EV_vs_WT_F06.07757.07757.2 0.0444 18-Sep K.SNQQNLGTIK[136.11].C "sp|P23921|RIR1_HUMAN,tr|E9PL69|E9PL69_HUMAN" 2 1109.592 0.44 78132 7757 2 1109.595056 555.8033 Ribonucleoside-diphosphate reductase large subunit OS=Homo sapiens OX=9606 GN=RRM1 PE=1 SV=1 8.47 1769.3 - 3.32E+06 - - - 2.7217 - 1.579 0.233 - 209.9 1 2 0 0.003 10 0 0 0 1.84E+07 4.20E+07 - - - 2.036 0.9999 221125_WJC_METTL3_EV_vs_WT_F06.07759.07759.2 0.000278 16-Oct K.QDSGHLDLR.N "sp|Q86U44|MTA70_HUMAN,tr|B4E349|B4E349_HUMAN,tr|F5H6D8|F5H6D8_HUMAN,tr|B4DTN4|B4DTN4_HUMAN" 4 1039.5047 0.03 78133 7759 2 1039.504747 520.7596 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 5.21 1769.6 - 2.09E+07 - - - 0.0731 - 2.113 0.494 - 303 1 2 0 0.0001 9 0 0 0 3.84E+09 1.53E+11 - - - 4.854 0.9759 221125_WJC_METTL3_EV_vs_WT_F06.07763.07763.2 0.00724 14-Nov Q.DSGHLDLR.N "sp|Q86U44|MTA70_HUMAN,tr|B4E349|B4E349_HUMAN,tr|F5H6D8|F5H6D8_HUMAN,tr|B4DTN4|B4DTN4_HUMAN" 4 911.4461 0.03 78136 7763 2 911.445096 456.7303 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 5.21 1769.7 - 3.50E+06 - - - -1.095 - 2.17 0.283 - 476 1 1 0 -0.001 8 0 0 0 7.26E+08 2.86E+10 - - - 3.4675 0.7786 221125_WJC_METTL3_EV_vs_WT_F06.07765.07765.2 1.01 12-Sep D.SGHLDLR.N "sp|Q86U44|MTA70_HUMAN,tr|D6R9M9|D6R9M9_HUMAN,tr|B4E349|B4E349_HUMAN,tr|F5H6D8|F5H6D8_HUMAN,tr|B4DTN4|B4DTN4_HUMAN,tr|D6R9X6|D6R9X6_HUMAN" 6 796.4192 0.02 78138 7765 2 796.418724 399.2169 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 6.46 1770 - 3.12E+06 - - - -0.5361 - 1.466 0.124 - 350.4 1 1 0 -0.0004 7 0 0 0 4.62E+08 1.86E+10 - - - 1.1688 0.9986 221125_WJC_METTL3_EV_vs_WT_F06.07767.07767.2 0.000374 22-Oct K.INQMATAPDSQR[166.11].L sp|Q9UQE7|SMC3_HUMAN 1 1340.6382 0.25 78140 7767 2 1340.635438 671.3264 Structural maintenance of chromosomes protein 3 OS=Homo sapiens OX=9606 GN=SMC3 PE=1 SV=2 5.84 1770.2 - 2.23E+06 - - - -2.0736 - 2.319 0.233 - 426.3 2 2 0 -0.0028 12 0 0 0 2.32E+07 9.15E+07 - - - 2.8398 0.9998 221125_WJC_METTL3_EV_vs_WT_F06.07795.07795.2 1.11E-05 13/20 K.LTNQNDELEEK.V "sp|P82094|TMF1_HUMAN,tr|A0A2R8Y7M0|A0A2R8Y7M0_HUMAN" 2 1331.6205 1.35 78155 7795 2 1331.621703 666.8175 TATA element modulatory factor OS=Homo sapiens OX=9606 GN=TMF1 PE=1 SV=2 4 1773.4 - 3.60E+06 - - - 0.9117 - 2.398 0.463 - 791.9 1 2 0 0.0012 11 0 0 0 1.33E+08 9.88E+07 - - - 4.8264 0.9847 221125_WJC_METTL3_EV_vs_WT_F06.07811.07811.2 0.74 17/28 S.GGGGGGGLGSGGSIR.S sp|P35527|K1C9_HUMAN 1 1144.5585 55.25 78162 7811 2 1144.555599 573.2865 "Keratin, type I cytoskeletal 9 OS=Homo sapiens OX=9606 GN=KRT9 PE=1 SV=3" 9.75 1775.3 - 5.10E+06 - - - -2.5329 - 3.097 0.528 - 842.4 1 1 0 -0.0029 15 0 0 0 2.11E+09 3.81E+07 - - - 5.7191 0.9844 221125_WJC_METTL3_EV_vs_WT_F06.07833.07833.2 0.138 16-Nov R.EQEQLNVEK[136.11].R "sp|Q15643|TRIPB_HUMAN,tr|H0YJ97|H0YJ97_HUMAN" 2 1123.5601 1.29 78167 7833 2 1123.558029 562.7873 Thyroid receptor-interacting protein 11 OS=Homo sapiens OX=9606 GN=TRIP11 PE=1 SV=3 4.25 1778.5 - 3.74E+06 - - - -1.8148 - 1.593 0.049 - 252.2 1 2 0 -0.002 9 0 0 0 8.45E+08 6.53E+08 - - - 0.7493 0.9999 221125_WJC_METTL3_EV_vs_WT_F06.07834.07834.2 3.48E-05 16-Aug K.C[160.03]YSC[160.03]PVC[160.03]SR[166.11].V "sp|Q9P0T4|ZN581_HUMAN,tr|K7EM32|K7EM32_HUMAN" 2 1197.4605 0.001 78168 7834 2 1197.462016 599.7375 Zinc finger protein 581 OS=Homo sapiens OX=9606 GN=ZNF581 PE=1 SV=1 7.96 1778.6 - 1.27E+06 - - - 1.3036 - 1.573 0.691 - 196.9 1 2 0 0.0016 9 0 0 0 0.00E+00 7.48E+07 - - - 5.4547 0.9993 221125_WJC_METTL3_EV_vs_WT_F06.07835.07835.2 2.38E-06 20-Nov K.LC[160.03]VQNSPQEAR.N "sp|P33240|CSTF2_HUMAN,tr|A0A0A0MT56|A0A0A0MT56_HUMAN,tr|E9PID8|E9PID8_HUMAN,tr|E7EWR4|E7EWR4_HUMAN" 4 1300.6194 1.27 78169 7835 2 1300.615677 651.317 Cleavage stimulation factor subunit 2 OS=Homo sapiens OX=9606 GN=CSTF2 PE=1 SV=1 5.99 1778.8 - 1.37E+06 - - - -2.8502 - 2.435 0.396 - 555.7 1 2 0 -0.0037 11 0 0 0 1.09E+08 8.58E+07 - - - 4.3722 0.9998 221125_WJC_METTL3_EV_vs_WT_F06.07839.07839.2 0.0102 14-Aug R.DSC[160.03]PLDC[160.03]K.V "sp|P84103|SRSF3_HUMAN,tr|A0A087X2D0|A0A087X2D0_HUMAN" 2 993.3896 1.25 78171 7839 2 993.388462 497.7021 Serine\arginine-rich splicing factor 3 OS=Homo sapiens OX=9606 GN=SRSF3 PE=1 SV=1 4.21 1779.3 - 1.73E+06 - - - -1.1124 - 1.545 0.52 - 228.3 1 2 0 -0.0011 8 0 0 0 2.51E+08 2.01E+08 - - - 4.1934 0.9994 221125_WJC_METTL3_EV_vs_WT_F06.07865.07865.2 0.00515 18-Aug R.QDVDNASLAR.L "sp|P08670|VIME_HUMAN,tr|B0YJC5|B0YJC5_HUMAN,tr|B0YJC4|B0YJC4_HUMAN" 3 1087.5258 2.01 78182 7865 2 1087.523501 544.7702 Vimentin OS=Homo sapiens OX=9606 GN=VIM PE=1 SV=4 4.21 1782.7 - 7.30E+06 - - - -2.1149 - 1.755 0.42 - 144.9 1 2 0 -0.0023 10 0 0 0 3.37E+08 1.68E+08 - - - 3.7124 0.9999 221125_WJC_METTL3_EV_vs_WT_F06.07872.07872.2 5.13E-07 22-Nov K.VGGTSDVEVNEK[136.11].K "sp|P10809|CH60_HUMAN,tr|A0A7I2V2X6|A0A7I2V2X6_HUMAN,tr|A0A7I2YQK6|A0A7I2YQK6_HUMAN,tr|A0A7I2V599|A0A7I2V599_HUMAN" 4 1240.6027 1.31 78184 7872 2 1240.601271 621.3086 "60 kDa heat shock protein, mitochondrial OS=Homo sapiens OX=9606 GN=HSPD1 PE=1 SV=2" 4.14 1783.5 - 1.63E+06 - - - -1.1204 - 2.224 0.537 - 133.6 1 2 0 -0.0014 12 0 0 0 1.15E+08 8.74E+07 - - - 5.11 0.9941 221125_WJC_METTL3_EV_vs_WT_F06.07875.07875.2 0.099 20-Sep R.NPPPNSDPNLR.R sp|Q96I24|FUBP3_HUMAN 1 1219.5945 2.66 78185 7875 2 1219.590882 610.8046 Far upstream element-binding protein 3 OS=Homo sapiens OX=9606 GN=FUBP3 PE=1 SV=2 5.84 1783.9 - 1.46E+06 - - - -3.0067 - 1.494 0.272 - 288.5 1 2 0 -0.0037 11 0 0 0 7.24E+07 2.72E+07 - - - 2.1349 0.9789 221125_WJC_METTL3_EV_vs_WT_F06.07877.07877.2 0.00183 16-Sep R.QENQVPSVR[166.11].V "sp|P46020|KPB1_HUMAN,tr|A6NMN0|A6NMN0_HUMAN,tr|A6NIT2|A6NIT2_HUMAN" 3 1065.5442 2.82 78186 7877 2 1065.538181 533.7794 "Phosphorylase b kinase regulatory subunit alpha, skeletal muscle isoform OS=Homo sapiens OX=9606 GN=PHKA1 PE=1 SV=2" 6 1784.1 - 972764 - - - -5.6882 - 1.722 0.284 - 252.8 1 2 0 -0.0061 9 0 0 0 1.53E+08 5.43E+07 - - - 2.7091 0.9962 221125_WJC_METTL3_EV_vs_WT_F06.07881.07881.2 0.434 14-Sep K.RLEFENQK.T "sp|Q14683|SMC1A_HUMAN,tr|G8JLG1|G8JLG1_HUMAN,tr|A0A6Q8PHC3|A0A6Q8PHC3_HUMAN" 3 1062.5458 0.88 78188 7881 2 1062.547437 532.2802 Structural maintenance of chromosomes protein 1A OS=Homo sapiens OX=9606 GN=SMC1A PE=1 SV=2 6.14 1784.6 - 1.03E+06 - - - 1.5331 - 1.484 0.202 - 408.8 1 2 0 0.0016 8 0 0 0 8.21E+07 9.33E+07 - - - 1.723 0.9929 221125_WJC_METTL3_EV_vs_WT_F06.07882.07882.3 0.00284 Dec-40 K.GLVPEDDTK[136.11]EK[136.11].L "sp|Q15459|SF3A1_HUMAN,tr|H7C1L2|H7C1L2_HUMAN" 2 1245.6423 0.42 78189 7882 3 1245.638837 416.2214 Splicing factor 3A subunit 1 OS=Homo sapiens OX=9606 GN=SF3A1 PE=1 SV=1 4.32 1784.7 - 1.71E+06 - - - -2.8178 - 1.613 0.356 - 79.8 1 2 1 -0.0035 11 0 0 0 1.13E+08 2.71E+08 - - - 3.8663 0.9152 221125_WJC_METTL3_EV_vs_WT_F06.07887.07887.2 2.24 14-Aug K.SRLDQELK.L "sp|P46781|RS9_HUMAN,tr|C9JM19|C9JM19_HUMAN,tr|B5MCT8|B5MCT8_HUMAN,tr|F2Z3C0|F2Z3C0_HUMAN,tr|A8MXK4|A8MXK4_HUMAN" 5 987.5349 1.03 78191 7887 2 987.532805 494.7747 40S ribosomal protein S9 OS=Homo sapiens OX=9606 GN=RPS9 PE=1 SV=3 5.79 1785.3 - 1.25E+07 - - - -2.1306 - 1.706 0.097 - 376.3 1 2 1 -0.0021 8 0 0 0 7.35E+08 7.17E+08 - - - 1.3678 0.9999 221125_WJC_METTL3_EV_vs_WT_F06.07889.07889.3 1.86E-05 14/44 R.GGGQEER[166.11]PFVAR[166.11].F "sp|Q9HA64|KT3K_HUMAN,tr|I3L2G3|I3L2G3_HUMAN" 2 1321.6642 0.32 78193 7889 3 1321.662327 441.562 Ketosamine-3-kinase OS=Homo sapiens OX=9606 GN=FN3KRP PE=1 SV=2 6.14 1785.6 - 1.98E+06 - - - -1.4073 - 2.45 0.442 - 483.7 1 2 0 -0.0019 12 0 0 0 2.08E+07 6.51E+07 - - - 5.9512 0.9908 221125_WJC_METTL3_EV_vs_WT_F06.07892.07892.2 0.00585 18-Aug R.SDGFDEESQR.Y "sp|Q6ZUT1|NKAP1_HUMAN,tr|E9PKA8|E9PKA8_HUMAN,tr|E9PSC8|E9PSC8_HUMAN,tr|E9PQL5|E9PQL5_HUMAN" 4 1168.4633 2.83 78196 7892 2 1168.457515 585.2389 Uncharacterized protein NKAPD1 OS=Homo sapiens OX=9606 GN=NKAPD1 PE=1 SV=2 3.92 1786 - 1.44E+06 - - - -4.9167 - 1.105 0.498 - 121.4 1 2 0 -0.0057 10 0 0 0 3.37E+07 1.19E+07 - - - 2.9961 0.9563 221125_WJC_METTL3_EV_vs_WT_F06.07906.07906.3 1.4 Dec-40 K.LVSDSLSEHEK[136.11].N "sp|Q96KR1|ZFR_HUMAN,tr|H0Y8W1|H0Y8W1_HUMAN" 2 1250.6234 1.18 78203 7906 3 1250.620573 417.8817 Zinc finger RNA-binding protein OS=Homo sapiens OX=9606 GN=ZFR PE=1 SV=2 4.65 1787.8 - 3.91E+06 - - - -2.2573 - 1.687 0.121 - 170.8 1 2 0 -0.0028 11 0 0 0 1.38E+08 1.17E+08 - - - 1.3739 0.8502 221125_WJC_METTL3_EV_vs_WT_F06.07908.07908.3 0.369 Sep-40 K.LVSDSLSEHEK.N "sp|Q96KR1|ZFR_HUMAN,tr|H0Y8W1|H0Y8W1_HUMAN" 2 1242.6092 1.18 78205 7908 3 1242.608547 415.2103 Zinc finger RNA-binding protein OS=Homo sapiens OX=9606 GN=ZFR PE=1 SV=2 4.65 1787.9 - 4.77E+06 - - - -0.5223 - 1.346 0.102 - 33 5 2 0 -0.0006 11 0 0 0 1.38E+08 1.17E+08 - - - 0.1976 0.9996 221125_WJC_METTL3_EV_vs_WT_F06.07911.07911.3 1.69E-07 17/48 K.AMAPLHPHPAGMR[166.11].L "sp|Q9BY77|PDIP3_HUMAN,tr|F6VRR5|F6VRR5_HUMAN,tr|F8WCX5|F8WCX5_HUMAN" 3 1394.6939 1.5 78206 7911 3 1394.689354 465.9052 Polymerase delta-interacting protein 3 OS=Homo sapiens OX=9606 GN=POLDIP3 PE=1 SV=2 9.81 1788.3 - 4.62E+06 - - - -3.2595 - 2.85 0.364 - 423.1 1 2 0 -0.0045 13 0 0 0 3.72E+08 2.48E+08 - - - 5.4366 0.9913 221125_WJC_METTL3_EV_vs_WT_F06.07912.07912.2 0.937 14-Aug K.R[166.11]LEFENQK[136.11].T "sp|Q14683|SMC1A_HUMAN,tr|G8JLG1|G8JLG1_HUMAN,tr|A0A6Q8PHC3|A0A6Q8PHC3_HUMAN" 3 1080.5683 0.88 78207 7912 2 1080.566415 541.2914 Structural maintenance of chromosomes protein 1A OS=Homo sapiens OX=9606 GN=SMC1A PE=1 SV=2 6.14 1788.4 - 3.14E+06 - - - -1.7241 - 1.466 0.125 - 263.4 1 2 0 -0.0019 8 0 0 0 8.21E+07 9.33E+07 - - - 1.1174 0.9985 221125_WJC_METTL3_EV_vs_WT_F06.07919.07919.2 7.30E-05 13/20 K.LVSDSLSEHEK.N "sp|Q96KR1|ZFR_HUMAN,tr|H0Y8W1|H0Y8W1_HUMAN" 2 1242.6092 3 78211 7919 2 1242.605886 622.3119 Zinc finger RNA-binding protein OS=Homo sapiens OX=9606 GN=ZFR PE=1 SV=2 4.65 1789.3 - 2.00E+06 - - - -2.6637 - 2.139 0.282 - 458.3 1 2 0 -0.0033 11 0 0 0 7.27E+07 2.42E+07 - - - 3.1797 0.9995 221125_WJC_METTL3_EV_vs_WT_F06.07920.07920.2 0.0153 20-Dec K.LVSDSLSEHEK[136.11].N "sp|Q96KR1|ZFR_HUMAN,tr|H0Y8W1|H0Y8W1_HUMAN" 2 1250.6234 2.34 78212 7920 2 1250.621428 626.319 Zinc finger RNA-binding protein OS=Homo sapiens OX=9606 GN=ZFR PE=1 SV=2 4.65 1789.4 - 1.62E+06 - - - -1.5736 - 1.765 0.403 - 373.8 1 2 0 -0.002 11 0 0 0 5.66E+07 2.42E+07 - - - 3.5539 0.9935 221125_WJC_METTL3_EV_vs_WT_F06.07921.07921.2 0.000324 20-Nov K.EELEEEQRTEE.- "tr|K7EQX8|K7EQX8_HUMAN,tr|Q6ZR64|Q6ZR64_HUMAN" 2 1419.6001 1.37 78213 7921 2 1419.5965 710.8074 Matrix-remodeling-associated protein 7 OS=Homo sapiens OX=9606 GN=MXRA7 PE=1 SV=1 4 1789.5 - 489464 - - - -2.5697 - 2.04 0.441 - 476.6 1 2 1 -0.0036 11 0 0 0 1.27E+07 9.27E+06 - - - 4.2258 0.994 221125_WJC_METTL3_EV_vs_WT_F06.07923.07923.2 0.0493 12-Sep K.HQYYNLK.D sp|P13984|T2FB_HUMAN 1 964.4767 0.61 78214 7923 2 964.477912 483.2456 General transcription factor IIF subunit 2 OS=Homo sapiens OX=9606 GN=GTF2F2 PE=1 SV=2 8.5 1789.7 - 1.18E+06 - - - 1.2919 - 1.3 0.191 - 227.5 1 2 0 0.0012 7 0 0 0 1.04E+08 1.70E+08 - - - 1.2827 0.9964 221125_WJC_METTL3_EV_vs_WT_F06.07925.07925.2 0.0188 14-Aug K.HQAVQLPR.E sp|O95758|PTBP3_HUMAN 1 947.5301 0.96 78215 7925 2 947.52734 474.7723 Polypyrimidine tract-binding protein 3 OS=Homo sapiens OX=9606 GN=PTBP3 PE=1 SV=2 9.76 1790 - 997581 - - - -2.9107 - 1.444 0.318 - 159.7 1 2 0 -0.0028 8 0 0 0 6.50E+07 6.76E+07 - - - 2.497 1 221125_WJC_METTL3_EV_vs_WT_F06.07928.07928.2 1.34E-07 20-Oct K.AEEYTEETEER[166.11].E "sp|Q9Y2W1|TR150_HUMAN,tr|A0A3B3ITZ9|A0A3B3ITZ9_HUMAN" 2 1394.5713 3.33 78218 7928 2 1394.568669 698.2929 Thyroid hormone receptor-associated protein 3 OS=Homo sapiens OX=9606 GN=THRAP3 PE=1 SV=2 3.9 1790.3 - 468970 - - - -1.8895 - 2.298 0.671 - 432.1 1 2 0 -0.0026 11 0 0 0 1.02E+08 3.07E+07 - - - 6.247 0.9914 221125_WJC_METTL3_EV_vs_WT_F06.07929.07929.2 0.0182 20-Aug K.EELEEEQR[166.11]TEE.- "tr|K7EQX8|K7EQX8_HUMAN,tr|Q6ZR64|Q6ZR64_HUMAN" 2 1429.6084 1.37 78219 7929 2 1429.606601 715.8115 Matrix-remodeling-associated protein 7 OS=Homo sapiens OX=9606 GN=MXRA7 PE=1 SV=1 4 1790.4 - 361992 - - - -1.271 - 1.724 0.323 - 241.5 1 2 1 -0.0018 11 0 0 0 1.27E+07 9.27E+06 - - - 2.8995 1 221125_WJC_METTL3_EV_vs_WT_F06.07932.07932.2 1.28E-06 20-Nov K.AEEYTEETEER.E "sp|Q9Y2W1|TR150_HUMAN,tr|A0A3B3ITZ9|A0A3B3ITZ9_HUMAN" 2 1384.563 3.33 78220 7932 2 1384.562206 693.2888 Thyroid hormone receptor-associated protein 3 OS=Homo sapiens OX=9606 GN=THRAP3 PE=1 SV=2 3.9 1790.8 - 1.81E+06 - - - -0.598 - 2.572 0.662 - 568.8 1 2 0 -0.0008 11 0 0 0 1.02E+08 3.07E+07 - - - 6.4859 0.9999 221125_WJC_METTL3_EV_vs_WT_F06.07934.07934.2 8.36E-05 18-Dec K.STTTGHLIYK[136.11].C "sp|Q05639|EF1A2_HUMAN,sp|P68104|EF1A1_HUMAN,sp|Q5VTE0|EF1A3_HUMAN,tr|A0A2R8Y488|A0A2R8Y488_HUMAN,tr|A0A2R8YDN5|A0A2R8YDN5_HUMAN,tr|A0A7I2V659|A0A7I2V659_HUMAN,tr|A0A7I2V3H3|A0A7I2V3H3_HUMAN,tr|Q5JR01|Q5JR01_HUMAN,tr|A0A2U3TZH3|A0A2U3TZH3_HUMAN,tr|A0A7I2V5N4|A0A7I2V5N4_HUMAN,tr|A0A087WVQ9|A0A087WVQ9_HUMAN,tr|A6PW80|A6PW80_HUMAN,tr|A0A087WV01|A0A087WV01_HUMAN,tr|A0A2R8Y660|A0A2R8Y660_HUMAN,tr|A0A6Q8PFK6|A0A6Q8PFK6_HUMAN" 15 1127.6066 0.39 78222 7934 2 1127.606179 564.8106 Elongation factor 1-alpha 2 OS=Homo sapiens OX=9606 GN=EEF1A2 PE=1 SV=1 8.33 1790.9 - 3.89E+06 - - - -0.3946 - 2.525 0.482 - 762.4 1 2 0 -0.0004 10 0 0 0 1.16E+09 2.98E+09 - - - 5.1863 0.9325 221125_WJC_METTL3_EV_vs_WT_F06.07942.07942.3 0.000282 Oct-32 R.QREQEIALR.R "sp|Q6Y7W6|GGYF2_HUMAN,tr|A0A7I2V3H7|A0A7I2V3H7_HUMAN,tr|I1E4Y6|I1E4Y6_HUMAN,tr|A0A7I2V516|A0A7I2V516_HUMAN,tr|A0A7I2V3H0|A0A7I2V3H0_HUMAN,tr|A0A7I2V361|A0A7I2V361_HUMAN,tr|E7ESB6|E7ESB6_HUMAN" 7 1141.6204 1.82 78228 7942 3 1141.620788 381.5474 GRB10-interacting GYF protein 2 OS=Homo sapiens OX=9606 GN=GIGYF2 PE=1 SV=1 6.14 1791.9 - 3.78E+06 - - - 0.3661 - 2.186 0.058 - 135.3 1 2 1 0.0004 9 0 0 0 1.74E+08 9.55E+07 - - - 1.5435 0.999 221125_WJC_METTL3_EV_vs_WT_F06.07943.07943.2 0.0036 14-Aug R.LTWASHEK.M sp|P06702|S10A9_HUMAN 1 970.4872 1.4 78229 7943 2 970.486669 486.2509 Protein S100-A9 OS=Homo sapiens OX=9606 GN=S100A9 PE=1 SV=1 6.75 1792 - 4.00E+06 - - - -0.5791 - 1.587 0.263 - 251.7 1 2 0 -0.0006 8 0 0 0 2.19E+08 1.57E+08 - - - 2.3762 0.9995 221125_WJC_METTL3_EV_vs_WT_F06.07945.07945.2 2.77E-05 18-Sep K.NHEEEMNALR.G "sp|Q04695|K1C17_HUMAN,sp|P02533|K1C14_HUMAN,tr|K7EPJ9|K7EPJ9_HUMAN,tr|K7ESE1|K7ESE1_HUMAN,tr|F5GWP8|F5GWP8_HUMAN" 5 1241.5459 5102.9 78231 7945 2 1241.54486 621.7802 "Keratin, type I cytoskeletal 17 OS=Homo sapiens OX=9606 GN=KRT17 PE=1 SV=2" 4.75 1792.1 - 2.61E+06 - - - -0.8248 - 1.769 0.329 - 303.6 1 2 0 -0.001 10 0 0 0 2.19E+09 4.29E+05 - - - 3.0629 0.9186 221125_WJC_METTL3_EV_vs_WT_F06.07948.07948.2 0.00107 20-Oct M.APLHPHPAGMR[166.11].L "sp|Q9BY77|PDIP3_HUMAN,tr|F6VRR5|F6VRR5_HUMAN,tr|F8WCX5|F8WCX5_HUMAN" 3 1192.6163 0.9 78234 7948 2 1192.61993 597.3154 Polymerase delta-interacting protein 3 OS=Homo sapiens OX=9606 GN=POLDIP3 PE=1 SV=2 9.81 1792.4 - 387071 - - - 3.0429 - 1.917 0.37 - 295.2 1 1 0 0.0036 11 0 0 0 8.80E+06 9.81E+06 - - - 3.5331 0.9998 221125_WJC_METTL3_EV_vs_WT_F06.07951.07951.2 1.00E-05 18-Nov K.STTTGHLIYK.C "sp|Q05639|EF1A2_HUMAN,sp|P68104|EF1A1_HUMAN,sp|Q5VTE0|EF1A3_HUMAN,tr|A0A2R8Y488|A0A2R8Y488_HUMAN,tr|A0A2R8YDN5|A0A2R8YDN5_HUMAN,tr|A0A7I2V659|A0A7I2V659_HUMAN,tr|A0A7I2V3H3|A0A7I2V3H3_HUMAN,tr|Q5JR01|Q5JR01_HUMAN,tr|A0A2U3TZH3|A0A2U3TZH3_HUMAN,tr|A0A7I2V5N4|A0A7I2V5N4_HUMAN,tr|A0A087WVQ9|A0A087WVQ9_HUMAN,tr|A6PW80|A6PW80_HUMAN,tr|A0A087WV01|A0A087WV01_HUMAN,tr|A0A2R8Y660|A0A2R8Y660_HUMAN,tr|A0A6Q8PFK6|A0A6Q8PFK6_HUMAN" 15 1119.5924 0.39 78235 7951 2 1119.592058 560.8035 Elongation factor 1-alpha 2 OS=Homo sapiens OX=9606 GN=EEF1A2 PE=1 SV=1 8.33 1792.8 - 5.88E+06 - - - -0.3269 - 2.365 0.379 - 659.6 1 2 0 -0.0004 10 0 0 0 1.16E+09 2.98E+09 - - - 4.2429 0.9992 221125_WJC_METTL3_EV_vs_WT_F06.07952.07952.2 0.0224 16-Oct K.RPANQFVPR.L "sp|P67870|CSK2B_HUMAN,tr|Q5SRQ6|Q5SRQ6_HUMAN,tr|A0A7I2YQ78|A0A7I2YQ78_HUMAN" 3 1083.5938 1.12 78236 7952 2 1083.592886 542.8042 Casein kinase II subunit beta OS=Homo sapiens OX=9606 GN=CSNK2B PE=1 SV=1 12 1792.9 - 3.08E+06 - - - -0.8075 - 1.867 0.253 - 177.7 1 2 0 -0.0009 9 0 0 0 8.74E+07 7.83E+07 - - - 2.7156 0.9989 221125_WJC_METTL3_EV_vs_WT_F06.07953.07953.3 0.302 Sep-40 R.VALSEPQPERR.F "sp|Q9BXP5|SRRT_HUMAN,tr|H7C1K0|H7C1K0_HUMAN,tr|H7C3A1|H7C3A1_HUMAN" 3 1280.6837 1.1 78237 7953 3 1280.683822 427.9018 Serrate RNA effector molecule homolog OS=Homo sapiens OX=9606 GN=SRRT PE=1 SV=1 6.11 1792.9 - 2.81E+06 - - - 0.096 - 1.916 0.256 - 158.7 1 2 0 0.0001 11 0 0 0 5.51E+07 5.02E+07 - - - 3.2413 0.9996 221125_WJC_METTL3_EV_vs_WT_F06.07959.07959.2 0.000439 24-Oct K.LTTEATQTPVSNK.K sp|Q9BXS6|NUSAP_HUMAN 1 1388.7147 1.72 78243 7959 2 1388.715066 695.3646 Nucleolar and spindle-associated protein 1 OS=Homo sapiens OX=9606 GN=NUSAP1 PE=1 SV=1 6 1793.6 - 482590 - - - 0.2463 - 2.132 0.304 - 236.9 1 2 0 0.0003 13 0 0 0 7.28E+06 4.24E+06 - - - 3.2293 0.9998 221125_WJC_METTL3_EV_vs_WT_F06.07961.07961.2 0.0296 13/22 R.AIEAAPQEPEQK[136.11].R "sp|Q96CP2|FWCH2_HUMAN,tr|I3L1Y9|I3L1Y9_HUMAN" 2 1317.6656 0.11 78244 7961 2 1317.664123 659.8401 FLYWCH family member 2 OS=Homo sapiens OX=9606 GN=FLYWCH2 PE=1 SV=1 4.25 1793.8 - 892541 - - - -1.1171 - 2.469 0.407 - 574.8 1 2 0 -0.0015 12 0 0 0 1.89E+06 1.67E+07 - - - 4.4247 0.9999 221125_WJC_METTL3_EV_vs_WT_F06.07963.07963.3 0.000387 Aug-36 K.NHEEEMNALR.G "sp|Q04695|K1C17_HUMAN,sp|P02533|K1C14_HUMAN,tr|K7EPJ9|K7EPJ9_HUMAN,tr|K7ESE1|K7ESE1_HUMAN,tr|F5GWP8|F5GWP8_HUMAN" 5 1241.5459 2113.87 78245 7963 3 1241.545998 414.8559 "Keratin, type I cytoskeletal 17 OS=Homo sapiens OX=9606 GN=KRT17 PE=1 SV=2" 4.75 1794.1 - 2.20E+07 - - - 0.0918 - 1.737 0.494 - 161.3 1 2 0 0.0001 10 0 0 0 2.32E+09 1.10E+06 - - - 5.6601 0.9907 221125_WJC_METTL3_EV_vs_WT_F06.07964.07964.2 0.000101 14-Dec T.TTGHLIYK[136.11].C "sp|Q05639|EF1A2_HUMAN,sp|P68104|EF1A1_HUMAN,sp|Q5VTE0|EF1A3_HUMAN,tr|A0A2R8Y488|A0A2R8Y488_HUMAN,tr|A0A2R8YDN5|A0A2R8YDN5_HUMAN,tr|A0A7I2V659|A0A7I2V659_HUMAN,tr|A0A7I2V3H3|A0A7I2V3H3_HUMAN,tr|Q5JR01|Q5JR01_HUMAN,tr|A0A2U3TZH3|A0A2U3TZH3_HUMAN,tr|A0A7I2V5N4|A0A7I2V5N4_HUMAN,tr|A0A087WVQ9|A0A087WVQ9_HUMAN,tr|A6PW80|A6PW80_HUMAN,tr|A0A087WV01|A0A087WV01_HUMAN,tr|A0A2R8Y660|A0A2R8Y660_HUMAN,tr|A0A6Q8PFK6|A0A6Q8PFK6_HUMAN" 15 939.5269 0.52 78246 7964 2 939.526847 470.7707 Elongation factor 1-alpha 2 OS=Homo sapiens OX=9606 GN=EEF1A2 PE=1 SV=1 8.29 1794.1 - 7.63E+06 - - - -0.0745 - 2.335 0.383 - 783.6 1 1 0 -0.0001 8 0 0 0 2.64E+08 5.13E+08 - - - 4.4274 0.9999 221125_WJC_METTL3_EV_vs_WT_F06.07966.07966.2 3.19E-06 18-Dec R.QTEEQVNDLK.E sp|P12270|TPR_HUMAN 1 1202.5779 0.95 78248 7966 2 1202.577715 602.2962 Nucleoprotein TPR OS=Homo sapiens OX=9606 GN=TPR PE=1 SV=3 4.14 1794.2 - 3.59E+06 - - - -0.1505 - 2.383 0.414 - 717.1 1 2 0 -0.0002 10 0 0 0 7.53E+07 7.90E+07 - - - 4.5226 0.9957 221125_WJC_METTL3_EV_vs_WT_F06.07968.07968.2 0.0664 16-Dec R.QREQEIALR.R "sp|Q6Y7W6|GGYF2_HUMAN,tr|A0A7I2V3H7|A0A7I2V3H7_HUMAN,tr|I1E4Y6|I1E4Y6_HUMAN,tr|A0A7I2V516|A0A7I2V516_HUMAN,tr|A0A7I2V3H0|A0A7I2V3H0_HUMAN,tr|A0A7I2V361|A0A7I2V361_HUMAN,tr|E7ESB6|E7ESB6_HUMAN" 7 1141.6204 2.05 78250 7968 2 1141.622295 571.8175 GRB10-interacting GYF protein 2 OS=Homo sapiens OX=9606 GN=GIGYF2 PE=1 SV=1 6.14 1794.3 - 1.65E+06 - - - 1.6862 - 2.507 0.32 - 258.9 1 2 1 0.0019 9 0 0 0 3.05E+07 1.49E+07 - - - 4.0629 0.9658 221125_WJC_METTL3_EV_vs_WT_F06.07971.07971.3 0.00482 Sep-40 M.APLHPHPAGMR[166.11].L "sp|Q9BY77|PDIP3_HUMAN,tr|F6VRR5|F6VRR5_HUMAN,tr|F8WCX5|F8WCX5_HUMAN" 3 1192.6163 3.7 78253 7971 3 1192.615819 398.546 Polymerase delta-interacting protein 3 OS=Homo sapiens OX=9606 GN=POLDIP3 PE=1 SV=2 9.81 1794.6 - 1.27E+06 - - - -0.4042 - 1.931 0.334 - 74.5 1 1 0 -0.0005 11 0 0 0 8.70E+07 2.35E+07 - - - 4.133 0.9347 221125_WJC_METTL3_EV_vs_WT_F06.07975.07975.2 0.386 16-Aug K.IR[166.11]EYEQTLK[136.11].N "sp|Q13948|CASP_HUMAN,sp|P39880|CUX1_HUMAN,tr|A0A2R8Y8D0|A0A2R8Y8D0_HUMAN,tr|A0A2R8Y852|A0A2R8Y852_HUMAN,tr|A0A2R8YDI1|A0A2R8YDI1_HUMAN" 5 1196.652 1.3 78257 7975 2 1196.652431 599.3333 Protein CASP OS=Homo sapiens OX=9606 GN=CUX1 PE=1 SV=2 6.14 1795.1 - 157263 - - - 0.3535 - 1.576 0.085 - 227.1 1 2 1 0.0004 9 0 0 0 1.13E+07 8.66E+06 - - - 0.9847 0.9994 221125_WJC_METTL3_EV_vs_WT_F06.07977.07977.2 0.00475 16-Jun K.QDSGHLDLR[166.11].N "sp|Q86U44|MTA70_HUMAN,tr|B4E349|B4E349_HUMAN,tr|F5H6D8|F5H6D8_HUMAN,tr|B4DTN4|B4DTN4_HUMAN" 4 1049.5129 0.03 78258 7977 2 1049.513049 525.7637 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 5.21 1795.3 - 4.97E+07 - - - 0.1029 - 1.639 0.313 - 117.6 1 2 0 0.0001 9 0 0 0 3.85E+09 1.53E+11 - - - 2.7822 1 221125_WJC_METTL3_EV_vs_WT_F06.07979.07979.3 4.49E-06 14/48 K.AMAPLHPHPAGMR.L "sp|Q9BY77|PDIP3_HUMAN,tr|F6VRR5|F6VRR5_HUMAN,tr|F8WCX5|F8WCX5_HUMAN" 3 1384.6856 1.5 78260 7979 3 1384.685716 462.5692 Polymerase delta-interacting protein 3 OS=Homo sapiens OX=9606 GN=POLDIP3 PE=1 SV=2 9.81 1795.5 - 1.49E+07 - - - 0.0621 - 2.545 0.484 - 210.9 1 2 0 0.0001 13 0 0 0 3.72E+08 2.48E+08 - - - 6.4688 0.9993 221125_WJC_METTL3_EV_vs_WT_F06.07981.07981.2 0.196 16-Oct K.R[166.11]PANQFVPR[166.11].L "sp|P67870|CSK2B_HUMAN,tr|Q5SRQ6|Q5SRQ6_HUMAN,tr|A0A7I2YQ78|A0A7I2YQ78_HUMAN" 3 1103.6103 1.12 78262 7981 2 1103.610546 552.8124 Casein kinase II subunit beta OS=Homo sapiens OX=9606 GN=CSNK2B PE=1 SV=1 12 1795.6 - 4.39E+06 - - - 0.222 - 1.809 0.258 - 192.1 1 2 0 0.0002 9 0 0 0 8.74E+07 7.83E+07 - - - 2.6614 0.9991 221125_WJC_METTL3_EV_vs_WT_F06.07986.07986.2 8.84E-07 22-Dec R.ELTNQQEASVER.Q "sp|Q14203|DCTN1_HUMAN,tr|A0A804CDA6|A0A804CDA6_HUMAN,tr|E7EX90|E7EX90_HUMAN,tr|A0A7P0Z4C3|A0A7P0Z4C3_HUMAN,tr|Q6AWB1|Q6AWB1_HUMAN" 5 1402.6688 2.03 78266 7986 2 1402.674657 702.3417 Dynactin subunit 1 OS=Homo sapiens OX=9606 GN=DCTN1 PE=1 SV=3 4.25 1796.1 - 375785 - - - 4.1499 - 2.661 0.536 - 582.3 1 2 0 0.0058 12 0 0 0 6.28E+08 3.10E+08 - - - 5.5732 0.9263 221125_WJC_METTL3_EV_vs_WT_F06.07991.07991.2 0.554 12-Jul N.KIDSEGR.S "sp|O75762|TRPA1_HUMAN,tr|H0YAW0|H0YAW0_HUMAN" 2 803.4137 257.05 78269 7991 2 803.413268 402.7141 Transient receptor potential cation channel subfamily A member 1 OS=Homo sapiens OX=9606 GN=TRPA1 PE=1 SV=3 6.07 1796.6 - 9.92E+06 - - - -0.5763 - 1.466 0.259 - 240.1 1 1 0 -0.0005 7 0 0 0 2.50E+08 9.73E+05 - - - 2.1659 0.9999 221125_WJC_METTL3_EV_vs_WT_F06.07995.07995.2 1.90E-06 13/22 R.ELTNQQEASVER[166.11].Q "sp|Q14203|DCTN1_HUMAN,tr|A0A804CDA6|A0A804CDA6_HUMAN,tr|E7EX90|E7EX90_HUMAN,tr|A0A7P0Z4C3|A0A7P0Z4C3_HUMAN,tr|Q6AWB1|Q6AWB1_HUMAN" 5 1412.6771 2.03 78273 7995 2 1412.678593 707.3458 Dynactin subunit 1 OS=Homo sapiens OX=9606 GN=DCTN1 PE=1 SV=3 4.25 1797 - 1.15E+06 - - - 1.0526 - 2.595 0.562 - 760.4 1 2 0 0.0015 12 0 0 0 6.28E+08 3.10E+08 - - - 5.7005 0.9742 221125_WJC_METTL3_EV_vs_WT_F06.07999.07999.2 0.037 14-Aug T.TTGHLIYK.C "sp|Q05639|EF1A2_HUMAN,sp|P68104|EF1A1_HUMAN,sp|Q5VTE0|EF1A3_HUMAN,tr|A0A2R8Y488|A0A2R8Y488_HUMAN,tr|A0A2R8YDN5|A0A2R8YDN5_HUMAN,tr|A0A7I2V659|A0A7I2V659_HUMAN,tr|A0A7I2V3H3|A0A7I2V3H3_HUMAN,tr|Q5JR01|Q5JR01_HUMAN,tr|A0A2U3TZH3|A0A2U3TZH3_HUMAN,tr|A0A7I2V5N4|A0A7I2V5N4_HUMAN,tr|A0A087WVQ9|A0A087WVQ9_HUMAN,tr|A6PW80|A6PW80_HUMAN,tr|A0A087WV01|A0A087WV01_HUMAN,tr|A0A2R8Y660|A0A2R8Y660_HUMAN,tr|A0A6Q8PFK6|A0A6Q8PFK6_HUMAN" 15 931.5127 0.46 78275 7999 2 931.512902 466.7636 Elongation factor 1-alpha 2 OS=Homo sapiens OX=9606 GN=EEF1A2 PE=1 SV=1 8.29 1797.5 - 1.03E+07 - - - 0.1986 - 1.898 0.298 - 241 1 1 0 0.0002 8 0 0 0 2.37E+08 5.13E+08 - - - 3.1746 1 221125_WJC_METTL3_EV_vs_WT_F06.08000.08000.3 7.13E-06 Dec-40 R.HQGVMVGMGQK.D "sp|P63261|ACTG_HUMAN,sp|P68133|ACTS_HUMAN,sp|P62736|ACTA_HUMAN,sp|P68032|ACTC_HUMAN,sp|Q562R1|ACTBL_HUMAN,sp|P60709|ACTB_HUMAN,sp|P63267|ACTH_HUMAN,tr|I3L3I0|I3L3I0_HUMAN,tr|G5E9R0|G5E9R0_HUMAN,tr|E7EVS6|E7EVS6_HUMAN,tr|B8ZZJ2|B8ZZJ2_HUMAN,tr|J3KT65|J3KT65_HUMAN,tr|I3L3R2|I3L3R2_HUMAN,tr|K7EM38|K7EM38_HUMAN,tr|F6QUT6|F6QUT6_HUMAN,tr|C9JTX5|C9JTX5_HUMAN,tr|A0A6Q8PH58|A0A6Q8PH58_HUMAN,tr|F6UVQ4|F6UVQ4_HUMAN,tr|F8WB63|F8WB63_HUMAN,tr|I3L1U9|I3L1U9_HUMAN,tr|A0A2R8Y793|A0A2R8Y793_HUMAN,tr|I3L4N8|I3L4N8_HUMAN,tr|C9JUM1|C9JUM1_HUMAN,tr|C9JZR7|C9JZR7_HUMAN,tr|C9JFL5|C9JFL5_HUMAN,tr|A0A2R8YGF8|A0A2R8YGF8_HUMAN,tr|A6NL76|A6NL76_HUMAN" 27 1170.5638 0.86 78276 8000 3 1170.561471 391.1952 "Actin, cytoplasmic 2 OS=Homo sapiens OX=9606 GN=ACTG1 PE=1 SV=1" 8.76 1797.6 - 9.19E+06 - - - -1.9751 - 2.278 0.523 - 229.7 1 2 0 -0.0023 11 0 0 0 6.06E+08 7.03E+08 - - - 6.7091 0.9992 221125_WJC_METTL3_EV_vs_WT_F06.08001.08001.2 0.000389 16-Oct K.KNQELEVVR.Q "sp|Q14203|DCTN1_HUMAN,tr|A0A804CDA6|A0A804CDA6_HUMAN,tr|E7EX90|E7EX90_HUMAN,tr|A0A7P0Z4C3|A0A7P0Z4C3_HUMAN,tr|Q6AWB1|Q6AWB1_HUMAN" 5 1113.6142 3.62 78277 8001 2 1113.617201 557.8144 Dynactin subunit 1 OS=Homo sapiens OX=9606 GN=DCTN1 PE=1 SV=3 6.14 1797.6 - 4.36E+06 - - - 2.6751 - 2.102 0.376 - 419.5 1 2 0 0.003 9 0 0 0 8.90E+07 2.46E+07 - - - 3.9664 0.997 221125_WJC_METTL3_EV_vs_WT_F06.08002.08002.2 0.154 16-Aug R.R[166.11]FDGVQDPR[166.11].L sp|O00264|PGRC1_HUMAN 1 1108.5528 1.65 78278 8002 2 1108.553575 555.2837 Membrane-associated progesterone receptor component 1 OS=Homo sapiens OX=9606 GN=PGRMC1 PE=1 SV=3 5.96 1797.7 - 3.10E+06 - - - 0.6576 - 1.423 0.206 - 177 1 2 0 0.0007 9 0 0 0 2.66E+08 1.61E+08 - - - 1.5829 0.9999 221125_WJC_METTL3_EV_vs_WT_F06.08007.08007.2 9.77E-06 20-Dec R.IPSTDTQVQPK.L "sp|Q9ULV3|CIZ1_HUMAN,tr|Q5SYW2|Q5SYW2_HUMAN,tr|F5H2X7|F5H2X7_HUMAN,tr|H0Y5D5|H0Y5D5_HUMAN,tr|A0A494C0L7|A0A494C0L7_HUMAN,tr|Q9BTG3|Q9BTG3_HUMAN" 6 1212.635 4.08 78283 8007 2 1212.636006 607.3248 Cip1-interacting zinc finger protein OS=Homo sapiens OX=9606 GN=CIZ1 PE=1 SV=2 5.84 1798.2 - 1.25E+06 - - - 0.8156 - 2.085 0.532 - 515 1 2 0 0.001 11 0 0 0 6.40E+07 1.57E+07 - - - 4.9578 1 221125_WJC_METTL3_EV_vs_WT_F06.08011.08011.3 1.54E-05 Oct-40 R.HQGVMVGMGQK[136.11].D "sp|P63261|ACTG_HUMAN,sp|P68133|ACTS_HUMAN,sp|P62736|ACTA_HUMAN,sp|P68032|ACTC_HUMAN,sp|Q562R1|ACTBL_HUMAN,sp|P60709|ACTB_HUMAN,sp|P63267|ACTH_HUMAN,tr|I3L3I0|I3L3I0_HUMAN,tr|G5E9R0|G5E9R0_HUMAN,tr|E7EVS6|E7EVS6_HUMAN,tr|B8ZZJ2|B8ZZJ2_HUMAN,tr|J3KT65|J3KT65_HUMAN,tr|I3L3R2|I3L3R2_HUMAN,tr|K7EM38|K7EM38_HUMAN,tr|F6QUT6|F6QUT6_HUMAN,tr|C9JTX5|C9JTX5_HUMAN,tr|A0A6Q8PH58|A0A6Q8PH58_HUMAN,tr|F6UVQ4|F6UVQ4_HUMAN,tr|F8WB63|F8WB63_HUMAN,tr|I3L1U9|I3L1U9_HUMAN,tr|A0A2R8Y793|A0A2R8Y793_HUMAN,tr|I3L4N8|I3L4N8_HUMAN,tr|C9JUM1|C9JUM1_HUMAN,tr|C9JZR7|C9JZR7_HUMAN,tr|C9JFL5|C9JFL5_HUMAN,tr|A0A2R8YGF8|A0A2R8YGF8_HUMAN,tr|A6NL76|A6NL76_HUMAN" 27 1178.578 0.86 78285 8011 3 1178.576618 393.8666 "Actin, cytoplasmic 2 OS=Homo sapiens OX=9606 GN=ACTG1 PE=1 SV=1" 8.76 1798.7 - 1.87E+07 - - - -1.1582 - 2.273 0.471 - 245.7 1 2 0 -0.0014 11 0 0 0 6.06E+08 7.02E+08 - - - 6.1234 1 221125_WJC_METTL3_EV_vs_WT_F06.08012.08012.2 2.65E-09 13/20 R.HQGVMVGMGQK[136.11].D "sp|P63261|ACTG_HUMAN,sp|P68133|ACTS_HUMAN,sp|P62736|ACTA_HUMAN,sp|P68032|ACTC_HUMAN,sp|Q562R1|ACTBL_HUMAN,sp|P60709|ACTB_HUMAN,sp|P63267|ACTH_HUMAN,tr|I3L3I0|I3L3I0_HUMAN,tr|G5E9R0|G5E9R0_HUMAN,tr|E7EVS6|E7EVS6_HUMAN,tr|B8ZZJ2|B8ZZJ2_HUMAN,tr|J3KT65|J3KT65_HUMAN,tr|I3L3R2|I3L3R2_HUMAN,tr|K7EM38|K7EM38_HUMAN,tr|F6QUT6|F6QUT6_HUMAN,tr|C9JTX5|C9JTX5_HUMAN,tr|A0A6Q8PH58|A0A6Q8PH58_HUMAN,tr|F6UVQ4|F6UVQ4_HUMAN,tr|F8WB63|F8WB63_HUMAN,tr|I3L1U9|I3L1U9_HUMAN,tr|A0A2R8Y793|A0A2R8Y793_HUMAN,tr|I3L4N8|I3L4N8_HUMAN,tr|C9JUM1|C9JUM1_HUMAN,tr|C9JZR7|C9JZR7_HUMAN,tr|C9JFL5|C9JFL5_HUMAN,tr|A0A2R8YGF8|A0A2R8YGF8_HUMAN,tr|A6NL76|A6NL76_HUMAN" 27 1178.578 0.76 78286 8012 2 1178.578133 590.2963 "Actin, cytoplasmic 2 OS=Homo sapiens OX=9606 GN=ACTG1 PE=1 SV=1" 8.76 1798.7 - 9.18E+06 - - - 0.1273 - 3.036 0.651 - 411.3 1 2 0 0.0001 11 0 0 0 2.79E+08 3.69E+08 - - - 6.8535 0.9661 221125_WJC_METTL3_EV_vs_WT_F06.08014.08014.2 0.00427 16-Nov S.TTTGHLIYK.C "sp|Q05639|EF1A2_HUMAN,sp|P68104|EF1A1_HUMAN,sp|Q5VTE0|EF1A3_HUMAN,tr|A0A2R8Y488|A0A2R8Y488_HUMAN,tr|A0A2R8YDN5|A0A2R8YDN5_HUMAN,tr|A0A7I2V659|A0A7I2V659_HUMAN,tr|A0A7I2V3H3|A0A7I2V3H3_HUMAN,tr|Q5JR01|Q5JR01_HUMAN,tr|A0A2U3TZH3|A0A2U3TZH3_HUMAN,tr|A0A7I2V5N4|A0A7I2V5N4_HUMAN,tr|A0A087WVQ9|A0A087WVQ9_HUMAN,tr|A6PW80|A6PW80_HUMAN,tr|A0A087WV01|A0A087WV01_HUMAN,tr|A0A2R8Y660|A0A2R8Y660_HUMAN,tr|A0A6Q8PFK6|A0A6Q8PFK6_HUMAN" 15 1032.5604 0.48 78288 8014 2 1032.559781 517.2875 Elongation factor 1-alpha 2 OS=Homo sapiens OX=9606 GN=EEF1A2 PE=1 SV=1 8.29 1798.8 - 4.37E+06 - - - -0.5946 - 1.707 0.315 - 334.9 1 1 0 -0.0006 9 0 0 0 8.31E+07 1.71E+08 - - - 2.9144 0.9861 221125_WJC_METTL3_EV_vs_WT_F06.08015.08015.3 0.0343 Nov-40 R.SFSSQRPVVDR.Q "sp|Q5JSZ5|PRC2B_HUMAN,tr|A0A804HKC3|A0A804HKC3_HUMAN,tr|A0A804HJR4|A0A804HJR4_HUMAN" 3 1276.6524 1.41 78289 8015 3 1276.651439 426.5581 Protein PRRC2B OS=Homo sapiens OX=9606 GN=PRRC2B PE=1 SV=2 9.31 1798.9 - 2.33E+06 - - - -0.7512 - 1.256 0.217 - 153.6 1 2 0 -0.001 11 0 0 0 1.47E+08 1.04E+08 - - - 1.6066 1 221125_WJC_METTL3_EV_vs_WT_F06.08019.08019.2 4.40E-07 14/22 K.VGGTSDVEVNEK.K "sp|P10809|CH60_HUMAN,tr|A0A7I2V2X6|A0A7I2V2X6_HUMAN,tr|A0A7I2YQK6|A0A7I2YQK6_HUMAN,tr|A0A7I2V599|A0A7I2V599_HUMAN" 4 1232.5885 2.03 78292 8019 2 1232.587969 617.3015 "60 kDa heat shock protein, mitochondrial OS=Homo sapiens OX=9606 GN=HSPD1 PE=1 SV=2" 4.14 1799.3 - 1.54E+06 - - - -0.3992 - 2.89 0.614 - 894.6 1 2 0 -0.0005 12 0 0 0 6.14E+07 3.03E+07 - - - 6.3682 0.9997 221125_WJC_METTL3_EV_vs_WT_F06.08025.08025.2 0.000324 22-Dec K.GSAGAPSVENVK.N "sp|P35813|PPM1A_HUMAN,tr|E9PL75|E9PL75_HUMAN,tr|E9PKB5|E9PKB5_HUMAN,tr|E9PJN3|E9PJN3_HUMAN" 4 1114.5619 2.2 78295 8025 2 1114.562046 558.2882 Protein phosphatase 1A OS=Homo sapiens OX=9606 GN=PPM1A PE=1 SV=1 6 1800 - 4.50E+06 - - - 0.1741 - 1.789 0.395 - 346.5 1 2 0 0.0002 12 0 0 0 1.38E+08 6.26E+07 - - - 3.4888 0.9998 221125_WJC_METTL3_EV_vs_WT_F06.08026.08026.2 8.51E-05 16-Dec K.KYAMEQSIK.S "sp|Q9UHX1|PUF60_HUMAN,tr|A0A0J9YYL3|A0A0J9YYL3_HUMAN,tr|A0A0J9YWM1|A0A0J9YWM1_HUMAN,tr|H0YEM1|H0YEM1_HUMAN,tr|E9PMU7|E9PMU7_HUMAN,tr|E9PN18|E9PN18_HUMAN,tr|E9PL19|E9PL19_HUMAN,tr|A0A0J9YVR6|A0A0J9YVR6_HUMAN,tr|A0A0J9YXX5|A0A0J9YXX5_HUMAN,tr|A0A0J9YXJ8|A0A0J9YXJ8_HUMAN,tr|E9PQ56|E9PQ56_HUMAN,tr|A0A0J9YVP6|A0A0J9YVP6_HUMAN" 12 1096.5587 0.32 78296 8026 2 1096.55957 549.2866 Poly(U)-binding-splicing factor PUF60 OS=Homo sapiens OX=9606 GN=PUF60 PE=1 SV=1 8.5 1800.1 - 841190 - - - 0.8107 - 2.015 0.455 - 435.5 1 2 0 0.0009 9 0 0 0 1.67E+07 5.15E+07 - - - 4.4283 0.9998 221125_WJC_METTL3_EV_vs_WT_F06.08027.08027.2 0.00118 20-Dec R.HQGVMVGMGQK.D "sp|P63261|ACTG_HUMAN,sp|P68133|ACTS_HUMAN,sp|P62736|ACTA_HUMAN,sp|P68032|ACTC_HUMAN,sp|Q562R1|ACTBL_HUMAN,sp|P60709|ACTB_HUMAN,sp|P63267|ACTH_HUMAN,tr|I3L3I0|I3L3I0_HUMAN,tr|G5E9R0|G5E9R0_HUMAN,tr|E7EVS6|E7EVS6_HUMAN,tr|B8ZZJ2|B8ZZJ2_HUMAN,tr|J3KT65|J3KT65_HUMAN,tr|I3L3R2|I3L3R2_HUMAN,tr|K7EM38|K7EM38_HUMAN,tr|F6QUT6|F6QUT6_HUMAN,tr|C9JTX5|C9JTX5_HUMAN,tr|A0A6Q8PH58|A0A6Q8PH58_HUMAN,tr|F6UVQ4|F6UVQ4_HUMAN,tr|F8WB63|F8WB63_HUMAN,tr|I3L1U9|I3L1U9_HUMAN,tr|A0A2R8Y793|A0A2R8Y793_HUMAN,tr|I3L4N8|I3L4N8_HUMAN,tr|C9JUM1|C9JUM1_HUMAN,tr|C9JZR7|C9JZR7_HUMAN,tr|C9JFL5|C9JFL5_HUMAN,tr|A0A2R8YGF8|A0A2R8YGF8_HUMAN,tr|A6NL76|A6NL76_HUMAN" 27 1170.5638 0.76 78297 8027 2 1170.564531 586.2892 "Actin, cytoplasmic 2 OS=Homo sapiens OX=9606 GN=ACTG1 PE=1 SV=1" 8.76 1800.1 - 8.30E+06 - - - 0.639 - 2.247 0.463 - 321.8 1 2 0 0.0007 11 0 0 0 2.79E+08 3.69E+08 - - - 4.6506 0.8956 221125_WJC_METTL3_EV_vs_WT_F06.08029.08029.2 0.158 12-Aug R.TKIDWNK.L "sp|P52907|CAZA1_HUMAN,sp|P47755|CAZA2_HUMAN" 2 903.4814 0.77 78299 8029 2 903.480062 452.748 F-actin-capping protein subunit alpha-1 OS=Homo sapiens OX=9606 GN=CAPZA1 PE=1 SV=3 8.26 1800.3 - 1.74E+06 - - - -1.4998 - 1.347 0.124 - 203.9 1 2 1 -0.0014 7 0 0 0 4.21E+07 5.43E+07 - - - 0.9003 0.9913 221125_WJC_METTL3_EV_vs_WT_F06.08030.08030.2 0.526 18-Sep K.LKELQNEVEK.Q "sp|Q86U42|PABP2_HUMAN,tr|B4DEH8|B4DEH8_HUMAN,tr|G3V4T2|G3V4T2_HUMAN,tr|A0A7I2V383|A0A7I2V383_HUMAN" 4 1228.6663 0.87 78300 8030 2 1228.666877 615.3404 Polyadenylate-binding protein 2 OS=Homo sapiens OX=9606 GN=PABPN1 PE=1 SV=3 4.79 1800.4 - 1.56E+06 - - - 0.4558 - 1.788 0.271 - 168.3 1 2 1 0.0006 10 0 0 0 4.65E+07 5.34E+07 - - - 2.6645 0.9998 221125_WJC_METTL3_EV_vs_WT_F06.08032.08032.2 0.00077 24-Dec K.DDVAPESGDTTVK[136.11].K "sp|O76021|RL1D1_HUMAN,tr|J3QSV6|J3QSV6_HUMAN" 2 1340.6187 1.07 78301 8032 2 1340.617553 671.3166 Ribosomal L1 domain-containing protein 1 OS=Homo sapiens OX=9606 GN=RSL1D1 PE=1 SV=3 3.84 1800.7 - 856266 - - - -0.8593 - 2.003 0.473 - 490.1 1 2 0 -0.0012 13 0 0 0 1.95E+07 1.82E+07 - - - 4.317 1 221125_WJC_METTL3_EV_vs_WT_F06.08034.08034.3 9.23E-06 Oct-48 K.LMELHGEGSSSGK[136.11].A "sp|P61247|RS3A_HUMAN,tr|D6R9B6|D6R9B6_HUMAN,tr|H0Y9Y4|H0Y9Y4_HUMAN,tr|D6RAT0|D6RAT0_HUMAN,tr|D6RG13|D6RG13_HUMAN" 5 1338.6329 0.89 78302 8034 3 1338.632206 447.2182 40S ribosomal protein S3a OS=Homo sapiens OX=9606 GN=RPS3A PE=1 SV=2 5.4 1800.9 - 2.61E+06 - - - -0.5296 - 2.4 0.485 - 109.7 1 2 0 -0.0007 13 0 0 0 4.38E+08 4.90E+08 - - - 6.3207 0.9841 221125_WJC_METTL3_EV_vs_WT_F06.08035.08035.2 0.00459 16-Nov K.TKEIEQVYR.Q "sp|Q8NEY8|PPHLN_HUMAN,tr|B7Z8L1|B7Z8L1_HUMAN,tr|F8W6A0|F8W6A0_HUMAN,tr|F8W0Q9|F8W0Q9_HUMAN,tr|F8WF16|F8WF16_HUMAN" 5 1164.6139 1.29 78303 8035 2 1164.6104 583.3142 Periphilin-1 OS=Homo sapiens OX=9606 GN=PPHLN1 PE=1 SV=2 5.81 1801 - 1.13E+06 - - - -2.995 - 2.116 0.309 - 430.8 1 2 1 -0.0035 9 0 0 0 3.79E+07 2.93E+07 - - - 3.4906 1 221125_WJC_METTL3_EV_vs_WT_F06.08036.08036.3 1.86E-05 15/48 K.LMELHGEGSSSGK.A "sp|P61247|RS3A_HUMAN,tr|D6R9B6|D6R9B6_HUMAN,tr|H0Y9Y4|H0Y9Y4_HUMAN,tr|D6RAT0|D6RAT0_HUMAN,tr|D6RG13|D6RG13_HUMAN" 5 1330.6187 0.89 78304 8036 3 1330.616932 444.5468 40S ribosomal protein S3a OS=Homo sapiens OX=9606 GN=RPS3A PE=1 SV=2 5.4 1801.1 - 2.57E+06 - - - -1.34 - 2.711 0.543 - 356.3 1 2 0 -0.0018 13 0 0 0 4.38E+08 4.90E+08 - - - 7.2974 0.9998 221125_WJC_METTL3_EV_vs_WT_F06.08041.08041.2 0.000207 16-Aug K.DYGNSPLHR[166.11].F "sp|P26599|PTBP1_HUMAN,tr|A0A0U1RRM4|A0A0U1RRM4_HUMAN,tr|A6NLN1|A6NLN1_HUMAN,tr|K7ELW5|K7ELW5_HUMAN,tr|A0A0D9SF20|A0A0D9SF20_HUMAN,tr|A0A7I2V621|A0A7I2V621_HUMAN,tr|A0A087WUW5|A0A087WUW5_HUMAN" 7 1067.5024 0.88 78307 8041 2 1067.503468 534.7585 Polypyrimidine tract-binding protein 1 OS=Homo sapiens OX=9606 GN=PTBP1 PE=1 SV=1 6.74 1801.7 - 6.27E+06 - - - 1.022 - 1.838 0.497 - 256.2 1 2 0 0.0011 9 0 0 0 3.10E+08 3.53E+08 - - - 4.4724 0.9998 221125_WJC_METTL3_EV_vs_WT_F06.08043.08043.2 0.025 16-Sep K.DYGNSPLHR.F "sp|P26599|PTBP1_HUMAN,tr|A0A0U1RRM4|A0A0U1RRM4_HUMAN,tr|A6NLN1|A6NLN1_HUMAN,tr|K7ELW5|K7ELW5_HUMAN,tr|A0A0D9SF20|A0A0D9SF20_HUMAN,tr|A0A7I2V621|A0A7I2V621_HUMAN,tr|A0A087WUW5|A0A087WUW5_HUMAN" 7 1057.4941 0.87 78309 8043 2 1057.494005 529.7543 Polypyrimidine tract-binding protein 1 OS=Homo sapiens OX=9606 GN=PTBP1 PE=1 SV=1 6.74 1801.8 - 4.87E+06 - - - -0.0965 - 1.884 0.438 - 311.2 1 2 0 -0.0001 9 0 0 0 3.06E+08 3.53E+08 - - - 4.1085 0.8405 221125_WJC_METTL3_EV_vs_WT_F06.08045.08045.2 2.42 18-May R.LAEC[160.03]C[160.03]IAANK.G "sp|Q9H9A5|CNO10_HUMAN,tr|E9PCN5|E9PCN5_HUMAN" 2 1148.5318 0.47 78311 8045 2 1148.528634 575.2732 CCR4-NOT transcription complex subunit 10 OS=Homo sapiens OX=9606 GN=CNOT10 PE=1 SV=1 5.99 1802 - 1.10E+06 - - - -2.7696 - 1.132 0.079 - 34.9 7 2 0 -0.0032 10 0 0 0 2.95E+07 6.22E+07 - - - -0.4079 1 221125_WJC_METTL3_EV_vs_WT_F06.08049.08049.2 1.42E-06 24-Dec K.LMELHGEGSSSGK.A "sp|P61247|RS3A_HUMAN,tr|D6R9B6|D6R9B6_HUMAN,tr|H0Y9Y4|H0Y9Y4_HUMAN,tr|D6RAT0|D6RAT0_HUMAN,tr|D6RG13|D6RG13_HUMAN" 5 1330.6187 0.87 78313 8049 2 1330.611916 666.3166 40S ribosomal protein S3a OS=Homo sapiens OX=9606 GN=RPS3A PE=1 SV=2 5.4 1802.5 - 576984 - - - -5.1097 - 2.328 0.639 - 570.2 1 2 0 -0.0068 13 0 0 0 4.31E+07 4.93E+07 - - - 5.9273 0.9995 221125_WJC_METTL3_EV_vs_WT_F06.08050.08050.2 5.26E-06 16/24 K.LMELHGEGSSSGK[136.11].A "sp|P61247|RS3A_HUMAN,tr|D6R9B6|D6R9B6_HUMAN,tr|H0Y9Y4|H0Y9Y4_HUMAN,tr|D6RAT0|D6RAT0_HUMAN,tr|D6RG13|D6RG13_HUMAN" 5 1338.6329 0.87 78314 8050 2 1338.628827 670.3237 40S ribosomal protein S3a OS=Homo sapiens OX=9606 GN=RPS3A PE=1 SV=2 5.4 1802.6 - 741453 - - - -3.0539 - 2.8 0.474 - 1064 1 2 0 -0.0041 13 0 0 0 4.31E+07 4.93E+07 - - - 5.1832 0.9932 221125_WJC_METTL3_EV_vs_WT_F06.08054.08054.2 0.000474 18-Aug K.SVFSQSGNSR[166.11].E "sp|P30260|CDC27_HUMAN,tr|G5EA36|G5EA36_HUMAN" 2 1077.5079 17.18 78316 8054 2 1077.504866 539.7612 Cell division cycle protein 27 homolog OS=Homo sapiens OX=9606 GN=CDC27 PE=1 SV=2 9.47 1803.1 - 1.06E+06 - - - -2.7749 - 1.54 0.221 - 244.7 1 2 0 -0.003 10 0 0 0 5.39E+08 3.14E+07 - - - 1.8776 0.9999 221125_WJC_METTL3_EV_vs_WT_F06.08057.08057.2 0.0172 18-Jul R.C[160.03]C[160.03]SFDGDADR.L "sp|O95394|AGM1_HUMAN,tr|A0A494C1E2|A0A494C1E2_HUMAN,tr|J3KN95|J3KN95_HUMAN,tr|A0A494C0G1|A0A494C0G1_HUMAN,tr|A0A494C1Q4|A0A494C1Q4_HUMAN,tr|H0Y987|H0Y987_HUMAN,tr|A0A087WT27|A0A087WT27_HUMAN" 7 1201.4128 1.06 78318 8057 2 1201.412621 601.7137 Phosphoacetylglucosamine mutase OS=Homo sapiens OX=9606 GN=PGM3 PE=1 SV=1 3.93 1803.5 - 155068 - - - -0.1673 - 1.49 0.65 - 133.1 1 2 0 -0.0002 10 0 0 0 5.00E+06 4.72E+06 - - - 4.9549 0.9995 221125_WJC_METTL3_EV_vs_WT_F06.08064.08064.2 0.000681 18-Sep K.AHLTNQYMQR[166.11].V "sp|Q13310|PABP4_HUMAN,sp|P11940|PABP1_HUMAN,tr|A0A7I2V5W9|A0A7I2V5W9_HUMAN,tr|H0YEU6|H0YEU6_HUMAN,tr|A0A7I2YQE4|A0A7I2YQE4_HUMAN,tr|A0A7I2V649|A0A7I2V649_HUMAN,tr|B1ANR0|B1ANR0_HUMAN,tr|A0A7I2V4L7|A0A7I2V4L7_HUMAN,tr|H0YB86|H0YB86_HUMAN,tr|H0YAR2|H0YAR2_HUMAN,tr|E7ERJ7|E7ERJ7_HUMAN,tr|A0A7I2V598|A0A7I2V598_HUMAN,tr|A0A7I2YQ88|A0A7I2YQ88_HUMAN,tr|A0A7I2V4V6|A0A7I2V4V6_HUMAN,tr|H0Y5F5|H0Y5F5_HUMAN,tr|A0A087WTT1|A0A087WTT1_HUMAN,tr|A0A7I2YQ90|A0A7I2YQ90_HUMAN,tr|A0A7I2V4N4|A0A7I2V4N4_HUMAN,tr|E7EQV3|E7EQV3_HUMAN" 19 1270.6116 1.46 78321 8064 2 1270.613403 636.3131 Polyadenylate-binding protein 4 OS=Homo sapiens OX=9606 GN=PABPC4 PE=1 SV=1 8.8 1804.5 - 258866 - - - 1.4111 - 1.899 0.383 - 286.2 1 2 0 0.0018 10 0 0 0 1.24E+07 8.50E+06 - - - 3.6594 1 221125_WJC_METTL3_EV_vs_WT_F06.08067.08067.3 5.64E-06 14/44 R.AAPGAEFAPNKR.R "sp|Q15233|NONO_HUMAN,tr|A0A7I2V535|A0A7I2V535_HUMAN,tr|A0A7I2V4K9|A0A7I2V4K9_HUMAN,tr|A0A7I2V4J2|A0A7I2V4J2_HUMAN,tr|A0A7I2V5Y7|A0A7I2V5Y7_HUMAN" 5 1227.636 2.88 78322 8067 3 1227.636542 410.2193 Non-POU domain-containing octamer-binding protein OS=Homo sapiens OX=9606 GN=NONO PE=1 SV=4 8.79 1804.9 - 5.25E+06 - - - 0.4252 - 2.247 0.46 - 332.5 1 2 0 0.0005 12 0 0 0 1.04E+09 3.60E+08 - - - 5.9125 0.9995 221125_WJC_METTL3_EV_vs_WT_F06.08068.08068.2 4.94E-05 18-Oct K.AHLTNQYMQR.V "sp|Q13310|PABP4_HUMAN,sp|P11940|PABP1_HUMAN,tr|A0A7I2V5W9|A0A7I2V5W9_HUMAN,tr|H0YEU6|H0YEU6_HUMAN,tr|A0A7I2YQE4|A0A7I2YQE4_HUMAN,tr|A0A7I2V649|A0A7I2V649_HUMAN,tr|B1ANR0|B1ANR0_HUMAN,tr|A0A7I2V4L7|A0A7I2V4L7_HUMAN,tr|H0YB86|H0YB86_HUMAN,tr|H0YAR2|H0YAR2_HUMAN,tr|E7ERJ7|E7ERJ7_HUMAN,tr|A0A7I2V598|A0A7I2V598_HUMAN,tr|A0A7I2YQ88|A0A7I2YQ88_HUMAN,tr|A0A7I2V4V6|A0A7I2V4V6_HUMAN,tr|H0Y5F5|H0Y5F5_HUMAN,tr|A0A087WTT1|A0A087WTT1_HUMAN,tr|A0A7I2YQ90|A0A7I2YQ90_HUMAN,tr|A0A7I2V4N4|A0A7I2V4N4_HUMAN,tr|E7EQV3|E7EQV3_HUMAN" 19 1260.6033 1.46 78323 8068 2 1260.606888 631.3089 Polyadenylate-binding protein 4 OS=Homo sapiens OX=9606 GN=PABPC4 PE=1 SV=1 8.8 1805 - 642981 - - - 2.8145 - 1.891 0.538 - 369.9 1 2 0 0.0035 10 0 0 0 1.24E+07 8.50E+06 - - - 4.7919 1 221125_WJC_METTL3_EV_vs_WT_F06.08070.08070.3 0.00671 13/48 K.LKPAHEGLVATVK.E "sp|Q9Y618|NCOR2_HUMAN,tr|C9JQE8|C9JQE8_HUMAN,tr|C9J7T7|C9J7T7_HUMAN,tr|C9JE98|C9JE98_HUMAN,tr|C9J0Q5|C9J0Q5_HUMAN,tr|A0A384DVL6|A0A384DVL6_HUMAN" 6 1361.8031 1.9 78325 8070 3 1361.802681 454.9416 Nuclear receptor corepressor 2 OS=Homo sapiens OX=9606 GN=NCOR2 PE=1 SV=3 8.6 1805.2 - 1.43E+06 - - - -0.2967 - 2.539 0.465 - 120.4 1 2 0 -0.0004 13 0 0 0 3.87E+07 2.03E+07 - - - 6.2505 1 221125_WJC_METTL3_EV_vs_WT_F06.08072.08072.2 5.54E-07 20-Oct R.VADNAQQQYVR.S sp|Q8TDD1|DDX54_HUMAN 1 1290.6317 1.46 78327 8072 2 1290.63342 646.3231 ATP-dependent RNA helicase DDX54 OS=Homo sapiens OX=9606 GN=DDX54 PE=1 SV=2 5.81 1805.5 - 404890 - - - 1.3613 - 2.472 0.592 - 401.3 1 2 0 0.0018 11 0 0 0 1.31E+07 8.97E+06 - - - 5.8613 0.9767 221125_WJC_METTL3_EV_vs_WT_F06.08074.08074.2 0.307 16-May R.WHPYTNTAR.K "sp|Q96G21|IMP4_HUMAN,tr|E7ENR5|E7ENR5_HUMAN,tr|H0Y714|H0Y714_HUMAN" 3 1144.5414 1.46 78328 8074 2 1144.543289 573.278 U3 small nucleolar ribonucleoprotein protein IMP4 OS=Homo sapiens OX=9606 GN=IMP4 PE=1 SV=1 8.75 1805.7 - 642150 - - - 1.6583 - 1.086 0.161 - 100.9 1 2 0 0.0019 9 0 0 0 1.69E+07 1.16E+07 - - - 0.4682 1 221125_WJC_METTL3_EV_vs_WT_F06.08077.08077.2 1.19E-05 16/22 L.MELHGEGSSSGK[136.11].A "sp|P61247|RS3A_HUMAN,tr|D6R9B6|D6R9B6_HUMAN,tr|H0Y9Y4|H0Y9Y4_HUMAN,tr|D6RAT0|D6RAT0_HUMAN,tr|D6RG13|D6RG13_HUMAN" 5 1225.5489 1.13 78330 8077 2 1225.547185 613.7817 40S ribosomal protein S3a OS=Homo sapiens OX=9606 GN=RPS3A PE=1 SV=2 5.38 1806 - 978881 - - - -1.3594 - 2.488 0.6 - 887.8 1 1 0 -0.0017 12 0 0 0 1.84E+07 1.62E+07 - - - 5.8703 0.9759 221125_WJC_METTL3_EV_vs_WT_F06.08078.08078.2 4.44E-05 20-Sep M.ELHGEGSSSGK[136.11].A "sp|P61247|RS3A_HUMAN,tr|D6R9B6|D6R9B6_HUMAN,tr|H0Y9Y4|H0Y9Y4_HUMAN,tr|D6RAT0|D6RAT0_HUMAN,tr|D6RG13|D6RG13_HUMAN" 5 1094.5084 0.001 78331 8078 2 1094.509326 548.2615 40S ribosomal protein S3a OS=Homo sapiens OX=9606 GN=RPS3A PE=1 SV=2 5.4 1806.1 - 492169 - - - 0.8771 - 1.758 0.393 - 220.4 1 1 0 0.001 11 0 0 0 0.00E+00 5.03E+06 - - - 3.4696 0.9874 221125_WJC_METTL3_EV_vs_WT_F06.08081.08081.3 0.0488 Oct-40 R.LLEVQGSR[166.11]PGK[136.11].N "sp|P62136|PP1A_HUMAN,tr|E9PMD7|E9PMD7_HUMAN" 2 1200.6945 1.28 78332 8081 3 1200.696266 401.2388 Serine\threonine-protein phosphatase PP1-alpha catalytic subunit OS=Homo sapiens OX=9606 GN=PPP1CA PE=1 SV=1 8.75 1806.5 - 2.03E+06 - - - 1.4367 - 1.418 0.209 - 74.1 1 2 0 0.0017 11 0 0 0 3.63E+07 2.82E+07 - - - 1.8618 0.9987 221125_WJC_METTL3_EV_vs_WT_F06.08083.08083.3 0.00489 Dec-36 R.QLQELEKDER.E sp|P19474|RO52_HUMAN 1 1286.6466 1.75 78334 8083 3 1286.647005 429.8895 E3 ubiquitin-protein ligase TRIM21 OS=Homo sapiens OX=9606 GN=TRIM21 PE=1 SV=1 4.41 1806.7 - 1.53E+06 - - - 0.2806 - 2.014 0.332 - 300.7 1 2 1 0.0004 10 0 0 0 5.04E+07 2.88E+07 - - - 4.286 0.9927 221125_WJC_METTL3_EV_vs_WT_F06.08084.08084.3 0.0999 Nov-36 R.QLQELEK[136.11]DER[166.11].E sp|P19474|RO52_HUMAN 1 1304.6691 1.82 78335 8084 3 1304.670483 435.897 E3 ubiquitin-protein ligase TRIM21 OS=Homo sapiens OX=9606 GN=TRIM21 PE=1 SV=1 4.41 1806.8 - 1.45E+06 - - - 1.0493 - 1.807 0.251 - 147 1 2 1 0.0014 10 0 0 0 4.99E+07 2.75E+07 - - - 3.066 0.9519 221125_WJC_METTL3_EV_vs_WT_F06.08090.08090.2 0.0294 12-Jul Y.GNSPLHR[166.11].F "sp|P26599|PTBP1_HUMAN,sp|Q9UKA9|PTBP2_HUMAN,tr|A0A0U1RRM4|A0A0U1RRM4_HUMAN,tr|A0A6Q8PEZ3|A0A6Q8PEZ3_HUMAN,tr|A6NLN1|A6NLN1_HUMAN,tr|K7ELW5|K7ELW5_HUMAN,tr|A0A7I2RVZ4|A0A7I2RVZ4_HUMAN,tr|A0A0D9SF20|A0A0D9SF20_HUMAN,tr|A0A6Q8PFE6|A0A6Q8PFE6_HUMAN,tr|A0A6Q8PFC0|A0A6Q8PFC0_HUMAN,tr|A0A7I2V621|A0A7I2V621_HUMAN,tr|A0A6Q8PH82|A0A6Q8PH82_HUMAN,tr|A0A087WUW5|A0A087WUW5_HUMAN" 13 789.4121 0.91 78339 8090 2 789.412537 395.7133 Polypyrimidine tract-binding protein 1 OS=Homo sapiens OX=9606 GN=PTBP1 PE=1 SV=1 9.76 1807.5 - 7.67E+06 - - - 0.5472 - 1.533 0.301 - 281.7 1 1 0 0.0004 7 0 0 0 8.07E+07 8.91E+07 - - - 2.6177 0.994 221125_WJC_METTL3_EV_vs_WT_F06.08095.08095.2 0.000102 13/18 A.PGAEFAPNK[136.11]R[166.11].R "sp|Q15233|NONO_HUMAN,tr|A0A7I2V535|A0A7I2V535_HUMAN,tr|A0A7I2V4K9|A0A7I2V4K9_HUMAN,tr|A0A7I2V4J2|A0A7I2V4J2_HUMAN,tr|A0A7I2V5Y7|A0A7I2V5Y7_HUMAN" 5 1103.5843 1.11 78344 8095 2 1103.583395 552.7994 Non-POU domain-containing octamer-binding protein OS=Homo sapiens OX=9606 GN=NONO PE=1 SV=4 9.18 1807.8 - 1.92E+06 - - - -0.7856 - 2.505 0.517 - 982.4 1 1 0 -0.0009 10 0 0 0 5.08E+07 4.57E+07 - - - 5.4225 0.9998 221125_WJC_METTL3_EV_vs_WT_F06.08097.08097.2 0.00138 20-Oct R.SNLNMNAAGNR.N sp|Q9H7E2|TDRD3_HUMAN 1 1160.5357 999 78346 8097 2 1160.535973 581.2751 Tudor domain-containing protein 3 OS=Homo sapiens OX=9606 GN=TDRD3 PE=1 SV=1 9.47 1808 - 1.22E+06 - - - 0.2749 - 2.155 0.437 - 354.9 1 2 0 0.0003 11 0 0 0 1.56E+07 0.00E+00 - - - 4.3456 0.9832 221125_WJC_METTL3_EV_vs_WT_F06.08101.08101.2 1.51 16-Jul K.KPEPPVNLK.Y "sp|O60271|JIP4_HUMAN,tr|A0A087X2D8|A0A087X2D8_HUMAN" 2 1020.5968 2.23 78350 8101 2 1020.597569 511.3057 C-Jun-amino-terminal kinase-interacting protein 4 OS=Homo sapiens OX=9606 GN=SPAG9 PE=1 SV=4 8.59 1808.5 - 422974 - - - 0.7721 - 1.195 0.113 - 153.2 1 2 0 0.0008 9 0 0 0 1.69E+07 7.59E+06 - - - 0.3908 0.9615 221125_WJC_METTL3_EV_vs_WT_F06.08106.08106.2 0.0329 12-Jul Y.GNSPLHR.F "sp|P26599|PTBP1_HUMAN,sp|Q9UKA9|PTBP2_HUMAN,tr|A0A0U1RRM4|A0A0U1RRM4_HUMAN,tr|A0A6Q8PEZ3|A0A6Q8PEZ3_HUMAN,tr|A6NLN1|A6NLN1_HUMAN,tr|K7ELW5|K7ELW5_HUMAN,tr|A0A7I2RVZ4|A0A7I2RVZ4_HUMAN,tr|A0A0D9SF20|A0A0D9SF20_HUMAN,tr|A0A6Q8PFE6|A0A6Q8PFE6_HUMAN,tr|A0A6Q8PFC0|A0A6Q8PFC0_HUMAN,tr|A0A7I2V621|A0A7I2V621_HUMAN,tr|A0A6Q8PH82|A0A6Q8PH82_HUMAN,tr|A0A087WUW5|A0A087WUW5_HUMAN" 13 779.4038 1.12 78353 8106 2 779.404135 390.7092 Polypyrimidine tract-binding protein 1 OS=Homo sapiens OX=9606 GN=PTBP1 PE=1 SV=1 9.76 1809.1 - 9.10E+06 - - - 0.3849 - 1.569 0.315 - 407.6 1 1 0 0.0003 7 0 0 0 1.80E+08 1.61E+08 - - - 2.7947 0.9945 221125_WJC_METTL3_EV_vs_WT_F06.08109.08109.2 0.000431 18-Dec A.PGAEFAPNKR.R "sp|Q15233|NONO_HUMAN,tr|A0A7I2V535|A0A7I2V535_HUMAN,tr|A0A7I2V4K9|A0A7I2V4K9_HUMAN,tr|A0A7I2V4J2|A0A7I2V4J2_HUMAN,tr|A0A7I2V5Y7|A0A7I2V5Y7_HUMAN" 5 1085.5618 1.11 78356 8109 2 1085.561219 543.7882 Non-POU domain-containing octamer-binding protein OS=Homo sapiens OX=9606 GN=NONO PE=1 SV=4 9.18 1809.3 - 2.62E+06 - - - -0.5278 - 2.449 0.532 - 909.3 1 1 0 -0.0006 10 0 0 0 5.08E+07 4.57E+07 - - - 5.4703 0.9999 221125_WJC_METTL3_EV_vs_WT_F06.08112.08112.2 0.000344 13/22 R.AAPGAEFAPNK[136.11]R[166.11].R "sp|Q15233|NONO_HUMAN,tr|A0A7I2V535|A0A7I2V535_HUMAN,tr|A0A7I2V4K9|A0A7I2V4K9_HUMAN,tr|A0A7I2V4J2|A0A7I2V4J2_HUMAN,tr|A0A7I2V5Y7|A0A7I2V5Y7_HUMAN" 5 1245.6585 2.14 78359 8112 2 1245.659397 623.8365 Non-POU domain-containing octamer-binding protein OS=Homo sapiens OX=9606 GN=NONO PE=1 SV=4 8.79 1809.5 - 2.01E+06 - - - 0.7281 - 2.041 0.522 - 508.2 1 2 0 0.0009 12 0 0 0 8.04E+07 3.76E+07 - - - 4.7734 0.9743 221125_WJC_METTL3_EV_vs_WT_F06.08114.08114.2 0.00702 14-Sep D.YGNSPLHR[166.11].F "sp|P26599|PTBP1_HUMAN,tr|A0A0U1RRM4|A0A0U1RRM4_HUMAN,tr|A6NLN1|A6NLN1_HUMAN,tr|K7ELW5|K7ELW5_HUMAN,tr|A0A0D9SF20|A0A0D9SF20_HUMAN,tr|A0A7I2V621|A0A7I2V621_HUMAN,tr|A0A087WUW5|A0A087WUW5_HUMAN" 7 952.4754 0.66 78361 8114 2 952.476406 477.245 Polypyrimidine tract-binding protein 1 OS=Homo sapiens OX=9606 GN=PTBP1 PE=1 SV=1 8.75 1809.7 - 1.37E+06 - - - 1.0205 - 1.735 0.375 - 270.6 1 1 0 0.001 8 0 0 0 2.16E+07 3.27E+07 - - - 3.4723 0.9975 221125_WJC_METTL3_EV_vs_WT_F06.08116.08116.3 0.00751 Oct-32 R.AR[166.11]YEDPTLR[166.11].N "sp|Q6W2J9|BCOR_HUMAN,tr|H7BZ37|H7BZ37_HUMAN,tr|A1A564|A1A564_HUMAN,tr|H7C2V9|H7C2V9_HUMAN,tr|H7BYY2|H7BYY2_HUMAN,tr|H7C231|H7C231_HUMAN" 6 1139.5838 0.001 78363 8116 3 1139.584558 380.8685 BCL-6 corepressor OS=Homo sapiens OX=9606 GN=BCOR PE=1 SV=1 6.11 1809.9 - 904888 - - - 0.6546 - 1.842 0.304 - 179 1 2 1 0.0007 9 0 0 0 0.00E+00 1.06E+07 - - - 3.7701 0.9972 221125_WJC_METTL3_EV_vs_WT_F06.08118.08118.2 0.000223 18-Oct R.QLQELEK[136.11]DER[166.11].E sp|P19474|RO52_HUMAN 1 1304.6691 1.75 78365 8118 2 1304.669328 653.3418 E3 ubiquitin-protein ligase TRIM21 OS=Homo sapiens OX=9606 GN=TRIM21 PE=1 SV=1 4.41 1810.2 - 277213 - - - 0.164 - 1.953 0.395 - 407.9 1 2 1 0.0002 10 0 0 0 3.41E+06 1.95E+06 - - - 3.8268 0.9999 221125_WJC_METTL3_EV_vs_WT_F06.08124.08124.3 4.27E-05 14/44 K.VMEEEGLKDEEK.R sp|Q15208|STK38_HUMAN 1 1434.6548 4.34 78369 8124 3 1434.655247 479.2256 Serine\threonine-protein kinase 38 OS=Homo sapiens OX=9606 GN=STK38 PE=1 SV=1 4.14 1810.9 - 4.03E+06 - - - 0.2935 - 2.939 0.49 - 298.6 1 2 1 0.0004 12 0 0 0 1.39E+08 3.19E+07 - - - 6.9911 0.9998 221125_WJC_METTL3_EV_vs_WT_F06.08126.08126.3 0.000993 14/44 K.VMEEEGLK[136.11]DEEK[136.11].R sp|Q15208|STK38_HUMAN 1 1450.6832 4.34 78371 8126 3 1450.683035 484.5684 Serine\threonine-protein kinase 38 OS=Homo sapiens OX=9606 GN=STK38 PE=1 SV=1 4.14 1811.1 - 1.07E+06 - - - -0.1317 - 2.619 0.423 - 262.2 1 2 1 -0.0002 12 0 0 0 1.39E+08 3.19E+07 - - - 5.9247 0.9979 221125_WJC_METTL3_EV_vs_WT_F06.08127.08127.2 0.012 14-Aug K.DLNEQFK[136.11]K[136.11].H "sp|Q13616|CUL1_HUMAN,tr|A0A0C4DGX4|A0A0C4DGX4_HUMAN,tr|A0A590UJ21|A0A590UJ21_HUMAN,tr|A0A590UJ50|A0A590UJ50_HUMAN,tr|A0A590UJR3|A0A590UJR3_HUMAN,tr|A0A590UJ56|A0A590UJ56_HUMAN,tr|A0A590UJC4|A0A590UJC4_HUMAN,tr|A0A590UK34|A0A590UK34_HUMAN" 8 1036.5524 0.47 78372 8127 2 1036.550046 519.2835 Cullin-1 OS=Homo sapiens OX=9606 GN=CUL1 PE=1 SV=2 6.07 1811.2 - 1.06E+06 - - - -2.2806 - 1.406 0.34 - 182.5 1 2 0 -0.0024 8 0 0 0 7.10E+06 1.49E+07 - - - 2.5792 0.9998 221125_WJC_METTL3_EV_vs_WT_F06.08128.08128.2 4.41E-05 16-Oct R.QTFENQVNR.L "sp|P24928|RPB1_HUMAN,tr|A0A6Q8PGB0|A0A6Q8PGB0_HUMAN" 2 1134.5418 1.26 78373 8128 2 1134.54067 568.2782 DNA-directed RNA polymerase II subunit RPB1 OS=Homo sapiens OX=9606 GN=POLR2A PE=1 SV=2 6 1811.4 - 989888 - - - -0.9828 - 1.968 0.475 - 425.8 1 2 0 -0.0011 9 0 0 0 5.54E+07 4.39E+07 - - - 4.5076 0.9882 221125_WJC_METTL3_EV_vs_WT_F06.08129.08129.2 1.35 14-Jun K.DLNEQFKK.H "sp|Q13616|CUL1_HUMAN,tr|A0A0C4DGX4|A0A0C4DGX4_HUMAN,tr|A0A590UJ21|A0A590UJ21_HUMAN,tr|A0A590UJ50|A0A590UJ50_HUMAN,tr|A0A590UJR3|A0A590UJR3_HUMAN,tr|A0A590UJ56|A0A590UJ56_HUMAN,tr|A0A590UJC4|A0A590UJC4_HUMAN,tr|A0A590UK34|A0A590UK34_HUMAN" 8 1020.524 0.47 78374 8129 2 1020.524325 511.2693 Cullin-1 OS=Homo sapiens OX=9606 GN=CUL1 PE=1 SV=2 6.07 1811.5 - 663297 - - - 0.3087 - 1.029 0.19 - 103 1 2 0 0.0003 8 0 0 0 7.10E+06 1.49E+07 - - - 0.5305 0.9982 221125_WJC_METTL3_EV_vs_WT_F06.08130.08130.2 6.83E-07 14/22 K.VMEEEGLKDEEK.R sp|Q15208|STK38_HUMAN 1 1434.6548 7.97 78375 8130 2 1434.657153 718.3347 Serine\threonine-protein kinase 38 OS=Homo sapiens OX=9606 GN=STK38 PE=1 SV=1 4.14 1811.6 - 480505 - - - 1.622 - 2.74 0.524 - 629.6 1 2 1 0.0023 12 0 0 0 2.37E+07 2.97E+06 - - - 5.5626 0.9993 221125_WJC_METTL3_EV_vs_WT_F06.08131.08131.2 0.0171 20-Oct K.RGDTVATLSER.V sp|P22102|PUR2_HUMAN 1 1203.6208 0.43 78376 8131 2 1203.622739 602.8177 Trifunctional purine biosynthetic protein adenosine-3 OS=Homo sapiens OX=9606 GN=GART PE=1 SV=1 6.07 1811.7 - 468880 - - - 1.6409 - 1.82 0.353 - 87.1 1 2 0 0.002 11 0 0 0 3.50E+06 8.05E+06 - - - 3.2676 0.991 221125_WJC_METTL3_EV_vs_WT_F06.08132.08132.2 0.00126 18-Dec R.QLQELEKDER.E sp|P19474|RO52_HUMAN 1 1286.6466 1.75 78377 8132 2 1286.649692 644.3306 E3 ubiquitin-protein ligase TRIM21 OS=Homo sapiens OX=9606 GN=TRIM21 PE=1 SV=1 4.41 1811.9 - 448333 - - - 2.3689 - 2.205 0.329 - 667.4 1 2 1 0.003 10 0 0 0 3.41E+06 1.95E+06 - - - 3.6772 1 221125_WJC_METTL3_EV_vs_WT_F06.08133.08133.3 1.00E-05 Dec-52 K.C[160.03]LPPSEAASDNHLK.K "sp|Q14241|ELOA1_HUMAN,tr|A0A024RAC6|A0A024RAC6_HUMAN" 2 1537.7195 0.71 78378 8133 3 1537.719135 513.5804 Elongin-A OS=Homo sapiens OX=9606 GN=ELOA PE=1 SV=2 5.32 1812 - 344342 - - - -0.2322 - 2.132 0.487 - 69.4 1 2 0 -0.0004 14 0 0 0 1.11E+07 1.56E+07 - - - 5.9814 0.9998 221125_WJC_METTL3_EV_vs_WT_F06.08139.08139.3 0.0494 17/48 K.VLATVTK[136.11]PVGGDK[136.11].N "sp|Q02878|RL6_HUMAN,tr|F8VZ45|F8VZ45_HUMAN,tr|F8VWR1|F8VWR1_HUMAN,tr|F8VU16|F8VU16_HUMAN,tr|U3KQR5|U3KQR5_HUMAN,tr|F8VZA3|F8VZA3_HUMAN" 6 1299.7733 0.73 78382 8139 3 1299.772378 434.265 60S ribosomal protein L6 OS=Homo sapiens OX=9606 GN=RPL6 PE=1 SV=3 8.56 1812.6 - 2.59E+06 - - - -0.7109 - 2.389 0.318 - 318.4 1 2 0 -0.0009 13 0 0 0 3.43E+07 4.68E+07 - - - 4.4463 0.903 221125_WJC_METTL3_EV_vs_WT_F06.08140.08140.2 1.11 14-Aug Q.DSGHLDLR[166.11].N "sp|Q86U44|MTA70_HUMAN,tr|B4E349|B4E349_HUMAN,tr|F5H6D8|F5H6D8_HUMAN,tr|B4DTN4|B4DTN4_HUMAN" 4 921.4544 0.001 78383 8140 2 921.453567 461.7345 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 5.21 1812.7 - 3.04E+06 - - - -0.8649 - 1.894 0.138 - 252.3 1 1 0 -0.0008 8 0 0 0 0.00E+00 6.30E+07 - - - 1.9863 0.9919 221125_WJC_METTL3_EV_vs_WT_F06.08141.08141.3 0.0282 Oct-40 K.ALNRPPTYPTK.Y "sp|P55010|IF5_HUMAN,tr|H0YM54|H0YM54_HUMAN,tr|H0YLZ1|H0YLZ1_HUMAN,tr|H0YMJ8|H0YMJ8_HUMAN,tr|H0YK11|H0YK11_HUMAN,tr|H0YN40|H0YN40_HUMAN" 6 1256.6877 1.03 78384 8141 3 1256.684879 419.9032 Eukaryotic translation initiation factor 5 OS=Homo sapiens OX=9606 GN=EIF5 PE=1 SV=2 9.99 1812.7 - 2.29E+06 - - - -2.2615 - 1.707 0.212 - 126 1 2 0 -0.0028 11 0 0 0 1.52E+08 1.47E+08 - - - 2.4219 0.9996 221125_WJC_METTL3_EV_vs_WT_F06.08144.08144.2 0.071 20-Aug R.VSPSTSYTPSR[166.11].H sp|Q9BTE3|MCMBP_HUMAN 1 1190.5807 0.66 78387 8144 2 1190.579543 596.2976 Mini-chromosome maintenance complex-binding protein OS=Homo sapiens OX=9606 GN=MCMBP PE=1 SV=2 8.72 1813.1 - 944701 - - - -0.9609 - 1.92 0.349 - 314.8 1 2 0 -0.0011 11 0 0 0 2.61E+07 3.96E+07 - - - 3.383 0.9999 221125_WJC_METTL3_EV_vs_WT_F06.08146.08146.2 8.30E-05 14/24 R.TVTAAGAENIQQK[136.11].T sp|Q29RF7|PDS5A_HUMAN 1 1337.703 0.71 78389 8146 2 1337.702394 669.8588 Sister chromatid cohesion protein PDS5 homolog A OS=Homo sapiens OX=9606 GN=PDS5A PE=1 SV=1 5.66 1813.4 - 603557 - - - -0.4859 - 2.725 0.513 - 532.4 1 2 0 -0.0006 13 0 0 0 9.15E+06 1.29E+07 - - - 5.4027 0.9999 221125_WJC_METTL3_EV_vs_WT_F06.08155.08155.3 3.71E-05 13/44 R.AGPPHTC[160.03]PLC[160.03]PR.R sp|Q9UK33|ZN580_HUMAN 1 1361.6333 0.99 78396 8155 3 1361.629738 454.885 Zinc finger protein 580 OS=Homo sapiens OX=9606 GN=ZNF580 PE=1 SV=1 8.12 1814.4 - 970869 - - - -2.5866 - 2.353 0.504 - 209.5 1 2 0 -0.0035 12 0 0 0 1.73E+07 1.75E+07 - - - 6.53 0.9998 221125_WJC_METTL3_EV_vs_WT_F06.08156.08156.2 9.11E-06 13/24 R.TVTAAGAENIQQK.T sp|Q29RF7|PDS5A_HUMAN 1 1329.6888 0.71 78397 8156 2 1329.690826 665.8517 Sister chromatid cohesion protein PDS5 homolog A OS=Homo sapiens OX=9606 GN=PDS5A PE=1 SV=1 5.66 1814.5 - 765044 - - - 1.4906 - 2.328 0.494 - 440.6 1 2 0 0.002 13 0 0 0 9.15E+06 1.29E+07 - - - 4.8578 0.9999 221125_WJC_METTL3_EV_vs_WT_F06.08158.08158.3 9.82E-05 Dec-44 R.AGPPHTC[160.03]PLC[160.03]PR[166.11].R sp|Q9UK33|ZN580_HUMAN 1 1371.6415 0.93 78399 8158 3 1371.638541 458.2211 Zinc finger protein 580 OS=Homo sapiens OX=9606 GN=ZNF580 PE=1 SV=1 8.12 1814.8 - 628899 - - - -2.1791 - 2.356 0.462 - 243.3 1 2 0 -0.003 12 0 0 0 1.67E+07 1.80E+07 - - - 6.0654 0.9993 221125_WJC_METTL3_EV_vs_WT_F06.08162.08162.2 0.049 16-Aug R.VTDALNATR.A "sp|P10809|CH60_HUMAN,tr|A0A7I2V2X6|A0A7I2V2X6_HUMAN,tr|A0A7I2YQK6|A0A7I2YQK6_HUMAN,tr|A0A7I2V599|A0A7I2V599_HUMAN" 4 959.5036 1.3 78401 8162 2 959.50554 480.7591 "60 kDa heat shock protein, mitochondrial OS=Homo sapiens OX=9606 GN=HSPD1 PE=1 SV=2" 5.81 1815.2 - 3.72E+06 - - - 2.0125 - 1.889 0.359 - 176.6 1 2 0 0.0019 9 0 0 0 1.00E+08 7.71E+07 - - - 3.5321 0.9999 221125_WJC_METTL3_EV_vs_WT_F06.08163.08163.2 0.00113 16-Oct R.VTDALNATR[166.11].A "sp|P10809|CH60_HUMAN,tr|A0A7I2V2X6|A0A7I2V2X6_HUMAN,tr|A0A7I2YQK6|A0A7I2YQK6_HUMAN,tr|A0A7I2V599|A0A7I2V599_HUMAN" 4 969.5119 1.3 78402 8163 2 969.511198 485.7632 "60 kDa heat shock protein, mitochondrial OS=Homo sapiens OX=9606 GN=HSPD1 PE=1 SV=2" 5.81 1815.3 - 3.45E+06 - - - -0.7024 - 2.241 0.478 - 301.3 1 2 0 -0.0007 9 0 0 0 1.00E+08 7.71E+07 - - - 4.9058 0.9965 221125_WJC_METTL3_EV_vs_WT_F06.08164.08164.2 0.057 18-Nov R.RISAVSVAER.V sp|Q08211|DHX9_HUMAN 1 1086.6146 0.9 78403 8164 2 1086.61315 544.3146 ATP-dependent RNA helicase A OS=Homo sapiens OX=9606 GN=DHX9 PE=1 SV=4 9.6 1815.4 - 1.61E+06 - - - -1.2939 - 1.361 0.232 - 172.8 1 2 0 -0.0014 10 0 0 0 2.71E+07 3.03E+07 - - - 1.6144 0.7971 221125_WJC_METTL3_EV_vs_WT_F06.08167.08167.2 0.105 18-Nov Y.SC[160.03]VGVFQHGK[136.11].V "sp|P54652|HSP72_HUMAN,sp|P0DMV8|HS71A_HUMAN,sp|P34931|HS71L_HUMAN,sp|P11142|HSP7C_HUMAN,sp|P0DMV9|HS71B_HUMAN,tr|E9PQQ4|E9PQQ4_HUMAN,tr|E9PNE6|E9PNE6_HUMAN,tr|E9PKE3|E9PKE3_HUMAN,tr|E9PLF4|E9PLF4_HUMAN,tr|Q53FA3|Q53FA3_HUMAN,tr|E9PI65|E9PI65_HUMAN,tr|V9GZ37|V9GZ37_HUMAN,tr|E9PK54|E9PK54_HUMAN,tr|E9PN25|E9PN25_HUMAN,tr|E9PPY6|E9PPY6_HUMAN,tr|E9PQK7|E9PQK7_HUMAN,tr|A0A0G2JIW1|A0A0G2JIW1_HUMAN" 17 1125.5481 0.09 78406 8167 2 1125.543937 563.7813 Heat shock-related 70 kDa protein 2 OS=Homo sapiens OX=9606 GN=HSPA2 PE=1 SV=1 7.97 1815.7 - 693381 - - - -3.6658 - 1.712 0.316 - 400.3 1 1 0 -0.0041 10 0 0 0 5.21E+06 5.53E+07 - - - 2.8745 0.998 221125_WJC_METTL3_EV_vs_WT_F06.08168.08168.2 0.000386 22-Aug K.VMEEEGLK[136.11]DEEK[136.11].R sp|Q15208|STK38_HUMAN 1 1450.6832 7.66 78407 8168 2 1450.684323 726.3489 Serine\threonine-protein kinase 38 OS=Homo sapiens OX=9606 GN=STK38 PE=1 SV=1 4.14 1815.9 - 340459 - - - 0.7562 - 1.963 0.502 - 167.5 1 2 1 0.0011 12 0 0 0 2.28E+07 2.97E+06 - - - 4.5231 0.993 221125_WJC_METTL3_EV_vs_WT_F06.08170.08170.2 0.944 14-Sep K.SEISELRR.T "sp|Q04695|K1C17_HUMAN,sp|P02533|K1C14_HUMAN,tr|F5GWP8|F5GWP8_HUMAN" 3 988.5302 2324.57 78408 8170 2 988.529892 495.2724 "Keratin, type I cytoskeletal 17 OS=Homo sapiens OX=9606 GN=KRT17 PE=1 SV=2" 5.86 1816.1 - 1.84E+07 - - - -0.2691 - 1.372 0.118 - 178.1 1 2 0 -0.0003 8 0 0 0 1.28E+09 5.49E+05 - - - 0.8663 0.9997 221125_WJC_METTL3_EV_vs_WT_F06.08174.08174.3 0.00643 Dec-48 R.EGVGPVEQEGVRR.A sp|Q969Y2|GTPB3_HUMAN 1 1410.7215 1.72 78411 8174 3 1410.720906 471.2478 "tRNA modification GTPase GTPBP3, mitochondrial OS=Homo sapiens OX=9606 GN=GTPBP3 PE=1 SV=2" 4.79 1816.4 - 2.21E+06 - - - -0.4501 - 2.16 0.33 - 247.2 1 2 0 -0.0006 13 0 0 0 5.33E+07 3.11E+07 - - - 4.307 0.9996 221125_WJC_METTL3_EV_vs_WT_F06.08180.08180.2 0.00579 18-Dec R.R[166.11]ISAVSVAER[166.11].V sp|Q08211|DHX9_HUMAN 1 1106.6311 0.88 78415 8180 2 1106.630626 554.3228 ATP-dependent RNA helicase A OS=Homo sapiens OX=9606 GN=DHX9 PE=1 SV=4 9.6 1817.2 - 1.49E+06 - - - -0.4247 - 1.952 0.327 - 204.6 1 2 0 -0.0005 10 0 0 0 2.70E+07 3.09E+07 - - - 3.3231 0.9945 221125_WJC_METTL3_EV_vs_WT_F06.08181.08181.3 0.218 Aug-40 K.ALNR[166.11]PPTYPTK[136.11].Y "sp|P55010|IF5_HUMAN,tr|H0YM54|H0YM54_HUMAN,tr|H0YLZ1|H0YLZ1_HUMAN,tr|H0YMJ8|H0YMJ8_HUMAN,tr|H0YK11|H0YK11_HUMAN,tr|H0YN40|H0YN40_HUMAN" 6 1274.7102 1.12 78416 8181 3 1274.709357 425.9107 Eukaryotic translation initiation factor 5 OS=Homo sapiens OX=9606 GN=EIF5 PE=1 SV=2 9.99 1817.3 - 4.76E+06 - - - -0.6543 - 1.522 0.219 - 84.6 1 2 0 -0.0008 11 0 0 0 1.45E+08 1.30E+08 - - - 2.1746 0.9998 221125_WJC_METTL3_EV_vs_WT_F06.08185.08185.2 0.000432 20-Oct K.ALNRPPTYPTK.Y "sp|P55010|IF5_HUMAN,tr|H0YM54|H0YM54_HUMAN,tr|H0YLZ1|H0YLZ1_HUMAN,tr|H0YMJ8|H0YMJ8_HUMAN,tr|H0YK11|H0YK11_HUMAN,tr|H0YN40|H0YN40_HUMAN" 6 1256.6877 1.21 78420 8185 2 1256.68624 629.3511 Eukaryotic translation initiation factor 5 OS=Homo sapiens OX=9606 GN=EIF5 PE=1 SV=2 9.99 1817.7 - 404281 - - - -1.1785 - 2.16 0.469 - 401.5 1 2 0 -0.0015 11 0 0 0 1.19E+07 9.79E+06 - - - 4.5879 0.9988 221125_WJC_METTL3_EV_vs_WT_F06.08188.08188.2 0.019 18-Oct R.RLDTSLGSAR.T sp|Q9Y3D2|MSRB2_HUMAN 1 1074.5782 1.18 78421 8188 2 1074.57651 538.2964 "Methionine-R-sulfoxide reductase B2, mitochondrial OS=Homo sapiens OX=9606 GN=MSRB2 PE=1 SV=2" 9.6 1818.1 - 965115 - - - -1.5457 - 1.796 0.286 - 124.7 2 2 0 -0.0017 10 0 0 0 1.38E+07 1.16E+07 - - - 2.6529 0.9966 221125_WJC_METTL3_EV_vs_WT_F06.08190.08190.2 0.0101 20-Aug R.HSPLTQMGPAK.D "sp|Q9Y2Q9|RT28_HUMAN,tr|H0YAT2|H0YAT2_HUMAN,tr|U3KQQ8|U3KQQ8_HUMAN,tr|H7C5V3|H7C5V3_HUMAN,tr|H0YC42|H0YC42_HUMAN,tr|E5RGC7|E5RGC7_HUMAN" 6 1165.5914 1.52 78423 8190 2 1165.586529 583.803 "28S ribosomal protein S28, mitochondrial OS=Homo sapiens OX=9606 GN=MRPS28 PE=1 SV=1" 8.76 1818.4 - 454730 - - - -4.1601 - 1.628 0.425 - 129.2 1 2 0 -0.0048 11 0 0 0 1.19E+07 7.84E+06 - - - 3.4969 0.9987 221125_WJC_METTL3_EV_vs_WT_F06.08191.08191.2 0.00814 20-Jun K.ALNR[166.11]PPTYPTK[136.11].Y "sp|P55010|IF5_HUMAN,tr|H0YM54|H0YM54_HUMAN,tr|H0YLZ1|H0YLZ1_HUMAN,tr|H0YMJ8|H0YMJ8_HUMAN,tr|H0YK11|H0YK11_HUMAN,tr|H0YN40|H0YN40_HUMAN" 6 1274.7102 1.24 78424 8191 2 1274.709153 638.3624 Eukaryotic translation initiation factor 5 OS=Homo sapiens OX=9606 GN=EIF5 PE=1 SV=2 9.99 1818.5 - 382314 - - - -0.8143 - 1.569 0.268 - 143.1 1 2 0 -0.001 11 0 0 0 1.25E+07 1.01E+07 - - - 2.2387 0.9996 221125_WJC_METTL3_EV_vs_WT_F06.08192.08192.2 0.000458 18-Jul R.YQANNC[160.03]PIC[160.03]R.L "sp|O60291|MGRN1_HUMAN,sp|Q96PX1|RN157_HUMAN,tr|A0A3B3ISM3|A0A3B3ISM3_HUMAN,tr|B4DR12|B4DR12_HUMAN,tr|K7EIM7|K7EIM7_HUMAN,tr|K7EPJ5|K7EPJ5_HUMAN" 6 1294.5547 2.54 78425 8192 2 1294.551786 648.2846 E3 ubiquitin-protein ligase MGRN1 OS=Homo sapiens OX=9606 GN=MGRN1 PE=1 SV=2 8.06 1818.6 - 207837 - - - -2.2324 - 1.706 0.549 - 147.5 1 2 0 -0.0029 10 0 0 0 3.25E+06 1.28E+06 - - - 4.586 0.9985 221125_WJC_METTL3_EV_vs_WT_F06.08198.08198.2 0.00284 20-Sep R.FVPPQTSSGNR[166.11].F "sp|Q6KC79|NIPBL_HUMAN,tr|A0A590UJS4|A0A590UJS4_HUMAN" 2 1198.597 2.05 78428 8198 2 1198.593854 600.3058 Nipped-B-like protein OS=Homo sapiens OX=9606 GN=NIPBL PE=1 SV=2 9.75 1819.4 - 674800 - - - -2.6297 - 1.558 0.39 - 157.3 1 2 0 -0.0032 11 0 0 0 5.82E+07 2.85E+07 - - - 3.1201 0.9718 221125_WJC_METTL3_EV_vs_WT_F06.08202.08202.2 0.000889 16-Sep Y.TQSQFSAPR.D "sp|Q14444|CAPR1_HUMAN,tr|G3V153|G3V153_HUMAN" 2 1020.4989 1.12 78430 8202 2 1020.499381 511.2567 Caprin-1 OS=Homo sapiens OX=9606 GN=CAPRIN1 PE=1 SV=2 9.41 1819.9 - 591304 - - - 0.5125 - 1.568 0.38 - 396.3 1 1 0 0.0005 9 0 0 0 5.58E+06 5.00E+06 - - - 3.1488 0.9993 221125_WJC_METTL3_EV_vs_WT_F06.08207.08207.2 1.89E-05 12-Aug R.HYEDFPK.L sp|O94906|PRP6_HUMAN 1 934.4185 2.52 78434 8207 2 934.418708 468.2165 Pre-mRNA-processing factor 6 OS=Homo sapiens OX=9606 GN=PRPF6 PE=1 SV=1 5.32 1820.4 - 2.29E+06 - - - 0.2419 - 1.679 0.285 - 220.2 1 2 0 0.0002 7 0 0 0 6.75E+07 2.68E+07 - - - 2.7879 0.9991 221125_WJC_METTL3_EV_vs_WT_F06.08213.08213.2 0.00485 20-Sep R.FVPPQTSSGNR.F "sp|Q6KC79|NIPBL_HUMAN,tr|A0A590UJS4|A0A590UJS4_HUMAN" 2 1188.5887 1.6 78438 8213 2 1188.588302 595.3016 Nipped-B-like protein OS=Homo sapiens OX=9606 GN=NIPBL PE=1 SV=2 9.75 1821.1 - 1.53E+06 - - - -0.3651 - 1.678 0.272 - 143.3 1 2 0 -0.0004 11 0 0 0 4.14E+07 2.59E+07 - - - 2.4501 0.9998 221125_WJC_METTL3_EV_vs_WT_F06.08214.08214.2 0.046 16-Nov R.KEDMTYAVR.K "sp|Q07955|SRSF1_HUMAN,tr|J3KTL2|J3KTL2_HUMAN,tr|J3KSR8|J3KSR8_HUMAN" 3 1111.5332 1.05 78439 8214 2 1111.532891 556.7739 Serine\arginine-rich splicing factor 1 OS=Homo sapiens OX=9606 GN=SRSF1 PE=1 SV=2 6.07 1821.2 - 1.07E+06 - - - -0.2726 - 2.24 0.419 - 463.9 1 2 0 -0.0003 9 0 0 0 3.89E+07 3.70E+07 - - - 4.4688 1 221125_WJC_METTL3_EV_vs_WT_F06.08215.08215.2 4.94E-07 22-Dec K.VGGTSDVEVNEK[136.11].K "sp|P10809|CH60_HUMAN,tr|A0A7I2V2X6|A0A7I2V2X6_HUMAN,tr|A0A7I2YQK6|A0A7I2YQK6_HUMAN,tr|A0A7I2V599|A0A7I2V599_HUMAN" 4 1240.6027 1.08 78440 8215 2 1240.600302 621.3086 "60 kDa heat shock protein, mitochondrial OS=Homo sapiens OX=9606 GN=HSPD1 PE=1 SV=2" 4.14 1821.3 - 640820 - - - -1.9015 - 2.756 0.558 - 827.5 1 2 0 -0.0024 12 0 0 0 2.80E+07 2.58E+07 - - - 5.8291 0.9997 221125_WJC_METTL3_EV_vs_WT_F06.08216.08216.2 0.000433 16-Sep R.HENYDEALR.L sp|Q9HCS7|SYF1_HUMAN 1 1145.5102 1.43 78441 8216 2 1145.508586 573.7624 Pre-mRNA-splicing factor SYF1 OS=Homo sapiens OX=9606 GN=XAB2 PE=1 SV=2 4.65 1821.5 - 636883 - - - -1.3662 - 1.706 0.483 - 239.6 1 2 0 -0.0016 9 0 0 0 8.68E+06 6.07E+06 - - - 4.1533 0.9997 221125_WJC_METTL3_EV_vs_WT_F06.08217.08217.2 0.00112 20-Sep R.HSPLTQMGPAK[136.11].D "sp|Q9Y2Q9|RT28_HUMAN,tr|H0YAT2|H0YAT2_HUMAN,tr|U3KQQ8|U3KQQ8_HUMAN,tr|H7C5V3|H7C5V3_HUMAN,tr|H0YC42|H0YC42_HUMAN,tr|E5RGC7|E5RGC7_HUMAN" 6 1173.6056 1.45 78442 8217 2 1173.605719 587.8101 "28S ribosomal protein S28, mitochondrial OS=Homo sapiens OX=9606 GN=MRPS28 PE=1 SV=1" 8.76 1821.6 - 313818 - - - 0.1201 - 1.713 0.42 - 179.2 1 2 0 0.0001 11 0 0 0 8.36E+06 5.76E+06 - - - 3.5992 0.9874 221125_WJC_METTL3_EV_vs_WT_F06.08221.08221.3 3.37E-05 Nov-44 L.MTTVHAITATQK[136.11].T "sp|P04406|G3P_HUMAN,tr|E7EUT5|E7EUT5_HUMAN" 2 1308.6951 0.92 78445 8221 3 1308.694367 437.239 Glyceraldehyde-3-phosphate dehydrogenase OS=Homo sapiens OX=9606 GN=GAPDH PE=1 SV=3 8.52 1822 - 3.18E+06 - - - -0.5761 - 2.114 0.394 - 129.2 1 1 0 -0.0008 12 0 0 0 2.18E+08 2.36E+08 - - - 5.0075 1 221125_WJC_METTL3_EV_vs_WT_F06.08226.08226.2 8.21E-11 15/22 L.MTTVHAITATQK[136.11].T "sp|P04406|G3P_HUMAN,tr|E7EUT5|E7EUT5_HUMAN" 2 1308.6951 0.93 78450 8226 2 1308.695864 655.3548 Glyceraldehyde-3-phosphate dehydrogenase OS=Homo sapiens OX=9606 GN=GAPDH PE=1 SV=3 8.52 1822.5 - 478523 - - - 0.5677 - 2.885 0.636 - 928 1 1 0 0.0007 12 0 0 0 3.81E+07 4.09E+07 - - - 6.5261 0.9995 221125_WJC_METTL3_EV_vs_WT_F06.08227.08227.2 0.0014 18-Sep K.ENQIYSADEK[136.11].R "sp|Q5M9Q1|NKAPL_HUMAN,sp|Q8N5F7|NKAP_HUMAN,tr|A0A494C050|A0A494C050_HUMAN" 3 1203.5499 0.9 78451 8227 2 1203.552255 602.7822 NKAP-like protein OS=Homo sapiens OX=9606 GN=NKAPL PE=1 SV=3 4.14 1822.7 - 432995 - - - 1.9592 - 1.651 0.461 - 426.6 1 2 0 0.0024 10 0 0 0 6.66E+06 7.37E+06 - - - 3.8447 1 221125_WJC_METTL3_EV_vs_WT_F06.08228.08228.2 5.49E-07 15/22 L.MTTVHAITATQK.T "sp|P04406|G3P_HUMAN,tr|E7EUT5|E7EUT5_HUMAN" 2 1300.6809 0.93 78452 8228 2 1300.678931 651.3477 Glyceraldehyde-3-phosphate dehydrogenase OS=Homo sapiens OX=9606 GN=GAPDH PE=1 SV=3 8.52 1822.8 - 376175 - - - -1.53 - 2.941 0.594 - 1151.8 1 1 0 -0.002 12 0 0 0 3.81E+07 4.09E+07 - - - 6.266 0.992 221125_WJC_METTL3_EV_vs_WT_F06.08231.08231.3 8.41E-05 13/44 L.MTTVHAITATQK.T "sp|P04406|G3P_HUMAN,tr|E7EUT5|E7EUT5_HUMAN" 2 1300.6809 0.92 78454 8231 3 1300.68002 434.5676 Glyceraldehyde-3-phosphate dehydrogenase OS=Homo sapiens OX=9606 GN=GAPDH PE=1 SV=3 8.52 1823.1 - 7.10E+06 - - - -0.6927 - 2.26 0.417 - 219.1 1 1 0 -0.0009 12 0 0 0 2.17E+08 2.35E+08 - - - 5.449 0.9998 221125_WJC_METTL3_EV_vs_WT_F06.08233.08233.2 0.00273 16-Oct R.K[136.11]EDMTYAVR[166.11].K "sp|Q07955|SRSF1_HUMAN,tr|J3KTL2|J3KTL2_HUMAN,tr|J3KSR8|J3KSR8_HUMAN" 3 1129.5557 1.01 78455 8233 2 1129.555197 565.7851 Serine\arginine-rich splicing factor 1 OS=Homo sapiens OX=9606 GN=SRSF1 PE=1 SV=2 6.07 1823.3 - 2.61E+06 - - - -0.4134 - 2.179 0.427 - 352.5 1 2 0 -0.0005 9 0 0 0 3.81E+07 3.77E+07 - - - 4.448 0.9997 221125_WJC_METTL3_EV_vs_WT_F06.08237.08237.2 1.14E-05 18-Jul R.GDPC[160.03]NTIC[160.03]C[160.03]R.E sp|Q6P4A8|PLBL1_HUMAN 1 1251.4795 28.84 78459 8237 2 1251.481886 626.747 Phospholipase B-like 1 OS=Homo sapiens OX=9606 GN=PLBD1 PE=1 SV=2 5.82 1823.8 - 504067 - - - 1.9369 - 1.719 0.58 - 225.1 1 2 0 0.0024 10 0 0 0 1.40E+07 4.86E+05 - - - 4.8363 0.9998 221125_WJC_METTL3_EV_vs_WT_F06.08243.08243.2 0.00177 18-Oct R.EASFSPTDNK.F "sp|Q9C0J8|WDR33_HUMAN,tr|C9J8B4|C9J8B4_HUMAN" 2 1094.488 1.23 78463 8243 2 1094.487276 548.2513 pre-mRNA 3' end processing protein WDR33 OS=Homo sapiens OX=9606 GN=WDR33 PE=1 SV=2 4.37 1824.6 - 5.47E+06 - - - -0.6779 - 1.903 0.482 - 306.7 1 2 0 -0.0007 10 0 0 0 1.07E+08 8.64E+07 - - - 4.3968 0.9998 221125_WJC_METTL3_EV_vs_WT_F06.08244.08244.2 0.000555 20-Sep K.TPGPGAQSALR.A "sp|P62263|RS14_HUMAN,tr|A0A2R8Y811|A0A2R8Y811_HUMAN,tr|E5RH77|E5RH77_HUMAN" 3 1053.5567 1.51 78464 8244 2 1053.557224 527.7856 40S ribosomal protein S14 OS=Homo sapiens OX=9606 GN=RPS14 PE=1 SV=3 9.41 1824.6 - 2.79E+06 - - - 0.4907 - 1.857 0.439 - 251.7 1 2 0 0.0005 11 0 0 0 7.65E+07 5.07E+07 - - - 3.9577 0.9998 221125_WJC_METTL3_EV_vs_WT_F06.08246.08246.2 5.93E-05 20-Nov K.TPGPGAQSALR[166.11].A "sp|P62263|RS14_HUMAN,tr|A0A2R8Y811|A0A2R8Y811_HUMAN,tr|E5RH77|E5RH77_HUMAN" 3 1063.565 1.5 78466 8246 2 1063.565606 532.7898 40S ribosomal protein S14 OS=Homo sapiens OX=9606 GN=RPS14 PE=1 SV=3 9.41 1824.7 - 1.92E+06 - - - 0.5914 - 2.041 0.448 - 410.4 1 2 0 0.0006 11 0 0 0 7.95E+07 5.32E+07 - - - 4.2798 0.9957 221125_WJC_METTL3_EV_vs_WT_F06.08247.08247.2 0.72 16-Sep K.RSTVAQLVK.R "sp|P25705|ATPA_HUMAN,tr|K7ENJ4|K7ENJ4_HUMAN" 2 1000.6029 1.3 78467 8247 2 1000.602715 501.3087 "ATP synthase subunit alpha, mitochondrial OS=Homo sapiens OX=9606 GN=ATP5F1A PE=1 SV=1" 11 1824.8 - 1.73E+06 - - - -0.2139 - 1.728 0.08 - 365.6 1 2 0 -0.0002 9 0 0 0 2.64E+07 2.03E+07 - - - 1.2142 0.9999 221125_WJC_METTL3_EV_vs_WT_F06.08248.08248.3 3.23E-05 Nov-44 R.SQYEQLAEQNRK.D "sp|P13645|K1C10_HUMAN,tr|A0A1B0GVI3|A0A1B0GVI3_HUMAN" 2 1492.727 999 78468 8248 3 1492.726663 498.5829 "Keratin, type I cytoskeletal 10 OS=Homo sapiens OX=9606 GN=KRT10 PE=1 SV=6" 5.86 1825 - 1.07E+06 - - - -0.2392 - 2.399 0.393 - 186.5 1 2 0 -0.0004 12 0 0 0 1.08E+07 0.00E+00 - - - 5.347 1 221125_WJC_METTL3_EV_vs_WT_F06.08250.08250.2 8.47E-06 15/20 M.TTVHAITATQK.T "sp|P04406|G3P_HUMAN,tr|E7EUT5|E7EUT5_HUMAN" 2 1169.6404 1.31 78470 8250 2 1169.643266 585.8275 Glyceraldehyde-3-phosphate dehydrogenase OS=Homo sapiens OX=9606 GN=GAPDH PE=1 SV=3 8.44 1825.2 - 617502 - - - 2.4187 - 2.78 0.533 - 871.6 1 1 0 0.0028 11 0 0 0 9.03E+06 6.89E+06 - - - 5.7428 0.9999 221125_WJC_METTL3_EV_vs_WT_F06.08253.08253.2 4.04E-06 13/22 R.QVTQEEGQQLAR[166.11].Q "sp|P62070|RRAS2_HUMAN,tr|E9PK85|E9PK85_HUMAN" 2 1395.6982 0.83 78473 8253 2 1395.699296 698.8564 Ras-related protein R-Ras2 OS=Homo sapiens OX=9606 GN=RRAS2 PE=1 SV=1 4.53 1825.6 - 321798 - - - 0.8025 - 2.457 0.523 - 726 1 2 0 0.0011 12 0 0 0 7.14E+06 8.63E+06 - - - 5.2688 0.9969 221125_WJC_METTL3_EV_vs_WT_F06.08259.08259.3 0.272 Oct-40 R.SVSLVGEDER[166.11]K[136.11].M "sp|Q96GQ7|DDX27_HUMAN,tr|B7Z6D5|B7Z6D5_HUMAN" 2 1235.6477 1.44 78477 8259 3 1235.649632 412.8898 Probable ATP-dependent RNA helicase DDX27 OS=Homo sapiens OX=9606 GN=DDX27 PE=1 SV=2 4.68 1826.2 - 1.32E+06 - - - 1.6032 - 1.488 0.283 - 112.5 1 2 0 0.002 11 0 0 0 1.80E+07 1.25E+07 - - - 2.8237 0.9851 221125_WJC_METTL3_EV_vs_WT_F06.08261.08261.2 2.04E-06 13/20 M.TTVHAITATQK[136.11].T "sp|P04406|G3P_HUMAN,tr|E7EUT5|E7EUT5_HUMAN" 2 1177.6546 1.31 78479 8261 2 1177.656225 589.8346 Glyceraldehyde-3-phosphate dehydrogenase OS=Homo sapiens OX=9606 GN=GAPDH PE=1 SV=3 8.44 1826.4 - 886398 - - - 1.3484 - 2.162 0.444 - 547 1 1 0 0.0016 11 0 0 0 9.03E+06 6.89E+06 - - - 4.4057 0.9995 221125_WJC_METTL3_EV_vs_WT_F06.08262.08262.2 0.000468 16-Aug K.NQNDPLPGR.L "sp|O75534|CSDE1_HUMAN,tr|E9PLT0|E9PLT0_HUMAN" 2 1009.4941 0.65 78480 8262 2 1009.496084 505.7543 Cold shock domain-containing protein E1 OS=Homo sapiens OX=9606 GN=CSDE1 PE=1 SV=2 5.84 1826.5 - 858565 - - - 1.9584 - 1.723 0.435 - 252 1 2 0 0.002 9 0 0 0 9.65E+07 1.49E+08 - - - 3.8273 0.9997 221125_WJC_METTL3_EV_vs_WT_F06.08264.08264.3 0.000853 Sep-40 K.TNPEIQSTLRK.R sp|P31944|CASPE_HUMAN 1 1285.699 165.31 78482 8264 3 1285.699739 429.5736 Caspase-14 OS=Homo sapiens OX=9606 GN=CASP14 PE=1 SV=2 8.41 1826.7 - 585578 - - - 0.5639 - 1.855 0.358 - 135.5 1 2 0 0.0007 11 0 0 0 1.31E+07 7.95E+04 - - - 4.2864 0.9994 221125_WJC_METTL3_EV_vs_WT_F06.08266.08266.3 0.00556 Dec-48 R.QVLHGEALAGQAK[136.11].A sp|O95396|MOCS3_HUMAN 1 1328.7292 1.54 78484 8266 3 1328.730095 443.917 Adenylyltransferase and sulfurtransferase MOCS3 OS=Homo sapiens OX=9606 GN=MOCS3 PE=1 SV=1 6.75 1826.9 - 546893 - - - 0.6743 - 1.943 0.303 - 197 1 2 0 0.0009 13 0 0 0 2.16E+07 1.40E+07 - - - 3.7188 0.9258 221125_WJC_METTL3_EV_vs_WT_F06.08268.08268.2 0.00677 18-Nov T.TVHAITATQK.T "sp|P04406|G3P_HUMAN,tr|E7EUT5|E7EUT5_HUMAN" 2 1068.5928 1.06 78486 8268 2 1068.594285 535.3037 Glyceraldehyde-3-phosphate dehydrogenase OS=Homo sapiens OX=9606 GN=GAPDH PE=1 SV=3 8.44 1827.1 - 512952 - - - 1.429 - 1.579 0.304 - 326.7 1 1 0 0.0015 10 0 0 0 2.69E+06 2.53E+06 - - - 2.5609 0.9934 221125_WJC_METTL3_EV_vs_WT_F06.08274.08274.2 0.00213 18-Oct R.LKAEFQEEAK.R sp|P15924|DESP_HUMAN 1 1191.6136 5.34 78490 8274 2 1191.616555 596.8141 Desmoplakin OS=Homo sapiens OX=9606 GN=DSP PE=1 SV=3 4.79 1827.8 - 2.37E+06 - - - 2.5193 - 2.009 0.438 - 232.2 1 2 1 0.003 10 0 0 0 2.92E+07 5.47E+06 - - - 4.2224 0.9983 221125_WJC_METTL3_EV_vs_WT_F06.08275.08275.3 0.0118 Oct-48 R.QVLHGEALAGQAK.A sp|O95396|MOCS3_HUMAN 1 1320.715 1.54 78491 8275 3 1320.71785 441.2456 Adenylyltransferase and sulfurtransferase MOCS3 OS=Homo sapiens OX=9606 GN=MOCS3 PE=1 SV=1 6.75 1827.8 - 1.54E+06 - - - 2.1587 - 1.613 0.325 - 145.1 1 2 0 0.0029 13 0 0 0 2.16E+07 1.40E+07 - - - 3.4589 0.9993 221125_WJC_METTL3_EV_vs_WT_F06.08277.08277.2 0.000221 14-Sep R.NEC[160.03]FLQHK.D "sp|P02768|ALBU_HUMAN,tr|A0A087WWT3|A0A087WWT3_HUMAN,tr|H7C013|H7C013_HUMAN,tr|A0A0C4DGB6|A0A0C4DGB6_HUMAN" 4 1074.4917 0.47 78493 8277 2 1074.493801 538.2531 Albumin OS=Homo sapiens OX=9606 GN=ALB PE=1 SV=2 6.74 1828 - 874745 - - - 1.9888 - 1.657 0.4 - 322.4 1 2 0 0.0021 8 0 0 0 2.60E+07 5.52E+07 - - - 3.5178 0.9997 221125_WJC_METTL3_EV_vs_WT_F06.08278.08278.2 0.000572 13/22 R.QVTQEEGQQLAR.Q "sp|P62070|RRAS2_HUMAN,tr|E9PK85|E9PK85_HUMAN" 2 1385.6899 0.83 78494 8278 2 1385.692331 693.8522 Ras-related protein R-Ras2 OS=Homo sapiens OX=9606 GN=RRAS2 PE=1 SV=1 4.53 1828.1 - 848131 - - - 1.75 - 2.445 0.439 - 657.3 1 2 0 0.0024 12 0 0 0 7.14E+06 8.63E+06 - - - 4.6351 0.9964 221125_WJC_METTL3_EV_vs_WT_F06.08280.08280.2 4.34E-05 20-Nov K.NVAEALGHSPK.D sp|Q8IU81|I2BP1_HUMAN 1 1121.5829 1.2 78496 8280 2 1121.587566 561.7987 Interferon regulatory factor 2-binding protein 1 OS=Homo sapiens OX=9606 GN=IRF2BP1 PE=1 SV=1 6.75 1828.3 - 622104 - - - 4.1406 - 2.195 0.307 - 289 1 2 0 0.0046 11 0 0 0 1.19E+08 9.92E+07 - - - 3.4339 0.9695 221125_WJC_METTL3_EV_vs_WT_F06.08282.08282.2 0.0271 22-Aug K.AASQPTSLAPEK[136.11].L sp|Q96N66|MBOA7_HUMAN 1 1206.6336 0.001 78498 8282 2 1206.640572 604.3241 Lysophospholipid acyltransferase 7 OS=Homo sapiens OX=9606 GN=MBOAT7 PE=1 SV=2 6.05 1828.6 - 432202 - - - 5.8054 - 1.503 0.317 - 175.6 1 2 0 0.007 12 0 0 0 0.00E+00 6.64E+06 - - - 2.4523 0.9996 221125_WJC_METTL3_EV_vs_WT_F06.08287.08287.2 0.000218 20-Oct R.YPSSISSSPQK.D "sp|Q14157|UBP2L_HUMAN,tr|F8W726|F8W726_HUMAN" 2 1179.5772 2 78502 8287 2 1179.574908 590.7959 Ubiquitin-associated protein 2-like OS=Homo sapiens OX=9606 GN=UBAP2L PE=1 SV=2 8.59 1829.2 - 868572 - - - -1.9159 - 1.831 0.447 - 302 1 2 0 -0.0023 11 0 0 0 1.33E+08 6.62E+07 - - - 3.9781 0.9516 221125_WJC_METTL3_EV_vs_WT_F06.08288.08288.2 0.894 12-Jul K.NVPNWHR[166.11].D "sp|P62826|RAN_HUMAN,tr|B5MDF5|B5MDF5_HUMAN,tr|J3KQE5|J3KQE5_HUMAN,tr|B4DV51|B4DV51_HUMAN,tr|F5H018|F5H018_HUMAN" 5 931.4652 1.42 78503 8288 2 931.467993 466.7399 GTP-binding nuclear protein Ran OS=Homo sapiens OX=9606 GN=RAN PE=1 SV=3 9.76 1829.2 - 2.04E+06 - - - 2.9953 - 1.024 0.195 - 155.1 1 2 0 0.0028 7 0 0 0 8.41E+07 5.92E+07 - - - 0.5555 0.9997 221125_WJC_METTL3_EV_vs_WT_F06.08289.08289.2 0.000521 16-Sep K.QDSGHLDLR[166.11].N "sp|Q86U44|MTA70_HUMAN,tr|B4E349|B4E349_HUMAN,tr|F5H6D8|F5H6D8_HUMAN,tr|B4DTN4|B4DTN4_HUMAN" 4 1049.5129 0.01 78504 8289 2 1049.512622 525.7637 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 5.21 1829.3 - 1.49E+06 - - - -0.304 - 1.84 0.396 - 262.6 1 2 0 -0.0003 9 0 0 0 2.34E+06 1.62E+08 - - - 3.7298 0.9997 221125_WJC_METTL3_EV_vs_WT_F06.08290.08290.2 5.36E-06 20-Dec K.NVAEALGHSPK[136.11].D sp|Q8IU81|I2BP1_HUMAN 1 1129.5971 1.2 78505 8290 2 1129.600153 565.8058 Interferon regulatory factor 2-binding protein 1 OS=Homo sapiens OX=9606 GN=IRF2BP1 PE=1 SV=1 6.75 1829.4 - 1.04E+06 - - - 2.6833 - 2.374 0.535 - 385.4 1 2 0 0.003 11 0 0 0 1.19E+08 9.89E+07 - - - 5.3304 0.9997 221125_WJC_METTL3_EV_vs_WT_F06.08294.08294.2 7.07E-07 13/26 R.AVASQPDSVDAAER[166.11].A "sp|Q9NVE7|PANK4_HUMAN,tr|E9PHT6|E9PHT6_HUMAN,tr|H0YA26|H0YA26_HUMAN" 3 1424.6771 0.32 78509 8294 2 1424.680668 713.3458 4'-phosphopantetheine phosphatase OS=Homo sapiens OX=9606 GN=PANK4 PE=1 SV=1 4.03 1829.9 - 206002 - - - 2.5002 - 2.537 0.567 - 451.5 1 2 0 0.0036 14 0 0 0 6.25E+05 1.92E+06 - - - 5.564 0.9998 221125_WJC_METTL3_EV_vs_WT_F06.08298.08298.2 0.0011 20-Dec K.TVLDQQQTPSR[166.11].L "sp|P42704|LPPRC_HUMAN,tr|A0A804HI14|A0A804HI14_HUMAN,tr|A0A804HL40|A0A804HL40_HUMAN,tr|A0A804HKJ0|A0A804HKJ0_HUMAN,tr|A0A804HKR3|A0A804HKR3_HUMAN,tr|A0A804HIN4|A0A804HIN4_HUMAN,tr|A0A804HLG8|A0A804HLG8_HUMAN,tr|A0A804HJA1|A0A804HJA1_HUMAN,tr|A0A804HHY9|A0A804HHY9_HUMAN,tr|A0A804HI40|A0A804HI40_HUMAN,tr|A0A804HJZ1|A0A804HJZ1_HUMAN,tr|A0A804HIQ7|A0A804HIQ7_HUMAN,tr|A0A804HK30|A0A804HK30_HUMAN,tr|A0A804HKI2|A0A804HKI2_HUMAN,tr|A0A804HJI0|A0A804HJI0_HUMAN,tr|A0A804HKX6|A0A804HKX6_HUMAN,tr|A0A804HKK7|A0A804HKK7_HUMAN,tr|A0A804HIG4|A0A804HIG4_HUMAN" 18 1281.6552 0.73 78511 8298 2 1281.657802 641.8349 "Leucine-rich PPR motif-containing protein, mitochondrial OS=Homo sapiens OX=9606 GN=LRPPRC PE=1 SV=3" 5.5 1830.4 - 977806 - - - 1.992 - 2.217 0.534 - 453.4 1 2 0 0.0026 11 0 0 0 6.80E+07 9.29E+07 - - - 5.1381 0.9996 221125_WJC_METTL3_EV_vs_WT_F06.08302.08302.2 0.000244 20-Nov R.ADTQTYQPYNK.D sp|P84090|ERH_HUMAN 1 1327.6044 2.44 78515 8302 2 1327.606747 664.8095 Enhancer of rudimentary homolog OS=Homo sapiens OX=9606 GN=ERH PE=1 SV=1 5.88 1830.8 - 608549 - - - 1.734 - 2.098 0.419 - 414.3 1 2 0 0.0023 11 0 0 0 7.49E+09 3.07E+09 - - - 4.1395 0.9985 221125_WJC_METTL3_EV_vs_WT_F06.08303.08303.2 0.00423 18-Nov K.TVSVSEAIKK.N sp|P15924|DESP_HUMAN 1 1060.6128 6.56 78516 8303 2 1060.614918 531.3137 Desmoplakin OS=Homo sapiens OX=9606 GN=DSP PE=1 SV=3 8.26 1830.9 - 607220 - - - 1.9734 - 2.091 0.227 - 295.9 1 2 0 0.0021 10 0 0 0 5.14E+07 7.83E+06 - - - 2.7759 0.9995 221125_WJC_METTL3_EV_vs_WT_F06.08304.08304.2 6.13E-05 20-Nov R.ADTQTYQPYNK[136.11].D sp|P84090|ERH_HUMAN 1 1335.6186 2.44 78517 8304 2 1335.621904 668.8166 Enhancer of rudimentary homolog OS=Homo sapiens OX=9606 GN=ERH PE=1 SV=1 5.88 1831.1 - 528228 - - - 2.4401 - 1.948 0.482 - 399.2 1 2 0 0.0033 11 0 0 0 7.49E+09 3.07E+09 - - - 4.4039 1 221125_WJC_METTL3_EV_vs_WT_F06.08305.08305.2 1.37E-08 16/24 R.ASMQQQQQLASAR[166.11].N "sp|Q9Y3Y2|CHTOP_HUMAN,tr|A0A087X1B7|A0A087X1B7_HUMAN,tr|X6R700|X6R700_HUMAN" 3 1455.7128 1.64 78518 8305 2 1455.713682 728.8637 Chromatin target of PRMT1 protein OS=Homo sapiens OX=9606 GN=CHTOP PE=1 SV=2 9.79 1831.2 - 324152 - - - 0.6196 - 3.025 0.588 - 1205.9 1 2 0 0.0009 13 0 0 0 1.79E+08 1.09E+08 - - - 6.2246 1 221125_WJC_METTL3_EV_vs_WT_F06.08307.08307.2 9.31E-06 16/24 R.ASMQQQQQLASAR.N "sp|Q9Y3Y2|CHTOP_HUMAN,tr|A0A087X1B7|A0A087X1B7_HUMAN,tr|X6R700|X6R700_HUMAN" 3 1445.7045 1.64 78520 8307 2 1445.707944 723.8595 Chromatin target of PRMT1 protein OS=Homo sapiens OX=9606 GN=CHTOP PE=1 SV=2 9.79 1831.4 - 302633 - - - 2.3753 - 2.937 0.552 - 1234.5 1 2 0 0.0034 13 0 0 0 1.79E+08 1.09E+08 - - - 5.8821 0.9057 221125_WJC_METTL3_EV_vs_WT_F06.08311.08311.2 0.325 14-Jul K.HYLEAAAR[166.11].G "sp|Q32NC0|CR021_HUMAN,tr|A0A087X0E7|A0A087X0E7_HUMAN" 2 939.4802 1.96 78523 8311 2 939.482658 470.7474 UPF0711 protein C18orf21 OS=Homo sapiens OX=9606 GN=C18orf21 PE=1 SV=1 6.75 1831.9 - 2.58E+06 - - - 2.6323 - 1.326 0.023 - 261.5 2 2 0 0.0025 8 0 0 0 1.07E+08 5.48E+07 - - - -0.0734 1 221125_WJC_METTL3_EV_vs_WT_F06.08313.08313.2 3.65E-05 13/20 K.TVLDQQQTPSR.L "sp|P42704|LPPRC_HUMAN,tr|A0A804HI14|A0A804HI14_HUMAN,tr|A0A804HL40|A0A804HL40_HUMAN,tr|A0A804HKJ0|A0A804HKJ0_HUMAN,tr|A0A804HKR3|A0A804HKR3_HUMAN,tr|A0A804HIN4|A0A804HIN4_HUMAN,tr|A0A804HLG8|A0A804HLG8_HUMAN,tr|A0A804HJA1|A0A804HJA1_HUMAN,tr|A0A804HHY9|A0A804HHY9_HUMAN,tr|A0A804HI40|A0A804HI40_HUMAN,tr|A0A804HJZ1|A0A804HJZ1_HUMAN,tr|A0A804HIQ7|A0A804HIQ7_HUMAN,tr|A0A804HK30|A0A804HK30_HUMAN,tr|A0A804HKI2|A0A804HKI2_HUMAN,tr|A0A804HJI0|A0A804HJI0_HUMAN,tr|A0A804HKX6|A0A804HKX6_HUMAN,tr|A0A804HKK7|A0A804HKK7_HUMAN,tr|A0A804HIG4|A0A804HIG4_HUMAN" 18 1271.647 0.73 78525 8313 2 1271.65039 636.8308 "Leucine-rich PPR motif-containing protein, mitochondrial OS=Homo sapiens OX=9606 GN=LRPPRC PE=1 SV=3" 5.5 1832.1 - 1.03E+06 - - - 2.6823 - 2.348 0.597 - 560.9 1 2 0 0.0034 11 0 0 0 6.80E+07 9.29E+07 - - - 5.7585 0.9961 221125_WJC_METTL3_EV_vs_WT_F06.08314.08314.2 0.0292 16-Dec K.KAFTELQAK.V "sp|O60925|PFD1_HUMAN,tr|E5RGS4|E5RGS4_HUMAN" 2 1034.576 4.59 78526 8314 2 1034.57845 518.2953 Prefoldin subunit 1 OS=Homo sapiens OX=9606 GN=PFDN1 PE=1 SV=2 8.59 1832.2 - 849212 - - - 2.3237 - 1.914 0.161 - 482.1 1 2 0 0.0024 9 0 0 0 2.80E+07 6.10E+06 - - - 2.1075 0.903 221125_WJC_METTL3_EV_vs_WT_F06.08317.08317.3 0.142 Jun-48 K.YVANMHGDETVGR.E "sp|P14384|CBPM_HUMAN,tr|F8W111|F8W111_HUMAN,tr|F8VVI6|F8VVI6_HUMAN" 3 1447.6514 10.84 78529 8317 3 1447.653078 483.5577 Carboxypeptidase M OS=Homo sapiens OX=9606 GN=CPM PE=1 SV=2 5.32 1832.5 - 236833 - - - 1.1508 - 1.231 0.163 - 31.7 6 2 0 0.0017 13 0 0 0 1.79E+06 1.65E+05 - - - 0.5602 0.9982 221125_WJC_METTL3_EV_vs_WT_F06.08318.08318.2 0.000942 18-Jul K.AFVNC[160.03]DENSR.L sp|P01833|PIGR_HUMAN 1 1210.5037 999 78530 8318 2 1210.508094 606.2591 Polymeric immunoglobulin receptor OS=Homo sapiens OX=9606 GN=PIGR PE=1 SV=4 4.37 1832.7 - 193178 - - - 3.6415 - 1.54 0.487 - 203.5 1 2 0 0.0044 10 0 0 0 1.96E+07 0.00E+00 - - - 3.8418 0.9993 221125_WJC_METTL3_EV_vs_WT_F06.08324.08324.3 0.0224 Oct-44 K.R[166.11]AGELTEDEVER[166.11].V sp|P62269|RS18_HUMAN 1 1422.6854 0.86 78534 8324 3 1422.688852 475.2357 40S ribosomal protein S18 OS=Homo sapiens OX=9606 GN=RPS18 PE=1 SV=3 4.25 1833.3 - 831098 - - - 2.4433 - 1.792 0.373 - 167.3 1 2 0 0.0035 12 0 0 0 8.43E+06 9.78E+06 - - - 4.3145 0.9995 221125_WJC_METTL3_EV_vs_WT_F06.08325.08325.2 0.000187 20-Oct K.SEYIETASGNK.V "sp|Q9BTE1|DCTN5_HUMAN,tr|H3BUD2|H3BUD2_HUMAN,tr|H3BR94|H3BR94_HUMAN,tr|H3BS05|H3BS05_HUMAN" 4 1197.5513 2.14 78535 8325 2 1197.55408 599.7829 Dynactin subunit 5 OS=Homo sapiens OX=9606 GN=DCTN5 PE=1 SV=1 4.53 1833.4 - 646190 - - - 2.2822 - 1.97 0.462 - 336.3 1 2 0 0.0027 11 0 0 0 3.91E+07 1.83E+07 - - - 4.2867 0.9998 221125_WJC_METTL3_EV_vs_WT_F06.08326.08326.2 1.56E-05 20-Oct K.SEYIETASGNK[136.11].V "sp|Q9BTE1|DCTN5_HUMAN,tr|H3BUD2|H3BUD2_HUMAN,tr|H3BR94|H3BR94_HUMAN,tr|H3BS05|H3BS05_HUMAN" 4 1205.5655 2.14 78536 8326 2 1205.567367 603.79 Dynactin subunit 5 OS=Homo sapiens OX=9606 GN=DCTN5 PE=1 SV=1 4.53 1833.6 - 531356 - - - 1.5097 - 2.206 0.498 - 345 1 2 0 0.0018 11 0 0 0 3.91E+07 1.83E+07 - - - 4.859 0.9386 221125_WJC_METTL3_EV_vs_WT_F06.08332.08332.3 0.1 Sep-36 R.LK[136.11]QIEEQTIK[136.11].A "sp|P35241|RADI_HUMAN,tr|A0A2R8Y5S7|A0A2R8Y5S7_HUMAN,tr|A0A2R8Y7M3|A0A2R8Y7M3_HUMAN" 3 1244.7311 0.28 78540 8332 3 1244.73287 415.9176 Radixin OS=Homo sapiens OX=9606 GN=RDX PE=1 SV=1 6.14 1834.3 - 1.11E+06 - - - 1.4196 - 1.597 0.169 - 105.8 1 2 1 0.0018 10 0 0 0 3.49E+06 1.23E+07 - - - 1.7908 0.9996 221125_WJC_METTL3_EV_vs_WT_F06.08333.08333.2 0.00928 18-Oct K.QNESTIVEPK.Q "sp|Q6KC79|NIPBL_HUMAN,tr|A0A590UJS4|A0A590UJS4_HUMAN" 2 1143.5772 2.47 78541 8333 2 1143.578707 572.7959 Nipped-B-like protein OS=Homo sapiens OX=9606 GN=NIPBL PE=1 SV=2 4.53 1834.5 - 876095 - - - 1.3458 - 1.739 0.42 - 306.2 1 2 0 0.0015 10 0 0 0 2.27E+07 9.21E+06 - - - 3.6871 0.9999 221125_WJC_METTL3_EV_vs_WT_F06.08334.08334.3 0.000169 14/40 R.K[136.11]YPEAAAC[160.03]YGR[166.11].A "sp|Q9UNE7|CHIP_HUMAN,tr|H3BS86|H3BS86_HUMAN" 2 1302.6146 0.5 78542 8334 3 1302.61684 435.2121 E3 ubiquitin-protein ligase CHIP OS=Homo sapiens OX=9606 GN=STUB1 PE=1 SV=2 8.18 1834.5 - 1.82E+06 - - - 1.7373 - 2.355 0.429 - 466.2 1 2 0 0.0023 11 0 0 0 1.23E+07 2.45E+07 - - - 5.7556 1 221125_WJC_METTL3_EV_vs_WT_F06.08336.08336.2 4.14E-07 16-Nov R.NGYDYGQC[160.03]R[166.11].L "sp|Q13242|SRSF9_HUMAN,tr|S4R3G0|S4R3G0_HUMAN" 2 1141.4486 1.51 78544 8336 2 1141.451462 571.7316 Serine\arginine-rich splicing factor 9 OS=Homo sapiens OX=9606 GN=SRSF9 PE=1 SV=1 5.83 1834.7 - 918627 - - - 2.4837 - 2.185 0.653 - 508.8 1 2 0 0.0028 9 0 0 0 2.15E+07 1.43E+07 - - - 6.1244 0.9998 221125_WJC_METTL3_EV_vs_WT_F06.08339.08339.2 0.00408 20-Oct R.K[136.11]YPEAAAC[160.03]YGR[166.11].A "sp|Q9UNE7|CHIP_HUMAN,tr|H3BS86|H3BS86_HUMAN" 2 1302.6146 0.07 78547 8339 2 1302.615436 652.3146 E3 ubiquitin-protein ligase CHIP OS=Homo sapiens OX=9606 GN=STUB1 PE=1 SV=2 8.18 1835.1 - 346048 - - - 0.6594 - 2.035 0.418 - 324.4 1 2 0 0.0009 11 0 0 0 2.77E+05 3.98E+06 - - - 4.0501 1 221125_WJC_METTL3_EV_vs_WT_F06.08346.08346.3 3.33E-06 14/48 R.ASMQQQQQLASAR[166.11].N "sp|Q9Y3Y2|CHTOP_HUMAN,tr|A0A087X1B7|A0A087X1B7_HUMAN,tr|X6R700|X6R700_HUMAN" 3 1455.7128 1.67 78552 8346 3 1455.712618 486.2449 Chromatin target of PRMT1 protein OS=Homo sapiens OX=9606 GN=CHTOP PE=1 SV=2 9.79 1836 - 622085 - - - -0.1113 - 2.682 0.502 - 311.4 1 2 0 -0.0002 13 0 0 0 1.69E+07 1.01E+07 - - - 6.8116 0.9998 221125_WJC_METTL3_EV_vs_WT_F06.08348.08348.2 0.000106 16-Nov R.IHAEFVQQK[136.11].N sp|P19474|RO52_HUMAN 1 1106.5964 1.72 78554 8348 2 1106.597818 554.3055 E3 ubiquitin-protein ligase TRIM21 OS=Homo sapiens OX=9606 GN=TRIM21 PE=1 SV=1 6.75 1836.2 - 996656 - - - 1.2868 - 2.04 0.469 - 520.5 1 2 0 0.0014 9 0 0 0 9.03E+07 5.25E+07 - - - 4.5672 1 221125_WJC_METTL3_EV_vs_WT_F06.08349.08349.2 6.98E-07 18/22 R.KAEAAVVAVAEK.R "sp|Q8IZQ5|SELH_HUMAN,tr|A0A087WYP2|A0A087WYP2_HUMAN" 2 1184.6765 1.1 78555 8349 2 1184.676449 593.3455 Selenoprotein H OS=Homo sapiens OX=9606 GN=SELENOH PE=1 SV=2 6.14 1836.3 - 924118 - - - -0.0329 - 3.252 0.577 - 1058.5 1 2 0 0 12 0 0 0 1.46E+07 1.33E+07 - - - 6.4056 0.9997 221125_WJC_METTL3_EV_vs_WT_F06.08350.08350.3 0.000313 Dec-44 R.KAEAAVVAVAEK.R "sp|Q8IZQ5|SELH_HUMAN,tr|A0A087WYP2|A0A087WYP2_HUMAN" 2 1184.6765 1.41 78556 8350 3 1184.676343 395.8994 Selenoprotein H OS=Homo sapiens OX=9606 GN=SELENOH PE=1 SV=2 6.14 1836.4 - 790346 - - - -0.1224 - 1.979 0.33 - 213.6 1 2 0 -0.0001 12 0 0 0 1.70E+07 1.20E+07 - - - 4.1112 0.9762 221125_WJC_METTL3_EV_vs_WT_F06.08351.08351.2 0.0385 18-Nov K.SPSVSLSQSK[136.11].E "sp|Q5VT06|CE350_HUMAN,tr|H0Y6Q4|H0Y6Q4_HUMAN" 2 1026.5437 2.03 78557 8351 2 1026.549738 514.2791 Centrosome-associated protein 350 OS=Homo sapiens OX=9606 GN=CEP350 PE=1 SV=1 8.47 1836.5 - 550176 - - - 5.8926 - 1.962 0.246 - 459.1 1 2 0 0.006 10 0 0 0 2.57E+07 1.26E+07 - - - 2.7373 0.9996 221125_WJC_METTL3_EV_vs_WT_F06.08352.08352.2 3.82E-05 14/22 R.QLEGVDTQGTNR.V sp|O15047|SET1A_HUMAN 1 1316.6321 1.74 78558 8352 2 1316.635485 659.3233 Histone-lysine N-methyltransferase SETD1A OS=Homo sapiens OX=9606 GN=SETD1A PE=1 SV=3 4.37 1836.6 - 393601 - - - 2.6036 - 2.39 0.502 - 851.3 1 2 0 0.0034 12 0 0 0 8.14E+06 4.68E+06 - - - 5.0402 0.9993 221125_WJC_METTL3_EV_vs_WT_F06.08359.08359.3 0.00346 Dec-36 K.QQLVASHLEK.L "sp|Q13561|DCTN2_HUMAN,tr|H0YI98|H0YI98_HUMAN,tr|A8K8J9|A8K8J9_HUMAN,tr|F8W1I6|F8W1I6_HUMAN,tr|A0A7I2V4H4|A0A7I2V4H4_HUMAN,tr|A0A7I2V390|A0A7I2V390_HUMAN,tr|A0A7I2V4Y9|A0A7I2V4Y9_HUMAN,tr|F8VW18|F8VW18_HUMAN" 8 1151.6299 3.45 78563 8359 3 1151.629976 384.8839 Dynactin subunit 2 OS=Homo sapiens OX=9606 GN=DCTN2 PE=1 SV=4 6.75 1837.4 - 3.30E+06 - - - 0.0903 - 2.01 0.265 - 260.1 1 2 0 0.0001 10 0 0 0 2.73E+08 7.92E+07 - - - 3.5333 0.9936 221125_WJC_METTL3_EV_vs_WT_F06.08360.08360.3 0.111 Jul-40 R.ADTQTYQPYNK.D sp|P84090|ERH_HUMAN 1 1327.6044 3.35 78564 8360 3 1327.608648 443.5421 Enhancer of rudimentary homolog OS=Homo sapiens OX=9606 GN=ERH PE=1 SV=1 5.88 1837.5 - 2.09E+06 - - - 3.1659 - 1.446 0.309 - 52 1 2 0 0.0042 11 0 0 0 1.38E+08 4.12E+07 - - - 3.0316 0.9999 221125_WJC_METTL3_EV_vs_WT_F06.08361.08361.3 0.000283 Dec-48 R.LEHEEGAPC[160.03]TAIR.E "sp|Q00537|CDK17_HUMAN,sp|Q07002|CDK18_HUMAN,sp|Q00536|CDK16_HUMAN,tr|A0A0A0MSJ6|A0A0A0MSJ6_HUMAN,tr|F5H6Z0|F5H6Z0_HUMAN,tr|E5RGN0|E5RGN0_HUMAN,tr|A0A087WZU2|A0A087WZU2_HUMAN" 7 1481.6933 1.1 78565 8361 3 1481.695031 494.905 Cyclin-dependent kinase 17 OS=Homo sapiens OX=9606 GN=CDK17 PE=1 SV=2 4.75 1837.6 - 1.83E+06 - - - 1.1838 - 2.124 0.427 - 278 1 2 0 0.0018 13 0 0 0 4.24E+07 3.85E+07 - - - 5.3426 0.9996 221125_WJC_METTL3_EV_vs_WT_F06.08363.08363.3 0.00109 13/36 K.QQLVASHLEK[136.11].L "sp|Q13561|DCTN2_HUMAN,tr|H0YI98|H0YI98_HUMAN,tr|A8K8J9|A8K8J9_HUMAN,tr|F8W1I6|F8W1I6_HUMAN,tr|A0A7I2V4H4|A0A7I2V4H4_HUMAN,tr|A0A7I2V390|A0A7I2V390_HUMAN,tr|A0A7I2V4Y9|A0A7I2V4Y9_HUMAN,tr|F8VW18|F8VW18_HUMAN" 8 1159.6441 3.45 78567 8363 3 1159.644785 387.5553 Dynactin subunit 2 OS=Homo sapiens OX=9606 GN=DCTN2 PE=1 SV=4 6.75 1837.7 - 1.25E+06 - - - 0.6148 - 2.104 0.298 - 264.4 1 2 0 0.0007 10 0 0 0 2.73E+08 7.92E+07 - - - 4.0345 0.998 221125_WJC_METTL3_EV_vs_WT_F06.08364.08364.2 0.493 18-Sep K.TVSVSEAIK[136.11]K[136.11].N sp|P15924|DESP_HUMAN 1 1076.6412 6.56 78568 8364 2 1076.642433 539.3279 Desmoplakin OS=Homo sapiens OX=9606 GN=DSP PE=1 SV=3 8.26 1837.9 - 557811 - - - 1.122 - 1.533 0.247 - 187.7 1 2 0 0.0012 10 0 0 0 5.14E+07 7.83E+06 - - - 2.0575 0.981 221125_WJC_METTL3_EV_vs_WT_F06.08373.08373.2 0.421 14-Aug K.TIQVPQQK.A "sp|Q9BY77|PDIP3_HUMAN,tr|F8WCX5|F8WCX5_HUMAN" 2 940.5342 1.38 78574 8373 2 940.532988 471.2744 Polymerase delta-interacting protein 3 OS=Homo sapiens OX=9606 GN=POLDIP3 PE=1 SV=2 8.41 1838.9 - 3.30E+06 - - - -1.2684 - 1.082 0.151 - 193.1 1 2 0 -0.0012 8 0 0 0 1.74E+08 1.26E+08 - - - 0.3936 0.9993 221125_WJC_METTL3_EV_vs_WT_F06.08374.08374.2 0.0676 14-Sep K.TIQVPQQK[136.11].A "sp|Q9BY77|PDIP3_HUMAN,tr|F8WCX5|F8WCX5_HUMAN" 2 948.5484 1.38 78575 8374 2 948.547831 475.2815 Polymerase delta-interacting protein 3 OS=Homo sapiens OX=9606 GN=POLDIP3 PE=1 SV=2 8.41 1839 - 2.55E+06 - - - -0.5798 - 1.638 0.296 - 257.7 1 2 0 -0.0006 8 0 0 0 1.74E+08 1.26E+08 - - - 2.7154 0.9996 221125_WJC_METTL3_EV_vs_WT_F06.08375.08375.2 0.0199 18-Nov K.QQLVASHLEK.L "sp|Q13561|DCTN2_HUMAN,tr|H0YI98|H0YI98_HUMAN,tr|A8K8J9|A8K8J9_HUMAN,tr|F8W1I6|F8W1I6_HUMAN,tr|A0A7I2V4H4|A0A7I2V4H4_HUMAN,tr|A0A7I2V390|A0A7I2V390_HUMAN,tr|A0A7I2V4Y9|A0A7I2V4Y9_HUMAN,tr|F8VW18|F8VW18_HUMAN" 8 1151.6299 3.29 78576 8375 2 1151.630494 576.8222 Dynactin subunit 2 OS=Homo sapiens OX=9606 GN=DCTN2 PE=1 SV=4 6.75 1839.1 - 1.93E+06 - - - 0.5401 - 1.954 0.326 - 594.5 1 2 0 0.0006 10 0 0 0 6.56E+07 1.99E+07 - - - 3.3185 0.9991 221125_WJC_METTL3_EV_vs_WT_F06.08379.08379.3 0.000584 14/48 K.SGGGLHSVAEGVR[166.11].L sp|Q9NWK9|BCD1_HUMAN 1 1234.6294 1.89 78580 8379 3 1234.629384 412.5504 Box C\D snoRNA protein 1 OS=Homo sapiens OX=9606 GN=ZNHIT6 PE=1 SV=1 6.47 1839.4 - 1.11E+06 - - - 0.013 - 2.218 0.244 - 197.4 1 2 0 0 13 0 0 0 1.70E+07 8.99E+06 - - - 3.4202 0.999 221125_WJC_METTL3_EV_vs_WT_F06.08380.08380.2 0.0629 18-Oct K.QQLVASHLEK[136.11].L "sp|Q13561|DCTN2_HUMAN,tr|H0YI98|H0YI98_HUMAN,tr|A8K8J9|A8K8J9_HUMAN,tr|F8W1I6|F8W1I6_HUMAN,tr|A0A7I2V4H4|A0A7I2V4H4_HUMAN,tr|A0A7I2V390|A0A7I2V390_HUMAN,tr|A0A7I2V4Y9|A0A7I2V4Y9_HUMAN,tr|F8VW18|F8VW18_HUMAN" 8 1159.6441 3.29 78581 8380 2 1159.646311 580.8293 Dynactin subunit 2 OS=Homo sapiens OX=9606 GN=DCTN2 PE=1 SV=4 6.75 1839.6 - 704140 - - - 1.9308 - 1.772 0.334 - 384.3 1 2 0 0.0022 10 0 0 0 6.56E+07 1.99E+07 - - - 3.1042 0.9998 221125_WJC_METTL3_EV_vs_WT_F06.08384.08384.2 7.70E-05 13/26 R.AGASIPSSGAASPR.G sp|Q9P270|SLAI2_HUMAN 1 1227.6208 1.07 78584 8384 2 1227.621751 614.8177 SLAIN motif-containing protein 2 OS=Homo sapiens OX=9606 GN=SLAIN2 PE=1 SV=2 9.79 1840 - 2.02E+06 - - - 0.804 - 2.399 0.453 - 303.4 1 2 0 0.001 14 0 0 0 2.20E+07 2.06E+07 - - - 4.5824 1 221125_WJC_METTL3_EV_vs_WT_F06.08388.08388.2 3.52E-08 13/22 K.VGGTSDVEVNEK.K "sp|P10809|CH60_HUMAN,tr|A0A7I2V2X6|A0A7I2V2X6_HUMAN,tr|A0A7I2YQK6|A0A7I2YQK6_HUMAN,tr|A0A7I2V599|A0A7I2V599_HUMAN" 4 1232.5885 1.09 78588 8388 2 1232.588358 617.3015 "60 kDa heat shock protein, mitochondrial OS=Homo sapiens OX=9606 GN=HSPD1 PE=1 SV=2" 4.14 1840.5 - 871488 - - - -0.0836 - 2.843 0.593 - 750.8 1 2 0 -0.0001 12 0 0 0 4.29E+07 3.95E+07 - - - 6.1701 0.9721 221125_WJC_METTL3_EV_vs_WT_F06.08390.08390.2 1.49 16-Jul K.FKPNSVTYR.T "sp|Q7L2E3|DHX30_HUMAN,tr|H7BXY3|H7BXY3_HUMAN" 2 1110.5822 0.2 78590 8390 2 1110.5818 556.2984 ATP-dependent RNA helicase DHX30 OS=Homo sapiens OX=9606 GN=DHX30 PE=1 SV=1 9.99 1840.7 - 1.08E+06 - - - -0.3548 - 1.232 0.059 - 106.8 2 2 0 -0.0004 9 0 0 0 3.14E+06 1.57E+07 - - - -0.0542 0.9999 221125_WJC_METTL3_EV_vs_WT_F06.08393.08393.3 6.81E-06 13/36 K.SLHQLQVENR.R "sp|P55197|AF10_HUMAN,tr|Q5JT35|Q5JT35_HUMAN" 2 1222.6418 2.96 78591 8393 3 1222.639921 408.5546 Protein AF-10 OS=Homo sapiens OX=9606 GN=MLLT10 PE=1 SV=2 6.47 1841.1 - 4.37E+06 - - - -1.5646 - 2.357 0.439 - 360.8 1 2 0 -0.0019 10 0 0 0 7.64E+07 2.58E+07 - - - 5.9378 0.9988 221125_WJC_METTL3_EV_vs_WT_F06.08397.08397.3 0.000897 Oct-36 K.SLHQLQVENR[166.11].R "sp|P55197|AF10_HUMAN,tr|Q5JT35|Q5JT35_HUMAN" 2 1232.6501 3.07 78595 8397 3 1232.646814 411.8906 Protein AF-10 OS=Homo sapiens OX=9606 GN=MLLT10 PE=1 SV=2 6.47 1841.4 - 1.40E+06 - - - -2.669 - 1.799 0.335 - 183.6 1 2 0 -0.0033 10 0 0 0 7.90E+07 2.58E+07 - - - 3.989 0.9998 221125_WJC_METTL3_EV_vs_WT_F06.08400.08400.2 0.000187 20-Nov R.VHTSPNAIIGK.F sp|P22735|TGM1_HUMAN 1 1135.635 999 78598 8400 2 1135.63611 568.8248 Protein-glutamine gamma-glutamyltransferase K OS=Homo sapiens OX=9606 GN=TGM1 PE=1 SV=4 8.73 1841.7 - 896250 - - - 1.0153 - 2.108 0.447 - 418.4 1 2 0 0.0012 11 0 0 0 3.12E+07 0.00E+00 - - - 4.3596 0.9997 221125_WJC_METTL3_EV_vs_WT_F06.08401.08401.2 0.000725 16-Aug R.NIHSSDWPK[136.11].F "sp|Q9Y224|RTRAF_HUMAN,tr|G3V4C6|G3V4C6_HUMAN,tr|G3V4E7|G3V4E7_HUMAN" 3 1090.5287 1.05 78599 8401 2 1090.527394 546.2716 "RNA transcription, translation and transport factor protein OS=Homo sapiens OX=9606 GN=RTRAF PE=1 SV=1" 6.74 1841.9 - 891112 - - - -1.2049 - 1.655 0.439 - 239.8 1 2 0 -0.0013 9 0 0 0 6.11E+07 5.84E+07 - - - 3.7406 0.9838 221125_WJC_METTL3_EV_vs_WT_F06.08409.08409.2 0.0251 14-Sep K.HQLEEELR[166.11].Q sp|Q9ULW0|TPX2_HUMAN 1 1062.5333 0.8 78604 8409 2 1062.526926 532.2739 Targeting protein for Xklp2 OS=Homo sapiens OX=9606 GN=TPX2 PE=1 SV=2 4.75 1842.8 - 984733 - - - -6.0393 - 1.682 0.354 - 249 1 2 0 -0.0064 8 0 0 0 9.31E+06 1.16E+07 - - - 3.2219 0.9997 221125_WJC_METTL3_EV_vs_WT_F06.08410.08410.2 0.00292 18-Dec K.SLHQLQVENR.R "sp|P55197|AF10_HUMAN,tr|Q5JT35|Q5JT35_HUMAN" 2 1222.6418 5.28 78605 8410 2 1222.641397 612.3282 Protein AF-10 OS=Homo sapiens OX=9606 GN=MLLT10 PE=1 SV=2 6.47 1842.9 - 882082 - - - -0.3574 - 1.957 0.376 - 578.8 1 2 0 -0.0004 10 0 0 0 1.15E+07 2.18E+06 - - - 3.6921 0.9923 221125_WJC_METTL3_EV_vs_WT_F06.08413.08413.2 6.18E-05 24-Dec A.VANANSTPPPYER.T sp|Q96PK6|RBM14_HUMAN 1 1414.6841 2.45 78608 8413 2 1414.681963 708.3493 RNA-binding protein 14 OS=Homo sapiens OX=9606 GN=RBM14 PE=1 SV=2 5.97 1843.3 - 367319 - - - -1.5056 - 2.71 0.55 - 378.3 1 1 0 -0.0021 13 0 0 0 4.06E+07 1.66E+07 - - - 5.6613 0.9999 221125_WJC_METTL3_EV_vs_WT_F06.08416.08416.3 0.045 Dec-40 R.LQVQNGPIGHR.G sp|P57105|SYJ2B_HUMAN 1 1217.6629 2.18 78609 8416 3 1217.661384 406.8949 Synaptojanin-2-binding protein OS=Homo sapiens OX=9606 GN=SYNJ2BP PE=1 SV=2 9.76 1843.7 - 6.49E+06 - - - -1.2475 - 2.848 0.395 - 221.3 1 2 0 -0.0015 11 0 0 0 1.31E+08 6.03E+07 - - - 5.9167 0.9996 221125_WJC_METTL3_EV_vs_WT_F06.08419.08419.2 8.29E-05 16-Sep R.MHVQLSTSR.L "sp|Q9BWF3|RBM4_HUMAN,sp|Q9BQ04|RBM4B_HUMAN,tr|E9PB51|E9PB51_HUMAN" 3 1057.5339 1.24 78612 8419 2 1057.531567 529.7742 RNA-binding protein 4 OS=Homo sapiens OX=9606 GN=RBM4 PE=1 SV=1 9.52 1843.9 - 2.47E+06 - - - -2.1711 - 1.636 0.508 - 249 1 2 0 -0.0023 9 0 0 0 9.53E+08 7.67E+08 - - - 4.2165 0.9997 221125_WJC_METTL3_EV_vs_WT_F06.08420.08420.2 0.00196 20-Aug R.YSLSGGGTSSH.- "sp|Q9Y6E0|STK24_HUMAN,tr|B4DR80|B4DR80_HUMAN,tr|Q5JV98|Q5JV98_HUMAN" 3 1051.4571 - 78613 8420 2 1051.456713 526.7358 Serine\threonine-protein kinase 24 OS=Homo sapiens OX=9606 GN=STK24 PE=1 SV=1 6.74 1843.9 - 2.32E+06 - - - -0.3234 - 1.674 0.433 - 153.6 1 2 0 -0.0003 11 0 0 0 - - - - - 3.6328 0.9974 221125_WJC_METTL3_EV_vs_WT_F06.08423.08423.2 0.0491 20-Nov R.SGC[160.03]ENPPIVSK[136.11].D "sp|O94842|TOX4_HUMAN,tr|A0A669KB71|A0A669KB71_HUMAN" 2 1194.5794 0.61 78616 8423 2 1194.57826 598.297 TOX high mobility group box family member 4 OS=Homo sapiens OX=9606 GN=TOX4 PE=1 SV=1 5.72 1844.3 - 1.00E+06 - - - -0.9736 - 1.231 0.285 - 207.1 1 2 0 -0.0012 11 0 0 0 1.73E+07 2.84E+07 - - - 1.7079 0.9946 221125_WJC_METTL3_EV_vs_WT_F06.08424.08424.2 0.032 22-May K.NIC[160.03]EGGEEMDNK.F "sp|P24928|RPB1_HUMAN,tr|A0A6Q8PGB0|A0A6Q8PGB0_HUMAN" 2 1394.5442 999 78617 8424 2 1394.540882 698.2794 DNA-directed RNA polymerase II subunit RPB1 OS=Homo sapiens OX=9606 GN=POLR2A PE=1 SV=2 4 1844.4 - 874233 - - - -2.4008 - 1.117 0.34 - 52.6 1 2 0 -0.0033 12 0 0 0 1.10E+07 0.00E+00 - - - 1.8423 0.9934 221125_WJC_METTL3_EV_vs_WT_F06.08428.08428.2 0.00982 20-Nov N.LQQSISDAEQR.G sp|P04264|K2C1_HUMAN 1 1273.6262 372.26 78619 8428 2 1273.626461 637.8204 "Keratin, type II cytoskeletal 1 OS=Homo sapiens OX=9606 GN=KRT1 PE=1 SV=6" 4.37 1844.9 - 1.67E+06 - - - 0.1712 - 2.434 0.488 - 622.8 1 1 0 0.0002 11 0 0 0 7.23E+07 1.94E+05 - - - 5.0517 0.9991 221125_WJC_METTL3_EV_vs_WT_F06.08429.08429.3 0.000611 13/36 K.LLEQYKEESK.K "sp|Q00839|HNRPU_HUMAN,tr|A0A1W2PQL0|A0A1W2PQL0_HUMAN,tr|A0A1W2PPL4|A0A1W2PPL4_HUMAN,tr|Q5RI18|Q5RI18_HUMAN,tr|A0A1W2PP35|A0A1W2PP35_HUMAN,tr|A0A1W2PPS1|A0A1W2PPS1_HUMAN,tr|A0A1W2PPH7|A0A1W2PPH7_HUMAN,tr|A0A1W2PQD4|A0A1W2PQD4_HUMAN,tr|A0A1W2PP34|A0A1W2PP34_HUMAN,tr|A0A1X7SBS1|A0A1X7SBS1_HUMAN" 10 1265.6503 0.96 78620 8429 3 1265.64804 422.8907 Heterogeneous nuclear ribonucleoprotein U OS=Homo sapiens OX=9606 GN=HNRNPU PE=1 SV=6 4.79 1845 - 2.56E+06 - - - -1.8117 - 2.459 0.341 - 336.2 1 2 1 -0.0023 10 0 0 0 4.40E+09 4.57E+09 - - - 4.9689 1 221125_WJC_METTL3_EV_vs_WT_F06.08431.08431.2 8.45E-08 14/20 R.TDENGLC[160.03]PAC[160.03]R.K sp|O95628|CNOT4_HUMAN 1 1291.5285 2.38 78622 8431 2 1291.530874 646.7715 CCR4-NOT transcription complex subunit 4 OS=Homo sapiens OX=9606 GN=CNOT4 PE=1 SV=3 4.37 1845.2 - 937478 - - - 1.8226 - 2.85 0.639 - 845.4 1 2 0 0.0024 11 0 0 0 4.82E+07 2.03E+07 - - - 6.5932 1 221125_WJC_METTL3_EV_vs_WT_F06.08438.08438.2 0.000298 14/22 K.IETNENNLESAK.G sp|Q07065|CKAP4_HUMAN 1 1360.647 1.73 78627 8438 2 1360.64455 681.3308 Cytoskeleton-associated protein 4 OS=Homo sapiens OX=9606 GN=CKAP4 PE=1 SV=2 4.25 1845.9 - 1.84E+06 - - - -1.8285 - 2.783 0.603 - 734 1 2 0 -0.0025 12 0 0 0 1.50E+08 8.64E+07 - - - 6.1871 0.9988 221125_WJC_METTL3_EV_vs_WT_F06.08448.08448.2 2.17E-05 18-Dec K.LLEQYKEESK.K "sp|Q00839|HNRPU_HUMAN,tr|A0A1W2PQL0|A0A1W2PQL0_HUMAN,tr|A0A1W2PPL4|A0A1W2PPL4_HUMAN,tr|Q5RI18|Q5RI18_HUMAN,tr|A0A1W2PP35|A0A1W2PP35_HUMAN,tr|A0A1W2PPS1|A0A1W2PPS1_HUMAN,tr|A0A1W2PPH7|A0A1W2PPH7_HUMAN,tr|A0A1W2PQD4|A0A1W2PQD4_HUMAN,tr|A0A1W2PP34|A0A1W2PP34_HUMAN,tr|A0A1X7SBS1|A0A1X7SBS1_HUMAN" 10 1265.6503 1 78634 8448 2 1265.649211 633.8324 Heterogeneous nuclear ribonucleoprotein U OS=Homo sapiens OX=9606 GN=HNRNPU PE=1 SV=6 4.79 1847 - 3.72E+06 - - - -0.8865 - 2.405 0.519 - 533.8 1 2 1 -0.0011 10 0 0 0 1.05E+09 1.05E+09 - - - 5.3235 1 221125_WJC_METTL3_EV_vs_WT_F06.08449.08449.2 4.97E-08 15/24 R.FDDGAGGDNEVQR[166.11].T "sp|P35998|PRS7_HUMAN,tr|C9JX88|C9JX88_HUMAN" 2 1388.5832 0.69 78635 8449 2 1388.58299 695.2989 26S proteasome regulatory subunit 7 OS=Homo sapiens OX=9606 GN=PSMC2 PE=1 SV=3 3.84 1847.1 - 2.28E+06 - - - -0.1556 - 3.063 0.723 - 660.8 1 2 0 -0.0002 13 0 0 0 5.33E+07 7.71E+07 - - - 7.254 0.9997 221125_WJC_METTL3_EV_vs_WT_F06.08453.08453.2 0.00563 16-Oct K.HLTYENVER.W "sp|Q15907|RB11B_HUMAN,sp|P62491|RB11A_HUMAN,tr|H3BMH2|H3BMH2_HUMAN,tr|H3BSC1|H3BSC1_HUMAN" 4 1159.5622 1.38 78639 8453 2 1159.56094 580.7884 Ras-related protein Rab-11B OS=Homo sapiens OX=9606 GN=RAB11B PE=1 SV=4 5.4 1847.5 - 538104 - - - -1.0745 - 1.841 0.409 - 343.3 1 2 0 -0.0012 9 0 0 0 2.97E+08 2.16E+08 - - - 3.8271 0.999 221125_WJC_METTL3_EV_vs_WT_F06.08459.08459.2 0.00859 18-Aug K.MVQFEENGR[166.11]K[136.11].E "sp|P49368|TCPG_HUMAN,tr|Q5SZW8|Q5SZW8_HUMAN,tr|E9PRC8|E9PRC8_HUMAN,tr|B4DUR8|B4DUR8_HUMAN,tr|E9PQ35|E9PQ35_HUMAN,tr|Q5SZX6|Q5SZX6_HUMAN" 6 1254.6146 0.13 78643 8459 2 1254.611346 628.3146 T-complex protein 1 subunit gamma OS=Homo sapiens OX=9606 GN=CCT3 PE=1 SV=4 5.9 1848.3 - 1.96E+06 - - - -2.5745 - 1.732 0.406 - 197 1 2 0 -0.0032 10 0 0 0 1.60E+07 1.19E+08 - - - 3.5719 0.9765 221125_WJC_METTL3_EV_vs_WT_F06.08465.08465.3 0.0779 Jun-32 R.IK[136.11]EQEDYIR[166.11].D "sp|Q96L14|C170L_HUMAN,sp|Q5SW79|CE170_HUMAN,tr|E5RGW7|E5RGW7_HUMAN,tr|H0Y2V6|H0Y2V6_HUMAN,tr|E7EMW0|E7EMW0_HUMAN,tr|H0Y4T4|H0Y4T4_HUMAN,tr|E7EWM2|E7EWM2_HUMAN,tr|E5RG47|E5RG47_HUMAN" 8 1210.6313 1.19 78646 8465 3 1210.629405 404.551 Cep170-like protein OS=Homo sapiens OX=9606 GN=CEP170P1 PE=5 SV=2 4.68 1849.1 - 1.93E+06 - - - -1.5422 - 1.483 0.239 - 51.9 1 2 1 -0.0019 9 0 0 0 5.81E+07 4.87E+07 - - - 2.3917 0.9791 221125_WJC_METTL3_EV_vs_WT_F06.08468.08468.2 0.0691 16-Oct K.HLTYENVER[166.11].W "sp|Q15907|RB11B_HUMAN,sp|P62491|RB11A_HUMAN,tr|H3BMH2|H3BMH2_HUMAN,tr|H3BSC1|H3BSC1_HUMAN" 4 1169.5705 1.37 78649 8468 2 1169.56324 585.7925 Ras-related protein Rab-11B OS=Homo sapiens OX=9606 GN=RAB11B PE=1 SV=4 5.4 1849.3 - 4.13E+06 - - - -6.1698 - 1.562 0.368 - 365.5 1 2 0 -0.0072 9 0 0 0 2.95E+08 2.16E+08 - - - 3.047 1 221125_WJC_METTL3_EV_vs_WT_F06.08475.08475.2 1.35E-08 16/28 R.GDVTAEEAAGASPAK[136.11].A sp|P49006|MRP_HUMAN 1 1380.6612 0.9 78653 8475 2 1380.657879 691.3379 MARCKS-related protein OS=Homo sapiens OX=9606 GN=MARCKSL1 PE=1 SV=2 4.14 1849.9 - 4.59E+06 - - - -2.4329 - 2.909 0.671 - 935.3 1 2 0 -0.0034 15 0 0 0 3.45E+08 3.84E+08 - - - 6.6212 0.9666 221125_WJC_METTL3_EV_vs_WT_F06.08478.08478.2 3.57 14-Sep K.SEITELRR.N "sp|P13645|K1C10_HUMAN,tr|A0A1B0GVI3|A0A1B0GVI3_HUMAN" 2 1002.5458 999 78656 8478 2 1002.543674 502.2802 "Keratin, type I cytoskeletal 10 OS=Homo sapiens OX=9606 GN=KRT10 PE=1 SV=6" 5.86 1850.2 - 2.33E+06 - - - -2.1286 - 1.523 0.009 - 202.5 1 2 0 -0.0021 8 0 0 0 6.18E+08 0.00E+00 - - - 0.3756 0.9999 221125_WJC_METTL3_EV_vs_WT_F06.08488.08488.2 9.81E-06 14/20 R.YPSSISSSPQK[136.11].D "sp|Q14157|UBP2L_HUMAN,tr|F8W726|F8W726_HUMAN" 2 1187.5914 2.03 78662 8488 2 1187.591729 594.803 Ubiquitin-associated protein 2-like OS=Homo sapiens OX=9606 GN=UBAP2L PE=1 SV=2 8.59 1851.5 - 1.03E+06 - - - 0.304 - 2.39 0.43 - 735.7 1 2 0 0.0004 11 0 0 0 1.28E+08 6.29E+07 - - - 4.5739 0.9994 221125_WJC_METTL3_EV_vs_WT_F06.08489.08489.3 0.0028 Nov-36 K.QMQVLHPAAR.M sp|P50991|TCPD_HUMAN 1 1149.6077 1.88 78663 8489 3 1149.606306 384.2098 T-complex protein 1 subunit delta OS=Homo sapiens OX=9606 GN=CCT4 PE=1 SV=4 9.76 1851.5 - 1.52E+06 - - - -1.21 - 1.72 0.329 - 186.5 1 2 0 -0.0014 10 0 0 0 2.12E+08 1.13E+08 - - - 3.7915 0.9997 221125_WJC_METTL3_EV_vs_WT_F06.08490.08490.2 5.73E-06 22-Dec K.ETMVTSTTEPSR[166.11].C "sp|P14314|GLU2B_HUMAN,tr|K7ELL7|K7ELL7_HUMAN,tr|A0A0C4DGP4|A0A0C4DGP4_HUMAN" 3 1347.6216 61.91 78664 8490 2 1347.618429 674.8181 Glucosidase 2 subunit beta OS=Homo sapiens OX=9606 GN=PRKCSH PE=1 SV=2 4.53 1851.7 - 941697 - - - -2.3271 - 2.152 0.508 - 446.9 1 2 0 -0.0031 12 0 0 0 9.23E+08 1.49E+07 - - - 4.8086 0.9998 221125_WJC_METTL3_EV_vs_WT_F06.08500.08500.2 7.84E-06 24-Dec K.SGNIPAGTTVDTK.L sp|Q9UKV8|AGO2_HUMAN 1 1259.6357 0.2 78671 8500 2 1259.634193 630.8251 Protein argonaute-2 OS=Homo sapiens OX=9606 GN=AGO2 PE=1 SV=3 5.55 1852.9 - 1.55E+06 - - - -1.2321 - 2.048 0.486 - 419.7 1 2 0 -0.0016 13 0 0 0 5.02E+07 2.57E+08 - - - 4.47 0.9986 221125_WJC_METTL3_EV_vs_WT_F06.08504.08504.3 0.00494 Sep-32 K.HLTYENVER.W "sp|Q15907|RB11B_HUMAN,sp|P62491|RB11A_HUMAN,tr|H3BMH2|H3BMH2_HUMAN,tr|H3BSC1|H3BSC1_HUMAN" 4 1159.5622 1.01 78674 8504 3 1159.560113 387.528 Ras-related protein Rab-11B OS=Homo sapiens OX=9606 GN=RAB11B PE=1 SV=4 5.4 1853.2 - 1.31E+07 - - - -1.7877 - 1.633 0.3 - 163.5 1 2 0 -0.0021 9 0 0 0 2.00E+08 1.99E+08 - - - 3.3622 0.9927 221125_WJC_METTL3_EV_vs_WT_F06.08506.08506.2 0.0018 18-Oct K.FNQVESDKLR.M sp|Q10471|GALT2_HUMAN 1 1234.6306 1.47 78676 8506 2 1234.633932 618.3226 Polypeptide N-acetylgalactosaminyltransferase 2 OS=Homo sapiens OX=9606 GN=GALNT2 PE=1 SV=1 6.07 1853.4 - 1.30E+06 - - - 2.6988 - 2.22 0.405 - 395.1 1 2 1 0.0033 10 0 0 0 3.02E+07 2.06E+07 - - - 4.2574 0.9957 221125_WJC_METTL3_EV_vs_WT_F06.08512.08512.3 0.000217 16/48 D.AHPTLVTYADHSK[136.11].L "sp|Q86U44|MTA70_HUMAN,tr|F5H6D8|F5H6D8_HUMAN,tr|H0YFV6|H0YFV6_HUMAN,tr|B4DTN4|B4DTN4_HUMAN" 4 1446.7347 0.02 78680 8512 3 1446.734049 483.2522 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 6.96 1854 - 4.22E+06 - - - -0.4348 - 2.376 0.471 - 201.9 1 1 0 -0.0006 13 0 0 0 1.92E+06 1.11E+08 - - - 6.1374 1 221125_WJC_METTL3_EV_vs_WT_F06.08518.08518.2 2.81E-10 17/28 R.GDVTAEEAAGASPAK.A sp|P49006|MRP_HUMAN 1 1372.647 0.9 78685 8518 2 1372.646237 687.3308 MARCKS-related protein OS=Homo sapiens OX=9606 GN=MARCKSL1 PE=1 SV=2 4.14 1854.6 - 1.07E+07 - - - -0.5835 - 3.318 0.653 - 1244.1 1 2 0 -0.0008 15 0 0 0 3.45E+08 3.84E+08 - - - 6.8125 0.9995 221125_WJC_METTL3_EV_vs_WT_F06.08520.08520.2 0.0168 16-Aug K.STMQELNSR.L sp|P35527|K1C9_HUMAN 1 1064.4921 1739.65 78686 8520 2 1064.491194 533.2533 "Keratin, type I cytoskeletal 9 OS=Homo sapiens OX=9606 GN=KRT9 PE=1 SV=3" 5.72 1854.8 - 7.77E+06 - - - -0.8117 - 1.685 0.345 - 251.8 1 2 0 -0.0009 9 0 0 0 1.80E+08 1.04E+05 - - - 3.0984 0.997 221125_WJC_METTL3_EV_vs_WT_F06.08524.08524.2 0.00179 18-Aug K.YALTGDEVK[136.11]K[136.11].L "sp|P62701|RS4X_HUMAN,sp|P22090|RS4Y1_HUMAN,sp|Q8TD47|RS4Y2_HUMAN,tr|C9JEH7|C9JEH7_HUMAN" 4 1138.6205 0.93 78690 8524 2 1138.62413 570.3175 "40S ribosomal protein S4, X isoform OS=Homo sapiens OX=9606 GN=RPS4X PE=1 SV=2" 6.07 1855.2 - 484752 - - - 3.1969 - 1.5 0.368 - 175.2 1 2 0 0.0036 10 0 0 0 4.85E+07 5.24E+07 - - - 2.8897 0.9999 221125_WJC_METTL3_EV_vs_WT_F06.08529.08529.3 0.000116 Nov-36 K.YALTGDEVK[136.11]K[136.11].L "sp|P62701|RS4X_HUMAN,sp|P22090|RS4Y1_HUMAN,sp|Q8TD47|RS4Y2_HUMAN,tr|C9JEH7|C9JEH7_HUMAN" 4 1138.6205 0.001 78693 8529 3 1138.619715 380.5474 "40S ribosomal protein S4, X isoform OS=Homo sapiens OX=9606 GN=RPS4X PE=1 SV=2" 6.07 1855.7 - 2.23E+06 - - - -0.6806 - 1.826 0.423 - 106.5 1 2 0 -0.0008 10 0 0 0 0.00E+00 2.21E+08 - - - 5.0143 0.9999 221125_WJC_METTL3_EV_vs_WT_F06.08530.08530.2 0.196 13/24 K.QAASGLVGQENAR[166.11].E sp|Q9Y265|RUVB1_HUMAN 1 1309.6614 0.76 78694 8530 2 1309.660495 655.838 RuvB-like 1 OS=Homo sapiens OX=9606 GN=RUVBL1 PE=1 SV=1 6 1855.8 - 782575 - - - -0.6887 - 2.535 0.461 - 543.4 1 2 0 -0.0009 13 0 0 0 5.74E+07 7.52E+07 - - - 4.833 0.9999 221125_WJC_METTL3_EV_vs_WT_F06.08534.08534.2 4.01E-06 22-Nov K.SGGVGGSNTNWK.T "sp|P27694|RFA1_HUMAN,tr|I3L4R8|I3L4R8_HUMAN" 2 1162.5367 1.26 78696 8534 2 1162.535665 582.2756 Replication protein A 70 kDa DNA-binding subunit OS=Homo sapiens OX=9606 GN=RPA1 PE=1 SV=2 8.47 1856.4 - 7.90E+06 - - - -0.8903 - 2.316 0.569 - 347.2 1 2 0 -0.001 12 0 0 0 3.08E+08 2.44E+08 - - - 5.4531 0.9999 221125_WJC_METTL3_EV_vs_WT_F06.08535.08535.2 0.022 22-Nov R.SAEYGSSLQSSR.S sp|Q6KB66|K2C80_HUMAN 1 1270.579 999 78697 8535 2 1270.577531 636.2968 "Keratin, type II cytoskeletal 80 OS=Homo sapiens OX=9606 GN=KRT80 PE=1 SV=2" 5.72 1856.4 - 1.98E+06 - - - -1.1239 - 2.39 0.501 - 536.9 1 2 0 -0.0014 12 0 0 0 5.43E+07 0.00E+00 - - - 5.0335 0.9898 221125_WJC_METTL3_EV_vs_WT_F06.08540.08540.2 0.000127 15/22 R.HPQPGAVELAAK.H "sp|P27708|PYR1_HUMAN,tr|F8VPD4|F8VPD4_HUMAN,tr|H7C2E4|H7C2E4_HUMAN" 3 1216.6564 0.4 78702 8540 2 1216.663832 609.3355 CAD protein OS=Homo sapiens OX=9606 GN=CAD PE=1 SV=3 6.75 1857 - 798436 - - - 6.0913 - 2.289 0.35 - 597.1 1 2 0 0.0074 12 0 0 0 1.00E+07 2.51E+07 - - - 3.8027 0.9993 221125_WJC_METTL3_EV_vs_WT_F06.08543.08543.2 0.0108 16-Dec K.REFIQEPAK.N "sp|O14744|ANM5_HUMAN,tr|C9JSX3|C9JSX3_HUMAN,tr|G3V580|G3V580_HUMAN,tr|G3V2L6|G3V2L6_HUMAN,tr|G3V5L5|G3V5L5_HUMAN" 5 1116.5928 3.68 78705 8543 2 1116.594906 559.3037 Protein arginine N-methyltransferase 5 OS=Homo sapiens OX=9606 GN=PRMT5 PE=1 SV=4 6.14 1857.4 - 184192 - - - 1.9237 - 2.156 0.307 - 787.3 1 2 0 0.0021 9 0 0 0 3.57E+07 9.70E+06 - - - 3.5304 0.9999 221125_WJC_METTL3_EV_vs_WT_F06.08548.08548.3 0.0277 13/40 R.LQIEESSK[136.11]PVR[166.11].L sp|P13984|T2FB_HUMAN 1 1302.7262 1.29 78708 8548 3 1302.72585 435.2494 General transcription factor IIF subunit 2 OS=Homo sapiens OX=9606 GN=GTF2F2 PE=1 SV=2 6.14 1857.8 - 4.76E+06 - - - -0.2955 - 2.572 0.347 - 466.7 1 2 0 -0.0004 11 0 0 0 2.04E+08 1.59E+08 - - - 5.0923 0.9998 221125_WJC_METTL3_EV_vs_WT_F06.08549.08549.2 0.000117 18-Dec R.R[166.11]GTTVYLC[160.03]EK[136.11].R "sp|Q9Y2L1|RRP44_HUMAN,tr|F2Z2C0|F2Z2C0_HUMAN,tr|G3V1J5|G3V1J5_HUMAN" 3 1243.635 1.67 78709 8549 2 1243.635583 622.8248 Exosome complex exonuclease RRP44 OS=Homo sapiens OX=9606 GN=DIS3 PE=1 SV=2 8.2 1857.9 - 2.77E+06 - - - 0.4865 - 2.36 0.357 - 464.4 1 2 0 0.0006 10 0 0 0 9.49E+07 5.67E+07 - - - 4.0744 0.9925 221125_WJC_METTL3_EV_vs_WT_F06.08550.08550.2 3.3 12-Jul R.REQWLQK.L "sp|Q9NSI2|SLX9_HUMAN,tr|C9JJU7|C9JJU7_HUMAN" 2 986.5298 0.35 78710 8550 2 986.529652 494.2722 Ribosome biogenesis protein SLX9 homolog OS=Homo sapiens OX=9606 GN=SLX9 PE=1 SV=2 8.75 1858 - 2.08E+06 - - - -0.1135 - 1.275 0.135 - 255.7 1 2 0 -0.0001 7 0 0 0 3.60E+07 1.04E+08 - - - 0.8079 0.9999 221125_WJC_METTL3_EV_vs_WT_F06.08551.08551.2 0.000142 15/24 K.QAASGLVGQENAR.E sp|Q9Y265|RUVB1_HUMAN 1 1299.6531 0.76 78711 8551 2 1299.65208 650.8338 RuvB-like 1 OS=Homo sapiens OX=9606 GN=RUVBL1 PE=1 SV=1 6 1858.1 - 1.93E+06 - - - -0.8056 - 2.615 0.484 - 769.7 1 2 0 -0.001 13 0 0 0 5.74E+07 7.52E+07 - - - 5.0826 0.9824 221125_WJC_METTL3_EV_vs_WT_F06.08554.08554.2 0.0496 22-Jul R.GAGWTGHVAGTR[166.11].K sp|Q15274|NADC_HUMAN 1 1178.582 0.44 78714 8554 2 1178.579135 590.2983 Nicotinate-nucleotide pyrophosphorylase [carboxylating] OS=Homo sapiens OX=9606 GN=QPRT PE=1 SV=3 9.76 1858.4 - 414321 - - - -2.4513 - 1.095 0.23 - 116.2 1 2 0 -0.0029 12 0 0 0 1.49E+07 3.41E+07 - - - 0.9777 0.9265 221125_WJC_METTL3_EV_vs_WT_F06.08560.08560.2 0.0965 18-Nov K.LLEQYK[136.11]EESK[136.11].K "sp|Q00839|HNRPU_HUMAN,tr|A0A1W2PQL0|A0A1W2PQL0_HUMAN,tr|A0A1W2PPL4|A0A1W2PPL4_HUMAN,tr|Q5RI18|Q5RI18_HUMAN,tr|A0A1W2PP35|A0A1W2PP35_HUMAN,tr|A0A1W2PPS1|A0A1W2PPS1_HUMAN,tr|A0A1W2PPH7|A0A1W2PPH7_HUMAN,tr|A0A1W2PQD4|A0A1W2PQD4_HUMAN,tr|A0A1W2PP34|A0A1W2PP34_HUMAN,tr|A0A1X7SBS1|A0A1X7SBS1_HUMAN" 10 1281.6787 1 78718 8560 2 1281.686664 641.8466 Heterogeneous nuclear ribonucleoprotein U OS=Homo sapiens OX=9606 GN=HNRNPU PE=1 SV=6 4.79 1859.1 - 1.82E+06 - - - 6.188 - 2.235 0.421 - 420.3 1 2 1 0.0079 10 0 0 0 1.05E+09 1.05E+09 - - - 4.3929 0.9652 221125_WJC_METTL3_EV_vs_WT_F06.08562.08562.3 0.139 Sep-32 R.EEVEHMIQK[136.11].N "sp|Q9UL40|ZN346_HUMAN,tr|B7Z6B6|B7Z6B6_HUMAN,tr|D6RJ07|D6RJ07_HUMAN,tr|B7Z6Q2|B7Z6Q2_HUMAN" 4 1149.558 1.08 78720 8562 3 1149.559772 384.1933 Zinc finger protein 346 OS=Homo sapiens OX=9606 GN=ZNF346 PE=1 SV=1 4.75 1859.2 - 1.77E+06 - - - 1.5771 - 1.408 0.155 - 91.3 1 2 0 0.0018 9 0 0 0 2.59E+07 2.41E+07 - - - 1.2988 0.9994 221125_WJC_METTL3_EV_vs_WT_F06.08563.08563.2 0.0388 16-Nov K.REFIQEPAK.N "sp|O14744|ANM5_HUMAN,tr|C9JSX3|C9JSX3_HUMAN,tr|G3V580|G3V580_HUMAN,tr|G3V2L6|G3V2L6_HUMAN,tr|G3V5L5|G3V5L5_HUMAN" 5 1116.5928 3.68 78721 8563 2 1116.59373 559.3037 Protein arginine N-methyltransferase 5 OS=Homo sapiens OX=9606 GN=PRMT5 PE=1 SV=4 6.14 1859.3 - 1.68E+06 - - - 0.8705 - 2.19 0.235 - 623.3 1 2 0 0.001 9 0 0 0 3.57E+07 9.70E+06 - - - 3.0443 0.9897 221125_WJC_METTL3_EV_vs_WT_F06.08565.08565.2 0.0675 20-Dec R.ASR[166.11]EEILAQAK[136.11].E sp|P35579|MYH9_HUMAN 1 1232.6844 1.17 78723 8565 2 1232.684508 617.3495 Myosin-9 OS=Homo sapiens OX=9606 GN=MYH9 PE=1 SV=4 6.19 1859.5 - 1.37E+06 - - - 0.112 - 2.497 0.125 - 536.7 1 2 1 0.0001 11 0 0 0 4.81E+07 4.12E+07 - - - 2.4397 0.9961 221125_WJC_METTL3_EV_vs_WT_F06.08567.08567.2 0.0678 15/20 R.ASREEILAQAK.E sp|P35579|MYH9_HUMAN 1 1214.6619 1.17 78725 8567 2 1214.663008 608.3382 Myosin-9 OS=Homo sapiens OX=9606 GN=MYH9 PE=1 SV=4 6.19 1859.6 - 1.09E+06 - - - 0.9122 - 2.474 0.298 - 832.7 1 2 1 0.0011 11 0 0 0 4.81E+07 4.12E+07 - - - 3.6922 0.9997 221125_WJC_METTL3_EV_vs_WT_F06.08570.08570.2 0.00114 16-Oct R.EEVEHMIQK[136.11].N "sp|Q9UL40|ZN346_HUMAN,tr|B7Z6B6|B7Z6B6_HUMAN,tr|D6RJ07|D6RJ07_HUMAN,tr|B7Z6Q2|B7Z6Q2_HUMAN" 4 1149.558 0.75 78728 8570 2 1149.557048 575.7863 Zinc finger protein 346 OS=Homo sapiens OX=9606 GN=ZNF346 PE=1 SV=1 4.75 1859.9 - 858064 - - - -0.7925 - 2.031 0.34 - 314.5 1 2 0 -0.0009 9 0 0 0 1.42E+07 1.89E+07 - - - 3.6018 0.9999 221125_WJC_METTL3_EV_vs_WT_F06.08572.08572.2 2.95E-05 22-Dec R.ASLGQASIQNGK[136.11].D "sp|Q7KZI7|MARK2_HUMAN,tr|E7ETY4|E7ETY4_HUMAN,tr|A0A7I2YQF3|A0A7I2YQF3_HUMAN,tr|A0A7I2YQR3|A0A7I2YQR3_HUMAN,tr|E9PC69|E9PC69_HUMAN,tr|A0A7I2V3R3|A0A7I2V3R3_HUMAN" 6 1180.6291 0.95 78730 8572 2 1180.629146 591.3219 Serine\threonine-protein kinase MARK2 OS=Homo sapiens OX=9606 GN=MARK2 PE=1 SV=2 8.8 1860.1 - 397293 - - - -0.0034 - 2.533 0.461 - 368.6 1 2 0 0 12 0 0 0 3.11E+07 3.29E+07 - - - 4.8914 0.9996 221125_WJC_METTL3_EV_vs_WT_F06.08574.08574.2 4.04E-05 16-Aug K.QDSGHLDLR[166.11].N "sp|Q86U44|MTA70_HUMAN,tr|B4E349|B4E349_HUMAN,tr|F5H6D8|F5H6D8_HUMAN,tr|B4DTN4|B4DTN4_HUMAN" 4 1049.5129 0.02 78731 8574 2 1049.514209 525.7637 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 5.21 1860.4 - 3.29E+06 - - - 1.2082 - 1.796 0.409 - 199 1 2 0 0.0013 9 0 0 0 1.74E+06 8.60E+07 - - - 3.7555 0.9994 221125_WJC_METTL3_EV_vs_WT_F06.08576.08576.3 0.00186 Dec-40 R.LQIEESSKPVR.L sp|P13984|T2FB_HUMAN 1 1284.7038 1.28 78732 8576 3 1284.703629 429.2419 General transcription factor IIF subunit 2 OS=Homo sapiens OX=9606 GN=GTF2F2 PE=1 SV=2 6.14 1860.6 - 1.40E+07 - - - -0.1059 - 2.386 0.241 - 253.1 1 2 0 -0.0001 11 0 0 0 2.04E+08 1.59E+08 - - - 3.6973 1 221125_WJC_METTL3_EV_vs_WT_F06.08577.08577.3 7.44E-06 Dec-40 R.GLDNTEFQGKR.M "sp|Q9BWF3|RBM4_HUMAN,sp|Q9BQ04|RBM4B_HUMAN,tr|E9PB51|E9PB51_HUMAN" 3 1263.6208 1.46 78733 8577 3 1263.620694 422.2142 RNA-binding protein 4 OS=Homo sapiens OX=9606 GN=RBM4 PE=1 SV=1 6.07 1860.6 - 1.31E+07 - - - -0.0554 - 2.305 0.55 - 166 1 2 0 -0.0001 11 0 0 0 1.61E+08 1.10E+08 - - - 7.0443 0.9999 221125_WJC_METTL3_EV_vs_WT_F06.08578.08578.3 0.000859 Oct-36 R.RGTTVYLC[160.03]EK.R "sp|Q9Y2L1|RRP44_HUMAN,tr|F2Z2C0|F2Z2C0_HUMAN,tr|G3V1J5|G3V1J5_HUMAN" 3 1225.6125 2.11 78734 8578 3 1225.612887 409.5448 Exosome complex exonuclease RRP44 OS=Homo sapiens OX=9606 GN=DIS3 PE=1 SV=2 8.2 1860.7 - 4.45E+06 - - - 0.3092 - 1.905 0.456 - 158.6 1 2 0 0.0004 10 0 0 0 7.98E+07 3.79E+07 - - - 5.506 0.8962 221125_WJC_METTL3_EV_vs_WT_F06.08579.08579.3 0.0574 Jul-36 K.EMDEEDK[136.11]AFK[136.11].Q sp|Q9Y2S6|TMA7_HUMAN 1 1256.5566 0.53 78735 8579 3 1256.561711 419.8595 Translation machinery-associated protein 7 OS=Homo sapiens OX=9606 GN=TMA7 PE=1 SV=1 4.18 1860.7 - 2.98E+06 - - - 4.0921 - 1.411 0.272 - 46.6 1 2 1 0.0051 10 0 0 0 4.82E+07 9.09E+07 - - - 2.5766 0.9998 221125_WJC_METTL3_EV_vs_WT_F06.08580.08580.3 0.000497 Sep-36 R.R[166.11]GTTVYLC[160.03]EK[136.11].R "sp|Q9Y2L1|RRP44_HUMAN,tr|F2Z2C0|F2Z2C0_HUMAN,tr|G3V1J5|G3V1J5_HUMAN" 3 1243.635 2.8 78736 8580 3 1243.634998 415.5523 Exosome complex exonuclease RRP44 OS=Homo sapiens OX=9606 GN=DIS3 PE=1 SV=2 8.2 1860.8 - 2.86E+06 - - - 0.0161 - 1.918 0.36 - 119.4 1 2 0 0 10 0 0 0 1.20E+08 4.30E+07 - - - 4.4557 0.9991 221125_WJC_METTL3_EV_vs_WT_F06.08583.08583.2 0.0183 18-Jul R.GNEYQPSNIK[136.11].R "sp|Q9BQ48|RM34_HUMAN,tr|M0R226|M0R226_HUMAN" 2 1156.5604 2.07 78739 8583 2 1156.561339 579.2875 "39S ribosomal protein L34, mitochondrial OS=Homo sapiens OX=9606 GN=MRPL34 PE=1 SV=1" 6 1861.1 - 576231 - - - 0.8102 - 1.622 0.305 - 202 1 2 0 0.0009 10 0 0 0 1.74E+07 8.41E+06 - - - 2.6435 0.9962 221125_WJC_METTL3_EV_vs_WT_F06.08587.08587.3 0.00514 14/36 H.SIVEC[160.03]DPVRK.E "sp|P52732|KIF11_HUMAN,tr|A0A7I2YQY4|A0A7I2YQY4_HUMAN,tr|A0A7I2V3V3|A0A7I2V3V3_HUMAN" 3 1201.6125 1.84 78741 8587 3 1201.613182 401.5448 Kinesin-like protein KIF11 OS=Homo sapiens OX=9606 GN=KIF11 PE=1 SV=2 5.79 1861.6 - 2.24E+06 - - - 0.5609 - 2.333 0.472 - 233.7 1 1 0 0.0007 10 0 0 0 1.52E+08 8.22E+07 - - - 6.2762 0.9998 221125_WJC_METTL3_EV_vs_WT_F06.08588.08588.3 1.57E-06 13/44 R.VVANSK[136.11]ESYELR[166.11].Y "sp|P35268|RL22_HUMAN,tr|K7ERI7|K7ERI7_HUMAN,tr|K7EMH1|K7EMH1_HUMAN" 3 1411.7426 0.8 78742 8588 3 1411.744148 471.5881 60S ribosomal protein L22 OS=Homo sapiens OX=9606 GN=RPL22 PE=1 SV=2 6.11 1861.7 - 1.45E+06 - - - 1.0866 - 2.325 0.48 - 253.8 1 2 1 0.0015 12 0 0 0 1.37E+07 1.71E+07 - - - 6.2298 1 221125_WJC_METTL3_EV_vs_WT_F06.08590.08590.2 3.05E-09 13/26 K.LAVDEEENADNNTK.A "sp|P02786|TFR1_HUMAN,tr|F8WBE5|F8WBE5_HUMAN" 2 1560.6904 1.48 78744 8590 2 1560.692591 781.3525 Transferrin receptor protein 1 OS=Homo sapiens OX=9606 GN=TFRC PE=1 SV=2 3.83 1861.9 - 358164 - - - 1.4295 - 2.961 0.615 - 492.7 1 2 0 0.0022 14 0 0 0 8.54E+06 5.78E+06 - - - 6.3068 0.9999 221125_WJC_METTL3_EV_vs_WT_F06.08593.08593.2 0.000196 20-Nov R.GLDNTEFQGKR.M "sp|Q9BWF3|RBM4_HUMAN,sp|Q9BQ04|RBM4B_HUMAN,tr|E9PB51|E9PB51_HUMAN" 3 1263.6208 1.7 78745 8593 2 1263.622029 632.8177 RNA-binding protein 4 OS=Homo sapiens OX=9606 GN=RBM4 PE=1 SV=1 6.07 1862.3 - 1.44E+06 - - - 1.0011 - 2.438 0.528 - 398.6 1 2 0 0.0013 11 0 0 0 2.02E+07 1.19E+07 - - - 5.3513 0.9995 221125_WJC_METTL3_EV_vs_WT_F06.08595.08595.2 0.00315 18-Oct R.VHELNEEIGK[136.11].L "sp|Q9Y383|LC7L2_HUMAN,sp|Q9NQ29|LUC7L_HUMAN,tr|A8MYV2|A8MYV2_HUMAN,tr|B8ZZ09|B8ZZ09_HUMAN,tr|A0A0A6YYJ8|A0A0A6YYJ8_HUMAN,tr|B8ZZ10|B8ZZ10_HUMAN" 6 1174.6074 4.91 78747 8595 2 1174.608858 588.311 Putative RNA-binding protein Luc7-like 2 OS=Homo sapiens OX=9606 GN=LUC7L2 PE=1 SV=2 4.75 1862.4 - 2.41E+06 - - - 1.2821 - 2.394 0.275 - 430.9 1 2 0 0.0015 10 0 0 0 1.94E+08 3.95E+07 - - - 3.5084 0.9978 221125_WJC_METTL3_EV_vs_WT_F06.08596.08596.2 0.000461 16-Oct R.EEVEHMIQK.N "sp|Q9UL40|ZN346_HUMAN,tr|B7Z6B6|B7Z6B6_HUMAN,tr|D6RJ07|D6RJ07_HUMAN,tr|B7Z6Q2|B7Z6Q2_HUMAN" 4 1141.5438 0.77 78748 8596 2 1141.547 571.7792 Zinc finger protein 346 OS=Homo sapiens OX=9606 GN=ZNF346 PE=1 SV=1 4.75 1862.5 - 1.86E+06 - - - 2.8391 - 1.322 0.419 - 249.4 1 2 0 0.0032 9 0 0 0 1.42E+07 1.85E+07 - - - 2.9423 0.9529 221125_WJC_METTL3_EV_vs_WT_F06.08597.08597.2 0.0443 18-Sep H.SIVEC[160.03]DPVRK.E "sp|P52732|KIF11_HUMAN,tr|A0A7I2YQY4|A0A7I2YQY4_HUMAN,tr|A0A7I2V3V3|A0A7I2V3V3_HUMAN" 3 1201.6125 4.1 78749 8597 2 1201.614795 601.8135 Kinesin-like protein KIF11 OS=Homo sapiens OX=9606 GN=KIF11 PE=1 SV=2 5.79 1862.7 - 645215 - - - 1.9033 - 1.754 0.367 - 263.3 1 1 0 0.0023 10 0 0 0 2.11E+07 5.14E+06 - - - 3.3194 0.873 221125_WJC_METTL3_EV_vs_WT_F06.08599.08599.2 0.225 16-Sep Q.IEESSKPVR.L sp|P13984|T2FB_HUMAN 1 1043.5611 1.73 78751 8599 2 1043.562759 522.7878 General transcription factor IIF subunit 2 OS=Homo sapiens OX=9606 GN=GTF2F2 PE=1 SV=2 6.14 1862.9 - 379385 - - - 1.5668 - 1.647 0.22 - 262.5 1 1 0 0.0016 9 0 0 0 5.44E+06 3.14E+06 - - - 2.1089 0.9976 221125_WJC_METTL3_EV_vs_WT_F06.08603.08603.3 0.407 Aug-32 K.EQELDTLK[136.11]R[166.11].K sp|P11388|TOP2A_HUMAN 1 1148.6156 0.001 78753 8603 3 1148.617182 383.8792 DNA topoisomerase 2-alpha OS=Homo sapiens OX=9606 GN=TOP2A PE=1 SV=3 4.68 1863.4 - 1.57E+06 - - - 1.3582 - 2.041 0.21 - 85.3 2 2 0 0.0016 9 0 0 0 0.00E+00 1.99E+07 - - - 2.8917 0.9999 221125_WJC_METTL3_EV_vs_WT_F06.08604.08604.3 2.46E-06 13/44 K.IRDEMVATEQER.T "sp|P16615|AT2A2_HUMAN,tr|H7C5W9|H7C5W9_HUMAN" 2 1475.7038 0.69 78754 8604 3 1475.704131 492.9086 Sarcoplasmic\endoplasmic reticulum calcium ATPase 2 OS=Homo sapiens OX=9606 GN=ATP2A2 PE=1 SV=1 4.41 1863.5 - 1.19E+06 - - - 0.1958 - 2.54 0.482 - 344 1 2 1 0.0003 12 0 0 0 3.65E+07 5.32E+07 - - - 6.4976 0.9999 221125_WJC_METTL3_EV_vs_WT_F06.08605.08605.3 0.000429 Oct-40 K.IDRPEAISEER.L "sp|Q9Y6B6|SAR1B_HUMAN,tr|D6RD69|D6RD69_HUMAN,tr|D6R9R5|D6R9R5_HUMAN,tr|Q9H029|Q9H029_HUMAN" 4 1313.6575 1.22 78755 8605 3 1313.656789 438.8931 GTP-binding protein SAR1b OS=Homo sapiens OX=9606 GN=SAR1B PE=1 SV=1 4.41 1863.6 - 939418 - - - -0.574 - 2.342 0.397 - 204.7 1 2 0 -0.0008 11 0 0 0 1.53E+09 1.26E+09 - - - 5.3835 0.9911 221125_WJC_METTL3_EV_vs_WT_F06.08606.08606.3 0.021 Oct-44 R.SAEEVEEIKAEK.E sp|Q8WUA2|PPIL4_HUMAN 1 1360.6722 0.78 78756 8606 3 1360.674311 454.5647 Peptidyl-prolyl cis-trans isomerase-like 4 OS=Homo sapiens OX=9606 GN=PPIL4 PE=1 SV=1 4.32 1863.6 - 984666 - - - 1.5588 - 1.64 0.288 - 108.6 1 2 1 0.0021 12 0 0 0 1.19E+07 1.52E+07 - - - 3.1216 0.9961 221125_WJC_METTL3_EV_vs_WT_F06.08608.08608.2 0.000425 18-Aug K.TLIPHTDGEK.L "sp|Q01664|TFAP4_HUMAN,tr|I3L254|I3L254_HUMAN" 2 1109.5717 0.53 78758 8608 2 1109.575161 555.7931 Transcription factor AP-4 OS=Homo sapiens OX=9606 GN=TFAP4 PE=1 SV=2 5.29 1863.9 - 486172 - - - 3.13 - 1.366 0.363 - 241 1 2 0 0.0035 10 0 0 0 9.88E+06 1.88E+07 - - - 2.5916 0.9999 221125_WJC_METTL3_EV_vs_WT_F06.08610.08610.2 1.80E-05 26-Sep R.AALMESQGQQQEER[166.11].G "sp|Q14980|NUMA1_HUMAN,tr|A0A087WY61|A0A087WY61_HUMAN" 2 1613.7343 1.4 78760 8610 2 1613.733432 807.8744 Nuclear mitotic apparatus protein 1 OS=Homo sapiens OX=9606 GN=NUMA1 PE=1 SV=2 4.25 1864.1 - 118640 - - - -0.5404 - 1.913 0.539 - 190.4 1 2 0 -0.0009 14 0 0 0 1.26E+06 9.01E+05 - - - 4.6496 0.9996 221125_WJC_METTL3_EV_vs_WT_F06.08613.08613.3 5.49E-05 Nov-44 K.IR[166.11]DEMVATEQER[166.11].T "sp|P16615|AT2A2_HUMAN,tr|H7C5W9|H7C5W9_HUMAN" 2 1495.7204 0.62 78761 8613 3 1495.72348 499.5807 Sarcoplasmic\endoplasmic reticulum calcium ATPase 2 OS=Homo sapiens OX=9606 GN=ATP2A2 PE=1 SV=1 4.41 1864.5 - 2.56E+06 - - - 2.0712 - 2.587 0.443 - 269.9 1 2 1 0.0031 12 0 0 0 3.66E+07 5.90E+07 - - - 6.1128 0.9987 221125_WJC_METTL3_EV_vs_WT_F06.08614.08614.3 0.00657 Dec-44 K.VGTIDDDPEYR[166.11]K[136.11].F sp|Q9BZI7|REN3B_HUMAN 1 1424.6902 1.14 78762 8614 3 1424.693074 475.904 Regulator of nonsense transcripts 3B OS=Homo sapiens OX=9606 GN=UPF3B PE=1 SV=1 4.23 1864.6 - 1.32E+06 - - - 1.9864 - 2.181 0.26 - 232.3 1 2 0 0.0028 12 0 0 0 3.83E+07 3.36E+07 - - - 3.5994 0.9999 221125_WJC_METTL3_EV_vs_WT_F06.08615.08615.3 0.00238 13/44 K.VGTIDDDPEYRK.F sp|Q9BZI7|REN3B_HUMAN 1 1406.6678 1.14 78763 8615 3 1406.668963 469.8965 Regulator of nonsense transcripts 3B OS=Homo sapiens OX=9606 GN=UPF3B PE=1 SV=1 4.23 1864.7 - 1.44E+06 - - - 0.8453 - 2.219 0.403 - 192.3 1 2 0 0.0012 12 0 0 0 3.83E+07 3.36E+07 - - - 5.242 0.9968 221125_WJC_METTL3_EV_vs_WT_F06.08616.08616.2 0.138 16-Jul R.HSVGVVIGR[166.11].S "sp|Q92945|FUBP2_HUMAN,tr|M0R0I5|M0R0I5_HUMAN,tr|M0R0C6|M0R0C6_HUMAN,tr|A0A087WTP3|A0A087WTP3_HUMAN" 4 932.5431 0.81 78764 8616 2 932.543693 467.2788 Far upstream element-binding protein 2 OS=Homo sapiens OX=9606 GN=KHSRP PE=1 SV=4 9.76 1864.8 - 737455 - - - 0.6155 - 1.556 0.163 - 91.9 1 2 0 0.0006 9 0 0 0 9.71E+06 1.20E+07 - - - 1.5238 0.9998 221125_WJC_METTL3_EV_vs_WT_F06.08617.08617.3 0.00632 15/44 R.SLGGPLSSHPSR.Y "sp|Q9C0C7|AMRA1_HUMAN,tr|A0A075B6T1|A0A075B6T1_HUMAN" 2 1193.6153 0.27 78765 8617 3 1193.614987 398.879 Activating molecule in BECN1-regulated autophagy protein 1 OS=Homo sapiens OX=9606 GN=AMBRA1 PE=1 SV=2 9.49 1864.9 - 544833 - - - -0.2497 - 2.028 0.354 - 237.7 1 2 0 -0.0003 12 0 0 0 8.47E+06 3.10E+07 - - - 4.4465 1 221125_WJC_METTL3_EV_vs_WT_F06.08618.08618.2 6.71E-09 16/26 K.LAVDEEENADNNTK[136.11].A "sp|P02786|TFR1_HUMAN,tr|F8WBE5|F8WBE5_HUMAN" 2 1568.7046 1.48 78766 8618 2 1568.704432 785.3596 Transferrin receptor protein 1 OS=Homo sapiens OX=9606 GN=TFRC PE=1 SV=2 3.83 1865.1 - 363958 - - - -0.0816 - 3.135 0.673 - 703.7 1 2 0 -0.0001 14 0 0 0 8.54E+06 5.78E+06 - - - 6.8791 0.9996 221125_WJC_METTL3_EV_vs_WT_F06.08623.08623.3 0.000366 Sep-36 R.VHELNEEIGK[136.11].L "sp|Q9Y383|LC7L2_HUMAN,sp|Q9NQ29|LUC7L_HUMAN,tr|A8MYV2|A8MYV2_HUMAN,tr|B8ZZ09|B8ZZ09_HUMAN,tr|A0A0A6YYJ8|A0A0A6YYJ8_HUMAN,tr|B8ZZ10|B8ZZ10_HUMAN" 6 1174.6074 4.04 78770 8623 3 1174.607284 392.5431 Putative RNA-binding protein Luc7-like 2 OS=Homo sapiens OX=9606 GN=LUC7L2 PE=1 SV=2 4.75 1865.7 - 3.45E+06 - - - -0.0579 - 2.169 0.282 - 159.8 1 2 0 -0.0001 10 0 0 0 4.08E+08 1.01E+08 - - - 3.9452 0.9998 221125_WJC_METTL3_EV_vs_WT_F06.08625.08625.3 0.00262 Nov-44 R.YLAEVAAGDDK[136.11]K[136.11].G "sp|P63104|1433Z_HUMAN,tr|H0YB80|H0YB80_HUMAN,tr|E7EX29|E7EX29_HUMAN,tr|B7Z2E6|B7Z2E6_HUMAN,tr|B0AZS6|B0AZS6_HUMAN" 5 1294.674 2.08 78771 8625 3 1294.674117 432.5653 14-3-3 protein zeta\delta OS=Homo sapiens OX=9606 GN=YWHAZ PE=1 SV=1 4.56 1865.9 - 1.30E+06 - - - 0.1043 - 1.847 0.388 - 116.3 1 2 0 0.0001 12 0 0 0 1.37E+08 6.59E+07 - - - 4.5665 1 221125_WJC_METTL3_EV_vs_WT_F06.08626.08626.2 8.04E-08 15/24 R.APGAEEDDSELQR.A "sp|Q53F19|NCBP3_HUMAN,tr|K7ELP6|K7ELP6_HUMAN" 2 1415.6165 1.71 78772 8626 2 1415.617253 708.8155 Nuclear cap-binding protein subunit 3 OS=Homo sapiens OX=9606 GN=NCBP3 PE=1 SV=2 3.83 1866.1 - 413771 - - - 0.5559 - 2.914 0.686 - 1018.1 1 2 0 0.0008 13 0 0 0 2.14E+07 1.25E+07 - - - 6.8525 0.9995 221125_WJC_METTL3_EV_vs_WT_F06.08629.08629.2 0.00125 20-Aug R.ADTQTYQPYNK.D sp|P84090|ERH_HUMAN 1 1327.6044 2.97 78775 8629 2 1327.605787 664.8095 Enhancer of rudimentary homolog OS=Homo sapiens OX=9606 GN=ERH PE=1 SV=1 5.88 1866.4 - 275438 - - - 1.0108 - 1.653 0.407 - 178.6 1 2 0 0.0013 11 0 0 0 1.01E+07 3.40E+06 - - - 3.4063 0.9987 221125_WJC_METTL3_EV_vs_WT_F06.08630.08630.2 0.00795 16-Aug K.EQELDTLKR.K sp|P11388|TOP2A_HUMAN 1 1130.5932 2.43 78776 8630 2 1130.594739 566.3039 DNA topoisomerase 2-alpha OS=Homo sapiens OX=9606 GN=TOP2A PE=1 SV=3 4.68 1866.6 - 263584 - - - 1.4037 - 1.481 0.321 - 246.9 1 2 0 0.0016 9 0 0 0 5.37E+06 2.21E+06 - - - 2.5476 0.9992 221125_WJC_METTL3_EV_vs_WT_F06.08631.08631.2 0.0057 22-Jul R.YLAEVAAGDDKK.G "sp|P63104|1433Z_HUMAN,tr|H0YB80|H0YB80_HUMAN,tr|E7EX29|E7EX29_HUMAN,tr|B7Z2E6|B7Z2E6_HUMAN,tr|B0AZS6|B0AZS6_HUMAN" 5 1278.6456 0.53 78777 8631 2 1278.646795 640.3301 14-3-3 protein zeta\delta OS=Homo sapiens OX=9606 GN=YWHAZ PE=1 SV=1 4.56 1866.7 - 187001 - - - 0.9487 - 1.477 0.369 - 137.4 1 2 0 0.0012 12 0 0 0 5.51E+06 1.04E+07 - - - 2.7922 0.9996 221125_WJC_METTL3_EV_vs_WT_F06.08632.08632.2 1.40E-05 26-Jul R.AALMESQGQQQEER.G "sp|Q14980|NUMA1_HUMAN,tr|A0A087WY61|A0A087WY61_HUMAN" 2 1603.726 1.4 78778 8632 2 1603.728625 802.8703 Nuclear mitotic apparatus protein 1 OS=Homo sapiens OX=9606 GN=NUMA1 PE=1 SV=2 4.25 1866.8 - 149974 - - - 1.6156 - 1.53 0.52 - 93 1 2 0 0.0026 14 0 0 0 1.26E+06 9.01E+05 - - - 3.9481 0.9998 221125_WJC_METTL3_EV_vs_WT_F06.08636.08636.2 0.000184 18-Sep R.QGSVPDYGQR.L "sp|O94761|RECQ4_HUMAN,tr|V9GYB6|V9GYB6_HUMAN" 2 1105.5152 0.84 78780 8636 2 1105.516861 553.7649 ATP-dependent DNA helicase Q4 OS=Homo sapiens OX=9606 GN=RECQL4 PE=1 SV=2 5.84 1867.4 - 789446 - - - 1.4699 - 1.988 0.521 - 307 1 2 0 0.0016 10 0 0 0 2.70E+07 3.23E+07 - - - 4.8066 0.9996 221125_WJC_METTL3_EV_vs_WT_F06.08637.08637.2 0.00042 18-Sep R.QGSVPDYGQR[166.11].L "sp|O94761|RECQ4_HUMAN,tr|V9GYB6|V9GYB6_HUMAN" 2 1115.5235 0.81 78781 8637 2 1115.525728 558.769 ATP-dependent DNA helicase Q4 OS=Homo sapiens OX=9606 GN=RECQL4 PE=1 SV=2 5.84 1867.5 - 1.05E+06 - - - 1.9919 - 2.003 0.425 - 281.8 1 2 0 0.0022 10 0 0 0 2.70E+07 3.31E+07 - - - 4.1183 0.9992 221125_WJC_METTL3_EV_vs_WT_F06.08641.08641.2 0.0105 20-Sep K.IDR[166.11]PEAISEER[166.11].L "sp|Q9Y6B6|SAR1B_HUMAN,tr|D6RD69|D6RD69_HUMAN,tr|D6R9R5|D6R9R5_HUMAN,tr|Q9H029|Q9H029_HUMAN" 4 1333.6741 1.11 78785 8641 2 1333.676513 667.8443 GTP-binding protein SAR1b OS=Homo sapiens OX=9606 GN=SAR1B PE=1 SV=1 4.41 1868 - 208368 - - - 1.822 - 1.987 0.32 - 131.4 1 2 0 0.0024 11 0 0 0 1.82E+08 1.65E+08 - - - 3.2612 0.9998 221125_WJC_METTL3_EV_vs_WT_F06.08649.08649.2 4.25E-05 20-Oct K.FC[160.03]DNSSAIQGK.E sp|O15067|PUR4_HUMAN 1 1225.5397 0.56 78791 8649 2 1225.54166 613.7771 Phosphoribosylformylglycinamidine synthase OS=Homo sapiens OX=9606 GN=PFAS PE=1 SV=4 5.83 1868.8 - 556956 - - - 1.5691 - 2.087 0.553 - 244.2 1 2 0 0.0019 11 0 0 0 1.09E+07 1.93E+07 - - - 5.1152 0.9915 221125_WJC_METTL3_EV_vs_WT_F06.08650.08650.3 0.00827 Sep-44 R.SAEEVEEIK[136.11]AEK[136.11].E sp|Q8WUA2|PPIL4_HUMAN 1 1376.7006 1.56 78792 8650 3 1376.702152 459.9075 Peptidyl-prolyl cis-trans isomerase-like 4 OS=Homo sapiens OX=9606 GN=PPIL4 PE=1 SV=1 4.32 1869 - 553988 - - - 1.1346 - 1.491 0.3 - 47.6 1 2 1 0.0016 12 0 0 0 2.39E+07 1.54E+07 - - - 2.9915 1 221125_WJC_METTL3_EV_vs_WT_F06.08652.08652.2 3.90E-06 24-Dec R.APGAEEDDSELQR[166.11].A "sp|Q53F19|NCBP3_HUMAN,tr|K7ELP6|K7ELP6_HUMAN" 2 1425.6247 1.71 78794 8652 2 1425.62424 713.8196 Nuclear cap-binding protein subunit 3 OS=Homo sapiens OX=9606 GN=NCBP3 PE=1 SV=2 3.83 1869.2 - 450423 - - - -0.3479 - 2.773 0.671 - 577.3 1 2 0 -0.0005 13 0 0 0 2.14E+07 1.25E+07 - - - 6.6145 0.9971 221125_WJC_METTL3_EV_vs_WT_F06.08653.08653.2 0.0458 20-Nov K.IDRPEAISEER.L "sp|Q9Y6B6|SAR1B_HUMAN,tr|D6RD69|D6RD69_HUMAN,tr|D6R9R5|D6R9R5_HUMAN,tr|Q9H029|Q9H029_HUMAN" 4 1313.6575 1.12 78795 8653 2 1313.661878 657.836 GTP-binding protein SAR1b OS=Homo sapiens OX=9606 GN=SAR1B PE=1 SV=1 4.41 1869.4 - 376408 - - - 3.2999 - 2.02 0.277 - 209.3 1 2 0 0.0043 11 0 0 0 1.82E+08 1.62E+08 - - - 2.9876 0.9988 221125_WJC_METTL3_EV_vs_WT_F06.08655.08655.2 0.376 22-Nov R.YLAEVAAGDDK[136.11]K[136.11].G "sp|P63104|1433Z_HUMAN,tr|H0YB80|H0YB80_HUMAN,tr|E7EX29|E7EX29_HUMAN,tr|B7Z2E6|B7Z2E6_HUMAN,tr|B0AZS6|B0AZS6_HUMAN" 5 1294.674 0.53 78797 8655 2 1294.676412 648.3443 14-3-3 protein zeta\delta OS=Homo sapiens OX=9606 GN=YWHAZ PE=1 SV=1 4.56 1869.6 - 256151 - - - 1.8769 - 1.883 0.304 - 330.4 1 2 0 0.0024 12 0 0 0 5.51E+06 1.04E+07 - - - 2.9508 1 221125_WJC_METTL3_EV_vs_WT_F06.08659.08659.2 8.22E-07 20-Dec K.FC[160.03]DNSSAIQGK[136.11].E sp|O15067|PUR4_HUMAN 1 1233.5539 0.57 78799 8659 2 1233.550572 617.7842 Phosphoribosylformylglycinamidine synthase OS=Homo sapiens OX=9606 GN=PFAS PE=1 SV=4 5.83 1870.2 - 1.35E+06 - - - -2.7279 - 2.337 0.609 - 387.4 1 2 0 -0.0034 11 0 0 0 1.09E+07 1.91E+07 - - - 5.8344 0.9708 221125_WJC_METTL3_EV_vs_WT_F06.08660.08660.3 6.39E-05 Oct-36 Y.RTLLEGEESR.M sp|P04264|K2C1_HUMAN 1 1188.6099 80.69 78800 8660 3 1188.611796 397.2106 "Keratin, type II cytoskeletal 1 OS=Homo sapiens OX=9606 GN=KRT1 PE=1 SV=6" 4.79 1870.2 - 1.24E+06 - - - 1.6246 - 1.946 0.372 - 174.8 1 1 0 0.0019 10 0 0 0 1.64E+08 2.03E+06 - - - 4.6313 0.9998 221125_WJC_METTL3_EV_vs_WT_F06.08662.08662.3 1.66E-06 15/52 R.ADAGHAGVSANMMK.K sp|Q9Y657|SPIN1_HUMAN 1 1358.6071 2.95 78802 8662 3 1358.610117 453.8763 Spindlin-1 OS=Homo sapiens OX=9606 GN=SPIN1 PE=1 SV=3 6.79 1870.4 - 863901 - - - 2.217 - 2.32 0.417 - 251 1 2 0 0.003 14 0 0 0 2.54E+07 8.61E+06 - - - 5.4248 0.9958 221125_WJC_METTL3_EV_vs_WT_F06.08663.08663.2 0.00557 16-Sep K.DHTQVVSLK.D sp|Q96EX1|SIM12_HUMAN 1 1025.5506 3.68 78803 8663 2 1025.554825 513.7826 Small integral membrane protein 12 OS=Homo sapiens OX=9606 GN=SMIM12 PE=1 SV=3 6.74 1870.5 - 755206 - - - 4.1597 - 1.931 0.315 - 300.4 1 2 0 0.0043 9 0 0 0 6.44E+07 1.75E+07 - - - 3.27 0.999 221125_WJC_METTL3_EV_vs_WT_F06.08666.08666.2 1.78 18-Dec R.KLDDTDPVPR.G "sp|O95721|SNP29_HUMAN,tr|C9JAF7|C9JAF7_HUMAN" 2 1154.5932 2 78806 8666 2 1154.596567 578.3039 Synaptosomal-associated protein 29 OS=Homo sapiens OX=9606 GN=SNAP29 PE=1 SV=1 4.43 1870.9 - 299501 - - - 2.9578 - 2.419 0.337 - 503.3 1 2 0 0.0034 10 0 0 0 9.58E+07 4.80E+07 - - - 3.9947 0.9947 221125_WJC_METTL3_EV_vs_WT_F06.08668.08668.2 0.0115 18-Jul R.KYPLPPPSGR.Y sp|Q9H0D6|XRN2_HUMAN 1 1110.6186 1.08 78808 8668 2 1110.621525 556.3166 5'-3' exoribonuclease 2 OS=Homo sapiens OX=9606 GN=XRN2 PE=1 SV=1 9.99 1871.1 - 486270 - - - 2.6526 - 1.209 0.333 - 157.1 1 2 0 0.0029 10 0 0 0 4.29E+06 3.95E+06 - - - 2.0294 1 221125_WJC_METTL3_EV_vs_WT_F06.08673.08673.2 9.55E-07 14/22 R.K[136.11]VVGDVAYDEAK[136.11].E "sp|P11586|C1TC_HUMAN,tr|F5H2F4|F5H2F4_HUMAN,tr|V9GZ78|V9GZ78_HUMAN,tr|V9GYY3|V9GYY3_HUMAN" 4 1308.6896 1.54 78811 8673 2 1308.691421 655.3521 "C-1-tetrahydrofolate synthase, cytoplasmic OS=Homo sapiens OX=9606 GN=MTHFD1 PE=1 SV=4" 4.56 1871.7 - 1.00E+06 - - - 1.367 - 2.894 0.581 - 523.4 1 2 0 0.0018 12 0 0 0 7.10E+07 4.61E+07 - - - 6.1277 0.9307 221125_WJC_METTL3_EV_vs_WT_F06.08674.08674.2 0.608 14-Oct A.RDLDELSR.Y "sp|P43243|MATR3_HUMAN,tr|A8MXP9|A8MXP9_HUMAN,tr|D6R991|D6R991_HUMAN,tr|A0A0R4J2E8|A0A0R4J2E8_HUMAN,tr|D6REM6|D6REM6_HUMAN" 5 1002.5094 2.14 78812 8674 2 1002.509379 502.262 Matrin-3 OS=Homo sapiens OX=9606 GN=MATR3 PE=1 SV=2 4.56 1871.8 - 857884 - - - -0.0439 - 1.827 0.179 - 277.3 1 1 0 0 8 0 0 0 1.32E+07 6.16E+06 - - - 2.1807 1 221125_WJC_METTL3_EV_vs_WT_F06.08675.08675.2 2.13E-07 14/22 K.VGGTSDVEVNEK[136.11].K "sp|P10809|CH60_HUMAN,tr|A0A7I2V2X6|A0A7I2V2X6_HUMAN,tr|A0A7I2YQK6|A0A7I2YQK6_HUMAN,tr|A0A7I2V599|A0A7I2V599_HUMAN" 4 1240.6027 0.9 78813 8675 2 1240.604902 621.3086 "60 kDa heat shock protein, mitochondrial OS=Homo sapiens OX=9606 GN=HSPD1 PE=1 SV=2" 4.14 1872 - 736916 - - - 1.8064 - 2.97 0.592 - 930.7 1 2 0 0.0022 12 0 0 0 1.59E+07 1.76E+07 - - - 6.277 1 221125_WJC_METTL3_EV_vs_WT_F06.08679.08679.2 7.93E-05 13/24 K.LEEANGNTQMVEK.L sp|O94906|PRP6_HUMAN 1 1461.677 4.34 78817 8679 2 1461.679373 731.8458 Pre-mRNA-processing factor 6 OS=Homo sapiens OX=9606 GN=PRPF6 PE=1 SV=1 4.25 1872.5 - 251933 - - - 1.6522 - 2.801 0.576 - 574.3 1 2 0 0.0024 13 0 0 0 1.09E+07 2.52E+06 - - - 5.938 0.9996 221125_WJC_METTL3_EV_vs_WT_F06.08680.08680.2 0.00228 22-Sep R.LVTQDTENELK[136.11]K[136.11].L "sp|P51692|STA5B_HUMAN,sp|P42229|STA5A_HUMAN,tr|A0A7I2YQY3|A0A7I2YQY3_HUMAN,tr|K7EIF9|K7EIF9_HUMAN,tr|K7EK35|K7EK35_HUMAN,tr|A0A7I2V380|A0A7I2V380_HUMAN,tr|A0A7I2YQF1|A0A7I2YQF1_HUMAN" 7 1432.7744 0.01 78818 8680 2 1432.776605 717.3945 Signal transducer and activator of transcription 5B OS=Homo sapiens OX=9606 GN=STAT5B PE=1 SV=2 4.68 1872.6 - 177447 - - - 1.5222 - 1.884 0.43 - 213.5 1 2 0 0.0022 12 0 0 0 6.29E+04 7.28E+06 - - - 3.8829 0.9616 221125_WJC_METTL3_EV_vs_WT_F06.08684.08684.2 1.51 16-May R.NIHSSDWPK[136.11].F "sp|Q9Y224|RTRAF_HUMAN,tr|G3V4C6|G3V4C6_HUMAN,tr|G3V4E7|G3V4E7_HUMAN" 3 1090.5287 1.68 78821 8684 2 1090.530955 546.2716 "RNA transcription, translation and transport factor protein OS=Homo sapiens OX=9606 GN=RTRAF PE=1 SV=1" 6.74 1873.1 - 290954 - - - 2.0605 - 1.062 0.146 - 77.4 1 2 0 0.0022 9 0 0 0 5.00E+06 2.98E+06 - - - 0.2927 0.9996 221125_WJC_METTL3_EV_vs_WT_F06.08687.08687.2 0.000192 18-Nov K.ETAEAYLGK[136.11]K[136.11].V "sp|P11021|BIP_HUMAN,tr|A0A7P0TB36|A0A7P0TB36_HUMAN,tr|A0A7P0TAI0|A0A7P0TAI0_HUMAN" 3 1124.6048 0.68 78824 8687 2 1124.60727 563.3097 Endoplasmic reticulum chaperone BiP OS=Homo sapiens OX=9606 GN=HSPA5 PE=1 SV=2 6.24 1873.4 - 781025 - - - 2.1608 - 1.953 0.457 - 622.8 1 2 0 0.0024 10 0 0 0 1.39E+07 2.03E+07 - - - 4.284 0.9979 221125_WJC_METTL3_EV_vs_WT_F06.08688.08688.2 0.00449 18-Nov K.R[166.11]FPGYDSESK[136.11].E "sp|P46777|RL5_HUMAN,tr|A0A2R8Y6J3|A0A2R8Y6J3_HUMAN" 2 1202.5687 0.58 78825 8688 2 1202.570505 602.2916 60S ribosomal protein L5 OS=Homo sapiens OX=9606 GN=RPL5 PE=1 SV=3 6.07 1873.5 - 684635 - - - 1.5242 - 2.016 0.164 - 406.8 1 2 0 0.0018 10 0 0 0 5.40E+07 9.25E+07 - - - 2.2088 0.9881 221125_WJC_METTL3_EV_vs_WT_F06.08690.08690.3 0.341 Sep-36 R.K[136.11]LDDTDPVPR[166.11].G "sp|O95721|SNP29_HUMAN,tr|C9JAF7|C9JAF7_HUMAN" 2 1172.6156 1.61 78827 8690 3 1172.615736 391.8792 Synaptosomal-associated protein 29 OS=Homo sapiens OX=9606 GN=SNAP29 PE=1 SV=1 4.43 1873.7 - 436039 - - - 0.0972 - 1.683 0.147 - 139.8 1 2 0 0.0001 10 0 0 0 1.42E+08 8.81E+07 - - - 1.6992 0.9999 221125_WJC_METTL3_EV_vs_WT_F06.08691.08691.2 3.38E-05 24-Nov K.LEEANGNTQMVEK[136.11].L sp|O94906|PRP6_HUMAN 1 1469.6912 4.34 78828 8691 2 1469.692012 735.8529 Pre-mRNA-processing factor 6 OS=Homo sapiens OX=9606 GN=PRPF6 PE=1 SV=1 4.25 1873.8 - 193936 - - - 0.5811 - 2.491 0.571 - 355.6 1 2 0 0.0009 13 0 0 0 1.09E+07 2.52E+06 - - - 5.6006 0.9999 221125_WJC_METTL3_EV_vs_WT_F06.08695.08695.2 9.67E-06 20-Dec K.QTYSTEPNNLK[136.11].A "sp|P46779|RL28_HUMAN,tr|H0YMF4|H0YMF4_HUMAN,tr|H0YLP6|H0YLP6_HUMAN,tr|H0YKD8|H0YKD8_HUMAN" 4 1301.6343 0.93 78830 8695 2 1301.634685 651.8244 60S ribosomal protein L28 OS=Homo sapiens OX=9606 GN=RPL28 PE=1 SV=3 6 1874.3 - 3.29E+06 - - - 0.2996 - 2.18 0.57 - 427.2 1 2 0 0.0004 11 0 0 0 1.76E+08 1.90E+08 - - - 5.3592 0.9942 221125_WJC_METTL3_EV_vs_WT_F06.08696.08696.2 5.33E-08 22-Nov A.SSPVIC[160.03]AGGQDR.C sp|Q15365|PCBP1_HUMAN 1 1245.5772 0.65 78831 8696 2 1245.57653 623.7959 Poly(rC)-binding protein 1 OS=Homo sapiens OX=9606 GN=PCBP1 PE=1 SV=2 5.55 1874.4 - 402710 - - - -0.5259 - 2.253 0.568 - 496.7 1 1 0 -0.0007 12 0 0 0 9.71E+06 1.49E+07 - - - 5.3732 1 221125_WJC_METTL3_EV_vs_WT_F06.08699.08699.2 2.01E-05 13/22 K.VGGTSDVEVNEK.K "sp|P10809|CH60_HUMAN,tr|A0A7I2V2X6|A0A7I2V2X6_HUMAN,tr|A0A7I2YQK6|A0A7I2YQK6_HUMAN,tr|A0A7I2V599|A0A7I2V599_HUMAN" 4 1232.5885 0.9 78832 8699 2 1232.587987 617.3015 "60 kDa heat shock protein, mitochondrial OS=Homo sapiens OX=9606 GN=HSPD1 PE=1 SV=2" 4.14 1874.8 - 1.15E+06 - - - -0.3846 - 2.704 0.604 - 678.4 1 2 0 -0.0005 12 0 0 0 1.59E+07 1.76E+07 - - - 6.1193 0.9985 221125_WJC_METTL3_EV_vs_WT_F06.08701.08701.2 0.276 14-Nov K.RFEGLTQR.G sp|Q9Y2H1|ST38L_HUMAN 1 1005.5356 2.27 78833 8701 2 1005.53654 503.7751 Serine\threonine-protein kinase 38-like OS=Homo sapiens OX=9606 GN=STK38L PE=1 SV=3 9.6 1875.1 - 912386 - - - 0.9567 - 1.841 0.187 - 299.4 1 2 0 0.001 8 0 0 0 1.39E+08 6.13E+07 - - - 2.2625 0.9998 221125_WJC_METTL3_EV_vs_WT_F06.08705.08705.3 0.0303 Oct-40 K.IDRPEAISEER[166.11].L "sp|Q9Y6B6|SAR1B_HUMAN,tr|D6RD69|D6RD69_HUMAN,tr|D6R9R5|D6R9R5_HUMAN,tr|Q9H029|Q9H029_HUMAN" 4 1323.6658 - 78837 8705 3 1323.66614 442.2292 GTP-binding protein SAR1b OS=Homo sapiens OX=9606 GN=SAR1B PE=1 SV=1 4.41 1875.5 - 348783 - - - 0.247 - 2.176 0.341 - 207.7 1 2 0 0.0003 11 0 0 0 - - - - - 4.5504 0.9369 221125_WJC_METTL3_EV_vs_WT_F06.08707.08707.2 0.00849 18-Sep R.SAK[136.11]EEIAEYR[166.11].R "sp|P07197|NFM_HUMAN,tr|E7ESP9|E7ESP9_HUMAN,tr|E7EMV2|E7EMV2_HUMAN" 3 1212.6105 1.14 78839 8707 2 1212.615767 607.3125 Neurofilament medium polypeptide OS=Homo sapiens OX=9606 GN=NEFM PE=1 SV=3 4.78 1875.8 - 236794 - - - 4.313 - 1.498 0.387 - 202.3 1 2 1 0.0052 10 0 0 0 1.01E+07 8.90E+06 - - - 3.0258 0.9997 221125_WJC_METTL3_EV_vs_WT_F06.08708.08708.2 0.0041 22-Nov K.THVMLGAETEEK[136.11].L "sp|Q9NQA3|WASH6_HUMAN,sp|A8K0Z3|WASH1_HUMAN,sp|A8MWX3|WASH4_HUMAN,sp|C4AMC7|WASH3_HUMAN,sp|Q6VEQ5|WASH2_HUMAN,tr|A0A7I2YQU6|A0A7I2YQU6_HUMAN" 6 1351.6533 0.9 78840 8708 2 1351.654302 676.8339 WAS protein family homolog 6 OS=Homo sapiens OX=9606 GN=WASH6P PE=1 SV=3 4.75 1875.9 - 197395 - - - 0.7295 - 1.864 0.405 - 235.9 1 2 0 0.001 12 0 0 0 3.69E+06 4.09E+06 - - - 3.6705 0.9998 221125_WJC_METTL3_EV_vs_WT_F06.08712.08712.2 0.000595 20-Aug K.QTYSTEPNNLK.A "sp|P46779|RL28_HUMAN,tr|H0YMF4|H0YMF4_HUMAN,tr|H0YLP6|H0YLP6_HUMAN,tr|H0YKD8|H0YKD8_HUMAN" 4 1293.6201 0.93 78842 8712 2 1293.618865 647.8173 60S ribosomal protein L28 OS=Homo sapiens OX=9606 GN=RPL28 PE=1 SV=3 6 1876.4 - 6.74E+06 - - - -0.9508 - 1.657 0.507 - 146.4 1 2 0 -0.0012 11 0 0 0 1.76E+08 1.90E+08 - - - 4.1515 0.9996 221125_WJC_METTL3_EV_vs_WT_F06.08717.08717.2 0.0126 12-Oct K.K[136.11]FDDFQK[136.11].D "sp|Q13813|SPTN1_HUMAN,tr|A0A0D9SF54|A0A0D9SF54_HUMAN,tr|A0A0D9SGF6|A0A0D9SGF6_HUMAN" 3 942.4782 1.63 78847 8717 2 942.477224 472.2464 "Spectrin alpha chain, non-erythrocytic 1 OS=Homo sapiens OX=9606 GN=SPTAN1 PE=1 SV=3" 5.96 1876.7 - 1.38E+06 - - - -1.0165 - 1.578 0.409 - 321.7 1 2 0 -0.001 7 0 0 0 3.82E+07 2.35E+07 - - - 3.5069 0.9996 221125_WJC_METTL3_EV_vs_WT_F06.08720.08720.2 0.00241 20-Dec R.QSGPGAPNLDR.F "sp|O15027|SC16A_HUMAN,tr|A0A3F2YNX0|A0A3F2YNX0_HUMAN,tr|A0A3F2YNZ0|A0A3F2YNZ0_HUMAN,tr|F1T0I1|F1T0I1_HUMAN" 4 1110.5418 1.07 78850 8720 2 1110.541044 556.2782 Protein transport protein Sec16A OS=Homo sapiens OX=9606 GN=SEC16A PE=1 SV=4 5.84 1877.1 - 819638 - - - -0.6672 - 1.923 0.359 - 508.8 1 2 0 -0.0007 11 0 0 0 2.24E+07 2.09E+07 - - - 3.4613 0.9296 221125_WJC_METTL3_EV_vs_WT_F06.08724.08724.3 0.678 Jul-32 R.YKTQYEELK.A sp|P12270|TPR_HUMAN 1 1200.6027 1.51 78852 8724 3 1200.601321 401.2082 Nucleoprotein TPR OS=Homo sapiens OX=9606 GN=TPR PE=1 SV=3 6.14 1877.5 - 2.20E+06 - - - -1.1103 - 1.386 0.194 - 44.6 2 2 1 -0.0013 9 0 0 0 3.99E+07 2.64E+07 - - - 1.547 0.9999 221125_WJC_METTL3_EV_vs_WT_F06.08726.08726.2 0.0167 13/20 K.STESLQANVQR.L "sp|P26373|RL13_HUMAN,tr|J3QSB4|J3QSB4_HUMAN" 2 1231.6157 1.07 78854 8726 2 1231.614781 616.8151 60S ribosomal protein L13 OS=Homo sapiens OX=9606 GN=RPL13 PE=1 SV=4 5.72 1877.6 - 2.28E+06 - - - -0.7291 - 2.649 0.433 - 914.7 1 2 0 -0.0009 11 0 0 0 4.04E+08 3.76E+08 - - - 4.8742 0.9999 221125_WJC_METTL3_EV_vs_WT_F06.08727.08727.2 0.0013 16-Oct R.DASNWSTDK[136.11].L "sp|O95433|AHSA1_HUMAN,tr|G3V3W9|G3V3W9_HUMAN" 2 1030.4447 1.33 78855 8727 2 1030.444386 516.2296 Activator of 90 kDa heat shock protein ATPase homolog 1 OS=Homo sapiens OX=9606 GN=AHSA1 PE=1 SV=1 4.21 1877.7 - 2.12E+06 - - - -0.3086 - 2.107 0.509 - 387.5 1 2 0 -0.0003 9 0 0 0 8.53E+07 6.41E+07 - - - 4.9565 0.9977 221125_WJC_METTL3_EV_vs_WT_F06.08731.08731.2 0.0631 18-Oct R.TDAISEEKLR.E "sp|Q9NR31|SAR1A_HUMAN,tr|H0Y5E8|H0Y5E8_HUMAN" 2 1160.6037 0.93 78859 8731 2 1160.603732 581.3091 GTP-binding protein SAR1a OS=Homo sapiens OX=9606 GN=SAR1A PE=1 SV=1 4.68 1878.2 - 756758 - - - 0.0129 - 2.288 0.368 - 400.9 1 2 1 0 10 0 0 0 2.30E+07 2.46E+07 - - - 4.0693 0.9998 221125_WJC_METTL3_EV_vs_WT_F06.08738.08738.2 0.000647 16-Sep R.DASNWSTDK.L "sp|O95433|AHSA1_HUMAN,tr|G3V3W9|G3V3W9_HUMAN" 2 1022.4305 1.33 78864 8738 2 1022.429981 512.2225 Activator of 90 kDa heat shock protein ATPase homolog 1 OS=Homo sapiens OX=9606 GN=AHSA1 PE=1 SV=1 4.21 1878.9 - 3.05E+06 - - - -0.5115 - 1.955 0.449 - 287.7 1 2 0 -0.0005 9 0 0 0 8.54E+07 6.41E+07 - - - 4.2966 1 221125_WJC_METTL3_EV_vs_WT_F06.08739.08739.2 1.00E-06 14/16 K.HEQEYMEVR.E "sp|Q15363|TMED2_HUMAN,tr|F5GX39|F5GX39_HUMAN,tr|E7EQ72|E7EQ72_HUMAN" 3 1219.5292 1.32 78865 8739 2 1219.528383 610.7719 Transmembrane emp24 domain-containing protein 2 OS=Homo sapiens OX=9606 GN=TMED2 PE=1 SV=1 4.75 1879 - 2.40E+06 - - - -0.647 - 2.424 0.611 - 678.6 1 2 0 -0.0008 9 0 0 0 9.68E+07 7.31E+07 - - - 6.1152 0.9998 221125_WJC_METTL3_EV_vs_WT_F06.08740.08740.2 5.65E-06 20-Dec R.QSGPGAPNLDR[166.11].F "sp|O15027|SC16A_HUMAN,tr|A0A3F2YNX0|A0A3F2YNX0_HUMAN,tr|A0A3F2YNZ0|A0A3F2YNZ0_HUMAN,tr|F1T0I1|F1T0I1_HUMAN" 4 1120.5501 1.11 78866 8740 2 1120.548816 561.2823 Protein transport protein Sec16A OS=Homo sapiens OX=9606 GN=SEC16A PE=1 SV=4 5.84 1879.1 - 1.63E+06 - - - -1.1057 - 1.9 0.485 - 520.1 1 2 0 -0.0012 11 0 0 0 2.37E+07 2.14E+07 - - - 4.3592 0.9994 221125_WJC_METTL3_EV_vs_WT_F06.08748.08748.2 0.00405 18-Sep R.QTTITSHFAK[136.11].G "sp|P26358|DNMT1_HUMAN,tr|A0A7I2V5D0|A0A7I2V5D0_HUMAN,tr|K7EJL0|K7EJL0_HUMAN,tr|A0A7I2V5F1|A0A7I2V5F1_HUMAN,tr|A0A7I2V5F6|A0A7I2V5F6_HUMAN,tr|A0A7I2V2G5|A0A7I2V2G5_HUMAN,tr|A0A7I2YQA8|A0A7I2YQA8_HUMAN,tr|A0A7I2YQQ0|A0A7I2YQQ0_HUMAN,tr|A0A7I2V311|A0A7I2V311_HUMAN,tr|K7ERQ1|K7ERQ1_HUMAN,tr|K7ENQ6|K7ENQ6_HUMAN,tr|A0A7I2V490|A0A7I2V490_HUMAN,tr|K7ELB1|K7ELB1_HUMAN" 13 1140.6019 0.58 78874 8748 2 1140.603599 571.3082 DNA (cytosine-5)-methyltransferase 1 OS=Homo sapiens OX=9606 GN=DNMT1 PE=1 SV=2 8.76 1880.1 - 557617 - - - 1.5132 - 1.771 0.378 - 232.9 1 2 0 0.0017 10 0 0 0 3.80E+06 6.52E+06 - - - 3.4277 1 221125_WJC_METTL3_EV_vs_WT_F06.08752.08752.3 1.37E-06 Sep-32 K.HEQEYMEVR.E "sp|Q15363|TMED2_HUMAN,tr|F5GX39|F5GX39_HUMAN,tr|E7EQ72|E7EQ72_HUMAN" 3 1219.5292 1.2 78876 8752 3 1219.527735 407.517 Transmembrane emp24 domain-containing protein 2 OS=Homo sapiens OX=9606 GN=TMED2 PE=1 SV=1 4.75 1880.6 - 3.40E+06 - - - -1.1783 - 2.038 0.584 - 148.6 1 2 0 -0.0014 9 0 0 0 6.27E+07 5.24E+07 - - - 7.1964 0.9948 221125_WJC_METTL3_EV_vs_WT_F06.08753.08753.2 0.00825 16-Oct K.VSELK[136.11]EELK[136.11].K "sp|Q00839|HNRPU_HUMAN,tr|A0A1W2PPS1|A0A1W2PPS1_HUMAN,tr|A0A1X7SBS1|A0A1X7SBS1_HUMAN" 3 1089.6252 0.69 78877 8753 2 1089.623524 545.8199 Heterogeneous nuclear ribonucleoprotein U OS=Homo sapiens OX=9606 GN=HNRNPU PE=1 SV=6 4.79 1880.6 - 2.68E+06 - - - -1.5758 - 1.928 0.364 - 498 1 2 1 -0.0017 9 0 0 0 4.23E+07 6.10E+07 - - - 3.6282 0.9973 221125_WJC_METTL3_EV_vs_WT_F06.08754.08754.2 0.111 14-Sep K.HFELGGDK.K "sp|P83881|RL36A_HUMAN,sp|Q969Q0|RL36L_HUMAN,tr|H0Y5B4|H0Y5B4_HUMAN,tr|J3KQN4|J3KQN4_HUMAN,tr|R4GN19|R4GN19_HUMAN,tr|H7BZ11|H7BZ11_HUMAN" 6 901.4294 0.91 78878 8754 2 901.427275 451.722 60S ribosomal protein L36a OS=Homo sapiens OX=9606 GN=RPL36A PE=1 SV=2 5.32 1880.7 - 8.82E+06 - - - -2.3363 - 1.477 0.294 - 210.6 1 2 0 -0.0021 8 0 0 0 7.61E+07 8.35E+07 - - - 2.3881 0.9999 221125_WJC_METTL3_EV_vs_WT_F06.08755.08755.3 1.20E-05 Sep-32 K.HEQEYMEVR[166.11].E "sp|Q15363|TMED2_HUMAN,tr|F5GX39|F5GX39_HUMAN,tr|E7EQ72|E7EQ72_HUMAN" 3 1229.5374 1.21 78879 8755 3 1229.536093 410.8531 Transmembrane emp24 domain-containing protein 2 OS=Homo sapiens OX=9606 GN=TMED2 PE=1 SV=1 4.75 1880.7 - 3.32E+06 - - - -1.0972 - 1.791 0.469 - 146.4 1 2 0 -0.0013 9 0 0 0 6.27E+07 5.19E+07 - - - 5.5249 0.9984 221125_WJC_METTL3_EV_vs_WT_F06.08764.08764.3 0.0698 Oct-36 R.GFVQVDDGR[166.11]K[136.11].L sp|P54136|SYRC_HUMAN 1 1137.5897 0.001 78886 8764 3 1137.589853 380.2039 "Arginine--tRNA ligase, cytoplasmic OS=Homo sapiens OX=9606 GN=RARS1 PE=1 SV=2" 5.96 1881.6 - 1.70E+06 - - - 0.0976 - 1.719 0.255 - 111.1 1 2 0 0.0001 10 0 0 0 0.00E+00 7.76E+07 - - - 2.9651 1 221125_WJC_METTL3_EV_vs_WT_F06.08765.08765.2 9.08E-10 16/30 K.GTGGASAEGGPTGLAH.G sp|Q96F45|ZN503_HUMAN 1 1338.6164 - 78887 8765 2 1338.614608 670.3155 Zinc finger protein 503 OS=Homo sapiens OX=9606 GN=ZNF503 PE=1 SV=1 5.24 1881.7 - 1.03E+06 - - - -1.3439 - 2.938 0.631 - 616.9 1 1 0 -0.0018 16 0 0 0 - - - - - 6.3506 0.9948 221125_WJC_METTL3_EV_vs_WT_F06.08769.08769.2 0.0422 18-Sep R.TDAISEEK[136.11]LR[166.11].E "sp|Q9NR31|SAR1A_HUMAN,tr|H0Y5E8|H0Y5E8_HUMAN" 2 1178.6262 0.97 78889 8769 2 1178.626711 590.3204 GTP-binding protein SAR1a OS=Homo sapiens OX=9606 GN=SAR1A PE=1 SV=1 4.68 1882.2 - 1.09E+06 - - - 0.4446 - 2.033 0.29 - 346.2 1 2 1 0.0005 10 0 0 0 2.30E+07 2.38E+07 - - - 3.1632 0.9996 221125_WJC_METTL3_EV_vs_WT_F06.08771.08771.3 0.00325 Oct-36 K.LNVEAVNTHR.D "sp|O60825|F262_HUMAN,sp|P16118|F261_HUMAN,tr|I1Z9G3|I1Z9G3_HUMAN,tr|Q4VBA9|Q4VBA9_HUMAN" 4 1151.6047 1.19 78891 8771 3 1151.603154 384.8755 "6-phosphofructo-2-kinase\fructose-2,6-bisphosphatase 2 OS=Homo sapiens OX=9606 GN=PFKFB2 PE=1 SV=2" 6.75 1882.3 - 5.40E+06 - - - -1.3598 - 2.081 0.312 - 127.7 1 2 0 -0.0016 10 0 0 0 9.81E+07 8.27E+07 - - - 4.1583 0.9997 221125_WJC_METTL3_EV_vs_WT_F06.08772.08772.2 0.000254 16-Sep K.DHENIVIAK[136.11].M "sp|P07237|PDIA1_HUMAN,tr|A0A7P0TA97|A0A7P0TA97_HUMAN,tr|A0A7P0T8C0|A0A7P0T8C0_HUMAN,tr|H7BZ94|H7BZ94_HUMAN,tr|B3KTQ9|B3KTQ9_HUMAN,tr|A0A7P0TA71|A0A7P0TA71_HUMAN,tr|I3L4M2|I3L4M2_HUMAN,tr|A0A7P0T9K9|A0A7P0T9K9_HUMAN,tr|H0Y3Z3|H0Y3Z3_HUMAN,tr|A0A7P0TA35|A0A7P0TA35_HUMAN,tr|A0A7P0TB26|A0A7P0TB26_HUMAN,tr|A0A7P0T9U6|A0A7P0T9U6_HUMAN,tr|I3L0S0|I3L0S0_HUMAN,tr|I3L3P5|I3L3P5_HUMAN,tr|A0A7P0T8J3|A0A7P0T8J3_HUMAN,tr|A0A7P0T8X1|A0A7P0T8X1_HUMAN" 16 1045.5648 0.15 78892 8772 2 1045.564574 523.7897 Protein disulfide-isomerase OS=Homo sapiens OX=9606 GN=P4HB PE=1 SV=3 5.32 1882.4 - 839272 - - - -0.1769 - 1.687 0.437 - 306.5 1 2 0 -0.0002 9 0 0 0 6.46E+07 4.18E+08 - - - 3.7816 1 221125_WJC_METTL3_EV_vs_WT_F06.08773.08773.2 5.67E-09 16/28 R.GGPGGPGGPGGPMGR.M "sp|Q01844|EWS_HUMAN,tr|B0QYK0|B0QYK0_HUMAN,tr|H7BY36|H7BY36_HUMAN,tr|A0A0D9SFL3|A0A0D9SFL3_HUMAN,tr|C9JGE3|C9JGE3_HUMAN" 5 1206.5564 1.09 78893 8773 2 1206.55361 604.2855 RNA-binding protein EWS OS=Homo sapiens OX=9606 GN=EWSR1 PE=1 SV=1 9.75 1882.6 - 731617 - - - -2.3041 - 2.913 0.662 - 979.5 1 2 0 -0.0028 15 0 0 0 1.73E+07 1.59E+07 - - - 6.5583 0.9773 221125_WJC_METTL3_EV_vs_WT_F06.08774.08774.2 0.349 22-Jul R.GFGSDQSENVDR[166.11].G "sp|Q9UII2|ATIF1_HUMAN,tr|A0A0B4J230|A0A0B4J230_HUMAN" 2 1319.5617 2.32 78894 8774 2 1319.564504 660.7881 "ATPase inhibitor, mitochondrial OS=Homo sapiens OX=9606 GN=ATP5IF1 PE=1 SV=1" 4.03 1882.7 - 597331 - - - 2.0931 - 1.158 0.168 - 125 1 2 0 0.0028 12 0 0 0 1.89E+07 8.14E+06 - - - 0.667 0.9526 221125_WJC_METTL3_EV_vs_WT_F06.08785.08785.2 3.24 14-Jun R.LSQDAYR[166.11]R[166.11].N "sp|A6NI72|NCF1B_HUMAN,sp|P14598|NCF1_HUMAN,sp|A8MVU1|NCF1C_HUMAN" 3 1027.5314 0.5 78901 8785 2 1027.530364 514.773 Putative neutrophil cytosol factor 1B OS=Homo sapiens OX=9606 GN=NCF1B PE=5 SV=2 8.75 1884.1 - 2.71E+06 - - - -0.9907 - 1.156 0.031 - 136.9 1 2 0 -0.001 8 0 0 0 2.26E+07 4.51E+07 - - - -0.2931 0.9508 221125_WJC_METTL3_EV_vs_WT_F06.08786.08786.3 0.0498 Oct-36 K.LNVEAVNTHR[166.11].D "sp|O60825|F262_HUMAN,sp|P16118|F261_HUMAN,tr|I1Z9G3|I1Z9G3_HUMAN,tr|Q4VBA9|Q4VBA9_HUMAN" 4 1161.613 1.19 78902 8786 3 1161.609988 388.2116 "6-phosphofructo-2-kinase\fructose-2,6-bisphosphatase 2 OS=Homo sapiens OX=9606 GN=PFKFB2 PE=1 SV=2" 6.75 1884.1 - 3.54E+06 - - - -2.5843 - 2.115 0.064 - 110.3 1 2 0 -0.003 10 0 0 0 9.83E+07 8.27E+07 - - - 1.4403 0.9999 221125_WJC_METTL3_EV_vs_WT_F06.08787.08787.2 0.000163 16-Nov K.DHENIVIAK.M "sp|P07237|PDIA1_HUMAN,tr|A0A7P0TA97|A0A7P0TA97_HUMAN,tr|A0A7P0T8C0|A0A7P0T8C0_HUMAN,tr|H7BZ94|H7BZ94_HUMAN,tr|B3KTQ9|B3KTQ9_HUMAN,tr|A0A7P0TA71|A0A7P0TA71_HUMAN,tr|I3L4M2|I3L4M2_HUMAN,tr|A0A7P0T9K9|A0A7P0T9K9_HUMAN,tr|H0Y3Z3|H0Y3Z3_HUMAN,tr|A0A7P0TA35|A0A7P0TA35_HUMAN,tr|A0A7P0TB26|A0A7P0TB26_HUMAN,tr|A0A7P0T9U6|A0A7P0T9U6_HUMAN,tr|I3L0S0|I3L0S0_HUMAN,tr|I3L3P5|I3L3P5_HUMAN,tr|A0A7P0T8J3|A0A7P0T8J3_HUMAN,tr|A0A7P0T8X1|A0A7P0T8X1_HUMAN" 16 1037.5506 0.37 78903 8787 2 1037.550027 519.7826 Protein disulfide-isomerase OS=Homo sapiens OX=9606 GN=P4HB PE=1 SV=3 5.32 1884.2 - 2.22E+06 - - - -0.5127 - 2.198 0.477 - 237.7 1 2 0 -0.0005 9 0 0 0 5.05E+07 1.36E+08 - - - 4.8424 0.9999 221125_WJC_METTL3_EV_vs_WT_F06.08789.08789.2 2.79E-08 14/26 R.SYAASASAAPAEPR.Y sp|P20719|HXA5_HUMAN 1 1347.6419 1.46 78905 8789 2 1347.641337 674.8282 Homeobox protein Hox-A5 OS=Homo sapiens OX=9606 GN=HOXA5 PE=1 SV=2 5.72 1884.4 - 1.06E+06 - - - -0.4126 - 2.175 0.586 - 360.6 1 2 0 -0.0006 14 0 0 0 3.56E+07 2.44E+07 - - - 5.3189 0.9989 221125_WJC_METTL3_EV_vs_WT_F06.08794.08794.2 0.201 18-Jun R.GPLPLSSQHR.G "sp|P43243|MATR3_HUMAN,tr|A8MXP9|A8MXP9_HUMAN,tr|D6R991|D6R991_HUMAN,tr|A0A0R4J2E8|A0A0R4J2E8_HUMAN,tr|D6R8Z5|D6R8Z5_HUMAN,tr|D6REM6|D6REM6_HUMAN" 6 1090.5883 2.08 78908 8794 2 1090.58763 546.3014 Matrin-3 OS=Homo sapiens OX=9606 GN=MATR3 PE=1 SV=2 9.76 1885 - 4.79E+06 - - - -0.6529 - 1.504 0.289 - 113 1 2 0 -0.0007 10 0 0 0 1.90E+08 9.14E+07 - - - 2.3145 0.9996 221125_WJC_METTL3_EV_vs_WT_F06.08796.08796.3 3.87E-05 15/40 K.DREVAEGGLPR.A "sp|Q9BUA3|SPNDC_HUMAN,tr|H0YGK9|H0YGK9_HUMAN,tr|H0YGY5|H0YGY5_HUMAN" 3 1197.6102 2.6 78910 8796 3 1197.608124 400.2107 Spindlin interactor and repressor of chromatin-binding protein OS=Homo sapiens OX=9606 GN=SPINDOC PE=1 SV=3 4.68 1885.1 - 1.62E+06 - - - -1.7326 - 2.759 0.384 - 296.1 1 2 1 -0.0021 11 0 0 0 1.16E+08 4.44E+07 - - - 5.7037 0.9998 221125_WJC_METTL3_EV_vs_WT_F06.08797.08797.2 0.000831 18-Sep R.GFVQVDDGR[166.11]K[136.11].L sp|P54136|SYRC_HUMAN 1 1137.5897 0.8 78911 8797 2 1137.590101 569.8021 "Arginine--tRNA ligase, cytoplasmic OS=Homo sapiens OX=9606 GN=RARS1 PE=1 SV=2" 5.96 1885.2 - 1.32E+06 - - - 0.3156 - 1.844 0.433 - 342.3 1 2 0 0.0004 10 0 0 0 1.75E+07 2.19E+07 - - - 3.9471 1 221125_WJC_METTL3_EV_vs_WT_F06.08798.08798.2 2.22E-08 13/26 R.SYAASASAAPAEPR[166.11].Y sp|P20719|HXA5_HUMAN 1 1357.6502 1.48 78912 8798 2 1357.650251 679.8324 Homeobox protein Hox-A5 OS=Homo sapiens OX=9606 GN=HOXA5 PE=1 SV=2 5.72 1885.4 - 1.14E+06 - - - 0.0648 - 2.866 0.62 - 749.1 1 2 0 0.0001 14 0 0 0 3.56E+07 2.40E+07 - - - 6.2625 0.9998 221125_WJC_METTL3_EV_vs_WT_F06.08803.08803.2 9.87E-05 18-Sep R.GFVQVDDGRK.L sp|P54136|SYRC_HUMAN 1 1119.5673 0.81 78915 8803 2 1119.566777 560.7909 "Arginine--tRNA ligase, cytoplasmic OS=Homo sapiens OX=9606 GN=RARS1 PE=1 SV=2" 5.96 1886.1 - 1.06E+06 - - - -0.4421 - 1.908 0.418 - 371.4 1 2 0 -0.0005 10 0 0 0 1.75E+07 2.16E+07 - - - 3.9315 0.8967 221125_WJC_METTL3_EV_vs_WT_F06.08806.08806.3 0.148 Aug-40 K.SYYK[136.11]PDSPEYK[136.11].A "sp|Q86U86|PB1_HUMAN,tr|H0Y5B5|H0Y5B5_HUMAN,tr|E7EVG2|E7EVG2_HUMAN,tr|C9JPI5|C9JPI5_HUMAN,tr|C9JQF1|C9JQF1_HUMAN" 5 1391.658 1.53 78918 8806 3 1391.654519 464.8933 Protein polybromo-1 OS=Homo sapiens OX=9606 GN=PBRM1 PE=1 SV=1 5.79 1886.3 - 904566 - - - -2.4992 - 1.087 0.195 - 67.6 1 2 0 -0.0035 11 0 0 0 6.19E+07 4.04E+07 - - - 0.9501 0.9999 221125_WJC_METTL3_EV_vs_WT_F06.08807.08807.2 7.74E-08 13/20 R.K[136.11]VVAEVYDQER[166.11].F "sp|Q9UHX1|PUF60_HUMAN,tr|A0A0J9YYL3|A0A0J9YYL3_HUMAN,tr|A0A0J9YXX5|A0A0J9YXX5_HUMAN,tr|A0A0J9YXJ8|A0A0J9YXJ8_HUMAN,tr|A0A0J9YVP6|A0A0J9YVP6_HUMAN" 5 1352.7055 2.42 78919 8807 2 1352.705501 677.36 Poly(U)-binding-splicing factor PUF60 OS=Homo sapiens OX=9606 GN=PUF60 PE=1 SV=1 4.68 1886.5 - 702427 - - - 0.0007 - 2.158 0.55 - 627.1 1 2 0 0 11 0 0 0 8.30E+07 3.43E+07 - - - 5.1841 0.9999 221125_WJC_METTL3_EV_vs_WT_F06.08809.08809.2 0.00105 14/22 R.AVAEQVLHSQSR.H sp|Q01804|OTUD4_HUMAN 1 1323.6895 12.18 78921 8809 2 1323.688334 662.852 OTU domain-containing protein 4 OS=Homo sapiens OX=9606 GN=OTUD4 PE=1 SV=4 6.79 1886.7 - 448319 - - - -0.8899 - 2.746 0.455 - 606 1 2 0 -0.0012 12 0 0 0 6.62E+06 5.44E+05 - - - 5.0591 1 221125_WJC_METTL3_EV_vs_WT_F06.08813.08813.3 2.91E-05 13/44 R.LNQSPSLAPVK[136.11]R[166.11].T "sp|Q9H2P0|ADNP_HUMAN,tr|A0A2R8Y6X0|A0A2R8Y6X0_HUMAN,tr|A0A669KBJ7|A0A669KBJ7_HUMAN" 3 1326.7739 1.44 78923 8813 3 1326.773171 443.2652 Activity-dependent neuroprotector homeobox protein OS=Homo sapiens OX=9606 GN=ADNP PE=1 SV=1 11 1887.3 - 2.47E+06 - - - -0.5148 - 2.846 0.449 - 307.5 1 2 0 -0.0007 12 0 0 0 7.58E+07 5.25E+07 - - - 6.4448 0.9999 221125_WJC_METTL3_EV_vs_WT_F06.08814.08814.3 0.00117 13/40 R.K[136.11]VVAEVYDQER[166.11].F "sp|Q9UHX1|PUF60_HUMAN,tr|A0A0J9YYL3|A0A0J9YYL3_HUMAN,tr|A0A0J9YXX5|A0A0J9YXX5_HUMAN,tr|A0A0J9YXJ8|A0A0J9YXJ8_HUMAN,tr|A0A0J9YVP6|A0A0J9YVP6_HUMAN" 5 1352.7055 7.67 78924 8814 3 1352.704945 451.9091 Poly(U)-binding-splicing factor PUF60 OS=Homo sapiens OX=9606 GN=PUF60 PE=1 SV=1 4.68 1887.3 - 2.42E+06 - - - -0.4103 - 1.951 0.437 - 248.7 1 2 0 -0.0006 11 0 0 0 5.01E+08 6.54E+07 - - - 5.3106 0.9998 221125_WJC_METTL3_EV_vs_WT_F06.08815.08815.2 0.00242 18-Dec K.RFPGYDSESK.E "sp|P46777|RL5_HUMAN,tr|A0A2R8Y6J3|A0A2R8Y6J3_HUMAN" 2 1184.5462 0.52 78925 8815 2 1184.545111 593.2804 60S ribosomal protein L5 OS=Homo sapiens OX=9606 GN=RPL5 PE=1 SV=3 6.07 1887.4 - 910652 - - - -0.921 - 2.148 0.397 - 659.1 1 2 0 -0.0011 10 0 0 0 3.54E+07 6.82E+07 - - - 4.107 1 221125_WJC_METTL3_EV_vs_WT_F06.08816.08816.2 0.00149 24-Nov R.TAPGMGDQSGC[160.03]YR.C "sp|Q9BWF3|RBM4_HUMAN,sp|Q9BQ04|RBM4B_HUMAN,tr|E9PB51|E9PB51_HUMAN" 3 1398.5656 1.34 78926 8816 2 1399.567174 700.2901 RNA-binding protein 4 OS=Homo sapiens OX=9606 GN=RBM4 PE=1 SV=1 5.5 1887.6 - 561017 - - - 716.1194 - 1.899 0.73 - 389.3 1 2 0 1.0015 13 0 0 0 4.89E+08 3.66E+08 - - - 5.7643 0.9921 221125_WJC_METTL3_EV_vs_WT_F06.08817.08817.2 1.98E-05 22-Oct H.ATQGPAATPYHC[160.03].- sp|Q9BYD3|RM04_HUMAN 1 1272.5557 - 78927 8817 2 1272.554666 637.2851 "39S ribosomal protein L4, mitochondrial OS=Homo sapiens OX=9606 GN=MRPL4 PE=1 SV=1" 6.77 1887.7 - 511820 - - - -0.829 - 2.096 0.528 - 375.8 1 1 0 -0.0011 12 0 0 0 - - - - - 4.8876 0.9999 221125_WJC_METTL3_EV_vs_WT_F06.08821.08821.2 0.00493 13/20 R.HSLASSEYPVR.R sp|P51570|GALK1_HUMAN 1 1244.6149 1.99 78929 8821 2 1244.615961 623.3148 Galactokinase OS=Homo sapiens OX=9606 GN=GALK1 PE=1 SV=1 6.75 1888.2 - 4.82E+06 - - - 0.8123 - 2.717 0.44 - 453.5 1 2 0 0.001 11 0 0 0 1.19E+08 6.00E+07 - - - 4.9945 0.9999 221125_WJC_METTL3_EV_vs_WT_F06.08823.08823.3 0.000361 13/44 K.QR[166.11]YPDGIISK[136.11]PK[136.11].N sp|Q86U44|MTA70_HUMAN 1 1426.8143 0 78931 8823 3 1426.814156 476.612 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 9.7 1888.3 - 3.24E+06 - - - -0.0792 - 2.277 0.502 - 274.7 1 2 1 -0.0001 12 0 0 0 1.15E+05 6.49E+07 - - - 6.4176 0.9999 221125_WJC_METTL3_EV_vs_WT_F06.08825.08825.2 5.77E-08 24-Dec R.TAPGMGDQSGC[160.03]YR[166.11].C "sp|Q9BWF3|RBM4_HUMAN,sp|Q9BQ04|RBM4B_HUMAN,tr|E9PB51|E9PB51_HUMAN" 3 1408.5739 1.34 78933 8825 2 1408.57286 705.2942 RNA-binding protein 4 OS=Homo sapiens OX=9606 GN=RBM4 PE=1 SV=1 5.5 1888.5 - 1.65E+06 - - - -0.7412 - 1.985 0.649 - 374.2 1 2 0 -0.001 13 0 0 0 4.89E+08 3.66E+08 - - - 5.5938 0.9999 221125_WJC_METTL3_EV_vs_WT_F06.08826.08826.2 2.11E-06 14/28 K.TATGPSTGGGTVISR[166.11].T "sp|Q8N1G0|ZN687_HUMAN,tr|H0Y5I5|H0Y5I5_HUMAN,tr|F8WCX2|F8WCX2_HUMAN" 3 1370.7029 0.82 78934 8826 2 1370.70266 686.3587 Zinc finger protein 687 OS=Homo sapiens OX=9606 GN=ZNF687 PE=1 SV=1 9.41 1888.6 - 567351 - - - -0.1948 - 2.828 0.535 - 627.9 1 2 0 -0.0003 15 0 0 0 2.24E+07 2.73E+07 - - - 5.5483 0.9992 221125_WJC_METTL3_EV_vs_WT_F06.08828.08828.2 0.0509 20-Aug K.SYYKPDSPEYK.A "sp|Q86U86|PB1_HUMAN,tr|H0Y5B5|H0Y5B5_HUMAN,tr|E7EVG2|E7EVG2_HUMAN,tr|C9JPI5|C9JPI5_HUMAN,tr|C9JQF1|C9JQF1_HUMAN" 5 1375.6296 2.58 78936 8828 2 1375.630953 688.8221 Protein polybromo-1 OS=Homo sapiens OX=9606 GN=PBRM1 PE=1 SV=1 5.79 1888.9 - 396076 - - - 0.9857 - 1.643 0.332 - 144.9 1 2 0 0.0014 11 0 0 0 5.78E+06 2.24E+06 - - - 2.8359 0.918 221125_WJC_METTL3_EV_vs_WT_F06.08830.08830.2 0.000157 20-Oct K.QVDLESNPQNR.S "sp|P42694|HELZ_HUMAN,tr|J3QS41|J3QS41_HUMAN" 2 1298.6215 3.14 78937 8830 2 1299.627562 650.318 Probable helicase with zinc finger domain OS=Homo sapiens OX=9606 GN=HELZ PE=1 SV=2 4.37 1889.1 - 472514 - - - 774.7215 - 1.766 0.3 - 296.8 1 2 0 1.0061 11 0 0 0 4.45E+07 1.42E+07 - - - 2.4794 0.9999 221125_WJC_METTL3_EV_vs_WT_F06.08832.08832.3 0.00273 Sep-40 K.SYYKPDSPEYK.A "sp|Q86U86|PB1_HUMAN,tr|H0Y5B5|H0Y5B5_HUMAN,tr|E7EVG2|E7EVG2_HUMAN,tr|C9JPI5|C9JPI5_HUMAN,tr|C9JQF1|C9JQF1_HUMAN" 5 1375.6296 1.53 78938 8832 3 1375.62915 459.5505 Protein polybromo-1 OS=Homo sapiens OX=9606 GN=PBRM1 PE=1 SV=1 5.79 1889.3 - 4.49E+06 - - - -0.3249 - 1.772 0.465 - 82.1 1 2 0 -0.0004 11 0 0 0 6.20E+07 4.04E+07 - - - 5.3494 0.9999 221125_WJC_METTL3_EV_vs_WT_F06.08833.08833.3 3.77E-05 14/44 R.LNQSPSLAPVKR.T "sp|Q9H2P0|ADNP_HUMAN,tr|A0A2R8Y6X0|A0A2R8Y6X0_HUMAN,tr|A0A669KBJ7|A0A669KBJ7_HUMAN" 3 1308.7514 1.57 78939 8833 3 1308.750251 437.2577 Activity-dependent neuroprotector homeobox protein OS=Homo sapiens OX=9606 GN=ADNP PE=1 SV=1 11 1889.4 - 4.24E+06 - - - -0.8657 - 2.279 0.419 - 378.5 1 2 0 -0.0011 12 0 0 0 8.27E+07 5.26E+07 - - - 5.4944 1 221125_WJC_METTL3_EV_vs_WT_F06.08836.08836.2 7.54E-10 15/28 K.TATGPSTGGGTVISR.T "sp|Q8N1G0|ZN687_HUMAN,tr|H0Y5I5|H0Y5I5_HUMAN,tr|F8WCX2|F8WCX2_HUMAN" 3 1360.6947 0.82 78942 8836 2 1360.695867 681.3546 Zinc finger protein 687 OS=Homo sapiens OX=9606 GN=ZNF687 PE=1 SV=1 9.41 1889.7 - 726736 - - - 0.8893 - 2.953 0.616 - 844.1 1 2 0 0.0012 15 0 0 0 2.24E+07 2.73E+07 - - - 6.2526 0.9999 221125_WJC_METTL3_EV_vs_WT_F06.08841.08841.3 4.19E-05 Dec-40 K.DR[166.11]EVAEGGLPR[166.11].A "sp|Q9BUA3|SPNDC_HUMAN,tr|H0YGK9|H0YGK9_HUMAN,tr|H0YGY5|H0YGY5_HUMAN" 3 1217.6267 2.72 78945 8841 3 1217.627475 406.8829 Spindlin interactor and repressor of chromatin-binding protein OS=Homo sapiens OX=9606 GN=SPINDOC PE=1 SV=3 4.68 1890.2 - 2.29E+06 - - - 0.6045 - 2.695 0.466 - 315.3 1 2 1 0.0007 11 0 0 0 1.15E+08 4.24E+07 - - - 6.5516 0.9999 221125_WJC_METTL3_EV_vs_WT_F06.08842.08842.3 1.93E-06 16/52 K.ASGGSLQGHDAVLR.L "sp|Q8NEJ9|NGDN_HUMAN,tr|H0YJ17|H0YJ17_HUMAN,tr|G3V4G1|G3V4G1_HUMAN" 3 1366.6953 2 78946 8842 3 1366.699754 456.5724 Neuroguidin OS=Homo sapiens OX=9606 GN=NGDN PE=1 SV=1 6.79 1890.3 - 956097 - - - 3.2399 - 3.318 0.524 - 408.5 1 2 0 0.0044 14 0 0 0 1.56E+07 7.77E+06 - - - 7.5682 1 221125_WJC_METTL3_EV_vs_WT_F06.08844.08844.2 4.76E-07 13/24 K.SEDDESGAGELTR.E sp|P33993|MCM7_HUMAN 1 1364.5692 1.41 78948 8844 2 1364.570577 683.2919 DNA replication licensing factor MCM7 OS=Homo sapiens OX=9606 GN=MCM7 PE=1 SV=4 3.83 1890.5 - 466166 - - - 1.0223 - 2.807 0.59 - 720.4 1 2 0 0.0014 13 0 0 0 8.81E+06 6.27E+06 - - - 6.0473 0.9999 221125_WJC_METTL3_EV_vs_WT_F06.08848.08848.3 4.54E-05 13/40 R.HSLASSEYPVR.R sp|P51570|GALK1_HUMAN 1 1244.6149 0.76 78951 8848 3 1244.615735 415.8789 Galactokinase OS=Homo sapiens OX=9606 GN=GALK1 PE=1 SV=1 6.75 1891 - 1.13E+07 - - - 0.6307 - 2.57 0.355 - 227.4 1 2 0 0.0008 11 0 0 0 2.13E+08 2.80E+08 - - - 5.1792 0.9999 221125_WJC_METTL3_EV_vs_WT_F06.08850.08850.3 8.38E-05 Sep-40 R.KVVAEVYDQER.F "sp|Q9UHX1|PUF60_HUMAN,tr|A0A0J9YYL3|A0A0J9YYL3_HUMAN,tr|A0A0J9YXX5|A0A0J9YXX5_HUMAN,tr|A0A0J9YXJ8|A0A0J9YXJ8_HUMAN,tr|A0A0J9YVP6|A0A0J9YVP6_HUMAN" 5 1334.683 13.87 78952 8850 3 1334.682991 445.9016 Poly(U)-binding-splicing factor PUF60 OS=Homo sapiens OX=9606 GN=PUF60 PE=1 SV=1 4.68 1891.2 - 6.51E+06 - - - -0.0292 - 2.011 0.428 - 108.7 1 2 0 0 11 0 0 0 9.50E+08 6.85E+07 - - - 5.2965 0.9998 221125_WJC_METTL3_EV_vs_WT_F06.08851.08851.2 0.00668 20-Dec R.HSLASSEYPVR[166.11].R sp|P51570|GALK1_HUMAN 1 1254.6232 2 78953 8851 2 1254.625589 628.3189 Galactokinase OS=Homo sapiens OX=9606 GN=GALK1 PE=1 SV=1 6.75 1891.3 - 2.64E+06 - - - 1.8882 - 2.461 0.555 - 377.5 1 2 0 0.0024 11 0 0 0 1.20E+08 6.01E+07 - - - 5.5757 0.9998 221125_WJC_METTL3_EV_vs_WT_F06.08853.08853.2 1.60E-05 20-Aug R.TGNGPMSVC[160.03]GR.C "sp|O95793|STAU1_HUMAN,tr|Q5JW30|Q5JW30_HUMAN" 2 1134.491 0.37 78955 8853 2 1134.49029 568.2528 Double-stranded RNA-binding protein Staufen homolog 1 OS=Homo sapiens OX=9606 GN=STAU1 PE=1 SV=2 7.91 1891.5 - 431970 - - - -0.6364 - 1.545 0.565 - 162.8 1 2 0 -0.0007 11 0 0 0 5.17E+06 1.38E+07 - - - 4.3907 0.9987 221125_WJC_METTL3_EV_vs_WT_F06.08859.08859.2 0.00255 20-Nov K.VTNIGNQQIDK.V "sp|Q6P3W7|SCYL2_HUMAN,tr|F8VSC5|F8VSC5_HUMAN,tr|A0A0U1RQQ9|A0A0U1RQQ9_HUMAN" 3 1228.6412 1.88 78959 8859 2 1228.643091 615.3279 SCY1-like protein 2 OS=Homo sapiens OX=9606 GN=SCYL2 PE=1 SV=1 5.81 1892.2 - 2.15E+06 - - - 1.5676 - 2.05 0.228 - 387.6 1 2 0 0.0019 11 0 0 0 2.73E+08 1.45E+08 - - - 2.6663 0.9939 221125_WJC_METTL3_EV_vs_WT_F06.08860.08860.2 0.00195 20-Oct K.VTNIGNQQIDK[136.11].V "sp|Q6P3W7|SCYL2_HUMAN,tr|F8VSC5|F8VSC5_HUMAN,tr|A0A0U1RQQ9|A0A0U1RQQ9_HUMAN" 3 1236.6554 1.88 78960 8860 2 1236.65665 619.335 SCY1-like protein 2 OS=Homo sapiens OX=9606 GN=SCYL2 PE=1 SV=1 5.81 1892.3 - 1.40E+06 - - - 1.0391 - 1.423 0.16 - 189.7 1 2 0 0.0013 11 0 0 0 2.73E+08 1.45E+08 - - - 1.1767 0.9985 221125_WJC_METTL3_EV_vs_WT_F06.08861.08861.2 1.81E-05 20-Oct K.QQNEGDSIISK.L "sp|Q15643|TRIPB_HUMAN,tr|H0YJ97|H0YJ97_HUMAN" 2 1217.5888 1.23 78961 8861 2 1217.583979 609.8017 Thyroid receptor-interacting protein 11 OS=Homo sapiens OX=9606 GN=TRIP11 PE=1 SV=3 4.37 1892.4 - 942938 - - - -3.9554 - 1.891 0.485 - 331.4 1 2 0 -0.0048 11 0 0 0 8.84E+07 7.19E+07 - - - 4.3452 0.8544 221125_WJC_METTL3_EV_vs_WT_F06.08862.08862.3 1.02 Jul-36 K.RFPGYDSESK.E "sp|P46777|RL5_HUMAN,tr|A0A2R8Y6J3|A0A2R8Y6J3_HUMAN" 2 1184.5462 0.61 78962 8862 3 1184.548141 395.856 60S ribosomal protein L5 OS=Homo sapiens OX=9606 GN=RPL5 PE=1 SV=3 6.07 1892.5 - 829116 - - - 1.6369 - 1.145 0.156 - 47.6 3 2 0 0.0019 10 0 0 0 1.73E+07 2.84E+07 - - - 0.4533 0.9999 221125_WJC_METTL3_EV_vs_WT_F06.08863.08863.2 1.84E-07 14/22 R.TDENIDTPGTPK.T "sp|Q6ULP2|AFTIN_HUMAN,tr|A0A0U1RR74|A0A0U1RR74_HUMAN,tr|B8ZZI9|B8ZZI9_HUMAN" 3 1286.599 1.32 78963 8863 2 1286.600346 644.3068 Aftiphilin OS=Homo sapiens OX=9606 GN=AFTPH PE=1 SV=3 4.03 1892.6 - 778336 - - - 1.0267 - 2.715 0.508 - 935.3 1 2 0 0.0013 12 0 0 0 5.26E+07 4.00E+07 - - - 5.4207 0.9998 221125_WJC_METTL3_EV_vs_WT_F06.08864.08864.2 0.00277 20-Oct K.QVDLESNPQNR[166.11].S "sp|P42694|HELZ_HUMAN,tr|J3QS41|J3QS41_HUMAN" 2 1308.6298 3.11 78964 8864 2 1308.629914 655.3222 Probable helicase with zinc finger domain OS=Homo sapiens OX=9606 GN=HELZ PE=1 SV=2 4.37 1892.7 - 566229 - - - 0.1162 - 1.952 0.469 - 509.8 1 2 0 0.0002 11 0 0 0 4.42E+07 1.42E+07 - - - 4.3144 1 221125_WJC_METTL3_EV_vs_WT_F06.08865.08865.2 5.97E-09 13/24 K.SEDDESGAGELTR[166.11].E sp|P33993|MCM7_HUMAN 1 1374.5775 1.5 78965 8865 2 1374.570422 688.296 DNA replication licensing factor MCM7 OS=Homo sapiens OX=9606 GN=MCM7 PE=1 SV=4 3.83 1892.9 - 422340 - - - -5.1143 - 2.948 0.546 - 742.4 1 2 0 -0.007 13 0 0 0 9.38E+06 6.27E+06 - - - 5.8463 0.975 221125_WJC_METTL3_EV_vs_WT_F06.08866.08866.2 0.775 14-Jul K.NDYDQLQK.A sp|P15924|DESP_HUMAN 1 1022.4669 0.54 78966 8866 2 1022.465711 512.2407 Desmoplakin OS=Homo sapiens OX=9606 GN=DSP PE=1 SV=3 4.21 1893 - 291950 - - - -1.1521 - 1.066 0.127 - 130.2 1 2 0 -0.0012 8 0 0 0 4.85E+06 9.04E+06 - - - 0.1714 0.9998 221125_WJC_METTL3_EV_vs_WT_F06.08871.08871.2 0.00194 18-Sep R.GPLPLSSQHR[166.11].G "sp|P43243|MATR3_HUMAN,tr|A8MXP9|A8MXP9_HUMAN,tr|D6R991|D6R991_HUMAN,tr|A0A0R4J2E8|A0A0R4J2E8_HUMAN,tr|D6R8Z5|D6R8Z5_HUMAN,tr|D6REM6|D6REM6_HUMAN" 6 1100.5966 1.81 78969 8871 2 1100.597136 551.3056 Matrin-3 OS=Homo sapiens OX=9606 GN=MATR3 PE=1 SV=2 9.76 1893.6 - 7.25E+06 - - - 0.4761 - 1.832 0.477 - 303.5 1 2 0 0.0005 10 0 0 0 1.81E+08 1.00E+08 - - - 4.2538 0.9402 221125_WJC_METTL3_EV_vs_WT_F06.08872.08872.3 0.0661 Sep-36 K.TFQTLEC[160.03]QHK[136.11].R sp|Q5UIP0|RIF1_HUMAN 1 1298.6169 0.83 78970 8872 3 1298.616382 433.8796 Telomere-associated protein RIF1 OS=Homo sapiens OX=9606 GN=RIF1 PE=1 SV=2 6.41 1893.7 - 1.49E+06 - - - -0.3766 - 1.518 0.089 - 104.7 1 2 0 -0.0005 10 0 0 0 1.48E+07 1.79E+07 - - - 0.7511 0.9973 221125_WJC_METTL3_EV_vs_WT_F06.08877.08877.2 3.74E-08 22-Dec K.TIQVDNTDAEGR.L sp|P28838|AMPL_HUMAN 1 1317.6161 1.07 78975 8877 2 1317.622618 659.8153 Cytosol aminopeptidase OS=Homo sapiens OX=9606 GN=LAP3 PE=1 SV=3 4.03 1894.2 - 585707 - - - 4.9673 - 2.377 0.45 - 407.6 1 2 0 0.0065 12 0 0 0 5.01E+06 4.67E+06 - - - 4.6408 0.9999 221125_WJC_METTL3_EV_vs_WT_F06.08886.08886.2 0.000478 18-Dec K.YEELQQTAGR.H "sp|P13647|K2C5_HUMAN,tr|H0YI76|H0YI76_HUMAN,tr|H0YIN9|H0YIN9_HUMAN" 3 1193.5677 2.25 78982 8886 2 1193.568481 597.7911 "Keratin, type II cytoskeletal 5 OS=Homo sapiens OX=9606 GN=KRT5 PE=1 SV=3" 4.53 1895.4 - 3.72E+06 - - - 0.6828 - 2.295 0.581 - 606.5 1 2 0 0.0008 10 0 0 0 5.17E+07 2.30E+07 - - - 5.6508 0.9948 221125_WJC_METTL3_EV_vs_WT_F06.08892.08892.2 0.000687 18-Sep K.AGFAGDDAPR[166.11].A "sp|Q6S8J3|POTEE_HUMAN,sp|P63261|ACTG_HUMAN,sp|P68133|ACTS_HUMAN,sp|P62736|ACTA_HUMAN,sp|P68032|ACTC_HUMAN,sp|P60709|ACTB_HUMAN,sp|P63267|ACTH_HUMAN,sp|A5A3E0|POTEF_HUMAN,sp|P0CG38|POTEI_HUMAN,sp|P0CG39|POTEJ_HUMAN,tr|A0A804GS07|A0A804GS07_HUMAN,tr|I3L3I0|I3L3I0_HUMAN,tr|G5E9R0|G5E9R0_HUMAN,tr|E7EVS6|E7EVS6_HUMAN,tr|A0A6Q8PGD7|A0A6Q8PGD7_HUMAN,tr|B8ZZJ2|B8ZZJ2_HUMAN,tr|J3KT65|J3KT65_HUMAN,tr|I3L3R2|I3L3R2_HUMAN,tr|K7EM38|K7EM38_HUMAN,tr|F6QUT6|F6QUT6_HUMAN,tr|C9JTX5|C9JTX5_HUMAN,tr|A0A6Q8PH58|A0A6Q8PH58_HUMAN,tr|F6UVQ4|F6UVQ4_HUMAN,tr|F8WB63|F8WB63_HUMAN,tr|I3L1U9|I3L1U9_HUMAN,tr|A0A2R8Y793|A0A2R8Y793_HUMAN,tr|I3L4N8|I3L4N8_HUMAN,tr|C9JUM1|C9JUM1_HUMAN,tr|F8WCH0|F8WCH0_HUMAN,tr|C9JZR7|C9JZR7_HUMAN,tr|C9JFL5|C9JFL5_HUMAN,tr|A0A2R8YGF8|A0A2R8YGF8_HUMAN,tr|A6NL76|A6NL76_HUMAN,tr|A0A7P0TBL1|A0A7P0TBL1_HUMAN" 34 985.4493 2.08 78987 8892 2 985.453163 493.7319 POTE ankyrin domain family member E OS=Homo sapiens OX=9606 GN=POTEE PE=2 SV=3 4.21 1896.1 - 474195 - - - 3.9413 - 1.44 0.385 - 231.6 1 2 0 0.0039 10 0 0 0 7.11E+06 3.42E+06 - - - 2.9012 0.9998 221125_WJC_METTL3_EV_vs_WT_F06.08897.08897.2 5.53E-05 16-Oct K.SFQQSSLSR.D "sp|P43243|MATR3_HUMAN,tr|A0A1B0GX04|A0A1B0GX04_HUMAN,tr|D6RBS2|D6RBS2_HUMAN,tr|A8MXP9|A8MXP9_HUMAN,tr|D6R991|D6R991_HUMAN,tr|D6REK4|D6REK4_HUMAN,tr|D6R9F3|D6R9F3_HUMAN,tr|A0A0R4J2E8|A0A0R4J2E8_HUMAN,tr|D6RB45|D6RB45_HUMAN,tr|D6RCM3|D6RCM3_HUMAN,tr|D6R8Z5|D6R8Z5_HUMAN,tr|D6REM6|D6REM6_HUMAN" 12 1038.5094 1.18 78991 8897 2 1038.508928 520.262 Matrin-3 OS=Homo sapiens OX=9606 GN=MATR3 PE=1 SV=2 9.47 1896.7 - 1.62E+06 - - - -0.4766 - 1.91 0.48 - 391.3 1 2 0 -0.0005 9 0 0 0 1.67E+08 1.41E+08 - - - 4.4582 0.9999 221125_WJC_METTL3_EV_vs_WT_F06.08899.08899.3 0.000108 17/44 K.VTARPSQPPLPR.R "sp|Q9ULV3|CIZ1_HUMAN,tr|Q5SYW2|Q5SYW2_HUMAN,tr|F5H2X7|F5H2X7_HUMAN,tr|H0Y5D5|H0Y5D5_HUMAN,tr|Q9BTG3|Q9BTG3_HUMAN" 5 1317.7517 2.74 78992 8899 3 1317.75232 440.2578 Cip1-interacting zinc finger protein OS=Homo sapiens OX=9606 GN=CIZ1 PE=1 SV=2 12 1896.9 - 6.79E+06 - - - 0.4561 - 3.018 0.317 - 598.6 1 2 0 0.0006 12 0 0 0 4.75E+08 1.73E+08 - - - 5.1358 0.9999 221125_WJC_METTL3_EV_vs_WT_F06.08900.08900.3 1.13E-07 14/44 K.VTAR[166.11]PSQPPLPR[166.11].R "sp|Q9ULV3|CIZ1_HUMAN,tr|Q5SYW2|Q5SYW2_HUMAN,tr|F5H2X7|F5H2X7_HUMAN,tr|H0Y5D5|H0Y5D5_HUMAN,tr|Q9BTG3|Q9BTG3_HUMAN" 5 1337.7683 2.75 78993 8900 3 1337.768951 446.93 Cip1-interacting zinc finger protein OS=Homo sapiens OX=9606 GN=CIZ1 PE=1 SV=2 12 1896.9 - 3.21E+06 - - - 0.5173 - 2.813 0.357 - 352.5 1 2 0 0.0007 12 0 0 0 4.69E+08 1.71E+08 - - - 5.3868 0.9999 221125_WJC_METTL3_EV_vs_WT_F06.08901.08901.2 4.64E-06 24-Nov K.GPGEVAGTVTGQK[136.11].R "sp|Q86U44|MTA70_HUMAN,tr|F5H6D8|F5H6D8_HUMAN,tr|H0YFV6|H0YFV6_HUMAN,tr|B4DTN4|B4DTN4_HUMAN" 4 1207.6288 0.03 78994 8901 2 1207.628261 604.8217 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 6 1897 - 1.82E+06 - - - -0.4596 - 2.476 0.515 - 213.9 1 2 0 -0.0006 13 0 0 0 6.22E+08 2.37E+10 - - - 5.1715 0.9885 221125_WJC_METTL3_EV_vs_WT_F06.08903.08903.2 0.00873 16-Oct K.HNDMADLER[166.11].L sp|O15269|SPTC1_HUMAN 1 1109.4799 0.48 78996 8903 2 1110.483716 555.7472 Serine palmitoyltransferase 1 OS=Homo sapiens OX=9606 GN=SPTLC1 PE=1 SV=1 4.54 1897.2 - 806625 - - - 904.7383 - 1.722 0.462 - 245.7 1 2 0 1.0038 9 0 0 0 5.28E+06 1.11E+07 - - - 3.7105 0.9995 221125_WJC_METTL3_EV_vs_WT_F06.08904.08904.2 4.70E-06 15/24 K.TTVQQEPLESGAK.N "sp|P49750|YLPM1_HUMAN,tr|F8VU51|F8VU51_HUMAN" 2 1386.6991 2.45 78997 8904 2 1386.703233 694.3568 YLP motif-containing protein 1 OS=Homo sapiens OX=9606 GN=YLPM1 PE=1 SV=4 4.53 1897.3 - 630640 - - - 2.9992 - 2.397 0.512 - 816.9 1 2 0 0.0042 13 0 0 0 9.03E+07 3.68E+07 - - - 5.065 0.9981 221125_WJC_METTL3_EV_vs_WT_F06.08907.08907.2 0.00316 16-Sep K.K[136.11]SSETLTFK[136.11].R "sp|Q9NPF5|DMAP1_HUMAN,tr|Q5TG39|Q5TG39_HUMAN,tr|Q5TG38|Q5TG38_HUMAN,tr|Q5TG40|Q5TG40_HUMAN,tr|Q5TG36|Q5TG36_HUMAN,tr|Q5TG37|Q5TG37_HUMAN" 6 1055.5834 0.73 79000 8907 2 1055.586133 528.799 DNA methyltransferase 1-associated protein 1 OS=Homo sapiens OX=9606 GN=DMAP1 PE=1 SV=1 8.59 1897.7 - 475445 - - - 2.6118 - 1.832 0.292 - 223.6 1 2 0 0.0028 9 0 0 0 1.58E+07 2.16E+07 - - - 2.9483 0.9992 221125_WJC_METTL3_EV_vs_WT_F06.08909.08909.2 0.00131 22-Nov K.TIQVDNTDAEGR[166.11].L sp|P28838|AMPL_HUMAN 1 1327.6243 1.07 79002 8909 2 1327.620422 664.8194 Cytosol aminopeptidase OS=Homo sapiens OX=9606 GN=LAP3 PE=1 SV=3 4.03 1898 - 349947 - - - -2.9534 - 1.907 0.479 - 255.3 1 2 0 -0.0039 12 0 0 0 5.01E+06 4.67E+06 - - - 4.2762 0.9988 221125_WJC_METTL3_EV_vs_WT_F06.08913.08913.3 0.00053 Oct-40 R.VR[166.11]EEEIEVDSR[166.11].V "sp|Q14978|NOLC1_HUMAN,tr|A0A0A0MRM9|A0A0A0MRM9_HUMAN" 2 1379.6796 1.93 79004 8913 3 1379.678645 460.9005 Nucleolar and coiled-body phosphoprotein 1 OS=Homo sapiens OX=9606 GN=NOLC1 PE=1 SV=2 4.25 1898.5 - 961539 - - - -0.6654 - 2.141 0.329 - 195.5 1 2 1 -0.0009 11 0 0 0 2.03E+07 1.06E+07 - - - 4.3704 0.9961 221125_WJC_METTL3_EV_vs_WT_F06.08914.08914.3 0.0537 Nov-40 R.VREEEIEVDSR.V "sp|Q14978|NOLC1_HUMAN,tr|A0A0A0MRM9|A0A0A0MRM9_HUMAN" 2 1359.663 1.72 79005 8914 3 1359.665139 454.2283 Nucleolar and coiled-body phosphoprotein 1 OS=Homo sapiens OX=9606 GN=NOLC1 PE=1 SV=2 4.25 1898.6 - 1.42E+06 - - - 1.5563 - 2.146 0.269 - 248.5 1 2 1 0.0021 11 0 0 0 2.14E+07 1.25E+07 - - - 3.7078 0.9997 221125_WJC_METTL3_EV_vs_WT_F06.08920.08920.2 2.83E-05 13/24 K.GQIAGGINTGSAK.L "sp|Q9Y2H6|FND3A_HUMAN,tr|A0A087X1M6|A0A087X1M6_HUMAN,tr|G5E9X3|G5E9X3_HUMAN" 3 1172.6149 0.92 79011 8920 2 1172.61795 587.3148 Fibronectin type-III domain-containing protein 3A OS=Homo sapiens OX=9606 GN=FNDC3A PE=1 SV=4 8.75 1899.3 - 400028 - - - 2.5584 - 2.601 0.559 - 460.6 1 2 0 0.003 13 0 0 0 1.07E+07 1.15E+07 - - - 5.6222 0.9994 221125_WJC_METTL3_EV_vs_WT_F06.08921.08921.2 0.0249 22-Sep K.VTARPSQPPLPR.R "sp|Q9ULV3|CIZ1_HUMAN,tr|Q5SYW2|Q5SYW2_HUMAN,tr|F5H2X7|F5H2X7_HUMAN,tr|H0Y5D5|H0Y5D5_HUMAN,tr|Q9BTG3|Q9BTG3_HUMAN" 5 1317.7517 3.74 79012 8921 2 1317.750692 659.8831 Cip1-interacting zinc finger protein OS=Homo sapiens OX=9606 GN=CIZ1 PE=1 SV=2 12 1899.5 - 398666 - - - -0.7794 - 1.825 0.319 - 84.2 1 2 0 -0.001 12 0 0 0 1.95E+07 5.21E+06 - - - 2.9797 0.9987 221125_WJC_METTL3_EV_vs_WT_F06.08927.08927.3 0.0549 Aug-32 K.EIEANEWKK.K "sp|O75410|TACC1_HUMAN,tr|E7EVI4|E7EVI4_HUMAN,tr|B4E3H6|B4E3H6_HUMAN,tr|R4GMT7|R4GMT7_HUMAN,tr|H0YAY0|H0YAY0_HUMAN,tr|H0YBT8|H0YBT8_HUMAN,tr|E7ET87|E7ET87_HUMAN" 7 1145.5717 0.61 79016 8927 3 1145.572066 382.8645 Transforming acidic coiled-coil-containing protein 1 OS=Homo sapiens OX=9606 GN=TACC1 PE=1 SV=2 4.79 1900.2 - 4.54E+06 - - - 0.33 - 1.536 0.293 - 74.1 1 2 0 0.0004 9 0 0 0 4.44E+07 7.34E+07 - - - 3.1 0.9998 221125_WJC_METTL3_EV_vs_WT_F06.08928.08928.2 4.02E-06 20-Dec K.SGGNEVSIEER.L sp|Q15061|WDR43_HUMAN 1 1175.5418 0.92 79017 8928 2 1175.543423 588.7782 WD repeat-containing protein 43 OS=Homo sapiens OX=9606 GN=WDR43 PE=1 SV=3 4.25 1900.3 - 843333 - - - 1.3424 - 2.396 0.453 - 510.4 1 2 0 0.0016 11 0 0 0 9.46E+07 1.03E+08 - - - 4.7502 0.9988 221125_WJC_METTL3_EV_vs_WT_F06.08937.08937.3 0.000518 Sep-44 R.ELYDK[136.11]GGEQAIK[136.11].E sp|P31689|DNJA1_HUMAN 1 1365.7111 0.52 79024 8937 3 1365.714104 456.2443 DnaJ homolog subfamily A member 1 OS=Homo sapiens OX=9606 GN=DNAJA1 PE=1 SV=2 4.68 1901.2 - 1.57E+06 - - - 2.2025 - 2.052 0.401 - 80.8 1 2 1 0.003 12 0 0 0 1.42E+08 2.72E+08 - - - 5.0024 0.9998 221125_WJC_METTL3_EV_vs_WT_F06.08944.08944.2 8.95E-05 20-Nov K.QLQQEC[160.03]EQLQK.M "sp|Q9Y2K2|SIK3_HUMAN,tr|H0Y4E8|H0Y4E8_HUMAN" 2 1430.6824 1.55 79031 8944 2 1430.682041 716.3485 Serine\threonine-protein kinase SIK3 OS=Homo sapiens OX=9606 GN=SIK3 PE=1 SV=4 4.53 1902 - 279833 - - - -0.2356 - 1.968 0.472 - 418.5 1 2 0 -0.0003 11 0 0 0 3.64E+06 2.35E+06 - - - 4.3586 0.9998 221125_WJC_METTL3_EV_vs_WT_F06.08947.08947.2 9.73E-06 24-Nov K.VMEQQSNLQPEAK.E "sp|Q8IWI9|MGAP_HUMAN,tr|H3BU53|H3BU53_HUMAN" 2 1500.7242 1.87 79034 8947 2 1500.722903 751.3694 MAX gene-associated protein OS=Homo sapiens OX=9606 GN=MGA PE=1 SV=4 4.53 1902.4 - 198678 - - - -0.8929 - 1.945 0.514 - 265.3 1 2 0 -0.0013 13 0 0 0 6.59E+06 3.53E+06 - - - 4.5444 0.9998 221125_WJC_METTL3_EV_vs_WT_F06.08951.08951.3 2.81E-05 13/40 K.VSNRFSGVPDR.F "sp|A0A075B6R9|KVD24_HUMAN,sp|A0A075B6S2|KVD29_HUMAN,sp|A0A0A0MRZ7|KVD26_HUMAN" 3 1232.6262 265.27 79036 8951 3 1232.627047 411.8827 Probable non-functional immunoglobulin kappa variable 2D-24 OS=Homo sapiens OX=9606 GN=IGKV2D-24 PE=1 SV=1 9.57 1902.8 - 7.12E+06 - - - 0.7001 - 2.21 0.462 - 271 1 2 1 0.0009 11 0 0 0 1.20E+09 4.52E+06 - - - 5.9434 0.9878 221125_WJC_METTL3_EV_vs_WT_F06.08953.08953.3 0.722 Nov-32 K.EEQIEELK[136.11]R[166.11].Q "sp|Q15643|TRIPB_HUMAN,tr|H0YJI2|H0YJI2_HUMAN,tr|H0YJ97|H0YJ97_HUMAN" 3 1190.6262 1.15 79038 8953 3 1190.626651 397.8827 Thyroid receptor-interacting protein 11 OS=Homo sapiens OX=9606 GN=TRIP11 PE=1 SV=3 4.49 1902.9 - 1.48E+06 - - - 0.3897 - 1.673 0.143 - 186.3 1 2 0 0.0005 9 0 0 0 4.92E+07 4.28E+07 - - - 1.6851 0.9986 221125_WJC_METTL3_EV_vs_WT_F06.08956.08956.2 8.74E-06 22-Dec R.ELYDK[136.11]GGEQAIK[136.11].E sp|P31689|DNJA1_HUMAN 1 1365.7111 0.48 79041 8956 2 1365.710091 683.8628 DnaJ homolog subfamily A member 1 OS=Homo sapiens OX=9606 GN=DNAJA1 PE=1 SV=2 4.68 1903.3 - 593370 - - - -0.7359 - 2.504 0.471 - 460.2 1 2 1 -0.001 12 0 0 0 2.01E+07 4.18E+07 - - - 4.9346 0.9998 221125_WJC_METTL3_EV_vs_WT_F06.08959.08959.2 8.75E-06 15/24 K.TLGTPTQPGSTPR.L sp|Q8NFH5|NUP35_HUMAN 1 1311.6783 0.96 79044 8959 2 1311.676142 656.8464 Nucleoporin NUP35 OS=Homo sapiens OX=9606 GN=NUP35 PE=1 SV=1 9.41 1903.7 - 451047 - - - -1.6292 - 2.406 0.527 - 685.9 1 2 0 -0.0021 13 0 0 0 1.02E+07 1.06E+07 - - - 5.1861 0.8702 221125_WJC_METTL3_EV_vs_WT_F06.08960.08960.2 0.000953 18-Dec V.SNRFSGVPDR.F "sp|A0A075B6R9|KVD24_HUMAN,sp|A0A0C4DH68|KV224_HUMAN,sp|A0A075B6S2|KVD29_HUMAN,sp|A0A0A0MRZ7|KVD26_HUMAN" 4 1133.5578 371.66 79045 8960 2 1133.558699 567.7862 Probable non-functional immunoglobulin kappa variable 2D-24 OS=Homo sapiens OX=9606 GN=IGKV2D-24 PE=1 SV=1 9.31 1903.8 - 432649 - - - 0.8195 - 2.092 0.422 - 279.7 1 1 1 0.0009 10 0 0 0 8.96E+07 2.41E+05 - - - 4.2179 0.9998 221125_WJC_METTL3_EV_vs_WT_F06.08961.08961.2 0.00309 14/28 K.AQAAAPASVPAQAPK.R "sp|P47914|RL29_HUMAN,tr|A0A3B3ITT5|A0A3B3ITT5_HUMAN" 2 1376.7412 0.92 79046 8961 2 1376.74051 689.3779 60S ribosomal protein L29 OS=Homo sapiens OX=9606 GN=RPL29 PE=1 SV=2 8.8 1903.9 - 354577 - - - -0.5106 - 2.528 0.427 - 564.5 1 2 0 -0.0007 15 0 0 0 1.04E+07 1.13E+07 - - - 4.4747 0.9901 221125_WJC_METTL3_EV_vs_WT_F06.08964.08964.3 0.397 Dec-32 K.EEQIEELKR.Q "sp|Q15643|TRIPB_HUMAN,tr|H0YJI2|H0YJI2_HUMAN,tr|H0YJ97|H0YJ97_HUMAN" 3 1172.6037 1.15 79048 8964 3 1172.603394 391.8752 Thyroid receptor-interacting protein 11 OS=Homo sapiens OX=9606 GN=TRIP11 PE=1 SV=3 4.49 1904.3 - 2.52E+06 - - - -0.2755 - 1.948 0.113 - 248.1 1 2 0 -0.0003 9 0 0 0 4.91E+07 4.27E+07 - - - 1.8094 0.9993 221125_WJC_METTL3_EV_vs_WT_F06.08966.08966.3 0.00269 Nov-44 R.ELYDKGGEQAIK.E sp|P31689|DNJA1_HUMAN 1 1349.6827 0.53 79049 8966 3 1349.682396 450.9015 DnaJ homolog subfamily A member 1 OS=Homo sapiens OX=9606 GN=DNAJA1 PE=1 SV=2 4.68 1904.5 - 4.26E+06 - - - -0.2223 - 2.213 0.367 - 114.1 1 2 1 -0.0003 12 0 0 0 1.43E+08 2.72E+08 - - - 4.8334 0.9998 221125_WJC_METTL3_EV_vs_WT_F06.08967.08967.2 2.51E-06 24-Oct R.EAGPSVAVDSSGR.R sp|Q99959|PKP2_HUMAN 1 1230.584 1.2 79050 8967 2 1230.582311 616.2993 Plakophilin-2 OS=Homo sapiens OX=9606 GN=PKP2 PE=1 SV=2 4.37 1904.6 - 2.11E+06 - - - -1.4083 - 2.129 0.541 - 273.6 1 2 0 -0.0017 13 0 0 0 5.67E+07 4.71E+07 - - - 4.9757 1 221125_WJC_METTL3_EV_vs_WT_F06.08968.08968.2 6.74E-07 14/22 R.TSC[160.03]LPSC[160.03]TTAAR[166.11].L "tr|H0Y641|H0Y641_HUMAN,tr|H0Y4V9|H0Y4V9_HUMAN" 2 1333.5994 1.15 79051 8968 2 1333.598747 667.807 La-related protein 4B (Fragment) OS=Homo sapiens OX=9606 GN=LARP4B PE=1 SV=2 7.75 1904.7 - 1.46E+06 - - - -0.4829 - 2.329 0.623 - 455.6 1 2 0 -0.0006 12 0 0 0 3.82E+07 3.31E+07 - - - 5.8668 1 221125_WJC_METTL3_EV_vs_WT_F06.08969.08969.2 1.52E-06 13/22 K.AAFTEC[160.03]C[160.03]QAADK.A "sp|P02768|ALBU_HUMAN,tr|B7WNR0|B7WNR0_HUMAN,tr|H0YA55|H0YA55_HUMAN,tr|A0A0C4DGB6|A0A0C4DGB6_HUMAN,tr|D6RHD5|D6RHD5_HUMAN" 5 1370.5595 999 79052 8969 2 1370.560812 686.287 Albumin OS=Homo sapiens OX=9606 GN=ALB PE=1 SV=2 4.37 1904.8 - 1.39E+06 - - - 0.9675 - 2.983 0.685 - 454 1 2 0 0.0013 12 0 0 0 5.52E+07 0.00E+00 - - - 6.9757 0.9999 221125_WJC_METTL3_EV_vs_WT_F06.08970.08970.2 8.27E-06 22-Oct R.TSC[160.03]LPSC[160.03]TTAAR.L "tr|H0Y641|H0Y641_HUMAN,tr|H0Y4V9|H0Y4V9_HUMAN" 2 1323.5911 1.15 79053 8970 2 1323.591422 662.8028 La-related protein 4B (Fragment) OS=Homo sapiens OX=9606 GN=LARP4B PE=1 SV=2 7.75 1904.9 - 1.29E+06 - - - 0.2274 - 1.825 0.576 - 174.6 1 2 0 0.0003 12 0 0 0 3.82E+07 3.31E+07 - - - 4.8781 0.9999 221125_WJC_METTL3_EV_vs_WT_F06.08971.08971.3 0.0021 Nov-48 K.FGVSSESK[136.11]PEEVK[136.11].K sp|P49790|NU153_HUMAN 1 1437.7322 1.72 79054 8971 3 1437.734029 480.2514 Nuclear pore complex protein Nup153 OS=Homo sapiens OX=9606 GN=NUP153 PE=1 SV=2 4.79 1904.9 - 1.17E+06 - - - 1.2548 - 2.379 0.377 - 90.6 1 2 0 0.0018 13 0 0 0 3.73E+07 2.17E+07 - - - 5.0925 0.999 221125_WJC_METTL3_EV_vs_WT_F06.08972.08972.2 0.358 22-Sep K.EAHEPLAVADAK[136.11].L sp|Q9Y2X3|NOP58_HUMAN 1 1257.6445 0.42 79055 8972 2 1257.64428 629.8295 Nucleolar protein 58 OS=Homo sapiens OX=9606 GN=NOP58 PE=1 SV=1 4.65 1905 - 967158 - - - -0.1479 - 1.61 0.279 - 186.3 1 2 0 -0.0002 12 0 0 0 9.25E+06 2.18E+07 - - - 2.3547 0.9785 221125_WJC_METTL3_EV_vs_WT_F06.08973.08973.2 0.00395 20-Nov V.TARPSQPPLPR.R "sp|Q9ULV3|CIZ1_HUMAN,tr|Q5SYW2|Q5SYW2_HUMAN,tr|F5H2X7|F5H2X7_HUMAN,tr|H0Y5D5|H0Y5D5_HUMAN,tr|Q9BTG3|Q9BTG3_HUMAN" 5 1218.6833 5.89 79056 8973 2 1218.683429 610.3489 Cip1-interacting zinc finger protein OS=Homo sapiens OX=9606 GN=CIZ1 PE=1 SV=2 12 1905.1 - 945362 - - - 0.1017 - 1.929 0.344 - 154.5 1 1 0 0.0001 11 0 0 0 1.53E+07 2.60E+06 - - - 3.3591 0.9449 221125_WJC_METTL3_EV_vs_WT_F06.08975.08975.3 0.47 Aug-32 K.FTDELEQK[136.11]R[166.11].A sp|Q9NX07|TSAP1_HUMAN 1 1182.6 0.81 79058 8975 3 1182.601772 395.2073 tRNA selenocysteine 1-associated protein 1 OS=Homo sapiens OX=9606 GN=TRNAU1AP PE=1 SV=1 4.68 1905.3 - 698630 - - - 1.5221 - 1.499 0.112 - 61.6 1 2 0 0.0018 9 0 0 0 1.36E+07 1.68E+07 - - - 1.0082 0.998 221125_WJC_METTL3_EV_vs_WT_F06.08977.08977.2 1.83E-05 22-Dec R.ELYDKGGEQAIK.E sp|P31689|DNJA1_HUMAN 1 1349.6827 0.48 79060 8977 2 1349.680498 675.8486 DnaJ homolog subfamily A member 1 OS=Homo sapiens OX=9606 GN=DNAJA1 PE=1 SV=2 4.68 1905.5 - 567935 - - - -1.6285 - 2.424 0.507 - 428.7 1 2 1 -0.0022 12 0 0 0 2.02E+07 4.18E+07 - - - 5.1147 0.9943 221125_WJC_METTL3_EV_vs_WT_F06.08978.08978.3 0.0101 Jul-40 R.VPVK[136.11]DVVDPSK[136.11].V "sp|O75369|FLNB_HUMAN,tr|E7EN95|E7EN95_HUMAN,tr|A0A804HK76|A0A804HK76_HUMAN,tr|A0A804HL72|A0A804HL72_HUMAN" 4 1197.694 0.42 79061 8978 3 1197.694741 400.2386 Filamin-B OS=Homo sapiens OX=9606 GN=FLNB PE=1 SV=2 5.93 1905.6 - 500338 - - - 0.6279 - 1.626 0.303 - 57.8 2 2 1 0.0008 11 0 0 0 1.41E+07 3.33E+07 - - - 3.1596 0.9999 221125_WJC_METTL3_EV_vs_WT_F06.08986.08986.2 2.65E-07 13/22 K.GTDDSMTLQSQK.F "sp|O00422|SAP18_HUMAN,tr|H7BZW6|H7BZW6_HUMAN" 2 1309.582 1.29 79067 8986 2 1309.581578 655.7983 Histone deacetylase complex subunit SAP18 OS=Homo sapiens OX=9606 GN=SAP18 PE=1 SV=1 4.21 1906.5 - 753961 - - - -0.3184 - 2.551 0.484 - 893.1 1 2 0 -0.0004 12 0 0 0 2.55E+07 1.98E+07 - - - 5.0797 0.9996 221125_WJC_METTL3_EV_vs_WT_F06.08992.08992.2 0.000412 20-Aug K.EAK[136.11]PDELMDSK[136.11].L sp|Q9P0L0|VAPA_HUMAN 1 1277.6144 0.82 79071 8992 2 1277.616353 639.8145 Vesicle-associated membrane protein-associated protein A OS=Homo sapiens OX=9606 GN=VAPA PE=1 SV=3 4.32 1907.3 - 431754 - - - 1.5145 - 1.629 0.499 - 112.7 1 2 0 0.0019 11 0 0 0 4.19E+06 5.08E+06 - - - 4.0461 0.9997 221125_WJC_METTL3_EV_vs_WT_F06.08994.08994.2 0.000106 24-Jul K.VMEQQSNLQPEAK[136.11].E "sp|Q8IWI9|MGAP_HUMAN,tr|H3BU53|H3BU53_HUMAN" 2 1508.7384 1.87 79073 8994 2 1508.74112 755.3765 MAX gene-associated protein OS=Homo sapiens OX=9606 GN=MGA PE=1 SV=4 4.53 1907.5 - 224808 - - - 1.7743 - 1.674 0.559 - 115.5 1 2 0 0.0027 13 0 0 0 6.59E+06 3.53E+06 - - - 4.4913 1 221125_WJC_METTL3_EV_vs_WT_F06.08997.08997.3 0.0021 18/44 R.SQLLGSAHEVQR.F "sp|Q13813|SPTN1_HUMAN,tr|A0A0D9SF54|A0A0D9SF54_HUMAN,tr|A0A0D9SGF6|A0A0D9SGF6_HUMAN" 3 1323.6895 1.75 79074 8997 3 1323.691293 442.2371 "Spectrin alpha chain, non-erythrocytic 1 OS=Homo sapiens OX=9606 GN=SPTAN1 PE=1 SV=3" 6.47 1907.9 - 5.39E+06 - - - 1.3455 - 3.032 0.461 - 483.8 1 2 0 0.0018 12 0 0 0 1.05E+08 6.00E+07 - - - 6.7538 0.955 221125_WJC_METTL3_EV_vs_WT_F06.08998.08998.3 1.12 Oct-32 R.QR[166.11]ELEIEER[166.11].E sp|Q14152|EIF3A_HUMAN 1 1220.6264 1.15 79075 8998 3 1220.627218 407.8827 Eukaryotic translation initiation factor 3 subunit A OS=Homo sapiens OX=9606 GN=EIF3A PE=1 SV=1 4.49 1908 - 2.72E+06 - - - 0.6661 - 1.884 0.121 - 206.8 1 2 1 0.0008 9 0 0 0 5.94E+07 5.15E+07 - - - 1.7977 0.9679 221125_WJC_METTL3_EV_vs_WT_F06.08999.08999.3 0.00301 Aug-32 K.FTDELEQKR.A sp|Q9NX07|TSAP1_HUMAN 1 1164.5775 0.8 79076 8999 3 1164.585121 389.1998 tRNA selenocysteine 1-associated protein 1 OS=Homo sapiens OX=9606 GN=TRNAU1AP PE=1 SV=1 4.68 1908 - 1.17E+06 - - - 6.5423 - 1.534 0.333 - 67.8 1 2 0 0.0076 9 0 0 0 1.34E+07 1.68E+07 - - - 3.54 0.9996 221125_WJC_METTL3_EV_vs_WT_F06.09000.09000.2 0.183 16-Dec K.K[136.11]ALEDVVQR[166.11].S "sp|Q14966|ZN638_HUMAN,tr|A0A096LPB4|A0A096LPB4_HUMAN,tr|A0A096LNX0|A0A096LNX0_HUMAN,tr|A0A096LPI0|A0A096LPI0_HUMAN,tr|A0A096LNQ0|A0A096LNQ0_HUMAN,tr|A0A096LNR2|A0A096LNR2_HUMAN" 6 1074.6152 1.45 79077 9000 2 1074.616628 538.3149 Zinc finger protein 638 OS=Homo sapiens OX=9606 GN=ZNF638 PE=1 SV=2 6.07 1908.1 - 998195 - - - 1.3028 - 2.342 0.315 - 603.7 1 2 0 0.0014 9 0 0 0 1.65E+07 1.14E+07 - - - 3.8292 0.9993 221125_WJC_METTL3_EV_vs_WT_F06.09002.09002.3 0.0169 Oct-48 R.VLSGTIHAGQPVK.V sp|Q15029|U5S1_HUMAN 1 1305.7405 2.49 79079 9002 3 1305.741839 436.2541 116 kDa U5 small nuclear ribonucleoprotein component OS=Homo sapiens OX=9606 GN=EFTUD2 PE=1 SV=1 8.73 1908.3 - 823600 - - - 1.037 - 2.215 0.266 - 145.5 1 2 0 0.0014 13 0 0 0 2.79E+07 1.12E+07 - - - 3.6614 0.9999 221125_WJC_METTL3_EV_vs_WT_F06.09003.09003.3 0.00108 Nov-60 K.VLTGVAGEDAEC[160.03]HAAK.L sp|O95373|IPO7_HUMAN 1 1626.7672 1.99 79080 9003 3 1626.767561 543.263 Importin-7 OS=Homo sapiens OX=9606 GN=IPO7 PE=1 SV=1 4.65 1908.4 - 498658 - - - 0.2397 - 2.108 0.406 - 63 1 2 0 0.0004 16 0 0 0 1.66E+07 8.32E+06 - - - 4.9799 0.9994 221125_WJC_METTL3_EV_vs_WT_F06.09005.09005.2 0.00169 24-Jul K.FGVSSESKPEEVK.K sp|P49790|NU153_HUMAN 1 1421.7038 3.66 79082 9005 2 1421.703469 711.8592 Nuclear pore complex protein Nup153 OS=Homo sapiens OX=9606 GN=NUP153 PE=1 SV=2 4.79 1908.7 - 202465 - - - -0.2504 - 1.656 0.349 - 90.3 1 2 0 -0.0004 13 0 0 0 3.13E+06 8.56E+05 - - - 2.9132 0.9907 221125_WJC_METTL3_EV_vs_WT_F06.09008.09008.2 0.269 14-Aug R.DGPMK[136.11]FEK[136.11].D "sp|Q8ND56|LS14A_HUMAN,tr|A0A140TA76|A0A140TA76_HUMAN,tr|K7EMZ9|K7EMZ9_HUMAN" 3 966.4816 0.95 79083 9008 2 966.481276 484.2481 Protein LSM14 homolog A OS=Homo sapiens OX=9606 GN=LSM14A PE=1 SV=3 6.07 1909.1 - 6.22E+06 - - - -0.2866 - 1.755 0.243 - 313.3 1 2 1 -0.0003 8 0 0 0 9.80E+07 1.03E+08 - - - 2.5321 0.9984 221125_WJC_METTL3_EV_vs_WT_F06.09009.09009.2 0.00023 14-Nov R.DGPMKFEK.D "sp|Q8ND56|LS14A_HUMAN,tr|A0A140TA76|A0A140TA76_HUMAN,tr|K7EMZ9|K7EMZ9_HUMAN" 3 950.4532 0.95 79084 9009 2 950.453045 476.2339 Protein LSM14 homolog A OS=Homo sapiens OX=9606 GN=LSM14A PE=1 SV=3 6.07 1909.1 - 4.89E+06 - - - -0.1136 - 2.099 0.451 - 558.6 1 2 1 -0.0001 8 0 0 0 9.86E+07 1.04E+08 - - - 4.6083 1 221125_WJC_METTL3_EV_vs_WT_F06.09010.09010.3 0.000126 18/44 R.SQLLGSAHEVQR[166.11].F "sp|Q13813|SPTN1_HUMAN,tr|A0A0D9SF54|A0A0D9SF54_HUMAN,tr|A0A0D9SGF6|A0A0D9SGF6_HUMAN" 3 1333.6978 1.98 79085 9010 3 1333.698492 445.5732 "Spectrin alpha chain, non-erythrocytic 1 OS=Homo sapiens OX=9606 GN=SPTAN1 PE=1 SV=3" 6.47 1909.2 - 4.20E+06 - - - 0.5324 - 3.212 0.49 - 768.5 1 2 0 0.0007 12 0 0 0 1.19E+08 6.01E+07 - - - 7.2373 1 221125_WJC_METTL3_EV_vs_WT_F06.09013.09013.3 2.21E-09 17/52 R.TPYVTTTVSAHSAK[136.11].V "sp|Q9BSJ2|GCP2_HUMAN,tr|A0A804HLH6|A0A804HLH6_HUMAN,tr|A0A804HJH7|A0A804HJH7_HUMAN,tr|F2Z2B9|F2Z2B9_HUMAN,tr|R4GMM4|R4GMM4_HUMAN,tr|A0A804HK74|A0A804HK74_HUMAN,tr|A0A804HL95|A0A804HL95_HUMAN,tr|A0A804HJ08|A0A804HJ08_HUMAN,tr|A0A804HJQ4|A0A804HJQ4_HUMAN,tr|A0A804HJS9|A0A804HJS9_HUMAN,tr|A0A804HL05|A0A804HL05_HUMAN,tr|A0A804HI27|A0A804HI27_HUMAN" 12 1469.7606 1.57 79088 9013 3 1469.759509 490.9275 Gamma-tubulin complex component 2 OS=Homo sapiens OX=9606 GN=TUBGCP2 PE=1 SV=2 8.29 1909.4 - 801702 - - - -0.7137 - 3.373 0.545 - 387.5 1 2 0 -0.001 14 0 0 0 1.73E+07 1.10E+07 - - - 7.847 0.9939 221125_WJC_METTL3_EV_vs_WT_F06.09016.09016.3 0.0162 Jul-36 K.FEENQK[136.11]EFER[166.11].V "sp|Q9BZJ0|CRNL1_HUMAN,tr|Q5JY65|Q5JY65_HUMAN" 2 1372.6378 1.28 79091 9016 3 1372.634698 458.5532 Crooked neck-like protein 1 OS=Homo sapiens OX=9606 GN=CRNKL1 PE=1 SV=4 4.49 1909.7 - 560182 - - - -2.2701 - 1.36 0.38 - 43.8 1 2 1 -0.0031 10 0 0 0 2.18E+07 1.70E+07 - - - 3.6737 0.9958 221125_WJC_METTL3_EV_vs_WT_F06.09019.09019.3 0.00306 Oct-48 K.AIEKGETLPTEAR.F sp|Q8IZH2|XRN1_HUMAN 1 1413.7464 1.3 79092 9019 3 1413.746724 472.2561 5'-3' exoribonuclease 1 OS=Homo sapiens OX=9606 GN=XRN1 PE=1 SV=1 4.79 1910.1 - 1.48E+06 - - - 0.2589 - 1.836 0.285 - 162.1 1 2 1 0.0004 13 0 0 0 3.81E+07 2.93E+07 - - - 3.3647 0.9776 221125_WJC_METTL3_EV_vs_WT_F06.09020.09020.2 0.0197 16-Dec R.QR[166.11]ELEIEER[166.11].E sp|Q14152|EIF3A_HUMAN 1 1220.6264 3.31 79093 9020 2 1220.629483 611.3205 Eukaryotic translation initiation factor 3 subunit A OS=Homo sapiens OX=9606 GN=EIF3A PE=1 SV=1 4.49 1910.2 - 825499 - - - 2.5217 - 2.02 0.235 - 371 1 2 1 0.0031 9 0 0 0 3.29E+07 9.94E+06 - - - 2.8098 0.9999 221125_WJC_METTL3_EV_vs_WT_F06.09022.09022.2 0.000179 18-Nov R.SAETSWDTNK.T tr|A0A1B0GVI3|A0A1B0GVI3_HUMAN 1 1137.4938 37.25 79095 9022 2 1137.493812 569.7542 "Keratin, type I cytoskeletal 10 OS=Homo sapiens OX=9606 GN=KRT10 PE=1 SV=2" 4.37 1910.3 - 1.95E+06 - - - -0.0176 - 2.45 0.539 - 460.5 1 2 0 0 10 0 0 0 3.81E+07 1.02E+06 - - - 5.5233 0.9973 221125_WJC_METTL3_EV_vs_WT_F06.09023.09023.3 0.0534 Nov-40 R.NLNGHSIGQYR[166.11].L "sp|P50579|MAP2_HUMAN,tr|F8VQZ7|F8VQZ7_HUMAN,tr|F8VRR3|F8VRR3_HUMAN" 3 1267.6297 0.41 79096 9023 3 1267.625547 423.5505 Methionine aminopeptidase 2 OS=Homo sapiens OX=9606 GN=METAP2 PE=1 SV=1 8.75 1910.4 - 1.16E+06 - - - -3.2786 - 1.886 0.3 - 218.3 1 2 0 -0.0042 11 0 0 0 1.38E+07 3.37E+07 - - - 3.6859 0.9999 221125_WJC_METTL3_EV_vs_WT_F06.09025.09025.2 4.82E-06 28-Nov K.VASAGSAISNASGER.L sp|Q86YT6|MIB1_HUMAN 1 1375.6692 1.08 79098 9025 2 1375.669637 688.8419 E3 ubiquitin-protein ligase MIB1 OS=Homo sapiens OX=9606 GN=MIB1 PE=1 SV=1 5.97 1910.6 - 401430 - - - 0.3387 - 2.584 0.549 - 360.1 1 2 0 0.0005 15 0 0 0 5.88E+06 5.47E+06 - - - 5.4298 0.9999 221125_WJC_METTL3_EV_vs_WT_F06.09030.09030.2 1.13E-06 16-Nov K.AQYEDIAQK.S sp|P04264|K2C1_HUMAN 1 1064.5138 840.26 79101 9030 2 1064.514254 533.2642 "Keratin, type II cytoskeletal 1 OS=Homo sapiens OX=9606 GN=KRT1 PE=1 SV=6" 4.37 1911.3 - 3.81E+06 - - - 0.3898 - 1.883 0.538 - 532.4 1 2 0 0.0004 9 0 0 0 7.95E+08 9.46E+05 - - - 4.8455 0.9999 221125_WJC_METTL3_EV_vs_WT_F06.09031.09031.3 2.55E-05 14/52 R.TPYVTTTVSAHSAK.V "sp|Q9BSJ2|GCP2_HUMAN,tr|A0A804HLH6|A0A804HLH6_HUMAN,tr|A0A804HJH7|A0A804HJH7_HUMAN,tr|F2Z2B9|F2Z2B9_HUMAN,tr|R4GMM4|R4GMM4_HUMAN,tr|A0A804HK74|A0A804HK74_HUMAN,tr|A0A804HL95|A0A804HL95_HUMAN,tr|A0A804HJ08|A0A804HJ08_HUMAN,tr|A0A804HJQ4|A0A804HJQ4_HUMAN,tr|A0A804HJS9|A0A804HJS9_HUMAN,tr|A0A804HL05|A0A804HL05_HUMAN,tr|A0A804HI27|A0A804HI27_HUMAN" 12 1461.7464 1.58 79102 9031 3 1461.745499 488.2561 Gamma-tubulin complex component 2 OS=Homo sapiens OX=9606 GN=TUBGCP2 PE=1 SV=2 8.29 1911.3 - 879705 - - - -0.5877 - 2.138 0.451 - 220.7 1 2 0 -0.0009 14 0 0 0 1.74E+07 1.10E+07 - - - 5.5873 0.9998 221125_WJC_METTL3_EV_vs_WT_F06.09032.09032.2 1.77E-05 24-Nov R.GAGNC[160.03]PEC[160.03]GTPLR.K sp|P51948|MAT1_HUMAN 1 1387.5973 2.55 79103 9032 2 1387.60002 694.8059 CDK-activating kinase assembly factor MAT1 OS=Homo sapiens OX=9606 GN=MNAT1 PE=1 SV=1 5.99 1911.4 - 776864 - - - 1.9826 - 2.355 0.554 - 326.8 1 2 0 0.0028 13 0 0 0 1.40E+07 5.50E+06 - - - 5.3303 0.9999 221125_WJC_METTL3_EV_vs_WT_F06.09034.09034.3 0.000339 Nov-52 K.YAGGNPVC[160.03]VRPTPK.W "sp|Q15004|PAF15_HUMAN,tr|H0YMA4|H0YMA4_HUMAN,tr|A0A0U1RQM0|A0A0U1RQM0_HUMAN,tr|H0YKX3|H0YKX3_HUMAN" 4 1514.7664 0.62 79105 9034 3 1514.768195 505.9294 PCNA-associated factor OS=Homo sapiens OX=9606 GN=PCLAF PE=1 SV=1 9.31 1911.6 - 279969 - - - 1.1962 - 2.212 0.391 - 91.7 1 2 0 0.0018 14 0 0 0 3.31E+06 5.32E+06 - - - 5.0086 0.9998 221125_WJC_METTL3_EV_vs_WT_F06.09035.09035.2 0.00145 20-Oct R.NLNGHSIGQYR[166.11].L "sp|P50579|MAP2_HUMAN,tr|F8VQZ7|F8VQZ7_HUMAN,tr|F8VRR3|F8VRR3_HUMAN" 3 1267.6297 0.61 79106 9035 2 1267.630717 634.8221 Methionine aminopeptidase 2 OS=Homo sapiens OX=9606 GN=METAP2 PE=1 SV=1 8.75 1911.7 - 190717 - - - 0.7999 - 1.968 0.438 - 344 1 2 0 0.001 11 0 0 0 1.68E+06 2.75E+06 - - - 4.1072 0.9951 221125_WJC_METTL3_EV_vs_WT_F06.09036.09036.2 0.0311 24-Aug R.VITNFNSAHDTDR.N "sp|Q08188|TGM3_HUMAN,tr|A0A494C0J7|A0A494C0J7_HUMAN" 2 1488.6957 1.62 79107 9036 2 1488.700023 745.3551 Protein-glutamine gamma-glutamyltransferase E OS=Homo sapiens OX=9606 GN=TGM3 PE=1 SV=4 5.21 1911.9 - 164936 - - - 2.8904 - 1.352 0.33 - 137.8 1 2 0 0.0043 13 0 0 0 1.15E+07 7.08E+06 - - - 2.2511 0.9994 221125_WJC_METTL3_EV_vs_WT_F06.09040.09040.3 0.0207 14/44 K.LIQNLDANHDGR.L sp|Q96FQ6|S10AG_HUMAN 1 1364.6797 21.37 79109 9040 3 1364.680961 455.9005 Protein S100-A16 OS=Homo sapiens OX=9606 GN=S100A16 PE=1 SV=1 5.21 1912.3 - 8.90E+06 - - - 0.9416 - 2.237 0.271 - 274.6 1 2 0 0.0013 12 0 0 0 1.32E+08 6.17E+06 - - - 3.7927 0.9995 221125_WJC_METTL3_EV_vs_WT_F06.09043.09043.3 2.93E-05 Oct-36 K.FEENQKEFER.V "sp|Q9BZJ0|CRNL1_HUMAN,tr|Q5JY65|Q5JY65_HUMAN" 2 1354.6153 1.27 79112 9043 3 1354.612513 452.5457 Crooked neck-like protein 1 OS=Homo sapiens OX=9606 GN=CRNKL1 PE=1 SV=4 4.49 1912.5 - 1.58E+06 - - - -2.0899 - 1.775 0.504 - 76.2 1 2 1 -0.0028 10 0 0 0 2.16E+07 1.70E+07 - - - 5.8341 1 221125_WJC_METTL3_EV_vs_WT_F06.09044.09044.3 6.17E-07 13/44 R.LVSHLNNYASQR.E "sp|Q9Y5J3|HEY1_HUMAN,tr|E5RHK6|E5RHK6_HUMAN,tr|A0A6I8PRS3|A0A6I8PRS3_HUMAN,tr|A0A6I8PRC2|A0A6I8PRC2_HUMAN,tr|B4DEI9|B4DEI9_HUMAN" 5 1400.7161 1.02 79113 9044 3 1400.717407 467.9126 Hairy\enhancer-of-split related with YRPW motif protein 1 OS=Homo sapiens OX=9606 GN=HEY1 PE=1 SV=1 8.75 1912.5 - 1.23E+06 - - - 0.9609 - 2.504 0.5 - 253.3 1 2 0 0.0013 12 0 0 0 8.80E+07 8.62E+07 - - - 6.6584 0.9998 221125_WJC_METTL3_EV_vs_WT_F06.09045.09045.2 4.52E-07 24-Oct K.NLSNPEMTSGSDK.L sp|O15226|NKRF_HUMAN 1 1378.6035 2.7 79114 9045 2 1378.605267 690.309 NF-kappa-B-repressing factor OS=Homo sapiens OX=9606 GN=NKRF PE=1 SV=2 4.37 1912.7 - 416895 - - - 1.3115 - 1.969 0.572 - 229.2 1 2 0 0.0018 13 0 0 0 7.39E+06 2.74E+06 - - - 5.0041 0.9941 221125_WJC_METTL3_EV_vs_WT_F06.09046.09046.2 0.207 16-Jun K.QDSGHLDLR[166.11].N "sp|Q86U44|MTA70_HUMAN,tr|B4E349|B4E349_HUMAN,tr|F5H6D8|F5H6D8_HUMAN,tr|B4DTN4|B4DTN4_HUMAN" 4 1049.5129 0.94 79115 9046 2 1049.512537 525.7637 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 5.21 1912.8 - 393629 - - - -0.3849 - 1.332 0.151 - 109.2 1 2 0 -0.0004 9 0 0 0 7.64E+07 8.13E+07 - - - 0.9855 1 221125_WJC_METTL3_EV_vs_WT_F06.09049.09049.2 4.89E-07 13/24 R.LQSIGTENTEENR[166.11].R "sp|P04075|ALDOA_HUMAN,tr|H3BR04|H3BR04_HUMAN,tr|H3BMQ8|H3BMQ8_HUMAN,tr|H3BQN4|H3BQN4_HUMAN,tr|H3BUH7|H3BUH7_HUMAN,tr|J3KPS3|J3KPS3_HUMAN,tr|H3BPS8|H3BPS8_HUMAN" 7 1499.7091 1.94 79118 9049 2 1499.713292 750.8618 Fructose-bisphosphate aldolase A OS=Homo sapiens OX=9606 GN=ALDOA PE=1 SV=2 4.25 1913.2 - 194838 - - - 2.7719 - 2.568 0.585 - 640.6 1 2 0 0.0042 13 0 0 0 2.00E+07 1.03E+07 - - - 5.7811 0.9857 221125_WJC_METTL3_EV_vs_WT_F06.09052.09052.3 0.196 Sep-48 K.AIEK[136.11]GETLPTEAR[166.11].F sp|Q8IZH2|XRN1_HUMAN 1 1431.7688 1.36 79119 9052 3 1431.769138 478.2636 5'-3' exoribonuclease 1 OS=Homo sapiens OX=9606 GN=XRN1 PE=1 SV=1 4.79 1913.6 - 1.34E+06 - - - 0.2165 - 2.175 0.169 - 139.6 1 2 1 0.0003 13 0 0 0 3.81E+07 2.81E+07 - - - 2.5308 0.9995 221125_WJC_METTL3_EV_vs_WT_F06.09053.09053.2 0.00684 22-Oct K.LIQNLDANHDGR.L sp|Q96FQ6|S10AG_HUMAN 1 1364.6797 999 79120 9053 2 1364.680897 683.3471 Protein S100-A16 OS=Homo sapiens OX=9606 GN=S100A16 PE=1 SV=1 5.21 1913.7 - 592341 - - - 0.8947 - 1.637 0.395 - 198.4 1 2 0 0.0012 12 0 0 0 1.05E+07 0.00E+00 - - - 3.2549 0.9999 221125_WJC_METTL3_EV_vs_WT_F06.09054.09054.3 2.01E-05 13/44 R.LVSHLNNYASQR[166.11].E "sp|Q9Y5J3|HEY1_HUMAN,tr|E5RHK6|E5RHK6_HUMAN,tr|A0A6I8PRS3|A0A6I8PRS3_HUMAN,tr|A0A6I8PRC2|A0A6I8PRC2_HUMAN,tr|B4DEI9|B4DEI9_HUMAN" 5 1410.7243 0.99 79121 9054 3 1410.723798 471.2487 Hairy\enhancer-of-split related with YRPW motif protein 1 OS=Homo sapiens OX=9606 GN=HEY1 PE=1 SV=1 8.75 1913.8 - 2.50E+06 - - - -0.3778 - 2.076 0.42 - 226.1 1 2 0 -0.0005 12 0 0 0 8.80E+07 8.89E+07 - - - 5.2471 0.9997 221125_WJC_METTL3_EV_vs_WT_F06.09056.09056.2 2.40E-05 24-Sep K.EADASPASAGIC[160.03]R.L "sp|Q9BW27|NUP85_HUMAN,tr|J3QLD4|J3QLD4_HUMAN,tr|J3QLV0|J3QLV0_HUMAN,tr|J3QL54|J3QL54_HUMAN" 4 1303.5827 1.04 79123 9056 2 1303.58441 652.7986 Nuclear pore complex protein Nup85 OS=Homo sapiens OX=9606 GN=NUP85 PE=1 SV=1 4.37 1913.9 - 461333 - - - 1.3394 - 1.762 0.491 - 161.8 1 2 0 0.0017 13 0 0 0 9.45E+06 9.05E+06 - - - 4.1208 0.9998 221125_WJC_METTL3_EV_vs_WT_F06.09058.09058.2 0.000134 22-Nov R.LVSHLNNYASQR.E "sp|Q9Y5J3|HEY1_HUMAN,tr|E5RHK6|E5RHK6_HUMAN,tr|A0A6I8PRS3|A0A6I8PRS3_HUMAN,tr|A0A6I8PRC2|A0A6I8PRC2_HUMAN,tr|B4DEI9|B4DEI9_HUMAN" 5 1400.7161 1.31 79125 9058 2 1400.717691 701.3653 Hairy\enhancer-of-split related with YRPW motif protein 1 OS=Homo sapiens OX=9606 GN=HEY1 PE=1 SV=1 8.75 1914.2 - 274846 - - - 1.1637 - 2.097 0.459 - 474.9 1 2 0 0.0016 12 0 0 0 1.14E+07 8.68E+06 - - - 4.3791 1 221125_WJC_METTL3_EV_vs_WT_F06.09059.09059.2 1.31E-08 13/28 R.MDAPASGSAC[160.03]SGLNK[136.11].Q sp|Q9UKJ3|GPTC8_HUMAN 1 1472.6479 1.24 79126 9059 2 1472.653387 737.3312 G patch domain-containing protein 8 OS=Homo sapiens OX=9606 GN=GPATCH8 PE=1 SV=2 5.59 1914.3 - 214765 - - - 3.7164 - 2.293 0.668 - 179.1 1 2 0 0.0055 15 0 0 0 6.52E+06 5.27E+06 - - - 6.0134 0.9998 221125_WJC_METTL3_EV_vs_WT_F06.09062.09062.3 0.000447 Sep-36 R.GYDDRDYYSR.S "sp|P62995|TRA2B_HUMAN,tr|H7BXF3|H7BXF3_HUMAN,tr|H7C2L4|H7C2L4_HUMAN" 3 1308.5371 1.43 79127 9062 3 1308.536824 437.1863 Transformer-2 protein homolog beta OS=Homo sapiens OX=9606 GN=TRA2B PE=1 SV=1 4.43 1914.7 - 1.79E+06 - - - -0.2063 - 1.624 0.535 - 113.2 1 2 1 -0.0003 10 0 0 0 1.57E+08 1.10E+08 - - - 5.9207 0.9997 221125_WJC_METTL3_EV_vs_WT_F06.09065.09065.2 0.000997 20-Nov R.KLVNTINPGAR.F sp|Q92900|RENT1_HUMAN 1 1181.6881 1.1 79130 9065 2 1181.690596 591.8513 Regulator of nonsense transcripts 1 OS=Homo sapiens OX=9606 GN=UPF1 PE=1 SV=2 11 1915 - 670704 - - - 2.1495 - 2.463 0.432 - 468.5 1 2 0 0.0025 11 0 0 0 1.30E+07 1.18E+07 - - - 4.6694 1 221125_WJC_METTL3_EV_vs_WT_F06.09070.09070.2 4.73E-06 13/22 K.TGC[160.03]ETVDAVQER[166.11].V "sp|O94901|SUN1_HUMAN,tr|H0Y742|H0Y742_HUMAN,tr|E9PHI4|E9PHI4_HUMAN,tr|H0Y6N5|H0Y6N5_HUMAN,tr|H7C2K3|H7C2K3_HUMAN" 5 1373.6121 7.2 79135 9070 2 1374.605658 687.8133 SUN domain-containing protein 1 OS=Homo sapiens OX=9606 GN=SUN1 PE=1 SV=4 4.14 1915.7 - 418506 - - - 723.344 - 2.729 0.593 - 786 1 2 0 0.9936 12 0 0 0 1.04E+07 1.45E+06 - - - 5.7504 0.9998 221125_WJC_METTL3_EV_vs_WT_F06.09073.09073.2 0.00308 18-Sep R.GPLPLSSQHR.G "sp|P43243|MATR3_HUMAN,tr|A8MXP9|A8MXP9_HUMAN,tr|D6R991|D6R991_HUMAN,tr|A0A0R4J2E8|A0A0R4J2E8_HUMAN,tr|D6R8Z5|D6R8Z5_HUMAN,tr|D6REM6|D6REM6_HUMAN" 6 1090.5883 1.37 79137 9073 2 1090.588671 546.3014 Matrin-3 OS=Homo sapiens OX=9606 GN=MATR3 PE=1 SV=2 9.76 1916 - 4.11E+06 - - - 0.3017 - 1.975 0.484 - 308.3 1 2 0 0.0003 10 0 0 0 1.68E+08 1.23E+08 - - - 4.5154 0.9999 221125_WJC_METTL3_EV_vs_WT_F06.09075.09075.3 0.000531 13/44 K.YKPESEELTAER.L "sp|P07237|PDIA1_HUMAN,tr|A0A7P0TA97|A0A7P0TA97_HUMAN,tr|A0A7P0T8C0|A0A7P0T8C0_HUMAN,tr|H7BZ94|H7BZ94_HUMAN,tr|B3KTQ9|B3KTQ9_HUMAN,tr|A0A7P0TA71|A0A7P0TA71_HUMAN,tr|I3L4M2|I3L4M2_HUMAN,tr|A0A7P0T9D6|A0A7P0T9D6_HUMAN,tr|A0A7P0T9K9|A0A7P0T9K9_HUMAN,tr|H0Y3Z3|H0Y3Z3_HUMAN,tr|A0A7P0TA35|A0A7P0TA35_HUMAN,tr|I3L514|I3L514_HUMAN,tr|A0A7P0TB26|A0A7P0TB26_HUMAN,tr|A0A7P0T9U6|A0A7P0T9U6_HUMAN,tr|I3L0S0|I3L0S0_HUMAN,tr|I3L3P5|I3L3P5_HUMAN,tr|A0A7P0T8J3|A0A7P0T8J3_HUMAN,tr|A0A7P0T8X1|A0A7P0T8X1_HUMAN" 18 1450.694 1.5 79139 9075 3 1450.695991 484.5719 Protein disulfide-isomerase OS=Homo sapiens OX=9606 GN=P4HB PE=1 SV=3 4.49 1916.1 - 4.11E+06 - - - 1.38 - 2.327 0.403 - 240.2 1 2 0 0.002 12 0 0 0 9.44E+07 6.30E+07 - - - 5.3735 0.9998 221125_WJC_METTL3_EV_vs_WT_F06.09076.09076.3 0.000134 Sep-36 R.GYDDR[166.11]DYYSR[166.11].S "sp|P62995|TRA2B_HUMAN,tr|H7BXF3|H7BXF3_HUMAN,tr|H7C2L4|H7C2L4_HUMAN" 3 1328.5536 1.5 79140 9076 3 1328.55452 443.8585 Transformer-2 protein homolog beta OS=Homo sapiens OX=9606 GN=TRA2B PE=1 SV=1 4.43 1916.2 - 3.71E+06 - - - 0.6669 - 1.654 0.545 - 115.3 1 2 1 0.0009 10 0 0 0 1.66E+08 1.10E+08 - - - 6.0855 1 221125_WJC_METTL3_EV_vs_WT_F06.09080.09080.2 8.33E-07 14/22 R.LVSHLNNYASQR[166.11].E "sp|Q9Y5J3|HEY1_HUMAN,tr|E5RHK6|E5RHK6_HUMAN,tr|A0A6I8PRS3|A0A6I8PRS3_HUMAN,tr|A0A6I8PRC2|A0A6I8PRC2_HUMAN,tr|B4DEI9|B4DEI9_HUMAN" 5 1410.7243 1.31 79144 9080 2 1410.723457 706.3694 Hairy\enhancer-of-split related with YRPW motif protein 1 OS=Homo sapiens OX=9606 GN=HEY1 PE=1 SV=1 8.75 1916.6 - 625601 - - - -0.6195 - 2.523 0.579 - 865.1 1 2 0 -0.0009 12 0 0 0 1.14E+07 8.68E+06 - - - 5.7522 1 221125_WJC_METTL3_EV_vs_WT_F06.09083.09083.2 4.07E-11 13/24 R.TPC[160.03]NAGTFSQPEK[136.11].V "sp|O43684|BUB3_HUMAN,tr|J3QT28|J3QT28_HUMAN,tr|J3QSX4|J3QSX4_HUMAN" 3 1443.6544 0.58 79147 9083 2 1443.658549 722.8345 Mitotic checkpoint protein BUB3 OS=Homo sapiens OX=9606 GN=BUB3 PE=1 SV=1 5.66 1917 - 328886 - - - 2.8885 - 2.728 0.672 - 450.5 1 2 0 0.0042 13 0 0 0 1.54E+07 2.68E+07 - - - 6.5788 0.9904 221125_WJC_METTL3_EV_vs_WT_F06.09084.09084.2 0.000877 18-Dec R.GYDDRDYYSR.S "sp|P62995|TRA2B_HUMAN,tr|H7BXF3|H7BXF3_HUMAN,tr|H7C2L4|H7C2L4_HUMAN" 3 1308.5371 1.57 79148 9084 2 1308.532167 655.2758 Transformer-2 protein homolog beta OS=Homo sapiens OX=9606 GN=TRA2B PE=1 SV=1 4.43 1917.2 - 325274 - - - -3.7653 - 1.98 0.554 - 308.8 1 2 1 -0.0049 10 0 0 0 2.17E+07 1.39E+07 - - - 5.038 0.9997 221125_WJC_METTL3_EV_vs_WT_F06.09085.09085.2 0.0007 22-Aug K.YK[136.11]PESEELTAER[166.11].L "sp|P07237|PDIA1_HUMAN,tr|A0A7P0TA97|A0A7P0TA97_HUMAN,tr|A0A7P0T8C0|A0A7P0T8C0_HUMAN,tr|H7BZ94|H7BZ94_HUMAN,tr|B3KTQ9|B3KTQ9_HUMAN,tr|A0A7P0TA71|A0A7P0TA71_HUMAN,tr|I3L4M2|I3L4M2_HUMAN,tr|A0A7P0T9D6|A0A7P0T9D6_HUMAN,tr|A0A7P0T9K9|A0A7P0T9K9_HUMAN,tr|H0Y3Z3|H0Y3Z3_HUMAN,tr|A0A7P0TA35|A0A7P0TA35_HUMAN,tr|I3L514|I3L514_HUMAN,tr|A0A7P0TB26|A0A7P0TB26_HUMAN,tr|A0A7P0T9U6|A0A7P0T9U6_HUMAN,tr|I3L0S0|I3L0S0_HUMAN,tr|I3L3P5|I3L3P5_HUMAN,tr|A0A7P0T8J3|A0A7P0T8J3_HUMAN,tr|A0A7P0T8X1|A0A7P0T8X1_HUMAN" 18 1468.7165 1.54 79149 9085 2 1468.717575 735.3655 Protein disulfide-isomerase OS=Homo sapiens OX=9606 GN=P4HB PE=1 SV=3 4.49 1917.3 - 324340 - - - 0.7598 - 1.695 0.484 - 121.7 1 2 0 0.0011 12 0 0 0 1.09E+07 7.07E+06 - - - 4.0039 0.9999 221125_WJC_METTL3_EV_vs_WT_F06.09088.09088.2 0.0062 22-Dec K.EAQELSQNSAIK[136.11].Q sp|Q9NR30|DDX21_HUMAN 1 1324.6714 1.02 79151 9088 2 1324.671601 663.343 Nucleolar RNA helicase 2 OS=Homo sapiens OX=9606 GN=DDX21 PE=1 SV=5 4.53 1917.6 - 2.83E+06 - - - 0.1449 - 2.458 0.424 - 540.1 1 2 0 0.0002 12 0 0 0 6.98E+07 6.81E+07 - - - 4.5389 0.9944 221125_WJC_METTL3_EV_vs_WT_F06.09089.09089.3 0.00388 Dec-40 F.VTFDDHDSVDK.L "sp|Q32P51|RA1L2_HUMAN,sp|P09651|ROA1_HUMAN,tr|A0A7I2YQX9|A0A7I2YQX9_HUMAN,tr|F8VZ49|F8VZ49_HUMAN,tr|A0A7I2V3R8|A0A7I2V3R8_HUMAN,tr|F8VTQ5|F8VTQ5_HUMAN,tr|F8W6I7|F8W6I7_HUMAN,tr|H0YH80|H0YH80_HUMAN,tr|A0A7I2V2L6|A0A7I2V2L6_HUMAN,tr|A0A7I2V3W0|A0A7I2V3W0_HUMAN,tr|A0A7I2V5U9|A0A7I2V5U9_HUMAN,tr|A0A2R8Y4L2|A0A2R8Y4L2_HUMAN" 12 1276.5572 1.52 79152 9089 3 1276.556817 426.5263 Heterogeneous nuclear ribonucleoprotein A1-like 2 OS=Homo sapiens OX=9606 GN=HNRNPA1L2 PE=2 SV=2 4.13 1917.6 - 1.47E+06 - - - -0.2695 - 1.922 0.488 - 176.7 1 1 0 -0.0003 11 0 0 0 2.98E+07 1.96E+07 - - - 5.8367 0.9998 221125_WJC_METTL3_EV_vs_WT_F06.09090.09090.2 0.00091 16-Nov K.R[166.11]AEFTVETR[166.11].S "sp|P21333|FLNA_HUMAN,tr|A0A7P0NMY4|A0A7P0NMY4_HUMAN,tr|Q60FE5|Q60FE5_HUMAN,tr|A0A7I2V3E6|A0A7I2V3E6_HUMAN,tr|A0A087WWY3|A0A087WWY3_HUMAN,tr|F8WE98|F8WE98_HUMAN" 6 1127.5838 1.41 79153 9090 2 1127.584247 564.7992 Filamin-A OS=Homo sapiens OX=9606 GN=FLNA PE=1 SV=4 6.14 1917.8 - 1.34E+06 - - - 0.3858 - 2.182 0.348 - 269.2 1 2 0 0.0004 9 0 0 0 2.00E+07 1.42E+07 - - - 3.8685 0.9957 221125_WJC_METTL3_EV_vs_WT_F06.09091.09091.3 0.000513 Dec-40 F.VTFDDHDSVDK[136.11].L "sp|Q32P51|RA1L2_HUMAN,sp|P09651|ROA1_HUMAN,tr|A0A7I2YQX9|A0A7I2YQX9_HUMAN,tr|F8VZ49|F8VZ49_HUMAN,tr|A0A7I2V3R8|A0A7I2V3R8_HUMAN,tr|F8VTQ5|F8VTQ5_HUMAN,tr|F8W6I7|F8W6I7_HUMAN,tr|H0YH80|H0YH80_HUMAN,tr|A0A7I2V2L6|A0A7I2V2L6_HUMAN,tr|A0A7I2V3W0|A0A7I2V3W0_HUMAN,tr|A0A7I2V5U9|A0A7I2V5U9_HUMAN,tr|A0A2R8Y4L2|A0A2R8Y4L2_HUMAN" 12 1284.5714 1.64 79154 9091 3 1284.571795 429.1977 Heterogeneous nuclear ribonucleoprotein A1-like 2 OS=Homo sapiens OX=9606 GN=HNRNPA1L2 PE=2 SV=2 4.13 1917.8 - 1.17E+06 - - - 0.3379 - 2.239 0.475 - 228.5 1 1 0 0.0004 11 0 0 0 3.42E+07 2.08E+07 - - - 6.1255 0.9997 221125_WJC_METTL3_EV_vs_WT_F06.09093.09093.2 1.45E-05 22-Sep R.HVGDLGNVTADK.D "sp|P00441|SODC_HUMAN,tr|H7BYH4|H7BYH4_HUMAN" 2 1224.6099 0.06 79156 9093 2 1224.607109 613.3122 Superoxide dismutase [Cu-Zn] OS=Homo sapiens OX=9606 GN=SOD1 PE=1 SV=2 5.21 1918.1 - 477051 - - - -2.2505 - 2 0.551 - 138.7 1 2 0 -0.0028 12 0 0 0 6.65E+06 1.05E+08 - - - 4.9336 1 221125_WJC_METTL3_EV_vs_WT_F06.09096.09096.2 7.43E-11 13/24 R.TPC[160.03]NAGTFSQPEK.V "sp|O43684|BUB3_HUMAN,tr|J3QT28|J3QT28_HUMAN,tr|J3QSX4|J3QSX4_HUMAN" 3 1435.6402 0.58 79159 9096 2 1435.644069 718.8274 Mitotic checkpoint protein BUB3 OS=Homo sapiens OX=9606 GN=BUB3 PE=1 SV=1 5.66 1918.4 - 333569 - - - 2.7096 - 2.762 0.718 - 491.2 1 2 0 0.0039 13 0 0 0 1.54E+07 2.68E+07 - - - 6.9504 0.9999 221125_WJC_METTL3_EV_vs_WT_F06.09100.09100.3 2.74E-05 Dec-36 R.VDTC[160.03]HTPFGK[136.11].R "sp|P52701|MSH6_HUMAN,tr|A0A494C0M1|A0A494C0M1_HUMAN,tr|A0A087WWJ1|A0A087WWJ1_HUMAN" 3 1168.5426 0.64 79161 9100 3 1168.540447 390.5215 DNA mismatch repair protein Msh6 OS=Homo sapiens OX=9606 GN=MSH6 PE=1 SV=2 6.71 1919 - 1.00E+06 - - - -1.8801 - 2.094 0.447 - 242.6 1 2 0 -0.0022 10 0 0 0 1.22E+07 1.92E+07 - - - 5.6814 0.9982 221125_WJC_METTL3_EV_vs_WT_F06.09103.09103.2 0.0107 18-Jul R.VDTC[160.03]HTPFGK[136.11].R "sp|P52701|MSH6_HUMAN,tr|A0A494C0M1|A0A494C0M1_HUMAN,tr|A0A087WWJ1|A0A087WWJ1_HUMAN" 3 1168.5426 0.16 79164 9103 2 1168.54177 585.2786 DNA mismatch repair protein Msh6 OS=Homo sapiens OX=9606 GN=MSH6 PE=1 SV=2 6.71 1919.4 - 348280 - - - -0.7479 - 1.28 0.302 - 131.9 1 2 0 -0.0009 10 0 0 0 1.97E+06 1.25E+07 - - - 1.9604 0.9996 221125_WJC_METTL3_EV_vs_WT_F06.09110.09110.2 8.87E-05 20-Oct R.LQEDPNYSPQR[166.11].F "sp|P46379|BAG6_HUMAN,tr|A0A7I2V508|A0A7I2V508_HUMAN,tr|H0Y710|H0Y710_HUMAN,tr|H0Y4L1|H0Y4L1_HUMAN,tr|A0A7P0MQS5|A0A7P0MQS5_HUMAN,tr|A0A0G2JL47|A0A0G2JL47_HUMAN,tr|A0A024RCR6|A0A024RCR6_HUMAN,tr|A0A0G2JK23|A0A0G2JK23_HUMAN" 8 1355.6345 2.12 79169 9110 2 1355.633206 678.8245 Large proline-rich protein BAG6 OS=Homo sapiens OX=9606 GN=BAG6 PE=1 SV=2 4.37 1920.3 - 357493 - - - -0.9641 - 2.028 0.344 - 312.5 1 2 0 -0.0013 11 0 0 0 1.49E+08 7.06E+07 - - - 3.4941 0.9995 221125_WJC_METTL3_EV_vs_WT_F06.09118.09118.2 0.000898 20-Nov R.LQEDPNYSPQR.F "sp|P46379|BAG6_HUMAN,tr|A0A7I2V508|A0A7I2V508_HUMAN,tr|H0Y710|H0Y710_HUMAN,tr|H0Y4L1|H0Y4L1_HUMAN,tr|A0A7P0MQS5|A0A7P0MQS5_HUMAN,tr|A0A0G2JL47|A0A0G2JL47_HUMAN,tr|A0A024RCR6|A0A024RCR6_HUMAN,tr|A0A0G2JK23|A0A0G2JK23_HUMAN" 8 1345.6262 2.12 79175 9118 2 1345.62552 673.8204 Large proline-rich protein BAG6 OS=Homo sapiens OX=9606 GN=BAG6 PE=1 SV=2 4.37 1921.2 - 566361 - - - -0.5373 - 2.018 0.301 - 305.5 1 2 0 -0.0007 11 0 0 0 1.49E+08 7.06E+07 - - - 3.1633 0.9919 221125_WJC_METTL3_EV_vs_WT_F06.09120.09120.2 3.01E-06 24-Dec F.STAADGQTQVEIK[136.11].V "sp|P38646|GRP75_HUMAN,tr|A0A7I2V2S7|A0A7I2V2S7_HUMAN,tr|A0A7I2V2G2|A0A7I2V2G2_HUMAN,tr|A0A7I2V3F7|A0A7I2V3F7_HUMAN,tr|A0A7I2YQB2|A0A7I2YQB2_HUMAN,tr|D6RCD7|D6RCD7_HUMAN" 6 1354.682 1.09 79177 9120 2 1354.682946 678.3483 "Stress-70 protein, mitochondrial OS=Homo sapiens OX=9606 GN=HSPA9 PE=1 SV=2" 4.37 1921.5 - 422595 - - - 0.7175 - 2.459 0.484 - 461.2 1 1 0 0.001 13 0 0 0 2.60E+07 2.38E+07 - - - 4.9248 0.8274 221125_WJC_METTL3_EV_vs_WT_F06.09121.09121.2 0.851 16-Jun K.K[136.11]INIMNEEK[136.11].V sp|Q8N0T1|RBIS_HUMAN 1 1133.6085 2.53 79178 9121 2 1133.603586 567.8115 Ribosomal biogenesis factor OS=Homo sapiens OX=9606 GN=RBIS PE=1 SV=4 6.14 1921.6 - 344624 - - - -4.3745 - 1.138 0.135 - 111.6 2 2 0 -0.005 9 0 0 0 1.24E+07 4.88E+06 - - - 0.2761 0.9981 221125_WJC_METTL3_EV_vs_WT_F06.09123.09123.2 0.0066 13/20 K.DVLAHQVPNAK.K "sp|Q9NZM5|NOP53_HUMAN,tr|M0QZ34|M0QZ34_HUMAN,tr|M0QX73|M0QX73_HUMAN" 3 1190.6408 2.43 79180 9123 2 1190.635288 596.3277 Ribosome biogenesis protein NOP53 OS=Homo sapiens OX=9606 GN=NOP53 PE=1 SV=2 6.74 1921.9 - 325585 - - - -4.6051 - 2.561 0.422 - 835 1 2 0 -0.0055 11 0 0 0 7.14E+06 2.94E+06 - - - 4.7002 0.9894 221125_WJC_METTL3_EV_vs_WT_F06.09124.09124.3 0.117 Aug-52 R.VLPYHPAQPGQAAK[136.11].K "sp|Q8IZ52|CHSS2_HUMAN,tr|F8W6H2|F8W6H2_HUMAN" 2 1483.8027 1.36 79181 9124 3 1483.804286 495.6082 Chondroitin sulfate synthase 2 OS=Homo sapiens OX=9606 GN=CHPF PE=1 SV=2 8.57 1922 - 300129 - - - 1.0702 - 1.228 0.248 - 47.2 1 2 0 0.0016 14 0 0 0 5.93E+06 4.37E+06 - - - 1.8503 0.9999 221125_WJC_METTL3_EV_vs_WT_F06.09128.09128.3 0.000432 Nov-44 K.LYC[160.03]ANGHTFQAK.R sp|P41743|KPCI_HUMAN 1 1408.6558 1.09 79183 9128 3 1408.655167 470.5592 Protein kinase C iota type OS=Homo sapiens OX=9606 GN=PRKCI PE=1 SV=2 8.21 1922.5 - 1.58E+06 - - - -0.4281 - 2.045 0.455 - 98.1 1 2 0 -0.0006 12 0 0 0 2.94E+07 2.70E+07 - - - 5.5956 0.998 221125_WJC_METTL3_EV_vs_WT_F06.09130.09130.2 1.44E-06 22-Nov K.VGGTSDVEVNEK[136.11].K "sp|P10809|CH60_HUMAN,tr|A0A7I2V2X6|A0A7I2V2X6_HUMAN,tr|A0A7I2YQK6|A0A7I2YQK6_HUMAN,tr|A0A7I2V599|A0A7I2V599_HUMAN" 4 1240.6027 1.16 79185 9130 2 1240.599158 621.3086 "60 kDa heat shock protein, mitochondrial OS=Homo sapiens OX=9606 GN=HSPD1 PE=1 SV=2" 4.14 1922.8 - 748162 - - - -2.8236 - 2.428 0.222 - 498.3 1 2 0 -0.0035 12 0 0 0 2.21E+07 1.90E+07 - - - 3.0136 0.9997 221125_WJC_METTL3_EV_vs_WT_F06.09131.09131.2 0.053 16-Sep K.KINIMNEEK.V sp|Q8N0T1|RBIS_HUMAN 1 1117.5801 2.29 79186 9131 2 1117.579134 559.7973 Ribosomal biogenesis factor OS=Homo sapiens OX=9606 GN=RBIS PE=1 SV=4 6.14 1922.9 - 745956 - - - -0.9046 - 2.091 0.356 - 233.4 1 2 0 -0.001 9 0 0 0 1.27E+07 5.55E+06 - - - 3.8041 0.9924 221125_WJC_METTL3_EV_vs_WT_F06.09135.09135.2 1.5 16-Jun K.EDFAEVC[160.03]KR.E sp|Q9BU76|MMTA2_HUMAN 1 1152.5234 1.27 79190 9135 2 1152.52295 577.269 Multiple myeloma tumor-associated protein 2 OS=Homo sapiens OX=9606 GN=MMTAG2 PE=1 SV=1 4.68 1923.3 - 242423 - - - -0.354 - 1.21 0.165 - 138.9 1 2 0 -0.0004 9 0 0 0 4.57E+06 3.60E+06 - - - 0.811 0.9996 221125_WJC_METTL3_EV_vs_WT_F06.09138.09138.3 0.000197 13/48 K.VGTLVGEDK[136.11]YGNK[136.11].Y "sp|Q9UI09|NDUAC_HUMAN,tr|H0YID5|H0YID5_HUMAN,tr|F8VRD8|F8VRD8_HUMAN,tr|H0YIT1|H0YIT1_HUMAN,tr|A0A804HJF8|A0A804HJF8_HUMAN,tr|A0A804HK60|A0A804HK60_HUMAN,tr|A0A804HHX9|A0A804HHX9_HUMAN" 7 1394.7376 1.58 79191 9138 3 1394.736571 465.9198 NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 12 OS=Homo sapiens OX=9606 GN=NDUFA12 PE=1 SV=1 6.04 1923.7 - 1.25E+06 - - - -0.77 - 2.396 0.389 - 276.6 1 2 1 -0.0011 13 0 0 0 2.48E+07 1.57E+07 - - - 5.2458 0.9797 221125_WJC_METTL3_EV_vs_WT_F06.09139.09139.2 0.0382 24-Aug K.DTDGGPKEEESPV.- sp|P53985|MOT1_HUMAN 1 1358.5838 1.02 79192 9139 2 1358.582783 680.2992 Monocarboxylate transporter 1 OS=Homo sapiens OX=9606 GN=SLC16A1 PE=1 SV=3 3.83 1923.9 - 458060 - - - -0.7258 - 1.283 0.303 - 103.8 1 2 1 -0.001 13 0 0 0 1.70E+07 1.67E+07 - - - 1.9182 0.9988 221125_WJC_METTL3_EV_vs_WT_F06.09140.09140.2 0.00247 22-Dec K.AVVVC[160.03]PK[136.11]DEDYK[136.11].Q "sp|Q00839|HNRPU_HUMAN,tr|A0A1W2PQL0|A0A1W2PQL0_HUMAN,tr|A0A1W2PPL4|A0A1W2PPL4_HUMAN,tr|A0A1W2PQ74|A0A1W2PQ74_HUMAN,tr|Q5RI18|Q5RI18_HUMAN,tr|A0A1W2PP35|A0A1W2PP35_HUMAN,tr|A0A1W2PPS1|A0A1W2PPS1_HUMAN,tr|A0A1W2PRZ7|A0A1W2PRZ7_HUMAN,tr|A0A1W2PPH7|A0A1W2PPH7_HUMAN,tr|A0A1W2PQD4|A0A1W2PQD4_HUMAN,tr|A0A1W2PP34|A0A1W2PP34_HUMAN,tr|A0A1X7SBS1|A0A1X7SBS1_HUMAN" 12 1437.7145 0.99 79193 9140 2 1437.713795 719.8645 Heterogeneous nuclear ribonucleoprotein U OS=Homo sapiens OX=9606 GN=HNRNPU PE=1 SV=6 4.56 1924 - 1.01E+06 - - - -0.4674 - 2.57 0.479 - 563 1 2 1 -0.0007 12 0 0 0 5.41E+07 5.46E+07 - - - 5.0623 0.947 221125_WJC_METTL3_EV_vs_WT_F06.09143.09143.2 0.0599 24-Jul K.DTDGGPK[136.11]EEESPV.- sp|P53985|MOT1_HUMAN 1 1366.598 1.03 79196 9143 2 1366.59984 684.3063 Monocarboxylate transporter 1 OS=Homo sapiens OX=9606 GN=SLC16A1 PE=1 SV=3 3.83 1924.4 - 401107 - - - 1.3691 - 1.288 0.238 - 79.5 1 2 1 0.0019 13 0 0 0 1.67E+07 1.63E+07 - - - 1.4478 0.9998 221125_WJC_METTL3_EV_vs_WT_F06.09145.09145.2 0.000444 18-Sep R.GPLPLSSQHR[166.11].G "sp|P43243|MATR3_HUMAN,tr|A8MXP9|A8MXP9_HUMAN,tr|D6R991|D6R991_HUMAN,tr|A0A0R4J2E8|A0A0R4J2E8_HUMAN,tr|D6R8Z5|D6R8Z5_HUMAN,tr|D6REM6|D6REM6_HUMAN" 6 1100.5966 1.43 79197 9145 2 1100.596404 551.3056 Matrin-3 OS=Homo sapiens OX=9606 GN=MATR3 PE=1 SV=2 9.76 1924.6 - 1.03E+06 - - - -0.189 - 1.952 0.452 - 305.9 1 2 0 -0.0002 10 0 0 0 4.35E+07 3.05E+07 - - - 4.2464 0.9998 221125_WJC_METTL3_EV_vs_WT_F06.09150.09150.2 4.74E-05 16-Oct K.ESEFDDEPK.F "sp|Q9Y2W1|TR150_HUMAN,tr|A0A3B3ITZ9|A0A3B3ITZ9_HUMAN" 2 1094.4404 3.12 79201 9150 2 1094.441733 548.2275 Thyroid hormone receptor-associated protein 3 OS=Homo sapiens OX=9606 GN=THRAP3 PE=1 SV=2 3.83 1925.2 - 800049 - - - 1.218 - 1.874 0.583 - 427.5 1 2 0 0.0013 9 0 0 0 3.73E+08 1.19E+08 - - - 5.1637 0.9948 221125_WJC_METTL3_EV_vs_WT_F06.09160.09160.2 3.73E-07 18-Nov Y.MFQYDSTHGK[136.11].F sp|P04406|G3P_HUMAN 1 1220.5376 0.98 79209 9160 2 1220.538073 611.2761 Glyceraldehyde-3-phosphate dehydrogenase OS=Homo sapiens OX=9606 GN=GAPDH PE=1 SV=3 6.49 1926.2 - 1.16E+06 - - - 0.4219 - 2.092 0.623 - 436.8 1 1 0 0.0005 10 0 0 0 2.11E+08 2.17E+08 - - - 5.7026 0.9997 221125_WJC_METTL3_EV_vs_WT_F06.09166.09166.2 0.00011 18-Aug R.DNTNEIYSGK[136.11].F "sp|P05556|ITB1_HUMAN,tr|H7C4N8|H7C4N8_HUMAN,tr|A0A7I2V2F9|A0A7I2V2F9_HUMAN,tr|H7C4K3|H7C4K3_HUMAN,tr|E7EUI6|E7EUI6_HUMAN,tr|A0A7I2V348|A0A7I2V348_HUMAN,tr|C9JPK5|C9JPK5_HUMAN" 7 1147.5237 1.05 79215 9166 2 1147.521553 574.7691 Integrin beta-1 OS=Homo sapiens OX=9606 GN=ITGB1 PE=1 SV=2 4.37 1927 - 333986 - - - -1.8553 - 1.902 0.478 - 292.1 1 2 0 -0.0021 10 0 0 0 2.13E+07 2.04E+07 - - - 4.3654 0.9999 221125_WJC_METTL3_EV_vs_WT_F06.09169.09169.2 0.000158 13/24 K.GPGEVAGTVTGQK[136.11].R "sp|Q86U44|MTA70_HUMAN,tr|F5H6D8|F5H6D8_HUMAN,tr|H0YFV6|H0YFV6_HUMAN,tr|B4DTN4|B4DTN4_HUMAN" 4 1207.6288 0.03 79216 9169 2 1207.628239 604.8217 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 6 1927.4 - 2.14E+08 - - - -0.4778 - 2.663 0.557 - 750.7 1 2 0 -0.0006 13 0 0 0 6.22E+08 2.37E+10 - - - 5.6686 0.8793 221125_WJC_METTL3_EV_vs_WT_F06.09170.09170.3 0.0214 Sep-36 Y.MFQYDSTHGK.F sp|P04406|G3P_HUMAN 1 1212.5234 0.94 79217 9170 3 1212.522177 405.1817 Glyceraldehyde-3-phosphate dehydrogenase OS=Homo sapiens OX=9606 GN=GAPDH PE=1 SV=3 6.49 1927.4 - 1.56E+07 - - - -0.974 - 1.625 0.284 - 114.3 1 1 0 -0.0012 10 0 0 0 9.96E+08 1.06E+09 - - - 3.1239 0.9993 221125_WJC_METTL3_EV_vs_WT_F06.09172.09172.3 0.00937 Oct-32 K.EDFAEVC[160.03]KR.E sp|Q9BU76|MMTA2_HUMAN 1 1152.5234 0.73 79219 9172 3 1152.520971 385.1817 Multiple myeloma tumor-associated protein 2 OS=Homo sapiens OX=9606 GN=MMTAG2 PE=1 SV=1 4.68 1927.6 - 867706 - - - -2.0711 - 1.775 0.338 - 153 1 2 0 -0.0024 9 0 0 0 7.87E+06 1.07E+07 - - - 4.037 1 221125_WJC_METTL3_EV_vs_WT_F06.09173.09173.2 2.65E-08 22-Nov K.EAMEDGEIDGNK.V "sp|P19338|NUCL_HUMAN,tr|A0A7I2V699|A0A7I2V699_HUMAN,tr|A0A7I2V3F3|A0A7I2V3F3_HUMAN,tr|A0A7I2V428|A0A7I2V428_HUMAN,tr|H7BY16|H7BY16_HUMAN,tr|C9JLB1|C9JLB1_HUMAN" 6 1306.5347 1.27 79220 9173 2 1306.533619 654.2746 Nucleolin OS=Homo sapiens OX=9606 GN=NCL PE=1 SV=3 3.83 1927.7 - 826964 - - - -0.8358 - 2.373 0.675 - 464 1 2 0 -0.0011 12 0 0 0 2.92E+07 2.30E+07 - - - 6.2999 0.9995 221125_WJC_METTL3_EV_vs_WT_F06.09174.09174.2 0.0183 20-Nov K.EQELNQSISEK[136.11].E "sp|Q15643|TRIPB_HUMAN,tr|H0YJ97|H0YJ97_HUMAN" 2 1311.6398 1.36 79221 9174 2 1311.637755 656.8272 Thyroid receptor-interacting protein 11 OS=Homo sapiens OX=9606 GN=TRIP11 PE=1 SV=3 4.25 1927.9 - 815276 - - - -1.5401 - 2.084 0.354 - 456.2 1 2 0 -0.002 11 0 0 0 3.27E+08 2.40E+08 - - - 3.6414 0.9997 221125_WJC_METTL3_EV_vs_WT_F06.09178.09178.2 0.000333 16-Sep K.ESEFDDEPK[136.11].F "sp|Q9Y2W1|TR150_HUMAN,tr|A0A3B3ITZ9|A0A3B3ITZ9_HUMAN" 2 1102.4546 3.14 79223 9178 2 1102.455987 552.2346 Thyroid hormone receptor-associated protein 3 OS=Homo sapiens OX=9606 GN=THRAP3 PE=1 SV=2 3.83 1928.4 - 748817 - - - 1.2581 - 1.521 0.497 - 322.9 1 2 0 0.0014 9 0 0 0 3.75E+08 1.19E+08 - - - 3.9247 0.9999 221125_WJC_METTL3_EV_vs_WT_F06.09184.09184.3 2.17E-06 14/44 K.AVVVC[160.03]PKDEDYK.Q "sp|Q00839|HNRPU_HUMAN,tr|A0A1W2PQL0|A0A1W2PQL0_HUMAN,tr|A0A1W2PPL4|A0A1W2PPL4_HUMAN,tr|A0A1W2PQ74|A0A1W2PQ74_HUMAN,tr|Q5RI18|Q5RI18_HUMAN,tr|A0A1W2PP35|A0A1W2PP35_HUMAN,tr|A0A1W2PPS1|A0A1W2PPS1_HUMAN,tr|A0A1W2PRZ7|A0A1W2PRZ7_HUMAN,tr|A0A1W2PPH7|A0A1W2PPH7_HUMAN,tr|A0A1W2PQD4|A0A1W2PQD4_HUMAN,tr|A0A1W2PP34|A0A1W2PP34_HUMAN,tr|A0A1X7SBS1|A0A1X7SBS1_HUMAN" 12 1421.6861 1.03 79228 9184 3 1421.684999 474.9026 Heterogeneous nuclear ribonucleoprotein U OS=Homo sapiens OX=9606 GN=HNRNPU PE=1 SV=6 4.56 1929 - 1.97E+07 - - - -0.7512 - 2.237 0.575 - 246.5 1 2 1 -0.0011 12 0 0 0 5.50E+08 5.32E+08 - - - 7.1821 0.9998 221125_WJC_METTL3_EV_vs_WT_F06.09186.09186.3 0.00103 14/44 K.QIDQLSK[136.11]DEVGK[136.11].L "sp|Q15643|TRIPB_HUMAN,tr|H0YJ97|H0YJ97_HUMAN" 2 1374.7326 12.8 79229 9186 3 1374.730286 459.2515 Thyroid receptor-interacting protein 11 OS=Homo sapiens OX=9606 GN=TRIP11 PE=1 SV=3 4.56 1929.2 - 2.23E+06 - - - -1.6534 - 2.701 0.443 - 286.9 1 2 1 -0.0023 12 0 0 0 4.38E+08 3.42E+07 - - - 6.2326 0.9987 221125_WJC_METTL3_EV_vs_WT_F06.09187.09187.2 0.00036 20-Nov K.EQELNQSISEK.E "sp|Q15643|TRIPB_HUMAN,tr|H0YJ97|H0YJ97_HUMAN" 2 1303.6256 1.36 79230 9187 2 1303.63016 652.8201 Thyroid receptor-interacting protein 11 OS=Homo sapiens OX=9606 GN=TRIP11 PE=1 SV=3 4.25 1929.3 - 2.50E+06 - - - 3.5171 - 2.004 0.434 - 432.1 1 2 0 0.0046 11 0 0 0 3.27E+08 2.40E+08 - - - 4.1256 0.9938 221125_WJC_METTL3_EV_vs_WT_F06.09189.09189.2 3.35E-07 16-Sep M.FQYDSTHGK[136.11].F sp|P04406|G3P_HUMAN 1 1089.4971 0.89 79232 9189 2 1089.496719 545.7558 Glyceraldehyde-3-phosphate dehydrogenase OS=Homo sapiens OX=9606 GN=GAPDH PE=1 SV=3 6.74 1929.4 - 1.47E+06 - - - -0.3249 - 1.753 0.608 - 215.2 1 1 0 -0.0004 9 0 0 0 3.35E+07 3.78E+07 - - - 5.1555 1 221125_WJC_METTL3_EV_vs_WT_F06.09190.09190.2 7.68E-06 15/28 K.TDEGVAAPVSGGAAR[166.11].L "sp|Q6BDS2|URFB1_HUMAN,tr|H7C1J4|H7C1J4_HUMAN" 2 1366.6716 0.25 79233 9190 2 1366.67016 684.3431 UHRF1-binding protein 1 OS=Homo sapiens OX=9606 GN=UHRF1BP1 PE=1 SV=1 4.37 1929.5 - 1.36E+06 - - - -1.0734 - 2.692 0.594 - 545.2 1 2 0 -0.0015 15 0 0 0 8.72E+06 3.55E+07 - - - 5.8625 0.999 221125_WJC_METTL3_EV_vs_WT_F06.09193.09193.2 0.0102 18-Jul R.FEPYANPTK[136.11]R[166.11].Y "sp|P52272|HNRPM_HUMAN,tr|M0R019|M0R019_HUMAN,tr|M0R0Y6|M0R0Y6_HUMAN,tr|M0R0N3|M0R0N3_HUMAN,tr|A0A087X0X3|A0A087X0X3_HUMAN,tr|M0QYQ7|M0QYQ7_HUMAN,tr|M0R2T0|M0R2T0_HUMAN" 7 1239.6367 0.33 79236 9193 2 1239.638635 620.8256 Heterogeneous nuclear ribonucleoprotein M OS=Homo sapiens OX=9606 GN=HNRNPM PE=1 SV=3 8.59 1929.9 - 428806 - - - 1.5674 - 1.358 0.402 - 188.6 1 2 0 0.0019 10 0 0 0 9.66E+06 2.93E+07 - - - 2.8637 0.9937 221125_WJC_METTL3_EV_vs_WT_F06.09196.09196.3 0.0329 Sep-44 K.IKGEELSEANVR.L "sp|Q14203|DCTN1_HUMAN,tr|A0A804CDA6|A0A804CDA6_HUMAN,tr|E7EX90|E7EX90_HUMAN,tr|A0A7P0Z4C3|A0A7P0Z4C3_HUMAN" 4 1343.7045 2.03 79237 9196 3 1343.702721 448.9088 Dynactin subunit 1 OS=Homo sapiens OX=9606 GN=DCTN1 PE=1 SV=3 4.79 1930.3 - 1.05E+07 - - - -1.3195 - 1.746 0.279 - 150.2 1 2 1 -0.0018 12 0 0 0 1.11E+09 5.47E+08 - - - 3.1949 0.9856 221125_WJC_METTL3_EV_vs_WT_F06.09197.09197.2 6.11E-05 16-Jul M.FQYDSTHGK.F sp|P04406|G3P_HUMAN 1 1081.4829 0.9 79238 9197 2 1081.482726 541.7487 Glyceraldehyde-3-phosphate dehydrogenase OS=Homo sapiens OX=9606 GN=GAPDH PE=1 SV=3 6.74 1930.4 - 1.65E+06 - - - -0.1359 - 1.512 0.485 - 121.2 1 1 0 -0.0001 9 0 0 0 3.35E+07 3.73E+07 - - - 3.8192 0.9997 221125_WJC_METTL3_EV_vs_WT_F06.09199.09199.2 0.00107 16-Oct R.SGDTHLFDK.V "sp|Q8NCE2|MTMRE_HUMAN,tr|B4DQK9|B4DQK9_HUMAN" 2 1018.472 6.8 79240 9199 2 1018.471042 510.2433 Myotubularin-related protein 14 OS=Homo sapiens OX=9606 GN=MTMR14 PE=1 SV=2 5.19 1930.7 - 608580 - - - -0.9151 - 1.702 0.406 - 436 1 2 0 -0.0009 9 0 0 0 2.59E+07 3.81E+06 - - - 3.578 0.7744 221125_WJC_METTL3_EV_vs_WT_F06.09205.09205.2 0.0789 20-Jun Q.DNYNEEVADLK.L "sp|Q8N3C0|ASCC3_HUMAN,tr|J3KNJ4|J3KNJ4_HUMAN,tr|E5RFZ0|E5RFZ0_HUMAN" 3 1308.5834 1.55 79244 9205 2 1308.586227 655.299 Activating signal cointegrator 1 complex subunit 3 OS=Homo sapiens OX=9606 GN=ASCC3 PE=1 SV=3 3.92 1931.4 - 6.18E+06 - - - 2.1795 - 1.123 0.338 - 81.7 1 1 0 0.0029 11 0 0 0 5.10E+08 3.28E+08 - - - 1.8504 0.9965 221125_WJC_METTL3_EV_vs_WT_F06.09206.09206.2 0.00221 13/22 K.IK[136.11]GEELSEANVR[166.11].L "sp|Q14203|DCTN1_HUMAN,tr|A0A804CDA6|A0A804CDA6_HUMAN,tr|E7EX90|E7EX90_HUMAN,tr|A0A7P0Z4C3|A0A7P0Z4C3_HUMAN" 4 1361.727 2.08 79245 9206 2 1361.72524 681.8708 Dynactin subunit 1 OS=Homo sapiens OX=9606 GN=DCTN1 PE=1 SV=3 4.79 1931.5 - 1.50E+06 - - - -1.266 - 2.05 0.403 - 277.2 1 2 1 -0.0017 12 0 0 0 1.95E+08 9.40E+07 - - - 3.9058 0.9988 221125_WJC_METTL3_EV_vs_WT_F06.09208.09208.3 0.00277 Oct-44 R.YLAEVAC[160.03]GDDR[166.11]K[136.11].Q "sp|P27348|1433T_HUMAN,tr|E9PG15|E9PG15_HUMAN" 2 1413.6677 1.29 79247 9208 3 1413.66586 472.2299 14-3-3 protein theta OS=Homo sapiens OX=9606 GN=YWHAQ PE=1 SV=1 4.56 1931.6 - 1.40E+06 - - - -1.3256 - 1.563 0.314 - 78 1 2 0 -0.0019 12 0 0 0 3.95E+07 3.07E+07 - - - 3.2782 0.9869 221125_WJC_METTL3_EV_vs_WT_F06.09209.09209.3 0.459 16/48 K.RPLVTPQAAPEPK.R sp|Q9Y6X8|ZHX2_HUMAN 1 1402.7932 3.2 79248 9209 3 1402.793736 468.605 Zinc fingers and homeoboxes protein 2 OS=Homo sapiens OX=9606 GN=ZHX2 PE=1 SV=1 8.75 1931.8 - 852445 - - - 0.3472 - 1.462 0.186 - 199 1 2 0 0.0005 13 0 0 0 4.20E+07 1.32E+07 - - - 1.6433 0.9964 221125_WJC_METTL3_EV_vs_WT_F06.09215.09215.2 6.65E-05 13/22 K.IKGEELSEANVR.L "sp|Q14203|DCTN1_HUMAN,tr|A0A804CDA6|A0A804CDA6_HUMAN,tr|E7EX90|E7EX90_HUMAN,tr|A0A7P0Z4C3|A0A7P0Z4C3_HUMAN" 4 1343.7045 2.08 79252 9215 2 1343.702088 672.8595 Dynactin subunit 1 OS=Homo sapiens OX=9606 GN=DCTN1 PE=1 SV=3 4.79 1932.5 - 4.92E+06 - - - -1.7906 - 1.969 0.471 - 335.6 1 2 1 -0.0024 12 0 0 0 1.95E+08 9.40E+07 - - - 4.3017 0.9726 221125_WJC_METTL3_EV_vs_WT_F06.09221.09221.2 0.0994 16-Aug T.KFETEQALR.L "sp|Q04695|K1C17_HUMAN,sp|P08727|K1C19_HUMAN,tr|C9JM50|C9JM50_HUMAN,tr|F5GWP8|F5GWP8_HUMAN" 4 1120.5877 999 79258 9221 2 1120.587206 561.3011 "Keratin, type I cytoskeletal 17 OS=Homo sapiens OX=9606 GN=KRT17 PE=1 SV=2" 6.14 1933.2 - 231605 - - - -0.4167 - 1.841 0.311 - 253.4 1 1 0 -0.0005 9 0 0 0 2.58E+07 0.00E+00 - - - 3.1036 0.9963 221125_WJC_METTL3_EV_vs_WT_F06.09233.09233.3 0.00615 Sep-44 K.IK[136.11]GEELSEANVR[166.11].L "sp|Q14203|DCTN1_HUMAN,tr|A0A804CDA6|A0A804CDA6_HUMAN,tr|E7EX90|E7EX90_HUMAN,tr|A0A7P0Z4C3|A0A7P0Z4C3_HUMAN" 4 1361.727 2.03 79266 9233 3 1361.724587 454.9163 Dynactin subunit 1 OS=Homo sapiens OX=9606 GN=DCTN1 PE=1 SV=3 4.79 1934.3 - 2.98E+07 - - - -1.7456 - 1.887 0.312 - 145.9 1 2 1 -0.0024 12 0 0 0 1.11E+09 5.47E+08 - - - 3.7779 0.9802 221125_WJC_METTL3_EV_vs_WT_F06.09237.09237.2 0.000695 14-Aug E.PYANPTK[136.11]R[166.11].Y "sp|P52272|HNRPM_HUMAN,tr|M0R019|M0R019_HUMAN,tr|M0R0Y6|M0R0Y6_HUMAN,tr|M0R0N3|M0R0N3_HUMAN,tr|A0A087X0X3|A0A087X0X3_HUMAN,tr|M0QYQ7|M0QYQ7_HUMAN,tr|M0R2T0|M0R2T0_HUMAN" 7 963.5257 2.21 79270 9237 2 963.526137 482.7701 Heterogeneous nuclear ribonucleoprotein M OS=Homo sapiens OX=9606 GN=HNRNPM PE=1 SV=3 10.01 1934.7 - 661690 - - - 0.4691 - 1.608 0.414 - 198 1 1 0 0.0005 8 0 0 0 3.52E+07 1.59E+07 - - - 3.5312 0.9991 221125_WJC_METTL3_EV_vs_WT_F06.09241.09241.2 0.00663 14-Aug K.FETEQALR.L "sp|Q04695|K1C17_HUMAN,sp|P08727|K1C19_HUMAN,tr|C9JM50|C9JM50_HUMAN,tr|F5GWP8|F5GWP8_HUMAN" 4 992.4927 999 79272 9241 2 992.48964 497.2536 "Keratin, type I cytoskeletal 17 OS=Homo sapiens OX=9606 GN=KRT17 PE=1 SV=2" 4.53 1935.2 - 2.55E+06 - - - -3.0932 - 1.713 0.474 - 200.4 1 2 0 -0.0031 8 0 0 0 6.18E+07 0.00E+00 - - - 4.1643 0.9997 221125_WJC_METTL3_EV_vs_WT_F06.09245.09245.3 0.000532 Nov-36 R.LC[160.03]SVHFQGGR.K sp|Q96EK4|THA11_HUMAN 1 1159.5557 1.24 79276 9245 3 1159.553122 387.5258 THAP domain-containing protein 11 OS=Homo sapiens OX=9606 GN=THAP11 PE=1 SV=2 8.26 1935.7 - 504023 - - - -2.1896 - 2.116 0.374 - 139 1 2 0 -0.0025 10 0 0 0 1.93E+07 1.55E+07 - - - 4.898 0.9998 221125_WJC_METTL3_EV_vs_WT_F06.09247.09247.3 2.03E-05 Dec-44 K.AVVVC[160.03]PK[136.11]DEDYK[136.11].Q "sp|Q00839|HNRPU_HUMAN,tr|A0A1W2PQL0|A0A1W2PQL0_HUMAN,tr|A0A1W2PPL4|A0A1W2PPL4_HUMAN,tr|A0A1W2PQ74|A0A1W2PQ74_HUMAN,tr|Q5RI18|Q5RI18_HUMAN,tr|A0A1W2PP35|A0A1W2PP35_HUMAN,tr|A0A1W2PPS1|A0A1W2PPS1_HUMAN,tr|A0A1W2PRZ7|A0A1W2PRZ7_HUMAN,tr|A0A1W2PPH7|A0A1W2PPH7_HUMAN,tr|A0A1W2PQD4|A0A1W2PQD4_HUMAN,tr|A0A1W2PP34|A0A1W2PP34_HUMAN,tr|A0A1X7SBS1|A0A1X7SBS1_HUMAN" 12 1437.7145 1.03 79277 9247 3 1437.712174 480.2454 Heterogeneous nuclear ribonucleoprotein U OS=Homo sapiens OX=9606 GN=HNRNPU PE=1 SV=6 4.56 1935.9 - 8.44E+06 - - - -1.5949 - 2.33 0.492 - 174 1 2 1 -0.0023 12 0 0 0 5.50E+08 5.32E+08 - - - 6.3693 0.8304 221125_WJC_METTL3_EV_vs_WT_F06.09255.09255.3 0.11 Sep-32 R.R[166.11]EEEGIQLR[166.11].K "sp|O60684|IMA7_HUMAN,sp|O15131|IMA6_HUMAN,sp|P52294|IMA5_HUMAN,tr|C9JWD9|C9JWD9_HUMAN,tr|S4R3E5|S4R3E5_HUMAN,tr|C9JYI4|C9JYI4_HUMAN,tr|C9J352|C9J352_HUMAN,tr|C9J4U1|C9J4U1_HUMAN,tr|F2Z3G4|F2Z3G4_HUMAN,tr|Q5TD90|Q5TD90_HUMAN" 10 1148.6053 0.001 79282 9255 3 1148.599001 383.8757 Importin subunit alpha-7 OS=Homo sapiens OX=9606 GN=KPNA6 PE=1 SV=1 4.79 1936.7 - 752447 - - - -5.4631 - 1.758 0.146 - 116.6 1 2 0 -0.0063 9 0 0 0 0.00E+00 1.15E+07 - - - 1.8663 0.9999 221125_WJC_METTL3_EV_vs_WT_F06.09259.09259.3 3.40E-05 Nov-36 R.FEPYANPTK[136.11]R[166.11].Y "sp|P52272|HNRPM_HUMAN,tr|M0R019|M0R019_HUMAN,tr|M0R0Y6|M0R0Y6_HUMAN,tr|M0R0N3|M0R0N3_HUMAN,tr|A0A087X0X3|A0A087X0X3_HUMAN,tr|M0QYQ7|M0QYQ7_HUMAN,tr|M0R2T0|M0R2T0_HUMAN" 7 1239.6367 0.3 79284 9259 3 1239.634357 414.2195 Heterogeneous nuclear ribonucleoprotein M OS=Homo sapiens OX=9606 GN=HNRNPM PE=1 SV=3 8.59 1937.2 - 4.92E+06 - - - -1.8836 - 2.008 0.5 - 158.7 1 2 0 -0.0023 10 0 0 0 5.18E+07 1.71E+08 - - - 6.1498 0.9801 221125_WJC_METTL3_EV_vs_WT_F06.09260.09260.3 0.0525 Nov-36 R.YRNPVSQC[160.03]MR.G "sp|Q13148|TADBP_HUMAN,tr|A0A087WX29|A0A087WX29_HUMAN,tr|K7EJ99|K7EJ99_HUMAN,tr|G3V162|G3V162_HUMAN,tr|A0A0A0MSV7|A0A0A0MSV7_HUMAN,tr|A0A087WYY0|A0A087WYY0_HUMAN,tr|K7EN94|K7EN94_HUMAN,tr|A0A0A0N0M3|A0A0A0N0M3_HUMAN,tr|B1AKP7|B1AKP7_HUMAN,tr|K7EJM5|K7EJM5_HUMAN,tr|A0A087X260|A0A087X260_HUMAN" 11 1309.602 1.47 79285 9260 3 1309.599665 437.5413 TAR DNA-binding protein 43 OS=Homo sapiens OX=9606 GN=TARDBP PE=1 SV=1 9.5 1937.3 - 1.87E+06 - - - -1.7524 - 1.649 0.232 - 157.9 1 2 1 -0.0023 10 0 0 0 8.49E+07 5.77E+07 - - - 2.5866 0.9987 221125_WJC_METTL3_EV_vs_WT_F06.09267.09267.3 0.000256 Sep-36 R.TKFETEQALR.L "sp|Q04695|K1C17_HUMAN,sp|P08727|K1C19_HUMAN,tr|C9JM50|C9JM50_HUMAN,tr|F5GWP8|F5GWP8_HUMAN" 4 1221.6354 346.65 79289 9267 3 1221.633175 408.2191 "Keratin, type I cytoskeletal 17 OS=Homo sapiens OX=9606 GN=KRT17 PE=1 SV=2" 5.81 1938.1 - 3.13E+08 - - - -1.7812 - 2.16 0.349 - 199.7 1 2 1 -0.0022 10 0 0 0 7.04E+09 2.03E+07 - - - 4.6795 1 221125_WJC_METTL3_EV_vs_WT_F06.09271.09271.2 1.14E-06 15/24 K.GPGEVAGTVTGQK.R "sp|Q86U44|MTA70_HUMAN,tr|F5H6D8|F5H6D8_HUMAN,tr|H0YFV6|H0YFV6_HUMAN,tr|B4DTN4|B4DTN4_HUMAN" 4 1199.6146 0.03 79292 9271 2 1199.614261 600.8146 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 6 1938.5 - 7.82E+06 - - - -0.2959 - 2.918 0.609 - 969.2 1 2 0 -0.0004 13 0 0 0 6.20E+08 2.37E+10 - - - 6.2875 1 221125_WJC_METTL3_EV_vs_WT_F06.09273.09273.3 1.74E-05 18/56 R.VGQAVDVVGQAGK[136.11]PK[136.11].T sp|Q13200|PSMD2_HUMAN 1 1467.838 0.53 79293 9273 3 1467.836902 490.2866 26S proteasome non-ATPase regulatory subunit 2 OS=Homo sapiens OX=9606 GN=PSMD2 PE=1 SV=3 8.56 1938.7 - 1.08E+06 - - - -0.7664 - 3.582 0.54 - 484.3 1 2 0 -0.0011 15 0 0 0 4.79E+07 9.03E+07 - - - 7.8895 0.9964 221125_WJC_METTL3_EV_vs_WT_F06.09274.09274.2 7.76E-06 16/28 K.AINGPTSASGDDISK.L "sp|P51114|FXR1_HUMAN,tr|H7C4S4|H7C4S4_HUMAN,tr|B4DXZ6|B4DXZ6_HUMAN" 3 1431.6842 1.19 79294 9274 2 1431.67553 716.8494 Fragile X mental retardation syndrome-related protein 1 OS=Homo sapiens OX=9606 GN=FXR1 PE=1 SV=3 4.21 1938.9 - 1.04E+06 - - - -6.0223 - 2.616 0.547 - 349.9 1 2 0 -0.0086 15 0 0 0 1.46E+08 1.22E+08 - - - 5.4427 0.9995 221125_WJC_METTL3_EV_vs_WT_F06.09276.09276.2 0.000568 20-Oct R.EATQNSSQFMK.H "sp|Q9Y6J9|TAF6L_HUMAN,tr|E9PP94|E9PP94_HUMAN" 2 1269.566 0.52 79296 9276 2 1269.563716 635.7903 TAF6-like RNA polymerase II p300\CBP-associated factor-associated factor 65 kDa subunit 6L OS=Homo sapiens OX=9606 GN=TAF6L PE=1 SV=1 6.1 1939 - 1.38E+06 - - - -1.7604 - 1.615 0.467 - 320.9 1 2 0 -0.0022 11 0 0 0 3.71E+07 7.16E+07 - - - 3.7863 0.9997 221125_WJC_METTL3_EV_vs_WT_F06.09279.09279.3 0.00047 Oct-36 R.ETSMVHELNR.Y "sp|P61619|S61A1_HUMAN,tr|B4DR61|B4DR61_HUMAN" 2 1214.5714 1.17 79297 9279 3 1214.569475 405.8644 Protein transport protein Sec61 subunit alpha isoform 1 OS=Homo sapiens OX=9606 GN=SEC61A1 PE=1 SV=2 5.4 1939.4 - 2.46E+06 - - - -1.561 - 1.911 0.363 - 228.6 1 2 0 -0.0019 10 0 0 0 6.81E+07 5.81E+07 - - - 4.4779 0.9706 221125_WJC_METTL3_EV_vs_WT_F06.09281.09281.3 0.278 Sep-36 K.AHPPTQILNR.E sp|Q01804|OTUD4_HUMAN 1 1145.6305 1.04 79299 9281 3 1145.628523 382.8841 OTU domain-containing protein 4 OS=Homo sapiens OX=9606 GN=OTUD4 PE=1 SV=4 9.8 1939.7 - 840035 - - - -1.7615 - 1.659 0.125 - 89.1 1 2 0 -0.002 10 0 0 0 2.23E+07 2.15E+07 - - - 1.4114 0.9975 221125_WJC_METTL3_EV_vs_WT_F06.09282.09282.2 0.00549 22-Oct K.TPTSPLSPSSQK[136.11].S sp|Q5VT06|CE350_HUMAN 1 1236.6441 1.75 79300 9282 2 1236.641058 619.3293 Centrosome-associated protein 350 OS=Homo sapiens OX=9606 GN=CEP350 PE=1 SV=1 8.41 1939.8 - 580691 - - - -2.4858 - 1.615 0.307 - 242.6 1 2 0 -0.0031 12 0 0 0 2.19E+07 1.25E+07 - - - 2.5687 0.9999 221125_WJC_METTL3_EV_vs_WT_F06.09289.09289.3 0.000191 13/48 R.LHNAIEGGTQLSR[166.11].A "sp|O60832|DKC1_HUMAN,tr|C9IYT0|C9IYT0_HUMAN,tr|H7C0M1|H7C0M1_HUMAN,tr|H7BZF2|H7BZF2_HUMAN" 4 1404.7349 0.71 79304 9289 3 1404.732105 469.2522 H\ACA ribonucleoprotein complex subunit DKC1 OS=Homo sapiens OX=9606 GN=DKC1 PE=1 SV=3 6.75 1940.5 - 2.80E+06 - - - -1.9869 - 2.384 0.427 - 148.4 1 2 0 -0.0028 13 0 0 0 5.58E+07 7.81E+07 - - - 5.6554 0.9999 221125_WJC_METTL3_EV_vs_WT_F06.09291.09291.2 4.38E-05 20-Oct R.EATQNSSQFMK[136.11].H "sp|Q9Y6J9|TAF6L_HUMAN,tr|E9PP94|E9PP94_HUMAN" 2 1277.5802 1.19 79306 9291 2 1277.5813 639.7974 TAF6-like RNA polymerase II p300\CBP-associated factor-associated factor 65 kDa subunit 6L OS=Homo sapiens OX=9606 GN=TAF6L PE=1 SV=1 6.1 1940.8 - 1.30E+06 - - - 0.8994 - 2.159 0.541 - 533 1 2 0 0.0011 11 0 0 0 2.55E+07 2.14E+07 - - - 5.1185 1 221125_WJC_METTL3_EV_vs_WT_F06.09292.09292.2 1.10E-06 16/22 K.KALAAAGYDVEK.N "sp|P10412|H14_HUMAN,sp|Q02539|H11_HUMAN,sp|P22492|H1T_HUMAN,sp|P16403|H12_HUMAN,sp|P16402|H13_HUMAN" 5 1234.6558 2.07 79307 9292 2 1234.651391 618.3352 Histone H1.4 OS=Homo sapiens OX=9606 GN=H1-4 PE=1 SV=2 6.07 1940.9 - 1.04E+06 - - - -3.5322 - 2.981 0.528 - 572.9 1 2 0 -0.0044 12 0 0 0 1.67E+07 8.04E+06 - - - 5.8134 0.9393 221125_WJC_METTL3_EV_vs_WT_F06.09293.09293.2 0.538 16-Sep R.AQIEDTLR[166.11]R[166.11].D "sp|Q96CT7|CC124_HUMAN,tr|M0R2F5|M0R2F5_HUMAN" 2 1120.6104 1.03 79308 9293 2 1120.613952 561.3125 Coiled-coil domain-containing protein 124 OS=Homo sapiens OX=9606 GN=CCDC124 PE=1 SV=1 6.12 1941 - 1.01E+06 - - - 3.2045 - 1.315 0.09 - 167.2 1 2 0 0.0036 9 0 0 0 3.01E+07 2.92E+07 - - - 0.4968 1 221125_WJC_METTL3_EV_vs_WT_F06.09297.09297.3 1.32E-05 18/56 R.VGQAVDVVGQAGKPK.T sp|Q13200|PSMD2_HUMAN 1 1451.8096 0.53 79310 9297 3 1451.808775 484.9438 26S proteasome non-ATPase regulatory subunit 2 OS=Homo sapiens OX=9606 GN=PSMD2 PE=1 SV=3 8.56 1941.5 - 1.84E+06 - - - -0.5869 - 3.276 0.477 - 468.2 1 2 0 -0.0009 15 0 0 0 4.79E+07 9.04E+07 - - - 6.9542 0.9979 221125_WJC_METTL3_EV_vs_WT_F06.09304.09304.3 0.0347 Sep-36 R.YR[166.11]NPVSQC[160.03]MR[166.11].G "sp|Q13148|TADBP_HUMAN,tr|A0A087WX29|A0A087WX29_HUMAN,tr|K7EJ99|K7EJ99_HUMAN,tr|G3V162|G3V162_HUMAN,tr|A0A0A0MSV7|A0A0A0MSV7_HUMAN,tr|A0A087WYY0|A0A087WYY0_HUMAN,tr|K7EN94|K7EN94_HUMAN,tr|A0A0A0N0M3|A0A0A0N0M3_HUMAN,tr|B1AKP7|B1AKP7_HUMAN,tr|K7EJM5|K7EJM5_HUMAN,tr|A0A087X260|A0A087X260_HUMAN" 11 1329.6185 1.52 79315 9304 3 1329.61685 444.2134 TAR DNA-binding protein 43 OS=Homo sapiens OX=9606 GN=TARDBP PE=1 SV=1 9.5 1942.3 - 1.11E+06 - - - -1.241 - 1.747 0.343 - 127.9 1 2 1 -0.0016 10 0 0 0 8.72E+07 5.74E+07 - - - 3.993 0.9998 221125_WJC_METTL3_EV_vs_WT_F06.09310.09310.2 0.0256 24-Dec R.LHNAIEGGTQLSR[166.11].A "sp|O60832|DKC1_HUMAN,tr|C9IYT0|C9IYT0_HUMAN,tr|H7C0M1|H7C0M1_HUMAN,tr|H7BZF2|H7BZF2_HUMAN" 4 1404.7349 0.24 79319 9310 2 1404.733735 703.3747 H\ACA ribonucleoprotein complex subunit DKC1 OS=Homo sapiens OX=9606 GN=DKC1 PE=1 SV=3 6.75 1943.1 - 1.20E+06 - - - -0.8265 - 2.424 0.414 - 425.8 1 2 0 -0.0012 13 0 0 0 3.08E+06 1.28E+07 - - - 4.3709 0.9923 221125_WJC_METTL3_EV_vs_WT_F06.09312.09312.3 0.000152 16/48 N.SAPSVESHPVLEK[136.11].L sp|Q9BYJ9|YTHD1_HUMAN 1 1386.7234 1.55 79321 9312 3 1386.723695 463.2484 YTH domain-containing family protein 1 OS=Homo sapiens OX=9606 GN=YTHDF1 PE=1 SV=1 5.38 1943.3 - 1.61E+06 - - - 0.1803 - 2.698 0.382 - 338.8 1 1 0 0.0003 13 0 0 0 2.98E+07 1.92E+07 - - - 5.4898 0.9954 221125_WJC_METTL3_EV_vs_WT_F06.09315.09315.2 1.76E-06 22-Nov K.LPQTSDDEKKDF.- sp|Q9GZT3|SLIRP_HUMAN 1 1421.6674 0.96 79324 9315 2 1421.663568 711.841 "SRA stem-loop-interacting RNA-binding protein, mitochondrial OS=Homo sapiens OX=9606 GN=SLIRP PE=1 SV=1" 4.23 1943.6 - 612327 - - - -2.7229 - 2.037 0.55 - 307.2 1 2 1 -0.0039 12 0 0 0 1.64E+08 1.70E+08 - - - 4.9741 0.9364 221125_WJC_METTL3_EV_vs_WT_F06.09317.09317.3 0.00522 13/56 F.VATDLDTGRPSTTVR.Y sp|Q02413|DSG1_HUMAN 1 1587.8216 999 79326 9317 3 1587.820419 530.2812 Desmoglein-1 OS=Homo sapiens OX=9606 GN=DSG1 PE=1 SV=2 5.93 1943.9 - 499767 - - - -0.7746 - 2.306 0.261 - 284.4 1 1 0 -0.0012 15 0 0 0 1.13E+07 0.00E+00 - - - 3.6297 0.9958 221125_WJC_METTL3_EV_vs_WT_F06.09322.09322.3 0.265 Sep-48 K.EGVVHGVATVAEK.T "sp|P37840|SYUA_HUMAN,tr|A0A669KB41|A0A669KB41_HUMAN,tr|D6RA31|D6RA31_HUMAN,tr|A0A669KBH5|A0A669KBH5_HUMAN,tr|E7EPV7|E7EPV7_HUMAN" 5 1294.6881 1.62 79329 9322 3 1294.687183 432.57 Alpha-synuclein OS=Homo sapiens OX=9606 GN=SNCA PE=1 SV=1 5.4 1944.5 - 8.00E+06 - - - -0.7199 - 1.813 0.196 - 113.7 1 2 0 -0.0009 13 0 0 0 3.97E+08 2.45E+08 - - - 2.3381 1 221125_WJC_METTL3_EV_vs_WT_F06.09323.09323.2 1.99E-06 14/22 K.K[136.11]FAEALGSTEAK[136.11].A "sp|P78347|GTF2I_HUMAN,tr|A0A494C0Q7|A0A494C0Q7_HUMAN,tr|A0A494C1K3|A0A494C1K3_HUMAN" 3 1266.6791 1.25 79330 9323 2 1266.678006 634.3468 General transcription factor II-I OS=Homo sapiens OX=9606 GN=GTF2I PE=1 SV=2 6.14 1944.6 - 7.21E+06 - - - -0.8376 - 3.316 0.523 - 546.5 1 2 0 -0.0011 12 0 0 0 2.04E+08 1.63E+08 - - - 6.0577 1 221125_WJC_METTL3_EV_vs_WT_F06.09324.09324.2 5.90E-05 15/22 K.KFAEALGSTEAK.A "sp|P78347|GTF2I_HUMAN,tr|A0A494C0Q7|A0A494C0Q7_HUMAN,tr|A0A494C1K3|A0A494C1K3_HUMAN" 3 1250.6507 1.25 79331 9324 2 1250.645686 626.3326 General transcription factor II-I OS=Homo sapiens OX=9606 GN=GTF2I PE=1 SV=2 6.14 1944.6 - 8.87E+06 - - - -3.9827 - 3.05 0.563 - 639.2 1 2 0 -0.005 12 0 0 0 2.04E+08 1.63E+08 - - - 6.1319 0.9938 221125_WJC_METTL3_EV_vs_WT_F06.09325.09325.3 0.0965 Jul-48 K.EGVVHGVATVAEK[136.11].T "sp|P37840|SYUA_HUMAN,tr|A0A669KB41|A0A669KB41_HUMAN,tr|D6RA31|D6RA31_HUMAN,tr|A0A669KBH5|A0A669KBH5_HUMAN,tr|E7EPV7|E7EPV7_HUMAN" 5 1302.7023 1.64 79332 9325 3 1302.700575 435.2414 Alpha-synuclein OS=Homo sapiens OX=9606 GN=SNCA PE=1 SV=1 5.4 1944.7 - 5.34E+06 - - - -1.3357 - 1.479 0.233 - 61.5 1 2 0 -0.0017 13 0 0 0 4.01E+08 2.45E+08 - - - 2.1983 0.9973 221125_WJC_METTL3_EV_vs_WT_F06.09328.09328.3 0.183 Oct-40 R.WKEPPGEEPVR.K sp|Q9BUA3|SPNDC_HUMAN 1 1322.6619 0.09 79335 9328 3 1322.660346 441.8946 Spindlin interactor and repressor of chromatin-binding protein OS=Homo sapiens OX=9606 GN=SPINDOC PE=1 SV=3 4.79 1944.8 - 2.77E+06 - - - -1.1749 - 1.771 0.323 - 77.4 1 2 1 -0.0016 11 0 0 0 9.32E+07 1.02E+09 - - - 3.7644 0.9958 221125_WJC_METTL3_EV_vs_WT_F06.09333.09333.2 0.0101 18-Jul K.AHPPTQILNR.E sp|Q01804|OTUD4_HUMAN 1 1145.6305 2.25 79340 9333 2 1145.6272 573.8225 OTU domain-containing protein 4 OS=Homo sapiens OX=9606 GN=OTUD4 PE=1 SV=4 9.8 1945.4 - 422763 - - - -2.9163 - 1.36 0.335 - 191.8 1 2 0 -0.0033 10 0 0 0 3.45E+07 1.53E+07 - - - 2.3725 0.989 221125_WJC_METTL3_EV_vs_WT_F06.09336.09336.2 0.2 18-Oct R.TKFETEQALR.L "sp|Q04695|K1C17_HUMAN,sp|P08727|K1C19_HUMAN,tr|C9JM50|C9JM50_HUMAN,tr|F5GWP8|F5GWP8_HUMAN" 4 1221.6354 999 79342 9336 2 1221.634176 611.825 "Keratin, type I cytoskeletal 17 OS=Homo sapiens OX=9606 GN=KRT17 PE=1 SV=2" 5.81 1945.9 - 902866 - - - -0.9618 - 1.848 0.24 - 295.8 1 2 1 -0.0012 10 0 0 0 2.17E+09 0.00E+00 - - - 2.5274 1 221125_WJC_METTL3_EV_vs_WT_F06.09338.09338.2 1.40E-08 18/24 K.EGVVHGVATVAEK.T "sp|P37840|SYUA_HUMAN,tr|A0A669KB41|A0A669KB41_HUMAN,tr|D6RA31|D6RA31_HUMAN,tr|A0A669KBH5|A0A669KBH5_HUMAN,tr|E7EPV7|E7EPV7_HUMAN" 5 1294.6881 1.61 79343 9338 2 1294.687182 648.3513 Alpha-synuclein OS=Homo sapiens OX=9606 GN=SNCA PE=1 SV=1 5.4 1946.1 - 6.51E+06 - - - -0.7206 - 3.08 0.583 - 1516.6 1 2 0 -0.0009 13 0 0 0 1.78E+08 1.11E+08 - - - 6.2339 1 221125_WJC_METTL3_EV_vs_WT_F06.09340.09340.2 1.71E-08 18/24 K.EGVVHGVATVAEK[136.11].T "sp|P37840|SYUA_HUMAN,tr|A0A669KB41|A0A669KB41_HUMAN,tr|D6RA31|D6RA31_HUMAN,tr|A0A669KBH5|A0A669KBH5_HUMAN,tr|E7EPV7|E7EPV7_HUMAN" 5 1302.7023 1.61 79345 9340 2 1302.701561 652.3584 Alpha-synuclein OS=Homo sapiens OX=9606 GN=SNCA PE=1 SV=1 5.4 1946.2 - 4.53E+06 - - - -0.5788 - 3.069 0.55 - 1287.1 1 2 0 -0.0008 13 0 0 0 1.78E+08 1.11E+08 - - - 5.981 0.9999 221125_WJC_METTL3_EV_vs_WT_F06.09343.09343.3 0.000269 14/48 R.YESHPVC[160.03]ADLQAK.L "sp|Q9NX63|MIC19_HUMAN,tr|C9JRZ6|C9JRZ6_HUMAN" 2 1516.698 2.11 79348 9343 3 1516.69576 506.5733 MICOS complex subunit MIC19 OS=Homo sapiens OX=9606 GN=CHCHD3 PE=1 SV=1 5.32 1946.4 - 1.25E+06 - - - -1.4954 - 2.262 0.458 - 149.2 1 2 0 -0.0023 13 0 0 0 2.63E+07 1.24E+07 - - - 5.8587 1 221125_WJC_METTL3_EV_vs_WT_F06.09344.09344.2 9.14E-06 13/24 K.EVASNSELVQSSR.S "sp|P08779|K1C16_HUMAN,tr|K7ENW6|K7ENW6_HUMAN" 2 1404.6845 999 79349 9344 2 1404.677358 703.3495 "Keratin, type I cytoskeletal 16 OS=Homo sapiens OX=9606 GN=KRT16 PE=1 SV=4" 4.53 1946.5 - 1.03E+06 - - - -5.0744 - 2.745 0.615 - 655.4 1 2 0 -0.0071 13 0 0 0 3.71E+09 0.00E+00 - - - 6.1728 0.9998 221125_WJC_METTL3_EV_vs_WT_F06.09345.09345.2 6.69E-05 22-Dec K.NAWADNANAC[160.03]AK[136.11].Q "sp|Q9NTJ5|SAC1_HUMAN,tr|E9PGZ4|E9PGZ4_HUMAN,tr|A0A5F9ZHN7|A0A5F9ZHN7_HUMAN,tr|C9JV50|C9JV50_HUMAN" 4 1312.571 1.29 79350 9345 2 1312.570602 657.2928 Phosphatidylinositol-3-phosphatase SAC1 OS=Homo sapiens OX=9606 GN=SACM1L PE=1 SV=2 5.83 1946.7 - 610907 - - - -0.291 - 2.16 0.459 - 441.6 1 2 0 -0.0004 12 0 0 0 1.48E+07 1.15E+07 - - - 4.4573 0.9998 221125_WJC_METTL3_EV_vs_WT_F06.09347.09347.3 0.00216 Oct-48 K.GPGEVAGTVTGQK[136.11].R "sp|Q86U44|MTA70_HUMAN,tr|F5H6D8|F5H6D8_HUMAN,tr|H0YFV6|H0YFV6_HUMAN,tr|B4DTN4|B4DTN4_HUMAN" 4 1207.6288 0.09 79351 9347 3 1207.628029 403.5502 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 6 1946.9 - 1.36E+07 - - - -0.6517 - 1.834 0.378 - 165.2 1 2 0 -0.0008 13 0 0 0 9.94E+07 1.11E+09 - - - 4.3985 0.9999 221125_WJC_METTL3_EV_vs_WT_F06.09353.09353.3 1.49E-05 13/36 K.DVPIVHTETK.T "sp|P11171|EPB41_HUMAN,tr|A0A3B3ITP0|A0A3B3ITP0_HUMAN,tr|A0A2U3TZH6|A0A2U3TZH6_HUMAN,tr|A0A2R8Y7Y3|A0A2R8Y7Y3_HUMAN,tr|A0A2R8YD30|A0A2R8YD30_HUMAN" 5 1137.603 0.11 79356 9353 3 1137.60203 380.2083 Protein 4.1 OS=Homo sapiens OX=9606 GN=EPB41 PE=1 SV=4 5.32 1947.4 - 705069 - - - -0.843 - 2.033 0.424 - 164.3 1 2 0 -0.001 10 0 0 0 9.28E+06 8.57E+07 - - - 5.339 0.9999 221125_WJC_METTL3_EV_vs_WT_F06.09357.09357.3 3.55E-07 17/52 K.LQAAVDGPMDKKEE.- "sp|P51572|BAP31_HUMAN,tr|A0A2R8Y5M6|A0A2R8Y5M6_HUMAN" 2 1529.7396 1.11 79358 9357 3 1529.740522 510.9205 B-cell receptor-associated protein 31 OS=Homo sapiens OX=9606 GN=BCAP31 PE=1 SV=3 4.54 1947.9 - 2.24E+06 - - - 0.6295 - 2.96 0.5 - 505.7 1 2 1 0.001 14 0 0 0 1.05E+08 9.48E+07 - - - 6.9982 0.9999 221125_WJC_METTL3_EV_vs_WT_F06.09359.09359.3 0.005 Dec-44 R.SSTPLHSPSPIR[166.11].V "sp|O95817|BAG3_HUMAN,tr|C9JFK9|C9JFK9_HUMAN" 2 1287.6811 0.51 79360 9359 3 1287.681382 430.2343 BAG family molecular chaperone regulator 3 OS=Homo sapiens OX=9606 GN=BAG3 PE=1 SV=3 9.49 1948.1 - 1.43E+06 - - - 0.2423 - 2.133 0.382 - 231.4 1 2 0 0.0003 12 0 0 0 2.98E+07 5.85E+07 - - - 4.8986 0.9999 221125_WJC_METTL3_EV_vs_WT_F06.09360.09360.3 0.000704 16/56 R.LIQSHPESAEDLQEK[136.11].C "sp|Q13813|SPTN1_HUMAN,tr|A0A0D9SF54|A0A0D9SF54_HUMAN,tr|A0A0D9SGF6|A0A0D9SGF6_HUMAN" 3 1730.8566 1.55 79361 9360 3 1730.855961 577.9595 "Spectrin alpha chain, non-erythrocytic 1 OS=Homo sapiens OX=9606 GN=SPTAN1 PE=1 SV=3" 4.4 1948.3 - 991026 - - - -0.3946 - 2.063 0.414 - 213.6 1 2 0 -0.0007 15 0 0 0 6.36E+07 4.09E+07 - - - 5.0451 0.9997 221125_WJC_METTL3_EV_vs_WT_F06.09361.09361.2 0.000862 16-Aug R.DQYEQMAEK.N "sp|P08779|K1C16_HUMAN,tr|K7ENW6|K7ENW6_HUMAN" 2 1140.4757 155.35 79362 9361 2 1140.476051 571.2451 "Keratin, type I cytoskeletal 16 OS=Homo sapiens OX=9606 GN=KRT16 PE=1 SV=4" 4.14 1948.4 - 715960 - - - 0.2736 - 1.704 0.424 - 280 1 2 0 0.0003 9 0 0 0 7.42E+07 4.78E+05 - - - 3.7145 0.9255 221125_WJC_METTL3_EV_vs_WT_F06.09366.09366.2 1.25E-05 13/20 T.PPNGNLSPAPR[166.11].L sp|P48634|PRC2A_HUMAN 1 1128.5915 0.28 79367 9366 2 1128.587608 565.303 Protein PRRC2A OS=Homo sapiens OX=9606 GN=PRRC2A PE=1 SV=3 10.18 1949.1 - 231156 - - - -3.4716 - 1.976 0.423 - 423.6 1 1 0 -0.0039 11 0 0 0 1.96E+06 7.07E+06 - - - 4.0065 1 221125_WJC_METTL3_EV_vs_WT_F06.09371.09371.3 8.69E-08 18/56 R.LIQSHPESAEDLQEK.C "sp|Q13813|SPTN1_HUMAN,tr|A0A0D9SF54|A0A0D9SF54_HUMAN,tr|A0A0D9SGF6|A0A0D9SGF6_HUMAN" 3 1722.8424 1.56 79370 9371 3 1722.841941 575.2881 "Spectrin alpha chain, non-erythrocytic 1 OS=Homo sapiens OX=9606 GN=SPTAN1 PE=1 SV=3" 4.4 1949.6 - 2.59E+06 - - - -0.292 - 2.649 0.521 - 315.6 1 2 0 -0.0005 15 0 0 0 6.37E+07 4.09E+07 - - - 6.8905 1 221125_WJC_METTL3_EV_vs_WT_F06.09372.09372.3 0.00117 14/48 K.EVASNSELVQSSR.S "sp|P08779|K1C16_HUMAN,tr|K7ENW6|K7ENW6_HUMAN" 2 1404.6845 92.94 79371 9372 3 1404.685099 469.2354 "Keratin, type I cytoskeletal 16 OS=Homo sapiens OX=9606 GN=KRT16 PE=1 SV=4" 4.53 1949.6 - 3.50E+06 - - - 0.4364 - 2.633 0.464 - 290.4 1 2 0 0.0006 13 0 0 0 3.18E+08 3.43E+06 - - - 6.3378 0.987 221125_WJC_METTL3_EV_vs_WT_F06.09374.09374.3 0.0227 Nov-44 K.LPQTSDDEK[136.11]KDF.- sp|Q9GZT3|SLIRP_HUMAN 1 1429.6816 - 79373 9374 3 1429.68377 477.5678 "SRA stem-loop-interacting RNA-binding protein, mitochondrial OS=Homo sapiens OX=9606 GN=SLIRP PE=1 SV=1" 4.23 1949.8 - 1.21E+06 - - - 1.4905 - 1.612 0.266 - 67.4 1 2 1 0.0021 12 0 0 0 - - - - - 2.8285 0.9356 221125_WJC_METTL3_EV_vs_WT_F06.09375.09375.2 0.000449 20-Dec L.PQTSDDEK[136.11]K[136.11]DF.- sp|Q9GZT3|SLIRP_HUMAN 1 1324.6118 7.29 79374 9375 2 1324.612429 663.3132 "SRA stem-loop-interacting RNA-binding protein, mitochondrial OS=Homo sapiens OX=9606 GN=SLIRP PE=1 SV=1" 4.23 1949.9 - 686573 - - - 0.4937 - 2.37 0.54 - 397 1 1 1 0.0007 11 0 0 0 9.39E+07 1.29E+07 - - - 5.3636 0.9994 221125_WJC_METTL3_EV_vs_WT_F06.09376.09376.2 0.0016 20-Sep K.ITKPDGIVEER.R "sp|O00165|HAX1_HUMAN,tr|Q5VYD6|Q5VYD6_HUMAN,tr|E9PIQ7|E9PIQ7_HUMAN" 3 1255.6772 1.45 79375 9376 2 1255.675593 628.8459 HCLS1-associated protein X-1 OS=Homo sapiens OX=9606 GN=HAX1 PE=1 SV=2 4.68 1950 - 686398 - - - -1.2925 - 1.58 0.394 - 175.9 1 2 0 -0.0016 11 0 0 0 3.55E+07 2.44E+07 - - - 3.188 0.9992 221125_WJC_METTL3_EV_vs_WT_F06.09377.09377.3 0.00581 Nov-36 K.QQEELDALKK.T sp|O95347|SMC2_HUMAN 1 1200.635 0.82 79376 9377 3 1200.637397 401.2189 Structural maintenance of chromosomes protein 2 OS=Homo sapiens OX=9606 GN=SMC2 PE=1 SV=2 4.68 1950.1 - 603322 - - - 1.9823 - 1.728 0.344 - 132.8 1 2 0 0.0024 10 0 0 0 1.25E+07 1.53E+07 - - - 3.972 0.9998 221125_WJC_METTL3_EV_vs_WT_F06.09378.09378.2 3.63E-06 24-Oct K.QPC[160.03]QPPPVC[160.03]PTPK.C "sp|P22531|SPR2E_HUMAN,sp|P35326|SPR2A_HUMAN,sp|P22532|SPR2D_HUMAN,sp|P35325|SPR2B_HUMAN,sp|Q9BYE4|SPR2G_HUMAN" 5 1504.7167 59.84 79377 9378 2 1504.717999 753.3656 Small proline-rich protein 2E OS=Homo sapiens OX=9606 GN=SPRR2E PE=2 SV=2 8.06 1950.2 - 276728 - - - 0.8925 - 1.697 0.524 - 283.3 1 2 0 0.0013 13 0 0 0 1.06E+07 1.77E+05 - - - 4.2682 0.9997 221125_WJC_METTL3_EV_vs_WT_F06.09381.09381.3 2.19E-05 15/52 K.LQAAVDGPMDK[136.11]K[136.11]EE.- "sp|P51572|BAP31_HUMAN,tr|A0A2R8Y5M6|A0A2R8Y5M6_HUMAN" 2 1545.768 1.12 79378 9381 3 1545.771953 516.2633 B-cell receptor-associated protein 31 OS=Homo sapiens OX=9606 GN=BCAP31 PE=1 SV=3 4.54 1950.7 - 3.88E+06 - - - 2.5838 - 2.763 0.5 - 279 1 2 1 0.004 14 0 0 0 1.05E+08 9.39E+07 - - - 6.8143 0.9994 221125_WJC_METTL3_EV_vs_WT_F06.09384.09384.3 0.02 Oct-36 K.QQEELDALK[136.11]K[136.11].T sp|O95347|SMC2_HUMAN 1 1216.6634 0.81 79381 9384 3 1216.66258 406.5617 Structural maintenance of chromosomes protein 2 OS=Homo sapiens OX=9606 GN=SMC2 PE=1 SV=2 4.68 1950.9 - 1.60E+06 - - - -0.6879 - 1.673 0.328 - 176.2 1 2 0 -0.0008 10 0 0 0 1.22E+07 1.52E+07 - - - 3.6996 0.9948 221125_WJC_METTL3_EV_vs_WT_F06.09386.09386.2 0.0482 16-Jul R.NNFEGEVTK[136.11].E "sp|P07237|PDIA1_HUMAN,tr|A0A7P0TA97|A0A7P0TA97_HUMAN,tr|A0A7P0T8C0|A0A7P0T8C0_HUMAN,tr|H7BZ94|H7BZ94_HUMAN,tr|A0A7P0TA71|A0A7P0TA71_HUMAN,tr|I3L4M2|I3L4M2_HUMAN,tr|A0A7P0T9D6|A0A7P0T9D6_HUMAN,tr|A0A7P0T9K9|A0A7P0T9K9_HUMAN,tr|H0Y3Z3|H0Y3Z3_HUMAN,tr|A0A7P0Z4S2|A0A7P0Z4S2_HUMAN,tr|A0A7P0TA35|A0A7P0TA35_HUMAN,tr|I3L514|I3L514_HUMAN,tr|A0A7P0TB26|A0A7P0TB26_HUMAN,tr|A0A7P0T9U6|A0A7P0T9U6_HUMAN,tr|I3L0S0|I3L0S0_HUMAN,tr|I3L3P5|I3L3P5_HUMAN,tr|A0A7P0T8J3|A0A7P0T8J3_HUMAN,tr|A0A7P0Z4J0|A0A7P0Z4J0_HUMAN,tr|A0A7P0T8X1|A0A7P0T8X1_HUMAN" 19 1044.4967 3.68 79383 9386 2 1044.498414 523.2556 Protein disulfide-isomerase OS=Homo sapiens OX=9606 GN=P4HB PE=1 SV=3 4.53 1951.1 - 566540 - - - 1.6036 - 1.332 0.223 - 125.5 1 2 0 0.0017 9 0 0 0 1.72E+07 4.66E+06 - - - 1.5169 0.9965 221125_WJC_METTL3_EV_vs_WT_F06.09388.09388.2 0.000121 26-Sep K.LQAAVDGPMDK[136.11]K[136.11]EE.- "sp|P51572|BAP31_HUMAN,tr|A0A2R8Y5M6|A0A2R8Y5M6_HUMAN" 2 1545.768 1.12 79385 9388 2 1545.765752 773.8913 B-cell receptor-associated protein 31 OS=Homo sapiens OX=9606 GN=BCAP31 PE=1 SV=3 4.54 1951.4 - 320303 - - - -1.4278 - 2.092 0.421 - 177.1 1 2 1 -0.0022 14 0 0 0 5.83E+06 5.20E+06 - - - 4.0021 0.9998 221125_WJC_METTL3_EV_vs_WT_F06.09390.09390.2 0.000206 24-Oct K.ETPPNGNLSPAPR.L sp|P48634|PRC2A_HUMAN 1 1348.6735 0.08 79386 9390 2 1348.673599 675.344 Protein PRRC2A OS=Homo sapiens OX=9606 GN=PRRC2A PE=1 SV=3 6.1 1951.6 - 1.76E+06 - - - 0.0526 - 1.815 0.492 - 128.8 1 2 0 0.0001 13 0 0 0 5.17E+07 6.88E+08 - - - 4.2048 1 221125_WJC_METTL3_EV_vs_WT_F06.09394.09394.3 2.84E-05 Dec-40 K.ITKPDGIVEER.R "sp|O00165|HAX1_HUMAN,tr|Q5VYD6|Q5VYD6_HUMAN,tr|E9PIQ7|E9PIQ7_HUMAN" 3 1255.6772 1.45 79389 9394 3 1255.676163 419.5663 HCLS1-associated protein X-1 OS=Homo sapiens OX=9606 GN=HAX1 PE=1 SV=2 4.68 1951.9 - 1.08E+07 - - - -0.8386 - 2.259 0.513 - 229.3 1 2 0 -0.0011 11 0 0 0 2.01E+08 1.39E+08 - - - 6.5742 0.9999 221125_WJC_METTL3_EV_vs_WT_F06.09395.09395.2 0.04 16/24 R.STNIAAAASEPHS.- sp|Q7Z4H3|HDDC2_HUMAN 1 1254.584 - 79390 9395 2 1254.585332 628.2993 5'-deoxynucleotidase HDDC2 OS=Homo sapiens OX=9606 GN=HDDC2 PE=1 SV=1 5.22 1952 - 2.79E+06 - - - 1.0266 - 2.832 0.538 - 807.8 1 2 0 0.0013 13 0 0 0 - - - - - 5.686 0.9999 221125_WJC_METTL3_EV_vs_WT_F06.09398.09398.2 0.00746 22-Oct K.YIC[160.03]ENQDSISSK.L "sp|P02768|ALBU_HUMAN,tr|B7WNR0|B7WNR0_HUMAN,tr|H0YA55|H0YA55_HUMAN,tr|A0A0C4DGB6|A0A0C4DGB6_HUMAN,tr|D6RHD5|D6RHD5_HUMAN,tr|C9JKR2|C9JKR2_HUMAN" 6 1442.6348 32.41 79393 9398 2 1442.634902 722.3247 Albumin OS=Homo sapiens OX=9606 GN=ALB PE=1 SV=2 4.37 1952.2 - 1.84E+06 - - - 0.0991 - 2.136 0.51 - 242.5 1 2 0 0.0001 12 0 0 0 1.10E+08 3.41E+06 - - - 4.8047 0.9992 221125_WJC_METTL3_EV_vs_WT_F06.09399.09399.3 0.00649 Dec-44 R.LRPESALAQAQK.C sp|O94826|TOM70_HUMAN 1 1310.7306 0.84 79394 9399 3 1310.730228 437.9175 Mitochondrial import receptor subunit TOM70 OS=Homo sapiens OX=9606 GN=TOMM70 PE=1 SV=1 8.75 1952.2 - 1.35E+06 - - - -0.3212 - 2.037 0.263 - 214.5 1 2 0 -0.0004 12 0 0 0 3.56E+07 4.23E+07 - - - 3.4442 0.9999 221125_WJC_METTL3_EV_vs_WT_F06.09403.09403.2 4.00E-06 13/28 R.LIQSHPESAEDLQEK.C "sp|Q13813|SPTN1_HUMAN,tr|A0A0D9SF54|A0A0D9SF54_HUMAN,tr|A0A0D9SGF6|A0A0D9SGF6_HUMAN" 3 1722.8424 2.64 79398 9403 2 1722.843305 862.4285 "Spectrin alpha chain, non-erythrocytic 1 OS=Homo sapiens OX=9606 GN=SPTAN1 PE=1 SV=3" 4.4 1952.8 - 262950 - - - 0.4998 - 2.673 0.558 - 443.4 1 2 0 0.0009 15 0 0 0 2.97E+06 1.12E+06 - - - 5.5794 0.9999 221125_WJC_METTL3_EV_vs_WT_F06.09406.09406.3 2.71E-05 Dec-40 K.ITK[136.11]PDGIVEER[166.11].R "sp|O00165|HAX1_HUMAN,tr|Q5VYD6|Q5VYD6_HUMAN,tr|E9PIQ7|E9PIQ7_HUMAN" 3 1273.6997 1.48 79399 9406 3 1273.698864 425.5738 HCLS1-associated protein X-1 OS=Homo sapiens OX=9606 GN=HAX1 PE=1 SV=2 4.68 1953.2 - 8.26E+06 - - - -0.6454 - 2.332 0.379 - 212.6 1 2 0 -0.0008 11 0 0 0 2.01E+08 1.36E+08 - - - 5.1707 0.9999 221125_WJC_METTL3_EV_vs_WT_F06.09407.09407.3 0.0877 16/40 R.EMEAELEDERK.Q sp|P35579|MYH9_HUMAN 1 1377.6082 1.36 79400 9407 3 1377.609384 460.21 Myosin-9 OS=Homo sapiens OX=9606 GN=MYH9 PE=1 SV=4 4.14 1953.2 - 3.07E+06 - - - 0.8522 - 2.415 0.413 - 353.5 1 2 0 0.0012 11 0 0 0 8.43E+07 6.18E+07 - - - 5.649 0.9987 221125_WJC_METTL3_EV_vs_WT_F06.09409.09409.2 1.69E-05 22-Oct K.VGGTSDVEVNEK[136.11].K "sp|P10809|CH60_HUMAN,tr|A0A7I2V2X6|A0A7I2V2X6_HUMAN,tr|A0A7I2YQK6|A0A7I2YQK6_HUMAN,tr|A0A7I2V599|A0A7I2V599_HUMAN" 4 1240.6027 1.16 79402 9409 2 1240.599433 621.3086 "60 kDa heat shock protein, mitochondrial OS=Homo sapiens OX=9606 GN=HSPD1 PE=1 SV=2" 4.14 1953.5 - 635835 - - - -2.602 - 2.309 0.277 - 362.7 1 2 0 -0.0032 12 0 0 0 1.39E+07 1.19E+07 - - - 3.2877 0.9999 221125_WJC_METTL3_EV_vs_WT_F06.09411.09411.2 3.34E-06 20-Dec R.EMEAELEDER[166.11]K[136.11].Q sp|P35579|MYH9_HUMAN 1 1395.6307 1.08 79404 9411 2 1395.629765 698.8226 Myosin-9 OS=Homo sapiens OX=9606 GN=MYH9 PE=1 SV=4 4.14 1953.7 - 517523 - - - -0.6556 - 2.174 0.547 - 661 1 2 0 -0.0009 11 0 0 0 1.06E+07 9.81E+06 - - - 5.1817 0.9998 221125_WJC_METTL3_EV_vs_WT_F06.09416.09416.3 4.34E-05 14/44 K.EAPPMEK[136.11]PEVVK[136.11].T "sp|P62841|RS15_HUMAN,tr|K7EJ78|K7EJ78_HUMAN,tr|K7EM56|K7EM56_HUMAN,tr|A0A0B4J2B4|A0A0B4J2B4_HUMAN,tr|S4R456|S4R456_HUMAN,tr|K7ELC2|K7ELC2_HUMAN,tr|K7EQJ5|K7EQJ5_HUMAN,tr|S4R417|S4R417_HUMAN" 8 1368.7294 1.27 79407 9416 3 1368.725069 457.2504 40S ribosomal protein S15 OS=Homo sapiens OX=9606 GN=RPS15 PE=1 SV=2 4.79 1954.4 - 2.49E+06 - - - -3.1555 - 2.719 0.436 - 307.1 1 2 0 -0.0043 12 0 0 0 3.61E+08 2.84E+08 - - - 6.1724 0.9971 221125_WJC_METTL3_EV_vs_WT_F06.09420.09420.2 0.173 18-Sep R.GTHNFSEELK.L "sp|P51617|IRAK1_HUMAN,tr|F8WAB6|F8WAB6_HUMAN,tr|D3YTB5|D3YTB5_HUMAN" 3 1160.5462 1.76 79411 9420 2 1160.543654 581.2804 Interleukin-1 receptor-associated kinase 1 OS=Homo sapiens OX=9606 GN=IRAK1 PE=1 SV=2 5.4 1954.9 - 652876 - - - -2.1955 - 1.259 0.345 - 148.3 1 2 0 -0.0025 10 0 0 0 8.71E+06 4.95E+06 - - - 2.2313 0.9988 221125_WJC_METTL3_EV_vs_WT_F06.09421.09421.2 0.087 18-Aug R.GTHNFSEELK[136.11].L "sp|P51617|IRAK1_HUMAN,tr|F8WAB6|F8WAB6_HUMAN,tr|D3YTB5|D3YTB5_HUMAN" 3 1168.5604 1.76 79412 9421 2 1168.557737 585.2875 Interleukin-1 receptor-associated kinase 1 OS=Homo sapiens OX=9606 GN=IRAK1 PE=1 SV=2 5.4 1955 - 520779 - - - -2.2806 - 1.862 0.318 - 183.7 1 2 0 -0.0027 10 0 0 0 8.71E+06 4.95E+06 - - - 3.1241 0.9837 221125_WJC_METTL3_EV_vs_WT_F06.09423.09423.2 0.000689 26-Jul K.LQAAVDGPMDK[136.11]K[136.11]EE.- "sp|P51572|BAP31_HUMAN,tr|A0A2R8Y5M6|A0A2R8Y5M6_HUMAN" 2 1545.768 1.12 79414 9423 2 1545.763641 773.8913 B-cell receptor-associated protein 31 OS=Homo sapiens OX=9606 GN=BCAP31 PE=1 SV=3 4.54 1955.3 - 393804 - - - -2.7934 - 1.996 0.342 - 127 1 2 1 -0.0043 14 0 0 0 5.83E+06 5.20E+06 - - - 3.3001 0.999 221125_WJC_METTL3_EV_vs_WT_F06.09427.09427.2 7.93E-07 14/22 K.LPQTSDDEK[136.11]K[136.11]DF.- sp|Q9GZT3|SLIRP_HUMAN 1 1437.6958 0.96 79415 9427 2 1437.694624 719.8552 "SRA stem-loop-interacting RNA-binding protein, mitochondrial OS=Homo sapiens OX=9606 GN=SLIRP PE=1 SV=1" 4.23 1955.7 - 3.91E+06 - - - -0.8451 - 2.378 0.593 - 572.4 1 2 1 -0.0012 12 0 0 0 1.64E+08 1.71E+08 - - - 5.6998 0.9983 221125_WJC_METTL3_EV_vs_WT_F06.09428.09428.3 0.115 Nov-36 K.TSLK[136.11]PAHLLR[166.11].H sp|Q8N0Y2|ZN444_HUMAN 1 1152.7098 0.01 79416 9428 3 1152.708412 385.2439 Zinc finger protein 444 OS=Homo sapiens OX=9606 GN=ZNF444 PE=1 SV=1 11 1955.7 - 2.32E+06 - - - -1.2015 - 2.056 0.212 - 167 1 2 0 -0.0014 10 0 0 0 3.39E+05 4.02E+07 - - - 3.0081 0.9998 221125_WJC_METTL3_EV_vs_WT_F06.09430.09430.2 0.000642 13/22 R.LRPESALAQAQK.C sp|O94826|TOM70_HUMAN 1 1310.7306 1.89 79418 9430 2 1310.728709 656.3726 Mitochondrial import receptor subunit TOM70 OS=Homo sapiens OX=9606 GN=TOMM70 PE=1 SV=1 8.75 1956 - 1.28E+06 - - - -1.4801 - 2.648 0.437 - 409.9 1 2 0 -0.0019 12 0 0 0 1.70E+07 9.01E+06 - - - 4.8303 1 221125_WJC_METTL3_EV_vs_WT_F06.09431.09431.2 4.64E-07 22-Nov R.NPATTNQTEFER[166.11].V sp|P50750|CDK9_HUMAN 1 1416.6509 0.001 79419 9431 2 1416.653077 709.3327 Cyclin-dependent kinase 9 OS=Homo sapiens OX=9606 GN=CDK9 PE=1 SV=3 4.53 1956.1 - 1.18E+06 - - - 1.5424 - 2.535 0.597 - 533.2 1 2 0 0.0022 12 0 0 0 0.00E+00 1.30E+07 - - - 5.8973 1 221125_WJC_METTL3_EV_vs_WT_F06.09432.09432.2 1.61E-07 14/24 R.NC[160.03]TIVSPDAGGAK.R "sp|P60891|PRPS1_HUMAN,tr|A0A2R8Y7H4|A0A2R8Y7H4_HUMAN,tr|A0A6Q8PGX9|A0A6Q8PGX9_HUMAN,tr|B1ALA9|B1ALA9_HUMAN,tr|A0A6Q8PGP2|A0A6Q8PGP2_HUMAN,tr|A0A6Q8PHI4|A0A6Q8PHI4_HUMAN,tr|A0A6Q8PG13|A0A6Q8PG13_HUMAN" 7 1288.6082 0.58 79420 9432 2 1288.606798 645.3114 Ribose-phosphate pyrophosphokinase 1 OS=Homo sapiens OX=9606 GN=PRPS1 PE=1 SV=2 5.83 1956.2 - 1.15E+06 - - - -1.05 - 2.521 0.623 - 866.8 1 2 0 -0.0014 13 0 0 0 3.08E+07 5.34E+07 - - - 6.0152 0.9999 221125_WJC_METTL3_EV_vs_WT_F06.09435.09435.2 0.000173 14/20 R.EMEAELEDERK.Q sp|P35579|MYH9_HUMAN 1 1377.6082 1.08 79423 9435 2 1377.608828 689.8114 Myosin-9 OS=Homo sapiens OX=9606 GN=MYH9 PE=1 SV=4 4.14 1956.6 - 850674 - - - 0.4486 - 2.38 0.52 - 520.5 1 2 0 0.0006 11 0 0 0 1.06E+07 9.81E+06 - - - 5.2272 0.8753 221125_WJC_METTL3_EV_vs_WT_F06.09437.09437.2 0.0513 18-Jun L.EESNYELEGK.L "sp|P13645|K1C10_HUMAN,tr|A0A1B0GVI3|A0A1B0GVI3_HUMAN" 2 1196.5197 0.48 79425 9437 2 1196.518986 599.2671 "Keratin, type I cytoskeletal 10 OS=Homo sapiens OX=9606 GN=KRT10 PE=1 SV=6" 4.09 1956.9 - 487642 - - - -0.6076 - 1.299 0.261 - 103.7 1 1 0 -0.0007 10 0 0 0 3.26E+06 6.72E+06 - - - 1.6987 0.99 221125_WJC_METTL3_EV_vs_WT_F06.09440.09440.2 0.000482 13/20 V.ASNSELVQSSR.S "sp|P08779|K1C16_HUMAN,tr|K7ENW6|K7ENW6_HUMAN" 2 1176.5735 3.2 79428 9440 2 1176.575255 589.294 "Keratin, type I cytoskeletal 16 OS=Homo sapiens OX=9606 GN=KRT16 PE=1 SV=4" 6.05 1957.3 - 453016 - - - 1.5095 - 2.823 0.466 - 901 1 1 0 0.0018 11 0 0 0 3.12E+06 9.77E+05 - - - 5.2898 0.9953 221125_WJC_METTL3_EV_vs_WT_F06.09444.09444.3 0.166 Sep-44 R.LR[166.11]PESALAQAQK[136.11].C sp|O94826|TOM70_HUMAN 1 1328.7531 1.28 79430 9444 3 1328.751911 443.925 Mitochondrial import receptor subunit TOM70 OS=Homo sapiens OX=9606 GN=TOMM70 PE=1 SV=1 8.75 1957.7 - 2.03E+06 - - - -0.9091 - 1.966 0.179 - 157 2 2 0 -0.0012 12 0 0 0 3.52E+07 2.76E+07 - - - 2.2698 1 221125_WJC_METTL3_EV_vs_WT_F06.09448.09448.2 5.86E-08 17/28 R.LQGQLEQGDDTAAER[166.11].L "sp|Q8NE71|ABCF1_HUMAN,tr|Q5STZ8|Q5STZ8_HUMAN,tr|H0YGW7|H0YGW7_HUMAN" 3 1639.7677 0.96 79434 9448 2 1639.770548 820.8911 ATP-binding cassette sub-family F member 1 OS=Homo sapiens OX=9606 GN=ABCF1 PE=1 SV=2 3.92 1958.1 - 683884 - - - 1.7295 - 3.283 0.586 - 1255.1 1 2 0 0.0028 15 0 0 0 3.71E+07 3.88E+07 - - - 6.2909 0.994 221125_WJC_METTL3_EV_vs_WT_F06.09450.09450.2 0.0176 26-Nov K.LQAAVDGPMDKKEE.- "sp|P51572|BAP31_HUMAN,tr|A0A2R8Y5M6|A0A2R8Y5M6_HUMAN" 2 1529.7396 1.12 79436 9450 2 1529.737134 765.8771 B-cell receptor-associated protein 31 OS=Homo sapiens OX=9606 GN=BCAP31 PE=1 SV=3 4.54 1958.4 - 397394 - - - -1.5852 - 2.15 0.339 - 158.9 1 2 1 -0.0024 14 0 0 0 5.83E+06 5.20E+06 - - - 3.465 0.9988 221125_WJC_METTL3_EV_vs_WT_F06.09452.09452.2 0.0152 16-Aug K.ESEFDDEPK[136.11].F "sp|Q9Y2W1|TR150_HUMAN,tr|A0A3B3ITZ9|A0A3B3ITZ9_HUMAN" 2 1102.4546 3.14 79437 9452 2 1102.455137 552.2346 Thyroid hormone receptor-associated protein 3 OS=Homo sapiens OX=9606 GN=THRAP3 PE=1 SV=2 3.83 1958.6 - 419423 - - - 0.4871 - 1.356 0.315 - 240.4 1 2 0 0.0005 9 0 0 0 3.75E+08 1.19E+08 - - - 2.2485 0.9999 221125_WJC_METTL3_EV_vs_WT_F06.09455.09455.2 0.0097 18-Oct K.AEAESLYQSK.Y sp|P04264|K2C1_HUMAN 1 1124.535 999 79439 9455 2 1124.534047 563.2748 "Keratin, type II cytoskeletal 1 OS=Homo sapiens OX=9606 GN=KRT1 PE=1 SV=6" 4.53 1958.8 - 3.79E+06 - - - -0.8199 - 2.23 0.516 - 396.6 1 2 0 -0.0009 10 0 0 0 8.12E+07 0.00E+00 - - - 5.0905 0.9862 221125_WJC_METTL3_EV_vs_WT_F06.09457.09457.2 7.86E-05 20-Sep K.R[166.11]GLLQDDAHPT.L "sp|Q86U44|MTA70_HUMAN,tr|F5H6D8|F5H6D8_HUMAN,tr|H0YFV6|H0YFV6_HUMAN,tr|B4DTN4|B4DTN4_HUMAN" 4 1231.6185 0.47 79441 9457 2 1231.619204 616.8165 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 5.21 1959 - 1.61E+06 - - - 0.5968 - 1.719 0.478 - 234.7 1 1 0 0.0007 11 0 0 0 2.24E+07 4.77E+07 - - - 4.0368 0.9999 221125_WJC_METTL3_EV_vs_WT_F06.09458.09458.2 6.69E-05 13/24 K.GPGEVAGTVTGQK[136.11].R "sp|Q86U44|MTA70_HUMAN,tr|F5H6D8|F5H6D8_HUMAN,tr|H0YFV6|H0YFV6_HUMAN,tr|B4DTN4|B4DTN4_HUMAN" 4 1207.6288 0.03 79442 9458 2 1207.629607 604.8217 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 6 1959.1 - 1.32E+06 - - - 0.655 - 2.689 0.56 - 803.7 1 2 0 0.0008 13 0 0 0 6.22E+08 2.37E+10 - - - 5.7156 1 221125_WJC_METTL3_EV_vs_WT_F06.09459.09459.2 8.72E-12 16/28 R.LQGQLEQGDDTAAER.L "sp|Q8NE71|ABCF1_HUMAN,tr|Q5STZ8|Q5STZ8_HUMAN,tr|H0YGW7|H0YGW7_HUMAN" 3 1629.7594 0.96 79443 9459 2 1629.759988 815.887 ATP-binding cassette sub-family F member 1 OS=Homo sapiens OX=9606 GN=ABCF1 PE=1 SV=2 3.92 1959.2 - 916243 - - - 0.335 - 3.304 0.679 - 1130.1 1 2 0 0.0005 15 0 0 0 3.71E+07 3.88E+07 - - - 6.9942 1 221125_WJC_METTL3_EV_vs_WT_F06.09460.09460.3 2.44E-07 15/56 K.VLQPHPVTPSDTETR.W "sp|P57678|GEMI4_HUMAN,tr|I3L4M4|I3L4M4_HUMAN,tr|E7EN12|E7EN12_HUMAN,tr|I3L4A4|I3L4A4_HUMAN,tr|I3L2C7|I3L2C7_HUMAN,tr|I3L399|I3L399_HUMAN" 6 1675.8529 1.13 79444 9460 3 1675.851836 559.6249 Gem-associated protein 4 OS=Homo sapiens OX=9606 GN=GEMIN4 PE=1 SV=2 5.32 1959.4 - 799423 - - - -0.6641 - 3.038 0.539 - 344.1 1 2 0 -0.0011 15 0 0 0 7.59E+06 6.70E+06 - - - 7.4485 0.9999 221125_WJC_METTL3_EV_vs_WT_F06.09464.09464.3 0.00304 Dec-44 K.LPQTSDDEKKDF.- sp|Q9GZT3|SLIRP_HUMAN 1 1421.6674 1.39 79447 9464 3 1421.667422 474.8964 "SRA stem-loop-interacting RNA-binding protein, mitochondrial OS=Homo sapiens OX=9606 GN=SLIRP PE=1 SV=1" 4.23 1959.8 - 2.16E+07 - - - -0.012 - 2.213 0.512 - 147.6 1 2 1 0 12 0 0 0 1.53E+09 1.10E+09 - - - 6.4501 0.9987 221125_WJC_METTL3_EV_vs_WT_F06.09466.09466.3 0.000126 Dec-48 R.EVATNSELVQSGK.S "sp|Q04695|K1C17_HUMAN,sp|P02533|K1C14_HUMAN,tr|K7ESE1|K7ESE1_HUMAN,tr|F5GWP8|F5GWP8_HUMAN" 4 1360.6834 4.03 79448 9466 3 1360.681683 454.5684 "Keratin, type I cytoskeletal 17 OS=Homo sapiens OX=9606 GN=KRT17 PE=1 SV=2" 4.53 1960 - 3.33E+06 - - - -1.2795 - 2.042 0.244 - 242.7 1 2 0 -0.0017 13 0 0 0 5.72E+07 1.42E+07 - - - 3.1955 0.9994 221125_WJC_METTL3_EV_vs_WT_F06.09478.09478.2 0.000133 22-Aug K.EAPPMEKPEVVK.T "sp|P62841|RS15_HUMAN,tr|K7EJ78|K7EJ78_HUMAN,tr|K7EM56|K7EM56_HUMAN,tr|A0A0B4J2B4|A0A0B4J2B4_HUMAN,tr|S4R456|S4R456_HUMAN,tr|K7ELC2|K7ELC2_HUMAN,tr|K7EQJ5|K7EQJ5_HUMAN,tr|S4R417|S4R417_HUMAN" 8 1352.701 1.74 79460 9478 2 1352.702713 677.3578 40S ribosomal protein S15 OS=Homo sapiens OX=9606 GN=RPS15 PE=1 SV=2 4.79 1961.3 - 491333 - - - 1.2752 - 1.745 0.378 - 125 1 2 0 0.0017 12 0 0 0 2.81E+07 1.62E+07 - - - 3.2973 0.9524 221125_WJC_METTL3_EV_vs_WT_F06.09479.09479.2 0.000374 22-Nov F.STISTAVQSTGK.S "sp|Q9NRY5|F1142_HUMAN,tr|E7ESJ7|E7ESJ7_HUMAN,tr|E5RGF9|E5RGF9_HUMAN" 3 1178.6143 1.31 79461 9479 2 1178.618129 590.3144 Protein FAM114A2 OS=Homo sapiens OX=9606 GN=FAM114A2 PE=1 SV=4 8.47 1961.4 - 339510 - - - 3.264 - 2.267 0.448 - 278.5 1 1 0 0.0038 12 0 0 0 2.93E+07 2.24E+07 - - - 4.5022 0.9971 221125_WJC_METTL3_EV_vs_WT_F06.09481.09481.2 0.000695 20-Nov R.KDDPTLLSSGR.V "sp|P22061|PIMT_HUMAN,tr|F6S8N6|F6S8N6_HUMAN,tr|A0A3F2YNX8|A0A3F2YNX8_HUMAN,tr|A0A0A0MRJ6|A0A0A0MRJ6_HUMAN" 4 1187.6146 1.26 79463 9481 2 1187.618512 594.8146 Protein-L-isoaspartate(D-aspartate) O-methyltransferase OS=Homo sapiens OX=9606 GN=PCMT1 PE=1 SV=4 5.96 1961.7 - 310693 - - - 3.2805 - 1.999 0.283 - 286.2 1 2 0 0.0039 11 0 0 0 5.22E+06 4.15E+06 - - - 3.0038 0.9867 221125_WJC_METTL3_EV_vs_WT_F06.09482.09482.2 0.000138 18-Dec A.PPMEK[136.11]PEVVK[136.11].T "sp|P62841|RS15_HUMAN,tr|K7EJ78|K7EJ78_HUMAN,tr|K7EM56|K7EM56_HUMAN,tr|A0A0B4J2B4|A0A0B4J2B4_HUMAN,tr|S4R456|S4R456_HUMAN,tr|K7ELC2|K7ELC2_HUMAN,tr|K7EQJ5|K7EQJ5_HUMAN,tr|S4R417|S4R417_HUMAN" 8 1168.6497 3.02 79464 9482 2 1168.647938 585.3321 40S ribosomal protein S15 OS=Homo sapiens OX=9606 GN=RPS15 PE=1 SV=2 6.56 1961.8 - 268392 - - - -1.4915 - 2.485 0.401 - 585.8 1 1 0 -0.0017 10 0 0 0 1.87E+07 6.19E+06 - - - 4.5431 0.9887 221125_WJC_METTL3_EV_vs_WT_F06.09483.09483.2 1.48 20-Jun K.SSNGTFINSQR[166.11].L "sp|Q14BN4|SLMAP_HUMAN,tr|A0A590UJK3|A0A590UJK3_HUMAN,tr|A0A590UJG7|A0A590UJG7_HUMAN,tr|A0A590UJT5|A0A590UJT5_HUMAN,tr|A0A5F9VB99|A0A5F9VB99_HUMAN,tr|A0A590UJ16|A0A590UJ16_HUMAN,tr|A0A590UJU9|A0A590UJU9_HUMAN" 7 1219.5821 3.89 79465 9483 2 1219.581783 610.7983 Sarcolemmal membrane-associated protein OS=Homo sapiens OX=9606 GN=SLMAP PE=1 SV=1 9.47 1961.9 - 237423 - - - -0.2468 - 1.023 0.194 - 87 1 2 0 -0.0003 11 0 0 0 4.37E+06 1.12E+06 - - - 0.5353 0.9999 221125_WJC_METTL3_EV_vs_WT_F06.09488.09488.3 0.000282 Nov-56 K.IITGKPSGAISGVQK.A "sp|Q9UHD2|TBK1_HUMAN,tr|A0A7I2V646|A0A7I2V646_HUMAN,tr|A0A7I2V4Z2|A0A7I2V4Z2_HUMAN,tr|A0A494C079|A0A494C079_HUMAN,tr|A0A494C045|A0A494C045_HUMAN,tr|A0A494C1M6|A0A494C1M6_HUMAN,tr|A0A494C0A8|A0A494C0A8_HUMAN,tr|A0A7I2V4W4|A0A7I2V4W4_HUMAN,tr|A0A7I2V463|A0A7I2V463_HUMAN,tr|A0A494C148|A0A494C148_HUMAN,tr|A0A494C0X2|A0A494C0X2_HUMAN,tr|A0A494C167|A0A494C167_HUMAN,tr|A0A7I2YQG1|A0A7I2YQG1_HUMAN,tr|A0A7I2V2F4|A0A7I2V2F4_HUMAN,tr|A0A494C0R4|A0A494C0R4_HUMAN,tr|A0A7I2V643|A0A7I2V643_HUMAN" 16 1454.8457 1.59 79468 9488 3 1454.846197 485.9558 Serine\threonine-protein kinase TBK1 OS=Homo sapiens OX=9606 GN=TBK1 PE=1 SV=1 10 1962.5 - 4.10E+06 - - - 0.3561 - 2.059 0.485 - 80 1 2 0 0.0005 15 0 0 0 3.41E+07 2.15E+07 - - - 5.8317 0.9978 221125_WJC_METTL3_EV_vs_WT_F06.09492.09492.3 3.55E-05 15/40 K.YFHPPAHLQAK.L "sp|Q9NR56|MBNL1_HUMAN,sp|Q5VZF2|MBNL2_HUMAN,tr|H7C4T5|H7C4T5_HUMAN,tr|Q86VM6|Q86VM6_HUMAN,tr|H7C4Y1|H7C4Y1_HUMAN,tr|A0A0A0MQX8|A0A0A0MQX8_HUMAN,tr|A0A7P0T9I3|A0A7P0T9I3_HUMAN,tr|C9JCX1|C9JCX1_HUMAN,tr|C9JP00|C9JP00_HUMAN,tr|O95205|O95205_HUMAN" 10 1307.6775 1.07 79472 9492 3 1307.677513 436.8998 Muscleblind-like protein 1 OS=Homo sapiens OX=9606 GN=MBNL1 PE=1 SV=2 8.61 1962.7 - 1.68E+06 - - - 0.0168 - 2.292 0.168 - 292.9 1 2 0 0 11 0 0 0 2.66E+07 2.48E+07 - - - 2.7693 0.9924 221125_WJC_METTL3_EV_vs_WT_F06.09493.09493.3 0.0026 Aug-40 R.K[136.11]DDPTLLSSGR[166.11].V "sp|P22061|PIMT_HUMAN,tr|F6S8N6|F6S8N6_HUMAN,tr|A0A3F2YNX8|A0A3F2YNX8_HUMAN,tr|A0A0A0MRJ6|A0A0A0MRJ6_HUMAN" 4 1205.6371 4 79473 9493 3 1205.635119 402.8863 Protein-L-isoaspartate(D-aspartate) O-methyltransferase OS=Homo sapiens OX=9606 GN=PCMT1 PE=1 SV=4 5.96 1962.8 - 1.42E+06 - - - -1.6315 - 1.88 0.166 - 64.4 1 2 0 -0.002 11 0 0 0 4.69E+07 1.17E+07 - - - 2.1835 0.9831 221125_WJC_METTL3_EV_vs_WT_F06.09494.09494.3 0.00322 Nov-40 K.YFHPPAHLQAK[136.11].L "sp|Q9NR56|MBNL1_HUMAN,sp|Q5VZF2|MBNL2_HUMAN,tr|H7C4T5|H7C4T5_HUMAN,tr|Q86VM6|Q86VM6_HUMAN,tr|H7C4Y1|H7C4Y1_HUMAN,tr|A0A0A0MQX8|A0A0A0MQX8_HUMAN,tr|A0A7P0T9I3|A0A7P0T9I3_HUMAN,tr|C9JCX1|C9JCX1_HUMAN,tr|C9JP00|C9JP00_HUMAN,tr|O95205|O95205_HUMAN" 10 1315.6917 1.52 79474 9494 3 1315.690557 439.5712 Muscleblind-like protein 1 OS=Homo sapiens OX=9606 GN=MBNL1 PE=1 SV=2 8.61 1962.8 - 1.31E+06 - - - -0.8619 - 2.057 0.081 - 146.1 1 2 0 -0.0011 11 0 0 0 2.44E+07 1.61E+07 - - - 1.4917 0.9946 221125_WJC_METTL3_EV_vs_WT_F06.09496.09496.3 0.00763 Nov-40 R.KDDPTLLSSGR.V "sp|P22061|PIMT_HUMAN,tr|F6S8N6|F6S8N6_HUMAN,tr|A0A3F2YNX8|A0A3F2YNX8_HUMAN,tr|A0A0A0MRJ6|A0A0A0MRJ6_HUMAN" 4 1187.6146 11.18 79476 9496 3 1187.614738 396.8788 Protein-L-isoaspartate(D-aspartate) O-methyltransferase OS=Homo sapiens OX=9606 GN=PCMT1 PE=1 SV=4 5.96 1963.1 - 998184 - - - 0.1027 - 1.839 0.172 - 126 1 2 0 0.0001 11 0 0 0 1.64E+08 1.47E+07 - - - 2.1883 0.9996 221125_WJC_METTL3_EV_vs_WT_F06.09500.09500.2 0.00326 20-Oct K.HAQANGFSVVR[166.11].S "sp|P53582|MAP11_HUMAN,tr|H0Y955|H0Y955_HUMAN" 2 1194.6133 0.41 79480 9500 2 1194.613901 598.3139 Methionine aminopeptidase 1 OS=Homo sapiens OX=9606 GN=METAP1 PE=1 SV=2 9.76 1963.5 - 320443 - - - 0.483 - 1.852 0.373 - 270.1 1 2 0 0.0006 11 0 0 0 4.32E+06 1.04E+07 - - - 3.4629 0.9934 221125_WJC_METTL3_EV_vs_WT_F06.09504.09504.2 0.0449 18-Nov R.KEEMDKLLDK.L sp|Q96SB3|NEB2_HUMAN 1 1247.6431 7.57 79483 9504 2 1247.643898 624.8288 Neurabin-2 OS=Homo sapiens OX=9606 GN=PPP1R9B PE=1 SV=3 4.78 1964 - 9.33E+06 - - - 0.6083 - 2.136 0.245 - 442.8 1 2 1 0.0008 10 0 0 0 1.07E+08 1.41E+07 - - - 2.9687 1 221125_WJC_METTL3_EV_vs_WT_F06.09506.09506.2 9.54E-09 16/26 R.GNLGAGNGNLQGPR.H "sp|P43243|MATR3_HUMAN,tr|D6RE02|D6RE02_HUMAN,tr|B3KM87|B3KM87_HUMAN,tr|A8MXP9|A8MXP9_HUMAN,tr|D6RAY2|D6RAY2_HUMAN,tr|D6R991|D6R991_HUMAN,tr|A0A0R4J2E8|A0A0R4J2E8_HUMAN,tr|D6RAM9|D6RAM9_HUMAN,tr|D6RIA2|D6RIA2_HUMAN,tr|H0Y8T4|H0Y8T4_HUMAN,tr|D6REM6|D6REM6_HUMAN,tr|D6RBI2|D6RBI2_HUMAN" 12 1323.6644 1.38 79484 9506 2 1323.665347 662.8395 Matrin-3 OS=Homo sapiens OX=9606 GN=MATR3 PE=1 SV=2 9.75 1964.2 - 5.68E+06 - - - 0.7457 - 2.971 0.667 - 918.2 1 2 0 0.001 14 0 0 0 1.02E+10 7.36E+09 - - - 6.6997 0.9892 221125_WJC_METTL3_EV_vs_WT_F06.09509.09509.3 0.00983 Aug-40 K.VHSVAWSC[160.03]DGR.R "sp|Q96J01|THOC3_HUMAN,tr|D6RGZ2|D6RGZ2_HUMAN" 2 1272.567 0.75 79487 9509 3 1272.560693 425.1963 THO complex subunit 3 OS=Homo sapiens OX=9606 GN=THOC3 PE=1 SV=1 6.71 1964.5 - 749507 - - - -4.92 - 1.586 0.332 - 88 1 2 0 -0.0063 11 0 0 0 9.36E+06 1.24E+07 - - - 3.55 0.9616 221125_WJC_METTL3_EV_vs_WT_F06.09510.09510.2 7.86E-05 18-Oct A.SDNQPTVTIK[136.11].V "sp|P11021|BIP_HUMAN,tr|A0A7P0TB36|A0A7P0TB36_HUMAN,tr|A0A7P0TAI0|A0A7P0TAI0_HUMAN" 3 1109.5808 0.63 79488 9510 2 1109.57806 555.7977 Endoplasmic reticulum chaperone BiP OS=Homo sapiens OX=9606 GN=HSPA5 PE=1 SV=2 5.55 1964.6 - 720729 - - - -2.4721 - 1.739 0.457 - 349.7 1 1 0 -0.0027 10 0 0 0 1.44E+07 2.30E+07 - - - 3.96 0.9693 221125_WJC_METTL3_EV_vs_WT_F06.09511.09511.2 9.86E-05 18-Dec A.PPMEKPEVVK.T "sp|P62841|RS15_HUMAN,tr|K7EJ78|K7EJ78_HUMAN,tr|K7EM56|K7EM56_HUMAN,tr|A0A0B4J2B4|A0A0B4J2B4_HUMAN,tr|S4R456|S4R456_HUMAN,tr|K7ELC2|K7ELC2_HUMAN,tr|K7EQJ5|K7EQJ5_HUMAN,tr|S4R417|S4R417_HUMAN" 8 1152.6213 1.61 79489 9511 2 1152.619841 577.3179 40S ribosomal protein S15 OS=Homo sapiens OX=9606 GN=RPS15 PE=1 SV=2 6.56 1964.7 - 691564 - - - -1.2493 - 2.408 0.242 - 429.6 1 1 0 -0.0014 10 0 0 0 7.54E+06 4.68E+06 - - - 3.2809 0.9999 221125_WJC_METTL3_EV_vs_WT_F06.09513.09513.2 0.00026 14/20 K.HFVALSTNTTK[136.11].V "sp|P06744|G6PI_HUMAN,tr|A0A2R8Y6C7|A0A2R8Y6C7_HUMAN,tr|A0A0J9YYH3|A0A0J9YYH3_HUMAN,tr|K7EQ48|K7EQ48_HUMAN,tr|A0A2U3TZU2|A0A2U3TZU2_HUMAN,tr|A0A0J9YXP8|A0A0J9YXP8_HUMAN,tr|A0A0J9YX90|A0A0J9YX90_HUMAN" 7 1225.6546 0.84 79491 9513 2 1225.654871 613.8346 Glucose-6-phosphate isomerase OS=Homo sapiens OX=9606 GN=GPI PE=1 SV=4 8.76 1965 - 336041 - - - 0.1909 - 2.533 0.539 - 555.4 1 2 0 0.0002 11 0 0 0 1.12E+07 1.33E+07 - - - 5.5362 0.9997 221125_WJC_METTL3_EV_vs_WT_F06.09514.09514.2 2.74E-07 13/20 K.HFVALSTNTTK.V "sp|P06744|G6PI_HUMAN,tr|A0A2R8Y6C7|A0A2R8Y6C7_HUMAN,tr|A0A0J9YYH3|A0A0J9YYH3_HUMAN,tr|K7EQ48|K7EQ48_HUMAN,tr|A0A2U3TZU2|A0A2U3TZU2_HUMAN,tr|A0A0J9YXP8|A0A0J9YXP8_HUMAN,tr|A0A0J9YX90|A0A0J9YX90_HUMAN" 7 1217.6404 0.86 79492 9514 2 1217.637321 609.8275 Glucose-6-phosphate isomerase OS=Homo sapiens OX=9606 GN=GPI PE=1 SV=4 8.76 1965.1 - 278414 - - - -2.559 - 2.803 0.503 - 458.5 1 2 0 -0.0031 11 0 0 0 1.15E+07 1.33E+07 - - - 5.5434 0.9403 221125_WJC_METTL3_EV_vs_WT_F06.09516.09516.2 1.76 18-Aug R.K[136.11]EEMDKLLDK[136.11].L sp|Q96SB3|NEB2_HUMAN 1 1263.6715 - 79493 9516 2 1263.671912 632.843 Neurabin-2 OS=Homo sapiens OX=9606 GN=PPP1R9B PE=1 SV=3 4.78 1965.3 - 5.92E+06 - - - 0.2952 - 1.666 0.078 - 241.5 1 2 1 0.0004 10 0 0 0 - - - - - 1.0417 0.9999 221125_WJC_METTL3_EV_vs_WT_F06.09518.09518.3 0.000288 Oct-44 K.ISNDNPEEHVLK[136.11].V "sp|Q9H2P0|ADNP_HUMAN,tr|A0A2R8Y6X0|A0A2R8Y6X0_HUMAN,tr|A0A669KBJ7|A0A669KBJ7_HUMAN" 3 1401.698 1.02 79495 9518 3 1401.69831 468.2399 Activity-dependent neuroprotector homeobox protein OS=Homo sapiens OX=9606 GN=ADNP PE=1 SV=1 4.65 1965.4 - 2.28E+06 - - - 0.2511 - 2.176 0.401 - 149.1 1 2 0 0.0004 12 0 0 0 5.86E+07 5.73E+07 - - - 5.1657 0.9999 221125_WJC_METTL3_EV_vs_WT_F06.09519.09519.3 2.23E-05 Dec-44 K.ISNDNPEEHVLK.V "sp|Q9H2P0|ADNP_HUMAN,tr|A0A2R8Y6X0|A0A2R8Y6X0_HUMAN,tr|A0A669KBJ7|A0A669KBJ7_HUMAN" 3 1393.6838 1.05 79496 9519 3 1393.683573 465.5685 Activity-dependent neuroprotector homeobox protein OS=Homo sapiens OX=9606 GN=ADNP PE=1 SV=1 4.65 1965.5 - 2.28E+06 - - - -0.1327 - 2.339 0.432 - 239.8 1 2 0 -0.0002 12 0 0 0 6.00E+07 5.73E+07 - - - 5.7116 0.9997 221125_WJC_METTL3_EV_vs_WT_F06.09523.09523.3 6.35E-05 17/44 R.LREC[160.03]ELSPGVNR.D "sp|Q9BXP5|SRRT_HUMAN,tr|H7C3A1|H7C3A1_HUMAN" 2 1428.7143 1.07 79500 9523 3 1428.712932 477.2454 Serrate RNA effector molecule homolog OS=Homo sapiens OX=9606 GN=SRRT PE=1 SV=1 6.14 1965.8 - 1.01E+06 - - - -0.9904 - 2.437 0.414 - 515.4 1 2 1 -0.0014 12 0 0 0 5.06E+07 4.75E+07 - - - 5.6244 0.9997 221125_WJC_METTL3_EV_vs_WT_F06.09526.09526.2 8.56E-06 22-Oct K.EAPPMEK[136.11]PEVVK[136.11].T "sp|P62841|RS15_HUMAN,tr|K7EJ78|K7EJ78_HUMAN,tr|K7EM56|K7EM56_HUMAN,tr|A0A0B4J2B4|A0A0B4J2B4_HUMAN,tr|S4R456|S4R456_HUMAN,tr|K7ELC2|K7ELC2_HUMAN,tr|K7EQJ5|K7EQJ5_HUMAN,tr|S4R417|S4R417_HUMAN" 8 1368.7294 1.74 79503 9526 2 1368.73206 685.372 40S ribosomal protein S15 OS=Homo sapiens OX=9606 GN=RPS15 PE=1 SV=2 4.79 1966.2 - 561345 - - - 1.9522 - 2.036 0.48 - 223.6 1 2 0 0.0027 12 0 0 0 2.83E+07 1.63E+07 - - - 4.4562 0.785 221125_WJC_METTL3_EV_vs_WT_F06.09531.09531.3 0.332 Jul-40 K.QHTFVETESVR[166.11].Y "sp|P48444|COPD_HUMAN,tr|B0YIW6|B0YIW6_HUMAN,tr|Q6P1Q5|Q6P1Q5_HUMAN" 3 1341.6552 1.75 79505 9531 3 1341.653415 448.2257 Coatomer subunit delta OS=Homo sapiens OX=9606 GN=ARCN1 PE=1 SV=1 5.4 1966.8 - 1.80E+06 - - - -1.367 - 1.437 0.044 - 113.1 1 2 0 -0.0018 11 0 0 0 7.81E+07 4.48E+07 - - - 0.06 0.9992 221125_WJC_METTL3_EV_vs_WT_F06.09533.09533.2 0.0149 16-Oct R.EQEVNILKK.T sp|P35579|MYH9_HUMAN 1 1099.6237 1.16 79507 9533 2 1099.624444 550.8191 Myosin-9 OS=Homo sapiens OX=9606 GN=MYH9 PE=1 SV=4 6.24 1967 - 1.58E+06 - - - 0.6548 - 1.847 0.253 - 463 1 2 0 0.0007 9 0 0 0 2.43E+07 2.10E+07 - - - 2.6845 0.9993 221125_WJC_METTL3_EV_vs_WT_F06.09534.09534.2 0.00109 16-Sep R.EQEVNILK[136.11]K[136.11].T sp|P35579|MYH9_HUMAN 1 1115.6521 1.15 79508 9534 2 1115.651997 558.8333 Myosin-9 OS=Homo sapiens OX=9606 GN=MYH9 PE=1 SV=4 6.24 1967.1 - 1.50E+06 - - - -0.1138 - 1.641 0.3 - 344.6 1 2 0 -0.0001 9 0 0 0 2.41E+07 2.10E+07 - - - 2.6897 0.9996 221125_WJC_METTL3_EV_vs_WT_F06.09536.09536.3 0.00773 Nov-40 K.GEIDAHEDSFK[136.11].S "sp|Q13813|SPTN1_HUMAN,tr|A0A0D9SF54|A0A0D9SF54_HUMAN,tr|A0A0D9SGF6|A0A0D9SGF6_HUMAN" 3 1254.5608 1.79 79510 9536 3 1254.556697 419.1942 "Spectrin alpha chain, non-erythrocytic 1 OS=Homo sapiens OX=9606 GN=SPTAN1 PE=1 SV=3" 4.31 1967.3 - 960863 - - - -3.2673 - 2.317 0.391 - 197.4 1 2 0 -0.0041 11 0 0 0 2.09E+07 1.17E+07 - - - 5.2852 0.9996 221125_WJC_METTL3_EV_vs_WT_F06.09537.09537.3 0.0068 Jul-40 K.VHSVAWSC[160.03]DGR[166.11].R "sp|Q96J01|THOC3_HUMAN,tr|D6RGZ2|D6RGZ2_HUMAN" 2 1282.5752 0.78 79511 9537 3 1282.575389 428.5324 THO complex subunit 3 OS=Homo sapiens OX=9606 GN=THOC3 PE=1 SV=1 6.71 1967.3 - 941901 - - - 0.1286 - 1.621 0.373 - 97.4 1 2 0 0.0002 11 0 0 0 9.50E+06 1.22E+07 - - - 4.0708 0.9861 221125_WJC_METTL3_EV_vs_WT_F06.09542.09542.2 0.539 20-Jul K.IANPVEGSTDR.Q "sp|Q15366|PCBP2_HUMAN,tr|F8VRH0|F8VRH0_HUMAN,tr|F8VZX2|F8VZX2_HUMAN,tr|H3BRU6|H3BRU6_HUMAN,tr|H3BSS4|H3BSS4_HUMAN" 5 1157.5677 2.47 79516 9542 2 1157.566096 579.7911 Poly(rC)-binding protein 2 OS=Homo sapiens OX=9606 GN=PCBP2 PE=1 SV=1 4.37 1968 - 217828 - - - -1.3563 - 1.468 0.075 - 108.3 1 2 0 -0.0016 11 0 0 0 1.26E+07 5.12E+06 - - - 0.633 0.9994 221125_WJC_METTL3_EV_vs_WT_F06.09545.09545.3 0.00348 Aug-52 R.GNLGAGNGNLQGPR[166.11].H "sp|P43243|MATR3_HUMAN,tr|D6RE02|D6RE02_HUMAN,tr|B3KM87|B3KM87_HUMAN,tr|A8MXP9|A8MXP9_HUMAN,tr|D6RAY2|D6RAY2_HUMAN,tr|D6R991|D6R991_HUMAN,tr|A0A0R4J2E8|A0A0R4J2E8_HUMAN,tr|D6RAM9|D6RAM9_HUMAN,tr|D6RIA2|D6RIA2_HUMAN,tr|H0Y8T4|H0Y8T4_HUMAN,tr|D6REM6|D6REM6_HUMAN,tr|D6RBI2|D6RBI2_HUMAN" 12 1333.6726 1.47 79517 9545 3 1333.674018 445.5648 Matrin-3 OS=Homo sapiens OX=9606 GN=MATR3 PE=1 SV=2 9.75 1968.4 - 3.05E+06 - - - 1.0407 - 1.827 0.324 - 95.7 1 2 0 0.0014 14 0 0 0 4.52E+08 3.08E+08 - - - 3.7535 0.9907 221125_WJC_METTL3_EV_vs_WT_F06.09546.09546.3 0.0121 Aug-36 K.IK[136.11]EENFVSPK[136.11].E sp|O00425|IF2B3_HUMAN 1 1205.6627 1.51 79518 9546 3 1205.666265 402.8948 Insulin-like growth factor 2 mRNA-binding protein 3 OS=Homo sapiens OX=9606 GN=IGF2BP3 PE=1 SV=2 6.14 1968.4 - 1.97E+06 - - - 2.966 - 1.763 0.332 - 73.6 2 2 1 0.0036 10 0 0 0 2.18E+08 1.44E+08 - - - 3.7571 0.9998 221125_WJC_METTL3_EV_vs_WT_F06.09547.09547.3 0.00211 16/36 K.QVLQLQASHR.E "sp|Q9P2E9|RRBP1_HUMAN,tr|A0A087WVV2|A0A087WVV2_HUMAN,tr|F8W7S5|F8W7S5_HUMAN" 3 1178.652 1.32 79519 9547 3 1178.65109 393.8913 Ribosome-binding protein 1 OS=Homo sapiens OX=9606 GN=RRBP1 PE=1 SV=5 9.76 1968.5 - 1.14E+06 - - - -0.7755 - 2.31 0.327 - 310.3 1 2 0 -0.0009 10 0 0 0 1.06E+08 8.02E+07 - - - 4.6306 1 221125_WJC_METTL3_EV_vs_WT_F06.09549.09549.3 7.23E-08 17/56 K.IIDSDEGPEC[160.03]HPPVK.V sp|Q08554|DSC1_HUMAN 1 1691.7825 166.2 79521 9549 3 1691.783223 564.9348 Desmocollin-1 OS=Homo sapiens OX=9606 GN=DSC1 PE=1 SV=2 4.31 1968.8 - 754780 - - - 0.4356 - 2.816 0.603 - 303.1 1 2 0 0.0007 15 0 0 0 1.42E+08 8.55E+05 - - - 7.9642 0.9954 221125_WJC_METTL3_EV_vs_WT_F06.09551.09551.3 4.09E-07 14/40 F.VTFDDHDTVDK.L "sp|P51991|ROA3_HUMAN,tr|A0A7I2V5D8|A0A7I2V5D8_HUMAN,tr|A0A7I2V2R3|A0A7I2V2R3_HUMAN,tr|A0A7I2V4J6|A0A7I2V4J6_HUMAN,tr|A0A7I2V4G0|A0A7I2V4G0_HUMAN,tr|A0A7I2V402|A0A7I2V402_HUMAN" 6 1290.5728 1.28 79523 9551 3 1290.57401 431.1982 Heterogeneous nuclear ribonucleoprotein A3 OS=Homo sapiens OX=9606 GN=HNRNPA3 PE=1 SV=2 4.13 1969.1 - 604514 - - - 0.929 - 2.624 0.434 - 298.4 1 1 0 0.0012 11 0 0 0 1.20E+07 9.42E+06 - - - 6.1189 0.9994 221125_WJC_METTL3_EV_vs_WT_F06.09553.09553.2 0.000625 18-Jul K.GQEEVEMPSK[136.11].E "sp|Q14690|RRP5_HUMAN,tr|A0A3B3IUD7|A0A3B3IUD7_HUMAN" 2 1140.5212 1.08 79525 9553 2 1140.52022 571.2679 Protein RRP5 homolog OS=Homo sapiens OX=9606 GN=PDCD11 PE=1 SV=3 4.25 1969.3 - 336689 - - - -0.8935 - 1.497 0.391 - 117.2 1 2 0 -0.001 10 0 0 0 5.44E+06 5.02E+06 - - - 3.0548 0.9998 221125_WJC_METTL3_EV_vs_WT_F06.09554.09554.2 8.16E-05 13/22 K.ISNDNPEEHVLK.V "sp|Q9H2P0|ADNP_HUMAN,tr|A0A2R8Y6X0|A0A2R8Y6X0_HUMAN,tr|A0A669KBJ7|A0A669KBJ7_HUMAN" 3 1393.6838 0.79 79526 9554 2 1393.68664 697.8492 Activity-dependent neuroprotector homeobox protein OS=Homo sapiens OX=9606 GN=ADNP PE=1 SV=1 4.65 1969.4 - 323958 - - - 2.0679 - 2.509 0.525 - 329.8 1 2 0 0.0029 12 0 0 0 3.65E+06 4.64E+06 - - - 5.3381 0.9993 221125_WJC_METTL3_EV_vs_WT_F06.09556.09556.2 4.04E-05 18-Oct K.NPEHFVVC[160.03]NR.S sp|Q2TAY7|SMU1_HUMAN 1 1270.5877 1.48 79528 9556 2 1270.592086 636.3011 WD40 repeat-containing protein SMU1 OS=Homo sapiens OX=9606 GN=SMU1 PE=1 SV=2 6.74 1969.7 - 262550 - - - 3.4598 - 1.989 0.545 - 515.8 1 2 0 0.0044 10 0 0 0 1.09E+07 7.35E+06 - - - 4.9844 0.9972 221125_WJC_METTL3_EV_vs_WT_F06.09560.09560.3 0.117 Aug-40 K.HFVALSTNTTK[136.11].V "sp|P06744|G6PI_HUMAN,tr|A0A2R8Y6C7|A0A2R8Y6C7_HUMAN,tr|A0A0J9YYH3|A0A0J9YYH3_HUMAN,tr|K7EQ48|K7EQ48_HUMAN,tr|A0A2U3TZU2|A0A2U3TZU2_HUMAN,tr|A0A0J9YXP8|A0A0J9YXP8_HUMAN,tr|A0A0J9YX90|A0A0J9YX90_HUMAN" 7 1225.6546 0.74 79530 9560 3 1225.654373 409.5588 Glucose-6-phosphate isomerase OS=Homo sapiens OX=9606 GN=GPI PE=1 SV=4 8.76 1970.1 - 1.69E+06 - - - -0.2154 - 1.456 0.269 - 77.4 1 2 0 -0.0003 11 0 0 0 1.14E+07 1.53E+07 - - - 2.6063 1 221125_WJC_METTL3_EV_vs_WT_F06.09561.09561.3 2.90E-05 Dec-56 K.VLGLAHSTTGPQESK.G "sp|Q14865|ARI5B_HUMAN,tr|A0A7P0TAD2|A0A7P0TAD2_HUMAN" 2 1523.7944 0.82 79531 9561 3 1523.795295 508.9387 AT-rich interactive domain-containing protein 5B OS=Homo sapiens OX=9606 GN=ARID5B PE=1 SV=3 6.72 1970.3 - 715998 - - - 0.6064 - 2.623 0.475 - 157.9 1 2 0 0.0009 15 0 0 0 1.77E+07 2.15E+07 - - - 6.3518 0.9994 221125_WJC_METTL3_EV_vs_WT_F06.09562.09562.3 0.000616 Oct-36 K.NPEHFVVC[160.03]NR.S sp|Q2TAY7|SMU1_HUMAN 1 1270.5877 1.42 79532 9562 3 1270.586557 424.5365 WD40 repeat-containing protein SMU1 OS=Homo sapiens OX=9606 GN=SMU1 PE=1 SV=2 6.74 1970.3 - 1.60E+06 - - - -0.8917 - 1.745 0.312 - 199.5 1 2 0 -0.0011 10 0 0 0 3.09E+07 2.18E+07 - - - 3.6441 0.9978 221125_WJC_METTL3_EV_vs_WT_F06.09565.09565.2 0.0151 18-Aug K.GQEEVEMPSK.E "sp|Q14690|RRP5_HUMAN,tr|A0A3B3IUD7|A0A3B3IUD7_HUMAN" 2 1132.507 1.12 79535 9565 2 1132.504347 567.2608 Protein RRP5 homolog OS=Homo sapiens OX=9606 GN=PDCD11 PE=1 SV=3 4.25 1970.7 - 535166 - - - -2.377 - 1.403 0.352 - 116.2 1 2 0 -0.0027 10 0 0 0 5.44E+06 4.85E+06 - - - 2.5852 0.9999 221125_WJC_METTL3_EV_vs_WT_F06.09568.09568.2 3.08E-06 13/18 K.NPEHFVVC[160.03]NR[166.11].S sp|Q2TAY7|SMU1_HUMAN 1 1280.596 1.53 79537 9568 2 1280.59679 641.3053 WD40 repeat-containing protein SMU1 OS=Homo sapiens OX=9606 GN=SMU1 PE=1 SV=2 6.74 1971.1 - 531138 - - - 0.6481 - 2.139 0.546 - 861.3 1 2 0 0.0008 10 0 0 0 1.13E+07 7.35E+06 - - - 5.1958 1 221125_WJC_METTL3_EV_vs_WT_F06.09570.09570.2 4.53E-06 15/26 R.GNLGAGNGNLQGPR[166.11].H "sp|P43243|MATR3_HUMAN,tr|D6RE02|D6RE02_HUMAN,tr|B3KM87|B3KM87_HUMAN,tr|A8MXP9|A8MXP9_HUMAN,tr|D6RAY2|D6RAY2_HUMAN,tr|D6R991|D6R991_HUMAN,tr|A0A0R4J2E8|A0A0R4J2E8_HUMAN,tr|D6RAM9|D6RAM9_HUMAN,tr|D6RIA2|D6RIA2_HUMAN,tr|H0Y8T4|H0Y8T4_HUMAN,tr|D6REM6|D6REM6_HUMAN,tr|D6RBI2|D6RBI2_HUMAN" 12 1333.6726 1.38 79538 9570 2 1333.671241 667.8436 Matrin-3 OS=Homo sapiens OX=9606 GN=MATR3 PE=1 SV=2 9.75 1971.3 - 1.59E+08 - - - -1.0415 - 2.765 0.568 - 795.4 1 2 0 -0.0014 14 0 0 0 1.01E+10 7.35E+09 - - - 5.788 0.9999 221125_WJC_METTL3_EV_vs_WT_F06.09574.09574.3 2.33E-05 Nov-36 K.VEHSDLSFSK[136.11].D "sp|P61769|B2MG_HUMAN,tr|H0YLF3|H0YLF3_HUMAN,tr|F5H6I0|F5H6I0_HUMAN" 3 1155.5652 2.06 79542 9574 3 1155.563541 386.1957 Beta-2-microglobulin OS=Homo sapiens OX=9606 GN=B2M PE=1 SV=1 5.32 1971.6 - 1.77E+06 - - - -1.395 - 2.204 0.423 - 142.8 1 2 0 -0.0016 10 0 0 0 6.52E+07 3.16E+07 - - - 5.5635 0.9906 221125_WJC_METTL3_EV_vs_WT_F06.09576.09576.2 0.00317 18-Dec K.QVLQLQASHR.E "sp|Q9P2E9|RRBP1_HUMAN,tr|A0A087WVV2|A0A087WVV2_HUMAN,tr|F8W7S5|F8W7S5_HUMAN" 3 1178.652 1.26 79544 9576 2 1178.658971 590.3333 Ribosome-binding protein 1 OS=Homo sapiens OX=9606 GN=RRBP1 PE=1 SV=5 9.76 1971.9 - 761577 - - - 5.911 - 2.323 0.32 - 687.3 1 2 0 0.007 10 0 0 0 1.86E+07 1.48E+07 - - - 3.755 0.9905 221125_WJC_METTL3_EV_vs_WT_F06.09577.09577.2 0.0958 18-Aug K.R[166.11]PSAPVDFSK[136.11].L sp|Q14696|MESD_HUMAN 1 1120.5996 1.02 79545 9577 2 1120.599987 561.3071 LRP chaperone MESD OS=Homo sapiens OX=9606 GN=MESD PE=1 SV=2 8.75 1972 - 527773 - - - 0.365 - 1.718 0.037 - 246.6 2 2 0 0.0004 10 0 0 0 6.19E+06 6.07E+06 - - - 0.6902 0.9992 221125_WJC_METTL3_EV_vs_WT_F06.09580.09580.3 0.299 13/36 K.VEHSDLSFSK.D "sp|P61769|B2MG_HUMAN,tr|H0YLF3|H0YLF3_HUMAN,tr|F5H6I0|F5H6I0_HUMAN" 3 1147.551 2.07 79546 9580 3 1147.549146 383.5243 Beta-2-microglobulin OS=Homo sapiens OX=9606 GN=B2M PE=1 SV=1 5.32 1972.4 - 3.61E+06 - - - -1.5747 - 2 0.278 - 203.9 1 2 0 -0.0018 10 0 0 0 6.52E+07 3.15E+07 - - - 3.6632 0.9998 221125_WJC_METTL3_EV_vs_WT_F06.09582.09582.3 0.00103 13/40 K.AQLGLGHSYSR[166.11].A "sp|O00567|NOP56_HUMAN,tr|A0A494C128|A0A494C128_HUMAN,tr|Q5JXT2|Q5JXT2_HUMAN" 3 1197.613 1.06 79548 9582 3 1197.610425 400.2116 Nucleolar protein 56 OS=Homo sapiens OX=9606 GN=NOP56 PE=1 SV=4 8.8 1972.5 - 1.72E+06 - - - -2.1418 - 2.662 0.368 - 295.9 1 2 0 -0.0026 11 0 0 0 2.90E+07 2.75E+07 - - - 5.4235 0.9999 221125_WJC_METTL3_EV_vs_WT_F06.09585.09585.2 3.41E-06 28-Nov K.EASDPQPEEADGGLK.S sp|P52907|CAZA1_HUMAN 1 1541.6845 1.11 79551 9585 2 1541.682719 771.8495 F-actin-capping protein subunit alpha-1 OS=Homo sapiens OX=9606 GN=CAPZA1 PE=1 SV=3 3.83 1972.9 - 513272 - - - -1.1851 - 2.142 0.549 - 174.1 1 2 0 -0.0018 15 0 0 0 4.63E+07 4.17E+07 - - - 4.9681 0.9911 221125_WJC_METTL3_EV_vs_WT_F06.09586.09586.2 3.86E-05 14/22 N.LGAGNGNLQGPR[166.11].H "sp|P43243|MATR3_HUMAN,tr|D6RE02|D6RE02_HUMAN,tr|B3KM87|B3KM87_HUMAN,tr|A8MXP9|A8MXP9_HUMAN,tr|D6RAY2|D6RAY2_HUMAN,tr|D6R991|D6R991_HUMAN,tr|A0A0R4J2E8|A0A0R4J2E8_HUMAN,tr|D6RAM9|D6RAM9_HUMAN,tr|D6RIA2|D6RIA2_HUMAN,tr|H0Y8T4|H0Y8T4_HUMAN,tr|D6REM6|D6REM6_HUMAN,tr|D6RBI2|D6RBI2_HUMAN" 12 1162.6082 1.05 79552 9586 2 1162.609908 582.3114 Matrin-3 OS=Homo sapiens OX=9606 GN=MATR3 PE=1 SV=2 9.75 1973 - 459312 - - - 1.4356 - 2.841 0.498 - 772.8 1 1 0 0.0017 12 0 0 0 9.03E+06 8.56E+06 - - - 5.4661 0.9991 221125_WJC_METTL3_EV_vs_WT_F06.09588.09588.3 0.0049 Jul-44 R.GFYPQSHQEPVK.H sp|P0C7T5|ATX1L_HUMAN 1 1415.6834 1.92 79553 9588 3 1415.681321 472.9017 Ataxin-1-like OS=Homo sapiens OX=9606 GN=ATXN1L PE=1 SV=1 6.75 1973.3 - 2.30E+06 - - - -1.4431 - 1.651 0.327 - 49 1 2 0 -0.002 12 0 0 0 6.55E+07 3.41E+07 - - - 3.5749 0.9938 221125_WJC_METTL3_EV_vs_WT_F06.09594.09594.2 0.00622 18-Oct K.IKEENFVSPK.E sp|O00425|IF2B3_HUMAN 1 1189.6343 1.44 79558 9594 2 1189.634339 595.8244 Insulin-like growth factor 2 mRNA-binding protein 3 OS=Homo sapiens OX=9606 GN=IGF2BP3 PE=1 SV=2 6.14 1973.7 - 1.81E+06 - - - 0.042 - 1.716 0.32 - 251.7 1 2 1 0.0001 10 0 0 0 4.43E+07 3.07E+07 - - - 2.9118 1 221125_WJC_METTL3_EV_vs_WT_F06.09595.09595.3 8.23E-06 18/68 K.ALVSGKPAESSAVAATEK.K sp|O95182|NDUA7_HUMAN 1 1714.9101 2.22 79559 9595 3 1714.910767 572.644 NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 7 OS=Homo sapiens OX=9606 GN=NDUFA7 PE=1 SV=3 6.19 1973.9 - 1.36E+06 - - - 0.372 - 3.095 0.536 - 249.9 1 2 0 0.0006 18 0 0 0 2.18E+07 9.85E+06 - - - 7.329 0.966 221125_WJC_METTL3_EV_vs_WT_F06.09597.09597.2 0.329 18-Aug R.IRDLNDEINK.L "sp|Q9ULR0|ISY1_HUMAN,tr|D6RC18|D6RC18_HUMAN,tr|A8MVI5|A8MVI5_HUMAN,tr|H0YA89|H0YA89_HUMAN" 4 1228.6412 0.32 79561 9597 2 1228.641966 615.3279 Pre-mRNA-splicing factor ISY1 homolog OS=Homo sapiens OX=9606 GN=ISY1 PE=1 SV=3 4.56 1974.1 - 1.01E+06 - - - 0.6519 - 1.801 0.117 - 191.9 1 2 1 0.0008 10 0 0 0 8.40E+06 2.59E+07 - - - 1.5472 1 221125_WJC_METTL3_EV_vs_WT_F06.09607.09607.2 1.17E-08 17/28 K.EASDPQPEEADGGLK[136.11].S sp|P52907|CAZA1_HUMAN 1 1549.6987 1.11 79569 9607 2 1550.694405 775.8566 F-actin-capping protein subunit alpha-1 OS=Homo sapiens OX=9606 GN=CAPZA1 PE=1 SV=3 3.83 1975.3 - 1.32E+06 - - - 642.4855 - 2.789 0.663 - 631.8 1 2 0 0.9957 15 0 0 0 4.63E+07 4.17E+07 - - - 6.147 0.9902 221125_WJC_METTL3_EV_vs_WT_F06.09610.09610.3 0.0103 Sep-44 K.ISSDLDGHPVPK.Q "sp|P29401|TKT_HUMAN,tr|E9PFF2|E9PFF2_HUMAN,tr|F8W888|F8W888_HUMAN" 3 1263.6459 1.06 79572 9610 3 1263.641269 422.2226 Transketolase OS=Homo sapiens OX=9606 GN=TKT PE=1 SV=3 5.21 1975.7 - 567948 - - - -3.6775 - 1.677 0.27 - 76.3 1 2 0 -0.0046 12 0 0 0 2.03E+07 1.91E+07 - - - 2.982 0.9951 221125_WJC_METTL3_EV_vs_WT_F06.09613.09613.2 0.0444 18-Oct K.IK[136.11]EENFVSPK[136.11].E sp|O00425|IF2B3_HUMAN 1 1205.6627 1.44 79573 9613 2 1205.663815 603.8386 Insulin-like growth factor 2 mRNA-binding protein 3 OS=Homo sapiens OX=9606 GN=IGF2BP3 PE=1 SV=2 6.14 1976.1 - 1.46E+06 - - - 0.9339 - 1.978 0.337 - 226.3 1 2 1 0.0011 10 0 0 0 4.41E+07 3.07E+07 - - - 3.4336 0.9994 221125_WJC_METTL3_EV_vs_WT_F06.09614.09614.2 0.0163 18-Sep K.EKPTTALLDK.V "sp|Q12906|ILF3_HUMAN,tr|K7ER69|K7ER69_HUMAN,tr|K7EKY0|K7EKY0_HUMAN,tr|K7EKJ9|K7EKJ9_HUMAN" 4 1114.6234 0.9 79574 9614 2 1114.622739 558.319 Interleukin enhancer-binding factor 3 OS=Homo sapiens OX=9606 GN=ILF3 PE=1 SV=3 6.17 1976.2 - 362166 - - - -0.5841 - 1.76 0.309 - 167.9 1 2 0 -0.0006 10 0 0 0 7.92E+06 8.82E+06 - - - 2.901 0.9735 221125_WJC_METTL3_EV_vs_WT_F06.09615.09615.2 0.000901 16-Nov R.K[136.11]QDSGHLDL.R "sp|Q86U44|MTA70_HUMAN,tr|B4E349|B4E349_HUMAN,tr|F5H6D8|F5H6D8_HUMAN,tr|B4DTN4|B4DTN4_HUMAN" 4 1019.5127 0.02 79575 9615 2 1019.511667 510.7636 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 5.21 1976.3 - 2.02E+06 - - - -1.0358 - 1.684 0.377 - 302.5 1 1 0 -0.0011 9 0 0 0 6.69E+05 4.15E+07 - - - 3.333 1 221125_WJC_METTL3_EV_vs_WT_F06.09616.09616.3 9.66E-05 14/36 K.THEDIEAQIR[166.11].E "sp|O75533|SF3B1_HUMAN,tr|B4DGZ4|B4DGZ4_HUMAN,tr|F8WC19|F8WC19_HUMAN,tr|A0A494C1M2|A0A494C1M2_HUMAN" 4 1220.6025 0.74 79576 9616 3 1220.601528 407.8748 Splicing factor 3B subunit 1 OS=Homo sapiens OX=9606 GN=SF3B1 PE=1 SV=3 4.65 1976.4 - 1.90E+06 - - - -0.784 - 2.657 0.504 - 382.7 1 2 0 -0.001 10 0 0 0 9.36E+07 1.26E+08 - - - 7.0127 0.9997 221125_WJC_METTL3_EV_vs_WT_F06.09622.09622.3 0.00458 Nov-52 R.GNLGAGNGNLQGPR.H "sp|P43243|MATR3_HUMAN,tr|D6RE02|D6RE02_HUMAN,tr|B3KM87|B3KM87_HUMAN,tr|A8MXP9|A8MXP9_HUMAN,tr|D6RAY2|D6RAY2_HUMAN,tr|D6R991|D6R991_HUMAN,tr|A0A0R4J2E8|A0A0R4J2E8_HUMAN,tr|D6RAM9|D6RAM9_HUMAN,tr|D6RIA2|D6RIA2_HUMAN,tr|H0Y8T4|H0Y8T4_HUMAN,tr|D6REM6|D6REM6_HUMAN,tr|D6RBI2|D6RBI2_HUMAN" 12 1323.6644 1.48 79581 9622 3 1323.662823 442.2287 Matrin-3 OS=Homo sapiens OX=9606 GN=MATR3 PE=1 SV=2 9.75 1977.1 - 2.66E+07 - - - -1.1612 - 2.042 0.358 - 170.3 1 2 0 -0.0015 14 0 0 0 4.56E+08 3.08E+08 - - - 4.4282 1 221125_WJC_METTL3_EV_vs_WT_F06.09625.09625.3 1.44E-06 13/44 K.EAPPMEKPEVVK.T "sp|P62841|RS15_HUMAN,tr|K7EJ78|K7EJ78_HUMAN,tr|K7EM56|K7EM56_HUMAN,tr|A0A0B4J2B4|A0A0B4J2B4_HUMAN,tr|S4R456|S4R456_HUMAN,tr|K7ELC2|K7ELC2_HUMAN,tr|K7EQJ5|K7EQJ5_HUMAN,tr|S4R417|S4R417_HUMAN" 8 1352.701 1.29 79583 9625 3 1352.700545 451.9076 40S ribosomal protein S15 OS=Homo sapiens OX=9606 GN=RPS15 PE=1 SV=2 4.79 1977.4 - 4.45E+06 - - - -0.3275 - 2.713 0.43 - 304.6 1 2 0 -0.0004 12 0 0 0 3.57E+08 2.76E+08 - - - 6.1004 0.9999 221125_WJC_METTL3_EV_vs_WT_F06.09626.09626.3 0.0019 13/40 K.QHLEITGGQVR.T "sp|P47897|SYQ_HUMAN,tr|B4DDN1|B4DDN1_HUMAN,tr|C9J165|C9J165_HUMAN,tr|A0A1B0GVU9|A0A1B0GVU9_HUMAN,tr|A0A0U1RR66|A0A0U1RR66_HUMAN" 5 1236.6575 0.88 79584 9626 3 1236.659016 413.2264 Glutamine--tRNA ligase OS=Homo sapiens OX=9606 GN=QARS1 PE=1 SV=1 6.75 1977.5 - 2.36E+06 - - - 1.2388 - 2.112 0.394 - 251 1 2 0 0.0015 11 0 0 0 6.43E+07 7.31E+07 - - - 5.0562 0.9505 221125_WJC_METTL3_EV_vs_WT_F06.09628.09628.2 0.0221 16-Sep K.EKEHYQVLE.- "sp|Q86UP2|KTN1_HUMAN,tr|B7Z6P3|B7Z6P3_HUMAN,tr|G3V4Y7|G3V4Y7_HUMAN" 3 1173.5666 2.08 79586 9628 2 1173.56359 587.7906 Kinectin OS=Homo sapiens OX=9606 GN=KTN1 PE=1 SV=1 4.96 1977.7 - 1.52E+06 - - - -2.5674 - 1.5 0.251 - 249.1 1 2 1 -0.003 9 0 0 0 1.52E+07 7.30E+06 - - - 2.067 0.9993 221125_WJC_METTL3_EV_vs_WT_F06.09629.09629.2 7.30E-07 13/20 R.TAIHEVMEQGR[166.11].V "sp|P25205|MCM3_HUMAN,tr|J3KQ69|J3KQ69_HUMAN,tr|A0A499FHX9|A0A499FHX9_HUMAN" 3 1279.6218 0.68 79587 9629 2 1279.6172 640.8182 DNA replication licensing factor MCM3 OS=Homo sapiens OX=9606 GN=MCM3 PE=1 SV=3 5.37 1977.8 - 1.48E+06 - - - -3.6261 - 2.544 0.517 - 671.3 1 2 0 -0.0046 11 0 0 0 3.48E+07 5.11E+07 - - - 5.3841 0.9995 221125_WJC_METTL3_EV_vs_WT_F06.09630.09630.2 0.00222 20-Nov K.QHLEITGGQVR.T "sp|P47897|SYQ_HUMAN,tr|B4DDN1|B4DDN1_HUMAN,tr|C9J165|C9J165_HUMAN,tr|A0A1B0GVU9|A0A1B0GVU9_HUMAN,tr|A0A0U1RR66|A0A0U1RR66_HUMAN" 5 1236.6575 1.05 79588 9630 2 1236.655088 619.336 Glutamine--tRNA ligase OS=Homo sapiens OX=9606 GN=QARS1 PE=1 SV=1 6.75 1977.9 - 937664 - - - -1.9375 - 1.916 0.404 - 428 1 2 0 -0.0024 11 0 0 0 2.92E+07 2.79E+07 - - - 3.7832 0.9987 221125_WJC_METTL3_EV_vs_WT_F06.09631.09631.2 0.0058 20-Aug R.TAIHEVMEQGR.V "sp|P25205|MCM3_HUMAN,tr|J3KQ69|J3KQ69_HUMAN,tr|A0A499FHX9|A0A499FHX9_HUMAN" 3 1269.6136 0.64 79589 9631 2 1269.608937 635.8141 DNA replication licensing factor MCM3 OS=Homo sapiens OX=9606 GN=MCM3 PE=1 SV=3 5.37 1978 - 846592 - - - -3.6491 - 2.063 0.439 - 217.9 1 2 0 -0.0046 11 0 0 0 3.22E+07 5.05E+07 - - - 4.241 1 221125_WJC_METTL3_EV_vs_WT_F06.09634.09634.3 6.20E-05 13/40 R.TAIHEVMEQGR[166.11].V "sp|P25205|MCM3_HUMAN,tr|J3KQ69|J3KQ69_HUMAN,tr|A0A499FHX9|A0A499FHX9_HUMAN" 3 1279.6218 0.54 79590 9634 3 1279.62058 427.5479 DNA replication licensing factor MCM3 OS=Homo sapiens OX=9606 GN=MCM3 PE=1 SV=3 5.37 1978.4 - 2.66E+06 - - - -0.9847 - 2.489 0.46 - 396.9 1 2 0 -0.0013 11 0 0 0 2.89E+07 5.38E+07 - - - 6.2587 0.9998 221125_WJC_METTL3_EV_vs_WT_F06.09636.09636.2 3.24E-07 13/22 K.GSDGAASSYQLK.Q "sp|Q14203|DCTN1_HUMAN,tr|A0A804CDA6|A0A804CDA6_HUMAN,tr|E7EX90|E7EX90_HUMAN,tr|A0A7P0Z4C3|A0A7P0Z4C3_HUMAN,tr|Q6AWB1|Q6AWB1_HUMAN" 5 1182.5517 1.97 79592 9636 2 1182.549408 592.2831 Dynactin subunit 1 OS=Homo sapiens OX=9606 GN=DCTN1 PE=1 SV=3 5.83 1978.6 - 725728 - - - -1.9221 - 2.707 0.528 - 610.6 1 2 0 -0.0023 12 0 0 0 1.34E+08 6.81E+07 - - - 5.5603 0.9996 221125_WJC_METTL3_EV_vs_WT_F06.09640.09640.2 0.0158 20-Nov K.QHLEITGGQVR[166.11].T "sp|P47897|SYQ_HUMAN,tr|B4DDN1|B4DDN1_HUMAN,tr|C9J165|C9J165_HUMAN,tr|A0A1B0GVU9|A0A1B0GVU9_HUMAN,tr|A0A0U1RR66|A0A0U1RR66_HUMAN" 5 1246.6658 1.05 79594 9640 2 1246.664251 624.3402 Glutamine--tRNA ligase OS=Homo sapiens OX=9606 GN=QARS1 PE=1 SV=1 6.75 1979.1 - 1.36E+06 - - - -1.2056 - 1.976 0.37 - 424.6 1 2 0 -0.0015 11 0 0 0 3.02E+07 2.88E+07 - - - 3.6158 1 221125_WJC_METTL3_EV_vs_WT_F06.09641.09641.3 0.000624 Nov-36 K.THEDIEAQIR.E "sp|O75533|SF3B1_HUMAN,tr|B4DGZ4|B4DGZ4_HUMAN,tr|F8WC19|F8WC19_HUMAN,tr|A0A494C1M2|A0A494C1M2_HUMAN" 4 1210.5942 0.74 79595 9641 3 1210.592392 404.5387 Splicing factor 3B subunit 1 OS=Homo sapiens OX=9606 GN=SF3B1 PE=1 SV=3 4.65 1979.2 - 6.76E+06 - - - -1.5059 - 2.551 0.508 - 304 1 2 0 -0.0018 10 0 0 0 9.13E+07 1.24E+08 - - - 6.9381 0.9981 221125_WJC_METTL3_EV_vs_WT_F06.09648.09648.2 0.0796 24-Aug K.ETPPNGNLSPAPR[166.11].L sp|P48634|PRC2A_HUMAN 1 1358.6818 0.55 79602 9648 2 1358.68035 680.3482 Protein PRRC2A OS=Homo sapiens OX=9606 GN=PRRC2A PE=1 SV=3 6.1 1979.9 - 728107 - - - -1.0657 - 1.558 0.248 - 85.5 1 2 0 -0.0014 13 0 0 0 1.02E+07 1.85E+07 - - - 2.0103 0.9993 221125_WJC_METTL3_EV_vs_WT_F06.09649.09649.3 0.000809 13/40 R.SVC[160.03]LIGDKEQR.A sp|O60264|SMCA5_HUMAN 1 1303.6554 0.62 79603 9649 3 1303.653406 435.5591 SWI\SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A member 5 OS=Homo sapiens OX=9606 GN=SMARCA5 PE=1 SV=1 5.79 1980 - 711534 - - - -1.5564 - 2.482 0.36 - 225.6 1 2 1 -0.002 11 0 0 0 1.02E+07 1.64E+07 - - - 5.1356 1 221125_WJC_METTL3_EV_vs_WT_F06.09652.09652.2 8.30E-09 14/26 K.AVTEQGAELSNEER.N "sp|P27348|1433T_HUMAN,tr|E9PG15|E9PG15_HUMAN" 2 1531.7114 1.11 79604 9652 2 1531.711143 766.863 14-3-3 protein theta OS=Homo sapiens OX=9606 GN=YWHAQ PE=1 SV=1 4.09 1980.5 - 2.37E+06 - - - -0.1874 - 3.284 0.619 - 727.1 1 2 0 -0.0003 14 0 0 0 1.72E+08 1.56E+08 - - - 6.5967 0.9996 221125_WJC_METTL3_EV_vs_WT_F06.09653.09653.3 2.24E-05 16/52 R.IVEDEPNK[136.11]IC[160.03]EADR[166.11].V sp|P55060|XPO2_HUMAN 1 1704.8108 1.19 79605 9653 3 1704.805965 569.2775 Exportin-2 OS=Homo sapiens OX=9606 GN=CSE1L PE=1 SV=3 4.18 1980.6 - 431193 - - - -2.8185 - 2.514 0.497 - 116.2 1 2 1 -0.0048 14 0 0 0 8.33E+06 6.97E+06 - - - 6.5296 0.9999 221125_WJC_METTL3_EV_vs_WT_F06.09655.09655.2 4.92E-06 14/22 K.GSDGAASSYQLK[136.11].Q "sp|Q14203|DCTN1_HUMAN,tr|A0A804CDA6|A0A804CDA6_HUMAN,tr|E7EX90|E7EX90_HUMAN,tr|A0A7P0Z4C3|A0A7P0Z4C3_HUMAN,tr|Q6AWB1|Q6AWB1_HUMAN" 5 1190.5659 1.97 79607 9655 2 1190.565276 596.2902 Dynactin subunit 1 OS=Homo sapiens OX=9606 GN=DCTN1 PE=1 SV=3 5.83 1980.7 - 2.19E+06 - - - -0.5082 - 1.888 0.524 - 495.2 1 2 0 -0.0006 12 0 0 0 1.34E+08 6.81E+07 - - - 4.5832 1 221125_WJC_METTL3_EV_vs_WT_F06.09658.09658.2 1.10E-07 24-Nov K.TFQGPNC[160.03]PATC[160.03]GR.V "sp|Q13685|AAMP_HUMAN,tr|C9JG97|C9JG97_HUMAN,tr|C9JEH3|C9JEH3_HUMAN,tr|C9JTS3|C9JTS3_HUMAN" 4 1464.6238 0.9 79610 9658 2 1464.623157 733.3192 Angio-associated migratory cell protein OS=Homo sapiens OX=9606 GN=AAMP PE=1 SV=2 7.75 1981 - 772160 - - - -0.4513 - 2.226 0.7 - 402.2 1 2 0 -0.0007 13 0 0 0 2.00E+07 2.22E+07 - - - 6.2647 0.9183 221125_WJC_METTL3_EV_vs_WT_F06.09660.09660.2 0.00303 18-Nov R.QPIKQELIC[160.03]K.W "sp|Q8N9L1|ZIC4_HUMAN,sp|Q96T25|ZIC5_HUMAN,sp|Q15915|ZIC1_HUMAN,tr|C9JD04|C9JD04_HUMAN" 4 1255.6958 1.95 79612 9660 2 1255.689387 628.8552 Zinc finger protein ZIC 4 OS=Homo sapiens OX=9606 GN=ZIC4 PE=2 SV=3 8.2 1981.3 - 553862 - - - -5.1414 - 1.616 0.4 - 255.1 1 2 1 -0.0065 10 0 0 0 7.55E+06 3.87E+06 - - - 3.3331 0.9997 221125_WJC_METTL3_EV_vs_WT_F06.09667.09667.3 0.000373 Dec-36 R.NGVMPSHFSR[166.11].G "sp|P39019|RS19_HUMAN,tr|A0A075B6E2|A0A075B6E2_HUMAN" 2 1140.5374 0.001 79617 9667 3 1140.536629 381.1864 40S ribosomal protein S19 OS=Homo sapiens OX=9606 GN=RPS19 PE=1 SV=2 9.76 1982.2 - 910519 - - - -0.6602 - 2.508 0.259 - 345.3 1 2 0 -0.0008 10 0 0 0 0.00E+00 1.15E+09 - - - 4.1127 1 221125_WJC_METTL3_EV_vs_WT_F06.09669.09669.2 9.44E-11 14/24 K.TFQGPNC[160.03]PATC[160.03]GR[166.11].V "sp|Q13685|AAMP_HUMAN,tr|C9JG97|C9JG97_HUMAN,tr|C9JEH3|C9JEH3_HUMAN,tr|C9JTS3|C9JTS3_HUMAN" 4 1474.6321 0.9 79619 9669 2 1474.634358 738.3233 Angio-associated migratory cell protein OS=Homo sapiens OX=9606 GN=AAMP PE=1 SV=2 7.75 1982.4 - 611935 - - - 1.5394 - 2.627 0.704 - 672.8 1 2 0 0.0023 13 0 0 0 2.00E+07 2.22E+07 - - - 6.7189 0.8622 221125_WJC_METTL3_EV_vs_WT_F06.09671.09671.2 1.39 28-May R.TAGGMAVAGTATGPR.T sp|Q8TC56|FA71B_HUMAN 1 1316.6507 1.23 79621 9671 2 1316.649979 659.3326 Protein FAM71B OS=Homo sapiens OX=9606 GN=FAM71B PE=1 SV=2 9.41 1982.7 - 172991 - - - -0.5354 - 1.069 0.024 - 52 12 2 0 -0.0007 15 0 0 0 8.64E+06 7.00E+06 - - - -1.1 0.9818 221125_WJC_METTL3_EV_vs_WT_F06.09673.09673.2 0.0207 22-Jul K.YIC[160.03]ENQDSISSK.L "sp|P02768|ALBU_HUMAN,tr|B7WNR0|B7WNR0_HUMAN,tr|H0YA55|H0YA55_HUMAN,tr|A0A0C4DGB6|A0A0C4DGB6_HUMAN,tr|D6RHD5|D6RHD5_HUMAN,tr|C9JKR2|C9JKR2_HUMAN" 6 1442.6348 999 79622 9673 2 1442.633527 722.3247 Albumin OS=Homo sapiens OX=9606 GN=ALB PE=1 SV=2 4.37 1982.9 - 5.89E+06 - - - -0.854 - 1.185 0.11 - 108.1 1 2 0 -0.0012 12 0 0 0 7.14E+07 0.00E+00 - - - 0.2997 1 221125_WJC_METTL3_EV_vs_WT_F06.09675.09675.2 2.35E-07 15/26 K.AVTEQGAELSNEER[166.11].N "sp|P27348|1433T_HUMAN,tr|E9PG15|E9PG15_HUMAN" 2 1541.7197 1.11 79624 9675 2 1541.721319 771.8671 14-3-3 protein theta OS=Homo sapiens OX=9606 GN=YWHAQ PE=1 SV=1 4.09 1983 - 6.39E+06 - - - 1.0501 - 3.292 0.554 - 834.1 1 2 0 0.0016 14 0 0 0 1.72E+08 1.56E+08 - - - 6.1223 0.9923 221125_WJC_METTL3_EV_vs_WT_F06.09676.09676.2 0.000376 14-Oct T.GHWLNHGK[136.11].E sp|Q86U44|MTA70_HUMAN 1 955.4868 0.02 79625 9676 2 955.486474 478.7507 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 8.76 1983.1 - 4.67E+06 - - - -0.3234 - 1.874 0.514 - 410 1 1 0 -0.0003 8 0 0 0 1.52E+06 8.27E+07 - - - 4.7316 0.9998 221125_WJC_METTL3_EV_vs_WT_F06.09677.09677.3 0.0506 Nov-52 K.AVTEQGAELSNEER.N "sp|P27348|1433T_HUMAN,tr|E9PG15|E9PG15_HUMAN" 2 1531.7114 1.13 79626 9677 3 1531.711356 511.5778 14-3-3 protein theta OS=Homo sapiens OX=9606 GN=YWHAQ PE=1 SV=1 4.09 1983.1 - 1.62E+06 - - - -0.0483 - 2.447 0.317 - 184.7 1 2 0 -0.0001 14 0 0 0 3.42E+07 3.03E+07 - - - 4.4523 0.9991 221125_WJC_METTL3_EV_vs_WT_F06.09678.09678.2 0.00043 16-Aug K.AQYEEIANR.S "sp|P13647|K2C5_HUMAN,tr|H0YI76|H0YI76_HUMAN,tr|H0YIN9|H0YIN9_HUMAN" 3 1092.52 34.11 79627 9678 2 1092.522506 547.2673 "Keratin, type II cytoskeletal 5 OS=Homo sapiens OX=9606 GN=KRT5 PE=1 SV=3" 4.53 1983.2 - 901861 - - - 2.3057 - 1.559 0.433 - 234 1 2 0 0.0025 9 0 0 0 5.01E+07 1.47E+06 - - - 3.523 0.9993 221125_WJC_METTL3_EV_vs_WT_F06.09679.09679.2 0.00177 24-Oct K.ETPPNGNLSPAPR.L sp|P48634|PRC2A_HUMAN 1 1348.6735 0.04 79628 9679 2 1348.676044 675.344 Protein PRRC2A OS=Homo sapiens OX=9606 GN=PRRC2A PE=1 SV=3 6.1 1983.4 - 536549 - - - 1.8655 - 1.746 0.408 - 160.8 1 2 0 0.0025 13 0 0 0 3.16E+07 8.10E+08 - - - 3.4841 0.9098 221125_WJC_METTL3_EV_vs_WT_F06.09683.09683.2 1.04 18-Jul K.LR[166.11]ETLEEYNK[136.11].E "sp|Q13948|CASP_HUMAN,sp|P39880|CUX1_HUMAN,tr|A0A2R8Y852|A0A2R8Y852_HUMAN,tr|A0A2R8YDI1|A0A2R8YDI1_HUMAN" 4 1311.679 0.83 79632 9683 2 1311.678139 656.8468 Protein CASP OS=Homo sapiens OX=9606 GN=CUX1 PE=1 SV=2 4.79 1983.9 - 251674 - - - -0.6191 - 1.209 0.159 - 142.2 1 2 1 -0.0008 10 0 0 0 4.82E+06 5.80E+06 - - - 0.7449 0.9987 221125_WJC_METTL3_EV_vs_WT_F06.09686.09686.3 0.00312 Nov-40 K.TK[136.11]EGVLYVGSK[136.11].T "sp|Q16143|SYUB_HUMAN,sp|P37840|SYUA_HUMAN,tr|A0A669KB41|A0A669KB41_HUMAN,tr|D6RA31|D6RA31_HUMAN,tr|A0A669KBH5|A0A669KBH5_HUMAN,tr|E7EPV7|E7EPV7_HUMAN" 6 1195.6783 1.4 79633 9686 3 1195.678173 399.5667 Beta-synuclein OS=Homo sapiens OX=9606 GN=SNCB PE=1 SV=1 8.17 1984.3 - 4.08E+06 - - - -0.1388 - 1.824 0.361 - 150.3 1 2 1 -0.0002 11 0 0 0 5.92E+08 4.24E+08 - - - 4.2722 1 221125_WJC_METTL3_EV_vs_WT_F06.09687.09687.3 8.35E-07 16/52 K.AVTEQGAELSNEER[166.11].N "sp|P27348|1433T_HUMAN,tr|E9PG15|E9PG15_HUMAN" 2 1541.7197 1.13 79634 9687 3 1541.718781 514.9138 14-3-3 protein theta OS=Homo sapiens OX=9606 GN=YWHAQ PE=1 SV=1 4.09 1984.3 - 2.82E+06 - - - -0.5961 - 2.942 0.54 - 402.4 1 2 0 -0.0009 14 0 0 0 3.42E+07 3.03E+07 - - - 7.4279 0.9994 221125_WJC_METTL3_EV_vs_WT_F06.09688.09688.2 0.17 14-Oct K.QEIAEINR.M "sp|P48668|K2C6C_HUMAN,sp|P04259|K2C6B_HUMAN,sp|P02538|K2C6A_HUMAN" 3 971.5036 999 79635 9688 2 971.503836 486.7591 "Keratin, type II cytoskeletal 6C OS=Homo sapiens OX=9606 GN=KRT6C PE=1 SV=3" 4.53 1984.4 - 2.89E+06 - - - 0.2337 - 2.037 0.229 - 472.3 1 2 0 0.0002 8 0 0 0 3.41E+07 0.00E+00 - - - 2.8781 0.9996 221125_WJC_METTL3_EV_vs_WT_F06.09689.09689.3 0.00373 Sep-36 K.LDFNTDEEK[136.11]K[136.11].M sp|P42285|MTREX_HUMAN 1 1253.611 1 79636 9689 3 1253.610612 418.8776 Exosome RNA helicase MTR4 OS=Homo sapiens OX=9606 GN=MTREX PE=1 SV=3 4.32 1984.5 - 1.65E+06 - - - -0.347 - 1.624 0.369 - 111.9 1 2 0 -0.0004 10 0 0 0 1.58E+07 1.57E+07 - - - 4.07 0.9988 221125_WJC_METTL3_EV_vs_WT_F06.09690.09690.2 1.37E-06 13/20 K.TK[136.11]EGVLYVGSK[136.11].T "sp|Q16143|SYUB_HUMAN,sp|P37840|SYUA_HUMAN,tr|A0A669KB41|A0A669KB41_HUMAN,tr|D6RA31|D6RA31_HUMAN,tr|A0A669KBH5|A0A669KBH5_HUMAN,tr|E7EPV7|E7EPV7_HUMAN" 6 1195.6783 1.45 79637 9690 2 1195.678952 598.8464 Beta-synuclein OS=Homo sapiens OX=9606 GN=SNCB PE=1 SV=1 8.17 1984.6 - 1.06E+06 - - - 0.5127 - 2.249 0.549 - 354.7 1 2 1 0.0006 11 0 0 0 1.97E+08 1.36E+08 - - - 5.2883 0.9985 221125_WJC_METTL3_EV_vs_WT_F06.09691.09691.3 6.71E-07 17/44 R.PNRPGVYTNLC[160.03]K.F sp|Q9Y337|KLK5_HUMAN 1 1417.7136 2.98 79638 9691 3 1417.71395 473.5785 Kallikrein-5 OS=Homo sapiens OX=9606 GN=KLK5 PE=1 SV=3 9.37 1984.7 - 1.02E+06 - - - 0.2335 - 2.981 0.543 - 408 1 1 0 0.0003 12 0 0 0 1.16E+07 3.88E+06 - - - 7.6214 0.9783 221125_WJC_METTL3_EV_vs_WT_F06.09692.09692.2 8.80E-06 16-Dec L.EAHIDSANK[136.11].N sp|P35579|MYH9_HUMAN 1 991.4814 1.22 79639 9692 2 991.483153 496.748 Myosin-9 OS=Homo sapiens OX=9606 GN=MYH9 PE=1 SV=4 5.32 1984.8 - 987985 - - - 1.7449 - 1.964 0.431 - 426.3 1 1 0 0.0017 9 0 0 0 1.16E+07 9.51E+06 - - - 4.1766 0.9997 221125_WJC_METTL3_EV_vs_WT_F06.09698.09698.3 0.00239 13/44 K.VEGQPLHTELNR.A sp|Q15699|ALX1_HUMAN 1 1391.7157 1.65 79643 9698 3 1391.71577 464.9125 ALX homeobox protein 1 OS=Homo sapiens OX=9606 GN=ALX1 PE=1 SV=2 5.4 1985.6 - 3.72E+06 - - - 0.0309 - 2.243 0.321 - 338.4 1 2 0 0 12 0 0 0 3.66E+07 2.22E+07 - - - 4.358 0.9999 221125_WJC_METTL3_EV_vs_WT_F06.09699.09699.3 0.0568 15/44 K.AAYEAELGDARK.T "sp|P02545|LMNA_HUMAN,tr|A0A6Q8PF80|A0A6Q8PF80_HUMAN,tr|A0A804HL68|A0A804HL68_HUMAN,tr|A0A6Q8PFM1|A0A6Q8PFM1_HUMAN,tr|A0A6Q8PF59|A0A6Q8PF59_HUMAN,tr|A0A6Q8PFJ0|A0A6Q8PFJ0_HUMAN,tr|A0A6Q8PHQ9|A0A6Q8PHQ9_HUMAN,tr|A0A6Q8PGH0|A0A6Q8PGH0_HUMAN,tr|Q3BDU5|Q3BDU5_HUMAN" 9 1292.6361 2.01 79644 9699 3 1292.635507 431.886 Prelamin-A\C OS=Homo sapiens OX=9606 GN=LMNA PE=1 SV=1 4.68 1985.7 - 2.08E+06 - - - -0.4433 - 2.482 0.37 - 268.6 1 2 0 -0.0006 12 0 0 0 2.48E+07 1.24E+07 - - - 5.1848 0.8075 221125_WJC_METTL3_EV_vs_WT_F06.09700.09700.3 1.23 Jul-44 K.VSYAR[166.11]PSSEVIK[136.11].D "sp|Q15717|ELAV1_HUMAN,tr|M0R055|M0R055_HUMAN,tr|M0QZR9|M0QZR9_HUMAN" 3 1352.7419 1.35 79645 9700 3 1352.74225 451.9212 ELAV-like protein 1 OS=Homo sapiens OX=9606 GN=ELAVL1 PE=1 SV=2 8.56 1985.7 - 2.29E+06 - - - 0.2698 - 1.353 0.059 - 85.2 1 2 0 0.0004 12 0 0 0 1.60E+08 1.19E+08 - - - 0.0357 0.9884 221125_WJC_METTL3_EV_vs_WT_F06.09701.09701.3 0.342 Sep-44 K.VSYARPSSEVIK.D "sp|Q15717|ELAV1_HUMAN,tr|M0R055|M0R055_HUMAN,tr|M0QZR9|M0QZR9_HUMAN" 3 1334.7194 1.35 79646 9701 3 1334.71929 445.9137 ELAV-like protein 1 OS=Homo sapiens OX=9606 GN=ELAVL1 PE=1 SV=2 8.56 1985.8 - 1.94E+06 - - - -0.0937 - 1.819 0.136 - 142.7 1 2 0 -0.0001 12 0 0 0 1.60E+08 1.19E+08 - - - 1.7146 0.9999 221125_WJC_METTL3_EV_vs_WT_F06.09702.09702.3 0.00159 Oct-40 K.GDEC[160.03]ELLGHSK.N sp|P49411|EFTU_HUMAN 1 1243.5503 0.37 79647 9702 3 1243.547651 415.524 "Elongation factor Tu, mitochondrial OS=Homo sapiens OX=9606 GN=TUFM PE=1 SV=2" 4.65 1985.8 - 1.23E+06 - - - -2.131 - 1.854 0.465 - 127.7 1 2 0 -0.0027 11 0 0 0 1.79E+07 4.85E+07 - - - 5.4773 0.9999 221125_WJC_METTL3_EV_vs_WT_F06.09704.09704.3 4.80E-06 Dec-44 K.EAPPMEK[136.11]PEVVK[136.11].T "sp|P62841|RS15_HUMAN,tr|K7EJ78|K7EJ78_HUMAN,tr|K7EM56|K7EM56_HUMAN,tr|A0A0B4J2B4|A0A0B4J2B4_HUMAN,tr|S4R456|S4R456_HUMAN,tr|K7ELC2|K7ELC2_HUMAN,tr|K7EQJ5|K7EQJ5_HUMAN,tr|S4R417|S4R417_HUMAN" 8 1368.7294 1.32 79649 9704 3 1368.726427 457.2504 40S ribosomal protein S15 OS=Homo sapiens OX=9606 GN=RPS15 PE=1 SV=2 4.79 1986 - 786698 - - - -2.1633 - 2.492 0.503 - 153.8 1 2 0 -0.003 12 0 0 0 3.38E+08 2.56E+08 - - - 6.6781 0.9394 221125_WJC_METTL3_EV_vs_WT_F06.09705.09705.2 0.000983 16-Oct L.EAHIDSANK.N sp|P35579|MYH9_HUMAN 1 983.4672 1.32 79650 9705 2 983.466151 492.7409 Myosin-9 OS=Homo sapiens OX=9606 GN=MYH9 PE=1 SV=4 5.32 1986.1 - 778663 - - - -1.09 - 1.932 0.211 - 337.4 1 1 0 -0.0011 9 0 0 0 1.31E+07 9.96E+06 - - - 2.5043 0.9968 221125_WJC_METTL3_EV_vs_WT_F06.09706.09706.2 0.000705 20-Nov K.ALQQEQEIEQR.L "sp|Q86YP4|P66A_HUMAN,sp|Q8WXI9|P66B_HUMAN,tr|A0A0U1RRM1|A0A0U1RRM1_HUMAN,tr|A0A0U1RR30|A0A0U1RR30_HUMAN" 4 1370.679 1.58 79651 9706 2 1370.684305 686.3468 Transcriptional repressor p66-alpha OS=Homo sapiens OX=9606 GN=GATAD2A PE=1 SV=1 4.25 1986.2 - 352151 - - - 3.8652 - 2.355 0.27 - 604.9 1 2 0 0.0053 11 0 0 0 4.11E+07 2.60E+07 - - - 3.3507 1 221125_WJC_METTL3_EV_vs_WT_F06.09711.09711.2 8.00E-09 28-Oct K.IIDSDEGPEC[160.03]HPPVK.V sp|Q08554|DSC1_HUMAN 1 1691.7825 999 79656 9711 2 1691.783652 846.8985 Desmocollin-1 OS=Homo sapiens OX=9606 GN=DSC1 PE=1 SV=2 4.31 1986.9 - 175079 - - - 0.6892 - 2.172 0.647 - 244.8 1 2 0 0.0012 15 0 0 0 4.09E+06 0.00E+00 - - - 5.7263 0.9998 221125_WJC_METTL3_EV_vs_WT_F06.09716.09716.2 4.38E-05 18-Sep R.NGVMPSHFSR.G "sp|P39019|RS19_HUMAN,tr|A0A075B6E2|A0A075B6E2_HUMAN" 2 1130.5291 1.11 79659 9716 2 1130.528004 566.2718 40S ribosomal protein S19 OS=Homo sapiens OX=9606 GN=RPS19 PE=1 SV=2 9.76 1987.4 - 2.60E+06 - - - -0.9801 - 1.844 0.464 - 197.2 1 2 0 -0.0011 10 0 0 0 3.00E+08 2.69E+08 - - - 4.1759 0.9995 221125_WJC_METTL3_EV_vs_WT_F06.09720.09720.2 0.0767 15/20 K.ALQQEQEIEQR[166.11].L "sp|Q86YP4|P66A_HUMAN,sp|Q8WXI9|P66B_HUMAN,tr|A0A0U1RRM1|A0A0U1RRM1_HUMAN,tr|A0A0U1RR30|A0A0U1RR30_HUMAN" 4 1380.6873 1.6 79663 9720 2 1380.686142 691.3509 Transcriptional repressor p66-alpha OS=Homo sapiens OX=9606 GN=GATAD2A PE=1 SV=1 4.25 1987.8 - 834248 - - - -0.8221 - 2.316 0.25 - 1401.8 1 2 0 -0.0011 11 0 0 0 4.11E+07 2.56E+07 - - - 3.1591 0.9999 221125_WJC_METTL3_EV_vs_WT_F06.09723.09723.2 8.71E-07 20-Sep K.GDEC[160.03]ELLGHSK.N sp|P49411|EFTU_HUMAN 1 1243.5503 2.34 79666 9723 2 1243.550437 622.7824 "Elongation factor Tu, mitochondrial OS=Homo sapiens OX=9606 GN=TUFM PE=1 SV=2" 4.65 1988.2 - 466500 - - - 0.1094 - 2.07 0.479 - 393.4 1 2 0 0.0001 11 0 0 0 4.43E+06 1.90E+06 - - - 4.547 0.971 221125_WJC_METTL3_EV_vs_WT_F06.09724.09724.2 0.0465 20-Sep V.SYARPSSEVIK.D "sp|Q15717|ELAV1_HUMAN,tr|M0R055|M0R055_HUMAN,tr|M0QZR9|M0QZR9_HUMAN" 3 1235.651 1.69 79667 9724 2 1235.651847 618.8328 ELAV-like protein 1 OS=Homo sapiens OX=9606 GN=ELAVL1 PE=1 SV=2 8.31 1988.3 - 456869 - - - 0.6847 - 2.086 0.291 - 291.6 1 1 0 0.0008 11 0 0 0 1.16E+07 6.87E+06 - - - 3.1791 0.9996 221125_WJC_METTL3_EV_vs_WT_F06.09726.09726.2 0.0143 22-Nov K.VEGQPLHTELNR.A sp|Q15699|ALX1_HUMAN 1 1391.7157 2.28 79669 9726 2 1391.716194 696.8651 ALX homeobox protein 1 OS=Homo sapiens OX=9606 GN=ALX1 PE=1 SV=2 5.4 1988.6 - 392326 - - - 0.3356 - 1.995 0.335 - 305.6 1 2 0 0.0005 12 0 0 0 4.00E+06 1.76E+06 - - - 3.3324 0.9995 221125_WJC_METTL3_EV_vs_WT_F06.09728.09728.2 0.000382 20-Nov R.DTDSSVASEVR[166.11].S "sp|Q86X29|LSR_HUMAN,tr|S4R3V8|S4R3V8_HUMAN" 2 1174.5341 4 79671 9728 2 1174.535254 588.2743 Lipolysis-stimulated lipoprotein receptor OS=Homo sapiens OX=9606 GN=LSR PE=1 SV=4 4.03 1988.8 - 211569 - - - 0.9561 - 2.413 0.267 - 503.6 1 2 0 0.0011 11 0 0 0 1.48E+07 3.70E+06 - - - 3.3957 0.9999 221125_WJC_METTL3_EV_vs_WT_F06.09729.09729.2 6.49E-08 14/26 K.ALYEQNQSDVNEAK[136.11].S sp|Q14691|PSF1_HUMAN 1 1615.7569 0.35 79672 9729 2 1615.756329 808.8857 DNA replication complex GINS protein PSF1 OS=Homo sapiens OX=9606 GN=GINS1 PE=1 SV=1 4.14 1989 - 206772 - - - -0.372 - 3.036 0.503 - 541.8 1 2 0 -0.0006 14 0 0 0 5.72E+05 1.62E+06 - - - 5.5428 0.9999 221125_WJC_METTL3_EV_vs_WT_F06.09733.09733.2 2.10E-07 14/18 K.K[136.11]EDALLYQSK[136.11].G "sp|P50402|EMD_HUMAN,tr|A0A804HLA2|A0A804HLA2_HUMAN,tr|A0A804HIV7|A0A804HIV7_HUMAN,tr|Q5HY57|Q5HY57_HUMAN" 4 1209.6576 1.25 79674 9733 2 1209.657496 605.8361 Emerin OS=Homo sapiens OX=9606 GN=EMD PE=1 SV=1 6.07 1989.4 - 2.04E+06 - - - -0.0885 - 3.056 0.471 - 603.1 1 2 0 -0.0001 10 0 0 0 2.64E+07 2.11E+07 - - - 5.638 0.9999 221125_WJC_METTL3_EV_vs_WT_F06.09734.09734.3 1.74E-05 Dec-40 R.IYNDDKNTYIR.Y sp|O75533|SF3B1_HUMAN 1 1413.6888 0.83 79675 9734 3 1413.688741 472.2369 Splicing factor 3B subunit 1 OS=Homo sapiens OX=9606 GN=SF3B1 PE=1 SV=3 5.96 1989.5 - 2.04E+06 - - - -0.0729 - 2.397 0.539 - 204.8 1 2 1 -0.0001 11 0 0 0 4.38E+07 5.25E+07 - - - 7.0328 0.9995 221125_WJC_METTL3_EV_vs_WT_F06.09735.09735.3 0.0025 Nov-44 K.VEGQPLHTELNR[166.11].A sp|Q15699|ALX1_HUMAN 1 1401.724 1.95 79676 9735 3 1401.726934 468.2486 ALX homeobox protein 1 OS=Homo sapiens OX=9606 GN=ALX1 PE=1 SV=2 5.4 1989.5 - 1.47E+06 - - - 2.0953 - 2.2 0.329 - 170.2 1 2 0 0.0029 12 0 0 0 4.35E+07 2.24E+07 - - - 4.3927 0.9994 221125_WJC_METTL3_EV_vs_WT_F06.09737.09737.2 0.00253 22-Dec K.VSYAR[166.11]PSSEVIK[136.11].D "sp|Q15717|ELAV1_HUMAN,tr|M0R055|M0R055_HUMAN,tr|M0QZR9|M0QZR9_HUMAN" 3 1352.7419 1.33 79678 9737 2 1352.7422 677.3782 ELAV-like protein 1 OS=Homo sapiens OX=9606 GN=ELAVL1 PE=1 SV=2 8.56 1989.8 - 1.04E+06 - - - 0.2329 - 2.239 0.239 - 396.5 1 2 0 0.0003 12 0 0 0 1.74E+07 1.30E+07 - - - 2.927 1 221125_WJC_METTL3_EV_vs_WT_F06.09738.09738.2 3.89E-08 14/24 R.QLSMSSADSADAK.R sp|Q5JSZ5|PRC2B_HUMAN 1 1309.582 0.86 79679 9738 2 1309.580791 655.7983 Protein PRRC2B OS=Homo sapiens OX=9606 GN=PRRC2B PE=1 SV=2 4.21 1989.9 - 772720 - - - -0.9194 - 2.743 0.631 - 839.6 1 2 0 -0.0012 13 0 0 0 8.19E+06 9.50E+06 - - - 6.2909 0.9991 221125_WJC_METTL3_EV_vs_WT_F06.09745.09745.2 2.27E-07 28-Oct R.LGAPQQPGPGPPPSR.R sp|Q96CX2|KCD12_HUMAN 1 1454.763 1.29 79686 9745 2 1454.757754 728.3888 BTB\POZ domain-containing protein KCTD12 OS=Homo sapiens OX=9606 GN=KCTD12 PE=1 SV=1 9.75 1990.7 - 145217 - - - -3.6143 - 2.154 0.518 - 170.9 1 2 0 -0.0053 15 0 0 0 6.33E+06 4.92E+06 - - - 4.7518 0.9999 221125_WJC_METTL3_EV_vs_WT_F06.09749.09749.3 2.15E-06 13/40 R.IYNDDK[136.11]NTYIR[166.11].Y sp|O75533|SF3B1_HUMAN 1 1431.7113 1.29 79688 9749 3 1431.710203 478.2444 Splicing factor 3B subunit 1 OS=Homo sapiens OX=9606 GN=SF3B1 PE=1 SV=3 5.96 1991.2 - 3.55E+06 - - - -0.776 - 2.548 0.54 - 235.4 1 2 1 -0.0011 11 0 0 0 4.13E+07 3.21E+07 - - - 7.2172 0.9999 221125_WJC_METTL3_EV_vs_WT_F06.09750.09750.3 0.000248 Nov-40 R.NTFDHPYPTTK.L sp|P61962|DCAF7_HUMAN 1 1319.6146 1.31 79689 9750 3 1319.615344 440.8788 DDB1- and CUL4-associated factor 7 OS=Homo sapiens OX=9606 GN=DCAF7 PE=1 SV=1 6.74 1991.2 - 2.39E+06 - - - 0.5517 - 1.957 0.393 - 155.4 1 2 0 0.0007 11 0 0 0 3.42E+08 2.61E+08 - - - 4.8287 0.9999 221125_WJC_METTL3_EV_vs_WT_F06.09751.09751.3 0.000153 Dec-40 R.HVGSNLC[160.03]LDSR[166.11].T sp|Q10471|GALT2_HUMAN 1 1266.6014 11.03 79690 9751 3 1266.601419 423.2078 Polypeptide N-acetylgalactosaminyltransferase 2 OS=Homo sapiens OX=9606 GN=GALNT2 PE=1 SV=1 6.74 1991.3 - 2.77E+06 - - - -0.0158 - 2.051 0.418 - 259 1 2 0 0 11 0 0 0 8.77E+08 7.95E+07 - - - 5.2409 1 221125_WJC_METTL3_EV_vs_WT_F06.09752.09752.3 3.76E-06 Dec-40 R.NTFDHPYPTTK[136.11].L sp|P61962|DCAF7_HUMAN 1 1327.6288 1.32 79691 9752 3 1327.629317 443.5502 DDB1- and CUL4-associated factor 7 OS=Homo sapiens OX=9606 GN=DCAF7 PE=1 SV=1 6.74 1991.3 - 2.65E+06 - - - 0.3774 - 2.36 0.489 - 260.1 1 2 0 0.0005 11 0 0 0 3.42E+08 2.58E+08 - - - 6.431 0.9995 221125_WJC_METTL3_EV_vs_WT_F06.09753.09753.2 0.0145 22-Oct K.VSYARPSSEVIK.D "sp|Q15717|ELAV1_HUMAN,tr|M0R055|M0R055_HUMAN,tr|M0QZR9|M0QZR9_HUMAN" 3 1334.7194 1.33 79692 9753 2 1334.720106 668.367 ELAV-like protein 1 OS=Homo sapiens OX=9606 GN=ELAVL1 PE=1 SV=2 8.56 1991.4 - 1.68E+06 - - - 0.5177 - 2.065 0.286 - 239.9 1 2 0 0.0007 12 0 0 0 1.74E+07 1.30E+07 - - - 3.0611 0.9189 221125_WJC_METTL3_EV_vs_WT_F06.09754.09754.2 0.000917 16-Jun N.GVMPSHFSR.G "sp|P39019|RS19_HUMAN,tr|A0A075B6E2|A0A075B6E2_HUMAN" 2 1016.4862 1.12 79693 9754 2 1016.485645 509.2504 40S ribosomal protein S19 OS=Homo sapiens OX=9606 GN=RPS19 PE=1 SV=2 9.76 1991.5 - 1.58E+06 - - - -0.5312 - 1.401 0.278 - 120.9 1 1 0 -0.0005 9 0 0 0 4.78E+07 4.29E+07 - - - 2.0696 0.9877 221125_WJC_METTL3_EV_vs_WT_F06.09757.09757.3 0.351 Aug-40 K.ALQQEQEIEQR.L "sp|Q86YP4|P66A_HUMAN,sp|Q8WXI9|P66B_HUMAN,tr|A0A0U1RRM1|A0A0U1RRM1_HUMAN,tr|A0A0U1RR30|A0A0U1RR30_HUMAN" 4 1370.679 1.65 79696 9757 3 1370.677456 457.9003 Transcriptional repressor p66-alpha OS=Homo sapiens OX=9606 GN=GATAD2A PE=1 SV=1 4.25 1991.7 - 1.33E+06 - - - -1.1316 - 1.787 0.137 - 113.7 1 2 0 -0.0016 11 0 0 0 1.03E+07 6.27E+06 - - - 1.7162 0.999 221125_WJC_METTL3_EV_vs_WT_F06.09758.09758.3 0.00113 Oct-36 K.LK[136.11]LTNNISDK[136.11].H "sp|Q13207|TBX2_HUMAN,sp|O15119|TBX3_HUMAN" 2 1160.6736 0.6 79697 9758 3 1160.674853 387.8985 T-box transcription factor TBX2 OS=Homo sapiens OX=9606 GN=TBX2 PE=1 SV=3 8.59 1991.8 - 1.24E+06 - - - 1.0899 - 1.961 0.37 - 93.8 1 2 1 0.0013 10 0 0 0 5.52E+06 9.26E+06 - - - 4.6316 0.9935 221125_WJC_METTL3_EV_vs_WT_F06.09761.09761.2 0.0641 18-Nov K.LK[136.11]LTNNISDK[136.11].H "sp|Q13207|TBX2_HUMAN,sp|O15119|TBX3_HUMAN" 2 1160.6736 0.57 79700 9761 2 1160.671913 581.3441 T-box transcription factor TBX2 OS=Homo sapiens OX=9606 GN=TBX2 PE=1 SV=3 8.59 1992.1 - 637881 - - - -1.4431 - 1.965 0.319 - 253.8 1 2 1 -0.0017 10 0 0 0 3.40E+06 6.01E+06 - - - 3.2821 0.9996 221125_WJC_METTL3_EV_vs_WT_F06.09762.09762.2 0.0796 18-Nov K.KQEVQTAILR.V "sp|Q96KQ4|ASPP1_HUMAN,tr|A0A3B3ISJ2|A0A3B3ISJ2_HUMAN" 2 1184.6877 2.19 79701 9762 2 1184.689733 593.3511 Apoptosis-stimulating of p53 protein 1 OS=Homo sapiens OX=9606 GN=PPP1R13B PE=1 SV=3 8.75 1992.3 - 696836 - - - 1.6983 - 2.114 0.378 - 378.8 1 2 0 0.002 10 0 0 0 3.70E+06 1.69E+06 - - - 3.9218 0.9821 221125_WJC_METTL3_EV_vs_WT_F06.09763.09763.3 0.378 Sep-48 K.NLAANR[166.11]PPNTYVK[136.11].L sp|Q8NB59|SYT14_HUMAN 1 1474.8011 1.67 79702 9763 3 1474.801902 492.6077 Synaptotagmin-14 OS=Homo sapiens OX=9606 GN=SYT14 PE=1 SV=2 9.99 1992.4 - 596350 - - - 0.5221 - 1.664 0.138 - 99.6 1 2 0 0.0008 13 0 0 0 9.12E+06 5.46E+06 - - - 1.459 1 221125_WJC_METTL3_EV_vs_WT_F06.09765.09765.2 2.59E-06 20-Dec R.GC[160.03]AFC[160.03]GGLGHR[166.11].L sp|Q9UJV9|DDX41_HUMAN 1 1200.5156 0.71 79704 9765 2 1200.517665 601.2651 Probable ATP-dependent RNA helicase DDX41 OS=Homo sapiens OX=9606 GN=DDX41 PE=1 SV=2 8.08 1992.7 - 999412 - - - 1.7193 - 2.4 0.606 - 494.6 1 2 0 0.0021 11 0 0 0 4.41E+06 6.22E+06 - - - 5.8846 0.9999 221125_WJC_METTL3_EV_vs_WT_F06.09769.09769.2 4.67E-07 13/20 R.NTFDHPYPTTK[136.11].L sp|P61962|DCAF7_HUMAN 1 1327.6288 1.41 79706 9769 2 1327.628549 664.8217 DDB1- and CUL4-associated factor 7 OS=Homo sapiens OX=9606 GN=DCAF7 PE=1 SV=1 6.74 1993.2 - 959266 - - - -0.2011 - 2.232 0.568 - 520.9 1 2 0 -0.0003 11 0 0 0 5.67E+07 4.01E+07 - - - 5.4082 1 221125_WJC_METTL3_EV_vs_WT_F06.09773.09773.2 2.26E-07 13/24 K.EASGETTGVDITK.L "sp|O75152|ZC11A_HUMAN,tr|E9PQ61|E9PQ61_HUMAN" 2 1306.6252 0.9 79710 9773 2 1306.623826 654.3199 Zinc finger CCCH domain-containing protein 11A OS=Homo sapiens OX=9606 GN=ZC3H11A PE=1 SV=3 4.14 1993.5 - 927379 - - - -1.0822 - 2.806 0.558 - 772.3 1 2 0 -0.0014 13 0 0 0 2.26E+07 2.53E+07 - - - 5.81 0.9991 221125_WJC_METTL3_EV_vs_WT_F06.09774.09774.2 8.39E-05 14-Sep R.K[136.11]YGLNMC[160.03]R[166.11].Q "sp|P62273|RS29_HUMAN,tr|A0A2R8Y6P7|A0A2R8Y6P7_HUMAN,tr|A0A2R8Y851|A0A2R8Y851_HUMAN,tr|A0A087WTT6|A0A087WTT6_HUMAN" 4 1058.512 1.04 79711 9774 2 1058.514954 530.2633 40S ribosomal protein S29 OS=Homo sapiens OX=9606 GN=RPS29 PE=1 SV=2 9.31 1993.6 - 824176 - - - 2.7661 - 1.925 0.391 - 295.3 1 2 0 0.0029 8 0 0 0 7.22E+07 6.96E+07 - - - 3.9032 0.9817 221125_WJC_METTL3_EV_vs_WT_F06.09776.09776.2 0.124 20-Aug R.VSPPPAPSPPK.A "sp|O14654|IRS4_HUMAN,tr|A0A804CF45|A0A804CF45_HUMAN" 2 1072.5917 1.55 79713 9776 2 1072.590021 537.3031 Insulin receptor substrate 4 OS=Homo sapiens OX=9606 GN=IRS4 PE=1 SV=1 8.72 1993.8 - 560032 - - - -1.5616 - 1.526 0.065 - 169.3 2 2 0 -0.0017 11 0 0 0 1.20E+07 7.73E+06 - - - 0.5295 0.9788 221125_WJC_METTL3_EV_vs_WT_F06.09777.09777.3 0.149 Aug-40 K.FR[166.11]PDMEEEEAK[136.11].N sp|Q99436|PSB7_HUMAN 1 1397.6252 0.79 79714 9777 3 1397.625299 466.8823 Proteasome subunit beta type-7 OS=Homo sapiens OX=9606 GN=PSMB7 PE=1 SV=1 4.25 1993.9 - 516471 - - - 0.0701 - 1.563 0.139 - 91 1 2 0 0.0001 11 0 0 0 1.07E+07 1.35E+07 - - - 1.3584 0.9688 221125_WJC_METTL3_EV_vs_WT_F06.09778.09778.2 3.32 16-Jul K.QDSGHLDLR[166.11].N "sp|Q86U44|MTA70_HUMAN,tr|B4E349|B4E349_HUMAN,tr|F5H6D8|F5H6D8_HUMAN,tr|B4DTN4|B4DTN4_HUMAN" 4 1049.5129 0.001 79715 9778 2 1049.51227 525.7637 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 5.21 1994.1 - 482748 - - - -0.6393 - 1.096 0.081 - 162.6 1 2 0 -0.0007 9 0 0 0 0.00E+00 4.03E+06 - - - -0.0957 0.9917 221125_WJC_METTL3_EV_vs_WT_F06.09779.09779.2 2.16E-05 20-Nov R.IYNDDKNTYIR.Y sp|O75533|SF3B1_HUMAN 1 1413.6888 2.86 79716 9779 2 1413.694384 707.8517 Splicing factor 3B subunit 1 OS=Homo sapiens OX=9606 GN=SF3B1 PE=1 SV=3 5.96 1994.2 - 439179 - - - 3.9188 - 2.444 0.57 - 459 1 2 1 0.0055 11 0 0 0 3.02E+06 1.06E+06 - - - 5.6668 0.999 221125_WJC_METTL3_EV_vs_WT_F06.09783.09783.2 7.69E-07 13/26 R.GNLGAGNGNLQGPR.H "sp|P43243|MATR3_HUMAN,tr|D6RE02|D6RE02_HUMAN,tr|B3KM87|B3KM87_HUMAN,tr|A8MXP9|A8MXP9_HUMAN,tr|D6RAY2|D6RAY2_HUMAN,tr|D6R991|D6R991_HUMAN,tr|A0A0R4J2E8|A0A0R4J2E8_HUMAN,tr|D6RAM9|D6RAM9_HUMAN,tr|D6RIA2|D6RIA2_HUMAN,tr|H0Y8T4|H0Y8T4_HUMAN,tr|D6REM6|D6REM6_HUMAN,tr|D6RBI2|D6RBI2_HUMAN" 12 1323.6644 1.38 79719 9783 2 1323.669751 662.8395 Matrin-3 OS=Homo sapiens OX=9606 GN=MATR3 PE=1 SV=2 9.75 1994.7 - 671385 - - - 4.0728 - 2.578 0.533 - 558.3 1 2 0 0.0054 14 0 0 0 1.02E+10 7.36E+09 - - - 5.3525 0.8027 221125_WJC_METTL3_EV_vs_WT_F06.09784.09784.2 0.0409 16-Aug N.GVMPSHFSR[166.11].G "sp|P39019|RS19_HUMAN,tr|A0A075B6E2|A0A075B6E2_HUMAN" 2 1026.4945 1.15 79720 9784 2 1026.497536 514.2545 40S ribosomal protein S19 OS=Homo sapiens OX=9606 GN=RPS19 PE=1 SV=2 9.76 1994.7 - 2.85E+06 - - - 3.0015 - 1.54 0.296 - 211.6 1 1 0 0.0031 9 0 0 0 4.72E+07 4.10E+07 - - - 2.4755 1 221125_WJC_METTL3_EV_vs_WT_F06.09785.09785.2 1.59E-06 13/20 R.NTFDHPYPTTK.L sp|P61962|DCAF7_HUMAN 1 1319.6146 1.37 79721 9785 2 1319.613705 660.8146 DDB1- and CUL4-associated factor 7 OS=Homo sapiens OX=9606 GN=DCAF7 PE=1 SV=1 6.74 1994.8 - 1.82E+06 - - - -0.6904 - 2.578 0.613 - 450 1 2 0 -0.0009 11 0 0 0 5.67E+07 4.13E+07 - - - 6.1302 0.9999 221125_WJC_METTL3_EV_vs_WT_F06.09786.09786.2 8.94E-06 15/26 R.LSSEMNTSTVNSAR[166.11].E "sp|P20700|LMNB1_HUMAN,tr|E9PBF6|E9PBF6_HUMAN,tr|A0A0D9SFE5|A0A0D9SFE5_HUMAN" 3 1505.7019 1.12 79722 9786 2 1505.701611 753.8582 Lamin-B1 OS=Homo sapiens OX=9606 GN=LMNB1 PE=1 SV=2 6 1994.9 - 879007 - - - -0.2192 - 3.253 0.453 - 946.2 1 2 0 -0.0003 14 0 0 0 7.48E+07 6.71E+07 - - - 5.3468 1 221125_WJC_METTL3_EV_vs_WT_F06.09787.09787.2 6.62E-09 16/26 R.LSSEMNTSTVNSAR.E "sp|P20700|LMNB1_HUMAN,tr|E9PBF6|E9PBF6_HUMAN,tr|A0A0D9SFE5|A0A0D9SFE5_HUMAN" 3 1495.6937 1.12 79723 9787 2 1495.689358 748.8541 Lamin-B1 OS=Homo sapiens OX=9606 GN=LMNB1 PE=1 SV=2 6 1995.1 - 842807 - - - -2.8836 - 3.103 0.652 - 1077.1 1 2 0 -0.0043 14 0 0 0 7.48E+07 6.71E+07 - - - 6.6969 0.9998 221125_WJC_METTL3_EV_vs_WT_F06.09794.09794.2 0.000572 14-Sep R.KYGLNMC[160.03]R.Q "sp|P62273|RS29_HUMAN,tr|A0A2R8Y6P7|A0A2R8Y6P7_HUMAN,tr|A0A2R8Y851|A0A2R8Y851_HUMAN,tr|A0A087WTT6|A0A087WTT6_HUMAN" 4 1040.4896 1.04 79728 9794 2 1040.489005 521.2521 40S ribosomal protein S29 OS=Homo sapiens OX=9606 GN=RPS29 PE=1 SV=2 9.31 1996 - 4.01E+06 - - - -0.5296 - 1.821 0.439 - 318.6 1 2 0 -0.0006 8 0 0 0 7.22E+07 6.96E+07 - - - 4.091 0.9473 221125_WJC_METTL3_EV_vs_WT_F06.09796.09796.2 0.0177 14-Jul G.VMPSHFSR.G "sp|P39019|RS19_HUMAN,tr|A0A075B6E2|A0A075B6E2_HUMAN" 2 959.4647 1.01 79730 9796 2 959.463983 480.7396 40S ribosomal protein S19 OS=Homo sapiens OX=9606 GN=RPS19 PE=1 SV=2 9.73 1996.1 - 1.71E+06 - - - -0.7692 - 1.273 0.373 - 225.8 1 1 0 -0.0007 8 0 0 0 1.69E+07 1.67E+07 - - - 2.5237 0.9996 221125_WJC_METTL3_EV_vs_WT_F06.09797.09797.3 0.00298 Nov-32 R.R[166.11]LNHYVLYK[136.11].A sp|O43242|PSMD3_HUMAN 1 1222.6941 0.53 79731 9797 3 1222.694424 408.572 26S proteasome non-ATPase regulatory subunit 3 OS=Homo sapiens OX=9606 GN=PSMD3 PE=1 SV=2 9.7 1996.2 - 1.45E+06 - - - 0.2265 - 1.87 0.327 - 165.7 1 2 0 0.0003 9 0 0 0 1.13E+07 2.14E+07 - - - 4.0721 0.9997 221125_WJC_METTL3_EV_vs_WT_F06.09800.09800.2 0.00446 15/20 K.RAADEVLAEAK.K "sp|Q6P1J9|CDC73_HUMAN,tr|A0A2R8Y640|A0A2R8Y640_HUMAN,tr|A0A2R8YHB3|A0A2R8YHB3_HUMAN,tr|A0A1B0GUB2|A0A1B0GUB2_HUMAN,tr|A0A3B3IRP5|A0A3B3IRP5_HUMAN" 5 1171.6197 1.57 79734 9800 2 1171.619704 586.8171 Parafibromin OS=Homo sapiens OX=9606 GN=CDC73 PE=1 SV=1 4.68 1996.6 - 649778 - - - 0.0026 - 2.577 0.254 - 949.5 1 2 0 0 11 0 0 0 8.19E+06 5.20E+06 - - - 3.4779 0.9871 221125_WJC_METTL3_EV_vs_WT_F06.09801.09801.2 0.000275 16-Aug T.FDHPYPTTK.L sp|P61962|DCAF7_HUMAN 1 1104.524 2.42 79735 9801 2 1104.525397 553.2693 DDB1- and CUL4-associated factor 7 OS=Homo sapiens OX=9606 GN=DCAF7 PE=1 SV=1 6.74 1996.7 - 567517 - - - 1.2557 - 1.619 0.557 - 209.9 1 1 0 0.0014 9 0 0 0 8.07E+06 3.33E+06 - - - 4.5485 0.9958 221125_WJC_METTL3_EV_vs_WT_F06.09802.09802.2 0.00553 20-Aug R.VSPPPAPSPPK[136.11].A "sp|O14654|IRS4_HUMAN,tr|A0A804CF45|A0A804CF45_HUMAN" 2 1080.6059 1.42 79736 9802 2 1080.605822 541.3102 Insulin receptor substrate 4 OS=Homo sapiens OX=9606 GN=IRS4 PE=1 SV=1 8.72 1996.9 - 478315 - - - -0.0685 - 1.623 0.117 - 177.1 1 2 0 -0.0001 11 0 0 0 8.81E+06 6.19E+06 - - - 1.2152 0.9995 221125_WJC_METTL3_EV_vs_WT_F06.09804.09804.2 4.32E-05 13/28 R.LGAPQQPGPGPPPSR[166.11].R sp|Q96CX2|KCD12_HUMAN 1 1464.7713 1.35 79738 9804 2 1464.771201 733.3929 BTB\POZ domain-containing protein KCTD12 OS=Homo sapiens OX=9606 GN=KCTD12 PE=1 SV=1 9.75 1997.1 - 232201 - - - -0.0553 - 2.377 0.241 - 321.4 1 2 0 -0.0001 15 0 0 0 6.33E+06 4.71E+06 - - - 2.9497 0.8649 221125_WJC_METTL3_EV_vs_WT_F06.09811.09811.2 0.00779 14-Jul G.VMPSHFSR[166.11].G "sp|P39019|RS19_HUMAN,tr|A0A075B6E2|A0A075B6E2_HUMAN" 2 969.473 1.01 79743 9811 2 969.473445 485.7438 40S ribosomal protein S19 OS=Homo sapiens OX=9606 GN=RPS19 PE=1 SV=2 9.73 1997.7 - 1.69E+06 - - - 0.4683 - 1.303 0.245 - 215.9 1 1 0 0.0005 8 0 0 0 1.69E+07 1.67E+07 - - - 1.6487 0.999 221125_WJC_METTL3_EV_vs_WT_F06.09813.09813.3 0.0172 Nov-36 R.IGNSYFKEEK.Y sp|P31948|STIP1_HUMAN 1 1213.5979 0.82 79745 9813 3 1213.595932 405.5399 Stress-induced-phosphoprotein 1 OS=Homo sapiens OX=9606 GN=STIP1 PE=1 SV=1 6.14 1997.9 - 1.32E+06 - - - -1.6241 - 2.253 0.35 - 107.5 1 2 1 -0.002 10 0 0 0 1.29E+07 1.57E+07 - - - 4.8138 0.9999 221125_WJC_METTL3_EV_vs_WT_F06.09818.09818.2 1.15 20-Dec R.TENC[160.03]LSSC[160.03]VDR.F "sp|Q9Y5J9|TIM8B_HUMAN,tr|G3XAN8|G3XAN8_HUMAN" 2 1339.5496 2.21 79750 9818 2 1339.549614 670.7821 Mitochondrial import inner membrane translocase subunit Tim8 B OS=Homo sapiens OX=9606 GN=TIMM8B PE=1 SV=1 4.37 1998.5 - 669774 - - - -0.0269 - 2.489 0.514 - 580.3 1 2 0 0 11 0 0 0 7.39E+06 3.34E+06 - - - 5.3042 0.9998 221125_WJC_METTL3_EV_vs_WT_F06.09819.09819.2 0.000821 13/28 K.QGGGGGGGSVPGIER[166.11].M "sp|P52272|HNRPM_HUMAN,tr|M0R019|M0R019_HUMAN,tr|A0A087X0X3|A0A087X0X3_HUMAN,tr|M0R2T0|M0R2T0_HUMAN" 4 1293.6301 2.28 79751 9819 2 1293.632369 647.8223 Heterogeneous nuclear ribonucleoprotein M OS=Homo sapiens OX=9606 GN=HNRNPM PE=1 SV=3 6 1998.6 - 391426 - - - 1.7563 - 2.644 0.471 - 410.4 1 2 0 0.0023 15 0 0 0 1.91E+07 8.36E+06 - - - 4.9095 0.9994 221125_WJC_METTL3_EV_vs_WT_F06.09822.09822.3 0.00118 Oct-40 K.TKEGVLYVGSK.T "sp|Q16143|SYUB_HUMAN,sp|P37840|SYUA_HUMAN,tr|A0A669KB41|A0A669KB41_HUMAN,tr|D6RA31|D6RA31_HUMAN,tr|A0A669KBH5|A0A669KBH5_HUMAN,tr|E7EPV7|E7EPV7_HUMAN" 6 1179.6499 1.39 79753 9822 3 1179.649135 394.2239 Beta-synuclein OS=Homo sapiens OX=9606 GN=SNCB PE=1 SV=1 8.17 1999 - 2.63E+06 - - - -0.6816 - 1.73 0.437 - 142.4 1 2 1 -0.0008 11 0 0 0 5.91E+08 4.24E+08 - - - 4.969 0.9995 221125_WJC_METTL3_EV_vs_WT_F06.09826.09826.2 0.000121 16-Oct R.TSYEEFTHK[136.11].D sp|Q6P2Q9|PRP8_HUMAN 1 1148.523 0.01 79757 9826 2 1148.519926 575.2688 Pre-mRNA-processing-splicing factor 8 OS=Homo sapiens OX=9606 GN=PRPF8 PE=1 SV=2 5.37 1999.3 - 1.23E+06 - - - -2.6364 - 1.757 0.528 - 361.8 1 2 0 -0.003 9 0 0 0 1.08E+05 8.98E+06 - - - 4.5704 0.9999 221125_WJC_METTL3_EV_vs_WT_F06.09833.09833.2 2.04E-05 18-Jul R.NGVMPSHFSR[166.11].G "sp|P39019|RS19_HUMAN,tr|A0A075B6E2|A0A075B6E2_HUMAN" 2 1140.5374 1.11 79763 9833 2 1140.538375 571.276 40S ribosomal protein S19 OS=Homo sapiens OX=9606 GN=RPS19 PE=1 SV=2 9.76 2000.2 - 1.59E+07 - - - 0.8706 - 2.002 0.527 - 181.7 1 2 0 0.001 10 0 0 0 3.00E+08 2.70E+08 - - - 4.8707 0.9464 221125_WJC_METTL3_EV_vs_WT_F06.09834.09834.2 0.00675 12-Jun V.MPSHFSR.G "sp|P39019|RS19_HUMAN,tr|A0A075B6E2|A0A075B6E2_HUMAN" 2 860.3963 1.08 79764 9834 2 860.396249 431.2054 40S ribosomal protein S19 OS=Homo sapiens OX=9606 GN=RPS19 PE=1 SV=2 9.52 2000.2 - 6.08E+06 - - - -0.0674 - 1.305 0.343 - 169 1 1 0 -0.0001 7 0 0 0 9.44E+07 8.75E+07 - - - 2.4179 0.9399 221125_WJC_METTL3_EV_vs_WT_F06.09836.09836.2 0.00845 16-Sep K.K[136.11]QQISLATQ.M "sp|P48643|TCPE_HUMAN,tr|E9PCA1|E9PCA1_HUMAN,tr|B7ZAR1|B7ZAR1_HUMAN,tr|E7ENZ3|E7ENZ3_HUMAN" 4 1023.5804 0.61 79766 9836 2 1023.579916 512.7975 T-complex protein 1 subunit epsilon OS=Homo sapiens OX=9606 GN=CCT5 PE=1 SV=1 8.75 2000.3 - 3.20E+06 - - - -0.4816 - 1.804 0.215 - 304.7 1 1 0 -0.0005 9 0 0 0 1.65E+07 2.70E+07 - - - 2.3358 0.9998 221125_WJC_METTL3_EV_vs_WT_F06.09837.09837.3 0.0175 Oct-32 R.RLNHYVLYK.A sp|O43242|PSMD3_HUMAN 1 1204.6717 0.52 79767 9837 3 1204.670849 402.5645 26S proteasome non-ATPase regulatory subunit 3 OS=Homo sapiens OX=9606 GN=PSMD3 PE=1 SV=2 9.7 2000.4 - 1.59E+06 - - - -0.6873 - 2.176 0.334 - 157.7 1 2 0 -0.0008 9 0 0 0 1.11E+07 2.14E+07 - - - 4.6067 0.9987 221125_WJC_METTL3_EV_vs_WT_F06.09838.09838.2 0.000551 16-Aug R.NFVSHLNQR.H sp|Q8WVD3|RN138_HUMAN 1 1113.5679 1.32 79768 9838 2 1113.571566 557.7912 E3 ubiquitin-protein ligase RNF138 OS=Homo sapiens OX=9606 GN=RNF138 PE=1 SV=1 9.76 2000.5 - 1.45E+06 - - - 3.2562 - 1.684 0.45 - 289.2 1 2 0 0.0036 9 0 0 0 6.58E+07 5.01E+07 - - - 3.8713 0.9997 221125_WJC_METTL3_EV_vs_WT_F06.09839.09839.2 0.0385 15/28 R.FGQGGAGPVGGQGPR.G sp|P23246|SFPQ_HUMAN 1 1340.6585 0.82 79769 9839 2 1340.655283 671.3365 "Splicing factor, proline- and glutamine-rich OS=Homo sapiens OX=9606 GN=SFPQ PE=1 SV=2" 9.75 2000.6 - 929441 - - - -2.4339 - 2.922 0.495 - 831.4 1 2 0 -0.0033 15 0 0 0 1.20E+07 1.46E+07 - - - 5.3323 0.7684 221125_WJC_METTL3_EV_vs_WT_F06.09842.09842.2 0.000449 18-Nov N.TFDHPYPTTK[136.11].L sp|P61962|DCAF7_HUMAN 1 1213.5859 0.85 79772 9842 2 1213.590825 607.8002 DDB1- and CUL4-associated factor 7 OS=Homo sapiens OX=9606 GN=DCAF7 PE=1 SV=1 6.41 2000.9 - 611366 - - - 4.0681 - 1.88 0.301 - 459.3 1 1 0 0.0049 10 0 0 0 4.92E+06 5.78E+06 - - - 3.0247 0.9983 221125_WJC_METTL3_EV_vs_WT_F06.09843.09843.2 0.00469 24-Sep K.GPGEVAGTVTGQK[136.11].R "sp|Q86U44|MTA70_HUMAN,tr|F5H6D8|F5H6D8_HUMAN,tr|H0YFV6|H0YFV6_HUMAN,tr|B4DTN4|B4DTN4_HUMAN" 4 1207.6288 0.15 79773 9843 2 1207.628066 604.8217 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 6 2001.1 - 556586 - - - -0.6211 - 1.757 0.199 - 245.4 1 2 0 -0.0008 13 0 0 0 1.78E+06 1.20E+07 - - - 1.9571 0.9998 221125_WJC_METTL3_EV_vs_WT_F06.09845.09845.2 0.000245 20-Aug K.K[136.11]LDDSYSEAVR[166.11].Q sp|Q86UP2|KTN1_HUMAN 1 1299.6426 9.58 79775 9845 2 1299.643457 650.8286 Kinectin OS=Homo sapiens OX=9606 GN=KTN1 PE=1 SV=1 4.56 2001.3 - 238816 - - - 0.6863 - 1.933 0.462 - 155.8 1 2 0 0.0009 11 0 0 0 1.87E+07 1.96E+06 - - - 4.236 0.9998 221125_WJC_METTL3_EV_vs_WT_F06.09849.09849.2 0.00011 16-Nov R.NFVSHLNQR[166.11].H sp|Q8WVD3|RN138_HUMAN 1 1123.5762 1.32 79777 9849 2 1123.575802 562.7954 E3 ubiquitin-protein ligase RNF138 OS=Homo sapiens OX=9606 GN=RNF138 PE=1 SV=1 9.76 2001.8 - 2.81E+06 - - - -0.3631 - 2.015 0.405 - 554.3 1 2 0 -0.0004 9 0 0 0 6.58E+07 5.01E+07 - - - 4.0591 0.9996 221125_WJC_METTL3_EV_vs_WT_F06.09852.09852.3 0.0018 Nov-40 K.KEEELQGALAR.G sp|P35580|MYH10_HUMAN 1 1242.6568 0.88 79780 9852 3 1242.656981 415.2262 Myosin-10 OS=Homo sapiens OX=9606 GN=MYH10 PE=1 SV=3 4.79 2002 - 2.11E+06 - - - 0.1336 - 2.031 0.318 - 169.3 1 2 0 0.0002 11 0 0 0 1.04E+08 1.19E+08 - - - 4.0981 0.9991 221125_WJC_METTL3_EV_vs_WT_F06.09853.09853.3 0.0241 Oct-48 R.YVGFGNTPPPQKK.E "sp|Q8N6T3|ARFG1_HUMAN,tr|F8VWH9|F8VWH9_HUMAN,tr|E5RHT6|E5RHT6_HUMAN,tr|F8W1U7|F8W1U7_HUMAN,tr|E5RHC5|E5RHC5_HUMAN" 5 1431.7511 1.78 79781 9853 3 1431.749602 478.2576 ADP-ribosylation factor GTPase-activating protein 1 OS=Homo sapiens OX=9606 GN=ARFGAP1 PE=1 SV=2 9.7 2002.1 - 2.01E+06 - - - -1.0113 - 1.714 0.302 - 76.8 1 2 0 -0.0014 13 0 0 0 4.61E+07 2.59E+07 - - - 3.3675 0.9994 221125_WJC_METTL3_EV_vs_WT_F06.09858.09858.2 0.0196 20-Nov K.K[136.11]EEELQGALAR[166.11].G sp|P35580|MYH10_HUMAN 1 1260.6793 0.88 79786 9858 2 1260.680002 631.3469 Myosin-10 OS=Homo sapiens OX=9606 GN=MYH10 PE=1 SV=3 4.79 2002.5 - 3.01E+06 - - - 0.5687 - 1.791 0.326 - 302.4 1 2 0 0.0007 11 0 0 0 2.59E+07 2.95E+07 - - - 3.0252 0.9993 221125_WJC_METTL3_EV_vs_WT_F06.09860.09860.2 0.0014 28-Jul R.INPPSSGGTSSSPIK.A "sp|P14859|PO2F1_HUMAN,tr|A0A0C4DG88|A0A0C4DG88_HUMAN,tr|A0A0A0MT46|A0A0A0MT46_HUMAN" 3 1427.7256 1.53 79788 9860 2 1427.726143 714.8701 "POU domain, class 2, transcription factor 1 OS=Homo sapiens OX=9606 GN=POU2F1 PE=1 SV=2" 8.75 2002.8 - 471918 - - - 0.3642 - 1.679 0.358 - 50.5 3 2 0 0.0005 15 0 0 0 3.26E+07 2.14E+07 - - - 2.7459 0.9981 221125_WJC_METTL3_EV_vs_WT_F06.09873.09873.3 0.0181 14/40 R.LQHLQASLSQR[166.11].L sp|O94761|RECQ4_HUMAN 1 1289.708 1.92 79799 9873 3 1289.707888 430.9099 ATP-dependent DNA helicase Q4 OS=Homo sapiens OX=9606 GN=RECQL4 PE=1 SV=2 9.76 2004.1 - 1.88E+06 - - - -0.0504 - 2.248 0.182 - 445.4 1 2 0 -0.0001 11 0 0 0 3.94E+07 2.05E+07 - - - 2.8703 0.9999 221125_WJC_METTL3_EV_vs_WT_F06.09874.09874.3 0.000204 14/44 R.FVTPSEPVAHSR[166.11].R "sp|O14654|IRS4_HUMAN,tr|A0A804CF45|A0A804CF45_HUMAN" 2 1335.6811 0.64 79800 9874 3 1335.68292 446.2343 Insulin receptor substrate 4 OS=Homo sapiens OX=9606 GN=IRS4 PE=1 SV=1 6.75 2004.2 - 1.44E+06 - - - 1.3851 - 2.423 0.452 - 250.9 1 2 0 0.0019 12 0 0 0 5.38E+07 8.46E+07 - - - 6.0319 0.9999 221125_WJC_METTL3_EV_vs_WT_F06.09875.09875.2 0.00412 16/20 K.KEEELQGALAR.G sp|P35580|MYH10_HUMAN 1 1242.6568 0.88 79801 9875 2 1242.65626 622.3357 Myosin-10 OS=Homo sapiens OX=9606 GN=MYH10 PE=1 SV=3 4.79 2004.3 - 1.29E+06 - - - -0.4466 - 2.856 0.455 - 977.6 1 2 0 -0.0006 11 0 0 0 2.59E+07 2.95E+07 - - - 5.2404 0.9965 221125_WJC_METTL3_EV_vs_WT_F06.09876.09876.3 1.03E-07 14/40 F.FAVYDGHAGSR.V "sp|O75688|PPM1B_HUMAN,tr|B8ZZF0|B8ZZF0_HUMAN,tr|A0A3B3IS24|A0A3B3IS24_HUMAN,tr|C9JIR6|C9JIR6_HUMAN" 4 1178.5469 1.7 79802 9876 3 1178.545057 393.8562 Protein phosphatase 1B OS=Homo sapiens OX=9606 GN=PPM1B PE=1 SV=1 6.74 2004.4 - 1.29E+06 - - - -1.5392 - 2.865 0.467 - 224.9 1 1 0 -0.0018 11 0 0 0 1.28E+07 7.57E+06 - - - 6.7363 0.9997 221125_WJC_METTL3_EV_vs_WT_F06.09878.09878.2 2.70E-05 20-Dec R.AQDIQC[160.03]GLQSR.H "sp|Q8WVJ2|NUDC2_HUMAN,tr|E5RFP0|E5RFP0_HUMAN" 2 1274.6037 0.51 79804 9878 2 1274.601954 638.3091 NudC domain-containing protein 2 OS=Homo sapiens OX=9606 GN=NUDCD2 PE=1 SV=1 5.87 2004.6 - 978785 - - - -1.3965 - 2.137 0.397 - 570.5 1 2 0 -0.0018 11 0 0 0 6.86E+06 1.35E+07 - - - 4.027 0.9998 221125_WJC_METTL3_EV_vs_WT_F06.09882.09882.2 5.63E-06 28-Sep R.INPPSSGGTSSSPIK[136.11].A "sp|P14859|PO2F1_HUMAN,tr|A0A0C4DG88|A0A0C4DG88_HUMAN,tr|A0A0A0MT46|A0A0A0MT46_HUMAN" 3 1435.7398 1.65 79808 9882 2 1435.739111 718.8772 "POU domain, class 2, transcription factor 1 OS=Homo sapiens OX=9606 GN=POU2F1 PE=1 SV=2" 8.75 2005.1 - 328144 - - - -0.4959 - 1.785 0.531 - 101.1 1 2 0 -0.0007 15 0 0 0 4.19E+07 2.53E+07 - - - 4.3873 1 221125_WJC_METTL3_EV_vs_WT_F06.09888.09888.3 6.69E-06 17/56 K.IIDSDEGPEC[160.03]HPPVK.V sp|Q08554|DSC1_HUMAN 1 1691.7825 122.22 79812 9888 3 1691.784481 564.9348 Desmocollin-1 OS=Homo sapiens OX=9606 GN=DSC1 PE=1 SV=2 4.31 2005.9 - 3.12E+06 - - - 1.1792 - 2.955 0.559 - 357.7 1 2 0 0.002 15 0 0 0 5.70E+07 4.66E+05 - - - 7.599 0.9999 221125_WJC_METTL3_EV_vs_WT_F06.09891.09891.2 0.00435 22-Nov K.SNIEETTISSQK.L sp|Q16352|AINX_HUMAN 1 1335.6518 1.63 79815 9891 2 1335.650732 668.8332 Alpha-internexin OS=Homo sapiens OX=9606 GN=INA PE=1 SV=2 4.53 2006.1 - 1.69E+06 - - - -0.7914 - 2.299 0.467 - 318.2 1 2 0 -0.0011 12 0 0 0 2.84E+07 1.74E+07 - - - 4.6803 0.9999 221125_WJC_METTL3_EV_vs_WT_F06.09894.09894.2 2.30E-05 22-Nov K.VGGTSDVEVNEK.K "sp|P10809|CH60_HUMAN,tr|A0A7I2V2X6|A0A7I2V2X6_HUMAN,tr|A0A7I2YQK6|A0A7I2YQK6_HUMAN,tr|A0A7I2V599|A0A7I2V599_HUMAN" 4 1232.5885 1.26 79818 9894 2 1232.5886 617.3015 "60 kDa heat shock protein, mitochondrial OS=Homo sapiens OX=9606 GN=HSPD1 PE=1 SV=2" 4.14 2006.5 - 308185 - - - 0.1128 - 2.284 0.554 - 325.5 1 2 0 0.0001 12 0 0 0 6.81E+06 5.41E+06 - - - 5.306 0.9995 221125_WJC_METTL3_EV_vs_WT_F06.09895.09895.2 0.00104 20-Oct K.NVQQQLDATSR[166.11].N sp|Q9BVW5|TIPIN_HUMAN 1 1268.6348 0.67 79819 9895 2 1268.636933 635.3247 TIMELESS-interacting protein OS=Homo sapiens OX=9606 GN=TIPIN PE=1 SV=2 5.84 2006.6 - 304150 - - - 1.6435 - 2.147 0.337 - 393 1 2 0 0.0021 11 0 0 0 2.64E+06 3.95E+06 - - - 3.5964 0.9999 221125_WJC_METTL3_EV_vs_WT_F06.09897.09897.3 0.00301 Sep-44 K.GNMDEAHIDQVR[166.11].R sp|Q1ED39|KNOP1_HUMAN 1 1393.6284 0.84 79821 9897 3 1393.62811 465.5501 Lysine-rich nucleolar protein 1 OS=Homo sapiens OX=9606 GN=KNOP1 PE=1 SV=1 4.54 2006.9 - 260628 - - - -0.1952 - 1.75 0.426 - 107.6 1 2 0 -0.0003 12 0 0 0 2.72E+06 3.24E+06 - - - 4.8406 0.991 221125_WJC_METTL3_EV_vs_WT_F06.09901.09901.3 0.0023 14/44 A.SAHLPAPAAVGR.R sp|Q8ND56|LS14A_HUMAN 1 1145.6305 1.23 79823 9901 3 1145.631015 382.8841 Protein LSM14 homolog A OS=Homo sapiens OX=9606 GN=LSM14A PE=1 SV=3 9.49 2007.4 - 1.54E+06 - - - 0.4137 - 2.516 0.38 - 353 1 1 0 0.0005 12 0 0 0 3.24E+07 2.64E+07 - - - 5.334 0.9996 221125_WJC_METTL3_EV_vs_WT_F06.09904.09904.2 9.68E-07 20-Sep K.EDSSSTEFVEK[136.11].R "sp|O60749|SNX2_HUMAN,tr|D6RC15|D6RC15_HUMAN" 2 1264.555 0.53 79826 9904 2 1264.551586 633.2848 Sorting nexin-2 OS=Homo sapiens OX=9606 GN=SNX2 PE=1 SV=2 4 2007.6 - 900168 - - - -2.733 - 2.115 0.53 - 291.5 1 2 0 -0.0035 11 0 0 0 5.87E+06 1.11E+07 - - - 4.9809 0.9999 221125_WJC_METTL3_EV_vs_WT_F06.09905.09905.3 8.93E-07 13/44 R.FEEEIK[136.11]AEQEER[166.11].K sp|Q96C19|EFHD2_HUMAN 1 1553.7328 1.52 79827 9905 3 1553.734104 518.9182 EF-hand domain-containing protein D2 OS=Homo sapiens OX=9606 GN=EFHD2 PE=1 SV=1 4.21 2007.7 - 713129 - - - 0.8155 - 2.431 0.525 - 169.5 1 2 1 0.0013 12 0 0 0 1.11E+07 7.34E+06 - - - 6.8551 0.9992 221125_WJC_METTL3_EV_vs_WT_F06.09907.09907.2 0.00723 18-Aug R.EIQQELSSGR.N "sp|P18583|SON_HUMAN,tr|J3QSZ5|J3QSZ5_HUMAN" 2 1145.5677 3.06 79829 9907 2 1145.569307 573.7911 Protein SON OS=Homo sapiens OX=9606 GN=SON PE=1 SV=4 4.53 2007.9 - 320797 - - - 1.4325 - 1.561 0.377 - 175.2 1 2 0 0.0016 10 0 0 0 3.65E+06 1.19E+06 - - - 3.068 0.9435 221125_WJC_METTL3_EV_vs_WT_F06.09908.09908.2 0.142 20-May R.LVSSDPEINTK.K sp|Q9Y266|NUDC_HUMAN 1 1201.619 0.69 79830 9908 2 1201.621473 601.8168 Nuclear migration protein nudC OS=Homo sapiens OX=9606 GN=NUDC PE=1 SV=1 4.37 2008.1 - 253397 - - - 2.0306 - 1.21 0.134 - 56.6 15 2 0 0.0024 11 0 0 0 2.12E+06 3.09E+06 - - - 0.0203 0.999 221125_WJC_METTL3_EV_vs_WT_F06.09910.09910.2 1.85E-06 22-Jul R.FAQSSNYAQHLR.V sp|Q7L3S4|ZN771_HUMAN 1 1420.6848 3.53 79832 9910 2 1420.679246 711.3497 Zinc finger protein 771 OS=Homo sapiens OX=9606 GN=ZNF771 PE=1 SV=1 8.75 2008.3 - 191242 - - - -3.8819 - 2.134 0.516 - 174.8 1 2 0 -0.0055 12 0 0 0 3.27E+06 9.26E+05 - - - 4.8449 0.9998 221125_WJC_METTL3_EV_vs_WT_F06.09918.09918.3 2.84E-05 Dec-44 R.FEEEIKAEQEER.K sp|Q96C19|EFHD2_HUMAN 1 1535.7104 1.5 79838 9918 3 1535.710706 512.9107 EF-hand domain-containing protein D2 OS=Homo sapiens OX=9606 GN=EFHD2 PE=1 SV=1 4.21 2009.1 - 770124 - - - 0.2207 - 2.362 0.488 - 132.6 1 2 1 0.0003 12 0 0 0 1.13E+07 7.57E+06 - - - 6.3631 0.9995 221125_WJC_METTL3_EV_vs_WT_F06.09926.09926.3 0.000694 13/44 K.LDK[136.11]ANEEIAQVR[166.11].T "sp|O75410|TACC1_HUMAN,tr|E7EVI4|E7EVI4_HUMAN,tr|B4E3H6|B4E3H6_HUMAN,tr|H0YAY0|H0YAY0_HUMAN,tr|H0YBT8|H0YBT8_HUMAN,tr|E7ET87|E7ET87_HUMAN" 6 1402.7535 1.47 79844 9926 3 1402.755137 468.5918 Transforming acidic coiled-coil-containing protein 1 OS=Homo sapiens OX=9606 GN=TACC1 PE=1 SV=2 4.68 2010.1 - 1.39E+06 - - - 1.1577 - 2.254 0.411 - 243.1 1 2 1 0.0016 12 0 0 0 4.49E+07 3.07E+07 - - - 5.3745 0.9989 221125_WJC_METTL3_EV_vs_WT_F06.09929.09929.3 0.0936 13/36 K.SR[166.11]GC[160.03]AVVEFK[136.11].M "sp|P52272|HNRPM_HUMAN,tr|M0R019|M0R019_HUMAN,tr|M0R0N3|M0R0N3_HUMAN,tr|M0R2T0|M0R2T0_HUMAN" 4 1169.5982 1.26 79847 9929 3 1169.598232 390.8733 Heterogeneous nuclear ribonucleoprotein M OS=Homo sapiens OX=9606 GN=HNRNPM PE=1 SV=3 7.94 2010.4 - 966133 - - - 0.0291 - 2.159 0.326 - 389.7 1 2 1 0 10 0 0 0 2.65E+07 2.10E+07 - - - 4.4223 0.9027 221125_WJC_METTL3_EV_vs_WT_F06.09930.09930.3 0.00436 Oct-36 L.TC[160.03]PFEPPK[136.11]PK[136.11].T "sp|P48643|TCPE_HUMAN,tr|E9PCA1|E9PCA1_HUMAN,tr|B7ZAR1|B7ZAR1_HUMAN,tr|E7ENZ3|E7ENZ3_HUMAN" 4 1215.6293 0.44 79848 9930 3 1215.629789 406.217 T-complex protein 1 subunit epsilon OS=Homo sapiens OX=9606 GN=CCT5 PE=1 SV=1 7.87 2010.5 - 706911 - - - 0.4187 - 1.924 0.255 - 164.4 1 1 0 0.0005 10 0 0 0 6.92E+06 1.59E+07 - - - 3.294 0.9999 221125_WJC_METTL3_EV_vs_WT_F06.09940.09940.3 2.28E-05 Nov-44 K.NC[160.03]PHIVVGTPGR.L "sp|Q13838|DX39B_HUMAN,tr|A0A140TA18|A0A140TA18_HUMAN,tr|F6UJC5|F6UJC5_HUMAN,tr|F6TRA5|F6TRA5_HUMAN,tr|F6WLT2|F6WLT2_HUMAN,tr|Q5STU3|Q5STU3_HUMAN,tr|A0A140T973|A0A140T973_HUMAN,tr|A0A140T9X9|A0A140T9X9_HUMAN,tr|A0A140T996|A0A140T996_HUMAN,tr|A0A140T9L4|A0A140T9L4_HUMAN,tr|A0A0G2JJZ9|A0A0G2JJZ9_HUMAN,tr|A0A140T9K1|A0A140T9K1_HUMAN,tr|A0A140T9X3|A0A140T9X3_HUMAN,tr|F6S4E6|F6S4E6_HUMAN,tr|A0A0A0MT12|A0A0A0MT12_HUMAN" 15 1305.6612 1.29 79857 9940 3 1305.662969 436.2277 Spliceosome RNA helicase DDX39B OS=Homo sapiens OX=9606 GN=DDX39B PE=1 SV=1 8.26 2011.8 - 664604 - - - 1.3633 - 2.227 0.464 - 204.5 1 2 0 0.0018 12 0 0 0 1.65E+07 1.27E+07 - - - 5.9319 0.9999 221125_WJC_METTL3_EV_vs_WT_F06.09942.09942.3 4.36E-05 Dec-40 K.EAIEGTYIDKK.C "sp|P62280|RS11_HUMAN,tr|M0QZC5|M0QZC5_HUMAN" 2 1265.6503 1 79858 9942 3 1265.650947 422.8907 40S ribosomal protein S11 OS=Homo sapiens OX=9606 GN=RPS11 PE=1 SV=3 4.68 2012 - 2.61E+07 - - - 0.4851 - 2.23 0.43 - 205.1 1 2 0 0.0006 11 0 0 0 1.04E+09 1.04E+09 - - - 5.6123 0.9999 221125_WJC_METTL3_EV_vs_WT_F06.09943.09943.2 1.62E-05 20-Nov K.EAIEGTYIDKK.C "sp|P62280|RS11_HUMAN,tr|M0QZC5|M0QZC5_HUMAN" 2 1265.6503 0.96 79859 9943 2 1265.650915 633.8324 40S ribosomal protein S11 OS=Homo sapiens OX=9606 GN=RPS11 PE=1 SV=3 4.68 2012 - 6.35E+06 - - - 0.4598 - 2.302 0.502 - 531.5 1 2 0 0.0006 11 0 0 0 2.74E+08 2.86E+08 - - - 5.0042 0.9995 221125_WJC_METTL3_EV_vs_WT_F06.09944.09944.3 0.000215 13/44 K.LDKANEEIAQVR.T "sp|O75410|TACC1_HUMAN,tr|E7EVI4|E7EVI4_HUMAN,tr|B4E3H6|B4E3H6_HUMAN,tr|H0YAY0|H0YAY0_HUMAN,tr|H0YBT8|H0YBT8_HUMAN,tr|E7ET87|E7ET87_HUMAN" 6 1384.731 1.39 79860 9944 3 1384.730872 462.5843 Transforming acidic coiled-coil-containing protein 1 OS=Homo sapiens OX=9606 GN=TACC1 PE=1 SV=2 4.68 2012.1 - 4.52E+06 - - - -0.1235 - 2.644 0.342 - 237 1 2 1 -0.0002 12 0 0 0 4.27E+07 3.07E+07 - - - 5.048 0.9997 221125_WJC_METTL3_EV_vs_WT_F06.09945.09945.3 3.89E-05 14/36 K.SRGC[160.03]AVVEFK.M "sp|P52272|HNRPM_HUMAN,tr|M0R019|M0R019_HUMAN,tr|M0R0N3|M0R0N3_HUMAN,tr|M0R2T0|M0R2T0_HUMAN" 4 1151.5757 1.27 79861 9945 3 1151.57685 384.8659 Heterogeneous nuclear ribonucleoprotein M OS=Homo sapiens OX=9606 GN=HNRNPM PE=1 SV=3 7.94 2012.1 - 2.87E+06 - - - 0.9743 - 2.011 0.46 - 411.7 1 2 1 0.0011 10 0 0 0 2.63E+07 2.07E+07 - - - 5.7085 0.9999 221125_WJC_METTL3_EV_vs_WT_F06.09947.09947.2 3.64E-05 22-Nov R.QAASSLQQASLK[136.11].L "sp|P38646|GRP75_HUMAN,tr|A0A7I2V2S7|A0A7I2V2S7_HUMAN,tr|A0A7I2V2G2|A0A7I2V2G2_HUMAN,tr|A0A7I2V3F7|A0A7I2V3F7_HUMAN,tr|A0A7I2YQB2|A0A7I2YQB2_HUMAN,tr|D6RCD7|D6RCD7_HUMAN" 6 1238.671 0.42 79863 9947 2 1238.67163 620.3428 "Stress-70 protein, mitochondrial OS=Homo sapiens OX=9606 GN=HSPA9 PE=1 SV=2" 8.75 2012.3 - 961401 - - - 0.4965 - 2.669 0.44 - 560.8 1 2 0 0.0006 12 0 0 0 2.54E+07 6.00E+07 - - - 4.8737 0.9809 221125_WJC_METTL3_EV_vs_WT_F06.09949.09949.2 0.217 18-Nov K.SR[166.11]GC[160.03]AVVEFK[136.11].M "sp|P52272|HNRPM_HUMAN,tr|M0R019|M0R019_HUMAN,tr|M0R0N3|M0R0N3_HUMAN,tr|M0R2T0|M0R2T0_HUMAN" 4 1169.5982 1.55 79865 9949 2 1169.600141 585.8064 Heterogeneous nuclear ribonucleoprotein M OS=Homo sapiens OX=9606 GN=HNRNPM PE=1 SV=3 7.94 2012.5 - 564674 - - - 1.6613 - 1.879 0.222 - 511.5 1 2 1 0.0019 10 0 0 0 9.13E+06 5.91E+06 - - - 2.4407 0.9749 221125_WJC_METTL3_EV_vs_WT_F06.09951.09951.2 0.00363 16-Oct A.IEGTYIDKK.C "sp|P62280|RS11_HUMAN,tr|M0QZC5|M0QZC5_HUMAN" 2 1065.5706 0.75 79867 9951 2 1065.571671 533.7926 40S ribosomal protein S11 OS=Homo sapiens OX=9606 GN=RPS11 PE=1 SV=3 6.07 2012.8 - 411196 - - - 0.9807 - 1.863 0.357 - 234.4 1 1 0 0.001 9 0 0 0 2.02E+07 2.70E+07 - - - 3.4775 1 221125_WJC_METTL3_EV_vs_WT_F06.09956.09956.3 2.26E-08 16/52 R.KPVSIVSPEPGTTR.D sp|Q969Y2|GTPB3_HUMAN 1 1466.8093 2.16 79870 9956 3 1466.809614 489.9437 "tRNA modification GTPase GTPBP3, mitochondrial OS=Homo sapiens OX=9606 GN=GTPBP3 PE=1 SV=2" 8.75 2013.3 - 1.11E+06 - - - 0.2188 - 3.128 0.469 - 272.7 1 2 0 0.0003 14 0 0 0 7.03E+07 3.26E+07 - - - 6.7994 0.9987 221125_WJC_METTL3_EV_vs_WT_F06.09959.09959.2 1.06E-05 15/22 K.LDKANEEIAQVR.T "sp|O75410|TACC1_HUMAN,tr|E7EVI4|E7EVI4_HUMAN,tr|B4E3H6|B4E3H6_HUMAN,tr|H0YAY0|H0YAY0_HUMAN,tr|H0YBT8|H0YBT8_HUMAN,tr|E7ET87|E7ET87_HUMAN" 6 1384.731 1.47 79873 9959 2 1384.729603 693.3728 Transforming acidic coiled-coil-containing protein 1 OS=Homo sapiens OX=9606 GN=TACC1 PE=1 SV=2 4.68 2013.6 - 886682 - - - -1.0399 - 2.495 0.515 - 707.7 1 2 1 -0.0014 12 0 0 0 8.88E+06 6.05E+06 - - - 5.25 1 221125_WJC_METTL3_EV_vs_WT_F06.09960.09960.3 1.92E-07 16/64 R.LLEPHEAGGAGGNINAR.D "sp|O95872|GPAN1_HUMAN,tr|A0A0G2JK30|A0A0G2JK30_HUMAN,tr|A0A0G2JJ73|A0A0G2JJ73_HUMAN,tr|F6QYZ9|F6QYZ9_HUMAN,tr|A0A0A0MSL4|A0A0A0MSL4_HUMAN,tr|A0A0G2JK37|A0A0G2JK37_HUMAN,tr|A0A0G2JHL1|A0A0G2JHL1_HUMAN,tr|A0A0G2JKD0|A0A0G2JKD0_HUMAN" 8 1674.8438 3.11 79874 9960 3 1674.842539 559.2885 G patch domain and ankyrin repeat-containing protein 1 OS=Homo sapiens OX=9606 GN=GPANK1 PE=1 SV=1 5.4 2013.8 - 738178 - - - -0.7416 - 2.778 0.5 - 355.8 1 2 0 -0.0012 17 0 0 0 1.54E+07 4.94E+06 - - - 6.6954 0.9999 221125_WJC_METTL3_EV_vs_WT_F06.09961.09961.2 4.82E-06 18-Nov K.DNGNIELENK.K sp|Q9Y5T5|UBP16_HUMAN 1 1144.536 1.94 79875 9961 2 1144.535692 573.2753 Ubiquitin carboxyl-terminal hydrolase 16 OS=Homo sapiens OX=9606 GN=USP16 PE=1 SV=1 4.14 2013.9 - 630572 - - - -0.2962 - 2.064 0.52 - 525.5 1 2 0 -0.0003 10 0 0 0 9.96E+06 5.12E+06 - - - 4.9043 0.9998 221125_WJC_METTL3_EV_vs_WT_F06.09962.09962.2 6.99E-05 20-Nov K.EAIEGTYIDK[136.11]K.C "sp|P62280|RS11_HUMAN,tr|M0QZC5|M0QZC5_HUMAN" 2 1273.6645 - 79876 9962 2 1273.665192 637.8395 40S ribosomal protein S11 OS=Homo sapiens OX=9606 GN=RPS11 PE=1 SV=3 4.68 2014 - 342076 - - - 0.5174 - 2.153 0.444 - 503.5 1 2 0 0.0007 11 0 0 0 - - - - - 4.3947 0.9986 221125_WJC_METTL3_EV_vs_WT_F06.09965.09965.2 1.33E-05 22-Nov R.EENAEQQALAAK[136.11].R sp|Q9UQE7|SMC3_HUMAN 1 1308.6401 0.77 79879 9965 2 1308.634712 655.3273 Structural maintenance of chromosomes protein 3 OS=Homo sapiens OX=9606 GN=SMC3 PE=1 SV=2 4.25 2014.4 - 303082 - - - -4.1241 - 2.088 0.5 - 512.3 1 2 0 -0.0054 12 0 0 0 4.48E+06 5.81E+06 - - - 4.6694 0.9931 221125_WJC_METTL3_EV_vs_WT_F06.09973.09973.3 0.00169 Nov-40 K.LR[166.11]EYEAALNSK[136.11].D "sp|P20700|LMNB1_HUMAN,tr|A0A0D9SFY5|A0A0D9SFY5_HUMAN,tr|E9PBF6|E9PBF6_HUMAN,tr|A0A0D9SFE5|A0A0D9SFE5_HUMAN" 4 1310.6949 1.6 79885 9973 3 1310.693155 437.9056 Lamin-B1 OS=Homo sapiens OX=9606 GN=LMNB1 PE=1 SV=2 6.14 2015.4 - 2.79E+06 - - - -1.3581 - 2.335 0.197 - 324 1 2 1 -0.0018 11 0 0 0 1.14E+08 7.11E+07 - - - 3.1449 0.9999 221125_WJC_METTL3_EV_vs_WT_F06.09974.09974.3 4.10E-05 Nov-40 K.EAIEGTYIDK[136.11]K.C "sp|P62280|RS11_HUMAN,tr|M0QZC5|M0QZC5_HUMAN" 2 1273.6645 - 79886 9974 3 1273.664082 425.5621 40S ribosomal protein S11 OS=Homo sapiens OX=9606 GN=RPS11 PE=1 SV=3 4.68 2015.4 - 2.27E+06 - - - -0.3541 - 2.136 0.428 - 155.6 1 2 0 -0.0005 11 0 0 0 - - - - - 5.4677 0.9986 221125_WJC_METTL3_EV_vs_WT_F06.09975.09975.3 0.0647 Nov-40 K.LREYEAALNSK.D "sp|P20700|LMNB1_HUMAN,tr|A0A0D9SFY5|A0A0D9SFY5_HUMAN,tr|E9PBF6|E9PBF6_HUMAN,tr|A0A0D9SFE5|A0A0D9SFE5_HUMAN" 4 1292.6725 1.13 79887 9975 3 1292.668646 431.8981 Lamin-B1 OS=Homo sapiens OX=9606 GN=LMNB1 PE=1 SV=2 6.14 2015.5 - 2.32E+06 - - - -2.9543 - 2.558 0.375 - 335.3 1 2 1 -0.0038 11 0 0 0 7.98E+07 7.08E+07 - - - 5.388 0.9999 221125_WJC_METTL3_EV_vs_WT_F06.09976.09976.3 0.000216 Dec-36 R.TQQMLHGLQR.A "sp|O60216|RAD21_HUMAN,tr|E5RI01|E5RI01_HUMAN,tr|E5RFZ5|E5RFZ5_HUMAN" 3 1210.6241 0.56 79888 9976 3 1210.622437 404.5486 Double-strand-break repair protein rad21 homolog OS=Homo sapiens OX=9606 GN=RAD21 PE=1 SV=2 9.44 2015.6 - 1.88E+06 - - - -1.353 - 2.153 0.43 - 301.5 1 2 0 -0.0016 10 0 0 0 2.49E+07 4.46E+07 - - - 5.5732 1 221125_WJC_METTL3_EV_vs_WT_F06.09978.09978.3 0.000298 18/52 R.K[136.11]PVSIVSPEPGTTR[166.11].D sp|Q969Y2|GTPB3_HUMAN 1 1484.8318 2.16 79890 9978 3 1484.831666 495.9512 "tRNA modification GTPase GTPBP3, mitochondrial OS=Homo sapiens OX=9606 GN=GTPBP3 PE=1 SV=2" 8.75 2015.8 - 1.31E+06 - - - -0.0653 - 3.565 0.489 - 385.2 1 2 0 -0.0001 14 0 0 0 7.03E+07 3.26E+07 - - - 7.37 0.8834 221125_WJC_METTL3_EV_vs_WT_F06.09979.09979.2 0.442 18-Oct E.AIEGTYIDKK.C "sp|P62280|RS11_HUMAN,tr|M0QZC5|M0QZC5_HUMAN" 2 1136.6077 1.08 79891 9979 2 1136.605859 569.3111 40S ribosomal protein S11 OS=Homo sapiens OX=9606 GN=RPS11 PE=1 SV=3 6.11 2015.9 - 1.24E+06 - - - -1.6549 - 1.861 0.187 - 235.8 1 1 0 -0.0019 10 0 0 0 1.02E+07 9.47E+06 - - - 2.1553 0.9982 221125_WJC_METTL3_EV_vs_WT_F06.09981.09981.2 0.00213 16-Sep R.DSDIQQLQK.Q "sp|Q9NPJ6|MED4_HUMAN,tr|Q5T911|Q5T911_HUMAN" 2 1073.5353 1.36 79893 9981 2 1073.533032 537.7749 Mediator of RNA polymerase II transcription subunit 4 OS=Homo sapiens OX=9606 GN=MED4 PE=1 SV=1 4.21 2016.1 - 857001 - - - -2.1154 - 1.528 0.316 - 307 1 2 0 -0.0023 9 0 0 0 9.21E+06 6.75E+06 - - - 2.6008 0.9979 221125_WJC_METTL3_EV_vs_WT_F06.09982.09982.2 0.0014 14/20 K.LR[166.11]EYEAALNSK[136.11].D "sp|P20700|LMNB1_HUMAN,tr|A0A0D9SFY5|A0A0D9SFY5_HUMAN,tr|E9PBF6|E9PBF6_HUMAN,tr|A0A0D9SFE5|A0A0D9SFE5_HUMAN" 4 1310.6949 1.67 79894 9982 2 1310.69513 656.3547 Lamin-B1 OS=Homo sapiens OX=9606 GN=LMNB1 PE=1 SV=2 6.14 2016.2 - 766349 - - - 0.1488 - 2.758 0.327 - 834.4 1 2 1 0.0002 11 0 0 0 3.18E+07 1.90E+07 - - - 4.2006 0.9977 221125_WJC_METTL3_EV_vs_WT_F06.09983.09983.2 0.479 15/20 K.LREYEAALNSK.D "sp|P20700|LMNB1_HUMAN,tr|A0A0D9SFY5|A0A0D9SFY5_HUMAN,tr|E9PBF6|E9PBF6_HUMAN,tr|A0A0D9SFE5|A0A0D9SFE5_HUMAN" 4 1292.6725 1.39 79895 9983 2 1292.671961 647.3435 Lamin-B1 OS=Homo sapiens OX=9606 GN=LMNB1 PE=1 SV=2 6.14 2016.3 - 675325 - - - -0.3899 - 2.772 0.302 - 780.8 1 2 1 -0.0005 11 0 0 0 2.63E+07 1.90E+07 - - - 4.0296 0.9867 221125_WJC_METTL3_EV_vs_WT_F06.09989.09989.3 2.24 Nov-36 K.TTIHQLTMQK.E sp|P15924|DESP_HUMAN 1 1199.6332 7.54 79899 9989 3 1199.633136 400.885 Desmoplakin OS=Homo sapiens OX=9606 GN=DSP PE=1 SV=3 8.44 2017.1 - 2.37E+06 - - - -0.0892 - 1.984 0.098 - 165.8 1 2 0 -0.0001 10 0 0 0 2.57E+07 3.41E+06 - - - 1.6334 0.9998 221125_WJC_METTL3_EV_vs_WT_F06.09991.09991.2 0.000436 18-Dec R.TQQMLHGLQR[166.11].A "sp|O60216|RAD21_HUMAN,tr|E5RI01|E5RI01_HUMAN,tr|E5RFZ5|E5RFZ5_HUMAN" 3 1220.6323 0.97 79901 9991 2 1220.631431 611.3234 Double-strand-break repair protein rad21 homolog OS=Homo sapiens OX=9606 GN=RAD21 PE=1 SV=2 9.44 2017.3 - 653540 - - - -0.7488 - 2.26 0.356 - 797.4 1 2 0 -0.0009 10 0 0 0 4.36E+06 4.49E+06 - - - 3.9461 0.9998 221125_WJC_METTL3_EV_vs_WT_F06.09992.09992.3 3.14E-06 18/56 R.LEPKPQPPVAEATPR.S "sp|Q9UHD8|SEPT9_HUMAN,tr|K7ER14|K7ER14_HUMAN,tr|K7EJ51|K7EJ51_HUMAN" 3 1628.8886 1.03 79902 9992 3 1628.883946 543.9701 Septin-9 OS=Homo sapiens OX=9606 GN=SEPTIN9 PE=1 SV=2 6.14 2017.4 - 532689 - - - -2.8608 - 2.711 0.397 - 453.4 1 2 0 -0.0047 15 0 0 0 1.10E+07 1.07E+07 - - - 5.5672 0.9999 221125_WJC_METTL3_EV_vs_WT_F06.09994.09994.2 3.98E-09 24-Oct K.C[160.03]PPVTPSPPC[160.03]QPK.C "sp|P22531|SPR2E_HUMAN,sp|Q96RM1|SPR2F_HUMAN" 2 1463.6901 999 79904 9994 2 1463.691189 732.8523 Small proline-rich protein 2E OS=Homo sapiens OX=9606 GN=SPRR2E PE=2 SV=2 8.06 2017.6 - 411446 - - - 0.7399 - 2.172 0.625 - 331.6 1 2 0 0.0011 13 0 0 0 4.72E+07 0.00E+00 - - - 5.6476 1 221125_WJC_METTL3_EV_vs_WT_F06.09998.09998.3 0.000789 Dec-40 K.EAIEGTYIDK[136.11]K[136.11].C "sp|P62280|RS11_HUMAN,tr|M0QZC5|M0QZC5_HUMAN" 2 1281.6787 1 79907 9998 3 1281.678004 428.2335 40S ribosomal protein S11 OS=Homo sapiens OX=9606 GN=RPS11 PE=1 SV=3 4.68 2018.1 - 8.99E+07 - - - -0.5688 - 2.135 0.526 - 218.8 1 2 0 -0.0007 11 0 0 0 1.04E+09 1.04E+09 - - - 6.5589 0.9986 221125_WJC_METTL3_EV_vs_WT_F06.10000.10000.2 0.00197 16-Nov K.RINVELSTK.G sp|Q96PK6|RBM14_HUMAN 1 1058.6084 1.87 79909 10000 2 1058.608099 530.3115 RNA-binding protein 14 OS=Homo sapiens OX=9606 GN=RBM14 PE=1 SV=2 8.75 2018.3 - 1.82E+06 - - - -0.2919 - 2.325 0.078 - 482.1 1 2 0 -0.0003 9 0 0 0 2.73E+08 1.46E+08 - - - 2.0579 0.9996 221125_WJC_METTL3_EV_vs_WT_F06.10001.10001.2 0.254 16-Nov K.R[166.11]INVELSTK[136.11].G sp|Q96PK6|RBM14_HUMAN 1 1076.6309 1.87 79910 10001 2 1076.630671 539.3227 RNA-binding protein 14 OS=Homo sapiens OX=9606 GN=RBM14 PE=1 SV=2 8.75 2018.4 - 1.52E+06 - - - -0.1923 - 2.271 0.251 - 513.8 1 2 0 -0.0002 9 0 0 0 2.73E+08 1.46E+08 - - - 3.2678 0.9998 221125_WJC_METTL3_EV_vs_WT_F06.10002.10002.2 5.62E-06 20-Nov R.INISEGNC[160.03]PER[166.11].L "sp|P57721|PCBP3_HUMAN,sp|Q15366|PCBP2_HUMAN,sp|Q15365|PCBP1_HUMAN,tr|F8VTZ0|F8VTZ0_HUMAN,tr|F8W1G6|F8W1G6_HUMAN,tr|E9PFP8|E9PFP8_HUMAN,tr|J3QT27|J3QT27_HUMAN,tr|F8VZX2|F8VZX2_HUMAN,tr|F8W0G4|F8W0G4_HUMAN,tr|F8VXH9|F8VXH9_HUMAN,tr|H3BRU6|H3BRU6_HUMAN" 11 1297.596 1.06 79911 10002 2 1297.594277 649.8053 Poly(rC)-binding protein 3 OS=Homo sapiens OX=9606 GN=PCBP3 PE=1 SV=2 4.53 2018.4 - 1.03E+06 - - - -1.3433 - 2.369 0.416 - 419.7 1 2 0 -0.0017 11 0 0 0 2.38E+08 2.24E+08 - - - 4.4462 0.9999 221125_WJC_METTL3_EV_vs_WT_F06.10003.10003.2 1.17E-06 20-Sep K.DGGNQEVEIAR.C "sp|P13861|KAP2_HUMAN,tr|H7C330|H7C330_HUMAN" 2 1186.5578 2.7 79912 10003 2 1186.557629 594.2862 cAMP-dependent protein kinase type II-alpha regulatory subunit OS=Homo sapiens OX=9606 GN=PRKAR2A PE=1 SV=2 4.14 2018.6 - 687197 - - - -0.1686 - 2.263 0.452 - 402.2 1 2 0 -0.0002 11 0 0 0 1.24E+08 4.59E+07 - - - 4.5888 1 221125_WJC_METTL3_EV_vs_WT_F06.10005.10005.2 1.75E-06 13/32 R.AAVGQESPGGLEAGNAK.A sp|Q29RF7|PDS5A_HUMAN 1 1554.7638 0.84 79914 10005 2 1554.766611 778.3892 Sister chromatid cohesion protein PDS5 homolog A OS=Homo sapiens OX=9606 GN=PDS5A PE=1 SV=1 4.53 2018.8 - 407874 - - - 1.8086 - 2.695 0.623 - 321.8 1 2 0 0.0028 17 0 0 0 5.11E+06 6.09E+06 - - - 6.079 0.9999 221125_WJC_METTL3_EV_vs_WT_F06.10006.10006.2 0.00529 15/32 R.AAVGQESPGGLEAGNAK[136.11].A sp|Q29RF7|PDS5A_HUMAN 1 1562.778 0.84 79915 10006 2 1562.778904 782.3963 Sister chromatid cohesion protein PDS5 homolog A OS=Homo sapiens OX=9606 GN=PDS5A PE=1 SV=1 4.53 2019 - 387031 - - - 0.5791 - 2.961 0.532 - 560.1 1 2 0 0.0009 17 0 0 0 5.11E+06 6.09E+06 - - - 5.6389 0.9999 221125_WJC_METTL3_EV_vs_WT_F06.10012.10012.3 5.52E-05 Dec-48 K.LLGGHNEDLPSNR.H sp|Q9BRD0|BUD13_HUMAN 1 1420.7059 0.84 79919 10012 3 1420.702595 474.5759 BUD13 homolog OS=Homo sapiens OX=9606 GN=BUD13 PE=1 SV=1 5.32 2019.6 - 2.53E+06 - - - -2.32 - 2.324 0.466 - 203.9 1 2 0 -0.0033 13 0 0 0 2.20E+07 2.62E+07 - - - 6.0209 1 221125_WJC_METTL3_EV_vs_WT_F06.10015.10015.3 6.27E-06 15/52 R.VVDNSALGNSPYHR.A sp|Q6P1L8|RM14_HUMAN 1 1527.743 1.1 79922 10015 3 1527.743805 510.2549 "39S ribosomal protein L14, mitochondrial OS=Homo sapiens OX=9606 GN=MRPL14 PE=1 SV=1" 6.71 2019.8 - 1.20E+06 - - - 0.5243 - 2.537 0.44 - 308.7 1 2 0 0.0008 14 0 0 0 7.26E+07 6.61E+07 - - - 5.9195 0.9878 221125_WJC_METTL3_EV_vs_WT_F06.10019.10019.2 0.399 16-Jul K.LHLNVQDDR[166.11].L "sp|Q6ZU65|UBN2_HUMAN,tr|H7C4P8|H7C4P8_HUMAN" 2 1118.5708 0.39 79926 10019 2 1118.568713 560.2927 Ubinuclein-2 OS=Homo sapiens OX=9606 GN=UBN2 PE=1 SV=2 5.21 2020.3 - 380985 - - - -1.8577 - 1.279 0.161 - 140.5 1 2 0 -0.0021 9 0 0 0 2.65E+06 6.78E+06 - - - 0.9414 0.9999 221125_WJC_METTL3_EV_vs_WT_F06.10020.10020.2 0.000332 13/26 R.KPVSIVSPEPGTTR.D sp|Q969Y2|GTPB3_HUMAN 1 1466.8093 2.65 79927 10020 2 1466.809696 734.4119 "tRNA modification GTPase GTPBP3, mitochondrial OS=Homo sapiens OX=9606 GN=GTPBP3 PE=1 SV=2" 8.75 2020.4 - 353655 - - - 0.2747 - 2.853 0.53 - 498.6 1 2 0 0.0004 14 0 0 0 6.05E+06 2.28E+06 - - - 5.5863 0.9913 221125_WJC_METTL3_EV_vs_WT_F06.10021.10021.2 4.1 16-Jul K.REQEVNILK.K sp|P35579|MYH9_HUMAN 1 1127.6299 1.12 79928 10021 2 1127.629273 564.8222 Myosin-9 OS=Homo sapiens OX=9606 GN=MYH9 PE=1 SV=4 6.14 2020.6 - 340828 - - - -0.5312 - 1.553 0.075 - 134.7 2 2 0 -0.0006 9 0 0 0 4.29E+06 3.84E+06 - - - 0.7338 0.9886 221125_WJC_METTL3_EV_vs_WT_F06.10023.10023.2 0.000541 13/18 K.SLKDEDVLQK.L "sp|Q9NZ01|TECR_HUMAN,tr|M0R2N5|M0R2N5_HUMAN" 2 1173.6241 1.21 79930 10023 2 1173.625793 587.8193 Very-long-chain enoyl-CoA reductase OS=Homo sapiens OX=9606 GN=TECR PE=1 SV=1 4.56 2020.8 - 294254 - - - 1.4272 - 2.38 0.182 - 419.4 1 2 1 0.0017 10 0 0 0 5.19E+06 4.29E+06 - - - 2.8051 0.9998 221125_WJC_METTL3_EV_vs_WT_F06.10026.10026.2 0.00119 20-Oct K.EAIEGTYIDK[136.11]K[136.11].C "sp|P62280|RS11_HUMAN,tr|M0QZC5|M0QZC5_HUMAN" 2 1281.6787 0.96 79932 10026 2 1281.679535 641.8466 40S ribosomal protein S11 OS=Homo sapiens OX=9606 GN=RPS11 PE=1 SV=3 4.68 2021.1 - 4.08E+06 - - - 0.6257 - 2.138 0.445 - 501.2 1 2 0 0.0008 11 0 0 0 2.74E+08 2.86E+08 - - - 4.3831 1 221125_WJC_METTL3_EV_vs_WT_F06.10028.10028.3 1.99E-06 16/52 R.VVDNSALGNSPYHR[166.11].A sp|Q6P1L8|RM14_HUMAN 1 1537.7513 1.1 79933 10028 3 1537.752081 513.591 "39S ribosomal protein L14, mitochondrial OS=Homo sapiens OX=9606 GN=MRPL14 PE=1 SV=1" 6.71 2021.4 - 3.03E+06 - - - 0.5248 - 2.752 0.552 - 320.4 1 2 0 0.0008 14 0 0 0 7.25E+07 6.60E+07 - - - 7.3843 0.9999 221125_WJC_METTL3_EV_vs_WT_F06.10029.10029.2 0.0115 20-Oct K.DGGNQEVEIAR[166.11].C "sp|P13861|KAP2_HUMAN,tr|H7C330|H7C330_HUMAN" 2 1196.5661 2.7 79934 10029 2 1196.566708 599.2903 cAMP-dependent protein kinase type II-alpha regulatory subunit OS=Homo sapiens OX=9606 GN=PRKAR2A PE=1 SV=2 4.14 2021.4 - 2.60E+06 - - - 0.509 - 2.394 0.501 - 495.6 1 2 0 0.0006 11 0 0 0 1.24E+08 4.59E+07 - - - 5.1028 0.9997 221125_WJC_METTL3_EV_vs_WT_F06.10030.10030.3 0.0059 Dec-44 R.VVASDKETYELR.Y "sp|Q6P5R6|RL22L_HUMAN,tr|H0Y8C2|H0Y8C2_HUMAN,tr|C9JYQ9|C9JYQ9_HUMAN" 3 1408.7198 1.34 79935 10030 3 1408.719622 470.5805 60S ribosomal protein L22-like 1 OS=Homo sapiens OX=9606 GN=RPL22L1 PE=1 SV=2 4.68 2021.5 - 2.63E+06 - - - -0.1327 - 2.544 0.39 - 219.8 1 2 1 -0.0002 12 0 0 0 3.00E+07 2.24E+07 - - - 5.4762 0.9983 221125_WJC_METTL3_EV_vs_WT_F06.10031.10031.3 0.041 Nov-48 R.QAVPGR[166.11]PGPFPSK[136.11].Q "sp|Q9Y520|PRC2C_HUMAN,tr|A0A0A0MS30|A0A0A0MS30_HUMAN,tr|E7EPN9|E7EPN9_HUMAN" 3 1354.7476 1.14 79936 10031 3 1354.747818 452.5898 Protein PRRC2C OS=Homo sapiens OX=9606 GN=PRRC2C PE=1 SV=4 11 2021.6 - 1.39E+06 - - - 0.1321 - 2.022 0.223 - 169.4 1 2 0 0.0002 13 0 0 0 3.08E+08 2.70E+08 - - - 2.9352 0.9997 221125_WJC_METTL3_EV_vs_WT_F06.10035.10035.2 3.75E-05 26-Nov R.DTASLSTTPSESPR[166.11].A "sp|Q9NQX3|GEPH_HUMAN,tr|G3V582|G3V582_HUMAN,tr|H0YJ30|H0YJ30_HUMAN,tr|F5H039|F5H039_HUMAN" 4 1457.6873 0.76 79940 10035 2 1457.689358 729.8509 Gephyrin OS=Homo sapiens OX=9606 GN=GPHN PE=1 SV=1 4.37 2022 - 468793 - - - 1.3864 - 2.121 0.425 - 380.5 1 2 0 0.002 14 0 0 0 2.95E+06 3.87E+06 - - - 4.0662 1 221125_WJC_METTL3_EV_vs_WT_F06.10037.10037.3 6.94E-07 17/56 R.LEPK[136.11]PQPPVAEATPR[166.11].S "sp|Q9UHD8|SEPT9_HUMAN,tr|K7ER14|K7ER14_HUMAN,tr|K7EJ51|K7EJ51_HUMAN" 3 1646.9111 1.06 79941 10037 3 1646.91205 549.9776 Septin-9 OS=Homo sapiens OX=9606 GN=SEPTIN9 PE=1 SV=2 6.14 2022.3 - 411653 - - - 0.5914 - 2.926 0.537 - 412.5 1 2 0 0.001 15 0 0 0 1.09E+07 1.03E+07 - - - 7.3283 0.9977 221125_WJC_METTL3_EV_vs_WT_F06.10038.10038.2 2.66E-06 22-Dec R.VVASDKETYELR.Y "sp|Q6P5R6|RL22L_HUMAN,tr|H0Y8C2|H0Y8C2_HUMAN,tr|C9JYQ9|C9JYQ9_HUMAN" 3 1408.7198 1.38 79942 10038 2 1408.72109 705.3672 60S ribosomal protein L22-like 1 OS=Homo sapiens OX=9606 GN=RPL22L1 PE=1 SV=2 4.68 2022.4 - 308638 - - - 0.9093 - 2.205 0.442 - 528.8 1 2 1 0.0013 12 0 0 0 2.48E+06 1.80E+06 - - - 4.3857 0.9695 221125_WJC_METTL3_EV_vs_WT_F06.10039.10039.4 813 1/144 R.C[160.03]VSPDTC[160.03]HC[160.03]EPGWGGPDC[160.03]SSGC[160.03]DSD.H "sp|A6BM72|MEG11_HUMAN,tr|A0A0G2JLW8|A0A0G2JLW8_HUMAN,tr|A0A0G2JN40|A0A0G2JN40_HUMAN,tr|A0A0A0MS64|A0A0A0MS64_HUMAN" 4 2797.9408 - 79943 10039 4 2797.928021 700.4925 Multiple epidermal growth factor-like domains protein 11 OS=Homo sapiens OX=9606 GN=MEGF11 PE=1 SV=3 3.88 2022.6 - 207343 - - - -4.5494 - 0.215 0.618 - 0.3 1 1 0 -0.0127 25 0 0 0 - - - - - 4.1126 1 221125_WJC_METTL3_EV_vs_WT_F06.10043.10043.3 7.13E-05 14/44 K.TDAASKPFAEVR.L "sp|Q13427|PPIG_HUMAN,tr|A0A7I2V629|A0A7I2V629_HUMAN,tr|C9JM79|C9JM79_HUMAN,tr|E9PG73|E9PG73_HUMAN,tr|C9JN15|C9JN15_HUMAN,tr|A0A7I2V4F2|A0A7I2V4F2_HUMAN,tr|A0A7I2V5Q5|A0A7I2V5Q5_HUMAN" 7 1290.6568 1.05 79945 10043 3 1290.657575 431.2262 Peptidyl-prolyl cis-trans isomerase G OS=Homo sapiens OX=9606 GN=PPIG PE=1 SV=2 5.74 2023 - 7.06E+06 - - - 0.5888 - 2.764 0.511 - 259.9 1 2 0 0.0008 12 0 0 0 9.66E+07 9.23E+07 - - - 7.055 0.7648 221125_WJC_METTL3_EV_vs_WT_F06.10044.10044.3 0.612 Sep-48 R.QAVPGRPGPFPSK.Q "sp|Q9Y520|PRC2C_HUMAN,tr|A0A0A0MS30|A0A0A0MS30_HUMAN,tr|E7EPN9|E7EPN9_HUMAN" 3 1336.7252 1.14 79946 10044 3 1336.725552 446.5823 Protein PRRC2C OS=Homo sapiens OX=9606 GN=PRRC2C PE=1 SV=4 11 2023 - 2.02E+06 - - - 0.2865 - 1.521 0.045 - 93 4 2 0 0.0004 13 0 0 0 3.00E+08 2.62E+08 - - - -0.1 1 221125_WJC_METTL3_EV_vs_WT_F06.10047.10047.2 6.91E-06 13/26 R.WDQTADQTPGATPK.K sp|O75533|SF3B1_HUMAN 1 1514.7001 1.25 79949 10047 2 1514.698633 758.3573 Splicing factor 3B subunit 1 OS=Homo sapiens OX=9606 GN=SF3B1 PE=1 SV=3 4.21 2023.3 - 761326 - - - -0.9929 - 2.77 0.588 - 547.6 1 2 0 -0.0015 14 0 0 0 5.50E+07 4.40E+07 - - - 5.9402 0.9992 221125_WJC_METTL3_EV_vs_WT_F06.10049.10049.2 0.0464 24-Nov K.SEHPGLSIGDTAK[136.11].K "sp|P26583|HMGB2_HUMAN,tr|D6R9A6|D6R9A6_HUMAN" 2 1318.6608 0.25 79951 10049 2 1318.663803 660.3377 High mobility group protein B2 OS=Homo sapiens OX=9606 GN=HMGB2 PE=1 SV=2 5.3 2023.6 - 705183 - - - 2.2439 - 2.197 0.341 - 253.1 1 2 0 0.003 13 0 0 0 1.94E+06 7.83E+06 - - - 3.5788 1 221125_WJC_METTL3_EV_vs_WT_F06.10050.10050.2 1.44E-06 16/26 R.WDQTADQTPGATPK[136.11].K sp|O75533|SF3B1_HUMAN 1 1522.7143 1.23 79952 10050 2 1522.711615 762.3644 Splicing factor 3B subunit 1 OS=Homo sapiens OX=9606 GN=SF3B1 PE=1 SV=3 4.21 2023.7 - 573173 - - - -1.7876 - 3.197 0.609 - 935.8 1 2 0 -0.0027 14 0 0 0 5.50E+07 4.47E+07 - - - 6.4547 0.8352 221125_WJC_METTL3_EV_vs_WT_F06.10059.10059.2 0.136 24-Jul S.GGLGGQEEEEEQR[166.11].W "sp|Q9C086|IN80B_HUMAN,tr|J3KQ70|J3KQ70_HUMAN,tr|B8ZZ93|B8ZZ93_HUMAN,tr|B8ZZH7|B8ZZH7_HUMAN,tr|F8WCL7|F8WCL7_HUMAN,tr|C9JKY0|C9JKY0_HUMAN" 6 1426.62 0.001 79959 10059 2 1426.621296 714.3173 INO80 complex subunit B OS=Homo sapiens OX=9606 GN=INO80B PE=1 SV=2 3.98 2024.8 - 2.62E+06 - - - 0.919 - 1.202 0.282 - 90.1 1 1 0 0.0013 13 0 0 0 0.00E+00 5.75E+07 - - - 1.5956 0.9647 221125_WJC_METTL3_EV_vs_WT_F06.10061.10061.2 0.0958 14-Jul L.KWLDSDAR.N "sp|P34913|HYES_HUMAN,tr|E5RFU2|E5RFU2_HUMAN,tr|E5RFH6|E5RFH6_HUMAN" 3 989.493 999 79961 10061 2 989.49313 495.7538 Bifunctional epoxide hydrolase 2 OS=Homo sapiens OX=9606 GN=EPHX2 PE=1 SV=2 5.96 2024.9 - 1.03E+07 - - - 0.0869 - 1.352 0.39 - 295.2 1 1 0 0.0001 8 0 0 0 5.15E+10 0.00E+00 - - - 2.8311 0.9994 221125_WJC_METTL3_EV_vs_WT_F06.10062.10062.3 0.00673 Oct-32 R.QFC[160.03]TGEFRK.D "sp|O43447|PPIH_HUMAN,tr|A0A7I2V2H6|A0A7I2V2H6_HUMAN,tr|A0A7I2V343|A0A7I2V343_HUMAN,tr|A0A7I2YQS4|A0A7I2YQS4_HUMAN,tr|C9JQD4|C9JQD4_HUMAN" 5 1171.5444 1.95 79962 10062 3 1171.544528 391.5221 Peptidyl-prolyl cis-trans isomerase H OS=Homo sapiens OX=9606 GN=PPIH PE=1 SV=1 8.22 2024.9 - 2.09E+06 - - - 0.0854 - 1.71 0.322 - 122.5 1 2 0 0.0001 9 0 0 0 1.89E+07 9.68E+06 - - - 3.7468 0.973 221125_WJC_METTL3_EV_vs_WT_F06.10065.10065.2 0.0195 20-Oct K.VQDQDLPNTPH.S sp|Q08554|DSC1_HUMAN 1 1262.5891 - 79964 10065 2 1262.591184 632.3018 Desmocollin-1 OS=Homo sapiens OX=9606 GN=DSC1 PE=1 SV=2 4.2 2025.3 - 1.07E+06 - - - 1.6276 - 1.956 0.398 - 371 1 1 0 0.0021 11 0 0 0 - - - - - 3.7949 0.9963 221125_WJC_METTL3_EV_vs_WT_F06.10066.10066.3 0.162 Nov-44 K.AYPLADAHLTKK.L "sp|P55769|NH2L1_HUMAN,tr|B1AHD1|B1AHD1_HUMAN,tr|A0A3B3IUA2|A0A3B3IUA2_HUMAN" 3 1326.7296 1.64 79965 10066 3 1326.728531 443.2505 NHP2-like protein 1 OS=Homo sapiens OX=9606 GN=SNU13 PE=1 SV=3 8.55 2025.4 - 833251 - - - -0.7952 - 1.77 0.206 - 111.8 1 2 0 -0.0011 12 0 0 0 6.94E+07 4.24E+07 - - - 2.4191 0.9999 221125_WJC_METTL3_EV_vs_WT_F06.10070.10070.2 6.81E-05 18-Nov K.TC[160.03]YIC[160.03]DEQGR[166.11].E "sp|P55197|AF10_HUMAN,tr|A0A494C0R2|A0A494C0R2_HUMAN,tr|A0A494C038|A0A494C038_HUMAN" 3 1310.5259 2.76 79969 10070 2 1310.526725 656.2702 Protein AF-10 OS=Homo sapiens OX=9606 GN=MLLT10 PE=1 SV=2 4.37 2025.8 - 502876 - - - 0.6364 - 1.923 0.539 - 537.1 1 2 0 0.0008 10 0 0 0 1.98E+07 7.18E+06 - - - 4.847 0.9998 221125_WJC_METTL3_EV_vs_WT_F06.10077.10077.2 0.000116 18-Oct R.DNQLSEVANK[136.11].F "sp|Q14978|NOLC1_HUMAN,tr|S4R341|S4R341_HUMAN,tr|S4R402|S4R402_HUMAN,tr|A0A0A0MRM9|A0A0A0MRM9_HUMAN,tr|S4R349|S4R349_HUMAN" 5 1124.5553 2.17 79974 10077 2 1124.554536 563.2849 Nucleolar and coiled-body phosphoprotein 1 OS=Homo sapiens OX=9606 GN=NOLC1 PE=1 SV=2 4.37 2026.8 - 2.17E+07 - - - -0.6945 - 1.942 0.46 - 310 1 2 0 -0.0008 10 0 0 0 1.09E+09 5.00E+08 - - - 4.291 0.8334 221125_WJC_METTL3_EV_vs_WT_F06.10079.10079.2 0.789 12-Jun N.KIDSEGR.S "sp|O75762|TRPA1_HUMAN,tr|H0YAW0|H0YAW0_HUMAN" 2 803.4137 9519.76 79976 10079 2 803.413351 402.7141 Transient receptor potential cation channel subfamily A member 1 OS=Homo sapiens OX=9606 GN=TRPA1 PE=1 SV=3 6.07 2026.9 - 1.25E+07 - - - -0.473 - 1.415 0.173 - 169 1 1 0 -0.0004 7 0 0 0 4.24E+09 4.45E+05 - - - 1.4186 1 221125_WJC_METTL3_EV_vs_WT_F06.10082.10082.3 0.00158 13/44 K.VTWDGHSGSMAR.T "sp|Q15459|SF3A1_HUMAN,tr|H7C1L2|H7C1L2_HUMAN" 2 1302.5775 1.08 79979 10082 3 1302.578061 435.1998 Splicing factor 3A subunit 1 OS=Homo sapiens OX=9606 GN=SF3A1 PE=1 SV=1 6.71 2027 - 2.86E+06 - - - 0.4161 - 2.67 0.5 - 350.6 1 2 0 0.0005 12 0 0 0 2.64E+07 2.45E+07 - - - 6.8365 0.9996 221125_WJC_METTL3_EV_vs_WT_F06.10083.10083.2 4.03E-05 13/20 R.NIEELQQQNQR[166.11].L sp|P12270|TPR_HUMAN 1 1408.6934 3.66 79980 10083 2 1408.689384 705.354 Nucleoprotein TPR OS=Homo sapiens OX=9606 GN=TPR PE=1 SV=3 4.53 2027.1 - 1.21E+06 - - - -2.8686 - 2.604 0.488 - 614.5 1 2 0 -0.004 11 0 0 0 1.52E+08 4.16E+07 - - - 5.2331 0.9998 221125_WJC_METTL3_EV_vs_WT_F06.10084.10084.3 0.000206 Dec-40 R.NIEELQQQNQR.L sp|P12270|TPR_HUMAN 1 1398.6852 2.02 79981 10084 3 1398.687971 467.2357 Nucleoprotein TPR OS=Homo sapiens OX=9606 GN=TPR PE=1 SV=3 4.53 2027.3 - 1.19E+06 - - - 2.0133 - 2.39 0.365 - 289.4 1 2 0 0.0028 11 0 0 0 4.32E+07 2.14E+07 - - - 5.0838 0.9994 221125_WJC_METTL3_EV_vs_WT_F06.10086.10086.3 0.0356 Dec-36 K.RQELEAELAK.V sp|Q15149|PLEC_HUMAN 1 1185.6354 1.33 79983 10086 3 1185.634537 396.2191 Plectin OS=Homo sapiens OX=9606 GN=PLEC PE=1 SV=3 4.79 2027.5 - 1.16E+06 - - - -0.6866 - 2.268 0.242 - 213 1 2 0 -0.0008 10 0 0 0 1.42E+08 1.07E+08 - - - 3.6294 0.8498 221125_WJC_METTL3_EV_vs_WT_F06.10089.10089.3 0.0363 Sep-44 V.LKPNKPLILANR.V "sp|Q96BP2|CHCH1_HUMAN,tr|A6NJX6|A6NJX6_HUMAN" 2 1375.8664 2.3 79986 10089 3 1375.866337 459.6294 Coiled-coil-helix-coiled-coil-helix domain-containing protein 1 OS=Homo sapiens OX=9606 GN=CHCHD1 PE=1 SV=1 11.17 2027.9 - 1.03E+06 - - - -0.0124 - 1.541 0.288 - 58.4 1 1 0 0 12 0 0 0 9.65E+06 4.20E+06 - - - 2.9495 0.9998 221125_WJC_METTL3_EV_vs_WT_F06.10090.10090.2 0.000269 18-Oct R.KVEITTETIK.L "sp|Q92643|GPI8_HUMAN,tr|B1AK81|B1AK81_HUMAN,tr|A6NEM5|A6NEM5_HUMAN" 3 1160.6653 1.38 79987 10090 2 1160.665167 581.3399 GPI-anchor transamidase OS=Homo sapiens OX=9606 GN=PIGK PE=1 SV=2 6.14 2028 - 339592 - - - -0.0758 - 1.842 0.469 - 299.6 1 2 0 -0.0001 10 0 0 0 2.68E+06 1.95E+06 - - - 4.2101 0.9999 221125_WJC_METTL3_EV_vs_WT_F06.10095.10095.3 0.000144 Oct-44 R.VVDSMEDEVQRR.L "sp|Q9Y285|SYFA_HUMAN,tr|K7ER16|K7ER16_HUMAN,tr|K7ER00|K7ER00_HUMAN" 3 1461.6882 2.05 79990 10095 3 1461.687193 488.2367 Phenylalanine--tRNA ligase alpha subunit OS=Homo sapiens OX=9606 GN=FARSA PE=1 SV=3 4.32 2028.6 - 3.54E+06 - - - -0.6835 - 1.938 0.433 - 178.3 1 2 0 -0.001 12 0 0 0 3.58E+07 1.74E+07 - - - 5.2013 0.982 221125_WJC_METTL3_EV_vs_WT_F06.10097.10097.2 0.0163 15/18 S.RSLYGLGGSK.R "sp|P48668|K2C6C_HUMAN,sp|P04259|K2C6B_HUMAN,sp|P02538|K2C6A_HUMAN" 3 1036.5665 6.16 79992 10097 2 1036.565949 519.2905 "Keratin, type II cytoskeletal 6C OS=Homo sapiens OX=9606 GN=KRT6C PE=1 SV=3" 9.99 2028.7 - 3.60E+06 - - - -0.573 - 2.511 0.27 - 727.3 1 1 0 -0.0006 10 0 0 0 4.45E+07 7.23E+06 - - - 3.6049 0.9995 221125_WJC_METTL3_EV_vs_WT_F06.10098.10098.3 0.00037 Sep-52 K.EVTGVHSMEDNGIK.H "sp|O15409|FOXP2_HUMAN,tr|Q0PRL4|Q0PRL4_HUMAN,tr|Q8N6B5|Q8N6B5_HUMAN,tr|A8MTU2|A8MTU2_HUMAN,tr|A0A0U1RQE0|A0A0U1RQE0_HUMAN,tr|A0A0U1RQR8|A0A0U1RQR8_HUMAN,tr|A8MUV4|A8MUV4_HUMAN,tr|A0A0U1RQM2|A0A0U1RQM2_HUMAN,tr|A0A0U1RQY3|A0A0U1RQY3_HUMAN,tr|A0A0U1RQE6|A0A0U1RQE6_HUMAN" 10 1514.7035 3.64 79993 10098 3 1514.699992 505.9084 Forkhead box protein P2 OS=Homo sapiens OX=9606 GN=FOXP2 PE=1 SV=2 4.65 2028.8 - 1.90E+06 - - - -2.3206 - 1.864 0.387 - 79.2 1 2 0 -0.0035 14 0 0 0 2.43E+07 6.67E+06 - - - 4.5086 0.9993 221125_WJC_METTL3_EV_vs_WT_F06.10100.10100.3 0.00157 Oct-48 K.SEHPGLSIGDTAK[136.11].K "sp|P26583|HMGB2_HUMAN,tr|D6R9A6|D6R9A6_HUMAN" 2 1318.6608 0.17 79995 10100 3 1318.663145 440.5609 High mobility group protein B2 OS=Homo sapiens OX=9606 GN=HMGB2 PE=1 SV=2 5.3 2028.9 - 1.65E+06 - - - 1.745 - 1.963 0.322 - 155 1 2 0 0.0023 13 0 0 0 7.02E+06 4.12E+07 - - - 3.958 1 221125_WJC_METTL3_EV_vs_WT_F06.10103.10103.2 3.22E-06 14/28 K.VEQLGAEGNVEESQK.V "sp|Q9Y383|LC7L2_HUMAN,tr|A0A0A6YYJ8|A0A0A6YYJ8_HUMAN" 2 1615.7689 2.96 79998 10103 2 1615.769393 808.8917 Putative RNA-binding protein Luc7-like 2 OS=Homo sapiens OX=9606 GN=LUC7L2 PE=1 SV=2 4.09 2029.3 - 867348 - - - 0.2779 - 2.747 0.609 - 657.3 1 2 0 0.0004 15 0 0 0 7.51E+07 2.54E+07 - - - 6.0233 0.9987 221125_WJC_METTL3_EV_vs_WT_F06.10104.10104.2 0.0886 24-Dec R.QAVPGRPGPFPSK.Q "sp|Q9Y520|PRC2C_HUMAN,tr|A0A0A0MS30|A0A0A0MS30_HUMAN,tr|E7EPN9|E7EPN9_HUMAN" 3 1336.7252 1.47 79999 10104 2 1336.728076 669.3699 Protein PRRC2C OS=Homo sapiens OX=9606 GN=PRRC2C PE=1 SV=4 11 2029.4 - 606838 - - - 2.1747 - 1.91 0.311 - 370 1 2 0 0.0029 13 0 0 0 2.80E+07 1.90E+07 - - - 2.9979 0.9999 221125_WJC_METTL3_EV_vs_WT_F06.10106.10106.2 0.00398 20-Nov R.NIEELQQQNQR.L sp|P12270|TPR_HUMAN 1 1398.6852 3.67 80000 10106 2 1398.684293 700.3499 Nucleoprotein TPR OS=Homo sapiens OX=9606 GN=TPR PE=1 SV=3 4.53 2029.6 - 1.21E+07 - - - -0.6163 - 2.439 0.461 - 382.2 1 2 0 -0.0009 11 0 0 0 1.53E+08 4.16E+07 - - - 4.8576 0.9988 221125_WJC_METTL3_EV_vs_WT_F06.10108.10108.2 0.000195 20-Oct K.SNFSNSADDIK.S sp|P45973|CBX5_HUMAN 1 1196.5309 0.9 80001 10108 2 1196.526052 599.2727 Chromobox protein homolog 5 OS=Homo sapiens OX=9606 GN=CBX5 PE=1 SV=1 4.21 2029.8 - 4.32E+06 - - - -4.0902 - 1.904 0.562 - 322.1 1 2 0 -0.0049 11 0 0 0 5.11E+07 5.69E+07 - - - 4.9325 0.9997 221125_WJC_METTL3_EV_vs_WT_F06.10111.10111.2 1.05E-06 17/18 R.SSFSHYSGLK.H sp|Q8NC51|PAIRB_HUMAN 1 1111.5298 0.59 80004 10111 2 1111.526994 556.7722 Plasminogen activator inhibitor 1 RNA-binding protein OS=Homo sapiens OX=9606 GN=SERBP1 PE=1 SV=2 8.33 2030 - 3.27E+06 - - - -2.546 - 2.534 0.545 - 949 1 2 0 -0.0028 10 0 0 0 1.96E+08 3.31E+08 - - - 5.6608 0.9989 221125_WJC_METTL3_EV_vs_WT_F06.10112.10112.3 0.0161 Aug-52 K.LLYNR[166.11]PGTVSSLK[136.11]K[136.11].N "sp|P35659|DEK_HUMAN,tr|H0Y8X0|H0Y8X0_HUMAN,tr|H0Y993|H0Y993_HUMAN,tr|A0A494C028|A0A494C028_HUMAN,tr|D6RDA2|D6RDA2_HUMAN,tr|B4DFG0|B4DFG0_HUMAN" 6 1600.9511 0.69 80005 10112 3 1600.950653 534.6576 Protein DEK OS=Homo sapiens OX=9606 GN=DEK PE=1 SV=1 10.29 2030.2 - 758815 - - - -0.2773 - 1.663 0.298 - 59.8 1 2 0 -0.0004 14 0 0 0 7.31E+07 1.05E+08 - - - 3.214 0.9997 221125_WJC_METTL3_EV_vs_WT_F06.10113.10113.2 0.000743 22-Sep R.NPELPNAAQAQK.E sp|O60264|SMCA5_HUMAN 1 1279.6521 0.94 80006 10113 2 1279.650208 640.8333 SWI\SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A member 5 OS=Homo sapiens OX=9606 GN=SMARCA5 PE=1 SV=1 6 2030.3 - 709895 - - - -1.4504 - 1.93 0.436 - 190.4 1 2 0 -0.0019 12 0 0 0 1.24E+07 1.32E+07 - - - 3.9908 1 221125_WJC_METTL3_EV_vs_WT_F06.10116.10116.2 2.33E-07 18-Nov R.DNQLSEVANK.F "sp|Q14978|NOLC1_HUMAN,tr|S4R341|S4R341_HUMAN,tr|S4R402|S4R402_HUMAN,tr|A0A0A0MRM9|A0A0A0MRM9_HUMAN,tr|S4R349|S4R349_HUMAN" 5 1116.5411 2.17 80007 10116 2 1116.539133 559.2778 Nucleolar and coiled-body phosphoprotein 1 OS=Homo sapiens OX=9606 GN=NOLC1 PE=1 SV=2 4.37 2030.7 - 6.60E+07 - - - -1.7769 - 2.495 0.612 - 702.7 1 2 0 -0.002 10 0 0 0 1.09E+09 5.00E+08 - - - 6.1127 0.9357 221125_WJC_METTL3_EV_vs_WT_F06.10118.10118.2 2.94E-06 20-Nov K.SKAEAESLYQS.K sp|P04264|K2C1_HUMAN 1 1211.567 20.6 80009 10118 2 1211.566018 606.7908 "Keratin, type II cytoskeletal 1 OS=Homo sapiens OX=9606 GN=KRT1 PE=1 SV=6" 4.53 2030.8 - 5.23E+06 - - - -0.808 - 2.072 0.597 - 252.6 1 1 1 -0.001 11 0 0 0 1.11E+08 5.38E+06 - - - 5.4209 0.9984 221125_WJC_METTL3_EV_vs_WT_F06.10131.10131.2 0.00247 16-Nov K.QLTQLINK[136.11]K[136.11].E "sp|Q15643|TRIPB_HUMAN,tr|H0YJ97|H0YJ97_HUMAN" 2 1100.6888 1.13 80016 10131 2 1100.685252 551.3517 Thyroid receptor-interacting protein 11 OS=Homo sapiens OX=9606 GN=TRIP11 PE=1 SV=3 10 2032.4 - 1.69E+06 - - - -3.2634 - 1.9 0.362 - 335.1 1 2 0 -0.0036 9 0 0 0 4.00E+07 3.53E+07 - - - 3.5705 0.9999 221125_WJC_METTL3_EV_vs_WT_F06.10134.10134.3 0.00749 13/40 R.QLTAHLQDVNR[166.11].E "sp|Q14203|DCTN1_HUMAN,tr|A0A804CDA6|A0A804CDA6_HUMAN,tr|E7EX90|E7EX90_HUMAN,tr|A0A7P0Z4C3|A0A7P0Z4C3_HUMAN,tr|Q6AWB1|Q6AWB1_HUMAN" 5 1303.6872 1.84 80018 10134 3 1303.687079 435.5697 Dynactin subunit 1 OS=Homo sapiens OX=9606 GN=DCTN1 PE=1 SV=3 6.74 2032.6 - 3.20E+06 - - - -0.1066 - 2.348 0.349 - 305.8 1 2 0 -0.0001 11 0 0 0 7.49E+08 4.07E+08 - - - 4.8558 0.8734 221125_WJC_METTL3_EV_vs_WT_F06.10135.10135.2 0.00354 18-Sep K.SKELTTEIDN.N "sp|P13645|K1C10_HUMAN,tr|A0A1B0GVI3|A0A1B0GVI3_HUMAN" 2 1148.5561 282.05 80019 10135 2 1148.556096 575.2853 "Keratin, type I cytoskeletal 10 OS=Homo sapiens OX=9606 GN=KRT10 PE=1 SV=6" 4.14 2032.7 - 1.67E+06 - - - -0.0017 - 1.963 0.414 - 247.9 1 1 1 0 10 0 0 0 4.00E+07 1.42E+05 - - - 3.9815 0.9998 221125_WJC_METTL3_EV_vs_WT_F06.10138.10138.2 4.62E-06 28-Nov R.INPPSSGGTSSSPIK.A "sp|P14859|PO2F1_HUMAN,tr|A0A0C4DG88|A0A0C4DG88_HUMAN,tr|A0A0A0MT46|A0A0A0MT46_HUMAN" 3 1427.7256 2.06 80021 10138 2 1427.72717 714.8701 "POU domain, class 2, transcription factor 1 OS=Homo sapiens OX=9606 GN=POU2F1 PE=1 SV=2" 8.75 2033.1 - 4.31E+06 - - - 1.0835 - 2.346 0.488 - 151.9 1 2 0 0.0015 15 0 0 0 2.16E+08 1.05E+08 - - - 4.7413 0.9835 221125_WJC_METTL3_EV_vs_WT_F06.10141.10141.2 0.0371 16-Nov K.QK[136.11]EVEQLIK[136.11].K "sp|P25789|PSA4_HUMAN,tr|H0YN18|H0YN18_HUMAN" 2 1129.6678 1.57 80023 10141 2 1129.668618 565.8412 Proteasome subunit alpha type-4 OS=Homo sapiens OX=9606 GN=PSMA4 PE=1 SV=1 6.14 2033.4 - 2.96E+06 - - - 0.7471 - 1.473 0.272 - 125.4 1 2 1 0.0008 9 0 0 0 1.04E+08 6.60E+07 - - - 2.1702 1 221125_WJC_METTL3_EV_vs_WT_F06.10142.10142.2 6.19E-07 18/26 K.SVTEQGAELSNEER[166.11].N "sp|P63104|1433Z_HUMAN,tr|E7EX29|E7EX29_HUMAN,tr|E5RIR4|E5RIR4_HUMAN,tr|E7EVZ2|E7EVZ2_HUMAN,tr|E5RGE1|E5RGE1_HUMAN,tr|E9PD24|E9PD24_HUMAN,tr|E7ESK7|E7ESK7_HUMAN" 7 1557.7146 1.31 80024 10142 2 1557.70995 779.8646 14-3-3 protein zeta\delta OS=Homo sapiens OX=9606 GN=YWHAZ PE=1 SV=1 4.09 2033.6 - 1.35E+06 - - - -2.9941 - 3.611 0.61 - 1249.2 1 2 0 -0.0047 14 0 0 0 3.73E+08 2.85E+08 - - - 6.7671 0.9997 221125_WJC_METTL3_EV_vs_WT_F06.10147.10147.3 0.00114 14/36 K.LEENIDNIKR.N "sp|Q92878|RAD50_HUMAN,tr|A0A494BZX8|A0A494BZX8_HUMAN,tr|A0A1W2PQ90|A0A1W2PQ90_HUMAN" 3 1242.6568 1.05 80027 10147 3 1242.654416 415.2262 DNA repair protein RAD50 OS=Homo sapiens OX=9606 GN=RAD50 PE=1 SV=1 4.68 2034.2 - 2.67E+06 - - - -1.9305 - 2.129 0.347 - 239.5 1 2 0 -0.0024 10 0 0 0 4.30E+07 4.08E+07 - - - 4.6149 0.9895 221125_WJC_METTL3_EV_vs_WT_F06.10148.10148.3 0.00145 13/36 R.QAVDVSPLR[166.11]R[166.11].V "sp|P46782|RS5_HUMAN,tr|M0QZN2|M0QZN2_HUMAN,tr|M0R0F0|M0R0F0_HUMAN,tr|M0R0R2|M0R0R2_HUMAN" 4 1159.6576 0.81 80028 10148 3 1159.657302 387.5598 40S ribosomal protein S5 OS=Homo sapiens OX=9606 GN=RPS5 PE=1 SV=4 9.6 2034.2 - 3.09E+06 - - - -0.2958 - 2.158 0.089 - 331.6 1 2 0 -0.0003 10 0 0 0 3.59E+08 4.42E+08 - - - 1.7785 1 221125_WJC_METTL3_EV_vs_WT_F06.10150.10150.2 1.12E-07 19/26 K.SVTEQGAELSNEER.N "sp|P63104|1433Z_HUMAN,tr|E7EX29|E7EX29_HUMAN,tr|E5RIR4|E5RIR4_HUMAN,tr|E7EVZ2|E7EVZ2_HUMAN,tr|E5RGE1|E5RGE1_HUMAN,tr|E9PD24|E9PD24_HUMAN,tr|E7ESK7|E7ESK7_HUMAN" 7 1547.7063 1.31 80030 10150 2 1547.70337 774.8604 14-3-3 protein zeta\delta OS=Homo sapiens OX=9606 GN=YWHAZ PE=1 SV=1 4.09 2034.4 - 2.73E+06 - - - -1.9216 - 3.663 0.614 - 1399.6 1 2 0 -0.003 14 0 0 0 3.73E+08 2.85E+08 - - - 6.833 0.9998 221125_WJC_METTL3_EV_vs_WT_F06.10151.10151.2 4.22E-05 15/20 R.QLTAHLQDVNR[166.11].E "sp|Q14203|DCTN1_HUMAN,tr|A0A804CDA6|A0A804CDA6_HUMAN,tr|E7EX90|E7EX90_HUMAN,tr|A0A7P0Z4C3|A0A7P0Z4C3_HUMAN,tr|Q6AWB1|Q6AWB1_HUMAN" 5 1303.6872 4.85 80031 10151 2 1303.685968 652.8509 Dynactin subunit 1 OS=Homo sapiens OX=9606 GN=DCTN1 PE=1 SV=3 6.74 2034.6 - 1.68E+06 - - - -0.9588 - 2.435 0.444 - 1226.1 1 2 0 -0.0013 11 0 0 0 3.95E+08 8.13E+07 - - - 4.7275 0.9282 221125_WJC_METTL3_EV_vs_WT_F06.10155.10155.3 0.136 14/36 R.TNRPPLSLSR.M "sp|Q07020|RL18_HUMAN,tr|J3QQ67|J3QQ67_HUMAN,tr|F8VUA6|F8VUA6_HUMAN,tr|G3V203|G3V203_HUMAN,tr|F8VYV2|F8VYV2_HUMAN,tr|H0YHA7|H0YHA7_HUMAN,tr|A0A075B7A0|A0A075B7A0_HUMAN" 7 1139.6411 0.81 80033 10155 3 1139.640082 380.8876 60S ribosomal protein L18 OS=Homo sapiens OX=9606 GN=RPL18 PE=1 SV=2 12 2035.1 - 2.24E+06 - - - -0.8977 - 1.956 0.013 - 275.2 1 2 0 -0.001 10 0 0 0 3.60E+08 4.42E+08 - - - 0.644 0.9998 221125_WJC_METTL3_EV_vs_WT_F06.10156.10156.2 0.0102 18-Dec K.KGEDVLGSVR.R "sp|P56192|SYMC_HUMAN,tr|F5H2V6|F5H2V6_HUMAN" 2 1058.572 0.89 80034 10156 2 1058.572086 530.2933 "Methionine--tRNA ligase, cytoplasmic OS=Homo sapiens OX=9606 GN=MARS1 PE=1 SV=2" 6.07 2035.2 - 939453 - - - 0.0595 - 2.299 0.365 - 478.4 1 2 0 0.0001 10 0 0 0 2.33E+07 2.60E+07 - - - 4.0606 0.9999 221125_WJC_METTL3_EV_vs_WT_F06.10160.10160.2 6.54E-09 14/28 R.INPPSSGGTSSSPIK[136.11].A "sp|P14859|PO2F1_HUMAN,tr|A0A0C4DG88|A0A0C4DG88_HUMAN,tr|A0A0A0MT46|A0A0A0MT46_HUMAN" 3 1435.7398 2.06 80037 10160 2 1435.738894 718.8772 "POU domain, class 2, transcription factor 1 OS=Homo sapiens OX=9606 GN=POU2F1 PE=1 SV=2" 8.75 2035.7 - 1.97E+06 - - - -0.6471 - 2.518 0.581 - 261.9 1 2 0 -0.0009 15 0 0 0 2.10E+08 1.02E+08 - - - 5.6024 0.9989 221125_WJC_METTL3_EV_vs_WT_F06.10162.10162.3 0.00943 Nov-52 K.LLYNRPGTVSSLKK.N "sp|P35659|DEK_HUMAN,tr|H0Y8X0|H0Y8X0_HUMAN,tr|H0Y993|H0Y993_HUMAN,tr|A0A494C028|A0A494C028_HUMAN,tr|D6RDA2|D6RDA2_HUMAN,tr|B4DFG0|B4DFG0_HUMAN" 6 1574.9144 0.69 80038 10162 3 1574.914759 525.9788 Protein DEK OS=Homo sapiens OX=9606 GN=DEK PE=1 SV=1 10.29 2035.9 - 4.95E+06 - - - 0.2108 - 1.698 0.318 - 90.7 3 2 0 0.0003 14 0 0 0 7.31E+07 1.05E+08 - - - 3.2715 0.9935 221125_WJC_METTL3_EV_vs_WT_F06.10163.10163.3 0.00619 Oct-44 R.EILQDKDGLNQR.Y "sp|Q9H6R4|NOL6_HUMAN,tr|A0A0A0MRW6|A0A0A0MRW6_HUMAN" 2 1427.7369 1.42 80039 10163 3 1427.734635 476.9196 Nucleolar protein 6 OS=Homo sapiens OX=9606 GN=NOL6 PE=1 SV=2 4.56 2036 - 2.70E+06 - - - -1.5556 - 2.039 0.247 - 169.8 1 2 1 -0.0022 12 0 0 0 7.02E+07 4.96E+07 - - - 3.268 0.9996 221125_WJC_METTL3_EV_vs_WT_F06.10167.10167.3 0.000406 17/52 K.SVTEQGAELSNEER.N "sp|P63104|1433Z_HUMAN,tr|E7EX29|E7EX29_HUMAN,tr|E5RIR4|E5RIR4_HUMAN,tr|E7EVZ2|E7EVZ2_HUMAN,tr|E5RGE1|E5RGE1_HUMAN,tr|E9PD24|E9PD24_HUMAN,tr|E7ESK7|E7ESK7_HUMAN" 7 1547.7063 1.09 80041 10167 3 1547.702976 516.9094 14-3-3 protein zeta\delta OS=Homo sapiens OX=9606 GN=YWHAZ PE=1 SV=1 4.09 2036.5 - 2.44E+06 - - - -2.1761 - 2.378 0.329 - 377.9 1 2 0 -0.0034 14 0 0 0 6.27E+07 5.73E+07 - - - 4.5092 0.997 221125_WJC_METTL3_EV_vs_WT_F06.10168.10168.2 0.00894 13/16 R.ERLELC[160.03]DER.V sp|P07919|QCR6_HUMAN 1 1218.5663 1.02 80042 10168 2 1218.567595 610.2904 "Cytochrome b-c1 complex subunit 6, mitochondrial OS=Homo sapiens OX=9606 GN=UQCRH PE=1 SV=2" 4.41 2036.6 - 1.15E+06 - - - 1.0742 - 2.209 0.377 - 631.1 1 2 1 0.0013 9 0 0 0 2.16E+07 2.12E+07 - - - 4.118 0.9973 221125_WJC_METTL3_EV_vs_WT_F06.10169.10169.2 3.21E-05 20-Nov K.TIIQNPTDQQK.K "sp|Q9UQ80|PA2G4_HUMAN,tr|F8VR77|F8VR77_HUMAN" 2 1284.6674 0.12 80043 10169 2 1284.672745 643.341 Proliferation-associated protein 2G4 OS=Homo sapiens OX=9606 GN=PA2G4 PE=1 SV=3 5.5 2036.7 - 1.53E+06 - - - 4.1762 - 1.987 0.392 - 307.4 1 2 0 0.0054 11 0 0 0 5.42E+07 4.57E+08 - - - 3.7921 0.9923 221125_WJC_METTL3_EV_vs_WT_F06.10170.10170.2 0.00076 18-Dec K.VPQIEVETHK[136.11].V "sp|Q14204|DYHC1_HUMAN,tr|A0A7P0T8N2|A0A7P0T8N2_HUMAN,tr|A0A7P0T9C4|A0A7P0T9C4_HUMAN,tr|A0A7P0TBJ7|A0A7P0TBJ7_HUMAN,tr|A0A804HHY6|A0A804HHY6_HUMAN,tr|A0A7P0T9K2|A0A7P0T9K2_HUMAN,tr|A0A7P0TB64|A0A7P0TB64_HUMAN,tr|A0A2R8Y706|A0A2R8Y706_HUMAN,tr|A0A7P0T916|A0A7P0T916_HUMAN,tr|A0A7P0TB75|A0A7P0TB75_HUMAN,tr|A0A7P0T8W5|A0A7P0T8W5_HUMAN,tr|A0A7P0TAF3|A0A7P0TAF3_HUMAN,tr|A0A7P0T9F1|A0A7P0T9F1_HUMAN,tr|A0A7P0TAW9|A0A7P0TAW9_HUMAN,tr|A0A2R8YGC7|A0A2R8YGC7_HUMAN,tr|A0A7P0TA13|A0A7P0TA13_HUMAN,tr|A0A7P0TAV5|A0A7P0TAV5_HUMAN,tr|A0A7P0T7V5|A0A7P0T7V5_HUMAN,tr|A0A7P0T9R4|A0A7P0T9R4_HUMAN,tr|A0A2R8Y5T0|A0A2R8Y5T0_HUMAN,tr|A0A7P0T990|A0A7P0T990_HUMAN,tr|A0A7P0T942|A0A7P0T942_HUMAN,tr|A0A2R8YFZ7|A0A2R8YFZ7_HUMAN,tr|A0A7P0T825|A0A7P0T825_HUMAN,tr|A0A2R8Y6H2|A0A2R8Y6H2_HUMAN,tr|A0A7P0TAM4|A0A7P0TAM4_HUMAN" 26 1186.6437 0.22 80044 10170 2 1186.637828 594.3291 Cytoplasmic dynein 1 heavy chain 1 OS=Homo sapiens OX=9606 GN=DYNC1H1 PE=1 SV=5 5.4 2036.9 - 817493 - - - -4.9804 - 1.724 0.362 - 412.5 1 2 0 -0.0059 10 0 0 0 9.73E+06 4.51E+07 - - - 3.2332 1 221125_WJC_METTL3_EV_vs_WT_F06.10175.10175.3 5.88E-06 18/56 R.AAAAQPIGHPDALER.A tr|A0A3B3IS91|A0A3B3IS91_HUMAN 1 1515.7794 1.79 80046 10175 3 1515.777067 506.2671 DNA polymerase subunit gamma-1 OS=Homo sapiens OX=9606 GN=POLG PE=1 SV=2 5.32 2037.5 - 3.08E+06 - - - -1.5325 - 2.88 0.492 - 411.4 1 2 0 -0.0023 15 0 0 0 5.30E+07 2.96E+07 - - - 6.7848 0.9856 221125_WJC_METTL3_EV_vs_WT_F06.10177.10177.2 0.0251 16-Aug K.QKEVEQLIK.K "sp|P25789|PSA4_HUMAN,tr|H0YN18|H0YN18_HUMAN" 2 1113.6394 1.55 80048 10177 2 1113.637149 557.827 Proteasome subunit alpha type-4 OS=Homo sapiens OX=9606 GN=PSMA4 PE=1 SV=1 6.14 2037.7 - 4.45E+06 - - - -1.998 - 1.555 0.341 - 197.6 1 2 1 -0.0022 9 0 0 0 1.04E+08 6.66E+07 - - - 2.8361 0.9994 221125_WJC_METTL3_EV_vs_WT_F06.10178.10178.3 7.69E-07 14/52 K.K[136.11]PPLLNNADSVQAK[136.11].V "sp|P09874|PARP1_HUMAN,tr|A0A7I2V3E1|A0A7I2V3E1_HUMAN" 2 1509.8486 1.11 80049 10178 3 1509.839634 504.2901 Poly [ADP-ribose] polymerase 1 OS=Homo sapiens OX=9606 GN=PARP1 PE=1 SV=4 8.59 2037.7 - 3.73E+06 - - - -5.933 - 2.981 0.519 - 315.2 1 2 0 -0.009 14 0 0 0 4.30E+08 3.88E+08 - - - 7.2266 0.9996 221125_WJC_METTL3_EV_vs_WT_F06.10179.10179.3 0.00122 13/40 -.MKPILLQGHER.S "sp|Q13347|EIF3I_HUMAN,tr|A0A7I2V613|A0A7I2V613_HUMAN,tr|A0A7I2V3N2|A0A7I2V3N2_HUMAN,tr|A0A7I2YQU2|A0A7I2YQU2_HUMAN,tr|A0A7I2YQX4|A0A7I2YQX4_HUMAN,tr|A0A7I2YQI6|A0A7I2YQI6_HUMAN,tr|A0A7I2YQF8|A0A7I2YQF8_HUMAN,tr|Q5TFK1|Q5TFK1_HUMAN,tr|A0A7I2V607|A0A7I2V607_HUMAN,tr|A0A7I2V640|A0A7I2V640_HUMAN,tr|A0A7P0MRT9|A0A7P0MRT9_HUMAN,tr|A0A7I2V3T4|A0A7I2V3T4_HUMAN,tr|A0A7I2V3K6|A0A7I2V3K6_HUMAN,tr|A0A7I2V4S8|A0A7I2V4S8_HUMAN,tr|A0A7I2V5V8|A0A7I2V5V8_HUMAN,tr|A0A7I2V391|A0A7I2V391_HUMAN,tr|A0A7I2V5E4|A0A7I2V5E4_HUMAN,tr|A0A7I2YQN1|A0A7I2YQN1_HUMAN,tr|A0A7I2V2M3|A0A7I2V2M3_HUMAN,tr|A0A7I2V4C2|A0A7I2V4C2_HUMAN,tr|A0A7I2YQP9|A0A7I2YQP9_HUMAN,tr|A0A7I2YQI2|A0A7I2YQI2_HUMAN,tr|A0A7I2V685|A0A7I2V685_HUMAN" 23 1320.7336 1.5 80050 10179 3 1320.729533 441.2518 Eukaryotic translation initiation factor 3 subunit I OS=Homo sapiens OX=9606 GN=EIF3I PE=1 SV=1 8.52 2037.8 - 2.46E+06 - - - -3.099 - 2.091 0.412 - 151.8 1 2 0 -0.0041 11 0 0 0 1.06E+08 7.04E+07 - - - 5.2278 0.9996 221125_WJC_METTL3_EV_vs_WT_F06.10183.10183.3 5.46E-06 Nov-32 R.ERLELC[160.03]DER.V sp|P07919|QCR6_HUMAN 1 1218.5663 1.25 80052 10183 3 1218.563262 407.196 "Cytochrome b-c1 complex subunit 6, mitochondrial OS=Homo sapiens OX=9606 GN=UQCRH PE=1 SV=2" 4.41 2038.2 - 5.18E+06 - - - -2.4816 - 2.031 0.522 - 303.6 1 2 1 -0.003 9 0 0 0 8.39E+07 6.69E+07 - - - 6.4943 0.9975 221125_WJC_METTL3_EV_vs_WT_F06.10184.10184.2 0.000464 18-Sep K.EFFNGK[136.11]EPSR[166.11].G "sp|P11021|BIP_HUMAN,tr|A0A7P0TB36|A0A7P0TB36_HUMAN,tr|A0A7P0TAI0|A0A7P0TAI0_HUMAN" 3 1227.6003 0.32 80053 10184 2 1227.601407 614.8074 Endoplasmic reticulum chaperone BiP OS=Homo sapiens OX=9606 GN=HSPA5 PE=1 SV=2 6.24 2038.3 - 2.17E+06 - - - 0.8969 - 1.804 0.483 - 311.1 1 2 1 0.0011 10 0 0 0 1.65E+07 5.20E+07 - - - 4.255 0.9999 221125_WJC_METTL3_EV_vs_WT_F06.10185.10185.3 4.72E-07 16/52 K.KPPLLNNADSVQAK.V "sp|P09874|PARP1_HUMAN,tr|A0A7I2V3E1|A0A7I2V3E1_HUMAN" 2 1493.8202 1.11 80054 10185 3 1493.815792 498.9473 Poly [ADP-ribose] polymerase 1 OS=Homo sapiens OX=9606 GN=PARP1 PE=1 SV=4 8.59 2038.4 - 4.41E+06 - - - -2.9455 - 3.034 0.536 - 569.8 1 2 0 -0.0044 14 0 0 0 4.30E+08 3.88E+08 - - - 7.4642 0.9999 221125_WJC_METTL3_EV_vs_WT_F06.10187.10187.3 9.37E-07 16/48 K.VPLVAEK[136.11]PLK[136.11]EPK[136.11].T "sp|P41250|GARS_HUMAN,tr|H7C443|H7C443_HUMAN,tr|A0A6Q8PGI6|A0A6Q8PGI6_HUMAN,tr|A0A6Q8PGA8|A0A6Q8PGA8_HUMAN,tr|A0A6Q8PGW4|A0A6Q8PGW4_HUMAN,tr|A0A6Q8PGZ8|A0A6Q8PGZ8_HUMAN,tr|A0A6Q8PHH9|A0A6Q8PHH9_HUMAN,tr|A0A6Q8PHI7|A0A6Q8PHI7_HUMAN,tr|A0A6Q8PFZ6|A0A6Q8PFZ6_HUMAN" 9 1470.9236 1.66 80056 10187 3 1470.924349 491.3151 Glycine--tRNA ligase OS=Homo sapiens OX=9606 GN=GARS1 PE=1 SV=3 8.47 2038.5 - 2.50E+06 - - - 0.5085 - 2.89 0.45 - 407.8 1 2 1 0.0007 13 0 0 0 1.17E+08 7.08E+07 - - - 6.4342 0.9937 221125_WJC_METTL3_EV_vs_WT_F06.10189.10189.2 0.000371 18-Nov K.LKGDDLQAIK.Q "sp|P0DMR1|HNRC4_HUMAN,sp|P07910|HNRPC_HUMAN,sp|O60812|HNRC1_HUMAN,sp|B2RXH8|HNRC2_HUMAN,sp|B7ZW38|HNRC3_HUMAN,tr|B4DY08|B4DY08_HUMAN,tr|G3V5V7|G3V5V7_HUMAN,tr|B2R5W2|B2R5W2_HUMAN,tr|G3V4C1|G3V4C1_HUMAN,tr|A0A0G2JPF8|A0A0G2JPF8_HUMAN,tr|A0A0G2JNQ3|A0A0G2JNQ3_HUMAN,tr|G3V576|G3V576_HUMAN,tr|G3V2D6|G3V2D6_HUMAN,tr|G3V4W0|G3V4W0_HUMAN,tr|G3V2Q1|G3V2Q1_HUMAN" 15 1099.6237 0.83 80058 10189 2 1099.621324 550.8191 Heterogeneous nuclear ribonucleoprotein C-like 4 OS=Homo sapiens OX=9606 GN=HNRNPCL4 PE=3 SV=1 5.96 2038.8 - 1.32E+06 - - - -2.1826 - 1.729 0.452 - 228.4 1 2 1 -0.0024 10 0 0 0 2.96E+07 3.58E+07 - - - 3.9071 0.9989 221125_WJC_METTL3_EV_vs_WT_F06.10190.10190.3 0.00071 Dec-36 K.EQMKVESLER.A "sp|O75410|TACC1_HUMAN,tr|E7EVI4|E7EVI4_HUMAN,tr|B4E3H6|B4E3H6_HUMAN,tr|H0YAY0|H0YAY0_HUMAN,tr|H0YBT8|H0YBT8_HUMAN,tr|E7ET87|E7ET87_HUMAN" 6 1247.618 0.58 80059 10190 3 1247.617549 416.8799 Transforming acidic coiled-coil-containing protein 1 OS=Homo sapiens OX=9606 GN=TACC1 PE=1 SV=2 4.79 2038.9 - 1.13E+06 - - - -0.3511 - 2.021 0.342 - 188.2 1 2 1 -0.0004 10 0 0 0 2.36E+07 4.05E+07 - - - 4.4076 1 221125_WJC_METTL3_EV_vs_WT_F06.10191.10191.2 1.65E-06 17/26 K.K[136.11]PPLLNNADSVQAK[136.11].V "sp|P09874|PARP1_HUMAN,tr|A0A7I2V3E1|A0A7I2V3E1_HUMAN" 2 1509.8486 1.15 80060 10191 2 1509.851733 755.9316 Poly [ADP-ribose] polymerase 1 OS=Homo sapiens OX=9606 GN=PARP1 PE=1 SV=4 8.59 2039 - 1.03E+06 - - - 2.0803 - 3.451 0.597 - 868.3 1 2 0 0.0031 14 0 0 0 6.04E+07 5.24E+07 - - - 6.5578 0.9944 221125_WJC_METTL3_EV_vs_WT_F06.10195.10195.2 0.627 18-Oct R.R[166.11]QAVDVSPLR[166.11].R "sp|P46782|RS5_HUMAN,tr|M0QZN2|M0QZN2_HUMAN,tr|M0R0F0|M0R0F0_HUMAN,tr|M0R0R2|M0R0R2_HUMAN" 4 1159.6576 0.97 80062 10195 2 1159.657596 580.8361 40S ribosomal protein S5 OS=Homo sapiens OX=9606 GN=RPS5 PE=1 SV=4 9.6 2039.5 - 5.11E+06 - - - -0.0423 - 1.749 0.056 - 136.2 1 2 0 -0.0001 10 0 0 0 1.08E+08 1.11E+08 - - - 1.0151 0.9984 221125_WJC_METTL3_EV_vs_WT_F06.10196.10196.2 0.00319 18-Oct K.VPQIEVETHK.V "sp|Q14204|DYHC1_HUMAN,tr|A0A7P0T8N2|A0A7P0T8N2_HUMAN,tr|A0A7P0T9C4|A0A7P0T9C4_HUMAN,tr|A0A7P0TBJ7|A0A7P0TBJ7_HUMAN,tr|A0A804HHY6|A0A804HHY6_HUMAN,tr|A0A7P0T9K2|A0A7P0T9K2_HUMAN,tr|A0A7P0TB64|A0A7P0TB64_HUMAN,tr|A0A2R8Y706|A0A2R8Y706_HUMAN,tr|A0A7P0T916|A0A7P0T916_HUMAN,tr|A0A7P0TB75|A0A7P0TB75_HUMAN,tr|A0A7P0T8W5|A0A7P0T8W5_HUMAN,tr|A0A7P0TAF3|A0A7P0TAF3_HUMAN,tr|A0A7P0T9F1|A0A7P0T9F1_HUMAN,tr|A0A7P0TAW9|A0A7P0TAW9_HUMAN,tr|A0A2R8YGC7|A0A2R8YGC7_HUMAN,tr|A0A7P0TA13|A0A7P0TA13_HUMAN,tr|A0A7P0TAV5|A0A7P0TAV5_HUMAN,tr|A0A7P0T7V5|A0A7P0T7V5_HUMAN,tr|A0A7P0T9R4|A0A7P0T9R4_HUMAN,tr|A0A2R8Y5T0|A0A2R8Y5T0_HUMAN,tr|A0A7P0T990|A0A7P0T990_HUMAN,tr|A0A7P0T942|A0A7P0T942_HUMAN,tr|A0A2R8YFZ7|A0A2R8YFZ7_HUMAN,tr|A0A7P0T825|A0A7P0T825_HUMAN,tr|A0A2R8Y6H2|A0A2R8Y6H2_HUMAN,tr|A0A7P0TAM4|A0A7P0TAM4_HUMAN" 26 1178.6295 0.2 80063 10196 2 1178.626432 590.322 Cytoplasmic dynein 1 heavy chain 1 OS=Homo sapiens OX=9606 GN=DYNC1H1 PE=1 SV=5 5.4 2039.7 - 658388 - - - -2.6353 - 1.817 0.32 - 420.3 1 2 0 -0.0031 10 0 0 0 9.73E+06 4.82E+07 - - - 3.0705 0.9866 221125_WJC_METTL3_EV_vs_WT_F06.10197.10197.2 0.000846 16/18 S.RSLYNLGGSK.R "sp|P13647|K2C5_HUMAN,tr|F8VV57|F8VV57_HUMAN" 2 1093.588 623.35 80064 10197 2 1093.588264 547.8013 "Keratin, type II cytoskeletal 5 OS=Homo sapiens OX=9606 GN=KRT5 PE=1 SV=3" 9.99 2039.8 - 2.78E+06 - - - 0.235 - 2.755 0.282 - 873.4 1 1 0 0.0003 10 0 0 0 4.27E+07 6.86E+04 - - - 3.9525 0.9986 221125_WJC_METTL3_EV_vs_WT_F06.10198.10198.2 2.23E-05 15/20 K.AK[136.11]EELSAALEK[136.11].A "sp|P82094|TMF1_HUMAN,tr|F8WF45|F8WF45_HUMAN" 2 1203.6682 1.75 80065 10198 2 1203.668884 602.8414 TATA element modulatory factor OS=Homo sapiens OX=9606 GN=TMF1 PE=1 SV=2 4.79 2039.9 - 1.52E+06 - - - 0.5948 - 2.851 0.422 - 468.2 1 2 1 0.0007 11 0 0 0 7.86E+07 4.48E+07 - - - 4.9919 1 221125_WJC_METTL3_EV_vs_WT_F06.10200.10200.2 1.47E-05 16/34 K.GEPAAAAAPEAGASPVEK[136.11].E sp|P29966|MARCS_HUMAN 1 1629.809 0.94 80067 10200 2 1629.809546 815.9118 Myristoylated alanine-rich C-kinase substrate OS=Homo sapiens OX=9606 GN=MARCKS PE=1 SV=4 4.25 2040.1 - 840389 - - - 0.3565 - 3.161 0.565 - 300.1 1 2 0 0.0006 18 0 0 0 2.44E+07 2.59E+07 - - - 6.0434 1 221125_WJC_METTL3_EV_vs_WT_F06.10201.10201.2 4.27E-10 20/26 K.KPPLLNNADSVQAK.V "sp|P09874|PARP1_HUMAN,tr|A0A7I2V3E1|A0A7I2V3E1_HUMAN" 2 1493.8202 1.15 80068 10201 2 1493.822965 747.9174 Poly [ADP-ribose] polymerase 1 OS=Homo sapiens OX=9606 GN=PARP1 PE=1 SV=4 8.59 2040.3 - 826608 - - - 1.8563 - 3.619 0.552 - 1139.4 1 2 0 0.0028 14 0 0 0 6.04E+07 5.24E+07 - - - 6.3448 1 221125_WJC_METTL3_EV_vs_WT_F06.10204.10204.2 0.00124 15/26 R.YGDGGSTFQSTTGH.C "sp|P31943|HNRH1_HUMAN,tr|H0YBD7|H0YBD7_HUMAN,tr|H0YB39|H0YB39_HUMAN,tr|H0YBG7|H0YBG7_HUMAN,tr|E9PCY7|E9PCY7_HUMAN,tr|D6RIT2|D6RIT2_HUMAN,tr|G8JLB6|G8JLB6_HUMAN" 7 1413.5797 - 80069 10204 2 1413.579009 707.7971 Heterogeneous nuclear ribonucleoprotein H OS=Homo sapiens OX=9606 GN=HNRNPH1 PE=1 SV=4 5.08 2040.7 - 2.53E+06 - - - -0.4796 - 3.001 0.659 - 472.9 1 1 0 -0.0007 14 0 0 0 - - - - - 6.6659 0.9998 221125_WJC_METTL3_EV_vs_WT_F06.10205.10205.2 9.64E-06 14/22 R.TLVAVKPDGVQR.R "sp|O00746|NDKM_HUMAN,tr|Q4TT34|Q4TT34_HUMAN,tr|A0A087WVT9|A0A087WVT9_HUMAN,tr|H0Y6J0|H0Y6J0_HUMAN,tr|F2Z2X0|F2Z2X0_HUMAN" 5 1281.7405 2.14 80070 10205 2 1281.738148 641.8775 "Nucleoside diphosphate kinase, mitochondrial OS=Homo sapiens OX=9606 GN=NME4 PE=1 SV=1" 8.41 2040.8 - 1.87E+06 - - - -1.8233 - 2.717 0.435 - 833.7 1 2 0 -0.0023 12 0 0 0 6.19E+07 2.90E+07 - - - 4.8831 0.9999 221125_WJC_METTL3_EV_vs_WT_F06.10207.10207.3 1.86E-05 18/48 K.APLKPYPVSPSDK.V "sp|P41252|SYIC_HUMAN,tr|A0A804HL54|A0A804HL54_HUMAN,tr|A0A804HJN6|A0A804HJN6_HUMAN,tr|A0A804HHW9|A0A804HHW9_HUMAN,tr|A0A0A0MSX9|A0A0A0MSX9_HUMAN,tr|J3KR24|J3KR24_HUMAN,tr|A0A804HJ36|A0A804HJ36_HUMAN" 7 1397.7555 0.71 80072 10207 3 1397.751914 466.9258 "Isoleucine--tRNA ligase, cytoplasmic OS=Homo sapiens OX=9606 GN=IARS1 PE=1 SV=2" 8.54 2041 - 1.45E+06 - - - -2.5419 - 3.218 0.445 - 496.2 1 2 0 -0.0036 13 0 0 0 4.82E+07 6.79E+07 - - - 6.6692 0.9998 221125_WJC_METTL3_EV_vs_WT_F06.10208.10208.2 4.09E-05 22-Dec R.LQDVSGQLSSSK[136.11].K sp|Q15059|BRD3_HUMAN 1 1255.6499 0.48 80073 10208 2 1255.651198 628.8322 Bromodomain-containing protein 3 OS=Homo sapiens OX=9606 GN=BRD3 PE=1 SV=1 5.84 2041.1 - 822215 - - - 0.9979 - 2.205 0.454 - 684.1 1 2 0 0.0013 12 0 0 0 6.21E+06 1.28E+07 - - - 4.4744 0.9993 221125_WJC_METTL3_EV_vs_WT_F06.10209.10209.2 8.27E-07 13/26 R.LGDTQQSIPGNEER.F "sp|P19474|RO52_HUMAN,tr|H0YDP8|H0YDP8_HUMAN" 2 1542.7274 1.75 80074 10209 2 1542.72155 772.371 E3 ubiquitin-protein ligase TRIM21 OS=Homo sapiens OX=9606 GN=TRIM21 PE=1 SV=1 4.14 2041.2 - 737940 - - - -3.8011 - 2.812 0.526 - 380.1 1 2 0 -0.0059 14 0 0 0 2.38E+07 1.36E+07 - - - 5.5187 0.9952 221125_WJC_METTL3_EV_vs_WT_F06.10213.10213.2 0.0847 16-Oct R.ER[166.11]LELC[160.03]DER[166.11].V sp|P07919|QCR6_HUMAN 1 1238.5828 1.02 80076 10213 2 1238.581024 620.2987 "Cytochrome b-c1 complex subunit 6, mitochondrial OS=Homo sapiens OX=9606 GN=UQCRH PE=1 SV=2" 4.41 2041.8 - 568762 - - - -1.4549 - 1.919 0.367 - 346.9 1 2 1 -0.0018 9 0 0 0 2.16E+07 2.12E+07 - - - 3.6368 1 221125_WJC_METTL3_EV_vs_WT_F06.10214.10214.3 2.32E-06 15/44 R.TLVAVKPDGVQR.R "sp|O00746|NDKM_HUMAN,tr|Q4TT34|Q4TT34_HUMAN,tr|A0A087WVT9|A0A087WVT9_HUMAN,tr|H0Y6J0|H0Y6J0_HUMAN,tr|F2Z2X0|F2Z2X0_HUMAN" 5 1281.7405 1.84 80077 10214 3 1281.739092 428.2541 "Nucleoside diphosphate kinase, mitochondrial OS=Homo sapiens OX=9606 GN=NME4 PE=1 SV=1" 8.41 2041.8 - 2.05E+07 - - - -1.0868 - 2.817 0.563 - 259.1 1 2 0 -0.0014 12 0 0 0 4.76E+08 2.58E+08 - - - 7.6872 0.9998 221125_WJC_METTL3_EV_vs_WT_F06.10215.10215.3 8.30E-06 14/48 K.VPLVAEKPLKEPK.T "sp|P41250|GARS_HUMAN,tr|H7C443|H7C443_HUMAN,tr|A0A6Q8PGI6|A0A6Q8PGI6_HUMAN,tr|A0A6Q8PGA8|A0A6Q8PGA8_HUMAN,tr|A0A6Q8PGW4|A0A6Q8PGW4_HUMAN,tr|A0A6Q8PGZ8|A0A6Q8PGZ8_HUMAN,tr|A0A6Q8PHH9|A0A6Q8PHH9_HUMAN,tr|A0A6Q8PHI7|A0A6Q8PHI7_HUMAN,tr|A0A6Q8PFZ6|A0A6Q8PFZ6_HUMAN" 9 1446.881 1.63 80078 10215 3 1446.881326 483.3009 Glycine--tRNA ligase OS=Homo sapiens OX=9606 GN=GARS1 PE=1 SV=3 8.47 2041.9 - 5.10E+06 - - - 0.2246 - 2.318 0.49 - 286.9 1 2 1 0.0003 13 0 0 0 1.16E+08 7.08E+07 - - - 6.2823 0.9999 221125_WJC_METTL3_EV_vs_WT_F06.10217.10217.3 1.08E-07 19/56 R.AAAAQPIGHPDALER[166.11].A tr|A0A3B3IS91|A0A3B3IS91_HUMAN 1 1525.7877 1.79 80080 10217 3 1525.781874 509.6032 DNA polymerase subunit gamma-1 OS=Homo sapiens OX=9606 GN=POLG PE=1 SV=2 5.32 2042 - 1.07E+06 - - - -3.7921 - 3.561 0.524 - 602.4 1 2 0 -0.0058 15 0 0 0 5.30E+07 2.96E+07 - - - 7.6945 1 221125_WJC_METTL3_EV_vs_WT_F06.10225.10225.3 0.000123 13/44 R.TLVAVK[136.11]PDGVQR[166.11].R "sp|O00746|NDKM_HUMAN,tr|Q4TT34|Q4TT34_HUMAN,tr|A0A087WVT9|A0A087WVT9_HUMAN,tr|H0Y6J0|H0Y6J0_HUMAN,tr|F2Z2X0|F2Z2X0_HUMAN" 5 1299.763 1.84 80086 10225 3 1299.762674 434.2616 "Nucleoside diphosphate kinase, mitochondrial OS=Homo sapiens OX=9606 GN=NME4 PE=1 SV=1" 8.41 2043 - 1.57E+07 - - - -0.2162 - 2.61 0.485 - 168.1 1 2 0 -0.0003 12 0 0 0 4.75E+08 2.58E+08 - - - 6.6064 0.9991 221125_WJC_METTL3_EV_vs_WT_F06.10227.10227.3 0.00192 Dec-48 K.APLK[136.11]PYPVSPSDK[136.11].V "sp|P41252|SYIC_HUMAN,tr|A0A804HL54|A0A804HL54_HUMAN,tr|A0A804HJN6|A0A804HJN6_HUMAN,tr|A0A804HHW9|A0A804HHW9_HUMAN,tr|A0A0A0MSX9|A0A0A0MSX9_HUMAN,tr|J3KR24|J3KR24_HUMAN,tr|A0A804HJ36|A0A804HJ36_HUMAN" 7 1413.7839 0.68 80088 10227 3 1413.787032 472.2686 "Isoleucine--tRNA ligase, cytoplasmic OS=Homo sapiens OX=9606 GN=IARS1 PE=1 SV=2" 8.54 2043.1 - 1.81E+06 - - - 2.2387 - 2.005 0.321 - 86.3 1 2 0 0.0032 13 0 0 0 4.72E+07 6.91E+07 - - - 4.004 0.9998 221125_WJC_METTL3_EV_vs_WT_F06.10228.10228.2 0.000991 13/22 R.TLVAVK[136.11]PDGVQR[166.11].R "sp|O00746|NDKM_HUMAN,tr|Q4TT34|Q4TT34_HUMAN,tr|A0A087WVT9|A0A087WVT9_HUMAN,tr|H0Y6J0|H0Y6J0_HUMAN,tr|F2Z2X0|F2Z2X0_HUMAN" 5 1299.763 2.14 80089 10228 2 1299.762912 650.8888 "Nucleoside diphosphate kinase, mitochondrial OS=Homo sapiens OX=9606 GN=NME4 PE=1 SV=1" 8.41 2043.2 - 1.54E+06 - - - -0.0331 - 2.454 0.408 - 582.5 1 2 0 0 12 0 0 0 6.19E+07 2.90E+07 - - - 4.4165 0.9306 221125_WJC_METTL3_EV_vs_WT_F06.10235.10235.2 0.0142 18-Aug L.VAVK[136.11]PDGVQR[166.11].R "sp|O00746|NDKM_HUMAN,tr|Q4TT34|Q4TT34_HUMAN,tr|A0A087WVT9|A0A087WVT9_HUMAN,tr|H0Y6J0|H0Y6J0_HUMAN,tr|F2Z2X0|F2Z2X0_HUMAN" 5 1085.6312 2.27 80094 10235 2 1085.630503 543.8229 "Nucleoside diphosphate kinase, mitochondrial OS=Homo sapiens OX=9606 GN=NME4 PE=1 SV=1" 8.72 2044 - 1.46E+06 - - - -0.654 - 1.47 0.287 - 168.5 1 1 0 -0.0007 10 0 0 0 4.47E+07 1.97E+07 - - - 2.2359 0.9961 221125_WJC_METTL3_EV_vs_WT_F06.10238.10238.2 0.0014 16-Oct K.SKIEDAFSK.E "sp|Q5VT06|CE350_HUMAN,tr|H0Y7F7|H0Y7F7_HUMAN" 2 1023.5237 0.56 80097 10238 2 1023.522869 512.7691 Centrosome-associated protein 350 OS=Homo sapiens OX=9606 GN=CEP350 PE=1 SV=1 5.79 2044.3 - 569791 - - - -0.7885 - 1.922 0.351 - 292.9 1 2 1 -0.0008 9 0 0 0 6.84E+06 1.22E+07 - - - 3.5235 0.9998 221125_WJC_METTL3_EV_vs_WT_F06.10239.10239.2 2.21E-05 16-Nov K.SNYNLPMHK.M "sp|P36578|RL4_HUMAN,tr|H3BM89|H3BM89_HUMAN" 2 1102.523 0.68 80098 10239 2 1102.521549 552.2688 60S ribosomal protein L4 OS=Homo sapiens OX=9606 GN=RPL4 PE=1 SV=5 8.33 2044.4 - 356903 - - - -1.2834 - 2.146 0.491 - 604.6 1 2 0 -0.0014 9 0 0 0 9.35E+06 1.37E+07 - - - 4.8762 0.9997 221125_WJC_METTL3_EV_vs_WT_F06.10240.10240.2 0.00269 22-Sep K.VGGTSDVEVNEK.K "sp|P10809|CH60_HUMAN,tr|A0A7I2V2X6|A0A7I2V2X6_HUMAN,tr|A0A7I2YQK6|A0A7I2YQK6_HUMAN,tr|A0A7I2V599|A0A7I2V599_HUMAN" 4 1232.5885 1.01 80099 10240 2 1232.590316 617.3015 "60 kDa heat shock protein, mitochondrial OS=Homo sapiens OX=9606 GN=HSPD1 PE=1 SV=2" 4.14 2044.6 - 284460 - - - 1.505 - 1.873 0.46 - 149.6 1 2 0 0.0019 12 0 0 0 3.19E+06 3.17E+06 - - - 4.0891 0.9994 221125_WJC_METTL3_EV_vs_WT_F06.10241.10241.2 0.000946 22-Oct R.LQDVSGQLSSSK.K sp|Q15059|BRD3_HUMAN 1 1247.6357 0.48 80100 10241 2 1247.637444 624.8251 Bromodomain-containing protein 3 OS=Homo sapiens OX=9606 GN=BRD3 PE=1 SV=1 5.84 2044.7 - 624819 - - - 1.3618 - 2.038 0.337 - 385.6 1 2 0 0.0017 12 0 0 0 6.21E+06 1.28E+07 - - - 3.4029 0.9739 221125_WJC_METTL3_EV_vs_WT_F06.10245.10245.2 0.00692 18-Nov L.VAVKPDGVQR.R "sp|O00746|NDKM_HUMAN,tr|Q4TT34|Q4TT34_HUMAN,tr|A0A087WVT9|A0A087WVT9_HUMAN,tr|H0Y6J0|H0Y6J0_HUMAN,tr|F2Z2X0|F2Z2X0_HUMAN" 5 1067.6087 2.25 80102 10245 2 1067.608914 534.8116 "Nucleoside diphosphate kinase, mitochondrial OS=Homo sapiens OX=9606 GN=NME4 PE=1 SV=1" 8.72 2045.2 - 3.15E+06 - - - 0.1602 - 1.688 0.359 - 316.8 1 1 0 0.0002 10 0 0 0 4.43E+07 1.97E+07 - - - 3.1539 1 221125_WJC_METTL3_EV_vs_WT_F06.10248.10248.2 7.85E-05 15/26 R.LGDTQQSIPGNEER[166.11].F "sp|P19474|RO52_HUMAN,tr|H0YDP8|H0YDP8_HUMAN" 2 1552.7357 1.75 80105 10248 2 1552.735607 777.3751 E3 ubiquitin-protein ligase TRIM21 OS=Homo sapiens OX=9606 GN=TRIM21 PE=1 SV=1 4.14 2045.4 - 1.10E+06 - - - -0.0496 - 3.039 0.596 - 498.3 1 2 0 -0.0001 14 0 0 0 2.38E+07 1.36E+07 - - - 6.2324 1 221125_WJC_METTL3_EV_vs_WT_F06.10250.10250.2 4.34E-07 13/22 R.TGYSMVQENGQR[166.11].K "sp|A0AV96|RBM47_HUMAN,tr|D6RBP6|D6RBP6_HUMAN,tr|D6RFL5|D6RFL5_HUMAN,tr|D6RA49|D6RA49_HUMAN,tr|D6RCT1|D6RCT1_HUMAN,tr|D6RBS9|D6RBS9_HUMAN,tr|B7Z8Z7|B7Z8Z7_HUMAN,tr|D6R9M7|D6R9M7_HUMAN,tr|D6REZ6|D6REZ6_HUMAN,tr|D6R9D6|D6R9D6_HUMAN" 10 1378.6175 1.37 80107 10250 2 1378.618044 690.316 RNA-binding protein 47 OS=Homo sapiens OX=9606 GN=RBM47 PE=1 SV=2 5.66 2045.7 - 424279 - - - 0.4069 - 2.677 0.652 - 519.4 1 2 0 0.0006 12 0 0 0 3.54E+07 2.58E+07 - - - 6.4474 0.9999 221125_WJC_METTL3_EV_vs_WT_F06.10251.10251.2 1.04E-06 24-Nov R.SGYGPSDGPSYGR[166.11].Y sp|O95429|BAG4_HUMAN 1 1308.561 0.64 80108 10251 2 1308.559939 655.2878 BAG family molecular chaperone regulator 4 OS=Homo sapiens OX=9606 GN=BAG4 PE=1 SV=1 5.55 2045.8 - 375684 - - - -0.8215 - 1.788 0.599 - 219.6 1 2 0 -0.0011 13 0 0 0 5.76E+06 8.98E+06 - - - 4.9563 0.9993 221125_WJC_METTL3_EV_vs_WT_F06.10252.10252.2 0.000808 24-Oct K.GADVNAPPVPSSR[166.11].D "sp|O75179|ANR17_HUMAN,sp|Q8IWZ3|ANKH1_HUMAN,tr|E9PDP5|E9PDP5_HUMAN,tr|H0YM23|H0YM23_HUMAN,tr|H3BLS9|H3BLS9_HUMAN,tr|H0YLQ3|H0YLQ3_HUMAN,tr|H7C2F5|H7C2F5_HUMAN" 7 1275.6447 1.8 80109 10252 2 1275.647726 638.8296 Ankyrin repeat domain-containing protein 17 OS=Homo sapiens OX=9606 GN=ANKRD17 PE=1 SV=3 5.84 2045.9 - 356164 - - - 2.3847 - 1.943 0.419 - 261.5 1 2 0 0.003 13 0 0 0 4.71E+08 2.61E+08 - - - 3.8396 0.9996 221125_WJC_METTL3_EV_vs_WT_F06.10254.10254.2 0.000152 24-Nov K.ESVSSVAQENAVK[136.11].D "sp|Q6N021|TET2_HUMAN,tr|E7EQS8|E7EQS8_HUMAN,tr|E7EPB1|E7EPB1_HUMAN" 3 1354.682 5.42 80111 10254 2 1354.683697 678.3483 Methylcytosine dioxygenase TET2 OS=Homo sapiens OX=9606 GN=TET2 PE=1 SV=3 4.53 2046.2 - 228282 - - - 1.2719 - 1.858 0.406 - 181.9 1 2 0 0.0017 13 0 0 0 6.57E+06 1.21E+06 - - - 3.6291 0.9998 221125_WJC_METTL3_EV_vs_WT_F06.10256.10256.2 0.0055 18-Oct R.RQAVDVSPLR.R "sp|P46782|RS5_HUMAN,tr|M0QZN2|M0QZN2_HUMAN,tr|M0R0F0|M0R0F0_HUMAN,tr|M0R0R2|M0R0R2_HUMAN" 4 1139.6411 0.97 80112 10256 2 1139.64124 570.8278 40S ribosomal protein S5 OS=Homo sapiens OX=9606 GN=RPS5 PE=1 SV=4 9.6 2046.5 - 4.75E+06 - - - 0.1185 - 2.414 0.378 - 153.7 1 2 0 0.0001 10 0 0 0 1.08E+08 1.11E+08 - - - 4.2928 1 221125_WJC_METTL3_EV_vs_WT_F06.10258.10258.3 8.88E-06 17/44 K.HLVGGLHTVYTK.L "sp|Q9UI36|DACH1_HUMAN,sp|Q96NX9|DACH2_HUMAN,tr|D6RFG7|D6RFG7_HUMAN,tr|D6REJ4|D6REJ4_HUMAN" 4 1323.7299 2.43 80113 10258 3 1323.730167 442.2506 Dachshund homolog 1 OS=Homo sapiens OX=9606 GN=DACH1 PE=1 SV=4 8.61 2046.7 - 5.46E+06 - - - 0.1866 - 2.988 0.486 - 290.4 1 2 0 0.0002 12 0 0 0 1.62E+08 6.70E+07 - - - 6.9924 1 221125_WJC_METTL3_EV_vs_WT_F06.10259.10259.3 3.07E-07 16/44 K.HLVGGLHTVYTK[136.11].L "sp|Q9UI36|DACH1_HUMAN,sp|Q96NX9|DACH2_HUMAN,tr|D6RFG7|D6RFG7_HUMAN,tr|D6REJ4|D6REJ4_HUMAN" 4 1331.7441 2.31 80114 10259 3 1331.744526 444.922 Dachshund homolog 1 OS=Homo sapiens OX=9606 GN=DACH1 PE=1 SV=4 8.61 2046.7 - 2.70E+06 - - - 0.3049 - 2.802 0.528 - 269.3 1 2 0 0.0004 12 0 0 0 1.55E+08 6.70E+07 - - - 7.2825 1 221125_WJC_METTL3_EV_vs_WT_F06.10260.10260.2 0.000741 26-Dec R.GFSSGSAVVSGGSR.R sp|P35908|K22E_HUMAN 1 1253.6 20547.57 80115 10260 2 1253.600984 627.8073 "Keratin, type II cytoskeletal 2 epidermal OS=Homo sapiens OX=9606 GN=KRT2 PE=1 SV=2" 9.75 2046.8 - 2.52E+06 - - - 0.7618 - 2.662 0.596 - 452.9 1 2 0 0.001 14 0 0 0 4.21E+09 2.05E+05 - - - 5.8997 0.9999 221125_WJC_METTL3_EV_vs_WT_F06.10261.10261.2 6.08E-06 16-Sep K.VTMQNLNDR.L "sp|P13645|K1C10_HUMAN,sp|Q7Z3Z0|K1C25_HUMAN,sp|Q7Z3Y9|K1C26_HUMAN,sp|P02533|K1C14_HUMAN,sp|Q7Z3Y8|K1C27_HUMAN,sp|P08779|K1C16_HUMAN,sp|Q7Z3Y7|K1C28_HUMAN,tr|A0A1B0GVI3|A0A1B0GVI3_HUMAN" 8 1089.5237 999 80116 10261 2 1089.523939 545.7691 "Keratin, type I cytoskeletal 10 OS=Homo sapiens OX=9606 GN=KRT10 PE=1 SV=6" 5.81 2046.9 - 2.49E+06 - - - 0.2267 - 2.044 0.517 - 514.2 1 2 0 0.0002 9 0 0 0 1.27E+08 0.00E+00 - - - 4.9278 0.9996 221125_WJC_METTL3_EV_vs_WT_F06.10262.10262.2 0.000204 20-Nov K.TIIQNPTDQQK[136.11].K "sp|Q9UQ80|PA2G4_HUMAN,tr|F8VR77|F8VR77_HUMAN" 2 1292.6816 0.12 80117 10262 2 1292.683595 647.3481 Proliferation-associated protein 2G4 OS=Homo sapiens OX=9606 GN=PA2G4 PE=1 SV=3 5.5 2046.9 - 2.33E+06 - - - 1.5588 - 1.833 0.451 - 328.4 1 2 0 0.002 11 0 0 0 5.37E+07 4.39E+08 - - - 4.0107 0.9889 221125_WJC_METTL3_EV_vs_WT_F06.10264.10264.3 0.161 Aug-44 R.VSMSPVLHTQNK.E sp|Q8TEM1|PO210_HUMAN 1 1339.6918 1.94 80119 10264 3 1339.692352 447.5712 Nuclear pore membrane glycoprotein 210 OS=Homo sapiens OX=9606 GN=NUP210 PE=1 SV=3 8.73 2047.1 - 2.51E+06 - - - 0.3971 - 1.312 0.22 - 49 1 2 0 0.0005 12 0 0 0 4.20E+07 2.17E+07 - - - 1.7453 0.9992 221125_WJC_METTL3_EV_vs_WT_F06.10267.10267.3 0.311 Nov-44 R.VSMSPVLHTQNK[136.11].E sp|Q8TEM1|PO210_HUMAN 1 1347.706 1.86 80122 10267 3 1347.708203 450.2426 Nuclear pore membrane glycoprotein 210 OS=Homo sapiens OX=9606 GN=NUP210 PE=1 SV=3 8.73 2047.3 - 967682 - - - 1.6198 - 2.134 0.281 - 105.9 1 2 0 0.0022 12 0 0 0 4.20E+07 2.26E+07 - - - 3.7733 1 221125_WJC_METTL3_EV_vs_WT_F06.10268.10268.3 1.18E-05 Dec-48 R.SVLPEGPVGHSGK.L "sp|O75970|MPDZ_HUMAN,tr|F5H1U9|F5H1U9_HUMAN" 2 1262.6619 1.36 80123 10268 3 1262.662666 421.8946 Multiple PDZ domain protein OS=Homo sapiens OX=9606 GN=MPDZ PE=1 SV=2 6.47 2047.4 - 743680 - - - 0.6067 - 2.453 0.508 - 173.3 1 2 0 0.0008 13 0 0 0 3.42E+07 2.51E+07 - - - 6.6364 1 221125_WJC_METTL3_EV_vs_WT_F06.10269.10269.2 1.00E-09 22-Dec K.NNASTDYDLSDK.S "sp|P39023|RL3_HUMAN,tr|G5E9G0|G5E9G0_HUMAN,tr|B5MCW2|B5MCW2_HUMAN" 3 1341.5685 0.8 80124 10269 2 1341.570867 671.7915 60S ribosomal protein L3 OS=Homo sapiens OX=9606 GN=RPL3 PE=1 SV=2 3.93 2047.5 - 613989 - - - 1.7986 - 2.223 0.664 - 336.8 1 2 0 0.0024 12 0 0 0 7.40E+06 9.23E+06 - - - 6.0465 0.9999 221125_WJC_METTL3_EV_vs_WT_F06.10270.10270.2 2.95E-05 24-Dec K.LNLGTDSDSSPQK.S "sp|Q16512|PKN1_HUMAN,tr|K7EN76|K7EN76_HUMAN" 2 1360.647 2.65 80125 10270 2 1360.646929 681.3308 Serine\threonine-protein kinase N1 OS=Homo sapiens OX=9606 GN=PKN1 PE=1 SV=2 4.21 2047.7 - 537926 - - - -0.0801 - 2.161 0.532 - 414.5 1 2 0 -0.0001 13 0 0 0 2.38E+07 9.01E+06 - - - 4.948 0.9993 221125_WJC_METTL3_EV_vs_WT_F06.10275.10275.3 0.0126 Oct-32 K.YK[136.11]PLDLR[166.11]PK[136.11].K sp|P42766|RL35_HUMAN 1 1154.7022 0.001 80128 10275 3 1154.702673 385.908 60S ribosomal protein L35 OS=Homo sapiens OX=9606 GN=RPL35 PE=1 SV=2 9.7 2048.3 - 1.26E+07 - - - 0.4105 - 2.029 0.258 - 111.4 1 2 0 0.0005 9 0 0 0 0.00E+00 1.92E+08 - - - 3.5487 0.9999 221125_WJC_METTL3_EV_vs_WT_F06.10276.10276.2 2.39E-08 18-Nov R.DQNTVETLQR.M "sp|Q01082|SPTB2_HUMAN,tr|A0A087WUZ3|A0A087WUZ3_HUMAN" 2 1202.5891 1.47 80129 10276 2 1202.590714 602.3018 "Spectrin beta chain, non-erythrocytic 1 OS=Homo sapiens OX=9606 GN=SPTBN1 PE=1 SV=2" 4.37 2048.3 - 3.09E+06 - - - 1.318 - 2.508 0.545 - 673.4 1 2 0 0.0016 10 0 0 0 4.90E+07 3.34E+07 - - - 5.6324 0.999 221125_WJC_METTL3_EV_vs_WT_F06.10277.10277.3 9.95E-05 Dec-44 R.LR[166.11]AEPDHMVLGK[136.11].R "sp|P41252|SYIC_HUMAN,tr|A0A804HL54|A0A804HL54_HUMAN,tr|A0A804HIV9|A0A804HIV9_HUMAN,tr|A0A804HJN6|A0A804HJN6_HUMAN,tr|A0A804HHW9|A0A804HHW9_HUMAN,tr|A0A0A0MSX9|A0A0A0MSX9_HUMAN,tr|J3KR24|J3KR24_HUMAN,tr|A0A804HJ36|A0A804HJ36_HUMAN" 8 1382.7459 0.8 80130 10277 3 1382.749031 461.9226 "Isoleucine--tRNA ligase, cytoplasmic OS=Homo sapiens OX=9606 GN=IARS1 PE=1 SV=2" 6.75 2048.4 - 2.42E+06 - - - 2.2463 - 2.341 0.387 - 187.4 1 2 1 0.0031 12 0 0 0 2.81E+07 3.53E+07 - - - 5.2115 0.9999 221125_WJC_METTL3_EV_vs_WT_F06.10278.10278.3 2.27E-06 16/44 R.LRAEPDHMVLGK.R "sp|P41252|SYIC_HUMAN,tr|A0A804HL54|A0A804HL54_HUMAN,tr|A0A804HIV9|A0A804HIV9_HUMAN,tr|A0A804HJN6|A0A804HJN6_HUMAN,tr|A0A804HHW9|A0A804HHW9_HUMAN,tr|A0A0A0MSX9|A0A0A0MSX9_HUMAN,tr|J3KR24|J3KR24_HUMAN,tr|A0A804HJ36|A0A804HJ36_HUMAN" 8 1364.7235 0.8 80131 10278 3 1364.72523 455.9151 "Isoleucine--tRNA ligase, cytoplasmic OS=Homo sapiens OX=9606 GN=IARS1 PE=1 SV=2" 6.75 2048.4 - 2.11E+06 - - - 1.3006 - 2.831 0.506 - 397.3 1 2 1 0.0018 12 0 0 0 2.83E+07 3.53E+07 - - - 7.0654 0.9999 221125_WJC_METTL3_EV_vs_WT_F06.10279.10279.2 0.000399 13/22 R.TGYSMVQENGQR.K "sp|A0AV96|RBM47_HUMAN,tr|D6RBP6|D6RBP6_HUMAN,tr|D6RFL5|D6RFL5_HUMAN,tr|D6RA49|D6RA49_HUMAN,tr|D6RCT1|D6RCT1_HUMAN,tr|D6RBS9|D6RBS9_HUMAN,tr|B7Z8Z7|B7Z8Z7_HUMAN,tr|D6R9M7|D6R9M7_HUMAN,tr|D6REZ6|D6REZ6_HUMAN,tr|D6R9D6|D6R9D6_HUMAN" 10 1368.6092 1.17 80132 10279 2 1368.609193 685.3119 RNA-binding protein 47 OS=Homo sapiens OX=9606 GN=RBM47 PE=1 SV=2 5.66 2048.6 - 1.36E+06 - - - -0.0146 - 2.44 0.586 - 530 1 2 0 0 12 0 0 0 3.01E+07 2.58E+07 - - - 5.7162 0.9999 221125_WJC_METTL3_EV_vs_WT_F06.10283.10283.2 1.24E-05 22-Oct K.NNASTDYDLSDK[136.11].S "sp|P39023|RL3_HUMAN,tr|G5E9G0|G5E9G0_HUMAN,tr|B5MCW2|B5MCW2_HUMAN" 3 1349.5827 0.8 80136 10283 2 1349.584371 675.7986 60S ribosomal protein L3 OS=Homo sapiens OX=9606 GN=RPL3 PE=1 SV=2 3.93 2049 - 614475 - - - 1.2722 - 2.055 0.602 - 224.6 1 2 0 0.0017 12 0 0 0 7.40E+06 9.23E+06 - - - 5.382 0.9056 221125_WJC_METTL3_EV_vs_WT_F06.10285.10285.2 0.0324 16-Aug K.YKPLDLRPK.K sp|P42766|RL35_HUMAN 1 1128.6655 0.58 80138 10285 2 1128.669607 565.34 60S ribosomal protein L35 OS=Homo sapiens OX=9606 GN=RPL35 PE=1 SV=2 9.7 2049.2 - 395655 - - - 3.6131 - 1.356 0.062 - 170.9 1 2 0 0.0041 9 0 0 0 8.28E+06 1.44E+07 - - - 0.3787 0.9999 221125_WJC_METTL3_EV_vs_WT_F06.10288.10288.2 1.38E-08 22-Nov R.SSSEDAESLAPR.S "sp|Q4G0J3|LARP7_HUMAN,tr|H0YA82|H0YA82_HUMAN" 2 1247.563 36.58 80141 10288 2 1247.563059 624.7888 La-related protein 7 OS=Homo sapiens OX=9606 GN=LARP7 PE=1 SV=1 4.14 2049.6 - 253608 - - - 0.0681 - 2.078 0.628 - 453.3 1 2 0 0.0001 12 0 0 0 3.49E+08 9.55E+06 - - - 5.6038 0.9994 221125_WJC_METTL3_EV_vs_WT_F06.10293.10293.3 9.11E-05 Dec-36 K.EFFNGKEPSR.G "sp|P11021|BIP_HUMAN,tr|A0A7P0TB36|A0A7P0TB36_HUMAN,tr|A0A7P0TAI0|A0A7P0TAI0_HUMAN" 3 1209.5778 0.58 80144 10293 3 1209.580884 404.1999 Endoplasmic reticulum chaperone BiP OS=Homo sapiens OX=9606 GN=HSPA5 PE=1 SV=2 6.24 2050.2 - 5.47E+06 - - - 2.5199 - 2.193 0.462 - 130.1 1 2 1 0.003 10 0 0 0 9.43E+07 1.61E+08 - - - 5.9833 0.9895 221125_WJC_METTL3_EV_vs_WT_F06.10296.10296.2 2.90E-07 20-Sep Q.NNAQGPLYEQR.S "sp|Q14157|UBP2L_HUMAN,tr|F8W726|F8W726_HUMAN" 2 1288.616 1.55 80147 10296 2 1288.618122 645.3153 Ubiquitin-associated protein 2-like OS=Homo sapiens OX=9606 GN=UBAP2L PE=1 SV=2 6 2050.5 - 1.16E+06 - - - 1.6366 - 1.994 0.599 - 283.3 1 1 0 0.0021 11 0 0 0 2.00E+07 1.29E+07 - - - 5.3316 0.9925 221125_WJC_METTL3_EV_vs_WT_F06.10297.10297.2 0.0523 16-Jun K.YK[136.11]PLDLR[166.11]PK[136.11].K sp|P42766|RL35_HUMAN 1 1154.7022 1.51 80148 10297 2 1154.702764 578.3584 60S ribosomal protein L35 OS=Homo sapiens OX=9606 GN=RPL35 PE=1 SV=2 9.7 2050.6 - 897834 - - - 0.4893 - 1.235 0.194 - 70.4 3 2 0 0.0006 9 0 0 0 2.59E+07 1.71E+07 - - - 0.8712 1 221125_WJC_METTL3_EV_vs_WT_F06.10300.10300.2 2.36E-09 15/24 K.NLDGISHAPNAVK.T "sp|Q92820|GGH_HUMAN,tr|A0A7I2YQQ3|A0A7I2YQQ3_HUMAN" 2 1334.6943 3.33 80151 10300 2 1334.694077 668.3544 Gamma-glutamyl hydrolase OS=Homo sapiens OX=9606 GN=GGH PE=1 SV=2 6.74 2051 - 498408 - - - -0.1394 - 2.768 0.559 - 638.3 1 2 0 -0.0002 13 0 0 0 7.73E+06 2.32E+06 - - - 5.7828 0.9755 221125_WJC_METTL3_EV_vs_WT_F06.10304.10304.3 2.24 Nov-52 R.GFSSGSAVVSGGSR.R sp|P35908|K22E_HUMAN 1 1253.6 49.62 80153 10304 3 1253.599855 418.874 "Keratin, type II cytoskeletal 2 epidermal OS=Homo sapiens OX=9606 GN=KRT2 PE=1 SV=2" 9.75 2051.5 - 1.86E+06 - - - -0.1388 - 1.991 0.081 - 144.7 1 2 0 -0.0002 14 0 0 0 8.06E+07 1.62E+06 - - - 1.2731 0.999 221125_WJC_METTL3_EV_vs_WT_F06.10309.10309.2 0.000308 24-Oct R.NSEPAGLETPEAK[136.11].V "sp|P07814|SYEP_HUMAN,tr|V9GYZ6|V9GYZ6_HUMAN" 2 1349.6554 0.93 80158 10309 2 1349.658516 675.835 Bifunctional glutamate\proline--tRNA ligase OS=Homo sapiens OX=9606 GN=EPRS1 PE=1 SV=5 4.25 2052 - 508496 - - - 2.2902 - 1.641 0.42 - 226.1 1 2 0 0.0031 13 0 0 0 1.87E+08 2.02E+08 - - - 3.4134 0.9998 221125_WJC_METTL3_EV_vs_WT_F06.10310.10310.2 7.60E-06 26-Oct K.LSELQETSEQAQSK.F sp|Q5T1M5|FKB15_HUMAN 1 1576.758 2.57 80159 10310 2 1576.76106 789.3863 FK506-binding protein 15 OS=Homo sapiens OX=9606 GN=FKBP15 PE=1 SV=2 4.25 2052.1 - 487342 - - - 1.9122 - 2.43 0.539 - 314.3 1 2 0 0.003 14 0 0 0 1.85E+07 7.19E+06 - - - 5.2492 0.9964 221125_WJC_METTL3_EV_vs_WT_F06.10311.10311.2 0.0824 22-Jun R.VSMSPVLHTQNK.E sp|Q8TEM1|PO210_HUMAN 1 1339.6918 21.37 80160 10311 2 1339.69232 670.8532 Nuclear pore membrane glycoprotein 210 OS=Homo sapiens OX=9606 GN=NUP210 PE=1 SV=3 8.73 2052.3 - 380352 - - - 0.3732 - 1.385 0.218 - 97.4 2 2 0 0.0005 12 0 0 0 6.44E+06 3.01E+05 - - - 1.3735 0.9998 221125_WJC_METTL3_EV_vs_WT_F06.10313.10313.2 0.00745 26-Nov K.LSELQETSEQAQSK[136.11].F sp|Q5T1M5|FKB15_HUMAN 1 1584.7722 2.57 80162 10313 2 1584.774806 793.3934 FK506-binding protein 15 OS=Homo sapiens OX=9606 GN=FKBP15 PE=1 SV=2 4.25 2052.5 - 140343 - - - 1.616 - 2.437 0.482 - 431.7 1 2 0 0.0026 14 0 0 0 1.85E+07 7.19E+06 - - - 4.8356 0.9995 221125_WJC_METTL3_EV_vs_WT_F06.10320.10320.2 0.00195 14-Aug K.DFSDITK[136.11]K[136.11].L sp|Q9NR30|DDX21_HUMAN 1 968.515 1.44 80167 10320 2 968.513811 485.2648 Nucleolar RNA helicase 2 OS=Homo sapiens OX=9606 GN=DDX21 PE=1 SV=5 5.96 2053.2 - 1.42E+06 - - - -1.1884 - 1.647 0.363 - 190.6 1 2 0 -0.0012 8 0 0 0 5.00E+07 3.46E+07 - - - 3.2266 0.9993 221125_WJC_METTL3_EV_vs_WT_F06.10321.10321.2 0.00319 22-Aug R.TQPMTAQAASYR[166.11].A sp|Q96PK6|RBM14_HUMAN 1 1333.6324 1.75 80168 10321 2 1333.629271 667.8235 RNA-binding protein 14 OS=Homo sapiens OX=9606 GN=RBM14 PE=1 SV=2 8.41 2053.3 - 895993 - - - -2.35 - 1.787 0.428 - 182.1 1 2 0 -0.0031 12 0 0 0 2.59E+07 1.48E+07 - - - 3.7287 0.9998 221125_WJC_METTL3_EV_vs_WT_F06.10328.10328.2 6.59E-07 22-Dec R.TQPMTAQAASYR.A sp|Q96PK6|RBM14_HUMAN 1 1323.6241 1.68 80173 10328 2 1323.622159 662.8193 RNA-binding protein 14 OS=Homo sapiens OX=9606 GN=RBM14 PE=1 SV=2 8.41 2054.2 - 1.24E+06 - - - -1.4929 - 1.971 0.593 - 516.1 1 2 0 -0.002 12 0 0 0 2.59E+07 1.55E+07 - - - 5.2056 0.9993 221125_WJC_METTL3_EV_vs_WT_F06.10333.10333.3 4.86E-05 14/44 R.VLIK[136.11]PEIQNNQK[136.11].N "sp|Q9HAU0|PKHA5_HUMAN,tr|A0JP02|A0JP02_HUMAN,tr|B4DJX4|B4DJX4_HUMAN" 3 1438.8479 1.01 80178 10333 3 1438.848543 480.6232 Pleckstrin homology domain-containing family A member 5 OS=Homo sapiens OX=9606 GN=PLEKHA5 PE=1 SV=1 8.56 2054.7 - 422507 - - - 0.4719 - 1.925 0.287 - 162.4 1 2 0 0.0007 12 0 0 0 9.07E+06 8.99E+06 - - - 3.5549 0.9707 221125_WJC_METTL3_EV_vs_WT_F06.10337.10337.2 0.0653 14-Jul L.KWLDSDAR.N "sp|P34913|HYES_HUMAN,tr|E5RFU2|E5RFU2_HUMAN,tr|E5RFH6|E5RFH6_HUMAN" 3 989.493 999 80180 10337 2 989.492764 495.7538 Bifunctional epoxide hydrolase 2 OS=Homo sapiens OX=9606 GN=EPHX2 PE=1 SV=2 5.96 2055.2 - 2.61E+06 - - - -0.283 - 1.463 0.383 - 288.2 1 1 0 -0.0003 8 0 0 0 5.15E+10 0.00E+00 - - - 3.0173 0.9999 221125_WJC_METTL3_EV_vs_WT_F06.10340.10340.3 2.57E-05 13/48 K.HVIADQEVMETNR.V sp|Q9H307|PININ_HUMAN 1 1540.7304 2.4 80183 10340 3 1540.725719 514.5841 Pinin OS=Homo sapiens OX=9606 GN=PNN PE=1 SV=5 4.65 2055.5 - 889438 - - - -3.0323 - 2.764 0.531 - 323.6 1 2 0 -0.0047 13 0 0 0 3.35E+07 1.40E+07 - - - 7.2153 0.9083 221125_WJC_METTL3_EV_vs_WT_F06.10343.10343.3 0.4 Jun-48 K.C[160.03]SEC[160.03]GESFSR[166.11]SSR.L "sp|O14978|ZN263_HUMAN,tr|I3L4C4|I3L4C4_HUMAN,tr|I3L538|I3L538_HUMAN,tr|B4DI05|B4DI05_HUMAN" 4 1557.6176 - 80186 10343 3 1557.616262 520.2131 Zinc finger protein 263 OS=Homo sapiens OX=9606 GN=ZNF263 PE=1 SV=2 6.13 2055.9 - 380501 - - - -0.8333 - 0.988 0.255 - 31.5 1 2 1 -0.0013 13 0 0 0 - - - - - 1.3499 0.9999 221125_WJC_METTL3_EV_vs_WT_F06.10346.10346.2 1.84E-06 24-Nov K.GADVNAPPVPSSR.D "sp|O75179|ANR17_HUMAN,sp|Q8IWZ3|ANKH1_HUMAN,tr|E9PDP5|E9PDP5_HUMAN,tr|H0YM23|H0YM23_HUMAN,tr|H3BLS9|H3BLS9_HUMAN,tr|H0YLQ3|H0YLQ3_HUMAN,tr|H7C2F5|H7C2F5_HUMAN" 7 1265.6364 1.75 80188 10346 2 1265.635426 633.8255 Ankyrin repeat domain-containing protein 17 OS=Homo sapiens OX=9606 GN=ANKRD17 PE=1 SV=3 5.84 2056.3 - 1.55E+07 - - - -0.7806 - 2.281 0.58 - 335.1 1 2 0 -0.001 13 0 0 0 4.54E+08 2.60E+08 - - - 5.441 0.9998 221125_WJC_METTL3_EV_vs_WT_F06.10348.10348.3 0.0016 Nov-36 K.EISTPTHWSK.L "sp|Q8IX12|CCAR1_HUMAN,tr|F5H2E6|F5H2E6_HUMAN,tr|F5H1H2|F5H1H2_HUMAN,tr|A0A0C4DGG8|A0A0C4DGG8_HUMAN" 4 1184.5826 35.18 80189 10348 3 1184.581536 395.8681 Cell division cycle and apoptosis regulator protein 1 OS=Homo sapiens OX=9606 GN=CCAR1 PE=1 SV=2 6.85 2056.5 - 1.34E+06 - - - -0.8881 - 1.965 0.369 - 153.5 1 2 0 -0.0011 10 0 0 0 2.56E+08 7.27E+06 - - - 4.6264 0.9912 221125_WJC_METTL3_EV_vs_WT_F06.10349.10349.3 0.00234 Sep-40 K.QDYKEGEMTLK.S "sp|P25789|PSA4_HUMAN,tr|H0YKS0|H0YKS0_HUMAN,tr|H0YKT8|H0YKT8_HUMAN,tr|H0YMI6|H0YMI6_HUMAN,tr|H0YMA1|H0YMA1_HUMAN,tr|H0YL69|H0YL69_HUMAN,tr|H0YN18|H0YN18_HUMAN,tr|H0YMZ1|H0YMZ1_HUMAN" 8 1340.6282 1.36 80190 10349 3 1340.626162 447.8833 Proteasome subunit alpha type-4 OS=Homo sapiens OX=9606 GN=PSMA4 PE=1 SV=1 4.68 2056.6 - 1.27E+06 - - - -1.5329 - 1.49 0.303 - 96.7 1 2 1 -0.0021 11 0 0 0 2.50E+07 1.83E+07 - - - 3.0504 0.9999 221125_WJC_METTL3_EV_vs_WT_F06.10351.10351.2 0.0105 20-Dec K.NQITTLQGQAK.N "sp|Q92540|SMG7_HUMAN,tr|E9PD50|E9PD50_HUMAN,tr|D6RAD0|D6RAD0_HUMAN,tr|E9PEK3|E9PEK3_HUMAN,tr|B1ALB4|B1ALB4_HUMAN" 5 1200.6463 2.05 80192 10351 2 1200.645554 601.3304 Protein SMG7 OS=Homo sapiens OX=9606 GN=SMG7 PE=1 SV=2 8.75 2056.8 - 1.37E+06 - - - -0.5797 - 2.324 0.492 - 607.2 1 2 0 -0.0007 11 0 0 0 1.53E+07 7.46E+06 - - - 4.956 0.9999 221125_WJC_METTL3_EV_vs_WT_F06.10352.10352.2 1.06E-06 24-Nov R.NSEPAGLETPEAK.V "sp|P07814|SYEP_HUMAN,tr|V9GYZ6|V9GYZ6_HUMAN" 2 1341.6412 0.58 80193 10352 2 1341.641817 671.8279 Bifunctional glutamate\proline--tRNA ligase OS=Homo sapiens OX=9606 GN=EPRS1 PE=1 SV=5 4.25 2056.9 - 862092 - - - 0.4413 - 2.328 0.575 - 476.8 1 2 0 0.0006 13 0 0 0 2.08E+07 3.62E+07 - - - 5.4565 0.9895 221125_WJC_METTL3_EV_vs_WT_F06.10354.10354.2 0.613 18-Jul K.EISTPTHWSK.L "sp|Q8IX12|CCAR1_HUMAN,tr|F5H2E6|F5H2E6_HUMAN,tr|F5H1H2|F5H1H2_HUMAN,tr|A0A0C4DGG8|A0A0C4DGG8_HUMAN" 4 1184.5826 16.37 80195 10354 2 1184.583999 593.2986 Cell division cycle and apoptosis regulator protein 1 OS=Homo sapiens OX=9606 GN=CCAR1 PE=1 SV=2 6.85 2057.1 - 551008 - - - 1.1911 - 1.187 0.179 - 139.7 1 2 0 0.0014 10 0 0 0 7.34E+07 4.48E+06 - - - 0.8412 0.9987 221125_WJC_METTL3_EV_vs_WT_F06.10355.10355.2 0.0276 20-Oct K.NQITTLQGQAK[136.11].N "sp|Q92540|SMG7_HUMAN,tr|E9PD50|E9PD50_HUMAN,tr|D6RAD0|D6RAD0_HUMAN,tr|E9PEK3|E9PEK3_HUMAN,tr|B1ALB4|B1ALB4_HUMAN" 5 1208.6605 2.44 80196 10355 2 1208.664122 605.3375 Protein SMG7 OS=Homo sapiens OX=9606 GN=SMG7 PE=1 SV=2 8.75 2057.2 - 428923 - - - 3.0381 - 2.135 0.352 - 372.8 1 2 0 0.0037 11 0 0 0 1.53E+07 6.27E+06 - - - 3.6916 1 221125_WJC_METTL3_EV_vs_WT_F06.10358.10358.2 1.40E-05 14/26 R.SLLEGEGSSGGGGR.G "sp|P13645|K1C10_HUMAN,tr|A0A1B0GVI3|A0A1B0GVI3_HUMAN" 2 1261.5899 999 80197 10358 2 1261.589415 631.8022 "Keratin, type I cytoskeletal 10 OS=Homo sapiens OX=9606 GN=KRT10 PE=1 SV=6" 4.53 2057.6 - 1.64E+07 - - - -0.3511 - 2.701 0.602 - 654.7 1 2 0 -0.0004 14 0 0 0 9.46E+08 0.00E+00 - - - 5.9807 0.9899 221125_WJC_METTL3_EV_vs_WT_F06.10361.10361.2 0.000238 16/22 F.SSGSAVVSGGSR.R sp|P35908|K22E_HUMAN 1 1049.5102 32.23 80200 10361 2 1049.511808 525.7624 "Keratin, type II cytoskeletal 2 epidermal OS=Homo sapiens OX=9606 GN=KRT2 PE=1 SV=2" 9.47 2058 - 733183 - - - 1.5788 - 2.709 0.498 - 1015.8 1 1 0 0.0017 12 0 0 0 1.77E+07 5.50E+05 - - - 5.3409 0.9964 221125_WJC_METTL3_EV_vs_WT_F06.10365.10365.2 4.98E-05 18-Aug K.EFFNGKEPSR.G "sp|P11021|BIP_HUMAN,tr|A0A7P0TB36|A0A7P0TB36_HUMAN,tr|A0A7P0TAI0|A0A7P0TAI0_HUMAN" 3 1209.5778 0.64 80204 10365 2 1209.579054 605.7962 Endoplasmic reticulum chaperone BiP OS=Homo sapiens OX=9606 GN=HSPA5 PE=1 SV=2 6.24 2058.5 - 354369 - - - 1.007 - 1.606 0.467 - 238.3 1 2 1 0.0012 10 0 0 0 1.36E+07 2.13E+07 - - - 3.8123 1 221125_WJC_METTL3_EV_vs_WT_F06.10368.10368.3 1.47E-06 13/48 K.VVTKPGHIINPIK.A sp|Q9BVJ6|UT14A_HUMAN 1 1414.866 1.74 80205 10368 3 1414.86625 472.6293 U3 small nucleolar RNA-associated protein 14 homolog A OS=Homo sapiens OX=9606 GN=UTP14A PE=1 SV=1 10 2058.9 - 1.91E+06 - - - 0.1626 - 2.452 0.486 - 122.8 1 2 0 0.0002 13 0 0 0 3.53E+07 2.03E+07 - - - 6.3901 0.9923 221125_WJC_METTL3_EV_vs_WT_F06.10369.10369.2 6.11E-05 22-Oct Q.NVFPQSDGDSSK[136.11].V "sp|O95757|HS74L_HUMAN,tr|D6RJ96|D6RJ96_HUMAN,tr|E9PDE8|E9PDE8_HUMAN" 3 1287.5823 0 80206 10369 2 1287.582403 644.7984 Heat shock 70 kDa protein 4L OS=Homo sapiens OX=9606 GN=HSPA4L PE=1 SV=3 4.21 2059.1 - 759459 - - - 0.1111 - 1.984 0.53 - 273.5 1 1 0 0.0001 12 0 0 0 1.15E+05 2.36E+07 - - - 4.7582 0.9915 221125_WJC_METTL3_EV_vs_WT_F06.10370.10370.3 0.00191 Dec-48 K.VVTK[136.11]PGHIINPIK[136.11].A sp|Q9BVJ6|UT14A_HUMAN 1 1430.8944 1.74 80207 10370 3 1430.894072 477.9721 U3 small nucleolar RNA-associated protein 14 homolog A OS=Homo sapiens OX=9606 GN=UTP14A PE=1 SV=1 10 2059.1 - 1.38E+06 - - - -0.2432 - 2.08 0.136 - 87.3 2 2 0 -0.0003 13 0 0 0 3.53E+07 2.03E+07 - - - 1.9025 0.8826 221125_WJC_METTL3_EV_vs_WT_F06.10371.10371.3 0.00159 Nov-40 N.VKVDPEIQNVK.A sp|P35908|K22E_HUMAN 1 1267.7136 119.81 80208 10371 3 1267.712908 423.5785 "Keratin, type II cytoskeletal 2 epidermal OS=Homo sapiens OX=9606 GN=KRT2 PE=1 SV=2" 6.04 2059.2 - 807557 - - - -0.5474 - 2.48 0.285 - 180.3 1 1 1 -0.0007 11 0 0 0 1.94E+08 1.62E+06 - - - 4.2975 1 221125_WJC_METTL3_EV_vs_WT_F06.10375.10375.3 1.70E-05 17/44 R.IIAHAQLLEQHR[166.11].G "sp|P27708|PYR1_HUMAN,tr|F8VPD4|F8VPD4_HUMAN" 2 1437.808 0.47 80210 10375 3 1437.805174 480.2766 CAD protein OS=Homo sapiens OX=9606 GN=CAD PE=1 SV=3 6.92 2059.7 - 1.34E+06 - - - -1.9662 - 2.946 0.49 - 422.1 1 2 0 -0.0028 12 0 0 0 1.19E+07 2.52E+07 - - - 6.9971 0.9998 221125_WJC_METTL3_EV_vs_WT_F06.10376.10376.2 0.000292 20-Sep R.VEIIANDQGNR[166.11].L "sp|P11021|BIP_HUMAN,sp|P48741|HSP77_HUMAN,sp|P54652|HSP72_HUMAN,sp|P0DMV8|HS71A_HUMAN,sp|P34931|HS71L_HUMAN,sp|P11142|HSP7C_HUMAN,sp|P0DMV9|HS71B_HUMAN,sp|P17066|HSP76_HUMAN,tr|E9PQQ4|E9PQQ4_HUMAN,tr|E9PNE6|E9PNE6_HUMAN,tr|E9PKE3|E9PKE3_HUMAN,tr|A0A7P0TB36|A0A7P0TB36_HUMAN,tr|E9PLF4|E9PLF4_HUMAN,tr|A0A7P0TAI0|A0A7P0TAI0_HUMAN,tr|Q53FA3|Q53FA3_HUMAN,tr|E9PI65|E9PI65_HUMAN,tr|E9PK54|E9PK54_HUMAN,tr|E9PN25|E9PN25_HUMAN,tr|E9PPY6|E9PPY6_HUMAN,tr|E9PQK7|E9PQK7_HUMAN,tr|A0A0G2JIW1|A0A0G2JIW1_HUMAN" 21 1237.629 0.16 80211 10376 2 1237.629072 619.8218 Endoplasmic reticulum chaperone BiP OS=Homo sapiens OX=9606 GN=HSPA5 PE=1 SV=2 4.37 2059.9 - 1.16E+06 - - - 0.0307 - 1.99 0.399 - 244.6 1 2 0 0 11 0 0 0 1.44E+08 8.96E+08 - - - 3.8496 0.9999 221125_WJC_METTL3_EV_vs_WT_F06.10377.10377.3 1.14E-05 13/44 R.TNVVTMPTAHPR[166.11].L "sp|Q13428|TCOF_HUMAN,tr|E7ETY2|E7ETY2_HUMAN,tr|A0A3B3IS06|A0A3B3IS06_HUMAN,tr|A0A6I8PRA0|A0A6I8PRA0_HUMAN" 4 1332.6848 0.45 80212 10377 3 1332.68675 445.2355 Treacle protein OS=Homo sapiens OX=9606 GN=TCOF1 PE=1 SV=3 9.44 2059.9 - 1.49E+06 - - - 1.482 - 2.519 0.429 - 309 1 2 0 0.002 12 0 0 0 3.57E+07 7.97E+07 - - - 5.8832 0.999 221125_WJC_METTL3_EV_vs_WT_F06.10378.10378.3 0.0116 Dec-44 R.TNVVTMPTAHPR.L "sp|Q13428|TCOF_HUMAN,tr|E7ETY2|E7ETY2_HUMAN,tr|A0A3B3IS06|A0A3B3IS06_HUMAN,tr|A0A6I8PRA0|A0A6I8PRA0_HUMAN" 4 1322.6765 0.44 80213 10378 3 1322.674866 441.8994 Treacle protein OS=Homo sapiens OX=9606 GN=TCOF1 PE=1 SV=3 9.44 2060 - 2.05E+06 - - - -1.2392 - 1.85 0.283 - 142 1 2 0 -0.0016 12 0 0 0 3.52E+07 7.97E+07 - - - 3.3999 0.9993 221125_WJC_METTL3_EV_vs_WT_F06.10382.10382.2 0.000726 18-Nov R.EHVLELENSK[136.11].G "sp|Q92667|AKAP1_HUMAN,tr|I3L0W0|I3L0W0_HUMAN" 2 1204.6179 1.39 80217 10382 2 1204.621014 603.3162 "A-kinase anchor protein 1, mitochondrial OS=Homo sapiens OX=9606 GN=AKAP1 PE=1 SV=1" 4.75 2060.4 - 315227 - - - 2.5709 - 2.236 0.369 - 511.4 1 2 0 0.0031 10 0 0 0 6.79E+06 4.88E+06 - - - 4.0116 0.9997 221125_WJC_METTL3_EV_vs_WT_F06.10385.10385.3 6.61E-05 Dec-36 K.STFREESPLR.L "sp|Q9NYF8|BCLF1_HUMAN,tr|E9PKI6|E9PKI6_HUMAN,tr|A0A1W2PQ43|A0A1W2PQ43_HUMAN,tr|E9PK91|E9PK91_HUMAN,tr|E9PJA7|E9PJA7_HUMAN,tr|E9PK09|E9PK09_HUMAN,tr|E9PQN2|E9PQN2_HUMAN" 7 1220.6149 2.37 80218 10385 3 1220.614911 407.8789 Bcl-2-associated transcription factor 1 OS=Homo sapiens OX=9606 GN=BCLAF1 PE=1 SV=2 5.86 2060.8 - 1.35E+06 - - - -0.032 - 2.189 0.44 - 280.3 1 2 1 0 10 0 0 0 3.52E+08 1.48E+08 - - - 5.7336 0.9997 221125_WJC_METTL3_EV_vs_WT_F06.10388.10388.3 0.0112 Oct-48 R.ATFVSSVRPESSR.L "sp|Q4KMQ1|TPRN_HUMAN,tr|H3BLU1|H3BLU1_HUMAN" 2 1421.7263 2.52 80221 10388 3 1421.725721 474.916 Taperin OS=Homo sapiens OX=9606 GN=TPRN PE=1 SV=2 9.64 2061 - 1.28E+06 - - - -0.4016 - 1.708 0.371 - 141.5 1 2 0 -0.0006 13 0 0 0 2.28E+07 9.03E+06 - - - 4.1275 0.9985 221125_WJC_METTL3_EV_vs_WT_F06.10390.10390.3 0.279 Dec-52 K.IGSVAPDTINNHVK.T sp|Q9UHY1|NRBP_HUMAN 1 1463.7732 1.34 80223 10390 3 1463.774336 488.9317 Nuclear receptor-binding protein OS=Homo sapiens OX=9606 GN=NRBP1 PE=1 SV=1 6.74 2061.3 - 633771 - - - 0.7474 - 2.024 0.234 - 180.4 1 2 0 0.0011 14 0 0 0 8.47E+06 6.34E+06 - - - 3.0223 1 221125_WJC_METTL3_EV_vs_WT_F06.10391.10391.2 5.68E-05 14/18 K.KGDEC[160.03]ELLGH.S sp|P49411|EFTU_HUMAN 1 1156.5183 1.84 80224 10391 2 1156.515965 579.2664 "Elongation factor Tu, mitochondrial OS=Homo sapiens OX=9606 GN=TUFM PE=1 SV=2" 4.65 2061.4 - 457495 - - - -1.9956 - 2.879 0.602 - 641.9 1 1 0 -0.0023 10 0 0 0 1.51E+07 8.23E+06 - - - 6.4383 0.8867 221125_WJC_METTL3_EV_vs_WT_F06.10396.10396.2 1.02 20-Aug K.K[136.11]SSGGSVTLSK[136.11].S "sp|Q8N7N1|F86B1_HUMAN,tr|E9PQV7|E9PQV7_HUMAN,tr|E9PPT9|E9PPT9_HUMAN,tr|H0YD24|H0YD24_HUMAN" 4 1065.6001 0.01 80227 10396 2 1065.593479 533.8073 Putative protein N-methyltransferase FAM86B1 OS=Homo sapiens OX=9606 GN=FAM86B1 PE=2 SV=2 10 2062.1 - 1.04E+06 - - - -6.2021 - 1.847 0.129 - 181.2 2 2 0 -0.0066 11 0 0 0 1.48E+06 1.41E+08 - - - 1.5171 1 221125_WJC_METTL3_EV_vs_WT_F06.10397.10397.2 3.82E-05 13/22 K.NQNSWGTGEDVK.V sp|P20700|LMNB1_HUMAN 1 1333.5899 2.42 80228 10397 2 1333.586907 667.8022 Lamin-B1 OS=Homo sapiens OX=9606 GN=LMNB1 PE=1 SV=2 4.37 2062.2 - 962246 - - - -2.2128 - 2.491 0.588 - 663.3 1 2 0 -0.003 12 0 0 0 1.53E+08 6.31E+07 - - - 5.7845 0.9999 221125_WJC_METTL3_EV_vs_WT_F06.10401.10401.3 9.03E-05 Dec-44 R.ISVYYNEASSHK.Y "sp|Q13509|TBB3_HUMAN,tr|A0A0B4J269|A0A0B4J269_HUMAN,tr|G3V3R4|G3V3R4_HUMAN,tr|G3V5W4|G3V5W4_HUMAN,tr|G3V2R8|G3V2R8_HUMAN,tr|G3V2N6|G3V2N6_HUMAN" 6 1396.6623 1.29 80232 10401 3 1396.664022 466.5614 Tubulin beta-3 chain OS=Homo sapiens OX=9606 GN=TUBB3 PE=1 SV=2 6.75 2062.6 - 636310 - - - 1.2372 - 2.019 0.452 - 146.5 1 2 0 0.0017 12 0 0 0 2.63E+07 2.03E+07 - - - 5.5264 1 221125_WJC_METTL3_EV_vs_WT_F06.10403.10403.2 1.27E-08 22-Dec K.ILC[160.03]EQC[160.03]MTSNQK[136.11].K "sp|Q8WXI9|P66B_HUMAN,tr|A0A0U1RRM1|A0A0U1RRM1_HUMAN,tr|A0A0U1RR30|A0A0U1RR30_HUMAN" 3 1518.672 2.35 80234 10403 2 1518.669535 760.3433 Transcriptional repressor p66-beta OS=Homo sapiens OX=9606 GN=GATAD2B PE=1 SV=1 5.99 2062.9 - 376050 - - - -1.6363 - 2.463 0.696 - 510.5 1 2 0 -0.0025 12 0 0 0 1.55E+08 6.60E+07 - - - 6.5526 1 221125_WJC_METTL3_EV_vs_WT_F06.10404.10404.2 8.01E-07 Dec-32 R.LVAGEMGQNEPDQGGQR[166.11].G "sp|Q99714|HCD2_HUMAN,tr|Q5H928|Q5H928_HUMAN,tr|A0A804HHW5|A0A804HHW5_HUMAN" 3 1794.8194 0.72 80235 10404 2 1794.816973 898.417 3-hydroxyacyl-CoA dehydrogenase type-2 OS=Homo sapiens OX=9606 GN=HSD17B10 PE=1 SV=3 4.14 2063 - 358793 - - - -1.3689 - 2.5 0.627 - 286.1 1 2 0 -0.0025 17 0 0 0 8.74E+06 1.21E+07 - - - 5.924 1 221125_WJC_METTL3_EV_vs_WT_F06.10408.10408.3 3.21E-05 Dec-40 K.ASIHEAWTDGK.E "sp|O43707|ACTN4_HUMAN,sp|P12814|ACTN1_HUMAN,tr|A0A804HK61|A0A804HK61_HUMAN,tr|A0A804HJU8|A0A804HJU8_HUMAN,tr|A0A804HIN7|A0A804HIN7_HUMAN,tr|H9KV75|H9KV75_HUMAN,tr|A0A804HLF4|A0A804HLF4_HUMAN,tr|A0A804HII9|A0A804HII9_HUMAN,tr|A0A804HL31|A0A804HL31_HUMAN,tr|F5GXS2|F5GXS2_HUMAN,tr|A0A804HLD0|A0A804HLD0_HUMAN,tr|H7C144|H7C144_HUMAN" 12 1213.5728 1.87 80237 10408 3 1213.571174 405.5315 Alpha-actinin-4 OS=Homo sapiens OX=9606 GN=ACTN4 PE=1 SV=2 5.32 2063.5 - 1.99E+06 - - - -1.2995 - 2.61 0.502 - 248.4 1 2 0 -0.0016 11 0 0 0 1.67E+08 8.94E+07 - - - 6.8617 1 221125_WJC_METTL3_EV_vs_WT_F06.10410.10410.2 0.000307 14/22 K.ILC[160.03]EQC[160.03]MTSNQK.K "sp|Q8WXI9|P66B_HUMAN,tr|A0A0U1RRM1|A0A0U1RRM1_HUMAN,tr|A0A0U1RR30|A0A0U1RR30_HUMAN" 3 1510.6578 2.35 80239 10410 2 1510.657456 756.3362 Transcriptional repressor p66-beta OS=Homo sapiens OX=9606 GN=GATAD2B PE=1 SV=1 5.99 2063.8 - 1.94E+06 - - - -0.241 - 2.544 0.583 - 780.3 1 2 0 -0.0004 12 0 0 0 1.55E+08 6.60E+07 - - - 5.8037 0.9997 221125_WJC_METTL3_EV_vs_WT_F06.10411.10411.2 0.457 22-Dec K.NQNSWGTGEDVK[136.11].V sp|P20700|LMNB1_HUMAN 1 1341.6041 2.42 80240 10411 2 1341.602094 671.8093 Lamin-B1 OS=Homo sapiens OX=9606 GN=LMNB1 PE=1 SV=2 4.37 2063.8 - 1.58E+06 - - - -1.4639 - 2.187 0.392 - 369.9 1 2 0 -0.002 12 0 0 0 1.53E+08 6.31E+07 - - - 3.9947 0.9968 221125_WJC_METTL3_EV_vs_WT_F06.10412.10412.3 8.96E-06 13/36 R.RDPYGFGDSR.D sp|Q9HCD5|NCOA5_HUMAN 1 1168.5261 1.64 80241 10412 3 1168.525869 390.516 Nuclear receptor coactivator 5 OS=Homo sapiens OX=9606 GN=NCOA5 PE=1 SV=2 5.96 2063.9 - 1.21E+06 - - - -0.2276 - 2.005 0.175 - 269 1 2 0 -0.0003 10 0 0 0 1.39E+08 8.47E+07 - - - 2.5226 1 221125_WJC_METTL3_EV_vs_WT_F06.10414.10414.3 1.35E-05 20/56 K.AEVTMGDPHQQTLAR[166.11].L "sp|Q13769|THOC5_HUMAN,tr|H7C072|H7C072_HUMAN,tr|F8WCP5|F8WCP5_HUMAN,tr|C9JXG5|C9JXG5_HUMAN,tr|H7C441|H7C441_HUMAN" 5 1662.8023 0.8 80243 10414 3 1662.802712 555.2747 THO complex subunit 5 homolog OS=Homo sapiens OX=9606 GN=THOC5 PE=1 SV=2 5.32 2064.1 - 1.05E+06 - - - 0.2333 - 3.232 0.558 - 630.6 1 2 0 0.0004 15 0 0 0 1.65E+07 2.06E+07 - - - 7.8221 0.9996 221125_WJC_METTL3_EV_vs_WT_F06.10415.10415.3 0.000719 Sep-52 R.VTVDNQGEK[136.11]PVLVK[136.11].T sp|Q9P215|POGK_HUMAN 1 1540.8796 0.89 80244 10415 3 1540.876775 514.6338 Pogo transposable element with KRAB domain OS=Homo sapiens OX=9606 GN=POGK PE=1 SV=2 6.04 2064.3 - 918862 - - - -1.8061 - 1.826 0.371 - 76.8 1 2 0 -0.0028 14 0 0 0 9.70E+06 1.08E+07 - - - 4.2757 0.9992 221125_WJC_METTL3_EV_vs_WT_F06.10416.10416.2 1.35E-05 28-Nov R.VTSGGVSESPSGFSK[136.11].H "sp|O14757|CHK1_HUMAN,tr|E7EPP6|E7EPP6_HUMAN" 2 1432.6925 0.29 80245 10416 2 1432.697972 717.3535 Serine\threonine-protein kinase Chk1 OS=Homo sapiens OX=9606 GN=CHEK1 PE=1 SV=2 5.97 2064.4 - 753672 - - - 3.7929 - 2.724 0.526 - 223.1 1 2 0 0.0054 15 0 0 0 5.03E+06 1.76E+07 - - - 5.388 0.9775 221125_WJC_METTL3_EV_vs_WT_F06.10424.10424.2 0.259 18-Oct K.STFREESPLR.L "sp|Q9NYF8|BCLF1_HUMAN,tr|E9PKI6|E9PKI6_HUMAN,tr|A0A1W2PQ43|A0A1W2PQ43_HUMAN,tr|E9PK91|E9PK91_HUMAN,tr|E9PJA7|E9PJA7_HUMAN,tr|E9PK09|E9PK09_HUMAN,tr|E9PQN2|E9PQN2_HUMAN" 7 1220.6149 0.7 80251 10424 2 1220.617265 611.3148 Bcl-2-associated transcription factor 1 OS=Homo sapiens OX=9606 GN=BCLAF1 PE=1 SV=2 5.86 2065.4 - 941578 - - - 1.8966 - 1.827 0.23 - 163.6 1 2 1 0.0023 10 0 0 0 8.47E+07 1.22E+08 - - - 2.4213 0.9997 221125_WJC_METTL3_EV_vs_WT_F06.10425.10425.2 0.239 18-Nov R.RDPYGFGDSR.D sp|Q9HCD5|NCOA5_HUMAN 1 1168.5261 1.51 80252 10425 2 1168.526854 585.2703 Nuclear receptor coactivator 5 OS=Homo sapiens OX=9606 GN=NCOA5 PE=1 SV=2 5.96 2065.5 - 805928 - - - 0.6153 - 2.165 0.364 - 375.7 1 2 0 0.0007 10 0 0 0 9.49E+07 6.29E+07 - - - 3.8853 0.9999 221125_WJC_METTL3_EV_vs_WT_F06.10428.10428.2 2.80E-05 14/20 K.ASIHEAWTDGK.E "sp|O43707|ACTN4_HUMAN,sp|P12814|ACTN1_HUMAN,tr|A0A804HK61|A0A804HK61_HUMAN,tr|A0A804HJU8|A0A804HJU8_HUMAN,tr|A0A804HIN7|A0A804HIN7_HUMAN,tr|H9KV75|H9KV75_HUMAN,tr|A0A804HLF4|A0A804HLF4_HUMAN,tr|A0A804HII9|A0A804HII9_HUMAN,tr|A0A804HL31|A0A804HL31_HUMAN,tr|F5GXS2|F5GXS2_HUMAN,tr|A0A804HLD0|A0A804HLD0_HUMAN,tr|H7C144|H7C144_HUMAN" 12 1213.5728 4.28 80253 10428 2 1213.571679 607.7937 Alpha-actinin-4 OS=Homo sapiens OX=9606 GN=ACTN4 PE=1 SV=2 5.32 2065.9 - 1.60E+06 - - - -0.8833 - 2.564 0.535 - 732.9 1 2 0 -0.0011 11 0 0 0 3.30E+07 7.70E+06 - - - 5.5393 0.9999 221125_WJC_METTL3_EV_vs_WT_F06.10430.10430.2 0.00443 13/22 K.ASSEGTIPQVQR.E sp|Q9BVJ6|UT14A_HUMAN 1 1271.647 1.35 80254 10430 2 1271.647087 636.8308 U3 small nucleolar RNA-associated protein 14 homolog A OS=Homo sapiens OX=9606 GN=UTP14A PE=1 SV=1 6.05 2066.1 - 1.48E+06 - - - 0.0849 - 2.494 0.44 - 433.6 1 2 0 0.0001 12 0 0 0 1.42E+08 1.05E+08 - - - 4.6954 0.9954 221125_WJC_METTL3_EV_vs_WT_F06.10433.10433.3 0.00522 Sep-48 K.IAGLYNDSEPPRK.T sp|Q96ES7|SGF29_HUMAN 1 1458.7467 1.16 80257 10433 3 1458.741704 487.2562 SAGA-associated factor 29 OS=Homo sapiens OX=9606 GN=SGF29 PE=1 SV=1 6.07 2066.4 - 566282 - - - -3.4201 - 1.839 0.299 - 55.2 2 2 0 -0.005 13 0 0 0 9.92E+06 8.56E+06 - - - 3.3846 0.8234 221125_WJC_METTL3_EV_vs_WT_F06.10436.10436.2 0.0579 13/20 N.VKVDPEIQNVK.A sp|P35908|K22E_HUMAN 1 1267.7136 999 80258 10436 2 1267.712345 634.8641 "Keratin, type II cytoskeletal 2 epidermal OS=Homo sapiens OX=9606 GN=KRT2 PE=1 SV=2" 6.04 2066.8 - 2.16E+06 - - - -0.9915 - 2.243 0.337 - 375.7 1 1 1 -0.0013 11 0 0 0 5.23E+07 0.00E+00 - - - 3.715 0.9999 221125_WJC_METTL3_EV_vs_WT_F06.10440.10440.2 9.83E-05 14/24 R.QALQSTPLGSSSK[136.11].S "sp|O15027|SC16A_HUMAN,tr|F1T0I1|F1T0I1_HUMAN" 2 1310.6921 0.87 80262 10440 2 1310.693467 656.3533 Protein transport protein Sec16A OS=Homo sapiens OX=9606 GN=SEC16A PE=1 SV=4 8.75 2067.2 - 937167 - - - 1.0086 - 2.724 0.487 - 722 1 2 0 0.0013 13 0 0 0 1.87E+07 2.14E+07 - - - 5.2095 0.8736 221125_WJC_METTL3_EV_vs_WT_F06.10450.10450.3 0.000192 13/36 K.QR[166.11]YPDGIISK[136.11].P sp|Q86U44|MTA70_HUMAN 1 1193.6523 0.02 80269 10450 3 1193.653395 398.8914 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 8.59 2068.3 - 1.03E+09 - - - 0.8822 - 2.161 0.312 - 299.9 1 1 1 0.0011 10 0 0 0 6.07E+08 3.75E+10 - - - 4.2686 0.9996 221125_WJC_METTL3_EV_vs_WT_F06.10452.10452.2 0.00181 20-Nov R.VEIIANDQGNR.L "sp|P11021|BIP_HUMAN,sp|P48741|HSP77_HUMAN,sp|P54652|HSP72_HUMAN,sp|P0DMV8|HS71A_HUMAN,sp|P34931|HS71L_HUMAN,sp|P11142|HSP7C_HUMAN,sp|P0DMV9|HS71B_HUMAN,sp|P17066|HSP76_HUMAN,tr|E9PQQ4|E9PQQ4_HUMAN,tr|E9PNE6|E9PNE6_HUMAN,tr|E9PKE3|E9PKE3_HUMAN,tr|A0A7P0TB36|A0A7P0TB36_HUMAN,tr|E9PLF4|E9PLF4_HUMAN,tr|A0A7P0TAI0|A0A7P0TAI0_HUMAN,tr|Q53FA3|Q53FA3_HUMAN,tr|E9PI65|E9PI65_HUMAN,tr|E9PK54|E9PK54_HUMAN,tr|E9PN25|E9PN25_HUMAN,tr|E9PPY6|E9PPY6_HUMAN,tr|E9PQK7|E9PQK7_HUMAN,tr|A0A0G2JIW1|A0A0G2JIW1_HUMAN" 21 1227.6208 0.16 80270 10452 2 1227.621313 614.8177 Endoplasmic reticulum chaperone BiP OS=Homo sapiens OX=9606 GN=HSPA5 PE=1 SV=2 4.37 2068.6 - 6.45E+06 - - - 0.4472 - 2.263 0.299 - 441 1 2 0 0.0005 11 0 0 0 1.44E+08 8.94E+08 - - - 3.4586 1 221125_WJC_METTL3_EV_vs_WT_F06.10455.10455.2 3.55E-09 16/30 R.VAGTQAC[160.03]ATETIDTSR[166.11].V sp|Q9BRR6|ADPGK_HUMAN 1 1689.7867 0.99 80273 10455 2 1689.784782 845.9006 ADP-dependent glucokinase OS=Homo sapiens OX=9606 GN=ADPGK PE=1 SV=1 4.37 2068.9 - 1.28E+06 - - - -1.1552 - 3.203 0.666 - 677.6 1 2 0 -0.002 16 0 0 0 1.23E+08 1.25E+08 - - - 6.8214 1 221125_WJC_METTL3_EV_vs_WT_F06.10456.10456.2 1.58E-08 20-Dec K.YTAC[160.03]LC[160.03]DDNPK.T sp|P12273|PIP_HUMAN 1 1355.5486 999 80274 10456 2 1355.545998 678.7816 Prolactin-inducible protein OS=Homo sapiens OX=9606 GN=PIP PE=1 SV=1 4.21 2069 - 1.10E+06 - - - -1.9099 - 2.186 0.684 - 547.4 1 2 0 -0.0026 11 0 0 0 1.11E+08 0.00E+00 - - - 6.2079 0.9999 221125_WJC_METTL3_EV_vs_WT_F06.10461.10461.2 3.98E-05 20-Oct R.DSYDSYATHNE.- sp|Q14011|CIRBP_HUMAN 1 1300.4844 - 80277 10461 2 1300.483764 651.2495 Cold-inducible RNA-binding protein OS=Homo sapiens OX=9606 GN=CIRBP PE=1 SV=1 4.31 2069.6 - 7.78E+06 - - - -0.4814 - 2.061 0.614 - 210 1 2 0 -0.0006 11 0 0 0 - - - - - 5.5322 0.9996 221125_WJC_METTL3_EV_vs_WT_F06.10468.10468.2 0.000189 14-Sep K.HVVFIAQR[166.11].R "sp|P62081|RS7_HUMAN,tr|B5MCP9|B5MCP9_HUMAN,tr|A0A2R8Y623|A0A2R8Y623_HUMAN" 3 978.5639 0.38 80281 10468 2 978.563234 490.2892 40S ribosomal protein S7 OS=Homo sapiens OX=9606 GN=RPS7 PE=1 SV=1 9.76 2070.6 - 621852 - - - -0.6346 - 1.519 0.401 - 300.8 1 2 0 -0.0006 8 0 0 0 5.27E+06 1.37E+07 - - - 3.2634 1 221125_WJC_METTL3_EV_vs_WT_F06.10478.10478.2 2.73E-10 17/30 R.VAGTQAC[160.03]ATETIDTSR.V sp|Q9BRR6|ADPGK_HUMAN 1 1679.7785 0.99 80287 10478 2 1679.776943 840.8965 ADP-dependent glucokinase OS=Homo sapiens OX=9606 GN=ADPGK PE=1 SV=1 4.37 2071.7 - 2.94E+06 - - - -0.9055 - 2.837 0.685 - 313.7 1 2 0 -0.0015 16 0 0 0 1.23E+08 1.25E+08 - - - 6.6636 0.9989 221125_WJC_METTL3_EV_vs_WT_F06.10479.10479.3 4.06E-05 16/52 R.FTSLDKGENGTLSR.E "sp|Q99653|CHP1_HUMAN,tr|F5GX29|F5GX29_HUMAN,tr|H0YKE7|H0YKE7_HUMAN,tr|H0YNG9|H0YNG9_HUMAN" 4 1523.758 1.7 80288 10479 3 1523.751704 508.9266 Calcineurin B homologous protein 1 OS=Homo sapiens OX=9606 GN=CHP1 PE=1 SV=3 6.07 2071.8 - 1.51E+06 - - - -4.1227 - 2.812 0.476 - 271.5 1 2 1 -0.0063 14 0 0 0 3.96E+07 2.32E+07 - - - 6.5928 1 221125_WJC_METTL3_EV_vs_WT_F06.10480.10480.2 4.09E-08 16-Oct L.GNDFHTNK[136.11]R[166.11].V "sp|P08708|RS17_HUMAN,tr|H0YN73|H0YN73_HUMAN,tr|H3BNC9|H3BNC9_HUMAN,tr|A0A0J9YYC4|A0A0J9YYC4_HUMAN,tr|H0YN88|H0YN88_HUMAN,tr|A0A075B716|A0A075B716_HUMAN" 6 1105.5384 1.58 80289 10480 2 1105.536829 553.7765 40S ribosomal protein S17 OS=Homo sapiens OX=9606 GN=RPS17 PE=1 SV=2 8.75 2071.9 - 1.45E+06 - - - -1.3984 - 2.144 0.611 - 551.9 1 1 0 -0.0015 9 0 0 0 2.81E+07 1.78E+07 - - - 5.7598 0.9972 221125_WJC_METTL3_EV_vs_WT_F06.10485.10485.3 0.00331 13/56 R.IAPR[166.11]PASGPIR[166.11]PIVR[166.11].C "sp|P26373|RL13_HUMAN,tr|J3QSB4|J3QSB4_HUMAN" 2 1628.9981 1.12 80291 10485 3 1628.994138 544.0066 60S ribosomal protein L13 OS=Homo sapiens OX=9606 GN=RPL13 PE=1 SV=4 12.3 2072.5 - 2.95E+06 - - - -2.4254 - 1.655 0.302 - 68.8 1 2 0 -0.004 15 0 0 0 1.10E+08 9.83E+07 - - - 3.2205 0.9975 221125_WJC_METTL3_EV_vs_WT_F06.10487.10487.3 0.00193 15/44 K.LAFQQKPPPPPK.K "sp|O76031|CLPX_HUMAN,tr|H0YM48|H0YM48_HUMAN" 2 1346.7711 1.5 80293 10487 3 1346.76543 449.931 "ATP-dependent Clp protease ATP-binding subunit clpX-like, mitochondrial OS=Homo sapiens OX=9606 GN=CLPX PE=1 SV=2" 10 2072.8 - 1.53E+06 - - - -4.1781 - 2.438 0.294 - 269 1 2 0 -0.0056 12 0 0 0 4.78E+07 3.19E+07 - - - 4.2865 0.998 221125_WJC_METTL3_EV_vs_WT_F06.10488.10488.3 0.0113 Dec-48 K.VQQAELHTGSLPR[166.11].L sp|Q13085|ACACA_HUMAN 1 1444.7662 0.78 80294 10488 3 1444.764569 482.596 Acetyl-CoA carboxylase 1 OS=Homo sapiens OX=9606 GN=ACACA PE=1 SV=2 6.72 2072.9 - 1.30E+06 - - - -1.1261 - 2.009 0.219 - 145.5 1 2 0 -0.0016 13 0 0 0 2.14E+07 2.74E+07 - - - 2.8727 1 221125_WJC_METTL3_EV_vs_WT_F06.10493.10493.2 1.07E-08 15/28 L.LEGGQEDFESSGAGK.L "sp|P35527|K1C9_HUMAN,tr|K7EQQ3|K7EQQ3_HUMAN" 2 1509.6583 3.38 80296 10493 2 1509.65394 755.8364 "Keratin, type I cytoskeletal 9 OS=Homo sapiens OX=9606 GN=KRT9 PE=1 SV=3" 4 2073.5 - 1.55E+06 - - - -2.9086 - 2.945 0.686 - 797.2 1 1 0 -0.0044 15 0 0 0 1.22E+08 3.59E+07 - - - 6.7619 0.9977 221125_WJC_METTL3_EV_vs_WT_F06.10507.10507.3 0.0395 13/40 K.QIEEINEQIR[166.11]K[136.11].E sp|Q99543|DNJC2_HUMAN 1 1416.7692 0.85 80305 10507 3 1416.766237 473.2637 DnaJ homolog subfamily C member 2 OS=Homo sapiens OX=9606 GN=DNAJC2 PE=1 SV=4 4.79 2075.2 - 1.16E+06 - - - -2.0653 - 1.906 0.25 - 174.5 1 2 0 -0.0029 11 0 0 0 2.14E+07 2.51E+07 - - - 3.1588 0.9908 221125_WJC_METTL3_EV_vs_WT_F06.10523.10523.3 0.0126 13/40 T.TFDLGGHEQAR.R "sp|Q9NR31|SAR1A_HUMAN,tr|Q5SQT8|Q5SQT8_HUMAN" 2 1229.5789 1.46 80314 10523 3 1229.579967 410.8669 GTP-binding protein SAR1a OS=Homo sapiens OX=9606 GN=SAR1A PE=1 SV=1 5.29 2077.1 - 932071 - - - 0.8686 - 2.442 0.384 - 205 1 1 0 0.0011 11 0 0 0 2.81E+07 1.93E+07 - - - 5.3573 0.9995 221125_WJC_METTL3_EV_vs_WT_F06.10524.10524.2 0.061 13/18 R.RQLDNIVGER.G sp|P04259|K2C6B_HUMAN 1 1198.6418 999 80315 10524 2 1198.639918 600.3282 "Keratin, type II cytoskeletal 6B OS=Homo sapiens OX=9606 GN=KRT6B PE=1 SV=5" 6.07 2077.1 - 1.03E+07 - - - -1.5985 - 2.403 0.282 - 280.4 1 2 0 -0.0019 10 0 0 0 2.23E+08 0.00E+00 - - - 3.5704 0.9997 221125_WJC_METTL3_EV_vs_WT_F06.10525.10525.2 0.00159 18-Dec R.YPDGIISK[136.11]PK[136.11].N sp|Q86U44|MTA70_HUMAN 1 1132.6463 0 80316 10525 2 1132.644541 567.3304 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 8.5 2077.3 - 1.06E+06 - - - -1.5618 - 2.029 0.432 - 412.5 1 2 0 -0.0018 10 0 0 0 6.81E+05 3.15E+09 - - - 4.2062 0.9999 221125_WJC_METTL3_EV_vs_WT_F06.10526.10526.3 1.03E-05 14/44 K.LAFQQK[136.11]PPPPPK[136.11].K "sp|O76031|CLPX_HUMAN,tr|H0YM48|H0YM48_HUMAN" 2 1362.7995 1.5 80317 10526 3 1362.797868 455.2738 "ATP-dependent Clp protease ATP-binding subunit clpX-like, mitochondrial OS=Homo sapiens OX=9606 GN=CLPX PE=1 SV=2" 10 2077.4 - 995097 - - - -1.166 - 2.741 0.38 - 302.2 1 2 0 -0.0016 12 0 0 0 4.47E+07 2.98E+07 - - - 5.5711 0.9976 221125_WJC_METTL3_EV_vs_WT_F06.10528.10528.3 1.76E-07 15/52 D.DAHPTLVTYADHSK[136.11].L "sp|Q86U44|MTA70_HUMAN,tr|F5H6D8|F5H6D8_HUMAN,tr|H0YFV6|H0YFV6_HUMAN,tr|B4DTN4|B4DTN4_HUMAN" 4 1561.7616 0.02 80318 10528 3 1561.760005 521.5945 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 5.98 2077.6 - 634283 - - - -1.0347 - 2.659 0.514 - 326.5 1 1 0 -0.0016 14 0 0 0 1.22E+06 7.71E+07 - - - 6.8691 0.9999 221125_WJC_METTL3_EV_vs_WT_F06.10532.10532.2 4.91E-05 24-Dec K.NSTFSASGETVER.K "sp|Q9BYP7|WNK3_HUMAN,tr|A0A087WYK2|A0A087WYK2_HUMAN,tr|B1AQN8|B1AQN8_HUMAN" 3 1383.6266 2.83 80321 10532 2 1383.625318 692.8206 Serine\threonine-protein kinase WNK3 OS=Homo sapiens OX=9606 GN=WNK3 PE=1 SV=3 4.53 2078.1 - 1.07E+06 - - - -0.9533 - 2.252 0.532 - 499.2 1 2 0 -0.0013 13 0 0 0 1.68E+07 5.94E+06 - - - 5.0535 0.9999 221125_WJC_METTL3_EV_vs_WT_F06.10536.10536.2 0.000545 18-Dec R.TNQELQEINR.V "sp|P07355|ANXA2_HUMAN,sp|A6NMY6|AXA2L_HUMAN,tr|H0YL33|H0YL33_HUMAN,tr|H0YMU9|H0YMU9_HUMAN,tr|H0YNA0|H0YNA0_HUMAN,tr|H0YMM1|H0YMM1_HUMAN,tr|H0YM50|H0YM50_HUMAN,tr|H0YMD0|H0YMD0_HUMAN,tr|H0YMW4|H0YMW4_HUMAN,tr|H0YLE2|H0YLE2_HUMAN,tr|H0YN42|H0YN42_HUMAN,tr|H0YN28|H0YN28_HUMAN,tr|A0A7I2V4P4|A0A7I2V4P4_HUMAN,tr|H0YNP5|H0YNP5_HUMAN,tr|H0YNB8|H0YNB8_HUMAN,tr|H0YKS4|H0YKS4_HUMAN" 16 1243.6157 9.52 80323 10536 2 1243.615479 622.8151 Annexin A2 OS=Homo sapiens OX=9606 GN=ANXA2 PE=1 SV=2 4.53 2078.5 - 3.10E+06 - - - -0.1608 - 2.556 0.44 - 926.2 1 2 0 -0.0002 10 0 0 0 3.12E+08 3.28E+07 - - - 4.9103 0.9987 221125_WJC_METTL3_EV_vs_WT_F06.10538.10538.3 0.000662 Oct-40 K.HPDADSLYVEK[136.11].L "sp|P54577|SYYC_HUMAN,tr|A0A6Q8PFX2|A0A6Q8PFX2_HUMAN" 2 1280.6128 0.7 80325 10538 3 1280.607846 427.8782 "Tyrosine--tRNA ligase, cytoplasmic OS=Homo sapiens OX=9606 GN=YARS1 PE=1 SV=4" 4.54 2078.7 - 628915 - - - -3.8934 - 1.809 0.398 - 140.9 1 2 0 -0.005 11 0 0 0 9.47E+06 1.34E+07 - - - 4.6599 0.9993 221125_WJC_METTL3_EV_vs_WT_F06.10539.10539.3 0.00826 Sep-40 K.HPDADSLYVEK.L "sp|P54577|SYYC_HUMAN,tr|A0A6Q8PFX2|A0A6Q8PFX2_HUMAN" 2 1272.5986 0.69 80326 10539 3 1272.597157 425.2068 "Tyrosine--tRNA ligase, cytoplasmic OS=Homo sapiens OX=9606 GN=YARS1 PE=1 SV=4" 4.54 2078.8 - 549869 - - - -1.159 - 1.709 0.322 - 101 1 2 0 -0.0015 11 0 0 0 1.03E+07 1.49E+07 - - - 3.652 1 221125_WJC_METTL3_EV_vs_WT_F06.10547.10547.2 0.000249 14/28 R.DPSASPGDAGEQAIR.Q sp|P18206|VINC_HUMAN 1 1469.6746 0.15 80332 10547 2 1469.669962 735.8446 Vinculin OS=Homo sapiens OX=9606 GN=VCL PE=1 SV=4 4.03 2079.9 - 744545 - - - -3.1898 - 2.757 0.578 - 423.6 1 2 0 -0.0047 15 0 0 0 1.51E+07 9.89E+07 - - - 5.802 1 221125_WJC_METTL3_EV_vs_WT_F06.10548.10548.2 4.59E-09 15/28 F.EQEMATAASSSSLEK.S "sp|Q6S8J3|POTEE_HUMAN,sp|P63261|ACTG_HUMAN,sp|P60709|ACTB_HUMAN,tr|A0A804GS07|A0A804GS07_HUMAN,tr|E7EVS6|E7EVS6_HUMAN,tr|A0A6Q8PFE4|A0A6Q8PFE4_HUMAN,tr|A0A2R8YEA7|A0A2R8YEA7_HUMAN,tr|A0A2R8Y793|A0A2R8Y793_HUMAN,tr|I3L4N8|I3L4N8_HUMAN" 9 1567.7036 1.08 80333 10548 2 1567.706228 784.8591 POTE ankyrin domain family member E OS=Homo sapiens OX=9606 GN=POTEE PE=2 SV=3 4.25 2080 - 567155 - - - 1.6974 - 2.854 0.683 - 714.6 1 1 0 0.0027 15 0 0 0 8.78E+06 8.10E+06 - - - 6.6631 1 221125_WJC_METTL3_EV_vs_WT_F06.10550.10550.2 1.85E-09 15/26 K.LGDEDEEIDGDTNK[136.11].Y "sp|P09884|DPOLA_HUMAN,tr|A6NMQ1|A6NMQ1_HUMAN" 2 1556.6569 0.37 80335 10550 2 1556.655001 779.3357 DNA polymerase alpha catalytic subunit OS=Homo sapiens OX=9606 GN=POLA1 PE=1 SV=2 3.62 2080.3 - 459003 - - - -1.2463 - 3.094 0.731 - 957.7 1 2 0 -0.0019 14 0 0 0 1.01E+06 2.71E+06 - - - 7.2739 0.9964 221125_WJC_METTL3_EV_vs_WT_F06.10554.10554.3 3.96E-05 14/40 T.TFDLGGHEQAR[166.11].R "sp|Q9NR31|SAR1A_HUMAN,tr|Q5SQT8|Q5SQT8_HUMAN" 2 1239.5872 1.5 80337 10554 3 1239.588401 414.203 GTP-binding protein SAR1a OS=Homo sapiens OX=9606 GN=SAR1A PE=1 SV=1 5.29 2080.7 - 1.18E+06 - - - 0.9939 - 2.452 0.481 - 341 1 1 0 0.0012 11 0 0 0 2.79E+07 1.86E+07 - - - 6.4503 0.9892 221125_WJC_METTL3_EV_vs_WT_F06.10555.10555.2 0.0196 16-Dec Y.PDGIISK[136.11]PK[136.11].N sp|Q86U44|MTA70_HUMAN 1 969.583 0 80338 10555 2 969.582442 485.7988 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 9.01 2080.9 - 2.21E+06 - - - -0.5569 - 2.312 0.379 - 432.4 1 1 0 -0.0005 9 0 0 0 2.43E+05 6.90E+08 - - - 4.2648 0.9986 221125_WJC_METTL3_EV_vs_WT_F06.10558.10558.2 0.00432 20-Oct R.R[166.11]ALELDGQSVK[136.11].A "sp|Q9UNE7|CHIP_HUMAN,tr|H3BS86|H3BS86_HUMAN" 2 1232.6844 0.04 80341 10558 2 1232.681648 617.3495 E3 ubiquitin-protein ligase CHIP OS=Homo sapiens OX=9606 GN=STUB1 PE=1 SV=2 6.07 2081.2 - 402876 - - - -2.2082 - 2.271 0.224 - 314.3 1 2 0 -0.0027 11 0 0 0 2.82E+05 6.80E+06 - - - 2.9135 0.9739 221125_WJC_METTL3_EV_vs_WT_F06.10559.10559.3 0.105 Dec-48 R.ALGGC[160.03]TR[166.11]PHVILR[166.11].E "sp|Q9NNW5|WDR6_HUMAN,tr|E9PBK6|E9PBK6_HUMAN,tr|E9PDU5|E9PDU5_HUMAN,tr|A0A087X295|A0A087X295_HUMAN" 4 1468.82 1.81 80342 10559 3 1468.816515 490.6139 WD repeat-containing protein 6 OS=Homo sapiens OX=9606 GN=WDR6 PE=1 SV=1 10.35 2081.3 - 400802 - - - -2.357 - 1.567 0.177 - 198.9 1 2 0 -0.0035 13 0 0 0 6.93E+06 3.83E+06 - - - 1.7302 0.999 221125_WJC_METTL3_EV_vs_WT_F06.10562.10562.2 0.00231 18-Oct R.TNQELQEINR[166.11].V "sp|P07355|ANXA2_HUMAN,sp|A6NMY6|AXA2L_HUMAN,tr|H0YL33|H0YL33_HUMAN,tr|H0YMU9|H0YMU9_HUMAN,tr|H0YNA0|H0YNA0_HUMAN,tr|H0YMM1|H0YMM1_HUMAN,tr|H0YM50|H0YM50_HUMAN,tr|H0YMD0|H0YMD0_HUMAN,tr|H0YMW4|H0YMW4_HUMAN,tr|H0YLE2|H0YLE2_HUMAN,tr|H0YN42|H0YN42_HUMAN,tr|H0YN28|H0YN28_HUMAN,tr|A0A7I2V4P4|A0A7I2V4P4_HUMAN,tr|H0YNP5|H0YNP5_HUMAN,tr|H0YNB8|H0YNB8_HUMAN,tr|H0YKS4|H0YKS4_HUMAN" 16 1253.6239 9.14 80343 10562 2 1253.626961 627.8193 Annexin A2 OS=Homo sapiens OX=9606 GN=ANXA2 PE=1 SV=2 4.53 2081.7 - 2.15E+06 - - - 2.4026 - 1.977 0.344 - 267.5 1 2 0 0.003 10 0 0 0 3.00E+08 3.28E+07 - - - 3.4833 0.9999 221125_WJC_METTL3_EV_vs_WT_F06.10563.10563.3 1.07E-05 13/52 R.DVLETEDEEPPPRR.W "sp|Q9ULV3|CIZ1_HUMAN,tr|Q5SYW2|Q5SYW2_HUMAN,tr|F5H2X7|F5H2X7_HUMAN,tr|H0Y5D5|H0Y5D5_HUMAN,tr|A0A0U1RQR2|A0A0U1RQR2_HUMAN,tr|A0A494C0L7|A0A494C0L7_HUMAN,tr|Q9BTG3|Q9BTG3_HUMAN" 7 1680.7955 8.35 80344 10563 3 1680.793197 561.2724 Cip1-interacting zinc finger protein OS=Homo sapiens OX=9606 GN=CIZ1 PE=1 SV=2 4.08 2081.8 - 1.32E+06 - - - -1.3666 - 2.33 0.432 - 227.9 1 2 0 -0.0023 14 0 0 0 3.21E+07 3.84E+06 - - - 5.6037 0.9999 221125_WJC_METTL3_EV_vs_WT_F06.10572.10572.2 2.63E-08 24-Oct R.NSEPAGLETPEAK[136.11].V "sp|P07814|SYEP_HUMAN,tr|V9GYZ6|V9GYZ6_HUMAN" 2 1349.6554 0.94 80352 10572 2 1349.656132 675.835 Bifunctional glutamate\proline--tRNA ligase OS=Homo sapiens OX=9606 GN=EPRS1 PE=1 SV=5 4.25 2082.9 - 2.02E+06 - - - 0.5238 - 2.244 0.606 - 380.9 1 2 0 0.0007 13 0 0 0 1.86E+08 1.98E+08 - - - 5.5911 0.9992 221125_WJC_METTL3_EV_vs_WT_F06.10575.10575.3 0.00124 18/48 R.FR[166.11]EALGDAQQSVR[166.11].L "sp|Q99615|DNJC7_HUMAN,tr|A0A6I8PR93|A0A6I8PR93_HUMAN,tr|K7ESP1|K7ESP1_HUMAN,tr|A0A6I8PRZ0|A0A6I8PRZ0_HUMAN,tr|A0A6I8PLE7|A0A6I8PLE7_HUMAN,tr|K7EJE9|K7EJE9_HUMAN,tr|A0A6I8PR89|A0A6I8PR89_HUMAN,tr|A0A6I8PIK4|A0A6I8PIK4_HUMAN,tr|K7ELJ8|K7ELJ8_HUMAN,tr|K7EN19|K7EN19_HUMAN,tr|A0A6I8PUC2|A0A6I8PUC2_HUMAN,tr|A0A6I8PS32|A0A6I8PS32_HUMAN,tr|K7EJL5|K7EJL5_HUMAN,tr|K7EPP7|K7EPP7_HUMAN,tr|A0A6I8PUD4|A0A6I8PUD4_HUMAN,tr|K7EIH8|K7EIH8_HUMAN,tr|K7ER44|K7ER44_HUMAN,tr|A0A6I8PU73|A0A6I8PU73_HUMAN,tr|K7EK03|K7EK03_HUMAN,tr|K7EJV7|K7EJV7_HUMAN,tr|A0A6I8PU89|A0A6I8PU89_HUMAN" 21 1495.7646 0.58 80355 10575 3 1495.764451 499.5955 DnaJ homolog subfamily C member 7 OS=Homo sapiens OX=9606 GN=DNAJC7 PE=1 SV=2 6.07 2083 - 1.70E+06 - - - -0.1197 - 2.867 0.292 - 717.8 1 2 1 -0.0002 13 0 0 0 2.96E+07 5.12E+07 - - - 4.6512 1 221125_WJC_METTL3_EV_vs_WT_F06.10576.10576.3 3.67E-05 16/56 K.AAGARPLTSPESLSR.D "sp|P46379|BAG6_HUMAN,tr|A0A7I2V508|A0A7I2V508_HUMAN,tr|A0A7P0MQS5|A0A7P0MQS5_HUMAN,tr|A0A024RCR6|A0A024RCR6_HUMAN,tr|A0A0G2JK23|A0A0G2JK23_HUMAN" 5 1511.8056 3.73 80356 10576 3 1511.80582 504.9425 Large proline-rich protein BAG6 OS=Homo sapiens OX=9606 GN=BAG6 PE=1 SV=2 9.64 2083.1 - 1.63E+06 - - - 0.1422 - 3.083 0.549 - 427.2 1 2 0 0.0002 15 0 0 0 3.07E+08 8.22E+07 - - - 7.5986 1 221125_WJC_METTL3_EV_vs_WT_F06.10583.10583.2 2.73E-09 13/24 R.GSSYGVTSTESYK.E sp|P98175|RBM10_HUMAN 1 1364.6096 2.53 80361 10583 2 1364.609593 683.3121 RNA-binding protein 10 OS=Homo sapiens OX=9606 GN=RBM10 PE=1 SV=3 6 2083.8 - 7.71E+06 - - - 0.0022 - 2.537 0.682 - 581.1 1 2 0 0 13 0 0 0 9.55E+07 3.78E+07 - - - 6.4676 0.9997 221125_WJC_METTL3_EV_vs_WT_F06.10585.10585.3 6.25E-05 15/48 R.FREALGDAQQSVR.L "sp|Q99615|DNJC7_HUMAN,tr|A0A6I8PR93|A0A6I8PR93_HUMAN,tr|K7ESP1|K7ESP1_HUMAN,tr|A0A6I8PRZ0|A0A6I8PRZ0_HUMAN,tr|A0A6I8PLE7|A0A6I8PLE7_HUMAN,tr|K7EJE9|K7EJE9_HUMAN,tr|A0A6I8PR89|A0A6I8PR89_HUMAN,tr|A0A6I8PIK4|A0A6I8PIK4_HUMAN,tr|K7ELJ8|K7ELJ8_HUMAN,tr|K7EN19|K7EN19_HUMAN,tr|A0A6I8PUC2|A0A6I8PUC2_HUMAN,tr|A0A6I8PS32|A0A6I8PS32_HUMAN,tr|K7EJL5|K7EJL5_HUMAN,tr|K7EPP7|K7EPP7_HUMAN,tr|A0A6I8PUD4|A0A6I8PUD4_HUMAN,tr|K7EIH8|K7EIH8_HUMAN,tr|K7ER44|K7ER44_HUMAN,tr|A0A6I8PU73|A0A6I8PU73_HUMAN,tr|K7EK03|K7EK03_HUMAN,tr|K7EJV7|K7EJV7_HUMAN,tr|A0A6I8PU89|A0A6I8PU89_HUMAN" 21 1475.7481 0.56 80363 10585 3 1475.750194 492.9233 DnaJ homolog subfamily C member 7 OS=Homo sapiens OX=9606 GN=DNAJC7 PE=1 SV=2 6.07 2084 - 1.33E+06 - - - 1.4257 - 2.683 0.424 - 444.9 1 2 1 0.0021 13 0 0 0 2.83E+07 5.02E+07 - - - 5.9425 0.9994 221125_WJC_METTL3_EV_vs_WT_F06.10587.10587.2 0.00316 16-Sep R.NVFHIASQK.N "sp|Q8N0T1|RBIS_HUMAN,tr|A0A087WWE7|A0A087WWE7_HUMAN,tr|E5RGR5|E5RGR5_HUMAN" 3 1042.556 1.84 80365 10587 2 1042.554352 522.2853 Ribosomal biogenesis factor OS=Homo sapiens OX=9606 GN=RBIS PE=1 SV=4 8.76 2084.3 - 714468 - - - -1.5606 - 1.733 0.365 - 262.2 1 2 0 -0.0016 9 0 0 0 3.22E+07 1.75E+07 - - - 3.3271 0.9999 221125_WJC_METTL3_EV_vs_WT_F06.10588.10588.3 1.28E-09 19/52 R.FNEVAAQYSEDK[136.11]AR[166.11].Q "sp|Q9Y237|PIN4_HUMAN,tr|A0A494C021|A0A494C021_HUMAN,tr|H0Y610|H0Y610_HUMAN,tr|H0Y4T6|H0Y4T6_HUMAN,tr|H0Y8P6|H0Y8P6_HUMAN,tr|J3KMW3|J3KMW3_HUMAN" 6 1644.7863 1.91 80366 10588 3 1644.783923 549.2694 Peptidyl-prolyl cis-trans isomerase NIMA-interacting 4 OS=Homo sapiens OX=9606 GN=PIN4 PE=1 SV=1 4.68 2084.4 - 640963 - - - -1.4263 - 3.323 0.519 - 456.8 1 2 1 -0.0023 14 0 0 0 1.33E+07 6.96E+06 - - - 7.517 0.9982 221125_WJC_METTL3_EV_vs_WT_F06.10589.10589.2 0.253 16-Sep R.NVFHIASQK[136.11].N "sp|Q8N0T1|RBIS_HUMAN,tr|A0A087WWE7|A0A087WWE7_HUMAN,tr|E5RGR5|E5RGR5_HUMAN" 3 1050.5702 1.84 80367 10589 2 1050.570634 526.2924 Ribosomal biogenesis factor OS=Homo sapiens OX=9606 GN=RBIS PE=1 SV=4 8.76 2084.5 - 574240 - - - 0.4331 - 1.426 0.25 - 242.7 1 2 0 0.0005 9 0 0 0 3.22E+07 1.75E+07 - - - 1.914 0.9998 221125_WJC_METTL3_EV_vs_WT_F06.10591.10591.2 0.000132 20-Nov K.HPDADSLYVEK.L "sp|P54577|SYYC_HUMAN,tr|A0A6Q8PFX2|A0A6Q8PFX2_HUMAN" 2 1272.5986 0.55 80369 10591 2 1272.596374 637.3066 "Tyrosine--tRNA ligase, cytoplasmic OS=Homo sapiens OX=9606 GN=YARS1 PE=1 SV=4" 4.54 2084.8 - 388480 - - - -1.7743 - 2.35 0.508 - 291 1 2 0 -0.0023 11 0 0 0 7.73E+06 1.41E+07 - - - 5.1038 0.9998 221125_WJC_METTL3_EV_vs_WT_F06.10592.10592.2 0.00014 20-Sep K.HPDADSLYVEK[136.11].L "sp|P54577|SYYC_HUMAN,tr|A0A6Q8PFX2|A0A6Q8PFX2_HUMAN" 2 1280.6128 0.57 80370 10592 2 1280.614555 641.3137 "Tyrosine--tRNA ligase, cytoplasmic OS=Homo sapiens OX=9606 GN=YARS1 PE=1 SV=4" 4.54 2084.9 - 372327 - - - 1.3454 - 2.079 0.489 - 205.4 1 2 0 0.0017 11 0 0 0 5.67E+06 9.98E+06 - - - 4.6321 1 221125_WJC_METTL3_EV_vs_WT_F06.10597.10597.3 4.81E-07 17/56 K.AAGAR[166.11]PLTSPESLSR[166.11].D "sp|P46379|BAG6_HUMAN,tr|A0A7I2V508|A0A7I2V508_HUMAN,tr|A0A7P0MQS5|A0A7P0MQS5_HUMAN,tr|A0A024RCR6|A0A024RCR6_HUMAN,tr|A0A0G2JK23|A0A0G2JK23_HUMAN" 5 1531.8221 3.94 80373 10597 3 1531.822465 511.6147 Large proline-rich protein BAG6 OS=Homo sapiens OX=9606 GN=BAG6 PE=1 SV=2 9.64 2085.4 - 2.01E+06 - - - 0.2089 - 3.133 0.455 - 429.7 1 2 0 0.0003 15 0 0 0 3.05E+08 7.75E+07 - - - 6.5926 1 221125_WJC_METTL3_EV_vs_WT_F06.10599.10599.3 1.27E-09 17/52 R.FNEVAAQYSEDKAR.Q "sp|Q9Y237|PIN4_HUMAN,tr|A0A494C021|A0A494C021_HUMAN,tr|H0Y610|H0Y610_HUMAN,tr|H0Y4T6|H0Y4T6_HUMAN,tr|H0Y8P6|H0Y8P6_HUMAN,tr|J3KMW3|J3KMW3_HUMAN" 6 1626.7638 1.91 80375 10599 3 1626.763037 543.2619 Peptidyl-prolyl cis-trans isomerase NIMA-interacting 4 OS=Homo sapiens OX=9606 GN=PIN4 PE=1 SV=1 4.68 2085.6 - 926209 - - - -0.4684 - 3.612 0.624 - 360.7 1 2 1 -0.0008 14 0 0 0 1.33E+07 6.96E+06 - - - 8.9097 0.9997 221125_WJC_METTL3_EV_vs_WT_F06.10608.10608.3 0.001 Dec-40 R.FRPLNESEVNR.G sp|P33176|KINH_HUMAN 1 1359.6895 1.48 80383 10608 3 1359.684538 454.2371 Kinesin-1 heavy chain OS=Homo sapiens OX=9606 GN=KIF5B PE=1 SV=1 6.14 2086.6 - 1.23E+06 - - - -3.6582 - 2.454 0.451 - 323.9 1 2 0 -0.005 11 0 0 0 2.21E+07 1.50E+07 - - - 6.1171 1 221125_WJC_METTL3_EV_vs_WT_F06.10610.10610.3 1.67E-05 Nov-40 R.HPGSFDVVHVK[136.11].D "sp|P62701|RS4X_HUMAN,sp|P22090|RS4Y1_HUMAN,tr|C9JEH7|C9JEH7_HUMAN" 3 1228.6444 1.17 80385 10610 3 1228.643643 410.5554 "40S ribosomal protein S4, X isoform OS=Homo sapiens OX=9606 GN=RPS4X PE=1 SV=2" 6.92 2086.8 - 1.09E+06 - - - -0.621 - 2.214 0.495 - 128.2 1 2 0 -0.0008 11 0 0 0 1.73E+07 1.48E+07 - - - 6.3164 1 221125_WJC_METTL3_EV_vs_WT_F06.10615.10615.2 1.73E-08 24-Nov R.NSEPAGLETPEAK.V "sp|P07814|SYEP_HUMAN,tr|V9GYZ6|V9GYZ6_HUMAN" 2 1341.6412 0.81 80389 10615 2 1341.636695 671.8279 Bifunctional glutamate\proline--tRNA ligase OS=Homo sapiens OX=9606 GN=EPRS1 PE=1 SV=5 4.25 2087.4 - 1.12E+06 - - - -3.3765 - 2.302 0.654 - 470.2 1 2 0 -0.0045 13 0 0 0 2.42E+07 2.99E+07 - - - 6.0099 1 221125_WJC_METTL3_EV_vs_WT_F06.10617.10617.3 3.15E-06 16/52 K.IVIGYQSHADTATK.S "sp|P06730|IF4E_HUMAN,tr|D6RBW1|D6RBW1_HUMAN" 2 1502.7729 1.46 80390 10617 3 1502.772033 501.9316 Eukaryotic translation initiation factor 4E OS=Homo sapiens OX=9606 GN=EIF4E PE=1 SV=2 6.74 2087.6 - 3.72E+06 - - - -0.5823 - 3.095 0.579 - 318.3 1 2 0 -0.0009 14 0 0 0 4.34E+08 2.96E+08 - - - 7.9975 0.9847 221125_WJC_METTL3_EV_vs_WT_F06.10618.10618.2 9.13 14-Aug P.DGIISK[136.11]PK[136.11].N sp|Q86U44|MTA70_HUMAN 1 872.5302 0.001 80391 10618 2 872.529789 437.2724 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 8.59 2087.7 - 2.58E+06 - - - -0.4917 - 1.892 0.382 - 194.7 1 1 0 -0.0004 8 0 0 0 0.00E+00 5.70E+07 - - - 3.7854 0.9986 221125_WJC_METTL3_EV_vs_WT_F06.10622.10622.2 2.05E-05 30-Nov R.VGLSGAPADAC[160.03]STAQK[136.11].A sp|Q8NFW8|NEUA_HUMAN 1 1539.7443 10.04 80395 10622 2 1539.739316 770.8794 N-acylneuraminate cytidylyltransferase OS=Homo sapiens OX=9606 GN=CMAS PE=1 SV=2 5.8 2088.2 - 369904 - - - -3.209 - 1.93 0.414 - 236.8 1 2 0 -0.0049 16 0 0 0 1.23E+08 1.23E+07 - - - 3.7138 0.9998 221125_WJC_METTL3_EV_vs_WT_F06.10624.10624.2 1.10E-05 26-Nov R.SLLEGEGSSGGGGR.G "sp|P13645|K1C10_HUMAN,tr|A0A1B0GVI3|A0A1B0GVI3_HUMAN" 2 1261.5899 6.7 80396 10624 2 1261.590641 631.8022 "Keratin, type I cytoskeletal 10 OS=Homo sapiens OX=9606 GN=KRT10 PE=1 SV=6" 4.53 2088.4 - 490346 - - - 0.6206 - 2.156 0.501 - 302.4 1 2 0 0.0008 14 0 0 0 3.10E+07 4.62E+06 - - - 4.669 0.9999 221125_WJC_METTL3_EV_vs_WT_F06.10626.10626.2 9.46E-05 22-Dec R.SSEDPNEDIVER.N "sp|P01591|IGJ_HUMAN,tr|D6RD17|D6RD17_HUMAN,tr|D6RHJ6|D6RHJ6_HUMAN,tr|C9JA05|C9JA05_HUMAN" 4 1388.6056 999 80397 10626 2 1388.606615 695.3101 Immunoglobulin J chain OS=Homo sapiens OX=9606 GN=JCHAIN PE=1 SV=4 3.83 2088.6 - 1.98E+06 - - - 0.7547 - 2.372 0.498 - 498.7 1 2 0 0.001 12 0 0 0 4.30E+07 0.00E+00 - - - 4.9915 0.9983 221125_WJC_METTL3_EV_vs_WT_F06.10627.10627.2 0.00603 20-Aug R.NAEPDEQDFEK[136.11].S "sp|Q14241|ELOA1_HUMAN,tr|A0A024RAC6|A0A024RAC6_HUMAN" 2 1328.5612 0.62 80398 10627 2 1328.556683 665.2879 Elongin-A OS=Homo sapiens OX=9606 GN=ELOA PE=1 SV=2 3.83 2088.7 - 5.24E+06 - - - -3.3924 - 1.388 0.504 - 176.3 1 2 0 -0.0045 11 0 0 0 2.09E+07 3.40E+07 - - - 3.6491 1 221125_WJC_METTL3_EV_vs_WT_F06.10629.10629.2 1.31E-07 16/26 R.NQSIIVSGESGAGK.T "sp|Q9Y4I1|MYO5A_HUMAN,sp|Q9ULV0|MYO5B_HUMAN,sp|Q9NQX4|MYO5C_HUMAN,tr|H0YM93|H0YM93_HUMAN,tr|H0YMK3|H0YMK3_HUMAN,tr|G3V394|G3V394_HUMAN,tr|F8WE88|F8WE88_HUMAN" 7 1345.6838 4.03 80400 10629 2 1345.683655 673.8492 Unconventional myosin-Va OS=Homo sapiens OX=9606 GN=MYO5A PE=1 SV=2 6 2088.9 - 1.16E+06 - - - -0.0765 - 3.033 0.625 - 928.2 1 2 0 -0.0001 14 0 0 0 2.17E+07 5.38E+06 - - - 6.4416 0.9991 221125_WJC_METTL3_EV_vs_WT_F06.10632.10632.2 1.1 14-Aug K.IQDWYDKK.G sp|P35527|K1C9_HUMAN 1 1094.5397 999 80401 10632 2 1094.540897 548.2771 "Keratin, type I cytoskeletal 9 OS=Homo sapiens OX=9606 GN=KRT9 PE=1 SV=3" 5.96 2089.3 - 4.37E+06 - - - 1.1302 - 1.626 0.315 - 180.2 1 2 0 0.0012 8 0 0 0 1.58E+08 0.00E+00 - - - 2.8333 0.9632 221125_WJC_METTL3_EV_vs_WT_F06.10633.10633.2 0.000544 16-Oct Y.PDGIISKPK[136.11].N sp|Q86U44|MTA70_HUMAN 1 961.5688 - 80402 10633 2 961.567957 481.7917 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 9.01 2089.4 - 1.16E+06 - - - -0.858 - 1.465 0.374 - 284.7 1 1 0 -0.0008 9 0 0 0 - - - - - 2.9078 0.9998 221125_WJC_METTL3_EV_vs_WT_F06.10634.10634.2 0.000147 18-Oct R.DHAISLSEPR.M "sp|Q9Y520|PRC2C_HUMAN,tr|E7EPN9|E7EPN9_HUMAN" 2 1123.5622 1.4 80403 10634 2 1123.562609 562.7884 Protein PRRC2C OS=Homo sapiens OX=9606 GN=PRRC2C PE=1 SV=4 5.32 2089.4 - 4.73E+06 - - - 0.3765 - 2.081 0.387 - 473.5 1 2 0 0.0004 10 0 0 0 1.03E+08 7.39E+07 - - - 3.9449 0.9989 221125_WJC_METTL3_EV_vs_WT_F06.10635.10635.2 0.0171 16-Aug R.DTQEVPLEK[136.11].A "sp|Q9Y5A9|YTHD2_HUMAN,sp|Q9BYJ9|YTHD1_HUMAN,sp|Q7Z739|YTHD3_HUMAN,tr|A0A087X0Q1|A0A087X0Q1_HUMAN,tr|A0A024R7W5|A0A024R7W5_HUMAN,tr|A0A087WY31|A0A087WY31_HUMAN" 6 1065.5434 1.54 80404 10635 2 1065.543967 533.779 YTH domain-containing family protein 2 OS=Homo sapiens OX=9606 GN=YTHDF2 PE=1 SV=2 4.14 2089.6 - 885659 - - - 0.5744 - 1.494 0.294 - 256.8 1 2 0 0.0006 9 0 0 0 2.75E+07 1.79E+07 - - - 2.3737 0.9999 221125_WJC_METTL3_EV_vs_WT_F06.10636.10636.2 5.42E-07 13/26 K.IVIGYQSHADTATK.S "sp|P06730|IF4E_HUMAN,tr|D6RBW1|D6RBW1_HUMAN" 2 1502.7729 1.45 80405 10636 2 1502.771311 752.3937 Eukaryotic translation initiation factor 4E OS=Homo sapiens OX=9606 GN=EIF4E PE=1 SV=2 6.74 2089.7 - 503054 - - - -1.0627 - 2.654 0.529 - 445.9 1 2 0 -0.0016 14 0 0 0 3.83E+07 2.63E+07 - - - 5.3971 0.9982 221125_WJC_METTL3_EV_vs_WT_F06.10637.10637.2 0.0245 16-Jul R.R[166.11]FDLQNPSR[166.11].M sp|Q92922|SMRC1_HUMAN 1 1151.595 5.34 80406 10637 2 1151.594954 576.8048 SWI\SNF complex subunit SMARCC1 OS=Homo sapiens OX=9606 GN=SMARCC1 PE=1 SV=3 9.6 2089.8 - 457559 - - - -0.079 - 1.479 0.228 - 99.1 1 2 0 -0.0001 9 0 0 0 8.64E+07 1.62E+07 - - - 1.8572 1 221125_WJC_METTL3_EV_vs_WT_F06.10642.10642.3 0.00118 14/40 K.EATDAIGHLDR.Q sp|Q12906|ILF3_HUMAN 1 1196.5786 1.15 80409 10642 3 1196.578036 399.8668 Interleukin enhancer-binding factor 3 OS=Homo sapiens OX=9606 GN=ILF3 PE=1 SV=3 4.54 2090.4 - 5.12E+06 - - - -0.4421 - 2.822 0.488 - 352.3 1 2 0 -0.0005 11 0 0 0 2.85E+08 2.48E+08 - - - 6.9278 1 221125_WJC_METTL3_EV_vs_WT_F06.10643.10643.3 0.00277 14/40 K.EATDAIGHLDR[166.11].Q sp|Q12906|ILF3_HUMAN 1 1206.5868 1.15 80410 10643 3 1206.585846 403.2029 Interleukin enhancer-binding factor 3 OS=Homo sapiens OX=9606 GN=ILF3 PE=1 SV=3 4.54 2090.5 - 4.64E+06 - - - -0.8197 - 2.775 0.417 - 400.3 1 2 0 -0.001 11 0 0 0 2.85E+08 2.48E+08 - - - 6.0884 0.9997 221125_WJC_METTL3_EV_vs_WT_F06.10645.10645.2 4.20E-05 20-Nov K.EATDAIGHLDR.Q sp|Q12906|ILF3_HUMAN 1 1196.5786 1.3 80412 10645 2 1196.580471 599.2966 Interleukin enhancer-binding factor 3 OS=Homo sapiens OX=9606 GN=ILF3 PE=1 SV=3 4.54 2090.6 - 1.53E+06 - - - 1.5929 - 2.029 0.463 - 419.5 1 2 0 0.0019 11 0 0 0 8.77E+07 6.74E+07 - - - 4.3742 1 221125_WJC_METTL3_EV_vs_WT_F06.10646.10646.3 7.02E-06 17/52 K.IEALQNHENESVYK.A "sp|P52292|IMA1_HUMAN,tr|A0A7I2YQE1|A0A7I2YQE1_HUMAN,tr|A0A7I2V487|A0A7I2V487_HUMAN,tr|A0A7I2V351|A0A7I2V351_HUMAN" 4 1672.8057 3.31 80413 10646 3 1672.805695 558.6092 Importin subunit alpha-1 OS=Homo sapiens OX=9606 GN=KPNA2 PE=1 SV=1 4.75 2090.8 - 1.48E+06 - - - 0.0185 - 2.924 0.468 - 330.5 1 2 0 0 14 0 0 0 1.91E+07 5.76E+06 - - - 6.6091 0.9999 221125_WJC_METTL3_EV_vs_WT_F06.10647.10647.3 3.04E-05 Dec-48 K.ASAHSIVEC[160.03]DPVR.K "sp|P52732|KIF11_HUMAN,tr|A0A7I2YQY4|A0A7I2YQY4_HUMAN,tr|A0A7I2V3V3|A0A7I2V3V3_HUMAN" 3 1439.6827 3.28 80414 10647 3 1439.684118 480.9015 Kinesin-like protein KIF11 OS=Homo sapiens OX=9606 GN=KIF11 PE=1 SV=2 5.32 2090.9 - 1.48E+06 - - - 0.9759 - 2.007 0.433 - 139.2 1 2 0 0.0014 13 0 0 0 8.13E+07 2.48E+07 - - - 5.2559 0.9588 221125_WJC_METTL3_EV_vs_WT_F06.10648.10648.3 0.000165 14/52 Q.TASAHLPAPAAVGR[166.11].R sp|Q8ND56|LS14A_HUMAN 1 1327.7236 1.06 80415 10648 3 1327.722449 443.5818 Protein LSM14 homolog A OS=Homo sapiens OX=9606 GN=LSM14A PE=1 SV=3 9.44 2090.9 - 1.47E+06 - - - -0.8692 - 2.713 0.25 - 403.8 1 1 0 -0.0012 14 0 0 0 4.75E+07 4.47E+07 - - - 3.9793 0.9989 221125_WJC_METTL3_EV_vs_WT_F06.10649.10649.2 1.93E-05 14/26 K.IVIGYQSHADTATK[136.11].S "sp|P06730|IF4E_HUMAN,tr|D6RBW1|D6RBW1_HUMAN" 2 1510.7871 1.45 80416 10649 2 1510.793526 756.4008 Eukaryotic translation initiation factor 4E OS=Homo sapiens OX=9606 GN=EIF4E PE=1 SV=2 6.74 2091.1 - 904336 - - - 4.2481 - 2.634 0.532 - 387.3 1 2 0 0.0064 14 0 0 0 3.83E+07 2.63E+07 - - - 5.3987 0.9999 221125_WJC_METTL3_EV_vs_WT_F06.10650.10650.2 7.26E-07 18-Oct R.HSDPESDFYR[166.11].G sp|O94864|ST65G_HUMAN 1 1261.5239 1.22 80417 10650 2 1261.525384 631.7692 STAGA complex 65 subunit gamma OS=Homo sapiens OX=9606 GN=SUPT7L PE=1 SV=1 4.54 2091.2 - 651417 - - - 1.1764 - 2.128 0.598 - 262.2 1 2 0 0.0015 10 0 0 0 1.42E+07 1.16E+07 - - - 5.5653 0.9946 221125_WJC_METTL3_EV_vs_WT_F06.10651.10651.3 0.000896 Dec-40 R.TIC[160.03]SSVDK[136.11]LDK[136.11].V "sp|P12081|HARS1_HUMAN,tr|A0A6Q8PF47|A0A6Q8PF47_HUMAN,tr|A0A6Q8PF07|A0A6Q8PF07_HUMAN,tr|B4E1C5|B4E1C5_HUMAN,tr|A0A6Q8PHA5|A0A6Q8PHA5_HUMAN,tr|E7ETE2|E7ETE2_HUMAN,tr|A0A6Q8PFF2|A0A6Q8PFF2_HUMAN,tr|A0A6Q8PHE3|A0A6Q8PHE3_HUMAN,tr|A0A6Q8PFG9|A0A6Q8PFG9_HUMAN,tr|B4DDD8|B4DDD8_HUMAN,tr|A0A6Q8PFN6|A0A6Q8PFN6_HUMAN" 11 1280.6617 10.77 80418 10651 3 1280.658736 427.8945 "Histidine--tRNA ligase, cytoplasmic OS=Homo sapiens OX=9606 GN=HARS1 PE=1 SV=2" 5.62 2091.3 - 591815 - - - -2.3168 - 1.998 0.295 - 195.8 1 2 1 -0.003 11 0 0 0 8.59E+07 7.97E+06 - - - 3.7944 1 221125_WJC_METTL3_EV_vs_WT_F06.10652.10652.2 1.33E-06 16/22 V.IGYQSHADTATK.S "sp|P06730|IF4E_HUMAN,tr|D6RBW1|D6RBW1_HUMAN" 2 1290.6204 2.09 80419 10652 2 1290.619589 646.3175 Eukaryotic translation initiation factor 4E OS=Homo sapiens OX=9606 GN=EIF4E PE=1 SV=2 6.74 2091.4 - 320103 - - - -0.6516 - 3.026 0.617 - 793.5 1 1 0 -0.0008 12 0 0 0 1.32E+07 6.30E+06 - - - 6.5112 0.9999 221125_WJC_METTL3_EV_vs_WT_F06.10655.10655.2 2.26E-08 15/20 K.EATDAIGHLDR[166.11].Q sp|Q12906|ILF3_HUMAN 1 1206.5868 1.32 80421 10655 2 1206.585558 604.3007 Interleukin enhancer-binding factor 3 OS=Homo sapiens OX=9606 GN=ILF3 PE=1 SV=3 4.54 2091.7 - 1.97E+06 - - - -1.0584 - 2.77 0.456 - 894.6 1 2 0 -0.0013 11 0 0 0 8.77E+07 6.66E+07 - - - 5.1648 0.9999 221125_WJC_METTL3_EV_vs_WT_F06.10656.10656.3 4.74E-05 13/44 R.ESLSTSSDLYKR.S sp|Q8TB72|PUM2_HUMAN 1 1384.6834 1.22 80422 10656 3 1384.68362 462.5684 Pumilio homolog 2 OS=Homo sapiens OX=9606 GN=PUM2 PE=1 SV=2 6.17 2091.8 - 4.19E+06 - - - 0.1415 - 3.196 0.345 - 404.9 1 2 0 0.0002 12 0 0 0 1.26E+08 1.03E+08 - - - 5.607 0.988 221125_WJC_METTL3_EV_vs_WT_F06.10658.10658.2 0.000121 12-Sep L.QDWYDKK.G sp|P35527|K1C9_HUMAN 1 981.4556 999 80424 10658 2 981.455522 491.7351 "Keratin, type I cytoskeletal 9 OS=Homo sapiens OX=9606 GN=KRT9 PE=1 SV=3" 5.96 2091.9 - 1.98E+06 - - - -0.0754 - 1.638 0.468 - 386.9 1 1 0 -0.0001 7 0 0 0 3.16E+07 0.00E+00 - - - 4.0612 0.9998 221125_WJC_METTL3_EV_vs_WT_F06.10659.10659.3 0.00316 Sep-44 R.IYDLNK[136.11]PEAEPK[136.11].E sp|Q9Y3F4|STRAP_HUMAN 1 1431.758 1.12 80425 10659 3 1431.759529 478.26 Serine-threonine kinase receptor-associated protein OS=Homo sapiens OX=9606 GN=STRAP PE=1 SV=1 4.68 2092.1 - 1.01E+06 - - - 1.0358 - 1.822 0.407 - 94 1 2 0 0.0015 12 0 0 0 2.22E+07 1.98E+07 - - - 4.7402 0.9999 221125_WJC_METTL3_EV_vs_WT_F06.10660.10660.3 0.00075 18/56 K.TPHPVLTPVAANQAK.Q "sp|P35658|NU214_HUMAN,tr|A0A0A0MSW3|A0A0A0MSW3_HUMAN,tr|A0A494C1F2|A0A494C1F2_HUMAN,tr|A0A494C104|A0A494C104_HUMAN,tr|H0Y837|H0Y837_HUMAN" 5 1542.8518 2.13 80426 10660 3 1542.851812 515.2912 Nuclear pore complex protein Nup214 OS=Homo sapiens OX=9606 GN=NUP214 PE=1 SV=2 8.44 2092.2 - 870771 - - - -0.0097 - 3.092 0.393 - 483.6 1 2 0 0 15 0 0 0 3.13E+08 1.47E+08 - - - 5.8671 0.9893 221125_WJC_METTL3_EV_vs_WT_F06.10662.10662.3 0.129 13/44 R.IYDLNKPEAEPK.E sp|Q9Y3F4|STRAP_HUMAN 1 1415.7296 0.9 80428 10662 3 1415.726801 472.9172 Serine-threonine kinase receptor-associated protein OS=Homo sapiens OX=9606 GN=STRAP PE=1 SV=1 4.68 2092.4 - 669113 - - - -2.0096 - 1.8 0.176 - 162.3 1 2 0 -0.0028 12 0 0 0 1.70E+07 1.90E+07 - - - 2.1307 1 221125_WJC_METTL3_EV_vs_WT_F06.10665.10665.3 0.194 14/44 R.ESLSTSSDLYK[136.11]R[166.11].S sp|Q8TB72|PUM2_HUMAN 1 1402.7059 1.54 80429 10665 3 1402.706336 468.5759 Pumilio homolog 2 OS=Homo sapiens OX=9606 GN=PUM2 PE=1 SV=2 6.17 2092.8 - 7.23E+06 - - - 0.3151 - 3.39 0.407 - 461.9 1 2 0 0.0004 12 0 0 0 1.61E+08 1.04E+08 - - - 6.4615 1 221125_WJC_METTL3_EV_vs_WT_F06.10666.10666.2 1.87E-07 18-Dec R.HSDPESDFYR.G sp|O94864|ST65G_HUMAN 1 1251.5156 1.22 80430 10666 2 1251.516729 626.7651 STAGA complex 65 subunit gamma OS=Homo sapiens OX=9606 GN=SUPT7L PE=1 SV=1 4.54 2093 - 1.45E+06 - - - 0.8781 - 2.342 0.655 - 420.3 1 2 0 0.0011 10 0 0 0 1.42E+07 1.16E+07 - - - 6.2539 0.9997 221125_WJC_METTL3_EV_vs_WT_F06.10667.10667.3 0.00151 15/56 K.TPHPVLTPVAANQAK[136.11].Q "sp|P35658|NU214_HUMAN,tr|A0A0A0MSW3|A0A0A0MSW3_HUMAN,tr|A0A494C1F2|A0A494C1F2_HUMAN,tr|A0A494C104|A0A494C104_HUMAN,tr|H0Y837|H0Y837_HUMAN" 5 1550.866 2.13 80431 10667 3 1550.863473 517.9626 Nuclear pore complex protein Nup214 OS=Homo sapiens OX=9606 GN=NUP214 PE=1 SV=2 8.44 2093.1 - 1.30E+06 - - - -1.6468 - 2.134 0.351 - 125.3 1 2 0 -0.0026 15 0 0 0 3.14E+08 1.47E+08 - - - 4.4305 0.9886 221125_WJC_METTL3_EV_vs_WT_F06.10668.10668.2 6.73E-05 22-Dec R.TIQGHLQSENFK[136.11].Q "sp|O15042|SR140_HUMAN,tr|E7ET15|E7ET15_HUMAN" 2 1408.719 3.19 80432 10668 2 1408.709873 705.3668 U2 snRNP-associated SURP motif-containing protein OS=Homo sapiens OX=9606 GN=U2SURP PE=1 SV=2 6.41 2093.2 - 958988 - - - -6.4988 - 1.835 0.457 - 259.5 1 2 0 -0.0092 12 0 0 0 1.22E+07 3.81E+06 - - - 4.0108 1 221125_WJC_METTL3_EV_vs_WT_F06.10670.10670.2 1.67E-07 16/28 K.AALSASEGEEVPQDK.A "sp|O95831|AIFM1_HUMAN,tr|A0A6Q8PFW2|A0A6Q8PFW2_HUMAN,tr|A0A6Q8PFA7|A0A6Q8PFA7_HUMAN,tr|A0A6Q8PFS4|A0A6Q8PFS4_HUMAN,tr|A0A7I2PK44|A0A7I2PK44_HUMAN,tr|A0A6Q8PF87|A0A6Q8PF87_HUMAN,tr|A0A6Q8PG15|A0A6Q8PG15_HUMAN,tr|A0A6Q8PFE1|A0A6Q8PFE1_HUMAN,tr|A0A6Q8PFQ8|A0A6Q8PFQ8_HUMAN,tr|A0A6Q8PFM5|A0A6Q8PFM5_HUMAN" 10 1529.7209 0.71 80434 10670 2 1529.724134 765.8677 "Apoptosis-inducing factor 1, mitochondrial OS=Homo sapiens OX=9606 GN=AIFM1 PE=1 SV=1" 4 2093.4 - 604179 - - - 2.0932 - 3.148 0.624 - 463 1 2 0 0.0032 15 0 0 0 2.42E+07 3.39E+07 - - - 6.4682 0.9788 221125_WJC_METTL3_EV_vs_WT_F06.10672.10672.2 1.21 20-Aug R.KVPPELNNISK.L "sp|Q5T8P6|RBM26_HUMAN,tr|A0A087X0H9|A0A087X0H9_HUMAN" 2 1237.703 1.36 80436 10672 2 1237.704477 619.8588 RNA-binding protein 26 OS=Homo sapiens OX=9606 GN=RBM26 PE=1 SV=3 8.59 2093.7 - 894591 - - - 1.1634 - 1.078 0.15 - 122.7 1 2 0 0.0014 11 0 0 0 5.82E+06 4.28E+06 - - - 0.3516 0.9937 221125_WJC_METTL3_EV_vs_WT_F06.10675.10675.3 0.000128 Dec-40 K.TGTITTFEHAH.N sp|P13639|EF2_HUMAN 1 1213.5728 - 80438 10675 3 1213.571653 405.5315 Elongation factor 2 OS=Homo sapiens OX=9606 GN=EEF2 PE=1 SV=4 5.92 2094 - 5.06E+06 - - - -0.9048 - 2.002 0.465 - 230.2 1 1 0 -0.0011 11 0 0 0 - - - - - 5.6959 0.9983 221125_WJC_METTL3_EV_vs_WT_F06.10677.10677.2 0.00109 16-Nov K.YKDDPVDLR.L "sp|Q9Y2W1|TR150_HUMAN,tr|A0A3B3ITZ9|A0A3B3ITZ9_HUMAN" 2 1119.556 2.62 80440 10677 2 1119.556906 560.7853 Thyroid hormone receptor-associated protein 3 OS=Homo sapiens OX=9606 GN=THRAP3 PE=1 SV=2 4.43 2094.2 - 1.47E+07 - - - 0.7753 - 2.135 0.486 - 389.9 1 2 1 0.0009 9 0 0 0 4.81E+08 1.84E+08 - - - 4.8246 0.9999 221125_WJC_METTL3_EV_vs_WT_F06.10678.10678.3 0.00504 14/52 K.ILIEESQDAPDHSK.F "sp|Q96AV8|E2F7_HUMAN,tr|H0YHW2|H0YHW2_HUMAN,tr|F8VSE7|F8VSE7_HUMAN,tr|H0YIF4|H0YIF4_HUMAN" 4 1580.7682 1.36 80441 10678 3 1580.769493 527.93 Transcription factor E2F7 OS=Homo sapiens OX=9606 GN=E2F7 PE=1 SV=3 4.31 2094.3 - 1.19E+06 - - - 0.8078 - 2.307 0.418 - 206.2 1 2 0 0.0013 14 0 0 0 1.46E+07 1.07E+07 - - - 5.4215 1 221125_WJC_METTL3_EV_vs_WT_F06.10683.10683.2 7.23E-06 19/28 K.AALSASEGEEVPQDK[136.11].A "sp|O95831|AIFM1_HUMAN,tr|A0A6Q8PFW2|A0A6Q8PFW2_HUMAN,tr|A0A6Q8PFA7|A0A6Q8PFA7_HUMAN,tr|A0A6Q8PFS4|A0A6Q8PFS4_HUMAN,tr|A0A7I2PK44|A0A7I2PK44_HUMAN,tr|A0A6Q8PF87|A0A6Q8PF87_HUMAN,tr|A0A6Q8PG15|A0A6Q8PG15_HUMAN,tr|A0A6Q8PFE1|A0A6Q8PFE1_HUMAN,tr|A0A6Q8PFQ8|A0A6Q8PFQ8_HUMAN,tr|A0A6Q8PFM5|A0A6Q8PFM5_HUMAN" 10 1537.7351 0.72 80444 10683 2 1537.735735 769.8748 "Apoptosis-inducing factor 1, mitochondrial OS=Homo sapiens OX=9606 GN=AIFM1 PE=1 SV=1" 4 2094.9 - 1.68E+06 - - - 0.3921 - 3.267 0.577 - 740 1 2 0 0.0006 15 0 0 0 2.48E+07 3.42E+07 - - - 6.2131 0.9998 221125_WJC_METTL3_EV_vs_WT_F06.10687.10687.2 0.00196 22-Nov K.GEDEEENNLEVR[166.11].E "sp|P04843|RPN1_HUMAN,tr|F8WF32|F8WF32_HUMAN" 2 1441.6197 2.65 80448 10687 2 1441.621894 721.8171 Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit 1 OS=Homo sapiens OX=9606 GN=RPN1 PE=1 SV=1 3.83 2095.3 - 1.03E+06 - - - 1.5559 - 2.55 0.487 - 561.8 1 2 0 0.0022 12 0 0 0 4.40E+07 1.66E+07 - - - 5.1003 0.9999 221125_WJC_METTL3_EV_vs_WT_F06.10691.10691.2 3.06E-09 13/28 K.TPHPVLTPVAANQAK.Q "sp|P35658|NU214_HUMAN,tr|A0A0A0MSW3|A0A0A0MSW3_HUMAN,tr|A0A494C1F2|A0A494C1F2_HUMAN,tr|A0A494C104|A0A494C104_HUMAN,tr|H0Y837|H0Y837_HUMAN" 5 1542.8518 2.62 80452 10691 2 1542.853982 772.4332 Nuclear pore complex protein Nup214 OS=Homo sapiens OX=9606 GN=NUP214 PE=1 SV=2 8.44 2095.8 - 379477 - - - 1.3968 - 2.541 0.593 - 433.9 1 2 0 0.0022 15 0 0 0 2.30E+07 8.78E+06 - - - 5.713 0.9243 221125_WJC_METTL3_EV_vs_WT_F06.10693.10693.2 0.00241 20-Oct K.TGTITTFEHAH.N sp|P13639|EF2_HUMAN 1 1213.5728 - 80453 10693 2 1213.57558 607.7937 Elongation factor 2 OS=Homo sapiens OX=9606 GN=EEF2 PE=1 SV=4 5.92 2096.1 - 540286 - - - 2.3311 - 1.704 0.352 - 207 1 1 0 0.0028 11 0 0 0 - - - - - 3.0818 0.9994 221125_WJC_METTL3_EV_vs_WT_F06.10694.10694.2 0.595 18-Nov R.HAYLQQTFSK.L sp|Q86X52|CHSS1_HUMAN 1 1221.6142 1.71 80454 10694 2 1221.61273 611.8144 Chondroitin sulfate synthase 1 OS=Homo sapiens OX=9606 GN=CHSY1 PE=1 SV=3 8.6 2096.2 - 553602 - - - -1.2213 - 1.998 0.283 - 323.4 1 2 0 -0.0015 10 0 0 0 7.77E+06 4.54E+06 - - - 3.0628 0.9999 221125_WJC_METTL3_EV_vs_WT_F06.10697.10697.2 1.22E-05 22-Nov R.ESLSTSSDLYK[136.11]R[166.11].S sp|Q8TB72|PUM2_HUMAN 1 1402.7059 1.12 80457 10697 2 1402.705955 702.3602 Pumilio homolog 2 OS=Homo sapiens OX=9606 GN=PUM2 PE=1 SV=2 6.17 2096.5 - 1.50E+06 - - - 0.0435 - 2.103 0.538 - 562.3 1 2 0 0.0001 12 0 0 0 1.41E+07 1.25E+07 - - - 4.9706 0.9999 221125_WJC_METTL3_EV_vs_WT_F06.10698.10698.3 0.00015 Dec-48 R.ELAGHTGYLSC[160.03]C[160.03]R.F "sp|P62873|GBB1_HUMAN,tr|B3KVK2|B3KVK2_HUMAN,tr|F6X3N5|F6X3N5_HUMAN,tr|F6UT28|F6UT28_HUMAN" 4 1522.6657 1.08 80458 10698 3 1522.662836 508.5625 Guanine nucleotide-binding protein G(I)\G(S)\G(T) subunit beta-1 OS=Homo sapiens OX=9606 GN=GNB1 PE=1 SV=3 6.82 2096.7 - 977728 - - - -1.8697 - 1.954 0.461 - 98.4 1 2 0 -0.0028 13 0 0 0 1.62E+07 1.50E+07 - - - 5.4951 0.999 221125_WJC_METTL3_EV_vs_WT_F06.10700.10700.2 0.461 20-Sep R.AGELTEDEVER[166.11].V sp|P62269|RS18_HUMAN 1 1256.576 1.37 80460 10700 2 1256.573449 629.2953 40S ribosomal protein S18 OS=Homo sapiens OX=9606 GN=RPS18 PE=1 SV=3 3.91 2096.9 - 556417 - - - -2.0261 - 1.866 0.318 - 337.8 1 2 0 -0.0025 11 0 0 0 6.65E+06 4.87E+06 - - - 3.0765 0.9904 221125_WJC_METTL3_EV_vs_WT_F06.10701.10701.2 5.00E-05 18-Nov E.ATDAIGHLDR[166.11].Q sp|Q12906|ILF3_HUMAN 1 1077.5442 1.41 80461 10701 2 1077.545246 539.7794 Interleukin enhancer-binding factor 3 OS=Homo sapiens OX=9606 GN=ILF3 PE=1 SV=3 5.21 2097 - 496660 - - - 0.9317 - 2.257 0.471 - 570.9 1 1 0 0.001 10 0 0 0 8.84E+06 6.27E+06 - - - 4.7917 0.9971 221125_WJC_METTL3_EV_vs_WT_F06.10704.10704.3 0.000848 Oct-32 K.YK[136.11]DDPVDLR[166.11].L "sp|Q9Y2W1|TR150_HUMAN,tr|A0A3B3ITZ9|A0A3B3ITZ9_HUMAN" 2 1137.5785 0.001 80462 10704 3 1137.578335 380.2001 Thyroid hormone receptor-associated protein 3 OS=Homo sapiens OX=9606 GN=THRAP3 PE=1 SV=2 4.43 2097.4 - 4.22E+07 - - - -0.1521 - 1.715 0.311 - 162.6 1 2 1 -0.0002 9 0 0 0 0.00E+00 4.06E+08 - - - 3.633 1 221125_WJC_METTL3_EV_vs_WT_F06.10705.10705.3 3.25E-07 15/52 K.IVIGYQSHADTATK[136.11].S "sp|P06730|IF4E_HUMAN,tr|D6RBW1|D6RBW1_HUMAN" 2 1510.7871 1.45 80463 10705 3 1510.786625 504.603 Eukaryotic translation initiation factor 4E OS=Homo sapiens OX=9606 GN=EIF4E PE=1 SV=2 6.74 2097.5 - 1.48E+07 - - - -0.3197 - 2.994 0.59 - 253.8 1 2 0 -0.0005 14 0 0 0 4.34E+08 2.99E+08 - - - 8.0321 0.9986 221125_WJC_METTL3_EV_vs_WT_F06.10706.10706.2 6.15E-06 16-Oct K.YK[136.11]DDPVDLR[166.11].L "sp|Q9Y2W1|TR150_HUMAN,tr|A0A3B3ITZ9|A0A3B3ITZ9_HUMAN" 2 1137.5785 2.6 80464 10706 2 1137.578887 569.7965 Thyroid hormone receptor-associated protein 3 OS=Homo sapiens OX=9606 GN=THRAP3 PE=1 SV=2 4.43 2097.5 - 1.81E+07 - - - 0.3332 - 1.947 0.523 - 323.6 1 2 1 0.0004 9 0 0 0 4.81E+08 1.85E+08 - - - 4.8314 1 221125_WJC_METTL3_EV_vs_WT_F06.10709.10709.3 4.90E-07 17/60 R.YGEAGEGPGWGGAHPR[166.11].L "sp|P26640|SYVC_HUMAN,tr|A0A0G2JJT9|A0A0G2JJT9_HUMAN,tr|A2ABF4|A2ABF4_HUMAN,tr|A0A140T954|A0A140T954_HUMAN" 4 1606.7152 0.59 80467 10709 3 1606.712889 536.579 Valine--tRNA ligase OS=Homo sapiens OX=9606 GN=VARS1 PE=1 SV=4 5.4 2097.8 - 2.10E+06 - - - -1.4527 - 3.164 0.619 - 273.5 1 2 0 -0.0023 16 0 0 0 1.41E+07 2.38E+07 - - - 8.396 0.9438 221125_WJC_METTL3_EV_vs_WT_F06.10712.10712.2 0.131 16-Aug R.MDYEDDRLR.D "sp|P43243|MATR3_HUMAN,tr|A8MXP9|A8MXP9_HUMAN,tr|D6R991|D6R991_HUMAN,tr|A0A0R4J2E8|A0A0R4J2E8_HUMAN,tr|D6REM6|D6REM6_HUMAN" 5 1211.5241 1.38 80470 10712 2 1211.52529 606.7693 Matrin-3 OS=Homo sapiens OX=9606 GN=MATR3 PE=1 SV=2 4.23 2098.1 - 899181 - - - 0.9938 - 1.065 0.276 - 172.7 1 2 1 0.0012 9 0 0 0 1.39E+07 1.01E+07 - - - 1.2613 1 221125_WJC_METTL3_EV_vs_WT_F06.10714.10714.2 1.56E-11 17/28 K.TPHPVLTPVAANQAK[136.11].Q "sp|P35658|NU214_HUMAN,tr|A0A0A0MSW3|A0A0A0MSW3_HUMAN,tr|A0A494C1F2|A0A494C1F2_HUMAN,tr|A0A494C104|A0A494C104_HUMAN,tr|H0Y837|H0Y837_HUMAN" 5 1550.866 2.55 80472 10714 2 1550.862795 776.4403 Nuclear pore complex protein Nup214 OS=Homo sapiens OX=9606 GN=NUP214 PE=1 SV=2 8.44 2098.4 - 493869 - - - -2.084 - 2.792 0.665 - 731.7 1 2 0 -0.0032 15 0 0 0 2.24E+07 8.78E+06 - - - 6.476 0.9993 221125_WJC_METTL3_EV_vs_WT_F06.10719.10719.3 3.66E-05 Sep-32 R.MDYEDDRLR.D "sp|P43243|MATR3_HUMAN,tr|A8MXP9|A8MXP9_HUMAN,tr|D6R991|D6R991_HUMAN,tr|A0A0R4J2E8|A0A0R4J2E8_HUMAN,tr|D6REM6|D6REM6_HUMAN" 5 1211.5241 1.14 80475 10719 3 1211.522746 404.8486 Matrin-3 OS=Homo sapiens OX=9606 GN=MATR3 PE=1 SV=2 4.23 2099 - 9.96E+06 - - - -1.106 - 1.74 0.421 - 230.8 1 2 1 -0.0013 9 0 0 0 8.00E+07 7.02E+07 - - - 4.9027 0.9994 221125_WJC_METTL3_EV_vs_WT_F06.10722.10722.3 0.0022 Oct-48 R.ELAGHTGYLSC[160.03]C[160.03]R[166.11].F "sp|P62873|GBB1_HUMAN,tr|B3KVK2|B3KVK2_HUMAN,tr|F6X3N5|F6X3N5_HUMAN,tr|F6UT28|F6UT28_HUMAN" 4 1532.674 1.08 80478 10722 3 1532.673118 511.8986 Guanine nucleotide-binding protein G(I)\G(S)\G(T) subunit beta-1 OS=Homo sapiens OX=9606 GN=GNB1 PE=1 SV=3 6.82 2099.2 - 1.58E+06 - - - -0.5448 - 1.585 0.348 - 64.8 1 2 0 -0.0008 13 0 0 0 1.62E+07 1.50E+07 - - - 3.6684 0.9421 221125_WJC_METTL3_EV_vs_WT_F06.10727.10727.2 0.0289 22-Sep R.NGPGFHNDIDSN.S sp|Q96I24|FUBP3_HUMAN 1 1285.5323 - 80483 10727 2 1285.534711 643.7734 Far upstream element-binding protein 3 OS=Homo sapiens OX=9606 GN=FUBP3 PE=1 SV=2 4.2 2099.8 - 454435 - - - 1.842 - 1.384 0.427 - 204.5 1 1 0 0.0024 12 0 0 0 - - - - - 3.0492 0.9999 221125_WJC_METTL3_EV_vs_WT_F06.10732.10732.3 1.75E-05 14/44 R.RDSLTGSSDLYK.R "sp|Q14671|PUM1_HUMAN,tr|Q5T1Z8|Q5T1Z8_HUMAN,tr|H0YDK8|H0YDK8_HUMAN,tr|Q5T1Z4|Q5T1Z4_HUMAN,tr|E9PR38|E9PR38_HUMAN" 5 1340.6572 1.67 80486 10732 3 1340.657313 447.893 Pumilio homolog 1 OS=Homo sapiens OX=9606 GN=PUM1 PE=1 SV=3 5.96 2100.4 - 1.21E+06 - - - 0.0776 - 2.558 0.349 - 329.7 1 2 0 0.0001 12 0 0 0 1.86E+07 1.12E+07 - - - 5.0344 1 221125_WJC_METTL3_EV_vs_WT_F06.10735.10735.3 2.51E-09 16/60 R.YGEAGEGPGWGGAHPR.L "sp|P26640|SYVC_HUMAN,tr|A0A0G2JJT9|A0A0G2JJT9_HUMAN,tr|A2ABF4|A2ABF4_HUMAN,tr|A0A140T954|A0A140T954_HUMAN" 4 1596.707 0.59 80489 10735 3 1596.70603 533.2429 Valine--tRNA ligase OS=Homo sapiens OX=9606 GN=VARS1 PE=1 SV=4 5.4 2100.6 - 1.78E+06 - - - -0.5781 - 3.178 0.606 - 247.5 1 2 0 -0.0009 16 0 0 0 1.41E+07 2.38E+07 - - - 8.2628 0.9972 221125_WJC_METTL3_EV_vs_WT_F06.10736.10736.3 5.06E-07 15/52 K.ITESVAETAQTIKK.S sp|Q96A49|SYAP1_HUMAN 1 1517.8301 1.36 80490 10736 3 1517.821679 506.9506 Synapse-associated protein 1 OS=Homo sapiens OX=9606 GN=SYAP1 PE=1 SV=1 6.14 2100.7 - 1.39E+06 - - - -5.5401 - 2.778 0.34 - 418.3 1 2 0 -0.0084 14 0 0 0 1.90E+09 1.39E+09 - - - 5.0436 0.9998 221125_WJC_METTL3_EV_vs_WT_F06.10737.10737.2 0.000207 20-Nov R.NFSDNQLQEGK.N "sp|P37802|TAGL2_HUMAN,tr|X6RJP6|X6RJP6_HUMAN" 2 1278.584 1.76 80491 10737 2 1278.585054 640.2993 Transgelin-2 OS=Homo sapiens OX=9606 GN=TAGLN2 PE=1 SV=3 4.37 2100.8 - 1.31E+06 - - - 0.7899 - 2.108 0.444 - 292.8 1 2 0 0.001 11 0 0 0 4.54E+07 2.58E+07 - - - 4.3375 1 221125_WJC_METTL3_EV_vs_WT_F06.10738.10738.3 4.65E-05 16/52 K.ITESVAETAQTIK[136.11]K[136.11].S sp|Q96A49|SYAP1_HUMAN 1 1533.8585 1.36 80492 10738 3 1533.860729 512.2934 Synapse-associated protein 1 OS=Homo sapiens OX=9606 GN=SYAP1 PE=1 SV=1 6.14 2100.9 - 1.26E+06 - - - 1.461 - 2.844 0.46 - 290.2 1 2 0 0.0022 14 0 0 0 1.90E+09 1.39E+09 - - - 6.4456 0.9999 221125_WJC_METTL3_EV_vs_WT_F06.10739.10739.2 9.13E-05 13/26 R.VANVSAAEDSVSQR[166.11].A "sp|Q9NY93|DDX56_HUMAN,tr|F8WDT8|F8WDT8_HUMAN,tr|G3V0G3|G3V0G3_HUMAN,tr|H7C3E9|H7C3E9_HUMAN" 4 1441.7037 0.79 80493 10739 2 1441.702057 721.8591 Probable ATP-dependent RNA helicase DDX56 OS=Homo sapiens OX=9606 GN=DDX56 PE=1 SV=1 4.37 2101 - 1.14E+06 - - - -1.1091 - 2.557 0.505 - 538.6 1 2 0 -0.0016 14 0 0 0 1.09E+07 1.39E+07 - - - 5.1264 0.893 221125_WJC_METTL3_EV_vs_WT_F06.10740.10740.2 0.222 16-Jul R.MDYEDDR[166.11]LR[166.11].D "sp|P43243|MATR3_HUMAN,tr|A8MXP9|A8MXP9_HUMAN,tr|D6R991|D6R991_HUMAN,tr|A0A0R4J2E8|A0A0R4J2E8_HUMAN,tr|D6REM6|D6REM6_HUMAN" 5 1231.5406 1.38 80494 10740 2 1231.540381 616.7776 Matrin-3 OS=Homo sapiens OX=9606 GN=MATR3 PE=1 SV=2 4.23 2101.2 - 1.10E+06 - - - -0.1989 - 0.948 0.229 - 140.4 1 2 1 -0.0002 9 0 0 0 1.39E+07 1.01E+07 - - - 0.5778 0.9999 221125_WJC_METTL3_EV_vs_WT_F06.10741.10741.2 6.20E-07 14/20 R.NFSDNQLQEGK[136.11].N "sp|P37802|TAGL2_HUMAN,tr|X6RJP6|X6RJP6_HUMAN" 2 1286.5982 1.65 80495 10741 2 1286.599161 644.3064 Transgelin-2 OS=Homo sapiens OX=9606 GN=TAGLN2 PE=1 SV=3 4.37 2101.3 - 974814 - - - 0.7127 - 2.377 0.584 - 542.7 1 2 0 0.0009 11 0 0 0 4.25E+07 2.58E+07 - - - 5.6964 0.9999 221125_WJC_METTL3_EV_vs_WT_F06.10746.10746.3 2.10E-06 Sep-32 R.MDYEDDR[166.11]LR[166.11].D "sp|P43243|MATR3_HUMAN,tr|A8MXP9|A8MXP9_HUMAN,tr|D6R991|D6R991_HUMAN,tr|A0A0R4J2E8|A0A0R4J2E8_HUMAN,tr|D6REM6|D6REM6_HUMAN" 5 1231.5406 1.14 80499 10746 3 1231.540103 411.5208 Matrin-3 OS=Homo sapiens OX=9606 GN=MATR3 PE=1 SV=2 4.23 2101.8 - 5.52E+06 - - - -0.4247 - 1.859 0.57 - 217.6 1 2 1 -0.0005 9 0 0 0 8.00E+07 7.01E+07 - - - 6.7635 1 221125_WJC_METTL3_EV_vs_WT_F06.10747.10747.3 7.79E-09 13/44 R.RLDQC[160.03]PESPLQR.C sp|Q5T749|KPRP_HUMAN 1 1497.7358 94.45 80500 10747 3 1497.736831 500.2525 Keratinocyte proline-rich protein OS=Homo sapiens OX=9606 GN=KPRP PE=1 SV=1 6.06 2101.9 - 5.64E+06 - - - 0.681 - 2.994 0.558 - 273.7 1 2 0 0.001 12 0 0 0 3.48E+08 3.68E+06 - - - 7.8005 0.9995 221125_WJC_METTL3_EV_vs_WT_F06.10750.10750.2 0.014 13/22 R.RDSLTGSSDLYK.R "sp|Q14671|PUM1_HUMAN,tr|Q5T1Z8|Q5T1Z8_HUMAN,tr|H0YDK8|H0YDK8_HUMAN,tr|Q5T1Z4|Q5T1Z4_HUMAN,tr|E9PR38|E9PR38_HUMAN" 5 1340.6572 2.86 80503 10750 2 1340.659294 671.3359 Pumilio homolog 1 OS=Homo sapiens OX=9606 GN=PUM1 PE=1 SV=3 5.96 2102.2 - 1.28E+06 - - - 1.5552 - 2.191 0.345 - 448.8 1 2 0 0.0021 12 0 0 0 9.17E+06 3.21E+06 - - - 3.6523 0.9969 221125_WJC_METTL3_EV_vs_WT_F06.10752.10752.2 1.60E-06 15/22 K.LQMEQQQQLQQR.Q sp|Q9NS69|TOM22_HUMAN 1 1556.7729 1.19 80505 10752 2 1556.768329 779.3937 Mitochondrial import receptor subunit TOM22 homolog OS=Homo sapiens OX=9606 GN=TOMM22 PE=1 SV=3 6 2102.4 - 766349 - - - -2.9516 - 2.606 0.151 - 943.1 1 2 0 -0.0046 12 0 0 0 1.40E+07 1.18E+07 - - - 2.675 0.9999 221125_WJC_METTL3_EV_vs_WT_F06.10753.10753.2 2.81E-05 15/22 K.LQMEQQQQLQQR[166.11].Q sp|Q9NS69|TOM22_HUMAN 1 1566.7812 1.19 80506 10753 2 1566.781277 784.3979 Mitochondrial import receptor subunit TOM22 homolog OS=Homo sapiens OX=9606 GN=TOMM22 PE=1 SV=3 6 2102.5 - 686008 - - - 0.053 - 2.977 0.514 - 988.8 1 2 0 0.0001 12 0 0 0 1.40E+07 1.18E+07 - - - 5.7078 0.9998 221125_WJC_METTL3_EV_vs_WT_F06.10754.10754.2 2.71E-06 26-Nov K.GDATVSYEDPPTAK.A "sp|Q01844|EWS_HUMAN,tr|B0QYK0|B0QYK0_HUMAN,tr|H7BY36|H7BY36_HUMAN,tr|A0A0D9SFL3|A0A0D9SFL3_HUMAN,tr|C9JGE3|C9JGE3_HUMAN" 5 1449.6624 0.71 80507 10754 2 1449.660993 725.8385 RNA-binding protein EWS OS=Homo sapiens OX=9606 GN=EWSR1 PE=1 SV=1 4.03 2102.6 - 672911 - - - -0.9388 - 1.998 0.493 - 197.4 1 2 0 -0.0014 14 0 0 0 1.72E+09 2.41E+09 - - - 4.4188 0.9771 221125_WJC_METTL3_EV_vs_WT_F06.10757.10757.2 0.000134 26-Nov A.GGPGPGGFGAQGPK[136.11].G "sp|P0DMV8|HS71A_HUMAN,sp|P0DMV9|HS71B_HUMAN,tr|V9GZ37|V9GZ37_HUMAN,tr|A0A0G2JIW1|A0A0G2JIW1_HUMAN" 4 1190.5924 0.26 80510 10757 2 1190.594889 596.3035 Heat shock 70 kDa protein 1A OS=Homo sapiens OX=9606 GN=HSPA1A PE=1 SV=1 8.75 2103 - 465771 - - - 2.1149 - 2.141 0.472 - 302.2 1 1 0 0.0025 14 0 0 0 5.84E+06 2.23E+07 - - - 4.4368 1 221125_WJC_METTL3_EV_vs_WT_F06.10758.10758.2 7.13E-10 16/26 K.ITESVAETAQTIKK.S sp|Q96A49|SYAP1_HUMAN 1 1517.8301 1.39 80511 10758 2 1517.83048 759.9223 Synapse-associated protein 1 OS=Homo sapiens OX=9606 GN=SYAP1 PE=1 SV=1 6.14 2103.1 - 453593 - - - 0.2583 - 3.262 0.66 - 900.6 1 2 0 0.0004 14 0 0 0 1.57E+08 1.13E+08 - - - 6.8827 0.9998 221125_WJC_METTL3_EV_vs_WT_F06.10759.10759.2 0.000307 20-Dec R.QQSEISAAVER.A "sp|Q9Y520|PRC2C_HUMAN,tr|A0A0A0MS30|A0A0A0MS30_HUMAN,tr|E7EPN9|E7EPN9_HUMAN" 3 1216.6048 1.42 80512 10759 2 1216.603761 609.3097 Protein PRRC2C OS=Homo sapiens OX=9606 GN=PRRC2C PE=1 SV=4 4.53 2103.3 - 257262 - - - -0.8376 - 2.141 0.434 - 612.2 1 2 0 -0.001 11 0 0 0 7.92E+06 5.56E+06 - - - 4.3056 0.9713 221125_WJC_METTL3_EV_vs_WT_F06.10763.10763.3 0.00305 Nov-36 R.GANLK[136.11]DYYSR[166.11].K sp|Q08211|DHX9_HUMAN 1 1203.6003 0.54 80514 10763 3 1203.596794 402.2074 ATP-dependent RNA helicase A OS=Homo sapiens OX=9606 GN=DHX9 PE=1 SV=4 8.5 2103.8 - 3.07E+06 - - - -2.9179 - 1.628 0.263 - 194.6 1 2 1 -0.0035 10 0 0 0 1.14E+07 2.10E+07 - - - 2.8945 1 221125_WJC_METTL3_EV_vs_WT_F06.10765.10765.2 2.68E-08 16/26 K.ITESVAETAQTIK[136.11]K[136.11].S sp|Q96A49|SYAP1_HUMAN 1 1533.8585 1.39 80516 10765 2 1533.859073 767.9365 Synapse-associated protein 1 OS=Homo sapiens OX=9606 GN=SYAP1 PE=1 SV=1 6.14 2103.9 - 2.94E+06 - - - 0.3814 - 3.282 0.622 - 878.2 1 2 0 0.0006 14 0 0 0 1.57E+08 1.13E+08 - - - 6.6173 0.9999 221125_WJC_METTL3_EV_vs_WT_F06.10768.10768.3 9.38E-05 Nov-44 K.LQMEQQQQLQQR.Q sp|Q9NS69|TOM22_HUMAN 1 1556.7729 1.62 80519 10768 3 1556.772589 519.9316 Mitochondrial import receptor subunit TOM22 homolog OS=Homo sapiens OX=9606 GN=TOMM22 PE=1 SV=3 6 2104.1 - 1.79E+06 - - - -0.2152 - 2.056 0.445 - 264 1 2 0 -0.0003 12 0 0 0 1.37E+07 8.45E+06 - - - 5.4991 0.9995 221125_WJC_METTL3_EV_vs_WT_F06.10769.10769.2 0.000233 22-Nov K.VYVGNLGNNGNK.T "sp|P84103|SRSF3_HUMAN,tr|A0A087X2D0|A0A087X2D0_HUMAN" 2 1247.6258 1.38 80520 10769 2 1247.628032 624.8202 Serine\arginine-rich splicing factor 3 OS=Homo sapiens OX=9606 GN=SRSF3 PE=1 SV=1 8.56 2104.2 - 1.48E+06 - - - 1.7497 - 1.957 0.42 - 310 1 2 0 0.0022 12 0 0 0 1.29E+07 9.31E+06 - - - 3.909 0.9999 221125_WJC_METTL3_EV_vs_WT_F06.10770.10770.2 0.000133 13/22 R.RLDQC[160.03]PESPLQR.C sp|Q5T749|KPRP_HUMAN 1 1497.7358 999 80521 10770 2 1497.737677 749.8752 Keratinocyte proline-rich protein OS=Homo sapiens OX=9606 GN=KPRP PE=1 SV=1 6.06 2104.3 - 1.22E+06 - - - 1.2459 - 2.831 0.529 - 181.2 1 2 0 0.0019 12 0 0 0 5.39E+07 0.00E+00 - - - 5.6857 0.9997 221125_WJC_METTL3_EV_vs_WT_F06.10771.10771.3 0.0138 Dec-44 K.LQMEQQQQLQQR[166.11].Q sp|Q9NS69|TOM22_HUMAN 1 1566.7812 1.66 80522 10771 3 1566.78149 523.2677 Mitochondrial import receptor subunit TOM22 homolog OS=Homo sapiens OX=9606 GN=TOMM22 PE=1 SV=3 6 2104.4 - 1.20E+06 - - - 0.1889 - 2.294 0.298 - 299.6 1 2 0 0.0003 12 0 0 0 1.33E+07 7.98E+06 - - - 4.1638 1 221125_WJC_METTL3_EV_vs_WT_F06.10773.10773.2 1.46E-07 16/24 L.TESVAETAQTIKK.S sp|Q96A49|SYAP1_HUMAN 1 1404.746 1.19 80524 10773 2 1404.747925 703.3803 Synapse-associated protein 1 OS=Homo sapiens OX=9606 GN=SYAP1 PE=1 SV=1 5.81 2104.7 - 718010 - - - 1.3533 - 3.011 0.555 - 1065 1 1 0 0.0019 13 0 0 0 4.14E+07 3.47E+07 - - - 5.9686 1 221125_WJC_METTL3_EV_vs_WT_F06.10775.10775.2 8.09E-09 16/28 F.DSGFGGGAGVETGGK.L "sp|Q86V81|THOC4_HUMAN,tr|E9PB61|E9PB61_HUMAN" 2 1294.579 0.26 80526 10775 2 1294.578313 648.2968 THO complex subunit 4 OS=Homo sapiens OX=9606 GN=ALYREF PE=1 SV=3 4.37 2104.9 - 665759 - - - -0.499 - 2.767 0.683 - 766.7 1 1 0 -0.0006 15 0 0 0 6.17E+07 2.34E+08 - - - 6.5877 0.9943 221125_WJC_METTL3_EV_vs_WT_F06.10776.10776.2 6.25E-05 14/24 L.TESVAETAQTIK[136.11]K[136.11].S sp|Q96A49|SYAP1_HUMAN 1 1420.7744 1.19 80527 10776 2 1420.774834 711.3945 Synapse-associated protein 1 OS=Homo sapiens OX=9606 GN=SYAP1 PE=1 SV=1 5.81 2105.1 - 654301 - - - 0.2886 - 2.842 0.498 - 719.7 1 1 0 0.0004 13 0 0 0 4.12E+07 3.47E+07 - - - 5.3999 0.9997 221125_WJC_METTL3_EV_vs_WT_F06.10778.10778.2 0.000215 20-Nov R.QQSEISAAVER[166.11].A "sp|Q9Y520|PRC2C_HUMAN,tr|A0A0A0MS30|A0A0A0MS30_HUMAN,tr|E7EPN9|E7EPN9_HUMAN" 3 1226.613 1.23 80529 10778 2 1226.61219 614.3138 Protein PRRC2C OS=Homo sapiens OX=9606 GN=PRRC2C PE=1 SV=4 4.53 2105.3 - 627428 - - - -0.7011 - 2.245 0.338 - 553.8 1 2 0 -0.0009 11 0 0 0 2.61E+06 2.12E+06 - - - 3.7249 1 221125_WJC_METTL3_EV_vs_WT_F06.10784.10784.2 1.66E-09 19/30 K.TAADVVSPGANSVDSR.V sp|Q01804|OTUD4_HUMAN 1 1544.7431 1.82 80534 10784 2 1544.742753 773.3788 OTU domain-containing protein 4 OS=Homo sapiens OX=9606 GN=OTUD4 PE=1 SV=4 4.21 2106 - 4.29E+06 - - - -0.2013 - 3.421 0.641 - 1107.1 1 2 0 -0.0003 16 0 0 0 5.98E+07 3.29E+07 - - - 6.7992 0.9987 221125_WJC_METTL3_EV_vs_WT_F06.10785.10785.3 0.0452 Dec-36 R.SSPQLDPLRK.S sp|Q8ND56|LS14A_HUMAN 1 1139.6299 0.95 80535 10785 3 1139.628931 380.8839 Protein LSM14 homolog A OS=Homo sapiens OX=9606 GN=LSM14A PE=1 SV=3 8.46 2106 - 4.44E+06 - - - -0.8257 - 1.865 0.25 - 258.3 1 2 0 -0.0009 10 0 0 0 4.48E+08 4.69E+08 - - - 3.1472 1 221125_WJC_METTL3_EV_vs_WT_F06.10786.10786.3 1.88E-06 16/52 K.ITESVAETAQTIK[136.11]K.S sp|Q96A49|SYAP1_HUMAN 1 1525.8443 - 80536 10786 3 1525.845064 509.622 Synapse-associated protein 1 OS=Homo sapiens OX=9606 GN=SYAP1 PE=1 SV=1 6.14 2106 - 3.13E+06 - - - 0.5086 - 3.22 0.612 - 436.2 1 2 0 0.0008 14 0 0 0 - - - - - 8.4706 1 221125_WJC_METTL3_EV_vs_WT_F06.10790.10790.3 6.70E-07 Dec-44 K.SGSSFVHQASFK[136.11].F sp|P49792|RBP2_HUMAN 1 1288.6291 1.06 80540 10790 3 1288.628293 430.5503 E3 SUMO-protein ligase RanBP2 OS=Homo sapiens OX=9606 GN=RANBP2 PE=1 SV=2 8.49 2106.4 - 1.49E+06 - - - -0.665 - 2.401 0.55 - 209.9 1 2 0 -0.0009 12 0 0 0 1.98E+07 1.87E+07 - - - 7.0995 0.9996 221125_WJC_METTL3_EV_vs_WT_F06.10791.10791.2 0.000584 18-Sep R.SSPQLDPLR[166.11]K[136.11].S sp|Q8ND56|LS14A_HUMAN 1 1157.6523 1.04 80541 10791 2 1157.652769 579.8334 Protein LSM14 homolog A OS=Homo sapiens OX=9606 GN=LSM14A PE=1 SV=3 8.46 2106.5 - 1.46E+06 - - - 0.3688 - 1.638 0.395 - 234.5 1 2 0 0.0004 10 0 0 0 1.27E+08 1.22E+08 - - - 3.3358 0.997 221125_WJC_METTL3_EV_vs_WT_F06.10792.10792.3 0.0244 Oct-40 K.GIK[136.11]EEVQLTSK[136.11].Q sp|Q92616|GCN1_HUMAN 1 1246.7104 0.86 80542 10792 3 1246.708849 416.5774 eIF-2-alpha kinase activator GCN1 OS=Homo sapiens OX=9606 GN=GCN1 PE=1 SV=6 6.14 2106.6 - 1.38E+06 - - - -1.2176 - 1.982 0.288 - 173.9 1 2 1 -0.0015 11 0 0 0 9.46E+06 1.10E+07 - - - 3.6939 1 221125_WJC_METTL3_EV_vs_WT_F06.10793.10793.3 5.68E-08 19/64 R.AMIGHTDSAEAAPGTIR.G "sp|O00746|NDKM_HUMAN,tr|Q4TT34|Q4TT34_HUMAN,tr|A0A087WVT9|A0A087WVT9_HUMAN,tr|H0Y6J0|H0Y6J0_HUMAN,tr|F2Z2X0|F2Z2X0_HUMAN" 5 1696.8203 2.19 80543 10793 3 1696.819272 566.614 "Nucleoside diphosphate kinase, mitochondrial OS=Homo sapiens OX=9606 GN=NME4 PE=1 SV=1" 5.32 2106.6 - 1.34E+06 - - - -0.5876 - 3.552 0.625 - 366.2 1 2 0 -0.001 17 0 0 0 7.87E+08 3.59E+08 - - - 8.71 0.8846 221125_WJC_METTL3_EV_vs_WT_F06.10795.10795.2 0.0117 22-Nov T.ESVAETAQTIKK.S sp|Q96A49|SYAP1_HUMAN 1 1303.6983 1.43 80545 10795 2 1303.699537 652.8564 Synapse-associated protein 1 OS=Homo sapiens OX=9606 GN=SYAP1 PE=1 SV=1 6.24 2106.7 - 1.16E+07 - - - 0.9136 - 1.365 0.279 - 155.3 1 1 0 0.0012 12 0 0 0 1.85E+07 1.29E+07 - - - 1.92 1 221125_WJC_METTL3_EV_vs_WT_F06.10797.10797.2 5.15E-08 17/26 R.LEDSSNQVTQAVAK.L sp|P46939|UTRN_HUMAN 1 1488.742 2.57 80547 10797 2 1488.745906 745.3783 Utrophin OS=Homo sapiens OX=9606 GN=UTRN PE=1 SV=2 4.37 2107 - 642666 - - - 2.623 - 3.424 0.616 - 1193.2 1 2 0 0.0039 14 0 0 0 4.28E+06 1.66E+06 - - - 6.6782 0.9625 221125_WJC_METTL3_EV_vs_WT_F06.10799.10799.3 0.917 Jul-40 K.C[160.03]QLMASVTSHK[136.11].S "sp|Q68CZ6|HAUS3_HUMAN,tr|A0A5F9ZHQ7|A0A5F9ZHQ7_HUMAN" 2 1268.6097 0.05 80549 10799 3 1268.608475 423.8772 HAUS augmin-like complex subunit 3 OS=Homo sapiens OX=9606 GN=HAUS3 PE=1 SV=1 8.23 2107.3 - 596401 - - - -0.9475 - 1.257 0.177 - 43.8 2 2 0 -0.0012 11 0 0 0 1.18E+06 2.31E+07 - - - 1.0235 1 221125_WJC_METTL3_EV_vs_WT_F06.10806.10806.3 1.56E-08 18/64 R.AMIGHTDSAEAAPGTIR[166.11].G "sp|O00746|NDKM_HUMAN,tr|Q4TT34|Q4TT34_HUMAN,tr|A0A087WVT9|A0A087WVT9_HUMAN,tr|H0Y6J0|H0Y6J0_HUMAN,tr|F2Z2X0|F2Z2X0_HUMAN" 5 1706.8285 2.19 80555 10806 3 1706.825693 569.9501 "Nucleoside diphosphate kinase, mitochondrial OS=Homo sapiens OX=9606 GN=NME4 PE=1 SV=1" 5.32 2108 - 5.60E+06 - - - -1.6674 - 3.23 0.644 - 296.3 1 2 0 -0.0028 17 0 0 0 7.86E+08 3.59E+08 - - - 8.6812 0.9999 221125_WJC_METTL3_EV_vs_WT_F06.10807.10807.3 0.000549 13/40 K.C[160.03]EAVIGHFNGK.F "sp|P29558|RBMS1_HUMAN,tr|E7ETU5|E7ETU5_HUMAN,tr|F6Y5H0|F6Y5H0_HUMAN" 3 1230.5815 1.73 80556 10807 3 1230.579697 411.2011 "RNA-binding motif, single-stranded-interacting protein 1 OS=Homo sapiens OX=9606 GN=RBMS1 PE=1 SV=3" 6.74 2108 - 4.93E+06 - - - -1.4993 - 2.551 0.432 - 298 1 2 0 -0.0018 11 0 0 0 1.40E+08 8.11E+07 - - - 6.0163 1 221125_WJC_METTL3_EV_vs_WT_F06.10808.10808.2 9.89E-09 13/26 K.GDATVSYEDPPTAK[136.11].A "sp|Q01844|EWS_HUMAN,tr|B0QYK0|B0QYK0_HUMAN,tr|H7BY36|H7BY36_HUMAN,tr|A0A0D9SFL3|A0A0D9SFL3_HUMAN,tr|C9JGE3|C9JGE3_HUMAN" 5 1457.6766 0.71 80557 10808 2 1457.675384 729.8456 RNA-binding protein EWS OS=Homo sapiens OX=9606 GN=EWSR1 PE=1 SV=1 4.03 2108.1 - 3.39E+06 - - - -0.8026 - 2.313 0.632 - 308.2 1 2 0 -0.0012 14 0 0 0 1.72E+09 2.41E+09 - - - 5.8129 1 221125_WJC_METTL3_EV_vs_WT_F06.10810.10810.3 2.29E-05 14/40 K.C[160.03]EAVIGHFNGK[136.11].F "sp|P29558|RBMS1_HUMAN,tr|E7ETU5|E7ETU5_HUMAN,tr|F6Y5H0|F6Y5H0_HUMAN" 3 1238.5957 1.72 80559 10810 3 1238.593839 413.8725 "RNA-binding motif, single-stranded-interacting protein 1 OS=Homo sapiens OX=9606 GN=RBMS1 PE=1 SV=3" 6.74 2108.2 - 3.14E+06 - - - -1.5364 - 2.558 0.503 - 282.5 1 2 0 -0.0019 11 0 0 0 1.40E+08 8.14E+07 - - - 6.8156 1 221125_WJC_METTL3_EV_vs_WT_F06.10812.10812.2 2.47E-12 16/26 R.DGMDNQGGYGSVGR.M sp|P31942|HNRH3_HUMAN 1 1411.5786 1.88 80561 10812 2 1411.57811 706.7966 Heterogeneous nuclear ribonucleoprotein H3 OS=Homo sapiens OX=9606 GN=HNRNPH3 PE=1 SV=2 4.21 2108.4 - 1.74E+06 - - - -0.3762 - 3.214 0.751 - 857.2 1 2 0 -0.0005 14 0 0 0 9.20E+07 4.88E+07 - - - 7.5175 1 221125_WJC_METTL3_EV_vs_WT_F06.10813.10813.2 1.87E-05 16/28 K.NLQEGNEVDSQSSIR[166.11].T "sp|O75152|ZC11A_HUMAN,tr|E9PQ61|E9PQ61_HUMAN" 2 1684.7892 1.12 80562 10813 2 1684.786071 843.4019 Zinc finger CCCH domain-containing protein 11A OS=Homo sapiens OX=9606 GN=ZC3H11A PE=1 SV=3 4.14 2108.5 - 1.63E+06 - - - -1.843 - 3.006 0.54 - 939.6 1 2 0 -0.0031 15 0 0 0 1.22E+07 1.09E+07 - - - 5.7344 1 221125_WJC_METTL3_EV_vs_WT_F06.10814.10814.2 5.92E-07 16/28 K.NLQEGNEVDSQSSIR.T "sp|O75152|ZC11A_HUMAN,tr|E9PQ61|E9PQ61_HUMAN" 2 1674.7809 1.12 80563 10814 2 1674.778203 838.3977 Zinc finger CCCH domain-containing protein 11A OS=Homo sapiens OX=9606 GN=ZC3H11A PE=1 SV=3 4.14 2108.6 - 1.47E+06 - - - -1.6139 - 2.954 0.642 - 867.9 1 2 0 -0.0027 15 0 0 0 1.22E+07 1.09E+07 - - - 6.445 1 221125_WJC_METTL3_EV_vs_WT_F06.10815.10815.3 1.67E-05 17/48 R.EDLQLDKPASGVK.E "sp|P78347|GTF2I_HUMAN,tr|A0A494C0Q7|A0A494C0Q7_HUMAN,tr|A0A494C1K3|A0A494C1K3_HUMAN" 3 1398.7355 1.59 80564 10815 3 1398.735377 467.2524 General transcription factor II-I OS=Homo sapiens OX=9606 GN=GTF2I PE=1 SV=2 4.56 2108.7 - 1.45E+06 - - - -0.0586 - 2.79 0.493 - 375.1 1 2 0 -0.0001 13 0 0 0 2.69E+09 1.69E+09 - - - 6.8183 0.9998 221125_WJC_METTL3_EV_vs_WT_F06.10816.10816.2 0.059 24-Nov K.TTPEC[160.03]GPTGYVEK.L sp|O76095|JTB_HUMAN 1 1437.6446 3.79 80565 10816 2 1437.643594 719.8296 Protein JTB OS=Homo sapiens OX=9606 GN=JTB PE=1 SV=1 4.53 2108.8 - 1.18E+06 - - - -0.697 - 2.178 0.419 - 397.5 1 2 0 -0.001 13 0 0 0 3.33E+07 8.80E+06 - - - 4.1332 0.9999 221125_WJC_METTL3_EV_vs_WT_F06.10819.10819.3 5.30E-05 Nov-56 K.NLQEGNEVDSQSSIR[166.11].T "sp|O75152|ZC11A_HUMAN,tr|E9PQ61|E9PQ61_HUMAN" 2 1684.7892 1.52 80568 10819 3 1684.787296 562.6037 Zinc finger CCCH domain-containing protein 11A OS=Homo sapiens OX=9606 GN=ZC3H11A PE=1 SV=3 4.14 2109.2 - 739910 - - - -1.1159 - 2.193 0.434 - 195.9 1 2 0 -0.0019 15 0 0 0 3.73E+06 2.45E+06 - - - 5.4272 1 221125_WJC_METTL3_EV_vs_WT_F06.10820.10820.2 9.74E-05 14/28 R.NDAPTPGTSTTPGLR.S "sp|Q04726|TLE3_HUMAN,tr|A0A0D9SES8|A0A0D9SES8_HUMAN,tr|H0YL70|H0YL70_HUMAN,tr|H0YKN8|H0YKN8_HUMAN,tr|H0YKT5|H0YKT5_HUMAN,tr|H0YLW9|H0YLW9_HUMAN,tr|H0YLI3|H0YLI3_HUMAN,tr|H0YKH0|H0YKH0_HUMAN,tr|H0YNT2|H0YNT2_HUMAN" 9 1483.7267 1.41 80569 10820 2 1483.727106 742.8706 Transducin-like enhancer protein 3 OS=Homo sapiens OX=9606 GN=TLE3 PE=1 SV=2 5.84 2109.3 - 458774 - - - 0.2831 - 2.572 0.598 - 595.8 1 2 0 0.0004 15 0 0 0 5.62E+07 3.99E+07 - - - 5.7802 1 221125_WJC_METTL3_EV_vs_WT_F06.10823.10823.3 1.72E-06 16/44 K.SGSSFVHQASFK.F sp|P49792|RBP2_HUMAN 1 1280.6149 1.05 80571 10823 3 1280.61233 427.8789 E3 SUMO-protein ligase RanBP2 OS=Homo sapiens OX=9606 GN=RANBP2 PE=1 SV=2 8.49 2109.6 - 2.21E+06 - - - -2.0459 - 3.154 0.536 - 387.8 1 2 0 -0.0026 12 0 0 0 1.98E+07 1.89E+07 - - - 7.6991 0.9999 221125_WJC_METTL3_EV_vs_WT_F06.10825.10825.3 6.59E-07 16/48 R.EDLQLDK[136.11]PASGVK[136.11].E "sp|P78347|GTF2I_HUMAN,tr|A0A494C0Q7|A0A494C0Q7_HUMAN,tr|A0A494C1K3|A0A494C1K3_HUMAN" 3 1414.7639 1.59 80572 10825 3 1414.763172 472.5952 General transcription factor II-I OS=Homo sapiens OX=9606 GN=GTF2I PE=1 SV=2 4.56 2109.8 - 1.40E+07 - - - -0.4856 - 2.613 0.343 - 365.8 1 2 0 -0.0007 13 0 0 0 2.69E+09 1.69E+09 - - - 4.9681 1 221125_WJC_METTL3_EV_vs_WT_F06.10826.10826.2 2.12E-08 14/26 R.DGMDNQGGYGSVGR[166.11].M sp|P31942|HNRH3_HUMAN 1 1421.5869 1.88 80573 10826 2 1421.587581 711.8007 Heterogeneous nuclear ribonucleoprotein H3 OS=Homo sapiens OX=9606 GN=HNRNPH3 PE=1 SV=2 4.21 2109.9 - 2.84E+06 - - - 0.4713 - 2.102 0.674 - 506.8 1 2 0 0.0007 14 0 0 0 9.20E+07 4.88E+07 - - - 5.8832 1 221125_WJC_METTL3_EV_vs_WT_F06.10827.10827.2 1.09E-13 15/18 R.HC[160.03]NMVLENVK[136.11].E sp|P62316|SMD2_HUMAN 1 1250.5991 1.11 80574 10827 2 1250.595961 626.3068 Small nuclear ribonucleoprotein Sm D2 OS=Homo sapiens OX=9606 GN=SNRPD2 PE=1 SV=1 6.74 2110 - 2.45E+06 - - - -2.5204 - 3.116 0.549 - 650.1 1 2 0 -0.0032 10 0 0 0 6.00E+07 5.38E+07 - - - 6.2674 1 221125_WJC_METTL3_EV_vs_WT_F06.10829.10829.2 3.45E-08 16/18 R.HC[160.03]NMVLENVK.E sp|P62316|SMD2_HUMAN 1 1242.5849 1.09 80576 10829 2 1242.583893 622.2997 Small nuclear ribonucleoprotein Sm D2 OS=Homo sapiens OX=9606 GN=SNRPD2 PE=1 SV=1 6.74 2110.1 - 1.83E+06 - - - -0.8209 - 2.924 0.517 - 835.8 1 2 0 -0.001 10 0 0 0 6.19E+07 5.66E+07 - - - 5.8542 1 221125_WJC_METTL3_EV_vs_WT_F06.10830.10830.2 0.000209 13/20 K.C[160.03]EAVIGHFNGK.F "sp|P29558|RBMS1_HUMAN,tr|E7ETU5|E7ETU5_HUMAN,tr|F6Y5H0|F6Y5H0_HUMAN" 3 1230.5815 2.58 80577 10830 2 1230.580358 616.298 "RNA-binding motif, single-stranded-interacting protein 1 OS=Homo sapiens OX=9606 GN=RBMS1 PE=1 SV=3" 6.74 2110.2 - 1.46E+06 - - - -0.9621 - 2.621 0.581 - 745.6 1 2 0 -0.0012 11 0 0 0 5.31E+07 2.06E+07 - - - 5.9385 0.9999 221125_WJC_METTL3_EV_vs_WT_F06.10836.10836.3 0.000359 Sep-36 R.HC[160.03]NMVLENVK[136.11].E sp|P62316|SMD2_HUMAN 1 1250.5991 1.03 80581 10836 3 1250.597675 417.8736 Small nuclear ribonucleoprotein Sm D2 OS=Homo sapiens OX=9606 GN=SNRPD2 PE=1 SV=1 6.74 2110.9 - 1.98E+06 - - - -1.1498 - 2.044 0.433 - 172.1 1 2 0 -0.0014 10 0 0 0 3.35E+07 3.25E+07 - - - 5.455 1 221125_WJC_METTL3_EV_vs_WT_F06.10838.10838.2 1.66E-16 23/32 R.AMIGHTDSAEAAPGTIR.G "sp|O00746|NDKM_HUMAN,tr|Q4TT34|Q4TT34_HUMAN,tr|A0A087WVT9|A0A087WVT9_HUMAN,tr|H0Y6J0|H0Y6J0_HUMAN,tr|F2Z2X0|F2Z2X0_HUMAN" 5 1696.8203 2.98 80583 10838 2 1696.82135 849.4174 "Nucleoside diphosphate kinase, mitochondrial OS=Homo sapiens OX=9606 GN=NME4 PE=1 SV=1" 5.32 2111.1 - 1.98E+06 - - - 0.6371 - 3.968 0.745 - 1755.8 1 2 0 0.0011 17 0 0 0 4.34E+07 1.46E+07 - - - 7.9318 0.9999 221125_WJC_METTL3_EV_vs_WT_F06.10839.10839.3 2.86E-06 15/44 R.GSNK[136.11]LVIEEAER[166.11].S sp|P50991|TCPD_HUMAN 1 1361.727 0.37 80584 10839 3 1361.724985 454.9163 T-complex protein 1 subunit delta OS=Homo sapiens OX=9606 GN=CCT4 PE=1 SV=4 4.79 2111.2 - 1.97E+06 - - - -1.4533 - 2.792 0.499 - 453.6 1 2 1 -0.002 12 0 0 0 3.54E+07 9.54E+07 - - - 6.9488 0.9999 221125_WJC_METTL3_EV_vs_WT_F06.10840.10840.2 0.000171 17/24 K.DVTEAEQAEEQAR.Q "sp|Q12788|TBL3_HUMAN,tr|J3KNP2|J3KNP2_HUMAN" 2 1474.6536 1.49 80585 10840 2 1474.651338 738.3341 Transducin beta-like protein 3 OS=Homo sapiens OX=9606 GN=TBL3 PE=1 SV=2 3.91 2111.4 - 1.32E+06 - - - -1.5204 - 3.171 0.483 - 1305.9 1 2 0 -0.0022 13 0 0 0 2.64E+07 1.77E+07 - - - 5.5696 0.9997 221125_WJC_METTL3_EV_vs_WT_F06.10843.10843.2 0.0115 20-Dec R.HYGESITNIGK[136.11].A "sp|Q8NEL9|DDHD1_HUMAN,tr|A0A6E1W401|A0A6E1W401_HUMAN,tr|A0A087X0H7|A0A087X0H7_HUMAN,tr|A0A669KAW5|A0A669KAW5_HUMAN,tr|A0A669KB51|A0A669KB51_HUMAN" 5 1225.6183 1.65 80588 10843 2 1225.619127 613.8164 Phospholipase DDHD1 OS=Homo sapiens OX=9606 GN=DDHD1 PE=1 SV=2 6.75 2111.8 - 562855 - - - 0.7147 - 2.19 0.368 - 278.5 1 2 0 0.0009 11 0 0 0 1.03E+07 6.21E+06 - - - 3.8794 0.9998 221125_WJC_METTL3_EV_vs_WT_F06.10846.10846.2 8.62E-05 24-Oct R.EDLQLDK[136.11]PASGVK[136.11].E "sp|P78347|GTF2I_HUMAN,tr|A0A494C0Q7|A0A494C0Q7_HUMAN,tr|A0A494C1K3|A0A494C1K3_HUMAN" 3 1414.7639 1.58 80589 10846 2 1414.762112 708.3892 General transcription factor II-I OS=Homo sapiens OX=9606 GN=GTF2I PE=1 SV=2 4.56 2112.1 - 6.52E+06 - - - -1.2348 - 2.317 0.471 - 363.4 1 2 0 -0.0017 13 0 0 0 4.02E+08 2.54E+08 - - - 4.6758 0.9999 221125_WJC_METTL3_EV_vs_WT_F06.10848.10848.2 3.26E-05 24-Dec R.EDLQLDKPASGVK.E "sp|P78347|GTF2I_HUMAN,tr|A0A494C0Q7|A0A494C0Q7_HUMAN,tr|A0A494C1K3|A0A494C1K3_HUMAN" 3 1398.7355 1.58 80591 10848 2 1398.734663 700.375 General transcription factor II-I OS=Homo sapiens OX=9606 GN=GTF2I PE=1 SV=2 4.56 2112.2 - 8.16E+06 - - - -0.5691 - 2.556 0.555 - 578.5 1 2 0 -0.0008 13 0 0 0 4.02E+08 2.54E+08 - - - 5.5485 1 221125_WJC_METTL3_EV_vs_WT_F06.10852.10852.2 6.14E-13 23/32 R.AMIGHTDSAEAAPGTIR[166.11].G "sp|O00746|NDKM_HUMAN,tr|Q4TT34|Q4TT34_HUMAN,tr|A0A087WVT9|A0A087WVT9_HUMAN,tr|H0Y6J0|H0Y6J0_HUMAN,tr|F2Z2X0|F2Z2X0_HUMAN" 5 1706.8285 2.98 80595 10852 2 1706.825965 854.4215 "Nucleoside diphosphate kinase, mitochondrial OS=Homo sapiens OX=9606 GN=NME4 PE=1 SV=1" 5.32 2112.6 - 1.39E+06 - - - -1.5081 - 3.697 0.688 - 1917.9 1 2 0 -0.0026 17 0 0 0 4.34E+07 1.46E+07 - - - 7.3364 0.999 221125_WJC_METTL3_EV_vs_WT_F06.10853.10853.2 0.146 16-Oct K.K[136.11]EDINLSVR[166.11].K "sp|Q15645|PCH2_HUMAN,tr|H0YAL2|H0YAL2_HUMAN" 2 1090.6101 0.83 80596 10853 2 1090.607224 546.3123 Pachytene checkpoint protein 2 homolog OS=Homo sapiens OX=9606 GN=TRIP13 PE=1 SV=2 6.07 2112.8 - 1.09E+06 - - - -2.6765 - 1.952 0.356 - 347.5 1 2 0 -0.0029 9 0 0 0 7.14E+06 8.61E+06 - - - 3.6045 0.9493 221125_WJC_METTL3_EV_vs_WT_F06.10860.10860.3 0.215 Dec-44 R.TAVSGIRPENLK.Q sp|Q9GZR2|REXO4_HUMAN 1 1283.7197 1.7 80602 10860 3 1283.717994 428.9139 RNA exonuclease 4 OS=Homo sapiens OX=9606 GN=REXO4 PE=1 SV=2 8.41 2113.6 - 1.33E+06 - - - -1.3679 - 2.028 0.053 - 158.7 2 2 0 -0.0018 12 0 0 0 1.69E+07 9.96E+06 - - - 0.9509 1 221125_WJC_METTL3_EV_vs_WT_F06.10861.10861.2 1.46E-11 14/24 R.IC[160.03]DEC[160.03]NYGSYQGR[166.11].C sp|Q7RTV0|PHF5A_HUMAN 1 1630.638 1.08 80603 10861 2 1630.637873 816.3263 PHD finger-like domain-containing protein 5A OS=Homo sapiens OX=9606 GN=PHF5A PE=1 SV=1 4.37 2113.8 - 990420 - - - -0.054 - 3.164 0.767 - 817.8 1 2 0 -0.0001 13 0 0 0 4.13E+07 3.83E+07 - - - 7.6623 0.9896 221125_WJC_METTL3_EV_vs_WT_F06.10862.10862.2 0.000286 22-Dec E.DLQLDK[136.11]PASGVK[136.11].E "sp|P78347|GTF2I_HUMAN,tr|A0A494C0Q7|A0A494C0Q7_HUMAN,tr|A0A494C1K3|A0A494C1K3_HUMAN" 3 1285.7213 1.63 80604 10862 2 1285.722639 643.8679 General transcription factor II-I OS=Homo sapiens OX=9606 GN=GTF2I PE=1 SV=2 5.96 2113.9 - 685616 - - - 1.0679 - 2.379 0.464 - 538.4 1 1 0 0.0014 12 0 0 0 1.82E+07 1.12E+07 - - - 4.7481 1 221125_WJC_METTL3_EV_vs_WT_F06.10865.10865.2 2.57E-06 20-Oct R.SQYEQLAEQNR.K "sp|P13645|K1C10_HUMAN,tr|A0A1B0GVI3|A0A1B0GVI3_HUMAN" 2 1364.6321 17077.36 80605 10865 2 1364.630673 683.3233 "Keratin, type I cytoskeletal 10 OS=Homo sapiens OX=9606 GN=KRT10 PE=1 SV=6" 4.53 2114.3 - 3.22E+07 - - - -1.0142 - 2.377 0.603 - 367.9 1 2 0 -0.0014 11 0 0 0 5.28E+09 3.09E+05 - - - 5.8366 0.9994 221125_WJC_METTL3_EV_vs_WT_F06.10870.10870.2 2.19E-06 13/28 R.NDAPTPGTSTTPGLR[166.11].S "sp|Q04726|TLE3_HUMAN,tr|A0A0D9SES8|A0A0D9SES8_HUMAN,tr|H0YL70|H0YL70_HUMAN,tr|H0YKN8|H0YKN8_HUMAN,tr|H0YKT5|H0YKT5_HUMAN,tr|H0YLW9|H0YLW9_HUMAN,tr|H0YLI3|H0YLI3_HUMAN,tr|H0YKH0|H0YKH0_HUMAN,tr|H0YNT2|H0YNT2_HUMAN" 9 1493.735 1.42 80610 10870 2 1493.729839 747.8748 Transducin-like enhancer protein 3 OS=Homo sapiens OX=9606 GN=TLE3 PE=1 SV=2 5.84 2114.7 - 2.11E+06 - - - -3.4256 - 2.395 0.579 - 441.3 1 2 0 -0.0051 15 0 0 0 5.62E+07 3.95E+07 - - - 5.4631 1 221125_WJC_METTL3_EV_vs_WT_F06.10872.10872.2 6.06E-12 14/24 R.IC[160.03]DEC[160.03]NYGSYQGR.C sp|Q7RTV0|PHF5A_HUMAN 1 1620.6297 1.08 80612 10872 2 1620.626048 811.3221 PHD finger-like domain-containing protein 5A OS=Homo sapiens OX=9606 GN=PHF5A PE=1 SV=1 4.37 2115 - 1.34E+06 - - - -2.2479 - 3.079 0.825 - 901.7 1 2 0 -0.0036 13 0 0 0 4.13E+07 3.83E+07 - - - 8.0196 0.9791 221125_WJC_METTL3_EV_vs_WT_F06.10873.10873.2 1.94E-05 13/22 E.DLQLDKPASGVK.E "sp|P78347|GTF2I_HUMAN,tr|A0A494C0Q7|A0A494C0Q7_HUMAN,tr|A0A494C1K3|A0A494C1K3_HUMAN" 3 1269.6929 1.63 80613 10873 2 1269.694033 635.8537 General transcription factor II-I OS=Homo sapiens OX=9606 GN=GTF2I PE=1 SV=2 5.96 2115.1 - 923458 - - - 0.9191 - 2.442 0.308 - 569.5 1 1 0 0.0012 12 0 0 0 1.82E+07 1.12E+07 - - - 3.6647 0.9967 221125_WJC_METTL3_EV_vs_WT_F06.10878.10878.3 0.00203 Sep-40 R.SQYEQLAEQNR.K "sp|P13645|K1C10_HUMAN,tr|A0A1B0GVI3|A0A1B0GVI3_HUMAN" 2 1364.6321 2013.14 80616 10878 3 1364.631127 455.8846 "Keratin, type I cytoskeletal 10 OS=Homo sapiens OX=9606 GN=KRT10 PE=1 SV=6" 4.53 2115.7 - 1.21E+07 - - - -0.6815 - 1.871 0.196 - 153.3 1 2 0 -0.0009 11 0 0 0 6.00E+08 2.98E+05 - - - 2.5047 0.9999 221125_WJC_METTL3_EV_vs_WT_F06.10879.10879.3 0.000172 Dec-48 R.EDLQLDKPASGVK[136.11].E "sp|P78347|GTF2I_HUMAN,tr|A0A494C0Q7|A0A494C0Q7_HUMAN,tr|A0A494C1K3|A0A494C1K3_HUMAN" 3 1406.7497 - 80617 10879 3 1406.750386 469.9238 General transcription factor II-I OS=Homo sapiens OX=9606 GN=GTF2I PE=1 SV=2 4.56 2115.7 - 2.74E+06 - - - 0.5168 - 2.198 0.374 - 173.5 1 2 0 0.0007 13 0 0 0 - - - - - 4.8448 0.9999 221125_WJC_METTL3_EV_vs_WT_F06.10886.10886.2 2.81E-06 13/22 K.LGSTEVASNVPK.V "sp|Q9Y5A9|YTHD2_HUMAN,tr|S4R3V3|S4R3V3_HUMAN" 2 1200.635 1.75 80622 10886 2 1200.634699 601.3248 YTH domain-containing family protein 2 OS=Homo sapiens OX=9606 GN=YTHDF2 PE=1 SV=2 6 2116.4 - 1.06E+06 - - - -0.2649 - 2.574 0.469 - 519.9 1 2 0 -0.0003 12 0 0 0 2.22E+07 1.27E+07 - - - 4.9926 0.927 221125_WJC_METTL3_EV_vs_WT_F06.10887.10887.3 0.00293 Nov-40 A.TTHWVVTEDGK.L "sp|Q96AE7|TTC17_HUMAN,tr|E9PN79|E9PN79_HUMAN" 2 1271.6146 1.54 80623 10887 3 1271.61214 424.8788 Tetratricopeptide repeat protein 17 OS=Homo sapiens OX=9606 GN=TTC17 PE=1 SV=1 5.29 2116.6 - 682117 - - - -1.9471 - 1.862 0.326 - 185.4 1 1 0 -0.0025 11 0 0 0 1.15E+07 7.51E+06 - - - 3.9399 0.9998 221125_WJC_METTL3_EV_vs_WT_F06.10896.10896.2 0.000428 20-Nov R.ISSVLAGGSC[160.03]R.A "sp|P02533|K1C14_HUMAN,sp|P08779|K1C16_HUMAN,tr|K7ENV3|K7ENV3_HUMAN" 3 1105.555 999 80630 10896 2 1105.553401 553.7848 "Keratin, type I cytoskeletal 14 OS=Homo sapiens OX=9606 GN=KRT14 PE=1 SV=4" 8.25 2117.4 - 2.02E+06 - - - -1.44 - 2.273 0.441 - 448.3 1 2 0 -0.0016 11 0 0 0 3.60E+07 0.00E+00 - - - 4.519 0.9795 221125_WJC_METTL3_EV_vs_WT_F06.10899.10899.2 0.000729 18-Oct L.QLDK[136.11]PASGVK[136.11].E "sp|P78347|GTF2I_HUMAN,tr|A0A494C0Q7|A0A494C0Q7_HUMAN,tr|A0A494C1K3|A0A494C1K3_HUMAN" 3 1057.6103 2.21 80633 10899 2 1057.608988 529.8124 General transcription factor II-I OS=Homo sapiens OX=9606 GN=GTF2I PE=1 SV=2 8.59 2117.8 - 546763 - - - -1.2018 - 1.846 0.402 - 346.6 1 1 0 -0.0013 10 0 0 0 2.34E+07 1.06E+07 - - - 3.7209 0.9996 221125_WJC_METTL3_EV_vs_WT_F06.10904.10904.3 0.0157 Sep-36 K.R[166.11]GDTYELQVR[166.11].G "sp|Q9H0U3|MAGT1_HUMAN,tr|A0A087WU53|A0A087WU53_HUMAN" 2 1255.6424 0.39 80636 10904 3 1255.639133 419.5547 Magnesium transporter protein 1 OS=Homo sapiens OX=9606 GN=MAGT1 PE=1 SV=1 6.07 2118.4 - 2.03E+06 - - - -2.5931 - 1.898 0.402 - 97.4 1 2 0 -0.0033 10 0 0 0 3.75E+07 9.63E+07 - - - 4.8924 0.9996 221125_WJC_METTL3_EV_vs_WT_F06.10905.10905.3 0.00324 Nov-36 K.DHNIPGELER[166.11].Q sp|P35580|MYH10_HUMAN 1 1188.5763 0.93 80637 10905 3 1188.576506 397.1994 Myosin-10 OS=Homo sapiens OX=9606 GN=MYH10 PE=1 SV=3 4.65 2118.6 - 832816 - - - 0.1986 - 2.013 0.309 - 249.9 1 2 0 0.0002 10 0 0 0 5.01E+07 5.39E+07 - - - 4.0282 0.9998 221125_WJC_METTL3_EV_vs_WT_F06.10907.10907.2 8.99E-06 30-Dec K.VTAPQPAATNGDLASR[166.11].S "sp|P98194|AT2C1_HUMAN,tr|H0Y9V7|H0Y9V7_HUMAN,tr|B4E2Q0|B4E2Q0_HUMAN" 3 1577.8037 1.21 80639 10907 2 1577.802105 789.9091 Calcium-transporting ATPase type 2C member 1 OS=Homo sapiens OX=9606 GN=ATP2C1 PE=1 SV=3 5.81 2118.8 - 597463 - - - -1.0134 - 2.181 0.475 - 210.9 1 2 0 -0.0016 16 0 0 0 2.04E+07 1.69E+07 - - - 4.466 0.9999 221125_WJC_METTL3_EV_vs_WT_F06.10914.10914.3 2.88E-05 14/48 K.FWETDESSK[136.11]DGPK[136.11].G "sp|Q14671|PUM1_HUMAN,tr|Q5T1Z8|Q5T1Z8_HUMAN,tr|H0YEH2|H0YEH2_HUMAN,tr|Q5T1Z4|Q5T1Z4_HUMAN" 4 1540.7017 2.44 80643 10914 3 1540.698719 514.5745 Pumilio homolog 1 OS=Homo sapiens OX=9606 GN=PUM1 PE=1 SV=3 4.32 2119.6 - 3.74E+06 - - - -1.9043 - 2.747 0.542 - 194.7 1 2 1 -0.0029 13 0 0 0 3.57E+08 1.46E+08 - - - 7.3217 0.9997 221125_WJC_METTL3_EV_vs_WT_F06.10916.10916.3 3.46E-08 14/36 K.RGDTYELQVR.G "sp|Q9H0U3|MAGT1_HUMAN,tr|A0A087WU53|A0A087WU53_HUMAN" 2 1235.6258 0.44 80645 10916 3 1235.621502 412.8826 Magnesium transporter protein 1 OS=Homo sapiens OX=9606 GN=MAGT1 PE=1 SV=1 6.07 2119.8 - 1.34E+06 - - - -3.5181 - 2.785 0.382 - 336.4 1 2 0 -0.0043 10 0 0 0 3.56E+07 8.14E+07 - - - 5.789 1 221125_WJC_METTL3_EV_vs_WT_F06.10923.10923.3 1.19E-07 Dec-40 K.LC[160.03]DSYEIRPGK.H "sp|O43390|HNRPR_HUMAN,tr|B4DT28|B4DT28_HUMAN,tr|A0A6Q8PH31|A0A6Q8PH31_HUMAN,tr|A0A6Q8PEX7|A0A6Q8PEX7_HUMAN" 4 1336.6445 0.88 80651 10923 3 1336.643367 446.5555 Heterogeneous nuclear ribonucleoprotein R OS=Homo sapiens OX=9606 GN=HNRNPR PE=1 SV=1 6.06 2120.6 - 4.50E+06 - - - -0.8746 - 2.295 0.574 - 267.4 1 2 0 -0.0012 11 0 0 0 8.38E+07 9.48E+07 - - - 7.2992 0.9999 221125_WJC_METTL3_EV_vs_WT_F06.10926.10926.3 4.98E-06 13/44 R.NHLLESEDSYTR.E "sp|Q15643|TRIPB_HUMAN,tr|H0YJI2|H0YJI2_HUMAN,tr|H0YJ97|H0YJ97_HUMAN" 3 1462.6688 1.25 80653 10926 3 1462.663929 488.5636 Thyroid receptor-interacting protein 11 OS=Homo sapiens OX=9606 GN=TRIP11 PE=1 SV=3 4.65 2120.9 - 2.95E+06 - - - -3.3548 - 2.712 0.607 - 400.8 1 2 0 -0.0049 12 0 0 0 2.48E+08 1.99E+08 - - - 8.0715 0.9939 221125_WJC_METTL3_EV_vs_WT_F06.10927.10927.2 0.114 18-Aug R.SSPQLDPLRK.S sp|Q8ND56|LS14A_HUMAN 1 1139.6299 1.04 80654 10927 2 1139.628127 570.8222 Protein LSM14 homolog A OS=Homo sapiens OX=9606 GN=LSM14A PE=1 SV=3 8.46 2121 - 2.07E+06 - - - -1.5312 - 1.419 0.173 - 150.1 1 2 0 -0.0017 10 0 0 0 1.27E+08 1.22E+08 - - - 1.2951 0.9995 221125_WJC_METTL3_EV_vs_WT_F06.10928.10928.2 0.00123 18-Dec K.R[166.11]GDTYELQVR[166.11].G "sp|Q9H0U3|MAGT1_HUMAN,tr|A0A087WU53|A0A087WU53_HUMAN" 2 1255.6424 0.75 80655 10928 2 1255.644791 628.8285 Magnesium transporter protein 1 OS=Homo sapiens OX=9606 GN=MAGT1 PE=1 SV=1 6.07 2121.1 - 1.42E+06 - - - 1.913 - 2.111 0.376 - 211.8 1 2 0 0.0024 10 0 0 0 1.96E+07 2.62E+07 - - - 3.9029 1 221125_WJC_METTL3_EV_vs_WT_F06.10929.10929.2 1.17E-08 14/24 K.FWETDESSKDGPK.G "sp|Q14671|PUM1_HUMAN,tr|Q5T1Z8|Q5T1Z8_HUMAN,tr|H0YEH2|H0YEH2_HUMAN,tr|Q5T1Z4|Q5T1Z4_HUMAN" 4 1524.6733 2.65 80656 10929 2 1524.678259 763.3439 Pumilio homolog 1 OS=Homo sapiens OX=9606 GN=PUM1 PE=1 SV=3 4.32 2121.3 - 1.11E+06 - - - 3.2833 - 2.748 0.619 - 582.6 1 2 1 0.005 13 0 0 0 4.00E+07 1.51E+07 - - - 6.2058 1 221125_WJC_METTL3_EV_vs_WT_F06.10934.10934.3 4.47E-07 Dec-44 R.NHLLESEDSYTR[166.11].E "sp|Q15643|TRIPB_HUMAN,tr|H0YJI2|H0YJI2_HUMAN,tr|H0YJ97|H0YJ97_HUMAN" 3 1472.6771 1.24 80659 10934 3 1472.675219 491.8996 Thyroid receptor-interacting protein 11 OS=Homo sapiens OX=9606 GN=TRIP11 PE=1 SV=3 4.65 2121.9 - 4.77E+06 - - - -1.2813 - 2.422 0.55 - 315.7 1 2 0 -0.0019 12 0 0 0 2.47E+08 1.99E+08 - - - 7.1234 0.9998 221125_WJC_METTL3_EV_vs_WT_F06.10936.10936.3 0.000796 19/36 R.NKLDHYAIIK.F "sp|P62750|RL23A_HUMAN,tr|H7BY10|H7BY10_HUMAN,tr|K7ERT8|K7ERT8_HUMAN,tr|A8MUS3|A8MUS3_HUMAN,tr|K7EJV9|K7EJV9_HUMAN" 5 1213.6819 0.64 80661 10936 3 1213.680673 405.5679 60S ribosomal protein L23a OS=Homo sapiens OX=9606 GN=RPL23A PE=1 SV=1 8.51 2122.1 - 1.32E+06 - - - -1.0176 - 2.921 0.394 - 408.6 1 2 1 -0.0012 10 0 0 0 7.37E+07 1.14E+08 - - - 6.0629 0.9938 221125_WJC_METTL3_EV_vs_WT_F06.10938.10938.2 0.000148 24-Oct K.FWETDESSK[136.11]DGPK[136.11].G "sp|Q14671|PUM1_HUMAN,tr|Q5T1Z8|Q5T1Z8_HUMAN,tr|H0YEH2|H0YEH2_HUMAN,tr|Q5T1Z4|Q5T1Z4_HUMAN" 4 1540.7017 2.65 80663 10938 2 1540.70647 771.3581 Pumilio homolog 1 OS=Homo sapiens OX=9606 GN=PUM1 PE=1 SV=3 4.32 2122.4 - 516622 - - - 3.1265 - 1.968 0.574 - 152.5 1 2 1 0.0048 13 0 0 0 4.00E+07 1.51E+07 - - - 5.0166 0.9998 221125_WJC_METTL3_EV_vs_WT_F06.10939.10939.2 1.56E-07 18-Oct K.DHNIPGELER[166.11].Q sp|P35580|MYH10_HUMAN 1 1188.5763 1.3 80664 10939 2 1188.574461 595.2954 Myosin-10 OS=Homo sapiens OX=9606 GN=MYH10 PE=1 SV=3 4.65 2122.5 - 504136 - - - -1.522 - 2.171 0.479 - 451.8 1 2 0 -0.0018 10 0 0 0 2.05E+07 1.58E+07 - - - 4.7421 0.9999 221125_WJC_METTL3_EV_vs_WT_F06.10943.10943.3 7.52E-05 16/36 R.NK[136.11]LDHYAIIK[136.11].F "sp|P62750|RL23A_HUMAN,tr|H7BY10|H7BY10_HUMAN,tr|K7ERT8|K7ERT8_HUMAN,tr|A8MUS3|A8MUS3_HUMAN,tr|K7EJV9|K7EJV9_HUMAN" 5 1229.7103 0.65 80666 10943 3 1229.708911 410.9107 60S ribosomal protein L23a OS=Homo sapiens OX=9606 GN=RPL23A PE=1 SV=1 8.51 2123 - 4.82E+06 - - - -1.136 - 2.886 0.509 - 329.3 1 2 1 -0.0014 10 0 0 0 7.40E+07 1.15E+08 - - - 7.3097 0.9999 221125_WJC_METTL3_EV_vs_WT_F06.10944.10944.2 1.27E-07 22-Nov R.NHLLESEDSYTR[166.11].E "sp|Q15643|TRIPB_HUMAN,tr|H0YJI2|H0YJI2_HUMAN,tr|H0YJ97|H0YJ97_HUMAN" 3 1472.6771 0.72 80667 10944 2 1472.676683 737.3458 Thyroid receptor-interacting protein 11 OS=Homo sapiens OX=9606 GN=TRIP11 PE=1 SV=3 4.65 2123.1 - 2.01E+06 - - - -0.2872 - 2.296 0.471 - 383.2 1 2 0 -0.0004 12 0 0 0 4.15E+07 5.79E+07 - - - 4.7066 0.9999 221125_WJC_METTL3_EV_vs_WT_F06.10945.10945.2 7.56E-05 15/18 K.RGDTYELQVR.G "sp|Q9H0U3|MAGT1_HUMAN,tr|A0A087WU53|A0A087WU53_HUMAN" 2 1235.6258 0.74 80668 10945 2 1235.625934 618.8202 Magnesium transporter protein 1 OS=Homo sapiens OX=9606 GN=MAGT1 PE=1 SV=1 6.07 2123.3 - 1.20E+06 - - - 0.0688 - 2.547 0.475 - 405 1 2 0 0.0001 10 0 0 0 1.93E+07 2.62E+07 - - - 5.159 0.9998 221125_WJC_METTL3_EV_vs_WT_F06.10946.10946.2 9.05E-07 13/24 R.GLLQTEPQNNQAK.E sp|Q9Y3D6|FIS1_HUMAN 1 1439.7369 1.95 80669 10946 2 1439.735301 720.8757 Mitochondrial fission 1 protein OS=Homo sapiens OX=9606 GN=FIS1 PE=1 SV=2 6 2123.4 - 1.15E+06 - - - -1.0801 - 2.538 0.447 - 497.2 1 2 0 -0.0016 13 0 0 0 9.56E+08 4.91E+08 - - - 4.7325 0.9999 221125_WJC_METTL3_EV_vs_WT_F06.10947.10947.3 2.75E-07 17/60 R.IQPEEK[136.11]PVEVSPAVTK[136.11].G sp|Q8N0X7|SPART_HUMAN 1 1765.9797 1.24 80670 10947 3 1765.977525 589.6672 Spartin OS=Homo sapiens OX=9606 GN=SPART PE=1 SV=1 4.79 2123.5 - 1.08E+06 - - - -1.2124 - 2.687 0.382 - 375.3 1 2 0 -0.0021 16 0 0 0 4.00E+08 3.23E+08 - - - 5.3345 1 221125_WJC_METTL3_EV_vs_WT_F06.10955.10955.3 5.08E-08 15/60 R.IQPEEKPVEVSPAVTK.G sp|Q8N0X7|SPART_HUMAN 1 1749.9513 1.24 80676 10955 3 1749.951375 584.3244 Spartin OS=Homo sapiens OX=9606 GN=SPART PE=1 SV=1 4.79 2124.6 - 2.24E+06 - - - 0.0623 - 2.958 0.582 - 296.7 1 2 0 0.0001 16 0 0 0 4.00E+08 3.23E+08 - - - 7.8114 1 221125_WJC_METTL3_EV_vs_WT_F06.10956.10956.3 2.26E-07 18/64 R.VGMVETNSQDR[166.11]PVDDVK[136.11].L sp|Q9Y3C6|PPIL1_HUMAN 1 1905.9221 1.09 80677 10956 3 1905.924159 636.3146 Peptidyl-prolyl cis-trans isomerase-like 1 OS=Homo sapiens OX=9606 GN=PPIL1 PE=1 SV=1 4.23 2124.6 - 2.17E+06 - - - 1.0745 - 3.29 0.53 - 415.3 1 2 0 0.002 17 0 0 0 8.64E+07 7.94E+07 - - - 7.457 1 221125_WJC_METTL3_EV_vs_WT_F06.10957.10957.3 7.86E-08 19/64 R.VGMVETNSQDRPVDDVK.L sp|Q9Y3C6|PPIL1_HUMAN 1 1887.8996 1.09 80678 10957 3 1887.898873 630.3072 Peptidyl-prolyl cis-trans isomerase-like 1 OS=Homo sapiens OX=9606 GN=PPIL1 PE=1 SV=1 4.23 2124.8 - 1.59E+06 - - - -0.4068 - 3.326 0.585 - 511.3 1 2 0 -0.0008 17 0 0 0 8.64E+07 7.94E+07 - - - 8.098 0.9999 221125_WJC_METTL3_EV_vs_WT_F06.10959.10959.2 2.05E-05 20-Dec R.NFGSYVTHETK[136.11].H "sp|Q96FJ2|DYL2_HUMAN,sp|P63167|DYL1_HUMAN" 2 1289.6132 1.14 80680 10959 2 1289.612836 645.8139 "Dynein light chain 2, cytoplasmic OS=Homo sapiens OX=9606 GN=DYNLL2 PE=1 SV=1" 6.75 2125 - 1.07E+06 - - - -0.2559 - 2.251 0.522 - 417.4 1 2 0 -0.0003 11 0 0 0 7.81E+07 6.83E+07 - - - 5.0913 0.9906 221125_WJC_METTL3_EV_vs_WT_F06.10961.10961.2 0.0127 26-Aug K.QEAVVEEDYNENAK.N "sp|P82970|HMGN5_HUMAN,tr|Q5JSK9|Q5JSK9_HUMAN,tr|Q5JSK8|Q5JSK8_HUMAN,tr|Q5JSK7|Q5JSK7_HUMAN,tr|Q5JSK6|Q5JSK6_HUMAN,tr|Q5JSL0|Q5JSL0_HUMAN" 6 1636.7217 1.89 80682 10961 2 1636.713357 819.3681 High mobility group nucleosome-binding domain-containing protein 5 OS=Homo sapiens OX=9606 GN=HMGN5 PE=1 SV=1 3.91 2125.3 - 374789 - - - -5.0729 - 1.678 0.373 - 91.8 1 2 0 -0.0083 14 0 0 0 4.49E+06 2.37E+06 - - - 3.0923 0.9966 221125_WJC_METTL3_EV_vs_WT_F06.10962.10962.2 0.00407 14/18 R.NKLDHYAIIK.F "sp|P62750|RL23A_HUMAN,tr|H7BY10|H7BY10_HUMAN,tr|K7ERT8|K7ERT8_HUMAN,tr|A8MUS3|A8MUS3_HUMAN,tr|K7EJV9|K7EJV9_HUMAN" 5 1213.6819 0.53 80683 10962 2 1213.682421 607.8482 60S ribosomal protein L23a OS=Homo sapiens OX=9606 GN=RPL23A PE=1 SV=1 8.51 2125.4 - 298845 - - - 0.4227 - 2.053 0.352 - 444.2 1 2 1 0.0005 10 0 0 0 5.92E+06 1.11E+07 - - - 3.6485 0.9999 221125_WJC_METTL3_EV_vs_WT_F06.10968.10968.3 0.00131 Nov-36 K.DHNIPGELER.Q sp|P35580|MYH10_HUMAN 1 1178.568 0.79 80687 10968 3 1178.567033 393.8633 Myosin-10 OS=Homo sapiens OX=9606 GN=MYH10 PE=1 SV=3 4.65 2126.1 - 2.02E+06 - - - -0.8205 - 2.258 0.422 - 252.5 1 2 0 -0.001 10 0 0 0 4.68E+07 5.96E+07 - - - 5.6233 0.9456 221125_WJC_METTL3_EV_vs_WT_F06.10969.10969.3 0.0162 Oct-40 E.YDPTIEDSYR[166.11]K[136.11].Q "sp|P01111|RASN_HUMAN,sp|P01112|RASH_HUMAN,sp|P62834|RAP1A_HUMAN,sp|P61224|RAP1B_HUMAN,sp|P01116|RASK_HUMAN,tr|F5H7Y6|F5H7Y6_HUMAN,tr|A0A804HKM6|A0A804HKM6_HUMAN,tr|F5H500|F5H500_HUMAN,tr|E7ESV4|E7ESV4_HUMAN,tr|F5H491|F5H491_HUMAN,tr|F5GX62|F5GX62_HUMAN,tr|F5H4H0|F5H4H0_HUMAN,tr|F5H6R7|F5H6R7_HUMAN,tr|A0A075B6Q0|A0A075B6Q0_HUMAN,tr|F5H077|F5H077_HUMAN,tr|F5H004|F5H004_HUMAN,tr|A0A804HJ06|A0A804HJ06_HUMAN,tr|F5H0B7|F5H0B7_HUMAN,tr|F5GYB5|F5GYB5_HUMAN,tr|F5GWU8|F5GWU8_HUMAN,tr|F5GYH7|F5GYH7_HUMAN" 21 1403.6688 1.41 80688 10969 3 1403.66757 468.8969 GTPase NRas OS=Homo sapiens OX=9606 GN=NRAS PE=1 SV=1 4.56 2126.1 - 971989 - - - -0.862 - 1.843 0.312 - 86.2 1 1 0 -0.0012 11 0 0 0 2.71E+07 1.92E+07 - - - 3.755 0.9981 221125_WJC_METTL3_EV_vs_WT_F06.10970.10970.2 0.00102 18-Dec R.NK[136.11]LDHYAIIK[136.11].F "sp|P62750|RL23A_HUMAN,tr|H7BY10|H7BY10_HUMAN,tr|K7ERT8|K7ERT8_HUMAN,tr|A8MUS3|A8MUS3_HUMAN,tr|K7EJV9|K7EJV9_HUMAN" 5 1229.7103 0.53 80689 10970 2 1229.710403 615.8624 60S ribosomal protein L23a OS=Homo sapiens OX=9606 GN=RPL23A PE=1 SV=1 8.51 2126.3 - 783291 - - - 0.0773 - 2.511 0.371 - 489 1 2 1 0.0001 10 0 0 0 5.92E+06 1.11E+07 - - - 4.3511 0.9999 221125_WJC_METTL3_EV_vs_WT_F06.10978.10978.3 3.56E-06 14/48 K.FWETDESSKDGPK.G "sp|Q14671|PUM1_HUMAN,tr|Q5T1Z8|Q5T1Z8_HUMAN,tr|H0YEH2|H0YEH2_HUMAN,tr|Q5T1Z4|Q5T1Z4_HUMAN" 4 1524.6733 2.44 80694 10978 3 1524.672231 509.2317 Pumilio homolog 1 OS=Homo sapiens OX=9606 GN=PUM1 PE=1 SV=3 4.32 2127.2 - 1.80E+07 - - - -0.6703 - 2.728 0.577 - 177.5 1 2 1 -0.001 13 0 0 0 3.57E+08 1.46E+08 - - - 7.6937 0.9996 221125_WJC_METTL3_EV_vs_WT_F06.10981.10981.2 6.13E-06 13/24 K.EVSTNTAMIQTSK.T "sp|P13646|K1C13_HUMAN,tr|K7ERE3|K7ERE3_HUMAN" 2 1408.6868 999 80696 10981 2 1408.691153 705.3507 "Keratin, type I cytoskeletal 13 OS=Homo sapiens OX=9606 GN=KRT13 PE=1 SV=4" 6.1 2127.5 - 871599 - - - 3.0937 - 2.478 0.579 - 466.4 1 2 0 0.0044 13 0 0 0 1.24E+07 0.00E+00 - - - 5.6451 0.9999 221125_WJC_METTL3_EV_vs_WT_F06.10989.10989.3 0.00569 Dec-44 R.K[136.11]DPGVPNSAPFK[136.11].E "sp|Q9BVP2|GNL3_HUMAN,tr|C9JYH9|C9JYH9_HUMAN,tr|B4DMU5|B4DMU5_HUMAN,tr|C9JZT7|C9JZT7_HUMAN" 4 1271.6845 0.68 80702 10989 3 1271.68287 424.9021 Guanine nucleotide-binding protein-like 3 OS=Homo sapiens OX=9606 GN=GNL3 PE=1 SV=2 8.59 2128.5 - 3.97E+06 - - - -1.2715 - 2.501 0.409 - 297.6 1 2 0 -0.0016 12 0 0 0 8.80E+07 1.29E+08 - - - 5.6404 1 221125_WJC_METTL3_EV_vs_WT_F06.10990.10990.3 2.30E-05 16/48 K.EVHTQAENAEFMR.N "sp|P09601|HMOX1_HUMAN,tr|B1AHA8|B1AHA8_HUMAN,tr|A0A7I2V3I1|A0A7I2V3I1_HUMAN,tr|A0A7I2V277|A0A7I2V277_HUMAN" 4 1560.6991 1.54 80703 10990 3 1560.697833 521.2403 Heme oxygenase 1 OS=Homo sapiens OX=9606 GN=HMOX1 PE=1 SV=1 4.75 2128.6 - 2.04E+06 - - - -0.806 - 2.93 0.547 - 388 1 2 0 -0.0013 13 0 0 0 4.29E+07 2.79E+07 - - - 7.5528 0.9997 221125_WJC_METTL3_EV_vs_WT_F06.10991.10991.2 9.59E-06 15/18 R.RQLDSIVGER.G "sp|P48668|K2C6C_HUMAN,sp|P13647|K2C5_HUMAN,sp|P02538|K2C6A_HUMAN,tr|F8W0C6|F8W0C6_HUMAN" 4 1171.6309 184.12 80704 10991 2 1171.632504 586.8227 "Keratin, type II cytoskeletal 6C OS=Homo sapiens OX=9606 GN=KRT6C PE=1 SV=3" 6.07 2128.7 - 1.85E+06 - - - 1.3392 - 2.761 0.293 - 419.9 1 2 0 0.0016 10 0 0 0 3.66E+08 1.99E+06 - - - 4.0394 1 221125_WJC_METTL3_EV_vs_WT_F06.10992.10992.3 5.42E-06 16/48 K.EVHTQAENAEFMR[166.11].N "sp|P09601|HMOX1_HUMAN,tr|B1AHA8|B1AHA8_HUMAN,tr|A0A7I2V3I1|A0A7I2V3I1_HUMAN,tr|A0A7I2V277|A0A7I2V277_HUMAN" 4 1570.7074 1.64 80705 10992 3 1570.706828 524.5764 Heme oxygenase 1 OS=Homo sapiens OX=9606 GN=HMOX1 PE=1 SV=1 4.75 2128.8 - 1.79E+06 - - - -0.3393 - 3.015 0.516 - 497.2 1 2 0 -0.0005 13 0 0 0 4.63E+07 2.81E+07 - - - 7.2849 0.9996 221125_WJC_METTL3_EV_vs_WT_F06.10999.10999.3 0.0153 Dec-36 R.RQLDSIVGER.G "sp|P48668|K2C6C_HUMAN,sp|P13647|K2C5_HUMAN,sp|P02538|K2C6A_HUMAN,tr|F8W0C6|F8W0C6_HUMAN" 4 1171.6309 15.59 80710 10999 3 1171.630368 391.5509 "Keratin, type II cytoskeletal 6C OS=Homo sapiens OX=9606 GN=KRT6C PE=1 SV=3" 6.07 2129.8 - 3.63E+06 - - - -0.4839 - 2.292 0.273 - 271.4 1 2 0 -0.0006 10 0 0 0 3.00E+08 1.92E+07 - - - 4.0058 1 221125_WJC_METTL3_EV_vs_WT_F06.11003.11003.3 6.59E-07 16/36 R.HMGLFDHAAR.L "sp|P50213|IDH3A_HUMAN,tr|H0YL72|H0YL72_HUMAN,tr|H0YNF5|H0YNF5_HUMAN" 3 1153.5451 1.17 80714 11003 3 1153.542376 385.5223 "Isocitrate dehydrogenase [NAD] subunit alpha, mitochondrial OS=Homo sapiens OX=9606 GN=IDH3A PE=1 SV=1" 6.92 2130.1 - 1.07E+06 - - - -2.3588 - 2.715 0.521 - 332.9 1 2 0 -0.0027 10 0 0 0 2.02E+07 1.72E+07 - - - 7.2648 0.9999 221125_WJC_METTL3_EV_vs_WT_F06.11006.11006.2 8.97E-06 30-Aug R.IQPEEKPVEVSPAVTK.G sp|Q8N0X7|SPART_HUMAN 1 1749.9513 1.31 80717 11006 2 1749.95142 875.9829 Spartin OS=Homo sapiens OX=9606 GN=SPART PE=1 SV=1 4.79 2130.5 - 605031 - - - 0.088 - 1.9 0.534 - 133.4 1 2 0 0.0002 16 0 0 0 1.48E+07 1.14E+07 - - - 4.5631 0.9995 221125_WJC_METTL3_EV_vs_WT_F06.11007.11007.2 0.000177 30-Nov R.IQPEEK[136.11]PVEVSPAVTK[136.11].G sp|Q8N0X7|SPART_HUMAN 1 1765.9797 1.31 80718 11007 2 1765.97625 883.9971 Spartin OS=Homo sapiens OX=9606 GN=SPART PE=1 SV=1 4.79 2130.7 - 515381 - - - -1.9343 - 2.07 0.413 - 312 1 2 0 -0.0034 16 0 0 0 1.48E+07 1.14E+07 - - - 3.8791 0.9994 221125_WJC_METTL3_EV_vs_WT_F06.11010.11010.3 0.00925 Sep-32 R.AYSWYQHQR[166.11].A "sp|P52848|NDST1_HUMAN,sp|P52849|NDST2_HUMAN,sp|Q9H3R1|NDST4_HUMAN,sp|O95803|NDST3_HUMAN,tr|S4R438|S4R438_HUMAN" 5 1247.5711 1 80721 11010 3 1247.569638 416.8643 Bifunctional heparan sulfate N-deacetylase\N-sulfotransferase 1 OS=Homo sapiens OX=9606 GN=NDST1 PE=1 SV=1 8.64 2131 - 392459 - - - -1.1919 - 1.573 0.347 - 81.5 1 2 0 -0.0015 9 0 0 0 6.28E+06 6.28E+06 - - - 3.7735 0.9997 221125_WJC_METTL3_EV_vs_WT_F06.11011.11011.2 9.75E-05 24-Sep K.GNSSLGMTVSANK.D "sp|O75970|MPDZ_HUMAN,tr|H0YGQ3|H0YGQ3_HUMAN,tr|F5H1U9|F5H1U9_HUMAN" 3 1264.6082 0.2 80722 11011 2 1264.610676 633.3114 Multiple PDZ domain protein OS=Homo sapiens OX=9606 GN=MPDZ PE=1 SV=2 8.75 2131.1 - 385482 - - - 1.9975 - 1.901 0.566 - 293 1 2 0 0.0025 13 0 0 0 4.75E+06 2.33E+07 - - - 4.8694 0.9998 221125_WJC_METTL3_EV_vs_WT_F06.11015.11015.2 0.000684 20-Jul R.NFGSYVTHETK.H "sp|Q96FJ2|DYL2_HUMAN,sp|P63167|DYL1_HUMAN" 2 1281.599 1.17 80725 11015 2 1281.597592 641.8068 "Dynein light chain 2, cytoplasmic OS=Homo sapiens OX=9606 GN=DYNLL2 PE=1 SV=1" 6.75 2131.5 - 4.28E+06 - - - -1.0721 - 1.672 0.531 - 121.5 1 2 0 -0.0014 11 0 0 0 7.81E+07 6.69E+07 - - - 4.3531 1 221125_WJC_METTL3_EV_vs_WT_F06.11017.11017.3 9.08E-08 13/48 K.RPAEDMEEEQAFK.R "sp|P61978|HNRPK_HUMAN,tr|S4R457|S4R457_HUMAN,tr|Q5T6W2|Q5T6W2_HUMAN" 3 1578.6984 1.32 80727 11017 3 1578.695456 527.2401 Heterogeneous nuclear ribonucleoprotein K OS=Homo sapiens OX=9606 GN=HNRNPK PE=1 SV=1 4.25 2131.6 - 1.65E+06 - - - -1.8788 - 2.695 0.56 - 230.5 1 2 0 -0.003 13 0 0 0 1.71E+08 1.30E+08 - - - 7.4706 0.9999 221125_WJC_METTL3_EV_vs_WT_F06.11018.11018.2 0.000187 22-Dec K.QYAGYDYSQQGR.F sp|Q969M3|YIPF5_HUMAN 1 1434.6164 1.32 80728 11018 2 1434.616126 718.3155 Protein YIPF5 OS=Homo sapiens OX=9606 GN=YIPF5 PE=1 SV=1 5.83 2131.7 - 1.16E+06 - - - -0.1959 - 2.313 0.54 - 684.5 1 2 0 -0.0003 12 0 0 0 1.57E+07 1.19E+07 - - - 5.2357 0.9983 221125_WJC_METTL3_EV_vs_WT_F06.11019.11019.3 0.00914 13/36 R.NSSQLTVHLR[166.11].S "sp|Q9NTW7|ZF64B_HUMAN,tr|H0Y669|H0Y669_HUMAN,tr|A2A2N5|A2A2N5_HUMAN" 3 1163.6286 1.59 80729 11019 3 1163.626737 388.8835 Zinc finger protein 64 OS=Homo sapiens OX=9606 GN=ZFP64 PE=1 SV=3 9.76 2131.8 - 1.15E+06 - - - -1.6354 - 2.103 0.22 - 217.1 1 2 0 -0.0019 10 0 0 0 2.42E+07 1.52E+07 - - - 3.1632 1 221125_WJC_METTL3_EV_vs_WT_F06.11021.11021.2 3.43E-08 14/28 K.QIVGTPVNSEDSDTR[166.11].Q "sp|Q5QJE6|TDIF2_HUMAN,tr|J3KP30|J3KP30_HUMAN" 2 1626.7725 1.49 80731 11021 2 1626.769571 814.3935 Deoxynucleotidyltransferase terminal-interacting protein 2 OS=Homo sapiens OX=9606 GN=DNTTIP2 PE=1 SV=2 4.03 2132 - 922787 - - - -1.7778 - 2.622 0.597 - 623.1 1 2 0 -0.0029 15 0 0 0 2.77E+07 1.86E+07 - - - 5.8194 1 221125_WJC_METTL3_EV_vs_WT_F06.11022.11022.2 2.88E-08 14/28 K.QIVGTPVNSEDSDTR.Q "sp|Q5QJE6|TDIF2_HUMAN,tr|J3KP30|J3KP30_HUMAN" 2 1616.7642 1.49 80732 11022 2 1616.765882 809.3894 Deoxynucleotidyltransferase terminal-interacting protein 2 OS=Homo sapiens OX=9606 GN=DNTTIP2 PE=1 SV=2 4.03 2132.2 - 699006 - - - 1.0447 - 2.498 0.607 - 498.1 1 2 0 0.0017 15 0 0 0 2.77E+07 1.86E+07 - - - 5.7745 0.9788 221125_WJC_METTL3_EV_vs_WT_F06.11027.11027.3 0.209 13/60 K.SIGTANR[166.11]PMGAGEALR[166.11].R "sp|Q12906|ILF3_HUMAN,tr|K7EQR9|K7EQR9_HUMAN" 2 1619.8317 1.24 80735 11027 3 1619.832788 540.9512 Interleukin enhancer-binding factor 3 OS=Homo sapiens OX=9606 GN=ILF3 PE=1 SV=3 9.31 2132.8 - 946177 - - - 0.6939 - 1.268 0.198 - 98.3 1 2 0 0.0011 16 0 0 0 9.43E+06 7.62E+06 - - - 1.3564 0.9995 221125_WJC_METTL3_EV_vs_WT_F06.11031.11031.2 0.00213 16-Aug R.DNSEEFLK[136.11]R[166.11].E "sp|Q99700|ATX2_HUMAN,tr|F8W0B5|F8W0B5_HUMAN,tr|A0A5F9ZHW5|A0A5F9ZHW5_HUMAN,tr|A0A5F9ZHH4|A0A5F9ZHH4_HUMAN,tr|A0A5F9ZI57|A0A5F9ZI57_HUMAN,tr|A0A2R8YDM9|A0A2R8YDM9_HUMAN,tr|F8VQP2|F8VQP2_HUMAN,tr|A0A2R8Y5A6|A0A2R8Y5A6_HUMAN,tr|F8WB06|F8WB06_HUMAN,tr|A0A5F9ZH85|A0A5F9ZH85_HUMAN,tr|F8VRK6|F8VRK6_HUMAN,tr|V9GY86|V9GY86_HUMAN,tr|A0A2R8Y7E6|A0A2R8Y7E6_HUMAN,tr|A0A5F9ZHX3|A0A5F9ZHX3_HUMAN,tr|H0YH87|H0YH87_HUMAN,tr|A0A2R8Y7P6|A0A2R8Y7P6_HUMAN" 16 1154.5687 1.15 80739 11031 2 1154.570719 578.2916 Ataxin-2 OS=Homo sapiens OX=9606 GN=ATXN2 PE=1 SV=2 4.68 2133.3 - 609390 - - - 1.773 - 1.977 0.376 - 364.5 1 2 0 0.002 9 0 0 0 1.43E+07 1.24E+07 - - - 3.7893 1 221125_WJC_METTL3_EV_vs_WT_F06.11032.11032.3 5.03E-05 14/36 R.STRPQAWVPR.E "sp|O94880|PHF14_HUMAN,tr|B4DG57|B4DG57_HUMAN,tr|A0A0U1RRH6|A0A0U1RRH6_HUMAN" 3 1196.6414 1.18 80740 11032 3 1196.641452 399.8878 PHD finger protein 14 OS=Homo sapiens OX=9606 GN=PHF14 PE=1 SV=2 12 2133.5 - 534417 - - - 0.01 - 2.776 0.474 - 295 1 2 0 0 10 0 0 0 2.28E+07 1.93E+07 - - - 6.8064 0.9999 221125_WJC_METTL3_EV_vs_WT_F06.11035.11035.2 1.27E-06 14/26 K.GDATVSYEDPPTAK.A "sp|Q01844|EWS_HUMAN,tr|B0QYK0|B0QYK0_HUMAN,tr|H7BY36|H7BY36_HUMAN,tr|A0A0D9SFL3|A0A0D9SFL3_HUMAN,tr|C9JGE3|C9JGE3_HUMAN" 5 1449.6624 0.78 80742 11035 2 1449.662033 725.8385 RNA-binding protein EWS OS=Homo sapiens OX=9606 GN=EWSR1 PE=1 SV=1 4.03 2133.8 - 1.08E+08 - - - -0.2214 - 2.284 0.581 - 402.1 1 2 0 -0.0003 14 0 0 0 1.95E+09 2.50E+09 - - - 5.4048 1 221125_WJC_METTL3_EV_vs_WT_F06.11038.11038.3 9.55E-07 13/52 K.GDATVSYEDPPTAK[136.11].A "sp|Q01844|EWS_HUMAN,tr|B0QYK0|B0QYK0_HUMAN,tr|H7BY36|H7BY36_HUMAN,tr|A0A0D9SFL3|A0A0D9SFL3_HUMAN,tr|C9JGE3|C9JGE3_HUMAN" 5 1457.6766 1.17 80744 11038 3 1457.674305 486.8995 RNA-binding protein EWS OS=Homo sapiens OX=9606 GN=EWSR1 PE=1 SV=1 4.03 2134.1 - 5.01E+06 - - - -1.5429 - 2.253 0.608 - 169.3 1 2 0 -0.0022 14 0 0 0 7.10E+07 6.06E+07 - - - 7.4766 0.9939 221125_WJC_METTL3_EV_vs_WT_F06.11039.11039.3 0.000182 Dec-32 R.DNSEEFLKR.E "sp|Q99700|ATX2_HUMAN,tr|F8W0B5|F8W0B5_HUMAN,tr|A0A5F9ZHW5|A0A5F9ZHW5_HUMAN,tr|A0A5F9ZHH4|A0A5F9ZHH4_HUMAN,tr|A0A5F9ZI57|A0A5F9ZI57_HUMAN,tr|A0A2R8YDM9|A0A2R8YDM9_HUMAN,tr|F8VQP2|F8VQP2_HUMAN,tr|A0A2R8Y5A6|A0A2R8Y5A6_HUMAN,tr|F8WB06|F8WB06_HUMAN,tr|A0A5F9ZH85|A0A5F9ZH85_HUMAN,tr|F8VRK6|F8VRK6_HUMAN,tr|V9GY86|V9GY86_HUMAN,tr|A0A2R8Y7E6|A0A2R8Y7E6_HUMAN,tr|A0A5F9ZHX3|A0A5F9ZHX3_HUMAN,tr|H0YH87|H0YH87_HUMAN,tr|A0A2R8Y7P6|A0A2R8Y7P6_HUMAN" 16 1136.5462 0.03 80745 11039 3 1137.546582 379.856 Ataxin-2 OS=Homo sapiens OX=9606 GN=ATXN2 PE=1 SV=2 4.68 2134.2 - 909729 - - - 880.193 - 2.275 0.424 - 284.3 1 2 0 1.0004 9 0 0 0 1.47E+06 4.86E+07 - - - 5.4674 0.9995 221125_WJC_METTL3_EV_vs_WT_F06.11041.11041.2 0.018 16-Sep R.DNSEEFLKR.E "sp|Q99700|ATX2_HUMAN,tr|F8W0B5|F8W0B5_HUMAN,tr|A0A5F9ZHW5|A0A5F9ZHW5_HUMAN,tr|A0A5F9ZHH4|A0A5F9ZHH4_HUMAN,tr|A0A5F9ZI57|A0A5F9ZI57_HUMAN,tr|A0A2R8YDM9|A0A2R8YDM9_HUMAN,tr|F8VQP2|F8VQP2_HUMAN,tr|A0A2R8Y5A6|A0A2R8Y5A6_HUMAN,tr|F8WB06|F8WB06_HUMAN,tr|A0A5F9ZH85|A0A5F9ZH85_HUMAN,tr|F8VRK6|F8VRK6_HUMAN,tr|V9GY86|V9GY86_HUMAN,tr|A0A2R8Y7E6|A0A2R8Y7E6_HUMAN,tr|A0A5F9ZHX3|A0A5F9ZHX3_HUMAN,tr|H0YH87|H0YH87_HUMAN,tr|A0A2R8Y7P6|A0A2R8Y7P6_HUMAN" 16 1136.5462 0.97 80747 11041 2 1136.543676 569.2804 Ataxin-2 OS=Homo sapiens OX=9606 GN=ATXN2 PE=1 SV=2 4.68 2134.5 - 614867 - - - -2.2225 - 2.085 0.399 - 416.9 1 2 0 -0.0025 9 0 0 0 1.20E+07 1.24E+07 - - - 4.1129 0.9999 221125_WJC_METTL3_EV_vs_WT_F06.11042.11042.2 1.97E-07 13/24 K.RPAEDMEEEQAFK.R "sp|P61978|HNRPK_HUMAN,tr|S4R457|S4R457_HUMAN,tr|Q5T6W2|Q5T6W2_HUMAN" 3 1578.6984 1.39 80748 11042 2 1578.696181 790.3565 Heterogeneous nuclear ribonucleoprotein K OS=Homo sapiens OX=9606 GN=HNRNPK PE=1 SV=1 4.25 2134.6 - 423570 - - - -1.4195 - 2.779 0.548 - 427.4 1 2 0 -0.0022 13 0 0 0 2.70E+07 1.94E+07 - - - 5.7111 1 221125_WJC_METTL3_EV_vs_WT_F06.11048.11048.2 8.08E-10 16/24 V.QALEEANNDLENK.L sp|P35527|K1C9_HUMAN 1 1486.69 999 80752 11048 2 1486.688147 744.3523 "Keratin, type I cytoskeletal 9 OS=Homo sapiens OX=9606 GN=KRT9 PE=1 SV=3" 4 2135.2 - 2.65E+06 - - - -1.2235 - 3.193 0.527 - 1324.5 1 1 0 -0.0018 13 0 0 0 5.79E+07 0.00E+00 - - - 5.9125 0.9986 221125_WJC_METTL3_EV_vs_WT_F06.11054.11054.3 0.00208 Sep-36 K.DVFR[166.11]DPALK[136.11]R[166.11].K "sp|P61353|RL27_HUMAN,tr|K7ELC7|K7ELC7_HUMAN" 2 1243.7031 1.04 80758 11054 3 1243.701989 415.575 60S ribosomal protein L27 OS=Homo sapiens OX=9606 GN=RPL27 PE=1 SV=2 8.75 2135.9 - 763696 - - - -0.9303 - 1.843 0.35 - 164 1 2 1 -0.0012 10 0 0 0 1.67E+08 1.60E+08 - - - 4.2274 0.9997 221125_WJC_METTL3_EV_vs_WT_F06.11060.11060.3 0.106 13/44 K.LDIPTGTTPQRK.S "sp|P52732|KIF11_HUMAN,tr|A0A7I2V3A9|A0A7I2V3A9_HUMAN" 2 1325.7303 4.03 80762 11060 3 1325.728459 442.9174 Kinesin-like protein KIF11 OS=Homo sapiens OX=9606 GN=KIF11 PE=1 SV=2 8.75 2136.6 - 3.14E+06 - - - -1.3992 - 2.403 0.301 - 327.6 1 2 0 -0.0019 12 0 0 0 7.87E+08 1.95E+08 - - - 4.3255 0.9926 221125_WJC_METTL3_EV_vs_WT_F06.11061.11061.3 0.0832 Oct-32 K.KIFEYETQR.R "sp|P50402|EMD_HUMAN,tr|A0A804HLA2|A0A804HLA2_HUMAN,tr|A0A804HIV7|A0A804HIV7_HUMAN" 3 1212.6139 0.63 80763 11061 3 1212.614249 405.2119 Emerin OS=Homo sapiens OX=9606 GN=EMD PE=1 SV=1 6.14 2136.7 - 1.50E+06 - - - 0.2977 - 1.514 0.197 - 150.4 1 2 0 0.0004 9 0 0 0 3.61E+07 5.76E+07 - - - 1.9862 0.9999 221125_WJC_METTL3_EV_vs_WT_F06.11062.11062.3 0.00134 17/44 R.LFGEVTRPTNSK.S "sp|Q9Y291|RT33_HUMAN,tr|C9JBY7|C9JBY7_HUMAN" 2 1347.7147 0.63 80764 11062 3 1347.716191 450.2455 "28S ribosomal protein S33, mitochondrial OS=Homo sapiens OX=9606 GN=MRPS33 PE=1 SV=1" 8.75 2136.8 - 1.64E+06 - - - 1.133 - 2.703 0.405 - 298.8 1 2 0 0.0015 12 0 0 0 3.33E+07 5.25E+07 - - - 5.8112 1 221125_WJC_METTL3_EV_vs_WT_F06.11063.11063.3 3.06E-07 13/60 K.ATAGDTHLGGEDFDNR[166.11].L "sp|P48741|HSP77_HUMAN,sp|P0DMV8|HS71A_HUMAN,sp|P34931|HS71L_HUMAN,sp|P0DMV9|HS71B_HUMAN,sp|P17066|HSP76_HUMAN,tr|Q53FA3|Q53FA3_HUMAN,tr|V9GZ37|V9GZ37_HUMAN,tr|A0A0G2JIW1|A0A0G2JIW1_HUMAN" 8 1684.7317 0.29 80765 11063 3 1684.73203 562.5845 Putative heat shock 70 kDa protein 7 OS=Homo sapiens OX=9606 GN=HSPA7 PE=5 SV=2 4.22 2136.9 - 1.21E+06 - - - 0.219 - 2.755 0.578 - 236.3 1 2 0 0.0004 16 0 0 0 4.07E+06 1.39E+07 - - - 7.5843 0.9999 221125_WJC_METTL3_EV_vs_WT_F06.11064.11064.2 3.60E-06 17/24 K.R[166.11]PAEDMEEEQAFK[136.11].R "sp|P61978|HNRPK_HUMAN,tr|S4R457|S4R457_HUMAN,tr|Q5T6W2|Q5T6W2_HUMAN" 3 1596.7209 1.37 80766 11064 2 1596.71954 799.3677 Heterogeneous nuclear ribonucleoprotein K OS=Homo sapiens OX=9606 GN=HNRNPK PE=1 SV=1 4.25 2137.1 - 1.09E+06 - - - -0.8467 - 2.646 0.531 - 411.2 1 2 0 -0.0014 13 0 0 0 2.70E+07 1.97E+07 - - - 5.4599 0.999 221125_WJC_METTL3_EV_vs_WT_F06.11065.11065.2 1.34E-05 22-Nov R.NNSFTAPSTVGK.R "sp|O95453|PARN_HUMAN,tr|A0A494C0Q6|A0A494C0Q6_HUMAN,tr|A0A494C0W0|A0A494C0W0_HUMAN,tr|A0A494C0K5|A0A494C0K5_HUMAN" 4 1221.599 1.24 80767 11065 2 1221.593826 611.8068 Poly(A)-specific ribonuclease PARN OS=Homo sapiens OX=9606 GN=PARN PE=1 SV=1 8.75 2137.2 - 707033 - - - -4.2076 - 2.539 0.534 - 528.4 1 2 0 -0.0051 12 0 0 0 1.82E+07 1.47E+07 - - - 5.4352 0.8438 221125_WJC_METTL3_EV_vs_WT_F06.11066.11066.2 1.15 20-Jun K.FQK[136.11]GEGK[136.11]DEEK.Y "sp|O75525|KHDR3_HUMAN,tr|E5RJZ9|E5RJZ9_HUMAN,tr|E5RHD3|E5RHD3_HUMAN,tr|E5RG12|E5RG12_HUMAN" 4 1309.6485 - 80768 11066 2 1309.650456 655.8315 "KH domain-containing, RNA-binding, signal transduction-associated protein 3 OS=Homo sapiens OX=9606 GN=KHDRBS3 PE=1 SV=1" 4.87 2137.3 - 672715 - - - 1.4973 - 1.5 0.106 - 81.9 4 2 2 0.002 11 0 0 0 - - - - - 0.6512 0.9998 221125_WJC_METTL3_EV_vs_WT_F06.11069.11069.3 0.00182 Oct-40 K.ADQDR[166.11]LDLEER[166.11].K "sp|Q14683|SMC1A_HUMAN,tr|G8JLG1|G8JLG1_HUMAN,tr|A0A6Q8PHC3|A0A6Q8PHC3_HUMAN" 3 1378.6592 1.52 80769 11069 3 1378.657898 460.5603 Structural maintenance of chromosomes protein 1A OS=Homo sapiens OX=9606 GN=SMC1A PE=1 SV=2 4.11 2137.7 - 5.36E+06 - - - -0.9168 - 2.292 0.441 - 83.8 1 2 1 -0.0013 11 0 0 0 2.73E+08 1.79E+08 - - - 5.8126 0.9992 221125_WJC_METTL3_EV_vs_WT_F06.11072.11072.3 0.033 Dec-44 K.LDIPTGTTPQR[166.11]K[136.11].S "sp|P52732|KIF11_HUMAN,tr|A0A7I2V3A9|A0A7I2V3A9_HUMAN" 2 1343.7528 4.03 80772 11072 3 1343.750811 448.9249 Kinesin-like protein KIF11 OS=Homo sapiens OX=9606 GN=KIF11 PE=1 SV=2 8.75 2138.1 - 2.00E+06 - - - -1.4683 - 2.109 0.275 - 192.1 1 2 0 -0.002 12 0 0 0 7.87E+08 1.95E+08 - - - 3.6738 1 221125_WJC_METTL3_EV_vs_WT_F06.11077.11077.2 9.06E-08 26-Nov K.GDATVSYEDPPTAK[136.11].A "sp|Q01844|EWS_HUMAN,tr|B0QYK0|B0QYK0_HUMAN,tr|H7BY36|H7BY36_HUMAN,tr|A0A0D9SFL3|A0A0D9SFL3_HUMAN,tr|C9JGE3|C9JGE3_HUMAN" 5 1457.6766 0.78 80776 11077 2 1457.675464 729.8456 RNA-binding protein EWS OS=Homo sapiens OX=9606 GN=EWSR1 PE=1 SV=1 4.03 2138.6 - 5.42E+07 - - - -0.7478 - 2.158 0.656 - 187.8 1 2 0 -0.0011 14 0 0 0 1.95E+09 2.50E+09 - - - 5.8161 0.9981 221125_WJC_METTL3_EV_vs_WT_F06.11081.11081.3 1.94E-05 13/44 R.AAEEGK[136.11]DYPFAR[166.11].F "sp|Q9NPF5|DMAP1_HUMAN,tr|Q5TG39|Q5TG39_HUMAN,tr|Q5TG38|Q5TG38_HUMAN,tr|Q5TG40|Q5TG40_HUMAN,tr|Q5TG37|Q5TG37_HUMAN" 5 1370.6586 1.23 80779 11081 3 1370.653202 457.8935 DNA methyltransferase 1-associated protein 1 OS=Homo sapiens OX=9606 GN=DMAP1 PE=1 SV=1 4.68 2139 - 2.81E+06 - - - -3.9018 - 2.023 0.474 - 228.1 1 2 1 -0.0053 12 0 0 0 1.37E+08 1.12E+08 - - - 5.7761 0.9763 221125_WJC_METTL3_EV_vs_WT_F06.11082.11082.3 0.217 Jun-52 K.GDATVSYEDPPTAK.A "sp|Q01844|EWS_HUMAN,tr|B0QYK0|B0QYK0_HUMAN,tr|H7BY36|H7BY36_HUMAN,tr|A0A0D9SFL3|A0A0D9SFL3_HUMAN,tr|C9JGE3|C9JGE3_HUMAN" 5 1449.6624 1.17 80780 11082 3 1449.659977 484.2281 RNA-binding protein EWS OS=Homo sapiens OX=9606 GN=EWSR1 PE=1 SV=1 4.03 2139 - 2.24E+06 - - - -1.6397 - 1.092 0.244 - 32.9 1 2 0 -0.0024 14 0 0 0 7.10E+07 6.06E+07 - - - 1.4936 0.9931 221125_WJC_METTL3_EV_vs_WT_F06.11083.11083.3 0.0302 Jul-32 K.THPQWYPAR[166.11].Q "sp|Q9NZ01|TECR_HUMAN,tr|M0R2N5|M0R2N5_HUMAN,tr|M0R3C3|M0R3C3_HUMAN" 3 1164.5704 2.64 80781 11083 3 1164.568101 389.1974 Very-long-chain enoyl-CoA reductase OS=Homo sapiens OX=9606 GN=TECR PE=1 SV=1 8.44 2139.1 - 539846 - - - -1.9715 - 1.366 0.261 - 79.3 1 2 0 -0.0023 9 0 0 0 4.58E+07 1.74E+07 - - - 2.3892 0.9959 221125_WJC_METTL3_EV_vs_WT_F06.11097.11097.2 2.23 18-Aug R.KFTYLGSQDR.A "sp|Q7Z2W4|ZCCHV_HUMAN,tr|C9J6P4|C9J6P4_HUMAN,tr|A0A7P0T8C6|A0A7P0T8C6_HUMAN" 3 1213.6091 0.92 80789 11097 2 1213.607248 607.8118 Zinc finger CCCH-type antiviral protein 1 OS=Homo sapiens OX=9606 GN=ZC3HAV1 PE=1 SV=3 8.59 2140.7 - 832267 - - - -1.5565 - 1.846 0.134 - 225.7 2 2 0 -0.0019 10 0 0 0 2.39E+07 2.59E+07 - - - 1.6068 1 221125_WJC_METTL3_EV_vs_WT_F06.11106.11106.3 9.20E-07 18/52 K.IGNLAQQGHYDSYK.Q sp|P55771|PAX9_HUMAN 1 1592.7583 2.5 80794 11106 3 1592.755528 531.9267 Paired box protein Pax-9 OS=Homo sapiens OX=9606 GN=PAX9 PE=1 SV=3 6.74 2141.9 - 1.59E+06 - - - -1.7529 - 3.328 0.573 - 587.2 1 2 0 -0.0028 14 0 0 0 3.12E+07 1.25E+07 - - - 8.123 0.8711 221125_WJC_METTL3_EV_vs_WT_F06.11107.11107.3 0.00203 Oct-44 N.IRNEEEVNNLVK.S "sp|Q9BY49|PECR_HUMAN,tr|B4DJS2|B4DJS2_HUMAN" 2 1455.7682 0.37 80795 11107 3 1455.767013 486.2633 Peroxisomal trans-2-enoyl-CoA reductase OS=Homo sapiens OX=9606 GN=PECR PE=1 SV=2 4.79 2142 - 797311 - - - -0.7858 - 2.287 0.303 - 172.9 1 1 1 -0.0011 12 0 0 0 1.93E+07 5.16E+07 - - - 4.2108 0.8599 221125_WJC_METTL3_EV_vs_WT_F06.11108.11108.2 0.00525 26-Nov K.K[136.11]GPGEVAGTVTGQK[136.11].R "sp|Q86U44|MTA70_HUMAN,tr|F5H6D8|F5H6D8_HUMAN,tr|H0YFV6|H0YFV6_HUMAN,tr|B4DTN4|B4DTN4_HUMAN" 4 1343.738 0.001 80796 11108 2 1343.748528 672.8763 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 8.59 2142.1 - 543907 - - - 7.8505 - 1.855 0.205 - 214.3 2 2 0 0.0105 14 0 0 0 0.00E+00 1.27E+07 - - - 1.9679 0.9996 221125_WJC_METTL3_EV_vs_WT_F06.11118.11118.2 6.33E-05 24-Oct R.GLLQTEPQNNQAK[136.11].E sp|Q9Y3D6|FIS1_HUMAN 1 1447.7511 1.95 80802 11118 2 1447.749993 724.8828 Mitochondrial fission 1 protein OS=Homo sapiens OX=9606 GN=FIS1 PE=1 SV=2 6 2143.3 - 4.39E+06 - - - -0.7342 - 1.839 0.388 - 285.7 1 2 0 -0.0011 13 0 0 0 9.56E+08 4.91E+08 - - - 3.47 0.9997 221125_WJC_METTL3_EV_vs_WT_F06.11122.11122.2 0.00054 18-Oct K.DHNIPGELER.Q sp|P35580|MYH10_HUMAN 1 1178.568 1.27 80806 11122 2 1178.565922 590.2913 Myosin-10 OS=Homo sapiens OX=9606 GN=MYH10 PE=1 SV=3 4.65 2143.7 - 850491 - - - -1.7632 - 2.041 0.472 - 466.3 1 2 0 -0.0021 10 0 0 0 2.88E+07 2.26E+07 - - - 4.518 0.9999 221125_WJC_METTL3_EV_vs_WT_F06.11136.11136.2 4.62E-06 22-Dec K.VQSLNIENGSEK.H "sp|Q15643|TRIPB_HUMAN,tr|H0YJ97|H0YJ97_HUMAN" 2 1316.6572 0.99 80816 11136 2 1316.657241 659.3359 Thyroid receptor-interacting protein 11 OS=Homo sapiens OX=9606 GN=TRIP11 PE=1 SV=3 4.53 2145.3 - 1.01E+06 - - - 0.0243 - 2.503 0.477 - 561.7 1 2 0 0 12 0 0 0 2.04E+08 2.05E+08 - - - 4.9782 0.9998 221125_WJC_METTL3_EV_vs_WT_F06.11140.11140.3 2.48E-06 13/52 R.GK[136.11]ATISNDGATILK[136.11].L "sp|Q99832|TCPH_HUMAN,tr|F8WAM2|F8WAM2_HUMAN" 2 1403.7955 0.001 80818 11140 3 1403.793725 468.9391 T-complex protein 1 subunit eta OS=Homo sapiens OX=9606 GN=CCT7 PE=1 SV=2 8.59 2145.9 - 4.08E+06 - - - -1.2602 - 2.539 0.49 - 258.3 1 2 1 -0.0018 14 0 0 0 0.00E+00 6.10E+07 - - - 6.4787 0.9991 221125_WJC_METTL3_EV_vs_WT_F06.11141.11141.3 0.0447 14/44 K.GISVHISNAEPK[136.11].H "sp|Q13148|TADBP_HUMAN,tr|A0A087WX67|A0A087WX67_HUMAN,tr|A0A087WX29|A0A087WX29_HUMAN,tr|G3V162|G3V162_HUMAN,tr|A0A087WV68|A0A087WV68_HUMAN,tr|A0A087WXV3|A0A087WXV3_HUMAN,tr|A0A087WYY0|A0A087WYY0_HUMAN,tr|A0A087WTZ4|A0A087WTZ4_HUMAN,tr|A0A087WW61|A0A087WW61_HUMAN,tr|A0A087WYE7|A0A087WYE7_HUMAN,tr|B1AKP7|B1AKP7_HUMAN,tr|K7EL26|K7EL26_HUMAN,tr|A0A087WZC9|A0A087WZC9_HUMAN,tr|A0A087WXQ5|A0A087WXQ5_HUMAN,tr|A0A087X260|A0A087X260_HUMAN" 15 1258.6761 1.46 80819 11141 3 1258.673955 420.566 TAR DNA-binding protein 43 OS=Homo sapiens OX=9606 GN=TARDBP PE=1 SV=1 6.75 2146 - 2.15E+06 - - - -1.7042 - 2.066 0.283 - 196.9 1 2 0 -0.0021 12 0 0 0 1.71E+09 1.17E+09 - - - 3.7059 0.9997 221125_WJC_METTL3_EV_vs_WT_F06.11142.11142.3 0.0225 14/48 K.LFHTAPNVPHYAK[136.11].N "sp|P53582|MAP11_HUMAN,tr|H0Y955|H0Y955_HUMAN" 2 1501.7921 1.58 80820 11142 3 1501.790962 501.6047 Methionine aminopeptidase 1 OS=Homo sapiens OX=9606 GN=METAP1 PE=1 SV=2 8.61 2146.1 - 1.53E+06 - - - -0.7797 - 2.189 0.326 - 254.7 1 2 0 -0.0012 13 0 0 0 2.52E+07 1.60E+07 - - - 4.2984 0.7721 221125_WJC_METTL3_EV_vs_WT_F06.11143.11143.3 0.00307 Dec-36 K.QR[166.11]YPDGIISK[136.11].P sp|Q86U44|MTA70_HUMAN 1 1193.6523 0.37 80821 11143 3 1193.650372 398.8914 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 8.59 2146.2 - 980133 - - - -1.6504 - 2.017 0.301 - 185.1 1 1 1 -0.002 10 0 0 0 2.04E+07 5.45E+07 - - - 3.9443 0.9475 221125_WJC_METTL3_EV_vs_WT_F06.11146.11146.2 0.00599 20-Jul L.DIPTGTTPQRK.S "sp|P52732|KIF11_HUMAN,tr|A0A7I2V3A9|A0A7I2V3A9_HUMAN" 2 1212.6463 999 80824 11146 2 1212.643872 607.3304 Kinesin-like protein KIF11 OS=Homo sapiens OX=9606 GN=KIF11 PE=1 SV=2 8.75 2146.6 - 617979 - - - -1.961 - 1.545 0.398 - 123.4 1 1 0 -0.0024 11 0 0 0 1.11E+07 0.00E+00 - - - 3.1567 0.9999 221125_WJC_METTL3_EV_vs_WT_F06.11151.11151.2 3.27E-06 22-Nov K.VQSLNIENGSEK[136.11].H "sp|Q15643|TRIPB_HUMAN,tr|H0YJ97|H0YJ97_HUMAN" 2 1324.6714 1.07 80827 11151 2 1324.670145 663.343 Thyroid receptor-interacting protein 11 OS=Homo sapiens OX=9606 GN=TRIP11 PE=1 SV=3 4.53 2147.2 - 3.64E+06 - - - -0.9542 - 2.356 0.531 - 487.4 1 2 0 -0.0013 12 0 0 0 2.02E+08 1.89E+08 - - - 5.2174 1 221125_WJC_METTL3_EV_vs_WT_F06.11152.11152.3 5.20E-08 14/44 R.AAEEGKDYPFAR.F "sp|Q9NPF5|DMAP1_HUMAN,tr|Q5TG39|Q5TG39_HUMAN,tr|Q5TG38|Q5TG38_HUMAN,tr|Q5TG40|Q5TG40_HUMAN,tr|Q5TG37|Q5TG37_HUMAN" 5 1352.6361 1.22 80828 11152 3 1352.636148 451.886 DNA methyltransferase 1-associated protein 1 OS=Homo sapiens OX=9606 GN=DMAP1 PE=1 SV=1 4.68 2147.3 - 2.84E+06 - - - 0.0503 - 2.732 0.619 - 288.2 1 2 1 0.0001 12 0 0 0 1.36E+08 1.12E+08 - - - 8.227 0.9915 221125_WJC_METTL3_EV_vs_WT_F06.11153.11153.2 4.15E-05 18-Nov L.SVHISNAEPK[136.11].H "sp|Q13148|TADBP_HUMAN,tr|A0A087WX67|A0A087WX67_HUMAN,tr|A0A087WX29|A0A087WX29_HUMAN,tr|G3V162|G3V162_HUMAN,tr|A0A087WV68|A0A087WV68_HUMAN,tr|A0A087WXV3|A0A087WXV3_HUMAN,tr|A0A087WYY0|A0A087WYY0_HUMAN,tr|A0A087WTZ4|A0A087WTZ4_HUMAN,tr|A0A087WW61|A0A087WW61_HUMAN,tr|A0A087WYE7|A0A087WYE7_HUMAN,tr|B1AKP7|B1AKP7_HUMAN,tr|K7EL26|K7EL26_HUMAN,tr|A0A087WZC9|A0A087WZC9_HUMAN,tr|A0A087WXQ5|A0A087WXQ5_HUMAN,tr|A0A087X260|A0A087X260_HUMAN" 15 1088.5706 1.53 80829 11153 2 1088.569746 545.2926 TAR DNA-binding protein 43 OS=Homo sapiens OX=9606 GN=TARDBP PE=1 SV=1 6.47 2147.4 - 1.26E+06 - - - -0.7597 - 2.21 0.47 - 380.8 1 1 0 -0.0008 10 0 0 0 3.06E+08 2.00E+08 - - - 4.7256 1 221125_WJC_METTL3_EV_vs_WT_F06.11154.11154.2 0.000841 18/22 K.GISVHISNAEPK[136.11].H "sp|Q13148|TADBP_HUMAN,tr|A0A087WX67|A0A087WX67_HUMAN,tr|A0A087WX29|A0A087WX29_HUMAN,tr|G3V162|G3V162_HUMAN,tr|A0A087WV68|A0A087WV68_HUMAN,tr|A0A087WXV3|A0A087WXV3_HUMAN,tr|A0A087WYY0|A0A087WYY0_HUMAN,tr|A0A087WTZ4|A0A087WTZ4_HUMAN,tr|A0A087WW61|A0A087WW61_HUMAN,tr|A0A087WYE7|A0A087WYE7_HUMAN,tr|B1AKP7|B1AKP7_HUMAN,tr|K7EL26|K7EL26_HUMAN,tr|A0A087WZC9|A0A087WZC9_HUMAN,tr|A0A087WXQ5|A0A087WXQ5_HUMAN,tr|A0A087X260|A0A087X260_HUMAN" 15 1258.6761 1.41 80830 11154 2 1258.674418 630.3453 TAR DNA-binding protein 43 OS=Homo sapiens OX=9606 GN=TARDBP PE=1 SV=1 6.75 2147.5 - 1.26E+06 - - - -1.3363 - 3.262 0.535 - 1020 1 2 0 -0.0017 12 0 0 0 3.51E+08 2.49E+08 - - - 6.1029 0.9998 221125_WJC_METTL3_EV_vs_WT_F06.11155.11155.2 6.03E-05 14/26 R.GAPANVSSSDLTGR.Q "sp|P49674|KC1E_HUMAN,tr|H0Y5S9|H0Y5S9_HUMAN,tr|H0Y682|H0Y682_HUMAN" 3 1330.6477 0.95 80831 11155 2 1330.647033 666.3311 Casein kinase I isoform epsilon OS=Homo sapiens OX=9606 GN=CSNK1E PE=1 SV=1 5.84 2147.6 - 650884 - - - -0.5065 - 1.958 0.433 - 402.3 1 2 0 -0.0007 14 0 0 0 3.63E+07 3.82E+07 - - - 3.9251 0.9996 221125_WJC_METTL3_EV_vs_WT_F06.11159.11159.3 0.0185 13/52 K.VDEAVAVLQAHHAK[136.11].K "sp|Q13310|PABP4_HUMAN,tr|A0A7I2V5W9|A0A7I2V5W9_HUMAN,tr|H0YEU6|H0YEU6_HUMAN,tr|B1ANR0|B1ANR0_HUMAN,tr|A0A7I2V4L7|A0A7I2V4L7_HUMAN,tr|H0YER0|H0YER0_HUMAN,tr|A0A7I2V598|A0A7I2V598_HUMAN,tr|A0A7I2V4V6|A0A7I2V4V6_HUMAN,tr|H0Y5F5|H0Y5F5_HUMAN,tr|H0Y6X6|H0Y6X6_HUMAN" 10 1494.8034 1.45 80833 11159 3 1494.800615 499.2751 Polyadenylate-binding protein 4 OS=Homo sapiens OX=9606 GN=PABPC4 PE=1 SV=1 5.99 2148.2 - 2.17E+06 - - - -1.8805 - 2.29 0.337 - 255.9 1 2 0 -0.0028 14 0 0 0 9.05E+07 6.23E+07 - - - 4.4983 1 221125_WJC_METTL3_EV_vs_WT_F06.11160.11160.3 8.70E-08 20/52 K.VINQYQVVK[136.11]PTAER[166.11].T sp|Q14694|UBP10_HUMAN 1 1661.922 0.94 80834 11160 3 1661.91887 554.9813 Ubiquitin carboxyl-terminal hydrolase 10 OS=Homo sapiens OX=9606 GN=USP10 PE=1 SV=2 8.56 2148.3 - 1.34E+06 - - - -1.8683 - 2.818 0.525 - 525.5 1 2 0 -0.0031 14 0 0 0 4.49E+07 4.78E+07 - - - 7.1456 1 221125_WJC_METTL3_EV_vs_WT_F06.11161.11161.3 4.23E-08 17/52 K.VDEAVAVLQAHHAK.K "sp|Q13310|PABP4_HUMAN,tr|A0A7I2V5W9|A0A7I2V5W9_HUMAN,tr|H0YEU6|H0YEU6_HUMAN,tr|B1ANR0|B1ANR0_HUMAN,tr|A0A7I2V4L7|A0A7I2V4L7_HUMAN,tr|H0YER0|H0YER0_HUMAN,tr|A0A7I2V598|A0A7I2V598_HUMAN,tr|A0A7I2V4V6|A0A7I2V4V6_HUMAN,tr|H0Y5F5|H0Y5F5_HUMAN,tr|H0Y6X6|H0Y6X6_HUMAN" 10 1486.7892 1.45 80835 11161 3 1486.787781 496.6037 Polyadenylate-binding protein 4 OS=Homo sapiens OX=9606 GN=PABPC4 PE=1 SV=1 5.99 2148.4 - 2.64E+06 - - - -0.9719 - 3.199 0.489 - 553 1 2 0 -0.0014 14 0 0 0 9.05E+07 6.26E+07 - - - 7.0817 0.9283 221125_WJC_METTL3_EV_vs_WT_F06.11164.11164.3 0.162 Jun-44 K.GISVHISNAEPK.H "sp|Q13148|TADBP_HUMAN,tr|A0A087WX67|A0A087WX67_HUMAN,tr|A0A087WX29|A0A087WX29_HUMAN,tr|G3V162|G3V162_HUMAN,tr|A0A087WV68|A0A087WV68_HUMAN,tr|A0A087WXV3|A0A087WXV3_HUMAN,tr|A0A087WYY0|A0A087WYY0_HUMAN,tr|A0A087WTZ4|A0A087WTZ4_HUMAN,tr|A0A087WW61|A0A087WW61_HUMAN,tr|A0A087WYE7|A0A087WYE7_HUMAN,tr|B1AKP7|B1AKP7_HUMAN,tr|K7EL26|K7EL26_HUMAN,tr|A0A087WZC9|A0A087WZC9_HUMAN,tr|A0A087WXQ5|A0A087WXQ5_HUMAN,tr|A0A087X260|A0A087X260_HUMAN" 15 1250.6619 1.46 80836 11164 3 1250.659657 417.8946 TAR DNA-binding protein 43 OS=Homo sapiens OX=9606 GN=TARDBP PE=1 SV=1 6.75 2148.8 - 3.42E+07 - - - -1.7935 - 1.243 0.157 - 33.9 1 2 0 -0.0022 12 0 0 0 1.71E+09 1.18E+09 - - - 0.8927 0.9999 221125_WJC_METTL3_EV_vs_WT_F06.11165.11165.3 2.45E-05 17/52 K.VINQYQVVKPTAER.T sp|Q14694|UBP10_HUMAN 1 1643.8995 0.94 80837 11165 3 1643.895235 548.9738 Ubiquitin carboxyl-terminal hydrolase 10 OS=Homo sapiens OX=9606 GN=USP10 PE=1 SV=2 8.56 2148.9 - 1.50E+06 - - - -2.5975 - 2.719 0.462 - 339.4 1 2 0 -0.0043 14 0 0 0 4.49E+07 4.78E+07 - - - 6.3479 1 221125_WJC_METTL3_EV_vs_WT_F06.11171.11171.2 1.09E-08 17/36 R.EAAAYSSGGGAAGAGLAGR.E "sp|P43694|GATA4_HUMAN,tr|A0A087WZ09|A0A087WZ09_HUMAN" 2 1592.7543 2.65 80841 11171 2 1592.753294 797.3844 Transcription factor GATA-4 OS=Homo sapiens OX=9606 GN=GATA4 PE=1 SV=2 6.1 2149.7 - 1.48E+06 - - - -0.6297 - 3.725 0.678 - 721.9 1 2 0 -0.001 19 0 0 0 3.94E+07 1.48E+07 - - - 7.2815 0.9998 221125_WJC_METTL3_EV_vs_WT_F06.11172.11172.2 0.000599 22-Nov K.GISVHISNAEPK.H "sp|Q13148|TADBP_HUMAN,tr|A0A087WX67|A0A087WX67_HUMAN,tr|A0A087WX29|A0A087WX29_HUMAN,tr|G3V162|G3V162_HUMAN,tr|A0A087WV68|A0A087WV68_HUMAN,tr|A0A087WXV3|A0A087WXV3_HUMAN,tr|A0A087WYY0|A0A087WYY0_HUMAN,tr|A0A087WTZ4|A0A087WTZ4_HUMAN,tr|A0A087WW61|A0A087WW61_HUMAN,tr|A0A087WYE7|A0A087WYE7_HUMAN,tr|B1AKP7|B1AKP7_HUMAN,tr|K7EL26|K7EL26_HUMAN,tr|A0A087WZC9|A0A087WZC9_HUMAN,tr|A0A087WXQ5|A0A087WXQ5_HUMAN,tr|A0A087X260|A0A087X260_HUMAN" 15 1250.6619 1.41 80842 11172 2 1250.660674 626.3382 TAR DNA-binding protein 43 OS=Homo sapiens OX=9606 GN=TARDBP PE=1 SV=1 6.75 2149.7 - 9.57E+06 - - - -0.9803 - 2.083 0.48 - 267.5 1 2 0 -0.0012 12 0 0 0 3.51E+08 2.49E+08 - - - 4.5167 0.9996 221125_WJC_METTL3_EV_vs_WT_F06.11173.11173.3 0.00072 13/36 K.AK[136.11]DPFAHLPK[136.11].S sp|P26641|EF1G_HUMAN 1 1138.647 0.001 80843 11173 3 1138.644429 380.5563 Elongation factor 1-gamma OS=Homo sapiens OX=9606 GN=EEF1G PE=1 SV=3 8.64 2149.8 - 967009 - - - -2.2395 - 2.441 0.45 - 158.8 1 2 1 -0.0026 10 0 0 0 0.00E+00 9.77E+07 - - - 6.1626 0.9989 221125_WJC_METTL3_EV_vs_WT_F06.11174.11174.2 0.0178 20-Sep R.DLTLEENQVK[136.11]K[136.11].Y "sp|Q14683|SMC1A_HUMAN,tr|G8JLG1|G8JLG1_HUMAN" 2 1331.7267 1.02 80844 11174 2 1331.725313 666.8706 Structural maintenance of chromosomes protein 1A OS=Homo sapiens OX=9606 GN=SMC1A PE=1 SV=2 4.68 2150 - 782780 - - - -1.076 - 1.542 0.304 - 249.1 1 2 0 -0.0014 11 0 0 0 1.43E+07 1.40E+07 - - - 2.4575 0.9994 221125_WJC_METTL3_EV_vs_WT_F06.11175.11175.2 0.0139 22-Nov K.K[136.11]VESTGAVPEFK[136.11].E sp|Q6YN16|HSDL2_HUMAN 1 1306.7104 0.36 80845 11175 2 1306.711377 654.3625 Hydroxysteroid dehydrogenase-like protein 2 OS=Homo sapiens OX=9606 GN=HSDL2 PE=1 SV=1 6.14 2150.1 - 517942 - - - 0.7729 - 1.875 0.306 - 317.1 1 2 0 0.001 12 0 0 0 5.76E+06 1.61E+07 - - - 2.9548 1 221125_WJC_METTL3_EV_vs_WT_F06.11181.11181.2 7.33E-08 18/36 R.EAAAYSSGGGAAGAGLAGR[166.11].E "sp|P43694|GATA4_HUMAN,tr|A0A087WZ09|A0A087WZ09_HUMAN" 2 1602.7626 2.65 80849 11181 2 1602.756305 802.3886 Transcription factor GATA-4 OS=Homo sapiens OX=9606 GN=GATA4 PE=1 SV=2 6.1 2150.8 - 1.02E+06 - - - -3.907 - 3.462 0.686 - 925.1 1 2 0 -0.0063 19 0 0 0 3.94E+07 1.48E+07 - - - 7.159 0.9766 221125_WJC_METTL3_EV_vs_WT_F06.11185.11185.3 0.0535 Oct-36 K.QQASHYLYVR[166.11].A sp|Q9Y3A4|RRP7A_HUMAN 1 1273.6443 1.17 80851 11185 3 1273.640879 425.5554 Ribosomal RNA-processing protein 7 homolog A OS=Homo sapiens OX=9606 GN=RRP7A PE=1 SV=2 8.6 2151.3 - 2.20E+06 - - - -2.6781 - 1.569 0.187 - 176.7 1 2 0 -0.0034 10 0 0 0 2.76E+07 2.36E+07 - - - 1.9394 0.9891 221125_WJC_METTL3_EV_vs_WT_F06.11198.11198.3 0.26 Dec-40 R.DLTLEENQVK[136.11]K[136.11].Y "sp|Q14683|SMC1A_HUMAN,tr|G8JLG1|G8JLG1_HUMAN" 2 1331.7267 0.95 80860 11198 3 1331.724361 444.9162 Structural maintenance of chromosomes protein 1A OS=Homo sapiens OX=9606 GN=SMC1A PE=1 SV=2 4.68 2152.7 - 3.33E+06 - - - -1.7909 - 1.736 0.172 - 147.3 1 2 0 -0.0024 11 0 0 0 6.48E+07 6.85E+07 - - - 2.0239 0.999 221125_WJC_METTL3_EV_vs_WT_F06.11204.11204.2 0.031 22-Sep K.SIDSFGQVSHPK[136.11].N sp|Q86XZ4|SPAS2_HUMAN 1 1308.6554 0.75 80866 11204 2 1308.657594 655.335 Spermatogenesis-associated serine-rich protein 2 OS=Homo sapiens OX=9606 GN=SPATS2 PE=1 SV=1 6.46 2153.5 - 806332 - - - 1.7033 - 1.792 0.326 - 229.4 1 2 0 0.0022 12 0 0 0 8.15E+06 1.09E+07 - - - 2.983 0.9895 221125_WJC_METTL3_EV_vs_WT_F06.11205.11205.3 0.0439 Jul-40 K.DFQSGQHVIVR.T "sp|P46459|NSF_HUMAN,tr|I3L4Q9|I3L4Q9_HUMAN,tr|I3L338|I3L338_HUMAN,tr|I3L0L3|I3L0L3_HUMAN,tr|I3L0N3|I3L0N3_HUMAN" 5 1284.6575 3.65 80867 11205 3 1284.655034 429.2264 Vesicle-fusing ATPase OS=Homo sapiens OX=9606 GN=NSF PE=1 SV=3 6.74 2153.6 - 798558 - - - -1.9071 - 1.693 0.205 - 64.1 3 2 0 -0.0024 11 0 0 0 1.14E+07 3.12E+06 - - - 2.0998 0.9998 221125_WJC_METTL3_EV_vs_WT_F06.11209.11209.2 5.24E-05 26-Nov K.TQTVTISDNANAVK.S "sp|P11171|EPB41_HUMAN,tr|A0A3B3ITP0|A0A3B3ITP0_HUMAN,tr|A0A2U3TZH6|A0A2U3TZH6_HUMAN,tr|A0A2R8Y7Y3|A0A2R8Y7Y3_HUMAN,tr|A0A2R8YD30|A0A2R8YD30_HUMAN,tr|A0A2R8Y783|A0A2R8Y783_HUMAN" 6 1460.7471 0.88 80869 11209 2 1460.746802 731.3808 Protein 4.1 OS=Homo sapiens OX=9606 GN=EPB41 PE=1 SV=4 5.5 2154.2 - 1.39E+06 - - - -0.1951 - 2.267 0.416 - 305 1 2 0 -0.0003 14 0 0 0 2.52E+07 2.87E+07 - - - 4.1674 1 221125_WJC_METTL3_EV_vs_WT_F06.11214.11214.2 4.77E-11 15/24 R.DGGSGNSTIIVSR[166.11].S sp|Q7Z6Z7|HUWE1_HUMAN 1 1271.6345 0.61 80874 11214 2 1271.631934 636.8245 E3 ubiquitin-protein ligase HUWE1 OS=Homo sapiens OX=9606 GN=HUWE1 PE=1 SV=3 5.84 2154.7 - 788197 - - - -2.0281 - 3.091 0.653 - 1323.6 1 2 0 -0.0026 13 0 0 0 1.74E+07 2.83E+07 - - - 6.7596 0.9992 221125_WJC_METTL3_EV_vs_WT_F06.11219.11219.3 0.00496 13/40 K.GVVEVTHDLQK.H "sp|P50454|SERPH_HUMAN,tr|E9PKH2|E9PKH2_HUMAN,tr|E9PJH8|E9PJH8_HUMAN" 3 1223.651 2.05 80877 11219 3 1223.648259 408.8909 Serpin H1 OS=Homo sapiens OX=9606 GN=SERPINH1 PE=1 SV=2 5.32 2155.4 - 1.45E+06 - - - -2.2408 - 2.159 0.3 - 162.6 1 2 0 -0.0027 11 0 0 0 3.34E+07 1.63E+07 - - - 4.0704 0.9999 221125_WJC_METTL3_EV_vs_WT_F06.11220.11220.3 0.00458 19/56 K.EAVAPVQEESDLEKK.R "sp|Q13409|DC1I2_HUMAN,tr|E7EUM4|E7EUM4_HUMAN,tr|E7ET01|E7ET01_HUMAN,tr|E7ERR6|E7ERR6_HUMAN,tr|E7ETL8|E7ETL8_HUMAN,tr|E7EV09|E7EV09_HUMAN,tr|E9PGG1|E9PGG1_HUMAN,tr|E7ESD3|E7ESD3_HUMAN,tr|E7ERH4|E7ERH4_HUMAN,tr|E7EQU2|E7EQU2_HUMAN,tr|E7EQL5|E7EQL5_HUMAN,tr|E7EU01|E7EU01_HUMAN,tr|E7EMU4|E7EMU4_HUMAN" 13 1670.8363 0.48 80878 11220 3 1670.834972 557.9527 Cytoplasmic dynein 1 intermediate chain 2 OS=Homo sapiens OX=9606 GN=DYNC1I2 PE=1 SV=3 4.25 2155.5 - 1.22E+06 - - - -0.7924 - 2.573 0.423 - 473.9 1 2 0 -0.0013 15 0 0 0 1.02E+07 2.13E+07 - - - 5.7217 1 221125_WJC_METTL3_EV_vs_WT_F06.11221.11221.2 3.77E-09 15/24 K.GQNPNATFGEVSK.L "sp|O94900|TOX_HUMAN,sp|O94842|TOX4_HUMAN,sp|O15405|TOX3_HUMAN" 3 1347.6419 2.25 80879 11221 2 1347.645774 674.8282 Thymocyte selection-associated high mobility group box protein TOX OS=Homo sapiens OX=9606 GN=TOX PE=1 SV=3 6 2155.7 - 827179 - - - 2.8798 - 3.041 0.677 - 812.8 1 2 0 0.0039 13 0 0 0 4.39E+07 1.95E+07 - - - 6.8946 0.9861 221125_WJC_METTL3_EV_vs_WT_F06.11222.11222.2 0.00577 18-Sep K.AK[136.11]DPFAHLPK[136.11].S sp|P26641|EF1G_HUMAN 1 1138.647 0.8 80880 11222 2 1138.644396 570.3308 Elongation factor 1-gamma OS=Homo sapiens OX=9606 GN=EEF1G PE=1 SV=3 8.64 2155.8 - 654640 - - - -2.2685 - 1.566 0.375 - 151.8 1 2 1 -0.0026 10 0 0 0 6.91E+06 8.59E+06 - - - 3.0619 0.801 221125_WJC_METTL3_EV_vs_WT_F06.11229.11229.3 0.184 Sep-40 K.GVVEVTHDLQK[136.11].H "sp|P50454|SERPH_HUMAN,tr|E9PKH2|E9PKH2_HUMAN,tr|E9PJH8|E9PJH8_HUMAN" 3 1231.6652 2.04 80885 11229 3 1231.664638 411.5623 Serpin H1 OS=Homo sapiens OX=9606 GN=SERPINH1 PE=1 SV=2 5.32 2156.5 - 1.12E+06 - - - -0.4571 - 1.538 0.035 - 67.3 2 2 0 -0.0006 11 0 0 0 3.32E+07 1.63E+07 - - - 0.0137 0.999 221125_WJC_METTL3_EV_vs_WT_F06.11231.11231.2 1.00E-06 14/26 R.GAPANVSSSDLTGR[166.11].Q "sp|P49674|KC1E_HUMAN,tr|H0Y5S9|H0Y5S9_HUMAN,tr|H0Y682|H0Y682_HUMAN" 3 1340.656 1.51 80887 11231 2 1340.651063 671.3353 Casein kinase I isoform epsilon OS=Homo sapiens OX=9606 GN=CSNK1E PE=1 SV=1 5.84 2156.8 - 731703 - - - -3.6654 - 2.364 0.466 - 600.6 1 2 0 -0.0049 14 0 0 0 3.44E+07 2.28E+07 - - - 4.6404 0.9998 221125_WJC_METTL3_EV_vs_WT_F06.11233.11233.2 0.00021 14/20 K.GVVEVTHDLQK.H "sp|P50454|SERPH_HUMAN,tr|E9PKH2|E9PKH2_HUMAN,tr|E9PJH8|E9PJH8_HUMAN" 3 1223.651 2.8 80889 11233 2 1223.64944 612.8328 Serpin H1 OS=Homo sapiens OX=9606 GN=SERPINH1 PE=1 SV=2 5.32 2157.1 - 656507 - - - -1.2757 - 2.509 0.411 - 650.8 1 2 0 -0.0016 11 0 0 0 1.42E+07 5.08E+06 - - - 4.5647 0.9978 221125_WJC_METTL3_EV_vs_WT_F06.11245.11245.3 0.037 Dec-36 K.GK[136.11]DMVVDIQR[166.11].R sp|Q9Y266|NUDC_HUMAN 1 1177.6244 1.64 80897 11245 3 1177.62241 393.5487 Nuclear migration protein nudC OS=Homo sapiens OX=9606 GN=NUDC PE=1 SV=1 5.96 2158.5 - 1.96E+06 - - - -1.7009 - 2.062 0.316 - 333.5 1 2 1 -0.002 10 0 0 0 5.09E+07 3.10E+07 - - - 4.176 1 221125_WJC_METTL3_EV_vs_WT_F06.11248.11248.2 2.97E-12 16/24 R.DGGSGNSTIIVSR.S sp|Q7Z6Z7|HUWE1_HUMAN 1 1261.6262 0.61 80900 11248 2 1261.624826 631.8204 E3 ubiquitin-protein ligase HUWE1 OS=Homo sapiens OX=9606 GN=HUWE1 PE=1 SV=3 5.84 2158.8 - 1.96E+06 - - - -1.1232 - 3.204 0.659 - 1472.3 1 2 0 -0.0014 13 0 0 0 1.74E+07 2.83E+07 - - - 6.8964 0.9985 221125_WJC_METTL3_EV_vs_WT_F06.11251.11251.2 0.011 13/20 K.GVVEVTHDLQK[136.11].H "sp|P50454|SERPH_HUMAN,tr|E9PKH2|E9PKH2_HUMAN,tr|E9PJH8|E9PJH8_HUMAN" 3 1231.6652 2.8 80903 11251 2 1231.66166 616.8399 Serpin H1 OS=Homo sapiens OX=9606 GN=SERPINH1 PE=1 SV=2 5.32 2159.2 - 745177 - - - -2.875 - 2.083 0.315 - 466.2 1 2 0 -0.0035 11 0 0 0 1.42E+07 5.08E+06 - - - 3.3516 1 221125_WJC_METTL3_EV_vs_WT_F06.11257.11257.2 2.96E-10 19/32 R.ATGGGLSSVGGGSSTIK.Y sp|P04259|K2C6B_HUMAN 1 1434.7314 840.13 80907 11257 2 1434.730046 718.373 "Keratin, type II cytoskeletal 6B OS=Homo sapiens OX=9606 GN=KRT6B PE=1 SV=5" 8.8 2160 - 1.37E+07 - - - -0.9695 - 3.561 0.61 - 939.7 1 2 0 -0.0014 17 0 0 0 3.70E+09 4.40E+06 - - - 6.6685 0.9987 221125_WJC_METTL3_EV_vs_WT_F06.11263.11263.2 0.000183 18-Nov K.GKDMVVDIQR.R sp|Q9Y266|NUDC_HUMAN 1 1159.6019 2.46 80913 11263 2 1159.60103 580.8082 Nuclear migration protein nudC OS=Homo sapiens OX=9606 GN=NUDC PE=1 SV=1 5.96 2160.6 - 717668 - - - -0.7873 - 2.312 0.497 - 495.4 1 2 1 -0.0009 10 0 0 0 1.59E+07 6.46E+06 - - - 5.051 0.9986 221125_WJC_METTL3_EV_vs_WT_F06.11265.11265.2 8.03E-06 18-Oct K.GK[136.11]DMVVDIQR[166.11].R sp|Q9Y266|NUDC_HUMAN 1 1177.6244 2.46 80915 11265 2 1177.624525 589.8195 Nuclear migration protein nudC OS=Homo sapiens OX=9606 GN=NUDC PE=1 SV=1 5.96 2160.9 - 690326 - - - 0.0951 - 2.005 0.519 - 370.3 1 2 1 0.0001 10 0 0 0 1.59E+07 6.46E+06 - - - 4.8161 0.9998 221125_WJC_METTL3_EV_vs_WT_F06.11267.11267.2 4.81E-06 14/26 K.TQTVTISDNANAVK[136.11].S "sp|P11171|EPB41_HUMAN,tr|A0A3B3ITP0|A0A3B3ITP0_HUMAN,tr|A0A2U3TZH6|A0A2U3TZH6_HUMAN,tr|A0A2R8Y7Y3|A0A2R8Y7Y3_HUMAN,tr|A0A2R8YD30|A0A2R8YD30_HUMAN,tr|A0A2R8Y783|A0A2R8Y783_HUMAN" 6 1468.7613 0.88 80916 11267 2 1468.764414 735.3879 Protein 4.1 OS=Homo sapiens OX=9606 GN=EPB41 PE=1 SV=4 5.5 2161.2 - 542842 - - - 2.129 - 2.526 0.526 - 596.6 1 2 0 0.0031 14 0 0 0 2.52E+07 2.87E+07 - - - 5.2504 0.9999 221125_WJC_METTL3_EV_vs_WT_F06.11269.11269.3 6.29E-07 15/48 K.ASLENSLEETKGR.Y "sp|P02533|K1C14_HUMAN,sp|P08779|K1C16_HUMAN,tr|K7ENW6|K7ENW6_HUMAN" 3 1432.7158 1445.19 80917 11269 3 1432.713306 478.5792 "Keratin, type I cytoskeletal 14 OS=Homo sapiens OX=9606 GN=KRT14 PE=1 SV=4" 4.79 2161.4 - 1.28E+07 - - - -1.7317 - 3.036 0.496 - 422.3 1 2 1 -0.0025 13 0 0 0 1.68E+09 1.16E+06 - - - 7.0802 0.8348 221125_WJC_METTL3_EV_vs_WT_F06.11273.11273.2 0.186 20-Sep T.IDSGELDIGRR.A sp|Q9P273|TEN3_HUMAN 1 1229.6364 0.09 80921 11273 2 1229.638291 615.8255 Teneurin-3 OS=Homo sapiens OX=9606 GN=TENM3 PE=1 SV=3 4.56 2161.7 - 1.72E+06 - - - 1.5265 - 1.526 0.224 - 135.7 1 1 0 0.0019 11 0 0 0 1.64E+07 1.83E+08 - - - 1.8382 0.9985 221125_WJC_METTL3_EV_vs_WT_F06.11275.11275.2 7.67E-05 15/28 K.IK[136.11]VAEDEAEAAAAAK[136.11].F "sp|P08195|4F2_HUMAN,tr|F5H867|F5H867_HUMAN,tr|A0A7P0TAN7|A0A7P0TAN7_HUMAN,tr|J3KPF3|J3KPF3_HUMAN,tr|F5H0E2|F5H0E2_HUMAN,tr|H0YH36|H0YH36_HUMAN,tr|A0A7P0TAT7|A0A7P0TAT7_HUMAN,tr|H0YFS2|H0YFS2_HUMAN,tr|A0A7P0T8U7|A0A7P0T8U7_HUMAN,tr|A0A7P0T9F7|A0A7P0T9F7_HUMAN,tr|A0A7P0TBF8|A0A7P0TBF8_HUMAN,tr|A0A7P0T8F1|A0A7P0T8F1_HUMAN,tr|A0A7P0Z4A0|A0A7P0Z4A0_HUMAN,tr|F5GZS6|F5GZS6_HUMAN,tr|A0A7P0Z4P5|A0A7P0Z4P5_HUMAN,tr|A0A7P0T853|A0A7P0T853_HUMAN,tr|A0A7P0TAS6|A0A7P0TAS6_HUMAN" 17 1501.7959 1.89 80923 11275 2 1501.795259 751.9052 4F2 cell-surface antigen heavy chain OS=Homo sapiens OX=9606 GN=SLC3A2 PE=1 SV=3 4.41 2161.9 - 883405 - - - -0.4188 - 2.247 0.499 - 341.4 1 2 1 -0.0006 15 0 0 0 2.61E+07 1.38E+07 - - - 4.7168 0.9995 221125_WJC_METTL3_EV_vs_WT_F06.11283.11283.3 0.0117 Sep-48 K.NPSDSAVHSPFTK[136.11].R "sp|Q14157|UBP2L_HUMAN,tr|F8W726|F8W726_HUMAN" 2 1393.6717 2.89 80930 11283 3 1393.671268 465.5645 Ubiquitin-associated protein 2-like OS=Homo sapiens OX=9606 GN=UBAP2L PE=1 SV=2 6.74 2162.5 - 7.36E+06 - - - -0.3408 - 1.789 0.332 - 107.5 1 2 0 -0.0005 13 0 0 0 2.16E+08 7.48E+07 - - - 3.8184 0.9936 221125_WJC_METTL3_EV_vs_WT_F06.11284.11284.3 3.33E-08 14/48 Q.EFC[160.03]DYGTK[136.11]EEC[160.03]MK[136.11].A "sp|Q86U44|MTA70_HUMAN,tr|H0YFV6|H0YFV6_HUMAN" 2 1711.6863 0.001 80931 11284 3 1711.684456 571.5694 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 4.41 2162.6 - 3.00E+06 - - - -1.0656 - 2.843 0.574 - 260 1 1 1 -0.0018 13 0 0 0 0.00E+00 6.22E+07 - - - 7.7719 1 221125_WJC_METTL3_EV_vs_WT_F06.11285.11285.2 5.61E-06 17/28 K.IKVAEDEAEAAAAAK.F "sp|P08195|4F2_HUMAN,tr|F5H867|F5H867_HUMAN,tr|A0A7P0TAN7|A0A7P0TAN7_HUMAN,tr|J3KPF3|J3KPF3_HUMAN,tr|F5H0E2|F5H0E2_HUMAN,tr|H0YH36|H0YH36_HUMAN,tr|A0A7P0TAT7|A0A7P0TAT7_HUMAN,tr|H0YFS2|H0YFS2_HUMAN,tr|A0A7P0T8U7|A0A7P0T8U7_HUMAN,tr|A0A7P0T9F7|A0A7P0T9F7_HUMAN,tr|A0A7P0TBF8|A0A7P0TBF8_HUMAN,tr|A0A7P0T8F1|A0A7P0T8F1_HUMAN,tr|A0A7P0Z4A0|A0A7P0Z4A0_HUMAN,tr|F5GZS6|F5GZS6_HUMAN,tr|A0A7P0Z4P5|A0A7P0Z4P5_HUMAN,tr|A0A7P0T853|A0A7P0T853_HUMAN,tr|A0A7P0TAS6|A0A7P0TAS6_HUMAN" 17 1485.7675 1.89 80932 11285 2 1485.764276 743.891 4F2 cell-surface antigen heavy chain OS=Homo sapiens OX=9606 GN=SLC3A2 PE=1 SV=3 4.41 2162.8 - 1.22E+06 - - - -2.1618 - 3.429 0.626 - 561.6 1 2 1 -0.0032 15 0 0 0 2.61E+07 1.38E+07 - - - 6.6932 0.999 221125_WJC_METTL3_EV_vs_WT_F06.11289.11289.3 0.0287 Sep-48 R.LESGMQNMSIHTK.T sp|P05787|K2C8_HUMAN 1 1474.6908 3.07 80934 11289 3 1474.687811 492.5709 "Keratin, type II cytoskeletal 8 OS=Homo sapiens OX=9606 GN=KRT8 PE=1 SV=7" 6.75 2163.3 - 2.17E+06 - - - -2.0499 - 1.805 0.328 - 108.5 1 2 0 -0.003 13 0 0 0 6.93E+07 2.26E+07 - - - 3.7972 1 221125_WJC_METTL3_EV_vs_WT_F06.11290.11290.3 1.12E-09 24/76 K.IVAERPGTNSTGPAPMAPPR.A "sp|Q13263|TIF1B_HUMAN,tr|M0R0K9|M0R0K9_HUMAN" 2 2018.0367 0.35 80935 11290 3 2018.036411 673.6862 Transcription intermediary factor 1-beta OS=Homo sapiens OX=9606 GN=TRIM28 PE=1 SV=5 9.6 2163.4 - 1.57E+06 - - - -0.165 - 3.748 0.631 - 592.5 1 2 0 -0.0003 20 0 0 0 8.65E+07 2.47E+08 - - - 8.7803 1 221125_WJC_METTL3_EV_vs_WT_F06.11293.11293.2 6.14E-05 15/18 R.K[136.11]GEFETGFEK[136.11].G "sp|Q8IYD1|ERF3B_HUMAN,sp|P15170|ERF3A_HUMAN,tr|H3BR35|H3BR35_HUMAN" 3 1186.5841 0.9 80938 11293 2 1186.580723 594.2993 Eukaryotic peptide chain release factor GTP-binding subunit ERF3B OS=Homo sapiens OX=9606 GN=GSPT2 PE=1 SV=2 4.79 2163.7 - 1.25E+06 - - - -2.8494 - 2.983 0.539 - 614.9 1 2 0 -0.0034 10 0 0 0 1.31E+07 1.46E+07 - - - 6.0717 1 221125_WJC_METTL3_EV_vs_WT_F06.11294.11294.3 5.12E-07 20/40 K.TPVEPEVAIHR.L "sp|P60866|RS20_HUMAN,tr|E5RJX2|E5RJX2_HUMAN,tr|E5RIP1|E5RIP1_HUMAN,tr|A0A7P0S5H5|A0A7P0S5H5_HUMAN" 4 1246.667 1.29 80939 11294 3 1246.666245 416.5629 40S ribosomal protein S20 OS=Homo sapiens OX=9606 GN=RPS20 PE=1 SV=1 5.37 2163.9 - 1.01E+06 - - - -0.5944 - 3.755 0.464 - 1113.6 1 2 0 -0.0007 11 0 0 0 1.34E+08 1.04E+08 - - - 7.4716 0.9696 221125_WJC_METTL3_EV_vs_WT_F06.11295.11295.2 7.86E-07 14/26 M.STLPVEDEESSESR[166.11].M "sp|P78347|GTF2I_HUMAN,tr|C9J6M0|C9J6M0_HUMAN,tr|A0A494C1K3|A0A494C1K3_HUMAN" 3 1573.6983 1.64 80940 11295 2 1573.695249 787.8564 General transcription factor II-I OS=Homo sapiens OX=9606 GN=GTF2I PE=1 SV=2 3.91 2164 - 976715 - - - -1.9356 - 2.137 0.384 - 562.1 1 1 0 -0.003 14 0 0 0 9.26E+07 5.65E+07 - - - 3.782 1 221125_WJC_METTL3_EV_vs_WT_F06.11300.11300.2 1.30E-08 14/26 M.STLPVEDEESSESR.M "sp|P78347|GTF2I_HUMAN,tr|C9J6M0|C9J6M0_HUMAN,tr|A0A494C1K3|A0A494C1K3_HUMAN" 3 1563.69 1.64 80943 11300 2 1563.689174 782.8523 General transcription factor II-I OS=Homo sapiens OX=9606 GN=GTF2I PE=1 SV=2 3.91 2164.6 - 1.91E+06 - - - -0.5442 - 2.302 0.684 - 645.5 1 1 0 -0.0009 14 0 0 0 9.26E+07 5.65E+07 - - - 6.1851 0.9977 221125_WJC_METTL3_EV_vs_WT_F06.11302.11302.3 0.0629 13/40 K.QEQVKIESLAK.S "sp|Q16891|MIC60_HUMAN,tr|B9A067|B9A067_HUMAN,tr|A0A087WYS0|A0A087WYS0_HUMAN,tr|C9J406|C9J406_HUMAN" 4 1271.7085 1.23 80945 11302 3 1271.709292 424.9101 MICOS complex subunit MIC60 OS=Homo sapiens OX=9606 GN=IMMT PE=1 SV=1 6.14 2164.8 - 1.04E+06 - - - 0.6102 - 2.106 0.284 - 212.9 1 2 1 0.0008 11 0 0 0 2.92E+07 2.38E+07 - - - 3.8219 0.8722 221125_WJC_METTL3_EV_vs_WT_F06.11304.11304.2 0.345 18-Nov L.ENSLEETKGR.Y "sp|P02533|K1C14_HUMAN,sp|P08779|K1C16_HUMAN,tr|K7ENW6|K7ENW6_HUMAN" 3 1161.5626 999 80947 11304 2 1161.563052 581.7886 "Keratin, type I cytoskeletal 14 OS=Homo sapiens OX=9606 GN=KRT14 PE=1 SV=4" 4.79 2165.1 - 799330 - - - 0.4063 - 2.232 0.375 - 628.2 1 1 1 0.0005 10 0 0 0 1.80E+07 0.00E+00 - - - 4.0517 0.7869 221125_WJC_METTL3_EV_vs_WT_F06.11305.11305.2 0.00167 20-Oct T.YSC[160.03]VGVFQHGK[136.11].V "sp|P54652|HSP72_HUMAN,sp|P0DMV8|HS71A_HUMAN,sp|P34931|HS71L_HUMAN,sp|P11142|HSP7C_HUMAN,sp|P0DMV9|HS71B_HUMAN,tr|E9PQQ4|E9PQQ4_HUMAN,tr|E9PNE6|E9PNE6_HUMAN,tr|E9PKE3|E9PKE3_HUMAN,tr|E9PLF4|E9PLF4_HUMAN,tr|Q53FA3|Q53FA3_HUMAN,tr|E9PI65|E9PI65_HUMAN,tr|V9GZ37|V9GZ37_HUMAN,tr|E9PK54|E9PK54_HUMAN,tr|E9PN25|E9PN25_HUMAN,tr|E9PPY6|E9PPY6_HUMAN,tr|E9PQK7|E9PQK7_HUMAN,tr|A0A0G2JIW1|A0A0G2JIW1_HUMAN" 17 1288.6114 12.67 80948 11305 2 1288.616148 645.313 Heat shock-related 70 kDa protein 2 OS=Homo sapiens OX=9606 GN=HSPA2 PE=1 SV=1 8.21 2165.2 - 598145 - - - 3.6908 - 1.432 0.385 - 284 1 1 0 0.0048 11 0 0 0 6.96E+07 5.49E+06 - - - 2.8545 0.9998 221125_WJC_METTL3_EV_vs_WT_F06.11312.11312.3 0.000221 14/36 R.KGEFETGFEK.G "sp|Q8IYD1|ERF3B_HUMAN,sp|P15170|ERF3A_HUMAN,tr|H3BR35|H3BR35_HUMAN" 3 1170.5557 0.54 80953 11312 3 1170.553787 391.1925 Eukaryotic peptide chain release factor GTP-binding subunit ERF3B OS=Homo sapiens OX=9606 GN=GSPT2 PE=1 SV=2 4.79 2166.1 - 594284 - - - -1.6377 - 2.044 0.396 - 248.2 1 2 0 -0.0019 10 0 0 0 8.35E+06 1.55E+07 - - - 5.0423 1 221125_WJC_METTL3_EV_vs_WT_F06.11316.11316.3 0.000112 14/52 K.YSNSALGHVNC[160.03]TIK[136.11].E "sp|Q9NQC3|RTN4_HUMAN,tr|A0A0U1RQR6|A0A0U1RQR6_HUMAN,tr|F8W914|F8W914_HUMAN,tr|H7C106|H7C106_HUMAN" 4 1570.7653 0.87 80955 11316 3 1570.766364 524.5957 Reticulon-4 OS=Homo sapiens OX=9606 GN=RTN4 PE=1 SV=2 8.21 2166.6 - 1.54E+06 - - - 0.6602 - 2.517 0.45 - 105 1 2 0 0.001 14 0 0 0 3.36E+07 3.87E+07 - - - 6.0099 0.999 221125_WJC_METTL3_EV_vs_WT_F06.11317.11317.3 0.000154 Dec-40 R.K[136.11]GTGLLSSDYR[166.11].L "sp|Q7Z2W4|ZCCHV_HUMAN,tr|C9J6P4|C9J6P4_HUMAN,tr|A0A7P0T8C6|A0A7P0T8C6_HUMAN" 3 1213.6422 0.23 80956 11317 3 1213.637942 405.5547 Zinc finger CCCH-type antiviral protein 1 OS=Homo sapiens OX=9606 GN=ZC3HAV1 PE=1 SV=3 8.59 2166.8 - 632652 - - - -3.4846 - 2.106 0.358 - 189.9 1 2 0 -0.0042 11 0 0 0 3.07E+06 1.32E+07 - - - 4.646 1 221125_WJC_METTL3_EV_vs_WT_F06.11322.11322.2 5.75E-12 20/32 F.GGGAGGGDGGILTANEK.S sp|P35527|K1C9_HUMAN 1 1429.6797 17.04 80959 11322 2 1429.678467 715.8471 "Keratin, type I cytoskeletal 9 OS=Homo sapiens OX=9606 GN=KRT9 PE=1 SV=3" 4.37 2167.4 - 7.17E+06 - - - -0.8869 - 3.956 0.693 - 1419 1 1 0 -0.0013 17 0 0 0 1.74E+08 1.02E+07 - - - 7.5402 1 221125_WJC_METTL3_EV_vs_WT_F06.11331.11331.3 4.28E-07 20/64 K.GLNGQKPPGATEPITVK.F "sp|Q12926|ELAV2_HUMAN,tr|C9JB16|C9JB16_HUMAN,tr|A0A0A0MRX1|A0A0A0MRX1_HUMAN" 3 1705.9363 1.36 80965 11331 3 1705.937979 569.6527 ELAV-like protein 2 OS=Homo sapiens OX=9606 GN=ELAVL2 PE=1 SV=2 8.59 2168.5 - 1.57E+06 - - - 0.993 - 3.528 0.549 - 328.1 1 2 0 0.0017 17 0 0 0 4.17E+07 3.06E+07 - - - 7.8453 0.9883 221125_WJC_METTL3_EV_vs_WT_F06.11332.11332.3 0.18 Sep-40 K.GSQGPLPFHEK[136.11].V "sp|Q9UBX3|DIC_HUMAN,tr|F6RGN5|F6RGN5_HUMAN,tr|I3L1E8|I3L1E8_HUMAN,tr|B4DLN1|B4DLN1_HUMAN" 4 1203.6128 0.66 80966 11332 3 1203.610345 402.2115 Mitochondrial dicarboxylate carrier OS=Homo sapiens OX=9606 GN=SLC25A10 PE=1 SV=2 6.75 2168.7 - 790327 - - - -2.0164 - 1.583 0.2 - 117 1 2 0 -0.0024 11 0 0 0 1.86E+07 2.81E+07 - - - 2.074 0.9731 221125_WJC_METTL3_EV_vs_WT_F06.11336.11336.2 0.000428 30-Sep R.ETGGAEGTGDAVLGEK[136.11].V "sp|Q92667|AKAP1_HUMAN,tr|I3L0W0|I3L0W0_HUMAN" 2 1497.7038 1.05 80970 11336 2 1497.691359 749.8592 "A-kinase anchor protein 1, mitochondrial OS=Homo sapiens OX=9606 GN=AKAP1 PE=1 SV=1" 4 2169.1 - 713684 - - - -8.3274 - 1.85 0.488 - 122.4 1 2 0 -0.0125 16 0 0 0 1.02E+07 9.73E+06 - - - 4.1539 0.9826 221125_WJC_METTL3_EV_vs_WT_F06.11338.11338.3 0.11 Nov-40 K.GSQGPLPFHEK.V "sp|Q9UBX3|DIC_HUMAN,tr|F6RGN5|F6RGN5_HUMAN,tr|I3L1E8|I3L1E8_HUMAN,tr|B4DLN1|B4DLN1_HUMAN" 4 1195.5986 0.62 80972 11338 3 1195.602862 399.5401 Mitochondrial dicarboxylate carrier OS=Homo sapiens OX=9606 GN=SLC25A10 PE=1 SV=2 6.75 2169.4 - 497639 - - - 3.5882 - 1.801 0.211 - 112.4 1 2 0 0.0043 11 0 0 0 1.62E+07 2.64E+07 - - - 2.5626 1 221125_WJC_METTL3_EV_vs_WT_F06.11341.11341.3 9.09E-08 22/76 K.IVAER[166.11]PGTNSTGPAPMAPPR[166.11].A "sp|Q13263|TIF1B_HUMAN,tr|M0R0K9|M0R0K9_HUMAN" 2 2038.0533 0.35 80973 11341 3 2038.052365 680.3584 Transcription intermediary factor 1-beta OS=Homo sapiens OX=9606 GN=TRIM28 PE=1 SV=5 9.6 2169.7 - 3.35E+06 - - - -0.4509 - 3.674 0.622 - 549.9 1 2 0 -0.0009 20 0 0 0 8.65E+07 2.46E+08 - - - 8.6314 0.9999 221125_WJC_METTL3_EV_vs_WT_F06.11342.11342.2 7.31E-10 14/26 K.NLETSSAFQSSSQK.L sp|Q9Y2X9|ZN281_HUMAN 1 1512.7056 1.35 80974 11342 2 1512.703228 757.3601 Zinc finger protein 281 OS=Homo sapiens OX=9606 GN=ZNF281 PE=1 SV=1 6 2169.9 - 1.71E+06 - - - -1.5786 - 2.736 0.534 - 557.8 1 2 0 -0.0024 14 0 0 0 8.13E+07 6.03E+07 - - - 5.5101 1 221125_WJC_METTL3_EV_vs_WT_F06.11344.11344.2 7.95E-07 15/26 K.NLETSSAFQSSSQK[136.11].L sp|Q9Y2X9|ZN281_HUMAN 1 1520.7198 1.36 80976 11344 2 1520.721136 761.3672 Zinc finger protein 281 OS=Homo sapiens OX=9606 GN=ZNF281 PE=1 SV=1 6 2170.1 - 1.34E+06 - - - 0.868 - 3.037 0.58 - 653.7 1 2 0 0.0013 14 0 0 0 8.13E+07 6.00E+07 - - - 6.1121 0.9999 221125_WJC_METTL3_EV_vs_WT_F06.11350.11350.3 1.47E-06 13/40 R.SRNTDEMVELR.L "sp|P61978|HNRPK_HUMAN,tr|S4R457|S4R457_HUMAN,tr|Q5T6W2|Q5T6W2_HUMAN" 3 1348.6405 1.16 80980 11350 3 1348.638646 450.5541 Heterogeneous nuclear ribonucleoprotein K OS=Homo sapiens OX=9606 GN=HNRNPK PE=1 SV=1 4.68 2170.8 - 2.99E+06 - - - -1.3844 - 2.696 0.49 - 448.7 1 2 1 -0.0019 11 0 0 0 1.46E+08 1.26E+08 - - - 6.8199 1 221125_WJC_METTL3_EV_vs_WT_F06.11351.11351.2 5.34E-10 15/30 R.AGAANSQLSTSQPSLR[166.11].H "sp|Q96C57|CSTOS_HUMAN,tr|G5EA44|G5EA44_HUMAN,tr|F5H7W8|F5H7W8_HUMAN" 3 1596.8095 0.81 80981 11351 2 1596.804789 799.412 Protein CUSTOS OS=Homo sapiens OX=9606 GN=CUSTOS PE=1 SV=2 9.79 2170.9 - 840216 - - - -2.9615 - 3.16 0.629 - 714.6 1 2 0 -0.0047 16 0 0 0 1.04E+07 1.28E+07 - - - 6.514 1 221125_WJC_METTL3_EV_vs_WT_F06.11352.11352.3 2.83E-09 22/60 K.SAAMLGNSEDHTALSR.A sp|O60749|SNX2_HUMAN 1 1658.7682 0.88 80982 11352 3 1658.768915 553.93 Sorting nexin-2 OS=Homo sapiens OX=9606 GN=SNX2 PE=1 SV=2 5.3 2171 - 1.57E+06 - - - 0.4111 - 4.536 0.596 - 837 1 2 0 0.0007 16 0 0 0 1.85E+07 2.09E+07 - - - 9.0643 0.9999 221125_WJC_METTL3_EV_vs_WT_F06.11353.11353.3 3.13E-07 18/48 K.NDFTEEEEAQVR[166.11]K[136.11].E "sp|P63208|SKP1_HUMAN,tr|E5RJR5|E5RJR5_HUMAN" 2 1611.7495 0.46 80983 11353 3 1611.743811 538.2571 S-phase kinase-associated protein 1 OS=Homo sapiens OX=9606 GN=SKP1 PE=1 SV=2 4.25 2171.1 - 1.33E+06 - - - -3.5607 - 3.124 0.576 - 501 1 2 0 -0.0057 13 0 0 0 1.52E+07 3.33E+07 - - - 8.0487 0.9999 221125_WJC_METTL3_EV_vs_WT_F06.11357.11357.3 3.52E-07 Nov-44 K.C[160.03]YSC[160.03]GEFGHIQK[136.11].D sp|P62633|CNBP_HUMAN 1 1492.6319 3.41 80985 11357 3 1492.626068 498.5512 CCHC-type zinc finger nucleic acid binding protein OS=Homo sapiens OX=9606 GN=CNBP PE=1 SV=1 6.73 2171.7 - 7.56E+06 - - - -3.8871 - 1.894 0.626 - 143.9 1 2 0 -0.0058 12 0 0 0 5.08E+08 1.49E+08 - - - 7.288 0.9999 221125_WJC_METTL3_EV_vs_WT_F06.11360.11360.3 2.00E-06 13/52 K.NLETSSAFQSSSQK.L sp|Q9Y2X9|ZN281_HUMAN 1 1512.7056 1.41 80988 11360 3 1512.708502 505.2425 Zinc finger protein 281 OS=Homo sapiens OX=9606 GN=ZNF281 PE=1 SV=1 6 2172 - 822291 - - - 1.9078 - 2.459 0.479 - 139.7 1 2 0 0.0029 14 0 0 0 2.21E+07 1.57E+07 - - - 6.2707 0.9893 221125_WJC_METTL3_EV_vs_WT_F06.11365.11365.3 0.00246 Sep-48 K.SEEQLKEEGIEYK.V "sp|P09622|DLDH_HUMAN,tr|E9PEX6|E9PEX6_HUMAN" 2 1580.757 1.29 80991 11365 3 1580.756179 527.9263 "Dihydrolipoyl dehydrogenase, mitochondrial OS=Homo sapiens OX=9606 GN=DLD PE=1 SV=2" 4.32 2172.6 - 3.67E+06 - - - -0.5086 - 1.696 0.247 - 74.1 1 2 1 -0.0008 13 0 0 0 7.50E+07 5.81E+07 - - - 2.7259 1 221125_WJC_METTL3_EV_vs_WT_F06.11366.11366.3 6.22E-09 16/52 K.IEQLQNHENEDIYK.L "sp|O00629|IMA3_HUMAN,tr|A0A7I2YQ95|A0A7I2YQ95_HUMAN,tr|H7C4F6|H7C4F6_HUMAN,tr|A0A7I2V340|A0A7I2V340_HUMAN" 4 1771.8377 1.64 80992 11366 3 1771.837388 591.6198 Importin subunit alpha-3 OS=Homo sapiens OX=9606 GN=KPNA4 PE=1 SV=1 4.4 2172.8 - 2.02E+06 - - - -0.1721 - 3.17 0.461 - 292.7 1 2 0 -0.0003 14 0 0 0 3.97E+07 2.42E+07 - - - 6.7457 0.9627 221125_WJC_METTL3_EV_vs_WT_F06.11368.11368.3 0.00296 Oct-48 R.RLLEGEDAHLSSQ.Q sp|P08779|K1C16_HUMAN 1 1453.7161 34.52 80994 11368 3 1453.719767 485.5793 "Keratin, type I cytoskeletal 16 OS=Homo sapiens OX=9606 GN=KRT16 PE=1 SV=4" 4.65 2172.9 - 968876 - - - 2.5081 - 2.083 0.393 - 113.5 1 1 0 0.0036 13 0 0 0 1.77E+07 5.14E+05 - - - 4.9101 0.9997 221125_WJC_METTL3_EV_vs_WT_F06.11371.11371.2 0.00662 20-Nov K.TPVEPEVAIHR.L "sp|P60866|RS20_HUMAN,tr|E5RJX2|E5RJX2_HUMAN,tr|E5RIP1|E5RIP1_HUMAN,tr|A0A7P0S5H5|A0A7P0S5H5_HUMAN" 4 1246.667 1.24 80997 11371 2 1246.66833 624.3408 40S ribosomal protein S20 OS=Homo sapiens OX=9606 GN=RPS20 PE=1 SV=1 5.37 2173.3 - 650214 - - - 1.0781 - 2.086 0.406 - 440 1 2 0 0.0013 11 0 0 0 9.17E+06 7.41E+06 - - - 4.0283 1 221125_WJC_METTL3_EV_vs_WT_F06.11372.11372.2 3.94E-05 13/34 R.ASPAAPADGAAPAQPSIR.Y sp|Q9P1Y5|CAMP3_HUMAN 1 1646.8376 2.1 80998 11372 2 1646.838029 824.4261 Calmodulin-regulated spectrin-associated protein 3 OS=Homo sapiens OX=9606 GN=CAMSAP3 PE=1 SV=2 5.88 2173.4 - 435273 - - - 0.2405 - 2.547 0.595 - 370.2 1 2 0 0.0004 18 0 0 0 9.81E+06 4.67E+06 - - - 5.7341 1 221125_WJC_METTL3_EV_vs_WT_F06.11376.11376.3 1.93E-07 13/44 K.C[160.03]YSC[160.03]GEFGHIQK.D sp|P62633|CNBP_HUMAN 1 1484.6177 3.41 81000 11376 3 1484.617854 495.8798 CCHC-type zinc finger nucleic acid binding protein OS=Homo sapiens OX=9606 GN=CNBP PE=1 SV=1 6.73 2173.8 - 3.60E+06 - - - 0.1239 - 1.996 0.597 - 243.5 1 2 0 0.0002 12 0 0 0 5.09E+08 1.49E+08 - - - 7.1117 1 221125_WJC_METTL3_EV_vs_WT_F06.11377.11377.3 4.75E-08 18/52 K.IEQLQNHENEDIYK[136.11].L "sp|O00629|IMA3_HUMAN,tr|A0A7I2YQ95|A0A7I2YQ95_HUMAN,tr|H7C4F6|H7C4F6_HUMAN,tr|A0A7I2V340|A0A7I2V340_HUMAN" 4 1779.8519 1.84 81001 11377 3 1779.851017 594.2912 Importin subunit alpha-3 OS=Homo sapiens OX=9606 GN=KPNA4 PE=1 SV=1 4.4 2173.9 - 2.20E+06 - - - -0.4922 - 2.953 0.505 - 419.5 1 2 0 -0.0009 14 0 0 0 4.45E+07 2.42E+07 - - - 7.0476 1 221125_WJC_METTL3_EV_vs_WT_F06.11378.11378.3 9.55E-06 15/60 K.LPSRPGAQGVEPQNLR.T "sp|Q8WXI9|P66B_HUMAN,tr|A0A0U1RRM1|A0A0U1RRM1_HUMAN" 2 1717.9224 1.99 81002 11378 3 1717.922627 573.6481 Transcriptional repressor p66-beta OS=Homo sapiens OX=9606 GN=GATAD2B PE=1 SV=1 9.6 2174 - 1.75E+06 - - - 0.1519 - 3.415 0.467 - 196.3 1 2 0 0.0003 16 0 0 0 1.31E+09 6.58E+08 - - - 6.8979 0.9966 221125_WJC_METTL3_EV_vs_WT_F06.11383.11383.2 1.86E-05 24-Sep R.DSQDAGGFGPEDR.L "sp|Q15149|PLEC_HUMAN,tr|H0YDN1|H0YDN1_HUMAN" 2 1349.5484 2.34 81007 11383 2 1349.551582 675.7815 Plectin OS=Homo sapiens OX=9606 GN=PLEC PE=1 SV=3 3.84 2174.6 - 1.41E+06 - - - 2.3675 - 1.63 0.263 - 118 1 2 0 0.0032 13 0 0 0 1.58E+07 6.75E+06 - - - 2.2365 1 221125_WJC_METTL3_EV_vs_WT_F06.11385.11385.3 4.00E-06 20/68 R.AALAHSEEVTASQVAATK[136.11].T "sp|Q15149|PLEC_HUMAN,tr|H0YDN1|H0YDN1_HUMAN" 2 1790.9254 1.45 81009 11385 3 1790.92578 597.9824 Plectin OS=Homo sapiens OX=9606 GN=PLEC PE=1 SV=3 5.4 2174.8 - 381273 - - - 0.2166 - 3.461 0.581 - 615.6 1 2 0 0.0004 18 0 0 0 3.21E+07 2.21E+07 - - - 8.1091 0.9953 221125_WJC_METTL3_EV_vs_WT_F06.11386.11386.2 0.0209 20-May K.VNWATTPSSQK.K "sp|Q01085|TIAR_HUMAN,sp|P31483|TIA1_HUMAN,tr|F8W8I6|F8W8I6_HUMAN,tr|C9JTN7|C9JTN7_HUMAN,tr|E7ETC0|E7ETC0_HUMAN,tr|H7BY49|H7BY49_HUMAN,tr|A6NKZ9|A6NKZ9_HUMAN,tr|E5RG67|E5RG67_HUMAN,tr|E7ETJ9|E7ETJ9_HUMAN,tr|E5RGV5|E5RGV5_HUMAN" 10 1217.6041 2.23 81010 11386 2 1217.605159 609.8093 Nucleolysin TIAR OS=Homo sapiens OX=9606 GN=TIAL1 PE=1 SV=1 8.72 2175 - 249153 - - - 0.91 - 1.253 0.244 - 58.5 2 2 0 0.0011 11 0 0 0 1.10E+07 4.95E+06 - - - 1.3185 1 221125_WJC_METTL3_EV_vs_WT_F06.11391.11391.3 3.96E-06 22/60 K.LPSR[166.11]PGAQGVEPQNLR[166.11].T "sp|Q8WXI9|P66B_HUMAN,tr|A0A0U1RRM1|A0A0U1RRM1_HUMAN" 2 1737.9389 1.99 81013 11391 3 1737.938408 580.3202 Transcriptional repressor p66-beta OS=Homo sapiens OX=9606 GN=GATAD2B PE=1 SV=1 9.6 2175.5 - 2.66E+06 - - - -0.2865 - 3.711 0.503 - 541.9 1 2 0 -0.0005 16 0 0 0 1.31E+09 6.58E+08 - - - 7.5124 1 221125_WJC_METTL3_EV_vs_WT_F06.11392.11392.2 3.42E-10 19/34 R.PVSSAASVYAGAGGSGSR.L "sp|P05783|K1C18_HUMAN,tr|F8VZY9|F8VZY9_HUMAN" 2 1579.759 2.81 81014 11392 2 1579.75731 790.8868 "Keratin, type I cytoskeletal 18 OS=Homo sapiens OX=9606 GN=KRT18 PE=1 SV=2" 9.18 2175.6 - 1.21E+06 - - - -1.1002 - 3.728 0.648 - 906 1 1 0 -0.0017 18 0 0 0 1.69E+07 6.01E+06 - - - 7.0617 0.9935 221125_WJC_METTL3_EV_vs_WT_F06.11393.11393.3 0.123 Nov-52 K.NLETSSAFQSSSQK[136.11].L sp|Q9Y2X9|ZN281_HUMAN 1 1520.7198 1.47 81015 11393 3 1520.71724 507.9139 Zinc finger protein 281 OS=Homo sapiens OX=9606 GN=ZNF281 PE=1 SV=1 6 2175.7 - 1.04E+06 - - - -1.6939 - 1.786 0.2 - 93.5 1 2 0 -0.0026 14 0 0 0 2.20E+07 1.49E+07 - - - 2.3104 0.9973 221125_WJC_METTL3_EV_vs_WT_F06.11395.11395.2 0.521 22-Dec R.IQNAGGSVMIQR.V "sp|O75688|PPM1B_HUMAN,sp|P35813|PPM1A_HUMAN,tr|B8ZZF0|B8ZZF0_HUMAN,tr|A0A3B3IS24|A0A3B3IS24_HUMAN,tr|C9JIR6|C9JIR6_HUMAN,tr|E9PKB5|E9PKB5_HUMAN" 6 1272.6609 2.99 81017 11395 2 1272.66443 637.3377 Protein phosphatase 1B OS=Homo sapiens OX=9606 GN=PPM1B PE=1 SV=1 9.75 2175.9 - 943986 - - - 2.8091 - 2.373 0.191 - 365.6 1 2 0 0.0036 12 0 0 0 5.06E+06 1.69E+06 - - - 2.7243 1 221125_WJC_METTL3_EV_vs_WT_F06.11397.11397.2 1.06E-07 17/34 R.PVSSAASVYAGAGGSGSR[166.11].L "sp|P05783|K1C18_HUMAN,tr|F8VZY9|F8VZY9_HUMAN" 2 1589.7673 2.81 81019 11397 2 1589.764008 795.8909 "Keratin, type I cytoskeletal 18 OS=Homo sapiens OX=9606 GN=KRT18 PE=1 SV=2" 9.18 2176.2 - 409389 - - - -2.0821 - 3.75 0.665 - 666.9 1 1 0 -0.0033 18 0 0 0 1.69E+07 6.01E+06 - - - 7.2012 0.9529 221125_WJC_METTL3_EV_vs_WT_F06.11400.11400.3 0.00166 Sep-48 R.RLLEGEDAHLSSS.Q sp|P02533|K1C14_HUMAN 1 1412.6896 19.58 81021 11400 3 1412.687245 471.9038 "Keratin, type I cytoskeletal 14 OS=Homo sapiens OX=9606 GN=KRT14 PE=1 SV=4" 4.65 2176.5 - 1.55E+06 - - - -1.6472 - 1.854 0.353 - 99.3 1 1 0 -0.0023 13 0 0 0 2.42E+07 1.24E+06 - - - 4.1488 1 221125_WJC_METTL3_EV_vs_WT_F06.11402.11402.2 1.44E-07 24-Dec R.FNTANDDNVTQVR.A sp|P04040|CATA_HUMAN 1 1492.6906 12.03 81022 11402 2 1492.690148 747.3526 Catalase OS=Homo sapiens OX=9606 GN=CAT PE=1 SV=3 4.21 2176.8 - 4.11E+06 - - - -0.3256 - 2.93 0.663 - 610.7 1 2 0 -0.0005 13 0 0 0 5.91E+07 4.91E+06 - - - 6.6968 1 221125_WJC_METTL3_EV_vs_WT_F06.11403.11403.3 2.09E-09 14/68 R.AALAHSEEVTASQVAATK.T "sp|Q15149|PLEC_HUMAN,tr|H0YDN1|H0YDN1_HUMAN" 2 1782.9112 1.44 81023 11403 3 1782.912941 595.311 Plectin OS=Homo sapiens OX=9606 GN=PLEC PE=1 SV=3 5.4 2176.8 - 2.84E+06 - - - 0.981 - 3.236 0.608 - 247.5 1 2 0 0.0017 18 0 0 0 3.24E+07 2.25E+07 - - - 8.2423 0.9993 221125_WJC_METTL3_EV_vs_WT_F06.11404.11404.3 0.00302 Dec-44 R.QTVEADVNGLRR.V sp|P08779|K1C16_HUMAN 1 1356.711 581.61 81024 11404 3 1356.710437 453.2443 "Keratin, type I cytoskeletal 16 OS=Homo sapiens OX=9606 GN=KRT16 PE=1 SV=4" 6.07 2176.8 - 5.61E+06 - - - -0.3973 - 2.105 0.269 - 245.1 1 2 0 -0.0005 12 0 0 0 6.22E+09 1.07E+07 - - - 3.6021 0.9993 221125_WJC_METTL3_EV_vs_WT_F06.11405.11405.3 0.018 Aug-40 K.K[136.11]VTEELLTDNR[166.11].Y sp|Q9UHB9|SRP68_HUMAN 1 1334.7161 1.46 81025 11405 3 1334.716844 445.9126 Signal recognition particle subunit SRP68 OS=Homo sapiens OX=9606 GN=SRP68 PE=1 SV=2 4.68 2176.9 - 1.65E+06 - - - 0.5836 - 1.855 0.29 - 117.7 1 2 0 0.0008 11 0 0 0 3.21E+07 2.20E+07 - - - 3.5283 0.9999 221125_WJC_METTL3_EV_vs_WT_F06.11407.11407.2 2.70E-05 15/26 K.SSGASVTTQPTEFK[136.11].L "sp|Q9BY77|PDIP3_HUMAN,tr|F6VRR5|F6VRR5_HUMAN" 2 1446.7082 -1 81027 11407 2 1446.70662 724.3614 Polymerase delta-interacting protein 3 OS=Homo sapiens OX=9606 GN=POLDIP3 PE=1 SV=2 5.72 2177.1 - 1.24E+06 - - - -1.0845 - 2.802 0.546 - 702 1 2 0 -0.0016 14 0 0 0 0.00E+00 0.00E+00 - - - 5.6588 0.9946 221125_WJC_METTL3_EV_vs_WT_F06.11409.11409.2 0.00127 14/20 R.SR[166.11]NTDEMVELR[166.11].L "sp|P61978|HNRPK_HUMAN,tr|S4R457|S4R457_HUMAN,tr|Q5T6W2|Q5T6W2_HUMAN" 3 1368.6571 1.58 81029 11409 2 1368.661156 685.3358 Heterogeneous nuclear ribonucleoprotein K OS=Homo sapiens OX=9606 GN=HNRNPK PE=1 SV=1 4.68 2177.3 - 921898 - - - 2.9978 - 2.642 0.468 - 422 1 2 1 0.0041 11 0 0 0 2.42E+07 1.53E+07 - - - 5.1246 0.9998 221125_WJC_METTL3_EV_vs_WT_F06.11410.11410.2 1.17E-05 15/20 K.KVTEELLTDNR.Y sp|Q9UHB9|SRP68_HUMAN 1 1316.6936 2.12 81030 11410 2 1316.691445 659.3541 Signal recognition particle subunit SRP68 OS=Homo sapiens OX=9606 GN=SRP68 PE=1 SV=2 4.68 2177.4 - 920520 - - - -1.6329 - 2.525 0.529 - 419.3 1 2 0 -0.0021 11 0 0 0 9.67E+06 4.56E+06 - - - 5.4532 1 221125_WJC_METTL3_EV_vs_WT_F06.11411.11411.2 1.15E-09 16/32 T.QLQTTQSVEGATGSAVK.S "sp|Q14157|UBP2L_HUMAN,tr|F8W726|F8W726_HUMAN" 2 1703.869 3.63 81031 11411 2 1703.869817 852.9418 Ubiquitin-associated protein 2-like OS=Homo sapiens OX=9606 GN=UBAP2L PE=1 SV=2 6 2177.5 - 850871 - - - 0.4836 - 3.367 0.644 - 895 1 1 0 0.0008 17 0 0 0 2.35E+07 6.49E+06 - - - 6.7821 0.9968 221125_WJC_METTL3_EV_vs_WT_F06.11412.11412.3 1.38E-05 18/64 T.QLQTTQSVEGATGSAVK.S "sp|Q14157|UBP2L_HUMAN,tr|F8W726|F8W726_HUMAN" 2 1703.869 4.6 81032 11412 3 1703.869709 568.9636 Ubiquitin-associated protein 2-like OS=Homo sapiens OX=9606 GN=UBAP2L PE=1 SV=2 6 2177.7 - 564696 - - - 0.4202 - 2.966 0.465 - 381.8 1 1 0 0.0007 17 0 0 0 9.44E+06 2.05E+06 - - - 6.4707 1 221125_WJC_METTL3_EV_vs_WT_F06.11413.11413.2 6.46E-06 17/32 T.QLQTTQSVEGATGSAVK[136.11].S "sp|Q14157|UBP2L_HUMAN,tr|F8W726|F8W726_HUMAN" 2 1711.8832 3.63 81033 11413 2 1711.885246 856.9489 Ubiquitin-associated protein 2-like OS=Homo sapiens OX=9606 GN=UBAP2L PE=1 SV=2 6 2177.8 - 431443 - - - 1.1993 - 3.531 0.508 - 1271.7 1 1 0 0.0021 17 0 0 0 2.35E+07 6.49E+06 - - - 5.8941 1 221125_WJC_METTL3_EV_vs_WT_F06.11417.11417.2 0.000158 16/26 K.SSGASVTTQPTEFK.L "sp|Q9BY77|PDIP3_HUMAN,tr|F6VRR5|F6VRR5_HUMAN" 2 1438.694 1.45 81035 11417 2 1438.693803 720.3543 Polymerase delta-interacting protein 3 OS=Homo sapiens OX=9606 GN=POLDIP3 PE=1 SV=2 5.72 2178.3 - 6.04E+06 - - - -0.1293 - 3.001 0.579 - 847.1 1 2 0 -0.0002 14 0 0 0 3.14E+09 2.17E+09 - - - 6.0752 0.9979 221125_WJC_METTL3_EV_vs_WT_F06.11419.11419.2 0.0825 22-Aug R.QTVEADVNGLRR.V sp|P08779|K1C16_HUMAN 1 1356.711 1609.87 81037 11419 2 1356.711363 679.3628 "Keratin, type I cytoskeletal 16 OS=Homo sapiens OX=9606 GN=KRT16 PE=1 SV=4" 6.07 2178.4 - 2.99E+06 - - - 0.2852 - 1.464 0.234 - 72.5 1 2 0 0.0004 12 0 0 0 8.02E+08 4.98E+05 - - - 1.7721 0.9999 221125_WJC_METTL3_EV_vs_WT_F06.11420.11420.3 0.0412 Oct-48 R.ELLK[136.11]PNASVALHK[136.11].H sp|P43686|PRS6B_HUMAN 1 1434.8529 1.1 81038 11420 3 1434.85261 479.2916 26S proteasome regulatory subunit 6B OS=Homo sapiens OX=9606 GN=PSMC4 PE=1 SV=2 8.69 2178.5 - 2.95E+06 - - - -0.2363 - 2.061 0.407 - 100.8 1 2 0 -0.0003 13 0 0 0 9.17E+07 8.36E+07 - - - 5.0383 0.9999 221125_WJC_METTL3_EV_vs_WT_F06.11421.11421.3 0.00421 14/48 R.ELLKPNASVALHK.H sp|P43686|PRS6B_HUMAN 1 1418.8245 1.1 81039 11421 3 1418.823696 473.9488 26S proteasome regulatory subunit 6B OS=Homo sapiens OX=9606 GN=PSMC4 PE=1 SV=2 8.69 2178.6 - 2.27E+06 - - - -0.6012 - 2.573 0.394 - 212.3 1 2 0 -0.0009 13 0 0 0 9.17E+07 8.36E+07 - - - 5.4948 0.9999 221125_WJC_METTL3_EV_vs_WT_F06.11423.11423.3 1.66E-10 18/56 K.SEEVATKEELVADAK.V "sp|P07197|NFM_HUMAN,tr|E7ESP9|E7ESP9_HUMAN" 2 1617.8097 3.05 81041 11423 3 1617.81177 540.2772 Neurofilament medium polypeptide OS=Homo sapiens OX=9606 GN=NEFM PE=1 SV=3 4.25 2178.7 - 1.81E+06 - - - 1.2505 - 3.581 0.543 - 435.9 1 2 1 0.002 15 0 0 0 1.37E+08 4.49E+07 - - - 7.922 0.9998 221125_WJC_METTL3_EV_vs_WT_F06.11424.11424.3 7.93E-06 13/40 K.TR[166.11]LELEENQMK[136.11].R sp|Q9UG63|ABCF2_HUMAN 1 1407.7147 0.71 81042 11424 3 1407.714927 470.2455 ATP-binding cassette sub-family F member 2 OS=Homo sapiens OX=9606 GN=ABCF2 PE=1 SV=2 4.78 2178.8 - 1.56E+06 - - - 0.1726 - 2.537 0.44 - 352.7 1 2 1 0.0002 11 0 0 0 8.46E+06 1.18E+07 - - - 6.0903 0.9999 221125_WJC_METTL3_EV_vs_WT_F06.11427.11427.2 2.35E-06 22-Dec K.SQLNSQSVEITK[136.11].L sp|O60763|USO1_HUMAN 1 1340.7027 0.68 81045 11427 2 1340.703209 671.3586 General vesicular transport factor p115 OS=Homo sapiens OX=9606 GN=USO1 PE=1 SV=2 5.72 2179 - 1.01E+06 - - - 0.3729 - 2.598 0.554 - 416.1 1 2 0 0.0005 12 0 0 0 1.64E+07 2.39E+07 - - - 5.6448 0.9997 221125_WJC_METTL3_EV_vs_WT_F06.11428.11428.3 0.00021 14/48 R.LAGHLSEDPR[166.11]FPK[136.11].L sp|Q6ZRP7|QSOX2_HUMAN 1 1483.7902 1.08 81046 11428 3 1483.789887 495.604 Sulfhydryl oxidase 2 OS=Homo sapiens OX=9606 GN=QSOX2 PE=1 SV=3 6.75 2179.2 - 884953 - - - -0.2332 - 2.551 0.421 - 229.3 1 2 1 -0.0003 13 0 0 0 1.39E+07 1.28E+07 - - - 5.7727 0.9995 221125_WJC_METTL3_EV_vs_WT_F06.11431.11431.2 3.61E-05 14/20 K.K[136.11]VTEELLTDNR[166.11].Y sp|Q9UHB9|SRP68_HUMAN 1 1334.7161 2.12 81049 11431 2 1334.72057 668.3653 Signal recognition particle subunit SRP68 OS=Homo sapiens OX=9606 GN=SRP68 PE=1 SV=2 4.68 2179.5 - 621268 - - - 3.3752 - 2.515 0.552 - 718.6 1 2 0 0.0045 11 0 0 0 9.67E+06 4.56E+06 - - - 5.6116 0.9996 221125_WJC_METTL3_EV_vs_WT_F06.11432.11432.2 0.00601 20-Oct K.NDVNWSQPGEK.K "sp|Q13492|PICAL_HUMAN,tr|H0YE97|H0YE97_HUMAN,tr|H0YD48|H0YD48_HUMAN,tr|H0YEY8|H0YEY8_HUMAN,tr|H0YEF7|H0YEF7_HUMAN,tr|H0YCY1|H0YCY1_HUMAN,tr|H0YEH1|H0YEH1_HUMAN" 7 1272.5735 0.38 81050 11432 2 1272.573793 637.294 Phosphatidylinositol-binding clathrin assembly protein OS=Homo sapiens OX=9606 GN=PICALM PE=1 SV=2 4.37 2179.6 - 559007 - - - 0.2467 - 1.649 0.406 - 170.1 1 2 0 0.0003 11 0 0 0 3.38E+07 8.84E+07 - - - 3.3927 0.9389 221125_WJC_METTL3_EV_vs_WT_F06.11435.11435.2 1.27 30-Apr K.LPSRPGAQGVEPQNLR.T "sp|Q8WXI9|P66B_HUMAN,tr|A0A0U1RRM1|A0A0U1RRM1_HUMAN" 2 1717.9224 2.52 81053 11435 2 1717.919555 859.9685 Transcriptional repressor p66-beta OS=Homo sapiens OX=9606 GN=GATAD2B PE=1 SV=1 9.6 2180 - 306339 - - - -1.6363 - 1.101 0.112 - 11.5 6 2 0 -0.0028 16 0 0 0 3.61E+07 1.43E+07 - - - -0.2437 0.9999 221125_WJC_METTL3_EV_vs_WT_F06.11438.11438.3 1.45E-08 20/52 R.LR[166.11]QEEPQSLQAAVR[166.11].T "sp|P29590|PML_HUMAN,tr|H3BUJ5|H3BUJ5_HUMAN,tr|H3BT29|H3BT29_HUMAN,tr|H3BVD2|H3BVD2_HUMAN,tr|H3BT57|H3BT57_HUMAN" 5 1643.8858 1.13 81055 11438 3 1643.88634 548.9692 Protein PML OS=Homo sapiens OX=9606 GN=PML PE=1 SV=3 6.14 2180.4 - 3.49E+06 - - - 0.3236 - 3.33 0.551 - 722.6 1 2 1 0.0005 14 0 0 0 5.56E+07 4.93E+07 - - - 7.8799 1 221125_WJC_METTL3_EV_vs_WT_F06.11439.11439.2 3.87E-07 13/34 R.AALAHSEEVTASQVAATK.T "sp|Q15149|PLEC_HUMAN,tr|H0YDN1|H0YDN1_HUMAN" 2 1782.9112 -1 81056 11439 2 1782.910083 892.4629 Plectin OS=Homo sapiens OX=9606 GN=PLEC PE=1 SV=3 5.4 2180.5 - 247692 - - - -0.622 - 2.786 0.626 - 317.4 1 2 0 -0.0011 18 0 0 0 0.00E+00 0.00E+00 - - - 6.1833 1 221125_WJC_METTL3_EV_vs_WT_F06.11441.11441.3 1.17E-08 15/56 K.SEEVATK[136.11]EELVADAK[136.11].V "sp|P07197|NFM_HUMAN,tr|E7ESP9|E7ESP9_HUMAN" 2 1633.8381 3.12 81058 11441 3 1633.837758 545.62 Neurofilament medium polypeptide OS=Homo sapiens OX=9606 GN=NEFM PE=1 SV=3 4.25 2180.7 - 1.88E+06 - - - -0.2381 - 3.557 0.657 - 317 1 2 1 -0.0004 15 0 0 0 1.37E+08 4.38E+07 - - - 9.1759 0.9987 221125_WJC_METTL3_EV_vs_WT_F06.11442.11442.3 0.0775 Oct-40 K.DDSVR[166.11]PNMTLK[136.11].A sp|Q709C8|VP13C_HUMAN 1 1292.6514 4.97 81059 11442 3 1292.652856 431.8911 Vacuolar protein sorting-associated protein 13C OS=Homo sapiens OX=9606 GN=VPS13C PE=1 SV=1 5.96 2180.8 - 1.35E+06 - - - 1.1604 - 1.782 0.276 - 147.6 1 2 0 0.0015 11 0 0 0 8.21E+07 1.65E+07 - - - 3.258 0.9456 221125_WJC_METTL3_EV_vs_WT_F06.11444.11444.2 0.0194 20-Nov Q.TVEADVNGLRR.V sp|P08779|K1C16_HUMAN 1 1228.6524 10.6 81061 11444 2 1228.651418 615.3335 "Keratin, type I cytoskeletal 16 OS=Homo sapiens OX=9606 GN=KRT16 PE=1 SV=4" 5.74 2181 - 857474 - - - -0.7976 - 1.559 0.306 - 165.7 1 1 0 -0.001 11 0 0 0 5.36E+07 5.05E+06 - - - 2.5021 0.9999 221125_WJC_METTL3_EV_vs_WT_F06.11445.11445.3 4.75E-05 13/44 R.NIGISAHIDSGK[136.11].T "sp|Q96RP9|EFGM_HUMAN,tr|F8WAU4|F8WAU4_HUMAN,tr|C9IZ01|C9IZ01_HUMAN" 3 1218.6448 0.67 81062 11445 3 1218.643862 407.2222 "Elongation factor G, mitochondrial OS=Homo sapiens OX=9606 GN=GFM1 PE=1 SV=2" 6.74 2181.2 - 767423 - - - -0.7697 - 2.371 0.433 - 137.3 1 2 0 -0.0009 12 0 0 0 1.47E+07 2.21E+07 - - - 5.7602 1 221125_WJC_METTL3_EV_vs_WT_F06.11448.11448.2 3.71E-11 17/28 K.SEEVATKEELVADAK.V "sp|P07197|NFM_HUMAN,tr|E7ESP9|E7ESP9_HUMAN" 2 1617.8097 5.91 81065 11448 2 1617.81576 809.9121 Neurofilament medium polypeptide OS=Homo sapiens OX=9606 GN=NEFM PE=1 SV=3 4.25 2181.6 - 362755 - - - 3.7168 - 3.666 0.702 - 1055.6 1 2 1 0.006 15 0 0 0 1.89E+07 3.19E+06 - - - 7.418 0.9997 221125_WJC_METTL3_EV_vs_WT_F06.11449.11449.2 5.39E-06 30-Aug K.LPSR[166.11]PGAQGVEPQNLR[166.11].T "sp|Q8WXI9|P66B_HUMAN,tr|A0A0U1RRM1|A0A0U1RRM1_HUMAN" 2 1737.9389 2.52 81066 11449 2 1737.939273 869.9767 Transcriptional repressor p66-beta OS=Homo sapiens OX=9606 GN=GATAD2B PE=1 SV=1 9.6 2181.7 - 231540 - - - 0.2112 - 1.784 0.451 - 46.9 1 2 0 0.0004 16 0 0 0 3.61E+07 1.43E+07 - - - 3.7951 0.9999 221125_WJC_METTL3_EV_vs_WT_F06.11455.11455.2 7.17E-05 14/22 K.SQLNSQSVEITK.L sp|O60763|USO1_HUMAN 1 1332.6885 0.66 81070 11455 2 1332.688241 667.3515 General vesicular transport factor p115 OS=Homo sapiens OX=9606 GN=USO1 PE=1 SV=2 5.72 2182.4 - 1.62E+06 - - - -0.2011 - 2.877 0.504 - 597.9 1 2 0 -0.0003 12 0 0 0 1.64E+07 2.46E+07 - - - 5.5439 0.9883 221125_WJC_METTL3_EV_vs_WT_F06.11457.11457.2 6.91 16-Jul K.DLPEHAVLK.M "sp|Q00839|HNRPU_HUMAN,tr|A0A1W2PQL0|A0A1W2PQL0_HUMAN,tr|A0A1W2PPL4|A0A1W2PPL4_HUMAN,tr|A0A1W2PQ74|A0A1W2PQ74_HUMAN,tr|Q5RI18|Q5RI18_HUMAN,tr|A0A1W2PP35|A0A1W2PP35_HUMAN,tr|A0A1W2PPS1|A0A1W2PPS1_HUMAN,tr|A0A1W2PRZ7|A0A1W2PRZ7_HUMAN,tr|A0A1W2PPH7|A0A1W2PPH7_HUMAN,tr|A0A1W2PQD4|A0A1W2PQD4_HUMAN,tr|A0A1W2PP34|A0A1W2PP34_HUMAN,tr|A0A1X7SBS1|A0A1X7SBS1_HUMAN" 12 1020.5604 1.79 81072 11457 2 1020.559927 511.2875 Heterogeneous nuclear ribonucleoprotein U OS=Homo sapiens OX=9606 GN=HNRNPU PE=1 SV=6 5.32 2182.5 - 2.22E+06 - - - -0.4586 - 1.224 0.122 - 127.6 1 2 0 -0.0005 9 0 0 0 2.77E+07 1.55E+07 - - - 0.5267 0.9999 221125_WJC_METTL3_EV_vs_WT_F06.11459.11459.3 6.10E-05 Dec-40 K.K[136.11]VTQLDLDGPK[136.11].E sp|Q13442|HAP28_HUMAN 1 1228.6998 0.66 81074 11459 3 1228.697301 410.5739 28 kDa heat- and acid-stable phosphoprotein OS=Homo sapiens OX=9606 GN=PDAP1 PE=1 SV=1 5.96 2182.6 - 1.27E+06 - - - -2.0363 - 2.567 0.437 - 221.9 1 2 0 -0.0025 11 0 0 0 1.14E+07 1.73E+07 - - - 6.0896 0.9994 221125_WJC_METTL3_EV_vs_WT_F06.11466.11466.3 0.111 Nov-32 R.KQQLEVELR.Q sp|P15924|DESP_HUMAN 1 1141.6455 13.75 81079 11466 3 1141.643232 381.5558 Desmoplakin OS=Homo sapiens OX=9606 GN=DSP PE=1 SV=3 6.14 2183.6 - 2.47E+06 - - - -2.0059 - 2.254 0.288 - 261.9 1 2 0 -0.0023 9 0 0 0 7.01E+07 5.10E+06 - - - 4.1996 0.9804 221125_WJC_METTL3_EV_vs_WT_F06.11470.11470.3 0.426 Dec-60 K.LPSRPGAQGVEPQNLR[166.11].T "sp|Q8WXI9|P66B_HUMAN,tr|A0A0U1RRM1|A0A0U1RRM1_HUMAN" 2 1727.9306 - 81083 11470 3 1727.925757 576.9842 Transcriptional repressor p66-beta OS=Homo sapiens OX=9606 GN=GATAD2B PE=1 SV=1 9.6 2184 - 631500 - - - -2.8236 - 1.765 0.19 - 157.9 1 2 0 -0.0049 16 0 0 0 - - - - - 2.1148 0.7953 221125_WJC_METTL3_EV_vs_WT_F06.11474.11474.2 0.598 14-Jul K.GVWVNGLR.V "sp|Q9Y6R7|FCGBP_HUMAN,tr|A0A087WXI2|A0A087WXI2_HUMAN" 2 899.4977 999 81085 11474 2 899.494288 450.7561 IgGFc-binding protein OS=Homo sapiens OX=9606 GN=FCGBP PE=1 SV=3 9.75 2184.5 - 5.80E+06 - - - -3.8333 - 1.316 0.021 - 99.6 2 2 0 -0.0034 8 0 0 0 5.85E+07 0.00E+00 - - - -0.1113 0.9986 221125_WJC_METTL3_EV_vs_WT_F06.11475.11475.3 0.0371 Aug-44 K.SVHFPGQAVGTR[166.11].R "sp|Q06210|GFPT1_HUMAN,tr|A0A6I8PRN4|A0A6I8PRN4_HUMAN,tr|A0A6I8PTT9|A0A6I8PTT9_HUMAN" 3 1264.6552 1.19 81086 11475 3 1264.653165 422.559 Glutamine--fructose-6-phosphate aminotransferase [isomerizing] 1 OS=Homo sapiens OX=9606 GN=GFPT1 PE=1 SV=3 9.49 2184.6 - 3.05E+06 - - - -1.6004 - 1.868 0.271 - 117.1 1 2 0 -0.002 12 0 0 0 1.54E+08 1.30E+08 - - - 3.2929 0.9997 221125_WJC_METTL3_EV_vs_WT_F06.11477.11477.3 0.00196 Dec-48 K.AVLQPHENIVPNK.A "sp|O60315|ZEB2_HUMAN,tr|U3KQ51|U3KQ51_HUMAN,tr|E7EUW9|E7EUW9_HUMAN,tr|A0JP08|A0JP08_HUMAN,tr|A0A1B0GW50|A0A1B0GW50_HUMAN,tr|A0A1B0GV02|A0A1B0GV02_HUMAN,tr|A0A1B0GVV8|A0A1B0GVV8_HUMAN" 7 1457.7991 3.37 81088 11477 3 1457.79897 486.9403 Zinc finger E-box-binding homeobox 2 OS=Homo sapiens OX=9606 GN=ZEB2 PE=1 SV=1 6.79 2184.8 - 1.71E+06 - - - -0.0638 - 2.022 0.333 - 155.2 1 2 0 -0.0001 13 0 0 0 3.51E+07 1.04E+07 - - - 4.1616 0.9982 221125_WJC_METTL3_EV_vs_WT_F06.11478.11478.3 0.16 Nov-40 K.NFASNHIQLQK.Y "sp|Q17RY0|CPEB4_HUMAN,tr|H0YBG1|H0YBG1_HUMAN,tr|E5RJM0|E5RJM0_HUMAN,tr|B7ZLQ8|B7ZLQ8_HUMAN" 4 1298.6731 1.5 81089 11478 3 1298.671266 433.8983 Cytoplasmic polyadenylation element-binding protein 4 OS=Homo sapiens OX=9606 GN=CPEB4 PE=1 SV=1 8.76 2184.9 - 1.38E+06 - - - -1.4384 - 1.912 0.239 - 153.2 1 2 0 -0.0019 11 0 0 0 2.95E+07 1.96E+07 - - - 3.0454 0.9999 221125_WJC_METTL3_EV_vs_WT_F06.11479.11479.3 7.43E-06 15/40 K.VADMALHYANK[136.11].Y "sp|P50990|TCPQ_HUMAN,tr|H7C4C8|H7C4C8_HUMAN" 2 1239.6161 0.29 81090 11479 3 1239.61671 414.2127 T-complex protein 1 subunit theta OS=Homo sapiens OX=9606 GN=CCT8 PE=1 SV=4 6.71 2185 - 1.24E+06 - - - 0.4574 - 2.383 0.414 - 249.6 1 2 0 0.0006 11 0 0 0 3.92E+06 1.33E+07 - - - 5.6224 0.9992 221125_WJC_METTL3_EV_vs_WT_F06.11480.11480.2 1.84E-05 13/26 K.NGTLSVSDTTVGSK[136.11].Q sp|Q9BSC4|NOL10_HUMAN 1 1372.6925 1.28 81091 11480 2 1372.687113 687.3535 Nucleolar protein 10 OS=Homo sapiens OX=9606 GN=NOL10 PE=1 SV=1 5.84 2185.1 - 980545 - - - -3.9521 - 2.711 0.528 - 595.7 1 2 0 -0.0054 14 0 0 0 2.47E+07 1.93E+07 - - - 5.4418 1 221125_WJC_METTL3_EV_vs_WT_F06.11481.11481.2 6.93E-07 13/26 K.NGTLSVSDTTVGSK.Q sp|Q9BSC4|NOL10_HUMAN 1 1364.6783 1.28 81092 11481 2 1364.680404 683.3464 Nucleolar protein 10 OS=Homo sapiens OX=9606 GN=NOL10 PE=1 SV=1 5.84 2185.3 - 621137 - - - 1.5139 - 2.77 0.588 - 634.2 1 2 0 0.0021 14 0 0 0 2.47E+07 1.93E+07 - - - 5.9401 0.9999 221125_WJC_METTL3_EV_vs_WT_F06.11483.11483.2 5.24E-06 20-Nov K.NDVNWSQPGEK[136.11].K "sp|Q13492|PICAL_HUMAN,tr|H0YE97|H0YE97_HUMAN,tr|H0YD48|H0YD48_HUMAN,tr|H0YEY8|H0YEY8_HUMAN,tr|H0YEF7|H0YEF7_HUMAN,tr|H0YCY1|H0YCY1_HUMAN,tr|H0YEH1|H0YEH1_HUMAN" 7 1280.5877 3.29 81094 11483 2 1280.588401 641.3011 Phosphatidylinositol-binding clathrin assembly protein OS=Homo sapiens OX=9606 GN=PICALM PE=1 SV=2 4.37 2185.5 - 1.15E+06 - - - 0.5638 - 2.09 0.504 - 436.6 1 2 0 0.0007 11 0 0 0 3.26E+07 9.91E+06 - - - 4.7575 0.9999 221125_WJC_METTL3_EV_vs_WT_F06.11486.11486.3 3.37E-05 13/44 K.SVHFPGQAVGTR.R "sp|Q06210|GFPT1_HUMAN,tr|A0A6I8PRN4|A0A6I8PRN4_HUMAN,tr|A0A6I8PTT9|A0A6I8PTT9_HUMAN" 3 1254.6469 1.18 81095 11486 3 1254.643911 419.2229 Glutamine--fructose-6-phosphate aminotransferase [isomerizing] 1 OS=Homo sapiens OX=9606 GN=GFPT1 PE=1 SV=3 9.49 2185.9 - 5.33E+06 - - - -2.3975 - 2.513 0.446 - 284.1 1 2 0 -0.003 12 0 0 0 1.53E+08 1.30E+08 - - - 6.0658 0.8153 221125_WJC_METTL3_EV_vs_WT_F06.11487.11487.2 0.0435 12-Aug L.PEHAVLK.M "sp|Q00839|HNRPU_HUMAN,tr|A0A1W2PQL0|A0A1W2PQL0_HUMAN,tr|A0A1W2PPL4|A0A1W2PPL4_HUMAN,tr|A0A1W2PQ74|A0A1W2PQ74_HUMAN,tr|Q5RI18|Q5RI18_HUMAN,tr|A0A1W2PP35|A0A1W2PP35_HUMAN,tr|A0A1W2PPS1|A0A1W2PPS1_HUMAN,tr|A0A1W2PRZ7|A0A1W2PRZ7_HUMAN,tr|A0A1W2PPH7|A0A1W2PPH7_HUMAN,tr|A0A1W2PQD4|A0A1W2PQD4_HUMAN,tr|A0A1W2PP34|A0A1W2PP34_HUMAN,tr|A0A1X7SBS1|A0A1X7SBS1_HUMAN" 12 792.4494 0.83 81096 11487 2 792.447245 397.232 Heterogeneous nuclear ribonucleoprotein U OS=Homo sapiens OX=9606 GN=HNRNPU PE=1 SV=6 7.17 2186 - 724437 - - - -2.7043 - 1.793 0.195 - 218.4 1 1 0 -0.0021 7 0 0 0 1.90E+07 2.28E+07 - - - 2.3307 0.9997 221125_WJC_METTL3_EV_vs_WT_F06.11488.11488.2 0.000245 13/16 K.KGDIIQLQR.R "sp|P07814|SYEP_HUMAN,tr|V9GYZ6|V9GYZ6_HUMAN" 2 1069.6244 0.88 81097 11488 2 1069.624469 535.8195 Bifunctional glutamate\proline--tRNA ligase OS=Homo sapiens OX=9606 GN=EPRS1 PE=1 SV=5 8.75 2186.2 - 1.63E+06 - - - 0.0711 - 2.304 0.283 - 675.7 1 2 0 0.0001 9 0 0 0 4.60E+07 5.21E+07 - - - 3.5459 1 221125_WJC_METTL3_EV_vs_WT_F06.11491.11491.2 3.36E-08 14/26 K.ELNNTC[160.03]EPVVTQPK[136.11].P "sp|Q92598|HS105_HUMAN,tr|Q5TBM3|Q5TBM3_HUMAN,tr|A0A0A0MSM0|A0A0A0MSM0_HUMAN" 3 1635.8018 0.001 81100 11491 2 1635.803936 818.9082 Heat shock protein 105 kDa OS=Homo sapiens OX=9606 GN=HSPH1 PE=1 SV=1 4.53 2186.5 - 721417 - - - 1.3229 - 2.783 0.602 - 708.4 1 1 0 0.0022 14 0 0 0 0.00E+00 1.30E+07 - - - 6.0552 1 221125_WJC_METTL3_EV_vs_WT_F06.11496.11496.2 1.59E-08 13/26 Y.EIDAC[160.03]MDSEAPGSK[136.11].D "sp|Q86U44|MTA70_HUMAN,tr|H0YFV6|H0YFV6_HUMAN" 2 1516.6265 0.02 81103 11496 2 1517.624881 759.3205 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 3.92 2187.1 - 4.21E+06 - - - 658.2847 - 2.423 0.685 - 375.4 1 1 0 0.9984 14 0 0 0 5.74E+06 3.39E+08 - - - 6.0078 0.9996 221125_WJC_METTL3_EV_vs_WT_F06.11497.11497.3 0.000702 Nov-40 K.K[136.11]ATVNLLGEEK[136.11].K sp|Q00765|REEP5_HUMAN 1 1216.6998 0.88 81104 11497 3 1216.697226 406.5739 Receptor expression-enhancing protein 5 OS=Homo sapiens OX=9606 GN=REEP5 PE=1 SV=3 6.14 2187.2 - 1.92E+06 - - - -2.118 - 2.181 0.338 - 126.1 1 2 0 -0.0026 11 0 0 0 2.75E+07 3.13E+07 - - - 4.5229 0.8475 221125_WJC_METTL3_EV_vs_WT_F06.11498.11498.2 0.00392 22-Nov K.SVHFPGQAVGTR.R "sp|Q06210|GFPT1_HUMAN,tr|A0A6I8PRN4|A0A6I8PRN4_HUMAN,tr|A0A6I8PTT9|A0A6I8PTT9_HUMAN" 3 1254.6469 1.42 81105 11498 2 1255.653727 628.3307 Glutamine--fructose-6-phosphate aminotransferase [isomerizing] 1 OS=Homo sapiens OX=9606 GN=GFPT1 PE=1 SV=3 9.49 2187.3 - 1.13E+06 - - - 802.4632 - 1.646 0.301 - 229.2 1 2 0 1.0068 12 0 0 0 2.70E+07 1.91E+07 - - - 2.2593 0.79 221125_WJC_METTL3_EV_vs_WT_F06.11499.11499.3 0.0333 13/52 K.SSGASVTTQPTEFK[136.11].L "sp|Q9BY77|PDIP3_HUMAN,tr|F6VRR5|F6VRR5_HUMAN" 2 1446.7082 1.02 81106 11499 3 1446.705738 483.2433 Polymerase delta-interacting protein 3 OS=Homo sapiens OX=9606 GN=POLDIP3 PE=1 SV=2 5.72 2187.4 - 860059 - - - -1.6942 - 1.765 0.012 - 207.1 1 2 0 -0.0024 14 0 0 0 2.21E+07 2.17E+07 - - - 0.183 0.9983 221125_WJC_METTL3_EV_vs_WT_F06.11501.11501.3 0.0296 Oct-40 K.ESGASHLSFPK[136.11].N "sp|Q9BRD0|BUD13_HUMAN,tr|H7C462|H7C462_HUMAN" 2 1166.5811 1.27 81108 11501 3 1166.57925 389.8677 BUD13 homolog OS=Homo sapiens OX=9606 GN=BUD13 PE=1 SV=1 6.85 2187.7 - 702683 - - - -1.6175 - 2.021 0.237 - 135.6 1 2 0 -0.0019 11 0 0 0 1.88E+07 1.47E+07 - - - 3.1806 0.9996 221125_WJC_METTL3_EV_vs_WT_F06.11504.11504.2 0.0147 14/16 K.K[136.11]GDIIQLQR[166.11].R "sp|P07814|SYEP_HUMAN,tr|V9GYZ6|V9GYZ6_HUMAN" 2 1087.6469 0.88 81109 11504 2 1087.645526 544.8307 Bifunctional glutamate\proline--tRNA ligase OS=Homo sapiens OX=9606 GN=EPRS1 PE=1 SV=5 8.75 2188.1 - 4.36E+06 - - - -1.2293 - 2.566 0.265 - 799.5 1 2 0 -0.0013 9 0 0 0 4.60E+07 5.21E+07 - - - 3.7241 1 221125_WJC_METTL3_EV_vs_WT_F06.11505.11505.3 4.03E-05 Dec-44 K.IMLDSSNLQHQK[136.11].L "sp|Q9Y2L1|RRP44_HUMAN,tr|G3V1J5|G3V1J5_HUMAN" 2 1420.7224 1.37 81110 11505 3 1420.721903 474.5814 Exosome complex exonuclease RRP44 OS=Homo sapiens OX=9606 GN=DIS3 PE=1 SV=2 6.74 2188.1 - 3.06E+06 - - - -0.3491 - 2.65 0.486 - 165.4 1 2 0 -0.0005 12 0 0 0 6.68E+07 4.88E+07 - - - 6.6596 0.9996 221125_WJC_METTL3_EV_vs_WT_F06.11508.11508.2 5.47E-06 26-Nov R.EVLNEEDEVQPNGK[136.11].L "sp|O95573|ACSL3_HUMAN,tr|A0A7P0TBB1|A0A7P0TBB1_HUMAN,tr|A0A7P0TBL9|A0A7P0TBL9_HUMAN,tr|A0A7P0TB52|A0A7P0TB52_HUMAN,tr|A0A7P0T905|A0A7P0T905_HUMAN,tr|A0A7P0TA76|A0A7P0TA76_HUMAN,tr|H7BYZ7|H7BYZ7_HUMAN" 7 1606.7566 1.31 81113 11508 2 1606.752891 804.3856 Fatty acid CoA ligase Acsl3 OS=Homo sapiens OX=9606 GN=ACSL3 PE=1 SV=3 3.91 2188.5 - 786747 - - - -2.3053 - 1.791 0.565 - 147.5 1 2 0 -0.0037 14 0 0 0 1.70E+07 1.30E+07 - - - 4.6754 0.9998 221125_WJC_METTL3_EV_vs_WT_F06.11511.11511.3 0.0026 Dec-40 K.KATVNLLGEEK.K sp|Q00765|REEP5_HUMAN 1 1200.6714 0.88 81114 11511 3 1200.66934 401.2311 Receptor expression-enhancing protein 5 OS=Homo sapiens OX=9606 GN=REEP5 PE=1 SV=3 6.14 2188.9 - 1.51E+06 - - - -1.7182 - 2.204 0.385 - 176.8 1 2 0 -0.0021 11 0 0 0 2.75E+07 3.13E+07 - - - 5.0768 0.9994 221125_WJC_METTL3_EV_vs_WT_F06.11512.11512.2 0.00261 22-Oct K.SVHFPGQAVGTR[166.11].R "sp|Q06210|GFPT1_HUMAN,tr|A0A6I8PRN4|A0A6I8PRN4_HUMAN,tr|A0A6I8PTT9|A0A6I8PTT9_HUMAN" 3 1264.6552 1.42 81115 11512 2 1264.653262 633.3349 Glutamine--fructose-6-phosphate aminotransferase [isomerizing] 1 OS=Homo sapiens OX=9606 GN=GFPT1 PE=1 SV=3 9.49 2189 - 904325 - - - -1.5237 - 1.97 0.342 - 241.5 1 2 0 -0.0019 12 0 0 0 2.70E+07 1.91E+07 - - - 3.3504 1 221125_WJC_METTL3_EV_vs_WT_F06.11515.11515.3 7.51E-08 13/52 R.VTEFGGELHEDGGK[136.11].L "sp|Q9UFW8|CGBP1_HUMAN,tr|C9JUJ0|C9JUJ0_HUMAN" 2 1481.6878 0.96 81118 11515 3 1481.685141 494.9032 CGG triplet repeat-binding protein 1 OS=Homo sapiens OX=9606 GN=CGGBP1 PE=1 SV=2 4.4 2189.2 - 2.47E+06 - - - -1.7858 - 2.705 0.517 - 250.5 1 2 0 -0.0026 14 0 0 0 5.60E+07 5.82E+07 - - - 6.9478 0.9998 221125_WJC_METTL3_EV_vs_WT_F06.11516.11516.2 0.000526 20-Dec K.QQLDLTEQQGR.K sp|Q08378|GOGA3_HUMAN 1 1314.6528 1.05 81119 11516 2 1314.654065 658.3337 Golgin subfamily A member 3 OS=Homo sapiens OX=9606 GN=GOLGA3 PE=1 SV=2 4.37 2189.3 - 1.22E+06 - - - 0.9683 - 2.554 0.43 - 801.8 1 2 0 0.0013 11 0 0 0 1.90E+07 1.81E+07 - - - 4.7532 1 221125_WJC_METTL3_EV_vs_WT_F06.11518.11518.3 3.46E-05 13/40 K.ESGASHLSFPK.N "sp|Q9BRD0|BUD13_HUMAN,tr|H7C462|H7C462_HUMAN" 2 1158.5669 1.24 81121 11518 3 1158.565511 387.1963 BUD13 homolog OS=Homo sapiens OX=9606 GN=BUD13 PE=1 SV=1 6.85 2189.6 - 776735 - - - -1.2308 - 2.595 0.438 - 286.1 1 2 0 -0.0014 11 0 0 0 1.94E+07 1.56E+07 - - - 6.1318 0.9937 221125_WJC_METTL3_EV_vs_WT_F06.11521.11521.2 6.37E-05 20-Nov R.QSVENDIHGLR[166.11].K "sp|P05783|K1C18_HUMAN,tr|F8VZY9|F8VZY9_HUMAN" 2 1276.6399 2.16 81124 11521 2 1277.642934 639.3272 "Keratin, type I cytoskeletal 18 OS=Homo sapiens OX=9606 GN=KRT18 PE=1 SV=2" 5.32 2190 - 481335 - - - 785.6569 - 2.414 0.452 - 515 1 2 0 1.003 11 0 0 0 2.91E+07 1.35E+07 - - - 4.4486 0.9994 221125_WJC_METTL3_EV_vs_WT_F06.11522.11522.2 0.000715 18-Jul K.HIYYITGETK.D "sp|Q58FG0|HS905_HUMAN,sp|P07900|HS90A_HUMAN" 2 1223.6186 0.56 81125 11522 2 1223.618186 612.8166 Putative heat shock protein HSP 90-alpha A5 OS=Homo sapiens OX=9606 GN=HSP90AA5P PE=2 SV=1 6.75 2190.1 - 466315 - - - -0.3702 - 1.662 0.323 - 120.6 1 2 0 -0.0005 10 0 0 0 7.16E+06 1.29E+07 - - - 2.8446 0.9995 221125_WJC_METTL3_EV_vs_WT_F06.11526.11526.3 0.0141 Sep-40 K.DMAQSIYRPSK.N "sp|Q13573|SNW1_HUMAN,tr|G3V4X8|G3V4X8_HUMAN,tr|G3V3A4|G3V3A4_HUMAN" 3 1294.634 1.08 81127 11526 3 1294.632788 432.5519 SNW domain-containing protein 1 OS=Homo sapiens OX=9606 GN=SNW1 PE=1 SV=1 8.59 2190.6 - 2.86E+06 - - - -0.9138 - 1.465 0.382 - 79.5 1 2 0 -0.0012 11 0 0 0 4.83E+07 4.45E+07 - - - 3.8834 1 221125_WJC_METTL3_EV_vs_WT_F06.11527.11527.3 1.32E-05 16/48 R.LGSLDC[160.03]SHSFSSR.T "sp|Q8NDV7|TNR6A_HUMAN,tr|H7C269|H7C269_HUMAN" 2 1451.6463 1.37 81128 11527 3 1451.647605 484.8894 Trinucleotide repeat-containing gene 6A protein OS=Homo sapiens OX=9606 GN=TNRC6A PE=1 SV=2 6.74 2190.7 - 2.38E+06 - - - 0.8804 - 3.462 0.553 - 577.3 1 2 0 0.0013 13 0 0 0 3.28E+07 2.40E+07 - - - 8.0721 0.9999 221125_WJC_METTL3_EV_vs_WT_F06.11528.11528.3 0.227 13/48 R.LGSLDC[160.03]SHSFSSR[166.11].T "sp|Q8NDV7|TNR6A_HUMAN,tr|H7C269|H7C269_HUMAN" 2 1461.6546 1.37 81129 11528 3 1461.651602 488.2255 Trinucleotide repeat-containing gene 6A protein OS=Homo sapiens OX=9606 GN=TNRC6A PE=1 SV=2 6.74 2190.8 - 1.66E+06 - - - -2.049 - 3.103 0.443 - 306.7 1 2 0 -0.003 13 0 0 0 3.28E+07 2.40E+07 - - - 6.5484 1 221125_WJC_METTL3_EV_vs_WT_F06.11530.11530.2 1.03E-06 13/24 K.DINAYNC[160.03]EEPTEK[136.11].L sp|P30041|PRDX6_HUMAN 1 1589.6759 0.96 81131 11530 2 1589.672261 795.8452 Peroxiredoxin-6 OS=Homo sapiens OX=9606 GN=PRDX6 PE=1 SV=3 4 2191 - 932445 - - - -2.2904 - 2.58 0.656 - 534.2 1 2 0 -0.0036 13 0 0 0 4.16E+07 4.32E+07 - - - 6.3176 0.9999 221125_WJC_METTL3_EV_vs_WT_F06.11531.11531.2 2.10E-06 26-Oct R.VTEFGGELHEDGGK[136.11].L "sp|Q9UFW8|CGBP1_HUMAN,tr|C9JUJ0|C9JUJ0_HUMAN" 2 1481.6878 0.67 81132 11531 2 1481.686715 741.8512 CGG triplet repeat-binding protein 1 OS=Homo sapiens OX=9606 GN=CGGBP1 PE=1 SV=2 4.4 2191.1 - 346458 - - - -0.7235 - 2.252 0.602 - 332.3 1 2 0 -0.0011 14 0 0 0 3.29E+06 4.89E+06 - - - 5.5243 0.9926 221125_WJC_METTL3_EV_vs_WT_F06.11535.11535.3 0.0749 Sep-40 K.DMAQSIYR[166.11]PSK[136.11].N "sp|Q13573|SNW1_HUMAN,tr|G3V4X8|G3V4X8_HUMAN,tr|G3V3A4|G3V3A4_HUMAN" 3 1312.6564 1.11 81134 11535 3 1312.65816 438.5594 SNW domain-containing protein 1 OS=Homo sapiens OX=9606 GN=SNW1 PE=1 SV=1 8.59 2191.7 - 2.47E+06 - - - 1.3096 - 1.501 0.22 - 85 1 2 0 0.0017 11 0 0 0 4.79E+07 4.31E+07 - - - 2.1461 0.9932 221125_WJC_METTL3_EV_vs_WT_F06.11536.11536.3 0.0378 Nov-44 R.QTASIFK[136.11]QPVTK[136.11].V "sp|Q9UBB5|MBD2_HUMAN,sp|O95983|MBD3_HUMAN,tr|A0A087X1H1|A0A087X1H1_HUMAN,tr|K7EIE8|K7EIE8_HUMAN,tr|A0A087WT34|A0A087WT34_HUMAN,tr|A0A0A0MTS6|A0A0A0MTS6_HUMAN,tr|J3KSA7|J3KSA7_HUMAN" 7 1362.7842 1.21 81135 11536 3 1362.784071 455.2687 Methyl-CpG-binding domain protein 2 OS=Homo sapiens OX=9606 GN=MBD2 PE=1 SV=1 10 2191.7 - 1.35E+06 - - - -0.0954 - 1.856 0.249 - 108.9 1 2 1 -0.0001 12 0 0 0 2.91E+07 2.40E+07 - - - 3.0302 0.9998 221125_WJC_METTL3_EV_vs_WT_F06.11537.11537.3 0.00273 Oct-40 K.TSLMNQYVNKK.F "sp|P51149|RAB7A_HUMAN,tr|C9J592|C9J592_HUMAN,tr|C9J4V0|C9J4V0_HUMAN,tr|C9J7D1|C9J7D1_HUMAN,tr|A0A6Q8PH84|A0A6Q8PH84_HUMAN,tr|C9J8S3|C9J8S3_HUMAN,tr|C9IZZ0|C9IZZ0_HUMAN,tr|C9J4S4|C9J4S4_HUMAN,tr|A0A6Q8PG52|A0A6Q8PG52_HUMAN" 9 1324.6809 1.04 81136 11537 3 1324.679707 442.5676 Ras-related protein Rab-7a OS=Homo sapiens OX=9606 GN=RAB7A PE=1 SV=1 9.7 2191.8 - 2.87E+06 - - - -0.9164 - 2.174 0.341 - 136.6 1 2 0 -0.0012 11 0 0 0 7.74E+07 7.44E+07 - - - 4.5476 0.9959 221125_WJC_METTL3_EV_vs_WT_F06.11538.11538.3 0.000923 Nov-44 R.QTASIFKQPVTK.V "sp|Q9UBB5|MBD2_HUMAN,sp|O95983|MBD3_HUMAN,tr|A0A087X1H1|A0A087X1H1_HUMAN,tr|K7EIE8|K7EIE8_HUMAN,tr|A0A087WT34|A0A087WT34_HUMAN,tr|A0A0A0MTS6|A0A0A0MTS6_HUMAN,tr|J3KSA7|J3KSA7_HUMAN" 7 1346.7558 1.21 81137 11538 3 1346.759455 449.9259 Methyl-CpG-binding domain protein 2 OS=Homo sapiens OX=9606 GN=MBD2 PE=1 SV=1 10 2191.8 - 1.88E+06 - - - 2.7132 - 1.847 0.362 - 163.4 1 2 1 0.0037 12 0 0 0 2.91E+07 2.40E+07 - - - 4.2756 1 221125_WJC_METTL3_EV_vs_WT_F06.11539.11539.2 1.22E-06 13/24 K.DINAYNC[160.03]EEPTEK.L sp|P30041|PRDX6_HUMAN 1 1581.6617 0.96 81138 11539 2 1581.659842 791.8381 Peroxiredoxin-6 OS=Homo sapiens OX=9606 GN=PRDX6 PE=1 SV=3 4 2192 - 1.67E+06 - - - -1.176 - 2.615 0.64 - 541.6 1 2 0 -0.0019 13 0 0 0 4.16E+07 4.32E+07 - - - 6.2346 1 221125_WJC_METTL3_EV_vs_WT_F06.11540.11540.3 5.39E-07 16/52 R.VELHSTC[160.03]QTISVDR[166.11].Q sp|O00267|SPT5H_HUMAN 1 1653.802 0.6 81139 11540 3 1653.800083 552.2746 Transcription elongation factor SPT5 OS=Homo sapiens OX=9606 GN=SUPT5H PE=1 SV=1 5.32 2192.1 - 1.25E+06 - - - -1.1531 - 2.468 0.547 - 282.4 1 2 0 -0.0019 14 0 0 0 1.41E+07 2.34E+07 - - - 7.0388 0.9876 221125_WJC_METTL3_EV_vs_WT_F06.11543.11543.3 0.0991 Jul-40 K.AHVVPC[160.03]FDASK[136.11].V "sp|P21333|FLNA_HUMAN,tr|Q60FE5|Q60FE5_HUMAN" 2 1237.6005 1.3 81142 11543 3 1237.599355 413.5408 Filamin-A OS=Homo sapiens OX=9606 GN=FLNA PE=1 SV=4 6.78 2192.4 - 904647 - - - -0.9195 - 1.416 0.205 - 72.2 2 2 0 -0.0011 11 0 0 0 2.42E+07 1.87E+07 - - - 1.6741 0.9999 221125_WJC_METTL3_EV_vs_WT_F06.11550.11550.3 1.94E-05 Oct-40 K.AHVVPC[160.03]FDASK.V "sp|P21333|FLNA_HUMAN,tr|Q60FE5|Q60FE5_HUMAN" 2 1229.5863 1.04 81147 11550 3 1229.586541 410.8694 Filamin-A OS=Homo sapiens OX=9606 GN=FLNA PE=1 SV=4 6.78 2193.3 - 1.77E+06 - - - 0.2017 - 2.109 0.451 - 123.1 1 2 0 0.0002 11 0 0 0 2.71E+07 2.60E+07 - - - 5.688 0.9996 221125_WJC_METTL3_EV_vs_WT_F06.11553.11553.2 0.000253 20-Nov K.TSLMNQYVNKK.F "sp|P51149|RAB7A_HUMAN,tr|C9J592|C9J592_HUMAN,tr|C9J4V0|C9J4V0_HUMAN,tr|C9J7D1|C9J7D1_HUMAN,tr|A0A6Q8PH84|A0A6Q8PH84_HUMAN,tr|C9J8S3|C9J8S3_HUMAN,tr|C9IZZ0|C9IZZ0_HUMAN,tr|C9J4S4|C9J4S4_HUMAN,tr|A0A6Q8PG52|A0A6Q8PG52_HUMAN" 9 1324.6809 1.5 81150 11553 2 1324.683716 663.3477 Ras-related protein Rab-7a OS=Homo sapiens OX=9606 GN=RAB7A PE=1 SV=1 9.7 2193.5 - 752269 - - - 2.1099 - 1.926 0.465 - 519.4 1 2 0 0.0028 11 0 0 0 1.11E+07 7.40E+06 - - - 4.2477 1 221125_WJC_METTL3_EV_vs_WT_F06.11556.11556.2 2.67E-08 13/30 K.IC[160.03]TGQVPSAEDEPAPK.K sp|Q9BTC0|DIDO1_HUMAN 1 1697.7931 0.99 81153 11556 2 1697.792587 849.9038 Death-inducer obliterator 1 OS=Homo sapiens OX=9606 GN=DIDO1 PE=1 SV=5 4.14 2194 - 523532 - - - -0.2733 - 2.793 0.616 - 319.1 1 2 0 -0.0005 16 0 0 0 5.51E+06 5.56E+06 - - - 6.1158 1 221125_WJC_METTL3_EV_vs_WT_F06.11558.11558.2 2.74E-09 16/30 K.IC[160.03]TGQVPSAEDEPAPK[136.11].K sp|Q9BTC0|DIDO1_HUMAN 1 1705.8073 0.99 81155 11558 2 1705.805151 853.9109 Death-inducer obliterator 1 OS=Homo sapiens OX=9606 GN=DIDO1 PE=1 SV=5 4.14 2194.2 - 424587 - - - -1.2311 - 3.108 0.725 - 588.2 1 2 0 -0.0021 16 0 0 0 5.51E+06 5.56E+06 - - - 7.1831 0.7847 221125_WJC_METTL3_EV_vs_WT_F06.11559.11559.3 3.23 Aug-32 R.RRFPPYYMR.R "sp|P67809|YBOX1_HUMAN,tr|H0Y449|H0Y449_HUMAN,tr|C9J5V9|C9J5V9_HUMAN" 3 1284.655 3.11 81156 11559 3 1284.654958 429.2256 Y-box-binding protein 1 OS=Homo sapiens OX=9606 GN=YBX1 PE=1 SV=3 10.9 2194.3 - 271989 - - - -0.0179 - 1.279 0.135 - 68.9 1 2 1 0 9 0 0 0 2.03E+06 6.53E+05 - - - 0.7867 0.9999 221125_WJC_METTL3_EV_vs_WT_F06.11560.11560.2 4.47E-05 28-Nov R.AQEPESGLSEETQVK.C sp|P78527|PRKDC_HUMAN 1 1630.7686 1.9 81157 11560 2 1630.768351 816.3916 DNA-dependent protein kinase catalytic subunit OS=Homo sapiens OX=9606 GN=PRKDC PE=1 SV=3 4.09 2194.5 - 225450 - - - -0.1588 - 2.22 0.509 - 267 1 2 0 -0.0003 15 0 0 0 3.24E+06 1.71E+06 - - - 4.7611 1 221125_WJC_METTL3_EV_vs_WT_F06.11562.11562.3 7.44E-07 15/52 R.VTEFGGELHEDGGK.L "sp|Q9UFW8|CGBP1_HUMAN,tr|C9JUJ0|C9JUJ0_HUMAN" 2 1473.6736 0.95 81158 11562 3 1473.673324 492.2318 CGG triplet repeat-binding protein 1 OS=Homo sapiens OX=9606 GN=CGGBP1 PE=1 SV=2 4.4 2194.7 - 4.21E+06 - - - -0.1785 - 3.167 0.535 - 452.9 1 2 0 -0.0003 14 0 0 0 5.53E+07 5.81E+07 - - - 7.5682 0.9889 221125_WJC_METTL3_EV_vs_WT_F06.11566.11566.2 4.65E-07 26-Dec F.SASSLGGGFGGGSR.G sp|P35527|K1C9_HUMAN 1 1195.5582 61.99 81161 11566 2 1195.559269 598.7864 "Keratin, type I cytoskeletal 9 OS=Homo sapiens OX=9606 GN=KRT9 PE=1 SV=3" 9.47 2195.1 - 1.10E+06 - - - 0.9243 - 2.371 0.451 - 317.3 1 1 0 0.0011 14 0 0 0 1.79E+07 2.89E+05 - - - 4.5382 0.9788 221125_WJC_METTL3_EV_vs_WT_F06.11569.11569.3 0.156 Aug-40 R.LNQLKPGLQYK.L sp|Q12906|ILF3_HUMAN 1 1300.7503 1.08 81164 11569 3 1300.751746 434.5907 Interleukin enhancer-binding factor 3 OS=Homo sapiens OX=9606 GN=ILF3 PE=1 SV=3 9.7 2195.4 - 1.32E+06 - - - 1.0948 - 1.457 0.177 - 68.8 2 2 0 0.0014 11 0 0 0 1.02E+07 9.44E+06 - - - 1.4429 0.9999 221125_WJC_METTL3_EV_vs_WT_F06.11573.11573.3 0.00558 17/52 R.AELYKEPTNEELNR.L "sp|Q9H6R4|NOL6_HUMAN,tr|A0A0A0MRW6|A0A0A0MRW6_HUMAN" 2 1704.8319 1.14 81168 11573 3 1704.83184 569.2846 Nucleolar protein 6 OS=Homo sapiens OX=9606 GN=NOL6 PE=1 SV=2 4.49 2195.9 - 501722 - - - -0.0229 - 3.266 0.458 - 385.4 1 2 1 0 14 0 0 0 2.89E+07 2.54E+07 - - - 6.7916 0.9629 221125_WJC_METTL3_EV_vs_WT_F06.11575.11575.2 6.59E-07 22-Oct K.VSMNQLSQQK[136.11]PN.Q "sp|Q6P3W7|SCYL2_HUMAN,tr|A0A0U1RQQ9|A0A0U1RQQ9_HUMAN" 2 1380.6911 2.43 81170 11575 2 1380.695744 691.3528 SCY1-like protein 2 OS=Homo sapiens OX=9606 GN=SCYL2 PE=1 SV=1 8.72 2196.1 - 317239 - - - 3.3643 - 2.178 0.541 - 305.6 1 1 0 0.0046 12 0 0 0 1.11E+07 4.56E+06 - - - 5.0835 0.9998 221125_WJC_METTL3_EV_vs_WT_F06.11583.11583.3 7.67E-07 14/52 R.AELYK[136.11]EPTNEELNR[166.11].L "sp|Q9H6R4|NOL6_HUMAN,tr|A0A0A0MRW6|A0A0A0MRW6_HUMAN" 2 1722.8543 1.13 81176 11583 3 1722.857498 575.2921 Nucleolar protein 6 OS=Homo sapiens OX=9606 GN=NOL6 PE=1 SV=2 4.49 2197.1 - 2.44E+06 - - - 1.8278 - 2.869 0.516 - 254.8 1 2 1 0.0031 14 0 0 0 2.87E+07 2.54E+07 - - - 7.093 0.9986 221125_WJC_METTL3_EV_vs_WT_F06.11584.11584.2 0.481 14-Sep K.DIDIHEVR[166.11].L "sp|Q00839|HNRPU_HUMAN,tr|A0A1W2PQL0|A0A1W2PQL0_HUMAN,tr|A0A1W2PPL4|A0A1W2PPL4_HUMAN,tr|A0A1W2PQ74|A0A1W2PQ74_HUMAN,tr|Q5RI18|Q5RI18_HUMAN,tr|A0A1W2PP35|A0A1W2PP35_HUMAN,tr|A0A1W2PPS1|A0A1W2PPS1_HUMAN,tr|A0A1W2PRZ7|A0A1W2PRZ7_HUMAN,tr|A0A1W2PPH7|A0A1W2PPH7_HUMAN,tr|A0A1W2PP34|A0A1W2PP34_HUMAN,tr|A0A1X7SBS1|A0A1X7SBS1_HUMAN" 11 1005.5119 1.05 81177 11584 2 1005.513704 503.7632 Heterogeneous nuclear ribonucleoprotein U OS=Homo sapiens OX=9606 GN=HNRNPU PE=1 SV=6 4.54 2197.2 - 1.45E+06 - - - 1.815 - 1.742 0.273 - 340.9 1 2 0 0.0018 8 0 0 0 1.25E+07 1.19E+07 - - - 2.7308 1 221125_WJC_METTL3_EV_vs_WT_F06.11585.11585.3 4.54E-08 14/48 R.HYTFASGSPDNIK.Q "sp|O43660|PLRG1_HUMAN,tr|H0YAA2|H0YAA2_HUMAN" 2 1435.6732 0.98 81178 11585 3 1435.674358 479.565 Pleiotropic regulator 1 OS=Homo sapiens OX=9606 GN=PLRG1 PE=1 SV=1 6.74 2197.3 - 1.31E+06 - - - 0.8115 - 2.799 0.561 - 322.8 1 2 0 0.0012 13 0 0 0 1.05E+07 1.08E+07 - - - 7.5849 0.9994 221125_WJC_METTL3_EV_vs_WT_F06.11586.11586.3 0.000768 Nov-44 R.SQYEALVETNRR.E "sp|Q15323|K1H1_HUMAN,sp|O76009|KT33A_HUMAN,tr|A0A140TA62|A0A140TA62_HUMAN,tr|A0A140TA69|A0A140TA69_HUMAN" 4 1464.7321 106.27 81179 11586 3 1464.733986 489.2513 "Keratin, type I cuticular Ha1 OS=Homo sapiens OX=9606 GN=KRT31 PE=1 SV=3" 5.86 2197.4 - 1.28E+06 - - - 1.2842 - 1.904 0.314 - 192.1 1 2 0 0.0019 12 0 0 0 1.29E+07 1.22E+05 - - - 3.8252 0.9999 221125_WJC_METTL3_EV_vs_WT_F06.11587.11587.3 1.54E-05 Oct-44 K.FEHC[160.03]NFNDVTTR.L "sp|P13987|CD59_HUMAN,tr|E9PNW4|E9PNW4_HUMAN,tr|A0A2U3TZL5|A0A2U3TZL5_HUMAN" 3 1538.6572 1.87 81180 11587 3 1538.66099 513.893 CD59 glycoprotein OS=Homo sapiens OX=9606 GN=CD59 PE=1 SV=1 5.32 2197.4 - 1.08E+06 - - - 2.4463 - 2.098 0.554 - 142.4 1 2 0 0.0038 12 0 0 0 1.28E+07 6.86E+06 - - - 6.7694 0.9991 221125_WJC_METTL3_EV_vs_WT_F06.11589.11589.2 4.41E-07 20-Oct K.AHVVPC[160.03]FDASK.V "sp|P21333|FLNA_HUMAN,tr|Q60FE5|Q60FE5_HUMAN" 2 1229.5863 1.33 81182 11589 2 1229.589783 615.8004 Filamin-A OS=Homo sapiens OX=9606 GN=FLNA PE=1 SV=4 6.78 2197.7 - 851056 - - - 2.8384 - 1.842 0.433 - 293.8 1 2 0 0.0035 11 0 0 0 1.09E+07 8.22E+06 - - - 3.8905 0.9995 221125_WJC_METTL3_EV_vs_WT_F06.11590.11590.3 0.000544 Nov-60 R.APC[160.03]AGPSREEELAAVR.E sp|Q9BU76|MMTA2_HUMAN 1 1711.8312 15.12 81183 11590 3 1711.833466 571.6177 Multiple myeloma tumor-associated protein 2 OS=Homo sapiens OX=9606 GN=MMTAG2 PE=1 SV=1 4.79 2197.8 - 674991 - - - 1.3424 - 2.125 0.439 - 122 1 2 1 0.0023 16 0 0 0 6.12E+06 4.05E+05 - - - 5.3679 0.9999 221125_WJC_METTL3_EV_vs_WT_F06.11591.11591.3 4.19E-06 Sep-44 K.FEHC[160.03]NFNDVTTR[166.11].L "sp|P13987|CD59_HUMAN,tr|E9PNW4|E9PNW4_HUMAN,tr|A0A2U3TZL5|A0A2U3TZL5_HUMAN" 3 1548.6655 1.87 81184 11591 3 1548.668644 517.2291 CD59 glycoprotein OS=Homo sapiens OX=9606 GN=CD59 PE=1 SV=1 5.32 2197.9 - 665311 - - - 2.0327 - 1.7 0.53 - 113.4 1 2 0 0.0031 12 0 0 0 1.28E+07 6.86E+06 - - - 5.9189 0.9969 221125_WJC_METTL3_EV_vs_WT_F06.11592.11592.3 0.399 Sep-32 R.QNFHMEQLK.Y sp|Q92922|SMRC1_HUMAN 1 1173.5601 1.88 81185 11592 3 1173.562076 392.194 SWI\SNF complex subunit SMARCC1 OS=Homo sapiens OX=9606 GN=SMARCC1 PE=1 SV=3 6.75 2198 - 542617 - - - 1.7025 - 1.537 0.271 - 120.1 1 2 0 0.002 9 0 0 0 9.82E+06 5.22E+06 - - - 2.8563 0.9999 221125_WJC_METTL3_EV_vs_WT_F06.11593.11593.3 3.49E-08 14/60 R.LSGAAPAHSAADPWEK.E "sp|Q9BSJ6|PIMRE_HUMAN,tr|I3L156|I3L156_HUMAN,tr|I3L419|I3L419_HUMAN,tr|I3L2R2|I3L2R2_HUMAN" 4 1606.774 0.44 81186 11593 3 1606.778912 536.5986 Protein PIMREG OS=Homo sapiens OX=9606 GN=PIMREG PE=1 SV=1 5.32 2198.1 - 522409 - - - 3.0757 - 2.684 0.497 - 212.9 1 2 0 0.0049 16 0 0 0 1.03E+07 2.32E+07 - - - 6.613 0.9995 221125_WJC_METTL3_EV_vs_WT_F06.11594.11594.2 1.43E-05 20-Aug K.DMAQSIYR[166.11]PSK[136.11].N "sp|Q13573|SNW1_HUMAN,tr|G3V4X8|G3V4X8_HUMAN,tr|G3V3A4|G3V3A4_HUMAN" 3 1312.6564 0.38 81187 11594 2 1312.658999 657.3355 SNW domain-containing protein 1 OS=Homo sapiens OX=9606 GN=SNW1 PE=1 SV=1 8.59 2198.3 - 390074 - - - 1.9487 - 1.769 0.461 - 194.4 1 2 0 0.0026 11 0 0 0 7.38E+06 1.97E+07 - - - 3.9882 0.9991 221125_WJC_METTL3_EV_vs_WT_F06.11595.11595.3 0.00165 Sep-32 R.QNFHMEQLK[136.11].Y sp|Q92922|SMRC1_HUMAN 1 1181.5743 1.89 81188 11595 3 1181.576116 394.8654 SWI\SNF complex subunit SMARCC1 OS=Homo sapiens OX=9606 GN=SMARCC1 PE=1 SV=3 6.75 2198.4 - 511426 - - - 1.5556 - 1.698 0.314 - 105.1 1 2 0 0.0018 9 0 0 0 9.70E+06 5.13E+06 - - - 3.6359 0.964 221125_WJC_METTL3_EV_vs_WT_F06.11596.11596.2 7.63E-08 26-Dec V.SVLSSGTQAVSGSK.D "sp|Q9BQA1|MEP50_HUMAN,tr|H0Y711|H0Y711_HUMAN" 2 1306.6729 2.87 81189 11596 2 1306.677445 654.3437 Methylosome protein 50 OS=Homo sapiens OX=9606 GN=WDR77 PE=1 SV=1 8.47 2198.5 - 345596 - - - 3.5097 - 2.535 0.542 - 385.5 1 1 0 0.0046 14 0 0 0 1.41E+07 4.92E+06 - - - 5.377 0.8505 221125_WJC_METTL3_EV_vs_WT_F06.11598.11598.3 0.0441 Jul-48 K.DINAYNC[160.03]EEPTEK.L sp|P30041|PRDX6_HUMAN 1 1581.6617 1.97 81191 11598 3 1581.674707 528.2278 Peroxiredoxin-6 OS=Homo sapiens OX=9606 GN=PRDX6 PE=1 SV=3 4 2198.8 - 315195 - - - 8.2224 - 1.502 0.291 - 40.8 1 2 0 0.013 13 0 0 0 2.12E+06 1.08E+06 - - - 2.8837 0.9963 221125_WJC_METTL3_EV_vs_WT_F06.11600.11600.3 5.57E-05 13/60 K.KPGLTPSPSATTPLTK.T sp|Q9P2B4|CT2NL_HUMAN 1 1594.893 1.78 81193 11600 3 1594.902175 532.6383 CTTNBP2 N-terminal-like protein OS=Homo sapiens OX=9606 GN=CTTNBP2NL PE=1 SV=2 10 2199.1 - 281481 - - - 5.7383 - 2.181 0.393 - 197.9 1 2 0 0.0092 16 0 0 0 5.28E+06 2.97E+06 - - - 4.9198 1 221125_WJC_METTL3_EV_vs_WT_F06.11605.11605.3 1.48E-08 16/44 R.DSLTGSSDLYK[136.11]R[166.11].T "sp|Q14671|PUM1_HUMAN,tr|Q5T1Z8|Q5T1Z8_HUMAN,tr|H0YDK8|H0YDK8_HUMAN,tr|Q5T1Z4|Q5T1Z4_HUMAN,tr|E9PR38|E9PR38_HUMAN" 5 1358.6797 2.19 81196 11605 3 1358.681513 453.9005 Pumilio homolog 1 OS=Homo sapiens OX=9606 GN=PUM1 PE=1 SV=3 5.96 2199.6 - 4.21E+06 - - - 1.3498 - 3.644 0.539 - 744.6 1 2 0 0.0018 12 0 0 0 1.41E+08 6.45E+07 - - - 8.133 0.999 221125_WJC_METTL3_EV_vs_WT_F06.11607.11607.2 0.0505 14-Sep K.DIDIHEVR.L "sp|Q00839|HNRPU_HUMAN,tr|A0A1W2PQL0|A0A1W2PQL0_HUMAN,tr|A0A1W2PPL4|A0A1W2PPL4_HUMAN,tr|A0A1W2PQ74|A0A1W2PQ74_HUMAN,tr|Q5RI18|Q5RI18_HUMAN,tr|A0A1W2PP35|A0A1W2PP35_HUMAN,tr|A0A1W2PPS1|A0A1W2PPS1_HUMAN,tr|A0A1W2PRZ7|A0A1W2PRZ7_HUMAN,tr|A0A1W2PPH7|A0A1W2PPH7_HUMAN,tr|A0A1W2PP34|A0A1W2PP34_HUMAN,tr|A0A1X7SBS1|A0A1X7SBS1_HUMAN" 11 995.5036 1.05 81198 11607 2 995.505085 498.7591 Heterogeneous nuclear ribonucleoprotein U OS=Homo sapiens OX=9606 GN=HNRNPU PE=1 SV=6 4.54 2199.8 - 1.60E+06 - - - 1.4827 - 1.73 0.299 - 331.1 1 2 0 0.0015 8 0 0 0 1.25E+07 1.19E+07 - - - 2.9021 0.9999 221125_WJC_METTL3_EV_vs_WT_F06.11610.11610.2 0.000128 22-Nov R.DSLTGSSDLYKR.T "sp|Q14671|PUM1_HUMAN,tr|Q5T1Z8|Q5T1Z8_HUMAN,tr|H0YDK8|H0YDK8_HUMAN,tr|Q5T1Z4|Q5T1Z4_HUMAN,tr|E9PR38|E9PR38_HUMAN" 5 1340.6572 2.24 81201 11610 2 1340.65783 671.3359 Pumilio homolog 1 OS=Homo sapiens OX=9606 GN=PUM1 PE=1 SV=3 5.96 2200 - 987687 - - - 0.4632 - 2.298 0.503 - 400.8 1 2 0 0.0006 12 0 0 0 2.71E+07 1.21E+07 - - - 4.9452 1 221125_WJC_METTL3_EV_vs_WT_F06.11612.11612.3 0.00113 Dec-40 R.DGFVQNVHTPR[166.11].V sp|Q10570|CPSF1_HUMAN 1 1278.6345 -1 81203 11612 3 1278.636055 427.2188 Cleavage and polyadenylation specificity factor subunit 1 OS=Homo sapiens OX=9606 GN=CPSF1 PE=1 SV=2 6.74 2200.2 - 744594 - - - 1.2521 - 2.699 0.456 - 152.2 1 2 0 0.0016 11 0 0 0 0.00E+00 0.00E+00 - - - 6.4441 0.9999 221125_WJC_METTL3_EV_vs_WT_F06.11614.11614.2 0.000131 14/22 R.DSLTGSSDLYK[136.11]R[166.11].T "sp|Q14671|PUM1_HUMAN,tr|Q5T1Z8|Q5T1Z8_HUMAN,tr|H0YDK8|H0YDK8_HUMAN,tr|Q5T1Z4|Q5T1Z4_HUMAN,tr|E9PR38|E9PR38_HUMAN" 5 1358.6797 2.24 81205 11614 2 1358.67989 680.3471 Pumilio homolog 1 OS=Homo sapiens OX=9606 GN=PUM1 PE=1 SV=3 5.96 2200.4 - 549411 - - - 0.1553 - 2.741 0.484 - 819.1 1 2 0 0.0002 12 0 0 0 2.71E+07 1.21E+07 - - - 5.2688 0.9208 221125_WJC_METTL3_EV_vs_WT_F06.11615.11615.3 0.0952 Sep-44 R.LRHEILLSQSVR.Q sp|P54886|P5CS_HUMAN 1 1449.8416 0.85 81206 11615 3 1449.844262 484.2878 Delta-1-pyrroline-5-carboxylate synthase OS=Homo sapiens OX=9606 GN=ALDH18A1 PE=1 SV=2 9.61 2200.5 - 685524 - - - 1.8388 - 1.621 0.17 - 87.7 1 2 1 0.0027 12 0 0 0 5.48E+06 6.42E+06 - - - 1.7735 1 221125_WJC_METTL3_EV_vs_WT_F06.11618.11618.2 3.36E-07 14/24 R.HYTFASGSPDNIK[136.11].Q "sp|O43660|PLRG1_HUMAN,tr|H0YAA2|H0YAA2_HUMAN" 2 1443.6874 0.33 81209 11618 2 1443.688897 722.851 Pleiotropic regulator 1 OS=Homo sapiens OX=9606 GN=PLRG1 PE=1 SV=1 6.74 2200.8 - 513202 - - - 1.0418 - 2.696 0.606 - 452.7 1 2 0 0.0015 13 0 0 0 4.28E+06 1.28E+07 - - - 6.0618 0.975 221125_WJC_METTL3_EV_vs_WT_F06.11621.11621.2 0.0232 26-Dec V.SVLSSGTQAVSGSK[136.11].D "sp|Q9BQA1|MEP50_HUMAN,tr|H0Y711|H0Y711_HUMAN" 2 1314.6871 4.54 81212 11621 2 1314.690738 658.3508 Methylosome protein 50 OS=Homo sapiens OX=9606 GN=WDR77 PE=1 SV=1 8.47 2201.2 - 378136 - - - 2.7984 - 2.875 0.459 - 351.5 1 1 0 0.0037 14 0 0 0 3.08E+07 6.78E+06 - - - 5.0801 0.9994 221125_WJC_METTL3_EV_vs_WT_F06.11622.11622.2 0.00664 20-Aug K.AHVVPC[160.03]FDASK[136.11].V "sp|P21333|FLNA_HUMAN,tr|Q60FE5|Q60FE5_HUMAN" 2 1237.6005 1.49 81213 11622 2 1237.600015 619.8075 Filamin-A OS=Homo sapiens OX=9606 GN=FLNA PE=1 SV=4 6.78 2201.3 - 352870 - - - -0.3862 - 1.471 0.383 - 193.7 1 2 0 -0.0005 11 0 0 0 9.46E+06 6.34E+06 - - - 2.9138 0.9981 221125_WJC_METTL3_EV_vs_WT_F06.11623.11623.3 0.0185 Nov-40 R.GSRPLSSFVQK.A sp|A8CG34|P121C_HUMAN 1 1204.6564 1.25 81214 11623 3 1204.657592 402.5594 Nuclear envelope pore membrane protein POM 121C OS=Homo sapiens OX=9606 GN=POM121C PE=1 SV=3 11 2201.4 - 333295 - - - 0.9721 - 1.757 0.251 - 161.4 1 2 0 0.0012 11 0 0 0 5.50E+06 4.41E+06 - - - 2.9392 1 221125_WJC_METTL3_EV_vs_WT_F06.11624.11624.2 2.95E-06 18/26 K.VSEFNVSSEGSGEK.L sp|Q9BVJ6|UT14A_HUMAN 1 1454.6525 1.74 81215 11624 2 1454.653756 728.3335 U3 small nucleolar RNA-associated protein 14 homolog A OS=Homo sapiens OX=9606 GN=UTP14A PE=1 SV=1 4.25 2201.6 - 316890 - - - 0.8511 - 3.341 0.57 - 1023.6 1 2 0 0.0012 14 0 0 0 3.71E+07 2.14E+07 - - - 6.2777 0.9998 221125_WJC_METTL3_EV_vs_WT_F06.11628.11628.3 1.53E-05 Dec-48 K.QK[136.11]EVITAQDTVIK[136.11].A sp|O95347|SMC2_HUMAN 1 1487.853 54.85 81218 11628 3 1487.854651 496.9583 Structural maintenance of chromosomes protein 2 OS=Homo sapiens OX=9606 GN=SMC2 PE=1 SV=2 6.07 2202.1 - 1.82E+06 - - - 1.1036 - 2.426 0.457 - 327 1 2 1 0.0016 13 0 0 0 5.97E+08 1.09E+07 - - - 6.0375 1 221125_WJC_METTL3_EV_vs_WT_F06.11630.11630.3 0.00154 17/60 R.LSGAAPAHSAADPWEK[136.11].E "sp|Q9BSJ6|PIMRE_HUMAN,tr|I3L156|I3L156_HUMAN,tr|I3L419|I3L419_HUMAN,tr|I3L2R2|I3L2R2_HUMAN" 4 1614.7882 0.89 81220 11630 3 1614.7897 539.27 Protein PIMREG OS=Homo sapiens OX=9606 GN=PIMREG PE=1 SV=1 5.32 2202.2 - 1.36E+06 - - - 0.9475 - 3.151 0.438 - 260.5 1 2 0 0.0015 16 0 0 0 9.83E+06 1.11E+07 - - - 6.3677 0.9974 221125_WJC_METTL3_EV_vs_WT_F06.11632.11632.3 0.00851 13/40 R.DGFVQNVHTPR.V sp|Q10570|CPSF1_HUMAN 1 1268.6262 -1 81222 11632 3 1269.630384 423.8827 Cleavage and polyadenylation specificity factor subunit 1 OS=Homo sapiens OX=9606 GN=CPSF1 PE=1 SV=2 6.74 2202.4 - 698524 - - - 791.5649 - 2.425 0.403 - 186.5 1 2 0 1.0042 11 0 0 0 0.00E+00 0.00E+00 - - - 5.2714 0.9999 221125_WJC_METTL3_EV_vs_WT_F06.11634.11634.2 6.04E-10 13/22 K.NNGNSTSLPLSR.K "sp|Q01804|OTUD4_HUMAN,tr|D6RI06|D6RI06_HUMAN" 2 1258.6266 1.5 81224 11634 2 1258.626742 630.3206 OTU domain-containing protein 4 OS=Homo sapiens OX=9606 GN=OTUD4 PE=1 SV=4 9.75 2202.6 - 651863 - - - 0.1303 - 2.776 0.449 - 715.4 1 2 0 0.0002 12 0 0 0 2.69E+07 1.79E+07 - - - 5.0437 0.9999 221125_WJC_METTL3_EV_vs_WT_F06.11636.11636.2 8.60E-07 24-Nov R.HYTFASGSPDNIK.Q "sp|O43660|PLRG1_HUMAN,tr|H0YAA2|H0YAA2_HUMAN" 2 1435.6732 0.43 81226 11636 2 1435.674522 718.8439 Pleiotropic regulator 1 OS=Homo sapiens OX=9606 GN=PLRG1 PE=1 SV=1 6.74 2202.9 - 371651 - - - 0.9257 - 2.334 0.569 - 328.3 1 2 0 0.0013 13 0 0 0 3.71E+06 8.58E+06 - - - 5.4186 0.9963 221125_WJC_METTL3_EV_vs_WT_F06.11638.11638.3 0.0107 Nov-48 K.TFDQLTPEESKER.L sp|O43852|CALU_HUMAN 1 1578.7526 0.47 81228 11638 3 1578.756198 527.2581 Calumenin OS=Homo sapiens OX=9606 GN=CALU PE=1 SV=2 4.41 2203.1 - 337638 - - - 2.3006 - 2.069 0.323 - 131.7 1 2 1 0.0036 13 0 0 0 9.85E+06 2.10E+07 - - - 4.1114 0.9995 221125_WJC_METTL3_EV_vs_WT_F06.11639.11639.2 2.28E-05 30-Sep R.YTTPEDATPEPGEDPR.V "sp|P63092|GNAS2_HUMAN,sp|Q5JWF2|GNAS1_HUMAN,tr|A0A590UJ22|A0A590UJ22_HUMAN,tr|A0A590UJQ2|A0A590UJQ2_HUMAN,tr|A0A590UJR6|A0A590UJR6_HUMAN,tr|A0A590UJS2|A0A590UJS2_HUMAN,tr|A0A590UK28|A0A590UK28_HUMAN,tr|A0A590UKB4|A0A590UKB4_HUMAN,tr|A0A590UJF0|A0A590UJF0_HUMAN,tr|Q5JWE9|Q5JWE9_HUMAN,tr|A0A590UJA5|A0A590UJA5_HUMAN,tr|A0A0A0MR13|A0A0A0MR13_HUMAN,tr|B0AZR9|B0AZR9_HUMAN,tr|A0A590UJI6|A0A590UJI6_HUMAN,tr|A0A590UJQ9|A0A590UJQ9_HUMAN,tr|A0A590UJ58|A0A590UJ58_HUMAN,tr|A0A590UJB7|A0A590UJB7_HUMAN,tr|A0A590UJJ0|A0A590UJJ0_HUMAN,tr|A0A7I2V5R6|A0A7I2V5R6_HUMAN,tr|A0A590UKA1|A0A590UKA1_HUMAN,tr|A0A804HIH4|A0A804HIH4_HUMAN,tr|A0A590UJY2|A0A590UJY2_HUMAN,tr|A0A590UJB0|A0A590UJB0_HUMAN,tr|A0A590UKA4|A0A590UKA4_HUMAN,tr|A0A590UJY8|A0A590UJY8_HUMAN,tr|A0A590UJG5|A0A590UJG5_HUMAN,tr|S4R3V9|S4R3V9_HUMAN,tr|A0A590UKA9|A0A590UKA9_HUMAN" 28 1773.7693 1.24 81229 11639 2 1773.77335 887.8919 Guanine nucleotide-binding protein G(s) subunit alpha isoforms short OS=Homo sapiens OX=9606 GN=GNAS PE=1 SV=1 3.83 2203.3 - 336791 - - - 2.2618 - 1.625 0.541 - 105.4 1 2 0 0.004 16 0 0 0 6.40E+06 5.18E+06 - - - 4.2292 1 221125_WJC_METTL3_EV_vs_WT_F06.11641.11641.2 2.16E-09 14/26 R.TPDTSTYC[160.03]YETAEK.L sp|P46821|MAP1B_HUMAN 1 1664.6876 2.29 81231 11641 2 1664.683849 833.3511 Microtubule-associated protein 1B OS=Homo sapiens OX=9606 GN=MAP1B PE=1 SV=2 4.14 2203.5 - 158012 - - - -2.2431 - 3.163 0.698 - 876.7 1 2 0 -0.0037 14 0 0 0 1.58E+06 6.89E+05 - - - 7.0849 0.9788 221125_WJC_METTL3_EV_vs_WT_F06.11642.11642.2 9.71E-06 24-Sep K.QK[136.11]EVITAQDTVIK[136.11].A sp|O95347|SMC2_HUMAN 1 1487.853 -1 81232 11642 2 1487.859786 744.9338 Structural maintenance of chromosomes protein 2 OS=Homo sapiens OX=9606 GN=SMC2 PE=1 SV=2 6.07 2203.7 - 156674 - - - 4.5549 - 2.06 0.512 - 254.7 1 2 1 0.0068 13 0 0 0 0.00E+00 0.00E+00 - - - 4.6754 1 221125_WJC_METTL3_EV_vs_WT_F06.11646.11646.2 2.10E-10 17/26 K.VSEFNVSSEGSGEK[136.11].L sp|Q9BVJ6|UT14A_HUMAN 1 1462.6667 1.79 81234 11646 2 1462.668155 732.3406 U3 small nucleolar RNA-associated protein 14 homolog A OS=Homo sapiens OX=9606 GN=UTP14A PE=1 SV=1 4.25 2204.1 - 1.68E+06 - - - 0.9825 - 3.263 0.659 - 913.8 1 2 0 0.0014 14 0 0 0 3.88E+07 2.16E+07 - - - 6.8757 0.9979 221125_WJC_METTL3_EV_vs_WT_F06.11650.11650.3 0.0117 Dec-48 K.TFDQLTPEESK[136.11]ER[166.11].L sp|O43852|CALU_HUMAN 1 1596.775 0.34 81238 11650 3 1596.77572 533.2656 Calumenin OS=Homo sapiens OX=9606 GN=CALU PE=1 SV=2 4.41 2204.5 - 844312 - - - 0.4284 - 2.025 0.309 - 163.1 1 2 1 0.0007 13 0 0 0 1.06E+07 3.14E+07 - - - 3.8979 0.9999 221125_WJC_METTL3_EV_vs_WT_F06.11653.11653.2 2.33E-06 30-Sep R.YTTPEDATPEPGEDPR[166.11].V "sp|P63092|GNAS2_HUMAN,sp|Q5JWF2|GNAS1_HUMAN,tr|A0A590UJ22|A0A590UJ22_HUMAN,tr|A0A590UJQ2|A0A590UJQ2_HUMAN,tr|A0A590UJR6|A0A590UJR6_HUMAN,tr|A0A590UJS2|A0A590UJS2_HUMAN,tr|A0A590UK28|A0A590UK28_HUMAN,tr|A0A590UKB4|A0A590UKB4_HUMAN,tr|A0A590UJF0|A0A590UJF0_HUMAN,tr|Q5JWE9|Q5JWE9_HUMAN,tr|A0A590UJA5|A0A590UJA5_HUMAN,tr|A0A0A0MR13|A0A0A0MR13_HUMAN,tr|B0AZR9|B0AZR9_HUMAN,tr|A0A590UJI6|A0A590UJI6_HUMAN,tr|A0A590UJQ9|A0A590UJQ9_HUMAN,tr|A0A590UJ58|A0A590UJ58_HUMAN,tr|A0A590UJB7|A0A590UJB7_HUMAN,tr|A0A590UJJ0|A0A590UJJ0_HUMAN,tr|A0A7I2V5R6|A0A7I2V5R6_HUMAN,tr|A0A590UKA1|A0A590UKA1_HUMAN,tr|A0A804HIH4|A0A804HIH4_HUMAN,tr|A0A590UJY2|A0A590UJY2_HUMAN,tr|A0A590UJB0|A0A590UJB0_HUMAN,tr|A0A590UKA4|A0A590UKA4_HUMAN,tr|A0A590UJY8|A0A590UJY8_HUMAN,tr|A0A590UJG5|A0A590UJG5_HUMAN,tr|S4R3V9|S4R3V9_HUMAN,tr|A0A590UKA9|A0A590UKA9_HUMAN" 28 1783.7776 1.03 81241 11653 2 1783.780156 892.8961 Guanine nucleotide-binding protein G(s) subunit alpha isoforms short OS=Homo sapiens OX=9606 GN=GNAS PE=1 SV=1 3.83 2204.8 - 511820 - - - 1.4284 - 1.832 0.692 - 110 1 2 0 0.0025 16 0 0 0 3.10E+06 3.01E+06 - - - 5.6397 0.9438 221125_WJC_METTL3_EV_vs_WT_F06.11655.11655.3 0.0382 Oct-40 R.GSR[166.11]PLSSFVQK[136.11].A sp|A8CG34|P121C_HUMAN 1 1222.6789 1.36 81243 11655 3 1222.683523 408.5669 Nuclear envelope pore membrane protein POM 121C OS=Homo sapiens OX=9606 GN=POM121C PE=1 SV=3 11 2205.1 - 442036 - - - 3.7884 - 1.452 0.206 - 103.8 1 2 0 0.0046 11 0 0 0 3.86E+06 2.85E+06 - - - 1.8949 0.9924 221125_WJC_METTL3_EV_vs_WT_F06.11659.11659.3 0.114 Sep-36 K.DQHSFELDEK[136.11].A "sp|Q6DD88|ATLA3_HUMAN,tr|F5GWF8|F5GWF8_HUMAN,tr|F5H6I7|F5H6I7_HUMAN" 3 1254.5608 1.08 81247 11659 3 1254.563893 419.1942 Atlastin-3 OS=Homo sapiens OX=9606 GN=ATL3 PE=1 SV=1 4.31 2205.6 - 416693 - - - 2.4686 - 1.506 0.256 - 133.7 1 2 0 0.0031 10 0 0 0 8.61E+06 7.98E+06 - - - 2.5891 0.9999 221125_WJC_METTL3_EV_vs_WT_F06.11661.11661.4 0.000167 13/72 M.PAYFQRPENALKR.A sp|Q14152|EIF3A_HUMAN 1 1588.8474 1.46 81249 11661 4 1588.847407 398.2191 Eukaryotic translation initiation factor 3 subunit A OS=Homo sapiens OX=9606 GN=EIF3A PE=1 SV=1 10 2205.8 - 368444 - - - -0.0019 - 2.35 0.437 - 108.7 1 2 0 0 13 0 0 0 3.32E+06 2.27E+06 - - - 3.3464 0.981 221125_WJC_METTL3_EV_vs_WT_F06.11665.11665.3 0.0104 14/56 F.SVNGSGHFC[160.03]GVAEMK[136.11].S "sp|Q9Y5A9|YTHD2_HUMAN,sp|Q9BYJ9|YTHD1_HUMAN,sp|Q7Z739|YTHD3_HUMAN,tr|A0A087X0Q1|A0A087X0Q1_HUMAN,tr|A0A024R7W5|A0A024R7W5_HUMAN,tr|A0A087WY31|A0A087WY31_HUMAN" 6 1586.7061 0.99 81253 11665 3 1586.711783 529.9093 YTH domain-containing family protein 2 OS=Homo sapiens OX=9606 GN=YTHDF2 PE=1 SV=2 6.46 2206.4 - 251480 - - - 3.5835 - 2.37 0.508 - 132.5 1 1 0 0.0057 15 0 0 0 1.65E+07 1.67E+07 - - - 6.4537 1 221125_WJC_METTL3_EV_vs_WT_F06.11669.11669.3 0.00103 17/52 R.YANNSNYKNDVMIR.K "sp|Q96A72|MGN2_HUMAN,sp|P61326|MGN_HUMAN,tr|F5H6N1|F5H6N1_HUMAN" 3 1700.7941 0.94 81256 11669 3 1700.795378 567.9386 Protein mago nashi homolog 2 OS=Homo sapiens OX=9606 GN=MAGOHB PE=1 SV=1 8.5 2206.8 - 2.35E+06 - - - 0.7785 - 3.24 0.594 - 247.4 1 2 1 0.0013 14 0 0 0 1.42E+07 1.51E+07 - - - 8.2863 1 221125_WJC_METTL3_EV_vs_WT_F06.11671.11671.3 5.07E-06 15/48 K.VADWTGATYQDKR.Y "sp|O15371|EIF3D_HUMAN,tr|B0QYA8|B0QYA8_HUMAN,tr|B0QYA6|B0QYA6_HUMAN,tr|B0QYA5|B0QYA5_HUMAN" 4 1509.7212 1.01 81258 11671 3 1509.719798 504.2477 Eukaryotic translation initiation factor 3 subunit D OS=Homo sapiens OX=9606 GN=EIF3D PE=1 SV=1 5.93 2206.9 - 1.72E+06 - - - -0.9326 - 3.407 0.54 - 440.2 1 2 0 -0.0014 13 0 0 0 2.40E+08 2.38E+08 - - - 7.8837 0.9999 221125_WJC_METTL3_EV_vs_WT_F06.11672.11672.3 5.28E-09 14/52 R.YANNSNYK[136.11]NDVMIR[166.11].K "sp|Q96A72|MGN2_HUMAN,sp|P61326|MGN_HUMAN,tr|F5H6N1|F5H6N1_HUMAN" 3 1718.8165 0.91 81259 11672 3 1718.818942 573.9461 Protein mago nashi homolog 2 OS=Homo sapiens OX=9606 GN=MAGOHB PE=1 SV=1 8.5 2207 - 1.69E+06 - - - 1.4068 - 2.696 0.588 - 133.4 1 2 1 0.0024 14 0 0 0 1.42E+07 1.57E+07 - - - 7.7306 0.9998 221125_WJC_METTL3_EV_vs_WT_F06.11675.11675.3 0.0648 Sep-36 K.DQHSFELDEK.A "sp|Q6DD88|ATLA3_HUMAN,tr|F5GWF8|F5GWF8_HUMAN,tr|F5H6I7|F5H6I7_HUMAN" 3 1246.5466 1.11 81262 11675 3 1246.547393 416.5228 Atlastin-3 OS=Homo sapiens OX=9606 GN=ATL3 PE=1 SV=1 4.31 2207.2 - 956145 - - - 0.6394 - 1.755 0.381 - 120 1 2 0 0.0008 10 0 0 0 8.61E+06 7.76E+06 - - - 4.4302 0.9999 221125_WJC_METTL3_EV_vs_WT_F06.11683.11683.2 6.58E-10 15/28 R.VDSQASITQDSDSIK[136.11].K "sp|Q6KC79|NIPBL_HUMAN,tr|A0A590UJS4|A0A590UJS4_HUMAN" 2 1600.7672 1.87 81270 11683 2 1600.766449 801.3909 Nipped-B-like protein OS=Homo sapiens OX=9606 GN=NIPBL PE=1 SV=2 3.93 2208.2 - 487569 - - - -0.4442 - 3.307 0.498 - 766.9 1 2 0 -0.0007 15 0 0 0 9.70E+06 5.19E+06 - - - 5.6595 1 221125_WJC_METTL3_EV_vs_WT_F06.11684.11684.3 3.94E-08 14/60 K.IATGHGQQGVTQVVLK.G "sp|P51610|HCFC1_HUMAN,tr|A6NEM2|A6NEM2_HUMAN" 2 1634.9104 0.54 81271 11684 3 1634.90775 545.9774 Host cell factor 1 OS=Homo sapiens OX=9606 GN=HCFC1 PE=1 SV=2 8.76 2208.4 - 411208 - - - -1.6233 - 2.937 0.525 - 229.8 1 2 0 -0.0027 16 0 0 0 2.53E+07 4.68E+07 - - - 7.1569 0.9991 221125_WJC_METTL3_EV_vs_WT_F06.11685.11685.3 1.41E-05 Dec-56 K.LGETYK[136.11]DHENIVIAK[136.11].M "sp|P07237|PDIA1_HUMAN,tr|A0A7P0TA97|A0A7P0TA97_HUMAN,tr|A0A7P0T8C0|A0A7P0T8C0_HUMAN,tr|H7BZ94|H7BZ94_HUMAN,tr|B3KTQ9|B3KTQ9_HUMAN,tr|A0A7P0TA71|A0A7P0TA71_HUMAN,tr|I3L4M2|I3L4M2_HUMAN,tr|A0A7P0T9K9|A0A7P0T9K9_HUMAN,tr|H0Y3Z3|H0Y3Z3_HUMAN,tr|A0A7P0TA35|A0A7P0TA35_HUMAN,tr|A0A7P0TB26|A0A7P0TB26_HUMAN,tr|A0A7P0T9U6|A0A7P0T9U6_HUMAN,tr|I3L0S0|I3L0S0_HUMAN,tr|I3L3P5|I3L3P5_HUMAN,tr|A0A7P0T8J3|A0A7P0T8J3_HUMAN,tr|A0A7P0T8X1|A0A7P0T8X1_HUMAN" 16 1744.9331 1.49 81272 11685 3 1744.934988 582.6516 Protein disulfide-isomerase OS=Homo sapiens OX=9606 GN=P4HB PE=1 SV=3 5.45 2208.5 - 389258 - - - 1.1106 - 2.246 0.361 - 127.9 1 2 1 0.0019 15 0 0 0 5.50E+06 3.70E+06 - - - 4.6756 1 221125_WJC_METTL3_EV_vs_WT_F06.11688.11688.3 9.02E-07 16/44 R.DSLTGSSDLYKR.T "sp|Q14671|PUM1_HUMAN,tr|Q5T1Z8|Q5T1Z8_HUMAN,tr|H0YDK8|H0YDK8_HUMAN,tr|Q5T1Z4|Q5T1Z4_HUMAN,tr|E9PR38|E9PR38_HUMAN" 5 1340.6572 2.17 81274 11688 3 1340.658303 447.893 Pumilio homolog 1 OS=Homo sapiens OX=9606 GN=PUM1 PE=1 SV=3 5.96 2208.8 - 8.97E+06 - - - 0.816 - 3.38 0.506 - 708.1 1 2 0 0.0011 12 0 0 0 1.42E+08 6.53E+07 - - - 7.5569 0.9999 221125_WJC_METTL3_EV_vs_WT_F06.11690.11690.3 5.02E-05 Sep-48 K.LGHPDTLNQGEFK.E sp|P06702|S10A9_HUMAN 1 1454.7154 61.44 81276 11690 3 1454.717413 485.9124 Protein S100-A9 OS=Homo sapiens OX=9606 GN=S100A9 PE=1 SV=1 5.32 2209 - 1.64E+07 - - - 1.3886 - 2.198 0.428 - 143.1 1 2 0 0.002 13 0 0 0 1.52E+08 2.48E+06 - - - 5.4465 0.9999 221125_WJC_METTL3_EV_vs_WT_F06.11691.11691.3 0.000664 Nov-40 K.VHAYIISSLKK.E "sp|Q9NZN3|EHD3_HUMAN,sp|Q9H4M9|EHD1_HUMAN,tr|C9JC03|C9JC03_HUMAN,tr|C9J2Z4|C9J2Z4_HUMAN,tr|A0A024R571|A0A024R571_HUMAN" 5 1257.7445 1.35 81277 11691 3 1257.744643 420.2554 EH domain-containing protein 3 OS=Homo sapiens OX=9606 GN=EHD3 PE=1 SV=2 9.7 2209.1 - 1.29E+06 - - - 0.1073 - 2.124 0.394 - 195.7 1 2 0 0.0001 11 0 0 0 1.37E+07 1.01E+07 - - - 5.0727 0.9998 221125_WJC_METTL3_EV_vs_WT_F06.11693.11693.3 0.000158 Oct-40 K.VHAYIISSLK[136.11]K[136.11].E "sp|Q9NZN3|EHD3_HUMAN,sp|Q9H4M9|EHD1_HUMAN,tr|C9JC03|C9JC03_HUMAN,tr|C9J2Z4|C9J2Z4_HUMAN,tr|A0A024R571|A0A024R571_HUMAN" 5 1273.7729 1.35 81279 11693 3 1273.7735 425.5982 EH domain-containing protein 3 OS=Homo sapiens OX=9606 GN=EHD3 PE=1 SV=2 9.7 2209.2 - 1.08E+06 - - - 0.4648 - 1.714 0.397 - 147.1 1 2 0 0.0006 11 0 0 0 1.37E+07 1.01E+07 - - - 4.4967 0.9999 221125_WJC_METTL3_EV_vs_WT_F06.11694.11694.3 2.26E-07 14/60 R.NDIASHPPVEGSYAPR.R "sp|Q7KZF4|SND1_HUMAN,tr|H7C597|H7C597_HUMAN" 2 1708.8169 0.4 81280 11694 3 1708.822342 570.6129 Staphylococcal nuclease domain-containing protein 1 OS=Homo sapiens OX=9606 GN=SND1 PE=1 SV=1 5.32 2209.4 - 567396 - - - 3.1858 - 2.687 0.592 - 233.7 1 2 0 0.0054 16 0 0 0 5.51E+06 1.38E+07 - - - 7.6749 1 221125_WJC_METTL3_EV_vs_WT_F06.11695.11695.2 8.90E-09 14/24 K.VADWTGATYQDKR.Y "sp|O15371|EIF3D_HUMAN,tr|B0QYA8|B0QYA8_HUMAN,tr|B0QYA6|B0QYA6_HUMAN,tr|B0QYA5|B0QYA5_HUMAN" 4 1509.7212 1.05 81281 11695 2 1509.721565 755.8679 Eukaryotic translation initiation factor 3 subunit D OS=Homo sapiens OX=9606 GN=EIF3D PE=1 SV=1 5.93 2209.5 - 443889 - - - 0.2378 - 2.703 0.653 - 862.8 1 2 0 0.0004 13 0 0 0 1.71E+07 1.63E+07 - - - 6.416 0.9994 221125_WJC_METTL3_EV_vs_WT_F06.11700.11700.3 0.0216 Nov-52 K.ATDAEADVASLNRR.L "sp|P09493|TPM1_HUMAN,sp|P07951|TPM2_HUMAN,tr|A0A0S2Z4G6|A0A0S2Z4G6_HUMAN,tr|A7XZE4|A7XZE4_HUMAN,tr|H0YKX5|H0YKX5_HUMAN,tr|Q6ZN40|Q6ZN40_HUMAN,tr|H0YKP3|H0YKP3_HUMAN,tr|Q5TCU3|Q5TCU3_HUMAN" 8 1487.7328 2.82 81285 11700 3 1487.734693 496.9182 Tropomyosin alpha-1 chain OS=Homo sapiens OX=9606 GN=TPM1 PE=1 SV=2 4.56 2210.1 - 484039 - - - 1.2496 - 1.974 0.31 - 182.3 1 2 0 0.0019 14 0 0 0 6.67E+06 2.37E+06 - - - 3.803 1 221125_WJC_METTL3_EV_vs_WT_F06.11702.11702.2 2.27E-09 16/24 K.VADWTGATYQDK[136.11]R[166.11].Y "sp|O15371|EIF3D_HUMAN,tr|B0QYA8|B0QYA8_HUMAN,tr|B0QYA6|B0QYA6_HUMAN,tr|B0QYA5|B0QYA5_HUMAN" 4 1527.7437 1.05 81287 11702 2 1527.743782 764.8791 Eukaryotic translation initiation factor 3 subunit D OS=Homo sapiens OX=9606 GN=EIF3D PE=1 SV=1 5.93 2210.3 - 926030 - - - 0.0694 - 3.139 0.627 - 1118.1 1 2 0 0.0001 13 0 0 0 1.71E+07 1.63E+07 - - - 6.6079 1 221125_WJC_METTL3_EV_vs_WT_F06.11703.11703.2 2.59E-06 15/30 K.TIAQGNLSNTDVQAAK.N "sp|P22695|QCR2_HUMAN,tr|H3BRG4|H3BRG4_HUMAN" 2 1629.8322 1.47 81288 11703 2 1629.836791 815.9234 "Cytochrome b-c1 complex subunit 2, mitochondrial OS=Homo sapiens OX=9606 GN=UQCRC2 PE=1 SV=3" 5.5 2210.4 - 661780 - - - 2.8089 - 3.148 0.632 - 559.1 1 2 0 0.0046 16 0 0 0 1.56E+08 1.07E+08 - - - 6.5269 0.8007 221125_WJC_METTL3_EV_vs_WT_F06.11704.11704.3 1.16 Aug-52 R.FIPHENGVHTIDVK[136.11].F "sp|O75369|FLNB_HUMAN,tr|E7EN95|E7EN95_HUMAN,tr|A0A804HK76|A0A804HK76_HUMAN" 3 1612.8453 0.38 81289 11704 3 1612.847146 538.6224 Filamin-B OS=Homo sapiens OX=9606 GN=FLNB PE=1 SV=2 5.99 2210.5 - 531923 - - - 1.1501 - 1.498 0.064 - 60.5 3 2 0 0.0019 14 0 0 0 4.99E+06 1.31E+07 - - - 0.1062 0.9999 221125_WJC_METTL3_EV_vs_WT_F06.11705.11705.2 2.27E-06 22-Oct R.YQSFNNQSDLEK[136.11].E "sp|P49642|PRI1_HUMAN,tr|F8VSB2|F8VSB2_HUMAN,tr|A0A5F9ZHB6|A0A5F9ZHB6_HUMAN,tr|F8VNY2|F8VNY2_HUMAN" 4 1479.6721 0.86 81290 11705 2 1479.67021 740.8433 DNA primase small subunit OS=Homo sapiens OX=9606 GN=PRIM1 PE=1 SV=1 4.37 2210.7 - 400403 - - - -1.3023 - 2.127 0.63 - 206.7 1 2 0 -0.0019 12 0 0 0 3.43E+06 3.98E+06 - - - 5.6794 1 221125_WJC_METTL3_EV_vs_WT_F06.11710.11710.2 2.01E-08 13/30 K.TIAQGNLSNTDVQAAK[136.11].N "sp|P22695|QCR2_HUMAN,tr|H3BRG4|H3BRG4_HUMAN" 2 1637.8464 1.47 81293 11710 2 1637.847574 819.9305 "Cytochrome b-c1 complex subunit 2, mitochondrial OS=Homo sapiens OX=9606 GN=UQCRC2 PE=1 SV=3" 5.5 2211.4 - 1.59E+06 - - - 0.7089 - 2.78 0.612 - 425.5 1 2 0 0.0012 16 0 0 0 1.56E+08 1.07E+08 - - - 6.0746 0.9996 221125_WJC_METTL3_EV_vs_WT_F06.11711.11711.3 0.00157 Dec-40 R.ESVFTVEGGHR.A "sp|Q99623|PHB2_HUMAN,tr|F5H3X6|F5H3X6_HUMAN,tr|A0A7I2V5F0|A0A7I2V5F0_HUMAN,tr|F5GWA7|F5GWA7_HUMAN,tr|J3KPX7|J3KPX7_HUMAN,tr|F5GY37|F5GY37_HUMAN,tr|A0A3G2KQ93|A0A3G2KQ93_HUMAN,tr|F5H2D2|F5H2D2_HUMAN,tr|F5H0C5|F5H0C5_HUMAN" 9 1216.5837 1.04 81294 11711 3 1216.583094 406.5352 Prohibitin-2 OS=Homo sapiens OX=9606 GN=PHB2 PE=1 SV=2 5.4 2211.4 - 1.34E+06 - - - -0.457 - 1.786 0.338 - 129.7 1 2 0 -0.0006 11 0 0 0 4.28E+07 4.11E+07 - - - 3.9558 0.9991 221125_WJC_METTL3_EV_vs_WT_F06.11714.11714.2 0.0146 24-Nov K.LGHPDTLNQGEFK.E sp|P06702|S10A9_HUMAN 1 1454.7154 103.87 81297 11714 2 1454.717696 728.365 Protein S100-A9 OS=Homo sapiens OX=9606 GN=S100A9 PE=1 SV=1 5.32 2211.6 - 1.78E+06 - - - 1.5831 - 1.912 0.319 - 238.4 1 2 0 0.0023 13 0 0 0 1.50E+07 1.44E+05 - - - 3.0599 0.9995 221125_WJC_METTL3_EV_vs_WT_F06.11715.11715.3 0.0205 14/40 R.ESVFTVEGGHR[166.11].A "sp|Q99623|PHB2_HUMAN,tr|F5H3X6|F5H3X6_HUMAN,tr|A0A7I2V5F0|A0A7I2V5F0_HUMAN,tr|F5GWA7|F5GWA7_HUMAN,tr|J3KPX7|J3KPX7_HUMAN,tr|F5GY37|F5GY37_HUMAN,tr|A0A3G2KQ93|A0A3G2KQ93_HUMAN,tr|F5H2D2|F5H2D2_HUMAN,tr|F5H0C5|F5H0C5_HUMAN" 9 1226.5919 1.04 81298 11715 3 1226.591294 409.8712 Prohibitin-2 OS=Homo sapiens OX=9606 GN=PHB2 PE=1 SV=2 5.4 2211.7 - 1.20E+06 - - - -0.5104 - 1.886 0.315 - 195.7 1 2 0 -0.0006 11 0 0 0 4.27E+07 4.10E+07 - - - 3.8542 0.9998 221125_WJC_METTL3_EV_vs_WT_F06.11716.11716.3 2.82E-05 13/60 R.ESLAEEHEGLVGEGQR[166.11].S sp|Q10570|CPSF1_HUMAN 1 1748.8205 0.72 81299 11716 3 1748.815896 583.9474 Cleavage and polyadenylation specificity factor subunit 1 OS=Homo sapiens OX=9606 GN=CPSF1 PE=1 SV=2 4.32 2211.9 - 901249 - - - -2.6189 - 2.513 0.402 - 193.8 1 2 0 -0.0046 16 0 0 0 1.26E+07 1.76E+07 - - - 5.385 0.9969 221125_WJC_METTL3_EV_vs_WT_F06.11718.11718.3 0.00156 Sep-48 R.GKEGSDANPFLSK.R "sp|Q8TEK3|DOT1L_HUMAN,tr|H7C2S2|H7C2S2_HUMAN" 2 1348.6623 0.31 81301 11718 3 1348.664385 450.5614 "Histone-lysine N-methyltransferase, H3 lysine-79 specific OS=Homo sapiens OX=9606 GN=DOT1L PE=1 SV=3" 6.07 2212 - 509704 - - - 1.5504 - 1.641 0.359 - 74.2 1 2 1 0.0021 13 0 0 0 5.76E+06 1.83E+07 - - - 3.8848 0.9955 221125_WJC_METTL3_EV_vs_WT_F06.11727.11727.3 0.0169 Sep-44 K.ESELK[136.11]PLVGESR[166.11].S "sp|Q709C8|VP13C_HUMAN,tr|A0A3B3IT88|A0A3B3IT88_HUMAN" 2 1360.7317 0.64 81308 11727 3 1360.733511 454.5845 Vacuolar protein sorting-associated protein 13C OS=Homo sapiens OX=9606 GN=VPS13C PE=1 SV=1 4.79 2213 - 714437 - - - 1.3199 - 1.637 0.23 - 108.1 1 2 0 0.0018 12 0 0 0 6.22E+06 9.73E+06 - - - 2.4699 1 221125_WJC_METTL3_EV_vs_WT_F06.11728.11728.3 0.00028 16/44 R.TVEGVLIVHEHR.L "sp|O43809|CPSF5_HUMAN,tr|H3BV41|H3BV41_HUMAN,tr|H3BND3|H3BND3_HUMAN" 3 1387.7572 1.35 81309 11728 3 1387.755684 463.593 Cleavage and polyadenylation specificity factor subunit 5 OS=Homo sapiens OX=9606 GN=NUDT21 PE=1 SV=1 5.94 2213.1 - 606425 - - - -1.091 - 3.062 0.496 - 340.7 1 2 0 -0.0015 12 0 0 0 1.04E+07 7.72E+06 - - - 7.1714 0.9999 221125_WJC_METTL3_EV_vs_WT_F06.11730.11730.2 6.95E-06 20-Nov R.ESVFTVEGGHR[166.11].A "sp|Q99623|PHB2_HUMAN,tr|F5H3X6|F5H3X6_HUMAN,tr|A0A7I2V5F0|A0A7I2V5F0_HUMAN,tr|F5GWA7|F5GWA7_HUMAN,tr|J3KPX7|J3KPX7_HUMAN,tr|F5GY37|F5GY37_HUMAN,tr|A0A3G2KQ93|A0A3G2KQ93_HUMAN,tr|F5H2D2|F5H2D2_HUMAN,tr|F5H0C5|F5H0C5_HUMAN" 9 1226.5919 1.05 81311 11730 2 1226.592294 614.3032 Prohibitin-2 OS=Homo sapiens OX=9606 GN=PHB2 PE=1 SV=2 5.4 2213.3 - 379263 - - - 0.3049 - 2.23 0.535 - 512.9 1 2 0 0.0004 11 0 0 0 7.62E+06 7.23E+06 - - - 5.162 0.988 221125_WJC_METTL3_EV_vs_WT_F06.11731.11731.2 9.37E-08 22-Nov V.ADWTGATYQDKR.Y "sp|O15371|EIF3D_HUMAN,tr|B0QYA8|B0QYA8_HUMAN,tr|B0QYA6|B0QYA6_HUMAN,tr|B0QYA5|B0QYA5_HUMAN" 4 1410.6528 0.48 81312 11731 2 1410.649964 706.3337 Eukaryotic translation initiation factor 3 subunit D OS=Homo sapiens OX=9606 GN=EIF3D PE=1 SV=1 6 2213.4 - 299477 - - - -2.0047 - 2.134 0.589 - 364.5 1 1 0 -0.0028 12 0 0 0 2.61E+06 5.50E+06 - - - 5.3849 1 221125_WJC_METTL3_EV_vs_WT_F06.11732.11732.2 1.00E-09 28-Dec K.TYTSTSNNSISGSLK.R "sp|P55197|AF10_HUMAN,tr|Q5JT35|Q5JT35_HUMAN" 2 1558.7475 3.4 81313 11732 2 1558.751073 780.381 Protein AF-10 OS=Homo sapiens OX=9606 GN=MLLT10 PE=1 SV=2 8.26 2213.6 - 294721 - - - 2.3044 - 2.503 0.68 - 289.9 1 2 0 0.0036 15 0 0 0 5.62E+06 1.65E+06 - - - 6.318 1 221125_WJC_METTL3_EV_vs_WT_F06.11733.11733.2 5.65E-06 30-Nov R.AAAYSAQVQPVDGATR[166.11].K "sp|Q9H7E9|CH033_HUMAN,tr|A0A3B3IRR6|A0A3B3IRR6_HUMAN,tr|A0A3B3ITA3|A0A3B3ITA3_HUMAN,tr|A0A3B3IT54|A0A3B3IT54_HUMAN" 4 1613.8037 1.25 81314 11733 2 1613.808246 807.9091 UPF0488 protein C8orf33 OS=Homo sapiens OX=9606 GN=C8orf33 PE=1 SV=1 5.88 2213.7 - 150802 - - - 2.8145 - 2.821 0.634 - 261.3 1 2 0 0.0045 16 0 0 0 1.53E+07 1.22E+07 - - - 6.272 1 221125_WJC_METTL3_EV_vs_WT_F06.11737.11737.3 1.10E-08 15/60 R.ESLAEEHEGLVGEGQR.S sp|Q10570|CPSF1_HUMAN 1 1738.8122 0.72 81316 11737 3 1738.813472 580.6113 Cleavage and polyadenylation specificity factor subunit 1 OS=Homo sapiens OX=9606 GN=CPSF1 PE=1 SV=2 4.32 2214.2 - 932653 - - - 0.7281 - 2.737 0.606 - 264.8 1 2 0 0.0013 16 0 0 0 1.26E+07 1.76E+07 - - - 7.8794 0.9996 221125_WJC_METTL3_EV_vs_WT_F06.11739.11739.3 4.44E-05 Nov-48 K.VVDR[166.11]DSEEAEIIR[166.11].K "sp|P09874|PARP1_HUMAN,tr|A0A7I2V3E1|A0A7I2V3E1_HUMAN" 2 1549.7851 0.56 81318 11739 3 1549.788187 517.6023 Poly [ADP-ribose] polymerase 1 OS=Homo sapiens OX=9606 GN=PARP1 PE=1 SV=4 4.18 2214.4 - 974808 - - - 1.9983 - 2.445 0.455 - 177.6 1 2 1 0.0031 13 0 0 0 7.57E+06 1.35E+07 - - - 6.036 0.9988 221125_WJC_METTL3_EV_vs_WT_F06.11745.11745.3 0.0061 Dec-44 K.TK[136.11]VEAFQTTISK[136.11].Y "sp|Q9UL46|PSME2_HUMAN,tr|A0A087X1Z3|A0A087X1Z3_HUMAN,tr|H0YM70|H0YM70_HUMAN" 3 1367.7631 0.74 81322 11745 3 1367.763369 456.9283 Proteasome activator complex subunit 2 OS=Homo sapiens OX=9606 GN=PSME2 PE=1 SV=4 8.26 2215 - 853580 - - - 0.174 - 2.135 0.333 - 150.8 1 2 1 0.0002 12 0 0 0 6.39E+06 8.63E+06 - - - 4.3549 0.9912 221125_WJC_METTL3_EV_vs_WT_F06.11748.11748.2 1.02E-05 20-Sep R.ESVFTVEGGHR.A "sp|Q99623|PHB2_HUMAN,tr|F5H3X6|F5H3X6_HUMAN,tr|A0A7I2V5F0|A0A7I2V5F0_HUMAN,tr|F5GWA7|F5GWA7_HUMAN,tr|J3KPX7|J3KPX7_HUMAN,tr|F5GY37|F5GY37_HUMAN,tr|A0A3G2KQ93|A0A3G2KQ93_HUMAN,tr|F5H2D2|F5H2D2_HUMAN,tr|F5H0C5|F5H0C5_HUMAN" 9 1216.5837 1.05 81325 11748 2 1216.591295 609.2991 Prohibitin-2 OS=Homo sapiens OX=9606 GN=PHB2 PE=1 SV=2 5.4 2215.4 - 478234 - - - 6.284 - 1.874 0.461 - 394.8 1 2 0 0.0076 11 0 0 0 7.62E+06 7.23E+06 - - - 4.1426 0.8634 221125_WJC_METTL3_EV_vs_WT_F06.11754.11754.2 5.34 20-Apr K.EFAEYVTNHYR.M "sp|Q96PV0|SYGP1_HUMAN,tr|B7ZCA0|B7ZCA0_HUMAN,tr|A0A1B0GW70|A0A1B0GW70_HUMAN,tr|A0A804HJ92|A0A804HJ92_HUMAN,tr|A0A2R8YDS2|A0A2R8YDS2_HUMAN,tr|A0A0A0MQZ2|A0A0A0MQZ2_HUMAN,tr|A0A2R8Y6T2|A0A2R8Y6T2_HUMAN" 7 1427.647 129.23 81329 11754 2 1427.642449 714.8308 Ras\Rap GTPase-activating protein SynGAP OS=Homo sapiens OX=9606 GN=SYNGAP1 PE=1 SV=4 5.4 2216.1 - 2.78E+06 - - - -3.1731 - 1.004 0.132 - 38.8 2 2 0 -0.0045 11 0 0 0 3.58E+07 2.77E+05 - - - -0.1091 0.9303 221125_WJC_METTL3_EV_vs_WT_F06.11757.11757.4 0.233 Dec-72 K.IITIEETHEELKK.Q "sp|Q92547|TOPB1_HUMAN,tr|A0A2R8YD63|A0A2R8YD63_HUMAN" 2 1581.8614 0.93 81332 11757 4 1581.86417 396.4726 DNA topoisomerase 2-binding protein 1 OS=Homo sapiens OX=9606 GN=TOPBP1 PE=1 SV=3 4.91 2216.5 - 577701 - - - 1.7587 - 1.817 0.133 - 91.7 1 2 0 0.0028 13 0 0 0 5.32E+06 5.74E+06 - - - 0.6043 0.8752 221125_WJC_METTL3_EV_vs_WT_F06.11759.11759.3 0.34 Sep-40 K.MYDLQYQGGHK.E sp|O00257|CBX4_HUMAN 1 1338.6027 1.23 81334 11759 3 1338.604278 447.2082 E3 SUMO-protein ligase CBX4 OS=Homo sapiens OX=9606 GN=CBX4 PE=1 SV=3 6.49 2216.8 - 549287 - - - 1.2005 - 1.173 0.128 - 68.2 1 2 0 0.0016 11 0 0 0 5.75E+06 4.69E+06 - - - 0.4199 0.9846 221125_WJC_METTL3_EV_vs_WT_F06.11763.11763.2 0.000375 18-Aug H.SSEC[160.03]WNVGSR.W sp|Q7LGA3|HS2ST_HUMAN 1 1180.4931 1.1 81338 11763 2 1180.493528 591.2538 Heparan sulfate 2-O-sulfotransferase 1 OS=Homo sapiens OX=9606 GN=HS2ST1 PE=1 SV=1 5.72 2217.3 - 408783 - - - 0.3448 - 1.848 0.412 - 259.7 1 1 0 0.0004 10 0 0 0 6.40E+06 5.80E+06 - - - 3.7981 0.9639 221125_WJC_METTL3_EV_vs_WT_F06.11768.11768.3 0.947 Oct-44 R.KLNTETFGVSGR.F sp|Q9BX40|LS14B_HUMAN 1 1307.6834 0.76 81342 11768 3 1307.683703 436.9017 Protein LSM14 homolog B OS=Homo sapiens OX=9606 GN=LSM14B PE=1 SV=1 8.75 2217.9 - 4.50E+06 - - - 0.2592 - 1.482 0.127 - 51.8 1 2 0 0.0003 12 0 0 0 1.63E+08 2.15E+08 - - - 1.0463 0.9991 221125_WJC_METTL3_EV_vs_WT_F06.11771.11771.3 0.00149 13/32 R.EHLLDQLKR.K "sp|P52732|KIF11_HUMAN,tr|A0A7I2V3A9|A0A7I2V3A9_HUMAN" 2 1150.6459 3.73 81344 11771 3 1150.645579 384.5559 Kinesin-like protein KIF11 OS=Homo sapiens OX=9606 GN=KIF11 PE=1 SV=2 6.85 2218.2 - 1.30E+06 - - - -0.2407 - 2.363 0.201 - 285.2 1 2 0 -0.0003 9 0 0 0 2.04E+07 5.47E+06 - - - 3.3725 1 221125_WJC_METTL3_EV_vs_WT_F06.11772.11772.3 4.07E-05 14/48 K.VADWTGATYQDK[136.11]R[166.11].Y "sp|O15371|EIF3D_HUMAN,tr|B0QYA8|B0QYA8_HUMAN,tr|B0QYA6|B0QYA6_HUMAN,tr|B0QYA5|B0QYA5_HUMAN" 4 1527.7437 1.01 81345 11772 3 1527.745772 510.2552 Eukaryotic translation initiation factor 3 subunit D OS=Homo sapiens OX=9606 GN=EIF3D PE=1 SV=1 5.93 2218.2 - 3.08E+06 - - - 1.372 - 2.753 0.465 - 375.2 1 2 0 0.0021 13 0 0 0 2.41E+08 2.38E+08 - - - 6.4694 0.9999 221125_WJC_METTL3_EV_vs_WT_F06.11773.11773.3 4.72E-05 Nov-36 K.SLGHFENLQK.Y "sp|Q9ULV3|CIZ1_HUMAN,tr|Q5SYW2|Q5SYW2_HUMAN,tr|F5H2X7|F5H2X7_HUMAN,tr|H0Y5D5|H0Y5D5_HUMAN,tr|A0A0U1RQR2|A0A0U1RQR2_HUMAN,tr|A0A494C0L7|A0A494C0L7_HUMAN,tr|Q9BTG3|Q9BTG3_HUMAN" 7 1171.5986 1.53 81346 11773 3 1171.599206 391.5401 Cip1-interacting zinc finger protein OS=Homo sapiens OX=9606 GN=CIZ1 PE=1 SV=2 6.47 2218.3 - 2.18E+06 - - - 0.5411 - 1.943 0.391 - 139.2 1 2 0 0.0006 10 0 0 0 2.24E+07 1.46E+07 - - - 4.8389 1 221125_WJC_METTL3_EV_vs_WT_F06.11774.11774.3 2.39E-05 Nov-48 K.EVNEQTHFASMPR.D sp|O15226|NKRF_HUMAN 1 1544.7042 5.09 81347 11774 3 1544.703031 515.9087 NF-kappa-B-repressing factor OS=Homo sapiens OX=9606 GN=NKRF PE=1 SV=2 5.4 2218.3 - 1.15E+06 - - - -0.7412 - 2.179 0.521 - 195.5 1 2 0 -0.0011 13 0 0 0 1.74E+08 3.41E+07 - - - 6.46 0.9904 221125_WJC_METTL3_EV_vs_WT_F06.11776.11776.3 7.70E-06 16/36 K.LK[136.11]HILILQNK[136.11].L "sp|Q2VIR3|IF2GL_HUMAN,sp|P41091|IF2G_HUMAN" 2 1234.8096 1.03 81349 11776 3 1234.810806 412.6105 Eukaryotic translation initiation factor 2 subunit 3B OS=Homo sapiens OX=9606 GN=EIF2S3B PE=2 SV=2 10 2218.6 - 691094 - - - 0.954 - 2.095 0.193 - 225.5 1 2 1 0.0012 10 0 0 0 6.16E+06 5.99E+06 - - - 2.8513 0.8923 221125_WJC_METTL3_EV_vs_WT_F06.11778.11778.3 0.039 Sep-48 K.LIQDQQEQIQHLK.S "sp|Q92878|RAD50_HUMAN,tr|A0A494C1B7|A0A494C1B7_HUMAN,tr|A0A1W2PQ90|A0A1W2PQ90_HUMAN" 3 1619.8631 1.02 81351 11778 3 1619.875392 540.9616 DNA repair protein RAD50 OS=Homo sapiens OX=9606 GN=RAD50 PE=1 SV=1 5.32 2218.8 - 569852 - - - 7.5759 - 2.049 0.245 - 78.8 3 2 0 0.0123 13 0 0 0 7.84E+06 7.72E+06 - - - 2.9922 0.9999 221125_WJC_METTL3_EV_vs_WT_F06.11780.11780.2 0.000387 13/26 K.IANVVINQSANDSK[136.11].V "sp|O14981|BTAF1_HUMAN,tr|A0A0A0MTH9|A0A0A0MTH9_HUMAN" 2 1479.7773 0.33 81353 11780 2 1479.775971 740.8959 TATA-binding protein-associated factor 172 OS=Homo sapiens OX=9606 GN=BTAF1 PE=1 SV=2 5.84 2219.1 - 284678 - - - -0.8785 - 2.707 0.443 - 628 1 2 0 -0.0013 14 0 0 0 8.90E+05 2.66E+06 - - - 4.8116 0.9999 221125_WJC_METTL3_EV_vs_WT_F06.11787.11787.3 0.0626 16/36 R.KGFPHVIYAR.L "sp|Q13485|SMAD4_HUMAN,tr|K7EIU8|K7EIU8_HUMAN,tr|K7EL18|K7EL18_HUMAN,tr|K7EL15|K7EL15_HUMAN,tr|K7EIJ2|K7EIJ2_HUMAN,tr|K7ES96|K7ES96_HUMAN" 6 1186.6611 1.11 81358 11787 3 1186.662458 396.561 Mothers against decapentaplegic homolog 4 OS=Homo sapiens OX=9606 GN=SMAD4 PE=1 SV=1 9.99 2219.9 - 1.25E+06 - - - 1.1334 - 2.962 0.37 - 447.9 1 2 0 0.0013 10 0 0 0 1.33E+07 1.19E+07 - - - 5.836 0.9993 221125_WJC_METTL3_EV_vs_WT_F06.11789.11789.3 0.00673 Dec-36 R.K[136.11]GFPHVIYAR[166.11].L "sp|Q13485|SMAD4_HUMAN,tr|K7EIU8|K7EIU8_HUMAN,tr|K7EL18|K7EL18_HUMAN,tr|K7EL15|K7EL15_HUMAN,tr|K7EIJ2|K7EIJ2_HUMAN,tr|K7ES96|K7ES96_HUMAN" 6 1204.6836 1.11 81360 11789 3 1204.686342 402.5685 Mothers against decapentaplegic homolog 4 OS=Homo sapiens OX=9606 GN=SMAD4 PE=1 SV=1 9.99 2220.1 - 1.03E+06 - - - 2.2902 - 2.4 0.279 - 194.3 1 2 0 0.0028 10 0 0 0 1.33E+07 1.19E+07 - - - 4.2066 0.9998 221125_WJC_METTL3_EV_vs_WT_F06.11792.11792.2 2.16E-06 18-Oct K.SLGHFENLQK.Y "sp|Q9ULV3|CIZ1_HUMAN,tr|Q5SYW2|Q5SYW2_HUMAN,tr|F5H2X7|F5H2X7_HUMAN,tr|H0Y5D5|H0Y5D5_HUMAN,tr|A0A0U1RQR2|A0A0U1RQR2_HUMAN,tr|A0A494C0L7|A0A494C0L7_HUMAN,tr|Q9BTG3|Q9BTG3_HUMAN" 7 1171.5986 1.84 81363 11792 2 1171.600174 586.8066 Cip1-interacting zinc finger protein OS=Homo sapiens OX=9606 GN=CIZ1 PE=1 SV=2 6.47 2220.4 - 381759 - - - 1.3674 - 2.156 0.508 - 216.8 1 2 0 0.0016 10 0 0 0 3.91E+06 2.12E+06 - - - 4.937 0.9801 221125_WJC_METTL3_EV_vs_WT_F06.11793.11793.3 0.299 Aug-44 K.VFEHDSVELNC[160.03]K[136.11].M "sp|P10768|ESTD_HUMAN,tr|U3KQT1|U3KQT1_HUMAN" 2 1483.6857 2.94 81364 11793 3 1483.687923 495.5692 S-formylglutathione hydrolase OS=Homo sapiens OX=9606 GN=ESD PE=1 SV=2 4.65 2220.5 - 751297 - - - 1.5124 - 1.302 0.21 - 40.6 1 2 0 0.0022 12 0 0 0 1.82E+07 6.18E+06 - - - 1.6122 1 221125_WJC_METTL3_EV_vs_WT_F06.11795.11795.3 4.26E-05 14/44 K.ISPFEHQTYC[160.03]QR[166.11].T "sp|P27361|MK03_HUMAN,sp|P28482|MK01_HUMAN,tr|E9PQW4|E9PQW4_HUMAN,tr|E9PJF0|E9PJF0_HUMAN,tr|E9PBK7|E9PBK7_HUMAN" 5 1574.7175 0.23 81366 11795 3 1574.720844 525.9131 Mitogen-activated protein kinase 3 OS=Homo sapiens OX=9606 GN=MAPK3 PE=1 SV=4 6.74 2220.8 - 317071 - - - 2.1032 - 2.408 0.526 - 341.4 1 2 0 0.0033 12 0 0 0 2.58E+06 1.12E+07 - - - 6.8394 0.9998 221125_WJC_METTL3_EV_vs_WT_F06.11797.11797.2 0.231 13/26 K.NGQVIGIGAGQQSR[166.11].L "sp|P31939|PUR9_HUMAN,tr|H7C1S2|H7C1S2_HUMAN" 2 1393.7301 1.1 81368 11797 2 1393.731857 697.8723 Bifunctional purine biosynthesis protein ATIC OS=Homo sapiens OX=9606 GN=ATIC PE=1 SV=3 9.75 2221 - 275832 - - - 1.2284 - 2.499 0.473 - 559.5 1 2 0 0.0017 14 0 0 0 5.02E+06 4.57E+06 - - - 4.8324 1 221125_WJC_METTL3_EV_vs_WT_F06.11798.11798.2 1.93E-08 26-Dec R.STVVDNDADFQGTK[136.11].R sp|Q8IYH5|ZZZ3_HUMAN 1 1503.6933 2.14 81369 11798 2 1503.695723 752.8539 ZZ-type zinc finger-containing protein 3 OS=Homo sapiens OX=9606 GN=ZZZ3 PE=1 SV=1 3.93 2221.1 - 242726 - - - 1.6333 - 2.528 0.694 - 438.3 1 2 0 0.0025 14 0 0 0 5.07E+06 2.37E+06 - - - 6.4934 0.9998 221125_WJC_METTL3_EV_vs_WT_F06.11805.11805.3 0.000987 Nov-40 K.QDLPPLDEK[136.11]PR[166.11].N "sp|O95757|HS74L_HUMAN,tr|D6RJ96|D6RJ96_HUMAN,tr|E9PDE8|E9PDE8_HUMAN" 3 1324.7106 0.21 81374 11805 3 1324.711734 442.5775 Heat shock 70 kDa protein 4L OS=Homo sapiens OX=9606 GN=HSPA4L PE=1 SV=3 4.56 2221.9 - 979763 - - - 0.8674 - 2.123 0.359 - 202 1 2 0 0.0011 11 0 0 0 1.49E+06 7.14E+06 - - - 4.6808 0.9785 221125_WJC_METTL3_EV_vs_WT_F06.11806.11806.3 0.00205 13/40 R.SLHDALC[160.03]VVK[136.11]R[166.11].V "sp|P17987|TCPA_HUMAN,tr|F5GZ03|F5GZ03_HUMAN,tr|F5H282|F5H282_HUMAN,tr|E7EQR6|E7EQR6_HUMAN,tr|E7ERF2|E7ERF2_HUMAN" 5 1314.7197 0.22 81375 11806 3 1315.718917 439.2472 T-complex protein 1 subunit alpha OS=Homo sapiens OX=9606 GN=TCP1 PE=1 SV=1 7.97 2222 - 873872 - - - 760.0152 - 2.124 0.381 - 216.3 1 2 0 0.9992 11 0 0 0 2.36E+06 1.09E+07 - - - 4.651 0.9993 221125_WJC_METTL3_EV_vs_WT_F06.11807.11807.2 5.56E-05 22-Dec K.SGPSVPVSVQTK[136.11].D sp|Q9Y2W2|WBP11_HUMAN 1 1192.6543 0.32 81376 11807 2 1192.657032 597.3344 WW domain-binding protein 11 OS=Homo sapiens OX=9606 GN=WBP11 PE=1 SV=1 8.47 2222.1 - 788174 - - - 2.289 - 2.104 0.379 - 364.3 1 2 0 0.0027 12 0 0 0 2.35E+06 7.41E+06 - - - 3.7966 1 221125_WJC_METTL3_EV_vs_WT_F06.11808.11808.2 0.00101 14/30 R.AAAYSAQVQPVDGATR.K "sp|Q9H7E9|CH033_HUMAN,tr|A0A3B3IRR6|A0A3B3IRR6_HUMAN,tr|A0A3B3ITA3|A0A3B3ITA3_HUMAN,tr|A0A3B3IT54|A0A3B3IT54_HUMAN" 4 1603.7954 1.29 81377 11808 2 1603.795908 802.905 UPF0488 protein C8orf33 OS=Homo sapiens OX=9606 GN=C8orf33 PE=1 SV=1 5.88 2222.3 - 540533 - - - 0.2955 - 2.909 0.56 - 497.9 1 2 0 0.0005 16 0 0 0 1.58E+07 1.22E+07 - - - 5.8023 0.9999 221125_WJC_METTL3_EV_vs_WT_F06.11809.11809.2 2.45E-06 26-Sep R.STVVDNDADFQGTK.R sp|Q8IYH5|ZZZ3_HUMAN 1 1495.6791 2.18 81378 11809 2 1495.679573 748.8468 ZZ-type zinc finger-containing protein 3 OS=Homo sapiens OX=9606 GN=ZZZ3 PE=1 SV=1 3.93 2222.4 - 503892 - - - 0.3383 - 2.059 0.634 - 203.1 1 2 0 0.0005 14 0 0 0 5.18E+06 2.37E+06 - - - 5.5359 0.9999 221125_WJC_METTL3_EV_vs_WT_F06.11814.11814.3 0.000225 17/60 R.RIPPPGSQPPVLNTSR.E "sp|Q5JSZ5|PRC2B_HUMAN,tr|A0A804HKU3|A0A804HKU3_HUMAN,tr|A0A804HJR4|A0A804HJR4_HUMAN" 3 1714.9479 2.73 81383 11814 3 1714.952459 572.6566 Protein PRRC2B OS=Homo sapiens OX=9606 GN=PRRC2B PE=1 SV=2 12 2223.1 - 316887 - - - 2.6864 - 3.059 0.449 - 412.3 1 2 0 0.0046 16 0 0 0 3.20E+06 1.17E+06 - - - 6.4135 1 221125_WJC_METTL3_EV_vs_WT_F06.11820.11820.3 1.79E-06 15/44 K.TVFAEHISDEC[160.03]K.R "sp|P39023|RL3_HUMAN,tr|G5E9G0|G5E9G0_HUMAN,tr|H7C3M2|H7C3M2_HUMAN,tr|F8WCR1|F8WCR1_HUMAN,tr|B5MCW2|B5MCW2_HUMAN,tr|H7C422|H7C422_HUMAN" 6 1434.6449 0.95 81387 11820 3 1434.647042 479.2223 60S ribosomal protein L3 OS=Homo sapiens OX=9606 GN=RPL3 PE=1 SV=2 4.65 2223.7 - 3.27E+06 - - - 1.4721 - 2.761 0.544 - 247.4 1 2 0 0.0021 12 0 0 0 4.34E+07 4.56E+07 - - - 7.4195 1 221125_WJC_METTL3_EV_vs_WT_F06.11821.11821.3 2.37E-06 14/44 K.TVFAEHISDEC[160.03]K[136.11].R "sp|P39023|RL3_HUMAN,tr|G5E9G0|G5E9G0_HUMAN,tr|H7C3M2|H7C3M2_HUMAN,tr|F8WCR1|F8WCR1_HUMAN,tr|B5MCW2|B5MCW2_HUMAN,tr|H7C422|H7C422_HUMAN" 6 1442.6591 0.95 81388 11821 3 1442.661744 481.8937 60S ribosomal protein L3 OS=Homo sapiens OX=9606 GN=RPL3 PE=1 SV=2 4.65 2223.7 - 3.28E+06 - - - 1.8119 - 2.501 0.543 - 163.3 1 2 0 0.0026 12 0 0 0 4.34E+07 4.56E+07 - - - 7.1341 0.9999 221125_WJC_METTL3_EV_vs_WT_F06.11822.11822.3 0.000362 Oct-44 K.EYSGFAGVSR[166.11]PR[166.11].G "sp|Q9NYF8|BCLF1_HUMAN,tr|H0YF63|H0YF63_HUMAN,tr|E9PK91|E9PK91_HUMAN,tr|H0YF14|H0YF14_HUMAN" 4 1344.6689 1.89 81389 11822 3 1344.671568 449.2303 Bcl-2-associated transcription factor 1 OS=Homo sapiens OX=9606 GN=BCLAF1 PE=1 SV=2 8.85 2223.8 - 3.14E+06 - - - 1.9559 - 2.043 0.453 - 175.2 1 2 0 0.0026 12 0 0 0 7.34E+08 3.88E+08 - - - 5.57 0.9999 221125_WJC_METTL3_EV_vs_WT_F06.11823.11823.3 3.95E-05 Dec-44 K.EYSGFAGVSRPR.G "sp|Q9NYF8|BCLF1_HUMAN,tr|H0YF63|H0YF63_HUMAN,tr|E9PK91|E9PK91_HUMAN,tr|H0YF14|H0YF14_HUMAN" 4 1324.6524 1.89 81390 11823 3 1324.654566 442.5581 Bcl-2-associated transcription factor 1 OS=Homo sapiens OX=9606 GN=BCLAF1 PE=1 SV=2 8.85 2223.8 - 3.12E+06 - - - 1.6367 - 1.912 0.459 - 189.3 1 2 0 0.0022 12 0 0 0 7.33E+08 3.87E+08 - - - 5.4534 1 221125_WJC_METTL3_EV_vs_WT_F06.11824.11824.3 1.16E-05 Sep-52 R.ARPATDSFDDYPPR.R "sp|P23588|IF4B_HUMAN,tr|E7EX17|E7EX17_HUMAN,tr|F8VSC7|F8VSC7_HUMAN,tr|F8W0K0|F8W0K0_HUMAN,tr|F8VP89|F8VP89_HUMAN" 5 1606.7376 2.03 81391 11824 3 1606.737805 536.5865 Eukaryotic translation initiation factor 4B OS=Homo sapiens OX=9606 GN=EIF4B PE=1 SV=2 4.43 2223.9 - 820332 - - - 0.1369 - 2.02 0.512 - 113.6 1 2 0 0.0002 14 0 0 0 1.18E+07 5.84E+06 - - - 6.1167 0.9993 221125_WJC_METTL3_EV_vs_WT_F06.11825.11825.2 0.00183 24-Sep R.APEPTPQQVAQQQ.- "sp|Q14839|CHD4_HUMAN,tr|A0A2R8Y4X2|A0A2R8Y4X2_HUMAN,tr|A0A2U3TZM0|A0A2U3TZM0_HUMAN,tr|A0A2R8YD40|A0A2R8YD40_HUMAN,tr|A0A2R8Y5J0|A0A2R8Y5J0_HUMAN,tr|A0A2R8Y425|A0A2R8Y425_HUMAN,tr|A0A2R8YFK9|A0A2R8YFK9_HUMAN,tr|A0A0C4DGG9|A0A0C4DGG9_HUMAN,tr|A0A2R8YFD8|A0A2R8YFD8_HUMAN,tr|A0A2R8YDW2|A0A2R8YDW2_HUMAN,tr|A0A2R8Y7I0|A0A2R8Y7I0_HUMAN,tr|F5GWX5|F5GWX5_HUMAN,tr|A0A2R8Y521|A0A2R8Y521_HUMAN,tr|A0A2R8YDJ9|A0A2R8YDJ9_HUMAN,tr|A0A2R8Y212|A0A2R8Y212_HUMAN" 15 1420.6947 - 81392 11825 2 1420.697948 711.3546 Chromodomain-helicase-DNA-binding protein 4 OS=Homo sapiens OX=9606 GN=CHD4 PE=1 SV=2 4 2224 - 602719 - - - 2.3165 - 1.837 0.445 - 205.4 1 2 0 0.0033 13 0 0 0 - - - - - 3.8875 0.9991 221125_WJC_METTL3_EV_vs_WT_F06.11827.11827.3 0.00176 Dec-32 R.TR[166.11]WDSELQR[166.11].E "sp|Q969N2|PIGT_HUMAN,tr|A0A1W2PRB4|A0A1W2PRB4_HUMAN,tr|A0A1W2PRZ8|A0A1W2PRZ8_HUMAN,tr|A0A1W2PP53|A0A1W2PP53_HUMAN,tr|H7C2Y2|H7C2Y2_HUMAN,tr|A0A1W2PPS0|A0A1W2PPS0_HUMAN,tr|A0A1W2PP98|A0A1W2PP98_HUMAN,tr|A0A1W2PRL6|A0A1W2PRL6_HUMAN,tr|A0A1W2PR92|A0A1W2PR92_HUMAN,tr|A0A1W2PR22|A0A1W2PR22_HUMAN,tr|A0A1W2PPI8|A0A1W2PPI8_HUMAN,tr|A0A1W2PPU8|A0A1W2PPU8_HUMAN,tr|A0A1W2PRG1|A0A1W2PRG1_HUMAN,tr|A0A1W2PRV7|A0A1W2PRV7_HUMAN,tr|A0A1W2PQ52|A0A1W2PQ52_HUMAN,tr|A0A1W2PRH2|A0A1W2PRH2_HUMAN,tr|A0A1W2PNP0|A0A1W2PNP0_HUMAN,tr|A0A1W2PQL3|A0A1W2PQL3_HUMAN,tr|A0A1W2PQI9|A0A1W2PQI9_HUMAN,tr|A0A1W2PNW9|A0A1W2PNW9_HUMAN,tr|B7Z7C5|B7Z7C5_HUMAN,tr|A0A1W2PRH8|A0A1W2PRH8_HUMAN,tr|A0A1W2PR70|A0A1W2PR70_HUMAN,tr|A0A1W2PP57|A0A1W2PP57_HUMAN,tr|A0A1W2PPQ7|A0A1W2PPQ7_HUMAN,tr|A0A1W2PP03|A0A1W2PP03_HUMAN,tr|A0A1W2PP13|A0A1W2PP13_HUMAN,tr|A0A1W2PQ29|A0A1W2PQ29_HUMAN,tr|A0A1W2PPC3|A0A1W2PPC3_HUMAN,tr|A0A1W2PNS2|A0A1W2PNS2_HUMAN,tr|A0A1W2PNZ5|A0A1W2PNZ5_HUMAN" 31 1209.6005 1.41 81394 11827 3 1209.60276 404.2075 GPI transamidase component PIG-T OS=Homo sapiens OX=9606 GN=PIGT PE=1 SV=1 5.74 2224.2 - 480462 - - - 1.8485 - 2.21 0.372 - 224.6 1 2 1 0.0022 9 0 0 0 3.81E+06 2.70E+06 - - - 5.0767 0.9624 221125_WJC_METTL3_EV_vs_WT_F06.11828.11828.3 8.14E-05 Oct-64 L.LQDDAHPTLVTYADHSK[136.11].L "sp|Q86U44|MTA70_HUMAN,tr|F5H6D8|F5H6D8_HUMAN,tr|H0YFV6|H0YFV6_HUMAN,tr|B4DTN4|B4DTN4_HUMAN" 4 1917.9312 0.16 81395 11828 3 1917.93534 640.3177 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 5.13 2224.4 - 459958 - - - 2.1554 - 1.988 0.396 - 126.1 1 1 0 0.0041 17 0 0 0 5.99E+05 3.68E+06 - - - 4.6898 0.9974 221125_WJC_METTL3_EV_vs_WT_F06.11830.11830.2 0.117 22-Sep K.SGPSVPVSVQTK.D sp|Q9Y2W2|WBP11_HUMAN 1 1184.6401 0.32 81397 11830 2 1184.640846 593.3273 WW domain-binding protein 11 OS=Homo sapiens OX=9606 GN=WBP11 PE=1 SV=1 8.47 2224.6 - 236219 - - - 0.628 - 1.346 0.251 - 176.5 1 2 0 0.0007 12 0 0 0 2.35E+06 7.41E+06 - - - 1.6765 0.9998 221125_WJC_METTL3_EV_vs_WT_F06.11837.11837.3 1.20E-06 Dec-44 K.LHGVNINVEASK.N "sp|Q9BWF3|RBM4_HUMAN,sp|Q9BQ04|RBM4B_HUMAN,tr|E9PM61|E9PM61_HUMAN,tr|D6R9K7|D6R9K7_HUMAN,tr|J3QRR5|J3QRR5_HUMAN,tr|E9PB51|E9PB51_HUMAN,tr|U3KQD5|U3KQD5_HUMAN,tr|E9PLB0|E9PLB0_HUMAN" 8 1279.6885 1.53 81402 11837 3 1279.690764 427.5701 RNA-binding protein 4 OS=Homo sapiens OX=9606 GN=RBM4 PE=1 SV=1 6.75 2225.5 - 3.72E+06 - - - 1.8083 - 2.71 0.327 - 325.8 1 2 0 0.0023 12 0 0 0 1.34E+09 8.72E+08 - - - 4.9485 0.9999 221125_WJC_METTL3_EV_vs_WT_F06.11838.11838.3 1.72E-05 13/44 K.LHGVNINVEASK[136.11].N "sp|Q9BWF3|RBM4_HUMAN,sp|Q9BQ04|RBM4B_HUMAN,tr|E9PM61|E9PM61_HUMAN,tr|D6R9K7|D6R9K7_HUMAN,tr|J3QRR5|J3QRR5_HUMAN,tr|E9PB51|E9PB51_HUMAN,tr|U3KQD5|U3KQD5_HUMAN,tr|E9PLB0|E9PLB0_HUMAN" 8 1287.7026 1.53 81403 11838 3 1287.705676 430.2415 RNA-binding protein 4 OS=Homo sapiens OX=9606 GN=RBM4 PE=1 SV=1 6.75 2225.5 - 3.13E+06 - - - 2.3499 - 2.966 0.461 - 428 1 2 0 0.003 12 0 0 0 1.34E+09 8.72E+08 - - - 6.6925 0.9991 221125_WJC_METTL3_EV_vs_WT_F06.11842.11842.3 0.000173 Dec-48 R.LKNTLTQTTENLR.R sp|P15924|DESP_HUMAN 1 1530.8366 999 81407 11842 3 1530.838429 511.2861 Desmoplakin OS=Homo sapiens OX=9606 GN=DSP PE=1 SV=3 8.75 2225.9 - 1.23E+06 - - - 1.2144 - 2.114 0.376 - 171.5 1 2 1 0.0019 13 0 0 0 3.92E+07 0.00E+00 - - - 4.7611 0.9993 221125_WJC_METTL3_EV_vs_WT_F06.11843.11843.3 8.20E-06 Nov-48 K.EFTTGENFKGPDR.E sp|Q6ZRP7|QSOX2_HUMAN 1 1496.6896 1.22 81408 11843 3 1496.692475 499.9038 Sulfhydryl oxidase 2 OS=Homo sapiens OX=9606 GN=QSOX2 PE=1 SV=3 4.68 2225.9 - 1.01E+06 - - - 1.9396 - 2.375 0.402 - 139.2 1 2 1 0.0029 13 0 0 0 4.20E+07 3.43E+07 - - - 5.3664 1 221125_WJC_METTL3_EV_vs_WT_F06.11845.11845.2 1.50E-08 18/22 K.TVFAEHISDEC[160.03]K[136.11].R "sp|P39023|RL3_HUMAN,tr|G5E9G0|G5E9G0_HUMAN,tr|H7C3M2|H7C3M2_HUMAN,tr|F8WCR1|F8WCR1_HUMAN,tr|B5MCW2|B5MCW2_HUMAN,tr|H7C422|H7C422_HUMAN" 6 1442.6591 0.88 81410 11845 2 1442.659946 722.3368 60S ribosomal protein L3 OS=Homo sapiens OX=9606 GN=RPL3 PE=1 SV=2 4.65 2226.2 - 796095 - - - 0.5656 - 3.177 0.617 - 1041.3 1 2 0 0.0008 12 0 0 0 6.56E+06 7.44E+06 - - - 6.6394 1 221125_WJC_METTL3_EV_vs_WT_F06.11846.11846.2 1.12E-11 17/22 K.TVFAEHISDEC[160.03]K.R "sp|P39023|RL3_HUMAN,tr|G5E9G0|G5E9G0_HUMAN,tr|H7C3M2|H7C3M2_HUMAN,tr|F8WCR1|F8WCR1_HUMAN,tr|B5MCW2|B5MCW2_HUMAN,tr|H7C422|H7C422_HUMAN" 6 1434.6449 0.88 81411 11846 2 1434.649218 718.3297 60S ribosomal protein L3 OS=Homo sapiens OX=9606 GN=RPL3 PE=1 SV=2 4.65 2226.3 - 747552 - - - 2.9889 - 3.165 0.661 - 960.1 1 2 0 0.0043 12 0 0 0 6.56E+06 7.44E+06 - - - 6.9533 1 221125_WJC_METTL3_EV_vs_WT_F06.11848.11848.2 2.92E-07 16/22 K.LHGVNINVEASK.N "sp|Q9BWF3|RBM4_HUMAN,sp|Q9BQ04|RBM4B_HUMAN,tr|E9PM61|E9PM61_HUMAN,tr|D6R9K7|D6R9K7_HUMAN,tr|J3QRR5|J3QRR5_HUMAN,tr|E9PB51|E9PB51_HUMAN,tr|U3KQD5|U3KQD5_HUMAN,tr|E9PLB0|E9PLB0_HUMAN" 8 1279.6885 -1 81413 11848 2 1279.691721 640.8515 RNA-binding protein 4 OS=Homo sapiens OX=9606 GN=RBM4 PE=1 SV=1 6.75 2226.6 - 479232 - - - 2.5561 - 3.083 0.607 - 846.4 1 2 0 0.0033 12 0 0 0 0.00E+00 0.00E+00 - - - 6.4857 0.995 221125_WJC_METTL3_EV_vs_WT_F06.11850.11850.2 8.65E-05 18-Dec V.FAEHISDEC[160.03]K.R "sp|P39023|RL3_HUMAN,tr|G5E9G0|G5E9G0_HUMAN,tr|H7C3M2|H7C3M2_HUMAN,tr|F8WCR1|F8WCR1_HUMAN,tr|B5MCW2|B5MCW2_HUMAN,tr|H7C422|H7C422_HUMAN" 6 1234.5288 1.61 81414 11850 2 1234.529105 618.2717 60S ribosomal protein L3 OS=Homo sapiens OX=9606 GN=RPL3 PE=1 SV=2 4.65 2226.8 - 235845 - - - 0.2163 - 2.506 0.556 - 710.8 1 1 0 0.0003 10 0 0 0 2.25E+06 1.39E+06 - - - 5.7119 0.9938 221125_WJC_METTL3_EV_vs_WT_F06.11852.11852.2 0.000312 18-Sep V.FAEHISDEC[160.03]K[136.11].R "sp|P39023|RL3_HUMAN,tr|G5E9G0|G5E9G0_HUMAN,tr|H7C3M2|H7C3M2_HUMAN,tr|F8WCR1|F8WCR1_HUMAN,tr|B5MCW2|B5MCW2_HUMAN,tr|H7C422|H7C422_HUMAN" 6 1242.543 1.61 81416 11852 2 1242.542879 622.2788 60S ribosomal protein L3 OS=Homo sapiens OX=9606 GN=RPL3 PE=1 SV=2 4.65 2227.1 - 181599 - - - -0.128 - 2.205 0.526 - 266.2 1 1 0 -0.0002 10 0 0 0 2.25E+06 1.39E+06 - - - 5.1331 0.9992 221125_WJC_METTL3_EV_vs_WT_F06.11853.11853.2 0.0222 24-Oct R.KETPPPLVPPAAR.E sp|Q9BQA1|MEP50_HUMAN 1 1371.7874 8.23 81417 11853 2 1371.78943 686.901 Methylosome protein 50 OS=Homo sapiens OX=9606 GN=WDR77 PE=1 SV=1 8.75 2227.2 - 177307 - - - 1.4543 - 1.82 0.331 - 251.1 1 2 0 0.002 13 0 0 0 1.47E+07 1.79E+06 - - - 3.0221 0.9974 221125_WJC_METTL3_EV_vs_WT_F06.11856.11856.3 0.0209 Nov-36 R.EKLQEEMLQR.E "sp|P08670|VIME_HUMAN,tr|B0YJC4|B0YJC4_HUMAN" 2 1302.6602 1.49 81418 11856 3 1302.661448 435.2273 Vimentin OS=Homo sapiens OX=9606 GN=VIM PE=1 SV=4 4.79 2227.6 - 1.91E+07 - - - 0.9688 - 1.888 0.304 - 248 1 2 1 0.0013 10 0 0 0 1.52E+08 1.02E+08 - - - 3.7849 0.9948 221125_WJC_METTL3_EV_vs_WT_F06.11857.11857.2 2.85E-06 13/22 F.SSGGFSGGSFSR.G "sp|P13645|K1C10_HUMAN,tr|A0A1B0GVI3|A0A1B0GVI3_HUMAN" 2 1131.4945 999 81419 11857 2 1131.49477 566.7545 "Keratin, type I cytoskeletal 10 OS=Homo sapiens OX=9606 GN=KRT10 PE=1 SV=6" 9.47 2227.6 - 5.56E+06 - - - 0.2377 - 2.417 0.578 - 589 1 1 0 0.0003 12 0 0 0 6.18E+07 0.00E+00 - - - 5.6321 0.9907 221125_WJC_METTL3_EV_vs_WT_F06.11858.11858.3 0.164 Nov-44 R.DGVIEASINHEK.G sp|O43242|PSMD3_HUMAN 1 1310.6466 0.38 81420 11858 3 1310.641692 437.8895 26S proteasome non-ATPase regulatory subunit 3 OS=Homo sapiens OX=9606 GN=PSMD3 PE=1 SV=2 4.65 2227.7 - 3.62E+06 - - - -3.7783 - 2.017 0.232 - 91.6 1 2 0 -0.005 12 0 0 0 2.58E+07 6.83E+07 - - - 3.07 0.9977 221125_WJC_METTL3_EV_vs_WT_F06.11859.11859.2 0.0257 22-Sep K.EYSGFAGVSRPR.G "sp|Q9NYF8|BCLF1_HUMAN,tr|H0YF63|H0YF63_HUMAN,tr|E9PK91|E9PK91_HUMAN,tr|H0YF14|H0YF14_HUMAN" 4 1324.6524 1.81 81421 11859 2 1324.652324 663.3335 Bcl-2-associated transcription factor 1 OS=Homo sapiens OX=9606 GN=BCLAF1 PE=1 SV=2 8.85 2227.7 - 3.16E+06 - - - -0.0559 - 1.408 0.236 - 83.4 1 2 0 -0.0001 12 0 0 0 1.12E+08 6.16E+07 - - - 1.6844 0.9999 221125_WJC_METTL3_EV_vs_WT_F06.11861.11861.3 0.000238 Aug-44 K.SMYEEEINETRR.K "sp|P20700|LMNB1_HUMAN,tr|E9PBF6|E9PBF6_HUMAN,tr|A0A0D9SFE5|A0A0D9SFE5_HUMAN" 3 1555.6937 0.86 81423 11861 3 1555.693661 519.5718 Lamin-B1 OS=Homo sapiens OX=9606 GN=LMNB1 PE=1 SV=2 4.49 2227.8 - 1.98E+06 - - - -0.0064 - 1.662 0.486 - 90.5 1 2 0 0 12 0 0 0 1.30E+07 1.51E+07 - - - 5.3666 0.9976 221125_WJC_METTL3_EV_vs_WT_F06.11862.11862.2 0.114 12-Jul K.SSFSITR.E "sp|Q9Y2W1|TR150_HUMAN,tr|A0A3B3ITZ9|A0A3B3ITZ9_HUMAN" 2 796.4079 1.68 81424 11862 2 796.408176 399.2112 Thyroid hormone receptor-associated protein 3 OS=Homo sapiens OX=9606 GN=THRAP3 PE=1 SV=2 9.47 2227.9 - 1.79E+06 - - - 0.324 - 1.379 0.219 - 219.3 1 2 0 0.0003 7 0 0 0 1.00E+07 5.95E+06 - - - 1.6767 1 221125_WJC_METTL3_EV_vs_WT_F06.11863.11863.2 1.79E-09 22-Dec N.SGYTQSQFSAPR[166.11].D "sp|Q14444|CAPR1_HUMAN,tr|G3V153|G3V153_HUMAN" 2 1337.6239 0.62 81425 11863 2 1337.624214 669.8193 Caprin-1 OS=Homo sapiens OX=9606 GN=CAPRIN1 PE=1 SV=2 8.46 2228 - 1.69E+06 - - - 0.1981 - 2.239 0.639 - 446.5 1 1 0 0.0003 12 0 0 0 1.00E+07 1.62E+07 - - - 5.8814 0.9999 221125_WJC_METTL3_EV_vs_WT_F06.11864.11864.2 3.09E-05 16/22 K.LHGVNINVEASK[136.11].N "sp|Q9BWF3|RBM4_HUMAN,sp|Q9BQ04|RBM4B_HUMAN,tr|E9PM61|E9PM61_HUMAN,tr|D6R9K7|D6R9K7_HUMAN,tr|J3QRR5|J3QRR5_HUMAN,tr|E9PB51|E9PB51_HUMAN,tr|U3KQD5|U3KQD5_HUMAN,tr|E9PLB0|E9PLB0_HUMAN" 8 1287.7026 1.48 81426 11864 2 1287.703251 644.8586 RNA-binding protein 4 OS=Homo sapiens OX=9606 GN=RBM4 PE=1 SV=1 6.75 2228.1 - 1.52E+06 - - - 0.4667 - 2.898 0.512 - 835.9 1 2 0 0.0006 12 0 0 0 2.79E+08 1.88E+08 - - - 5.6221 0.9994 221125_WJC_METTL3_EV_vs_WT_F06.11865.11865.3 0.118 Dec-44 K.VSGSQIVDIDK[136.11]R[166.11].K "sp|P60520|GBRL2_HUMAN,tr|H3BSM5|H3BSM5_HUMAN" 2 1333.732 1.84 81427 11865 3 1333.731454 445.5846 Gamma-aminobutyric acid receptor-associated protein-like 2 OS=Homo sapiens OX=9606 GN=GABARAPL2 PE=1 SV=1 5.93 2228.1 - 1.48E+06 - - - -0.4461 - 2.042 0.281 - 233.1 1 2 0 -0.0006 12 0 0 0 1.94E+07 1.05E+07 - - - 3.6516 1 221125_WJC_METTL3_EV_vs_WT_F06.11867.11867.3 1.92E-05 15/48 R.K[136.11]ETPPPLVPPAAR[166.11].E sp|Q9BQA1|MEP50_HUMAN 1 1389.8099 3.48 81429 11867 3 1389.810722 464.2772 Methylosome protein 50 OS=Homo sapiens OX=9606 GN=WDR77 PE=1 SV=1 8.75 2228.3 - 1.35E+06 - - - 0.5879 - 3.087 0.509 - 321.7 1 2 0 0.0008 13 0 0 0 1.25E+08 3.58E+07 - - - 7.2708 1 221125_WJC_METTL3_EV_vs_WT_F06.11868.11868.2 6.01E-10 16/28 L.VSWADGGQHSSIHPA.- "sp|O00746|NDKM_HUMAN,tr|Q4TT34|Q4TT34_HUMAN,tr|A0A087WVT9|A0A087WVT9_HUMAN" 3 1547.7117 - 81430 11868 2 1547.712278 774.8631 "Nucleoside diphosphate kinase, mitochondrial OS=Homo sapiens OX=9606 GN=NME4 PE=1 SV=1" 5.97 2228.5 - 1.24E+06 - - - 0.3709 - 2.971 0.661 - 475.7 1 1 0 0.0006 15 0 0 0 - - - - - 6.6001 0.9992 221125_WJC_METTL3_EV_vs_WT_F06.11869.11869.3 0.0372 Nov-40 K.KPVIVFVPSRK.Q sp|O75643|U520_HUMAN 1 1268.7969 1.16 81431 11869 3 1268.795634 423.9396 U5 small nuclear ribonucleoprotein 200 kDa helicase OS=Homo sapiens OX=9606 GN=SNRNP200 PE=1 SV=2 11.17 2228.5 - 1.18E+06 - - - -0.9805 - 1.978 0.265 - 217.3 1 2 0 -0.0012 11 0 0 0 1.26E+07 1.09E+07 - - - 3.4318 0.9998 221125_WJC_METTL3_EV_vs_WT_F06.11873.11873.3 0.000259 Nov-60 K.NAVSVHSNLNSEAVMK[136.11].S "sp|Q5QJE6|TDIF2_HUMAN,tr|J3KP30|J3KP30_HUMAN" 2 1706.8501 1.72 81435 11873 3 1706.848227 569.9573 Deoxynucleotidyltransferase terminal-interacting protein 2 OS=Homo sapiens OX=9606 GN=DNTTIP2 PE=1 SV=2 6.75 2228.9 - 815894 - - - -1.1085 - 2.187 0.378 - 145.3 1 2 0 -0.0019 16 0 0 0 6.66E+06 3.87E+06 - - - 4.7617 1 221125_WJC_METTL3_EV_vs_WT_F06.11875.11875.2 1.90E-05 14/24 R.LKNTLTQTTENLR.R sp|P15924|DESP_HUMAN 1 1530.8366 999 81437 11875 2 1530.837588 766.4256 Desmoplakin OS=Homo sapiens OX=9606 GN=DSP PE=1 SV=3 8.75 2229.1 - 652758 - - - 0.665 - 3.083 0.533 - 548.6 1 2 1 0.001 13 0 0 0 8.89E+06 0.00E+00 - - - 5.8671 0.8846 221125_WJC_METTL3_EV_vs_WT_F06.11880.11880.3 0.0265 Nov-44 L.LAGASTHFPSKR.L "sp|Q96LP6|CL042_HUMAN,tr|F8VV63|F8VV63_HUMAN" 2 1270.6782 0.04 81441 11880 3 1270.677221 424.5667 Uncharacterized protein C12orf42 OS=Homo sapiens OX=9606 GN=C12orf42 PE=2 SV=2 11 2229.6 - 1.06E+06 - - - -0.7854 - 1.921 0.252 - 191.2 1 1 0 -0.001 12 0 0 0 2.63E+07 6.75E+08 - - - 3.1589 0.9937 221125_WJC_METTL3_EV_vs_WT_F06.11881.11881.2 0.00107 22-Dec R.DGVIEASINHEK.G sp|O43242|PSMD3_HUMAN 1 1310.6466 1.08 81442 11881 2 1310.641907 656.3306 26S proteasome non-ATPase regulatory subunit 3 OS=Homo sapiens OX=9606 GN=PSMD3 PE=1 SV=2 4.65 2229.7 - 931306 - - - -3.6142 - 2.107 0.198 - 331.4 1 2 0 -0.0047 12 0 0 0 6.64E+06 6.12E+06 - - - 2.4629 0.9999 221125_WJC_METTL3_EV_vs_WT_F06.11883.11883.3 0.000299 13/40 R.K[136.11]IHVTPLIPGK[136.11].S sp|Q9H0L4|CSTFT_HUMAN 1 1217.7831 1.52 81444 11883 3 1217.785679 406.935 Cleavage stimulation factor subunit 2 tau variant OS=Homo sapiens OX=9606 GN=CSTF2T PE=1 SV=1 10 2229.9 - 588690 - - - 2.135 - 2.205 0.439 - 186.3 1 2 0 0.0026 11 0 0 0 7.34E+06 4.84E+06 - - - 5.68 0.9903 221125_WJC_METTL3_EV_vs_WT_F06.11887.11887.2 9.64E-07 13/26 V.SWADGGQHSSIHPA.- "sp|O00746|NDKM_HUMAN,tr|Q4TT34|Q4TT34_HUMAN,tr|A0A087WVT9|A0A087WVT9_HUMAN" 3 1448.6433 - 81448 11887 2 1448.644752 725.3289 "Nucleoside diphosphate kinase, mitochondrial OS=Homo sapiens OX=9606 GN=NME4 PE=1 SV=1" 5.92 2230.4 - 386057 - - - 1.0092 - 2.687 0.448 - 327.4 1 1 0 0.0015 14 0 0 0 - - - - - 4.8299 0.9815 221125_WJC_METTL3_EV_vs_WT_F06.11888.11888.2 8.89E-06 20-Oct E.YSGFAGVSR[166.11]PR[166.11].G "sp|Q9NYF8|BCLF1_HUMAN,tr|H0YF63|H0YF63_HUMAN,tr|E9PK91|E9PK91_HUMAN,tr|H0YF14|H0YF14_HUMAN" 4 1215.6263 3.1 81449 11888 2 1215.627012 608.8204 Bcl-2-associated transcription factor 1 OS=Homo sapiens OX=9606 GN=BCLAF1 PE=1 SV=2 10.84 2230.6 - 373234 - - - 0.5487 - 1.723 0.424 - 161.4 1 1 0 0.0007 11 0 0 0 8.42E+06 2.72E+06 - - - 3.6443 0.9946 221125_WJC_METTL3_EV_vs_WT_F06.11889.11889.2 4.23E-07 26-Dec Y.EIDAC[160.03]MDSEAPGSK[136.11].D "sp|Q86U44|MTA70_HUMAN,tr|H0YFV6|H0YFV6_HUMAN" 2 1516.6265 0.001 81450 11889 2 1516.625636 759.3205 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 3.92 2230.7 - 337190 - - - -0.5756 - 2.207 0.616 - 297.3 1 1 0 -0.0009 14 0 0 0 0.00E+00 6.63E+06 - - - 5.5771 1 221125_WJC_METTL3_EV_vs_WT_F06.11890.11890.2 4.78E-08 13/28 R.ADLNQGIGEPQSPSR[166.11].R sp|Q96C19|EFHD2_HUMAN 1 1577.7673 1.25 81451 11890 2 1577.768137 789.8909 EF-hand domain-containing protein D2 OS=Homo sapiens OX=9606 GN=EFHD2 PE=1 SV=1 4.37 2230.8 - 323887 - - - 0.5191 - 2.894 0.6 - 459.1 1 2 0 0.0008 15 0 0 0 7.17E+06 5.75E+06 - - - 6.0849 0.9998 221125_WJC_METTL3_EV_vs_WT_F06.11892.11892.2 1.65E-06 26-Dec K.GTDTQTPAVLSPSK[136.11].T sp|P46087|NOP2_HUMAN 1 1408.7289 1.17 81453 11892 2 1408.73048 705.3717 Probable 28S rRNA (cytosine(4447)-C(5))-methyltransferase OS=Homo sapiens OX=9606 GN=NOP2 PE=1 SV=2 5.84 2231.1 - 260902 - - - 1.1045 - 2.525 0.496 - 551.6 1 2 0 0.0016 14 0 0 0 1.76E+07 1.50E+07 - - - 5.0283 1 221125_WJC_METTL3_EV_vs_WT_F06.11895.11895.3 4.69E-06 Dec-44 R.K[136.11]AEEELGELEAK[136.11].L sp|Q9UQE7|SMC3_HUMAN 1 1360.7057 9.13 81455 11895 3 1360.70518 454.5758 Structural maintenance of chromosomes protein 3 OS=Homo sapiens OX=9606 GN=SMC3 PE=1 SV=2 4.33 2231.5 - 4.17E+06 - - - -0.3645 - 2.657 0.502 - 350.6 1 2 0 -0.0005 12 0 0 0 3.89E+08 4.26E+07 - - - 6.8453 1 221125_WJC_METTL3_EV_vs_WT_F06.11896.11896.3 1.65E-05 18/48 R.KETPPPLVPPAAR.E sp|Q9BQA1|MEP50_HUMAN 1 1371.7874 3.5 81456 11896 3 1371.787196 458.2698 Methylosome protein 50 OS=Homo sapiens OX=9606 GN=WDR77 PE=1 SV=1 8.75 2231.5 - 6.52E+06 - - - -0.1742 - 2.739 0.479 - 516.1 1 2 0 -0.0002 13 0 0 0 1.26E+08 3.59E+07 - - - 6.6122 0.9999 221125_WJC_METTL3_EV_vs_WT_F06.11897.11897.2 0.00108 14/24 R.GSENGNEGSLLER.E sp|Q5JSZ5|PRC2B_HUMAN 1 1360.6219 1.8 81457 11897 2 1360.62246 681.3182 Protein PRRC2B OS=Homo sapiens OX=9606 GN=PRRC2B PE=1 SV=2 4.25 2231.6 - 1.83E+06 - - - 0.4219 - 2.551 0.563 - 777.7 1 2 0 0.0006 13 0 0 0 2.43E+07 1.35E+07 - - - 5.6027 0.9993 221125_WJC_METTL3_EV_vs_WT_F06.11898.11898.3 0.000248 Dec-48 K.EFTTGENFK[136.11]GPDR[166.11].E sp|Q6ZRP7|QSOX2_HUMAN 1 1514.712 1.35 81458 11898 3 1514.711309 505.9113 Sulfhydryl oxidase 2 OS=Homo sapiens OX=9606 GN=QSOX2 PE=1 SV=3 4.68 2231.6 - 1.73E+06 - - - -0.4839 - 2.145 0.373 - 168.5 1 2 1 -0.0007 13 0 0 0 3.09E+07 2.29E+07 - - - 4.7675 0.9998 221125_WJC_METTL3_EV_vs_WT_F06.11899.11899.3 0.000165 Oct-32 R.K[136.11]QVFDQYVK[136.11].T "sp|O14776|TCRG1_HUMAN,tr|A0A7P0T8N8|A0A7P0T8N8_HUMAN,tr|G3V220|G3V220_HUMAN" 3 1169.6416 0.72 81459 11899 3 1169.641 390.8878 Transcription elongation regulator 1 OS=Homo sapiens OX=9606 GN=TCERG1 PE=1 SV=2 8.5 2231.7 - 1.22E+06 - - - -0.4779 - 1.801 0.396 - 157.2 1 2 0 -0.0006 9 0 0 0 1.11E+07 1.54E+07 - - - 4.728 1 221125_WJC_METTL3_EV_vs_WT_F06.11901.11901.2 1.19E-06 13/24 R.DQTPDENDQVIVK.L sp|Q9NZI8|IF2B1_HUMAN 1 1499.7104 1.69 81461 11901 2 1499.709702 750.8625 Insulin-like growth factor 2 mRNA-binding protein 1 OS=Homo sapiens OX=9606 GN=IGF2BP1 PE=1 SV=2 3.84 2232 - 1.15E+06 - - - -0.4434 - 2.332 0.647 - 464.2 1 2 0 -0.0007 13 0 0 0 7.59E+08 4.50E+08 - - - 5.9927 1 221125_WJC_METTL3_EV_vs_WT_F06.11902.11902.2 1.47E-06 24-Dec R.DQTPDENDQVIVK[136.11].L sp|Q9NZI8|IF2B1_HUMAN 1 1507.7246 1.69 81462 11902 2 1507.723228 754.8696 Insulin-like growth factor 2 mRNA-binding protein 1 OS=Homo sapiens OX=9606 GN=IGF2BP1 PE=1 SV=2 3.84 2232.1 - 917629 - - - -0.8881 - 2.514 0.59 - 365.3 1 2 0 -0.0013 13 0 0 0 7.59E+08 4.50E+08 - - - 5.7643 1 221125_WJC_METTL3_EV_vs_WT_F06.11904.11904.2 4.80E-05 15/28 R.ADLNQGIGEPQSPSR.R sp|Q96C19|EFHD2_HUMAN 1 1567.759 1.25 81464 11904 2 1567.759094 784.8868 EF-hand domain-containing protein D2 OS=Homo sapiens OX=9606 GN=EFHD2 PE=1 SV=1 4.37 2232.4 - 678768 - - - 0.0293 - 3.055 0.592 - 635.9 1 2 0 0 15 0 0 0 7.17E+06 5.75E+06 - - - 6.1592 1 221125_WJC_METTL3_EV_vs_WT_F06.11905.11905.3 2.05E-09 17/60 R.AVTPVPTKTEEVSNLK.T "sp|Q6PKG0|LARP1_HUMAN,tr|A0A0B4J210|A0A0B4J210_HUMAN,tr|H0YBW1|H0YBW1_HUMAN,tr|E5RH50|E5RH50_HUMAN" 4 1711.9356 1.4 81465 11905 3 1711.935722 571.6525 La-related protein 1 OS=Homo sapiens OX=9606 GN=LARP1 PE=1 SV=2 6.19 2232.5 - 568328 - - - 0.0619 - 3.209 0.595 - 424.3 1 2 1 0.0001 16 0 0 0 2.77E+07 1.97E+07 - - - 8.1653 1 221125_WJC_METTL3_EV_vs_WT_F06.11907.11907.2 1.36E-05 13/16 R.K[136.11]QVFDQYVK[136.11].T "sp|O14776|TCRG1_HUMAN,tr|A0A7P0T8N8|A0A7P0T8N8_HUMAN,tr|G3V220|G3V220_HUMAN" 3 1169.6416 0.86 81467 11907 2 1169.643713 585.8281 Transcription elongation regulator 1 OS=Homo sapiens OX=9606 GN=TCERG1 PE=1 SV=2 8.5 2232.7 - 429448 - - - 1.8416 - 2.864 0.54 - 574.5 1 2 0 0.0022 9 0 0 0 5.62E+06 6.52E+06 - - - 6.0729 0.9999 221125_WJC_METTL3_EV_vs_WT_F06.11910.11910.3 1.70E-06 18/60 R.AVTPVPTK[136.11]TEEVSNLK[136.11].T "sp|Q6PKG0|LARP1_HUMAN,tr|A0A0B4J210|A0A0B4J210_HUMAN,tr|H0YBW1|H0YBW1_HUMAN,tr|E5RH50|E5RH50_HUMAN" 4 1727.964 1.43 81468 11910 3 1727.964362 576.9953 La-related protein 1 OS=Homo sapiens OX=9606 GN=LARP1 PE=1 SV=2 6.19 2233.1 - 1.27E+06 - - - 0.2002 - 3.507 0.529 - 416.4 1 2 1 0.0003 16 0 0 0 2.81E+07 1.97E+07 - - - 7.6573 1 221125_WJC_METTL3_EV_vs_WT_F06.11911.11911.3 1.43E-05 22/52 R.QDPQSTAAATVLK[136.11]R[166.11].A "sp|Q8WV92|MITD1_HUMAN,tr|F8WED5|F8WED5_HUMAN,tr|B8ZZL5|B8ZZL5_HUMAN,tr|A0A1W2PP14|A0A1W2PP14_HUMAN" 4 1502.8172 1.28 81469 11911 3 1502.818258 501.9463 MIT domain-containing protein 1 OS=Homo sapiens OX=9606 GN=MITD1 PE=1 SV=1 8.75 2233.2 - 944753 - - - 0.72 - 4.009 0.588 - 1157.6 1 2 0 0.0011 14 0 0 0 2.54E+07 1.98E+07 - - - 8.7854 1 221125_WJC_METTL3_EV_vs_WT_F06.11915.11915.3 3.87E-11 21/56 R.LPEYTVTQESGPAHR.K "sp|Q15633|TRBP2_HUMAN,tr|F8VW32|F8VW32_HUMAN,tr|F8VZ57|F8VZ57_HUMAN,tr|F8VSA1|F8VSA1_HUMAN,tr|H3BV98|H3BV98_HUMAN" 5 1683.8216 2.41 81473 11915 3 1683.819137 562.2812 RISC-loading complex subunit TARBP2 OS=Homo sapiens OX=9606 GN=TARBP2 PE=1 SV=3 5.4 2233.5 - 1.16E+06 - - - -1.4918 - 3.943 0.554 - 783.3 1 2 0 -0.0025 15 0 0 0 3.59E+07 1.49E+07 - - - 8.2958 0.9999 221125_WJC_METTL3_EV_vs_WT_F06.11916.11916.2 2.71E-06 26-Oct K.GTDTQTPAVLSPSK.T sp|P46087|NOP2_HUMAN 1 1400.7147 0.94 81474 11916 2 1400.714837 701.3646 Probable 28S rRNA (cytosine(4447)-C(5))-methyltransferase OS=Homo sapiens OX=9606 GN=NOP2 PE=1 SV=2 5.84 2233.7 - 357092 - - - 0.0807 - 2.371 0.521 - 333.6 1 2 0 0.0001 14 0 0 0 1.35E+07 1.44E+07 - - - 5.0555 0.9999 221125_WJC_METTL3_EV_vs_WT_F06.11917.11917.2 2.48E-07 26-Oct K.SNEPEGQVEPGALR.Y "sp|O75147|OBSL1_HUMAN,tr|A6NN50|A6NN50_HUMAN,tr|A8MSZ8|A8MSZ8_HUMAN" 3 1481.711 0.99 81475 11917 2 1481.711399 741.8628 Obscurin-like protein 1 OS=Homo sapiens OX=9606 GN=OBSL1 PE=1 SV=4 4.25 2233.8 - 297792 - - - 0.245 - 2.295 0.528 - 257.6 1 2 0 0.0004 14 0 0 0 4.28E+06 4.33E+06 - - - 5.0254 0.9975 221125_WJC_METTL3_EV_vs_WT_F06.11920.11920.3 5.05E-05 13/56 L.SNLPHSGYSDSAVLK.L "sp|P43243|MATR3_HUMAN,tr|B3KM87|B3KM87_HUMAN,tr|A8MXP9|A8MXP9_HUMAN,tr|D6RBK5|D6RBK5_HUMAN,tr|A0A0R4J2E8|A0A0R4J2E8_HUMAN,tr|H0Y8T4|H0Y8T4_HUMAN,tr|D6REM6|D6REM6_HUMAN" 7 1573.7736 1.47 81476 11920 3 1573.772581 525.5985 Matrin-3 OS=Homo sapiens OX=9606 GN=MATR3 PE=1 SV=2 6.46 2234.2 - 5.02E+06 - - - -0.6704 - 2.733 0.505 - 221.3 1 1 0 -0.0011 15 0 0 0 6.79E+07 4.63E+07 - - - 6.7934 1 221125_WJC_METTL3_EV_vs_WT_F06.11922.11922.3 8.61E-11 22/52 R.QDPQSTAAATVLKR.A "sp|Q8WV92|MITD1_HUMAN,tr|F8WED5|F8WED5_HUMAN,tr|B8ZZL5|B8ZZL5_HUMAN,tr|A0A1W2PP14|A0A1W2PP14_HUMAN" 4 1484.7947 1.27 81478 11922 3 1484.794341 495.9388 MIT domain-containing protein 1 OS=Homo sapiens OX=9606 GN=MITD1 PE=1 SV=1 8.75 2234.3 - 1.21E+06 - - - -0.2458 - 3.699 0.657 - 933.3 1 2 0 -0.0004 14 0 0 0 2.65E+07 2.08E+07 - - - 9.341 1 221125_WJC_METTL3_EV_vs_WT_F06.11924.11924.2 1.87E-08 15/32 K.AAAAAWEEPSSGNGTAR[166.11].A sp|Q9P258|RCC2_HUMAN 1 1654.7575 0.42 81480 11924 2 1654.764203 828.386 Protein RCC2 OS=Homo sapiens OX=9606 GN=RCC2 PE=1 SV=2 4.53 2234.6 - 843462 - - - 4.0616 - 3.164 0.559 - 640.8 1 2 0 0.0067 17 0 0 0 1.56E+07 3.76E+07 - - - 5.9995 1 221125_WJC_METTL3_EV_vs_WT_F06.11925.11925.3 5.78E-05 16/48 R.KEPC[160.03]VLGVDEAGR.G "sp|O75792|RNH2A_HUMAN,tr|A0A2R8Y606|A0A2R8Y606_HUMAN,tr|A0A2R8Y658|A0A2R8Y658_HUMAN" 3 1428.7031 1.72 81481 11925 3 1428.704876 477.2416 Ribonuclease H2 subunit A OS=Homo sapiens OX=9606 GN=RNASEH2A PE=1 SV=2 4.68 2234.7 - 617585 - - - 1.2333 - 3.029 0.478 - 486.2 1 2 0 0.0018 13 0 0 0 6.78E+07 3.94E+07 - - - 6.8735 0.9998 221125_WJC_METTL3_EV_vs_WT_F06.11930.11930.3 0.00259 Oct-40 R.DVKPSNVLINK.E sp|P46734|MP2K3_HUMAN 1 1225.703 0.83 81484 11930 3 1225.703108 409.575 Dual specificity mitogen-activated protein kinase kinase 3 OS=Homo sapiens OX=9606 GN=MAP2K3 PE=1 SV=2 8.59 2235.4 - 968881 - - - 0.0579 - 1.983 0.357 - 121.4 1 2 0 0.0001 11 0 0 0 8.35E+06 1.00E+07 - - - 4.465 1 221125_WJC_METTL3_EV_vs_WT_F06.11932.11932.3 7.25E-07 15/48 R.K[136.11]EPC[160.03]VLGVDEAGR[166.11].G "sp|O75792|RNH2A_HUMAN,tr|A0A2R8Y606|A0A2R8Y606_HUMAN,tr|A0A2R8Y658|A0A2R8Y658_HUMAN" 3 1446.7256 1.72 81486 11932 3 1446.726126 483.2491 Ribonuclease H2 subunit A OS=Homo sapiens OX=9606 GN=RNASEH2A PE=1 SV=2 4.68 2235.6 - 809024 - - - 0.3746 - 3.044 0.558 - 344.4 1 2 0 0.0005 13 0 0 0 6.78E+07 3.94E+07 - - - 7.7791 0.9853 221125_WJC_METTL3_EV_vs_WT_F06.11938.11938.3 0.0721 Sep-40 R.DASNWSTDKLK.T "sp|O95433|AHSA1_HUMAN,tr|G3V3W9|G3V3W9_HUMAN" 2 1263.6095 4.19 81490 11938 3 1263.610817 422.2105 Activator of 90 kDa heat shock protein ATPase homolog 1 OS=Homo sapiens OX=9606 GN=AHSA1 PE=1 SV=1 5.96 2236.4 - 3.00E+06 - - - 1.0177 - 1.416 0.274 - 110 1 2 1 0.0013 11 0 0 0 3.48E+07 8.30E+06 - - - 2.5826 1 221125_WJC_METTL3_EV_vs_WT_F06.11939.11939.3 0.000429 20/64 R.GR[166.11]PGPEGAGPAAGLDVR[166.11].A sp|Q9BXK1|KLF16_HUMAN 1 1595.8283 1.26 81491 11939 3 1595.828737 532.95 Krueppel-like factor 16 OS=Homo sapiens OX=9606 GN=KLF16 PE=1 SV=1 6.07 2236.5 - 1.78E+06 - - - 0.2782 - 2.897 0.474 - 285.9 1 2 0 0.0004 17 0 0 0 4.37E+07 3.47E+07 - - - 6.5117 1 221125_WJC_METTL3_EV_vs_WT_F06.11940.11940.3 1.31E-06 18/56 R.LPEYTVTQESGPAHR[166.11].K "sp|Q15633|TRBP2_HUMAN,tr|F8VW32|F8VW32_HUMAN,tr|F8VZ57|F8VZ57_HUMAN,tr|F8VSA1|F8VSA1_HUMAN,tr|H3BV98|H3BV98_HUMAN" 5 1693.8299 2.34 81492 11940 3 1693.830536 565.6172 RISC-loading complex subunit TARBP2 OS=Homo sapiens OX=9606 GN=TARBP2 PE=1 SV=3 5.4 2236.6 - 1.19E+06 - - - 0.3643 - 3.529 0.532 - 586.6 1 2 0 0.0006 15 0 0 0 3.46E+07 1.48E+07 - - - 7.7616 0.9898 221125_WJC_METTL3_EV_vs_WT_F06.11946.11946.2 8.22E-06 13/28 L.SNLPHSGYSDSAVLK[136.11].L "sp|P43243|MATR3_HUMAN,tr|B3KM87|B3KM87_HUMAN,tr|A8MXP9|A8MXP9_HUMAN,tr|D6RBK5|D6RBK5_HUMAN,tr|A0A0R4J2E8|A0A0R4J2E8_HUMAN,tr|H0Y8T4|H0Y8T4_HUMAN,tr|D6REM6|D6REM6_HUMAN" 7 1581.7878 1.05 81498 11946 2 1581.786815 791.9012 Matrin-3 OS=Homo sapiens OX=9606 GN=MATR3 PE=1 SV=2 6.46 2237.3 - 398983 - - - -0.6455 - 2.095 0.478 - 410.1 1 1 0 -0.001 15 0 0 0 3.34E+06 3.19E+06 - - - 4.3894 0.9999 221125_WJC_METTL3_EV_vs_WT_F06.11947.11947.2 1.84E-07 30-Oct R.SAAQPSTSPAEVQSLK.K sp|Q14789|GOGB1_HUMAN 1 1599.8104 12.25 81499 11947 2 1599.811568 800.9125 Golgin subfamily B member 1 OS=Homo sapiens OX=9606 GN=GOLGB1 PE=1 SV=2 5.72 2237.4 - 238405 - - - 0.7207 - 2.144 0.597 - 222.2 1 2 0 0.0012 16 0 0 0 3.18E+06 2.60E+05 - - - 5.3251 0.9978 221125_WJC_METTL3_EV_vs_WT_F06.11949.11949.3 5.31E-10 13/56 L.SNLPHSGYSDSAVLK[136.11].L "sp|P43243|MATR3_HUMAN,tr|B3KM87|B3KM87_HUMAN,tr|A8MXP9|A8MXP9_HUMAN,tr|D6RBK5|D6RBK5_HUMAN,tr|A0A0R4J2E8|A0A0R4J2E8_HUMAN,tr|H0Y8T4|H0Y8T4_HUMAN,tr|D6REM6|D6REM6_HUMAN" 7 1581.7878 1.46 81500 11949 3 1581.788724 528.2699 Matrin-3 OS=Homo sapiens OX=9606 GN=MATR3 PE=1 SV=2 6.46 2237.6 - 4.96E+06 - - - 0.5614 - 2.755 0.523 - 226 1 1 0 0.0009 15 0 0 0 6.79E+07 4.64E+07 - - - 7.0151 0.9951 221125_WJC_METTL3_EV_vs_WT_F06.11951.11951.3 0.0121 Sep-44 K.VDVGK[136.11]DQEFTVK[136.11].S "sp|P21333|FLNA_HUMAN,tr|A0A7P0NMY4|A0A7P0NMY4_HUMAN,tr|Q60FE5|Q60FE5_HUMAN" 3 1379.7267 0.6 81501 11951 3 1379.73112 460.9162 Filamin-A OS=Homo sapiens OX=9606 GN=FLNA PE=1 SV=4 4.56 2237.9 - 1.84E+06 - - - 3.1702 - 2.165 0.333 - 86.7 1 2 1 0.0044 12 0 0 0 1.65E+07 2.75E+07 - - - 4.3924 0.9157 221125_WJC_METTL3_EV_vs_WT_F06.11954.11954.3 0.00113 13/44 F.STSPESPYTHWK.Q "sp|Q99873|ANM1_HUMAN,tr|E9PKG1|E9PKG1_HUMAN" 2 1418.6466 2.89 81504 11954 3 1418.649566 473.8895 Protein arginine N-methyltransferase 1 OS=Homo sapiens OX=9606 GN=PRMT1 PE=1 SV=3 6.47 2238.1 - 1.03E+06 - - - 2.0597 - 2.128 0.296 - 170 1 1 0 0.0029 12 0 0 0 1.50E+07 5.18E+06 - - - 3.9326 0.9999 221125_WJC_METTL3_EV_vs_WT_F06.11955.11955.3 1.93E-06 Dec-36 K.TSEEFVHINR[166.11].L "sp|P50851|LRBA_HUMAN,tr|A0A3B3ISK3|A0A3B3ISK3_HUMAN,tr|E9PEM5|E9PEM5_HUMAN,tr|A0A494BZW2|A0A494BZW2_HUMAN,tr|A0A3B3IU76|A0A3B3IU76_HUMAN,tr|A0A3B3IS13|A0A3B3IS13_HUMAN,tr|A0A494C1L5|A0A494C1L5_HUMAN,tr|H0YAC6|H0YAC6_HUMAN" 8 1240.6076 0.54 81505 11955 3 1240.609096 414.5431 Lipopolysaccharide-responsive and beige-like anchor protein OS=Homo sapiens OX=9606 GN=LRBA PE=1 SV=4 5.37 2238.3 - 871525 - - - 1.23 - 2.328 0.443 - 295.9 1 2 0 0.0015 10 0 0 0 4.58E+06 8.44E+06 - - - 5.9464 0.9988 221125_WJC_METTL3_EV_vs_WT_F06.11956.11956.2 0.00228 20-Nov R.DASNWSTDKLK.T "sp|O95433|AHSA1_HUMAN,tr|G3V3W9|G3V3W9_HUMAN" 2 1263.6095 5.19 81506 11956 2 1263.60922 632.812 Activator of 90 kDa heat shock protein ATPase homolog 1 OS=Homo sapiens OX=9606 GN=AHSA1 PE=1 SV=1 5.96 2238.4 - 722064 - - - -0.2461 - 2.361 0.495 - 513.2 1 2 1 -0.0003 11 0 0 0 1.04E+07 2.00E+06 - - - 5.021 1 221125_WJC_METTL3_EV_vs_WT_F06.11957.11957.3 1.44E-09 23/64 R.ALTEC[160.03]QGAVGLGSK[136.11]PVR[166.11].L sp|Q9NX07|TSAP1_HUMAN 1 1759.937 1.4 81507 11957 3 1759.938982 587.6529 tRNA selenocysteine 1-associated protein 1 OS=Homo sapiens OX=9606 GN=TRNAU1AP PE=1 SV=1 8.27 2238.5 - 642350 - - - 1.1409 - 3.946 0.592 - 861 1 2 0 0.002 17 0 0 0 1.79E+07 1.28E+07 - - - 8.6075 0.9999 221125_WJC_METTL3_EV_vs_WT_F06.11966.11966.3 0.000317 15/44 K.TPIKNEPIDLSK.Q "sp|Q96AV8|E2F7_HUMAN,tr|F8VXV5|F8VXV5_HUMAN,tr|F8VSE7|F8VSE7_HUMAN" 3 1353.7504 0.36 81514 11966 3 1353.751091 452.2574 Transcription factor E2F7 OS=Homo sapiens OX=9606 GN=E2F7 PE=1 SV=3 5.73 2239.5 - 1.80E+06 - - - 0.5245 - 2.896 0.441 - 323.1 1 2 1 0.0007 12 0 0 0 2.83E+07 7.75E+07 - - - 6.4039 1 221125_WJC_METTL3_EV_vs_WT_F06.11968.11968.2 1.38E-07 22-Nov R.EIVHLQAGQC[160.03]GN.Q "sp|P04350|TBB4A_HUMAN,sp|Q9BVA1|TBB2B_HUMAN,sp|P07437|TBB5_HUMAN,sp|Q13509|TBB3_HUMAN,sp|Q13885|TBB2A_HUMAN,sp|P68371|TBB4B_HUMAN,sp|Q9BUF5|TBB6_HUMAN,tr|K7EJZ4|K7EJZ4_HUMAN,tr|M0R2D3|M0R2D3_HUMAN,tr|G3V3W7|G3V3W7_HUMAN,tr|K7EQT3|K7EQT3_HUMAN,tr|K7EN98|K7EN98_HUMAN,tr|M0R2T4|M0R2T4_HUMAN,tr|G3V3R4|G3V3R4_HUMAN,tr|M0R042|M0R042_HUMAN,tr|M0QY85|M0QY85_HUMAN,tr|M0QZL7|M0QZL7_HUMAN,tr|K7ESM5|K7ESM5_HUMAN,tr|G3V5W4|G3V5W4_HUMAN,tr|M0R0X0|M0R0X0_HUMAN,tr|K7ERA8|K7ERA8_HUMAN,tr|M0QYM7|M0QYM7_HUMAN,tr|K7ESQ3|K7ESQ3_HUMAN,tr|G3V4U2|G3V4U2_HUMAN,tr|M0R278|M0R278_HUMAN,tr|K7EL29|K7EL29_HUMAN,tr|M0QY37|M0QY37_HUMAN,tr|G3V2R8|G3V2R8_HUMAN,tr|G3V3J6|G3V3J6_HUMAN,tr|M0QX14|M0QX14_HUMAN,tr|K7EPE5|K7EPE5_HUMAN,tr|G3V2N6|G3V2N6_HUMAN,tr|K7EJ64|K7EJ64_HUMAN" 33 1324.6194 - 81516 11968 2 1324.611438 663.317 Tubulin beta-4A chain OS=Homo sapiens OX=9606 GN=TUBB4A PE=1 SV=2 5.24 2239.7 - 1.38E+06 - - - -5.9987 - 2.351 0.652 - 401.9 1 1 0 -0.0079 12 0 0 0 - - - - - 6.1034 1 221125_WJC_METTL3_EV_vs_WT_F06.11974.11974.2 9.39E-08 20-Dec R.DQDNMQAELNR[166.11].L sp|P33176|KINH_HUMAN 1 1342.5811 1.22 81522 11974 2 1342.581753 672.2978 Kinesin-1 heavy chain OS=Homo sapiens OX=9606 GN=KIF5B PE=1 SV=1 4.03 2240.2 - 552683 - - - 0.4879 - 2.532 0.662 - 713.7 1 2 0 0.0007 11 0 0 0 5.95E+06 4.89E+06 - - - 6.4435 1 221125_WJC_METTL3_EV_vs_WT_F06.11975.11975.2 3.03E-08 26-Dec K.EDLNC[160.03]QEEEDPMNK.L "sp|O75821|EIF3G_HUMAN,tr|K7EL20|K7EL20_HUMAN,tr|K7ENA8|K7ENA8_HUMAN" 3 1749.6822 1.4 81523 11975 2 1749.683286 875.8484 Eukaryotic translation initiation factor 3 subunit G OS=Homo sapiens OX=9606 GN=EIF3G PE=1 SV=2 3.77 2240.4 - 550626 - - - 0.6321 - 2.78 0.74 - 337.6 1 2 0 0.0011 14 0 0 0 9.09E+06 6.48E+06 - - - 7.0721 0.9998 221125_WJC_METTL3_EV_vs_WT_F06.11976.11976.2 6.14E-06 20-Sep R.LNQDQLDAVSK[136.11].Y "sp|Q14444|CAPR1_HUMAN,tr|G3V153|G3V153_HUMAN,tr|E9PLA9|E9PLA9_HUMAN" 3 1237.6394 1.33 81524 11976 2 1237.639659 619.827 Caprin-1 OS=Homo sapiens OX=9606 GN=CAPRIN1 PE=1 SV=2 4.21 2240.5 - 488328 - - - 0.2246 - 2.17 0.403 - 223.6 1 2 0 0.0003 11 0 0 0 8.13E+06 6.11E+06 - - - 4.1133 0.9999 221125_WJC_METTL3_EV_vs_WT_F06.11981.11981.2 2.09E-05 20-Nov R.LNQDQLDAVSK.Y "sp|Q14444|CAPR1_HUMAN,tr|G3V153|G3V153_HUMAN,tr|E9PLA9|E9PLA9_HUMAN" 3 1229.6252 1.38 81529 11981 2 1229.62443 615.8199 Caprin-1 OS=Homo sapiens OX=9606 GN=CAPRIN1 PE=1 SV=2 4.21 2241.1 - 264991 - - - -0.6108 - 2.434 0.442 - 389.3 1 2 0 -0.0008 11 0 0 0 8.43E+06 6.11E+06 - - - 4.7118 1 221125_WJC_METTL3_EV_vs_WT_F06.11985.11985.3 1.82E-09 14/52 R.K[136.11]LDPGSEETQTLVR[166.11].E sp|P26641|EF1G_HUMAN 1 1589.838 1.06 81531 11985 3 1589.840605 530.9533 Elongation factor 1-gamma OS=Homo sapiens OX=9606 GN=EEF1G PE=1 SV=3 4.68 2241.7 - 2.68E+06 - - - 1.6568 - 3.138 0.587 - 392.4 1 2 0 0.0026 14 0 0 0 5.15E+08 4.87E+08 - - - 8.1229 1 221125_WJC_METTL3_EV_vs_WT_F06.11986.11986.3 4.26E-09 20/64 R.GRPGPEGAGPAAGLDVR.A sp|Q9BXK1|KLF16_HUMAN 1 1575.8118 1.47 81532 11986 3 1575.816117 526.2779 Krueppel-like factor 16 OS=Homo sapiens OX=9606 GN=KLF16 PE=1 SV=1 6.07 2241.8 - 2.57E+06 - - - 2.7694 - 3.847 0.542 - 517.5 1 2 0 0.0044 17 0 0 0 4.64E+07 3.14E+07 - - - 7.9852 0.9454 221125_WJC_METTL3_EV_vs_WT_F06.11990.11990.3 0.00109 Sep-64 R.MVVNEGSDGGQSVYHVH.L sp|P49773|HINT1_HUMAN 1 1813.8053 - 81536 11990 3 1813.804043 605.6091 Adenosine 5'-monophosphoramidase HINT1 OS=Homo sapiens OX=9606 GN=HINT1 PE=1 SV=2 5.14 2242.1 - 1.19E+06 - - - -0.7189 - 1.694 0.348 - 61 1 1 0 -0.0013 17 0 0 0 - - - - - 3.7511 0.9998 221125_WJC_METTL3_EV_vs_WT_F06.11991.11991.2 0.000187 17/20 R.K[136.11]EEELQAALAR[166.11].A "sp|Q7Z406|MYH14_HUMAN,sp|P35749|MYH11_HUMAN,sp|P35579|MYH9_HUMAN,tr|A0A0C4DFM8|A0A0C4DFM8_HUMAN" 4 1274.6949 1.65 81537 11991 2 1274.69381 638.3547 Myosin-14 OS=Homo sapiens OX=9606 GN=MYH14 PE=1 SV=2 4.79 2242.2 - 771554 - - - -0.8826 - 3.021 0.272 - 1078.5 1 2 0 -0.0011 11 0 0 0 1.01E+08 6.12E+07 - - - 4.0405 1 221125_WJC_METTL3_EV_vs_WT_F06.11993.11993.2 7.02E-08 26-Nov K.EDLNC[160.03]QEEEDPMNK[136.11].L "sp|O75821|EIF3G_HUMAN,tr|K7EL20|K7EL20_HUMAN,tr|K7ENA8|K7ENA8_HUMAN" 3 1757.6964 1.4 81539 11993 2 1757.69783 879.8555 Eukaryotic translation initiation factor 3 subunit G OS=Homo sapiens OX=9606 GN=EIF3G PE=1 SV=2 3.77 2242.5 - 431141 - - - 0.8249 - 2.373 0.735 - 188.5 1 2 0 0.0014 14 0 0 0 9.09E+06 6.48E+06 - - - 6.6378 0.9992 221125_WJC_METTL3_EV_vs_WT_F06.11994.11994.2 0.000619 18-Sep K.HQTLEVSLSR[166.11].D "sp|Q8NCF5|NF2IP_HUMAN,tr|H3BSZ7|H3BSZ7_HUMAN" 2 1178.6283 0.89 81540 11994 2 1178.631356 590.3214 NFATC2-interacting protein OS=Homo sapiens OX=9606 GN=NFATC2IP PE=1 SV=1 6.75 2242.6 - 311008 - - - 2.5878 - 1.953 0.409 - 223.9 1 2 0 0.0031 10 0 0 0 3.72E+06 4.20E+06 - - - 3.9293 0.998 221125_WJC_METTL3_EV_vs_WT_F06.11995.11995.2 7.55E-06 24-Nov R.K[136.11]EPC[160.03]VLGVDEAGR[166.11].G "sp|O75792|RNH2A_HUMAN,tr|A0A2R8Y606|A0A2R8Y606_HUMAN,tr|A0A2R8Y658|A0A2R8Y658_HUMAN" 3 1446.7256 3.52 81541 11995 2 1446.718634 724.3701 Ribonuclease H2 subunit A OS=Homo sapiens OX=9606 GN=RNASEH2A PE=1 SV=2 4.68 2242.7 - 297884 - - - -4.804 - 2.26 0.511 - 436.7 1 2 0 -0.0069 13 0 0 0 9.26E+06 2.63E+06 - - - 4.9057 0.9795 221125_WJC_METTL3_EV_vs_WT_F06.11999.11999.2 0.0329 16-Sep R.K[136.11]IELFGR[166.11]PH.N sp|Q86U44|MTA70_HUMAN 1 1113.6414 0 81543 11999 2 1113.641394 557.828 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 8.75 2243.1 - 2.05E+07 - - - 0.0099 - 2.051 0.309 - 320 1 1 0 0 9 0 0 0 8.73E+06 3.03E+09 - - - 3.4014 0.9997 221125_WJC_METTL3_EV_vs_WT_F06.12000.12000.3 0.00064 Dec-40 R.KEEELQAALAR.A "sp|Q7Z406|MYH14_HUMAN,sp|P35749|MYH11_HUMAN,sp|P35579|MYH9_HUMAN,tr|A0A0C4DFM8|A0A0C4DFM8_HUMAN" 4 1256.6725 1.1 81544 12000 3 1256.672177 419.8981 Myosin-14 OS=Homo sapiens OX=9606 GN=MYH14 PE=1 SV=2 4.79 2243.2 - 6.23E+06 - - - -0.2292 - 2.345 0.286 - 272.6 1 2 0 -0.0003 11 0 0 0 1.79E+08 1.62E+08 - - - 4.1497 1 221125_WJC_METTL3_EV_vs_WT_F06.12001.12001.3 5.17E-07 13/52 R.KLDPGSEETQTLVR.E sp|P26641|EF1G_HUMAN 1 1571.8155 1.03 81545 12001 3 1571.815933 524.9458 Elongation factor 1-gamma OS=Homo sapiens OX=9606 GN=EEF1G PE=1 SV=3 4.68 2243.2 - 5.31E+06 - - - 0.2748 - 3.017 0.505 - 329.7 1 2 0 0.0004 14 0 0 0 5.02E+08 4.86E+08 - - - 7.1047 1 221125_WJC_METTL3_EV_vs_WT_F06.12002.12002.2 1.14E-06 15/26 R.K[136.11]LDPGSEETQTLVR[166.11].E sp|P26641|EF1G_HUMAN 1 1589.838 0.97 81546 12002 2 1589.838253 795.9263 Elongation factor 1-gamma OS=Homo sapiens OX=9606 GN=EEF1G PE=1 SV=3 4.68 2243.4 - 772664 - - - 0.1774 - 2.904 0.551 - 638.9 1 2 0 0.0003 14 0 0 0 7.10E+07 7.35E+07 - - - 5.7859 0.9949 221125_WJC_METTL3_EV_vs_WT_F06.12003.12003.3 0.101 Nov-44 R.GNNVLYISTQKR.R sp|P62312|LSM6_HUMAN 1 1391.7521 0.13 81547 12003 3 1391.75639 464.9246 U6 snRNA-associated Sm-like protein LSm6 OS=Homo sapiens OX=9606 GN=LSM6 PE=1 SV=1 9.99 2243.5 - 736610 - - - 3.0731 - 1.866 0.258 - 164.9 1 2 0 0.0043 12 0 0 0 1.03E+07 8.03E+07 - - - 3.1443 1 221125_WJC_METTL3_EV_vs_WT_F06.12005.12005.2 2.83E-07 14/26 R.KLDPGSEETQTLVR.E sp|P26641|EF1G_HUMAN 1 1571.8155 0.97 81549 12005 2 1571.817337 786.915 Elongation factor 1-gamma OS=Homo sapiens OX=9606 GN=EEF1G PE=1 SV=3 4.68 2243.8 - 666546 - - - 1.1681 - 2.687 0.598 - 503.3 1 2 0 0.0018 14 0 0 0 7.12E+07 7.35E+07 - - - 5.9377 0.8604 221125_WJC_METTL3_EV_vs_WT_F06.12011.12011.2 0.189 14-Jun K.IELFGR[166.11]PH.N sp|Q86U44|MTA70_HUMAN 1 977.5322 0.02 81553 12011 2 977.531115 489.7734 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 6.75 2244.4 - 5.69E+06 - - - -1.1304 - 1.437 0.218 - 120.3 1 1 0 -0.0011 8 0 0 0 5.66E+06 3.49E+08 - - - 1.7443 0.9994 221125_WJC_METTL3_EV_vs_WT_F06.12012.12012.4 0.0156 13/84 R.IFHTVTTTDDPVIR[166.11]K[136.11].L "sp|O15371|EIF3D_HUMAN,tr|B0QYA5|B0QYA5_HUMAN,tr|B0QYA4|B0QYA4_HUMAN" 3 1759.9588 0.9 81554 12012 4 1759.958025 440.997 Eukaryotic translation initiation factor 3 subunit D OS=Homo sapiens OX=9606 GN=EIF3D PE=1 SV=1 6.75 2244.4 - 4.17E+06 - - - -0.4148 - 1.858 0.326 - 89.6 1 2 0 -0.0007 15 0 0 0 4.16E+07 4.63E+07 - - - 2.285 0.9988 221125_WJC_METTL3_EV_vs_WT_F06.12019.12019.2 0.0194 18-Oct R.NQDNLQGWNK[136.11].T "sp|P30085|KCY_HUMAN,tr|A0A494BXC7|A0A494BXC7_HUMAN,tr|Q5T0D2|Q5T0D2_HUMAN" 3 1223.5774 1.58 81561 12019 2 1223.576854 612.796 UMP-CMP kinase OS=Homo sapiens OX=9606 GN=CMPK1 PE=1 SV=3 5.84 2245.3 - 216038 - - - -0.4863 - 1.557 0.262 - 131.7 1 2 0 -0.0006 10 0 0 0 5.41E+06 3.42E+06 - - - 2.2118 0.9961 221125_WJC_METTL3_EV_vs_WT_F06.12024.12024.3 9.58E-06 Dec-48 K.LHGTAQQLLQDSK.T "sp|Q16513|PKN2_HUMAN,tr|B1AL79|B1AL79_HUMAN" 2 1437.7576 1.28 81565 12024 3 1437.765366 480.2598 Serine\threonine-protein kinase N2 OS=Homo sapiens OX=9606 GN=PKN2 PE=1 SV=1 6.74 2245.7 - 1.16E+06 - - - 5.407 - 2.59 0.318 - 218.7 1 2 0 0.0078 13 0 0 0 1.94E+07 1.52E+07 - - - 4.6635 0.9981 221125_WJC_METTL3_EV_vs_WT_F06.12030.12030.3 0.0163 Sep-44 R.QSVEADINGLRR.V "sp|P13645|K1C10_HUMAN,sp|Q7Z3Y8|K1C27_HUMAN,sp|P13646|K1C13_HUMAN,tr|A0A1B0GVI3|A0A1B0GVI3_HUMAN,tr|K7EMD9|K7EMD9_HUMAN,tr|K7ERE3|K7ERE3_HUMAN" 6 1356.711 1.01 81569 12030 3 1356.710145 453.2443 "Keratin, type I cytoskeletal 10 OS=Homo sapiens OX=9606 GN=KRT10 PE=1 SV=6" 6.07 2246.4 - 1.20E+06 - - - -0.6125 - 1.859 0.235 - 127.1 1 2 0 -0.0008 12 0 0 0 2.80E+07 2.77E+07 - - - 2.8784 0.9995 221125_WJC_METTL3_EV_vs_WT_F06.12031.12031.3 0.0164 Nov-56 R.IFHTVTTTDDPVIRK.L "sp|O15371|EIF3D_HUMAN,tr|B0QYA5|B0QYA5_HUMAN,tr|B0QYA4|B0QYA4_HUMAN" 3 1741.9363 0.99 81570 12031 3 1741.933802 581.6527 Eukaryotic translation initiation factor 3 subunit D OS=Homo sapiens OX=9606 GN=EIF3D PE=1 SV=1 6.75 2246.5 - 2.21E+06 - - - -1.4254 - 1.87 0.339 - 84.4 1 2 0 -0.0025 15 0 0 0 2.23E+07 2.24E+07 - - - 3.9521 0.9968 221125_WJC_METTL3_EV_vs_WT_F06.12039.12039.3 0.221 13/52 K.GLSSDNK[136.11]PMVNLDK[136.11].L "sp|P82979|SARNP_HUMAN,tr|F8VZQ9|F8VZQ9_HUMAN,tr|H0YHG0|H0YHG0_HUMAN" 3 1532.7839 0.54 81576 12039 3 1532.783243 511.9353 SAP domain-containing ribonucleoprotein OS=Homo sapiens OX=9606 GN=SARNP PE=1 SV=3 5.96 2247.4 - 1.52E+06 - - - -0.4567 - 1.603 0.244 - 81.2 1 2 0 -0.0007 14 0 0 0 2.58E+07 4.74E+07 - - - 2.5142 0.8791 221125_WJC_METTL3_EV_vs_WT_F06.12040.12040.2 0.0565 16-Aug R.KIELFGR[166.11]PH.N sp|Q86U44|MTA70_HUMAN 1 1105.6272 - 81577 12040 2 1105.628706 553.8209 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 8.75 2247.5 - 3.83E+06 - - - 1.3775 - 1.558 0.236 - 257.1 1 1 0 0.0015 9 0 0 0 - - - - - 2.0664 0.9998 221125_WJC_METTL3_EV_vs_WT_F06.12042.12042.2 6.25E-07 30-Oct K.APVPGTPDSLSSGSSR[166.11].D "sp|Q9UJZ1|STML2_HUMAN,tr|A0A087WYB4|A0A087WYB4_HUMAN" 2 1523.7455 1.47 81579 12042 2 1523.744753 762.88 "Stomatin-like protein 2, mitochondrial OS=Homo sapiens OX=9606 GN=STOML2 PE=1 SV=1" 5.88 2247.6 - 811648 - - - -0.5034 - 1.996 0.47 - 229.5 1 2 0 -0.0008 16 0 0 0 5.93E+08 4.04E+08 - - - 4.2114 0.9999 221125_WJC_METTL3_EV_vs_WT_F06.12044.12044.2 1.80E-05 22-Oct R.SSTETC[160.03]YSAIPK[136.11].A "sp|O75369|FLNB_HUMAN,tr|E7EN95|E7EN95_HUMAN,tr|A0A804HK76|A0A804HK76_HUMAN" 3 1350.6217 1.03 81581 12044 2 1350.622175 676.3181 Filamin-B OS=Homo sapiens OX=9606 GN=FLNB PE=1 SV=2 5.72 2247.9 - 460507 - - - 0.365 - 2.124 0.516 - 246.3 1 2 0 0.0005 12 0 0 0 6.61E+06 6.40E+06 - - - 4.8341 0.9999 221125_WJC_METTL3_EV_vs_WT_F06.12051.12051.2 7.93E-08 24-Dec R.TAEDDETPVDLNK[136.11].H sp|O00443|P3C2A_HUMAN 1 1453.6664 1.41 81586 12051 2 1453.665411 727.8405 Phosphatidylinositol 4-phosphate 3-kinase C2 domain-containing subunit alpha OS=Homo sapiens OX=9606 GN=PIK3C2A PE=1 SV=2 3.77 2248.6 - 2.43E+06 - - - -0.6687 - 2.552 0.53 - 382.7 1 2 0 -0.001 13 0 0 0 7.00E+07 4.98E+07 - - - 5.3598 1 221125_WJC_METTL3_EV_vs_WT_F06.12054.12054.3 2.63E-07 16/52 K.GLSSDNKPMVNLDK.L "sp|P82979|SARNP_HUMAN,tr|F8VZQ9|F8VZQ9_HUMAN,tr|H0YHG0|H0YHG0_HUMAN" 3 1516.7555 0.55 81589 12054 3 1516.757021 506.5925 SAP domain-containing ribonucleoprotein OS=Homo sapiens OX=9606 GN=SARNP PE=1 SV=3 5.96 2248.9 - 1.20E+06 - - - 0.9744 - 2.564 0.518 - 219.5 1 2 0 0.0015 14 0 0 0 2.58E+07 4.72E+07 - - - 6.817 0.9994 221125_WJC_METTL3_EV_vs_WT_F06.12055.12055.3 0.00504 Nov-40 K.LQQLVENIDKK.A "sp|Q9NSC2|SALL1_HUMAN,sp|Q9BXA9|SALL3_HUMAN,tr|A0A087WXW6|A0A087WXW6_HUMAN,tr|A0A140TA74|A0A140TA74_HUMAN,tr|A0A140TA70|A0A140TA70_HUMAN,tr|H3BSM9|H3BSM9_HUMAN,tr|A9JR48|A9JR48_HUMAN" 7 1326.7507 1.88 81590 12055 3 1326.750118 443.2575 Sal-like protein 1 OS=Homo sapiens OX=9606 GN=SALL1 PE=1 SV=2 6.07 2249 - 1.19E+06 - - - -0.4507 - 2.171 0.259 - 261.3 1 2 0 -0.0006 11 0 0 0 2.68E+07 1.43E+07 - - - 3.6296 0.9999 221125_WJC_METTL3_EV_vs_WT_F06.12057.12057.2 6.01E-06 13/24 K.NSSSSGTSLLTPK[136.11].S sp|Q9NXV6|CARF_HUMAN 1 1285.6605 0.9 81592 12057 2 1285.661675 643.8375 CDKN2A-interacting protein OS=Homo sapiens OX=9606 GN=CDKN2AIP PE=1 SV=3 8.75 2249.2 - 697189 - - - 0.9061 - 2.718 0.472 - 643.7 1 2 0 0.0012 13 0 0 0 1.54E+07 1.72E+07 - - - 5.0931 1 221125_WJC_METTL3_EV_vs_WT_F06.12058.12058.2 0.00011 16/26 K.IQALQQQADEAEDR.A "sp|P67936|TPM4_HUMAN,tr|A0A590UJB9|A0A590UJB9_HUMAN,tr|A0A2R8Y5V9|A0A2R8Y5V9_HUMAN,tr|A0A2R8YGX3|A0A2R8YGX3_HUMAN,tr|A0A590UK79|A0A590UK79_HUMAN" 5 1613.7645 49.81 81593 12058 2 1613.765867 807.8895 Tropomyosin alpha-4 chain OS=Homo sapiens OX=9606 GN=TPM4 PE=1 SV=3 3.92 2249.4 - 614216 - - - 0.8297 - 3.251 0.521 - 998.7 1 2 0 0.0013 14 0 0 0 7.42E+06 1.49E+05 - - - 5.8472 0.998 221125_WJC_METTL3_EV_vs_WT_F06.12059.12059.2 0.0039 22-Aug R.SSTETC[160.03]YSAIPK.A "sp|O75369|FLNB_HUMAN,tr|E7EN95|E7EN95_HUMAN,tr|A0A804HK76|A0A804HK76_HUMAN" 3 1342.6075 1.03 81594 12059 2 1342.611722 672.311 Filamin-B OS=Homo sapiens OX=9606 GN=FLNB PE=1 SV=2 5.72 2249.5 - 601407 - - - 3.158 - 1.551 0.416 - 140.8 1 2 0 0.0042 12 0 0 0 6.61E+06 6.40E+06 - - - 3.2671 0.9992 221125_WJC_METTL3_EV_vs_WT_F06.12062.12062.2 0.0241 20-Dec R.KEEELQAALAR.A "sp|Q7Z406|MYH14_HUMAN,sp|P35749|MYH11_HUMAN,sp|P35579|MYH9_HUMAN,tr|A0A0C4DFM8|A0A0C4DFM8_HUMAN" 4 1256.6725 1.68 81596 12062 2 1256.669775 629.3435 Myosin-14 OS=Homo sapiens OX=9606 GN=MYH14 PE=1 SV=2 4.79 2249.9 - 4.18E+06 - - - -2.1406 - 1.942 0.353 - 233.6 1 2 0 -0.0027 11 0 0 0 1.03E+08 6.12E+07 - - - 3.4429 1 221125_WJC_METTL3_EV_vs_WT_F06.12064.12064.2 1.83E-09 16/30 K.APVPGTPDSLSSGSSR.D "sp|Q9UJZ1|STML2_HUMAN,tr|A0A087WYB4|A0A087WYB4_HUMAN" 2 1513.7372 1.4 81597 12064 2 1513.738453 757.8759 "Stomatin-like protein 2, mitochondrial OS=Homo sapiens OX=9606 GN=STOML2 PE=1 SV=1" 5.88 2250.1 - 1.79E+06 - - - 0.7947 - 2.534 0.674 - 665.8 1 2 0 0.0012 16 0 0 0 5.66E+08 4.03E+08 - - - 6.3047 0.9999 221125_WJC_METTL3_EV_vs_WT_F06.12065.12065.3 0.000362 15/40 K.QDLPSLDEK[136.11]PR[166.11].L sp|Q92598|HS105_HUMAN 1 1314.6898 1.92 81598 12065 3 1314.689694 439.2372 Heat shock protein 105 kDa OS=Homo sapiens OX=9606 GN=HSPH1 PE=1 SV=1 4.56 2250.1 - 2.17E+06 - - - -0.1187 - 2.824 0.394 - 546.9 1 2 0 -0.0002 11 0 0 0 9.08E+08 4.73E+08 - - - 5.8819 0.9995 221125_WJC_METTL3_EV_vs_WT_F06.12066.12066.3 0.000974 14/48 R.K[136.11]NPLPPSVGVVDK[136.11].K sp|Q8NC51|PAIRB_HUMAN 1 1364.7999 0.67 81599 12066 3 1364.801014 455.9406 Plasminogen activator inhibitor 1 RNA-binding protein OS=Homo sapiens OX=9606 GN=SERBP1 PE=1 SV=2 8.59 2250.2 - 975656 - - - 0.8521 - 1.92 0.315 - 169.1 1 2 0 0.0012 13 0 0 0 7.11E+07 1.06E+08 - - - 3.8203 0.9981 221125_WJC_METTL3_EV_vs_WT_F06.12067.12067.3 0.0503 Nov-40 K.LQQLVENIDK[136.11]K[136.11].A "sp|Q9NSC2|SALL1_HUMAN,sp|Q9BXA9|SALL3_HUMAN,tr|A0A087WXW6|A0A087WXW6_HUMAN,tr|A0A140TA74|A0A140TA74_HUMAN,tr|A0A140TA70|A0A140TA70_HUMAN,tr|H3BSM9|H3BSM9_HUMAN,tr|A9JR48|A9JR48_HUMAN" 7 1342.7791 1.92 81600 12067 3 1342.78344 448.6003 Sal-like protein 1 OS=Homo sapiens OX=9606 GN=SALL1 PE=1 SV=2 6.07 2250.3 - 917652 - - - 3.2202 - 2.158 0.29 - 211.1 1 2 0 0.0043 11 0 0 0 2.71E+07 1.41E+07 - - - 3.9571 0.9425 221125_WJC_METTL3_EV_vs_WT_F06.12068.12068.2 6.73E-07 13/32 R.GSGGLGGAC[160.03]GGAGFGSR.S "sp|P48668|K2C6C_HUMAN,sp|P04259|K2C6B_HUMAN,sp|P02538|K2C6A_HUMAN" 3 1423.6263 999 81601 12068 2 1424.622901 712.8204 "Keratin, type II cytoskeletal 6C OS=Homo sapiens OX=9606 GN=KRT6C PE=1 SV=3" 8.25 2250.4 - 574538 - - - 700.0721 - 2.568 0.581 - 386.1 1 2 0 0.9966 17 0 0 0 5.61E+06 0.00E+00 - - - 5.338 1 221125_WJC_METTL3_EV_vs_WT_F06.12069.12069.2 4.50E-08 28-Dec R.YTPSQQGVAFNSGAK.Q "sp|Q13573|SNW1_HUMAN,tr|G3V4X8|G3V4X8_HUMAN,tr|G3V3A4|G3V3A4_HUMAN" 3 1553.7474 3.13 81602 12069 2 1553.749294 777.881 SNW domain-containing protein 1 OS=Homo sapiens OX=9606 GN=SNW1 PE=1 SV=1 8.59 2250.6 - 368901 - - - 1.2055 - 2.57 0.599 - 453.9 1 2 0 0.0019 15 0 0 0 2.90E+08 9.27E+07 - - - 5.7853 0.9996 221125_WJC_METTL3_EV_vs_WT_F06.12070.12070.2 0.0183 20-Dec K.QDLPSLDEK[136.11]PR[166.11].L sp|Q92598|HS105_HUMAN 1 1314.6898 0.01 81603 12070 2 1314.690546 658.3522 Heat shock protein 105 kDa OS=Homo sapiens OX=9606 GN=HSPH1 PE=1 SV=1 4.56 2250.7 - 230150 - - - 0.5294 - 2.312 0.297 - 642.2 1 2 0 0.0007 11 0 0 0 2.93E+05 3.17E+07 - - - 3.5017 1 221125_WJC_METTL3_EV_vs_WT_F06.12075.12075.2 5.98E-11 17/24 R.TAEDDETPVDLNK.H sp|O00443|P3C2A_HUMAN 1 1445.6522 1.41 81606 12075 2 1445.652043 723.8334 Phosphatidylinositol 4-phosphate 3-kinase C2 domain-containing subunit alpha OS=Homo sapiens OX=9606 GN=PIK3C2A PE=1 SV=2 3.77 2251.2 - 4.92E+06 - - - -0.0968 - 3.299 0.737 - 961.7 1 2 0 -0.0001 13 0 0 0 7.00E+07 4.98E+07 - - - 7.5479 1 221125_WJC_METTL3_EV_vs_WT_F06.12076.12076.2 1.38E-09 13/28 R.YTPSQQGVAFNSGAK[136.11].Q "sp|Q13573|SNW1_HUMAN,tr|G3V4X8|G3V4X8_HUMAN,tr|G3V3A4|G3V3A4_HUMAN" 3 1561.7616 3.13 81607 12076 2 1561.760586 781.8881 SNW domain-containing protein 1 OS=Homo sapiens OX=9606 GN=SNW1 PE=1 SV=1 8.59 2251.4 - 973209 - - - -0.6627 - 2.614 0.643 - 641.1 1 2 0 -0.001 15 0 0 0 2.90E+08 9.27E+07 - - - 6.1522 0.9994 221125_WJC_METTL3_EV_vs_WT_F06.12077.12077.3 0.00014 Oct-44 K.QLEDLSYC[160.03]REER.K "sp|Q99567|NUP88_HUMAN,tr|I3L4K7|I3L4K7_HUMAN,tr|J3KMX1|J3KMX1_HUMAN" 3 1596.7202 1.86 81608 12077 3 1596.721302 533.2473 Nuclear pore complex protein Nup88 OS=Homo sapiens OX=9606 GN=NUP88 PE=1 SV=2 4.41 2251.4 - 1.37E+06 - - - 0.6776 - 1.912 0.412 - 210.5 1 2 1 0.0011 12 0 0 0 1.15E+07 6.18E+06 - - - 4.9297 1 221125_WJC_METTL3_EV_vs_WT_F06.12078.12078.3 8.75E-07 18/56 R.RPISADSAIMNPASK.V "sp|Q00610|CLH1_HUMAN,tr|J3KSQ2|J3KSQ2_HUMAN,tr|J3KS13|J3KS13_HUMAN,tr|J3QL20|J3QL20_HUMAN,tr|A0A087WVQ6|A0A087WVQ6_HUMAN" 5 1556.7981 0.68 81609 12078 3 1556.797144 519.94 Clathrin heavy chain 1 OS=Homo sapiens OX=9606 GN=CLTC PE=1 SV=5 8.75 2251.5 - 842154 - - - -0.5987 - 3.05 0.5 - 591.9 1 2 0 -0.0009 15 0 0 0 1.29E+08 1.91E+08 - - - 7.0241 0.9999 221125_WJC_METTL3_EV_vs_WT_F06.12079.12079.2 2.44E-08 22-Dec K.GSFSDTGLGDGK[136.11].M "sp|Q9Y2W1|TR150_HUMAN,tr|A0A3B3ITZ9|A0A3B3ITZ9_HUMAN" 2 1147.5237 2.86 81610 12079 2 1147.522425 574.7691 Thyroid hormone receptor-associated protein 3 OS=Homo sapiens OX=9606 GN=THRAP3 PE=1 SV=2 4.21 2251.7 - 791585 - - - -1.0954 - 2.241 0.545 - 290.1 1 2 0 -0.0013 12 0 0 0 2.83E+08 9.90E+07 - - - 5.1891 0.9968 221125_WJC_METTL3_EV_vs_WT_F06.12081.12081.3 0.118 13/44 K.QLEDLSYC[160.03]R[166.11]EER[166.11].K "sp|Q99567|NUP88_HUMAN,tr|I3L4K7|I3L4K7_HUMAN,tr|J3KMX1|J3KMX1_HUMAN" 3 1616.7368 1.86 81612 12081 3 1616.733269 539.9195 Nuclear pore complex protein Nup88 OS=Homo sapiens OX=9606 GN=NUP88 PE=1 SV=2 4.41 2251.9 - 624498 - - - -2.1593 - 2.371 0.285 - 333.8 1 2 1 -0.0035 12 0 0 0 1.15E+07 6.18E+06 - - - 4.1095 1 221125_WJC_METTL3_EV_vs_WT_F06.12084.12084.2 2.70E-06 22-Dec K.GSFSDTGLGDGK.M "sp|Q9Y2W1|TR150_HUMAN,tr|A0A3B3ITZ9|A0A3B3ITZ9_HUMAN" 2 1139.5095 2.86 81613 12084 2 1139.509369 570.762 Thyroid hormone receptor-associated protein 3 OS=Homo sapiens OX=9606 GN=THRAP3 PE=1 SV=2 4.21 2252.3 - 3.78E+06 - - - -0.0992 - 2.338 0.621 - 309.1 1 2 0 -0.0001 12 0 0 0 2.83E+08 9.90E+07 - - - 5.8623 0.9999 221125_WJC_METTL3_EV_vs_WT_F06.12088.12088.2 2.01E-07 24-Sep K.GQNPSATFGDVSK.L sp|Q96NM4|TOX2_HUMAN 1 1306.6153 2.46 81617 12088 2 1306.613225 654.3149 TOX high mobility group box family member 2 OS=Homo sapiens OX=9606 GN=TOX2 PE=1 SV=2 5.84 2252.7 - 707164 - - - -1.6217 - 2.141 0.613 - 237.7 1 2 0 -0.0021 13 0 0 0 1.25E+07 5.10E+06 - - - 5.5218 0.9982 221125_WJC_METTL3_EV_vs_WT_F06.12089.12089.2 2.58E-06 22-Dec K.IIYIVHDEVK[136.11]DK[136.11].A "sp|P25788|PSA3_HUMAN,tr|G3V4X5|G3V4X5_HUMAN" 2 1486.8366 53.11 81618 12089 2 1486.834633 744.4256 Proteasome subunit alpha type-3 OS=Homo sapiens OX=9606 GN=PSMA3 PE=1 SV=2 5.38 2252.8 - 309578 - - - -1.3431 - 2.182 0.527 - 375.9 1 2 1 -0.002 12 0 0 0 2.03E+08 3.83E+06 - - - 4.9857 0.9999 221125_WJC_METTL3_EV_vs_WT_F06.12091.12091.2 9.65E-06 24-Dec K.GQNPSATFGDVSK[136.11].L sp|Q96NM4|TOX2_HUMAN 1 1314.6295 2.46 81620 12091 2 1314.628347 658.322 TOX high mobility group box family member 2 OS=Homo sapiens OX=9606 GN=TOX2 PE=1 SV=2 5.84 2253.1 - 267994 - - - -0.9105 - 1.983 0.544 - 469.1 1 2 0 -0.0012 13 0 0 0 1.25E+07 5.10E+06 - - - 4.8157 0.9952 221125_WJC_METTL3_EV_vs_WT_F06.12094.12094.3 0.00875 14/44 K.IIYIVHDEVK[136.11]DK[136.11].A "sp|P25788|PSA3_HUMAN,tr|G3V4X5|G3V4X5_HUMAN" 2 1486.8366 1.58 81621 12094 3 1486.843357 496.6195 Proteasome subunit alpha type-3 OS=Homo sapiens OX=9606 GN=PSMA3 PE=1 SV=2 5.38 2253.5 - 3.23E+06 - - - 4.5244 - 2.256 0.405 - 308.1 1 2 1 0.0067 12 0 0 0 5.68E+07 3.60E+07 - - - 5.3086 0.9992 221125_WJC_METTL3_EV_vs_WT_F06.12096.12096.3 0.00148 Nov-48 R.ALDKLDGTEINGR.N "sp|Q13247|SRSF6_HUMAN,tr|A0A590UK80|A0A590UK80_HUMAN,tr|A0A590UJK4|A0A590UJK4_HUMAN,tr|A0A590UJP7|A0A590UJP7_HUMAN,tr|A0A590UK01|A0A590UK01_HUMAN" 5 1400.726 1.55 81623 12096 3 1400.725318 467.9159 Serine\arginine-rich splicing factor 6 OS=Homo sapiens OX=9606 GN=SRSF6 PE=1 SV=2 4.56 2253.6 - 2.05E+06 - - - -0.4562 - 2.248 0.352 - 109.3 1 2 1 -0.0006 13 0 0 0 7.03E+07 4.54E+07 - - - 4.6605 1 221125_WJC_METTL3_EV_vs_WT_F06.12097.12097.3 2.12E-05 14/48 R.KNPLPPSVGVVDK.K sp|Q8NC51|PAIRB_HUMAN 1 1348.7715 0.66 81624 12097 3 1348.770068 450.5978 Plasminogen activator inhibitor 1 RNA-binding protein OS=Homo sapiens OX=9606 GN=SERBP1 PE=1 SV=2 8.59 2253.7 - 1.18E+06 - - - -1.0254 - 2.579 0.477 - 253.3 1 2 0 -0.0014 13 0 0 0 6.47E+07 9.85E+07 - - - 6.4264 0.9998 221125_WJC_METTL3_EV_vs_WT_F06.12098.12098.2 0.00492 20-Nov K.NSEPEEVIPSR[166.11].L "sp|P54577|SYYC_HUMAN,tr|A0A6Q8PFX2|A0A6Q8PFX2_HUMAN" 2 1265.6127 0.96 81625 12098 2 1265.612818 633.8136 "Tyrosine--tRNA ligase, cytoplasmic OS=Homo sapiens OX=9606 GN=YARS1 PE=1 SV=4" 4.25 2253.8 - 1.13E+06 - - - 0.0814 - 2.147 0.453 - 507.5 1 2 0 0.0001 11 0 0 0 3.15E+07 3.28E+07 - - - 4.4538 1 221125_WJC_METTL3_EV_vs_WT_F06.12101.12101.2 9.72E-08 13/24 R.SEDQNC[160.03]VPPLQER[166.11].K sp|Q5JSZ5|PRC2B_HUMAN 1 1580.7128 2.77 81628 12101 2 1580.713324 791.3637 Protein PRRC2B OS=Homo sapiens OX=9606 GN=PRRC2B PE=1 SV=2 4.14 2254.2 - 446267 - - - 0.3062 - 2.752 0.578 - 355.1 1 2 0 0.0005 13 0 0 0 2.48E+07 8.94E+06 - - - 5.9081 0.9994 221125_WJC_METTL3_EV_vs_WT_F06.12109.12109.3 4.93E-06 Dec-48 R.ALDK[136.11]LDGTEINGR[166.11].N "sp|Q13247|SRSF6_HUMAN,tr|A0A590UK80|A0A590UK80_HUMAN,tr|A0A590UJK4|A0A590UJK4_HUMAN,tr|A0A590UJP7|A0A590UJP7_HUMAN,tr|A0A590UK01|A0A590UK01_HUMAN" 5 1418.7484 1.41 81634 12109 3 1418.75079 473.9234 Serine\arginine-rich splicing factor 6 OS=Homo sapiens OX=9606 GN=SRSF6 PE=1 SV=2 4.56 2254.9 - 2.73E+06 - - - 1.6656 - 1.969 0.456 - 172 1 2 1 0.0024 13 0 0 0 6.43E+07 4.56E+07 - - - 5.4603 0.9995 221125_WJC_METTL3_EV_vs_WT_F06.12110.12110.3 0.017 Dec-44 R.TNAENEFVTIKK.D sp|P04264|K2C1_HUMAN 1 1392.7249 999 81635 12110 3 1392.725752 465.2489 "Keratin, type II cytoskeletal 1 OS=Homo sapiens OX=9606 GN=KRT1 PE=1 SV=6" 5.81 2254.9 - 1.59E+06 - - - 0.6153 - 1.903 0.318 - 220.8 1 2 0 0.0009 12 0 0 0 1.87E+07 0.00E+00 - - - 3.8686 0.9931 221125_WJC_METTL3_EV_vs_WT_F06.12111.12111.3 0.111 Nov-44 K.GEIPSPQLTRPK.K tr|H7C0V5|H7C0V5_HUMAN 1 1321.7354 0.83 81636 12111 3 1321.738676 441.5857 ANKHD1-EIF4EBP3 readthrough (Fragment) OS=Homo sapiens OX=9606 GN=ANKHD1-EIF4EBP3 PE=4 SV=1 8.75 2255 - 1.31E+06 - - - 2.4786 - 2.065 0.189 - 225.1 1 2 0 0.0033 12 0 0 0 2.56E+07 3.09E+07 - - - 2.6562 0.9999 221125_WJC_METTL3_EV_vs_WT_F06.12113.12113.2 2.61E-05 26-Oct R.SSFYPDGGDQETAK.T "sp|Q9NYF8|BCLF1_HUMAN,tr|H0YF00|H0YF00_HUMAN,tr|E9PKI6|E9PKI6_HUMAN,tr|A0A1W2PQ43|A0A1W2PQ43_HUMAN,tr|E9PK91|E9PK91_HUMAN,tr|E9PJA7|E9PJA7_HUMAN,tr|E9PK09|E9PK09_HUMAN,tr|E9PQN2|E9PQN2_HUMAN" 8 1500.6369 1.97 81638 12113 2 1500.636667 751.3257 Bcl-2-associated transcription factor 1 OS=Homo sapiens OX=9606 GN=BCLAF1 PE=1 SV=2 4.03 2255.3 - 792205 - - - -0.1339 - 1.769 0.599 - 186 1 2 0 -0.0002 14 0 0 0 1.86E+07 9.45E+06 - - - 4.8966 0.9999 221125_WJC_METTL3_EV_vs_WT_F06.12116.12116.2 5.09E-06 26-Oct R.SSFYPDGGDQETAK[136.11].T "sp|Q9NYF8|BCLF1_HUMAN,tr|H0YF00|H0YF00_HUMAN,tr|E9PKI6|E9PKI6_HUMAN,tr|A0A1W2PQ43|A0A1W2PQ43_HUMAN,tr|E9PK91|E9PK91_HUMAN,tr|E9PJA7|E9PJA7_HUMAN,tr|E9PK09|E9PK09_HUMAN,tr|E9PQN2|E9PQN2_HUMAN" 8 1508.6511 2.04 81641 12116 2 1508.65125 755.3328 Bcl-2-associated transcription factor 1 OS=Homo sapiens OX=9606 GN=BCLAF1 PE=1 SV=2 4.03 2255.7 - 499244 - - - 0.1206 - 1.712 0.559 - 185.9 1 2 0 0.0002 14 0 0 0 8.10E+06 3.97E+06 - - - 4.519 0.9998 221125_WJC_METTL3_EV_vs_WT_F06.12120.12120.2 1.61E-05 24-Oct R.TTTENMAPIPGSK[136.11].R sp|Q5VT06|CE350_HUMAN 1 1353.669 2.86 81645 12120 2 1353.667292 677.8418 Centrosome-associated protein 350 OS=Homo sapiens OX=9606 GN=CEP350 PE=1 SV=1 5.66 2256.2 - 205759 - - - -1.2366 - 2.079 0.472 - 208.4 1 2 0 -0.0017 13 0 0 0 8.05E+06 2.81E+06 - - - 4.4051 1 221125_WJC_METTL3_EV_vs_WT_F06.12121.12121.3 1.05E-08 20/52 K.VEAQHILASAPTDR[166.11].N "sp|Q53H96|P5CR3_HUMAN,tr|A0A0A0MQS1|A0A0A0MQS1_HUMAN" 2 1516.7873 0.9 81646 12121 3 1516.788652 506.6031 Pyrroline-5-carboxylate reductase 3 OS=Homo sapiens OX=9606 GN=PYCR3 PE=1 SV=3 5.32 2256.3 - 1.28E+06 - - - 0.8742 - 3.353 0.382 - 790.6 1 2 0 0.0013 14 0 0 0 2.87E+07 3.20E+07 - - - 6.0138 0.9999 221125_WJC_METTL3_EV_vs_WT_F06.12123.12123.3 7.59E-05 Dec-44 K.LHGVNINVEASK[136.11].N "sp|Q9BWF3|RBM4_HUMAN,sp|Q9BQ04|RBM4B_HUMAN,tr|E9PM61|E9PM61_HUMAN,tr|D6R9K7|D6R9K7_HUMAN,tr|J3QRR5|J3QRR5_HUMAN,tr|E9PB51|E9PB51_HUMAN,tr|U3KQD5|U3KQD5_HUMAN,tr|E9PLB0|E9PLB0_HUMAN" 8 1287.7026 0.99 81647 12123 3 1287.701986 430.2415 RNA-binding protein 4 OS=Homo sapiens OX=9606 GN=RBM4 PE=1 SV=1 6.75 2256.5 - 2.82E+06 - - - -0.5156 - 2.52 0.39 - 261.3 1 2 0 -0.0007 12 0 0 0 1.51E+08 1.52E+08 - - - 5.4498 1 221125_WJC_METTL3_EV_vs_WT_F06.12126.12126.3 5.48E-06 16/52 K.VEAQHILASAPTDR[166.11].N "sp|Q53H96|P5CR3_HUMAN,tr|A0A0A0MQS1|A0A0A0MQS1_HUMAN" 2 1516.7873 0.9 81650 12126 3 1516.788465 506.6031 Pyrroline-5-carboxylate reductase 3 OS=Homo sapiens OX=9606 GN=PYCR3 PE=1 SV=3 5.32 2256.7 - 2.47E+06 - - - 0.7509 - 3.363 0.424 - 557.7 1 2 0 0.0011 14 0 0 0 2.87E+07 3.20E+07 - - - 6.49 0.9997 221125_WJC_METTL3_EV_vs_WT_F06.12128.12128.2 0.00145 20-Nov K.NSEPEEVIPSR.L "sp|P54577|SYYC_HUMAN,tr|A0A6Q8PFX2|A0A6Q8PFX2_HUMAN" 2 1255.6044 0.92 81652 12128 2 1255.605147 628.8095 "Tyrosine--tRNA ligase, cytoplasmic OS=Homo sapiens OX=9606 GN=YARS1 PE=1 SV=4" 4.25 2256.9 - 1.16E+06 - - - 0.5591 - 1.848 0.387 - 247.1 1 2 0 0.0007 11 0 0 0 3.20E+07 3.48E+07 - - - 3.5605 1 221125_WJC_METTL3_EV_vs_WT_F06.12129.12129.2 0.0142 14/22 R.TNAENEFVTIKK.D sp|P04264|K2C1_HUMAN 1 1392.7249 999 81653 12129 2 1392.724236 697.3697 "Keratin, type II cytoskeletal 1 OS=Homo sapiens OX=9606 GN=KRT1 PE=1 SV=6" 5.81 2257 - 1.13E+06 - - - -0.4732 - 2.896 0.581 - 675.8 1 2 0 -0.0007 12 0 0 0 8.99E+09 0.00E+00 - - - 6.1299 0.9957 221125_WJC_METTL3_EV_vs_WT_F06.12132.12132.2 4.49E-06 26-Dec K.AQAELVGTADEATR.A sp|P30049|ATPD_HUMAN 1 1430.7001 999 81656 12132 2 1430.708272 716.3573 "ATP synthase subunit delta, mitochondrial OS=Homo sapiens OX=9606 GN=ATP5F1D PE=1 SV=2" 4.14 2257.4 - 485721 - - - 5.686 - 2.053 0.518 - 288.9 1 2 0 0.0081 14 0 0 0 1.84E+07 0.00E+00 - - - 4.6694 0.9997 221125_WJC_METTL3_EV_vs_WT_F06.12136.12136.3 0.00554 Oct-44 K.LHGVNINVEASK.N "sp|Q9BWF3|RBM4_HUMAN,sp|Q9BQ04|RBM4B_HUMAN,tr|E9PM61|E9PM61_HUMAN,tr|D6R9K7|D6R9K7_HUMAN,tr|J3QRR5|J3QRR5_HUMAN,tr|E9PB51|E9PB51_HUMAN,tr|U3KQD5|U3KQD5_HUMAN,tr|E9PLB0|E9PLB0_HUMAN" 8 1279.6885 0.97 81658 12136 3 1279.688442 427.5701 RNA-binding protein 4 OS=Homo sapiens OX=9606 GN=RBM4 PE=1 SV=1 6.75 2257.8 - 4.50E+06 - - - -0.0063 - 1.845 0.358 - 134.9 1 2 0 0 12 0 0 0 1.10E+08 1.13E+08 - - - 4.229 0.9995 221125_WJC_METTL3_EV_vs_WT_F06.12138.12138.3 0.00482 15/56 R.LQQSHPLSATQIQVK[136.11].R "sp|Q13813|SPTN1_HUMAN,tr|A0A0D9SF54|A0A0D9SF54_HUMAN,tr|A0A0D9SGF6|A0A0D9SGF6_HUMAN" 3 1684.9352 1.43 81660 12138 3 1684.928514 562.6523 "Spectrin alpha chain, non-erythrocytic 1 OS=Homo sapiens OX=9606 GN=SPTAN1 PE=1 SV=3" 8.76 2258 - 1.25E+06 - - - -3.9497 - 2.755 0.405 - 248.6 1 2 0 -0.0067 15 0 0 0 9.85E+07 6.88E+07 - - - 5.6979 0.9491 221125_WJC_METTL3_EV_vs_WT_F06.12144.12144.2 0.0136 24-Dec R.ALDK[136.11]LDGTEINGR[166.11].N "sp|Q13247|SRSF6_HUMAN,tr|A0A590UK80|A0A590UK80_HUMAN,tr|A0A590UJK4|A0A590UJK4_HUMAN,tr|A0A590UJP7|A0A590UJP7_HUMAN,tr|A0A590UK01|A0A590UK01_HUMAN" 5 1418.7484 0.66 81666 12144 2 1418.751132 710.3815 Serine\arginine-rich splicing factor 6 OS=Homo sapiens OX=9606 GN=SRSF6 PE=1 SV=2 4.56 2258.7 - 398358 - - - 1.9066 - 1.604 0.199 - 212.7 1 2 1 0.0027 13 0 0 0 8.36E+06 1.26E+07 - - - 1.7227 1 221125_WJC_METTL3_EV_vs_WT_F06.12149.12149.3 1.96E-06 13/48 K.ISADTHQFSVTER.E "sp|Q96RQ1|ERGI2_HUMAN,tr|H0YI50|H0YI50_HUMAN,tr|A0A087WU02|A0A087WU02_HUMAN,tr|H0YI58|H0YI58_HUMAN" 4 1489.7161 2.03 81669 12149 3 1489.714264 497.5793 Endoplasmic reticulum-Golgi intermediate compartment protein 2 OS=Homo sapiens OX=9606 GN=ERGIC2 PE=1 SV=2 5.32 2259.3 - 1.94E+06 - - - -1.2465 - 2.508 0.53 - 209.3 1 2 0 -0.0019 13 0 0 0 2.03E+07 1.00E+07 - - - 6.9415 0.9912 221125_WJC_METTL3_EV_vs_WT_F06.12150.12150.2 3.85E-07 18-Oct A.AENEFVTLKK.D "sp|P48668|K2C6C_HUMAN,sp|P12035|K2C3_HUMAN,sp|P04264|K2C1_HUMAN,sp|P04259|K2C6B_HUMAN,sp|P02538|K2C6A_HUMAN" 5 1177.6343 999 81670 12150 2 1177.63423 589.8244 "Keratin, type II cytoskeletal 6C OS=Homo sapiens OX=9606 GN=KRT6C PE=1 SV=3" 6.19 2259.4 - 1.57E+06 - - - -0.0501 - 2.281 0.428 - 422.8 1 1 0 -0.0001 10 0 0 0 5.85E+08 0.00E+00 - - - 4.5039 1 221125_WJC_METTL3_EV_vs_WT_F06.12152.12152.2 5.68E-07 14/20 T.NAENEFVTIKK.D sp|P04264|K2C1_HUMAN 1 1291.6772 999 81672 12152 2 1291.682809 646.8459 "Keratin, type II cytoskeletal 1 OS=Homo sapiens OX=9606 GN=KRT1 PE=1 SV=6" 6.14 2259.7 - 789346 - - - 4.33 - 2.723 0.554 - 766.4 1 1 0 0.0056 11 0 0 0 3.83E+08 0.00E+00 - - - 5.841 1 221125_WJC_METTL3_EV_vs_WT_F06.12153.12153.2 1.33E-08 13/18 K.C[160.03]DTC[160.03]QQYFSR[166.11].T sp|Q9Y2X9|ZN281_HUMAN 1 1373.5368 1.21 81673 12153 2 1373.536364 687.7757 Zinc finger protein 281 OS=Homo sapiens OX=9606 GN=ZNF281 PE=1 SV=1 5.82 2259.8 - 674719 - - - -0.3101 - 2.626 0.588 - 1248.4 1 2 0 -0.0004 10 0 0 0 6.17E+07 5.10E+07 - - - 6.0787 0.9997 221125_WJC_METTL3_EV_vs_WT_F06.12154.12154.2 3.91E-06 16/28 R.R[166.11]PISADSAIMNPASK[136.11].V "sp|Q00610|CLH1_HUMAN,tr|J3KSQ2|J3KSQ2_HUMAN,tr|J3KS13|J3KS13_HUMAN,tr|J3QL20|J3QL20_HUMAN,tr|A0A087WVQ6|A0A087WVQ6_HUMAN" 5 1574.8205 0.03 81674 12154 2 1574.816366 788.4175 Clathrin heavy chain 1 OS=Homo sapiens OX=9606 GN=CLTC PE=1 SV=5 8.75 2259.9 - 529750 - - - -2.6543 - 2.839 0.555 - 568.7 1 2 0 -0.0042 15 0 0 0 3.32E+05 9.89E+06 - - - 5.7043 0.9995 221125_WJC_METTL3_EV_vs_WT_F06.12160.12160.2 1.13E-05 26-Oct R.SVSEINSDDELSGK[136.11].G "sp|P82094|TMF1_HUMAN,tr|F8WF45|F8WF45_HUMAN,tr|A0A2R8Y7M0|A0A2R8Y7M0_HUMAN" 3 1486.6878 2.3 81678 12160 2 1486.683073 744.3512 TATA element modulatory factor OS=Homo sapiens OX=9606 GN=TMF1 PE=1 SV=2 3.92 2260.6 - 901659 - - - -3.2112 - 2.388 0.574 - 178.7 1 2 0 -0.0048 14 0 0 0 7.30E+07 3.17E+07 - - - 5.4634 1 221125_WJC_METTL3_EV_vs_WT_F06.12161.12161.3 1.59E-05 15/44 K.DGMVSFHDNPEK[136.11].Y "sp|Q9UNS2|CSN3_HUMAN,tr|H7C3P9|H7C3P9_HUMAN,tr|K7ELN6|K7ELN6_HUMAN" 3 1382.6016 0.53 81679 12161 3 1382.601929 461.8745 COP9 signalosome complex subunit 3 OS=Homo sapiens OX=9606 GN=COPS3 PE=1 SV=3 4.54 2260.7 - 742746 - - - 0.2271 - 2.348 0.538 - 245.9 1 2 0 0.0003 12 0 0 0 6.69E+06 1.27E+07 - - - 6.904 1 221125_WJC_METTL3_EV_vs_WT_F06.12162.12162.2 2.32E-10 16/26 R.SVSEINSDDELSGK.G "sp|P82094|TMF1_HUMAN,tr|F8WF45|F8WF45_HUMAN,tr|A0A2R8Y7M0|A0A2R8Y7M0_HUMAN" 3 1478.6736 2.3 81680 12162 2 1478.672772 740.3441 TATA element modulatory factor OS=Homo sapiens OX=9606 GN=TMF1 PE=1 SV=2 3.92 2260.8 - 649600 - - - -0.5917 - 3.051 0.655 - 727.6 1 2 0 -0.0009 14 0 0 0 7.30E+07 3.17E+07 - - - 6.6778 0.9944 221125_WJC_METTL3_EV_vs_WT_F06.12165.12165.3 0.00417 Nov-44 R.LK[136.11]AEAELLQQQK[136.11].E sp|Q15149|PLEC_HUMAN 1 1413.8162 2.09 81681 12165 3 1413.811519 472.2794 Plectin OS=Homo sapiens OX=9606 GN=PLEC PE=1 SV=3 6.14 2261.2 - 1.28E+06 - - - -3.3314 - 2.068 0.341 - 139.4 1 2 1 -0.0047 12 0 0 0 7.16E+07 3.43E+07 - - - 4.3545 0.9992 221125_WJC_METTL3_EV_vs_WT_F06.12173.12173.3 0.0039 Oct-60 R.EISNSDGTR[166.11]PVGMLGK[136.11].A "sp|Q9NW64|RBM22_HUMAN,tr|E5RJW4|E5RJW4_HUMAN" 2 1677.8475 0.59 81687 12173 3 1677.84586 560.2898 Pre-mRNA-splicing factor RBM22 OS=Homo sapiens OX=9606 GN=RBM22 PE=1 SV=1 6.17 2262.1 - 3.73E+06 - - - -0.9715 - 1.789 0.31 - 73.8 1 2 0 -0.0016 16 0 0 0 1.15E+08 1.95E+08 - - - 3.4882 1 221125_WJC_METTL3_EV_vs_WT_F06.12174.12174.3 3.42E-06 13/44 R.K[136.11]FGDPVVQSDMK[136.11].H "sp|P0DMV8|HS71A_HUMAN,sp|P0DMV9|HS71B_HUMAN,tr|A0A0G2JIW1|A0A0G2JIW1_HUMAN" 3 1365.6933 0.15 81688 12174 3 1365.694615 456.2384 Heat shock 70 kDa protein 1A OS=Homo sapiens OX=9606 GN=HSPA1A PE=1 SV=1 5.96 2262.1 - 3.34E+06 - - - 0.9358 - 2.569 0.522 - 313.6 1 2 0 0.0013 12 0 0 0 6.25E+07 4.12E+08 - - - 6.9747 0.9999 221125_WJC_METTL3_EV_vs_WT_F06.12175.12175.3 6.23E-07 21/52 K.K[136.11]ITESVAETAQTIK[136.11].K sp|Q96A49|SYAP1_HUMAN 1 1533.8585 1.33 81689 12175 3 1533.85352 512.2934 Synapse-associated protein 1 OS=Homo sapiens OX=9606 GN=SYAP1 PE=1 SV=1 6.14 2262.2 - 1.61E+06 - - - -3.2389 - 3.254 0.526 - 524.1 1 2 0 -0.005 14 0 0 0 2.75E+09 2.07E+09 - - - 7.5386 0.9997 221125_WJC_METTL3_EV_vs_WT_F06.12176.12176.2 0.000428 16-Oct R.LENEIQTYR.S "sp|P13645|K1C10_HUMAN,tr|A0A1B0GVI3|A0A1B0GVI3_HUMAN" 2 1164.5775 7.36 81690 12176 2 1164.579541 583.296 "Keratin, type I cytoskeletal 10 OS=Homo sapiens OX=9606 GN=KRT10 PE=1 SV=6" 4.53 2262.4 - 1.56E+06 - - - 1.7508 - 2.451 0.385 - 338.4 1 2 0 0.002 9 0 0 0 2.31E+07 3.14E+06 - - - 4.4776 1 221125_WJC_METTL3_EV_vs_WT_F06.12178.12178.2 3.12E-11 21/26 K.KITESVAETAQTIK.K sp|Q96A49|SYAP1_HUMAN 1 1517.8301 1.25 81692 12178 2 1517.830753 759.9223 Synapse-associated protein 1 OS=Homo sapiens OX=9606 GN=SYAP1 PE=1 SV=1 6.14 2262.6 - 820239 - - - 0.4381 - 3.859 0.633 - 1226.3 1 2 0 0.0007 14 0 0 0 1.79E+09 1.43E+09 - - - 7.1049 0.9999 221125_WJC_METTL3_EV_vs_WT_F06.12182.12182.3 4.41E-06 Oct-52 R.SSFYPDGGDQETAK.T "sp|Q9NYF8|BCLF1_HUMAN,tr|H0YF00|H0YF00_HUMAN,tr|E9PKI6|E9PKI6_HUMAN,tr|A0A1W2PQ43|A0A1W2PQ43_HUMAN,tr|E9PK91|E9PK91_HUMAN,tr|E9PJA7|E9PJA7_HUMAN,tr|E9PK09|E9PK09_HUMAN,tr|E9PQN2|E9PQN2_HUMAN" 8 1500.6369 2.59 81694 12182 3 1500.633245 501.2196 Bcl-2-associated transcription factor 1 OS=Homo sapiens OX=9606 GN=BCLAF1 PE=1 SV=2 4.03 2263.1 - 3.76E+06 - - - -2.4143 - 1.965 0.547 - 83.5 1 2 0 -0.0036 14 0 0 0 3.07E+08 1.19E+08 - - - 6.4326 0.9998 221125_WJC_METTL3_EV_vs_WT_F06.12183.12183.2 1.55E-06 17/28 K.QLSAQSYGVTSSTAR[166.11].R sp|P49790|NU153_HUMAN 1 1564.7721 1.3 81695 12183 2 1564.769133 783.3933 Nuclear pore complex protein Nup153 OS=Homo sapiens OX=9606 GN=NUP153 PE=1 SV=2 8.75 2263.1 - 5.95E+06 - - - -1.8763 - 3.192 0.494 - 1139.4 1 2 0 -0.0029 15 0 0 0 3.93E+08 3.02E+08 - - - 5.5423 1 221125_WJC_METTL3_EV_vs_WT_F06.12184.12184.2 9.16E-11 24/26 K.K[136.11]ITESVAETAQTIK[136.11].K sp|Q96A49|SYAP1_HUMAN 1 1533.8585 1.25 81696 12184 2 1533.856335 767.9365 Synapse-associated protein 1 OS=Homo sapiens OX=9606 GN=SYAP1 PE=1 SV=1 6.14 2263.2 - 2.19E+06 - - - -1.4036 - 4.512 0.639 - 1653.1 1 2 0 -0.0022 14 0 0 0 1.79E+09 1.43E+09 - - - 7.5411 1 221125_WJC_METTL3_EV_vs_WT_F06.12187.12187.3 3.56E-09 15/52 K.KITESVAETAQTIK.K sp|Q96A49|SYAP1_HUMAN 1 1517.8301 1.33 81697 12187 3 1517.831045 506.9506 Synapse-associated protein 1 OS=Homo sapiens OX=9606 GN=SYAP1 PE=1 SV=1 6.14 2263.6 - 6.07E+06 - - - 0.6305 - 3.418 0.524 - 474.9 1 2 0 0.001 14 0 0 0 2.75E+09 2.07E+09 - - - 7.6481 0.9913 221125_WJC_METTL3_EV_vs_WT_F06.12189.12189.3 0.118 Aug-60 R.EISNSDGTRPVGMLGK.A "sp|Q9NW64|RBM22_HUMAN,tr|E5RJW4|E5RJW4_HUMAN" 2 1659.825 0.59 81698 12189 3 1659.822141 554.2823 Pre-mRNA-splicing factor RBM22 OS=Homo sapiens OX=9606 GN=RBM22 PE=1 SV=1 6.17 2263.8 - 4.01E+06 - - - -1.7345 - 1.431 0.253 - 49.1 2 2 0 -0.0029 16 0 0 0 1.15E+08 1.95E+08 - - - 2.1401 0.9996 221125_WJC_METTL3_EV_vs_WT_F06.12198.12198.2 1.40E-06 26-Nov R.YTPGSSWGESSSGR.L "sp|Q8NDV7|TNR6A_HUMAN,tr|H7C269|H7C269_HUMAN,tr|H3BRT3|H3BRT3_HUMAN" 3 1456.6219 8.23 81703 12198 2 1456.626002 729.3182 Trinucleotide repeat-containing gene 6A protein OS=Homo sapiens OX=9606 GN=TNRC6A PE=1 SV=2 6 2264.9 - 1.35E+06 - - - 2.8257 - 2.296 0.601 - 300.9 1 2 0 0.0041 14 0 0 0 4.97E+07 6.04E+06 - - - 5.5645 1 221125_WJC_METTL3_EV_vs_WT_F06.12205.12205.2 2.72E-05 18/22 R.K[136.11]FGDPVVQSDMK[136.11].H "sp|P0DMV8|HS71A_HUMAN,sp|P0DMV9|HS71B_HUMAN,tr|A0A0G2JIW1|A0A0G2JIW1_HUMAN" 3 1365.6933 0.04 81707 12205 2 1365.692185 683.8539 Heat shock 70 kDa protein 1A OS=Homo sapiens OX=9606 GN=HSPA1A PE=1 SV=1 5.96 2265.8 - 2.67E+06 - - - -0.8435 - 3.21 0.542 - 1018.6 1 2 0 -0.0012 12 0 0 0 7.46E+06 1.95E+08 - - - 6.1125 0.9999 221125_WJC_METTL3_EV_vs_WT_F06.12210.12210.2 2.02E-06 16/22 K.LHGVNINVEASK.N "sp|Q9BWF3|RBM4_HUMAN,sp|Q9BQ04|RBM4B_HUMAN,tr|E9PM61|E9PM61_HUMAN,tr|D6R9K7|D6R9K7_HUMAN,tr|J3QRR5|J3QRR5_HUMAN,tr|E9PB51|E9PB51_HUMAN,tr|U3KQD5|U3KQD5_HUMAN,tr|E9PLB0|E9PLB0_HUMAN" 8 1279.6885 1.82 81710 12210 2 1279.686994 640.8515 RNA-binding protein 4 OS=Homo sapiens OX=9606 GN=RBM4 PE=1 SV=1 6.75 2266.4 - 1.34E+06 - - - -1.1378 - 2.647 0.551 - 847 1 2 0 -0.0015 12 0 0 0 1.12E+07 6.18E+06 - - - 5.6715 0.9997 221125_WJC_METTL3_EV_vs_WT_F06.12213.12213.2 1.61E-06 26-Dec R.YTPGSSWGESSSGR.L "sp|Q8NDV7|TNR6A_HUMAN,tr|H7C269|H7C269_HUMAN,tr|H3BRT3|H3BRT3_HUMAN" 3 1456.6219 8.23 81711 12213 2 1456.618429 729.3182 Trinucleotide repeat-containing gene 6A protein OS=Homo sapiens OX=9606 GN=TNRC6A PE=1 SV=2 6 2266.8 - 1.65E+06 - - - -2.3733 - 2.333 0.551 - 414 1 2 0 -0.0035 14 0 0 0 4.97E+07 6.04E+06 - - - 5.2355 0.9999 221125_WJC_METTL3_EV_vs_WT_F06.12225.12225.3 0.00942 Sep-44 R.KFGDPVVQSDMK.H "sp|P0DMV8|HS71A_HUMAN,sp|P0DMV9|HS71B_HUMAN,tr|A0A0G2JIW1|A0A0G2JIW1_HUMAN" 3 1349.6649 0.15 81717 12225 3 1349.663346 450.8956 Heat shock 70 kDa protein 1A OS=Homo sapiens OX=9606 GN=HSPA1A PE=1 SV=1 5.96 2268.2 - 2.15E+06 - - - -1.1788 - 1.97 0.422 - 132.7 1 2 0 -0.0016 12 0 0 0 6.25E+07 4.12E+08 - - - 5.1238 0.9993 221125_WJC_METTL3_EV_vs_WT_F06.12227.12227.3 2.92E-06 19/68 R.IEDSTGLNR[166.11]PGPAPLSSR[166.11].K "sp|Q9BQ70|TCF25_HUMAN,tr|H3BTU3|H3BTU3_HUMAN,tr|H3BMJ8|H3BMJ8_HUMAN,tr|Q9H7D3|Q9H7D3_HUMAN,tr|H3BS87|H3BS87_HUMAN,tr|H3BQ53|H3BQ53_HUMAN,tr|H3BSP8|H3BSP8_HUMAN" 7 1885.9761 1.13 81718 12227 3 1885.966719 629.666 Transcription factor 25 OS=Homo sapiens OX=9606 GN=TCF25 PE=1 SV=1 6.07 2268.5 - 1.40E+06 - - - -4.9629 - 2.684 0.445 - 445.3 1 2 0 -0.0094 18 0 0 0 6.52E+07 5.76E+07 - - - 5.9572 0.9999 221125_WJC_METTL3_EV_vs_WT_F06.12229.12229.3 4.25E-09 13/52 R.SSFYPDGGDQETAK[136.11].T "sp|Q9NYF8|BCLF1_HUMAN,tr|H0YF00|H0YF00_HUMAN,tr|E9PKI6|E9PKI6_HUMAN,tr|A0A1W2PQ43|A0A1W2PQ43_HUMAN,tr|E9PK91|E9PK91_HUMAN,tr|E9PJA7|E9PJA7_HUMAN,tr|E9PK09|E9PK09_HUMAN,tr|E9PQN2|E9PQN2_HUMAN" 8 1508.6511 2.55 81720 12229 3 1508.64663 503.891 Bcl-2-associated transcription factor 1 OS=Homo sapiens OX=9606 GN=BCLAF1 PE=1 SV=2 4.03 2268.6 - 3.93E+06 - - - -2.9417 - 2.226 0.612 - 160.4 1 2 0 -0.0044 14 0 0 0 3.01E+08 1.18E+08 - - - 7.4885 1 221125_WJC_METTL3_EV_vs_WT_F06.12233.12233.2 2.47E-09 20/32 R.GSGGLGGAC[160.03]GGAGFGSR.S "sp|P48668|K2C6C_HUMAN,sp|P04259|K2C6B_HUMAN,sp|P02538|K2C6A_HUMAN" 3 1423.6263 999 81722 12233 2 1423.622506 712.8204 "Keratin, type II cytoskeletal 6C OS=Homo sapiens OX=9606 GN=KRT6C PE=1 SV=3" 8.25 2269.2 - 3.27E+06 - - - -2.6369 - 3.73 0.627 - 1020 1 2 0 -0.0038 17 0 0 0 8.28E+09 0.00E+00 - - - 6.9073 0.9999 221125_WJC_METTL3_EV_vs_WT_F06.12238.12238.3 5.91E-08 18/40 R.KVLSPYDLTHK.G sp|Q9NX20|RM16_HUMAN 1 1299.7187 0.86 81725 12238 3 1299.715044 434.2468 "39S ribosomal protein L16, mitochondrial OS=Homo sapiens OX=9606 GN=MRPL16 PE=1 SV=1" 8.51 2269.8 - 4.85E+06 - - - -2.8029 - 3.122 0.484 - 547.8 1 2 0 -0.0036 11 0 0 0 1.61E+08 1.88E+08 - - - 7.1693 0.9999 221125_WJC_METTL3_EV_vs_WT_F06.12240.12240.3 8.67E-05 14/40 R.K[136.11]VLSPYDLTHK[136.11].G sp|Q9NX20|RM16_HUMAN 1 1315.7471 0.86 81726 12240 3 1315.745483 439.5896 "39S ribosomal protein L16, mitochondrial OS=Homo sapiens OX=9606 GN=MRPL16 PE=1 SV=1" 8.51 2270 - 4.43E+06 - - - -1.2191 - 2.307 0.431 - 282.8 1 2 0 -0.0016 11 0 0 0 1.61E+08 1.88E+08 - - - 5.7196 0.9999 221125_WJC_METTL3_EV_vs_WT_F06.12241.12241.2 0.000142 20-Oct K.NQC[160.03]LFTNTQC[160.03]K.V "sp|Q9UL40|ZN346_HUMAN,tr|B7Z6B6|B7Z6B6_HUMAN,tr|D6RJ07|D6RJ07_HUMAN,tr|B7Z6Q2|B7Z6Q2_HUMAN" 4 1412.6177 1.03 81727 12241 2 1412.617266 707.3161 Zinc finger protein 346 OS=Homo sapiens OX=9606 GN=ZNF346 PE=1 SV=1 8.06 2270.1 - 1.60E+06 - - - -0.286 - 2.433 0.535 - 456.9 1 2 0 -0.0004 11 0 0 0 4.89E+07 4.74E+07 - - - 5.3977 1 221125_WJC_METTL3_EV_vs_WT_F06.12243.12243.2 5.10E-07 13/22 R.EDITQSAQHALR[166.11].L sp|Q12906|ILF3_HUMAN 1 1377.6876 1.6 81729 12243 2 1377.682991 689.8511 Interleukin enhancer-binding factor 3 OS=Homo sapiens OX=9606 GN=ILF3 PE=1 SV=3 5.32 2270.4 - 1.68E+06 - - - -3.3534 - 2.846 0.547 - 774.4 1 2 0 -0.0046 12 0 0 0 7.06E+07 4.42E+07 - - - 5.8317 1 221125_WJC_METTL3_EV_vs_WT_F06.12245.12245.2 2.58E-08 17/20 K.HSSGC[160.03]AFLSVK.K "sp|O15392|BIRC5_HUMAN,tr|A0A0B4J1S3|A0A0B4J1S3_HUMAN,tr|K7EMW2|K7EMW2_HUMAN,tr|H3BLT4|H3BLT4_HUMAN" 4 1191.5706 1.86 81731 12245 2 1191.571571 596.7926 Baculoviral IAP repeat-containing protein 5 OS=Homo sapiens OX=9606 GN=BIRC5 PE=1 SV=3 8.23 2270.6 - 1.40E+06 - - - 0.7788 - 2.872 0.628 - 732 1 2 0 0.0009 11 0 0 0 2.63E+08 1.41E+08 - - - 6.5332 0.9999 221125_WJC_METTL3_EV_vs_WT_F06.12250.12250.3 1.10E-05 13/52 R.LISQDIHSNTYNYK[136.11].S "sp|Q96D46|NMD3_HUMAN,tr|C9JA08|C9JA08_HUMAN" 2 1702.8406 0.65 81734 12250 3 1702.838791 568.6208 60S ribosomal export protein NMD3 OS=Homo sapiens OX=9606 GN=NMD3 PE=1 SV=1 6.74 2271.3 - 1.83E+06 - - - -1.0623 - 2.353 0.401 - 127.5 1 2 0 -0.0018 14 0 0 0 2.47E+07 3.77E+07 - - - 5.2843 1 221125_WJC_METTL3_EV_vs_WT_F06.12252.12252.2 7.59E-07 13/22 R.EIVHLQAGQC[160.03]GN.Q "sp|P04350|TBB4A_HUMAN,sp|Q9BVA1|TBB2B_HUMAN,sp|P07437|TBB5_HUMAN,sp|Q13509|TBB3_HUMAN,sp|Q13885|TBB2A_HUMAN,sp|P68371|TBB4B_HUMAN,sp|Q9BUF5|TBB6_HUMAN,tr|K7EJZ4|K7EJZ4_HUMAN,tr|M0R2D3|M0R2D3_HUMAN,tr|G3V3W7|G3V3W7_HUMAN,tr|K7EQT3|K7EQT3_HUMAN,tr|K7EN98|K7EN98_HUMAN,tr|M0R2T4|M0R2T4_HUMAN,tr|G3V3R4|G3V3R4_HUMAN,tr|M0R042|M0R042_HUMAN,tr|M0QY85|M0QY85_HUMAN,tr|M0QZL7|M0QZL7_HUMAN,tr|K7ESM5|K7ESM5_HUMAN,tr|G3V5W4|G3V5W4_HUMAN,tr|M0R0X0|M0R0X0_HUMAN,tr|K7ERA8|K7ERA8_HUMAN,tr|M0QYM7|M0QYM7_HUMAN,tr|K7ESQ3|K7ESQ3_HUMAN,tr|G3V4U2|G3V4U2_HUMAN,tr|M0R278|M0R278_HUMAN,tr|K7EL29|K7EL29_HUMAN,tr|M0QY37|M0QY37_HUMAN,tr|G3V2R8|G3V2R8_HUMAN,tr|G3V3J6|G3V3J6_HUMAN,tr|M0QX14|M0QX14_HUMAN,tr|K7EPE5|K7EPE5_HUMAN,tr|G3V2N6|G3V2N6_HUMAN,tr|K7EJ64|K7EJ64_HUMAN" 33 1324.6194 - 81736 12252 2 1324.621684 663.317 Tubulin beta-4A chain OS=Homo sapiens OX=9606 GN=TUBB4A PE=1 SV=2 5.24 2271.5 - 1.42E+06 - - - 1.7363 - 2.862 0.562 - 567.8 1 1 0 0.0023 12 0 0 0 - - - - - 5.9579 0.9999 221125_WJC_METTL3_EV_vs_WT_F06.12254.12254.3 0.000357 13/48 K.GGHFYSAK[136.11]PEILR[166.11].A "sp|P52701|MSH6_HUMAN,tr|A0A494C0M1|A0A494C0M1_HUMAN,tr|C9J7Y7|C9J7Y7_HUMAN,tr|C9JH55|C9JH55_HUMAN,tr|C9J8Y8|C9J8Y8_HUMAN,tr|A0A087WWJ1|A0A087WWJ1_HUMAN" 6 1491.7953 1.29 81738 12254 3 1491.794834 498.2724 DNA mismatch repair protein Msh6 OS=Homo sapiens OX=9606 GN=MSH6 PE=1 SV=2 8.6 2271.8 - 1.11E+06 - - - -0.3244 - 1.83 0.445 - 129.3 1 2 0 -0.0005 13 0 0 0 1.77E+07 1.38E+07 - - - 5.1397 0.9995 221125_WJC_METTL3_EV_vs_WT_F06.12257.12257.3 0.00213 17/68 R.IEDSTGLNRPGPAPLSSR.K "sp|Q9BQ70|TCF25_HUMAN,tr|H3BTU3|H3BTU3_HUMAN,tr|H3BMJ8|H3BMJ8_HUMAN,tr|Q9H7D3|Q9H7D3_HUMAN,tr|H3BS87|H3BS87_HUMAN,tr|H3BQ53|H3BQ53_HUMAN,tr|H3BSP8|H3BSP8_HUMAN" 7 1865.9595 1.13 81739 12257 3 1865.957861 622.9938 Transcription factor 25 OS=Homo sapiens OX=9606 GN=TCF25 PE=1 SV=1 6.07 2272.2 - 2.90E+06 - - - -0.8993 - 2.032 0.313 - 134.8 1 2 0 -0.0017 18 0 0 0 6.52E+07 5.76E+07 - - - 3.7947 1 221125_WJC_METTL3_EV_vs_WT_F06.12258.12258.2 6.14E-06 16/20 K.HSSGC[160.03]AFLSVK[136.11].K "sp|O15392|BIRC5_HUMAN,tr|A0A0B4J1S3|A0A0B4J1S3_HUMAN,tr|K7EMW2|K7EMW2_HUMAN,tr|H3BLT4|H3BLT4_HUMAN" 4 1199.5848 1.86 81740 12258 2 1199.588264 600.7997 Baculoviral IAP repeat-containing protein 5 OS=Homo sapiens OX=9606 GN=BIRC5 PE=1 SV=3 8.23 2272.3 - 3.00E+06 - - - 2.8518 - 2.891 0.588 - 590.2 1 2 0 0.0034 11 0 0 0 2.63E+08 1.41E+08 - - - 6.2548 0.9967 221125_WJC_METTL3_EV_vs_WT_F06.12262.12262.3 7.02E-07 Nov-40 K.HSSGC[160.03]AFLSVK[136.11].K "sp|O15392|BIRC5_HUMAN,tr|A0A0B4J1S3|A0A0B4J1S3_HUMAN,tr|K7EMW2|K7EMW2_HUMAN,tr|H3BLT4|H3BLT4_HUMAN" 4 1199.5848 1.99 81742 12262 3 1199.594212 400.8689 Baculoviral IAP repeat-containing protein 5 OS=Homo sapiens OX=9606 GN=BIRC5 PE=1 SV=3 8.23 2272.7 - 3.15E+06 - - - 7.8102 - 2.239 0.479 - 136.3 1 2 0 0.0094 11 0 0 0 1.65E+08 8.28E+07 - - - 6.1676 1 221125_WJC_METTL3_EV_vs_WT_F06.12263.12263.3 1.06E-08 Oct-48 R.LHNLAQFEGGESK.V "sp|Q9Y4A5|TRRAP_HUMAN,tr|A0A2R8YFJ4|A0A2R8YFJ4_HUMAN,tr|H0Y4W2|H0Y4W2_HUMAN,tr|F2Z2U4|F2Z2U4_HUMAN" 4 1428.6997 1.8 81743 12263 3 1428.701471 477.2405 Transformation\transcription domain-associated protein OS=Homo sapiens OX=9606 GN=TRRAP PE=1 SV=3 5.4 2272.8 - 2.29E+06 - - - 1.2095 - 2.424 0.536 - 142.3 1 2 0 0.0017 13 0 0 0 4.75E+07 2.63E+07 - - - 6.916 0.9998 221125_WJC_METTL3_EV_vs_WT_F06.12266.12266.3 0.00129 Nov-36 R.LKYENEVALR.Q "sp|P13645|K1C10_HUMAN,tr|A0A1B0GVI3|A0A1B0GVI3_HUMAN" 2 1233.6717 190.19 81746 12266 3 1233.671324 412.2312 "Keratin, type I cytoskeletal 10 OS=Homo sapiens OX=9606 GN=KRT10 PE=1 SV=6" 6.14 2273 - 1.54E+06 - - - -0.3348 - 2.422 0.45 - 160.6 1 2 1 -0.0004 10 0 0 0 3.69E+08 1.94E+06 - - - 6.1403 0.986 221125_WJC_METTL3_EV_vs_WT_F06.12268.12268.3 0.298 Oct-40 K.KLSVPASVVSR.L "sp|Q8IWZ3|ANKH1_HUMAN,tr|A0A0A0MQZ8|A0A0A0MQZ8_HUMAN,tr|H0Y472|H0Y472_HUMAN,tr|H0Y7Y3|H0Y7Y3_HUMAN,tr|H0Y4P6|H0Y4P6_HUMAN,tr|H0Y785|H0Y785_HUMAN" 6 1141.6819 1.56 81748 12268 3 1141.680957 381.5679 Ankyrin repeat and KH domain-containing protein 1 OS=Homo sapiens OX=9606 GN=ANKHD1 PE=1 SV=1 11 2273.3 - 623036 - - - -0.833 - 1.486 0.174 - 100.9 1 2 0 -0.001 11 0 0 0 5.76E+06 3.70E+06 - - - 1.6049 0.9846 221125_WJC_METTL3_EV_vs_WT_F06.12270.12270.2 0.00182 16-Oct R.K[136.11]IELFGR[166.11]PH.N sp|Q86U44|MTA70_HUMAN 1 1113.6414 0 81749 12270 2 1113.640249 557.828 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 8.75 2273.5 - 3.73E+06 - - - -1.0183 - 2.062 0.386 - 350.8 1 1 0 -0.0011 9 0 0 0 1.17E+06 2.05E+09 - - - 3.9853 0.9999 221125_WJC_METTL3_EV_vs_WT_F06.12272.12272.3 0.000292 13/64 R.GSGGLGGAC[160.03]GGAGFGSR.S "sp|P48668|K2C6C_HUMAN,sp|P04259|K2C6B_HUMAN,sp|P02538|K2C6A_HUMAN" 3 1423.6263 1595.58 81750 12272 3 1423.623422 475.5494 "Keratin, type II cytoskeletal 6C OS=Homo sapiens OX=9606 GN=KRT6C PE=1 SV=3" 8.25 2273.7 - 3.01E+06 - - - -1.9935 - 2.353 0.486 - 207.4 1 2 0 -0.0028 17 0 0 0 2.16E+08 1.35E+05 - - - 6.1194 0.9996 221125_WJC_METTL3_EV_vs_WT_F06.12273.12273.3 0.00612 Nov-52 K.K[136.11]ITESVAETAQTIK.K sp|Q96A49|SYAP1_HUMAN 1 1525.8443 - 81751 12273 3 1525.844144 509.622 Synapse-associated protein 1 OS=Homo sapiens OX=9606 GN=SYAP1 PE=1 SV=1 6.14 2273.7 - 1.78E+06 - - - -0.0944 - 1.918 0.328 - 127.2 1 2 0 -0.0001 14 0 0 0 - - - - - 3.9276 0.9995 221125_WJC_METTL3_EV_vs_WT_F06.12276.12276.2 0.000744 20-Nov K.SGVQVFQQSSR[166.11].G "sp|Q8IZH2|XRN1_HUMAN,tr|H7C5E4|H7C5E4_HUMAN" 2 1231.6185 1.41 81754 12276 2 1231.615928 616.8165 5'-3' exoribonuclease 1 OS=Homo sapiens OX=9606 GN=XRN1 PE=1 SV=1 9.47 2274.1 - 709840 - - - -2.0631 - 2.118 0.404 - 456.2 1 2 0 -0.0025 11 0 0 0 7.90E+07 5.59E+07 - - - 4.0544 0.9999 221125_WJC_METTL3_EV_vs_WT_F06.12281.12281.2 2.03E-07 13/16 K.HGINC[160.03]FINR[166.11].Q "sp|P78371|TCPB_HUMAN,tr|F8VQ14|F8VQ14_HUMAN,tr|F5GWF6|F5GWF6_HUMAN" 3 1139.5534 0.36 81757 12281 2 1139.553102 570.784 T-complex protein 1 subunit beta OS=Homo sapiens OX=9606 GN=CCT2 PE=1 SV=4 8.26 2274.7 - 1.32E+06 - - - -0.2325 - 2.314 0.544 - 456.1 1 2 0 -0.0003 9 0 0 0 1.56E+07 4.31E+07 - - - 5.4861 0.9999 221125_WJC_METTL3_EV_vs_WT_F06.12285.12285.3 0.00398 13/52 R.IEDVTPIPSDSTR[166.11]R[166.11].K "sp|P62263|RS14_HUMAN,tr|A0A2R8Y811|A0A2R8Y811_HUMAN" 2 1604.8273 1.35 81760 12285 3 1604.828407 535.9497 40S ribosomal protein S14 OS=Homo sapiens OX=9606 GN=RPS14 PE=1 SV=3 4.56 2275.1 - 4.17E+06 - - - 0.696 - 2.839 0.406 - 291.9 1 2 0 0.0011 14 0 0 0 2.25E+09 1.66E+09 - - - 5.8392 0.9987 221125_WJC_METTL3_EV_vs_WT_F06.12286.12286.2 8.41E-06 18-Nov R.LKYENEVALR.Q "sp|P13645|K1C10_HUMAN,tr|A0A1B0GVI3|A0A1B0GVI3_HUMAN" 2 1233.6717 999 81761 12286 2 1233.671583 617.8431 "Keratin, type I cytoskeletal 10 OS=Homo sapiens OX=9606 GN=KRT10 PE=1 SV=6" 6.14 2275.2 - 1.39E+06 - - - -0.1248 - 2.272 0.492 - 297.9 1 2 1 -0.0002 10 0 0 0 7.44E+07 0.00E+00 - - - 4.9656 0.9904 221125_WJC_METTL3_EV_vs_WT_F06.12289.12289.3 0.000236 14/60 M.APVPLDDSNRPASLTK.D "sp|Q9NYF8|BCLF1_HUMAN,tr|E9PKI6|E9PKI6_HUMAN,tr|A0A1W2PQ43|A0A1W2PQ43_HUMAN,tr|E9PK91|E9PK91_HUMAN,tr|E9PJA7|E9PJA7_HUMAN,tr|E9PK09|E9PK09_HUMAN,tr|E9PQN2|E9PQN2_HUMAN" 7 1679.8842 5.47 81764 12289 3 1679.885122 560.9687 Bcl-2-associated transcription factor 1 OS=Homo sapiens OX=9606 GN=BCLAF1 PE=1 SV=2 6 2275.6 - 649795 - - - 0.5197 - 2.37 0.405 - 193.6 1 1 0 0.0009 16 0 0 0 1.46E+07 2.67E+06 - - - 5.2692 0.9948 221125_WJC_METTL3_EV_vs_WT_F06.12292.12292.2 0.191 18-Sep R.DK[136.11]ELEGLQVK[136.11].L sp|P40222|TXLNA_HUMAN 1 1173.6576 1.15 81765 12292 2 1173.657105 587.8361 Alpha-taxilin OS=Homo sapiens OX=9606 GN=TXLNA PE=1 SV=3 4.68 2276 - 793216 - - - -0.4243 - 1.816 0.326 - 238.5 1 2 1 -0.0005 10 0 0 0 1.21E+07 1.05E+07 - - - 3.1141 0.8297 221125_WJC_METTL3_EV_vs_WT_F06.12293.12293.2 0.0125 22-Jul K.DK[136.11]GGPEFSSALK[136.11].N "sp|Q9NY61|AATF_HUMAN,tr|A0A7P0T868|A0A7P0T868_HUMAN,tr|A0A7P0TAR0|A0A7P0TAR0_HUMAN,tr|A0A7P0TBG4|A0A7P0TBG4_HUMAN,tr|A0A7P0TBI0|A0A7P0TBI0_HUMAN,tr|A0A7P0Z4P2|A0A7P0Z4P2_HUMAN,tr|A0A7P0Z4N2|A0A7P0Z4N2_HUMAN,tr|A0A7P0Z434|A0A7P0Z434_HUMAN" 8 1250.6478 1.38 81766 12293 2 1250.643301 626.3312 Protein AATF OS=Homo sapiens OX=9606 GN=AATF PE=1 SV=1 6.07 2276.1 - 652061 - - - -3.5709 - 1.58 0.197 - 103.4 2 2 1 -0.0045 12 0 0 0 1.40E+07 1.01E+07 - - - 1.5637 1 221125_WJC_METTL3_EV_vs_WT_F06.12298.12298.3 6.12E-06 16/52 R.IEDVTPIPSDSTRR.K "sp|P62263|RS14_HUMAN,tr|A0A2R8Y811|A0A2R8Y811_HUMAN" 2 1584.8108 1.36 81769 12298 3 1584.81101 529.2775 40S ribosomal protein S14 OS=Homo sapiens OX=9606 GN=RPS14 PE=1 SV=3 4.56 2276.8 - 9.59E+06 - - - 0.1641 - 3.08 0.425 - 461.3 1 2 0 0.0003 14 0 0 0 2.25E+09 1.66E+09 - - - 6.2678 0.9948 221125_WJC_METTL3_EV_vs_WT_F06.12301.12301.3 0.0242 Sep-36 R.DK[136.11]ELEGLQVK[136.11].L sp|P40222|TXLNA_HUMAN 1 1173.6576 1.18 81772 12301 3 1173.656909 392.2265 Alpha-taxilin OS=Homo sapiens OX=9606 GN=TXLNA PE=1 SV=3 4.68 2277 - 1.31E+06 - - - -0.5913 - 1.845 0.259 - 109 1 2 1 -0.0007 10 0 0 0 2.65E+07 2.25E+07 - - - 3.2161 0.9987 221125_WJC_METTL3_EV_vs_WT_F06.12304.12304.2 0.0203 12-Jul R.LAADDFR.T "sp|Q04695|K1C17_HUMAN,sp|P13645|K1C10_HUMAN,sp|O76015|KRT38_HUMAN,sp|Q2M2I5|K1C24_HUMAN,sp|Q15323|K1H1_HUMAN,sp|P02533|K1C14_HUMAN,sp|P05783|K1C18_HUMAN,sp|P08727|K1C19_HUMAN,sp|P08779|K1C16_HUMAN,sp|Q7Z3Y7|K1C28_HUMAN,sp|Q14532|K1H2_HUMAN,sp|P19012|K1C15_HUMAN,sp|O76013|KRT36_HUMAN,sp|Q14525|KT33B_HUMAN,sp|Q92764|KRT35_HUMAN,sp|O76014|KRT37_HUMAN,sp|P13646|K1C13_HUMAN,tr|F8VZY9|F8VZY9_HUMAN,tr|K7EPJ9|K7EPJ9_HUMAN,tr|C9JM50|C9JM50_HUMAN,tr|A0A1B0GVI3|A0A1B0GVI3_HUMAN,tr|K7EMD9|K7EMD9_HUMAN,tr|F5GWP8|F5GWP8_HUMAN,tr|K7ERE3|K7ERE3_HUMAN,tr|C4AM86|C4AM86_HUMAN" 25 806.3923 61.44 81774 12304 2 806.391532 404.2034 "Keratin, type I cytoskeletal 17 OS=Homo sapiens OX=9606 GN=KRT17 PE=1 SV=2" 4.21 2277.4 - 2.42E+06 - - - -0.9115 - 1.555 0.251 - 179.1 1 2 0 -0.0007 7 0 0 0 5.30E+07 8.62E+05 - - - 2.2935 0.9984 221125_WJC_METTL3_EV_vs_WT_F06.12306.12306.3 2.66E-06 Dec-44 K.DK[136.11]GGPEFSSALK[136.11].N "sp|Q9NY61|AATF_HUMAN,tr|A0A7P0T868|A0A7P0T868_HUMAN,tr|A0A7P0TAR0|A0A7P0TAR0_HUMAN,tr|A0A7P0TBG4|A0A7P0TBG4_HUMAN,tr|A0A7P0TBI0|A0A7P0TBI0_HUMAN,tr|A0A7P0Z4P2|A0A7P0Z4P2_HUMAN,tr|A0A7P0Z4N2|A0A7P0Z4N2_HUMAN,tr|A0A7P0Z434|A0A7P0Z434_HUMAN" 8 1250.6478 1.01 81775 12306 3 1250.645776 417.8899 Protein AATF OS=Homo sapiens OX=9606 GN=AATF PE=1 SV=1 6.07 2277.6 - 1.25E+06 - - - -1.592 - 2.264 0.319 - 130.8 1 2 1 -0.002 12 0 0 0 2.46E+07 2.45E+07 - - - 4.361 0.9994 221125_WJC_METTL3_EV_vs_WT_F06.12307.12307.2 0.00921 14/26 R.IEDVTPIPSDSTRR.K "sp|P62263|RS14_HUMAN,tr|A0A2R8Y811|A0A2R8Y811_HUMAN" 2 1584.8108 1.28 81776 12307 2 1584.813206 793.4127 40S ribosomal protein S14 OS=Homo sapiens OX=9606 GN=RPS14 PE=1 SV=3 4.56 2277.7 - 1.07E+06 - - - 1.5497 - 2.067 0.337 - 291.3 1 2 0 0.0025 14 0 0 0 9.28E+07 7.25E+07 - - - 3.3514 0.9786 221125_WJC_METTL3_EV_vs_WT_F06.12308.12308.3 0.013 15/60 C.SAGLGALAQRPGSVSK.W "sp|Q9NXV2|KCTD5_HUMAN,tr|H3BSS5|H3BSS5_HUMAN" 2 1497.8263 0.85 81777 12308 3 1497.825137 500.2827 BTB\POZ domain-containing protein KCTD5 OS=Homo sapiens OX=9606 GN=KCTD5 PE=1 SV=1 11 2277.9 - 1.73E+06 - - - -0.8032 - 2.628 0.315 - 246.7 1 1 0 -0.0012 16 0 0 0 2.68E+07 3.14E+07 - - - 4.5308 1 221125_WJC_METTL3_EV_vs_WT_F06.12309.12309.3 8.61E-09 24/60 R.YSGAYGASVSDEELKR.R "sp|Q9NX63|MIC19_HUMAN,tr|A0A286YEX5|A0A286YEX5_HUMAN,tr|F8WAR4|F8WAR4_HUMAN,tr|C9JRZ6|C9JRZ6_HUMAN" 4 1730.8111 1.97 81778 12309 3 1730.810864 577.9443 MICOS complex subunit MIC19 OS=Homo sapiens OX=9606 GN=CHCHD3 PE=1 SV=1 4.68 2278 - 990628 - - - -0.1618 - 4.288 0.653 - 507.4 1 2 0 -0.0003 16 0 0 0 7.25E+07 3.67E+07 - - - 9.5557 0.9998 221125_WJC_METTL3_EV_vs_WT_F06.12313.12313.3 0.0185 Nov-32 K.HGINC[160.03]FINR[166.11].Q "sp|P78371|TCPB_HUMAN,tr|F8VQ14|F8VQ14_HUMAN,tr|F5GWF6|F5GWF6_HUMAN" 3 1139.5534 0.001 81780 12313 3 1139.553789 380.8584 T-complex protein 1 subunit beta OS=Homo sapiens OX=9606 GN=CCT2 PE=1 SV=4 8.26 2278.4 - 1.50E+06 - - - 0.3703 - 1.951 0.345 - 165.1 1 2 0 0.0004 9 0 0 0 0.00E+00 2.20E+07 - - - 4.4005 0.9935 221125_WJC_METTL3_EV_vs_WT_F06.12315.12315.2 0.00251 20-Nov K.SGVQVFQQSSR.G "sp|Q8IZH2|XRN1_HUMAN,tr|H7C5E4|H7C5E4_HUMAN" 2 1221.6102 1.62 81782 12315 2 1221.606378 611.8124 5'-3' exoribonuclease 1 OS=Homo sapiens OX=9606 GN=XRN1 PE=1 SV=1 9.47 2278.5 - 4.03E+06 - - - -3.1278 - 1.999 0.164 - 354.7 1 2 0 -0.0038 11 0 0 0 7.90E+07 4.86E+07 - - - 2.1249 0.9999 221125_WJC_METTL3_EV_vs_WT_F06.12316.12316.3 4.92E-06 23/60 R.YSGAYGASVSDEELK[136.11]R[166.11].R "sp|Q9NX63|MIC19_HUMAN,tr|A0A286YEX5|A0A286YEX5_HUMAN,tr|F8WAR4|F8WAR4_HUMAN,tr|C9JRZ6|C9JRZ6_HUMAN" 4 1748.8336 1.99 81783 12316 3 1748.839807 583.9518 MICOS complex subunit MIC19 OS=Homo sapiens OX=9606 GN=CHCHD3 PE=1 SV=1 4.68 2278.7 - 1.20E+06 - - - 3.5412 - 2.839 0.507 - 341.8 1 2 0 0.0062 16 0 0 0 7.20E+07 3.62E+07 - - - 6.8682 0.9989 221125_WJC_METTL3_EV_vs_WT_F06.12321.12321.3 5.97E-08 Dec-44 R.STSHK[136.11]PDEIYGM.L sp|Q86U44|MTA70_HUMAN 1 1371.622 0.02 81786 12321 3 1371.621338 458.2146 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 5.3 2279.2 - 6.90E+06 - - - -0.4943 - 2.609 0.628 - 172.8 1 1 0 -0.0007 12 0 0 0 3.73E+07 1.83E+09 - - - 8.1995 0.9904 221125_WJC_METTL3_EV_vs_WT_F06.12322.12322.2 3.00E-06 22-Nov R.STSHK[136.11]PDEIYGM.L sp|Q86U44|MTA70_HUMAN 1 1371.622 0.02 81787 12322 2 1371.623795 686.8183 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 5.3 2279.3 - 2.02E+06 - - - 1.297 - 2.08 0.563 - 286.6 1 1 0 0.0018 12 0 0 0 9.83E+06 6.46E+08 - - - 5.1257 1 221125_WJC_METTL3_EV_vs_WT_F06.12323.12323.2 1.27E-10 13/26 R.DNASGASVVAIDNK.L tr|Q5JRJ0|Q5JRJ0_HUMAN 1 1359.663 0.25 81788 12323 2 1359.6634 680.8388 TSC22 domain family protein 3 OS=Homo sapiens OX=9606 GN=TSC22D3 PE=1 SV=1 4.21 2279.4 - 779066 - - - 0.2773 - 2.709 0.676 - 517.2 1 2 0 0.0004 14 0 0 0 1.24E+07 5.02E+07 - - - 6.5347 0.9999 221125_WJC_METTL3_EV_vs_WT_F06.12324.12324.3 0.000593 17/52 R.IEDVTPIPSDSTRR[166.11].K "sp|P62263|RS14_HUMAN,tr|A0A2R8Y811|A0A2R8Y811_HUMAN" 2 1594.819 - 81789 12324 3 1594.81609 532.6136 40S ribosomal protein S14 OS=Homo sapiens OX=9606 GN=RPS14 PE=1 SV=3 4.56 2279.6 - 719441 - - - -1.8372 - 3.202 0.343 - 366.6 1 2 0 -0.0029 14 0 0 0 - - - - - 5.4561 0.9998 221125_WJC_METTL3_EV_vs_WT_F06.12326.12326.3 0.000382 15/48 R.LSNRPAFMPSEGK.M "sp|O43707|ACTN4_HUMAN,sp|P35609|ACTN2_HUMAN,tr|A0A494C1A0|A0A494C1A0_HUMAN,tr|F5GXS2|F5GXS2_HUMAN,tr|A0A804HI95|A0A804HI95_HUMAN,tr|H7C144|H7C144_HUMAN" 6 1432.7133 2 81791 12326 3 1432.708932 478.5784 Alpha-actinin-4 OS=Homo sapiens OX=9606 GN=ACTN4 PE=1 SV=2 8.75 2279.8 - 792458 - - - -3.0376 - 2.705 0.442 - 321.3 1 2 0 -0.0044 13 0 0 0 2.25E+07 1.13E+07 - - - 6.1647 0.9939 221125_WJC_METTL3_EV_vs_WT_F06.12330.12330.3 1.59E-05 Dec-48 R.LHNFHQLSAPQPC[160.03].F "sp|O14744|ANM5_HUMAN,tr|H0YJD3|H0YJD3_HUMAN,tr|H7BZ44|H7BZ44_HUMAN" 3 1547.7303 - 81793 12330 3 1547.731101 516.9174 Protein arginine N-methyltransferase 5 OS=Homo sapiens OX=9606 GN=PRMT5 PE=1 SV=4 6.91 2280.3 - 4.98E+06 - - - 0.4975 - 2.296 0.443 - 165.9 1 1 0 0.0008 13 0 0 0 - - - - - 5.7323 0.98 221125_WJC_METTL3_EV_vs_WT_F06.12331.12331.3 0.000128 Dec-44 K.STEHNMGLALTR.N sp|Q10469|MGAT2_HUMAN 1 1328.6507 1.3 81794 12331 3 1328.645879 443.8908 "Alpha-1,6-mannosyl-glycoprotein 2-beta-N-acetylglucosaminyltransferase OS=Homo sapiens OX=9606 GN=MGAT2 PE=1 SV=1" 6.47 2280.4 - 1.93E+06 - - - -3.6165 - 2.206 0.156 - 268.4 1 2 0 -0.0048 12 0 0 0 3.11E+07 2.38E+07 - - - 2.471 1 221125_WJC_METTL3_EV_vs_WT_F06.12336.12336.3 5.97E-08 16/48 R.K[136.11]NPLPPSVGVVDK[136.11].K sp|Q8NC51|PAIRB_HUMAN 1 1364.7999 1.35 81798 12336 3 1364.798111 455.9406 Plasminogen activator inhibitor 1 RNA-binding protein OS=Homo sapiens OX=9606 GN=SERBP1 PE=1 SV=2 8.59 2281 - 1.43E+06 - - - -1.2749 - 3.412 0.533 - 399.1 1 2 0 -0.0017 13 0 0 0 3.89E+07 2.88E+07 - - - 7.8095 0.9997 221125_WJC_METTL3_EV_vs_WT_F06.12338.12338.2 0.00063 26-Sep R.IEDVTPIPSDSTR[166.11]R[166.11].K "sp|P62263|RS14_HUMAN,tr|A0A2R8Y811|A0A2R8Y811_HUMAN" 2 1604.8273 1.29 81799 12338 2 1604.827673 803.4209 40S ribosomal protein S14 OS=Homo sapiens OX=9606 GN=RPS14 PE=1 SV=3 4.56 2281.2 - 4.54E+06 - - - 0.2387 - 1.774 0.404 - 97.5 1 2 0 0.0004 14 0 0 0 1.04E+08 8.07E+07 - - - 3.4633 1 221125_WJC_METTL3_EV_vs_WT_F06.12339.12339.2 1.11E-09 17/28 K.ETSTLQVEQNGDYGR.G "sp|Q71RC2|LARP4_HUMAN,tr|Q96J85|Q96J85_HUMAN,tr|X6RLN4|X6RLN4_HUMAN" 3 1695.77 1.55 81800 12339 2 1695.771216 848.8923 La-related protein 4 OS=Homo sapiens OX=9606 GN=LARP4 PE=1 SV=3 4.14 2281.3 - 957299 - - - 0.713 - 3.29 0.628 - 1102.2 1 2 0 0.0012 15 0 0 0 2.31E+07 1.49E+07 - - - 6.6069 0.9999 221125_WJC_METTL3_EV_vs_WT_F06.12340.12340.2 1.19E-06 13/22 K.SSGTNFQGLPSK[136.11].L "sp|Q68EM7|RHG17_HUMAN,tr|C9IZD3|C9IZD3_HUMAN" 2 1229.6132 1.23 81801 12340 2 1229.613958 615.8139 Rho GTPase-activating protein 17 OS=Homo sapiens OX=9606 GN=ARHGAP17 PE=1 SV=1 8.47 2281.4 - 4.07E+06 - - - 0.6441 - 2.513 0.504 - 474.1 1 2 0 0.0008 12 0 0 0 1.67E+08 1.35E+08 - - - 5.1879 0.9998 221125_WJC_METTL3_EV_vs_WT_F06.12341.12341.3 5.66E-07 13/44 K.YNPDKHYIYVVR.L sp|O00443|P3C2A_HUMAN 1 1565.7991 0.5 81802 12341 3 1565.799575 522.9403 Phosphatidylinositol 4-phosphate 3-kinase C2 domain-containing subunit alpha OS=Homo sapiens OX=9606 GN=PIK3C2A PE=1 SV=2 8.44 2281.5 - 1.37E+06 - - - 0.327 - 2.328 0.469 - 187.4 1 2 1 0.0005 12 0 0 0 2.55E+07 5.12E+07 - - - 6.111 0.9964 221125_WJC_METTL3_EV_vs_WT_F06.12343.12343.4 0.000655 Nov-66 K.YNPDKHYIYVVR.L sp|O00443|P3C2A_HUMAN 1 1565.7991 1.05 81804 12343 4 1565.797882 392.457 Phosphatidylinositol 4-phosphate 3-kinase C2 domain-containing subunit alpha OS=Homo sapiens OX=9606 GN=PIK3C2A PE=1 SV=2 8.44 2281.7 - 830068 - - - -0.7542 - 2.125 0.297 - 64.2 1 2 1 -0.0012 12 0 0 0 1.22E+07 1.16E+07 - - - 2.096 1 221125_WJC_METTL3_EV_vs_WT_F06.12344.12344.2 1.81E-12 17/28 K.ETSTLQVEQNGDYGR[166.11].G "sp|Q71RC2|LARP4_HUMAN,tr|Q96J85|Q96J85_HUMAN,tr|X6RLN4|X6RLN4_HUMAN" 3 1705.7783 1.52 81805 12344 2 1705.770465 853.8964 La-related protein 4 OS=Homo sapiens OX=9606 GN=LARP4 PE=1 SV=3 4.14 2281.8 - 788192 - - - -4.5797 - 3.226 0.68 - 1119.4 1 2 0 -0.0078 15 0 0 0 2.27E+07 1.49E+07 - - - 6.9406 0.9913 221125_WJC_METTL3_EV_vs_WT_F06.12346.12346.2 2.17E-06 14/24 L.EDVTPIPSDSTRR.K "sp|P62263|RS14_HUMAN,tr|A0A2R8Y811|A0A2R8Y811_HUMAN" 2 1471.7267 1.32 81807 12346 2 1471.724595 736.8706 40S ribosomal protein S14 OS=Homo sapiens OX=9606 GN=RPS14 PE=1 SV=3 4.56 2282.1 - 585034 - - - -1.4208 - 2.393 0.538 - 399.5 1 1 0 -0.0021 13 0 0 0 1.59E+07 1.21E+07 - - - 5.2534 1 221125_WJC_METTL3_EV_vs_WT_F06.12353.12353.2 1.13E-08 17/28 R.VTSVGTGNFSSSVSK[136.11].V sp|Q5T3J3|LRIF1_HUMAN 1 1463.7347 1.29 81812 12353 2 1463.738125 732.8746 Ligand-dependent nuclear receptor-interacting factor 1 OS=Homo sapiens OX=9606 GN=LRIF1 PE=1 SV=1 8.72 2282.8 - 2.27E+06 - - - 2.3139 - 3.034 0.629 - 829.4 1 2 0 0.0034 15 0 0 0 6.06E+07 4.70E+07 - - - 6.4144 1 221125_WJC_METTL3_EV_vs_WT_F06.12354.12354.2 2.11E-09 16/28 R.VTSVGTGNFSSSVSK.V sp|Q5T3J3|LRIF1_HUMAN 1 1455.7205 1.29 81813 12354 2 1455.72003 728.8675 Ligand-dependent nuclear receptor-interacting factor 1 OS=Homo sapiens OX=9606 GN=LRIF1 PE=1 SV=1 8.72 2282.8 - 2.20E+06 - - - -0.349 - 3.104 0.665 - 865.1 1 2 0 -0.0005 15 0 0 0 6.06E+07 4.70E+07 - - - 6.7373 1 221125_WJC_METTL3_EV_vs_WT_F06.12355.12355.3 0.000123 17/44 R.DNIQGITK[136.11]PAIR[166.11].R sp|P62805|H4_HUMAN 1 1342.7688 0.6 81814 12355 3 1342.76922 448.5969 Histone H4 OS=Homo sapiens OX=9606 GN=H4C1 PE=1 SV=2 8.75 2282.9 - 2.09E+06 - - - 0.3359 - 2.836 0.488 - 541.8 1 2 0 0.0005 12 0 0 0 2.80E+06 4.69E+06 - - - 6.87 1 221125_WJC_METTL3_EV_vs_WT_F06.12356.12356.3 4.71E-06 16/48 K.TFNPGAGLPTDK[136.11]K[136.11].K "sp|P09661|RU2A_HUMAN,tr|H0YMA0|H0YMA0_HUMAN,tr|H0YLR3|H0YLR3_HUMAN" 3 1360.7322 2.35 81815 12356 3 1360.730986 454.5847 U2 small nuclear ribonucleoprotein A' OS=Homo sapiens OX=9606 GN=SNRPA1 PE=1 SV=2 8.26 2283 - 1.34E+06 - - - -0.8664 - 2.665 0.516 - 310.9 1 2 0 -0.0012 13 0 0 0 1.23E+08 5.25E+07 - - - 6.9502 1 221125_WJC_METTL3_EV_vs_WT_F06.12357.12357.3 3.70E-06 18/48 R.LSNRPAFMPSEGK.M "sp|O43707|ACTN4_HUMAN,sp|P35609|ACTN2_HUMAN,tr|A0A494C1A0|A0A494C1A0_HUMAN,tr|F5GXS2|F5GXS2_HUMAN,tr|A0A804HI95|A0A804HI95_HUMAN,tr|H7C144|H7C144_HUMAN" 6 1432.7133 2 81816 12357 3 1432.710989 478.5784 Alpha-actinin-4 OS=Homo sapiens OX=9606 GN=ACTN4 PE=1 SV=2 8.75 2283.1 - 994298 - - - -1.6019 - 2.827 0.495 - 357.7 1 2 0 -0.0023 13 0 0 0 2.25E+07 1.13E+07 - - - 6.8757 0.9928 221125_WJC_METTL3_EV_vs_WT_F06.12361.12361.2 2.74E-07 24-Dec L.EDVTPIPSDSTR[166.11]R[166.11].K "sp|P62263|RS14_HUMAN,tr|A0A2R8Y811|A0A2R8Y811_HUMAN" 2 1491.7432 1.32 81820 12361 2 1491.742253 746.8789 40S ribosomal protein S14 OS=Homo sapiens OX=9606 GN=RPS14 PE=1 SV=3 4.56 2283.6 - 683901 - - - -0.6523 - 2.278 0.516 - 301 1 1 0 -0.001 13 0 0 0 1.59E+07 1.21E+07 - - - 4.9649 0.9999 221125_WJC_METTL3_EV_vs_WT_F06.12363.12363.2 1.36E-09 17/22 R.KAGNFYVPAEPK.L "sp|P18124|RL7_HUMAN,tr|C9JIJ5|C9JIJ5_HUMAN,tr|C9JZ88|C9JZ88_HUMAN,tr|A8MUD9|A8MUD9_HUMAN" 4 1319.6874 1.41 81822 12363 2 1319.687197 660.851 60S ribosomal protein L7 OS=Homo sapiens OX=9606 GN=RPL7 PE=1 SV=1 8.5 2283.8 - 511479 - - - -0.144 - 2.824 0.396 - 849.8 1 2 0 -0.0002 12 0 0 0 4.12E+07 2.91E+07 - - - 4.6974 1 221125_WJC_METTL3_EV_vs_WT_F06.12367.12367.3 4.28E-05 16/44 R.DNIQGITKPAIR.R sp|P62805|H4_HUMAN 1 1324.7463 1.18 81824 12367 3 1324.74531 442.5894 Histone H4 OS=Homo sapiens OX=9606 GN=H4C1 PE=1 SV=2 8.75 2284.3 - 7.72E+06 - - - -0.7466 - 2.575 0.485 - 400.1 1 2 0 -0.001 12 0 0 0 8.29E+09 7.05E+09 - - - 6.5688 1 221125_WJC_METTL3_EV_vs_WT_F06.12368.12368.3 4.37E-05 14/60 R.LAQQMENRPSVQAALK.L "sp|Q9Y3Y2|CHTOP_HUMAN,tr|Q5T7Y7|Q5T7Y7_HUMAN,tr|A0A087X1B7|A0A087X1B7_HUMAN,tr|X6R700|X6R700_HUMAN" 4 1782.9411 1.74 81825 12368 3 1782.93938 595.321 Chromatin target of PRMT1 protein OS=Homo sapiens OX=9606 GN=CHTOP PE=1 SV=2 8.75 2284.3 - 6.13E+06 - - - -0.9378 - 2.882 0.469 - 334.2 1 2 0 -0.0017 16 0 0 0 5.04E+08 2.89E+08 - - - 6.4844 1 221125_WJC_METTL3_EV_vs_WT_F06.12369.12369.2 1.57E-08 16/28 R.APSTYGGGLSVSSSR.F sp|P02533|K1C14_HUMAN 1 1424.6896 13.79 81826 12369 2 1424.688296 713.3521 "Keratin, type I cytoskeletal 14 OS=Homo sapiens OX=9606 GN=KRT14 PE=1 SV=4" 8.79 2284.3 - 5.68E+07 - - - -0.8956 - 2.979 0.605 - 753.3 1 2 0 -0.0013 15 0 0 0 8.61E+08 6.24E+07 - - - 6.1928 0.9991 221125_WJC_METTL3_EV_vs_WT_F06.12371.12371.3 0.00838 14/48 K.ATTVPDFQETR[166.11]PR[166.11].N "sp|Q9NR46|SHLB2_HUMAN,tr|B7ZC38|B7ZC38_HUMAN" 2 1536.7799 1.3 81828 12371 3 1536.77433 513.2673 Endophilin-B2 OS=Homo sapiens OX=9606 GN=SH3GLB2 PE=1 SV=1 6.12 2284.5 - 1.74E+06 - - - -3.6544 - 2.363 0.353 - 227.5 1 2 0 -0.0056 13 0 0 0 8.03E+07 6.20E+07 - - - 4.8056 1 221125_WJC_METTL3_EV_vs_WT_F06.12372.12372.2 7.07E-06 15/26 K.SQGGEPTYNVAVGR[166.11].A "sp|P35080|PROF2_HUMAN,tr|C9JQ45|C9JQ45_HUMAN,tr|G5E9Q6|G5E9Q6_HUMAN,tr|C9J0J7|C9J0J7_HUMAN,tr|C9J712|C9J712_HUMAN" 5 1443.6982 0.93 81829 12372 2 1443.696477 722.8564 Profilin-2 OS=Homo sapiens OX=9606 GN=PFN2 PE=1 SV=3 5.72 2284.6 - 962948 - - - -1.1768 - 3.183 0.638 - 640.5 1 2 0 -0.0017 14 0 0 0 1.15E+08 1.25E+08 - - - 6.6582 1 221125_WJC_METTL3_EV_vs_WT_F06.12373.12373.3 1.44E-07 15/60 K.FLDTSHYSTAGSSSVR.E sp|Q96A65|EXOC4_HUMAN 1 1713.7958 5.73 81830 12373 3 1713.794263 572.2726 Exocyst complex component 4 OS=Homo sapiens OX=9606 GN=EXOC4 PE=1 SV=1 6.74 2284.7 - 928327 - - - -0.9132 - 2.683 0.656 - 185.2 1 2 0 -0.0016 16 0 0 0 7.09E+06 1.24E+06 - - - 8.3857 0.9999 221125_WJC_METTL3_EV_vs_WT_F06.12380.12380.2 3.36E-06 13/26 R.SSFYPDGGDQETAK.T "sp|Q9NYF8|BCLF1_HUMAN,tr|H0YF00|H0YF00_HUMAN,tr|E9PKI6|E9PKI6_HUMAN,tr|A0A1W2PQ43|A0A1W2PQ43_HUMAN,tr|E9PK91|E9PK91_HUMAN,tr|E9PJA7|E9PJA7_HUMAN,tr|E9PK09|E9PK09_HUMAN,tr|E9PQN2|E9PQN2_HUMAN" 8 1500.6369 2.54 81836 12380 2 1500.635518 751.3257 Bcl-2-associated transcription factor 1 OS=Homo sapiens OX=9606 GN=BCLAF1 PE=1 SV=2 4.03 2285.6 - 7.57E+06 - - - -0.8996 - 2.051 0.624 - 321.6 1 2 0 -0.0013 14 0 0 0 1.46E+08 5.78E+07 - - - 5.452 1 221125_WJC_METTL3_EV_vs_WT_F06.12381.12381.3 1.92E-07 Oct-44 R.TNAENEFVTIKK.D sp|P04264|K2C1_HUMAN 1 1392.7249 616.34 81837 12381 3 1392.723043 465.2489 "Keratin, type II cytoskeletal 1 OS=Homo sapiens OX=9606 GN=KRT1 PE=1 SV=6" 5.81 2285.6 - 4.84E+06 - - - -1.3298 - 2.086 0.503 - 126.4 1 2 0 -0.0019 12 0 0 0 2.78E+08 4.51E+05 - - - 6.1854 1 221125_WJC_METTL3_EV_vs_WT_F06.12382.12382.3 0.0093 16/60 R.LAQQMENR[166.11]PSVQAALK[136.11].L "sp|Q9Y3Y2|CHTOP_HUMAN,tr|Q5T7Y7|Q5T7Y7_HUMAN,tr|A0A087X1B7|A0A087X1B7_HUMAN,tr|X6R700|X6R700_HUMAN" 4 1800.9635 1.74 81838 12382 3 1800.960547 601.3285 Chromatin target of PRMT1 protein OS=Homo sapiens OX=9606 GN=CHTOP PE=1 SV=2 8.75 2285.7 - 1.18E+07 - - - -1.6519 - 2.979 0.467 - 433.2 1 2 0 -0.003 16 0 0 0 5.04E+08 2.89E+08 - - - 6.5466 0.9999 221125_WJC_METTL3_EV_vs_WT_F06.12384.12384.2 1.50E-06 22-Oct R.DNIQGITK[136.11]PAIR[166.11].R sp|P62805|H4_HUMAN 1 1342.7688 1.19 81840 12384 2 1342.768434 672.3917 Histone H4 OS=Homo sapiens OX=9606 GN=H4C1 PE=1 SV=2 8.75 2285.7 - 4.05E+06 - - - -0.2495 - 2.203 0.475 - 290.2 1 2 0 -0.0003 12 0 0 0 1.15E+09 9.63E+08 - - - 4.6274 0.9999 221125_WJC_METTL3_EV_vs_WT_F06.12386.12386.2 0.0119 22-Dec R.DNIQGITKPAIR.R sp|P62805|H4_HUMAN 1 1324.7463 1.19 81842 12386 2 1324.745615 663.3804 Histone H4 OS=Homo sapiens OX=9606 GN=H4C1 PE=1 SV=2 8.75 2285.9 - 2.99E+06 - - - -0.5163 - 2.519 0.43 - 508.6 1 2 0 -0.0007 12 0 0 0 1.15E+09 9.63E+08 - - - 4.6476 1 221125_WJC_METTL3_EV_vs_WT_F06.12387.12387.3 1.10E-07 20/56 K.APGAEEYAQQDVLKK.S sp|P09543|CN37_HUMAN 1 1645.8312 0.76 81843 12387 3 1645.832572 549.6177 "2',3'-cyclic-nucleotide 3'-phosphodiesterase OS=Homo sapiens OX=9606 GN=CNP PE=1 SV=2" 4.68 2286.1 - 1.00E+06 - - - 0.8634 - 2.451 0.529 - 254.1 1 2 0 0.0014 15 0 0 0 4.16E+07 5.46E+07 - - - 6.7767 1 221125_WJC_METTL3_EV_vs_WT_F06.12388.12388.2 1.10E-08 17/30 R.LAQQMENRPSVQAALK.L "sp|Q9Y3Y2|CHTOP_HUMAN,tr|Q5T7Y7|Q5T7Y7_HUMAN,tr|A0A087X1B7|A0A087X1B7_HUMAN,tr|X6R700|X6R700_HUMAN" 4 1782.9411 1.85 81844 12388 2 1782.939416 892.4778 Chromatin target of PRMT1 protein OS=Homo sapiens OX=9606 GN=CHTOP PE=1 SV=2 8.75 2286.2 - 691331 - - - -0.9176 - 3.822 0.528 - 593.2 1 2 0 -0.0016 16 0 0 0 2.39E+07 1.29E+07 - - - 6.2366 0.9998 221125_WJC_METTL3_EV_vs_WT_F06.12392.12392.3 2.35E-05 15/48 K.EKEPVVVETVEEK.K sp|Q8N5N7|RM50_HUMAN 1 1513.7876 1.52 81847 12392 3 1513.785799 505.6031 "39S ribosomal protein L50, mitochondrial OS=Homo sapiens OX=9606 GN=MRPL50 PE=1 SV=2" 4.33 2286.7 - 3.85E+06 - - - -1.16 - 2.537 0.458 - 364.6 1 2 1 -0.0018 13 0 0 0 3.62E+07 2.38E+07 - - - 6.1699 0.9999 221125_WJC_METTL3_EV_vs_WT_F06.12393.12393.2 4.10E-06 13/26 R.SSFYPDGGDQETAK[136.11].T "sp|Q9NYF8|BCLF1_HUMAN,tr|H0YF00|H0YF00_HUMAN,tr|E9PKI6|E9PKI6_HUMAN,tr|A0A1W2PQ43|A0A1W2PQ43_HUMAN,tr|E9PK91|E9PK91_HUMAN,tr|E9PJA7|E9PJA7_HUMAN,tr|E9PK09|E9PK09_HUMAN,tr|E9PQN2|E9PQN2_HUMAN" 8 1508.6511 2.52 81848 12393 2 1508.649434 755.3328 Bcl-2-associated transcription factor 1 OS=Homo sapiens OX=9606 GN=BCLAF1 PE=1 SV=2 4.03 2286.7 - 3.76E+06 - - - -1.0831 - 1.769 0.619 - 307.4 1 2 0 -0.0016 14 0 0 0 1.52E+08 6.03E+07 - - - 5.0438 0.9995 221125_WJC_METTL3_EV_vs_WT_F06.12397.12397.3 6.04E-05 14/40 R.NSKIEISELNR.V sp|P04264|K2C1_HUMAN 1 1301.6939 744.63 81852 12397 3 1301.693406 434.9053 "Keratin, type II cytoskeletal 1 OS=Homo sapiens OX=9606 GN=KRT1 PE=1 SV=6" 6.14 2286.9 - 2.59E+06 - - - -0.4018 - 2.679 0.346 - 398.6 1 2 1 -0.0005 11 0 0 0 3.72E+08 4.99E+05 - - - 5.1969 0.9865 221125_WJC_METTL3_EV_vs_WT_F06.12405.12405.2 0.00184 13/18 N.IQGITK[136.11]PAIR[166.11].R sp|P62805|H4_HUMAN 1 1113.6989 1.21 81859 12405 2 1113.697481 557.8567 Histone H4 OS=Homo sapiens OX=9606 GN=H4C1 PE=1 SV=2 11 2287.8 - 3.64E+06 - - - -1.2723 - 2.236 0.413 - 623 1 1 0 -0.0014 10 0 0 0 1.92E+08 1.59E+08 - - - 4.3371 0.9917 221125_WJC_METTL3_EV_vs_WT_F06.12406.12406.2 5.79E-05 16-Nov L.QGITK[136.11]PAIR[166.11].R sp|P62805|H4_HUMAN 1 1000.6148 1.28 81860 12406 2 1000.614089 501.3147 Histone H4 OS=Homo sapiens OX=9606 GN=H4C1 PE=1 SV=2 11 2287.8 - 3.58E+06 - - - -0.7445 - 2.299 0.449 - 524.6 1 1 0 -0.0007 9 0 0 0 2.19E+08 1.70E+08 - - - 4.7655 1 221125_WJC_METTL3_EV_vs_WT_F06.12409.12409.2 1.07E-10 18/30 R.LAQQMENR[166.11]PSVQAALK[136.11].L "sp|Q9Y3Y2|CHTOP_HUMAN,tr|Q5T7Y7|Q5T7Y7_HUMAN,tr|A0A087X1B7|A0A087X1B7_HUMAN,tr|X6R700|X6R700_HUMAN" 4 1800.9635 1.85 81863 12409 2 1800.963647 901.489 Chromatin target of PRMT1 protein OS=Homo sapiens OX=9606 GN=CHTOP PE=1 SV=2 8.75 2288.2 - 807849 - - - 0.0694 - 4.103 0.574 - 675.7 1 2 0 0.0001 16 0 0 0 2.39E+07 1.29E+07 - - - 6.7513 0.9984 221125_WJC_METTL3_EV_vs_WT_F06.12413.12413.2 0.000368 13/20 R.NSKIEISELNR.V sp|P04264|K2C1_HUMAN 1 1301.6939 999 81865 12413 2 1301.69442 651.8542 "Keratin, type II cytoskeletal 1 OS=Homo sapiens OX=9606 GN=KRT1 PE=1 SV=6" 6.14 2288.7 - 1.71E+06 - - - 0.3772 - 2.188 0.469 - 603.2 1 2 1 0.0005 11 0 0 0 7.65E+07 0.00E+00 - - - 4.623 0.9996 221125_WJC_METTL3_EV_vs_WT_F06.12420.12420.3 0.00249 Nov-36 R.RDDAYWPEGK.R sp|Q14151|SAFB2_HUMAN 1 1235.5571 2.54 81872 12420 3 1235.556148 412.8596 Scaffold attachment factor B2 OS=Homo sapiens OX=9606 GN=SAFB2 PE=1 SV=1 4.56 2289.4 - 557954 - - - -0.7713 - 1.615 0.359 - 153.8 1 2 0 -0.001 10 0 0 0 4.81E+06 1.89E+06 - - - 3.9421 0.9936 221125_WJC_METTL3_EV_vs_WT_F06.12422.12422.3 0.0539 Nov-44 R.NQYEALVETNRR.E sp|Q14525|KT33B_HUMAN 1 1491.743 15.95 81873 12422 3 1491.747897 498.2549 "Keratin, type I cuticular Ha3-II OS=Homo sapiens OX=9606 GN=KRT33B PE=1 SV=3" 6.14 2289.7 - 1.05E+06 - - - 3.2801 - 2.194 0.213 - 168.7 1 2 0 0.0049 12 0 0 0 1.25E+07 7.85E+05 - - - 3.0913 0.9665 221125_WJC_METTL3_EV_vs_WT_F06.12425.12425.2 0.0148 18-Aug N.IQGITKPAIR.R sp|P62805|H4_HUMAN 1 1095.6764 1.21 81875 12425 2 1095.675247 548.8455 Histone H4 OS=Homo sapiens OX=9606 GN=H4C1 PE=1 SV=2 11 2289.9 - 1.01E+07 - - - -1.0779 - 1.829 0.321 - 205 1 1 0 -0.0012 10 0 0 0 1.92E+08 1.59E+08 - - - 3.0968 0.9999 221125_WJC_METTL3_EV_vs_WT_F06.12426.12426.2 2.92E-06 26-Dec K.SQGGEPTYNVAVGR.A "sp|P35080|PROF2_HUMAN,tr|C9JQ45|C9JQ45_HUMAN,tr|G5E9Q6|G5E9Q6_HUMAN,tr|C9J0J7|C9J0J7_HUMAN,tr|C9J712|C9J712_HUMAN" 5 1433.6899 0.93 81876 12426 2 1433.68841 717.8522 Profilin-2 OS=Homo sapiens OX=9606 GN=PFN2 PE=1 SV=3 5.72 2290 - 4.08E+06 - - - -1.0435 - 2.901 0.515 - 267.7 1 2 0 -0.0015 14 0 0 0 1.15E+08 1.25E+08 - - - 5.517 0.9768 221125_WJC_METTL3_EV_vs_WT_F06.12430.12430.2 0.133 20-Nov D.NIQGITKPAIR.R sp|P62805|H4_HUMAN 1 1209.7194 1.67 81880 12430 2 1209.718638 605.867 Histone H4 OS=Homo sapiens OX=9606 GN=H4C1 PE=1 SV=2 11 2290.5 - 1.31E+06 - - - -0.5935 - 2.078 0.311 - 401.4 1 1 0 -0.0007 11 0 0 0 2.77E+07 1.66E+07 - - - 3.3164 1 221125_WJC_METTL3_EV_vs_WT_F06.12431.12431.4 0.00127 22/78 K.VVEVLAGHGHLYSR.L sp|P49327|FAS_HUMAN 1 1535.8209 0.58 81881 12431 4 1535.823277 384.9625 Fatty acid synthase OS=Homo sapiens OX=9606 GN=FASN PE=1 SV=3 6.89 2290.6 - 1.21E+06 - - - 1.5731 - 3.862 0.514 - 556.8 1 2 0 0.0024 14 0 0 0 1.52E+07 2.60E+07 - - - 4.1909 0.9771 221125_WJC_METTL3_EV_vs_WT_F06.12435.12435.2 0.00124 16-Jul L.QGITKPAIR.R sp|P62805|H4_HUMAN 1 982.5924 1.28 81883 12435 2 982.59147 492.3035 Histone H4 OS=Homo sapiens OX=9606 GN=H4C1 PE=1 SV=2 11 2291.1 - 1.28E+07 - - - -0.9098 - 1.818 0.361 - 207.2 1 1 0 -0.0009 9 0 0 0 2.19E+08 1.70E+08 - - - 3.4364 0.9999 221125_WJC_METTL3_EV_vs_WT_F06.12437.12437.3 0.000982 Dec-44 R.DNIQGITKPAIR[166.11].R sp|P62805|H4_HUMAN 1 1334.7546 - 81885 12437 3 1334.755645 445.9255 Histone H4 OS=Homo sapiens OX=9606 GN=H4C1 PE=1 SV=2 8.75 2291.2 - 6.84E+06 - - - 0.8061 - 2.06 0.398 - 219.8 1 2 0 0.0011 12 0 0 0 - - - - - 4.9802 1 221125_WJC_METTL3_EV_vs_WT_F06.12438.12438.4 0.000171 19/78 K.VVEVLAGHGHLYSR[166.11].L sp|P49327|FAS_HUMAN 1 1545.8291 0.58 81886 12438 4 1545.826196 387.4646 Fatty acid synthase OS=Homo sapiens OX=9606 GN=FASN PE=1 SV=3 6.89 2291.2 - 3.12E+06 - - - -1.8987 - 3.678 0.514 - 458.4 1 2 0 -0.0029 14 0 0 0 1.52E+07 2.60E+07 - - - 4.173 1 221125_WJC_METTL3_EV_vs_WT_F06.12451.12451.2 1.31E-07 16/34 K.TAENATSGETLEENEAGD.- sp|Q9UQ80|PA2G4_HUMAN 1 1836.7497 - 81897 12451 2 1836.751237 919.3821 Proliferation-associated protein 2G4 OS=Homo sapiens OX=9606 GN=PA2G4 PE=1 SV=3 3.61 2292.9 - 1.54E+06 - - - 0.8232 - 3.09 0.63 - 633.3 1 2 0 0.0015 18 0 0 0 - - - - - 6.4674 0.9977 221125_WJC_METTL3_EV_vs_WT_F06.12453.12453.3 4.47E-08 20/52 R.FSEER[166.11]DPELSTVC[160.03]R[166.11].K sp|Q8NBA8|DTWD2_HUMAN 1 1743.8001 0.16 81899 12453 3 1743.802225 582.274 tRNA-uridine aminocarboxypropyltransferase 2 OS=Homo sapiens OX=9606 GN=DTWD2 PE=1 SV=1 4.41 2293.1 - 1.46E+06 - - - 1.2249 - 3.046 0.223 - 536.5 1 2 1 0.0021 14 0 0 0 4.04E+06 2.45E+07 - - - 3.9857 0.9862 221125_WJC_METTL3_EV_vs_WT_F06.12454.12454.2 2.91E-05 20-Dec D.NIQGITK[136.11]PAIR[166.11].R sp|P62805|H4_HUMAN 1 1227.7418 1.65 81900 12454 2 1227.739736 614.8782 Histone H4 OS=Homo sapiens OX=9606 GN=H4C1 PE=1 SV=2 11 2293.2 - 1.05E+06 - - - -1.7023 - 2.1 0.495 - 515.6 1 1 0 -0.0021 11 0 0 0 2.75E+07 1.66E+07 - - - 4.7035 0.9999 221125_WJC_METTL3_EV_vs_WT_F06.12462.12462.2 0.000295 14/18 R.K[136.11]DSLSVNEFK[136.11].E sp|Q99584|S10AD_HUMAN 1 1181.6263 1.65 81906 12462 2 1181.624775 591.8204 Protein S100-A13 OS=Homo sapiens OX=9606 GN=S100A13 PE=1 SV=1 6.07 2294.1 - 1.17E+06 - - - -1.2931 - 2.658 0.53 - 611.9 1 2 0 -0.0015 10 0 0 0 5.30E+07 3.21E+07 - - - 5.6838 0.9999 221125_WJC_METTL3_EV_vs_WT_F06.12465.12465.3 2.50E-05 Dec-36 R.KDSLSVNEFK.E sp|Q99584|S10AD_HUMAN 1 1165.5979 1.91 81907 12465 3 1165.596558 389.5399 Protein S100-A13 OS=Homo sapiens OX=9606 GN=S100A13 PE=1 SV=1 6.07 2294.4 - 2.94E+06 - - - -1.1539 - 2.435 0.425 - 294.2 1 2 0 -0.0013 10 0 0 0 9.23E+07 4.82E+07 - - - 5.877 1 221125_WJC_METTL3_EV_vs_WT_F06.12467.12467.3 5.73E-05 18/44 K.LLTHNLLSSHVR.G sp|Q9UI30|TR112_HUMAN 1 1388.7888 1.26 81909 12467 3 1388.787894 463.9369 Multifunctional methyltransferase subunit TRM112-like protein OS=Homo sapiens OX=9606 GN=TRMT112 PE=1 SV=1 9.76 2294.7 - 2.07E+06 - - - -0.6754 - 2.758 0.424 - 616.8 1 2 0 -0.0009 12 0 0 0 8.42E+07 6.69E+07 - - - 6.079 0.9997 221125_WJC_METTL3_EV_vs_WT_F06.12468.12468.2 4.84E-06 13/18 R.KESYSVYVYK.V "sp|Q5QNW6|H2B2F_HUMAN,sp|P58876|H2B1D_HUMAN,sp|Q99880|H2B1L_HUMAN,sp|P62807|H2B1C_HUMAN,sp|Q99877|H2B1N_HUMAN,sp|P57053|H2BFS_HUMAN,sp|O60814|H2B1K_HUMAN,sp|Q93079|H2B1H_HUMAN,sp|Q99879|H2B1M_HUMAN,tr|U3KQK0|U3KQK0_HUMAN" 10 1264.634 0.64 81910 12468 2 1264.630836 633.3243 Histone H2B type 2-F OS=Homo sapiens OX=9606 GN=H2BC18 PE=1 SV=3 8.38 2294.8 - 1.51E+06 - - - -2.4655 - 2.647 0.498 - 473.6 1 2 0 -0.0031 10 0 0 0 2.23E+07 3.46E+07 - - - 5.4354 0.9858 221125_WJC_METTL3_EV_vs_WT_F06.12469.12469.2 1.67E-05 20-Dec V.DGGLSIPHSTK[136.11].R "sp|P46777|RL5_HUMAN,tr|A0A2R8Y6J3|A0A2R8Y6J3_HUMAN,tr|Q5T7N0|Q5T7N0_HUMAN" 3 1118.5811 1.36 81911 12469 2 1118.58238 560.2978 60S ribosomal protein L5 OS=Homo sapiens OX=9606 GN=RPL5 PE=1 SV=3 6.74 2295 - 820917 - - - 1.1112 - 2.09 0.441 - 436.3 1 1 0 0.0012 11 0 0 0 2.49E+07 1.83E+07 - - - 4.292 0.9995 221125_WJC_METTL3_EV_vs_WT_F06.12470.12470.3 0.000757 Dec-64 K.YLVVNADEGEPGTC[160.03]K[136.11]DR[166.11].E "sp|P49821|NDUV1_HUMAN,tr|G3V0I5|G3V0I5_HUMAN,tr|B4DE93|B4DE93_HUMAN,tr|E9PJL9|E9PJL9_HUMAN,tr|E9PPR0|E9PPR0_HUMAN,tr|E9PLC6|E9PLC6_HUMAN,tr|E9PMX3|E9PMX3_HUMAN,tr|E9PQP1|E9PQP1_HUMAN,tr|E9PPD6|E9PPD6_HUMAN" 9 1939.9065 1.49 81912 12470 3 1939.905932 647.6428 "NADH dehydrogenase [ubiquinone] flavoprotein 1, mitochondrial OS=Homo sapiens OX=9606 GN=NDUFV1 PE=1 SV=4" 4.32 2295.1 - 610228 - - - -0.2727 - 1.843 0.45 - 124.5 1 2 1 -0.0005 17 0 0 0 7.53E+06 5.05E+06 - - - 5.1015 1 221125_WJC_METTL3_EV_vs_WT_F06.12474.12474.3 2.84E-06 Nov-36 R.KESYSVYVYK.V "sp|Q5QNW6|H2B2F_HUMAN,sp|P58876|H2B1D_HUMAN,sp|Q99880|H2B1L_HUMAN,sp|P62807|H2B1C_HUMAN,sp|Q99877|H2B1N_HUMAN,sp|P57053|H2BFS_HUMAN,sp|O60814|H2B1K_HUMAN,sp|Q93079|H2B1H_HUMAN,sp|Q99879|H2B1M_HUMAN,tr|U3KQK0|U3KQK0_HUMAN" 10 1264.634 0.24 81914 12474 3 1264.632664 422.5519 Histone H2B type 2-F OS=Homo sapiens OX=9606 GN=H2BC18 PE=1 SV=3 8.38 2295.6 - 5.47E+06 - - - -1.0201 - 2.015 0.512 - 206 1 2 0 -0.0013 10 0 0 0 1.36E+08 5.75E+08 - - - 6.294 0.9999 221125_WJC_METTL3_EV_vs_WT_F06.12478.12478.3 0.00134 13/44 R.LLASTLVHSVKK.E "sp|Q9NYF8|BCLF1_HUMAN,tr|E9PKI6|E9PKI6_HUMAN,tr|A0A1W2PQ43|A0A1W2PQ43_HUMAN,tr|E9PK91|E9PK91_HUMAN,tr|E9PJA7|E9PJA7_HUMAN,tr|E9PK09|E9PK09_HUMAN,tr|E9PQN2|E9PQN2_HUMAN" 7 1294.7973 1.63 81918 12478 3 1294.796011 432.6064 Bcl-2-associated transcription factor 1 OS=Homo sapiens OX=9606 GN=BCLAF1 PE=1 SV=2 10 2295.9 - 2.92E+06 - - - -0.9739 - 2.973 0.334 - 221.1 1 2 0 -0.0013 12 0 0 0 2.87E+08 1.76E+08 - - - 5.2836 0.9999 221125_WJC_METTL3_EV_vs_WT_F06.12479.12479.3 3.31E-05 Nov-36 R.K[136.11]DSLSVNEFK[136.11].E sp|Q99584|S10AD_HUMAN 1 1181.6263 1.91 81919 12479 3 1181.630149 394.8827 Protein S100-A13 OS=Homo sapiens OX=9606 GN=S100A13 PE=1 SV=1 6.07 2296 - 2.33E+06 - - - 3.2548 - 2.317 0.497 - 254.4 1 2 0 0.0038 10 0 0 0 9.23E+07 4.82E+07 - - - 6.534 0.9999 221125_WJC_METTL3_EV_vs_WT_F06.12480.12480.2 0.00134 15/22 R.TAAENDFVTLKK.D sp|P35908|K22E_HUMAN 1 1335.7034 999 81920 12480 2 1335.702729 668.859 "Keratin, type II cytoskeletal 2 epidermal OS=Homo sapiens OX=9606 GN=KRT2 PE=1 SV=2" 5.73 2296.1 - 2.30E+06 - - - -0.5256 - 2.541 0.448 - 705.6 1 2 0 -0.0007 12 0 0 0 1.87E+08 0.00E+00 - - - 4.8034 1 221125_WJC_METTL3_EV_vs_WT_F06.12481.12481.2 3.28E-06 15/18 R.KDSLSVNEFK.E sp|Q99584|S10AD_HUMAN 1 1165.5979 1.65 81921 12481 2 1165.595735 583.8062 Protein S100-A13 OS=Homo sapiens OX=9606 GN=S100A13 PE=1 SV=1 6.07 2296.2 - 2.08E+06 - - - -1.86 - 3.003 0.567 - 719 1 2 0 -0.0022 10 0 0 0 5.30E+07 3.21E+07 - - - 6.2975 0.9999 221125_WJC_METTL3_EV_vs_WT_F06.12486.12486.3 0.00859 17/44 R.LLASTLVHSVK[136.11]K[136.11].E "sp|Q9NYF8|BCLF1_HUMAN,tr|E9PKI6|E9PKI6_HUMAN,tr|A0A1W2PQ43|A0A1W2PQ43_HUMAN,tr|E9PK91|E9PK91_HUMAN,tr|E9PJA7|E9PJA7_HUMAN,tr|E9PK09|E9PK09_HUMAN,tr|E9PQN2|E9PQN2_HUMAN" 7 1310.8257 1.64 81924 12486 3 1310.825592 437.9492 Bcl-2-associated transcription factor 1 OS=Homo sapiens OX=9606 GN=BCLAF1 PE=1 SV=2 10 2296.8 - 6.25E+06 - - - -0.061 - 2.773 0.351 - 454.5 1 2 0 -0.0001 12 0 0 0 2.88E+08 1.76E+08 - - - 5.2804 1 221125_WJC_METTL3_EV_vs_WT_F06.12489.12489.2 3.78E-08 22-Dec R.SGYGFNEPEQSR[166.11].F sp|Q5BKZ1|ZN326_HUMAN 1 1379.5981 1.4 81927 12489 2 1379.596798 690.8063 DBIRD complex subunit ZNF326 OS=Homo sapiens OX=9606 GN=ZNF326 PE=1 SV=2 4.53 2297.1 - 1.32E+06 - - - -0.964 - 2.461 0.618 - 400.7 1 2 0 -0.0013 12 0 0 0 8.05E+07 5.75E+07 - - - 5.9747 1 221125_WJC_METTL3_EV_vs_WT_F06.12493.12493.3 4.49E-08 15/44 R.TAAENDFVTLKK.D sp|P35908|K22E_HUMAN 1 1335.7034 120.08 81929 12493 3 1335.701539 446.2418 "Keratin, type II cytoskeletal 2 epidermal OS=Homo sapiens OX=9606 GN=KRT2 PE=1 SV=2" 5.73 2297.6 - 4.32E+07 - - - -1.4165 - 2.855 0.516 - 310.6 1 2 0 -0.0019 12 0 0 0 1.15E+09 9.60E+06 - - - 7.2002 1 221125_WJC_METTL3_EV_vs_WT_F06.12494.12494.3 1.68E-05 15/44 K.LLTHNLLSSHVR[166.11].G sp|Q9UI30|TR112_HUMAN 1 1398.7971 1.26 81930 12494 3 1398.796653 467.273 Multifunctional methyltransferase subunit TRM112-like protein OS=Homo sapiens OX=9606 GN=TRMT112 PE=1 SV=1 9.76 2297.6 - 4.18E+06 - - - -0.321 - 2.498 0.477 - 299.1 1 2 0 -0.0004 12 0 0 0 8.42E+07 6.69E+07 - - - 6.3956 0.9999 221125_WJC_METTL3_EV_vs_WT_F06.12499.12499.2 0.0101 15/22 R.LLASTLVHSVKK.E "sp|Q9NYF8|BCLF1_HUMAN,tr|E9PKI6|E9PKI6_HUMAN,tr|A0A1W2PQ43|A0A1W2PQ43_HUMAN,tr|E9PK91|E9PK91_HUMAN,tr|E9PJA7|E9PJA7_HUMAN,tr|E9PK09|E9PK09_HUMAN,tr|E9PQN2|E9PQN2_HUMAN" 7 1294.7973 1.95 81935 12499 2 1294.796391 648.4059 Bcl-2-associated transcription factor 1 OS=Homo sapiens OX=9606 GN=BCLAF1 PE=1 SV=2 10 2298.2 - 840491 - - - -0.6804 - 2.725 0.407 - 718.5 1 2 0 -0.0009 12 0 0 0 2.86E+07 1.47E+07 - - - 4.6845 0.9969 221125_WJC_METTL3_EV_vs_WT_F06.12500.12500.3 0.0406 Oct-36 K.DILILSSHKK.A sp|Q14966|ZN638_HUMAN 1 1152.6867 0.63 81936 12500 3 1152.684876 385.2362 Zinc finger protein 638 OS=Homo sapiens OX=9606 GN=ZNF638 PE=1 SV=2 8.6 2298.3 - 609253 - - - -1.5468 - 1.577 0.256 - 81.9 1 2 0 -0.0018 10 0 0 0 6.95E+06 1.10E+07 - - - 2.724 1 221125_WJC_METTL3_EV_vs_WT_F06.12503.12503.2 1.68E-07 22-Dec R.SGYGFNEPEQSR.F sp|Q5BKZ1|ZN326_HUMAN 1 1369.5899 1.4 81937 12503 2 1369.590244 685.8022 DBIRD complex subunit ZNF326 OS=Homo sapiens OX=9606 GN=ZNF326 PE=1 SV=2 4.53 2298.7 - 1.95E+06 - - - 0.2818 - 2.44 0.634 - 393.6 1 2 0 0.0004 12 0 0 0 8.05E+07 5.75E+07 - - - 6.0706 0.9999 221125_WJC_METTL3_EV_vs_WT_F06.12505.12505.2 1.46E-05 13/32 K.VTAQGPGLEPSGNIANK[136.11].T "sp|P21333|FLNA_HUMAN,tr|A0A7P0NMY4|A0A7P0NMY4_HUMAN,tr|Q60FE5|Q60FE5_HUMAN,tr|A0A7I2V3E6|A0A7I2V3E6_HUMAN,tr|A0A087WWY3|A0A087WWY3_HUMAN,tr|F8WE98|F8WE98_HUMAN" 6 1659.8671 1.25 81939 12505 2 1659.866691 830.9409 Filamin-A OS=Homo sapiens OX=9606 GN=FLNA PE=1 SV=4 5.97 2299 - 1.30E+06 - - - -0.2759 - 3.133 0.459 - 346.1 1 2 0 -0.0005 17 0 0 0 5.24E+07 4.19E+07 - - - 5.2387 0.9997 221125_WJC_METTL3_EV_vs_WT_F06.12506.12506.2 0.00642 20-Oct R.TEEGPTLSYGR.D "sp|P43243|MATR3_HUMAN,tr|A8MXP9|A8MXP9_HUMAN,tr|D6R991|D6R991_HUMAN,tr|A0A0R4J2E8|A0A0R4J2E8_HUMAN,tr|D6REM6|D6REM6_HUMAN" 5 1208.5673 0.86 81940 12506 2 1208.564954 605.2909 Matrin-3 OS=Homo sapiens OX=9606 GN=MATR3 PE=1 SV=2 4.53 2299.1 - 1.00E+06 - - - -1.9668 - 2.147 0.504 - 416.8 1 2 0 -0.0024 11 0 0 0 3.76E+07 4.36E+07 - - - 4.8298 0.9942 221125_WJC_METTL3_EV_vs_WT_F06.12507.12507.2 0.0111 14/22 F.SSGSAGIINYQR.R sp|P04264|K2C1_HUMAN 1 1251.6208 999 81941 12507 2 1251.621072 626.8177 "Keratin, type II cytoskeletal 1 OS=Homo sapiens OX=9606 GN=KRT1 PE=1 SV=6" 8.46 2299.2 - 945752 - - - 0.2461 - 2.889 0.474 - 790.3 1 1 0 0.0003 12 0 0 0 2.20E+07 0.00E+00 - - - 5.3333 0.9992 221125_WJC_METTL3_EV_vs_WT_F06.12508.12508.2 0.00526 20-Nov R.TEEGPTLSYGR[166.11].D "sp|P43243|MATR3_HUMAN,tr|A8MXP9|A8MXP9_HUMAN,tr|D6R991|D6R991_HUMAN,tr|A0A0R4J2E8|A0A0R4J2E8_HUMAN,tr|D6REM6|D6REM6_HUMAN" 5 1218.5756 1.11 81942 12508 2 1218.572198 610.2951 Matrin-3 OS=Homo sapiens OX=9606 GN=MATR3 PE=1 SV=2 4.53 2299.4 - 915092 - - - -2.7926 - 2.019 0.423 - 509.5 1 2 0 -0.0034 11 0 0 0 2.59E+07 2.34E+07 - - - 4.0649 0.9992 221125_WJC_METTL3_EV_vs_WT_F06.12514.12514.3 0.00478 Aug-52 K.GAVDGGLSIPHSTK[136.11].R "sp|P46777|RL5_HUMAN,tr|A0A2R8Y6J3|A0A2R8Y6J3_HUMAN,tr|Q5T7N0|Q5T7N0_HUMAN" 3 1345.7081 1.11 81946 12514 3 1345.706587 449.5767 60S ribosomal protein L5 OS=Homo sapiens OX=9606 GN=RPL5 PE=1 SV=3 6.74 2300.1 - 2.26E+07 - - - -1.1459 - 1.607 0.334 - 70.5 1 2 0 -0.0015 14 0 0 0 5.85E+08 5.26E+08 - - - 3.524 1 221125_WJC_METTL3_EV_vs_WT_F06.12517.12517.2 1.13E-09 19/32 K.VTAQGPGLEPSGNIANK.T "sp|P21333|FLNA_HUMAN,tr|A0A7P0NMY4|A0A7P0NMY4_HUMAN,tr|Q60FE5|Q60FE5_HUMAN,tr|A0A7I2V3E6|A0A7I2V3E6_HUMAN,tr|A0A087WWY3|A0A087WWY3_HUMAN,tr|F8WE98|F8WE98_HUMAN" 6 1651.8529 1.25 81949 12517 2 1651.852706 826.9338 Filamin-A OS=Homo sapiens OX=9606 GN=FLNA PE=1 SV=4 5.97 2300.4 - 2.84E+06 - - - -0.1471 - 3.551 0.609 - 819.4 1 2 0 -0.0002 17 0 0 0 5.24E+07 4.19E+07 - - - 6.6545 0.9943 221125_WJC_METTL3_EV_vs_WT_F06.12524.12524.2 4.98E-07 18-Nov A.AENDFVTLKK.D sp|P35908|K22E_HUMAN 1 1163.6186 999 81954 12524 2 1163.618097 582.8166 "Keratin, type II cytoskeletal 2 epidermal OS=Homo sapiens OX=9606 GN=KRT2 PE=1 SV=2" 6.11 2301.2 - 2.94E+06 - - - -0.4658 - 2.282 0.545 - 471.7 1 1 0 -0.0005 10 0 0 0 2.81E+07 0.00E+00 - - - 5.3692 0.9996 221125_WJC_METTL3_EV_vs_WT_F06.12526.12526.3 0.000747 Dec-64 K.VTAQGPGLEPSGNIANK.T "sp|P21333|FLNA_HUMAN,tr|A0A7P0NMY4|A0A7P0NMY4_HUMAN,tr|Q60FE5|Q60FE5_HUMAN,tr|A0A7I2V3E6|A0A7I2V3E6_HUMAN,tr|A0A087WWY3|A0A087WWY3_HUMAN,tr|F8WE98|F8WE98_HUMAN" 6 1651.8529 1.11 81956 12526 3 1651.855258 551.6249 Filamin-A OS=Homo sapiens OX=9606 GN=FLNA PE=1 SV=4 5.97 2301.3 - 2.51E+06 - - - 1.3978 - 2.168 0.344 - 184.1 1 2 0 0.0023 17 0 0 0 2.79E+07 2.52E+07 - - - 4.3295 1 221125_WJC_METTL3_EV_vs_WT_F06.12527.12527.2 8.59E-06 16/22 R.LLASTLVHSVK[136.11]K[136.11].E "sp|Q9NYF8|BCLF1_HUMAN,tr|E9PKI6|E9PKI6_HUMAN,tr|A0A1W2PQ43|A0A1W2PQ43_HUMAN,tr|E9PK91|E9PK91_HUMAN,tr|E9PJA7|E9PJA7_HUMAN,tr|E9PK09|E9PK09_HUMAN,tr|E9PQN2|E9PQN2_HUMAN" 7 1310.8257 1.95 81957 12527 2 1310.825273 656.4201 Bcl-2-associated transcription factor 1 OS=Homo sapiens OX=9606 GN=BCLAF1 PE=1 SV=2 10 2301.5 - 1.60E+06 - - - -0.3044 - 3.07 0.568 - 768.9 1 2 0 -0.0004 12 0 0 0 2.86E+07 1.47E+07 - - - 6.1874 1 221125_WJC_METTL3_EV_vs_WT_F06.12529.12529.4 2.39E-07 15/72 K.LISSDGHEFIVK[136.11]R[166.11].E "sp|Q15369|ELOC_HUMAN,tr|R4GMY8|R4GMY8_HUMAN,tr|E5RHG8|E5RHG8_HUMAN" 3 1517.8321 0.001 81959 12529 4 1517.829164 380.4653 Elongin-C OS=Homo sapiens OX=9606 GN=ELOC PE=1 SV=1 6.75 2301.6 - 1.10E+06 - - - -1.9324 - 2.829 0.535 - 255.9 1 2 0 -0.0029 13 0 0 0 0.00E+00 9.90E+06 - - - 4.2674 1 221125_WJC_METTL3_EV_vs_WT_F06.12531.12531.2 4.03E-10 14/24 K.QMENTALQNEVQR[166.11].L "sp|Q15643|TRIPB_HUMAN,tr|H0YJ97|H0YJ97_HUMAN" 2 1569.7445 1.56 81961 12531 2 1569.742728 785.8795 Thyroid receptor-interacting protein 11 OS=Homo sapiens OX=9606 GN=TRIP11 PE=1 SV=3 4.53 2301.9 - 1.07E+06 - - - -1.1123 - 3.112 0.549 - 990 1 2 0 -0.0017 13 0 0 0 2.09E+07 1.34E+07 - - - 6.0091 0.9999 221125_WJC_METTL3_EV_vs_WT_F06.12532.12532.3 0.00115 13/44 R.VNVPVIGGHAGK.T "sp|P40926|MDHM_HUMAN,tr|G3XAL0|G3XAL0_HUMAN" 2 1146.6509 1.64 81962 12532 3 1146.65112 383.2243 "Malate dehydrogenase, mitochondrial OS=Homo sapiens OX=9606 GN=MDH2 PE=1 SV=3" 8.73 2302 - 721093 - - - 0.1552 - 2.157 0.42 - 203.8 1 2 0 0.0002 12 0 0 0 9.34E+06 5.71E+06 - - - 5.3533 0.9992 221125_WJC_METTL3_EV_vs_WT_F06.12536.12536.3 0.00103 15/48 R.NIAVGKDPLEGQR.H "sp|O00170|AIP_HUMAN,tr|A0A804HKP8|A0A804HKP8_HUMAN,tr|A0A804HKK3|A0A804HKK3_HUMAN,tr|A0A804HKL7|A0A804HKL7_HUMAN,tr|V9GYQ3|V9GYQ3_HUMAN,tr|A0A804HKH9|A0A804HKH9_HUMAN,tr|A0A804HIX8|A0A804HIX8_HUMAN,tr|A0A804HJ38|A0A804HJ38_HUMAN" 8 1395.747 5.3 81964 12536 3 1395.747139 466.2563 AH receptor-interacting protein OS=Homo sapiens OX=9606 GN=AIP PE=1 SV=2 6.07 2302.6 - 2.94E+06 - - - 0.0802 - 2.234 0.355 - 285.8 1 2 1 0.0001 13 0 0 0 5.02E+07 9.46E+06 - - - 4.6772 0.9999 221125_WJC_METTL3_EV_vs_WT_F06.12537.12537.3 7.22E-06 17/48 K.TSLTVADKIEDQK.K "sp|P52732|KIF11_HUMAN,tr|A0A7I2V3A9|A0A7I2V3A9_HUMAN" 2 1446.7566 5.81 81965 12537 3 1446.755683 483.2595 Kinesin-like protein KIF11 OS=Homo sapiens OX=9606 GN=KIF11 PE=1 SV=2 4.56 2302.6 - 3.41E+06 - - - -0.6262 - 3.06 0.523 - 337.2 1 2 1 -0.0009 13 0 0 0 4.30E+07 7.40E+06 - - - 7.403 0.9975 221125_WJC_METTL3_EV_vs_WT_F06.12539.12539.3 0.00514 Nov-36 K.QK[136.11]VENLFNEK[136.11].C "sp|P78347|GTF2I_HUMAN,tr|A0A494C1K3|A0A494C1K3_HUMAN" 2 1263.6794 1.62 81967 12539 3 1263.677875 422.2337 General transcription factor II-I OS=Homo sapiens OX=9606 GN=GTF2I PE=1 SV=2 6.14 2302.8 - 2.25E+06 - - - -1.2076 - 2.134 0.275 - 197.9 1 2 1 -0.0015 10 0 0 0 7.83E+08 4.85E+08 - - - 3.8192 0.9994 221125_WJC_METTL3_EV_vs_WT_F06.12540.12540.3 0.00944 17/36 R.LQILHIHTAR[166.11].M "sp|P46459|NSF_HUMAN,tr|I3L0N3|I3L0N3_HUMAN" 2 1210.7174 4.9 81968 12540 3 1210.716892 404.5797 Vesicle-fusing ATPase OS=Homo sapiens OX=9606 GN=NSF PE=1 SV=3 9.76 2302.9 - 1.95E+06 - - - -0.4155 - 2.619 0.213 - 413.5 1 2 0 -0.0005 10 0 0 0 7.04E+07 1.44E+07 - - - 3.7264 0.9537 221125_WJC_METTL3_EV_vs_WT_F06.12541.12541.3 0.00849 14/40 L.LASTLVHSVKK.E "sp|Q9NYF8|BCLF1_HUMAN,tr|E9PKI6|E9PKI6_HUMAN,tr|A0A1W2PQ43|A0A1W2PQ43_HUMAN,tr|E9PK91|E9PK91_HUMAN,tr|E9PJA7|E9PJA7_HUMAN,tr|E9PK09|E9PK09_HUMAN,tr|E9PQN2|E9PQN2_HUMAN" 7 1181.7132 1.42 81969 12541 3 1181.711437 394.9117 Bcl-2-associated transcription factor 1 OS=Homo sapiens OX=9606 GN=BCLAF1 PE=1 SV=2 10 2303 - 1.64E+06 - - - -1.4987 - 2.14 0.304 - 145.8 1 1 0 -0.0018 11 0 0 0 1.11E+07 7.81E+06 - - - 4.0901 0.9999 221125_WJC_METTL3_EV_vs_WT_F06.12542.12542.3 0.0182 14/36 R.LQILHIHTAR.M "sp|P46459|NSF_HUMAN,tr|I3L0N3|I3L0N3_HUMAN" 2 1200.7091 5.03 81970 12542 3 1200.708438 401.2437 Vesicle-fusing ATPase OS=Homo sapiens OX=9606 GN=NSF PE=1 SV=3 9.76 2303.1 - 1.61E+06 - - - -0.5722 - 2.458 0.352 - 284.7 1 2 0 -0.0007 10 0 0 0 7.42E+07 1.47E+07 - - - 5.0908 0.9685 221125_WJC_METTL3_EV_vs_WT_F06.12543.12543.3 0.592 Sep-52 K.ATIAGGGVIPHIHK[136.11].S "sp|P0C0S5|H2AZ_HUMAN,sp|Q71UI9|H2AV_HUMAN" 2 1377.7972 1.19 81971 12543 3 1377.795113 460.273 Histone H2A.Z OS=Homo sapiens OX=9606 GN=H2AZ1 PE=1 SV=2 8.81 2303.2 - 1.45E+06 - - - -1.5285 - 1.855 0.099 - 91.5 1 2 0 -0.0021 14 0 0 0 1.00E+07 8.44E+06 - - - 1.2852 0.9996 221125_WJC_METTL3_EV_vs_WT_F06.12544.12544.3 0.00627 13/52 K.ATIAGGGVIPHIHK.S "sp|P0C0S5|H2AZ_HUMAN,sp|Q71UI9|H2AV_HUMAN" 2 1369.783 1.15 81972 12544 3 1369.78127 457.6016 Histone H2A.Z OS=Homo sapiens OX=9606 GN=H2AZ1 PE=1 SV=2 8.81 2303.3 - 1.32E+06 - - - -1.2768 - 2.429 0.289 - 100.5 1 2 0 -0.0017 14 0 0 0 8.55E+06 7.43E+06 - - - 4.1201 0.9926 221125_WJC_METTL3_EV_vs_WT_F06.12545.12545.3 0.00955 Nov-48 K.TYK[136.11]GSEEELADIK[136.11].Q sp|Q8WXX5|DNJC9_HUMAN 1 1497.7534 5.95 81973 12545 3 1497.753336 500.2584 DnaJ homolog subfamily C member 9 OS=Homo sapiens OX=9606 GN=DNAJC9 PE=1 SV=1 4.41 2303.4 - 1.32E+06 - - - -0.012 - 1.962 0.234 - 113.3 1 2 1 0 13 0 0 0 5.33E+07 8.96E+06 - - - 2.9762 0.9999 221125_WJC_METTL3_EV_vs_WT_F06.12548.12548.3 0.00352 13/44 R.VNVPVIGGHAGK[136.11].T "sp|P40926|MDHM_HUMAN,tr|G3XAL0|G3XAL0_HUMAN" 2 1154.6651 1.9 81976 12548 3 1154.664845 385.8957 "Malate dehydrogenase, mitochondrial OS=Homo sapiens OX=9606 GN=MDH2 PE=1 SV=3" 8.73 2303.8 - 480134 - - - -0.2572 - 2.151 0.373 - 143.4 1 2 0 -0.0003 12 0 0 0 1.16E+07 6.12E+06 - - - 4.8216 0.9994 221125_WJC_METTL3_EV_vs_WT_F06.12552.12552.3 0.00459 13/36 K.QKVENLFNEK.C "sp|P78347|GTF2I_HUMAN,tr|A0A494C1K3|A0A494C1K3_HUMAN" 2 1247.651 1.61 81979 12552 3 1247.649794 416.8909 General transcription factor II-I OS=Homo sapiens OX=9606 GN=GTF2I PE=1 SV=2 6.14 2304.2 - 6.31E+06 - - - -0.9674 - 2.335 0.347 - 254.6 1 2 1 -0.0012 10 0 0 0 7.81E+08 4.85E+08 - - - 4.8849 1 221125_WJC_METTL3_EV_vs_WT_F06.12553.12553.3 1.16E-05 21/64 K.VYVGNLGNNGNK[136.11]TELER[166.11].A "sp|P84103|SRSF3_HUMAN,tr|A0A087X2D0|A0A087X2D0_HUMAN" 2 1893.9664 1.53 81980 12553 3 1893.966233 632.3294 Serine\arginine-rich splicing factor 3 OS=Homo sapiens OX=9606 GN=SRSF3 PE=1 SV=1 6.11 2304.3 - 3.10E+06 - - - -0.0665 - 3.5 0.591 - 487.7 1 2 1 -0.0001 17 0 0 0 1.16E+08 7.55E+07 - - - 8.2939 1 221125_WJC_METTL3_EV_vs_WT_F06.12557.12557.3 1.37E-09 20/60 R.LPPGFSASSTVEKPSK.V "sp|O75694|NU155_HUMAN,tr|E9PF10|E9PF10_HUMAN" 2 1630.8566 1.68 81984 12557 3 1630.858041 544.6262 Nuclear pore complex protein Nup155 OS=Homo sapiens OX=9606 GN=NUP155 PE=1 SV=1 8.59 2304.7 - 1.45E+06 - - - 0.8609 - 3.42 0.565 - 580.4 1 2 0 0.0014 16 0 0 0 1.96E+07 1.17E+07 - - - 7.9939 1 221125_WJC_METTL3_EV_vs_WT_F06.12558.12558.3 3.57E-10 19/68 R.LIITSAEASPAEC[160.03]C[160.03]QHAK.L "sp|Q14C86|GAPD1_HUMAN,tr|B4DGD8|B4DGD8_HUMAN,tr|F8W9S7|F8W9S7_HUMAN,tr|C9IZ08|C9IZ08_HUMAN,tr|C9IZX9|C9IZX9_HUMAN,tr|B0QZ65|B0QZ65_HUMAN" 6 1984.9346 1.5 81985 12558 3 1984.936317 662.6522 GTPase-activating protein and VPS9 domain-containing protein 1 OS=Homo sapiens OX=9606 GN=GAPVD1 PE=1 SV=2 5.4 2304.8 - 1.12E+06 - - - 0.8413 - 3.167 0.619 - 272.5 1 2 0 0.0017 18 0 0 0 1.34E+07 8.95E+06 - - - 8.3113 0.9999 221125_WJC_METTL3_EV_vs_WT_F06.12559.12559.3 9.16E-05 Dec-48 K.QVKPLPAPLDGQR.K "sp|Q8WWY3|PRP31_HUMAN,tr|E7EVX8|E7EVX8_HUMAN" 2 1417.8041 -1 81986 12559 3 1417.806198 473.6087 U4\U6 small nuclear ribonucleoprotein Prp31 OS=Homo sapiens OX=9606 GN=PRPF31 PE=1 SV=2 8.75 2304.9 - 997402 - - - 1.4459 - 2.189 0.435 - 261.3 1 2 0 0.0021 13 0 0 0 0.00E+00 0.00E+00 - - - 5.5134 1 221125_WJC_METTL3_EV_vs_WT_F06.12563.12563.2 2.53E-08 21/34 R.LLEGEDAHLSSQQASGQS.Y sp|P08779|K1C16_HUMAN 1 1855.8548 - 81990 12563 2 1855.855809 928.9347 "Keratin, type I cytoskeletal 16 OS=Homo sapiens OX=9606 GN=KRT16 PE=1 SV=4" 4.13 2305.4 - 823688 - - - 0.5442 - 3.594 0.647 - 1049.4 1 1 0 0.001 18 0 0 0 - - - - - 6.9646 1 221125_WJC_METTL3_EV_vs_WT_F06.12568.12568.2 1.03E-12 16/34 R.GDSEPTPGC[160.03]SGLGPGGVR[166.11].G "sp|Q8WW01|SEN15_HUMAN,tr|E9PPN1|E9PPN1_HUMAN,tr|F2Z3M0|F2Z3M0_HUMAN,tr|A0A2U3TZM3|A0A2U3TZM3_HUMAN,tr|A0A2R8YG40|A0A2R8YG40_HUMAN,tr|H0YCV5|H0YCV5_HUMAN,tr|A0A2R8Y5L0|A0A2R8Y5L0_HUMAN,tr|A0A2R8YDU8|A0A2R8YDU8_HUMAN,tr|A0A2R8YHG0|A0A2R8YHG0_HUMAN,tr|A0A2R8Y6M5|A0A2R8Y6M5_HUMAN,tr|A0A2R8Y6B3|A0A2R8Y6B3_HUMAN,tr|A0A2R8YEM0|A0A2R8YEM0_HUMAN,tr|A0A2R8Y6A4|A0A2R8Y6A4_HUMAN" 13 1708.7714 1.13 81995 12568 2 1708.769845 855.393 tRNA-splicing endonuclease subunit Sen15 OS=Homo sapiens OX=9606 GN=TSEN15 PE=1 SV=1 4.37 2306.1 - 261309 - - - -0.9205 - 2.932 0.748 - 481.5 1 2 0 -0.0016 18 0 0 0 1.27E+07 1.13E+07 - - - 7.2099 1 221125_WJC_METTL3_EV_vs_WT_F06.12572.12572.3 6.71E-10 19/64 K.VYVGNLGNNGNKTELER.A "sp|P84103|SRSF3_HUMAN,tr|A0A087X2D0|A0A087X2D0_HUMAN" 2 1875.9439 1.53 81997 12572 3 1875.944051 626.3219 Serine\arginine-rich splicing factor 3 OS=Homo sapiens OX=9606 GN=SRSF3 PE=1 SV=1 6.11 2306.5 - 1.28E+07 - - - 0.0864 - 3.56 0.624 - 428 1 2 1 0.0002 17 0 0 0 1.16E+08 7.55E+07 - - - 8.7047 0.9992 221125_WJC_METTL3_EV_vs_WT_F06.12576.12576.3 4.41E-05 13/52 R.ARPATDSFDDYPPR.R "sp|P23588|IF4B_HUMAN,tr|E7EX17|E7EX17_HUMAN,tr|F8VSC7|F8VSC7_HUMAN,tr|F8W0K0|F8W0K0_HUMAN,tr|F8VP89|F8VP89_HUMAN" 5 1606.7376 -1 82001 12576 3 1606.729092 536.5865 Eukaryotic translation initiation factor 4B OS=Homo sapiens OX=9606 GN=EIF4B PE=1 SV=2 4.43 2306.7 - 3.03E+06 - - - -5.2859 - 2.341 0.479 - 206.1 1 2 0 -0.0085 14 0 0 0 0.00E+00 0.00E+00 - - - 6.1385 1 221125_WJC_METTL3_EV_vs_WT_F06.12582.12582.3 6.07E-07 14/56 R.YYDSR[166.11]PGGYGYGYGR[166.11].S sp|P98179|RBM3_HUMAN 1 1749.765 0.91 82007 12582 3 1749.763053 584.2623 RNA-binding protein 3 OS=Homo sapiens OX=9606 GN=RBM3 PE=1 SV=1 8.38 2307.1 - 1.51E+06 - - - -1.1264 - 2.225 0.595 - 141 1 2 0 -0.002 15 0 0 0 1.09E+07 1.19E+07 - - - 7.26 0.9998 221125_WJC_METTL3_EV_vs_WT_F06.12583.12583.3 3.17E-05 13/44 R.R[166.11]VEGIQYEDISK[136.11].L sp|O60870|KIN17_HUMAN 1 1453.7532 0.91 82008 12583 3 1453.755567 485.5917 DNA\RNA-binding protein KIN17 OS=Homo sapiens OX=9606 GN=KIN PE=1 SV=2 4.68 2307.2 - 1.26E+06 - - - 1.6433 - 2.156 0.396 - 279.3 1 2 0 0.0024 12 0 0 0 1.55E+07 1.71E+07 - - - 5.0838 1 221125_WJC_METTL3_EV_vs_WT_F06.12584.12584.3 1.86E-06 16/56 R.YYDSRPGGYGYGYGR.S sp|P98179|RBM3_HUMAN 1 1729.7485 0.91 82009 12584 3 1729.749098 577.5901 RNA-binding protein 3 OS=Homo sapiens OX=9606 GN=RBM3 PE=1 SV=1 8.38 2307.3 - 1.25E+06 - - - 0.355 - 2.745 0.63 - 182 1 2 0 0.0006 15 0 0 0 1.09E+07 1.19E+07 - - - 8.1986 1 221125_WJC_METTL3_EV_vs_WT_F06.12585.12585.2 8.87E-06 19/34 L.YQGAGGPGPGGFGAQGPK.G "sp|P0DMV8|HS71A_HUMAN,sp|P0DMV9|HS71B_HUMAN,tr|V9GZ37|V9GZ37_HUMAN,tr|A0A0G2JIW1|A0A0G2JIW1_HUMAN" 4 1601.7587 0.17 82010 12585 2 1601.757853 801.8866 Heat shock 70 kDa protein 1A OS=Homo sapiens OX=9606 GN=HSPA1A PE=1 SV=1 8.59 2307.4 - 844830 - - - -0.5001 - 3.376 0.618 - 1025.4 1 1 0 -0.0008 18 0 0 0 1.99E+07 1.19E+08 - - - 6.5966 0.9995 221125_WJC_METTL3_EV_vs_WT_F06.12587.12587.3 0.000935 19/60 K.RPWLSATPSSGASAAR.Q sp|Q9BTC0|DIDO1_HUMAN 1 1613.8274 0.29 82012 12587 3 1613.831998 538.9497 Death-inducer obliterator 1 OS=Homo sapiens OX=9606 GN=DIDO1 PE=1 SV=5 12 2307.7 - 784733 - - - 2.8473 - 2.518 0.36 - 234.7 1 2 0 0.0046 16 0 0 0 5.26E+06 1.81E+07 - - - 4.9219 0.9996 221125_WJC_METTL3_EV_vs_WT_F06.12588.12588.3 0.00777 Aug-44 K.GGGHVAQIYAIR.Q "sp|P62249|RS16_HUMAN,tr|M0R210|M0R210_HUMAN,tr|M0R3H0|M0R3H0_HUMAN,tr|M0QX76|M0QX76_HUMAN,tr|M0R1M5|M0R1M5_HUMAN" 5 1240.6677 0.18 82013 12588 3 1240.668249 414.5632 40S ribosomal protein S16 OS=Homo sapiens OX=9606 GN=RPS16 PE=1 SV=2 8.75 2307.8 - 748135 - - - 0.4788 - 1.927 0.331 - 76.1 1 2 0 0.0006 12 0 0 0 1.41E+07 8.03E+07 - - - 4.0484 1 221125_WJC_METTL3_EV_vs_WT_F06.12590.12590.2 1.12E-10 16/32 K.VYVGNLGNNGNKTELER.A "sp|P84103|SRSF3_HUMAN,tr|A0A087X2D0|A0A087X2D0_HUMAN" 2 1875.9439 1.86 82015 12590 2 1875.94629 938.9792 Serine\arginine-rich splicing factor 3 OS=Homo sapiens OX=9606 GN=SRSF3 PE=1 SV=1 6.11 2308.1 - 402261 - - - 1.2799 - 3.24 0.674 - 654.7 1 2 1 0.0024 17 0 0 0 5.94E+06 3.20E+06 - - - 6.9086 0.9964 221125_WJC_METTL3_EV_vs_WT_F06.12594.12594.2 0.0745 18-Oct R.TKYETELNLR.M sp|P02533|K1C14_HUMAN 1 1265.6616 999 82017 12594 2 1265.661109 633.8381 "Keratin, type I cytoskeletal 14 OS=Homo sapiens OX=9606 GN=KRT14 PE=1 SV=4" 5.81 2308.5 - 3.54E+07 - - - -0.3611 - 1.916 0.357 - 258 1 2 1 -0.0005 10 0 0 0 4.12E+08 0.00E+00 - - - 3.4927 1 221125_WJC_METTL3_EV_vs_WT_F06.12598.12598.3 3.28E-08 16/60 M.AGGEAGVTLGQPHLSR[166.11].Q "sp|Q2VIR3|IF2GL_HUMAN,sp|P41091|IF2G_HUMAN,tr|H7BZU1|H7BZU1_HUMAN" 3 1558.8091 1.6 82021 12598 3 1558.806235 520.6103 Eukaryotic translation initiation factor 2 subunit 3B OS=Homo sapiens OX=9606 GN=EIF2S3B PE=2 SV=2 6.79 2308.7 - 2.42E+06 - - - -1.8533 - 3.319 0.476 - 364.9 1 2 0 -0.0029 16 0 0 0 4.05E+07 2.52E+07 - - - 6.9243 0.9997 221125_WJC_METTL3_EV_vs_WT_F06.12599.12599.2 3.21E-06 16-Dec R.GDFSVHISR.N "sp|O00746|NDKM_HUMAN,tr|Q4TT34|Q4TT34_HUMAN,tr|A0A087WVT9|A0A087WVT9_HUMAN,tr|F2Z2X0|F2Z2X0_HUMAN" 4 1016.5039 2.04 82022 12599 2 1016.506332 509.2592 "Nucleoside diphosphate kinase, mitochondrial OS=Homo sapiens OX=9606 GN=NME4 PE=1 SV=1" 6.74 2308.8 - 1.95E+06 - - - 2.3502 - 2.17 0.516 - 513.1 1 2 0 0.0024 9 0 0 0 6.74E+07 3.30E+07 - - - 5.0928 0.9998 221125_WJC_METTL3_EV_vs_WT_F06.12601.12601.3 3.99E-06 Oct-48 R.HESETTTSLVLER[166.11].S "sp|Q04837|SSBP_HUMAN,tr|C9J8J0|C9J8J0_HUMAN,tr|C9K0U8|C9K0U8_HUMAN,tr|A0A0G2JLD8|A0A0G2JLD8_HUMAN,tr|E7EUY5|E7EUY5_HUMAN" 5 1510.7503 3.31 82024 12601 3 1510.748096 504.5907 "Single-stranded DNA-binding protein, mitochondrial OS=Homo sapiens OX=9606 GN=SSBP1 PE=1 SV=1" 4.75 2308.9 - 1.52E+06 - - - -1.4397 - 2.005 0.384 - 143.6 1 2 0 -0.0022 13 0 0 0 4.02E+07 1.22E+07 - - - 4.7067 1 221125_WJC_METTL3_EV_vs_WT_F06.12603.12603.2 6.98E-12 18/34 R.GDSEPTPGC[160.03]SGLGPGGVR.G "sp|Q8WW01|SEN15_HUMAN,tr|E9PPN1|E9PPN1_HUMAN,tr|F2Z3M0|F2Z3M0_HUMAN,tr|A0A2U3TZM3|A0A2U3TZM3_HUMAN,tr|A0A2R8YG40|A0A2R8YG40_HUMAN,tr|H0YCV5|H0YCV5_HUMAN,tr|A0A2R8Y5L0|A0A2R8Y5L0_HUMAN,tr|A0A2R8YDU8|A0A2R8YDU8_HUMAN,tr|A0A2R8YHG0|A0A2R8YHG0_HUMAN,tr|A0A2R8Y6M5|A0A2R8Y6M5_HUMAN,tr|A0A2R8Y6B3|A0A2R8Y6B3_HUMAN,tr|A0A2R8YEM0|A0A2R8YEM0_HUMAN,tr|A0A2R8Y6A4|A0A2R8Y6A4_HUMAN" 13 1698.7631 1.13 82026 12603 2 1698.762756 850.3889 tRNA-splicing endonuclease subunit Sen15 OS=Homo sapiens OX=9606 GN=TSEN15 PE=1 SV=1 4.37 2309.2 - 1.26E+06 - - - -0.2308 - 2.997 0.739 - 712.5 1 2 0 -0.0004 18 0 0 0 1.27E+07 1.13E+07 - - - 7.1977 0.9998 221125_WJC_METTL3_EV_vs_WT_F06.12604.12604.2 5.24E-05 16-Sep K.DVNQQEFVR[166.11].A "sp|P39019|RS19_HUMAN,tr|M0R140|M0R140_HUMAN,tr|M0R2L9|M0R2L9_HUMAN,tr|M0QYF7|M0QYF7_HUMAN" 4 1143.5548 1.19 82027 12604 2 1143.554803 572.7847 40S ribosomal protein S19 OS=Homo sapiens OX=9606 GN=RPS19 PE=1 SV=2 4.37 2309.3 - 1.22E+06 - - - -0.0026 - 2.09 0.413 - 314.9 1 2 0 0 9 0 0 0 1.99E+07 1.68E+07 - - - 4.2241 0.9928 221125_WJC_METTL3_EV_vs_WT_F06.12605.12605.2 0.000351 13/20 S.KYEELQITAGR.H "sp|P04264|K2C1_HUMAN,sp|P04259|K2C6B_HUMAN" 2 1306.6881 11.5 82028 12605 2 1306.687215 654.3513 "Keratin, type II cytoskeletal 1 OS=Homo sapiens OX=9606 GN=KRT1 PE=1 SV=6" 6.14 2309.4 - 846469 - - - -0.6888 - 2.623 0.452 - 602.7 1 1 0 -0.0009 11 0 0 0 1.52E+07 1.33E+06 - - - 4.9879 1 221125_WJC_METTL3_EV_vs_WT_F06.12607.12607.2 1.76E-12 17/32 K.VYVGNLGNNGNK[136.11]TELER[166.11].A "sp|P84103|SRSF3_HUMAN,tr|A0A087X2D0|A0A087X2D0_HUMAN" 2 1893.9664 1.86 82030 12607 2 1893.969672 947.9905 Serine\arginine-rich splicing factor 3 OS=Homo sapiens OX=9606 GN=SRSF3 PE=1 SV=1 6.11 2309.7 - 501060 - - - 1.7492 - 3.269 0.693 - 813.6 1 2 1 0.0033 17 0 0 0 5.94E+06 3.20E+06 - - - 7.0706 0.9958 221125_WJC_METTL3_EV_vs_WT_F06.12611.12611.2 0.000282 18-Sep K.QKVENLFNEK.C "sp|P78347|GTF2I_HUMAN,tr|A0A494C1K3|A0A494C1K3_HUMAN" 2 1247.651 1.95 82032 12611 2 1247.650502 624.8328 General transcription factor II-I OS=Homo sapiens OX=9606 GN=GTF2I PE=1 SV=2 6.14 2310.2 - 2.76E+07 - - - -0.4 - 1.709 0.379 - 303.4 1 2 1 -0.0005 10 0 0 0 2.53E+08 1.30E+08 - - - 3.336 0.9952 221125_WJC_METTL3_EV_vs_WT_F06.12613.12613.3 5.83E-05 Dec-40 S.KYEELQITAGR.H "sp|P04264|K2C1_HUMAN,sp|P04259|K2C6B_HUMAN" 2 1306.6881 220.72 82034 12613 3 1306.68691 436.57 "Keratin, type II cytoskeletal 1 OS=Homo sapiens OX=9606 GN=KRT1 PE=1 SV=6" 6.14 2310.3 - 8.68E+06 - - - -0.9222 - 2.514 0.435 - 294.1 1 1 0 -0.0012 11 0 0 0 8.05E+07 3.65E+05 - - - 6.0084 0.9954 221125_WJC_METTL3_EV_vs_WT_F06.12614.12614.3 0.0561 14/60 M.AGGEAGVTLGQPHLSR.Q "sp|Q2VIR3|IF2GL_HUMAN,sp|P41091|IF2G_HUMAN,tr|H7BZU1|H7BZU1_HUMAN" 3 1548.8009 1.41 82035 12614 3 1548.797722 517.2742 Eukaryotic translation initiation factor 2 subunit 3B OS=Homo sapiens OX=9606 GN=EIF2S3B PE=2 SV=2 6.79 2310.3 - 3.39E+06 - - - -2.0222 - 1.76 0.241 - 169.6 1 2 0 -0.0031 16 0 0 0 3.54E+07 2.51E+07 - - - 2.6766 0.9986 221125_WJC_METTL3_EV_vs_WT_F06.12617.12617.3 0.012 Nov-36 K.WEVEEMKESK.L "sp|P27824|CALX_HUMAN,tr|A0A7P0T937|A0A7P0T937_HUMAN,tr|A0A7P0T840|A0A7P0T840_HUMAN,tr|A0A7P0Z4H2|A0A7P0Z4H2_HUMAN,tr|A0A7P0TB65|A0A7P0TB65_HUMAN,tr|A0A7P0TAN9|A0A7P0TAN9_HUMAN,tr|A0A7P0TAE9|A0A7P0TAE9_HUMAN,tr|A0A7P0T8N1|A0A7P0T8N1_HUMAN,tr|A0A7P0T8G1|A0A7P0T8G1_HUMAN,tr|A0A7P0Z4D6|A0A7P0Z4D6_HUMAN,tr|A0A7P0Z484|A0A7P0Z484_HUMAN,tr|A0A7P0TAR9|A0A7P0TAR9_HUMAN,tr|A0A7P0T9L0|A0A7P0T9L0_HUMAN,tr|D6RAU8|D6RAU8_HUMAN" 14 1293.5911 1.19 82038 12617 3 1293.589376 432.2043 Calnexin OS=Homo sapiens OX=9606 GN=CANX PE=1 SV=2 4.49 2310.5 - 1.89E+06 - - - -1.335 - 2.021 0.336 - 139 1 2 1 -0.0017 10 0 0 0 1.93E+07 1.62E+07 - - - 4.3404 1 221125_WJC_METTL3_EV_vs_WT_F06.12621.12621.3 4.07E-05 21/60 K.ALNGAEPNYHSLPSAR[166.11].T "sp|Q6IAA8|LTOR1_HUMAN,tr|F5GX19|F5GX19_HUMAN,tr|F5H3Y3|F5H3Y3_HUMAN,tr|H0YFI1|H0YFI1_HUMAN,tr|F5H479|F5H479_HUMAN" 5 1705.8412 2.27 82042 12621 3 1705.840634 569.621 Ragulator complex protein LAMTOR1 OS=Homo sapiens OX=9606 GN=LAMTOR1 PE=1 SV=2 6.79 2311.1 - 1.11E+06 - - - -0.3037 - 3.08 0.526 - 581 1 2 0 -0.0005 16 0 0 0 4.16E+07 1.83E+07 - - - 7.2907 0.9999 221125_WJC_METTL3_EV_vs_WT_F06.12622.12622.2 0.000197 16/20 K.KDLSQLQENLK.L sp|Q8IX12|CCAR1_HUMAN 1 1314.7143 8.15 82043 12622 2 1314.713524 658.3644 Cell division cycle and apoptosis regulator protein 1 OS=Homo sapiens OX=9606 GN=CCAR1 PE=1 SV=2 6.07 2311.2 - 1.07E+06 - - - -0.6131 - 3.352 0.454 - 819.5 1 2 0 -0.0008 11 0 0 0 2.02E+07 2.47E+06 - - - 5.6661 0.9944 221125_WJC_METTL3_EV_vs_WT_F06.12626.12626.2 6.86E-06 13/24 T.SNTSNLFGNSGAK.T "sp|P35658|NU214_HUMAN,tr|A0A494C0Y1|A0A494C0Y1_HUMAN,tr|A0A0A0MSW3|A0A0A0MSW3_HUMAN,tr|B7ZAV2|B7ZAV2_HUMAN,tr|A0A494C1F2|A0A494C1F2_HUMAN,tr|H0Y837|H0Y837_HUMAN" 6 1295.6106 2.23 82047 12626 2 1295.609942 648.8126 Nuclear pore complex protein Nup214 OS=Homo sapiens OX=9606 GN=NUP214 PE=1 SV=2 8.47 2311.7 - 935857 - - - -0.5025 - 2.758 0.512 - 670.7 1 1 0 -0.0007 13 0 0 0 7.35E+06 3.30E+06 - - - 5.4262 0.9999 221125_WJC_METTL3_EV_vs_WT_F06.12630.12630.2 2.49E-05 26-Nov R.GQTPAQAETNYLNK[136.11].A sp|Q9HCM4|E41L5_HUMAN 1 1541.7565 1.15 82051 12630 2 1541.757104 771.8855 Band 4.1-like protein 5 OS=Homo sapiens OX=9606 GN=EPB41L5 PE=1 SV=3 6 2312.2 - 442041 - - - 0.3684 - 2.203 0.519 - 296.4 1 2 0 0.0006 14 0 0 0 7.88E+06 6.84E+06 - - - 4.8562 0.9998 221125_WJC_METTL3_EV_vs_WT_F06.12639.12639.3 0.000494 Nov-40 K.K[136.11]DLSQLQENLK[136.11].L sp|Q8IX12|CCAR1_HUMAN 1 1330.7427 4.8 82058 12639 3 1330.741927 444.5882 Cell division cycle and apoptosis regulator protein 1 OS=Homo sapiens OX=9606 GN=CCAR1 PE=1 SV=2 6.07 2313 - 1.41E+06 - - - -0.6034 - 2.387 0.321 - 214.1 1 2 0 -0.0008 11 0 0 0 5.35E+07 1.11E+07 - - - 4.5902 1 221125_WJC_METTL3_EV_vs_WT_F06.12641.12641.2 8.97E-07 16/26 K.QTSDNLSEEC[160.03]QLAR.K "sp|Q6ULP2|AFTIN_HUMAN,tr|A0A0U1RR74|A0A0U1RR74_HUMAN,tr|B8ZZI9|B8ZZI9_HUMAN" 3 1649.7315 1.73 82060 12641 2 1649.727739 825.873 Aftiphilin OS=Homo sapiens OX=9606 GN=AFTPH PE=1 SV=3 4.14 2313.3 - 1.37E+06 - - - -2.2876 - 3.247 0.594 - 805 1 2 0 -0.0038 14 0 0 0 1.62E+07 9.36E+06 - - - 6.3826 0.9997 221125_WJC_METTL3_EV_vs_WT_F06.12642.12642.3 5.61E-05 16/52 K.YLQLQQEKEQELSK.L "sp|O00461|GOLI4_HUMAN,tr|F8W785|F8W785_HUMAN" 2 1762.9101 1.38 82061 12642 3 1762.907953 588.644 Golgi integral membrane protein 4 OS=Homo sapiens OX=9606 GN=GOLIM4 PE=1 SV=1 4.79 2313.4 - 1.36E+06 - - - -1.2343 - 2.557 0.437 - 166 1 2 1 -0.0022 14 0 0 0 1.18E+07 8.60E+06 - - - 5.9065 0.9997 221125_WJC_METTL3_EV_vs_WT_F06.12644.12644.3 0.000727 14/52 K.YLQLQQEK[136.11]EQELSK[136.11].L "sp|O00461|GOLI4_HUMAN,tr|F8W785|F8W785_HUMAN" 2 1778.9385 1.52 82063 12644 3 1778.938902 593.9868 Golgi integral membrane protein 4 OS=Homo sapiens OX=9606 GN=GOLIM4 PE=1 SV=1 4.79 2313.6 - 1.04E+06 - - - 0.2097 - 2.522 0.426 - 130.6 1 2 1 0.0004 14 0 0 0 1.31E+07 8.60E+06 - - - 5.7477 1 221125_WJC_METTL3_EV_vs_WT_F06.12647.12647.2 1.07E-06 26-Dec R.GQTPAQAETNYLNK.A sp|Q9HCM4|E41L5_HUMAN 1 1533.7423 1.13 82066 12647 2 1533.74283 767.8784 Band 4.1-like protein 5 OS=Homo sapiens OX=9606 GN=EPB41L5 PE=1 SV=3 6 2314 - 684747 - - - 0.3221 - 2.703 0.585 - 495.4 1 2 0 0.0005 14 0 0 0 8.38E+06 7.43E+06 - - - 5.857 1 221125_WJC_METTL3_EV_vs_WT_F06.12648.12648.2 1.03E-05 15/26 K.QTSDNLSEEC[160.03]QLAR[166.11].K "sp|Q6ULP2|AFTIN_HUMAN,tr|A0A0U1RR74|A0A0U1RR74_HUMAN,tr|B8ZZI9|B8ZZI9_HUMAN" 3 1659.7398 1.73 82067 12648 2 1659.740424 830.8772 Aftiphilin OS=Homo sapiens OX=9606 GN=AFTPH PE=1 SV=3 4.14 2314.1 - 565833 - - - 0.3862 - 2.983 0.573 - 641.5 1 2 0 0.0006 14 0 0 0 1.62E+07 9.36E+06 - - - 6.0156 0.9998 221125_WJC_METTL3_EV_vs_WT_F06.12649.12649.2 1.43E-08 28-Nov K.GNVFSSPTAAGTPNK[136.11].E "sp|Q05682|CALD1_HUMAN,tr|E7EX44|E7EX44_HUMAN,tr|A0A6Q8PGI1|A0A6Q8PGI1_HUMAN,tr|E9PGZ1|E9PGZ1_HUMAN" 4 1454.7245 0.47 82068 12649 2 1454.726695 728.3695 Caldesmon OS=Homo sapiens OX=9606 GN=CALD1 PE=1 SV=3 8.75 2314.3 - 533685 - - - 1.5041 - 2.356 0.581 - 310.7 1 2 0 0.0022 15 0 0 0 1.82E+06 3.89E+06 - - - 5.4385 0.9998 221125_WJC_METTL3_EV_vs_WT_F06.12653.12653.3 0.000247 15/60 K.ALNGAEPNYHSLPSAR.T "sp|Q6IAA8|LTOR1_HUMAN,tr|F5GX19|F5GX19_HUMAN,tr|F5H3Y3|F5H3Y3_HUMAN,tr|H0YFI1|H0YFI1_HUMAN,tr|F5H479|F5H479_HUMAN" 5 1695.8329 1.52 82070 12653 3 1695.833112 566.2849 Ragulator complex protein LAMTOR1 OS=Homo sapiens OX=9606 GN=LAMTOR1 PE=1 SV=2 6.79 2314.7 - 1.46E+06 - - - 0.1356 - 2.274 0.367 - 203.6 1 2 0 0.0002 16 0 0 0 2.43E+07 1.60E+07 - - - 4.7396 0.9998 221125_WJC_METTL3_EV_vs_WT_F06.12654.12654.3 0.00402 Aug-40 K.KDLSQLQENLK.L sp|Q8IX12|CCAR1_HUMAN 1 1314.7143 4.8 82071 12654 3 1314.713996 439.2454 Cell division cycle and apoptosis regulator protein 1 OS=Homo sapiens OX=9606 GN=CCAR1 PE=1 SV=2 6.07 2314.8 - 6.37E+06 - - - -0.254 - 2.058 0.34 - 138 1 2 0 -0.0003 11 0 0 0 5.35E+07 1.11E+07 - - - 4.3809 0.9924 221125_WJC_METTL3_EV_vs_WT_F06.12656.12656.3 0.00334 16/60 K.LKGEATVSFDDPPSAK.A "sp|P35637|FUS_HUMAN,tr|H3BPE7|H3BPE7_HUMAN" 2 1660.8308 1.14 82073 12656 3 1660.837077 554.6175 RNA-binding protein FUS OS=Homo sapiens OX=9606 GN=FUS PE=1 SV=1 4.56 2314.9 - 1.17E+06 - - - 3.7698 - 2.215 0.342 - 241.6 1 2 1 0.0063 16 0 0 0 3.08E+09 2.70E+09 - - - 4.3917 0.9999 221125_WJC_METTL3_EV_vs_WT_F06.12657.12657.3 1.41E-07 18/56 K.IFQKGESPVDYDGGR.T sp|Q15084|PDIA6_HUMAN 1 1666.7951 0.76 82074 12657 3 1666.796369 556.6056 Protein disulfide-isomerase A6 OS=Homo sapiens OX=9606 GN=PDIA6 PE=1 SV=1 4.56 2315 - 1.02E+06 - - - 0.7613 - 3.032 0.519 - 288.4 1 2 1 0.0013 15 0 0 0 9.04E+06 1.18E+07 - - - 7.2204 1 221125_WJC_METTL3_EV_vs_WT_F06.12661.12661.2 6.94E-08 15/32 K.TFDEC[160.03]VAEGGSDC[160.03]APEK[136.11].L sp|Q7LGA3|HS2ST_HUMAN 1 1878.7491 1.62 82078 12661 2 1878.745359 940.3818 Heparan sulfate 2-O-sulfotransferase 1 OS=Homo sapiens OX=9606 GN=HS2ST1 PE=1 SV=1 3.83 2315.6 - 697313 - - - -2.0146 - 2.571 0.615 - 403.1 1 2 0 -0.0038 17 0 0 0 1.32E+07 8.11E+06 - - - 5.9038 1 221125_WJC_METTL3_EV_vs_WT_F06.12663.12663.2 6.83E-07 24-Dec K.TEQGPQVDETQFK[136.11].K "sp|P05091|ALDH2_HUMAN,tr|S4R3S4|S4R3S4_HUMAN" 2 1513.714 0.9 82080 12663 2 1513.714377 757.8643 "Aldehyde dehydrogenase, mitochondrial OS=Homo sapiens OX=9606 GN=ALDH2 PE=1 SV=2" 4.14 2315.8 - 556292 - - - 0.2477 - 2.591 0.604 - 671.4 1 2 0 0.0004 13 0 0 0 3.62E+06 4.01E+06 - - - 5.9455 0.999 221125_WJC_METTL3_EV_vs_WT_F06.12667.12667.3 1.36E-05 16/60 K.LK[136.11]GEATVSFDDPPSAK[136.11].A "sp|P35637|FUS_HUMAN,tr|H3BPE7|H3BPE7_HUMAN" 2 1676.8592 1.14 82082 12667 3 1676.858048 559.9603 RNA-binding protein FUS OS=Homo sapiens OX=9606 GN=FUS PE=1 SV=1 4.56 2316.4 - 5.53E+06 - - - -0.6965 - 2.655 0.307 - 248 1 2 1 -0.0012 16 0 0 0 3.08E+09 2.70E+09 - - - 4.4678 0.9997 221125_WJC_METTL3_EV_vs_WT_F06.12668.12668.3 0.00139 Nov-40 K.RLDEELEDAEK.N "sp|Q15008|PSMD6_HUMAN,tr|C9J0E9|C9J0E9_HUMAN,tr|C9J7B7|C9J7B7_HUMAN" 3 1345.6361 0.55 82083 12668 3 1345.632954 449.5527 26S proteasome non-ATPase regulatory subunit 6 OS=Homo sapiens OX=9606 GN=PSMD6 PE=1 SV=1 4.08 2316.4 - 1.03E+06 - - - -2.3669 - 2.337 0.367 - 306.9 1 2 0 -0.0032 11 0 0 0 9.81E+06 1.77E+07 - - - 5.0423 0.9998 221125_WJC_METTL3_EV_vs_WT_F06.12670.12670.3 9.89E-05 Oct-40 K.R[166.11]LDEELEDAEK[136.11].N "sp|Q15008|PSMD6_HUMAN,tr|C9J0E9|C9J0E9_HUMAN,tr|C9J7B7|C9J7B7_HUMAN" 3 1363.6586 0.55 82085 12670 3 1363.658795 455.5601 26S proteasome non-ATPase regulatory subunit 6 OS=Homo sapiens OX=9606 GN=PSMD6 PE=1 SV=1 4.08 2316.5 - 2.40E+06 - - - 0.1364 - 2.23 0.336 - 197.6 1 2 0 0.0002 11 0 0 0 9.81E+06 1.79E+07 - - - 4.5644 0.9999 221125_WJC_METTL3_EV_vs_WT_F06.12671.12671.2 3.43E-07 13/26 R.SSFYPDGGDQETAK.T "sp|Q9NYF8|BCLF1_HUMAN,tr|H0YF00|H0YF00_HUMAN,tr|E9PKI6|E9PKI6_HUMAN,tr|A0A1W2PQ43|A0A1W2PQ43_HUMAN,tr|E9PK91|E9PK91_HUMAN,tr|E9PJA7|E9PJA7_HUMAN,tr|E9PK09|E9PK09_HUMAN,tr|E9PQN2|E9PQN2_HUMAN" 8 1500.6369 2.39 82086 12671 2 1500.635014 751.3257 Bcl-2-associated transcription factor 1 OS=Homo sapiens OX=9606 GN=BCLAF1 PE=1 SV=2 4.03 2316.6 - 2.36E+06 - - - -1.2355 - 1.965 0.623 - 334.1 1 2 0 -0.0019 14 0 0 0 1.12E+08 4.68E+07 - - - 5.337 0.9999 221125_WJC_METTL3_EV_vs_WT_F06.12673.12673.2 1.50E-05 16/20 K.R[166.11]LDEELEDAEK[136.11].N "sp|Q15008|PSMD6_HUMAN,tr|C9J0E9|C9J0E9_HUMAN,tr|C9J7B7|C9J7B7_HUMAN" 3 1363.6586 0.61 82088 12673 2 1363.65832 682.8366 26S proteasome non-ATPase regulatory subunit 6 OS=Homo sapiens OX=9606 GN=PSMD6 PE=1 SV=1 4.08 2316.9 - 1.93E+06 - - - -0.2119 - 2.977 0.489 - 978.3 1 2 0 -0.0003 11 0 0 0 1.05E+07 1.70E+07 - - - 5.6038 1 221125_WJC_METTL3_EV_vs_WT_F06.12675.12675.3 2.65E-05 14/56 K.YGGPPPGWEGPHPQR.G "sp|A0AV96|RBM47_HUMAN,tr|D6RBP6|D6RBP6_HUMAN,tr|D6RFL5|D6RFL5_HUMAN,tr|D6RA49|D6RA49_HUMAN,tr|D6RBS9|D6RBS9_HUMAN,tr|B7Z8Z7|B7Z8Z7_HUMAN,tr|D6R9M7|D6R9M7_HUMAN,tr|D6REZ6|D6REZ6_HUMAN,tr|D6R9D6|D6R9D6_HUMAN" 9 1630.7641 0.94 82090 12675 3 1630.766045 544.5953 RNA-binding protein 47 OS=Homo sapiens OX=9606 GN=RBM47 PE=1 SV=2 6.75 2317 - 1.70E+06 - - - 1.2086 - 2.461 0.553 - 217 1 2 0 0.002 15 0 0 0 4.64E+07 4.95E+07 - - - 7.0548 1 221125_WJC_METTL3_EV_vs_WT_F06.12677.12677.2 7.44E-13 18/32 K.TFDEC[160.03]VAEGGSDC[160.03]APEK.L sp|Q7LGA3|HS2ST_HUMAN 1 1870.7349 1.62 82092 12677 2 1870.733341 936.3747 Heparan sulfate 2-O-sulfotransferase 1 OS=Homo sapiens OX=9606 GN=HS2ST1 PE=1 SV=1 3.83 2317.3 - 1.13E+06 - - - -0.8569 - 3.733 0.761 - 1009.2 1 2 0 -0.0016 17 0 0 0 1.32E+07 8.11E+06 - - - 7.8997 1 221125_WJC_METTL3_EV_vs_WT_F06.12681.12681.2 8.12E-09 15/32 R.ENASPAPGTTAEEAMSR.G "sp|P46379|BAG6_HUMAN,tr|A0A7I2V508|A0A7I2V508_HUMAN,tr|H0Y710|H0Y710_HUMAN,tr|A0A7P0MQS5|A0A7P0MQS5_HUMAN,tr|A0A0G2JL47|A0A0G2JL47_HUMAN,tr|A0A024RCR6|A0A024RCR6_HUMAN,tr|A0A0G2JK23|A0A0G2JK23_HUMAN" 7 1717.7577 1.23 82096 12681 2 1717.754645 859.8861 Large proline-rich protein BAG6 OS=Homo sapiens OX=9606 GN=BAG6 PE=1 SV=2 4.25 2317.7 - 795957 - - - -1.7948 - 2.832 0.67 - 427 1 2 0 -0.0031 17 0 0 0 8.26E+06 6.70E+06 - - - 6.548 0.8423 221125_WJC_METTL3_EV_vs_WT_F06.12683.12683.2 0.0771 May-32 N.TNEEAGDGTTTATVLAR.S "sp|P10809|CH60_HUMAN,tr|C9JL25|C9JL25_HUMAN,tr|A0A7I2V2X6|A0A7I2V2X6_HUMAN,tr|A0A7I2YQK6|A0A7I2YQK6_HUMAN,tr|A0A7I2V599|A0A7I2V599_HUMAN,tr|E7EXB4|E7EXB4_HUMAN,tr|A0A7I2YQ71|A0A7I2YQ71_HUMAN,tr|E7ESH4|E7ESH4_HUMAN,tr|A0A7I2V5M1|A0A7I2V5M1_HUMAN,tr|A0A7I2V5K3|A0A7I2V5K3_HUMAN,tr|A0A7I2V369|A0A7I2V369_HUMAN" 11 1705.8119 1.61 82098 12683 2 1705.809207 853.9132 "60 kDa heat shock protein, mitochondrial OS=Homo sapiens OX=9606 GN=HSPD1 PE=1 SV=2" 4.14 2318 - 412961 - - - -1.5623 - 1.45 0.271 - 42.8 2 1 0 -0.0027 17 0 0 0 6.11E+06 3.79E+06 - - - 1.8208 0.9999 221125_WJC_METTL3_EV_vs_WT_F06.12688.12688.2 3.10E-06 26-Dec R.SSFYPDGGDQETAK[136.11].T "sp|Q9NYF8|BCLF1_HUMAN,tr|H0YF00|H0YF00_HUMAN,tr|E9PKI6|E9PKI6_HUMAN,tr|A0A1W2PQ43|A0A1W2PQ43_HUMAN,tr|E9PK91|E9PK91_HUMAN,tr|E9PJA7|E9PJA7_HUMAN,tr|E9PK09|E9PK09_HUMAN,tr|E9PQN2|E9PQN2_HUMAN" 8 1508.6511 2.39 82102 12688 2 1508.649108 755.3328 Bcl-2-associated transcription factor 1 OS=Homo sapiens OX=9606 GN=BCLAF1 PE=1 SV=2 4.03 2318.6 - 1.30E+06 - - - -1.2992 - 1.862 0.625 - 275.5 1 2 0 -0.002 14 0 0 0 1.12E+08 4.68E+07 - - - 5.2166 1 221125_WJC_METTL3_EV_vs_WT_F06.12693.12693.2 1.97E-06 19/30 K.LKGEATVSFDDPPSAK.A "sp|P35637|FUS_HUMAN,tr|H3BPE7|H3BPE7_HUMAN" 2 1660.8308 1.11 82107 12693 2 1660.830969 831.4227 RNA-binding protein FUS OS=Homo sapiens OX=9606 GN=FUS PE=1 SV=1 4.56 2319.1 - 904446 - - - 0.0921 - 3.286 0.53 - 726.4 1 2 1 0.0002 16 0 0 0 2.02E+08 1.82E+08 - - - 5.8804 0.9986 221125_WJC_METTL3_EV_vs_WT_F06.12694.12694.2 1.67E-07 21/30 K.LK[136.11]GEATVSFDDPPSAK[136.11].A "sp|P35637|FUS_HUMAN,tr|H3BPE7|H3BPE7_HUMAN" 2 1676.8592 1.11 82108 12694 2 1676.860182 839.4369 RNA-binding protein FUS OS=Homo sapiens OX=9606 GN=FUS PE=1 SV=1 4.56 2319.2 - 900416 - - - 0.5761 - 3.387 0.401 - 862.1 1 2 1 0.001 16 0 0 0 2.02E+08 1.82E+08 - - - 5.0018 0.9995 221125_WJC_METTL3_EV_vs_WT_F06.12695.12695.3 0.00146 16/48 R.VSLANLKPNPGSK.K "sp|Q9P015|RM15_HUMAN,tr|E5RHF4|E5RHF4_HUMAN" 2 1323.7511 1.51 82109 12695 3 1323.750987 442.2576 "39S ribosomal protein L15, mitochondrial OS=Homo sapiens OX=9606 GN=MRPL15 PE=1 SV=1" 10 2319.3 - 758462 - - - -0.0476 - 2.368 0.27 - 238.8 1 2 0 -0.0001 13 0 0 0 6.10E+07 4.04E+07 - - - 3.8875 0.995 221125_WJC_METTL3_EV_vs_WT_F06.12696.12696.3 0.000324 Dec-44 R.DGSFPSEPGLR[166.11]R[166.11].S sp|Q00587|BORG5_HUMAN 1 1336.6639 0.41 82110 12696 3 1336.664865 446.5619 Cdc42 effector protein 1 OS=Homo sapiens OX=9606 GN=CDC42EP1 PE=1 SV=1 6.07 2319.5 - 723678 - - - 0.7571 - 2.062 0.151 - 179.8 1 2 0 0.001 12 0 0 0 1.33E+07 3.21E+07 - - - 2.2291 1 221125_WJC_METTL3_EV_vs_WT_F06.12697.12697.2 4.30E-14 16/28 K.GDC[160.03]VEC[160.03]MAC[160.03]SDNTVR[166.11].A "sp|P34949|MPI_HUMAN,tr|H3BPB8|H3BPB8_HUMAN,tr|H3BP57|H3BP57_HUMAN,tr|F5GX71|F5GX71_HUMAN" 4 1782.6669 6.25 82111 12697 2 1782.662712 892.3407 Mannose-6-phosphate isomerase OS=Homo sapiens OX=9606 GN=MPI PE=1 SV=2 4.03 2319.6 - 528979 - - - -2.3465 - 3.029 0.793 - 1085.2 1 2 0 -0.0042 15 0 0 0 2.72E+07 4.34E+06 - - - 7.6214 1 221125_WJC_METTL3_EV_vs_WT_F06.12706.12706.2 0.000403 18/32 R.LLEGEDAHLSSQQASGQ.S sp|P08779|K1C16_HUMAN 1 1768.8228 - 82118 12706 2 1768.821964 885.4187 "Keratin, type I cytoskeletal 16 OS=Homo sapiens OX=9606 GN=KRT16 PE=1 SV=4" 4.13 2320.4 - 1.70E+06 - - - -0.4562 - 3.569 0.604 - 807.8 1 1 0 -0.0008 17 0 0 0 - - - - - 6.6299 0.9999 221125_WJC_METTL3_EV_vs_WT_F06.12707.12707.3 1.80E-06 Dec-40 K.NFYQEHPDLAR[166.11].R "sp|P17844|DDX5_HUMAN,tr|J3QR02|J3QR02_HUMAN,tr|X6RLV5|X6RLV5_HUMAN,tr|A0A7I2V507|A0A7I2V507_HUMAN,tr|J3KTA4|J3KTA4_HUMAN,tr|J3KTQ4|J3KTQ4_HUMAN,tr|A0A7I2V2S0|A0A7I2V2S0_HUMAN,tr|J3QRQ7|J3QRQ7_HUMAN" 8 1398.6556 1.87 82119 12707 3 1398.651212 467.2258 Probable ATP-dependent RNA helicase DDX5 OS=Homo sapiens OX=9606 GN=DDX5 PE=1 SV=1 5.32 2320.5 - 2.29E+06 - - - -3.1251 - 1.891 0.531 - 194.7 1 2 0 -0.0044 11 0 0 0 3.33E+07 1.78E+07 - - - 6.2688 0.9996 221125_WJC_METTL3_EV_vs_WT_F06.12708.12708.2 0.0446 22-Oct R.ASVPSVQIQGQR[166.11].L sp|Q86YP4|P66A_HUMAN 1 1278.692 1.73 82120 12708 2 1278.692668 640.3533 Transcriptional repressor p66-alpha OS=Homo sapiens OX=9606 GN=GATAD2A PE=1 SV=1 9.79 2320.6 - 1.43E+06 - - - 0.5467 - 2.028 0.349 - 379.9 1 2 0 0.0007 12 0 0 0 2.75E+07 1.59E+07 - - - 3.4789 0.9996 221125_WJC_METTL3_EV_vs_WT_F06.12709.12709.3 0.000443 14/44 K.FR[166.11]EIQQELSSGR[166.11].N "sp|P18583|SON_HUMAN,tr|J3QSZ5|J3QSZ5_HUMAN" 2 1468.7537 1.81 82121 12709 3 1468.754885 490.5919 Protein SON OS=Homo sapiens OX=9606 GN=SON PE=1 SV=4 6.14 2320.6 - 1.29E+06 - - - 0.7857 - 2.91 0.35 - 397.2 1 2 1 0.0012 12 0 0 0 1.49E+08 8.26E+07 - - - 5.4026 0.9995 221125_WJC_METTL3_EV_vs_WT_F06.12710.12710.3 0.00278 14/60 K.YQYGGLNSGRPVTPPR.T sp|P62140|PP1B_HUMAN 1 1760.8958 1.1 82122 12710 3 1760.894239 587.9725 Serine\threonine-protein phosphatase PP1-beta catalytic subunit OS=Homo sapiens OX=9606 GN=PPP1CB PE=1 SV=3 9.99 2320.8 - 1.27E+06 - - - -0.8961 - 1.984 0.314 - 157.5 1 2 0 -0.0016 16 0 0 0 1.23E+08 1.12E+08 - - - 3.7983 0.9988 221125_WJC_METTL3_EV_vs_WT_F06.12712.12712.3 0.00534 Oct-48 R.K[136.11]NPLPPSVGVVDK[136.11].K sp|Q8NC51|PAIRB_HUMAN 1 1364.7999 0.58 82124 12712 3 1364.80156 455.9406 Plasminogen activator inhibitor 1 RNA-binding protein OS=Homo sapiens OX=9606 GN=SERBP1 PE=1 SV=2 8.59 2320.9 - 1.17E+06 - - - 1.2522 - 1.799 0.289 - 99.9 1 2 0 0.0017 13 0 0 0 2.51E+07 4.34E+07 - - - 3.3537 0.9897 221125_WJC_METTL3_EV_vs_WT_F06.12713.12713.3 4.19E-06 Nov-44 T.SRPGISTFGYNR.N "sp|Q15434|RBMS2_HUMAN,tr|F8VQS9|F8VQS9_HUMAN,tr|F8VZR4|F8VZR4_HUMAN,tr|F8W1T6|F8W1T6_HUMAN" 4 1353.6789 0.24 82125 12713 3 1353.676348 452.2336 "RNA-binding motif, single-stranded-interacting protein 2 OS=Homo sapiens OX=9606 GN=RBMS2 PE=1 SV=1" 10.83 2321 - 1.04E+06 - - - -1.9207 - 2.355 0.433 - 156.2 1 1 0 -0.0026 12 0 0 0 1.81E+07 7.49E+07 - - - 5.741 0.7775 221125_WJC_METTL3_EV_vs_WT_F06.12714.12714.3 0.167 Oct-64 R.LLEGEDAHLSSQQASGQ.S sp|P08779|K1C16_HUMAN 1 1768.8228 - 82126 12714 3 1768.823121 590.6149 "Keratin, type I cytoskeletal 16 OS=Homo sapiens OX=9606 GN=KRT16 PE=1 SV=4" 4.13 2321.1 - 875772 - - - 0.1979 - 1.966 0.226 - 74.1 2 1 0 0.0003 17 0 0 0 - - - - - 2.628 1 221125_WJC_METTL3_EV_vs_WT_F06.12715.12715.2 1.28E-13 22/30 R.GPSGGGEEPALSQYQR.L "sp|Q99567|NUP88_HUMAN,tr|J3KMX1|J3KMX1_HUMAN" 2 1631.754 2.14 82127 12715 2 1631.754785 816.8843 Nuclear pore complex protein Nup88 OS=Homo sapiens OX=9606 GN=NUP88 PE=1 SV=2 4.53 2321.3 - 816918 - - - 0.5038 - 4.485 0.749 - 1297.7 1 2 0 0.0008 16 0 0 0 3.69E+07 1.72E+07 - - - 8.2625 0.9995 221125_WJC_METTL3_EV_vs_WT_F06.12717.12717.3 0.0065 Nov-60 R.LPPGFSASSTVEK[136.11]PSK[136.11].V "sp|O75694|NU155_HUMAN,tr|E9PF10|E9PF10_HUMAN" 2 1646.885 2.13 82129 12717 3 1646.881953 549.969 Nuclear pore complex protein Nup155 OS=Homo sapiens OX=9606 GN=NUP155 PE=1 SV=1 8.59 2321.5 - 424950 - - - -1.8726 - 1.947 0.359 - 134.5 1 2 0 -0.0031 16 0 0 0 1.78E+07 8.35E+06 - - - 4.2512 0.9992 221125_WJC_METTL3_EV_vs_WT_F06.12718.12718.2 0.000113 22-Nov K.QSLRPFC[160.03]TVC[160.03]NR.Y "sp|Q9ULV3|CIZ1_HUMAN,tr|Q5SYW2|Q5SYW2_HUMAN,tr|F5H2X7|F5H2X7_HUMAN,tr|H0Y5D5|H0Y5D5_HUMAN,tr|A0A0U1RQR2|A0A0U1RQR2_HUMAN,tr|A0A494C0L7|A0A494C0L7_HUMAN,tr|Q9BTG3|Q9BTG3_HUMAN" 7 1536.729 1.02 82130 12718 2 1536.730061 769.3718 Cip1-interacting zinc finger protein OS=Homo sapiens OX=9606 GN=CIZ1 PE=1 SV=2 9.02 2321.6 - 404010 - - - 0.7217 - 1.985 0.26 - 105.2 1 2 0 0.0011 12 0 0 0 7.49E+06 7.33E+06 - - - 2.765 0.9987 221125_WJC_METTL3_EV_vs_WT_F06.12719.12719.2 0.000171 15/22 K.FREIQQELSSGR.N "sp|P18583|SON_HUMAN,tr|J3QSZ5|J3QSZ5_HUMAN" 2 1448.7372 1.89 82131 12719 2 1448.737472 725.3759 Protein SON OS=Homo sapiens OX=9606 GN=SON PE=1 SV=4 6.14 2321.7 - 317540 - - - 0.194 - 2.756 0.447 - 238.9 1 2 1 0.0003 12 0 0 0 3.63E+07 1.92E+07 - - - 5.0099 1 221125_WJC_METTL3_EV_vs_WT_F06.12726.12726.3 5.54E-08 15/52 R.NALQQENHIIDGVK.V "sp|Q9GZT3|SLIRP_HUMAN,tr|H0YJW7|H0YJW7_HUMAN,tr|A0A087WUN7|A0A087WUN7_HUMAN,tr|G3V2S9|G3V2S9_HUMAN,tr|H0YJ40|H0YJ40_HUMAN,tr|G3V4X6|G3V4X6_HUMAN" 6 1577.8162 1.83 82136 12726 3 1577.81335 526.946 "SRA stem-loop-interacting RNA-binding protein, mitochondrial OS=Homo sapiens OX=9606 GN=SLIRP PE=1 SV=1" 5.32 2322.4 - 3.14E+06 - - - -1.7866 - 2.732 0.485 - 308.2 1 2 0 -0.0028 14 0 0 0 3.60E+07 1.97E+07 - - - 6.6174 1 221125_WJC_METTL3_EV_vs_WT_F06.12727.12727.3 8.97E-06 14/48 R.VSLANLK[136.11]PNPGSK[136.11].K "sp|Q9P015|RM15_HUMAN,tr|E5RHF4|E5RHF4_HUMAN" 2 1339.7794 1.51 82137 12727 3 1339.778524 447.6004 "39S ribosomal protein L15, mitochondrial OS=Homo sapiens OX=9606 GN=MRPL15 PE=1 SV=1" 10 2322.5 - 2.06E+06 - - - -0.6912 - 2.915 0.469 - 234.3 1 2 0 -0.0009 13 0 0 0 6.11E+07 4.04E+07 - - - 6.6694 1 221125_WJC_METTL3_EV_vs_WT_F06.12728.12728.2 2.82E-09 22/30 R.GPSGGGEEPALSQYQR[166.11].L "sp|Q99567|NUP88_HUMAN,tr|J3KMX1|J3KMX1_HUMAN" 2 1641.7622 2.14 82138 12728 2 1641.762189 821.8884 Nuclear pore complex protein Nup88 OS=Homo sapiens OX=9606 GN=NUP88 PE=1 SV=2 4.53 2322.6 - 1.52E+06 - - - -0.0268 - 4.423 0.681 - 1301.2 1 2 0 0 16 0 0 0 3.69E+07 1.72E+07 - - - 7.7263 0.9999 221125_WJC_METTL3_EV_vs_WT_F06.12729.12729.3 5.45E-07 14/60 K.YQYGGLNSGR[166.11]PVTPPR[166.11].T sp|P62140|PP1B_HUMAN 1 1780.9124 1.17 82139 12729 3 1780.912331 594.6447 Serine\threonine-protein phosphatase PP1-beta catalytic subunit OS=Homo sapiens OX=9606 GN=PPP1CB PE=1 SV=3 9.99 2322.7 - 1.44E+06 - - - -0.0146 - 2.306 0.447 - 172.3 1 2 0 0 16 0 0 0 1.34E+08 1.15E+08 - - - 5.6674 1 221125_WJC_METTL3_EV_vs_WT_F06.12730.12730.3 0.000369 Dec-32 K.HHPDLIFC[160.03]R.K sp|Q7RTV0|PHF5A_HUMAN 1 1193.5764 1.04 82140 12730 3 1193.575326 398.8661 PHD finger-like domain-containing protein 5A OS=Homo sapiens OX=9606 GN=PHF5A PE=1 SV=1 6.91 2322.9 - 1.07E+06 - - - -0.8973 - 2.42 0.44 - 245.6 1 2 0 -0.0011 9 0 0 0 3.01E+07 2.90E+07 - - - 6.1088 0.9984 221125_WJC_METTL3_EV_vs_WT_F06.12731.12731.2 0.000462 16/22 K.FR[166.11]EIQQELSSGR[166.11].N "sp|P18583|SON_HUMAN,tr|J3QSZ5|J3QSZ5_HUMAN" 2 1468.7537 1.89 82141 12731 2 1468.752009 735.3841 Protein SON OS=Homo sapiens OX=9606 GN=SON PE=1 SV=4 6.14 2323 - 987710 - - - -1.1724 - 2.924 0.434 - 250.4 1 2 1 -0.0017 12 0 0 0 3.63E+07 1.92E+07 - - - 5.0691 0.9984 221125_WJC_METTL3_EV_vs_WT_F06.12732.12732.2 0.000344 14/24 R.LKESAEFQTQLEK.K sp|P12270|TPR_HUMAN 1 1549.7988 8.26 82142 12732 2 1549.801104 775.9067 Nucleoprotein TPR OS=Homo sapiens OX=9606 GN=TPR PE=1 SV=3 4.79 2323.1 - 896510 - - - 1.4944 - 2.886 0.52 - 433.8 1 2 1 0.0023 13 0 0 0 7.82E+06 9.48E+05 - - - 5.6012 0.9999 221125_WJC_METTL3_EV_vs_WT_F06.12735.12735.3 5.43E-05 Nov-48 K.QVK[136.11]PLPAPLDGQR[166.11].K "sp|Q8WWY3|PRP31_HUMAN,tr|E7EVX8|E7EVX8_HUMAN" 2 1435.8266 2.61 82144 12735 3 1435.824434 479.6161 U4\U6 small nuclear ribonucleoprotein Prp31 OS=Homo sapiens OX=9606 GN=PRPF31 PE=1 SV=2 8.75 2323.5 - 2.31E+06 - - - -1.5211 - 1.93 0.441 - 188 1 2 0 -0.0022 13 0 0 0 1.83E+08 7.00E+07 - - - 5.2388 0.9999 221125_WJC_METTL3_EV_vs_WT_F06.12740.12740.3 0.00049 14/32 K.HHPDLIFC[160.03]R[166.11].K sp|Q7RTV0|PHF5A_HUMAN 1 1203.5847 1.05 82148 12740 3 1203.583015 402.2022 PHD finger-like domain-containing protein 5A OS=Homo sapiens OX=9606 GN=PHF5A PE=1 SV=1 6.91 2323.9 - 970295 - - - -1.3726 - 2.301 0.443 - 318.2 1 2 0 -0.0017 9 0 0 0 3.01E+07 2.87E+07 - - - 5.9901 1 221125_WJC_METTL3_EV_vs_WT_F06.12742.12742.2 0.000948 27/48 K.ASPAGTAGGPGAGAAAGGTGPLAAR.A sp|Q12962|TAF10_HUMAN 1 1962.9872 1.52 82150 12742 2 1962.986996 982.5009 Transcription initiation factor TFIID subunit 10 OS=Homo sapiens OX=9606 GN=TAF10 PE=1 SV=1 9.79 2324.1 - 876197 - - - -0.079 - 4.822 0.672 - 1973 1 2 0 -0.0002 25 0 0 0 4.34E+07 2.86E+07 - - - 7.8721 0.9994 221125_WJC_METTL3_EV_vs_WT_F06.12743.12743.2 0.000659 24-Oct K.QVKPLPAPLDGQR.K "sp|Q8WWY3|PRP31_HUMAN,tr|E7EVX8|E7EVX8_HUMAN" 2 1417.8041 6.03 82151 12743 2 1417.80519 709.9094 U4\U6 small nuclear ribonucleoprotein Prp31 OS=Homo sapiens OX=9606 GN=PRPF31 PE=1 SV=2 8.75 2324.3 - 702810 - - - 0.7349 - 1.638 0.366 - 247.6 1 2 0 0.001 13 0 0 0 1.41E+07 2.34E+06 - - - 3.0105 1 221125_WJC_METTL3_EV_vs_WT_F06.12750.12750.3 1.29E-12 37/96 K.ASPAGTAGGPGAGAAAGGTGPLAAR.A sp|Q12962|TAF10_HUMAN 1 1962.9872 1.44 82156 12750 3 1962.986584 655.3363 Transcription initiation factor TFIID subunit 10 OS=Homo sapiens OX=9606 GN=TAF10 PE=1 SV=1 9.79 2325.2 - 2.74E+06 - - - -0.2888 - 5.587 0.619 - 1378.2 1 2 0 -0.0006 25 0 0 0 9.39E+07 6.53E+07 - - - 9.3992 0.9888 221125_WJC_METTL3_EV_vs_WT_F06.12751.12751.3 0.709 Dec-44 K.DVTDKPLDLSSK.V "sp|Q6W2J9|BCOR_HUMAN,tr|H7BZ37|H7BZ37_HUMAN,tr|H7C2V9|H7C2V9_HUMAN,tr|H7BYY2|H7BYY2_HUMAN,tr|H7C231|H7C231_HUMAN" 5 1316.6824 1.66 82157 12751 3 1316.68582 439.9014 BCL-6 corepressor OS=Homo sapiens OX=9606 GN=BCOR PE=1 SV=1 4.43 2325.2 - 3.38E+06 - - - 2.6271 - 1.775 0.204 - 130.3 1 2 0 0.0035 12 0 0 0 2.23E+08 1.34E+08 - - - 2.4039 0.9999 221125_WJC_METTL3_EV_vs_WT_F06.12752.12752.3 0.000351 Nov-44 K.DVTDK[136.11]PLDLSSK[136.11].V "sp|Q6W2J9|BCOR_HUMAN,tr|H7BZ37|H7BZ37_HUMAN,tr|H7C2V9|H7C2V9_HUMAN,tr|H7BYY2|H7BYY2_HUMAN,tr|H7C231|H7C231_HUMAN" 5 1332.7108 1.66 82158 12752 3 1332.710289 445.2442 BCL-6 corepressor OS=Homo sapiens OX=9606 GN=BCOR PE=1 SV=1 4.43 2325.3 - 2.12E+06 - - - -0.3542 - 2.03 0.416 - 109.5 1 2 0 -0.0005 12 0 0 0 2.23E+08 1.34E+08 - - - 5.1404 0.9999 221125_WJC_METTL3_EV_vs_WT_F06.12753.12753.3 0.000755 14/48 K.TFSSSSALQIHER.T "sp|Q9NSC2|SALL1_HUMAN,tr|H3BSM9|H3BSM9_HUMAN" 2 1461.7212 1.76 82159 12753 3 1461.717991 488.2477 Sal-like protein 1 OS=Homo sapiens OX=9606 GN=SALL1 PE=1 SV=2 6.41 2325.4 - 1.99E+06 - - - -2.1995 - 2.773 0.389 - 194.3 1 2 0 -0.0032 13 0 0 0 4.24E+07 2.41E+07 - - - 5.6414 1 221125_WJC_METTL3_EV_vs_WT_F06.12754.12754.3 1.25E-09 17/48 K.C[160.03]EHDPHVLLAVAK.L sp|O94906|PRP6_HUMAN 1 1487.7555 1.75 82160 12754 3 1487.747427 496.9258 Pre-mRNA-processing factor 6 OS=Homo sapiens OX=9606 GN=PRPF6 PE=1 SV=1 5.99 2325.5 - 1.01E+06 - - - -5.4155 - 2.9 0.636 - 424.3 1 2 0 -0.0081 13 0 0 0 7.70E+06 4.41E+06 - - - 8.5153 0.9997 221125_WJC_METTL3_EV_vs_WT_F06.12755.12755.2 1.97E-05 26-Aug R.NALQQENHIIDGVK.V "sp|Q9GZT3|SLIRP_HUMAN,tr|H0YJW7|H0YJW7_HUMAN,tr|A0A087WUN7|A0A087WUN7_HUMAN,tr|G3V2S9|G3V2S9_HUMAN,tr|H0YJ40|H0YJ40_HUMAN,tr|G3V4X6|G3V4X6_HUMAN" 6 1577.8162 -1 82161 12755 2 1577.814637 789.9154 "SRA stem-loop-interacting RNA-binding protein, mitochondrial OS=Homo sapiens OX=9606 GN=SLIRP PE=1 SV=1" 5.32 2325.6 - 445832 - - - -0.971 - 1.805 0.453 - 192.2 1 2 0 -0.0015 14 0 0 0 0.00E+00 0.00E+00 - - - 3.8684 0.9999 221125_WJC_METTL3_EV_vs_WT_F06.12758.12758.3 8.69E-05 Dec-44 K.QSLRPFC[160.03]TVC[160.03]NR.Y "sp|Q9ULV3|CIZ1_HUMAN,tr|Q5SYW2|Q5SYW2_HUMAN,tr|F5H2X7|F5H2X7_HUMAN,tr|H0Y5D5|H0Y5D5_HUMAN,tr|A0A0U1RQR2|A0A0U1RQR2_HUMAN,tr|A0A494C0L7|A0A494C0L7_HUMAN,tr|Q9BTG3|Q9BTG3_HUMAN" 7 1536.729 2.43 82162 12758 3 1536.729005 513.2503 Cip1-interacting zinc finger protein OS=Homo sapiens OX=9606 GN=CIZ1 PE=1 SV=2 9.02 2326 - 5.70E+06 - - - 0.0345 - 1.986 0.468 - 161.8 1 2 0 0.0001 12 0 0 0 1.44E+08 5.92E+07 - - - 5.6596 0.9998 221125_WJC_METTL3_EV_vs_WT_F06.12759.12759.3 1.97E-06 13/60 K.LKGEATVSFDDPPSAK[136.11].A "sp|P35637|FUS_HUMAN,tr|H3BPE7|H3BPE7_HUMAN" 2 1668.845 - 82163 12759 3 1668.844303 557.2889 RNA-binding protein FUS OS=Homo sapiens OX=9606 GN=FUS PE=1 SV=1 4.56 2326.1 - 3.52E+06 - - - -0.4272 - 2.372 0.474 - 157 1 2 1 -0.0007 16 0 0 0 - - - - - 6.0407 0.9974 221125_WJC_METTL3_EV_vs_WT_F06.12760.12760.3 0.232 Nov-56 K.QTLENER[166.11]GELANEVK[136.11].V sp|P35579|MYH9_HUMAN 1 1746.8867 1.05 82164 12760 3 1746.88512 583.3028 Myosin-9 OS=Homo sapiens OX=9606 GN=MYH9 PE=1 SV=4 4.49 2326.1 - 3.06E+06 - - - -0.9113 - 2.326 0.267 - 156.7 1 2 1 -0.0016 15 0 0 0 7.85E+07 7.48E+07 - - - 3.719 1 221125_WJC_METTL3_EV_vs_WT_F06.12763.12763.2 4.85E-10 25/48 K.ASPAGTAGGPGAGAAAGGTGPLAAR[166.11].A sp|Q12962|TAF10_HUMAN 1 1972.9954 1.51 82167 12763 2 1972.993259 987.505 Transcription initiation factor TFIID subunit 10 OS=Homo sapiens OX=9606 GN=TAF10 PE=1 SV=1 9.79 2326.5 - 997615 - - - -1.0958 - 4.707 0.687 - 1439.3 1 2 0 -0.0022 25 0 0 0 4.33E+07 2.86E+07 - - - 7.9229 1 221125_WJC_METTL3_EV_vs_WT_F06.12766.12766.2 9.01E-09 16/32 K.AASSQTPTMC[160.03]TTTVTVK.L sp|Q08554|DSC1_HUMAN 1 1782.8492 999 82170 12766 2 1782.847156 892.4319 Desmocollin-1 OS=Homo sapiens OX=9606 GN=DSC1 PE=1 SV=2 8.27 2326.9 - 413563 - - - -1.1386 - 3.179 0.673 - 617.6 1 2 0 -0.002 17 0 0 0 7.72E+06 0.00E+00 - - - 6.8546 0.9999 221125_WJC_METTL3_EV_vs_WT_F06.12769.12769.3 1.85E-06 Dec-40 R.GYDR[166.11]YEDYDYR[166.11].Y sp|Q13595|TRA2A_HUMAN 1 1533.6275 1.58 82171 12769 3 1533.626112 512.2165 Transformer-2 protein homolog alpha OS=Homo sapiens OX=9606 GN=TRA2A PE=1 SV=1 4.23 2327.3 - 4.70E+06 - - - -0.9226 - 2.217 0.615 - 151.4 1 2 1 -0.0014 11 0 0 0 9.62E+07 6.09E+07 - - - 7.658 1 221125_WJC_METTL3_EV_vs_WT_F06.12770.12770.3 4.06E-10 18/64 K.VYAC[160.03]EVTHQGLSSPVTK.S "sp|P01834|IGKC_HUMAN,tr|A0A5H1ZRQ3|A0A5H1ZRQ3_HUMAN" 2 1874.9196 79.15 82172 12770 3 1874.917936 625.9805 Immunoglobulin kappa constant OS=Homo sapiens OX=9606 GN=IGKC PE=1 SV=2 6.71 2327.3 - 3.89E+06 - - - -0.9136 - 3.521 0.677 - 265.6 1 2 0 -0.0017 17 0 0 0 1.53E+08 1.94E+06 - - - 9.2674 0.9999 221125_WJC_METTL3_EV_vs_WT_F06.12771.12771.3 0.00148 14/52 R.TYVPALEQSADGHK.E sp|P98175|RBM10_HUMAN 1 1514.7365 1.27 82173 12771 3 1514.737518 505.9195 RNA-binding protein 10 OS=Homo sapiens OX=9606 GN=RBM10 PE=1 SV=3 5.29 2327.4 - 1.07E+07 - - - 0.6575 - 2.358 0.429 - 160.5 1 2 0 0.001 14 0 0 0 2.29E+08 1.80E+08 - - - 5.6023 0.9999 221125_WJC_METTL3_EV_vs_WT_F06.12773.12773.3 9.45E-06 14/40 K.LQLLEDDKENR.Y "sp|P09874|PARP1_HUMAN,tr|A0A7I2V3E1|A0A7I2V3E1_HUMAN" 2 1371.6994 0.12 82175 12773 3 1371.699221 458.2404 Poly [ADP-ribose] polymerase 1 OS=Homo sapiens OX=9606 GN=PARP1 PE=1 SV=4 4.32 2327.5 - 2.55E+06 - - - -0.1363 - 3.092 0.522 - 302 1 2 1 -0.0002 11 0 0 0 1.96E+08 1.61E+09 - - - 7.5665 0.9996 221125_WJC_METTL3_EV_vs_WT_F06.12779.12779.3 1.10E-06 15/44 R.DYRNDPYEQDIR.E "sp|Q96T58|MINT_HUMAN,tr|A0A669KB49|A0A669KB49_HUMAN" 2 1582.7012 0.19 82179 12779 3 1582.694855 528.5743 Msx2-interacting protein OS=Homo sapiens OX=9606 GN=SPEN PE=1 SV=1 4.23 2328.2 - 947128 - - - -4.0083 - 2.816 0.579 - 326.8 1 2 1 -0.0063 12 0 0 0 1.46E+07 7.80E+07 - - - 7.8633 0.9941 221125_WJC_METTL3_EV_vs_WT_F06.12781.12781.3 0.0591 14/68 K.APAQTPAEPTPGYEVGQR.K "sp|P49815|TSC2_HUMAN,tr|A0A2R8Y7C8|A0A2R8Y7C8_HUMAN,tr|A0A2R8YDR3|A0A2R8YDR3_HUMAN,tr|A0A2R8Y7X5|A0A2R8Y7X5_HUMAN,tr|A0A2R8YDZ2|A0A2R8YDZ2_HUMAN,tr|A0A2R8YGD6|A0A2R8YGD6_HUMAN,tr|X5D2U8|X5D2U8_HUMAN,tr|A0A2R8Y5F1|A0A2R8Y5F1_HUMAN,tr|A0A2R8YGU4|A0A2R8YGU4_HUMAN,tr|H3BMQ0|H3BMQ0_HUMAN,tr|A0A2R8Y6C9|A0A2R8Y6C9_HUMAN" 11 1867.9064 0.36 82181 12781 3 1867.9055 623.6428 Tuberin OS=Homo sapiens OX=9606 GN=TSC2 PE=1 SV=2 4.53 2328.5 - 526580 - - - -0.5038 - 1.874 0.182 - 65 1 2 0 -0.0009 18 0 0 0 9.59E+06 2.68E+07 - - - 2.1328 1 221125_WJC_METTL3_EV_vs_WT_F06.12785.12785.3 9.64E-06 13/44 K.HIGVC[160.03]ISVANNR[166.11].L "sp|O60506|HNRPQ_HUMAN,sp|O43390|HNRPR_HUMAN,tr|A0A7I2YQV8|A0A7I2YQV8_HUMAN,tr|B4DT28|B4DT28_HUMAN,tr|A0A7I2YQN2|A0A7I2YQN2_HUMAN,tr|A0A7I2V5Q6|A0A7I2V5Q6_HUMAN,tr|A0A7I2V4Z0|A0A7I2V4Z0_HUMAN,tr|A0A6Q8PHG0|A0A6Q8PHG0_HUMAN,tr|B7Z645|B7Z645_HUMAN,tr|A0A6Q8PH31|A0A6Q8PH31_HUMAN,tr|A0A6Q8PEX7|A0A6Q8PEX7_HUMAN,tr|A0A7I2V2F2|A0A7I2V2F2_HUMAN,tr|A0A7I2V346|A0A7I2V346_HUMAN,tr|A0A7I2V309|A0A7I2V309_HUMAN" 14 1348.6909 1.11 82183 12785 3 1348.691847 450.5709 Heterogeneous nuclear ribonucleoprotein Q OS=Homo sapiens OX=9606 GN=SYNCRIP PE=1 SV=2 8.26 2329 - 1.10E+06 - - - 0.6851 - 2.746 0.5 - 363.8 1 2 0 0.0009 12 0 0 0 2.01E+07 1.82E+07 - - - 6.9142 0.8577 221125_WJC_METTL3_EV_vs_WT_F06.12787.12787.3 0.3 Jul-56 K.QTLENERGELANEVK.V sp|P35579|MYH9_HUMAN 1 1728.8642 1.05 82185 12787 3 1728.863907 577.2954 Myosin-9 OS=Homo sapiens OX=9606 GN=MYH9 PE=1 SV=4 4.49 2329.2 - 5.76E+06 - - - -0.1938 - 1.341 0.158 - 40.8 1 2 1 -0.0003 15 0 0 0 7.87E+07 7.48E+07 - - - 1.0671 0.9999 221125_WJC_METTL3_EV_vs_WT_F06.12788.12788.2 2.07E-06 22-Nov K.ASTSDYQVISDR.Q sp|Q8NFH5|NUP35_HUMAN 1 1340.6208 2.65 82186 12788 2 1340.619394 671.3177 Nucleoporin NUP35 OS=Homo sapiens OX=9606 GN=NUP35 PE=1 SV=1 4.21 2329.3 - 1.26E+06 - - - -1.0667 - 2.38 0.568 - 679.7 1 2 0 -0.0014 12 0 0 0 1.70E+07 6.40E+06 - - - 5.5173 1 221125_WJC_METTL3_EV_vs_WT_F06.12792.12792.2 1.39E-11 15/30 K.IPSTENSSQEISVEER.T sp|Q96T58|MINT_HUMAN 1 1803.8487 1.4 82188 12792 2 1803.84639 902.9316 Msx2-interacting protein OS=Homo sapiens OX=9606 GN=SPEN PE=1 SV=1 4.09 2329.8 - 366410 - - - -1.2534 - 3.19 0.714 - 735 1 2 0 -0.0023 16 0 0 0 6.00E+06 4.27E+06 - - - 7.1659 0.9998 221125_WJC_METTL3_EV_vs_WT_F06.12793.12793.2 2.69E-06 13/22 K.DVTDK[136.11]PLDLSSK[136.11].V "sp|Q6W2J9|BCOR_HUMAN,tr|H7BZ37|H7BZ37_HUMAN,tr|H7C2V9|H7C2V9_HUMAN,tr|H7BYY2|H7BYY2_HUMAN,tr|H7C231|H7C231_HUMAN" 5 1332.7108 2.08 82189 12793 2 1332.713182 667.3627 BCL-6 corepressor OS=Homo sapiens OX=9606 GN=BCOR PE=1 SV=1 4.43 2329.9 - 1.72E+06 - - - 1.8166 - 2.591 0.551 - 525.1 1 2 0 0.0024 12 0 0 0 8.35E+07 4.01E+07 - - - 5.6149 0.9988 221125_WJC_METTL3_EV_vs_WT_F06.12794.12794.2 0.00602 20-Nov K.LQLLEDDKENR.Y "sp|P09874|PARP1_HUMAN,tr|A0A7I2V3E1|A0A7I2V3E1_HUMAN" 2 1371.6994 1.24 82190 12794 2 1371.698707 686.857 Poly [ADP-ribose] polymerase 1 OS=Homo sapiens OX=9606 GN=PARP1 PE=1 SV=4 4.32 2330 - 939664 - - - -0.511 - 2.428 0.507 - 533.2 1 2 1 -0.0007 11 0 0 0 1.95E+07 1.57E+07 - - - 5.1852 1 221125_WJC_METTL3_EV_vs_WT_F06.12795.12795.3 6.07E-10 19/60 R.IFREEQNGEDEDGGWR.L "sp|Q6Y7W6|GGYF2_HUMAN,tr|I1E4Y6|I1E4Y6_HUMAN,tr|A0A7I2V516|A0A7I2V516_HUMAN,tr|A0A7I2V3H0|A0A7I2V3H0_HUMAN,tr|C9JHW1|C9JHW1_HUMAN,tr|E7ESB6|E7ESB6_HUMAN" 6 1935.8347 3.15 82191 12795 3 1935.83502 646.2855 GRB10-interacting GYF protein 2 OS=Homo sapiens OX=9606 GN=GIGYF2 PE=1 SV=1 4.08 2330.2 - 520014 - - - 0.1483 - 3.814 0.664 - 554 1 2 1 0.0003 16 0 0 0 3.65E+07 1.16E+07 - - - 9.3777 0.9563 221125_WJC_METTL3_EV_vs_WT_F06.12798.12798.3 5.06E-05 Dec-40 A.SWADIASKPAK.Q sp|Q9Y5A9|YTHD2_HUMAN 1 1172.619 1.23 82194 12798 3 1172.618568 391.8803 YTH domain-containing family protein 2 OS=Homo sapiens OX=9606 GN=YTHDF2 PE=1 SV=2 8.31 2330.6 - 348095 - - - -0.3454 - 2.023 0.304 - 193.5 1 1 0 -0.0004 11 0 0 0 8.71E+06 7.06E+06 - - - 3.9308 0.9988 221125_WJC_METTL3_EV_vs_WT_F06.12801.12801.3 5.83E-05 15/44 K.LTSDDVKEQIYK.L "sp|P62277|RS13_HUMAN,tr|J3KMX5|J3KMX5_HUMAN,tr|E9PS50|E9PS50_HUMAN" 3 1437.7351 1 82195 12801 3 1437.733819 480.2523 40S ribosomal protein S13 OS=Homo sapiens OX=9606 GN=RPS13 PE=1 SV=2 4.56 2331 - 2.48E+06 - - - -0.9084 - 2.506 0.294 - 396.9 1 2 1 -0.0013 12 0 0 0 1.32E+08 1.31E+08 - - - 4.3639 1 221125_WJC_METTL3_EV_vs_WT_F06.12802.12802.3 1.83E-08 15/52 R.YEHALSQC[160.03]SVDVYK[136.11].K "sp|Q14203|DCTN1_HUMAN,tr|A0A804CDA6|A0A804CDA6_HUMAN,tr|E7EX90|E7EX90_HUMAN,tr|A0A7P0Z4C3|A0A7P0Z4C3_HUMAN,tr|Q6AWB1|Q6AWB1_HUMAN" 5 1705.7861 1.43 82196 12802 3 1705.786073 569.6027 Dynactin subunit 1 OS=Homo sapiens OX=9606 GN=DCTN1 PE=1 SV=3 5.32 2331.1 - 1.34E+06 - - - -0.0287 - 2.896 0.551 - 395.5 1 2 0 0 14 0 0 0 2.56E+07 1.79E+07 - - - 7.5089 0.9999 221125_WJC_METTL3_EV_vs_WT_F06.12803.12803.3 0.000268 Nov-52 R.YEHALSQC[160.03]SVDVYK.K "sp|Q14203|DCTN1_HUMAN,tr|A0A804CDA6|A0A804CDA6_HUMAN,tr|E7EX90|E7EX90_HUMAN,tr|A0A7P0Z4C3|A0A7P0Z4C3_HUMAN,tr|Q6AWB1|Q6AWB1_HUMAN" 5 1697.7719 1.43 82197 12803 3 1697.773545 566.9313 Dynactin subunit 1 OS=Homo sapiens OX=9606 GN=DCTN1 PE=1 SV=3 5.32 2331.2 - 2.29E+06 - - - 0.956 - 2.067 0.407 - 149.7 1 2 0 0.0016 14 0 0 0 2.56E+07 1.79E+07 - - - 5.0068 0.9997 221125_WJC_METTL3_EV_vs_WT_F06.12804.12804.3 0.00239 Nov-40 R.QSLETQYLQHR.L sp|Q9H0K1|SIK2_HUMAN 1 1401.7001 0.75 82198 12804 3 1401.69999 468.2406 Serine\threonine-protein kinase SIK2 OS=Homo sapiens OX=9606 GN=SIK2 PE=1 SV=1 6.75 2331.2 - 1.60E+06 - - - -0.0621 - 2.041 0.319 - 254.7 1 2 0 -0.0001 11 0 0 0 2.96E+07 3.95E+07 - - - 4.1233 0.9987 221125_WJC_METTL3_EV_vs_WT_F06.12807.12807.2 0.000608 13/22 K.LTSDDVK[136.11]EQIYK[136.11].L "sp|P62277|RS13_HUMAN,tr|J3KMX5|J3KMX5_HUMAN,tr|E9PS50|E9PS50_HUMAN" 3 1453.7635 0.99 82201 12807 2 1453.762018 727.889 40S ribosomal protein S13 OS=Homo sapiens OX=9606 GN=RPS13 PE=1 SV=2 4.56 2331.6 - 662041 - - - -1.0366 - 2.687 0.496 - 571.9 1 2 1 -0.0015 12 0 0 0 2.38E+07 2.40E+07 - - - 5.3047 0.9995 221125_WJC_METTL3_EV_vs_WT_F06.12809.12809.3 0.00486 Oct-76 K.ASESSK[136.11]PWPDATYGTGSASR[166.11].A "sp|Q9Y2W1|TR150_HUMAN,tr|A0A3B3ITZ9|A0A3B3ITZ9_HUMAN" 2 2071.9566 4.63 82203 12809 3 2071.959616 691.6595 Thyroid hormone receptor-associated protein 3 OS=Homo sapiens OX=9606 GN=THRAP3 PE=1 SV=2 6.11 2331.9 - 397205 - - - 1.4643 - 2.078 0.332 - 88.1 1 2 0 0.003 20 0 0 0 9.55E+06 2.06E+06 - - - 4.015 1 221125_WJC_METTL3_EV_vs_WT_F06.12813.12813.2 3.14E-07 16/26 R.QAVTNPNNTFYATK[136.11].R "sp|P38646|GRP75_HUMAN,tr|H0Y8K0|H0Y8K0_HUMAN,tr|A0A7I2V2S7|A0A7I2V2S7_HUMAN,tr|A0A7I2V2G2|A0A7I2V2G2_HUMAN,tr|A0A3B3ITI4|A0A3B3ITI4_HUMAN,tr|A0A7I2V3F7|A0A7I2V3F7_HUMAN,tr|A0A7I2YQB2|A0A7I2YQB2_HUMAN,tr|D6RCD7|D6RCD7_HUMAN" 8 1575.7773 0.55 82205 12813 2 1575.777253 788.8959 "Stress-70 protein, mitochondrial OS=Homo sapiens OX=9606 GN=HSPA9 PE=1 SV=2" 8.59 2332.4 - 987838 - - - -0.0114 - 3.076 0.639 - 979.3 1 2 0 0 14 0 0 0 5.38E+07 9.73E+07 - - - 6.5803 0.9994 221125_WJC_METTL3_EV_vs_WT_F06.12814.12814.4 0.000176 15/78 R.QIILEK[136.11]EETEELK[136.11]R[166.11].F "sp|P12956|XRCC6_HUMAN,tr|B1AHC9|B1AHC9_HUMAN" 2 1782.9938 0.31 82206 12814 4 1782.992767 446.7557 X-ray repair cross-complementing protein 6 OS=Homo sapiens OX=9606 GN=XRCC6 PE=1 SV=2 4.65 2332.4 - 2.82E+06 - - - -0.5513 - 2.79 0.391 - 160.9 1 2 1 -0.001 14 0 0 0 1.19E+07 3.83E+07 - - - 3.0024 1 221125_WJC_METTL3_EV_vs_WT_F06.12816.12816.2 9.54E-09 13/30 K.IPSTENSSQEISVEER[166.11].T sp|Q96T58|MINT_HUMAN 1 1813.8569 1.72 82208 12816 2 1813.859459 907.9357 Msx2-interacting protein OS=Homo sapiens OX=9606 GN=SPEN PE=1 SV=1 4.09 2332.7 - 457983 - - - 1.3992 - 2.961 0.608 - 580.8 1 2 0 0.0025 16 0 0 0 1.54E+07 8.93E+06 - - - 6.1997 1 221125_WJC_METTL3_EV_vs_WT_F06.12820.12820.2 6.00E-06 14/22 K.LTSDDVKEQIYK.L "sp|P62277|RS13_HUMAN,tr|J3KMX5|J3KMX5_HUMAN,tr|E9PS50|E9PS50_HUMAN" 3 1437.7351 0.99 82210 12820 2 1437.737 719.8748 40S ribosomal protein S13 OS=Homo sapiens OX=9606 GN=RPS13 PE=1 SV=2 4.56 2333.2 - 1.21E+06 - - - 1.3041 - 2.776 0.566 - 690.8 1 2 1 0.0019 12 0 0 0 2.38E+07 2.40E+07 - - - 5.9073 1 221125_WJC_METTL3_EV_vs_WT_F06.12821.12821.2 3.00E-08 28-Dec K.ENTPSEANLQEEEVR.T "sp|Q93062|RBPMS_HUMAN,tr|B4E3T4|B4E3T4_HUMAN" 2 1743.7911 1.86 82211 12821 2 1743.789998 872.9028 RNA-binding protein with multiple splicing OS=Homo sapiens OX=9606 GN=RBPMS PE=1 SV=1 3.98 2333.3 - 664065 - - - -0.6526 - 3.039 0.629 - 546.1 1 2 0 -0.0011 15 0 0 0 1.06E+07 5.71E+06 - - - 6.4192 0.9729 221125_WJC_METTL3_EV_vs_WT_F06.12824.12824.3 0.19 Oct-44 R.SGLSVSSLRPNR.K "tr|A0A087X1X7|A0A087X1X7_HUMAN,tr|H0YCK7|H0YCK7_HUMAN,tr|E9PRY8|E9PRY8_HUMAN" 3 1271.6946 1.19 82214 12824 3 1271.692488 424.9055 Elongation factor 1-delta OS=Homo sapiens OX=9606 GN=EEF1D PE=1 SV=1 12 2333.7 - 224078 - - - -1.6592 - 1.809 0.111 - 140.6 1 2 0 -0.0021 12 0 0 0 3.82E+06 3.21E+06 - - - 1.42 0.9973 221125_WJC_METTL3_EV_vs_WT_F06.12827.12827.3 2.11E-05 15/36 R.NKDPILHVLR.Q "sp|Q96S19|MTL26_HUMAN,tr|A0A087WYU2|A0A087WYU2_HUMAN,tr|H3BRT2|H3BRT2_HUMAN,tr|H3BNB2|H3BNB2_HUMAN,tr|H3BS73|H3BS73_HUMAN" 5 1203.7088 2.32 82216 12827 3 1203.71037 402.2435 Methyltransferase-like 26 OS=Homo sapiens OX=9606 GN=METTL26 PE=1 SV=2 8.75 2334.1 - 633650 - - - 1.3118 - 2.449 0.246 - 329.5 1 2 1 0.0016 10 0 0 0 1.20E+07 5.15E+06 - - - 3.898 0.9999 221125_WJC_METTL3_EV_vs_WT_F06.12828.12828.3 5.67E-07 14/40 K.LQLLEDDK[136.11]ENR[166.11].Y "sp|P09874|PARP1_HUMAN,tr|A0A7I2V3E1|A0A7I2V3E1_HUMAN" 2 1389.7219 0.12 82217 12828 3 1389.722682 464.2479 Poly [ADP-ribose] polymerase 1 OS=Homo sapiens OX=9606 GN=PARP1 PE=1 SV=4 4.32 2334.1 - 8.85E+06 - - - 0.5785 - 2.872 0.469 - 451.4 1 2 1 0.0008 11 0 0 0 1.87E+08 1.55E+09 - - - 6.7658 0.9999 221125_WJC_METTL3_EV_vs_WT_F06.12830.12830.2 6.97E-10 14/26 R.QAVTNPNNTFYATK.R "sp|P38646|GRP75_HUMAN,tr|H0Y8K0|H0Y8K0_HUMAN,tr|A0A7I2V2S7|A0A7I2V2S7_HUMAN,tr|A0A7I2V2G2|A0A7I2V2G2_HUMAN,tr|A0A3B3ITI4|A0A3B3ITI4_HUMAN,tr|A0A7I2V3F7|A0A7I2V3F7_HUMAN,tr|A0A7I2YQB2|A0A7I2YQB2_HUMAN,tr|D6RCD7|D6RCD7_HUMAN" 8 1567.7631 0.55 82219 12830 2 1567.760755 784.8888 "Stress-70 protein, mitochondrial OS=Homo sapiens OX=9606 GN=HSPA9 PE=1 SV=2" 8.59 2334.3 - 1.35E+06 - - - -1.4773 - 2.927 0.504 - 638.9 1 2 0 -0.0023 14 0 0 0 5.35E+07 9.70E+07 - - - 5.4579 1 221125_WJC_METTL3_EV_vs_WT_F06.12831.12831.3 3.56E-07 14/44 R.GESYTC[160.03]GYKPFR.C "sp|Q86UP3|ZFHX4_HUMAN,sp|Q15911|ZFHX3_HUMAN,tr|E5RI93|E5RI93_HUMAN,tr|E7EVZ1|E7EVZ1_HUMAN" 4 1463.6503 1.37 82220 12831 3 1463.650289 488.8907 Zinc finger homeobox protein 4 OS=Homo sapiens OX=9606 GN=ZFHX4 PE=1 SV=1 8.18 2334.4 - 997037 - - - -0.0417 - 2.696 0.529 - 358.2 1 2 0 -0.0001 12 0 0 0 1.25E+07 9.15E+06 - - - 7.1868 1 221125_WJC_METTL3_EV_vs_WT_F06.12832.12832.3 1.86E-08 21/60 R.IFR[166.11]EEQNGEDEDGGWR[166.11].L "sp|Q6Y7W6|GGYF2_HUMAN,tr|I1E4Y6|I1E4Y6_HUMAN,tr|A0A7I2V516|A0A7I2V516_HUMAN,tr|A0A7I2V3H0|A0A7I2V3H0_HUMAN,tr|C9JHW1|C9JHW1_HUMAN,tr|E7ESB6|E7ESB6_HUMAN" 6 1955.8513 3.13 82221 12832 3 1955.853242 652.9577 GRB10-interacting GYF protein 2 OS=Homo sapiens OX=9606 GN=GIGYF2 PE=1 SV=1 4.08 2334.5 - 961253 - - - 1.0067 - 3.859 0.608 - 688.4 1 2 1 0.002 16 0 0 0 3.63E+07 1.16E+07 - - - 8.783 0.9984 221125_WJC_METTL3_EV_vs_WT_F06.12835.12835.2 4.95E-05 26-Dec R.YESLTDPSK[136.11]LDSGK[136.11].E "sp|Q58FF8|H90B2_HUMAN,sp|P08238|HS90B_HUMAN,sp|Q58FF7|H90B3_HUMAN,sp|P07900|HS90A_HUMAN,sp|Q14568|HS902_HUMAN,tr|G3V2J8|G3V2J8_HUMAN" 6 1554.7748 0.77 82224 12835 2 1554.777183 778.3947 Putative heat shock protein HSP 90-beta 2 OS=Homo sapiens OX=9606 GN=HSP90AB2P PE=1 SV=2 4.56 2334.9 - 453587 - - - 1.5211 - 2.556 0.577 - 437.8 1 2 1 0.0024 14 0 0 0 2.39E+07 3.12E+07 - - - 5.657 0.9001 221125_WJC_METTL3_EV_vs_WT_F06.12837.12837.2 0.0357 30-Sep C.AEAGANMIVSGSAIMR[166.11].S "sp|Q96AT9|RPE_HUMAN,tr|C9J6A7|C9J6A7_HUMAN" 2 1586.7784 5.18 82226 12837 2 1586.780248 794.3965 Ribulose-phosphate 3-epimerase OS=Homo sapiens OX=9606 GN=RPE PE=1 SV=1 6.05 2335.1 - 332187 - - - 1.1539 - 1.8 0.225 - 216.4 1 1 0 0.0018 16 0 0 0 7.70E+07 1.49E+07 - - - 2.1474 0.9977 221125_WJC_METTL3_EV_vs_WT_F06.12840.12840.3 1.92E-07 Dec-48 V.RFLEQQNQVLQTK.W "sp|Q7Z794|K2C1B_HUMAN,sp|P04264|K2C1_HUMAN,sp|P35908|K22E_HUMAN" 3 1630.8791 20.04 82228 12840 3 1630.880653 544.6336 "Keratin, type II cytoskeletal 1b OS=Homo sapiens OX=9606 GN=KRT77 PE=1 SV=3" 8.75 2335.5 - 4.49E+06 - - - 0.9498 - 2.475 0.543 - 222.8 1 1 0 0.0015 13 0 0 0 4.70E+07 2.35E+06 - - - 7.0506 1 221125_WJC_METTL3_EV_vs_WT_F06.12841.12841.3 0.000105 15/48 K.QVKPLPAPLDGQR.K "sp|Q8WWY3|PRP31_HUMAN,tr|E7EVX8|E7EVX8_HUMAN" 2 1417.8041 2.59 82229 12841 3 1417.804832 473.6087 U4\U6 small nuclear ribonucleoprotein Prp31 OS=Homo sapiens OX=9606 GN=PRPF31 PE=1 SV=2 8.75 2335.5 - 2.89E+06 - - - 0.4824 - 2.37 0.535 - 391.7 1 2 0 0.0007 13 0 0 0 1.90E+08 7.36E+07 - - - 6.8441 0.9999 221125_WJC_METTL3_EV_vs_WT_F06.12842.12842.3 1.20E-05 Nov-44 R.R[166.11]FDDAVVQSDMK[136.11].H "sp|P11142|HSP7C_HUMAN,tr|E9PQQ4|E9PQQ4_HUMAN,tr|E9PNE6|E9PNE6_HUMAN,tr|E9PKE3|E9PKE3_HUMAN,tr|E9PN89|E9PN89_HUMAN,tr|E9PLF4|E9PLF4_HUMAN,tr|E9PK54|E9PK54_HUMAN,tr|E9PN25|E9PN25_HUMAN,tr|E9PPY6|E9PPY6_HUMAN,tr|E9PQK7|E9PQK7_HUMAN" 10 1427.6834 0.13 82230 12842 3 1427.687058 476.9017 Heat shock cognate 71 kDa protein OS=Homo sapiens OX=9606 GN=HSPA8 PE=1 SV=1 4.43 2335.6 - 7.98E+06 - - - 2.5734 - 2.389 0.503 - 239.8 1 2 0 0.0037 12 0 0 0 9.21E+07 7.21E+08 - - - 6.5609 0.9998 221125_WJC_METTL3_EV_vs_WT_F06.12846.12846.2 3.69E-05 15/22 R.TAAENEFVTLKK.D "sp|P48668|K2C6C_HUMAN,sp|P12035|K2C3_HUMAN,sp|P04259|K2C6B_HUMAN,sp|P02538|K2C6A_HUMAN" 4 1349.7191 999 82234 12846 2 1349.721857 675.8668 "Keratin, type II cytoskeletal 6C OS=Homo sapiens OX=9606 GN=KRT6C PE=1 SV=3" 5.81 2335.9 - 850125 - - - 2.0567 - 2.753 0.537 - 681.6 1 2 0 0.0028 12 0 0 0 6.09E+07 0.00E+00 - - - 5.671 1 221125_WJC_METTL3_EV_vs_WT_F06.12850.12850.2 1.63E-08 17/22 R.R[166.11]FDDAVVQSDMK[136.11].H "sp|P11142|HSP7C_HUMAN,tr|E9PQQ4|E9PQQ4_HUMAN,tr|E9PNE6|E9PNE6_HUMAN,tr|E9PKE3|E9PKE3_HUMAN,tr|E9PN89|E9PN89_HUMAN,tr|E9PLF4|E9PLF4_HUMAN,tr|E9PK54|E9PK54_HUMAN,tr|E9PN25|E9PN25_HUMAN,tr|E9PPY6|E9PPY6_HUMAN,tr|E9PQK7|E9PQK7_HUMAN" 10 1427.6834 0.13 82236 12850 2 1427.684662 714.849 Heat shock cognate 71 kDa protein OS=Homo sapiens OX=9606 GN=HSPA8 PE=1 SV=1 4.43 2336.4 - 4.21E+06 - - - 0.8952 - 3.626 0.669 - 1269.7 1 2 0 0.0013 12 0 0 0 3.11E+07 2.35E+08 - - - 7.3711 0.9997 221125_WJC_METTL3_EV_vs_WT_F06.12852.12852.3 0.000243 28-Nov R.R[166.11]DYLHYIR[166.11].K "sp|P62280|RS11_HUMAN,tr|M0R1H5|M0R1H5_HUMAN,tr|M0QZC5|M0QZC5_HUMAN" 3 1154.61 0.04 82238 12852 3 1154.610284 385.8773 40S ribosomal protein S11 OS=Homo sapiens OX=9606 GN=RPS11 PE=1 SV=3 8.6 2336.5 - 6.43E+06 - - - 0.2746 - 2.283 0.268 - 257 1 2 0 0.0003 8 0 0 0 4.59E+06 1.12E+08 - - - 4.1079 1 221125_WJC_METTL3_EV_vs_WT_F06.12855.12855.3 4.62E-10 17/64 R.VMLGETNPADSK[136.11]PGTIR[166.11].G "sp|O60361|NDK8_HUMAN,sp|P15531|NDKA_HUMAN,sp|P22392|NDKB_HUMAN,tr|Q32Q12|Q32Q12_HUMAN,tr|Q32Q12|Q32Q12_HUMAN,tr|J3KPD9|J3KPD9_HUMAN,tr|E7ERL0|E7ERL0_HUMAN" 7 1802.9316 1.61 82241 12855 3 1802.933589 601.9845 Putative nucleoside diphosphate kinase OS=Homo sapiens OX=9606 GN=NME2P1 PE=5 SV=1 6.04 2336.8 - 1.31E+06 - - - 1.1287 - 3.126 0.6 - 274.6 1 2 0 0.002 17 0 0 0 5.38E+07 3.34E+07 - - - 8.1082 1 221125_WJC_METTL3_EV_vs_WT_F06.12857.12857.2 7.60E-09 28-Nov K.ENTPSEANLQEEEVR[166.11].T "sp|Q93062|RBPMS_HUMAN,tr|B4E3T4|B4E3T4_HUMAN" 2 1753.7994 1.86 82243 12857 2 1753.795663 877.907 RNA-binding protein with multiple splicing OS=Homo sapiens OX=9606 GN=RBPMS PE=1 SV=1 3.98 2337 - 459289 - - - -2.1342 - 2.703 0.646 - 424.7 1 2 0 -0.0037 15 0 0 0 1.06E+07 5.71E+06 - - - 6.2559 0.9997 221125_WJC_METTL3_EV_vs_WT_F06.12858.12858.3 0.00357 13/40 R.NADLDSFTTHR.R "sp|Q8N3Y1|FBXW8_HUMAN,tr|A0A499FIY5|A0A499FIY5_HUMAN" 2 1275.5844 0.86 82244 12858 3 1275.581381 426.2021 F-box\WD repeat-containing protein 8 OS=Homo sapiens OX=9606 GN=FBXW8 PE=1 SV=2 5.21 2337.1 - 426915 - - - -2.3495 - 2.301 0.37 - 298.8 1 2 0 -0.003 11 0 0 0 6.50E+06 7.57E+06 - - - 5.0317 0.9346 221125_WJC_METTL3_EV_vs_WT_F06.12859.12859.2 0.0172 24-Oct V.RFLEQQNQVLQTK.W "sp|Q7Z794|K2C1B_HUMAN,sp|P04264|K2C1_HUMAN,sp|P35908|K22E_HUMAN" 3 1630.8791 999 82245 12859 2 1630.87342 816.4468 "Keratin, type II cytoskeletal 1b OS=Homo sapiens OX=9606 GN=KRT77 PE=1 SV=3" 8.75 2337.3 - 396149 - - - -3.4852 - 2.393 0.397 - 232.4 1 1 0 -0.0057 13 0 0 0 3.53E+06 0.00E+00 - - - 4.2109 1 221125_WJC_METTL3_EV_vs_WT_F06.12860.12860.2 1.12E-12 15/34 M.ASGGGVPTDEEQATGLER.E sp|P10606|COX5B_HUMAN 1 1772.8177 1.32 82246 12860 2 1772.821541 887.4161 "Cytochrome c oxidase subunit 5B, mitochondrial OS=Homo sapiens OX=9606 GN=COX5B PE=1 SV=2" 4 2337.4 - 382680 - - - 2.1745 - 2.994 0.609 - 359 1 1 0 0.0039 18 0 0 0 6.17E+07 4.67E+07 - - - 6.2339 0.999 221125_WJC_METTL3_EV_vs_WT_F06.12868.12868.3 0.109 Aug-36 K.EQAQPPHLWK.S sp|P31271|HXA13_HUMAN 1 1232.6302 1.78 82252 12868 3 1232.630675 411.884 Homeobox protein Hox-A13 OS=Homo sapiens OX=9606 GN=HOXA13 PE=1 SV=3 6.85 2338.3 - 2.16E+06 - - - 0.3805 - 1.614 0.302 - 98.1 1 2 0 0.0005 10 0 0 0 4.08E+07 2.29E+07 - - - 3.3049 1 221125_WJC_METTL3_EV_vs_WT_F06.12870.12870.3 0.0027 Nov-36 R.RIEFAEQINK.M sp|Q9H307|PININ_HUMAN 1 1246.667 1.81 82254 12870 3 1246.666182 416.5629 Pinin OS=Homo sapiens OX=9606 GN=PNN PE=1 SV=5 6.14 2338.4 - 1.43E+06 - - - -0.6449 - 2.273 0.454 - 195 1 2 0 -0.0008 10 0 0 0 4.47E+07 2.47E+07 - - - 5.9994 1 221125_WJC_METTL3_EV_vs_WT_F06.12871.12871.2 5.65E-05 18/22 R.RFDDAVVQSDMK.H "sp|P11142|HSP7C_HUMAN,tr|E9PQQ4|E9PQQ4_HUMAN,tr|E9PNE6|E9PNE6_HUMAN,tr|E9PKE3|E9PKE3_HUMAN,tr|E9PN89|E9PN89_HUMAN,tr|E9PLF4|E9PLF4_HUMAN,tr|E9PK54|E9PK54_HUMAN,tr|E9PN25|E9PN25_HUMAN,tr|E9PPY6|E9PPY6_HUMAN,tr|E9PQK7|E9PQK7_HUMAN" 10 1409.6609 0.13 82255 12871 2 1409.65759 705.8377 Heat shock cognate 71 kDa protein OS=Homo sapiens OX=9606 GN=HSPA8 PE=1 SV=1 4.43 2338.5 - 1.07E+06 - - - -2.358 - 3.105 0.523 - 1302.5 1 2 0 -0.0033 12 0 0 0 3.11E+07 2.35E+08 - - - 5.884 0.9999 221125_WJC_METTL3_EV_vs_WT_F06.12872.12872.3 0.000877 Dec-36 R.R[166.11]IEFAEQINK[136.11].M sp|Q9H307|PININ_HUMAN 1 1264.6895 1.83 82256 12872 3 1264.68803 422.5704 Pinin OS=Homo sapiens OX=9606 GN=PNN PE=1 SV=5 6.14 2338.6 - 934785 - - - -1.1275 - 2.387 0.378 - 277.9 1 2 0 -0.0014 10 0 0 0 4.50E+07 2.46E+07 - - - 5.2948 0.9949 221125_WJC_METTL3_EV_vs_WT_F06.12874.12874.2 2.32E-06 Dec-38 K.LVQDVANNTNEEAGDGTTTA.T "sp|P10809|CH60_HUMAN,tr|C9JL25|C9JL25_HUMAN,tr|A0A7I2V2X6|A0A7I2V2X6_HUMAN,tr|A0A7I2YQK6|A0A7I2YQK6_HUMAN,tr|A0A7I2V599|A0A7I2V599_HUMAN,tr|E7EXB4|E7EXB4_HUMAN,tr|A0A7I2YQ71|A0A7I2YQ71_HUMAN,tr|E7ESH4|E7ESH4_HUMAN,tr|A0A7I2V5M1|A0A7I2V5M1_HUMAN,tr|A0A7I2V5K3|A0A7I2V5K3_HUMAN,tr|A0A7I2V369|A0A7I2V369_HUMAN" 11 2018.9029 - 82258 12874 2 2018.902781 1010.4587 "60 kDa heat shock protein, mitochondrial OS=Homo sapiens OX=9606 GN=HSPD1 PE=1 SV=2" 3.43 2338.9 - 666356 - - - -0.0451 - 2.283 0.609 - 320.1 1 1 0 -0.0001 20 0 0 0 - - - - - 5.5686 0.9993 221125_WJC_METTL3_EV_vs_WT_F06.12875.12875.3 0.0114 Sep-36 K.NFSSLHLNSR[166.11].D sp|Q9NYL2|M3K20_HUMAN 1 1183.5973 0.93 82259 12875 3 1183.597637 395.5397 Mitogen-activated protein kinase kinase kinase 20 OS=Homo sapiens OX=9606 GN=MAP3K20 PE=1 SV=3 9.76 2339 - 295827 - - - 0.2509 - 1.692 0.316 - 117.6 1 2 0 0.0003 10 0 0 0 2.11E+06 2.26E+06 - - - 3.5989 1 221125_WJC_METTL3_EV_vs_WT_F06.12878.12878.3 1.44E-05 Oct-44 R.RFDDAVVQSDMK.H "sp|P11142|HSP7C_HUMAN,tr|E9PQQ4|E9PQQ4_HUMAN,tr|E9PNE6|E9PNE6_HUMAN,tr|E9PKE3|E9PKE3_HUMAN,tr|E9PN89|E9PN89_HUMAN,tr|E9PLF4|E9PLF4_HUMAN,tr|E9PK54|E9PK54_HUMAN,tr|E9PN25|E9PN25_HUMAN,tr|E9PPY6|E9PPY6_HUMAN,tr|E9PQK7|E9PQK7_HUMAN" 10 1409.6609 0.13 82260 12878 3 1409.659735 470.8942 Heat shock cognate 71 kDa protein OS=Homo sapiens OX=9606 GN=HSPA8 PE=1 SV=1 4.43 2339.4 - 6.81E+06 - - - -0.8364 - 2.06 0.569 - 207.7 1 2 0 -0.0012 12 0 0 0 9.21E+07 7.20E+08 - - - 6.8867 0.9999 221125_WJC_METTL3_EV_vs_WT_F06.12880.12880.3 6.27E-06 17/36 R.NNRYPNLQLR.E "sp|Q14671|PUM1_HUMAN,tr|Q5T1Z8|Q5T1Z8_HUMAN,tr|H0YDK8|H0YDK8_HUMAN,tr|H0YEH2|H0YEH2_HUMAN,tr|Q5T1Z4|Q5T1Z4_HUMAN,tr|E9PR38|E9PR38_HUMAN" 6 1286.6844 2.18 82262 12880 3 1286.684959 429.9021 Pumilio homolog 1 OS=Homo sapiens OX=9606 GN=PUM1 PE=1 SV=3 10.84 2339.5 - 3.61E+06 - - - 0.4601 - 3.284 0.506 - 683.8 1 2 1 0.0006 10 0 0 0 7.76E+08 3.55E+08 - - - 7.6538 0.9996 221125_WJC_METTL3_EV_vs_WT_F06.12882.12882.2 0.0265 18-Nov R.R[166.11]IEFAEQINK[136.11].M sp|Q9H307|PININ_HUMAN 1 1264.6895 1.86 82264 12882 2 1264.689417 633.352 Pinin OS=Homo sapiens OX=9606 GN=PNN PE=1 SV=5 6.14 2339.7 - 869824 - - - -0.0308 - 2.198 0.265 - 510 1 2 0 0 10 0 0 0 2.87E+07 1.55E+07 - - - 3.1966 0.9997 221125_WJC_METTL3_EV_vs_WT_F06.12889.12889.2 0.00456 18-Dec R.RIEFAEQINK.M sp|Q9H307|PININ_HUMAN 1 1246.667 1.87 82269 12889 2 1246.668311 624.3408 Pinin OS=Homo sapiens OX=9606 GN=PNN PE=1 SV=5 6.14 2340.7 - 1.66E+06 - - - 1.0628 - 2.345 0.352 - 614.2 1 2 0 0.0013 10 0 0 0 2.87E+07 1.54E+07 - - - 4.0194 0.9999 221125_WJC_METTL3_EV_vs_WT_F06.12891.12891.3 6.26E-06 16/60 K.AQPPEAGPQGLHDLGR[166.11].S "sp|A0FGR8|ESYT2_HUMAN,tr|A0A499FIX8|A0A499FIX8_HUMAN,tr|H7BXI1|H7BXI1_HUMAN,tr|A0A087WXU3|A0A087WXU3_HUMAN" 4 1651.8306 1.6 82271 12891 3 1651.83516 551.6175 Extended synaptotagmin-2 OS=Homo sapiens OX=9606 GN=ESYT2 PE=1 SV=1 5.32 2340.8 - 1.32E+06 - - - 2.7684 - 3.664 0.494 - 387.4 1 2 0 0.0046 16 0 0 0 2.88E+07 1.81E+07 - - - 7.3783 1 221125_WJC_METTL3_EV_vs_WT_F06.12892.12892.2 5.85E-12 15/26 R.YESLTDPSKLDSGK.E "sp|Q58FF8|H90B2_HUMAN,sp|P08238|HS90B_HUMAN,sp|Q58FF7|H90B3_HUMAN,sp|P07900|HS90A_HUMAN,sp|Q14568|HS902_HUMAN,tr|G3V2J8|G3V2J8_HUMAN" 6 1538.7464 0.77 82272 12892 2 1538.748095 770.3805 Putative heat shock protein HSP 90-beta 2 OS=Homo sapiens OX=9606 GN=HSP90AB2P PE=1 SV=2 4.56 2340.9 - 1.04E+06 - - - 1.0898 - 2.955 0.69 - 759.7 1 2 1 0.0017 14 0 0 0 2.39E+07 3.12E+07 - - - 6.8558 0.9999 221125_WJC_METTL3_EV_vs_WT_F06.12897.12897.3 9.77E-05 Dec-36 R.NNR[166.11]YPNLQLR[166.11].E "sp|Q14671|PUM1_HUMAN,tr|Q5T1Z8|Q5T1Z8_HUMAN,tr|H0YDK8|H0YDK8_HUMAN,tr|H0YEH2|H0YEH2_HUMAN,tr|Q5T1Z4|Q5T1Z4_HUMAN,tr|E9PR38|E9PR38_HUMAN" 6 1306.7009 2.18 82276 12897 3 1306.701467 436.5742 Pumilio homolog 1 OS=Homo sapiens OX=9606 GN=PUM1 PE=1 SV=3 10.84 2341.5 - 1.20E+07 - - - 0.4286 - 2.618 0.488 - 406.2 1 2 1 0.0006 10 0 0 0 7.75E+08 3.55E+08 - - - 6.7912 1 221125_WJC_METTL3_EV_vs_WT_F06.12899.12899.3 0.000214 15/52 K.IEDDNDNAPYFEHR.V sp|Q08554|DSC1_HUMAN 1 1733.7281 999 82277 12899 3 1733.728277 578.9167 Desmocollin-1 OS=Homo sapiens OX=9606 GN=DSC1 PE=1 SV=2 4.1 2341.8 - 2.77E+06 - - - 0.0779 - 2.856 0.664 - 310.3 1 2 0 0.0001 14 0 0 0 2.05E+08 0.00E+00 - - - 8.7318 0.9982 221125_WJC_METTL3_EV_vs_WT_F06.12900.12900.2 0.000667 13/18 R.NNRYPNLQLR.E "sp|Q14671|PUM1_HUMAN,tr|Q5T1Z8|Q5T1Z8_HUMAN,tr|H0YDK8|H0YDK8_HUMAN,tr|H0YEH2|H0YEH2_HUMAN,tr|Q5T1Z4|Q5T1Z4_HUMAN,tr|E9PR38|E9PR38_HUMAN" 6 1286.6844 2.2 82278 12900 2 1286.685485 644.3495 Pumilio homolog 1 OS=Homo sapiens OX=9606 GN=PUM1 PE=1 SV=3 10.84 2341.9 - 1.29E+06 - - - 0.8689 - 2.516 0.422 - 309.2 1 2 1 0.0011 10 0 0 0 5.86E+07 2.67E+07 - - - 4.733 0.9998 221125_WJC_METTL3_EV_vs_WT_F06.12901.12901.4 8.78E-05 14/96 R.VLLDHGAGINTHSNEFK.E "sp|Q8IWZ3|ANKH1_HUMAN,tr|E9PDP5|E9PDP5_HUMAN,tr|D6RHC4|D6RHC4_HUMAN" 3 1850.9275 0.96 82279 12901 4 1850.927294 463.7392 Ankyrin repeat and KH domain-containing protein 1 OS=Homo sapiens OX=9606 GN=ANKHD1 PE=1 SV=1 5.99 2342 - 1.44E+06 - - - -0.1172 - 2.122 0.388 - 95.7 1 2 0 -0.0002 17 0 0 0 1.10E+07 1.15E+07 - - - 2.8643 0.9999 221125_WJC_METTL3_EV_vs_WT_F06.12905.12905.2 2.13E-05 13/26 R.SGC[160.03]ALTDAVAPGNK[136.11].G "sp|Q9BQ70|TCF25_HUMAN,tr|H3BTU3|H3BTU3_HUMAN,tr|H3BMJ8|H3BMJ8_HUMAN,tr|Q9H7D3|Q9H7D3_HUMAN,tr|H3BS87|H3BS87_HUMAN,tr|H3BSP8|H3BSP8_HUMAN" 6 1367.6595 0.56 82283 12905 2 1367.65857 684.837 Transcription factor 25 OS=Homo sapiens OX=9606 GN=TCF25 PE=1 SV=1 5.55 2342.4 - 730397 - - - -0.6537 - 2.048 0.523 - 403.2 1 2 0 -0.0009 14 0 0 0 9.00E+06 1.62E+07 - - - 4.7025 0.9969 221125_WJC_METTL3_EV_vs_WT_F06.12906.12906.2 0.868 18-Dec R.NNR[166.11]YPNLQLR[166.11].E "sp|Q14671|PUM1_HUMAN,tr|Q5T1Z8|Q5T1Z8_HUMAN,tr|H0YDK8|H0YDK8_HUMAN,tr|H0YEH2|H0YEH2_HUMAN,tr|Q5T1Z4|Q5T1Z4_HUMAN,tr|E9PR38|E9PR38_HUMAN" 6 1306.7009 2.2 82284 12906 2 1306.699733 654.3577 Pumilio homolog 1 OS=Homo sapiens OX=9606 GN=PUM1 PE=1 SV=3 10.84 2342.5 - 694039 - - - -0.8984 - 2.327 0.33 - 253.7 1 2 1 -0.0012 10 0 0 0 5.86E+07 2.67E+07 - - - 3.8355 1 221125_WJC_METTL3_EV_vs_WT_F06.12907.12907.3 5.64E-06 13/64 R.VLLDHGAGINTHSNEFK[136.11].E "sp|Q8IWZ3|ANKH1_HUMAN,tr|E9PDP5|E9PDP5_HUMAN,tr|D6RHC4|D6RHC4_HUMAN" 3 1858.9417 0.76 82285 12907 3 1858.940114 620.6545 Ankyrin repeat and KH domain-containing protein 1 OS=Homo sapiens OX=9606 GN=ANKHD1 PE=1 SV=1 5.99 2342.7 - 634505 - - - -0.8591 - 2.644 0.457 - 158.7 1 2 0 -0.0016 17 0 0 0 4.42E+06 5.85E+06 - - - 6.091 1 221125_WJC_METTL3_EV_vs_WT_F06.12909.12909.2 1.09E-07 13/30 K.TTPNSGDVQVTEDAVR[166.11].R "sp|P35269|T2FA_HUMAN,tr|M0QXD6|M0QXD6_HUMAN" 2 1697.8096 1.07 82287 12909 2 1697.813273 849.9121 General transcription factor IIF subunit 1 OS=Homo sapiens OX=9606 GN=GTF2F1 PE=1 SV=2 4.03 2342.9 - 369844 - - - 2.1769 - 2.689 0.579 - 578.6 1 2 0 0.0037 16 0 0 0 4.34E+06 4.04E+06 - - - 5.7483 0.9999 221125_WJC_METTL3_EV_vs_WT_F06.12912.12912.3 4.57E-08 17/52 R.YESLTDPSK[136.11]LDSGK[136.11].E "sp|Q58FF8|H90B2_HUMAN,sp|P08238|HS90B_HUMAN,sp|Q58FF7|H90B3_HUMAN,sp|P07900|HS90A_HUMAN,sp|Q14568|HS902_HUMAN,tr|G3V2J8|G3V2J8_HUMAN" 6 1554.7748 0.76 82289 12912 3 1554.775291 519.2655 Putative heat shock protein HSP 90-beta 2 OS=Homo sapiens OX=9606 GN=HSP90AB2P PE=1 SV=2 4.56 2343.3 - 2.14E+07 - - - 0.3042 - 2.737 0.611 - 242 1 2 1 0.0005 14 0 0 0 2.97E+08 3.90E+08 - - - 8.0277 1 221125_WJC_METTL3_EV_vs_WT_F06.12914.12914.3 5.96E-06 14/44 K.VQISQLHQEIQR.L sp|Q8N1N4|K2C78_HUMAN 1 1477.8001 338.61 82291 12914 3 1477.800462 493.6073 "Keratin, type II cytoskeletal 78 OS=Homo sapiens OX=9606 GN=KRT78 PE=1 SV=2" 6.72 2343.4 - 8.04E+06 - - - 0.228 - 3.002 0.467 - 514.2 1 2 0 0.0003 12 0 0 0 2.75E+08 8.12E+05 - - - 6.7935 1 221125_WJC_METTL3_EV_vs_WT_F06.12915.12915.3 3.42E-06 Dec-44 K.RTNAENEFVTIK.K sp|P04264|K2C1_HUMAN 1 1420.731 2.99 82292 12915 3 1420.731626 474.5843 "Keratin, type II cytoskeletal 1 OS=Homo sapiens OX=9606 GN=KRT1 PE=1 SV=6" 6.14 2343.4 - 7.13E+06 - - - 0.4104 - 2.584 0.517 - 335.7 1 2 0 0.0006 12 0 0 0 1.20E+08 4.02E+07 - - - 6.9353 1 221125_WJC_METTL3_EV_vs_WT_F06.12917.12917.3 3.28E-05 18/60 R.RPPASDGLDLSQAAAR.T sp|Q16352|AINX_HUMAN 1 1623.8329 1.74 82294 12917 3 1623.833819 542.2849 Alpha-internexin OS=Homo sapiens OX=9606 GN=INA PE=1 SV=2 5.96 2343.5 - 1.30E+06 - - - 0.577 - 3.175 0.532 - 596.4 1 2 0 0.0009 16 0 0 0 3.62E+07 2.08E+07 - - - 7.4354 0.9998 221125_WJC_METTL3_EV_vs_WT_F06.12918.12918.2 0.000562 14/22 K.RTNAENEFVTIK.K sp|P04264|K2C1_HUMAN 1 1420.731 160.12 82295 12918 2 1420.731972 711.3728 "Keratin, type II cytoskeletal 1 OS=Homo sapiens OX=9606 GN=KRT1 PE=1 SV=6" 6.14 2343.6 - 1.04E+06 - - - 0.6539 - 2.538 0.386 - 578.2 1 2 0 0.0009 12 0 0 0 1.85E+07 1.16E+05 - - - 4.3423 1 221125_WJC_METTL3_EV_vs_WT_F06.12928.12928.2 2.67E-08 16/30 K.SSVLIAQQTDTSDPEK.V sp|P46060|RAGP1_HUMAN 1 1717.837 1.45 82305 12928 2 1717.839137 859.9258 Ran GTPase-activating protein 1 OS=Homo sapiens OX=9606 GN=RANGAP1 PE=1 SV=1 4.03 2345 - 204981 - - - 1.23 - 3.235 0.627 - 874.3 1 2 0 0.0021 16 0 0 0 3.97E+07 2.74E+07 - - - 6.5578 0.9999 221125_WJC_METTL3_EV_vs_WT_F06.12932.12932.2 0.000716 17/22 K.VQISQLHQEIQR.L sp|Q8N1N4|K2C78_HUMAN 1 1477.8001 999 82307 12932 2 1477.801408 739.9073 "Keratin, type II cytoskeletal 78 OS=Homo sapiens OX=9606 GN=KRT78 PE=1 SV=2" 6.72 2345.5 - 1.60E+06 - - - 0.8682 - 2.887 0.496 - 1037.3 1 2 0 0.0013 12 0 0 0 2.20E+07 0.00E+00 - - - 5.4937 1 221125_WJC_METTL3_EV_vs_WT_F06.12938.12938.2 2.18E-08 16/30 K.SSVLIAQQTDTSDPEK[136.11].V sp|P46060|RAGP1_HUMAN 1 1725.8512 1.45 82313 12938 2 1725.849275 863.9329 Ran GTPase-activating protein 1 OS=Homo sapiens OX=9606 GN=RANGAP1 PE=1 SV=1 4.03 2346.1 - 811039 - - - -1.1293 - 3.305 0.652 - 745 1 2 0 -0.0019 16 0 0 0 3.97E+07 2.74E+07 - - - 6.7951 1 221125_WJC_METTL3_EV_vs_WT_F06.12940.12940.2 4.67E-11 16/26 K.IEDDNDNAPYFEHR.V sp|Q08554|DSC1_HUMAN 1 1733.7281 999 82315 12940 2 1733.726885 867.8713 Desmocollin-1 OS=Homo sapiens OX=9606 GN=DSC1 PE=1 SV=2 4.1 2346.4 - 536210 - - - -0.725 - 3.333 0.73 - 719 1 2 0 -0.0013 14 0 0 0 8.23E+06 0.00E+00 - - - 7.4534 0.9999 221125_WJC_METTL3_EV_vs_WT_F06.12941.12941.2 0.000262 22-Nov R.WQYC[160.03]GAPDGSQR[166.11].A "sp|Q9GZS1|RPA49_HUMAN,tr|E7EX70|E7EX70_HUMAN" 2 1433.6022 0.43 82316 12941 2 1433.603065 717.8084 DNA-directed RNA polymerase I subunit RPA49 OS=Homo sapiens OX=9606 GN=POLR1E PE=1 SV=3 5.83 2346.5 - 521966 - - - 0.6257 - 1.783 0.609 - 329.4 1 2 0 0.0009 12 0 0 0 2.23E+06 5.21E+06 - - - 5.0604 1 221125_WJC_METTL3_EV_vs_WT_F06.12942.12942.2 7.08E-09 30-Dec K.TTPNSGDVQVTEDAVR.R "sp|P35269|T2FA_HUMAN,tr|M0QXD6|M0QXD6_HUMAN" 2 1687.8013 1.35 82317 12942 2 1687.802767 844.9079 General transcription factor IIF subunit 1 OS=Homo sapiens OX=9606 GN=GTF2F1 PE=1 SV=2 4.03 2346.7 - 459678 - - - 0.865 - 2.668 0.678 - 478.4 1 2 0 0.0015 16 0 0 0 7.65E+06 5.67E+06 - - - 6.4609 0.9986 221125_WJC_METTL3_EV_vs_WT_F06.12944.12944.3 6.25E-06 17/60 K.LK[136.11]GEATVSFDDPPSAK[136.11].A "sp|P35637|FUS_HUMAN,tr|H3BPE7|H3BPE7_HUMAN" 2 1676.8592 0.96 82318 12944 3 1676.86052 559.9603 RNA-binding protein FUS OS=Homo sapiens OX=9606 GN=FUS PE=1 SV=1 4.56 2346.9 - 3.87E+06 - - - 0.7776 - 2.915 0.262 - 277.2 1 2 1 0.0013 16 0 0 0 3.44E+07 3.59E+07 - - - 4.2058 0.9999 221125_WJC_METTL3_EV_vs_WT_F06.12946.12946.3 3.21E-05 Oct-44 R.TAAENEFVTLKK.D "sp|P48668|K2C6C_HUMAN,sp|P12035|K2C3_HUMAN,sp|P04259|K2C6B_HUMAN,sp|P02538|K2C6A_HUMAN" 4 1349.7191 758.84 82319 12946 3 1349.721812 450.9136 "Keratin, type II cytoskeletal 6C OS=Homo sapiens OX=9606 GN=KRT6C PE=1 SV=3" 5.81 2347.1 - 2.93E+06 - - - 2.0234 - 2.338 0.502 - 128.4 1 2 0 0.0027 12 0 0 0 5.04E+08 6.64E+05 - - - 6.4902 1 221125_WJC_METTL3_EV_vs_WT_F06.12947.12947.3 1.20E-07 21/64 K.K[136.11]GTGIAAQTAGIAAAAR[166.11].A sp|P82912|RT11_HUMAN 1 1544.8754 0.82 82320 12947 3 1544.875121 515.9657 "28S ribosomal protein S11, mitochondrial OS=Homo sapiens OX=9606 GN=MRPS11 PE=1 SV=2" 11 2347.2 - 1.02E+06 - - - -0.1541 - 3.81 0.539 - 512 1 2 0 -0.0002 17 0 0 0 7.68E+06 9.33E+06 - - - 7.9285 0.865 221125_WJC_METTL3_EV_vs_WT_F06.12951.12951.2 7.92 22-May R.QENFFIALGEPK.W sp|P57103|NAC3_HUMAN 1 1391.7085 2.43 82324 12951 2 1391.709085 696.8615 Sodium\calcium exchanger 3 OS=Homo sapiens OX=9606 GN=SLC8A3 PE=1 SV=2 4.53 2347.8 - 470267 - - - 0.4088 - 0.996 0.005 - 85 2 2 0 0.0006 12 0 0 0 4.40E+06 1.81E+06 - - - -1.0673 1 221125_WJC_METTL3_EV_vs_WT_F06.12955.12955.3 2.72E-06 13/52 K.LVGDFTHDQSISQK[136.11].L sp|Q92621|NU205_HUMAN 1 1581.7878 1.49 82326 12955 3 1581.789513 528.2699 Nuclear pore complex protein Nup205 OS=Homo sapiens OX=9606 GN=NUP205 PE=1 SV=3 5.21 2348.3 - 2.85E+06 - - - 1.0602 - 2.468 0.581 - 133.9 1 2 0 0.0017 14 0 0 0 3.76E+07 2.53E+07 - - - 7.4179 1 221125_WJC_METTL3_EV_vs_WT_F06.12956.12956.3 8.39E-09 16/56 K.VTATDLDEPDTLHTR.L sp|Q08554|DSC1_HUMAN 1 1682.8111 372.5 82327 12956 3 1682.812654 561.9443 Desmocollin-1 OS=Homo sapiens OX=9606 GN=DSC1 PE=1 SV=2 4.22 2348.3 - 2.51E+06 - - - 0.8973 - 3.317 0.643 - 339 1 2 0 0.0015 15 0 0 0 1.48E+08 3.97E+05 - - - 8.8372 1 221125_WJC_METTL3_EV_vs_WT_F06.12957.12957.3 1.96E-06 Dec-52 K.LVGDFTHDQSISQK.L sp|Q92621|NU205_HUMAN 1 1573.7736 1.34 82328 12957 3 1573.775489 525.5985 Nuclear pore complex protein Nup205 OS=Homo sapiens OX=9606 GN=NUP205 PE=1 SV=3 5.21 2348.4 - 3.67E+06 - - - 1.1774 - 2.454 0.548 - 145.6 1 2 0 0.0019 14 0 0 0 3.36E+07 2.51E+07 - - - 7.0349 0.9997 221125_WJC_METTL3_EV_vs_WT_F06.12960.12960.3 3.64E-06 20/64 K.SGLRQDPQSTAAATVLK.R "sp|Q8WV92|MITD1_HUMAN,tr|F8WED5|F8WED5_HUMAN,tr|B8ZZL5|B8ZZL5_HUMAN,tr|A0A1W2PP14|A0A1W2PP14_HUMAN" 4 1741.9323 1.19 82331 12960 3 1741.936775 581.6514 MIT domain-containing protein 1 OS=Homo sapiens OX=9606 GN=MITD1 PE=1 SV=1 8.46 2348.6 - 1.37E+06 - - - 2.5908 - 3.249 0.501 - 510.6 1 2 1 0.0045 17 0 0 0 1.87E+07 1.57E+07 - - - 7.1013 0.9825 221125_WJC_METTL3_EV_vs_WT_F06.12961.12961.3 5.83E-05 16/60 R.VLGTEAVQDPTKVEAH.V sp|O43395|PRPF3_HUMAN 1 1692.8683 6.1 82332 12961 3 1692.871021 565.2967 U4\U6 small nuclear ribonucleoprotein Prp3 OS=Homo sapiens OX=9606 GN=PRPF3 PE=1 SV=2 4.65 2348.7 - 1.14E+06 - - - 1.628 - 2.87 0.499 - 251.5 1 1 1 0.0028 16 0 0 0 2.01E+07 3.29E+06 - - - 6.8078 0.9978 221125_WJC_METTL3_EV_vs_WT_F06.12962.12962.3 0.0467 Nov-36 R.NNR[166.11]YPNLQLR.E "sp|Q14671|PUM1_HUMAN,tr|Q5T1Z8|Q5T1Z8_HUMAN,tr|H0YDK8|H0YDK8_HUMAN,tr|H0YEH2|H0YEH2_HUMAN,tr|Q5T1Z4|Q5T1Z4_HUMAN,tr|E9PR38|E9PR38_HUMAN" 6 1296.6926 - 82333 12962 3 1296.695573 433.2382 Pumilio homolog 1 OS=Homo sapiens OX=9606 GN=PUM1 PE=1 SV=3 10.84 2348.8 - 824862 - - - 2.2642 - 2.137 0.34 - 200 1 2 1 0.0029 10 0 0 0 - - - - - 4.5476 0.9947 221125_WJC_METTL3_EV_vs_WT_F06.12965.12965.3 0.000727 Sep-44 K.SKGPYIC[160.03]ALC[160.03]AK.E sp|P56270|MAZ_HUMAN 1 1366.6737 0.87 82336 12965 3 1366.669018 456.5652 Myc-associated zinc finger protein OS=Homo sapiens OX=9606 GN=MAZ PE=1 SV=1 8.84 2349.2 - 406014 - - - -3.4463 - 1.931 0.369 - 119.8 1 2 1 -0.0047 12 0 0 0 1.88E+07 2.16E+07 - - - 4.4767 0.9989 221125_WJC_METTL3_EV_vs_WT_F06.12966.12966.2 4.50E-05 30-Oct R.ALLVTASQC[160.03]QQPAENK.L "sp|Q01518|CAP1_HUMAN,tr|Q5T0R6|Q5T0R6_HUMAN,tr|Q5T0R3|Q5T0R3_HUMAN,tr|Q5T0R4|Q5T0R4_HUMAN,tr|Q5T0R2|Q5T0R2_HUMAN,tr|Q5T0R1|Q5T0R1_HUMAN,tr|Q5T0R7|Q5T0R7_HUMAN,tr|Q5T0R5|Q5T0R5_HUMAN,tr|Q5T0R9|Q5T0R9_HUMAN" 9 1756.8778 1.83 82337 12966 2 1756.882933 879.4462 Adenylyl cyclase-associated protein 1 OS=Homo sapiens OX=9606 GN=CAP1 PE=1 SV=5 6.04 2349.3 - 277636 - - - 2.9308 - 1.825 0.444 - 220 1 2 0 0.0052 16 0 0 0 3.82E+06 2.09E+06 - - - 3.7978 0.9985 221125_WJC_METTL3_EV_vs_WT_F06.12968.12968.2 0.0255 26-Jul R.SSFYPDGGDQETAK.T "sp|Q9NYF8|BCLF1_HUMAN,tr|H0YF00|H0YF00_HUMAN,tr|E9PKI6|E9PKI6_HUMAN,tr|A0A1W2PQ43|A0A1W2PQ43_HUMAN,tr|E9PK91|E9PK91_HUMAN,tr|E9PJA7|E9PJA7_HUMAN,tr|E9PK09|E9PK09_HUMAN,tr|E9PQN2|E9PQN2_HUMAN" 8 1500.6369 2.2 82339 12968 2 1500.636954 751.3257 Bcl-2-associated transcription factor 1 OS=Homo sapiens OX=9606 GN=BCLAF1 PE=1 SV=2 4.03 2349.6 - 234238 - - - 0.0573 - 1.039 0.391 - 82.8 1 2 0 0.0001 14 0 0 0 1.46E+07 6.64E+06 - - - 2.0249 0.9996 221125_WJC_METTL3_EV_vs_WT_F06.12969.12969.2 1.63E-05 26-Oct K.LVGDFTHDQSISQK[136.11].L sp|Q92621|NU205_HUMAN 1 1581.7878 2.5 82340 12969 2 1581.791222 791.9012 Nuclear pore complex protein Nup205 OS=Homo sapiens OX=9606 GN=NUP205 PE=1 SV=3 5.21 2349.7 - 232355 - - - 2.1406 - 1.999 0.51 - 257.9 1 2 0 0.0034 14 0 0 0 5.14E+06 2.06E+06 - - - 4.545 0.9331 221125_WJC_METTL3_EV_vs_WT_F06.12973.12973.3 6.80E-05 Oct-52 K.IK[136.11]ELTSTC[160.03]SPIISK[136.11].P sp|P34932|HSP74_HUMAN 1 1591.8826 0.06 82342 12973 3 1591.885899 531.6348 Heat shock 70 kDa protein 4 OS=Homo sapiens OX=9606 GN=HSPA4 PE=1 SV=4 8.2 2350.2 - 1.79E+06 - - - 2.0755 - 2.136 0.444 - 151.5 1 1 1 0.0033 14 0 0 0 2.96E+06 5.15E+07 - - - 5.5061 1 221125_WJC_METTL3_EV_vs_WT_F06.12975.12975.3 9.73E-08 17/72 R.EANALAAGHPAQAVAINAR.L sp|O15020|SPTN2_HUMAN 1 1843.9653 1.86 82344 12975 3 1843.967225 615.6624 "Spectrin beta chain, non-erythrocytic 2 OS=Homo sapiens OX=9606 GN=SPTBN2 PE=1 SV=3" 6.85 2350.3 - 1.30E+06 - - - 1.0477 - 3.036 0.586 - 238.1 1 2 0 0.0019 19 0 0 0 1.55E+07 8.33E+06 - - - 7.8012 1 221125_WJC_METTL3_EV_vs_WT_F06.12977.12977.3 5.40E-08 15/52 K.IHVSYQETQQMQMK.F sp|Q86UP2|KTN1_HUMAN 1 1749.8178 2.59 82346 12977 3 1749.819461 584.2799 Kinectin OS=Homo sapiens OX=9606 GN=KTN1 PE=1 SV=1 6.75 2350.6 - 920268 - - - 0.9344 - 2.797 0.561 - 416.5 1 2 0 0.0016 14 0 0 0 9.96E+06 3.84E+06 - - - 7.5275 1 221125_WJC_METTL3_EV_vs_WT_F06.12978.12978.3 3.26E-09 20/72 R.EANALAAGHPAQAVAINAR[166.11].L sp|O15020|SPTN2_HUMAN 1 1853.9736 2.02 82347 12978 3 1853.975936 618.9985 "Spectrin beta chain, non-erythrocytic 2 OS=Homo sapiens OX=9606 GN=SPTBN2 PE=1 SV=3" 6.85 2350.7 - 777711 - - - 1.28 - 3.242 0.578 - 387.6 1 2 0 0.0024 19 0 0 0 1.64E+07 8.13E+06 - - - 7.8731 0.9998 221125_WJC_METTL3_EV_vs_WT_F06.12980.12980.3 0.00357 Nov-32 R.KNYNWAITR.E sp|Q9BYN8|RT26_HUMAN 1 1164.604 1.28 82349 12980 3 1164.604716 389.2086 "28S ribosomal protein S26, mitochondrial OS=Homo sapiens OX=9606 GN=MRPS26 PE=1 SV=1" 9.99 2350.9 - 700870 - - - 0.6217 - 1.82 0.37 - 222.7 1 2 0 0.0007 9 0 0 0 2.21E+07 1.73E+07 - - - 4.4697 1 221125_WJC_METTL3_EV_vs_WT_F06.12981.12981.2 8.75E-10 17/28 Q.QAFGNSTGGFDGQAR.Q sp|Q96PK6|RBM14_HUMAN 1 1511.6753 2.06 82350 12981 2 1511.677002 756.8449 RNA-binding protein 14 OS=Homo sapiens OX=9606 GN=RBM14 PE=1 SV=2 5.84 2351.1 - 660394 - - - 1.1133 - 3.032 0.717 - 1120 1 1 0 0.0017 15 0 0 0 1.07E+07 5.17E+06 - - - 7.0633 0.9982 221125_WJC_METTL3_EV_vs_WT_F06.12982.12982.3 0.00186 Oct-36 K.AK[136.11]EFTNVYIK[136.11].N "sp|Q13310|PABP4_HUMAN,sp|P11940|PABP1_HUMAN,tr|A0A7I2V5W9|A0A7I2V5W9_HUMAN,tr|A0A7I2YQE4|A0A7I2YQE4_HUMAN,tr|A0A7I2V649|A0A7I2V649_HUMAN,tr|B1ANR0|B1ANR0_HUMAN,tr|A0A7I2V4L7|A0A7I2V4L7_HUMAN,tr|H0YCC8|H0YCC8_HUMAN,tr|H0YAR2|H0YAR2_HUMAN,tr|E7ERJ7|E7ERJ7_HUMAN,tr|A0A7I2V598|A0A7I2V598_HUMAN,tr|A0A7I2YQ88|A0A7I2YQ88_HUMAN,tr|H0Y5F5|H0Y5F5_HUMAN,tr|H0YBN4|H0YBN4_HUMAN,tr|A0A087WTT1|A0A087WTT1_HUMAN,tr|A0A7I2YQ90|A0A7I2YQ90_HUMAN,tr|A0A7I2V4N4|A0A7I2V4N4_HUMAN,tr|E7EQV3|E7EQV3_HUMAN" 18 1227.6834 2.01 82351 12982 3 1227.68521 410.2351 Polyadenylate-binding protein 4 OS=Homo sapiens OX=9606 GN=PABPC4 PE=1 SV=1 8.54 2351.2 - 654292 - - - 1.4548 - 1.827 0.357 - 112.6 1 2 1 0.0018 10 0 0 0 2.03E+07 1.01E+07 - - - 4.2798 0.9989 221125_WJC_METTL3_EV_vs_WT_F06.12983.12983.3 0.0142 Nov-32 R.K[136.11]NYNWAITR[166.11].E sp|Q9BYN8|RT26_HUMAN 1 1182.6265 1.28 82352 12983 3 1182.626669 395.2161 "28S ribosomal protein S26, mitochondrial OS=Homo sapiens OX=9606 GN=MRPS26 PE=1 SV=1" 9.99 2351.3 - 619225 - - - 0.175 - 1.823 0.258 - 271.4 1 2 0 0.0002 9 0 0 0 2.21E+07 1.73E+07 - - - 3.2261 0.7847 221125_WJC_METTL3_EV_vs_WT_F06.12984.12984.3 0.0673 Oct-40 K.KGPQSLFNAPR.G "sp|P46087|NOP2_HUMAN,tr|F5H5X6|F5H5X6_HUMAN,tr|F5GWB7|F5GWB7_HUMAN,tr|F5H709|F5H709_HUMAN" 4 1213.6568 1.53 82353 12984 3 1213.657734 405.5595 Probable 28S rRNA (cytosine(4447)-C(5))-methyltransferase OS=Homo sapiens OX=9606 GN=NOP2 PE=1 SV=2 11 2351.4 - 588702 - - - 0.8067 - 1.488 0.027 - 120.9 1 2 0 0.001 11 0 0 0 1.41E+07 9.25E+06 - - - -0.0302 0.9957 221125_WJC_METTL3_EV_vs_WT_F06.12987.12987.3 0.023 Dec-44 R.DPYC[160.03]LSYHC[160.03]ASH.L sp|Q96F45|ZN503_HUMAN 1 1508.5813 - 82356 12987 3 1508.582165 503.8677 Zinc finger protein 503 OS=Homo sapiens OX=9606 GN=ZNF503 PE=1 SV=1 5.97 2351.8 - 373047 - - - 0.584 - 1.862 0.527 - 118.5 1 1 0 0.0009 12 0 0 0 - - - - - 6.1384 0.9967 221125_WJC_METTL3_EV_vs_WT_F06.12988.12988.2 9.97E-07 26-Dec K.VQALEEANNDLENK.L sp|P35527|K1C9_HUMAN 1 1585.7584 999 82357 12988 2 1585.767894 793.8865 "Keratin, type I cytoskeletal 9 OS=Homo sapiens OX=9606 GN=KRT9 PE=1 SV=3" 4 2351.9 - 187343 - - - 5.9997 - 2.914 0.528 - 464.8 1 2 0 0.0095 14 0 0 0 2.47E+06 0.00E+00 - - - 5.6217 0.9997 221125_WJC_METTL3_EV_vs_WT_F06.12991.12991.3 8.36E-05 Dec-52 K.AQVARPGGDTIFGK.L "sp|P49773|HINT1_HUMAN,tr|H0YC49|H0YC49_HUMAN,tr|A0A6Q8PGQ8|A0A6Q8PGQ8_HUMAN,tr|D6RE99|D6RE99_HUMAN,tr|D6REP8|D6REP8_HUMAN,tr|D6RC06|D6RC06_HUMAN,tr|D6RD60|D6RD60_HUMAN" 7 1415.7521 2.32 82358 12991 3 1415.755373 472.9246 Adenosine 5'-monophosphoramidase HINT1 OS=Homo sapiens OX=9606 GN=HINT1 PE=1 SV=2 8.79 2352.4 - 5.51E+06 - - - 2.3027 - 2.133 0.399 - 222.8 1 2 0 0.0033 14 0 0 0 6.32E+07 2.72E+07 - - - 5.0007 0.9999 221125_WJC_METTL3_EV_vs_WT_F06.12992.12992.4 0.000315 17/78 R.LVLTQEQLHQLHSR.L "sp|Q14203|DCTN1_HUMAN,tr|A0A804CDA6|A0A804CDA6_HUMAN,tr|E7EX90|E7EX90_HUMAN,tr|A0A7P0Z4C3|A0A7P0Z4C3_HUMAN,tr|E7EWF7|E7EWF7_HUMAN" 5 1700.9322 1.7 82359 12992 4 1700.938021 426.2403 Dynactin subunit 1 OS=Homo sapiens OX=9606 GN=DCTN1 PE=1 SV=3 6.92 2352.5 - 1.22E+06 - - - 3.4211 - 3.091 0.537 - 272.3 1 2 0 0.0058 14 0 0 0 5.10E+08 3.00E+08 - - - 4.3091 0.9991 221125_WJC_METTL3_EV_vs_WT_F06.12994.12994.4 0.00192 Dec-96 R.VLLDHGAGINTHSNEFK[136.11].E "sp|Q8IWZ3|ANKH1_HUMAN,tr|E9PDP5|E9PDP5_HUMAN,tr|D6RHC4|D6RHC4_HUMAN" 3 1858.9417 1.52 82361 12994 4 1858.945041 465.7427 Ankyrin repeat and KH domain-containing protein 1 OS=Homo sapiens OX=9606 GN=ANKHD1 PE=1 SV=1 5.99 2352.6 - 1.71E+06 - - - 1.7913 - 2.069 0.315 - 93.4 1 2 0 0.0033 17 0 0 0 5.11E+07 3.37E+07 - - - 2.2193 1 221125_WJC_METTL3_EV_vs_WT_F06.12996.12996.3 0.000327 14/44 R.VHMFEAHSDYIR[166.11].C "sp|P35606|COPB2_HUMAN,tr|H0Y938|H0Y938_HUMAN,tr|A0A7I2V3G0|A0A7I2V3G0_HUMAN,tr|D6RBZ7|D6RBZ7_HUMAN,tr|A0A7I2V258|A0A7I2V258_HUMAN,tr|D6R997|D6R997_HUMAN,tr|D6RBT6|D6RBT6_HUMAN,tr|H0YAC7|H0YAC7_HUMAN,tr|D6RBG7|D6RBG7_HUMAN,tr|A0A7I2YQF9|A0A7I2YQF9_HUMAN,tr|D6RCL6|D6RCL6_HUMAN" 11 1513.7012 0.64 82363 12996 3 1513.70231 505.5743 Coatomer subunit beta' OS=Homo sapiens OX=9606 GN=COPB2 PE=1 SV=2 5.99 2352.7 - 934969 - - - 0.7644 - 2.779 0.583 - 208.3 1 2 0 0.0012 12 0 0 0 5.10E+06 7.93E+06 - - - 7.8726 1 221125_WJC_METTL3_EV_vs_WT_F06.12998.12998.2 2.99E-07 17/30 C.GGGGGSFGAGGGFGSR.S sp|P04264|K2C1_HUMAN 1 1283.5643 999 82365 12998 2 1283.566465 642.7894 "Keratin, type II cytoskeletal 1 OS=Homo sapiens OX=9606 GN=KRT1 PE=1 SV=6" 9.75 2353 - 792530 - - - 1.6774 - 3.271 0.575 - 796.5 1 1 0 0.0022 16 0 0 0 6.33E+06 0.00E+00 - - - 6.2009 0.997 221125_WJC_METTL3_EV_vs_WT_F06.12999.12999.3 0.0284 Sep-36 K.K[136.11]FWEPDDSTK[136.11].D "sp|Q8TB72|PUM2_HUMAN,tr|C9JE24|C9JE24_HUMAN,tr|C9JW01|C9JW01_HUMAN" 3 1267.6056 1.2 82366 12999 3 1267.605738 423.5425 Pumilio homolog 2 OS=Homo sapiens OX=9606 GN=PUM2 PE=1 SV=2 4.56 2353.1 - 521277 - - - 0.1341 - 1.755 0.213 - 127.9 1 2 0 0.0002 10 0 0 0 9.13E+06 7.60E+06 - - - 2.5573 0.9649 221125_WJC_METTL3_EV_vs_WT_F06.13002.13002.4 0.000747 13/78 R.APVRGDRDPPVLFR.H sp|P0C7X2|ZN688_HUMAN 1 1593.874 1.04 82369 13002 4 1593.877644 399.4758 Zinc finger protein 688 OS=Homo sapiens OX=9606 GN=ZNF688 PE=1 SV=1 9.55 2353.5 - 392240 - - - 2.312 - 2.514 0.216 - 79.6 1 2 2 0.0037 14 0 0 0 3.55E+06 3.42E+06 - - - 1.4406 0.9998 221125_WJC_METTL3_EV_vs_WT_F06.13006.13006.2 0.00248 15/32 R.GATVLPANTPGNVGSGK[136.11].D sp|P22059|OSBP1_HUMAN 1 1546.8195 0.86 82373 13006 2 1546.820998 774.417 Oxysterol-binding protein 1 OS=Homo sapiens OX=9606 GN=OSBP PE=1 SV=1 8.75 2354 - 210772 - - - 0.9878 - 2.42 0.48 - 549.3 1 2 0 0.0015 17 0 0 0 3.40E+06 3.97E+06 - - - 4.7586 1 221125_WJC_METTL3_EV_vs_WT_F06.13009.13009.4 1.46E-06 15/78 R.LVLTQEQLHQLHSR[166.11].L "sp|Q14203|DCTN1_HUMAN,tr|A0A804CDA6|A0A804CDA6_HUMAN,tr|E7EX90|E7EX90_HUMAN,tr|A0A7P0Z4C3|A0A7P0Z4C3_HUMAN,tr|E7EWF7|E7EWF7_HUMAN" 5 1710.9405 1.7 82374 13009 4 1710.942851 428.7424 Dynactin subunit 1 OS=Homo sapiens OX=9606 GN=DCTN1 PE=1 SV=3 6.92 2354.4 - 4.39E+06 - - - 1.3905 - 2.743 0.555 - 148.5 1 2 0 0.0024 14 0 0 0 5.08E+08 2.99E+08 - - - 4.4233 1 221125_WJC_METTL3_EV_vs_WT_F06.13010.13010.3 0.000131 17/52 R.LVLTQEQLHQLHSR.L "sp|Q14203|DCTN1_HUMAN,tr|A0A804CDA6|A0A804CDA6_HUMAN,tr|E7EX90|E7EX90_HUMAN,tr|A0A7P0Z4C3|A0A7P0Z4C3_HUMAN,tr|E7EWF7|E7EWF7_HUMAN" 5 1700.9322 1.22 82375 13010 3 1700.936283 567.9847 Dynactin subunit 1 OS=Homo sapiens OX=9606 GN=DCTN1 PE=1 SV=3 6.92 2354.4 - 4.94E+06 - - - 2.3993 - 3.106 0.567 - 406.6 1 2 0 0.0041 14 0 0 0 4.53E+08 3.71E+08 - - - 7.8722 0.9999 221125_WJC_METTL3_EV_vs_WT_F06.13012.13012.3 1.85E-08 15/52 R.LVLTQEQLHQLHSR[166.11].L "sp|Q14203|DCTN1_HUMAN,tr|A0A804CDA6|A0A804CDA6_HUMAN,tr|E7EX90|E7EX90_HUMAN,tr|A0A7P0Z4C3|A0A7P0Z4C3_HUMAN,tr|E7EWF7|E7EWF7_HUMAN" 5 1710.9405 1.7 82377 13012 3 1710.946479 571.3208 Dynactin subunit 1 OS=Homo sapiens OX=9606 GN=DCTN1 PE=1 SV=3 6.92 2354.5 - 3.23E+06 - - - 3.5109 - 2.99 0.617 - 285.4 1 2 0 0.006 14 0 0 0 4.43E+08 2.61E+08 - - - 8.328 0.9989 221125_WJC_METTL3_EV_vs_WT_F06.13014.13014.3 0.0205 Aug-36 K.KFWEPDDSTK.D "sp|Q8TB72|PUM2_HUMAN,tr|C9JE24|C9JE24_HUMAN,tr|C9JW01|C9JW01_HUMAN" 3 1251.5772 1.15 82379 13014 3 1251.580797 418.1997 Pumilio homolog 2 OS=Homo sapiens OX=9606 GN=PUM2 PE=1 SV=2 4.56 2354.8 - 638840 - - - 2.8995 - 1.862 0.344 - 101.1 1 2 0 0.0036 10 0 0 0 8.55E+06 7.41E+06 - - - 4.1897 1 221125_WJC_METTL3_EV_vs_WT_F06.13015.13015.2 9.96E-08 15/28 K.VTATDLDEPDTLHTR.L sp|Q08554|DSC1_HUMAN 1 1682.8111 999 82380 13015 2 1682.812553 842.4128 Desmocollin-1 OS=Homo sapiens OX=9606 GN=DSC1 PE=1 SV=2 4.22 2354.9 - 626501 - - - 0.8373 - 3.396 0.657 - 714.7 1 2 0 0.0014 15 0 0 0 5.93E+06 0.00E+00 - - - 6.899 1 221125_WJC_METTL3_EV_vs_WT_F06.13017.13017.3 3.45E-08 16/44 R.VHMFEAHSDYIR.C "sp|P35606|COPB2_HUMAN,tr|H0Y938|H0Y938_HUMAN,tr|A0A7I2V3G0|A0A7I2V3G0_HUMAN,tr|D6RBZ7|D6RBZ7_HUMAN,tr|A0A7I2V258|A0A7I2V258_HUMAN,tr|D6R997|D6R997_HUMAN,tr|D6RBT6|D6RBT6_HUMAN,tr|H0YAC7|H0YAC7_HUMAN,tr|D6RBG7|D6RBG7_HUMAN,tr|A0A7I2YQF9|A0A7I2YQF9_HUMAN,tr|D6RCL6|D6RCL6_HUMAN" 11 1503.6929 0.57 82382 13017 3 1503.696576 502.2382 Coatomer subunit beta' OS=Homo sapiens OX=9606 GN=COPB2 PE=1 SV=2 5.99 2355.1 - 568689 - - - 2.456 - 2.973 0.554 - 307.1 1 2 0 0.0037 12 0 0 0 4.53E+06 7.93E+06 - - - 7.7357 0.9999 221125_WJC_METTL3_EV_vs_WT_F06.13018.13018.3 3.79E-06 19/72 R.LYQGHLQEESGPPPESMPK.M "sp|Q9Y676|RT18B_HUMAN,tr|A0A0G2JIC6|A0A0G2JIC6_HUMAN" 2 2122.9994 2.47 82383 13018 3 2123.004131 708.6737 "28S ribosomal protein S18b, mitochondrial OS=Homo sapiens OX=9606 GN=MRPS18B PE=1 SV=1" 4.75 2355.2 - 515678 - - - 2.2496 - 3.207 0.419 - 439.6 1 2 0 0.0048 19 0 0 0 1.05E+07 4.25E+06 - - - 6.0731 1 221125_WJC_METTL3_EV_vs_WT_F06.13019.13019.3 1.01E-08 18/72 R.LYQGHLQEESGPPPESMPK[136.11].M "sp|Q9Y676|RT18B_HUMAN,tr|A0A0G2JIC6|A0A0G2JIC6_HUMAN" 2 2131.0136 2.59 82384 13019 3 2131.015337 711.3451 "28S ribosomal protein S18b, mitochondrial OS=Homo sapiens OX=9606 GN=MRPS18B PE=1 SV=1" 4.75 2355.4 - 471291 - - - 0.8362 - 3.77 0.581 - 407 1 2 0 0.0018 19 0 0 0 1.05E+07 4.05E+06 - - - 8.2774 0.9999 221125_WJC_METTL3_EV_vs_WT_F06.13020.13020.2 0.000164 18-Aug R.DETNYGIPQR[166.11].A "sp|P63244|RACK1_HUMAN,tr|D6RFX4|D6RFX4_HUMAN,tr|D6RFZ9|D6RFZ9_HUMAN,tr|D6RAU2|D6RAU2_HUMAN,tr|D6R9Z1|D6R9Z1_HUMAN,tr|D6R9L0|D6R9L0_HUMAN,tr|D6RHH4|D6RHH4_HUMAN,tr|D6RBD0|D6RBD0_HUMAN,tr|D6R909|D6R909_HUMAN,tr|D6RAC2|D6RAC2_HUMAN,tr|D6RGK8|D6RGK8_HUMAN,tr|E9PD14|E9PD14_HUMAN,tr|D6REE5|D6REE5_HUMAN" 13 1201.5603 1.62 82385 13020 2 1201.560468 601.7874 Receptor of activated protein C kinase 1 OS=Homo sapiens OX=9606 GN=RACK1 PE=1 SV=3 4.37 2355.5 - 437315 - - - 0.1515 - 1.941 0.492 - 242.7 1 2 0 0.0002 10 0 0 0 1.01E+07 6.23E+06 - - - 4.5261 1 221125_WJC_METTL3_EV_vs_WT_F06.13022.13022.2 1.08E-12 19/32 R.LPSAQTPNGTDYVASGK.S "sp|Q9Y520|PRC2C_HUMAN,tr|E7EPN9|E7EPN9_HUMAN,tr|H7C5N8|H7C5N8_HUMAN,tr|A0A2R8Y7F4|A0A2R8Y7F4_HUMAN,tr|A0A2R8YET2|A0A2R8YET2_HUMAN" 5 1704.8319 1.5 82387 13022 2 1704.833113 853.4232 Protein PRRC2C OS=Homo sapiens OX=9606 GN=PRRC2C PE=1 SV=4 5.83 2355.8 - 363808 - - - 0.7238 - 3.829 0.724 - 1026.1 1 2 0 0.0012 17 0 0 0 8.45E+07 5.62E+07 - - - 7.6889 1 221125_WJC_METTL3_EV_vs_WT_F06.13024.13024.2 2.48E-11 17/32 R.LPSAQTPNGTDYVASGK[136.11].S "sp|Q9Y520|PRC2C_HUMAN,tr|E7EPN9|E7EPN9_HUMAN,tr|H7C5N8|H7C5N8_HUMAN,tr|A0A2R8Y7F4|A0A2R8Y7F4_HUMAN,tr|A0A2R8YET2|A0A2R8YET2_HUMAN" 5 1712.8461 1.5 82389 13024 2 1712.851789 857.4303 Protein PRRC2C OS=Homo sapiens OX=9606 GN=PRRC2C PE=1 SV=4 5.83 2356 - 273078 - - - 3.3336 - 3.639 0.651 - 753 1 2 0 0.0057 17 0 0 0 8.45E+07 5.62E+07 - - - 7.0232 0.9986 221125_WJC_METTL3_EV_vs_WT_F06.13025.13025.2 0.00184 Dec-32 R.GATVLPANTPGNVGSGK.D sp|P22059|OSBP1_HUMAN 1 1538.8053 0.86 82390 13025 2 1538.811314 770.4099 Oxysterol-binding protein 1 OS=Homo sapiens OX=9606 GN=OSBP PE=1 SV=1 8.75 2356.2 - 256905 - - - 3.9277 - 2.415 0.434 - 308.4 1 2 0 0.006 17 0 0 0 3.40E+06 3.97E+06 - - - 4.4123 0.9966 221125_WJC_METTL3_EV_vs_WT_F06.13027.13027.3 2.27E-05 16/44 V.LTQEQLHQLHSR.L "sp|Q14203|DCTN1_HUMAN,tr|A0A804CDA6|A0A804CDA6_HUMAN,tr|E7EX90|E7EX90_HUMAN,tr|A0A7P0Z4C3|A0A7P0Z4C3_HUMAN,tr|E7EWF7|E7EWF7_HUMAN" 5 1488.7797 1.02 82391 13027 3 1488.781266 497.2672 Dynactin subunit 1 OS=Homo sapiens OX=9606 GN=DCTN1 PE=1 SV=3 6.92 2356.5 - 1.12E+06 - - - 1.0357 - 3.186 0.431 - 656 1 1 0 0.0015 12 0 0 0 3.20E+07 3.15E+07 - - - 6.5567 0.9999 221125_WJC_METTL3_EV_vs_WT_F06.13029.13029.3 5.40E-06 Dec-40 K.AEDK[136.11]EWMPVTK[136.11].L "sp|P15880|RS2_HUMAN,tr|E9PQD7|E9PQD7_HUMAN,tr|E9PPT0|E9PPT0_HUMAN,tr|E9PMM9|E9PMM9_HUMAN" 4 1348.6668 1.05 82392 13029 3 1348.666898 450.5629 40S ribosomal protein S2 OS=Homo sapiens OX=9606 GN=RPS2 PE=1 SV=2 4.68 2356.7 - 7.52E+06 - - - 0.0816 - 2.329 0.532 - 292.4 1 2 1 0.0001 11 0 0 0 7.58E+07 7.23E+07 - - - 6.873 0.9999 221125_WJC_METTL3_EV_vs_WT_F06.13030.13030.3 1.29E-06 18/48 R.VSISEGDDK[136.11]IEYR[166.11].A "sp|P22087|FBRL_HUMAN,tr|M0R299|M0R299_HUMAN,tr|M0R0P1|M0R0P1_HUMAN,tr|M0R1H0|M0R1H0_HUMAN,tr|M0QXL5|M0QXL5_HUMAN,tr|M0R2Q4|M0R2Q4_HUMAN,tr|M0R2B0|M0R2B0_HUMAN,tr|M0R2U2|M0R2U2_HUMAN" 8 1527.7536 0.91 82393 13030 3 1527.753372 510.2585 rRNA 2'-O-methyltransferase fibrillarin OS=Homo sapiens OX=9606 GN=FBL PE=1 SV=2 4.32 2356.7 - 4.32E+06 - - - -0.1309 - 3.199 0.518 - 622.2 1 2 1 -0.0002 13 0 0 0 6.74E+08 7.38E+08 - - - 7.4679 1 221125_WJC_METTL3_EV_vs_WT_F06.13031.13031.3 8.89E-12 21/64 R.VLLDHGAGINTHSNEFK.E "sp|Q8IWZ3|ANKH1_HUMAN,tr|E9PDP5|E9PDP5_HUMAN,tr|D6RHC4|D6RHC4_HUMAN" 3 1850.9275 1.21 82394 13031 3 1850.927872 617.9831 Ankyrin repeat and KH domain-containing protein 1 OS=Homo sapiens OX=9606 GN=ANKHD1 PE=1 SV=1 5.99 2356.8 - 3.32E+06 - - - 0.195 - 4.144 0.699 - 567.9 1 2 0 0.0004 17 0 0 0 2.67E+07 2.21E+07 - - - 9.9246 0.9985 221125_WJC_METTL3_EV_vs_WT_F06.13032.13032.3 0.0012 Dec-60 K.LKGEATVSFDDPPSAK.A "sp|P35637|FUS_HUMAN,tr|H3BPE7|H3BPE7_HUMAN" 2 1660.8308 1.18 82395 13032 3 1660.831306 554.6175 RNA-binding protein FUS OS=Homo sapiens OX=9606 GN=FUS PE=1 SV=1 4.56 2356.8 - 2.62E+06 - - - 0.295 - 1.975 0.345 - 123.9 1 2 1 0.0005 16 0 0 0 4.25E+07 3.60E+07 - - - 4.1325 0.9933 221125_WJC_METTL3_EV_vs_WT_F06.13033.13033.3 0.0291 Sep-44 R.DYQDNK[136.11]ADVILK[136.11].Y "sp|O14602|IF1AY_HUMAN,sp|P47813|IF1AX_HUMAN,tr|X6RAC9|X6RAC9_HUMAN" 3 1436.7482 0.77 82396 13033 3 1436.747938 479.9233 "Eukaryotic translation initiation factor 1A, Y-chromosomal OS=Homo sapiens OX=9606 GN=EIF1AY PE=1 SV=4" 4.43 2356.9 - 2.55E+06 - - - -0.1886 - 1.615 0.285 - 80.5 1 2 1 -0.0003 12 0 0 0 1.65E+08 2.15E+08 - - - 3.046 1 221125_WJC_METTL3_EV_vs_WT_F06.13034.13034.3 1.01E-07 17/44 K.YNQATQTFHQWR.D "sp|Q8N8S7|ENAH_HUMAN,tr|A0A0U1RQP7|A0A0U1RQP7_HUMAN,tr|A0A075B6E5|A0A075B6E5_HUMAN,tr|A0A0U1RRM6|A0A0U1RRM6_HUMAN" 4 1578.7328 1.15 82397 13034 3 1578.733513 527.2515 Protein enabled homolog OS=Homo sapiens OX=9606 GN=ENAH PE=1 SV=2 8.75 2356.9 - 2.22E+06 - - - 0.4681 - 3.344 0.49 - 330.7 1 2 0 0.0007 12 0 0 0 5.43E+07 4.73E+07 - - - 7.3489 0.9999 221125_WJC_METTL3_EV_vs_WT_F06.13037.13037.3 0.000796 Dec-48 K.IESPHPVDWNDTK[136.11].S "sp|Q9H2U1|DHX36_HUMAN,tr|A0A0G2JQU7|A0A0G2JQU7_HUMAN" 2 1544.7351 1.33 82400 13037 3 1544.733633 515.919 ATP-dependent DNA\RNA helicase DHX36 OS=Homo sapiens OX=9606 GN=DHX36 PE=1 SV=2 4.54 2357.2 - 1.33E+06 - - - -0.9316 - 2.19 0.39 - 173.7 1 2 0 -0.0014 13 0 0 0 1.04E+08 7.80E+07 - - - 5.0131 0.9981 221125_WJC_METTL3_EV_vs_WT_F06.13040.13040.2 0.000419 20-Oct K.AEDK[136.11]EWMPVTK[136.11].L "sp|P15880|RS2_HUMAN,tr|E9PQD7|E9PQD7_HUMAN,tr|E9PPT0|E9PPT0_HUMAN,tr|E9PMM9|E9PMM9_HUMAN" 4 1348.6668 0.74 82403 13040 2 1348.665789 675.3407 40S ribosomal protein S2 OS=Homo sapiens OX=9606 GN=RPS2 PE=1 SV=2 4.68 2357.6 - 707583 - - - -0.7407 - 1.925 0.494 - 357.4 1 2 1 -0.001 11 0 0 0 7.46E+06 1.01E+07 - - - 4.4611 0.9999 221125_WJC_METTL3_EV_vs_WT_F06.13042.13042.2 2.60E-09 28-Dec K.ENVNATENC[160.03]ISAVGK[136.11].L "sp|O00410|IPO5_HUMAN,tr|H0Y8C6|H0Y8C6_HUMAN" 2 1612.7606 1.16 82405 13042 2 1612.762301 807.3876 Importin-5 OS=Homo sapiens OX=9606 GN=IPO5 PE=1 SV=4 4.53 2357.8 - 605680 - - - 1.033 - 2.641 0.567 - 484.6 1 2 0 0.0017 15 0 0 0 5.87E+06 5.06E+06 - - - 5.616 1 221125_WJC_METTL3_EV_vs_WT_F06.13045.13045.2 1.56E-09 14/34 M.ASGGGVPTDEEQATGLER[166.11].E sp|P10606|COX5B_HUMAN 1 1782.826 1.6 82407 13045 2 1782.826342 892.4203 "Cytochrome c oxidase subunit 5B, mitochondrial OS=Homo sapiens OX=9606 GN=COX5B PE=1 SV=2" 4 2358.2 - 565425 - - - 0.2165 - 2.751 0.65 - 262.6 1 1 0 0.0004 18 0 0 0 1.03E+07 6.47E+06 - - - 6.3297 0.9998 221125_WJC_METTL3_EV_vs_WT_F06.13047.13047.3 3.18E-05 18/52 K.GGVVLK[136.11]EDALPGQK[136.11].T "sp|P35613|BASI_HUMAN,tr|A0A7P0TA85|A0A7P0TA85_HUMAN,tr|A0A7P0TB04|A0A7P0TB04_HUMAN,tr|A0A2R8YDZ0|A0A2R8YDZ0_HUMAN,tr|I3L192|I3L192_HUMAN" 5 1425.8162 0.93 82408 13047 3 1425.812458 476.2794 Basigin OS=Homo sapiens OX=9606 GN=BSG PE=1 SV=2 6.07 2358.4 - 4.94E+06 - - - -2.6448 - 3.342 0.523 - 385.5 1 2 1 -0.0038 14 0 0 0 5.75E+07 6.17E+07 - - - 7.5764 0.9999 221125_WJC_METTL3_EV_vs_WT_F06.13048.13048.3 1.48E-06 20/52 K.GGVVLKEDALPGQK.T "sp|P35613|BASI_HUMAN,tr|A0A7P0TA85|A0A7P0TA85_HUMAN,tr|A0A7P0TB04|A0A7P0TB04_HUMAN,tr|A0A2R8YDZ0|A0A2R8YDZ0_HUMAN,tr|I3L192|I3L192_HUMAN" 5 1409.7878 0.96 82409 13048 3 1409.784155 470.9366 Basigin OS=Homo sapiens OX=9606 GN=BSG PE=1 SV=2 6.07 2358.5 - 3.59E+06 - - - -2.6061 - 3.588 0.546 - 522.4 1 2 1 -0.0037 14 0 0 0 5.95E+07 6.16E+07 - - - 8.0216 1 221125_WJC_METTL3_EV_vs_WT_F06.13052.13052.2 1.31E-06 16/20 L.TQEQLHQLHSR.L "sp|Q14203|DCTN1_HUMAN,tr|A0A804CDA6|A0A804CDA6_HUMAN,tr|E7EX90|E7EX90_HUMAN,tr|A0A7P0Z4C3|A0A7P0Z4C3_HUMAN,tr|E7EWF7|E7EWF7_HUMAN" 5 1375.6957 4.16 82413 13052 2 1375.693195 688.8551 Dynactin subunit 1 OS=Homo sapiens OX=9606 GN=DCTN1 PE=1 SV=3 6.61 2358.9 - 954902 - - - -1.7918 - 3.13 0.605 - 1467.7 1 1 0 -0.0025 11 0 0 0 1.04E+07 2.50E+06 - - - 6.5955 1 221125_WJC_METTL3_EV_vs_WT_F06.13053.13053.2 1.10E-08 17/36 R.VQDLSAGGQGSLTDSGPER[166.11].R sp|P40222|TXLNA_HUMAN 1 1882.8896 1.53 82414 13053 2 1882.886553 942.4521 Alpha-taxilin OS=Homo sapiens OX=9606 GN=TXLNA PE=1 SV=3 4.03 2359 - 906180 - - - -1.6283 - 3.481 0.678 - 745.3 1 2 0 -0.0031 19 0 0 0 1.30E+07 8.48E+06 - - - 7.1143 1 221125_WJC_METTL3_EV_vs_WT_F06.13055.13055.2 2.97E-11 15/28 K.YSASYDSYSESSGYK.N "sp|Q5VT06|CE350_HUMAN,tr|H0Y6Q4|H0Y6Q4_HUMAN" 2 1692.6791 9.22 82416 13055 2 1692.678752 847.3468 Centrosome-associated protein 350 OS=Homo sapiens OX=9606 GN=CEP350 PE=1 SV=1 4.37 2359.3 - 701092 - - - -0.221 - 3.148 0.733 - 611.6 1 2 0 -0.0004 15 0 0 0 1.11E+07 1.20E+06 - - - 7.2742 1 221125_WJC_METTL3_EV_vs_WT_F06.13056.13056.2 7.55E-08 17/24 R.VSISEGDDKIEYR.A "sp|P22087|FBRL_HUMAN,tr|M0R299|M0R299_HUMAN,tr|M0R0P1|M0R0P1_HUMAN,tr|M0R1H0|M0R1H0_HUMAN,tr|M0QXL5|M0QXL5_HUMAN,tr|M0R2Q4|M0R2Q4_HUMAN,tr|M0R2B0|M0R2B0_HUMAN,tr|M0R2U2|M0R2U2_HUMAN" 8 1509.7311 0.93 82417 13056 2 1509.729246 755.8728 rRNA 2'-O-methyltransferase fibrillarin OS=Homo sapiens OX=9606 GN=FBL PE=1 SV=2 4.32 2359.4 - 654844 - - - -1.2294 - 2.987 0.602 - 1087 1 2 1 -0.0019 13 0 0 0 6.91E+07 7.44E+07 - - - 6.2953 1 221125_WJC_METTL3_EV_vs_WT_F06.13057.13057.2 8.39E-12 17/36 R.VQDLSAGGQGSLTDSGPER.R sp|P40222|TXLNA_HUMAN 1 1872.8813 1.53 82418 13057 2 1872.882289 937.448 Alpha-taxilin OS=Homo sapiens OX=9606 GN=TXLNA PE=1 SV=3 4.03 2359.6 - 628315 - - - 0.5024 - 3.378 0.69 - 684.3 1 2 0 0.0009 19 0 0 0 1.30E+07 8.48E+06 - - - 7.1298 1 221125_WJC_METTL3_EV_vs_WT_F06.13061.13061.2 8.36E-05 16/24 R.VSISEGDDK[136.11]IEYR[166.11].A "sp|P22087|FBRL_HUMAN,tr|M0R299|M0R299_HUMAN,tr|M0R0P1|M0R0P1_HUMAN,tr|M0R1H0|M0R1H0_HUMAN,tr|M0QXL5|M0QXL5_HUMAN,tr|M0R2Q4|M0R2Q4_HUMAN,tr|M0R2B0|M0R2B0_HUMAN,tr|M0R2U2|M0R2U2_HUMAN" 8 1527.7536 0.93 82420 13061 2 1527.75071 764.8841 rRNA 2'-O-methyltransferase fibrillarin OS=Homo sapiens OX=9606 GN=FBL PE=1 SV=2 4.32 2360.1 - 3.27E+06 - - - -1.8733 - 2.963 0.603 - 1006.8 1 2 1 -0.0029 13 0 0 0 6.91E+07 7.44E+07 - - - 6.2816 0.9943 221125_WJC_METTL3_EV_vs_WT_F06.13065.13065.3 9.78E-06 14/44 V.LTQEQLHQLHSR[166.11].L "sp|Q14203|DCTN1_HUMAN,tr|A0A804CDA6|A0A804CDA6_HUMAN,tr|E7EX90|E7EX90_HUMAN,tr|A0A7P0Z4C3|A0A7P0Z4C3_HUMAN,tr|E7EWF7|E7EWF7_HUMAN" 5 1498.788 1.38 82424 13065 3 1498.789627 500.6033 Dynactin subunit 1 OS=Homo sapiens OX=9606 GN=DCTN1 PE=1 SV=3 6.92 2360.5 - 1.56E+06 - - - 1.0895 - 2.882 0.403 - 503.3 1 1 0 0.0016 12 0 0 0 2.63E+07 1.90E+07 - - - 5.9666 1 221125_WJC_METTL3_EV_vs_WT_F06.13072.13072.3 0.00098 17/36 K.R[166.11]LHVSNIPFR[166.11].F "sp|O43251|RFOX2_HUMAN,sp|Q9NWB1|RFOX1_HUMAN,sp|A6NFN3|RFOX3_HUMAN,tr|A0A6Q8PGE0|A0A6Q8PGE0_HUMAN,tr|A0A6Q8PH77|A0A6Q8PH77_HUMAN,tr|A0A286YEU2|A0A286YEU2_HUMAN,tr|A0A087X2B1|A0A087X2B1_HUMAN,tr|F8VR27|F8VR27_HUMAN,tr|B7Z1U7|B7Z1U7_HUMAN,tr|B0QYY6|B0QYY6_HUMAN,tr|B0QYV1|B0QYV1_HUMAN,tr|A0A6Q8PHA3|A0A6Q8PHA3_HUMAN,tr|A0A3B3ITL7|A0A3B3ITL7_HUMAN,tr|F8VZY7|F8VZY7_HUMAN,tr|B0QYY4|B0QYY4_HUMAN,tr|J3KNW3|J3KNW3_HUMAN,tr|F8VZG9|F8VZG9_HUMAN,tr|J3QRF4|J3QRF4_HUMAN,tr|F8VRS4|F8VRS4_HUMAN,tr|A0A6Q8PFM4|A0A6Q8PFM4_HUMAN,tr|S4R469|S4R469_HUMAN,tr|A0A804HKG7|A0A804HKG7_HUMAN,tr|A0A0G2JRA5|A0A0G2JRA5_HUMAN,tr|A0A804HJM2|A0A804HJM2_HUMAN,tr|J3QQZ2|J3QQZ2_HUMAN,tr|I3L1D4|I3L1D4_HUMAN,tr|B0QYY7|B0QYY7_HUMAN,tr|A0A0G2JSB3|A0A0G2JSB3_HUMAN" 28 1257.7209 1.1 82429 13072 3 1257.719203 420.2476 RNA binding protein fox-1 homolog 2 OS=Homo sapiens OX=9606 GN=RBFOX2 PE=1 SV=3 12 2361.4 - 3.60E+06 - - - -1.3604 - 3.262 0.439 - 728.6 1 2 0 -0.0017 10 0 0 0 3.03E+09 2.74E+09 - - - 6.8869 0.9997 221125_WJC_METTL3_EV_vs_WT_F06.13074.13074.3 0.00282 16/36 K.RLHVSNIPFR.F "sp|O43251|RFOX2_HUMAN,sp|Q9NWB1|RFOX1_HUMAN,sp|A6NFN3|RFOX3_HUMAN,tr|A0A6Q8PGE0|A0A6Q8PGE0_HUMAN,tr|A0A6Q8PH77|A0A6Q8PH77_HUMAN,tr|A0A286YEU2|A0A286YEU2_HUMAN,tr|A0A087X2B1|A0A087X2B1_HUMAN,tr|F8VR27|F8VR27_HUMAN,tr|B7Z1U7|B7Z1U7_HUMAN,tr|B0QYY6|B0QYY6_HUMAN,tr|B0QYV1|B0QYV1_HUMAN,tr|A0A6Q8PHA3|A0A6Q8PHA3_HUMAN,tr|A0A3B3ITL7|A0A3B3ITL7_HUMAN,tr|F8VZY7|F8VZY7_HUMAN,tr|B0QYY4|B0QYY4_HUMAN,tr|J3KNW3|J3KNW3_HUMAN,tr|F8VZG9|F8VZG9_HUMAN,tr|J3QRF4|J3QRF4_HUMAN,tr|F8VRS4|F8VRS4_HUMAN,tr|A0A6Q8PFM4|A0A6Q8PFM4_HUMAN,tr|S4R469|S4R469_HUMAN,tr|A0A804HKG7|A0A804HKG7_HUMAN,tr|A0A0G2JRA5|A0A0G2JRA5_HUMAN,tr|A0A804HJM2|A0A804HJM2_HUMAN,tr|J3QQZ2|J3QQZ2_HUMAN,tr|I3L1D4|I3L1D4_HUMAN,tr|B0QYY7|B0QYY7_HUMAN,tr|A0A0G2JSB3|A0A0G2JSB3_HUMAN" 28 1237.7044 1.1 82431 13074 3 1237.702133 413.5754 RNA binding protein fox-1 homolog 2 OS=Homo sapiens OX=9606 GN=RBFOX2 PE=1 SV=3 12 2361.5 - 3.25E+06 - - - -1.8106 - 2.15 0.346 - 308.3 1 2 0 -0.0022 10 0 0 0 3.03E+09 2.74E+09 - - - 4.6324 1 221125_WJC_METTL3_EV_vs_WT_F06.13075.13075.3 3.28E-06 16/56 K.EVESMGAHLNAYSTR.E sp|P31930|QCR1_HUMAN 1 1663.7624 0.86 82432 13075 3 1663.759803 555.5947 "Cytochrome b-c1 complex subunit 1, mitochondrial OS=Homo sapiens OX=9606 GN=UQCRC1 PE=1 SV=3" 5.4 2361.5 - 2.68E+06 - - - -1.5723 - 2.623 0.548 - 309 1 2 0 -0.0026 15 0 0 0 3.53E+07 4.10E+07 - - - 7.1652 1 221125_WJC_METTL3_EV_vs_WT_F06.13078.13078.2 2.12E-09 15/28 R.EDQSILC[160.03]TGESGAGK[136.11].T "sp|Q7Z406|MYH14_HUMAN,sp|P35580|MYH10_HUMAN,sp|P35749|MYH11_HUMAN,sp|P35579|MYH9_HUMAN,tr|Q5BKV1|Q5BKV1_HUMAN,tr|E7ERA5|E7ERA5_HUMAN,tr|A0A2R8Y4C3|A0A2R8Y4C3_HUMAN,tr|M0QY43|M0QY43_HUMAN,tr|A0A494C024|A0A494C024_HUMAN" 9 1558.7025 0.92 82435 13078 2 1558.703149 780.3585 Myosin-14 OS=Homo sapiens OX=9606 GN=MYH14 PE=1 SV=2 4.14 2361.8 - 1.36E+06 - - - 0.4472 - 2.838 0.67 - 747.3 1 2 0 0.0007 15 0 0 0 1.10E+08 1.20E+08 - - - 6.5539 0.9999 221125_WJC_METTL3_EV_vs_WT_F06.13084.13084.3 0.00125 Nov-44 K.YSHEVLSEENFK[136.11].V "sp|Q7Z2W4|ZCCHV_HUMAN,tr|C9J6P4|C9J6P4_HUMAN" 2 1488.6976 1.13 82439 13084 3 1488.697153 497.2398 Zinc finger CCCH-type antiviral protein 1 OS=Homo sapiens OX=9606 GN=ZC3HAV1 PE=1 SV=3 4.75 2362.6 - 2.59E+06 - - - -0.3164 - 2.044 0.41 - 247.5 1 2 0 -0.0005 12 0 0 0 2.92E+07 2.58E+07 - - - 5.0926 0.995 221125_WJC_METTL3_EV_vs_WT_F06.13086.13086.2 0.00078 15/22 F.SGSGSGTDFTLK.L "sp|A2NJV5|KV229_HUMAN,sp|A0A087WW87|KV240_HUMAN,sp|P06310|KV230_HUMAN,sp|A0A075B6S2|KVD29_HUMAN,sp|P01614|KVD40_HUMAN,sp|P01615|KVD28_HUMAN,sp|A0A075B6S6|KVD30_HUMAN,sp|A0A075B6P5|KV228_HUMAN,sp|A0A0A0MRZ7|KVD26_HUMAN" 9 1155.5408 999 82441 13086 2 1155.540801 578.7777 Immunoglobulin kappa variable 2-29 OS=Homo sapiens OX=9606 GN=IGKV2-29 PE=3 SV=2 5.55 2362.9 - 2.22E+06 - - - 0.0164 - 2.815 0.526 - 905.3 1 1 0 0 12 0 0 0 2.32E+08 0.00E+00 - - - 5.6492 1 221125_WJC_METTL3_EV_vs_WT_F06.13088.13088.2 1.90E-11 17/28 R.EDQSILC[160.03]TGESGAGK.T "sp|Q7Z406|MYH14_HUMAN,sp|P35580|MYH10_HUMAN,sp|P35749|MYH11_HUMAN,sp|P35579|MYH9_HUMAN,tr|Q5BKV1|Q5BKV1_HUMAN,tr|E7ERA5|E7ERA5_HUMAN,tr|A0A2R8Y4C3|A0A2R8Y4C3_HUMAN,tr|M0QY43|M0QY43_HUMAN,tr|A0A494C024|A0A494C024_HUMAN" 9 1550.6883 0.92 82443 13088 2 1550.685954 776.3514 Myosin-14 OS=Homo sapiens OX=9606 GN=MYH14 PE=1 SV=2 4.14 2363.1 - 2.04E+06 - - - -1.4819 - 3.119 0.612 - 1030.6 1 2 0 -0.0023 15 0 0 0 1.10E+08 1.20E+08 - - - 6.3571 1 221125_WJC_METTL3_EV_vs_WT_F06.13090.13090.3 2.46E-09 25/68 K.IWDPTPSHTPAGAATPGR.G sp|O75533|SF3B1_HUMAN 1 1830.9013 1.29 82445 13090 3 1830.900659 611.3077 Splicing factor 3B subunit 1 OS=Homo sapiens OX=9606 GN=SF3B1 PE=1 SV=3 6.74 2363.4 - 1.78E+06 - - - -0.3479 - 4.024 0.612 - 648.9 1 2 0 -0.0006 18 0 0 0 1.56E+08 1.21E+08 - - - 8.8299 0.9994 221125_WJC_METTL3_EV_vs_WT_F06.13097.13097.3 0.00118 Oct-56 K.DVDSAYMNKVELQAK.V sp|P12035|K2C3_HUMAN 1 1709.8294 999 82450 13097 3 1709.828804 570.9504 "Keratin, type II cytoskeletal 3 OS=Homo sapiens OX=9606 GN=KRT3 PE=1 SV=3" 4.56 2364.3 - 1.14E+07 - - - -0.3696 - 1.737 0.446 - 63.9 1 2 1 -0.0006 15 0 0 0 2.84E+08 0.00E+00 - - - 4.9531 0.9999 221125_WJC_METTL3_EV_vs_WT_F06.13100.13100.3 0.00011 Oct-48 K.IESPHPVDWNDTK.S "sp|Q9H2U1|DHX36_HUMAN,tr|A0A0G2JQU7|A0A0G2JQU7_HUMAN" 2 1536.7209 1.24 82453 13100 3 1536.721545 513.2476 ATP-dependent DNA\RNA helicase DHX36 OS=Homo sapiens OX=9606 GN=DHX36 PE=1 SV=2 4.54 2364.4 - 3.55E+06 - - - 0.4379 - 2.122 0.465 - 130.8 1 2 0 0.0007 13 0 0 0 1.12E+08 9.01E+07 - - - 5.764 1 221125_WJC_METTL3_EV_vs_WT_F06.13102.13102.3 1.68E-05 13/48 K.EIYTHFTC[160.03]ATDTK[136.11].N "sp|P63096|GNAI1_HUMAN,sp|P04899|GNAI2_HUMAN,sp|P08754|GNAI3_HUMAN" 3 1593.7225 1.06 82455 13102 3 1593.721119 532.2481 Guanine nucleotide-binding protein G(i) subunit alpha-1 OS=Homo sapiens OX=9606 GN=GNAI1 PE=1 SV=2 5.32 2364.6 - 1.91E+06 - - - -0.8408 - 2.301 0.489 - 174.5 1 2 0 -0.0013 13 0 0 0 4.55E+07 4.31E+07 - - - 6.2509 0.9994 221125_WJC_METTL3_EV_vs_WT_F06.13105.13105.2 0.000386 13/18 K.RLHVSNIPFR.F "sp|O43251|RFOX2_HUMAN,sp|Q9NWB1|RFOX1_HUMAN,sp|A6NFN3|RFOX3_HUMAN,tr|A0A6Q8PGE0|A0A6Q8PGE0_HUMAN,tr|A0A6Q8PH77|A0A6Q8PH77_HUMAN,tr|A0A286YEU2|A0A286YEU2_HUMAN,tr|A0A087X2B1|A0A087X2B1_HUMAN,tr|F8VR27|F8VR27_HUMAN,tr|B7Z1U7|B7Z1U7_HUMAN,tr|B0QYY6|B0QYY6_HUMAN,tr|B0QYV1|B0QYV1_HUMAN,tr|A0A6Q8PHA3|A0A6Q8PHA3_HUMAN,tr|A0A3B3ITL7|A0A3B3ITL7_HUMAN,tr|F8VZY7|F8VZY7_HUMAN,tr|B0QYY4|B0QYY4_HUMAN,tr|J3KNW3|J3KNW3_HUMAN,tr|F8VZG9|F8VZG9_HUMAN,tr|J3QRF4|J3QRF4_HUMAN,tr|F8VRS4|F8VRS4_HUMAN,tr|A0A6Q8PFM4|A0A6Q8PFM4_HUMAN,tr|S4R469|S4R469_HUMAN,tr|A0A804HKG7|A0A804HKG7_HUMAN,tr|A0A0G2JRA5|A0A0G2JRA5_HUMAN,tr|A0A804HJM2|A0A804HJM2_HUMAN,tr|J3QQZ2|J3QQZ2_HUMAN,tr|I3L1D4|I3L1D4_HUMAN,tr|B0QYY7|B0QYY7_HUMAN,tr|A0A0G2JSB3|A0A0G2JSB3_HUMAN" 28 1237.7044 1.15 82458 13105 2 1237.700611 619.8595 RNA binding protein fox-1 homolog 2 OS=Homo sapiens OX=9606 GN=RBFOX2 PE=1 SV=3 12 2365 - 1.10E+06 - - - -3.0403 - 2.325 0.449 - 251.4 1 2 0 -0.0038 10 0 0 0 1.20E+08 1.04E+08 - - - 4.7112 0.9996 221125_WJC_METTL3_EV_vs_WT_F06.13106.13106.2 8.87E-05 13/18 K.R[166.11]LHVSNIPFR[166.11].F "sp|O43251|RFOX2_HUMAN,sp|Q9NWB1|RFOX1_HUMAN,sp|A6NFN3|RFOX3_HUMAN,tr|A0A6Q8PGE0|A0A6Q8PGE0_HUMAN,tr|A0A6Q8PH77|A0A6Q8PH77_HUMAN,tr|A0A286YEU2|A0A286YEU2_HUMAN,tr|A0A087X2B1|A0A087X2B1_HUMAN,tr|F8VR27|F8VR27_HUMAN,tr|B7Z1U7|B7Z1U7_HUMAN,tr|B0QYY6|B0QYY6_HUMAN,tr|B0QYV1|B0QYV1_HUMAN,tr|A0A6Q8PHA3|A0A6Q8PHA3_HUMAN,tr|A0A3B3ITL7|A0A3B3ITL7_HUMAN,tr|F8VZY7|F8VZY7_HUMAN,tr|B0QYY4|B0QYY4_HUMAN,tr|J3KNW3|J3KNW3_HUMAN,tr|F8VZG9|F8VZG9_HUMAN,tr|J3QRF4|J3QRF4_HUMAN,tr|F8VRS4|F8VRS4_HUMAN,tr|A0A6Q8PFM4|A0A6Q8PFM4_HUMAN,tr|S4R469|S4R469_HUMAN,tr|A0A804HKG7|A0A804HKG7_HUMAN,tr|A0A0G2JRA5|A0A0G2JRA5_HUMAN,tr|A0A804HJM2|A0A804HJM2_HUMAN,tr|J3QQZ2|J3QQZ2_HUMAN,tr|I3L1D4|I3L1D4_HUMAN,tr|B0QYY7|B0QYY7_HUMAN,tr|A0A0G2JSB3|A0A0G2JSB3_HUMAN" 28 1257.7209 1.15 82459 13106 2 1257.717551 629.8677 RNA binding protein fox-1 homolog 2 OS=Homo sapiens OX=9606 GN=RBFOX2 PE=1 SV=3 12 2365.1 - 1.10E+06 - - - -2.6739 - 2.303 0.463 - 248.5 1 2 0 -0.0034 10 0 0 0 1.20E+08 1.04E+08 - - - 4.7882 0.9999 221125_WJC_METTL3_EV_vs_WT_F06.13107.13107.4 0.000469 17/72 K.LVEHGLNETIHIR[166.11].G sp|Q7Z3B4|NUP54_HUMAN 1 1539.8397 2.04 82460 13107 4 1539.835468 385.9672 Nucleoporin p54 OS=Homo sapiens OX=9606 GN=NUP54 PE=1 SV=2 6 2365.2 - 642298 - - - -2.7451 - 2.817 0.465 - 239.4 1 2 0 -0.0042 13 0 0 0 1.13E+08 5.53E+07 - - - 3.6562 0.9999 221125_WJC_METTL3_EV_vs_WT_F06.13114.13114.4 1.00E-05 19/72 K.LVEHGLNETIHIR.G sp|Q7Z3B4|NUP54_HUMAN 1 1529.8314 2.04 82465 13114 4 1529.828603 383.4651 Nucleoporin p54 OS=Homo sapiens OX=9606 GN=NUP54 PE=1 SV=2 6 2366 - 2.95E+06 - - - -1.8446 - 3.513 0.419 - 372.3 1 2 0 -0.0028 13 0 0 0 1.13E+08 5.53E+07 - - - 3.3381 0.9999 221125_WJC_METTL3_EV_vs_WT_F06.13116.13116.3 3.00E-05 Sep-48 K.EIYTHFTC[160.03]ATDTK.N "sp|P63096|GNAI1_HUMAN,sp|P04899|GNAI2_HUMAN,sp|P08754|GNAI3_HUMAN" 3 1585.7083 1.06 82467 13116 3 1585.708241 529.5767 Guanine nucleotide-binding protein G(i) subunit alpha-1 OS=Homo sapiens OX=9606 GN=GNAI1 PE=1 SV=2 5.32 2366.1 - 2.80E+06 - - - -0.0114 - 2.141 0.425 - 83 1 2 0 0 13 0 0 0 4.55E+07 4.31E+07 - - - 5.3424 0.9997 221125_WJC_METTL3_EV_vs_WT_F06.13118.13118.3 1.34E-06 15/36 K.R[166.11]LHVSNIPFR.F "sp|O43251|RFOX2_HUMAN,sp|Q9NWB1|RFOX1_HUMAN,sp|A6NFN3|RFOX3_HUMAN,tr|A0A6Q8PGE0|A0A6Q8PGE0_HUMAN,tr|A0A6Q8PH77|A0A6Q8PH77_HUMAN,tr|A0A286YEU2|A0A286YEU2_HUMAN,tr|A0A087X2B1|A0A087X2B1_HUMAN,tr|F8VR27|F8VR27_HUMAN,tr|B7Z1U7|B7Z1U7_HUMAN,tr|B0QYY6|B0QYY6_HUMAN,tr|B0QYV1|B0QYV1_HUMAN,tr|A0A6Q8PHA3|A0A6Q8PHA3_HUMAN,tr|A0A3B3ITL7|A0A3B3ITL7_HUMAN,tr|F8VZY7|F8VZY7_HUMAN,tr|B0QYY4|B0QYY4_HUMAN,tr|J3KNW3|J3KNW3_HUMAN,tr|F8VZG9|F8VZG9_HUMAN,tr|J3QRF4|J3QRF4_HUMAN,tr|F8VRS4|F8VRS4_HUMAN,tr|A0A6Q8PFM4|A0A6Q8PFM4_HUMAN,tr|S4R469|S4R469_HUMAN,tr|A0A804HKG7|A0A804HKG7_HUMAN,tr|A0A0G2JRA5|A0A0G2JRA5_HUMAN,tr|A0A804HJM2|A0A804HJM2_HUMAN,tr|J3QQZ2|J3QQZ2_HUMAN,tr|I3L1D4|I3L1D4_HUMAN,tr|B0QYY7|B0QYY7_HUMAN,tr|A0A0G2JSB3|A0A0G2JSB3_HUMAN" 28 1247.7126 - 82469 13118 3 1247.708993 416.9115 RNA binding protein fox-1 homolog 2 OS=Homo sapiens OX=9606 GN=RBFOX2 PE=1 SV=3 12 2366.3 - 1.55E+06 - - - -2.9262 - 3.023 0.329 - 295.5 1 2 0 -0.0037 10 0 0 0 - - - - - 5.4377 1 221125_WJC_METTL3_EV_vs_WT_F06.13122.13122.3 1.92E-07 16/68 K.IWDPTPSHTPAGAATPGR[166.11].G sp|O75533|SF3B1_HUMAN 1 1840.9096 1.29 82472 13122 3 1840.911091 614.6438 Splicing factor 3B subunit 1 OS=Homo sapiens OX=9606 GN=SF3B1 PE=1 SV=3 6.74 2366.7 - 3.66E+06 - - - 0.8284 - 3.051 0.538 - 227.6 1 2 0 0.0015 18 0 0 0 1.56E+08 1.21E+08 - - - 7.3154 0.9832 221125_WJC_METTL3_EV_vs_WT_F06.13124.13124.3 0.00252 14/56 Q.NAAVQAVNAHSNILK.A "sp|Q16891|MIC60_HUMAN,tr|B9A067|B9A067_HUMAN,tr|C9J406|C9J406_HUMAN,tr|H7C463|H7C463_HUMAN" 4 1548.8372 1.35 82473 13124 3 1548.836339 517.2864 MICOS complex subunit MIC60 OS=Homo sapiens OX=9606 GN=IMMT PE=1 SV=1 8.76 2366.9 - 3.41E+06 - - - -0.5811 - 2.295 0.362 - 262.3 1 1 0 -0.0009 15 0 0 0 4.83E+07 3.57E+07 - - - 4.7434 0.9986 221125_WJC_METTL3_EV_vs_WT_F06.13126.13126.3 0.000159 20/56 Q.NAAVQAVNAHSNILK[136.11].A "sp|Q16891|MIC60_HUMAN,tr|B9A067|B9A067_HUMAN,tr|C9J406|C9J406_HUMAN,tr|H7C463|H7C463_HUMAN" 4 1556.8514 1.35 82475 13126 3 1556.850007 519.9578 MICOS complex subunit MIC60 OS=Homo sapiens OX=9606 GN=IMMT PE=1 SV=1 8.76 2367 - 2.46E+06 - - - -0.9198 - 3.591 0.52 - 589 1 1 0 -0.0014 15 0 0 0 4.83E+07 3.57E+07 - - - 7.673 1 221125_WJC_METTL3_EV_vs_WT_F06.13127.13127.2 6.59E-09 16/28 R.HGGGGGGFGGGGFGS.R sp|P35908|K22E_HUMAN 1 1163.4744 - 82476 13127 2 1163.473582 582.7445 "Keratin, type II cytoskeletal 2 epidermal OS=Homo sapiens OX=9606 GN=KRT2 PE=1 SV=2" 6.74 2367.1 - 1.21E+06 - - - -0.7323 - 2.394 0.693 - 372.4 1 1 0 -0.0009 15 0 0 0 - - - - - 6.3055 0.9999 221125_WJC_METTL3_EV_vs_WT_F06.13130.13130.2 1.00E-08 15/28 R.NLTEDNSQNQDLIAK[136.11].M "sp|Q9UBB4|ATX10_HUMAN,tr|B1AHE3|B1AHE3_HUMAN" 2 1709.8312 0.38 82477 13130 2 1709.830324 855.9229 Ataxin-10 OS=Homo sapiens OX=9606 GN=ATXN10 PE=1 SV=1 4.03 2367.5 - 2.06E+06 - - - -0.4872 - 3.163 0.38 - 536.1 1 2 0 -0.0008 15 0 0 0 2.02E+07 5.34E+07 - - - 4.6785 1 221125_WJC_METTL3_EV_vs_WT_F06.13134.13134.3 1.22E-05 14/44 K.HIGVC[160.03]ISVANNR.L "sp|O60506|HNRPQ_HUMAN,sp|O43390|HNRPR_HUMAN,tr|A0A7I2YQV8|A0A7I2YQV8_HUMAN,tr|B4DT28|B4DT28_HUMAN,tr|A0A7I2YQN2|A0A7I2YQN2_HUMAN,tr|A0A7I2V5Q6|A0A7I2V5Q6_HUMAN,tr|A0A7I2V4Z0|A0A7I2V4Z0_HUMAN,tr|A0A6Q8PHG0|A0A6Q8PHG0_HUMAN,tr|B7Z645|B7Z645_HUMAN,tr|A0A6Q8PH31|A0A6Q8PH31_HUMAN,tr|A0A6Q8PEX7|A0A6Q8PEX7_HUMAN,tr|A0A7I2V2F2|A0A7I2V2F2_HUMAN,tr|A0A7I2V346|A0A7I2V346_HUMAN,tr|A0A7I2V309|A0A7I2V309_HUMAN" 14 1338.6827 2.01 82481 13134 3 1338.681577 447.2348 Heterogeneous nuclear ribonucleoprotein Q OS=Homo sapiens OX=9606 GN=SYNCRIP PE=1 SV=2 8.26 2367.9 - 1.79E+06 - - - -0.8038 - 2.158 0.508 - 229.1 1 2 0 -0.0011 12 0 0 0 2.96E+07 1.48E+07 - - - 6.3355 1 221125_WJC_METTL3_EV_vs_WT_F06.13139.13139.3 0.000326 14/48 K.LVEHGLNETIHIR[166.11].G sp|Q7Z3B4|NUP54_HUMAN 1 1539.8397 1.98 82484 13139 3 1539.838977 514.2872 Nucleoporin p54 OS=Homo sapiens OX=9606 GN=NUP54 PE=1 SV=2 6 2368.5 - 3.32E+06 - - - -0.4663 - 3.283 0.486 - 307.8 1 2 0 -0.0007 13 0 0 0 9.87E+07 4.98E+07 - - - 7.1813 1 221125_WJC_METTL3_EV_vs_WT_F06.13140.13140.3 5.47E-09 23/56 K.C[160.03]VLPEEDSGELAK[136.11]PK[136.11].L sp|Q9Y3F4|STRAP_HUMAN 1 1686.8469 0.72 82485 13140 3 1686.849605 563.2896 Serine-threonine kinase receptor-associated protein OS=Homo sapiens OX=9606 GN=STRAP PE=1 SV=1 4.41 2368.6 - 1.94E+06 - - - 1.5816 - 3.759 0.598 - 586.6 1 2 0 0.0027 15 0 0 0 2.05E+07 2.85E+07 - - - 8.6616 0.9955 221125_WJC_METTL3_EV_vs_WT_F06.13141.13141.3 4.69E-06 17/44 A.IVHINHQPFLER.G "sp|P17844|DDX5_HUMAN,tr|A0A7I2V5F5|A0A7I2V5F5_HUMAN,tr|J3QRN5|J3QRN5_HUMAN,tr|A0A7I2V507|A0A7I2V507_HUMAN,tr|J3KTA4|J3KTA4_HUMAN,tr|A0A0G2JLI4|A0A0G2JLI4_HUMAN,tr|A0A7I2V2S0|A0A7I2V2S0_HUMAN,tr|J3QRQ7|J3QRQ7_HUMAN" 8 1501.8154 2.15 82486 13141 3 1501.815607 501.6124 Probable ATP-dependent RNA helicase DDX5 OS=Homo sapiens OX=9606 GN=DDX5 PE=1 SV=1 6.92 2368.7 - 1.41E+06 - - - 0.1505 - 2.562 0.442 - 327.7 1 1 0 0.0002 12 0 0 0 3.95E+07 1.83E+07 - - - 6.0755 1 221125_WJC_METTL3_EV_vs_WT_F06.13143.13143.3 5.39E-07 16/56 R.VLQVQAQVQSQTQPR[166.11].L "sp|Q9ULV3|CIZ1_HUMAN,tr|Q5SYW2|Q5SYW2_HUMAN,tr|F5H2X7|F5H2X7_HUMAN,tr|H0Y5D5|H0Y5D5_HUMAN,tr|A0A494C0L7|A0A494C0L7_HUMAN,tr|Q9BTG3|Q9BTG3_HUMAN" 6 1718.9303 2.95 82488 13143 3 1718.931309 573.984 Cip1-interacting zinc finger protein OS=Homo sapiens OX=9606 GN=CIZ1 PE=1 SV=2 9.72 2369 - 807924 - - - 0.5864 - 3.034 0.513 - 388.1 1 2 0 0.001 15 0 0 0 3.42E+08 1.16E+08 - - - 7.1553 1 221125_WJC_METTL3_EV_vs_WT_F06.13146.13146.3 0.00273 15/48 K.LVEHGLNETIHIR.G sp|Q7Z3B4|NUP54_HUMAN 1 1529.8314 1.98 82489 13146 3 1529.830468 510.9511 Nucleoporin p54 OS=Homo sapiens OX=9606 GN=NUP54 PE=1 SV=2 6 2369.4 - 6.28E+06 - - - -0.6256 - 3.07 0.514 - 387.8 1 2 0 -0.001 13 0 0 0 9.87E+07 4.98E+07 - - - 7.3115 1 221125_WJC_METTL3_EV_vs_WT_F06.13147.13147.3 5.84E-05 15/40 R.SLGTADVHFER.K "sp|Q86V81|THOC4_HUMAN,tr|E9PB61|E9PB61_HUMAN" 2 1230.5993 0.66 82490 13147 3 1230.599385 411.207 THO complex subunit 4 OS=Homo sapiens OX=9606 GN=ALYREF PE=1 SV=3 5.3 2369.4 - 4.19E+06 - - - 0.0691 - 2.52 0.453 - 304 1 2 0 0.0001 11 0 0 0 1.46E+08 2.22E+08 - - - 6.2161 0.9999 221125_WJC_METTL3_EV_vs_WT_F06.13148.13148.3 0.00144 17/40 K.LK[136.11]VSELK[136.11]EELK[136.11].K "sp|Q00839|HNRPU_HUMAN,tr|A0A1W2PPS1|A0A1W2PPS1_HUMAN,tr|A0A1X7SBS1|A0A1X7SBS1_HUMAN" 3 1338.8185 0.95 82491 13148 3 1338.816629 447.2801 Heterogeneous nuclear ribonucleoprotein U OS=Homo sapiens OX=9606 GN=HNRNPU PE=1 SV=6 6.23 2369.5 - 3.35E+06 - - - -1.3736 - 2.6 0.521 - 265.5 1 2 2 -0.0018 11 0 0 0 1.14E+08 1.20E+08 - - - 7.0626 1 221125_WJC_METTL3_EV_vs_WT_F06.13149.13149.3 2.76E-07 15/44 R.TNSTFNQVVLK[136.11]R[166.11].L "sp|Q07020|RL18_HUMAN,tr|J3QQ67|J3QQ67_HUMAN,tr|G3V203|G3V203_HUMAN,tr|F8VYV2|F8VYV2_HUMAN,tr|H0YHA7|H0YHA7_HUMAN,tr|A0A075B7A0|A0A075B7A0_HUMAN" 6 1423.7902 0.65 82492 13149 3 1423.789421 475.604 60S ribosomal protein L18 OS=Homo sapiens OX=9606 GN=RPL18 PE=1 SV=2 11 2369.5 - 2.45E+06 - - - -0.5703 - 2.798 0.457 - 413.3 1 2 0 -0.0008 12 0 0 0 3.52E+07 5.45E+07 - - - 6.4868 0.9999 221125_WJC_METTL3_EV_vs_WT_F06.13152.13152.2 1.97E-09 28-Nov R.NLTEDNSQNQDLIAK.M "sp|Q9UBB4|ATX10_HUMAN,tr|B1AHE3|B1AHE3_HUMAN" 2 1701.817 0.37 82495 13152 2 1701.816266 851.9158 Ataxin-10 OS=Homo sapiens OX=9606 GN=ATXN10 PE=1 SV=1 4.03 2369.9 - 778373 - - - -0.406 - 2.662 0.459 - 279.9 1 2 0 -0.0007 15 0 0 0 2.02E+07 5.43E+07 - - - 4.8381 0.9993 221125_WJC_METTL3_EV_vs_WT_F06.13155.13155.3 0.00506 15/44 K.ANKLDHVVTIIK.G "sp|Q99873|ANM1_HUMAN,tr|E9PQ98|E9PQ98_HUMAN,tr|E9PKG1|E9PKG1_HUMAN,tr|E9PNR9|E9PNR9_HUMAN,tr|H0YDE4|H0YDE4_HUMAN,tr|E9PIX6|E9PIX6_HUMAN" 6 1349.8031 1.97 82496 13155 3 1349.803084 450.9416 Protein arginine N-methyltransferase 1 OS=Homo sapiens OX=9606 GN=PRMT1 PE=1 SV=3 8.64 2370.3 - 2.38E+06 - - - -0.0007 - 2.531 0.327 - 289 1 2 1 0 12 0 0 0 5.28E+08 2.68E+08 - - - 4.7597 1 221125_WJC_METTL3_EV_vs_WT_F06.13156.13156.2 4.80E-11 18/28 R.VLQVQAQVQSQTQPR.L "sp|Q9ULV3|CIZ1_HUMAN,tr|Q5SYW2|Q5SYW2_HUMAN,tr|F5H2X7|F5H2X7_HUMAN,tr|H0Y5D5|H0Y5D5_HUMAN,tr|A0A494C0L7|A0A494C0L7_HUMAN,tr|Q9BTG3|Q9BTG3_HUMAN" 6 1708.922 2.89 82497 13156 2 1708.920659 855.4683 Cip1-interacting zinc finger protein OS=Homo sapiens OX=9606 GN=CIZ1 PE=1 SV=2 9.72 2370.3 - 1.90E+06 - - - -0.8028 - 3.364 0.647 - 1324.4 1 2 0 -0.0014 15 0 0 0 1.11E+08 3.84E+07 - - - 6.8018 0.9999 221125_WJC_METTL3_EV_vs_WT_F06.13157.13157.3 3.00E-05 14/44 R.TNSTFNQVVLKR.L "sp|Q07020|RL18_HUMAN,tr|J3QQ67|J3QQ67_HUMAN,tr|G3V203|G3V203_HUMAN,tr|F8VYV2|F8VYV2_HUMAN,tr|H0YHA7|H0YHA7_HUMAN,tr|A0A075B7A0|A0A075B7A0_HUMAN" 6 1405.7678 0.7 82498 13157 3 1405.765675 469.5965 60S ribosomal protein L18 OS=Homo sapiens OX=9606 GN=RPL18 PE=1 SV=2 11 2370.4 - 2.10E+06 - - - -1.4853 - 2.534 0.432 - 352.1 1 2 0 -0.0021 12 0 0 0 3.45E+07 4.89E+07 - - - 5.9331 0.9977 221125_WJC_METTL3_EV_vs_WT_F06.13158.13158.2 7.12E-06 18-Dec R.DENWDKEIEK.M sp|Q96A49|SYAP1_HUMAN 1 1304.5885 1.3 82499 13158 2 1304.586098 653.3015 Synapse-associated protein 1 OS=Homo sapiens OX=9606 GN=SYAP1 PE=1 SV=1 4.18 2370.5 - 1.46E+06 - - - -1.8113 - 2.521 0.461 - 755.7 1 2 1 -0.0024 10 0 0 0 1.25E+08 9.63E+07 - - - 5.0262 1 221125_WJC_METTL3_EV_vs_WT_F06.13160.13160.2 1.59E-08 16/28 R.VLQVQAQVQSQTQPR[166.11].L "sp|Q9ULV3|CIZ1_HUMAN,tr|Q5SYW2|Q5SYW2_HUMAN,tr|F5H2X7|F5H2X7_HUMAN,tr|H0Y5D5|H0Y5D5_HUMAN,tr|A0A494C0L7|A0A494C0L7_HUMAN,tr|Q9BTG3|Q9BTG3_HUMAN" 6 1718.9303 2.85 82501 13160 2 1718.931723 860.4724 Cip1-interacting zinc finger protein OS=Homo sapiens OX=9606 GN=CIZ1 PE=1 SV=2 9.72 2370.8 - 924550 - - - 0.8273 - 3.205 0.603 - 981.7 1 2 0 0.0014 15 0 0 0 1.09E+08 3.84E+07 - - - 6.3578 1 221125_WJC_METTL3_EV_vs_WT_F06.13162.13162.3 2.49E-07 13/48 K.AQADFDSC[160.03]ISSQR.L sp|Q5JSZ5|PRC2B_HUMAN 1 1483.6362 0.35 82503 13162 3 1483.632884 495.5527 Protein PRRC2B OS=Homo sapiens OX=9606 GN=PRRC2B PE=1 SV=2 4.21 2371 - 403808 - - - -2.2054 - 2.686 0.564 - 263.4 1 2 0 -0.0033 13 0 0 0 1.04E+07 3.02E+07 - - - 7.506 0.9667 221125_WJC_METTL3_EV_vs_WT_F06.13163.13163.2 0.0275 20-Oct K.LKVSELKEELK.K "sp|Q00839|HNRPU_HUMAN,tr|A0A1W2PPS1|A0A1W2PPS1_HUMAN,tr|A0A1X7SBS1|A0A1X7SBS1_HUMAN" 3 1314.7759 0.92 82504 13163 2 1314.779262 658.3952 Heterogeneous nuclear ribonucleoprotein U OS=Homo sapiens OX=9606 GN=HNRNPU PE=1 SV=6 6.23 2371.2 - 308834 - - - 2.5814 - 1.9 0.229 - 198.9 1 2 2 0.0034 11 0 0 0 1.06E+07 1.15E+07 - - - 2.4677 1 221125_WJC_METTL3_EV_vs_WT_F06.13166.13166.3 1.75E-07 15/56 R.VLQVQAQVQSQTQPR.L "sp|Q9ULV3|CIZ1_HUMAN,tr|Q5SYW2|Q5SYW2_HUMAN,tr|F5H2X7|F5H2X7_HUMAN,tr|H0Y5D5|H0Y5D5_HUMAN,tr|A0A494C0L7|A0A494C0L7_HUMAN,tr|Q9BTG3|Q9BTG3_HUMAN" 6 1708.922 2.76 82505 13166 3 1708.920539 570.648 Cip1-interacting zinc finger protein OS=Homo sapiens OX=9606 GN=CIZ1 PE=1 SV=2 9.72 2371.6 - 1.16E+07 - - - -0.8731 - 2.679 0.525 - 274 1 2 0 -0.0015 15 0 0 0 3.20E+08 1.16E+08 - - - 6.9642 1 221125_WJC_METTL3_EV_vs_WT_F06.13167.13167.3 6.93E-10 17/52 K.YNEQHVPGSPFTAR.V "sp|P21333|FLNA_HUMAN,tr|Q60FE5|Q60FE5_HUMAN" 2 1601.7587 1.04 82506 13167 3 1601.758051 534.9268 Filamin-A OS=Homo sapiens OX=9606 GN=FLNA PE=1 SV=4 6.75 2371.6 - 6.40E+06 - - - -0.3765 - 3.242 0.7 - 337.9 1 2 0 -0.0006 14 0 0 0 1.20E+08 1.16E+08 - - - 9.4699 0.9999 221125_WJC_METTL3_EV_vs_WT_F06.13170.13170.3 0.415 18/56 R.R[166.11]PGSLPAPPPSQLPR[166.11].N "sp|P39880|CUX1_HUMAN,tr|A0A2R8Y852|A0A2R8Y852_HUMAN" 2 1588.8953 1.49 82509 13170 3 1588.896312 530.639 Homeobox protein cut-like 1 OS=Homo sapiens OX=9606 GN=CUX1 PE=1 SV=3 12 2371.8 - 2.16E+06 - - - 0.6684 - 2.994 0.377 - 468.1 1 2 0 0.0011 15 0 0 0 3.19E+08 2.14E+08 - - - 5.6043 0.9999 221125_WJC_METTL3_EV_vs_WT_F06.13171.13171.3 6.48E-05 Dec-36 K.K[136.11]LEIGFNGNR[166.11].L "sp|Q9HD45|TM9S3_HUMAN,tr|Q5TB53|Q5TB53_HUMAN" 2 1164.637 1.66 82510 13171 3 1164.635892 389.2196 Transmembrane 9 superfamily member 3 OS=Homo sapiens OX=9606 GN=TM9SF3 PE=1 SV=2 8.75 2371.9 - 1.47E+06 - - - -0.9737 - 2.033 0.442 - 156.3 1 2 0 -0.0011 10 0 0 0 4.96E+07 2.99E+07 - - - 5.5396 0.9999 221125_WJC_METTL3_EV_vs_WT_F06.13172.13172.3 0.0643 15/44 R.RLEESDVLQEAR.R "sp|O43615|TIM44_HUMAN,tr|M0R301|M0R301_HUMAN,tr|M0R124|M0R124_HUMAN,tr|M0QXU7|M0QXU7_HUMAN" 4 1443.7318 1.08 82511 13172 3 1443.733401 482.2512 Mitochondrial import inner membrane translocase subunit TIM44 OS=Homo sapiens OX=9606 GN=TIMM44 PE=1 SV=2 4.41 2372 - 1.38E+06 - - - 1.129 - 2.681 0.395 - 384.2 1 2 0 0.0016 12 0 0 0 2.29E+08 2.11E+08 - - - 5.677 1 221125_WJC_METTL3_EV_vs_WT_F06.13175.13175.2 2.46E-10 14/24 H.SC[160.03]NWVAASGPC[160.03]DK.R sp|Q9H7S9|ZN703_HUMAN 1 1450.5969 2.11 82514 13175 2 1450.595685 726.3057 Zinc finger protein 703 OS=Homo sapiens OX=9606 GN=ZNF703 PE=1 SV=1 5.55 2372.4 - 624384 - - - -0.861 - 2.759 0.71 - 584.8 1 1 0 -0.0013 13 0 0 0 2.41E+07 1.14E+07 - - - 6.8894 0.9995 221125_WJC_METTL3_EV_vs_WT_F06.13176.13176.3 0.000755 14/76 R.EGTGALEKPDPVAAGSPGLK.S "sp|Q96H86|ZN764_HUMAN,tr|B7Z5R0|B7Z5R0_HUMAN" 2 1892.9844 0.92 82515 13176 3 1892.985593 632.0021 Zinc finger protein 764 OS=Homo sapiens OX=9606 GN=ZNF764 PE=1 SV=2 4.68 2372.5 - 616051 - - - 0.6529 - 2.249 0.298 - 144.8 1 2 0 0.0012 20 0 0 0 1.52E+07 1.64E+07 - - - 3.8283 0.9996 221125_WJC_METTL3_EV_vs_WT_F06.13181.13181.3 0.146 16/56 R.RPGSLPAPPPSQLPR.N "sp|P39880|CUX1_HUMAN,tr|A0A2R8Y852|A0A2R8Y852_HUMAN" 2 1568.8787 1.48 82518 13181 3 1568.878367 523.9668 Homeobox protein cut-like 1 OS=Homo sapiens OX=9606 GN=CUX1 PE=1 SV=3 12 2373 - 3.85E+06 - - - -0.2186 - 2.667 0.263 - 366.4 1 2 0 -0.0003 15 0 0 0 3.45E+08 2.32E+08 - - - 4.0318 1 221125_WJC_METTL3_EV_vs_WT_F06.13182.13182.2 0.000105 17/22 K.ANKLDHVVTIIK.G "sp|Q99873|ANM1_HUMAN,tr|E9PQ98|E9PQ98_HUMAN,tr|E9PKG1|E9PKG1_HUMAN,tr|E9PNR9|E9PNR9_HUMAN,tr|H0YDE4|H0YDE4_HUMAN,tr|E9PIX6|E9PIX6_HUMAN" 6 1349.8031 2.19 82519 13182 2 1349.803497 675.9088 Protein arginine N-methyltransferase 1 OS=Homo sapiens OX=9606 GN=PRMT1 PE=1 SV=3 8.64 2373.1 - 1.75E+06 - - - 0.3052 - 3.3 0.497 - 883.5 1 2 1 0.0004 12 0 0 0 6.29E+07 2.87E+07 - - - 5.8531 0.9993 221125_WJC_METTL3_EV_vs_WT_F06.13184.13184.2 6.16E-05 17/22 R.RLEESDVLQEAR.R "sp|O43615|TIM44_HUMAN,tr|M0R301|M0R301_HUMAN,tr|M0R124|M0R124_HUMAN,tr|M0QXU7|M0QXU7_HUMAN" 4 1443.7318 1.14 82521 13184 2 1443.726242 722.8732 Mitochondrial import inner membrane translocase subunit TIM44 OS=Homo sapiens OX=9606 GN=TIMM44 PE=1 SV=2 4.41 2373.4 - 829928 - - - -3.8297 - 3.1 0.471 - 382.6 1 2 0 -0.0055 12 0 0 0 4.77E+07 4.19E+07 - - - 5.495 0.9999 221125_WJC_METTL3_EV_vs_WT_F06.13190.13190.3 7.13E-07 14/44 K.ANK[136.11]LDHVVTIIK[136.11].G "sp|Q99873|ANM1_HUMAN,tr|E9PQ98|E9PQ98_HUMAN,tr|E9PKG1|E9PKG1_HUMAN,tr|E9PNR9|E9PNR9_HUMAN,tr|H0YDE4|H0YDE4_HUMAN,tr|E9PIX6|E9PIX6_HUMAN" 6 1365.8315 1.97 82525 13190 3 1365.83076 456.2844 Protein arginine N-methyltransferase 1 OS=Homo sapiens OX=9606 GN=PRMT1 PE=1 SV=3 8.64 2374.1 - 1.73E+07 - - - -0.5308 - 2.661 0.468 - 310.9 1 2 1 -0.0007 12 0 0 0 5.28E+08 2.68E+08 - - - 6.4704 1 221125_WJC_METTL3_EV_vs_WT_F06.13191.13191.2 5.74E-11 13/24 K.AQADFDSC[160.03]ISSQR.L sp|Q5JSZ5|PRC2B_HUMAN 1 1483.6362 1.47 82526 13191 2 1483.636005 742.8254 Protein PRRC2B OS=Homo sapiens OX=9606 GN=PRRC2B PE=1 SV=2 4.21 2374.2 - 3.80E+06 - - - -0.1018 - 2.72 0.677 - 615.5 1 2 0 -0.0002 13 0 0 0 8.44E+07 5.76E+07 - - - 6.6094 0.9999 221125_WJC_METTL3_EV_vs_WT_F06.13194.13194.2 3.75E-06 18/22 R.R[166.11]LEESDVLQEAR[166.11].R "sp|O43615|TIM44_HUMAN,tr|M0R301|M0R301_HUMAN,tr|M0R124|M0R124_HUMAN,tr|M0QXU7|M0QXU7_HUMAN" 4 1463.7483 1.14 82529 13194 2 1463.748134 732.8814 Mitochondrial import inner membrane translocase subunit TIM44 OS=Homo sapiens OX=9606 GN=TIMM44 PE=1 SV=2 4.41 2374.4 - 1.41E+06 - - - -0.1209 - 2.699 0.502 - 451.2 1 2 0 -0.0002 12 0 0 0 4.77E+07 4.19E+07 - - - 5.3612 0.989 221125_WJC_METTL3_EV_vs_WT_F06.13195.13195.3 0.000317 Aug-32 V.KQYFEQFGK.V "sp|O43347|MSI1H_HUMAN,sp|Q96DH6|MSI2H_HUMAN,tr|B4DHE8|B4DHE8_HUMAN,tr|H0YHB7|H0YHB7_HUMAN,tr|A0A6Q8PF05|A0A6Q8PF05_HUMAN,tr|B4DM51|B4DM51_HUMAN,tr|J3KTC1|J3KTC1_HUMAN" 7 1173.5819 1.23 82530 13195 3 1173.583509 392.2012 RNA-binding protein Musashi homolog 1 OS=Homo sapiens OX=9606 GN=MSI1 PE=1 SV=1 8.5 2374.5 - 686470 - - - 1.406 - 1.846 0.453 - 84 1 1 0 0.0016 9 0 0 0 8.54E+06 6.94E+06 - - - 5.4376 1 221125_WJC_METTL3_EV_vs_WT_F06.13198.13198.2 1.33E-09 13/24 K.AQADFDSC[160.03]ISSQR[166.11].L sp|Q5JSZ5|PRC2B_HUMAN 1 1493.6444 1.49 82532 13198 2 1493.643032 747.8295 Protein PRRC2B OS=Homo sapiens OX=9606 GN=PRRC2B PE=1 SV=2 4.21 2374.9 - 2.03E+06 - - - -0.9333 - 2.82 0.742 - 608.3 1 2 0 -0.0014 13 0 0 0 8.66E+07 5.82E+07 - - - 7.1818 0.9998 221125_WJC_METTL3_EV_vs_WT_F06.13200.13200.3 0.000196 15/44 R.R[166.11]LEESDVLQEAR[166.11].R "sp|O43615|TIM44_HUMAN,tr|M0R301|M0R301_HUMAN,tr|M0R124|M0R124_HUMAN,tr|M0QXU7|M0QXU7_HUMAN" 4 1463.7483 1.08 82533 13200 3 1463.748517 488.9234 Mitochondrial import inner membrane translocase subunit TIM44 OS=Homo sapiens OX=9606 GN=TIMM44 PE=1 SV=2 4.41 2375.1 - 1.34E+07 - - - 0.1407 - 2.834 0.285 - 355.3 1 2 0 0.0002 12 0 0 0 2.29E+08 2.12E+08 - - - 4.6048 1 221125_WJC_METTL3_EV_vs_WT_F06.13201.13201.3 5.27E-08 18/52 K.ETTESLHGDISSLK.T "sp|P35658|NU214_HUMAN,tr|A0A0A0MSW3|A0A0A0MSW3_HUMAN,tr|A0A494BZU9|A0A494BZU9_HUMAN,tr|A0A494C1F2|A0A494C1F2_HUMAN" 4 1515.7417 1.89 82534 13201 3 1515.73969 506.2545 Nuclear pore complex protein Nup214 OS=Homo sapiens OX=9606 GN=NUP214 PE=1 SV=2 4.65 2375.1 - 1.19E+07 - - - -1.3043 - 2.968 0.442 - 579.4 1 2 0 -0.002 14 0 0 0 3.35E+08 1.77E+08 - - - 6.3584 1 221125_WJC_METTL3_EV_vs_WT_F06.13203.13203.3 1.23E-06 13/52 K.ETTESLHGDISSLK[136.11].T "sp|P35658|NU214_HUMAN,tr|A0A0A0MSW3|A0A0A0MSW3_HUMAN,tr|A0A494BZU9|A0A494BZU9_HUMAN,tr|A0A494C1F2|A0A494C1F2_HUMAN" 4 1523.7559 1.89 82536 13203 3 1523.755623 508.9259 Nuclear pore complex protein Nup214 OS=Homo sapiens OX=9606 GN=NUP214 PE=1 SV=2 4.65 2375.2 - 7.77E+06 - - - -0.1601 - 2.559 0.451 - 283.6 1 2 0 -0.0002 14 0 0 0 3.35E+08 1.77E+08 - - - 6.0652 1 221125_WJC_METTL3_EV_vs_WT_F06.13204.13204.2 4.17E-09 17/20 K.HPENYDLATLK.W "sp|P78347|GTF2I_HUMAN,sp|Q86UP8|GTD2A_HUMAN,sp|Q6EKJ0|GTD2B_HUMAN,tr|A0A494C1N8|A0A494C1N8_HUMAN,tr|A0A087WW90|A0A087WW90_HUMAN,tr|A0A0D9SF80|A0A0D9SF80_HUMAN,tr|A0A494C0I1|A0A494C0I1_HUMAN,tr|A0A494C1K3|A0A494C1K3_HUMAN" 8 1299.6459 1.45 82537 13204 2 1299.646846 650.8302 General transcription factor II-I OS=Homo sapiens OX=9606 GN=GTF2I PE=1 SV=2 5.32 2375.4 - 1.93E+06 - - - 0.7156 - 3.065 0.633 - 869.2 1 2 0 0.0009 11 0 0 0 4.73E+07 3.26E+07 - - - 6.746 1 221125_WJC_METTL3_EV_vs_WT_F06.13206.13206.2 3.23E-10 22/26 K.ETTESLHGDISSLK.T "sp|P35658|NU214_HUMAN,tr|A0A0A0MSW3|A0A0A0MSW3_HUMAN,tr|A0A494BZU9|A0A494BZU9_HUMAN,tr|A0A494C1F2|A0A494C1F2_HUMAN" 4 1515.7417 2.16 82539 13206 2 1515.739371 758.8781 Nuclear pore complex protein Nup214 OS=Homo sapiens OX=9606 GN=NUP214 PE=1 SV=2 4.65 2375.6 - 1.72E+06 - - - -1.5148 - 3.948 0.646 - 2158.5 1 2 0 -0.0023 14 0 0 0 4.76E+07 2.21E+07 - - - 7.2576 0.999 221125_WJC_METTL3_EV_vs_WT_F06.13209.13209.3 2.38E-07 17/76 R.EGTGALEK[136.11]PDPVAAGSPGLK[136.11].S "sp|Q96H86|ZN764_HUMAN,tr|B7Z5R0|B7Z5R0_HUMAN" 2 1909.0128 0.88 82542 13209 3 1910.014935 637.3449 Zinc finger protein 764 OS=Homo sapiens OX=9606 GN=ZNF764 PE=1 SV=2 4.68 2376 - 1.11E+06 - - - 524.9719 - 2.557 0.506 - 258.4 1 2 0 1.0022 20 0 0 0 1.52E+07 1.71E+07 - - - 6.1814 1 221125_WJC_METTL3_EV_vs_WT_F06.13210.13210.2 5.05E-11 18/26 K.ETTESLHGDISSLK[136.11].T "sp|P35658|NU214_HUMAN,tr|A0A0A0MSW3|A0A0A0MSW3_HUMAN,tr|A0A494BZU9|A0A494BZU9_HUMAN,tr|A0A494C1F2|A0A494C1F2_HUMAN" 4 1523.7559 2.16 82543 13210 2 1523.755647 762.8852 Nuclear pore complex protein Nup214 OS=Homo sapiens OX=9606 GN=NUP214 PE=1 SV=2 4.65 2376.1 - 878903 - - - -0.1444 - 3.485 0.566 - 1295.4 1 2 0 -0.0002 14 0 0 0 4.76E+07 2.21E+07 - - - 6.3544 1 221125_WJC_METTL3_EV_vs_WT_F06.13213.13213.2 4.98E-06 14/28 R.ELEIESQTEEQPTTK.Q sp|Q9NYH9|UTP6_HUMAN 1 1760.8316 2.15 82546 13213 2 1760.833163 881.4231 U3 small nucleolar RNA-associated protein 6 homolog OS=Homo sapiens OX=9606 GN=UTP6 PE=1 SV=2 3.98 2376.5 - 619840 - - - 0.8854 - 3.049 0.587 - 481.8 1 2 0 0.0016 15 0 0 0 1.71E+07 7.98E+06 - - - 6.1169 0.9999 221125_WJC_METTL3_EV_vs_WT_F06.13216.13216.3 0.00519 13/36 K.KLEIGFNGNR.L "sp|Q9HD45|TM9S3_HUMAN,tr|Q5TB53|Q5TB53_HUMAN" 2 1146.6146 1.6 82547 13216 3 1146.613584 383.2121 Transmembrane 9 superfamily member 3 OS=Homo sapiens OX=9606 GN=TM9SF3 PE=1 SV=2 8.75 2376.9 - 2.59E+06 - - - -0.8477 - 2.266 0.409 - 190.5 1 2 0 -0.001 10 0 0 0 5.02E+07 3.13E+07 - - - 5.4886 0.9999 221125_WJC_METTL3_EV_vs_WT_F06.13217.13217.3 0.00429 14/48 K.SFIQSSELTQHQR.T sp|Q9UEG4|ZN629_HUMAN 1 1559.7692 0.59 82548 13217 3 1559.770214 520.9303 Zinc finger protein 629 OS=Homo sapiens OX=9606 GN=ZNF629 PE=1 SV=2 6.47 2376.9 - 2.29E+06 - - - 0.6379 - 2.506 0.351 - 244.5 1 2 0 0.001 13 0 0 0 2.96E+07 5.03E+07 - - - 4.9439 1 221125_WJC_METTL3_EV_vs_WT_F06.13218.13218.2 2.94E-05 19/22 K.ANK[136.11]LDHVVTIIK[136.11].G "sp|Q99873|ANM1_HUMAN,tr|E9PQ98|E9PQ98_HUMAN,tr|E9PKG1|E9PKG1_HUMAN,tr|E9PNR9|E9PNR9_HUMAN,tr|H0YDE4|H0YDE4_HUMAN,tr|E9PIX6|E9PIX6_HUMAN" 6 1365.8315 2.19 82549 13218 2 1365.831941 683.923 Protein arginine N-methyltransferase 1 OS=Homo sapiens OX=9606 GN=PRMT1 PE=1 SV=3 8.64 2377 - 2.53E+06 - - - 0.3339 - 3.347 0.542 - 1226.4 1 2 1 0.0005 12 0 0 0 6.29E+07 2.87E+07 - - - 6.2227 0.9973 221125_WJC_METTL3_EV_vs_WT_F06.13221.13221.2 0.0794 18-Aug K.K[136.11]LEIGFNGNR[166.11].L "sp|Q9HD45|TM9S3_HUMAN,tr|Q5TB53|Q5TB53_HUMAN" 2 1164.637 8.6 82552 13221 2 1164.639921 583.3258 Transmembrane 9 superfamily member 3 OS=Homo sapiens OX=9606 GN=TM9SF3 PE=1 SV=2 8.75 2377.3 - 840142 - - - 2.4858 - 1.665 0.28 - 190.7 1 2 0 0.0029 10 0 0 0 1.10E+08 1.28E+07 - - - 2.5312 1 221125_WJC_METTL3_EV_vs_WT_F06.13222.13222.2 3.51E-14 21/36 R.SAAPSTLDSSSTAPAQLGK.K "sp|Q9Y5M8|SRPRB_HUMAN,tr|H7C4H2|H7C4H2_HUMAN" 2 1787.8901 1.38 82553 13222 2 1787.892222 894.9523 Signal recognition particle receptor subunit beta OS=Homo sapiens OX=9606 GN=SRPRB PE=1 SV=3 5.55 2377.4 - 833061 - - - 1.1746 - 3.951 0.726 - 1087.9 1 2 0 0.0021 19 0 0 0 2.08E+07 1.51E+07 - - - 7.7805 1 221125_WJC_METTL3_EV_vs_WT_F06.13223.13223.2 1.93E-11 18/36 R.SAAPSTLDSSSTAPAQLGK[136.11].K "sp|Q9Y5M8|SRPRB_HUMAN,tr|H7C4H2|H7C4H2_HUMAN" 2 1795.9043 1.38 82554 13223 2 1795.902706 898.9594 Signal recognition particle receptor subunit beta OS=Homo sapiens OX=9606 GN=SRPRB PE=1 SV=3 5.55 2377.5 - 647814 - - - -0.8998 - 3.644 0.692 - 736.9 1 2 0 -0.0016 19 0 0 0 2.08E+07 1.51E+07 - - - 7.3307 0.99 221125_WJC_METTL3_EV_vs_WT_F06.13226.13226.3 0.000289 16/60 K.LK[136.11]GEATVSFDDPPSAK[136.11].A "sp|P35637|FUS_HUMAN,tr|H3BPE7|H3BPE7_HUMAN" 2 1676.8592 1.17 82556 13226 3 1676.860095 559.9603 RNA-binding protein FUS OS=Homo sapiens OX=9606 GN=FUS PE=1 SV=1 4.56 2377.9 - 1.22E+06 - - - 0.5242 - 2.585 0.161 - 266.4 1 2 1 0.0009 16 0 0 0 3.33E+07 2.84E+07 - - - 2.7716 0.9997 221125_WJC_METTL3_EV_vs_WT_F06.13228.13228.3 2.29E-05 13/56 R.LPEYTLSQEGGPAHK.R "sp|O75569|PRKRA_HUMAN,tr|B4DJC7|B4DJC7_HUMAN,tr|A0A7I2V3J2|A0A7I2V3J2_HUMAN,tr|A0A7I2V2I8|A0A7I2V2I8_HUMAN,tr|A0A7I2V5H3|A0A7I2V5H3_HUMAN,tr|A0A7I2YQ87|A0A7I2YQ87_HUMAN" 6 1625.8049 1.22 82558 13228 3 1625.810236 542.9423 Interferon-inducible double-stranded RNA-dependent protein kinase activator A OS=Homo sapiens OX=9606 GN=PRKRA PE=1 SV=1 5.4 2378.1 - 1.64E+06 - - - 3.2599 - 2.471 0.435 - 217.4 1 2 0 0.0053 15 0 0 0 2.18E+07 1.78E+07 - - - 5.7488 0.9995 221125_WJC_METTL3_EV_vs_WT_F06.13229.13229.3 0.000815 Oct-36 K.EMEQLVLDK[136.11]K[136.11].Q sp|Q96A49|SYAP1_HUMAN 1 1247.6766 4.03 82559 13229 3 1247.675052 416.8995 Synapse-associated protein 1 OS=Homo sapiens OX=9606 GN=SYAP1 PE=1 SV=1 4.68 2378.1 - 1.46E+06 - - - -1.2599 - 1.692 0.341 - 154.6 1 2 0 -0.0016 10 0 0 0 5.57E+07 1.38E+07 - - - 3.8773 0.9998 221125_WJC_METTL3_EV_vs_WT_F06.13231.13231.2 0.00149 18-Oct K.YEELQVTAGR.H "sp|P48668|K2C6C_HUMAN,sp|O95678|K2C75_HUMAN,sp|P02538|K2C6A_HUMAN" 3 1164.5775 999 82561 13231 2 1164.5788 583.296 "Keratin, type II cytoskeletal 6C OS=Homo sapiens OX=9606 GN=KRT6C PE=1 SV=3" 4.53 2378.3 - 803189 - - - 1.1146 - 2.109 0.431 - 412.2 1 2 0 0.0013 10 0 0 0 1.96E+07 0.00E+00 - - - 4.3069 0.8905 221125_WJC_METTL3_EV_vs_WT_F06.13241.13241.2 8.16E-06 13/24 H.SC[160.03]NWVAASGPC[160.03]DK[136.11].R sp|Q9H7S9|ZN703_HUMAN 1 1458.6111 2.11 82569 13241 2 1458.603387 730.3128 Zinc finger protein 703 OS=Homo sapiens OX=9606 GN=ZNF703 PE=1 SV=1 5.55 2379.5 - 603757 - - - -5.3112 - 2.446 0.578 - 248.5 1 1 0 -0.0077 13 0 0 0 2.41E+07 1.14E+07 - - - 5.6033 0.9697 221125_WJC_METTL3_EV_vs_WT_F06.13242.13242.2 5.59E-06 30-Sep R.GGVSC[160.03]GGLSYSTTPGR.Q "sp|P78386|KRT85_HUMAN,tr|F5GYI5|F5GYI5_HUMAN" 2 1554.7097 25.29 82570 13242 2 1555.707245 778.3621 "Keratin, type II cuticular Hb5 OS=Homo sapiens OX=9606 GN=KRT85 PE=1 SV=1" 8.22 2379.6 - 477453 - - - 641.6561 - 2.182 0.617 - 144.1 1 2 0 0.9976 16 0 0 0 4.57E+06 1.81E+05 - - - 5.2032 0.9656 221125_WJC_METTL3_EV_vs_WT_F06.13243.13243.4 0.0383 Dec-78 R.AIQEHPVVLLPSHR[166.11].S "sp|O15228|GNPAT_HUMAN,tr|Q5TBH8|Q5TBH8_HUMAN,tr|Q5TBH6|Q5TBH6_HUMAN" 3 1604.9026 0.64 82571 13243 4 1604.903265 402.2329 Dihydroxyacetone phosphate acyltransferase OS=Homo sapiens OX=9606 GN=GNPAT PE=1 SV=1 6.96 2379.8 - 407197 - - - 0.3957 - 1.796 0.15 - 98.6 1 2 0 0.0006 14 0 0 0 3.87E+06 6.06E+06 - - - 0.7445 1 221125_WJC_METTL3_EV_vs_WT_F06.13253.13253.3 3.72E-07 13/60 R.EALLSSAVDHGSDEVK[136.11].F "sp|P78371|TCPB_HUMAN,tr|F8VQ14|F8VQ14_HUMAN,tr|F5GWF6|F5GWF6_HUMAN" 3 1663.8144 0.1 82579 13253 3 1663.814795 555.6121 T-complex protein 1 subunit beta OS=Homo sapiens OX=9606 GN=CCT2 PE=1 SV=4 4.31 2380.8 - 1.33E+06 - - - 0.2104 - 2.744 0.475 - 219.6 1 2 0 0.0003 16 0 0 0 1.51E+06 1.47E+07 - - - 6.4257 1 221125_WJC_METTL3_EV_vs_WT_F06.13255.13255.2 1.72E-08 14/20 K.HPENYDLATLK[136.11].W "sp|P78347|GTF2I_HUMAN,sp|Q86UP8|GTD2A_HUMAN,sp|Q6EKJ0|GTD2B_HUMAN,tr|A0A494C1N8|A0A494C1N8_HUMAN,tr|A0A087WW90|A0A087WW90_HUMAN,tr|A0A0D9SF80|A0A0D9SF80_HUMAN,tr|A0A494C0I1|A0A494C0I1_HUMAN,tr|A0A494C1K3|A0A494C1K3_HUMAN" 8 1307.6601 1.45 82581 13255 2 1307.661566 654.8373 General transcription factor II-I OS=Homo sapiens OX=9606 GN=GTF2I PE=1 SV=2 5.32 2381 - 1.06E+06 - - - 1.1089 - 3.057 0.618 - 585 1 2 0 0.0014 11 0 0 0 4.73E+07 3.26E+07 - - - 6.628 1 221125_WJC_METTL3_EV_vs_WT_F06.13256.13256.3 1.04E-07 15/64 K.RPPAAPENTPLVPSGVK.S sp|P48634|PRC2A_HUMAN 1 1728.9523 1.34 82582 13256 3 1728.951369 577.3247 Protein PRRC2A OS=Homo sapiens OX=9606 GN=PRRC2A PE=1 SV=3 8.75 2381.1 - 934680 - - - -0.5205 - 2.939 0.531 - 249.1 1 2 0 -0.0009 17 0 0 0 2.73E+08 2.05E+08 - - - 7.1834 0.9986 221125_WJC_METTL3_EV_vs_WT_F06.13257.13257.3 0.000231 13/72 R.SAAPSTLDSSSTAPAQLGK.K "sp|Q9Y5M8|SRPRB_HUMAN,tr|H7C4H2|H7C4H2_HUMAN" 2 1787.8901 0.9 82583 13257 3 1787.89617 596.9707 Signal recognition particle receptor subunit beta OS=Homo sapiens OX=9606 GN=SRPRB PE=1 SV=3 5.55 2381.2 - 730351 - - - 3.3828 - 2.247 0.338 - 184.1 1 2 0 0.006 19 0 0 0 7.53E+06 8.37E+06 - - - 4.2957 0.9942 221125_WJC_METTL3_EV_vs_WT_F06.13258.13258.2 3.42E-08 13/22 T.TESLHGDISSLK.T "sp|P35658|NU214_HUMAN,tr|A0A0A0MSW3|A0A0A0MSW3_HUMAN,tr|A0A494BZU9|A0A494BZU9_HUMAN,tr|A0A494C1F2|A0A494C1F2_HUMAN" 4 1285.6514 15.31 82584 13258 2 1285.650253 643.833 Nuclear pore complex protein Nup214 OS=Homo sapiens OX=9606 GN=NUP214 PE=1 SV=2 5.29 2381.3 - 303197 - - - -0.8883 - 2.505 0.563 - 545.2 1 1 0 -0.0011 12 0 0 0 2.95E+06 1.93E+05 - - - 5.6151 0.9999 221125_WJC_METTL3_EV_vs_WT_F06.13261.13261.3 7.24E-07 Nov-52 K.TNETYGKLEAVQYK.T "sp|P01040|CYTA_HUMAN,tr|C9J0E4|C9J0E4_HUMAN" 2 1642.8203 102.18 82585 13261 3 1642.821232 548.614 Cystatin-A OS=Homo sapiens OX=9606 GN=CSTA PE=1 SV=1 5.81 2381.7 - 8.21E+06 - - - 0.5965 - 2.518 0.517 - 163.1 1 2 1 0.001 14 0 0 0 9.75E+07 9.54E+05 - - - 6.7579 1 221125_WJC_METTL3_EV_vs_WT_F06.13262.13262.3 2.32E-07 16/56 K.LHAVNAEEC[160.03]NVLQGR[166.11].W "sp|O75521|ECI2_HUMAN,tr|A0A0C4DGA2|A0A0C4DGA2_HUMAN" 2 1718.8398 8.41 82586 13262 3 1718.840711 573.9539 Enoyl-CoA delta isomerase 2 OS=Homo sapiens OX=9606 GN=ECI2 PE=1 SV=4 5.4 2381.8 - 2.22E+06 - - - 0.5463 - 3.477 0.529 - 395.6 1 2 0 0.0009 15 0 0 0 2.41E+08 2.87E+07 - - - 7.6893 0.9997 221125_WJC_METTL3_EV_vs_WT_F06.13263.13263.3 6.00E-05 13/40 R.NSYEPIKEFQK.E sp|Q5VT06|CE350_HUMAN 1 1381.6878 1.5 82587 13263 3 1381.687571 461.5699 Centrosome-associated protein 350 OS=Homo sapiens OX=9606 GN=CEP350 PE=1 SV=1 6.14 2381.9 - 1.11E+06 - - - -0.152 - 2.251 0.422 - 272.3 1 2 1 -0.0002 11 0 0 0 4.39E+07 2.92E+07 - - - 5.5498 0.9996 221125_WJC_METTL3_EV_vs_WT_F06.13265.13265.4 0.00051 18/72 K.LK[136.11]DLYIR[166.11]PNIAQK[136.11].R sp|Q9Y5B9|SP16H_HUMAN 1 1596.9562 0.83 82589 13265 4 1596.955797 400.2463 FACT complex subunit SPT16 OS=Homo sapiens OX=9606 GN=SUPT16H PE=1 SV=1 9.7 2382.1 - 1.04E+06 - - - -0.2411 - 2.499 0.416 - 177.6 1 2 1 -0.0004 13 0 0 0 2.52E+07 3.04E+07 - - - 3.1863 1 221125_WJC_METTL3_EV_vs_WT_F06.13267.13267.2 1.39E-07 16/36 K.LNSVAAAANGLGAEKDPGR.S sp|Q9H7S9|ZN703_HUMAN 1 1809.9333 1.71 82591 13267 2 1809.933575 905.9739 Zinc finger protein 703 OS=Homo sapiens OX=9606 GN=ZNF703 PE=1 SV=1 6.07 2382.3 - 583055 - - - 0.1387 - 3.69 0.576 - 369.3 1 2 1 0.0003 19 0 0 0 3.69E+07 2.16E+07 - - - 6.5052 0.9999 221125_WJC_METTL3_EV_vs_WT_F06.13272.13272.3 8.78E-06 Dec-48 K.DIPVPLSHSTNGK.S "sp|Q14687|GSE1_HUMAN,tr|H7C3B5|H7C3B5_HUMAN,tr|H0Y613|H0Y613_HUMAN" 3 1363.7096 1.38 82594 13272 3 1363.709451 455.5771 Genetic suppressor element 1 OS=Homo sapiens OX=9606 GN=GSE1 PE=1 SV=3 6.74 2382.9 - 1.80E+06 - - - -0.0939 - 2.212 0.451 - 138.8 1 2 0 -0.0001 13 0 0 0 3.93E+07 2.85E+07 - - - 5.7207 0.9273 221125_WJC_METTL3_EV_vs_WT_F06.13277.13277.3 0.00114 Nov-36 Y.SKDNEGSWFR.S "sp|Q9BPW8|NIPS1_HUMAN,tr|H7C2U6|H7C2U6_HUMAN,tr|F8WCR5|F8WCR5_HUMAN" 3 1224.5523 1.2 82599 13277 3 1224.551516 409.1914 Protein NipSnap homolog 1 OS=Homo sapiens OX=9606 GN=NIPSNAP1 PE=1 SV=1 5.79 2383.3 - 1.06E+06 - - - -0.6811 - 1.82 0.4 - 211.6 1 1 1 -0.0008 10 0 0 0 3.55E+07 2.95E+07 - - - 4.7482 0.9731 221125_WJC_METTL3_EV_vs_WT_F06.13278.13278.4 0.0622 13/72 K.LKDLYIRPNIAQK.R sp|Q9Y5B9|SP16H_HUMAN 1 1570.9195 0.83 82600 13278 4 1570.920424 393.7372 FACT complex subunit SPT16 OS=Homo sapiens OX=9606 GN=SUPT16H PE=1 SV=1 9.7 2383.4 - 1.05E+06 - - - 0.5806 - 2.087 0.207 - 102.8 1 2 1 0.0009 13 0 0 0 2.52E+07 3.04E+07 - - - 1.3003 0.9859 221125_WJC_METTL3_EV_vs_WT_F06.13279.13279.2 0.00145 13/22 R.K[136.11]HAASDVDLEIE.S "sp|Q86U44|MTA70_HUMAN,tr|F5H6D8|F5H6D8_HUMAN,tr|H0YFV6|H0YFV6_HUMAN,tr|B4DTN4|B4DTN4_HUMAN" 4 1333.6605 0.001 82601 13279 2 1333.661408 667.8375 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 4.53 2383.6 - 813152 - - - 0.6733 - 2.309 0.379 - 680 1 1 0 0.0009 12 0 0 0 0.00E+00 9.72E+07 - - - 4.0418 0.9999 221125_WJC_METTL3_EV_vs_WT_F06.13280.13280.2 7.56E-05 22-Nov K.KAASITSEVFNK.F sp|Q9Y5B9|SP16H_HUMAN 1 1293.6929 0.73 82602 13280 2 1293.691552 647.8537 FACT complex subunit SPT16 OS=Homo sapiens OX=9606 GN=SUPT16H PE=1 SV=1 8.59 2383.7 - 244632 - - - -1.0157 - 2.419 0.492 - 307.1 1 2 0 -0.0013 12 0 0 0 1.82E+06 2.50E+06 - - - 4.9988 0.9696 221125_WJC_METTL3_EV_vs_WT_F06.13283.13283.3 0.0294 Oct-52 R.ARPATDSFDDYPPR.R "sp|P23588|IF4B_HUMAN,tr|E7EX17|E7EX17_HUMAN,tr|F8VSC7|F8VSC7_HUMAN,tr|F8W0K0|F8W0K0_HUMAN,tr|F8VP89|F8VP89_HUMAN" 5 1606.7376 19.02 82603 13283 3 1606.724487 536.5865 Eukaryotic translation initiation factor 4B OS=Homo sapiens OX=9606 GN=EIF4B PE=1 SV=2 4.43 2384.1 - 4.67E+06 - - - -8.1519 - 1.943 0.359 - 130.5 1 2 0 -0.0131 14 0 0 0 5.38E+07 2.83E+06 - - - 4.3041 0.9988 221125_WJC_METTL3_EV_vs_WT_F06.13285.13285.3 5.37E-08 17/44 L.RQSVEADINGLR.R "sp|P13645|K1C10_HUMAN,sp|Q2M2I5|K1C24_HUMAN,sp|P13646|K1C13_HUMAN,tr|A0A1B0GVI3|A0A1B0GVI3_HUMAN,tr|K7EMD9|K7EMD9_HUMAN,tr|K7ERE3|K7ERE3_HUMAN" 6 1356.711 1047.48 82605 13285 3 1356.711316 453.2443 "Keratin, type I cytoskeletal 10 OS=Homo sapiens OX=9606 GN=KRT10 PE=1 SV=6" 6.07 2384.2 - 7.85E+06 - - - 0.2506 - 3.253 0.558 - 640.9 1 1 0 0.0003 12 0 0 0 2.36E+09 2.25E+06 - - - 8.0307 0.9995 221125_WJC_METTL3_EV_vs_WT_F06.13287.13287.3 3.20E-05 Dec-40 K.DR[166.11]VTDALNATR[166.11].A "sp|P10809|CH60_HUMAN,tr|A0A7I2V2X6|A0A7I2V2X6_HUMAN,tr|A0A7I2YQK6|A0A7I2YQK6_HUMAN,tr|A0A7I2V599|A0A7I2V599_HUMAN" 4 1250.6482 1.25 82607 13287 3 1250.648672 417.89 "60 kDa heat shock protein, mitochondrial OS=Homo sapiens OX=9606 GN=HSPD1 PE=1 SV=2" 5.96 2384.3 - 1.16E+06 - - - 0.375 - 2.269 0.373 - 284 1 2 1 0.0005 11 0 0 0 4.78E+08 3.81E+08 - - - 5.0261 0.9995 221125_WJC_METTL3_EV_vs_WT_F06.13288.13288.3 0.00177 14/52 K.VGQEIEVR[166.11]PGIVSK[136.11].D sp|P41091|IF2G_HUMAN 1 1527.874 1.14 82608 13288 3 1527.881507 510.2986 Eukaryotic translation initiation factor 2 subunit 3 OS=Homo sapiens OX=9606 GN=EIF2S3 PE=1 SV=3 6.11 2384.4 - 1.16E+06 - - - 4.9382 - 3.118 0.429 - 304.3 1 2 0 0.0075 14 0 0 0 1.89E+07 1.66E+07 - - - 6.343 0.9949 221125_WJC_METTL3_EV_vs_WT_F06.13290.13290.3 2.46E-05 13/40 K.DRVTDALNATR.A "sp|P10809|CH60_HUMAN,tr|A0A7I2V2X6|A0A7I2V2X6_HUMAN,tr|A0A7I2YQK6|A0A7I2YQK6_HUMAN,tr|A0A7I2V599|A0A7I2V599_HUMAN" 4 1230.6317 1.25 82610 13290 3 1230.638281 411.2178 "60 kDa heat shock protein, mitochondrial OS=Homo sapiens OX=9606 GN=HSPD1 PE=1 SV=2" 5.96 2384.6 - 737620 - - - 5.3777 - 2.387 0.436 - 230.4 1 2 1 0.0066 11 0 0 0 4.76E+08 3.81E+08 - - - 5.8708 1 221125_WJC_METTL3_EV_vs_WT_F06.13291.13291.3 0.0424 17/48 R.SSLYEGLEKPESR.T "sp|Q01814|AT2B2_HUMAN,sp|P20020|AT2B1_HUMAN,tr|E7ERY9|E7ERY9_HUMAN,tr|A0A2R8Y4R4|A0A2R8Y4R4_HUMAN,tr|A0A0U1RQU3|A0A0U1RQU3_HUMAN,tr|H0YHH6|H0YHH6_HUMAN" 6 1493.7362 2.57 82611 13291 3 1493.737349 498.9193 Plasma membrane calcium-transporting ATPase 2 OS=Homo sapiens OX=9606 GN=ATP2B2 PE=1 SV=2 4.78 2384.7 - 732393 - - - 0.7772 - 2.996 0.403 - 469.4 1 2 0 0.0012 13 0 0 0 2.02E+07 7.85E+06 - - - 6.0078 0.9985 221125_WJC_METTL3_EV_vs_WT_F06.13292.13292.3 0.0277 15/56 R.REMEAQQAALDPALK.Q "sp|P39880|CUX1_HUMAN,tr|A0A2R8Y852|A0A2R8Y852_HUMAN,tr|A0A2R8YDI1|A0A2R8YDI1_HUMAN" 3 1669.8458 1.46 82612 13292 3 1669.850342 557.6225 Homeobox protein cut-like 1 OS=Homo sapiens OX=9606 GN=CUX1 PE=1 SV=3 4.68 2384.9 - 499245 - - - 2.747 - 2.224 0.29 - 261.2 1 2 0 0.0046 15 0 0 0 6.03E+06 4.12E+06 - - - 3.8576 0.9997 221125_WJC_METTL3_EV_vs_WT_F06.13293.13293.3 0.0102 16/56 K.R[166.11]IFHTVTTTDDPVIR[166.11].K "sp|O15371|EIF3D_HUMAN,tr|B0QYA5|B0QYA5_HUMAN,tr|B0QYA4|B0QYA4_HUMAN" 3 1789.959 1.57 82613 13293 3 1789.959769 597.6603 Eukaryotic translation initiation factor 3 subunit D OS=Homo sapiens OX=9606 GN=EIF3D PE=1 SV=1 6.75 2385 - 466569 - - - 0.4447 - 2.271 0.316 - 174.2 1 2 0 0.0008 15 0 0 0 1.97E+07 1.26E+07 - - - 4.2031 1 221125_WJC_METTL3_EV_vs_WT_F06.13294.13294.2 5.54E-08 14/30 R.DQEQVELEGESSAPPR.K sp|Q9BW61|DDA1_HUMAN 1 1769.8068 5.79 82614 13294 2 1769.812242 885.9107 DET1- and DDB1-associated protein 1 OS=Homo sapiens OX=9606 GN=DDA1 PE=1 SV=1 3.91 2385.1 - 429100 - - - 3.0823 - 2.923 0.56 - 470.6 1 2 0 0.0055 16 0 0 0 1.53E+07 2.63E+06 - - - 5.8125 0.9958 221125_WJC_METTL3_EV_vs_WT_F06.13296.13296.2 0.000395 26-Aug K.TNETYGKLEAVQYK.T "sp|P01040|CYTA_HUMAN,tr|C9J0E4|C9J0E4_HUMAN" 2 1642.8203 999 82616 13296 2 1642.821583 822.4174 Cystatin-A OS=Homo sapiens OX=9606 GN=CSTA PE=1 SV=1 5.81 2385.4 - 325023 - - - 0.8102 - 1.725 0.423 - 160.7 1 2 1 0.0013 14 0 0 0 6.47E+06 0.00E+00 - - - 3.5331 1 221125_WJC_METTL3_EV_vs_WT_F06.13299.13299.2 2.05E-08 18/22 L.RQSVEADINGLR.R "sp|P13645|K1C10_HUMAN,sp|Q2M2I5|K1C24_HUMAN,sp|P13646|K1C13_HUMAN,tr|A0A1B0GVI3|A0A1B0GVI3_HUMAN,tr|K7EMD9|K7EMD9_HUMAN,tr|K7ERE3|K7ERE3_HUMAN" 6 1356.711 337.92 82617 13299 2 1356.710339 679.3628 "Keratin, type I cytoskeletal 10 OS=Homo sapiens OX=9606 GN=KRT10 PE=1 SV=6" 6.07 2385.8 - 5.71E+06 - - - -0.4695 - 3.279 0.494 - 458.1 1 1 0 -0.0006 12 0 0 0 5.65E+08 1.67E+06 - - - 5.8141 1 221125_WJC_METTL3_EV_vs_WT_F06.13302.13302.3 5.94E-12 23/64 K.R[166.11]PPAAPENTPLVPSGVK[136.11].S sp|P48634|PRC2A_HUMAN 1 1746.9747 1.34 82620 13302 3 1746.974522 583.3322 Protein PRRC2A OS=Homo sapiens OX=9606 GN=PRRC2A PE=1 SV=3 8.75 2386 - 2.49E+06 - - - -0.1242 - 3.507 0.575 - 658.7 1 2 0 -0.0002 17 0 0 0 2.73E+08 2.05E+08 - - - 8.1205 0.9999 221125_WJC_METTL3_EV_vs_WT_F06.13305.13305.3 1.39E-05 14/48 K.GEHPGLSIGDVAK[136.11].K "sp|B2RPK0|HGB1A_HUMAN,sp|P09429|HMGB1_HUMAN,tr|Q5T7C4|Q5T7C4_HUMAN" 3 1286.671 0.29 82623 13305 3 1286.671074 429.8976 Putative high mobility group protein B1-like 1 OS=Homo sapiens OX=9606 GN=HMGB1P1 PE=5 SV=1 5.32 2386.2 - 1.49E+06 - - - 0.0459 - 2.347 0.446 - 307.7 1 2 0 0.0001 13 0 0 0 1.41E+07 4.84E+07 - - - 5.8255 0.9737 221125_WJC_METTL3_EV_vs_WT_F06.13306.13306.3 0.651 Oct-40 K.HPENYDLATLK.W "sp|P78347|GTF2I_HUMAN,sp|Q86UP8|GTD2A_HUMAN,sp|Q6EKJ0|GTD2B_HUMAN,tr|A0A494C1N8|A0A494C1N8_HUMAN,tr|A0A087WW90|A0A087WW90_HUMAN,tr|A0A0D9SF80|A0A0D9SF80_HUMAN,tr|A0A494C0I1|A0A494C0I1_HUMAN,tr|A0A494C1K3|A0A494C1K3_HUMAN" 8 1299.6459 1.43 82624 13306 3 1299.645965 434.2226 General transcription factor II-I OS=Homo sapiens OX=9606 GN=GTF2I PE=1 SV=2 5.32 2386.3 - 996611 - - - 0.0377 - 1.554 0.129 - 140 1 2 0 0 11 0 0 0 4.83E+07 3.39E+07 - - - 1.2305 0.9915 221125_WJC_METTL3_EV_vs_WT_F06.13308.13308.4 0.00982 14/78 K.LKEENFFGPKEEVK.L sp|Q9NZI8|IF2B1_HUMAN 1 1692.8723 0.68 82626 13308 4 1692.871647 424.2253 Insulin-like growth factor 2 mRNA-binding protein 1 OS=Homo sapiens OX=9606 GN=IGF2BP1 PE=1 SV=2 4.95 2386.6 - 769563 - - - -0.3781 - 2.032 0.259 - 108.8 1 2 2 -0.0006 14 0 0 0 1.42E+07 2.10E+07 - - - 1.7382 1 221125_WJC_METTL3_EV_vs_WT_F06.13309.13309.2 3.50E-06 17/36 K.GAEAANVTGPDGVPVEGSR[166.11].Y "sp|P16989|YBOX3_HUMAN,tr|A0A0D9SEI8|A0A0D9SEI8_HUMAN" 2 1791.8627 1.2 82627 13309 2 1791.861057 896.9386 Y-box-binding protein 3 OS=Homo sapiens OX=9606 GN=YBX3 PE=1 SV=4 4.14 2386.7 - 373343 - - - -0.903 - 3.408 0.612 - 734.3 1 2 0 -0.0016 19 0 0 0 1.59E+08 1.32E+08 - - - 6.5752 1 221125_WJC_METTL3_EV_vs_WT_F06.13312.13312.3 1.55E-06 19/48 K.LR[166.11]DLHPDLEGQLK[136.11].E sp|Q9NYU2|UGGG1_HUMAN 1 1550.8536 0.26 82628 13312 3 1550.853038 517.9585 UDP-glucose:glycoprotein glucosyltransferase 1 OS=Homo sapiens OX=9606 GN=UGGT1 PE=1 SV=3 5.38 2387.1 - 3.14E+06 - - - -0.3372 - 3.415 0.562 - 662.5 1 2 1 -0.0005 13 0 0 0 1.01E+07 3.94E+07 - - - 8.1355 0.997 221125_WJC_METTL3_EV_vs_WT_F06.13315.13315.3 0.00731 Jul-44 R.VSDGDWIC[160.03]PDKK.C sp|O95218|ZRAB2_HUMAN 1 1418.65 0.9 82631 13315 3 1418.64845 473.8906 Zinc finger Ran-binding domain-containing protein 2 OS=Homo sapiens OX=9606 GN=ZRANB2 PE=1 SV=2 4.43 2387.3 - 995200 - - - -1.1032 - 1.558 0.254 - 86.6 1 2 0 -0.0016 12 0 0 0 2.78E+07 3.07E+07 - - - 2.6005 1 221125_WJC_METTL3_EV_vs_WT_F06.13316.13316.2 3.13E-07 17/36 K.GAEAANVTGPDGVPVEGSR.Y "sp|P16989|YBOX3_HUMAN,tr|A0A0D9SEI8|A0A0D9SEI8_HUMAN" 2 1781.8544 1.2 82632 13316 2 1781.858025 891.9345 Y-box-binding protein 3 OS=Homo sapiens OX=9606 GN=YBX3 PE=1 SV=4 4.14 2387.4 - 762307 - - - 2.0316 - 3.385 0.64 - 721 1 2 0 0.0036 19 0 0 0 1.59E+08 1.32E+08 - - - 6.7647 0.9986 221125_WJC_METTL3_EV_vs_WT_F06.13321.13321.2 0.000187 13/20 K.DR[166.11]VTDALNATR[166.11].A "sp|P10809|CH60_HUMAN,tr|A0A7I2V2X6|A0A7I2V2X6_HUMAN,tr|A0A7I2YQK6|A0A7I2YQK6_HUMAN,tr|A0A7I2V599|A0A7I2V599_HUMAN" 4 1250.6482 1.26 82635 13321 2 1250.647651 626.3314 "60 kDa heat shock protein, mitochondrial OS=Homo sapiens OX=9606 GN=HSPD1 PE=1 SV=2" 5.96 2388.1 - 2.13E+07 - - - -0.4414 - 2.594 0.429 - 301.2 1 2 1 -0.0006 11 0 0 0 7.05E+08 5.58E+08 - - - 4.7881 0.9991 221125_WJC_METTL3_EV_vs_WT_F06.13322.13322.2 0.000226 16/20 K.DRVTDALNATR.A "sp|P10809|CH60_HUMAN,tr|A0A7I2V2X6|A0A7I2V2X6_HUMAN,tr|A0A7I2YQK6|A0A7I2YQK6_HUMAN,tr|A0A7I2V599|A0A7I2V599_HUMAN" 4 1230.6317 1.26 82636 13322 2 1230.631189 616.3231 "60 kDa heat shock protein, mitochondrial OS=Homo sapiens OX=9606 GN=HSPD1 PE=1 SV=2" 5.96 2388.1 - 2.18E+07 - - - -0.3852 - 2.978 0.495 - 509.6 1 2 1 -0.0005 11 0 0 0 7.02E+08 5.58E+08 - - - 5.649 1 221125_WJC_METTL3_EV_vs_WT_F06.13325.13325.2 0.00111 15/24 R.DALNQATSQVESK.Q "sp|Q9P2E9|RRBP1_HUMAN,tr|A0A087WVV2|A0A087WVV2_HUMAN,tr|F8W7S5|F8W7S5_HUMAN" 3 1389.6736 1.33 82639 13325 2 1389.671994 695.8441 Ribosome-binding protein 1 OS=Homo sapiens OX=9606 GN=RRBP1 PE=1 SV=5 4.37 2388.4 - 1.32E+06 - - - -1.1463 - 3.224 0.504 - 1100 1 2 0 -0.0016 13 0 0 0 1.63E+08 1.23E+08 - - - 5.7675 0.9999 221125_WJC_METTL3_EV_vs_WT_F06.13326.13326.3 0.0129 18/40 R.TK[136.11]IDPSALVQK[136.11].L "sp|Q9NSI2|SLX9_HUMAN,tr|C9JJU7|C9JJU7_HUMAN" 2 1214.7205 1.5 82640 13326 3 1214.719644 405.9141 Ribosome biogenesis protein SLX9 homolog OS=Homo sapiens OX=9606 GN=SLX9 PE=1 SV=2 8.26 2388.5 - 1.28E+06 - - - -0.736 - 2.807 0.458 - 385.7 1 2 1 -0.0009 11 0 0 0 4.68E+08 3.12E+08 - - - 6.5781 0.9807 221125_WJC_METTL3_EV_vs_WT_F06.13327.13327.4 0.0229 15/72 K.LR[166.11]DLHPDLEGQLK[136.11].E sp|Q9NYU2|UGGG1_HUMAN 1 1550.8536 0.27 82641 13327 4 1550.849687 388.7207 UDP-glucose:glycoprotein glucosyltransferase 1 OS=Homo sapiens OX=9606 GN=UGGT1 PE=1 SV=3 5.38 2388.6 - 1.05E+06 - - - -2.498 - 1.932 0.257 - 167.2 1 2 1 -0.0039 13 0 0 0 4.49E+06 1.67E+07 - - - 1.706 1 221125_WJC_METTL3_EV_vs_WT_F06.13328.13328.3 8.19E-07 14/48 K.C[160.03]DSVC[160.03]VNPYHYER.V "sp|Q13485|SMAD4_HUMAN,tr|K7EIU8|K7EIU8_HUMAN,tr|K7EIJ2|K7EIJ2_HUMAN,tr|K7ES96|K7ES96_HUMAN" 4 1697.6926 1.17 82642 13328 3 1697.692946 566.9048 Mothers against decapentaplegic homolog 4 OS=Homo sapiens OX=9606 GN=SMAD4 PE=1 SV=1 5.32 2388.7 - 965702 - - - 0.1885 - 2.556 0.579 - 326.8 1 2 0 0.0003 13 0 0 0 2.51E+07 2.14E+07 - - - 7.5396 1 221125_WJC_METTL3_EV_vs_WT_F06.13330.13330.2 1.62E-06 24-Nov K.K[136.11]PWQLQGEVTAQK[136.11].R "sp|O00566|MPP10_HUMAN,tr|U3KQ48|U3KQ48_HUMAN" 2 1527.838 2.13 82644 13330 2 1527.840081 764.9263 U3 small nucleolar ribonucleoprotein protein MPP10 OS=Homo sapiens OX=9606 GN=MPHOSPH10 PE=1 SV=2 8.59 2389 - 293355 - - - 1.3444 - 2.935 0.535 - 393.5 1 2 0 0.0021 13 0 0 0 8.36E+06 3.93E+06 - - - 5.7553 0.9698 221125_WJC_METTL3_EV_vs_WT_F06.13332.13332.2 1.33 14-Jul K.GITLSVRP.- tr|A0A075B6Z2|A0A075B6Z2_HUMAN 1 841.5022 931.57 82645 13332 2 841.501809 421.7584 T cell receptor alpha joining 56 (Fragment) OS=Homo sapiens OX=9606 GN=TRAJ56 PE=4 SV=1 9.75 2389.2 - 5.13E+06 - - - -0.4076 - 1.333 0.017 - 181.9 2 2 0 -0.0003 8 0 0 0 4.94E+08 5.31E+05 - - - -0.1011 0.9997 221125_WJC_METTL3_EV_vs_WT_F06.13336.13336.3 0.00124 17/40 R.TKIDPSALVQK.L "sp|Q9NSI2|SLX9_HUMAN,tr|C9JJU7|C9JJU7_HUMAN" 2 1198.6921 1.5 82648 13336 3 1198.691224 400.5713 Ribosome biogenesis protein SLX9 homolog OS=Homo sapiens OX=9606 GN=SLX9 PE=1 SV=2 8.26 2389.5 - 2.10E+06 - - - -0.7625 - 2.793 0.382 - 400.7 1 2 1 -0.0009 11 0 0 0 4.68E+08 3.12E+08 - - - 5.7165 0.9983 221125_WJC_METTL3_EV_vs_WT_F06.13337.13337.3 2.93 Oct-48 K.GWQDVTATSAYKK.T "sp|P55327|TPD52_HUMAN,tr|H0YC42|H0YC42_HUMAN" 2 1453.7201 1.9 82649 13337 3 1453.723877 485.5807 Tumor protein D52 OS=Homo sapiens OX=9606 GN=TPD52 PE=1 SV=2 8.5 2389.6 - 2.07E+06 - - - 2.5679 - 1.845 0.313 - 129.3 1 2 0 0.0037 13 0 0 0 3.52E+07 1.85E+07 - - - 3.6892 1 221125_WJC_METTL3_EV_vs_WT_F06.13338.13338.3 5.11E-06 14/48 R.TGSSHLISTSSWR.D sp|Q5VT06|CE350_HUMAN 1 1417.695 3.94 82650 13338 3 1417.693732 473.5723 Centrosome-associated protein 350 OS=Homo sapiens OX=9606 GN=CEP350 PE=1 SV=1 9.44 2389.6 - 1.71E+06 - - - -0.8888 - 2.635 0.542 - 414.8 1 2 0 -0.0013 13 0 0 0 4.08E+07 1.04E+07 - - - 7.2093 0.9999 221125_WJC_METTL3_EV_vs_WT_F06.13339.13339.3 0.000177 Sep-44 R.VSDGDWIC[160.03]PDK[136.11]K[136.11].C sp|O95218|ZRAB2_HUMAN 1 1434.6784 0.98 82651 13339 3 1434.676707 479.2334 Zinc finger Ran-binding domain-containing protein 2 OS=Homo sapiens OX=9606 GN=ZRANB2 PE=1 SV=2 4.43 2389.7 - 1.39E+06 - - - -1.1905 - 2.08 0.442 - 146.4 1 2 0 -0.0017 12 0 0 0 2.74E+07 2.79E+07 - - - 5.4974 0.9996 221125_WJC_METTL3_EV_vs_WT_F06.13340.13340.2 0.00223 24-Oct R.IFAISQQQQQQSK.S sp|Q9UL01|DSE_HUMAN 1 1532.7947 1.62 82652 13340 2 1532.79667 767.4046 Dermatan-sulfate epimerase OS=Homo sapiens OX=9606 GN=DSE PE=1 SV=1 8.75 2389.8 - 280740 - - - 1.2813 - 2.205 0.35 - 143.6 1 2 0 0.002 13 0 0 0 2.79E+06 1.72E+06 - - - 3.6549 0.9999 221125_WJC_METTL3_EV_vs_WT_F06.13349.13349.2 1.29E-06 20-Dec R.NISHYEEQLVK[136.11].M "sp|P13861|KAP2_HUMAN,tr|H7C330|H7C330_HUMAN" 2 1366.6972 0.05 82659 13349 2 1366.697908 684.3559 cAMP-dependent protein kinase type II-alpha regulatory subunit OS=Homo sapiens OX=9606 GN=PRKAR2A PE=1 SV=2 5.4 2390.8 - 375402 - - - 0.4961 - 2.296 0.521 - 406.8 1 2 0 0.0007 11 0 0 0 1.79E+05 3.73E+06 - - - 5.1374 0.999 221125_WJC_METTL3_EV_vs_WT_F06.13350.13350.2 9.79E-05 24-Nov K.EGLELPEDEEEK[136.11]K[136.11].K "sp|Q58FG0|HS905_HUMAN,sp|P08238|HS90B_HUMAN,sp|Q58FF6|H90B4_HUMAN,sp|Q58FF7|H90B3_HUMAN,sp|P07900|HS90A_HUMAN" 5 1559.7537 0.94 82660 13350 2 1559.752506 780.8842 Putative heat shock protein HSP 90-alpha A5 OS=Homo sapiens OX=9606 GN=HSP90AA5P PE=2 SV=1 4.06 2390.9 - 337533 - - - -0.7963 - 2.057 0.217 - 176.4 1 2 0 -0.0012 13 0 0 0 5.04E+06 5.37E+06 - - - 2.4945 0.9991 221125_WJC_METTL3_EV_vs_WT_F06.13354.13354.3 0.00191 15/48 K.LQLLEEKTDEDEK.T sp|Q8IX12|CCAR1_HUMAN 1 1588.7832 4.33 82662 13354 3 1588.782774 530.6017 Cell division cycle and apoptosis regulator protein 1 OS=Homo sapiens OX=9606 GN=CCAR1 PE=1 SV=2 4.08 2391.3 - 3.61E+06 - - - -0.2669 - 2.043 0.368 - 275.9 1 2 1 -0.0004 13 0 0 0 6.20E+07 1.43E+07 - - - 4.5797 1 221125_WJC_METTL3_EV_vs_WT_F06.13355.13355.3 1.01E-06 15/48 K.KPWQLQGEVTAQK.R "sp|O00566|MPP10_HUMAN,tr|U3KQ48|U3KQ48_HUMAN" 2 1511.8096 1.24 82663 13355 3 1511.811994 504.9438 U3 small nucleolar ribonucleoprotein protein MPP10 OS=Homo sapiens OX=9606 GN=MPHOSPH10 PE=1 SV=2 8.59 2391.4 - 4.20E+06 - - - 1.5657 - 3.026 0.562 - 471.1 1 2 0 0.0024 13 0 0 0 6.70E+07 5.40E+07 - - - 7.8071 0.9999 221125_WJC_METTL3_EV_vs_WT_F06.13358.13358.3 0.0015 Dec-44 R.GSAVHQLSEELR.C "sp|P58107|EPIPL_HUMAN,sp|P58107|EPIPL_HUMAN,sp|P58107|EPIPL_HUMAN,sp|P58107|EPIPL_HUMAN,sp|P58107|EPIPL_HUMAN,tr|A0A075B730|A0A075B730_HUMAN,tr|A0A075B730|A0A075B730_HUMAN,tr|A0A075B730|A0A075B730_HUMAN,tr|A0A075B730|A0A075B730_HUMAN,tr|A0A075B730|A0A075B730_HUMAN" 10 1324.6735 1.72 82666 13358 3 1324.673806 442.5651 Epiplakin OS=Homo sapiens OX=9606 GN=EPPK1 PE=1 SV=3 5.4 2391.5 - 2.62E+06 - - - 0.2099 - 1.972 0.417 - 171.6 1 2 0 0.0003 12 0 0 0 1.53E+08 8.91E+07 - - - 5.0713 0.9996 221125_WJC_METTL3_EV_vs_WT_F06.13361.13361.3 0.000206 14/48 R.EEGRYDEEVEVYR.H "sp|Q5SNT2|TM201_HUMAN,tr|H0Y4R5|H0Y4R5_HUMAN" 2 1671.7376 1.05 82669 13361 3 1671.739896 558.2532 Transmembrane protein 201 OS=Homo sapiens OX=9606 GN=TMEM201 PE=1 SV=1 4.14 2391.8 - 754827 - - - 1.3471 - 2.163 0.44 - 251.6 1 2 1 0.0023 13 0 0 0 1.10E+07 1.05E+07 - - - 5.5367 1 221125_WJC_METTL3_EV_vs_WT_F06.13362.13362.2 1.31E-12 17/34 K.SGGGFGPDPGSGTTVPAR.R sp|Q9H4L4|SENP3_HUMAN 1 1615.759 1.01 82670 13362 2 1615.755985 808.8868 Sentrin-specific protease 3 OS=Homo sapiens OX=9606 GN=SENP3 PE=1 SV=2 5.55 2391.9 - 611509 - - - -1.8957 - 3.029 0.701 - 442.6 1 2 0 -0.0031 18 0 0 0 3.68E+07 3.65E+07 - - - 6.9423 1 221125_WJC_METTL3_EV_vs_WT_F06.13363.13363.2 5.79E-10 17/40 S.SEVPGAAAEGSGGSGVGIGDR.F "sp|Q9NPA0|EMC7_HUMAN,tr|H0YDT8|H0YDT8_HUMAN" 2 1828.8551 0.97 82671 13363 2 1828.857409 915.4348 ER membrane protein complex subunit 7 OS=Homo sapiens OX=9606 GN=EMC7 PE=1 SV=1 4.14 2392.1 - 557262 - - - 1.2439 - 3.109 0.636 - 610.9 1 1 0 0.0023 21 0 0 0 3.28E+07 3.40E+07 - - - 6.5265 0.9257 221125_WJC_METTL3_EV_vs_WT_F06.13364.13364.2 0.443 28-Aug K.HTGPGLLSMANSGPN.T "sp|Q9UNP9|PPIE_HUMAN,tr|E9PEQ6|E9PEQ6_HUMAN,tr|E9PKY5|E9PKY5_HUMAN" 3 1451.6827 - 82672 13364 2 1451.684326 726.8486 Peptidyl-prolyl cis-trans isomerase E OS=Homo sapiens OX=9606 GN=PPIE PE=1 SV=1 6.74 2392.2 - 551837 - - - 1.1118 - 1.589 0.302 - 115.4 1 1 0 0.0016 15 0 0 0 - - - - - 2.4096 1 221125_WJC_METTL3_EV_vs_WT_F06.13367.13367.3 0.000124 Nov-44 K.YSIWC[160.03]STEHGNK.R "sp|Q9BYJ9|YTHD1_HUMAN,sp|Q7Z739|YTHD3_HUMAN,tr|A0A087X0Q1|A0A087X0Q1_HUMAN,tr|A0A024R7W5|A0A024R7W5_HUMAN,tr|A0A087WY31|A0A087WY31_HUMAN" 5 1480.6405 1.52 82673 13367 3 1480.639763 494.5541 YTH domain-containing family protein 1 OS=Homo sapiens OX=9606 GN=YTHDF1 PE=1 SV=1 6.74 2392.6 - 2.42E+06 - - - -0.5065 - 2.204 0.536 - 111 1 2 0 -0.0008 12 0 0 0 1.00E+08 6.62E+07 - - - 6.7062 1 221125_WJC_METTL3_EV_vs_WT_F06.13368.13368.3 0.000305 15/72 K.GAEAANVTGPDGVPVEGSR[166.11].Y "sp|P16989|YBOX3_HUMAN,tr|A0A0D9SEI8|A0A0D9SEI8_HUMAN" 2 1791.8627 1.68 82674 13368 3 1791.862111 598.2948 Y-box-binding protein 3 OS=Homo sapiens OX=9606 GN=YBX3 PE=1 SV=4 4.14 2392.7 - 2.02E+06 - - - -0.3148 - 3.058 0.594 - 170.3 1 2 0 -0.0006 19 0 0 0 1.00E+08 5.96E+07 - - - 7.9085 0.9992 221125_WJC_METTL3_EV_vs_WT_F06.13369.13369.3 0.000693 Aug-44 K.YSIWC[160.03]STEHGNK[136.11].R "sp|Q9BYJ9|YTHD1_HUMAN,sp|Q7Z739|YTHD3_HUMAN,tr|A0A087X0Q1|A0A087X0Q1_HUMAN,tr|A0A024R7W5|A0A024R7W5_HUMAN,tr|A0A087WY31|A0A087WY31_HUMAN" 5 1488.6547 1.52 82675 13369 3 1488.655394 497.2255 YTH domain-containing family protein 1 OS=Homo sapiens OX=9606 GN=YTHDF1 PE=1 SV=1 6.74 2392.7 - 1.99E+06 - - - 0.4575 - 1.578 0.326 - 53.9 1 2 0 0.0007 12 0 0 0 1.00E+08 6.62E+07 - - - 3.4388 1 221125_WJC_METTL3_EV_vs_WT_F06.13387.13387.3 4.59E-07 14/72 K.GAEAANVTGPDGVPVEGSR.Y "sp|P16989|YBOX3_HUMAN,tr|A0A0D9SEI8|A0A0D9SEI8_HUMAN" 2 1781.8544 1.4 82689 13387 3 1781.856256 594.9587 Y-box-binding protein 3 OS=Homo sapiens OX=9606 GN=YBX3 PE=1 SV=4 4.14 2394.6 - 3.56E+06 - - - 1.0388 - 2.764 0.54 - 133.7 1 2 0 0.0019 19 0 0 0 8.30E+07 5.91E+07 - - - 7.0577 0.9817 221125_WJC_METTL3_EV_vs_WT_F06.13390.13390.3 0.149 Sep-36 K.TKFTIENVTR.T sp|Q9NRX1|PNO1_HUMAN 1 1207.6561 0.69 82692 13390 3 1207.65496 403.5593 RNA-binding protein PNO1 OS=Homo sapiens OX=9606 GN=PNO1 PE=1 SV=1 8.41 2394.9 - 652786 - - - -0.9332 - 1.704 0.204 - 117.5 1 2 1 -0.0011 10 0 0 0 1.04E+07 1.51E+07 - - - 2.3706 0.9971 221125_WJC_METTL3_EV_vs_WT_F06.13396.13396.2 0.000198 28-Jul K.EQGPYETYEGSPVSK[136.11].G "sp|P23921|RIR1_HUMAN,tr|E9PL69|E9PL69_HUMAN" 2 1677.7613 0.17 82698 13396 2 1677.754807 839.8879 Ribonucleoside-diphosphate reductase large subunit OS=Homo sapiens OX=9606 GN=RRM1 PE=1 SV=1 4.25 2395.6 - 300381 - - - -3.8975 - 1.657 0.429 - 143.8 1 2 0 -0.0065 15 0 0 0 1.49E+06 9.03E+06 - - - 3.4491 0.9874 221125_WJC_METTL3_EV_vs_WT_F06.13397.13397.2 0.01 Sep-34 F.GLTDDQVSGPPSAPAEDR.S "sp|Q92734|TFG_HUMAN,tr|A0A6Q8PG00|A0A6Q8PG00_HUMAN,tr|A0A6Q8PH89|A0A6Q8PH89_HUMAN,tr|A0A6Q8PG04|A0A6Q8PG04_HUMAN,tr|A0A6Q8PFY7|A0A6Q8PFY7_HUMAN,tr|A0A6Q8PH27|A0A6Q8PH27_HUMAN,tr|A0A6Q8PF40|A0A6Q8PF40_HUMAN,tr|A0A6Q8PGS4|A0A6Q8PGS4_HUMAN,tr|A0A6Q8PFC4|A0A6Q8PFC4_HUMAN" 9 1810.8333 1.41 82699 13397 2 1810.833239 906.4239 Protein TFG OS=Homo sapiens OX=9606 GN=TFG PE=1 SV=2 3.84 2395.8 - 246310 - - - -0.0536 - 1.929 0.452 - 186.5 1 1 0 -0.0001 18 0 0 0 2.20E+06 1.56E+06 - - - 3.9947 0.9445 221125_WJC_METTL3_EV_vs_WT_F06.13399.13399.3 0.255 Sep-48 K.EGLELPEDEEEKK.K "sp|Q58FG0|HS905_HUMAN,sp|P08238|HS90B_HUMAN,sp|Q58FF6|H90B4_HUMAN,sp|Q58FF7|H90B3_HUMAN,sp|P07900|HS90A_HUMAN" 5 1543.7253 0.86 82700 13399 3 1543.725101 515.5824 Putative heat shock protein HSP 90-alpha A5 OS=Homo sapiens OX=9606 GN=HSP90AA5P PE=2 SV=1 4.06 2396 - 4.23E+06 - - - -0.16 - 1.6 0.088 - 84.5 1 2 0 -0.0002 13 0 0 0 8.98E+07 1.05E+08 - - - 0.7954 0.9166 221125_WJC_METTL3_EV_vs_WT_F06.13401.13401.3 0.000885 Sep-52 M.ASHLTSTSLDPYDR.H sp|Q9BWF3|RBM4_HUMAN 1 1561.7372 1.23 82702 13401 3 1561.740078 521.5864 RNA-binding protein 4 OS=Homo sapiens OX=9606 GN=RBM4 PE=1 SV=1 5.21 2396.1 - 2.76E+06 - - - 1.8108 - 2.055 0.302 - 106.2 1 1 0 0.0028 14 0 0 0 5.17E+07 4.18E+07 - - - 3.8204 0.9872 221125_WJC_METTL3_EV_vs_WT_F06.13402.13402.3 0.0366 Dec-56 K.DVDSAYMNKVELQAK.V sp|P12035|K2C3_HUMAN 1 1709.8294 303.83 82703 13402 3 1709.83558 570.9504 "Keratin, type II cytoskeletal 3 OS=Homo sapiens OX=9606 GN=KRT3 PE=1 SV=3" 4.56 2396.2 - 2.05E+06 - - - 3.5933 - 2.2 0.293 - 114.6 1 2 1 0.0061 15 0 0 0 3.59E+08 1.18E+06 - - - 3.8623 1 221125_WJC_METTL3_EV_vs_WT_F06.13405.13405.3 2.70E-06 Nov-52 K.RGPGLYYVDSEGNR.L sp|P28074|PSB5_HUMAN 1 1581.7536 0.68 82706 13405 3 1581.753473 528.2585 Proteasome subunit beta type-5 OS=Homo sapiens OX=9606 GN=PSMB5 PE=1 SV=3 6.07 2396.4 - 942486 - - - -0.0607 - 2.108 0.536 - 134.1 1 2 0 -0.0001 14 0 0 0 3.47E+07 5.10E+07 - - - 6.4977 1 221125_WJC_METTL3_EV_vs_WT_F06.13406.13406.2 2.74E-06 15/30 K.AQGAGVTLPPTPSGSR.T "sp|Q6P996|PDXD1_HUMAN,tr|H3BND4|H3BND4_HUMAN" 2 1494.7791 2 82707 13406 2 1494.778943 748.3968 Pyridoxal-dependent decarboxylase domain-containing protein 1 OS=Homo sapiens OX=9606 GN=PDXDC1 PE=1 SV=2 9.79 2396.6 - 685617 - - - -0.0756 - 3.051 0.547 - 438 1 2 0 -0.0001 16 0 0 0 1.51E+07 7.55E+06 - - - 5.8235 0.9999 221125_WJC_METTL3_EV_vs_WT_F06.13407.13407.3 2.51E-08 17/68 R.NLIATAQAQNQQQTEGVK.T sp|O94864|ST65G_HUMAN 1 1940.9916 1.29 82708 13407 3 1940.998933 648.0045 STAGA complex 65 subunit gamma OS=Homo sapiens OX=9606 GN=SUPT7L PE=1 SV=1 6 2396.7 - 683333 - - - 3.7945 - 2.864 0.519 - 273.4 1 2 0 0.0074 18 0 0 0 2.34E+07 1.82E+07 - - - 6.9444 0.9957 221125_WJC_METTL3_EV_vs_WT_F06.13408.13408.3 0.152 Jul-32 K.HAYSWDINR.A sp|Q8WUM0|NU133_HUMAN 1 1160.5363 1.3 82709 13408 3 1160.53632 387.8527 Nuclear pore complex protein Nup133 OS=Homo sapiens OX=9606 GN=NUP133 PE=1 SV=2 6.74 2396.8 - 655233 - - - 0.0121 - 1.509 0.229 - 94.8 1 2 0 0 9 0 0 0 8.11E+06 6.24E+06 - - - 2.3331 0.998 221125_WJC_METTL3_EV_vs_WT_F06.13409.13409.2 0.000106 24-Dec R.DIK[136.11]DTTVGTLSQR[166.11].L sp|P51665|PSMD7_HUMAN 1 1450.7746 0.58 82710 13409 2 1450.776576 726.3946 26S proteasome non-ATPase regulatory subunit 7 OS=Homo sapiens OX=9606 GN=PSMD7 PE=1 SV=2 5.96 2397 - 615163 - - - 1.3331 - 2.178 0.535 - 289.3 1 2 1 0.0019 13 0 0 0 3.83E+06 6.57E+06 - - - 4.9897 0.9995 221125_WJC_METTL3_EV_vs_WT_F06.13411.13411.2 0.0836 22-Nov K.YSIWC[160.03]STEHGNK[136.11].R "sp|Q9BYJ9|YTHD1_HUMAN,sp|Q7Z739|YTHD3_HUMAN,tr|A0A087X0Q1|A0A087X0Q1_HUMAN,tr|A0A024R7W5|A0A024R7W5_HUMAN,tr|A0A087WY31|A0A087WY31_HUMAN" 5 1488.6547 1.98 82712 13411 2 1488.658378 745.3346 YTH domain-containing family protein 1 OS=Homo sapiens OX=9606 GN=YTHDF1 PE=1 SV=1 6.74 2397.2 - 350104 - - - 2.462 - 2.065 0.485 - 484.2 1 2 0 0.0037 12 0 0 0 6.32E+06 3.20E+06 - - - 4.53 0.9988 221125_WJC_METTL3_EV_vs_WT_F06.13415.13415.2 0.00475 15/20 R.TK[136.11]IDPSALVQK[136.11].L "sp|Q9NSI2|SLX9_HUMAN,tr|C9JJU7|C9JJU7_HUMAN" 2 1214.7205 1.63 82714 13415 2 1214.720867 608.3675 Ribosome biogenesis protein SLX9 homolog OS=Homo sapiens OX=9606 GN=SLX9 PE=1 SV=2 8.26 2397.6 - 3.63E+06 - - - 0.2708 - 2.611 0.478 - 587.7 1 2 1 0.0003 11 0 0 0 2.06E+08 1.26E+08 - - - 5.1677 0.9242 221125_WJC_METTL3_EV_vs_WT_F06.13417.13417.3 0.0173 Sep-52 M.ASHLTSTSLDPYDR[166.11].H sp|Q9BWF3|RBM4_HUMAN 1 1571.7455 1.24 82716 13417 3 1571.746087 524.9224 RNA-binding protein 4 OS=Homo sapiens OX=9606 GN=RBM4 PE=1 SV=1 5.21 2397.7 - 3.21E+06 - - - 0.3607 - 1.792 0.305 - 89.9 1 1 0 0.0006 14 0 0 0 5.20E+07 4.18E+07 - - - 3.4905 1 221125_WJC_METTL3_EV_vs_WT_F06.13418.13418.3 1.77E-05 15/60 K.LQQAAQQHIQQQLLAK[136.11].Q sp|Q9UKJ3|GPTC8_HUMAN 1 1853.0363 0.87 82717 13418 3 1853.035302 618.686 G patch domain-containing protein 8 OS=Homo sapiens OX=9606 GN=GPATCH8 PE=1 SV=2 8.76 2397.8 - 3.13E+06 - - - -0.5278 - 3.012 0.54 - 285.9 1 2 0 -0.001 16 0 0 0 1.14E+08 1.31E+08 - - - 7.3893 0.9988 221125_WJC_METTL3_EV_vs_WT_F06.13419.13419.2 1.03E-06 14/22 R.GSAVHQLSEELR[166.11].C "sp|P58107|EPIPL_HUMAN,sp|P58107|EPIPL_HUMAN,sp|P58107|EPIPL_HUMAN,sp|P58107|EPIPL_HUMAN,sp|P58107|EPIPL_HUMAN,tr|A0A075B730|A0A075B730_HUMAN,tr|A0A075B730|A0A075B730_HUMAN,tr|A0A075B730|A0A075B730_HUMAN,tr|A0A075B730|A0A075B730_HUMAN,tr|A0A075B730|A0A075B730_HUMAN" 10 1334.6818 2.36 82718 13419 2 1334.687627 668.3482 Epiplakin OS=Homo sapiens OX=9606 GN=EPPK1 PE=1 SV=3 5.4 2397.8 - 2.98E+06 - - - 4.3673 - 2.531 0.53 - 870.1 1 2 0 0.0058 12 0 0 0 7.22E+07 3.06E+07 - - - 5.3971 0.9996 221125_WJC_METTL3_EV_vs_WT_F06.13421.13421.3 0.0123 Nov-44 K.GKPDLNTALPVR.Q "sp|O95983|MBD3_HUMAN,tr|A0A087X1H1|A0A087X1H1_HUMAN,tr|K7EIE8|K7EIE8_HUMAN,tr|A0A087WT34|A0A087WT34_HUMAN,tr|A0A0A0MTS6|A0A0A0MTS6_HUMAN" 5 1279.7248 1.56 82720 13421 3 1279.726127 427.5822 Methyl-CpG-binding domain protein 3 OS=Homo sapiens OX=9606 GN=MBD3 PE=1 SV=1 8.75 2398 - 1.63E+06 - - - 1.0096 - 2.294 0.297 - 160.1 1 2 0 0.0013 12 0 0 0 3.59E+07 2.30E+07 - - - 4.1524 0.9996 221125_WJC_METTL3_EV_vs_WT_F06.13422.13422.3 0.000582 Oct-44 K.GK[136.11]PDLNTALPVR[166.11].Q "sp|O95983|MBD3_HUMAN,tr|A0A087X1H1|A0A087X1H1_HUMAN,tr|K7EIE8|K7EIE8_HUMAN,tr|A0A087WT34|A0A087WT34_HUMAN,tr|A0A0A0MTS6|A0A0A0MTS6_HUMAN" 5 1297.7473 0.87 82721 13422 3 1297.748795 433.5897 Methyl-CpG-binding domain protein 3 OS=Homo sapiens OX=9606 GN=MBD3 PE=1 SV=1 8.75 2398.1 - 1.08E+06 - - - 1.1481 - 2.44 0.278 - 150.9 1 2 0 0.0015 12 0 0 0 2.12E+07 2.45E+07 - - - 4.1115 0.9998 221125_WJC_METTL3_EV_vs_WT_F06.13423.13423.2 2.67E-08 22-Dec K.YSIWC[160.03]STEHGNK.R "sp|Q9BYJ9|YTHD1_HUMAN,sp|Q7Z739|YTHD3_HUMAN,tr|A0A087X0Q1|A0A087X0Q1_HUMAN,tr|A0A024R7W5|A0A024R7W5_HUMAN,tr|A0A087WY31|A0A087WY31_HUMAN" 5 1480.6405 1.98 82722 13423 2 1480.637325 741.3275 YTH domain-containing family protein 1 OS=Homo sapiens OX=9606 GN=YTHDF1 PE=1 SV=1 6.74 2398.2 - 473243 - - - -2.1531 - 2.165 0.566 - 622.7 1 2 0 -0.0032 12 0 0 0 6.32E+06 3.20E+06 - - - 5.2528 1 221125_WJC_METTL3_EV_vs_WT_F06.13424.13424.2 1.66E-09 17/34 R.NLIATAQAQNQQQTEGVK.T sp|O94864|ST65G_HUMAN 1 1940.9916 1.61 82723 13424 2 1940.995837 971.5031 STAGA complex 65 subunit gamma OS=Homo sapiens OX=9606 GN=SUPT7L PE=1 SV=1 6 2398.3 - 311533 - - - 2.1994 - 3.628 0.685 - 865 1 2 0 0.0043 18 0 0 0 5.63E+06 3.50E+06 - - - 7.2674 0.9982 221125_WJC_METTL3_EV_vs_WT_F06.13428.13428.2 0.000119 15/20 R.TKIDPSALVQK.L "sp|Q9NSI2|SLX9_HUMAN,tr|C9JJU7|C9JJU7_HUMAN" 2 1198.6921 1.63 82725 13428 2 1198.693167 600.3533 Ribosome biogenesis protein SLX9 homolog OS=Homo sapiens OX=9606 GN=SLX9 PE=1 SV=2 8.26 2398.9 - 6.29E+06 - - - 0.8584 - 2.583 0.423 - 585.2 1 2 1 0.001 11 0 0 0 2.06E+08 1.26E+08 - - - 4.7321 1 221125_WJC_METTL3_EV_vs_WT_F06.13429.13429.3 2.28E-05 13/68 R.NLIATAQAQNQQQTEGVK[136.11].T sp|O94864|ST65G_HUMAN 1 1949.0058 1.29 82726 13429 3 1949.007651 650.6759 STAGA complex 65 subunit gamma OS=Homo sapiens OX=9606 GN=SUPT7L PE=1 SV=1 6 2398.9 - 1.62E+06 - - - 0.9661 - 2.547 0.479 - 129.2 1 2 0 0.0019 18 0 0 0 2.34E+07 1.82E+07 - - - 6.2079 0.9999 221125_WJC_METTL3_EV_vs_WT_F06.13430.13430.3 0.000186 13/60 K.LQQAAQQHIQQQLLAK.Q sp|Q9UKJ3|GPTC8_HUMAN 1 1845.0221 0.87 82727 13430 3 1845.025042 616.0146 G patch domain-containing protein 8 OS=Homo sapiens OX=9606 GN=GPATCH8 PE=1 SV=2 8.76 2399 - 3.96E+06 - - - 1.6054 - 2.394 0.434 - 100 1 2 0 0.003 16 0 0 0 1.14E+08 1.31E+08 - - - 5.6178 1 221125_WJC_METTL3_EV_vs_WT_F06.13432.13432.3 9.59E-06 15/48 R.K[136.11]ASGPPVSELITK[136.11].A "sp|P10412|H14_HUMAN,sp|P16403|H12_HUMAN,sp|P16402|H13_HUMAN" 3 1341.7839 0.72 82729 13432 3 1341.784713 448.2686 Histone H1.4 OS=Homo sapiens OX=9606 GN=H1-4 PE=1 SV=2 8.59 2399.1 - 1.10E+06 - - - 0.6305 - 3.139 0.517 - 335.9 1 2 0 0.0008 13 0 0 0 7.41E+07 1.03E+08 - - - 7.4053 1 221125_WJC_METTL3_EV_vs_WT_F06.13433.13433.2 2.18E-08 14/26 K.ADSWVEKEEPAPSN.- "sp|Q8N163|CCAR2_HUMAN,tr|H0YB24|H0YB24_HUMAN" 2 1557.6947 0.97 82730 13433 2 1557.697444 779.8546 Cell cycle and apoptosis regulator protein 2 OS=Homo sapiens OX=9606 GN=CCAR2 PE=1 SV=2 4 2399.3 - 861357 - - - 1.7507 - 2.768 0.64 - 406.4 1 2 1 0.0027 14 0 0 0 1.53E+07 1.58E+07 - - - 6.3221 1 221125_WJC_METTL3_EV_vs_WT_F06.13435.13435.2 4.47E-09 14/26 K.ADSWVEK[136.11]EEPAPSN.- "sp|Q8N163|CCAR2_HUMAN,tr|H0YB24|H0YB24_HUMAN" 2 1565.7089 0.95 82732 13435 2 1565.705645 783.8617 Cell cycle and apoptosis regulator protein 2 OS=Homo sapiens OX=9606 GN=CCAR2 PE=1 SV=2 4 2399.5 - 657345 - - - -2.0898 - 2.909 0.699 - 384.4 1 2 1 -0.0033 14 0 0 0 1.53E+07 1.60E+07 - - - 6.8824 0.9999 221125_WJC_METTL3_EV_vs_WT_F06.13437.13437.3 3.14E-07 16/64 K.IDEAESLNDEELEEKEK.L sp|O60264|SMCA5_HUMAN 1 2018.9168 2.19 82734 13437 3 2018.918067 673.9795 SWI\SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A member 5 OS=Homo sapiens OX=9606 GN=SMARCA5 PE=1 SV=1 3.89 2399.7 - 432634 - - - 0.632 - 3.061 0.53 - 257.4 1 2 1 0.0013 17 0 0 0 1.46E+07 6.66E+06 - - - 7.2749 0.9999 221125_WJC_METTL3_EV_vs_WT_F06.13446.13446.3 0.00102 18/48 R.RATVVVGDLHPLR.D "sp|Q9NSI2|SLX9_HUMAN,tr|C9JJU7|C9JJU7_HUMAN" 2 1431.831 1.39 82741 13446 3 1431.832049 478.2843 Ribosome biogenesis protein SLX9 homolog OS=Homo sapiens OX=9606 GN=SLX9 PE=1 SV=2 9.61 2400.7 - 3.02E+06 - - - 0.7103 - 3.063 0.344 - 509.5 1 2 0 0.001 13 0 0 0 1.63E+08 1.17E+08 - - - 5.41 0.9656 221125_WJC_METTL3_EV_vs_WT_F06.13448.13448.3 0.196 Aug-52 K.SDIGQYTC[160.03]DC[160.03]GTDK[136.11].T "sp|Q8WZ42|TITIN_HUMAN,tr|A0A0A0MTS7|A0A0A0MTS7_HUMAN,tr|A0A0A0MRA3|A0A0A0MRA3_HUMAN" 3 1626.6381 0.08 82743 13448 3 1626.629661 543.22 Titin OS=Homo sapiens OX=9606 GN=TTN PE=1 SV=4 3.93 2400.8 - 2.53E+06 - - - -5.2107 - 1.188 0.347 - 53.2 1 2 0 -0.0085 14 0 0 0 3.38E+06 4.31E+07 - - - 2.8642 1 221125_WJC_METTL3_EV_vs_WT_F06.13449.13449.3 8.22E-05 15/48 R.R[166.11]ATVVVGDLHPLR[166.11].D "sp|Q9NSI2|SLX9_HUMAN,tr|C9JJU7|C9JJU7_HUMAN" 2 1451.8476 1.37 82744 13449 3 1451.846883 484.9565 Ribosome biogenesis protein SLX9 homolog OS=Homo sapiens OX=9606 GN=SLX9 PE=1 SV=2 9.61 2400.9 - 2.43E+06 - - - -0.4746 - 2.69 0.44 - 385.3 1 2 0 -0.0007 13 0 0 0 1.63E+08 1.19E+08 - - - 6.1283 0.9996 221125_WJC_METTL3_EV_vs_WT_F06.13450.13450.3 3.56E-07 Dec-52 R.FTQDTQPHYIYSPR[166.11].E "sp|Q14204|DYHC1_HUMAN,tr|A0A7P0T8N2|A0A7P0T8N2_HUMAN,tr|A0A7P0T9C4|A0A7P0T9C4_HUMAN,tr|A0A7P0TBJ7|A0A7P0TBJ7_HUMAN,tr|A0A804HHY6|A0A804HHY6_HUMAN,tr|A0A7P0T9K2|A0A7P0T9K2_HUMAN,tr|A0A7P0TB64|A0A7P0TB64_HUMAN,tr|A0A2R8Y706|A0A2R8Y706_HUMAN,tr|A0A7P0T916|A0A7P0T916_HUMAN,tr|A0A7P0TB75|A0A7P0TB75_HUMAN,tr|A0A7P0T8W5|A0A7P0T8W5_HUMAN,tr|A0A7P0TAF3|A0A7P0TAF3_HUMAN,tr|A0A7P0T9F1|A0A7P0T9F1_HUMAN,tr|A0A7P0TAW9|A0A7P0TAW9_HUMAN,tr|A0A7P0TA13|A0A7P0TA13_HUMAN,tr|A0A7P0TAV5|A0A7P0TAV5_HUMAN,tr|A0A7P0T7V5|A0A7P0T7V5_HUMAN,tr|A0A7P0T9R4|A0A7P0T9R4_HUMAN,tr|A0A2R8Y5T0|A0A2R8Y5T0_HUMAN,tr|A0A7P0T990|A0A7P0T990_HUMAN,tr|A0A2R8YFZ7|A0A2R8YFZ7_HUMAN,tr|A0A7P0T825|A0A7P0T825_HUMAN,tr|A0A2R8Y6H2|A0A2R8Y6H2_HUMAN,tr|A0A7P0TAM4|A0A7P0TAM4_HUMAN" 24 1761.835 0.93 82745 13450 3 1761.843557 588.2856 Cytoplasmic dynein 1 heavy chain 1 OS=Homo sapiens OX=9606 GN=DYNC1H1 PE=1 SV=5 6.74 2400.9 - 1.65E+06 - - - 4.8546 - 2.495 0.517 - 182.7 1 2 0 0.0086 14 0 0 0 3.20E+07 3.43E+07 - - - 6.7314 0.8844 221125_WJC_METTL3_EV_vs_WT_F06.13452.13452.3 0.427 Aug-44 K.SSLTQHSWQSLK[136.11].D "sp|Q9NYB0|TE2IP_HUMAN,tr|A0A590UJT3|A0A590UJT3_HUMAN" 2 1408.719 0.49 82747 13452 3 1408.717045 470.5803 Telomeric repeat-binding factor 2-interacting protein 1 OS=Homo sapiens OX=9606 GN=TERF2IP PE=1 SV=1 8.49 2401 - 1.24E+06 - - - -1.4077 - 1.612 0.067 - 55.6 2 2 0 -0.002 12 0 0 0 1.22E+07 2.49E+07 - - - 0.4706 0.9999 221125_WJC_METTL3_EV_vs_WT_F06.13456.13456.3 3.91E-05 16/56 R.LGLHQQGSEPSYLDR.T "sp|Q9BV38|WDR18_HUMAN,tr|U3KQC1|U3KQC1_HUMAN,tr|A0A0A0MQU0|A0A0A0MQU0_HUMAN" 3 1698.8325 0.61 82751 13456 3 1698.833726 567.2848 WD repeat-containing protein 18 OS=Homo sapiens OX=9606 GN=WDR18 PE=1 SV=2 5.32 2401.5 - 808986 - - - 0.6934 - 2.492 0.428 - 397 1 2 0 0.0012 15 0 0 0 1.98E+07 3.25E+07 - - - 5.694 1 221125_WJC_METTL3_EV_vs_WT_F06.13460.13460.3 1.45E-07 16/56 R.GISEETTTGVHNLYK[136.11].M sp|P23526|SAHH_HUMAN 1 1655.8246 0.99 82753 13460 3 1655.827751 552.9488 Adenosylhomocysteinase OS=Homo sapiens OX=9606 GN=AHCY PE=1 SV=4 5.4 2401.9 - 1.60E+06 - - - 1.8939 - 3.2 0.563 - 201.7 1 2 0 0.0031 15 0 0 0 3.62E+07 3.65E+07 - - - 7.8511 1 221125_WJC_METTL3_EV_vs_WT_F06.13463.13463.3 8.10E-07 15/56 R.GISEETTTGVHNLYK.M sp|P23526|SAHH_HUMAN 1 1647.8104 0.99 82756 13463 3 1647.812805 550.2774 Adenosylhomocysteinase OS=Homo sapiens OX=9606 GN=AHCY PE=1 SV=4 5.4 2402.1 - 1.63E+06 - - - 1.4504 - 2.891 0.573 - 191 1 2 0 0.0024 15 0 0 0 3.62E+07 3.65E+07 - - - 7.6978 1 221125_WJC_METTL3_EV_vs_WT_F06.13465.13465.3 1.10E-05 14/72 K.VAPSWPESHSSADSASLAK.K sp|Q7LBC6|KDM3B_HUMAN 1 1925.9119 1.47 82758 13465 3 1925.914657 642.9779 Lysine-specific demethylase 3B OS=Homo sapiens OX=9606 GN=KDM3B PE=1 SV=2 5.32 2402.3 - 899896 - - - 1.4211 - 2.773 0.543 - 159.1 1 2 0 0.0027 19 0 0 0 1.18E+07 8.05E+06 - - - 7.0989 0.9984 221125_WJC_METTL3_EV_vs_WT_F06.13466.13466.3 0.00188 Nov-48 K.DK[136.11]FTDSAIAMNSK[136.11].V "sp|Q8WWM7|ATX2L_HUMAN,tr|H3BSK9|H3BSK9_HUMAN,tr|H3BUE3|H3BUE3_HUMAN,tr|H3BUF6|H3BUF6_HUMAN" 4 1442.7046 0.76 82759 13466 3 1442.707111 481.9088 Ataxin-2-like protein OS=Homo sapiens OX=9606 GN=ATXN2L PE=1 SV=2 5.96 2402.4 - 656333 - - - 1.7197 - 1.966 0.372 - 179.5 1 2 1 0.0025 13 0 0 0 6.09E+07 7.98E+07 - - - 4.5196 0.9996 221125_WJC_METTL3_EV_vs_WT_F06.13467.13467.2 0.000922 30-Jul K.AQGAGVTLPPTPSGSR[166.11].T "sp|Q6P996|PDXD1_HUMAN,tr|H3BND4|H3BND4_HUMAN" 2 1504.7873 1.93 82760 13467 2 1504.788615 753.4009 Pyridoxal-dependent decarboxylase domain-containing protein 1 OS=Homo sapiens OX=9606 GN=PDXDC1 PE=1 SV=2 9.79 2402.5 - 232236 - - - 0.8566 - 1.645 0.423 - 95.4 1 2 0 0.0013 16 0 0 0 9.77E+06 5.05E+06 - - - 3.3886 1 221125_WJC_METTL3_EV_vs_WT_F06.13468.13468.2 1.11E-07 14/30 K.LQQAAQQHIQQQLLAK.Q sp|Q9UKJ3|GPTC8_HUMAN 1 1845.0221 0.85 82761 13468 2 1845.023405 923.5183 G patch domain-containing protein 8 OS=Homo sapiens OX=9606 GN=GPATCH8 PE=1 SV=2 8.76 2402.6 - 184868 - - - 0.7181 - 3.028 0.56 - 405.8 1 2 0 0.0013 16 0 0 0 1.90E+06 2.23E+06 - - - 5.9006 0.9999 221125_WJC_METTL3_EV_vs_WT_F06.13472.13472.3 0.00012 Dec-52 R.FTQDTQPHYIYSPR.E "sp|Q14204|DYHC1_HUMAN,tr|A0A7P0T8N2|A0A7P0T8N2_HUMAN,tr|A0A7P0T9C4|A0A7P0T9C4_HUMAN,tr|A0A7P0TBJ7|A0A7P0TBJ7_HUMAN,tr|A0A804HHY6|A0A804HHY6_HUMAN,tr|A0A7P0T9K2|A0A7P0T9K2_HUMAN,tr|A0A7P0TB64|A0A7P0TB64_HUMAN,tr|A0A2R8Y706|A0A2R8Y706_HUMAN,tr|A0A7P0T916|A0A7P0T916_HUMAN,tr|A0A7P0TB75|A0A7P0TB75_HUMAN,tr|A0A7P0T8W5|A0A7P0T8W5_HUMAN,tr|A0A7P0TAF3|A0A7P0TAF3_HUMAN,tr|A0A7P0T9F1|A0A7P0T9F1_HUMAN,tr|A0A7P0TAW9|A0A7P0TAW9_HUMAN,tr|A0A7P0TA13|A0A7P0TA13_HUMAN,tr|A0A7P0TAV5|A0A7P0TAV5_HUMAN,tr|A0A7P0T7V5|A0A7P0T7V5_HUMAN,tr|A0A7P0T9R4|A0A7P0T9R4_HUMAN,tr|A0A2R8Y5T0|A0A2R8Y5T0_HUMAN,tr|A0A7P0T990|A0A7P0T990_HUMAN,tr|A0A2R8YFZ7|A0A2R8YFZ7_HUMAN,tr|A0A7P0T825|A0A7P0T825_HUMAN,tr|A0A2R8Y6H2|A0A2R8Y6H2_HUMAN,tr|A0A7P0TAM4|A0A7P0TAM4_HUMAN" 24 1751.8267 0.53 82763 13472 3 1751.825754 584.9495 Cytoplasmic dynein 1 heavy chain 1 OS=Homo sapiens OX=9606 GN=DYNC1H1 PE=1 SV=5 6.74 2403.1 - 1.99E+06 - - - -0.5594 - 2.043 0.453 - 145.4 1 2 0 -0.001 14 0 0 0 3.54E+07 6.73E+07 - - - 5.4888 0.9999 221125_WJC_METTL3_EV_vs_WT_F06.13474.13474.3 5.47E-05 14/48 R.EDPNLVPSISNK[136.11]R[166.11].L sp|P10606|COX5B_HUMAN 1 1485.7906 1.7 82765 13474 3 1485.794233 496.2708 "Cytochrome c oxidase subunit 5B, mitochondrial OS=Homo sapiens OX=9606 GN=COX5B PE=1 SV=2" 6.17 2403.2 - 1.28E+06 - - - 2.427 - 2.219 0.469 - 245.2 1 2 0 0.0036 13 0 0 0 5.04E+07 2.97E+07 - - - 5.9289 0.9999 221125_WJC_METTL3_EV_vs_WT_F06.13476.13476.2 6.24E-07 14/22 K.TGNLGNVVHIER.F "sp|Q6P5R6|RL22L_HUMAN,tr|H0Y8C2|H0Y8C2_HUMAN,tr|C9JYQ9|C9JYQ9_HUMAN" 3 1307.6946 1.05 82767 13476 2 1307.695895 654.8546 60S ribosomal protein L22-like 1 OS=Homo sapiens OX=9606 GN=RPL22L1 PE=1 SV=2 6.41 2403.5 - 577841 - - - 0.9918 - 2.872 0.517 - 699.8 1 2 0 0.0013 12 0 0 0 3.38E+07 3.22E+07 - - - 5.6351 0.9971 221125_WJC_METTL3_EV_vs_WT_F06.13481.13481.3 0.337 14/56 R.RPGSLPAPPPSQLPR.N "sp|P39880|CUX1_HUMAN,tr|A0A2R8Y852|A0A2R8Y852_HUMAN" 2 1568.8787 1.48 82771 13481 3 1568.881288 523.9668 Homeobox protein cut-like 1 OS=Homo sapiens OX=9606 GN=CUX1 PE=1 SV=3 12 2404.1 - 1.21E+06 - - - 1.6432 - 2.723 0.154 - 302.5 1 2 0 0.0026 15 0 0 0 3.45E+08 2.32E+08 - - - 2.8701 1 221125_WJC_METTL3_EV_vs_WT_F06.13485.13485.3 1.32E-05 13/48 R.KASGPPVSELITK.A "sp|P10412|H14_HUMAN,sp|P16403|H12_HUMAN,sp|P16402|H13_HUMAN" 3 1325.7555 0.72 82774 13485 3 1325.755455 442.9258 Histone H1.4 OS=Homo sapiens OX=9606 GN=H1-4 PE=1 SV=2 8.59 2404.4 - 1.33E+06 - - - -0.0091 - 2.574 0.523 - 243.3 1 2 0 0 13 0 0 0 7.40E+07 1.03E+08 - - - 6.9343 1 221125_WJC_METTL3_EV_vs_WT_F06.13486.13486.2 2.59E-07 14/22 K.TGNLGNVVHIER[166.11].F "sp|Q6P5R6|RL22L_HUMAN,tr|H0Y8C2|H0Y8C2_HUMAN,tr|C9JYQ9|C9JYQ9_HUMAN" 3 1317.7029 1.05 82775 13486 2 1317.70787 659.8587 60S ribosomal protein L22-like 1 OS=Homo sapiens OX=9606 GN=RPL22L1 PE=1 SV=2 6.41 2404.5 - 1.01E+06 - - - 3.796 - 2.74 0.586 - 698.9 1 2 0 0.005 12 0 0 0 3.38E+07 3.22E+07 - - - 6.0197 0.9999 221125_WJC_METTL3_EV_vs_WT_F06.13487.13487.3 1.42E-05 15/60 R.VGTVIGSNK[136.11]LEQMPSK[136.11].E "sp|P09874|PARP1_HUMAN,tr|A0A7I2V3E1|A0A7I2V3E1_HUMAN" 2 1702.9259 1.02 82776 13487 3 1702.925816 568.6492 Poly [ADP-ribose] polymerase 1 OS=Homo sapiens OX=9606 GN=PARP1 PE=1 SV=4 8.56 2404.6 - 885263 - - - -0.0235 - 3.115 0.445 - 273.6 1 2 1 0 16 0 0 0 1.36E+07 1.33E+07 - - - 6.4167 0.998 221125_WJC_METTL3_EV_vs_WT_F06.13488.13488.2 0.0785 14/24 K.DKFTDSAIAMNSK.V "sp|Q8WWM7|ATX2L_HUMAN,tr|H3BSK9|H3BSK9_HUMAN,tr|H3BUE3|H3BUE3_HUMAN,tr|H3BUF6|H3BUF6_HUMAN" 4 1426.6762 0.82 82777 13488 2 1426.674127 714.3454 Ataxin-2-like protein OS=Homo sapiens OX=9606 GN=ATXN2L PE=1 SV=2 5.96 2404.7 - 731592 - - - -1.4741 - 2.648 0.453 - 580.7 1 2 1 -0.0021 13 0 0 0 1.94E+07 2.36E+07 - - - 4.8855 0.9998 221125_WJC_METTL3_EV_vs_WT_F06.13489.13489.3 0.0071 17/60 R.VGTVIGSNKLEQMPSK.E "sp|P09874|PARP1_HUMAN,tr|A0A7I2V3E1|A0A7I2V3E1_HUMAN" 2 1686.8975 1.02 82778 13489 3 1686.900288 563.3064 Poly [ADP-ribose] polymerase 1 OS=Homo sapiens OX=9606 GN=PARP1 PE=1 SV=4 8.56 2404.9 - 725097 - - - 1.6788 - 3.047 0.454 - 471.6 1 2 1 0.0028 16 0 0 0 1.36E+07 1.33E+07 - - - 6.4596 1 221125_WJC_METTL3_EV_vs_WT_F06.13490.13490.2 2.02E-08 15/24 K.DK[136.11]FTDSAIAMNSK[136.11].V "sp|Q8WWM7|ATX2L_HUMAN,tr|H3BSK9|H3BSK9_HUMAN,tr|H3BUE3|H3BUE3_HUMAN,tr|H3BUF6|H3BUF6_HUMAN" 4 1442.7046 0.82 82779 13490 2 1442.703967 722.3596 Ataxin-2-like protein OS=Homo sapiens OX=9606 GN=ATXN2L PE=1 SV=2 5.96 2405 - 715245 - - - -0.4596 - 3.005 0.533 - 590.9 1 2 1 -0.0007 13 0 0 0 1.94E+07 2.36E+07 - - - 5.8014 1 221125_WJC_METTL3_EV_vs_WT_F06.13491.13491.3 1.37E-06 13/48 R.K[136.11]NPLPPSVGVVDK[136.11].K sp|Q8NC51|PAIRB_HUMAN 1 1364.7999 0.39 82780 13491 3 1364.801537 455.9406 Plasminogen activator inhibitor 1 RNA-binding protein OS=Homo sapiens OX=9606 GN=SERBP1 PE=1 SV=2 8.59 2405.1 - 480538 - - - 1.2353 - 2.756 0.437 - 196.3 1 2 0 0.0017 13 0 0 0 4.41E+06 1.14E+07 - - - 6.1603 0.9999 221125_WJC_METTL3_EV_vs_WT_F06.13492.13492.3 1.06E-05 13/56 K.C[160.03]EELSGLHGQLQEAR[166.11].A "sp|Q9P2E9|RRBP1_HUMAN,tr|A0A087WVV2|A0A087WVV2_HUMAN,tr|F8W7S5|F8W7S5_HUMAN" 3 1735.8187 1.31 82781 13492 3 1735.815627 579.6135 Ribosome-binding protein 1 OS=Homo sapiens OX=9606 GN=RRBP1 PE=1 SV=5 4.75 2405.3 - 380428 - - - -1.7715 - 2.527 0.477 - 211.9 1 2 0 -0.0031 15 0 0 0 5.19E+06 3.96E+06 - - - 6.2762 0.9999 221125_WJC_METTL3_EV_vs_WT_F06.13493.13493.2 2.13E-05 16/24 R.K[136.11]ASGPPVSELITK[136.11].A "sp|P10412|H14_HUMAN,sp|P16403|H12_HUMAN,sp|P16402|H13_HUMAN" 3 1341.7839 0.62 82782 13493 2 1341.784934 671.8992 Histone H1.4 OS=Homo sapiens OX=9606 GN=H1-4 PE=1 SV=2 8.59 2405.4 - 361973 - - - 0.7952 - 3.14 0.472 - 729.9 1 2 0 0.0011 13 0 0 0 1.12E+07 1.79E+07 - - - 5.4635 0.9858 221125_WJC_METTL3_EV_vs_WT_F06.13496.13496.3 0.287 Dec-32 K.EKIYVLLRR.Q sp|P84090|ERH_HUMAN 1 1188.7343 2.37 82785 13496 3 1188.733692 397.252 Enhancer of rudimentary homolog OS=Homo sapiens OX=9606 GN=ERH PE=1 SV=1 9.99 2405.8 - 284850 - - - -0.493 - 2.139 0.153 - 228.2 1 2 1 -0.0006 9 0 0 0 1.94E+07 8.20E+06 - - - 2.5371 1 221125_WJC_METTL3_EV_vs_WT_F06.13499.13499.3 2.24E-06 15/44 K.TGNLGNVVHIER.F "sp|Q6P5R6|RL22L_HUMAN,tr|H0Y8C2|H0Y8C2_HUMAN,tr|C9JYQ9|C9JYQ9_HUMAN" 3 1307.6946 1.21 82786 13499 3 1307.696331 436.9055 60S ribosomal protein L22-like 1 OS=Homo sapiens OX=9606 GN=RPL22L1 PE=1 SV=2 6.41 2406.2 - 2.48E+07 - - - 1.3252 - 3.202 0.519 - 527.3 1 2 0 0.0017 12 0 0 0 4.06E+08 3.35E+08 - - - 7.5517 0.9999 221125_WJC_METTL3_EV_vs_WT_F06.13501.13501.3 0.00409 Dec-44 K.DGTHVLQGLSSR.T sp|Q5VVQ6|OTU1_HUMAN 1 1268.6473 2.38 82788 13501 3 1268.645388 423.8897 Ubiquitin thioesterase OTU1 OS=Homo sapiens OX=9606 GN=YOD1 PE=1 SV=1 6.74 2406.4 - 1.28E+06 - - - -1.5174 - 2.584 0.388 - 164.8 1 2 0 -0.0019 12 0 0 0 3.83E+07 1.60E+07 - - - 5.4967 0.9984 221125_WJC_METTL3_EV_vs_WT_F06.13502.13502.2 0.00166 14/22 K.KPSISITTESLK.S "sp|Q9UKV3|ACINU_HUMAN,tr|G3V3B0|G3V3B0_HUMAN,tr|S4R3H4|S4R3H4_HUMAN,tr|E7EQT4|E7EQT4_HUMAN,tr|G3V3T3|G3V3T3_HUMAN" 5 1302.7395 1.28 82789 13502 2 1302.745608 652.377 Apoptotic chromatin condensation inducer in the nucleus OS=Homo sapiens OX=9606 GN=ACIN1 PE=1 SV=2 8.59 2406.5 - 562782 - - - 4.7024 - 2.771 0.483 - 501.9 1 2 0 0.0061 12 0 0 0 1.92E+07 1.50E+07 - - - 5.2882 1 221125_WJC_METTL3_EV_vs_WT_F06.13507.13507.3 0.000385 14/48 K.AFTQLSNLQSHQR.Q sp|Q5T0B9|ZN362_HUMAN 1 1528.7746 1.57 82792 13507 3 1528.775197 510.5988 Zinc finger protein 362 OS=Homo sapiens OX=9606 GN=ZNF362 PE=1 SV=1 9.8 2407.1 - 1.19E+06 - - - 0.365 - 2.751 0.44 - 237.1 1 2 0 0.0006 13 0 0 0 3.27E+07 2.09E+07 - - - 6.1891 1 221125_WJC_METTL3_EV_vs_WT_F06.13508.13508.3 5.53E-06 Nov-44 R.YDGVHFSVNDSK.Y "sp|O15047|SET1A_HUMAN,tr|A0A804HLA6|A0A804HLA6_HUMAN,tr|C9J2Z9|C9J2Z9_HUMAN" 3 1366.6153 1.42 82793 13508 3 1366.61699 456.5457 Histone-lysine N-methyltransferase SETD1A OS=Homo sapiens OX=9606 GN=SETD1A PE=1 SV=3 5.21 2407.2 - 822955 - - - 1.2044 - 2.201 0.501 - 90.1 1 2 0 0.0016 12 0 0 0 2.89E+07 2.04E+07 - - - 6.3119 0.9997 221125_WJC_METTL3_EV_vs_WT_F06.13509.13509.3 0.000104 Dec-48 R.K[136.11]NDPLPISTVGTR[166.11].G "sp|Q9NVM9|INT13_HUMAN,tr|H0YH12|H0YH12_HUMAN" 2 1414.7899 0.67 82794 13509 3 1414.793726 472.6039 Integrator complex subunit 13 OS=Homo sapiens OX=9606 GN=INTS13 PE=1 SV=2 8.75 2407.3 - 599584 - - - 2.7057 - 2.5 0.381 - 266.3 1 2 0 0.0038 13 0 0 0 5.10E+06 7.65E+06 - - - 5.271 1 221125_WJC_METTL3_EV_vs_WT_F06.13514.13514.3 1.39E-07 15/48 R.YNIPHGPVVGSTR[166.11].R "sp|P50402|EMD_HUMAN,tr|A0A804HLA2|A0A804HLA2_HUMAN,tr|A0A804HIV7|A0A804HIV7_HUMAN" 3 1405.7342 2.73 82797 13514 3 1405.737664 469.5853 Emerin OS=Homo sapiens OX=9606 GN=EMD PE=1 SV=1 8.75 2407.9 - 1.76E+06 - - - 2.487 - 2.832 0.543 - 218.2 1 2 0 0.0035 13 0 0 0 1.03E+08 3.77E+07 - - - 7.4154 1 221125_WJC_METTL3_EV_vs_WT_F06.13517.13517.3 0.00047 14/44 K.YNIWC[160.03]STEHGNK.R sp|Q9Y5A9|YTHD2_HUMAN 1 1507.6514 1.32 82800 13517 3 1507.654447 503.5577 YTH domain-containing family protein 2 OS=Homo sapiens OX=9606 GN=YTHDF2 PE=1 SV=2 6.74 2408.2 - 870264 - - - 2.0131 - 2.154 0.568 - 175.1 1 2 0 0.003 12 0 0 0 2.67E+08 2.03E+08 - - - 6.9987 0.9903 221125_WJC_METTL3_EV_vs_WT_F06.13521.13521.2 0.45 14/26 D.R[166.11]FSGSGSGTDFTLK.L "sp|A2NJV5|KV229_HUMAN,sp|A0A087WW87|KV240_HUMAN,sp|P06310|KV230_HUMAN,sp|A0A075B6S2|KVD29_HUMAN,sp|P01614|KVD40_HUMAN,sp|P01615|KVD28_HUMAN,sp|A0A075B6S6|KVD30_HUMAN,sp|A0A075B6P5|KV228_HUMAN,sp|A0A0A0MRZ7|KVD26_HUMAN" 9 1468.7186 - 82804 13521 2 1468.718978 735.3666 Immunoglobulin kappa variable 2-29 OS=Homo sapiens OX=9606 GN=IGKV2-29 PE=3 SV=2 8.75 2408.7 - 294677 - - - 0.273 - 2.43 0.426 - 385.6 1 1 0 0.0004 14 0 0 0 - - - - - 4.4154 0.9986 221125_WJC_METTL3_EV_vs_WT_F06.13527.13527.3 2.62E-05 17/52 D.RFSGSGSGTDFTLK.L "sp|A2NJV5|KV229_HUMAN,sp|A0A087WW87|KV240_HUMAN,sp|P06310|KV230_HUMAN,sp|A0A075B6S2|KVD29_HUMAN,sp|P01614|KVD40_HUMAN,sp|P01615|KVD28_HUMAN,sp|A0A075B6S6|KVD30_HUMAN,sp|A0A075B6P5|KV228_HUMAN,sp|A0A0A0MRZ7|KVD26_HUMAN" 9 1458.7103 57.1 82808 13527 3 1458.711524 487.244 Immunoglobulin kappa variable 2-29 OS=Homo sapiens OX=9606 GN=IGKV2-29 PE=3 SV=2 8.75 2409.4 - 2.90E+06 - - - 0.8343 - 3.076 0.557 - 438.7 1 1 0 0.0012 14 0 0 0 9.87E+07 1.73E+06 - - - 7.7357 0.9998 221125_WJC_METTL3_EV_vs_WT_F06.13528.13528.2 0.005 16/24 R.KASGPPVSELITK.A "sp|P10412|H14_HUMAN,sp|P16403|H12_HUMAN,sp|P16402|H13_HUMAN" 3 1325.7555 0.6 82809 13528 2 1325.753124 663.885 Histone H1.4 OS=Homo sapiens OX=9606 GN=H1-4 PE=1 SV=2 8.59 2409.6 - 566040 - - - -1.7673 - 2.704 0.449 - 676.6 1 2 0 -0.0023 13 0 0 0 9.40E+06 1.56E+07 - - - 4.9096 0.9694 221125_WJC_METTL3_EV_vs_WT_F06.13529.13529.4 0.00864 Nov-72 R.FPPYHVGQTFDR[166.11]R[166.11].S sp|P16989|YBOX3_HUMAN 1 1638.817 0.91 82810 13529 4 1638.820645 410.7115 Y-box-binding protein 3 OS=Homo sapiens OX=9606 GN=YBX3 PE=1 SV=4 8.75 2409.7 - 416562 - - - 2.2242 - 2.037 0.198 - 87 2 2 0 0.0036 13 0 0 0 7.18E+06 7.90E+06 - - - 0.9827 0.9836 221125_WJC_METTL3_EV_vs_WT_F06.13533.13533.2 0.00581 26-Oct D.RFSGSGSGTDFTLK.L "sp|A2NJV5|KV229_HUMAN,sp|A0A087WW87|KV240_HUMAN,sp|P06310|KV230_HUMAN,sp|A0A075B6S2|KVD29_HUMAN,sp|P01614|KVD40_HUMAN,sp|P01615|KVD28_HUMAN,sp|A0A075B6S6|KVD30_HUMAN,sp|A0A075B6P5|KV228_HUMAN,sp|A0A0A0MRZ7|KVD26_HUMAN" 9 1458.7103 999 82812 13533 2 1458.710707 730.3624 Immunoglobulin kappa variable 2-29 OS=Homo sapiens OX=9606 GN=IGKV2-29 PE=3 SV=2 8.75 2410.1 - 670534 - - - 0.2742 - 2.189 0.365 - 152.8 1 1 0 0.0004 14 0 0 0 1.90E+07 0.00E+00 - - - 3.7028 1 221125_WJC_METTL3_EV_vs_WT_F06.13537.13537.2 1.11E-07 30-Sep A.FYGQTLGQAQAHSQEQ.- sp|Q96I24|FUBP3_HUMAN 1 1791.8176 - 82816 13537 2 1791.818914 896.9161 Far upstream element-binding protein 3 OS=Homo sapiens OX=9606 GN=FUBP3 PE=1 SV=2 5.24 2410.6 - 408674 - - - 0.7188 - 2.312 0.632 - 174 1 1 0 0.0013 16 0 0 0 - - - - - 5.7691 0.9995 221125_WJC_METTL3_EV_vs_WT_F06.13541.13541.2 0.000221 22-Dec K.YNIWC[160.03]STEHGNK[136.11].R sp|Q9Y5A9|YTHD2_HUMAN 1 1515.6656 1.43 82820 13541 2 1515.669799 758.8401 YTH domain-containing family protein 2 OS=Homo sapiens OX=9606 GN=YTHDF2 PE=1 SV=2 6.74 2411.1 - 206499 - - - 2.7625 - 1.884 0.567 - 418.7 1 2 0 0.0042 12 0 0 0 2.31E+07 1.62E+07 - - - 4.8941 0.9999 221125_WJC_METTL3_EV_vs_WT_F06.13545.13545.3 0.00047 Dec-48 R.SIFQHIQSAQSQR[166.11].S "sp|Q9Y2W1|TR150_HUMAN,tr|A0A3B3ITZ9|A0A3B3ITZ9_HUMAN" 2 1538.7829 2.7 82823 13545 3 1538.785375 513.9349 Thyroid hormone receptor-associated protein 3 OS=Homo sapiens OX=9606 GN=THRAP3 PE=1 SV=2 9.49 2411.4 - 1.88E+06 - - - 1.6026 - 2.342 0.437 - 143.2 1 2 0 0.0025 13 0 0 0 5.66E+09 2.10E+09 - - - 5.7188 1 221125_WJC_METTL3_EV_vs_WT_F06.13547.13547.3 1.37E-05 Nov-52 R.WLHEINQNC[160.03]DDVC[160.03]R[166.11].L "sp|Q15286|RAB35_HUMAN,tr|F5H157|F5H157_HUMAN" 2 1867.7969 0.95 82825 13547 3 1867.796164 623.6063 Ras-related protein Rab-35 OS=Homo sapiens OX=9606 GN=RAB35 PE=1 SV=1 4.54 2411.6 - 628039 - - - -0.4053 - 2.344 0.512 - 127.3 1 2 0 -0.0008 14 0 0 0 5.76E+06 6.08E+06 - - - 6.5119 0.9823 221125_WJC_METTL3_EV_vs_WT_F06.13550.13550.3 0.0721 Jul-36 K.RLHVSNIPFR.F "sp|O43251|RFOX2_HUMAN,sp|Q9NWB1|RFOX1_HUMAN,sp|A6NFN3|RFOX3_HUMAN,tr|A0A6Q8PGE0|A0A6Q8PGE0_HUMAN,tr|A0A6Q8PH77|A0A6Q8PH77_HUMAN,tr|A0A286YEU2|A0A286YEU2_HUMAN,tr|A0A087X2B1|A0A087X2B1_HUMAN,tr|F8VR27|F8VR27_HUMAN,tr|B7Z1U7|B7Z1U7_HUMAN,tr|B0QYY6|B0QYY6_HUMAN,tr|B0QYV1|B0QYV1_HUMAN,tr|A0A6Q8PHA3|A0A6Q8PHA3_HUMAN,tr|A0A3B3ITL7|A0A3B3ITL7_HUMAN,tr|F8VZY7|F8VZY7_HUMAN,tr|B0QYY4|B0QYY4_HUMAN,tr|J3KNW3|J3KNW3_HUMAN,tr|F8VZG9|F8VZG9_HUMAN,tr|J3QRF4|J3QRF4_HUMAN,tr|F8VRS4|F8VRS4_HUMAN,tr|A0A6Q8PFM4|A0A6Q8PFM4_HUMAN,tr|S4R469|S4R469_HUMAN,tr|A0A804HKG7|A0A804HKG7_HUMAN,tr|A0A0G2JRA5|A0A0G2JRA5_HUMAN,tr|A0A804HJM2|A0A804HJM2_HUMAN,tr|J3QQZ2|J3QQZ2_HUMAN,tr|I3L1D4|I3L1D4_HUMAN,tr|B0QYY7|B0QYY7_HUMAN,tr|A0A0G2JSB3|A0A0G2JSB3_HUMAN" 28 1237.7044 1.13 82828 13550 3 1237.704176 413.5754 RNA binding protein fox-1 homolog 2 OS=Homo sapiens OX=9606 GN=RBFOX2 PE=1 SV=3 12 2412 - 187801 - - - -0.16 - 1.601 0.174 - 44.1 7 2 0 -0.0002 10 0 0 0 2.01E+06 1.77E+06 - - - 1.4632 1 221125_WJC_METTL3_EV_vs_WT_F06.13553.13553.2 1.12E-09 16/24 R.SIFQHIQSAQSQR.S "sp|Q9Y2W1|TR150_HUMAN,tr|A0A3B3ITZ9|A0A3B3ITZ9_HUMAN" 2 1528.7746 2.5 82829 13553 2 1528.773859 765.3946 Thyroid hormone receptor-associated protein 3 OS=Homo sapiens OX=9606 GN=THRAP3 PE=1 SV=2 9.49 2412.4 - 1.05E+06 - - - -0.5102 - 3.036 0.623 - 1108.9 1 2 0 -0.0008 13 0 0 0 9.11E+08 3.64E+08 - - - 6.4925 0.9993 221125_WJC_METTL3_EV_vs_WT_F06.13556.13556.2 5.31E-05 13/22 K.YNIWC[160.03]STEHGNK.R sp|Q9Y5A9|YTHD2_HUMAN 1 1507.6514 1.43 82832 13556 2 1507.657001 754.833 YTH domain-containing family protein 2 OS=Homo sapiens OX=9606 GN=YTHDF2 PE=1 SV=2 6.74 2412.8 - 814684 - - - 3.7071 - 1.967 0.606 - 451.5 1 2 0 0.0056 12 0 0 0 2.31E+07 1.62E+07 - - - 5.2952 1 221125_WJC_METTL3_EV_vs_WT_F06.13557.13557.2 5.93E-10 17/20 K.HNMNIGTWDEK[136.11].G "sp|Q7Z739|YTHD3_HUMAN,tr|A0A087X0Q1|A0A087X0Q1_HUMAN,tr|A0A024R7W5|A0A024R7W5_HUMAN,tr|A0A087WY31|A0A087WY31_HUMAN" 4 1351.607 1.29 82833 13557 2 1351.607766 676.8108 YTH domain-containing family protein 3 OS=Homo sapiens OX=9606 GN=YTHDF3 PE=1 SV=1 5.32 2412.9 - 810581 - - - 0.5408 - 3.505 0.697 - 746.9 1 2 0 0.0007 11 0 0 0 2.72E+07 2.11E+07 - - - 7.5817 0.9998 221125_WJC_METTL3_EV_vs_WT_F06.13558.13558.2 2.19E-05 17/22 K.K[136.11]PSISITTESLK[136.11].S "sp|Q9UKV3|ACINU_HUMAN,tr|G3V3B0|G3V3B0_HUMAN,tr|S4R3H4|S4R3H4_HUMAN,tr|E7EQT4|E7EQT4_HUMAN,tr|G3V3T3|G3V3T3_HUMAN" 5 1318.7679 1.44 82834 13558 2 1318.769725 660.3912 Apoptotic chromatin condensation inducer in the nucleus OS=Homo sapiens OX=9606 GN=ACIN1 PE=1 SV=2 8.59 2413 - 654265 - - - 1.3975 - 2.899 0.481 - 931.8 1 2 0 0.0018 12 0 0 0 2.76E+07 1.92E+07 - - - 5.3936 1 221125_WJC_METTL3_EV_vs_WT_F06.13560.13560.2 5.48E-05 17/24 R.SIFQHIQSAQSQR[166.11].S "sp|Q9Y2W1|TR150_HUMAN,tr|A0A3B3ITZ9|A0A3B3ITZ9_HUMAN" 2 1538.7829 2.5 82836 13560 2 1538.784517 770.3987 Thyroid hormone receptor-associated protein 3 OS=Homo sapiens OX=9606 GN=THRAP3 PE=1 SV=2 9.49 2413.2 - 464121 - - - 1.045 - 3.204 0.565 - 1261.5 1 2 0 0.0016 13 0 0 0 9.10E+08 3.64E+08 - - - 6.2021 1 221125_WJC_METTL3_EV_vs_WT_F06.13561.13561.2 1.97E-07 15/32 R.TPAPEPEPC[160.03]EASELPAK.R "sp|Q9ULV3|CIZ1_HUMAN,tr|Q5SYW2|Q5SYW2_HUMAN,tr|F5H2X7|F5H2X7_HUMAN,tr|H0Y5D5|H0Y5D5_HUMAN,tr|A0A494C0L7|A0A494C0L7_HUMAN,tr|Q9BTG3|Q9BTG3_HUMAN" 6 1821.8455 4.87 82837 13561 2 1821.844575 911.93 Cip1-interacting zinc finger protein OS=Homo sapiens OX=9606 GN=CIZ1 PE=1 SV=2 4.09 2413.3 - 328469 - - - -0.4973 - 2.84 0.633 - 532.5 1 2 0 -0.0009 17 0 0 0 4.21E+07 8.63E+06 - - - 6.2823 0.9778 221125_WJC_METTL3_EV_vs_WT_F06.13563.13563.2 1.99E-06 30-Nov K.QNVPSGGPVPSPQTYR.P "sp|Q5JSZ5|PRC2B_HUMAN,tr|A0A804HKU3|A0A804HKU3_HUMAN,tr|A0A804HJR4|A0A804HJR4_HUMAN" 3 1682.8376 0.65 82839 13563 2 1682.833535 842.4261 Protein PRRC2B OS=Homo sapiens OX=9606 GN=PRRC2B PE=1 SV=2 8.75 2413.6 - 247583 - - - -2.4352 - 2.043 0.536 - 267 1 1 0 -0.0041 16 0 0 0 1.46E+06 2.24E+06 - - - 4.755 0.9999 221125_WJC_METTL3_EV_vs_WT_F06.13566.13566.3 0.000173 Dec-44 K.TGNLGNVVHIER[166.11].F "sp|Q6P5R6|RL22L_HUMAN,tr|H0Y8C2|H0Y8C2_HUMAN,tr|C9JYQ9|C9JYQ9_HUMAN" 3 1317.7029 1.21 82841 13566 3 1317.70506 440.2416 60S ribosomal protein L22-like 1 OS=Homo sapiens OX=9606 GN=RPL22L1 PE=1 SV=2 6.41 2413.9 - 3.23E+06 - - - 1.6635 - 2.055 0.456 - 232.5 1 2 0 0.0022 12 0 0 0 4.06E+08 3.35E+08 - - - 5.6198 0.996 221125_WJC_METTL3_EV_vs_WT_F06.13569.13569.3 1.2 Aug-44 K.K[136.11]PSISITTESLK[136.11].S "sp|Q9UKV3|ACINU_HUMAN,tr|G3V3B0|G3V3B0_HUMAN,tr|S4R3H4|S4R3H4_HUMAN,tr|E7EQT4|E7EQT4_HUMAN,tr|G3V3T3|G3V3T3_HUMAN" 5 1318.7679 1.25 82844 13569 3 1318.769203 440.5966 Apoptotic chromatin condensation inducer in the nucleus OS=Homo sapiens OX=9606 GN=ACIN1 PE=1 SV=2 8.59 2414.1 - 3.23E+06 - - - 1.0017 - 1.751 0.21 - 112.4 1 2 0 0.0013 12 0 0 0 7.06E+07 5.65E+07 - - - 2.4337 1 221125_WJC_METTL3_EV_vs_WT_F06.13571.13571.3 9.72E-06 Dec-52 R.WLHEINQNC[160.03]DDVC[160.03]R.L "sp|Q15286|RAB35_HUMAN,tr|F5H157|F5H157_HUMAN" 2 1857.7887 0.95 82846 13571 3 1857.791011 620.2702 Ras-related protein Rab-35 OS=Homo sapiens OX=9606 GN=RAB35 PE=1 SV=1 4.54 2414.3 - 1.15E+06 - - - 1.2703 - 2.286 0.563 - 294.5 1 2 0 0.0024 14 0 0 0 5.76E+06 6.08E+06 - - - 7.0135 1 221125_WJC_METTL3_EV_vs_WT_F06.13572.13572.3 8.93E-05 18/64 K.AEVVETTQVYTEEETR[166.11]R[166.11].A "sp|Q15149|PLEC_HUMAN,tr|H0YDN1|H0YDN1_HUMAN" 2 2058.9973 1.59 82847 13572 3 2058.996199 687.3397 Plectin OS=Homo sapiens OX=9606 GN=PLEC PE=1 SV=3 4.33 2414.4 - 1.12E+06 - - - -0.5192 - 2.713 0.502 - 396.1 1 2 0 -0.0011 17 0 0 0 1.91E+07 1.20E+07 - - - 6.6579 0.9998 221125_WJC_METTL3_EV_vs_WT_F06.13582.13582.2 0.00304 22-Nov R.ALEESNYELEGK.L "sp|P13645|K1C10_HUMAN,tr|A0A1B0GVI3|A0A1B0GVI3_HUMAN" 2 1380.6409 46.54 82856 13582 2 1380.64229 691.3277 "Keratin, type I cytoskeletal 10 OS=Homo sapiens OX=9606 GN=KRT10 PE=1 SV=6" 4.09 2415.4 - 4.77E+06 - - - 1.014 - 2.218 0.431 - 359.6 1 2 0 0.0014 12 0 0 0 4.47E+07 9.61E+05 - - - 4.3199 1 221125_WJC_METTL3_EV_vs_WT_F06.13583.13583.3 2.48E-05 14/44 K.KPSISITTESLK.S "sp|Q9UKV3|ACINU_HUMAN,tr|G3V3B0|G3V3B0_HUMAN,tr|S4R3H4|S4R3H4_HUMAN,tr|E7EQT4|E7EQT4_HUMAN,tr|G3V3T3|G3V3T3_HUMAN" 5 1302.7395 1.26 82857 13583 3 1302.739499 435.2538 Apoptotic chromatin condensation inducer in the nucleus OS=Homo sapiens OX=9606 GN=ACIN1 PE=1 SV=2 8.59 2415.4 - 3.60E+06 - - - 0.013 - 2.792 0.471 - 451.2 1 2 0 0 12 0 0 0 7.10E+07 5.65E+07 - - - 6.6372 0.987 221125_WJC_METTL3_EV_vs_WT_F06.13584.13584.2 1.80E-07 16/20 L.FQHIQSAQSQR.S "sp|Q9Y2W1|TR150_HUMAN,tr|A0A3B3ITZ9|A0A3B3ITZ9_HUMAN" 2 1328.6585 2.6 82858 13584 2 1328.659167 665.3365 Thyroid hormone receptor-associated protein 3 OS=Homo sapiens OX=9606 GN=THRAP3 PE=1 SV=2 9.76 2415.5 - 3.32E+06 - - - 0.4674 - 2.137 0.401 - 1075.5 1 1 0 0.0006 11 0 0 0 1.87E+08 7.19E+07 - - - 4.057 1 221125_WJC_METTL3_EV_vs_WT_F06.13586.13586.3 3.77E-05 Oct-40 K.HNMNIGTWDEK[136.11].G "sp|Q7Z739|YTHD3_HUMAN,tr|A0A087X0Q1|A0A087X0Q1_HUMAN,tr|A0A024R7W5|A0A024R7W5_HUMAN,tr|A0A087WY31|A0A087WY31_HUMAN" 4 1351.607 1.22 82860 13586 3 1351.607259 451.543 YTH domain-containing family protein 3 OS=Homo sapiens OX=9606 GN=YTHDF3 PE=1 SV=1 5.32 2415.6 - 2.96E+06 - - - 0.1657 - 2.284 0.498 - 200.7 1 2 0 0.0002 11 0 0 0 3.14E+07 2.56E+07 - - - 6.4385 1 221125_WJC_METTL3_EV_vs_WT_F06.13587.13587.2 7.17E-10 13/20 K.HNMNIGTWDEK.G "sp|Q7Z739|YTHD3_HUMAN,tr|A0A087X0Q1|A0A087X0Q1_HUMAN,tr|A0A024R7W5|A0A024R7W5_HUMAN,tr|A0A087WY31|A0A087WY31_HUMAN" 4 1343.5928 1.29 82861 13587 2 1343.592906 672.8037 YTH domain-containing family protein 3 OS=Homo sapiens OX=9606 GN=YTHDF3 PE=1 SV=1 5.32 2415.7 - 2.84E+06 - - - 0.0528 - 2.708 0.659 - 411.3 1 2 0 0.0001 11 0 0 0 2.72E+07 2.11E+07 - - - 6.6033 0.999 221125_WJC_METTL3_EV_vs_WT_F06.13589.13589.3 0.00135 Nov-48 R.DRDGSFPSEPGLR.R sp|Q00587|BORG5_HUMAN 1 1431.6743 1.34 82863 13589 3 1431.67101 478.232 Cdc42 effector protein 1 OS=Homo sapiens OX=9606 GN=CDC42EP1 PE=1 SV=1 4.56 2415.8 - 1.62E+06 - - - -2.2673 - 2.006 0.424 - 139.8 1 2 1 -0.0032 13 0 0 0 1.93E+07 1.45E+07 - - - 5.1537 1 221125_WJC_METTL3_EV_vs_WT_F06.13590.13590.3 2.96E-08 19/64 K.DVGRPNFEEGGPTSVGR.K "sp|Q6Y7W6|GGYF2_HUMAN,tr|E7ESB6|E7ESB6_HUMAN" 2 1772.8442 0.93 82864 13590 3 1772.845279 591.9553 GRB10-interacting GYF protein 2 OS=Homo sapiens OX=9606 GN=GIGYF2 PE=1 SV=1 4.68 2415.9 - 1.32E+06 - - - 0.6227 - 3.01 0.582 - 315.5 1 2 0 0.0011 17 0 0 0 1.17E+07 1.26E+07 - - - 7.8123 1 221125_WJC_METTL3_EV_vs_WT_F06.13595.13595.2 4.21E-11 16/24 K.C[160.03]LDENLEDASQC[160.03]K[136.11].K sp|Q5JTJ3|COA6_HUMAN 1 1588.6589 0.79 82869 13595 2 1588.656611 795.3367 Cytochrome c oxidase assembly factor 6 homolog OS=Homo sapiens OX=9606 GN=COA6 PE=1 SV=1 3.92 2416.5 - 619410 - - - -1.4232 - 3.084 0.653 - 753 1 2 0 -0.0023 13 0 0 0 2.85E+06 3.59E+06 - - - 6.7538 0.9999 221125_WJC_METTL3_EV_vs_WT_F06.13597.13597.3 4.72E-06 20/60 K.VIAQQVQLQQQQEQVR.L sp|Q01664|TFAP4_HUMAN 1 1922.0334 1.9 82871 13597 3 1922.040924 641.6851 Transcription factor AP-4 OS=Homo sapiens OX=9606 GN=TFAP4 PE=1 SV=2 5.97 2416.8 - 602954 - - - 3.9287 - 3.725 0.544 - 756.4 1 2 0 0.0076 16 0 0 0 4.39E+07 2.31E+07 - - - 7.9773 0.9347 221125_WJC_METTL3_EV_vs_WT_F06.13598.13598.3 0.000337 13/60 K.QNVPSGGPVPSPQTYR.P "sp|Q5JSZ5|PRC2B_HUMAN,tr|A0A804HKU3|A0A804HKU3_HUMAN,tr|A0A804HJR4|A0A804HJR4_HUMAN" 3 1682.8376 3.4 82872 13598 3 1682.835225 561.9532 Protein PRRC2B OS=Homo sapiens OX=9606 GN=PRRC2B PE=1 SV=2 8.75 2416.9 - 510477 - - - -1.4309 - 2.381 0.27 - 176.4 1 1 0 -0.0024 16 0 0 0 7.04E+07 2.07E+07 - - - 3.7755 0.9924 221125_WJC_METTL3_EV_vs_WT_F06.13603.13603.2 0.0049 14/20 L.FQHIQSAQSQR[166.11].S "sp|Q9Y2W1|TR150_HUMAN,tr|A0A3B3ITZ9|A0A3B3ITZ9_HUMAN" 2 1338.6668 2.6 82875 13603 2 1338.665808 670.3407 Thyroid hormone receptor-associated protein 3 OS=Homo sapiens OX=9606 GN=THRAP3 PE=1 SV=2 9.76 2417.4 - 3.70E+06 - - - -0.753 - 2.204 0.506 - 840.1 1 1 0 -0.001 11 0 0 0 1.87E+08 7.19E+07 - - - 4.9159 1 221125_WJC_METTL3_EV_vs_WT_F06.13605.13605.3 5.14E-05 19/60 K.VIAQQVQLQQQQEQVR[166.11].L sp|Q01664|TFAP4_HUMAN 1 1932.0416 1.9 82877 13605 3 1932.040685 645.0212 Transcription factor AP-4 OS=Homo sapiens OX=9606 GN=TFAP4 PE=1 SV=2 5.97 2417.6 - 1.94E+06 - - - -0.4958 - 3.375 0.417 - 697.4 1 2 0 -0.001 16 0 0 0 4.39E+07 2.31E+07 - - - 6.31 0.9999 221125_WJC_METTL3_EV_vs_WT_F06.13608.13608.3 0.00291 13/56 R.TPVIDADKPVSSQLR.V "sp|Q14204|DYHC1_HUMAN,tr|A0A7P0T8N2|A0A7P0T8N2_HUMAN,tr|A0A7P0T9C4|A0A7P0T9C4_HUMAN,tr|A0A7P0TBJ7|A0A7P0TBJ7_HUMAN,tr|A0A804HHY6|A0A804HHY6_HUMAN,tr|A0A7P0T9K2|A0A7P0T9K2_HUMAN,tr|A0A7P0TB64|A0A7P0TB64_HUMAN,tr|A0A2R8Y706|A0A2R8Y706_HUMAN,tr|A0A7P0T916|A0A7P0T916_HUMAN,tr|A0A7P0TB75|A0A7P0TB75_HUMAN,tr|A0A7P0T8W5|A0A7P0T8W5_HUMAN,tr|A0A7P0T9S3|A0A7P0T9S3_HUMAN,tr|A0A7P0TAF3|A0A7P0TAF3_HUMAN,tr|A0A7P0T9F1|A0A7P0T9F1_HUMAN,tr|A0A7P0TAW9|A0A7P0TAW9_HUMAN,tr|A0A2R8YGC7|A0A2R8YGC7_HUMAN,tr|A0A7P0TA13|A0A7P0TA13_HUMAN,tr|A0A7P0T934|A0A7P0T934_HUMAN,tr|A0A7P0TAV5|A0A7P0TAV5_HUMAN,tr|A0A7P0T9Y3|A0A7P0T9Y3_HUMAN,tr|A0A7P0T7V5|A0A7P0T7V5_HUMAN,tr|A0A7P0T9R4|A0A7P0T9R4_HUMAN,tr|A0A2R8Y5T0|A0A2R8Y5T0_HUMAN,tr|A0A7P0T990|A0A7P0T990_HUMAN,tr|A0A7P0T942|A0A7P0T942_HUMAN,tr|A0A7P0TAS7|A0A7P0TAS7_HUMAN,tr|A0A2R8YFZ7|A0A2R8YFZ7_HUMAN,tr|A0A7P0T825|A0A7P0T825_HUMAN,tr|A0A2R8Y6H2|A0A2R8Y6H2_HUMAN,tr|A0A7P0TBC9|A0A7P0TBC9_HUMAN,tr|A0A7P0TAM4|A0A7P0TAM4_HUMAN" 31 1624.8784 1.06 82880 13608 3 1624.876322 542.6334 Cytoplasmic dynein 1 heavy chain 1 OS=Homo sapiens OX=9606 GN=DYNC1H1 PE=1 SV=5 5.63 2417.9 - 1.45E+06 - - - -1.3004 - 2.171 0.433 - 182 1 2 0 -0.0021 15 0 0 0 6.35E+06 5.98E+06 - - - 5.3897 0.9963 221125_WJC_METTL3_EV_vs_WT_F06.13610.13610.3 0.0192 18/60 R.VLDGPEKVPVVHVDEK.G sp|Q8TEM1|PO210_HUMAN 1 1758.9516 1.55 82882 13610 3 1758.952351 587.3245 Nuclear pore membrane glycoprotein 210 OS=Homo sapiens OX=9606 GN=NUP210 PE=1 SV=3 4.75 2418.1 - 1.02E+06 - - - 0.427 - 2.223 0.258 - 258.4 1 2 1 0.0008 16 0 0 0 1.14E+07 7.34E+06 - - - 3.466 0.9997 221125_WJC_METTL3_EV_vs_WT_F06.13611.13611.3 0.00177 Nov-48 R.VAIHYINPPNPAK[136.11].D "sp|P78406|RAE1L_HUMAN,tr|E9PQ57|E9PQ57_HUMAN" 2 1440.7969 1.92 82883 13611 3 1440.795016 481.2729 mRNA export factor OS=Homo sapiens OX=9606 GN=RAE1 PE=1 SV=1 8.57 2418.2 - 888629 - - - -1.2965 - 2.152 0.332 - 137 1 2 0 -0.0019 13 0 0 0 6.78E+07 3.54E+07 - - - 4.3189 0.9678 221125_WJC_METTL3_EV_vs_WT_F06.13613.13613.3 0.00347 Dec-44 K.LK[136.11]QSLPPGLAVK[136.11].E sp|P63173|RL38_HUMAN 1 1265.8042 1.35 82885 13613 3 1265.804371 422.942 60S ribosomal protein L38 OS=Homo sapiens OX=9606 GN=RPL38 PE=1 SV=2 10 2418.4 - 532447 - - - 0.1288 - 1.904 0.151 - 184.5 1 2 1 0.0002 12 0 0 0 8.07E+06 5.97E+06 - - - 2.0084 0.9987 221125_WJC_METTL3_EV_vs_WT_F06.13615.13615.3 1.03E-07 13/52 D.R[166.11]FSGSGSGTDFTLK.L "sp|A2NJV5|KV229_HUMAN,sp|A0A087WW87|KV240_HUMAN,sp|P06310|KV230_HUMAN,sp|A0A075B6S2|KVD29_HUMAN,sp|P01614|KVD40_HUMAN,sp|P01615|KVD28_HUMAN,sp|A0A075B6S6|KVD30_HUMAN,sp|A0A075B6P5|KV228_HUMAN,sp|A0A0A0MRZ7|KVD26_HUMAN" 9 1468.7186 - 82886 13615 3 1468.717486 490.5801 Immunoglobulin kappa variable 2-29 OS=Homo sapiens OX=9606 GN=IGKV2-29 PE=3 SV=2 8.75 2418.6 - 4.17E+06 - - - -0.7428 - 3.023 0.574 - 363.3 1 1 0 -0.0011 14 0 0 0 - - - - - 7.8791 0.8062 221125_WJC_METTL3_EV_vs_WT_F06.13616.13616.2 0.00452 Nov-34 T.AEPLAGDR[166.11]PPTGGHSSGR[166.11].S "sp|O00555|CAC1A_HUMAN,tr|A0A1C7CYY9|A0A1C7CYY9_HUMAN,tr|A0A1B0GU81|A0A1B0GU81_HUMAN,tr|A0A1B0GTW2|A0A1B0GTW2_HUMAN,tr|K7EKF7|K7EKF7_HUMAN,tr|A0A1B0GTN7|A0A1B0GTN7_HUMAN,tr|A0A087WW63|A0A087WW63_HUMAN,tr|K7EQ95|K7EQ95_HUMAN,tr|A0A1B0GUS3|A0A1B0GUS3_HUMAN" 9 1780.8719 0.001 82887 13616 2 1780.87686 891.4433 Voltage-dependent P\Q-type calcium channel subunit alpha-1A OS=Homo sapiens OX=9606 GN=CACNA1A PE=1 SV=3 6.8 2418.8 - 795234 - - - 2.7582 - 1.771 0.257 - 118.4 1 1 0 0.0049 18 0 0 0 0.00E+00 4.74E+07 - - - 2.3428 0.9999 221125_WJC_METTL3_EV_vs_WT_F06.13617.13617.4 0.00181 Oct-84 K.FLQEHGSDSFLAEHK[136.11].L sp|Q00688|FKBP3_HUMAN 1 1751.8358 0.17 82888 13617 4 1751.835113 438.9662 Peptidyl-prolyl cis-trans isomerase FKBP3 OS=Homo sapiens OX=9606 GN=FKBP3 PE=1 SV=1 5.27 2418.8 - 3.00E+06 - - - -0.4201 - 1.759 0.422 - 94.5 1 2 0 -0.0007 15 0 0 0 1.14E+07 6.70E+07 - - - 3.101 0.9928 221125_WJC_METTL3_EV_vs_WT_F06.13622.13622.3 0.0171 17/44 K.GK[136.11]VEEVELPVEK[136.11].V "sp|Q99873|ANM1_HUMAN,sp|Q9NR22|ANM8_HUMAN,tr|E9PQ98|E9PQ98_HUMAN,tr|E9PKG1|E9PKG1_HUMAN,tr|E9PNR9|E9PNR9_HUMAN,tr|H0YDE4|H0YDE4_HUMAN,tr|E9PIX6|E9PIX6_HUMAN" 7 1370.7628 2.15 82893 13622 3 1370.76614 457.9282 Protein arginine N-methyltransferase 1 OS=Homo sapiens OX=9606 GN=PRMT1 PE=1 SV=3 4.49 2419.5 - 1.22E+06 - - - 2.4388 - 2.807 0.204 - 441.3 1 2 1 0.0033 12 0 0 0 1.84E+08 8.55E+07 - - - 3.6743 1 221125_WJC_METTL3_EV_vs_WT_F06.13629.13629.3 9.46E-06 14/44 K.YNIWC[160.03]STEHGNK[136.11].R sp|Q9Y5A9|YTHD2_HUMAN 1 1515.6656 1.31 82898 13629 3 1515.668052 506.2291 YTH domain-containing family protein 2 OS=Homo sapiens OX=9606 GN=YTHDF2 PE=1 SV=2 6.74 2420.3 - 6.95E+06 - - - 1.6099 - 2.293 0.563 - 161.3 1 2 0 0.0024 12 0 0 0 2.68E+08 2.04E+08 - - - 7.1165 0.9995 221125_WJC_METTL3_EV_vs_WT_F06.13638.13638.3 0.00109 Dec-44 K.GKVEEVELPVEK.V "sp|Q99873|ANM1_HUMAN,sp|Q9NR22|ANM8_HUMAN,tr|E9PQ98|E9PQ98_HUMAN,tr|E9PKG1|E9PKG1_HUMAN,tr|E9PNR9|E9PNR9_HUMAN,tr|H0YDE4|H0YDE4_HUMAN,tr|E9PIX6|E9PIX6_HUMAN" 7 1354.7344 2.05 82905 13638 3 1354.733373 452.5854 Protein arginine N-methyltransferase 1 OS=Homo sapiens OX=9606 GN=PRMT1 PE=1 SV=3 4.49 2421.3 - 6.67E+06 - - - -0.7559 - 2.571 0.357 - 256.6 1 2 1 -0.001 12 0 0 0 1.84E+08 9.01E+07 - - - 5.1374 0.8742 221125_WJC_METTL3_EV_vs_WT_F06.13639.13639.3 0.0197 13/48 T.YSLGSALR[166.11]PSTSR[166.11].S "sp|P08670|VIME_HUMAN,tr|B0YJC4|B0YJC4_HUMAN,tr|A0A1B0GVG8|A0A1B0GVG8_HUMAN,tr|A0A1B0GTT5|A0A1B0GTT5_HUMAN" 4 1413.7479 1.74 82906 13639 3 1413.747874 472.2566 Vimentin OS=Homo sapiens OX=9606 GN=VIM PE=1 SV=4 10.84 2421.3 - 2.89E+06 - - - -0.0304 - 1.862 0.257 - 168.1 1 1 0 0 13 0 0 0 2.50E+08 1.44E+08 - - - 3.0908 0.9999 221125_WJC_METTL3_EV_vs_WT_F06.13640.13640.3 0.000284 16/48 R.VAIHYINPPNPAK.D "sp|P78406|RAE1L_HUMAN,tr|E9PQ57|E9PQ57_HUMAN" 2 1432.7827 1.92 82907 13640 3 1432.781387 478.6015 mRNA export factor OS=Homo sapiens OX=9606 GN=RAE1 PE=1 SV=1 8.57 2421.4 - 2.51E+06 - - - -0.9052 - 2.62 0.353 - 324.7 1 2 0 -0.0013 13 0 0 0 6.07E+07 3.16E+07 - - - 5.0867 0.9999 221125_WJC_METTL3_EV_vs_WT_F06.13641.13641.3 9.29E-05 15/64 R.TPAPEPEPC[160.03]EASELPAK.R "sp|Q9ULV3|CIZ1_HUMAN,tr|Q5SYW2|Q5SYW2_HUMAN,tr|F5H2X7|F5H2X7_HUMAN,tr|H0Y5D5|H0Y5D5_HUMAN,tr|A0A494C0L7|A0A494C0L7_HUMAN,tr|Q9BTG3|Q9BTG3_HUMAN" 6 1821.8455 2.24 82908 13641 3 1821.844819 608.2891 Cip1-interacting zinc finger protein OS=Homo sapiens OX=9606 GN=CIZ1 PE=1 SV=2 4.09 2421.6 - 1.22E+06 - - - -0.3634 - 2.51 0.37 - 305.5 1 2 0 -0.0007 17 0 0 0 2.23E+07 9.94E+06 - - - 4.9899 0.9999 221125_WJC_METTL3_EV_vs_WT_F06.13648.13648.3 1.12E-06 13/48 R.TGLYNYYDDEK[136.11]EK[136.11].L "sp|P50454|SERPH_HUMAN,tr|E9PKH2|E9PKH2_HUMAN,tr|E9PPV6|E9PPV6_HUMAN,tr|E9PR70|E9PR70_HUMAN,tr|E9PJH8|E9PJH8_HUMAN" 5 1652.7541 1.64 82913 13648 3 1652.752243 551.9253 Serpin H1 OS=Homo sapiens OX=9606 GN=SERPINH1 PE=1 SV=2 4.32 2422.4 - 2.21E+06 - - - -1.1133 - 2.689 0.513 - 116.3 1 2 1 -0.0018 13 0 0 0 1.84E+08 1.12E+08 - - - 6.9409 0.8856 221125_WJC_METTL3_EV_vs_WT_F06.13650.13650.4 0.00105 Dec-78 K.TVVNK[136.11]DVFR[166.11]DPALK[136.11].R "sp|P61353|RL27_HUMAN,tr|K7ELC7|K7ELC7_HUMAN" 2 1626.9304 0.82 82915 13650 4 1626.930084 407.7399 60S ribosomal protein L27 OS=Homo sapiens OX=9606 GN=RPL27 PE=1 SV=2 8.26 2422.6 - 1.53E+06 - - - -0.1703 - 1.951 0.15 - 70.2 1 2 2 -0.0003 14 0 0 0 1.47E+07 1.80E+07 - - - 0.7748 0.9845 221125_WJC_METTL3_EV_vs_WT_F06.13651.13651.3 0.000236 16/60 K.ISSNPNPVVQMSVGHK.A "sp|A0FGR8|ESYT2_HUMAN,tr|A0A499FIX8|A0A499FIX8_HUMAN,tr|H7BXI1|H7BXI1_HUMAN,tr|A0A087WXU3|A0A087WXU3_HUMAN" 4 1692.8617 0.68 82916 13651 3 1692.856678 565.2945 Extended synaptotagmin-2 OS=Homo sapiens OX=9606 GN=ESYT2 PE=1 SV=1 8.76 2422.8 - 957145 - - - -2.9896 - 2.571 0.124 - 221.9 1 2 0 -0.0051 16 0 0 0 1.77E+07 2.62E+07 - - - 2.344 0.9984 221125_WJC_METTL3_EV_vs_WT_F06.13653.13653.2 0.00047 15/22 K.GK[136.11]VEEVELPVEK[136.11].V "sp|Q99873|ANM1_HUMAN,sp|Q9NR22|ANM8_HUMAN,tr|E9PQ98|E9PQ98_HUMAN,tr|E9PKG1|E9PKG1_HUMAN,tr|E9PNR9|E9PNR9_HUMAN,tr|H0YDE4|H0YDE4_HUMAN,tr|E9PIX6|E9PIX6_HUMAN" 7 1370.7628 2.42 82918 13653 2 1370.764542 686.3887 Protein arginine N-methyltransferase 1 OS=Homo sapiens OX=9606 GN=PRMT1 PE=1 SV=3 4.49 2423 - 598963 - - - 1.273 - 2.719 0.494 - 416.4 1 2 1 0.0017 12 0 0 0 3.38E+07 1.40E+07 - - - 5.321 1 221125_WJC_METTL3_EV_vs_WT_F06.13655.13655.2 2.94E-06 30-Nov K.QNVPSGGPVPSPQTYR[166.11].P "sp|Q5JSZ5|PRC2B_HUMAN,tr|A0A804HKU3|A0A804HKU3_HUMAN,tr|A0A804HJR4|A0A804HJR4_HUMAN" 3 1692.8459 2.17 82920 13655 2 1692.837831 847.4302 Protein PRRC2B OS=Homo sapiens OX=9606 GN=PRRC2B PE=1 SV=2 8.75 2423.3 - 291076 - - - -4.7683 - 2.276 0.631 - 263.5 1 1 0 -0.0081 16 0 0 0 2.93E+07 1.35E+07 - - - 5.721 0.9999 221125_WJC_METTL3_EV_vs_WT_F06.13658.13658.3 0.000154 Dec-48 R.TGLYNYYDDEKEK.L "sp|P50454|SERPH_HUMAN,tr|E9PKH2|E9PKH2_HUMAN,tr|E9PPV6|E9PPV6_HUMAN,tr|E9PR70|E9PR70_HUMAN,tr|E9PJH8|E9PJH8_HUMAN" 5 1636.7257 1.64 82921 13658 3 1636.724075 546.5825 Serpin H1 OS=Homo sapiens OX=9606 GN=SERPINH1 PE=1 SV=2 4.32 2423.7 - 6.15E+06 - - - -0.9824 - 2.306 0.611 - 123.5 1 2 1 -0.0016 13 0 0 0 1.84E+08 1.12E+08 - - - 7.6169 1 221125_WJC_METTL3_EV_vs_WT_F06.13660.13660.4 4.12E-08 16/84 R.LLHVAVSDVNDDVR[166.11]R[166.11].A "sp|Q99460|PSMD1_HUMAN,tr|A0A7I2V4X0|A0A7I2V4X0_HUMAN,tr|A0A7I2V2K8|A0A7I2V2K8_HUMAN,tr|A0A7I2YQY1|A0A7I2YQY1_HUMAN,tr|A0A7I2V523|A0A7I2V523_HUMAN,tr|A0A7I2V641|A0A7I2V641_HUMAN,tr|A0A7I2YQI9|A0A7I2YQI9_HUMAN,tr|A0A7I2V262|A0A7I2V262_HUMAN,tr|A0A087WW66|A0A087WW66_HUMAN,tr|A0A7P0MW50|A0A7P0MW50_HUMAN,tr|A0A7I2V5C8|A0A7I2V5C8_HUMAN" 11 1726.9229 0.81 82923 13660 4 1726.923447 432.738 26S proteasome non-ATPase regulatory subunit 1 OS=Homo sapiens OX=9606 GN=PSMD1 PE=1 SV=2 5.3 2423.8 - 2.48E+06 - - - 0.3046 - 3.09 0.578 - 285.2 1 2 0 0.0005 15 0 0 0 2.10E+07 2.60E+07 - - - 4.6604 1 221125_WJC_METTL3_EV_vs_WT_F06.13661.13661.3 8.19E-07 17/56 R.LLHVAVSDVNDDVR[166.11]R[166.11].A "sp|Q99460|PSMD1_HUMAN,tr|A0A7I2V4X0|A0A7I2V4X0_HUMAN,tr|A0A7I2V2K8|A0A7I2V2K8_HUMAN,tr|A0A7I2YQY1|A0A7I2YQY1_HUMAN,tr|A0A7I2V523|A0A7I2V523_HUMAN,tr|A0A7I2V641|A0A7I2V641_HUMAN,tr|A0A7I2YQI9|A0A7I2YQI9_HUMAN,tr|A0A7I2V262|A0A7I2V262_HUMAN,tr|A0A087WW66|A0A087WW66_HUMAN,tr|A0A7P0MW50|A0A7P0MW50_HUMAN,tr|A0A7I2V5C8|A0A7I2V5C8_HUMAN" 11 1726.9229 0.6 82924 13661 3 1726.924172 576.6483 26S proteasome non-ATPase regulatory subunit 1 OS=Homo sapiens OX=9606 GN=PSMD1 PE=1 SV=2 5.3 2423.9 - 1.80E+06 - - - 0.7244 - 2.842 0.58 - 390.3 1 2 0 0.0013 15 0 0 0 1.40E+07 2.34E+07 - - - 7.7316 0.9996 221125_WJC_METTL3_EV_vs_WT_F06.13662.13662.3 2.02E-05 Nov-40 R.C[160.03]STEQFTHAFR.T "sp|Q86UK7|ZN598_HUMAN,tr|H3BQQ2|H3BQQ2_HUMAN,tr|H3BPG6|H3BPG6_HUMAN" 3 1382.6037 0.56 82925 13662 3 1382.609294 461.8752 E3 ubiquitin-protein ligase ZNF598 OS=Homo sapiens OX=9606 GN=ZNF598 PE=1 SV=1 6.74 2423.9 - 1.69E+06 - - - 4.0214 - 1.991 0.488 - 169.8 1 2 0 0.0056 11 0 0 0 1.23E+07 2.19E+07 - - - 5.9355 0.9998 221125_WJC_METTL3_EV_vs_WT_F06.13663.13663.3 0.00453 14/32 R.KQVEELFER.K "sp|P78347|GTF2I_HUMAN,tr|A0A494C1K3|A0A494C1K3_HUMAN" 2 1176.6139 1.41 82926 13663 3 1176.612156 393.2119 General transcription factor II-I OS=Homo sapiens OX=9606 GN=GTF2I PE=1 SV=2 4.79 2424 - 1.50E+06 - - - -1.472 - 2.653 0.315 - 349 1 2 0 -0.0017 9 0 0 0 2.45E+07 1.73E+07 - - - 4.992 1 221125_WJC_METTL3_EV_vs_WT_F06.13664.13664.3 5.27E-10 25/72 K.VDATRPEATTEVGPQIGVK.E sp|Q96T58|MINT_HUMAN 1 1967.0324 1.43 82927 13664 3 1967.03281 656.6847 Msx2-interacting protein OS=Homo sapiens OX=9606 GN=SPEN PE=1 SV=1 4.68 2424.2 - 1.08E+06 - - - 0.2237 - 4.282 0.592 - 706.9 1 2 0 0.0004 19 0 0 0 3.48E+07 2.43E+07 - - - 8.7133 1 221125_WJC_METTL3_EV_vs_WT_F06.13665.13665.3 1.13E-10 18/56 K.INEKPQVIADYESGR.A sp|O60869|EDF1_HUMAN 1 1717.8635 0.55 82928 13665 3 1717.863729 573.6284 Endothelial differentiation-related factor 1 OS=Homo sapiens OX=9606 GN=EDF1 PE=1 SV=1 4.68 2424.3 - 981523 - - - 0.1252 - 3.102 0.611 - 417.7 1 2 0 0.0002 15 0 0 0 4.33E+07 7.83E+07 - - - 8.3059 0.9814 221125_WJC_METTL3_EV_vs_WT_F06.13672.13672.3 0.124 Sep-56 K.AKPASGLDGNFNSIR.M "sp|Q86UP3|ZFHX4_HUMAN,tr|E7EVZ1|E7EVZ1_HUMAN" 2 1545.79 2.43 82933 13672 3 1545.787545 516.2706 Zinc finger homeobox protein 4 OS=Homo sapiens OX=9606 GN=ZFHX4 PE=1 SV=1 8.79 2425.1 - 1.49E+06 - - - -1.5591 - 1.569 0.17 - 79.3 1 2 0 -0.0024 15 0 0 0 3.04E+07 1.25E+07 - - - 1.61 0.9999 221125_WJC_METTL3_EV_vs_WT_F06.13673.13673.3 6.26E-09 17/56 K.INEK[136.11]PQVIADYESGR[166.11].A sp|O60869|EDF1_HUMAN 1 1735.886 0.55 82934 13673 3 1735.884471 579.6359 Endothelial differentiation-related factor 1 OS=Homo sapiens OX=9606 GN=EDF1 PE=1 SV=1 4.68 2425.2 - 4.11E+06 - - - -0.8716 - 2.973 0.403 - 443.8 1 2 0 -0.0015 15 0 0 0 4.33E+07 7.83E+07 - - - 5.8757 0.9989 221125_WJC_METTL3_EV_vs_WT_F06.13674.13674.2 0.000638 18/22 K.GKVEEVELPVEK.V "sp|Q99873|ANM1_HUMAN,sp|Q9NR22|ANM8_HUMAN,tr|E9PQ98|E9PQ98_HUMAN,tr|E9PKG1|E9PKG1_HUMAN,tr|E9PNR9|E9PNR9_HUMAN,tr|H0YDE4|H0YDE4_HUMAN,tr|E9PIX6|E9PIX6_HUMAN" 7 1354.7344 2.42 82935 13674 2 1354.73314 678.3745 Protein arginine N-methyltransferase 1 OS=Homo sapiens OX=9606 GN=PRMT1 PE=1 SV=3 4.49 2425.3 - 1.83E+06 - - - -0.9279 - 2.833 0.51 - 1202.6 1 2 1 -0.0013 12 0 0 0 3.38E+07 1.40E+07 - - - 5.5474 0.9998 221125_WJC_METTL3_EV_vs_WT_F06.13675.13675.3 2.46E-06 Dec-44 K.KQQISLATQMVR.M "sp|P48643|TCPE_HUMAN,tr|E9PCA1|E9PCA1_HUMAN,tr|B7ZAR1|B7ZAR1_HUMAN,tr|E7ENZ3|E7ENZ3_HUMAN" 4 1401.7762 0.55 82936 13675 3 1401.780766 468.266 T-complex protein 1 subunit epsilon OS=Homo sapiens OX=9606 GN=CCT5 PE=1 SV=1 11 2425.4 - 1.26E+06 - - - 3.2437 - 2.81 0.423 - 284.6 1 2 0 0.0045 12 0 0 0 1.58E+08 2.90E+08 - - - 6.1186 0.9966 221125_WJC_METTL3_EV_vs_WT_F06.13680.13680.2 0.000308 24-Sep R.TGLYNYYDDEK[136.11]EK[136.11].L "sp|P50454|SERPH_HUMAN,tr|E9PKH2|E9PKH2_HUMAN,tr|E9PPV6|E9PPV6_HUMAN,tr|E9PR70|E9PR70_HUMAN,tr|E9PJH8|E9PJH8_HUMAN" 5 1652.7541 1.69 82941 13680 2 1652.757796 827.3843 Serpin H1 OS=Homo sapiens OX=9606 GN=SERPINH1 PE=1 SV=2 4.32 2425.9 - 325375 - - - 2.2466 - 2.24 0.526 - 240.9 1 2 1 0.0037 13 0 0 0 8.97E+06 5.32E+06 - - - 4.9947 0.9976 221125_WJC_METTL3_EV_vs_WT_F06.13681.13681.2 0.000842 Jun-32 R.TPAPEPEPC[160.03]EASELPAK[136.11].R "sp|Q9ULV3|CIZ1_HUMAN,tr|Q5SYW2|Q5SYW2_HUMAN,tr|F5H2X7|F5H2X7_HUMAN,tr|H0Y5D5|H0Y5D5_HUMAN,tr|A0A494C0L7|A0A494C0L7_HUMAN,tr|Q9BTG3|Q9BTG3_HUMAN" 6 1829.8597 4.87 82942 13681 2 1829.852739 915.9371 Cip1-interacting zinc finger protein OS=Homo sapiens OX=9606 GN=CIZ1 PE=1 SV=2 4.09 2426 - 0 - - - -3.7937 - 1.453 0.487 - 42.1 1 2 0 -0.0069 17 0 0 0 4.21E+07 8.63E+06 - - - 3.5544 0.8969 221125_WJC_METTL3_EV_vs_WT_F06.13684.13684.3 0.0152 Oct-48 T.YSLGSALRPSTSR.S "sp|P08670|VIME_HUMAN,tr|B0YJC4|B0YJC4_HUMAN,tr|A0A1B0GVG8|A0A1B0GVG8_HUMAN,tr|A0A1B0GTT5|A0A1B0GTT5_HUMAN" 4 1393.7314 1.74 82943 13684 3 1393.73181 465.5844 Vimentin OS=Homo sapiens OX=9606 GN=VIM PE=1 SV=4 10.84 2426.5 - 1.46E+07 - - - 0.3107 - 1.716 0.291 - 117.1 1 1 0 0.0004 13 0 0 0 2.51E+08 1.44E+08 - - - 3.2483 1 221125_WJC_METTL3_EV_vs_WT_F06.13686.13686.2 2.62E-05 16/22 K.K[136.11]QQISLATQMVR[166.11].M "sp|P48643|TCPE_HUMAN,tr|E9PCA1|E9PCA1_HUMAN,tr|B7ZAR1|B7ZAR1_HUMAN,tr|E7ENZ3|E7ENZ3_HUMAN" 4 1419.7987 0.54 82945 13686 2 1419.802872 710.9066 T-complex protein 1 subunit epsilon OS=Homo sapiens OX=9606 GN=CCT5 PE=1 SV=1 11 2426.7 - 1.03E+06 - - - 2.9462 - 2.893 0.547 - 1102.6 1 2 0 0.0042 12 0 0 0 2.08E+07 3.82E+07 - - - 5.8749 1 221125_WJC_METTL3_EV_vs_WT_F06.13688.13688.4 5.27E-06 15/60 R.EIEHVMYHDWR[166.11].L "sp|P82930|RT34_HUMAN,tr|C9JJ19|C9JJ19_HUMAN" 2 1523.6855 0.03 82947 13688 4 1523.684951 381.9287 "28S ribosomal protein S34, mitochondrial OS=Homo sapiens OX=9606 GN=MRPS34 PE=1 SV=2" 5.28 2426.9 - 676132 - - - -0.3623 - 2.448 0.501 - 249.1 1 2 0 -0.0006 11 0 0 0 5.19E+05 1.78E+07 - - - 3.9331 1 221125_WJC_METTL3_EV_vs_WT_F06.13690.13690.2 1.92E-08 17/32 R.LSQVSDSVSGQTVVDPK.G sp|O94906|PRP6_HUMAN 1 1744.8843 2.8 82949 13690 2 1744.882826 873.4494 Pre-mRNA-processing factor 6 OS=Homo sapiens OX=9606 GN=PRPF6 PE=1 SV=1 4.21 2427.2 - 510829 - - - -0.8499 - 3.315 0.637 - 667.6 1 2 0 -0.0015 17 0 0 0 8.50E+07 3.04E+07 - - - 6.6919 0.9998 221125_WJC_METTL3_EV_vs_WT_F06.13691.13691.2 9.01E-05 22-Aug R.LTWHSC[160.03]PEDEAQ.- sp|Q13185|CBX3_HUMAN 1 1471.6038 - 82950 13691 2 1471.601542 736.8092 Chromobox protein homolog 3 OS=Homo sapiens OX=9606 GN=CBX3 PE=1 SV=4 4.13 2427.3 - 344038 - - - -1.5303 - 1.8 0.571 - 165.1 1 2 0 -0.0023 12 0 0 0 - - - - - 4.8043 1 221125_WJC_METTL3_EV_vs_WT_F06.13694.13694.3 1.80E-08 16/44 K.K[136.11]QQISLATQMVR[166.11].M "sp|P48643|TCPE_HUMAN,tr|E9PCA1|E9PCA1_HUMAN,tr|B7ZAR1|B7ZAR1_HUMAN,tr|E7ENZ3|E7ENZ3_HUMAN" 4 1419.7987 0.55 82951 13694 3 1419.799242 474.2735 T-complex protein 1 subunit epsilon OS=Homo sapiens OX=9606 GN=CCT5 PE=1 SV=1 11 2427.7 - 1.66E+07 - - - 0.3895 - 3.031 0.565 - 645.3 1 2 0 0.0006 12 0 0 0 1.58E+08 2.90E+08 - - - 7.9127 0.9994 221125_WJC_METTL3_EV_vs_WT_F06.13700.13700.3 0.000111 14/68 K.FVTSTSDHFVEGQTVAAK[136.11].V "sp|Q14690|RRP5_HUMAN,tr|A0A3B3IUD7|A0A3B3IUD7_HUMAN" 2 1930.9516 0.69 82957 13700 3 1930.958291 644.6578 Protein RRP5 homolog OS=Homo sapiens OX=9606 GN=PDCD11 PE=1 SV=3 5.32 2428.2 - 759997 - - - 3.4615 - 2.057 0.426 - 70.9 1 2 0 0.0067 18 0 0 0 1.29E+07 1.87E+07 - - - 5.0836 0.9999 221125_WJC_METTL3_EV_vs_WT_F06.13701.13701.2 4.29E-08 17/32 R.LSQVSDSVSGQTVVDPK[136.11].G sp|O94906|PRP6_HUMAN 1 1752.8985 2.69 82958 13701 2 1752.900552 877.4565 Pre-mRNA-processing factor 6 OS=Homo sapiens OX=9606 GN=PRPF6 PE=1 SV=1 4.21 2428.3 - 489958 - - - 1.1655 - 3.2 0.467 - 647.6 1 2 0 0.002 17 0 0 0 8.13E+07 3.02E+07 - - - 5.3493 0.9998 221125_WJC_METTL3_EV_vs_WT_F06.13703.13703.2 1.43E-05 16/26 R.HQSFVLVGETGSGK.T sp|O43143|DHX15_HUMAN 1 1444.731 1.12 82960 13703 2 1444.733553 723.3728 Pre-mRNA-splicing factor ATP-dependent RNA helicase DHX15 OS=Homo sapiens OX=9606 GN=DHX15 PE=1 SV=2 6.75 2428.6 - 426016 - - - 1.7373 - 2.664 0.557 - 682.9 1 2 0 0.0025 14 0 0 0 1.04E+07 9.26E+06 - - - 5.613 0.8141 221125_WJC_METTL3_EV_vs_WT_F06.13704.13704.2 11.9 12-Jul L.PLVPVKR.Q sp|Q96DI7|SNR40_HUMAN 1 807.5331 2.28 82961 13704 2 807.532924 404.7738 U5 small nuclear ribonucleoprotein 40 kDa protein OS=Homo sapiens OX=9606 GN=SNRNP40 PE=1 SV=1 11.01 2428.7 - 412957 - - - -0.1659 - 1.597 0.105 - 225.1 1 1 0 -0.0001 7 0 0 0 3.04E+07 1.33E+07 - - - 1.2998 1 221125_WJC_METTL3_EV_vs_WT_F06.13709.13709.3 1.68E-07 13/48 R.K[136.11]ASGPPVSELITK[136.11].A "sp|P10412|H14_HUMAN,sp|P16403|H12_HUMAN,sp|P16402|H13_HUMAN" 3 1341.7839 0.81 82964 13709 3 1341.784976 448.2686 Histone H1.4 OS=Homo sapiens OX=9606 GN=H1-4 PE=1 SV=2 8.59 2429.3 - 3.00E+07 - - - 0.8265 - 2.851 0.582 - 278.2 1 2 0 0.0011 13 0 0 0 5.60E+08 6.94E+08 - - - 7.869 1 221125_WJC_METTL3_EV_vs_WT_F06.13710.13710.3 0.000254 13/52 R.HQSFVLVGETGSGK[136.11].T sp|O43143|DHX15_HUMAN 1 1452.7452 1.04 82965 13710 3 1452.745161 485.2557 Pre-mRNA-splicing factor ATP-dependent RNA helicase DHX15 OS=Homo sapiens OX=9606 GN=DHX15 PE=1 SV=2 6.75 2429.4 - 3.57E+06 - - - -0.0564 - 2.947 0.532 - 331.6 1 2 0 -0.0001 14 0 0 0 7.36E+07 7.11E+07 - - - 7.3435 1 221125_WJC_METTL3_EV_vs_WT_F06.13711.13711.3 1.91E-06 13/40 R.EIEHVMYHDWR[166.11].L "sp|P82930|RT34_HUMAN,tr|C9JJ19|C9JJ19_HUMAN" 2 1523.6855 1.02 82966 13711 3 1523.682411 508.9024 "28S ribosomal protein S34, mitochondrial OS=Homo sapiens OX=9606 GN=MRPS34 PE=1 SV=2" 5.28 2429.4 - 3.75E+06 - - - -2.0293 - 2.446 0.532 - 240.8 1 2 0 -0.0031 11 0 0 0 3.65E+07 3.57E+07 - - - 7.0114 1 221125_WJC_METTL3_EV_vs_WT_F06.13712.13712.3 5.30E-05 14/44 R.KGPELPLVPVKR.Q sp|Q96DI7|SNR40_HUMAN 1 1331.8289 2.12 82967 13712 3 1331.827716 444.9502 U5 small nuclear ribonucleoprotein 40 kDa protein OS=Homo sapiens OX=9606 GN=SNRNP40 PE=1 SV=1 9.99 2429.5 - 1.38E+06 - - - -0.8935 - 2.804 0.544 - 325 1 2 0 -0.0012 12 0 0 0 7.76E+07 3.66E+07 - - - 7.4626 0.9997 221125_WJC_METTL3_EV_vs_WT_F06.13716.13716.3 3.72E-05 13/52 R.FK[136.11]GYQQQDSQELLR[166.11].Y sp|Q9Y5T5|UBP16_HUMAN 1 1756.8863 0.85 82971 13716 3 1756.887349 586.636 Ubiquitin carboxyl-terminal hydrolase 16 OS=Homo sapiens OX=9606 GN=USP16 PE=1 SV=1 6.07 2429.9 - 889453 - - - 0.5868 - 2.393 0.44 - 198.4 1 2 1 0.001 14 0 0 0 1.97E+07 2.31E+07 - - - 5.7641 0.9591 221125_WJC_METTL3_EV_vs_WT_F06.13721.13721.4 0.0698 Nov-72 K.LVNNGEK[136.11]LEFLHK[136.11].T sp|Q15393|SF3B3_HUMAN 1 1555.8693 1.22 82976 13721 4 1555.867613 389.9746 Splicing factor 3B subunit 3 OS=Homo sapiens OX=9606 GN=SF3B3 PE=1 SV=4 6.76 2430.6 - 334076 - - - -1.1023 - 1.92 0.193 - 79.1 1 2 1 -0.0017 13 0 0 0 8.27E+06 6.79E+06 - - - 1.1473 0.9999 221125_WJC_METTL3_EV_vs_WT_F06.13722.13722.2 6.18E-06 Aug-32 K.DSMSAAEVGTGQYATTK[136.11].G "tr|A0A1B0GTF8|A0A1B0GTF8_HUMAN,tr|A0A0A0MRA8|A0A0A0MRA8_HUMAN,tr|A0A0J9YW26|A0A0J9YW26_HUMAN,tr|A8K968|A8K968_HUMAN,tr|J3KT37|J3KT37_HUMAN,tr|A0A0A0MSA4|A0A0A0MSA4_HUMAN" 6 1723.7814 0.26 82977 13722 2 1723.78202 862.898 Band 4.1-like protein 3 OS=Homo sapiens OX=9606 GN=EPB41L3 PE=1 SV=1 4.37 2430.7 - 213972 - - - 0.3423 - 2.034 0.591 - 140.2 1 2 0 0.0006 17 0 0 0 7.84E+05 3.00E+06 - - - 5.1515 1 221125_WJC_METTL3_EV_vs_WT_F06.13725.13725.3 4.64E-05 15/44 K.DAC[160.03]VISSDFHER.D sp|Q99805|TM9S2_HUMAN 1 1434.6198 1.09 82978 13725 3 1434.621409 479.2139 Transmembrane 9 superfamily member 2 OS=Homo sapiens OX=9606 GN=TM9SF2 PE=1 SV=1 4.54 2431.1 - 6.14E+06 - - - 1.1369 - 2.899 0.469 - 483.8 1 2 0 0.0016 12 0 0 0 9.21E+07 8.44E+07 - - - 6.7187 1 221125_WJC_METTL3_EV_vs_WT_F06.13726.13726.3 2.17E-07 16/40 R.EIEHVMYHDWR.L "sp|P82930|RT34_HUMAN,tr|C9JJ19|C9JJ19_HUMAN" 2 1513.6772 1.02 82979 13726 3 1513.678508 505.5664 "28S ribosomal protein S34, mitochondrial OS=Homo sapiens OX=9606 GN=MRPS34 PE=1 SV=2" 5.28 2431.1 - 4.14E+06 - - - 0.8423 - 2.591 0.568 - 435.8 1 2 0 0.0013 11 0 0 0 3.65E+07 3.57E+07 - - - 7.5769 0.9998 221125_WJC_METTL3_EV_vs_WT_F06.13727.13727.2 6.44E-05 20-Nov K.ASLENSLEETK.G "sp|P02533|K1C14_HUMAN,sp|P08779|K1C16_HUMAN,tr|K7ENW6|K7ENW6_HUMAN" 3 1219.5932 999 82980 13727 2 1219.59427 610.8039 "Keratin, type I cytoskeletal 14 OS=Homo sapiens OX=9606 GN=KRT14 PE=1 SV=4" 4.25 2431.2 - 5.27E+06 - - - 0.8675 - 2.372 0.469 - 359.9 1 2 0 0.0011 11 0 0 0 5.03E+07 0.00E+00 - - - 4.8413 1 221125_WJC_METTL3_EV_vs_WT_F06.13728.13728.2 1.00E-05 17/22 K.KQQISLATQMVR.M "sp|P48643|TCPE_HUMAN,tr|E9PCA1|E9PCA1_HUMAN,tr|B7ZAR1|B7ZAR1_HUMAN,tr|E7ENZ3|E7ENZ3_HUMAN" 4 1401.7762 0.54 82981 13728 2 1401.776141 701.8954 T-complex protein 1 subunit epsilon OS=Homo sapiens OX=9606 GN=CCT5 PE=1 SV=1 11 2431.3 - 1.91E+06 - - - -0.0556 - 3.113 0.52 - 1152.7 1 2 0 -0.0001 12 0 0 0 2.08E+07 3.82E+07 - - - 5.8696 0.9994 221125_WJC_METTL3_EV_vs_WT_F06.13729.13729.3 4.97E-05 15/60 K.VTVAGLAGK[136.11]DPVQC[160.03]SR[166.11].D "sp|Q99497|PARK7_HUMAN,tr|K7ELW0|K7ELW0_HUMAN" 2 1674.8842 2.29 82982 13729 3 1674.880411 559.302 Parkinson disease protein 7 OS=Homo sapiens OX=9606 GN=PARK7 PE=1 SV=2 8.19 2431.3 - 1.01E+06 - - - -2.2682 - 2.432 0.447 - 197.2 1 2 1 -0.0038 16 0 0 0 1.22E+09 5.35E+08 - - - 5.8029 0.9997 221125_WJC_METTL3_EV_vs_WT_F06.13730.13730.3 0.0122 Oct-40 R.ESVDHLTIPSR[166.11].C "sp|P41252|SYIC_HUMAN,tr|A0A804HL54|A0A804HL54_HUMAN,tr|A0A804HKU1|A0A804HKU1_HUMAN,tr|A0A804HK69|A0A804HK69_HUMAN,tr|A0A804HIV9|A0A804HIV9_HUMAN,tr|A0A804HJN6|A0A804HJN6_HUMAN,tr|A0A804HHW9|A0A804HHW9_HUMAN,tr|A0A0A0MSX9|A0A0A0MSX9_HUMAN,tr|J3KR24|J3KR24_HUMAN,tr|A0A804HJ36|A0A804HJ36_HUMAN" 10 1262.6494 0.81 82983 13730 3 1262.648689 421.8904 "Isoleucine--tRNA ligase, cytoplasmic OS=Homo sapiens OX=9606 GN=IARS1 PE=1 SV=2" 5.32 2431.4 - 961834 - - - -0.5908 - 2.215 0.297 - 152.8 1 2 0 -0.0007 11 0 0 0 1.01E+08 1.25E+08 - - - 4.1102 0.9997 221125_WJC_METTL3_EV_vs_WT_F06.13734.13734.3 0.00166 Nov-36 R.ETYTEDFIKK.Q sp|P82933|RT09_HUMAN 1 1272.6238 0.89 82987 13734 3 1272.625426 425.2152 "28S ribosomal protein S9, mitochondrial OS=Homo sapiens OX=9606 GN=MRPS9 PE=1 SV=2" 4.68 2432 - 732366 - - - 1.2902 - 1.911 0.349 - 116.3 1 2 0 0.0016 10 0 0 0 4.99E+06 5.58E+06 - - - 4.3219 0.9999 221125_WJC_METTL3_EV_vs_WT_F06.13735.13735.3 0.000608 Nov-36 R.ETYTEDFIK[136.11]K[136.11].Q sp|P82933|RT09_HUMAN 1 1288.6522 0.89 82988 13735 3 1288.652703 430.558 "28S ribosomal protein S9, mitochondrial OS=Homo sapiens OX=9606 GN=MRPS9 PE=1 SV=2" 4.68 2432.1 - 708263 - - - 0.4027 - 2.02 0.396 - 125.1 1 2 0 0.0005 10 0 0 0 4.99E+06 5.58E+06 - - - 5.0082 0.9999 221125_WJC_METTL3_EV_vs_WT_F06.13736.13736.2 0.0028 22-Nov K.DAC[160.03]VISSDFHER.D sp|Q99805|TM9S2_HUMAN 1 1434.6198 0.89 82989 13736 2 1434.619171 718.3172 Transmembrane 9 superfamily member 2 OS=Homo sapiens OX=9606 GN=TM9SF2 PE=1 SV=1 4.54 2432.2 - 662807 - - - -0.4231 - 2.33 0.572 - 493.9 1 2 0 -0.0006 12 0 0 0 9.29E+06 1.05E+07 - - - 5.4912 0.9918 221125_WJC_METTL3_EV_vs_WT_F06.13738.13738.4 1.10E-05 15/72 K.LVNNGEKLEFLHK.T sp|Q15393|SF3B3_HUMAN 1 1539.8409 1.14 82991 13738 4 1539.842452 385.9675 Splicing factor 3B subunit 3 OS=Homo sapiens OX=9606 GN=SF3B3 PE=1 SV=4 6.76 2432.5 - 585610 - - - 0.9897 - 2.699 0.248 - 170.6 1 2 1 0.0015 13 0 0 0 8.38E+06 7.36E+06 - - - 1.7523 0.9999 221125_WJC_METTL3_EV_vs_WT_F06.13743.13743.3 0.00181 15/44 K.DAC[160.03]VISSDFHER[166.11].D sp|Q99805|TM9S2_HUMAN 1 1444.628 1.08 82994 13743 3 1444.631234 482.55 Transmembrane 9 superfamily member 2 OS=Homo sapiens OX=9606 GN=TM9SF2 PE=1 SV=1 4.54 2433.1 - 8.38E+06 - - - 2.2054 - 2.783 0.419 - 471.5 1 2 0 0.0032 12 0 0 0 9.21E+07 8.53E+07 - - - 6.0476 1 221125_WJC_METTL3_EV_vs_WT_F06.13744.13744.3 3.26E-08 15/60 K.TGVAVNK[136.11]PAEFTVDAK[136.11].H "sp|P21333|FLNA_HUMAN,tr|A0A7P0NMY4|A0A7P0NMY4_HUMAN,tr|Q60FE5|Q60FE5_HUMAN" 3 1661.8959 1.11 82995 13744 3 1661.89701 554.9726 Filamin-A OS=Homo sapiens OX=9606 GN=FLNA PE=1 SV=4 5.73 2433.2 - 4.76E+06 - - - 0.6462 - 3.227 0.525 - 253.9 1 2 0 0.0011 16 0 0 0 9.42E+07 8.47E+07 - - - 7.399 1 221125_WJC_METTL3_EV_vs_WT_F06.13745.13745.3 5.41E-07 14/60 K.TGVAVNKPAEFTVDAK.H "sp|P21333|FLNA_HUMAN,tr|A0A7P0NMY4|A0A7P0NMY4_HUMAN,tr|Q60FE5|Q60FE5_HUMAN" 3 1645.8675 1.12 82996 13745 3 1645.869382 549.6298 Filamin-A OS=Homo sapiens OX=9606 GN=FLNA PE=1 SV=4 5.73 2433.2 - 4.45E+06 - - - 1.1216 - 3.15 0.579 - 218.3 1 2 0 0.0018 16 0 0 0 9.45E+07 8.47E+07 - - - 7.9388 0.9801 221125_WJC_METTL3_EV_vs_WT_F06.13746.13746.3 0.00246 Sep-40 A.LYFHIGETEKK.C sp|Q9BVK6|TMED9_HUMAN 1 1363.7136 1.12 82997 13746 3 1363.714602 455.5785 Transmembrane emp24 domain-containing protein 9 OS=Homo sapiens OX=9606 GN=TMED9 PE=1 SV=2 6.76 2433.2 - 3.46E+06 - - - 0.7333 - 1.935 0.375 - 106.6 1 1 0 0.001 11 0 0 0 4.81E+07 4.31E+07 - - - 4.5959 0.8839 221125_WJC_METTL3_EV_vs_WT_F06.13747.13747.3 0.0252 Aug-40 A.LYFHIGETEK[136.11]K[136.11].C sp|Q9BVK6|TMED9_HUMAN 1 1379.742 1.36 82998 13747 3 1379.74271 460.9213 Transmembrane emp24 domain-containing protein 9 OS=Homo sapiens OX=9606 GN=TMED9 PE=1 SV=2 6.76 2433.3 - 2.58E+06 - - - 0.5131 - 1.601 0.294 - 89.2 1 1 0 0.0007 11 0 0 0 4.77E+07 3.50E+07 - - - 3.1546 0.9921 221125_WJC_METTL3_EV_vs_WT_F06.13748.13748.3 0.000187 13/44 N.REEEWDPEYTPK.S "sp|Q9Y2W1|TR150_HUMAN,tr|A0A3B3ITZ9|A0A3B3ITZ9_HUMAN" 2 1577.6998 3.19 82999 13748 3 1577.702592 526.9072 Thyroid hormone receptor-associated protein 3 OS=Homo sapiens OX=9606 GN=THRAP3 PE=1 SV=2 4.25 2433.4 - 2.07E+06 - - - 1.7684 - 2.24 0.47 - 339 1 1 0 0.0028 12 0 0 0 2.07E+07 6.49E+06 - - - 6.0147 0.9181 221125_WJC_METTL3_EV_vs_WT_F06.13749.13749.3 0.389 Sep-48 K.LVNNGEKLEFLHK.T sp|Q15393|SF3B3_HUMAN 1 1539.8409 0.96 83000 13749 3 1539.8432 514.2876 Splicing factor 3B subunit 3 OS=Homo sapiens OX=9606 GN=SF3B3 PE=1 SV=4 6.76 2433.4 - 1.12E+06 - - - 1.4755 - 1.558 0.169 - 54.2 1 2 1 0.0023 13 0 0 0 6.75E+06 7.04E+06 - - - 1.6257 1 221125_WJC_METTL3_EV_vs_WT_F06.13750.13750.2 0.000144 13/26 K.GYVWNGGSNPQANR.Q sp|Q9BRS2|RIOK1_HUMAN 1 1518.6964 1.41 83001 13750 2 1518.696738 760.3555 Serine\threonine-protein kinase RIO1 OS=Homo sapiens OX=9606 GN=RIOK1 PE=1 SV=2 8.75 2433.6 - 916800 - - - 0.2298 - 2.971 0.603 - 710 1 2 0 0.0003 14 0 0 0 1.63E+07 1.15E+07 - - - 6.2272 1 221125_WJC_METTL3_EV_vs_WT_F06.13751.13751.2 7.87E-08 17/30 Y.GSGLGVGGGFSSSSGR.A "sp|P04259|K2C6B_HUMAN,sp|P02538|K2C6A_HUMAN" 2 1367.643 999 83002 13751 2 1367.643534 684.8288 "Keratin, type II cytoskeletal 6B OS=Homo sapiens OX=9606 GN=KRT6B PE=1 SV=5" 9.75 2433.7 - 799544 - - - 0.4226 - 2.789 0.607 - 655.4 1 1 0 0.0006 16 0 0 0 1.07E+07 0.00E+00 - - - 6.0458 0.9996 221125_WJC_METTL3_EV_vs_WT_F06.13753.13753.2 0.000303 22-Oct R.GQNQPVLNITNK[136.11].Q "sp|P31327|CPSM_HUMAN,tr|Q5R211|Q5R211_HUMAN" 2 1332.7241 4.09 83004 13753 2 1332.721272 667.3693 "Carbamoyl-phosphate synthase [ammonia], mitochondrial OS=Homo sapiens OX=9606 GN=CPS1 PE=1 SV=2" 8.75 2434 - 481830 - - - -2.1317 - 1.921 0.475 - 372.4 1 2 0 -0.0028 12 0 0 0 1.96E+07 4.80E+06 - - - 4.2662 0.8024 221125_WJC_METTL3_EV_vs_WT_F06.13755.13755.3 0.0372 Jul-56 K.K[136.11]AEAGAGSATEFQFR[166.11].G "sp|Q9NQ39|RS10L_HUMAN,sp|P46783|RS10_HUMAN" 2 1586.7808 0.42 83006 13755 3 1586.784831 529.9342 Putative 40S ribosomal protein S10-like OS=Homo sapiens OX=9606 GN=RPS10P5 PE=5 SV=1 6.14 2434.1 - 429013 - - - 2.5467 - 1.593 0.086 - 63.3 2 2 0 0.004 15 0 0 0 6.84E+05 1.61E+06 - - - 0.5733 1 221125_WJC_METTL3_EV_vs_WT_F06.13757.13757.3 1.31E-10 18/80 R.AVYEDRPPGSVVPTSAAEASR.A sp|Q9H1Z4|WDR13_HUMAN 1 2158.0655 2.39 83008 13757 3 2158.067699 720.3624 WD repeat-containing protein 13 OS=Homo sapiens OX=9606 GN=WDR13 PE=1 SV=2 4.68 2434.4 - 336554 - - - 1.037 - 3.421 0.603 - 256.8 1 2 0 0.0022 21 0 0 0 2.93E+07 1.22E+07 - - - 8.2109 0.9997 221125_WJC_METTL3_EV_vs_WT_F06.13758.13758.2 3.99E-09 13/30 K.TGVAVNK[136.11]PAEFTVDAK[136.11].H "sp|P21333|FLNA_HUMAN,tr|A0A7P0NMY4|A0A7P0NMY4_HUMAN,tr|Q60FE5|Q60FE5_HUMAN" 3 1661.8959 1.25 83009 13758 2 1661.899014 831.9552 Filamin-A OS=Homo sapiens OX=9606 GN=FLNA PE=1 SV=4 5.73 2434.5 - 285697 - - - 1.8521 - 2.778 0.449 - 512.6 1 2 0 0.0031 16 0 0 0 5.32E+06 4.26E+06 - - - 4.8683 1 221125_WJC_METTL3_EV_vs_WT_F06.13759.13759.2 3.55E-08 14/30 K.TGVAVNKPAEFTVDAK.H "sp|P21333|FLNA_HUMAN,tr|A0A7P0NMY4|A0A7P0NMY4_HUMAN,tr|Q60FE5|Q60FE5_HUMAN" 3 1645.8675 1.25 83010 13759 2 1645.864105 823.941 Filamin-A OS=Homo sapiens OX=9606 GN=FLNA PE=1 SV=4 5.73 2434.7 - 236351 - - - -2.0846 - 3.088 0.578 - 641 1 2 0 -0.0034 16 0 0 0 5.32E+06 4.26E+06 - - - 6.0811 1 221125_WJC_METTL3_EV_vs_WT_F06.13762.13762.3 4.68E-07 14/48 R.KASGPPVSELITK.A "sp|P10412|H14_HUMAN,sp|P16403|H12_HUMAN,sp|P16402|H13_HUMAN" 3 1325.7555 0.81 83012 13762 3 1325.756607 442.9258 Histone H1.4 OS=Homo sapiens OX=9606 GN=H1-4 PE=1 SV=2 8.59 2435 - 1.26E+07 - - - 0.8599 - 2.878 0.594 - 281.5 1 2 0 0.0011 13 0 0 0 5.60E+08 6.94E+08 - - - 8.0283 1 221125_WJC_METTL3_EV_vs_WT_F06.13764.13764.3 1.61E-06 15/56 K.AVDQHNAEAQDIFGK.N "sp|P52732|KIF11_HUMAN,tr|A0A7I2YQY4|A0A7I2YQY4_HUMAN,tr|A0A7I2V3A9|A0A7I2V3A9_HUMAN" 3 1641.7747 5.1 83013 13764 3 1641.77674 548.2655 Kinesin-like protein KIF11 OS=Homo sapiens OX=9606 GN=KIF11 PE=1 SV=2 4.54 2435.2 - 1.22E+07 - - - 1.2438 - 3.09 0.621 - 223.3 1 2 0 0.002 15 0 0 0 1.66E+09 3.25E+08 - - - 8.4068 0.9999 221125_WJC_METTL3_EV_vs_WT_F06.13765.13765.3 1.90E-08 18/60 K.VTVAGLAGKDPVQC[160.03]SR.D "sp|Q99497|PARK7_HUMAN,tr|K7ELW0|K7ELW0_HUMAN" 2 1656.8617 2.27 83014 13765 3 1656.864396 553.2945 Parkinson disease protein 7 OS=Homo sapiens OX=9606 GN=PARK7 PE=1 SV=2 8.19 2435.3 - 9.94E+06 - - - 1.603 - 3.203 0.565 - 370.6 1 2 1 0.0027 16 0 0 0 1.22E+09 5.39E+08 - - - 7.8253 0.9999 221125_WJC_METTL3_EV_vs_WT_F06.13767.13767.3 1.11E-06 Dec-56 K.KAEAGAGSATEFQFR.G "sp|Q9NQ39|RS10L_HUMAN,sp|P46783|RS10_HUMAN" 2 1568.7583 1.28 83016 13767 3 1568.761055 523.9267 Putative 40S ribosomal protein S10-like OS=Homo sapiens OX=9606 GN=RPS10P5 PE=5 SV=1 6.14 2435.4 - 1.17E+06 - - - 1.7434 - 2.68 0.402 - 236.3 1 2 0 0.0027 15 0 0 0 4.69E+09 3.68E+09 - - - 5.5935 0.9992 221125_WJC_METTL3_EV_vs_WT_F06.13768.13768.4 0.018 Dec-78 R.FGLESHAHTIQIC[160.03]K[136.11].L "sp|Q8NE71|ABCF1_HUMAN,tr|A0A0G2JIC2|A0A0G2JIC2_HUMAN,tr|Q5STZ8|Q5STZ8_HUMAN,tr|H0YGW7|H0YGW7_HUMAN" 4 1647.8283 0.84 83017 13768 4 1647.829734 412.9643 ATP-binding cassette sub-family F member 1 OS=Homo sapiens OX=9606 GN=ABCF1 PE=1 SV=2 6.91 2435.5 - 975523 - - - 0.8939 - 1.83 0.31 - 48.1 1 2 0 0.0015 14 0 0 0 1.70E+07 2.01E+07 - - - 2.1438 0.9517 221125_WJC_METTL3_EV_vs_WT_F06.13774.13774.3 0.00554 Nov-64 R.TERPVNSAALSPNYDHV.V "sp|Q13347|EIF3I_HUMAN,tr|A0A7I2YQT9|A0A7I2YQT9_HUMAN,tr|A0A7I2V613|A0A7I2V613_HUMAN,tr|A0A7I2V3N2|A0A7I2V3N2_HUMAN,tr|A0A7I2YQU2|A0A7I2YQU2_HUMAN,tr|A0A7I2YQI6|A0A7I2YQI6_HUMAN,tr|A0A7I2YQF8|A0A7I2YQF8_HUMAN,tr|Q5TFK1|Q5TFK1_HUMAN,tr|A0A7I2V3U3|A0A7I2V3U3_HUMAN,tr|A0A7I2V607|A0A7I2V607_HUMAN,tr|A0A7I2V640|A0A7I2V640_HUMAN,tr|A0A7P0MRT9|A0A7P0MRT9_HUMAN,tr|A0A7I2V3K6|A0A7I2V3K6_HUMAN,tr|A0A7I2V4S8|A0A7I2V4S8_HUMAN,tr|A0A7I2V5V8|A0A7I2V5V8_HUMAN,tr|A0A7I2V2M3|A0A7I2V2M3_HUMAN,tr|A0A7I2V4C2|A0A7I2V4C2_HUMAN,tr|A0A7I2YQP9|A0A7I2YQP9_HUMAN,tr|A0A7I2YQI2|A0A7I2YQI2_HUMAN,tr|A0A7I2YQC8|A0A7I2YQC8_HUMAN,tr|A0A7I2V685|A0A7I2V685_HUMAN" 21 1868.9017 17.52 83023 13774 3 1868.907216 623.9745 Eukaryotic translation initiation factor 3 subunit I OS=Homo sapiens OX=9606 GN=EIF3I PE=1 SV=1 5.29 2436.3 - 335197 - - - 2.9568 - 2.225 0.394 - 89.1 1 1 0 0.0055 17 0 0 0 2.31E+06 1.32E+05 - - - 4.9516 0.9997 221125_WJC_METTL3_EV_vs_WT_F06.13775.13775.2 2.13E-06 20-Dec R.ESVDHLTIPSR[166.11].C "sp|P41252|SYIC_HUMAN,tr|A0A804HL54|A0A804HL54_HUMAN,tr|A0A804HKU1|A0A804HKU1_HUMAN,tr|A0A804HK69|A0A804HK69_HUMAN,tr|A0A804HIV9|A0A804HIV9_HUMAN,tr|A0A804HJN6|A0A804HJN6_HUMAN,tr|A0A804HHW9|A0A804HHW9_HUMAN,tr|A0A0A0MSX9|A0A0A0MSX9_HUMAN,tr|J3KR24|J3KR24_HUMAN,tr|A0A804HJ36|A0A804HJ36_HUMAN" 10 1262.6494 1.07 83024 13775 2 1262.651596 632.332 "Isoleucine--tRNA ligase, cytoplasmic OS=Homo sapiens OX=9606 GN=IARS1 PE=1 SV=2" 5.32 2436.4 - 318245 - - - 1.7115 - 2.414 0.383 - 600.4 1 2 0 0.0022 11 0 0 0 9.29E+06 8.67E+06 - - - 4.2532 1 221125_WJC_METTL3_EV_vs_WT_F06.13776.13776.2 2.09E-08 Dec-32 R.TDTAADGETTATEELEK[136.11].T "tr|A0A0J9YWE1|A0A0J9YWE1_HUMAN,tr|A8K968|A8K968_HUMAN,tr|A0A0J9YY18|A0A0J9YY18_HUMAN,tr|A0A0J9YWS4|A0A0J9YWS4_HUMAN,tr|A0A0J9YWN0|A0A0J9YWN0_HUMAN" 5 1788.7992 1.23 83025 13776 2 1788.798879 895.4069 Band 4.1-like protein 3 (Fragment) OS=Homo sapiens OX=9606 GN=EPB41L3 PE=1 SV=1 3.77 2436.5 - 269934 - - - -0.2063 - 2.688 0.676 - 298.9 1 2 0 -0.0004 17 0 0 0 2.99E+06 2.42E+06 - - - 6.4648 0.9988 221125_WJC_METTL3_EV_vs_WT_F06.13777.13777.2 1.16E-06 14/30 K.VTVAGLAGK[136.11]DPVQC[160.03]SR[166.11].D "sp|Q99497|PARK7_HUMAN,tr|K7ELW0|K7ELW0_HUMAN" 2 1674.8842 2.75 83026 13777 2 1674.883845 838.4494 Parkinson disease protein 7 OS=Homo sapiens OX=9606 GN=PARK7 PE=1 SV=2 8.19 2436.6 - 198372 - - - -0.2179 - 2.57 0.51 - 375.3 1 2 1 -0.0004 16 0 0 0 5.83E+07 2.12E+07 - - - 5.1284 0.9998 221125_WJC_METTL3_EV_vs_WT_F06.13781.13781.2 7.38E-06 14/24 R.K[136.11]ASGPPVSELITK[136.11].A "sp|P10412|H14_HUMAN,sp|P16403|H12_HUMAN,sp|P16402|H13_HUMAN" 3 1341.7839 0.81 83029 13781 2 1341.785679 671.8992 Histone H1.4 OS=Homo sapiens OX=9606 GN=H1-4 PE=1 SV=2 8.59 2437.3 - 1.14E+06 - - - 1.3504 - 2.849 0.448 - 578.8 1 2 0 0.0018 13 0 0 0 1.11E+08 1.36E+08 - - - 5.0364 0.9998 221125_WJC_METTL3_EV_vs_WT_F06.13783.13783.3 0.000637 Nov-44 K.LEQLHIMQEQQK.S "sp|Q6P3W7|SCYL2_HUMAN,tr|F8VSC5|F8VSC5_HUMAN,tr|A0A0U1RQQ9|A0A0U1RQQ9_HUMAN" 3 1523.7766 1.85 83030 13783 3 1523.779402 508.9328 SCY1-like protein 2 OS=Homo sapiens OX=9606 GN=SCYL2 PE=1 SV=1 5.4 2437.5 - 4.48E+06 - - - 1.8303 - 2.367 0.358 - 181.9 1 2 0 0.0028 12 0 0 0 1.23E+08 6.63E+07 - - - 4.9189 1 221125_WJC_METTL3_EV_vs_WT_F06.13784.13784.2 2.42E-09 21/28 K.AVDQHNAEAQDIFGK.N "sp|P52732|KIF11_HUMAN,tr|A0A7I2YQY4|A0A7I2YQY4_HUMAN,tr|A0A7I2V3A9|A0A7I2V3A9_HUMAN" 3 1641.7747 4.08 83031 13784 2 1641.777593 821.8946 Kinesin-like protein KIF11 OS=Homo sapiens OX=9606 GN=KIF11 PE=1 SV=2 4.54 2437.6 - 2.43E+06 - - - 1.7633 - 4.005 0.653 - 1758.7 1 2 0 0.0029 15 0 0 0 1.29E+08 3.15E+07 - - - 7.2745 0.9957 221125_WJC_METTL3_EV_vs_WT_F06.13785.13785.3 0.0662 Dec-44 K.LEQLHIMQEQQK[136.11].S "sp|Q6P3W7|SCYL2_HUMAN,tr|F8VSC5|F8VSC5_HUMAN,tr|A0A0U1RQQ9|A0A0U1RQQ9_HUMAN" 3 1531.7908 3.53 83032 13785 3 1531.7934 511.6042 SCY1-like protein 2 OS=Homo sapiens OX=9606 GN=SCYL2 PE=1 SV=1 5.4 2437.6 - 2.72E+06 - - - 1.6889 - 1.915 0.206 - 135.7 1 2 0 0.0026 12 0 0 0 1.09E+08 3.10E+07 - - - 2.6369 1 221125_WJC_METTL3_EV_vs_WT_F06.13786.13786.3 0.000644 17/52 R.FAQHGTFEYEYSQR[166.11].W "sp|P23246|SFPQ_HUMAN,tr|H0Y9K7|H0Y9K7_HUMAN" 2 1771.783 0.81 83033 13786 3 1771.783819 591.6016 "Splicing factor, proline- and glutamine-rich OS=Homo sapiens OX=9606 GN=SFPQ PE=1 SV=2" 5.4 2437.7 - 1.85E+06 - - - 0.4803 - 2.575 0.508 - 326.6 1 2 0 0.0008 14 0 0 0 3.67E+08 4.53E+08 - - - 6.7171 1 221125_WJC_METTL3_EV_vs_WT_F06.13788.13788.3 1.37E-09 15/52 R.FAQHGTFEYEYSQR.W "sp|P23246|SFPQ_HUMAN,tr|H0Y9K7|H0Y9K7_HUMAN" 2 1761.7747 0.81 83035 13788 3 1761.777772 588.2655 "Splicing factor, proline- and glutamine-rich OS=Homo sapiens OX=9606 GN=SFPQ PE=1 SV=2" 5.4 2437.8 - 1.34E+06 - - - 1.7448 - 2.826 0.622 - 272.2 1 2 0 0.0031 14 0 0 0 3.66E+08 4.52E+08 - - - 8.2346 0.9998 221125_WJC_METTL3_EV_vs_WT_F06.13789.13789.2 2.21E-06 26-Dec K.GYVWNGGSNPQANR[166.11].Q sp|Q9BRS2|RIOK1_HUMAN 1 1528.7047 1.41 83036 13789 2 1528.705459 765.3596 Serine\threonine-protein kinase RIO1 OS=Homo sapiens OX=9606 GN=RIOK1 PE=1 SV=2 8.75 2437.9 - 888154 - - - 0.5233 - 2.401 0.433 - 579.5 1 2 0 0.0008 14 0 0 0 1.63E+07 1.15E+07 - - - 4.4369 1 221125_WJC_METTL3_EV_vs_WT_F06.13792.13792.2 5.65E-05 17/30 K.VTVAGLAGKDPVQC[160.03]SR.D "sp|Q99497|PARK7_HUMAN,tr|K7ELW0|K7ELW0_HUMAN" 2 1656.8617 2.75 83039 13792 2 1656.865195 829.4381 Parkinson disease protein 7 OS=Homo sapiens OX=9606 GN=PARK7 PE=1 SV=2 8.19 2438.3 - 729153 - - - 2.0853 - 3.154 0.558 - 518.6 1 2 1 0.0035 16 0 0 0 5.83E+07 2.12E+07 - - - 5.9854 0.9967 221125_WJC_METTL3_EV_vs_WT_F06.13793.13793.3 0.00827 Sep-64 R.LSQVSDSVSGQTVVDPK[136.11].G sp|O94906|PRP6_HUMAN 1 1752.8985 3.33 83040 13793 3 1752.902239 585.3068 Pre-mRNA-processing factor 6 OS=Homo sapiens OX=9606 GN=PRPF6 PE=1 SV=1 4.21 2438.4 - 703073 - - - 2.1279 - 1.691 0.281 - 68.2 1 2 0 0.0037 17 0 0 0 3.81E+07 1.15E+07 - - - 2.999 0.9996 221125_WJC_METTL3_EV_vs_WT_F06.13794.13794.3 3.38E-05 Dec-44 K.GGHSSSLFGNIK.G sp|P33908|MA1A1_HUMAN 1 1202.6044 1.25 83041 13794 3 1202.607038 401.8754 "Mannosyl-oligosaccharide 1,2-alpha-mannosidase IA OS=Homo sapiens OX=9606 GN=MAN1A1 PE=1 SV=3" 8.76 2438.5 - 582072 - - - 2.2052 - 1.749 0.419 - 157.2 1 2 0 0.0027 12 0 0 0 5.61E+07 4.48E+07 - - - 4.7603 0.9987 221125_WJC_METTL3_EV_vs_WT_F06.13795.13795.3 2.40E-05 15/56 R.SRVGIQQGLLSQSTR.T "sp|Q9BY77|PDIP3_HUMAN,tr|F6VRR5|F6VRR5_HUMAN,tr|F8WCX5|F8WCX5_HUMAN,tr|Q6R954|Q6R954_HUMAN,tr|Q8WUT1|Q8WUT1_HUMAN,tr|F8WEE2|F8WEE2_HUMAN" 6 1628.8958 2.95 83042 13795 3 1628.902155 543.9725 Polymerase delta-interacting protein 3 OS=Homo sapiens OX=9606 GN=POLDIP3 PE=1 SV=2 12 2438.7 - 564896 - - - 3.891 - 3.089 0.427 - 372.6 1 2 1 0.0063 15 0 0 0 1.02E+07 3.46E+06 - - - 6.2418 0.9999 221125_WJC_METTL3_EV_vs_WT_F06.13798.13798.2 1.21E-08 18/28 R.SPNQNVQQAAAGALR.N sp|Q13835|PKP1_HUMAN 1 1523.7805 123.61 83045 13798 2 1523.780216 762.8975 Plakophilin-1 OS=Homo sapiens OX=9606 GN=PKP1 PE=1 SV=2 9.47 2439 - 484836 - - - -0.1555 - 3.591 0.314 - 1284.2 1 2 0 -0.0002 15 0 0 0 1.79E+08 1.44E+06 - - - 4.5032 1 221125_WJC_METTL3_EV_vs_WT_F06.13800.13800.2 3.12E-12 19/24 V.DQHNAEAQDIFGK.N "sp|P52732|KIF11_HUMAN,tr|A0A7I2YQY4|A0A7I2YQY4_HUMAN,tr|A0A7I2V3A9|A0A7I2V3A9_HUMAN" 3 1471.6692 21.54 83047 13800 2 1471.667523 736.8419 Kinesin-like protein KIF11 OS=Homo sapiens OX=9606 GN=KIF11 PE=1 SV=2 4.54 2439.3 - 311993 - - - -1.1198 - 3.6 0.656 - 1301.1 1 1 0 -0.0016 13 0 0 0 1.30E+07 6.03E+05 - - - 7.1733 0.9986 221125_WJC_METTL3_EV_vs_WT_F06.13802.13802.3 0.0248 Oct-40 R.ESVDHLTIPSR.C "sp|P41252|SYIC_HUMAN,tr|A0A804HL54|A0A804HL54_HUMAN,tr|A0A804HKU1|A0A804HKU1_HUMAN,tr|A0A804HK69|A0A804HK69_HUMAN,tr|A0A804HIV9|A0A804HIV9_HUMAN,tr|A0A804HJN6|A0A804HJN6_HUMAN,tr|A0A804HHW9|A0A804HHW9_HUMAN,tr|A0A0A0MSX9|A0A0A0MSX9_HUMAN,tr|J3KR24|J3KR24_HUMAN,tr|A0A804HJ36|A0A804HJ36_HUMAN" 10 1252.6412 0.81 83048 13802 3 1252.642211 418.5543 "Isoleucine--tRNA ligase, cytoplasmic OS=Homo sapiens OX=9606 GN=IARS1 PE=1 SV=2" 5.32 2439.5 - 8.56E+06 - - - 0.835 - 2.04 0.226 - 140 1 2 0 0.001 11 0 0 0 1.01E+08 1.24E+08 - - - 3.0848 1 221125_WJC_METTL3_EV_vs_WT_F06.13804.13804.2 2.68E-10 20/28 K.KAEAGAGSATEFQFR.G "sp|Q9NQ39|RS10L_HUMAN,sp|P46783|RS10_HUMAN" 2 1568.7583 1.26 83049 13804 2 1568.758182 785.3864 Putative 40S ribosomal protein S10-like OS=Homo sapiens OX=9606 GN=RPS10P5 PE=5 SV=1 6.14 2439.7 - 2.62E+06 - - - -0.088 - 4.271 0.577 - 1458.2 1 2 0 -0.0001 15 0 0 0 4.18E+08 3.32E+08 - - - 6.8721 1 221125_WJC_METTL3_EV_vs_WT_F06.13805.13805.2 5.38E-08 18/28 K.K[136.11]AEAGAGSATEFQFR[166.11].G "sp|Q9NQ39|RS10L_HUMAN,sp|P46783|RS10_HUMAN" 2 1586.7808 1.26 83050 13805 2 1586.779377 794.3977 Putative 40S ribosomal protein S10-like OS=Homo sapiens OX=9606 GN=RPS10P5 PE=5 SV=1 6.14 2439.8 - 2.29E+06 - - - -0.8905 - 3.953 0.613 - 1061.9 1 2 0 -0.0014 15 0 0 0 4.17E+08 3.31E+08 - - - 6.9474 1 221125_WJC_METTL3_EV_vs_WT_F06.13808.13808.2 4.56E-08 13/20 K.HNMDIGTWDNK.G "sp|Q9Y5A9|YTHD2_HUMAN,sp|Q9BYJ9|YTHD1_HUMAN" 2 1329.5772 1.42 83053 13808 2 1329.577262 665.7959 YTH domain-containing family protein 2 OS=Homo sapiens OX=9606 GN=YTHDF2 PE=1 SV=2 5.21 2440.1 - 1.39E+06 - - - 0.0579 - 2.99 0.66 - 395.9 1 2 0 0.0001 11 0 0 0 6.95E+07 4.91E+07 - - - 6.8787 1 221125_WJC_METTL3_EV_vs_WT_F06.13809.13809.2 1.13E-07 15/20 K.HNMDIGTWDNK[136.11].G "sp|Q9Y5A9|YTHD2_HUMAN,sp|Q9BYJ9|YTHD1_HUMAN" 2 1337.5914 1.42 83054 13809 2 1337.590058 669.803 YTH domain-containing family protein 2 OS=Homo sapiens OX=9606 GN=YTHDF2 PE=1 SV=2 5.21 2440.2 - 1.00E+06 - - - -0.9921 - 3.274 0.677 - 524 1 2 0 -0.0013 11 0 0 0 6.95E+07 4.91E+07 - - - 7.2493 0.9995 221125_WJC_METTL3_EV_vs_WT_F06.13810.13810.3 0.00187 15/64 R.QLPAQPPEHAVDGEGFK[136.11].N "sp|Q14151|SAFB2_HUMAN,tr|K7ERX3|K7ERX3_HUMAN,tr|K7EQU4|K7EQU4_HUMAN" 3 1826.9043 0.81 83055 13810 3 1826.900157 609.9754 Scaffold attachment factor B2 OS=Homo sapiens OX=9606 GN=SAFB2 PE=1 SV=1 4.65 2440.3 - 974625 - - - -2.2475 - 2.528 0.316 - 237.6 1 2 0 -0.0041 17 0 0 0 1.65E+07 2.05E+07 - - - 4.4049 0.9995 221125_WJC_METTL3_EV_vs_WT_F06.13811.13811.3 0.00193 16/64 R.QLPAQPPEHAVDGEGFK.N "sp|Q14151|SAFB2_HUMAN,tr|K7ERX3|K7ERX3_HUMAN,tr|K7EQU4|K7EQU4_HUMAN" 3 1818.8901 1.04 83056 13811 3 1818.892452 607.304 Scaffold attachment factor B2 OS=Homo sapiens OX=9606 GN=SAFB2 PE=1 SV=1 4.65 2440.5 - 915437 - - - 1.3134 - 2.154 0.322 - 55.3 1 2 0 0.0024 17 0 0 0 5.85E+06 5.60E+06 - - - 4.0678 1 221125_WJC_METTL3_EV_vs_WT_F06.13812.13812.3 1.63E-07 21/80 R.AVYEDR[166.11]PPGSVVPTSAAEASR[166.11].A sp|Q9H1Z4|WDR13_HUMAN 1 2178.082 2.29 83057 13812 3 2178.082122 727.0346 WD repeat-containing protein 13 OS=Homo sapiens OX=9606 GN=WDR13 PE=1 SV=2 4.68 2440.6 - 654875 - - - 0.0556 - 3.18 0.493 - 204.3 1 2 0 0.0001 21 0 0 0 2.80E+07 1.22E+07 - - - 6.81 1 221125_WJC_METTL3_EV_vs_WT_F06.13818.13818.3 1.47E-07 Nov-40 K.HNMDIGTWDNK.G "sp|Q9Y5A9|YTHD2_HUMAN,sp|Q9BYJ9|YTHD1_HUMAN" 2 1329.5772 1.43 83062 13818 3 1329.575766 444.1997 YTH domain-containing family protein 2 OS=Homo sapiens OX=9606 GN=YTHDF2 PE=1 SV=2 5.21 2441.3 - 4.88E+06 - - - -1.0673 - 2.317 0.625 - 197.3 1 2 0 -0.0014 11 0 0 0 1.15E+08 8.06E+07 - - - 7.8948 1 221125_WJC_METTL3_EV_vs_WT_F06.13819.13819.3 2.39E-05 13/40 K.HNMDIGTWDNK[136.11].G "sp|Q9Y5A9|YTHD2_HUMAN,sp|Q9BYJ9|YTHD1_HUMAN" 2 1337.5914 1.43 83063 13819 3 1337.590541 446.8711 YTH domain-containing family protein 2 OS=Homo sapiens OX=9606 GN=YTHDF2 PE=1 SV=2 5.21 2441.3 - 3.57E+06 - - - -0.631 - 2.249 0.537 - 301.4 1 2 0 -0.0008 11 0 0 0 1.15E+08 8.06E+07 - - - 6.8292 0.9923 221125_WJC_METTL3_EV_vs_WT_F06.13820.13820.3 0.00762 Dec-36 L.DTYNC[160.03]DLHFK[136.11].L "sp|Q00839|HNRPU_HUMAN,sp|Q9BUJ2|HNRL1_HUMAN,tr|Q5RI18|Q5RI18_HUMAN,tr|M0R0K8|M0R0K8_HUMAN,tr|A0A1W2PP35|A0A1W2PP35_HUMAN,tr|A0A1W2PPS1|A0A1W2PPS1_HUMAN,tr|M0QYZ0|M0QYZ0_HUMAN,tr|A0A0A0MRA5|A0A0A0MRA5_HUMAN,tr|M0R3F1|M0R3F1_HUMAN,tr|B7Z4B8|B7Z4B8_HUMAN,tr|A0A1W2PRI6|A0A1W2PRI6_HUMAN,tr|M0QYI8|M0QYI8_HUMAN,tr|M0QYM5|M0QYM5_HUMAN" 13 1319.5696 1.13 83064 13820 3 1319.571264 440.8638 Heterogeneous nuclear ribonucleoprotein U OS=Homo sapiens OX=9606 GN=HNRNPU PE=1 SV=6 5.21 2441.4 - 3.07E+06 - - - 1.2709 - 2.028 0.461 - 170.1 1 1 0 0.0017 10 0 0 0 5.28E+07 4.68E+07 - - - 5.7441 1 221125_WJC_METTL3_EV_vs_WT_F06.13825.13825.2 1.09E-10 18/26 R.FAQHGTFEYEYSQR[166.11].W "sp|P23246|SFPQ_HUMAN,tr|H0Y9K7|H0Y9K7_HUMAN" 2 1771.783 0.7 83069 13825 2 1771.778772 886.8988 "Splicing factor, proline- and glutamine-rich OS=Homo sapiens OX=9606 GN=SFPQ PE=1 SV=2" 5.4 2442 - 613416 - - - -2.3682 - 3.313 0.562 - 1062.7 1 2 0 -0.0042 14 0 0 0 1.81E+07 2.61E+07 - - - 6.1966 0.9999 221125_WJC_METTL3_EV_vs_WT_F06.13831.13831.3 1.08E-05 Nov-40 K.SEEEFIHINNK[136.11].L "sp|Q15046|SYK_HUMAN,tr|H3BVA8|H3BVA8_HUMAN,tr|J3KRL2|J3KRL2_HUMAN" 3 1366.6608 0.89 83073 13831 3 1366.659032 456.5609 Lysine--tRNA ligase OS=Homo sapiens OX=9606 GN=KARS1 PE=1 SV=3 4.75 2442.6 - 3.12E+06 - - - -1.3259 - 2.061 0.439 - 146.6 1 2 0 -0.0018 11 0 0 0 9.48E+07 1.07E+08 - - - 5.4884 0.9999 221125_WJC_METTL3_EV_vs_WT_F06.13832.13832.3 0.00036 15/44 K.KVEAQLQELQVK.F sp|P35579|MYH9_HUMAN 1 1411.8035 0.91 83074 13832 3 1411.804583 471.6084 Myosin-9 OS=Homo sapiens OX=9606 GN=MYH9 PE=1 SV=4 6.14 2442.6 - 2.59E+06 - - - 0.782 - 2.772 0.396 - 507.1 1 2 0 0.0011 12 0 0 0 7.55E+07 8.29E+07 - - - 5.7808 1 221125_WJC_METTL3_EV_vs_WT_F06.13834.13834.2 2.42E-09 15/28 R.GGGGNFGPGPGSNFR.G "sp|P22626|ROA2_HUMAN,tr|A0A024RA28|A0A024RA28_HUMAN,tr|A0A7I2V4N1|A0A7I2V4N1_HUMAN,tr|A0A7I2V4I6|A0A7I2V4I6_HUMAN,tr|A0A7I2V4S4|A0A7I2V4S4_HUMAN,tr|A0A7I2V323|A0A7I2V323_HUMAN,tr|A0A7I2V3P1|A0A7I2V3P1_HUMAN,tr|A0A7I2V3P7|A0A7I2V3P7_HUMAN" 8 1376.6222 1.42 83076 13834 2 1376.619969 689.3184 Heterogeneous nuclear ribonucleoproteins A2\B1 OS=Homo sapiens OX=9606 GN=HNRNPA2B1 PE=1 SV=2 9.75 2442.8 - 1.02E+06 - - - -1.5923 - 2.347 0.622 - 625.1 1 2 0 -0.0022 15 0 0 0 1.42E+08 9.97E+07 - - - 5.7319 0.9932 221125_WJC_METTL3_EV_vs_WT_F06.13838.13838.3 0.00195 16/64 R.LGSRPQPAEAYAEAVQR.L sp|Q5T447|HECD3_HUMAN 1 1841.9384 1.84 83080 13838 3 1841.940688 614.9867 E3 ubiquitin-protein ligase HECTD3 OS=Homo sapiens OX=9606 GN=HECTD3 PE=1 SV=1 6.14 2443.3 - 345333 - - - 1.2367 - 1.965 0.173 - 215 1 2 0 0.0023 17 0 0 0 4.36E+06 2.37E+06 - - - 2.1746 0.9999 221125_WJC_METTL3_EV_vs_WT_F06.13843.13843.3 0.00123 Nov-40 K.SEEEFIHINNK.L "sp|Q15046|SYK_HUMAN,tr|H3BVA8|H3BVA8_HUMAN,tr|J3KRL2|J3KRL2_HUMAN" 3 1358.6466 0.89 83083 13843 3 1358.645592 453.8895 Lysine--tRNA ligase OS=Homo sapiens OX=9606 GN=KARS1 PE=1 SV=3 4.75 2443.9 - 4.76E+06 - - - -0.7743 - 1.775 0.422 - 159 1 2 0 -0.0011 11 0 0 0 9.49E+07 1.07E+08 - - - 4.8747 0.9999 221125_WJC_METTL3_EV_vs_WT_F06.13844.13844.2 3.63E-07 19/22 K.K[136.11]VEAQLQELQVK[136.11].F sp|P35579|MYH9_HUMAN 1 1427.8319 0.96 83084 13844 2 1427.831207 714.9232 Myosin-9 OS=Homo sapiens OX=9606 GN=MYH9 PE=1 SV=4 6.14 2444.1 - 1.81E+06 - - - -0.4706 - 3.687 0.406 - 1178.7 1 2 0 -0.0007 12 0 0 0 2.68E+07 2.78E+07 - - - 5.4727 0.9999 221125_WJC_METTL3_EV_vs_WT_F06.13845.13845.2 1.64E-06 20/22 K.KVEAQLQELQVK.F sp|P35579|MYH9_HUMAN 1 1411.8035 0.96 83085 13845 2 1411.802004 706.909 Myosin-9 OS=Homo sapiens OX=9606 GN=MYH9 PE=1 SV=4 6.14 2444.2 - 1.32E+06 - - - -1.0448 - 3.657 0.432 - 1393.8 1 2 0 -0.0015 12 0 0 0 2.68E+07 2.78E+07 - - - 5.643 0.9999 221125_WJC_METTL3_EV_vs_WT_F06.13846.13846.2 1.17E-07 16/28 R.GGGGNFGPGPGSNFR[166.11].G "sp|P22626|ROA2_HUMAN,tr|A0A024RA28|A0A024RA28_HUMAN,tr|A0A7I2V4N1|A0A7I2V4N1_HUMAN,tr|A0A7I2V4I6|A0A7I2V4I6_HUMAN,tr|A0A7I2V4S4|A0A7I2V4S4_HUMAN,tr|A0A7I2V323|A0A7I2V323_HUMAN,tr|A0A7I2V3P1|A0A7I2V3P1_HUMAN,tr|A0A7I2V3P7|A0A7I2V3P7_HUMAN" 8 1386.6304 1.42 83086 13846 2 1386.629655 694.3225 Heterogeneous nuclear ribonucleoproteins A2\B1 OS=Homo sapiens OX=9606 GN=HNRNPA2B1 PE=1 SV=2 9.75 2444.3 - 1.12E+06 - - - -0.5596 - 2.884 0.526 - 630.2 1 2 0 -0.0008 15 0 0 0 1.42E+08 9.97E+07 - - - 5.5298 0.9999 221125_WJC_METTL3_EV_vs_WT_F06.13847.13847.2 1.23E-05 22-Dec K.GGHSSSLFGNIK.G sp|P33908|MA1A1_HUMAN 1 1202.6044 0.54 83087 13847 2 1202.6039 602.3095 "Mannosyl-oligosaccharide 1,2-alpha-mannosidase IA OS=Homo sapiens OX=9606 GN=MAN1A1 PE=1 SV=3" 8.76 2444.4 - 1.11E+06 - - - -0.4041 - 2.565 0.501 - 312.9 1 2 0 -0.0005 12 0 0 0 1.57E+07 2.89E+07 - - - 5.2197 0.9973 221125_WJC_METTL3_EV_vs_WT_F06.13848.13848.3 0.00675 16/64 R.LGSRPQPAEAYAEAVQR.L sp|Q5T447|HECD3_HUMAN 1 1841.9384 1.84 83088 13848 3 1841.944675 614.9867 E3 ubiquitin-protein ligase HECTD3 OS=Homo sapiens OX=9606 GN=HECTD3 PE=1 SV=1 6.14 2444.6 - 715551 - - - 3.4013 - 2.248 0.286 - 210.3 1 2 0 0.0063 17 0 0 0 4.36E+06 2.37E+06 - - - 3.7733 0.9997 221125_WJC_METTL3_EV_vs_WT_F06.13849.13849.3 0.000224 Sep-48 K.DHLIGPNDNDFGK[136.11].Y sp|Q8IWR0|Z3H7A_HUMAN 1 1448.6776 3.13 83089 13849 3 1448.676184 483.8998 Zinc finger CCCH domain-containing protein 7A OS=Homo sapiens OX=9606 GN=ZC3H7A PE=1 SV=1 4.41 2444.7 - 560255 - - - -0.9478 - 1.744 0.38 - 101.4 1 2 0 -0.0014 13 0 0 0 3.47E+07 1.11E+07 - - - 4.2842 0.939 221125_WJC_METTL3_EV_vs_WT_F06.13851.13851.2 8.94E-05 26-Nov T.VAGLAGKDPVQC[160.03]SR.D "sp|Q99497|PARK7_HUMAN,tr|K7ELW0|K7ELW0_HUMAN" 2 1456.7456 9.81 83091 13851 2 1456.745185 729.3801 Parkinson disease protein 7 OS=Homo sapiens OX=9606 GN=PARK7 PE=1 SV=2 8.19 2445 - 317484 - - - -0.3171 - 2.439 0.545 - 213.6 1 1 1 -0.0005 14 0 0 0 3.94E+06 4.02E+05 - - - 5.3036 0.9999 221125_WJC_METTL3_EV_vs_WT_F06.13854.13854.3 4.02E-05 14/48 R.NREEEWDPEYTPK.S "sp|Q9Y2W1|TR150_HUMAN,tr|A0A3B3ITZ9|A0A3B3ITZ9_HUMAN" 2 1691.7427 3.44 83092 13854 3 1691.741582 564.9215 Thyroid hormone receptor-associated protein 3 OS=Homo sapiens OX=9606 GN=THRAP3 PE=1 SV=2 4.25 2445.4 - 8.24E+06 - - - -0.6786 - 2.382 0.528 - 371.6 1 2 1 -0.0011 13 0 0 0 3.12E+08 9.08E+07 - - - 6.7796 0.9999 221125_WJC_METTL3_EV_vs_WT_F06.13855.13855.3 2.55E-05 Dec-44 K.K[136.11]VEAQLQELQVK[136.11].F sp|P35579|MYH9_HUMAN 1 1427.8319 0.91 83093 13855 3 1427.830064 476.9512 Myosin-9 OS=Homo sapiens OX=9606 GN=MYH9 PE=1 SV=4 6.14 2445.4 - 6.38E+06 - - - -1.2712 - 2.415 0.402 - 336.2 1 2 0 -0.0018 12 0 0 0 7.56E+07 8.30E+07 - - - 5.4653 1 221125_WJC_METTL3_EV_vs_WT_F06.13857.13857.3 5.12E-06 21/60 R.YRPYDGAASAYAQNYR.Y "sp|O15027|SC16A_HUMAN,tr|A0A3F2YNX0|A0A3F2YNX0_HUMAN,tr|A0A3F2YNZ0|A0A3F2YNZ0_HUMAN,tr|F1T0I1|F1T0I1_HUMAN" 4 1864.8493 0.54 83095 13857 3 1864.844175 622.6237 Protein transport protein Sec16A OS=Homo sapiens OX=9606 GN=SEC16A PE=1 SV=4 8.43 2445.6 - 1.67E+06 - - - -2.7268 - 3.984 0.578 - 646.2 1 2 0 -0.0051 16 0 0 0 2.65E+07 4.87E+07 - - - 8.5295 0.9422 221125_WJC_METTL3_EV_vs_WT_F06.13862.13862.3 0.109 Nov-32 K.STWLILHHK[136.11].V sp|P00167|CYB5_HUMAN 1 1141.6488 0.001 83100 13862 3 1141.648253 381.5569 Cytochrome b5 OS=Homo sapiens OX=9606 GN=CYB5A PE=1 SV=2 8.51 2446.3 - 324170 - - - -0.4467 - 1.698 0.057 - 162.6 1 2 0 -0.0005 9 0 0 0 0.00E+00 3.95E+06 - - - 0.771 1 221125_WJC_METTL3_EV_vs_WT_F06.13865.13865.3 1.31E-06 19/56 R.GLPNGMDADC[160.03]K[136.11]DFNR[166.11].T "sp|Q8TB72|PUM2_HUMAN,tr|A0A0C4DG68|A0A0C4DG68_HUMAN,tr|C9JW01|C9JW01_HUMAN" 3 1726.7522 1.41 83101 13865 3 1726.745395 576.5913 Pumilio homolog 2 OS=Homo sapiens OX=9606 GN=PUM2 PE=1 SV=2 4.43 2446.7 - 2.74E+06 - - - -3.9461 - 3.661 0.662 - 583.8 1 2 1 -0.0068 15 0 0 0 7.68E+07 5.44E+07 - - - 9.305 0.9994 221125_WJC_METTL3_EV_vs_WT_F06.13866.13866.3 0.000194 Sep-48 R.LLEGEDAHLTQYK.K "sp|Q04695|K1C17_HUMAN,tr|A0A3B3IS58|A0A3B3IS58_HUMAN,tr|F5GWP8|F5GWP8_HUMAN" 3 1515.7569 0.56 83102 13866 3 1515.753264 506.2596 "Keratin, type I cytoskeletal 17 OS=Homo sapiens OX=9606 GN=KRT17 PE=1 SV=2" 4.65 2446.8 - 3.29E+06 - - - -2.414 - 2.407 0.31 - 87.3 1 2 0 -0.0037 13 0 0 0 5.03E+07 8.99E+07 - - - 4.3767 1 221125_WJC_METTL3_EV_vs_WT_F06.13868.13868.3 7.20E-06 14/56 K.KAEAGAGSATEFQFR[166.11].G "sp|Q9NQ39|RS10L_HUMAN,sp|P46783|RS10_HUMAN" 2 1578.7666 - 83104 13868 3 1578.764391 527.2628 Putative 40S ribosomal protein S10-like OS=Homo sapiens OX=9606 GN=RPS10P5 PE=5 SV=1 6.14 2446.8 - 3.45E+06 - - - -1.3929 - 2.875 0.492 - 291.1 1 2 0 -0.0022 15 0 0 0 - - - - - 6.7803 1 221125_WJC_METTL3_EV_vs_WT_F06.13870.13870.2 1.32E-09 13/24 R.NREEEWDPEYTPK.S "sp|Q9Y2W1|TR150_HUMAN,tr|A0A3B3ITZ9|A0A3B3ITZ9_HUMAN" 2 1691.7427 5.56 83106 13870 2 1691.739473 846.8786 Thyroid hormone receptor-associated protein 3 OS=Homo sapiens OX=9606 GN=THRAP3 PE=1 SV=2 4.25 2447.1 - 1.04E+06 - - - -1.9252 - 2.728 0.698 - 439.6 1 2 1 -0.0033 13 0 0 0 3.17E+07 5.70E+06 - - - 6.7711 1 221125_WJC_METTL3_EV_vs_WT_F06.13871.13871.2 4.24E-07 18/26 K.QVSGGEDEIQQLQK.A "sp|Q6KC79|NIPBL_HUMAN,tr|A0A590UJS4|A0A590UJS4_HUMAN" 2 1557.7635 1.3 83107 13871 2 1557.756014 779.889 Nipped-B-like protein OS=Homo sapiens OX=9606 GN=NIPBL PE=1 SV=2 4.14 2447.2 - 1.03E+06 - - - -4.7831 - 2.99 0.573 - 930.9 1 2 0 -0.0075 14 0 0 0 2.31E+07 1.77E+07 - - - 6.0194 1 221125_WJC_METTL3_EV_vs_WT_F06.13878.13878.4 2.22E-06 16/84 K.KAEAGAGSATEFQFR.G "sp|Q9NQ39|RS10L_HUMAN,sp|P46783|RS10_HUMAN" 2 1568.7583 1.22 83112 13878 4 1568.755093 393.1969 Putative 40S ribosomal protein S10-like OS=Homo sapiens OX=9606 GN=RPS10P5 PE=5 SV=1 6.14 2448.1 - 874618 - - - -2.057 - 2.99 0.504 - 178.4 1 2 0 -0.0032 15 0 0 0 1.12E+07 9.13E+06 - - - 4.0038 0.9712 221125_WJC_METTL3_EV_vs_WT_F06.13879.13879.3 0.125 Sep-56 K.VTPQR[166.11]EEGEVTVC[160.03]FK[136.11].M sp|Q9UJW0|DCTN4_HUMAN 1 1795.8894 1.42 83113 13879 3 1795.895644 599.6371 Dynactin subunit 4 OS=Homo sapiens OX=9606 GN=DCTN4 PE=1 SV=1 4.79 2448.2 - 684246 - - - 3.5019 - 1.766 0.305 - 25.4 3 2 1 0.0063 15 0 0 0 1.02E+07 7.20E+06 - - - 3.2019 0.9999 221125_WJC_METTL3_EV_vs_WT_F06.13882.13882.3 0.000227 15/48 R.VAIHYINPPNPAK[136.11].D "sp|P78406|RAE1L_HUMAN,tr|E9PQ57|E9PQ57_HUMAN" 2 1440.7969 2.11 83115 13882 3 1440.793848 481.2729 mRNA export factor OS=Homo sapiens OX=9606 GN=RAE1 PE=1 SV=1 8.57 2448.6 - 1.70E+06 - - - -2.1072 - 2.887 0.412 - 384.5 1 2 0 -0.003 13 0 0 0 1.25E+08 5.92E+07 - - - 6.0071 0.9888 221125_WJC_METTL3_EV_vs_WT_F06.13884.13884.3 0.00026 13/48 R.PKEEEWDPEYTPK.S "sp|Q9NYF8|BCLF1_HUMAN,tr|H0YF14|H0YF14_HUMAN" 2 1646.7464 2.45 83116 13884 3 1646.747167 549.9227 Bcl-2-associated transcription factor 1 OS=Homo sapiens OX=9606 GN=BCLAF1 PE=1 SV=2 4.25 2448.8 - 6.31E+06 - - - 0.4548 - 2.688 0.503 - 259 1 1 1 0.0007 13 0 0 0 1.02E+08 4.19E+07 - - - 6.8287 1 221125_WJC_METTL3_EV_vs_WT_F06.13887.13887.2 2.63E-06 19/30 K.QTSSTPSSLALTSASR.L "sp|Q5SW79|CE170_HUMAN,tr|H0Y2V6|H0Y2V6_HUMAN" 2 1592.8006 1.25 83119 13887 2 1592.801865 797.4076 Centrosomal protein of 170 kDa OS=Homo sapiens OX=9606 GN=CEP170 PE=1 SV=1 9.75 2449.1 - 1.78E+06 - - - 0.8074 - 3.626 0.64 - 788.6 1 2 0 0.0013 16 0 0 0 4.12E+07 3.29E+07 - - - 6.9346 0.9988 221125_WJC_METTL3_EV_vs_WT_F06.13888.13888.3 0.00248 Sep-52 R.ERPSSAIYPSDSFR.Q "sp|Q92974|ARHG2_HUMAN,tr|A0A5F9ZI21|A0A5F9ZI21_HUMAN,tr|V9GZ14|V9GZ14_HUMAN,tr|V9GYM8|V9GYM8_HUMAN,tr|V9GYG5|V9GYG5_HUMAN,tr|V9GYF5|V9GYF5_HUMAN" 6 1610.7689 0.64 83120 13888 3 1610.771946 537.9302 Rho guanine nucleotide exchange factor 2 OS=Homo sapiens OX=9606 GN=ARHGEF2 PE=1 SV=4 6.17 2449.2 - 2.03E+06 - - - 1.9003 - 1.883 0.302 - 71.2 1 2 0 0.0031 14 0 0 0 1.85E+07 2.89E+07 - - - 3.588 1 221125_WJC_METTL3_EV_vs_WT_F06.13889.13889.3 7.71E-07 16/48 K.DHYSNGFC[160.03]TVYAK.T sp|P52907|CAZA1_HUMAN 1 1560.6667 15.51 83121 13889 3 1560.668828 521.2295 F-actin-capping protein subunit alpha-1 OS=Homo sapiens OX=9606 GN=CAPZA1 PE=1 SV=3 6.73 2449.3 - 1.00E+06 - - - 1.3456 - 2.454 0.474 - 238.5 1 2 0 0.0021 13 0 0 0 3.17E+07 2.04E+06 - - - 6.258 1 221125_WJC_METTL3_EV_vs_WT_F06.13891.13891.2 1.01E-08 13/34 K.SAESPTSPVTSETGSTFK[136.11].K sp|Q02952|AKA12_HUMAN 1 1819.8567 2.4 83123 13891 2 1819.854305 910.9356 A-kinase anchor protein 12 OS=Homo sapiens OX=9606 GN=AKAP12 PE=1 SV=4 4.53 2449.6 - 366553 - - - -1.3177 - 2.779 0.585 - 305.5 1 2 0 -0.0024 18 0 0 0 9.44E+06 3.94E+06 - - - 5.8739 0.9636 221125_WJC_METTL3_EV_vs_WT_F06.13896.13896.3 0.000334 13/48 R.PK[136.11]EEEWDPEYTPK[136.11].S "sp|Q9NYF8|BCLF1_HUMAN,tr|H0YF14|H0YF14_HUMAN" 2 1662.7748 2.46 83126 13896 3 1662.771995 555.2655 Bcl-2-associated transcription factor 1 OS=Homo sapiens OX=9606 GN=BCLAF1 PE=1 SV=2 4.25 2450.1 - 2.24E+06 - - - -1.6978 - 2.33 0.449 - 302.3 1 1 1 -0.0028 13 0 0 0 1.02E+08 4.16E+07 - - - 5.8385 1 221125_WJC_METTL3_EV_vs_WT_F06.13897.13897.2 9.15E-06 17/28 R.SANAEDAQEFSDVER.A sp|Q9HCY8|S10AE_HUMAN 1 1666.7071 999 83127 13897 2 1666.705521 834.3608 Protein S100-A14 OS=Homo sapiens OX=9606 GN=S100A14 PE=1 SV=1 3.83 2450.3 - 1.16E+06 - - - -0.9306 - 3.793 0.691 - 1320 1 2 0 -0.0016 15 0 0 0 4.73E+07 0.00E+00 - - - 7.4219 1 221125_WJC_METTL3_EV_vs_WT_F06.13901.13901.2 1.76E-11 18/30 K.DVQDSLTVSNEAQTAK.E sp|P52907|CAZA1_HUMAN 1 1704.8166 1.15 83129 13901 2 1704.817015 853.4156 F-actin-capping protein subunit alpha-1 OS=Homo sapiens OX=9606 GN=CAPZA1 PE=1 SV=3 4.03 2450.8 - 749073 - - - 0.2299 - 3.744 0.723 - 1231.1 1 2 0 0.0004 16 0 0 0 5.36E+07 4.67E+07 - - - 7.6266 1 221125_WJC_METTL3_EV_vs_WT_F06.13902.13902.3 1.27E-07 Dec-44 R.AQVQEFC[160.03]DYGTK[136.11].E "sp|Q86U44|MTA70_HUMAN,tr|H0YFV6|H0YFV6_HUMAN" 2 1452.6435 0.05 83130 13902 3 1452.640322 485.2218 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 4.37 2450.9 - 1.32E+06 - - - -2.174 - 2.347 0.587 - 151.8 1 2 0 -0.0032 12 0 0 0 6.98E+06 1.43E+08 - - - 7.4484 1 221125_WJC_METTL3_EV_vs_WT_F06.13909.13909.3 7.32E-08 15/48 R.VAIHYINPPNPAK.D "sp|P78406|RAE1L_HUMAN,tr|E9PQ57|E9PQ57_HUMAN" 2 1432.7827 2.09 83135 13909 3 1432.783599 478.6015 mRNA export factor OS=Homo sapiens OX=9606 GN=RAE1 PE=1 SV=1 8.57 2451.7 - 2.46E+06 - - - 0.6386 - 2.831 0.522 - 355.2 1 2 0 0.0009 13 0 0 0 1.32E+08 6.32E+07 - - - 7.181 1 221125_WJC_METTL3_EV_vs_WT_F06.13910.13910.2 9.20E-11 18/30 K.DVQDSLTVSNEAQTAK[136.11].E sp|P52907|CAZA1_HUMAN 1 1712.8308 1.14 83136 13910 2 1712.831467 857.4227 F-actin-capping protein subunit alpha-1 OS=Homo sapiens OX=9606 GN=CAPZA1 PE=1 SV=3 4.03 2451.9 - 1.34E+06 - - - 0.376 - 3.585 0.701 - 1146.1 1 2 0 0.0006 16 0 0 0 5.41E+07 4.74E+07 - - - 7.3574 0.9919 221125_WJC_METTL3_EV_vs_WT_F06.13911.13911.3 0.0443 Sep-40 R.YYTVFDRDNNR.V "sp|P07339|CATD_HUMAN,tr|A0A1B0GW44|A0A1B0GW44_HUMAN,tr|A0A1B0GVD5|A0A1B0GVD5_HUMAN,tr|A0A1B0GV23|A0A1B0GV23_HUMAN,tr|C9JH19|C9JH19_HUMAN,tr|H7C469|H7C469_HUMAN,tr|A0A1B0GWE8|A0A1B0GWE8_HUMAN,tr|A0A1B0GVP3|A0A1B0GVP3_HUMAN,tr|F8W787|F8W787_HUMAN" 9 1461.6637 2.5 83137 13911 3 1461.662064 488.2285 Cathepsin D OS=Homo sapiens OX=9606 GN=CTSD PE=1 SV=1 5.96 2451.9 - 1.19E+06 - - - -1.1131 - 1.555 0.283 - 73.4 1 2 1 -0.0016 11 0 0 0 2.90E+07 1.16E+07 - - - 2.9489 0.9996 221125_WJC_METTL3_EV_vs_WT_F06.13912.13912.3 0.00271 Oct-52 K.SSPHASLGGFPVEK.Y sp|P35453|HXD13_HUMAN 1 1411.7096 2.26 83138 13912 3 1411.712338 471.5771 Homeobox protein Hox-D13 OS=Homo sapiens OX=9606 GN=HOXD13 PE=1 SV=3 6.47 2452 - 1.02E+06 - - - 1.9544 - 1.959 0.379 - 78 1 2 0 0.0028 14 0 0 0 4.81E+07 2.13E+07 - - - 4.5517 0.9972 221125_WJC_METTL3_EV_vs_WT_F06.13913.13913.3 0.000149 Dec-48 K.TADGFAVPEPPK[136.11]R[166.11].K sp|Q86XP3|DDX42_HUMAN 1 1401.7371 2.45 83139 13913 3 1401.743509 468.253 ATP-dependent RNA helicase DDX42 OS=Homo sapiens OX=9606 GN=DDX42 PE=1 SV=1 5.74 2452.1 - 823102 - - - 4.5479 - 1.883 0.375 - 154 1 2 0 0.0064 13 0 0 0 9.66E+07 3.94E+07 - - - 4.435 0.9999 221125_WJC_METTL3_EV_vs_WT_F06.13915.13915.3 4.39E-05 13/44 K.KLPPLPVVEKPK.L "sp|Q9NUL3|STAU2_HUMAN,tr|E5RJN7|E5RJN7_HUMAN,tr|E7EVJ4|E7EVJ4_HUMAN,tr|E7EVI1|E7EVI1_HUMAN,tr|E7EPX0|E7EPX0_HUMAN" 5 1343.8541 1.59 83141 13915 3 1343.855298 448.9586 Double-stranded RNA-binding protein Staufen homolog 2 OS=Homo sapiens OX=9606 GN=STAU2 PE=1 SV=2 9.7 2452.4 - 495677 - - - 0.9227 - 2.104 0.415 - 231.9 1 2 0 0.0012 12 0 0 0 8.20E+06 5.15E+06 - - - 5.2283 0.993 221125_WJC_METTL3_EV_vs_WT_F06.13923.13923.2 2.55E-07 22-Oct R.AQVQEFC[160.03]DYGTK.E "sp|Q86U44|MTA70_HUMAN,tr|H0YFV6|H0YFV6_HUMAN" 2 1444.6293 0.02 83147 13923 2 1445.629998 723.3219 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 4.37 2453.2 - 2.25E+06 - - - 692.7161 - 2.37 0.608 - 275.6 1 2 0 1.0007 12 0 0 0 1.01E+08 4.55E+09 - - - 5.4879 1 221125_WJC_METTL3_EV_vs_WT_F06.13927.13927.2 2.78E-06 20-Dec R.DTNFGTNC[160.03]IC[160.03]R[166.11].V "sp|P41223|BUD31_HUMAN,tr|C9JCD9|C9JCD9_HUMAN" 2 1366.5633 10.04 83151 13927 2 1366.558562 684.2889 Protein BUD31 homolog OS=Homo sapiens OX=9606 GN=BUD31 PE=1 SV=2 5.82 2453.7 - 681753 - - - -3.4956 - 2.431 0.657 - 602.8 1 2 0 -0.0048 11 0 0 0 7.50E+07 7.47E+06 - - - 6.2952 0.9998 221125_WJC_METTL3_EV_vs_WT_F06.13930.13930.3 0.000325 Oct-60 K.DVQDSLTVSNEAQTAK.E sp|P52907|CAZA1_HUMAN 1 1704.8166 0.68 83152 13930 3 1704.816708 569.2795 F-actin-capping protein subunit alpha-1 OS=Homo sapiens OX=9606 GN=CAPZA1 PE=1 SV=3 4.03 2454.1 - 1.85E+06 - - - 0.0499 - 2.334 0.36 - 111.1 1 2 0 0.0001 16 0 0 0 3.04E+07 4.49E+07 - - - 4.7284 0.9995 221125_WJC_METTL3_EV_vs_WT_F06.13933.13933.3 0.002 13/48 K.TNGGFVELGPC[160.03]HR.M "sp|Q86SF2|GALT7_HUMAN,tr|H0YAK0|H0YAK0_HUMAN,tr|H0YAH3|H0YAH3_HUMAN" 3 1442.6725 2.11 83155 13933 3 1442.669644 481.8981 N-acetylgalactosaminyltransferase 7 OS=Homo sapiens OX=9606 GN=GALNT7 PE=1 SV=1 6.41 2454.4 - 1.12E+06 - - - -1.9672 - 2.457 0.289 - 250.7 1 2 0 -0.0028 13 0 0 0 9.84E+07 4.65E+07 - - - 4.1986 0.982 221125_WJC_METTL3_EV_vs_WT_F06.13934.13934.4 0.358 Oct-84 K.K[136.11]MVDPEK[136.11]PQLGMIDR[166.11].W "sp|P09874|PARP1_HUMAN,tr|A0A7I2V5E9|A0A7I2V5E9_HUMAN,tr|A0A7I2V625|A0A7I2V625_HUMAN,tr|A0A7I2V3E1|A0A7I2V3E1_HUMAN" 4 1781.9378 1 83156 13934 4 1781.935683 446.4917 Poly [ADP-ribose] polymerase 1 OS=Homo sapiens OX=9606 GN=PARP1 PE=1 SV=4 6.12 2454.5 - 1.09E+06 - - - -1.2054 - 1.739 0.177 - 57.9 1 2 0 -0.0021 15 0 0 0 1.78E+07 1.77E+07 - - - 0.964 1 221125_WJC_METTL3_EV_vs_WT_F06.13936.13936.3 1.59E-07 16/68 K.LSLEGDHSTPPSAYGSVK.A "sp|P07355|ANXA2_HUMAN,sp|A6NMY6|AXA2L_HUMAN,tr|H0YMU9|H0YMU9_HUMAN,tr|H0YMD9|H0YMD9_HUMAN,tr|H0YKX9|H0YKX9_HUMAN,tr|H0YMM1|H0YMM1_HUMAN,tr|H0YLV6|H0YLV6_HUMAN,tr|H0YMD0|H0YMD0_HUMAN,tr|H0YKV8|H0YKV8_HUMAN,tr|H0YMW4|H0YMW4_HUMAN,tr|H0YKN4|H0YKN4_HUMAN,tr|H0YN42|H0YN42_HUMAN,tr|A0A7I2V4P4|A0A7I2V4P4_HUMAN,tr|H0YMT9|H0YMT9_HUMAN,tr|H0YKZ7|H0YKZ7_HUMAN,tr|H0YKL9|H0YKL9_HUMAN,tr|H0YNB8|H0YNB8_HUMAN,tr|H0YKS4|H0YKS4_HUMAN" 18 1843.8952 2.06 83158 13936 3 1843.896598 615.639 Annexin A2 OS=Homo sapiens OX=9606 GN=ANXA2 PE=1 SV=2 5.32 2454.7 - 931384 - - - 0.7538 - 3 0.52 - 282.4 1 2 0 0.0014 18 0 0 0 3.69E+07 1.79E+07 - - - 7.0728 1 221125_WJC_METTL3_EV_vs_WT_F06.13938.13938.3 0.000222 Oct-48 R.AGESGHTVADYLK[136.11].F "sp|Q13627|DYR1A_HUMAN,tr|A0A2R8Y6L5|A0A2R8Y6L5_HUMAN,tr|A0A2R8YDF3|A0A2R8YDF3_HUMAN,tr|A0A2R8Y6I6|A0A2R8Y6I6_HUMAN" 4 1354.6608 0.77 83160 13938 3 1354.660069 452.5609 Dual specificity tyrosine-phosphorylation-regulated kinase 1A OS=Homo sapiens OX=9606 GN=DYRK1A PE=1 SV=2 5.32 2454.9 - 683731 - - - -0.5721 - 2.218 0.498 - 112.5 1 2 0 -0.0008 13 0 0 0 6.15E+06 8.00E+06 - - - 6.2518 0.9999 221125_WJC_METTL3_EV_vs_WT_F06.13943.13943.2 0.000206 16/26 R.EQQIVIQSSGGLSK[136.11].D "sp|P38646|GRP75_HUMAN,tr|A0A7I2V2S7|A0A7I2V2S7_HUMAN,tr|A0A7I2V2G2|A0A7I2V2G2_HUMAN,tr|H0Y8S0|H0Y8S0_HUMAN,tr|A0A7I2V3F7|A0A7I2V3F7_HUMAN,tr|A0A7I2YQB2|A0A7I2YQB2_HUMAN,tr|D6RCD7|D6RCD7_HUMAN" 7 1480.7977 0.42 83163 13943 2 1480.796604 741.4061 "Stress-70 protein, mitochondrial OS=Homo sapiens OX=9606 GN=HSPA9 PE=1 SV=2" 6.1 2455.6 - 1.32E+06 - - - -0.7212 - 2.812 0.536 - 839.7 1 2 0 -0.0011 14 0 0 0 5.82E+07 1.40E+08 - - - 5.5941 1 221125_WJC_METTL3_EV_vs_WT_F06.13946.13946.3 3.10E-06 15/52 K.SSPHASLGGFPVEK[136.11].Y sp|P35453|HXD13_HUMAN 1 1419.7238 2.23 83166 13946 3 1419.723732 474.2485 Homeobox protein Hox-D13 OS=Homo sapiens OX=9606 GN=HOXD13 PE=1 SV=3 6.47 2455.9 - 876022 - - - -0.0331 - 2.542 0.448 - 181.5 1 2 0 0 14 0 0 0 4.74E+07 2.13E+07 - - - 6.0141 1 221125_WJC_METTL3_EV_vs_WT_F06.13947.13947.3 4.58E-11 21/68 K.LSLEGDHSTPPSAYGSVK[136.11].A "sp|P07355|ANXA2_HUMAN,sp|A6NMY6|AXA2L_HUMAN,tr|H0YMU9|H0YMU9_HUMAN,tr|H0YMD9|H0YMD9_HUMAN,tr|H0YKX9|H0YKX9_HUMAN,tr|H0YMM1|H0YMM1_HUMAN,tr|H0YLV6|H0YLV6_HUMAN,tr|H0YMD0|H0YMD0_HUMAN,tr|H0YKV8|H0YKV8_HUMAN,tr|H0YMW4|H0YMW4_HUMAN,tr|H0YKN4|H0YKN4_HUMAN,tr|H0YN42|H0YN42_HUMAN,tr|A0A7I2V4P4|A0A7I2V4P4_HUMAN,tr|H0YMT9|H0YMT9_HUMAN,tr|H0YKZ7|H0YKZ7_HUMAN,tr|H0YKL9|H0YKL9_HUMAN,tr|H0YNB8|H0YNB8_HUMAN,tr|H0YKS4|H0YKS4_HUMAN" 18 1851.9094 1.83 83167 13947 3 1851.908011 618.3104 Annexin A2 OS=Homo sapiens OX=9606 GN=ANXA2 PE=1 SV=2 5.32 2456 - 834968 - - - -0.7544 - 3.473 0.621 - 543 1 2 0 -0.0014 18 0 0 0 2.82E+07 1.54E+07 - - - 8.5634 1 221125_WJC_METTL3_EV_vs_WT_F06.13948.13948.2 3.52E-11 15/30 R.SSESLPAAAEEAPEPR[166.11].C "sp|O94761|RECQ4_HUMAN,tr|V9GYB6|V9GYB6_HUMAN" 2 1649.7772 0.94 83168 13948 2 1649.77853 825.8959 ATP-dependent DNA helicase Q4 OS=Homo sapiens OX=9606 GN=RECQL4 PE=1 SV=2 4.09 2456.1 - 697759 - - - 0.7977 - 3.31 0.694 - 462.6 1 2 0 0.0013 16 0 0 0 1.26E+07 1.35E+07 - - - 7.1092 1 221125_WJC_METTL3_EV_vs_WT_F06.13949.13949.2 8.59E-10 15/30 R.SSESLPAAAEEAPEPR.C "sp|O94761|RECQ4_HUMAN,tr|V9GYB6|V9GYB6_HUMAN" 2 1639.7689 0.92 83169 13949 2 1639.780579 820.8917 ATP-dependent DNA helicase Q4 OS=Homo sapiens OX=9606 GN=RECQL4 PE=1 SV=2 4.09 2456.2 - 621270 - - - 7.0955 - 2.845 0.622 - 442.7 1 2 0 0.0116 16 0 0 0 1.16E+07 1.27E+07 - - - 6.202 0.9998 221125_WJC_METTL3_EV_vs_WT_F06.13955.13955.2 0.00806 14/26 R.EQQIVIQSSGGLSK.D "sp|P38646|GRP75_HUMAN,tr|A0A7I2V2S7|A0A7I2V2S7_HUMAN,tr|A0A7I2V2G2|A0A7I2V2G2_HUMAN,tr|H0Y8S0|H0Y8S0_HUMAN,tr|A0A7I2V3F7|A0A7I2V3F7_HUMAN,tr|A0A7I2YQB2|A0A7I2YQB2_HUMAN,tr|D6RCD7|D6RCD7_HUMAN" 7 1472.7835 0.42 83173 13955 2 1472.782275 737.399 "Stress-70 protein, mitochondrial OS=Homo sapiens OX=9606 GN=HSPA9 PE=1 SV=2" 6.1 2457 - 1.30E+06 - - - -0.8127 - 2.492 0.416 - 654.3 1 2 0 -0.0012 14 0 0 0 5.90E+07 1.41E+08 - - - 4.4045 0.871 221125_WJC_METTL3_EV_vs_WT_F06.13960.13960.3 0.676 Oct-36 R.LFTVQIPHKR.L "sp|Q9HCU5|PREB_HUMAN,tr|H7C2N7|H7C2N7_HUMAN,tr|H7C0W3|H7C0W3_HUMAN" 3 1237.7295 0.64 83178 13960 3 1237.727558 413.5838 Prolactin regulatory element-binding protein OS=Homo sapiens OX=9606 GN=PREB PE=1 SV=2 11 2457.6 - 384483 - - - -1.5908 - 1.429 0.079 - 91.7 1 2 0 -0.002 10 0 0 0 3.61E+06 5.67E+06 - - - 0.4628 0.9999 221125_WJC_METTL3_EV_vs_WT_F06.13966.13966.2 9.95E-05 13/22 R.AQVQEFC[160.03]DYGTK[136.11].E "sp|Q86U44|MTA70_HUMAN,tr|H0YFV6|H0YFV6_HUMAN" 2 1452.6435 0.02 83182 13966 2 1452.643839 727.329 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 4.37 2458.4 - 2.49E+08 - - - 0.2471 - 2.679 0.532 - 531.4 1 2 0 0.0004 12 0 0 0 1.01E+08 4.55E+09 - - - 5.5631 0.9997 221125_WJC_METTL3_EV_vs_WT_F06.13972.13972.3 0.000105 15/48 K.TKAPDDLVAPVVK.K sp|O43172|PRP4_HUMAN 1 1351.7711 2.45 83188 13972 3 1351.769475 451.5976 U4\U6 small nuclear ribonucleoprotein Prp4 OS=Homo sapiens OX=9606 GN=PRPF4 PE=1 SV=2 5.63 2459 - 814811 - - - -1.2147 - 2.626 0.421 - 281.3 1 2 1 -0.0016 13 0 0 0 2.69E+07 1.10E+07 - - - 5.8509 0.9997 221125_WJC_METTL3_EV_vs_WT_F06.13974.13974.3 1.38E-05 15/60 R.LAEFSSQAAEEEEKVK.S "sp|Q7Z406|MYH14_HUMAN,tr|A0A0C4DFM8|A0A0C4DFM8_HUMAN" 2 1793.8683 1.42 83190 13974 3 1793.86934 598.9634 Myosin-14 OS=Homo sapiens OX=9606 GN=MYH14 PE=1 SV=2 4.33 2459.3 - 349115 - - - 0.5664 - 2.522 0.433 - 142.9 1 2 1 0.001 16 0 0 0 6.29E+06 4.42E+06 - - - 5.7408 0.8146 221125_WJC_METTL3_EV_vs_WT_F06.13977.13977.3 2.21 Jul-44 K.SNNVEETEIHWK.L "sp|Q9UK61|TASOR_HUMAN,tr|A0A087X0F1|A0A087X0F1_HUMAN" 2 1484.6896 0.73 83191 13977 3 1484.689125 495.9038 Protein TASOR OS=Homo sapiens OX=9606 GN=TASOR PE=1 SV=3 4.75 2459.7 - 1.25E+06 - - - -0.3011 - 1.21 0.089 - 44.5 1 2 0 -0.0004 12 0 0 0 9.30E+06 1.28E+07 - - - 0.0605 0.9998 221125_WJC_METTL3_EV_vs_WT_F06.13980.13980.3 0.0207 17/44 R.TGHSLLHTLYGR.S "sp|P31040|SDHA_HUMAN,tr|D6RFM5|D6RFM5_HUMAN,tr|A0A494C1T6|A0A494C1T6_HUMAN" 3 1353.7153 0.76 83194 13980 3 1353.715121 452.2457 "Succinate dehydrogenase [ubiquinone] flavoprotein subunit, mitochondrial OS=Homo sapiens OX=9606 GN=SDHA PE=1 SV=2" 8.47 2459.9 - 1.25E+06 - - - -0.1566 - 2.393 0.32 - 372.5 1 2 0 -0.0002 12 0 0 0 3.46E+07 4.57E+07 - - - 4.5262 1 221125_WJC_METTL3_EV_vs_WT_F06.13981.13981.3 1.43E-09 14/52 K.DVDDDGEEK[136.11]ELMER[166.11].L "sp|Q8NE71|ABCF1_HUMAN,tr|A0A0G2JIC2|A0A0G2JIC2_HUMAN,tr|Q5STZ8|Q5STZ8_HUMAN,tr|A0A0G2JJB9|A0A0G2JJB9_HUMAN" 4 1696.7217 1.01 83195 13981 3 1696.722399 566.5812 ATP-binding cassette sub-family F member 1 OS=Homo sapiens OX=9606 GN=ABCF1 PE=1 SV=2 3.85 2460 - 1.10E+06 - - - 0.4238 - 2.536 0.638 - 157.2 1 2 1 0.0007 14 0 0 0 1.61E+07 1.59E+07 - - - 8.1259 0.9987 221125_WJC_METTL3_EV_vs_WT_F06.13982.13982.3 0.00144 28/92 R.PAPVAQPPAAAPPSAVGSSAAAPR.Q "sp|Q5T1J5|CHCH9_HUMAN,sp|Q9Y6H1|CHCH2_HUMAN" 2 2137.128 3.8 83196 13982 3 2137.130059 713.3833 "Putative coiled-coil-helix-coiled-coil-helix domain-containing protein CHCHD2P9, mitochondrial OS=Homo sapiens OX=9606 GN=CHCHD2P9 PE=5 SV=1" 10.18 2460.1 - 1.09E+06 - - - 0.9625 - 4.192 0.551 - 746.3 1 1 0 0.0021 24 0 0 0 1.52E+07 3.99E+06 - - - 8.0112 0.9998 221125_WJC_METTL3_EV_vs_WT_F06.13983.13983.2 2.68E-07 Dec-32 R.NSQFAGGPLGNPNTTAK.V "sp|O75694|NU155_HUMAN,tr|E9PF10|E9PF10_HUMAN" 2 1672.8169 1.67 83197 13983 2 1672.813951 837.4157 Nuclear pore complex protein Nup155 OS=Homo sapiens OX=9606 GN=NUP155 PE=1 SV=1 8.75 2460.2 - 823153 - - - -1.7617 - 2.755 0.46 - 254.4 1 2 0 -0.0029 17 0 0 0 1.69E+07 1.01E+07 - - - 4.9292 1 221125_WJC_METTL3_EV_vs_WT_F06.13984.13984.2 3.85E-08 24-Nov K.SSVNC[160.03]PFSSQDMK.Y sp|Q08211|DHX9_HUMAN 1 1485.6228 0.89 83198 13984 2 1485.62412 743.8187 ATP-dependent RNA helicase A OS=Homo sapiens OX=9606 GN=DHX9 PE=1 SV=4 5.55 2460.3 - 1.55E+06 - - - 0.8791 - 2.188 0.64 - 207.9 1 2 0 0.0013 13 0 0 0 1.93E+07 2.17E+07 - - - 5.7772 0.9914 221125_WJC_METTL3_EV_vs_WT_F06.13990.13990.3 0.00366 Dec-52 R.EQQIVIQSSGGLSK[136.11].D "sp|P38646|GRP75_HUMAN,tr|A0A7I2V2S7|A0A7I2V2S7_HUMAN,tr|A0A7I2V2G2|A0A7I2V2G2_HUMAN,tr|H0Y8S0|H0Y8S0_HUMAN,tr|A0A7I2V3F7|A0A7I2V3F7_HUMAN,tr|A0A7I2YQB2|A0A7I2YQB2_HUMAN,tr|D6RCD7|D6RCD7_HUMAN" 7 1480.7977 0.47 83202 13990 3 1480.804616 494.6065 "Stress-70 protein, mitochondrial OS=Homo sapiens OX=9606 GN=HSPA9 PE=1 SV=2" 6.1 2461.1 - 1.89E+06 - - - 4.6894 - 2.003 0.29 - 235.3 1 2 0 0.0069 14 0 0 0 9.61E+06 2.05E+07 - - - 3.6173 0.9999 221125_WJC_METTL3_EV_vs_WT_F06.13992.13992.3 2.46E-05 15/48 K.TNGGFVELGPC[160.03]HR[166.11].M "sp|Q86SF2|GALT7_HUMAN,tr|H0YAK0|H0YAK0_HUMAN,tr|H0YAH3|H0YAH3_HUMAN" 3 1452.6808 2.48 83204 13992 3 1452.684206 485.2342 N-acetylgalactosaminyltransferase 7 OS=Homo sapiens OX=9606 GN=GALNT7 PE=1 SV=1 6.41 2461.2 - 3.32E+06 - - - 2.3777 - 2.429 0.481 - 222.6 1 2 0 0.0035 13 0 0 0 9.11E+07 3.67E+07 - - - 6.3079 1 221125_WJC_METTL3_EV_vs_WT_F06.13995.13995.2 1.76E-11 15/24 K.SSVNC[160.03]PFSSQDMK[136.11].Y sp|Q08211|DHX9_HUMAN 1 1493.637 0.89 83207 13995 2 1493.63834 747.8258 ATP-dependent RNA helicase A OS=Homo sapiens OX=9606 GN=DHX9 PE=1 SV=4 5.55 2461.6 - 992754 - - - 0.8878 - 3.101 0.529 - 789.7 1 2 0 0.0013 13 0 0 0 1.93E+07 2.17E+07 - - - 5.8524 0.9999 221125_WJC_METTL3_EV_vs_WT_F06.13996.13996.3 4.85E-06 15/52 K.DVDDDGEEKELMER.L "sp|Q8NE71|ABCF1_HUMAN,tr|A0A0G2JIC2|A0A0G2JIC2_HUMAN,tr|Q5STZ8|Q5STZ8_HUMAN,tr|A0A0G2JJB9|A0A0G2JJB9_HUMAN" 4 1678.6992 0.82 83208 13996 3 1678.701846 560.5737 ATP-binding cassette sub-family F member 1 OS=Homo sapiens OX=9606 GN=ABCF1 PE=1 SV=2 3.85 2461.7 - 971466 - - - 1.5703 - 2.407 0.585 - 236.6 1 2 1 0.0026 14 0 0 0 1.21E+07 1.47E+07 - - - 7.3958 1 221125_WJC_METTL3_EV_vs_WT_F06.14000.14000.2 6.49E-10 15/32 R.NSQFAGGPLGNPNTTAK[136.11].V "sp|O75694|NU155_HUMAN,tr|E9PF10|E9PF10_HUMAN" 2 1680.8311 1.67 83212 14000 2 1680.833852 841.4228 Nuclear pore complex protein Nup155 OS=Homo sapiens OX=9606 GN=NUP155 PE=1 SV=1 8.75 2462.2 - 658541 - - - 1.6385 - 3.09 0.665 - 675.3 1 2 0 0.0028 17 0 0 0 1.69E+07 1.01E+07 - - - 6.7255 0.9999 221125_WJC_METTL3_EV_vs_WT_F06.14002.14002.2 0.00139 22-Aug R.ISVYYNEATGGK[136.11].Y "sp|P07437|TBB5_HUMAN,tr|Q5JP53|Q5JP53_HUMAN" 2 1308.6441 0.21 83214 14002 2 1308.644739 655.3293 Tubulin beta chain OS=Homo sapiens OX=9606 GN=TUBB PE=1 SV=2 6 2462.4 - 323090 - - - 0.4638 - 1.924 0.534 - 146.7 1 2 0 0.0006 12 0 0 0 4.33E+05 2.06E+06 - - - 4.7068 0.9988 221125_WJC_METTL3_EV_vs_WT_F06.14003.14003.3 0.314 Dec-36 R.RIDISPSTLR.K "sp|Q9NYF8|BCLF1_HUMAN,tr|E9PKI6|E9PKI6_HUMAN,tr|A0A1W2PQ43|A0A1W2PQ43_HUMAN,tr|E9PK91|E9PK91_HUMAN,tr|E9PK09|E9PK09_HUMAN,tr|E9PQN2|E9PQN2_HUMAN" 6 1156.6564 2.17 83215 14003 3 1156.657488 386.5594 Bcl-2-associated transcription factor 1 OS=Homo sapiens OX=9606 GN=BCLAF1 PE=1 SV=2 9.6 2462.5 - 226894 - - - 0.9225 - 2.19 0.213 - 245.7 1 2 0 0.0011 10 0 0 0 3.62E+06 1.67E+06 - - - 3.2038 1 221125_WJC_METTL3_EV_vs_WT_F06.14007.14007.3 2.26E-06 16/60 K.LHVGNISPTC[160.03]TNQELR.A "sp|Q9BQ04|RBM4B_HUMAN,tr|E9PM61|E9PM61_HUMAN,tr|U3KQD5|U3KQD5_HUMAN,tr|E9PLB0|E9PLB0_HUMAN" 4 1837.9105 1.55 83217 14007 3 1837.914635 613.6441 RNA-binding protein 4B OS=Homo sapiens OX=9606 GN=RBM4B PE=1 SV=1 6.74 2463.1 - 3.62E+06 - - - 2.2602 - 3.38 0.572 - 563.3 1 2 0 0.0042 16 0 0 0 7.79E+08 5.04E+08 - - - 8.041 0.9994 221125_WJC_METTL3_EV_vs_WT_F06.14010.14010.3 0.00039 14/36 R.EQVNDLFSRK.F "sp|P78347|GTF2I_HUMAN,sp|Q86UP8|GTD2A_HUMAN,sp|Q6EKJ0|GTD2B_HUMAN,tr|A0A494C1N8|A0A494C1N8_HUMAN,tr|A0A087WW90|A0A087WW90_HUMAN,tr|A0A0D9SF80|A0A0D9SF80_HUMAN,tr|A0A494C0I1|A0A494C0I1_HUMAN,tr|A0A494C1K3|A0A494C1K3_HUMAN" 8 1234.6306 1.4 83220 14010 3 1234.63254 412.5508 General transcription factor II-I OS=Homo sapiens OX=9606 GN=GTF2I PE=1 SV=2 6.17 2463.3 - 938837 - - - 1.5713 - 2.082 0.294 - 263.8 1 2 0 0.0019 10 0 0 0 9.79E+06 6.99E+06 - - - 3.9589 0.9815 221125_WJC_METTL3_EV_vs_WT_F06.14012.14012.2 0.000393 20-Oct K.NQSQGYNQWQQ.G "sp|Q00839|HNRPU_HUMAN,tr|A0A1W2PQL0|A0A1W2PQL0_HUMAN,tr|A0A1W2PPL4|A0A1W2PPL4_HUMAN,tr|A0A087WZF3|A0A087WZF3_HUMAN,tr|Q5RI18|Q5RI18_HUMAN,tr|A0A1W2PP35|A0A1W2PP35_HUMAN,tr|A0A1W2PPS1|A0A1W2PPS1_HUMAN,tr|A0A1W2PPH7|A0A1W2PPH7_HUMAN,tr|A0A1W2PP34|A0A1W2PP34_HUMAN,tr|A0A1X7SBS1|A0A1X7SBS1_HUMAN" 10 1379.5854 - 83222 14012 2 1379.587329 690.8 Heterogeneous nuclear ribonucleoprotein U OS=Homo sapiens OX=9606 GN=HNRNPU PE=1 SV=6 5.52 2463.5 - 688936 - - - 1.3685 - 2.051 0.423 - 285.9 1 1 0 0.0019 11 0 0 0 - - - - - 4.1079 0.9997 221125_WJC_METTL3_EV_vs_WT_F06.14013.14013.3 1.68E-05 15/64 K.IITVEK[136.11]HPDADSLYVEK[136.11].L "sp|P54577|SYYC_HUMAN,tr|A0A6Q8PFX2|A0A6Q8PFX2_HUMAN" 2 1972.0488 0.79 83223 14013 3 1972.050287 658.3569 "Tyrosine--tRNA ligase, cytoplasmic OS=Homo sapiens OX=9606 GN=YARS1 PE=1 SV=4" 4.75 2463.6 - 520421 - - - 0.75 - 2.321 0.433 - 173 1 2 1 0.0015 17 0 0 0 2.19E+07 2.76E+07 - - - 5.4943 0.9989 221125_WJC_METTL3_EV_vs_WT_F06.14014.14014.2 0.0118 Aug-36 R.SAVQKPPSTGSAPAIESVD.- sp|Q9NUQ3|TXLNG_HUMAN 1 1839.9214 0.94 83224 14014 2 1839.925002 920.968 Gamma-taxilin OS=Homo sapiens OX=9606 GN=TXLNG PE=1 SV=2 4.67 2463.7 - 296937 - - - 1.9457 - 1.787 0.346 - 132.4 1 2 0 0.0036 19 0 0 0 6.95E+06 7.42E+06 - - - 3.0227 0.9999 221125_WJC_METTL3_EV_vs_WT_F06.14016.14016.3 0.00107 14/44 R.TGHSLLHTLYGR[166.11].S "sp|P31040|SDHA_HUMAN,tr|D6RFM5|D6RFM5_HUMAN,tr|A0A494C1T6|A0A494C1T6_HUMAN" 3 1363.7236 0.73 83225 14016 3 1363.725766 455.5818 "Succinate dehydrogenase [ubiquinone] flavoprotein subunit, mitochondrial OS=Homo sapiens OX=9606 GN=SDHA PE=1 SV=2" 8.47 2464 - 4.47E+06 - - - 1.5861 - 2.378 0.438 - 190.3 1 2 0 0.0022 12 0 0 0 3.33E+07 4.56E+07 - - - 5.8238 0.999 221125_WJC_METTL3_EV_vs_WT_F06.14017.14017.3 0.0194 Oct-48 K.TADGFAVPEPPKR.K sp|Q86XP3|DDX42_HUMAN 1 1383.7147 2.35 83226 14017 3 1383.717873 462.2455 ATP-dependent RNA helicase DDX42 OS=Homo sapiens OX=9606 GN=DDX42 PE=1 SV=1 5.74 2464 - 1.35E+06 - - - 2.3191 - 2.15 0.301 - 139.3 1 2 0 0.0032 13 0 0 0 9.25E+07 3.94E+07 - - - 3.9704 1 221125_WJC_METTL3_EV_vs_WT_F06.14019.14019.3 1.50E-09 22/80 R.LPLSTPSPGNGSQGSHPLVSR.T sp|Q6ZU65|UBN2_HUMAN 1 2087.076 1.62 83228 14019 3 2087.079816 696.6993 Ubinuclein-2 OS=Homo sapiens OX=9606 GN=UBN2 PE=1 SV=2 9.76 2464.3 - 439822 - - - 1.8447 - 3.887 0.61 - 473.6 1 2 0 0.0039 21 0 0 0 7.76E+06 4.80E+06 - - - 8.5947 0.9998 221125_WJC_METTL3_EV_vs_WT_F06.14021.14021.4 0.00333 Oct-72 R.FSQPLHEEIALHR[166.11].R sp|O95382|M3K6_HUMAN 1 1585.824 0.28 83230 14021 4 1585.825914 397.4633 Mitogen-activated protein kinase kinase kinase 6 OS=Homo sapiens OX=9606 GN=MAP3K6 PE=1 SV=3 6 2464.5 - 184008 - - - 1.1786 - 2.044 0.385 - 41.6 1 2 0 0.0019 13 0 0 0 3.55E+05 1.27E+06 - - - 2.8416 1 221125_WJC_METTL3_EV_vs_WT_F06.14023.14023.3 1.46E-06 16/56 K.K[136.11]AEAGAGSATEFQFR[166.11].G "sp|Q9NQ39|RS10L_HUMAN,sp|P46783|RS10_HUMAN" 2 1586.7808 1.28 83231 14023 3 1586.784604 529.9342 Putative 40S ribosomal protein S10-like OS=Homo sapiens OX=9606 GN=RPS10P5 PE=5 SV=1 6.14 2464.7 - 6.19E+06 - - - 2.4036 - 2.932 0.549 - 416.1 1 2 0 0.0038 15 0 0 0 4.69E+09 3.68E+09 - - - 7.4666 1 221125_WJC_METTL3_EV_vs_WT_F06.14025.14025.2 4.29E-06 15/24 R.NQGGSSWEAPYSR.S sp|Q5BKZ1|ZN326_HUMAN 1 1437.6273 0.91 83232 14025 2 1437.629981 719.8209 DBIRD complex subunit ZNF326 OS=Homo sapiens OX=9606 GN=ZNF326 PE=1 SV=2 6 2464.9 - 1.42E+06 - - - 1.8607 - 2.712 0.581 - 1012.1 1 2 0 0.0027 13 0 0 0 8.33E+07 9.15E+07 - - - 5.892 0.9998 221125_WJC_METTL3_EV_vs_WT_F06.14026.14026.3 0.00349 13/40 R.LHLGHTFSLSK[136.11].C "sp|Q9P2J5|SYLC_HUMAN,tr|A0A6I8PIV1|A0A6I8PIV1_HUMAN,tr|A0A6I8PRS0|A0A6I8PRS0_HUMAN,tr|A0A6I8PLB8|A0A6I8PLB8_HUMAN,tr|A0A6I8PIP7|A0A6I8PIP7_HUMAN,tr|A0A6I8PIT3|A0A6I8PIT3_HUMAN,tr|A0A6I8PTV8|A0A6I8PTV8_HUMAN,tr|A0A6I8PRU9|A0A6I8PRU9_HUMAN,tr|A0A6I8PLB3|A0A6I8PLB3_HUMAN,tr|A0A6I8PS05|A0A6I8PS05_HUMAN,tr|B4DER1|B4DER1_HUMAN,tr|A0A6I8PL42|A0A6I8PL42_HUMAN" 12 1246.6914 0.86 83233 14026 3 1246.693211 416.5711 "Leucine--tRNA ligase, cytoplasmic OS=Homo sapiens OX=9606 GN=LARS1 PE=1 SV=2" 8.76 2465 - 995893 - - - 1.4871 - 2.319 0.364 - 209.5 1 2 0 0.0019 11 0 0 0 1.03E+07 1.19E+07 - - - 4.9873 1 221125_WJC_METTL3_EV_vs_WT_F06.14027.14027.3 1.24E-06 14/56 R.NPGNQAAYEHFETMK.N sp|P18206|VINC_HUMAN 1 1735.7624 4.53 83234 14027 3 1735.762489 579.5947 Vinculin OS=Homo sapiens OX=9606 GN=VCL PE=1 SV=4 5.4 2465.2 - 597306 - - - 0.0403 - 2.799 0.49 - 242.3 1 2 0 0.0001 15 0 0 0 9.13E+06 2.02E+06 - - - 6.6887 0.9999 221125_WJC_METTL3_EV_vs_WT_F06.14028.14028.3 0.000128 Dec-36 K.RNVIEAVYSR.L "sp|O75688|PPM1B_HUMAN,tr|B8ZZF0|B8ZZF0_HUMAN,tr|A0A3B3IS24|A0A3B3IS24_HUMAN,tr|C9JIR6|C9JIR6_HUMAN" 4 1205.6517 3.84 83235 14028 3 1205.653876 402.8912 Protein phosphatase 1B OS=Homo sapiens OX=9606 GN=PPM1B PE=1 SV=1 8.75 2465.3 - 571024 - - - 1.8297 - 2.687 0.44 - 250 1 2 0 0.0022 10 0 0 0 3.95E+06 1.03E+06 - - - 6.3316 0.9988 221125_WJC_METTL3_EV_vs_WT_F06.14029.14029.2 1.42E-05 30-Dec K.LHVGNISPTC[160.03]TNQELR[166.11].A "sp|Q9BQ04|RBM4B_HUMAN,tr|E9PM61|E9PM61_HUMAN,tr|U3KQD5|U3KQD5_HUMAN,tr|E9PLB0|E9PLB0_HUMAN" 4 1847.9188 1.6 83236 14029 2 1847.926647 924.9667 RNA-binding protein 4B OS=Homo sapiens OX=9606 GN=RBM4B PE=1 SV=1 6.74 2465.4 - 409729 - - - 4.2729 - 2.345 0.54 - 356.8 1 2 0 0.0079 16 0 0 0 3.79E+07 2.38E+07 - - - 5.1223 0.9998 221125_WJC_METTL3_EV_vs_WT_F06.14030.14030.3 3.48E-05 14/68 R.TSLHTASSTMYSNTNPLR.S sp|Q7Z353|HDX_HUMAN 1 1979.9371 0.84 83237 14030 3 1979.941576 660.9863 Highly divergent homeobox OS=Homo sapiens OX=9606 GN=HDX PE=1 SV=1 8.44 2465.6 - 373505 - - - 2.2662 - 2.587 0.414 - 146.2 1 2 0 0.0045 18 0 0 0 3.07E+06 3.64E+06 - - - 5.5213 0.9985 221125_WJC_METTL3_EV_vs_WT_F06.14031.14031.4 0.00951 13/72 K.VSEGIDFVHHYGR[166.11].A "sp|P18074|ERCC2_HUMAN,tr|A8MX75|A8MX75_HUMAN,tr|E7EVE9|E7EVE9_HUMAN,tr|A0A804HK53|A0A804HK53_HUMAN" 4 1524.7349 0.02 83238 14031 4 1524.73936 382.191 General transcription and DNA repair factor IIH helicase subunit XPD OS=Homo sapiens OX=9606 GN=ERCC2 PE=1 SV=1 5.99 2465.7 - 316158 - - - 2.9277 - 2.407 0.323 - 121.1 1 2 0 0.0045 13 0 0 0 4.95E+04 2.23E+06 - - - 2.3618 0.9999 221125_WJC_METTL3_EV_vs_WT_F06.14032.14032.3 2.15E-05 18/56 R.NPGNQAAYEHFETMK[136.11].N sp|P18206|VINC_HUMAN 1 1743.7766 4.45 83239 14032 3 1743.780539 582.2661 Vinculin OS=Homo sapiens OX=9606 GN=VCL PE=1 SV=4 5.4 2465.8 - 274706 - - - 2.248 - 3.37 0.434 - 383.6 1 2 0 0.0039 15 0 0 0 8.97E+06 2.02E+06 - - - 6.5477 1 221125_WJC_METTL3_EV_vs_WT_F06.14037.14037.3 5.16E-09 18/56 K.KAEAGAGSATEFQFR.G "sp|Q9NQ39|RS10L_HUMAN,sp|P46783|RS10_HUMAN" 2 1568.7583 1.28 83243 14037 3 1568.762122 523.9267 Putative 40S ribosomal protein S10-like OS=Homo sapiens OX=9606 GN=RPS10P5 PE=5 SV=1 6.14 2466.4 - 8.13E+06 - - - 2.4236 - 3.138 0.633 - 520.2 1 2 0 0.0038 15 0 0 0 4.69E+09 3.68E+09 - - - 8.5803 1 221125_WJC_METTL3_EV_vs_WT_F06.14038.14038.3 9.57E-07 13/60 K.LHVGNISPTC[160.03]TNQELR[166.11].A "sp|Q9BQ04|RBM4B_HUMAN,tr|E9PM61|E9PM61_HUMAN,tr|U3KQD5|U3KQD5_HUMAN,tr|E9PLB0|E9PLB0_HUMAN" 4 1847.9188 1.55 83244 14038 3 1847.921333 616.9802 RNA-binding protein 4B OS=Homo sapiens OX=9606 GN=RBM4B PE=1 SV=1 6.74 2466.4 - 1.29E+07 - - - 1.3972 - 3.18 0.581 - 256.1 1 2 0 0.0026 16 0 0 0 7.79E+08 5.04E+08 - - - 7.9853 0.9999 221125_WJC_METTL3_EV_vs_WT_F06.14040.14040.3 2.29E-05 15/48 R.MLWMDKEKEESMK.E "sp|P0CG22|DR4L1_HUMAN,sp|Q9BTZ2|DHRS4_HUMAN,tr|H0YNP7|H0YNP7_HUMAN,tr|A0A087WXI8|A0A087WXI8_HUMAN" 4 1683.767 0.3 83246 14040 3 1683.768558 562.263 Putative dehydrogenase\reductase SDR family member 4-like 1 OS=Homo sapiens OX=9606 GN=DHRS4L1 PE=5 SV=1 4.87 2466.5 - 1.18E+06 - - - 0.9039 - 3.156 0.543 - 301.1 1 2 2 0.0015 13 0 0 0 1.39E+07 4.69E+07 - - - 7.7096 0.9998 221125_WJC_METTL3_EV_vs_WT_F06.14041.14041.3 4.85E-09 20/64 K.IITVEKHPDADSLYVEK.L "sp|P54577|SYYC_HUMAN,tr|A0A6Q8PFX2|A0A6Q8PFX2_HUMAN" 2 1956.0204 0.79 83247 14041 3 1956.02583 653.0141 "Tyrosine--tRNA ligase, cytoplasmic OS=Homo sapiens OX=9606 GN=YARS1 PE=1 SV=4" 4.75 2466.6 - 1.12E+06 - - - 2.772 - 2.982 0.62 - 424.3 1 2 1 0.0054 17 0 0 0 2.19E+07 2.76E+07 - - - 8.2111 0.9999 221125_WJC_METTL3_EV_vs_WT_F06.14042.14042.3 7.92E-07 16/44 K.IHEEFSEHALLR[166.11].K "sp|Q9Y2L1|RRP44_HUMAN,tr|G3V1J5|G3V1J5_HUMAN" 2 1489.7553 1.31 83248 14042 3 1489.760598 497.5924 Exosome complex exonuclease RRP44 OS=Homo sapiens OX=9606 GN=DIS3 PE=1 SV=2 5.33 2466.7 - 1.11E+06 - - - 3.5583 - 2.928 0.574 - 304.3 1 2 0 0.0053 12 0 0 0 4.10E+07 3.12E+07 - - - 7.9159 0.9179 221125_WJC_METTL3_EV_vs_WT_F06.14044.14044.2 3.04E-09 13/22 K.GAVHDVKDVLDS.V sp|P81605|DCD_HUMAN 1 1253.6252 999 83250 14044 2 1253.625339 627.8199 Dermcidin OS=Homo sapiens OX=9606 GN=DCD PE=1 SV=2 4.41 2466.9 - 1.07E+06 - - - 0.126 - 2.828 0.397 - 496.8 1 1 1 0.0002 12 0 0 0 7.03E+07 0.00E+00 - - - 4.7085 0.9992 221125_WJC_METTL3_EV_vs_WT_F06.14045.14045.3 0.0019 Nov-56 R.FQEYHIQQNEALAAK.A sp|Q9Y5J7|TIM9_HUMAN 1 1788.8795 1.27 83251 14045 3 1788.884852 597.3004 Mitochondrial import inner membrane translocase subunit Tim9 OS=Homo sapiens OX=9606 GN=TIMM9 PE=1 SV=1 5.4 2467 - 1.06E+06 - - - 2.9929 - 2.034 0.371 - 69.6 1 2 0 0.0054 15 0 0 0 8.72E+06 6.88E+06 - - - 4.5275 0.8674 221125_WJC_METTL3_EV_vs_WT_F06.14047.14047.2 8.18E-06 14/26 K.GEATVSFDDPPSAK[136.11].A "sp|P35637|FUS_HUMAN,sp|Q92804|RBP56_HUMAN,tr|H3BPE7|H3BPE7_HUMAN,tr|A0A075B7D9|A0A075B7D9_HUMAN" 4 1427.666 1.29 83253 14047 2 1428.677593 714.8403 RNA-binding protein FUS OS=Homo sapiens OX=9606 GN=FUS PE=1 SV=1 4.03 2467.2 - 611776 - - - 708.5719 - 2.584 0.531 - 443.3 1 2 0 1.0116 14 0 0 0 3.69E+07 2.87E+07 - - - 5.0276 0.9965 221125_WJC_METTL3_EV_vs_WT_F06.14051.14051.2 6.27E-06 26-Sep K.SESLSDNATAFSNR[166.11].S sp|O75379|VAMP4_HUMAN 1 1507.6778 1.44 83257 14051 2 1507.669854 754.8462 Vesicle-associated membrane protein 4 OS=Homo sapiens OX=9606 GN=VAMP4 PE=1 SV=2 4.37 2467.7 - 166419 - - - -5.2936 - 1.938 0.514 - 236.1 1 2 0 -0.008 14 0 0 0 2.49E+06 1.74E+06 - - - 4.4953 1 221125_WJC_METTL3_EV_vs_WT_F06.14052.14052.2 1.52E-06 30-Dec R.NFSNMDDEENYSAASK.A sp|O43264|ZW10_HUMAN 1 1820.7159 1.76 83258 14052 2 1820.721164 911.3652 Centromere\kinetochore protein zw10 homolog OS=Homo sapiens OX=9606 GN=ZW10 PE=1 SV=3 3.92 2467.8 - 132117 - - - 2.8785 - 2.882 0.713 - 386.8 1 2 0 0.0052 16 0 0 0 7.00E+05 3.96E+05 - - - 6.9079 0.9999 221125_WJC_METTL3_EV_vs_WT_F06.14055.14055.3 0.000311 Dec-52 R.FAQHGTFEYEYSQR[166.11].W "sp|P23246|SFPQ_HUMAN,tr|H0Y9K7|H0Y9K7_HUMAN" 2 1771.783 0.81 83260 14055 3 1771.784615 591.6016 "Splicing factor, proline- and glutamine-rich OS=Homo sapiens OX=9606 GN=SFPQ PE=1 SV=2" 5.4 2468.1 - 1.08E+06 - - - 0.9296 - 1.927 0.436 - 172.7 1 2 0 0.0016 14 0 0 0 3.67E+08 4.53E+08 - - - 5.1438 1 221125_WJC_METTL3_EV_vs_WT_F06.14060.14060.2 6.99E-13 17/30 K.LHVGNISPTC[160.03]TNQELR.A "sp|Q9BQ04|RBM4B_HUMAN,tr|E9PM61|E9PM61_HUMAN,tr|U3KQD5|U3KQD5_HUMAN,tr|E9PLB0|E9PLB0_HUMAN" 4 1837.9105 1.47 83265 14060 2 1837.91174 919.9625 RNA-binding protein 4B OS=Homo sapiens OX=9606 GN=RBM4B PE=1 SV=1 6.74 2468.4 - 876512 - - - 0.685 - 3.333 0.599 - 811.9 1 2 0 0.0013 16 0 0 0 3.43E+07 2.34E+07 - - - 6.4246 0.9997 221125_WJC_METTL3_EV_vs_WT_F06.14062.14062.3 3.58E-06 15/52 R.FAQHGTFEYEYSQR.W "sp|P23246|SFPQ_HUMAN,tr|H0Y9K7|H0Y9K7_HUMAN" 2 1761.7747 0.81 83267 14062 3 1761.783386 588.2655 "Splicing factor, proline- and glutamine-rich OS=Homo sapiens OX=9606 GN=SFPQ PE=1 SV=2" 5.4 2468.7 - 603848 - - - 4.9314 - 2.54 0.541 - 252.4 1 2 0 0.0087 14 0 0 0 3.66E+08 4.52E+08 - - - 7.0465 0.9988 221125_WJC_METTL3_EV_vs_WT_F06.14065.14065.2 0.000433 24-Sep R.IQFKPDDGISPER.A sp|Q96I24|FUBP3_HUMAN 1 1500.7573 2.22 83270 14065 2 1500.761681 751.3859 Far upstream element-binding protein 3 OS=Homo sapiens OX=9606 GN=FUBP3 PE=1 SV=2 4.56 2469 - 376522 - - - 2.9478 - 2.036 0.39 - 190.4 1 2 0 0.0044 13 0 0 0 4.71E+07 2.12E+07 - - - 3.7449 0.9251 221125_WJC_METTL3_EV_vs_WT_F06.14072.14072.4 0.104 Oct-96 K.IITVEK[136.11]HPDADSLYVEK[136.11].L "sp|P54577|SYYC_HUMAN,tr|A0A6Q8PFX2|A0A6Q8PFX2_HUMAN" 2 1972.0488 0.73 83275 14072 4 1972.050554 494.0195 "Tyrosine--tRNA ligase, cytoplasmic OS=Homo sapiens OX=9606 GN=YARS1 PE=1 SV=4" 4.75 2469.8 - 3.71E+06 - - - 0.8854 - 1.598 0.177 - 61.5 1 2 1 0.0017 17 0 0 0 2.60E+07 3.54E+07 - - - 0.9289 0.9999 221125_WJC_METTL3_EV_vs_WT_F06.14073.14073.3 0.000407 15/52 K.VLHFDQVTENTTEK.A "sp|P48594|SPB4_HUMAN,tr|C9JZ65|C9JZ65_HUMAN,tr|H0Y5H9|H0Y5H9_HUMAN" 3 1659.8104 53.25 83276 14073 3 1659.812685 554.2774 Serpin B4 OS=Homo sapiens OX=9606 GN=SERPINB4 PE=1 SV=2 4.65 2469.8 - 3.02E+06 - - - 1.3676 - 2.665 0.443 - 460.6 1 2 0 0.0023 14 0 0 0 5.70E+07 1.07E+06 - - - 6.0833 0.9025 221125_WJC_METTL3_EV_vs_WT_F06.14074.14074.3 0.000539 Nov-60 Q.WSPHNETILASSGTDR.R "sp|Q09028|RBBP4_HUMAN,sp|Q16576|RBBP7_HUMAN,tr|H0YCT5|H0YCT5_HUMAN,tr|H0YDK2|H0YDK2_HUMAN,tr|Q5JP02|Q5JP02_HUMAN,tr|H0YEU5|H0YEU5_HUMAN,tr|Q5JP01|Q5JP01_HUMAN,tr|H0YF10|H0YF10_HUMAN,tr|E9PC52|E9PC52_HUMAN" 9 1769.8333 1.57 83277 14074 3 1769.836592 590.9517 Histone-binding protein RBBP4 OS=Homo sapiens OX=9606 GN=RBBP4 PE=1 SV=3 5.32 2469.9 - 2.26E+06 - - - 1.8736 - 1.95 0.311 - 155.5 1 1 0 0.0033 16 0 0 0 3.82E+07 2.43E+07 - - - 3.72 0.9958 221125_WJC_METTL3_EV_vs_WT_F06.14076.14076.3 0.0538 13/36 R.R[166.11]K[136.11]PFYPALIR[166.11].Y "sp|O00746|NDKM_HUMAN,tr|Q4TT34|Q4TT34_HUMAN,tr|H0Y6J0|H0Y6J0_HUMAN,tr|F2Z2X0|F2Z2X0_HUMAN,tr|A2IDC9|A2IDC9_HUMAN" 5 1287.781 1.88 83279 14076 3 1287.783041 430.2676 "Nucleoside diphosphate kinase, mitochondrial OS=Homo sapiens OX=9606 GN=NME4 PE=1 SV=1" 11 2470 - 2.06E+06 - - - 1.5833 - 1.548 0.251 - 232.6 1 2 0 0.002 10 0 0 0 3.22E+08 1.71E+08 - - - 2.614 0.9898 221125_WJC_METTL3_EV_vs_WT_F06.14077.14077.3 0.00068 Dec-60 Q.WSPHNETILASSGTDR[166.11].R "sp|Q09028|RBBP4_HUMAN,sp|Q16576|RBBP7_HUMAN,tr|H0YCT5|H0YCT5_HUMAN,tr|H0YDK2|H0YDK2_HUMAN,tr|Q5JP02|Q5JP02_HUMAN,tr|H0YEU5|H0YEU5_HUMAN,tr|Q5JP01|Q5JP01_HUMAN,tr|H0YF10|H0YF10_HUMAN,tr|E9PC52|E9PC52_HUMAN" 9 1779.8415 1.57 83280 14077 3 1779.845087 594.2878 Histone-binding protein RBBP4 OS=Homo sapiens OX=9606 GN=RBBP4 PE=1 SV=3 5.32 2470.1 - 1.76E+06 - - - 1.9895 - 2.438 0.454 - 198.6 1 1 0 0.0035 16 0 0 0 3.82E+07 2.43E+07 - - - 5.8873 1 221125_WJC_METTL3_EV_vs_WT_F06.14079.14079.2 8.43E-05 17/30 K.QQEVVVAGSSLPTSSK[136.11].V sp|Q9H3P7|GCP60_HUMAN 1 1623.8559 0.83 83282 14079 2 1623.85571 812.9352 Golgi resident protein GCP60 OS=Homo sapiens OX=9606 GN=ACBD3 PE=1 SV=4 6 2470.3 - 1.20E+06 - - - -0.1262 - 2.95 0.603 - 781.5 1 2 0 -0.0002 16 0 0 0 2.12E+07 2.55E+07 - - - 6.1544 0.9986 221125_WJC_METTL3_EV_vs_WT_F06.14081.14081.3 0.00066 Dec-48 R.AQIEQVIANC[160.03]EHK.N sp|Q92621|NU205_HUMAN 1 1538.7511 2.6 83284 14081 3 1538.753646 513.9243 Nuclear pore complex protein Nup205 OS=Homo sapiens OX=9606 GN=NUP205 PE=1 SV=3 5.4 2470.5 - 824234 - - - 1.637 - 2.251 0.235 - 210 1 2 0 0.0025 13 0 0 0 6.77E+06 2.61E+06 - - - 3.3592 1 221125_WJC_METTL3_EV_vs_WT_F06.14083.14083.2 2.53E-06 16/30 K.QQEVVVAGSSLPTSSK.V sp|Q9H3P7|GCP60_HUMAN 1 1615.8417 0.83 83286 14083 2 1615.841747 808.9281 Golgi resident protein GCP60 OS=Homo sapiens OX=9606 GN=ACBD3 PE=1 SV=4 6 2470.7 - 811362 - - - 0.0198 - 3.11 0.64 - 621.2 1 2 0 0 16 0 0 0 2.12E+07 2.55E+07 - - - 6.5576 0.9998 221125_WJC_METTL3_EV_vs_WT_F06.14084.14084.3 4.54E-06 15/40 K.RLDYITAEIKR.Y sp|O15212|PFD6_HUMAN 1 1376.7776 2.89 83287 14084 3 1376.777633 459.9331 Prefoldin subunit 6 OS=Homo sapiens OX=9606 GN=PFDN6 PE=1 SV=1 8.59 2470.9 - 584449 - - - 0.0247 - 2.382 0.329 - 496.9 1 2 0 0 11 0 0 0 1.04E+08 3.58E+07 - - - 4.6737 0.9991 221125_WJC_METTL3_EV_vs_WT_F06.14085.14085.3 0.00303 13/52 K.FELSENC[160.03]SERPGLR.G "sp|Q14203|DCTN1_HUMAN,tr|A0A804CDA6|A0A804CDA6_HUMAN,tr|E7EX90|E7EX90_HUMAN,tr|A0A7P0Z4C3|A0A7P0Z4C3_HUMAN,tr|Q6AWB1|Q6AWB1_HUMAN" 5 1692.789 1.23 83288 14085 3 1692.79124 565.2703 Dynactin subunit 1 OS=Homo sapiens OX=9606 GN=DCTN1 PE=1 SV=3 4.79 2471 - 560979 - - - 1.3416 - 2.167 0.269 - 195.9 1 2 0 0.0023 14 0 0 0 5.86E+07 4.75E+07 - - - 3.5936 1 221125_WJC_METTL3_EV_vs_WT_F06.14090.14090.3 3.42E-06 15/48 R.IQFKPDDGISPER.A sp|Q96I24|FUBP3_HUMAN 1 1500.7573 1.92 83292 14090 3 1500.758814 501.2597 Far upstream element-binding protein 3 OS=Homo sapiens OX=9606 GN=FUBP3 PE=1 SV=2 4.56 2471.5 - 2.16E+07 - - - 1.0375 - 3.005 0.459 - 301.7 1 2 0 0.0016 13 0 0 0 5.99E+08 3.11E+08 - - - 6.6401 0.998 221125_WJC_METTL3_EV_vs_WT_F06.14091.14091.3 0.000373 Nov-36 R.RKPFYPALIR.Y "sp|O00746|NDKM_HUMAN,tr|Q4TT34|Q4TT34_HUMAN,tr|H0Y6J0|H0Y6J0_HUMAN,tr|F2Z2X0|F2Z2X0_HUMAN,tr|A2IDC9|A2IDC9_HUMAN" 5 1259.7503 1.88 83293 14091 3 1259.749459 420.924 "Nucleoside diphosphate kinase, mitochondrial OS=Homo sapiens OX=9606 GN=NME4 PE=1 SV=1" 11 2471.6 - 4.68E+06 - - - -0.6374 - 1.997 0.205 - 170.7 1 2 0 -0.0008 10 0 0 0 3.22E+08 1.71E+08 - - - 2.8452 1 221125_WJC_METTL3_EV_vs_WT_F06.14092.14092.3 2.37E-07 20/64 R.AQVQEFC[160.03]DYGTK[136.11]EEC[160.03]MK[136.11].A "sp|Q86U44|MTA70_HUMAN,tr|H0YFV6|H0YFV6_HUMAN" 2 2137.909 0.001 83294 14092 3 2137.902988 713.6436 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 4.41 2471.6 - 3.90E+06 - - - -2.7948 - 3.972 0.668 - 452.4 1 2 1 -0.006 17 0 0 0 0.00E+00 2.47E+07 - - - 9.4703 1 221125_WJC_METTL3_EV_vs_WT_F06.14094.14094.2 8.00E-07 14/24 R.ANENSNIQVLSER[166.11].S sp|Q6UN15|FIP1_HUMAN 1 1482.7302 1.08 83296 14094 2 1482.729419 742.3724 Pre-mRNA 3'-end-processing factor FIP1 OS=Homo sapiens OX=9606 GN=FIP1L1 PE=1 SV=1 4.53 2471.8 - 1.66E+06 - - - -0.5301 - 2.687 0.6 - 829.2 1 2 0 -0.0008 13 0 0 0 4.03E+07 3.72E+07 - - - 6.0092 1 221125_WJC_METTL3_EV_vs_WT_F06.14095.14095.2 3.43E-09 14/24 R.ANENSNIQVLSER.S sp|Q6UN15|FIP1_HUMAN 1 1472.7219 1.08 83297 14095 2 1472.719861 737.3682 Pre-mRNA 3'-end-processing factor FIP1 OS=Homo sapiens OX=9606 GN=FIP1L1 PE=1 SV=1 4.53 2471.9 - 1.49E+06 - - - -1.4083 - 2.922 0.623 - 911.2 1 2 0 -0.0021 13 0 0 0 4.03E+07 3.72E+07 - - - 6.3938 1 221125_WJC_METTL3_EV_vs_WT_F06.14096.14096.3 0.0207 17/52 R.SFEEEFGTASDKER.V "sp|Q9BZJ0|CRNL1_HUMAN,tr|Q5JY65|Q5JY65_HUMAN" 2 1630.7111 1.69 83298 14096 3 1630.709187 544.5776 Crooked neck-like protein 1 OS=Homo sapiens OX=9606 GN=CRNKL1 PE=1 SV=4 4.25 2472 - 1.34E+06 - - - -1.17 - 2.95 0.638 - 303.4 1 2 1 -0.0019 14 0 0 0 5.94E+07 3.51E+07 - - - 8.5275 0.9998 221125_WJC_METTL3_EV_vs_WT_F06.14097.14097.2 1.73E-05 24-Nov R.IQFK[136.11]PDDGISPER[166.11].A sp|Q96I24|FUBP3_HUMAN 1 1518.7797 2.22 83299 14097 2 1518.778405 760.3971 Far upstream element-binding protein 3 OS=Homo sapiens OX=9606 GN=FUBP3 PE=1 SV=2 4.56 2472.1 - 873478 - - - -0.8711 - 2.143 0.473 - 317.9 1 2 0 -0.0013 13 0 0 0 4.71E+07 2.12E+07 - - - 4.4904 0.888 221125_WJC_METTL3_EV_vs_WT_F06.14098.14098.3 2.9 Aug-48 K.VSDQK[136.11]PLGSWSVK[136.11].Q "sp|Q9H8H0|NOL11_HUMAN,tr|J3QLQ6|J3QLQ6_HUMAN" 2 1445.7849 1.17 83300 14098 3 1445.78535 482.9356 Nucleolar protein 11 OS=Homo sapiens OX=9606 GN=NOL11 PE=1 SV=1 8.56 2472.2 - 570202 - - - 0.2912 - 1.428 0.098 - 52.5 3 2 0 0.0004 13 0 0 0 3.31E+07 2.83E+07 - - - 0.3776 0.9999 221125_WJC_METTL3_EV_vs_WT_F06.14108.14108.3 2.28E-09 18/52 R.SFEEEFGTASDK[136.11]ER[166.11].V "sp|Q9BZJ0|CRNL1_HUMAN,tr|Q5JY65|Q5JY65_HUMAN" 2 1648.7336 1.69 83308 14108 3 1648.733836 550.5851 Crooked neck-like protein 1 OS=Homo sapiens OX=9606 GN=CRNKL1 PE=1 SV=4 4.25 2473.1 - 1.89E+06 - - - 0.1644 - 3.319 0.549 - 333.3 1 2 1 0.0003 14 0 0 0 5.94E+07 3.51E+07 - - - 7.8489 0.9824 221125_WJC_METTL3_EV_vs_WT_F06.14109.14109.3 0.0788 Jul-32 K.SKWDEEWDK.N sp|Q14677|EPN4_HUMAN 1 1221.5302 1.59 83309 14109 3 1221.529768 408.184 Clathrin interactor 1 OS=Homo sapiens OX=9606 GN=CLINT1 PE=1 SV=1 4.32 2473.2 - 1.72E+06 - - - -0.3684 - 1.379 0.259 - 74.8 1 2 1 -0.0004 9 0 0 0 6.20E+07 3.89E+07 - - - 2.396 0.9965 221125_WJC_METTL3_EV_vs_WT_F06.14110.14110.3 0.0126 Oct-32 K.SK[136.11]WDEEWDK[136.11].N sp|Q14677|EPN4_HUMAN 1 1237.5586 1.56 83310 14110 3 1237.558364 413.5268 Clathrin interactor 1 OS=Homo sapiens OX=9606 GN=CLINT1 PE=1 SV=1 4.32 2473.3 - 1.28E+06 - - - -0.2052 - 1.692 0.303 - 165.9 1 2 1 -0.0003 9 0 0 0 6.09E+07 3.89E+07 - - - 3.5031 1 221125_WJC_METTL3_EV_vs_WT_F06.14111.14111.3 9.78E-05 16/40 K.R[166.11]LDYITAEIK[136.11]R[166.11].Y sp|O15212|PFD6_HUMAN 1 1404.8083 2.91 83311 14111 3 1404.808025 469.2767 Prefoldin subunit 6 OS=Homo sapiens OX=9606 GN=PFDN6 PE=1 SV=1 8.59 2473.4 - 1.07E+06 - - - -0.2235 - 3.376 0.417 - 460.9 1 2 0 -0.0003 11 0 0 0 1.04E+08 3.58E+07 - - - 6.6455 1 221125_WJC_METTL3_EV_vs_WT_F06.14115.14115.2 7.12E-06 16/28 K.KAEAGAGSATEFQFR.G "sp|Q9NQ39|RS10L_HUMAN,sp|P46783|RS10_HUMAN" 2 1568.7583 0.52 83315 14115 2 1568.762768 785.3864 Putative 40S ribosomal protein S10-like OS=Homo sapiens OX=9606 GN=RPS10P5 PE=5 SV=1 6.14 2473.9 - 430182 - - - 2.8354 - 3.657 0.595 - 808.3 1 2 0 0.0044 15 0 0 0 5.37E+06 1.03E+07 - - - 6.6221 1 221125_WJC_METTL3_EV_vs_WT_F06.14119.14119.3 4.34E-07 16/60 K.AVHNSVAAQLTGVAGH.- sp|Q9NUD5|ZCHC3_HUMAN 1 1530.7903 - 83317 14119 3 1530.791017 511.2707 Zinc finger CCHC domain-containing protein 3 OS=Homo sapiens OX=9606 GN=ZCCHC3 PE=1 SV=2 6.96 2474.4 - 4.12E+06 - - - 0.4756 - 3.171 0.55 - 435.4 1 2 0 0.0007 16 0 0 0 - - - - - 7.6329 1 221125_WJC_METTL3_EV_vs_WT_F06.14127.14127.2 4.62E-05 26-Dec R.SFEEEFGTASDKER.V "sp|Q9BZJ0|CRNL1_HUMAN,tr|Q5JY65|Q5JY65_HUMAN" 2 1630.7111 3.37 83325 14127 2 1630.710631 816.3628 Crooked neck-like protein 1 OS=Homo sapiens OX=9606 GN=CRNKL1 PE=1 SV=4 4.25 2475.2 - 278851 - - - -0.2845 - 2.677 0.686 - 419.3 1 2 1 -0.0005 14 0 0 0 2.54E+06 7.54E+05 - - - 6.5787 0.9999 221125_WJC_METTL3_EV_vs_WT_F06.14133.14133.3 3.95E-05 15/76 R.AEGPVAVVVNGHTEGPAPAR.S sp|Q86UK7|ZN598_HUMAN 1 1926.9912 7.39 83329 14133 3 1926.993483 643.3377 E3 ubiquitin-protein ligase ZNF598 OS=Homo sapiens OX=9606 GN=ZNF598 PE=1 SV=1 5.4 2475.8 - 697003 - - - 1.1982 - 2.669 0.427 - 164.1 1 2 0 0.0023 20 0 0 0 9.99E+07 1.35E+07 - - - 5.6816 1 221125_WJC_METTL3_EV_vs_WT_F06.14134.14134.2 9.71E-11 20/30 K.AVHNSVAAQLTGVAGH.- sp|Q9NUD5|ZCHC3_HUMAN 1 1530.7903 - 83330 14134 2 1530.788785 766.4024 Zinc finger CCHC domain-containing protein 3 OS=Homo sapiens OX=9606 GN=ZCCHC3 PE=1 SV=2 6.96 2475.9 - 665208 - - - -0.9825 - 4.494 0.664 - 1210.5 1 2 0 -0.0015 16 0 0 0 - - - - - 7.6394 0.9747 221125_WJC_METTL3_EV_vs_WT_F06.14135.14135.3 0.0582 14/56 K.EVLPALENNKEQIQK.L sp|Q9UHV9|PFD2_HUMAN 1 1751.9418 0.69 83331 14135 3 1751.936648 584.9879 Prefoldin subunit 2 OS=Homo sapiens OX=9606 GN=PFDN2 PE=1 SV=1 4.79 2476.1 - 570333 - - - -2.9202 - 2.419 0.192 - 228.3 1 2 1 -0.0051 15 0 0 0 6.82E+07 9.88E+07 - - - 2.9842 0.9997 221125_WJC_METTL3_EV_vs_WT_F06.14136.14136.3 9.16E-05 Dec-64 K.ILHSYVPEEIRDGNQVR.V sp|Q96CB9|NSUN4_HUMAN 1 2024.0439 0.98 83332 14136 3 2024.045039 675.6886 5-methylcytosine rRNA methyltransferase NSUN4 OS=Homo sapiens OX=9606 GN=NSUN4 PE=1 SV=2 5.45 2476.2 - 493799 - - - 0.544 - 2.249 0.452 - 161.5 1 2 1 0.0011 17 0 0 0 4.54E+06 4.65E+06 - - - 5.6266 0.9979 221125_WJC_METTL3_EV_vs_WT_F06.14141.14141.3 0.0352 Dec-48 K.VSDQKPLGSWSVK.Q "sp|Q9H8H0|NOL11_HUMAN,tr|J3QLQ6|J3QLQ6_HUMAN" 2 1429.7565 1.16 83335 14141 3 1429.75884 477.5928 Nucleolar protein 11 OS=Homo sapiens OX=9606 GN=NOL11 PE=1 SV=1 8.56 2476.8 - 2.24E+06 - - - 1.6164 - 1.848 0.259 - 140.8 1 2 0 0.0023 13 0 0 0 3.29E+07 2.83E+07 - - - 3.092 0.9992 221125_WJC_METTL3_EV_vs_WT_F06.14143.14143.3 0.000282 Nov-60 R.TSIIAAANPVGGHYNK.A "sp|Q9UJA3|MCM8_HUMAN,tr|A0A494C100|A0A494C100_HUMAN" 2 1611.8369 0.6 83337 14143 3 1611.832749 538.2862 DNA helicase MCM8 OS=Homo sapiens OX=9606 GN=MCM8 PE=1 SV=2 8.29 2476.9 - 1.21E+06 - - - -2.5784 - 2.188 0.336 - 101.9 1 2 0 -0.0042 16 0 0 0 2.09E+07 3.50E+07 - - - 4.294 1 221125_WJC_METTL3_EV_vs_WT_F06.14145.14145.2 1.74E-09 14/30 A.SSLVSGLNSSASEPAK[136.11].E "sp|Q86U44|MTA70_HUMAN,tr|F5H6D8|F5H6D8_HUMAN,tr|H0YFV6|H0YFV6_HUMAN,tr|B4DTN4|B4DTN4_HUMAN" 4 1540.7824 0.001 83339 14145 2 1540.77953 771.3985 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 5.72 2477.2 - 629469 - - - -1.8731 - 3.028 0.602 - 465 1 1 0 -0.0029 16 0 0 0 0.00E+00 1.36E+07 - - - 6.2103 1 221125_WJC_METTL3_EV_vs_WT_F06.14148.14148.3 0.000389 15/48 R.IQFK[136.11]PDDGISPER[166.11].A sp|Q96I24|FUBP3_HUMAN 1 1518.7797 1.93 83341 14148 3 1518.780844 507.2672 Far upstream element-binding protein 3 OS=Homo sapiens OX=9606 GN=FUBP3 PE=1 SV=2 4.56 2477.5 - 1.73E+07 - - - 0.7348 - 2.783 0.531 - 299.2 1 2 0 0.0011 13 0 0 0 5.95E+08 3.09E+08 - - - 7.2349 0.963 221125_WJC_METTL3_EV_vs_WT_F06.14153.14153.3 0.00166 13/56 K.EVLPALENNK[136.11]EQIQK[136.11].L sp|Q9UHV9|PFD2_HUMAN 1 1767.9702 0.76 83345 14153 3 1768.971457 590.3307 Prefoldin subunit 2 OS=Homo sapiens OX=9606 GN=PFDN2 PE=1 SV=1 4.79 2478 - 1.49E+06 - - - 566.3518 - 2.154 0.364 - 168.6 1 2 1 1.0013 15 0 0 0 9.48E+07 1.25E+08 - - - 4.3231 0.9999 221125_WJC_METTL3_EV_vs_WT_F06.14156.14156.3 6.25E-05 14/64 K.IFIKPNAQKPLPQALSK.E sp|Q01780|EXOSX_HUMAN 1 1892.1248 1.38 83348 14156 3 1892.125704 631.7155 Exosome component 10 OS=Homo sapiens OX=9606 GN=EXOSC10 PE=1 SV=2 10.3 2478.3 - 738819 - - - 0.5021 - 2.291 0.385 - 134.9 1 2 0 0.0009 17 0 0 0 1.87E+07 1.35E+07 - - - 4.9264 1 221125_WJC_METTL3_EV_vs_WT_F06.14163.14163.4 0.00013 15/96 K.IFIKPNAQKPLPQALSK.E sp|Q01780|EXOSX_HUMAN 1 1892.1248 1.05 83353 14163 4 1892.126475 474.0385 Exosome component 10 OS=Homo sapiens OX=9606 GN=EXOSC10 PE=1 SV=2 10.3 2479.2 - 3.11E+06 - - - 0.9096 - 2.758 0.498 - 162.8 1 2 0 0.0017 17 0 0 0 4.98E+07 4.76E+07 - - - 3.9123 0.9999 221125_WJC_METTL3_EV_vs_WT_F06.14165.14165.4 0.000231 17/78 R.TYGWGHNELRPIAR.K sp|O60476|MA1A2_HUMAN 1 1668.8485 1.58 83355 14165 4 1668.849666 418.2194 "Mannosyl-oligosaccharide 1,2-alpha-mannosidase IB OS=Homo sapiens OX=9606 GN=MAN1A2 PE=1 SV=1" 8.44 2479.3 - 3.20E+06 - - - 0.7149 - 2.465 0.449 - 237.5 1 2 0 0.0012 14 0 0 0 4.27E+07 2.71E+07 - - - 3.4621 0.9999 221125_WJC_METTL3_EV_vs_WT_F06.14168.14168.3 1.61E-07 13/52 R.TYGWGHNELRPIAR.K sp|O60476|MA1A2_HUMAN 1 1668.8485 1.78 83358 14168 3 1668.848808 557.2901 "Mannosyl-oligosaccharide 1,2-alpha-mannosidase IB OS=Homo sapiens OX=9606 GN=MAN1A2 PE=1 SV=1" 8.44 2479.5 - 1.64E+06 - - - 0.2007 - 2.112 0.477 - 183.3 1 2 0 0.0003 14 0 0 0 2.73E+07 1.53E+07 - - - 5.8448 0.9999 221125_WJC_METTL3_EV_vs_WT_F06.14169.14169.2 1.16E-08 19/26 K.VLHFDQVTENTTGK.A sp|P29508|SPB3_HUMAN 1 1587.7893 999 83359 14169 2 1587.788271 794.9019 Serpin B3 OS=Homo sapiens OX=9606 GN=SERPINB3 PE=1 SV=2 5.32 2479.6 - 1.22E+06 - - - -0.6393 - 3.383 0.489 - 1116.5 1 2 0 -0.001 14 0 0 0 2.19E+07 0.00E+00 - - - 5.7109 1 221125_WJC_METTL3_EV_vs_WT_F06.14178.14178.4 8.53E-05 16/78 R.TYGWGHNELR[166.11]PIAR[166.11].K sp|O60476|MA1A2_HUMAN 1 1688.865 1.56 83366 14178 4 1688.864145 423.2235 "Mannosyl-oligosaccharide 1,2-alpha-mannosidase IB OS=Homo sapiens OX=9606 GN=MAN1A2 PE=1 SV=1" 8.44 2480.9 - 4.38E+06 - - - -0.514 - 2.333 0.502 - 215.2 1 2 0 -0.0009 14 0 0 0 4.26E+07 2.73E+07 - - - 3.9035 1 221125_WJC_METTL3_EV_vs_WT_F06.14179.14179.3 1.87E-08 16/56 K.FTNTQITEHYSTC[160.03]IK.L "sp|Q15003|CND2_HUMAN,tr|C9J470|C9J470_HUMAN,tr|C9JZP1|C9JZP1_HUMAN,tr|E9PHA2|E9PHA2_HUMAN" 4 1841.8618 1.34 83367 14179 3 1841.861087 614.9612 Condensin complex subunit 2 OS=Homo sapiens OX=9606 GN=NCAPH PE=1 SV=3 6.74 2480.9 - 2.33E+06 - - - -0.3866 - 3.256 0.48 - 360.3 1 2 0 -0.0007 15 0 0 0 2.54E+07 1.90E+07 - - - 6.9717 0.9999 221125_WJC_METTL3_EV_vs_WT_F06.14180.14180.3 0.000105 Dec-52 R.TYGWGHNELR[166.11]PIAR[166.11].K sp|O60476|MA1A2_HUMAN 1 1688.865 2.72 83368 14180 3 1688.865029 563.9623 "Mannosyl-oligosaccharide 1,2-alpha-mannosidase IB OS=Homo sapiens OX=9606 GN=MAN1A2 PE=1 SV=1" 8.44 2481 - 2.40E+06 - - - 0.0095 - 1.74 0.482 - 149.7 1 2 0 0 14 0 0 0 4.53E+07 1.67E+07 - - - 5.3858 0.9998 221125_WJC_METTL3_EV_vs_WT_F06.14182.14182.3 2.18E-06 13/52 K.GSITISAEEIK[136.11]DNR[166.11].V "sp|O75131|CPNE3_HUMAN,tr|E5RHZ0|E5RHZ0_HUMAN,tr|A0A087WXR6|A0A087WXR6_HUMAN,tr|A0A087WYQ3|A0A087WYQ3_HUMAN,tr|H0YB26|H0YB26_HUMAN" 5 1549.8067 6.92 83370 14182 3 1549.808027 517.6095 Copine-3 OS=Homo sapiens OX=9606 GN=CPNE3 PE=1 SV=1 4.68 2481.1 - 1.93E+06 - - - 0.8749 - 2.799 0.427 - 245 1 2 1 0.0014 14 0 0 0 1.32E+08 1.90E+07 - - - 6.0356 0.9999 221125_WJC_METTL3_EV_vs_WT_F06.14188.14188.2 6.38E-10 Oct-34 K.ELSQNTDESGLNDEAIAK.Q "sp|P35251|RFC1_HUMAN,tr|A0A1W2PP02|A0A1W2PP02_HUMAN" 2 1932.8912 1.12 83376 14188 2 1932.893582 967.4529 Replication factor C subunit 1 OS=Homo sapiens OX=9606 GN=RFC1 PE=1 SV=4 3.83 2481.8 - 283245 - - - 1.2091 - 2.752 0.538 - 291 1 2 0 0.0023 18 0 0 0 2.29E+06 2.05E+06 - - - 5.5028 1 221125_WJC_METTL3_EV_vs_WT_F06.14200.14200.3 0.000612 13/36 K.KSDVETIFSK.Y "sp|Q9UKM9|RALY_HUMAN,tr|Q5QPM2|Q5QPM2_HUMAN,tr|Q5QPM1|Q5QPM1_HUMAN,tr|Q5QPL9|Q5QPL9_HUMAN" 4 1152.6027 1.15 83387 14200 3 1152.601394 385.2082 RNA-binding protein Raly OS=Homo sapiens OX=9606 GN=RALY PE=1 SV=1 6.07 2482.7 - 869172 - - - -1.0932 - 2.436 0.483 - 324.5 1 2 0 -0.0013 10 0 0 0 3.50E+07 3.04E+07 - - - 6.5249 0.9998 221125_WJC_METTL3_EV_vs_WT_F06.14201.14201.3 0.00139 Oct-36 R.K[136.11]ESYSIYVYK[136.11].V "sp|Q8N257|H2B3B_HUMAN,sp|P33778|H2B1B_HUMAN,sp|Q6DN03|H2B2C_HUMAN,sp|P23527|H2B1O_HUMAN,sp|Q6DRA6|H2B2D_HUMAN,sp|Q16778|H2B2E_HUMAN,sp|P06899|H2B1J_HUMAN" 7 1294.678 1.12 83388 14201 3 1294.676943 432.5666 Histone H2B type 3-B OS=Homo sapiens OX=9606 GN=H2BU1 PE=1 SV=3 8.38 2482.9 - 861784 - - - -0.8195 - 1.967 0.354 - 138.5 1 2 0 -0.0011 10 0 0 0 7.85E+06 7.03E+06 - - - 4.4622 0.9951 221125_WJC_METTL3_EV_vs_WT_F06.14207.14207.3 1.04E-05 19/60 Q.SIAAHLDNQVPVESPR.A "sp|P51398|RT29_HUMAN,tr|V9GY11|V9GY11_HUMAN,tr|V9GYJ9|V9GYJ9_HUMAN,tr|V9GYL4|V9GYL4_HUMAN,tr|V9GYL9|V9GYL9_HUMAN" 5 1731.8904 1.35 83392 14207 3 1731.890543 578.3041 "28S ribosomal protein S29, mitochondrial OS=Homo sapiens OX=9606 GN=DAP3 PE=1 SV=1" 5.3 2483.6 - 3.63E+06 - - - 0.0843 - 2.831 0.427 - 387 1 1 0 0.0001 16 0 0 0 9.76E+07 7.23E+07 - - - 5.9707 0.9999 221125_WJC_METTL3_EV_vs_WT_F06.14209.14209.3 0.000288 13/36 K.K[136.11]SDVETIFSK[136.11].Y "sp|Q9UKM9|RALY_HUMAN,tr|Q5QPM2|Q5QPM2_HUMAN,tr|Q5QPM1|Q5QPM1_HUMAN,tr|Q5QPL9|Q5QPL9_HUMAN" 4 1168.6311 1.15 83394 14209 3 1168.629132 390.551 RNA-binding protein Raly OS=Homo sapiens OX=9606 GN=RALY PE=1 SV=1 6.07 2483.7 - 1.69E+06 - - - -1.6447 - 2.404 0.448 - 330.8 1 2 0 -0.0019 10 0 0 0 3.50E+07 3.04E+07 - - - 6.0958 0.9995 221125_WJC_METTL3_EV_vs_WT_F06.14210.14210.3 0.00122 13/40 K.QKDPQDILEVK.E "sp|Q7L590|MCM10_HUMAN,tr|Q5T670|Q5T670_HUMAN" 2 1311.7034 1.85 83395 14210 3 1311.703264 438.2418 Protein MCM10 homolog OS=Homo sapiens OX=9606 GN=MCM10 PE=1 SV=2 4.56 2483.8 - 1.57E+06 - - - -0.1273 - 2.395 0.359 - 289.3 1 2 1 -0.0002 11 0 0 0 2.07E+07 1.12E+07 - - - 5.0236 0.9999 221125_WJC_METTL3_EV_vs_WT_F06.14211.14211.3 2.22E-06 15/40 K.QK[136.11]DPQDILEVK[136.11].E "sp|Q7L590|MCM10_HUMAN,tr|Q5T670|Q5T670_HUMAN" 2 1327.7318 1.91 83396 14211 3 1327.731109 443.5846 Protein MCM10 homolog OS=Homo sapiens OX=9606 GN=MCM10 PE=1 SV=2 4.56 2483.9 - 1.30E+06 - - - -0.5438 - 2.654 0.466 - 389.9 1 2 1 -0.0007 11 0 0 0 2.13E+07 1.12E+07 - - - 6.5081 1 221125_WJC_METTL3_EV_vs_WT_F06.14213.14213.2 2.97E-08 16/28 R.TSQVVEQDVPEEVDR.A "sp|Q9Y6X8|ZHX2_HUMAN,tr|H0YKA3|H0YKA3_HUMAN" 2 1728.8166 4.57 83398 14213 2 1728.823957 865.4156 Zinc fingers and homeoboxes protein 2 OS=Homo sapiens OX=9606 GN=ZHX2 PE=1 SV=1 3.83 2484.1 - 1.11E+06 - - - 4.2422 - 3.232 0.526 - 844.8 1 2 0 0.0073 15 0 0 0 1.20E+07 2.62E+06 - - - 5.8079 0.9978 221125_WJC_METTL3_EV_vs_WT_F06.14214.14214.4 0.0704 13/90 K.LLETHIHNQGLAAIEK[136.11].C "sp|Q13616|CUL1_HUMAN,tr|A0A590UJA0|A0A590UJA0_HUMAN,tr|A0A0C4DGX4|A0A0C4DGX4_HUMAN,tr|A0A590UJ21|A0A590UJ21_HUMAN,tr|A0A590UJ50|A0A590UJ50_HUMAN,tr|A0A590UJR3|A0A590UJR3_HUMAN,tr|A0A590UJ56|A0A590UJ56_HUMAN,tr|A0A590UK34|A0A590UK34_HUMAN" 8 1793.9879 0.62 83399 14214 4 1793.985474 449.5043 Cullin-1 OS=Homo sapiens OX=9606 GN=CUL1 PE=1 SV=2 6 2484.2 - 1.05E+06 - - - -1.3707 - 1.892 0.262 - 105.3 1 2 0 -0.0025 16 0 0 0 4.01E+06 6.50E+06 - - - 1.7304 1 221125_WJC_METTL3_EV_vs_WT_F06.14218.14218.2 3.35E-11 19/30 R.EAATQAQQTLGSTIDK.A "sp|P47897|SYQ_HUMAN,tr|F2Z2V6|F2Z2V6_HUMAN,tr|C9J165|C9J165_HUMAN,tr|A0A0U1RQT0|A0A0U1RQT0_HUMAN,tr|A0A0U1RQM8|A0A0U1RQM8_HUMAN,tr|A0A0U1RQU2|A0A0U1RQU2_HUMAN" 6 1660.8268 0.82 83403 14218 2 1660.824093 831.4207 Glutamine--tRNA ligase OS=Homo sapiens OX=9606 GN=QARS1 PE=1 SV=1 4.37 2484.7 - 537865 - - - -1.6263 - 3.326 0.635 - 1075.2 1 2 0 -0.0027 16 0 0 0 7.98E+07 9.72E+07 - - - 6.6849 0.9981 221125_WJC_METTL3_EV_vs_WT_F06.14224.14224.3 8.88E-06 15/60 Q.SIAAHLDNQVPVESPR[166.11].A "sp|P51398|RT29_HUMAN,tr|V9GY11|V9GY11_HUMAN,tr|V9GYJ9|V9GYJ9_HUMAN,tr|V9GYL4|V9GYL4_HUMAN,tr|V9GYL9|V9GYL9_HUMAN" 5 1741.8987 1.35 83407 14224 3 1741.896573 581.6402 "28S ribosomal protein S29, mitochondrial OS=Homo sapiens OX=9606 GN=DAP3 PE=1 SV=1" 5.3 2485.4 - 3.96E+06 - - - -1.2021 - 2.976 0.541 - 216 1 1 0 -0.0021 16 0 0 0 9.76E+07 7.23E+07 - - - 7.3693 0.9811 221125_WJC_METTL3_EV_vs_WT_F06.14225.14225.2 0.0173 12-Sep F.GDHIHWR[166.11].T "sp|O95881|TXD12_HUMAN,tr|V9GY50|V9GY50_HUMAN,tr|V9GYV4|V9GYV4_HUMAN" 3 929.4496 1.35 83408 14225 2 929.448854 465.7321 Thioredoxin domain-containing protein 12 OS=Homo sapiens OX=9606 GN=TXNDC12 PE=1 SV=1 6.92 2485.5 - 1.92E+06 - - - -0.7521 - 1.716 0.386 - 431.6 1 1 0 -0.0007 7 0 0 0 7.10E+07 5.26E+07 - - - 3.6028 1 221125_WJC_METTL3_EV_vs_WT_F06.14226.14226.2 3.72E-10 19/30 R.EAATQAQQTLGSTIDK[136.11].A "sp|P47897|SYQ_HUMAN,tr|F2Z2V6|F2Z2V6_HUMAN,tr|C9J165|C9J165_HUMAN,tr|A0A0U1RQT0|A0A0U1RQT0_HUMAN,tr|A0A0U1RQM8|A0A0U1RQM8_HUMAN,tr|A0A0U1RQU2|A0A0U1RQU2_HUMAN" 6 1668.841 1.23 83409 14226 2 1668.840595 835.4278 Glutamine--tRNA ligase OS=Homo sapiens OX=9606 GN=QARS1 PE=1 SV=1 4.37 2485.6 - 1.56E+06 - - - -0.2391 - 3.811 0.627 - 1505 1 2 0 -0.0004 16 0 0 0 7.31E+07 5.94E+07 - - - 6.9612 0.9997 221125_WJC_METTL3_EV_vs_WT_F06.14227.14227.3 0.000605 13/56 K.GVIVDK[136.11]DFSHPQMPK[136.11].K "sp|P48643|TCPE_HUMAN,tr|E9PCA1|E9PCA1_HUMAN,tr|B7ZAR1|B7ZAR1_HUMAN,tr|E7ENZ3|E7ENZ3_HUMAN" 4 1712.8891 0.61 83410 14227 3 1712.890055 571.9703 T-complex protein 1 subunit epsilon OS=Homo sapiens OX=9606 GN=CCT5 PE=1 SV=1 6.75 2485.7 - 1.30E+06 - - - 0.571 - 2.391 0.434 - 164.3 1 2 1 0.001 15 0 0 0 6.47E+08 1.06E+09 - - - 5.653 0.9996 221125_WJC_METTL3_EV_vs_WT_F06.14228.14228.3 0.000656 Dec-48 R.EK[136.11]EAVSYYNALEK[136.11].A "sp|Q96EA4|SPDLY_HUMAN,tr|D6RC83|D6RC83_HUMAN,tr|H0YBG5|H0YBG5_HUMAN" 3 1558.785 0.05 83411 14228 3 1558.784094 520.6023 Protein Spindly OS=Homo sapiens OX=9606 GN=SPDL1 PE=1 SV=2 4.79 2485.8 - 1.29E+06 - - - -0.5742 - 2.463 0.38 - 122.4 1 2 1 -0.0009 13 0 0 0 8.66E+05 1.63E+07 - - - 5.2203 1 221125_WJC_METTL3_EV_vs_WT_F06.14229.14229.3 5.03E-07 22/52 K.NRPFMGSISQQNIR.S "sp|Q9NWS0|PIHD1_HUMAN,tr|M0QXD5|M0QXD5_HUMAN,tr|M0R3A4|M0R3A4_HUMAN,tr|M0R2P8|M0R2P8_HUMAN,tr|M0QYA2|M0QYA2_HUMAN" 5 1646.8311 1.33 83412 14229 3 1646.828484 549.951 PIH1 domain-containing protein 1 OS=Homo sapiens OX=9606 GN=PIH1D1 PE=1 SV=1 12 2485.9 - 1.05E+06 - - - -1.5934 - 3.773 0.556 - 834.2 1 2 0 -0.0026 14 0 0 0 1.06E+09 7.93E+08 - - - 8.267 0.9998 221125_WJC_METTL3_EV_vs_WT_F06.14231.14231.4 1.42E-05 16/84 K.GVIVDKDFSHPQMPK.K "sp|P48643|TCPE_HUMAN,tr|E9PCA1|E9PCA1_HUMAN,tr|B7ZAR1|B7ZAR1_HUMAN,tr|E7ENZ3|E7ENZ3_HUMAN" 4 1696.8607 0.56 83414 14231 4 1696.863654 425.2224 T-complex protein 1 subunit epsilon OS=Homo sapiens OX=9606 GN=CCT5 PE=1 SV=1 6.75 2486.2 - 1.00E+06 - - - 1.7544 - 2.824 0.517 - 128 1 2 1 0.003 15 0 0 0 7.43E+08 1.32E+09 - - - 4.0966 1 221125_WJC_METTL3_EV_vs_WT_F06.14235.14235.3 9.35E-07 13/56 K.FTNTQITEHYSTC[160.03]IK[136.11].L "sp|Q15003|CND2_HUMAN,tr|C9J470|C9J470_HUMAN,tr|C9JZP1|C9JZP1_HUMAN,tr|E9PHA2|E9PHA2_HUMAN" 4 1849.876 1.34 83417 14235 3 1849.875728 617.6326 Condensin complex subunit 2 OS=Homo sapiens OX=9606 GN=NCAPH PE=1 SV=3 6.74 2486.6 - 512805 - - - -0.1465 - 2.577 0.456 - 153.2 1 2 0 -0.0003 15 0 0 0 2.54E+07 1.90E+07 - - - 6.094 0.9997 221125_WJC_METTL3_EV_vs_WT_F06.14236.14236.3 0.00134 Nov-52 R.TYSLGSALRPSTSR.S "sp|P08670|VIME_HUMAN,tr|B0YJC4|B0YJC4_HUMAN,tr|A0A1B0GVG8|A0A1B0GVG8_HUMAN,tr|A0A1B0GTT5|A0A1B0GTT5_HUMAN" 4 1494.7791 1.21 83418 14236 3 1494.778441 499.267 Vimentin OS=Homo sapiens OX=9606 GN=VIM PE=1 SV=4 10.83 2486.7 - 3.73E+06 - - - -0.4114 - 1.634 0.404 - 118.5 1 2 0 -0.0006 14 0 0 0 7.49E+07 6.19E+07 - - - 4.349 0.9996 221125_WJC_METTL3_EV_vs_WT_F06.14238.14238.3 0.00243 Nov-52 R.TYSLGSALR[166.11]PSTSR[166.11].S "sp|P08670|VIME_HUMAN,tr|B0YJC4|B0YJC4_HUMAN,tr|A0A1B0GVG8|A0A1B0GVG8_HUMAN,tr|A0A1B0GTT5|A0A1B0GTT5_HUMAN" 4 1514.7956 1.71 83420 14238 3 1514.79518 505.9391 Vimentin OS=Homo sapiens OX=9606 GN=VIM PE=1 SV=4 10.83 2486.8 - 3.12E+06 - - - -0.2746 - 1.631 0.37 - 118 1 2 0 -0.0004 14 0 0 0 2.46E+10 1.43E+10 - - - 3.9651 0.9997 221125_WJC_METTL3_EV_vs_WT_F06.14239.14239.4 3.28E-06 Dec-84 K.GVIVDK[136.11]DFSHPQMPK[136.11].K "sp|P48643|TCPE_HUMAN,tr|E9PCA1|E9PCA1_HUMAN,tr|B7ZAR1|B7ZAR1_HUMAN,tr|E7ENZ3|E7ENZ3_HUMAN" 4 1712.8891 0.56 83421 14239 4 1712.888054 429.2295 T-complex protein 1 subunit epsilon OS=Homo sapiens OX=9606 GN=CCT5 PE=1 SV=1 6.75 2486.9 - 2.74E+06 - - - -0.5972 - 2.523 0.446 - 70.8 1 2 1 -0.001 15 0 0 0 7.45E+08 1.32E+09 - - - 3.4388 0.9978 221125_WJC_METTL3_EV_vs_WT_F06.14240.14240.3 0.00129 13/52 R.QEEELQAKDEELLK.V sp|P35580|MYH10_HUMAN 1 1700.8469 0.78 83422 14240 3 1700.840807 567.9562 Myosin-10 OS=Homo sapiens OX=9606 GN=MYH10 PE=1 SV=3 4.14 2486.9 - 1.72E+06 - - - -3.5588 - 2.14 0.428 - 187.8 1 2 1 -0.0061 14 0 0 0 6.21E+07 8.00E+07 - - - 5.332 1 221125_WJC_METTL3_EV_vs_WT_F06.14243.14243.3 3.88E-06 Oct-44 R.K[136.11]YTGEDFDEDLR[166.11].T "sp|Q14204|DYHC1_HUMAN,tr|A0A7P0T8N2|A0A7P0T8N2_HUMAN,tr|A0A7P0T9C4|A0A7P0T9C4_HUMAN,tr|A0A7P0TBJ7|A0A7P0TBJ7_HUMAN,tr|A0A7P0T9K2|A0A7P0T9K2_HUMAN,tr|A0A2R8Y706|A0A2R8Y706_HUMAN,tr|A0A7P0T916|A0A7P0T916_HUMAN,tr|A0A7P0TB75|A0A7P0TB75_HUMAN,tr|A0A7P0T8W5|A0A7P0T8W5_HUMAN,tr|A0A7P0TAF3|A0A7P0TAF3_HUMAN,tr|A0A7P0T9F1|A0A7P0T9F1_HUMAN,tr|A0A7P0TAW9|A0A7P0TAW9_HUMAN,tr|A0A7P0TA13|A0A7P0TA13_HUMAN,tr|A0A7P0T7V5|A0A7P0T7V5_HUMAN,tr|A0A7P0T9R4|A0A7P0T9R4_HUMAN,tr|A0A2R8Y5T0|A0A2R8Y5T0_HUMAN,tr|A0A2R8YFZ7|A0A2R8YFZ7_HUMAN,tr|A0A7P0T825|A0A7P0T825_HUMAN,tr|A0A2R8Y6H2|A0A2R8Y6H2_HUMAN,tr|A0A7P0TAM4|A0A7P0TAM4_HUMAN" 20 1504.6801 0.94 83425 14243 3 1504.67984 502.5673 Cytoplasmic dynein 1 heavy chain 1 OS=Homo sapiens OX=9606 GN=DYNC1H1 PE=1 SV=5 4.11 2487.2 - 1.18E+06 - - - -0.1549 - 2.098 0.5 - 127 1 2 0 -0.0002 12 0 0 0 1.10E+07 1.17E+07 - - - 6.1683 0.9296 221125_WJC_METTL3_EV_vs_WT_F06.14244.14244.3 0.0023 Nov-68 K.YVHYEIDAC[160.03]MDSEAPGSK.D "sp|Q86U44|MTA70_HUMAN,tr|H0YFV6|H0YFV6_HUMAN" 2 2070.8663 -1 83426 14244 3 2070.848467 691.296 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 4.31 2487.3 - 1.03E+06 - - - -8.6075 - 1.69 0.347 - 58 1 2 0 -0.0178 18 0 0 0 0.00E+00 0.00E+00 - - - 3.7104 0.9994 221125_WJC_METTL3_EV_vs_WT_F06.14245.14245.2 0.0022 22-Dec R.ALEEANADLEVK.L "sp|P02533|K1C14_HUMAN,sp|P08779|K1C16_HUMAN,sp|P19012|K1C15_HUMAN,sp|P13646|K1C13_HUMAN,tr|K7EMD9|K7EMD9_HUMAN,tr|K7ERE3|K7ERE3_HUMAN" 6 1300.6511 999 83427 14245 2 1300.647601 651.3328 "Keratin, type I cytoskeletal 14 OS=Homo sapiens OX=9606 GN=KRT14 PE=1 SV=4" 4 2487.5 - 763919 - - - -2.6602 - 2.38 0.404 - 454.1 1 2 0 -0.0035 12 0 0 0 2.01E+07 0.00E+00 - - - 4.3053 0.9228 221125_WJC_METTL3_EV_vs_WT_F06.14248.14248.4 0.00645 Oct-96 K.TAWLVIVDDDTLISISR[166.11].L sp|Q6Y288|B3GLT_HUMAN 1 1926.0338 0.04 83428 14248 4 1926.02483 482.5157 "Beta-1,3-glucosyltransferase OS=Homo sapiens OX=9606 GN=B3GLCT PE=1 SV=2" 3.93 2487.9 - 6.75E+06 - - - -4.6385 - 2.366 0.197 - 46.9 1 2 0 -0.0089 17 0 0 0 5.36E+06 1.33E+08 - - - 1.2372 0.9962 221125_WJC_METTL3_EV_vs_WT_F06.14249.14249.3 0.0112 Nov-36 R.KQGLEQFINK.V sp|O60493|SNX3_HUMAN 1 1203.6612 1.24 83429 14249 3 1203.659985 402.2277 Sorting nexin-3 OS=Homo sapiens OX=9606 GN=SNX3 PE=1 SV=3 8.59 2487.9 - 1.36E+06 - - - -0.9862 - 1.907 0.178 - 171.1 1 2 0 -0.0012 10 0 0 0 1.39E+07 1.12E+07 - - - 2.4094 1 221125_WJC_METTL3_EV_vs_WT_F06.14251.14251.3 1.08E-08 19/72 K.IVSSSDVGHDEYSTQSLVK.K "sp|Q01082|SPTB2_HUMAN,tr|A0A087WUZ3|A0A087WUZ3_HUMAN" 2 2049.9855 1.7 83431 14251 3 2049.984638 684.3358 "Spectrin beta chain, non-erythrocytic 1 OS=Homo sapiens OX=9606 GN=SPTBN1 PE=1 SV=2" 4.54 2488.1 - 1.45E+06 - - - -0.4102 - 2.924 0.599 - 151 1 2 0 -0.0008 19 0 0 0 1.21E+08 7.14E+07 - - - 7.8541 0.9912 221125_WJC_METTL3_EV_vs_WT_F06.14253.14253.2 0.13 26-Jun R.TYSLGSALRPSTSR.S "sp|P08670|VIME_HUMAN,tr|B0YJC4|B0YJC4_HUMAN,tr|A0A1B0GVG8|A0A1B0GVG8_HUMAN,tr|A0A1B0GTT5|A0A1B0GTT5_HUMAN" 4 1494.7791 1.38 83433 14253 2 1494.777093 748.3968 Vimentin OS=Homo sapiens OX=9606 GN=VIM PE=1 SV=4 10.83 2488.4 - 634638 - - - -1.3132 - 1.142 0.248 - 24.5 4 2 0 -0.002 14 0 0 0 1.06E+07 7.69E+06 - - - 0.9364 0.9472 221125_WJC_METTL3_EV_vs_WT_F06.14255.14255.2 1.78 26-May R.TYSLGSALR[166.11]PSTSR[166.11].S "sp|P08670|VIME_HUMAN,tr|B0YJC4|B0YJC4_HUMAN,tr|A0A1B0GVG8|A0A1B0GVG8_HUMAN,tr|A0A1B0GTT5|A0A1B0GTT5_HUMAN" 4 1514.7956 1.38 83435 14255 2 1514.796364 758.4051 Vimentin OS=Homo sapiens OX=9606 GN=VIM PE=1 SV=4 10.83 2488.6 - 491273 - - - 0.507 - 1.023 0.126 - 19.5 10 2 0 0.0008 14 0 0 0 1.06E+07 7.69E+06 - - - -0.4182 1 221125_WJC_METTL3_EV_vs_WT_F06.14258.14258.2 2.17E-09 16/32 K.TGIEQGSDAGYLC[160.03]ESQK[136.11].F "sp|P40939|ECHA_HUMAN,tr|A0A2R8YG21|A0A2R8YG21_HUMAN,tr|H0YFD6|H0YFD6_HUMAN,tr|A0A2R8Y4F5|A0A2R8Y4F5_HUMAN" 4 1849.8244 0.95 83436 14258 2 1849.819425 925.9195 "Trifunctional enzyme subunit alpha, mitochondrial OS=Homo sapiens OX=9606 GN=HADHA PE=1 SV=2" 4.14 2489.1 - 1.53E+06 - - - -2.6667 - 3.258 0.67 - 436.1 1 2 0 -0.0049 17 0 0 0 2.79E+07 2.93E+07 - - - 6.8919 1 221125_WJC_METTL3_EV_vs_WT_F06.14259.14259.2 5.98E-09 15/32 K.TGIEQGSDAGYLC[160.03]ESQK.F "sp|P40939|ECHA_HUMAN,tr|A0A2R8YG21|A0A2R8YG21_HUMAN,tr|H0YFD6|H0YFD6_HUMAN,tr|A0A2R8Y4F5|A0A2R8Y4F5_HUMAN" 4 1841.8102 0.95 83437 14259 2 1841.807668 921.9124 "Trifunctional enzyme subunit alpha, mitochondrial OS=Homo sapiens OX=9606 GN=HADHA PE=1 SV=2" 4.14 2489.2 - 1.29E+06 - - - -1.3519 - 3.48 0.679 - 739.2 1 2 0 -0.0025 17 0 0 0 2.79E+07 2.93E+07 - - - 7.1212 0.9999 221125_WJC_METTL3_EV_vs_WT_F06.14260.14260.3 0.00292 16/64 K.TGIEQGSDAGYLC[160.03]ESQK[136.11].F "sp|P40939|ECHA_HUMAN,tr|A0A2R8YG21|A0A2R8YG21_HUMAN,tr|H0YFD6|H0YFD6_HUMAN,tr|A0A2R8Y4F5|A0A2R8Y4F5_HUMAN" 4 1849.8244 0.61 83438 14260 3 1849.819602 617.6154 "Trifunctional enzyme subunit alpha, mitochondrial OS=Homo sapiens OX=9606 GN=HADHA PE=1 SV=2" 4.14 2489.3 - 1.08E+06 - - - -2.5711 - 2.788 0.522 - 195.8 1 2 0 -0.0048 17 0 0 0 7.84E+06 1.28E+07 - - - 6.9487 0.9733 221125_WJC_METTL3_EV_vs_WT_F06.14261.14261.4 0.136 Aug-72 R.QERPPVKPFILTR.N sp|P78318|IGBP1_HUMAN 1 1579.9198 0.83 83439 14261 4 1579.918542 395.9872 Immunoglobulin-binding protein 1 OS=Homo sapiens OX=9606 GN=IGBP1 PE=1 SV=1 10.84 2489.4 - 1.03E+06 - - - -0.826 - 1.771 0.16 - 52.3 1 2 0 -0.0013 13 0 0 0 7.34E+06 8.83E+06 - - - 0.8302 0.9998 221125_WJC_METTL3_EV_vs_WT_F06.14262.14262.3 3.59E-05 14/44 R.EK[136.11]DIEIDALSQK[136.11].C "sp|Q15643|TRIPB_HUMAN,tr|H0YJ97|H0YJ97_HUMAN" 2 1403.7479 1.27 83440 14262 3 1403.748615 468.9232 Thyroid receptor-interacting protein 11 OS=Homo sapiens OX=9606 GN=TRIP11 PE=1 SV=3 4.32 2489.5 - 876426 - - - 0.5272 - 2.66 0.435 - 409.8 1 2 1 0.0007 12 0 0 0 4.05E+08 3.18E+08 - - - 6.1014 0.9995 221125_WJC_METTL3_EV_vs_WT_F06.14264.14264.3 4.84E-05 16/64 K.TGIEQGSDAGYLC[160.03]ESQK.F "sp|P40939|ECHA_HUMAN,tr|A0A2R8YG21|A0A2R8YG21_HUMAN,tr|H0YFD6|H0YFD6_HUMAN,tr|A0A2R8Y4F5|A0A2R8Y4F5_HUMAN" 4 1841.8102 0.61 83442 14264 3 1841.8008 614.944 "Trifunctional enzyme subunit alpha, mitochondrial OS=Homo sapiens OX=9606 GN=HADHA PE=1 SV=2" 4.14 2489.8 - 732973 - - - -5.0809 - 2.465 0.518 - 102.6 1 2 0 -0.0094 17 0 0 0 7.84E+06 1.28E+07 - - - 6.5918 0.9992 221125_WJC_METTL3_EV_vs_WT_F06.14269.14269.3 0.0103 Nov-44 R.QSVEADINGLRR.V "sp|P13645|K1C10_HUMAN,sp|Q7Z3Y8|K1C27_HUMAN,sp|P13646|K1C13_HUMAN,tr|A0A1B0GVI3|A0A1B0GVI3_HUMAN,tr|K7EMD9|K7EMD9_HUMAN,tr|K7ERE3|K7ERE3_HUMAN" 6 1356.711 149122.59 83445 14269 3 1356.71074 453.2443 "Keratin, type I cytoskeletal 10 OS=Homo sapiens OX=9606 GN=KRT10 PE=1 SV=6" 6.07 2490.3 - 3.18E+07 - - - -0.174 - 1.853 0.287 - 201.9 1 2 0 -0.0002 12 0 0 0 4.83E+10 3.24E+05 - - - 3.4494 1 221125_WJC_METTL3_EV_vs_WT_F06.14270.14270.2 5.02E-06 15/26 K.VQALEEANNDLENK.L sp|P35527|K1C9_HUMAN 1 1585.7584 999 83446 14270 2 1585.758088 793.8865 "Keratin, type I cytoskeletal 9 OS=Homo sapiens OX=9606 GN=KRT9 PE=1 SV=3" 4 2490.4 - 1.21E+07 - - - -0.1841 - 2.994 0.618 - 754.6 1 2 0 -0.0003 14 0 0 0 1.28E+09 0.00E+00 - - - 6.3573 0.9988 221125_WJC_METTL3_EV_vs_WT_F06.14271.14271.2 0.0467 22-Dec R.QSVEADINGLRR.V "sp|P13645|K1C10_HUMAN,sp|Q7Z3Y8|K1C27_HUMAN,sp|P13646|K1C13_HUMAN,tr|A0A1B0GVI3|A0A1B0GVI3_HUMAN,tr|K7EMD9|K7EMD9_HUMAN,tr|K7ERE3|K7ERE3_HUMAN" 6 1356.711 -1 83447 14271 2 1356.710646 679.3628 "Keratin, type I cytoskeletal 10 OS=Homo sapiens OX=9606 GN=KRT10 PE=1 SV=6" 6.07 2490.4 - 3.23E+06 - - - -0.2432 - 1.701 0.242 - 191.3 1 2 0 -0.0003 12 0 0 0 0.00E+00 0.00E+00 - - - 2.226 0.9172 221125_WJC_METTL3_EV_vs_WT_F06.14277.14277.3 3.55E-08 23/76 R.AEGPVAVVVNGHTEGPAPAR[166.11].S sp|Q86UK7|ZN598_HUMAN 1 1936.9994 7.47 83453 14277 3 1937.985566 646.6738 E3 ubiquitin-protein ligase ZNF598 OS=Homo sapiens OX=9606 GN=ZNF598 PE=1 SV=1 5.4 2491.1 - 735429 - - - 509.0977 - 3.856 0.477 - 770.1 1 2 0 0.9861 20 0 0 0 1.05E+08 1.40E+07 - - - 6.8592 1 221125_WJC_METTL3_EV_vs_WT_F06.14286.14286.3 1.03E-05 14/52 K.NR[166.11]PFMGSISQQNIR[166.11].S "sp|Q9NWS0|PIHD1_HUMAN,tr|M0QXD5|M0QXD5_HUMAN,tr|M0R3A4|M0R3A4_HUMAN,tr|M0R2P8|M0R2P8_HUMAN,tr|M0QYA2|M0QYA2_HUMAN" 5 1666.8476 1.33 83460 14286 3 1666.847424 556.6232 PIH1 domain-containing protein 1 OS=Homo sapiens OX=9606 GN=PIH1D1 PE=1 SV=1 12 2492.1 - 6.54E+06 - - - -0.1344 - 3.006 0.523 - 304.1 1 2 0 -0.0002 14 0 0 0 1.06E+09 7.95E+08 - - - 7.2958 0.9999 221125_WJC_METTL3_EV_vs_WT_F06.14287.14287.3 1.94E-06 13/44 R.EKDIEIDALSQK.C "sp|Q15643|TRIPB_HUMAN,tr|H0YJ97|H0YJ97_HUMAN" 2 1387.7195 1.28 83461 14287 3 1387.718275 463.5804 Thyroid receptor-interacting protein 11 OS=Homo sapiens OX=9606 GN=TRIP11 PE=1 SV=3 4.32 2492.2 - 6.70E+06 - - - -0.8647 - 2.614 0.51 - 349.5 1 2 1 -0.0012 12 0 0 0 4.05E+08 3.18E+08 - - - 6.8891 1 221125_WJC_METTL3_EV_vs_WT_F06.14288.14288.3 0.000117 19/72 K.IVSSSDVGHDEYSTQSLVK[136.11].K "sp|Q01082|SPTB2_HUMAN,tr|A0A087WUZ3|A0A087WUZ3_HUMAN" 2 2057.9997 1.69 83462 14288 3 2057.99681 687.0072 "Spectrin beta chain, non-erythrocytic 1 OS=Homo sapiens OX=9606 GN=SPTBN1 PE=1 SV=2" 4.54 2492.2 - 4.94E+06 - - - -1.3941 - 3.457 0.558 - 280.5 1 2 0 -0.0029 19 0 0 0 1.21E+08 7.14E+07 - - - 7.8078 0.9597 221125_WJC_METTL3_EV_vs_WT_F06.14293.14293.3 0.109 Aug-48 R.QKDYETATLSEIK.A "sp|P12814|ACTN1_HUMAN,tr|A0A804HK61|A0A804HK61_HUMAN,tr|H7C5W8|H7C5W8_HUMAN,tr|A0A804HJU8|A0A804HJU8_HUMAN,tr|A0A804HIN7|A0A804HIN7_HUMAN,tr|H9KV75|H9KV75_HUMAN,tr|A0A804HLF4|A0A804HLF4_HUMAN,tr|A0A7I2V4Y4|A0A7I2V4Y4_HUMAN,tr|A0A804HII9|A0A804HII9_HUMAN,tr|A0A804HL31|A0A804HL31_HUMAN,tr|A0A804HKE2|A0A804HKE2_HUMAN,tr|A0A804HLD0|A0A804HLD0_HUMAN" 12 1524.7672 2.34 83467 14293 3 1524.761689 509.263 Alpha-actinin-1 OS=Homo sapiens OX=9606 GN=ACTN1 PE=1 SV=2 4.68 2492.6 - 1.28E+06 - - - -3.5842 - 1.579 0.288 - 76.4 1 2 1 -0.0055 13 0 0 0 3.81E+07 1.63E+07 - - - 2.9879 0.9999 221125_WJC_METTL3_EV_vs_WT_F06.14294.14294.2 4.48E-07 15/26 R.TSQENSPALLGVQK.G "sp|Q8IWZ3|ANKH1_HUMAN,tr|E9PDP5|E9PDP5_HUMAN,tr|H3BLS9|H3BLS9_HUMAN,tr|H7C2F5|H7C2F5_HUMAN" 4 1470.7678 1.35 83468 14294 2 1470.769622 736.3912 Ankyrin repeat and KH domain-containing protein 1 OS=Homo sapiens OX=9606 GN=ANKHD1 PE=1 SV=1 5.66 2492.7 - 780207 - - - 1.2239 - 2.585 0.557 - 923.4 1 2 0 0.0018 14 0 0 0 9.95E+07 7.37E+07 - - - 5.5377 0.9639 221125_WJC_METTL3_EV_vs_WT_F06.14295.14295.3 0.0381 Dec-52 R.TYSLGSALR[166.11]PSTSR.S "sp|P08670|VIME_HUMAN,tr|B0YJC4|B0YJC4_HUMAN,tr|A0A1B0GVG8|A0A1B0GVG8_HUMAN,tr|A0A1B0GTT5|A0A1B0GTT5_HUMAN" 4 1504.7873 - 83469 14295 3 1504.792968 502.6031 Vimentin OS=Homo sapiens OX=9606 GN=VIM PE=1 SV=4 10.83 2492.8 - 751674 - - - 3.7494 - 1.354 0.253 - 125.7 1 2 0 0.0056 14 0 0 0 - - - - - 2.1645 1 221125_WJC_METTL3_EV_vs_WT_F06.14296.14296.2 2.94E-07 15/22 R.EK[136.11]DIEIDALSQK[136.11].C "sp|Q15643|TRIPB_HUMAN,tr|H0YJ97|H0YJ97_HUMAN" 2 1403.7479 1.43 83470 14296 2 1403.750257 702.8812 Thyroid receptor-interacting protein 11 OS=Homo sapiens OX=9606 GN=TRIP11 PE=1 SV=3 4.32 2493 - 700800 - - - 1.6969 - 2.7 0.584 - 670.1 1 2 1 0.0024 12 0 0 0 1.11E+08 7.75E+07 - - - 5.9671 1 221125_WJC_METTL3_EV_vs_WT_F06.14297.14297.2 2.01E-13 17/32 R.SPYTVTVGQAC[160.03]NPSAC[160.03]R[166.11].A "sp|P21333|FLNA_HUMAN,tr|A0A669KBC6|A0A669KBC6_HUMAN,tr|A0A7P0NMY4|A0A7P0NMY4_HUMAN,tr|Q60FE5|Q60FE5_HUMAN,tr|F8WE98|F8WE98_HUMAN" 5 1876.8435 1.35 83471 14297 2 1876.841082 939.429 Filamin-A OS=Homo sapiens OX=9606 GN=FLNA PE=1 SV=4 7.79 2493.1 - 666030 - - - -1.308 - 3.543 0.718 - 756.7 1 2 0 -0.0025 17 0 0 0 1.33E+07 9.84E+06 - - - 7.4534 0.9994 221125_WJC_METTL3_EV_vs_WT_F06.14311.14311.3 0.000108 14/52 K.LLVPAAEGEDSLKK.M "sp|Q96PU8|QKI_HUMAN,tr|F5GYM3|F5GYM3_HUMAN,tr|F5GXS8|F5GXS8_HUMAN,tr|H0YG47|H0YG47_HUMAN,tr|H0YGD6|H0YGD6_HUMAN" 5 1468.8137 0.94 83483 14311 3 1468.820411 490.6118 Protein quaking OS=Homo sapiens OX=9606 GN=QKI PE=1 SV=1 4.68 2494.5 - 913922 - - - 4.5622 - 2.163 0.486 - 215.2 1 2 0 0.0067 14 0 0 0 1.73E+07 1.85E+07 - - - 6.0068 0.9996 221125_WJC_METTL3_EV_vs_WT_F06.14312.14312.3 0.000606 Dec-40 K.VGYELKDEIER.K sp|Q8WWY3|PRP31_HUMAN 1 1349.6827 0.62 83484 14312 3 1349.68203 450.9015 U4\U6 small nuclear ribonucleoprotein Prp31 OS=Homo sapiens OX=9606 GN=PRPF31 PE=1 SV=2 4.41 2494.6 - 513355 - - - -0.4934 - 2.206 0.406 - 197.5 1 2 1 -0.0007 11 0 0 0 4.55E+06 7.38E+06 - - - 5.3139 0.9483 221125_WJC_METTL3_EV_vs_WT_F06.14316.14316.2 0.000952 13/22 Y.SLGSALR[166.11]PSTSR[166.11].S "sp|P08670|VIME_HUMAN,tr|B0YJC4|B0YJC4_HUMAN,tr|A0A1B0GVG8|A0A1B0GVG8_HUMAN,tr|A0A1B0GTT5|A0A1B0GTT5_HUMAN" 4 1250.6846 2.05 83486 14316 2 1250.682177 626.3496 Vimentin OS=Homo sapiens OX=9606 GN=VIM PE=1 SV=4 12 2495.1 - 4.94E+06 - - - -1.9277 - 1.742 0.377 - 156.2 2 1 0 -0.0024 12 0 0 0 1.11E+09 5.40E+08 - - - 3.1507 1 221125_WJC_METTL3_EV_vs_WT_F06.14324.14324.2 6.07E-12 17/26 K.NRPFMGSISQQNIR.S "sp|Q9NWS0|PIHD1_HUMAN,tr|M0QXD5|M0QXD5_HUMAN,tr|M0R3A4|M0R3A4_HUMAN,tr|M0R2P8|M0R2P8_HUMAN,tr|M0QYA2|M0QYA2_HUMAN" 5 1646.8311 1.71 83491 14324 2 1646.82442 824.4228 PIH1 domain-containing protein 1 OS=Homo sapiens OX=9606 GN=PIH1D1 PE=1 SV=1 12 2496.2 - 1.91E+06 - - - -4.0611 - 3.42 0.657 - 237.7 1 2 0 -0.0067 14 0 0 0 1.66E+08 9.72E+07 - - - 6.9772 1 221125_WJC_METTL3_EV_vs_WT_F06.14325.14325.3 1.71E-07 14/40 K.ESENVVC[160.03]HFYR.D "sp|O14530|TXND9_HUMAN,tr|F8WCJ3|F8WCJ3_HUMAN,tr|B8ZZX4|B8ZZX4_HUMAN" 3 1438.6299 4.53 83492 14325 3 1438.631251 480.5506 Thioredoxin domain-containing protein 9 OS=Homo sapiens OX=9606 GN=TXNDC9 PE=1 SV=2 5.4 2496.3 - 2.08E+06 - - - 0.905 - 2.631 0.551 - 429.7 1 2 0 0.0013 11 0 0 0 3.45E+07 7.62E+06 - - - 7.4309 1 221125_WJC_METTL3_EV_vs_WT_F06.14326.14326.2 1.45E-07 16/26 R.TSQENSPALLGVQK[136.11].G "sp|Q8IWZ3|ANKH1_HUMAN,tr|E9PDP5|E9PDP5_HUMAN,tr|H3BLS9|H3BLS9_HUMAN,tr|H7C2F5|H7C2F5_HUMAN" 4 1478.782 1.36 83493 14326 2 1478.778571 740.3983 Ankyrin repeat and KH domain-containing protein 1 OS=Homo sapiens OX=9606 GN=ANKHD1 PE=1 SV=1 5.66 2496.4 - 3.03E+06 - - - -2.3337 - 2.708 0.57 - 1014.8 1 2 0 -0.0035 14 0 0 0 9.91E+07 7.29E+07 - - - 5.7499 0.9944 221125_WJC_METTL3_EV_vs_WT_F06.14327.14327.2 5.37E-08 22-Dec R.R[166.11]AEQDSTTVAAF.A "sp|Q86U44|MTA70_HUMAN,tr|F5H6D8|F5H6D8_HUMAN,tr|H0YFV6|H0YFV6_HUMAN,tr|B4DTN4|B4DTN4_HUMAN" 4 1304.6236 0 83494 14327 2 1304.622598 653.3191 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 4.37 2496.6 - 2.00E+06 - - - -0.7788 - 2.351 0.582 - 498.6 1 1 0 -0.001 12 0 0 0 1.30E+06 6.03E+08 - - - 5.5886 0.9996 221125_WJC_METTL3_EV_vs_WT_F06.14328.14328.2 5.72E-06 14/26 K.NR[166.11]PFMGSISQQNIR[166.11].S "sp|Q9NWS0|PIHD1_HUMAN,tr|M0QXD5|M0QXD5_HUMAN,tr|M0R3A4|M0R3A4_HUMAN,tr|M0R2P8|M0R2P8_HUMAN,tr|M0QYA2|M0QYA2_HUMAN" 5 1666.8476 1.71 83495 14328 2 1666.842879 834.4311 PIH1 domain-containing protein 1 OS=Homo sapiens OX=9606 GN=PIH1D1 PE=1 SV=1 12 2496.7 - 1.93E+06 - - - -2.8611 - 2.439 0.547 - 118.2 1 2 0 -0.0048 14 0 0 0 1.66E+08 9.72E+07 - - - 5.317 1 221125_WJC_METTL3_EV_vs_WT_F06.14349.14349.3 3.30E-06 Dec-52 R.AGVNTVTTLVENKK.A "sp|P62424|RL7A_HUMAN,tr|Q5T8U2|Q5T8U2_HUMAN,tr|Q5T8U3|Q5T8U3_HUMAN" 3 1472.8199 0.88 83507 14349 3 1472.822412 491.9472 60S ribosomal protein L7a OS=Homo sapiens OX=9606 GN=RPL7A PE=1 SV=2 8.64 2499.2 - 5.08E+06 - - - 1.7341 - 2.563 0.507 - 161.2 1 2 0 0.0026 14 0 0 0 1.96E+08 2.22E+08 - - - 6.6931 1 221125_WJC_METTL3_EV_vs_WT_F06.14356.14356.3 3.73E-08 20/60 R.EANFTVSSMHGDMPQK.E "sp|P38919|IF4A3_HUMAN,tr|I3L3H2|I3L3H2_HUMAN" 2 1777.7764 1.89 83510 14356 3 1777.771523 593.5994 Eukaryotic initiation factor 4A-III OS=Homo sapiens OX=9606 GN=EIF4A3 PE=1 SV=4 5.32 2500.1 - 3.15E+06 - - - -2.718 - 3.394 0.577 - 444.6 1 2 0 -0.0048 16 0 0 0 1.39E+08 7.39E+07 - - - 8.1072 1 221125_WJC_METTL3_EV_vs_WT_F06.14364.14364.3 5.15E-08 21/56 K.GVIVDKDFSHPQMPK.K "sp|P48643|TCPE_HUMAN,tr|E9PCA1|E9PCA1_HUMAN,tr|B7ZAR1|B7ZAR1_HUMAN,tr|E7ENZ3|E7ENZ3_HUMAN" 4 1696.8607 0.61 83512 14364 3 1696.857735 566.6275 T-complex protein 1 subunit epsilon OS=Homo sapiens OX=9606 GN=CCT5 PE=1 SV=1 6.75 2501.2 - 1.32E+07 - - - -1.7338 - 3.873 0.603 - 501.4 1 2 1 -0.0029 15 0 0 0 6.46E+08 1.06E+09 - - - 8.7952 1 221125_WJC_METTL3_EV_vs_WT_F06.14365.14365.3 1.05E-07 20/60 R.EANFTVSSMHGDMPQK[136.11].E "sp|P38919|IF4A3_HUMAN,tr|I3L3H2|I3L3H2_HUMAN" 2 1785.7906 1.89 83513 14365 3 1785.790992 596.2708 Eukaryotic initiation factor 4A-III OS=Homo sapiens OX=9606 GN=EIF4A3 PE=1 SV=4 5.32 2501.3 - 1.87E+06 - - - 0.2447 - 3.381 0.533 - 746 1 2 0 0.0004 16 0 0 0 1.39E+08 7.39E+07 - - - 7.608 0.9965 221125_WJC_METTL3_EV_vs_WT_F06.14369.14369.3 9.75E-05 Nov-48 R.EK[136.11]NGVYISEENFR[166.11].V "sp|P52732|KIF11_HUMAN,tr|A0A7I2YQY4|A0A7I2YQY4_HUMAN,tr|A0A7I2V3A9|A0A7I2V3A9_HUMAN,tr|A0A7I2V3V3|A0A7I2V3V3_HUMAN" 4 1601.7805 5.66 83515 14369 3 1601.774899 534.9341 Kinesin-like protein KIF11 OS=Homo sapiens OX=9606 GN=KIF11 PE=1 SV=2 4.79 2501.8 - 6.45E+06 - - - -3.4693 - 2.181 0.376 - 135.4 1 2 1 -0.0056 13 0 0 0 1.96E+09 3.47E+08 - - - 4.8447 0.9949 221125_WJC_METTL3_EV_vs_WT_F06.14370.14370.3 1.88E-05 14/48 K.HPELNISEEGITK.S "sp|P17480|UBF1_HUMAN,tr|E9PKP7|E9PKP7_HUMAN" 2 1465.7413 0.62 83516 14370 3 1465.737559 489.5877 Nucleolar transcription factor 1 OS=Homo sapiens OX=9606 GN=UBTF PE=1 SV=1 4.75 2501.9 - 3.25E+06 - - - -2.5339 - 2.518 0.163 - 400.5 1 2 0 -0.0037 13 0 0 0 1.30E+08 2.11E+08 - - - 2.86 1 221125_WJC_METTL3_EV_vs_WT_F06.14374.14374.3 7.56E-07 22/52 R.LHISQLQHENSILK.G "sp|Q14203|DCTN1_HUMAN,tr|A0A804CDA6|A0A804CDA6_HUMAN,tr|E7EX90|E7EX90_HUMAN,tr|A0A7P0Z4C3|A0A7P0Z4C3_HUMAN,tr|E7EWF7|E7EWF7_HUMAN" 5 1658.9104 1.78 83518 14374 3 1658.907079 553.9774 Dynactin subunit 1 OS=Homo sapiens OX=9606 GN=DCTN1 PE=1 SV=3 6.92 2502.4 - 5.86E+06 - - - -2.0043 - 3.897 0.549 - 492.1 1 2 0 -0.0033 14 0 0 0 5.34E+08 2.99E+08 - - - 8.2747 0.9896 221125_WJC_METTL3_EV_vs_WT_F06.14375.14375.2 1.28E-07 15/26 R.R[166.11]AEQDSTTVAAFAS.S "sp|Q86U44|MTA70_HUMAN,tr|F5H6D8|F5H6D8_HUMAN,tr|H0YFV6|H0YFV6_HUMAN,tr|B4DTN4|B4DTN4_HUMAN" 4 1462.6928 0.02 83519 14375 2 1462.691152 732.3537 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 4.37 2502.5 - 3.56E+06 - - - -1.0966 - 2.131 0.496 - 421 1 1 0 -0.0016 14 0 0 0 2.08E+07 1.16E+09 - - - 4.6026 0.9992 221125_WJC_METTL3_EV_vs_WT_F06.14381.14381.4 0.00393 13/78 R.LHISQLQHENSILK[136.11].G "sp|Q14203|DCTN1_HUMAN,tr|A0A804CDA6|A0A804CDA6_HUMAN,tr|E7EX90|E7EX90_HUMAN,tr|A0A7P0Z4C3|A0A7P0Z4C3_HUMAN,tr|E7EWF7|E7EWF7_HUMAN" 5 1666.9246 1.78 83522 14381 4 1666.920294 417.7384 Dynactin subunit 1 OS=Homo sapiens OX=9606 GN=DCTN1 PE=1 SV=3 6.92 2503.3 - 3.81E+06 - - - -2.5856 - 2.158 0.343 - 121 1 2 0 -0.0043 14 0 0 0 3.28E+08 1.84E+08 - - - 2.4902 0.9994 221125_WJC_METTL3_EV_vs_WT_F06.14383.14383.4 0.0028 Dec-78 R.LHISQLQHENSILK.G "sp|Q14203|DCTN1_HUMAN,tr|A0A804CDA6|A0A804CDA6_HUMAN,tr|E7EX90|E7EX90_HUMAN,tr|A0A7P0Z4C3|A0A7P0Z4C3_HUMAN,tr|E7EWF7|E7EWF7_HUMAN" 5 1658.9104 1.78 83524 14383 4 1658.90735 415.7349 Dynactin subunit 1 OS=Homo sapiens OX=9606 GN=DCTN1 PE=1 SV=3 6.92 2503.4 - 5.56E+06 - - - -1.841 - 2.489 0.331 - 111.2 1 2 0 -0.0031 14 0 0 0 3.28E+08 1.84E+08 - - - 2.4381 0.9998 221125_WJC_METTL3_EV_vs_WT_F06.14388.14388.3 0.00122 13/52 R.QFQDAGHFDAENIK.K "sp|Q13813|SPTN1_HUMAN,tr|A0A0D9SF54|A0A0D9SF54_HUMAN,tr|A0A0D9SGF6|A0A0D9SGF6_HUMAN" 3 1618.7376 1.33 83527 14388 3 1618.73466 540.5865 "Spectrin alpha chain, non-erythrocytic 1 OS=Homo sapiens OX=9606 GN=SPTAN1 PE=1 SV=3" 4.54 2504.1 - 2.33E+06 - - - -1.807 - 2.247 0.398 - 164.5 1 2 0 -0.0029 14 0 0 0 5.19E+07 3.89E+07 - - - 5.128 0.9972 221125_WJC_METTL3_EV_vs_WT_F06.14389.14389.3 0.000218 14/52 K.NQTSLLGEPPK[136.11]EIR[166.11].L sp|Q9HCJ3|RAVR2_HUMAN 1 1598.8747 1.25 83528 14389 3 1598.86863 533.9655 Ribonucleoprotein PTB-binding 2 OS=Homo sapiens OX=9606 GN=RAVER2 PE=1 SV=2 6.14 2504.1 - 1.43E+07 - - - -3.7908 - 2.411 0.395 - 235.2 1 2 1 -0.0061 14 0 0 0 2.18E+08 1.74E+08 - - - 5.2809 0.9999 221125_WJC_METTL3_EV_vs_WT_F06.14395.14395.3 2.30E-05 16/52 R.LHISQLQHENSILK[136.11].G "sp|Q14203|DCTN1_HUMAN,tr|A0A804CDA6|A0A804CDA6_HUMAN,tr|E7EX90|E7EX90_HUMAN,tr|A0A7P0Z4C3|A0A7P0Z4C3_HUMAN,tr|E7EWF7|E7EWF7_HUMAN" 5 1666.9246 1.78 83532 14395 3 1666.922467 556.6488 Dynactin subunit 1 OS=Homo sapiens OX=9606 GN=DCTN1 PE=1 SV=3 6.92 2504.9 - 9.81E+06 - - - -1.282 - 2.53 0.414 - 262.7 1 2 0 -0.0021 14 0 0 0 5.34E+08 2.99E+08 - - - 5.6219 0.9956 221125_WJC_METTL3_EV_vs_WT_F06.14397.14397.2 4.29E-09 14/24 R.EK[136.11]NGVYISEENFR[166.11].V "sp|P52732|KIF11_HUMAN,tr|A0A7I2YQY4|A0A7I2YQY4_HUMAN,tr|A0A7I2V3A9|A0A7I2V3A9_HUMAN,tr|A0A7I2V3V3|A0A7I2V3V3_HUMAN" 4 1601.7805 14.93 83533 14397 2 1601.785001 801.8975 Kinesin-like protein KIF11 OS=Homo sapiens OX=9606 GN=KIF11 PE=1 SV=2 4.79 2505.1 - 2.32E+06 - - - 2.8375 - 2.747 0.5 - 650.5 1 2 1 0.0045 13 0 0 0 6.49E+08 4.35E+07 - - - 5.3261 1 221125_WJC_METTL3_EV_vs_WT_F06.14402.14402.2 0.000148 19/26 R.LHISQLQHENSILK.G "sp|Q14203|DCTN1_HUMAN,tr|A0A804CDA6|A0A804CDA6_HUMAN,tr|E7EX90|E7EX90_HUMAN,tr|A0A7P0Z4C3|A0A7P0Z4C3_HUMAN,tr|E7EWF7|E7EWF7_HUMAN" 5 1658.9104 2.26 83538 14402 2 1658.91067 830.4625 Dynactin subunit 1 OS=Homo sapiens OX=9606 GN=DCTN1 PE=1 SV=3 6.92 2505.6 - 1.03E+06 - - - 0.1603 - 3.521 0.573 - 887.1 1 2 0 0.0003 14 0 0 0 2.76E+07 1.22E+07 - - - 6.4319 0.997 221125_WJC_METTL3_EV_vs_WT_F06.14409.14409.3 0.000329 14/48 R.HLDTLTEHYDIPK[136.11].V "sp|Q9Y421|FA32A_HUMAN,tr|K7EIY1|K7EIY1_HUMAN" 2 1588.7977 1.21 83542 14409 3 1589.798171 530.6065 Protein FAM32A OS=Homo sapiens OX=9606 GN=FAM32A PE=1 SV=2 5.21 2506.4 - 4.23E+06 - - - 629.7208 - 2.097 0.479 - 199.2 1 2 0 1.0005 13 0 0 0 9.70E+07 8.02E+07 - - - 5.611 1 221125_WJC_METTL3_EV_vs_WT_F06.14415.14415.2 2.47E-10 20/38 K.IGGDAGTSLNSNDYGYGGQK[136.11].R "sp|Q96AE4|FUBP1_HUMAN,tr|E9PEB5|E9PEB5_HUMAN,tr|C9JSZ1|C9JSZ1_HUMAN" 3 1980.8905 1.48 83546 14415 2 1980.88787 991.4525 Far upstream element-binding protein 1 OS=Homo sapiens OX=9606 GN=FUBP1 PE=1 SV=3 4.21 2507.2 - 1.05E+06 - - - -1.309 - 3.52 0.7 - 1216.2 1 2 0 -0.0026 20 0 0 0 2.27E+07 1.53E+07 - - - 7.3044 0.9999 221125_WJC_METTL3_EV_vs_WT_F06.14416.14416.3 0.00245 Dec-48 K.HPELNISEEGITK[136.11].S "sp|P17480|UBF1_HUMAN,tr|E9PKP7|E9PKP7_HUMAN" 2 1473.7555 0.62 83547 14416 3 1473.755511 492.2591 Nucleolar transcription factor 1 OS=Homo sapiens OX=9606 GN=UBTF PE=1 SV=1 4.75 2507.2 - 3.26E+06 - - - 0.0258 - 2.254 0.422 - 281.2 1 2 0 0 13 0 0 0 1.33E+08 2.14E+08 - - - 5.4484 1 221125_WJC_METTL3_EV_vs_WT_F06.14418.14418.2 6.28E-08 18/26 R.LHISQLQHENSILK[136.11].G "sp|Q14203|DCTN1_HUMAN,tr|A0A804CDA6|A0A804CDA6_HUMAN,tr|E7EX90|E7EX90_HUMAN,tr|A0A7P0Z4C3|A0A7P0Z4C3_HUMAN,tr|E7EWF7|E7EWF7_HUMAN" 5 1666.9246 2.26 83549 14418 2 1666.920166 834.4696 Dynactin subunit 1 OS=Homo sapiens OX=9606 GN=DCTN1 PE=1 SV=3 6.92 2507.5 - 656104 - - - -2.6624 - 3.288 0.593 - 774.4 1 2 0 -0.0044 14 0 0 0 2.76E+07 1.22E+07 - - - 6.4065 0.9969 221125_WJC_METTL3_EV_vs_WT_F06.14421.14421.3 0.0455 Oct-52 K.NQTSLLGEPPKEIR.L sp|Q9HCJ3|RAVR2_HUMAN 1 1580.8522 1.24 83550 14421 3 1580.850645 527.958 Ribonucleoprotein PTB-binding 2 OS=Homo sapiens OX=9606 GN=RAVER2 PE=1 SV=2 6.14 2507.9 - 4.86E+07 - - - -0.9969 - 2.036 0.283 - 108.1 1 2 1 -0.0016 14 0 0 0 2.16E+08 1.74E+08 - - - 3.5842 0.9988 221125_WJC_METTL3_EV_vs_WT_F06.14422.14422.4 7.92E-05 17/84 R.AELRDDPIISTHLAK.L sp|O00231|PSD11_HUMAN 1 1677.905 0.63 83551 14422 4 1677.903719 420.4835 26S proteasome non-ATPase regulatory subunit 11 OS=Homo sapiens OX=9606 GN=PSMD11 PE=1 SV=3 5.38 2508 - 2.03E+06 - - - -0.7539 - 2.289 0.352 - 299.5 1 2 1 -0.0013 15 0 0 0 4.45E+07 7.11E+07 - - - 2.5858 0.9997 221125_WJC_METTL3_EV_vs_WT_F06.14425.14425.3 0.000203 17/56 R.AELRDDPIISTHLAK.L sp|O00231|PSD11_HUMAN 1 1677.905 0.57 83554 14425 3 1677.905713 560.3089 26S proteasome non-ATPase regulatory subunit 11 OS=Homo sapiens OX=9606 GN=PSMD11 PE=1 SV=3 5.38 2508.2 - 963594 - - - 0.4345 - 2.688 0.4 - 354.2 1 2 1 0.0007 15 0 0 0 2.68E+07 4.68E+07 - - - 5.5795 0.9999 221125_WJC_METTL3_EV_vs_WT_F06.14436.14436.3 4.78E-07 16/68 K.K[136.11]VLQSEGEAVDPEANVIK[136.11].Q "sp|Q8IWI9|MGAP_HUMAN,tr|H3BU53|H3BU53_HUMAN" 2 1941.039 5.86 83563 14436 3 1941.033383 648.0203 MAX gene-associated protein OS=Homo sapiens OX=9606 GN=MGA PE=1 SV=4 4.41 2509.5 - 605731 - - - -2.8794 - 3.235 0.516 - 278.9 1 2 0 -0.0056 18 0 0 0 1.48E+07 2.53E+06 - - - 7.2148 0.9989 221125_WJC_METTL3_EV_vs_WT_F06.14437.14437.2 1.68E-05 13/26 R.NALQQENHIIDGVK.V "sp|Q9GZT3|SLIRP_HUMAN,tr|H0YJW7|H0YJW7_HUMAN,tr|A0A087WUN7|A0A087WUN7_HUMAN,tr|G3V2S9|G3V2S9_HUMAN,tr|H0YJ40|H0YJ40_HUMAN,tr|G3V4X6|G3V4X6_HUMAN" 6 1577.8162 1.2 83564 14437 2 1577.809107 789.9154 "SRA stem-loop-interacting RNA-binding protein, mitochondrial OS=Homo sapiens OX=9606 GN=SLIRP PE=1 SV=1" 5.32 2509.6 - 431034 - - - -4.4758 - 2.876 0.538 - 503.5 1 2 0 -0.0071 14 0 0 0 1.75E+07 1.46E+07 - - - 5.6634 1 221125_WJC_METTL3_EV_vs_WT_F06.14441.14441.3 6.63E-09 21/64 K.QSAQLTALAAQQQAAGK.E sp|Q96A49|SYAP1_HUMAN 1 1683.8904 1.36 83566 14441 3 1683.891008 562.3041 Synapse-associated protein 1 OS=Homo sapiens OX=9606 GN=SYAP1 PE=1 SV=1 8.75 2510.1 - 2.77E+06 - - - 0.3629 - 3.866 0.506 - 887.3 1 2 0 0.0006 17 0 0 0 1.39E+08 1.02E+08 - - - 7.5973 1 221125_WJC_METTL3_EV_vs_WT_F06.14442.14442.2 3.12E-10 21/32 K.QSAQLTALAAQQQAAGK.E sp|Q96A49|SYAP1_HUMAN 1 1683.8904 1.35 83567 14442 2 1683.889808 842.9525 Synapse-associated protein 1 OS=Homo sapiens OX=9606 GN=SYAP1 PE=1 SV=1 8.75 2510.2 - 1.90E+06 - - - -0.3498 - 4.103 0.66 - 1729.2 1 2 0 -0.0006 17 0 0 0 9.78E+07 7.26E+07 - - - 7.3863 1 221125_WJC_METTL3_EV_vs_WT_F06.14445.14445.2 2.93E-15 20/38 K.IGGDAGTSLNSNDYGYGGQK.R "sp|Q96AE4|FUBP1_HUMAN,tr|E9PEB5|E9PEB5_HUMAN,tr|C9JSZ1|C9JSZ1_HUMAN" 3 1972.8763 1.48 83570 14445 2 1972.877297 987.4454 Far upstream element-binding protein 1 OS=Homo sapiens OX=9606 GN=FUBP1 PE=1 SV=3 4.21 2510.6 - 1.10E+06 - - - 0.5241 - 4.06 0.774 - 1314.8 1 2 0 0.001 20 0 0 0 2.27E+07 1.53E+07 - - - 8.2023 1 221125_WJC_METTL3_EV_vs_WT_F06.14446.14446.2 1.65E-09 17/26 K.C[160.03]PNPPVQENFDVNK.Y "sp|P05090|APOD_HUMAN,tr|F8WBT9|F8WBT9_HUMAN,tr|C9JF17|C9JF17_HUMAN,tr|C9JX71|C9JX71_HUMAN" 4 1656.7566 999 83571 14446 2 1656.756904 829.3856 Apolipoprotein D OS=Homo sapiens OX=9606 GN=APOD PE=1 SV=1 4.37 2510.7 - 1.01E+06 - - - 0.1799 - 2.705 0.61 - 1071.4 1 2 0 0.0003 14 0 0 0 1.61E+07 0.00E+00 - - - 6.0435 1 221125_WJC_METTL3_EV_vs_WT_F06.14455.14455.3 2.51E-06 14/52 R.NALQQENHIIDGVK.V "sp|Q9GZT3|SLIRP_HUMAN,tr|H0YJW7|H0YJW7_HUMAN,tr|A0A087WUN7|A0A087WUN7_HUMAN,tr|G3V2S9|G3V2S9_HUMAN,tr|H0YJ40|H0YJ40_HUMAN,tr|G3V4X6|G3V4X6_HUMAN" 6 1577.8162 1.23 83578 14455 3 1577.816343 526.946 "SRA stem-loop-interacting RNA-binding protein, mitochondrial OS=Homo sapiens OX=9606 GN=SLIRP PE=1 SV=1" 5.32 2511.9 - 1.60E+07 - - - 0.1103 - 2.634 0.514 - 263.6 1 2 0 0.0002 14 0 0 0 1.09E+08 8.90E+07 - - - 6.8444 1 221125_WJC_METTL3_EV_vs_WT_F06.14457.14457.3 1.07E-07 16/64 K.QSAQLTALAAQQQAAGK[136.11].E sp|Q96A49|SYAP1_HUMAN 1 1691.9046 1.36 83580 14457 3 1691.903786 564.9755 Synapse-associated protein 1 OS=Homo sapiens OX=9606 GN=SYAP1 PE=1 SV=1 8.75 2512 - 6.50E+06 - - - -0.4793 - 3.255 0.531 - 433.4 1 2 0 -0.0008 17 0 0 0 1.39E+08 1.02E+08 - - - 7.4414 0.9861 221125_WJC_METTL3_EV_vs_WT_F06.14458.14458.4 0.00126 Dec-60 K.IWHHTFYNELR[166.11].V "sp|Q6S8J3|POTEE_HUMAN,sp|P63261|ACTG_HUMAN,sp|P68133|ACTS_HUMAN,sp|Q9BYX7|ACTBM_HUMAN,sp|P68032|ACTC_HUMAN,sp|P60709|ACTB_HUMAN,sp|A5A3E0|POTEF_HUMAN,sp|P0CG38|POTEI_HUMAN,sp|P0CG39|POTEJ_HUMAN,tr|A0A804GS07|A0A804GS07_HUMAN,tr|I3L3I0|I3L3I0_HUMAN,tr|G5E9R0|G5E9R0_HUMAN,tr|E7EVS6|E7EVS6_HUMAN,tr|A0A6Q8PFE4|A0A6Q8PFE4_HUMAN,tr|J3KT65|J3KT65_HUMAN,tr|I3L3R2|I3L3R2_HUMAN,tr|K7EM38|K7EM38_HUMAN,tr|A0A6Q8PH58|A0A6Q8PH58_HUMAN,tr|I3L1U9|I3L1U9_HUMAN,tr|A0A804HKV3|A0A804HKV3_HUMAN,tr|A0A2R8Y793|A0A2R8Y793_HUMAN,tr|I3L4N8|I3L4N8_HUMAN,tr|C9JUM1|C9JUM1_HUMAN,tr|C9JZR7|C9JZR7_HUMAN,tr|A0A2R8YGF8|A0A2R8YGF8_HUMAN,tr|A6NL76|A6NL76_HUMAN" 26 1524.7502 0.3 83581 14458 4 1524.748947 382.1948 POTE ankyrin domain family member E OS=Homo sapiens OX=9606 GN=POTEE PE=2 SV=3 6.92 2512.1 - 4.45E+06 - - - -0.7903 - 1.79 0.184 - 98.8 1 2 0 -0.0012 11 0 0 0 7.68E+06 2.58E+07 - - - 1.0526 1 221125_WJC_METTL3_EV_vs_WT_F06.14459.14459.2 4.67E-09 16/32 K.QSAQLTALAAQQQAAGK[136.11].E sp|Q96A49|SYAP1_HUMAN 1 1691.9046 1.35 83582 14459 2 1691.902967 846.9596 Synapse-associated protein 1 OS=Homo sapiens OX=9606 GN=SYAP1 PE=1 SV=1 8.75 2512.1 - 3.78E+06 - - - -0.9634 - 3.287 0.65 - 1034.6 1 2 0 -0.0016 17 0 0 0 9.78E+07 7.26E+07 - - - 6.767 0.996 221125_WJC_METTL3_EV_vs_WT_F06.14460.14460.3 3.70E-06 13/40 K.GNEFEDYC[160.03]LK[136.11]R[166.11].E "sp|P26196|DDX6_HUMAN,tr|Q8IV96|Q8IV96_HUMAN" 2 1447.6521 0.63 83583 14460 3 1448.6521 483.558 Probable ATP-dependent RNA helicase DDX6 OS=Homo sapiens OX=9606 GN=DDX6 PE=1 SV=2 4.68 2512.2 - 2.73E+06 - - - 690.7848 - 2.05 0.481 - 183.7 1 2 0 1 11 0 0 0 2.57E+07 4.08E+07 - - - 5.6649 0.9999 221125_WJC_METTL3_EV_vs_WT_F06.14461.14461.3 0.000535 Oct-40 K.HGFTILNSMHK[136.11].Y sp|Q13207|TBX2_HUMAN 1 1291.6587 0.84 83584 14461 3 1291.658165 431.5602 T-box transcription factor TBX2 OS=Homo sapiens OX=9606 GN=TBX2 PE=1 SV=3 8.76 2512.2 - 2.53E+06 - - - -0.3956 - 1.743 0.43 - 137 1 2 0 -0.0005 11 0 0 0 2.09E+07 2.49E+07 - - - 4.9123 0.9999 221125_WJC_METTL3_EV_vs_WT_F06.14462.14462.3 0.00018 Dec-36 R.KDAEAWFNEK.S "sp|P13645|K1C10_HUMAN,sp|Q7Z3Y7|K1C28_HUMAN,tr|A0A1B0GVI3|A0A1B0GVI3_HUMAN" 3 1236.5775 624.89 83585 14462 3 1236.576888 413.1998 "Keratin, type I cytoskeletal 10 OS=Homo sapiens OX=9606 GN=KRT10 PE=1 SV=6" 4.68 2512.3 - 2.52E+06 - - - -0.4965 - 2.356 0.418 - 209 1 2 0 -0.0006 10 0 0 0 5.11E+08 8.18E+05 - - - 5.7028 1 221125_WJC_METTL3_EV_vs_WT_F06.14465.14465.2 4.65E-08 22/26 R.NALQQENHIIDGVK[136.11].V "sp|Q9GZT3|SLIRP_HUMAN,tr|H0YJW7|H0YJW7_HUMAN,tr|A0A087WUN7|A0A087WUN7_HUMAN,tr|G3V2S9|G3V2S9_HUMAN,tr|H0YJ40|H0YJ40_HUMAN,tr|G3V4X6|G3V4X6_HUMAN" 6 1585.8304 1.15 83588 14465 2 1585.830617 793.9225 "SRA stem-loop-interacting RNA-binding protein, mitochondrial OS=Homo sapiens OX=9606 GN=SLIRP PE=1 SV=1" 5.32 2512.5 - 1.44E+06 - - - 0.1564 - 4.143 0.642 - 2091.6 1 2 0 0.0002 14 0 0 0 1.50E+07 1.30E+07 - - - 7.3497 1 221125_WJC_METTL3_EV_vs_WT_F06.14467.14467.2 3.64E-10 17/30 R.ATSTATSGFAGAIGQK[136.11].L "sp|P51659|DHB4_HUMAN,tr|A0A2R8Y7L2|A0A2R8Y7L2_HUMAN,tr|A0A2R8YD50|A0A2R8YD50_HUMAN,tr|A0A804HIR1|A0A804HIR1_HUMAN,tr|E7ET17|E7ET17_HUMAN,tr|E7ER27|E7ER27_HUMAN,tr|E7EPL9|E7EPL9_HUMAN,tr|A0A804HKU2|A0A804HKU2_HUMAN,tr|A0A804HK65|A0A804HK65_HUMAN" 9 1474.7507 0.25 83590 14467 2 1474.748688 738.3826 Peroxisomal multifunctional enzyme type 2 OS=Homo sapiens OX=9606 GN=HSD17B4 PE=1 SV=3 8.8 2512.8 - 1.13E+06 - - - -1.3792 - 3.303 0.606 - 1298.3 1 2 0 -0.002 16 0 0 0 4.54E+06 1.82E+07 - - - 6.4538 1 221125_WJC_METTL3_EV_vs_WT_F06.14468.14468.2 2.31E-12 14/34 M.AYEPQGGSGYDYSYAGGR.G "sp|P61978|HNRPK_HUMAN,tr|S4R359|S4R359_HUMAN,tr|Q5T6W2|Q5T6W2_HUMAN" 3 1896.7915 1.28 83591 14468 2 1896.790756 949.403 Heterogeneous nuclear ribonucleoprotein K OS=Homo sapiens OX=9606 GN=HNRNPK PE=1 SV=1 4.37 2512.9 - 936030 - - - -0.377 - 2.915 0.796 - 552.1 1 1 0 -0.0007 18 0 0 0 8.14E+06 6.37E+06 - - - 7.5504 0.9998 221125_WJC_METTL3_EV_vs_WT_F06.14470.14470.2 1.37E-05 20-Dec K.IWHHTFYNELR[166.11].V "sp|Q6S8J3|POTEE_HUMAN,sp|P63261|ACTG_HUMAN,sp|P68133|ACTS_HUMAN,sp|Q9BYX7|ACTBM_HUMAN,sp|P68032|ACTC_HUMAN,sp|P60709|ACTB_HUMAN,sp|A5A3E0|POTEF_HUMAN,sp|P0CG38|POTEI_HUMAN,sp|P0CG39|POTEJ_HUMAN,tr|A0A804GS07|A0A804GS07_HUMAN,tr|I3L3I0|I3L3I0_HUMAN,tr|G5E9R0|G5E9R0_HUMAN,tr|E7EVS6|E7EVS6_HUMAN,tr|A0A6Q8PFE4|A0A6Q8PFE4_HUMAN,tr|J3KT65|J3KT65_HUMAN,tr|I3L3R2|I3L3R2_HUMAN,tr|K7EM38|K7EM38_HUMAN,tr|A0A6Q8PH58|A0A6Q8PH58_HUMAN,tr|I3L1U9|I3L1U9_HUMAN,tr|A0A804HKV3|A0A804HKV3_HUMAN,tr|A0A2R8Y793|A0A2R8Y793_HUMAN,tr|I3L4N8|I3L4N8_HUMAN,tr|C9JUM1|C9JUM1_HUMAN,tr|C9JZR7|C9JZR7_HUMAN,tr|A0A2R8YGF8|A0A2R8YGF8_HUMAN,tr|A6NL76|A6NL76_HUMAN" 26 1524.7502 0.54 83593 14470 2 1524.752235 763.3824 POTE ankyrin domain family member E OS=Homo sapiens OX=9606 GN=POTEE PE=2 SV=3 6.92 2513.2 - 572961 - - - 1.3661 - 2.207 0.508 - 463 1 2 0 0.0021 11 0 0 0 2.67E+06 4.91E+06 - - - 4.934 0.9998 221125_WJC_METTL3_EV_vs_WT_F06.14471.14471.2 0.000175 30-Oct K.SQLLAPPPPSAPPGNK.T "sp|P49750|YLPM1_HUMAN,tr|F8VU51|F8VU51_HUMAN" 2 1569.8515 999 83594 14471 2 1569.849646 785.933 YLP motif-containing protein 1 OS=Homo sapiens OX=9606 GN=YLPM1 PE=1 SV=4 8.47 2513.3 - 447759 - - - -1.1759 - 2.242 0.479 - 241.8 1 2 0 -0.0018 16 0 0 0 3.67E+06 0.00E+00 - - - 4.5633 0.9999 221125_WJC_METTL3_EV_vs_WT_F06.14476.14476.3 0.00016 Dec-40 K.IWHHTFYNELR.V "sp|Q6S8J3|POTEE_HUMAN,sp|P63261|ACTG_HUMAN,sp|P68133|ACTS_HUMAN,sp|Q9BYX7|ACTBM_HUMAN,sp|P68032|ACTC_HUMAN,sp|P60709|ACTB_HUMAN,sp|A5A3E0|POTEF_HUMAN,sp|P0CG38|POTEI_HUMAN,sp|P0CG39|POTEJ_HUMAN,tr|A0A804GS07|A0A804GS07_HUMAN,tr|I3L3I0|I3L3I0_HUMAN,tr|G5E9R0|G5E9R0_HUMAN,tr|E7EVS6|E7EVS6_HUMAN,tr|A0A6Q8PFE4|A0A6Q8PFE4_HUMAN,tr|J3KT65|J3KT65_HUMAN,tr|I3L3R2|I3L3R2_HUMAN,tr|K7EM38|K7EM38_HUMAN,tr|A0A6Q8PH58|A0A6Q8PH58_HUMAN,tr|I3L1U9|I3L1U9_HUMAN,tr|A0A804HKV3|A0A804HKV3_HUMAN,tr|A0A2R8Y793|A0A2R8Y793_HUMAN,tr|I3L4N8|I3L4N8_HUMAN,tr|C9JUM1|C9JUM1_HUMAN,tr|C9JZR7|C9JZR7_HUMAN,tr|A0A2R8YGF8|A0A2R8YGF8_HUMAN,tr|A6NL76|A6NL76_HUMAN" 26 1514.7419 0.64 83598 14476 3 1514.743141 505.9212 POTE ankyrin domain family member E OS=Homo sapiens OX=9606 GN=POTEE PE=2 SV=3 6.92 2513.8 - 2.01E+07 - - - 0.8312 - 2.203 0.439 - 213.1 1 2 0 0.0013 11 0 0 0 8.46E+07 1.32E+08 - - - 5.6778 0.9996 221125_WJC_METTL3_EV_vs_WT_F06.14477.14477.3 4.87E-06 Oct-48 K.SVEEGK[136.11]IDGIIDK[136.11].T sp|Q96A49|SYAP1_HUMAN 1 1417.7635 0.99 83599 14477 3 1417.763858 473.5951 Synapse-associated protein 1 OS=Homo sapiens OX=9606 GN=SYAP1 PE=1 SV=1 4.32 2513.8 - 5.99E+06 - - - 0.2349 - 2.014 0.444 - 77.2 1 2 1 0.0003 13 0 0 0 7.06E+08 7.12E+08 - - - 5.3883 1 221125_WJC_METTL3_EV_vs_WT_F06.14478.14478.3 1.24E-09 17/72 R.GVFAGTNTGPNNSNTTFQK.R "sp|Q9NYF8|BCLF1_HUMAN,tr|H0YF14|H0YF14_HUMAN" 2 1953.9181 2.79 83600 14478 3 1953.918606 652.3133 Bcl-2-associated transcription factor 1 OS=Homo sapiens OX=9606 GN=BCLAF1 PE=1 SV=2 8.75 2513.9 - 3.41E+06 - - - 0.2753 - 3.418 0.607 - 467.1 1 2 0 0.0005 19 0 0 0 2.12E+07 7.60E+06 - - - 8.3268 1 221125_WJC_METTL3_EV_vs_WT_F06.14480.14480.3 0.000217 14/40 K.GNEFEDYC[160.03]LKR.E "sp|P26196|DDX6_HUMAN,tr|Q8IV96|Q8IV96_HUMAN" 2 1429.6296 0.62 83602 14480 3 1429.630362 477.5505 Probable ATP-dependent RNA helicase DDX6 OS=Homo sapiens OX=9606 GN=DDX6 PE=1 SV=2 4.68 2514 - 2.69E+06 - - - 0.5232 - 2.57 0.505 - 419.4 1 2 0 0.0007 11 0 0 0 2.59E+07 4.19E+07 - - - 6.8515 0.9999 221125_WJC_METTL3_EV_vs_WT_F06.14481.14481.3 0.000258 Nov-48 R.IQFKPDDGISPER.A sp|Q96I24|FUBP3_HUMAN 1 1500.7573 5.87 83603 14481 3 1500.760022 501.2597 Far upstream element-binding protein 3 OS=Homo sapiens OX=9606 GN=FUBP3 PE=1 SV=2 4.56 2514 - 2.52E+06 - - - 1.8424 - 2.488 0.425 - 144.1 1 2 0 0.0028 13 0 0 0 4.55E+07 7.76E+06 - - - 5.7488 1 221125_WJC_METTL3_EV_vs_WT_F06.14483.14483.2 2.18E-12 18/36 R.GVFAGTNTGPNNSNTTFQK.R "sp|Q9NYF8|BCLF1_HUMAN,tr|H0YF14|H0YF14_HUMAN" 2 1953.9181 6.04 83605 14483 2 1953.920965 977.9663 Bcl-2-associated transcription factor 1 OS=Homo sapiens OX=9606 GN=BCLAF1 PE=1 SV=2 8.75 2514.2 - 1.80E+06 - - - 1.4827 - 3.875 0.737 - 1000.3 1 2 0 0.0029 19 0 0 0 2.07E+07 3.43E+06 - - - 7.8138 0.9905 221125_WJC_METTL3_EV_vs_WT_F06.14484.14484.3 0.232 13/56 R.SSSSLLASPGHISVK.E "sp|A0FGR8|ESYT2_HUMAN,tr|A0A499FIX8|A0A499FIX8_HUMAN,tr|H7BXI1|H7BXI1_HUMAN,tr|A0A087WXU3|A0A087WXU3_HUMAN" 4 1468.7886 1.41 83606 14484 3 1468.789995 490.6035 Extended synaptotagmin-2 OS=Homo sapiens OX=9606 GN=ESYT2 PE=1 SV=1 8.49 2514.3 - 1.76E+06 - - - 0.9784 - 1.995 0.139 - 221.8 1 2 0 0.0014 15 0 0 0 1.79E+07 1.27E+07 - - - 1.8915 0.9999 221125_WJC_METTL3_EV_vs_WT_F06.14485.14485.3 3.28E-05 16/56 R.SSSSLLASPGHISVK[136.11].E "sp|A0FGR8|ESYT2_HUMAN,tr|A0A499FIX8|A0A499FIX8_HUMAN,tr|H7BXI1|H7BXI1_HUMAN,tr|A0A087WXU3|A0A087WXU3_HUMAN" 4 1476.8028 1.47 83607 14485 3 1476.80725 493.2749 Extended synaptotagmin-2 OS=Homo sapiens OX=9606 GN=ESYT2 PE=1 SV=1 8.49 2514.3 - 1.17E+06 - - - 3.0417 - 2.749 0.467 - 242.8 1 2 0 0.0045 15 0 0 0 1.86E+07 1.27E+07 - - - 6.384 1 221125_WJC_METTL3_EV_vs_WT_F06.14488.14488.2 3.80E-06 20/24 K.SVEEGK[136.11]IDGIIDK[136.11].T sp|Q96A49|SYAP1_HUMAN 1 1417.7635 1.22 83610 14488 2 1417.765416 709.889 Synapse-associated protein 1 OS=Homo sapiens OX=9606 GN=SYAP1 PE=1 SV=1 4.32 2514.7 - 985808 - - - 1.3338 - 3.353 0.547 - 1178.4 1 2 1 0.0019 13 0 0 0 1.51E+08 1.24E+08 - - - 6.1857 1 221125_WJC_METTL3_EV_vs_WT_F06.14490.14490.2 2.01E-11 17/34 M.AYEPQGGSGYDYSYAGGR[166.11].G "sp|P61978|HNRPK_HUMAN,tr|S4R359|S4R359_HUMAN,tr|Q5T6W2|Q5T6W2_HUMAN" 3 1906.7997 1.28 83612 14490 2 1906.798519 954.4071 Heterogeneous nuclear ribonucleoprotein K OS=Homo sapiens OX=9606 GN=HNRNPK PE=1 SV=1 4.37 2515 - 886284 - - - -0.6409 - 3.133 0.775 - 948.5 1 1 0 -0.0012 18 0 0 0 8.14E+06 6.37E+06 - - - 7.5724 0.9936 221125_WJC_METTL3_EV_vs_WT_F06.14492.14492.4 0.00736 Dec-78 K.NQDHYAVLGLGHVR[166.11].Y "sp|Q99543|DNJC2_HUMAN,tr|F2Z3H0|F2Z3H0_HUMAN,tr|C9IZ83|C9IZ83_HUMAN,tr|H7C3L7|H7C3L7_HUMAN,tr|F2Z3N9|F2Z3N9_HUMAN" 5 1587.8145 0.46 83614 14492 4 1587.816107 397.9609 DnaJ homolog subfamily C member 2 OS=Homo sapiens OX=9606 GN=DNAJC2 PE=1 SV=4 6.92 2515.3 - 779445 - - - 0.985 - 2.188 0.209 - 129.2 1 2 0 0.0016 14 0 0 0 1.40E+06 3.02E+06 - - - 1.3297 0.9986 221125_WJC_METTL3_EV_vs_WT_F06.14493.14493.3 2.73E-06 Nov-68 M.AYEPQGGSGYDYSYAGGR.G "sp|P61978|HNRPK_HUMAN,tr|S4R359|S4R359_HUMAN,tr|Q5T6W2|Q5T6W2_HUMAN" 3 1896.7915 1.67 83615 14493 3 1896.790987 633.2711 Heterogeneous nuclear ribonucleoprotein K OS=Homo sapiens OX=9606 GN=HNRNPK PE=1 SV=1 4.37 2515.4 - 773776 - - - -0.2552 - 1.889 0.683 - 86.9 1 1 0 -0.0005 18 0 0 0 4.32E+06 2.59E+06 - - - 7.7385 0.9997 221125_WJC_METTL3_EV_vs_WT_F06.14497.14497.3 9.42E-05 Dec-48 K.SVEEGKIDGIIDK.T sp|Q96A49|SYAP1_HUMAN 1 1401.7351 0.97 83618 14497 3 1401.735929 468.2523 Synapse-associated protein 1 OS=Homo sapiens OX=9606 GN=SYAP1 PE=1 SV=1 4.32 2515.8 - 2.00E+07 - - - 0.5736 - 2.055 0.465 - 107.7 1 2 1 0.0008 13 0 0 0 6.52E+08 6.74E+08 - - - 5.6769 1 221125_WJC_METTL3_EV_vs_WT_F06.14498.14498.3 5.56E-05 14/52 R.NALQQENHIIDGVK[136.11].V "sp|Q9GZT3|SLIRP_HUMAN,tr|H0YJW7|H0YJW7_HUMAN,tr|A0A087WUN7|A0A087WUN7_HUMAN,tr|G3V2S9|G3V2S9_HUMAN,tr|H0YJ40|H0YJ40_HUMAN,tr|G3V4X6|G3V4X6_HUMAN" 6 1585.8304 1.23 83619 14498 3 1585.831041 529.6174 "SRA stem-loop-interacting RNA-binding protein, mitochondrial OS=Homo sapiens OX=9606 GN=SLIRP PE=1 SV=1" 5.32 2515.8 - 1.59E+07 - - - 0.4238 - 2.799 0.516 - 291.5 1 2 0 0.0007 14 0 0 0 1.09E+08 8.90E+07 - - - 7.028 1 221125_WJC_METTL3_EV_vs_WT_F06.14499.14499.2 0.000445 15/18 R.KDAEAWFNEK.S "sp|P13645|K1C10_HUMAN,sp|Q7Z3Y7|K1C28_HUMAN,tr|A0A1B0GVI3|A0A1B0GVI3_HUMAN" 3 1236.5775 6.01 83620 14499 2 1236.577756 619.296 "Keratin, type I cytoskeletal 10 OS=Homo sapiens OX=9606 GN=KRT10 PE=1 SV=6" 4.68 2515.8 - 7.38E+06 - - - 0.2054 - 3.074 0.509 - 850.7 1 2 0 0.0003 10 0 0 0 2.08E+08 3.46E+07 - - - 5.935 1 221125_WJC_METTL3_EV_vs_WT_F06.14500.14500.3 2.57E-07 18/40 R.LVNHFVEEFK[136.11]R[166.11].K "sp|P0DMV8|HS71A_HUMAN,sp|P0DMV9|HS71B_HUMAN,tr|V9GZ37|V9GZ37_HUMAN,tr|A0A0G2JIW1|A0A0G2JIW1_HUMAN" 4 1434.7739 0.22 83621 14500 3 1434.774541 479.2652 Heat shock 70 kDa protein 1A OS=Homo sapiens OX=9606 GN=HSPA1A PE=1 SV=1 6.76 2515.9 - 5.95E+06 - - - 0.4788 - 3.241 0.565 - 734.1 1 2 0 0.0007 11 0 0 0 4.74E+08 2.13E+09 - - - 8.1795 0.9982 221125_WJC_METTL3_EV_vs_WT_F06.14501.14501.4 0.011 Nov-84 R.AELR[166.11]DDPIISTHLAK[136.11].L sp|O00231|PSD11_HUMAN 1 1695.9275 0.63 83622 14501 4 1695.927941 424.9891 26S proteasome non-ATPase regulatory subunit 11 OS=Homo sapiens OX=9606 GN=PSMD11 PE=1 SV=3 5.38 2515.9 - 4.14E+06 - - - 0.2872 - 1.72 0.343 - 70.1 1 2 1 0.0005 15 0 0 0 4.45E+07 7.11E+07 - - - 2.4054 1 221125_WJC_METTL3_EV_vs_WT_F06.14502.14502.3 1.26E-09 20/56 M.PGHLQEGFGC[160.03]VVTNR.F sp|Q8NC51|PAIRB_HUMAN 1 1669.7995 0.65 83623 14502 3 1669.801187 557.6071 Plasminogen activator inhibitor 1 RNA-binding protein OS=Homo sapiens OX=9606 GN=SERBP1 PE=1 SV=2 7.13 2516 - 4.08E+06 - - - 1.0259 - 3.363 0.625 - 639.9 1 2 0 0.0017 15 0 0 0 1.14E+08 1.74E+08 - - - 8.6724 1 221125_WJC_METTL3_EV_vs_WT_F06.14506.14506.3 9.32E-05 Nov-56 K.KAEAGAGSATEFQFR.G "sp|Q9NQ39|RS10L_HUMAN,sp|P46783|RS10_HUMAN" 2 1568.7583 16.51 83627 14506 3 1568.760511 523.9267 Putative 40S ribosomal protein S10-like OS=Homo sapiens OX=9606 GN=RPS10P5 PE=5 SV=1 6.14 2516.3 - 1.92E+06 - - - 1.3966 - 2.413 0.514 - 163 1 2 0 0.0022 15 0 0 0 1.74E+07 1.05E+06 - - - 6.5685 0.9063 221125_WJC_METTL3_EV_vs_WT_F06.14507.14507.2 0.0149 17/20 V.EEGKIDGIIDK.T sp|Q96A49|SYAP1_HUMAN 1 1215.6347 1.16 83628 14507 2 1215.635112 608.8246 Synapse-associated protein 1 OS=Homo sapiens OX=9606 GN=SYAP1 PE=1 SV=1 4.32 2516.4 - 1.12E+06 - - - 0.3529 - 2.566 0.399 - 931.7 1 1 1 0.0004 11 0 0 0 3.36E+07 2.91E+07 - - - 4.5372 0.9997 221125_WJC_METTL3_EV_vs_WT_F06.14509.14509.2 4.34E-05 20-Aug K.IWHHTFYNELR.V "sp|Q6S8J3|POTEE_HUMAN,sp|P63261|ACTG_HUMAN,sp|P68133|ACTS_HUMAN,sp|Q9BYX7|ACTBM_HUMAN,sp|P68032|ACTC_HUMAN,sp|P60709|ACTB_HUMAN,sp|A5A3E0|POTEF_HUMAN,sp|P0CG38|POTEI_HUMAN,sp|P0CG39|POTEJ_HUMAN,tr|A0A804GS07|A0A804GS07_HUMAN,tr|I3L3I0|I3L3I0_HUMAN,tr|G5E9R0|G5E9R0_HUMAN,tr|E7EVS6|E7EVS6_HUMAN,tr|A0A6Q8PFE4|A0A6Q8PFE4_HUMAN,tr|J3KT65|J3KT65_HUMAN,tr|I3L3R2|I3L3R2_HUMAN,tr|K7EM38|K7EM38_HUMAN,tr|A0A6Q8PH58|A0A6Q8PH58_HUMAN,tr|I3L1U9|I3L1U9_HUMAN,tr|A0A804HKV3|A0A804HKV3_HUMAN,tr|A0A2R8Y793|A0A2R8Y793_HUMAN,tr|I3L4N8|I3L4N8_HUMAN,tr|C9JUM1|C9JUM1_HUMAN,tr|C9JZR7|C9JZR7_HUMAN,tr|A0A2R8YGF8|A0A2R8YGF8_HUMAN,tr|A6NL76|A6NL76_HUMAN" 26 1514.7419 0.54 83630 14509 2 1514.740953 758.3782 POTE ankyrin domain family member E OS=Homo sapiens OX=9606 GN=POTEE PE=2 SV=3 6.92 2516.6 - 899121 - - - -0.6133 - 1.827 0.404 - 164.2 1 2 0 -0.0009 11 0 0 0 2.67E+06 4.91E+06 - - - 3.655 1 221125_WJC_METTL3_EV_vs_WT_F06.14510.14510.3 2.30E-09 16/68 R.WLHSMTDDPPTTKPLTAR.K sp|Q9UI09|NDUAC_HUMAN 1 2066.0255 1.17 83631 14510 3 2066.025231 689.6824 NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 12 OS=Homo sapiens OX=9606 GN=NDUFA12 PE=1 SV=1 6.75 2516.7 - 893420 - - - -0.135 - 2.608 0.579 - 163.4 1 2 0 -0.0003 18 0 0 0 3.36E+06 2.87E+06 - - - 7.3822 1 221125_WJC_METTL3_EV_vs_WT_F06.14512.14512.2 2.39E-12 17/36 R.GVFAGTNTGPNNSNTTFQK[136.11].R "sp|Q9NYF8|BCLF1_HUMAN,tr|H0YF14|H0YF14_HUMAN" 2 1961.9323 6.04 83633 14512 2 1961.929494 981.9734 Bcl-2-associated transcription factor 1 OS=Homo sapiens OX=9606 GN=BCLAF1 PE=1 SV=2 8.75 2517 - 741030 - - - -1.4139 - 3.699 0.679 - 780 1 2 0 -0.0028 19 0 0 0 2.07E+07 3.43E+06 - - - 7.2712 0.9982 221125_WJC_METTL3_EV_vs_WT_F06.14513.14513.3 4.45E-06 Dec-68 M.AYEPQGGSGYDYSYAGGR[166.11].G "sp|P61978|HNRPK_HUMAN,tr|S4R359|S4R359_HUMAN,tr|Q5T6W2|Q5T6W2_HUMAN" 3 1906.7997 1.67 83634 14513 3 1906.801549 636.6072 Heterogeneous nuclear ribonucleoprotein K OS=Homo sapiens OX=9606 GN=HNRNPK PE=1 SV=1 4.37 2517.1 - 547846 - - - 0.9482 - 2.081 0.63 - 117.6 1 1 0 0.0018 18 0 0 0 4.32E+06 2.59E+06 - - - 7.3882 0.9998 221125_WJC_METTL3_EV_vs_WT_F06.14516.14516.3 0.00154 Dec-52 R.TYSLGSALRPSTSR.S "sp|P08670|VIME_HUMAN,tr|B0YJC4|B0YJC4_HUMAN,tr|A0A1B0GVG8|A0A1B0GVG8_HUMAN,tr|A0A1B0GTT5|A0A1B0GTT5_HUMAN" 4 1494.7791 2.47 83636 14516 3 1494.779901 499.267 Vimentin OS=Homo sapiens OX=9606 GN=VIM PE=1 SV=4 10.83 2517.5 - 6.04E+06 - - - 0.5653 - 1.626 0.42 - 152 1 2 0 0.0008 14 0 0 0 4.00E+07 1.62E+07 - - - 4.5142 0.9999 221125_WJC_METTL3_EV_vs_WT_F06.14517.14517.3 0.000336 15/56 R.FLSNGHVTIPGQQDK[136.11].D sp|P35579|MYH9_HUMAN 1 1647.846 1.02 83637 14517 3 1647.847262 550.2893 Myosin-9 OS=Homo sapiens OX=9606 GN=MYH9 PE=1 SV=4 6.74 2517.5 - 3.12E+06 - - - 0.7543 - 2.158 0.443 - 145.7 1 2 0 0.0012 15 0 0 0 2.22E+07 2.17E+07 - - - 5.4857 1 221125_WJC_METTL3_EV_vs_WT_F06.14518.14518.2 4.34E-08 18/24 K.SVEEGKIDGIIDK.T sp|Q96A49|SYAP1_HUMAN 1 1401.7351 1.22 83638 14518 2 1401.734946 701.8748 Synapse-associated protein 1 OS=Homo sapiens OX=9606 GN=SYAP1 PE=1 SV=1 4.32 2517.6 - 8.91E+06 - - - -0.1277 - 3.092 0.547 - 926.4 1 2 1 -0.0002 13 0 0 0 1.44E+08 1.19E+08 - - - 5.9782 1 221125_WJC_METTL3_EV_vs_WT_F06.14523.14523.2 5.49E-06 14/20 R.LVNHFVEEFK[136.11]R[166.11].K "sp|P0DMV8|HS71A_HUMAN,sp|P0DMV9|HS71B_HUMAN,tr|V9GZ37|V9GZ37_HUMAN,tr|A0A0G2JIW1|A0A0G2JIW1_HUMAN" 4 1434.7739 0.54 83643 14523 2 1434.774537 718.3942 Heat shock 70 kDa protein 1A OS=Homo sapiens OX=9606 GN=HSPA1A PE=1 SV=1 6.76 2517.8 - 2.06E+06 - - - 0.476 - 2.774 0.608 - 966.5 1 2 0 0.0007 11 0 0 0 8.62E+07 1.60E+08 - - - 6.2916 1 221125_WJC_METTL3_EV_vs_WT_F06.14524.14524.3 5.08E-11 18/60 R.LAQMISDHNDADFEEK.V "sp|Q14157|UBP2L_HUMAN,tr|Q5VU78|Q5VU78_HUMAN,tr|F8W726|F8W726_HUMAN,tr|Q5VU81|Q5VU81_HUMAN,tr|Q5VU79|Q5VU79_HUMAN,tr|Q5VU80|Q5VU80_HUMAN,tr|Q5VU77|Q5VU77_HUMAN" 7 1861.8152 2.45 83644 14524 3 1861.817351 621.6124 Ubiquitin-associated protein 2-like OS=Homo sapiens OX=9606 GN=UBAP2L PE=1 SV=2 4.1 2517.9 - 1.89E+06 - - - 1.1322 - 3.606 0.548 - 469.8 1 2 0 0.0021 16 0 0 0 5.51E+08 2.25E+08 - - - 7.9401 1 221125_WJC_METTL3_EV_vs_WT_F06.14527.14527.3 3.58E-09 20/68 K.VAHGALSDGAIDAVETQK.D sp|O60318|GANP_HUMAN 1 1780.8955 1.46 83647 14527 3 1780.895525 594.6391 Germinal-center associated nuclear protein OS=Homo sapiens OX=9606 GN=MCM3AP PE=1 SV=2 4.54 2518.2 - 1.23E+06 - - - -0.0095 - 3.591 0.549 - 571.8 1 2 0 0 18 0 0 0 9.13E+06 6.27E+06 - - - 7.8442 0.9879 221125_WJC_METTL3_EV_vs_WT_F06.14529.14529.3 0.0419 Oct-48 K.SVEEGKIDGIIDK[136.11].T sp|Q96A49|SYAP1_HUMAN 1 1409.7493 - 83649 14529 3 1409.750871 470.9237 Synapse-associated protein 1 OS=Homo sapiens OX=9606 GN=SYAP1 PE=1 SV=1 4.32 2518.3 - 1.07E+06 - - - 1.0966 - 1.814 0.232 - 59.3 1 2 1 0.0015 13 0 0 0 - - - - - 2.7408 0.9904 221125_WJC_METTL3_EV_vs_WT_F06.14530.14530.3 0.000167 Dec-68 G.LLQDDAHPTLVTYADHSK[136.11].L "sp|Q86U44|MTA70_HUMAN,tr|F5H6D8|F5H6D8_HUMAN,tr|H0YFV6|H0YFV6_HUMAN,tr|B4DTN4|B4DTN4_HUMAN" 4 2031.0153 0.001 83650 14530 3 2031.015621 678.0124 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 5.13 2518.5 - 983001 - - - 0.1728 - 1.958 0.454 - 101.6 1 1 0 0.0004 18 0 0 0 0.00E+00 1.42E+07 - - - 5.2747 1 221125_WJC_METTL3_EV_vs_WT_F06.14538.14538.3 3.63E-10 20/56 M.PGHLQEGFGC[160.03]VVTNR[166.11].F sp|Q8NC51|PAIRB_HUMAN 1 1679.8077 0.65 83656 14538 3 1679.807931 560.9432 Plasminogen activator inhibitor 1 RNA-binding protein OS=Homo sapiens OX=9606 GN=SERBP1 PE=1 SV=2 7.13 2519.5 - 2.06E+07 - - - 0.1113 - 3.572 0.565 - 643.9 1 2 0 0.0002 15 0 0 0 1.15E+08 1.78E+08 - - - 8.1612 1 221125_WJC_METTL3_EV_vs_WT_F06.14539.14539.3 7.69E-10 15/52 K.DHASIQMNVAEVDK[136.11].V "sp|P63220|RS21_HUMAN,tr|Q9BYK1|Q9BYK1_HUMAN,tr|Q8WVC2|Q8WVC2_HUMAN" 3 1563.7443 0.24 83657 14539 3 1563.738963 522.2554 40S ribosomal protein S21 OS=Homo sapiens OX=9606 GN=RPS21 PE=1 SV=1 4.54 2519.6 - 4.05E+06 - - - -3.3848 - 3.19 0.658 - 495.8 1 2 0 -0.0053 14 0 0 0 7.01E+06 2.88E+07 - - - 8.9574 0.9989 221125_WJC_METTL3_EV_vs_WT_F06.14541.14541.3 2.60E-08 15/32 V.NHFVEEFK[136.11]R[166.11].K "sp|P0DMV8|HS71A_HUMAN,sp|P0DMV9|HS71B_HUMAN,tr|V9GZ37|V9GZ37_HUMAN,tr|A0A0G2JIW1|A0A0G2JIW1_HUMAN" 4 1222.6214 0.22 83659 14541 3 1222.621699 408.5477 Heat shock 70 kDa protein 1A OS=Homo sapiens OX=9606 GN=HSPA1A PE=1 SV=1 6.76 2519.7 - 3.01E+06 - - - 0.2642 - 3.003 0.574 - 388.3 1 1 0 0.0003 9 0 0 0 7.34E+06 3.29E+07 - - - 8.2534 0.9998 221125_WJC_METTL3_EV_vs_WT_F06.14542.14542.3 0.000325 Nov-48 K.HIMIDLGTGNNNK.L "sp|P83876|TXN4A_HUMAN,tr|K7ESL1|K7ESL1_HUMAN" 2 1425.7034 16.47 83660 14542 3 1425.703147 476.2418 Thioredoxin-like protein 4A OS=Homo sapiens OX=9606 GN=TXNL4A PE=1 SV=1 6.74 2519.7 - 2.69E+06 - - - -0.2111 - 1.943 0.367 - 120.2 1 2 0 -0.0003 13 0 0 0 1.88E+07 1.14E+06 - - - 4.4325 0.9559 221125_WJC_METTL3_EV_vs_WT_F06.14544.14544.3 1.07 Aug-52 R.TYSLGSALR[166.11]PSTSR[166.11].S "sp|P08670|VIME_HUMAN,tr|B0YJC4|B0YJC4_HUMAN,tr|A0A1B0GVG8|A0A1B0GVG8_HUMAN,tr|A0A1B0GTT5|A0A1B0GTT5_HUMAN" 4 1514.7956 2.55 83662 14544 3 1514.795984 505.9391 Vimentin OS=Homo sapiens OX=9606 GN=VIM PE=1 SV=4 10.83 2519.9 - 2.31E+06 - - - 0.2561 - 1.235 0.164 - 64.7 1 2 0 0.0004 14 0 0 0 4.97E+07 1.95E+07 - - - 0.9293 1 221125_WJC_METTL3_EV_vs_WT_F06.14545.14545.3 0.00529 15/44 R.VC[160.03]EEIAIIPSKK.L "sp|P08708|RS17_HUMAN,tr|H0YN73|H0YN73_HUMAN,tr|H3BNC9|H3BNC9_HUMAN,tr|H0YN88|H0YN88_HUMAN,tr|A0A075B716|A0A075B716_HUMAN" 5 1385.7588 1.83 83663 14545 3 1385.760373 462.9269 40S ribosomal protein S17 OS=Homo sapiens OX=9606 GN=RPS17 PE=1 SV=2 6.11 2520 - 2.18E+06 - - - 1.1077 - 3.183 0.504 - 321.5 1 2 0 0.0015 12 0 0 0 1.26E+08 6.89E+07 - - - 7.368 0.9997 221125_WJC_METTL3_EV_vs_WT_F06.14546.14546.3 5.95E-06 Nov-56 K.EFYGENIK[136.11]ESPDYER[166.11].L "sp|P51648|AL3A2_HUMAN,tr|I3L1M4|I3L1M4_HUMAN,tr|A0A5F9ZHI5|A0A5F9ZHI5_HUMAN,tr|A0A5F9ZI12|A0A5F9ZI12_HUMAN,tr|J3QS00|J3QS00_HUMAN,tr|A0A5F9ZHN9|A0A5F9ZHN9_HUMAN,tr|A0A5K1VW72|A0A5K1VW72_HUMAN,tr|A0A5F9ZGX4|A0A5F9ZGX4_HUMAN,tr|J3QRD1|J3QRD1_HUMAN" 9 1892.8547 2.96 83664 14546 3 1892.853957 631.9589 Aldehyde dehydrogenase family 3 member A2 OS=Homo sapiens OX=9606 GN=ALDH3A2 PE=1 SV=1 4.25 2520.1 - 514237 - - - -0.4152 - 2.354 0.434 - 86.7 1 2 1 -0.0008 15 0 0 0 8.37E+06 2.82E+06 - - - 5.6124 1 221125_WJC_METTL3_EV_vs_WT_F06.14549.14549.3 2.88E-08 16/60 R.LAQMISDHNDADFEEK[136.11].V "sp|Q14157|UBP2L_HUMAN,tr|Q5VU78|Q5VU78_HUMAN,tr|F8W726|F8W726_HUMAN,tr|Q5VU81|Q5VU81_HUMAN,tr|Q5VU79|Q5VU79_HUMAN,tr|Q5VU80|Q5VU80_HUMAN,tr|Q5VU77|Q5VU77_HUMAN" 7 1869.8294 2.44 83665 14549 3 1869.826126 624.2838 Ubiquitin-associated protein 2-like OS=Homo sapiens OX=9606 GN=UBAP2L PE=1 SV=2 4.1 2520.5 - 9.10E+06 - - - -1.774 - 3.297 0.645 - 392.4 1 2 0 -0.0033 16 0 0 0 5.35E+08 2.19E+08 - - - 8.7913 0.9997 221125_WJC_METTL3_EV_vs_WT_F06.14551.14551.3 7.54E-05 Dec-44 R.QSVEADINGLRR.V "sp|P13645|K1C10_HUMAN,sp|Q7Z3Y8|K1C27_HUMAN,sp|P13646|K1C13_HUMAN,tr|A0A1B0GVI3|A0A1B0GVI3_HUMAN,tr|K7EMD9|K7EMD9_HUMAN,tr|K7ERE3|K7ERE3_HUMAN" 6 1356.711 999 83667 14551 3 1356.707758 453.2443 "Keratin, type I cytoskeletal 10 OS=Homo sapiens OX=9606 GN=KRT10 PE=1 SV=6" 6.07 2520.6 - 2.77E+06 - - - -2.3719 - 2.112 0.401 - 251.9 1 2 0 -0.0032 12 0 0 0 2.46E+07 0.00E+00 - - - 5.0822 0.9989 221125_WJC_METTL3_EV_vs_WT_F06.14554.14554.3 0.0231 16/56 K.QLQEELAEHQVPVEK.L "sp|Q9UPN3|MACF1_HUMAN,tr|H3BQK9|H3BQK9_HUMAN,tr|A0A7P0MQR8|A0A7P0MQR8_HUMAN,tr|H0Y390|H0Y390_HUMAN,tr|H3BPE1|H3BPE1_HUMAN,tr|A0A590UJG2|A0A590UJG2_HUMAN" 6 1775.9054 2.56 83670 14554 3 1775.907651 592.9757 "Microtubule-actin cross-linking factor 1, isoforms 1\2\3\5 OS=Homo sapiens OX=9606 GN=MACF1 PE=1 SV=4" 4.48 2521 - 1.61E+06 - - - 1.2799 - 2.123 0.26 - 255.5 1 2 0 0.0023 15 0 0 0 8.36E+06 3.27E+06 - - - 3.4025 0.9998 221125_WJC_METTL3_EV_vs_WT_F06.14555.14555.4 0.000789 Dec-78 R.INSYGYGDHYIHIK.L sp|Q96EY1|DNJA3_HUMAN 1 1678.8104 1.26 83671 14555 4 1678.807931 420.7099 "DnaJ homolog subfamily A member 3, mitochondrial OS=Homo sapiens OX=9606 GN=DNAJA3 PE=1 SV=2" 6.92 2521.1 - 1.48E+06 - - - -1.4445 - 2.267 0.382 - 79.5 1 2 0 -0.0024 14 0 0 0 3.63E+07 2.88E+07 - - - 2.8481 0.9992 221125_WJC_METTL3_EV_vs_WT_F06.14556.14556.3 4.00E-05 15/72 R.VTVGDAATTAAASSSSVTR[166.11].D sp|Q9ULJ3|ZBT21_HUMAN 1 1760.878 0.39 83672 14556 3 1760.86923 587.9666 Zinc finger and BTB domain-containing protein 21 OS=Homo sapiens OX=9606 GN=ZBTB21 PE=1 SV=2 5.81 2521.2 - 1.36E+06 - - - -4.9754 - 2.863 0.429 - 253.1 1 2 0 -0.0088 19 0 0 0 3.20E+06 8.14E+06 - - - 5.9047 1 221125_WJC_METTL3_EV_vs_WT_F06.14557.14557.4 1.70E-06 17/78 R.INSYGYGDHYIHIK[136.11].L sp|Q96EY1|DNJA3_HUMAN 1 1686.8246 1.21 83673 14557 4 1686.82425 422.7134 "DnaJ homolog subfamily A member 3, mitochondrial OS=Homo sapiens OX=9606 GN=DNAJA3 PE=1 SV=2" 6.92 2521.3 - 1.20E+06 - - - -0.1814 - 2.871 0.56 - 145.6 1 2 0 -0.0003 14 0 0 0 3.45E+07 2.86E+07 - - - 4.484 1 221125_WJC_METTL3_EV_vs_WT_F06.14558.14558.2 7.56E-13 21/30 R.LAQMISDHNDADFEEK.V "sp|Q14157|UBP2L_HUMAN,tr|Q5VU78|Q5VU78_HUMAN,tr|F8W726|F8W726_HUMAN,tr|Q5VU81|Q5VU81_HUMAN,tr|Q5VU79|Q5VU79_HUMAN,tr|Q5VU80|Q5VU80_HUMAN,tr|Q5VU77|Q5VU77_HUMAN" 7 1861.8152 2.89 83674 14558 2 1861.821775 931.9149 Ubiquitin-associated protein 2-like OS=Homo sapiens OX=9606 GN=UBAP2L PE=1 SV=2 4.1 2521.4 - 878688 - - - 3.5084 - 4.031 0.726 - 1249.5 1 2 0 0.0065 16 0 0 0 3.06E+07 1.06E+07 - - - 7.8284 0.9999 221125_WJC_METTL3_EV_vs_WT_F06.14559.14559.2 1.14E-09 16/28 M.PGHLQEGFGC[160.03]VVTNR.F sp|Q8NC51|PAIRB_HUMAN 1 1669.7995 0.68 83675 14559 2 1669.799979 835.907 Plasminogen activator inhibitor 1 RNA-binding protein OS=Homo sapiens OX=9606 GN=SERBP1 PE=1 SV=2 7.13 2521.6 - 754374 - - - 0.3024 - 3.18 0.471 - 855.4 1 2 0 0.0005 15 0 0 0 6.50E+06 9.55E+06 - - - 5.3639 1 221125_WJC_METTL3_EV_vs_WT_F06.14563.14563.2 5.76E-11 19/30 R.LAQMISDHNDADFEEK[136.11].V "sp|Q14157|UBP2L_HUMAN,tr|Q5VU78|Q5VU78_HUMAN,tr|F8W726|F8W726_HUMAN,tr|Q5VU81|Q5VU81_HUMAN,tr|Q5VU79|Q5VU79_HUMAN,tr|Q5VU80|Q5VU80_HUMAN,tr|Q5VU77|Q5VU77_HUMAN" 7 1869.8294 2.87 83679 14563 2 1869.824063 935.922 Ubiquitin-associated protein 2-like OS=Homo sapiens OX=9606 GN=UBAP2L PE=1 SV=2 4.1 2522.1 - 460790 - - - -2.8773 - 3.691 0.717 - 977.1 1 2 0 -0.0054 16 0 0 0 3.04E+07 1.06E+07 - - - 7.5457 0.9983 221125_WJC_METTL3_EV_vs_WT_F06.14564.14564.3 0.439 Dec-68 R.K[136.11]LEC[160.03]LPPEPSPDDPESVK[136.11].L sp|Q96CS3|FAF2_HUMAN 1 2052.0056 1.58 83680 14564 3 2052.000163 685.0092 FAS-associated factor 2 OS=Homo sapiens OX=9606 GN=FAF2 PE=1 SV=2 4.18 2522.2 - 427498 - - - -2.6608 - 2.205 0.286 - 91.2 1 2 0 -0.0055 18 0 0 0 2.64E+06 1.67E+06 - - - 3.6961 0.9999 221125_WJC_METTL3_EV_vs_WT_F06.14567.14567.3 5.47E-05 15/44 R.QIEIQFAQGDR[166.11]K[136.11].T "sp|O75494|SRS10_HUMAN,sp|Q8WXF0|SRS12_HUMAN,tr|Q5JRI1|Q5JRI1_HUMAN" 3 1449.7695 1.28 83681 14567 3 1449.767378 484.2638 Serine\arginine-rich splicing factor 10 OS=Homo sapiens OX=9606 GN=SRSF10 PE=1 SV=1 6.07 2522.6 - 3.97E+06 - - - -1.4616 - 2.383 0.405 - 293.7 1 2 0 -0.0021 12 0 0 0 6.88E+07 5.40E+07 - - - 5.4617 0.9998 221125_WJC_METTL3_EV_vs_WT_F06.14568.14568.4 1.06E-06 14/96 K.LAASIAPEIYGHEDVK[136.11]K[136.11].A sp|P33993|MCM7_HUMAN 1 1856.0015 1.04 83682 14568 4 1856.001305 465.0076 DNA replication licensing factor MCM7 OS=Homo sapiens OX=9606 GN=MCM7 PE=1 SV=4 5.45 2522.7 - 3.52E+06 - - - -0.0857 - 2.928 0.364 - 145.8 1 2 0 -0.0002 17 0 0 0 4.34E+07 4.18E+07 - - - 2.7672 0.9858 221125_WJC_METTL3_EV_vs_WT_F06.14569.14569.2 5.15E-06 16-Oct V.NHFVEEFK[136.11]R[166.11].K "sp|P0DMV8|HS71A_HUMAN,sp|P0DMV9|HS71B_HUMAN,tr|V9GZ37|V9GZ37_HUMAN,tr|A0A0G2JIW1|A0A0G2JIW1_HUMAN" 4 1222.6214 0.6 83683 14569 2 1222.620682 612.318 Heat shock 70 kDa protein 1A OS=Homo sapiens OX=9606 GN=HSPA1A PE=1 SV=1 6.76 2522.7 - 4.15E+06 - - - -0.5676 - 1.894 0.408 - 513.4 1 1 0 -0.0007 9 0 0 0 1.74E+07 2.91E+07 - - - 3.902 0.9929 221125_WJC_METTL3_EV_vs_WT_F06.14571.14571.3 0.00148 18/36 L.VNHFVEEFKR.K "sp|P0DMV8|HS71A_HUMAN,sp|P0DMV9|HS71B_HUMAN,tr|V9GZ37|V9GZ37_HUMAN,tr|A0A0G2JIW1|A0A0G2JIW1_HUMAN" 4 1303.6673 0.15 83685 14571 3 1303.666805 435.563 Heat shock 70 kDa protein 1A OS=Homo sapiens OX=9606 GN=HSPA1A PE=1 SV=1 6.73 2522.9 - 2.24E+06 - - - -0.395 - 2.936 0.349 - 661.5 1 1 0 -0.0005 10 0 0 0 1.55E+07 1.05E+08 - - - 5.5763 1 221125_WJC_METTL3_EV_vs_WT_F06.14576.14576.3 6.94E-07 16/64 K.LAASIAPEIYGHEDVKK.A sp|P33993|MCM7_HUMAN 1 1839.9731 1.15 83690 14576 3 1839.974225 614.3316 DNA replication licensing factor MCM7 OS=Homo sapiens OX=9606 GN=MCM7 PE=1 SV=4 5.45 2523.5 - 1.26E+06 - - - 0.631 - 2.947 0.485 - 260.4 1 2 0 0.0012 17 0 0 0 1.97E+07 1.72E+07 - - - 6.6773 1 221125_WJC_METTL3_EV_vs_WT_F06.14577.14577.2 1.53E-09 19/38 R.LLEGEDAHLSSQQASGQSYS.S sp|P08779|K1C16_HUMAN 1 2105.9502 - 83691 14577 2 2105.947823 1053.9824 "Keratin, type I cytoskeletal 16 OS=Homo sapiens OX=9606 GN=KRT16 PE=1 SV=4" 4.13 2523.7 - 1.19E+06 - - - -1.1078 - 3.832 0.663 - 781.5 1 1 0 -0.0023 20 0 0 0 - - - - - 7.24 1 221125_WJC_METTL3_EV_vs_WT_F06.14583.14583.4 2.84E-10 21/114 K.R[166.11]GLLQDDAHPTLVTYADHSK[136.11].L "sp|Q86U44|MTA70_HUMAN,tr|F5H6D8|F5H6D8_HUMAN,tr|H0YFV6|H0YFV6_HUMAN,tr|B4DTN4|B4DTN4_HUMAN" 4 2254.1461 0.001 83695 14583 4 2254.14402 564.5438 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 5.99 2524.5 - 4.42E+06 - - - -0.9294 - 3.54 0.559 - 457 1 2 0 -0.0021 20 0 0 0 0.00E+00 3.93E+07 - - - 4.5136 0.9438 221125_WJC_METTL3_EV_vs_WT_F06.14584.14584.3 0.00908 Nov-76 R.LLEGEDAHLSSQQASGQSYS.S sp|P08779|K1C16_HUMAN 1 2105.9502 - 83696 14584 3 2105.948999 702.9907 "Keratin, type I cytoskeletal 16 OS=Homo sapiens OX=9606 GN=KRT16 PE=1 SV=4" 4.13 2524.5 - 4.34E+06 - - - -0.5494 - 1.88 0.328 - 67.4 1 1 0 -0.0012 20 0 0 0 - - - - - 3.728 1 221125_WJC_METTL3_EV_vs_WT_F06.14586.14586.3 2.31E-08 15/56 R.QIMEEC[160.03]ENLKLEC[160.03]SK.L "sp|Q15643|TRIPB_HUMAN,tr|H0YJ97|H0YJ97_HUMAN" 2 1909.8584 1.1 83698 14586 3 1909.857696 637.6267 Thyroid receptor-interacting protein 11 OS=Homo sapiens OX=9606 GN=TRIP11 PE=1 SV=3 4.49 2524.6 - 4.20E+06 - - - -0.3529 - 3.32 0.617 - 365.1 1 2 1 -0.0007 15 0 0 0 3.96E+07 3.59E+07 - - - 8.5499 0.9999 221125_WJC_METTL3_EV_vs_WT_F06.14587.14587.3 7.27E-08 16/56 R.QIMEEC[160.03]ENLK[136.11]LEC[160.03]SK[136.11].L "sp|Q15643|TRIPB_HUMAN,tr|H0YJ97|H0YJ97_HUMAN" 2 1925.8868 1.1 83699 14587 3 1925.885568 642.9695 Thyroid receptor-interacting protein 11 OS=Homo sapiens OX=9606 GN=TRIP11 PE=1 SV=3 4.49 2524.6 - 3.94E+06 - - - -0.6241 - 2.893 0.561 - 446.2 1 2 1 -0.0012 15 0 0 0 3.90E+07 3.54E+07 - - - 7.5662 1 221125_WJC_METTL3_EV_vs_WT_F06.14588.14588.3 6.85E-06 16/64 K.MAPVPLDDSNRPASLTK.D "sp|Q9NYF8|BCLF1_HUMAN,tr|E9PKI6|E9PKI6_HUMAN,tr|A0A1W2PQ43|A0A1W2PQ43_HUMAN,tr|E9PK91|E9PK91_HUMAN,tr|E9PJA7|E9PJA7_HUMAN,tr|E9PK09|E9PK09_HUMAN,tr|E9PQN2|E9PQN2_HUMAN" 7 1810.9247 2.45 83700 14588 3 1810.926262 604.6489 Bcl-2-associated transcription factor 1 OS=Homo sapiens OX=9606 GN=BCLAF1 PE=1 SV=2 5.71 2524.7 - 2.41E+06 - - - 0.8438 - 2.484 0.462 - 224.8 1 2 0 0.0015 17 0 0 0 1.10E+09 4.47E+08 - - - 5.989 0.9993 221125_WJC_METTL3_EV_vs_WT_F06.14589.14589.3 0.00197 Nov-40 R.EK[136.11]QPPIDNIIR[166.11].A "sp|P52292|IMA1_HUMAN,tr|J3QLL0|J3QLL0_HUMAN,tr|J3KS65|J3KS65_HUMAN,tr|A0A7I2V3Z3|A0A7I2V3Z3_HUMAN,tr|A0A7I2YQE1|A0A7I2YQE1_HUMAN,tr|A0A7I2V487|A0A7I2V487_HUMAN,tr|A0A7I2V351|A0A7I2V351_HUMAN" 7 1339.7579 1.27 83701 14589 3 1339.756707 447.5932 Importin subunit alpha-1 OS=Homo sapiens OX=9606 GN=KPNA2 PE=1 SV=1 6.17 2524.7 - 2.36E+06 - - - -0.8681 - 2.374 0.342 - 257.6 1 2 1 -0.0012 11 0 0 0 6.66E+07 5.26E+07 - - - 4.8088 0.992 221125_WJC_METTL3_EV_vs_WT_F06.14592.14592.3 0.0156 Dec-56 R.ASTLLRDEELEEIKK.E "sp|Q99653|CHP1_HUMAN,tr|H0YLX1|H0YLX1_HUMAN,tr|F5GX29|F5GX29_HUMAN,tr|H0YKE7|H0YKE7_HUMAN,tr|H0YNG9|H0YNG9_HUMAN" 5 1772.952 1.74 83704 14592 3 1772.954916 591.9913 Calcineurin B homologous protein 1 OS=Homo sapiens OX=9606 GN=CHP1 PE=1 SV=3 4.59 2525.1 - 841698 - - - 1.6481 - 2.091 0.248 - 154.8 1 2 1 0.0029 15 0 0 0 1.04E+07 6.01E+06 - - - 3.2289 0.9997 221125_WJC_METTL3_EV_vs_WT_F06.14594.14594.3 8.36E-07 13/56 R.ASTLLR[166.11]DEELEEIK[136.11]K[136.11].E "sp|Q99653|CHP1_HUMAN,tr|H0YLX1|H0YLX1_HUMAN,tr|F5GX29|F5GX29_HUMAN,tr|H0YKE7|H0YKE7_HUMAN,tr|H0YNG9|H0YNG9_HUMAN" 5 1798.9887 1.74 83706 14594 3 1798.984903 600.6702 Calcineurin B homologous protein 1 OS=Homo sapiens OX=9606 GN=CHP1 PE=1 SV=3 4.59 2525.4 - 716278 - - - -2.0906 - 2.841 0.449 - 162.3 1 2 1 -0.0038 15 0 0 0 1.04E+07 6.01E+06 - - - 6.2695 0.8825 221125_WJC_METTL3_EV_vs_WT_F06.14598.14598.3 0.000337 Nov-36 L.VNHFVEEFK[136.11]R[166.11].K "sp|P0DMV8|HS71A_HUMAN,sp|P0DMV9|HS71B_HUMAN,tr|V9GZ37|V9GZ37_HUMAN,tr|A0A0G2JIW1|A0A0G2JIW1_HUMAN" 4 1321.6898 0.15 83709 14598 3 1321.689003 441.5705 Heat shock 70 kDa protein 1A OS=Homo sapiens OX=9606 GN=HSPA1A PE=1 SV=1 6.73 2525.9 - 4.02E+06 - - - -0.5954 - 2.23 0.203 - 251.6 1 1 0 -0.0008 10 0 0 0 1.59E+07 1.06E+08 - - - 3.1452 1 221125_WJC_METTL3_EV_vs_WT_F06.14599.14599.3 5.54E-06 18/48 R.HTPELPLAPRPLK.E "sp|Q9Y618|NCOR2_HUMAN,tr|C9J7T7|C9J7T7_HUMAN,tr|C9JE98|C9JE98_HUMAN,tr|C9J0Q5|C9J0Q5_HUMAN,tr|A0A384DVL6|A0A384DVL6_HUMAN" 5 1467.8562 2.8 83710 14599 3 1467.855336 490.2927 Nuclear receptor corepressor 2 OS=Homo sapiens OX=9606 GN=NCOR2 PE=1 SV=3 8.75 2526 - 1.18E+06 - - - -0.5777 - 3.296 0.45 - 436.5 1 2 0 -0.0008 13 0 0 0 2.51E+07 8.94E+06 - - - 6.7906 0.995 221125_WJC_METTL3_EV_vs_WT_F06.14602.14602.3 3.02 17/48 K.LK[136.11]DVLLQVDDER[166.11]R[166.11].N sp|P35579|MYH9_HUMAN 1 1625.9095 0.87 83713 14602 3 1625.908267 542.9771 Myosin-9 OS=Homo sapiens OX=9606 GN=MYH9 PE=1 SV=4 4.68 2526.2 - 2.84E+06 - - - -0.7645 - 2.398 0.21 - 274.1 1 2 1 -0.0012 13 0 0 0 1.21E+08 1.39E+08 - - - 3.2523 0.9758 221125_WJC_METTL3_EV_vs_WT_F06.14604.14604.3 0.00877 Oct-52 N.RTTPSYVAFTDTER[166.11].L "sp|P48741|HSP77_HUMAN,sp|P54652|HSP72_HUMAN,sp|P0DMV8|HS71A_HUMAN,sp|P34931|HS71L_HUMAN,sp|P11142|HSP7C_HUMAN,sp|P0DMV9|HS71B_HUMAN,sp|P17066|HSP76_HUMAN,tr|E9PQQ4|E9PQQ4_HUMAN,tr|E9PNE6|E9PNE6_HUMAN,tr|E9PKE3|E9PKE3_HUMAN,tr|E9PLF4|E9PLF4_HUMAN,tr|Q53FA3|Q53FA3_HUMAN,tr|E9PI65|E9PI65_HUMAN,tr|E9PK54|E9PK54_HUMAN,tr|E9PN25|E9PN25_HUMAN,tr|E9PPY6|E9PPY6_HUMAN,tr|E9PQK7|E9PQK7_HUMAN,tr|A0A0G2JIW1|A0A0G2JIW1_HUMAN" 18 1652.8034 - 83715 14604 3 1652.806627 551.9417 Putative heat shock 70 kDa protein 7 OS=Homo sapiens OX=9606 GN=HSPA7 PE=5 SV=2 6.07 2526.4 - 1.75E+06 - - - 1.9706 - 2.153 0.396 - 115.5 1 1 0 0.0033 14 0 0 0 - - - - - 4.9921 0.9998 221125_WJC_METTL3_EV_vs_WT_F06.14606.14606.4 0.00153 19/84 K.SLGTRPPHVFAIADK.A "sp|Q9UM54|MYO6_HUMAN,tr|A0A590UK86|A0A590UK86_HUMAN,tr|A0A590UK71|A0A590UK71_HUMAN,tr|A0A0D9SGC1|A0A0D9SGC1_HUMAN,tr|A0A0A0MRM8|A0A0A0MRM8_HUMAN,tr|A0A5F9ZI03|A0A5F9ZI03_HUMAN,tr|A0A590UK22|A0A590UK22_HUMAN,tr|A0A590UJY4|A0A590UJY4_HUMAN,tr|A0A590UJ40|A0A590UJ40_HUMAN,tr|A0A590UJ75|A0A590UJ75_HUMAN,tr|E7EW20|E7EW20_HUMAN,tr|A0A590UKB0|A0A590UKB0_HUMAN,tr|A0A1Y0BRN3|A0A1Y0BRN3_HUMAN,tr|A0A590UJW9|A0A590UJW9_HUMAN" 14 1607.8784 0.08 83717 14606 4 1607.878139 402.9769 Unconventional myosin-VI OS=Homo sapiens OX=9606 GN=MYO6 PE=1 SV=4 8.49 2526.6 - 717659 - - - -0.1474 - 3.108 0.359 - 199.4 1 2 0 -0.0002 15 0 0 0 9.22E+06 1.22E+08 - - - 2.7564 1 221125_WJC_METTL3_EV_vs_WT_F06.14612.14612.3 8.33E-06 16/64 K.MAPVPLDDSNR[166.11]PASLTK[136.11].D "sp|Q9NYF8|BCLF1_HUMAN,tr|E9PKI6|E9PKI6_HUMAN,tr|A0A1W2PQ43|A0A1W2PQ43_HUMAN,tr|E9PK91|E9PK91_HUMAN,tr|E9PJA7|E9PJA7_HUMAN,tr|E9PK09|E9PK09_HUMAN,tr|E9PQN2|E9PQN2_HUMAN" 7 1828.9472 2.45 83721 14612 3 1828.94729 610.6563 Bcl-2-associated transcription factor 1 OS=Homo sapiens OX=9606 GN=BCLAF1 PE=1 SV=2 5.71 2527.2 - 6.96E+06 - - - 0.047 - 3.024 0.5 - 234.3 1 2 0 0.0001 17 0 0 0 1.09E+09 4.47E+08 - - - 6.91 0.9997 221125_WJC_METTL3_EV_vs_WT_F06.14613.14613.3 0.00637 14/40 R.EKQPPIDNIIR.A "sp|P52292|IMA1_HUMAN,tr|J3QLL0|J3QLL0_HUMAN,tr|J3KS65|J3KS65_HUMAN,tr|A0A7I2V3Z3|A0A7I2V3Z3_HUMAN,tr|A0A7I2YQE1|A0A7I2YQE1_HUMAN,tr|A0A7I2V487|A0A7I2V487_HUMAN,tr|A0A7I2V351|A0A7I2V351_HUMAN" 7 1321.7354 1.26 83722 14613 3 1321.734924 441.5857 Importin subunit alpha-1 OS=Homo sapiens OX=9606 GN=KPNA2 PE=1 SV=1 6.17 2527.3 - 4.90E+06 - - - -0.3601 - 2.521 0.403 - 363.7 1 2 1 -0.0005 11 0 0 0 7.16E+07 5.67E+07 - - - 5.6597 0.9995 221125_WJC_METTL3_EV_vs_WT_F06.14614.14614.4 6.32E-05 15/72 K.LK[136.11]DVLLQVDDER[166.11]R[166.11].N sp|P35579|MYH9_HUMAN 1 1625.9095 0.91 83723 14614 4 1625.906165 407.4847 Myosin-9 OS=Homo sapiens OX=9606 GN=MYH9 PE=1 SV=4 4.68 2527.3 - 4.56E+06 - - - -2.0573 - 2.803 0.43 - 341 1 2 1 -0.0033 13 0 0 0 1.18E+08 1.31E+08 - - - 3.3499 0.9879 221125_WJC_METTL3_EV_vs_WT_F06.14618.14618.3 0.000516 15/64 R.QLNPESIRPGGPGGLSR.S "sp|Q7L2E3|DHX30_HUMAN,tr|H7BXY3|H7BXY3_HUMAN" 2 1733.9173 7.68 83727 14618 3 1733.923155 578.9797 ATP-dependent RNA helicase DHX30 OS=Homo sapiens OX=9606 GN=DHX30 PE=1 SV=1 9.6 2527.7 - 758626 - - - 3.3883 - 2.491 0.167 - 277.2 1 2 0 0.0059 17 0 0 0 7.93E+07 1.03E+07 - - - 2.706 0.9986 221125_WJC_METTL3_EV_vs_WT_F06.14626.14626.3 1.74E-07 16/56 R.EHQLASASELPLGSR.P "sp|O60232|ZNRD2_HUMAN,tr|H0YEB6|H0YEB6_HUMAN,tr|G3V1B8|G3V1B8_HUMAN" 3 1593.8111 1.2 83733 14626 3 1593.81162 532.2776 Protein ZNRD2 OS=Homo sapiens OX=9606 GN=ZNRD2 PE=1 SV=1 5.4 2528.7 - 4.98E+06 - - - 0.3363 - 3.124 0.559 - 305 1 1 0 0.0005 15 0 0 0 6.30E+07 5.26E+07 - - - 7.7445 0.9999 221125_WJC_METTL3_EV_vs_WT_F06.14628.14628.4 4.52E-07 16/72 K.LKDVLLQVDDERR.N sp|P35579|MYH9_HUMAN 1 1597.8788 0.92 83735 14628 4 1597.877898 400.477 Myosin-9 OS=Homo sapiens OX=9606 GN=MYH9 PE=1 SV=4 4.68 2528.8 - 5.00E+06 - - - -0.5457 - 2.855 0.492 - 400 1 2 1 -0.0009 13 0 0 0 1.18E+08 1.28E+08 - - - 3.8971 0.9997 221125_WJC_METTL3_EV_vs_WT_F06.14629.14629.3 0.000193 15/48 K.LKDVLLQVDDERR.N sp|P35579|MYH9_HUMAN 1 1597.8788 0.87 83736 14629 3 1597.878173 533.6335 Myosin-9 OS=Homo sapiens OX=9606 GN=MYH9 PE=1 SV=4 4.68 2528.8 - 4.31E+06 - - - -0.3736 - 2.413 0.426 - 283.8 1 2 1 -0.0006 13 0 0 0 1.20E+08 1.38E+08 - - - 5.6776 1 221125_WJC_METTL3_EV_vs_WT_F06.14631.14631.3 3.64E-05 22/64 L.LC[160.03]GEEQGSDAALHFNPR.L sp|P47929|LEG7_HUMAN 1 1899.8534 0.53 83738 14631 3 1899.857117 634.2917 Galectin-7 OS=Homo sapiens OX=9606 GN=LGALS7 PE=1 SV=2 4.65 2529 - 1.20E+06 - - - 1.9775 - 4.04 0.582 - 830.9 1 1 0 0.0038 17 0 0 0 1.66E+07 3.13E+07 - - - 8.555 0.9999 221125_WJC_METTL3_EV_vs_WT_F06.14632.14632.3 0.000413 Dec-32 K.ELWDQFHK[136.11]R[166.11].G sp|O15119|TBX3_HUMAN 1 1275.6479 1.13 83739 14632 3 1275.647701 426.2233 T-box transcription factor TBX3 OS=Homo sapiens OX=9606 GN=TBX3 PE=1 SV=4 6.85 2529.1 - 916370 - - - -0.1756 - 2.147 0.447 - 256.7 1 2 0 -0.0002 9 0 0 0 2.17E+07 1.91E+07 - - - 5.8263 1 221125_WJC_METTL3_EV_vs_WT_F06.14635.14635.2 3.71E-09 13/32 K.MAPVPLDDSNR[166.11]PASLTK[136.11].D "sp|Q9NYF8|BCLF1_HUMAN,tr|E9PKI6|E9PKI6_HUMAN,tr|A0A1W2PQ43|A0A1W2PQ43_HUMAN,tr|E9PK91|E9PK91_HUMAN,tr|E9PJA7|E9PJA7_HUMAN,tr|E9PK09|E9PK09_HUMAN,tr|E9PQN2|E9PQN2_HUMAN" 7 1828.9472 2.58 83742 14635 2 1828.948107 915.4809 Bcl-2-associated transcription factor 1 OS=Homo sapiens OX=9606 GN=BCLAF1 PE=1 SV=2 5.71 2529.5 - 423762 - - - 0.4937 - 2.682 0.628 - 286.4 1 2 0 0.0009 17 0 0 0 3.82E+07 1.48E+07 - - - 6.1046 0.9997 221125_WJC_METTL3_EV_vs_WT_F06.14639.14639.3 2.22E-05 15/52 R.LK[136.11]GSGNLEAIHIIK[136.11].K "sp|P78371|TCPB_HUMAN,tr|F8VQ14|F8VQ14_HUMAN,tr|F5GWF6|F5GWF6_HUMAN" 3 1507.9057 0.48 83744 14639 3 1507.904596 503.6425 T-complex protein 1 subunit beta OS=Homo sapiens OX=9606 GN=CCT2 PE=1 SV=4 8.6 2529.9 - 4.82E+06 - - - -0.7408 - 2.428 0.415 - 138.5 1 2 1 -0.0011 14 0 0 0 2.68E+08 5.55E+08 - - - 5.5239 1 221125_WJC_METTL3_EV_vs_WT_F06.14641.14641.3 2.15E-09 20/60 R.AC[160.03]GVSRPVIAC[160.03]SVTIK.E "sp|P55769|NH2L1_HUMAN,tr|B1AHD1|B1AHD1_HUMAN,tr|A0A3B3IUA2|A0A3B3IUA2_HUMAN,tr|A0A3B3IRU2|A0A3B3IRU2_HUMAN" 4 1716.9015 0.62 83746 14641 3 1716.899396 573.3078 NHP2-like protein 1 OS=Homo sapiens OX=9606 GN=SNU13 PE=1 SV=3 8.96 2530 - 2.19E+06 - - - -1.2231 - 3.638 0.514 - 476.3 1 2 0 -0.0021 16 0 0 0 3.95E+07 6.32E+07 - - - 7.5837 1 221125_WJC_METTL3_EV_vs_WT_F06.14643.14643.2 4.44E-09 17/32 K.MAPVPLDDSNRPASLTK.D "sp|Q9NYF8|BCLF1_HUMAN,tr|E9PKI6|E9PKI6_HUMAN,tr|A0A1W2PQ43|A0A1W2PQ43_HUMAN,tr|E9PK91|E9PK91_HUMAN,tr|E9PJA7|E9PJA7_HUMAN,tr|E9PK09|E9PK09_HUMAN,tr|E9PQN2|E9PQN2_HUMAN" 7 1810.9247 2.58 83748 14643 2 1810.925459 906.4696 Bcl-2-associated transcription factor 1 OS=Homo sapiens OX=9606 GN=BCLAF1 PE=1 SV=2 5.71 2530.3 - 1.55E+06 - - - 0.4003 - 2.917 0.675 - 518.6 1 2 0 0.0007 17 0 0 0 3.82E+07 1.48E+07 - - - 6.6583 1 221125_WJC_METTL3_EV_vs_WT_F06.14645.14645.3 4.94E-07 13/64 K.FATDGEGYKPC[160.03]DPQVIR.D "sp|Q01082|SPTB2_HUMAN,tr|A0A087WUZ3|A0A087WUZ3_HUMAN,tr|F8W6C1|F8W6C1_HUMAN" 3 1951.9098 1.61 83750 14645 3 1951.913545 651.6439 "Spectrin beta chain, non-erythrocytic 1 OS=Homo sapiens OX=9606 GN=SPTBN1 PE=1 SV=2" 4.56 2530.5 - 584018 - - - 1.9125 - 2.605 0.521 - 138.7 1 2 0 0.0037 17 0 0 0 5.85E+06 3.63E+06 - - - 6.7664 0.9999 221125_WJC_METTL3_EV_vs_WT_F06.14650.14650.3 0.00111 15/60 K.SLGNILQAKPTSSPAK.G "sp|Q13428|TCOF_HUMAN,tr|E7ETY2|E7ETY2_HUMAN,tr|H0Y8Y7|H0Y8Y7_HUMAN,tr|A0A3B3IS06|A0A3B3IS06_HUMAN,tr|A0A6I8PRA0|A0A6I8PRA0_HUMAN" 5 1610.8992 0.38 83753 14650 3 1610.899656 537.9737 Treacle protein OS=Homo sapiens OX=9606 GN=TCOF1 PE=1 SV=3 10 2531.1 - 3.19E+06 - - - 0.3011 - 2.239 0.417 - 129.5 1 2 0 0.0005 16 0 0 0 3.80E+07 1.01E+08 - - - 5.2572 0.9989 221125_WJC_METTL3_EV_vs_WT_F06.14651.14651.3 0.0032 Sep-44 R.QRGDQLVPFSTK.S "sp|Q9BTV4|TMM43_HUMAN,tr|V9GY05|V9GY05_HUMAN" 2 1374.7256 0.65 83754 14651 3 1374.724698 459.2491 Transmembrane protein 43 OS=Homo sapiens OX=9606 GN=TMEM43 PE=1 SV=1 8.75 2531.1 - 2.62E+06 - - - -0.6292 - 2.2 0.333 - 151.1 1 2 1 -0.0009 12 0 0 0 4.45E+07 6.85E+07 - - - 4.4379 1 221125_WJC_METTL3_EV_vs_WT_F06.14661.14661.3 2.05E-08 18/76 R.ILHVNGFNGEGGEEDPQAAR.S "sp|P63092|GNAS2_HUMAN,sp|Q5JWF2|GNAS1_HUMAN,tr|A0A590UJ22|A0A590UJ22_HUMAN,tr|A0A590UJQ2|A0A590UJQ2_HUMAN,tr|A0A590UJR6|A0A590UJR6_HUMAN,tr|A0A590UJS2|A0A590UJS2_HUMAN,tr|A0A0A0MR13|A0A0A0MR13_HUMAN,tr|B0AZR9|B0AZR9_HUMAN,tr|A0A590UJI6|A0A590UJI6_HUMAN,tr|A0A590UJQ9|A0A590UJQ9_HUMAN,tr|S4R3E3|S4R3E3_HUMAN,tr|A0A590UJ58|A0A590UJ58_HUMAN,tr|Q5JWD1|Q5JWD1_HUMAN,tr|A0A590UJB7|A0A590UJB7_HUMAN,tr|A0A590UJX3|A0A590UJX3_HUMAN,tr|A0A7I2V5R6|A0A7I2V5R6_HUMAN,tr|H0Y7E8|H0Y7E8_HUMAN,tr|A0A590UJY8|A0A590UJY8_HUMAN,tr|S4R3V9|S4R3V9_HUMAN" 19 2108.9875 0.76 83762 14661 3 2108.982277 704.0031 Guanine nucleotide-binding protein G(s) subunit alpha isoforms short OS=Homo sapiens OX=9606 GN=GNAS PE=1 SV=1 4.4 2532.4 - 1.07E+06 - - - -2.4979 - 3.555 0.61 - 250 1 2 0 -0.0053 20 0 0 0 8.46E+06 1.11E+07 - - - 8.4165 1 221125_WJC_METTL3_EV_vs_WT_F06.14663.14663.3 1.50E-05 19/48 R.R[166.11]LESIATTLVSHK[136.11].A sp|Q9P2R3|ANFY1_HUMAN 1 1471.8477 1.35 83764 14663 3 1471.846686 491.6232 Rabankyrin-5 OS=Homo sapiens OX=9606 GN=ANKFY1 PE=1 SV=2 8.75 2532.6 - 845963 - - - -0.7209 - 3.142 0.45 - 504.2 1 2 0 -0.0011 13 0 0 0 2.01E+07 1.49E+07 - - - 6.6608 0.9976 221125_WJC_METTL3_EV_vs_WT_F06.14666.14666.2 0.00464 14/26 R.LK[136.11]GSGNLEAIHIIK[136.11].K "sp|P78371|TCPB_HUMAN,tr|F8VQ14|F8VQ14_HUMAN,tr|F5GWF6|F5GWF6_HUMAN" 3 1507.9057 0.42 83767 14666 2 1507.90785 754.9601 T-complex protein 1 subunit beta OS=Homo sapiens OX=9606 GN=CCT2 PE=1 SV=4 8.6 2533 - 646343 - - - 1.4172 - 2.623 0.441 - 327.1 1 2 1 0.0021 14 0 0 0 8.70E+06 2.06E+07 - - - 4.7175 0.9995 221125_WJC_METTL3_EV_vs_WT_F06.14670.14670.3 0.0838 Dec-52 R.LKGSGNLEAIHIIK.K "sp|P78371|TCPB_HUMAN,tr|F8VQ14|F8VQ14_HUMAN,tr|F5GWF6|F5GWF6_HUMAN" 3 1491.8773 0.48 83770 14670 3 1491.877905 498.2997 T-complex protein 1 subunit beta OS=Homo sapiens OX=9606 GN=CCT2 PE=1 SV=4 8.6 2533.4 - 1.42E+07 - - - 0.3968 - 2.37 0.378 - 108.3 1 2 1 0.0006 14 0 0 0 2.68E+08 5.55E+08 - - - 5.0473 0.9997 221125_WJC_METTL3_EV_vs_WT_F06.14672.14672.3 0.000934 19/48 R.LREQLQLLEEQHR.A "sp|Q15149|PLEC_HUMAN,tr|H0YDN1|H0YDN1_HUMAN" 2 1690.9115 1.39 83772 14672 3 1690.913528 564.6444 Plectin OS=Homo sapiens OX=9606 GN=PLEC PE=1 SV=3 5.5 2533.5 - 1.95E+06 - - - 1.2189 - 3.338 0.36 - 668.9 1 2 1 0.0021 13 0 0 0 2.86E+07 2.05E+07 - - - 5.8212 0.9996 221125_WJC_METTL3_EV_vs_WT_F06.14673.14673.4 2.57E-05 17/72 R.LREQLQLLEEQHR.A "sp|Q15149|PLEC_HUMAN,tr|H0YDN1|H0YDN1_HUMAN" 2 1690.9115 1.1 83773 14673 4 1690.913733 423.7351 Plectin OS=Homo sapiens OX=9606 GN=PLEC PE=1 SV=3 5.5 2533.6 - 797915 - - - 1.3401 - 3.168 0.41 - 379 1 2 1 0.0023 13 0 0 0 1.29E+07 1.18E+07 - - - 3.2215 0.9993 221125_WJC_METTL3_EV_vs_WT_F06.14682.14682.4 0.00016 14/72 R.LR[166.11]EQLQLLEEQHR[166.11].A "sp|Q15149|PLEC_HUMAN,tr|H0YDN1|H0YDN1_HUMAN" 2 1710.928 1.09 83780 14682 4 1710.923648 428.7393 Plectin OS=Homo sapiens OX=9606 GN=PLEC PE=1 SV=3 5.5 2534.5 - 1.32E+06 - - - -2.5477 - 2.344 0.43 - 263.7 1 2 1 -0.0044 13 0 0 0 1.29E+07 1.19E+07 - - - 3.2834 1 221125_WJC_METTL3_EV_vs_WT_F06.14683.14683.3 1.89E-09 24/72 R.LLEAQAC[160.03]TGGIIHPTTGQK.L sp|P15924|DESP_HUMAN 1 1994.0255 2.1 83781 14683 3 1994.025891 665.6824 Desmoplakin OS=Homo sapiens OX=9606 GN=DSP PE=1 SV=3 6.74 2534.6 - 1.26E+06 - - - 0.1906 - 4.259 0.631 - 554.5 1 2 0 0.0004 19 0 0 0 6.27E+07 2.99E+07 - - - 9.1349 1 221125_WJC_METTL3_EV_vs_WT_F06.14684.14684.2 2.88E-09 15/26 R.ETQTEC[160.03]EWTVDTSK.L sp|P15924|DESP_HUMAN 1 1712.7199 9.97 83782 14684 2 1712.724051 857.3672 Desmoplakin OS=Homo sapiens OX=9606 GN=DSP PE=1 SV=3 4 2534.8 - 1.06E+06 - - - 2.3968 - 3.019 0.699 - 1053 1 2 0 0.0041 14 0 0 0 4.78E+07 4.79E+06 - - - 6.9753 1 221125_WJC_METTL3_EV_vs_WT_F06.14685.14685.3 9.33E-07 15/60 R.QLQEERPELSESELTR.L "sp|P17480|UBF1_HUMAN,tr|E9PKP7|E9PKP7_HUMAN,tr|E9PLT2|E9PLT2_HUMAN" 3 1942.9596 1.48 83783 14685 3 1942.961839 648.6605 Nucleolar transcription factor 1 OS=Homo sapiens OX=9606 GN=UBTF PE=1 SV=1 4.33 2534.9 - 953441 - - - 1.1529 - 3.049 0.534 - 339.9 1 2 0 0.0022 16 0 0 0 8.33E+07 5.62E+07 - - - 7.3534 1 221125_WJC_METTL3_EV_vs_WT_F06.14691.14691.3 7.51E-09 19/60 R.QLQEER[166.11]PELSESELTR[166.11].L "sp|P17480|UBF1_HUMAN,tr|E9PKP7|E9PKP7_HUMAN,tr|E9PLT2|E9PLT2_HUMAN" 3 1962.9761 1.48 83787 14691 3 1962.977114 655.3327 Nucleolar transcription factor 1 OS=Homo sapiens OX=9606 GN=UBTF PE=1 SV=1 4.33 2535.7 - 1.64E+06 - - - 0.4967 - 2.995 0.58 - 554.5 1 2 0 0.001 16 0 0 0 8.33E+07 5.62E+07 - - - 7.8208 0.997 221125_WJC_METTL3_EV_vs_WT_F06.14693.14693.3 0.00616 13/48 R.RLESIATTLVSHK.A sp|Q9P2R3|ANFY1_HUMAN 1 1453.8253 1.32 83789 14693 3 1453.826754 485.6157 Rabankyrin-5 OS=Homo sapiens OX=9606 GN=ANKFY1 PE=1 SV=2 8.75 2535.8 - 1.56E+06 - - - 1.0159 - 2.301 0.165 - 296.2 1 2 0 0.0015 13 0 0 0 2.01E+07 1.52E+07 - - - 2.6386 1 221125_WJC_METTL3_EV_vs_WT_F06.14695.14695.2 1.14E-06 17/26 R.LKGSGNLEAIHIIK.K "sp|P78371|TCPB_HUMAN,tr|F8VQ14|F8VQ14_HUMAN,tr|F5GWF6|F5GWF6_HUMAN" 3 1491.8773 0.42 83791 14695 2 1491.875315 746.9459 T-complex protein 1 subunit beta OS=Homo sapiens OX=9606 GN=CCT2 PE=1 SV=4 8.6 2536 - 791360 - - - -1.3393 - 3.011 0.583 - 520.4 1 2 1 -0.002 14 0 0 0 8.70E+06 2.06E+07 - - - 6.1125 0.9981 221125_WJC_METTL3_EV_vs_WT_F06.14696.14696.3 0.00933 Sep-36 K.LKEENFFGPK.E sp|Q9NZI8|IF2B1_HUMAN 1 1207.6237 1.66 83792 14696 3 1207.624094 403.5485 Insulin-like growth factor 2 mRNA-binding protein 1 OS=Homo sapiens OX=9606 GN=IGF2BP1 PE=1 SV=2 6.14 2536.2 - 477466 - - - 0.3064 - 1.503 0.381 - 88 1 2 1 0.0004 10 0 0 0 8.25E+06 4.98E+06 - - - 3.9776 1 221125_WJC_METTL3_EV_vs_WT_F06.14701.14701.2 4.22E-07 15/24 R.IEDVTPIPSDSTR.R "sp|P62263|RS14_HUMAN,tr|A0A2R8Y811|A0A2R8Y811_HUMAN" 2 1428.7096 1.54 83795 14701 2 1428.710527 715.3621 40S ribosomal protein S14 OS=Homo sapiens OX=9606 GN=RPS14 PE=1 SV=3 4.03 2536.8 - 1.20E+06 - - - 0.6215 - 2.888 0.559 - 767.6 1 2 0 0.0009 13 0 0 0 1.01E+08 6.58E+07 - - - 5.8915 1 221125_WJC_METTL3_EV_vs_WT_F06.14702.14702.2 2.10E-08 15/32 F.ASSLVSGLNSSASEPAK[136.11].E "sp|Q86U44|MTA70_HUMAN,tr|F5H6D8|F5H6D8_HUMAN,tr|H0YFV6|H0YFV6_HUMAN,tr|B4DTN4|B4DTN4_HUMAN" 4 1611.8195 0.03 83796 14702 2 1611.819745 806.917 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 6.05 2537 - 1.02E+06 - - - 0.1334 - 2.708 0.606 - 629.5 1 1 0 0.0002 17 0 0 0 3.89E+07 1.44E+09 - - - 5.9661 0.9988 221125_WJC_METTL3_EV_vs_WT_F06.14703.14703.2 1.50E-05 13/24 R.IEDVTPIPSDSTR[166.11].R "sp|P62263|RS14_HUMAN,tr|A0A2R8Y811|A0A2R8Y811_HUMAN" 2 1438.7179 1.54 83797 14703 2 1438.723948 720.3662 40S ribosomal protein S14 OS=Homo sapiens OX=9606 GN=RPS14 PE=1 SV=3 4.03 2537.1 - 875092 - - - 4.1975 - 2.724 0.473 - 552 1 2 0 0.006 13 0 0 0 1.01E+08 6.58E+07 - - - 5.1046 0.9998 221125_WJC_METTL3_EV_vs_WT_F06.14704.14704.4 0.000599 17/78 K.VFIQHITLSDEER[166.11]K[136.11].L "sp|Q14527|HLTF_HUMAN,tr|H7C5K0|H7C5K0_HUMAN,tr|A0A0C4DGA6|A0A0C4DGA6_HUMAN" 3 1731.9275 1.17 83798 14704 4 1731.928115 433.9891 Helicase-like transcription factor OS=Homo sapiens OX=9606 GN=HLTF PE=1 SV=2 5.44 2537.2 - 584538 - - - 0.3817 - 2.724 0.367 - 159.6 1 2 0 0.0007 14 0 0 0 5.02E+07 4.30E+07 - - - 2.7849 0.9995 221125_WJC_METTL3_EV_vs_WT_F06.14711.14711.4 0.00124 Nov-78 K.VFIQHITLSDEERK.L "sp|Q14527|HLTF_HUMAN,tr|H7C5K0|H7C5K0_HUMAN,tr|A0A0C4DGA6|A0A0C4DGA6_HUMAN" 3 1713.905 1.17 83803 14711 4 1713.906826 429.4835 Helicase-like transcription factor OS=Homo sapiens OX=9606 GN=HLTF PE=1 SV=2 5.44 2538 - 1.28E+06 - - - 1.0747 - 1.964 0.329 - 63.2 1 2 0 0.0018 14 0 0 0 5.02E+07 4.30E+07 - - - 2.3348 1 221125_WJC_METTL3_EV_vs_WT_F06.14713.14713.3 4.71E-09 18/72 R.LLEAQAC[160.03]TGGIIHPTTGQK[136.11].L sp|P15924|DESP_HUMAN 1 2002.0397 2.06 83805 14713 3 2002.040319 668.3538 Desmoplakin OS=Homo sapiens OX=9606 GN=DSP PE=1 SV=3 6.74 2538.2 - 1.05E+06 - - - 0.3037 - 3.753 0.576 - 293.3 1 2 0 0.0006 19 0 0 0 6.25E+07 3.04E+07 - - - 8.2109 0.9901 221125_WJC_METTL3_EV_vs_WT_F06.14722.14722.3 0.000124 Nov-52 K.VFIQHITLSDEERK.L "sp|Q14527|HLTF_HUMAN,tr|H7C5K0|H7C5K0_HUMAN,tr|A0A0C4DGA6|A0A0C4DGA6_HUMAN" 3 1713.905 0.58 83812 14722 3 1713.921286 572.3089 Helicase-like transcription factor OS=Homo sapiens OX=9606 GN=HLTF PE=1 SV=2 5.44 2539.2 - 906161 - - - 9.5116 - 2.322 0.403 - 129.5 1 2 0 0.0163 14 0 0 0 2.08E+07 3.60E+07 - - - 5.2673 1 221125_WJC_METTL3_EV_vs_WT_F06.14725.14725.2 4.41E-07 14/22 R.DADETKEWIEEK.N "sp|Q13813|SPTN1_HUMAN,tr|A0A0D9SF54|A0A0D9SF54_HUMAN,tr|A0A0D9SGF6|A0A0D9SGF6_HUMAN" 3 1491.6729 1.73 83815 14725 2 1491.674264 746.8437 "Spectrin alpha chain, non-erythrocytic 1 OS=Homo sapiens OX=9606 GN=SPTAN1 PE=1 SV=3" 4.08 2539.6 - 499706 - - - 0.9017 - 2.904 0.566 - 501.3 1 2 1 0.0013 12 0 0 0 7.01E+06 4.06E+06 - - - 6.0261 0.8258 221125_WJC_METTL3_EV_vs_WT_F06.14726.14726.4 0.967 Aug-78 R.EVESVDLPHC[160.03]HLIK.G "sp|Q15165|PON2_HUMAN,tr|A0A0J9YXF2|A0A0J9YXF2_HUMAN,tr|A0A0J9YXM1|A0A0J9YXM1_HUMAN,tr|A0A2Q2SAK4|A0A2Q2SAK4_HUMAN,tr|G3XAK4|G3XAK4_HUMAN" 5 1674.8399 0.83 83816 14726 4 1674.838866 419.7173 Serum paraoxonase\arylesterase 2 OS=Homo sapiens OX=9606 GN=PON2 PE=1 SV=4 5.28 2539.7 - 358367 - - - -0.6424 - 1.628 0.117 - 40.2 2 2 0 -0.0011 14 0 0 0 5.84E+06 7.00E+06 - - - 0.192 0.9993 221125_WJC_METTL3_EV_vs_WT_F06.14727.14727.2 2.84E-05 30-Nov K.SQLLAPPPPSAPPGNK[136.11].T "sp|P49750|YLPM1_HUMAN,tr|F8VU51|F8VU51_HUMAN" 2 1577.8657 4.43 83817 14727 2 1577.870213 789.9401 YLP motif-containing protein 1 OS=Homo sapiens OX=9606 GN=YLPM1 PE=1 SV=4 8.47 2539.8 - 355040 - - - 2.8653 - 2.07 0.465 - 360.3 1 2 0 0.0045 16 0 0 0 5.33E+07 1.20E+07 - - - 4.2628 1 221125_WJC_METTL3_EV_vs_WT_F06.14728.14728.2 8.46E-06 13/26 R.ETQTEC[160.03]EWTVDTSK[136.11].L sp|P15924|DESP_HUMAN 1 1720.7341 9.97 83818 14728 2 1720.734307 861.3743 Desmoplakin OS=Homo sapiens OX=9606 GN=DSP PE=1 SV=3 4 2540 - 333158 - - - 0.0936 - 2.912 0.564 - 715.3 1 2 0 0.0002 14 0 0 0 4.78E+07 4.79E+06 - - - 5.8889 0.9988 221125_WJC_METTL3_EV_vs_WT_F06.14729.14729.3 0.00733 Oct-80 K.AEPAAPPAAPSTPAPPPAVPK.E sp|P48634|PRC2A_HUMAN 1 1933.0309 0.47 83819 14729 3 1933.028222 645.3509 Protein PRRC2A OS=Homo sapiens OX=9606 GN=PRRC2A PE=1 SV=3 6.05 2540.1 - 199387 - - - -1.3921 - 1.843 0.299 - 69 1 2 0 -0.0027 21 0 0 0 9.84E+06 2.11E+07 - - - 3.3386 0.9998 221125_WJC_METTL3_EV_vs_WT_F06.14735.14735.3 0.0065 Nov-40 K.MK[136.11]EIAEAYLGK[136.11].T "sp|P11142|HSP7C_HUMAN,tr|E9PQQ4|E9PQQ4_HUMAN,tr|E9PKE3|E9PKE3_HUMAN,tr|E9PN89|E9PN89_HUMAN,tr|E9PLF4|E9PLF4_HUMAN,tr|E9PI65|E9PI65_HUMAN,tr|E9PK54|E9PK54_HUMAN,tr|E9PPY6|E9PPY6_HUMAN,tr|E9PQK7|E9PQK7_HUMAN" 9 1267.6817 0.15 83823 14735 3 1267.683648 423.5678 Heat shock cognate 71 kDa protein OS=Homo sapiens OX=9606 GN=HSPA8 PE=1 SV=1 5.9 2540.7 - 3.94E+06 - - - 1.5288 - 2.524 0.471 - 167.8 1 2 1 0.0019 11 0 0 0 7.71E+06 5.03E+07 - - - 6.4208 0.9999 221125_WJC_METTL3_EV_vs_WT_F06.14737.14737.3 6.66E-06 Dec-36 R.HTHQLYNFLR.F "sp|Q8WV92|MITD1_HUMAN,tr|H7C3Q6|H7C3Q6_HUMAN" 2 1327.6786 0.64 83825 14737 3 1327.680617 443.5668 MIT domain-containing protein 1 OS=Homo sapiens OX=9606 GN=MITD1 PE=1 SV=1 8.76 2540.8 - 1.13E+06 - - - 1.5538 - 2.578 0.414 - 334 1 2 0 0.0021 10 0 0 0 2.00E+07 3.15E+07 - - - 5.9208 0.9855 221125_WJC_METTL3_EV_vs_WT_F06.14739.14739.3 0.0378 Aug-40 K.MKEIAEAYLGK.T "sp|P11142|HSP7C_HUMAN,tr|E9PQQ4|E9PQQ4_HUMAN,tr|E9PKE3|E9PKE3_HUMAN,tr|E9PN89|E9PN89_HUMAN,tr|E9PLF4|E9PLF4_HUMAN,tr|E9PI65|E9PI65_HUMAN,tr|E9PK54|E9PK54_HUMAN,tr|E9PPY6|E9PPY6_HUMAN,tr|E9PQK7|E9PQK7_HUMAN" 9 1251.6533 0.15 83827 14739 3 1251.654694 418.225 Heat shock cognate 71 kDa protein OS=Homo sapiens OX=9606 GN=HSPA8 PE=1 SV=1 5.9 2541.1 - 621197 - - - 1.1057 - 1.725 0.227 - 104.3 1 2 1 0.0014 11 0 0 0 7.37E+06 4.94E+07 - - - 2.6193 0.9602 221125_WJC_METTL3_EV_vs_WT_F06.14741.14741.3 3.41E-05 15/44 G.MK[136.11]AEGFVDALHR[166.11].V "sp|Q96I24|FUBP3_HUMAN,tr|A0A494C1K6|A0A494C1K6_HUMAN" 2 1390.7146 1.03 83829 14741 3 1390.717929 464.5788 Far upstream element-binding protein 3 OS=Homo sapiens OX=9606 GN=FUBP3 PE=1 SV=2 6.51 2541.3 - 513396 - - - 2.3758 - 2.424 0.479 - 219.3 1 1 1 0.0033 12 0 0 0 1.26E+07 1.22E+07 - - - 6.3337 0.999 221125_WJC_METTL3_EV_vs_WT_F06.14743.14743.2 8.13E-06 22-Dec R.DADETK[136.11]EWIEEK[136.11].N "sp|Q13813|SPTN1_HUMAN,tr|A0A0D9SF54|A0A0D9SF54_HUMAN,tr|A0A0D9SGF6|A0A0D9SGF6_HUMAN" 3 1507.7013 1.73 83831 14743 2 1507.701433 754.8579 "Spectrin alpha chain, non-erythrocytic 1 OS=Homo sapiens OX=9606 GN=SPTAN1 PE=1 SV=3" 4.08 2541.6 - 291846 - - - 0.0756 - 2.367 0.561 - 357.4 1 2 1 0.0001 12 0 0 0 7.01E+06 4.06E+06 - - - 5.4516 0.9998 221125_WJC_METTL3_EV_vs_WT_F06.14745.14745.3 0.000472 13/68 R.KLEC[160.03]LPPEPSPDDPESVK.L sp|Q96CS3|FAF2_HUMAN 1 2035.9772 3.15 83833 14745 3 2035.982394 679.6664 FAS-associated factor 2 OS=Homo sapiens OX=9606 GN=FAF2 PE=1 SV=2 4.18 2541.9 - 169754 - - - 2.5398 - 2.181 0.444 - 149.2 1 2 0 0.0052 18 0 0 0 1.22E+07 3.88E+06 - - - 5.4305 1 221125_WJC_METTL3_EV_vs_WT_F06.14748.14748.3 4.81E-09 16/56 R.C[160.03]SDSDGLAPPQHLIR[166.11].V "sp|P04637|P53_HUMAN,tr|E7ESS1|E7ESS1_HUMAN,tr|J3KP33|J3KP33_HUMAN,tr|E9PFT5|E9PFT5_HUMAN,tr|A0A087X1Q1|A0A087X1Q1_HUMAN,tr|A0A0U1RQC9|A0A0U1RQC9_HUMAN,tr|A0A087WT22|A0A087WT22_HUMAN,tr|A0A087WXZ1|A0A087WXZ1_HUMAN,tr|E7EQX7|E7EQX7_HUMAN" 9 1674.8023 1.14 83834 14748 3 1674.803299 559.2747 Cellular tumor antigen p53 OS=Homo sapiens OX=9606 GN=TP53 PE=1 SV=4 5.21 2542.3 - 4.56E+06 - - - 0.5822 - 2.466 0.567 - 359.9 1 2 0 0.001 15 0 0 0 1.51E+08 1.32E+08 - - - 7.2164 1 221125_WJC_METTL3_EV_vs_WT_F06.14749.14749.2 2.42E-07 19/32 R.AIGGGLSSVGGGSSTIK.Y "sp|P48668|K2C6C_HUMAN,sp|P02538|K2C6A_HUMAN" 2 1446.7678 999 83835 14749 2 1446.768277 724.3912 "Keratin, type II cytoskeletal 6C OS=Homo sapiens OX=9606 GN=KRT6C PE=1 SV=3" 8.8 2542.3 - 2.00E+06 - - - 0.3145 - 3.297 0.567 - 1032.7 1 2 0 0.0005 17 0 0 0 3.24E+07 0.00E+00 - - - 6.1618 1 221125_WJC_METTL3_EV_vs_WT_F06.14750.14750.3 2.53E-06 16/52 K.VFIQHITLSDEER[166.11]K[136.11].L "sp|Q14527|HLTF_HUMAN,tr|H7C5K0|H7C5K0_HUMAN,tr|A0A0C4DGA6|A0A0C4DGA6_HUMAN" 3 1731.9275 0.74 83836 14750 3 1731.927568 578.3164 Helicase-like transcription factor OS=Homo sapiens OX=9606 GN=HLTF PE=1 SV=2 5.44 2542.4 - 2.46E+06 - - - 0.0658 - 2.904 0.506 - 285.7 1 2 0 0.0001 14 0 0 0 4.56E+07 6.13E+07 - - - 7.0145 0.9999 221125_WJC_METTL3_EV_vs_WT_F06.14752.14752.3 2.04E-07 14/48 K.HFSTEDGIFQGQR[166.11].H "sp|Q6RFH5|WDR74_HUMAN,tr|E9PS41|E9PS41_HUMAN" 2 1530.7091 1.22 83838 14752 3 1530.712357 511.2436 WD repeat-containing protein 74 OS=Homo sapiens OX=9606 GN=WDR74 PE=1 SV=1 5.32 2542.5 - 1.09E+06 - - - 2.1441 - 2.404 0.514 - 243.6 1 2 0 0.0033 13 0 0 0 2.42E+07 1.98E+07 - - - 6.6478 0.9694 221125_WJC_METTL3_EV_vs_WT_F06.14753.14753.3 0.000192 Nov-44 G.MKAEGFVDALHR.V "sp|Q96I24|FUBP3_HUMAN,tr|A0A494C1K6|A0A494C1K6_HUMAN" 2 1372.6922 1.04 83839 14753 3 1372.69249 458.5713 Far upstream element-binding protein 3 OS=Homo sapiens OX=9606 GN=FUBP3 PE=1 SV=2 6.51 2542.6 - 1.00E+06 - - - 0.244 - 2.086 0.452 - 116.4 1 1 1 0.0003 12 0 0 0 1.26E+07 1.21E+07 - - - 5.6173 0.9997 221125_WJC_METTL3_EV_vs_WT_F06.14754.14754.3 3.04E-05 Dec-60 R.NLGLFQHHDAITGTAK.D sp|Q16706|MA2A1_HUMAN 1 1721.8849 0.74 83840 14754 3 1721.892123 574.9689 Alpha-mannosidase 2 OS=Homo sapiens OX=9606 GN=MAN2A1 PE=1 SV=2 6.92 2542.6 - 982207 - - - 4.1844 - 2.638 0.499 - 128.8 1 2 0 0.0072 16 0 0 0 8.84E+06 1.19E+07 - - - 6.5903 0.9998 221125_WJC_METTL3_EV_vs_WT_F06.14757.14757.3 1.16E-05 13/52 R.STAYEDYYYHPPPR.M "sp|O43390|HNRPR_HUMAN,tr|B4DT28|B4DT28_HUMAN,tr|A0A6Q8PH35|A0A6Q8PH35_HUMAN,tr|A0A286YEZ8|A0A286YEZ8_HUMAN" 4 1757.7686 1.46 83843 14757 3 1757.774687 586.9301 Heterogeneous nuclear ribonucleoprotein R OS=Homo sapiens OX=9606 GN=HNRNPR PE=1 SV=1 5.3 2542.9 - 1.23E+06 - - - 3.4914 - 2.233 0.497 - 164.6 1 2 0 0.0061 14 0 0 0 2.97E+07 2.04E+07 - - - 6.2143 1 221125_WJC_METTL3_EV_vs_WT_F06.14758.14758.3 1.65E-05 Dec-40 K.HIYFINC[160.03]GDSR.A "sp|O75688|PPM1B_HUMAN,tr|B8ZZF0|B8ZZF0_HUMAN,tr|A0A3B3IS24|A0A3B3IS24_HUMAN,tr|C9JIR6|C9JIR6_HUMAN" 4 1380.6245 2.81 83844 14758 3 1380.626375 461.2154 Protein phosphatase 1B OS=Homo sapiens OX=9606 GN=PPM1B PE=1 SV=1 6.73 2543.1 - 507225 - - - 1.3805 - 2.002 0.53 - 284.3 1 2 0 0.0019 11 0 0 0 4.07E+08 1.45E+08 - - - 6.4204 0.9998 221125_WJC_METTL3_EV_vs_WT_F06.14763.14763.2 1.90E-05 30-Nov K.SQLLAPPPPSAPPGNK.T "sp|P49750|YLPM1_HUMAN,tr|F8VU51|F8VU51_HUMAN" 2 1569.8515 5.92 83848 14763 2 1569.852666 785.933 YLP motif-containing protein 1 OS=Homo sapiens OX=9606 GN=YLPM1 PE=1 SV=4 8.47 2543.7 - 500783 - - - 0.7478 - 2.228 0.509 - 321 1 2 0 0.0012 16 0 0 0 1.19E+07 2.01E+06 - - - 4.7697 1 221125_WJC_METTL3_EV_vs_WT_F06.14766.14766.2 4.80E-08 19/30 R.EALLSSAVDHGSDEVK[136.11].F "sp|P78371|TCPB_HUMAN,tr|F8VQ14|F8VQ14_HUMAN,tr|F5GWF6|F5GWF6_HUMAN" 3 1663.8144 0.61 83850 14766 2 1663.814295 832.9145 T-complex protein 1 subunit beta OS=Homo sapiens OX=9606 GN=CCT2 PE=1 SV=4 4.31 2544 - 2.61E+06 - - - -0.0902 - 3.486 0.66 - 1064.8 1 2 0 -0.0001 16 0 0 0 7.83E+07 1.28E+08 - - - 6.9858 1 221125_WJC_METTL3_EV_vs_WT_F06.14769.14769.3 1.51E-05 Nov-40 K.HIYFINC[160.03]GDSR[166.11].A "sp|O75688|PPM1B_HUMAN,tr|B8ZZF0|B8ZZF0_HUMAN,tr|A0A3B3IS24|A0A3B3IS24_HUMAN,tr|C9JIR6|C9JIR6_HUMAN" 4 1390.6327 2.88 83853 14769 3 1390.634983 464.5515 Protein phosphatase 1B OS=Homo sapiens OX=9606 GN=PPM1B PE=1 SV=1 6.73 2544.1 - 952127 - - - 1.6137 - 1.856 0.568 - 194.4 1 2 0 0.0022 11 0 0 0 4.04E+08 1.40E+08 - - - 6.6288 0.9998 221125_WJC_METTL3_EV_vs_WT_F06.14771.14771.3 3.11E-05 Dec-36 K.K[136.11]SDVEAIFSK[136.11].Y "sp|P0DMR1|HNRC4_HUMAN,sp|P07910|HNRPC_HUMAN,sp|O60812|HNRC1_HUMAN,sp|B2RXH8|HNRC2_HUMAN,sp|B7ZW38|HNRC3_HUMAN,tr|G3V251|G3V251_HUMAN,tr|B4DY08|B4DY08_HUMAN,tr|G3V575|G3V575_HUMAN,tr|B4DSU6|B4DSU6_HUMAN,tr|G3V3K6|G3V3K6_HUMAN,tr|B2R5W2|B2R5W2_HUMAN,tr|G3V4C1|G3V4C1_HUMAN,tr|A0A0G2JPF8|A0A0G2JPF8_HUMAN,tr|A0A0G2JNQ3|A0A0G2JNQ3_HUMAN,tr|G3V576|G3V576_HUMAN,tr|G3V5X6|G3V5X6_HUMAN,tr|G3V2H6|G3V2H6_HUMAN,tr|G3V4W0|G3V4W0_HUMAN,tr|G3V555|G3V555_HUMAN,tr|G3V4M8|G3V4M8_HUMAN,tr|G3V2Q1|G3V2Q1_HUMAN" 21 1138.6205 0.001 83855 14771 3 1138.621259 380.5474 Heterogeneous nuclear ribonucleoprotein C-like 4 OS=Homo sapiens OX=9606 GN=HNRNPCL4 PE=3 SV=1 6.07 2544.4 - 412492 - - - 0.6754 - 2.404 0.325 - 238 1 2 0 0.0008 10 0 0 0 0.00E+00 7.63E+07 - - - 4.7248 1 221125_WJC_METTL3_EV_vs_WT_F06.14775.14775.3 2.01E-10 18/60 R.EALLSSAVDHGSDEVK[136.11].F "sp|P78371|TCPB_HUMAN,tr|F8VQ14|F8VQ14_HUMAN,tr|F5GWF6|F5GWF6_HUMAN" 3 1663.8144 0.52 83857 14775 3 1663.811756 555.6121 T-complex protein 1 subunit beta OS=Homo sapiens OX=9606 GN=CCT2 PE=1 SV=4 4.31 2544.9 - 5.09E+07 - - - -1.6162 - 3.791 0.595 - 666.5 1 2 0 -0.0027 16 0 0 0 6.78E+08 1.30E+09 - - - 8.5923 0.9988 221125_WJC_METTL3_EV_vs_WT_F06.14776.14776.2 0.0101 24-Aug K.GGSGSGPTIEEVD.- "sp|P0DMV8|HS71A_HUMAN,sp|P0DMV9|HS71B_HUMAN,tr|V9GZ37|V9GZ37_HUMAN,tr|A0A0G2JIW1|A0A0G2JIW1_HUMAN" 4 1203.5255 - 83858 14776 2 1203.526863 602.77 Heat shock 70 kDa protein 1A OS=Homo sapiens OX=9606 GN=HSPA1A PE=1 SV=1 3.88 2545 - 2.62E+06 - - - 1.1109 - 1.581 0.314 - 144.7 1 2 0 0.0013 13 0 0 0 - - - - - 2.5354 1 221125_WJC_METTL3_EV_vs_WT_F06.14777.14777.3 2.72E-09 24/76 R.QGAIVAVTGDGVNDSPALK[136.11]K[136.11].A "sp|P05023|AT1A1_HUMAN,sp|P13637|AT1A3_HUMAN,sp|P50993|AT1A2_HUMAN,tr|A0A0A0MT26|A0A0A0MT26_HUMAN,tr|H0Y7C1|H0Y7C1_HUMAN,tr|A0A2R8YEY8|A0A2R8YEY8_HUMAN,tr|B1AKY9|B1AKY9_HUMAN,tr|M0R116|M0R116_HUMAN" 8 1955.0659 1.24 83859 14777 3 1955.068184 652.6959 Sodium\potassium-transporting ATPase subunit alpha-1 OS=Homo sapiens OX=9606 GN=ATP1A1 PE=1 SV=1 5.96 2545.1 - 1.73E+06 - - - 1.1913 - 4.168 0.609 - 723.3 1 2 0 0.0023 20 0 0 0 5.99E+07 4.83E+07 - - - 8.7921 1 221125_WJC_METTL3_EV_vs_WT_F06.14779.14779.3 3.63E-06 14/40 K.SDDVLHDLGQK.E "sp|Q9BVV6|TALD3_HUMAN,tr|A0A087WYM5|A0A087WYM5_HUMAN,tr|A0A494C0M8|A0A494C0M8_HUMAN,tr|A0A494C075|A0A494C075_HUMAN,tr|A0A494C0Z1|A0A494C0Z1_HUMAN,tr|A0A494C171|A0A494C171_HUMAN" 6 1225.5939 3.4 83861 14779 3 1225.594769 409.5386 Protein TALPID3 OS=Homo sapiens OX=9606 GN=KIAA0586 PE=1 SV=4 4.41 2545.3 - 576110 - - - 0.7245 - 2.534 0.489 - 255.9 1 2 0 0.0009 11 0 0 0 3.98E+07 1.17E+07 - - - 6.633 0.9999 221125_WJC_METTL3_EV_vs_WT_F06.14781.14781.3 3.79E-05 13/56 K.K[136.11]AEAGAGSATEFQFR[166.11].G "sp|Q9NQ39|RS10L_HUMAN,sp|P46783|RS10_HUMAN" 2 1586.7808 1.15 83863 14781 3 1586.780435 529.9342 Putative 40S ribosomal protein S10-like OS=Homo sapiens OX=9606 GN=RPS10P5 PE=5 SV=1 6.14 2545.5 - 543513 - - - -0.2237 - 2.533 0.357 - 226.5 1 2 0 -0.0004 15 0 0 0 1.61E+07 1.40E+07 - - - 4.9453 0.9997 221125_WJC_METTL3_EV_vs_WT_F06.14787.14787.3 0.000237 14/76 R.QGAIVAVTGDGVNDSPALKK.A "sp|P05023|AT1A1_HUMAN,sp|P13637|AT1A3_HUMAN,sp|P50993|AT1A2_HUMAN,tr|A0A0A0MT26|A0A0A0MT26_HUMAN,tr|H0Y7C1|H0Y7C1_HUMAN,tr|A0A2R8YEY8|A0A2R8YEY8_HUMAN,tr|B1AKY9|B1AKY9_HUMAN,tr|M0R116|M0R116_HUMAN" 8 1939.0375 1.25 83867 14787 3 1939.044565 647.3531 Sodium\potassium-transporting ATPase subunit alpha-1 OS=Homo sapiens OX=9606 GN=ATP1A1 PE=1 SV=1 5.96 2546.3 - 2.60E+06 - - - 3.6668 - 2.752 0.432 - 203.1 1 2 0 0.0071 20 0 0 0 6.05E+07 4.83E+07 - - - 5.8103 0.9998 221125_WJC_METTL3_EV_vs_WT_F06.14788.14788.2 2.69E-07 20-Nov K.HIYFINC[160.03]GDSR.A "sp|O75688|PPM1B_HUMAN,tr|B8ZZF0|B8ZZF0_HUMAN,tr|A0A3B3IS24|A0A3B3IS24_HUMAN,tr|C9JIR6|C9JIR6_HUMAN" 4 1380.6245 3.13 83868 14788 2 1380.62672 691.3195 Protein phosphatase 1B OS=Homo sapiens OX=9606 GN=PPM1B PE=1 SV=1 6.73 2546.4 - 2.56E+06 - - - 1.6304 - 2.112 0.547 - 356 1 2 0 0.0023 11 0 0 0 1.52E+08 4.85E+07 - - - 5.103 0.9803 221125_WJC_METTL3_EV_vs_WT_F06.14791.14791.3 0.0727 Nov-48 K.SVEEGKIDGIIDK.T sp|Q96A49|SYAP1_HUMAN 1 1401.7351 1.2 83871 14791 3 1401.738437 468.2523 Synapse-associated protein 1 OS=Homo sapiens OX=9606 GN=SYAP1 PE=1 SV=1 4.32 2546.8 - 496654 - - - 2.3628 - 1.856 0.242 - 95.1 1 2 1 0.0033 13 0 0 0 1.08E+07 9.04E+06 - - - 2.9139 0.9999 221125_WJC_METTL3_EV_vs_WT_F06.14792.14792.3 4.50E-07 13/40 K.SDDVLHDLGQK[136.11].E "sp|Q9BVV6|TALD3_HUMAN,tr|A0A087WYM5|A0A087WYM5_HUMAN,tr|A0A494C0M8|A0A494C0M8_HUMAN,tr|A0A494C075|A0A494C075_HUMAN,tr|A0A494C0Z1|A0A494C0Z1_HUMAN,tr|A0A494C171|A0A494C171_HUMAN" 6 1233.6081 3.4 83872 14792 3 1233.610414 412.21 Protein TALPID3 OS=Homo sapiens OX=9606 GN=KIAA0586 PE=1 SV=4 4.41 2546.9 - 480537 - - - 1.8912 - 2.173 0.493 - 253.7 1 2 0 0.0023 11 0 0 0 3.98E+07 1.17E+07 - - - 6.2406 0.999 221125_WJC_METTL3_EV_vs_WT_F06.14793.14793.3 0.000449 Oct-60 R.VFDK[136.11]EGNGTVMGAELR[166.11].H "sp|P08590|MYL3_HUMAN,sp|P05976|MYL1_HUMAN,sp|P60660|MYL6_HUMAN,tr|F8W1R7|F8W1R7_HUMAN,tr|G3V1V0|G3V1V0_HUMAN,tr|B7Z6Z4|B7Z6Z4_HUMAN,tr|F8VZU9|F8VZU9_HUMAN,tr|G8JLA2|G8JLA2_HUMAN,tr|H0YI43|H0YI43_HUMAN,tr|F8W180|F8W180_HUMAN,tr|G3V1Y7|G3V1Y7_HUMAN,tr|J3KND3|J3KND3_HUMAN,tr|F8VPF3|F8VPF3_HUMAN" 13 1739.8631 7.21 83873 14793 3 1739.862746 580.9617 Myosin light chain 3 OS=Homo sapiens OX=9606 GN=MYL3 PE=1 SV=3 4.68 2547 - 432617 - - - -0.2265 - 1.889 0.389 - 102.2 1 2 1 -0.0004 16 0 0 0 4.75E+07 6.59E+06 - - - 4.5089 0.9995 221125_WJC_METTL3_EV_vs_WT_F06.14794.14794.4 0.0305 14/72 R.VIAHPSFHNINFK[136.11].Q sp|Q7KZ85|SPT6H_HUMAN 1 1530.8187 1.28 83874 14794 4 1530.817786 383.7119 Transcription elongation factor SPT6 OS=Homo sapiens OX=9606 GN=SUPT6H PE=1 SV=2 8.74 2547.2 - 415629 - - - -0.5853 - 2.326 0.322 - 145.9 1 2 0 -0.0009 13 0 0 0 1.59E+07 1.25E+07 - - - 2.3414 0.9703 221125_WJC_METTL3_EV_vs_WT_F06.14797.14797.3 0.122 Oct-60 K.VNTKPC[160.03]SLPGYLPPTK.N sp|O75925|PIAS1_HUMAN 1 1770.9338 1.1 83875 14797 3 1770.940152 591.3186 E3 SUMO-protein ligase PIAS1 OS=Homo sapiens OX=9606 GN=PIAS1 PE=1 SV=2 9.2 2547.6 - 922121 - - - 3.5631 - 1.742 0.201 - 97.4 1 2 0 0.0063 16 0 0 0 2.24E+07 2.03E+07 - - - 2.2033 1 221125_WJC_METTL3_EV_vs_WT_F06.14800.14800.3 0.00183 16/44 R.TFIAIK[136.11]PDGVQR[166.11].G "sp|P15531|NDKA_HUMAN,sp|P22392|NDKB_HUMAN,tr|Q32Q12|Q32Q12_HUMAN,tr|Q32Q12|Q32Q12_HUMAN,tr|J3KPD9|J3KPD9_HUMAN,tr|F6XY72|F6XY72_HUMAN,tr|E5RHP0|E5RHP0_HUMAN,tr|E7ERL0|E7ERL0_HUMAN,tr|C9K028|C9K028_HUMAN" 9 1361.7786 1.4 83878 14800 3 1361.779189 454.9335 Nucleoside diphosphate kinase A OS=Homo sapiens OX=9606 GN=NME1 PE=1 SV=1 8.41 2547.8 - 869096 - - - 0.4289 - 2.394 0.481 - 302.5 1 2 0 0.0006 12 0 0 0 4.55E+07 3.24E+07 - - - 6.3222 1 221125_WJC_METTL3_EV_vs_WT_F06.14803.14803.3 1.58E-07 Dec-44 R.TFIAIKPDGVQR.G "sp|P15531|NDKA_HUMAN,sp|P22392|NDKB_HUMAN,tr|Q32Q12|Q32Q12_HUMAN,tr|Q32Q12|Q32Q12_HUMAN,tr|J3KPD9|J3KPD9_HUMAN,tr|F6XY72|F6XY72_HUMAN,tr|E5RHP0|E5RHP0_HUMAN,tr|E7ERL0|E7ERL0_HUMAN,tr|C9K028|C9K028_HUMAN" 9 1343.7561 1.44 83881 14803 3 1343.757653 448.926 Nucleoside diphosphate kinase A OS=Homo sapiens OX=9606 GN=NME1 PE=1 SV=1 8.41 2548.2 - 595889 - - - 1.1297 - 2.494 0.472 - 171.8 1 2 0 0.0015 12 0 0 0 4.81E+07 3.34E+07 - - - 6.3351 0.9931 221125_WJC_METTL3_EV_vs_WT_F06.14806.14806.2 0.0666 28-Jun R.VQPQWSPPAGTQPC[160.03]R[166.11].L "sp|P49589|SYCC_HUMAN,tr|B4DKY1|B4DKY1_HUMAN,tr|C9JLN0|C9JLN0_HUMAN,tr|E9PRS8|E9PRS8_HUMAN,tr|E9PLP0|E9PLP0_HUMAN" 5 1717.8234 -1 83884 14806 2 1717.827363 859.919 "Cysteine--tRNA ligase, cytoplasmic OS=Homo sapiens OX=9606 GN=CARS1 PE=1 SV=3" 8.22 2548.6 - 254748 - - - 2.3105 - 1.25 0.277 - 60.4 1 2 0 0.004 15 0 0 0 0.00E+00 0.00E+00 - - - 1.6343 0.9986 221125_WJC_METTL3_EV_vs_WT_F06.14811.14811.3 0.00338 Oct-48 K.SVEEGK[136.11]IDGIIDK[136.11].T sp|Q96A49|SYAP1_HUMAN 1 1417.7635 1.17 83887 14811 3 1417.764118 473.5951 Synapse-associated protein 1 OS=Homo sapiens OX=9606 GN=SYAP1 PE=1 SV=1 4.32 2549.2 - 515485 - - - 0.4183 - 1.962 0.347 - 78.3 1 2 1 0.0006 13 0 0 0 8.15E+06 6.94E+06 - - - 4.2359 0.9997 221125_WJC_METTL3_EV_vs_WT_F06.14815.14815.2 0.000306 16-Nov K.SPLQSVVVR.R "sp|Q9Y2W1|TR150_HUMAN,tr|A0A3B3ITZ9|A0A3B3ITZ9_HUMAN" 2 983.5764 2.91 83889 14815 2 983.577919 492.7955 Thyroid hormone receptor-associated protein 3 OS=Homo sapiens OX=9606 GN=THRAP3 PE=1 SV=2 9.47 2549.7 - 949792 - - - 1.5647 - 1.96 0.437 - 321.5 1 2 0 0.0015 9 0 0 0 3.13E+07 1.08E+07 - - - 4.2151 1 221125_WJC_METTL3_EV_vs_WT_F06.14819.14819.2 2.36E-05 15/26 R.AQVQEFC[160.03]DYGTK[136.11]EE.C "sp|Q86U44|MTA70_HUMAN,tr|H0YFV6|H0YFV6_HUMAN" 2 1710.7287 0.01 83893 14819 2 1710.728623 856.3716 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 4.24 2550 - 1.31E+06 - - - -0.0251 - 2.868 0.691 - 503.2 1 1 1 0 14 0 0 0 2.12E+05 2.08E+07 - - - 6.7887 1 221125_WJC_METTL3_EV_vs_WT_F06.14822.14822.3 5.58E-06 16/60 R.LAQMISDHNDADFEEK.V "sp|Q14157|UBP2L_HUMAN,tr|Q5VU78|Q5VU78_HUMAN,tr|F8W726|F8W726_HUMAN,tr|Q5VU81|Q5VU81_HUMAN,tr|Q5VU79|Q5VU79_HUMAN,tr|Q5VU80|Q5VU80_HUMAN,tr|Q5VU77|Q5VU77_HUMAN" 7 1861.8152 2.45 83896 14822 3 1861.814186 621.6124 Ubiquitin-associated protein 2-like OS=Homo sapiens OX=9606 GN=UBAP2L PE=1 SV=2 4.1 2550.4 - 570607 - - - -0.5677 - 2.783 0.462 - 195.5 1 2 0 -0.0011 16 0 0 0 5.51E+08 2.25E+08 - - - 6.3168 0.9999 221125_WJC_METTL3_EV_vs_WT_F06.14825.14825.2 0.502 15/18 K.KSDVEAIFSK.Y "sp|P0DMR1|HNRC4_HUMAN,sp|P07910|HNRPC_HUMAN,sp|O60812|HNRC1_HUMAN,sp|B2RXH8|HNRC2_HUMAN,sp|B7ZW38|HNRC3_HUMAN,tr|G3V251|G3V251_HUMAN,tr|B4DY08|B4DY08_HUMAN,tr|G3V575|G3V575_HUMAN,tr|B4DSU6|B4DSU6_HUMAN,tr|G3V3K6|G3V3K6_HUMAN,tr|B2R5W2|B2R5W2_HUMAN,tr|G3V4C1|G3V4C1_HUMAN,tr|A0A0G2JPF8|A0A0G2JPF8_HUMAN,tr|A0A0G2JNQ3|A0A0G2JNQ3_HUMAN,tr|G3V576|G3V576_HUMAN,tr|G3V5X6|G3V5X6_HUMAN,tr|G3V2H6|G3V2H6_HUMAN,tr|G3V4W0|G3V4W0_HUMAN,tr|G3V555|G3V555_HUMAN,tr|G3V4M8|G3V4M8_HUMAN,tr|G3V2Q1|G3V2Q1_HUMAN" 21 1122.5921 1.24 83898 14825 2 1122.59354 562.3033 Heterogeneous nuclear ribonucleoprotein C-like 4 OS=Homo sapiens OX=9606 GN=HNRNPCL4 PE=3 SV=1 6.07 2550.8 - 1.13E+07 - - - 1.2917 - 3.104 0.465 - 712.7 1 2 0 0.0014 10 0 0 0 1.56E+08 1.26E+08 - - - 5.6367 0.9999 221125_WJC_METTL3_EV_vs_WT_F06.14827.14827.3 0.000432 13/52 K.K[136.11]VEEAEPEEFVVEK[136.11].V "sp|Q13185|CBX3_HUMAN,tr|C9JMM0|C9JMM0_HUMAN,tr|S4R2Y4|S4R2Y4_HUMAN,tr|B8ZZ43|B8ZZ43_HUMAN" 4 1676.848 6.45 83899 14827 3 1676.852233 559.9566 Chromobox protein homolog 3 OS=Homo sapiens OX=9606 GN=CBX3 PE=1 SV=4 4.21 2551 - 1.18E+07 - - - 2.5345 - 2.82 0.457 - 363.7 1 2 0 0.0043 14 0 0 0 1.25E+09 1.93E+08 - - - 6.3891 1 221125_WJC_METTL3_EV_vs_WT_F06.14829.14829.3 7.20E-10 22/48 R.GISHVIVDEIHER[166.11].D sp|Q08211|DHX9_HUMAN 1 1512.7924 1.03 83901 14829 3 1512.793519 505.2714 ATP-dependent RNA helicase A OS=Homo sapiens OX=9606 GN=DHX9 PE=1 SV=4 5.27 2551.2 - 3.62E+06 - - - 0.7324 - 3.648 0.563 - 1088 1 2 0 0.0011 13 0 0 0 1.97E+08 1.92E+08 - - - 8.3255 0.9998 221125_WJC_METTL3_EV_vs_WT_F06.14831.14831.3 0.000635 Dec-36 R.K[136.11]HALFPELPK[136.11].S sp|Q96JM3|CHAP1_HUMAN 1 1194.7096 0.76 83903 14831 3 1194.709686 399.2438 Chromosome alignment-maintaining phosphoprotein 1 OS=Homo sapiens OX=9606 GN=CHAMP1 PE=1 SV=2 8.6 2551.5 - 611110 - - - 0.0896 - 1.968 0.374 - 181.7 1 2 0 0.0001 10 0 0 0 9.83E+06 1.30E+07 - - - 4.6869 0.9906 221125_WJC_METTL3_EV_vs_WT_F06.14832.14832.4 2.36E-09 22/84 Y.LLSSAYVDSHKWEAR.E "sp|Q92552|RT27_HUMAN,tr|E5RJ73|E5RJ73_HUMAN" 2 1760.8846 1.06 83904 14832 4 1760.885415 441.2284 "28S ribosomal protein S27, mitochondrial OS=Homo sapiens OX=9606 GN=MRPS27 PE=1 SV=3" 6.75 2551.6 - 484874 - - - 0.4725 - 3.625 0.545 - 467.8 1 1 1 0.0008 15 0 0 0 1.63E+07 1.54E+07 - - - 4.4303 1 221125_WJC_METTL3_EV_vs_WT_F06.14834.14834.2 1.61E-08 14/30 R.EPSVPASC[160.03]AVSATYER.S "sp|Q92615|LAR4B_HUMAN,tr|H0Y641|H0Y641_HUMAN,tr|H0Y4V9|H0Y4V9_HUMAN" 3 1722.7883 1.06 83906 14834 2 1722.778529 862.4014 La-related protein 4B OS=Homo sapiens OX=9606 GN=LARP4B PE=1 SV=3 4.53 2551.9 - 360285 - - - -5.6716 - 2.556 0.593 - 323 1 2 0 -0.0098 16 0 0 0 1.01E+07 9.54E+06 - - - 5.725 0.9999 221125_WJC_METTL3_EV_vs_WT_F06.14837.14837.2 1.53E-06 17/18 K.K[136.11]SDVEAIFSK[136.11].Y "sp|P0DMR1|HNRC4_HUMAN,sp|P07910|HNRPC_HUMAN,sp|O60812|HNRC1_HUMAN,sp|B2RXH8|HNRC2_HUMAN,sp|B7ZW38|HNRC3_HUMAN,tr|G3V251|G3V251_HUMAN,tr|B4DY08|B4DY08_HUMAN,tr|G3V575|G3V575_HUMAN,tr|B4DSU6|B4DSU6_HUMAN,tr|G3V3K6|G3V3K6_HUMAN,tr|B2R5W2|B2R5W2_HUMAN,tr|G3V4C1|G3V4C1_HUMAN,tr|A0A0G2JPF8|A0A0G2JPF8_HUMAN,tr|A0A0G2JNQ3|A0A0G2JNQ3_HUMAN,tr|G3V576|G3V576_HUMAN,tr|G3V5X6|G3V5X6_HUMAN,tr|G3V2H6|G3V2H6_HUMAN,tr|G3V4W0|G3V4W0_HUMAN,tr|G3V555|G3V555_HUMAN,tr|G3V4M8|G3V4M8_HUMAN,tr|G3V2Q1|G3V2Q1_HUMAN" 21 1138.6205 1.37 83907 14837 2 1138.621268 570.3175 Heterogeneous nuclear ribonucleoprotein C-like 4 OS=Homo sapiens OX=9606 GN=HNRNPCL4 PE=3 SV=1 6.07 2552.3 - 7.19E+06 - - - 0.6833 - 3.114 0.428 - 961.3 1 2 0 0.0008 10 0 0 0 1.55E+08 1.13E+08 - - - 5.3726 1 221125_WJC_METTL3_EV_vs_WT_F06.14838.14838.2 1.56E-07 13/20 K.HIYFINC[160.03]GDSR[166.11].A "sp|O75688|PPM1B_HUMAN,tr|B8ZZF0|B8ZZF0_HUMAN,tr|A0A3B3IS24|A0A3B3IS24_HUMAN,tr|C9JIR6|C9JIR6_HUMAN" 4 1390.6327 3.16 83908 14838 2 1390.632989 696.3236 Protein phosphatase 1B OS=Homo sapiens OX=9606 GN=PPM1B PE=1 SV=1 6.73 2552.4 - 2.28E+06 - - - 0.1798 - 2.392 0.653 - 445.5 1 2 0 0.0003 11 0 0 0 1.49E+08 4.70E+07 - - - 6.2233 0.9943 221125_WJC_METTL3_EV_vs_WT_F06.14839.14839.2 2.01E-07 13/28 R.R[166.11]AEQDSTTVAAFASS.L "sp|Q86U44|MTA70_HUMAN,tr|F5H6D8|F5H6D8_HUMAN,tr|H0YFV6|H0YFV6_HUMAN,tr|B4DTN4|B4DTN4_HUMAN" 4 1549.7248 0.03 83909 14839 2 1549.723875 775.8697 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 4.37 2552.4 - 4.46E+06 - - - -0.5872 - 2.154 0.608 - 338.9 1 1 0 -0.0009 15 0 0 0 1.52E+07 5.06E+08 - - - 5.4179 1 221125_WJC_METTL3_EV_vs_WT_F06.14842.14842.2 1.11E-08 14/30 R.EPSVPASC[160.03]AVSATYER[166.11].S "sp|Q92615|LAR4B_HUMAN,tr|H0Y641|H0Y641_HUMAN,tr|H0Y4V9|H0Y4V9_HUMAN" 3 1732.7966 1.06 83912 14842 2 1732.797512 867.4056 La-related protein 4B OS=Homo sapiens OX=9606 GN=LARP4B PE=1 SV=3 4.53 2552.8 - 447332 - - - 0.5436 - 2.628 0.658 - 379.9 1 2 0 0.0009 16 0 0 0 1.01E+07 9.54E+06 - - - 6.2762 0.7935 221125_WJC_METTL3_EV_vs_WT_F06.14848.14848.4 8.58E-06 16/84 Y.LLSSAYVDSHK[136.11]WEAR[166.11].E "sp|Q92552|RT27_HUMAN,tr|E5RJ73|E5RJ73_HUMAN" 2 1778.9071 1.06 83916 14848 4 1778.908202 445.734 "28S ribosomal protein S27, mitochondrial OS=Homo sapiens OX=9606 GN=MRPS27 PE=1 SV=3" 6.75 2553.4 - 1.49E+06 - - - 0.6459 - 2.604 0.316 - 181.6 1 1 1 0.0011 15 0 0 0 1.64E+07 1.54E+07 - - - 2.3186 0.944 221125_WJC_METTL3_EV_vs_WT_F06.14853.14853.3 0.0343 Dec-48 R.ETLEDGFPVHDGK.G "sp|P30519|HMOX2_HUMAN,tr|A0A087WT44|A0A087WT44_HUMAN,tr|I3L1Y2|I3L1Y2_HUMAN" 3 1442.6678 1.5 83921 14853 3 1442.665166 481.8965 Heme oxygenase 2 OS=Homo sapiens OX=9606 GN=HMOX2 PE=1 SV=2 4.31 2553.9 - 1.14E+06 - - - -1.8078 - 1.762 0.087 - 108.1 1 2 0 -0.0026 13 0 0 0 1.18E+07 7.87E+06 - - - 1.0451 1 221125_WJC_METTL3_EV_vs_WT_F06.14854.14854.4 3.09E-07 15/96 R.LASALAPSIYEHEDIK[136.11]K[136.11].G "sp|P33991|MCM4_HUMAN,tr|A0A3B3IT92|A0A3B3IT92_HUMAN,tr|A0A3B3IU45|A0A3B3IU45_HUMAN,tr|A0A3B3ITP6|A0A3B3ITP6_HUMAN,tr|A0A3B3IRR8|A0A3B3IRR8_HUMAN,tr|E5RG31|E5RG31_HUMAN,tr|A0A3B3IS57|A0A3B3IS57_HUMAN" 7 1900.0277 0.84 83922 14854 4 1900.029606 476.0142 DNA replication licensing factor MCM4 OS=Homo sapiens OX=9606 GN=MCM4 PE=1 SV=5 5.45 2554 - 921705 - - - 1.0142 - 3.204 0.504 - 167 1 2 0 0.0019 17 0 0 0 1.18E+07 1.40E+07 - - - 4.0166 0.9999 221125_WJC_METTL3_EV_vs_WT_F06.14855.14855.4 4.57E-06 19/96 R.LASALAPSIYEHEDIKK.G "sp|P33991|MCM4_HUMAN,tr|A0A3B3IT92|A0A3B3IT92_HUMAN,tr|A0A3B3IU45|A0A3B3IU45_HUMAN,tr|A0A3B3ITP6|A0A3B3ITP6_HUMAN,tr|A0A3B3IRR8|A0A3B3IRR8_HUMAN,tr|E5RG31|E5RG31_HUMAN,tr|A0A3B3IS57|A0A3B3IS57_HUMAN" 7 1883.9993 0.84 83923 14855 4 1884.000882 472.0071 DNA replication licensing factor MCM4 OS=Homo sapiens OX=9606 GN=MCM4 PE=1 SV=5 5.45 2554.1 - 734029 - - - 0.8508 - 3.321 0.432 - 333.8 1 2 0 0.0016 17 0 0 0 1.18E+07 1.40E+07 - - - 3.4024 0.9997 221125_WJC_METTL3_EV_vs_WT_F06.14856.14856.3 4.84E-07 18/64 K.AVTPPVKDDNEDVFSAR.L sp|Q5VT06|CE350_HUMAN 1 1858.9061 2.06 83924 14856 3 1858.911116 620.6426 Centrosome-associated protein 350 OS=Homo sapiens OX=9606 GN=CEP350 PE=1 SV=1 4.23 2554.2 - 733884 - - - 2.6946 - 3.343 0.502 - 467.9 1 2 1 0.005 17 0 0 0 9.59E+07 4.66E+07 - - - 7.1843 0.9868 221125_WJC_METTL3_EV_vs_WT_F06.14861.14861.4 0.0268 13/84 R.STSHK[136.11]PDEIYGMIER[166.11].L sp|Q86U44|MTA70_HUMAN 1 1779.8581 0.001 83927 14861 4 1779.855263 445.9718 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 5.42 2554.8 - 2.13E+06 - - - -1.5681 - 1.881 0.19 - 95.4 1 2 0 -0.0028 15 0 0 0 0.00E+00 1.01E+08 - - - 1.1051 1 221125_WJC_METTL3_EV_vs_WT_F06.14862.14862.3 1.09E-07 21/48 R.GISHVIVDEIHER.D sp|Q08211|DHX9_HUMAN 1 1502.7841 1.01 83928 14862 3 1502.784821 501.9353 ATP-dependent RNA helicase A OS=Homo sapiens OX=9606 GN=DHX9 PE=1 SV=4 5.27 2554.8 - 1.44E+07 - - - 0.4525 - 3.76 0.594 - 923.5 1 2 0 0.0007 13 0 0 0 1.93E+08 1.91E+08 - - - 8.7532 0.9998 221125_WJC_METTL3_EV_vs_WT_F06.14863.14863.2 1.18E-06 13/26 R.SLYASSPGGVYATR.S "sp|P08670|VIME_HUMAN,tr|B0YJC4|B0YJC4_HUMAN,tr|A0A1B0GVG8|A0A1B0GVG8_HUMAN,tr|A0A1B0GTT5|A0A1B0GTT5_HUMAN" 4 1427.7045 1.54 83929 14863 2 1427.702224 714.8595 Vimentin OS=Homo sapiens OX=9606 GN=VIM PE=1 SV=4 8.31 2554.9 - 1.26E+06 - - - -1.59 - 2.388 0.548 - 473.3 1 2 0 -0.0023 14 0 0 0 6.37E+07 4.13E+07 - - - 5.2722 0.9419 221125_WJC_METTL3_EV_vs_WT_F06.14865.14865.3 6.88E-06 18/64 A.AQNAAVQAVNAHSNILK.A "sp|Q16891|MIC60_HUMAN,tr|B9A067|B9A067_HUMAN,tr|C9J406|C9J406_HUMAN,tr|H7C463|H7C463_HUMAN" 4 1747.9329 1.2 83931 14865 3 1747.941982 583.6516 MICOS complex subunit MIC60 OS=Homo sapiens OX=9606 GN=IMMT PE=1 SV=1 8.8 2555.1 - 1.02E+06 - - - 5.1787 - 2.816 0.476 - 243.3 1 1 0 0.0091 17 0 0 0 1.46E+07 1.22E+07 - - - 6.4599 1 221125_WJC_METTL3_EV_vs_WT_F06.14866.14866.2 3.87E-06 17/24 R.GISHVIVDEIHER[166.11].D sp|Q08211|DHX9_HUMAN 1 1512.7924 0.98 83932 14866 2 1512.794816 757.4035 ATP-dependent RNA helicase A OS=Homo sapiens OX=9606 GN=DHX9 PE=1 SV=4 5.27 2555.3 - 969775 - - - 1.5898 - 3.155 0.507 - 1046.2 1 2 0 0.0024 13 0 0 0 1.35E+07 1.37E+07 - - - 5.7339 1 221125_WJC_METTL3_EV_vs_WT_F06.14867.14867.2 4.17E-07 16/24 R.GISHVIVDEIHER.D sp|Q08211|DHX9_HUMAN 1 1502.7841 0.98 83933 14867 2 1502.780947 752.3993 ATP-dependent RNA helicase A OS=Homo sapiens OX=9606 GN=DHX9 PE=1 SV=4 5.27 2555.4 - 905969 - - - -2.1254 - 2.978 0.589 - 920.4 1 2 0 -0.0032 13 0 0 0 1.35E+07 1.37E+07 - - - 6.1911 0.9522 221125_WJC_METTL3_EV_vs_WT_F06.14868.14868.4 0.0486 13/108 R.VLEEYSVPC[160.03]AHAAHVTGLK[136.11].L "sp|Q9NNW5|WDR6_HUMAN,tr|E9PBK6|E9PBK6_HUMAN,tr|E9PDU5|E9PDU5_HUMAN,tr|Q6PKC6|Q6PKC6_HUMAN,tr|A0A087X295|A0A087X295_HUMAN" 5 2088.0554 1.09 83934 14868 4 2088.061531 523.0211 WD repeat-containing protein 6 OS=Homo sapiens OX=9606 GN=WDR6 PE=1 SV=1 6 2555.5 - 857687 - - - 2.9549 - 2.533 0.194 - 90.8 2 2 0 0.0062 19 0 0 0 5.51E+06 5.06E+06 - - - 0.9978 1 221125_WJC_METTL3_EV_vs_WT_F06.14869.14869.3 2.02E-07 16/52 R.GGNNSFTHEALTLK.Y sp|P08240|SRPRA_HUMAN 1 1487.7369 1.88 83935 14869 3 1487.738449 496.9196 Signal recognition particle receptor subunit alpha OS=Homo sapiens OX=9606 GN=SRPRA PE=1 SV=2 6.75 2555.6 - 830464 - - - 1.0708 - 2.578 0.462 - 375.6 1 2 0 0.0016 14 0 0 0 1.23E+07 6.52E+06 - - - 6.2071 0.998 221125_WJC_METTL3_EV_vs_WT_F06.14873.14873.3 0.0159 Dec-64 K.MAPVPLDDSNRPASLTK.D "sp|Q9NYF8|BCLF1_HUMAN,tr|E9PKI6|E9PKI6_HUMAN,tr|A0A1W2PQ43|A0A1W2PQ43_HUMAN,tr|E9PK91|E9PK91_HUMAN,tr|E9PJA7|E9PJA7_HUMAN,tr|E9PK09|E9PK09_HUMAN,tr|E9PQN2|E9PQN2_HUMAN" 7 1810.9247 3.28 83938 14873 3 1810.929846 604.6489 Bcl-2-associated transcription factor 1 OS=Homo sapiens OX=9606 GN=BCLAF1 PE=1 SV=2 5.71 2556.2 - 546696 - - - 2.8229 - 2.231 0.28 - 137 1 2 0 0.0051 17 0 0 0 4.59E+06 1.40E+06 - - - 3.6875 0.9999 221125_WJC_METTL3_EV_vs_WT_F06.14877.14877.4 1.86E-06 19/108 R.VLEEYSVPC[160.03]AHAAHVTGLK.L "sp|Q9NNW5|WDR6_HUMAN,tr|E9PBK6|E9PBK6_HUMAN,tr|E9PDU5|E9PDU5_HUMAN,tr|Q6PKC6|Q6PKC6_HUMAN,tr|A0A087X295|A0A087X295_HUMAN" 5 2080.0412 1.09 83942 14877 4 2080.043436 521.0176 WD repeat-containing protein 6 OS=Homo sapiens OX=9606 GN=WDR6 PE=1 SV=1 6 2556.6 - 1.14E+06 - - - 1.0937 - 3.151 0.458 - 202.3 1 2 0 0.0023 19 0 0 0 5.51E+06 5.06E+06 - - - 3.6001 0.9999 221125_WJC_METTL3_EV_vs_WT_F06.14878.14878.3 4.17E-07 14/52 R.GPTPFNQNQLHQLR.A "sp|P51532|SMCA4_HUMAN,tr|A0A2R8Y7S2|A0A2R8Y7S2_HUMAN,tr|Q9HBD4|Q9HBD4_HUMAN,tr|A0A2R8YGP5|A0A2R8YGP5_HUMAN,tr|A0A2R8Y4P4|A0A2R8Y4P4_HUMAN" 5 1648.8434 2.27 83943 14878 3 1648.841248 550.6217 Transcription activator BRG1 OS=Homo sapiens OX=9606 GN=SMARCA4 PE=1 SV=2 9.76 2556.7 - 780933 - - - -1.2973 - 2.945 0.361 - 279.9 1 2 0 -0.0021 14 0 0 0 1.03E+07 4.55E+06 - - - 5.4346 0.8529 221125_WJC_METTL3_EV_vs_WT_F06.14880.14880.3 0.0115 13/40 F.GVISNHLILNK.L "sp|P43243|MATR3_HUMAN,tr|D6RE02|D6RE02_HUMAN,tr|B3KM87|B3KM87_HUMAN,tr|A8MXP9|A8MXP9_HUMAN,tr|D6R991|D6R991_HUMAN,tr|D6RBK5|D6RBK5_HUMAN,tr|A0A0R4J2E8|A0A0R4J2E8_HUMAN,tr|D6RIA2|D6RIA2_HUMAN,tr|H0Y8T4|H0Y8T4_HUMAN,tr|D6REM6|D6REM6_HUMAN,tr|D6RBI2|D6RBI2_HUMAN" 11 1206.7085 1.05 83945 14880 3 1206.708198 403.2434 Matrin-3 OS=Homo sapiens OX=9606 GN=MATR3 PE=1 SV=2 8.76 2557 - 433905 - - - -0.2146 - 2.15 0.202 - 129.4 1 1 0 -0.0003 11 0 0 0 4.76E+06 4.55E+06 - - - 2.9666 1 221125_WJC_METTL3_EV_vs_WT_F06.14884.14884.3 2.84E-07 14/60 R.LQGDANNLHGFEVDSR.V "sp|P52434|RPAB3_HUMAN,tr|C9JLU1|C9JLU1_HUMAN" 2 1770.8285 0.65 83947 14884 3 1770.826765 591.2835 "DNA-directed RNA polymerases I, II, and III subunit RPABC3 OS=Homo sapiens OX=9606 GN=POLR2H PE=1 SV=4" 4.54 2557.5 - 6.64E+06 - - - -0.9939 - 2.619 0.558 - 188.8 1 2 0 -0.0018 16 0 0 0 1.54E+08 2.36E+08 - - - 7.2311 0.9998 221125_WJC_METTL3_EV_vs_WT_F06.14886.14886.3 0.000165 15/56 R.DISTNKVEQIPYGER.L "sp|P49750|YLPM1_HUMAN,tr|H0YIQ2|H0YIQ2_HUMAN,tr|F8VU51|F8VU51_HUMAN,tr|H0YI23|H0YI23_HUMAN" 4 1747.8741 1.47 83949 14886 3 1747.871588 583.632 YLP motif-containing protein 1 OS=Homo sapiens OX=9606 GN=YLPM1 PE=1 SV=4 4.68 2557.7 - 2.10E+06 - - - -1.4246 - 2.813 0.453 - 202 1 2 1 -0.0025 15 0 0 0 2.31E+07 1.57E+07 - - - 6.2886 1 221125_WJC_METTL3_EV_vs_WT_F06.14887.14887.3 5.70E-10 20/76 R.VVIVDPETNKEMSVQEAYKK.G sp|P15924|DESP_HUMAN 1 2306.1828 999 83950 14887 3 2306.178872 769.7349 Desmoplakin OS=Homo sapiens OX=9606 GN=DSP PE=1 SV=3 4.87 2557.8 - 1.30E+06 - - - -1.7028 - 3.599 0.666 - 371 1 2 1 -0.0039 20 0 0 0 2.78E+07 0.00E+00 - - - 9.0711 0.8701 221125_WJC_METTL3_EV_vs_WT_F06.14889.14889.3 2.41 Sep-52 K.IQIPRPDDPSNQIK.L "sp|Q00341|VIGLN_HUMAN,tr|A0A024R4E5|A0A024R4E5_HUMAN,tr|C9JIZ1|C9JIZ1_HUMAN,tr|H7C0A4|H7C0A4_HUMAN,tr|H0Y394|H0Y394_HUMAN,tr|C9J5E5|C9J5E5_HUMAN" 6 1619.8631 1.37 83952 14889 3 1619.864701 540.9616 Vigilin OS=Homo sapiens OX=9606 GN=HDLBP PE=1 SV=2 5.96 2558 - 3.24E+06 - - - 0.976 - 1.423 0.077 - 106.2 1 2 0 0.0016 14 0 0 0 5.78E+07 4.23E+07 - - - 0.3355 0.9998 221125_WJC_METTL3_EV_vs_WT_F06.14890.14890.3 0.00484 14/52 R.GGNNSFTHEALTLK[136.11].Y sp|P08240|SRPRA_HUMAN 1 1495.7511 1.9 83953 14890 3 1495.752244 499.591 Signal recognition particle receptor subunit alpha OS=Homo sapiens OX=9606 GN=SRPRA PE=1 SV=2 6.75 2558.1 - 923617 - - - 0.7942 - 2.128 0.367 - 194.3 1 2 0 0.0012 14 0 0 0 1.24E+07 6.52E+06 - - - 4.6383 0.992 221125_WJC_METTL3_EV_vs_WT_F06.14894.14894.3 0.0656 Sep-60 K.HIMSEPEEITTMSGQK.L "sp|Q9UKF6|CPSF3_HUMAN,tr|G5E9W3|G5E9W3_HUMAN" 2 1816.8335 0.83 83957 14894 3 1816.837486 606.6185 Cleavage and polyadenylation specificity factor subunit 3 OS=Homo sapiens OX=9606 GN=CPSF3 PE=1 SV=1 4.75 2558.6 - 642119 - - - 2.1747 - 1.681 0.229 - 53.4 1 2 0 0.004 16 0 0 0 1.96E+07 2.35E+07 - - - 2.4247 0.9999 221125_WJC_METTL3_EV_vs_WT_F06.14897.14897.2 0.00233 13/30 R.LQGDANNLHGFEVDSR.V "sp|P52434|RPAB3_HUMAN,tr|C9JLU1|C9JLU1_HUMAN" 2 1770.8285 2.44 83960 14897 2 1770.829257 886.4215 "DNA-directed RNA polymerases I, II, and III subunit RPABC3 OS=Homo sapiens OX=9606 GN=POLR2H PE=1 SV=4" 4.54 2559 - 280784 - - - 0.4134 - 2.28 0.485 - 341.9 1 2 0 0.0007 16 0 0 0 8.17E+06 3.35E+06 - - - 4.6493 1 221125_WJC_METTL3_EV_vs_WT_F06.14904.14904.3 0.000127 16/44 K.NGSLTNHFSFEK[136.11].K "sp|P22102|PUR2_HUMAN,tr|A0A140TA71|A0A140TA71_HUMAN" 2 1387.6612 0.75 83965 14904 3 1387.659266 463.561 Trifunctional purine biosynthetic protein adenosine-3 OS=Homo sapiens OX=9606 GN=GART PE=1 SV=1 6.75 2559.7 - 1.28E+06 - - - -1.3786 - 2.667 0.491 - 245.2 1 2 0 -0.0019 12 0 0 0 9.06E+06 1.21E+07 - - - 6.7327 0.9255 221125_WJC_METTL3_EV_vs_WT_F06.14905.14905.4 0.00107 15/84 L.FIGNLPHEVDK[136.11]SELK[136.11].D "sp|Q13283|G3BP1_HUMAN,tr|A0A7I2V5M7|A0A7I2V5M7_HUMAN,tr|A0A7I2V2X7|A0A7I2V2X7_HUMAN,tr|A0A7P0P2U7|A0A7P0P2U7_HUMAN,tr|A0A7I2YQN9|A0A7I2YQN9_HUMAN,tr|A0A7I2YQH0|A0A7I2YQH0_HUMAN" 6 1740.9381 0.87 83966 14905 4 1740.93428 436.2418 Ras GTPase-activating protein-binding protein 1 OS=Homo sapiens OX=9606 GN=G3BP1 PE=1 SV=1 5.45 2559.9 - 1.21E+06 - - - -2.2143 - 2.508 0.419 - 93.5 1 1 1 -0.0039 15 0 0 0 1.47E+07 1.70E+07 - - - 3.2009 1 221125_WJC_METTL3_EV_vs_WT_F06.14907.14907.3 1.33E-05 17/56 K.KAEAGAGSATEFQFR.G "sp|Q9NQ39|RS10L_HUMAN,sp|P46783|RS10_HUMAN" 2 1568.7583 2.11 83968 14907 3 1568.760364 523.9267 Putative 40S ribosomal protein S10-like OS=Homo sapiens OX=9606 GN=RPS10P5 PE=5 SV=1 6.14 2560.1 - 869357 - - - 1.3029 - 3.077 0.471 - 349.8 1 2 0 0.002 15 0 0 0 1.10E+07 5.24E+06 - - - 6.7234 0.9963 221125_WJC_METTL3_EV_vs_WT_F06.14908.14908.2 0.00818 28-Oct R.STSHK[136.11]PDEIYGMIER[166.11].L sp|Q86U44|MTA70_HUMAN 1 1779.8581 0.001 83969 14908 2 1779.850561 890.9363 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 5.42 2560.3 - 778714 - - - -4.2099 - 1.624 0.431 - 214.2 1 2 0 -0.0075 15 0 0 0 0.00E+00 1.16E+07 - - - 3.4141 0.9999 221125_WJC_METTL3_EV_vs_WT_F06.14913.14913.3 8.90E-06 17/48 K.IDYGEYMDKNNVR.R "sp|Q04837|SSBP_HUMAN,tr|A0A0G2JLD8|A0A0G2JLD8_HUMAN,tr|E7EUY5|E7EUY5_HUMAN" 3 1615.7301 1.49 83972 14913 3 1615.726168 539.584 "Single-stranded DNA-binding protein, mitochondrial OS=Homo sapiens OX=9606 GN=SSBP1 PE=1 SV=1" 4.56 2560.7 - 2.81E+06 - - - -2.4063 - 2.988 0.572 - 394.2 1 2 1 -0.0039 13 0 0 0 5.59E+07 3.76E+07 - - - 7.8839 1 221125_WJC_METTL3_EV_vs_WT_F06.14917.14917.3 1.94E-08 17/52 R.GHLLYVALSPGQHR[166.11].L sp|O15067|PUR4_HUMAN 1 1556.8451 0.21 83976 14917 3 1556.845056 519.9556 Phosphoribosylformylglycinamidine synthase OS=Homo sapiens OX=9606 GN=PFAS PE=1 SV=4 8.76 2561.1 - 1.35E+06 - - - -0.0379 - 3.486 0.626 - 561.5 1 2 0 -0.0001 14 0 0 0 3.96E+06 1.87E+07 - - - 8.8379 1 221125_WJC_METTL3_EV_vs_WT_F06.14918.14918.2 3.74E-11 17/34 R.EAGVEMGDEDDLSTPNEK.L "sp|P14868|SYDC_HUMAN,tr|H7BZ35|H7BZ35_HUMAN" 2 1934.8051 2.27 83977 14918 2 1934.806362 968.4098 "Aspartate--tRNA ligase, cytoplasmic OS=Homo sapiens OX=9606 GN=DARS1 PE=1 SV=2" 3.66 2561.2 - 779120 - - - 0.6357 - 3.184 0.758 - 665.9 1 2 0 0.0012 18 0 0 0 1.16E+07 5.11E+06 - - - 7.4865 1 221125_WJC_METTL3_EV_vs_WT_F06.14922.14922.2 9.72E-10 15/22 R.FLEQQNQVLQTK.W "sp|Q7Z794|K2C1B_HUMAN,sp|P04264|K2C1_HUMAN,sp|P35908|K22E_HUMAN" 3 1474.778 999 83979 14922 2 1474.77618 738.3963 "Keratin, type II cytoskeletal 1b OS=Homo sapiens OX=9606 GN=KRT77 PE=1 SV=3" 6 2561.8 - 6.21E+06 - - - -1.2293 - 2.894 0.593 - 729.1 1 2 0 -0.0018 12 0 0 0 3.97E+08 0.00E+00 - - - 6.2163 0.999 221125_WJC_METTL3_EV_vs_WT_F06.14925.14925.3 2.81E-06 21/68 S.FSNTPNSGYTQSQFSAPR.D "sp|Q14444|CAPR1_HUMAN,tr|G3V153|G3V153_HUMAN" 2 1987.9024 1.62 83982 14925 3 1987.903856 663.6414 Caprin-1 OS=Homo sapiens OX=9606 GN=CAPRIN1 PE=1 SV=2 8.75 2562 - 2.25E+06 - - - 0.7234 - 3.474 0.601 - 625.7 1 1 0 0.0014 18 0 0 0 3.38E+07 2.09E+07 - - - 8.3411 1 221125_WJC_METTL3_EV_vs_WT_F06.14933.14933.2 5.16E-12 18/34 S.FSNTPNSGYTQSQFSAPR.D "sp|Q14444|CAPR1_HUMAN,tr|G3V153|G3V153_HUMAN" 2 1987.9024 0.82 83987 14933 2 1987.896587 994.9585 Caprin-1 OS=Homo sapiens OX=9606 GN=CAPRIN1 PE=1 SV=2 8.75 2563 - 1.54E+06 - - - -2.9332 - 3.636 0.724 - 787.9 1 1 0 -0.0058 18 0 0 0 1.63E+07 1.98E+07 - - - 7.5603 1 221125_WJC_METTL3_EV_vs_WT_F06.14934.14934.2 5.07E-11 18/34 S.FSNTPNSGYTQSQFSAPR[166.11].D "sp|Q14444|CAPR1_HUMAN,tr|G3V153|G3V153_HUMAN" 2 1997.9107 0.82 83988 14934 2 1997.90664 999.9626 Caprin-1 OS=Homo sapiens OX=9606 GN=CAPRIN1 PE=1 SV=2 8.75 2563.1 - 1.25E+06 - - - -2.0261 - 3.361 0.697 - 792.1 1 1 0 -0.004 18 0 0 0 1.63E+07 1.98E+07 - - - 7.1681 0.9998 221125_WJC_METTL3_EV_vs_WT_F06.14935.14935.3 0.0695 Nov-32 R.EFADFEYRK.T "sp|Q8ND56|LS14A_HUMAN,tr|A0A140TA66|A0A140TA66_HUMAN" 2 1203.556 1.1 83989 14935 3 1203.555987 402.1926 Protein LSM14 homolog A OS=Homo sapiens OX=9606 GN=LSM14A PE=1 SV=3 4.68 2563.2 - 988798 - - - -0.0424 - 2.005 0.35 - 156.4 1 2 0 -0.0001 9 0 0 0 1.63E+07 1.48E+07 - - - 4.5387 1 221125_WJC_METTL3_EV_vs_WT_F06.14945.14945.3 1.69E-06 17/56 R.STSHK[136.11]PDEIYGMIER[166.11].L sp|Q86U44|MTA70_HUMAN 1 1779.8581 0.001 83994 14945 3 1779.85607 594.2933 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 5.42 2564.5 - 5.55E+06 - - - -1.1147 - 2.897 0.512 - 354.3 1 2 0 -0.002 15 0 0 0 0.00E+00 1.63E+08 - - - 7.0233 1 221125_WJC_METTL3_EV_vs_WT_F06.14946.14946.2 4.60E-13 17/28 K.NGDTSTEEPMLNVQR.L "sp|P82930|RT34_HUMAN,tr|C9JJ19|C9JJ19_HUMAN" 2 1689.7628 1.69 83995 14946 2 1689.761488 845.8887 "28S ribosomal protein S34, mitochondrial OS=Homo sapiens OX=9606 GN=MRPS34 PE=1 SV=2" 4.14 2564.6 - 3.63E+06 - - - -0.7841 - 3.258 0.701 - 830.2 1 2 0 -0.0013 15 0 0 0 9.10E+07 5.39E+07 - - - 7.122 1 221125_WJC_METTL3_EV_vs_WT_F06.14950.14950.3 1.06E-07 17/60 K.MWDPHNDPNAQGDAFK[136.11].T "sp|P08621|RU17_HUMAN,tr|M0QYR1|M0QYR1_HUMAN" 2 1849.7933 1.5 83999 14950 3 1849.788336 617.6051 U1 small nuclear ribonucleoprotein 70 kDa OS=Homo sapiens OX=9606 GN=SNRNP70 PE=1 SV=2 4.41 2565 - 2.12E+06 - - - -2.7008 - 3.04 0.629 - 374.9 1 2 0 -0.005 16 0 0 0 9.50E+07 6.33E+07 - - - 8.4042 1 221125_WJC_METTL3_EV_vs_WT_F06.14958.14958.3 9.86E-08 16/60 K.MWDPHNDPNAQGDAFK.T "sp|P08621|RU17_HUMAN,tr|M0QYR1|M0QYR1_HUMAN" 2 1841.7791 1.5 84003 14958 3 1841.780421 614.9337 U1 small nuclear ribonucleoprotein 70 kDa OS=Homo sapiens OX=9606 GN=SNRNP70 PE=1 SV=2 4.41 2565.9 - 3.59E+06 - - - 0.6999 - 2.823 0.579 - 398.6 1 2 0 0.0013 16 0 0 0 9.50E+07 6.33E+07 - - - 7.6578 0.7684 221125_WJC_METTL3_EV_vs_WT_F06.14960.14960.3 0.63 Jul-48 R.TETTHYPENFDLK.G "sp|O95985|TOP3B_HUMAN,tr|H7C4B0|H7C4B0_HUMAN,tr|H0Y6W0|H0Y6W0_HUMAN" 3 1593.7311 1.81 84005 14960 3 1593.721867 532.251 DNA topoisomerase 3-beta-1 OS=Homo sapiens OX=9606 GN=TOP3B PE=1 SV=1 4.65 2566.1 - 2.31E+06 - - - -5.7946 - 1.313 0.224 - 49.5 1 2 0 -0.0092 13 0 0 0 5.72E+07 3.17E+07 - - - 1.7731 1 221125_WJC_METTL3_EV_vs_WT_F06.14963.14963.2 4.60E-11 16/28 K.NGDTSTEEPMLNVQR[166.11].L "sp|P82930|RT34_HUMAN,tr|C9JJ19|C9JJ19_HUMAN" 2 1699.7711 1.69 84006 14963 2 1699.760757 850.8928 "28S ribosomal protein S34, mitochondrial OS=Homo sapiens OX=9606 GN=MRPS34 PE=1 SV=2" 4.14 2566.5 - 2.47E+06 - - - -6.0749 - 3.471 0.67 - 712 1 2 0 -0.0103 15 0 0 0 9.10E+07 5.39E+07 - - - 7.0459 1 221125_WJC_METTL3_EV_vs_WT_F06.14970.14970.4 3.09E-06 18/90 K.FQEHIIQAPK[136.11]PVEAIK[136.11].R "sp|Q9UHD1|CHRD1_HUMAN,tr|E9PSD5|E9PSD5_HUMAN,tr|E9PIZ4|E9PIZ4_HUMAN,tr|E9PPQ5|E9PPQ5_HUMAN" 4 1863.0589 0.36 84012 14970 4 1863.055255 466.772 Cysteine and histidine-rich domain-containing protein 1 OS=Homo sapiens OX=9606 GN=CHORDC1 PE=1 SV=2 6.76 2567.1 - 2.40E+06 - - - -1.9667 - 3.036 0.52 - 153.8 1 2 0 -0.0037 16 0 0 0 1.68E+07 4.66E+07 - - - 4.1423 0.9998 221125_WJC_METTL3_EV_vs_WT_F06.14972.14972.3 0.00229 Dec-44 R.FLEQQNQVLQTK.W "sp|Q7Z794|K2C1B_HUMAN,sp|P04264|K2C1_HUMAN,sp|P35908|K22E_HUMAN" 3 1474.778 999 84014 14972 3 1474.777956 492.5999 "Keratin, type II cytoskeletal 1b OS=Homo sapiens OX=9606 GN=KRT77 PE=1 SV=3" 6 2567.3 - 1.68E+06 - - - -0.0251 - 2.067 0.349 - 174.5 1 2 0 0 12 0 0 0 2.84E+07 0.00E+00 - - - 4.4436 0.9908 221125_WJC_METTL3_EV_vs_WT_F06.14982.14982.2 0.243 16-Aug K.EIAEAYLGK[136.11].T "sp|P11142|HSP7C_HUMAN,tr|E9PQQ4|E9PQQ4_HUMAN,tr|E9PKE3|E9PKE3_HUMAN,tr|E9PN89|E9PN89_HUMAN,tr|E9PLF4|E9PLF4_HUMAN,tr|E9PI65|E9PI65_HUMAN,tr|E9PK54|E9PK54_HUMAN,tr|E9PPY6|E9PPY6_HUMAN,tr|E9PQK7|E9PQK7_HUMAN" 9 1000.5321 0.23 84020 14982 2 1000.52935 501.2733 Heat shock cognate 71 kDa protein OS=Homo sapiens OX=9606 GN=HSPA8 PE=1 SV=1 4.53 2568.5 - 0 - - - -2.7106 - 1.555 0.174 - 160.6 1 2 0 -0.0027 9 0 0 0 1.06E+06 4.54E+06 - - - 1.6025 0.9975 221125_WJC_METTL3_EV_vs_WT_F06.14983.14983.2 8.87E-05 15/26 K.NTNAAEESLPEIQK.E "sp|Q9NTJ3|SMC4_HUMAN,tr|E9PD53|E9PD53_HUMAN" 2 1542.7526 2.16 84021 14983 2 1542.760062 772.3836 Structural maintenance of chromosomes protein 4 OS=Homo sapiens OX=9606 GN=SMC4 PE=1 SV=2 4.25 2568.7 - 1.55E+06 - - - 4.8588 - 2.788 0.403 - 513.1 1 2 0 0.0075 14 0 0 0 4.23E+07 1.96E+07 - - - 4.5882 0.9998 221125_WJC_METTL3_EV_vs_WT_F06.14986.14986.3 0.00249 Dec-56 K.LK[136.11]PNLGNGADLPNYR[166.11].W "sp|Q9Y266|NUDC_HUMAN,tr|A0A0A0MSS4|A0A0A0MSS4_HUMAN,tr|A0A0A0MSU9|A0A0A0MSU9_HUMAN" 3 1658.8859 1.63 84022 14986 3 1658.885566 553.9693 Nuclear migration protein nudC OS=Homo sapiens OX=9606 GN=NUDC PE=1 SV=1 8.59 2569.1 - 3.54E+06 - - - -0.2158 - 2.279 0.359 - 149.7 1 2 0 -0.0004 15 0 0 0 7.88E+07 4.84E+07 - - - 4.6918 0.7766 221125_WJC_METTL3_EV_vs_WT_F06.14988.14988.3 0.17 13/56 L.PPPPALEDLPLPPPK.E sp|Q702N8|XIRP1_HUMAN 1 1576.8865 999 84024 14988 3 1576.88126 526.6361 Xin actin-binding repeat-containing protein 1 OS=Homo sapiens OX=9606 GN=XIRP1 PE=1 SV=1 4.37 2569.3 - 1.28E+06 - - - -3.311 - 2.129 0.287 - 193.5 1 1 0 -0.0052 15 0 0 0 2.39E+07 0.00E+00 - - - 3.7101 1 221125_WJC_METTL3_EV_vs_WT_F06.14990.14990.3 1.26E-06 14/52 K.R[166.11]TTAATLMNAYSSR[166.11].S "sp|P52732|KIF11_HUMAN,tr|A0A7I2YQY4|A0A7I2YQY4_HUMAN,tr|A0A7I2V3A9|A0A7I2V3A9_HUMAN,tr|A0A7I2V3V3|A0A7I2V3V3_HUMAN" 4 1561.7786 5.13 84026 14990 3 1561.77672 521.6001 Kinesin-like protein KIF11 OS=Homo sapiens OX=9606 GN=KIF11 PE=1 SV=2 10.84 2569.6 - 1.09E+06 - - - -1.1813 - 2.916 0.545 - 390.7 1 2 0 -0.0018 14 0 0 0 5.99E+07 1.17E+07 - - - 7.4598 0.9999 221125_WJC_METTL3_EV_vs_WT_F06.14996.14996.3 4.28E-05 13/44 R.SNAYHFPDEPYK[136.11].D "sp|Q9NUQ7|UFSP2_HUMAN,tr|D6RGX2|D6RGX2_HUMAN,tr|H0YA18|H0YA18_HUMAN" 3 1474.6608 1.1 84030 14996 3 1474.658203 492.5609 Ufm1-specific protease 2 OS=Homo sapiens OX=9606 GN=UFSP2 PE=1 SV=3 5.3 2570.3 - 1.34E+06 - - - -1.7909 - 2.266 0.481 - 221.7 1 2 0 -0.0026 12 0 0 0 2.10E+07 1.91E+07 - - - 6.1694 1 221125_WJC_METTL3_EV_vs_WT_F06.14997.14997.3 1.57E-10 24/60 K.FQEHIIQAPK[136.11]PVEAIK[136.11].R "sp|Q9UHD1|CHRD1_HUMAN,tr|E9PSD5|E9PSD5_HUMAN,tr|E9PIZ4|E9PIZ4_HUMAN,tr|E9PPQ5|E9PPQ5_HUMAN" 4 1863.0589 0.31 84031 14997 3 1863.059507 622.0269 Cysteine and histidine-rich domain-containing protein 1 OS=Homo sapiens OX=9606 GN=CHORDC1 PE=1 SV=2 6.76 2570.4 - 1.88E+06 - - - 0.3156 - 3.872 0.615 - 637.6 1 2 0 0.0006 16 0 0 0 1.03E+07 3.35E+07 - - - 8.8701 1 221125_WJC_METTL3_EV_vs_WT_F06.14999.14999.4 1.74E-07 20/90 K.FQEHIIQAPKPVEAIK.R "sp|Q9UHD1|CHRD1_HUMAN,tr|E9PSD5|E9PSD5_HUMAN,tr|E9PIZ4|E9PIZ4_HUMAN,tr|E9PPQ5|E9PPQ5_HUMAN" 4 1847.0305 0.36 84033 14999 4 1847.02858 462.7649 Cysteine and histidine-rich domain-containing protein 1 OS=Homo sapiens OX=9606 GN=CHORDC1 PE=1 SV=2 6.76 2570.6 - 1.35E+06 - - - -1.0498 - 3.193 0.464 - 246.6 1 2 0 -0.0019 16 0 0 0 1.68E+07 4.66E+07 - - - 3.6731 1 221125_WJC_METTL3_EV_vs_WT_F06.15000.15000.3 3.92E-05 15/44 R.SNAYHFPDEPYK.D "sp|Q9NUQ7|UFSP2_HUMAN,tr|D6RGX2|D6RGX2_HUMAN,tr|H0YA18|H0YA18_HUMAN" 3 1466.6466 1.1 84034 15000 3 1466.644515 489.8895 Ufm1-specific protease 2 OS=Homo sapiens OX=9606 GN=UFSP2 PE=1 SV=3 5.3 2570.8 - 1.06E+06 - - - -1.4516 - 2.735 0.487 - 315.8 1 2 0 -0.0021 12 0 0 0 2.10E+07 1.91E+07 - - - 6.7578 0.9998 221125_WJC_METTL3_EV_vs_WT_F06.15002.15002.3 0.000725 Dec-52 R.KIEVSLQPEVPPSK.Q "sp|Q9H8H0|NOL11_HUMAN,tr|J3QR28|J3QR28_HUMAN" 2 1549.8716 0.91 84036 15002 3 1549.869585 517.6311 Nucleolar protein 11 OS=Homo sapiens OX=9606 GN=NOL11 PE=1 SV=1 6.14 2571 - 753870 - - - -1.2737 - 2.507 0.337 - 185.1 1 2 0 -0.002 14 0 0 0 5.46E+06 6.01E+06 - - - 4.7392 1 221125_WJC_METTL3_EV_vs_WT_F06.15003.15003.2 5.49E-08 15/32 R.SVSSNVASVSPIPAGSK.K "sp|Q9Y6G9|DC1L1_HUMAN,tr|E9PHI6|E9PHI6_HUMAN" 2 1585.8312 0.83 84037 15003 2 1585.8253 793.9229 Cytoplasmic dynein 1 light intermediate chain 1 OS=Homo sapiens OX=9606 GN=DYNC1LI1 PE=1 SV=3 8.47 2571.2 - 477975 - - - -3.6895 - 2.962 0.6 - 436.3 1 2 0 -0.0059 17 0 0 0 8.36E+06 1.01E+07 - - - 6.1404 0.9995 221125_WJC_METTL3_EV_vs_WT_F06.15006.15006.3 0.00292 Aug-56 K.LKPNLGNGADLPNYR.W "sp|Q9Y266|NUDC_HUMAN,tr|A0A0A0MSS4|A0A0A0MSS4_HUMAN,tr|A0A0A0MSU9|A0A0A0MSU9_HUMAN" 3 1640.8635 1.61 84038 15006 3 1640.86143 547.9618 Nuclear migration protein nudC OS=Homo sapiens OX=9606 GN=NUDC PE=1 SV=1 8.59 2571.6 - 7.99E+06 - - - -1.2335 - 1.845 0.337 - 60.5 1 2 0 -0.002 15 0 0 0 7.78E+07 4.84E+07 - - - 3.8948 0.9999 221125_WJC_METTL3_EV_vs_WT_F06.15007.15007.3 5.53E-09 16/56 K.DKYVGVSSDSVGGFR.Y sp|Q14677|EPN4_HUMAN 1 1571.758 1.39 84039 15007 3 1571.755338 524.9266 Clathrin interactor 1 OS=Homo sapiens OX=9606 GN=CLINT1 PE=1 SV=1 5.96 2571.6 - 3.71E+06 - - - -1.6847 - 3.325 0.567 - 302.9 1 2 1 -0.0026 15 0 0 0 4.38E+08 3.15E+08 - - - 7.9958 1 221125_WJC_METTL3_EV_vs_WT_F06.15008.15008.2 1.08E-10 16/28 R.AQVQEFC[160.03]DYGTK[136.11]EEC[160.03].M "sp|Q86U44|MTA70_HUMAN,tr|H0YFV6|H0YFV6_HUMAN" 2 1870.7593 0.01 84040 15008 2 1870.751262 936.3869 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 4 2571.7 - 1.90E+06 - - - -4.3047 - 3.168 0.719 - 616.3 1 1 1 -0.0081 15 0 0 0 8.48E+05 6.37E+07 - - - 7.184 0.9997 221125_WJC_METTL3_EV_vs_WT_F06.15009.15009.3 0.00115 Nov-40 R.ERPAAISIEIK.S sp|Q15208|STK38_HUMAN 1 1225.703 5.05 84041 15009 3 1225.700398 409.575 Serine\threonine-protein kinase 38 OS=Homo sapiens OX=9606 GN=STK38 PE=1 SV=1 6.24 2571.8 - 1.43E+06 - - - -2.1531 - 2.114 0.374 - 141.9 1 2 0 -0.0026 11 0 0 0 1.65E+07 3.28E+06 - - - 4.8356 1 221125_WJC_METTL3_EV_vs_WT_F06.15010.15010.2 8.68E-10 16/32 R.FSDQAGPAIPTSNSYSK[136.11].K "tr|A0A0A0MRU9|A0A0A0MRU9_HUMAN,tr|E7ETY4|E7ETY4_HUMAN,tr|A0A7I2YQR3|A0A7I2YQR3_HUMAN,tr|E9PC69|E9PC69_HUMAN,tr|A0A7I2V3R3|A0A7I2V3R3_HUMAN" 5 1776.841 0.81 84042 15010 2 1776.835914 889.4278 Non-specific serine\threonine protein kinase OS=Homo sapiens OX=9606 GN=MARK2 PE=1 SV=1 5.83 2572 - 1.23E+06 - - - -2.859 - 3.425 0.653 - 442.6 1 2 0 -0.0051 17 0 0 0 1.49E+07 1.83E+07 - - - 6.8892 1 221125_WJC_METTL3_EV_vs_WT_F06.15013.15013.2 4.05E-09 15/32 R.FSDQAGPAIPTSNSYSK.K "tr|A0A0A0MRU9|A0A0A0MRU9_HUMAN,tr|E7ETY4|E7ETY4_HUMAN,tr|A0A7I2YQR3|A0A7I2YQR3_HUMAN,tr|E9PC69|E9PC69_HUMAN,tr|A0A7I2V3R3|A0A7I2V3R3_HUMAN" 5 1768.8268 0.58 84045 15013 2 1768.828374 885.4207 Non-specific serine\threonine protein kinase OS=Homo sapiens OX=9606 GN=MARK2 PE=1 SV=1 5.83 2572.4 - 949668 - - - 0.8932 - 3.291 0.629 - 375.1 1 2 0 0.0016 17 0 0 0 1.06E+07 1.83E+07 - - - 6.6149 0.9991 221125_WJC_METTL3_EV_vs_WT_F06.15014.15014.2 0.000159 13/22 K.QQIQSIQQSIER.L "sp|P55769|NH2L1_HUMAN,tr|B1AHD1|B1AHD1_HUMAN,tr|A0A3B3IUA2|A0A3B3IUA2_HUMAN,tr|A0A3B3IRU2|A0A3B3IRU2_HUMAN" 4 1456.7634 1.74 84046 15014 2 1456.757669 729.389 NHP2-like protein 1 OS=Homo sapiens OX=9606 GN=SNU13 PE=1 SV=3 6 2572.5 - 922717 - - - -3.9375 - 2.667 0.491 - 865.6 1 2 0 -0.0057 12 0 0 0 9.89E+07 5.68E+07 - - - 5.2468 0.9997 221125_WJC_METTL3_EV_vs_WT_F06.15021.15021.3 0.0548 15/44 R.C[160.03]KELGITALHIK.L "sp|P62263|RS14_HUMAN,tr|A0A2R8Y811|A0A2R8Y811_HUMAN,tr|E5RH77|E5RH77_HUMAN" 3 1381.7752 1.13 84051 15021 3 1381.774171 461.599 40S ribosomal protein S14 OS=Homo sapiens OX=9606 GN=RPS14 PE=1 SV=3 8.21 2573.3 - 5.11E+06 - - - -0.7129 - 2.409 0.419 - 470.8 1 2 1 -0.001 12 0 0 0 3.97E+07 3.50E+07 - - - 5.6482 1 221125_WJC_METTL3_EV_vs_WT_F06.15022.15022.3 4.03E-10 21/76 R.LAEDAPNFDGPAAEGQPGQK.Q "sp|P78344|IF4G2_HUMAN,tr|H0YEC5|H0YEC5_HUMAN,tr|H0Y3P2|H0Y3P2_HUMAN,tr|H0YCH5|H0YCH5_HUMAN,tr|H0YD77|H0YD77_HUMAN,tr|D3DQV9|D3DQV9_HUMAN" 6 2010.9283 2.7 84052 15022 3 2010.927738 671.3167 Eukaryotic translation initiation factor 4 gamma 2 OS=Homo sapiens OX=9606 GN=EIF4G2 PE=1 SV=1 3.92 2573.4 - 2.51E+06 - - - -0.279 - 3.306 0.623 - 360.1 1 2 0 -0.0006 20 0 0 0 1.09E+08 4.03E+07 - - - 8.3866 0.9999 221125_WJC_METTL3_EV_vs_WT_F06.15025.15025.2 9.07E-05 13/22 K.QQIQSIQQSIER[166.11].L "sp|P55769|NH2L1_HUMAN,tr|B1AHD1|B1AHD1_HUMAN,tr|A0A3B3IUA2|A0A3B3IUA2_HUMAN,tr|A0A3B3IRU2|A0A3B3IRU2_HUMAN" 4 1466.7717 1.74 84055 15025 2 1466.771657 734.3931 NHP2-like protein 1 OS=Homo sapiens OX=9606 GN=SNU13 PE=1 SV=3 6 2573.6 - 2.05E+06 - - - -0.0123 - 2.817 0.466 - 881 1 2 0 0 12 0 0 0 9.89E+07 5.68E+07 - - - 5.2079 1 221125_WJC_METTL3_EV_vs_WT_F06.15026.15026.3 2.85E-08 15/68 K.LPTEVNHVPSGPSIPADR.T sp|Q96T58|MINT_HUMAN 1 1884.9694 1.28 84056 15026 3 1884.967084 629.3304 Msx2-interacting protein OS=Homo sapiens OX=9606 GN=SPEN PE=1 SV=1 5.32 2573.6 - 1.68E+06 - - - -1.2159 - 3.213 0.501 - 191.6 1 2 0 -0.0023 18 0 0 0 3.76E+07 2.93E+07 - - - 7.0315 0.9989 221125_WJC_METTL3_EV_vs_WT_F06.15029.15029.2 4.71E-08 28-Nov K.DKYVGVSSDSVGGFR.Y sp|Q14677|EPN4_HUMAN 1 1571.758 1.59 84059 15029 2 1571.757835 786.8863 Clathrin interactor 1 OS=Homo sapiens OX=9606 GN=CLINT1 PE=1 SV=1 5.96 2574 - 859185 - - - -0.0961 - 2.39 0.562 - 264.3 1 2 1 -0.0002 15 0 0 0 3.56E+07 2.24E+07 - - - 5.334 1 221125_WJC_METTL3_EV_vs_WT_F06.15030.15030.2 1.79E-12 21/38 R.LAEDAPNFDGPAAEGQPGQK.Q "sp|P78344|IF4G2_HUMAN,tr|H0YEC5|H0YEC5_HUMAN,tr|H0Y3P2|H0Y3P2_HUMAN,tr|H0YCH5|H0YCH5_HUMAN,tr|H0YD77|H0YD77_HUMAN,tr|D3DQV9|D3DQV9_HUMAN" 6 2010.9283 2.87 84060 15030 2 2010.929052 1006.4714 Eukaryotic translation initiation factor 4 gamma 2 OS=Homo sapiens OX=9606 GN=EIF4G2 PE=1 SV=1 3.92 2574.2 - 836595 - - - 0.3745 - 3.649 0.681 - 921.3 1 2 0 0.0008 20 0 0 0 4.50E+07 1.57E+07 - - - 7.2531 0.9995 221125_WJC_METTL3_EV_vs_WT_F06.15032.15032.3 0.0369 13/44 K.QQIQSIQQSIER.L "sp|P55769|NH2L1_HUMAN,tr|B1AHD1|B1AHD1_HUMAN,tr|A0A3B3IUA2|A0A3B3IUA2_HUMAN,tr|A0A3B3IRU2|A0A3B3IRU2_HUMAN" 4 1456.7634 1.01 84062 15032 3 1456.764095 486.5951 NHP2-like protein 1 OS=Homo sapiens OX=9606 GN=SNU13 PE=1 SV=3 6 2574.4 - 742098 - - - 0.4737 - 2.059 0.298 - 261.4 1 2 0 0.0007 12 0 0 0 2.80E+07 2.77E+07 - - - 3.8641 1 221125_WJC_METTL3_EV_vs_WT_F06.15035.15035.2 9.40E-07 17/28 K.DK[136.11]YVGVSSDSVGGFR[166.11].Y sp|Q14677|EPN4_HUMAN 1 1589.7805 1.59 84065 15035 2 1589.779009 795.8975 Clathrin interactor 1 OS=Homo sapiens OX=9606 GN=CLINT1 PE=1 SV=1 5.96 2574.8 - 666927 - - - -0.9102 - 2.858 0.587 - 926 1 2 1 -0.0014 15 0 0 0 3.56E+07 2.24E+07 - - - 5.9579 0.9982 221125_WJC_METTL3_EV_vs_WT_F06.15037.15037.2 2.01E-07 24-Dec R.NEQDAYAINSYTR[166.11].S "sp|P24752|THIL_HUMAN,tr|A0A5F9ZHJ7|A0A5F9ZHJ7_HUMAN,tr|A0A5F9ZHD4|A0A5F9ZHD4_HUMAN,tr|A0A5F9ZHJ0|A0A5F9ZHJ0_HUMAN,tr|A0A5F9ZHL1|A0A5F9ZHL1_HUMAN,tr|A0A5F9ZI66|A0A5F9ZI66_HUMAN" 6 1553.6986 0.6 84067 15037 2 1553.690941 777.8566 "Acetyl-CoA acetyltransferase, mitochondrial OS=Homo sapiens OX=9606 GN=ACAT1 PE=1 SV=1" 4.37 2575 - 500150 - - - -4.9102 - 2.259 0.549 - 497 1 2 0 -0.0076 13 0 0 0 2.06E+06 3.42E+06 - - - 5.185 1 221125_WJC_METTL3_EV_vs_WT_F06.15039.15039.4 1.23E-06 14/72 K.FAWGHDELK[136.11]PVSR[166.11].S "sp|Q9UKM7|MA1B1_HUMAN,tr|A0A804HK28|A0A804HK28_HUMAN,tr|H0YG20|H0YG20_HUMAN,tr|A0A804HKS1|A0A804HKS1_HUMAN,tr|H0YGV7|H0YGV7_HUMAN,tr|A0A804HL65|A0A804HL65_HUMAN,tr|A0A804HIP1|A0A804HIP1_HUMAN,tr|A0A804HK01|A0A804HK01_HUMAN,tr|A0A804HJ23|A0A804HJ23_HUMAN,tr|A0A804HHU1|A0A804HHU1_HUMAN,tr|A0A804HK86|A0A804HK86_HUMAN,tr|A0A804HL61|A0A804HL61_HUMAN,tr|A0A804HJ66|A0A804HJ66_HUMAN,tr|H0YGQ1|H0YGQ1_HUMAN,tr|A0A804HJW0|A0A804HJW0_HUMAN" 15 1558.8011 1.62 84069 15039 4 1558.798701 390.7076 "Endoplasmic reticulum mannosyl-oligosaccharide 1,2-alpha-mannosidase OS=Homo sapiens OX=9606 GN=MAN1B1 PE=1 SV=2" 6.75 2575.3 - 458984 - - - -1.5595 - 2.608 0.549 - 93.4 1 2 0 -0.0024 13 0 0 0 8.24E+06 5.07E+06 - - - 4.3592 1 221125_WJC_METTL3_EV_vs_WT_F06.15040.15040.4 3.65E-05 17/72 K.FAWGHDELKPVSR.S "sp|Q9UKM7|MA1B1_HUMAN,tr|A0A804HK28|A0A804HK28_HUMAN,tr|H0YG20|H0YG20_HUMAN,tr|A0A804HKS1|A0A804HKS1_HUMAN,tr|H0YGV7|H0YGV7_HUMAN,tr|A0A804HL65|A0A804HL65_HUMAN,tr|A0A804HIP1|A0A804HIP1_HUMAN,tr|A0A804HK01|A0A804HK01_HUMAN,tr|A0A804HJ23|A0A804HJ23_HUMAN,tr|A0A804HHU1|A0A804HHU1_HUMAN,tr|A0A804HK86|A0A804HK86_HUMAN,tr|A0A804HL61|A0A804HL61_HUMAN,tr|A0A804HJ66|A0A804HJ66_HUMAN,tr|H0YGQ1|H0YGQ1_HUMAN,tr|A0A804HJW0|A0A804HJW0_HUMAN" 15 1540.7787 1.62 84070 15040 4 1540.775337 386.2019 "Endoplasmic reticulum mannosyl-oligosaccharide 1,2-alpha-mannosidase OS=Homo sapiens OX=9606 GN=MAN1B1 PE=1 SV=2" 6.75 2575.4 - 456693 - - - -2.158 - 2.903 0.518 - 167.1 1 2 0 -0.0033 13 0 0 0 8.24E+06 5.07E+06 - - - 4.1289 0.9975 221125_WJC_METTL3_EV_vs_WT_F06.15042.15042.3 0.0721 Nov-52 R.TYSLGSALRPSTSR.S "sp|P08670|VIME_HUMAN,tr|B0YJC4|B0YJC4_HUMAN,tr|A0A1B0GVG8|A0A1B0GVG8_HUMAN,tr|A0A1B0GTT5|A0A1B0GTT5_HUMAN" 4 1494.7791 0.32 84071 15042 3 1494.779298 499.267 Vimentin OS=Homo sapiens OX=9606 GN=VIM PE=1 SV=4 10.83 2575.8 - 390316 - - - 0.1619 - 1.629 0.255 - 126.3 1 2 0 0.0002 14 0 0 0 8.13E+06 2.51E+07 - - - 2.6797 1 221125_WJC_METTL3_EV_vs_WT_F06.15045.15045.3 2.11E-06 16/76 R.LAEDAPNFDGPAAEGQPGQK[136.11].Q "sp|P78344|IF4G2_HUMAN,tr|H0YEC5|H0YEC5_HUMAN,tr|H0Y3P2|H0Y3P2_HUMAN,tr|H0YCH5|H0YCH5_HUMAN,tr|H0YD77|H0YD77_HUMAN,tr|D3DQV9|D3DQV9_HUMAN" 6 2018.9425 2.68 84074 15045 3 2018.940674 673.9881 Eukaryotic translation initiation factor 4 gamma 2 OS=Homo sapiens OX=9606 GN=EIF4G2 PE=1 SV=1 3.92 2576 - 2.48E+06 - - - -0.9039 - 2.925 0.555 - 189.1 1 2 0 -0.0018 20 0 0 0 1.08E+08 4.03E+07 - - - 7.331 0.9997 221125_WJC_METTL3_EV_vs_WT_F06.15046.15046.3 0.00115 13/44 K.QQIQSIQQSIER[166.11].L "sp|P55769|NH2L1_HUMAN,tr|B1AHD1|B1AHD1_HUMAN,tr|A0A3B3IUA2|A0A3B3IUA2_HUMAN,tr|A0A3B3IRU2|A0A3B3IRU2_HUMAN" 4 1466.7717 1.61 84075 15046 3 1466.773368 489.9312 NHP2-like protein 1 OS=Homo sapiens OX=9606 GN=SNU13 PE=1 SV=3 6 2576.1 - 1.81E+06 - - - 1.1542 - 2.411 0.293 - 356.6 1 2 0 0.0017 12 0 0 0 2.75E+07 1.72E+07 - - - 4.2455 1 221125_WJC_METTL3_EV_vs_WT_F06.15051.15051.3 2.34E-07 13/60 K.FQEHIIQAPKPVEAIK.R "sp|Q9UHD1|CHRD1_HUMAN,tr|E9PSD5|E9PSD5_HUMAN,tr|E9PIZ4|E9PIZ4_HUMAN,tr|E9PPQ5|E9PPQ5_HUMAN" 4 1847.0305 0.31 84080 15051 3 1847.029434 616.6841 Cysteine and histidine-rich domain-containing protein 1 OS=Homo sapiens OX=9606 GN=CHORDC1 PE=1 SV=2 6.76 2576.6 - 586226 - - - -0.5874 - 2.693 0.508 - 168.4 1 2 0 -0.0011 16 0 0 0 1.03E+07 3.35E+07 - - - 6.7453 0.9997 221125_WJC_METTL3_EV_vs_WT_F06.15055.15055.2 4.11E-06 14/30 R.SSTPLPTISSSAENTR.Q "sp|P42166|LAP2A_HUMAN,sp|P42167|LAP2B_HUMAN,tr|G5E972|G5E972_HUMAN,tr|H0YJH7|H0YJH7_HUMAN" 4 1646.8111 1.19 84084 15055 2 1646.813342 824.4128 "Lamina-associated polypeptide 2, isoform alpha OS=Homo sapiens OX=9606 GN=TMPO PE=1 SV=2" 5.72 2577.1 - 377458 - - - 1.3347 - 2.24 0.444 - 367.3 1 2 0 0.0022 16 0 0 0 9.70E+07 8.14E+07 - - - 4.3025 1 221125_WJC_METTL3_EV_vs_WT_F06.15056.15056.3 2.35E-05 20/72 K.TSPLVLDSNTVTQGHTAGR[166.11].K sp|Q92545|TM131_HUMAN 1 1962.9998 1.32 84085 15056 3 1962.998456 655.3406 Transmembrane protein 131 OS=Homo sapiens OX=9606 GN=TMEM131 PE=1 SV=3 6.41 2577.3 - 369725 - - - -0.704 - 2.895 0.503 - 349.4 1 2 0 -0.0014 19 0 0 0 3.20E+06 2.42E+06 - - - 6.7591 0.9998 221125_WJC_METTL3_EV_vs_WT_F06.15057.15057.2 6.54E-06 30-Dec R.SSTPLPTISSSAENTR[166.11].Q "sp|P42166|LAP2A_HUMAN,sp|P42167|LAP2B_HUMAN,tr|G5E972|G5E972_HUMAN,tr|H0YJH7|H0YJH7_HUMAN" 4 1656.8194 1.15 84086 15057 2 1656.818521 829.417 "Lamina-associated polypeptide 2, isoform alpha OS=Homo sapiens OX=9606 GN=TMPO PE=1 SV=2" 5.72 2577.4 - 365651 - - - -0.539 - 2.117 0.469 - 228.9 1 2 0 -0.0009 16 0 0 0 4.64E+07 4.04E+07 - - - 4.3487 1 221125_WJC_METTL3_EV_vs_WT_F06.15060.15060.3 1.94E-08 17/56 K.DK[136.11]YVGVSSDSVGGFR[166.11].Y sp|Q14677|EPN4_HUMAN 1 1589.7805 1.51 84088 15060 3 1589.780426 530.9341 Clathrin interactor 1 OS=Homo sapiens OX=9606 GN=CLINT1 PE=1 SV=1 5.96 2577.8 - 3.41E+07 - - - -0.0189 - 3.352 0.589 - 326.5 1 2 1 0 15 0 0 0 4.25E+08 2.82E+08 - - - 8.2629 0.9997 221125_WJC_METTL3_EV_vs_WT_F06.15062.15062.3 0.0129 14/44 R.C[160.03]K[136.11]ELGITALHIK[136.11].L "sp|P62263|RS14_HUMAN,tr|A0A2R8Y811|A0A2R8Y811_HUMAN,tr|E5RH77|E5RH77_HUMAN" 3 1397.8036 1.13 84089 15062 3 1397.804329 466.9418 40S ribosomal protein S14 OS=Homo sapiens OX=9606 GN=RPS14 PE=1 SV=3 8.21 2578 - 2.71E+06 - - - 0.553 - 2.534 0.418 - 312.3 1 2 1 0.0008 12 0 0 0 3.97E+07 3.50E+07 - - - 5.7773 0.9942 221125_WJC_METTL3_EV_vs_WT_F06.15063.15063.3 0.000618 Dec-36 T.GHHSSMFWMR.V "sp|O14744|ANM5_HUMAN,tr|C9JSX3|C9JSX3_HUMAN,tr|G3V2X6|G3V2X6_HUMAN,tr|G3V5L5|G3V5L5_HUMAN,tr|H0YJX6|H0YJX6_HUMAN" 5 1274.5437 1.7 84090 15063 3 1274.543336 425.8552 Protein arginine N-methyltransferase 5 OS=Homo sapiens OX=9606 GN=PRMT5 PE=1 SV=4 9.76 2578.1 - 803127 - - - -0.2981 - 1.985 0.471 - 194.6 1 1 0 -0.0004 10 0 0 0 5.41E+06 3.18E+06 - - - 5.7934 1 221125_WJC_METTL3_EV_vs_WT_F06.15070.15070.3 5.09E-06 16/40 R.MVNHFIAEFK[136.11]R[166.11].K "sp|P11142|HSP7C_HUMAN,tr|A8K7Q2|A8K7Q2_HUMAN,tr|E9PKE3|E9PKE3_HUMAN,tr|E9PN89|E9PN89_HUMAN" 4 1408.7404 0.21 84095 15070 3 1408.741464 470.5874 Heat shock cognate 71 kDa protein OS=Homo sapiens OX=9606 GN=HSPA8 PE=1 SV=1 8.52 2579 - 1.64E+06 - - - 0.7226 - 2.988 0.513 - 529.6 1 2 0 0.001 11 0 0 0 6.74E+06 3.15E+07 - - - 7.3687 0.9999 221125_WJC_METTL3_EV_vs_WT_F06.15071.15071.3 3.17E-05 14/48 K.SHLEVPLEENVNR.R "sp|Q96CT7|CC124_HUMAN,tr|M0R2F5|M0R2F5_HUMAN" 2 1534.774 1.02 84096 15071 3 1534.777091 512.5986 Coiled-coil domain-containing protein 124 OS=Homo sapiens OX=9606 GN=CCDC124 PE=1 SV=1 4.75 2579 - 1.51E+06 - - - 2.0335 - 2.646 0.446 - 392.4 1 2 0 0.0031 13 0 0 0 1.03E+08 1.01E+08 - - - 6.1498 0.9969 221125_WJC_METTL3_EV_vs_WT_F06.15074.15074.3 0.0024 Nov-68 K.YVHYEIDAC[160.03]MDSEAPGSK[136.11].D "sp|Q86U44|MTA70_HUMAN,tr|H0YFV6|H0YFV6_HUMAN" 2 2078.8805 0.18 84099 15074 3 2078.868981 693.9674 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 4.31 2579.3 - 1.09E+06 - - - -5.5371 - 2.207 0.396 - 105.3 1 2 0 -0.0115 18 0 0 0 1.69E+06 9.24E+06 - - - 4.9231 0.9999 221125_WJC_METTL3_EV_vs_WT_F06.15076.15076.3 0.000533 14/56 K.IQLSNQELLGDDQKK.V "sp|Q5VT06|CE350_HUMAN,tr|H0Y7F7|H0Y7F7_HUMAN,tr|Q5T2X4|Q5T2X4_HUMAN" 3 1727.9054 2.23 84101 15076 3 1727.908684 576.9757 Centrosome-associated protein 350 OS=Homo sapiens OX=9606 GN=CEP350 PE=1 SV=1 4.56 2579.5 - 937358 - - - 1.9133 - 2.454 0.426 - 273.1 1 2 0 0.0033 15 0 0 0 5.98E+06 2.68E+06 - - - 5.631 0.9999 221125_WJC_METTL3_EV_vs_WT_F06.15079.15079.3 3.69E-07 17/56 R.APSKPWSQVDEATIR.A sp|Q9H6S0|YTDC2_HUMAN 1 1683.858 3.36 84104 15079 3 1683.863122 562.2933 3'-5' RNA helicase YTHDC2 OS=Homo sapiens OX=9606 GN=YTHDC2 PE=1 SV=2 6.11 2579.9 - 662505 - - - 3.0216 - 3.108 0.499 - 460.1 1 2 0 0.0051 15 0 0 0 3.58E+07 1.07E+07 - - - 7.0609 1 221125_WJC_METTL3_EV_vs_WT_F06.15081.15081.4 2.00E-06 16/84 K.THINIVVIGHVDSGK[136.11].S "sp|Q05639|EF1A2_HUMAN,sp|P68104|EF1A1_HUMAN,sp|Q5VTE0|EF1A3_HUMAN,tr|A0A2R8Y488|A0A2R8Y488_HUMAN,tr|A0A2R8YDN5|A0A2R8YDN5_HUMAN,tr|A0A7I2V659|A0A7I2V659_HUMAN,tr|A0A7I2V3H3|A0A7I2V3H3_HUMAN,tr|Q5JR01|Q5JR01_HUMAN,tr|A0A2U3TZH3|A0A2U3TZH3_HUMAN,tr|A0A7I2V5N4|A0A7I2V5N4_HUMAN,tr|A0A087WVQ9|A0A087WVQ9_HUMAN,tr|A6PW80|A6PW80_HUMAN,tr|A0A087WV01|A0A087WV01_HUMAN,tr|A0A2R8Y660|A0A2R8Y660_HUMAN,tr|A0A6Q8PFK6|A0A6Q8PFK6_HUMAN" 15 1595.8875 0.32 84106 15081 4 1595.888283 399.9791 Elongation factor 1-alpha 2 OS=Homo sapiens OX=9606 GN=EEF1A2 PE=1 SV=1 6.61 2580.2 - 406229 - - - 0.4969 - 3.38 0.504 - 361.4 1 2 0 0.0008 15 0 0 0 7.97E+05 2.47E+06 - - - 4.0484 1 221125_WJC_METTL3_EV_vs_WT_F06.15092.15092.3 8.87E-08 16/48 K.SHLEVPLEENVNR[166.11].R "sp|Q96CT7|CC124_HUMAN,tr|M0R2F5|M0R2F5_HUMAN" 2 1544.7822 1.03 84116 15092 3 1544.785163 515.9347 Coiled-coil domain-containing protein 124 OS=Homo sapiens OX=9606 GN=CCDC124 PE=1 SV=1 4.75 2581.4 - 3.63E+06 - - - 1.8922 - 3.161 0.565 - 463.3 1 2 0 0.0029 13 0 0 0 9.64E+07 9.36E+07 - - - 7.9588 0.9996 221125_WJC_METTL3_EV_vs_WT_F06.15094.15094.3 9.70E-08 14/56 R.APSK[136.11]PWSQVDEATIR[166.11].A sp|Q9H6S0|YTDC2_HUMAN 1 1701.8805 1.06 84118 15094 3 1701.888291 568.3008 3'-5' RNA helicase YTHDC2 OS=Homo sapiens OX=9606 GN=YTHDC2 PE=1 SV=2 6.11 2581.5 - 924745 - - - 4.5755 - 2.682 0.489 - 286.3 1 2 0 0.0078 15 0 0 0 4.28E+06 4.05E+06 - - - 6.564 1 221125_WJC_METTL3_EV_vs_WT_F06.15095.15095.3 3.68E-05 19/56 R.QQQQIEAQQQLLATK.E "sp|Q13625|ASPP2_HUMAN,tr|H7C5L8|H7C5L8_HUMAN" 2 1753.9323 0.62 84119 15095 3 1753.934918 585.6514 Apoptosis-stimulating of p53 protein 2 OS=Homo sapiens OX=9606 GN=TP53BP2 PE=1 SV=2 6 2581.7 - 781088 - - - 1.5143 - 3.151 0.462 - 781.4 1 2 0 0.0027 15 0 0 0 5.92E+06 9.54E+06 - - - 6.6849 1 221125_WJC_METTL3_EV_vs_WT_F06.15096.15096.3 0.000273 15/56 R.SFDVNK[136.11]PGC[160.03]EVDDLK[136.11].G "sp|Q2VIR3|IF2GL_HUMAN,sp|P41091|IF2G_HUMAN" 2 1737.8215 0.92 84120 15096 3 1737.822169 580.2811 Eukaryotic translation initiation factor 2 subunit 3B OS=Homo sapiens OX=9606 GN=EIF2S3B PE=2 SV=2 4.23 2581.8 - 764786 - - - 0.4132 - 2.497 0.539 - 150 1 2 0 0.0007 15 0 0 0 4.26E+07 4.62E+07 - - - 6.9369 1 221125_WJC_METTL3_EV_vs_WT_F06.15097.15097.3 8.71E-07 13/40 R.R[166.11]QSC[160.03]YLC[160.03]DLPR[166.11].M "sp|Q7Z5L9|I2BP2_HUMAN,sp|Q9H1B7|I2BPL_HUMAN" 2 1486.6924 1.32 84121 15097 3 1486.691211 496.5714 Interferon regulatory factor 2-binding protein 2 OS=Homo sapiens OX=9606 GN=IRF2BP2 PE=1 SV=2 8.06 2581.9 - 604450 - - - -0.7951 - 2.389 0.544 - 229 1 2 0 -0.0012 11 0 0 0 3.03E+07 2.30E+07 - - - 7.0787 1 221125_WJC_METTL3_EV_vs_WT_F06.15099.15099.4 0.00101 19/78 K.LGAQLADLHLDNK[136.11]K[136.11].L "sp|Q9HA64|KT3K_HUMAN,tr|I3L2G3|I3L2G3_HUMAN,tr|I3L139|I3L139_HUMAN" 3 1550.8751 0.33 84123 15099 4 1550.875441 388.7261 Ketosamine-3-kinase OS=Homo sapiens OX=9606 GN=FN3KRP PE=1 SV=2 6.75 2582.2 - 490815 - - - 0.1934 - 3.262 0.464 - 411.7 1 2 0 0.0003 14 0 0 0 9.22E+06 2.78E+07 - - - 3.6949 0.9989 221125_WJC_METTL3_EV_vs_WT_F06.15100.15100.3 3.98E-05 16/64 K.HQAFEAEVQANSGAIVK.L "sp|Q13813|SPTN1_HUMAN,tr|A0A0D9SFF6|A0A0D9SFF6_HUMAN,tr|A0A0D9SF54|A0A0D9SF54_HUMAN,tr|A0A0D9SGF6|A0A0D9SGF6_HUMAN,tr|A0A5F9ZHC3|A0A5F9ZHC3_HUMAN" 5 1797.901 1.1 84124 15100 3 1797.913507 600.3076 "Spectrin alpha chain, non-erythrocytic 1 OS=Homo sapiens OX=9606 GN=SPTAN1 PE=1 SV=3" 5.4 2582.3 - 440025 - - - 6.9776 - 3.177 0.506 - 263.4 1 2 0 0.0125 17 0 0 0 4.06E+06 3.70E+06 - - - 7.0982 0.9999 221125_WJC_METTL3_EV_vs_WT_F06.15102.15102.3 1.79E-05 Nov-48 R.VKPLQDQNELFGK.L sp|Q12874|SF3A3_HUMAN 1 1514.8093 2.16 84125 15102 3 1514.809755 505.9437 Splicing factor 3A subunit 3 OS=Homo sapiens OX=9606 GN=SF3A3 PE=1 SV=1 6.04 2582.5 - 2.20E+06 - - - 0.305 - 2.089 0.432 - 104.5 1 2 0 0.0005 13 0 0 0 1.36E+07 6.31E+06 - - - 5.3536 0.9888 221125_WJC_METTL3_EV_vs_WT_F06.15103.15103.4 0.0961 Oct-90 R.VGHSTAHDEIIPMSIR.K "sp|Q14165|MLEC_HUMAN,tr|H0YG07|H0YG07_HUMAN,tr|F5H1S8|F5H1S8_HUMAN" 3 1761.8832 1.32 84126 15103 4 1761.884688 441.4781 Malectin OS=Homo sapiens OX=9606 GN=MLEC PE=1 SV=1 5.99 2582.6 - 243999 - - - 0.8428 - 1.79 0.195 - 92.1 1 2 0 0.0015 16 0 0 0 4.02E+06 3.05E+06 - - - 1.128 0.9998 221125_WJC_METTL3_EV_vs_WT_F06.15105.15105.3 1.04E-05 Nov-36 K.NYGFVHIEDK[136.11].T "sp|Q9BWF3|RBM4_HUMAN,sp|Q9BQ04|RBM4B_HUMAN,tr|E9PM61|E9PM61_HUMAN,tr|D6R9K7|D6R9K7_HUMAN,tr|J3QRR5|J3QRR5_HUMAN,tr|E9PB51|E9PB51_HUMAN,tr|U3KQD5|U3KQD5_HUMAN,tr|E9PLB0|E9PLB0_HUMAN" 8 1228.5968 1.53 84128 15105 3 1228.596381 410.5395 RNA-binding protein 4 OS=Homo sapiens OX=9606 GN=RBM4 PE=1 SV=1 5.32 2582.8 - 1.73E+06 - - - -0.3313 - 2.215 0.316 - 248.2 1 2 0 -0.0004 10 0 0 0 2.08E+07 1.36E+07 - - - 4.3855 0.9999 221125_WJC_METTL3_EV_vs_WT_F06.15106.15106.3 0.0338 Dec-40 R.RQSC[160.03]YLC[160.03]DLPR.M "sp|Q7Z5L9|I2BP2_HUMAN,sp|Q9H1B7|I2BPL_HUMAN" 2 1466.6759 1.05 84129 15106 3 1466.677433 489.8992 Interferon regulatory factor 2-binding protein 2 OS=Homo sapiens OX=9606 GN=IRF2BP2 PE=1 SV=2 8.06 2582.9 - 1.29E+06 - - - 1.0773 - 2.317 0.436 - 232.6 1 2 0 0.0016 11 0 0 0 3.21E+07 3.05E+07 - - - 5.7876 0.9999 221125_WJC_METTL3_EV_vs_WT_F06.15107.15107.2 0.000327 14/22 K.NAGVEGSLIVEK.L "sp|P10809|CH60_HUMAN,tr|A0A7I2V2X6|A0A7I2V2X6_HUMAN,tr|A0A7I2YQK6|A0A7I2YQK6_HUMAN,tr|A0A7I2V599|A0A7I2V599_HUMAN" 4 1214.6507 1.35 84130 15107 2 1214.65017 608.3326 "60 kDa heat shock protein, mitochondrial OS=Homo sapiens OX=9606 GN=HSPD1 PE=1 SV=2" 4.53 2583 - 1.22E+06 - - - -0.4092 - 2.648 0.48 - 682.8 1 2 0 -0.0005 12 0 0 0 2.44E+07 1.80E+07 - - - 5.1484 0.9999 221125_WJC_METTL3_EV_vs_WT_F06.15108.15108.2 0.000124 13/22 K.NAGVEGSLIVEK[136.11].L "sp|P10809|CH60_HUMAN,tr|A0A7I2V2X6|A0A7I2V2X6_HUMAN,tr|A0A7I2YQK6|A0A7I2YQK6_HUMAN,tr|A0A7I2V599|A0A7I2V599_HUMAN" 4 1222.6649 1.35 84131 15108 2 1222.664147 612.3397 "60 kDa heat shock protein, mitochondrial OS=Homo sapiens OX=9606 GN=HSPD1 PE=1 SV=2" 4.53 2583.1 - 982492 - - - -0.5889 - 2.5 0.475 - 545 1 2 0 -0.0007 12 0 0 0 2.44E+07 1.80E+07 - - - 4.96 0.9987 221125_WJC_METTL3_EV_vs_WT_F06.15110.15110.3 0.0136 14/36 K.QKVEHIEWFR.N sp|Q92665|RT31_HUMAN 1 1370.7095 1.65 84133 15110 3 1370.711406 457.9104 "28S ribosomal protein S31, mitochondrial OS=Homo sapiens OX=9606 GN=MRPS31 PE=1 SV=3" 6.76 2583.4 - 849858 - - - 1.3767 - 2.39 0.307 - 405.6 1 2 1 0.0019 10 0 0 0 2.01E+07 1.21E+07 - - - 4.5068 0.9997 221125_WJC_METTL3_EV_vs_WT_F06.15112.15112.4 5.01E-06 16/96 R.VKGVTIVKPIVYGNVAR.Y "sp|O95619|YETS4_HUMAN,tr|F8W1B9|F8W1B9_HUMAN,tr|F8W0J4|F8W0J4_HUMAN" 3 1812.0985 0.72 84135 15112 4 1812.098022 454.0319 YEATS domain-containing protein 4 OS=Homo sapiens OX=9606 GN=YEATS4 PE=1 SV=1 10.29 2583.5 - 757120 - - - -0.2853 - 2.279 0.444 - 152.2 1 2 1 -0.0005 17 0 0 0 3.03E+06 4.20E+06 - - - 3.3764 0.9998 221125_WJC_METTL3_EV_vs_WT_F06.15113.15113.3 0.000122 18/40 R.MVNHFIAEFKR.K "sp|P11142|HSP7C_HUMAN,tr|A8K7Q2|A8K7Q2_HUMAN,tr|E9PKE3|E9PKE3_HUMAN,tr|E9PN89|E9PN89_HUMAN" 4 1390.718 0.21 84136 15113 3 1390.718723 464.5799 Heat shock cognate 71 kDa protein OS=Homo sapiens OX=9606 GN=HSPA8 PE=1 SV=1 8.52 2583.6 - 710266 - - - 0.5371 - 2.166 0.327 - 392.3 1 2 0 0.0007 11 0 0 0 6.74E+06 3.15E+07 - - - 4.3811 0.9998 221125_WJC_METTL3_EV_vs_WT_F06.15115.15115.2 0.738 13/24 K.SHLEVPLEENVNR[166.11].R "sp|Q96CT7|CC124_HUMAN,tr|M0R2F5|M0R2F5_HUMAN" 2 1544.7822 0.84 84138 15115 2 1544.783743 773.3984 Coiled-coil domain-containing protein 124 OS=Homo sapiens OX=9606 GN=CCDC124 PE=1 SV=1 4.75 2583.9 - 569266 - - - 0.973 - 2.536 0.392 - 517.5 1 2 0 0.0015 13 0 0 0 7.03E+06 8.36E+06 - - - 4.3242 0.9999 221125_WJC_METTL3_EV_vs_WT_F06.15117.15117.3 0.000406 16/56 R.QQQQIEAQQQLLATK[136.11].E "sp|Q13625|ASPP2_HUMAN,tr|H7C5L8|H7C5L8_HUMAN" 2 1761.9465 0.13 84140 15117 3 1761.948209 588.3228 Apoptosis-stimulating of p53 protein 2 OS=Homo sapiens OX=9606 GN=TP53BP2 PE=1 SV=2 6 2584.2 - 484539 - - - 0.9915 - 2.003 0.454 - 326 1 2 0 0.0017 15 0 0 0 5.92E+06 4.53E+07 - - - 5.4138 1 221125_WJC_METTL3_EV_vs_WT_F06.15120.15120.3 3.65E-06 16/56 R.SFDVNKPGC[160.03]EVDDLK.G "sp|Q2VIR3|IF2GL_HUMAN,sp|P41091|IF2G_HUMAN" 2 1721.7931 0.92 84141 15120 3 1721.793157 574.9383 Eukaryotic translation initiation factor 2 subunit 3B OS=Homo sapiens OX=9606 GN=EIF2S3B PE=2 SV=2 4.23 2584.6 - 4.05E+06 - - - 0.0616 - 2.897 0.622 - 183.7 1 2 0 0.0001 15 0 0 0 4.26E+07 4.62E+07 - - - 8.2502 1 221125_WJC_METTL3_EV_vs_WT_F06.15122.15122.3 1.62E-07 Dec-48 R.KLVTDQNISENWR.V "sp|P24666|PPAC_HUMAN,tr|F2Z2Q9|F2Z2Q9_HUMAN,tr|G5E9R5|G5E9R5_HUMAN" 3 1601.8162 1.2 84143 15122 3 1601.8168 534.946 Low molecular weight phosphotyrosine protein phosphatase OS=Homo sapiens OX=9606 GN=ACP1 PE=1 SV=3 6.07 2584.7 - 6.54E+06 - - - 0.3939 - 2.569 0.592 - 196.7 1 2 0 0.0006 13 0 0 0 5.05E+07 4.21E+07 - - - 7.6982 0.9947 221125_WJC_METTL3_EV_vs_WT_F06.15124.15124.3 0.00464 Oct-60 R.SSTPLPTISSSAENTR.Q "sp|P42166|LAP2A_HUMAN,sp|P42167|LAP2B_HUMAN,tr|G5E972|G5E972_HUMAN,tr|H0YJH7|H0YJH7_HUMAN" 4 1646.8111 1.6 84145 15124 3 1646.815573 549.9443 "Lamina-associated polypeptide 2, isoform alpha OS=Homo sapiens OX=9606 GN=TMPO PE=1 SV=2" 5.72 2584.8 - 1.52E+06 - - - 2.6894 - 1.79 0.26 - 105.7 1 2 0 0.0044 16 0 0 0 2.38E+07 1.48E+07 - - - 2.9314 0.9997 221125_WJC_METTL3_EV_vs_WT_F06.15126.15126.4 0.000102 16/78 K.LGAQLADLHLDNKK.L "sp|Q9HA64|KT3K_HUMAN,tr|I3L2G3|I3L2G3_HUMAN,tr|I3L139|I3L139_HUMAN" 3 1534.8467 0.33 84147 15126 4 1534.845934 384.719 Ketosamine-3-kinase OS=Homo sapiens OX=9606 GN=FN3KRP PE=1 SV=2 6.75 2585 - 1.00E+06 - - - -0.5258 - 2.719 0.343 - 287 1 2 0 -0.0008 14 0 0 0 9.22E+06 2.78E+07 - - - 2.5753 0.9998 221125_WJC_METTL3_EV_vs_WT_F06.15128.15128.2 0.000123 24-Nov K.SHLEVPLEENVNR.R "sp|Q96CT7|CC124_HUMAN,tr|M0R2F5|M0R2F5_HUMAN" 2 1534.774 0.84 84149 15128 2 1534.773655 768.3943 Coiled-coil domain-containing protein 124 OS=Homo sapiens OX=9606 GN=CCDC124 PE=1 SV=1 4.75 2585.1 - 710468 - - - -0.2052 - 2.356 0.391 - 368.8 1 2 0 -0.0003 13 0 0 0 7.03E+06 8.36E+06 - - - 4.1283 0.897 221125_WJC_METTL3_EV_vs_WT_F06.15129.15129.3 0.811 Jun-36 R.QSHDYNWSFK.Y "sp|O15270|SPTC2_HUMAN,tr|H0YJV2|H0YJV2_HUMAN" 2 1310.568 0.76 84150 15129 3 1310.568708 437.8633 Serine palmitoyltransferase 2 OS=Homo sapiens OX=9606 GN=SPTLC2 PE=1 SV=1 6.74 2585.3 - 453956 - - - 0.5402 - 1.149 0.133 - 43.8 1 2 0 0.0007 10 0 0 0 2.46E+06 3.25E+06 - - - 0.4282 0.9998 221125_WJC_METTL3_EV_vs_WT_F06.15131.15131.2 2.81E-07 28-Nov R.QQQQIEAQQQLLATK.E "sp|Q13625|ASPP2_HUMAN,tr|H7C5L8|H7C5L8_HUMAN" 2 1753.9323 2.12 84152 15131 2 1753.935339 877.9734 Apoptosis-stimulating of p53 protein 2 OS=Homo sapiens OX=9606 GN=TP53BP2 PE=1 SV=2 6 2585.5 - 367910 - - - 1.7543 - 2.42 0.533 - 227.8 1 2 0 0.0031 15 0 0 0 2.81E+06 1.32E+06 - - - 5.1496 1 221125_WJC_METTL3_EV_vs_WT_F06.15136.15136.3 2.80E-09 27/76 R.LQQQAALSPTTAPAVSSVSK.Q "sp|Q8WXI9|P66B_HUMAN,tr|A0A0U1RRM1|A0A0U1RRM1_HUMAN,tr|A0A0U1RR30|A0A0U1RR30_HUMAN" 3 1983.0637 1.89 84155 15136 3 1983.064923 662.0285 Transcriptional repressor p66-beta OS=Homo sapiens OX=9606 GN=GATAD2B PE=1 SV=1 8.75 2586.1 - 2.15E+06 - - - 0.6319 - 4.263 0.585 - 736.3 1 2 0 0.0013 20 0 0 0 1.09E+09 5.76E+08 - - - 8.5795 1 221125_WJC_METTL3_EV_vs_WT_F06.15138.15138.3 2.92E-05 26/76 R.LQQQAALSPTTAPAVSSVSK[136.11].Q "sp|Q8WXI9|P66B_HUMAN,tr|A0A0U1RRM1|A0A0U1RRM1_HUMAN,tr|A0A0U1RR30|A0A0U1RR30_HUMAN" 3 1991.0779 1.89 84157 15138 3 1991.078464 664.6999 Transcriptional repressor p66-beta OS=Homo sapiens OX=9606 GN=GATAD2B PE=1 SV=1 8.75 2586.3 - 1.18E+06 - - - 0.2983 - 3.554 0.421 - 650.2 1 2 0 0.0006 20 0 0 0 1.09E+09 5.76E+08 - - - 6.3099 0.9999 221125_WJC_METTL3_EV_vs_WT_F06.15141.15141.3 1.34E-09 20/72 R.LADSGDGAGPSPEEK[136.11]DFLK[136.11].T sp|Q92917|GPKOW_HUMAN 1 1947.9397 1.92 84160 15141 3 1947.94109 650.3205 G-patch domain and KOW motifs-containing protein OS=Homo sapiens OX=9606 GN=GPKOW PE=1 SV=2 4.11 2586.6 - 853343 - - - 0.7382 - 2.945 0.564 - 349 1 2 1 0.0014 19 0 0 0 1.47E+07 7.67E+06 - - - 7.4813 0.9998 221125_WJC_METTL3_EV_vs_WT_F06.15143.15143.2 1.60E-09 17/38 R.LQQQAALSPTTAPAVSSVSK.Q "sp|Q8WXI9|P66B_HUMAN,tr|A0A0U1RRM1|A0A0U1RRM1_HUMAN,tr|A0A0U1RR30|A0A0U1RR30_HUMAN" 3 1983.0637 1.88 84162 15143 2 1983.067423 992.5391 Transcriptional repressor p66-beta OS=Homo sapiens OX=9606 GN=GATAD2B PE=1 SV=1 8.75 2586.9 - 437580 - - - 1.8925 - 3.333 0.455 - 635.2 1 2 0 0.0038 20 0 0 0 4.18E+08 2.23E+08 - - - 5.3602 0.9998 221125_WJC_METTL3_EV_vs_WT_F06.15148.15148.3 5.01E-06 Dec-40 K.IRLENEIQTYR.S "sp|P13645|K1C10_HUMAN,tr|A0A1B0GVI3|A0A1B0GVI3_HUMAN" 2 1433.7627 304.29 84165 15148 3 1433.762083 478.9282 "Keratin, type I cytoskeletal 10 OS=Homo sapiens OX=9606 GN=KRT10 PE=1 SV=6" 6.14 2587.6 - 9.70E+06 - - - -0.4143 - 2.298 0.48 - 261.2 1 2 1 -0.0006 11 0 0 0 4.51E+08 1.48E+06 - - - 6.255 0.9999 221125_WJC_METTL3_EV_vs_WT_F06.15152.15152.4 4.80E-05 15/84 R.FIIQSEKPPHYLESR.V "sp|P14735|IDE_HUMAN,tr|A0A3B3ISG5|A0A3B3ISG5_HUMAN,tr|A0A7I2V3K9|A0A7I2V3K9_HUMAN,tr|A0A7I2V3E3|A0A7I2V3E3_HUMAN,tr|A0A7I2V610|A0A7I2V610_HUMAN,tr|A0A7I2YQV5|A0A7I2YQV5_HUMAN,tr|B3KSB8|B3KSB8_HUMAN,tr|A0A7I2V2P6|A0A7I2V2P6_HUMAN" 8 1842.9628 2.43 84169 15152 4 1842.963432 461.748 Insulin-degrading enzyme OS=Homo sapiens OX=9606 GN=IDE PE=1 SV=4 6.76 2587.8 - 1.56E+06 - - - 0.3245 - 2.709 0.422 - 220 1 2 0 0.0006 15 0 0 0 2.07E+07 8.51E+06 - - - 3.2555 1 221125_WJC_METTL3_EV_vs_WT_F06.15153.15153.3 5.94E-08 15/72 K.AYSDPSTGEPATYGELQQR.C "sp|Q15149|PLEC_HUMAN,tr|H0YDN1|H0YDN1_HUMAN" 2 2068.9338 5.81 84170 15153 3 2068.937116 690.6519 Plectin OS=Homo sapiens OX=9606 GN=PLEC PE=1 SV=3 4.14 2587.9 - 1.11E+06 - - - 1.6134 - 2.905 0.596 - 220.9 1 2 0 0.0033 19 0 0 0 2.52E+07 4.33E+06 - - - 7.8039 1 221125_WJC_METTL3_EV_vs_WT_F06.15155.15155.2 1.56E-14 17/32 K.NATDLQNSSMSEEELTK.A "sp|P40855|PEX19_HUMAN,tr|H0YJ60|H0YJ60_HUMAN,tr|Q5QNY5|Q5QNY5_HUMAN" 3 1895.8419 999 84172 15155 2 1895.842636 948.9282 Peroxisomal biogenesis factor 19 OS=Homo sapiens OX=9606 GN=PEX19 PE=1 SV=1 4 2588.2 - 534940 - - - 0.4141 - 3.784 0.758 - 1050.5 1 2 0 0.0008 17 0 0 0 4.14E+06 0.00E+00 - - - 7.9111 0.9958 221125_WJC_METTL3_EV_vs_WT_F06.15156.15156.4 0.0929 14/84 K.HLAGLGLTEAIDKNK.A "sp|P50454|SERPH_HUMAN,tr|E9PKH2|E9PKH2_HUMAN,tr|E9PJH8|E9PJH8_HUMAN" 3 1578.873 1.94 84173 15156 4 1578.873324 395.7255 Serpin H1 OS=Homo sapiens OX=9606 GN=SERPINH1 PE=1 SV=2 6.75 2588.3 - 454472 - - - 0.2331 - 2.272 0.288 - 145.2 1 2 1 0.0004 15 0 0 0 3.52E+06 1.82E+06 - - - 2.0263 0.8211 221125_WJC_METTL3_EV_vs_WT_F06.15157.15157.2 0.0681 28-Jun R.R[166.11]AEQDSTTVAAFASS.L "sp|Q86U44|MTA70_HUMAN,tr|F5H6D8|F5H6D8_HUMAN,tr|H0YFV6|H0YFV6_HUMAN,tr|B4DTN4|B4DTN4_HUMAN" 4 1549.7248 0.05 84174 15157 2 1549.723975 775.8697 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 4.37 2588.5 - 386024 - - - -0.5227 - 1.18 0.259 - 61.6 1 1 0 -0.0008 15 0 0 0 3.25E+05 6.86E+06 - - - 1.3606 1 221125_WJC_METTL3_EV_vs_WT_F06.15158.15158.2 1.67E-10 17/34 R.SSYYVVSGNDPAAEEPSR[166.11].A sp|P46821|MAP1B_HUMAN 1 1936.8678 0.66 84175 15158 2 1936.86591 969.4412 Microtubule-associated protein 1B OS=Homo sapiens OX=9606 GN=MAP1B PE=1 SV=2 4.14 2588.6 - 349061 - - - -0.9861 - 3.14 0.745 - 515.7 1 2 0 -0.0019 18 0 0 0 3.37E+06 5.10E+06 - - - 7.3561 1 221125_WJC_METTL3_EV_vs_WT_F06.15164.15164.2 1.67E-06 16/20 K.IRLENEIQTYR.S "sp|P13645|K1C10_HUMAN,tr|A0A1B0GVI3|A0A1B0GVI3_HUMAN" 2 1433.7627 999 84180 15164 2 1433.761699 717.8886 "Keratin, type I cytoskeletal 10 OS=Homo sapiens OX=9606 GN=KRT10 PE=1 SV=6" 6.14 2589.1 - 3.97E+06 - - - -0.6821 - 3.1 0.546 - 337.8 1 2 1 -0.001 11 0 0 0 1.20E+08 0.00E+00 - - - 6.1342 1 221125_WJC_METTL3_EV_vs_WT_F06.15168.15168.2 2.18E-11 21/38 R.LQQQAALSPTTAPAVSSVSK[136.11].Q "sp|Q8WXI9|P66B_HUMAN,tr|A0A0U1RRM1|A0A0U1RRM1_HUMAN,tr|A0A0U1RR30|A0A0U1RR30_HUMAN" 3 1991.0779 1.88 84184 15168 2 1991.072379 996.5462 Transcriptional repressor p66-beta OS=Homo sapiens OX=9606 GN=GATAD2B PE=1 SV=1 8.75 2589.5 - 1.26E+06 - - - -2.7578 - 3.917 0.618 - 1194.1 1 2 0 -0.0055 20 0 0 0 4.18E+08 2.23E+08 - - - 6.9605 0.9877 221125_WJC_METTL3_EV_vs_WT_F06.15178.15178.3 2.33E-06 19/56 L.TTAEVVVTEIPKEEK.D "sp|P10809|CH60_HUMAN,tr|A0A7I2V2X6|A0A7I2V2X6_HUMAN,tr|A0A7I2YQK6|A0A7I2YQK6_HUMAN" 3 1671.8931 1.41 84192 15178 3 1671.89378 558.305 "60 kDa heat shock protein, mitochondrial OS=Homo sapiens OX=9606 GN=HSPD1 PE=1 SV=2" 4.49 2590.4 - 5.07E+06 - - - 0.4175 - 2.773 0.494 - 419.3 1 1 1 0.0007 15 0 0 0 1.12E+08 7.90E+07 - - - 6.7088 0.9999 221125_WJC_METTL3_EV_vs_WT_F06.15179.15179.2 3.42E-05 13/20 R.QGVDADINGLR.Q "sp|P35527|K1C9_HUMAN,tr|K7EQQ3|K7EQQ3_HUMAN" 2 1156.5837 999 84193 15179 2 1156.581917 579.2991 "Keratin, type I cytoskeletal 9 OS=Homo sapiens OX=9606 GN=KRT9 PE=1 SV=3" 4.21 2590.4 - 3.66E+06 - - - -1.4984 - 2.636 0.548 - 1022.6 1 2 0 -0.0017 11 0 0 0 5.20E+07 0.00E+00 - - - 5.7101 0.9999 221125_WJC_METTL3_EV_vs_WT_F06.15180.15180.3 8.01E-08 18/68 R.SPLLAGGSPPQPVVPAHK.D "sp|Q8NFH5|NUP35_HUMAN,tr|F8WCF5|F8WCF5_HUMAN,tr|F8WEL4|F8WEL4_HUMAN,tr|C9JIY9|C9JIY9_HUMAN,tr|C9IYQ7|C9IYQ7_HUMAN" 5 1750.973 3.01 84194 15180 3 1750.967437 584.6649 Nucleoporin NUP35 OS=Homo sapiens OX=9606 GN=NUP35 PE=1 SV=1 8.49 2590.6 - 2.67E+06 - - - -3.1794 - 3.33 0.471 - 322.3 1 2 0 -0.0056 18 0 0 0 5.39E+08 1.79E+08 - - - 6.7852 1 221125_WJC_METTL3_EV_vs_WT_F06.15181.15181.3 3.96E-08 19/60 K.KMEDSVGC[160.03]LETAEEVK.R sp|P35579|MYH9_HUMAN 1 1823.8281 0.72 84195 15181 3 1823.823271 608.95 Myosin-9 OS=Homo sapiens OX=9606 GN=MYH9 PE=1 SV=4 4.25 2590.7 - 1.58E+06 - - - -2.6565 - 2.864 0.574 - 379.8 1 2 0 -0.0048 16 0 0 0 3.05E+07 4.24E+07 - - - 7.638 0.9982 221125_WJC_METTL3_EV_vs_WT_F06.15182.15182.4 0.00185 Nov-84 K.VIILSLDR[166.11]SDEDK[136.11]EK[136.11].A "sp|P78344|IF4G2_HUMAN,tr|E9PKF8|E9PKF8_HUMAN,tr|H0Y3P2|H0Y3P2_HUMAN,tr|D3DQV9|D3DQV9_HUMAN" 4 1784.973 2.59 84196 15182 4 1784.9692 447.2505 Eukaryotic translation initiation factor 4 gamma 2 OS=Homo sapiens OX=9606 GN=EIF4G2 PE=1 SV=1 4.44 2590.8 - 1.58E+06 - - - -2.1367 - 1.866 0.366 - 90.8 1 2 2 -0.0038 15 0 0 0 2.58E+08 9.98E+07 - - - 2.6338 0.9995 221125_WJC_METTL3_EV_vs_WT_F06.15183.15183.3 0.000327 13/40 R.NRPHIC[160.03]SFWVK.G "sp|Q9NW64|RBM22_HUMAN,tr|E5RJW4|E5RJW4_HUMAN" 2 1442.7241 2.77 84197 15183 3 1442.718249 481.9153 Pre-mRNA-splicing factor RBM22 OS=Homo sapiens OX=9606 GN=RBM22 PE=1 SV=1 9.51 2590.9 - 754683 - - - -4.0722 - 2.39 0.412 - 261.1 1 2 0 -0.0059 11 0 0 0 4.15E+07 1.50E+07 - - - 5.607 0.9994 221125_WJC_METTL3_EV_vs_WT_F06.15189.15189.3 0.000345 15/40 K.TRLEQEIATYR.R "sp|Q04695|K1C17_HUMAN,sp|P02533|K1C14_HUMAN,sp|P35900|K1C20_HUMAN,sp|P08779|K1C16_HUMAN,sp|P19012|K1C15_HUMAN,sp|P13646|K1C13_HUMAN,tr|A0A3B3IS58|A0A3B3IS58_HUMAN,tr|F5GWP8|F5GWP8_HUMAN,tr|K7ERE3|K7ERE3_HUMAN,tr|A8MT21|A8MT21_HUMAN" 10 1378.7205 100.22 84201 15189 3 1378.720202 460.5808 "Keratin, type I cytoskeletal 17 OS=Homo sapiens OX=9606 GN=KRT17 PE=1 SV=2" 5.81 2591.5 - 3.11E+06 - - - -0.2002 - 2.787 0.311 - 403.2 1 2 1 -0.0003 11 0 0 0 5.47E+08 5.45E+06 - - - 4.919 0.9995 221125_WJC_METTL3_EV_vs_WT_F06.15190.15190.4 0.000179 14/78 R.KYFTC[160.03]DEGHGIFVR.Q "sp|Q14203|DCTN1_HUMAN,tr|C9JTE5|C9JTE5_HUMAN,tr|A0A804CDA6|A0A804CDA6_HUMAN,tr|C9JJN7|C9JJN7_HUMAN,tr|E7EX90|E7EX90_HUMAN,tr|C9JJD0|C9JJD0_HUMAN,tr|A0A7P0Z4C3|A0A7P0Z4C3_HUMAN,tr|Q6AWB1|Q6AWB1_HUMAN,tr|C9JZA4|C9JZA4_HUMAN,tr|E9PCY0|E9PCY0_HUMAN,tr|C9JKG6|C9JKG6_HUMAN" 11 1727.809 2.45 84202 15190 4 1727.801461 432.9595 Dynactin subunit 1 OS=Homo sapiens OX=9606 GN=DCTN1 PE=1 SV=3 6.74 2591.7 - 1.67E+06 - - - -4.3494 - 2.619 0.451 - 211.2 1 2 0 -0.0075 14 0 0 0 2.31E+07 9.43E+06 - - - 3.4998 0.9991 221125_WJC_METTL3_EV_vs_WT_F06.15192.15192.4 0.0127 Oct-66 R.FHWEQDQIAHMK[136.11].N sp|Q9UG63|ABCF2_HUMAN 1 1576.7336 0.27 84204 15192 4 1576.731274 395.1907 ATP-binding cassette sub-family F member 2 OS=Homo sapiens OX=9606 GN=ABCF2 PE=1 SV=2 5.99 2591.9 - 954510 - - - -1.4955 - 1.853 0.305 - 110.4 1 2 0 -0.0024 12 0 0 0 2.37E+06 8.74E+06 - - - 2.1135 1 221125_WJC_METTL3_EV_vs_WT_F06.15193.15193.2 6.50E-16 19/36 K.AYSDPSTGEPATYGELQQR.C "sp|Q15149|PLEC_HUMAN,tr|H0YDN1|H0YDN1_HUMAN" 2 2068.9338 3.6 84205 15193 2 2068.931855 1035.4742 Plectin OS=Homo sapiens OX=9606 GN=PLEC PE=1 SV=3 4.14 2592.1 - 851027 - - - -0.9295 - 3.529 0.728 - 660.8 1 2 0 -0.0019 19 0 0 0 1.57E+07 4.37E+06 - - - 7.5177 1 221125_WJC_METTL3_EV_vs_WT_F06.15205.15205.2 0.00217 17/20 K.TRLEQEIATYR.R "sp|Q04695|K1C17_HUMAN,sp|P02533|K1C14_HUMAN,sp|P35900|K1C20_HUMAN,sp|P08779|K1C16_HUMAN,sp|P19012|K1C15_HUMAN,sp|P13646|K1C13_HUMAN,tr|A0A3B3IS58|A0A3B3IS58_HUMAN,tr|F5GWP8|F5GWP8_HUMAN,tr|K7ERE3|K7ERE3_HUMAN,tr|A8MT21|A8MT21_HUMAN" 10 1378.7205 999 84213 15205 2 1378.719322 690.3675 "Keratin, type I cytoskeletal 17 OS=Homo sapiens OX=9606 GN=KRT17 PE=1 SV=2" 5.81 2593.3 - 5.89E+06 - - - -0.8385 - 3.496 0.583 - 438.1 1 2 1 -0.0012 11 0 0 0 4.10E+08 0.00E+00 - - - 6.7326 1 221125_WJC_METTL3_EV_vs_WT_F06.15218.15218.3 3.95E-05 18/52 K.TIDLGAAAHYTGDK[136.11].A sp|Q14677|EPN4_HUMAN 1 1439.7136 1.61 84222 15218 3 1439.711339 480.9118 Clathrin interactor 1 OS=Homo sapiens OX=9606 GN=CLINT1 PE=1 SV=1 5.18 2594.5 - 2.32E+06 - - - -1.576 - 2.984 0.523 - 291.2 1 2 0 -0.0023 14 0 0 0 3.91E+08 2.43E+08 - - - 7.2757 0.9991 221125_WJC_METTL3_EV_vs_WT_F06.15224.15224.4 0.0586 20/84 K.LKEDISQGVHISVYR.V sp|O43395|PRPF3_HUMAN 1 1742.9315 0.7 84226 15224 4 1742.929168 436.7402 U4\U6 small nuclear ribonucleoprotein Prp3 OS=Homo sapiens OX=9606 GN=PRPF3 PE=1 SV=2 6.75 2595.2 - 2.09E+06 - - - -1.3575 - 3.162 0.358 - 430.3 1 2 1 -0.0024 15 0 0 0 9.68E+07 1.39E+08 - - - 2.7533 0.9998 221125_WJC_METTL3_EV_vs_WT_F06.15229.15229.3 3.32E-09 18/48 K.SKITVTSEVPFSK.R "sp|P35268|RL22_HUMAN,tr|K7EKS7|K7EKS7_HUMAN,tr|K7ERI7|K7ERI7_HUMAN,tr|K7EMH1|K7EMH1_HUMAN,tr|K7ELC4|K7ELC4_HUMAN,tr|K7EP65|K7EP65_HUMAN,tr|K7EJT5|K7EJT5_HUMAN" 7 1421.7766 0.71 84228 15229 3 1421.772284 474.9328 60S ribosomal protein L22 OS=Homo sapiens OX=9606 GN=RPL22 PE=1 SV=2 8.31 2595.9 - 2.83E+06 - - - -3.0328 - 3.148 0.564 - 485.9 1 2 1 -0.0043 13 0 0 0 8.06E+07 1.14E+08 - - - 7.9361 1 221125_WJC_METTL3_EV_vs_WT_F06.15231.15231.3 1.85E-06 18/52 K.TIDLGAAAHYTGDK.A sp|Q14677|EPN4_HUMAN 1 1431.6994 1.57 84229 15231 3 1431.696241 478.2404 Clathrin interactor 1 OS=Homo sapiens OX=9606 GN=CLINT1 PE=1 SV=1 5.18 2596.1 - 7.44E+06 - - - -2.2121 - 3.185 0.558 - 271.7 1 2 0 -0.0032 14 0 0 0 3.79E+08 2.42E+08 - - - 7.8389 1 221125_WJC_METTL3_EV_vs_WT_F06.15232.15232.3 3.92E-09 22/60 K.NQVAMNPTNTVFDAK[136.11]R[166.11].L "sp|P11142|HSP7C_HUMAN,tr|E9PQQ4|E9PQQ4_HUMAN,tr|E9PNE6|E9PNE6_HUMAN,tr|E9PKE3|E9PKE3_HUMAN,tr|E9PLF4|E9PLF4_HUMAN,tr|E9PK54|E9PK54_HUMAN,tr|E9PN25|E9PN25_HUMAN,tr|E9PPY6|E9PPY6_HUMAN,tr|E9PQK7|E9PQK7_HUMAN" 9 1822.9115 0.12 84230 15232 3 1822.906918 608.6444 Heat shock cognate 71 kDa protein OS=Homo sapiens OX=9606 GN=HSPA8 PE=1 SV=1 8.75 2596.3 - 2.76E+06 - - - -2.5064 - 2.98 0.585 - 444.7 1 2 0 -0.0046 16 0 0 0 4.80E+07 4.02E+08 - - - 7.8626 0.9844 221125_WJC_METTL3_EV_vs_WT_F06.15233.15233.2 7.27E-06 13/24 K.IELFGR[166.11]PHNVQPN.W sp|Q86U44|MTA70_HUMAN 1 1529.7978 0.001 84231 15233 2 1529.795134 765.9062 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 6.75 2596.4 - 1.64E+06 - - - -1.763 - 2.301 0.459 - 401.8 1 1 0 -0.0027 13 0 0 0 0.00E+00 1.32E+08 - - - 4.5691 0.8244 221125_WJC_METTL3_EV_vs_WT_F06.15244.15244.4 144 Feb-72 K.DWPC[160.03]NYDWDSDDD.A sp|Q9H213|MAGH1_HUMAN 1 1701.5525 - 84238 15244 4 1701.546393 426.3954 Melanoma-associated antigen H1 OS=Homo sapiens OX=9606 GN=MAGEH1 PE=1 SV=1 3.32 2597.6 - 3.26E+06 - - - -3.6161 - 0.523 0.43 - 2.1 2 1 0 -0.0062 13 0 0 0 - - - - - 2.4973 0.9898 221125_WJC_METTL3_EV_vs_WT_F06.15245.15245.2 5.26E-05 30-Oct R.TSTSTLLHTSVESEAN.L "sp|Q14157|UBP2L_HUMAN,tr|F8W726|F8W726_HUMAN,tr|H7C2T8|H7C2T8_HUMAN" 3 1675.7901 - 84239 15245 2 1675.787572 838.9023 Ubiquitin-associated protein 2-like OS=Homo sapiens OX=9606 GN=UBAP2L PE=1 SV=2 4.5 2597.7 - 1.02E+06 - - - -1.493 - 2.332 0.526 - 197.7 1 1 0 -0.0025 16 0 0 0 - - - - - 5.007 0.9996 221125_WJC_METTL3_EV_vs_WT_F06.15251.15251.3 1.73E-07 15/68 R.SPLLAGGSPPQPVVPAHK[136.11].D "sp|Q8NFH5|NUP35_HUMAN,tr|F8WCF5|F8WCF5_HUMAN,tr|F8WEL4|F8WEL4_HUMAN,tr|C9JIY9|C9JIY9_HUMAN,tr|C9IYQ7|C9IYQ7_HUMAN" 5 1758.9872 3.01 84242 15251 3 1758.996825 587.3363 Nucleoporin NUP35 OS=Homo sapiens OX=9606 GN=NUP35 PE=1 SV=1 8.49 2598.4 - 7.46E+06 - - - 5.4696 - 2.458 0.583 - 211.7 1 2 0 0.0096 18 0 0 0 5.39E+08 1.79E+08 - - - 7.2767 0.9999 221125_WJC_METTL3_EV_vs_WT_F06.15253.15253.2 1.07E-06 16/26 K.TIDLGAAAHYTGDK.A sp|Q14677|EPN4_HUMAN 1 1431.6994 2.11 84243 15253 2 1431.699769 716.857 Clathrin interactor 1 OS=Homo sapiens OX=9606 GN=CLINT1 PE=1 SV=1 5.18 2598.6 - 1.63E+06 - - - 0.2521 - 2.749 0.543 - 627.7 1 2 0 0.0004 14 0 0 0 4.37E+07 2.07E+07 - - - 5.5891 0.9271 221125_WJC_METTL3_EV_vs_WT_F06.15255.15255.3 4.32E-05 14/48 K.SFSVSSNLINHQR[166.11].L sp|Q9UEG4|ZN629_HUMAN 1 1497.7564 0.79 84244 15255 3 1497.749812 500.2594 Zinc finger protein 629 OS=Homo sapiens OX=9606 GN=ZNF629 PE=1 SV=2 9.49 2598.8 - 1.48E+06 - - - -4.3719 - 2.221 0.114 - 159.6 1 2 0 -0.0065 13 0 0 0 3.33E+07 4.25E+07 - - - 1.9727 1 221125_WJC_METTL3_EV_vs_WT_F06.15256.15256.3 2.58E-08 17/52 K.EMQDLSEFC[160.03]SDK[136.11]PK[136.11].S sp|Q96A33|CCD47_HUMAN 1 1728.767 1.91 84245 15256 3 1728.76694 577.2629 PAT complex subunit CCDC47 OS=Homo sapiens OX=9606 GN=CCDC47 PE=1 SV=1 4.32 2598.9 - 1.55E+06 - - - -0.0191 - 2.851 0.566 - 345.6 1 2 0 0 14 0 0 0 3.47E+07 1.82E+07 - - - 7.6345 1 221125_WJC_METTL3_EV_vs_WT_F06.15257.15257.3 5.41E-07 16/48 K.SFSVSSNLINHQR.L sp|Q9UEG4|ZN629_HUMAN 1 1487.7481 0.82 84246 15257 3 1487.74769 496.9233 Zinc finger protein 629 OS=Homo sapiens OX=9606 GN=ZNF629 PE=1 SV=2 9.49 2599 - 2.12E+06 - - - -0.2689 - 3.112 0.55 - 203.3 1 2 0 -0.0004 13 0 0 0 3.31E+07 4.05E+07 - - - 7.7499 1 221125_WJC_METTL3_EV_vs_WT_F06.15264.15264.3 1.96E-06 16/40 K.TKPHLFYIPGR.M sp|Q9H307|PININ_HUMAN 1 1327.7401 1.51 84251 15264 3 1327.738039 443.5873 Pinin OS=Homo sapiens OX=9606 GN=PNN PE=1 SV=5 9.99 2599.9 - 2.34E+06 - - - -1.5455 - 2.501 0.527 - 354.9 1 2 0 -0.0021 11 0 0 0 2.49E+08 1.65E+08 - - - 7.0191 1 221125_WJC_METTL3_EV_vs_WT_F06.15266.15266.3 5.43E-06 15/48 R.WEYDESYC[160.03]DAVKK.T sp|O75063|XYLK_HUMAN 1 1691.7137 1.37 84253 15266 3 1691.710144 564.9119 Glycosaminoglycan xylosylkinase OS=Homo sapiens OX=9606 GN=FAM20B PE=1 SV=1 4.32 2600.1 - 1.45E+06 - - - -2.1245 - 2.665 0.628 - 206.9 1 2 0 -0.0036 13 0 0 0 2.24E+07 1.63E+07 - - - 8.1982 1 221125_WJC_METTL3_EV_vs_WT_F06.15272.15272.3 2.71E-06 23/60 K.NQVAMNPTNTVFDAKR.L "sp|P11142|HSP7C_HUMAN,tr|E9PQQ4|E9PQQ4_HUMAN,tr|E9PNE6|E9PNE6_HUMAN,tr|E9PKE3|E9PKE3_HUMAN,tr|E9PLF4|E9PLF4_HUMAN,tr|E9PK54|E9PK54_HUMAN,tr|E9PN25|E9PN25_HUMAN,tr|E9PPY6|E9PPY6_HUMAN,tr|E9PQK7|E9PQK7_HUMAN" 9 1804.889 0.12 84257 15272 3 1804.889369 602.6369 Heat shock cognate 71 kDa protein OS=Homo sapiens OX=9606 GN=HSPA8 PE=1 SV=1 8.75 2600.8 - 2.15E+06 - - - 0.195 - 4.046 0.581 - 808.2 1 2 0 0.0004 16 0 0 0 4.80E+07 4.02E+08 - - - 8.6039 1 221125_WJC_METTL3_EV_vs_WT_F06.15273.15273.3 5.57E-05 15/56 R.NSAGQTLSAVQLHVK[136.11].E "sp|O75147|OBSL1_HUMAN,tr|A6NN50|A6NN50_HUMAN" 2 1559.8511 1.25 84258 15273 3 1559.850733 520.9576 Obscurin-like protein 1 OS=Homo sapiens OX=9606 GN=OBSL1 PE=1 SV=4 8.76 2601 - 1.83E+06 - - - -0.2385 - 2.883 0.478 - 320 1 2 0 -0.0004 15 0 0 0 2.75E+07 2.20E+07 - - - 6.632 0.9997 221125_WJC_METTL3_EV_vs_WT_F06.15274.15274.3 0.00957 Dec-48 K.SFDLIHSPHGELK.A sp|Q9UNX4|WDR3_HUMAN 1 1478.7518 0.87 84259 15274 3 1478.750894 493.9245 WD repeat-containing protein 3 OS=Homo sapiens OX=9606 GN=WDR3 PE=1 SV=1 5.94 2601.1 - 1.30E+06 - - - -0.5978 - 2.152 0.324 - 119.6 1 2 0 -0.0009 13 0 0 0 2.06E+07 2.37E+07 - - - 4.23 0.9999 221125_WJC_METTL3_EV_vs_WT_F06.15276.15276.3 1.13E-08 20/68 R.VK[136.11]LESPTVSTLTPSSPGK[136.11].L "sp|Q96C36|P5CR2_HUMAN,tr|A0A087WZR9|A0A087WZR9_HUMAN,tr|A0A087WTV6|A0A087WTV6_HUMAN" 3 1843.0273 0.78 84261 15276 3 1843.023745 615.3497 Pyrroline-5-carboxylate reductase 2 OS=Homo sapiens OX=9606 GN=PYCR2 PE=1 SV=1 8.56 2601.3 - 1.02E+06 - - - -1.9528 - 3.541 0.575 - 484.2 1 2 1 -0.0036 18 0 0 0 2.02E+07 2.59E+07 - - - 8.0982 1 221125_WJC_METTL3_EV_vs_WT_F06.15278.15278.2 3.01E-09 15/26 K.NQDEESQEAPELLK.R "sp|Q8NE71|ABCF1_HUMAN,tr|Q5STZ8|Q5STZ8_HUMAN,tr|H0YGW7|H0YGW7_HUMAN" 3 1628.753 1.14 84263 15278 2 1628.75414 815.3838 ATP-binding cassette sub-family F member 1 OS=Homo sapiens OX=9606 GN=ABCF1 PE=1 SV=2 3.91 2601.6 - 869268 - - - 0.7245 - 3.213 0.653 - 742.5 1 2 0 0.0012 14 0 0 0 4.21E+07 3.69E+07 - - - 6.7927 1 221125_WJC_METTL3_EV_vs_WT_F06.15283.15283.3 1.41E-05 18/40 K.TK[136.11]PHLFYIPGR[166.11].M sp|Q9H307|PININ_HUMAN 1 1345.7626 1.51 84266 15283 3 1345.761775 449.5948 Pinin OS=Homo sapiens OX=9606 GN=PNN PE=1 SV=5 9.99 2602.3 - 7.55E+06 - - - -0.5841 - 2.498 0.54 - 500.8 1 2 0 -0.0008 11 0 0 0 2.50E+08 1.65E+08 - - - 7.161 0.994 221125_WJC_METTL3_EV_vs_WT_F06.15286.15286.4 1.06E-06 16/78 N.QIPIISAEHLTSHK.Y "sp|Q9NR56|MBNL1_HUMAN,tr|Q86VM6|Q86VM6_HUMAN,tr|A0A0A0MQX8|A0A0A0MQX8_HUMAN" 3 1572.8624 1.74 84269 15286 4 1572.861703 394.2229 Muscleblind-like protein 1 OS=Homo sapiens OX=9606 GN=MBNL1 PE=1 SV=2 6.92 2602.6 - 912572 - - - -0.4374 - 2.762 0.464 - 272.2 1 1 0 -0.0007 14 0 0 0 2.62E+07 1.50E+07 - - - 3.6342 1 221125_WJC_METTL3_EV_vs_WT_F06.15291.15291.2 9.91E-10 15/26 K.NQDEESQEAPELLK[136.11].R "sp|Q8NE71|ABCF1_HUMAN,tr|Q5STZ8|Q5STZ8_HUMAN,tr|H0YGW7|H0YGW7_HUMAN" 3 1636.7672 1.14 84272 15291 2 1636.765855 819.3909 ATP-binding cassette sub-family F member 1 OS=Homo sapiens OX=9606 GN=ABCF1 PE=1 SV=2 3.91 2603.2 - 2.12E+06 - - - -0.7973 - 3.04 0.626 - 703.3 1 2 0 -0.0013 14 0 0 0 4.21E+07 3.69E+07 - - - 6.4544 0.9905 221125_WJC_METTL3_EV_vs_WT_F06.15292.15292.3 0.000225 19/56 Y.C[160.03]TLLASAQSEAEKER.L "sp|O75643|U520_HUMAN,tr|A0A494C1A5|A0A494C1A5_HUMAN" 2 1691.8148 1.76 84273 15292 3 1691.814368 564.9456 U5 small nuclear ribonucleoprotein 200 kDa helicase OS=Homo sapiens OX=9606 GN=SNRNP200 PE=1 SV=2 4.79 2603.3 - 1.10E+06 - - - -0.2843 - 3.517 0.471 - 554.4 1 1 1 -0.0005 15 0 0 0 1.61E+07 9.15E+06 - - - 7.0726 1 221125_WJC_METTL3_EV_vs_WT_F06.15294.15294.3 1.65E-05 Dec-44 R.FNIENIDGPHSK.V "sp|Q8N5I9|NOPC1_HUMAN,tr|A0A087WT30|A0A087WT30_HUMAN" 2 1369.6626 0.71 84275 15294 3 1369.662188 457.5615 NOP protein chaperone 1 OS=Homo sapiens OX=9606 GN=NOPCHAP1 PE=1 SV=2 5.32 2603.5 - 1.14E+06 - - - -0.322 - 2.33 0.475 - 118.3 1 2 0 -0.0004 12 0 0 0 1.15E+07 1.61E+07 - - - 6.1803 1 221125_WJC_METTL3_EV_vs_WT_F06.15295.15295.3 6.32E-09 19/60 R.AGDKDDITEPAVC[160.03]ALR.H sp|P14923|PLAK_HUMAN 1 1729.8305 42.68 84276 15295 3 1729.831339 577.6174 Junction plakoglobin OS=Homo sapiens OX=9606 GN=JUP PE=1 SV=3 4.23 2603.6 - 1.03E+06 - - - 0.4856 - 3.217 0.595 - 494.8 1 2 1 0.0008 16 0 0 0 3.92E+08 9.20E+06 - - - 8.1715 1 221125_WJC_METTL3_EV_vs_WT_F06.15296.15296.2 2.33E-10 14/30 K.NQVAMNPTNTVFDAK[136.11]R[166.11].L "sp|P11142|HSP7C_HUMAN,tr|E9PQQ4|E9PQQ4_HUMAN,tr|E9PNE6|E9PNE6_HUMAN,tr|E9PKE3|E9PKE3_HUMAN,tr|E9PLF4|E9PLF4_HUMAN,tr|E9PK54|E9PK54_HUMAN,tr|E9PN25|E9PN25_HUMAN,tr|E9PPY6|E9PPY6_HUMAN,tr|E9PQK7|E9PQK7_HUMAN" 9 1822.9115 0.03 84277 15296 2 1822.910293 912.463 Heat shock cognate 71 kDa protein OS=Homo sapiens OX=9606 GN=HSPA8 PE=1 SV=1 8.75 2603.8 - 466294 - - - -0.655 - 3.26 0.681 - 541.7 1 2 0 -0.0012 16 0 0 0 1.71E+05 6.19E+06 - - - 6.9758 0.9994 221125_WJC_METTL3_EV_vs_WT_F06.15306.15306.3 3.62E-06 Dec-40 K.IHIDLPNEQAR[166.11].L "sp|P62333|PRS10_HUMAN,tr|A0A087X2I1|A0A087X2I1_HUMAN" 2 1314.692 0.93 84285 15306 3 1314.692553 439.2379 26S proteasome regulatory subunit 10B OS=Homo sapiens OX=9606 GN=PSMC6 PE=1 SV=1 5.32 2604.8 - 604716 - - - 0.4442 - 2.44 0.231 - 289.6 1 2 0 0.0006 11 0 0 0 6.70E+06 7.20E+06 - - - 3.6493 1 221125_WJC_METTL3_EV_vs_WT_F06.15308.15308.4 4.85E-06 18/78 K.NPGVFLIHGPDEHR[166.11].H sp|O60476|MA1A2_HUMAN 1 1596.8036 1.42 84287 15308 4 1596.804099 400.2082 "Mannosyl-oligosaccharide 1,2-alpha-mannosidase IB OS=Homo sapiens OX=9606 GN=MAN1A2 PE=1 SV=1" 5.99 2605.1 - 579217 - - - 0.2849 - 3.181 0.509 - 379.7 1 2 0 0.0005 14 0 0 0 3.27E+07 2.31E+07 - - - 4.0774 0.8869 221125_WJC_METTL3_EV_vs_WT_F06.15309.15309.3 0.045 Dec-60 K.NQVAMNPTNTVFDAK[136.11]R.L "sp|P11142|HSP7C_HUMAN,tr|E9PQQ4|E9PQQ4_HUMAN,tr|E9PNE6|E9PNE6_HUMAN,tr|E9PKE3|E9PKE3_HUMAN,tr|E9PLF4|E9PLF4_HUMAN,tr|E9PK54|E9PK54_HUMAN,tr|E9PN25|E9PN25_HUMAN,tr|E9PPY6|E9PPY6_HUMAN,tr|E9PQK7|E9PQK7_HUMAN" 9 1812.9032 - 84288 15309 3 1813.90138 605.3083 Heat shock cognate 71 kDa protein OS=Homo sapiens OX=9606 GN=HSPA8 PE=1 SV=1 8.75 2605.2 - 525045 - - - 550.5881 - 2.254 0.249 - 99.6 1 2 0 0.9982 16 0 0 0 - - - - - 3.1249 0.9997 221125_WJC_METTL3_EV_vs_WT_F06.15310.15310.3 0.000628 Oct-48 R.TFSDISNFGAHQR.T "sp|Q5VV52|ZN691_HUMAN,tr|Q5VV50|Q5VV50_HUMAN,tr|A0A0A0MRR1|A0A0A0MRR1_HUMAN" 3 1478.6902 0.74 84289 15310 3 1478.691643 493.904 Zinc finger protein 691 OS=Homo sapiens OX=9606 GN=ZNF691 PE=1 SV=2 6.41 2605.3 - 464921 - - - 0.9481 - 1.778 0.376 - 78.2 1 2 0 0.0014 13 0 0 0 9.53E+06 1.30E+07 - - - 4.292 0.9281 221125_WJC_METTL3_EV_vs_WT_F06.15314.15314.2 4.58E-05 Aug-32 N.VTVSVTSSTISSNVASK.A sp|P35908|K22E_HUMAN 1 1665.8785 999 84293 15314 2 1665.88325 833.9465 "Keratin, type II cytoskeletal 2 epidermal OS=Homo sapiens OX=9606 GN=KRT2 PE=1 SV=2" 8.72 2605.8 - 182715 - - - 2.8543 - 1.842 0.405 - 54.7 1 1 0 0.0048 17 0 0 0 2.54E+06 0.00E+00 - - - 3.5326 0.9993 221125_WJC_METTL3_EV_vs_WT_F06.15319.15319.3 0.00078 15/44 K.FEKDQIIDSLKR.G "sp|Q6P3W7|SCYL2_HUMAN,tr|F8VSC5|F8VSC5_HUMAN,tr|A0A0U1RQQ9|A0A0U1RQQ9_HUMAN" 3 1490.8093 136.55 84296 15319 3 1490.810679 497.9437 SCY1-like protein 2 OS=Homo sapiens OX=9606 GN=SCYL2 PE=1 SV=1 6.12 2606.3 - 2.17E+06 - - - 0.9297 - 2.679 0.319 - 285.6 1 2 1 0.0014 12 0 0 0 1.70E+09 1.24E+07 - - - 4.8277 0.9999 221125_WJC_METTL3_EV_vs_WT_F06.15321.15321.4 0.000294 15/78 K.NPGVFLIHGPDEHR.H sp|O60476|MA1A2_HUMAN 1 1586.7954 1.21 84298 15321 4 1586.794917 397.7061 "Mannosyl-oligosaccharide 1,2-alpha-mannosidase IB OS=Homo sapiens OX=9606 GN=MAN1A2 PE=1 SV=1" 5.99 2606.5 - 1.47E+06 - - - -0.288 - 2.917 0.417 - 189.1 1 2 0 -0.0005 14 0 0 0 3.27E+07 2.69E+07 - - - 3.2451 0.9941 221125_WJC_METTL3_EV_vs_WT_F06.15323.15323.4 3.41 15/66 K.FEK[136.11]DQIIDSLK[136.11]R[166.11].G "sp|Q6P3W7|SCYL2_HUMAN,tr|F8VSC5|F8VSC5_HUMAN,tr|A0A0U1RQQ9|A0A0U1RQQ9_HUMAN" 3 1516.846 0.001 84300 15323 4 1516.846456 380.2188 SCY1-like protein 2 OS=Homo sapiens OX=9606 GN=SCYL2 PE=1 SV=1 6.12 2606.7 - 1.03E+06 - - - 0.325 - 2.556 0.265 - 123.1 1 2 1 0.0005 12 0 0 0 0.00E+00 6.97E+06 - - - 1.8876 0.8715 221125_WJC_METTL3_EV_vs_WT_F06.15324.15324.3 0.36 Oct-48 R.GLQTVHINENFAK[136.11].L "sp|Q13573|SNW1_HUMAN,tr|G3V4X8|G3V4X8_HUMAN,tr|G3V3A4|G3V3A4_HUMAN" 3 1477.7769 1.21 84301 15324 3 1477.777253 493.5996 SNW domain-containing protein 1 OS=Homo sapiens OX=9606 GN=SNW1 PE=1 SV=1 6.75 2606.8 - 755452 - - - 0.2544 - 1.755 0.033 - 83.4 2 2 0 0.0004 13 0 0 0 6.03E+06 4.99E+06 - - - 0.2935 1 221125_WJC_METTL3_EV_vs_WT_F06.15327.15327.2 5.98E-10 16/32 R.GNAGQSNYGFANSAMER.L "sp|P49327|FAS_HUMAN,tr|A0A0U1RQF0|A0A0U1RQF0_HUMAN" 2 1772.7536 3.19 84304 15327 2 1772.755436 887.3841 Fatty acid synthase OS=Homo sapiens OX=9606 GN=FASN PE=1 SV=3 6 2607.1 - 612257 - - - 1.0103 - 3.195 0.652 - 728.3 1 2 0 0.0018 17 0 0 0 6.24E+06 1.96E+06 - - - 6.7119 1 221125_WJC_METTL3_EV_vs_WT_F06.15328.15328.3 5.57E-10 17/60 R.DGTGHYLC[160.03]NAC[160.03]GLYSK.M sp|Q92908|GATA6_HUMAN 1 1814.7716 2.62 84305 15328 3 1814.771502 605.9311 Transcription factor GATA-6 OS=Homo sapiens OX=9606 GN=GATA6 PE=1 SV=2 6.72 2607.2 - 594916 - - - -0.0562 - 2.938 0.641 - 310.4 1 2 0 -0.0001 16 0 0 0 7.78E+06 2.97E+06 - - - 8.4518 0.8852 221125_WJC_METTL3_EV_vs_WT_F06.15329.15329.4 2.03 Aug-72 R.IC[160.03]VANTHLYWHPK.G "sp|Q6L8Q7|PDE12_HUMAN,tr|F6T1Q0|F6T1Q0_HUMAN" 2 1637.8137 0.55 84306 15329 4 1637.815992 410.4607 "2',5'-phosphodiesterase 12 OS=Homo sapiens OX=9606 GN=PDE12 PE=1 SV=2" 8.21 2607.4 - 401962 - - - 1.4196 - 1.38 0.118 - 40.7 1 2 0 0.0023 13 0 0 0 3.51E+06 6.44E+06 - - - 0.3718 0.9374 221125_WJC_METTL3_EV_vs_WT_F06.15334.15334.3 0.00106 Nov-56 Y.SEAVADREDDPNFFK.M "sp|P00367|DHE3_HUMAN,tr|A0A804HHS2|A0A804HHS2_HUMAN,tr|A0A804HKE0|A0A804HKE0_HUMAN,tr|A0A804HJZ0|A0A804HJZ0_HUMAN,tr|A0A804HJD7|A0A804HJD7_HUMAN" 5 1738.7798 2.47 84309 15334 3 1738.781234 580.6006 "Glutamate dehydrogenase 1, mitochondrial OS=Homo sapiens OX=9606 GN=GLUD1 PE=1 SV=2" 4.1 2608 - 1.96E+06 - - - 0.8 - 1.757 0.439 - 143 1 1 1 0.0014 15 0 0 0 1.65E+07 6.67E+06 - - - 4.9047 0.9993 221125_WJC_METTL3_EV_vs_WT_F06.15335.15335.3 0.00129 Dec-52 K.NPGVFLIHGPDEHR.H sp|O60476|MA1A2_HUMAN 1 1586.7954 0.76 84310 15335 3 1586.802684 529.9391 "Mannosyl-oligosaccharide 1,2-alpha-mannosidase IB OS=Homo sapiens OX=9606 GN=MAN1A2 PE=1 SV=1" 5.99 2608 - 3.25E+06 - - - 4.6068 - 2.404 0.435 - 194.1 1 2 0 0.0073 14 0 0 0 6.35E+07 8.41E+07 - - - 5.7188 1 221125_WJC_METTL3_EV_vs_WT_F06.15336.15336.3 1.98E-05 Dec-60 K.DALSSVQESQVAQQAR.G "sp|P02656|APOC3_HUMAN,tr|B0YIW2|B0YIW2_HUMAN" 2 1715.8438 7.91 84311 15336 3 1715.844541 572.9552 Apolipoprotein C-III OS=Homo sapiens OX=9606 GN=APOC3 PE=1 SV=1 4.37 2608.1 - 1.79E+06 - - - 0.408 - 3.028 0.465 - 191.8 1 2 0 0.0007 16 0 0 0 4.79E+07 6.05E+06 - - - 6.5668 1 221125_WJC_METTL3_EV_vs_WT_F06.15337.15337.3 2.50E-10 18/44 K.VHVGDEDFVHLR.V "sp|P04080|CYTB_HUMAN,tr|A0A1W2PQG6|A0A1W2PQG6_HUMAN" 2 1421.7052 0.24 84312 15337 3 1421.707677 474.909 Cystatin-B OS=Homo sapiens OX=9606 GN=CSTB PE=1 SV=2 5.21 2608.1 - 1.41E+06 - - - 1.769 - 3.176 0.57 - 604.8 1 2 0 0.0025 12 0 0 0 2.79E+07 1.14E+08 - - - 8.0975 0.9995 221125_WJC_METTL3_EV_vs_WT_F06.15338.15338.3 0.00379 13/64 K.SLYVAEYHSEPVEDEKP.- sp|P26196|DDX6_HUMAN 1 1990.916 1.41 84313 15338 3 1990.917981 664.6459 Probable ATP-dependent RNA helicase DDX6 OS=Homo sapiens OX=9606 GN=DDX6 PE=1 SV=2 4.25 2608.3 - 1.06E+06 - - - 0.9935 - 1.641 0.373 - 82 1 2 0 0.002 17 0 0 0 1.63E+07 1.16E+07 - - - 3.9493 0.8019 221125_WJC_METTL3_EV_vs_WT_F06.15340.15340.3 0.00566 Nov-56 Y.SEAVADR[166.11]EDDPNFFK[136.11].M "sp|P00367|DHE3_HUMAN,tr|A0A804HHS2|A0A804HHS2_HUMAN,tr|A0A804HKE0|A0A804HKE0_HUMAN,tr|A0A804HJZ0|A0A804HJZ0_HUMAN,tr|A0A804HJD7|A0A804HJD7_HUMAN" 5 1756.8023 263.35 84315 15340 3 1756.802548 586.608 "Glutamate dehydrogenase 1, mitochondrial OS=Homo sapiens OX=9606 GN=GLUD1 PE=1 SV=2" 4.1 2608.5 - 960946 - - - 0.1338 - 1.838 0.33 - 137.2 1 1 1 0.0002 15 0 0 0 4.90E+09 1.86E+07 - - - 3.8074 1 221125_WJC_METTL3_EV_vs_WT_F06.15345.15345.2 1.84E-06 18/30 K.DALSSVQESQVAQQAR.G "sp|P02656|APOC3_HUMAN,tr|B0YIW2|B0YIW2_HUMAN" 2 1715.8438 119 84320 15345 2 1715.845739 858.9292 Apolipoprotein C-III OS=Homo sapiens OX=9606 GN=APOC3 PE=1 SV=1 4.37 2609.1 - 473704 - - - 1.1062 - 3.893 0.66 - 1248.4 1 2 0 0.0019 16 0 0 0 1.89E+07 1.58E+05 - - - 7.2568 0.9994 221125_WJC_METTL3_EV_vs_WT_F06.15354.15354.3 0.000488 Nov-48 K.DVEEEKFPTQLSR.H sp|Q2TAY7|SMU1_HUMAN 1 1576.7733 0.78 84327 15354 3 1576.777157 526.5984 WD40 repeat-containing protein SMU1 OS=Homo sapiens OX=9606 GN=SMU1 PE=1 SV=2 4.41 2610.2 - 4.52E+06 - - - 2.4449 - 1.767 0.527 - 110 1 2 1 0.0039 13 0 0 0 6.32E+07 8.16E+07 - - - 5.958 0.9982 221125_WJC_METTL3_EV_vs_WT_F06.15355.15355.3 4.43E-07 14/56 A.SAVPELATDPELEK[136.11]K[136.11].L "sp|Q86U44|MTA70_HUMAN,tr|B4E349|B4E349_HUMAN,tr|F5H6D8|F5H6D8_HUMAN,tr|H0YFV6|H0YFV6_HUMAN,tr|B4DTN4|B4DTN4_HUMAN" 5 1641.8796 0.21 84328 15355 3 1641.878868 548.3005 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 4.41 2610.3 - 3.74E+06 - - - -0.4568 - 2.763 0.544 - 241.2 1 1 0 -0.0008 15 0 0 0 1.24E+07 5.95E+07 - - - 7.2568 0.9999 221125_WJC_METTL3_EV_vs_WT_F06.15356.15356.3 4.31E-07 15/56 R.ETGVDLTK[136.11]DNMALQR[166.11].V "sp|P38646|GRP75_HUMAN,tr|H0Y8K0|H0Y8K0_HUMAN,tr|A0A7I2V2G2|A0A7I2V2G2_HUMAN,tr|A0A7I2V3F7|A0A7I2V3F7_HUMAN,tr|A0A7I2YQB2|A0A7I2YQB2_HUMAN,tr|D6RCD7|D6RCD7_HUMAN" 6 1707.8581 0.45 84329 15356 3 1707.858259 570.2933 "Stress-70 protein, mitochondrial OS=Homo sapiens OX=9606 GN=HSPA9 PE=1 SV=2" 4.56 2610.3 - 9.95E+06 - - - 0.12 - 2.899 0.55 - 394.2 1 2 1 0.0002 15 0 0 0 8.29E+07 1.86E+08 - - - 7.4492 0.9998 221125_WJC_METTL3_EV_vs_WT_F06.15357.15357.3 3.63E-06 14/56 R.ETGVDLTKDNMALQR.V "sp|P38646|GRP75_HUMAN,tr|H0Y8K0|H0Y8K0_HUMAN,tr|A0A7I2V2G2|A0A7I2V2G2_HUMAN,tr|A0A7I2V3F7|A0A7I2V3F7_HUMAN,tr|A0A7I2YQB2|A0A7I2YQB2_HUMAN,tr|D6RCD7|D6RCD7_HUMAN" 6 1689.8356 0.61 84330 15357 3 1689.838139 564.2858 "Stress-70 protein, mitochondrial OS=Homo sapiens OX=9606 GN=HSPA9 PE=1 SV=2" 4.56 2610.3 - 2.29E+06 - - - 1.512 - 2.748 0.481 - 239.6 1 2 1 0.0026 15 0 0 0 1.11E+08 1.82E+08 - - - 6.5397 0.9999 221125_WJC_METTL3_EV_vs_WT_F06.15358.15358.3 8.43E-06 15/72 K.GFVPSPTSQPGGHESLVDR[166.11].W "sp|P26640|SYVC_HUMAN,tr|A0A140T936|A0A140T936_HUMAN" 2 1975.9627 1.37 84331 15358 3 1975.965604 659.6615 Valine--tRNA ligase OS=Homo sapiens OX=9606 GN=VARS1 PE=1 SV=4 5.32 2610.4 - 1.90E+06 - - - 1.4575 - 3.378 0.422 - 167.7 1 2 0 0.0029 19 0 0 0 3.56E+07 2.60E+07 - - - 6.2347 1 221125_WJC_METTL3_EV_vs_WT_F06.15361.15361.3 2.63E-08 19/72 K.GFVPSPTSQPGGHESLVDR.W "sp|P26640|SYVC_HUMAN,tr|A0A140T936|A0A140T936_HUMAN" 2 1965.9545 1.59 84334 15361 3 1965.955319 656.3254 Valine--tRNA ligase OS=Homo sapiens OX=9606 GN=VARS1 PE=1 SV=4 5.32 2610.7 - 1.13E+06 - - - 0.44 - 3.257 0.53 - 334.3 1 2 0 0.0009 19 0 0 0 4.16E+07 2.62E+07 - - - 7.3497 1 221125_WJC_METTL3_EV_vs_WT_F06.15363.15363.3 4.92E-06 14/76 R.GSSGVGLTAAVTTDQETGER[166.11].R "sp|P25205|MCM3_HUMAN,tr|J3KQ69|J3KQ69_HUMAN,tr|A0A499FHX9|A0A499FHX9_HUMAN" 3 1944.9264 0.55 84336 15363 3 1944.926013 649.3161 DNA replication licensing factor MCM3 OS=Homo sapiens OX=9606 GN=MCM3 PE=1 SV=3 4.14 2610.9 - 716529 - - - -0.198 - 2.744 0.512 - 148.3 1 2 0 -0.0004 20 0 0 0 1.91E+07 3.44E+07 - - - 6.6971 1 221125_WJC_METTL3_EV_vs_WT_F06.15365.15365.2 1.86E-07 17/30 R.AGDKDDITEPAVC[160.03]ALR.H sp|P14923|PLAK_HUMAN 1 1729.8305 36.74 84338 15365 2 1729.83012 865.9225 Junction plakoglobin OS=Homo sapiens OX=9606 GN=JUP PE=1 SV=3 4.23 2611.1 - 469497 - - - -0.2191 - 3.223 0.615 - 871.1 1 2 1 -0.0004 16 0 0 0 2.04E+07 5.56E+05 - - - 6.4605 1 221125_WJC_METTL3_EV_vs_WT_F06.15367.15367.2 2.38E-08 15/28 R.ETGVDLTK[136.11]DNMALQR[166.11].V "sp|P38646|GRP75_HUMAN,tr|H0Y8K0|H0Y8K0_HUMAN,tr|A0A7I2V2G2|A0A7I2V2G2_HUMAN,tr|A0A7I2V3F7|A0A7I2V3F7_HUMAN,tr|A0A7I2YQB2|A0A7I2YQB2_HUMAN,tr|D6RCD7|D6RCD7_HUMAN" 6 1707.8581 0.17 84340 15367 2 1707.849009 854.9363 "Stress-70 protein, mitochondrial OS=Homo sapiens OX=9606 GN=HSPA9 PE=1 SV=2" 4.56 2611.4 - 307524 - - - -5.2961 - 2.993 0.613 - 839.4 1 2 1 -0.009 15 0 0 0 9.71E+05 5.73E+06 - - - 6.261 1 221125_WJC_METTL3_EV_vs_WT_F06.15370.15370.3 4.47E-05 15/44 K.K[136.11]IHPQTIIAGWR[166.11].E "sp|P78371|TCPB_HUMAN,tr|F8VQ14|F8VQ14_HUMAN,tr|F5GWF6|F5GWF6_HUMAN" 3 1436.8371 0.47 84341 15370 3 1436.838033 479.953 T-complex protein 1 subunit beta OS=Homo sapiens OX=9606 GN=CCT2 PE=1 SV=4 11 2611.8 - 4.82E+06 - - - 0.6333 - 3.008 0.414 - 384.3 1 2 0 0.0009 12 0 0 0 1.40E+08 3.00E+08 - - - 6.208 1 221125_WJC_METTL3_EV_vs_WT_F06.15372.15372.2 1.22E-07 19/38 R.GSSGVGLTAAVTTDQETGER[166.11].R "sp|P25205|MCM3_HUMAN,tr|J3KQ69|J3KQ69_HUMAN,tr|A0A499FHX9|A0A499FHX9_HUMAN" 3 1944.9264 0.49 84343 15372 2 1944.926962 973.4705 DNA replication licensing factor MCM3 OS=Homo sapiens OX=9606 GN=MCM3 PE=1 SV=3 4.14 2612 - 1.00E+06 - - - 0.29 - 3.956 0.626 - 925.5 1 2 0 0.0006 20 0 0 0 1.48E+07 3.00E+07 - - - 7.0455 0.9921 221125_WJC_METTL3_EV_vs_WT_F06.15375.15375.3 0.0015 Sep-64 K.IDMSSNNGC[160.03]MRDPTLYR.C "sp|P07814|SYEP_HUMAN,tr|V9GYZ6|V9GYZ6_HUMAN" 2 2028.8816 1.08 84346 15375 3 2028.882657 677.3011 Bifunctional glutamate\proline--tRNA ligase OS=Homo sapiens OX=9606 GN=EPRS1 PE=1 SV=5 5.95 2612.4 - 460960 - - - 0.5382 - 2.068 0.229 - 99.1 1 2 1 0.0011 17 0 0 0 1.43E+07 1.32E+07 - - - 2.9284 1 221125_WJC_METTL3_EV_vs_WT_F06.15380.15380.2 1.66E-08 21/32 S.QELALTQSVGGDSSADR[166.11].L "sp|Q86U44|MTA70_HUMAN,tr|H0YFV6|H0YFV6_HUMAN" 2 1742.831 0.03 84349 15380 2 1742.829087 872.4228 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 4.03 2613 - 4.47E+06 - - - -1.1212 - 3.656 0.517 - 1904.1 1 1 0 -0.002 17 0 0 0 2.00E+06 7.65E+07 - - - 6.0461 1 221125_WJC_METTL3_EV_vs_WT_F06.15383.15383.3 0.000456 14/44 K.KIHPQTIIAGWR.E "sp|P78371|TCPB_HUMAN,tr|F8VQ14|F8VQ14_HUMAN,tr|F5GWF6|F5GWF6_HUMAN" 3 1418.8147 0.46 84352 15383 3 1418.814898 473.9455 T-complex protein 1 subunit beta OS=Homo sapiens OX=9606 GN=CCT2 PE=1 SV=4 11 2613.2 - 2.64E+06 - - - 0.1727 - 2.692 0.439 - 308.1 1 2 0 0.0002 12 0 0 0 1.40E+08 3.02E+08 - - - 6.1793 1 221125_WJC_METTL3_EV_vs_WT_F06.15384.15384.2 3.95E-08 16/26 K.SQIHDIVLVGGSTR[166.11].L "sp|P11142|HSP7C_HUMAN,tr|E9PNE6|E9PNE6_HUMAN,tr|A8K7Q2|A8K7Q2_HUMAN,tr|E9PKE3|E9PKE3_HUMAN,tr|E9PN89|E9PN89_HUMAN" 5 1490.8081 0.15 84353 15384 2 1490.808289 746.4113 Heat shock cognate 71 kDa protein OS=Homo sapiens OX=9606 GN=HSPA8 PE=1 SV=1 6.46 2613.4 - 743666 - - - 0.1529 - 2.916 0.655 - 890.2 1 2 0 0.0002 14 0 0 0 2.64E+07 1.80E+08 - - - 6.5644 1 221125_WJC_METTL3_EV_vs_WT_F06.15385.15385.2 2.00E-06 20/38 R.GSSGVGLTAAVTTDQETGER.R "sp|P25205|MCM3_HUMAN,tr|J3KQ69|J3KQ69_HUMAN,tr|A0A499FHX9|A0A499FHX9_HUMAN" 3 1934.9181 0.5 84354 15385 2 1934.919794 968.4663 DNA replication licensing factor MCM3 OS=Homo sapiens OX=9606 GN=MCM3 PE=1 SV=3 4.14 2613.5 - 586526 - - - 0.861 - 4.03 0.648 - 1136.5 1 2 0 0.0017 20 0 0 0 1.48E+07 2.98E+07 - - - 7.2532 0.9999 221125_WJC_METTL3_EV_vs_WT_F06.15389.15389.4 0.000362 15/84 R.FPPEASGYLHIGHAK.A "sp|P07814|SYEP_HUMAN,tr|V9GYZ6|V9GYZ6_HUMAN" 2 1622.8205 1.65 84358 15389 4 1622.82062 406.7124 Bifunctional glutamate\proline--tRNA ligase OS=Homo sapiens OX=9606 GN=EPRS1 PE=1 SV=5 6.92 2614 - 354569 - - - 0.0579 - 2.646 0.449 - 166.2 1 2 0 0.0001 15 0 0 0 5.87E+06 3.56E+06 - - - 3.4822 0.9998 221125_WJC_METTL3_EV_vs_WT_F06.15392.15392.3 7.83E-06 Oct-40 K.K[136.11]VPWFDQQNGR[166.11].T sp|Q92522|H1X_HUMAN 1 1391.7065 0.52 84360 15392 3 1391.706127 464.9094 Histone H1.10 OS=Homo sapiens OX=9606 GN=H1-10 PE=1 SV=1 8.75 2614.4 - 852363 - - - -0.2702 - 2.108 0.37 - 165.5 1 2 0 -0.0004 11 0 0 0 1.18E+07 2.26E+07 - - - 4.7835 0.9743 221125_WJC_METTL3_EV_vs_WT_F06.15394.15394.3 0.0429 13/40 E.SLKEELAYLKK.N sp|P02533|K1C14_HUMAN 1 1320.7653 999 84361 15394 3 1320.764529 441.2624 "Keratin, type I cytoskeletal 14 OS=Homo sapiens OX=9606 GN=KRT14 PE=1 SV=4" 8.16 2614.6 - 3.32E+06 - - - -0.586 - 2.679 0.401 - 185.2 1 1 1 -0.0008 11 0 0 0 6.22E+07 0.00E+00 - - - 5.81 1 221125_WJC_METTL3_EV_vs_WT_F06.15397.15397.3 6.88E-06 13/76 R.GSSGVGLTAAVTTDQETGER.R "sp|P25205|MCM3_HUMAN,tr|J3KQ69|J3KQ69_HUMAN,tr|A0A499FHX9|A0A499FHX9_HUMAN" 3 1934.9181 0.55 84364 15397 3 1934.917202 645.98 DNA replication licensing factor MCM3 OS=Homo sapiens OX=9606 GN=MCM3 PE=1 SV=3 4.14 2614.8 - 1.11E+06 - - - -0.4786 - 2.524 0.491 - 218.5 1 2 0 -0.0009 20 0 0 0 1.92E+07 3.47E+07 - - - 6.26 0.9988 221125_WJC_METTL3_EV_vs_WT_F06.15399.15399.4 0.00577 14/72 K.RTGQPMIHIYLDK.E "sp|Q01844|EWS_HUMAN,tr|B0QYK0|B0QYK0_HUMAN,tr|H7BY36|H7BY36_HUMAN,tr|A0A0D9SFL3|A0A0D9SFL3_HUMAN,tr|C9JGE3|C9JGE3_HUMAN" 5 1570.829 0.73 84366 15399 4 1570.829403 393.7145 RNA-binding protein EWS OS=Homo sapiens OX=9606 GN=EWSR1 PE=1 SV=1 8.6 2615 - 1.02E+06 - - - 0.2674 - 2.461 0.277 - 193.3 1 2 0 0.0004 13 0 0 0 1.74E+07 2.40E+07 - - - 1.9708 1 221125_WJC_METTL3_EV_vs_WT_F06.15406.15406.3 4.08E-07 Dec-44 R.SHSVFSVTIHMK.E "sp|P52732|KIF11_HUMAN,tr|A0A7I2YQY4|A0A7I2YQY4_HUMAN,tr|A0A7I2V3A9|A0A7I2V3A9_HUMAN,tr|A0A7I2V3V3|A0A7I2V3V3_HUMAN" 4 1371.6969 4.13 84371 15406 3 1371.695141 458.2396 Kinesin-like protein KIF11 OS=Homo sapiens OX=9606 GN=KIF11 PE=1 SV=2 8.51 2615.9 - 3.87E+06 - - - -1.2867 - 2.487 0.494 - 215 1 2 0 -0.0018 12 0 0 0 1.50E+08 3.63E+07 - - - 6.5725 1 221125_WJC_METTL3_EV_vs_WT_F06.15407.15407.3 3.77E-06 15/56 R.HSNVVILTTSNITEK[136.11].L sp|Q15645|PCH2_HUMAN 1 1662.9032 0.67 84372 15407 3 1662.903153 555.3083 Pachytene checkpoint protein 2 homolog OS=Homo sapiens OX=9606 GN=TRIP13 PE=1 SV=2 6.75 2615.9 - 1.83E+06 - - - -0.0283 - 2.765 0.521 - 394.2 1 2 0 0 15 0 0 0 1.89E+07 2.81E+07 - - - 7.0025 0.9999 221125_WJC_METTL3_EV_vs_WT_F06.15408.15408.3 1.79E-06 20/56 K.IAQLEEQLDNETK[136.11]ER[166.11].Q sp|P35579|MYH9_HUMAN 1 1832.9235 1.03 84373 15408 3 1832.924945 611.9818 Myosin-9 OS=Homo sapiens OX=9606 GN=MYH9 PE=1 SV=4 4.25 2616 - 1.56E+06 - - - 0.7933 - 3.457 0.432 - 721.6 1 2 1 0.0015 15 0 0 0 4.77E+07 4.63E+07 - - - 6.5926 1 221125_WJC_METTL3_EV_vs_WT_F06.15409.15409.3 5.14E-10 19/48 R.HTGYVIELQHVVK[136.11].G "sp|P47897|SYQ_HUMAN,tr|B4DDN1|B4DDN1_HUMAN,tr|H7C0R3|H7C0R3_HUMAN,tr|A0A0U1RQX5|A0A0U1RQX5_HUMAN,tr|A0A1B0GVU9|A0A1B0GVU9_HUMAN,tr|A0A0U1RQX9|A0A0U1RQX9_HUMAN,tr|A0A0U1RRC8|A0A0U1RRC8_HUMAN" 7 1529.8446 1.05 84374 15409 3 1529.84632 510.9555 Glutamine--tRNA ligase OS=Homo sapiens OX=9606 GN=QARS1 PE=1 SV=1 6.92 2616.1 - 851611 - - - 1.1485 - 3.365 0.58 - 484.3 1 2 0 0.0018 13 0 0 0 7.39E+07 7.04E+07 - - - 8.2959 0.9994 221125_WJC_METTL3_EV_vs_WT_F06.15411.15411.2 0.00556 22-Oct K.K[136.11]IHPQTIIAGWR[166.11].E "sp|P78371|TCPB_HUMAN,tr|F8VQ14|F8VQ14_HUMAN,tr|F5GWF6|F5GWF6_HUMAN" 3 1436.8371 0.38 84376 15411 2 1436.836662 719.4258 T-complex protein 1 subunit beta OS=Homo sapiens OX=9606 GN=CCT2 PE=1 SV=4 11 2616.4 - 539693 - - - -0.3208 - 1.724 0.314 - 231 1 2 0 -0.0005 12 0 0 0 5.58E+06 1.49E+07 - - - 2.7931 0.9988 221125_WJC_METTL3_EV_vs_WT_F06.15412.15412.3 0.000277 Nov-64 K.VK[136.11]EPSVQEATSTSDILK[136.11].V "sp|Q8IYB3|SRRM1_HUMAN,tr|M0R088|M0R088_HUMAN,tr|E9PCT1|E9PCT1_HUMAN,tr|A9Z1X7|A9Z1X7_HUMAN" 4 1846.9859 0.76 84377 15412 3 1846.989831 616.6692 Serine\arginine repetitive matrix protein 1 OS=Homo sapiens OX=9606 GN=SRRM1 PE=1 SV=2 4.68 2616.5 - 524409 - - - 2.1424 - 2.187 0.403 - 93.2 1 2 1 0.004 17 0 0 0 8.58E+06 1.14E+07 - - - 5.0089 0.9999 221125_WJC_METTL3_EV_vs_WT_F06.15415.15415.2 1.33E-05 13/24 R.SQQQDDIEELETK.A "sp|Q9H4A3|WNK1_HUMAN,tr|F5GWT4|F5GWT4_HUMAN,tr|F6UYG0|F6UYG0_HUMAN" 3 1561.7108 1.85 84378 15415 2 1561.708611 781.8627 Serine\threonine-protein kinase WNK1 OS=Homo sapiens OX=9606 GN=WNK1 PE=1 SV=2 3.83 2616.9 - 1.77E+06 - - - -1.3767 - 2.671 0.55 - 573.3 1 2 0 -0.0022 13 0 0 0 7.90E+07 4.27E+07 - - - 5.6241 1 221125_WJC_METTL3_EV_vs_WT_F06.15416.15416.3 4.37E-10 17/48 R.HTGYVIELQHVVK.G "sp|P47897|SYQ_HUMAN,tr|B4DDN1|B4DDN1_HUMAN,tr|H7C0R3|H7C0R3_HUMAN,tr|A0A0U1RQX5|A0A0U1RQX5_HUMAN,tr|A0A1B0GVU9|A0A1B0GVU9_HUMAN,tr|A0A0U1RQX9|A0A0U1RQX9_HUMAN,tr|A0A0U1RRC8|A0A0U1RRC8_HUMAN" 7 1521.8304 1.05 84379 15416 3 1521.830591 508.2841 Glutamine--tRNA ligase OS=Homo sapiens OX=9606 GN=QARS1 PE=1 SV=1 6.92 2617 - 1.66E+06 - - - 0.1498 - 3.234 0.596 - 361.7 1 2 0 0.0002 13 0 0 0 7.36E+07 7.01E+07 - - - 8.367 0.9998 221125_WJC_METTL3_EV_vs_WT_F06.15417.15417.3 0.105 Nov-64 R.NQELSQSVSSTTR[166.11]PLLR[166.11].Q "sp|P82094|TMF1_HUMAN,tr|A0A2R8Y7M0|A0A2R8Y7M0_HUMAN" 2 1935.0288 1.62 84380 15417 3 1935.028177 646.0169 TATA element modulatory factor OS=Homo sapiens OX=9606 GN=TMF1 PE=1 SV=2 9.6 2617.1 - 2.46E+06 - - - -0.3442 - 2.459 0.332 - 157.2 1 2 0 -0.0007 17 0 0 0 2.24E+08 1.38E+08 - - - 4.5143 0.9902 221125_WJC_METTL3_EV_vs_WT_F06.15418.15418.4 0.00104 15/108 S.SMAEVDAAMAAR[166.11]PHSIDGR[166.11].V "sp|P22626|ROA2_HUMAN,tr|A0A7I2YQN4|A0A7I2YQN4_HUMAN,tr|A0A7I2V4N0|A0A7I2V4N0_HUMAN,tr|A0A024RA28|A0A024RA28_HUMAN,tr|A0A7I2V4N1|A0A7I2V4N1_HUMAN,tr|A0A7I2V4I6|A0A7I2V4I6_HUMAN,tr|A0A087WUI2|A0A087WUI2_HUMAN,tr|A0A7I2V4S4|A0A7I2V4S4_HUMAN,tr|A0A7I2V323|A0A7I2V323_HUMAN,tr|A0A7I2V3P1|A0A7I2V3P1_HUMAN,tr|A0A7I2V3P7|A0A7I2V3P7_HUMAN" 11 2003.942 1.37 84381 15418 4 2003.940812 501.9928 Heterogeneous nuclear ribonucleoproteins A2\B1 OS=Homo sapiens OX=9606 GN=HNRNPA2B1 PE=1 SV=2 5.36 2617.2 - 1.11E+06 - - - -0.6023 - 2.768 0.43 - 151.2 1 1 0 -0.0012 19 0 0 0 2.74E+07 2.00E+07 - - - 3.3128 1 221125_WJC_METTL3_EV_vs_WT_F06.15419.15419.2 2.87E-09 13/24 R.SQQQDDIEELETK[136.11].A "sp|Q9H4A3|WNK1_HUMAN,tr|F5GWT4|F5GWT4_HUMAN,tr|F6UYG0|F6UYG0_HUMAN" 3 1569.725 1.85 84382 15419 2 1569.71932 785.8698 Serine\threonine-protein kinase WNK1 OS=Homo sapiens OX=9606 GN=WNK1 PE=1 SV=2 3.83 2617.3 - 1.01E+06 - - - -3.5936 - 2.668 0.649 - 449.2 1 2 0 -0.0056 13 0 0 0 7.90E+07 4.27E+07 - - - 6.3514 0.9493 221125_WJC_METTL3_EV_vs_WT_F06.15422.15422.3 0.285 Aug-44 K.EKFENLGIQPPK.G "sp|P17980|PRS6A_HUMAN,tr|R4GNH3|R4GNH3_HUMAN,tr|E9PMD8|E9PMD8_HUMAN,tr|E9PKD5|E9PKD5_HUMAN,tr|E9PM69|E9PM69_HUMAN,tr|E9PN50|E9PN50_HUMAN" 6 1398.7507 0.74 84385 15422 3 1398.751 467.2575 26S proteasome regulatory subunit 6A OS=Homo sapiens OX=9606 GN=PSMC3 PE=1 SV=3 6.24 2617.6 - 378218 - - - 0.203 - 1.344 0.212 - 77.4 1 2 1 0.0003 12 0 0 0 3.06E+07 4.15E+07 - - - 1.723 1 221125_WJC_METTL3_EV_vs_WT_F06.15426.15426.3 0.00178 19/60 R.KADTALASIPPVAEGK.A sp|Q01804|OTUD4_HUMAN 1 1566.8617 1.54 84387 15426 3 1566.86189 523.2945 OTU domain-containing protein 4 OS=Homo sapiens OX=9606 GN=OTUD4 PE=1 SV=4 6.07 2618.1 - 2.46E+06 - - - 0.1066 - 3.228 0.443 - 510.1 1 2 0 0.0002 16 0 0 0 9.01E+07 5.83E+07 - - - 6.4858 0.9385 221125_WJC_METTL3_EV_vs_WT_F06.15427.15427.2 0.0362 12-Aug F.SVTIHMK.E "sp|P52732|KIF11_HUMAN,tr|A0A7I2YQY4|A0A7I2YQY4_HUMAN,tr|A0A7I2V3A9|A0A7I2V3A9_HUMAN,tr|A0A7I2V3V3|A0A7I2V3V3_HUMAN" 4 814.4371 3.96 84388 15427 2 814.436418 408.2258 Kinesin-like protein KIF11 OS=Homo sapiens OX=9606 GN=KIF11 PE=1 SV=2 8.49 2618.3 - 1.88E+06 - - - -0.8484 - 1.208 0.374 - 179.9 1 1 0 -0.0007 7 0 0 0 3.36E+07 8.49E+06 - - - 2.4019 0.9798 221125_WJC_METTL3_EV_vs_WT_F06.15433.15433.4 0.26 Nov-72 R.HTGYVIELQHVVK[136.11].G "sp|P47897|SYQ_HUMAN,tr|B4DDN1|B4DDN1_HUMAN,tr|H7C0R3|H7C0R3_HUMAN,tr|A0A0U1RQX5|A0A0U1RQX5_HUMAN,tr|A0A1B0GVU9|A0A1B0GVU9_HUMAN,tr|A0A0U1RQX9|A0A0U1RQX9_HUMAN,tr|A0A0U1RRC8|A0A0U1RRC8_HUMAN" 7 1529.8446 0.84 84394 15433 4 1529.84278 383.4684 Glutamine--tRNA ligase OS=Homo sapiens OX=9606 GN=QARS1 PE=1 SV=1 6.92 2618.9 - 507713 - - - -1.1655 - 1.81 0.17 - 87.6 1 2 0 -0.0018 13 0 0 0 5.99E+06 7.14E+06 - - - 0.9252 1 221125_WJC_METTL3_EV_vs_WT_F06.15434.15434.2 8.90E-10 22-Dec R.SHSVFSVTIHMK.E "sp|P52732|KIF11_HUMAN,tr|A0A7I2YQY4|A0A7I2YQY4_HUMAN,tr|A0A7I2V3A9|A0A7I2V3A9_HUMAN,tr|A0A7I2V3V3|A0A7I2V3V3_HUMAN" 4 1371.6969 17.54 84395 15434 2 1371.7001 686.8557 Kinesin-like protein KIF11 OS=Homo sapiens OX=9606 GN=KIF11 PE=1 SV=2 8.51 2619 - 382259 - - - 2.3285 - 2.501 0.637 - 418.9 1 2 0 0.0032 12 0 0 0 6.54E+06 3.73E+05 - - - 6.1568 1 221125_WJC_METTL3_EV_vs_WT_F06.15439.15439.3 4.30E-12 23/68 K.LGEMWNNTAADDK[136.11]QPYEK[136.11].K "sp|P09429|HMGB1_HUMAN,tr|Q5T7C4|Q5T7C4_HUMAN" 2 2124.9757 0.16 84398 15439 3 2124.97295 709.3325 High mobility group protein B1 OS=Homo sapiens OX=9606 GN=HMGB1 PE=1 SV=3 4.32 2619.5 - 4.72E+06 - - - -1.3035 - 4.427 0.605 - 611.1 1 2 1 -0.0028 18 0 0 0 1.57E+07 9.74E+07 - - - 8.989 1 221125_WJC_METTL3_EV_vs_WT_F06.15441.15441.3 1.81E-09 16/60 R.RGDALIEMESEQDVQK.A "sp|Q12849|GRSF1_HUMAN,tr|H0YAK1|H0YAK1_HUMAN,tr|H0Y8R1|H0Y8R1_HUMAN,tr|F5H5I6|F5H5I6_HUMAN,tr|H0YAM1|H0YAM1_HUMAN" 5 1846.8731 1.44 84400 15441 3 1846.87372 616.6316 G-rich sequence factor 1 OS=Homo sapiens OX=9606 GN=GRSF1 PE=1 SV=3 4.18 2619.7 - 986193 - - - 0.34 - 3.547 0.566 - 440.4 1 2 0 0.0006 16 0 0 0 3.43E+07 2.38E+07 - - - 8.0988 0.9575 221125_WJC_METTL3_EV_vs_WT_F06.15442.15442.3 0.0793 13/52 R.QNELR[166.11]QEMLDDVQK[136.11].K "sp|Q15643|TRIPB_HUMAN,tr|H0YJ97|H0YJ97_HUMAN" 2 1762.8639 1.86 84401 15442 3 1762.867811 588.6286 Thyroid receptor-interacting protein 11 OS=Homo sapiens OX=9606 GN=TRIP11 PE=1 SV=3 4.32 2619.8 - 906316 - - - 2.2367 - 1.859 0.193 - 135.5 1 2 1 0.0039 14 0 0 0 2.79E+07 1.50E+07 - - - 2.3384 0.9997 221125_WJC_METTL3_EV_vs_WT_F06.15445.15445.4 0.00666 Dec-66 K.DSEKEFHVLPYR.V sp|Q5SWX8|ODR4_HUMAN 1 1518.7467 1.15 84404 15445 4 1518.746416 380.6939 Protein odr-4 homolog OS=Homo sapiens OX=9606 GN=ODR4 PE=1 SV=1 5.45 2620.2 - 642161 - - - -0.1824 - 2.402 0.445 - 141.8 1 2 1 -0.0003 12 0 0 0 1.43E+07 1.25E+07 - - - 3.4308 0.9987 221125_WJC_METTL3_EV_vs_WT_F06.15446.15446.3 1.31E-08 19/60 W.AYQHELEETTVPEIQR[166.11].T "sp|O60231|DHX16_HUMAN,tr|Q5SQH5|Q5SQH5_HUMAN,tr|A0A140T8Y5|A0A140T8Y5_HUMAN" 3 1951.9515 1.68 84405 15446 3 1951.950193 651.6578 Pre-mRNA-splicing factor ATP-dependent RNA helicase DHX16 OS=Homo sapiens OX=9606 GN=DHX16 PE=1 SV=2 4.48 2620.3 - 280379 - - - -0.6645 - 3.187 0.564 - 341.4 1 1 0 -0.0013 16 0 0 0 1.02E+07 6.09E+06 - - - 7.8017 0.8102 221125_WJC_METTL3_EV_vs_WT_F06.15449.15449.3 0.132 Dec-76 R.TVPGATTTSSAATETMENVK.K sp|O00268|TAF4_HUMAN 1 1994.9467 1.02 84406 15449 3 1994.954578 665.9895 Transcription initiation factor TFIID subunit 4 OS=Homo sapiens OX=9606 GN=TAF4 PE=1 SV=2 4.53 2620.7 - 850571 - - - 3.9735 - 2.034 0.082 - 106.4 1 2 0 0.0079 20 0 0 0 4.74E+06 4.66E+06 - - - 1.1745 1 221125_WJC_METTL3_EV_vs_WT_F06.15450.15450.3 3.47E-07 22/68 K.LGEMWNNTAADDKQPYEK.K "sp|P09429|HMGB1_HUMAN,tr|Q5T7C4|Q5T7C4_HUMAN" 2 2108.9473 0.16 84407 15450 3 2108.948803 703.9897 High mobility group protein B1 OS=Homo sapiens OX=9606 GN=HMGB1 PE=1 SV=3 4.32 2620.9 - 1.14E+06 - - - 0.7032 - 4.037 0.613 - 611.8 1 2 1 0.0015 18 0 0 0 1.57E+07 9.74E+07 - - - 8.8489 1 221125_WJC_METTL3_EV_vs_WT_F06.15452.15452.3 6.10E-07 17/60 R.R[166.11]GDALIEMESEQDVQK[136.11].A "sp|Q12849|GRSF1_HUMAN,tr|H0YAK1|H0YAK1_HUMAN,tr|H0Y8R1|H0Y8R1_HUMAN,tr|F5H5I6|F5H5I6_HUMAN,tr|H0YAM1|H0YAM1_HUMAN" 5 1864.8956 1.44 84409 15452 3 1864.895281 622.6391 G-rich sequence factor 1 OS=Homo sapiens OX=9606 GN=GRSF1 PE=1 SV=3 4.18 2621 - 1.36E+06 - - - -0.1507 - 3.679 0.523 - 410.2 1 2 0 -0.0003 16 0 0 0 3.42E+07 2.38E+07 - - - 7.7133 1 221125_WJC_METTL3_EV_vs_WT_F06.15453.15453.2 1.11E-09 Dec-38 R.TVPGATTTSSAATETMENVK.K sp|O00268|TAF4_HUMAN 1 1994.9467 32.03 84410 15453 2 1994.945262 998.4806 Transcription initiation factor TFIID subunit 4 OS=Homo sapiens OX=9606 GN=TAF4 PE=1 SV=2 4.53 2621.2 - 421244 - - - -0.6963 - 2.836 0.696 - 256.1 1 2 0 -0.0014 20 0 0 0 3.87E+06 1.21E+05 - - - 6.744 1 221125_WJC_METTL3_EV_vs_WT_F06.15457.15457.3 1.12E-05 13/44 R.SHSVFSVTIHMK[136.11].E "sp|P52732|KIF11_HUMAN,tr|A0A7I2YQY4|A0A7I2YQY4_HUMAN,tr|A0A7I2V3A9|A0A7I2V3A9_HUMAN,tr|A0A7I2V3V3|A0A7I2V3V3_HUMAN" 4 1379.7111 4.13 84412 15457 3 1379.711524 460.911 Kinesin-like protein KIF11 OS=Homo sapiens OX=9606 GN=KIF11 PE=1 SV=2 8.51 2621.6 - 2.15E+06 - - - 0.303 - 2.747 0.538 - 259.9 1 2 0 0.0004 12 0 0 0 1.50E+08 3.62E+07 - - - 7.339 0.8804 221125_WJC_METTL3_EV_vs_WT_F06.15458.15458.3 0.138 May-64 L.SALEQLEDGGC[160.03]YLC[160.03]SDK.K sp|Q8IWN7|RP1L1_HUMAN 1 1943.8241 999 84413 15458 3 1943.821342 648.9486 Retinitis pigmentosa 1-like 1 protein OS=Homo sapiens OX=9606 GN=RP1L1 PE=1 SV=5 3.92 2621.7 - 1.04E+06 - - - -1.4153 - 1.322 0.362 - 16.1 1 1 0 -0.0028 17 0 0 0 2.70E+07 0.00E+00 - - - 3.2804 0.9998 221125_WJC_METTL3_EV_vs_WT_F06.15461.15461.3 2.36E-06 17/56 K.SKVEDPEINSIQDIK.E "sp|Q14690|RRP5_HUMAN,tr|A0A3B3IUD7|A0A3B3IUD7_HUMAN" 2 1713.8785 4.6 84416 15461 3 1713.881666 572.3001 Protein RRP5 homolog OS=Homo sapiens OX=9606 GN=PDCD11 PE=1 SV=3 4.32 2622 - 692684 - - - 1.8502 - 3.045 0.487 - 409.7 1 2 1 0.0032 15 0 0 0 2.17E+07 4.72E+06 - - - 6.8742 1 221125_WJC_METTL3_EV_vs_WT_F06.15462.15462.3 4.80E-05 20/68 R.QFDNLK[136.11]PSGGYITGDQAR[166.11].N "sp|Q9NZM3|ITSN2_HUMAN,tr|A0A087WVF7|A0A087WVF7_HUMAN,tr|F8W719|F8W719_HUMAN,tr|E7EPJ2|E7EPJ2_HUMAN" 4 1983.9769 4.31 84417 15462 3 1983.978024 662.3329 Intersectin-2 OS=Homo sapiens OX=9606 GN=ITSN2 PE=1 SV=3 5.96 2622.1 - 691671 - - - 0.5544 - 3.019 0.501 - 407.1 1 2 0 0.0011 18 0 0 0 3.15E+07 7.30E+06 - - - 6.8767 0.9907 221125_WJC_METTL3_EV_vs_WT_F06.15465.15465.3 0.0117 Nov-40 R.NLFIGHFHTPK.N "sp|Q15643|TRIPB_HUMAN,tr|H0YJ97|H0YJ97_HUMAN" 2 1309.6931 0.75 84420 15465 3 1309.692787 437.5717 Thyroid receptor-interacting protein 11 OS=Homo sapiens OX=9606 GN=TRIP11 PE=1 SV=3 8.76 2622.5 - 492778 - - - -0.2703 - 2.002 0.12 - 142.1 1 2 0 -0.0004 11 0 0 0 1.59E+07 2.11E+07 - - - 1.8497 0.9822 221125_WJC_METTL3_EV_vs_WT_F06.15468.15468.2 0.0434 May-32 R.NQELSQSVSSTTRPLLR.Q "sp|P82094|TMF1_HUMAN,tr|A0A2R8Y7M0|A0A2R8Y7M0_HUMAN" 2 1915.0123 2.59 84423 15468 2 1915.005476 958.5134 TATA element modulatory factor OS=Homo sapiens OX=9606 GN=TMF1 PE=1 SV=2 9.6 2622.9 - 207863 - - - -3.565 - 1.261 0.294 - 16.9 3 2 0 -0.0068 17 0 0 0 4.62E+06 1.79E+06 - - - 1.5674 0.9999 221125_WJC_METTL3_EV_vs_WT_F06.15472.15472.3 1.31E-06 16/40 R.LDHK[136.11]FDLMYAK[136.11].R "sp|Q9NY65|TBA8_HUMAN,sp|P0DPH7|TBA3C_HUMAN,sp|Q71U36|TBA1A_HUMAN,sp|P0DPH8|TBA3D_HUMAN,sp|A6NHL2|TBAL3_HUMAN,sp|P68366|TBA4A_HUMAN,sp|P68363|TBA1B_HUMAN,sp|Q9BQE3|TBA1C_HUMAN,tr|F5H5D3|F5H5D3_HUMAN,tr|C9J2C0|C9J2C0_HUMAN,tr|V9GZ17|V9GZ17_HUMAN,tr|A0A7P0T945|A0A7P0T945_HUMAN" 12 1395.7192 0.53 84425 15472 3 1395.722019 466.247 Tubulin alpha-8 chain OS=Homo sapiens OX=9606 GN=TUBA8 PE=1 SV=1 6.75 2623.5 - 1.31E+06 - - - 2.0498 - 3.211 0.515 - 405.8 1 2 1 0.0029 11 0 0 0 8.89E+06 1.69E+07 - - - 7.595 0.9995 221125_WJC_METTL3_EV_vs_WT_F06.15474.15474.3 0.00742 Dec-40 R.NLFIGHFHTPK[136.11].N "sp|Q15643|TRIPB_HUMAN,tr|H0YJ97|H0YJ97_HUMAN" 2 1317.7073 0.89 84427 15474 3 1317.704144 440.2431 Thyroid receptor-interacting protein 11 OS=Homo sapiens OX=9606 GN=TRIP11 PE=1 SV=3 8.76 2623.7 - 823392 - - - -2.4262 - 2.067 0.348 - 197 1 2 0 -0.0032 11 0 0 0 1.54E+07 1.73E+07 - - - 4.4817 0.9996 221125_WJC_METTL3_EV_vs_WT_F06.15476.15476.4 6.37E-08 18/78 K.ALEVIKPAHILQEK.E sp|Q14152|EIF3A_HUMAN 1 1587.9348 1.4 84429 15476 4 1587.935158 397.991 Eukaryotic translation initiation factor 3 subunit A OS=Homo sapiens OX=9606 GN=EIF3A PE=1 SV=1 6.8 2623.9 - 669182 - - - 0.2078 - 3.115 0.32 - 265.9 1 2 0 0.0003 14 0 0 0 2.99E+07 2.13E+07 - - - 2.4247 0.9999 221125_WJC_METTL3_EV_vs_WT_F06.15480.15480.3 2.47E-06 Dec-48 R.SASPYHGFTIVNR.L "sp|Q9NPI6|DCP1A_HUMAN,tr|A0A087WT55|A0A087WT55_HUMAN,tr|A0A087WXD0|A0A087WXD0_HUMAN,tr|A0A087WVE6|A0A087WVE6_HUMAN" 4 1447.7208 1.1 84433 15480 3 1447.721576 483.5809 mRNA-decapping enzyme 1A OS=Homo sapiens OX=9606 GN=DCP1A PE=1 SV=3 8.49 2624.4 - 413919 - - - 0.5277 - 2.89 0.394 - 195.3 1 2 0 0.0008 13 0 0 0 6.95E+06 6.34E+06 - - - 5.8099 0.9973 221125_WJC_METTL3_EV_vs_WT_F06.15485.15485.3 0.00666 Sep-60 K.DALAALETPGR[166.11]PSQQK[136.11].R "sp|Q92547|TOPB1_HUMAN,tr|A0A2R8YD63|A0A2R8YD63_HUMAN" 2 1698.902 1.48 84436 15485 3 1698.905034 567.3079 DNA topoisomerase 2-binding protein 1 OS=Homo sapiens OX=9606 GN=TOPBP1 PE=1 SV=3 6.07 2625 - 334455 - - - 1.8047 - 2.161 0.242 - 64.5 3 2 0 0.0031 16 0 0 0 1.47E+07 9.94E+06 - - - 2.9936 0.9999 221125_WJC_METTL3_EV_vs_WT_F06.15499.15499.3 8.20E-07 17/92 K.VIDGTSGATLQASALSAK[136.11]PGGQVK[136.11].C "sp|Q9NR09|BIRC6_HUMAN,tr|A0A3B3IUB9|A0A3B3IUB9_HUMAN" 2 2271.2405 0.71 84448 15499 3 2271.248941 758.0875 Baculoviral IAP repeat-containing protein 6 OS=Homo sapiens OX=9606 GN=BIRC6 PE=1 SV=2 8.56 2626.6 - 398417 - - - 3.7055 - 2.97 0.604 - 192.8 1 2 0 0.0084 24 0 0 0 2.32E+06 3.25E+06 - - - 7.8 0.9973 221125_WJC_METTL3_EV_vs_WT_F06.15500.15500.4 0.000933 Dec-72 R.FIQFEPEEDIKRK.F "sp|Q9NUQ7|UFSP2_HUMAN,tr|D6RA67|D6RA67_HUMAN,tr|D6RB53|D6RB53_HUMAN,tr|D6RGX2|D6RGX2_HUMAN" 4 1677.8726 0.88 84449 15500 4 1677.875251 420.4754 Ufm1-specific protease 2 OS=Homo sapiens OX=9606 GN=UFSP2 PE=1 SV=3 4.87 2626.8 - 296201 - - - 1.5669 - 1.889 0.326 - 97.1 1 2 1 0.0026 13 0 0 0 2.85E+06 3.24E+06 - - - 2.2986 0.9943 221125_WJC_METTL3_EV_vs_WT_F06.15505.15505.3 0.00385 Nov-44 K.EK[136.11]FENLGIQPPK[136.11].G "sp|P17980|PRS6A_HUMAN,tr|R4GNH3|R4GNH3_HUMAN,tr|E9PMD8|E9PMD8_HUMAN,tr|E9PKD5|E9PKD5_HUMAN,tr|E9PM69|E9PM69_HUMAN,tr|E9PN50|E9PN50_HUMAN" 6 1414.7791 0.77 84453 15505 3 1414.779144 472.6003 26S proteasome regulatory subunit 6A OS=Homo sapiens OX=9606 GN=PSMC3 PE=1 SV=3 6.24 2627.2 - 1.39E+06 - - - 0.0198 - 1.593 0.298 - 160.9 1 2 1 0 12 0 0 0 3.32E+07 4.29E+07 - - - 3.153 0.9996 221125_WJC_METTL3_EV_vs_WT_F06.15507.15507.4 7.31E-06 19/84 K.MKEEVPTALVEAHVR.K "sp|Q8TAQ2|SMRC2_HUMAN,tr|F8VXC8|F8VXC8_HUMAN" 2 1707.8978 2.85 84455 15507 4 1707.898217 427.9817 SWI\SNF complex subunit SMARCC2 OS=Homo sapiens OX=9606 GN=SMARCC2 PE=1 SV=1 5.48 2627.4 - 1.10E+06 - - - 0.2494 - 3.814 0.404 - 402.1 1 2 1 0.0004 15 0 0 0 2.59E+07 9.08E+06 - - - 3.2213 1 221125_WJC_METTL3_EV_vs_WT_F06.15509.15509.2 1.58E-10 17/36 R.LLEGEDAHLSSQQASGQSY.S sp|P08779|K1C16_HUMAN 1 2018.9181 - 84457 15509 2 2018.916767 1010.4663 "Keratin, type I cytoskeletal 16 OS=Homo sapiens OX=9606 GN=KRT16 PE=1 SV=4" 4.13 2627.6 - 570588 - - - -0.6741 - 3.565 0.687 - 717.3 1 1 0 -0.0014 19 0 0 0 - - - - - 7.24 0.9997 221125_WJC_METTL3_EV_vs_WT_F06.15510.15510.4 0.000293 23/84 K.MK[136.11]EEVPTALVEAHVR[166.11].K "sp|Q8TAQ2|SMRC2_HUMAN,tr|F8VXC8|F8VXC8_HUMAN" 2 1725.9203 2.85 84458 15510 4 1725.916368 432.4873 SWI\SNF complex subunit SMARCC2 OS=Homo sapiens OX=9606 GN=SMARCC2 PE=1 SV=1 5.48 2627.8 - 475726 - - - -2.2556 - 4.142 0.458 - 533.8 1 2 1 -0.0039 15 0 0 0 2.59E+07 9.08E+06 - - - 3.7199 0.9999 221125_WJC_METTL3_EV_vs_WT_F06.15514.15514.3 0.0182 13/52 R.ANEHQGIGFLNDPR.R sp|Q92900|RENT1_HUMAN 1 1566.7539 1.18 84460 15514 3 1566.755856 523.2586 Regulator of nonsense transcripts 1 OS=Homo sapiens OX=9606 GN=UPF1 PE=1 SV=2 5.32 2628.2 - 2.98E+06 - - - 1.2465 - 2.276 0.392 - 143.6 1 2 0 0.002 14 0 0 0 7.76E+07 6.56E+07 - - - 5.0955 1 221125_WJC_METTL3_EV_vs_WT_F06.15518.15518.2 2.68E-13 19/32 K.VPEPC[160.03]PSIVTPAPAQQK.T sp|P22528|SPR1B_HUMAN 1 1817.9346 999 84464 15518 2 1817.936024 909.9746 Cornifin-B OS=Homo sapiens OX=9606 GN=SPRR1B PE=1 SV=2 5.97 2628.6 - 848708 - - - 0.7998 - 3.754 0.691 - 1087.9 1 2 0 0.0015 17 0 0 0 2.17E+07 0.00E+00 - - - 7.3965 0.9853 221125_WJC_METTL3_EV_vs_WT_F06.15520.15520.3 0.00954 Aug-40 R.EKDVSEYFYEK.S "sp|Q5VT06|CE350_HUMAN,tr|H0Y7F7|H0Y7F7_HUMAN,tr|Q5T2X4|Q5T2X4_HUMAN" 3 1435.6507 3.19 84466 15520 3 1435.652112 479.5575 Centrosome-associated protein 350 OS=Homo sapiens OX=9606 GN=CEP350 PE=1 SV=1 4.41 2628.9 - 725003 - - - 0.9647 - 1.501 0.258 - 81 1 2 1 0.0014 11 0 0 0 8.06E+06 2.53E+06 - - - 2.5698 0.9999 221125_WJC_METTL3_EV_vs_WT_F06.15528.15528.3 3.89E-08 21/56 K.MKEEVPTALVEAHVR.K "sp|Q8TAQ2|SMRC2_HUMAN,tr|F8VXC8|F8VXC8_HUMAN" 2 1707.8978 2.47 84472 15528 3 1707.899361 570.3065 SWI\SNF complex subunit SMARCC2 OS=Homo sapiens OX=9606 GN=SMARCC2 PE=1 SV=1 5.48 2629.9 - 2.07E+06 - - - 0.9193 - 3.424 0.566 - 664.1 1 2 1 0.0016 15 0 0 0 2.12E+07 8.59E+06 - - - 8.0615 0.96 221125_WJC_METTL3_EV_vs_WT_F06.15530.15530.3 0.00465 Sep-72 R.LLEGEDAHLSSQQASGQSY.S sp|P08779|K1C16_HUMAN 1 2018.9181 - 84474 15530 3 2018.918845 673.98 "Keratin, type I cytoskeletal 16 OS=Homo sapiens OX=9606 GN=KRT16 PE=1 SV=4" 4.13 2630 - 1.60E+06 - - - 0.3551 - 1.931 0.345 - 58.8 1 1 0 0.0007 19 0 0 0 - - - - - 4.0029 1 221125_WJC_METTL3_EV_vs_WT_F06.15531.15531.3 4.38E-07 15/68 K.YVHYEIDAC[160.03]MDSEAPGSK[136.11].D "sp|Q86U44|MTA70_HUMAN,tr|H0YFV6|H0YFV6_HUMAN" 2 2078.8805 0.02 84475 15531 3 2078.878847 693.9674 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 4.31 2630.1 - 1.59E+06 - - - -0.7913 - 2.906 0.555 - 201.5 1 2 0 -0.0016 18 0 0 0 1.80E+06 9.08E+07 - - - 7.3836 0.9999 221125_WJC_METTL3_EV_vs_WT_F06.15532.15532.3 0.000254 15/52 K.ALEVIKPAHILQEK.E sp|Q14152|EIF3A_HUMAN 1 1587.9348 1.33 84476 15532 3 1587.937237 530.3189 Eukaryotic translation initiation factor 3 subunit A OS=Homo sapiens OX=9606 GN=EIF3A PE=1 SV=1 6.8 2630.1 - 1.54E+06 - - - 1.5171 - 2.887 0.366 - 254 1 2 0 0.0024 14 0 0 0 2.84E+07 2.13E+07 - - - 5.4374 0.8913 221125_WJC_METTL3_EV_vs_WT_F06.15537.15537.3 0.000546 Oct-40 E.NLKEELAYLKK.N "sp|Q04695|K1C17_HUMAN,tr|K7EPJ9|K7EPJ9_HUMAN,tr|K7ESE1|K7ESE1_HUMAN,tr|F5GWP8|F5GWP8_HUMAN" 4 1347.7762 999 84481 15537 3 1347.778346 450.266 "Keratin, type I cytoskeletal 17 OS=Homo sapiens OX=9606 GN=KRT17 PE=1 SV=2" 8.43 2630.7 - 467898 - - - 1.5908 - 2.277 0.345 - 121 1 1 1 0.0021 11 0 0 0 4.32E+06 0.00E+00 - - - 4.7234 0.9999 221125_WJC_METTL3_EV_vs_WT_F06.15545.15545.3 6.14E-09 13/56 K.KLEEEQIILEDQNC[160.03]K.L sp|P35579|MYH9_HUMAN 1 1887.9248 1.12 84487 15545 3 1887.929754 630.3155 Myosin-9 OS=Homo sapiens OX=9606 GN=MYH9 PE=1 SV=4 4.25 2631.7 - 5.38E+06 - - - 2.6272 - 2.937 0.509 - 331.2 1 2 0 0.005 15 0 0 0 9.50E+07 8.51E+07 - - - 7.0248 0.9996 221125_WJC_METTL3_EV_vs_WT_F06.15547.15547.3 0.00172 14/40 R.LLASTLVHSVK.K "sp|Q9NYF8|BCLF1_HUMAN,tr|E9PKI6|E9PKI6_HUMAN,tr|A0A1W2PQ43|A0A1W2PQ43_HUMAN,tr|E9PK91|E9PK91_HUMAN,tr|E9PJA7|E9PJA7_HUMAN,tr|E9PK09|E9PK09_HUMAN,tr|E9PQN2|E9PQN2_HUMAN" 7 1166.7023 2.09 84489 15547 3 1166.702149 389.908 Bcl-2-associated transcription factor 1 OS=Homo sapiens OX=9606 GN=BCLAF1 PE=1 SV=2 8.76 2631.9 - 1.12E+06 - - - -0.1371 - 2.477 0.258 - 140.5 1 2 0 -0.0002 11 0 0 0 2.79E+07 1.33E+07 - - - 3.9932 0.9979 221125_WJC_METTL3_EV_vs_WT_F06.15548.15548.3 7.77E-11 17/76 H.FYTNPIAKPIPQTPESAGNK.H "sp|P52948|NUP98_HUMAN,tr|A0A3B3ITD8|A0A3B3ITD8_HUMAN" 2 2172.1215 2.35 84490 15548 3 2172.125352 725.0478 Nuclear pore complex protein Nup98-Nup96 OS=Homo sapiens OX=9606 GN=NUP98 PE=1 SV=4 8.5 2632 - 767880 - - - 1.7646 - 3.153 0.593 - 241.7 1 1 0 0.0038 20 0 0 0 6.31E+06 2.68E+06 - - - 7.9362 0.9999 221125_WJC_METTL3_EV_vs_WT_F06.15549.15549.3 0.00944 15/40 R.LLASTLVHSVK[136.11].K "sp|Q9NYF8|BCLF1_HUMAN,tr|E9PKI6|E9PKI6_HUMAN,tr|A0A1W2PQ43|A0A1W2PQ43_HUMAN,tr|E9PK91|E9PK91_HUMAN,tr|E9PJA7|E9PJA7_HUMAN,tr|E9PK09|E9PK09_HUMAN,tr|E9PQN2|E9PQN2_HUMAN" 7 1174.7165 2.09 84491 15549 3 1174.717866 392.5794 Bcl-2-associated transcription factor 1 OS=Homo sapiens OX=9606 GN=BCLAF1 PE=1 SV=2 8.76 2632.1 - 696415 - - - 1.1552 - 2.657 0.419 - 194 1 2 0 0.0014 11 0 0 0 2.79E+07 1.33E+07 - - - 5.9871 0.9892 221125_WJC_METTL3_EV_vs_WT_F06.15550.15550.3 0.029 Nov-60 R.LHTLEEEK[136.11]EELAQYQK[136.11].W sp|Q9UQE7|SMC3_HUMAN 1 2003.0182 0.39 84492 15550 3 2003.020749 668.68 Structural maintenance of chromosomes protein 3 OS=Homo sapiens OX=9606 GN=SMC3 PE=1 SV=2 4.64 2632.3 - 467013 - - - 1.2546 - 2.059 0.222 - 124.6 1 2 1 0.0025 16 0 0 0 1.89E+06 4.84E+06 - - - 2.8675 1 221125_WJC_METTL3_EV_vs_WT_F06.15554.15554.2 8.47E-12 19/28 K.KLEEEQIILEDQNC[160.03]K.L sp|P35579|MYH9_HUMAN 1 1887.9248 1.06 84496 15554 2 1887.925687 944.9697 Myosin-9 OS=Homo sapiens OX=9606 GN=MYH9 PE=1 SV=4 4.25 2632.8 - 279230 - - - 0.473 - 4.111 0.717 - 1424.7 1 2 0 0.0009 15 0 0 0 4.59E+06 4.34E+06 - - - 7.812 0.999 221125_WJC_METTL3_EV_vs_WT_F06.15557.15557.3 4.65E-06 13/44 K.DKNLPNVIINEK.R sp|Q9BVJ6|UT14A_HUMAN 1 1395.7722 2.11 84497 15557 3 1395.774322 466.2647 U3 small nucleolar RNA-associated protein 14 homolog A OS=Homo sapiens OX=9606 GN=UTP14A PE=1 SV=1 6.07 2633.2 - 1.68E+06 - - - 1.5354 - 2.529 0.333 - 363.8 1 2 1 0.0021 12 0 0 0 1.75E+07 8.28E+06 - - - 4.8238 1 221125_WJC_METTL3_EV_vs_WT_F06.15558.15558.3 1.49E-09 19/68 K.LLNTVEETTKDVSGLHSK.L "sp|P52732|KIF11_HUMAN,tr|A0A7I2YQY4|A0A7I2YQY4_HUMAN,tr|A0A7I2V3A9|A0A7I2V3A9_HUMAN" 3 1970.032 15.49 84498 15558 3 1970.038485 657.6846 Kinesin-like protein KIF11 OS=Homo sapiens OX=9606 GN=KIF11 PE=1 SV=2 5.45 2633.3 - 687365 - - - 3.2736 - 4.314 0.64 - 317.3 1 2 1 0.0065 18 0 0 0 9.11E+06 5.88E+05 - - - 9.3138 0.9992 221125_WJC_METTL3_EV_vs_WT_F06.15562.15562.2 0.0094 20-Sep R.LLASTLVHSVK[136.11].K "sp|Q9NYF8|BCLF1_HUMAN,tr|E9PKI6|E9PKI6_HUMAN,tr|A0A1W2PQ43|A0A1W2PQ43_HUMAN,tr|E9PK91|E9PK91_HUMAN,tr|E9PJA7|E9PJA7_HUMAN,tr|E9PK09|E9PK09_HUMAN,tr|E9PQN2|E9PQN2_HUMAN" 7 1174.7165 2.13 84502 15562 2 1174.717656 588.3655 Bcl-2-associated transcription factor 1 OS=Homo sapiens OX=9606 GN=BCLAF1 PE=1 SV=2 8.76 2633.8 - 577376 - - - 0.9764 - 1.864 0.28 - 165.9 1 2 0 0.0011 11 0 0 0 1.21E+07 5.67E+06 - - - 2.7933 0.999 221125_WJC_METTL3_EV_vs_WT_F06.15563.15563.3 0.000164 13/52 K.TGVHLPEPNLNSAR[166.11].R "sp|Q9H2Y7|ZN106_HUMAN,tr|H3BNX5|H3BNX5_HUMAN,tr|H3BSS6|H3BSS6_HUMAN" 3 1513.7877 1.71 84503 15563 3 1513.794219 505.6032 Zinc finger protein 106 OS=Homo sapiens OX=9606 GN=ZNF106 PE=1 SV=1 6.41 2634 - 454902 - - - 4.3328 - 2.18 0.41 - 168.8 1 2 0 0.0066 14 0 0 0 3.69E+07 2.15E+07 - - - 5.1804 1 221125_WJC_METTL3_EV_vs_WT_F06.15565.15565.2 2.34E-09 16/28 K.K[136.11]LEEEQIILEDQNC[160.03]K[136.11].L sp|P35579|MYH9_HUMAN 1 1903.9532 1.06 84505 15565 2 1903.94912 952.9839 Myosin-9 OS=Homo sapiens OX=9606 GN=MYH9 PE=1 SV=4 4.25 2634.2 - 355698 - - - -2.1398 - 3.909 0.626 - 1001.9 1 2 0 -0.0041 15 0 0 0 4.59E+06 4.34E+06 - - - 7.015 0.9996 221125_WJC_METTL3_EV_vs_WT_F06.15566.15566.3 1.99E-05 15/56 K.MK[136.11]EEVPTALVEAHVR[166.11].K "sp|Q8TAQ2|SMRC2_HUMAN,tr|F8VXC8|F8VXC8_HUMAN" 2 1725.9203 2.3 84506 15566 3 1725.920821 576.314 SWI\SNF complex subunit SMARCC2 OS=Homo sapiens OX=9606 GN=SMARCC2 PE=1 SV=1 5.48 2634.3 - 346338 - - - 0.3245 - 2.553 0.384 - 119.9 1 2 1 0.0006 15 0 0 0 2.01E+07 8.77E+06 - - - 5.2667 1 221125_WJC_METTL3_EV_vs_WT_F06.15572.15572.3 1.83E-07 14/60 K.AHLMEIQVNGGTVAEK[136.11].L "sp|P39023|RL3_HUMAN,tr|G5E9G0|G5E9G0_HUMAN,tr|H7C3M2|H7C3M2_HUMAN,tr|B5MCW2|B5MCW2_HUMAN,tr|H7C422|H7C422_HUMAN" 5 1703.8756 1.22 84510 15572 3 1703.880176 568.9658 60S ribosomal protein L3 OS=Homo sapiens OX=9606 GN=RPL3 PE=1 SV=2 5.4 2635 - 1.49E+06 - - - 2.6827 - 3.005 0.557 - 340.3 1 2 0 0.0046 16 0 0 0 3.59E+07 2.94E+07 - - - 7.5719 1 221125_WJC_METTL3_EV_vs_WT_F06.15573.15573.3 6.98E-07 16/52 K.TGVHLPEPNLNSAR.R "sp|Q9H2Y7|ZN106_HUMAN,tr|H3BNX5|H3BNX5_HUMAN,tr|H3BSS6|H3BSS6_HUMAN" 3 1503.7794 1.87 84511 15573 3 1503.780109 502.2671 Zinc finger protein 106 OS=Homo sapiens OX=9606 GN=ZNF106 PE=1 SV=1 6.41 2635.1 - 1.03E+06 - - - 0.4781 - 2.782 0.458 - 308.2 1 2 0 0.0007 14 0 0 0 1.23E+07 6.57E+06 - - - 6.3652 1 221125_WJC_METTL3_EV_vs_WT_F06.15574.15574.2 1.90E-11 16/28 Q.NSGDVNVEINVAPGK.D "sp|P35527|K1C9_HUMAN,tr|K7EQQ3|K7EQQ3_HUMAN" 2 1511.758 999 84512 15574 2 1511.759907 756.8863 "Keratin, type I cytoskeletal 9 OS=Homo sapiens OX=9606 GN=KRT9 PE=1 SV=3" 4.37 2635.2 - 2.19E+06 - - - 1.2707 - 3.575 0.675 - 617.8 1 1 0 0.0019 15 0 0 0 2.58E+07 0.00E+00 - - - 7.158 0.9421 221125_WJC_METTL3_EV_vs_WT_F06.15575.15575.4 0.126 16/96 T.YATVEEVDAAMNARPHK.V "sp|P09651|ROA1_HUMAN,tr|A0A7I2YQX9|A0A7I2YQX9_HUMAN,tr|A0A7I2V3W4|A0A7I2V3W4_HUMAN,tr|F8W646|F8W646_HUMAN,tr|F8VZ49|F8VZ49_HUMAN,tr|A0A7I2V3R8|A0A7I2V3R8_HUMAN,tr|F8W6I7|F8W6I7_HUMAN,tr|F8VYN5|F8VYN5_HUMAN,tr|A0A7I2V2L6|A0A7I2V2L6_HUMAN,tr|A0A7I2V3C7|A0A7I2V3C7_HUMAN,tr|A0A7I2V3W0|A0A7I2V3W0_HUMAN,tr|A0A7I2YQV3|A0A7I2YQV3_HUMAN,tr|A0A2R8Y4L2|A0A2R8Y4L2_HUMAN,tr|A0A7I2V2Z4|A0A7I2V2Z4_HUMAN,tr|A0A7I2V4M0|A0A7I2V4M0_HUMAN" 15 1900.9101 2.43 84513 15575 4 1900.913935 476.2348 Heterogeneous nuclear ribonucleoprotein A1 OS=Homo sapiens OX=9606 GN=HNRNPA1 PE=1 SV=5 5.45 2635.3 - 1.04E+06 - - - 1.9933 - 2.467 0.347 - 254.9 1 1 0 0.0038 17 0 0 0 2.19E+07 8.99E+06 - - - 2.5588 0.9999 221125_WJC_METTL3_EV_vs_WT_F06.15576.15576.3 9.15E-09 17/68 K.LK[136.11]SELVANNVTLPAGEQR[166.11].K "sp|P42166|LAP2A_HUMAN,sp|P42167|LAP2B_HUMAN,tr|G5E972|G5E972_HUMAN" 3 1956.0759 1.16 84514 15576 3 1956.077974 653.0326 "Lamina-associated polypeptide 2, isoform alpha OS=Homo sapiens OX=9606 GN=TMPO PE=1 SV=2" 6.14 2635.4 - 940033 - - - 1.0552 - 3.2 0.599 - 274.4 1 2 1 0.0021 18 0 0 0 5.44E+07 4.71E+07 - - - 8.114 0.9996 221125_WJC_METTL3_EV_vs_WT_F06.15577.15577.4 3.75E-06 22/90 K.ELVEFAQDDDRLREER.K sp|Q14677|EPN4_HUMAN 1 2018.9657 2.12 84515 15577 4 2018.968219 505.7487 Clathrin interactor 1 OS=Homo sapiens OX=9606 GN=CLINT1 PE=1 SV=1 4.2 2635.5 - 901589 - - - 1.2244 - 3.648 0.407 - 554.3 1 2 2 0.0025 16 0 0 0 2.07E+07 9.76E+06 - - - 3.2237 0.9999 221125_WJC_METTL3_EV_vs_WT_F06.15578.15578.4 1.03E-08 21/84 K.AFIAHFQDNLHSVNR.D "sp|Q6P2C8|MED27_HUMAN,tr|A0A494C0P0|A0A494C0P0_HUMAN,tr|A0A494C0K7|A0A494C0K7_HUMAN" 3 1767.8805 1.09 84516 15578 4 1767.884607 442.9774 Mediator of RNA polymerase II transcription subunit 27 OS=Homo sapiens OX=9606 GN=MED27 PE=1 SV=1 6.96 2635.6 - 511928 - - - 2.3226 - 3.317 0.463 - 404.5 1 2 0 0.0041 15 0 0 0 7.55E+06 6.92E+06 - - - 3.6839 1 221125_WJC_METTL3_EV_vs_WT_F06.15580.15580.3 2.36E-09 17/68 K.INQVFHGSC[160.03]ITEGNELTK[136.11].T sp|P78527|PRKDC_HUMAN 1 2053.9982 1.1 84518 15580 3 2054.001341 685.6734 DNA-dependent protein kinase catalytic subunit OS=Homo sapiens OX=9606 GN=PRKDC PE=1 SV=3 5.4 2635.9 - 429682 - - - 1.5097 - 3.433 0.532 - 433.7 1 2 0 0.0031 18 0 0 0 1.61E+07 1.47E+07 - - - 7.5418 0.9999 221125_WJC_METTL3_EV_vs_WT_F06.15586.15586.3 4.26E-05 15/52 K.SQIHDIVLVGGSTR[166.11].L "sp|P11142|HSP7C_HUMAN,tr|E9PNE6|E9PNE6_HUMAN,tr|A8K7Q2|A8K7Q2_HUMAN,tr|E9PKE3|E9PKE3_HUMAN,tr|E9PN89|E9PN89_HUMAN" 5 1490.8081 0.15 84522 15586 3 1490.811987 497.9433 Heat shock cognate 71 kDa protein OS=Homo sapiens OX=9606 GN=HSPA8 PE=1 SV=1 6.46 2636.7 - 5.98E+06 - - - 2.6335 - 2.561 0.494 - 273.6 1 2 0 0.0039 14 0 0 0 2.50E+08 1.70E+09 - - - 6.5457 0.9987 221125_WJC_METTL3_EV_vs_WT_F06.15588.15588.3 0.0137 Oct-44 R.DLDELSRYPEDK.L "sp|P43243|MATR3_HUMAN,tr|A8MXP9|A8MXP9_HUMAN,tr|D6R991|D6R991_HUMAN,tr|A0A0R4J2E8|A0A0R4J2E8_HUMAN,tr|D6REM6|D6REM6_HUMAN" 5 1478.6889 1.28 84524 15588 3 1478.691645 493.9036 Matrin-3 OS=Homo sapiens OX=9606 GN=MATR3 PE=1 SV=2 4.11 2636.8 - 1.97E+06 - - - 1.8543 - 1.883 0.403 - 96.6 1 2 1 0.0027 12 0 0 0 7.24E+07 5.65E+07 - - - 4.7865 0.998 221125_WJC_METTL3_EV_vs_WT_F06.15589.15589.3 1.04E-06 16/56 T.HISDTSVVLSMDNNR.N "sp|P48668|K2C6C_HUMAN,sp|P12035|K2C3_HUMAN,sp|P04259|K2C6B_HUMAN,sp|P02538|K2C6A_HUMAN" 4 1686.7995 126.98 84525 15589 3 1686.801778 563.2738 "Keratin, type II cytoskeletal 6C OS=Homo sapiens OX=9606 GN=KRT6C PE=1 SV=3" 5.21 2636.9 - 1.81E+06 - - - 1.3309 - 3.094 0.544 - 459.6 1 1 0 0.0022 15 0 0 0 2.25E+07 1.77E+05 - - - 7.5516 0.9959 221125_WJC_METTL3_EV_vs_WT_F06.15591.15591.3 0.00665 Oct-60 K.ELVEFAQDDDRLREER.K sp|Q14677|EPN4_HUMAN 1 2018.9657 0.82 84527 15591 3 2018.970766 673.9959 Clathrin interactor 1 OS=Homo sapiens OX=9606 GN=CLINT1 PE=1 SV=1 4.2 2637 - 615563 - - - 2.4859 - 2.141 0.327 - 104.5 1 2 2 0.005 16 0 0 0 7.97E+06 9.72E+06 - - - 4.1377 0.9995 221125_WJC_METTL3_EV_vs_WT_F06.15592.15592.4 4.77E-05 Nov-84 K.DKFNEC[160.03]GHVLYADIK.M "sp|P52272|HNRPM_HUMAN,tr|A0A087X0X3|A0A087X0X3_HUMAN" 2 1807.8563 1.48 84528 15592 4 1807.86048 452.9714 Heterogeneous nuclear ribonucleoprotein M OS=Homo sapiens OX=9606 GN=HNRNPM PE=1 SV=3 5.38 2637.2 - 600230 - - - 2.3011 - 2.398 0.452 - 74.1 1 2 1 0.0042 15 0 0 0 9.56E+06 6.47E+06 - - - 3.472 0.9998 221125_WJC_METTL3_EV_vs_WT_F06.15593.15593.4 5.45E-05 14/84 K.AQILVAKPELKDPIR.K sp|Q14781|CBX2_HUMAN 1 1690.0141 1.56 84529 15593 4 1690.015449 423.5108 Chromobox protein homolog 2 OS=Homo sapiens OX=9606 GN=CBX2 PE=1 SV=2 8.63 2637.3 - 507097 - - - 0.774 - 2.938 0.484 - 134 1 2 1 0.0013 15 0 0 0 4.44E+06 2.84E+06 - - - 3.824 0.9993 221125_WJC_METTL3_EV_vs_WT_F06.15594.15594.3 2.59E-05 16/72 K.ITK[136.11]PGSIDSNNQLFAPGGR[166.11].L "sp|Q04637|IF4G1_HUMAN,tr|E7EUU4|E7EUU4_HUMAN,tr|E9PGM1|E9PGM1_HUMAN,tr|E7EX73|E7EX73_HUMAN,tr|A0A7I2Y1C3|A0A7I2Y1C3_HUMAN" 5 1989.0399 0.96 84530 15594 3 1989.048916 664.0206 Eukaryotic translation initiation factor 4 gamma 1 OS=Homo sapiens OX=9606 GN=EIF4G1 PE=1 SV=4 8.75 2637.4 - 481427 - - - 4.554 - 2.662 0.426 - 230.5 1 2 0 0.0091 19 0 0 0 6.48E+07 6.75E+07 - - - 5.6924 0.9997 221125_WJC_METTL3_EV_vs_WT_F06.15595.15595.4 1.51E-06 17/84 K.AQILVAK[136.11]PELK[136.11]DPIR[166.11].K sp|Q14781|CBX2_HUMAN 1 1716.0508 1.56 84531 15595 4 1716.054397 430.02 Chromobox protein homolog 2 OS=Homo sapiens OX=9606 GN=CBX2 PE=1 SV=2 8.63 2637.6 - 413717 - - - 2.0897 - 2.565 0.482 - 226.2 1 2 1 0.0036 15 0 0 0 4.44E+06 2.84E+06 - - - 3.7574 1 221125_WJC_METTL3_EV_vs_WT_F06.15596.15596.3 9.94E-14 23/60 R.HEMPPHIYAITDTAYR[166.11].S "sp|P35579|MYH9_HUMAN,tr|Q5BKV1|Q5BKV1_HUMAN" 2 1923.9177 0.94 84532 15596 3 1923.915406 642.3132 Myosin-9 OS=Homo sapiens OX=9606 GN=MYH9 PE=1 SV=4 5.99 2637.7 - 404996 - - - -1.1861 - 4.012 0.711 - 694.8 1 2 0 -0.0023 16 0 0 0 8.58E+06 9.15E+06 - - - 10.031 0.9998 221125_WJC_METTL3_EV_vs_WT_F06.15597.15597.4 2.56E-07 15/84 K.AAHIFNEALVC[160.03]HQIR[166.11].Y "sp|O43795|MYO1B_HUMAN,tr|E9PDF6|E9PDF6_HUMAN" 2 1787.9129 2.98 84533 15597 4 1787.919533 447.9855 Unconventional myosin-Ib OS=Homo sapiens OX=9606 GN=MYO1B PE=1 SV=3 6.95 2637.8 - 287895 - - - 3.7228 - 3.237 0.511 - 312.2 1 2 0 0.0067 15 0 0 0 6.88E+06 2.31E+06 - - - 4.0922 0.9999 221125_WJC_METTL3_EV_vs_WT_F06.15601.15601.3 1.72E-06 Dec-56 K.K[136.11]LEEEQIILEDQNC[160.03]K[136.11].L sp|P35579|MYH9_HUMAN 1 1903.9532 1.12 84535 15601 3 1903.96032 635.6583 Myosin-9 OS=Homo sapiens OX=9606 GN=MYH9 PE=1 SV=4 4.25 2638.3 - 2.96E+06 - - - 3.7427 - 2.86 0.535 - 252.9 1 2 0 0.0071 15 0 0 0 9.56E+07 8.51E+07 - - - 7.2447 0.9998 221125_WJC_METTL3_EV_vs_WT_F06.15602.15602.3 7.11E-05 13/44 R.DLDELSR[166.11]YPEDK[136.11].L "sp|P43243|MATR3_HUMAN,tr|A8MXP9|A8MXP9_HUMAN,tr|D6R991|D6R991_HUMAN,tr|A0A0R4J2E8|A0A0R4J2E8_HUMAN,tr|D6REM6|D6REM6_HUMAN" 5 1496.7114 1.29 84536 15602 3 1496.713834 499.9111 Matrin-3 OS=Homo sapiens OX=9606 GN=MATR3 PE=1 SV=2 4.11 2638.4 - 2.45E+06 - - - 1.6443 - 2.56 0.498 - 158.5 1 2 1 0.0025 12 0 0 0 7.28E+07 5.66E+07 - - - 6.6971 0.9997 221125_WJC_METTL3_EV_vs_WT_F06.15603.15603.4 1.42E-06 16/96 K.AGK[136.11]FPSLLTHNENMVAK[136.11].V sp|P62906|RL10A_HUMAN 1 1871.9899 0.99 84537 15603 4 1871.995207 469.0047 60S ribosomal protein L10a OS=Homo sapiens OX=9606 GN=RPL10A PE=1 SV=2 8.64 2638.5 - 1.63E+06 - - - 2.8601 - 2.886 0.516 - 161.5 1 2 1 0.0054 17 0 0 0 7.12E+07 7.17E+07 - - - 4.0838 0.9998 221125_WJC_METTL3_EV_vs_WT_F06.15604.15604.4 4.61E-05 18/90 K.ELVEFAQDDDR[166.11]LR[166.11]EER[166.11].K sp|Q14677|EPN4_HUMAN 1 2048.9906 2.12 84538 15604 4 2048.991968 513.2549 Clathrin interactor 1 OS=Homo sapiens OX=9606 GN=CLINT1 PE=1 SV=1 4.2 2638.5 - 1.50E+06 - - - 0.6886 - 3.135 0.467 - 349.2 1 2 2 0.0014 16 0 0 0 2.07E+07 9.76E+06 - - - 3.6929 0.9994 221125_WJC_METTL3_EV_vs_WT_F06.15606.15606.4 0.000889 19/84 K.AFIAHFQDNLHSVNR[166.11].D "sp|Q6P2C8|MED27_HUMAN,tr|A0A494C0P0|A0A494C0P0_HUMAN,tr|A0A494C0K7|A0A494C0K7_HUMAN" 3 1777.8888 1.09 84540 15606 4 1777.892715 445.4795 Mediator of RNA polymerase II transcription subunit 27 OS=Homo sapiens OX=9606 GN=MED27 PE=1 SV=1 6.96 2638.7 - 1.15E+06 - - - 2.2184 - 2.977 0.339 - 235.8 1 2 0 0.0039 15 0 0 0 7.55E+06 6.92E+06 - - - 2.5659 0.9998 221125_WJC_METTL3_EV_vs_WT_F06.15608.15608.2 1.04E-05 20-Oct R.EEAENTLQSFR[166.11].Q "sp|P08670|VIME_HUMAN,tr|B0YJC5|B0YJC5_HUMAN,tr|B0YJC4|B0YJC4_HUMAN" 3 1332.6185 2.37 84542 15608 2 1332.618055 667.3165 Vimentin OS=Homo sapiens OX=9606 GN=VIM PE=1 SV=4 4.25 2638.9 - 917687 - - - -0.3557 - 2.225 0.409 - 548.1 1 2 0 -0.0005 11 0 0 0 2.40E+07 1.01E+07 - - - 4.2253 0.9997 221125_WJC_METTL3_EV_vs_WT_F06.15609.15609.2 0.000401 28-Dec R.VSSSC[160.03]LDLPDSTEEK.G sp|Q5VT52|RPRD2_HUMAN 1 1665.7403 2.05 84543 15609 2 1665.743882 833.8774 Regulation of nuclear pre-mRNA domain-containing protein 2 OS=Homo sapiens OX=9606 GN=RPRD2 PE=1 SV=1 3.92 2639 - 717220 - - - 2.1222 - 2.747 0.477 - 368.2 1 2 0 0.0035 15 0 0 0 7.08E+06 3.46E+06 - - - 5.0474 0.9999 221125_WJC_METTL3_EV_vs_WT_F06.15610.15610.3 5.54E-05 15/48 R.K[136.11]PASFMTSIC[160.03]DER[166.11].G sp|P53396|ACLY_HUMAN 1 1558.7239 4.58 84544 15610 3 1558.727983 520.5819 ATP-citrate synthase OS=Homo sapiens OX=9606 GN=ACLY PE=1 SV=3 6.06 2639.1 - 618168 - - - 2.6393 - 2.842 0.524 - 360.3 1 2 0 0.0041 13 0 0 0 2.83E+07 6.17E+06 - - - 7.2129 1 221125_WJC_METTL3_EV_vs_WT_F06.15611.15611.3 3.21E-10 20/60 R.HEMPPHIYAITDTAYR.S "sp|P35579|MYH9_HUMAN,tr|Q5BKV1|Q5BKV1_HUMAN" 2 1913.9094 0.94 84545 15611 3 1913.91244 638.9771 Myosin-9 OS=Homo sapiens OX=9606 GN=MYH9 PE=1 SV=4 5.99 2639.2 - 421089 - - - 1.579 - 3.668 0.609 - 516.4 1 2 0 0.003 16 0 0 0 8.58E+06 9.15E+06 - - - 8.6636 0.9999 221125_WJC_METTL3_EV_vs_WT_F06.15612.15612.2 4.79E-07 28-Oct R.VSSSC[160.03]LDLPDSTEEK[136.11].G sp|Q5VT52|RPRD2_HUMAN 1 1673.7545 2.05 84546 15612 2 1673.752359 837.8845 Regulation of nuclear pre-mRNA domain-containing protein 2 OS=Homo sapiens OX=9606 GN=RPRD2 PE=1 SV=1 3.92 2639.4 - 328409 - - - -1.3072 - 2.553 0.583 - 223.6 1 2 0 -0.0022 15 0 0 0 7.08E+06 3.46E+06 - - - 5.6507 1 221125_WJC_METTL3_EV_vs_WT_F06.15613.15613.2 7.72E-11 15/22 R.DLDELSR[166.11]YPEDK[136.11].L "sp|P43243|MATR3_HUMAN,tr|A8MXP9|A8MXP9_HUMAN,tr|D6R991|D6R991_HUMAN,tr|A0A0R4J2E8|A0A0R4J2E8_HUMAN,tr|D6REM6|D6REM6_HUMAN" 5 1496.7114 1.25 84547 15613 2 1496.715772 749.363 Matrin-3 OS=Homo sapiens OX=9606 GN=MATR3 PE=1 SV=2 4.11 2639.5 - 310805 - - - 2.9391 - 3.23 0.666 - 710.5 1 2 1 0.0044 12 0 0 0 1.01E+07 8.10E+06 - - - 7.0437 0.8643 221125_WJC_METTL3_EV_vs_WT_F06.15614.15614.2 2.40E-07 30-Sep K.EQASHLGGAVFSGAGN.L "sp|Q16143|SYUB_HUMAN,tr|G4Y816|G4Y816_HUMAN" 2 1500.6957 - 84548 15614 2 1500.703665 751.3551 Beta-synuclein OS=Homo sapiens OX=9606 GN=SNCB PE=1 SV=1 5.24 2639.6 - 302017 - - - 5.2942 - 2.306 0.54 - 183.1 1 1 0 0.0079 16 0 0 0 - - - - - 5.0811 0.9997 221125_WJC_METTL3_EV_vs_WT_F06.15616.15616.2 0.000494 30-Dec K.AHLMEIQVNGGTVAEK.L "sp|P39023|RL3_HUMAN,tr|G5E9G0|G5E9G0_HUMAN,tr|H7C3M2|H7C3M2_HUMAN,tr|B5MCW2|B5MCW2_HUMAN,tr|H7C422|H7C422_HUMAN" 5 1695.8614 0.62 84550 15616 2 1695.865699 848.938 60S ribosomal protein L3 OS=Homo sapiens OX=9606 GN=RPL3 PE=1 SV=2 5.4 2639.9 - 193598 - - - 2.532 - 2.748 0.55 - 300 1 2 0 0.0043 16 0 0 0 8.08E+05 1.30E+06 - - - 5.5872 1 221125_WJC_METTL3_EV_vs_WT_F06.15619.15619.3 5.16E-08 19/68 K.AGVSISVVHGNLSEEAAK.Q sp|P36551|HEM6_HUMAN 1 1766.9163 1.31 84551 15619 3 1766.918947 589.9794 "Oxygen-dependent coproporphyrinogen-III oxidase, mitochondrial OS=Homo sapiens OX=9606 GN=CPOX PE=1 SV=3" 5.4 2640.3 - 4.50E+06 - - - 1.5111 - 3.763 0.565 - 642.1 1 2 0 0.0027 18 0 0 0 5.44E+07 4.14E+07 - - - 8.1384 0.9993 221125_WJC_METTL3_EV_vs_WT_F06.15620.15620.3 0.0745 13/68 K.AGVSISVVHGNLSEEAAK[136.11].Q sp|P36551|HEM6_HUMAN 1 1774.9305 1.31 84552 15620 3 1774.933607 592.6508 "Oxygen-dependent coproporphyrinogen-III oxidase, mitochondrial OS=Homo sapiens OX=9606 GN=CPOX PE=1 SV=3" 5.4 2640.4 - 4.55E+06 - - - 1.7634 - 2.535 0.274 - 125 1 2 0 0.0031 18 0 0 0 5.44E+07 4.14E+07 - - - 3.9102 0.9998 221125_WJC_METTL3_EV_vs_WT_F06.15621.15621.3 6.25E-07 13/64 K.AGK[136.11]FPSLLTHNENMVAK[136.11].V sp|P62906|RL10A_HUMAN 1 1871.9899 1.26 84553 15621 3 1871.993727 625.0039 60S ribosomal protein L10a OS=Homo sapiens OX=9606 GN=RPL10A PE=1 SV=2 8.64 2640.4 - 2.59E+06 - - - 2.0695 - 2.554 0.515 - 130.9 1 2 1 0.0039 17 0 0 0 6.44E+07 5.11E+07 - - - 6.6495 1 221125_WJC_METTL3_EV_vs_WT_F06.15622.15622.3 1.41E-10 15/56 K.DKFNEC[160.03]GHVLYADIK.M "sp|P52272|HNRPM_HUMAN,tr|A0A087X0X3|A0A087X0X3_HUMAN" 2 1807.8563 2.55 84554 15622 3 1807.857778 603.626 Heterogeneous nuclear ribonucleoprotein M OS=Homo sapiens OX=9606 GN=HNRNPM PE=1 SV=3 5.38 2640.5 - 1.63E+06 - - - 0.8065 - 3.068 0.654 - 204.6 1 2 1 0.0015 15 0 0 0 1.46E+07 5.73E+06 - - - 8.7562 0.998 221125_WJC_METTL3_EV_vs_WT_F06.15624.15624.4 0.00606 Dec-84 K.DK[136.11]FNEC[160.03]GHVLYADIK[136.11].M "sp|P52272|HNRPM_HUMAN,tr|A0A087X0X3|A0A087X0X3_HUMAN" 2 1823.8847 1.51 84556 15624 4 1823.888941 456.9785 Heterogeneous nuclear ribonucleoprotein M OS=Homo sapiens OX=9606 GN=HNRNPM PE=1 SV=3 5.38 2640.7 - 1.23E+06 - - - 2.3143 - 2.275 0.363 - 117.4 1 2 1 0.0042 15 0 0 0 9.56E+06 6.32E+06 - - - 2.6785 1 221125_WJC_METTL3_EV_vs_WT_F06.15625.15625.2 4.59E-12 16/34 R.STSGFC[160.03]QGGGVGGFGGGR.G "sp|Q7Z794|K2C1B_HUMAN,tr|F8VS61|F8VS61_HUMAN" 2 1643.7111 999 84557 15625 2 1643.713434 822.8628 "Keratin, type II cytoskeletal 1b OS=Homo sapiens OX=9606 GN=KRT77 PE=1 SV=3" 7.96 2640.8 - 922025 - - - 1.4486 - 3.443 0.72 - 658.5 1 2 0 0.0024 18 0 0 0 2.12E+07 0.00E+00 - - - 7.3978 0.9999 221125_WJC_METTL3_EV_vs_WT_F06.15626.15626.3 0.000489 15/52 K.LTFDSSFSPNTGKK.N "sp|P21796|VDAC1_HUMAN,tr|C9JI87|C9JI87_HUMAN" 2 1527.7569 1.34 84558 15626 3 1527.762028 510.2596 Voltage-dependent anion-selective channel protein 1 OS=Homo sapiens OX=9606 GN=VDAC1 PE=1 SV=2 8.59 2640.9 - 886289 - - - 3.3415 - 2.826 0.506 - 203.1 1 2 0 0.0051 14 0 0 0 5.27E+08 3.93E+08 - - - 6.9408 0.9999 221125_WJC_METTL3_EV_vs_WT_F06.15627.15627.3 6.60E-06 Dec-52 K.LTFDSSFSPNTGK[136.11]K[136.11].N "sp|P21796|VDAC1_HUMAN,tr|C9JI87|C9JI87_HUMAN" 2 1543.7853 1.34 84559 15627 3 1543.788287 515.6024 Voltage-dependent anion-selective channel protein 1 OS=Homo sapiens OX=9606 GN=VDAC1 PE=1 SV=2 8.59 2641 - 786172 - - - 1.92 - 2.396 0.482 - 112.5 1 2 0 0.003 14 0 0 0 5.27E+08 3.93E+08 - - - 6.2352 0.9997 221125_WJC_METTL3_EV_vs_WT_F06.15630.15630.4 6.20E-05 13/84 R.YAGLLFSSR[166.11]PDAHDR[166.11].M "sp|P28340|DPOD1_HUMAN,tr|M0QZR8|M0QZR8_HUMAN,tr|M0QXQ2|M0QXQ2_HUMAN,tr|M0QXE6|M0QXE6_HUMAN,tr|M0R2B7|M0R2B7_HUMAN,tr|A0A087WYJ2|A0A087WYJ2_HUMAN" 6 1723.8545 0.52 84562 15630 4 1723.856251 431.9709 DNA polymerase delta catalytic subunit OS=Homo sapiens OX=9606 GN=POLD1 PE=1 SV=2 6.75 2641.4 - 451291 - - - 1.0117 - 2.271 0.363 - 89.5 1 2 0 0.0017 15 0 0 0 2.76E+06 5.31E+06 - - - 2.6786 0.9999 221125_WJC_METTL3_EV_vs_WT_F06.15632.15632.2 8.86E-07 Oct-42 K.ASAEGPLLGPEAAPSGEGAGSK[136.11].G "sp|Q9BRJ6|CG050_HUMAN,tr|C9JQV0|C9JQV0_HUMAN" 2 1959.9629 1.36 84564 15632 2 1959.964046 980.9887 Uncharacterized protein C7orf50 OS=Homo sapiens OX=9606 GN=C7orf50 PE=1 SV=1 4.25 2641.6 - 223671 - - - 0.5847 - 2.391 0.532 - 163.7 1 2 0 0.0011 22 0 0 0 4.13E+06 3.04E+06 - - - 5.1131 0.7738 221125_WJC_METTL3_EV_vs_WT_F06.15638.15638.2 3.73 30-Apr K.AHLMEIQVNGGTVAEK[136.11].L "sp|P39023|RL3_HUMAN,tr|G5E9G0|G5E9G0_HUMAN,tr|H7C3M2|H7C3M2_HUMAN,tr|B5MCW2|B5MCW2_HUMAN,tr|H7C422|H7C422_HUMAN" 5 1703.8756 0.62 84570 15638 2 1703.879441 852.9451 60S ribosomal protein L3 OS=Homo sapiens OX=9606 GN=RPL3 PE=1 SV=2 5.4 2642.4 - 117928 - - - 2.2513 - 0.835 0.09 - 37.7 2 2 0 0.0038 16 0 0 0 8.08E+05 1.30E+06 - - - -0.8733 0.9999 221125_WJC_METTL3_EV_vs_WT_F06.15645.15645.3 4.45E-06 Nov-48 K.AQHPDYSFGELSR.L "sp|Q86U86|PB1_HUMAN,tr|E7EVG2|E7EVG2_HUMAN" 2 1505.6899 1.62 84575 15645 3 1505.689968 502.9039 Protein polybromo-1 OS=Homo sapiens OX=9606 GN=PBRM1 PE=1 SV=1 5.32 2643 - 1.74E+06 - - - 0.0412 - 2.128 0.467 - 140.4 1 2 0 0.0001 13 0 0 0 1.46E+08 9.00E+07 - - - 5.7941 0.9994 221125_WJC_METTL3_EV_vs_WT_F06.15647.15647.2 1.69E-07 14/30 R.ELNNSTNGIVIEPSEK.A "sp|Q14681|KCTD2_HUMAN,tr|J3QSC8|J3QSC8_HUMAN" 2 1742.8687 8.71 84577 15647 2 1742.874936 872.4416 BTB\POZ domain-containing protein KCTD2 OS=Homo sapiens OX=9606 GN=KCTD2 PE=1 SV=3 4.25 2643.2 - 1.43E+06 - - - 3.6015 - 2.811 0.522 - 317 1 2 0 0.0063 16 0 0 0 4.15E+07 4.77E+06 - - - 5.4355 1 221125_WJC_METTL3_EV_vs_WT_F06.15648.15648.3 2.18E-07 Dec-60 R.AVDPDGDGHVSWDEYK.V "sp|Q9BRK5|CAB45_HUMAN,tr|A0A5F9UJX7|A0A5F9UJX7_HUMAN,tr|A0A5F9UP49|A0A5F9UP49_HUMAN,tr|G3V1E2|G3V1E2_HUMAN,tr|H0Y3T6|H0Y3T6_HUMAN" 5 1788.7591 1.55 84578 15648 3 1788.762402 597.2603 45 kDa calcium-binding protein OS=Homo sapiens OX=9606 GN=SDF4 PE=1 SV=1 4.03 2643.3 - 1.37E+06 - - - 1.8415 - 2.728 0.652 - 134.8 1 2 0 0.0033 16 0 0 0 2.10E+07 1.36E+07 - - - 8.3833 1 221125_WJC_METTL3_EV_vs_WT_F06.15651.15651.2 7.03E-06 14/22 R.DLDELSRYPEDK.L "sp|P43243|MATR3_HUMAN,tr|A8MXP9|A8MXP9_HUMAN,tr|D6R991|D6R991_HUMAN,tr|A0A0R4J2E8|A0A0R4J2E8_HUMAN,tr|D6REM6|D6REM6_HUMAN" 5 1478.6889 1.8 84581 15651 2 1478.691603 740.3517 Matrin-3 OS=Homo sapiens OX=9606 GN=MATR3 PE=1 SV=2 4.11 2643.6 - 737125 - - - 1.8259 - 3.062 0.599 - 606.2 1 2 1 0.0027 12 0 0 0 2.61E+07 1.46E+07 - - - 6.4088 0.9725 221125_WJC_METTL3_EV_vs_WT_F06.15652.15652.3 0.0231 Dec-60 R.ELNNSTNGIVIEPSEK.A "sp|Q14681|KCTD2_HUMAN,tr|J3QSC8|J3QSC8_HUMAN" 2 1742.8687 3.8 84582 15652 3 1742.876942 581.9635 BTB\POZ domain-containing protein KCTD2 OS=Homo sapiens OX=9606 GN=KCTD2 PE=1 SV=3 4.25 2643.7 - 627006 - - - 4.7525 - 2.068 0.217 - 161.4 1 2 0 0.0083 16 0 0 0 1.34E+07 3.52E+06 - - - 2.8214 0.9997 221125_WJC_METTL3_EV_vs_WT_F06.15653.15653.4 0.000182 Nov-84 R.YAGLLFSSRPDAHDR.M "sp|P28340|DPOD1_HUMAN,tr|M0QZR8|M0QZR8_HUMAN,tr|M0QXQ2|M0QXQ2_HUMAN,tr|M0QXE6|M0QXE6_HUMAN,tr|M0R2B7|M0R2B7_HUMAN,tr|A0A087WYJ2|A0A087WYJ2_HUMAN" 6 1703.838 0.56 84583 15653 4 1703.842578 426.9668 DNA polymerase delta catalytic subunit OS=Homo sapiens OX=9606 GN=POLD1 PE=1 SV=2 6.75 2643.9 - 488172 - - - 2.7062 - 1.805 0.423 - 64.9 1 2 0 0.0046 15 0 0 0 3.06E+06 5.50E+06 - - - 3.1178 1 221125_WJC_METTL3_EV_vs_WT_F06.15654.15654.2 3.00E-11 16/42 K.ASAEGPLLGPEAAPSGEGAGSK.G "sp|Q9BRJ6|CG050_HUMAN,tr|C9JQV0|C9JQV0_HUMAN" 2 1951.9487 1.36 84584 15654 2 1951.955723 976.9816 Uncharacterized protein C7orf50 OS=Homo sapiens OX=9606 GN=C7orf50 PE=1 SV=1 4.25 2644 - 313991 - - - 3.5979 - 2.918 0.661 - 411.4 1 2 0 0.007 22 0 0 0 4.13E+06 3.04E+06 - - - 6.5538 1 221125_WJC_METTL3_EV_vs_WT_F06.15655.15655.2 1.02E-13 16/38 R.FSSC[160.03]GGGGGSFGAGGGFGSR.S sp|P04264|K2C1_HUMAN 1 1764.7274 999 84585 15655 2 1764.728415 883.371 "Keratin, type II cytoskeletal 1 OS=Homo sapiens OX=9606 GN=KRT1 PE=1 SV=6" 8.25 2644.1 - 309259 - - - 0.5576 - 3.776 0.786 - 710.2 1 2 0 0.001 20 0 0 0 5.16E+06 0.00E+00 - - - 8.1127 0.9999 221125_WJC_METTL3_EV_vs_WT_F06.15657.15657.2 1.82E-07 30-Oct K.GGKPEPPAMPQPVPTA.- "sp|P23396|RS3_HUMAN,tr|H0YEU2|H0YEU2_HUMAN,tr|E9PL09|E9PL09_HUMAN,tr|E9PPU1|E9PPU1_HUMAN" 4 1572.797 0.82 84587 15657 2 1572.797758 787.4058 40S ribosomal protein S3 OS=Homo sapiens OX=9606 GN=RPS3 PE=1 SV=2 6 2644.4 - 273116 - - - 0.473 - 1.958 0.577 - 168.3 1 2 0 0.0007 16 0 0 0 1.84E+08 2.25E+08 - - - 4.9544 0.9997 221125_WJC_METTL3_EV_vs_WT_F06.15658.15658.2 1.62E-05 Oct-34 K.AGVSISVVHGNLSEEAAK[136.11].Q sp|P36551|HEM6_HUMAN 1 1774.9305 1.14 84588 15658 2 1774.93306 888.4725 "Oxygen-dependent coproporphyrinogen-III oxidase, mitochondrial OS=Homo sapiens OX=9606 GN=CPOX PE=1 SV=3" 5.4 2644.5 - 242424 - - - 1.4553 - 2.421 0.391 - 233.2 1 2 0 0.0026 18 0 0 0 1.43E+06 1.25E+06 - - - 4.1019 0.9999 221125_WJC_METTL3_EV_vs_WT_F06.15661.15661.4 1.01E-08 14/96 K.AGKFPSLLTHNENMVAK.V sp|P62906|RL10A_HUMAN 1 1855.9615 0.98 84590 15661 4 1855.965027 464.9976 60S ribosomal protein L10a OS=Homo sapiens OX=9606 GN=RPL10A PE=1 SV=2 8.64 2644.9 - 1.11E+07 - - - 1.9257 - 3.203 0.562 - 141.2 1 2 1 0.0036 17 0 0 0 6.97E+07 7.11E+07 - - - 4.5208 0.9989 221125_WJC_METTL3_EV_vs_WT_F06.15665.15665.2 4.12E-09 17/20 K.TTLLHMLK[136.11]DDR[166.11].L "sp|Q9NR31|SAR1A_HUMAN,sp|Q9Y6B6|SAR1B_HUMAN,tr|D6RAA2|D6RAA2_HUMAN,tr|D6RD69|D6RD69_HUMAN,tr|X1WI22|X1WI22_HUMAN,tr|Q5SQT8|Q5SQT8_HUMAN,tr|D6RDB2|D6RDB2_HUMAN" 7 1359.7299 1.06 84593 15665 2 1359.730853 680.8722 GTP-binding protein SAR1a OS=Homo sapiens OX=9606 GN=SAR1A PE=1 SV=1 6.41 2645.3 - 1.94E+06 - - - 0.6707 - 3.078 0.462 - 1329 1 2 1 0.0009 11 0 0 0 4.25E+07 4.02E+07 - - - 5.4945 0.9992 221125_WJC_METTL3_EV_vs_WT_F06.15669.15669.3 0.00651 13/44 K.STVTLSWKPVQK.V "sp|Q9BZZ5|API5_HUMAN,tr|H0YER7|H0YER7_HUMAN,tr|G3V1C3|G3V1C3_HUMAN" 3 1372.7715 2.57 84597 15669 3 1372.774777 458.5978 Apoptosis inhibitor 5 OS=Homo sapiens OX=9606 GN=API5 PE=1 SV=3 10 2645.6 - 1.50E+06 - - - 2.4228 - 2.312 0.298 - 263.8 1 2 0 0.0033 12 0 0 0 7.90E+06 3.07E+06 - - - 4.1846 1 221125_WJC_METTL3_EV_vs_WT_F06.15670.15670.4 0.000108 22/102 R.VIAPSSSLPTSLTIHHPR.E sp|Q02413|DSG1_HUMAN 1 1912.053 999 84598 15670 4 1912.05551 479.0205 Desmoglein-1 OS=Homo sapiens OX=9606 GN=DSG1 PE=1 SV=2 9.73 2645.7 - 1.43E+06 - - - 1.2887 - 3.969 0.516 - 548.5 1 2 0 0.0025 18 0 0 0 3.54E+08 0.00E+00 - - - 4.1888 0.9939 221125_WJC_METTL3_EV_vs_WT_F06.15672.15672.3 0.00486 Nov-68 R.ISTYGLPAGGIQPHPQTK.N sp|Q9Y5K6|CD2AP_HUMAN 1 1863.9843 0.23 84600 15672 3 1863.993263 622.3354 CD2-associated protein OS=Homo sapiens OX=9606 GN=CD2AP PE=1 SV=1 8.6 2645.9 - 899469 - - - 4.8101 - 2.074 0.322 - 134 1 2 0 0.009 18 0 0 0 1.16E+07 5.16E+07 - - - 3.944 1 221125_WJC_METTL3_EV_vs_WT_F06.15673.15673.2 1.14E-09 15/30 K.EILGTAQSVGC[160.03]NVDGR.H sp|P30050|RL12_HUMAN 1 1674.7995 1.72 84601 15673 2 1674.804116 838.407 60S ribosomal protein L12 OS=Homo sapiens OX=9606 GN=RPL12 PE=1 SV=1 4.37 2646 - 790445 - - - 2.7364 - 3.075 0.658 - 728.3 1 2 0 0.0046 16 0 0 0 1.29E+07 7.50E+06 - - - 6.6612 1 221125_WJC_METTL3_EV_vs_WT_F06.15674.15674.3 3.07E-08 19/48 K.K[136.11]TGQPMINLYTDR[166.11].E "sp|P35637|FUS_HUMAN,tr|H3BPE7|H3BPE7_HUMAN" 2 1553.7991 1.3 84602 15674 3 1553.803917 518.9403 RNA-binding protein FUS OS=Homo sapiens OX=9606 GN=FUS PE=1 SV=1 8.59 2646.1 - 713456 - - - 3.1111 - 3.285 0.554 - 628.1 1 2 0 0.0048 13 0 0 0 4.28E+07 3.29E+07 - - - 7.9399 0.9775 221125_WJC_METTL3_EV_vs_WT_F06.15675.15675.3 0.000329 13/36 T.TLLHMLKDDR.L "sp|Q9NR31|SAR1A_HUMAN,sp|Q9Y6B6|SAR1B_HUMAN,tr|D6RAA2|D6RAA2_HUMAN,tr|D6RD69|D6RD69_HUMAN,tr|X1WI22|X1WI22_HUMAN,tr|Q5SQT8|Q5SQT8_HUMAN,tr|D6RDB2|D6RDB2_HUMAN" 7 1240.6598 1.18 84603 15675 3 1240.659898 414.5605 GTP-binding protein SAR1a OS=Homo sapiens OX=9606 GN=SAR1A PE=1 SV=1 6.41 2646.3 - 618520 - - - 0.0854 - 2.257 0.452 - 302.1 1 1 1 0.0001 10 0 0 0 1.22E+07 1.03E+07 - - - 5.9567 1 221125_WJC_METTL3_EV_vs_WT_F06.15676.15676.2 9.68E-06 14/30 K.GGK[136.11]PEPPAMPQPVPTA.- "sp|P23396|RS3_HUMAN,tr|H0YEU2|H0YEU2_HUMAN,tr|E9PL09|E9PL09_HUMAN,tr|E9PPU1|E9PPU1_HUMAN" 4 1580.8112 0.82 84604 15676 2 1580.811762 791.4129 40S ribosomal protein S3 OS=Homo sapiens OX=9606 GN=RPS3 PE=1 SV=2 6 2646.4 - 471784 - - - 0.3467 - 2.523 0.601 - 307.1 1 2 0 0.0005 16 0 0 0 1.85E+08 2.26E+08 - - - 5.7551 0.9999 221125_WJC_METTL3_EV_vs_WT_F06.15678.15678.2 0.03 26-Nov K.LTFDSSFSPNTGK[136.11]K[136.11].N "sp|P21796|VDAC1_HUMAN,tr|C9JI87|C9JI87_HUMAN" 2 1543.7853 1.38 84606 15678 2 1543.784239 772.8999 Voltage-dependent anion-selective channel protein 1 OS=Homo sapiens OX=9606 GN=VDAC1 PE=1 SV=2 8.59 2646.6 - 375327 - - - -0.7022 - 2.499 0.532 - 335.1 1 2 0 -0.0011 14 0 0 0 3.60E+07 2.62E+07 - - - 5.2684 1 221125_WJC_METTL3_EV_vs_WT_F06.15681.15681.4 1.38E-05 14/72 K.R[166.11]LIDLHSPSEIVK[136.11].Q "sp|P60866|RS20_HUMAN,tr|A0A7P0S5H5|A0A7P0S5H5_HUMAN,tr|G3XAN0|G3XAN0_HUMAN" 3 1523.879 0.001 84609 15681 4 1523.878555 381.977 40S ribosomal protein S20 OS=Homo sapiens OX=9606 GN=RPS20 PE=1 SV=1 6.75 2647 - 198999 - - - -0.3235 - 2.545 0.487 - 160.8 1 2 0 -0.0005 13 0 0 0 0.00E+00 9.80E+06 - - - 3.8111 0.9909 221125_WJC_METTL3_EV_vs_WT_F06.15685.15685.2 0.000646 22-Sep K.DHTPSQELALTQ.S "sp|Q86U44|MTA70_HUMAN,tr|H0YFV6|H0YFV6_HUMAN" 2 1338.6416 - 84612 15685 2 1338.642099 670.3281 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 4.35 2647.5 - 6.86E+06 - - - 0.4034 - 2.125 0.48 - 273.9 1 1 0 0.0005 12 0 0 0 - - - - - 4.5694 1 221125_WJC_METTL3_EV_vs_WT_F06.15686.15686.3 4.19E-08 14/60 R.MTQNPNYYNLQGISHR.H sp|O75643|U520_HUMAN 1 1934.9057 1.89 84613 15686 3 1934.906911 645.9759 U5 small nuclear ribonucleoprotein 200 kDa helicase OS=Homo sapiens OX=9606 GN=SNRNP200 PE=1 SV=2 8.36 2647.5 - 4.82E+06 - - - 0.6109 - 2.815 0.587 - 260.8 1 2 0 0.0012 16 0 0 0 7.36E+07 3.89E+07 - - - 7.7397 1 221125_WJC_METTL3_EV_vs_WT_F06.15687.15687.3 1.90E-11 19/76 R.AHLTVGQAAAGGSGNLLTER.S sp|Q99959|PKP2_HUMAN 1 1921.997 1.61 84614 15687 3 1921.999506 641.6729 Plakophilin-2 OS=Homo sapiens OX=9606 GN=PKP2 PE=1 SV=2 6.79 2647.6 - 2.87E+06 - - - 1.3106 - 4.27 0.667 - 537.8 1 2 0 0.0025 20 0 0 0 6.04E+07 3.76E+07 - - - 9.4973 1 221125_WJC_METTL3_EV_vs_WT_F06.15690.15690.3 4.26E-09 22/68 R.VIAPSSSLPTSLTIHHPR.E sp|Q02413|DSG1_HUMAN 1 1912.053 999 84617 15690 3 1912.053265 638.3583 Desmoglein-1 OS=Homo sapiens OX=9606 GN=DSG1 PE=1 SV=2 9.73 2647.7 - 1.97E+06 - - - 0.1145 - 4.052 0.643 - 604 1 2 0 0.0002 18 0 0 0 1.03E+08 0.00E+00 - - - 9.1929 1 221125_WJC_METTL3_EV_vs_WT_F06.15691.15691.3 3.86E-10 20/72 K.SPMVEQAVQTGSADNLNAK.K "sp|Q9BX40|LS14B_HUMAN,tr|Q5TBP9|Q5TBP9_HUMAN,tr|Q5TBQ1|Q5TBQ1_HUMAN,tr|Q5TBQ0|Q5TBQ0_HUMAN" 4 1958.9368 0.96 84618 15691 3 1958.937994 653.9862 Protein LSM14 homolog B OS=Homo sapiens OX=9606 GN=LSM14B PE=1 SV=1 4.37 2647.8 - 1.85E+06 - - - 0.6325 - 4.055 0.614 - 695.3 1 2 0 0.0012 19 0 0 0 4.18E+07 4.37E+07 - - - 8.8246 0.9917 221125_WJC_METTL3_EV_vs_WT_F06.15692.15692.2 4.61 12-Jun R.SIFDHIK.L "sp|Q9NYF8|BCLF1_HUMAN,tr|E9PKI6|E9PKI6_HUMAN,tr|A0A1W2PQ43|A0A1W2PQ43_HUMAN,tr|E9PK91|E9PK91_HUMAN,tr|E9PJA7|E9PJA7_HUMAN,tr|E9PK09|E9PK09_HUMAN,tr|E9PQN2|E9PQN2_HUMAN" 7 858.46 1.72 84619 15692 2 858.460152 430.2373 Bcl-2-associated transcription factor 1 OS=Homo sapiens OX=9606 GN=BCLAF1 PE=1 SV=2 6.46 2647.9 - 1.58E+06 - - - 0.2318 - 1.056 0.21 - 90.6 1 2 0 0.0002 7 0 0 0 1.17E+07 6.78E+06 - - - 0.7646 0.9996 221125_WJC_METTL3_EV_vs_WT_F06.15694.15694.4 4.46E-06 20/90 K.GHFGPINSVAFHPDGK.S "sp|Q13347|EIF3I_HUMAN,tr|A0A7I2YQT9|A0A7I2YQT9_HUMAN,tr|A0A7I2V613|A0A7I2V613_HUMAN,tr|A0A7I2V3N2|A0A7I2V3N2_HUMAN,tr|A0A7I2YQU2|A0A7I2YQU2_HUMAN,tr|A0A7I2YQF8|A0A7I2YQF8_HUMAN,tr|A0A7I2V3U3|A0A7I2V3U3_HUMAN,tr|A0A7I2V607|A0A7I2V607_HUMAN,tr|A0A7I2V640|A0A7I2V640_HUMAN,tr|A0A7P0MRT9|A0A7P0MRT9_HUMAN,tr|A0A7I2V5V8|A0A7I2V5V8_HUMAN,tr|A0A7I2V2M3|A0A7I2V2M3_HUMAN,tr|A0A7I2V4C2|A0A7I2V4C2_HUMAN,tr|A0A7I2YQI2|A0A7I2YQI2_HUMAN,tr|A0A7I2YQC8|A0A7I2YQC8_HUMAN,tr|A0A7I2V685|A0A7I2V685_HUMAN" 16 1678.8216 1.05 84621 15694 4 1678.821817 420.7127 Eukaryotic translation initiation factor 3 subunit I OS=Homo sapiens OX=9606 GN=EIF3I PE=1 SV=1 6.92 2648.1 - 1.41E+06 - - - 0.1358 - 2.847 0.324 - 308.1 1 2 0 0.0002 16 0 0 0 3.79E+07 3.61E+07 - - - 2.4146 1 221125_WJC_METTL3_EV_vs_WT_F06.15695.15695.3 1.27E-05 15/48 K.KTGQPMINLYTDR.E "sp|P35637|FUS_HUMAN,tr|H3BPE7|H3BPE7_HUMAN" 2 1535.7766 1.3 84622 15695 3 1535.779139 512.9328 RNA-binding protein FUS OS=Homo sapiens OX=9606 GN=FUS PE=1 SV=1 8.59 2648.1 - 1.25E+06 - - - 1.6448 - 2.806 0.46 - 359.1 1 2 0 0.0025 13 0 0 0 4.09E+07 3.16E+07 - - - 6.4652 1 221125_WJC_METTL3_EV_vs_WT_F06.15696.15696.4 4.73E-05 17/66 R.VR[166.11]PGFC[160.03]FHLC[160.03]SR[166.11].A sp|Q08211|DHX9_HUMAN 1 1554.7451 0.79 84623 15696 4 1554.744052 389.6936 ATP-dependent RNA helicase A OS=Homo sapiens OX=9606 GN=DHX9 PE=1 SV=4 9.02 2648.3 - 618120 - - - -0.6728 - 2.585 0.488 - 278.6 1 2 0 -0.001 12 0 0 0 1.39E+07 1.76E+07 - - - 3.8327 1 221125_WJC_METTL3_EV_vs_WT_F06.15697.15697.2 2.58E-07 26-Dec K.LTFDSSFSPNTGKK.N "sp|P21796|VDAC1_HUMAN,tr|C9JI87|C9JI87_HUMAN" 2 1527.7569 1.38 84624 15697 2 1527.757119 764.8857 Voltage-dependent anion-selective channel protein 1 OS=Homo sapiens OX=9606 GN=VDAC1 PE=1 SV=2 8.59 2648.4 - 602330 - - - 0.1283 - 2.623 0.593 - 440.3 1 2 0 0.0002 14 0 0 0 3.60E+07 2.62E+07 - - - 5.8407 1 221125_WJC_METTL3_EV_vs_WT_F06.15700.15700.4 4.01E-07 15/66 R.VRPGFC[160.03]FHLC[160.03]SR.A sp|Q08211|DHX9_HUMAN 1 1534.7286 0.78 84627 15700 4 1534.729166 384.6894 ATP-dependent RNA helicase A OS=Homo sapiens OX=9606 GN=DHX9 PE=1 SV=4 9.02 2648.8 - 526988 - - - 0.3962 - 2.506 0.507 - 217.3 1 2 0 0.0006 12 0 0 0 1.37E+07 1.76E+07 - - - 3.9864 1 221125_WJC_METTL3_EV_vs_WT_F06.15701.15701.2 2.64E-13 18/36 K.SPMVEQAVQTGSADNLNAK.K "sp|Q9BX40|LS14B_HUMAN,tr|Q5TBP9|Q5TBP9_HUMAN,tr|Q5TBQ1|Q5TBQ1_HUMAN,tr|Q5TBQ0|Q5TBQ0_HUMAN" 4 1958.9368 0.84 84628 15701 2 1958.940061 980.4757 Protein LSM14 homolog B OS=Homo sapiens OX=9606 GN=LSM14B PE=1 SV=1 4.37 2648.9 - 378884 - - - 1.6877 - 4.102 0.748 - 1260.5 1 2 0 0.0033 19 0 0 0 9.80E+06 1.16E+07 - - - 8.0349 0.998 221125_WJC_METTL3_EV_vs_WT_F06.15706.15706.3 0.000549 13/40 K.TTLLHMLKDDR[166.11].L "sp|Q9NR31|SAR1A_HUMAN,sp|Q9Y6B6|SAR1B_HUMAN,tr|D6RAA2|D6RAA2_HUMAN,tr|D6RD69|D6RD69_HUMAN,tr|X1WI22|X1WI22_HUMAN,tr|Q5SQT8|Q5SQT8_HUMAN,tr|D6RDB2|D6RDB2_HUMAN" 7 1351.7157 - 84631 15706 3 1351.718617 451.5792 GTP-binding protein SAR1a OS=Homo sapiens OX=9606 GN=SAR1A PE=1 SV=1 6.41 2649.5 - 517802 - - - 2.1277 - 2.55 0.31 - 272.9 2 2 1 0.0029 11 0 0 0 - - - - - 4.5154 0.9997 221125_WJC_METTL3_EV_vs_WT_F06.15707.15707.2 0.0835 18-Dec K.YEELQITAGR.H "sp|P04264|K2C1_HUMAN,sp|P04259|K2C6B_HUMAN" 2 1178.5932 999 84632 15707 2 1178.592258 590.3039 "Keratin, type II cytoskeletal 1 OS=Homo sapiens OX=9606 GN=KRT1 PE=1 SV=6" 4.53 2649.6 - 3.38E+06 - - - -0.7585 - 2.295 0.306 - 608.7 1 2 0 -0.0009 10 0 0 0 5.84E+07 0.00E+00 - - - 3.6197 1 221125_WJC_METTL3_EV_vs_WT_F06.15708.15708.4 3.34E-07 20/90 K.GHFGPINSVAFHPDGK[136.11].S "sp|Q13347|EIF3I_HUMAN,tr|A0A7I2YQT9|A0A7I2YQT9_HUMAN,tr|A0A7I2V613|A0A7I2V613_HUMAN,tr|A0A7I2V3N2|A0A7I2V3N2_HUMAN,tr|A0A7I2YQU2|A0A7I2YQU2_HUMAN,tr|A0A7I2YQF8|A0A7I2YQF8_HUMAN,tr|A0A7I2V3U3|A0A7I2V3U3_HUMAN,tr|A0A7I2V607|A0A7I2V607_HUMAN,tr|A0A7I2V640|A0A7I2V640_HUMAN,tr|A0A7P0MRT9|A0A7P0MRT9_HUMAN,tr|A0A7I2V5V8|A0A7I2V5V8_HUMAN,tr|A0A7I2V2M3|A0A7I2V2M3_HUMAN,tr|A0A7I2V4C2|A0A7I2V4C2_HUMAN,tr|A0A7I2YQI2|A0A7I2YQI2_HUMAN,tr|A0A7I2YQC8|A0A7I2YQC8_HUMAN,tr|A0A7I2V685|A0A7I2V685_HUMAN" 16 1686.8358 1.08 84633 15708 4 1686.834953 422.7162 Eukaryotic translation initiation factor 3 subunit I OS=Homo sapiens OX=9606 GN=EIF3I PE=1 SV=1 6.92 2649.6 - 2.37E+06 - - - -0.4956 - 3.451 0.526 - 476.5 1 2 0 -0.0008 16 0 0 0 3.79E+07 3.52E+07 - - - 4.2404 0.9789 221125_WJC_METTL3_EV_vs_WT_F06.15709.15709.3 0.0775 17/36 L.PTSLTIHHPR.E sp|Q02413|DSG1_HUMAN 1 1157.6305 13.22 84634 15709 3 1157.633643 386.8841 Desmoglein-1 OS=Homo sapiens OX=9606 GN=DSG1 PE=1 SV=2 10.18 2649.7 - 758607 - - - 2.6796 - 2.759 0.367 - 474.9 1 1 0 0.0031 10 0 0 0 1.18E+07 8.96E+05 - - - 5.5947 0.9757 221125_WJC_METTL3_EV_vs_WT_F06.15711.15711.3 0.00394 Dec-60 K.WQPGEEPAGSVVQDSR[166.11].L "sp|Q9Y5K5|UCHL5_HUMAN,tr|Q5LJA9|Q5LJA9_HUMAN,tr|Q5LJB0|Q5LJB0_HUMAN,tr|Q5LJA5|Q5LJA5_HUMAN" 4 1750.815 0.5 84636 15711 3 1750.804298 584.6123 Ubiquitin carboxyl-terminal hydrolase isozyme L5 OS=Homo sapiens OX=9606 GN=UCHL5 PE=1 SV=3 4.14 2650 - 725335 - - - -6.1109 - 1.991 0.292 - 161.3 1 2 0 -0.0107 16 0 0 0 4.14E+06 8.32E+06 - - - 3.5595 0.9977 221125_WJC_METTL3_EV_vs_WT_F06.15713.15713.2 1.07E-06 24-Nov K.AQHPDYSFGELSR.L "sp|Q86U86|PB1_HUMAN,tr|E7EVG2|E7EVG2_HUMAN" 2 1505.6899 2.29 84638 15713 2 1505.696887 753.8522 Protein polybromo-1 OS=Homo sapiens OX=9606 GN=PBRM1 PE=1 SV=1 5.32 2650.2 - 569300 - - - 4.6364 - 1.943 0.504 - 305.7 1 2 0 0.007 13 0 0 0 8.32E+06 3.63E+06 - - - 4.4661 1 221125_WJC_METTL3_EV_vs_WT_F06.15714.15714.2 3.00E-09 17/34 K.GINSSNVENQLQATQAAR[166.11].K "sp|P52292|IMA1_HUMAN,tr|J3QLL0|J3QLL0_HUMAN,tr|J3KS65|J3KS65_HUMAN,tr|A0A7I2V3Z3|A0A7I2V3Z3_HUMAN,tr|A0A7I2YQE1|A0A7I2YQE1_HUMAN,tr|A0A7I2V487|A0A7I2V487_HUMAN,tr|A0A7I2V351|A0A7I2V351_HUMAN" 7 1909.9481 1.24 84639 15714 2 1909.949885 955.9813 Importin subunit alpha-1 OS=Homo sapiens OX=9606 GN=KPNA2 PE=1 SV=1 6 2650.4 - 568403 - - - 0.9157 - 3.741 0.62 - 933.4 1 2 0 0.0017 18 0 0 0 9.36E+07 7.56E+07 - - - 6.8635 1 221125_WJC_METTL3_EV_vs_WT_F06.15718.15718.3 6.71E-08 14/48 K.AQHPDYSFGELSR[166.11].L "sp|Q86U86|PB1_HUMAN,tr|E7EVG2|E7EVG2_HUMAN" 2 1515.6982 1.65 84641 15718 3 1515.698072 506.24 Protein polybromo-1 OS=Homo sapiens OX=9606 GN=PBRM1 PE=1 SV=1 5.32 2650.9 - 6.43E+06 - - - -0.0686 - 2.385 0.6 - 219.9 1 2 0 -0.0001 13 0 0 0 1.45E+08 8.74E+07 - - - 7.586 1 221125_WJC_METTL3_EV_vs_WT_F06.15719.15719.3 3.30E-06 Dec-68 K.GINSSNVENQLQATQAAR.K "sp|P52292|IMA1_HUMAN,tr|J3QLL0|J3QLL0_HUMAN,tr|J3KS65|J3KS65_HUMAN,tr|A0A7I2V3Z3|A0A7I2V3Z3_HUMAN,tr|A0A7I2YQE1|A0A7I2YQE1_HUMAN,tr|A0A7I2V487|A0A7I2V487_HUMAN,tr|A0A7I2V351|A0A7I2V351_HUMAN" 7 1899.9399 1.23 84642 15719 3 1899.942868 634.3206 Importin subunit alpha-1 OS=Homo sapiens OX=9606 GN=KPNA2 PE=1 SV=1 6 2650.9 - 3.65E+06 - - - 1.5801 - 2.438 0.533 - 138.6 1 2 0 0.003 18 0 0 0 2.07E+08 1.69E+08 - - - 6.7007 1 221125_WJC_METTL3_EV_vs_WT_F06.15721.15721.3 3.48E-06 14/60 R.MTQNPNYYNLQGISHR[166.11].H sp|O75643|U520_HUMAN 1 1944.914 1.9 84644 15721 3 1944.912723 649.3119 U5 small nuclear ribonucleoprotein 200 kDa helicase OS=Homo sapiens OX=9606 GN=SNRNP200 PE=1 SV=2 8.36 2651 - 2.83E+06 - - - -0.6561 - 2.913 0.553 - 236.8 1 2 0 -0.0013 16 0 0 0 7.35E+07 3.88E+07 - - - 7.4484 1 221125_WJC_METTL3_EV_vs_WT_F06.15722.15722.2 1.30E-14 23/34 K.GINSSNVENQLQATQAAR.K "sp|P52292|IMA1_HUMAN,tr|J3QLL0|J3QLL0_HUMAN,tr|J3KS65|J3KS65_HUMAN,tr|A0A7I2V3Z3|A0A7I2V3Z3_HUMAN,tr|A0A7I2YQE1|A0A7I2YQE1_HUMAN,tr|A0A7I2V487|A0A7I2V487_HUMAN,tr|A0A7I2V351|A0A7I2V351_HUMAN" 7 1899.9399 1.24 84645 15722 2 1899.942638 950.9772 Importin subunit alpha-1 OS=Homo sapiens OX=9606 GN=KPNA2 PE=1 SV=1 6 2651.2 - 1.49E+06 - - - 1.459 - 4.279 0.71 - 1633.5 1 2 0 0.0028 18 0 0 0 9.36E+07 7.56E+07 - - - 7.8582 0.9998 221125_WJC_METTL3_EV_vs_WT_F06.15723.15723.4 1.45E-05 17/72 K.LK[136.11]EIFMQVEDER[166.11]R[166.11].H sp|P35580|MYH10_HUMAN 1 1719.8972 1.01 84646 15723 4 1719.897847 430.9816 Myosin-10 OS=Homo sapiens OX=9606 GN=MYH10 PE=1 SV=3 4.87 2651.3 - 1.32E+06 - - - 0.3587 - 3.019 0.448 - 287.7 1 2 1 0.0006 13 0 0 0 1.77E+07 1.75E+07 - - - 3.5349 0.995 221125_WJC_METTL3_EV_vs_WT_F06.15725.15725.4 0.0975 15/96 K.LFGLEPGRPPPTGPEHK.W "sp|O15417|TNC18_HUMAN,tr|H9KVB4|H9KVB4_HUMAN" 2 1827.9632 2.26 84648 15725 4 1827.964192 457.9981 Trinucleotide repeat-containing gene 18 protein OS=Homo sapiens OX=9606 GN=TNRC18 PE=1 SV=3 6.76 2651.5 - 1.07E+06 - - - 0.5602 - 2.417 0.217 - 170.8 1 2 0 0.001 17 0 0 0 2.06E+07 9.10E+06 - - - 1.4209 1 221125_WJC_METTL3_EV_vs_WT_F06.15726.15726.3 2.21E-13 27/76 K.LLNGPGDVETGTSITVPQK[136.11]K[136.11].W "sp|Q9HC07|TM165_HUMAN,tr|V9GY93|V9GY93_HUMAN" 2 2069.1339 1.14 84649 15726 3 2069.139751 690.7186 Transmembrane protein 165 OS=Homo sapiens OX=9606 GN=TMEM165 PE=1 SV=1 6.07 2651.6 - 640140 - - - 2.8108 - 3.872 0.705 - 632 1 2 0 0.0058 20 0 0 0 1.68E+08 1.47E+08 - - - 9.6827 1 221125_WJC_METTL3_EV_vs_WT_F06.15728.15728.3 1.55E-05 26/68 R.ALQDLENAASGDAAVHQR.L "sp|Q96P16|RPR1A_HUMAN,tr|A0A0C4DGQ6|A0A0C4DGQ6_HUMAN,tr|K7EP82|K7EP82_HUMAN" 3 1864.9028 1.74 84650 15728 3 1864.905601 622.6415 Regulation of nuclear pre-mRNA domain-containing protein 1A OS=Homo sapiens OX=9606 GN=RPRD1A PE=1 SV=1 4.54 2651.8 - 6.47E+06 - - - 1.5272 - 4.126 0.588 - 1060.1 1 2 0 0.0028 18 0 0 0 9.16E+07 5.27E+07 - - - 8.6241 1 221125_WJC_METTL3_EV_vs_WT_F06.15730.15730.3 3.48E-10 23/68 R.ALQDLENAASGDAAVHQR[166.11].L "sp|Q96P16|RPR1A_HUMAN,tr|A0A0C4DGQ6|A0A0C4DGQ6_HUMAN,tr|K7EP82|K7EP82_HUMAN" 3 1874.911 1.84 84652 15730 3 1874.913637 625.9776 Regulation of nuclear pre-mRNA domain-containing protein 1A OS=Homo sapiens OX=9606 GN=RPRD1A PE=1 SV=1 4.54 2651.9 - 4.35E+06 - - - 1.3942 - 3.458 0.63 - 812.7 1 2 0 0.0026 18 0 0 0 9.68E+07 5.27E+07 - - - 8.6526 0.9999 221125_WJC_METTL3_EV_vs_WT_F06.15731.15731.3 5.79E-05 13/60 R.DAINQGMDEELERDEK.V "sp|P11177|ODPB_HUMAN,tr|F8WF02|F8WF02_HUMAN,tr|C9J634|C9J634_HUMAN" 3 1890.8265 0.7 84653 15731 3 1890.82803 631.2828 "Pyruvate dehydrogenase E1 component subunit beta, mitochondrial OS=Homo sapiens OX=9606 GN=PDHB PE=1 SV=3" 3.95 2652 - 2.54E+06 - - - 0.7901 - 2.735 0.525 - 229.8 1 2 1 0.0015 16 0 0 0 2.28E+07 3.23E+07 - - - 6.9744 1 221125_WJC_METTL3_EV_vs_WT_F06.15732.15732.3 4.09E-08 13/56 K.HNEETGDNVGPLIIK[136.11].K sp|Q9NZ45|CISD1_HUMAN 1 1642.8406 1.59 84654 15732 3 1642.839365 548.6208 CDGSH iron-sulfur domain-containing protein 1 OS=Homo sapiens OX=9606 GN=CISD1 PE=1 SV=1 4.65 2652 - 1.92E+06 - - - -0.7517 - 2.512 0.533 - 279.5 1 2 0 -0.0012 15 0 0 0 1.35E+08 8.49E+07 - - - 6.8855 0.9997 221125_WJC_METTL3_EV_vs_WT_F06.15733.15733.3 5.98E-07 15/44 R.NK[136.11]IAGYVTHLMK[136.11].R "sp|P08708|RS17_HUMAN,tr|H3BNC9|H3BNC9_HUMAN,tr|H0YN88|H0YN88_HUMAN,tr|A0A075B716|A0A075B716_HUMAN" 4 1389.7773 0.94 84655 15733 3 1389.776741 464.2664 40S ribosomal protein S17 OS=Homo sapiens OX=9606 GN=RPS17 PE=1 SV=2 9.7 2652.1 - 917917 - - - -0.4317 - 2.798 0.38 - 284.6 1 2 1 -0.0006 12 0 0 0 6.64E+06 7.05E+06 - - - 5.6284 1 221125_WJC_METTL3_EV_vs_WT_F06.15734.15734.2 1.90E-11 19/36 K.SPMVEQAVQTGSADNLNAK[136.11].K "sp|Q9BX40|LS14B_HUMAN,tr|Q5TBP9|Q5TBP9_HUMAN,tr|Q5TBQ1|Q5TBQ1_HUMAN,tr|Q5TBQ0|Q5TBQ0_HUMAN" 4 1966.951 0.84 84656 15734 2 1966.948734 984.4828 Protein LSM14 homolog B OS=Homo sapiens OX=9606 GN=LSM14B PE=1 SV=1 4.37 2652.3 - 747723 - - - -1.1292 - 4.156 0.662 - 1145.8 1 2 0 -0.0022 19 0 0 0 9.80E+06 1.16E+07 - - - 7.4322 1 221125_WJC_METTL3_EV_vs_WT_F06.15740.15740.3 1.79E-07 20/72 K.SPMVEQAVQTGSADNLNAK[136.11].K "sp|Q9BX40|LS14B_HUMAN,tr|Q5TBP9|Q5TBP9_HUMAN,tr|Q5TBQ1|Q5TBQ1_HUMAN,tr|Q5TBQ0|Q5TBQ0_HUMAN" 4 1966.951 0.96 84660 15740 3 1966.949907 656.6576 Protein LSM14 homolog B OS=Homo sapiens OX=9606 GN=LSM14B PE=1 SV=1 4.37 2652.9 - 3.03E+06 - - - -0.5328 - 3.783 0.582 - 769.6 1 2 0 -0.001 19 0 0 0 4.18E+07 4.35E+07 - - - 8.2973 1 221125_WJC_METTL3_EV_vs_WT_F06.15742.15742.3 1.86E-07 14/68 K.GINSSNVENQLQATQAAR[166.11].K "sp|P52292|IMA1_HUMAN,tr|J3QLL0|J3QLL0_HUMAN,tr|J3KS65|J3KS65_HUMAN,tr|A0A7I2V3Z3|A0A7I2V3Z3_HUMAN,tr|A0A7I2YQE1|A0A7I2YQE1_HUMAN,tr|A0A7I2V487|A0A7I2V487_HUMAN,tr|A0A7I2V351|A0A7I2V351_HUMAN" 7 1909.9481 1.23 84662 15742 3 1909.947919 637.6567 Importin subunit alpha-1 OS=Homo sapiens OX=9606 GN=KPNA2 PE=1 SV=1 6 2653.1 - 9.32E+06 - - - -0.1136 - 2.414 0.497 - 237.7 1 2 0 -0.0002 18 0 0 0 2.07E+08 1.69E+08 - - - 6.2755 1 221125_WJC_METTL3_EV_vs_WT_F06.15743.15743.3 2.75E-11 19/76 K.LLNGPGDVETGTSITVPQKK.W "sp|Q9HC07|TM165_HUMAN,tr|V9GY93|V9GY93_HUMAN" 2 2053.1055 1.14 84663 15743 3 2053.109272 685.3758 Transmembrane protein 165 OS=Homo sapiens OX=9606 GN=TMEM165 PE=1 SV=1 6.07 2653.1 - 1.71E+06 - - - 1.8202 - 3.893 0.69 - 264.3 1 2 0 0.0037 20 0 0 0 1.68E+08 1.47E+08 - - - 9.5292 0.9993 221125_WJC_METTL3_EV_vs_WT_F06.15745.15745.3 0.000874 Dec-56 R.GQPLPDHLQMAVQGK[136.11].R "sp|P51532|SMCA4_HUMAN,tr|A0A2R8Y7S2|A0A2R8Y7S2_HUMAN,tr|Q9HBD4|Q9HBD4_HUMAN,tr|A0A2R8YGP5|A0A2R8YGP5_HUMAN,tr|A0A2R8Y4P4|A0A2R8Y4P4_HUMAN" 5 1625.8439 0.82 84665 15745 3 1625.845021 542.9552 Transcription activator BRG1 OS=Homo sapiens OX=9606 GN=SMARCA4 PE=1 SV=2 6.74 2653.3 - 1.07E+06 - - - 0.6827 - 2.215 0.264 - 155.5 1 2 0 0.0011 15 0 0 0 2.39E+07 2.90E+07 - - - 3.5581 0.9999 221125_WJC_METTL3_EV_vs_WT_F06.15751.15751.2 5.76E-05 22-Nov K.TEELEEESFPER.S "sp|Q9Y2W1|TR150_HUMAN,tr|A0A3B3ITZ9|A0A3B3ITZ9_HUMAN" 2 1493.6522 4.19 84669 15751 2 1493.652891 747.8334 Thyroid hormone receptor-associated protein 3 OS=Homo sapiens OX=9606 GN=THRAP3 PE=1 SV=2 3.9 2654 - 744830 - - - 0.474 - 2.516 0.566 - 501.5 1 2 0 0.0007 12 0 0 0 2.80E+07 6.69E+06 - - - 5.649 0.9997 221125_WJC_METTL3_EV_vs_WT_F06.15753.15753.3 2.08E-07 Dec-48 R.FTENDKEYQEYLK.R "sp|Q9BTL3|RAMAC_HUMAN,tr|A0A3B3IU46|A0A3B3IU46_HUMAN" 2 1705.7835 1.24 84671 15753 3 1705.788016 569.6018 RNA guanine-N7 methyltransferase activating subunit OS=Homo sapiens OX=9606 GN=RAMAC PE=1 SV=1 4.41 2654.3 - 827677 - - - 2.6287 - 2.425 0.525 - 84.6 1 2 1 0.0045 13 0 0 0 1.37E+08 1.11E+08 - - - 6.7937 0.9998 221125_WJC_METTL3_EV_vs_WT_F06.15758.15758.2 2.42E-06 30-Nov K.WQPGEEPAGSVVQDSR[166.11].L "sp|Q9Y5K5|UCHL5_HUMAN,tr|Q5LJA9|Q5LJA9_HUMAN,tr|Q5LJB0|Q5LJB0_HUMAN,tr|Q5LJA5|Q5LJA5_HUMAN" 4 1750.815 2.47 84676 15758 2 1750.81327 876.4148 Ubiquitin carboxyl-terminal hydrolase isozyme L5 OS=Homo sapiens OX=9606 GN=UCHL5 PE=1 SV=3 4.14 2654.9 - 376648 - - - -0.9864 - 1.955 0.521 - 250.4 1 2 0 -0.0017 16 0 0 0 1.25E+07 5.05E+06 - - - 4.5367 1 221125_WJC_METTL3_EV_vs_WT_F06.15759.15759.3 0.000723 14/48 R.IVNVSSLAHHLGR.L "sp|Q8TC12|RDH11_HUMAN,tr|G3V234|G3V234_HUMAN,tr|H0YIZ8|H0YIZ8_HUMAN,tr|G3V2G6|G3V2G6_HUMAN,tr|H0YJ46|H0YJ46_HUMAN" 5 1401.7841 1.08 84677 15759 3 1401.783905 468.2686 Retinol dehydrogenase 11 OS=Homo sapiens OX=9606 GN=RDH11 PE=1 SV=2 9.76 2655.1 - 313374 - - - -0.1256 - 2.963 0.473 - 263.6 1 2 0 -0.0002 13 0 0 0 3.94E+06 3.65E+06 - - - 6.7584 0.9999 221125_WJC_METTL3_EV_vs_WT_F06.15767.15767.3 2.23E-06 14/48 R.FTENDK[136.11]EYQEYLK[136.11].R "sp|Q9BTL3|RAMAC_HUMAN,tr|A0A3B3IU46|A0A3B3IU46_HUMAN" 2 1721.8119 1.24 84683 15767 3 1721.813011 574.9446 RNA guanine-N7 methyltransferase activating subunit OS=Homo sapiens OX=9606 GN=RAMAC PE=1 SV=1 4.41 2655.8 - 2.19E+06 - - - 0.6267 - 2.604 0.555 - 147.1 1 2 1 0.0011 13 0 0 0 1.37E+08 1.11E+08 - - - 7.3222 0.9998 221125_WJC_METTL3_EV_vs_WT_F06.15768.15768.3 3.63E-05 14/56 R.GQPLPDHLQMAVQGK.R "sp|P51532|SMCA4_HUMAN,tr|A0A2R8Y7S2|A0A2R8Y7S2_HUMAN,tr|Q9HBD4|Q9HBD4_HUMAN,tr|A0A2R8YGP5|A0A2R8YGP5_HUMAN,tr|A0A2R8Y4P4|A0A2R8Y4P4_HUMAN" 5 1617.8297 0.83 84684 15768 3 1617.834362 540.2838 Transcription activator BRG1 OS=Homo sapiens OX=9606 GN=SMARCA4 PE=1 SV=2 6.74 2655.9 - 1.66E+06 - - - 2.8748 - 2.927 0.407 - 261.1 1 2 0 0.0047 15 0 0 0 2.39E+07 2.88E+07 - - - 5.8788 1 221125_WJC_METTL3_EV_vs_WT_F06.15778.15778.2 3.94E-12 21/38 R.GGGGSGGYYGQGGMSGGGWR.G sp|P31942|HNRH3_HUMAN 1 1803.7383 2.06 84692 15778 2 1803.74203 902.8764 Heterogeneous nuclear ribonucleoprotein H3 OS=Homo sapiens OX=9606 GN=HNRNPH3 PE=1 SV=2 8.59 2657.2 - 500227 - - - 2.0513 - 3.493 0.767 - 1145.4 1 2 0 0.0037 20 0 0 0 5.56E+06 2.70E+06 - - - 7.78 0.9996 221125_WJC_METTL3_EV_vs_WT_F06.15782.15782.2 0.00114 26-Oct K.DNGIR[166.11]PSSLEQMAK[136.11].L "sp|P55084|ECHB_HUMAN,tr|F5GZQ3|F5GZQ3_HUMAN,tr|B5MD38|B5MD38_HUMAN" 3 1562.7842 0.001 84696 15782 2 1562.782798 782.3994 "Trifunctional enzyme subunit beta, mitochondrial OS=Homo sapiens OX=9606 GN=HADHB PE=1 SV=3" 6.07 2657.7 - 211697 - - - -0.8722 - 1.969 0.35 - 187.1 1 2 0 -0.0014 14 0 0 0 0.00E+00 4.87E+06 - - - 3.3259 1 221125_WJC_METTL3_EV_vs_WT_F06.15784.15784.3 9.01E-10 17/56 K.HNEETGDNVGPLIIK.K sp|Q9NZ45|CISD1_HUMAN 1 1634.8264 1.58 84697 15784 3 1634.828123 545.9494 CDGSH iron-sulfur domain-containing protein 1 OS=Homo sapiens OX=9606 GN=CISD1 PE=1 SV=1 4.65 2657.9 - 8.17E+06 - - - 1.0539 - 3.001 0.629 - 439.1 1 2 0 0.0017 15 0 0 0 1.35E+08 8.52E+07 - - - 8.4198 0.8984 221125_WJC_METTL3_EV_vs_WT_F06.15787.15787.3 3.81E-09 19/88 A.SRQSSGPGASSGTSGDHGELVVR.L "tr|E9PN91|E9PN91_HUMAN,tr|E9PL71|E9PL71_HUMAN" 2 2227.0577 999 84699 15787 3 2227.046007 743.3599 Elongation factor 1-delta OS=Homo sapiens OX=9606 GN=EEF1D PE=1 SV=1 6.47 2658.2 - 703254 - - - -5.2729 - 4.112 0.544 - 288.1 1 1 1 -0.0117 23 0 0 0 7.30E+06 0.00E+00 - - - 7.9188 1 221125_WJC_METTL3_EV_vs_WT_F06.15788.15788.3 8.40E-07 14/64 K.SFEAPATINSASLHPEK[136.11].E sp|Q9Y3F4|STRAP_HUMAN 1 1805.9039 1.57 84700 15788 3 1805.904701 602.9753 Serine-threonine kinase receptor-associated protein OS=Homo sapiens OX=9606 GN=STRAP PE=1 SV=1 5.38 2658.3 - 3.22E+06 - - - 0.428 - 2.784 0.564 - 135.8 1 2 0 0.0008 17 0 0 0 9.28E+07 5.93E+07 - - - 7.4145 0.9988 221125_WJC_METTL3_EV_vs_WT_F06.15789.15789.3 0.000938 Oct-56 K.ITSYFLNEGSQARPR.S sp|O75792|RNH2A_HUMAN 1 1737.8798 2.04 84701 15789 3 1737.88321 580.3006 Ribonuclease H2 subunit A OS=Homo sapiens OX=9606 GN=RNASEH2A PE=1 SV=2 8.75 2658.4 - 760578 - - - 1.9437 - 2.089 0.285 - 145.2 1 2 0 0.0034 15 0 0 0 6.85E+06 3.36E+06 - - - 3.6388 0.9719 221125_WJC_METTL3_EV_vs_WT_F06.15790.15790.3 0.14 Sep-56 K.ITSYFLNEGSQAR[166.11]PR[166.11].S sp|O75792|RNH2A_HUMAN 1 1757.8964 3.44 84702 15790 3 1757.901008 586.9727 Ribonuclease H2 subunit A OS=Homo sapiens OX=9606 GN=RNASEH2A PE=1 SV=2 8.75 2658.5 - 480094 - - - 2.6372 - 1.94 0.14 - 76.4 1 2 0 0.0046 15 0 0 0 1.15E+07 3.36E+06 - - - 1.8288 1 221125_WJC_METTL3_EV_vs_WT_F06.15793.15793.2 1.87E-06 24-Dec R.FTENDK[136.11]EYQEYLK[136.11].R "sp|Q9BTL3|RAMAC_HUMAN,tr|A0A3B3IU46|A0A3B3IU46_HUMAN" 2 1721.8119 1.21 84705 15793 2 1721.815344 861.9132 RNA guanine-N7 methyltransferase activating subunit OS=Homo sapiens OX=9606 GN=RAMAC PE=1 SV=1 4.41 2658.9 - 371179 - - - 1.9816 - 2.85 0.624 - 446.2 1 2 1 0.0034 13 0 0 0 6.77E+06 5.59E+06 - - - 6.3368 0.9836 221125_WJC_METTL3_EV_vs_WT_F06.15800.15800.3 7.00E-05 15/44 L.RMSVEADINGLR.R "sp|P02533|K1C14_HUMAN,sp|P08727|K1C19_HUMAN,tr|C9JM50|C9JM50_HUMAN" 3 1359.6929 17.11 84710 15800 3 1359.688512 454.2382 "Keratin, type I cytoskeletal 14 OS=Homo sapiens OX=9606 GN=KRT14 PE=1 SV=4" 6.07 2659.7 - 1.00E+06 - - - -3.2147 - 2.645 0.452 - 452.6 1 1 0 -0.0044 12 0 0 0 7.12E+06 4.16E+05 - - - 6.2742 1 221125_WJC_METTL3_EV_vs_WT_F06.15801.15801.2 1.67E-07 13/28 K.HNEETGDNVGPLIIK.K sp|Q9NZ45|CISD1_HUMAN 1 1634.8264 1.72 84711 15801 2 1634.826775 818.4205 CDGSH iron-sulfur domain-containing protein 1 OS=Homo sapiens OX=9606 GN=CISD1 PE=1 SV=1 4.65 2659.9 - 718400 - - - 0.2294 - 3.253 0.638 - 437.8 1 2 0 0.0004 15 0 0 0 1.44E+07 8.40E+06 - - - 6.6532 0.9998 221125_WJC_METTL3_EV_vs_WT_F06.15802.15802.3 1.80E-05 13/40 K.TTLLHMLKDDR.L "sp|Q9NR31|SAR1A_HUMAN,sp|Q9Y6B6|SAR1B_HUMAN,tr|D6RAA2|D6RAA2_HUMAN,tr|D6RD69|D6RD69_HUMAN,tr|X1WI22|X1WI22_HUMAN,tr|Q5SQT8|Q5SQT8_HUMAN,tr|D6RDB2|D6RDB2_HUMAN" 7 1341.7075 1.07 84712 15802 3 1341.708569 448.2431 GTP-binding protein SAR1a OS=Homo sapiens OX=9606 GN=SAR1A PE=1 SV=1 6.41 2660 - 443074 - - - 0.8184 - 2.406 0.445 - 279.7 1 2 1 0.0011 11 0 0 0 4.24E+08 3.95E+08 - - - 5.9952 1 221125_WJC_METTL3_EV_vs_WT_F06.15808.15808.3 2.56E-09 16/36 K.DHHFDMINIK.S sp|Q9P032|NDUF4_HUMAN 1 1268.5972 1.36 84716 15808 3 1268.597489 423.873 NADH dehydrogenase [ubiquinone] 1 alpha subcomplex assembly factor 4 OS=Homo sapiens OX=9606 GN=NDUFAF4 PE=1 SV=1 5.98 2660.8 - 1.81E+06 - - - 0.2341 - 3.345 0.637 - 521.3 1 2 0 0.0003 10 0 0 0 1.20E+08 8.86E+07 - - - 9.1682 1 221125_WJC_METTL3_EV_vs_WT_F06.15809.15809.3 6.36E-10 16/68 K.YVHYEIDAC[160.03]MDSEAPGSK[136.11].D "sp|Q86U44|MTA70_HUMAN,tr|H0YFV6|H0YFV6_HUMAN" 2 2078.8805 0.001 84717 15809 3 2079.880291 693.9674 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 4.31 2660.9 - 1.54E+06 - - - 480.9314 - 3.454 0.67 - 281 1 2 0 0.9998 18 0 0 0 0.00E+00 5.05E+07 - - - 8.8195 0.9998 221125_WJC_METTL3_EV_vs_WT_F06.15811.15811.3 2.83E-07 19/44 K.VKELEEELQHLK.Q "sp|P82094|TMF1_HUMAN,tr|F8WF45|F8WF45_HUMAN,tr|A0A2R8Y7M0|A0A2R8Y7M0_HUMAN" 3 1493.809 1.56 84719 15811 3 1493.813304 498.9436 TATA element modulatory factor OS=Homo sapiens OX=9606 GN=TMF1 PE=1 SV=2 4.91 2661 - 1.36E+06 - - - 2.9087 - 3.207 0.529 - 352.2 1 2 1 0.0043 12 0 0 0 8.99E+07 5.77E+07 - - - 7.6668 1 221125_WJC_METTL3_EV_vs_WT_F06.15813.15813.2 2.48E-11 14/24 R.FTENDKEYQEYLK.R "sp|Q9BTL3|RAMAC_HUMAN,tr|A0A3B3IU46|A0A3B3IU46_HUMAN" 2 1705.7835 1.21 84721 15813 2 1705.78384 853.899 RNA guanine-N7 methyltransferase activating subunit OS=Homo sapiens OX=9606 GN=RAMAC PE=1 SV=1 4.41 2661.2 - 607096 - - - 0.1806 - 3.212 0.673 - 659.5 1 2 1 0.0003 13 0 0 0 6.77E+06 5.59E+06 - - - 7.0065 0.9999 221125_WJC_METTL3_EV_vs_WT_F06.15814.15814.2 2.84E-07 13/28 K.HNEETGDNVGPLIIK[136.11].K sp|Q9NZ45|CISD1_HUMAN 1 1642.8406 1.83 84722 15814 2 1642.840801 822.4276 CDGSH iron-sulfur domain-containing protein 1 OS=Homo sapiens OX=9606 GN=CISD1 PE=1 SV=1 4.65 2661.4 - 568261 - - - 0.1223 - 2.937 0.466 - 444 1 2 0 0.0002 15 0 0 0 1.41E+07 7.73E+06 - - - 5.1316 0.9999 221125_WJC_METTL3_EV_vs_WT_F06.15815.15815.2 2.70E-07 28-Dec K.DQTKPTPLILDEQGR.T sp|O43395|PRPF3_HUMAN 1 1709.8948 3.45 84723 15815 2 1709.893963 855.9547 U4\U6 small nuclear ribonucleoprotein Prp3 OS=Homo sapiens OX=9606 GN=PRPF3 PE=1 SV=2 4.56 2661.5 - 437982 - - - -0.4977 - 2.403 0.588 - 227.5 1 2 0 -0.0008 15 0 0 0 4.77E+07 1.38E+07 - - - 5.5392 1 221125_WJC_METTL3_EV_vs_WT_F06.15823.15823.3 3.08E-08 18/60 R.RVTFEADENENITVVK.G "sp|Q9NX63|MIC19_HUMAN,tr|F8WAR4|F8WAR4_HUMAN,tr|C9JRZ6|C9JRZ6_HUMAN" 3 1862.9374 2.24 84729 15823 3 1862.937205 621.9864 MICOS complex subunit MIC19 OS=Homo sapiens OX=9606 GN=CHCHD3 PE=1 SV=1 4.41 2662.4 - 8.72E+06 - - - -0.1084 - 3.592 0.652 - 516 1 2 0 -0.0002 16 0 0 0 1.44E+08 6.44E+07 - - - 9.0901 1 221125_WJC_METTL3_EV_vs_WT_F06.15825.15825.3 1.68E-10 15/36 K.DHHFDMINIK[136.11].S sp|Q9P032|NDUF4_HUMAN 1 1276.6114 1.36 84731 15825 3 1276.611521 426.5444 NADH dehydrogenase [ubiquinone] 1 alpha subcomplex assembly factor 4 OS=Homo sapiens OX=9606 GN=NDUFAF4 PE=1 SV=1 5.98 2662.5 - 4.46E+06 - - - 0.101 - 2.954 0.658 - 429.8 1 2 0 0.0001 10 0 0 0 1.20E+08 8.86E+07 - - - 9.0393 0.9998 221125_WJC_METTL3_EV_vs_WT_F06.15826.15826.3 1.73E-05 13/44 K.VK[136.11]ELEEELQHLK[136.11].Q "sp|P82094|TMF1_HUMAN,tr|F8WF45|F8WF45_HUMAN,tr|A0A2R8Y7M0|A0A2R8Y7M0_HUMAN" 3 1509.8374 1.56 84732 15826 3 1509.838959 504.2864 TATA element modulatory factor OS=Homo sapiens OX=9606 GN=TMF1 PE=1 SV=2 4.91 2662.6 - 2.84E+06 - - - 1.0597 - 2.34 0.49 - 154.6 1 2 1 0.0016 12 0 0 0 8.99E+07 5.77E+07 - - - 6.3591 0.9998 221125_WJC_METTL3_EV_vs_WT_F06.15828.15828.3 1.15E-05 Dec-56 K.NK[136.11]QPVTDPLLTPVEK[136.11].A "sp|Q9BVJ6|UT14A_HUMAN,tr|X6RJY0|X6RJY0_HUMAN" 2 1693.9585 2.03 84734 15828 3 1693.959464 565.6601 U3 small nucleolar RNA-associated protein 14 homolog A OS=Homo sapiens OX=9606 GN=UTP14A PE=1 SV=1 6.07 2662.7 - 1.32E+06 - - - 0.5472 - 2.368 0.476 - 145.2 1 2 1 0.0009 15 0 0 0 4.40E+07 2.17E+07 - - - 6.0961 1 221125_WJC_METTL3_EV_vs_WT_F06.15834.15834.3 3.90E-05 13/40 R.DYTQYYDHISK[136.11].Q "sp|O75794|CD123_HUMAN,tr|X6RF82|X6RF82_HUMAN,tr|H7BZW7|H7BZW7_HUMAN" 3 1439.6449 1.25 84738 15834 3 1439.643533 480.8889 Cell division cycle protein 123 homolog OS=Homo sapiens OX=9606 GN=CDC123 PE=1 SV=1 5.21 2663.4 - 1.78E+06 - - - -0.9218 - 2.009 0.542 - 181.2 1 2 0 -0.0013 11 0 0 0 2.15E+07 1.73E+07 - - - 6.5643 0.9981 221125_WJC_METTL3_EV_vs_WT_F06.15835.15835.3 0.000575 14/60 R.LQEGDK[136.11]ILSVNGQDLK[136.11].N "sp|P57105|SYJ2B_HUMAN,tr|A0A087X1F5|A0A087X1F5_HUMAN,tr|A0A087WYV9|A0A087WYV9_HUMAN" 3 1771.9651 1.62 84739 15835 3 1771.964287 591.6623 Synaptojanin-2-binding protein OS=Homo sapiens OX=9606 GN=SYNJ2BP PE=1 SV=2 4.56 2663.5 - 1.39E+06 - - - -0.447 - 2.453 0.28 - 207.9 1 2 1 -0.0008 16 0 0 0 5.42E+07 3.34E+07 - - - 3.9639 0.9998 221125_WJC_METTL3_EV_vs_WT_F06.15836.15836.3 3.50E-05 17/60 R.LQEGDKILSVNGQDLK.N "sp|P57105|SYJ2B_HUMAN,tr|A0A087X1F5|A0A087X1F5_HUMAN,tr|A0A087WYV9|A0A087WYV9_HUMAN" 3 1755.9367 1.64 84740 15836 3 1755.933809 586.3195 Synaptojanin-2-binding protein OS=Homo sapiens OX=9606 GN=SYNJ2BP PE=1 SV=2 4.56 2663.6 - 1.36E+06 - - - -1.6345 - 2.756 0.482 - 368.4 1 2 1 -0.0029 16 0 0 0 5.49E+07 3.34E+07 - - - 6.5143 0.9998 221125_WJC_METTL3_EV_vs_WT_F06.15839.15839.3 0.00116 15/44 R.QTVQVIQQALHR.Q "sp|Q8IXK0|PHC2_HUMAN,tr|A0A0A0MSI2|A0A0A0MSI2_HUMAN" 2 1419.7946 2.23 84743 15839 3 1419.794661 474.2722 Polyhomeotic-like protein 2 OS=Homo sapiens OX=9606 GN=PHC2 PE=1 SV=1 9.76 2663.9 - 701522 - - - 0.0106 - 2.363 0.338 - 313.2 1 2 0 0 12 0 0 0 9.94E+06 4.45E+06 - - - 4.692 0.9999 221125_WJC_METTL3_EV_vs_WT_F06.15841.15841.2 1.01E-06 28-Nov K.DQTK[136.11]PTPLILDEQGR[166.11].T sp|O43395|PRPF3_HUMAN 1 1727.9173 3.43 84745 15841 2 1727.917553 864.9659 U4\U6 small nuclear ribonucleoprotein Prp3 OS=Homo sapiens OX=9606 GN=PRPF3 PE=1 SV=2 4.56 2664.2 - 646435 - - - 0.1557 - 2.11 0.507 - 166.5 1 2 0 0.0003 15 0 0 0 4.74E+07 1.38E+07 - - - 4.6214 0.9999 221125_WJC_METTL3_EV_vs_WT_F06.15843.15843.4 6.82E-05 15/90 R.SVYFKPSLTPSGEFRK.T sp|P49790|NU153_HUMAN 1 1841.9676 1.36 84747 15843 4 1841.968689 461.4992 Nuclear pore complex protein Nup153 OS=Homo sapiens OX=9606 GN=NUP153 PE=1 SV=2 9.7 2664.4 - 367689 - - - 0.5994 - 2.607 0.423 - 109 1 2 0 0.0011 16 0 0 0 5.19E+07 3.83E+07 - - - 3.245 1 221125_WJC_METTL3_EV_vs_WT_F06.15846.15846.3 5.53E-06 15/56 K.DQTK[136.11]PTPLILDEQGR[166.11].T sp|O43395|PRPF3_HUMAN 1 1727.9173 2.78 84749 15846 3 1727.918144 576.9797 U4\U6 small nuclear ribonucleoprotein Prp3 OS=Homo sapiens OX=9606 GN=PRPF3 PE=1 SV=2 4.56 2664.8 - 1.66E+07 - - - 0.4977 - 3.145 0.517 - 328.3 1 2 0 0.0009 15 0 0 0 7.58E+08 2.73E+08 - - - 7.2936 1 221125_WJC_METTL3_EV_vs_WT_F06.15849.15849.3 4.16E-05 13/76 R.FSSC[160.03]GGGGGSFGAGGGFGSR.S sp|P04264|K2C1_HUMAN 1 1764.7274 16002.65 84752 15849 3 1764.726423 589.2498 "Keratin, type II cytoskeletal 1 OS=Homo sapiens OX=9606 GN=KRT1 PE=1 SV=6" 8.25 2664.9 - 4.94E+06 - - - -0.5712 - 2.289 0.55 - 144.1 1 2 0 -0.001 20 0 0 0 2.58E+09 1.61E+05 - - - 6.6807 1 221125_WJC_METTL3_EV_vs_WT_F06.15850.15850.3 0.000237 17/60 K.NQVALNPQNTVFDAK[136.11]R[166.11].L "sp|P0DMV8|HS71A_HUMAN,sp|P0DMV9|HS71B_HUMAN,tr|A0A0G2JIW1|A0A0G2JIW1_HUMAN" 3 1831.966 0.43 84753 15850 3 1831.965123 611.6626 Heat shock 70 kDa protein 1A OS=Homo sapiens OX=9606 GN=HSPA1A PE=1 SV=1 8.75 2665 - 1.80E+06 - - - -0.4596 - 3.231 0.489 - 472.7 1 2 0 -0.0008 16 0 0 0 4.55E+08 1.06E+09 - - - 7.0009 1 221125_WJC_METTL3_EV_vs_WT_F06.15851.15851.3 1.31E-08 17/68 K.EAGELKPEEEITVGPVQK.L sp|P53618|COPB_HUMAN 1 1952.0102 0.65 84754 15851 3 1952.008974 651.6774 Coatomer subunit beta OS=Homo sapiens OX=9606 GN=COPB1 PE=1 SV=3 4.33 2665.1 - 1.80E+06 - - - -0.647 - 2.84 0.49 - 300.9 1 2 0 -0.0013 18 0 0 0 4.61E+07 7.11E+07 - - - 6.6018 0.9872 221125_WJC_METTL3_EV_vs_WT_F06.15852.15852.3 0.427 Aug-40 R.DYTQYYDHISK.Q "sp|O75794|CD123_HUMAN,tr|X6RF82|X6RF82_HUMAN,tr|H7BZW7|H7BZW7_HUMAN" 3 1431.6307 1.26 84755 15852 3 1431.62788 478.2175 Cell division cycle protein 123 homolog OS=Homo sapiens OX=9606 GN=CDC123 PE=1 SV=1 5.21 2665.1 - 1.32E+06 - - - -1.9418 - 1.229 0.257 - 60.1 1 2 0 -0.0028 11 0 0 0 2.26E+07 1.79E+07 - - - 1.9903 1 221125_WJC_METTL3_EV_vs_WT_F06.15853.15853.2 7.85E-14 20/38 K.IGSPSPSPSSLSDSSSSFGK[136.11].G "sp|Q8IXZ3|SP8_HUMAN,tr|A0A087X0Q6|A0A087X0Q6_HUMAN" 2 1917.9047 1.12 84756 15853 2 1917.901994 959.9596 Transcription factor Sp8 OS=Homo sapiens OX=9606 GN=SP8 PE=1 SV=3 5.84 2665.3 - 629624 - - - -1.4193 - 3.434 0.721 - 1019.1 1 2 0 -0.0027 20 0 0 0 1.84E+07 1.64E+07 - - - 7.3986 0.9997 221125_WJC_METTL3_EV_vs_WT_F06.15855.15855.2 8.60E-07 30-Nov R.R[166.11]VTFEADENENITVVK[136.11].G "sp|Q9NX63|MIC19_HUMAN,tr|F8WAR4|F8WAR4_HUMAN,tr|C9JRZ6|C9JRZ6_HUMAN" 3 1880.9599 2.12 84758 15855 2 1880.955174 941.4872 MICOS complex subunit MIC19 OS=Homo sapiens OX=9606 GN=CHCHD3 PE=1 SV=1 4.41 2665.6 - 382280 - - - -2.5003 - 2.546 0.545 - 278.4 1 2 0 -0.0047 16 0 0 0 6.24E+06 2.95E+06 - - - 5.3625 1 221125_WJC_METTL3_EV_vs_WT_F06.15858.15858.3 7.54E-06 14/56 K.DQTKPTPLILDEQGR.T sp|O43395|PRPF3_HUMAN 1 1709.8948 2.79 84760 15858 3 1709.894664 570.9722 U4\U6 small nuclear ribonucleoprotein Prp3 OS=Homo sapiens OX=9606 GN=PRPF3 PE=1 SV=2 4.56 2665.9 - 4.64E+07 - - - -0.0877 - 2.783 0.548 - 246.9 1 2 0 -0.0001 15 0 0 0 7.61E+08 2.73E+08 - - - 7.3204 0.9999 221125_WJC_METTL3_EV_vs_WT_F06.15862.15862.3 0.000115 Nov-60 R.R[166.11]VTFEADENENITVVK[136.11].G "sp|Q9NX63|MIC19_HUMAN,tr|F8WAR4|F8WAR4_HUMAN,tr|C9JRZ6|C9JRZ6_HUMAN" 3 1880.9599 2.24 84763 15862 3 1880.955864 627.9939 MICOS complex subunit MIC19 OS=Homo sapiens OX=9606 GN=CHCHD3 PE=1 SV=1 4.41 2666.2 - 6.87E+06 - - - -2.1335 - 2.522 0.429 - 187.1 1 2 0 -0.004 16 0 0 0 1.44E+08 6.44E+07 - - - 5.6954 0.9999 221125_WJC_METTL3_EV_vs_WT_F06.15863.15863.3 0.00113 18/44 R.HLREYQDLLNVK.M "sp|P08670|VIME_HUMAN,sp|P17661|DESM_HUMAN,sp|Q16352|AINX_HUMAN,sp|P07197|NFM_HUMAN,tr|B0YJC5|B0YJC5_HUMAN,tr|B0YJC4|B0YJC4_HUMAN,tr|E7ESP9|E7ESP9_HUMAN,tr|E7EMV2|E7EMV2_HUMAN" 8 1526.8205 2.19 84764 15863 3 1526.820166 509.9475 Vimentin OS=Homo sapiens OX=9606 GN=VIM PE=1 SV=4 6.75 2666.2 - 4.24E+06 - - - -0.2358 - 2.944 0.446 - 457 1 2 1 -0.0004 12 0 0 0 6.27E+07 2.86E+07 - - - 6.5053 0.9993 221125_WJC_METTL3_EV_vs_WT_F06.15866.15866.4 0.0093 15/90 R.SVYFK[136.11]PSLTPSGEFR[166.11]K[136.11].T sp|P49790|NU153_HUMAN 1 1868.0043 1.49 84767 15866 4 1868.002848 468.0083 Nuclear pore complex protein Nup153 OS=Homo sapiens OX=9606 GN=NUP153 PE=1 SV=2 9.7 2666.4 - 1.98E+06 - - - -0.7532 - 2.16 0.308 - 97.7 1 2 0 -0.0014 16 0 0 0 5.75E+07 3.85E+07 - - - 2.1777 0.9999 221125_WJC_METTL3_EV_vs_WT_F06.15867.15867.3 0.000235 14/36 K.QNR[166.11]PIPQWIR[166.11].M "sp|P62891|RL39_HUMAN,sp|Q59GN2|R39L5_HUMAN" 2 1326.7424 0.74 84768 15867 3 1326.740445 443.2547 60S ribosomal protein L39 OS=Homo sapiens OX=9606 GN=RPL39 PE=1 SV=2 12 2666.5 - 1.93E+06 - - - -1.457 - 2.266 0.375 - 458.8 1 2 0 -0.0019 10 0 0 0 6.44E+07 8.72E+07 - - - 5.1093 1 221125_WJC_METTL3_EV_vs_WT_F06.15870.15870.3 1.37E-10 19/64 R.IMLFTNEDNPHGNDSAK.A "sp|P12956|XRCC6_HUMAN,tr|B1AHC9|B1AHC9_HUMAN" 2 1901.8578 1.08 84771 15870 3 1901.849595 634.9599 X-ray repair cross-complementing protein 6 OS=Homo sapiens OX=9606 GN=XRCC6 PE=1 SV=2 4.54 2666.7 - 1.31E+06 - - - -4.3016 - 3.172 0.711 - 359.6 1 2 0 -0.0082 17 0 0 0 2.33E+08 2.15E+08 - - - 9.3809 1 221125_WJC_METTL3_EV_vs_WT_F06.15871.15871.2 5.30E-10 19/38 K.IGSPSPSPSSLSDSSSSFGK.G "sp|Q8IXZ3|SP8_HUMAN,tr|A0A087X0Q6|A0A087X0Q6_HUMAN" 2 1909.8905 1.12 84772 15871 2 1909.880921 955.9525 Transcription factor Sp8 OS=Homo sapiens OX=9606 GN=SP8 PE=1 SV=3 5.84 2666.8 - 1.27E+06 - - - -5.0238 - 3.348 0.68 - 927.2 1 2 0 -0.0096 20 0 0 0 1.84E+07 1.64E+07 - - - 7.0313 0.9999 221125_WJC_METTL3_EV_vs_WT_F06.15872.15872.3 0.0125 14/36 K.QNRPIPQWIR.M "sp|P62891|RL39_HUMAN,sp|Q59GN2|R39L5_HUMAN" 2 1306.7258 0.74 84773 15872 3 1306.726636 436.5826 60S ribosomal protein L39 OS=Homo sapiens OX=9606 GN=RPL39 PE=1 SV=2 12 2666.9 - 699605 - - - 0.6107 - 2.286 0.391 - 430 1 2 0 0.0008 10 0 0 0 6.44E+07 8.66E+07 - - - 5.3137 0.9999 221125_WJC_METTL3_EV_vs_WT_F06.15873.15873.4 7.46E-05 15/78 K.K[136.11]NAALDVEPIHAFR[166.11].A "sp|Q9NRL3|STRN4_HUMAN,tr|F5GYK2|F5GYK2_HUMAN,tr|M0QZM0|M0QZM0_HUMAN" 3 1597.8695 2.87 84774 15873 4 1597.866957 400.4747 Striatin-4 OS=Homo sapiens OX=9606 GN=STRN4 PE=1 SV=2 6.75 2667.1 - 526104 - - - -1.6203 - 2.614 0.439 - 323.8 1 2 0 -0.0026 14 0 0 0 5.64E+06 1.96E+06 - - - 3.396 1 221125_WJC_METTL3_EV_vs_WT_F06.15874.15874.2 1.98E-07 14/30 R.RVTFEADENENITVVK.G "sp|Q9NX63|MIC19_HUMAN,tr|F8WAR4|F8WAR4_HUMAN,tr|C9JRZ6|C9JRZ6_HUMAN" 3 1862.9374 2.12 84775 15874 2 1862.936951 932.476 MICOS complex subunit MIC19 OS=Homo sapiens OX=9606 GN=CHCHD3 PE=1 SV=1 4.41 2667.2 - 483060 - - - -0.2448 - 3.127 0.589 - 446.7 1 2 0 -0.0005 16 0 0 0 6.24E+06 2.95E+06 - - - 6.1941 1 221125_WJC_METTL3_EV_vs_WT_F06.15880.15880.3 2.83E-09 16/64 R.IMLFTNEDNPHGNDSAK[136.11].A "sp|P12956|XRCC6_HUMAN,tr|B1AHC9|B1AHC9_HUMAN" 2 1909.872 1.06 84779 15880 3 1909.86912 637.6313 X-ray repair cross-complementing protein 6 OS=Homo sapiens OX=9606 GN=XRCC6 PE=1 SV=2 4.54 2667.7 - 4.23E+06 - - - -1.4954 - 2.737 0.594 - 179.2 1 2 0 -0.0029 17 0 0 0 2.33E+08 2.19E+08 - - - 7.7054 0.999 221125_WJC_METTL3_EV_vs_WT_F06.15881.15881.4 6.31E-05 16/84 K.GFSLLATEDK[136.11]EALK[136.11]K[136.11].Q "sp|P09874|PARP1_HUMAN,tr|A0A7I2V5E9|A0A7I2V5E9_HUMAN,tr|A0A7I2V625|A0A7I2V625_HUMAN,tr|A0A7I2V3E1|A0A7I2V3E1_HUMAN" 4 1672.9462 1.12 84780 15881 4 1672.944397 419.2438 Poly [ADP-ribose] polymerase 1 OS=Homo sapiens OX=9606 GN=PARP1 PE=1 SV=4 6.18 2667.8 - 2.28E+06 - - - -1.07 - 2.96 0.352 - 123.1 1 2 1 -0.0018 15 0 0 0 7.63E+07 6.82E+07 - - - 2.6776 0.9999 221125_WJC_METTL3_EV_vs_WT_F06.15882.15882.4 3.59E-08 20/84 K.GFSLLATEDKEALKK.Q "sp|P09874|PARP1_HUMAN,tr|A0A7I2V5E9|A0A7I2V5E9_HUMAN,tr|A0A7I2V625|A0A7I2V625_HUMAN,tr|A0A7I2V3E1|A0A7I2V3E1_HUMAN" 4 1648.9036 1.12 84781 15882 4 1648.902896 413.2332 Poly [ADP-ribose] polymerase 1 OS=Homo sapiens OX=9606 GN=PARP1 PE=1 SV=4 6.18 2667.9 - 1.87E+06 - - - -0.4191 - 3.081 0.534 - 225.7 1 2 1 -0.0007 15 0 0 0 7.63E+07 6.82E+07 - - - 4.2764 0.9999 221125_WJC_METTL3_EV_vs_WT_F06.15883.15883.3 0.000336 16/52 R.NLDIERPTYTNLNR.L "sp|Q9NY65|TBA8_HUMAN,sp|Q6PEY2|TBA3E_HUMAN,sp|P0DPH7|TBA3C_HUMAN,sp|Q71U36|TBA1A_HUMAN,sp|P0DPH8|TBA3D_HUMAN,sp|Q9H853|TBA4B_HUMAN,sp|P68366|TBA4A_HUMAN,sp|P68363|TBA1B_HUMAN,sp|Q9BQE3|TBA1C_HUMAN,tr|F8VVB9|F8VVB9_HUMAN,tr|C9JDS9|C9JDS9_HUMAN,tr|A0A7P0TA31|A0A7P0TA31_HUMAN,tr|F5H5D3|F5H5D3_HUMAN,tr|C9J2C0|C9J2C0_HUMAN,tr|F8VQQ4|F8VQQ4_HUMAN,tr|A0A7P0T945|A0A7P0T945_HUMAN" 16 1717.8747 0.63 84782 15883 3 1717.870584 573.6322 Tubulin alpha-8 chain OS=Homo sapiens OX=9606 GN=TUBA8 PE=1 SV=1 6.07 2667.9 - 1.75E+06 - - - -2.4233 - 2.906 0.405 - 282.7 1 2 0 -0.0042 14 0 0 0 3.23E+08 5.12E+08 - - - 5.8892 1 221125_WJC_METTL3_EV_vs_WT_F06.15884.15884.3 2.43E-05 18/60 R.SVYFKPSLTPSGEFRK.T sp|P49790|NU153_HUMAN 1 1841.9676 1.4 84783 15884 3 1841.965463 614.9965 Nuclear pore complex protein Nup153 OS=Homo sapiens OX=9606 GN=NUP153 PE=1 SV=2 9.7 2668 - 1.60E+06 - - - -1.152 - 3.053 0.522 - 341.5 1 2 0 -0.0021 16 0 0 0 2.97E+07 2.12E+07 - - - 7.223 0.9994 221125_WJC_METTL3_EV_vs_WT_F06.15885.15885.3 0.0044 15/52 R.IQELQQEVHQLQEK.L sp|Q66GS9|CP135_HUMAN 1 1748.9057 0.71 84784 15885 3 1748.910222 583.9758 Centrosomal protein of 135 kDa OS=Homo sapiens OX=9606 GN=CEP135 PE=1 SV=2 4.75 2668.2 - 1.01E+06 - - - 2.5782 - 2.836 0.285 - 357.3 1 2 0 0.0045 14 0 0 0 1.95E+07 2.74E+07 - - - 4.4864 0.9946 221125_WJC_METTL3_EV_vs_WT_F06.15890.15890.3 0.00693 Nov-52 K.NSFQPISSLRDDER.R sp|P98175|RBM10_HUMAN 1 1662.7962 0.3 84787 15890 3 1662.790302 555.2727 RNA-binding protein 10 OS=Homo sapiens OX=9606 GN=RBM10 PE=1 SV=3 4.56 2668.8 - 4.69E+06 - - - -3.5242 - 1.979 0.372 - 148.6 1 2 1 -0.0059 14 0 0 0 6.30E+07 2.11E+08 - - - 4.4998 0.9997 221125_WJC_METTL3_EV_vs_WT_F06.15896.15896.4 0.00143 13/78 K.KNAALDVEPIHAFR.A "sp|Q9NRL3|STRN4_HUMAN,tr|F5GYK2|F5GYK2_HUMAN,tr|M0QZM0|M0QZM0_HUMAN" 3 1579.8471 2.87 84793 15896 4 1579.844098 395.969 Striatin-4 OS=Homo sapiens OX=9606 GN=STRN4 PE=1 SV=2 6.75 2669.6 - 625888 - - - -1.885 - 2.693 0.361 - 186.3 1 2 0 -0.003 14 0 0 0 5.64E+06 1.96E+06 - - - 2.7279 1 221125_WJC_METTL3_EV_vs_WT_F06.15899.15899.3 2.09E-09 15/60 K.YTVQDESHSEWVSC[160.03]VR.F "sp|P63244|RACK1_HUMAN,tr|H0YAM7|H0YAM7_HUMAN,tr|D6RFX4|D6RFX4_HUMAN,tr|D6RFZ9|D6RFZ9_HUMAN,tr|H0YAF8|H0YAF8_HUMAN,tr|D6R9Z1|D6R9Z1_HUMAN,tr|J3KPE3|J3KPE3_HUMAN,tr|D6R9L0|D6R9L0_HUMAN,tr|D6RHH4|D6RHH4_HUMAN,tr|D6RBD0|D6RBD0_HUMAN,tr|H0Y8W2|H0Y8W2_HUMAN" 11 1980.8636 0.87 84794 15899 3 1980.86111 661.2951 Receptor of activated protein C kinase 1 OS=Homo sapiens OX=9606 GN=RACK1 PE=1 SV=3 4.65 2670 - 8.61E+06 - - - -1.252 - 3.084 0.635 - 332.4 1 2 0 -0.0025 16 0 0 0 1.25E+08 1.44E+08 - - - 8.5087 1 221125_WJC_METTL3_EV_vs_WT_F06.15900.15900.2 1.97E-07 13/26 K.SDQLLSSNENFTNK[136.11].V "sp|Q15643|TRIPB_HUMAN,tr|H0YJ97|H0YJ97_HUMAN" 2 1603.7569 1.45 84795 15900 2 1603.754961 802.8857 Thyroid receptor-interacting protein 11 OS=Homo sapiens OX=9606 GN=TRIP11 PE=1 SV=3 4.37 2670 - 4.57E+06 - - - -1.2277 - 2.762 0.605 - 533.5 1 2 0 -0.002 14 0 0 0 2.07E+08 1.43E+08 - - - 6.0584 0.9998 221125_WJC_METTL3_EV_vs_WT_F06.15901.15901.3 0.012 17/56 K.GFSLLATEDK[136.11]EALK[136.11]K[136.11].Q "sp|P09874|PARP1_HUMAN,tr|A0A7I2V5E9|A0A7I2V5E9_HUMAN,tr|A0A7I2V625|A0A7I2V625_HUMAN,tr|A0A7I2V3E1|A0A7I2V3E1_HUMAN" 4 1672.9462 0.92 84796 15901 3 1672.94585 558.656 Poly [ADP-ribose] polymerase 1 OS=Homo sapiens OX=9606 GN=PARP1 PE=1 SV=4 6.18 2670.1 - 4.52E+06 - - - -0.2014 - 3.248 0.398 - 266.2 1 2 1 -0.0003 15 0 0 0 6.37E+07 6.94E+07 - - - 6.0512 0.9999 221125_WJC_METTL3_EV_vs_WT_F06.15910.15910.4 0.000135 16/78 K.ANGVTDLLVVHEHR[166.11].G "sp|Q96G21|IMP4_HUMAN,tr|E7ENR5|E7ENR5_HUMAN,tr|B8ZZ47|B8ZZ47_HUMAN,tr|H0Y714|H0Y714_HUMAN,tr|B9A008|B9A008_HUMAN" 5 1568.8299 1.19 84803 15910 4 1568.826153 393.2147 U3 small nucleolar ribonucleoprotein protein IMP4 OS=Homo sapiens OX=9606 GN=IMP4 PE=1 SV=1 6 2671.1 - 1.42E+06 - - - -2.3623 - 3.071 0.435 - 330.2 1 2 0 -0.0037 14 0 0 0 1.81E+07 1.52E+07 - - - 3.4196 0.999 221125_WJC_METTL3_EV_vs_WT_F06.15920.15920.3 8.01E-05 15/48 K.STFSFSMTK[136.11]PSEK[136.11].E sp|P49790|NU153_HUMAN 1 1491.725 1.84 84811 15920 3 1491.719938 498.249 Nuclear pore complex protein Nup153 OS=Homo sapiens OX=9606 GN=NUP153 PE=1 SV=2 8.31 2672.2 - 1.19E+06 - - - -3.4142 - 2.369 0.332 - 173.1 1 2 0 -0.0051 13 0 0 0 1.67E+08 9.04E+07 - - - 4.5785 1 221125_WJC_METTL3_EV_vs_WT_F06.15921.15921.2 4.36E-06 15/26 K.DASSTYSQVENLNR.E "sp|Q9UFC0|LRWD1_HUMAN,tr|H7C5S6|H7C5S6_HUMAN" 2 1582.7223 0.47 84812 15921 2 1582.722218 792.3684 Leucine-rich repeat and WD repeat-containing protein 1 OS=Homo sapiens OX=9606 GN=LRWD1 PE=1 SV=2 4.37 2672.4 - 1.19E+06 - - - -0.0701 - 3.16 0.6 - 867 1 2 0 -0.0001 14 0 0 0 1.97E+07 4.14E+07 - - - 6.3599 0.9998 221125_WJC_METTL3_EV_vs_WT_F06.15922.15922.2 3.76E-05 16/26 R.NLDIER[166.11]PTYTNLNR[166.11].L "sp|Q9NY65|TBA8_HUMAN,sp|Q6PEY2|TBA3E_HUMAN,sp|P0DPH7|TBA3C_HUMAN,sp|Q71U36|TBA1A_HUMAN,sp|P0DPH8|TBA3D_HUMAN,sp|Q9H853|TBA4B_HUMAN,sp|P68366|TBA4A_HUMAN,sp|P68363|TBA1B_HUMAN,sp|Q9BQE3|TBA1C_HUMAN,tr|F8VVB9|F8VVB9_HUMAN,tr|C9JDS9|C9JDS9_HUMAN,tr|A0A7P0TA31|A0A7P0TA31_HUMAN,tr|F5H5D3|F5H5D3_HUMAN,tr|C9J2C0|C9J2C0_HUMAN,tr|F8VQQ4|F8VQQ4_HUMAN,tr|A0A7P0T945|A0A7P0T945_HUMAN" 16 1737.8913 0.5 84813 15922 2 1737.89264 869.9529 Tubulin alpha-8 chain OS=Homo sapiens OX=9606 GN=TUBA8 PE=1 SV=1 6.07 2672.5 - 1.15E+06 - - - 0.7785 - 2.301 0.471 - 258 1 2 0 0.0014 14 0 0 0 1.45E+07 2.89E+07 - - - 4.6106 1 221125_WJC_METTL3_EV_vs_WT_F06.15926.15926.4 999 Jan-66 G.C[160.03]NC[160.03]C[160.03]C[160.03]RC[160.03]C[160.03]FC[160.03]C[160.03]R.R sp|Q9NSI5|IGSF5_HUMAN 1 1871.5693 40.74 84815 15926 4 1871.557022 468.8996 Immunoglobulin superfamily member 5 OS=Homo sapiens OX=9606 GN=IGSF5 PE=2 SV=2 8.23 2673 - 5.04E+06 - - - -6.5688 - 0.161 0.869 - 1.1 1 1 1 -0.0123 12 0 0 0 7.82E+07 1.92E+06 - - - 6.0952 0.9997 221125_WJC_METTL3_EV_vs_WT_F06.15927.15927.3 7.26E-08 18/60 K.IGR[166.11]IEDVTPIPSDSTR[166.11].R "sp|P62263|RS14_HUMAN,tr|A0A2R8Y811|A0A2R8Y811_HUMAN" 2 1774.9328 2.58 84816 15927 3 1774.926732 592.6515 40S ribosomal protein S14 OS=Homo sapiens OX=9606 GN=RPS14 PE=1 SV=3 4.56 2673.1 - 1.27E+06 - - - -3.4283 - 3.3 0.541 - 357.1 1 2 1 -0.0061 16 0 0 0 5.08E+07 1.97E+07 - - - 7.6334 0.9997 221125_WJC_METTL3_EV_vs_WT_F06.15929.15929.4 0.0197 13/90 K.YSHLQPGDHLTDITLK[136.11].V "sp|Q15046|SYK_HUMAN,tr|H3BVA8|H3BVA8_HUMAN" 2 1844.9512 1.42 84818 15929 4 1844.946982 462.2451 Lysine--tRNA ligase OS=Homo sapiens OX=9606 GN=KARS1 PE=1 SV=3 5.98 2673.2 - 3.29E+06 - - - -2.2933 - 2.145 0.394 - 70.3 1 2 0 -0.0042 16 0 0 0 1.17E+08 8.23E+07 - - - 2.923 0.9999 221125_WJC_METTL3_EV_vs_WT_F06.15930.15930.3 7.61E-07 18/60 K.IGRIEDVTPIPSDSTR.R "sp|P62263|RS14_HUMAN,tr|A0A2R8Y811|A0A2R8Y811_HUMAN" 2 1754.9163 2.61 84819 15930 3 1754.915299 585.9794 40S ribosomal protein S14 OS=Homo sapiens OX=9606 GN=RPS14 PE=1 SV=3 4.56 2673.4 - 2.11E+06 - - - -0.5573 - 2.898 0.493 - 423.7 1 2 1 -0.001 16 0 0 0 5.13E+07 1.97E+07 - - - 6.7663 0.9999 221125_WJC_METTL3_EV_vs_WT_F06.15931.15931.4 1.79E-06 18/78 K.ANGVTDLLVVHEHR.G "sp|Q96G21|IMP4_HUMAN,tr|E7ENR5|E7ENR5_HUMAN,tr|B8ZZ47|B8ZZ47_HUMAN,tr|H0Y714|H0Y714_HUMAN,tr|B9A008|B9A008_HUMAN" 5 1558.8216 1.19 84820 15931 4 1558.818649 390.7127 U3 small nucleolar ribonucleoprotein protein IMP4 OS=Homo sapiens OX=9606 GN=IMP4 PE=1 SV=1 6 2673.5 - 1.65E+06 - - - -1.886 - 3.36 0.433 - 411.8 1 2 0 -0.0029 14 0 0 0 1.81E+07 1.52E+07 - - - 3.4351 1 221125_WJC_METTL3_EV_vs_WT_F06.15935.15935.4 1.75E-06 17/78 R.IVLNPNKPVVEWHR.E sp|Q9BRR6|ADPGK_HUMAN 1 1699.9522 0.99 84824 15935 4 1699.950932 425.9953 ADP-dependent glucokinase OS=Homo sapiens OX=9606 GN=ADPGK PE=1 SV=1 8.75 2674 - 948588 - - - -0.7512 - 3.045 0.484 - 229.6 1 2 0 -0.0013 14 0 0 0 7.33E+07 7.39E+07 - - - 3.8436 1 221125_WJC_METTL3_EV_vs_WT_F06.15936.15936.3 5.55E-08 18/56 R.TEMEDLMSSK[136.11]DDVGK[136.11].S sp|P35579|MYH9_HUMAN 1 1699.7616 1.46 84825 15936 3 1699.764765 567.5945 Myosin-9 OS=Homo sapiens OX=9606 GN=MYH9 PE=1 SV=4 4.1 2674.1 - 904714 - - - 1.8897 - 3.249 0.65 - 362 1 2 1 0.0032 15 0 0 0 1.33E+08 9.13E+07 - - - 8.8607 0.9001 221125_WJC_METTL3_EV_vs_WT_F06.15937.15937.2 0.638 24-May K.KFMDQHPEMDFSK.A sp|Q9Y266|NUDC_HUMAN 1 1638.717 999 84826 15937 2 1638.713061 820.3658 Nuclear migration protein nudC OS=Homo sapiens OX=9606 GN=NUDC PE=1 SV=1 5.38 2674.2 - 746886 - - - -2.4336 - 0.944 0.119 - 68.3 1 2 0 -0.004 13 0 0 0 1.05E+07 0.00E+00 - - - -0.2292 1 221125_WJC_METTL3_EV_vs_WT_F06.15938.15938.2 9.98E-09 15/30 K.NQVALNPQNTVFDAK[136.11]R[166.11].L "sp|P0DMV8|HS71A_HUMAN,sp|P0DMV9|HS71B_HUMAN,tr|A0A0G2JIW1|A0A0G2JIW1_HUMAN" 3 1831.966 0.39 84827 15938 2 1831.964536 916.9903 Heat shock 70 kDa protein 1A OS=Homo sapiens OX=9606 GN=HSPA1A PE=1 SV=1 8.75 2674.4 - 533917 - - - -0.78 - 3.274 0.597 - 691.9 1 2 0 -0.0014 16 0 0 0 7.88E+06 2.02E+07 - - - 6.3659 0.9998 221125_WJC_METTL3_EV_vs_WT_F06.15943.15943.3 2.82E-07 21/48 K.DRLLASTLVHSVK.K "sp|Q9NYF8|BCLF1_HUMAN,tr|E9PKI6|E9PKI6_HUMAN,tr|A0A1W2PQ43|A0A1W2PQ43_HUMAN,tr|E9PK91|E9PK91_HUMAN,tr|E9PJA7|E9PJA7_HUMAN,tr|E9PK09|E9PK09_HUMAN,tr|E9PQN2|E9PQN2_HUMAN" 7 1437.8304 2.12 84830 15943 3 1437.827728 480.2841 Bcl-2-associated transcription factor 1 OS=Homo sapiens OX=9606 GN=BCLAF1 PE=1 SV=2 8.75 2674.9 - 3.01E+06 - - - -1.8326 - 3.304 0.429 - 730 1 2 1 -0.0026 13 0 0 0 2.46E+08 1.16E+08 - - - 6.5626 1 221125_WJC_METTL3_EV_vs_WT_F06.15944.15944.3 1.01E-11 18/60 K.YSHLQPGDHLTDITLK[136.11].V "sp|Q15046|SYK_HUMAN,tr|H3BVA8|H3BVA8_HUMAN" 2 1844.9512 0.48 84831 15944 3 1844.948271 615.991 Lysine--tRNA ligase OS=Homo sapiens OX=9606 GN=KARS1 PE=1 SV=3 5.98 2674.9 - 3.52E+06 - - - -1.5946 - 3.752 0.548 - 430 1 2 0 -0.0029 16 0 0 0 3.75E+07 7.85E+07 - - - 8.0417 0.9999 221125_WJC_METTL3_EV_vs_WT_F06.15946.15946.3 9.47E-05 18/48 K.DR[166.11]LLASTLVHSVK[136.11].K "sp|Q9NYF8|BCLF1_HUMAN,tr|E9PKI6|E9PKI6_HUMAN,tr|A0A1W2PQ43|A0A1W2PQ43_HUMAN,tr|E9PK91|E9PK91_HUMAN,tr|E9PJA7|E9PJA7_HUMAN,tr|E9PK09|E9PK09_HUMAN,tr|E9PQN2|E9PQN2_HUMAN" 7 1455.8528 2.12 84833 15946 3 1455.850726 486.2916 Bcl-2-associated transcription factor 1 OS=Homo sapiens OX=9606 GN=BCLAF1 PE=1 SV=2 8.75 2675.1 - 2.76E+06 - - - -1.4473 - 3.719 0.545 - 578.4 1 2 1 -0.0021 13 0 0 0 2.46E+08 1.16E+08 - - - 8.1768 1 221125_WJC_METTL3_EV_vs_WT_F06.15947.15947.3 6.22E-06 13/48 K.STFSFSMTKPSEK.E sp|P49790|NU153_HUMAN 1 1475.6966 1.82 84834 15947 3 1475.69512 492.9062 Nuclear pore complex protein Nup153 OS=Homo sapiens OX=9606 GN=NUP153 PE=1 SV=2 8.31 2675.2 - 2.48E+06 - - - -1.0239 - 2.518 0.556 - 108.9 1 2 0 -0.0015 13 0 0 0 1.67E+08 9.16E+07 - - - 7.2422 1 221125_WJC_METTL3_EV_vs_WT_F06.15948.15948.4 1.50E-07 21/78 R.IVLNPNK[136.11]PVVEWHR[166.11].E sp|Q9BRR6|ADPGK_HUMAN 1 1717.9747 0.99 84835 15948 4 1717.971359 430.5009 ADP-dependent glucokinase OS=Homo sapiens OX=9606 GN=ADPGK PE=1 SV=1 8.75 2675.3 - 1.72E+06 - - - -1.9325 - 3.389 0.563 - 424.3 1 2 0 -0.0033 14 0 0 0 7.33E+07 7.39E+07 - - - 4.5696 0.9997 221125_WJC_METTL3_EV_vs_WT_F06.15950.15950.4 0.000246 14/108 K.TITGFQTHTTPVLLAHGER[166.11].A sp|Q13200|PSMD2_HUMAN 1 2088.0992 0.6 84837 15950 4 2088.101883 523.0321 26S proteasome non-ATPase regulatory subunit 2 OS=Homo sapiens OX=9606 GN=PSMD2 PE=1 SV=3 6.61 2675.4 - 1.58E+06 - - - 1.305 - 2.183 0.368 - 55.5 1 2 0 0.0027 19 0 0 0 6.81E+07 1.13E+08 - - - 2.6924 0.9997 221125_WJC_METTL3_EV_vs_WT_F06.15951.15951.2 0.000134 26-Oct R.NLDIERPTYTNLNR.L "sp|Q9NY65|TBA8_HUMAN,sp|Q6PEY2|TBA3E_HUMAN,sp|P0DPH7|TBA3C_HUMAN,sp|Q71U36|TBA1A_HUMAN,sp|P0DPH8|TBA3D_HUMAN,sp|Q9H853|TBA4B_HUMAN,sp|P68366|TBA4A_HUMAN,sp|P68363|TBA1B_HUMAN,sp|Q9BQE3|TBA1C_HUMAN,tr|F8VVB9|F8VVB9_HUMAN,tr|C9JDS9|C9JDS9_HUMAN,tr|A0A7P0TA31|A0A7P0TA31_HUMAN,tr|F5H5D3|F5H5D3_HUMAN,tr|C9J2C0|C9J2C0_HUMAN,tr|F8VQQ4|F8VQQ4_HUMAN,tr|A0A7P0T945|A0A7P0T945_HUMAN" 16 1717.8747 0.5 84838 15951 2 1717.874113 859.9446 Tubulin alpha-8 chain OS=Homo sapiens OX=9606 GN=TUBA8 PE=1 SV=1 6.07 2675.6 - 1.07E+06 - - - -0.3691 - 2.063 0.375 - 86.5 1 2 0 -0.0006 14 0 0 0 1.45E+07 2.89E+07 - - - 3.6278 1 221125_WJC_METTL3_EV_vs_WT_F06.15952.15952.4 1.85E-06 17/72 R.EDAMAMVDHC[160.03]LKK.A "sp|P43243|MATR3_HUMAN,tr|B3KM87|B3KM87_HUMAN,tr|A8MXP9|A8MXP9_HUMAN,tr|A0A0R4J2E8|A0A0R4J2E8_HUMAN,tr|H0Y8T4|H0Y8T4_HUMAN,tr|D6REM6|D6REM6_HUMAN" 6 1546.6942 1.25 84839 15952 4 1546.691589 387.6808 Matrin-3 OS=Homo sapiens OX=9606 GN=MATR3 PE=1 SV=2 5.38 2675.7 - 985243 - - - -1.6913 - 2.855 0.517 - 298.9 1 2 0 -0.0026 13 0 0 0 5.07E+07 4.05E+07 - - - 4.1142 0.9174 221125_WJC_METTL3_EV_vs_WT_F06.15953.15953.3 4.57 14/52 K.GC[160.03]TIVKPFNLSQGK.K sp|Q9ULW0|TPX2_HUMAN 1 1547.813 4.78 84840 15953 3 1547.815003 516.9449 Targeting protein for Xklp2 OS=Homo sapiens OX=9606 GN=TPX2 PE=1 SV=2 9.31 2675.8 - 901622 - - - 1.2947 - 1.708 0.066 - 160.3 1 2 0 0.002 14 0 0 0 2.22E+08 4.65E+07 - - - 0.6979 0.9998 221125_WJC_METTL3_EV_vs_WT_F06.15957.15957.4 0.00155 15/96 K.SIVIRPLEPQPAPHLAR.E "sp|Q15029|U5S1_HUMAN,tr|K7EP67|K7EP67_HUMAN" 2 1893.0949 0.78 84842 15957 4 1893.094088 474.281 116 kDa U5 small nuclear ribonucleoprotein component OS=Homo sapiens OX=9606 GN=EFTUD2 PE=1 SV=1 9.34 2676.3 - 2.40E+06 - - - -0.403 - 2.222 0.384 - 110.1 1 2 0 -0.0008 17 0 0 0 1.48E+08 1.89E+08 - - - 2.8453 1 221125_WJC_METTL3_EV_vs_WT_F06.15959.15959.3 5.94E-06 14/48 R.EDAMAMVDHC[160.03]LKK.A "sp|P43243|MATR3_HUMAN,tr|B3KM87|B3KM87_HUMAN,tr|A8MXP9|A8MXP9_HUMAN,tr|A0A0R4J2E8|A0A0R4J2E8_HUMAN,tr|H0Y8T4|H0Y8T4_HUMAN,tr|D6REM6|D6REM6_HUMAN" 6 1546.6942 1.18 84844 15959 3 1546.693012 516.572 Matrin-3 OS=Homo sapiens OX=9606 GN=MATR3 PE=1 SV=2 5.38 2676.5 - 2.15E+06 - - - -0.7713 - 2.613 0.575 - 185.3 1 2 0 -0.0012 13 0 0 0 5.72E+07 4.86E+07 - - - 7.5545 1 221125_WJC_METTL3_EV_vs_WT_F06.15960.15960.3 1.10E-07 19/64 R.QQEESFQEQSALAAEAR.E "sp|Q9BSV6|SEN34_HUMAN,tr|A0A590UJ73|A0A590UJ73_HUMAN,tr|E7EQB3|E7EQB3_HUMAN,tr|A0A0G2JNK5|A0A0G2JNK5_HUMAN,tr|A0A0G2JNL0|A0A0G2JNL0_HUMAN,tr|A0A590UJW4|A0A590UJW4_HUMAN,tr|B0V3J0|B0V3J0_HUMAN" 7 1920.8813 5.25 84845 15960 3 1920.879239 641.3011 tRNA-splicing endonuclease subunit Sen34 OS=Homo sapiens OX=9606 GN=TSEN34 PE=1 SV=1 4.09 2676.6 - 1.32E+06 - - - -1.0979 - 3.047 0.588 - 349.5 1 2 0 -0.0021 17 0 0 0 2.07E+07 3.95E+06 - - - 7.9097 1 221125_WJC_METTL3_EV_vs_WT_F06.15963.15963.2 1.11E-10 17/32 R.QQEESFQEQSALAAEAR.E "sp|Q9BSV6|SEN34_HUMAN,tr|A0A590UJ73|A0A590UJ73_HUMAN,tr|E7EQB3|E7EQB3_HUMAN,tr|A0A0G2JNK5|A0A0G2JNK5_HUMAN,tr|A0A0G2JNL0|A0A0G2JNL0_HUMAN,tr|A0A590UJW4|A0A590UJW4_HUMAN,tr|B0V3J0|B0V3J0_HUMAN" 7 1920.8813 3.8 84848 15963 2 1920.878493 961.448 tRNA-splicing endonuclease subunit Sen34 OS=Homo sapiens OX=9606 GN=TSEN34 PE=1 SV=1 4.09 2677 - 597840 - - - -1.4863 - 3.458 0.7 - 1271.8 1 2 0 -0.0029 17 0 0 0 8.43E+06 2.22E+06 - - - 7.2606 1 221125_WJC_METTL3_EV_vs_WT_F06.15967.15967.4 4.10E-08 15/72 R.EDAMAMVDHC[160.03]LK[136.11]K[136.11].A "sp|P43243|MATR3_HUMAN,tr|B3KM87|B3KM87_HUMAN,tr|A8MXP9|A8MXP9_HUMAN,tr|A0A0R4J2E8|A0A0R4J2E8_HUMAN,tr|H0Y8T4|H0Y8T4_HUMAN,tr|D6REM6|D6REM6_HUMAN" 6 1562.7226 1.25 84850 15967 4 1562.718684 391.6879 Matrin-3 OS=Homo sapiens OX=9606 GN=MATR3 PE=1 SV=2 5.38 2677.5 - 2.20E+06 - - - -2.5091 - 2.972 0.571 - 221.9 1 2 0 -0.0039 13 0 0 0 5.07E+07 4.05E+07 - - - 4.5988 0.9987 221125_WJC_METTL3_EV_vs_WT_F06.15971.15971.3 0.000202 Nov-36 R.IKFEMEQNLR.Q "sp|P35527|K1C9_HUMAN,tr|K7EQQ3|K7EQQ3_HUMAN" 2 1306.6704 255.14 84854 15971 3 1306.668482 436.5641 "Keratin, type I cytoskeletal 9 OS=Homo sapiens OX=9606 GN=KRT9 PE=1 SV=3" 6.14 2677.8 - 1.63E+06 - - - -1.4349 - 2.268 0.317 - 201.8 1 2 1 -0.0019 10 0 0 0 2.48E+08 9.73E+05 - - - 4.4653 0.9985 221125_WJC_METTL3_EV_vs_WT_F06.15973.15973.3 1.20E-05 18/52 Y.RLNPQEYLTSTAC[160.03]R.R "sp|Q8TAQ2|SMRC2_HUMAN,sp|Q92922|SMRC1_HUMAN,tr|F8VXC8|F8VXC8_HUMAN" 3 1707.8363 0.16 84856 15973 3 1707.835328 570.286 SWI\SNF complex subunit SMARCC2 OS=Homo sapiens OX=9606 GN=SMARCC2 PE=1 SV=1 8.22 2678 - 1.09E+06 - - - -0.5416 - 3.222 0.536 - 477.4 1 1 0 -0.0009 14 0 0 0 2.49E+07 1.57E+08 - - - 7.6249 0.9997 221125_WJC_METTL3_EV_vs_WT_F06.15974.15974.2 4.62E-07 24-Dec K.STFSFSMTKPSEK.E sp|P49790|NU153_HUMAN 1 1475.6966 1.2 84857 15974 2 1475.692965 738.8556 Nuclear pore complex protein Nup153 OS=Homo sapiens OX=9606 GN=NUP153 PE=1 SV=2 8.31 2678.1 - 773540 - - - -2.4843 - 2.48 0.537 - 348.8 1 2 0 -0.0037 13 0 0 0 9.08E+06 7.55E+06 - - - 5.3372 0.9999 221125_WJC_METTL3_EV_vs_WT_F06.15976.15976.3 4.57E-07 18/64 K.SIVIRPLEPQPAPHLAR.E "sp|Q15029|U5S1_HUMAN,tr|K7EP67|K7EP67_HUMAN" 2 1893.0949 2.63 84859 15976 3 1893.09299 632.0389 116 kDa U5 small nuclear ribonucleoprotein component OS=Homo sapiens OX=9606 GN=EFTUD2 PE=1 SV=1 9.34 2678.4 - 722818 - - - -0.983 - 2.457 0.408 - 349.7 1 2 0 -0.0019 17 0 0 0 1.64E+07 6.24E+06 - - - 5.3593 0.9998 221125_WJC_METTL3_EV_vs_WT_F06.15979.15979.2 2.38E-06 14/26 K.SDQLLSSNENFTNK.V "sp|Q15643|TRIPB_HUMAN,tr|H0YJ97|H0YJ97_HUMAN" 2 1595.7427 1.45 84861 15979 2 1595.740021 798.8786 Thyroid receptor-interacting protein 11 OS=Homo sapiens OX=9606 GN=TRIP11 PE=1 SV=3 4.37 2678.7 - 2.31E+06 - - - -1.6976 - 2.483 0.472 - 325.2 1 2 0 -0.0027 14 0 0 0 2.07E+08 1.43E+08 - - - 4.8086 1 221125_WJC_METTL3_EV_vs_WT_F06.15982.15982.2 5.61E-08 16/32 S.TASAVPELATDPELEK[136.11]K[136.11].L "sp|Q86U44|MTA70_HUMAN,tr|B4E349|B4E349_HUMAN,tr|F5H6D8|F5H6D8_HUMAN,tr|H0YFV6|H0YFV6_HUMAN,tr|B4DTN4|B4DTN4_HUMAN" 5 1813.9644 0.001 84863 15982 2 1813.960168 907.9895 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 4.41 2679 - 1.40E+06 - - - -2.3385 - 2.733 0.596 - 667.7 1 1 0 -0.0042 17 0 0 0 0.00E+00 4.06E+07 - - - 5.9135 1 221125_WJC_METTL3_EV_vs_WT_F06.15983.15983.3 3.55E-06 16/60 K.EEYQQTWYHEGPNSLK[136.11].V sp|O43172|PRP4_HUMAN 1 2015.9105 2.43 84864 15983 3 2015.911205 672.9774 U4\U6 small nuclear ribonucleoprotein Prp4 OS=Homo sapiens OX=9606 GN=PRPF4 PE=1 SV=2 4.75 2679.2 - 1.36E+06 - - - 0.3646 - 2.956 0.492 - 393.1 1 2 0 0.0007 16 0 0 0 8.09E+07 3.33E+07 - - - 6.8061 0.9839 221125_WJC_METTL3_EV_vs_WT_F06.15984.15984.3 0.0107 Dec-60 K.GISQTNLITTVTPEK[136.11]K[136.11].A "sp|Q9Y2J2|E41L3_HUMAN,tr|A0A1B0GTF8|A0A1B0GTF8_HUMAN,tr|A0A0A0MRA8|A0A0A0MRA8_HUMAN,tr|A0A0J9YW26|A0A0J9YW26_HUMAN,tr|A8K968|A8K968_HUMAN,tr|A0A0A0MSA4|A0A0A0MSA4_HUMAN" 6 1744.9906 1.45 84865 15984 3 1744.991414 582.6708 Band 4.1-like protein 3 OS=Homo sapiens OX=9606 GN=EPB41L3 PE=1 SV=2 8.59 2679.3 - 940957 - - - 0.4865 - 2.079 0.099 - 105.5 1 2 0 0.0008 16 0 0 0 4.23E+07 2.91E+07 - - - 1.5214 1 221125_WJC_METTL3_EV_vs_WT_F06.15990.15990.4 0.000968 18/108 K.TITGFQTHTTPVLLAHGER.A sp|Q13200|PSMD2_HUMAN 1 2078.0909 0.6 84869 15990 4 2078.09392 520.53 26S proteasome non-ATPase regulatory subunit 2 OS=Homo sapiens OX=9606 GN=PSMD2 PE=1 SV=3 6.61 2679.8 - 3.76E+06 - - - 1.459 - 3.05 0.5 - 137.9 1 2 0 0.003 19 0 0 0 6.79E+07 1.13E+08 - - - 3.9544 0.9977 221125_WJC_METTL3_EV_vs_WT_F06.15991.15991.3 6.14E-07 16/52 L.KLTFDSSFSPNTGK.K "sp|P21796|VDAC1_HUMAN,tr|C9JI87|C9JI87_HUMAN" 2 1527.7569 1.34 84870 15991 3 1527.755448 510.2596 Voltage-dependent anion-selective channel protein 1 OS=Homo sapiens OX=9606 GN=VDAC1 PE=1 SV=2 8.59 2679.9 - 2.68E+06 - - - -0.9655 - 2.486 0.536 - 234.5 1 1 0 -0.0015 14 0 0 0 9.10E+07 6.80E+07 - - - 6.9356 0.9968 221125_WJC_METTL3_EV_vs_WT_F06.15992.15992.2 0.0561 18-Oct R.IKFEMEQNLR.Q "sp|P35527|K1C9_HUMAN,tr|K7EQQ3|K7EQQ3_HUMAN" 2 1306.6704 18.26 84871 15992 2 1306.671462 654.3425 "Keratin, type I cytoskeletal 9 OS=Homo sapiens OX=9606 GN=KRT9 PE=1 SV=3" 6.14 2680 - 1.12E+06 - - - 0.8457 - 1.886 0.414 - 272 1 2 1 0.0011 10 0 0 0 5.46E+07 2.99E+06 - - - 3.8694 1 221125_WJC_METTL3_EV_vs_WT_F06.16000.16000.3 9.33E-11 22/68 K.TGQEVVFVAEPDNKNVYK.F sp|P04844|RPN2_HUMAN 1 2036.0215 0.95 84876 16000 3 2036.00632 679.6811 Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit 2 OS=Homo sapiens OX=9606 GN=RPN2 PE=1 SV=3 4.68 2681.1 - 2.11E+06 - - - -7.4415 - 4.052 0.596 - 594.4 1 2 1 -0.0152 18 0 0 0 2.41E+07 2.53E+07 - - - 8.6648 0.9999 221125_WJC_METTL3_EV_vs_WT_F06.16007.16007.3 0.00438 16/44 K.MIKPFFHSLSEK.Y sp|P10599|THIO_HUMAN 1 1462.7643 0.62 84881 16007 3 1462.761954 488.5954 Thioredoxin OS=Homo sapiens OX=9606 GN=TXN PE=1 SV=3 8.37 2681.8 - 854793 - - - -1.5744 - 2.7 0.405 - 271.1 1 2 0 -0.0023 12 0 0 0 1.81E+07 2.93E+07 - - - 5.8079 0.9966 221125_WJC_METTL3_EV_vs_WT_F06.16008.16008.3 0.000231 17/52 L.K[136.11]LTFDSSFSPNTGK[136.11].K "sp|P21796|VDAC1_HUMAN,tr|C9JI87|C9JI87_HUMAN" 2 1543.7853 1.36 84882 16008 3 1543.784773 515.6024 Voltage-dependent anion-selective channel protein 1 OS=Homo sapiens OX=9606 GN=VDAC1 PE=1 SV=2 8.59 2681.9 - 2.25E+06 - - - -0.3563 - 2.914 0.45 - 320.6 1 1 0 -0.0006 14 0 0 0 9.24E+07 6.80E+07 - - - 6.3992 1 221125_WJC_METTL3_EV_vs_WT_F06.16018.16018.3 0.974 22/60 R.LHNQQALSSSIEEGLR.M sp|Q06587|RING1_HUMAN 1 1780.9068 1.16 84888 16018 3 1780.906743 594.6429 E3 ubiquitin-protein ligase RING1 OS=Homo sapiens OX=9606 GN=RING1 PE=1 SV=2 5.4 2683.1 - 2.41E+06 - - - -0.018 - 3.969 0.484 - 911.3 1 2 0 0 16 0 0 0 5.34E+07 4.62E+07 - - - 7.4732 1 221125_WJC_METTL3_EV_vs_WT_F06.16020.16020.2 2.60E-12 21/34 K.YVHYEIDAC[160.03]MDSEAPGSK.D "sp|Q86U44|MTA70_HUMAN,tr|H0YFV6|H0YFV6_HUMAN" 2 2070.8663 0.01 84889 16020 2 2071.854818 1036.4404 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 4.31 2683.3 - 5.39E+06 - - - 477.349 - 4.096 0.74 - 933.8 1 2 0 0.9885 18 0 0 0 1.99E+08 2.68E+10 - - - 7.6628 1 221125_WJC_METTL3_EV_vs_WT_F06.16021.16021.3 4.07E-05 24/60 R.LHNQQALSSSIEEGLR[166.11].M sp|Q06587|RING1_HUMAN 1 1790.915 1.15 84890 16021 3 1790.912678 597.979 E3 ubiquitin-protein ligase RING1 OS=Homo sapiens OX=9606 GN=RING1 PE=1 SV=2 5.4 2683.4 - 3.27E+06 - - - -1.3217 - 3.293 0.451 - 683.4 1 2 0 -0.0024 16 0 0 0 5.34E+07 4.65E+07 - - - 6.6255 1 221125_WJC_METTL3_EV_vs_WT_F06.16026.16026.3 2.62E-07 15/48 K.HPDSSVNFAEFSK[136.11].K "sp|P26583|HMGB2_HUMAN,tr|D6R9A6|D6R9A6_HUMAN" 2 1471.6823 0.11 84892 16026 3 1471.679089 491.568 High mobility group protein B2 OS=Homo sapiens OX=9606 GN=HMGB2 PE=1 SV=2 5.32 2684.1 - 2.35E+06 - - - -2.1873 - 2.892 0.619 - 323.7 1 2 0 -0.0032 13 0 0 0 1.93E+07 1.69E+08 - - - 8.3196 0.9999 221125_WJC_METTL3_EV_vs_WT_F06.16034.16034.3 0.00133 15/48 K.SDHPGISITDLSK[136.11].K "sp|Q08945|SSRP1_HUMAN,tr|A0A0U1RRK2|A0A0U1RRK2_HUMAN" 2 1376.7027 0.77 84894 16034 3 1376.699714 459.9082 FACT complex subunit SSRP1 OS=Homo sapiens OX=9606 GN=SSRP1 PE=1 SV=1 5.19 2685.2 - 2.37E+06 - - - -2.1755 - 2.561 0.421 - 348.6 1 2 0 -0.003 13 0 0 0 1.91E+08 2.48E+08 - - - 5.7826 1 221125_WJC_METTL3_EV_vs_WT_F06.16036.16036.4 2.06E-07 19/102 K.YVHYEIDAC[160.03]MDSEAPGSK[136.11].D "sp|Q86U44|MTA70_HUMAN,tr|H0YFV6|H0YFV6_HUMAN" 2 2078.8805 0.01 84895 16036 4 2079.876584 520.7274 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 4.31 2685.4 - 3.36E+07 - - - 479.1483 - 3.434 0.705 - 279.4 1 2 0 0.9961 18 0 0 0 1.03E+07 1.54E+09 - - - 5.509 1 221125_WJC_METTL3_EV_vs_WT_F06.16047.16047.2 1.23E-13 16/38 R.FSSC[160.03]GGGGGSFGAGGGFGSR.S sp|P04264|K2C1_HUMAN 1 1764.7274 999 84898 16047 2 1764.722086 883.371 "Keratin, type II cytoskeletal 1 OS=Homo sapiens OX=9606 GN=KRT1 PE=1 SV=6" 8.25 2687 - 2.34E+07 - - - -3.0288 - 3.696 0.773 - 797.5 1 2 0 -0.0053 20 0 0 0 2.58E+09 0.00E+00 - - - 7.9626 0.9988 221125_WJC_METTL3_EV_vs_WT_F06.16058.16058.2 8.74E-07 24/34 R.HIISATSLSTSPTELGSR.N sp|Q5JSZ5|PRC2B_HUMAN 1 1855.964 11.65 84903 16058 2 1855.955697 928.9893 Protein PRRC2B OS=Homo sapiens OX=9606 GN=PRRC2B PE=1 SV=2 6.75 2688.4 - 1.95E+06 - - - -4.45 - 2.52 0.542 - 454.7 1 2 0 -0.0083 18 0 0 0 6.33E+07 5.44E+06 - - - 5.314 1 221125_WJC_METTL3_EV_vs_WT_F06.16066.16066.3 2.64E-07 20/44 K.NQWQLSADDLK[136.11]K[136.11].L "sp|P09543|CN37_HUMAN,tr|K7ERC4|K7ERC4_HUMAN" 2 1460.7594 0.58 84906 16066 3 1460.757345 487.9271 "2',3'-cyclic-nucleotide 3'-phosphodiesterase OS=Homo sapiens OX=9606 GN=CNP PE=1 SV=2" 5.96 2689.4 - 3.34E+06 - - - -1.4362 - 3.212 0.547 - 666.9 1 2 0 -0.0021 12 0 0 0 5.69E+07 9.88E+07 - - - 7.8724 0.9973 221125_WJC_METTL3_EV_vs_WT_F06.16074.16074.4 4.69E-08 19/114 F.SSMAEVDAAMAAR[166.11]PHSIDGR[166.11].V "sp|P22626|ROA2_HUMAN,tr|A0A7I2YQN4|A0A7I2YQN4_HUMAN,tr|A0A7I2V4N0|A0A7I2V4N0_HUMAN,tr|A0A024RA28|A0A024RA28_HUMAN,tr|A0A7I2V4N1|A0A7I2V4N1_HUMAN,tr|A0A7I2V4I6|A0A7I2V4I6_HUMAN,tr|A0A087WUI2|A0A087WUI2_HUMAN,tr|A0A7I2V4S4|A0A7I2V4S4_HUMAN,tr|A0A7I2V323|A0A7I2V323_HUMAN,tr|A0A7I2V3P1|A0A7I2V3P1_HUMAN,tr|A0A7I2V3P7|A0A7I2V3P7_HUMAN" 11 2090.974 1.55 84908 16074 4 2090.970551 523.7508 Heterogeneous nuclear ribonucleoproteins A2\B1 OS=Homo sapiens OX=9606 GN=HNRNPA2B1 PE=1 SV=2 5.36 2690.6 - 3.02E+06 - - - -1.6719 - 3.39 0.556 - 264.6 1 1 0 -0.0035 20 0 0 0 1.37E+08 8.83E+07 - - - 4.4726 0.9999 221125_WJC_METTL3_EV_vs_WT_F06.16078.16078.3 1.29E-05 19/44 K.NQWQLSADDLKK.L "sp|P09543|CN37_HUMAN,tr|K7ERC4|K7ERC4_HUMAN" 2 1444.731 0.65 84909 16078 3 1444.727625 482.5843 "2',3'-cyclic-nucleotide 3'-phosphodiesterase OS=Homo sapiens OX=9606 GN=CNP PE=1 SV=2" 5.96 2691.1 - 1.36E+06 - - - -2.3658 - 3.379 0.449 - 745.9 1 2 0 -0.0034 12 0 0 0 5.64E+07 8.69E+07 - - - 6.9199 0.9999 221125_WJC_METTL3_EV_vs_WT_F06.16080.16080.3 0.00259 16/48 K.SDHPGISITDLSK.K "sp|Q08945|SSRP1_HUMAN,tr|A0A0U1RRK2|A0A0U1RRK2_HUMAN" 2 1368.6885 0.77 84910 16080 3 1368.686493 457.2368 FACT complex subunit SSRP1 OS=Homo sapiens OX=9606 GN=SSRP1 PE=1 SV=1 5.19 2691.3 - 3.26E+06 - - - -1.4729 - 2.724 0.439 - 459.7 1 2 0 -0.002 13 0 0 0 1.91E+08 2.48E+08 - - - 6.1508 1 221125_WJC_METTL3_EV_vs_WT_F06.16083.16083.2 2.74E-07 15/22 K.NVQDAIADAEQR.G sp|P35908|K22E_HUMAN 1 1328.6321 97.07 84911 16083 2 1328.626414 665.3233 "Keratin, type II cytoskeletal 2 epidermal OS=Homo sapiens OX=9606 GN=KRT2 PE=1 SV=2" 4.03 2691.7 - 7.11E+06 - - - -4.2472 - 2.67 0.57 - 850.8 1 2 0 -0.0056 12 0 0 0 1.94E+08 1.99E+06 - - - 5.8333 0.9998 221125_WJC_METTL3_EV_vs_WT_F06.16088.16088.3 0.000254 Nov-44 K.NVQDAIADAEQR.G sp|P35908|K22E_HUMAN 1 1328.6321 6.01 84913 16088 3 1328.632529 443.8846 "Keratin, type II cytoskeletal 2 epidermal OS=Homo sapiens OX=9606 GN=KRT2 PE=1 SV=2" 4.03 2692.4 - 2.13E+06 - - - 0.3553 - 2.171 0.354 - 219.6 1 2 0 0.0005 12 0 0 0 3.72E+07 6.18E+06 - - - 4.6353 0.9953 221125_WJC_METTL3_EV_vs_WT_F06.16090.16090.3 0.0158 15/28 R.RRFEFDFR.D "sp|Q6Y7W6|GGYF2_HUMAN,tr|A0A7I2V3H7|A0A7I2V3H7_HUMAN,tr|I1E4Y6|I1E4Y6_HUMAN,tr|A0A7I2V516|A0A7I2V516_HUMAN,tr|A0A7I2V3H0|A0A7I2V3H0_HUMAN,tr|C9JHW1|C9JHW1_HUMAN,tr|A0A7I2V361|A0A7I2V361_HUMAN,tr|E7ESB6|E7ESB6_HUMAN" 8 1171.5887 3.58 84914 16090 3 1171.586276 391.5368 GRB10-interacting GYF protein 2 OS=Homo sapiens OX=9606 GN=GIGYF2 PE=1 SV=1 9.51 2692.6 - 2.45E+06 - - - -2.0485 - 2.051 0.266 - 499 1 2 1 -0.0024 8 0 0 0 5.14E+07 1.44E+07 - - - 3.7501 0.9933 221125_WJC_METTL3_EV_vs_WT_F06.16093.16093.3 4.42E-09 15/48 F.NDTFVHVTDLSGK[136.11].E "sp|P62263|RS14_HUMAN,tr|A0A2R8Y811|A0A2R8Y811_HUMAN,tr|E5RH77|E5RH77_HUMAN" 3 1439.7136 1.62 84915 16093 3 1439.709544 480.9118 40S ribosomal protein S14 OS=Homo sapiens OX=9606 GN=RPS14 PE=1 SV=3 5.21 2693 - 4.23E+06 - - - -2.8228 - 2.892 0.51 - 446.9 1 1 0 -0.0041 13 0 0 0 1.62E+08 9.98E+07 - - - 7.1041 0.9882 221125_WJC_METTL3_EV_vs_WT_F06.16099.16099.3 3.58E-08 14/48 F.NDTFVHVTDLSGK.E "sp|P62263|RS14_HUMAN,tr|A0A2R8Y811|A0A2R8Y811_HUMAN,tr|E5RH77|E5RH77_HUMAN" 3 1431.6994 1.62 84919 16099 3 1431.693126 478.2404 40S ribosomal protein S14 OS=Homo sapiens OX=9606 GN=RPS14 PE=1 SV=3 5.21 2693.7 - 5.97E+06 - - - -4.3878 - 2.813 0.605 - 384.4 1 1 0 -0.0063 13 0 0 0 1.62E+08 9.98E+07 - - - 8.0876 0.9999 221125_WJC_METTL3_EV_vs_WT_F06.16104.16104.3 1.20E-06 21/64 K.GTLNSNAAYEQSHFFNK.N sp|Q5T3J3|LRIF1_HUMAN 1 1926.886 2.04 84922 16104 3 1926.891451 643.3026 Ligand-dependent nuclear receptor-interacting factor 1 OS=Homo sapiens OX=9606 GN=LRIF1 PE=1 SV=1 6.75 2694.2 - 4.19E+06 - - - 2.8082 - 3.342 0.488 - 495 1 2 0 0.0054 17 0 0 0 1.35E+08 6.64E+07 - - - 7.0274 1 221125_WJC_METTL3_EV_vs_WT_F06.16105.16105.3 1.67E-06 18/40 R.K[136.11]LDPELHLDIK[136.11].V "sp|Q12905|ILF2_HUMAN,tr|B4DY09|B4DY09_HUMAN" 2 1335.7733 1.02 84923 16105 3 1335.771223 446.265 Interleukin enhancer-binding factor 2 OS=Homo sapiens OX=9606 GN=ILF2 PE=1 SV=2 5.38 2694.3 - 2.69E+06 - - - -1.5564 - 3.117 0.537 - 432.3 1 2 0 -0.0021 11 0 0 0 1.44E+08 1.42E+08 - - - 7.7561 0.9999 221125_WJC_METTL3_EV_vs_WT_F06.16106.16106.3 2.25E-06 20/40 R.KLDPELHLDIK.V "sp|Q12905|ILF2_HUMAN,tr|B4DY09|B4DY09_HUMAN" 2 1319.7449 1.02 84924 16106 3 1319.740583 440.9222 Interleukin enhancer-binding factor 2 OS=Homo sapiens OX=9606 GN=ILF2 PE=1 SV=2 5.38 2694.4 - 2.58E+06 - - - -3.2726 - 3.313 0.541 - 578.6 1 2 0 -0.0043 11 0 0 0 1.44E+08 1.42E+08 - - - 7.9733 0.9714 221125_WJC_METTL3_EV_vs_WT_F06.16111.16111.3 0.0302 17/60 Q.THISDTSVVLSMDNNR.N "sp|P48668|K2C6C_HUMAN,sp|P04259|K2C6B_HUMAN,sp|P02538|K2C6A_HUMAN" 3 1787.8472 122.66 84926 16111 3 1787.84336 596.9563 "Keratin, type II cytoskeletal 6C OS=Homo sapiens OX=9606 GN=KRT6C PE=1 SV=3" 5.18 2695 - 2.73E+06 - - - -2.1545 - 2.247 0.383 - 160 1 1 0 -0.0039 16 0 0 0 2.15E+08 1.75E+06 - - - 4.8863 1 221125_WJC_METTL3_EV_vs_WT_F06.16112.16112.3 2.46E-10 15/60 K.GDQENVHPDVMLVQPR[166.11].V "sp|Q14974|IMB1_HUMAN,tr|J3KTM9|J3KTM9_HUMAN" 2 1842.8922 0.96 84927 16112 3 1842.887219 615.3047 Importin subunit beta-1 OS=Homo sapiens OX=9606 GN=KPNB1 PE=1 SV=2 4.54 2695.1 - 1.20E+06 - - - -2.7034 - 3.075 0.642 - 290.9 1 2 0 -0.005 16 0 0 0 3.82E+07 3.97E+07 - - - 8.5785 1 221125_WJC_METTL3_EV_vs_WT_F06.16116.16116.3 2.85E-11 24/76 R.FSSC[160.03]GGGGGSFGAGGGFGSR.S sp|P04264|K2C1_HUMAN 1 1764.7274 999 84928 16116 3 1764.7298 589.2498 "Keratin, type II cytoskeletal 1 OS=Homo sapiens OX=9606 GN=KRT1 PE=1 SV=6" 8.25 2695.7 - 4.82E+06 - - - 1.3424 - 3.443 0.718 - 442.4 1 2 0 0.0024 20 0 0 0 2.58E+09 0.00E+00 - - - 9.5437 1 221125_WJC_METTL3_EV_vs_WT_F06.16117.16117.3 2.79E-05 14/64 K.GTLNSNAAYEQSHFFNK[136.11].N sp|Q5T3J3|LRIF1_HUMAN 1 1934.9002 1.98 84929 16117 3 1934.902608 645.974 Ligand-dependent nuclear receptor-interacting factor 1 OS=Homo sapiens OX=9606 GN=LRIF1 PE=1 SV=1 6.75 2695.8 - 3.60E+06 - - - 1.2238 - 3.174 0.456 - 316.7 1 2 0 0.0024 17 0 0 0 1.33E+08 6.69E+07 - - - 6.5412 0.9996 221125_WJC_METTL3_EV_vs_WT_F06.16121.16121.3 2.65E-06 17/48 K.NGDLDEVK[136.11]DYVAK[136.11].G "sp|P58546|MTPN_HUMAN,tr|C9JL85|C9JL85_HUMAN" 2 1480.738 0.67 84933 16121 3 1480.732686 494.5866 Myotrophin OS=Homo sapiens OX=9606 GN=MTPN PE=1 SV=2 4.23 2696.1 - 2.31E+06 - - - -3.6151 - 3.271 0.538 - 466.8 1 2 1 -0.0054 13 0 0 0 3.89E+07 5.84E+07 - - - 7.7498 0.9999 221125_WJC_METTL3_EV_vs_WT_F06.16124.16124.4 2.22E-07 20/108 R.GLLQDDAHPTLVTYADHSK[136.11].L "sp|Q86U44|MTA70_HUMAN,tr|F5H6D8|F5H6D8_HUMAN,tr|H0YFV6|H0YFV6_HUMAN,tr|B4DTN4|B4DTN4_HUMAN" 4 2088.0367 0.001 84934 16124 4 2088.030911 523.0165 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 5.13 2696.5 - 2.92E+06 - - - -2.7883 - 3.374 0.502 - 400.9 1 2 0 -0.0058 19 0 0 0 0.00E+00 9.46E+07 - - - 4.0052 0.9998 221125_WJC_METTL3_EV_vs_WT_F06.16125.16125.3 1.60E-08 22/64 R.KYGGISTASVDFEQPTR.D sp|P98175|RBM10_HUMAN 1 1854.9112 53.1 84935 16125 3 1854.901554 619.311 RNA-binding protein 10 OS=Homo sapiens OX=9606 GN=RBM10 PE=1 SV=3 6.07 2696.6 - 3.42E+06 - - - -5.1959 - 4.075 0.568 - 774.6 1 2 0 -0.0096 17 0 0 0 7.03E+07 1.32E+06 - - - 8.4191 0.9999 221125_WJC_METTL3_EV_vs_WT_F06.16126.16126.4 1.69E-09 20/96 R.LTEQLDVKEEQIEELKR.Q "sp|Q15643|TRIPB_HUMAN,tr|H0YJI2|H0YJI2_HUMAN,tr|H0YJ97|H0YJ97_HUMAN" 3 2099.111 1.17 84936 16126 4 2099.108776 525.785 Thyroid receptor-interacting protein 11 OS=Homo sapiens OX=9606 GN=TRIP11 PE=1 SV=3 4.42 2696.7 - 9.29E+06 - - - -1.0662 - 3.791 0.508 - 488.8 1 2 1 -0.0022 17 0 0 0 3.16E+08 2.70E+08 - - - 4.1097 0.9999 221125_WJC_METTL3_EV_vs_WT_F06.16127.16127.3 5.13E-08 22/56 R.ADTQTYQPYNKDWIK.E sp|P84090|ERH_HUMAN 1 1869.8897 1.79 84937 16127 3 1869.89286 624.3039 Enhancer of rudimentary homolog OS=Homo sapiens OX=9606 GN=ERH PE=1 SV=1 6 2696.8 - 3.55E+06 - - - 1.675 - 3.301 0.481 - 729.6 1 2 1 0.0031 15 0 0 0 1.30E+07 7.27E+06 - - - 7.018 0.9969 221125_WJC_METTL3_EV_vs_WT_F06.16128.16128.4 0.00153 Nov-72 R.INFDK[136.11]YHPGYFGK[136.11].V "sp|P46776|RL27A_HUMAN,tr|E9PLL6|E9PLL6_HUMAN" 2 1600.8009 0.72 84938 16128 4 1600.799276 401.2075 60S ribosomal protein L27a OS=Homo sapiens OX=9606 GN=RPL27A PE=1 SV=2 8.44 2696.8 - 2.41E+06 - - - -1.0232 - 2.143 0.304 - 68.2 1 2 1 -0.0016 13 0 0 0 3.86E+07 5.39E+07 - - - 2.1542 1 221125_WJC_METTL3_EV_vs_WT_F06.16129.16129.2 4.58E-07 15/32 K.ANELPQPPVPEPANAGK.R "sp|P78347|GTF2I_HUMAN,tr|A0A494C1K3|A0A494C1K3_HUMAN" 2 1727.8842 2.36 84939 16129 2 1727.878845 864.9494 General transcription factor II-I OS=Homo sapiens OX=9606 GN=GTF2I PE=1 SV=2 4.53 2697 - 1.23E+06 - - - -3.1275 - 2.492 0.624 - 516.3 1 2 0 -0.0054 17 0 0 0 1.27E+08 5.39E+07 - - - 5.893 0.9983 221125_WJC_METTL3_EV_vs_WT_F06.16133.16133.3 0.000797 13/56 R.ADTQTYQPYNK[136.11]DWIK[136.11].E sp|P84090|ERH_HUMAN 1 1885.9181 2.4 84941 16133 3 1885.910002 629.6467 Enhancer of rudimentary homolog OS=Homo sapiens OX=9606 GN=ERH PE=1 SV=1 6 2697.4 - 6.22E+06 - - - -4.3088 - 2.36 0.486 - 197.8 1 2 1 -0.0081 15 0 0 0 4.18E+10 1.74E+10 - - - 6.1967 0.9999 221125_WJC_METTL3_EV_vs_WT_F06.16134.16134.3 8.11E-06 20/64 R.LTEQLDVKEEQIEELKR.Q "sp|Q15643|TRIPB_HUMAN,tr|H0YJI2|H0YJI2_HUMAN,tr|H0YJ97|H0YJ97_HUMAN" 3 2099.111 1.36 84942 16134 3 2099.113656 700.7109 Thyroid receptor-interacting protein 11 OS=Homo sapiens OX=9606 GN=TRIP11 PE=1 SV=3 4.42 2697.4 - 3.59E+06 - - - 1.2586 - 4.425 0.524 - 732.9 1 2 1 0.0026 17 0 0 0 1.24E+08 9.14E+07 - - - 8.1386 0.9998 221125_WJC_METTL3_EV_vs_WT_F06.16138.16138.4 0.000194 17/72 R.INFDKYHPGYFGK.V "sp|P46776|RL27A_HUMAN,tr|E9PLL6|E9PLL6_HUMAN" 2 1584.7725 0.72 84944 16138 4 1584.770599 397.2004 60S ribosomal protein L27a OS=Homo sapiens OX=9606 GN=RPL27A PE=1 SV=2 8.44 2698 - 2.88E+06 - - - -1.2084 - 2.76 0.454 - 215.2 1 2 1 -0.0019 13 0 0 0 3.86E+07 5.39E+07 - - - 3.5535 1 221125_WJC_METTL3_EV_vs_WT_F06.16139.16139.3 1.77E-08 20/48 K.NGDLDEVKDYVAK.G "sp|P58546|MTPN_HUMAN,tr|C9JL85|C9JL85_HUMAN" 2 1464.7096 0.67 84945 16139 3 1464.7085 489.2438 Myotrophin OS=Homo sapiens OX=9606 GN=MTPN PE=1 SV=2 4.23 2698 - 2.56E+06 - - - -0.7776 - 3.494 0.649 - 651.4 1 2 1 -0.0011 13 0 0 0 3.89E+07 5.84E+07 - - - 9.1673 1 221125_WJC_METTL3_EV_vs_WT_F06.16140.16140.3 1.88E-09 22/60 R.DC[160.03]LADVDTK[136.11]PAYQNLR[166.11].Q "sp|Q96IK1|BOD1_HUMAN,sp|Q8NFC6|BD1L1_HUMAN" 2 1895.9166 5.34 84946 16140 3 1895.912504 632.9795 Biorientation of chromosomes in cell division protein 1 OS=Homo sapiens OX=9606 GN=BOD1 PE=1 SV=2 4.43 2698.2 - 2.10E+06 - - - -2.1773 - 3.777 0.617 - 462.1 1 2 0 -0.0041 16 0 0 0 6.54E+07 1.23E+07 - - - 8.8277 1 221125_WJC_METTL3_EV_vs_WT_F06.16146.16146.2 1.22E-07 16/28 R.ADTQTYQPYNKDWIK.E sp|P84090|ERH_HUMAN 1 1869.8897 2.4 84950 16146 2 1869.886719 935.9521 Enhancer of rudimentary homolog OS=Homo sapiens OX=9606 GN=ERH PE=1 SV=1 6 2698.9 - 2.27E+06 - - - -1.6092 - 3.16 0.617 - 686.6 1 2 1 -0.003 15 0 0 0 4.43E+09 1.84E+09 - - - 6.426 1 221125_WJC_METTL3_EV_vs_WT_F06.16149.16149.3 1.05E-08 15/64 R.IQTLPNQNQSQTQPLLK.T "sp|Q8IX12|CCAR1_HUMAN,tr|F5H2E6|F5H2E6_HUMAN,tr|F5H1H2|F5H1H2_HUMAN,tr|A0A0C4DGG8|A0A0C4DGG8_HUMAN,tr|F5H3E1|F5H3E1_HUMAN" 5 1950.0534 7.43 84951 16149 3 1950.048525 651.0251 Cell division cycle and apoptosis regulator protein 1 OS=Homo sapiens OX=9606 GN=CCAR1 PE=1 SV=2 8.75 2699.3 - 3.07E+06 - - - -2.5204 - 2.633 0.571 - 268.5 1 2 0 -0.0049 17 0 0 0 7.86E+07 1.06E+07 - - - 7.3505 0.9997 221125_WJC_METTL3_EV_vs_WT_F06.16150.16150.3 3.04E-05 19/64 R.AADEEAFEDNSEEYIRR.D sp|P55060|XPO2_HUMAN 1 2042.8817 0.99 84952 16150 3 2042.871695 681.9679 Exportin-2 OS=Homo sapiens OX=9606 GN=CSE1L PE=1 SV=3 4 2699.4 - 2.20E+06 - - - -4.9181 - 2.778 0.517 - 463.3 1 2 0 -0.01 17 0 0 0 1.86E+08 1.88E+08 - - - 6.8825 1 221125_WJC_METTL3_EV_vs_WT_F06.16153.16153.2 9.37E-06 19/28 R.ADTQTYQPYNK[136.11]DWIK[136.11].E sp|P84090|ERH_HUMAN 1 1885.9181 2.4 84955 16153 2 1885.921251 943.9663 Enhancer of rudimentary homolog OS=Homo sapiens OX=9606 GN=ERH PE=1 SV=1 6 2699.7 - 2.41E+06 - - - 1.656 - 3.418 0.57 - 960.9 1 2 1 0.0031 15 0 0 0 4.43E+09 1.84E+09 - - - 6.2717 1 221125_WJC_METTL3_EV_vs_WT_F06.16154.16154.2 3.53E-08 17/32 R.IQTLPNQNQSQTQPLLK.T "sp|Q8IX12|CCAR1_HUMAN,tr|F5H2E6|F5H2E6_HUMAN,tr|F5H1H2|F5H1H2_HUMAN,tr|A0A0C4DGG8|A0A0C4DGG8_HUMAN,tr|F5H3E1|F5H3E1_HUMAN" 5 1950.0534 999 84956 16154 2 1950.048981 976.034 Cell division cycle and apoptosis regulator protein 1 OS=Homo sapiens OX=9606 GN=CCAR1 PE=1 SV=2 8.75 2699.8 - 1.41E+06 - - - -2.2866 - 3.146 0.644 - 845.3 1 2 0 -0.0045 17 0 0 0 2.63E+07 0.00E+00 - - - 6.614 1 221125_WJC_METTL3_EV_vs_WT_F06.16156.16156.2 1.19E-08 17/24 K.HPDASVNFSEFSK[136.11].K "sp|P09429|HMGB1_HUMAN,tr|Q5T7C4|Q5T7C4_HUMAN" 2 1471.6823 0.11 84958 16156 2 1471.680031 736.8484 High mobility group protein B1 OS=Homo sapiens OX=9606 GN=HMGB1 PE=1 SV=3 5.32 2700.1 - 1.16E+06 - - - -1.5472 - 3.287 0.659 - 692.5 1 2 0 -0.0023 13 0 0 0 2.39E+07 2.22E+08 - - - 6.9618 1 221125_WJC_METTL3_EV_vs_WT_F06.16157.16157.2 2.58E-12 18/36 R.ESAEEAWGTEEAPAPAPAR.S sp|Q6QNY0|BL1S3_HUMAN 1 1967.8861 3.72 84959 16157 2 1967.882076 984.9503 Biogenesis of lysosome-related organelles complex 1 subunit 3 OS=Homo sapiens OX=9606 GN=BLOC1S3 PE=1 SV=1 3.98 2700.2 - 1.13E+06 - - - -2.0448 - 3.274 0.571 - 684.3 1 2 0 -0.004 19 0 0 0 2.78E+07 7.49E+06 - - - 6.173 1 221125_WJC_METTL3_EV_vs_WT_F06.16158.16158.2 1.96E-13 21/30 Q.THISDTSVVLSMDNNR.N "sp|P48668|K2C6C_HUMAN,sp|P04259|K2C6B_HUMAN,sp|P02538|K2C6A_HUMAN" 3 1787.8472 7.19 84960 16158 2 1787.848004 894.9309 "Keratin, type II cytoskeletal 6C OS=Homo sapiens OX=9606 GN=KRT6C PE=1 SV=3" 5.18 2700.4 - 840030 - - - 0.443 - 3.84 0.68 - 1119.5 1 1 0 0.0008 16 0 0 0 2.12E+07 2.95E+06 - - - 7.3711 1 221125_WJC_METTL3_EV_vs_WT_F06.16162.16162.3 5.22E-09 25/76 K.DILLQQQQQLGHGGPEAAPR.A sp|Q7Z5L9|I2BP2_HUMAN 1 2155.1134 1.61 84962 16162 3 2155.109906 719.3784 Interferon regulatory factor 2-binding protein 2 OS=Homo sapiens OX=9606 GN=IRF2BP2 PE=1 SV=2 5.32 2700.8 - 4.73E+06 - - - -1.6278 - 4.061 0.609 - 737.4 1 2 0 -0.0035 20 0 0 0 9.06E+08 5.63E+08 - - - 8.7287 1 221125_WJC_METTL3_EV_vs_WT_F06.16164.16164.3 3.44E-07 26/76 K.DILLQQQQQLGHGGPEAAPR[166.11].A sp|Q7Z5L9|I2BP2_HUMAN 1 2165.1217 1.61 84964 16164 3 2165.116934 722.7145 Interferon regulatory factor 2-binding protein 2 OS=Homo sapiens OX=9606 GN=IRF2BP2 PE=1 SV=2 5.32 2701 - 4.08E+06 - - - -2.1939 - 4.568 0.667 - 777.1 1 2 0 -0.0047 20 0 0 0 9.06E+08 5.63E+08 - - - 9.6604 0.9824 221125_WJC_METTL3_EV_vs_WT_F06.16170.16170.3 0.517 14/56 K.SLALDIDRDAEDQNR.Y "sp|Q9NYM9|BET1L_HUMAN,tr|A0A0C4DH16|A0A0C4DH16_HUMAN,tr|B8ZZS0|B8ZZS0_HUMAN,tr|E9PQJ6|E9PQJ6_HUMAN,tr|H7BXT7|H7BXT7_HUMAN" 5 1729.8231 0.4 84968 16170 3 1729.817504 577.615 BET1-like protein OS=Homo sapiens OX=9606 GN=BET1L PE=1 SV=1 4.04 2701.7 - 2.12E+06 - - - -3.2379 - 2.378 0.234 - 173 1 2 1 -0.0056 15 0 0 0 4.28E+07 1.07E+08 - - - 3.4077 1 221125_WJC_METTL3_EV_vs_WT_F06.16179.16179.3 1.59E-11 16/72 R.ESAEEAWGTEEAPAPAPAR.S sp|Q6QNY0|BL1S3_HUMAN 1 1967.8861 9.23 84975 16179 3 1967.8854 656.9693 Biogenesis of lysosome-related organelles complex 1 subunit 3 OS=Homo sapiens OX=9606 GN=BLOC1S3 PE=1 SV=1 3.98 2702.8 - 1.50E+06 - - - -0.3557 - 3.047 0.646 - 204 1 2 0 -0.0007 19 0 0 0 2.27E+07 2.46E+06 - - - 8.4793 0.9996 221125_WJC_METTL3_EV_vs_WT_F06.16182.16182.3 2.88E-08 17/52 R.HTLADNFNPVSEER.G "sp|P20645|MPRD_HUMAN,tr|H0YGT2|H0YGT2_HUMAN" 2 1627.759 0.74 84976 16182 3 1627.750042 543.5936 Cation-dependent mannose-6-phosphate receptor OS=Homo sapiens OX=9606 GN=M6PR PE=1 SV=1 4.65 2703.2 - 1.91E+06 - - - -5.5328 - 3.389 0.501 - 339.3 1 2 0 -0.009 14 0 0 0 1.32E+08 1.78E+08 - - - 7.3668 1 221125_WJC_METTL3_EV_vs_WT_F06.16186.16186.3 7.88E-07 17/60 K.FSVC[160.03]VLGDQQHC[160.03]DEAK[136.11].A sp|P62906|RL10A_HUMAN 1 1899.8335 0.91 84979 16186 3 1899.831362 634.2851 60S ribosomal protein L10a OS=Homo sapiens OX=9606 GN=RPL10A PE=1 SV=2 4.54 2703.7 - 1.43E+06 - - - -1.1164 - 3.479 0.571 - 381.1 1 2 0 -0.0021 16 0 0 0 3.13E+08 3.45E+08 - - - 8.1045 0.9857 221125_WJC_METTL3_EV_vs_WT_F06.16190.16190.2 2.89E-08 15/32 K.TAQALAQLAAQHSQSGS.T "sp|Q14157|UBP2L_HUMAN,tr|F8W726|F8W726_HUMAN" 2 1667.8227 - 84981 16190 2 1667.818731 834.9186 Ubiquitin-associated protein 2-like OS=Homo sapiens OX=9606 GN=UBAP2L PE=1 SV=2 6.4 2704.2 - 1.06E+06 - - - -2.3863 - 2.715 0.558 - 555.1 1 1 0 -0.004 17 0 0 0 - - - - - 5.6167 1 221125_WJC_METTL3_EV_vs_WT_F06.16191.16191.3 7.42E-08 16/48 K.HPDASVNFSEFSK.K "sp|P09429|HMGB1_HUMAN,tr|Q5T7C4|Q5T7C4_HUMAN" 2 1463.6681 0.18 84982 16191 3 1463.666698 488.8966 High mobility group protein B1 OS=Homo sapiens OX=9606 GN=HMGB1 PE=1 SV=3 5.32 2704.3 - 1.41E+06 - - - -0.9633 - 2.67 0.572 - 338.9 1 2 0 -0.0014 13 0 0 0 9.87E+07 5.58E+08 - - - 7.5795 0.9999 221125_WJC_METTL3_EV_vs_WT_F06.16196.16196.2 8.05E-07 17/32 R.ISIGGGSC[160.03]AISGGYGSR.A "sp|P48668|K2C6C_HUMAN,sp|P04259|K2C6B_HUMAN,sp|P02538|K2C6A_HUMAN" 3 1597.7519 999 84983 16196 2 1597.750316 799.8832 "Keratin, type II cytoskeletal 6C OS=Homo sapiens OX=9606 GN=KRT6C PE=1 SV=3" 8.22 2705.1 - 3.39E+06 - - - -0.9632 - 2.913 0.516 - 826.4 1 2 0 -0.0015 17 0 0 0 2.95E+08 0.00E+00 - - - 5.4803 1 221125_WJC_METTL3_EV_vs_WT_F06.16200.16200.2 8.80E-16 24/34 K.YVHYEIDAC[160.03]MDSEAPGSK[136.11].D "sp|Q86U44|MTA70_HUMAN,tr|H0YFV6|H0YFV6_HUMAN" 2 2078.8805 0 84986 16200 2 2079.876636 1040.4475 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 4.31 2705.5 - 2.05E+07 - - - 479.1733 - 4.296 0.783 - 1263.7 1 2 0 0.9961 18 0 0 0 4.01E+06 1.12E+09 - - - 8.0952 1 221125_WJC_METTL3_EV_vs_WT_F06.16206.16206.2 4.04E-08 16/22 T.QTYQPYNKDWIK.E sp|P84090|ERH_HUMAN 1 1582.778 999 84989 16206 2 1582.776784 792.3963 Enhancer of rudimentary homolog OS=Homo sapiens OX=9606 GN=ERH PE=1 SV=1 8.43 2706.2 - 1.57E+06 - - - -0.7638 - 2.858 0.541 - 846.1 1 1 1 -0.0012 12 0 0 0 3.58E+07 0.00E+00 - - - 5.7995 1 221125_WJC_METTL3_EV_vs_WT_F06.16208.16208.3 2.16E-08 17/68 K.YVHYEIDAC[160.03]MDSEAPGSK.D "sp|Q86U44|MTA70_HUMAN,tr|H0YFV6|H0YFV6_HUMAN" 2 2070.8663 0.02 84990 16208 3 2070.863871 691.296 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 4.31 2706.4 - 5.86E+06 - - - -1.1691 - 3.671 0.715 - 329 1 2 0 -0.0024 18 0 0 0 3.08E+08 1.30E+10 - - - 9.7492 0.9219 221125_WJC_METTL3_EV_vs_WT_F06.16209.16209.2 1.92E-06 15/20 Q.TYQPYNKDWIK.E sp|P84090|ERH_HUMAN 1 1454.7194 6.21 84991 16209 2 1454.718888 728.367 Enhancer of rudimentary homolog OS=Homo sapiens OX=9606 GN=ERH PE=1 SV=1 8.1 2706.5 - 2.57E+06 - - - -0.3623 - 2.086 0.51 - 564.2 1 1 1 -0.0005 11 0 0 0 5.75E+07 9.26E+06 - - - 4.7967 0.9999 221125_WJC_METTL3_EV_vs_WT_F06.16210.16210.3 0.000162 19/64 K.ANELPQPPVPEPANAGK.R "sp|P78347|GTF2I_HUMAN,tr|A0A494C1K3|A0A494C1K3_HUMAN" 2 1727.8842 3.16 84992 16210 3 1727.881251 576.9687 General transcription factor II-I OS=Homo sapiens OX=9606 GN=GTF2I PE=1 SV=2 4.53 2706.6 - 1.54E+06 - - - -1.7351 - 2.696 0.449 - 322.7 1 2 0 -0.003 17 0 0 0 7.38E+07 2.33E+07 - - - 6.0506 0.9996 221125_WJC_METTL3_EV_vs_WT_F06.16219.16219.4 0.000178 13/84 R.ADTQTYQPYNKDWIK.E sp|P84090|ERH_HUMAN 1 1869.8897 3.49 84996 16219 4 1869.889165 468.4797 Enhancer of rudimentary homolog OS=Homo sapiens OX=9606 GN=ERH PE=1 SV=1 6 2707.7 - 3.41E+06 - - - -0.3011 - 2.453 0.425 - 85.8 1 2 1 -0.0006 15 0 0 0 8.18E+07 2.34E+07 - - - 3.2461 1 221125_WJC_METTL3_EV_vs_WT_F06.16221.16221.3 4.01E-07 15/64 K.ANELPQPPVPEPANAGK[136.11].R "sp|P78347|GTF2I_HUMAN,tr|A0A494C1K3|A0A494C1K3_HUMAN" 2 1735.8984 3.17 84997 16221 3 1735.898581 579.6401 General transcription factor II-I OS=Homo sapiens OX=9606 GN=GTF2I PE=1 SV=2 4.53 2708 - 986176 - - - 0.076 - 2.757 0.443 - 232.7 1 2 0 0.0001 17 0 0 0 4.28E+07 1.35E+07 - - - 6.041 1 221125_WJC_METTL3_EV_vs_WT_F06.16223.16223.3 8.42E-06 16/52 R.HTLADNFNPVSEER[166.11].G "sp|P20645|MPRD_HUMAN,tr|H0YGT2|H0YGT2_HUMAN" 2 1637.7673 0.91 84998 16223 3 1637.765121 546.9297 Cation-dependent mannose-6-phosphate receptor OS=Homo sapiens OX=9606 GN=M6PR PE=1 SV=1 4.65 2708.2 - 4.92E+06 - - - -1.3415 - 3.155 0.555 - 316.4 1 2 0 -0.0022 14 0 0 0 1.32E+08 1.46E+08 - - - 7.7806 0.9986 221125_WJC_METTL3_EV_vs_WT_F06.16225.16225.3 8.23E-06 21/60 K.TGQPMINLYTDR[166.11]ETGK[136.11].L "sp|P35637|FUS_HUMAN,tr|H3BPE7|H3BPE7_HUMAN" 2 1840.9108 1 85000 16225 3 1840.920073 614.6442 RNA-binding protein FUS OS=Homo sapiens OX=9606 GN=FUS PE=1 SV=1 5.73 2708.4 - 2.06E+06 - - - 5.0274 - 3.558 0.484 - 725.2 1 2 1 0.0093 16 0 0 0 2.85E+08 2.85E+08 - - - 7.1902 0.9999 221125_WJC_METTL3_EV_vs_WT_F06.16226.16226.3 1.06E-06 15/48 K.QADLYISEGLHPR[166.11].L "sp|Q92526|TCPW_HUMAN,sp|P40227|TCPZ_HUMAN" 2 1507.7659 0.38 85001 16226 3 1507.762094 503.5959 T-complex protein 1 subunit zeta-2 OS=Homo sapiens OX=9606 GN=CCT6B PE=1 SV=5 5.32 2708.5 - 1.29E+06 - - - -2.4991 - 2.521 0.468 - 276.6 1 2 0 -0.0038 13 0 0 0 1.29E+07 3.41E+07 - - - 6.2637 0.9999 221125_WJC_METTL3_EV_vs_WT_F06.16230.16230.4 2.01E-09 24/84 K.VKELVEFAQDDDRLR.E sp|Q14677|EPN4_HUMAN 1 1831.9428 1.49 85003 16230 4 1831.940833 458.993 Clathrin interactor 1 OS=Homo sapiens OX=9606 GN=CLINT1 PE=1 SV=1 4.44 2709 - 2.77E+06 - - - -1.0885 - 3.716 0.528 - 701.5 1 2 2 -0.002 15 0 0 0 2.25E+08 1.51E+08 - - - 4.2908 0.9994 221125_WJC_METTL3_EV_vs_WT_F06.16234.16234.4 1.73E-05 16/84 K.VK[136.11]ELVEFAQDDDR[166.11]LR[166.11].E sp|Q14677|EPN4_HUMAN 1 1859.9736 1.49 85005 16234 4 1859.968673 466.0007 Clathrin interactor 1 OS=Homo sapiens OX=9606 GN=CLINT1 PE=1 SV=1 4.44 2709.5 - 3.43E+06 - - - -2.6312 - 2.786 0.448 - 323.5 1 2 2 -0.0049 15 0 0 0 2.25E+08 1.51E+08 - - - 3.4907 0.9999 221125_WJC_METTL3_EV_vs_WT_F06.16235.16235.2 9.11E-07 15/32 K.ANELPQPPVPEPANAGK[136.11].R "sp|P78347|GTF2I_HUMAN,tr|A0A494C1K3|A0A494C1K3_HUMAN" 2 1735.8984 2.37 85006 16235 2 1735.898731 868.9565 General transcription factor II-I OS=Homo sapiens OX=9606 GN=GTF2I PE=1 SV=2 4.53 2709.7 - 1.23E+06 - - - 0.1625 - 2.381 0.543 - 522.2 1 2 0 0.0003 17 0 0 0 1.31E+08 5.55E+07 - - - 5.1843 0.9999 221125_WJC_METTL3_EV_vs_WT_F06.16241.16241.3 4.90E-06 16/56 K.VKELVEFAQDDDRLR.E sp|Q14677|EPN4_HUMAN 1 1831.9428 1.3 85010 16241 3 1831.945876 611.6549 Clathrin interactor 1 OS=Homo sapiens OX=9606 GN=CLINT1 PE=1 SV=1 4.44 2710.3 - 6.35E+06 - - - 1.6644 - 2.858 0.54 - 249.9 1 2 2 0.003 15 0 0 0 2.16E+08 1.65E+08 - - - 7.2998 0.9998 221125_WJC_METTL3_EV_vs_WT_F06.16242.16242.3 9.93E-05 16/44 R.MSVEADINGLRR.V "sp|P02533|K1C14_HUMAN,sp|P08727|K1C19_HUMAN,tr|C9JM50|C9JM50_HUMAN,tr|K7EMS3|K7EMS3_HUMAN" 4 1359.6929 65.87 85011 16242 3 1359.688289 454.2382 "Keratin, type I cytoskeletal 14 OS=Homo sapiens OX=9606 GN=KRT14 PE=1 SV=4" 5.82 2710.4 - 4.02E+06 - - - -3.3787 - 2.767 0.409 - 435.3 1 2 0 -0.0046 12 0 0 0 5.27E+07 8.00E+05 - - - 5.9198 0.9999 221125_WJC_METTL3_EV_vs_WT_F06.16243.16243.3 1.49E-07 18/60 K.TGQPMINLYTDRETGK.L "sp|P35637|FUS_HUMAN,tr|H3BPE7|H3BPE7_HUMAN" 2 1822.8883 1 85012 16243 3 1822.887169 608.6367 RNA-binding protein FUS OS=Homo sapiens OX=9606 GN=FUS PE=1 SV=1 5.73 2710.4 - 4.98E+06 - - - -0.6468 - 3.639 0.544 - 506.1 1 2 1 -0.0012 16 0 0 0 2.86E+08 2.85E+08 - - - 7.9191 1 221125_WJC_METTL3_EV_vs_WT_F06.16244.16244.3 1.86E-06 Dec-32 R.VVHIMDFQR.G "sp|P43243|MATR3_HUMAN,tr|D6RE02|D6RE02_HUMAN,tr|B3KM87|B3KM87_HUMAN,tr|A8MXP9|A8MXP9_HUMAN,tr|D6RAY2|D6RAY2_HUMAN,tr|D6R991|D6R991_HUMAN,tr|A0A0R4J2E8|A0A0R4J2E8_HUMAN,tr|D6RAM9|D6RAM9_HUMAN,tr|D6RIA2|D6RIA2_HUMAN,tr|H0Y8T4|H0Y8T4_HUMAN,tr|D6REM6|D6REM6_HUMAN,tr|D6RBI2|D6RBI2_HUMAN" 12 1143.5859 1.13 85013 16244 3 1143.583761 382.2026 Matrin-3 OS=Homo sapiens OX=9606 GN=MATR3 PE=1 SV=2 6.71 2710.5 - 2.82E+06 - - - -1.8696 - 2.068 0.522 - 366.2 1 2 0 -0.0021 9 0 0 0 4.92E+07 4.37E+07 - - - 6.549 0.9999 221125_WJC_METTL3_EV_vs_WT_F06.16249.16249.3 7.04E-08 18/56 K.VK[136.11]ELVEFAQDDDR[166.11]LR[166.11].E sp|Q14677|EPN4_HUMAN 1 1859.9736 1.31 85015 16249 3 1859.974184 620.9985 Clathrin interactor 1 OS=Homo sapiens OX=9606 GN=CLINT1 PE=1 SV=1 4.44 2711.1 - 6.70E+06 - - - 0.3317 - 3.377 0.546 - 339.7 1 2 2 0.0006 15 0 0 0 2.15E+08 1.65E+08 - - - 7.8028 0.9875 221125_WJC_METTL3_EV_vs_WT_F06.16251.16251.3 0.232 Jul-44 R.GQPIYIQFSNHK.E "sp|P26599|PTBP1_HUMAN,tr|A0A6Q8PEX4|A0A6Q8PEX4_HUMAN,tr|A0A0U1RRM4|A0A0U1RRM4_HUMAN,tr|A6NLN1|A6NLN1_HUMAN,tr|K7EKJ7|K7EKJ7_HUMAN,tr|K7ES59|K7ES59_HUMAN,tr|A0A7I2V4H6|A0A7I2V4H6_HUMAN,tr|A0A7I2V621|A0A7I2V621_HUMAN" 8 1430.7306 0.93 85017 16251 3 1430.728793 477.9175 Polypyrimidine tract-binding protein 1 OS=Homo sapiens OX=9606 GN=PTBP1 PE=1 SV=1 8.6 2711.3 - 3.52E+06 - - - -1.2972 - 1.469 0.193 - 63.4 1 2 0 -0.0019 12 0 0 0 4.49E+08 4.81E+08 - - - 1.7572 0.983 221125_WJC_METTL3_EV_vs_WT_F06.16252.16252.3 0.0315 13/48 R.EGNHKPIDYLNPP.K "sp|P05089|ARGI1_HUMAN,tr|A0A5F9ZGN6|A0A5F9ZGN6_HUMAN,tr|A0A5F9ZH78|A0A5F9ZH78_HUMAN" 3 1492.731 143.31 85018 16252 3 1492.730636 498.5843 Arginase-1 OS=Homo sapiens OX=9606 GN=ARG1 PE=1 SV=2 5.32 2711.4 - 1.76E+06 - - - -0.2727 - 2.341 0.349 - 163 1 1 0 -0.0004 13 0 0 0 9.13E+07 6.37E+05 - - - 4.7371 1 221125_WJC_METTL3_EV_vs_WT_F06.16253.16253.3 2.36E-07 22/68 K.MEK[136.11]PPAPPSLPAGPPGVK[136.11].R sp|Q15428|SF3A2_HUMAN 1 1784.983 0.65 85019 16253 3 1784.981828 596.0016 Splicing factor 3A subunit 2 OS=Homo sapiens OX=9606 GN=SF3A2 PE=1 SV=2 8.35 2711.5 - 1.64E+06 - - - -0.6437 - 2.692 0.495 - 235.9 1 2 0 -0.0011 18 0 0 0 3.10E+07 4.75E+07 - - - 6.5244 1 221125_WJC_METTL3_EV_vs_WT_F06.16259.16259.2 1.50E-07 16/28 R.SGDSEVYQLGDVSQK.T "sp|Q04837|SSBP_HUMAN,tr|C9K0U8|C9K0U8_HUMAN,tr|A0A0G2JLD8|A0A0G2JLD8_HUMAN,tr|E7EUY5|E7EUY5_HUMAN" 4 1610.7424 1.45 85023 16259 2 1610.742601 806.3785 "Single-stranded DNA-binding protein, mitochondrial OS=Homo sapiens OX=9606 GN=SSBP1 PE=1 SV=1" 4.03 2712.2 - 6.25E+06 - - - 0.1279 - 3.049 0.674 - 1032.2 1 2 0 0.0002 15 0 0 0 8.57E+08 5.92E+08 - - - 6.7599 1 221125_WJC_METTL3_EV_vs_WT_F06.16260.16260.3 5.82E-07 13/56 R.SGDSEVYQLGDVSQK[136.11].T "sp|Q04837|SSBP_HUMAN,tr|C9K0U8|C9K0U8_HUMAN,tr|A0A0G2JLD8|A0A0G2JLD8_HUMAN,tr|E7EUY5|E7EUY5_HUMAN" 4 1618.7566 1.53 85024 16260 3 1618.754945 540.5928 "Single-stranded DNA-binding protein, mitochondrial OS=Homo sapiens OX=9606 GN=SSBP1 PE=1 SV=1" 4.03 2712.3 - 1.80E+06 - - - -1.0193 - 2.512 0.545 - 160.7 1 2 0 -0.0017 15 0 0 0 2.09E+08 1.37E+08 - - - 7.0192 0.9996 221125_WJC_METTL3_EV_vs_WT_F06.16265.16265.3 1.26E-06 17/64 K.GESQTDIEITR[166.11]EEDFTR[166.11].L "sp|P49368|TCPG_HUMAN,tr|B4DUR8|B4DUR8_HUMAN" 2 2044.9452 0.17 85029 16265 3 2044.945128 682.6557 T-complex protein 1 subunit gamma OS=Homo sapiens OX=9606 GN=CCT3 PE=1 SV=4 4.08 2712.8 - 1.24E+06 - - - -0.0513 - 2.406 0.417 - 358.7 1 2 1 -0.0001 17 0 0 0 7.89E+06 4.52E+07 - - - 5.4071 0.9946 221125_WJC_METTL3_EV_vs_WT_F06.16266.16266.3 4.46E-08 22/80 R.AGAPGALSPSYDGGLHGLQSK.L "sp|P15923|TFE2_HUMAN,tr|K7ENH8|K7ENH8_HUMAN,tr|X6REB3|X6REB3_HUMAN,tr|A0A0A0MRB7|A0A0A0MRB7_HUMAN" 4 1981.9858 13.47 85030 16266 3 1982.99756 661.6692 Transcription factor E2-alpha OS=Homo sapiens OX=9606 GN=TCF3 PE=1 SV=1 6.79 2712.9 - 1.17E+06 - - - 510.5011 - 3.248 0.539 - 232.8 1 2 0 1.0118 21 0 0 0 1.64E+07 1.22E+06 - - - 7.0933 0.9958 221125_WJC_METTL3_EV_vs_WT_F06.16271.16271.3 0.0445 Sep-44 R.GQPIYIQFSNHK[136.11].E "sp|P26599|PTBP1_HUMAN,tr|A0A6Q8PEX4|A0A6Q8PEX4_HUMAN,tr|A0A0U1RRM4|A0A0U1RRM4_HUMAN,tr|A6NLN1|A6NLN1_HUMAN,tr|K7EKJ7|K7EKJ7_HUMAN,tr|K7ES59|K7ES59_HUMAN,tr|A0A7I2V4H6|A0A7I2V4H6_HUMAN,tr|A0A7I2V621|A0A7I2V621_HUMAN" 8 1438.7448 0.93 85033 16271 3 1438.742429 480.5889 Polypyrimidine tract-binding protein 1 OS=Homo sapiens OX=9606 GN=PTBP1 PE=1 SV=1 8.6 2713.5 - 1.19E+07 - - - -1.682 - 1.636 0.241 - 86.1 1 2 0 -0.0024 12 0 0 0 4.49E+08 4.81E+08 - - - 2.5907 1 221125_WJC_METTL3_EV_vs_WT_F06.16272.16272.3 2.32E-06 Nov-32 R.VVHIMDFQR[166.11].G "sp|P43243|MATR3_HUMAN,tr|D6RE02|D6RE02_HUMAN,tr|B3KM87|B3KM87_HUMAN,tr|A8MXP9|A8MXP9_HUMAN,tr|D6RAY2|D6RAY2_HUMAN,tr|D6R991|D6R991_HUMAN,tr|A0A0R4J2E8|A0A0R4J2E8_HUMAN,tr|D6RAM9|D6RAM9_HUMAN,tr|D6RIA2|D6RIA2_HUMAN,tr|H0Y8T4|H0Y8T4_HUMAN,tr|D6REM6|D6REM6_HUMAN,tr|D6RBI2|D6RBI2_HUMAN" 12 1153.5942 1.13 85034 16272 3 1153.59266 385.5387 Matrin-3 OS=Homo sapiens OX=9606 GN=MATR3 PE=1 SV=2 6.71 2713.6 - 2.20E+06 - - - -1.3081 - 2.101 0.495 - 283.6 1 2 0 -0.0015 9 0 0 0 4.92E+07 4.37E+07 - - - 6.2958 0.9959 221125_WJC_METTL3_EV_vs_WT_F06.16277.16277.3 0.0021 Dec-40 K.NMSVHLSPC[160.03]FR.D "sp|P62280|RS11_HUMAN,tr|M0R1H5|M0R1H5_HUMAN,tr|M0QZC5|M0QZC5_HUMAN" 3 1346.6224 0.79 85039 16277 3 1346.628239 449.8814 40S ribosomal protein S11 OS=Homo sapiens OX=9606 GN=RPS11 PE=1 SV=3 8.26 2714.2 - 826223 - - - 4.365 - 2.201 0.29 - 227.9 1 2 0 0.0059 11 0 0 0 9.86E+06 1.24E+07 - - - 4.0127 0.9972 221125_WJC_METTL3_EV_vs_WT_F06.16280.16280.2 5.66E-07 15/30 K.TGQPMINLYTDR[166.11]ETGK[136.11].L "sp|P35637|FUS_HUMAN,tr|H3BPE7|H3BPE7_HUMAN" 2 1840.9108 1.04 85042 16280 2 1840.906454 921.4627 RNA-binding protein FUS OS=Homo sapiens OX=9606 GN=FUS PE=1 SV=1 5.73 2714.6 - 441217 - - - -2.3706 - 2.476 0.575 - 522.2 1 2 1 -0.0044 16 0 0 0 4.28E+06 4.11E+06 - - - 5.5156 1 221125_WJC_METTL3_EV_vs_WT_F06.16282.16282.3 1.86E-05 15/48 K.HPDASVNFSEFSK[136.11].K "sp|P09429|HMGB1_HUMAN,tr|Q5T7C4|Q5T7C4_HUMAN" 2 1471.6823 0.18 85043 16282 3 1471.682618 491.568 High mobility group protein B1 OS=Homo sapiens OX=9606 GN=HMGB1 PE=1 SV=3 5.32 2714.8 - 6.46E+06 - - - 0.2106 - 2.793 0.584 - 334.6 1 2 0 0.0003 13 0 0 0 1.02E+08 5.68E+08 - - - 7.8357 1 221125_WJC_METTL3_EV_vs_WT_F06.16284.16284.2 3.52E-08 16/28 R.SGDSEVYQLGDVSQK[136.11].T "sp|Q04837|SSBP_HUMAN,tr|C9K0U8|C9K0U8_HUMAN,tr|A0A0G2JLD8|A0A0G2JLD8_HUMAN,tr|E7EUY5|E7EUY5_HUMAN" 4 1618.7566 1.45 85044 16284 2 1618.755298 810.3856 "Single-stranded DNA-binding protein, mitochondrial OS=Homo sapiens OX=9606 GN=SSBP1 PE=1 SV=1" 4.03 2715 - 2.22E+07 - - - -0.8012 - 3.263 0.702 - 944.6 1 2 0 -0.0013 15 0 0 0 8.57E+08 5.92E+08 - - - 7.1332 0.9999 221125_WJC_METTL3_EV_vs_WT_F06.16286.16286.3 0.000162 13/60 K.FSVC[160.03]VLGDQQHC[160.03]DEAK.A sp|P62906|RL10A_HUMAN 1 1891.8193 0.91 85046 16286 3 1891.817142 631.6137 60S ribosomal protein L10a OS=Homo sapiens OX=9606 GN=RPL10A PE=1 SV=2 4.54 2715.1 - 2.81E+06 - - - -1.1317 - 2.219 0.47 - 228 1 2 0 -0.0021 16 0 0 0 3.14E+08 3.45E+08 - - - 5.8246 1 221125_WJC_METTL3_EV_vs_WT_F06.16293.16293.3 1.77E-06 15/64 K.LHEQLTESEQAAQC[160.03]YIK[136.11].Y sp|Q9UJX2|CDC23_HUMAN 1 2054.9823 1.72 85053 16293 3 2054.977552 686.0014 Cell division cycle protein 23 homolog OS=Homo sapiens OX=9606 GN=CDC23 PE=1 SV=3 4.75 2716 - 823332 - - - -2.2886 - 3.141 0.567 - 380.4 1 2 0 -0.0047 17 0 0 0 2.12E+07 1.23E+07 - - - 7.7516 0.9972 221125_WJC_METTL3_EV_vs_WT_F06.16294.16294.3 0.000124 13/56 K.K[136.11]GWLDQEDQEAPLQK[136.11].G "sp|Q8IWC1|MA7D3_HUMAN,tr|A0A0A0MRP0|A0A0A0MRP0_HUMAN" 2 1799.9025 2.12 85054 16294 3 1799.896391 600.9748 MAP7 domain-containing protein 3 OS=Homo sapiens OX=9606 GN=MAP7D3 PE=1 SV=2 4.32 2716.1 - 769085 - - - -3.3818 - 2.459 0.256 - 221.1 1 2 0 -0.0061 15 0 0 0 1.67E+07 7.89E+06 - - - 3.7403 0.9999 221125_WJC_METTL3_EV_vs_WT_F06.16298.16298.4 4.14E-09 26/90 K.FILAPAKQEDEWDKPR.L sp|P13674|P4HA1_HUMAN 1 1941.9949 1.69 85056 16298 4 1941.994497 486.506 Prolyl 4-hydroxylase subunit alpha-1 OS=Homo sapiens OX=9606 GN=P4HA1 PE=1 SV=2 4.78 2716.7 - 1.91E+06 - - - -0.188 - 3.614 0.596 - 634.3 1 2 1 -0.0004 16 0 0 0 6.18E+07 3.66E+07 - - - 4.8661 1 221125_WJC_METTL3_EV_vs_WT_F06.16301.16301.2 1.78E-05 13/24 R.FSGSGSGTDFTLK.L "sp|A2NJV5|KV229_HUMAN,sp|A0A087WW87|KV240_HUMAN,sp|P06310|KV230_HUMAN,sp|A0A075B6S2|KVD29_HUMAN,sp|P01614|KVD40_HUMAN,sp|P01615|KVD28_HUMAN,sp|A0A075B6S6|KVD30_HUMAN,sp|A0A075B6P5|KV228_HUMAN,sp|A0A0A0MRZ7|KVD26_HUMAN" 9 1302.6092 15279.56 85059 16301 2 1302.610721 652.3119 Immunoglobulin kappa variable 2-29 OS=Homo sapiens OX=9606 GN=IGKV2-29 PE=3 SV=2 5.84 2716.8 - 4.08E+06 - - - 1.1707 - 2.704 0.643 - 323.4 1 2 0 0.0015 13 0 0 0 2.53E+09 1.66E+05 - - - 6.3427 0.9995 221125_WJC_METTL3_EV_vs_WT_F06.16303.16303.3 9.16E-05 17/56 R.R[166.11]GEAHLAVNDFELAR[166.11].A sp|Q02790|FKBP4_HUMAN 1 1716.8811 1.04 85061 16303 3 1716.872931 573.301 Peptidyl-prolyl cis-trans isomerase FKBP4 OS=Homo sapiens OX=9606 GN=FKBP4 PE=1 SV=3 5.45 2717 - 1.58E+06 - - - -4.733 - 3.083 0.427 - 431.6 1 2 0 -0.0081 15 0 0 0 2.55E+07 2.44E+07 - - - 6.2363 0.9999 221125_WJC_METTL3_EV_vs_WT_F06.16304.16304.4 2.65E-07 19/84 R.R[166.11]GEAHLAVNDFELAR[166.11].A sp|Q02790|FKBP4_HUMAN 1 1716.8811 2.32 85062 16304 4 1716.879883 430.2275 Peptidyl-prolyl cis-trans isomerase FKBP4 OS=Homo sapiens OX=9606 GN=FKBP4 PE=1 SV=3 5.45 2717.1 - 842195 - - - -0.6838 - 3.205 0.398 - 329.9 1 2 0 -0.0012 15 0 0 0 1.58E+07 6.80E+06 - - - 3.1066 1 221125_WJC_METTL3_EV_vs_WT_F06.16305.16305.2 8.30E-11 15/32 K.ETDQTETVSVQSSVLGK[136.11].G "sp|Q8NEM7|SP20H_HUMAN,tr|B4E2D5|B4E2D5_HUMAN,tr|R4GND2|R4GND2_HUMAN,tr|H7C5F9|H7C5F9_HUMAN,tr|F6S7C4|F6S7C4_HUMAN" 5 1814.8989 1.36 85063 16305 2 1814.890935 908.4567 Transcription factor SPT20 homolog OS=Homo sapiens OX=9606 GN=SUPT20H PE=1 SV=2 4.14 2717.3 - 543581 - - - -4.3903 - 3.267 0.712 - 597.8 1 2 0 -0.008 17 0 0 0 1.02E+07 7.45E+06 - - - 7.2079 1 221125_WJC_METTL3_EV_vs_WT_F06.16307.16307.2 3.06E-12 16/38 R.FSSC[160.03]GGGGGSFGAGGGFGSR.S sp|P04264|K2C1_HUMAN 1 1764.7274 999 85064 16307 2 1764.725666 883.371 "Keratin, type II cytoskeletal 1 OS=Homo sapiens OX=9606 GN=KRT1 PE=1 SV=6" 8.25 2717.5 - 6.78E+06 - - - -1.0002 - 3.602 0.792 - 704 1 2 0 -0.0018 20 0 0 0 1.38E+08 0.00E+00 - - - 8.0408 1 221125_WJC_METTL3_EV_vs_WT_F06.16309.16309.3 4.83E-08 13/56 R.SGDSEVYQLGDVSQK.T "sp|Q04837|SSBP_HUMAN,tr|C9K0U8|C9K0U8_HUMAN,tr|A0A0G2JLD8|A0A0G2JLD8_HUMAN,tr|E7EUY5|E7EUY5_HUMAN" 4 1610.7424 1.53 85065 16309 3 1610.741987 537.9214 "Single-stranded DNA-binding protein, mitochondrial OS=Homo sapiens OX=9606 GN=SSBP1 PE=1 SV=1" 4.03 2717.7 - 1.67E+07 - - - -0.2533 - 2.209 0.597 - 157.8 1 2 0 -0.0004 15 0 0 0 2.10E+08 1.37E+08 - - - 7.2639 1 221125_WJC_METTL3_EV_vs_WT_F06.16315.16315.3 2.00E-10 21/60 K.FILAPAKQEDEWDKPR.L sp|P13674|P4HA1_HUMAN 1 1941.9949 2.11 85071 16315 3 1941.992411 648.3389 Prolyl 4-hydroxylase subunit alpha-1 OS=Homo sapiens OX=9606 GN=P4HA1 PE=1 SV=2 4.78 2718.2 - 1.02E+06 - - - -1.2621 - 3.612 0.642 - 570.7 1 2 1 -0.0025 16 0 0 0 2.53E+07 1.20E+07 - - - 8.9922 0.999 221125_WJC_METTL3_EV_vs_WT_F06.16316.16316.3 0.00296 Dec-48 K.GIHPTIISESFQK[136.11].A sp|P50991|TCPD_HUMAN 1 1463.7864 0.19 85072 16316 3 1463.785995 488.9361 T-complex protein 1 subunit delta OS=Homo sapiens OX=9606 GN=CCT4 PE=1 SV=4 6.75 2718.4 - 907002 - - - -0.2623 - 1.921 0.269 - 153 1 2 0 -0.0004 13 0 0 0 6.06E+06 3.17E+07 - - - 3.309 0.9908 221125_WJC_METTL3_EV_vs_WT_F06.16321.16321.2 1.39E-07 13/18 Q.PIYIQFSNHK[136.11].E "sp|P26599|PTBP1_HUMAN,tr|A0A6Q8PEX4|A0A6Q8PEX4_HUMAN,tr|A0A0U1RRM4|A0A0U1RRM4_HUMAN,tr|A6NLN1|A6NLN1_HUMAN,tr|K7EKJ7|K7EKJ7_HUMAN,tr|K7ES59|K7ES59_HUMAN,tr|A0A7I2V4H6|A0A7I2V4H6_HUMAN,tr|A0A7I2V621|A0A7I2V621_HUMAN" 8 1253.6648 1.08 85075 16321 2 1253.663976 627.8397 Polypyrimidine tract-binding protein 1 OS=Homo sapiens OX=9606 GN=PTBP1 PE=1 SV=1 9.01 2719 - 2.21E+06 - - - -0.6629 - 2.312 0.429 - 499.7 1 1 0 -0.0008 10 0 0 0 5.81E+07 5.38E+07 - - - 4.5488 1 221125_WJC_METTL3_EV_vs_WT_F06.16323.16323.3 3.80E-09 23/64 R.VR[166.11]PC[160.03]VVYGGADIGQQIR[166.11].D "sp|O00571|DDX3X_HUMAN,sp|O15523|DDX3Y_HUMAN,tr|A0A2R8YFR4|A0A2R8YFR4_HUMAN,tr|A0A2R8YCW1|A0A2R8YCW1_HUMAN,tr|A0A2R8YDH3|A0A2R8YDH3_HUMAN,tr|A0A2R8YDT5|A0A2R8YDT5_HUMAN,tr|A0A2R8Y645|A0A2R8Y645_HUMAN,tr|A0A2R8YF78|A0A2R8YF78_HUMAN,tr|A0A0D9SFB3|A0A0D9SFB3_HUMAN,tr|A0A2R8YFS5|A0A2R8YFS5_HUMAN,tr|A0A0D9SF53|A0A0D9SF53_HUMAN,tr|A0A2R8Y5G6|A0A2R8Y5G6_HUMAN,tr|A0A2R8Y7T2|A0A2R8Y7T2_HUMAN,tr|A0A0D9SG12|A0A0D9SG12_HUMAN,tr|F6S8Q4|F6S8Q4_HUMAN,tr|A0A2U3TZJ9|A0A2U3TZJ9_HUMAN,tr|A0A2R8Y4A4|A0A2R8Y4A4_HUMAN" 17 1906.995 0.17 85077 16323 3 1906.999449 636.6723 ATP-dependent RNA helicase DDX3X OS=Homo sapiens OX=9606 GN=DDX3X PE=1 SV=3 8.19 2719.2 - 1.04E+06 - - - 2.3115 - 4.621 0.59 - 772.4 1 2 0 0.0044 17 0 0 0 1.71E+06 9.80E+06 - - - 8.9835 0.9999 221125_WJC_METTL3_EV_vs_WT_F06.16328.16328.3 5.56E-09 14/56 R.SEADSDKNATILELR.S sp|P15924|DESP_HUMAN 1 1660.8268 6.19 85080 16328 3 1660.827215 554.6162 Desmoplakin OS=Homo sapiens OX=9606 GN=DSP PE=1 SV=3 4.32 2719.9 - 1.01E+07 - - - 0.2535 - 2.632 0.614 - 281.5 1 2 1 0.0004 15 0 0 0 1.72E+08 2.77E+07 - - - 7.9106 0.9999 221125_WJC_METTL3_EV_vs_WT_F06.16330.16330.4 2.51E-09 24/90 K.FILAPAK[136.11]QEDEWDK[136.11]PR[166.11].L sp|P13674|P4HA1_HUMAN 1 1968.0315 1.7 85082 16330 4 1968.029926 493.0152 Prolyl 4-hydroxylase subunit alpha-1 OS=Homo sapiens OX=9606 GN=P4HA1 PE=1 SV=2 4.78 2720.1 - 3.00E+06 - - - -0.816 - 3.682 0.582 - 570.4 1 2 1 -0.0016 16 0 0 0 6.18E+07 3.63E+07 - - - 4.7504 1 221125_WJC_METTL3_EV_vs_WT_F06.16331.16331.3 7.48E-09 15/56 R.TGFSTSPESPYTHWK.Q "sp|Q99873|ANM1_HUMAN,tr|E9PKG1|E9PKG1_HUMAN" 2 1723.7842 0.96 85083 16331 3 1723.78305 575.602 Protein arginine N-methyltransferase 1 OS=Homo sapiens OX=9606 GN=PRMT1 PE=1 SV=3 6.41 2720.1 - 2.31E+06 - - - -0.6677 - 3.295 0.487 - 226.1 1 2 0 -0.0012 15 0 0 0 3.92E+07 4.07E+07 - - - 7.0807 0.9999 221125_WJC_METTL3_EV_vs_WT_F06.16337.16337.3 4.57E-07 15/88 R.EGPGSEPDSQVDGGLSGASLGEK[136.11].K "sp|Q5JSZ5|PRC2B_HUMAN,tr|A0A804HKC3|A0A804HKC3_HUMAN,tr|A0A804HJR4|A0A804HJR4_HUMAN" 3 2179.9961 1.21 85089 16337 3 2180.003627 727.6726 Protein PRRC2B OS=Homo sapiens OX=9606 GN=PRRC2B PE=1 SV=2 3.83 2720.9 - 804408 - - - 3.4752 - 2.991 0.507 - 196.7 1 2 0 0.0076 23 0 0 0 4.60E+07 3.81E+07 - - - 6.7607 0.9997 221125_WJC_METTL3_EV_vs_WT_F06.16338.16338.4 0.000111 14/78 R.LHPC[160.03]PPPDFFRPC[160.03]R.L "sp|Q9H6R4|NOL6_HUMAN,tr|A0A0A0MRW6|A0A0A0MRW6_HUMAN" 2 1794.8447 0.9 85090 16338 4 1794.842268 449.7184 Nucleolar protein 6 OS=Homo sapiens OX=9606 GN=NOL6 PE=1 SV=2 8.08 2721 - 640313 - - - -1.3271 - 2.634 0.347 - 193.3 1 2 0 -0.0024 14 0 0 0 1.29E+07 1.42E+07 - - - 2.5981 0.9999 221125_WJC_METTL3_EV_vs_WT_F06.16341.16341.2 3.07E-07 20-Nov R.NPEAALSPTFR[166.11].S "sp|Q86U44|MTA70_HUMAN,tr|B4E349|B4E349_HUMAN,tr|F5H6D8|F5H6D8_HUMAN,tr|B4DTN4|B4DTN4_HUMAN" 4 1211.6174 0.02 85091 16341 2 1211.617483 606.816 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 6 2721.4 - 1.10E+07 - - - 0.0627 - 2.422 0.532 - 669.8 1 2 0 0.0001 11 0 0 0 2.13E+07 9.93E+08 - - - 5.3634 1 221125_WJC_METTL3_EV_vs_WT_F06.16345.16345.4 0.000446 20/78 K.FEQIYLSK[136.11]PTHWER[166.11].D "sp|P30876|RPB2_HUMAN,tr|C9J2Y9|C9J2Y9_HUMAN" 2 1850.9434 1.18 85095 16345 4 1850.942551 463.7431 DNA-directed RNA polymerase II subunit RPB2 OS=Homo sapiens OX=9606 GN=POLR2B PE=1 SV=1 6.76 2721.8 - 1.02E+06 - - - -0.4798 - 3.642 0.493 - 377.3 1 2 0 -0.0009 14 0 0 0 2.22E+07 1.88E+07 - - - 3.9872 1 221125_WJC_METTL3_EV_vs_WT_F06.16354.16354.2 5.08E-06 20/26 R.RQVQSLTC[160.03]EVDALK.G "sp|P08670|VIME_HUMAN,tr|B0YJC5|B0YJC5_HUMAN,tr|B0YJC4|B0YJC4_HUMAN" 3 1645.8458 2.28 85102 16354 2 1645.844639 823.9302 Vimentin OS=Homo sapiens OX=9606 GN=VIM PE=1 SV=4 6.06 2722.9 - 2.15E+06 - - - -0.6781 - 3.741 0.593 - 1095.1 1 2 0 -0.0011 14 0 0 0 3.42E+07 1.50E+07 - - - 6.7314 1 221125_WJC_METTL3_EV_vs_WT_F06.16356.16356.3 8.46E-08 19/88 R.EGPGSEPDSQVDGGLSGASLGEK.K "sp|Q5JSZ5|PRC2B_HUMAN,tr|A0A804HKC3|A0A804HKC3_HUMAN,tr|A0A804HJR4|A0A804HJR4_HUMAN" 3 2171.9819 0.95 85104 16356 3 2171.978385 725.0012 Protein PRRC2B OS=Homo sapiens OX=9606 GN=PRRC2B PE=1 SV=2 3.83 2723.1 - 1.29E+06 - - - -1.5958 - 3.516 0.588 - 312.9 1 2 0 -0.0035 23 0 0 0 1.46E+07 1.54E+07 - - - 8.0443 0.9999 221125_WJC_METTL3_EV_vs_WT_F06.16357.16357.2 4.73E-05 17/26 R.R[166.11]QVQSLTC[160.03]EVDALK[136.11].G "sp|P08670|VIME_HUMAN,tr|B0YJC5|B0YJC5_HUMAN,tr|B0YJC4|B0YJC4_HUMAN" 3 1663.8682 2.28 85105 16357 2 1663.867863 832.9414 Vimentin OS=Homo sapiens OX=9606 GN=VIM PE=1 SV=4 6.06 2723.3 - 1.11E+06 - - - -0.2176 - 3.327 0.492 - 793 1 2 0 -0.0004 14 0 0 0 3.42E+07 1.50E+07 - - - 5.6913 0.9209 221125_WJC_METTL3_EV_vs_WT_F06.16360.16360.2 0.0231 Jul-32 K.DAATGTASIIVNNEGQN.L sp|Q9H477|RBSK_HUMAN 1 1673.7857 - 85108 16360 2 1673.785579 837.9001 Ribokinase OS=Homo sapiens OX=9606 GN=RBKS PE=1 SV=1 3.67 2723.6 - 739951 - - - -0.0466 - 1.363 0.324 - 50.1 2 1 0 -0.0001 17 0 0 0 - - - - - 2.061 1 221125_WJC_METTL3_EV_vs_WT_F06.16364.16364.3 3.69E-06 18/52 R.RQVQSLTC[160.03]EVDALK.G "sp|P08670|VIME_HUMAN,tr|B0YJC5|B0YJC5_HUMAN,tr|B0YJC4|B0YJC4_HUMAN" 3 1645.8458 1.97 85110 16364 3 1645.845099 549.6225 Vimentin OS=Homo sapiens OX=9606 GN=VIM PE=1 SV=4 6.06 2724.2 - 1.46E+07 - - - -0.3986 - 3.383 0.399 - 463.7 1 2 0 -0.0007 14 0 0 0 2.05E+08 1.04E+08 - - - 6.2272 0.9995 221125_WJC_METTL3_EV_vs_WT_F06.16370.16370.3 0.000278 15/44 K.IRDYAFVHFTSR.E "sp|A0AV96|RBM47_HUMAN,tr|B7Z8Z7|B7Z8Z7_HUMAN,tr|D6R9D6|D6R9D6_HUMAN" 3 1510.7681 0.49 85116 16370 3 1510.766151 504.5966 RNA-binding protein 47 OS=Homo sapiens OX=9606 GN=RBM47 PE=1 SV=2 8.75 2724.7 - 794011 - - - -1.2881 - 2.496 0.37 - 344.3 1 2 1 -0.0019 12 0 0 0 1.63E+07 3.35E+07 - - - 5.2 0.9998 221125_WJC_METTL3_EV_vs_WT_F06.16374.16374.3 0.00012 Oct-48 R.EQDLPLAEAVR[166.11]PK[136.11].T sp|Q96A49|SYAP1_HUMAN 1 1482.8161 4.78 85120 16374 3 1482.814435 495.2793 Synapse-associated protein 1 OS=Homo sapiens OX=9606 GN=SYAP1 PE=1 SV=1 4.68 2725.3 - 451862 - - - -1.1316 - 1.682 0.439 - 90.8 1 2 0 -0.0017 13 0 0 0 8.47E+07 1.77E+07 - - - 4.8438 0.9999 221125_WJC_METTL3_EV_vs_WT_F06.16377.16377.3 0.000202 Dec-56 K.QNK[136.11]PTGFALGSIEGR[166.11].V "sp|P78406|RAE1L_HUMAN,tr|E9PQ57|E9PQ57_HUMAN" 2 1591.8437 1.72 85121 16377 3 1591.844343 531.6219 mRNA export factor OS=Homo sapiens OX=9606 GN=RAE1 PE=1 SV=1 8.75 2725.7 - 7.39E+06 - - - 0.3882 - 2.367 0.434 - 166 1 2 0 0.0006 15 0 0 0 3.55E+08 2.06E+08 - - - 5.6268 1 221125_WJC_METTL3_EV_vs_WT_F06.16378.16378.3 2.08E-08 17/56 K.KVPQVSTPTLVEVSR.N "sp|P02768|ALBU_HUMAN,tr|A0A087WWT3|A0A087WWT3_HUMAN,tr|B7WNR0|B7WNR0_HUMAN,tr|H0YA55|H0YA55_HUMAN,tr|A0A0C4DGB6|A0A0C4DGB6_HUMAN,tr|D6RHD5|D6RHD5_HUMAN,tr|C9JKR2|C9JKR2_HUMAN" 7 1638.9305 999 85122 16378 3 1638.930354 547.3174 Albumin OS=Homo sapiens OX=9606 GN=ALB PE=1 SV=2 8.75 2725.7 - 7.11E+06 - - - -0.0714 - 3.242 0.587 - 487.6 1 2 0 -0.0001 15 0 0 0 1.45E+08 0.00E+00 - - - 8.1535 1 221125_WJC_METTL3_EV_vs_WT_F06.16380.16380.3 8.95E-11 21/56 K.STHSELLEDYYQSGR[166.11].M "sp|P28288|ABCD3_HUMAN,tr|A0A3B3ITW3|A0A3B3ITW3_HUMAN" 2 1793.8096 1.21 85124 16380 3 1793.810787 598.9438 ATP-binding cassette sub-family D member 3 OS=Homo sapiens OX=9606 GN=ABCD3 PE=1 SV=1 4.65 2725.9 - 1.69E+06 - - - 0.6745 - 3.44 0.688 - 539.6 1 2 0 0.0012 15 0 0 0 3.65E+07 3.03E+07 - - - 9.434 0.9993 221125_WJC_METTL3_EV_vs_WT_F06.16381.16381.3 3.05E-07 17/64 K.AHAAVWNAQEAQADFAK[136.11].V "sp|O00170|AIP_HUMAN,tr|A0A804HKK3|A0A804HKK3_HUMAN,tr|A0A804HKL7|A0A804HKL7_HUMAN,tr|A0A804HJ46|A0A804HJ46_HUMAN,tr|E9PMH2|E9PMH2_HUMAN,tr|A0A804HKH9|A0A804HKH9_HUMAN" 6 1834.8842 1.99 85125 16381 3 1835.884084 612.6353 AH receptor-interacting protein OS=Homo sapiens OX=9606 GN=AIP PE=1 SV=2 5.32 2725.9 - 1.60E+06 - - - 544.9325 - 3.285 0.563 - 473 1 2 0 0.9999 17 0 0 0 4.67E+07 2.35E+07 - - - 7.5446 1 221125_WJC_METTL3_EV_vs_WT_F06.16382.16382.3 5.38E-05 14/52 K.DAHNALLDIQSSGR[166.11].A "sp|Q99613|EIF3C_HUMAN,sp|B5ME19|EIFCL_HUMAN" 2 1505.7462 1.05 85126 16382 3 1505.746742 502.9227 Eukaryotic translation initiation factor 3 subunit C OS=Homo sapiens OX=9606 GN=EIF3C PE=1 SV=1 5.21 2726 - 1.32E+06 - - - 0.3673 - 2.857 0.476 - 340 1 2 0 0.0006 14 0 0 0 1.46E+08 1.39E+08 - - - 6.6366 1 221125_WJC_METTL3_EV_vs_WT_F06.16384.16384.3 9.04E-06 16/52 K.FEQIYLSK[136.11]PTHWER[166.11].D "sp|P30876|RPB2_HUMAN,tr|C9J2Y9|C9J2Y9_HUMAN" 2 1850.9434 0.38 85128 16384 3 1850.944463 617.9884 DNA-directed RNA polymerase II subunit RPB2 OS=Homo sapiens OX=9606 GN=POLR2B PE=1 SV=1 6.76 2726.3 - 992385 - - - 0.5532 - 2.811 0.454 - 122.5 1 2 0 0.001 14 0 0 0 1.05E+07 2.79E+07 - - - 6.348 0.9998 221125_WJC_METTL3_EV_vs_WT_F06.16388.16388.2 2.67E-08 14/32 K.AHAAVWNAQEAQADFAK.V "sp|O00170|AIP_HUMAN,tr|A0A804HKK3|A0A804HKK3_HUMAN,tr|A0A804HKL7|A0A804HKL7_HUMAN,tr|A0A804HJ46|A0A804HJ46_HUMAN,tr|E9PMH2|E9PMH2_HUMAN,tr|A0A804HKH9|A0A804HKH9_HUMAN" 6 1826.87 1.67 85132 16388 2 1826.866934 914.4423 AH receptor-interacting protein OS=Homo sapiens OX=9606 GN=AIP PE=1 SV=2 5.32 2726.8 - 284457 - - - -1.6761 - 2.424 0.52 - 480.5 1 2 0 -0.0031 17 0 0 0 1.77E+06 1.06E+06 - - - 5.0576 0.968 221125_WJC_METTL3_EV_vs_WT_F06.16390.16390.3 0.0474 Aug-56 R.ADTQTYQPYNKDWIK.E sp|P84090|ERH_HUMAN 1 1869.8897 0.35 85133 16390 3 1869.887074 624.3039 Enhancer of rudimentary homolog OS=Homo sapiens OX=9606 GN=ERH PE=1 SV=1 6 2727 - 2.27E+06 - - - -1.4193 - 1.697 0.212 - 74.4 2 2 1 -0.0027 15 0 0 0 3.76E+07 1.07E+08 - - - 2.1435 0.9999 221125_WJC_METTL3_EV_vs_WT_F06.16392.16392.2 4.52E-05 14/32 K.ANELPQPPVPEPANAGK.R "sp|P78347|GTF2I_HUMAN,tr|A0A494C1K3|A0A494C1K3_HUMAN" 2 1727.8842 2.33 85134 16392 2 1727.885046 864.9494 General transcription factor II-I OS=Homo sapiens OX=9606 GN=GTF2I PE=1 SV=2 4.53 2727.2 - 3.30E+06 - - - 0.4613 - 2.291 0.485 - 404.4 1 2 0 0.0008 17 0 0 0 3.70E+09 1.59E+09 - - - 4.6611 0.9999 221125_WJC_METTL3_EV_vs_WT_F06.16394.16394.3 0.000359 13/56 K.QNKPTGFALGSIEGR.V "sp|P78406|RAE1L_HUMAN,tr|E9PQ57|E9PQ57_HUMAN" 2 1573.8213 1.71 85136 16394 3 1573.822731 525.6144 mRNA export factor OS=Homo sapiens OX=9606 GN=RAE1 PE=1 SV=1 8.75 2727.3 - 1.72E+07 - - - 0.9378 - 2.504 0.378 - 178.1 1 2 0 0.0015 15 0 0 0 3.55E+08 2.07E+08 - - - 5.149 0.9999 221125_WJC_METTL3_EV_vs_WT_F06.16397.16397.3 5.71E-05 Dec-40 R.NPEAALSPTFR[166.11].S "sp|Q86U44|MTA70_HUMAN,tr|B4E349|B4E349_HUMAN,tr|F5H6D8|F5H6D8_HUMAN,tr|B4DTN4|B4DTN4_HUMAN" 4 1211.6174 0.01 85139 16397 3 1211.617278 404.8797 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 6 2727.5 - 3.32E+06 - - - -0.1065 - 2.347 0.417 - 312.3 1 2 0 -0.0001 11 0 0 0 5.23E+05 5.14E+07 - - - 5.6127 0.9999 221125_WJC_METTL3_EV_vs_WT_F06.16398.16398.4 6.88E-06 13/108 R.GLLQDDAHPTLVTYADHSK[136.11].L "sp|Q86U44|MTA70_HUMAN,tr|F5H6D8|F5H6D8_HUMAN,tr|H0YFV6|H0YFV6_HUMAN,tr|B4DTN4|B4DTN4_HUMAN" 4 2088.0367 0.02 85140 16398 4 2088.035076 523.0165 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 5.13 2727.5 - 2.40E+06 - - - -0.7936 - 2.655 0.457 - 161 1 2 0 -0.0017 19 0 0 0 9.14E+05 3.82E+07 - - - 3.5336 1 221125_WJC_METTL3_EV_vs_WT_F06.16399.16399.3 2.28E-06 Dec-76 R.FSSC[160.03]GGGGGSFGAGGGFGSR.S sp|P04264|K2C1_HUMAN 1 1764.7274 -1 85141 16399 3 1764.728269 589.2498 "Keratin, type II cytoskeletal 1 OS=Homo sapiens OX=9606 GN=KRT1 PE=1 SV=6" 8.25 2727.6 - 1.46E+06 - - - 0.4749 - 2.567 0.63 - 123.3 1 2 0 0.0008 20 0 0 0 0.00E+00 0.00E+00 - - - 7.8507 0.9988 221125_WJC_METTL3_EV_vs_WT_F06.16400.16400.3 1.90E-10 20/72 K.PSTASAVPELATDPELEK[136.11]K[136.11].L "sp|Q86U44|MTA70_HUMAN,tr|B4E349|B4E349_HUMAN,tr|F5H6D8|F5H6D8_HUMAN,tr|H0YFV6|H0YFV6_HUMAN,tr|B4DTN4|B4DTN4_HUMAN" 5 1998.0492 0 85142 16400 3 1998.051163 667.0237 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 4.41 2727.7 - 1.36E+06 - - - 0.9815 - 3.506 0.596 - 413.5 1 1 0 0.002 19 0 0 0 1.61E+06 6.47E+09 - - - 8.2663 0.9999 221125_WJC_METTL3_EV_vs_WT_F06.16401.16401.2 2.24E-06 13/28 K.QNKPTGFALGSIEGR.V "sp|P78406|RAE1L_HUMAN,tr|E9PQ57|E9PQ57_HUMAN" 2 1573.8213 2.84 85143 16401 2 1573.82055 787.9179 mRNA export factor OS=Homo sapiens OX=9606 GN=RAE1 PE=1 SV=1 8.75 2727.8 - 1.32E+06 - - - -0.448 - 2.325 0.526 - 329.2 1 2 0 -0.0007 15 0 0 0 2.35E+07 8.29E+06 - - - 5.0001 0.9999 221125_WJC_METTL3_EV_vs_WT_F06.16402.16402.2 1.30E-06 20-Dec R.NPEAALSPTFR.S "sp|Q86U44|MTA70_HUMAN,tr|B4E349|B4E349_HUMAN,tr|F5H6D8|F5H6D8_HUMAN,tr|B4DTN4|B4DTN4_HUMAN" 4 1201.6091 0.02 85144 16402 2 1201.609642 601.8118 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 6 2727.9 - 1.15E+06 - - - 0.4203 - 2.596 0.506 - 624.6 1 2 0 0.0005 11 0 0 0 2.13E+07 9.93E+08 - - - 5.3589 1 221125_WJC_METTL3_EV_vs_WT_F06.16404.16404.3 1.81E-16 24/68 F.FHQDQSPVGGLTAEDIEK.A sp|Q8NI60|COQ8A_HUMAN 1 1969.9381 0.61 85146 16404 3 1969.93681 657.6533 "Atypical kinase COQ8A, mitochondrial OS=Homo sapiens OX=9606 GN=COQ8A PE=1 SV=1" 4.31 2728.1 - 997347 - - - -0.6726 - 4.423 0.705 - 909.1 1 1 0 -0.0013 18 0 0 0 2.17E+07 3.54E+07 - - - 10.102 1 221125_WJC_METTL3_EV_vs_WT_F06.16407.16407.2 1.98E-13 17/26 K.DAHNALLDIQSSGR[166.11].A "sp|Q99613|EIF3C_HUMAN,sp|B5ME19|EIFCL_HUMAN" 2 1505.7462 1 85149 16407 2 1505.748753 753.8804 Eukaryotic translation initiation factor 3 subunit C OS=Homo sapiens OX=9606 GN=EIF3C PE=1 SV=1 5.21 2728.5 - 398441 - - - 1.7028 - 3.019 0.706 - 1081.4 1 2 0 0.0026 14 0 0 0 1.98E+07 1.97E+07 - - - 7.0275 0.9983 221125_WJC_METTL3_EV_vs_WT_F06.16412.16412.3 1.06E-10 20/68 F.FHQDQSPVGGLTAEDIEK[136.11].A sp|Q8NI60|COQ8A_HUMAN 1 1977.9523 0.98 85152 16412 3 1977.950596 660.3247 "Atypical kinase COQ8A, mitochondrial OS=Homo sapiens OX=9606 GN=COQ8A PE=1 SV=1" 4.31 2729.1 - 1.05E+06 - - - -0.8792 - 3.608 0.504 - 616.1 1 1 0 -0.0017 18 0 0 0 1.64E+07 1.68E+07 - - - 7.3538 0.9999 221125_WJC_METTL3_EV_vs_WT_F06.16420.16420.3 5.52E-06 Dec-52 K.RDPTAEQFQEELEK.F sp|P31944|CASPE_HUMAN 1 1718.8111 3.71 85158 16420 3 1718.816046 573.9443 Caspase-14 OS=Homo sapiens OX=9606 GN=CASP14 PE=1 SV=2 4.25 2730 - 743800 - - - 2.852 - 2.588 0.487 - 189.6 1 2 0 0.0049 14 0 0 0 1.35E+08 3.64E+07 - - - 6.4952 0.9994 221125_WJC_METTL3_EV_vs_WT_F06.16424.16424.3 2.19E-05 Nov-56 K.EVMDSLK[136.11]QETQGLQK[136.11].E "sp|Q9NTJ3|SMC4_HUMAN,tr|E9PD53|E9PD53_HUMAN" 2 1748.895 0.39 85160 16424 3 1748.895479 583.9723 Structural maintenance of chromosomes protein 4 OS=Homo sapiens OX=9606 GN=SMC4 PE=1 SV=2 4.68 2730.6 - 880838 - - - 0.3025 - 2.319 0.375 - 98.1 1 2 1 0.0005 15 0 0 0 6.98E+06 1.81E+07 - - - 4.9156 0.9999 221125_WJC_METTL3_EV_vs_WT_F06.16425.16425.3 4.10E-07 18/44 R.TKEIEAIHAILR.S sp|Q15643|TRIPB_HUMAN 1 1392.8089 1.2 85161 16425 3 1392.809365 465.2769 Thyroid receptor-interacting protein 11 OS=Homo sapiens OX=9606 GN=TRIP11 PE=1 SV=3 6.42 2730.7 - 924970 - - - 0.3346 - 2.921 0.568 - 472.3 1 2 1 0.0005 12 0 0 0 2.43E+08 2.03E+08 - - - 7.8437 0.8889 221125_WJC_METTL3_EV_vs_WT_F06.16426.16426.3 0.00257 Nov-64 K.LESENDLQEIHTIQEC[160.03]K[136.11].E "sp|Q03112|MECOM_HUMAN,tr|H9KVD4|H9KVD4_HUMAN,tr|E7ERX0|E7ERX0_HUMAN,tr|E7EUL6|E7EUL6_HUMAN,tr|A0A0C3SFZ7|A0A0C3SFZ7_HUMAN,tr|E7EPY2|E7EPY2_HUMAN" 6 2092.9826 0.38 85162 16426 3 2093.9835 698.6682 Histone-lysine N-methyltransferase MECOM OS=Homo sapiens OX=9606 GN=MECOM PE=1 SV=3 4.25 2730.8 - 1.54E+06 - - - 478.1936 - 2.101 0.202 - 82.7 1 2 0 1.0009 17 0 0 0 8.57E+06 2.23E+07 - - - 2.3904 0.9437 221125_WJC_METTL3_EV_vs_WT_F06.16430.16430.4 0.289 Sep-90 K.VILHLK[136.11]EDQTEYLEER[166.11].R "sp|P08238|HS90B_HUMAN,sp|Q58FF6|H90B4_HUMAN,sp|Q58FF7|H90B3_HUMAN,sp|P07900|HS90A_HUMAN,tr|G3V2J8|G3V2J8_HUMAN" 5 2032.0596 1.13 85166 16430 4 2032.061468 509.0222 Heat shock protein HSP 90-beta OS=Homo sapiens OX=9606 GN=HSP90AB1 PE=1 SV=4 4.57 2731.3 - 352209 - - - 0.9237 - 1.834 0.183 - 77.7 1 2 1 0.0019 16 0 0 0 3.21E+07 2.85E+07 - - - 1.032 0.9999 221125_WJC_METTL3_EV_vs_WT_F06.16438.16438.3 0.00107 Dec-40 R.AVFPSIVGRPR.Q "sp|Q6S8J3|POTEE_HUMAN,sp|P63261|ACTG_HUMAN,sp|P68133|ACTS_HUMAN,sp|P62736|ACTA_HUMAN,sp|Q9BYX7|ACTBM_HUMAN,sp|P68032|ACTC_HUMAN,sp|P60709|ACTB_HUMAN,sp|P63267|ACTH_HUMAN,sp|A5A3E0|POTEF_HUMAN,sp|P0CG38|POTEI_HUMAN,tr|A0A804GS07|A0A804GS07_HUMAN,tr|I3L3I0|I3L3I0_HUMAN,tr|G5E9R0|G5E9R0_HUMAN,tr|E7EVS6|E7EVS6_HUMAN,tr|B8ZZJ2|B8ZZJ2_HUMAN,tr|J3KT65|J3KT65_HUMAN,tr|I3L3R2|I3L3R2_HUMAN,tr|K7EM38|K7EM38_HUMAN,tr|F6QUT6|F6QUT6_HUMAN,tr|C9JTX5|C9JTX5_HUMAN,tr|A0A6Q8PH58|A0A6Q8PH58_HUMAN,tr|F6UVQ4|F6UVQ4_HUMAN,tr|F8WB63|F8WB63_HUMAN,tr|I3L1U9|I3L1U9_HUMAN,tr|A0A2R8Y793|A0A2R8Y793_HUMAN,tr|I3L4N8|I3L4N8_HUMAN,tr|C9JUM1|C9JUM1_HUMAN,tr|F8WCH0|F8WCH0_HUMAN,tr|C9JZR7|C9JZR7_HUMAN,tr|C9JFL5|C9JFL5_HUMAN,tr|A0A2R8YGF8|A0A2R8YGF8_HUMAN,tr|A6NL76|A6NL76_HUMAN" 32 1197.6982 1.16 85172 16438 3 1197.697951 400.24 POTE ankyrin domain family member E OS=Homo sapiens OX=9606 GN=POTEE PE=2 SV=3 12 2732.1 - 567501 - - - -0.2296 - 2.437 0.431 - 213.1 1 2 0 -0.0003 11 0 0 0 1.62E+07 1.39E+07 - - - 5.8757 0.9999 221125_WJC_METTL3_EV_vs_WT_F06.16444.16444.3 4.45E-09 18/44 R.TK[136.11]EIEAIHAILR[166.11].S sp|Q15643|TRIPB_HUMAN 1 1410.8314 1.2 85176 16444 3 1410.832769 471.2844 Thyroid receptor-interacting protein 11 OS=Homo sapiens OX=9606 GN=TRIP11 PE=1 SV=3 6.42 2732.9 - 3.60E+06 - - - 0.9923 - 2.95 0.601 - 468.3 1 2 1 0.0014 12 0 0 0 2.43E+08 2.03E+08 - - - 8.2388 0.989 221125_WJC_METTL3_EV_vs_WT_F06.16445.16445.3 0.00311 16/72 K.PSTASAVPELATDPELEKK[136.11].L "sp|Q86U44|MTA70_HUMAN,tr|B4E349|B4E349_HUMAN,tr|F5H6D8|F5H6D8_HUMAN,tr|H0YFV6|H0YFV6_HUMAN,tr|B4DTN4|B4DTN4_HUMAN" 5 1990.035 - 85177 16445 3 1990.040003 664.3523 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 4.41 2733 - 628501 - - - 2.513 - 3.042 0.442 - 221.1 1 1 0 0.005 19 0 0 0 - - - - - 6.1997 1 221125_WJC_METTL3_EV_vs_WT_F06.16451.16451.3 8.88E-07 18/60 K.R[166.11]NFILDQTNVSAAAQR[166.11].R "sp|Q00839|HNRPU_HUMAN,tr|A0A1W2PQL0|A0A1W2PQL0_HUMAN,tr|A0A1W2PPL4|A0A1W2PPL4_HUMAN,tr|A0A1W2PQ74|A0A1W2PQ74_HUMAN,tr|Q5RI18|Q5RI18_HUMAN,tr|A0A1W2PP35|A0A1W2PP35_HUMAN,tr|A0A1W2PPS1|A0A1W2PPS1_HUMAN,tr|A0A1W2PRZ7|A0A1W2PRZ7_HUMAN,tr|A0A1W2PPH7|A0A1W2PPH7_HUMAN,tr|A0A1W2PQD4|A0A1W2PQD4_HUMAN,tr|A0A1W2PP34|A0A1W2PP34_HUMAN,tr|A0A1X7SBS1|A0A1X7SBS1_HUMAN" 12 1822.9553 1.05 85181 16451 3 1822.954811 608.659 Heterogeneous nuclear ribonucleoprotein U OS=Homo sapiens OX=9606 GN=HNRNPU PE=1 SV=6 9.6 2733.8 - 3.12E+06 - - - -0.2595 - 3.57 0.568 - 450.7 1 2 0 -0.0005 16 0 0 0 1.93E+08 1.84E+08 - - - 8.1377 1 221125_WJC_METTL3_EV_vs_WT_F06.16453.16453.3 1.03E-05 20/56 R.YGISSMIQSQEK[136.11]PDR[166.11].V "sp|P14868|SYDC_HUMAN,tr|H7C278|H7C278_HUMAN" 2 1755.8581 0.86 85183 16453 3 1755.855464 586.2933 "Aspartate--tRNA ligase, cytoplasmic OS=Homo sapiens OX=9606 GN=DARS1 PE=1 SV=2" 6.07 2734 - 939260 - - - -1.4751 - 3.784 0.597 - 436.9 1 2 0 -0.0026 15 0 0 0 8.19E+07 9.54E+07 - - - 8.6677 1 221125_WJC_METTL3_EV_vs_WT_F06.16455.16455.3 3.38E-11 25/112 R.EPGGYAAAGSGGAGGVSGGGSSLAAMGGR.E sp|Q92908|GATA6_HUMAN 1 2365.0717 1.59 85185 16455 3 2365.081446 789.3645 Transcription factor GATA-6 OS=Homo sapiens OX=9606 GN=GATA6 PE=1 SV=2 6.1 2734.2 - 451043 - - - 4.1271 - 4.08 0.667 - 438.1 1 2 0 0.0098 29 0 0 0 6.58E+06 4.14E+06 - - - 9.2086 0.9986 221125_WJC_METTL3_EV_vs_WT_F06.16461.16461.3 0.000308 16/72 R.QAPAPTVIR[166.11]DPPSITPAVK[136.11].S sp|Q13112|CAF1B_HUMAN 1 1975.1221 0.61 85189 16461 3 1975.123424 659.3813 Chromatin assembly factor 1 subunit B OS=Homo sapiens OX=9606 GN=CHAF1B PE=1 SV=1 8.75 2735 - 906188 - - - 0.6541 - 2.204 0.336 - 277.4 1 2 1 0.0013 19 0 0 0 1.14E+07 1.88E+07 - - - 4.2273 0.9999 221125_WJC_METTL3_EV_vs_WT_F06.16462.16462.3 0.0205 15/52 K.AQIHDLVLVGGSTR[166.11].L "sp|P0DMV8|HS71A_HUMAN,sp|P0DMV9|HS71B_HUMAN,tr|V9GZ37|V9GZ37_HUMAN,tr|A0A0G2JIW1|A0A0G2JIW1_HUMAN" 4 1474.8131 0.18 85190 16462 3 1474.815141 492.6117 Heat shock 70 kDa protein 1A OS=Homo sapiens OX=9606 GN=HSPA1A PE=1 SV=1 6.79 2735.1 - 1.03E+06 - - - 1.3527 - 2.884 0.377 - 250.2 1 2 0 0.002 14 0 0 0 6.03E+07 3.43E+08 - - - 5.5574 0.9994 221125_WJC_METTL3_EV_vs_WT_F06.16465.16465.2 0.00107 30-Jul K.R[166.11]NFILDQTNVSAAAQR[166.11].R "sp|Q00839|HNRPU_HUMAN,tr|A0A1W2PQL0|A0A1W2PQL0_HUMAN,tr|A0A1W2PPL4|A0A1W2PPL4_HUMAN,tr|A0A1W2PQ74|A0A1W2PQ74_HUMAN,tr|Q5RI18|Q5RI18_HUMAN,tr|A0A1W2PP35|A0A1W2PP35_HUMAN,tr|A0A1W2PPS1|A0A1W2PPS1_HUMAN,tr|A0A1W2PRZ7|A0A1W2PRZ7_HUMAN,tr|A0A1W2PPH7|A0A1W2PPH7_HUMAN,tr|A0A1W2PQD4|A0A1W2PQD4_HUMAN,tr|A0A1W2PP34|A0A1W2PP34_HUMAN,tr|A0A1X7SBS1|A0A1X7SBS1_HUMAN" 12 1822.9553 1.91 85193 16465 2 1822.957504 912.4849 Heterogeneous nuclear ribonucleoprotein U OS=Homo sapiens OX=9606 GN=HNRNPU PE=1 SV=6 9.6 2735.5 - 175396 - - - 1.2178 - 1.751 0.375 - 40.4 1 2 0 0.0022 16 0 0 0 3.22E+07 1.68E+07 - - - 3.1873 0.9999 221125_WJC_METTL3_EV_vs_WT_F06.16469.16469.3 1.30E-08 19/68 K.GPTEQLVSPEPEVHDIER[166.11].S sp|P35813|PPM1A_HUMAN 1 2040.9992 0.79 85195 16469 3 2040.991739 681.3403 Protein phosphatase 1A OS=Homo sapiens OX=9606 GN=PPM1A PE=1 SV=1 4.25 2736 - 1.11E+06 - - - -3.6404 - 3.382 0.57 - 364.7 1 2 0 -0.0074 18 0 0 0 5.68E+07 7.21E+07 - - - 7.927 1 221125_WJC_METTL3_EV_vs_WT_F06.16470.16470.3 8.78E-07 17/56 R.YGISSMIQSQEKPDR.V "sp|P14868|SYDC_HUMAN,tr|H7C278|H7C278_HUMAN" 2 1737.8356 0.74 85196 16470 3 1737.837142 580.2858 "Aspartate--tRNA ligase, cytoplasmic OS=Homo sapiens OX=9606 GN=DARS1 PE=1 SV=2" 6.07 2736 - 2.15E+06 - - - 0.8965 - 2.661 0.479 - 345.2 1 2 0 0.0016 15 0 0 0 6.81E+07 9.24E+07 - - - 6.4337 0.9734 221125_WJC_METTL3_EV_vs_WT_F06.16471.16471.4 0.00761 15/90 K.VILHLKEDQTEYLEER.R "sp|P08238|HS90B_HUMAN,sp|Q58FF6|H90B4_HUMAN,sp|Q58FF7|H90B3_HUMAN,sp|P07900|HS90A_HUMAN,tr|G3V2J8|G3V2J8_HUMAN" 5 2014.0371 1.93 85197 16471 4 2014.03158 504.5166 Heat shock protein HSP 90-beta OS=Homo sapiens OX=9606 GN=HSP90AB1 PE=1 SV=4 4.57 2736.2 - 1.49E+06 - - - -2.7512 - 2.413 0.243 - 171.9 1 2 1 -0.0055 16 0 0 0 9.19E+07 4.76E+07 - - - 1.6498 1 221125_WJC_METTL3_EV_vs_WT_F06.16473.16473.2 8.27E-12 22/36 R.GLLQDDAHPTLVTYADHSK[136.11].L "sp|Q86U44|MTA70_HUMAN,tr|F5H6D8|F5H6D8_HUMAN,tr|H0YFV6|H0YFV6_HUMAN,tr|B4DTN4|B4DTN4_HUMAN" 4 2088.0367 0.01 85199 16473 2 2088.037737 1045.0256 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 5.13 2736.4 - 595507 - - - 0.4808 - 3.811 0.686 - 1133.3 1 2 0 0.001 19 0 0 0 1.61E+09 1.21E+11 - - - 7.3967 0.9999 221125_WJC_METTL3_EV_vs_WT_F06.16474.16474.3 0.000273 Nov-40 R.AVFPSIVGR[166.11]PR[166.11].Q "sp|Q6S8J3|POTEE_HUMAN,sp|P63261|ACTG_HUMAN,sp|P68133|ACTS_HUMAN,sp|P62736|ACTA_HUMAN,sp|Q9BYX7|ACTBM_HUMAN,sp|P68032|ACTC_HUMAN,sp|P60709|ACTB_HUMAN,sp|P63267|ACTH_HUMAN,sp|A5A3E0|POTEF_HUMAN,sp|P0CG38|POTEI_HUMAN,tr|A0A804GS07|A0A804GS07_HUMAN,tr|I3L3I0|I3L3I0_HUMAN,tr|G5E9R0|G5E9R0_HUMAN,tr|E7EVS6|E7EVS6_HUMAN,tr|B8ZZJ2|B8ZZJ2_HUMAN,tr|J3KT65|J3KT65_HUMAN,tr|I3L3R2|I3L3R2_HUMAN,tr|K7EM38|K7EM38_HUMAN,tr|F6QUT6|F6QUT6_HUMAN,tr|C9JTX5|C9JTX5_HUMAN,tr|A0A6Q8PH58|A0A6Q8PH58_HUMAN,tr|F6UVQ4|F6UVQ4_HUMAN,tr|F8WB63|F8WB63_HUMAN,tr|I3L1U9|I3L1U9_HUMAN,tr|A0A2R8Y793|A0A2R8Y793_HUMAN,tr|I3L4N8|I3L4N8_HUMAN,tr|C9JUM1|C9JUM1_HUMAN,tr|F8WCH0|F8WCH0_HUMAN,tr|C9JZR7|C9JZR7_HUMAN,tr|C9JFL5|C9JFL5_HUMAN,tr|A0A2R8YGF8|A0A2R8YGF8_HUMAN,tr|A6NL76|A6NL76_HUMAN" 32 1217.7148 1.15 85200 16474 3 1217.715322 406.9122 POTE ankyrin domain family member E OS=Homo sapiens OX=9606 GN=POTEE PE=2 SV=3 12 2736.6 - 474054 - - - 0.4566 - 2.024 0.427 - 168.7 1 2 0 0.0006 11 0 0 0 1.62E+07 1.41E+07 - - - 5.3035 0.9988 221125_WJC_METTL3_EV_vs_WT_F06.16475.16475.3 0.0316 Jun-40 R.LK[136.11]VGLQVVAVK[136.11].A "sp|P10809|CH60_HUMAN,tr|A0A7I2V2X6|A0A7I2V2X6_HUMAN,tr|A0A7I2YQK6|A0A7I2YQK6_HUMAN,tr|A0A7I2V599|A0A7I2V599_HUMAN,tr|A0A7I2V5M1|A0A7I2V5M1_HUMAN" 5 1168.7878 0.69 85201 16475 3 1168.787236 390.6032 "60 kDa heat shock protein, mitochondrial OS=Homo sapiens OX=9606 GN=HSPD1 PE=1 SV=2" 10 2736.7 - 451836 - - - -0.5082 - 1.667 0.388 - 32.8 1 2 1 -0.0006 11 0 0 0 3.06E+06 4.47E+06 - - - 4.3174 1 221125_WJC_METTL3_EV_vs_WT_F06.16479.16479.3 7.33E-09 21/64 K.ANELPQPPVPEPANAGK.R "sp|P78347|GTF2I_HUMAN,tr|A0A494C1K3|A0A494C1K3_HUMAN" 2 1727.8842 3.01 85204 16479 3 1727.887008 576.9687 General transcription factor II-I OS=Homo sapiens OX=9606 GN=GTF2I PE=1 SV=2 4.53 2737.2 - 4.78E+06 - - - 1.5968 - 3.873 0.568 - 570.9 1 2 0 0.0028 17 0 0 0 1.21E+08 4.04E+07 - - - 8.2926 0.9999 221125_WJC_METTL3_EV_vs_WT_F06.16486.16486.4 1.26E-09 22/96 R.LTEADYLSSHLTEGPHR[166.11].V "sp|Q9BRJ7|TIRR_HUMAN,tr|W4VSQ8|W4VSQ8_HUMAN,tr|K7EIN2|K7EIN2_HUMAN,tr|K7ENA3|K7ENA3_HUMAN" 4 1934.9362 8.31 85208 16486 4 1934.930099 484.7413 Tudor-interacting repair regulator protein OS=Homo sapiens OX=9606 GN=NUDT16L1 PE=1 SV=1 5.27 2737.9 - 957299 - - - -3.1402 - 3.465 0.585 - 347.2 1 2 0 -0.0061 17 0 0 0 1.75E+08 2.11E+07 - - - 4.7476 0.982 221125_WJC_METTL3_EV_vs_WT_F06.16488.16488.4 0.00205 14/96 L.LQDDAHPTLVTYADHSK[136.11].L "sp|Q86U44|MTA70_HUMAN,tr|F5H6D8|F5H6D8_HUMAN,tr|H0YFV6|H0YFV6_HUMAN,tr|B4DTN4|B4DTN4_HUMAN" 4 1917.9312 0.01 85210 16488 4 1917.929403 480.4901 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 5.13 2738.1 - 6.55E+06 - - - -0.9401 - 2.344 0.394 - 128.7 1 1 0 -0.0018 17 0 0 0 2.62E+07 3.35E+09 - - - 2.9506 1 221125_WJC_METTL3_EV_vs_WT_F06.16493.16493.2 1.65E-11 20/28 Q.DDAHPTLVTYADHSK[136.11].L "sp|Q86U44|MTA70_HUMAN,tr|F5H6D8|F5H6D8_HUMAN,tr|H0YFV6|H0YFV6_HUMAN,tr|B4DTN4|B4DTN4_HUMAN" 4 1676.7886 0.01 85213 16493 2 1676.783635 839.4016 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 5.13 2738.8 - 1.93E+06 - - - -2.9395 - 3.259 0.698 - 1082 1 1 0 -0.0049 15 0 0 0 8.59E+06 1.07E+09 - - - 7.0995 0.9977 221125_WJC_METTL3_EV_vs_WT_F06.16496.16496.3 7.86E-07 20/56 Q.DDAHPTLVTYADHSK[136.11].L "sp|Q86U44|MTA70_HUMAN,tr|F5H6D8|F5H6D8_HUMAN,tr|H0YFV6|H0YFV6_HUMAN,tr|B4DTN4|B4DTN4_HUMAN" 4 1676.7886 0.01 85216 16496 3 1676.784906 559.9368 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 5.13 2738.9 - 4.98E+06 - - - -2.1816 - 3.177 0.59 - 563 1 1 0 -0.0037 15 0 0 0 1.79E+07 2.17E+09 - - - 8.1332 0.9999 221125_WJC_METTL3_EV_vs_WT_F06.16498.16498.3 1.07E-05 14/52 K.DAHNALLDIQSSGR.A "sp|Q99613|EIF3C_HUMAN,sp|B5ME19|EIFCL_HUMAN" 2 1495.7379 1.05 85217 16498 3 1495.736025 499.5866 Eukaryotic translation initiation factor 3 subunit C OS=Homo sapiens OX=9606 GN=EIF3C PE=1 SV=1 5.21 2739.2 - 1.49E+06 - - - -1.2663 - 2.419 0.44 - 385.3 1 2 0 -0.0019 14 0 0 0 1.46E+08 1.39E+08 - - - 5.7926 1 221125_WJC_METTL3_EV_vs_WT_F06.16507.16507.2 1.69E-14 22/30 L.QDDAHPTLVTYADHSK[136.11].L "sp|Q86U44|MTA70_HUMAN,tr|F5H6D8|F5H6D8_HUMAN,tr|H0YFV6|H0YFV6_HUMAN,tr|B4DTN4|B4DTN4_HUMAN" 4 1804.8471 0.001 85220 16507 2 1804.843123 903.4308 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 5.13 2740.4 - 4.04E+06 - - - -2.2268 - 3.609 0.674 - 1157 1 1 0 -0.004 16 0 0 0 0.00E+00 9.56E+08 - - - 7.1733 1 221125_WJC_METTL3_EV_vs_WT_F06.16518.16518.2 7.65E-07 20/36 R.GLLQDDAHPTLVTYADHSK.L "sp|Q86U44|MTA70_HUMAN,tr|F5H6D8|F5H6D8_HUMAN,tr|H0YFV6|H0YFV6_HUMAN,tr|B4DTN4|B4DTN4_HUMAN" 4 2080.0225 0.01 85225 16518 2 2081.020031 1041.0185 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 5.13 2741.6 - 1.27E+07 - - - 479.5612 - 3.629 0.589 - 818.7 1 2 0 0.9975 19 0 0 0 1.61E+09 1.21E+11 - - - 6.2471 1 221125_WJC_METTL3_EV_vs_WT_F06.16520.16520.2 3.06E-13 24/36 K.PSTASAVPELATDPELEK[136.11]K[136.11].L "sp|Q86U44|MTA70_HUMAN,tr|B4E349|B4E349_HUMAN,tr|F5H6D8|F5H6D8_HUMAN,tr|H0YFV6|H0YFV6_HUMAN,tr|B4DTN4|B4DTN4_HUMAN" 5 1998.0492 0.001 85227 16520 2 1998.042523 1000.0319 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 4.41 2741.8 - 7.37E+06 - - - -3.3428 - 3.664 0.646 - 1170 1 1 0 -0.0067 19 0 0 0 0.00E+00 5.42E+08 - - - 7.0028 1 221125_WJC_METTL3_EV_vs_WT_F06.16541.16541.3 3.58E-09 17/48 D.AHPTLVTYADHSK[136.11].L "sp|Q86U44|MTA70_HUMAN,tr|F5H6D8|F5H6D8_HUMAN,tr|H0YFV6|H0YFV6_HUMAN,tr|B4DTN4|B4DTN4_HUMAN" 4 1446.7347 0.01 85230 16541 3 1446.726321 483.2522 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 6.96 2745 - 6.86E+06 - - - -5.7765 - 3.195 0.617 - 396.9 1 1 0 -0.0084 13 0 0 0 3.97E+06 2.72E+08 - - - 8.566 0.9982 221125_WJC_METTL3_EV_vs_WT_F06.16556.16556.3 6.65E-07 17/60 L.QDDAHPTLVTYADHSK[136.11].L "sp|Q86U44|MTA70_HUMAN,tr|F5H6D8|F5H6D8_HUMAN,tr|H0YFV6|H0YFV6_HUMAN,tr|B4DTN4|B4DTN4_HUMAN" 4 1804.8471 0.01 85231 16556 3 1804.845735 602.623 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 5.13 2747.5 - 6.60E+07 - - - -0.7796 - 2.703 0.556 - 368.7 1 1 0 -0.0014 16 0 0 0 9.21E+07 9.33E+09 - - - 7.2899 0.9994 221125_WJC_METTL3_EV_vs_WT_F06.16599.16599.2 2.96E-08 14/32 K.ANELPQPPVPEPANAGK[136.11].R "sp|P78347|GTF2I_HUMAN,tr|A0A494C1K3|A0A494C1K3_HUMAN" 2 1735.8984 2.29 85236 16599 2 1735.892029 868.9565 General transcription factor II-I OS=Homo sapiens OX=9606 GN=GTF2I PE=1 SV=2 4.53 2754.3 - 4.54E+06 - - - -3.6984 - 2.402 0.592 - 457 1 2 0 -0.0064 17 0 0 0 3.41E+09 1.49E+09 - - - 5.5659 0.995 221125_WJC_METTL3_EV_vs_WT_F06.16606.16606.3 0.000119 18/52 R.LQDEIQNMKEEMAR.H "sp|P08670|VIME_HUMAN,tr|B0YJC5|B0YJC5_HUMAN,tr|B0YJC4|B0YJC4_HUMAN" 3 1733.8077 4.94 85237 16606 3 1733.803869 578.9432 Vimentin OS=Homo sapiens OX=9606 GN=VIM PE=1 SV=4 4.41 2755.4 - 6.70E+06 - - - -2.1836 - 2.881 0.217 - 464.1 1 2 1 -0.0038 14 0 0 0 3.40E+08 6.87E+07 - - - 3.7703 0.9999 221125_WJC_METTL3_EV_vs_WT_F06.16619.16619.2 1.42E-07 15/32 K.ANELPQPPVPEPANAGK.R "sp|P78347|GTF2I_HUMAN,tr|A0A494C1K3|A0A494C1K3_HUMAN" 2 1727.8842 2.33 85239 16619 2 1727.884124 864.9494 General transcription factor II-I OS=Homo sapiens OX=9606 GN=GTF2I PE=1 SV=2 4.53 2757.4 - 1.75E+07 - - - -0.0723 - 2.529 0.588 - 497.5 1 2 0 -0.0001 17 0 0 0 3.70E+09 1.59E+09 - - - 5.665 1 221125_WJC_METTL3_EV_vs_WT_F06.16623.16623.3 6.04E-09 17/56 K.SELLSQLQQHEEESR[166.11].A sp|Q92665|RT31_HUMAN 1 1821.8732 3.02 85240 16623 3 1821.868459 608.2984 "28S ribosomal protein S31, mitochondrial OS=Homo sapiens OX=9606 GN=MRPS31 PE=1 SV=3" 4.48 2757.9 - 7.45E+06 - - - -2.6242 - 3.557 0.618 - 379 1 2 0 -0.0048 15 0 0 0 1.05E+09 3.46E+08 - - - 8.7398 1 221125_WJC_METTL3_EV_vs_WT_F06.16630.16630.3 9.72E-06 17/56 K.SELLSQLQQHEEESR.A sp|Q92665|RT31_HUMAN 1 1811.865 3.03 85241 16630 3 1811.864479 604.9623 "28S ribosomal protein S31, mitochondrial OS=Homo sapiens OX=9606 GN=MRPS31 PE=1 SV=3" 4.48 2759 - 1.58E+07 - - - -0.271 - 3.241 0.583 - 365.3 1 2 0 -0.0005 15 0 0 0 1.05E+09 3.46E+08 - - - 8.108 0.9488 221125_WJC_METTL3_EV_vs_WT_F06.16632.16632.4 0.0189 7/102 G.LLQDDAHPTLVTYADHSK[136.11].L "sp|Q86U44|MTA70_HUMAN,tr|F5H6D8|F5H6D8_HUMAN,tr|H0YFV6|H0YFV6_HUMAN,tr|B4DTN4|B4DTN4_HUMAN" 4 2031.0153 0.04 85242 16632 4 2031.015987 508.7611 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 5.13 2759.2 - 7.95E+06 - - - 0.353 - 1.559 0.348 - 36.4 1 1 0 0.0007 18 0 0 0 3.82E+07 9.05E+08 - - - 2.4069 0.9999 221125_WJC_METTL3_EV_vs_WT_F06.16637.16637.3 1.28E-07 20/64 K.ANELPQPPVPEPANAGK[136.11].R "sp|P78347|GTF2I_HUMAN,tr|A0A494C1K3|A0A494C1K3_HUMAN" 2 1735.8984 2.68 85244 16637 3 1735.894752 579.6401 General transcription factor II-I OS=Homo sapiens OX=9606 GN=GTF2I PE=1 SV=2 4.53 2759.8 - 5.34E+06 - - - -2.1297 - 3.238 0.443 - 525.3 1 2 0 -0.0037 17 0 0 0 1.17E+09 4.38E+08 - - - 6.4463 1 221125_WJC_METTL3_EV_vs_WT_F06.16653.16653.3 5.66E-20 24/96 K.LVQDVANNTNEEAGDGTTTATVLAR.S "sp|P10809|CH60_HUMAN,tr|C9JL25|C9JL25_HUMAN,tr|A0A7I2V2X6|A0A7I2V2X6_HUMAN,tr|A0A7I2YQK6|A0A7I2YQK6_HUMAN,tr|A0A7I2V599|A0A7I2V599_HUMAN,tr|E7EXB4|E7EXB4_HUMAN,tr|A0A7I2YQ71|A0A7I2YQ71_HUMAN,tr|E7ESH4|E7ESH4_HUMAN,tr|A0A7I2V5M1|A0A7I2V5M1_HUMAN,tr|A0A7I2V5K3|A0A7I2V5K3_HUMAN,tr|A0A7I2V369|A0A7I2V369_HUMAN" 11 2559.2413 1.34 85247 16653 3 2559.237455 854.0877 "60 kDa heat shock protein, mitochondrial OS=Homo sapiens OX=9606 GN=HSPD1 PE=1 SV=2" 3.92 2762.2 - 1.16E+07 - - - -1.484 - 4.448 0.703 - 754 1 2 0 -0.0038 25 0 0 0 4.74E+10 3.52E+10 - - - 9.8103 1 221125_WJC_METTL3_EV_vs_WT_F06.16662.16662.3 4.63E-17 23/96 K.LVQDVANNTNEEAGDGTTTATVLAR[166.11].S "sp|P10809|CH60_HUMAN,tr|C9JL25|C9JL25_HUMAN,tr|A0A7I2V2X6|A0A7I2V2X6_HUMAN,tr|A0A7I2YQK6|A0A7I2YQK6_HUMAN,tr|A0A7I2V599|A0A7I2V599_HUMAN,tr|E7EXB4|E7EXB4_HUMAN,tr|A0A7I2YQ71|A0A7I2YQ71_HUMAN,tr|E7ESH4|E7ESH4_HUMAN,tr|A0A7I2V5M1|A0A7I2V5M1_HUMAN,tr|A0A7I2V5K3|A0A7I2V5K3_HUMAN,tr|A0A7I2V369|A0A7I2V369_HUMAN" 11 2569.2495 1.34 85251 16662 3 2569.23974 857.4238 "60 kDa heat shock protein, mitochondrial OS=Homo sapiens OX=9606 GN=HSPD1 PE=1 SV=2" 3.92 2763.2 - 2.94E+07 - - - -3.8077 - 4.161 0.744 - 724.1 1 2 0 -0.0098 25 0 0 0 4.73E+10 3.52E+10 - - - 10.1123 1 221125_WJC_METTL3_EV_vs_WT_F06.16669.16669.2 9.09E-20 27/48 K.LVQDVANNTNEEAGDGTTTATVLAR.S "sp|P10809|CH60_HUMAN,tr|C9JL25|C9JL25_HUMAN,tr|A0A7I2V2X6|A0A7I2V2X6_HUMAN,tr|A0A7I2YQK6|A0A7I2YQK6_HUMAN,tr|A0A7I2V599|A0A7I2V599_HUMAN,tr|E7EXB4|E7EXB4_HUMAN,tr|A0A7I2YQ71|A0A7I2YQ71_HUMAN,tr|E7ESH4|E7ESH4_HUMAN,tr|A0A7I2V5M1|A0A7I2V5M1_HUMAN,tr|A0A7I2V5K3|A0A7I2V5K3_HUMAN,tr|A0A7I2V369|A0A7I2V369_HUMAN" 11 2559.2413 1.49 85252 16669 2 2559.241282 1280.6279 "60 kDa heat shock protein, mitochondrial OS=Homo sapiens OX=9606 GN=HSPD1 PE=1 SV=2" 3.92 2764.3 - 9.89E+06 - - - 0.0113 - 4.911 0.783 - 2027.4 1 2 0 0 25 0 0 0 9.36E+09 6.30E+09 - - - 8.7369 1 221125_WJC_METTL3_EV_vs_WT_F06.16672.16672.2 2.15E-15 30/48 K.LVQDVANNTNEEAGDGTTTATVLAR[166.11].S "sp|P10809|CH60_HUMAN,tr|C9JL25|C9JL25_HUMAN,tr|A0A7I2V2X6|A0A7I2V2X6_HUMAN,tr|A0A7I2YQK6|A0A7I2YQK6_HUMAN,tr|A0A7I2V599|A0A7I2V599_HUMAN,tr|E7EXB4|E7EXB4_HUMAN,tr|A0A7I2YQ71|A0A7I2YQ71_HUMAN,tr|E7ESH4|E7ESH4_HUMAN,tr|A0A7I2V5M1|A0A7I2V5M1_HUMAN,tr|A0A7I2V5K3|A0A7I2V5K3_HUMAN,tr|A0A7I2V369|A0A7I2V369_HUMAN" 11 2569.2495 1.48 85254 16672 2 2569.248227 1285.632 "60 kDa heat shock protein, mitochondrial OS=Homo sapiens OX=9606 GN=HSPD1 PE=1 SV=2" 3.92 2764.6 - 8.64E+06 - - - -0.5044 - 5.382 0.748 - 3118.1 1 2 0 -0.0013 25 0 0 0 9.34E+09 6.29E+09 - - - 8.7032 1 221125_WJC_METTL3_EV_vs_WT_F06.16679.16679.4 1.36E-10 20/144 K.LVQDVANNTNEEAGDGTTTATVLAR[166.11].S "sp|P10809|CH60_HUMAN,tr|C9JL25|C9JL25_HUMAN,tr|A0A7I2V2X6|A0A7I2V2X6_HUMAN,tr|A0A7I2YQK6|A0A7I2YQK6_HUMAN,tr|A0A7I2V599|A0A7I2V599_HUMAN,tr|E7EXB4|E7EXB4_HUMAN,tr|A0A7I2YQ71|A0A7I2YQ71_HUMAN,tr|E7ESH4|E7ESH4_HUMAN,tr|A0A7I2V5M1|A0A7I2V5M1_HUMAN,tr|A0A7I2V5K3|A0A7I2V5K3_HUMAN,tr|A0A7I2V369|A0A7I2V369_HUMAN" 11 2569.2495 1.23 85256 16679 4 2569.243726 643.3197 "60 kDa heat shock protein, mitochondrial OS=Homo sapiens OX=9606 GN=HSPD1 PE=1 SV=2" 3.92 2765.6 - 1.55E+07 - - - -2.2563 - 3.194 0.611 - 304.3 1 2 0 -0.0058 25 0 0 0 3.15E+09 2.57E+09 - - - 4.912 1 221125_WJC_METTL3_EV_vs_WT_F06.16696.16696.2 1.20E-13 25/36 R.GLLQDDAHPTLVTYADHSK[136.11].L "sp|Q86U44|MTA70_HUMAN,tr|F5H6D8|F5H6D8_HUMAN,tr|H0YFV6|H0YFV6_HUMAN,tr|B4DTN4|B4DTN4_HUMAN" 4 2088.0367 0.01 85262 16696 2 2088.030747 1045.0256 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 5.13 2767.7 - 2.14E+08 - - - -2.8668 - 4.412 0.752 - 1548.3 1 2 0 -0.006 19 0 0 0 1.61E+09 1.21E+11 - - - 8.2427 1 221125_WJC_METTL3_EV_vs_WT_F06.16698.16698.3 4.98E-12 21/64 K.ANELPQPPVPEPANAGK.R "sp|P78347|GTF2I_HUMAN,tr|A0A494C1K3|A0A494C1K3_HUMAN" 2 1727.8842 2.68 85263 16698 3 1727.882539 576.9687 General transcription factor II-I OS=Homo sapiens OX=9606 GN=GTF2I PE=1 SV=2 4.53 2767.9 - 1.37E+07 - - - -0.9896 - 3.911 0.649 - 563.3 1 2 0 -0.0017 17 0 0 0 1.17E+09 4.38E+08 - - - 9.2206 0.9859 221125_WJC_METTL3_EV_vs_WT_F06.16701.16701.4 0.00255 14/96 L.LQDDAHPTLVTYADHSK[136.11].L "sp|Q86U44|MTA70_HUMAN,tr|F5H6D8|F5H6D8_HUMAN,tr|H0YFV6|H0YFV6_HUMAN,tr|B4DTN4|B4DTN4_HUMAN" 4 1917.9312 0.01 85264 16701 4 1917.926931 480.4901 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 5.13 2768.3 - 1.49E+07 - - - -2.229 - 2.136 0.452 - 135.9 1 1 0 -0.0043 17 0 0 0 2.62E+07 3.35E+09 - - - 3.4225 0.9954 221125_WJC_METTL3_EV_vs_WT_F06.16712.16712.3 9.68E-06 16/72 R.GLLQDDAHPTLVTYADHSK.L "sp|Q86U44|MTA70_HUMAN,tr|F5H6D8|F5H6D8_HUMAN,tr|H0YFV6|H0YFV6_HUMAN,tr|B4DTN4|B4DTN4_HUMAN" 4 2080.0225 0.02 85267 16712 3 2081.020551 694.3481 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 5.13 2769.8 - 3.57E+07 - - - 479.8111 - 2.574 0.462 - 197 1 2 0 0.998 19 0 0 0 1.17E+10 5.29E+11 - - - 5.7372 0.9999 221125_WJC_METTL3_EV_vs_WT_F06.16714.16714.4 6.10E-05 13/144 K.LVQDVANNTNEEAGDGTTTATVLAR.S "sp|P10809|CH60_HUMAN,tr|C9JL25|C9JL25_HUMAN,tr|A0A7I2V2X6|A0A7I2V2X6_HUMAN,tr|A0A7I2YQK6|A0A7I2YQK6_HUMAN,tr|A0A7I2V599|A0A7I2V599_HUMAN,tr|E7EXB4|E7EXB4_HUMAN,tr|A0A7I2YQ71|A0A7I2YQ71_HUMAN,tr|E7ESH4|E7ESH4_HUMAN,tr|A0A7I2V5M1|A0A7I2V5M1_HUMAN,tr|A0A7I2V5K3|A0A7I2V5K3_HUMAN,tr|A0A7I2V369|A0A7I2V369_HUMAN" 11 2559.2413 1.23 85269 16714 4 2559.238349 640.8176 "60 kDa heat shock protein, mitochondrial OS=Homo sapiens OX=9606 GN=HSPD1 PE=1 SV=2" 3.92 2769.9 - 9.58E+07 - - - -1.1347 - 2.41 0.472 - 102 1 2 0 -0.0029 25 0 0 0 3.15E+09 2.56E+09 - - - 3.6133 0.9631 221125_WJC_METTL3_EV_vs_WT_F06.16722.16722.3 6.40E-09 22/56 Q.DDAHPTLVTYADHSK[136.11].L "sp|Q86U44|MTA70_HUMAN,tr|F5H6D8|F5H6D8_HUMAN,tr|H0YFV6|H0YFV6_HUMAN,tr|B4DTN4|B4DTN4_HUMAN" 4 1676.7886 0.01 85274 16722 3 1676.778299 559.9368 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 5.13 2770.7 - 6.15E+06 - - - -6.1218 - 3.094 0.605 - 326.6 1 1 0 -0.0103 15 0 0 0 1.79E+07 2.17E+09 - - - 8.2295 0.9981 221125_WJC_METTL3_EV_vs_WT_F06.16730.16730.2 3.09E-06 19/32 K.SQVFSTAADGQTQVEIK[136.11].V "sp|P38646|GRP75_HUMAN,tr|A0A7I2V2S7|A0A7I2V2S7_HUMAN,tr|A0A7I2V2G2|A0A7I2V2G2_HUMAN,tr|A0A7I2YQB2|A0A7I2YQB2_HUMAN,tr|D6RCD7|D6RCD7_HUMAN" 5 1815.9094 0.04 85278 16730 2 1815.918775 908.962 "Stress-70 protein, mitochondrial OS=Homo sapiens OX=9606 GN=HSPA9 PE=1 SV=2" 4.37 2771.6 - 5.51E+06 - - - 5.1583 - 3.374 0.481 - 809.1 1 2 0 0.0094 17 0 0 0 6.10E+06 1.44E+08 - - - 5.5806 1 221125_WJC_METTL3_EV_vs_WT_F06.16739.16739.3 8.38E-09 20/56 K.AADHLK[136.11]PFLDDSTLR[166.11].F sp|O43395|PRPF3_HUMAN 1 1715.8962 2.17 85283 16739 3 1715.89353 572.9727 U4\U6 small nuclear ribonucleoprotein Prp3 OS=Homo sapiens OX=9606 GN=PRPF3 PE=1 SV=2 5.3 2772.6 - 3.78E+06 - - - -1.5292 - 3.44 0.592 - 632.6 1 2 0 -0.0026 15 0 0 0 6.26E+08 2.88E+08 - - - 8.3633 1 221125_WJC_METTL3_EV_vs_WT_F06.16743.16743.3 1.77E-09 16/56 K.AADHLKPFLDDSTLR.F sp|O43395|PRPF3_HUMAN 1 1697.8737 2.16 85286 16743 3 1697.87497 566.9652 U4\U6 small nuclear ribonucleoprotein Prp3 OS=Homo sapiens OX=9606 GN=PRPF3 PE=1 SV=2 5.3 2772.9 - 9.90E+06 - - - 0.7574 - 3.156 0.597 - 383.3 1 2 0 0.0013 15 0 0 0 6.26E+08 2.89E+08 - - - 8.1946 1 221125_WJC_METTL3_EV_vs_WT_F06.16750.16750.2 3.28E-13 23/30 L.QDDAHPTLVTYADHSK[136.11].L "sp|Q86U44|MTA70_HUMAN,tr|F5H6D8|F5H6D8_HUMAN,tr|H0YFV6|H0YFV6_HUMAN,tr|B4DTN4|B4DTN4_HUMAN" 4 1804.8471 0.001 85288 16750 2 1804.843094 903.4308 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 5.13 2773.9 - 2.69E+06 - - - -2.2428 - 3.679 0.667 - 1403.7 1 1 0 -0.004 16 0 0 0 0.00E+00 1.37E+08 - - - 7.1688 1 221125_WJC_METTL3_EV_vs_WT_F06.16752.16752.4 3.84E-08 16/84 K.AADHLKPFLDDSTLR.F sp|O43395|PRPF3_HUMAN 1 1697.8737 2.97 85289 16752 4 1697.874251 425.4757 U4\U6 small nuclear ribonucleoprotein Prp3 OS=Homo sapiens OX=9606 GN=PRPF3 PE=1 SV=2 5.3 2774.1 - 5.71E+06 - - - 0.3339 - 3.093 0.528 - 230 1 2 0 0.0006 15 0 0 0 2.98E+08 1.00E+08 - - - 4.2256 1 221125_WJC_METTL3_EV_vs_WT_F06.16766.16766.3 3.31E-08 32/128 K.LASVPAGGAVAVSAAPGSAAPAAGSAPAAAEEK.K "sp|P05387|RLA2_HUMAN,tr|H0YDD8|H0YDD8_HUMAN" 2 2773.4246 1.54 85294 16766 3 2773.419 925.4822 60S acidic ribosomal protein P2 OS=Homo sapiens OX=9606 GN=RPLP2 PE=1 SV=1 4.53 2775.9 - 1.52E+07 - - - -2.0325 - 4.355 0.622 - 621.8 1 2 0 -0.0056 33 0 0 0 1.05E+10 6.81E+09 - - - 8.8581 1 221125_WJC_METTL3_EV_vs_WT_F06.16770.16770.4 5.47E-07 17/108 R.VIHLSNLPHSGYSDSAVLK.L "sp|P43243|MATR3_HUMAN,tr|B3KM87|B3KM87_HUMAN,tr|A8MXP9|A8MXP9_HUMAN,tr|D6RBK5|D6RBK5_HUMAN,tr|A0A0R4J2E8|A0A0R4J2E8_HUMAN,tr|H0Y8T4|H0Y8T4_HUMAN,tr|D6REM6|D6REM6_HUMAN" 7 2036.0691 1.36 85296 16770 4 2036.067095 510.0245 Matrin-3 OS=Homo sapiens OX=9606 GN=MATR3 PE=1 SV=2 6.89 2776.3 - 1.68E+07 - - - -0.9798 - 3.245 0.536 - 253.8 1 2 0 -0.002 19 0 0 0 3.19E+10 2.34E+10 - - - 4.289 1 221125_WJC_METTL3_EV_vs_WT_F06.16771.16771.4 5.30E-08 15/108 R.VIHLSNLPHSGYSDSAVLK[136.11].L "sp|P43243|MATR3_HUMAN,tr|B3KM87|B3KM87_HUMAN,tr|A8MXP9|A8MXP9_HUMAN,tr|D6RBK5|D6RBK5_HUMAN,tr|A0A0R4J2E8|A0A0R4J2E8_HUMAN,tr|H0Y8T4|H0Y8T4_HUMAN,tr|D6REM6|D6REM6_HUMAN" 7 2044.0833 1.36 85297 16771 4 2044.081696 512.0281 Matrin-3 OS=Homo sapiens OX=9606 GN=MATR3 PE=1 SV=2 6.89 2776.4 - 1.11E+07 - - - -0.7798 - 2.992 0.6 - 210.7 1 2 0 -0.0016 19 0 0 0 3.19E+10 2.34E+10 - - - 4.8187 1 221125_WJC_METTL3_EV_vs_WT_F06.16775.16775.3 3.34E-11 30/72 R.VIHLSNLPHSGYSDSAVLK.L "sp|P43243|MATR3_HUMAN,tr|B3KM87|B3KM87_HUMAN,tr|A8MXP9|A8MXP9_HUMAN,tr|D6RBK5|D6RBK5_HUMAN,tr|A0A0R4J2E8|A0A0R4J2E8_HUMAN,tr|H0Y8T4|H0Y8T4_HUMAN,tr|D6REM6|D6REM6_HUMAN" 7 2036.0691 1.31 85299 16775 3 2036.069976 679.697 Matrin-3 OS=Homo sapiens OX=9606 GN=MATR3 PE=1 SV=2 6.89 2776.8 - 1.08E+07 - - - 0.4352 - 4.81 0.68 - 1293.4 1 2 0 0.0009 19 0 0 0 1.46E+10 1.12E+10 - - - 9.98 1 221125_WJC_METTL3_EV_vs_WT_F06.16778.16778.3 1.13E-05 20/72 R.VIHLSNLPHSGYSDSAVLK[136.11].L "sp|P43243|MATR3_HUMAN,tr|B3KM87|B3KM87_HUMAN,tr|A8MXP9|A8MXP9_HUMAN,tr|D6RBK5|D6RBK5_HUMAN,tr|A0A0R4J2E8|A0A0R4J2E8_HUMAN,tr|H0Y8T4|H0Y8T4_HUMAN,tr|D6REM6|D6REM6_HUMAN" 7 2044.0833 1.31 85301 16778 3 2044.084235 682.3684 Matrin-3 OS=Homo sapiens OX=9606 GN=MATR3 PE=1 SV=2 6.89 2777.1 - 1.00E+07 - - - 0.4623 - 3.743 0.583 - 476.4 1 2 0 0.0009 19 0 0 0 1.46E+10 1.12E+10 - - - 8.2823 1 221125_WJC_METTL3_EV_vs_WT_F06.16779.16779.2 5.98E-08 24/36 R.GLLQDDAHPTLVTYADHSK.L "sp|Q86U44|MTA70_HUMAN,tr|F5H6D8|F5H6D8_HUMAN,tr|H0YFV6|H0YFV6_HUMAN,tr|B4DTN4|B4DTN4_HUMAN" 4 2080.0225 0.01 85302 16779 2 2081.015636 1041.0185 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 5.13 2777.2 - 4.44E+06 - - - 477.4482 - 3.696 0.629 - 1099.1 1 2 0 0.9931 19 0 0 0 1.61E+09 1.21E+11 - - - 6.5889 0.9951 221125_WJC_METTL3_EV_vs_WT_F06.16789.16789.3 1.13E-07 19/60 L.QDDAHPTLVTYADHSK[136.11].L "sp|Q86U44|MTA70_HUMAN,tr|F5H6D8|F5H6D8_HUMAN,tr|H0YFV6|H0YFV6_HUMAN,tr|B4DTN4|B4DTN4_HUMAN" 4 1804.8471 0.02 85306 16789 3 1804.842234 602.623 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 5.13 2778.5 - 3.37E+07 - - - -2.7193 - 2.796 0.564 - 468.9 1 1 0 -0.0049 16 0 0 0 3.12E+07 1.81E+09 - - - 7.4649 1 221125_WJC_METTL3_EV_vs_WT_F06.16793.16793.2 3.98E-10 30/64 K.LASVPAGGAVAVSAAPGSAAPAAGSAPAAAEEK.K "sp|P05387|RLA2_HUMAN,tr|H0YDD8|H0YDD8_HUMAN" 2 2773.4246 2.41 85308 16793 2 2773.423524 1387.7196 60S acidic ribosomal protein P2 OS=Homo sapiens OX=9606 GN=RPLP2 PE=1 SV=1 4.53 2778.9 - 1.43E+07 - - - -0.4013 - 4.49 0.696 - 1158.6 1 2 0 -0.0011 33 0 0 0 8.66E+08 3.59E+08 - - - 7.8737 0.9978 221125_WJC_METTL3_EV_vs_WT_F06.16799.16799.3 2.63E-08 18/64 L.LQDDAHPTLVTYADHSK[136.11].L "sp|Q86U44|MTA70_HUMAN,tr|F5H6D8|F5H6D8_HUMAN,tr|H0YFV6|H0YFV6_HUMAN,tr|B4DTN4|B4DTN4_HUMAN" 4 1917.9312 0.02 85311 16799 3 1917.927721 640.3177 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 5.13 2779.6 - 5.56E+07 - - - -1.8171 - 3.074 0.569 - 419.4 1 1 0 -0.0035 17 0 0 0 1.81E+08 8.57E+09 - - - 7.7198 1 221125_WJC_METTL3_EV_vs_WT_F06.16803.16803.3 6.77E-06 26/56 K.HLEINPDHPIVETLR.Q sp|P08238|HS90B_HUMAN 1 1781.9424 1.22 85313 16803 3 1781.940304 594.9881 Heat shock protein HSP 90-beta OS=Homo sapiens OX=9606 GN=HSP90AB1 PE=1 SV=4 5.27 2780 - 6.78E+06 - - - -1.1948 - 4.52 0.588 - 1067.9 1 2 0 -0.0021 15 0 0 0 3.69E+08 3.02E+08 - - - 9.0313 1 221125_WJC_METTL3_EV_vs_WT_F06.16805.16805.2 1.71E-10 20/28 Q.DDAHPTLVTYADHSK[136.11].L "sp|Q86U44|MTA70_HUMAN,tr|F5H6D8|F5H6D8_HUMAN,tr|H0YFV6|H0YFV6_HUMAN,tr|B4DTN4|B4DTN4_HUMAN" 4 1676.7886 0.01 85314 16805 2 1676.782579 839.4016 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 5.13 2780.2 - 3.43E+06 - - - -3.5693 - 3.516 0.67 - 1056.2 1 1 0 -0.006 15 0 0 0 2.00E+06 1.79E+08 - - - 7.0789 0.9951 221125_WJC_METTL3_EV_vs_WT_F06.16809.16809.3 5.32E-08 17/48 D.AHPTLVTYADHSK[136.11].L "sp|Q86U44|MTA70_HUMAN,tr|F5H6D8|F5H6D8_HUMAN,tr|H0YFV6|H0YFV6_HUMAN,tr|B4DTN4|B4DTN4_HUMAN" 4 1446.7347 0.56 85316 16809 3 1446.73044 483.2522 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 6.96 2780.7 - 1.17E+06 - - - -2.9294 - 3.02 0.555 - 438.5 1 1 0 -0.0042 13 0 0 0 3.63E+07 6.48E+07 - - - 7.7232 1 221125_WJC_METTL3_EV_vs_WT_F06.16811.16811.2 1.16E-11 29/64 K.LASVPAGGAVAVSAAPGSAAPAAGSAPAAAEEK[136.11].K "sp|P05387|RLA2_HUMAN,tr|H0YDD8|H0YDD8_HUMAN" 2 2781.4388 2.41 85317 16811 2 2782.433754 1391.7267 60S acidic ribosomal protein P2 OS=Homo sapiens OX=9606 GN=RPLP2 PE=1 SV=1 4.53 2780.9 - 1.14E+07 - - - 357.6987 - 4.111 0.693 - 1141.6 1 2 0 0.9949 33 0 0 0 8.66E+08 3.59E+08 - - - 7.3227 0.9999 221125_WJC_METTL3_EV_vs_WT_F06.16813.16813.4 1.82E-10 27/192 K.LASVPAGGAVAVSAAPGSAAPAAGSAPAAAEEK.K "sp|P05387|RLA2_HUMAN,tr|H0YDD8|H0YDD8_HUMAN" 2 2773.4246 3.17 85318 16813 4 2773.414858 694.3634 60S acidic ribosomal protein P2 OS=Homo sapiens OX=9606 GN=RPLP2 PE=1 SV=1 4.53 2781.2 - 9.81E+07 - - - -3.526 - 4.109 0.597 - 325.6 1 2 0 -0.0098 33 0 0 0 2.82E+09 8.92E+08 - - - 4.8436 1 221125_WJC_METTL3_EV_vs_WT_F06.16814.16814.3 3.76E-06 27/56 K.HLEINPDHPIVETLR[166.11].Q sp|P08238|HS90B_HUMAN 1 1791.9507 1.23 85319 16814 3 1791.950562 598.3242 Heat shock protein HSP 90-beta OS=Homo sapiens OX=9606 GN=HSP90AB1 PE=1 SV=4 5.27 2781.2 - 4.10E+06 - - - -0.0787 - 3.695 0.547 - 1088.9 1 2 0 -0.0001 15 0 0 0 3.70E+08 3.02E+08 - - - 8.0489 0.9999 221125_WJC_METTL3_EV_vs_WT_F06.16823.16823.3 7.16E-05 14/44 K.SDQWKPLNLEEK.K "sp|Q04637|IF4G1_HUMAN,tr|C9J2Z7|C9J2Z7_HUMAN,tr|E7EUU4|E7EUU4_HUMAN,tr|E9PGM1|E9PGM1_HUMAN,tr|C9J6B6|C9J6B6_HUMAN,tr|E7EX73|E7EX73_HUMAN,tr|C9K073|C9K073_HUMAN,tr|A0A7I2Y1C3|A0A7I2Y1C3_HUMAN,tr|C9JF13|C9JF13_HUMAN,tr|A0A6Q8PFB2|A0A6Q8PFB2_HUMAN" 10 1485.7464 1.72 85321 16823 3 1485.743454 496.2561 Eukaryotic translation initiation factor 4 gamma 1 OS=Homo sapiens OX=9606 GN=EIF4G1 PE=1 SV=4 4.68 2782.4 - 2.93E+06 - - - -1.9546 - 2.714 0.437 - 255.8 1 2 0 -0.0029 12 0 0 0 1.50E+08 8.72E+07 - - - 6.1788 0.9999 221125_WJC_METTL3_EV_vs_WT_F06.16825.16825.3 0.000209 13/44 K.SDQWK[136.11]PLNLEEK[136.11].K "sp|Q04637|IF4G1_HUMAN,tr|C9J2Z7|C9J2Z7_HUMAN,tr|E7EUU4|E7EUU4_HUMAN,tr|E9PGM1|E9PGM1_HUMAN,tr|C9J6B6|C9J6B6_HUMAN,tr|E7EX73|E7EX73_HUMAN,tr|C9K073|C9K073_HUMAN,tr|A0A7I2Y1C3|A0A7I2Y1C3_HUMAN,tr|C9JF13|C9JF13_HUMAN,tr|A0A6Q8PFB2|A0A6Q8PFB2_HUMAN" 10 1501.7748 1.62 85322 16825 3 1501.772597 501.5989 Eukaryotic translation initiation factor 4 gamma 1 OS=Homo sapiens OX=9606 GN=EIF4G1 PE=1 SV=4 4.68 2782.7 - 2.72E+06 - - - -1.439 - 2.625 0.373 - 197.6 1 2 0 -0.0022 12 0 0 0 1.41E+08 8.72E+07 - - - 5.373 1 221125_WJC_METTL3_EV_vs_WT_F06.16826.16826.3 6.12E-06 20/60 K.NLPQDSNC[160.03]QEVHDLLK.D sp|Q9HCJ3|RAVR2_HUMAN 1 1908.9 0.06 85323 16826 3 1908.898838 637.3073 Ribonucleoprotein PTB-binding 2 OS=Homo sapiens OX=9606 GN=RAVER2 PE=1 SV=2 4.54 2782.8 - 1.67E+06 - - - -0.5962 - 2.461 0.465 - 299.7 1 2 0 -0.0011 16 0 0 0 1.22E+08 1.90E+09 - - - 6.0347 1 221125_WJC_METTL3_EV_vs_WT_F06.16829.16829.2 0.039 22/36 R.VIHLSNLPHSGYSDSAVLK.L "sp|P43243|MATR3_HUMAN,tr|B3KM87|B3KM87_HUMAN,tr|A8MXP9|A8MXP9_HUMAN,tr|D6RBK5|D6RBK5_HUMAN,tr|A0A0R4J2E8|A0A0R4J2E8_HUMAN,tr|H0Y8T4|H0Y8T4_HUMAN,tr|D6REM6|D6REM6_HUMAN" 7 2036.0691 1.37 85326 16829 2 2036.063508 1019.0418 Matrin-3 OS=Homo sapiens OX=9606 GN=MATR3 PE=1 SV=2 6.89 2782.9 - 4.82E+06 - - - -2.7416 - 4.034 0.594 - 892.7 1 2 0 -0.0056 19 0 0 0 6.16E+08 4.48E+08 - - - 6.8556 1 221125_WJC_METTL3_EV_vs_WT_F06.16831.16831.2 4.54E-17 31/34 A.PGSAAPAAGSAPAAAEEK.K "sp|P05387|RLA2_HUMAN,tr|H0YDD8|H0YDD8_HUMAN" 2 1551.7529 31.61 85328 16831 2 1551.748984 776.8837 60S acidic ribosomal protein P2 OS=Homo sapiens OX=9606 GN=RPLP2 PE=1 SV=1 4.53 2783.2 - 2.91E+06 - - - -2.5236 - 5.121 0.736 - 3006 1 1 0 -0.0039 18 0 0 0 7.22E+08 2.29E+07 - - - 8.4915 1 221125_WJC_METTL3_EV_vs_WT_F06.16840.16840.2 0.319 19/36 R.VIHLSNLPHSGYSDSAVLK[136.11].L "sp|P43243|MATR3_HUMAN,tr|B3KM87|B3KM87_HUMAN,tr|A8MXP9|A8MXP9_HUMAN,tr|D6RBK5|D6RBK5_HUMAN,tr|A0A0R4J2E8|A0A0R4J2E8_HUMAN,tr|H0Y8T4|H0Y8T4_HUMAN,tr|D6REM6|D6REM6_HUMAN" 7 2044.0833 1.38 85331 16840 2 2044.081992 1023.0489 Matrin-3 OS=Homo sapiens OX=9606 GN=MATR3 PE=1 SV=2 6.89 2784.4 - 4.89E+06 - - - -0.635 - 3.796 0.582 - 610.5 1 2 0 -0.0013 19 0 0 0 6.22E+08 4.50E+08 - - - 6.6188 1 221125_WJC_METTL3_EV_vs_WT_F06.16843.16843.3 1.75E-08 23/72 R.GLLQDDAHPTLVTYADHSK[136.11].L "sp|Q86U44|MTA70_HUMAN,tr|F5H6D8|F5H6D8_HUMAN,tr|H0YFV6|H0YFV6_HUMAN,tr|B4DTN4|B4DTN4_HUMAN" 4 2088.0367 0.01 85332 16843 3 2088.031768 697.0195 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 5.13 2784.8 - 4.30E+08 - - - -2.3778 - 4.128 0.642 - 604.3 1 2 0 -0.005 19 0 0 0 1.02E+09 7.90E+10 - - - 9.1795 0.9914 221125_WJC_METTL3_EV_vs_WT_F06.16845.16845.4 2.26E-06 15/84 K.HLEINPDHPIVETLR[166.11].Q sp|P08238|HS90B_HUMAN 1 1791.9507 1.28 85334 16845 4 1792.94763 448.995 Heat shock protein HSP 90-beta OS=Homo sapiens OX=9606 GN=HSP90AB1 PE=1 SV=4 5.27 2785 - 3.07E+06 - - - 556.3362 - 2.505 0.49 - 255.4 1 2 0 0.9969 15 0 0 0 1.04E+08 8.13E+07 - - - 3.5434 1 221125_WJC_METTL3_EV_vs_WT_F06.16850.16850.4 2.89E-06 21/84 K.HLEINPDHPIVETLR.Q sp|P08238|HS90B_HUMAN 1 1781.9424 1.28 85336 16850 4 1781.939316 446.4929 Heat shock protein HSP 90-beta OS=Homo sapiens OX=9606 GN=HSP90AB1 PE=1 SV=4 5.27 2785.7 - 2.01E+06 - - - -1.7492 - 3.52 0.545 - 450.2 1 2 0 -0.0031 15 0 0 0 1.04E+08 8.13E+07 - - - 4.4191 1 221125_WJC_METTL3_EV_vs_WT_F06.16853.16853.2 1.50E-16 18/38 R.FSSC[160.03]GGGGGSFGAGGGFGSR.S sp|P04264|K2C1_HUMAN 1 1764.7274 999 85339 16853 2 1764.726418 883.371 "Keratin, type II cytoskeletal 1 OS=Homo sapiens OX=9606 GN=KRT1 PE=1 SV=6" 8.25 2786 - 1.83E+06 - - - -0.574 - 4.158 0.77 - 1042.4 1 2 0 -0.001 20 0 0 0 1.58E+08 0.00E+00 - - - 8.2314 1 221125_WJC_METTL3_EV_vs_WT_F06.16858.16858.3 1.23E-07 21/52 R.ADATNVNNWHWTER.D "sp|O95433|AHSA1_HUMAN,tr|G3V3W9|G3V3W9_HUMAN" 2 1712.7655 1.16 85340 16858 3 1712.762641 571.9291 Activator of 90 kDa heat shock protein ATPase homolog 1 OS=Homo sapiens OX=9606 GN=AHSA1 PE=1 SV=1 5.32 2786.7 - 2.37E+06 - - - -1.6873 - 3.815 0.59 - 996.7 1 2 0 -0.0029 14 0 0 0 1.59E+08 1.36E+08 - - - 8.6754 1 221125_WJC_METTL3_EV_vs_WT_F06.16869.16869.3 9.88E-07 15/52 R.ADATNVNNWHWTER[166.11].D "sp|O95433|AHSA1_HUMAN,tr|G3V3W9|G3V3W9_HUMAN" 2 1722.7738 1.16 85343 16869 3 1722.770476 575.2652 Activator of 90 kDa heat shock protein ATPase homolog 1 OS=Homo sapiens OX=9606 GN=AHSA1 PE=1 SV=1 5.32 2788.2 - 3.41E+06 - - - -1.93 - 2.945 0.563 - 428.4 1 2 0 -0.0033 14 0 0 0 1.59E+08 1.36E+08 - - - 7.6864 1 221125_WJC_METTL3_EV_vs_WT_F06.16874.16874.2 9.71E-07 20/22 L.PHSGYSDSAVLK[136.11].L "sp|P43243|MATR3_HUMAN,tr|B3KM87|B3KM87_HUMAN,tr|A8MXP9|A8MXP9_HUMAN,tr|D6RBK5|D6RBK5_HUMAN,tr|A0A0R4J2E8|A0A0R4J2E8_HUMAN,tr|H0Y8T4|H0Y8T4_HUMAN,tr|D6REM6|D6REM6_HUMAN" 7 1267.6288 1.44 85346 16874 2 1267.630077 634.8217 Matrin-3 OS=Homo sapiens OX=9606 GN=MATR3 PE=1 SV=2 7.16 2788.8 - 1.76E+06 - - - 0.9948 - 2.983 0.616 - 1133.4 1 1 0 0.0013 12 0 0 0 9.83E+07 6.81E+07 - - - 6.4661 1 221125_WJC_METTL3_EV_vs_WT_F06.16875.16875.4 2.04E-06 11/108 R.GLLQDDAHPTLVTYADHSK[136.11].L "sp|Q86U44|MTA70_HUMAN,tr|F5H6D8|F5H6D8_HUMAN,tr|H0YFV6|H0YFV6_HUMAN,tr|B4DTN4|B4DTN4_HUMAN" 4 2088.0367 0.02 85347 16875 4 2088.032864 523.0165 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 5.13 2788.9 - 4.32E+08 - - - -1.8529 - 2.368 0.557 - 108.8 1 2 0 -0.0039 19 0 0 0 3.22E+09 1.30E+11 - - - 4.3647 1 221125_WJC_METTL3_EV_vs_WT_F06.16880.16880.3 1.20E-10 22/68 K.AGAK[136.11]PDQIGIITPYEGQR[166.11].S sp|Q92900|RENT1_HUMAN 1 1931.0231 1.16 85349 16880 3 1931.021861 644.6817 Regulator of nonsense transcripts 1 OS=Homo sapiens OX=9606 GN=UPF1 PE=1 SV=2 6.11 2789.4 - 2.43E+06 - - - -0.6655 - 3.802 0.585 - 540.4 1 2 0 -0.0013 18 0 0 0 2.25E+08 1.94E+08 - - - 8.3874 1 221125_WJC_METTL3_EV_vs_WT_F06.16881.16881.3 7.54E-10 22/56 R.GPSLNPVLDYDHGSR.S "sp|P43243|MATR3_HUMAN,tr|A8MXP9|A8MXP9_HUMAN,tr|D6R991|D6R991_HUMAN,tr|A0A0R4J2E8|A0A0R4J2E8_HUMAN,tr|D6REM6|D6REM6_HUMAN" 5 1625.7798 1.33 85350 16881 3 1625.78325 542.9339 Matrin-3 OS=Homo sapiens OX=9606 GN=MATR3 PE=1 SV=2 5.21 2789.6 - 3.17E+06 - - - 2.1319 - 3.531 0.609 - 942.2 1 2 0 0.0035 15 0 0 0 3.16E+08 2.37E+08 - - - 8.6207 1 221125_WJC_METTL3_EV_vs_WT_F06.16883.16883.2 1.68E-06 17/22 L.PHSGYSDSAVLK.L "sp|P43243|MATR3_HUMAN,tr|B3KM87|B3KM87_HUMAN,tr|A8MXP9|A8MXP9_HUMAN,tr|D6RBK5|D6RBK5_HUMAN,tr|A0A0R4J2E8|A0A0R4J2E8_HUMAN,tr|H0Y8T4|H0Y8T4_HUMAN,tr|D6REM6|D6REM6_HUMAN" 7 1259.6146 1.44 85352 16883 2 1259.610336 630.8146 Matrin-3 OS=Homo sapiens OX=9606 GN=MATR3 PE=1 SV=2 7.16 2789.7 - 3.33E+06 - - - -3.3979 - 3.369 0.634 - 794.2 1 1 0 -0.0043 12 0 0 0 9.83E+07 6.81E+07 - - - 6.9182 1 221125_WJC_METTL3_EV_vs_WT_F06.16889.16889.3 5.06E-08 16/56 R.GPSLNPVLDYDHGSR[166.11].S "sp|P43243|MATR3_HUMAN,tr|A8MXP9|A8MXP9_HUMAN,tr|D6R991|D6R991_HUMAN,tr|A0A0R4J2E8|A0A0R4J2E8_HUMAN,tr|D6REM6|D6REM6_HUMAN" 5 1635.7881 1.32 85356 16889 3 1635.785281 546.27 Matrin-3 OS=Homo sapiens OX=9606 GN=MATR3 PE=1 SV=2 5.21 2790.4 - 3.58E+06 - - - -1.6952 - 3.048 0.55 - 380.4 1 2 0 -0.0028 15 0 0 0 3.16E+08 2.39E+08 - - - 7.5793 1 221125_WJC_METTL3_EV_vs_WT_F06.16895.16895.3 1.36E-05 16/68 K.YVHYEIDAC[160.03]MDSEAPGSK[136.11].D "sp|Q86U44|MTA70_HUMAN,tr|H0YFV6|H0YFV6_HUMAN" 2 2078.8805 0 85360 16895 3 2078.876571 693.9674 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 4.31 2791 - 1.67E+07 - - - -1.8861 - 3.135 0.582 - 262.6 1 2 0 -0.0039 18 0 0 0 5.48E+06 1.31E+09 - - - 7.8729 0.9999 221125_WJC_METTL3_EV_vs_WT_F06.16899.16899.3 1.12E-07 15/40 K.TSMESLIHHFK.L "sp|O75306|NDUS2_HUMAN,tr|A0A7I2V4X8|A0A7I2V4X8_HUMAN,tr|A0A7I2V4G5|A0A7I2V4G5_HUMAN,tr|A0A7I2YQG7|A0A7I2YQG7_HUMAN,tr|A0A7I2V596|A0A7I2V596_HUMAN,tr|A0A7I2YQD8|A0A7I2YQD8_HUMAN" 6 1328.6547 0.94 85362 16899 3 1328.65145 443.8922 "NADH dehydrogenase [ubiquinone] iron-sulfur protein 2, mitochondrial OS=Homo sapiens OX=9606 GN=NDUFS2 PE=1 SV=2" 6.61 2791.5 - 1.52E+06 - - - -2.4514 - 2.576 0.482 - 355.4 1 2 0 -0.0033 11 0 0 0 5.35E+07 5.69E+07 - - - 6.601 1 221125_WJC_METTL3_EV_vs_WT_F06.16900.16900.3 3.04E-06 16/40 K.TSMESLIHHFK[136.11].L "sp|O75306|NDUS2_HUMAN,tr|A0A7I2V4X8|A0A7I2V4X8_HUMAN,tr|A0A7I2V4G5|A0A7I2V4G5_HUMAN,tr|A0A7I2YQG7|A0A7I2YQG7_HUMAN,tr|A0A7I2V596|A0A7I2V596_HUMAN,tr|A0A7I2YQD8|A0A7I2YQD8_HUMAN" 6 1336.6689 0.94 85363 16900 3 1336.665601 446.5636 "NADH dehydrogenase [ubiquinone] iron-sulfur protein 2, mitochondrial OS=Homo sapiens OX=9606 GN=NDUFS2 PE=1 SV=2" 6.61 2791.6 - 2.55E+06 - - - -2.4733 - 2.411 0.544 - 364.4 1 2 0 -0.0033 11 0 0 0 5.35E+07 5.69E+07 - - - 7.1042 0.9995 221125_WJC_METTL3_EV_vs_WT_F06.16901.16901.3 3.61E-06 16/60 R.KFNALFAQGNYSEAAK.V "sp|Q00610|CLH1_HUMAN,tr|A0A087WVQ6|A0A087WVQ6_HUMAN" 2 1757.8737 1.23 85364 16901 3 1757.866049 586.9652 Clathrin heavy chain 1 OS=Homo sapiens OX=9606 GN=CLTC PE=1 SV=5 8.5 2791.8 - 1.75E+06 - - - -4.3433 - 2.7 0.44 - 424.5 1 2 0 -0.0076 16 0 0 0 2.53E+07 2.06E+07 - - - 5.992 0.9973 221125_WJC_METTL3_EV_vs_WT_F06.16904.16904.3 1.34E-05 21/68 V.IHLSNLPHSGYSDSAVLK.L "sp|P43243|MATR3_HUMAN,tr|B3KM87|B3KM87_HUMAN,tr|A8MXP9|A8MXP9_HUMAN,tr|D6RBK5|D6RBK5_HUMAN,tr|A0A0R4J2E8|A0A0R4J2E8_HUMAN,tr|H0Y8T4|H0Y8T4_HUMAN,tr|D6REM6|D6REM6_HUMAN" 7 1937.0007 1.98 85365 16904 3 1936.999206 646.6742 Matrin-3 OS=Homo sapiens OX=9606 GN=MATR3 PE=1 SV=2 6.92 2792.1 - 1.99E+06 - - - -0.7589 - 3.229 0.469 - 314.6 1 1 0 -0.0015 18 0 0 0 5.76E+07 2.90E+07 - - - 6.6873 1 221125_WJC_METTL3_EV_vs_WT_F06.16906.16906.3 2.03E-15 20/96 K.LVQDVANNTNEEAGDGTTTATVLAR.S "sp|P10809|CH60_HUMAN,tr|C9JL25|C9JL25_HUMAN,tr|A0A7I2V2X6|A0A7I2V2X6_HUMAN,tr|A0A7I2YQK6|A0A7I2YQK6_HUMAN,tr|A0A7I2V599|A0A7I2V599_HUMAN,tr|E7EXB4|E7EXB4_HUMAN,tr|A0A7I2YQ71|A0A7I2YQ71_HUMAN,tr|E7ESH4|E7ESH4_HUMAN,tr|A0A7I2V5M1|A0A7I2V5M1_HUMAN,tr|A0A7I2V5K3|A0A7I2V5K3_HUMAN,tr|A0A7I2V369|A0A7I2V369_HUMAN" 11 2559.2413 1.45 85366 16906 3 2559.239264 854.0877 "60 kDa heat shock protein, mitochondrial OS=Homo sapiens OX=9606 GN=HSPD1 PE=1 SV=2" 3.92 2792.4 - 2.36E+07 - - - -0.7772 - 3.809 0.691 - 440 1 2 0 -0.002 25 0 0 0 2.31E+09 1.59E+09 - - - 9.3202 1 221125_WJC_METTL3_EV_vs_WT_F06.16908.16908.3 4.34E-05 14/52 K.LTFDTTFSPNTGKK.S "sp|P45880|VDAC2_HUMAN,tr|Q5JSD1|Q5JSD1_HUMAN,tr|Q5JSD2|Q5JSD2_HUMAN,tr|A0A0A0MR02|A0A0A0MR02_HUMAN" 4 1555.7882 1.2 85368 16908 3 1555.785589 519.6034 Voltage-dependent anion-selective channel protein 2 OS=Homo sapiens OX=9606 GN=VDAC2 PE=1 SV=2 8.59 2792.5 - 8.39E+06 - - - -1.693 - 2.57 0.558 - 221.1 1 2 0 -0.0026 14 0 0 0 2.75E+08 2.30E+08 - - - 7.2689 0.9998 221125_WJC_METTL3_EV_vs_WT_F06.16914.16914.4 2.63E-07 19/66 K.LKDYAFVHFEDR.G "sp|O43390|HNRPR_HUMAN,tr|B4DT28|B4DT28_HUMAN,tr|A0A6Q8PH31|A0A6Q8PH31_HUMAN,tr|A0A6Q8PH35|A0A6Q8PH35_HUMAN" 4 1538.7518 1.49 85372 16914 4 1538.748832 385.6952 Heterogeneous nuclear ribonucleoprotein R OS=Homo sapiens OX=9606 GN=HNRNPR PE=1 SV=1 5.38 2793.2 - 1.54E+06 - - - -1.9145 - 2.992 0.496 - 408.6 1 2 1 -0.0029 12 0 0 0 3.79E+07 2.54E+07 - - - 3.9571 1 221125_WJC_METTL3_EV_vs_WT_F06.16915.16915.3 1.55E-09 23/68 R.AC[160.03]YLSINPQK[136.11]DETLETEK[136.11].A "sp|P61163|ACTZ_HUMAN,tr|R4GMT0|R4GMT0_HUMAN" 2 2154.0486 1.49 85373 16915 3 2154.045022 719.0235 Alpha-centractin OS=Homo sapiens OX=9606 GN=ACTR1A PE=1 SV=1 4.41 2793.4 - 1.47E+06 - - - -1.6383 - 3.269 0.64 - 277.7 1 2 1 -0.0035 18 0 0 0 4.49E+07 3.01E+07 - - - 8.6239 1 221125_WJC_METTL3_EV_vs_WT_F06.16918.16918.3 1.38E-14 22/96 K.LVQDVANNTNEEAGDGTTTATVLAR[166.11].S "sp|P10809|CH60_HUMAN,tr|C9JL25|C9JL25_HUMAN,tr|A0A7I2V2X6|A0A7I2V2X6_HUMAN,tr|A0A7I2YQK6|A0A7I2YQK6_HUMAN,tr|A0A7I2V599|A0A7I2V599_HUMAN,tr|E7EXB4|E7EXB4_HUMAN,tr|A0A7I2YQ71|A0A7I2YQ71_HUMAN,tr|E7ESH4|E7ESH4_HUMAN,tr|A0A7I2V5M1|A0A7I2V5M1_HUMAN,tr|A0A7I2V5K3|A0A7I2V5K3_HUMAN,tr|A0A7I2V369|A0A7I2V369_HUMAN" 11 2569.2495 1.5 85374 16918 3 2569.245457 857.4238 "60 kDa heat shock protein, mitochondrial OS=Homo sapiens OX=9606 GN=HSPD1 PE=1 SV=2" 3.92 2793.8 - 1.26E+07 - - - -1.5826 - 4.168 0.708 - 707.8 1 2 0 -0.0041 25 0 0 0 2.66E+09 1.77E+09 - - - 9.7164 1 221125_WJC_METTL3_EV_vs_WT_F06.16919.16919.3 2.94E-06 23/68 K.AGAKPDQIGIITPYEGQR.S sp|Q92900|RENT1_HUMAN 1 1913.0007 1.17 85375 16919 3 1912.997675 638.6742 Regulator of nonsense transcripts 1 OS=Homo sapiens OX=9606 GN=UPF1 PE=1 SV=2 6.11 2793.8 - 8.58E+06 - - - -1.5687 - 4.086 0.602 - 621.1 1 2 0 -0.003 18 0 0 0 2.27E+08 1.94E+08 - - - 8.7559 0.999 221125_WJC_METTL3_EV_vs_WT_F06.16921.16921.4 0.00018 18/66 K.LK[136.11]DYAFVHFEDR[166.11].G "sp|O43390|HNRPR_HUMAN,tr|B4DT28|B4DT28_HUMAN,tr|A0A6Q8PH31|A0A6Q8PH31_HUMAN,tr|A0A6Q8PH35|A0A6Q8PH35_HUMAN" 4 1556.7742 1.44 85377 16921 4 1556.773046 390.2008 Heterogeneous nuclear ribonucleoprotein R OS=Homo sapiens OX=9606 GN=HNRNPR PE=1 SV=1 5.38 2794 - 1.64E+06 - - - -0.7721 - 2.639 0.356 - 296.8 1 2 1 -0.0012 12 0 0 0 3.79E+07 2.62E+07 - - - 2.6915 0.9979 221125_WJC_METTL3_EV_vs_WT_F06.16927.16927.3 0.00562 Dec-44 K.NKLEGLEDALQK.A "sp|P48668|K2C6C_HUMAN,sp|P04259|K2C6B_HUMAN,sp|P02538|K2C6A_HUMAN" 3 1356.7249 999 85380 16927 3 1356.724309 453.2489 "Keratin, type II cytoskeletal 6C OS=Homo sapiens OX=9606 GN=KRT6C PE=1 SV=3" 4.68 2794.7 - 2.62E+06 - - - -0.4319 - 2.326 0.269 - 349.3 1 2 1 -0.0006 12 0 0 0 1.02E+09 0.00E+00 - - - 3.8788 0.9998 221125_WJC_METTL3_EV_vs_WT_F06.16928.16928.3 2.30E-06 16/56 K.DVDAAYMNKVELQAK.A "sp|P48668|K2C6C_HUMAN,sp|P04259|K2C6B_HUMAN,sp|Q14CN4|K2C72_HUMAN,sp|P02538|K2C6A_HUMAN" 4 1693.8345 9.51 85381 16928 3 1693.833085 565.6188 "Keratin, type II cytoskeletal 6C OS=Homo sapiens OX=9606 GN=KRT6C PE=1 SV=3" 4.56 2794.9 - 1.65E+06 - - - -0.8484 - 2.369 0.477 - 181.9 1 2 1 -0.0014 15 0 0 0 3.71E+07 3.90E+06 - - - 6.1082 0.9999 221125_WJC_METTL3_EV_vs_WT_F06.16933.16933.3 6.15E-08 13/52 K.C[160.03]THSSSIEDLALGR.C sp|Q9NS00|C1GLT_HUMAN 1 1544.7253 1.28 85384 16933 3 1544.721383 515.9157 Glycoprotein-N-acetylgalactosamine 3-beta-galactosyltransferase 1 OS=Homo sapiens OX=9606 GN=C1GALT1 PE=1 SV=1 5.32 2795.5 - 3.48E+06 - - - -2.5396 - 2.575 0.437 - 241.3 1 2 0 -0.0039 14 0 0 0 7.33E+07 5.74E+07 - - - 5.9247 1 221125_WJC_METTL3_EV_vs_WT_F06.16936.16936.3 3.60E-10 19/64 R.K[136.11]DLLVENVPYC[160.03]DAPTQK[136.11].Q "sp|Q5U5X0|LYRM7_HUMAN,tr|D6R994|D6R994_HUMAN" 2 2005.0161 1.17 85387 16936 3 2005.014204 669.346 Complex III assembly factor LYRM7 OS=Homo sapiens OX=9606 GN=LYRM7 PE=1 SV=1 4.56 2795.8 - 2.21E+06 - - - -0.9596 - 3.256 0.616 - 577.9 1 2 0 -0.0019 17 0 0 0 9.47E+07 8.06E+07 - - - 8.3896 0.9999 221125_WJC_METTL3_EV_vs_WT_F06.16937.16937.4 9.87E-09 19/90 K.LRETLEEYNKEFAEVK.N "sp|Q13948|CASP_HUMAN,sp|P39880|CUX1_HUMAN,tr|A0A2R8Y852|A0A2R8Y852_HUMAN,tr|A0A2R8YDI1|A0A2R8YDI1_HUMAN" 4 1997.0106 1.03 85388 16937 4 1997.007468 500.2599 Protein CASP OS=Homo sapiens OX=9606 GN=CUX1 PE=1 SV=2 4.65 2795.9 - 1.72E+06 - - - -1.5543 - 2.921 0.561 - 332.7 1 2 2 -0.0031 16 0 0 0 1.09E+08 1.06E+08 - - - 4.4857 0.9999 221125_WJC_METTL3_EV_vs_WT_F06.16938.16938.3 5.55E-06 15/40 R.RAPFDLFENKK.K "sp|P08238|HS90B_HUMAN,sp|Q58FF7|H90B3_HUMAN" 2 1363.7248 0.69 85389 16938 3 1363.722575 455.5822 Heat shock protein HSP 90-beta OS=Homo sapiens OX=9606 GN=HSP90AB1 PE=1 SV=4 8.59 2796 - 659237 - - - -1.6572 - 2.624 0.365 - 279 1 2 0 -0.0023 11 0 0 0 2.35E+07 3.41E+07 - - - 5.3493 1 221125_WJC_METTL3_EV_vs_WT_F06.16942.16942.3 7.84E-10 29/60 K.LRETLEEYNKEFAEVK.N "sp|Q13948|CASP_HUMAN,sp|P39880|CUX1_HUMAN,tr|A0A2R8Y852|A0A2R8Y852_HUMAN,tr|A0A2R8YDI1|A0A2R8YDI1_HUMAN" 4 1997.0106 1.76 85391 16942 3 1997.01047 666.6775 Protein CASP OS=Homo sapiens OX=9606 GN=CUX1 PE=1 SV=2 4.65 2796.5 - 2.04E+06 - - - -0.0511 - 4.821 0.635 - 1687 1 2 2 -0.0001 16 0 0 0 1.06E+08 6.04E+07 - - - 9.6557 1 221125_WJC_METTL3_EV_vs_WT_F06.16943.16943.3 3.06E-08 18/64 R.KDLLVENVPYC[160.03]DAPTQK.Q "sp|Q5U5X0|LYRM7_HUMAN,tr|D6R994|D6R994_HUMAN" 2 1988.9877 1.17 85392 16943 3 1988.989546 664.0032 Complex III assembly factor LYRM7 OS=Homo sapiens OX=9606 GN=LYRM7 PE=1 SV=1 4.56 2796.6 - 3.34E+06 - - - 0.914 - 3.064 0.588 - 530.9 1 2 0 0.0018 17 0 0 0 9.47E+07 8.06E+07 - - - 7.9239 1 221125_WJC_METTL3_EV_vs_WT_F06.16945.16945.2 2.35E-09 Dec-32 R.WNSPAEEGSSDC[160.03]EVFSK[136.11].N "sp|P34932|HSP74_HUMAN,tr|A0A087WTS8|A0A087WTS8_HUMAN,tr|A0A087WYC1|A0A087WYC1_HUMAN" 3 1935.8036 0.001 85394 16945 2 1935.803499 968.9091 Heat shock 70 kDa protein 4 OS=Homo sapiens OX=9606 GN=HSPA4 PE=1 SV=4 4 2796.9 - 1.24E+06 - - - -0.0635 - 2.838 0.669 - 415.4 1 2 0 -0.0001 17 0 0 0 0.00E+00 5.27E+07 - - - 6.5467 0.9996 221125_WJC_METTL3_EV_vs_WT_F06.16947.16947.3 4.01E-09 15/40 R.R[166.11]APFDLFENK[136.11]K[136.11].K "sp|P08238|HS90B_HUMAN,sp|Q58FF7|H90B3_HUMAN" 2 1389.7615 0.75 85396 16947 3 1389.755445 464.2611 Heat shock protein HSP 90-beta OS=Homo sapiens OX=9606 GN=HSP90AB1 PE=1 SV=4 8.59 2797.1 - 1.08E+06 - - - -4.3605 - 2.651 0.447 - 319.2 1 2 0 -0.0061 11 0 0 0 2.35E+07 3.13E+07 - - - 6.2916 1 221125_WJC_METTL3_EV_vs_WT_F06.16953.16953.3 2.14E-12 24/60 K.LR[166.11]ETLEEYNK[136.11]EFAEVK[136.11].N "sp|Q13948|CASP_HUMAN,sp|P39880|CUX1_HUMAN,tr|A0A2R8Y852|A0A2R8Y852_HUMAN,tr|A0A2R8YDI1|A0A2R8YDI1_HUMAN" 4 2023.0472 1.76 85400 16953 3 2023.047831 675.3564 Protein CASP OS=Homo sapiens OX=9606 GN=CUX1 PE=1 SV=2 4.65 2797.7 - 2.50E+06 - - - 0.2911 - 4.084 0.65 - 863.8 1 2 2 0.0006 16 0 0 0 1.06E+08 6.04E+07 - - - 9.3971 1 221125_WJC_METTL3_EV_vs_WT_F06.16963.16963.2 3.42E-13 18/36 R.GLLQDDAHPTLVTYADHSK[136.11].L "sp|Q86U44|MTA70_HUMAN,tr|F5H6D8|F5H6D8_HUMAN,tr|H0YFV6|H0YFV6_HUMAN,tr|B4DTN4|B4DTN4_HUMAN" 4 2088.0367 0.001 85409 16963 2 2088.028842 1045.0256 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 5.13 2798.9 - 682252 - - - -3.7791 - 3.405 0.714 - 729.9 1 2 0 -0.0079 19 0 0 0 0.00E+00 1.97E+08 - - - 7.3244 0.9999 221125_WJC_METTL3_EV_vs_WT_F06.16965.16965.4 1.19E-06 18/90 K.LR[166.11]ETLEEYNK[136.11]EFAEVK[136.11].N "sp|Q13948|CASP_HUMAN,sp|P39880|CUX1_HUMAN,tr|A0A2R8Y852|A0A2R8Y852_HUMAN,tr|A0A2R8YDI1|A0A2R8YDI1_HUMAN" 4 2023.0472 1.47 85411 16965 4 2023.049717 506.7691 Protein CASP OS=Homo sapiens OX=9606 GN=CUX1 PE=1 SV=2 4.65 2799 - 3.82E+06 - - - 1.2234 - 3.35 0.574 - 291.8 1 2 2 0.0025 16 0 0 0 7.79E+07 5.32E+07 - - - 4.6473 1 221125_WJC_METTL3_EV_vs_WT_F06.16968.16968.2 1.20E-16 23/48 K.LVQDVANNTNEEAGDGTTTATVLAR.S "sp|P10809|CH60_HUMAN,tr|C9JL25|C9JL25_HUMAN,tr|A0A7I2V2X6|A0A7I2V2X6_HUMAN,tr|A0A7I2YQK6|A0A7I2YQK6_HUMAN,tr|A0A7I2V599|A0A7I2V599_HUMAN,tr|E7EXB4|E7EXB4_HUMAN,tr|A0A7I2YQ71|A0A7I2YQ71_HUMAN,tr|E7ESH4|E7ESH4_HUMAN,tr|A0A7I2V5M1|A0A7I2V5M1_HUMAN,tr|A0A7I2V5K3|A0A7I2V5K3_HUMAN,tr|A0A7I2V369|A0A7I2V369_HUMAN" 11 2559.2413 1.45 85414 16968 2 2559.236412 1280.6279 "60 kDa heat shock protein, mitochondrial OS=Homo sapiens OX=9606 GN=HSPD1 PE=1 SV=2" 3.92 2799.3 - 903950 - - - -1.8916 - 4.515 0.767 - 1398.1 1 2 0 -0.0048 25 0 0 0 4.39E+07 3.04E+07 - - - 8.4106 0.9999 221125_WJC_METTL3_EV_vs_WT_F06.16971.16971.3 3.85E-06 18/64 R.FSREEFPTLQAAGDQDK.A sp|P48634|PRC2A_HUMAN 1 1937.9119 1.53 85415 16971 3 1937.910821 646.9779 Protein PRRC2A OS=Homo sapiens OX=9606 GN=PRRC2A PE=1 SV=3 4.32 2799.7 - 4.20E+06 - - - -0.5671 - 3.327 0.532 - 433.8 1 2 1 -0.0011 17 0 0 0 1.14E+08 7.41E+07 - - - 7.5078 1 221125_WJC_METTL3_EV_vs_WT_F06.16978.16978.2 3.26E-10 17/34 K.GTQTYSVLEGDPSENYSK[136.11].Y "sp|P52701|MSH6_HUMAN,tr|A0A494C0M1|A0A494C0M1_HUMAN,tr|A0A087WWJ1|A0A087WWJ1_HUMAN" 3 1981.8996 0.34 85422 16978 2 1981.895777 991.9571 DNA mismatch repair protein Msh6 OS=Homo sapiens OX=9606 GN=MSH6 PE=1 SV=2 4.14 2800.3 - 963691 - - - -1.9446 - 3.272 0.711 - 602.4 1 2 0 -0.0039 18 0 0 0 3.04E+06 8.96E+06 - - - 7.2056 0.9987 221125_WJC_METTL3_EV_vs_WT_F06.16986.16986.3 5.85E-05 15/80 K.GALDTTDGYMGVNQAPEKLDK.Q "sp|Q9UPN3|MACF1_HUMAN,tr|H3BQK9|H3BQK9_HUMAN,tr|A0A7P0MQR8|A0A7P0MQR8_HUMAN,tr|E9PNZ4|E9PNZ4_HUMAN,tr|H0Y390|H0Y390_HUMAN,tr|H3BPE1|H3BPE1_HUMAN,tr|A0A590UJG2|A0A590UJG2_HUMAN" 7 2222.0525 999 85428 16986 3 2222.052464 741.6914 "Microtubule-actin cross-linking factor 1, isoforms 1\2\3\5 OS=Homo sapiens OX=9606 GN=MACF1 PE=1 SV=4" 4.23 2801.3 - 1.08E+06 - - - -0.0221 - 2.657 0.303 - 148.2 1 2 1 0 21 0 0 0 9.64E+06 0.00E+00 - - - 4.2609 0.9997 221125_WJC_METTL3_EV_vs_WT_F06.16987.16987.3 3.07E-05 14/56 R.KFDFDAC[160.03]NEVPPAPK.E "sp|Q14151|SAFB2_HUMAN,sp|Q15424|SAFB1_HUMAN" 2 1733.8083 3.71 85429 16987 3 1733.802591 578.9434 Scaffold attachment factor B2 OS=Homo sapiens OX=9606 GN=SAFB2 PE=1 SV=1 4.56 2801.4 - 882681 - - - -3.2968 - 2.366 0.446 - 210.9 1 2 0 -0.0057 15 0 0 0 2.16E+07 5.84E+06 - - - 5.7581 0.9982 221125_WJC_METTL3_EV_vs_WT_F06.17013.17013.2 5.14E-05 16/22 K.NKLEGLEDALQK.A "sp|P48668|K2C6C_HUMAN,sp|P04259|K2C6B_HUMAN,sp|P02538|K2C6A_HUMAN" 3 1356.7249 999 85442 17013 2 1356.724202 679.3697 "Keratin, type II cytoskeletal 6C OS=Homo sapiens OX=9606 GN=KRT6C PE=1 SV=3" 4.68 2804.4 - 1.60E+07 - - - -0.5108 - 2.904 0.349 - 951.4 1 2 1 -0.0007 12 0 0 0 6.77E+08 0.00E+00 - - - 4.4236 1 221125_WJC_METTL3_EV_vs_WT_F06.17053.17053.4 1.74E-09 30/96 R.VK[136.11]PAPDETSFSEALLK[136.11]R[166.11].N "sp|Q12905|ILF2_HUMAN,tr|B4DY09|B4DY09_HUMAN,tr|X6R6Z1|X6R6Z1_HUMAN,tr|A0A0A0MRL0|A0A0A0MRL0_HUMAN" 4 1913.0468 1.21 85453 17053 4 1913.040219 479.269 Interleukin enhancer-binding factor 2 OS=Homo sapiens OX=9606 GN=ILF2 PE=1 SV=2 6.15 2809.8 - 3.37E+06 - - - -3.4652 - 3.731 0.663 - 639.1 1 2 0 -0.0066 17 0 0 0 4.20E+08 3.47E+08 - - - 5.4521 1 221125_WJC_METTL3_EV_vs_WT_F06.17066.17066.4 9.58E-09 23/96 R.VKPAPDETSFSEALLKR.N "sp|Q12905|ILF2_HUMAN,tr|B4DY09|B4DY09_HUMAN,tr|X6R6Z1|X6R6Z1_HUMAN,tr|A0A0A0MRL0|A0A0A0MRL0_HUMAN" 4 1887.0102 1.21 85455 17066 4 1887.004456 472.7598 Interleukin enhancer-binding factor 2 OS=Homo sapiens OX=9606 GN=ILF2 PE=1 SV=2 6.15 2811.8 - 6.30E+06 - - - -3.0323 - 3.735 0.618 - 519.5 1 2 0 -0.0057 17 0 0 0 4.21E+08 3.48E+08 - - - 5.061 1 221125_WJC_METTL3_EV_vs_WT_F06.17069.17069.2 1.85E-10 18/26 K.SGKWEGLVYAPPGK.E "sp|Q9Y2W1|TR150_HUMAN,tr|A0A3B3ITZ9|A0A3B3ITZ9_HUMAN" 2 1487.7773 3.05 85456 17069 2 1487.779714 744.8959 Thyroid hormone receptor-associated protein 3 OS=Homo sapiens OX=9606 GN=THRAP3 PE=1 SV=2 8.22 2812.2 - 3.36E+06 - - - 1.6461 - 3.331 0.653 - 723.7 1 2 1 0.0024 14 0 0 0 4.23E+08 1.39E+08 - - - 6.8828 0.9998 221125_WJC_METTL3_EV_vs_WT_F06.17072.17072.3 3.66E-05 15/52 K.SGKWEGLVYAPPGK.E "sp|Q9Y2W1|TR150_HUMAN,tr|A0A3B3ITZ9|A0A3B3ITZ9_HUMAN" 2 1487.7773 2.57 85457 17072 3 1487.774933 496.933 Thyroid hormone receptor-associated protein 3 OS=Homo sapiens OX=9606 GN=THRAP3 PE=1 SV=2 8.22 2812.6 - 2.05E+07 - - - -1.5674 - 2.816 0.489 - 228.7 1 2 1 -0.0023 14 0 0 0 1.89E+09 7.34E+08 - - - 6.7426 1 221125_WJC_METTL3_EV_vs_WT_F06.17078.17078.2 1.12E-15 24/48 K.LVQDVANNTNEEAGDGTTTATVLAR[166.11].S "sp|P10809|CH60_HUMAN,tr|C9JL25|C9JL25_HUMAN,tr|A0A7I2V2X6|A0A7I2V2X6_HUMAN,tr|A0A7I2YQK6|A0A7I2YQK6_HUMAN,tr|A0A7I2V599|A0A7I2V599_HUMAN,tr|E7EXB4|E7EXB4_HUMAN,tr|A0A7I2YQ71|A0A7I2YQ71_HUMAN,tr|E7ESH4|E7ESH4_HUMAN,tr|A0A7I2V5M1|A0A7I2V5M1_HUMAN,tr|A0A7I2V5K3|A0A7I2V5K3_HUMAN,tr|A0A7I2V369|A0A7I2V369_HUMAN" 11 2569.2495 0.91 85458 17078 2 2570.237889 1285.632 "60 kDa heat shock protein, mitochondrial OS=Homo sapiens OX=9606 GN=HSPD1 PE=1 SV=2" 3.92 2813.5 - 6.79E+06 - - - 384.6905 - 4.487 0.695 - 1726.9 1 2 0 0.9884 25 0 0 0 1.75E+07 1.93E+07 - - - 7.5547 1 221125_WJC_METTL3_EV_vs_WT_F06.17084.17084.3 1.40E-14 24/64 R.VK[136.11]PAPDETSFSEALLK[136.11]R[166.11].N "sp|Q12905|ILF2_HUMAN,tr|B4DY09|B4DY09_HUMAN,tr|X6R6Z1|X6R6Z1_HUMAN,tr|A0A0A0MRL0|A0A0A0MRL0_HUMAN" 4 1913.0468 1.82 85460 17084 3 1913.043686 638.6896 Interleukin enhancer-binding factor 2 OS=Homo sapiens OX=9606 GN=ILF2 PE=1 SV=2 6.15 2814.3 - 2.28E+06 - - - -1.6529 - 4.237 0.703 - 490.9 1 2 0 -0.0032 17 0 0 0 3.69E+08 2.02E+08 - - - 10.0245 1 221125_WJC_METTL3_EV_vs_WT_F06.17090.17090.3 4.11E-12 16/72 R.GLLQDDAHPTLVTYADHSK[136.11].L "sp|Q86U44|MTA70_HUMAN,tr|F5H6D8|F5H6D8_HUMAN,tr|H0YFV6|H0YFV6_HUMAN,tr|B4DTN4|B4DTN4_HUMAN" 4 2088.0367 0 85461 17090 3 2088.032382 697.0195 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 5.13 2815.2 - 1.39E+07 - - - -2.0838 - 3.245 0.632 - 285.3 1 2 0 -0.0044 19 0 0 0 1.04E+06 1.24E+09 - - - 8.4769 1 221125_WJC_METTL3_EV_vs_WT_F06.17097.17097.2 1.99E-11 19/26 K.SGK[136.11]WEGLVYAPPGK[136.11].E "sp|Q9Y2W1|TR150_HUMAN,tr|A0A3B3ITZ9|A0A3B3ITZ9_HUMAN" 2 1503.8057 3.04 85463 17097 2 1503.802229 752.9101 Thyroid hormone receptor-associated protein 3 OS=Homo sapiens OX=9606 GN=THRAP3 PE=1 SV=2 8.22 2816.1 - 4.25E+06 - - - -2.2849 - 3.781 0.619 - 856.1 1 2 1 -0.0034 14 0 0 0 4.21E+08 1.39E+08 - - - 6.9494 1 221125_WJC_METTL3_EV_vs_WT_F06.17104.17104.3 4.66E-07 14/72 K.VQASLAANTFTITGHAETK[136.11].Q "sp|P20290|BTF3_HUMAN,tr|A0A7I2V3T6|A0A7I2V3T6_HUMAN,tr|D6RDG3|D6RDG3_HUMAN,tr|A0A7I2V5Y3|A0A7I2V5Y3_HUMAN,tr|H0Y9Y1|H0Y9Y1_HUMAN,tr|A0A7I2YQL2|A0A7I2YQL2_HUMAN" 6 1967.0204 0.95 85466 17104 3 1967.018674 656.6807 Transcription factor BTF3 OS=Homo sapiens OX=9606 GN=BTF3 PE=1 SV=1 6.72 2817 - 6.01E+06 - - - -0.8546 - 3.139 0.584 - 230.3 1 2 0 -0.0017 19 0 0 0 4.29E+08 4.51E+08 - - - 7.8609 0.9998 221125_WJC_METTL3_EV_vs_WT_F06.17105.17105.3 3.66E-07 23/76 K.AMEVDER[166.11]PTEQYSDIGGLDK[136.11].Q "sp|P17980|PRS6A_HUMAN,tr|R4GNH3|R4GNH3_HUMAN,tr|E9PMD8|E9PMD8_HUMAN,tr|E9PM69|E9PM69_HUMAN,tr|E9PN50|E9PN50_HUMAN" 5 2270.0492 0.77 85467 17105 3 2270.037745 757.6903 26S proteasome regulatory subunit 6A OS=Homo sapiens OX=9606 GN=PSMC3 PE=1 SV=3 4.02 2817.1 - 4.27E+06 - - - -5.0294 - 3.366 0.592 - 549.1 1 2 0 -0.0114 20 0 0 0 5.84E+07 7.62E+07 - - - 8.0816 0.9997 221125_WJC_METTL3_EV_vs_WT_F06.17106.17106.3 0.0021 25/52 R.FKVEESYDLKDTLR.T sp|P29508|SPB3_HUMAN 1 1741.8887 5.37 85468 17106 3 1741.882802 581.6368 Serpin B3 OS=Homo sapiens OX=9606 GN=SERPINB3 PE=1 SV=2 4.78 2817.2 - 1.80E+06 - - - -3.3665 - 4.587 0.488 - 762.5 1 2 2 -0.0059 14 0 0 0 9.04E+07 1.69E+07 - - - 8.0271 1 221125_WJC_METTL3_EV_vs_WT_F06.17109.17109.2 5.76E-08 19/28 R.QDIQTDNSDIFQETK.V "sp|Q15643|TRIPB_HUMAN,tr|H0YJ97|H0YJ97_HUMAN" 2 1780.8115 1.17 85469 17109 2 1780.81016 891.413 Thyroid receptor-interacting protein 11 OS=Homo sapiens OX=9606 GN=TRIP11 PE=1 SV=3 3.84 2817.6 - 5.30E+06 - - - -0.7738 - 3.706 0.643 - 1292.2 1 2 0 -0.0014 15 0 0 0 3.97E+08 3.39E+08 - - - 7.0103 1 221125_WJC_METTL3_EV_vs_WT_F06.17111.17111.3 3.34E-06 18/72 K.VQASLAANTFTITGHAETK.Q "sp|P20290|BTF3_HUMAN,tr|A0A7I2V3T6|A0A7I2V3T6_HUMAN,tr|D6RDG3|D6RDG3_HUMAN,tr|A0A7I2V5Y3|A0A7I2V5Y3_HUMAN,tr|H0Y9Y1|H0Y9Y1_HUMAN,tr|A0A7I2YQL2|A0A7I2YQL2_HUMAN" 6 1959.0062 0.95 85471 17111 3 1959.006032 654.0093 Transcription factor BTF3 OS=Homo sapiens OX=9606 GN=BTF3 PE=1 SV=1 6.72 2817.8 - 8.64E+06 - - - -0.0628 - 3.221 0.51 - 338 1 2 0 -0.0001 19 0 0 0 4.35E+08 4.60E+08 - - - 7.0997 1 221125_WJC_METTL3_EV_vs_WT_F06.17114.17114.2 2.32E-08 17/28 R.QDIQTDNSDIFQETK[136.11].V "sp|Q15643|TRIPB_HUMAN,tr|H0YJ97|H0YJ97_HUMAN" 2 1788.8257 1.17 85472 17114 2 1788.8261 895.4201 Thyroid receptor-interacting protein 11 OS=Homo sapiens OX=9606 GN=TRIP11 PE=1 SV=3 3.84 2818.2 - 8.54E+06 - - - 0.2024 - 3.35 0.651 - 1081.8 1 2 0 0.0004 15 0 0 0 3.97E+08 3.39E+08 - - - 6.8215 1 221125_WJC_METTL3_EV_vs_WT_F06.17117.17117.3 2.32E-08 18/56 R.QDIQTDNSDIFQETK.V "sp|Q15643|TRIPB_HUMAN,tr|H0YJ97|H0YJ97_HUMAN" 2 1780.8115 1.02 85473 17117 3 1780.80911 594.6111 Thyroid receptor-interacting protein 11 OS=Homo sapiens OX=9606 GN=TRIP11 PE=1 SV=3 3.84 2818.6 - 4.04E+06 - - - -1.3634 - 2.882 0.548 - 486.4 1 2 0 -0.0024 15 0 0 0 1.07E+08 1.05E+08 - - - 7.411 0.9999 221125_WJC_METTL3_EV_vs_WT_F06.17118.17118.4 6.42E-08 19/78 R.FKVEESYDLKDTLR.T sp|P29508|SPB3_HUMAN 1 1741.8887 999 85474 17118 4 1741.888627 436.4794 Serpin B3 OS=Homo sapiens OX=9606 GN=SERPINB3 PE=1 SV=2 4.78 2818.7 - 2.52E+06 - - - -0.0224 - 3.4 0.519 - 269.9 1 2 2 0 14 0 0 0 6.51E+07 0.00E+00 - - - 4.1888 1 221125_WJC_METTL3_EV_vs_WT_F06.17119.17119.3 1.41E-07 15/52 R.KLC[160.03]LNIC[160.03]VGESGDR.L "sp|P62913|RL11_HUMAN,tr|Q5VVC8|Q5VVC8_HUMAN" 2 1619.776 1.31 85475 17119 3 1619.77763 540.9326 60S ribosomal protein L11 OS=Homo sapiens OX=9606 GN=RPL11 PE=1 SV=2 6.06 2818.8 - 5.56E+06 - - - 1.0304 - 2.928 0.556 - 323.2 1 2 0 0.0017 14 0 0 0 1.41E+08 1.07E+08 - - - 7.5934 1 221125_WJC_METTL3_EV_vs_WT_F06.17120.17120.3 9.51E-09 19/76 K.AMEVDERPTEQYSDIGGLDK.Q "sp|P17980|PRS6A_HUMAN,tr|R4GNH3|R4GNH3_HUMAN,tr|E9PMD8|E9PMD8_HUMAN,tr|E9PM69|E9PM69_HUMAN,tr|E9PN50|E9PN50_HUMAN" 5 2252.0267 0.77 85476 17120 3 2252.028968 751.6828 26S proteasome regulatory subunit 6A OS=Homo sapiens OX=9606 GN=PSMC3 PE=1 SV=3 4.02 2818.9 - 3.83E+06 - - - 1.0106 - 3.336 0.611 - 426.7 1 2 0 0.0023 20 0 0 0 5.84E+07 7.62E+07 - - - 8.2742 0.9996 221125_WJC_METTL3_EV_vs_WT_F06.17125.17125.3 6.21E-06 16/44 R.TVITEEFKVPDK.M sp|Q96I24|FUBP3_HUMAN 1 1404.75 1.75 85479 17125 3 1404.748539 469.2573 Far upstream element-binding protein 3 OS=Homo sapiens OX=9606 GN=FUBP3 PE=1 SV=2 4.68 2819.4 - 3.06E+06 - - - -1.0735 - 2.523 0.374 - 256.4 1 2 1 -0.0015 12 0 0 0 9.95E+07 5.69E+07 - - - 5.2745 1 221125_WJC_METTL3_EV_vs_WT_F06.17126.17126.2 2.27E-12 21/40 R.AAASSYNTQGAASSLGSYGAQ.A sp|Q96PK6|RBM14_HUMAN 1 1960.8763 - 85480 17126 2 1960.878043 981.4454 RNA-binding protein 14 OS=Homo sapiens OX=9606 GN=RBM14 PE=1 SV=2 5.57 2819.6 - 2.51E+06 - - - 0.9078 - 4.151 0.683 - 752.9 1 1 0 0.0018 21 0 0 0 - - - - - 7.5844 1 221125_WJC_METTL3_EV_vs_WT_F06.17131.17131.3 8.67E-08 17/56 R.QDIQTDNSDIFQETK[136.11].V "sp|Q15643|TRIPB_HUMAN,tr|H0YJ97|H0YJ97_HUMAN" 2 1788.8257 0.98 85483 17131 3 1788.825413 597.2825 Thyroid receptor-interacting protein 11 OS=Homo sapiens OX=9606 GN=TRIP11 PE=1 SV=3 3.84 2820.2 - 5.11E+06 - - - -0.1817 - 3.28 0.545 - 444.4 1 2 0 -0.0003 15 0 0 0 1.12E+08 1.15E+08 - - - 7.7156 1 221125_WJC_METTL3_EV_vs_WT_F06.17133.17133.4 1.02E-06 13/108 R.GLLQDDAHPTLVTYADHSK[136.11].L "sp|Q86U44|MTA70_HUMAN,tr|F5H6D8|F5H6D8_HUMAN,tr|H0YFV6|H0YFV6_HUMAN,tr|B4DTN4|B4DTN4_HUMAN" 4 2088.0367 0.01 85485 17133 4 2088.033354 523.0165 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 5.13 2820.4 - 4.38E+07 - - - -1.6183 - 2.572 0.602 - 158.2 1 2 0 -0.0034 19 0 0 0 2.45E+07 2.08E+09 - - - 4.7844 0.9999 221125_WJC_METTL3_EV_vs_WT_F06.17135.17135.4 1.67E-06 17/78 K.DVVVQHVHFDGLGR.T sp|Q9Y512|SAM50_HUMAN 1 1576.811 1.16 85487 17135 4 1576.810151 395.21 Sorting and assembly machinery component 50 homolog OS=Homo sapiens OX=9606 GN=SAMM50 PE=1 SV=3 5.98 2820.6 - 2.35E+06 - - - -0.5536 - 2.616 0.41 - 169.4 1 2 0 -0.0009 14 0 0 0 2.84E+07 2.45E+07 - - - 3.1444 0.9994 221125_WJC_METTL3_EV_vs_WT_F06.17139.17139.3 0.00957 20/44 R.TVITEEFK[136.11]VPDK[136.11].M sp|Q96I24|FUBP3_HUMAN 1 1420.7784 1.75 85489 17139 3 1420.774451 474.6001 Far upstream element-binding protein 3 OS=Homo sapiens OX=9606 GN=FUBP3 PE=1 SV=2 4.68 2821.1 - 3.58E+06 - - - -2.8125 - 3.072 0.399 - 379.3 1 2 1 -0.004 12 0 0 0 9.94E+07 5.69E+07 - - - 6.0983 1 221125_WJC_METTL3_EV_vs_WT_F06.17142.17142.3 2.39E-11 24/72 R.QHPQPYIFPDSPGGTSYER.Y "sp|Q9Y6M9|NDUB9_HUMAN,tr|A0A7I2V620|A0A7I2V620_HUMAN,tr|A0A3B3IT57|A0A3B3IT57_HUMAN,tr|E7EWZ0|E7EWZ0_HUMAN,tr|E9PF49|E9PF49_HUMAN,tr|E9PH64|E9PH64_HUMAN" 6 2175.0021 1.98 85492 17142 3 2175.002213 726.008 NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 9 OS=Homo sapiens OX=9606 GN=NDUFB9 PE=1 SV=3 5.32 2821.5 - 2.76E+06 - - - 0.0372 - 4.126 0.611 - 650.9 1 2 0 0.0001 19 0 0 0 4.13E+07 2.08E+07 - - - 8.8341 1 221125_WJC_METTL3_EV_vs_WT_F06.17147.17147.2 1.19E-12 17/38 R.FSSC[160.03]GGGGGSFGAGGGFGSR.S sp|P04264|K2C1_HUMAN 1 1764.7274 999 85495 17147 2 1764.726899 883.371 "Keratin, type II cytoskeletal 1 OS=Homo sapiens OX=9606 GN=KRT1 PE=1 SV=6" 8.25 2822.1 - 1.43E+06 - - - -0.3015 - 3.781 0.712 - 828.2 1 2 0 -0.0005 20 0 0 0 1.08E+08 0.00E+00 - - - 7.5695 0.9904 221125_WJC_METTL3_EV_vs_WT_F06.17150.17150.4 2.64E-05 13/120 S.VVLSGTAIHNFPTVQHQELAK.A "sp|Q9Y520|PRC2C_HUMAN,tr|E7EPN9|E7EPN9_HUMAN,tr|H7C5N8|H7C5N8_HUMAN,tr|A0A2R8Y7F4|A0A2R8Y7F4_HUMAN,tr|A0A2R8YET2|A0A2R8YET2_HUMAN" 5 2288.2277 4.81 85498 17150 4 2288.229292 573.0642 Protein PRRC2C OS=Homo sapiens OX=9606 GN=PRRC2C PE=1 SV=4 6.89 2822.5 - 1.05E+06 - - - 0.6887 - 2.417 0.437 - 62.5 1 1 0 0.0016 21 0 0 0 7.47E+06 1.55E+06 - - - 3.321 1 221125_WJC_METTL3_EV_vs_WT_F06.17152.17152.3 8.79E-15 18/96 K.LVQDVANNTNEEAGDGTTTATVLAR.S "sp|P10809|CH60_HUMAN,tr|C9JL25|C9JL25_HUMAN,tr|A0A7I2V2X6|A0A7I2V2X6_HUMAN,tr|A0A7I2YQK6|A0A7I2YQK6_HUMAN,tr|A0A7I2V599|A0A7I2V599_HUMAN,tr|E7EXB4|E7EXB4_HUMAN,tr|A0A7I2YQ71|A0A7I2YQ71_HUMAN,tr|E7ESH4|E7ESH4_HUMAN,tr|A0A7I2V5M1|A0A7I2V5M1_HUMAN,tr|A0A7I2V5K3|A0A7I2V5K3_HUMAN,tr|A0A7I2V369|A0A7I2V369_HUMAN" 11 2559.2413 2.12 85499 17152 3 2559.235064 854.0877 "60 kDa heat shock protein, mitochondrial OS=Homo sapiens OX=9606 GN=HSPD1 PE=1 SV=2" 3.92 2822.7 - 7.01E+06 - - - -2.4183 - 3.731 0.718 - 389.3 1 2 0 -0.0062 25 0 0 0 4.51E+08 2.12E+08 - - - 9.5725 0.9918 221125_WJC_METTL3_EV_vs_WT_F06.17154.17154.4 0.000323 16/78 K.DVVVQHVHFDGLGR[166.11].T sp|Q9Y512|SAM50_HUMAN 1 1586.8193 1.17 85500 17154 4 1586.818632 397.7121 Sorting and assembly machinery component 50 homolog OS=Homo sapiens OX=9606 GN=SAMM50 PE=1 SV=3 5.98 2822.9 - 1.94E+06 - - - -0.4172 - 2.116 0.2 - 142.9 1 2 0 -0.0007 14 0 0 0 2.86E+07 2.45E+07 - - - 1.2394 0.9987 221125_WJC_METTL3_EV_vs_WT_F06.17155.17155.3 3.05E-06 17/56 R.SATNTTLPHMLMSQR.V "sp|Q8WXI9|P66B_HUMAN,tr|A0A0U1RRM1|A0A0U1RRM1_HUMAN,tr|A0A0U1RR30|A0A0U1RR30_HUMAN" 3 1686.8182 3.88 85501 17155 3 1687.819046 563.28 Transcriptional repressor p66-beta OS=Homo sapiens OX=9606 GN=GATAD2B PE=1 SV=1 9.49 2823.1 - 1.50E+06 - - - 593.3574 - 3.177 0.454 - 482.1 1 2 0 1.0009 15 0 0 0 7.92E+07 2.04E+07 - - - 6.3407 0.9944 221125_WJC_METTL3_EV_vs_WT_F06.17157.17157.3 2.06E-06 15/68 S.SELVSWADGGQHSSIHPA.- "sp|O00746|NDKM_HUMAN,tr|Q4TT34|Q4TT34_HUMAN,tr|A0A087WVT9|A0A087WVT9_HUMAN" 3 1876.8704 - 85503 17157 3 1876.86563 626.6307 "Nucleoside diphosphate kinase, mitochondrial OS=Homo sapiens OX=9606 GN=NME4 PE=1 SV=1" 5.14 2823.2 - 1.59E+06 - - - -2.5361 - 3.044 0.515 - 193.6 1 1 0 -0.0048 18 0 0 0 - - - - - 7.0523 0.9599 221125_WJC_METTL3_EV_vs_WT_F06.17158.17158.3 1.09E-06 15/72 F.SGVPDRFSGSGSGTDFTLK.L "sp|A2NJV5|KV229_HUMAN,sp|A0A087WW87|KV240_HUMAN,sp|P06310|KV230_HUMAN,sp|A0A075B6S2|KVD29_HUMAN,sp|P01614|KVD40_HUMAN,sp|P01615|KVD28_HUMAN,sp|A0A075B6S6|KVD30_HUMAN,sp|A0A075B6P5|KV228_HUMAN,sp|A0A0A0MRZ7|KVD26_HUMAN" 9 1913.9119 236.49 85504 17158 3 1913.9167 638.9779 Immunoglobulin kappa variable 2-29 OS=Homo sapiens OX=9606 GN=IGKV2-29 PE=3 SV=2 5.68 2823.4 - 1.22E+06 - - - 2.4975 - 2.636 0.494 - 167.1 1 1 1 0.0048 19 0 0 0 2.56E+08 1.08E+06 - - - 6.4276 1 221125_WJC_METTL3_EV_vs_WT_F06.17167.17167.3 2.51E-09 23/72 R.QHPQPYIFPDSPGGTSYER[166.11].Y "sp|Q9Y6M9|NDUB9_HUMAN,tr|A0A7I2V620|A0A7I2V620_HUMAN,tr|A0A3B3IT57|A0A3B3IT57_HUMAN,tr|E7EWZ0|E7EWZ0_HUMAN,tr|E9PF49|E9PF49_HUMAN,tr|E9PH64|E9PH64_HUMAN" 6 2185.0104 1.93 85511 17167 3 2185.011144 729.3441 NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 9 OS=Homo sapiens OX=9606 GN=NDUFB9 PE=1 SV=3 5.32 2824.5 - 1.29E+06 - - - 0.3396 - 3.813 0.591 - 607 1 2 0 0.0007 19 0 0 0 4.13E+07 2.14E+07 - - - 8.4171 0.9561 221125_WJC_METTL3_EV_vs_WT_F06.17168.17168.3 0.0735 Nov-36 R.K[136.11]QVEEIFNLK[136.11].F "sp|P78347|GTF2I_HUMAN,tr|A0A494C0Q7|A0A494C0Q7_HUMAN,tr|A0A494C1K3|A0A494C1K3_HUMAN" 3 1262.7205 1.41 85512 17168 3 1262.717072 421.9141 General transcription factor II-I OS=Homo sapiens OX=9606 GN=GTF2I PE=1 SV=2 6.14 2824.6 - 853975 - - - -2.7449 - 1.883 0.107 - 240 1 2 0 -0.0035 10 0 0 0 1.55E+07 1.10E+07 - - - 1.5802 1 221125_WJC_METTL3_EV_vs_WT_F06.17170.17170.3 6.62E-13 25/108 R.ATAPVPTVGEGYGYGHESELSQASAAAR[166.11].N "sp|Q9BWF3|RBM4_HUMAN,tr|E9PB51|E9PB51_HUMAN" 2 2785.3183 1.49 85514 17170 3 2786.318441 929.4467 RNA-binding protein 4 OS=Homo sapiens OX=9606 GN=RBM4 PE=1 SV=1 4.75 2824.9 - 557637 - - - 359.0864 - 3.931 0.683 - 382.8 1 2 0 1.0002 28 0 0 0 6.52E+07 4.39E+07 - - - 9.0271 1 221125_WJC_METTL3_EV_vs_WT_F06.17175.17175.3 2.63E-13 21/96 K.LVQDVANNTNEEAGDGTTTATVLAR[166.11].S "sp|P10809|CH60_HUMAN,tr|C9JL25|C9JL25_HUMAN,tr|A0A7I2V2X6|A0A7I2V2X6_HUMAN,tr|A0A7I2YQK6|A0A7I2YQK6_HUMAN,tr|A0A7I2V599|A0A7I2V599_HUMAN,tr|E7EXB4|E7EXB4_HUMAN,tr|A0A7I2YQ71|A0A7I2YQ71_HUMAN,tr|E7ESH4|E7ESH4_HUMAN,tr|A0A7I2V5M1|A0A7I2V5M1_HUMAN,tr|A0A7I2V5K3|A0A7I2V5K3_HUMAN,tr|A0A7I2V369|A0A7I2V369_HUMAN" 11 2569.2495 1.99 85517 17175 3 2569.244301 857.4238 "60 kDa heat shock protein, mitochondrial OS=Homo sapiens OX=9606 GN=HSPD1 PE=1 SV=2" 3.92 2825.4 - 4.61E+06 - - - -2.0325 - 3.897 0.69 - 648.4 1 2 0 -0.0052 25 0 0 0 9.32E+07 4.68E+07 - - - 9.3607 1 221125_WJC_METTL3_EV_vs_WT_F06.17176.17176.3 4.23E-17 32/108 R.ATAPVPTVGEGYGYGHESELSQASAAAR.N "sp|Q9BWF3|RBM4_HUMAN,tr|E9PB51|E9PB51_HUMAN" 2 2775.31 1.49 85518 17176 3 2775.310382 926.1106 RNA-binding protein 4 OS=Homo sapiens OX=9606 GN=RBM4 PE=1 SV=1 4.75 2825.6 - 2.74E+06 - - - 0.1373 - 5.177 0.761 - 760.4 1 2 0 0.0004 28 0 0 0 6.52E+07 4.39E+07 - - - 10.8071 1 221125_WJC_METTL3_EV_vs_WT_F06.17178.17178.2 1.47E-11 20/32 R.SGGGFSSGSAGIINYQR.R sp|P04264|K2C1_HUMAN 1 1656.7856 939.45 85520 17178 2 1656.785461 829.4001 "Keratin, type II cytoskeletal 1 OS=Homo sapiens OX=9606 GN=KRT1 PE=1 SV=6" 8.46 2825.7 - 1.87E+06 - - - -0.0827 - 3.516 0.675 - 1509.6 1 2 0 -0.0001 17 0 0 0 7.30E+08 7.77E+05 - - - 7.1177 0.9932 221125_WJC_METTL3_EV_vs_WT_F06.17179.17179.3 0.0226 Oct-36 R.KQVEEIFNLK.F "sp|P78347|GTF2I_HUMAN,tr|A0A494C0Q7|A0A494C0Q7_HUMAN,tr|A0A494C1K3|A0A494C1K3_HUMAN" 3 1246.6921 1.14 85521 17179 3 1246.691483 416.5713 General transcription factor II-I OS=Homo sapiens OX=9606 GN=GTF2I PE=1 SV=2 6.14 2825.9 - 1.47E+06 - - - -0.5254 - 1.928 0.142 - 198.5 1 2 0 -0.0007 10 0 0 0 1.56E+07 1.37E+07 - - - 2.0402 1 221125_WJC_METTL3_EV_vs_WT_F06.17183.17183.4 5.61E-07 19/78 K.HWPFQVINDGDK[136.11]PK[136.11].V "sp|P0DMV8|HS71A_HUMAN,sp|P0DMV9|HS71B_HUMAN,tr|A0A0G2JIW1|A0A0G2JIW1_HUMAN" 3 1695.8704 0.14 85525 17183 4 1695.870218 424.9749 Heat shock 70 kDa protein 1A OS=Homo sapiens OX=9606 GN=HSPA1A PE=1 SV=1 6.75 2826.3 - 935385 - - - -0.1014 - 2.6 0.514 - 280.9 1 2 0 -0.0002 14 0 0 0 1.66E+08 1.21E+09 - - - 4.0476 0.9878 221125_WJC_METTL3_EV_vs_WT_F06.17184.17184.3 0.00102 13/56 H.VLC[160.03]HNC[160.03]AVEFNFGQK.E "sp|Q00839|HNRPU_HUMAN,tr|A0A1W2PQL0|A0A1W2PQL0_HUMAN,tr|A0A1W2PPL4|A0A1W2PPL4_HUMAN,tr|A0A1W2PQ74|A0A1W2PQ74_HUMAN,tr|Q5RI18|Q5RI18_HUMAN,tr|A0A1W2PP35|A0A1W2PP35_HUMAN,tr|A0A1W2PPS1|A0A1W2PPS1_HUMAN,tr|A0A1W2PRZ7|A0A1W2PRZ7_HUMAN,tr|A0A1W2PPH7|A0A1W2PPH7_HUMAN,tr|A0A1W2PP34|A0A1W2PP34_HUMAN,tr|A0A1X7SBS1|A0A1X7SBS1_HUMAN" 11 1821.8291 0.81 85526 17184 3 1821.828576 608.2836 Heterogeneous nuclear ribonucleoprotein U OS=Homo sapiens OX=9606 GN=HNRNPU PE=1 SV=6 6.7 2826.5 - 880510 - - - -0.2657 - 2.393 0.379 - 172.1 1 1 0 -0.0005 15 0 0 0 1.07E+07 1.33E+07 - - - 5.0421 0.9964 221125_WJC_METTL3_EV_vs_WT_F06.17186.17186.3 7.43E-06 17/60 L.QDDAHPTLVTYADHSK[136.11].L "sp|Q86U44|MTA70_HUMAN,tr|F5H6D8|F5H6D8_HUMAN,tr|H0YFV6|H0YFV6_HUMAN,tr|B4DTN4|B4DTN4_HUMAN" 4 1804.8471 0.14 85528 17186 3 1804.847209 602.623 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 5.13 2826.7 - 670379 - - - 0.0371 - 2.877 0.456 - 440.9 1 1 0 0.0001 16 0 0 0 7.29E+05 5.19E+06 - - - 6.3354 1 221125_WJC_METTL3_EV_vs_WT_F06.17187.17187.2 7.01E-10 17/34 K.YVHYEIDAC[160.03]MDSEAPGSK[136.11].D "sp|Q86U44|MTA70_HUMAN,tr|H0YFV6|H0YFV6_HUMAN" 2 2078.8805 0.001 85529 17187 2 2078.881841 1040.4475 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 4.31 2826.9 - 535894 - - - 0.6489 - 3.729 0.738 - 546.7 1 2 0 0.0013 18 0 0 0 0.00E+00 6.52E+07 - - - 7.7272 0.9999 221125_WJC_METTL3_EV_vs_WT_F06.17189.17189.3 3.59E-07 14/52 K.SGK[136.11]WEGLVYAPPGK[136.11].E "sp|Q9Y2W1|TR150_HUMAN,tr|A0A3B3ITZ9|A0A3B3ITZ9_HUMAN" 2 1503.8057 2.57 85530 17189 3 1503.805438 502.2758 Thyroid hormone receptor-associated protein 3 OS=Homo sapiens OX=9606 GN=THRAP3 PE=1 SV=2 8.22 2827.1 - 2.40E+06 - - - -0.151 - 2.652 0.504 - 198.1 1 2 1 -0.0002 14 0 0 0 1.89E+09 7.34E+08 - - - 6.751 1 221125_WJC_METTL3_EV_vs_WT_F06.17191.17191.3 1.18E-06 17/52 K.HWPFQVINDGDK[136.11]PK[136.11].V "sp|P0DMV8|HS71A_HUMAN,sp|P0DMV9|HS71B_HUMAN,tr|A0A0G2JIW1|A0A0G2JIW1_HUMAN" 3 1695.8704 0.13 85531 17191 3 1695.87272 566.2974 Heat shock 70 kDa protein 1A OS=Homo sapiens OX=9606 GN=HSPA1A PE=1 SV=1 6.75 2827.3 - 3.24E+06 - - - 1.3739 - 3.048 0.534 - 525.1 1 2 0 0.0023 14 0 0 0 5.34E+08 4.20E+09 - - - 7.4547 1 221125_WJC_METTL3_EV_vs_WT_F06.17192.17192.3 0.0031 13/64 R.SGGGFSSGSAGIINYQR.R sp|P04264|K2C1_HUMAN 1 1656.7856 142.1 85532 17192 3 1656.787061 553.2691 "Keratin, type II cytoskeletal 1 OS=Homo sapiens OX=9606 GN=KRT1 PE=1 SV=6" 8.46 2827.4 - 2.58E+06 - - - 0.883 - 2.619 0.45 - 192.3 1 2 0 0.0015 17 0 0 0 1.62E+08 1.14E+06 - - - 5.989 0.9994 221125_WJC_METTL3_EV_vs_WT_F06.17193.17193.4 0.0403 Oct-90 R.AELHPVELKPFQDYQK.L sp|P48634|PRC2A_HUMAN 1 1940.9996 1.33 85533 17193 4 1941.000005 486.2572 Protein PRRC2A OS=Homo sapiens OX=9606 GN=PRRC2A PE=1 SV=3 5.45 2827.4 - 2.29E+06 - - - 0.202 - 2.116 0.321 - 67.5 1 2 0 0.0004 16 0 0 0 6.22E+07 4.68E+07 - - - 2.2839 1 221125_WJC_METTL3_EV_vs_WT_F06.17194.17194.3 1.57E-08 16/52 K.HMNLILC[160.03]DC[160.03]DEFR[166.11]K[136.11].L "sp|P63162|RSMN_HUMAN,sp|P14678|RSMB_HUMAN,tr|J3KRY3|J3KRY3_HUMAN,tr|J3QLE5|J3QLE5_HUMAN,tr|S4R3P3|S4R3P3_HUMAN" 5 1867.8498 1.06 85534 17194 3 1867.846444 623.6239 Small nuclear ribonucleoprotein-associated protein N OS=Homo sapiens OX=9606 GN=SNRPN PE=1 SV=1 5.38 2827.5 - 2.16E+06 - - - -1.8047 - 3.008 0.676 - 400.7 1 2 0 -0.0034 14 0 0 0 8.26E+07 7.78E+07 - - - 9.0025 0.9999 221125_WJC_METTL3_EV_vs_WT_F06.17196.17196.3 0.0259 19/64 K.QGTQYTFSSIER[166.11]EEYGK[136.11].L sp|Q08945|SSRP1_HUMAN 1 2039.9555 0.29 85536 17196 3 2039.954443 680.9924 FACT complex subunit SSRP1 OS=Homo sapiens OX=9606 GN=SSRP1 PE=1 SV=1 4.79 2827.7 - 1.48E+06 - - - -0.528 - 3.763 0.489 - 576.3 1 2 1 -0.0011 17 0 0 0 1.04E+07 3.59E+07 - - - 7.3395 1 221125_WJC_METTL3_EV_vs_WT_F06.17197.17197.3 0.000212 20/80 R.SSPYGTLK[136.11]PEEMSGPGLAEPK[136.11].A "sp|Q5JSZ5|PRC2B_HUMAN,tr|A0A804HKC3|A0A804HKC3_HUMAN,tr|A0A804HJR4|A0A804HJR4_HUMAN" 3 2190.0849 1.76 85537 17197 3 2190.0878 731.0356 Protein PRRC2B OS=Homo sapiens OX=9606 GN=PRRC2B PE=1 SV=2 4.78 2827.8 - 1.17E+06 - - - 1.3077 - 3.591 0.504 - 347.2 1 2 0 0.0029 21 0 0 0 3.69E+07 2.09E+07 - - - 7.2233 0.9795 221125_WJC_METTL3_EV_vs_WT_F06.17198.17198.3 0.00106 Sep-32 K.LVKEEVFWR.N sp|Q96A49|SYAP1_HUMAN 1 1204.6604 1.06 85538 17198 3 1204.65865 402.5608 Synapse-associated protein 1 OS=Homo sapiens OX=9606 GN=SYAP1 PE=1 SV=1 6.14 2828 - 758530 - - - -1.4892 - 1.758 0.199 - 119.5 1 2 1 -0.0018 9 0 0 0 5.82E+06 5.48E+06 - - - 2.4585 0.9978 221125_WJC_METTL3_EV_vs_WT_F06.17199.17199.3 0.00252 Sep-32 K.LVK[136.11]EEVFWR[166.11].N sp|Q96A49|SYAP1_HUMAN 1 1222.6829 1.06 85539 17199 3 1222.681317 408.5682 Synapse-associated protein 1 OS=Homo sapiens OX=9606 GN=SYAP1 PE=1 SV=1 6.14 2828.1 - 746609 - - - -1.3061 - 1.9 0.313 - 124.1 1 2 1 -0.0016 9 0 0 0 5.82E+06 5.48E+06 - - - 3.9636 0.9996 221125_WJC_METTL3_EV_vs_WT_F06.17201.17201.3 5.55E-06 16/52 K.HMNLILC[160.03]DC[160.03]DEFRK.L "sp|P63162|RSMN_HUMAN,sp|P14678|RSMB_HUMAN,tr|J3KRY3|J3KRY3_HUMAN,tr|J3QLE5|J3QLE5_HUMAN,tr|S4R3P3|S4R3P3_HUMAN" 5 1849.8273 0.71 85540 17201 3 1850.828781 617.6164 Small nuclear ribonucleoprotein-associated protein N OS=Homo sapiens OX=9606 GN=SNRPN PE=1 SV=1 5.38 2828.3 - 1.56E+06 - - - 541.3673 - 3.123 0.576 - 436.4 1 2 0 1.0014 14 0 0 0 7.41E+07 1.05E+08 - - - 7.7108 1 221125_WJC_METTL3_EV_vs_WT_F06.17203.17203.4 1.23E-06 14/90 R.AELHPVELK[136.11]PFQDYQK[136.11].L sp|P48634|PRC2A_HUMAN 1 1957.028 1.46 85542 17203 4 1957.029278 490.2643 Protein PRRC2A OS=Homo sapiens OX=9606 GN=PRRC2A PE=1 SV=3 5.45 2828.5 - 1.78E+06 - - - 0.6464 - 2.561 0.501 - 105.8 1 2 0 0.0013 16 0 0 0 4.64E+07 3.17E+07 - - - 3.9176 1 221125_WJC_METTL3_EV_vs_WT_F06.17205.17205.4 2.79E-09 18/78 K.HMNLILC[160.03]DC[160.03]DEFR[166.11]K[136.11].L "sp|P63162|RSMN_HUMAN,sp|P14678|RSMB_HUMAN,tr|J3KRY3|J3KRY3_HUMAN,tr|J3QLE5|J3QLE5_HUMAN,tr|S4R3P3|S4R3P3_HUMAN" 5 1867.8498 0.74 85544 17205 4 1867.850244 467.9697 Small nuclear ribonucleoprotein-associated protein N OS=Homo sapiens OX=9606 GN=SNRPN PE=1 SV=1 5.38 2828.7 - 1.41E+06 - - - 0.2297 - 3.063 0.624 - 405.8 1 2 0 0.0004 14 0 0 0 2.35E+07 3.18E+07 - - - 5.0646 0.9998 221125_WJC_METTL3_EV_vs_WT_F06.17206.17206.3 0.000239 17/60 R.AELHPVELKPFQDYQK.L sp|P48634|PRC2A_HUMAN 1 1940.9996 1.72 85545 17206 3 1941.007986 648.0071 Protein PRRC2A OS=Homo sapiens OX=9606 GN=PRRC2A PE=1 SV=3 5.45 2828.8 - 772348 - - - 4.3138 - 3.233 0.491 - 326.1 1 2 0 0.0084 16 0 0 0 2.61E+07 1.52E+07 - - - 7.0227 1 221125_WJC_METTL3_EV_vs_WT_F06.17207.17207.4 1.19E-05 16/78 K.HMNLILC[160.03]DC[160.03]DEFRK.L "sp|P63162|RSMN_HUMAN,sp|P14678|RSMB_HUMAN,tr|J3KRY3|J3KRY3_HUMAN,tr|J3QLE5|J3QLE5_HUMAN,tr|S4R3P3|S4R3P3_HUMAN" 5 1849.8273 0.74 85546 17207 4 1849.827677 463.4641 Small nuclear ribonucleoprotein-associated protein N OS=Homo sapiens OX=9606 GN=SNRPN PE=1 SV=1 5.38 2828.9 - 761148 - - - 0.1795 - 2.871 0.581 - 328.9 1 2 0 0.0003 14 0 0 0 2.33E+07 3.16E+07 - - - 4.6668 0.9991 221125_WJC_METTL3_EV_vs_WT_F06.17208.17208.4 0.00874 Oct-90 R.VKAEEDKIPLLVVGNK.S "sp|P11234|RALB_HUMAN,tr|C9J6B1|C9J6B1_HUMAN,tr|C9JQB3|C9JQB3_HUMAN" 3 1751.0193 1.06 85547 17208 4 1751.01936 438.7621 Ras-related protein Ral-B OS=Homo sapiens OX=9606 GN=RALB PE=1 SV=1 6.15 2829.1 - 397642 - - - 0.0423 - 1.679 0.383 - 69.6 1 2 2 0.0001 16 0 0 0 5.34E+06 5.06E+06 - - - 2.7422 1 221125_WJC_METTL3_EV_vs_WT_F06.17218.17218.2 3.12E-09 28-Dec K.NSSQDDLFPTSDTPR.A sp|Q9H6T3|RPAP3_HUMAN 1 1678.7435 1.24 85555 17218 2 1678.738581 840.379 RNA polymerase II-associated protein 3 OS=Homo sapiens OX=9606 GN=RPAP3 PE=1 SV=2 3.93 2830.2 - 649730 - - - -2.9051 - 2.753 0.654 - 276 1 2 0 -0.0049 15 0 0 0 9.83E+06 7.95E+06 - - - 6.3597 1 221125_WJC_METTL3_EV_vs_WT_F06.17219.17219.2 4.49E-06 18/36 F.SGVPDRFSGSGSGTDFTLK.L "sp|A2NJV5|KV229_HUMAN,sp|A0A087WW87|KV240_HUMAN,sp|P06310|KV230_HUMAN,sp|A0A075B6S2|KVD29_HUMAN,sp|P01614|KVD40_HUMAN,sp|P01615|KVD28_HUMAN,sp|A0A075B6S6|KVD30_HUMAN,sp|A0A075B6P5|KV228_HUMAN,sp|A0A0A0MRZ7|KVD26_HUMAN" 9 1913.9119 999 85556 17219 2 1913.908245 957.9632 Immunoglobulin kappa variable 2-29 OS=Homo sapiens OX=9606 GN=IGKV2-29 PE=3 SV=2 5.68 2830.3 - 598231 - - - -1.9202 - 3.173 0.61 - 382.9 1 1 1 -0.0037 19 0 0 0 5.54E+06 0.00E+00 - - - 6.3841 1 221125_WJC_METTL3_EV_vs_WT_F06.17220.17220.2 9.98E-09 28-Nov K.NSSQDDLFPTSDTPR[166.11].A sp|Q9H6T3|RPAP3_HUMAN 1 1688.7517 1.38 85557 17220 2 1688.749757 845.3831 RNA polymerase II-associated protein 3 OS=Homo sapiens OX=9606 GN=RPAP3 PE=1 SV=2 3.93 2830.4 - 595609 - - - -1.1671 - 2.743 0.671 - 286.1 1 2 0 -0.002 15 0 0 0 1.10E+07 7.95E+06 - - - 6.4772 0.9596 221125_WJC_METTL3_EV_vs_WT_F06.17222.17222.4 0.0283 Dec-96 R.GISTKPVYIPEVELNHK.L "sp|Q14258|TRI25_HUMAN,tr|A0A3B3IUA7|A0A3B3IUA7_HUMAN" 2 1923.0466 0.95 85559 17222 4 1923.046561 481.7689 E3 ubiquitin\ISG15 ligase TRIM25 OS=Homo sapiens OX=9606 GN=TRIM25 PE=1 SV=2 6.76 2830.7 - 547276 - - - -0.001 - 1.885 0.143 - 86.9 1 2 0 0 17 0 0 0 8.37E+06 8.80E+06 - - - 0.6908 0.9812 221125_WJC_METTL3_EV_vs_WT_F06.17223.17223.4 0.0509 Oct-90 M.PALPLDQLQITHK[136.11]DPK[136.11].T "sp|Q9H1I8|ASCC2_HUMAN,tr|F2Z2W4|F2Z2W4_HUMAN,tr|B1AH59|B1AH59_HUMAN,tr|F8WAQ6|F8WAQ6_HUMAN" 4 1829.0382 2.55 85560 17223 4 1829.041062 458.2668 Activating signal cointegrator 1 complex subunit 2 OS=Homo sapiens OX=9606 GN=ASCC2 PE=1 SV=3 7.17 2830.8 - 416954 - - - 1.5735 - 1.86 0.237 - 81.8 1 2 1 0.0029 16 0 0 0 1.52E+07 5.96E+06 - - - 1.5067 0.8552 221125_WJC_METTL3_EV_vs_WT_F06.17225.17225.2 2.17 18-Jul R.K[136.11]QVEEIFNLK[136.11].F "sp|P78347|GTF2I_HUMAN,tr|A0A494C0Q7|A0A494C0Q7_HUMAN,tr|A0A494C1K3|A0A494C1K3_HUMAN" 3 1262.7205 1.51 85562 17225 2 1262.724379 632.3675 General transcription factor II-I OS=Homo sapiens OX=9606 GN=GTF2I PE=1 SV=2 6.14 2831.1 - 260666 - - - 3.0418 - 1.192 0.037 - 123.9 1 2 0 0.0038 10 0 0 0 7.48E+06 4.94E+06 - - - -0.1967 0.8715 221125_WJC_METTL3_EV_vs_WT_F06.17227.17227.3 0.0539 Jul-64 R.VKPAPDETSFSEALLKR.N "sp|Q12905|ILF2_HUMAN,tr|B4DY09|B4DY09_HUMAN,tr|X6R6Z1|X6R6Z1_HUMAN,tr|A0A0A0MRL0|A0A0A0MRL0_HUMAN" 4 1887.0102 1.75 85563 17227 3 1887.008119 630.0107 Interleukin enhancer-binding factor 2 OS=Homo sapiens OX=9606 GN=ILF2 PE=1 SV=2 6.15 2831.4 - 472742 - - - -1.0911 - 1.432 0.078 - 29.9 1 2 0 -0.0021 17 0 0 0 3.55E+08 2.02E+08 - - - 0.3162 1 221125_WJC_METTL3_EV_vs_WT_F06.17229.17229.3 8.45E-08 15/52 K.HWPFQVINDGDKPK.V "sp|P0DMV8|HS71A_HUMAN,sp|P0DMV9|HS71B_HUMAN,tr|A0A0G2JIW1|A0A0G2JIW1_HUMAN" 3 1679.842 0.13 85564 17229 3 1679.846076 560.9546 Heat shock 70 kDa protein 1A OS=Homo sapiens OX=9606 GN=HSPA1A PE=1 SV=1 6.75 2831.6 - 1.65E+06 - - - 2.4324 - 2.784 0.55 - 356.3 1 2 0 0.0041 14 0 0 0 5.34E+08 4.20E+09 - - - 7.3918 0.9998 221125_WJC_METTL3_EV_vs_WT_F06.17231.17231.3 4.03E-08 16/72 K.GSDLDPEEPIKVEEPEPVK.K sp|Q96BD8|SKA1_HUMAN 1 2106.0368 6.07 85566 17231 3 2106.041719 703.0196 Spindle and kinetochore-associated protein 1 OS=Homo sapiens OX=9606 GN=SKA1 PE=1 SV=1 4 2831.8 - 1.69E+06 - - - 2.3138 - 2.995 0.533 - 260 1 2 1 0.0049 19 0 0 0 3.24E+07 5.33E+06 - - - 7.176 1 221125_WJC_METTL3_EV_vs_WT_F06.17232.17232.2 2.02E-13 20/36 K.DSSLC[160.03]VSGETLAAGTSSPK.T "sp|P82094|TMF1_HUMAN,tr|F8WF45|F8WF45_HUMAN,tr|A0A2R8Y7M0|A0A2R8Y7M0_HUMAN" 3 1865.8677 1.63 85567 17232 2 1865.871586 933.9411 TATA element modulatory factor OS=Homo sapiens OX=9606 GN=TMF1 PE=1 SV=2 4.37 2831.9 - 1.69E+06 - - - 2.0971 - 3.352 0.746 - 933 1 2 0 0.0039 19 0 0 0 7.78E+07 4.79E+07 - - - 7.5235 0.9998 221125_WJC_METTL3_EV_vs_WT_F06.17233.17233.3 3.04E-07 13/52 R.ERDFTSLENTVEER.L sp|Q07065|CKAP4_HUMAN 1 1723.8013 1.33 85568 17233 3 1723.798074 575.6077 Cytoskeleton-associated protein 4 OS=Homo sapiens OX=9606 GN=CKAP4 PE=1 SV=2 4.25 2832 - 1.62E+06 - - - -1.8755 - 2.929 0.5 - 292.4 1 2 1 -0.0032 14 0 0 0 5.17E+07 3.90E+07 - - - 6.9696 0.9998 221125_WJC_METTL3_EV_vs_WT_F06.17234.17234.3 3.37E-05 17/36 R.VKDLESLFHR.S sp|Q03252|LMNB2_HUMAN 1 1242.6721 1.12 85569 17234 3 1242.671515 415.2313 Lamin-B2 OS=Homo sapiens OX=9606 GN=LMNB2 PE=1 SV=4 6.72 2832.1 - 1.49E+06 - - - -0.4474 - 2.619 0.404 - 398.8 1 2 1 -0.0006 10 0 0 0 2.27E+07 2.02E+07 - - - 5.8558 0.9999 221125_WJC_METTL3_EV_vs_WT_F06.17235.17235.3 1.58E-06 15/52 R.ER[166.11]DFTSLENTVEER[166.11].L sp|Q07065|CKAP4_HUMAN 1 1743.8178 1.32 85570 17235 3 1743.818097 582.2799 Cytoskeleton-associated protein 4 OS=Homo sapiens OX=9606 GN=CKAP4 PE=1 SV=2 4.25 2832.2 - 1.41E+06 - - - 0.1434 - 2.943 0.534 - 462.1 1 2 1 0.0003 14 0 0 0 5.17E+07 3.91E+07 - - - 7.3621 0.9999 221125_WJC_METTL3_EV_vs_WT_F06.17236.17236.3 0.00271 Dec-44 R.LIDLHSPSEIVK.Q "sp|P60866|RS20_HUMAN,tr|A0A7P0S5H5|A0A7P0S5H5_HUMAN,tr|G3XAN0|G3XAN0_HUMAN" 3 1349.7555 1.67 85571 17236 3 1349.75685 450.9258 40S ribosomal protein S20 OS=Homo sapiens OX=9606 GN=RPS20 PE=1 SV=1 5.32 2832.3 - 1.26E+06 - - - 1.0246 - 2.361 0.421 - 203.2 1 2 0 0.0014 12 0 0 0 2.93E+07 1.75E+07 - - - 5.6146 1 221125_WJC_METTL3_EV_vs_WT_F06.17237.17237.2 2.68E-12 18/36 K.DSSLC[160.03]VSGETLAAGTSSPK[136.11].T "sp|P82094|TMF1_HUMAN,tr|F8WF45|F8WF45_HUMAN,tr|A0A2R8Y7M0|A0A2R8Y7M0_HUMAN" 3 1873.8819 1.63 85572 17237 2 1873.878798 937.9482 TATA element modulatory factor OS=Homo sapiens OX=9606 GN=TMF1 PE=1 SV=2 4.37 2832.4 - 998552 - - - -1.641 - 3.378 0.706 - 828.4 1 2 0 -0.0031 19 0 0 0 7.78E+07 4.79E+07 - - - 7.2473 1 221125_WJC_METTL3_EV_vs_WT_F06.17246.17246.3 2.09E-10 19/60 R.VTELFMDNKNELDQC[160.03]K.S "sp|P52732|KIF11_HUMAN,tr|A0A7I2YQY4|A0A7I2YQY4_HUMAN,tr|A0A7I2V3A9|A0A7I2V3A9_HUMAN,tr|A0A7I2V3V3|A0A7I2V3V3_HUMAN" 4 1982.9078 3.6 85579 17246 3 1982.910574 661.9765 Kinesin-like protein KIF11 OS=Homo sapiens OX=9606 GN=KIF11 PE=1 SV=2 4.32 2833.5 - 8.62E+06 - - - 1.4176 - 3.748 0.662 - 613.3 1 2 1 0.0028 16 0 0 0 7.91E+07 2.20E+07 - - - 9.3099 0.9997 221125_WJC_METTL3_EV_vs_WT_F06.17247.17247.3 1.28E-06 17/40 K.FAAQELIEVK[136.11]R[166.11].G "sp|Q86U44|MTA70_HUMAN,tr|F5H6D8|F5H6D8_HUMAN,tr|H0YFV6|H0YFV6_HUMAN,tr|B4DTN4|B4DTN4_HUMAN" 4 1320.7521 0 85580 17247 3 1320.752568 441.258 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 6.14 2833.6 - 2.48E+06 - - - 0.3877 - 2.633 0.275 - 251.2 1 2 0 0.0005 11 0 0 0 6.49E+05 2.42E+08 - - - 4.3561 1 221125_WJC_METTL3_EV_vs_WT_F06.17251.17251.3 1.76E-17 26/96 Y.SNVEEADAAMAASPHAVDGNTVELK.R sp|Q13151|ROA0_HUMAN 1 2525.1704 3.71 85584 17251 3 2525.173708 842.7307 Heterogeneous nuclear ribonucleoprotein A0 OS=Homo sapiens OX=9606 GN=HNRNPA0 PE=1 SV=1 4.17 2834 - 1.38E+06 - - - 1.3116 - 5.299 0.725 - 536.7 1 1 0 0.0033 25 0 0 0 1.13E+07 3.06E+06 - - - 10.4585 0.9987 221125_WJC_METTL3_EV_vs_WT_F06.17253.17253.3 1.09 13/44 R.LIDLHSPSEIVK[136.11].Q "sp|P60866|RS20_HUMAN,tr|A0A7P0S5H5|A0A7P0S5H5_HUMAN,tr|G3XAN0|G3XAN0_HUMAN" 3 1357.7697 1.63 85586 17253 3 1357.77215 453.5972 40S ribosomal protein S20 OS=Homo sapiens OX=9606 GN=RPS20 PE=1 SV=1 5.32 2834.3 - 988444 - - - 1.8287 - 2.219 0.25 - 202.5 1 2 0 0.0025 12 0 0 0 2.86E+07 1.75E+07 - - - 3.5359 0.9999 221125_WJC_METTL3_EV_vs_WT_F06.17255.17255.3 2.70E-05 13/36 K.GNKPWISLPR.G "sp|P62701|RS4X_HUMAN,sp|P22090|RS4Y1_HUMAN,sp|Q8TD47|RS4Y2_HUMAN,tr|C9JEH7|C9JEH7_HUMAN" 4 1166.656 0.98 85588 17255 3 1166.656555 389.8926 "40S ribosomal protein S4, X isoform OS=Homo sapiens OX=9606 GN=RPS4X PE=1 SV=2" 11 2834.5 - 803128 - - - 0.4526 - 2.357 0.385 - 214 1 2 0 0.0005 10 0 0 0 2.03E+07 2.07E+07 - - - 5.3362 0.9997 221125_WJC_METTL3_EV_vs_WT_F06.17256.17256.2 0.00238 26-Sep K.HWPFQVINDGDK[136.11]PK[136.11].V "sp|P0DMV8|HS71A_HUMAN,sp|P0DMV9|HS71B_HUMAN,tr|A0A0G2JIW1|A0A0G2JIW1_HUMAN" 3 1695.8704 0.04 85589 17256 2 1695.871646 848.9425 Heat shock 70 kDa protein 1A OS=Homo sapiens OX=9606 GN=HSPA1A PE=1 SV=1 6.75 2834.6 - 495504 - - - 0.7406 - 1.701 0.459 - 152.7 1 2 0 0.0013 14 0 0 0 1.63E+07 3.84E+08 - - - 3.7638 1 221125_WJC_METTL3_EV_vs_WT_F06.17259.17259.3 1.03E-08 18/80 K.STPLSQPSANGVQTEGLDYDR.L "sp|Q8N8S7|ENAH_HUMAN,tr|A0A0U1RRM6|A0A0U1RRM6_HUMAN" 2 2234.0451 1.26 85590 17259 3 2234.041031 745.689 Protein enabled homolog OS=Homo sapiens OX=9606 GN=ENAH PE=1 SV=2 4.03 2835 - 2.47E+06 - - - -1.8299 - 3.289 0.529 - 313.3 1 2 0 -0.0041 21 0 0 0 3.28E+07 2.61E+07 - - - 7.2911 1 221125_WJC_METTL3_EV_vs_WT_F06.17260.17260.3 9.06E-07 18/80 K.STPLSQPSANGVQTEGLDYDR[166.11].L "sp|Q8N8S7|ENAH_HUMAN,tr|A0A0U1RRM6|A0A0U1RRM6_HUMAN" 2 2244.0534 1.26 85591 17260 3 2244.053813 749.0251 Protein enabled homolog OS=Homo sapiens OX=9606 GN=ENAH PE=1 SV=2 4.03 2835.1 - 2.01E+06 - - - 0.1889 - 3.24 0.56 - 258.2 1 2 0 0.0004 21 0 0 0 3.28E+07 2.61E+07 - - - 7.6017 0.9988 221125_WJC_METTL3_EV_vs_WT_F06.17262.17262.3 0.000173 Nov-56 R.ILNEMRDQYEQMAEK.N "sp|P08779|K1C16_HUMAN,tr|K7ENW6|K7ENW6_HUMAN" 2 1896.871 3.12 85593 17262 3 1896.871843 633.2976 "Keratin, type I cytoskeletal 16 OS=Homo sapiens OX=9606 GN=KRT16 PE=1 SV=4" 4.41 2835.3 - 1.06E+06 - - - 0.4529 - 2.019 0.357 - 147.8 1 2 1 0.0009 15 0 0 0 1.22E+07 3.91E+06 - - - 4.3533 0.9998 221125_WJC_METTL3_EV_vs_WT_F06.17264.17264.3 0.00867 Nov-36 K.GNK[136.11]PWISLPR[166.11].G "sp|P62701|RS4X_HUMAN,sp|P22090|RS4Y1_HUMAN,sp|Q8TD47|RS4Y2_HUMAN,tr|C9JEH7|C9JEH7_HUMAN" 4 1184.6785 0.98 85595 17264 3 1184.678691 395.9001 "40S ribosomal protein S4, X isoform OS=Homo sapiens OX=9606 GN=RPS4X PE=1 SV=2" 11 2835.6 - 968560 - - - 0.1638 - 2.186 0.338 - 122.2 1 2 0 0.0002 10 0 0 0 2.03E+07 2.07E+07 - - - 4.5923 0.9998 221125_WJC_METTL3_EV_vs_WT_F06.17266.17266.3 1.46E-08 18/60 R.GIYAYGFEKPSAIQQR.A "sp|Q14240|IF4A2_HUMAN,sp|P38919|IF4A3_HUMAN,sp|P60842|IF4A1_HUMAN,tr|J3KTB5|J3KTB5_HUMAN,tr|J3KT04|J3KT04_HUMAN,tr|J3KS93|J3KS93_HUMAN,tr|E7EMV8|E7EMV8_HUMAN,tr|J3KT12|J3KT12_HUMAN,tr|J3QKZ9|J3QKZ9_HUMAN,tr|J3QS69|J3QS69_HUMAN,tr|I3L3H2|I3L3H2_HUMAN,tr|J3QL43|J3QL43_HUMAN,tr|F8WE11|F8WE11_HUMAN,tr|E7EQG2|E7EQG2_HUMAN,tr|J3KS25|J3KS25_HUMAN,tr|E9PBH4|E9PBH4_HUMAN,tr|J3QLN6|J3QLN6_HUMAN,tr|J3QQP0|J3QQP0_HUMAN,tr|J3QR64|J3QR64_HUMAN,tr|J3KSN7|J3KSN7_HUMAN" 20 1826.9315 2.98 85597 17266 3 1826.941129 609.9845 Eukaryotic initiation factor 4A-II OS=Homo sapiens OX=9606 GN=EIF4A2 PE=1 SV=2 8.5 2835.8 - 765854 - - - 5.252 - 3.221 0.563 - 276.6 1 2 0 0.0096 16 0 0 0 1.05E+07 3.51E+06 - - - 7.8155 1 221125_WJC_METTL3_EV_vs_WT_F06.17272.17272.3 1.09E-09 21/68 R.AHPVFYQGTYSQALNDAK[136.11].R sp|Q96CS3|FAF2_HUMAN 1 2016.9785 2.58 85601 17272 3 2016.979255 673.3334 FAS-associated factor 2 OS=Homo sapiens OX=9606 GN=FAF2 PE=1 SV=2 6.79 2836.7 - 1.12E+06 - - - 0.3793 - 3.946 0.678 - 594.1 1 2 0 0.0008 18 0 0 0 6.51E+07 2.53E+07 - - - 9.517 0.9998 221125_WJC_METTL3_EV_vs_WT_F06.17273.17273.4 3.96E-05 22/72 R.C[160.03]ILPFDKETGFHR.G "sp|Q9GZT3|SLIRP_HUMAN,tr|H0YJW7|H0YJW7_HUMAN,tr|A0A087WUN7|A0A087WUN7_HUMAN,tr|G3V2S9|G3V2S9_HUMAN,tr|H0YJ40|H0YJ40_HUMAN,tr|G3V4X6|G3V4X6_HUMAN" 6 1618.7926 1.2 85602 17273 4 1618.792612 405.7054 "SRA stem-loop-interacting RNA-binding protein, mitochondrial OS=Homo sapiens OX=9606 GN=SLIRP PE=1 SV=1" 6.74 2836.8 - 1.36E+06 - - - 0.0093 - 3.03 0.457 - 677 1 2 1 0 13 0 0 0 1.01E+08 8.39E+07 - - - 3.6147 1 221125_WJC_METTL3_EV_vs_WT_F06.17274.17274.3 4.82E-08 15/68 R.SGQGFHGNSEVNAILSPR[166.11].S "sp|Q8TB72|PUM2_HUMAN,tr|C9JW01|C9JW01_HUMAN" 2 1878.9212 1.05 85603 17274 3 1878.924628 627.3143 Pumilio homolog 2 OS=Homo sapiens OX=9606 GN=PUM2 PE=1 SV=2 6.47 2836.9 - 1.80E+06 - - - 1.8282 - 3.022 0.55 - 212.4 1 2 0 0.0034 18 0 0 0 6.16E+07 5.87E+07 - - - 7.4249 1 221125_WJC_METTL3_EV_vs_WT_F06.17275.17275.4 2.89E-06 15/78 K.HWPFQVINDGDKPK.V "sp|P0DMV8|HS71A_HUMAN,sp|P0DMV9|HS71B_HUMAN,tr|A0A0G2JIW1|A0A0G2JIW1_HUMAN" 3 1679.842 0.14 85604 17275 4 1679.842987 420.9678 Heat shock 70 kDa protein 1A OS=Homo sapiens OX=9606 GN=HSPA1A PE=1 SV=1 6.75 2836.9 - 1.62E+06 - - - 0.5935 - 2.592 0.483 - 133.7 1 2 0 0.001 14 0 0 0 1.66E+08 1.21E+09 - - - 3.7764 0.9999 221125_WJC_METTL3_EV_vs_WT_F06.17276.17276.3 2.81E-05 19/48 R.RDVDFELIKVEGK.V "sp|P48643|TCPE_HUMAN,tr|E9PCA1|E9PCA1_HUMAN,tr|B7ZAR1|B7ZAR1_HUMAN,tr|E7ENZ3|E7ENZ3_HUMAN" 4 1546.8355 0.6 85605 17276 3 1546.837114 516.6191 T-complex protein 1 subunit epsilon OS=Homo sapiens OX=9606 GN=CCT5 PE=1 SV=1 4.78 2837.1 - 857748 - - - 1.0382 - 3.257 0.554 - 655.2 1 2 1 0.0016 13 0 0 0 3.81E+07 6.36E+07 - - - 7.9176 1 221125_WJC_METTL3_EV_vs_WT_F06.17280.17280.2 6.97E-13 15/40 K.STPLSQPSANGVQTEGLDYDR[166.11].L "sp|Q8N8S7|ENAH_HUMAN,tr|A0A0U1RRM6|A0A0U1RRM6_HUMAN" 2 2244.0534 1.37 85609 17280 2 2244.057619 1123.034 Protein enabled homolog OS=Homo sapiens OX=9606 GN=ENAH PE=1 SV=2 4.03 2837.6 - 436479 - - - 1.885 - 3.075 0.717 - 331.4 1 2 0 0.0042 21 0 0 0 7.74E+06 5.66E+06 - - - 7.0971 0.8808 221125_WJC_METTL3_EV_vs_WT_F06.17281.17281.3 0.196 Oct-60 R.VKAEEDKIPLLVVGNK.S "sp|P11234|RALB_HUMAN,tr|C9J6B1|C9J6B1_HUMAN,tr|C9JQB3|C9JQB3_HUMAN" 3 1751.0193 1.32 85610 17281 3 1751.021347 584.6804 Ras-related protein Ral-B OS=Homo sapiens OX=9606 GN=RALB PE=1 SV=1 6.15 2837.7 - 524188 - - - 1.177 - 1.414 0.167 - 52.8 1 2 2 0.0021 16 0 0 0 3.59E+06 2.72E+06 - - - 1.2902 0.9999 221125_WJC_METTL3_EV_vs_WT_F06.17285.17285.3 2.48E-07 17/48 R.C[160.03]ILPFDK[136.11]ETGFHR[166.11].G "sp|Q9GZT3|SLIRP_HUMAN,tr|H0YJW7|H0YJW7_HUMAN,tr|A0A087WUN7|A0A087WUN7_HUMAN,tr|G3V2S9|G3V2S9_HUMAN,tr|H0YJ40|H0YJ40_HUMAN,tr|G3V4X6|G3V4X6_HUMAN" 6 1636.8151 1.7 85612 17285 3 1636.81735 546.6123 "SRA stem-loop-interacting RNA-binding protein, mitochondrial OS=Homo sapiens OX=9606 GN=SLIRP PE=1 SV=1" 6.74 2838.1 - 1.41E+06 - - - 1.3948 - 3.162 0.531 - 397.8 1 2 1 0.0023 13 0 0 0 1.19E+08 6.97E+07 - - - 7.5807 0.9999 221125_WJC_METTL3_EV_vs_WT_F06.17286.17286.4 2.88E-07 21/72 R.C[160.03]ILPFDK[136.11]ETGFHR[166.11].G "sp|Q9GZT3|SLIRP_HUMAN,tr|H0YJW7|H0YJW7_HUMAN,tr|A0A087WUN7|A0A087WUN7_HUMAN,tr|G3V2S9|G3V2S9_HUMAN,tr|H0YJ40|H0YJ40_HUMAN,tr|G3V4X6|G3V4X6_HUMAN" 6 1636.8151 1.2 85613 17286 4 1636.816635 410.211 "SRA stem-loop-interacting RNA-binding protein, mitochondrial OS=Homo sapiens OX=9606 GN=SLIRP PE=1 SV=1" 6.74 2838.2 - 2.34E+06 - - - 0.958 - 3.521 0.547 - 581.9 1 2 1 0.0016 13 0 0 0 1.01E+08 8.39E+07 - - - 4.4534 1 221125_WJC_METTL3_EV_vs_WT_F06.17287.17287.3 9.65E-15 17/68 R.AHPVFYQGTYSQALNDAK.R sp|Q96CS3|FAF2_HUMAN 1 2008.9643 1.08 85614 17287 3 2008.967006 670.662 FAS-associated factor 2 OS=Homo sapiens OX=9606 GN=FAF2 PE=1 SV=2 6.79 2838.3 - 1.70E+06 - - - 1.3519 - 3.558 0.59 - 437.1 1 2 0 0.0027 18 0 0 0 1.79E+07 1.66E+07 - - - 8.2776 0.9997 221125_WJC_METTL3_EV_vs_WT_F06.17288.17288.3 1.45E-05 17/48 R.C[160.03]ILPFDKETGFHR.G "sp|Q9GZT3|SLIRP_HUMAN,tr|H0YJW7|H0YJW7_HUMAN,tr|A0A087WUN7|A0A087WUN7_HUMAN,tr|G3V2S9|G3V2S9_HUMAN,tr|H0YJ40|H0YJ40_HUMAN,tr|G3V4X6|G3V4X6_HUMAN" 6 1618.7926 1.52 85615 17288 3 1618.793625 540.6048 "SRA stem-loop-interacting RNA-binding protein, mitochondrial OS=Homo sapiens OX=9606 GN=SLIRP PE=1 SV=1" 6.74 2838.3 - 1.53E+06 - - - 0.635 - 2.739 0.407 - 393.4 1 2 1 0.001 13 0 0 0 1.08E+08 7.10E+07 - - - 5.8092 0.951 221125_WJC_METTL3_EV_vs_WT_F06.17290.17290.2 0.00581 16-Sep Q.VINDGDK[136.11]PK[136.11].V "sp|P0DMV8|HS71A_HUMAN,sp|P0DMV9|HS71B_HUMAN,tr|A0A0G2JIW1|A0A0G2JIW1_HUMAN" 3 1000.5524 0.13 85617 17290 2 1000.55418 501.2835 Heat shock 70 kDa protein 1A OS=Homo sapiens OX=9606 GN=HSPA1A PE=1 SV=1 5.93 2838.6 - 1.09E+06 - - - 1.769 - 1.63 0.37 - 228.4 1 1 0 0.0018 9 0 0 0 1.30E+07 1.04E+08 - - - 3.1868 0.9996 221125_WJC_METTL3_EV_vs_WT_F06.17293.17293.3 0.000203 15/76 K.AHPPVTSAPLSPPQPNDLYK.N sp|Q4VCS5|AMOT_HUMAN 1 2128.0953 2.56 85620 17293 3 2128.098029 710.3724 Angiomotin OS=Homo sapiens OX=9606 GN=AMOT PE=1 SV=1 6.79 2838.9 - 713193 - - - 1.2805 - 2.484 0.301 - 171.5 1 2 0 0.0027 20 0 0 0 1.40E+07 5.48E+06 - - - 4.1025 1 221125_WJC_METTL3_EV_vs_WT_F06.17294.17294.3 3.47E-18 32/72 R.C[160.03]ELC[160.03]DVSC[160.03]TGADAYAAHIR.G sp|Q96KR1|ZFR_HUMAN 1 2167.9085 0.26 85621 17294 3 2167.909847 723.6434 Zinc finger RNA-binding protein OS=Homo sapiens OX=9606 GN=ZFR PE=1 SV=2 4.54 2839.1 - 697705 - - - 0.6172 - 4.755 0.793 - 1787.4 1 2 0 0.0013 19 0 0 0 2.13E+07 8.08E+07 - - - 11.2114 0.9999 221125_WJC_METTL3_EV_vs_WT_F06.17301.17301.3 2.92E-06 14/68 R.SGQGFHGNSEVNAILSPR.S "sp|Q8TB72|PUM2_HUMAN,tr|C9JW01|C9JW01_HUMAN" 2 1868.9129 1.07 85626 17301 3 1868.918967 623.9783 Pumilio homolog 2 OS=Homo sapiens OX=9606 GN=PUM2 PE=1 SV=2 6.47 2840 - 2.16E+06 - - - 3.234 - 2.731 0.537 - 230.1 1 2 0 0.006 18 0 0 0 6.44E+07 6.02E+07 - - - 7.0271 0.9972 221125_WJC_METTL3_EV_vs_WT_F06.17303.17303.3 5.63E-07 Dec-60 H.SRPPVPEWDISQDPPK.H "sp|Q9H6R4|NOL6_HUMAN,tr|A0A0A0MRW6|A0A0A0MRW6_HUMAN" 2 1846.9214 1.27 85628 17303 3 1846.920837 616.6477 Nucleolar protein 6 OS=Homo sapiens OX=9606 GN=NOL6 PE=1 SV=2 4.56 2840.2 - 1.31E+06 - - - -0.2848 - 2.163 0.552 - 144.7 1 1 0 -0.0005 16 0 0 0 3.76E+07 2.95E+07 - - - 6.6737 1 221125_WJC_METTL3_EV_vs_WT_F06.17305.17305.3 1.97E-06 13/80 R.VQSC[160.03]PDPAVYGVVQSGDHIGR[166.11].T "sp|Q9C0C9|UBE2O_HUMAN,tr|K7ES11|K7ES11_HUMAN" 2 2250.0727 0.91 85630 17305 3 2250.073266 751.0315 (E3-independent) E2 ubiquitin-conjugating enzyme OS=Homo sapiens OX=9606 GN=UBE2O PE=1 SV=3 5.21 2840.4 - 681291 - - - 0.2582 - 2.884 0.568 - 175.3 1 2 0 0.0006 21 0 0 0 2.30E+07 2.53E+07 - - - 7.4118 1 221125_WJC_METTL3_EV_vs_WT_F06.17308.17308.2 1.64E-09 15/34 K.EAYMGNVLQGGEGQAPTR[166.11].Q "sp|P24752|THIL_HUMAN,tr|A0A5F9ZHL7|A0A5F9ZHL7_HUMAN,tr|A0A5F9ZHJ7|A0A5F9ZHJ7_HUMAN,tr|A0A5F9ZHH9|A0A5F9ZHH9_HUMAN,tr|A0A5F9ZHL1|A0A5F9ZHL1_HUMAN,tr|E9PRQ6|E9PRQ6_HUMAN,tr|H0YEL7|H0YEL7_HUMAN" 7 1886.882 2.93 85633 17308 2 1886.881542 944.4483 "Acetyl-CoA acetyltransferase, mitochondrial OS=Homo sapiens OX=9606 GN=ACAT1 PE=1 SV=1" 4.53 2840.8 - 380702 - - - -0.2592 - 3.078 0.735 - 664.7 1 2 0 -0.0005 18 0 0 0 1.25E+07 4.28E+06 - - - 7.2337 0.9999 221125_WJC_METTL3_EV_vs_WT_F06.17312.17312.4 8.28E-06 19/72 R.R[166.11]DVDFELIK[136.11]VEGK[136.11].V "sp|P48643|TCPE_HUMAN,tr|E9PCA1|E9PCA1_HUMAN,tr|B7ZAR1|B7ZAR1_HUMAN,tr|E7ENZ3|E7ENZ3_HUMAN" 4 1572.8722 0.54 85635 17312 4 1572.875391 394.2253 T-complex protein 1 subunit epsilon OS=Homo sapiens OX=9606 GN=CCT5 PE=1 SV=1 4.78 2841.4 - 1.27E+06 - - - 2.0428 - 3.201 0.561 - 368.8 1 2 1 0.0032 13 0 0 0 7.88E+06 1.45E+07 - - - 4.5394 0.9935 221125_WJC_METTL3_EV_vs_WT_F06.17314.17314.4 0.0097 8/102 K.FLSPVVPNYDNVHPNYHK.E "sp|Q9Y262|EIF3L_HUMAN,tr|B0QY89|B0QY89_HUMAN,tr|B0QY90|B0QY90_HUMAN" 3 2139.0538 0.82 85637 17314 4 2139.055702 535.7707 Eukaryotic translation initiation factor 3 subunit L OS=Homo sapiens OX=9606 GN=EIF3L PE=1 SV=1 6.92 2841.4 - 2.29E+06 - - - 0.9013 - 2.02 0.213 - 47.9 1 2 0 0.0019 18 0 0 0 3.97E+07 4.84E+07 - - - 1.3203 1 221125_WJC_METTL3_EV_vs_WT_F06.17315.17315.3 2.90E-15 23/60 R.FSGSGSGTDFTLKISR.V "sp|A2NJV5|KV229_HUMAN,sp|A0A087WW87|KV240_HUMAN,sp|P06310|KV230_HUMAN,sp|A0A075B6S2|KVD29_HUMAN,sp|P01614|KVD40_HUMAN,sp|P01615|KVD28_HUMAN,sp|A0A075B6S6|KVD30_HUMAN,sp|A0A075B6P5|KV228_HUMAN,sp|A0A0A0MRZ7|KVD26_HUMAN" 9 1658.8264 1.51 85638 17315 3 1658.834886 553.9494 Immunoglobulin kappa variable 2-29 OS=Homo sapiens OX=9606 GN=IGKV2-29 PE=3 SV=2 8.75 2841.6 - 753222 - - - 5.1157 - 4.241 0.563 - 504.2 1 2 1 0.0085 16 0 0 0 5.94E+08 3.92E+08 - - - 8.5217 0.9749 221125_WJC_METTL3_EV_vs_WT_F06.17320.17320.2 0.0181 14-Aug V.INDGDK[136.11]PK[136.11].V "sp|P0DMV8|HS71A_HUMAN,sp|P0DMV9|HS71B_HUMAN,tr|A0A0G2JIW1|A0A0G2JIW1_HUMAN" 3 901.484 0.1 85641 17320 2 901.483317 451.7493 Heat shock 70 kDa protein 1A OS=Homo sapiens OX=9606 GN=HSPA1A PE=1 SV=1 5.96 2842.2 - 903911 - - - -0.7532 - 1.711 0.354 - 118.9 1 1 0 -0.0007 8 0 0 0 6.04E+06 5.99E+07 - - - 3.2752 1 221125_WJC_METTL3_EV_vs_WT_F06.17324.17324.3 7.41E-05 16/60 K.TGSPGPELLFHEGQQK[136.11].R "sp|Q14202|ZMYM3_HUMAN,tr|A6NL54|A6NL54_HUMAN,tr|A6NHB5|A6NHB5_HUMAN,tr|A6NHN7|A6NHN7_HUMAN" 4 1731.8671 0.2 85645 17324 3 1731.866434 578.2963 Zinc finger MYM-type protein 3 OS=Homo sapiens OX=9606 GN=ZMYM3 PE=1 SV=2 5.37 2842.6 - 517335 - - - -0.4128 - 2.984 0.468 - 241.3 1 2 0 -0.0007 16 0 0 0 4.76E+06 2.36E+07 - - - 6.5627 0.8674 221125_WJC_METTL3_EV_vs_WT_F06.17330.17330.4 0.00236 20/96 K.LDK[136.11]AQIHDLVLVGGSTR[166.11].L "sp|P0DMV8|HS71A_HUMAN,sp|P0DMV9|HS71B_HUMAN,tr|V9GZ37|V9GZ37_HUMAN,tr|A0A0G2JIW1|A0A0G2JIW1_HUMAN" 4 1839.0333 0.12 85649 17330 4 1839.032924 460.7656 Heat shock 70 kDa protein 1A OS=Homo sapiens OX=9606 GN=HSPA1A PE=1 SV=1 6.75 2843.4 - 795318 - - - -0.2137 - 3.066 0.127 - 259.3 1 2 1 -0.0004 17 0 0 0 2.22E+07 1.79E+08 - - - 0.7203 0.9185 221125_WJC_METTL3_EV_vs_WT_F06.17331.17331.3 3.79E-05 22/76 R.QGGSVAQAPAGTSFVAPVGH.S "sp|Q8IWZ3|ANKH1_HUMAN,tr|A0A0A0MQZ8|A0A0A0MQZ8_HUMAN,tr|H0Y472|H0Y472_HUMAN,tr|H0Y7Y3|H0Y7Y3_HUMAN,tr|H0Y4P6|H0Y4P6_HUMAN,tr|H7C0V5|H7C0V5_HUMAN,tr|H0Y785|H0Y785_HUMAN,tr|H7C2E1|H7C2E1_HUMAN" 8 1836.9119 - 85650 17331 3 1836.923818 613.3112 Ankyrin repeat and KH domain-containing protein 1 OS=Homo sapiens OX=9606 GN=ANKHD1 PE=1 SV=1 6.74 2843.6 - 984116 - - - 6.5093 - 3.74 0.485 - 523.5 1 1 0 0.012 20 0 0 0 - - - - - 7.1441 1 221125_WJC_METTL3_EV_vs_WT_F06.17334.17334.4 9.05E-08 26/132 R.FAAHLIAGAPSEGSGALK[136.11]PELSR[166.11].R sp|Q8WTT2|NOC3L_HUMAN 1 2296.2294 0.69 85653 17334 4 2296.227278 575.0646 Nucleolar complex protein 3 homolog OS=Homo sapiens OX=9606 GN=NOC3L PE=1 SV=1 6.76 2843.9 - 1.02E+06 - - - -0.9459 - 4.808 0.543 - 418.5 1 2 0 -0.0022 23 0 0 0 1.75E+07 2.54E+07 - - - 4.4604 1 221125_WJC_METTL3_EV_vs_WT_F06.17336.17336.2 6.94E-11 19/38 R.QGGSVAQAPAGTSFVAPVGH.S "sp|Q8IWZ3|ANKH1_HUMAN,tr|A0A0A0MQZ8|A0A0A0MQZ8_HUMAN,tr|H0Y472|H0Y472_HUMAN,tr|H0Y7Y3|H0Y7Y3_HUMAN,tr|H0Y4P6|H0Y4P6_HUMAN,tr|H7C0V5|H7C0V5_HUMAN,tr|H0Y785|H0Y785_HUMAN,tr|H7C2E1|H7C2E1_HUMAN" 8 1836.9119 - 85655 17336 2 1836.915448 919.4632 Ankyrin repeat and KH domain-containing protein 1 OS=Homo sapiens OX=9606 GN=ANKHD1 PE=1 SV=1 6.74 2844.1 - 659467 - - - 1.9527 - 3.244 0.617 - 826.3 1 1 0 0.0036 20 0 0 0 - - - - - 6.4903 1 221125_WJC_METTL3_EV_vs_WT_F06.17337.17337.2 1.49E-10 15/36 K.SAAAEAPTDDQPTDLSLPK.N "sp|Q14865|ARI5B_HUMAN,tr|A0A7P0TAD2|A0A7P0TAD2_HUMAN" 2 1925.9218 2.34 85656 17337 2 1925.923884 963.9682 AT-rich interactive domain-containing protein 5B OS=Homo sapiens OX=9606 GN=ARID5B PE=1 SV=3 3.84 2844.3 - 226459 - - - 1.0738 - 3.221 0.692 - 580.8 1 2 0 0.0021 19 0 0 0 7.76E+06 3.32E+06 - - - 7.0272 0.9996 221125_WJC_METTL3_EV_vs_WT_F06.17340.17340.3 9.39E-07 24/64 K.LDK[136.11]AQIHDLVLVGGSTR[166.11].L "sp|P0DMV8|HS71A_HUMAN,sp|P0DMV9|HS71B_HUMAN,tr|V9GZ37|V9GZ37_HUMAN,tr|A0A0G2JIW1|A0A0G2JIW1_HUMAN" 4 1839.0333 0.12 85657 17340 3 1839.034948 614.0184 Heat shock 70 kDa protein 1A OS=Homo sapiens OX=9606 GN=HSPA1A PE=1 SV=1 6.75 2844.6 - 1.68E+06 - - - 0.8869 - 3.805 0.321 - 851.2 1 2 1 0.0016 17 0 0 0 2.25E+07 1.94E+08 - - - 5.4943 1 221125_WJC_METTL3_EV_vs_WT_F06.17341.17341.4 6.07E-06 16/108 R.VIHLSNLPHSGYSDSAVLK.L "sp|P43243|MATR3_HUMAN,tr|B3KM87|B3KM87_HUMAN,tr|A8MXP9|A8MXP9_HUMAN,tr|D6RBK5|D6RBK5_HUMAN,tr|A0A0R4J2E8|A0A0R4J2E8_HUMAN,tr|H0Y8T4|H0Y8T4_HUMAN,tr|D6REM6|D6REM6_HUMAN" 7 2036.0691 1.18 85658 17341 4 2036.069149 510.0245 Matrin-3 OS=Homo sapiens OX=9606 GN=MATR3 PE=1 SV=2 6.89 2844.8 - 588073 - - - 0.029 - 3.323 0.473 - 244.5 1 2 0 0.0001 19 0 0 0 2.03E+07 1.72E+07 - - - 3.7492 1 221125_WJC_METTL3_EV_vs_WT_F06.17342.17342.2 2.96E-09 18/30 R.SNLC[160.03]ALC[160.03]IGDEQGENK.C "sp|P02788|TRFL_HUMAN,tr|E7EQB2|E7EQB2_HUMAN,tr|E7ER44|E7ER44_HUMAN" 3 1806.7876 999 85659 17342 2 1806.79045 904.4011 Lactotransferrin OS=Homo sapiens OX=9606 GN=LTF PE=1 SV=6 4.14 2844.9 - 653546 - - - 1.5508 - 3.164 0.687 - 941.8 1 2 0 0.0028 16 0 0 0 3.87E+07 0.00E+00 - - - 6.9461 1 221125_WJC_METTL3_EV_vs_WT_F06.17349.17349.3 3.09E-08 14/60 K.DTFEHDPSESIDEFNK.S "sp|Q9NYF8|BCLF1_HUMAN,tr|E9PKI6|E9PKI6_HUMAN,tr|A0A1W2PQ43|A0A1W2PQ43_HUMAN,tr|E9PK91|E9PK91_HUMAN,tr|E9PJA7|E9PJA7_HUMAN,tr|E9PK09|E9PK09_HUMAN,tr|E9PQN2|E9PQN2_HUMAN" 7 1908.8014 2.5 85663 17349 3 1908.802874 637.2744 Bcl-2-associated transcription factor 1 OS=Homo sapiens OX=9606 GN=BCLAF1 PE=1 SV=2 4.01 2845.8 - 1.09E+06 - - - 0.7895 - 2.857 0.68 - 324.9 1 2 0 0.0015 16 0 0 0 2.15E+09 8.59E+08 - - - 8.8145 0.9996 221125_WJC_METTL3_EV_vs_WT_F06.17350.17350.3 0.000429 Dec-48 R.VDQLSQQLEDLKK.G "sp|Q96KQ4|ASPP1_HUMAN,tr|A0A3B3ISJ2|A0A3B3ISJ2_HUMAN" 2 1542.8253 2.69 85664 17350 3 1542.83086 515.2824 Apoptosis-stimulating of p53 protein 1 OS=Homo sapiens OX=9606 GN=PPP1R13B PE=1 SV=3 4.56 2845.9 - 833045 - - - 3.5798 - 2.542 0.415 - 184.4 1 2 0 0.0055 13 0 0 0 1.33E+07 4.95E+06 - - - 5.6948 1 221125_WJC_METTL3_EV_vs_WT_F06.17356.17356.3 6.02E-07 17/44 K.TPELNLDQFHDK.T "sp|P27824|CALX_HUMAN,tr|A0A7P0T937|A0A7P0T937_HUMAN,tr|A0A7P0T840|A0A7P0T840_HUMAN,tr|D6RFL1|D6RFL1_HUMAN,tr|A0A7P0Z4H2|A0A7P0Z4H2_HUMAN,tr|A0A7P0TB65|A0A7P0TB65_HUMAN,tr|A0A7P0TAE9|A0A7P0TAE9_HUMAN,tr|D6RGY2|D6RGY2_HUMAN,tr|A0A7P0T8G1|A0A7P0T8G1_HUMAN,tr|A0A7P0Z4D6|A0A7P0Z4D6_HUMAN,tr|A0A7P0Z484|A0A7P0Z484_HUMAN,tr|A0A7P0TAR9|A0A7P0TAR9_HUMAN,tr|A0A7P0T9L0|A0A7P0T9L0_HUMAN" 13 1455.6994 1.23 85668 17356 3 1455.700221 486.2404 Calnexin OS=Homo sapiens OX=9606 GN=CANX PE=1 SV=2 4.53 2846.7 - 2.72E+06 - - - 0.5585 - 2.75 0.547 - 517.1 1 2 0 0.0008 12 0 0 0 4.60E+07 3.74E+07 - - - 7.4423 1 221125_WJC_METTL3_EV_vs_WT_F06.17357.17357.3 1.62E-08 19/52 K.HWPFQVINDGDKPK[136.11].V "sp|P0DMV8|HS71A_HUMAN,sp|P0DMV9|HS71B_HUMAN,tr|A0A0G2JIW1|A0A0G2JIW1_HUMAN" 3 1687.8562 - 85669 17357 3 1687.858674 563.626 Heat shock 70 kDa protein 1A OS=Homo sapiens OX=9606 GN=HSPA1A PE=1 SV=1 6.75 2846.8 - 2.18E+06 - - - 1.4717 - 3.021 0.453 - 608.9 1 2 0 0.0025 14 0 0 0 - - - - - 6.528 1 221125_WJC_METTL3_EV_vs_WT_F06.17360.17360.3 3.95E-07 13/60 K.DTFEHDPSESIDEFNK[136.11].S "sp|Q9NYF8|BCLF1_HUMAN,tr|E9PKI6|E9PKI6_HUMAN,tr|A0A1W2PQ43|A0A1W2PQ43_HUMAN,tr|E9PK91|E9PK91_HUMAN,tr|E9PJA7|E9PJA7_HUMAN,tr|E9PK09|E9PK09_HUMAN,tr|E9PQN2|E9PQN2_HUMAN" 7 1916.8156 2.5 85672 17360 3 1916.814954 639.9458 Bcl-2-associated transcription factor 1 OS=Homo sapiens OX=9606 GN=BCLAF1 PE=1 SV=2 4.01 2846.9 - 1.02E+06 - - - -0.3198 - 2.667 0.579 - 262.8 1 2 0 -0.0006 16 0 0 0 2.15E+09 8.57E+08 - - - 7.5121 0.9999 221125_WJC_METTL3_EV_vs_WT_F06.17361.17361.3 0.000107 17/92 K.AEAAPESQPPASEDLEVDPPVAAK.D sp|Q96T58|MINT_HUMAN 1 2417.1598 1.64 85673 17361 3 2417.166702 806.7272 Msx2-interacting protein OS=Homo sapiens OX=9606 GN=SPEN PE=1 SV=1 3.77 2847.1 - 775654 - - - 2.8492 - 3.112 0.544 - 156.7 1 2 0 0.0069 24 0 0 0 1.05E+07 6.38E+06 - - - 7.2399 0.9998 221125_WJC_METTL3_EV_vs_WT_F06.17362.17362.3 2.88E-05 Oct-76 R.FSSC[160.03]GGGGGSFGAGGGFGSR.S sp|P04264|K2C1_HUMAN 1 1764.7274 312.25 85674 17362 3 1764.725118 589.2498 "Keratin, type II cytoskeletal 1 OS=Homo sapiens OX=9606 GN=KRT1 PE=1 SV=6" 8.25 2847.2 - 549338 - - - -1.3107 - 2.223 0.367 - 98.9 1 2 0 -0.0023 20 0 0 0 3.68E+07 1.18E+05 - - - 4.5691 0.9972 221125_WJC_METTL3_EV_vs_WT_F06.17363.17363.4 0.00144 17/96 K.LDKAQIHDLVLVGGSTR.L "sp|P0DMV8|HS71A_HUMAN,sp|P0DMV9|HS71B_HUMAN,tr|V9GZ37|V9GZ37_HUMAN,tr|A0A0G2JIW1|A0A0G2JIW1_HUMAN" 4 1821.0108 0.12 85675 17363 4 1821.017729 456.26 Heat shock 70 kDa protein 1A OS=Homo sapiens OX=9606 GN=HSPA1A PE=1 SV=1 6.75 2847.3 - 448372 - - - 3.7792 - 2.793 0.398 - 211 1 2 1 0.0069 17 0 0 0 2.22E+07 1.79E+08 - - - 3.0449 0.9996 221125_WJC_METTL3_EV_vs_WT_F06.17364.17364.3 8.10E-05 Oct-52 K.K[136.11]PLR[166.11]VDLILENTSK[136.11].V "sp|Q9NZM5|NOP53_HUMAN,tr|M0QX73|M0QX73_HUMAN" 2 1650.9879 1.12 85676 17364 3 1650.986354 551.3366 Ribosome biogenesis protein NOP53 OS=Homo sapiens OX=9606 GN=NOP53 PE=1 SV=2 8.59 2847.5 - 262445 - - - -0.9219 - 1.946 0.448 - 97.4 1 2 1 -0.0015 14 0 0 0 4.01E+06 3.59E+06 - - - 5.3037 1 221125_WJC_METTL3_EV_vs_WT_F06.17374.17374.3 2.30E-12 33/88 K.LAQQQAAAAAAAAAAASQQGSAK.N "sp|Q9BZK7|TBL1R_HUMAN,tr|A0A1B0GUU2|A0A1B0GUU2_HUMAN,tr|C9IYU9|C9IYU9_HUMAN,tr|C9JCK0|C9JCK0_HUMAN,tr|A0A0D9SF63|A0A0D9SF63_HUMAN,tr|C9JBN1|C9JBN1_HUMAN,tr|C9JLJ1|C9JLJ1_HUMAN,tr|A0A0D9SF25|A0A0D9SF25_HUMAN" 8 2054.0505 1.97 85682 17374 3 2054.053635 685.6908 F-box-like\WD repeat-containing protein TBL1XR1 OS=Homo sapiens OX=9606 GN=TBL1XR1 PE=1 SV=1 8.75 2848.5 - 2.14E+06 - - - 1.536 - 5.396 0.65 - 1401.5 1 2 0 0.0032 23 0 0 0 1.55E+08 7.86E+07 - - - 9.7404 1 221125_WJC_METTL3_EV_vs_WT_F06.17376.17376.3 1.05E-08 22/64 R.RVPATTLYAHFEQANIK.T sp|Q7Z3B4|NUP54_HUMAN 1 1958.0374 2.21 85684 17376 3 1958.042695 653.6864 Nucleoporin p54 OS=Homo sapiens OX=9606 GN=NUP54 PE=1 SV=2 8.6 2848.8 - 1.03E+06 - - - 2.7063 - 3.724 0.508 - 798.3 1 2 0 0.0053 17 0 0 0 2.11E+08 9.58E+07 - - - 7.5238 0.9999 221125_WJC_METTL3_EV_vs_WT_F06.17377.17377.3 1.79E-10 20/88 R.SSIDSQASLSGPLSGGAPGAGAR.D sp|A6NKD9|CC85C_HUMAN 1 2042.0029 1.2 85685 17377 3 2042.010303 681.6749 Coiled-coil domain-containing protein 85C OS=Homo sapiens OX=9606 GN=CCDC85C PE=1 SV=1 5.55 2848.9 - 607834 - - - 3.6445 - 3.661 0.557 - 380.7 1 2 0 0.0074 23 0 0 0 2.00E+07 1.66E+07 - - - 7.7924 1 221125_WJC_METTL3_EV_vs_WT_F06.17384.17384.3 3.69E-06 19/72 K.QITSYGETC[160.03]PGLEQYAIK[136.11]K[136.11].F sp|P50990|TCPQ_HUMAN 1 2201.1009 0.38 85690 17384 3 2201.100597 734.7076 T-complex protein 1 subunit theta OS=Homo sapiens OX=9606 GN=CCT8 PE=1 SV=4 6.13 2849.7 - 4.32E+06 - - - -0.1467 - 3.584 0.575 - 340.8 1 2 0 -0.0003 19 0 0 0 2.67E+08 6.98E+08 - - - 8.0867 0.9998 221125_WJC_METTL3_EV_vs_WT_F06.17385.17385.3 0.000325 15/76 K.TAAAAADVNGFKPLSGNELK.N tr|D6RI06|D6RI06_HUMAN 1 1973.0218 9.4 85691 17385 3 1973.021041 658.6812 Ubiquitinyl hydrolase 1 (Fragment) OS=Homo sapiens OX=9606 GN=OTUD4 PE=1 SV=1 5.73 2849.8 - 679980 - - - -0.3872 - 2.286 0.38 - 179.4 1 2 0 -0.0008 20 0 0 0 1.79E+07 1.90E+06 - - - 4.7823 1 221125_WJC_METTL3_EV_vs_WT_F06.17386.17386.2 1.06E-11 18/30 K.DTFEHDPSESIDEFNK.S "sp|Q9NYF8|BCLF1_HUMAN,tr|E9PKI6|E9PKI6_HUMAN,tr|A0A1W2PQ43|A0A1W2PQ43_HUMAN,tr|E9PK91|E9PK91_HUMAN,tr|E9PJA7|E9PJA7_HUMAN,tr|E9PK09|E9PK09_HUMAN,tr|E9PQN2|E9PQN2_HUMAN" 7 1908.8014 2.8 85692 17386 2 1908.802589 955.408 Bcl-2-associated transcription factor 1 OS=Homo sapiens OX=9606 GN=BCLAF1 PE=1 SV=2 4.01 2849.9 - 538059 - - - 0.6402 - 3.594 0.727 - 978.3 1 2 0 0.0012 16 0 0 0 1.62E+08 5.78E+07 - - - 7.5554 0.9997 221125_WJC_METTL3_EV_vs_WT_F06.17388.17388.2 1.17E-08 Nov-32 K.VTFFEPGSGDENGTSNK.E "sp|O95793|STAU1_HUMAN,tr|Q5JW30|Q5JW30_HUMAN" 2 1784.7853 5.23 85694 17388 2 1784.79038 893.3999 Double-stranded RNA-binding protein Staufen homolog 1 OS=Homo sapiens OX=9606 GN=STAU1 PE=1 SV=2 4.14 2850.2 - 264390 - - - 2.8334 - 1.979 0.666 - 194.1 1 2 0 0.0051 17 0 0 0 1.21E+07 2.31E+06 - - - 5.6367 1 221125_WJC_METTL3_EV_vs_WT_F06.17391.17391.3 1.03E-07 16/72 K.QITSYGETC[160.03]PGLEQYAIKK.F sp|P50990|TCPQ_HUMAN 1 2185.0725 0.38 85695 17391 3 2185.075726 729.3648 T-complex protein 1 subunit theta OS=Homo sapiens OX=9606 GN=CCT8 PE=1 SV=4 6.13 2850.6 - 2.26E+06 - - - 1.4672 - 2.878 0.541 - 230.2 1 2 0 0.0032 19 0 0 0 2.67E+08 6.98E+08 - - - 7.1678 0.9999 221125_WJC_METTL3_EV_vs_WT_F06.17395.17395.4 1.09E-05 11/108 R.GLLQDDAHPTLVTYADHSK[136.11].L "sp|Q86U44|MTA70_HUMAN,tr|F5H6D8|F5H6D8_HUMAN,tr|H0YFV6|H0YFV6_HUMAN,tr|B4DTN4|B4DTN4_HUMAN" 4 2088.0367 0.03 85698 17395 4 2088.033536 523.0165 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 5.13 2851.1 - 2.12E+07 - - - -1.5311 - 2.629 0.457 - 114.6 1 2 0 -0.0032 19 0 0 0 4.30E+07 1.42E+09 - - - 3.5298 1 221125_WJC_METTL3_EV_vs_WT_F06.17397.17397.2 7.80E-06 15/34 K.SSGAGSTSDAYTVIQVGR.E "sp|Q9BXF6|RFIP5_HUMAN,tr|A0A1B0GTL5|A0A1B0GTL5_HUMAN" 2 1754.8435 1.93 85699 17397 2 1754.842653 878.429 Rab11 family-interacting protein 5 OS=Homo sapiens OX=9606 GN=RAB11FIP5 PE=1 SV=1 5.55 2851.3 - 382586 - - - -0.4861 - 3.324 0.616 - 652.7 1 2 0 -0.0009 18 0 0 0 8.07E+06 4.17E+06 - - - 6.5436 1 221125_WJC_METTL3_EV_vs_WT_F06.17404.17404.2 2.91E-11 17/30 K.DTFEHDPSESIDEFNK[136.11].S "sp|Q9NYF8|BCLF1_HUMAN,tr|E9PKI6|E9PKI6_HUMAN,tr|A0A1W2PQ43|A0A1W2PQ43_HUMAN,tr|E9PK91|E9PK91_HUMAN,tr|E9PJA7|E9PJA7_HUMAN,tr|E9PK09|E9PK09_HUMAN,tr|E9PQN2|E9PQN2_HUMAN" 7 1916.8156 2.8 85704 17404 2 1916.814492 959.4151 Bcl-2-associated transcription factor 1 OS=Homo sapiens OX=9606 GN=BCLAF1 PE=1 SV=2 4.01 2852.2 - 640032 - - - -0.5608 - 3.413 0.705 - 803 1 2 0 -0.0011 16 0 0 0 1.62E+08 5.78E+07 - - - 7.2659 1 221125_WJC_METTL3_EV_vs_WT_F06.17407.17407.2 2.06E-14 16/38 R.FSSC[160.03]GGGGGSFGAGGGFGSR.S sp|P04264|K2C1_HUMAN 1 1764.7274 999 85706 17407 2 1764.728027 883.371 "Keratin, type II cytoskeletal 1 OS=Homo sapiens OX=9606 GN=KRT1 PE=1 SV=6" 8.25 2852.5 - 1.34E+06 - - - 0.3377 - 3.848 0.757 - 837.4 1 2 0 0.0006 20 0 0 0 5.59E+07 0.00E+00 - - - 7.945 1 221125_WJC_METTL3_EV_vs_WT_F06.17411.17411.3 3.89E-16 23/96 K.LVQDVANNTNEEAGDGTTTATVLAR.S "sp|P10809|CH60_HUMAN,tr|C9JL25|C9JL25_HUMAN,tr|A0A7I2V2X6|A0A7I2V2X6_HUMAN,tr|A0A7I2YQK6|A0A7I2YQK6_HUMAN,tr|A0A7I2V599|A0A7I2V599_HUMAN,tr|E7EXB4|E7EXB4_HUMAN,tr|A0A7I2YQ71|A0A7I2YQ71_HUMAN,tr|E7ESH4|E7ESH4_HUMAN,tr|A0A7I2V5M1|A0A7I2V5M1_HUMAN,tr|A0A7I2V5K3|A0A7I2V5K3_HUMAN,tr|A0A7I2V369|A0A7I2V369_HUMAN" 11 2559.2413 1.38 85708 17411 3 2559.238144 854.0877 "60 kDa heat shock protein, mitochondrial OS=Homo sapiens OX=9606 GN=HSPD1 PE=1 SV=2" 3.92 2852.9 - 2.94E+06 - - - -1.2148 - 4.132 0.671 - 693.4 1 2 0 -0.0031 25 0 0 0 1.42E+08 1.02E+08 - - - 9.2842 1 221125_WJC_METTL3_EV_vs_WT_F06.17413.17413.3 7.64E-10 35/88 K.LAQQQAAAAAAAAAAASQQGSAK[136.11].N "sp|Q9BZK7|TBL1R_HUMAN,tr|A0A1B0GUU2|A0A1B0GUU2_HUMAN,tr|C9IYU9|C9IYU9_HUMAN,tr|C9JCK0|C9JCK0_HUMAN,tr|A0A0D9SF63|A0A0D9SF63_HUMAN,tr|C9JBN1|C9JBN1_HUMAN,tr|C9JLJ1|C9JLJ1_HUMAN,tr|A0A0D9SF25|A0A0D9SF25_HUMAN" 8 2062.0647 1.97 85710 17413 3 2062.066801 688.3622 F-box-like\WD repeat-containing protein TBL1XR1 OS=Homo sapiens OX=9606 GN=TBL1XR1 PE=1 SV=1 8.75 2853.1 - 4.58E+06 - - - 1.0286 - 5.693 0.594 - 2107 1 2 0 0.0021 23 0 0 0 1.55E+08 7.86E+07 - - - 9.2421 0.9999 221125_WJC_METTL3_EV_vs_WT_F06.17414.17414.4 0.00017 24/102 R.EALLSSAVDHGSDEVK[136.11]FR[166.11].Q "sp|P78371|TCPB_HUMAN,tr|F8VQ14|F8VQ14_HUMAN,tr|F5GWF6|F5GWF6_HUMAN" 3 1976.9922 0.45 85711 17414 4 1976.988277 495.2553 T-complex protein 1 subunit beta OS=Homo sapiens OX=9606 GN=CCT2 PE=1 SV=4 4.75 2853.2 - 834037 - - - -2.0046 - 4.638 0.529 - 668.3 1 2 1 -0.004 18 0 0 0 1.27E+07 2.80E+07 - - - 4.3549 1 221125_WJC_METTL3_EV_vs_WT_F06.17418.17418.3 3.47E-09 18/80 R.QINTLNHGEVVC[160.03]AVTISNPTR.H "sp|Q04727|TLE4_HUMAN,sp|Q04724|TLE1_HUMAN,tr|H7C4E4|H7C4E4_HUMAN" 3 2322.175 1.31 85713 17418 3 2322.176512 775.0656 Transducin-like enhancer protein 4 OS=Homo sapiens OX=9606 GN=TLE4 PE=1 SV=3 6.74 2853.7 - 728274 - - - 0.6391 - 3.182 0.482 - 252 1 2 0 0.0015 21 0 0 0 1.61E+07 1.23E+07 - - - 6.6885 0.9999 221125_WJC_METTL3_EV_vs_WT_F06.17421.17421.4 1.10E-07 23/120 K.VLSVETPLSIQAHPNKELAEK.L "sp|P34949|MPI_HUMAN,tr|H3BPB8|H3BPB8_HUMAN,tr|H3BP57|H3BP57_HUMAN,tr|H3BT48|H3BT48_HUMAN,tr|H3BPU7|H3BPU7_HUMAN,tr|H3BUZ9|H3BUZ9_HUMAN,tr|H3BT46|H3BT46_HUMAN,tr|H3BPM5|H3BPM5_HUMAN,tr|B4DYB8|B4DYB8_HUMAN,tr|H3BPP3|H3BPP3_HUMAN,tr|H3BN01|H3BN01_HUMAN,tr|F5GX71|F5GX71_HUMAN,tr|H3BMZ9|H3BMZ9_HUMAN,tr|H3BNY8|H3BNY8_HUMAN" 14 2302.2533 1.64 85716 17421 4 2302.251842 576.5706 Mannose-6-phosphate isomerase OS=Homo sapiens OX=9606 GN=MPI PE=1 SV=2 5.5 2854 - 902693 - - - -0.6168 - 3.788 0.487 - 419.2 1 2 1 -0.0014 21 0 0 0 1.01E+08 6.17E+07 - - - 3.9048 1 221125_WJC_METTL3_EV_vs_WT_F06.17427.17427.3 1.44E-06 18/72 R.GLLQDDAHPTLVTYADHSK[136.11].L "sp|Q86U44|MTA70_HUMAN,tr|F5H6D8|F5H6D8_HUMAN,tr|H0YFV6|H0YFV6_HUMAN,tr|B4DTN4|B4DTN4_HUMAN" 4 2088.0367 0.01 85720 17427 3 2088.036316 697.0195 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 5.13 2854.8 - 7.44E+06 - - - -0.1997 - 3.208 0.628 - 392.9 1 2 0 -0.0004 19 0 0 0 2.80E+06 4.12E+08 - - - 8.4052 0.9994 221125_WJC_METTL3_EV_vs_WT_F06.17430.17430.4 0.000578 19/120 K.VLSVETPLSIQAHPNK[136.11]ELAEK[136.11].L "sp|P34949|MPI_HUMAN,tr|H3BPB8|H3BPB8_HUMAN,tr|H3BP57|H3BP57_HUMAN,tr|H3BT48|H3BT48_HUMAN,tr|H3BPU7|H3BPU7_HUMAN,tr|H3BUZ9|H3BUZ9_HUMAN,tr|H3BT46|H3BT46_HUMAN,tr|H3BPM5|H3BPM5_HUMAN,tr|B4DYB8|B4DYB8_HUMAN,tr|H3BPP3|H3BPP3_HUMAN,tr|H3BN01|H3BN01_HUMAN,tr|F5GX71|F5GX71_HUMAN,tr|H3BMZ9|H3BMZ9_HUMAN,tr|H3BNY8|H3BNY8_HUMAN" 14 2318.2817 1.64 85723 17430 4 2318.283362 580.5777 Mannose-6-phosphate isomerase OS=Homo sapiens OX=9606 GN=MPI PE=1 SV=2 5.5 2855.1 - 1.23E+06 - - - 0.7333 - 3.766 0.378 - 187.6 1 2 1 0.0017 21 0 0 0 1.01E+08 6.17E+07 - - - 2.9541 1 221125_WJC_METTL3_EV_vs_WT_F06.17438.17438.3 8.46E-10 22/96 K.LVQDVANNTNEEAGDGTTTATVLAR[166.11].S "sp|P10809|CH60_HUMAN,tr|C9JL25|C9JL25_HUMAN,tr|A0A7I2V2X6|A0A7I2V2X6_HUMAN,tr|A0A7I2YQK6|A0A7I2YQK6_HUMAN,tr|A0A7I2V599|A0A7I2V599_HUMAN,tr|E7EXB4|E7EXB4_HUMAN,tr|A0A7I2YQ71|A0A7I2YQ71_HUMAN,tr|E7ESH4|E7ESH4_HUMAN,tr|A0A7I2V5M1|A0A7I2V5M1_HUMAN,tr|A0A7I2V5K3|A0A7I2V5K3_HUMAN,tr|A0A7I2V369|A0A7I2V369_HUMAN" 11 2569.2495 1.34 85730 17438 3 2570.247278 857.4238 "60 kDa heat shock protein, mitochondrial OS=Homo sapiens OX=9606 GN=HSPD1 PE=1 SV=2" 3.92 2856.1 - 2.43E+06 - - - 388.3449 - 4.044 0.668 - 682.7 1 2 0 0.9978 25 0 0 0 1.63E+08 1.21E+08 - - - 8.9257 1 221125_WJC_METTL3_EV_vs_WT_F06.17441.17441.3 1.91E-11 20/80 K.LQVVLNESNADTYAGRPLPSK.A "sp|A6NHR9|SMHD1_HUMAN,tr|J3KTL8|J3KTL8_HUMAN,tr|J3QSH1|J3QSH1_HUMAN" 3 2271.1859 1.95 85733 17441 3 2271.191639 758.0692 Structural maintenance of chromosomes flexible hinge domain-containing protein 1 OS=Homo sapiens OX=9606 GN=SMCHD1 PE=1 SV=2 6.07 2856.4 - 1.27E+06 - - - 2.5225 - 4.506 0.662 - 280.2 1 2 0 0.0057 21 0 0 0 1.81E+07 9.30E+06 - - - 9.5282 1 221125_WJC_METTL3_EV_vs_WT_F06.17443.17443.4 3.87E-07 16/78 K.HWPFQVINDGDK[136.11]PK[136.11].V "sp|P0DMV8|HS71A_HUMAN,sp|P0DMV9|HS71B_HUMAN,tr|A0A0G2JIW1|A0A0G2JIW1_HUMAN" 3 1695.8704 0.15 85734 17443 4 1695.869201 424.9749 Heat shock 70 kDa protein 1A OS=Homo sapiens OX=9606 GN=HSPA1A PE=1 SV=1 6.75 2856.6 - 4.23E+07 - - - -0.7011 - 2.63 0.605 - 180.6 1 2 0 -0.0012 14 0 0 0 2.39E+08 1.59E+09 - - - 4.8435 0.9999 221125_WJC_METTL3_EV_vs_WT_F06.17446.17446.3 9.89E-06 15/64 R.ASDGGANIQLHAQQLLK.R "sp|Q9Y2K2|SIK3_HUMAN,tr|H7C3X8|H7C3X8_HUMAN,tr|H0Y4E8|H0Y4E8_HUMAN" 3 1762.9326 14.5 85736 17446 3 1762.935734 588.6515 Serine\threonine-protein kinase SIK3 OS=Homo sapiens OX=9606 GN=SIK3 PE=1 SV=4 6.79 2856.9 - 1.19E+06 - - - 1.78 - 2.54 0.475 - 176.2 1 2 0 0.0031 17 0 0 0 2.86E+07 1.97E+06 - - - 6.1898 1 221125_WJC_METTL3_EV_vs_WT_F06.17447.17447.3 8.12E-07 20/80 K.LQVVLNESNADTYAGR[166.11]PLPSK[136.11].A "sp|A6NHR9|SMHD1_HUMAN,tr|J3KTL8|J3KTL8_HUMAN,tr|J3QSH1|J3QSH1_HUMAN" 3 2289.2084 1.95 85737 17447 3 2289.20506 764.0767 Structural maintenance of chromosomes flexible hinge domain-containing protein 1 OS=Homo sapiens OX=9606 GN=SMCHD1 PE=1 SV=2 6.07 2857.1 - 930585 - - - -1.4503 - 3.699 0.574 - 340.5 1 2 0 -0.0033 21 0 0 0 1.81E+07 9.30E+06 - - - 8.0746 1 221125_WJC_METTL3_EV_vs_WT_F06.17451.17451.3 2.20E-07 18/52 K.HWPFQVINDGDK[136.11]PK[136.11].V "sp|P0DMV8|HS71A_HUMAN,sp|P0DMV9|HS71B_HUMAN,tr|A0A0G2JIW1|A0A0G2JIW1_HUMAN" 3 1695.8704 0.14 85739 17451 3 1695.870129 566.2974 Heat shock 70 kDa protein 1A OS=Homo sapiens OX=9606 GN=HSPA1A PE=1 SV=1 6.75 2857.6 - 1.61E+08 - - - -0.1539 - 3.032 0.605 - 552 1 2 0 -0.0003 14 0 0 0 9.21E+08 6.77E+09 - - - 8.2329 1 221125_WJC_METTL3_EV_vs_WT_F06.17454.17454.3 9.15E-10 21/76 K.MIQDGK[136.11]GDVTITNDGATILK[136.11].Q sp|P50991|TCPD_HUMAN 1 2105.1009 0.01 85742 17454 3 2105.102441 702.7076 T-complex protein 1 subunit delta OS=Homo sapiens OX=9606 GN=CCT4 PE=1 SV=4 4.43 2857.9 - 1.82E+06 - - - 0.7225 - 3.666 0.583 - 286.2 1 2 1 0.0015 20 0 0 0 1.57E+06 2.03E+08 - - - 8.1911 0.944 221125_WJC_METTL3_EV_vs_WT_F06.17456.17456.4 0.000429 17/108 H.MGDFGSIHR[166.11]PGIVVDYQNK[136.11].S "sp|Q5BKZ1|ZN326_HUMAN,tr|A0A0A0MRN4|A0A0A0MRN4_HUMAN" 2 2150.0698 1.16 85744 17456 4 2150.072088 538.5247 DBIRD complex subunit ZNF326 OS=Homo sapiens OX=9606 GN=ZNF326 PE=1 SV=2 6.5 2858.1 - 877620 - - - 1.0744 - 2.085 0.332 - 115.4 1 1 0 0.0023 19 0 0 0 1.44E+07 1.24E+07 - - - 2.3636 0.9999 221125_WJC_METTL3_EV_vs_WT_F06.17461.17461.4 6.24E-06 15/90 R.NLNTSALQLEHEHLIK.L "sp|Q15643|TRIPB_HUMAN,tr|H0YJ97|H0YJ97_HUMAN" 2 1858.9901 1.36 85747 17461 4 1858.989684 465.7548 Thyroid receptor-interacting protein 11 OS=Homo sapiens OX=9606 GN=TRIP11 PE=1 SV=3 6 2858.7 - 2.25E+06 - - - -0.2297 - 3.245 0.42 - 188.6 1 2 0 -0.0004 16 0 0 0 1.10E+08 8.09E+07 - - - 3.2962 1 221125_WJC_METTL3_EV_vs_WT_F06.17467.17467.3 4.65E-10 18/64 K.AQLDQTGQHLFC[160.03]VC[160.03]GTR.V sp|Q12788|TBL3_HUMAN 1 1989.9149 0.91 85749 17467 3 1989.91212 664.3122 Transducin beta-like protein 3 OS=Homo sapiens OX=9606 GN=TBL3 PE=1 SV=2 6.77 2859.6 - 765934 - - - -1.4046 - 3.37 0.623 - 438.4 1 2 0 -0.0028 17 0 0 0 3.27E+07 3.60E+07 - - - 8.5543 1 221125_WJC_METTL3_EV_vs_WT_F06.17469.17469.3 1.34E-05 16/60 R.NLNTSALQLEHEHLIK.L "sp|Q15643|TRIPB_HUMAN,tr|H0YJ97|H0YJ97_HUMAN" 2 1858.9901 1.3 85750 17469 3 1858.989662 620.6706 Thyroid receptor-interacting protein 11 OS=Homo sapiens OX=9606 GN=TRIP11 PE=1 SV=3 6 2859.8 - 1.18E+06 - - - -0.2415 - 2.595 0.474 - 208.8 1 2 0 -0.0004 16 0 0 0 4.64E+07 3.57E+07 - - - 6.2713 0.9999 221125_WJC_METTL3_EV_vs_WT_F06.17471.17471.3 4.04E-09 19/80 K.VLSVETPLSIQAHPNKELAEK.L "sp|P34949|MPI_HUMAN,tr|H3BPB8|H3BPB8_HUMAN,tr|H3BP57|H3BP57_HUMAN,tr|H3BT48|H3BT48_HUMAN,tr|H3BPU7|H3BPU7_HUMAN,tr|H3BUZ9|H3BUZ9_HUMAN,tr|H3BT46|H3BT46_HUMAN,tr|H3BPM5|H3BPM5_HUMAN,tr|B4DYB8|B4DYB8_HUMAN,tr|H3BPP3|H3BPP3_HUMAN,tr|H3BN01|H3BN01_HUMAN,tr|F5GX71|F5GX71_HUMAN,tr|H3BMZ9|H3BMZ9_HUMAN,tr|H3BNY8|H3BNY8_HUMAN" 14 2302.2533 1.82 85752 17471 3 2302.253887 768.425 Mannose-6-phosphate isomerase OS=Homo sapiens OX=9606 GN=MPI PE=1 SV=2 5.5 2860 - 1.03E+06 - - - 0.2715 - 3.614 0.521 - 356.1 1 2 1 0.0006 21 0 0 0 2.21E+07 1.21E+07 - - - 7.4287 1 221125_WJC_METTL3_EV_vs_WT_F06.17476.17476.4 0.000116 16/96 R.RVPATTLYAHFEQANIK.T sp|Q7Z3B4|NUP54_HUMAN 1 1958.0374 2.63 85754 17476 4 1958.037222 490.5166 Nucleoporin p54 OS=Homo sapiens OX=9606 GN=NUP54 PE=1 SV=2 8.6 2860.6 - 2.82E+06 - - - -0.0889 - 2.662 0.469 - 242.7 1 2 0 -0.0002 17 0 0 0 1.57E+08 6.00E+07 - - - 3.6481 0.9936 221125_WJC_METTL3_EV_vs_WT_F06.17477.17477.3 0.351 Oct-44 R.NSDSILEAIQKK.L "sp|P19404|NDUV2_HUMAN,tr|E7EPT4|E7EPT4_HUMAN" 2 1344.7249 1.82 85755 17477 3 1344.72667 449.2489 "NADH dehydrogenase [ubiquinone] flavoprotein 2, mitochondrial OS=Homo sapiens OX=9606 GN=NDUFV2 PE=1 SV=2" 6.07 2860.8 - 344088 - - - 1.32 - 1.611 0.214 - 88.7 1 2 0 0.0018 12 0 0 0 1.63E+07 8.92E+06 - - - 2.2472 1 221125_WJC_METTL3_EV_vs_WT_F06.17480.17480.3 1.02E-07 25/68 R.ATDSKEPPGELC[160.03]PDVLYR.T "sp|Q9BUK6|MSTO1_HUMAN,tr|A0A3B3IUD2|A0A3B3IUD2_HUMAN" 2 2045.9728 2.03 85758 17480 3 2045.973463 682.9982 Protein misato homolog 1 OS=Homo sapiens OX=9606 GN=MSTO1 PE=1 SV=1 4.32 2861.1 - 1.77E+06 - - - 0.3211 - 3.984 0.589 - 677.9 1 2 1 0.0007 18 0 0 0 5.80E+07 2.86E+07 - - - 8.5486 1 221125_WJC_METTL3_EV_vs_WT_F06.17483.17483.4 5.36E-10 18/102 K.FAASGGFLHHMAGLSSSK[136.11].L "sp|Q9BY77|PDIP3_HUMAN,tr|F6VRR5|F6VRR5_HUMAN,tr|F8WCX5|F8WCX5_HUMAN,tr|Q8WUT1|Q8WUT1_HUMAN" 4 1811.8868 1.39 85761 17483 4 1811.885345 453.979 Polymerase delta-interacting protein 3 OS=Homo sapiens OX=9606 GN=POLDIP3 PE=1 SV=2 8.76 2861.4 - 594809 - - - -0.824 - 3.809 0.515 - 268.9 1 2 0 -0.0015 18 0 0 0 8.75E+08 6.32E+08 - - - 4.1663 1 221125_WJC_METTL3_EV_vs_WT_F06.17486.17486.3 1.08E-09 15/52 K.HWPFQVINDGDKPK.V "sp|P0DMV8|HS71A_HUMAN,sp|P0DMV9|HS71B_HUMAN,tr|A0A0G2JIW1|A0A0G2JIW1_HUMAN" 3 1679.842 0.14 85762 17486 3 1679.841587 560.9546 Heat shock 70 kDa protein 1A OS=Homo sapiens OX=9606 GN=HSPA1A PE=1 SV=1 6.75 2861.8 - 2.12E+07 - - - -0.2399 - 3.197 0.543 - 377.8 1 2 0 -0.0004 14 0 0 0 9.23E+08 6.78E+09 - - - 7.6824 0.9991 221125_WJC_METTL3_EV_vs_WT_F06.17488.17488.3 0.000847 Nov-60 R.NLNTSALQLEHEHLIK[136.11].L "sp|Q15643|TRIPB_HUMAN,tr|H0YJ97|H0YJ97_HUMAN" 2 1867.0043 1.3 85764 17488 3 1867.001028 623.342 Thyroid receptor-interacting protein 11 OS=Homo sapiens OX=9606 GN=TRIP11 PE=1 SV=3 6 2862 - 1.46E+06 - - - -1.7584 - 2.087 0.296 - 81 1 2 0 -0.0033 16 0 0 0 4.63E+07 3.57E+07 - - - 3.727 0.9997 221125_WJC_METTL3_EV_vs_WT_F06.17489.17489.3 0.000645 Oct-80 R.GADDAMESSKPGPVQVVLVQK.D "sp|Q6DD88|ATLA3_HUMAN,tr|F5GWF8|F5GWF8_HUMAN" 2 2154.0991 1.55 85765 17489 3 2154.103662 719.0403 Atlastin-3 OS=Homo sapiens OX=9606 GN=ATL3 PE=1 SV=1 4.56 2862.1 - 1.24E+06 - - - 2.1322 - 1.94 0.423 - 66.9 1 2 0 0.0046 21 0 0 0 2.29E+07 1.48E+07 - - - 4.8435 1 221125_WJC_METTL3_EV_vs_WT_F06.17491.17491.2 1.27E-11 19/34 K.YVHYEIDAC[160.03]MDSEAPGSK[136.11].D "sp|Q86U44|MTA70_HUMAN,tr|H0YFV6|H0YFV6_HUMAN" 2 2078.8805 0.001 85767 17491 2 2078.872118 1040.4475 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 4.31 2862.4 - 391932 - - - -4.0281 - 4.036 0.742 - 725.5 1 2 0 -0.0084 18 0 0 0 0.00E+00 9.41E+06 - - - 7.9491 1 221125_WJC_METTL3_EV_vs_WT_F06.17494.17494.4 1.19E-06 22/102 K.FAASGGFLHHMAGLSSSK.L "sp|Q9BY77|PDIP3_HUMAN,tr|F6VRR5|F6VRR5_HUMAN,tr|F8WCX5|F8WCX5_HUMAN,tr|Q8WUT1|Q8WUT1_HUMAN" 4 1803.8726 1.39 85768 17494 4 1803.870719 451.9754 Polymerase delta-interacting protein 3 OS=Homo sapiens OX=9606 GN=POLDIP3 PE=1 SV=2 8.76 2862.7 - 1.99E+06 - - - -1.0638 - 2.861 0.48 - 312.2 1 2 0 -0.0019 18 0 0 0 8.82E+08 6.36E+08 - - - 3.7635 1 221125_WJC_METTL3_EV_vs_WT_F06.17501.17501.3 2.15E-08 14/68 K.NTAPDNGPILLQAQTTQR.C "sp|Q12788|TBL3_HUMAN,tr|J3KNP2|J3KNP2_HUMAN,tr|A0A087WYP7|A0A087WYP7_HUMAN" 3 1936.9967 1.03 85772 17501 3 1937.000435 646.6728 Transducin beta-like protein 3 OS=Homo sapiens OX=9606 GN=TBL3 PE=1 SV=2 5.84 2863.5 - 891289 - - - 1.9525 - 2.927 0.578 - 285.5 1 2 0 0.0038 18 0 0 0 4.97E+07 4.83E+07 - - - 7.6574 1 221125_WJC_METTL3_EV_vs_WT_F06.17506.17506.3 2.95E-09 13/52 K.HMNLILC[160.03]DC[160.03]DEFR[166.11]K[136.11].L "sp|P63162|RSMN_HUMAN,sp|P14678|RSMB_HUMAN,tr|J3KRY3|J3KRY3_HUMAN,tr|J3QLE5|J3QLE5_HUMAN,tr|S4R3P3|S4R3P3_HUMAN" 5 1867.8498 1.71 85775 17506 3 1867.845988 623.6239 Small nuclear ribonucleoprotein-associated protein N OS=Homo sapiens OX=9606 GN=SNRPN PE=1 SV=1 5.38 2864.1 - 1.49E+06 - - - -2.0489 - 2.847 0.608 - 240.8 1 2 0 -0.0038 14 0 0 0 6.32E+07 3.70E+07 - - - 8.098 1 221125_WJC_METTL3_EV_vs_WT_F06.17508.17508.2 1.78E-14 17/30 K.QGQISSNYDDAMQFSK.K sp|Q9Y2X9|ZN281_HUMAN 1 1817.789 5.25 85777 17508 2 1817.787891 909.9018 Zinc finger protein 281 OS=Homo sapiens OX=9606 GN=ZNF281 PE=1 SV=1 4.21 2864.3 - 1.38E+06 - - - -0.6255 - 3.435 0.682 - 881.5 1 2 0 -0.0011 16 0 0 0 2.66E+07 5.07E+06 - - - 7.1118 0.9991 221125_WJC_METTL3_EV_vs_WT_F06.17509.17509.4 0.0034 14/78 K.DTSLYRPALEELRR.Q "sp|Q13200|PSMD2_HUMAN,tr|C9JPC0|C9JPC0_HUMAN,tr|H7C2Q3|H7C2Q3_HUMAN" 3 1717.9111 0.51 85778 17509 4 1717.910512 430.4851 26S proteasome non-ATPase regulatory subunit 2 OS=Homo sapiens OX=9606 GN=PSMD2 PE=1 SV=3 6.18 2864.4 - 1.18E+06 - - - -0.3609 - 2.118 0.297 - 167.1 1 2 0 -0.0006 14 0 0 0 3.51E+07 6.94E+07 - - - 2.084 0.9999 221125_WJC_METTL3_EV_vs_WT_F06.17510.17510.3 0.00227 18/52 K.DTSLYRPALEELRR.Q "sp|Q13200|PSMD2_HUMAN,tr|C9JPC0|C9JPC0_HUMAN,tr|H7C2Q3|H7C2Q3_HUMAN" 3 1717.9111 0.45 85779 17510 3 1717.90858 573.6443 26S proteasome non-ATPase regulatory subunit 2 OS=Homo sapiens OX=9606 GN=PSMD2 PE=1 SV=3 6.18 2864.5 - 577342 - - - -1.4855 - 2.918 0.416 - 336 1 2 0 -0.0026 14 0 0 0 2.50E+07 5.51E+07 - - - 6.0232 1 221125_WJC_METTL3_EV_vs_WT_F06.17513.17513.2 2.35E-09 17/26 K.HWPFQVINDGDK[136.11]PK[136.11].V "sp|P0DMV8|HS71A_HUMAN,sp|P0DMV9|HS71B_HUMAN,tr|A0A0G2JIW1|A0A0G2JIW1_HUMAN" 3 1695.8704 0.05 85781 17513 2 1695.870035 848.9425 Heat shock 70 kDa protein 1A OS=Homo sapiens OX=9606 GN=HSPA1A PE=1 SV=1 6.75 2864.9 - 2.41E+06 - - - -0.2093 - 3.008 0.57 - 583 1 2 0 -0.0004 14 0 0 0 1.85E+07 4.01E+08 - - - 6.0145 1 221125_WJC_METTL3_EV_vs_WT_F06.17515.17515.3 6.12E-11 18/68 K.FAASGGFLHHMAGLSSSK.L "sp|Q9BY77|PDIP3_HUMAN,tr|F6VRR5|F6VRR5_HUMAN,tr|F8WCX5|F8WCX5_HUMAN,tr|Q8WUT1|Q8WUT1_HUMAN" 4 1803.8726 1.4 85782 17515 3 1803.874701 602.2982 Polymerase delta-interacting protein 3 OS=Homo sapiens OX=9606 GN=POLDIP3 PE=1 SV=2 8.76 2865.1 - 4.62E+06 - - - 1.1437 - 3.383 0.59 - 386 1 2 0 0.0021 18 0 0 0 8.85E+08 6.32E+08 - - - 8.1522 1 221125_WJC_METTL3_EV_vs_WT_F06.17521.17521.3 8.20E-08 15/68 K.NTAPDNGPILLQAQTTQR[166.11].C "sp|Q12788|TBL3_HUMAN,tr|J3KNP2|J3KNP2_HUMAN,tr|A0A087WYP7|A0A087WYP7_HUMAN" 3 1947.0049 0.99 85786 17521 3 1947.003562 650.0089 Transducin beta-like protein 3 OS=Homo sapiens OX=9606 GN=TBL3 PE=1 SV=2 5.84 2865.8 - 1.44E+06 - - - -0.699 - 2.884 0.596 - 267.9 1 2 0 -0.0014 18 0 0 0 4.98E+07 5.02E+07 - - - 7.8219 0.9979 221125_WJC_METTL3_EV_vs_WT_F06.17522.17522.3 1.01E-06 17/52 K.LGKDAVEDLESVGK.G sp|P81605|DCD_HUMAN 1 1458.7566 16.43 85787 17522 3 1458.763679 487.2595 Dermcidin OS=Homo sapiens OX=9606 GN=DCD PE=1 SV=2 4.32 2865.9 - 1.16E+06 - - - 4.8603 - 2.773 0.469 - 235.1 1 2 1 0.0071 14 0 0 0 6.11E+07 3.72E+06 - - - 6.4774 1 221125_WJC_METTL3_EV_vs_WT_F06.17525.17525.2 1.66E-11 16/34 K.NTAPDNGPILLQAQTTQR.C "sp|Q12788|TBL3_HUMAN,tr|J3KNP2|J3KNP2_HUMAN,tr|A0A087WYP7|A0A087WYP7_HUMAN" 3 1936.9967 1.41 85790 17525 2 1936.994437 969.5056 Transducin beta-like protein 3 OS=Homo sapiens OX=9606 GN=TBL3 PE=1 SV=2 5.84 2866.1 - 470115 - - - -1.144 - 3.245 0.728 - 950.6 1 2 0 -0.0022 18 0 0 0 1.21E+07 8.62E+06 - - - 7.3113 1 221125_WJC_METTL3_EV_vs_WT_F06.17526.17526.2 3.97E-11 14/36 N.SGTLPQSSAVGSAFTQDTR[166.11].S "sp|Q8ND56|LS14A_HUMAN,tr|A0A140TA76|A0A140TA76_HUMAN,tr|K7EMZ9|K7EMZ9_HUMAN" 3 1918.926 0.99 85791 17526 2 1918.926571 960.4703 Protein LSM14 homolog A OS=Homo sapiens OX=9606 GN=LSM14A PE=1 SV=3 5.55 2866.3 - 331574 - - - 0.2955 - 2.992 0.669 - 596.3 1 1 0 0.0006 19 0 0 0 4.61E+06 4.64E+06 - - - 6.6765 0.9999 221125_WJC_METTL3_EV_vs_WT_F06.17533.17533.4 1.29E-05 15/90 R.NLNTSALQLEHEHLIK[136.11].L "sp|Q15643|TRIPB_HUMAN,tr|H0YJ97|H0YJ97_HUMAN" 2 1867.0043 1.35 85795 17533 4 1867.003118 467.7584 Thyroid receptor-interacting protein 11 OS=Homo sapiens OX=9606 GN=TRIP11 PE=1 SV=3 6 2867 - 2.43E+06 - - - -0.639 - 2.61 0.399 - 205.5 1 2 0 -0.0012 16 0 0 0 1.09E+08 8.08E+07 - - - 3.0365 0.9999 221125_WJC_METTL3_EV_vs_WT_F06.17534.17534.3 7.58E-06 14/60 R.DSISLTIVGTQGESHK.Q sp|O75342|LX12B_HUMAN 1 1670.8475 6.59 85796 17534 3 1670.848403 557.9565 "Arachidonate 12-lipoxygenase, 12R-type OS=Homo sapiens OX=9606 GN=ALOX12B PE=1 SV=1" 5.32 2867.1 - 1.17E+06 - - - 0.5231 - 2.62 0.415 - 184.9 1 2 0 0.0009 16 0 0 0 2.18E+07 3.31E+06 - - - 5.638 1 221125_WJC_METTL3_EV_vs_WT_F06.17537.17537.4 4.27E-09 16/78 K.HWPFQVINDGDKPK.V "sp|P0DMV8|HS71A_HUMAN,sp|P0DMV9|HS71B_HUMAN,tr|A0A0G2JIW1|A0A0G2JIW1_HUMAN" 3 1679.842 0.15 85798 17537 4 1679.842267 420.9678 Heat shock 70 kDa protein 1A OS=Homo sapiens OX=9606 GN=HSPA1A PE=1 SV=1 6.75 2867.4 - 3.75E+06 - - - 0.1649 - 2.752 0.502 - 159.6 1 2 0 0.0003 14 0 0 0 2.39E+08 1.60E+09 - - - 3.9638 1 221125_WJC_METTL3_EV_vs_WT_F06.17539.17539.3 3.22E-07 17/56 R.SC[160.03]TVNIMFGTPQEHR.N sp|Q9HCD5|NCOA5_HUMAN 1 1775.8083 1.63 85800 17539 3 1775.806896 592.9434 Nuclear receptor coactivator 5 OS=Homo sapiens OX=9606 GN=NCOA5 PE=1 SV=2 6.46 2867.6 - 1.02E+06 - - - -0.8041 - 3.216 0.549 - 414.7 1 2 0 -0.0014 15 0 0 0 5.01E+07 3.08E+07 - - - 7.7085 0.9999 221125_WJC_METTL3_EV_vs_WT_F06.17540.17540.3 0.00257 14/48 R.QYWDIPDGTDC[160.03]HR.K "sp|Q86Y39|NDUAB_HUMAN,tr|K7EQ77|K7EQ77_HUMAN,tr|K7EP35|K7EP35_HUMAN,tr|K7EK78|K7EK78_HUMAN,tr|K7EMT4|K7EMT4_HUMAN" 5 1661.6893 0.56 85801 17540 3 1661.691819 554.9037 NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 11 OS=Homo sapiens OX=9606 GN=NDUFA11 PE=1 SV=3 4.41 2867.7 - 858678 - - - 1.543 - 2.321 0.479 - 250.7 1 2 0 0.0026 13 0 0 0 1.22E+07 2.21E+07 - - - 6.1626 1 221125_WJC_METTL3_EV_vs_WT_F06.17541.17541.3 1.36E-13 24/96 K.AIPVSPSAVEEDEDEDGHTVVATAR.G "sp|Q07157|ZO1_HUMAN,tr|A0A087X0K9|A0A087X0K9_HUMAN,tr|H0Y3R8|H0Y3R8_HUMAN,tr|G5E9E7|G5E9E7_HUMAN,tr|A0A0G2JNH2|A0A0G2JNH2_HUMAN,tr|G3V1L9|G3V1L9_HUMAN,tr|A0A7I2V5U5|A0A7I2V5U5_HUMAN" 7 2593.2144 2.29 85802 17541 3 2593.211405 865.4121 Tight junction protein ZO-1 OS=Homo sapiens OX=9606 GN=TJP1 PE=1 SV=3 3.95 2867.8 - 811714 - - - -1.1434 - 4.197 0.726 - 677.8 1 2 0 -0.003 25 0 0 0 1.88E+07 8.19E+06 - - - 9.9333 1 221125_WJC_METTL3_EV_vs_WT_F06.17542.17542.2 7.96E-11 16/30 K.QGQISSNYDDAMQFSK[136.11].K sp|Q9Y2X9|ZN281_HUMAN 1 1825.8032 5.25 85803 17542 2 1826.801258 913.9089 Zinc finger protein 281 OS=Homo sapiens OX=9606 GN=ZNF281 PE=1 SV=1 4.21 2868 - 543059 - - - 546.6252 - 2.639 0.715 - 679.4 1 2 0 0.998 16 0 0 0 2.66E+07 5.07E+06 - - - 6.3944 0.9999 221125_WJC_METTL3_EV_vs_WT_F06.17543.17543.3 8.73E-06 21/80 K.SPSSKPSLAVAVDSAPEVAVK.E "sp|O60508|PRP17_HUMAN,tr|Q5SRN1|Q5SRN1_HUMAN" 2 2038.0946 3.81 85804 17543 3 2038.101731 680.3722 Pre-mRNA-processing factor 17 OS=Homo sapiens OX=9606 GN=CDC40 PE=1 SV=1 5.79 2868.1 - 524318 - - - 3.4812 - 4.108 0.517 - 550.7 1 2 0 0.0071 21 0 0 0 1.56E+07 4.11E+06 - - - 7.6895 1 221125_WJC_METTL3_EV_vs_WT_F06.17548.17548.3 6.48E-07 13/52 R.ENNTHPEWSFTTVR[166.11].K "sp|Q9P289|STK26_HUMAN,tr|B4E0Y9|B4E0Y9_HUMAN,tr|Q8NBY1|Q8NBY1_HUMAN" 3 1726.7939 1.14 85807 17548 3 1726.793624 576.6052 Serine\threonine-protein kinase 26 OS=Homo sapiens OX=9606 GN=STK26 PE=1 SV=2 5.4 2868.7 - 976801 - - - -0.1413 - 2.414 0.505 - 235.9 1 2 0 -0.0002 14 0 0 0 1.60E+07 1.41E+07 - - - 6.5122 1 221125_WJC_METTL3_EV_vs_WT_F06.17549.17549.3 1.80E-07 13/52 R.ENNTHPEWSFTTVR.K "sp|Q9P289|STK26_HUMAN,tr|B4E0Y9|B4E0Y9_HUMAN,tr|Q8NBY1|Q8NBY1_HUMAN" 3 1716.7856 1.12 85808 17549 3 1716.787452 573.2691 Serine\threonine-protein kinase 26 OS=Homo sapiens OX=9606 GN=STK26 PE=1 SV=2 5.4 2868.9 - 1.24E+06 - - - 1.0799 - 2.301 0.524 - 213.6 1 2 0 0.0019 14 0 0 0 1.58E+07 1.41E+07 - - - 6.5962 1 221125_WJC_METTL3_EV_vs_WT_F06.17550.17550.3 3.12E-07 20/56 R.SC[160.03]TVNIMFGTPQEHR[166.11].N sp|Q9HCD5|NCOA5_HUMAN 1 1785.8166 1.6 85809 17550 3 1785.813751 596.2795 Nuclear receptor coactivator 5 OS=Homo sapiens OX=9606 GN=NCOA5 PE=1 SV=2 6.46 2869 - 817184 - - - -1.592 - 2.748 0.509 - 365.4 1 2 0 -0.0028 15 0 0 0 5.01E+07 3.13E+07 - - - 6.8518 1 221125_WJC_METTL3_EV_vs_WT_F06.17551.17551.2 8.23E-12 22/34 K.FAASGGFLHHMAGLSSSK[136.11].L "sp|Q9BY77|PDIP3_HUMAN,tr|F6VRR5|F6VRR5_HUMAN,tr|F8WCX5|F8WCX5_HUMAN,tr|Q8WUT1|Q8WUT1_HUMAN" 4 1811.8868 1.19 85810 17551 2 1811.884496 906.9507 Polymerase delta-interacting protein 3 OS=Homo sapiens OX=9606 GN=POLDIP3 PE=1 SV=2 8.76 2869.1 - 429010 - - - -1.2926 - 4.182 0.735 - 1516.2 1 2 0 -0.0023 18 0 0 0 2.10E+07 1.76E+07 - - - 7.9866 0.9721 221125_WJC_METTL3_EV_vs_WT_F06.17555.17555.2 0.00131 16-Aug Q.VINDGDK[136.11]PK[136.11].V "sp|P0DMV8|HS71A_HUMAN,sp|P0DMV9|HS71B_HUMAN,tr|A0A0G2JIW1|A0A0G2JIW1_HUMAN" 3 1000.5524 0.15 85812 17555 2 1000.551963 501.2835 Heat shock 70 kDa protein 1A OS=Homo sapiens OX=9606 GN=HSPA1A PE=1 SV=1 5.93 2869.7 - 1.65E+06 - - - -0.4468 - 1.474 0.396 - 183.5 1 1 0 -0.0004 9 0 0 0 2.11E+07 1.38E+08 - - - 3.0882 1 221125_WJC_METTL3_EV_vs_WT_F06.17561.17561.2 1.67E-11 23/34 K.FAASGGFLHHMAGLSSSK.L "sp|Q9BY77|PDIP3_HUMAN,tr|F6VRR5|F6VRR5_HUMAN,tr|F8WCX5|F8WCX5_HUMAN,tr|Q8WUT1|Q8WUT1_HUMAN" 4 1803.8726 1.19 85818 17561 2 1803.872685 902.9436 Polymerase delta-interacting protein 3 OS=Homo sapiens OX=9606 GN=POLDIP3 PE=1 SV=2 8.76 2870.4 - 805611 - - - 0.0261 - 4.362 0.714 - 1323.7 1 2 0 0 18 0 0 0 2.10E+07 1.76E+07 - - - 7.9359 1 221125_WJC_METTL3_EV_vs_WT_F06.17566.17566.2 2.44E-10 21/28 A.SGGFLHHMAGLSSSK.L "sp|Q9BY77|PDIP3_HUMAN,tr|F6VRR5|F6VRR5_HUMAN,tr|F8WCX5|F8WCX5_HUMAN,tr|Q8WUT1|Q8WUT1_HUMAN" 4 1514.73 1.9 85823 17566 2 1514.735952 758.3723 Polymerase delta-interacting protein 3 OS=Homo sapiens OX=9606 GN=POLDIP3 PE=1 SV=2 8.51 2871.1 - 435274 - - - 3.9314 - 4.024 0.658 - 1528.4 1 1 0 0.006 15 0 0 0 7.07E+06 3.73E+06 - - - 7.3221 0.9999 221125_WJC_METTL3_EV_vs_WT_F06.17570.17570.3 1.68E-07 19/64 K.LK[136.11]K[136.11]EDIYAVEIVGGATR[166.11].L "sp|P34932|HSP74_HUMAN,tr|A0A087WTS8|A0A087WTS8_HUMAN,tr|A0A087WYC1|A0A087WYC1_HUMAN" 3 1887.0676 0.07 85825 17570 3 1887.066346 630.0298 Heat shock 70 kDa protein 4 OS=Homo sapiens OX=9606 GN=HSPA4 PE=1 SV=4 6.18 2871.5 - 1.91E+06 - - - -0.6555 - 3.302 0.548 - 392.5 1 2 1 -0.0012 17 0 0 0 1.06E+07 1.44E+08 - - - 7.6671 1 221125_WJC_METTL3_EV_vs_WT_F06.17571.17571.4 691 5/132 S.GC[160.03]GGC[160.03]GSSC[160.03]GGC[160.03]GSGC[160.03]GGC[160.03]GSGR[166.11].G sp|Q701N4|KRA52_HUMAN 1 2176.6895 0.001 85826 17571 4 2177.678312 545.1797 Keratin-associated protein 5-2 OS=Homo sapiens OX=9606 GN=KRTAP5-2 PE=1 SV=1 7.78 2871.6 - 1.58E+06 - - - 454.2664 - 0.508 0.868 - 6.1 1 1 0 0.9888 23 0 0 0 0.00E+00 1.94E+07 - - - 6.2877 0.9738 221125_WJC_METTL3_EV_vs_WT_F06.17572.17572.3 0.0391 Nov-64 K.AQLDQTGQHLFC[160.03]VC[160.03]GTR[166.11].V sp|Q12788|TBL3_HUMAN 1 1999.9232 1.06 85827 17572 3 1999.915033 667.6483 Transducin beta-like protein 3 OS=Homo sapiens OX=9606 GN=TBL3 PE=1 SV=2 6.77 2871.8 - 1.16E+06 - - - -4.0762 - 2.001 0.199 - 100.8 1 2 0 -0.0082 17 0 0 0 4.41E+07 4.18E+07 - - - 2.5088 0.9997 221125_WJC_METTL3_EV_vs_WT_F06.17575.17575.4 0.00275 Oct-78 R.GFHC[160.03]ESSAHWPIFK[136.11].W sp|P55884|EIF3B_HUMAN 1 1709.7864 0.67 85830 17575 4 1709.790475 428.4539 Eukaryotic translation initiation factor 3 subunit B OS=Homo sapiens OX=9606 GN=EIF3B PE=1 SV=3 6.91 2872.2 - 605558 - - - 2.3857 - 1.518 0.411 - 53.1 1 2 0 0.0041 14 0 0 0 7.84E+06 1.17E+07 - - - 2.9541 1 221125_WJC_METTL3_EV_vs_WT_F06.17576.17576.3 6.77E-07 18/72 K.TLQVTMPVKPTNDNDEFEK.Q sp|Q9H7E2|TDRD3_HUMAN 1 2205.0623 2.35 85831 17576 3 2205.065954 736.0281 Tudor domain-containing protein 3 OS=Homo sapiens OX=9606 GN=TDRD3 PE=1 SV=1 4.32 2872.3 - 560381 - - - 1.6349 - 3.407 0.594 - 249.8 1 2 0 0.0036 19 0 0 0 1.87E+07 7.96E+06 - - - 8.1731 0.9946 221125_WJC_METTL3_EV_vs_WT_F06.17578.17578.3 0.0261 Aug-36 R.MVNHFIAEFK[136.11].R "sp|P11142|HSP7C_HUMAN,tr|A8K7Q2|A8K7Q2_HUMAN,tr|E9PKE3|E9PKE3_HUMAN,tr|E9PN89|E9PN89_HUMAN" 4 1242.6311 0.16 85833 17578 3 1242.632023 415.2176 Heat shock cognate 71 kDa protein OS=Homo sapiens OX=9606 GN=HSPA8 PE=1 SV=1 6.5 2872.6 - 353051 - - - 0.7709 - 1.648 0.196 - 77.5 1 2 0 0.001 10 0 0 0 4.42E+06 2.83E+07 - - - 2.1839 1 221125_WJC_METTL3_EV_vs_WT_F06.17580.17580.4 2.60E-09 20/96 R.R[166.11]VPATTLYAHFEQANIK[136.11].T sp|Q7Z3B4|NUP54_HUMAN 1 1976.0599 2.56 85834 17580 4 1976.055297 495.0222 Nucleoporin p54 OS=Homo sapiens OX=9606 GN=NUP54 PE=1 SV=2 8.6 2872.8 - 887558 - - - -2.3122 - 3.525 0.6 - 345.1 1 2 0 -0.0046 17 0 0 0 1.50E+08 5.87E+07 - - - 4.8846 0.9999 221125_WJC_METTL3_EV_vs_WT_F06.17582.17582.4 2.04E-08 17/96 K.LK[136.11]K[136.11]EDIYAVEIVGGATR[166.11].L "sp|P34932|HSP74_HUMAN,tr|A0A087WTS8|A0A087WTS8_HUMAN,tr|A0A087WYC1|A0A087WYC1_HUMAN" 3 1887.0676 0.06 85835 17582 4 1887.068135 472.7742 Heat shock 70 kDa protein 4 OS=Homo sapiens OX=9606 GN=HSPA4 PE=1 SV=4 6.18 2873 - 3.51E+06 - - - 0.2925 - 3.471 0.564 - 162.3 1 2 1 0.0006 17 0 0 0 6.23E+06 1.04E+08 - - - 4.567 0.9993 221125_WJC_METTL3_EV_vs_WT_F06.17588.17588.3 0.00094 14/52 R.VKEDDLDVVLSPQR.R "sp|Q9NRA8|4ET_HUMAN,tr|B1AKL5|B1AKL5_HUMAN,tr|B1AKL4|B1AKL4_HUMAN" 3 1611.8468 1.33 85841 17588 3 1611.847313 538.2895 Eukaryotic translation initiation factor 4E transporter OS=Homo sapiens OX=9606 GN=EIF4ENIF1 PE=1 SV=2 4.23 2873.5 - 1.09E+06 - - - 0.3176 - 2.321 0.362 - 287.1 1 2 1 0.0005 14 0 0 0 2.82E+07 2.13E+07 - - - 4.8134 0.9998 221125_WJC_METTL3_EV_vs_WT_F06.17592.17592.3 3.50E-08 16/56 R.DK[136.11]LDILGAAETGSGK[136.11].T "sp|Q9GZR7|DDX24_HUMAN,tr|G3V529|G3V529_HUMAN" 2 1489.7959 1.57 85845 17592 3 1489.798395 497.6059 ATP-dependent RNA helicase DDX24 OS=Homo sapiens OX=9606 GN=DDX24 PE=1 SV=1 4.56 2874 - 783684 - - - 1.6828 - 3.438 0.42 - 391.3 1 2 1 0.0025 15 0 0 0 1.36E+07 8.62E+06 - - - 6.4442 0.9973 221125_WJC_METTL3_EV_vs_WT_F06.17594.17594.3 1.75E-06 18/64 F.AASGGFLHHMAGLSSSK[136.11].L "sp|Q9BY77|PDIP3_HUMAN,tr|F6VRR5|F6VRR5_HUMAN,tr|F8WCX5|F8WCX5_HUMAN,tr|Q8WUT1|Q8WUT1_HUMAN" 4 1664.8184 2.3 85847 17594 3 1664.820806 555.9468 Polymerase delta-interacting protein 3 OS=Homo sapiens OX=9606 GN=POLDIP3 PE=1 SV=2 8.81 2874.3 - 701109 - - - 1.4308 - 3.365 0.5 - 339.7 1 1 0 0.0024 17 0 0 0 3.23E+07 1.40E+07 - - - 7.1793 0.9797 221125_WJC_METTL3_EV_vs_WT_F06.17597.17597.4 6.60E-08 24/96 K.LDK[136.11]AQIHDLVLVGGSTR[166.11].L "sp|P0DMV8|HS71A_HUMAN,sp|P0DMV9|HS71B_HUMAN,tr|V9GZ37|V9GZ37_HUMAN,tr|A0A0G2JIW1|A0A0G2JIW1_HUMAN" 4 1839.0333 0.15 85849 17597 4 1839.032078 460.7656 Heat shock 70 kDa protein 1A OS=Homo sapiens OX=9606 GN=HSPA1A PE=1 SV=1 6.75 2874.6 - 6.41E+06 - - - -0.6737 - 3.904 0.196 - 377.7 1 2 1 -0.0012 17 0 0 0 2.10E+07 1.42E+08 - - - 1.4045 0.9998 221125_WJC_METTL3_EV_vs_WT_F06.17599.17599.3 7.19E-08 28/64 K.LDK[136.11]AQIHDLVLVGGSTR[166.11].L "sp|P0DMV8|HS71A_HUMAN,sp|P0DMV9|HS71B_HUMAN,tr|V9GZ37|V9GZ37_HUMAN,tr|A0A0G2JIW1|A0A0G2JIW1_HUMAN" 4 1839.0333 0.12 85850 17599 3 1839.034739 614.0184 Heat shock 70 kDa protein 1A OS=Homo sapiens OX=9606 GN=HSPA1A PE=1 SV=1 6.75 2874.8 - 6.49E+06 - - - 0.7732 - 4.255 0.353 - 1173.5 1 2 1 0.0014 17 0 0 0 1.81E+07 1.46E+08 - - - 6.1335 0.9999 221125_WJC_METTL3_EV_vs_WT_F06.17602.17602.3 2.07E-08 21/80 R.LC[160.03]QGEELQSDRDETGAYLIDR.D "sp|Q8N5Z5|KCD17_HUMAN,tr|H7C323|H7C323_HUMAN,tr|A0A087WX35|A0A087WX35_HUMAN,tr|H0Y731|H0Y731_HUMAN" 4 2467.1285 2.31 85853 17602 3 2467.133579 823.3835 BTB\POZ domain-containing protein KCTD17 OS=Homo sapiens OX=9606 GN=KCTD17 PE=1 SV=3 4.02 2875.1 - 2.10E+06 - - - 2.0457 - 3.266 0.579 - 541 1 2 1 0.005 21 0 0 0 3.40E+07 1.47E+07 - - - 7.8314 0.9036 221125_WJC_METTL3_EV_vs_WT_F06.17615.17615.3 1.27E-05 16/64 F.AASGGFLHHMAGLSSSK.L "sp|Q9BY77|PDIP3_HUMAN,tr|F6VRR5|F6VRR5_HUMAN,tr|F8WCX5|F8WCX5_HUMAN,tr|Q8WUT1|Q8WUT1_HUMAN" 4 1656.8042 1.89 85864 17615 3 1657.808171 553.2754 Polymerase delta-interacting protein 3 OS=Homo sapiens OX=9606 GN=POLDIP3 PE=1 SV=2 8.81 2876.5 - 594266 - - - 605.9539 - 2.907 0.467 - 216.7 1 1 0 1.0039 17 0 0 0 2.15E+07 1.14E+07 - - - 6.1644 0.7686 221125_WJC_METTL3_EV_vs_WT_F06.17619.17619.3 3.04 May-36 R.MVNHFIAEFK.R "sp|P11142|HSP7C_HUMAN,tr|A8K7Q2|A8K7Q2_HUMAN,tr|E9PKE3|E9PKE3_HUMAN,tr|E9PN89|E9PN89_HUMAN" 4 1234.6169 0.15 85868 17619 3 1234.618197 412.5462 Heat shock cognate 71 kDa protein OS=Homo sapiens OX=9606 GN=HSPA8 PE=1 SV=1 6.5 2877.1 - 359294 - - - 1.0789 - 1.199 0.102 - 33 3 2 0 0.0013 10 0 0 0 4.24E+06 2.81E+07 - - - -0.014 1 221125_WJC_METTL3_EV_vs_WT_F06.17622.17622.3 1.43E-08 18/52 K.GSYNDFSFVTHTNR[166.11].E "sp|Q9UG56|PISD_HUMAN,tr|H0Y7P7|H0Y7P7_HUMAN" 2 1653.7411 0.68 85869 17622 3 1653.742775 552.2543 "Phosphatidylserine decarboxylase proenzyme, mitochondrial OS=Homo sapiens OX=9606 GN=PISD PE=1 SV=4" 6.74 2877.5 - 1.07E+06 - - - 1.0104 - 2.93 0.559 - 309.3 1 2 0 0.0017 14 0 0 0 9.76E+06 1.44E+07 - - - 7.6287 0.9999 221125_WJC_METTL3_EV_vs_WT_F06.17624.17624.3 2.08E-07 19/52 R.VK[136.11]EDDLDVVLSPQR[166.11].R "sp|Q9NRA8|4ET_HUMAN,tr|B1AKL5|B1AKL5_HUMAN,tr|B1AKL4|B1AKL4_HUMAN" 3 1629.8693 1.33 85871 17624 3 1629.869679 544.297 Eukaryotic translation initiation factor 4E transporter OS=Homo sapiens OX=9606 GN=EIF4ENIF1 PE=1 SV=2 4.23 2877.7 - 822795 - - - 0.2503 - 3.154 0.523 - 588.6 1 2 1 0.0004 14 0 0 0 2.82E+07 2.13E+07 - - - 7.4235 1 221125_WJC_METTL3_EV_vs_WT_F06.17632.17632.3 3.23E-11 21/68 R.QAHLC[160.03]VLASNC[160.03]DEPMYVK.L sp|P25398|RS12_HUMAN 1 2133.9646 2.03 85877 17632 3 2133.964119 712.3288 40S ribosomal protein S12 OS=Homo sapiens OX=9606 GN=RPS12 PE=1 SV=3 5.32 2878.7 - 1.85E+06 - - - -0.2099 - 4.237 0.659 - 699 1 2 0 -0.0004 18 0 0 0 1.33E+08 6.55E+07 - - - 9.4824 0.9996 221125_WJC_METTL3_EV_vs_WT_F06.17633.17633.4 2.08E-05 15/96 K.LDKAQIHDLVLVGGSTR.L "sp|P0DMV8|HS71A_HUMAN,sp|P0DMV9|HS71B_HUMAN,tr|V9GZ37|V9GZ37_HUMAN,tr|A0A0G2JIW1|A0A0G2JIW1_HUMAN" 4 1821.0108 0.14 85878 17633 4 1821.01372 456.26 Heat shock 70 kDa protein 1A OS=Homo sapiens OX=9606 GN=HSPA1A PE=1 SV=1 6.75 2878.8 - 1.17E+06 - - - 1.5777 - 2.956 0.435 - 151.4 1 2 1 0.0029 17 0 0 0 2.28E+07 1.60E+08 - - - 3.3877 0.9999 221125_WJC_METTL3_EV_vs_WT_F06.17635.17635.3 1.81E-07 17/76 K.YEEAEK[136.11]DC[160.03]TQAILLDGSYSK[136.11].A sp|Q9H6T3|RPAP3_HUMAN 1 2335.0861 0.98 85880 17635 3 2335.089884 779.3693 RNA polymerase II-associated protein 3 OS=Homo sapiens OX=9606 GN=RPAP3 PE=1 SV=2 4.18 2879.1 - 507709 - - - 1.6385 - 3.016 0.612 - 371 1 2 1 0.0038 20 0 0 0 1.10E+07 1.13E+07 - - - 8.0403 0.9937 221125_WJC_METTL3_EV_vs_WT_F06.17636.17636.3 0.194 Sep-48 K.ASLASLPPLHVAK.L "sp|Q14203|DCTN1_HUMAN,tr|A0A804CDA6|A0A804CDA6_HUMAN,tr|E7EX90|E7EX90_HUMAN,tr|A0A7P0Z4C3|A0A7P0Z4C3_HUMAN,tr|E7EWF7|E7EWF7_HUMAN" 5 1302.766 2.21 85881 17636 3 1302.765751 435.2626 Dynactin subunit 1 OS=Homo sapiens OX=9606 GN=DCTN1 PE=1 SV=3 8.8 2879.2 - 207445 - - - -0.1696 - 1.566 0.209 - 121.6 1 2 0 -0.0002 13 0 0 0 5.35E+06 2.42E+06 - - - 2.0862 1 221125_WJC_METTL3_EV_vs_WT_F06.17638.17638.3 3.15E-09 29/64 R.RVPATTLYAHFEQANIK.T sp|Q7Z3B4|NUP54_HUMAN 1 1958.0374 2.08 85882 17638 3 1958.039965 653.6864 Nucleoporin p54 OS=Homo sapiens OX=9606 GN=NUP54 PE=1 SV=2 8.6 2879.4 - 2.54E+06 - - - 1.312 - 5.687 0.688 - 1924.3 1 2 0 0.0026 17 0 0 0 5.22E+07 2.51E+07 - - - 10.601 1 221125_WJC_METTL3_EV_vs_WT_F06.17641.17641.3 1.25E-09 19/76 K.IDSIADHVNSAAVNVEEGTK.N sp|P56962|STX17_HUMAN 1 2068.0073 1.26 85884 17641 3 2068.011305 690.343 Syntaxin-17 OS=Homo sapiens OX=9606 GN=STX17 PE=1 SV=2 4.31 2879.6 - 3.96E+06 - - - 1.9478 - 3.597 0.634 - 319.6 1 2 0 0.004 20 0 0 0 1.03E+08 8.15E+07 - - - 8.7129 1 221125_WJC_METTL3_EV_vs_WT_F06.17648.17648.3 2.32E-11 23/64 R.R[166.11]VPATTLYAHFEQANIK[136.11].T sp|Q7Z3B4|NUP54_HUMAN 1 1976.0599 2.08 85889 17648 3 1976.060678 659.6939 Nucleoporin p54 OS=Homo sapiens OX=9606 GN=NUP54 PE=1 SV=2 8.6 2880.6 - 1.11E+06 - - - 0.4109 - 4.137 0.632 - 658 1 2 0 0.0008 17 0 0 0 5.21E+07 2.51E+07 - - - 9.1732 1 221125_WJC_METTL3_EV_vs_WT_F06.17653.17653.3 8.11E-08 17/76 K.YEEAEKDC[160.03]TQAILLDGSYSK.A sp|Q9H6T3|RPAP3_HUMAN 1 2319.0577 0.98 85892 17653 3 2319.056783 774.0265 RNA polymerase II-associated protein 3 OS=Homo sapiens OX=9606 GN=RPAP3 PE=1 SV=2 4.18 2881.2 - 502155 - - - -0.3773 - 3.016 0.659 - 294.4 1 2 1 -0.0009 20 0 0 0 1.10E+07 1.13E+07 - - - 8.5651 0.9999 221125_WJC_METTL3_EV_vs_WT_F06.17654.17654.3 0.00058 Sep-56 R.QEQGAENEELHQLWR[166.11].K "sp|Q6PGP7|TTC37_HUMAN,tr|H0Y964|H0Y964_HUMAN,tr|D6RCE2|D6RCE2_HUMAN" 3 1875.8739 0.62 85893 17654 3 1875.871889 626.2986 Tetratricopeptide repeat protein 37 OS=Homo sapiens OX=9606 GN=TTC37 PE=1 SV=1 4.48 2881.4 - 312987 - - - -1.0768 - 2.021 0.437 - 123.8 1 2 0 -0.002 15 0 0 0 1.30E+06 2.11E+06 - - - 5.2475 0.9998 221125_WJC_METTL3_EV_vs_WT_F06.17657.17657.3 0.000167 Sep-48 R.EHQISPGDFPSLR[166.11].K "sp|Q9H4M9|EHD1_HUMAN,tr|C9JC03|C9JC03_HUMAN,tr|C9J2Z4|C9J2Z4_HUMAN,tr|A0A024R571|A0A024R571_HUMAN" 4 1491.7346 1.35 85896 17657 3 1491.739553 498.2521 EH domain-containing protein 1 OS=Homo sapiens OX=9606 GN=EHD1 PE=1 SV=2 5.32 2881.8 - 221162 - - - 3.3458 - 2.305 0.492 - 91.3 1 2 0 0.005 13 0 0 0 5.41E+06 4.00E+06 - - - 6.2881 1 221125_WJC_METTL3_EV_vs_WT_F06.17660.17660.2 1.61E-09 18/40 K.FGVSSSSSGPSQTLTSTGNFK.F sp|P49790|NU153_HUMAN 1 2074.9807 3.08 85897 17660 2 2074.987391 1038.4976 Nuclear pore complex protein Nup153 OS=Homo sapiens OX=9606 GN=NUP153 PE=1 SV=2 8.75 2882.2 - 384800 - - - 3.2111 - 3.411 0.613 - 443.4 1 2 0 0.0067 21 0 0 0 4.20E+07 1.36E+07 - - - 6.5832 0.9999 221125_WJC_METTL3_EV_vs_WT_F06.17666.17666.3 2.38E-05 Dec-80 R.QINTLSHGEVVC[160.03]AVTISNPTR[166.11].H "sp|Q04726|TLE3_HUMAN,tr|A0A0D9SES8|A0A0D9SES8_HUMAN,tr|H0YL70|H0YL70_HUMAN,tr|H0YKN8|H0YKN8_HUMAN,tr|H0YKT5|H0YKT5_HUMAN,tr|H0YLI3|H0YLI3_HUMAN,tr|H0YNI7|H0YNI7_HUMAN,tr|H0YNT2|H0YNT2_HUMAN" 8 2305.1724 1.99 85903 17666 3 2305.175628 769.3981 Transducin-like enhancer protein 3 OS=Homo sapiens OX=9606 GN=TLE3 PE=1 SV=2 6.74 2882.9 - 190929 - - - 1.4008 - 2.498 0.487 - 140.6 1 2 0 0.0032 21 0 0 0 2.09E+07 1.05E+07 - - - 6.1635 1 221125_WJC_METTL3_EV_vs_WT_F06.17669.17669.3 4.93E-18 22/96 K.LVQDVANNTNEEAGDGTTTATVLAR.S "sp|P10809|CH60_HUMAN,tr|C9JL25|C9JL25_HUMAN,tr|A0A7I2V2X6|A0A7I2V2X6_HUMAN,tr|A0A7I2YQK6|A0A7I2YQK6_HUMAN,tr|A0A7I2V599|A0A7I2V599_HUMAN,tr|E7EXB4|E7EXB4_HUMAN,tr|A0A7I2YQ71|A0A7I2YQ71_HUMAN,tr|E7ESH4|E7ESH4_HUMAN,tr|A0A7I2V5M1|A0A7I2V5M1_HUMAN,tr|A0A7I2V5K3|A0A7I2V5K3_HUMAN,tr|A0A7I2V369|A0A7I2V369_HUMAN" 11 2559.2413 1.26 85905 17669 3 2559.243549 854.0877 "60 kDa heat shock protein, mitochondrial OS=Homo sapiens OX=9606 GN=HSPD1 PE=1 SV=2" 3.92 2883.2 - 2.11E+06 - - - 0.8971 - 4.036 0.744 - 639.4 1 2 0 0.0023 25 0 0 0 5.22E+07 4.13E+07 - - - 10.0442 1 221125_WJC_METTL3_EV_vs_WT_F06.17670.17670.2 2.56E-12 17/38 R.FSSC[160.03]GGGGGSFGAGGGFGSR.S sp|P04264|K2C1_HUMAN 1 1764.7274 86.15 85906 17670 2 1764.730465 883.371 "Keratin, type II cytoskeletal 1 OS=Homo sapiens OX=9606 GN=KRT1 PE=1 SV=6" 8.25 2883.4 - 836042 - - - 1.7192 - 4.016 0.771 - 885.3 1 2 0 0.003 20 0 0 0 3.13E+07 3.63E+05 - - - 8.1527 1 221125_WJC_METTL3_EV_vs_WT_F06.17671.17671.3 3.85E-06 15/48 R.K[136.11]EFSPFGTITSAK[136.11].V "sp|P11940|PABP1_HUMAN,tr|A0A7I2YQE4|A0A7I2YQE4_HUMAN,tr|A0A7I2V649|A0A7I2V649_HUMAN,tr|H0YB86|H0YB86_HUMAN,tr|H0YAR2|H0YAR2_HUMAN,tr|E7ERJ7|E7ERJ7_HUMAN,tr|A0A7I2YQ88|A0A7I2YQ88_HUMAN,tr|A0A087WTT1|A0A087WTT1_HUMAN,tr|H0YAP2|H0YAP2_HUMAN,tr|A0A7I2V4N4|A0A7I2V4N4_HUMAN,tr|E7EQV3|E7EQV3_HUMAN" 11 1427.7631 1.55 85907 17671 3 1427.766392 476.9283 Polyadenylate-binding protein 1 OS=Homo sapiens OX=9606 GN=PABPC1 PE=1 SV=2 8.59 2883.5 - 1.09E+06 - - - 2.284 - 2.548 0.544 - 310.6 1 2 0 0.0033 13 0 0 0 2.42E+07 1.56E+07 - - - 7.1401 1 221125_WJC_METTL3_EV_vs_WT_F06.17673.17673.3 7.73E-09 17/48 R.DLNYC[160.03]FSGMSDHR[166.11].Y "sp|P55795|HNRH2_HUMAN,sp|P31943|HNRH1_HUMAN,tr|H0YBD7|H0YBD7_HUMAN,tr|H0YB39|H0YB39_HUMAN,tr|H0YBG7|H0YBG7_HUMAN,tr|E9PCY7|E9PCY7_HUMAN,tr|G8JLB6|G8JLB6_HUMAN" 7 1610.6481 1.1 85909 17673 3 1610.652319 537.89 Heterogeneous nuclear ribonucleoprotein H2 OS=Homo sapiens OX=9606 GN=HNRNPH2 PE=1 SV=1 5.21 2883.7 - 872896 - - - 2.5996 - 2.264 0.668 - 344.4 1 2 0 0.0042 13 0 0 0 1.15E+08 1.05E+08 - - - 8.2019 1 221125_WJC_METTL3_EV_vs_WT_F06.17677.17677.3 1.22E-06 16/80 R.QINTLSHGEVVC[160.03]AVTISNPTR.H "sp|Q04726|TLE3_HUMAN,tr|A0A0D9SES8|A0A0D9SES8_HUMAN,tr|H0YL70|H0YL70_HUMAN,tr|H0YKN8|H0YKN8_HUMAN,tr|H0YKT5|H0YKT5_HUMAN,tr|H0YLI3|H0YLI3_HUMAN,tr|H0YNI7|H0YNI7_HUMAN,tr|H0YNT2|H0YNT2_HUMAN" 8 2295.1641 1.99 85911 17677 3 2295.165993 766.062 Transducin-like enhancer protein 3 OS=Homo sapiens OX=9606 GN=TLE3 PE=1 SV=2 6.74 2884.2 - 753881 - - - 0.8121 - 3.171 0.552 - 259.1 1 2 0 0.0019 21 0 0 0 2.09E+07 1.05E+07 - - - 7.4605 0.9948 221125_WJC_METTL3_EV_vs_WT_F06.17679.17679.3 0.000559 Sep-40 R.KEDWNEIDPIK.K sp|Q10471|GALT2_HUMAN 1 1385.6827 1.54 85913 17679 3 1385.692388 462.9015 Polypeptide N-acetylgalactosaminyltransferase 2 OS=Homo sapiens OX=9606 GN=GALNT2 PE=1 SV=1 4.32 2884.5 - 360293 - - - 6.9944 - 1.948 0.437 - 83.2 1 2 0 0.0097 11 0 0 0 9.29E+06 6.01E+06 - - - 5.3037 0.9997 221125_WJC_METTL3_EV_vs_WT_F06.17680.17680.3 2.66E-07 Dec-76 R.FSSC[160.03]GGGGGSFGAGGGFGSR.S sp|P04264|K2C1_HUMAN 1 1764.7274 1.54 85914 17680 3 1764.736078 589.2498 "Keratin, type II cytoskeletal 1 OS=Homo sapiens OX=9606 GN=KRT1 PE=1 SV=6" 8.25 2884.6 - 341377 - - - 4.8999 - 2.507 0.561 - 121.2 1 2 0 0.0086 20 0 0 0 9.61E+06 6.24E+06 - - - 7.0219 0.9984 221125_WJC_METTL3_EV_vs_WT_F06.17681.17681.3 4.01E-05 Dec-60 K.DVYVDSKDPVSSLQVK.A sp|Q9P032|NDUF4_HUMAN 1 1777.9098 0.78 85915 17681 3 1777.914593 593.6439 NADH dehydrogenase [ubiquinone] 1 alpha subcomplex assembly factor 4 OS=Homo sapiens OX=9606 GN=NDUFAF4 PE=1 SV=1 4.43 2884.7 - 340063 - - - 2.6987 - 1.89 0.438 - 105.1 1 2 1 0.0048 16 0 0 0 6.98E+06 9.00E+06 - - - 5.0553 0.9999 221125_WJC_METTL3_EV_vs_WT_F06.17685.17685.3 7.84E-06 Dec-48 R.DLNYC[160.03]FSGMSDHR.Y "sp|P55795|HNRH2_HUMAN,sp|P31943|HNRH1_HUMAN,tr|H0YBD7|H0YBD7_HUMAN,tr|H0YB39|H0YB39_HUMAN,tr|H0YBG7|H0YBG7_HUMAN,tr|E9PCY7|E9PCY7_HUMAN,tr|G8JLB6|G8JLB6_HUMAN" 7 1600.6399 1.09 85917 17685 3 1600.644922 534.5539 Heterogeneous nuclear ribonucleoprotein H2 OS=Homo sapiens OX=9606 GN=HNRNPH2 PE=1 SV=1 5.21 2885.3 - 2.59E+06 - - - 3.1612 - 2.374 0.626 - 160.8 1 2 0 0.0051 13 0 0 0 1.14E+08 1.05E+08 - - - 7.862 0.9999 221125_WJC_METTL3_EV_vs_WT_F06.17686.17686.3 0.000133 14/48 R.KEFSPFGTITSAK.V "sp|P11940|PABP1_HUMAN,tr|A0A7I2YQE4|A0A7I2YQE4_HUMAN,tr|A0A7I2V649|A0A7I2V649_HUMAN,tr|H0YB86|H0YB86_HUMAN,tr|H0YAR2|H0YAR2_HUMAN,tr|E7ERJ7|E7ERJ7_HUMAN,tr|A0A7I2YQ88|A0A7I2YQ88_HUMAN,tr|A0A087WTT1|A0A087WTT1_HUMAN,tr|H0YAP2|H0YAP2_HUMAN,tr|A0A7I2V4N4|A0A7I2V4N4_HUMAN,tr|E7EQV3|E7EQV3_HUMAN" 11 1411.7347 1.54 85918 17686 3 1411.738952 471.5855 Polyadenylate-binding protein 1 OS=Homo sapiens OX=9606 GN=PABPC1 PE=1 SV=2 8.59 2885.4 - 1.28E+06 - - - 2.9899 - 3.006 0.491 - 279.9 1 2 0 0.0042 13 0 0 0 2.42E+07 1.58E+07 - - - 6.9971 0.9999 221125_WJC_METTL3_EV_vs_WT_F06.17694.17694.3 6.11E-07 14/52 K.SFFDNISC[160.03]DDNR[166.11]ER[166.11].R "sp|Q8ND56|LS14A_HUMAN,tr|A0A096LP11|A0A096LP11_HUMAN,tr|A0A140TA76|A0A140TA76_HUMAN,tr|A0A0G2JQ95|A0A0G2JQ95_HUMAN" 4 1793.7542 0.51 85924 17694 3 1793.756083 598.9253 Protein LSM14 homolog A OS=Homo sapiens OX=9606 GN=LSM14A PE=1 SV=3 4.23 2886.3 - 1.35E+06 - - - 1.0492 - 2.249 0.603 - 196.9 1 2 1 0.0019 14 0 0 0 3.37E+06 6.64E+06 - - - 7.4162 1 221125_WJC_METTL3_EV_vs_WT_F06.17695.17695.4 2.92E-06 15/108 R.GLLQDDAHPTLVTYADHSK[136.11].L "sp|Q86U44|MTA70_HUMAN,tr|F5H6D8|F5H6D8_HUMAN,tr|H0YFV6|H0YFV6_HUMAN,tr|B4DTN4|B4DTN4_HUMAN" 4 2088.0367 0.04 85925 17695 4 2088.042741 523.0165 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 5.13 2886.3 - 9.94E+06 - - - 2.8773 - 2.902 0.585 - 185.5 1 2 0 0.006 19 0 0 0 1.03E+07 2.46E+08 - - - 4.6766 0.9994 221125_WJC_METTL3_EV_vs_WT_F06.17696.17696.3 5.06E-06 13/52 K.SFFDNISC[160.03]DDNRER.R "sp|Q8ND56|LS14A_HUMAN,tr|A0A096LP11|A0A096LP11_HUMAN,tr|A0A140TA76|A0A140TA76_HUMAN,tr|A0A0G2JQ95|A0A0G2JQ95_HUMAN" 4 1773.7377 0.49 85926 17696 3 1773.743767 592.2532 Protein LSM14 homolog A OS=Homo sapiens OX=9606 GN=LSM14A PE=1 SV=3 4.23 2886.5 - 984217 - - - 3.4424 - 2.103 0.563 - 163.1 1 2 1 0.0061 14 0 0 0 3.19E+06 6.49E+06 - - - 6.7907 1 221125_WJC_METTL3_EV_vs_WT_F06.17702.17702.3 1.37E-13 24/96 K.LVQDVANNTNEEAGDGTTTATVLAR[166.11].S "sp|P10809|CH60_HUMAN,tr|C9JL25|C9JL25_HUMAN,tr|A0A7I2V2X6|A0A7I2V2X6_HUMAN,tr|A0A7I2YQK6|A0A7I2YQK6_HUMAN,tr|A0A7I2V599|A0A7I2V599_HUMAN,tr|E7EXB4|E7EXB4_HUMAN,tr|A0A7I2YQ71|A0A7I2YQ71_HUMAN,tr|E7ESH4|E7ESH4_HUMAN,tr|A0A7I2V5M1|A0A7I2V5M1_HUMAN,tr|A0A7I2V5K3|A0A7I2V5K3_HUMAN,tr|A0A7I2V369|A0A7I2V369_HUMAN" 11 2569.2495 1.26 85931 17702 3 2569.253494 857.4238 "60 kDa heat shock protein, mitochondrial OS=Homo sapiens OX=9606 GN=HSPD1 PE=1 SV=2" 3.92 2887.2 - 1.64E+06 - - - 1.5456 - 4.055 0.706 - 779.5 1 2 0 0.004 25 0 0 0 5.22E+07 4.13E+07 - - - 9.6309 1 221125_WJC_METTL3_EV_vs_WT_F06.17703.17703.4 5.51E-09 16/78 K.HWPFQVINDGDK[136.11]PK[136.11].V "sp|P0DMV8|HS71A_HUMAN,sp|P0DMV9|HS71B_HUMAN,tr|A0A0G2JIW1|A0A0G2JIW1_HUMAN" 3 1695.8704 0.15 85932 17703 4 1695.87361 424.9749 Heat shock 70 kDa protein 1A OS=Homo sapiens OX=9606 GN=HSPA1A PE=1 SV=1 6.75 2887.3 - 648034 - - - 1.8987 - 2.691 0.562 - 179 1 2 0 0.0032 14 0 0 0 2.39E+08 1.60E+09 - - - 4.477 0.9996 221125_WJC_METTL3_EV_vs_WT_F06.17705.17705.4 0.000115 23/90 K.QIYYSDKYFDEHYEYR.H sp|P33552|CKS2_HUMAN 1 2217.9644 1.07 85934 17705 4 2217.972624 555.4984 Cyclin-dependent kinases regulatory subunit 2 OS=Homo sapiens OX=9606 GN=CKS2 PE=1 SV=1 4.75 2887.5 - 617056 - - - 3.7304 - 3.951 0.547 - 626.2 1 2 1 0.0083 16 0 0 0 5.55E+06 5.19E+06 - - - 4.4688 0.9999 221125_WJC_METTL3_EV_vs_WT_F06.17708.17708.3 5.29E-05 15/88 K.LEEDISSSMTNSTAASR[166.11]PPVTLR[166.11].L "sp|Q15366|PCBP2_HUMAN,tr|F8W1G6|F8W1G6_HUMAN,tr|F8VZX2|F8VZX2_HUMAN,tr|F8W0G4|F8W0G4_HUMAN,tr|F8VXH9|F8VXH9_HUMAN,tr|H3BRU6|H3BRU6_HUMAN,tr|H3BND9|H3BND9_HUMAN" 7 2481.2284 1.29 85937 17708 3 2481.233743 828.0834 Poly(rC)-binding protein 2 OS=Homo sapiens OX=9606 GN=PCBP2 PE=1 SV=1 4.68 2887.9 - 229233 - - - 2.1505 - 2.607 0.485 - 215.9 1 2 0 0.0053 23 0 0 0 3.21E+07 2.49E+07 - - - 6.1937 0.9999 221125_WJC_METTL3_EV_vs_WT_F06.17711.17711.3 3.26E-07 19/52 K.HWPFQVINDGDK[136.11]PK[136.11].V "sp|P0DMV8|HS71A_HUMAN,sp|P0DMV9|HS71B_HUMAN,tr|A0A0G2JIW1|A0A0G2JIW1_HUMAN" 3 1695.8704 -1 85939 17711 3 1695.877787 566.2974 Heat shock 70 kDa protein 1A OS=Homo sapiens OX=9606 GN=HSPA1A PE=1 SV=1 6.75 2888.3 - 2.60E+06 - - - 4.3618 - 3.221 0.573 - 674 1 2 0 0.0074 14 0 0 0 0.00E+00 0.00E+00 - - - 8.0348 0.9985 221125_WJC_METTL3_EV_vs_WT_F06.17715.17715.3 2.60E-08 21/72 A.K[136.11]QITSYGETC[160.03]PGLEQYAIK[136.11].K sp|P50990|TCPQ_HUMAN 1 2201.1009 0.43 85942 17715 3 2201.102285 734.7076 T-complex protein 1 subunit theta OS=Homo sapiens OX=9606 GN=CCT8 PE=1 SV=4 6.13 2888.7 - 1.80E+06 - - - 0.6201 - 3.523 0.531 - 500.4 1 1 0 0.0014 19 0 0 0 4.98E+07 1.17E+08 - - - 7.5536 0.9988 221125_WJC_METTL3_EV_vs_WT_F06.17720.17720.2 2.68E-05 13/26 K.SFFDNISC[160.03]DDNR[166.11]ER[166.11].R "sp|Q8ND56|LS14A_HUMAN,tr|A0A096LP11|A0A096LP11_HUMAN,tr|A0A140TA76|A0A140TA76_HUMAN,tr|A0A0G2JQ95|A0A0G2JQ95_HUMAN" 4 1793.7542 1.03 85947 17720 2 1793.754013 897.8844 Protein LSM14 homolog A OS=Homo sapiens OX=9606 GN=LSM14A PE=1 SV=3 4.23 2889.3 - 453551 - - - -0.1048 - 2.113 0.557 - 238.5 1 2 1 -0.0002 14 0 0 0 8.17E+08 7.93E+08 - - - 5.0323 0.9976 221125_WJC_METTL3_EV_vs_WT_F06.17727.17727.2 0.0001 13/26 K.SFFDNISC[160.03]DDNRER.R "sp|Q8ND56|LS14A_HUMAN,tr|A0A096LP11|A0A096LP11_HUMAN,tr|A0A140TA76|A0A140TA76_HUMAN,tr|A0A0G2JQ95|A0A0G2JQ95_HUMAN" 4 1773.7377 1.03 85952 17727 2 1773.739756 887.8761 Protein LSM14 homolog A OS=Homo sapiens OX=9606 GN=LSM14A PE=1 SV=3 4.23 2890.2 - 1.09E+06 - - - 1.1811 - 1.936 0.513 - 222 1 2 1 0.0021 14 0 0 0 8.17E+08 7.94E+08 - - - 4.4872 0.9967 221125_WJC_METTL3_EV_vs_WT_F06.17729.17729.3 3.27E-08 16/72 A.KQITSYGETC[160.03]PGLEQYAIK.K sp|P50990|TCPQ_HUMAN 1 2185.0725 0.42 85954 17729 3 2185.076454 729.3648 T-complex protein 1 subunit theta OS=Homo sapiens OX=9606 GN=CCT8 PE=1 SV=4 6.13 2890.4 - 1.01E+06 - - - 1.8004 - 3.225 0.516 - 275.7 1 1 0 0.0039 19 0 0 0 4.89E+07 1.17E+08 - - - 7.1686 0.9995 221125_WJC_METTL3_EV_vs_WT_F06.17731.17731.3 0.00911 14/80 K.QLQEETPPGGPLTEALPPARK.E "sp|Q9Y6M9|NDUB9_HUMAN,tr|A0A7I2V620|A0A7I2V620_HUMAN,tr|E9PH64|E9PH64_HUMAN" 3 2228.1801 5.04 85956 17731 3 2228.182695 743.734 NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 9 OS=Homo sapiens OX=9606 GN=NDUFB9 PE=1 SV=3 4.79 2890.6 - 567687 - - - 1.166 - 2.164 0.325 - 59.6 1 2 0 0.0026 21 0 0 0 3.81E+07 7.56E+06 - - - 4.0134 0.9993 221125_WJC_METTL3_EV_vs_WT_F06.17732.17732.3 7.50E-05 Oct-52 K.SFFDNISC[160.03]DDNRER[166.11].R "sp|Q8ND56|LS14A_HUMAN,tr|A0A096LP11|A0A096LP11_HUMAN,tr|A0A140TA76|A0A140TA76_HUMAN,tr|A0A0G2JQ95|A0A0G2JQ95_HUMAN" 4 1783.7459 - 85957 17732 3 1783.74722 595.5893 Protein LSM14 homolog A OS=Homo sapiens OX=9606 GN=LSM14A PE=1 SV=3 4.23 2890.8 - 505370 - - - 0.7226 - 1.778 0.422 - 79.1 1 2 1 0.0013 14 0 0 0 - - - - - 4.7739 0.9996 221125_WJC_METTL3_EV_vs_WT_F06.17738.17738.4 2.10E-05 19/102 K.ELTDEEAERLQLEIDQKK.D "sp|Q9Y266|NUDC_HUMAN,tr|A0A0A0MSS4|A0A0A0MSS4_HUMAN,tr|A0A0A0MSU9|A0A0A0MSU9_HUMAN" 3 2186.1067 2.24 85961 17738 4 2186.108607 547.5339 Nuclear migration protein nudC OS=Homo sapiens OX=9606 GN=NUDC PE=1 SV=1 4.25 2891.5 - 1.30E+06 - - - 0.892 - 3.083 0.418 - 283.5 1 2 1 0.0019 18 0 0 0 2.38E+07 1.07E+07 - - - 3.2494 1 221125_WJC_METTL3_EV_vs_WT_F06.17740.17740.3 2.27E-08 19/88 K.LEEDISSSMTNSTAASRPPVTLR.L "sp|Q15366|PCBP2_HUMAN,tr|F8W1G6|F8W1G6_HUMAN,tr|F8VZX2|F8VZX2_HUMAN,tr|F8W0G4|F8W0G4_HUMAN,tr|F8VXH9|F8VXH9_HUMAN,tr|H3BRU6|H3BRU6_HUMAN,tr|H3BND9|H3BND9_HUMAN" 7 2461.2119 1.29 85963 17740 3 2461.218951 821.4112 Poly(rC)-binding protein 2 OS=Homo sapiens OX=9606 GN=PCBP2 PE=1 SV=1 4.68 2891.8 - 910584 - - - 2.8783 - 3.506 0.574 - 302.5 1 2 0 0.0071 23 0 0 0 3.20E+07 2.49E+07 - - - 7.8805 0.9999 221125_WJC_METTL3_EV_vs_WT_F06.17741.17741.4 0.00647 22/96 R.QLQQEQAYLLSLQHDHR[166.11].R "sp|O95819|M4K4_HUMAN,tr|H7C3Z6|H7C3Z6_HUMAN,tr|A0A0D9SEY1|A0A0D9SEY1_HUMAN,tr|C9J840|C9J840_HUMAN,tr|E7EX83|E7EX83_HUMAN,tr|A0A0D9SG62|A0A0D9SG62_HUMAN,tr|H7C0P6|H7C0P6_HUMAN" 7 2116.0689 1.28 85964 17741 4 2116.066089 530.0245 Mitogen-activated protein kinase kinase kinase kinase 4 OS=Homo sapiens OX=9606 GN=MAP4K4 PE=1 SV=2 5.99 2891.9 - 804744 - - - -1.3379 - 4.043 0.382 - 434.8 1 2 0 -0.0028 17 0 0 0 1.10E+07 8.63E+06 - - - 3.0352 0.9999 221125_WJC_METTL3_EV_vs_WT_F06.17742.17742.3 2.23E-10 18/60 K.LDVFQSYQSATHEQTK.A "sp|Q13439|GOGA4_HUMAN,tr|H0Y6I0|H0Y6I0_HUMAN,tr|C9JHJ5|C9JHJ5_HUMAN" 3 1880.8905 11.2 85965 17742 3 1880.898017 627.9708 Golgin subfamily A member 4 OS=Homo sapiens OX=9606 GN=GOLGA4 PE=1 SV=1 5.32 2892 - 735463 - - - 4.0194 - 3.445 0.594 - 499.3 1 2 0 0.0076 16 0 0 0 2.16E+08 1.93E+07 - - - 8.3342 1 221125_WJC_METTL3_EV_vs_WT_F06.17743.17743.2 3.49E-10 15/38 R.ESTGAQVQVAGDMLPNSTER.A "sp|P57721|PCBP3_HUMAN,sp|Q15366|PCBP2_HUMAN,sp|Q15365|PCBP1_HUMAN,tr|E9PFP8|E9PFP8_HUMAN,tr|J3QT27|J3QT27_HUMAN,tr|F8VZX2|F8VZX2_HUMAN,tr|F8W0G4|F8W0G4_HUMAN,tr|F8VXH9|F8VXH9_HUMAN,tr|H3BRU6|H3BRU6_HUMAN" 9 2088.9746 1.31 85966 17743 2 2088.9802 1045.4946 Poly(rC)-binding protein 3 OS=Homo sapiens OX=9606 GN=PCBP3 PE=1 SV=2 4.14 2892.2 - 548026 - - - 2.6822 - 2.866 0.641 - 505.7 1 2 0 0.0056 20 0 0 0 1.89E+08 1.44E+08 - - - 6.3623 1 221125_WJC_METTL3_EV_vs_WT_F06.17746.17746.2 7.33E-12 18/32 K.NVSGISFTENMGSSQQK[136.11].N sp|P49792|RBP2_HUMAN 1 1820.8454 0.46 85969 17746 2 1820.84129 911.43 E3 SUMO-protein ligase RanBP2 OS=Homo sapiens OX=9606 GN=RANBP2 PE=1 SV=2 6 2892.6 - 382550 - - - -2.272 - 3.369 0.721 - 812.2 1 2 0 -0.0041 17 0 0 0 3.44E+06 7.53E+06 - - - 7.3512 0.9992 221125_WJC_METTL3_EV_vs_WT_F06.17747.17747.4 4.18E-05 15/102 K.ELTDEEAER[166.11]LQLEIDQK[136.11]K[136.11].D "sp|Q9Y266|NUDC_HUMAN,tr|A0A0A0MSS4|A0A0A0MSS4_HUMAN,tr|A0A0A0MSU9|A0A0A0MSU9_HUMAN" 3 2212.1433 2.24 85970 17747 4 2212.149334 554.0431 Nuclear migration protein nudC OS=Homo sapiens OX=9606 GN=NUDC PE=1 SV=1 4.25 2892.7 - 1.08E+06 - - - 2.7155 - 2.644 0.432 - 156 1 2 1 0.006 18 0 0 0 2.38E+07 1.07E+07 - - - 3.3175 1 221125_WJC_METTL3_EV_vs_WT_F06.17749.17749.4 9.99E-09 15/102 K.FAASGGFLHHMAGLSSSK.L "sp|Q9BY77|PDIP3_HUMAN,tr|F6VRR5|F6VRR5_HUMAN,tr|F8WCX5|F8WCX5_HUMAN,tr|Q8WUT1|Q8WUT1_HUMAN" 4 1803.8726 1.5 85971 17749 4 1803.873716 451.9754 Polymerase delta-interacting protein 3 OS=Homo sapiens OX=9606 GN=POLDIP3 PE=1 SV=2 8.76 2892.9 - 1.33E+07 - - - 0.5976 - 3.225 0.608 - 194.7 1 2 0 0.0011 18 0 0 0 2.28E+08 1.52E+08 - - - 4.9188 1 221125_WJC_METTL3_EV_vs_WT_F06.17750.17750.4 0.000162 20/102 K.FAASGGFLHHMAGLSSSK[136.11].L "sp|Q9BY77|PDIP3_HUMAN,tr|F6VRR5|F6VRR5_HUMAN,tr|F8WCX5|F8WCX5_HUMAN,tr|Q8WUT1|Q8WUT1_HUMAN" 4 1811.8868 1.49 85972 17750 4 1811.885743 453.979 Polymerase delta-interacting protein 3 OS=Homo sapiens OX=9606 GN=POLDIP3 PE=1 SV=2 8.76 2892.9 - 9.43E+06 - - - -0.6043 - 4.002 0.579 - 366.6 1 2 0 -0.0011 18 0 0 0 2.34E+08 1.57E+08 - - - 4.7404 0.8677 221125_WJC_METTL3_EV_vs_WT_F06.17751.17751.2 0.0448 22-Dec F.FDNISC[160.03]DDNRER.R "sp|Q8ND56|LS14A_HUMAN,tr|A0A096LP11|A0A096LP11_HUMAN,tr|A0A140TA76|A0A140TA76_HUMAN,tr|A0A0G2JQ95|A0A0G2JQ95_HUMAN" 4 1539.6372 1.18 85973 17751 2 1539.635455 770.8259 Protein LSM14 homolog A OS=Homo sapiens OX=9606 GN=LSM14A PE=1 SV=3 4.23 2893.1 - 1.62E+06 - - - -1.1457 - 1.873 0.482 - 237.5 1 1 1 -0.0018 12 0 0 0 8.64E+07 7.31E+07 - - - 4.2517 1 221125_WJC_METTL3_EV_vs_WT_F06.17754.17754.3 1.53E-07 16/52 K.HWPFQVINDGDKPK.V "sp|P0DMV8|HS71A_HUMAN,sp|P0DMV9|HS71B_HUMAN,tr|A0A0G2JIW1|A0A0G2JIW1_HUMAN" 3 1679.842 0.12 85976 17754 3 1679.845627 560.9546 Heat shock 70 kDa protein 1A OS=Homo sapiens OX=9606 GN=HSPA1A PE=1 SV=1 6.75 2893.4 - 691978 - - - 2.1651 - 3.34 0.547 - 263.6 1 2 0 0.0036 14 0 0 0 1.86E+07 1.59E+08 - - - 7.8424 1 221125_WJC_METTL3_EV_vs_WT_F06.17758.17758.2 2.89E-16 21/40 K.FGVSSSSSGPSQTLTSTGNFK[136.11].F sp|P49790|NU153_HUMAN 1 2082.9949 2.94 85978 17758 2 2082.996437 1042.5047 Nuclear pore complex protein Nup153 OS=Homo sapiens OX=9606 GN=NUP153 PE=1 SV=2 8.75 2893.9 - 1.22E+06 - - - 0.7244 - 4.344 0.753 - 1311.4 1 2 0 0.0015 21 0 0 0 3.21E+07 1.09E+07 - - - 8.2133 1 221125_WJC_METTL3_EV_vs_WT_F06.17771.17771.3 2.52E-08 17/68 K.FAASGGFLHHMAGLSSSK.L "sp|Q9BY77|PDIP3_HUMAN,tr|F6VRR5|F6VRR5_HUMAN,tr|F8WCX5|F8WCX5_HUMAN,tr|Q8WUT1|Q8WUT1_HUMAN" 4 1803.8726 1.46 85986 17771 3 1803.868152 602.2982 Polymerase delta-interacting protein 3 OS=Homo sapiens OX=9606 GN=POLDIP3 PE=1 SV=2 8.76 2895.6 - 8.35E+06 - - - -2.4869 - 3.565 0.634 - 332.9 1 2 0 -0.0045 18 0 0 0 2.35E+08 1.61E+08 - - - 8.7726 1 221125_WJC_METTL3_EV_vs_WT_F06.17772.17772.3 6.16E-10 16/68 K.FAASGGFLHHMAGLSSSK[136.11].L "sp|Q9BY77|PDIP3_HUMAN,tr|F6VRR5|F6VRR5_HUMAN,tr|F8WCX5|F8WCX5_HUMAN,tr|Q8WUT1|Q8WUT1_HUMAN" 4 1811.8868 1.46 85987 17772 3 1811.883481 604.9696 Polymerase delta-interacting protein 3 OS=Homo sapiens OX=9606 GN=POLDIP3 PE=1 SV=2 8.76 2895.6 - 5.01E+06 - - - -1.8528 - 3.257 0.601 - 257.1 1 2 0 -0.0034 18 0 0 0 2.37E+08 1.62E+08 - - - 8.18 1 221125_WJC_METTL3_EV_vs_WT_F06.17773.17773.3 1.08E-07 14/56 K.QISNLQQSISDAEQR.G sp|P04264|K2C1_HUMAN 1 1715.8438 4177.07 85988 17773 3 1715.846021 572.9552 "Keratin, type II cytoskeletal 1 OS=Homo sapiens OX=9606 GN=KRT1 PE=1 SV=6" 4.37 2895.7 - 9.48E+06 - - - 1.2705 - 3.073 0.537 - 261 1 2 0 0.0022 15 0 0 0 2.60E+10 6.22E+06 - - - 7.4558 1 221125_WJC_METTL3_EV_vs_WT_F06.17774.17774.2 9.69E-10 15/28 K.QISNLQQSISDAEQR.G sp|P04264|K2C1_HUMAN 1 1715.8438 999 85989 17774 2 1715.843019 858.9292 "Keratin, type II cytoskeletal 1 OS=Homo sapiens OX=9606 GN=KRT1 PE=1 SV=6" 4.37 2895.7 - 5.64E+06 - - - -0.4791 - 3.104 0.591 - 853.9 1 2 0 -0.0008 15 0 0 0 2.29E+10 0.00E+00 - - - 6.1906 0.9998 221125_WJC_METTL3_EV_vs_WT_F06.17785.17785.4 1.16E-06 17/90 R.LLIYKVSNRFSGVPDR.F sp|A0A075B6R9|KVD24_HUMAN 1 1863.0367 235.51 85996 17785 4 1863.038464 466.7664 Probable non-functional immunoglobulin kappa variable 2D-24 OS=Homo sapiens OX=9606 GN=IGKV2D-24 PE=1 SV=1 9.99 2897.1 - 1.53E+06 - - - 0.9646 - 2.652 0.454 - 201.1 1 2 2 0.0018 16 0 0 0 5.89E+07 2.50E+05 - - - 3.5207 0.9998 221125_WJC_METTL3_EV_vs_WT_F06.17787.17787.3 4.72E-07 15/52 R.SK[136.11]ESVPEFPLSPPK[136.11].K "sp|P16949|STMN1_HUMAN,tr|A2A2D0|A2A2D0_HUMAN" 2 1556.8421 0.42 85998 17787 3 1556.842631 519.9546 Stathmin OS=Homo sapiens OX=9606 GN=STMN1 PE=1 SV=3 5.86 2897.4 - 664803 - - - 0.3347 - 2.407 0.49 - 148.3 1 2 1 0.0005 14 0 0 0 2.00E+07 4.71E+07 - - - 6.3372 0.9994 221125_WJC_METTL3_EV_vs_WT_F06.17790.17790.3 3.72E-07 14/76 R.ESTGAQVQVAGDMLPNSTER.A "sp|P57721|PCBP3_HUMAN,sp|Q15366|PCBP2_HUMAN,sp|Q15365|PCBP1_HUMAN,tr|E9PFP8|E9PFP8_HUMAN,tr|J3QT27|J3QT27_HUMAN,tr|F8VZX2|F8VZX2_HUMAN,tr|F8W0G4|F8W0G4_HUMAN,tr|F8VXH9|F8VXH9_HUMAN,tr|H3BRU6|H3BRU6_HUMAN" 9 2088.9746 0.45 85999 17790 3 2088.963226 697.3321 Poly(rC)-binding protein 3 OS=Homo sapiens OX=9606 GN=PCBP3 PE=1 SV=2 4.14 2897.8 - 6.69E+06 - - - -5.4433 - 2.585 0.511 - 110.7 1 2 0 -0.0114 20 0 0 0 2.07E+08 4.63E+08 - - - 6.5381 0.9972 221125_WJC_METTL3_EV_vs_WT_F06.17793.17793.3 0.00516 Jul-60 K.EKPSEDMESNTFFDPR.V sp|O43395|PRPF3_HUMAN 1 1927.8258 2.24 86001 17793 3 1927.820402 643.6159 U4\U6 small nuclear ribonucleoprotein Prp3 OS=Homo sapiens OX=9606 GN=PRPF3 PE=1 SV=2 4.18 2898 - 2.83E+06 - - - -2.8037 - 1.481 0.346 - 30 1 2 0 -0.0054 16 0 0 0 3.74E+08 1.67E+08 - - - 3.4037 0.9998 221125_WJC_METTL3_EV_vs_WT_F06.17796.17796.3 0.000762 Nov-60 R.K[136.11]QSLPATSIPTPASFK[136.11].F sp|P49792|RBP2_HUMAN 1 1687.948 1.05 86004 17796 3 1687.945362 563.6566 E3 SUMO-protein ligase RanBP2 OS=Homo sapiens OX=9606 GN=RANBP2 PE=1 SV=2 10 2898.3 - 1.10E+06 - - - -1.5463 - 2.107 0.412 - 89.2 1 2 0 -0.0026 16 0 0 0 4.95E+07 4.72E+07 - - - 5.0449 1 221125_WJC_METTL3_EV_vs_WT_F06.17799.17799.2 4.14E-07 14/24 R.TTPSYVAFTDTER[166.11].L "sp|P48741|HSP77_HUMAN,sp|P54652|HSP72_HUMAN,sp|P0DMV8|HS71A_HUMAN,sp|P34931|HS71L_HUMAN,sp|P11142|HSP7C_HUMAN,sp|P0DMV9|HS71B_HUMAN,sp|P17066|HSP76_HUMAN,tr|E9PQQ4|E9PQQ4_HUMAN,tr|E9PNE6|E9PNE6_HUMAN,tr|E9PKE3|E9PKE3_HUMAN,tr|E9PLF4|E9PLF4_HUMAN,tr|Q53FA3|Q53FA3_HUMAN,tr|E9PI65|E9PI65_HUMAN,tr|E9PK54|E9PK54_HUMAN,tr|E9PN25|E9PN25_HUMAN,tr|E9PPY6|E9PPY6_HUMAN,tr|E9PQK7|E9PQK7_HUMAN,tr|A0A0G2JIW1|A0A0G2JIW1_HUMAN" 18 1496.7023 0.1 86005 17799 2 1496.703255 749.3584 Putative heat shock 70 kDa protein 7 OS=Homo sapiens OX=9606 GN=HSPA7 PE=5 SV=2 4.37 2898.7 - 1.72E+06 - - - 0.6655 - 2.501 0.589 - 727.5 1 2 0 0.001 13 0 0 0 2.01E+07 2.09E+08 - - - 5.7438 1 221125_WJC_METTL3_EV_vs_WT_F06.17807.17807.3 4.30E-06 17/60 R.KQSLPATSIPTPASFK.F sp|P49792|RBP2_HUMAN 1 1671.9196 1 86010 17807 3 1671.918222 558.3138 E3 SUMO-protein ligase RanBP2 OS=Homo sapiens OX=9606 GN=RANBP2 PE=1 SV=2 10 2899.7 - 1.38E+06 - - - -0.8075 - 3.205 0.487 - 389.2 1 2 0 -0.0013 16 0 0 0 5.21E+07 5.19E+07 - - - 6.9577 0.9995 221125_WJC_METTL3_EV_vs_WT_F06.17808.17808.2 0.000385 Dec-32 K.VSYIPDEQIAQGPENGR.R sp|Q9NZI8|IF2B1_HUMAN 1 1871.9014 0.76 86011 17808 2 1871.902908 936.958 Insulin-like growth factor 2 mRNA-binding protein 1 OS=Homo sapiens OX=9606 GN=IGF2BP1 PE=1 SV=2 4.14 2899.8 - 1.04E+06 - - - 0.8291 - 1.762 0.378 - 257.7 1 2 0 0.0016 17 0 0 0 2.19E+07 2.89E+07 - - - 3.2251 0.9867 221125_WJC_METTL3_EV_vs_WT_F06.17817.17817.2 0.00584 16-Sep Q.QSISDAEQR.G sp|P04264|K2C1_HUMAN 1 1032.4836 68.86 86017 17817 2 1032.483657 517.2491 "Keratin, type II cytoskeletal 1 OS=Homo sapiens OX=9606 GN=KRT1 PE=1 SV=6" 4.37 2901 - 1.48E+06 - - - 0.0533 - 2.016 0.387 - 261.5 1 1 0 0.0001 9 0 0 0 5.06E+07 7.34E+05 - - - 3.9277 0.9999 221125_WJC_METTL3_EV_vs_WT_F06.17822.17822.3 2.19E-08 21/72 K.LQTLVSEQPNKDVVEQMEK.C sp|Q86UP2|KTN1_HUMAN 1 2214.1202 1.54 86019 17822 3 2214.119463 739.0473 Kinectin OS=Homo sapiens OX=9606 GN=KTN1 PE=1 SV=1 4.41 2901.6 - 2.05E+06 - - - -0.3324 - 3.504 0.503 - 604.8 1 2 1 -0.0007 19 0 0 0 5.84E+07 3.80E+07 - - - 7.2283 1 221125_WJC_METTL3_EV_vs_WT_F06.17825.17825.2 1.74E-05 17/28 K.NQVAMNPTNTVFDAK[136.11].R "sp|P11142|HSP7C_HUMAN,tr|E9PQQ4|E9PQQ4_HUMAN,tr|E9PNE6|E9PNE6_HUMAN,tr|E9PKE3|E9PKE3_HUMAN,tr|E9PLF4|E9PLF4_HUMAN,tr|E9PK54|E9PK54_HUMAN,tr|E9PN25|E9PN25_HUMAN,tr|E9PPY6|E9PPY6_HUMAN,tr|E9PQK7|E9PQK7_HUMAN" 9 1656.8021 0.08 86022 17825 2 1656.795853 829.4083 Heat shock cognate 71 kDa protein OS=Homo sapiens OX=9606 GN=HSPA8 PE=1 SV=1 5.84 2901.9 - 2.40E+06 - - - -3.7741 - 3.257 0.636 - 690.2 1 2 0 -0.0063 15 0 0 0 1.38E+07 1.67E+08 - - - 6.6396 0.9981 221125_WJC_METTL3_EV_vs_WT_F06.17828.17828.3 1.90E-05 16/72 Q.SSELVSWADGGQHSSIHPA.- "sp|O00746|NDKM_HUMAN,tr|Q4TT34|Q4TT34_HUMAN,tr|A0A087WVT9|A0A087WVT9_HUMAN" 3 1963.9024 - 86024 17828 3 1963.900433 655.6414 "Nucleoside diphosphate kinase, mitochondrial OS=Homo sapiens OX=9606 GN=NME4 PE=1 SV=1" 5.14 2902.3 - 4.82E+06 - - - -1.0107 - 3.591 0.495 - 225.6 1 1 0 -0.002 19 0 0 0 - - - - - 7.1991 1 221125_WJC_METTL3_EV_vs_WT_F06.17830.17830.3 1.79E-07 16/68 K.YVHYEIDAC[160.03]MDSEAPGSK[136.11].D "sp|Q86U44|MTA70_HUMAN,tr|H0YFV6|H0YFV6_HUMAN" 2 2078.8805 0.01 86025 17830 3 2079.878592 693.9674 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 4.31 2902.5 - 6.33E+06 - - - 480.1142 - 3.281 0.661 - 266.7 1 2 0 0.9981 18 0 0 0 6.77E+06 4.78E+08 - - - 8.5916 0.9999 221125_WJC_METTL3_EV_vs_WT_F06.17831.17831.3 1.74E-06 14/60 K.GSVDHENWVSNYNALR.A sp|Q8WVQ1|CANT1_HUMAN 1 1859.8551 15.62 86026 17831 3 1859.850698 620.959 Soluble calcium-activated nucleotidase 1 OS=Homo sapiens OX=9606 GN=CANT1 PE=1 SV=1 5.32 2902.6 - 2.12E+06 - - - -2.3529 - 2.342 0.517 - 203.2 1 2 0 -0.0044 16 0 0 0 5.08E+07 3.25E+06 - - - 6.4864 1 221125_WJC_METTL3_EV_vs_WT_F06.17840.17840.4 1.73E-10 25/120 K.LTALDYHNPAGFNC[160.03]K[136.11]DETEFR[166.11].N "sp|Q9Y224|RTRAF_HUMAN,tr|G3V4C6|G3V4C6_HUMAN,tr|G3V4E7|G3V4E7_HUMAN" 3 2515.1557 0.64 86032 17840 4 2515.146883 629.7962 "RNA transcription, translation and transport factor protein OS=Homo sapiens OX=9606 GN=RTRAF PE=1 SV=1" 4.75 2903.6 - 6.45E+06 - - - -3.5028 - 4.37 0.661 - 578 1 2 1 -0.0088 21 0 0 0 9.14E+07 1.42E+08 - - - 5.4645 1 221125_WJC_METTL3_EV_vs_WT_F06.17845.17845.4 1.58E-06 25/108 R.LLEAQIATGGVIDPVHSHR.V "sp|P58107|EPIPL_HUMAN,sp|P58107|EPIPL_HUMAN,sp|P58107|EPIPL_HUMAN,sp|P58107|EPIPL_HUMAN,sp|P58107|EPIPL_HUMAN,sp|P58107|EPIPL_HUMAN,sp|Q15149|PLEC_HUMAN,tr|A0A075B730|A0A075B730_HUMAN,tr|A0A075B730|A0A075B730_HUMAN,tr|A0A075B730|A0A075B730_HUMAN,tr|A0A075B730|A0A075B730_HUMAN,tr|A0A075B730|A0A075B730_HUMAN,tr|A0A075B730|A0A075B730_HUMAN,tr|H0YDN1|H0YDN1_HUMAN" 14 2012.0803 1.89 86035 17845 4 2012.077293 504.0274 Epiplakin OS=Homo sapiens OX=9606 GN=EPPK1 PE=1 SV=3 5.99 2904.1 - 2.83E+06 - - - -1.5059 - 2.73 0.556 - 199 1 2 0 -0.003 19 0 0 0 8.96E+07 4.73E+07 - - - 4.4043 1 221125_WJC_METTL3_EV_vs_WT_F06.17851.17851.3 4.35E-07 25/72 R.LLEAQIATGGVIDPVHSHR[166.11].V "sp|P58107|EPIPL_HUMAN,sp|P58107|EPIPL_HUMAN,sp|P58107|EPIPL_HUMAN,sp|P58107|EPIPL_HUMAN,sp|P58107|EPIPL_HUMAN,sp|P58107|EPIPL_HUMAN,sp|Q15149|PLEC_HUMAN,tr|A0A075B730|A0A075B730_HUMAN,tr|A0A075B730|A0A075B730_HUMAN,tr|A0A075B730|A0A075B730_HUMAN,tr|A0A075B730|A0A075B730_HUMAN,tr|A0A075B730|A0A075B730_HUMAN,tr|A0A075B730|A0A075B730_HUMAN,tr|H0YDN1|H0YDN1_HUMAN" 14 2022.0886 1.69 86039 17851 3 2022.085688 675.0368 Epiplakin OS=Homo sapiens OX=9606 GN=EPPK1 PE=1 SV=3 5.99 2904.8 - 1.21E+06 - - - -1.4366 - 3.708 0.579 - 373 1 2 0 -0.0029 19 0 0 0 3.05E+07 1.80E+07 - - - 8.2141 1 221125_WJC_METTL3_EV_vs_WT_F06.17852.17852.3 4.80E-11 27/72 R.LLEAQIATGGVIDPVHSHR.V "sp|P58107|EPIPL_HUMAN,sp|P58107|EPIPL_HUMAN,sp|P58107|EPIPL_HUMAN,sp|P58107|EPIPL_HUMAN,sp|P58107|EPIPL_HUMAN,sp|P58107|EPIPL_HUMAN,sp|Q15149|PLEC_HUMAN,tr|A0A075B730|A0A075B730_HUMAN,tr|A0A075B730|A0A075B730_HUMAN,tr|A0A075B730|A0A075B730_HUMAN,tr|A0A075B730|A0A075B730_HUMAN,tr|A0A075B730|A0A075B730_HUMAN,tr|A0A075B730|A0A075B730_HUMAN,tr|H0YDN1|H0YDN1_HUMAN" 14 2012.0803 1.69 86040 17852 3 2012.076686 671.7007 Epiplakin OS=Homo sapiens OX=9606 GN=EPPK1 PE=1 SV=3 5.99 2905 - 1.23E+06 - - - -1.8076 - 4.007 0.638 - 881.1 1 2 0 -0.0036 19 0 0 0 3.05E+07 1.80E+07 - - - 9.0622 1 221125_WJC_METTL3_EV_vs_WT_F06.17859.17859.4 2.69E-07 22/120 K.LTALDYHNPAGFNC[160.03]KDETEFR.N "sp|Q9Y224|RTRAF_HUMAN,tr|G3V4C6|G3V4C6_HUMAN,tr|G3V4E7|G3V4E7_HUMAN" 3 2497.1332 0.64 86044 17859 4 2497.131819 625.2906 "RNA transcription, translation and transport factor protein OS=Homo sapiens OX=9606 GN=RTRAF PE=1 SV=1" 4.75 2905.7 - 9.33E+06 - - - -0.5622 - 3.973 0.617 - 380.2 1 2 1 -0.0014 21 0 0 0 9.09E+07 1.41E+08 - - - 5.0521 1 221125_WJC_METTL3_EV_vs_WT_F06.17860.17860.2 3.74E-08 19/38 R.ESTGAQVQVAGDMLPNSTER[166.11].A "sp|P57721|PCBP3_HUMAN,sp|Q15366|PCBP2_HUMAN,sp|Q15365|PCBP1_HUMAN,tr|E9PFP8|E9PFP8_HUMAN,tr|J3QT27|J3QT27_HUMAN,tr|F8VZX2|F8VZX2_HUMAN,tr|F8W0G4|F8W0G4_HUMAN,tr|F8VXH9|F8VXH9_HUMAN,tr|H3BRU6|H3BRU6_HUMAN" 9 2098.9829 1.32 86045 17860 2 2098.976615 1050.4987 Poly(rC)-binding protein 3 OS=Homo sapiens OX=9606 GN=PCBP3 PE=1 SV=2 4.14 2905.8 - 3.29E+06 - - - -2.9786 - 3.131 0.572 - 843.9 1 2 0 -0.0063 20 0 0 0 1.89E+08 1.44E+08 - - - 6.0699 0.9985 221125_WJC_METTL3_EV_vs_WT_F06.17861.17861.4 0.00012 20/90 K.LEQMPSK[136.11]EDAIEHFMK[136.11].L "sp|P09874|PARP1_HUMAN,tr|A0A7I2V3E1|A0A7I2V3E1_HUMAN" 2 1947.9405 1.02 86046 17861 4 1947.932745 487.9924 Poly [ADP-ribose] polymerase 1 OS=Homo sapiens OX=9606 GN=PARP1 PE=1 SV=4 4.83 2905.9 - 1.40E+06 - - - -3.9914 - 2.995 0.45 - 325.4 1 2 1 -0.0078 16 0 0 0 6.13E+07 6.00E+07 - - - 3.5271 1 221125_WJC_METTL3_EV_vs_WT_F06.17868.17868.3 1.20E-13 31/80 K.LTALDYHNPAGFNC[160.03]K[136.11]DETEFR[166.11].N "sp|Q9Y224|RTRAF_HUMAN,tr|G3V4C6|G3V4C6_HUMAN,tr|G3V4E7|G3V4E7_HUMAN" 3 2515.1557 1.38 86050 17868 3 2515.155958 839.3925 "RNA transcription, translation and transport factor protein OS=Homo sapiens OX=9606 GN=RTRAF PE=1 SV=1" 4.75 2906.8 - 1.73E+06 - - - 0.1054 - 5.739 0.739 - 1487.4 1 2 1 0.0003 21 0 0 0 8.42E+07 6.09E+07 - - - 10.9681 0.9994 221125_WJC_METTL3_EV_vs_WT_F06.17869.17869.3 0.00704 13/76 R.QQVAFYGQTLGQAQAHSQEQ.- sp|Q96I24|FUBP3_HUMAN 1 2218.0403 - 86051 17869 3 2218.03946 740.354 Far upstream element-binding protein 3 OS=Homo sapiens OX=9606 GN=FUBP3 PE=1 SV=2 5.24 2906.9 - 1.17E+06 - - - -0.3828 - 2.524 0.255 - 169 1 2 0 -0.0008 20 0 0 0 - - - - - 3.6289 0.9999 221125_WJC_METTL3_EV_vs_WT_F06.17873.17873.4 1.19E-08 22/90 K.LEQMPSKEDAIEHFMK.L "sp|P09874|PARP1_HUMAN,tr|A0A7I2V3E1|A0A7I2V3E1_HUMAN" 2 1931.9121 1.02 86053 17873 4 1931.910616 483.9853 Poly [ADP-ribose] polymerase 1 OS=Homo sapiens OX=9606 GN=PARP1 PE=1 SV=4 4.83 2907.5 - 1.96E+06 - - - -0.7785 - 4.18 0.543 - 388.4 1 2 1 -0.0015 16 0 0 0 6.13E+07 6.00E+07 - - - 4.4557 1 221125_WJC_METTL3_EV_vs_WT_F06.17874.17874.2 1.20E-09 17/28 K.NQVAMNPTNTVFDAK.R "sp|P11142|HSP7C_HUMAN,tr|E9PQQ4|E9PQQ4_HUMAN,tr|E9PNE6|E9PNE6_HUMAN,tr|E9PKE3|E9PKE3_HUMAN,tr|E9PLF4|E9PLF4_HUMAN,tr|E9PK54|E9PK54_HUMAN,tr|E9PN25|E9PN25_HUMAN,tr|E9PPY6|E9PPY6_HUMAN,tr|E9PQK7|E9PQK7_HUMAN" 9 1648.7879 0.08 86054 17874 2 1648.784447 825.4012 Heat shock cognate 71 kDa protein OS=Homo sapiens OX=9606 GN=HSPA8 PE=1 SV=1 5.84 2907.6 - 1.28E+06 - - - -2.0979 - 3.176 0.654 - 791.9 1 2 0 -0.0035 15 0 0 0 1.38E+07 1.63E+08 - - - 6.7115 1 221125_WJC_METTL3_EV_vs_WT_F06.17875.17875.3 2.63E-07 21/48 R.HLMHLELDISDSK.L "sp|P16435|NCPR_HUMAN,tr|H0Y4R2|H0Y4R2_HUMAN,tr|E7EMD0|E7EMD0_HUMAN" 3 1536.7606 2.16 86055 17875 3 1536.762443 513.2608 NADPH--cytochrome P450 reductase OS=Homo sapiens OX=9606 GN=POR PE=1 SV=2 5.21 2907.7 - 614811 - - - 1.1811 - 3.762 0.585 - 774.8 1 2 0 0.0018 13 0 0 0 2.56E+07 1.18E+07 - - - 8.654 1 221125_WJC_METTL3_EV_vs_WT_F06.17879.17879.3 8.47E-13 20/76 K.FYQTSVESVDFANAPEESRK.K sp|P29508|SPB3_HUMAN 1 2303.0706 999 86057 17879 3 2303.068039 768.6975 Serpin B3 OS=Homo sapiens OX=9606 GN=SERPINB3 PE=1 SV=2 4.41 2908.2 - 1.82E+06 - - - -1.1146 - 3.795 0.663 - 404.9 1 2 0 -0.0026 20 0 0 0 3.36E+07 0.00E+00 - - - 9.1666 0.9522 221125_WJC_METTL3_EV_vs_WT_F06.17880.17880.3 0.0315 Oct-52 R.KESEFDDEPK[136.11]FMSK[136.11].V "sp|Q9Y2W1|TR150_HUMAN,tr|A0A3B3ITZ9|A0A3B3ITZ9_HUMAN" 2 1731.7997 - 86058 17880 3 1731.798642 578.2738 Thyroid hormone receptor-associated protein 3 OS=Homo sapiens OX=9606 GN=THRAP3 PE=1 SV=2 4.51 2908.2 - 2.38E+06 - - - -0.5838 - 1.717 0.16 - 130.1 1 2 1 -0.001 14 0 0 0 - - - - - 1.7602 1 221125_WJC_METTL3_EV_vs_WT_F06.17881.17881.3 3.33E-06 18/60 R.EEMEQLFHDDQGGVTR[166.11].W "sp|Q15643|TRIPB_HUMAN,tr|H0YJ97|H0YJ97_HUMAN" 2 1899.8297 1.32 86059 17881 3 1899.829975 634.2838 Thyroid receptor-interacting protein 11 OS=Homo sapiens OX=9606 GN=TRIP11 PE=1 SV=3 4.17 2908.4 - 1.35E+06 - - - 0.1653 - 3.191 0.605 - 638.1 1 2 0 0.0003 16 0 0 0 2.13E+07 1.61E+07 - - - 8.2623 1 221125_WJC_METTL3_EV_vs_WT_F06.17884.17884.3 2.52E-07 21/72 K.ELTYQNTDLSEIKEEEQVK.S sp|Q32MZ4|LRRF1_HUMAN 1 2295.1118 0.53 86062 17884 3 2295.118061 766.0445 Leucine-rich repeat flightless-interacting protein 1 OS=Homo sapiens OX=9606 GN=LRRFIP1 PE=1 SV=2 4.14 2908.7 - 827934 - - - 2.7271 - 4.338 0.606 - 449.2 1 2 1 0.0063 19 0 0 0 8.88E+06 1.67E+07 - - - 8.8997 1 221125_WJC_METTL3_EV_vs_WT_F06.17892.17892.3 0.00065 16/64 R.TFNTSTGGLLLPSDTKR.S "sp|P12956|XRCC6_HUMAN,tr|B1AHC9|B1AHC9_HUMAN" 2 1806.9476 0.91 86068 17892 3 1806.949521 603.3231 X-ray repair cross-complementing protein 6 OS=Homo sapiens OX=9606 GN=XRCC6 PE=1 SV=2 8.41 2909.5 - 2.08E+06 - - - 1.0753 - 2.826 0.469 - 225.1 1 2 0 0.0019 17 0 0 0 3.40E+07 3.76E+07 - - - 6.3928 1 221125_WJC_METTL3_EV_vs_WT_F06.17893.17893.3 2.56E-08 15/64 R.TFNTSTGGLLLPSDTK[136.11]R[166.11].S "sp|P12956|XRCC6_HUMAN,tr|B1AHC9|B1AHC9_HUMAN" 2 1824.97 0.9 86069 17893 3 1824.971569 609.3306 X-ray repair cross-complementing protein 6 OS=Homo sapiens OX=9606 GN=XRCC6 PE=1 SV=2 8.41 2909.6 - 2.07E+06 - - - 0.8334 - 3.151 0.484 - 219.8 1 2 0 0.0015 17 0 0 0 3.57E+07 3.97E+07 - - - 6.8352 1 221125_WJC_METTL3_EV_vs_WT_F06.17899.17899.3 1.81E-10 26/84 R.IVHSLDYYNTC[160.03]EYPNEDEMPNR.C "sp|Q9BXP5|SRRT_HUMAN,tr|H7C3A1|H7C3A1_HUMAN" 2 2758.1639 1.3 86073 17899 3 2758.164784 920.3953 Serrate RNA effector molecule homolog OS=Homo sapiens OX=9606 GN=SRRT PE=1 SV=1 4.17 2910.5 - 1.77E+06 - - - 0.3093 - 4.394 0.756 - 681.6 1 2 0 0.0009 22 0 0 0 2.48E+07 1.91E+07 - - - 10.4778 0.9999 221125_WJC_METTL3_EV_vs_WT_F06.17900.17900.3 0.000213 20/48 R.HLMHLELDISDSK[136.11].L "sp|P16435|NCPR_HUMAN,tr|H0Y4R2|H0Y4R2_HUMAN,tr|E7EMD0|E7EMD0_HUMAN" 3 1544.7748 2.19 86074 17900 3 1544.779139 515.9322 NADPH--cytochrome P450 reductase OS=Homo sapiens OX=9606 GN=POR PE=1 SV=2 5.21 2910.6 - 859089 - - - 2.7907 - 3.636 0.47 - 778.2 1 2 0 0.0043 13 0 0 0 2.48E+07 1.13E+07 - - - 7.2788 1 221125_WJC_METTL3_EV_vs_WT_F06.17902.17902.3 1.29E-06 17/60 R.KPIDYTVLDDVGHGVK.W "sp|Q8IZP0|ABI1_HUMAN,tr|A0A0A0MRT6|A0A0A0MRT6_HUMAN,tr|B6VEX4|B6VEX4_HUMAN" 3 1754.9203 1.62 86076 17902 3 1754.922789 585.9807 Abl interactor 1 OS=Homo sapiens OX=9606 GN=ABI1 PE=1 SV=4 5.3 2910.8 - 1.18E+06 - - - 1.4183 - 3.138 0.5 - 606.3 1 2 0 0.0025 16 0 0 0 2.30E+07 1.42E+07 - - - 7.0481 1 221125_WJC_METTL3_EV_vs_WT_F06.17903.17903.3 2.91E-11 19/72 K.ELTYQNTDLSEIK[136.11]EEEQVK[136.11].S sp|Q32MZ4|LRRF1_HUMAN 1 2311.1402 0.53 86077 17903 3 2311.141943 771.3873 Leucine-rich repeat flightless-interacting protein 1 OS=Homo sapiens OX=9606 GN=LRRFIP1 PE=1 SV=2 4.14 2910.9 - 1.12E+06 - - - 0.7533 - 3.741 0.648 - 326.3 1 2 1 0.0017 19 0 0 0 8.88E+06 1.67E+07 - - - 9.0055 1 221125_WJC_METTL3_EV_vs_WT_F06.17906.17906.4 3.13E-10 21/90 R.KPIDYTVLDDVGHGVK.W "sp|Q8IZP0|ABI1_HUMAN,tr|A0A0A0MRT6|A0A0A0MRT6_HUMAN,tr|B6VEX4|B6VEX4_HUMAN" 3 1754.9203 0.52 86080 17906 4 1754.923462 439.7374 Abl interactor 1 OS=Homo sapiens OX=9606 GN=ABI1 PE=1 SV=4 5.3 2911.2 - 654685 - - - 1.8018 - 3.611 0.531 - 608.5 1 2 0 0.0032 16 0 0 0 9.25E+06 1.78E+07 - - - 4.2992 0.9962 221125_WJC_METTL3_EV_vs_WT_F06.17907.17907.3 0.000909 Jul-32 K.FYVHNDIFR[166.11].Y "sp|Q13283|G3BP1_HUMAN,tr|A0A7I2V5M7|A0A7I2V5M7_HUMAN,tr|A0A7P0P2U7|A0A7P0P2U7_HUMAN,tr|A0A7I2YQU8|A0A7I2YQU8_HUMAN,tr|A0A7I2V651|A0A7I2V651_HUMAN,tr|A0A7I2YQN9|A0A7I2YQN9_HUMAN,tr|A0A7I2V2V1|A0A7I2V2V1_HUMAN" 7 1219.6014 1.24 86081 17907 3 1219.599666 407.5411 Ras GTPase-activating protein-binding protein 1 OS=Homo sapiens OX=9606 GN=G3BP1 PE=1 SV=1 6.74 2911.4 - 386718 - - - -1.3914 - 1.552 0.239 - 64.6 1 2 0 -0.0017 9 0 0 0 7.68E+06 6.18E+06 - - - 2.5288 1 221125_WJC_METTL3_EV_vs_WT_F06.17910.17910.2 4.96E-10 13/32 R.NVSSFPDDATSPLQENR.N "sp|P52292|IMA1_HUMAN,tr|J3QLL0|J3QLL0_HUMAN,tr|J3KS65|J3KS65_HUMAN,tr|A0A7I2V3Z3|A0A7I2V3Z3_HUMAN,tr|A0A7I2YQE1|A0A7I2YQE1_HUMAN,tr|A0A7I2V487|A0A7I2V487_HUMAN,tr|A0A7I2V351|A0A7I2V351_HUMAN" 7 1875.8599 0.96 86084 17910 2 1875.865475 938.9372 Importin subunit alpha-1 OS=Homo sapiens OX=9606 GN=KPNA2 PE=1 SV=1 4.03 2911.8 - 256296 - - - 2.98 - 2.709 0.652 - 395.2 1 2 0 0.0056 17 0 0 0 3.21E+06 3.35E+06 - - - 6.3051 1 221125_WJC_METTL3_EV_vs_WT_F06.17914.17914.3 3.34E-07 15/60 R.EEMEQLFHDDQGGVTR.W "sp|Q15643|TRIPB_HUMAN,tr|H0YJ97|H0YJ97_HUMAN" 2 1889.8214 1.31 86086 17914 3 1889.824327 630.9477 Thyroid receptor-interacting protein 11 OS=Homo sapiens OX=9606 GN=TRIP11 PE=1 SV=3 4.17 2912.2 - 1.75E+06 - - - 1.5536 - 2.967 0.518 - 386.2 1 2 0 0.0029 16 0 0 0 2.13E+07 1.62E+07 - - - 7.1049 0.992 221125_WJC_METTL3_EV_vs_WT_F06.17920.17920.3 0.000752 Nov-72 K.VTQLDPK[136.11]EEEVSLQGINTR[166.11].K sp|Q9Y6W5|WASF2_HUMAN 1 2173.1345 0.79 86092 17920 3 2173.14255 725.3855 Wiskott-Aldrich syndrome protein family member 2 OS=Homo sapiens OX=9606 GN=WASF2 PE=1 SV=3 4.41 2912.9 - 307181 - - - 3.6827 - 2.011 0.362 - 99.2 1 2 1 0.008 19 0 0 0 1.73E+06 2.18E+06 - - - 4.2901 0.9998 221125_WJC_METTL3_EV_vs_WT_F06.17926.17926.3 6.62E-05 13/60 K.LEQMPSK[136.11]EDAIEHFMK[136.11].L "sp|P09874|PARP1_HUMAN,tr|A0A7I2V3E1|A0A7I2V3E1_HUMAN" 2 1947.9405 1.01 86096 17926 3 1947.94149 650.3208 Poly [ADP-ribose] polymerase 1 OS=Homo sapiens OX=9606 GN=PARP1 PE=1 SV=4 4.83 2913.7 - 1.42E+06 - - - 0.498 - 2.416 0.467 - 102.9 1 2 1 0.001 16 0 0 0 2.95E+07 2.91E+07 - - - 6.0097 1 221125_WJC_METTL3_EV_vs_WT_F06.17930.17930.3 2.23E-16 21/96 K.LVQDVANNTNEEAGDGTTTATVLAR.S "sp|P10809|CH60_HUMAN,tr|C9JL25|C9JL25_HUMAN,tr|A0A7I2V2X6|A0A7I2V2X6_HUMAN,tr|A0A7I2YQK6|A0A7I2YQK6_HUMAN,tr|A0A7I2V599|A0A7I2V599_HUMAN,tr|E7EXB4|E7EXB4_HUMAN,tr|A0A7I2YQ71|A0A7I2YQ71_HUMAN,tr|E7ESH4|E7ESH4_HUMAN,tr|A0A7I2V5M1|A0A7I2V5M1_HUMAN,tr|A0A7I2V5K3|A0A7I2V5K3_HUMAN,tr|A0A7I2V369|A0A7I2V369_HUMAN" 11 2559.2413 1.15 86100 17930 3 2559.246682 854.0877 "60 kDa heat shock protein, mitochondrial OS=Homo sapiens OX=9606 GN=HSPD1 PE=1 SV=2" 3.92 2914 - 1.19E+06 - - - 2.1213 - 3.878 0.705 - 532.3 1 2 0 0.0054 25 0 0 0 1.52E+08 1.32E+08 - - - 9.5166 1 221125_WJC_METTL3_EV_vs_WT_F06.17932.17932.2 4.27E-14 16/38 R.FSSC[160.03]GGGGGSFGAGGGFGSR.S sp|P04264|K2C1_HUMAN 1 1764.7274 0.12 86102 17932 2 1764.73086 883.371 "Keratin, type II cytoskeletal 1 OS=Homo sapiens OX=9606 GN=KRT1 PE=1 SV=6" 8.25 2914.2 - 679750 - - - 1.9431 - 3.864 0.771 - 831.2 1 2 0 0.0034 20 0 0 0 6.89E+07 5.99E+08 - - - 8.0578 0.9949 221125_WJC_METTL3_EV_vs_WT_F06.17935.17935.3 1.88E-05 13/72 K.PSTASAVPELATDPELEK[136.11]K[136.11].L "sp|Q86U44|MTA70_HUMAN,tr|B4E349|B4E349_HUMAN,tr|F5H6D8|F5H6D8_HUMAN,tr|H0YFV6|H0YFV6_HUMAN,tr|B4DTN4|B4DTN4_HUMAN" 5 1998.0492 0.04 86105 17935 3 1998.051768 667.0237 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 4.41 2914.6 - 406795 - - - 1.2843 - 2.677 0.472 - 173.9 1 1 0 0.0026 19 0 0 0 3.17E+05 7.85E+06 - - - 6.2208 1 221125_WJC_METTL3_EV_vs_WT_F06.17937.17937.3 3.47E-11 13/88 K.VPLPSADAPNQAEPDVLVEK[136.11]PEK[136.11].V sp|Q8NEN9|PDZD8_HUMAN 1 2458.2926 1.65 86107 17937 3 2458.298501 820.4381 PDZ domain-containing protein 8 OS=Homo sapiens OX=9606 GN=PDZD8 PE=1 SV=1 4.18 2914.8 - 192606 - - - 2.3923 - 3.269 0.574 - 161.3 1 2 0 0.0059 23 0 0 0 3.04E+06 1.84E+06 - - - 7.7166 1 221125_WJC_METTL3_EV_vs_WT_F06.17941.17941.3 1.72E-11 22/84 R.QPYAVSELAGHQTSAESWGTGR.A "sp|P36578|RL4_HUMAN,tr|H3BTP7|H3BTP7_HUMAN,tr|H3BU31|H3BU31_HUMAN" 3 2331.088 1.17 86109 17941 3 2331.091775 778.0366 60S ribosomal protein L4 OS=Homo sapiens OX=9606 GN=RPL4 PE=1 SV=5 5.4 2915.4 - 898320 - - - 1.625 - 4.028 0.542 - 595.5 1 2 0 0.0038 22 0 0 0 1.57E+08 1.35E+08 - - - 7.8849 0.9999 221125_WJC_METTL3_EV_vs_WT_F06.17943.17943.3 6.30E-06 14/84 R.IEPGVSVSLVNPQPSNGHFSTK[136.11].L "sp|Q9P2J5|SYLC_HUMAN,tr|A0A6I8PIV1|A0A6I8PIV1_HUMAN,tr|A0A6I8PRS0|A0A6I8PRS0_HUMAN,tr|A0A6I8PLB8|A0A6I8PLB8_HUMAN,tr|A0A6I8PIT3|A0A6I8PIT3_HUMAN,tr|A0A6I8PLB3|A0A6I8PLB3_HUMAN,tr|A0A6I8PS05|A0A6I8PS05_HUMAN,tr|B4DER1|B4DER1_HUMAN,tr|A0A6I8PL42|A0A6I8PL42_HUMAN" 9 2301.1845 1.07 86111 17943 3 2301.188292 768.0688 "Leucine--tRNA ligase, cytoplasmic OS=Homo sapiens OX=9606 GN=LARS1 PE=1 SV=2" 6.75 2915.6 - 882688 - - - 1.6652 - 2.749 0.452 - 126.9 1 2 0 0.0038 22 0 0 0 5.40E+07 5.06E+07 - - - 5.9758 1 221125_WJC_METTL3_EV_vs_WT_F06.17944.17944.3 1.55E-11 25/84 R.QPYAVSELAGHQTSAESWGTGR[166.11].A "sp|P36578|RL4_HUMAN,tr|H3BTP7|H3BTP7_HUMAN,tr|H3BU31|H3BU31_HUMAN" 3 2341.0963 1.17 86112 17944 3 2341.103934 781.3727 60S ribosomal protein L4 OS=Homo sapiens OX=9606 GN=RPL4 PE=1 SV=5 5.4 2915.7 - 672075 - - - 3.2792 - 4.301 0.666 - 756.9 1 2 0 0.0077 22 0 0 0 1.57E+08 1.35E+08 - - - 9.4218 0.9979 221125_WJC_METTL3_EV_vs_WT_F06.17945.17945.3 0.0204 Dec-84 R.IEPGVSVSLVNPQPSNGHFSTK.L "sp|Q9P2J5|SYLC_HUMAN,tr|A0A6I8PIV1|A0A6I8PIV1_HUMAN,tr|A0A6I8PRS0|A0A6I8PRS0_HUMAN,tr|A0A6I8PLB8|A0A6I8PLB8_HUMAN,tr|A0A6I8PIT3|A0A6I8PIT3_HUMAN,tr|A0A6I8PLB3|A0A6I8PLB3_HUMAN,tr|A0A6I8PS05|A0A6I8PS05_HUMAN,tr|B4DER1|B4DER1_HUMAN,tr|A0A6I8PL42|A0A6I8PL42_HUMAN" 9 2293.1703 0.9 86113 17945 3 2293.181568 765.3974 "Leucine--tRNA ligase, cytoplasmic OS=Homo sapiens OX=9606 GN=LARS1 PE=1 SV=2" 6.75 2915.9 - 653030 - - - 4.9312 - 2.517 0.378 - 80.8 1 2 0 0.0113 22 0 0 0 5.40E+07 6.00E+07 - - - 4.9396 0.9996 221125_WJC_METTL3_EV_vs_WT_F06.17951.17951.4 0.0107 18/96 K.QVK[136.11]PYVEEGLHPQIIIR[166.11].A "sp|Q99832|TCPH_HUMAN,tr|F8WAM2|F8WAM2_HUMAN" 2 2036.1538 -1 86119 17951 4 2036.160351 510.0457 T-complex protein 1 subunit eta OS=Homo sapiens OX=9606 GN=CCT7 PE=1 SV=2 6.76 2916.6 - 391951 - - - 3.234 - 2.818 0.408 - 210.6 1 2 0 0.0066 17 0 0 0 0.00E+00 0.00E+00 - - - 3.1351 0.9988 221125_WJC_METTL3_EV_vs_WT_F06.17952.17952.4 0.000254 14/96 K.LTIHGDLYYEGKEFETR.L "sp|Q13435|SF3B2_HUMAN,tr|E9PPJ0|E9PPJ0_HUMAN,tr|H0YEX5|H0YEX5_HUMAN" 3 2070.0058 0.06 86120 17952 4 2070.011044 518.5087 Splicing factor 3B subunit 2 OS=Homo sapiens OX=9606 GN=SF3B2 PE=1 SV=2 4.83 2916.8 - 375788 - - - 2.5232 - 2.018 0.408 - 111.3 1 2 1 0.0052 17 0 0 0 2.89E+06 5.25E+07 - - - 3.0196 0.998 221125_WJC_METTL3_EV_vs_WT_F06.17954.17954.3 0.0184 Nov-48 R.QGTTPPIWHLTDK.K "sp|P55265|DSRAD_HUMAN,tr|A0A3B3ITG9|A0A3B3ITG9_HUMAN,tr|A0A3B3IRQ9|A0A3B3IRQ9_HUMAN,tr|A0A3B3ISU1|A0A3B3ISU1_HUMAN,tr|A0A7P0Z4K3|A0A7P0Z4K3_HUMAN,tr|A0A7P0TA14|A0A7P0TA14_HUMAN,tr|A0A3B3ISX1|A0A3B3ISX1_HUMAN,tr|A0A7P0Z4F9|A0A7P0Z4F9_HUMAN" 8 1492.7674 0.72 86122 17954 3 1492.768224 498.5964 Double-stranded RNA-specific adenosine deaminase OS=Homo sapiens OX=9606 GN=ADAR PE=1 SV=4 6.74 2917 - 285886 - - - 0.5332 - 1.774 0.246 - 92.8 1 2 0 0.0008 13 0 0 0 3.29E+06 4.59E+06 - - - 2.8366 0.9998 221125_WJC_METTL3_EV_vs_WT_F06.17959.17959.3 0.0016 13/52 K.SFFDNISC[160.03]DDNR[166.11]ER[166.11].R "sp|Q8ND56|LS14A_HUMAN,tr|A0A096LP11|A0A096LP11_HUMAN,tr|A0A140TA76|A0A140TA76_HUMAN,tr|A0A0G2JQ95|A0A0G2JQ95_HUMAN" 4 1793.7542 0.96 86126 17959 3 1793.757968 598.9253 Protein LSM14 homolog A OS=Homo sapiens OX=9606 GN=LSM14A PE=1 SV=3 4.23 2917.6 - 2.39E+06 - - - 2.1001 - 2.129 0.567 - 157.1 1 2 1 0.0038 14 0 0 0 5.34E+07 5.58E+07 - - - 6.8686 0.9999 221125_WJC_METTL3_EV_vs_WT_F06.17961.17961.3 6.13E-06 Dec-52 K.SFFDNISC[160.03]DDNRER.R "sp|Q8ND56|LS14A_HUMAN,tr|A0A096LP11|A0A096LP11_HUMAN,tr|A0A140TA76|A0A140TA76_HUMAN,tr|A0A0G2JQ95|A0A0G2JQ95_HUMAN" 4 1773.7377 -1 86128 17961 3 1773.74009 592.2532 Protein LSM14 homolog A OS=Homo sapiens OX=9606 GN=LSM14A PE=1 SV=3 4.23 2917.7 - 2.41E+06 - - - 1.3694 - 2.099 0.59 - 154.9 1 2 1 0.0024 14 0 0 0 0.00E+00 0.00E+00 - - - 7.0877 0.9997 221125_WJC_METTL3_EV_vs_WT_F06.17964.17964.3 5.33E-05 Dec-76 K.EK[136.11]EVDGLLTSEPMGSPVSSK[136.11].T "sp|Q8WWM7|ATX2L_HUMAN,tr|H3BUF6|H3BUF6_HUMAN" 2 2105.0533 4.13 86131 17964 3 2105.055447 702.6917 Ataxin-2-like protein OS=Homo sapiens OX=9606 GN=ATXN2L PE=1 SV=2 4.41 2918 - 1.44E+06 - - - 1.0195 - 2.534 0.438 - 139.2 1 2 1 0.0021 20 0 0 0 9.45E+07 2.29E+07 - - - 5.6784 1 221125_WJC_METTL3_EV_vs_WT_F06.17967.17967.4 2.21E-08 18/78 K.HWPFQVINDGDK[136.11]PK[136.11].V "sp|P0DMV8|HS71A_HUMAN,sp|P0DMV9|HS71B_HUMAN,tr|A0A0G2JIW1|A0A0G2JIW1_HUMAN" 3 1695.8704 0.11 86134 17967 4 1695.871533 424.9749 Heat shock 70 kDa protein 1A OS=Homo sapiens OX=9606 GN=HSPA1A PE=1 SV=1 6.75 2918.3 - 633575 - - - 0.674 - 2.697 0.551 - 232.3 1 2 0 0.0011 14 0 0 0 6.96E+06 6.30E+07 - - - 4.3827 0.9997 221125_WJC_METTL3_EV_vs_WT_F06.17968.17968.3 0.000127 9/104 K.LYQGGPGGGSGGGGSGASGGPTIEEVD.- sp|P54652|HSP72_HUMAN 1 2319.0251 - 86135 17968 3 2319.027761 774.0156 Heat shock-related 70 kDa protein 2 OS=Homo sapiens OX=9606 GN=HSPA2 PE=1 SV=1 3.88 2918.4 - 599221 - - - 1.1423 - 2.063 0.365 - 38.4 1 2 0 0.0026 27 0 0 0 - - - - - 4.2747 0.9918 221125_WJC_METTL3_EV_vs_WT_F06.17970.17970.3 2.47E-06 Nov-60 N.AHNDEISGLDLSSQIK.G "sp|Q13610|PWP1_HUMAN,tr|B4DJV5|B4DJV5_HUMAN" 2 1725.8533 3.26 86137 17970 3 1725.855224 576.2917 Periodic tryptophan protein 1 homolog OS=Homo sapiens OX=9606 GN=PWP1 PE=1 SV=1 4.54 2918.6 - 496671 - - - 1.0899 - 2.523 0.418 - 142.5 1 1 0 0.0019 16 0 0 0 6.32E+06 1.94E+06 - - - 5.5743 0.8446 221125_WJC_METTL3_EV_vs_WT_F06.17971.17971.3 0.00287 Dec-60 N.AHNDEISGLDLSSQIK[136.11].G "sp|Q13610|PWP1_HUMAN,tr|B4DJV5|B4DJV5_HUMAN" 2 1733.8675 3.64 86138 17971 3 1733.871378 578.9631 Periodic tryptophan protein 1 homolog OS=Homo sapiens OX=9606 GN=PWP1 PE=1 SV=1 4.54 2918.8 - 429564 - - - 2.2118 - 1.883 0.298 - 141 1 1 0 0.0038 16 0 0 0 7.98E+06 2.19E+06 - - - 3.4852 0.9999 221125_WJC_METTL3_EV_vs_WT_F06.17976.17976.3 4.95E-05 16/64 K.QVK[136.11]PYVEEGLHPQIIIR[166.11].A "sp|Q99832|TCPH_HUMAN,tr|F8WAM2|F8WAM2_HUMAN" 2 2036.1538 0.17 86143 17976 3 2036.161535 679.7252 T-complex protein 1 subunit eta OS=Homo sapiens OX=9606 GN=CCT7 PE=1 SV=2 6.76 2919.4 - 226722 - - - 3.8155 - 3.189 0.514 - 262.5 1 2 0 0.0078 17 0 0 0 9.82E+06 5.94E+07 - - - 7.1982 0.9981 221125_WJC_METTL3_EV_vs_WT_F06.17977.17977.2 0.00151 Jun-32 R.SSIVMGEPISQSSSNSQ.- sp|Q8TCS8|PNPT1_HUMAN 1 1736.7887 - 86144 17977 2 1736.784097 869.4016 "Polyribonucleotide nucleotidyltransferase 1, mitochondrial OS=Homo sapiens OX=9606 GN=PNPT1 PE=1 SV=2" 4 2919.5 - 204632 - - - -2.6468 - 1.418 0.413 - 87.5 1 2 0 -0.0046 17 0 0 0 - - - - - 2.9486 1 221125_WJC_METTL3_EV_vs_WT_F06.17979.17979.3 1.00E-05 20/52 K.HWPFQVINDGDK[136.11]PK[136.11].V "sp|P0DMV8|HS71A_HUMAN,sp|P0DMV9|HS71B_HUMAN,tr|A0A0G2JIW1|A0A0G2JIW1_HUMAN" 3 1695.8704 0.13 86145 17979 3 1695.87359 566.2974 Heat shock 70 kDa protein 1A OS=Homo sapiens OX=9606 GN=HSPA1A PE=1 SV=1 6.75 2919.8 - 2.62E+06 - - - 1.8869 - 3.071 0.555 - 751.3 1 2 0 0.0032 14 0 0 0 7.63E+06 5.75E+07 - - - 7.7086 0.9992 221125_WJC_METTL3_EV_vs_WT_F06.17980.17980.2 1.45E-05 Jul-38 K.EQSQPC[160.03]ADNAVLSSGLTAAR.- "sp|P19784|CSK22_HUMAN,tr|H3BNI9|H3BNI9_HUMAN,tr|H3BSA1|H3BSA1_HUMAN" 3 2073.9749 1.35 86146 17980 2 2073.980869 1037.9947 Casein kinase II subunit alpha' OS=Homo sapiens OX=9606 GN=CSNK2A2 PE=1 SV=1 4.37 2919.9 - 120167 - - - 2.8626 - 1.822 0.501 - 50.8 1 2 0 0.0059 20 0 0 0 2.75E+06 2.04E+06 - - - 4.2145 1 221125_WJC_METTL3_EV_vs_WT_F06.17983.17983.3 0.000114 15/80 K.IWSTVPTDEEDEMEESTNRPR.K sp|Q9GZL7|WDR12_HUMAN 1 2520.1075 1.38 86149 17983 3 2520.104848 841.0431 Ribosome biogenesis protein WDR12 OS=Homo sapiens OX=9606 GN=WDR12 PE=1 SV=2 4 2920.3 - 897715 - - - -1.0373 - 2.286 0.496 - 124.6 1 2 0 -0.0026 21 0 0 0 1.27E+07 9.21E+06 - - - 6.0514 1 221125_WJC_METTL3_EV_vs_WT_F06.17995.17995.2 1.62E-13 17/34 F.DYQQAFGNSTGGFDGQAR.Q sp|Q96PK6|RBM14_HUMAN 1 1917.8242 1.6 86159 17995 2 1917.828423 959.9194 RNA-binding protein 14 OS=Homo sapiens OX=9606 GN=RBM14 PE=1 SV=2 4.21 2921.7 - 261949 - - - 2.2187 - 3.43 0.786 - 871.2 1 1 0 0.0043 18 0 0 0 1.20E+07 7.48E+06 - - - 7.8754 0.9995 221125_WJC_METTL3_EV_vs_WT_F06.17996.17996.4 0.00332 Dec-84 R.YAEIVHLTLPDGTKR.S "sp|P21281|VATB2_HUMAN,tr|H0YC04|H0YC04_HUMAN" 2 1711.9257 1.35 86160 17996 4 1711.926531 428.9887 "V-type proton ATPase subunit B, brain isoform OS=Homo sapiens OX=9606 GN=ATP6V1B2 PE=1 SV=3" 6.75 2921.9 - 197858 - - - 0.4737 - 1.618 0.336 - 61.5 1 2 0 0.0008 15 0 0 0 3.00E+07 2.23E+07 - - - 2.3225 1 221125_WJC_METTL3_EV_vs_WT_F06.18002.18002.3 8.11E-15 23/96 K.LVQDVANNTNEEAGDGTTTATVLAR[166.11].S "sp|P10809|CH60_HUMAN,tr|C9JL25|C9JL25_HUMAN,tr|A0A7I2V2X6|A0A7I2V2X6_HUMAN,tr|A0A7I2YQK6|A0A7I2YQK6_HUMAN,tr|A0A7I2V599|A0A7I2V599_HUMAN,tr|E7EXB4|E7EXB4_HUMAN,tr|A0A7I2YQ71|A0A7I2YQ71_HUMAN,tr|E7ESH4|E7ESH4_HUMAN,tr|A0A7I2V5M1|A0A7I2V5M1_HUMAN,tr|A0A7I2V5K3|A0A7I2V5K3_HUMAN,tr|A0A7I2V369|A0A7I2V369_HUMAN" 11 2569.2495 1.39 86164 18002 3 2569.247567 857.4238 "60 kDa heat shock protein, mitochondrial OS=Homo sapiens OX=9606 GN=HSPD1 PE=1 SV=2" 3.92 2922.6 - 1.71E+06 - - - -0.7613 - 4.039 0.712 - 754.9 1 2 0 -0.002 25 0 0 0 4.15E+07 2.97E+07 - - - 9.6892 1 221125_WJC_METTL3_EV_vs_WT_F06.18005.18005.4 3.40E-07 15/108 R.GLLQDDAHPTLVTYADHSK[136.11].L "sp|Q86U44|MTA70_HUMAN,tr|F5H6D8|F5H6D8_HUMAN,tr|H0YFV6|H0YFV6_HUMAN,tr|B4DTN4|B4DTN4_HUMAN" 4 2088.0367 0.02 86165 18005 4 2088.037078 523.0165 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 5.13 2923 - 6.93E+06 - - - 0.1652 - 2.912 0.581 - 236.1 1 2 0 0.0003 19 0 0 0 3.70E+06 1.50E+08 - - - 4.6445 1 221125_WJC_METTL3_EV_vs_WT_F06.18006.18006.3 3.05E-06 24/72 R.QQAAQAFIHNSLYGPGTNR.T sp|Q9UMY1|NOL7_HUMAN 1 2072.0188 1.07 86166 18006 3 2072.018907 691.6802 Nucleolar protein 7 OS=Homo sapiens OX=9606 GN=NOL7 PE=1 SV=2 8.75 2923.1 - 1.15E+06 - - - 0.0589 - 3.741 0.568 - 889.9 1 2 0 0.0001 19 0 0 0 3.27E+07 3.05E+07 - - - 8.114 0.9982 221125_WJC_METTL3_EV_vs_WT_F06.18011.18011.4 0.222 Oct-96 R.KLNILTRPSGILVNDTK.L sp|Q6NZY4|ZCHC8_HUMAN 1 1881.1047 1.82 86171 18011 4 1881.105603 471.2835 Zinc finger CCHC domain-containing protein 8 OS=Homo sapiens OX=9606 GN=ZCCHC8 PE=1 SV=2 9.99 2923.6 - 217090 - - - 0.4551 - 1.837 0.274 - 92.6 1 2 0 0.0009 17 0 0 0 3.47E+06 1.90E+06 - - - 1.8218 1 221125_WJC_METTL3_EV_vs_WT_F06.18015.18015.3 1.98E-06 14/80 K.IWSTVPTDEEDEMEESTNR[166.11]PR[166.11].K sp|Q9GZL7|WDR12_HUMAN 1 2540.124 1.38 86173 18015 3 2540.124603 847.7153 Ribosome biogenesis protein WDR12 OS=Homo sapiens OX=9606 GN=WDR12 PE=1 SV=2 4 2924.1 - 437775 - - - 0.2366 - 2.18 0.499 - 153 1 2 0 0.0006 21 0 0 0 1.27E+07 9.21E+06 - - - 5.9716 1 221125_WJC_METTL3_EV_vs_WT_F06.18017.18017.3 2.65E-06 21/52 K.HWPFQVINDGDK[136.11]PK[136.11].V "sp|P0DMV8|HS71A_HUMAN,sp|P0DMV9|HS71B_HUMAN,tr|A0A0G2JIW1|A0A0G2JIW1_HUMAN" 3 1695.8704 0.13 86175 18017 3 1695.872621 566.2974 Heat shock 70 kDa protein 1A OS=Homo sapiens OX=9606 GN=HSPA1A PE=1 SV=1 6.75 2924.3 - 1.75E+06 - - - 1.3155 - 3.286 0.555 - 745 1 2 0 0.0022 14 0 0 0 7.63E+06 5.75E+07 - - - 7.8887 0.9996 221125_WJC_METTL3_EV_vs_WT_F06.18018.18018.3 7.28E-06 15/100 R.TPSGDLAITEKDPPGVGVAGVAAAPK.G sp|P42684|ABL2_HUMAN 1 2417.2802 1.98 86176 18018 3 2417.282788 806.7673 Tyrosine-protein kinase ABL2 OS=Homo sapiens OX=9606 GN=ABL2 PE=1 SV=1 4.56 2924.4 - 508933 - - - 1.0686 - 2.036 0.477 - 92.4 1 2 1 0.0026 26 0 0 0 8.38E+06 4.23E+06 - - - 5.4931 0.9998 221125_WJC_METTL3_EV_vs_WT_F06.18025.18025.4 7.23E-08 17/96 R.VQLFEDPTVDK[136.11]EVEIR[166.11]K[136.11].K sp|P51948|MAT1_HUMAN 1 2070.1207 2.17 86181 18025 4 2070.123104 518.5375 CDK-activating kinase assembly factor MAT1 OS=Homo sapiens OX=9606 GN=MNAT1 PE=1 SV=1 4.51 2925.3 - 485419 - - - 1.1415 - 2.982 0.484 - 174.6 1 2 1 0.0024 17 0 0 0 1.17E+07 5.39E+06 - - - 3.8174 1 221125_WJC_METTL3_EV_vs_WT_F06.18027.18027.2 3.48E-12 14/34 F.DYQQAFGNSTGGFDGQAR[166.11].Q sp|Q96PK6|RBM14_HUMAN 1 1927.8324 1.6 86182 18027 2 1927.831709 964.9235 RNA-binding protein 14 OS=Homo sapiens OX=9606 GN=RBM14 PE=1 SV=2 4.21 2925.7 - 355709 - - - -0.3781 - 2.756 0.71 - 585.6 1 1 0 -0.0007 18 0 0 0 1.20E+07 7.48E+06 - - - 6.7773 0.9998 221125_WJC_METTL3_EV_vs_WT_F06.18031.18031.4 3.23E-06 16/96 K.QVKPYVEEGLHPQIIIR.A "sp|Q99832|TCPH_HUMAN,tr|F8WAM2|F8WAM2_HUMAN" 2 2018.1313 0.16 86185 18031 4 2018.134827 505.5401 T-complex protein 1 subunit eta OS=Homo sapiens OX=9606 GN=CCT7 PE=1 SV=2 6.76 2926 - 2.58E+06 - - - 1.7496 - 2.654 0.407 - 164.1 1 2 0 0.0035 17 0 0 0 3.12E+07 1.95E+08 - - - 3.1064 1 221125_WJC_METTL3_EV_vs_WT_F06.18034.18034.3 5.29E-09 15/56 K.QISNLQQSISDAEQR.G sp|P04264|K2C1_HUMAN 1 1715.8438 9.64 86187 18034 3 1715.846293 572.9552 "Keratin, type II cytoskeletal 1 OS=Homo sapiens OX=9606 GN=KRT1 PE=1 SV=6" 4.37 2926.4 - 1.16E+06 - - - 1.429 - 2.851 0.521 - 331 1 2 0 0.0025 15 0 0 0 6.50E+07 6.75E+06 - - - 7.0817 1 221125_WJC_METTL3_EV_vs_WT_F06.18038.18038.3 5.37E-06 13/72 R.GLLQDDAHPTLVTYADHSK[136.11].L "sp|Q86U44|MTA70_HUMAN,tr|F5H6D8|F5H6D8_HUMAN,tr|H0YFV6|H0YFV6_HUMAN,tr|B4DTN4|B4DTN4_HUMAN" 4 2088.0367 0.37 86190 18038 3 2088.036788 697.0195 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 5.13 2926.8 - 2.86E+06 - - - 0.0263 - 2.539 0.552 - 194.3 1 2 0 0.0001 19 0 0 0 3.45E+07 9.33E+07 - - - 6.9834 0.9999 221125_WJC_METTL3_EV_vs_WT_F06.18047.18047.2 0.000133 18-Oct K.NMQDMVEDYR.N sp|P04264|K2C1_HUMAN 1 1299.5224 18.77 86197 18047 2 1299.521216 650.7685 "Keratin, type II cytoskeletal 1 OS=Homo sapiens OX=9606 GN=KRT1 PE=1 SV=6" 4.03 2927.9 - 631089 - - - -0.8896 - 2.183 0.537 - 384.9 1 2 0 -0.0012 10 0 0 0 1.04E+07 5.54E+05 - - - 5.1861 0.9997 221125_WJC_METTL3_EV_vs_WT_F06.18049.18049.3 0.000479 14/48 K.DTDSEEEIR[166.11]EAFR[166.11].V "sp|P0DP25|CALM3_HUMAN,sp|P0DP23|CALM1_HUMAN,sp|P0DP24|CALM2_HUMAN,tr|G3V361|G3V361_HUMAN,tr|A0A590UJI2|A0A590UJI2_HUMAN,tr|Q96HY3|Q96HY3_HUMAN,tr|A0A590UJC0|A0A590UJC0_HUMAN,tr|G3V226|G3V226_HUMAN,tr|E7EMB3|E7EMB3_HUMAN" 9 1615.7229 1.31 86199 18049 3 1615.725542 539.5816 Calmodulin-3 OS=Homo sapiens OX=9606 GN=CALM3 PE=1 SV=1 4.08 2928.1 - 902463 - - - 1.6451 - 2.574 0.447 - 353.9 1 2 1 0.0027 13 0 0 0 3.13E+07 2.39E+07 - - - 6.0863 0.9998 221125_WJC_METTL3_EV_vs_WT_F06.18052.18052.4 7.35E-05 14/90 R.K[136.11]LLSSDR[166.11]NPPIDDLIK[136.11].S "sp|O00505|IMA4_HUMAN,sp|O00629|IMA3_HUMAN,tr|A0A7I2YQ95|A0A7I2YQ95_HUMAN,tr|H7C4F6|H7C4F6_HUMAN,tr|A0A7I2V340|A0A7I2V340_HUMAN,tr|A0A7I2V333|A0A7I2V333_HUMAN" 6 1849.0519 0.92 86202 18052 4 1849.052757 463.2703 Importin subunit alpha-4 OS=Homo sapiens OX=9606 GN=KPNA3 PE=1 SV=2 6.04 2928.4 - 486758 - - - 0.4456 - 2.388 0.475 - 123.7 1 2 1 0.0008 16 0 0 0 9.71E+06 1.05E+07 - - - 3.6668 0.9999 221125_WJC_METTL3_EV_vs_WT_F06.18055.18055.3 8.64E-05 Aug-76 R.FSSC[160.03]GGGGGSFGAGGGFGSR.S sp|P04264|K2C1_HUMAN 1 1764.7274 0.1 86205 18055 3 1764.728871 589.2498 "Keratin, type II cytoskeletal 1 OS=Homo sapiens OX=9606 GN=KRT1 PE=1 SV=6" 8.25 2928.8 - 326937 - - - 0.816 - 1.775 0.467 - 45.7 1 2 0 0.0014 20 0 0 0 7.55E+06 7.33E+07 - - - 5.1382 1 221125_WJC_METTL3_EV_vs_WT_F06.18056.18056.2 3.59E-08 13/32 K.SQIFSTASDNQPTVTIK[136.11].V "sp|P11021|BIP_HUMAN,tr|A0A7P0TB36|A0A7P0TB36_HUMAN,tr|A0A7P0TAI0|A0A7P0TAI0_HUMAN" 3 1843.9407 0.44 86206 18056 2 1843.937884 922.9776 Endoplasmic reticulum chaperone BiP OS=Homo sapiens OX=9606 GN=HSPA5 PE=1 SV=2 5.55 2929 - 149529 - - - -1.5315 - 2.805 0.627 - 298.3 1 2 0 -0.0028 17 0 0 0 5.15E+06 1.17E+07 - - - 6.2069 0.9969 221125_WJC_METTL3_EV_vs_WT_F06.18065.18065.4 0.0165 16/90 R.KLLSSDRNPPIDDLIK.S "sp|O00505|IMA4_HUMAN,sp|O00629|IMA3_HUMAN,tr|A0A7I2YQ95|A0A7I2YQ95_HUMAN,tr|H7C4F6|H7C4F6_HUMAN,tr|A0A7I2V340|A0A7I2V340_HUMAN,tr|A0A7I2V333|A0A7I2V333_HUMAN" 6 1823.0153 0.92 86213 18065 4 1823.02018 456.7611 Importin subunit alpha-4 OS=Homo sapiens OX=9606 GN=KPNA3 PE=1 SV=2 6.04 2929.9 - 577431 - - - 2.6972 - 2.337 0.351 - 150.4 1 2 1 0.0049 16 0 0 0 9.71E+06 1.05E+07 - - - 2.5788 0.9898 221125_WJC_METTL3_EV_vs_WT_F06.18066.18066.3 0.000139 15/48 N.KLNDLEDALQQAK.E sp|P04264|K2C1_HUMAN 1 1484.7835 29.33 86214 18066 3 1484.788017 495.9351 "Keratin, type II cytoskeletal 1 OS=Homo sapiens OX=9606 GN=KRT1 PE=1 SV=6" 4.56 2930.1 - 498604 - - - 3.0611 - 3.202 0.456 - 461.5 1 1 0 0.0045 13 0 0 0 6.75E+06 2.30E+05 - - - 6.778 0.9997 221125_WJC_METTL3_EV_vs_WT_F06.18068.18068.3 1.01E-11 19/76 K.FLGSDEEDK[136.11]DSLQELSTEQK[136.11].C "sp|Q99567|NUP88_HUMAN,tr|J3KMX1|J3KMX1_HUMAN" 2 2313.0831 1.67 86216 18068 3 2313.08959 772.035 Nuclear pore complex protein Nup88 OS=Homo sapiens OX=9606 GN=NUP88 PE=1 SV=2 3.95 2930.3 - 461257 - - - 2.814 - 3.269 0.519 - 247.4 1 2 1 0.0065 20 0 0 0 7.39E+07 4.42E+07 - - - 7.1981 1 221125_WJC_METTL3_EV_vs_WT_F06.18072.18072.3 9.14E-12 26/64 K.EVVHTVSLHEIDVINSR[166.11].T "sp|Q9Y230|RUVB2_HUMAN,tr|M0R0Y3|M0R0Y3_HUMAN" 2 1956.0304 1 86219 18072 3 1956.031446 653.0174 RuvB-like 2 OS=Homo sapiens OX=9606 GN=RUVBL2 PE=1 SV=3 5.28 2930.9 - 1.75E+06 - - - 0.5296 - 4.429 0.633 - 1285.3 1 2 0 0.001 17 0 0 0 2.57E+07 2.58E+07 - - - 9.3566 1 221125_WJC_METTL3_EV_vs_WT_F06.18074.18074.3 1.56E-09 21/76 K.FLGSDEEDKDSLQELSTEQK.C "sp|Q99567|NUP88_HUMAN,tr|J3KMX1|J3KMX1_HUMAN" 2 2297.0547 1.67 86221 18074 3 2297.055486 766.6922 Nuclear pore complex protein Nup88 OS=Homo sapiens OX=9606 GN=NUP88 PE=1 SV=2 3.95 2931 - 1.44E+06 - - - 0.3504 - 3.289 0.649 - 324.2 1 2 1 0.0008 20 0 0 0 7.38E+07 4.42E+07 - - - 8.6639 0.9995 221125_WJC_METTL3_EV_vs_WT_F06.18076.18076.4 0.00546 Dec-84 R.YAEIVHLTLPDGTK[136.11]R[166.11].S "sp|P21281|VATB2_HUMAN,tr|H0YC04|H0YC04_HUMAN" 2 1729.9482 1.25 86223 18076 4 1729.947535 433.4943 "V-type proton ATPase subunit B, brain isoform OS=Homo sapiens OX=9606 GN=ATP6V1B2 PE=1 SV=3" 6.75 2931.3 - 665929 - - - -0.3786 - 2.26 0.331 - 76.5 1 2 0 -0.0007 15 0 0 0 1.75E+07 1.40E+07 - - - 2.3986 0.8419 221125_WJC_METTL3_EV_vs_WT_F06.18077.18077.4 0.00067 Nov-72 T.DK[136.11]PLR[166.11]LPLQDVYK[136.11].L "sp|Q05639|EF1A2_HUMAN,sp|P68104|EF1A1_HUMAN,sp|Q5VTE0|EF1A3_HUMAN,tr|A0A7I2V659|A0A7I2V659_HUMAN,tr|A0A7I2V3H3|A0A7I2V3H3_HUMAN,tr|A0A2U3TZH3|A0A2U3TZH3_HUMAN,tr|A0A7I2V5N4|A0A7I2V5N4_HUMAN,tr|A0A087WVQ9|A0A087WVQ9_HUMAN,tr|A0A087WV01|A0A087WV01_HUMAN" 9 1609.9402 0.81 86224 18077 4 1609.942463 403.4923 Elongation factor 1-alpha 2 OS=Homo sapiens OX=9606 GN=EEF1A2 PE=1 SV=1 8.5 2931.4 - 448613 - - - 1.4069 - 1.944 0.35 - 104.6 1 1 1 0.0023 13 0 0 0 5.81E+06 7.19E+06 - - - 2.5182 0.9839 221125_WJC_METTL3_EV_vs_WT_F06.18080.18080.4 0.0493 15/96 K.EVVHTVSLHEIDVINSR[166.11].T "sp|Q9Y230|RUVB2_HUMAN,tr|M0R0Y3|M0R0Y3_HUMAN" 2 1956.0304 0.98 86225 18080 4 1956.032167 490.0149 RuvB-like 2 OS=Homo sapiens OX=9606 GN=RUVBL2 PE=1 SV=3 5.28 2931.8 - 6.69E+06 - - - 0.8982 - 2.293 0.171 - 112.5 1 2 0 0.0018 17 0 0 0 4.66E+07 4.75E+07 - - - 1.002 0.8668 221125_WJC_METTL3_EV_vs_WT_F06.18081.18081.4 0.0569 13/96 K.EVVHTVSLHEIDVINSR.T "sp|Q9Y230|RUVB2_HUMAN,tr|M0R0Y3|M0R0Y3_HUMAN" 2 1946.0221 0.98 86226 18081 4 1946.024729 487.5128 RuvB-like 2 OS=Homo sapiens OX=9606 GN=RUVBL2 PE=1 SV=3 5.28 2931.8 - 4.83E+06 - - - 1.3304 - 2.183 0.093 - 98.4 1 2 0 0.0026 17 0 0 0 4.66E+07 4.76E+07 - - - 0.3058 1 221125_WJC_METTL3_EV_vs_WT_F06.18083.18083.3 1.67E-10 23/64 K.EVVHTVSLHEIDVINSR.T "sp|Q9Y230|RUVB2_HUMAN,tr|M0R0Y3|M0R0Y3_HUMAN" 2 1946.0221 0.93 86228 18083 3 1946.027506 649.6813 RuvB-like 2 OS=Homo sapiens OX=9606 GN=RUVBL2 PE=1 SV=3 5.28 2932 - 2.08E+06 - - - 2.7574 - 3.929 0.641 - 950.3 1 2 0 0.0054 17 0 0 0 2.39E+07 2.58E+07 - - - 9.142 1 221125_WJC_METTL3_EV_vs_WT_F06.18084.18084.3 2.59E-16 22/88 K.VKGTAGLSQNSTLEVQTLSVAPK.A "sp|Q96QA5|GSDMA_HUMAN,tr|J3KRG2|J3KRG2_HUMAN" 2 2327.2696 999 86229 18084 3 2327.274105 776.7638 Gasdermin-A OS=Homo sapiens OX=9606 GN=GSDMA PE=1 SV=4 8.56 2932.1 - 1.78E+06 - - - 1.9186 - 4.192 0.701 - 568.2 1 2 1 0.0045 23 0 0 0 3.26E+07 0.00E+00 - - - 9.7164 1 221125_WJC_METTL3_EV_vs_WT_F06.18085.18085.3 1.04E-10 23/68 R.IRNELMQSLNQDSNSNFK.D "sp|Q15643|TRIPB_HUMAN,tr|H0YJ97|H0YJ97_HUMAN" 2 2137.0222 0.73 86230 18085 3 2137.025566 713.348 Thyroid receptor-interacting protein 11 OS=Homo sapiens OX=9606 GN=TRIP11 PE=1 SV=3 6.07 2932.2 - 1.77E+06 - - - 1.5676 - 3.865 0.632 - 596.3 1 2 1 0.0034 18 0 0 0 1.39E+07 1.89E+07 - - - 8.9518 0.9999 221125_WJC_METTL3_EV_vs_WT_F06.18086.18086.4 0.000313 18/102 K.IQPVEVDK[136.11]YGNIDAVHLK[136.11].A "sp|P23378|GCSP_HUMAN,tr|A0A1W2PQV3|A0A1W2PQV3_HUMAN,tr|A0A1W2PQU6|A0A1W2PQU6_HUMAN,tr|A0A1W2PP74|A0A1W2PP74_HUMAN" 4 2053.1179 0.22 86231 18086 4 2053.120021 514.2867 "Glycine dehydrogenase (decarboxylating), mitochondrial OS=Homo sapiens OX=9606 GN=GLDC PE=1 SV=2" 5.38 2932.3 - 1.29E+06 - - - 1.0374 - 3.267 0.572 - 214.9 1 2 1 0.0021 18 0 0 0 2.10E+06 9.57E+06 - - - 4.6096 0.9637 221125_WJC_METTL3_EV_vs_WT_F06.18088.18088.4 0.0121 16/120 R.ALEKEPVPSALPPSLIPPSKR.K "sp|Q9UBC2|EP15R_HUMAN,tr|M0R2S2|M0R2S2_HUMAN,tr|M0R165|M0R165_HUMAN" 3 2225.2784 2.61 86233 18088 4 2225.283674 557.3269 Epidermal growth factor receptor substrate 15-like 1 OS=Homo sapiens OX=9606 GN=EPS15L1 PE=1 SV=1 8.63 2932.5 - 527670 - - - 2.3907 - 2.605 0.219 - 146.2 1 2 1 0.0053 21 0 0 0 4.95E+06 1.89E+06 - - - 1.4473 0.9997 221125_WJC_METTL3_EV_vs_WT_F06.18089.18089.4 0.00633 Sep-66 K.STLHNWMSEFKR.W sp|O60264|SMCA5_HUMAN 1 1534.7351 0.5 86234 18089 4 1534.736921 384.691 SWI\SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A member 5 OS=Homo sapiens OX=9606 GN=SMARCA5 PE=1 SV=1 8.49 2932.7 - 326173 - - - 1.1983 - 1.702 0.371 - 50.4 1 2 0 0.0018 12 0 0 0 1.79E+06 3.58E+06 - - - 2.6559 1 221125_WJC_METTL3_EV_vs_WT_F06.18097.18097.3 3.64E-08 13/64 K.SQIFSTASDNQPTVTIK[136.11].V "sp|P11021|BIP_HUMAN,tr|A0A7P0TB36|A0A7P0TB36_HUMAN,tr|A0A7P0TAI0|A0A7P0TAI0_HUMAN" 3 1843.9407 1.11 86241 18097 3 1843.943983 615.6542 Endoplasmic reticulum chaperone BiP OS=Homo sapiens OX=9606 GN=HSPA5 PE=1 SV=2 5.55 2933.5 - 1.22E+06 - - - 1.7761 - 2.433 0.555 - 171.9 1 2 0 0.0033 17 0 0 0 1.45E+07 1.31E+07 - - - 6.973 1 221125_WJC_METTL3_EV_vs_WT_F06.18099.18099.3 1.90E-09 21/72 K.K[136.11]AEAAASALADADADLEER[166.11].L "sp|O43633|CHM2A_HUMAN,tr|M0R1T5|M0R1T5_HUMAN" 2 1933.9348 1.46 86243 18099 3 1934.934661 645.6522 Charged multivesicular body protein 2a OS=Homo sapiens OX=9606 GN=CHMP2A PE=1 SV=1 4.02 2933.7 - 1.09E+06 - - - 517.0169 - 4.037 0.615 - 740.6 1 2 0 0.9999 19 0 0 0 1.46E+07 1.00E+07 - - - 8.5481 1 221125_WJC_METTL3_EV_vs_WT_F06.18101.18101.4 3.91E-05 15/84 R.NAHSTAIAGLTFLHR[166.11].E "sp|Q8NI36|WDR36_HUMAN,tr|A0A0A0MTB8|A0A0A0MTB8_HUMAN" 2 1617.8615 1.06 86245 18101 4 1617.863013 405.4726 WD repeat-containing protein 36 OS=Homo sapiens OX=9606 GN=WDR36 PE=1 SV=1 9.76 2934 - 529640 - - - 0.9389 - 3.043 0.481 - 243.8 1 2 0 0.0015 15 0 0 0 8.65E+06 8.13E+06 - - - 3.8104 1 221125_WJC_METTL3_EV_vs_WT_F06.18102.18102.2 1.63E-06 16/28 K.QISNLQQSISDAEQR.G sp|P04264|K2C1_HUMAN 1 1715.8438 332.86 86246 18102 2 1715.84531 858.9292 "Keratin, type II cytoskeletal 1 OS=Homo sapiens OX=9606 GN=KRT1 PE=1 SV=6" 4.37 2934.1 - 714197 - - - 0.8561 - 3.344 0.568 - 564 1 2 0 0.0015 15 0 0 0 4.25E+07 1.28E+05 - - - 6.2037 0.9991 221125_WJC_METTL3_EV_vs_WT_F06.18104.18104.4 0.000305 Oct-78 R.VDK[136.11]ITEYLC[160.03]EPLR[166.11]K[136.11].C "sp|P63010|AP2B1_HUMAN,sp|Q10567|AP1B1_HUMAN,tr|K7ERB2|K7ERB2_HUMAN,tr|A0A087WZQ6|A0A087WZQ6_HUMAN,tr|K7EN71|K7EN71_HUMAN,tr|C9J1E7|C9J1E7_HUMAN,tr|A0A087WU93|A0A087WU93_HUMAN" 7 1788.9654 0.7 86248 18104 4 1788.966383 448.2486 AP-2 complex subunit beta OS=Homo sapiens OX=9606 GN=AP2B1 PE=1 SV=1 6.15 2934.4 - 387138 - - - 0.5344 - 2.028 0.372 - 76.9 1 2 1 0.001 14 0 0 0 1.69E+06 2.40E+06 - - - 2.7209 0.983 221125_WJC_METTL3_EV_vs_WT_F06.18105.18105.4 0.0291 Oct-78 R.VDKITEYLC[160.03]EPLRK.C "sp|P63010|AP2B1_HUMAN,sp|Q10567|AP1B1_HUMAN,tr|K7ERB2|K7ERB2_HUMAN,tr|A0A087WZQ6|A0A087WZQ6_HUMAN,tr|K7EN71|K7EN71_HUMAN,tr|C9J1E7|C9J1E7_HUMAN,tr|A0A087WU93|A0A087WU93_HUMAN" 7 1762.9288 0.7 86249 18105 4 1762.928616 441.7395 AP-2 complex subunit beta OS=Homo sapiens OX=9606 GN=AP2B1 PE=1 SV=1 6.15 2934.5 - 352316 - - - -0.08 - 1.733 0.235 - 66.2 1 2 1 -0.0001 14 0 0 0 1.69E+06 2.40E+06 - - - 1.4715 0.9835 221125_WJC_METTL3_EV_vs_WT_F06.18106.18106.4 0.15 Oct-66 K.STLHNWMSEFK[136.11]R[166.11].W sp|O60264|SMCA5_HUMAN 1 1552.7576 0.53 86250 18106 4 1552.757438 389.1967 SWI\SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A member 5 OS=Homo sapiens OX=9606 GN=SMARCA5 PE=1 SV=1 8.49 2934.6 - 241384 - - - -0.0734 - 1.551 0.184 - 68.5 1 2 0 -0.0001 12 0 0 0 1.79E+06 3.39E+06 - - - 0.9936 1 221125_WJC_METTL3_EV_vs_WT_F06.18107.18107.2 2.99E-11 Nov-40 R.KGPQNQVGAGTTTGLFGSSPA.T "sp|P52948|NUP98_HUMAN,tr|A0A3B3ITD8|A0A3B3ITD8_HUMAN" 2 1973.9807 6.36 86251 18107 2 1973.982653 987.9976 Nuclear pore complex protein Nup98-Nup96 OS=Homo sapiens OX=9606 GN=NUP98 PE=1 SV=4 8.75 2934.7 - 222941 - - - 1.0051 - 3.058 0.564 - 111.5 1 1 0 0.002 21 0 0 0 1.69E+06 2.65E+05 - - - 5.9541 1 221125_WJC_METTL3_EV_vs_WT_F06.18113.18113.3 3.40E-07 13/52 R.SSHSTWPVDVSQIK[136.11].Q sp|Q6P2E9|EDC4_HUMAN 1 1577.7929 2.48 86255 18113 3 1577.794008 526.9383 Enhancer of mRNA-decapping protein 4 OS=Homo sapiens OX=9606 GN=EDC4 PE=1 SV=1 6.46 2935.4 - 1.35E+06 - - - 0.6889 - 2.89 0.539 - 231.1 1 2 0 0.0011 14 0 0 0 6.52E+07 2.63E+07 - - - 7.3693 0.9998 221125_WJC_METTL3_EV_vs_WT_F06.18115.18115.4 6.54E-07 20/90 R.DLK[136.11]PQNLLIDDK[136.11]GTIK[136.11].L "sp|P06493|CDK1_HUMAN,tr|E5RIU6|E5RIU6_HUMAN,tr|A0A024QZP7|A0A024QZP7_HUMAN,tr|A0A087WZZ9|A0A087WZZ9_HUMAN" 4 1834.0626 1.32 86257 18115 4 1834.064165 459.5229 Cyclin-dependent kinase 1 OS=Homo sapiens OX=9606 GN=CDK1 PE=1 SV=3 6.04 2935.7 - 914431 - - - 0.8457 - 2.599 0.48 - 247.7 1 2 1 0.0016 16 0 0 0 1.57E+07 1.19E+07 - - - 3.7399 1 221125_WJC_METTL3_EV_vs_WT_F06.18116.18116.4 1.53E-07 18/84 R.NAHSTAIAGLTFLHR.E "sp|Q8NI36|WDR36_HUMAN,tr|A0A0A0MTB8|A0A0A0MTB8_HUMAN" 2 1607.8532 1.07 86258 18116 4 1607.854404 402.9706 WD repeat-containing protein 36 OS=Homo sapiens OX=9606 GN=WDR36 PE=1 SV=1 9.76 2935.8 - 724555 - - - 0.7339 - 2.865 0.47 - 391.5 1 2 0 0.0012 15 0 0 0 8.69E+06 8.13E+06 - - - 3.6932 0.9459 221125_WJC_METTL3_EV_vs_WT_F06.18117.18117.3 0.00441 13/80 R.KGPQNQVGAGTTTGLFGSSPA.T "sp|P52948|NUP98_HUMAN,tr|A0A3B3ITD8|A0A3B3ITD8_HUMAN" 2 1973.9807 3.82 86259 18117 3 1973.986361 659.0008 Nuclear pore complex protein Nup98-Nup96 OS=Homo sapiens OX=9606 GN=NUP98 PE=1 SV=4 8.75 2935.9 - 611383 - - - 2.8835 - 2.659 0.351 - 76.3 1 1 0 0.0057 21 0 0 0 2.99E+06 7.83E+05 - - - 4.7963 1 221125_WJC_METTL3_EV_vs_WT_F06.18119.18119.2 8.01E-09 14/32 K.SQIFSTASDNQPTVTIK.V "sp|P11021|BIP_HUMAN,tr|A0A7P0TB36|A0A7P0TB36_HUMAN,tr|A0A7P0TAI0|A0A7P0TAI0_HUMAN" 3 1835.9265 0.44 86261 18119 2 1835.92689 918.9705 Endoplasmic reticulum chaperone BiP OS=Homo sapiens OX=9606 GN=HSPA5 PE=1 SV=2 5.55 2936.2 - 495218 - - - 0.2081 - 2.56 0.598 - 191 1 2 0 0.0004 17 0 0 0 5.15E+06 1.17E+07 - - - 5.7688 0.9979 221125_WJC_METTL3_EV_vs_WT_F06.18120.18120.3 0.0121 14/56 R.DLEIERPILGQNDNK.S "sp|Q9UGV2|NDRG3_HUMAN,tr|Q5TH30|Q5TH30_HUMAN,tr|F8WBF9|F8WBF9_HUMAN" 3 1752.9006 0.66 86262 18120 3 1752.908332 585.3075 Protein NDRG3 OS=Homo sapiens OX=9606 GN=NDRG3 PE=1 SV=2 4.32 2936.3 - 425683 - - - 4.3956 - 2.121 0.366 - 144.7 1 2 0 0.0077 15 0 0 0 6.12E+06 9.23E+06 - - - 4.5804 0.9878 221125_WJC_METTL3_EV_vs_WT_F06.18121.18121.3 0.549 Jul-52 K.SPTDDEVTPSAVVR[166.11].R "sp|Q9Y2H5|PKHA6_HUMAN,tr|A0A1B0GUN5|A0A1B0GUN5_HUMAN,tr|Q5VTI5|Q5VTI5_HUMAN" 3 1481.7237 0.001 86263 18121 3 1481.724208 494.9152 Pleckstrin homology domain-containing family A member 6 OS=Homo sapiens OX=9606 GN=PLEKHA6 PE=1 SV=4 4.03 2936.5 - 384679 - - - 0.328 - 1.577 0.206 - 41.3 6 2 0 0.0005 14 0 0 0 0.00E+00 2.76E+06 - - - 1.687 1 221125_WJC_METTL3_EV_vs_WT_F06.18126.18126.3 3.19E-09 29/88 R.GNFGGSFAGSFGGAGGHAPGVAR[166.11].K "sp|P52272|HNRPM_HUMAN,tr|M0R2I7|M0R2I7_HUMAN,tr|M0QY96|M0QY96_HUMAN,tr|A0A087X0X3|A0A087X0X3_HUMAN" 4 2043.9539 1.76 86267 18126 3 2043.956763 682.3252 Heterogeneous nuclear ribonucleoprotein M OS=Homo sapiens OX=9606 GN=HNRNPM PE=1 SV=3 9.76 2936.9 - 4.01E+06 - - - 1.4056 - 4.708 0.694 - 973.9 1 2 0 0.0029 23 0 0 0 3.75E+09 2.12E+09 - - - 9.9111 0.9859 221125_WJC_METTL3_EV_vs_WT_F06.18129.18129.4 0.00163 14/90 R.ALK[136.11]DEEK[136.11]MELQEIQLK[136.11].E "sp|P06753|TPM3_HUMAN,tr|A0A2R2Y2Q3|A0A2R2Y2Q3_HUMAN,tr|A0A087WWU8|A0A087WWU8_HUMAN,tr|J3KN67|J3KN67_HUMAN,tr|A0A494C0P6|A0A494C0P6_HUMAN" 5 1968.0664 2.05 86270 18129 4 1968.068075 493.0239 Tropomyosin alpha-3 chain OS=Homo sapiens OX=9606 GN=TPM3 PE=1 SV=2 4.59 2937.2 - 687433 - - - 0.8618 - 2.509 0.229 - 133.8 1 2 2 0.0017 16 0 0 0 5.36E+07 2.62E+07 - - - 1.5428 0.9997 221125_WJC_METTL3_EV_vs_WT_F06.18133.18133.4 6.27E-05 16/66 K.RELDELKPWIEK.T sp|O43395|PRPF3_HUMAN 1 1554.8406 0.83 86274 18133 4 1554.840845 389.7174 U4\U6 small nuclear ribonucleoprotein Prp3 OS=Homo sapiens OX=9606 GN=PRPF3 PE=1 SV=2 4.87 2937.7 - 546164 - - - 0.1621 - 2.433 0.345 - 235 1 2 0 0.0003 12 0 0 0 8.54E+06 1.03E+07 - - - 2.5653 1 221125_WJC_METTL3_EV_vs_WT_F06.18140.18140.3 3.42E-10 21/96 Q.GSSLASYGNQPSSYGAQAASSYGVR.A sp|Q96PK6|RBM14_HUMAN 1 2464.1255 2.45 86279 18140 3 2464.126346 822.3824 RNA-binding protein 14 OS=Homo sapiens OX=9606 GN=RBM14 PE=1 SV=2 8.5 2938.5 - 1.19E+06 - - - 0.3454 - 3.775 0.625 - 308.7 1 1 0 0.0009 25 0 0 0 9.65E+06 3.93E+06 - - - 8.5641 0.9999 221125_WJC_METTL3_EV_vs_WT_F06.18142.18142.4 2.26E-06 17/90 K.IVIDSEIKDSLLSNKK.A sp|Q8IWI9|MGAP_HUMAN 1 1801.0197 1.84 86281 18142 4 1801.020533 451.2622 MAX gene-associated protein OS=Homo sapiens OX=9606 GN=MGA PE=1 SV=4 6.12 2938.7 - 956460 - - - 0.4736 - 2.672 0.538 - 186.5 1 2 1 0.0009 16 0 0 0 6.42E+06 3.48E+06 - - - 4.2547 1 221125_WJC_METTL3_EV_vs_WT_F06.18143.18143.3 1.36E-06 21/76 R.EQIVVDLSHPGVSEDDQVSR.L sp|O60701|UGDH_HUMAN 1 2208.0659 2.94 86282 18143 3 2208.067233 737.0292 UDP-glucose 6-dehydrogenase OS=Homo sapiens OX=9606 GN=UGDH PE=1 SV=1 4.1 2938.9 - 899486 - - - 0.6241 - 3.957 0.629 - 418.8 1 2 0 0.0014 20 0 0 0 1.82E+07 6.20E+06 - - - 8.8893 0.9909 221125_WJC_METTL3_EV_vs_WT_F06.18147.18147.4 6.20E-05 14/90 K.IVIDSEIK[136.11]DSLLSNK[136.11]K[136.11].A sp|Q8IWI9|MGAP_HUMAN 1 1825.0623 1.84 86286 18147 4 1825.068178 457.2728 MAX gene-associated protein OS=Homo sapiens OX=9606 GN=MGA PE=1 SV=4 6.12 2939.3 - 513300 - - - 3.2317 - 2.403 0.313 - 128.4 1 2 1 0.0059 16 0 0 0 6.42E+06 3.48E+06 - - - 2.2575 1 221125_WJC_METTL3_EV_vs_WT_F06.18149.18149.2 3.40E-13 18/42 R.VSSPLPSPSAMTDAANSQAAAK.L "sp|Q8WXI9|P66B_HUMAN,tr|A0A0U1RRM1|A0A0U1RRM1_HUMAN,tr|A0A0U1RR30|A0A0U1RR30_HUMAN" 3 2100.0157 2.19 86288 18149 2 2100.017041 1051.0151 Transcriptional repressor p66-beta OS=Homo sapiens OX=9606 GN=GATAD2B PE=1 SV=1 5.81 2939.6 - 489060 - - - 0.6224 - 3.658 0.582 - 780.3 1 2 0 0.0013 22 0 0 0 6.98E+07 3.19E+07 - - - 6.5278 1 221125_WJC_METTL3_EV_vs_WT_F06.18150.18150.4 3.78E-06 15/96 R.FDSYPMVLGAQHFHSGK.H "sp|P19474|RO52_HUMAN,tr|H0YDP8|H0YDP8_HUMAN" 2 1919.8989 1.75 86289 18150 4 1919.898656 480.982 E3 ubiquitin-protein ligase TRIM21 OS=Homo sapiens OX=9606 GN=TRIM21 PE=1 SV=1 6.92 2939.7 - 449284 - - - -0.1026 - 2.78 0.47 - 169.8 1 2 0 -0.0002 17 0 0 0 1.41E+07 8.02E+06 - - - 3.6718 0.9907 221125_WJC_METTL3_EV_vs_WT_F06.18151.18151.4 0.0169 Dec-90 R.DDK[136.11]ER[166.11]PPFIPEGVVAR[166.11].R sp|Q9BZE4|GTPB4_HUMAN 1 1851.9837 1.08 86290 18151 4 1851.986846 464.0032 GTP-binding protein 4 OS=Homo sapiens OX=9606 GN=GTPBP4 PE=1 SV=3 4.78 2939.8 - 198864 - - - 1.6787 - 1.872 0.271 - 88.7 1 2 1 0.0031 16 0 0 0 4.17E+06 3.85E+06 - - - 1.8048 1 221125_WJC_METTL3_EV_vs_WT_F06.18157.18157.3 4.35E-10 21/68 R.RSLGYAYVNFQQPADAER.A "sp|Q13310|PABP4_HUMAN,sp|P11940|PABP1_HUMAN,tr|A0A7I2V649|A0A7I2V649_HUMAN,tr|B1ANR0|B1ANR0_HUMAN,tr|A0A7I2V4L7|A0A7I2V4L7_HUMAN,tr|E5RHG7|E5RHG7_HUMAN,tr|B1ANR1|B1ANR1_HUMAN,tr|H0YAR2|H0YAR2_HUMAN,tr|E7ERJ7|E7ERJ7_HUMAN,tr|E5RJB9|E5RJB9_HUMAN,tr|A0A7I2YQ88|A0A7I2YQ88_HUMAN,tr|E5RH24|E5RH24_HUMAN,tr|H0YBN4|H0YBN4_HUMAN,tr|E5RGH3|E5RGH3_HUMAN,tr|A0A087WTT1|A0A087WTT1_HUMAN,tr|A0A7I2YQ90|A0A7I2YQ90_HUMAN,tr|E7EQV3|E7EQV3_HUMAN" 17 2084.0076 1.75 86294 18157 3 2084.008398 695.6765 Polyadenylate-binding protein 4 OS=Homo sapiens OX=9606 GN=PABPC4 PE=1 SV=1 6.07 2940.4 - 9.39E+06 - - - 0.4059 - 3.778 0.614 - 493.9 1 2 0 0.0008 18 0 0 0 1.46E+08 8.32E+07 - - - 8.6951 1 221125_WJC_METTL3_EV_vs_WT_F06.18158.18158.4 5.10E-06 23/114 R.AIQINPAFADAHSNLASIHK.D sp|O15294|OGT1_HUMAN 1 2117.1018 1.95 86295 18158 4 2117.104754 530.2827 UDP-N-acetylglucosamine--peptide N-acetylglucosaminyltransferase 110 kDa subunit OS=Homo sapiens OX=9606 GN=OGT PE=1 SV=3 6.96 2940.5 - 2.60E+06 - - - 1.4014 - 4.083 0.567 - 399.3 1 2 0 0.003 20 0 0 0 6.38E+07 3.27E+07 - - - 4.6307 0.9998 221125_WJC_METTL3_EV_vs_WT_F06.18161.18161.4 5.21E-05 16/90 R.ALKDEEKMELQEIQLK.E "sp|P06753|TPM3_HUMAN,tr|A0A2R2Y2Q3|A0A2R2Y2Q3_HUMAN,tr|A0A087WWU8|A0A087WWU8_HUMAN,tr|J3KN67|J3KN67_HUMAN,tr|A0A494C0P6|A0A494C0P6_HUMAN" 5 1944.0238 1.26 86298 18161 4 1944.025691 487.0132 Tropomyosin alpha-3 chain OS=Homo sapiens OX=9606 GN=TPM3 PE=1 SV=2 4.59 2940.7 - 1.64E+06 - - - 0.9835 - 2.942 0.46 - 273.5 1 2 2 0.0019 16 0 0 0 2.69E+07 2.14E+07 - - - 3.6094 0.9938 221125_WJC_METTL3_EV_vs_WT_F06.18163.18163.2 5.91E-05 16/44 R.AAASSYNTQGAASSLGSYGAQAA.S sp|Q96PK6|RBM14_HUMAN 1 2102.9505 - 86300 18163 2 2102.949498 1052.4825 RNA-binding protein 14 OS=Homo sapiens OX=9606 GN=RBM14 PE=1 SV=2 5.57 2940.9 - 1.23E+06 - - - -0.4722 - 3.032 0.464 - 331.6 1 1 0 -0.001 23 0 0 0 - - - - - 5.1949 1 221125_WJC_METTL3_EV_vs_WT_F06.18164.18164.3 2.28E-11 17/60 R.ALKDEEKMELQEIQLK.E "sp|P06753|TPM3_HUMAN,tr|A0A2R2Y2Q3|A0A2R2Y2Q3_HUMAN,tr|A0A087WWU8|A0A087WWU8_HUMAN,tr|J3KN67|J3KN67_HUMAN,tr|A0A494C0P6|A0A494C0P6_HUMAN" 5 1944.0238 1.59 86301 18164 3 1944.025251 649.0152 Tropomyosin alpha-3 chain OS=Homo sapiens OX=9606 GN=TPM3 PE=1 SV=2 4.59 2941 - 1.21E+06 - - - 0.7572 - 3.744 0.587 - 368.5 1 2 2 0.0015 16 0 0 0 2.08E+07 1.30E+07 - - - 8.4714 1 221125_WJC_METTL3_EV_vs_WT_F06.18166.18166.3 1.37E-09 20/76 R.EQIVVDLSHPGVSEDDQVSR[166.11].L sp|O60701|UGDH_HUMAN 1 2218.0741 2.94 86303 18166 3 2218.071927 740.3653 UDP-glucose 6-dehydrogenase OS=Homo sapiens OX=9606 GN=UGDH PE=1 SV=1 4.1 2941.3 - 1.19E+06 - - - -0.9909 - 3.998 0.632 - 418.4 1 2 0 -0.0022 20 0 0 0 1.82E+07 6.20E+06 - - - 8.9475 0.9987 221125_WJC_METTL3_EV_vs_WT_F06.18167.18167.3 0.000445 17/60 R.DLKPQNLLIDDKGTIK.L "sp|P06493|CDK1_HUMAN,tr|E5RIU6|E5RIU6_HUMAN,tr|A0A024QZP7|A0A024QZP7_HUMAN,tr|A0A087WZZ9|A0A087WZZ9_HUMAN" 4 1810.02 1.07 86304 18167 3 1810.028705 604.3473 Cyclin-dependent kinase 1 OS=Homo sapiens OX=9606 GN=CDK1 PE=1 SV=3 6.04 2941.4 - 1.13E+06 - - - 4.8016 - 3.124 0.507 - 292.6 1 2 1 0.0087 16 0 0 0 1.36E+07 1.27E+07 - - - 7.113 1 221125_WJC_METTL3_EV_vs_WT_F06.18168.18168.2 1.10E-17 27/44 R.GNFGGSFAGSFGGAGGHAPGVAR.K "sp|P52272|HNRPM_HUMAN,tr|M0R2I7|M0R2I7_HUMAN,tr|M0QY96|M0QY96_HUMAN,tr|A0A087X0X3|A0A087X0X3_HUMAN" 4 2033.9456 1.8 86305 18168 2 2033.943842 1017.9801 Heterogeneous nuclear ribonucleoprotein M OS=Homo sapiens OX=9606 GN=HNRNPM PE=1 SV=3 9.76 2941.5 - 913960 - - - -0.8742 - 4.509 0.777 - 1642.1 1 2 0 -0.0018 23 0 0 0 7.61E+07 4.24E+07 - - - 8.4821 1 221125_WJC_METTL3_EV_vs_WT_F06.18170.18170.2 1.72E-13 24/44 R.GNFGGSFAGSFGGAGGHAPGVAR[166.11].K "sp|P52272|HNRPM_HUMAN,tr|M0R2I7|M0R2I7_HUMAN,tr|M0QY96|M0QY96_HUMAN,tr|A0A087X0X3|A0A087X0X3_HUMAN" 4 2043.9539 1.8 86307 18170 2 2043.950876 1022.9842 Heterogeneous nuclear ribonucleoprotein M OS=Homo sapiens OX=9606 GN=HNRNPM PE=1 SV=3 9.76 2941.8 - 643267 - - - -1.4746 - 4.368 0.778 - 1213.3 1 2 0 -0.003 23 0 0 0 7.61E+07 4.24E+07 - - - 8.411 0.9986 221125_WJC_METTL3_EV_vs_WT_F06.18171.18171.3 3.26E-08 14/96 Q.GSSLASYGNQPSSYGAQAASSYGVR[166.11].A sp|Q96PK6|RBM14_HUMAN 1 2474.1338 2.45 86308 18171 3 2474.135033 825.7185 RNA-binding protein 14 OS=Homo sapiens OX=9606 GN=RBM14 PE=1 SV=2 8.5 2941.9 - 626310 - - - 0.5125 - 2.988 0.602 - 146.9 1 1 0 0.0013 25 0 0 0 9.65E+06 3.93E+06 - - - 7.7696 1 221125_WJC_METTL3_EV_vs_WT_F06.18173.18173.2 1.04E-10 13/36 R.SVGDNSSDLSNVAVIDGNR.V "sp|O95163|ELP1_HUMAN,tr|A0A6Q8PFB7|A0A6Q8PFB7_HUMAN,tr|A0A6Q8PFH9|A0A6Q8PFH9_HUMAN,tr|A0A6Q8PH48|A0A6Q8PH48_HUMAN,tr|A0A6Q8PHC9|A0A6Q8PHC9_HUMAN,tr|A0A6Q8PHA0|A0A6Q8PHA0_HUMAN,tr|A0A6Q8PHI5|A0A6Q8PHI5_HUMAN,tr|A0A6Q8PF69|A0A6Q8PF69_HUMAN,tr|A0A6Q8PF66|A0A6Q8PF66_HUMAN,tr|A0A6Q8PGW3|A0A6Q8PGW3_HUMAN,tr|A0A6Q8PG86|A0A6Q8PG86_HUMAN,tr|A0A6Q8PGR0|A0A6Q8PGR0_HUMAN,tr|A0A6Q8PEX6|A0A6Q8PEX6_HUMAN,tr|F5H2T0|F5H2T0_HUMAN,tr|A0A6Q8PHF4|A0A6Q8PHF4_HUMAN,tr|A0A6Q8PFN8|A0A6Q8PFN8_HUMAN" 16 1917.9028 1.13 86310 18173 2 1917.906115 959.9587 Elongator complex protein 1 OS=Homo sapiens OX=9606 GN=ELP1 PE=1 SV=3 3.93 2942.1 - 204308 - - - 1.7222 - 2.464 0.658 - 142.4 1 2 0 0.0033 19 0 0 0 4.30E+06 3.79E+06 - - - 6.117 1 221125_WJC_METTL3_EV_vs_WT_F06.18176.18176.4 2.46E-06 17/114 R.AIQINPAFADAHSNLASIHK[136.11].D sp|O15294|OGT1_HUMAN 1 2125.116 1.95 86311 18176 4 2125.112241 532.2863 UDP-N-acetylglucosamine--peptide N-acetylglucosaminyltransferase 110 kDa subunit OS=Homo sapiens OX=9606 GN=OGT PE=1 SV=3 6.96 2942.5 - 4.06E+06 - - - -1.7627 - 3.502 0.521 - 188.1 1 2 0 -0.0037 20 0 0 0 6.38E+07 3.27E+07 - - - 4.1788 1 221125_WJC_METTL3_EV_vs_WT_F06.18177.18177.4 3.26E-12 24/132 R.GNFGGSFAGSFGGAGGHAPGVAR[166.11].K "sp|P52272|HNRPM_HUMAN,tr|M0R2I7|M0R2I7_HUMAN,tr|M0QY96|M0QY96_HUMAN,tr|A0A087X0X3|A0A087X0X3_HUMAN" 4 2043.9539 2.15 86312 18177 4 2043.952218 511.9957 Heterogeneous nuclear ribonucleoprotein M OS=Homo sapiens OX=9606 GN=HNRNPM PE=1 SV=3 9.76 2942.6 - 2.38E+06 - - - -0.818 - 4.373 0.557 - 357.9 1 2 0 -0.0017 23 0 0 0 4.95E+07 2.31E+07 - - - 4.5517 1 221125_WJC_METTL3_EV_vs_WT_F06.18179.18179.3 1.81E-08 22/72 R.GSDALSETSSVSHIEDLEK.V "sp|Q6P996|PDXD1_HUMAN,tr|H3BND4|H3BND4_HUMAN" 2 2002.9331 1.72 86314 18179 3 2002.933502 668.6516 Pyridoxal-dependent decarboxylase domain-containing protein 1 OS=Homo sapiens OX=9606 GN=PDXDC1 PE=1 SV=2 4.17 2942.7 - 3.49E+06 - - - 0.1962 - 4.323 0.587 - 729.7 1 2 0 0.0004 19 0 0 0 8.59E+07 4.98E+07 - - - 8.681 1 221125_WJC_METTL3_EV_vs_WT_F06.18181.18181.2 4.73E-12 16/36 R.SVGDNSSDLSNVAVIDGNR[166.11].V "sp|O95163|ELP1_HUMAN,tr|A0A6Q8PFB7|A0A6Q8PFB7_HUMAN,tr|A0A6Q8PFH9|A0A6Q8PFH9_HUMAN,tr|A0A6Q8PH48|A0A6Q8PH48_HUMAN,tr|A0A6Q8PHC9|A0A6Q8PHC9_HUMAN,tr|A0A6Q8PHA0|A0A6Q8PHA0_HUMAN,tr|A0A6Q8PHI5|A0A6Q8PHI5_HUMAN,tr|A0A6Q8PF69|A0A6Q8PF69_HUMAN,tr|A0A6Q8PF66|A0A6Q8PF66_HUMAN,tr|A0A6Q8PGW3|A0A6Q8PGW3_HUMAN,tr|A0A6Q8PG86|A0A6Q8PG86_HUMAN,tr|A0A6Q8PGR0|A0A6Q8PGR0_HUMAN,tr|A0A6Q8PEX6|A0A6Q8PEX6_HUMAN,tr|F5H2T0|F5H2T0_HUMAN,tr|A0A6Q8PHF4|A0A6Q8PHF4_HUMAN,tr|A0A6Q8PFN8|A0A6Q8PFN8_HUMAN" 16 1927.9111 1.13 86316 18181 2 1927.907965 964.9628 Elongator complex protein 1 OS=Homo sapiens OX=9606 GN=ELP1 PE=1 SV=3 3.93 2942.9 - 406108 - - - -1.6168 - 3.371 0.69 - 730.8 1 2 0 -0.0031 19 0 0 0 4.30E+06 3.79E+06 - - - 7.124 0.9994 221125_WJC_METTL3_EV_vs_WT_F06.18184.18184.4 0.00463 12/120 R.EGDYVLFHHEGGVDVGDVDAK.A sp|P53396|ACLY_HUMAN 1 2257.0287 0.59 86317 18184 4 2257.029374 565.2645 ATP-citrate synthase OS=Homo sapiens OX=9606 GN=ACLY PE=1 SV=3 4.22 2943.3 - 3.03E+06 - - - 0.2805 - 1.922 0.324 - 84.8 1 2 0 0.0006 21 0 0 0 3.14E+07 5.28E+07 - - - 2.2619 1 221125_WJC_METTL3_EV_vs_WT_F06.18188.18188.3 1.45E-10 20/80 R.EGDYVLFHHEGGVDVGDVDAK[136.11].A sp|P53396|ACLY_HUMAN 1 2265.0429 0.58 86321 18188 3 2265.042287 756.0216 ATP-citrate synthase OS=Homo sapiens OX=9606 GN=ACLY PE=1 SV=3 4.22 2943.6 - 1.26E+06 - - - -0.2887 - 3.609 0.606 - 448.4 1 2 0 -0.0007 21 0 0 0 1.03E+07 1.75E+07 - - - 8.3731 1 221125_WJC_METTL3_EV_vs_WT_F06.18194.18194.3 4.30E-10 17/84 R.VSSPLPSPSAMTDAANSQAAAK.L "sp|Q8WXI9|P66B_HUMAN,tr|A0A0U1RRM1|A0A0U1RRM1_HUMAN,tr|A0A0U1RR30|A0A0U1RR30_HUMAN" 3 2100.0157 1.91 86325 18194 3 2100.016679 701.0125 Transcriptional repressor p66-beta OS=Homo sapiens OX=9606 GN=GATAD2B PE=1 SV=1 5.81 2944.3 - 5.19E+06 - - - 0.45 - 3.556 0.624 - 420.5 1 2 0 0.0009 22 0 0 0 2.26E+08 1.18E+08 - - - 8.5044 1 221125_WJC_METTL3_EV_vs_WT_F06.18196.18196.3 1.53E-13 17/96 K.LVQDVANNTNEEAGDGTTTATVLAR.S "sp|P10809|CH60_HUMAN,tr|C9JL25|C9JL25_HUMAN,tr|A0A7I2V2X6|A0A7I2V2X6_HUMAN,tr|A0A7I2YQK6|A0A7I2YQK6_HUMAN,tr|A0A7I2V599|A0A7I2V599_HUMAN,tr|E7EXB4|E7EXB4_HUMAN,tr|A0A7I2YQ71|A0A7I2YQ71_HUMAN,tr|E7ESH4|E7ESH4_HUMAN,tr|A0A7I2V5M1|A0A7I2V5M1_HUMAN,tr|A0A7I2V5K3|A0A7I2V5K3_HUMAN,tr|A0A7I2V369|A0A7I2V369_HUMAN" 11 2559.2413 1.52 86327 18196 3 2559.242699 854.0877 "60 kDa heat shock protein, mitochondrial OS=Homo sapiens OX=9606 GN=HSPD1 PE=1 SV=2" 3.92 2944.6 - 1.46E+06 - - - 0.565 - 3.646 0.705 - 346.1 1 2 0 0.0014 25 0 0 0 4.53E+07 2.98E+07 - - - 9.3758 0.9647 221125_WJC_METTL3_EV_vs_WT_F06.18199.18199.4 0.000615 16/120 R.EGDYVLFHHEGGVDVGDVDAK[136.11].A sp|P53396|ACLY_HUMAN 1 2265.0429 0.59 86328 18199 4 2266.040483 567.268 ATP-citrate synthase OS=Homo sapiens OX=9606 GN=ACLY PE=1 SV=3 4.22 2945 - 2.68E+06 - - - 440.4075 - 2.323 0.358 - 141.9 1 2 0 0.9975 21 0 0 0 3.15E+07 5.34E+07 - - - 2.3444 1 221125_WJC_METTL3_EV_vs_WT_F06.18200.18200.2 2.85E-12 18/42 R.VSSPLPSPSAMTDAANSQAAAK[136.11].L "sp|Q8WXI9|P66B_HUMAN,tr|A0A0U1RRM1|A0A0U1RRM1_HUMAN,tr|A0A0U1RR30|A0A0U1RR30_HUMAN" 3 2108.0299 2.19 86329 18200 2 2108.037105 1055.0222 Transcriptional repressor p66-beta OS=Homo sapiens OX=9606 GN=GATAD2B PE=1 SV=1 5.81 2945.1 - 805551 - - - 3.4018 - 3.538 0.623 - 671 1 2 0 0.0072 22 0 0 0 6.98E+07 3.19E+07 - - - 6.7468 0.9994 221125_WJC_METTL3_EV_vs_WT_F06.18202.18202.3 0.00433 16/76 R.GVSSQETAGIGASAHLVNFK[136.11].G "sp|P43490|NAMPT_HUMAN,tr|A0A7P0T862|A0A7P0T862_HUMAN,tr|B7Z8W6|B7Z8W6_HUMAN,tr|A0A7P0T931|A0A7P0T931_HUMAN,tr|A0A7P0T8L3|A0A7P0T8L3_HUMAN,tr|A0A7P0T941|A0A7P0T941_HUMAN,tr|A0A7P0T973|A0A7P0T973_HUMAN,tr|A0A7P0T895|A0A7P0T895_HUMAN,tr|A0A7P0TBB7|A0A7P0TBB7_HUMAN,tr|A0A7P0TA73|A0A7P0TA73_HUMAN,tr|A0A0C4DFS8|A0A0C4DFS8_HUMAN,tr|A0A7P0TAS5|A0A7P0TAS5_HUMAN,tr|A0A7P0T9I9|A0A7P0T9I9_HUMAN,tr|A0A7P0Z466|A0A7P0Z466_HUMAN,tr|A0A7P0T8D2|A0A7P0T8D2_HUMAN" 15 1980.0156 0.48 86331 18202 3 1980.016379 661.0125 Nicotinamide phosphoribosyltransferase OS=Homo sapiens OX=9606 GN=NAMPT PE=1 SV=1 6.75 2945.3 - 1.34E+06 - - - 0.3914 - 2.151 0.291 - 117.1 1 2 0 0.0008 20 0 0 0 7.59E+06 1.58E+07 - - - 3.6423 1 221125_WJC_METTL3_EV_vs_WT_F06.18203.18203.3 1.37E-08 15/52 K.HWPFMVVNDAGR[166.11]PK[136.11].V "sp|P11142|HSP7C_HUMAN,tr|E9PQQ4|E9PQQ4_HUMAN,tr|E9PNE6|E9PNE6_HUMAN,tr|E9PKE3|E9PKE3_HUMAN,tr|E9PN89|E9PN89_HUMAN,tr|E9PLF4|E9PLF4_HUMAN,tr|E9PK54|E9PK54_HUMAN,tr|E9PN25|E9PN25_HUMAN,tr|E9PPY6|E9PPY6_HUMAN,tr|E9PQK7|E9PQK7_HUMAN" 10 1670.847 0.1 86332 18203 3 1670.849678 557.9563 Heat shock cognate 71 kDa protein OS=Homo sapiens OX=9606 GN=HSPA8 PE=1 SV=1 8.75 2945.4 - 774596 - - - 1.5812 - 2.766 0.551 - 293.4 1 2 0 0.0026 14 0 0 0 1.75E+07 1.79E+08 - - - 7.3862 1 221125_WJC_METTL3_EV_vs_WT_F06.18208.18208.3 5.09E-10 21/68 K.YVHYEIDAC[160.03]MDSEAPGSK[136.11].D "sp|Q86U44|MTA70_HUMAN,tr|H0YFV6|H0YFV6_HUMAN" 2 2078.8805 0.01 86335 18208 3 2079.873608 693.9674 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 4.31 2946 - 5.70E+06 - - - 477.7167 - 3.614 0.724 - 455.6 1 2 0 0.9931 18 0 0 0 1.53E+06 1.84E+08 - - - 9.5361 0.9999 221125_WJC_METTL3_EV_vs_WT_F06.18210.18210.4 5.45E-07 21/96 R.GGSPFAIVITQQHQIHR.S sp|Q9HCD5|NCOA5_HUMAN 1 1888.0068 1.7 86337 18210 4 1888.001945 473.009 Nuclear receptor coactivator 5 OS=Homo sapiens OX=9606 GN=NCOA5 PE=1 SV=2 9.76 2946.2 - 1.21E+06 - - - -2.5524 - 3.679 0.505 - 393.8 1 2 0 -0.0048 17 0 0 0 1.59E+08 9.37E+07 - - - 4.0725 0.9994 221125_WJC_METTL3_EV_vs_WT_F06.18214.18214.3 3.40E-05 18/72 K.NAGQAVTIVAQYRPEEYSR.F "sp|Q12959|DLG1_HUMAN,tr|A0A590UJ18|A0A590UJ18_HUMAN,tr|A0A590UKA8|A0A590UKA8_HUMAN,tr|A0A590UK48|A0A590UK48_HUMAN,tr|A0A590UK70|A0A590UK70_HUMAN,tr|A0A0C4DFT3|A0A0C4DFT3_HUMAN,tr|A0A590UJD9|A0A590UJD9_HUMAN,tr|A0A590UJL2|A0A590UJL2_HUMAN,tr|A0A590UJ25|A0A590UJ25_HUMAN,tr|A0A590UJX2|A0A590UJX2_HUMAN,tr|A0A590UJ08|A0A590UJ08_HUMAN,tr|C9JUA9|C9JUA9_HUMAN,tr|A0A590UJ68|A0A590UJ68_HUMAN,tr|A0A590UK81|A0A590UK81_HUMAN,tr|E7EQD7|E7EQD7_HUMAN,tr|A0A590UJ81|A0A590UJ81_HUMAN,tr|A0A590UJR4|A0A590UJR4_HUMAN,tr|A0A590UJC5|A0A590UJC5_HUMAN,tr|A0A590UK02|A0A590UK02_HUMAN,tr|A0A590UJ64|A0A590UJ64_HUMAN,tr|A0A590UJ29|A0A590UJ29_HUMAN,tr|A0A590UJS9|A0A590UJS9_HUMAN,tr|A0A590UJR5|A0A590UJR5_HUMAN" 23 2151.0709 0.61 86339 18214 3 2151.07045 718.0309 Disks large homolog 1 OS=Homo sapiens OX=9606 GN=DLG1 PE=1 SV=2 6.14 2946.6 - 892346 - - - -0.2004 - 2.507 0.259 - 336.7 1 2 0 -0.0004 19 0 0 0 2.33E+07 3.80E+07 - - - 3.6855 1 221125_WJC_METTL3_EV_vs_WT_F06.18229.18229.3 7.27E-07 16/56 R.EAEDTQVFGDLPR[166.11]PR[166.11].L sp|Q96B36|AKTS1_HUMAN 1 1748.8597 0.94 86350 18229 3 1748.858061 583.9605 Proline-rich AKT1 substrate 1 OS=Homo sapiens OX=9606 GN=AKT1S1 PE=1 SV=1 4.32 2948.5 - 878803 - - - -0.9097 - 3.01 0.526 - 425.1 1 2 0 -0.0016 15 0 0 0 1.33E+07 1.41E+07 - - - 7.2793 0.9997 221125_WJC_METTL3_EV_vs_WT_F06.18232.18232.4 6.88E-06 19/102 R.NLHVVFTMNPSSEGLKDR.A "sp|Q14204|DYHC1_HUMAN,tr|A0A7P0T8N2|A0A7P0T8N2_HUMAN,tr|A0A7P0T9C4|A0A7P0T9C4_HUMAN,tr|A0A7P0TBJ7|A0A7P0TBJ7_HUMAN,tr|A0A7P0T9K2|A0A7P0T9K2_HUMAN,tr|A0A2R8Y706|A0A2R8Y706_HUMAN,tr|A0A7P0T916|A0A7P0T916_HUMAN,tr|A0A7P0TB75|A0A7P0TB75_HUMAN,tr|A0A7P0T8W5|A0A7P0T8W5_HUMAN,tr|A0A7P0TAF3|A0A7P0TAF3_HUMAN,tr|A0A7P0T9F1|A0A7P0T9F1_HUMAN,tr|A0A7P0TAW9|A0A7P0TAW9_HUMAN,tr|A0A7P0TA13|A0A7P0TA13_HUMAN,tr|A0A7P0T7V5|A0A7P0T7V5_HUMAN,tr|A0A7P0T9R4|A0A7P0T9R4_HUMAN,tr|A0A2R8Y5T0|A0A2R8Y5T0_HUMAN,tr|A0A2R8YFZ7|A0A2R8YFZ7_HUMAN,tr|A0A7P0T825|A0A7P0T825_HUMAN,tr|A0A2R8Y6H2|A0A2R8Y6H2_HUMAN,tr|A0A7P0TAM4|A0A7P0TAM4_HUMAN" 20 2043.0208 0.89 86353 18232 4 2043.022343 511.7625 Cytoplasmic dynein 1 heavy chain 1 OS=Homo sapiens OX=9606 GN=DYNC1H1 PE=1 SV=5 6.75 2948.9 - 773688 - - - 0.7753 - 3.395 0.429 - 288.9 1 2 1 0.0016 18 0 0 0 1.13E+07 1.27E+07 - - - 3.3783 0.9998 221125_WJC_METTL3_EV_vs_WT_F06.18237.18237.4 4.77E-05 21/96 R.GGSPFAIVITQQHQIHR[166.11].S sp|Q9HCD5|NCOA5_HUMAN 1 1898.015 1.33 86356 18237 4 1898.013768 475.511 Nuclear receptor coactivator 5 OS=Homo sapiens OX=9606 GN=NCOA5 PE=1 SV=2 9.76 2949.5 - 1.60E+06 - - - -0.667 - 3.27 0.362 - 395.8 1 2 0 -0.0013 17 0 0 0 3.04E+07 2.29E+07 - - - 2.7879 0.9999 221125_WJC_METTL3_EV_vs_WT_F06.18245.18245.2 0.000634 14/22 R.TVIIEQSWGSPK.V "sp|P10809|CH60_HUMAN,tr|C9JL25|C9JL25_HUMAN,tr|A0A7I2V2X6|A0A7I2V2X6_HUMAN,tr|A0A7I2YQK6|A0A7I2YQK6_HUMAN,tr|A0A7I2V599|A0A7I2V599_HUMAN,tr|E7EXB4|E7EXB4_HUMAN,tr|C9JL19|C9JL19_HUMAN,tr|A0A7I2YQ71|A0A7I2YQ71_HUMAN,tr|E7ESH4|E7ESH4_HUMAN,tr|A0A7I2V5M1|A0A7I2V5M1_HUMAN,tr|A0A7I2V5K3|A0A7I2V5K3_HUMAN,tr|A0A7I2V369|A0A7I2V369_HUMAN,tr|C9JCQ4|C9JCQ4_HUMAN" 13 1343.7085 1.3 86362 18245 2 1343.707944 672.8615 "60 kDa heat shock protein, mitochondrial OS=Homo sapiens OX=9606 GN=HSPD1 PE=1 SV=2" 5.66 2950.5 - 1.90E+06 - - - -0.4257 - 2.818 0.475 - 660.7 1 2 0 -0.0006 12 0 0 0 4.61E+07 3.55E+07 - - - 5.2751 1 221125_WJC_METTL3_EV_vs_WT_F06.18247.18247.4 3.60E-09 17/78 K.HWPFMVVNDAGR[166.11]PK[136.11].V "sp|P11142|HSP7C_HUMAN,tr|E9PQQ4|E9PQQ4_HUMAN,tr|E9PNE6|E9PNE6_HUMAN,tr|E9PKE3|E9PKE3_HUMAN,tr|E9PN89|E9PN89_HUMAN,tr|E9PLF4|E9PLF4_HUMAN,tr|E9PK54|E9PK54_HUMAN,tr|E9PN25|E9PN25_HUMAN,tr|E9PPY6|E9PPY6_HUMAN,tr|E9PQK7|E9PQK7_HUMAN" 10 1670.847 0.09 86364 18247 4 1670.84556 418.719 Heat shock cognate 71 kDa protein OS=Homo sapiens OX=9606 GN=HSPA8 PE=1 SV=1 8.75 2950.7 - 909491 - - - -0.8834 - 2.612 0.551 - 236.6 1 2 0 -0.0015 14 0 0 0 5.38E+06 5.73E+07 - - - 4.3709 1 221125_WJC_METTL3_EV_vs_WT_F06.18250.18250.3 1.46E-06 20/56 R.EAEDTQVFGDLPRPR.L sp|Q96B36|AKTS1_HUMAN 1 1728.8431 1.1 86365 18250 3 1728.843825 577.2883 Proline-rich AKT1 substrate 1 OS=Homo sapiens OX=9606 GN=AKT1S1 PE=1 SV=1 4.32 2951.1 - 1.13E+06 - - - 0.4124 - 3.331 0.536 - 741.1 1 2 0 0.0007 15 0 0 0 8.77E+07 7.97E+07 - - - 7.6555 1 221125_WJC_METTL3_EV_vs_WT_F06.18252.18252.4 1.12E-10 19/114 R.VHLDIQVGEHANDYAEIAAK.D sp|Q9BVK6|TMED9_HUMAN 1 2192.0862 1.27 86367 18252 4 2192.086096 549.0288 Transmembrane emp24 domain-containing protein 9 OS=Homo sapiens OX=9606 GN=TMED9 PE=1 SV=2 4.72 2951.4 - 1.78E+06 - - - -0.0456 - 3.726 0.632 - 280 1 2 0 -0.0001 20 0 0 0 3.26E+07 2.56E+07 - - - 5.1666 0.9999 221125_WJC_METTL3_EV_vs_WT_F06.18253.18253.4 1.02E-07 19/114 R.VHLDIQVGEHANDYAEIAAK[136.11].D sp|Q9BVK6|TMED9_HUMAN 1 2200.1004 1.26 86368 18253 4 2200.093413 551.0324 Transmembrane emp24 domain-containing protein 9 OS=Homo sapiens OX=9606 GN=TMED9 PE=1 SV=2 4.72 2951.5 - 1.55E+06 - - - -3.1739 - 3.696 0.543 - 281.8 1 2 0 -0.007 20 0 0 0 3.24E+07 2.56E+07 - - - 4.3874 0.9999 221125_WJC_METTL3_EV_vs_WT_F06.18254.18254.4 1.51E-05 17/78 K.YKDDPVDLRLDIER.R "sp|Q9Y2W1|TR150_HUMAN,tr|A0A3B3ITZ9|A0A3B3ITZ9_HUMAN" 2 1745.8948 2.28 86369 18254 4 1745.892786 437.481 Thyroid hormone receptor-associated protein 3 OS=Homo sapiens OX=9606 GN=THRAP3 PE=1 SV=2 4.36 2951.6 - 1.36E+06 - - - -1.1616 - 2.866 0.515 - 261.1 1 2 2 -0.002 14 0 0 0 9.95E+07 4.36E+07 - - - 4.0912 0.9999 221125_WJC_METTL3_EV_vs_WT_F06.18256.18256.3 6.50E-06 17/64 R.GGSPFAIVITQQHQIHR[166.11].S sp|Q9HCD5|NCOA5_HUMAN 1 1898.015 1.8 86371 18256 3 1898.014209 633.679 Nuclear receptor coactivator 5 OS=Homo sapiens OX=9606 GN=NCOA5 PE=1 SV=2 9.76 2951.9 - 653754 - - - -0.4347 - 3.554 0.309 - 446.2 1 2 0 -0.0008 17 0 0 0 5.58E+07 3.10E+07 - - - 5.1884 0.9974 221125_WJC_METTL3_EV_vs_WT_F06.18257.18257.3 2.25E-05 13/68 R.ILNNGHAFNVEFDDSQDK[136.11].A "sp|P00918|CAH2_HUMAN,tr|E5RID5|E5RID5_HUMAN,tr|E5RK37|E5RK37_HUMAN" 3 2069.9534 0.99 86372 18257 3 2070.958601 690.9917 Carbonic anhydrase 2 OS=Homo sapiens OX=9606 GN=CA2 PE=1 SV=2 4.22 2952 - 555691 - - - 485.6162 - 2.198 0.461 - 189.3 1 2 0 1.0052 18 0 0 0 1.76E+07 1.78E+07 - - - 5.3623 0.986 221125_WJC_METTL3_EV_vs_WT_F06.18258.18258.4 0.49 13/108 K.GFEK[136.11]PTENSSAVLLQWHEK[136.11].A sp|Q9BPX5|ARP5L_HUMAN 1 2215.1244 2.98 86373 18258 4 2215.119014 554.7884 Actin-related protein 2\3 complex subunit 5-like protein OS=Homo sapiens OX=9606 GN=ARPC5L PE=1 SV=1 5.5 2952.1 - 551135 - - - -2.4464 - 2.233 0.207 - 102.5 1 2 0 -0.0054 19 0 0 0 1.66E+07 5.59E+06 - - - 1.298 1 221125_WJC_METTL3_EV_vs_WT_F06.18262.18262.3 2.91E-10 21/72 R.REEGAPGDPEAALEDNLAR.L sp|P33908|MA1A1_HUMAN 1 2008.945 4.56 86375 18262 3 2008.941475 670.6556 "Mannosyl-oligosaccharide 1,2-alpha-mannosidase IA OS=Homo sapiens OX=9606 GN=MAN1A1 PE=1 SV=3" 4.08 2952.6 - 856705 - - - -1.7601 - 3.394 0.628 - 477.5 1 2 0 -0.0035 19 0 0 0 5.77E+07 1.26E+07 - - - 8.5428 0.9993 221125_WJC_METTL3_EV_vs_WT_F06.18264.18264.3 0.00196 14/52 K.YKDDPVDLRLDIER.R "sp|Q9Y2W1|TR150_HUMAN,tr|A0A3B3ITZ9|A0A3B3ITZ9_HUMAN" 2 1745.8948 1.79 86377 18264 3 1745.896911 582.9722 Thyroid hormone receptor-associated protein 3 OS=Homo sapiens OX=9606 GN=THRAP3 PE=1 SV=2 4.36 2952.8 - 1.72E+06 - - - 1.2011 - 1.961 0.414 - 223.9 1 2 2 0.0021 14 0 0 0 6.09E+07 3.40E+07 - - - 4.9448 0.9998 221125_WJC_METTL3_EV_vs_WT_F06.18265.18265.4 1.13E-07 14/84 R.FYHDWNDKEIEVLNK.H "sp|Q9NTK5|OLA1_HUMAN,tr|C9JCJ9|C9JCJ9_HUMAN,tr|J3KQ32|J3KQ32_HUMAN" 3 1948.9319 0.93 86378 18265 4 1948.931397 488.2403 Obg-like ATPase 1 OS=Homo sapiens OX=9606 GN=OLA1 PE=1 SV=2 4.75 2952.9 - 1.19E+06 - - - -0.2719 - 2.708 0.475 - 183.5 1 2 1 -0.0005 15 0 0 0 1.16E+07 1.25E+07 - - - 3.7167 1 221125_WJC_METTL3_EV_vs_WT_F06.18266.18266.3 7.60E-11 17/76 R.VHLDIQVGEHANDYAEIAAK[136.11].D sp|Q9BVK6|TMED9_HUMAN 1 2200.1004 0.91 86379 18266 3 2200.098738 734.3741 Transmembrane emp24 domain-containing protein 9 OS=Homo sapiens OX=9606 GN=TMED9 PE=1 SV=2 4.72 2953.1 - 656047 - - - -0.7536 - 3.624 0.627 - 235.9 1 2 0 -0.0017 20 0 0 0 1.09E+07 1.20E+07 - - - 8.6537 0.9578 221125_WJC_METTL3_EV_vs_WT_F06.18269.18269.4 0.017 Sep-72 R.QIEETLAHFHLTK[136.11].D sp|P19367|HXK1_HUMAN 1 1573.8344 1.34 86382 18269 4 1573.832668 394.4659 Hexokinase-1 OS=Homo sapiens OX=9606 GN=HK1 PE=1 SV=3 6 2953.5 - 260118 - - - -1.0954 - 1.514 0.149 - 45.4 1 2 0 -0.0017 13 0 0 0 1.19E+06 8.95E+05 - - - 0.6762 1 221125_WJC_METTL3_EV_vs_WT_F06.18274.18274.4 1.67E-06 17/108 R.GLLQDDAHPTLVTYADHSK[136.11].L "sp|Q86U44|MTA70_HUMAN,tr|F5H6D8|F5H6D8_HUMAN,tr|H0YFV6|H0YFV6_HUMAN,tr|B4DTN4|B4DTN4_HUMAN" 4 2088.0367 0.02 86385 18274 4 2088.035527 523.0165 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 5.13 2953.9 - 5.46E+06 - - - -0.5776 - 3.133 0.55 - 261 1 2 0 -0.0012 19 0 0 0 3.22E+06 1.53E+08 - - - 4.3992 0.9997 221125_WJC_METTL3_EV_vs_WT_F06.18275.18275.4 0.00223 14/78 K.YK[136.11]DDPVDLR[166.11]LDIER[166.11].R "sp|Q9Y2W1|TR150_HUMAN,tr|A0A3B3ITZ9|A0A3B3ITZ9_HUMAN" 2 1773.9256 2.28 86386 18275 4 1773.923604 444.4887 Thyroid hormone receptor-associated protein 3 OS=Homo sapiens OX=9606 GN=THRAP3 PE=1 SV=2 4.36 2954 - 2.08E+06 - - - -1.0993 - 2.825 0.444 - 190.5 1 2 2 -0.0019 14 0 0 0 9.95E+07 4.36E+07 - - - 3.468 1 221125_WJC_METTL3_EV_vs_WT_F06.18278.18278.3 3.05E-11 22/96 K.LVQDVANNTNEEAGDGTTTATVLAR[166.11].S "sp|P10809|CH60_HUMAN,tr|C9JL25|C9JL25_HUMAN,tr|A0A7I2V2X6|A0A7I2V2X6_HUMAN,tr|A0A7I2YQK6|A0A7I2YQK6_HUMAN,tr|A0A7I2V599|A0A7I2V599_HUMAN,tr|E7EXB4|E7EXB4_HUMAN,tr|A0A7I2YQ71|A0A7I2YQ71_HUMAN,tr|E7ESH4|E7ESH4_HUMAN,tr|A0A7I2V5M1|A0A7I2V5M1_HUMAN,tr|A0A7I2V5K3|A0A7I2V5K3_HUMAN,tr|A0A7I2V369|A0A7I2V369_HUMAN" 11 2569.2495 1.29 86389 18278 3 2569.248058 857.4238 "60 kDa heat shock protein, mitochondrial OS=Homo sapiens OX=9606 GN=HSPD1 PE=1 SV=2" 3.92 2954.4 - 1.02E+06 - - - -0.5702 - 4.056 0.662 - 740.2 1 2 0 -0.0015 25 0 0 0 3.58E+07 2.77E+07 - - - 9.1416 0.9847 221125_WJC_METTL3_EV_vs_WT_F06.18281.18281.4 0.0189 15/108 R.VNQLGGVFINGRPLPNHIR.H "sp|P23760|PAX3_HUMAN,sp|P23759|PAX7_HUMAN" 2 2100.1705 1.59 86392 18281 4 2100.178153 526.0499 Paired box protein Pax-3 OS=Homo sapiens OX=9606 GN=PAX3 PE=1 SV=2 12 2954.7 - 373096 - - - 3.6559 - 2.217 0.242 - 95.8 1 2 0 0.0077 19 0 0 0 5.19E+06 3.25E+06 - - - 1.5996 1 221125_WJC_METTL3_EV_vs_WT_F06.18285.18285.3 8.85E-09 19/64 R.GGSPFAIVITQQHQIHR.S sp|Q9HCD5|NCOA5_HUMAN 1 1888.0068 1.81 86394 18285 3 1888.006127 630.3429 Nuclear receptor coactivator 5 OS=Homo sapiens OX=9606 GN=NCOA5 PE=1 SV=2 9.76 2955.2 - 1.15E+06 - - - -0.3374 - 3.848 0.503 - 667.4 1 2 0 -0.0006 17 0 0 0 5.62E+07 3.11E+07 - - - 7.5521 1 221125_WJC_METTL3_EV_vs_WT_F06.18286.18286.3 9.36E-14 26/80 R.GENLVSMTVEGPPPKDTGIAR.V "sp|P63162|RSMN_HUMAN,sp|P14678|RSMB_HUMAN,tr|J3QLE5|J3QLE5_HUMAN" 3 2167.0943 1.15 86395 18286 3 2167.092988 723.372 Small nuclear ribonucleoprotein-associated protein N OS=Homo sapiens OX=9606 GN=SNRPN PE=1 SV=1 4.68 2955.4 - 1.15E+06 - - - -0.6137 - 4.558 0.591 - 1060 1 2 1 -0.0013 21 0 0 0 2.28E+07 1.98E+07 - - - 8.7654 1 221125_WJC_METTL3_EV_vs_WT_F06.18287.18287.3 4.25E-06 18/52 K.R[166.11]FGDDLNHISC[160.03]VIK[136.11].E "sp|Q8IXM2|BAP18_HUMAN,tr|H0YIS7|H0YIS7_HUMAN,tr|F8W038|F8W038_HUMAN,tr|F8W1H0|F8W1H0_HUMAN" 4 1690.858 3.24 86396 18287 3 1690.857649 564.6266 Chromatin complexes subunit BAP18 OS=Homo sapiens OX=9606 GN=BAP18 PE=1 SV=1 6.74 2955.5 - 898388 - - - -0.2046 - 3.269 0.535 - 623.7 1 2 0 -0.0003 14 0 0 0 7.91E+07 2.44E+07 - - - 7.6524 0.9999 221125_WJC_METTL3_EV_vs_WT_F06.18288.18288.4 6.07E-09 19/108 K.FKDDVMPATYC[160.03]EIDLDKEK.R "sp|Q9HD45|TM9S3_HUMAN,tr|Q5TB53|Q5TB53_HUMAN" 2 2316.0654 1.55 86397 18288 4 2316.064722 580.0236 Transmembrane 9 superfamily member 3 OS=Homo sapiens OX=9606 GN=TM9SF3 PE=1 SV=2 4.23 2955.6 - 611552 - - - -0.2867 - 3.458 0.506 - 358.4 1 2 2 -0.0007 19 0 0 0 4.74E+07 3.06E+07 - - - 4.0497 1 221125_WJC_METTL3_EV_vs_WT_F06.18293.18293.4 3.47E-08 14/78 K.R[166.11]FGDDLNHISC[160.03]VIK[136.11].E "sp|Q8IXM2|BAP18_HUMAN,tr|H0YIS7|H0YIS7_HUMAN,tr|F8W038|F8W038_HUMAN,tr|F8W1H0|F8W1H0_HUMAN" 4 1690.858 3.63 86402 18293 4 1690.859088 423.7218 Chromatin complexes subunit BAP18 OS=Homo sapiens OX=9606 GN=BAP18 PE=1 SV=1 6.74 2956.3 - 366147 - - - 0.6464 - 2.577 0.535 - 240.3 1 2 0 0.0011 14 0 0 0 3.35E+07 9.23E+06 - - - 4.2269 0.9992 221125_WJC_METTL3_EV_vs_WT_F06.18298.18298.3 0.000756 13/52 K.YK[136.11]DDPVDLR[166.11]LDIER[166.11].R "sp|Q9Y2W1|TR150_HUMAN,tr|A0A3B3ITZ9|A0A3B3ITZ9_HUMAN" 2 1773.9256 1.8 86405 18298 3 1773.927451 592.3158 Thyroid hormone receptor-associated protein 3 OS=Homo sapiens OX=9606 GN=THRAP3 PE=1 SV=2 4.36 2956.8 - 1.86E+06 - - - 1.0694 - 1.904 0.409 - 191.8 1 2 2 0.0019 14 0 0 0 6.13E+07 3.41E+07 - - - 4.8108 0.9986 221125_WJC_METTL3_EV_vs_WT_F06.18299.18299.3 0.00773 13/52 K.SFFDNISC[160.03]DDNR[166.11]ER[166.11].R "sp|Q8ND56|LS14A_HUMAN,tr|A0A096LP11|A0A096LP11_HUMAN,tr|A0A140TA76|A0A140TA76_HUMAN,tr|A0A0G2JQ95|A0A0G2JQ95_HUMAN" 4 1793.7542 1.54 86406 18299 3 1793.745206 598.9253 Protein LSM14 homolog A OS=Homo sapiens OX=9606 GN=LSM14A PE=1 SV=3 4.23 2956.9 - 1.45E+06 - - - -5.0146 - 2.307 0.577 - 161.8 1 2 1 -0.009 14 0 0 0 3.99E+07 2.59E+07 - - - 7.192 0.9998 221125_WJC_METTL3_EV_vs_WT_F06.18306.18306.4 2.81E-08 19/108 K.FK[136.11]DDVMPATYC[160.03]EIDLDK[136.11]EK[136.11].R "sp|Q9HD45|TM9S3_HUMAN,tr|Q5TB53|Q5TB53_HUMAN" 2 2340.108 1.57 86411 18306 4 2340.10735 586.0343 Transmembrane 9 superfamily member 3 OS=Homo sapiens OX=9606 GN=TM9SF3 PE=1 SV=2 4.23 2957.8 - 1.60E+06 - - - -0.2718 - 3.238 0.46 - 177.1 1 2 2 -0.0006 19 0 0 0 4.74E+07 3.01E+07 - - - 3.6271 1 221125_WJC_METTL3_EV_vs_WT_F06.18308.18308.3 3.40E-07 15/88 K.ASVPPDLPPPPQPAPVDEEPQAR.F sp|Q96T58|MINT_HUMAN 1 2403.207 4.64 86413 18308 3 2403.207236 802.0763 Msx2-interacting protein OS=Homo sapiens OX=9606 GN=SPEN PE=1 SV=1 3.92 2958.1 - 400900 - - - 0.0816 - 2.765 0.542 - 146.6 1 2 0 0.0002 23 0 0 0 4.45E+06 9.58E+05 - - - 6.9686 0.9999 221125_WJC_METTL3_EV_vs_WT_F06.18313.18313.3 6.46E-09 14/80 K.QAVSELDEEQHLEDEELQPPR.S sp|Q9NQS7|INCE_HUMAN 1 2490.151 14.68 86416 18313 3 2490.159333 831.0576 Inner centromere protein OS=Homo sapiens OX=9606 GN=INCENP PE=1 SV=3 3.94 2958.7 - 408522 - - - 3.3299 - 3.171 0.621 - 203.2 1 2 0 0.0083 21 0 0 0 1.08E+07 7.36E+05 - - - 8.228 0.9999 221125_WJC_METTL3_EV_vs_WT_F06.18315.18315.3 4.86E-07 16/60 R.NYGILADATEQVGQHK.D "sp|Q9BZZ5|API5_HUMAN,tr|E9PQK6|E9PQK6_HUMAN,tr|G3V1C3|G3V1C3_HUMAN" 3 1742.8588 2.13 86418 18315 3 1742.861345 581.9602 Apoptosis inhibitor 5 OS=Homo sapiens OX=9606 GN=API5 PE=1 SV=3 5.32 2958.8 - 5.13E+06 - - - 1.4815 - 2.513 0.407 - 288 1 2 0 0.0026 16 0 0 0 1.17E+08 5.50E+07 - - - 5.4413 0.9999 221125_WJC_METTL3_EV_vs_WT_F06.18316.18316.3 1.73E-10 18/60 K.DGENVSMK[136.11]DPPDLLDR[166.11].Q sp|Q96SI9|STRBP_HUMAN 1 1817.8584 1.45 86419 18316 3 1817.859986 606.9601 Spermatid perinuclear RNA-binding protein OS=Homo sapiens OX=9606 GN=STRBP PE=1 SV=1 4.04 2958.9 - 536169 - - - 0.8461 - 3.071 0.585 - 418.6 1 2 1 0.0015 16 0 0 0 1.40E+07 9.67E+06 - - - 7.9407 0.999 221125_WJC_METTL3_EV_vs_WT_F06.18317.18317.4 0.0061 14/78 R.KAVLWQDSFSPHLK.H "sp|Q14671|PUM1_HUMAN,tr|Q5T1Z8|Q5T1Z8_HUMAN,tr|E9PM68|E9PM68_HUMAN,tr|E9PMX1|E9PMX1_HUMAN,tr|H0YEH2|H0YEH2_HUMAN,tr|Q5T1Z4|Q5T1Z4_HUMAN,tr|E9PL65|E9PL65_HUMAN,tr|E9PR38|E9PR38_HUMAN" 8 1654.8831 2.4 86420 18317 4 1654.883492 414.7281 Pumilio homolog 1 OS=Homo sapiens OX=9606 GN=PUM1 PE=1 SV=3 8.6 2959.1 - 497753 - - - 0.2206 - 1.796 0.301 - 128.7 1 2 0 0.0004 14 0 0 0 1.31E+07 5.48E+06 - - - 2.0589 0.9967 221125_WJC_METTL3_EV_vs_WT_F06.18321.18321.4 0.00562 17/96 K.YAINPHLTEDQRFPQLR.L sp|Q9ULX3|NOB1_HUMAN 1 2097.0756 0.79 86422 18321 4 2097.077275 525.2762 RNA-binding protein NOB1 OS=Homo sapiens OX=9606 GN=NOB1 PE=1 SV=1 6.75 2959.6 - 1.40E+06 - - - 0.8121 - 2.494 0.297 - 202 1 2 1 0.0017 17 0 0 0 1.83E+07 2.31E+07 - - - 2.1279 0.9999 221125_WJC_METTL3_EV_vs_WT_F06.18323.18323.3 0.000233 14/52 R.KGVEGLIDIENPNR.V sp|Q13442|HAP28_HUMAN 1 1552.8209 0.64 86424 18323 3 1552.822503 518.6142 28 kDa heat- and acid-stable phosphoprotein OS=Homo sapiens OX=9606 GN=PDAP1 PE=1 SV=1 4.68 2959.8 - 562019 - - - 1.0194 - 2.604 0.401 - 247.2 1 2 0 0.0016 14 0 0 0 9.49E+06 1.48E+07 - - - 5.5537 0.9998 221125_WJC_METTL3_EV_vs_WT_F06.18327.18327.4 7.17E-06 16/102 R.LSLNNGSITHLVIR[166.11]PNGR[166.11].V "sp|Q96HS1|PGAM5_HUMAN,tr|F5GXG4|F5GXG4_HUMAN" 2 1980.1132 0.74 86426 18327 4 1980.106031 496.0356 "Serine\threonine-protein phosphatase PGAM5, mitochondrial OS=Homo sapiens OX=9606 GN=PGAM5 PE=1 SV=2" 12 2960.4 - 2.58E+06 - - - -3.6114 - 3.094 0.472 - 233.5 1 2 0 -0.0072 18 0 0 0 3.67E+07 4.93E+07 - - - 3.7192 1 221125_WJC_METTL3_EV_vs_WT_F06.18329.18329.2 9.52E-14 16/32 R.TYADYESVNEC[160.03]MEGVC[160.03]K.M "sp|P84090|ERH_HUMAN,tr|G3V279|G3V279_HUMAN" 2 2053.8067 3.36 86428 18329 2 2053.810279 1027.9106 Enhancer of rudimentary homolog OS=Homo sapiens OX=9606 GN=ERH PE=1 SV=1 4 2960.6 - 514653 - - - 1.7285 - 3.411 0.718 - 646.7 1 2 0 0.0036 17 0 0 0 8.69E+06 2.59E+06 - - - 7.3597 0.9999 221125_WJC_METTL3_EV_vs_WT_F06.18333.18333.4 9.98E-08 17/126 K.AHGPGLEGGLVGK[136.11]PAEFTIDTK[136.11].G "sp|O75369|FLNB_HUMAN,tr|E7EN95|E7EN95_HUMAN,tr|A0A804HK76|A0A804HK76_HUMAN,tr|A0A804HL72|A0A804HL72_HUMAN" 4 2209.1714 0.5 86430 18333 4 2209.175079 553.3001 Filamin-B OS=Homo sapiens OX=9606 GN=FLNB PE=1 SV=2 5.45 2961.1 - 1.41E+06 - - - 1.673 - 3.119 0.47 - 196.7 1 2 0 0.0037 22 0 0 0 1.19E+07 2.36E+07 - - - 3.6881 0.9999 221125_WJC_METTL3_EV_vs_WT_F06.18334.18334.4 7.48E-11 20/126 K.AHGPGLEGGLVGKPAEFTIDTK.G "sp|O75369|FLNB_HUMAN,tr|E7EN95|E7EN95_HUMAN,tr|A0A804HK76|A0A804HK76_HUMAN,tr|A0A804HL72|A0A804HL72_HUMAN" 4 2193.143 0.48 86431 18334 4 2193.153079 549.293 Filamin-B OS=Homo sapiens OX=9606 GN=FLNB PE=1 SV=2 5.45 2961.2 - 1.42E+06 - - - 4.6034 - 4.062 0.602 - 278 1 2 0 0.0101 22 0 0 0 1.13E+07 2.34E+07 - - - 4.9216 0.9991 221125_WJC_METTL3_EV_vs_WT_F06.18337.18337.2 0.00596 16-Oct R.VLDELTLTK.A "sp|P13645|K1C10_HUMAN,tr|A0A1B0GVI3|A0A1B0GVI3_HUMAN" 2 1030.591 999 86434 18337 2 1030.593492 516.3028 "Keratin, type I cytoskeletal 10 OS=Homo sapiens OX=9606 GN=KRT10 PE=1 SV=6" 4.37 2961.6 - 553586 - - - 2.3918 - 1.762 0.399 - 266.4 1 2 0 0.0025 9 0 0 0 1.72E+07 0.00E+00 - - - 3.626 1 221125_WJC_METTL3_EV_vs_WT_F06.18338.18338.3 4.38E-06 13/64 R.TYADYESVNEC[160.03]MEGVC[160.03]K.M "sp|P84090|ERH_HUMAN,tr|G3V279|G3V279_HUMAN" 2 2053.8067 2.29 86435 18338 3 2053.806437 685.6095 Enhancer of rudimentary homolog OS=Homo sapiens OX=9606 GN=ERH PE=1 SV=1 4 2961.7 - 549127 - - - -0.1422 - 2.409 0.647 - 201.1 1 2 0 -0.0003 17 0 0 0 5.25E+06 2.29E+06 - - - 7.9745 1 221125_WJC_METTL3_EV_vs_WT_F06.18339.18339.2 5.32E-14 18/38 R.FSSC[160.03]GGGGGSFGAGGGFGSR.S sp|P04264|K2C1_HUMAN 1 1764.7274 999 86436 18339 2 1764.724166 883.371 "Keratin, type II cytoskeletal 1 OS=Homo sapiens OX=9606 GN=KRT1 PE=1 SV=6" 8.25 2961.9 - 511066 - - - -1.8501 - 3.968 0.805 - 1124.3 1 2 0 -0.0033 20 0 0 0 1.52E+07 0.00E+00 - - - 8.3742 1 221125_WJC_METTL3_EV_vs_WT_F06.18341.18341.2 3.04E-09 15/30 R.NYGILADATEQVGQHK.D "sp|Q9BZZ5|API5_HUMAN,tr|E9PQK6|E9PQK6_HUMAN,tr|G3V1C3|G3V1C3_HUMAN" 3 1742.8588 8.49 86438 18341 2 1742.861796 872.4367 Apoptosis inhibitor 5 OS=Homo sapiens OX=9606 GN=API5 PE=1 SV=3 5.32 2962.1 - 450948 - - - 1.7402 - 3.185 0.671 - 499.7 1 2 0 0.003 16 0 0 0 5.79E+06 6.82E+05 - - - 6.8442 1 221125_WJC_METTL3_EV_vs_WT_F06.18342.18342.3 4.87E-09 14/84 K.AHGPGLEGGLVGK[136.11]PAEFTIDTK[136.11].G "sp|O75369|FLNB_HUMAN,tr|E7EN95|E7EN95_HUMAN,tr|A0A804HK76|A0A804HK76_HUMAN,tr|A0A804HL72|A0A804HL72_HUMAN" 4 2209.1714 1.11 86439 18342 3 2209.174687 737.3977 Filamin-B OS=Homo sapiens OX=9606 GN=FLNB PE=1 SV=2 5.45 2962.3 - 376206 - - - 1.4956 - 3.12 0.583 - 166.8 1 2 0 0.0033 22 0 0 0 4.21E+06 3.80E+06 - - - 7.7366 0.9999 221125_WJC_METTL3_EV_vs_WT_F06.18343.18343.4 4.16E-05 15/72 R.ALEHFTDLYDIK[136.11]R[166.11].A "sp|Q00610|CLH1_HUMAN,tr|A0A087WVQ6|A0A087WVQ6_HUMAN" 2 1637.8532 0.6 86440 18343 4 1637.851761 410.4706 Clathrin heavy chain 1 OS=Homo sapiens OX=9606 GN=CLTC PE=1 SV=5 5.38 2962.4 - 247206 - - - -0.8951 - 2.829 0.463 - 223.1 1 2 0 -0.0015 13 0 0 0 3.74E+06 6.19E+06 - - - 3.6411 0.9998 221125_WJC_METTL3_EV_vs_WT_F06.18345.18345.3 2.07E-06 19/76 R.TDGSISGDRQPVTVADYISR.A sp|P51116|FXR2_HUMAN 1 2136.0447 0.38 86441 18345 3 2136.050295 713.0222 Fragile X mental retardation syndrome-related protein 2 OS=Homo sapiens OX=9606 GN=FXR2 PE=1 SV=2 4.43 2962.6 - 570803 - - - 2.6076 - 3.351 0.533 - 413.1 1 2 1 0.0056 20 0 0 0 1.74E+07 4.59E+07 - - - 7.4146 0.9997 221125_WJC_METTL3_EV_vs_WT_F06.18348.18348.4 0.0632 Dec-84 K.VYNENLVHMIEHAQK.E sp|O75934|SPF27_HUMAN 1 1823.8989 1.47 86443 18348 4 1823.900228 456.982 Pre-mRNA-splicing factor SPF27 OS=Homo sapiens OX=9606 GN=BCAS2 PE=1 SV=1 6 2962.9 - 538731 - - - 0.7539 - 2.294 0.362 - 65.6 1 2 0 0.0014 15 0 0 0 7.96E+07 5.42E+07 - - - 2.6736 0.9999 221125_WJC_METTL3_EV_vs_WT_F06.18349.18349.3 6.80E-07 16/60 R.NYGILADATEQVGQHK[136.11].D "sp|Q9BZZ5|API5_HUMAN,tr|E9PQK6|E9PQK6_HUMAN,tr|G3V1C3|G3V1C3_HUMAN" 3 1750.873 2.13 86444 18349 3 1750.874514 584.6316 Apoptosis inhibitor 5 OS=Homo sapiens OX=9606 GN=API5 PE=1 SV=3 5.32 2963 - 3.11E+06 - - - 0.8858 - 2.926 0.414 - 304.5 1 2 0 0.0016 16 0 0 0 1.17E+08 5.50E+07 - - - 5.9101 1 221125_WJC_METTL3_EV_vs_WT_F06.18350.18350.3 2.24E-09 16/52 K.K[136.11]VIQYLAYVASSHK[136.11].S "sp|P35579|MYH9_HUMAN,tr|Q5BKV1|Q5BKV1_HUMAN" 2 1621.9163 0.83 86445 18350 3 1621.91174 541.646 Myosin-9 OS=Homo sapiens OX=9606 GN=MYH9 PE=1 SV=4 9.53 2963.1 - 931165 - - - -2.7979 - 3.15 0.551 - 308.2 1 2 0 -0.0045 14 0 0 0 1.52E+07 1.83E+07 - - - 7.7311 0.9688 221125_WJC_METTL3_EV_vs_WT_F06.18351.18351.3 0.00145 13/68 W.DLSSNQAIQIAQHDAPVK[136.11].T "sp|P78406|RAE1L_HUMAN,tr|B0QZ36|B0QZ36_HUMAN,tr|E9PQ57|E9PQ57_HUMAN,tr|E9PPG9|E9PPG9_HUMAN" 4 1942 2.24 86446 18351 3 1942.002503 648.3406 mRNA export factor OS=Homo sapiens OX=9606 GN=RAE1 PE=1 SV=1 5.21 2963.2 - 1.87E+06 - - - 1.3126 - 1.965 0.377 - 126.1 1 1 0 0.0025 18 0 0 0 2.37E+07 1.06E+07 - - - 4.4245 0.9956 221125_WJC_METTL3_EV_vs_WT_F06.18352.18352.3 0.00174 14/88 R.SLFSPQNTLAAPTGHPPTSGVEK[136.11].V sp|Q5VT52|RPRD2_HUMAN 1 2343.195 2.86 86447 18352 3 2343.205464 782.0723 Regulation of nuclear pre-mRNA domain-containing protein 2 OS=Homo sapiens OX=9606 GN=RPRD2 PE=1 SV=1 6.47 2963.3 - 945920 - - - 4.455 - 1.944 0.351 - 128.1 1 2 0 0.0104 23 0 0 0 1.86E+07 6.51E+06 - - - 4.0099 1 221125_WJC_METTL3_EV_vs_WT_F06.18355.18355.3 3.26E-06 15/68 R.GHVTQDAPIPGSPLYTIK.A sp|Q15029|U5S1_HUMAN 1 1892.9996 1.31 86448 18355 3 1893.000066 632.0071 116 kDa U5 small nuclear ribonucleoprotein component OS=Homo sapiens OX=9606 GN=EFTUD2 PE=1 SV=1 6.74 2963.7 - 1.06E+06 - - - 0.2393 - 2.98 0.482 - 263.9 1 2 0 0.0005 18 0 0 0 1.44E+07 1.10E+07 - - - 6.6327 0.9999 221125_WJC_METTL3_EV_vs_WT_F06.18360.18360.3 0.00125 16/48 R.ALEHFTDLYDIK[136.11]R[166.11].A "sp|Q00610|CLH1_HUMAN,tr|A0A087WVQ6|A0A087WVQ6_HUMAN" 2 1637.8532 0.95 86453 18360 3 1637.857918 546.9584 Clathrin heavy chain 1 OS=Homo sapiens OX=9606 GN=CLTC PE=1 SV=5 5.38 2964.3 - 418266 - - - 2.8641 - 2.875 0.453 - 268.8 1 2 0 0.0047 13 0 0 0 3.82E+06 4.04E+06 - - - 6.4525 0.9999 221125_WJC_METTL3_EV_vs_WT_F06.18361.18361.3 4.04E-07 14/52 R.SDSFENPVLQQHFR.N "sp|P12956|XRCC6_HUMAN,tr|B1AHC9|B1AHC9_HUMAN" 2 1702.8063 1.03 86454 18361 3 1702.810518 568.6094 X-ray repair cross-complementing protein 6 OS=Homo sapiens OX=9606 GN=XRCC6 PE=1 SV=2 5.3 2964.4 - 413186 - - - 2.4577 - 2.189 0.559 - 211.3 1 2 0 0.0042 14 0 0 0 1.27E+07 1.24E+07 - - - 6.8532 1 221125_WJC_METTL3_EV_vs_WT_F06.18365.18365.3 9.03E-13 28/88 R.GNFGGSFAGSFGGAGGHAPGVAR.K "sp|P52272|HNRPM_HUMAN,tr|M0R2I7|M0R2I7_HUMAN,tr|M0QY96|M0QY96_HUMAN,tr|A0A087X0X3|A0A087X0X3_HUMAN" 4 2033.9456 2.18 86457 18365 3 2033.949142 678.9891 Heterogeneous nuclear ribonucleoprotein M OS=Homo sapiens OX=9606 GN=HNRNPM PE=1 SV=3 9.76 2964.9 - 923789 - - - 1.7316 - 4.709 0.7 - 1020.7 1 2 0 0.0035 23 0 0 0 3.93E+07 1.80E+07 - - - 9.9783 1 221125_WJC_METTL3_EV_vs_WT_F06.18366.18366.4 1.67E-05 16/72 R.ALEHFTDLYDIKR.A "sp|Q00610|CLH1_HUMAN,tr|A0A087WVQ6|A0A087WVQ6_HUMAN" 2 1619.8308 0.61 86458 18366 4 1619.8322 405.965 Clathrin heavy chain 1 OS=Homo sapiens OX=9606 GN=CLTC PE=1 SV=5 5.38 2965 - 326319 - - - 0.8908 - 2.856 0.52 - 206.1 1 2 0 0.0014 13 0 0 0 3.74E+06 6.11E+06 - - - 4.1408 1 221125_WJC_METTL3_EV_vs_WT_F06.18367.18367.4 1.50E-10 25/120 K.AVAFQNPQTHVIENLHAAAYR.N "sp|P22695|QCR2_HUMAN,tr|H3BP04|H3BP04_HUMAN,tr|H3BRG4|H3BRG4_HUMAN,tr|H3BSJ9|H3BSJ9_HUMAN" 4 2349.1978 1.65 86459 18367 4 2349.203807 588.3067 "Cytochrome b-c1 complex subunit 2, mitochondrial OS=Homo sapiens OX=9606 GN=UQCRC2 PE=1 SV=3" 6.96 2965.1 - 2.06E+06 - - - 2.5519 - 4.545 0.556 - 489.3 1 2 0 0.006 21 0 0 0 1.09E+08 6.64E+07 - - - 4.5644 0.9999 221125_WJC_METTL3_EV_vs_WT_F06.18368.18368.3 9.00E-11 18/52 K.DHLVTAYNHLFETK[136.11].R sp|Q00688|FKBP3_HUMAN 1 1694.8508 0.34 86460 18368 3 1694.856902 565.9575 Peptidyl-prolyl cis-trans isomerase FKBP3 OS=Homo sapiens OX=9606 GN=FKBP3 PE=1 SV=1 5.99 2965.2 - 990069 - - - 3.618 - 3.469 0.594 - 383.6 1 2 0 0.0061 14 0 0 0 1.05E+07 3.06E+07 - - - 8.4664 1 221125_WJC_METTL3_EV_vs_WT_F06.18372.18372.3 7.88E-09 14/52 R.SDSFENPVLQQHFR[166.11].N "sp|P12956|XRCC6_HUMAN,tr|B1AHC9|B1AHC9_HUMAN" 2 1712.8146 0.85 86464 18372 3 1712.815565 571.9455 X-ray repair cross-complementing protein 6 OS=Homo sapiens OX=9606 GN=XRCC6 PE=1 SV=2 5.3 2965.7 - 470041 - - - 0.5616 - 3.047 0.555 - 281.3 1 2 0 0.001 14 0 0 0 3.80E+06 4.46E+06 - - - 7.6883 1 221125_WJC_METTL3_EV_vs_WT_F06.18380.18380.3 4.98E-10 18/52 K.HWPFMVVNDAGRPK.V "sp|P11142|HSP7C_HUMAN,tr|E9PQQ4|E9PQQ4_HUMAN,tr|E9PNE6|E9PNE6_HUMAN,tr|E9PKE3|E9PKE3_HUMAN,tr|E9PN89|E9PN89_HUMAN,tr|E9PLF4|E9PLF4_HUMAN,tr|E9PK54|E9PK54_HUMAN,tr|E9PN25|E9PN25_HUMAN,tr|E9PPY6|E9PPY6_HUMAN,tr|E9PQK7|E9PQK7_HUMAN" 10 1652.8246 0.1 86470 18380 3 1652.825756 551.9488 Heat shock cognate 71 kDa protein OS=Homo sapiens OX=9606 GN=HSPA8 PE=1 SV=1 8.75 2966.7 - 1.30E+06 - - - 0.72 - 3.488 0.612 - 562.7 1 2 0 0.0012 14 0 0 0 1.57E+08 1.55E+09 - - - 8.683 1 221125_WJC_METTL3_EV_vs_WT_F06.18381.18381.2 9.75E-09 16/28 K.NQVALNPQNTVFDAK[136.11].R "sp|P0DMV8|HS71A_HUMAN,sp|P0DMV9|HS71B_HUMAN,tr|A0A0G2JIW1|A0A0G2JIW1_HUMAN" 3 1665.8566 0.16 86471 18381 2 1665.858021 833.9356 Heat shock 70 kDa protein 1A OS=Homo sapiens OX=9606 GN=HSPA1A PE=1 SV=1 5.84 2966.8 - 1.84E+06 - - - 0.8626 - 3.147 0.646 - 661.4 1 2 0 0.0014 15 0 0 0 3.97E+07 2.41E+08 - - - 6.6305 0.9999 221125_WJC_METTL3_EV_vs_WT_F06.18382.18382.4 0.00034 14/126 K.AQEVEAELLESHQEETNQLLKK.L "sp|Q13439|GOGA4_HUMAN,tr|H0Y6I0|H0Y6I0_HUMAN" 2 2565.2922 2.09 86472 18382 4 2565.296812 642.3303 Golgin subfamily A member 4 OS=Homo sapiens OX=9606 GN=GOLGA4 PE=1 SV=1 4.47 2966.9 - 741436 - - - 1.7877 - 3.305 0.426 - 114.6 1 2 0 0.0046 22 0 0 0 1.02E+07 4.90E+06 - - - 3.3238 0.9998 221125_WJC_METTL3_EV_vs_WT_F06.18384.18384.4 0.00511 11/102 R.TGMVIHQVEAKPSVYFIK.F "sp|Q5JUX0|SPIN3_HUMAN,sp|Q9Y657|SPIN1_HUMAN,tr|A0A1W2PR54|A0A1W2PR54_HUMAN" 3 2046.0972 6.04 86474 18384 4 2046.096914 512.5316 Spindlin-3 OS=Homo sapiens OX=9606 GN=SPIN3 PE=1 SV=1 8.2 2967.2 - 506688 - - - -0.1491 - 2.292 0.381 - 78.6 1 2 0 -0.0003 18 0 0 0 9.97E+06 1.65E+06 - - - 2.8263 1 221125_WJC_METTL3_EV_vs_WT_F06.18385.18385.3 6.19E-13 22/84 R.ESSLDGLGGTGK[136.11]DNLTSATLPR[166.11].N sp|Q8WUF5|IASPP_HUMAN 1 2206.1196 0.46 86475 18385 3 2206.125 736.3805 RelA-associated inhibitor OS=Homo sapiens OX=9606 GN=PPP1R13L PE=1 SV=4 4.56 2967.3 - 470452 - - - 2.4364 - 4.082 0.626 - 691.1 1 2 1 0.0054 22 0 0 0 3.25E+07 7.00E+07 - - - 8.8526 0.9997 221125_WJC_METTL3_EV_vs_WT_F06.18387.18387.3 0.00058 Nov-60 K.DIETTTISNFHTQVNR.T "sp|Q5VWQ0|RSBN1_HUMAN,tr|A0A087WWP8|A0A087WWP8_HUMAN,tr|A0A0C4DGT8|A0A0C4DGT8_HUMAN" 3 1874.9123 0.61 86477 18387 3 1874.918169 625.978 Lysine-specific demethylase 9 OS=Homo sapiens OX=9606 GN=RSBN1 PE=1 SV=2 5.32 2967.6 - 390147 - - - 3.1543 - 2.415 0.441 - 63 1 2 0 0.0059 16 0 0 0 4.85E+06 7.93E+06 - - - 5.7174 0.9997 221125_WJC_METTL3_EV_vs_WT_F06.18388.18388.4 0.0263 13/90 K.EGVIGVTEEQVHHIVK[136.11].Q sp|Q9UH99|SUN2_HUMAN 1 1780.9563 3.26 86478 18388 4 1780.954684 446.2464 SUN domain-containing protein 2 OS=Homo sapiens OX=9606 GN=SUN2 PE=1 SV=3 5.33 2967.7 - 354121 - - - -0.9063 - 2.634 0.342 - 93.5 1 2 0 -0.0016 16 0 0 0 1.95E+07 6.00E+06 - - - 2.5435 0.9999 221125_WJC_METTL3_EV_vs_WT_F06.18389.18389.4 4.83E-05 Dec-84 K.HFC[160.03]PNVPIILVGNKK.D "sp|P61586|RHOA_HUMAN,sp|P08134|RHOC_HUMAN,tr|E9PQH6|E9PQH6_HUMAN,tr|C9JNR4|C9JNR4_HUMAN,tr|A0A7I2V3G1|A0A7I2V3G1_HUMAN,tr|Q5JR08|Q5JR08_HUMAN,tr|C9JX21|C9JX21_HUMAN,tr|Q5JR05|Q5JR05_HUMAN,tr|Q5JR07|Q5JR07_HUMAN" 9 1734.9603 1.24 86479 18389 4 1734.96405 434.7474 Transforming protein RhoA OS=Homo sapiens OX=9606 GN=RHOA PE=1 SV=1 9.31 2967.8 - 210070 - - - 2.1436 - 2.252 0.467 - 113.5 1 2 0 0.0037 15 0 0 0 3.69E+07 2.98E+07 - - - 3.5802 0.9994 221125_WJC_METTL3_EV_vs_WT_F06.18394.18394.4 0.00348 13/84 K.VYNENLVHMIEHAQK[136.11].E sp|O75934|SPF27_HUMAN 1 1831.9131 1.47 86483 18394 4 1831.914115 458.9855 Pre-mRNA-splicing factor SPF27 OS=Homo sapiens OX=9606 GN=BCAS2 PE=1 SV=1 6 2968.2 - 1.98E+06 - - - 0.5797 - 1.982 0.321 - 73.8 1 2 0 0.0011 15 0 0 0 7.92E+07 5.41E+07 - - - 2.2645 1 221125_WJC_METTL3_EV_vs_WT_F06.18395.18395.3 3.60E-14 22/68 R.HAIYDK[136.11]LDDDGLIAPGVR[166.11].V "sp|P30876|RPB2_HUMAN,tr|C9J4M6|C9J4M6_HUMAN,tr|C9J2Y9|C9J2Y9_HUMAN" 3 1985.0337 1.69 86484 18395 3 1985.045 662.6852 DNA-directed RNA polymerase II subunit RPB2 OS=Homo sapiens OX=9606 GN=POLR2B PE=1 SV=1 4.56 2968.3 - 1.10E+06 - - - 5.6876 - 3.708 0.647 - 725 1 2 1 0.0113 18 0 0 0 1.13E+07 6.68E+06 - - - 9.0135 0.9914 221125_WJC_METTL3_EV_vs_WT_F06.18396.18396.4 0.0536 13/102 R.HAIYDKLDDDGLIAPGVR.V "sp|P30876|RPB2_HUMAN,tr|C9J4M6|C9J4M6_HUMAN,tr|C9J2Y9|C9J2Y9_HUMAN" 3 1967.0112 0.96 86485 18396 4 1967.011621 492.7601 DNA-directed RNA polymerase II subunit RPB2 OS=Homo sapiens OX=9606 GN=POLR2B PE=1 SV=1 4.56 2968.3 - 1.04E+06 - - - 0.1937 - 1.948 0.262 - 122.7 1 2 1 0.0004 18 0 0 0 7.74E+06 8.09E+06 - - - 1.7348 1 221125_WJC_METTL3_EV_vs_WT_F06.18397.18397.4 1.30E-07 18/84 K.C[160.03]FVEHILC[160.03]TKPLPC[160.03]R.Q "sp|Q99567|NUP88_HUMAN,tr|J3KMX1|J3KMX1_HUMAN" 2 1928.9423 1.51 86486 18397 4 1928.940753 483.2429 Nuclear pore complex protein Nup88 OS=Homo sapiens OX=9606 GN=NUP88 PE=1 SV=2 7.97 2968.5 - 755851 - - - -0.8103 - 2.435 0.518 - 220.9 1 2 0 -0.0016 15 0 0 0 2.13E+07 1.41E+07 - - - 4.0527 1 221125_WJC_METTL3_EV_vs_WT_F06.18398.18398.2 1.40E-09 19/28 K.VIEHIMEDLDTNADK.Q sp|P06702|S10A9_HUMAN 1 1741.8193 999 86487 18398 2 1741.820747 871.9169 Protein S100-A9 OS=Homo sapiens OX=9606 GN=S100A9 PE=1 SV=1 4.1 2968.6 - 699822 - - - 0.8503 - 3.703 0.617 - 1484.6 1 2 0 0.0015 15 0 0 0 9.72E+06 0.00E+00 - - - 6.8163 1 221125_WJC_METTL3_EV_vs_WT_F06.18400.18400.4 4.24E-10 15/84 K.HFC[160.03]PNVPIILVGNK[136.11]K[136.11].D "sp|P61586|RHOA_HUMAN,sp|P08134|RHOC_HUMAN,tr|E9PQH6|E9PQH6_HUMAN,tr|C9JNR4|C9JNR4_HUMAN,tr|A0A7I2V3G1|A0A7I2V3G1_HUMAN,tr|Q5JR08|Q5JR08_HUMAN,tr|C9JX21|C9JX21_HUMAN,tr|Q5JR05|Q5JR05_HUMAN,tr|Q5JR07|Q5JR07_HUMAN" 9 1750.9887 1.24 86489 18400 4 1750.988323 438.7545 Transforming protein RhoA OS=Homo sapiens OX=9606 GN=RHOA PE=1 SV=1 9.31 2968.8 - 544771 - - - -0.233 - 2.447 0.597 - 210.9 1 2 0 -0.0004 15 0 0 0 3.71E+07 2.99E+07 - - - 4.7424 0.9999 221125_WJC_METTL3_EV_vs_WT_F06.18401.18401.4 5.11E-07 15/78 K.HWPFMVVNDAGRPK.V "sp|P11142|HSP7C_HUMAN,tr|E9PQQ4|E9PQQ4_HUMAN,tr|E9PNE6|E9PNE6_HUMAN,tr|E9PKE3|E9PKE3_HUMAN,tr|E9PN89|E9PN89_HUMAN,tr|E9PLF4|E9PLF4_HUMAN,tr|E9PK54|E9PK54_HUMAN,tr|E9PN25|E9PN25_HUMAN,tr|E9PPY6|E9PPY6_HUMAN,tr|E9PQK7|E9PQK7_HUMAN" 10 1652.8246 0.12 86490 18401 4 1652.823599 414.2134 Heat shock cognate 71 kDa protein OS=Homo sapiens OX=9606 GN=HSPA8 PE=1 SV=1 8.75 2969 - 514429 - - - -0.5851 - 2.999 0.459 - 220.3 1 2 0 -0.001 14 0 0 0 7.02E+06 5.80E+07 - - - 3.6206 1 221125_WJC_METTL3_EV_vs_WT_F06.18402.18402.3 4.69E-07 17/88 R.GNFGGSFAGSFGGAGGHAPGVAR[166.11].K "sp|P52272|HNRPM_HUMAN,tr|M0R2I7|M0R2I7_HUMAN,tr|M0QY96|M0QY96_HUMAN,tr|A0A087X0X3|A0A087X0X3_HUMAN" 4 2043.9539 2.89 86491 18402 3 2043.956685 682.3252 Heterogeneous nuclear ribonucleoprotein M OS=Homo sapiens OX=9606 GN=HNRNPM PE=1 SV=3 9.76 2969.1 - 482485 - - - 1.3674 - 3.677 0.532 - 265.7 1 2 0 0.0028 23 0 0 0 1.02E+07 3.54E+06 - - - 7.5251 0.9486 221125_WJC_METTL3_EV_vs_WT_F06.18403.18403.3 0.214 Nov-52 K.DHLVTAYNHLFETK.R sp|Q00688|FKBP3_HUMAN 1 1686.8366 0.27 86492 18403 3 1686.846014 563.2861 Peptidyl-prolyl cis-trans isomerase FKBP3 OS=Homo sapiens OX=9606 GN=FKBP3 PE=1 SV=1 5.99 2969.2 - 293014 - - - 5.5986 - 1.889 0.229 - 121.2 1 2 0 0.0094 14 0 0 0 5.09E+06 1.87E+07 - - - 2.7808 1 221125_WJC_METTL3_EV_vs_WT_F06.18406.18406.3 6.04E-13 23/84 R.ESSLDGLGGTGKDNLTSATLPR.N sp|Q8WUF5|IASPP_HUMAN 1 2188.0972 0.75 86494 18406 3 2188.097815 730.373 RelA-associated inhibitor OS=Homo sapiens OX=9606 GN=PPP1R13L PE=1 SV=4 4.56 2969.5 - 1.70E+06 - - - 0.3016 - 4.148 0.655 - 567.4 1 2 1 0.0007 22 0 0 0 3.20E+07 4.26E+07 - - - 9.2152 1 221125_WJC_METTL3_EV_vs_WT_F06.18407.18407.3 1.26E-07 16/56 K.VYNENLVHMIEHAQK.E sp|O75934|SPF27_HUMAN 1 1823.8989 1.51 86495 18407 3 1823.902875 608.9736 Pre-mRNA-splicing factor SPF27 OS=Homo sapiens OX=9606 GN=BCAS2 PE=1 SV=1 6 2969.6 - 1.80E+06 - - - 2.2052 - 2.72 0.553 - 212 1 2 0 0.004 15 0 0 0 5.10E+07 3.38E+07 - - - 7.3153 1 221125_WJC_METTL3_EV_vs_WT_F06.18412.18412.3 2.94E-07 15/56 K.HFC[160.03]PNVPIILVGNK[136.11]K[136.11].D "sp|P61586|RHOA_HUMAN,sp|P08134|RHOC_HUMAN,tr|E9PQH6|E9PQH6_HUMAN,tr|C9JNR4|C9JNR4_HUMAN,tr|A0A7I2V3G1|A0A7I2V3G1_HUMAN,tr|Q5JR08|Q5JR08_HUMAN,tr|C9JX21|C9JX21_HUMAN,tr|Q5JR05|Q5JR05_HUMAN,tr|Q5JR07|Q5JR07_HUMAN" 9 1750.9887 1.27 86498 18412 3 1750.990812 584.6702 Transforming protein RhoA OS=Homo sapiens OX=9606 GN=RHOA PE=1 SV=1 9.31 2970.2 - 525429 - - - 1.1885 - 2.891 0.523 - 374.5 1 2 0 0.0021 15 0 0 0 3.59E+07 2.83E+07 - - - 7.1405 1 221125_WJC_METTL3_EV_vs_WT_F06.18413.18413.3 1.06E-08 21/68 K.R[166.11]PLDDGVGNQLGALVHQR[166.11].T sp|Q96I24|FUBP3_HUMAN 1 1964.0455 2.95 86499 18413 3 1964.047805 655.6891 Far upstream element-binding protein 3 OS=Homo sapiens OX=9606 GN=FUBP3 PE=1 SV=2 6.75 2970.3 - 1.08E+06 - - - 1.1756 - 4.001 0.583 - 549.3 1 2 0 0.0023 18 0 0 0 3.69E+07 1.25E+07 - - - 8.4919 0.9998 221125_WJC_METTL3_EV_vs_WT_F06.18414.18414.3 3.11E-07 19/72 R.GGR[166.11]PNEIEPPPPEMPPWQK[136.11].R "sp|Q8NCA5|FA98A_HUMAN,sp|Q52LJ0|FA98B_HUMAN" 2 2173.0745 1.2 86500 18414 3 2173.080828 725.3655 Protein FAM98A OS=Homo sapiens OX=9606 GN=FAM98A PE=1 SV=2 4.79 2970.4 - 707989 - - - 2.8987 - 3.494 0.386 - 327.8 1 2 0 0.0063 19 0 0 0 1.40E+07 1.16E+07 - - - 5.9154 1 221125_WJC_METTL3_EV_vs_WT_F06.18416.18416.2 7.17E-12 Nov-40 R.SGYRSGGGFSSGSAGIINYQR.R sp|P04264|K2C1_HUMAN 1 2120.0035 -1 86502 18416 2 2120.992023 1061.009 "Keratin, type II cytoskeletal 1 OS=Homo sapiens OX=9606 GN=KRT1 PE=1 SV=6" 9.98 2970.7 - 171270 - - - 466.27 - 2.861 0.708 - 274 1 2 1 0.9885 21 0 0 0 0.00E+00 0.00E+00 - - - 6.5443 1 221125_WJC_METTL3_EV_vs_WT_F06.18418.18418.4 5.81E-07 23/102 K.RPLDDGVGNQLGALVHQR.T sp|Q96I24|FUBP3_HUMAN 1 1944.029 1.56 86503 18418 4 1944.03219 487.0145 Far upstream element-binding protein 3 OS=Homo sapiens OX=9606 GN=FUBP3 PE=1 SV=2 6.75 2971 - 2.64E+06 - - - 1.6636 - 3.868 0.585 - 365.3 1 2 0 0.0032 18 0 0 0 4.69E+07 3.00E+07 - - - 4.7803 1 221125_WJC_METTL3_EV_vs_WT_F06.18420.18420.3 4.33E-11 23/76 K.EVVVYLDDNQKPPVGEGLNR.K "sp|P52948|NUP98_HUMAN,tr|A0A3B3ITD8|A0A3B3ITD8_HUMAN" 2 2240.1437 2.3 86504 18420 3 2240.147095 747.7218 Nuclear pore complex protein Nup98-Nup96 OS=Homo sapiens OX=9606 GN=NUP98 PE=1 SV=4 4.32 2971.2 - 1.05E+06 - - - 1.5106 - 3.489 0.608 - 416.2 1 2 0 0.0034 20 0 0 0 4.47E+07 1.94E+07 - - - 8.3493 0.9999 221125_WJC_METTL3_EV_vs_WT_F06.18421.18421.2 3.15E-06 28-Sep R.ETNLDSLPLVDTHSK[136.11].R sp|P08670|VIME_HUMAN 1 1675.8508 1.89 86505 18421 2 1675.850738 838.9327 Vimentin OS=Homo sapiens OX=9606 GN=VIM PE=1 SV=4 4.54 2971.3 - 392240 - - - -0.0549 - 2.327 0.569 - 185.5 1 2 0 -0.0001 15 0 0 0 1.55E+08 8.20E+07 - - - 5.32 0.9989 221125_WJC_METTL3_EV_vs_WT_F06.18428.18428.4 0.054 16/108 R.VADPDHDHTGFLTEYVATR[166.11].W sp|P28482|MK01_HUMAN 1 2153.0053 0.69 86510 18428 4 2153.013678 539.2586 Mitogen-activated protein kinase 1 OS=Homo sapiens OX=9606 GN=MAPK1 PE=1 SV=3 4.64 2972.1 - 1.56E+06 - - - 3.8834 - 2.758 0.377 - 141.8 1 2 0 0.0084 19 0 0 0 2.89E+07 4.16E+07 - - - 2.8483 1 221125_WJC_METTL3_EV_vs_WT_F06.18429.18429.3 2.36E-12 24/72 R.VADPDHDHTGFLTEYVATR.W sp|P28482|MK01_HUMAN 1 2142.997 1.35 86511 18429 3 2142.999885 715.3396 Mitogen-activated protein kinase 1 OS=Homo sapiens OX=9606 GN=MAPK1 PE=1 SV=3 4.64 2972.2 - 811094 - - - 1.3243 - 4.36 0.647 - 827.8 1 2 0 0.0028 19 0 0 0 2.73E+07 2.02E+07 - - - 9.3702 1 221125_WJC_METTL3_EV_vs_WT_F06.18430.18430.3 2.18E-13 22/76 R.LVSNHSLHETSSVFVDSLTK.A "sp|P21333|FLNA_HUMAN,tr|A0A7P0NMY4|A0A7P0NMY4_HUMAN,tr|Q60FE5|Q60FE5_HUMAN" 3 2199.1172 0.9 86512 18430 3 2199.121643 734.0463 Filamin-A OS=Homo sapiens OX=9606 GN=FLNA PE=1 SV=4 5.99 2972.3 - 760725 - - - 2.0376 - 4.476 0.693 - 474.7 1 2 0 0.0045 20 0 0 0 9.18E+07 1.02E+08 - - - 9.901 0.9999 221125_WJC_METTL3_EV_vs_WT_F06.18431.18431.3 1.89E-05 16/68 R.VAPEEHPVLLTEAPLNPK.A "sp|P63261|ACTG_HUMAN,sp|P60709|ACTB_HUMAN,tr|A0A804GS07|A0A804GS07_HUMAN,tr|I3L3I0|I3L3I0_HUMAN,tr|G5E9R0|G5E9R0_HUMAN,tr|E7EVS6|E7EVS6_HUMAN,tr|A0A6Q8PFE4|A0A6Q8PFE4_HUMAN,tr|J3KT65|J3KT65_HUMAN,tr|I3L3R2|I3L3R2_HUMAN,tr|K7EM38|K7EM38_HUMAN,tr|A0A6Q8PH58|A0A6Q8PH58_HUMAN,tr|I3L1U9|I3L1U9_HUMAN,tr|A0A2R8Y793|A0A2R8Y793_HUMAN,tr|I3L4N8|I3L4N8_HUMAN,tr|A0A2R8YGF8|A0A2R8YGF8_HUMAN" 15 1953.0571 1.13 86513 18431 3 1953.05989 652.0263 "Actin, cytoplasmic 2 OS=Homo sapiens OX=9606 GN=ACTG1 PE=1 SV=1" 4.75 2972.4 - 390179 - - - 1.4142 - 3.018 0.424 - 327 1 2 0 0.0028 18 0 0 0 8.33E+07 7.38E+07 - - - 6.017 1 221125_WJC_METTL3_EV_vs_WT_F06.18433.18433.2 4.24E-09 16/34 K.DVTVLQNTDGNNNEAWAK.D "sp|P02788|TRFL_HUMAN,tr|E7EQB2|E7EQB2_HUMAN,tr|E7ER44|E7ER44_HUMAN" 3 1987.9235 999 86515 18433 2 1987.92478 994.9691 Lactotransferrin OS=Homo sapiens OX=9606 GN=LTF PE=1 SV=6 4.03 2972.7 - 264642 - - - 0.6197 - 3.345 0.692 - 618.1 1 2 0 0.0012 18 0 0 0 7.17E+06 0.00E+00 - - - 7.1203 0.9999 221125_WJC_METTL3_EV_vs_WT_F06.18439.18439.4 5.99E-08 16/108 R.VADPDHDHTGFLTEYVATR.W sp|P28482|MK01_HUMAN 1 2142.997 0.69 86519 18439 4 2143.002203 536.7565 Mitogen-activated protein kinase 1 OS=Homo sapiens OX=9606 GN=MAPK1 PE=1 SV=3 4.64 2973.3 - 1.74E+06 - - - 2.406 - 3.084 0.457 - 184.6 1 2 0 0.0052 19 0 0 0 2.89E+07 4.16E+07 - - - 3.5833 0.9951 221125_WJC_METTL3_EV_vs_WT_F06.18440.18440.3 0.00298 Oct-68 K.DVTVLQNTDGNNNEAWAK.D "sp|P02788|TRFL_HUMAN,tr|E7EQB2|E7EQB2_HUMAN,tr|E7ER44|E7ER44_HUMAN" 3 1987.9235 999 86520 18440 3 1987.91257 663.6485 Lactotransferrin OS=Homo sapiens OX=9606 GN=LTF PE=1 SV=6 4.03 2973.4 - 676404 - - - -5.5223 - 1.836 0.401 - 96.2 1 2 0 -0.011 18 0 0 0 1.25E+07 0.00E+00 - - - 4.5207 1 221125_WJC_METTL3_EV_vs_WT_F06.18447.18447.3 0.00109 17/84 K.VPEIEVTVEGPNNNNPQTSAVR.T "sp|P78347|GTF2I_HUMAN,tr|A0A494C1K3|A0A494C1K3_HUMAN" 2 2363.1717 1.79 86525 18447 3 2363.174704 788.7312 General transcription factor II-I OS=Homo sapiens OX=9606 GN=GTF2I PE=1 SV=2 4.25 2974.3 - 2.01E+06 - - - 1.264 - 3.517 0.49 - 275.3 1 2 0 0.003 22 0 0 0 4.55E+09 2.54E+09 - - - 6.9838 1 221125_WJC_METTL3_EV_vs_WT_F06.18449.18449.2 2.84E-08 24/42 Y.GGGSGGGFSASSLGGGFGGGSR.G sp|P35527|K1C9_HUMAN 1 1771.7874 999 86527 18449 2 1771.785854 886.901 "Keratin, type I cytoskeletal 9 OS=Homo sapiens OX=9606 GN=KRT9 PE=1 SV=3" 9.75 2974.5 - 539554 - - - -0.8658 - 4.209 0.719 - 1509.3 1 1 0 -0.0015 22 0 0 0 7.18E+07 0.00E+00 - - - 7.8845 1 221125_WJC_METTL3_EV_vs_WT_F06.18452.18452.2 1.67E-09 14/34 R.SC[160.03]GSSTPDEFPTDIPGTK[136.11].G "sp|P41091|IF2G_HUMAN,tr|H7BZU1|H7BZU1_HUMAN" 2 1902.8397 1.06 86530 18452 2 1902.840222 952.4271 Eukaryotic translation initiation factor 2 subunit 3 OS=Homo sapiens OX=9606 GN=EIF2S3 PE=1 SV=3 4.03 2974.9 - 322365 - - - 0.2885 - 2.625 0.758 - 395.2 1 2 0 0.0005 18 0 0 0 5.60E+07 5.27E+07 - - - 7.0121 1 221125_WJC_METTL3_EV_vs_WT_F06.18456.18456.3 3.47E-15 18/96 K.LVQDVANNTNEEAGDGTTTATVLAR.S "sp|P10809|CH60_HUMAN,tr|C9JL25|C9JL25_HUMAN,tr|A0A7I2V2X6|A0A7I2V2X6_HUMAN,tr|A0A7I2YQK6|A0A7I2YQK6_HUMAN,tr|A0A7I2V599|A0A7I2V599_HUMAN,tr|E7EXB4|E7EXB4_HUMAN,tr|A0A7I2YQ71|A0A7I2YQ71_HUMAN,tr|E7ESH4|E7ESH4_HUMAN,tr|A0A7I2V5M1|A0A7I2V5M1_HUMAN,tr|A0A7I2V5K3|A0A7I2V5K3_HUMAN,tr|A0A7I2V369|A0A7I2V369_HUMAN" 11 2559.2413 1.48 86533 18456 3 2559.23861 854.0877 "60 kDa heat shock protein, mitochondrial OS=Homo sapiens OX=9606 GN=HSPD1 PE=1 SV=2" 3.92 2975.5 - 1.22E+06 - - - -1.0327 - 3.561 0.718 - 415 1 2 0 -0.0026 25 0 0 0 4.84E+07 3.27E+07 - - - 9.4662 0.9999 221125_WJC_METTL3_EV_vs_WT_F06.18458.18458.3 0.00217 15/56 R.ETNLDSLPLVDTHSK.R sp|P08670|VIME_HUMAN 1 1667.8366 2.71 86534 18458 3 1667.838413 556.9528 Vimentin OS=Homo sapiens OX=9606 GN=VIM PE=1 SV=4 4.54 2975.7 - 4.24E+07 - - - 1.069 - 2.554 0.446 - 312.1 1 2 0 0.0018 15 0 0 0 3.58E+09 1.32E+09 - - - 5.9587 1 221125_WJC_METTL3_EV_vs_WT_F06.18459.18459.3 3.79E-05 Dec-56 R.ETNLDSLPLVDTHSK[136.11].R sp|P08670|VIME_HUMAN 1 1675.8508 2.72 86535 18459 3 1675.850646 559.6242 Vimentin OS=Homo sapiens OX=9606 GN=VIM PE=1 SV=4 4.54 2975.8 - 2.19E+07 - - - -0.1098 - 2.22 0.493 - 209.3 1 2 0 -0.0002 15 0 0 0 3.59E+09 1.32E+09 - - - 6.1174 1 221125_WJC_METTL3_EV_vs_WT_F06.18460.18460.3 6.19E-11 20/72 R.GLLQDDAHPTLVTYADHSK[136.11].L "sp|Q86U44|MTA70_HUMAN,tr|F5H6D8|F5H6D8_HUMAN,tr|H0YFV6|H0YFV6_HUMAN,tr|B4DTN4|B4DTN4_HUMAN" 4 2088.0367 0.74 86536 18460 3 2088.037621 697.0195 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 5.13 2975.9 - 1.66E+06 - - - 0.4253 - 3.581 0.596 - 483.6 1 2 0 0.0009 19 0 0 0 1.13E+08 1.52E+08 - - - 8.3186 1 221125_WJC_METTL3_EV_vs_WT_F06.18461.18461.3 1.69E-07 17/56 K.HFC[160.03]PNVPIILVGNKK.D "sp|P61586|RHOA_HUMAN,sp|P08134|RHOC_HUMAN,tr|E9PQH6|E9PQH6_HUMAN,tr|C9JNR4|C9JNR4_HUMAN,tr|A0A7I2V3G1|A0A7I2V3G1_HUMAN,tr|Q5JR08|Q5JR08_HUMAN,tr|C9JX21|C9JX21_HUMAN,tr|Q5JR05|Q5JR05_HUMAN,tr|Q5JR07|Q5JR07_HUMAN" 9 1734.9603 1.27 86537 18461 3 1734.96146 579.3274 Transforming protein RhoA OS=Homo sapiens OX=9606 GN=RHOA PE=1 SV=1 9.31 2976 - 1.51E+06 - - - 0.6507 - 3.328 0.628 - 553.9 1 2 0 0.0011 15 0 0 0 3.59E+07 2.83E+07 - - - 8.6787 1 221125_WJC_METTL3_EV_vs_WT_F06.18463.18463.3 1.49E-06 17/64 K.VTHAVVTVPAYFNDAQR[166.11].Q "sp|P11021|BIP_HUMAN,tr|A0A7P0TB36|A0A7P0TB36_HUMAN,tr|A0A7P0TAI0|A0A7P0TAI0_HUMAN" 3 1896.9722 0.53 86539 18463 3 1896.972086 633.3313 Endoplasmic reticulum chaperone BiP OS=Homo sapiens OX=9606 GN=HSPA5 PE=1 SV=2 6.71 2976.3 - 827043 - - - -0.0422 - 3.303 0.502 - 554.6 1 2 0 -0.0001 17 0 0 0 3.78E+07 7.18E+07 - - - 7.1553 1 221125_WJC_METTL3_EV_vs_WT_F06.18465.18465.2 3.60E-14 15/34 R.SC[160.03]GSSTPDEFPTDIPGTK.G "sp|P41091|IF2G_HUMAN,tr|H7BZU1|H7BZU1_HUMAN" 2 1894.8255 1.06 86541 18465 2 1894.825331 948.42 Eukaryotic translation initiation factor 2 subunit 3 OS=Homo sapiens OX=9606 GN=EIF2S3 PE=1 SV=3 4.03 2976.5 - 678322 - - - -0.0749 - 2.884 0.758 - 469.5 1 2 0 -0.0001 18 0 0 0 5.60E+07 5.27E+07 - - - 7.2436 0.9969 221125_WJC_METTL3_EV_vs_WT_F06.18466.18466.4 0.462 14/84 K.DAIK[136.11]ENPEFDLHFEK[136.11].L sp|Q9NV70|EXOC1_HUMAN 1 1846.9072 1.72 86542 18466 4 1846.911317 462.7341 Exocyst complex component 1 OS=Homo sapiens OX=9606 GN=EXOC1 PE=1 SV=4 4.5 2976.6 - 420566 - - - 2.2134 - 2.899 0.324 - 108.4 1 2 1 0.0041 15 0 0 0 8.56E+06 4.98E+06 - - - 2.4258 0.9999 221125_WJC_METTL3_EV_vs_WT_F06.18467.18467.4 3.15E-07 16/102 R.HINLPLPAPHAQYAIPNR.H "sp|P42694|HELZ_HUMAN,tr|J3QS41|J3QS41_HUMAN" 2 2021.0959 4.21 86543 18467 4 2021.09381 506.2813 Probable helicase with zinc finger domain OS=Homo sapiens OX=9606 GN=HELZ PE=1 SV=2 8.76 2976.8 - 274467 - - - -1.041 - 2.983 0.44 - 180.7 1 2 0 -0.0021 18 0 0 0 2.09E+07 4.96E+06 - - - 3.4296 1 221125_WJC_METTL3_EV_vs_WT_F06.18471.18471.3 0.00127 19/72 K.KQPEPSPALVPSLTVTTEK.T "sp|P55197|AF10_HUMAN,tr|Q5JT35|Q5JT35_HUMAN" 2 2021.1045 11.22 86545 18471 3 2021.104279 674.7088 Protein AF-10 OS=Homo sapiens OX=9606 GN=MLLT10 PE=1 SV=2 6.14 2977.3 - 1.91E+06 - - - -0.0955 - 3.396 0.418 - 380.6 1 2 0 -0.0002 19 0 0 0 1.03E+08 9.21E+06 - - - 6.2039 0.9999 221125_WJC_METTL3_EV_vs_WT_F06.18473.18473.4 0.00664 17/114 R.LVSNHSLHETSSVFVDSLTK[136.11].A "sp|P21333|FLNA_HUMAN,tr|A0A7P0NMY4|A0A7P0NMY4_HUMAN,tr|Q60FE5|Q60FE5_HUMAN" 3 2207.1314 1.09 86547 18473 4 2207.134052 552.7901 Filamin-A OS=Homo sapiens OX=9606 GN=FLNA PE=1 SV=4 5.99 2977.4 - 2.95E+06 - - - 1.2188 - 2.915 0.394 - 248.9 1 2 0 0.0027 20 0 0 0 7.89E+07 7.25E+07 - - - 3.0123 1 221125_WJC_METTL3_EV_vs_WT_F06.18475.18475.3 8.97E-09 18/76 K.VNNSSLIGVGYTQTLRPGVK.L "sp|P45880|VDAC2_HUMAN,tr|A0A0A0MR02|A0A0A0MR02_HUMAN" 2 2102.1484 1.33 86549 18475 3 2102.142841 701.7234 Voltage-dependent anion-selective channel protein 2 OS=Homo sapiens OX=9606 GN=VDAC2 PE=1 SV=2 9.99 2977.6 - 585482 - - - -2.6459 - 4.135 0.546 - 461.3 1 2 0 -0.0056 20 0 0 0 4.71E+07 3.53E+07 - - - 8.0695 1 221125_WJC_METTL3_EV_vs_WT_F06.18480.18480.2 1.58E-10 21/42 K.VPEIEVTVEGPNNNNPQTSAVR.T "sp|P78347|GTF2I_HUMAN,tr|A0A494C1K3|A0A494C1K3_HUMAN" 2 2363.1717 1.84 86552 18480 2 2363.171156 1182.5931 General transcription factor II-I OS=Homo sapiens OX=9606 GN=GTF2I PE=1 SV=2 4.25 2978.3 - 991845 - - - -0.2374 - 4.524 0.705 - 870.6 1 2 0 -0.0006 22 0 0 0 5.37E+08 2.92E+08 - - - 7.9589 0.9982 221125_WJC_METTL3_EV_vs_WT_F06.18481.18481.3 0.00139 Sep-40 K.TKENILEEFSK.V "sp|O43390|HNRPR_HUMAN,tr|B4DT28|B4DT28_HUMAN,tr|A0A6Q8PHG0|A0A6Q8PHG0_HUMAN,tr|A0A6Q8PH31|A0A6Q8PH31_HUMAN,tr|A0A6Q8PEX7|A0A6Q8PEX7_HUMAN" 5 1336.6874 1.35 86553 18481 3 1336.686794 446.5698 Heterogeneous nuclear ribonucleoprotein R OS=Homo sapiens OX=9606 GN=HNRNPR PE=1 SV=1 4.78 2978.4 - 561958 - - - -0.4885 - 1.895 0.329 - 166.5 1 2 1 -0.0007 11 0 0 0 2.29E+07 1.70E+07 - - - 4.0238 1 221125_WJC_METTL3_EV_vs_WT_F06.18482.18482.4 1.11E-06 20/102 K.VTEGLTDVILYHQPDDKK.K "sp|O60506|HNRPQ_HUMAN,tr|A0A7I2YQV8|A0A7I2YQV8_HUMAN,tr|A0A7I2YQN2|A0A7I2YQN2_HUMAN,tr|A0A7I2V5Q6|A0A7I2V5Q6_HUMAN,tr|A0A7I2V4Z0|A0A7I2V4Z0_HUMAN,tr|B7Z645|B7Z645_HUMAN,tr|A0A7I2V2F2|A0A7I2V2F2_HUMAN,tr|A0A7I2V346|A0A7I2V346_HUMAN,tr|A0A7I2V309|A0A7I2V309_HUMAN" 9 2070.0633 1.11 86554 18482 4 2070.063979 518.5231 Heterogeneous nuclear ribonucleoprotein Q OS=Homo sapiens OX=9606 GN=SYNCRIP PE=1 SV=2 4.66 2978.6 - 376680 - - - 0.3106 - 3.356 0.466 - 248.3 1 2 0 0.0006 18 0 0 0 1.47E+07 1.32E+07 - - - 3.6966 1 221125_WJC_METTL3_EV_vs_WT_F06.18485.18485.3 7.04E-11 23/76 K.VNNSSLIGVGYTQTLR[166.11]PGVK[136.11].L "sp|P45880|VDAC2_HUMAN,tr|A0A0A0MR02|A0A0A0MR02_HUMAN" 2 2120.1709 1.33 86555 18485 3 2120.17094 707.7309 Voltage-dependent anion-selective channel protein 2 OS=Homo sapiens OX=9606 GN=VDAC2 PE=1 SV=2 9.99 2979 - 1.13E+06 - - - 0.0316 - 4.143 0.607 - 694.9 1 2 0 0.0001 20 0 0 0 4.71E+07 3.53E+07 - - - 8.7558 1 221125_WJC_METTL3_EV_vs_WT_F06.18486.18486.2 5.45E-17 21/42 K.VPEIEVTVEGPNNNNPQTSAVR[166.11].T "sp|P78347|GTF2I_HUMAN,tr|A0A494C1K3|A0A494C1K3_HUMAN" 2 2373.18 1.84 86556 18486 2 2373.178836 1187.5973 General transcription factor II-I OS=Homo sapiens OX=9606 GN=GTF2I PE=1 SV=2 4.25 2979.1 - 818654 - - - -0.485 - 4.668 0.724 - 1089.1 1 2 0 -0.0012 22 0 0 0 5.37E+08 2.92E+08 - - - 8.1761 0.9951 221125_WJC_METTL3_EV_vs_WT_F06.18487.18487.3 2.31E-06 23/88 A.AFASSLVSGLNSSASEPAK[136.11]EPAK[136.11].K "sp|Q86U44|MTA70_HUMAN,tr|F5H6D8|F5H6D8_HUMAN,tr|H0YFV6|H0YFV6_HUMAN,tr|B4DTN4|B4DTN4_HUMAN" 4 2263.1667 0 86557 18487 3 2263.166519 755.3962 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 6.19 2979.2 - 2.11E+06 - - - -0.0764 - 3.764 0.594 - 426 1 1 1 -0.0002 23 0 0 0 1.42E+05 1.56E+08 - - - 8.272 0.9949 221125_WJC_METTL3_EV_vs_WT_F06.18489.18489.3 0.103 Nov-40 K.TK[136.11]ENILEEFSK[136.11].V "sp|O43390|HNRPR_HUMAN,tr|B4DT28|B4DT28_HUMAN,tr|A0A6Q8PHG0|A0A6Q8PHG0_HUMAN,tr|A0A6Q8PH31|A0A6Q8PH31_HUMAN,tr|A0A6Q8PEX7|A0A6Q8PEX7_HUMAN" 5 1352.7158 1.35 86559 18489 3 1352.715399 451.9126 Heterogeneous nuclear ribonucleoprotein R OS=Homo sapiens OX=9606 GN=HNRNPR PE=1 SV=1 4.78 2979.4 - 528152 - - - -0.3312 - 1.948 0.251 - 220.2 1 2 1 -0.0004 11 0 0 0 2.29E+07 1.70E+07 - - - 3.2326 0.9995 221125_WJC_METTL3_EV_vs_WT_F06.18493.18493.2 1.53E-05 24-Sep K.DEILPTTPISEQK[136.11].G "sp|P23396|RS3_HUMAN,tr|H0YEU2|H0YEU2_HUMAN,tr|E9PSF4|E9PSF4_HUMAN,tr|E9PL09|E9PL09_HUMAN,tr|E9PPU1|E9PPU1_HUMAN" 5 1477.7755 0.77 86561 18493 2 1477.771734 739.895 40S ribosomal protein S3 OS=Homo sapiens OX=9606 GN=RPS3 PE=1 SV=2 4.14 2979.9 - 520985 - - - -2.5755 - 1.789 0.517 - 171.2 1 2 0 -0.0038 13 0 0 0 7.48E+06 9.74E+06 - - - 4.3512 1 221125_WJC_METTL3_EV_vs_WT_F06.18497.18497.3 8.29E-09 20/84 K.VPEIEVTVEGPNNNNPQTSAVR[166.11].T "sp|P78347|GTF2I_HUMAN,tr|A0A494C1K3|A0A494C1K3_HUMAN" 2 2373.18 1.79 86563 18497 3 2373.177412 792.0673 General transcription factor II-I OS=Homo sapiens OX=9606 GN=GTF2I PE=1 SV=2 4.25 2980.4 - 2.53E+07 - - - -1.085 - 4.13 0.613 - 358.8 1 2 0 -0.0026 22 0 0 0 4.55E+09 2.54E+09 - - - 8.7361 0.8685 221125_WJC_METTL3_EV_vs_WT_F06.18500.18500.2 0.11 14-Sep L.PLVDTHSK.R sp|P08670|VIME_HUMAN 1 895.4763 1.82 86566 18500 2 895.47932 448.7454 Vimentin OS=Homo sapiens OX=9606 GN=VIM PE=1 SV=4 7.17 2980.8 - 572928 - - - 3.3379 - 1.826 0.315 - 218.3 1 1 0 0.003 8 0 0 0 1.87E+07 1.02E+07 - - - 3.1826 1 221125_WJC_METTL3_EV_vs_WT_F06.18502.18502.4 2.03E-08 17/78 K.HWPFMVVNDAGR[166.11]PK[136.11].V "sp|P11142|HSP7C_HUMAN,tr|E9PQQ4|E9PQQ4_HUMAN,tr|E9PNE6|E9PNE6_HUMAN,tr|E9PKE3|E9PKE3_HUMAN,tr|E9PN89|E9PN89_HUMAN,tr|E9PLF4|E9PLF4_HUMAN,tr|E9PK54|E9PK54_HUMAN,tr|E9PN25|E9PN25_HUMAN,tr|E9PPY6|E9PPY6_HUMAN,tr|E9PQK7|E9PQK7_HUMAN" 10 1670.847 0.13 86567 18502 4 1670.845907 418.719 Heat shock cognate 71 kDa protein OS=Homo sapiens OX=9606 GN=HSPA8 PE=1 SV=1 8.75 2981 - 4.10E+06 - - - -0.6757 - 2.984 0.57 - 283.6 1 2 0 -0.0011 14 0 0 0 4.53E+07 3.43E+08 - - - 4.5849 1 221125_WJC_METTL3_EV_vs_WT_F06.18504.18504.3 0.000269 25/72 R.GGRPNEIEPPPPEMPPWQK.R "sp|Q8NCA5|FA98A_HUMAN,sp|Q52LJ0|FA98B_HUMAN" 2 2155.0521 1.01 86568 18504 3 2155.054895 719.358 Protein FAM98A OS=Homo sapiens OX=9606 GN=FAM98A PE=1 SV=2 4.79 2981.2 - 794080 - - - 1.316 - 3.726 0.539 - 866.5 1 2 0 0.0028 19 0 0 0 5.85E+07 5.81E+07 - - - 7.7801 0.9998 221125_WJC_METTL3_EV_vs_WT_F06.18509.18509.4 0.000171 12/114 R.LVSNHSLHETSSVFVDSLTK.A "sp|P21333|FLNA_HUMAN,tr|A0A7P0NMY4|A0A7P0NMY4_HUMAN,tr|Q60FE5|Q60FE5_HUMAN" 3 2199.1172 1.09 86571 18509 4 2199.120138 550.7866 Filamin-A OS=Homo sapiens OX=9606 GN=FLNA PE=1 SV=4 5.99 2981.7 - 3.22E+06 - - - 1.3533 - 2.206 0.399 - 107.5 1 2 0 0.003 20 0 0 0 7.89E+07 7.26E+07 - - - 2.9626 0.9999 221125_WJC_METTL3_EV_vs_WT_F06.18512.18512.3 1.06E-05 14/68 K.NLTVILSDASAPGEGEHK[136.11].L sp|Q9H0D6|XRN2_HUMAN 1 1844.936 0.14 86573 18512 3 1844.930932 615.9859 5'-3' exoribonuclease 2 OS=Homo sapiens OX=9606 GN=XRN2 PE=1 SV=1 4.65 2982 - 1.89E+06 - - - -2.7237 - 2.833 0.503 - 156 1 2 0 -0.005 18 0 0 0 2.70E+07 1.89E+08 - - - 6.7396 1 221125_WJC_METTL3_EV_vs_WT_F06.18513.18513.3 3.56E-09 25/72 R.NNQVLGIGSGSTIVHAVQR.L sp|P49247|RPIA_HUMAN 1 1949.0443 0.73 86574 18513 3 1949.044342 650.6887 Ribose-5-phosphate isomerase OS=Homo sapiens OX=9606 GN=RPIA PE=1 SV=3 9.76 2982.1 - 2.48E+06 - - - 0.0359 - 4.485 0.634 - 1001.3 1 2 0 0.0001 19 0 0 0 7.46E+07 1.02E+08 - - - 9.2955 0.9999 221125_WJC_METTL3_EV_vs_WT_F06.18514.18514.4 0.000537 18/126 K.VPEIEVTVEGPNNNNPQTSAVR.T "sp|P78347|GTF2I_HUMAN,tr|A0A494C1K3|A0A494C1K3_HUMAN" 2 2363.1717 1.42 86575 18514 4 2363.168077 591.8002 General transcription factor II-I OS=Homo sapiens OX=9606 GN=GTF2I PE=1 SV=2 4.25 2982.1 - 1.38E+06 - - - -1.5403 - 2.953 0.434 - 245.5 1 2 0 -0.0036 22 0 0 0 7.22E+07 5.07E+07 - - - 3.3568 1 221125_WJC_METTL3_EV_vs_WT_F06.18515.18515.3 2.17E-08 24/84 K.VTFFEPGSGDENGTSNKEDEFR.M "sp|O95793|STAU1_HUMAN,tr|Q5JW30|Q5JW30_HUMAN" 2 2461.067 2.25 86576 18515 3 2461.069293 821.3629 Double-stranded RNA-binding protein Staufen homolog 1 OS=Homo sapiens OX=9606 GN=STAU1 PE=1 SV=2 4.08 2982.3 - 1.12E+06 - - - 0.9411 - 3.14 0.659 - 308.4 1 2 1 0.0023 22 0 0 0 1.51E+08 6.70E+07 - - - 8.5993 1 221125_WJC_METTL3_EV_vs_WT_F06.18522.18522.4 1.43E-06 19/126 K.VPEIEVTVEGPNNNNPQTSAVR[166.11].T "sp|P78347|GTF2I_HUMAN,tr|A0A494C1K3|A0A494C1K3_HUMAN" 2 2373.18 1.52 86581 18522 4 2373.183563 594.3023 General transcription factor II-I OS=Homo sapiens OX=9606 GN=GTF2I PE=1 SV=2 4.25 2983.1 - 823106 - - - 1.5068 - 3.705 0.496 - 234.9 1 2 0 0.0036 22 0 0 0 8.05E+07 5.30E+07 - - - 3.9707 0.895 221125_WJC_METTL3_EV_vs_WT_F06.18523.18523.2 0.43 Jun-34 R.EAPNPIHLTVDTSLQNGR.M "sp|O00303|EIF3F_HUMAN,tr|H0YDT6|H0YDT6_HUMAN,tr|A0A7I2YQA0|A0A7I2YQA0_HUMAN" 3 1960.9967 3.62 86582 18523 2 1960.987625 981.5056 Eukaryotic translation initiation factor 3 subunit F OS=Homo sapiens OX=9606 GN=EIF3F PE=1 SV=1 5.32 2983.3 - 393312 - - - -4.6038 - 1.163 0.184 - 57.8 1 2 0 -0.009 18 0 0 0 8.24E+06 2.28E+06 - - - 0.7684 0.991 221125_WJC_METTL3_EV_vs_WT_F06.18528.18528.3 0.00239 14/68 L.K[136.11]TELEDTLDSTAAQQELR[166.11].S sp|P35579|MYH9_HUMAN 1 2065.0294 0.53 86585 18528 3 2065.032151 689.3504 Myosin-9 OS=Homo sapiens OX=9606 GN=MYH9 PE=1 SV=4 4.18 2983.9 - 431920 - - - 1.3259 - 2.358 0.442 - 234.7 1 1 0 0.0027 18 0 0 0 5.60E+06 1.06E+07 - - - 5.6031 1 221125_WJC_METTL3_EV_vs_WT_F06.18533.18533.3 2.63E-12 17/80 R.SQVEPADYKADEDPALFQSVK.T "sp|P48739|PIPNB_HUMAN,tr|A0A0A0MSW4|A0A0A0MSW4_HUMAN,tr|B3KYB6|B3KYB6_HUMAN" 3 2336.1172 1.11 86588 18533 3 2336.111698 779.713 Phosphatidylinositol transfer protein beta isoform OS=Homo sapiens OX=9606 GN=PITPNB PE=1 SV=2 4.1 2984.6 - 1.42E+06 - - - -2.3646 - 3.761 0.684 - 195.6 1 2 1 -0.0055 21 0 0 0 7.94E+07 7.13E+07 - - - 9.3403 1 221125_WJC_METTL3_EV_vs_WT_F06.18539.18539.3 2.25E-10 20/96 K.LVQDVANNTNEEAGDGTTTATVLAR[166.11].S "sp|P10809|CH60_HUMAN,tr|C9JL25|C9JL25_HUMAN,tr|A0A7I2V2X6|A0A7I2V2X6_HUMAN,tr|A0A7I2YQK6|A0A7I2YQK6_HUMAN,tr|A0A7I2V599|A0A7I2V599_HUMAN,tr|E7EXB4|E7EXB4_HUMAN,tr|A0A7I2YQ71|A0A7I2YQ71_HUMAN,tr|E7ESH4|E7ESH4_HUMAN,tr|A0A7I2V5M1|A0A7I2V5M1_HUMAN,tr|A0A7I2V5K3|A0A7I2V5K3_HUMAN,tr|A0A7I2V369|A0A7I2V369_HUMAN" 11 2569.2495 1.36 86592 18539 3 2569.24463 857.4238 "60 kDa heat shock protein, mitochondrial OS=Homo sapiens OX=9606 GN=HSPD1 PE=1 SV=2" 3.92 2985.3 - 893892 - - - -1.9044 - 3.916 0.624 - 584.5 1 2 0 -0.0049 25 0 0 0 3.26E+07 2.40E+07 - - - 8.6362 0.9999 221125_WJC_METTL3_EV_vs_WT_F06.18540.18540.3 1.06E-07 19/84 K.VTFFEPGSGDENGTSNK[136.11]EDEFR[166.11].M "sp|O95793|STAU1_HUMAN,tr|Q5JW30|Q5JW30_HUMAN" 2 2479.0894 2.25 86593 18540 3 2479.08336 827.3704 Double-stranded RNA-binding protein Staufen homolog 1 OS=Homo sapiens OX=9606 GN=STAU1 PE=1 SV=2 4.08 2985.4 - 2.03E+06 - - - -2.4553 - 3.326 0.623 - 266.5 1 2 1 -0.0061 22 0 0 0 1.51E+08 6.70E+07 - - - 8.3333 1 221125_WJC_METTL3_EV_vs_WT_F06.18547.18547.4 1.08E-07 14/108 R.GLLQDDAHPTLVTYADHSK[136.11].L "sp|Q86U44|MTA70_HUMAN,tr|F5H6D8|F5H6D8_HUMAN,tr|H0YFV6|H0YFV6_HUMAN,tr|B4DTN4|B4DTN4_HUMAN" 4 2088.0367 0.1 86595 18547 4 2088.033844 523.0165 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 5.13 2986.3 - 4.47E+06 - - - -1.3836 - 2.745 0.588 - 155.6 1 2 0 -0.0029 19 0 0 0 3.02E+07 2.91E+08 - - - 4.6847 0.9999 221125_WJC_METTL3_EV_vs_WT_F06.18556.18556.3 0.000114 Dec-64 K.EIENGHIFTVNDQFTSK.L "sp|Q13618|CUL3_HUMAN,tr|A0A087WTG3|A0A087WTG3_HUMAN" 2 1977.9432 5.99 86600 18556 3 1977.941251 660.3217 Cullin-3 OS=Homo sapiens OX=9606 GN=CUL3 PE=1 SV=2 4.65 2987.4 - 1.17E+06 - - - -0.9955 - 2.197 0.395 - 119.6 1 2 0 -0.002 17 0 0 0 2.32E+07 3.88E+06 - - - 4.9317 1 221125_WJC_METTL3_EV_vs_WT_F06.18557.18557.3 1.24E-05 19/68 K.DNTRPGANSPEMWSEAIK.L "sp|Q92499|DDX1_HUMAN,tr|A0A087X2G1|A0A087X2G1_HUMAN,tr|A0A7I2V430|A0A7I2V430_HUMAN,tr|A0A7I2V4F0|A0A7I2V4F0_HUMAN,tr|A0A087WZ71|A0A087WZ71_HUMAN,tr|A0A7I2YQ77|A0A7I2YQ77_HUMAN" 6 2001.9214 1.68 86601 18557 3 2001.923935 668.3144 ATP-dependent RNA helicase DDX1 OS=Homo sapiens OX=9606 GN=DDX1 PE=1 SV=2 4.68 2987.5 - 1.66E+06 - - - 1.2468 - 3.172 0.428 - 430.9 1 2 0 0.0025 18 0 0 0 1.99E+08 1.18E+08 - - - 6.1856 1 221125_WJC_METTL3_EV_vs_WT_F06.18561.18561.3 5.81E-11 23/72 R.EGRPSGEAFVELESEDEVK.L "sp|P31943|HNRH1_HUMAN,tr|E7EQJ0|E7EQJ0_HUMAN,tr|D6RIH9|D6RIH9_HUMAN,tr|D6RJ04|D6RJ04_HUMAN,tr|D6RFM3|D6RFM3_HUMAN,tr|E9PCY7|E9PCY7_HUMAN,tr|D6RIT2|D6RIT2_HUMAN,tr|D6R9T0|D6R9T0_HUMAN,tr|D6RIU0|D6RIU0_HUMAN,tr|D6RAM1|D6RAM1_HUMAN,tr|D6RBM0|D6RBM0_HUMAN,tr|G8JLB6|G8JLB6_HUMAN,tr|D6RDL0|D6RDL0_HUMAN,tr|D6RDU3|D6RDU3_HUMAN,tr|E7EN40|E7EN40_HUMAN" 15 2105.9753 1.26 86603 18561 3 2105.975545 702.999 Heterogeneous nuclear ribonucleoprotein H OS=Homo sapiens OX=9606 GN=HNRNPH1 PE=1 SV=4 4.06 2988 - 1.86E+06 - - - 0.1121 - 4.772 0.643 - 861.2 1 2 0 0.0002 19 0 0 0 4.67E+08 3.71E+08 - - - 9.5482 1 221125_WJC_METTL3_EV_vs_WT_F06.18565.18565.3 1.77E-10 23/72 R.EGR[166.11]PSGEAFVELESEDEVK[136.11].L "sp|P31943|HNRH1_HUMAN,tr|E7EQJ0|E7EQJ0_HUMAN,tr|D6RIH9|D6RIH9_HUMAN,tr|D6RJ04|D6RJ04_HUMAN,tr|D6RFM3|D6RFM3_HUMAN,tr|E9PCY7|E9PCY7_HUMAN,tr|D6RIT2|D6RIT2_HUMAN,tr|D6R9T0|D6R9T0_HUMAN,tr|D6RIU0|D6RIU0_HUMAN,tr|D6RAM1|D6RAM1_HUMAN,tr|D6RBM0|D6RBM0_HUMAN,tr|G8JLB6|G8JLB6_HUMAN,tr|D6RDL0|D6RDL0_HUMAN,tr|D6RDU3|D6RDU3_HUMAN,tr|E7EN40|E7EN40_HUMAN" 15 2123.9978 1.28 86607 18565 3 2123.999239 709.0065 Heterogeneous nuclear ribonucleoprotein H OS=Homo sapiens OX=9606 GN=HNRNPH1 PE=1 SV=4 4.06 2988.4 - 1.54E+06 - - - 0.6874 - 4.228 0.601 - 712.1 1 2 0 0.0015 19 0 0 0 4.67E+08 3.65E+08 - - - 8.7822 0.999 221125_WJC_METTL3_EV_vs_WT_F06.18574.18574.3 2.48E-08 17/68 K.YVHYEIDAC[160.03]MDSEAPGSK[136.11].D "sp|Q86U44|MTA70_HUMAN,tr|H0YFV6|H0YFV6_HUMAN" 2 2078.8805 0.01 86613 18574 3 2079.877642 693.9674 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 4.31 2989.3 - 3.49E+06 - - - 479.6572 - 3.149 0.659 - 302.6 1 2 0 0.9971 18 0 0 0 1.65E+06 2.04E+08 - - - 8.4673 0.8877 221125_WJC_METTL3_EV_vs_WT_F06.18581.18581.4 0.0165 Aug-90 K.RNSISDDDTDSEDELR[166.11].M "sp|Q76FK4|NOL8_HUMAN,tr|F5GWN9|F5GWN9_HUMAN,tr|F5H101|F5H101_HUMAN,tr|F8WE42|F8WE42_HUMAN" 4 1875.7958 - 86617 18581 4 1875.779925 469.9562 Nucleolar protein 8 OS=Homo sapiens OX=9606 GN=NOL8 PE=1 SV=1 3.85 2990.1 - 781974 - - - -8.4513 - 1.351 0.303 - 35.1 1 2 0 -0.0159 16 0 0 0 - - - - - 1.9649 1 221125_WJC_METTL3_EV_vs_WT_F06.18586.18586.3 1.23E-12 22/96 K.DFYGPNSQGSHVASGFPAEQAGGLK.S sp|Q5T481|RBM20_HUMAN 1 2520.167 1.82 86620 18586 3 2520.164145 841.0629 RNA-binding protein 20 OS=Homo sapiens OX=9606 GN=RBM20 PE=1 SV=3 5.32 2990.8 - 1.30E+06 - - - -1.1194 - 3.901 0.694 - 387.1 1 2 0 -0.0028 25 0 0 0 1.08E+08 5.95E+07 - - - 9.4083 0.9827 221125_WJC_METTL3_EV_vs_WT_F06.18587.18587.2 1.24E-07 14/38 G.GSGGGFSASSLGGGFGGGSR.G sp|P35527|K1C9_HUMAN 1 1657.7445 999 86621 18587 2 1657.739986 829.8795 "Keratin, type I cytoskeletal 9 OS=Homo sapiens OX=9606 GN=KRT9 PE=1 SV=3" 9.75 2990.9 - 654779 - - - -2.6995 - 2.723 0.57 - 422.6 1 1 0 -0.0045 20 0 0 0 2.97E+07 0.00E+00 - - - 5.7124 1 221125_WJC_METTL3_EV_vs_WT_F06.18594.18594.3 1.88E-07 14/68 K.SKPGAAMVEMADGYAVDR.A "sp|P14866|HNRPL_HUMAN,tr|M0QYT0|M0QYT0_HUMAN,tr|A0A3B3ITJ4|A0A3B3ITJ4_HUMAN,tr|M0QXS5|M0QXS5_HUMAN" 4 1866.8604 0.71 86626 18594 3 1866.859409 623.2941 Heterogeneous nuclear ribonucleoprotein L OS=Homo sapiens OX=9606 GN=HNRNPL PE=1 SV=2 4.56 2991.8 - 646660 - - - -0.541 - 3.033 0.565 - 265.2 1 2 0 -0.001 18 0 0 0 1.21E+07 1.70E+07 - - - 7.6018 1 221125_WJC_METTL3_EV_vs_WT_F06.18598.18598.2 3.40E-15 18/38 R.FSSC[160.03]GGGGGSFGAGGGFGSR.S sp|P04264|K2C1_HUMAN 1 1764.7274 999 86628 18598 2 1764.728369 883.371 "Keratin, type II cytoskeletal 1 OS=Homo sapiens OX=9606 GN=KRT1 PE=1 SV=6" 8.25 2992.4 - 622257 - - - 0.5315 - 3.919 0.788 - 541.8 1 2 0 0.0009 20 0 0 0 6.22E+07 0.00E+00 - - - 8.2188 1 221125_WJC_METTL3_EV_vs_WT_F06.18599.18599.3 3.49E-08 17/76 K.LAASGEGGLQELSGHFENQK.V "sp|Q16643|DREB_HUMAN,tr|D6RFI1|D6RFI1_HUMAN" 2 2070.997 0.76 86629 18599 3 2070.998322 691.3396 Drebrin OS=Homo sapiens OX=9606 GN=DBN1 PE=1 SV=4 4.75 2992.5 - 864328 - - - 0.6156 - 3.02 0.499 - 247.6 1 2 0 0.0013 20 0 0 0 1.05E+08 1.39E+08 - - - 6.7844 0.9948 221125_WJC_METTL3_EV_vs_WT_F06.18600.18600.4 0.00481 11/102 R.SLHTPSLRPSDVVQVSLK.F "sp|O43548|TGM5_HUMAN,tr|A0A087WVW4|A0A087WVW4_HUMAN,tr|A0A087WVS3|A0A087WVS3_HUMAN,tr|A0A087WZC4|A0A087WZC4_HUMAN" 4 1962.0898 15.14 86630 18600 4 1962.096044 491.5297 Protein-glutamine gamma-glutamyltransferase 5 OS=Homo sapiens OX=9606 GN=TGM5 PE=1 SV=4 8.49 2992.6 - 466257 - - - 3.1696 - 2.204 0.275 - 91.4 1 2 0 0.0062 18 0 0 0 7.85E+06 5.18E+05 - - - 1.8886 1 221125_WJC_METTL3_EV_vs_WT_F06.18603.18603.3 7.84E-12 20/96 K.DFYGPNSQGSHVASGFPAEQAGGLK[136.11].S sp|Q5T481|RBM20_HUMAN 1 2528.1812 1.82 86631 18603 3 2528.179156 843.7343 RNA-binding protein 20 OS=Homo sapiens OX=9606 GN=RBM20 PE=1 SV=3 5.32 2993 - 1.44E+06 - - - -0.795 - 3.621 0.634 - 243.3 1 2 0 -0.002 25 0 0 0 1.08E+08 5.95E+07 - - - 8.5683 0.9999 221125_WJC_METTL3_EV_vs_WT_F06.18609.18609.3 1.38E-08 15/72 K.DVATVAFC[160.03]DAQSTQEIHEK.V "sp|Q13363|CTBP1_HUMAN,tr|E7ESU7|E7ESU7_HUMAN,tr|E7EUB3|E7EUB3_HUMAN,tr|D6RAX2|D6RAX2_HUMAN,tr|E7EPF8|E7EPF8_HUMAN,tr|E9PGB1|E9PGB1_HUMAN" 6 2147.9793 2.6 86634 18609 3 2147.970822 717.0004 C-terminal-binding protein 1 OS=Homo sapiens OX=9606 GN=CTBP1 PE=1 SV=2 4.31 2993.7 - 1.18E+06 - - - -3.9693 - 3.297 0.624 - 201.8 1 2 0 -0.0085 19 0 0 0 4.56E+07 1.75E+07 - - - 8.4256 1 221125_WJC_METTL3_EV_vs_WT_F06.18613.18613.3 3.21E-05 15/52 K.SGEEGMPDLAHVMR.L "sp|O75688|PPM1B_HUMAN,tr|B8ZZF0|B8ZZF0_HUMAN,tr|A0A3B3IS24|A0A3B3IS24_HUMAN,tr|C9JIR6|C9JIR6_HUMAN" 4 1527.681 3.96 86636 18613 3 1527.680599 510.2343 Protein phosphatase 1B OS=Homo sapiens OX=9606 GN=PPM1B PE=1 SV=1 4.65 2994.3 - 533669 - - - -0.2612 - 3.054 0.513 - 402.6 1 2 0 -0.0004 14 0 0 0 4.98E+07 1.26E+07 - - - 7.2263 1 221125_WJC_METTL3_EV_vs_WT_F06.18618.18618.3 1.35E-10 18/76 R.DQLVIPDGQEEEQEAAGEGR.N sp|Q8NBJ4|GOLM1_HUMAN 1 2168.9822 1.33 86640 18618 3 2168.98007 724.0013 Golgi membrane protein 1 OS=Homo sapiens OX=9606 GN=GOLM1 PE=1 SV=1 3.71 2994.8 - 704202 - - - -0.9751 - 3.48 0.662 - 327.3 1 2 0 -0.0021 20 0 0 0 2.82E+07 2.12E+07 - - - 8.9454 0.9828 221125_WJC_METTL3_EV_vs_WT_F06.18620.18620.3 0.575 Sep-44 R.KNYGVTFPIFHK.L "sp|Q8TED1|GPX8_HUMAN,tr|E7ETY7|E7ETY7_HUMAN" 2 1449.7769 0.98 86642 18620 3 1449.778118 484.2662 Probable glutathione peroxidase 8 OS=Homo sapiens OX=9606 GN=GPX8 PE=1 SV=2 9.7 2995 - 400342 - - - 0.8601 - 1.64 0.143 - 74.8 1 2 0 0.0012 12 0 0 0 8.64E+06 8.85E+06 - - - 1.5052 0.9999 221125_WJC_METTL3_EV_vs_WT_F06.18623.18623.4 7.99E-05 18/78 K.DSQQFHLVPVHLDR.V sp|Q9H1E1|RNAS7_HUMAN 1 1689.8587 19.22 86643 18623 4 1689.858206 423.472 Ribonuclease 7 OS=Homo sapiens OX=9606 GN=RNASE7 PE=1 SV=2 5.98 2995.6 - 791668 - - - -0.2941 - 2.857 0.441 - 319.6 1 2 0 -0.0005 14 0 0 0 3.61E+07 1.88E+06 - - - 3.4464 0.9926 221125_WJC_METTL3_EV_vs_WT_F06.18630.18630.4 0.00866 Nov-78 R.EDLHILFSNHGEIK[136.11].W sp|P05455|LA_HUMAN 1 1658.8508 1.2 86649 18630 4 1658.847627 415.72 Lupus La protein OS=Homo sapiens OX=9606 GN=SSB PE=1 SV=2 5.28 2996.4 - 546013 - - - -1.8947 - 2.029 0.219 - 72.3 1 2 0 -0.0031 14 0 0 0 1.74E+07 1.45E+07 - - - 1.3888 1 221125_WJC_METTL3_EV_vs_WT_F06.18640.18640.3 3.06E-09 16/52 K.HWPFMVVNDAGRPK.V "sp|P11142|HSP7C_HUMAN,tr|E9PQQ4|E9PQQ4_HUMAN,tr|E9PNE6|E9PNE6_HUMAN,tr|E9PKE3|E9PKE3_HUMAN,tr|E9PN89|E9PN89_HUMAN,tr|E9PLF4|E9PLF4_HUMAN,tr|E9PK54|E9PK54_HUMAN,tr|E9PN25|E9PN25_HUMAN,tr|E9PPY6|E9PPY6_HUMAN,tr|E9PQK7|E9PQK7_HUMAN" 10 1652.8246 0.1 86656 18640 3 1652.826648 551.9488 Heat shock cognate 71 kDa protein OS=Homo sapiens OX=9606 GN=HSPA8 PE=1 SV=1 8.75 2997.4 - 766239 - - - 1.2597 - 3.128 0.582 - 448 1 2 0 0.0021 14 0 0 0 1.57E+08 1.55E+09 - - - 8.0588 1 221125_WJC_METTL3_EV_vs_WT_F06.18643.18643.2 2.74E-10 13/38 R.DQLVIPDGQEEEQEAAGEGR.N sp|Q8NBJ4|GOLM1_HUMAN 1 2168.9822 3.6 86658 18643 2 2168.981224 1085.4984 Golgi membrane protein 1 OS=Homo sapiens OX=9606 GN=GOLM1 PE=1 SV=1 3.71 2997.8 - 670279 - - - -0.4431 - 2.86 0.671 - 268.1 1 2 0 -0.001 20 0 0 0 1.53E+07 4.26E+06 - - - 6.5802 1 221125_WJC_METTL3_EV_vs_WT_F06.18648.18648.3 6.64E-12 26/88 R.LC[160.03]C[160.03]QEDPELDSDKDETGAYLIDR.D sp|Q14681|KCTD2_HUMAN 1 2741.1796 18.43 86661 18648 3 2741.175872 914.7338 BTB\POZ domain-containing protein KCTD2 OS=Homo sapiens OX=9606 GN=KCTD2 PE=1 SV=3 3.8 2998.4 - 727192 - - - -1.375 - 3.986 0.766 - 633.8 1 2 1 -0.0038 23 0 0 0 1.75E+07 9.50E+05 - - - 10.323 0.9998 221125_WJC_METTL3_EV_vs_WT_F06.18651.18651.4 0.000529 19/90 K.TYFPHFDLSHGSAQVK.G "sp|P69905|HBA_HUMAN,tr|G3V1N2|G3V1N2_HUMAN,tr|A0A2R8Y7C0|A0A2R8Y7C0_HUMAN" 3 1832.8846 121.33 86663 18651 4 1832.884643 459.2284 Hemoglobin subunit alpha OS=Homo sapiens OX=9606 GN=HBA1 PE=1 SV=2 6.61 2998.7 - 3.13E+06 - - - 0.0327 - 2.493 0.391 - 265.2 1 2 0 0.0001 16 0 0 0 6.97E+07 5.74E+05 - - - 2.951 1 221125_WJC_METTL3_EV_vs_WT_F06.18654.18654.3 5.61E-06 20/76 K.LAASGEGGLQELSGHFENQK[136.11].V "sp|Q16643|DREB_HUMAN,tr|D6RFI1|D6RFI1_HUMAN" 2 2079.0112 0.72 86666 18654 3 2079.010006 694.011 Drebrin OS=Homo sapiens OX=9606 GN=DBN1 PE=1 SV=4 4.75 2998.9 - 5.73E+06 - - - -0.5969 - 3.052 0.441 - 314.2 1 2 0 -0.0012 20 0 0 0 1.09E+08 1.50E+08 - - - 6.1633 0.999 221125_WJC_METTL3_EV_vs_WT_F06.18655.18655.3 1.74E-08 19/72 K.DVATVAFC[160.03]DAQSTQEIHEK[136.11].V "sp|Q13363|CTBP1_HUMAN,tr|E7ESU7|E7ESU7_HUMAN,tr|E7EUB3|E7EUB3_HUMAN,tr|D6RAX2|D6RAX2_HUMAN,tr|E7EPF8|E7EPF8_HUMAN,tr|E9PGB1|E9PGB1_HUMAN" 6 2155.9935 2.6 86667 18655 3 2155.978724 719.6718 C-terminal-binding protein 1 OS=Homo sapiens OX=9606 GN=CTBP1 PE=1 SV=2 4.31 2998.9 - 1.19E+06 - - - -6.8757 - 2.713 0.56 - 295.1 1 2 0 -0.0148 19 0 0 0 4.56E+07 1.75E+07 - - - 7.2314 1 221125_WJC_METTL3_EV_vs_WT_F06.18656.18656.3 6.22E-10 14/52 K.SGEEGMPDLAHVMR[166.11].L "sp|O75688|PPM1B_HUMAN,tr|B8ZZF0|B8ZZF0_HUMAN,tr|A0A3B3IS24|A0A3B3IS24_HUMAN,tr|C9JIR6|C9JIR6_HUMAN" 4 1537.6893 4.46 86668 18656 3 1537.68762 513.5704 Protein phosphatase 1B OS=Homo sapiens OX=9606 GN=PPM1B PE=1 SV=1 4.65 2999.1 - 334889 - - - -1.0717 - 2.843 0.644 - 293.4 1 2 0 -0.0016 14 0 0 0 4.08E+07 9.15E+06 - - - 8.4963 1 221125_WJC_METTL3_EV_vs_WT_F06.18665.18665.3 3.11E-06 15/88 R.GNFGGSFAGSFGGAGGHAPGVAR[166.11].K "sp|P52272|HNRPM_HUMAN,tr|M0R2I7|M0R2I7_HUMAN,tr|M0QY96|M0QY96_HUMAN,tr|A0A087X0X3|A0A087X0X3_HUMAN" 4 2043.9539 2.23 86674 18665 3 2043.956405 682.3252 Heterogeneous nuclear ribonucleoprotein M OS=Homo sapiens OX=9606 GN=HNRNPM PE=1 SV=3 9.76 3000.2 - 275603 - - - 1.2305 - 2.749 0.492 - 155.9 1 2 0 0.0025 23 0 0 0 2.26E+07 1.01E+07 - - - 6.3969 1 221125_WJC_METTL3_EV_vs_WT_F06.18669.18669.4 3.39E-11 27/132 R.YHVPVVVVPEGSASDTHEQAILR[166.11].L "sp|P04844|RPN2_HUMAN,tr|Q5JYR7|Q5JYR7_HUMAN,tr|Q5JYR4|Q5JYR4_HUMAN" 3 2512.295 1.07 86676 18669 4 2512.294173 629.081 Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit 2 OS=Homo sapiens OX=9606 GN=RPN2 PE=1 SV=3 5.27 3000.6 - 3.91E+06 - - - -0.3121 - 4.068 0.591 - 642.5 1 2 0 -0.0008 23 0 0 0 1.50E+08 1.41E+08 - - - 4.8244 1 221125_WJC_METTL3_EV_vs_WT_F06.18670.18670.3 1.83E-07 19/68 K.K[136.11]LETAVNLAWTAGNSNTR[166.11].F sp|P21796|VDAC1_HUMAN 1 1963.0242 1.42 86677 18670 3 1963.024732 655.3487 Voltage-dependent anion-selective channel protein 1 OS=Homo sapiens OX=9606 GN=VDAC1 PE=1 SV=2 8.75 3000.6 - 3.34E+06 - - - 0.2669 - 3.676 0.59 - 414.7 1 2 0 0.0005 18 0 0 0 3.61E+08 2.53E+08 - - - 8.3594 1 221125_WJC_METTL3_EV_vs_WT_F06.18671.18671.3 0.000174 15/56 K.K[136.11]SDIDEIVLVGGSTR[166.11].L "sp|P11021|BIP_HUMAN,tr|A0A7P0TB36|A0A7P0TB36_HUMAN" 2 1605.8693 0.47 86678 18671 3 1605.870095 536.297 Endoplasmic reticulum chaperone BiP OS=Homo sapiens OX=9606 GN=HSPA5 PE=1 SV=2 4.56 3000.7 - 1.66E+06 - - - 0.5131 - 2.445 0.463 - 278.6 1 2 0 0.0008 15 0 0 0 2.17E+07 4.60E+07 - - - 6.0347 0.9922 221125_WJC_METTL3_EV_vs_WT_F06.18673.18673.4 0.134 10/102 R.AIQFLHQDSPSLIHGDIK.S "sp|P51617|IRAK1_HUMAN,tr|H7C224|H7C224_HUMAN,tr|D3YTB5|D3YTB5_HUMAN" 3 2018.0585 1.35 86680 18673 4 2018.062669 505.5219 Interleukin-1 receptor-associated kinase 1 OS=Homo sapiens OX=9606 GN=IRAK1 PE=1 SV=2 5.98 3000.9 - 766969 - - - 2.0535 - 1.783 0.231 - 57.4 1 2 0 0.0041 18 0 0 0 1.50E+07 1.12E+07 - - - 1.4336 1 221125_WJC_METTL3_EV_vs_WT_F06.18678.18678.3 5.02E-12 21/80 K.AVK[136.11]EEGQDPDEIGIELEATSK[136.11].K sp|Q14151|SAFB2_HUMAN 1 2273.1246 8.02 86683 18678 3 2273.124474 758.7155 Scaffold attachment factor B2 OS=Homo sapiens OX=9606 GN=SAFB2 PE=1 SV=1 4 3001.6 - 1.11E+06 - - - -0.0343 - 3.918 0.676 - 487.1 1 2 1 -0.0001 21 0 0 0 1.43E+08 1.78E+07 - - - 9.3506 0.9997 221125_WJC_METTL3_EV_vs_WT_F06.18679.18679.4 0.000281 18/108 K.GEHSIVYLK[136.11]PSYAFGSVGK[136.11].E sp|Q02790|FKBP4_HUMAN 1 2054.0808 1.24 86684 18679 4 2054.078134 514.5275 Peptidyl-prolyl cis-trans isomerase FKBP4 OS=Homo sapiens OX=9606 GN=FKBP4 PE=1 SV=3 8.44 3001.7 - 727642 - - - -1.2867 - 3.045 0.343 - 264.4 1 2 0 -0.0026 19 0 0 0 4.19E+07 3.37E+07 - - - 2.5874 1 221125_WJC_METTL3_EV_vs_WT_F06.18680.18680.2 6.72E-10 17/34 K.GGGGYTC[160.03]QSGSGWDEFTK.H sp|P15924|DESP_HUMAN 1 1892.7635 116.57 86685 18680 2 1892.765338 947.389 Desmoplakin OS=Homo sapiens OX=9606 GN=DSP PE=1 SV=3 4.37 3001.8 - 611506 - - - 0.9489 - 3.303 0.753 - 1009.4 1 2 0 0.0018 18 0 0 0 1.18E+08 1.01E+06 - - - 7.5396 1 221125_WJC_METTL3_EV_vs_WT_F06.18688.18688.3 2.00E-07 17/72 K.GEHSIVYLK[136.11]PSYAFGSVGK[136.11].E sp|Q02790|FKBP4_HUMAN 1 2054.0808 1.42 86691 18688 3 2054.078362 685.7009 Peptidyl-prolyl cis-trans isomerase FKBP4 OS=Homo sapiens OX=9606 GN=FKBP4 PE=1 SV=3 8.44 3002.9 - 615155 - - - -1.1757 - 3.473 0.534 - 438.2 1 2 0 -0.0024 19 0 0 0 2.23E+07 1.57E+07 - - - 7.5517 0.985 221125_WJC_METTL3_EV_vs_WT_F06.18689.18689.3 0.0293 Sep-60 K.NLEQYNK[136.11]LDQDLNEVK[136.11].A sp|Q9UQE7|SMC3_HUMAN 1 1977.9978 0.001 86692 18689 3 1978.0015 660.3399 Structural maintenance of chromosomes protein 3 OS=Homo sapiens OX=9606 GN=SMC3 PE=1 SV=2 4.32 3003 - 558286 - - - 1.8529 - 1.799 0.254 - 61.5 1 2 1 0.0037 16 0 0 0 0.00E+00 1.16E+07 - - - 2.8776 1 221125_WJC_METTL3_EV_vs_WT_F06.18695.18695.3 1.15E-09 17/68 K.KLETAVNLAWTAGNSNTR.F sp|P21796|VDAC1_HUMAN 1 1945.0017 1.42 86696 18695 3 1945.002686 649.3412 Voltage-dependent anion-selective channel protein 1 OS=Homo sapiens OX=9606 GN=VDAC1 PE=1 SV=2 8.75 3003.6 - 1.33E+07 - - - 0.4874 - 3.418 0.574 - 361.4 1 2 0 0.0009 18 0 0 0 3.61E+08 2.53E+08 - - - 7.9997 1 221125_WJC_METTL3_EV_vs_WT_F06.18696.18696.3 1.92E-10 23/92 R.LLTSHTGNTSNSEDILSSAC[160.03]YTVR.N sp|Q13835|PKP1_HUMAN 1 2625.2341 33.3 86697 18696 3 2625.237069 876.0853 Plakophilin-1 OS=Homo sapiens OX=9606 GN=PKP1 PE=1 SV=2 5.32 3003.7 - 1.96E+06 - - - 1.1462 - 4.199 0.703 - 425.2 1 2 0 0.003 24 0 0 0 3.96E+07 1.19E+06 - - - 9.7095 0.9873 221125_WJC_METTL3_EV_vs_WT_F06.18699.18699.3 9.15E-05 13/120 K.LNPGAHELSPGQSSAFTSQGPGAYPGSAAAA.A sp|O95409|ZIC2_HUMAN 1 2897.358 - 86700 18699 3 2897.359837 966.7933 Zinc finger protein ZIC 2 OS=Homo sapiens OX=9606 GN=ZIC2 PE=1 SV=2 5.24 3004.1 - 503762 - - - 0.6292 - 2.582 0.384 - 61.9 1 1 0 0.0018 31 0 0 0 - - - - - 5.003 1 221125_WJC_METTL3_EV_vs_WT_F06.18708.18708.2 1.22E-09 24/34 K.KLETAVNLAWTAGNSNTR.F sp|P21796|VDAC1_HUMAN 1 1945.0017 1.53 86707 18708 2 1945.003205 973.5081 Voltage-dependent anion-selective channel protein 1 OS=Homo sapiens OX=9606 GN=VDAC1 PE=1 SV=2 8.75 3005.1 - 686547 - - - 0.7542 - 4.625 0.673 - 2347.2 1 2 0 0.0015 18 0 0 0 1.31E+07 8.59E+06 - - - 7.7765 0.9988 221125_WJC_METTL3_EV_vs_WT_F06.18717.18717.3 0.000952 16/92 K.TTTYTQGVPPSQGDLEYQMSTTAR.A "sp|P14923|PLAK_HUMAN,tr|K7ERP3|K7ERP3_HUMAN,tr|C9JKY1|C9JKY1_HUMAN,tr|C9JK18|C9JK18_HUMAN,tr|C9JTX4|C9JTX4_HUMAN,tr|C9JPI2|C9JPI2_HUMAN,tr|C9J826|C9J826_HUMAN" 7 2631.2123 41.99 86714 18717 3 2631.199445 878.078 Junction plakoglobin OS=Homo sapiens OX=9606 GN=JUP PE=1 SV=3 4.37 3006.2 - 897380 - - - -4.8708 - 2.242 0.448 - 70.1 1 2 0 -0.0128 24 0 0 0 3.15E+07 7.49E+05 - - - 5.4064 1 221125_WJC_METTL3_EV_vs_WT_F06.18720.18720.3 3.27E-09 19/52 K.HWPFMVVNDAGR[166.11]PK[136.11].V "sp|P11142|HSP7C_HUMAN,tr|E9PQQ4|E9PQQ4_HUMAN,tr|E9PNE6|E9PNE6_HUMAN,tr|E9PKE3|E9PKE3_HUMAN,tr|E9PN89|E9PN89_HUMAN,tr|E9PLF4|E9PLF4_HUMAN,tr|E9PK54|E9PK54_HUMAN,tr|E9PN25|E9PN25_HUMAN,tr|E9PPY6|E9PPY6_HUMAN,tr|E9PQK7|E9PQK7_HUMAN" 10 1670.847 0.1 86716 18720 3 1670.845696 557.9563 Heat shock cognate 71 kDa protein OS=Homo sapiens OX=9606 GN=HSPA8 PE=1 SV=1 8.75 3006.5 - 3.02E+06 - - - -0.802 - 3.064 0.623 - 643.4 1 2 0 -0.0013 14 0 0 0 1.52E+08 1.49E+09 - - - 8.4612 0.9999 221125_WJC_METTL3_EV_vs_WT_F06.18722.18722.2 9.37E-05 15/28 R.GALQNIIPASTGAAK[136.11].A "sp|P04406|G3P_HUMAN,tr|E7EUT5|E7EUT5_HUMAN" 2 1418.7973 1.06 86717 18722 2 1418.795623 710.4059 Glyceraldehyde-3-phosphate dehydrogenase OS=Homo sapiens OX=9606 GN=GAPDH PE=1 SV=3 8.75 3006.7 - 1.71E+06 - - - -1.1665 - 2.867 0.485 - 549.3 1 2 0 -0.0017 15 0 0 0 9.05E+07 8.51E+07 - - - 5.2122 1 221125_WJC_METTL3_EV_vs_WT_F06.18725.18725.3 6.11E-10 19/96 K.LVQDVANNTNEEAGDGTTTATVLAR.S "sp|P10809|CH60_HUMAN,tr|C9JL25|C9JL25_HUMAN,tr|A0A7I2V2X6|A0A7I2V2X6_HUMAN,tr|A0A7I2YQK6|A0A7I2YQK6_HUMAN,tr|A0A7I2V599|A0A7I2V599_HUMAN,tr|E7EXB4|E7EXB4_HUMAN,tr|A0A7I2YQ71|A0A7I2YQ71_HUMAN,tr|E7ESH4|E7ESH4_HUMAN,tr|A0A7I2V5M1|A0A7I2V5M1_HUMAN,tr|A0A7I2V5K3|A0A7I2V5K3_HUMAN,tr|A0A7I2V369|A0A7I2V369_HUMAN" 11 2559.2413 1.84 86720 18725 3 2559.241002 854.0877 "60 kDa heat shock protein, mitochondrial OS=Homo sapiens OX=9606 GN=HSPD1 PE=1 SV=2" 3.92 3007.1 - 1.39E+06 - - - -0.0981 - 3.75 0.677 - 197.6 1 2 0 -0.0003 25 0 0 0 3.73E+07 2.02E+07 - - - 9.1287 1 221125_WJC_METTL3_EV_vs_WT_F06.18729.18729.2 9.23E-08 20/34 K.K[136.11]LETAVNLAWTAGNSNTR[166.11].F sp|P21796|VDAC1_HUMAN 1 1963.0242 1.53 86724 18729 2 1963.023432 982.5194 Voltage-dependent anion-selective channel protein 1 OS=Homo sapiens OX=9606 GN=VDAC1 PE=1 SV=2 8.75 3007.6 - 549773 - - - -0.3953 - 4.621 0.703 - 1417.1 1 2 0 -0.0008 18 0 0 0 1.31E+07 8.59E+06 - - - 7.9962 0.9999 221125_WJC_METTL3_EV_vs_WT_F06.18733.18733.3 1.43E-06 15/52 K.TKEYELLSDELNQK.S sp|P33176|KINH_HUMAN 1 1708.8519 1.55 86726 18733 3 1708.852661 570.6246 Kinesin-1 heavy chain OS=Homo sapiens OX=9606 GN=KIF5B PE=1 SV=1 4.41 3008.1 - 715449 - - - 0.4184 - 2.923 0.474 - 372.8 1 2 1 0.0007 14 0 0 0 2.23E+07 1.44E+07 - - - 6.6749 0.9998 221125_WJC_METTL3_EV_vs_WT_F06.18734.18734.2 3.38E-08 17/28 R.GALQNIIPASTGAAK.A "sp|P04406|G3P_HUMAN,tr|E7EUT5|E7EUT5_HUMAN" 2 1410.7831 1.06 86727 18734 2 1410.786201 706.3988 Glyceraldehyde-3-phosphate dehydrogenase OS=Homo sapiens OX=9606 GN=GAPDH PE=1 SV=3 8.75 3008.2 - 2.48E+06 - - - 2.2137 - 2.641 0.56 - 720.8 1 2 0 0.0031 15 0 0 0 9.05E+07 8.51E+07 - - - 5.5638 0.9999 221125_WJC_METTL3_EV_vs_WT_F06.18743.18743.3 2.94E-05 19/60 K.RYEEELEINDFPQTAR.W "sp|Q7L014|DDX46_HUMAN,tr|A0A0C4DG89|A0A0C4DG89_HUMAN" 2 2008.949 0.94 86732 18743 3 2008.942009 670.657 Probable ATP-dependent RNA helicase DDX46 OS=Homo sapiens OX=9606 GN=DDX46 PE=1 SV=2 4.25 3009.4 - 1.26E+06 - - - -3.4969 - 3.363 0.559 - 538.9 1 2 0 -0.007 16 0 0 0 2.65E+07 2.82E+07 - - - 7.8823 1 221125_WJC_METTL3_EV_vs_WT_F06.18745.18745.3 2.90E-12 19/64 K.HSNSNSVDDTIVALNMR.A "sp|P52948|NUP98_HUMAN,tr|A0A3B3ITD8|A0A3B3ITD8_HUMAN" 2 1871.8796 1.66 86733 18745 3 1871.876009 624.9671 Nuclear pore complex protein Nup98-Nup96 OS=Homo sapiens OX=9606 GN=NUP98 PE=1 SV=4 5.21 3009.6 - 4.36E+06 - - - -1.9045 - 3.487 0.712 - 433 1 2 0 -0.0036 17 0 0 0 2.83E+08 1.71E+08 - - - 9.6326 0.9998 221125_WJC_METTL3_EV_vs_WT_F06.18746.18746.3 6.09E-09 19/76 R.SPWSNK[136.11]YDPPLEDGAMPSAR[166.11].L "sp|P47756|CAPZB_HUMAN,tr|B1AK87|B1AK87_HUMAN,tr|B1AK88|B1AK88_HUMAN,tr|A0A6I8PRV6|A0A6I8PRV6_HUMAN,tr|B1AK85|B1AK85_HUMAN" 5 2235.0385 0.4 86734 18746 3 2235.032063 746.0201 F-actin-capping protein subunit beta OS=Homo sapiens OX=9606 GN=CAPZB PE=1 SV=4 4.56 3009.7 - 767590 - - - -2.897 - 3.41 0.532 - 436.8 1 2 1 -0.0065 20 0 0 0 9.96E+06 2.46E+07 - - - 7.4455 1 221125_WJC_METTL3_EV_vs_WT_F06.18747.18747.3 2.07E-15 26/108 K.APEPVC[160.03]AAPGPPHGPAGAASNFYSAVGR.N sp|P31277|HXD11_HUMAN 1 2704.2816 3.6 86735 18747 3 2704.274545 902.4345 Homeobox protein Hox-D11 OS=Homo sapiens OX=9606 GN=HOXD11 PE=3 SV=3 6.78 3009.9 - 773694 - - - -2.6159 - 4.263 0.702 - 471.5 1 2 0 -0.0071 28 0 0 0 2.27E+07 6.31E+06 - - - 9.7005 1 221125_WJC_METTL3_EV_vs_WT_F06.18751.18751.3 2.61E-12 19/64 K.HSNSNSVDDTIVALNMR[166.11].A "sp|P52948|NUP98_HUMAN,tr|A0A3B3ITD8|A0A3B3ITD8_HUMAN" 2 1881.8878 1.68 86737 18751 3 1881.886585 628.3032 Nuclear pore complex protein Nup98-Nup96 OS=Homo sapiens OX=9606 GN=NUP98 PE=1 SV=4 5.21 3010.4 - 5.00E+06 - - - -0.669 - 3.4 0.698 - 355.2 1 2 0 -0.0013 17 0 0 0 2.72E+08 1.62E+08 - - - 9.4133 0.9999 221125_WJC_METTL3_EV_vs_WT_F06.18759.18759.3 5.73E-10 21/76 R.SPWSNKYDPPLEDGAMPSAR.L "sp|P47756|CAPZB_HUMAN,tr|B1AK87|B1AK87_HUMAN,tr|B1AK88|B1AK88_HUMAN,tr|A0A6I8PRV6|A0A6I8PRV6_HUMAN,tr|B1AK85|B1AK85_HUMAN" 5 2217.0161 0.4 86743 18759 3 2217.021223 740.0126 F-actin-capping protein subunit beta OS=Homo sapiens OX=9606 GN=CAPZB PE=1 SV=4 4.56 3011.4 - 716725 - - - 2.3252 - 3.654 0.54 - 607.3 1 2 1 0.0052 20 0 0 0 9.96E+06 2.46E+07 - - - 7.7027 1 221125_WJC_METTL3_EV_vs_WT_F06.18763.18763.3 3.18E-06 18/56 K.QNLSELEQLNENLK[136.11]K[136.11].V "sp|Q15643|TRIPB_HUMAN,tr|H0YJ97|H0YJ97_HUMAN" 2 1814.9709 1.23 86745 18763 3 1814.971595 605.9976 Thyroid receptor-interacting protein 11 OS=Homo sapiens OX=9606 GN=TRIP11 PE=1 SV=3 4.79 3011.9 - 1.43E+06 - - - 0.3873 - 3.212 0.518 - 507.9 1 2 0 0.0007 15 0 0 0 7.93E+07 6.45E+07 - - - 7.3598 0.9998 221125_WJC_METTL3_EV_vs_WT_F06.18764.18764.2 4.89E-12 19/32 K.HSNSNSVDDTIVALNMR[166.11].A "sp|P52948|NUP98_HUMAN,tr|A0A3B3ITD8|A0A3B3ITD8_HUMAN" 2 1881.8878 0.32 86746 18764 2 1881.890936 941.9512 Nuclear pore complex protein Nup98-Nup96 OS=Homo sapiens OX=9606 GN=NUP98 PE=1 SV=4 5.21 3012 - 560379 - - - 1.643 - 3.442 0.356 - 871.7 1 2 0 0.0031 17 0 0 0 3.57E+06 1.13E+07 - - - 4.7083 1 221125_WJC_METTL3_EV_vs_WT_F06.18766.18766.3 3.59E-06 14/64 K.HPVTGQFLYQDSNWASK.V "sp|P02786|TFR1_HUMAN,tr|G3V0E5|G3V0E5_HUMAN" 2 1976.9381 6 86748 18766 3 1976.940993 659.9866 Transferrin receptor protein 1 OS=Homo sapiens OX=9606 GN=TFRC PE=1 SV=2 6.74 3012.3 - 508068 - - - 1.476 - 3.017 0.486 - 184.7 1 2 0 0.0029 17 0 0 0 1.91E+07 3.19E+06 - - - 6.7473 1 221125_WJC_METTL3_EV_vs_WT_F06.18767.18767.3 2.93E-10 16/76 K.QTQAASASQGSASAAEVLLR[166.11].T "sp|Q969V3|NCLN_HUMAN,tr|K7EMW4|K7EMW4_HUMAN" 2 1954.9948 44.81 86749 18767 3 1954.992901 652.6722 Nicalin OS=Homo sapiens OX=9606 GN=NCLN PE=1 SV=2 6 3012.4 - 409807 - - - -0.9468 - 3.155 0.508 - 372 1 2 0 -0.0019 20 0 0 0 2.49E+08 5.55E+06 - - - 6.9907 0.9659 221125_WJC_METTL3_EV_vs_WT_F06.18774.18774.4 0.0198 15/162 K.APEPVC[160.03]AAPGPPHGPAGAASNFYSAVGR.N sp|P31277|HXD11_HUMAN 1 2704.2816 4.99 86754 18774 4 2704.269445 677.0777 Homeobox protein Hox-D11 OS=Homo sapiens OX=9606 GN=HOXD11 PE=3 SV=3 6.78 3013.3 - 632700 - - - -4.5018 - 1.984 0.239 - 62.8 1 2 0 -0.0122 28 0 0 0 2.65E+06 5.32E+05 - - - 1.5156 1 221125_WJC_METTL3_EV_vs_WT_F06.18775.18775.4 2.82E-07 14/78 K.HWPFMVVNDAGR[166.11]PK[136.11].V "sp|P11142|HSP7C_HUMAN,tr|E9PQQ4|E9PQQ4_HUMAN,tr|E9PNE6|E9PNE6_HUMAN,tr|E9PKE3|E9PKE3_HUMAN,tr|E9PN89|E9PN89_HUMAN,tr|E9PLF4|E9PLF4_HUMAN,tr|E9PK54|E9PK54_HUMAN,tr|E9PN25|E9PN25_HUMAN,tr|E9PPY6|E9PPY6_HUMAN,tr|E9PQK7|E9PQK7_HUMAN" 10 1670.847 0.14 86755 18775 4 1670.846371 418.719 Heat shock cognate 71 kDa protein OS=Homo sapiens OX=9606 GN=HSPA8 PE=1 SV=1 8.75 3013.5 - 618364 - - - -0.398 - 2.326 0.569 - 207.8 1 2 0 -0.0007 14 0 0 0 2.92E+07 2.14E+08 - - - 4.4856 1 221125_WJC_METTL3_EV_vs_WT_F06.18782.18782.3 8.09E-11 23/84 K.GAVASGHLQESATSVQTALLNR.L "sp|Q6ULP2|AFTIN_HUMAN,tr|B8ZZI9|B8ZZI9_HUMAN" 2 2209.1451 2.19 86760 18782 3 2209.14956 737.389 Aftiphilin OS=Homo sapiens OX=9606 GN=AFTPH PE=1 SV=3 6.75 3014.3 - 954948 - - - 2.0153 - 4.268 0.625 - 596.7 1 2 0 0.0045 22 0 0 0 4.44E+07 2.03E+07 - - - 8.9473 0.9999 221125_WJC_METTL3_EV_vs_WT_F06.18784.18784.4 0.00335 15/96 K.VELFHYQDGAFHTEYNR[166.11].A "sp|Q14554|PDIA5_HUMAN,tr|C9JY10|C9JY10_HUMAN" 2 2134.9736 27.84 86762 18784 4 2134.9776 534.7507 Protein disulfide-isomerase A5 OS=Homo sapiens OX=9606 GN=PDIA5 PE=1 SV=1 5.27 3014.4 - 747312 - - - 1.8628 - 2.676 0.421 - 133.4 1 2 0 0.004 17 0 0 0 2.64E+08 9.50E+06 - - - 3.231 0.9984 221125_WJC_METTL3_EV_vs_WT_F06.18788.18788.4 0.00117 Dec-66 K.LK[136.11]DYAFIHFDER[166.11].D "sp|O60506|HNRPQ_HUMAN,tr|A0A7I2YQV8|A0A7I2YQV8_HUMAN,tr|A0A7I2YQN2|A0A7I2YQN2_HUMAN,tr|A0A7I2V4Z0|A0A7I2V4Z0_HUMAN,tr|B7Z645|B7Z645_HUMAN,tr|A0A7I2V2F2|A0A7I2V2F2_HUMAN,tr|A0A7I2V346|A0A7I2V346_HUMAN,tr|A0A7I2V309|A0A7I2V309_HUMAN" 8 1570.7899 1.2 86766 18788 4 1570.791002 393.7048 Heterogeneous nuclear ribonucleoprotein Q OS=Homo sapiens OX=9606 GN=SYNCRIP PE=1 SV=2 5.38 3014.9 - 516716 - - - 0.7028 - 1.972 0.341 - 74.6 1 2 1 0.0011 12 0 0 0 7.52E+06 6.25E+06 - - - 2.4507 1 221125_WJC_METTL3_EV_vs_WT_F06.18789.18789.3 2.44E-13 20/92 R.GDVASC[160.03]NTQVAEKPVLTAVPGITR.H "sp|O75152|ZC11A_HUMAN,tr|E9PQ61|E9PQ61_HUMAN" 2 2482.285 1.14 86767 18789 3 2482.292436 828.4356 Zinc finger CCCH domain-containing protein 11A OS=Homo sapiens OX=9606 GN=ZC3H11A PE=1 SV=3 6.06 3015.1 - 504837 - - - 3.0065 - 3.679 0.717 - 340 1 2 0 0.0075 24 0 0 0 9.86E+06 8.65E+06 - - - 9.5573 0.9997 221125_WJC_METTL3_EV_vs_WT_F06.18790.18790.4 0.000146 14/66 K.LKDYAFIHFDER.D "sp|O60506|HNRPQ_HUMAN,tr|A0A7I2YQV8|A0A7I2YQV8_HUMAN,tr|A0A7I2YQN2|A0A7I2YQN2_HUMAN,tr|A0A7I2V4Z0|A0A7I2V4Z0_HUMAN,tr|B7Z645|B7Z645_HUMAN,tr|A0A7I2V2F2|A0A7I2V2F2_HUMAN,tr|A0A7I2V346|A0A7I2V346_HUMAN,tr|A0A7I2V309|A0A7I2V309_HUMAN" 8 1552.7674 1.13 86768 18790 4 1552.768401 389.1991 Heterogeneous nuclear ribonucleoprotein Q OS=Homo sapiens OX=9606 GN=SYNCRIP PE=1 SV=2 5.38 3015.2 - 476161 - - - 0.6266 - 2.352 0.444 - 224.5 1 2 1 0.001 12 0 0 0 7.63E+06 6.74E+06 - - - 3.414 0.9997 221125_WJC_METTL3_EV_vs_WT_F06.18791.18791.3 4.01E-05 13/52 R.VEVERDNLAEDIMR.L "sp|P08670|VIME_HUMAN,tr|B0YJC4|B0YJC4_HUMAN" 2 1687.8199 0.54 86769 18791 3 1687.822053 563.6139 Vimentin OS=Homo sapiens OX=9606 GN=VIM PE=1 SV=4 4.18 3015.3 - 399848 - - - 1.2555 - 2.498 0.449 - 288.4 1 2 1 0.0021 14 0 0 0 1.05E+07 1.93E+07 - - - 5.9783 0.9999 221125_WJC_METTL3_EV_vs_WT_F06.18792.18792.3 4.48E-05 14/84 K.VPEIEVTVEGPNNNNPQTSAVR.T "sp|P78347|GTF2I_HUMAN,tr|A0A494C1K3|A0A494C1K3_HUMAN" 2 2363.1717 1.79 86770 18792 3 2363.179396 788.7312 General transcription factor II-I OS=Homo sapiens OX=9606 GN=GTF2I PE=1 SV=2 4.25 3015.4 - 370962 - - - 3.2494 - 2.709 0.525 - 125.5 1 2 0 0.0077 22 0 0 0 4.55E+09 2.54E+09 - - - 6.7538 0.9999 221125_WJC_METTL3_EV_vs_WT_F06.18796.18796.2 2.07E-07 Nov-38 K.QTQAASASQGSASAAEVLLR[166.11].T "sp|Q969V3|NCLN_HUMAN,tr|K7EMW4|K7EMW4_HUMAN" 2 1954.9948 -1 86774 18796 2 1954.996247 978.5047 Nicalin OS=Homo sapiens OX=9606 GN=NCLN PE=1 SV=2 6 3016 - 0 - - - 0.7647 - 2.289 0.609 - 231.9 1 2 0 0.0015 20 0 0 0 0.00E+00 0.00E+00 - - - 5.5746 1 221125_WJC_METTL3_EV_vs_WT_F06.18798.18798.3 6.05E-11 22/96 K.LVQDVANNTNEEAGDGTTTATVLAR[166.11].S "sp|P10809|CH60_HUMAN,tr|C9JL25|C9JL25_HUMAN,tr|A0A7I2V2X6|A0A7I2V2X6_HUMAN,tr|A0A7I2YQK6|A0A7I2YQK6_HUMAN,tr|A0A7I2V599|A0A7I2V599_HUMAN,tr|E7EXB4|E7EXB4_HUMAN,tr|A0A7I2YQ71|A0A7I2YQ71_HUMAN,tr|E7ESH4|E7ESH4_HUMAN,tr|A0A7I2V5M1|A0A7I2V5M1_HUMAN,tr|A0A7I2V5K3|A0A7I2V5K3_HUMAN,tr|A0A7I2V369|A0A7I2V369_HUMAN" 11 2569.2495 1.78 86775 18798 3 2569.251117 857.4238 "60 kDa heat shock protein, mitochondrial OS=Homo sapiens OX=9606 GN=HSPD1 PE=1 SV=2" 3.92 3016.2 - 533664 - - - 0.6204 - 3.932 0.671 - 640.6 1 2 0 0.0016 25 0 0 0 3.30E+07 1.86E+07 - - - 9.1705 1 221125_WJC_METTL3_EV_vs_WT_F06.18800.18800.3 1.38E-08 19/68 K.SAVDYNTC[160.03]AGVWSQDKWK.G sp|Q9Y5A9|YTHD2_HUMAN 1 2113.9527 1.26 86776 18800 3 2113.957946 705.6582 YTH domain-containing family protein 2 OS=Homo sapiens OX=9606 GN=YTHDF2 PE=1 SV=2 5.68 3016.4 - 2.27E+06 - - - 2.4627 - 3.327 0.657 - 377.4 1 2 1 0.0052 18 0 0 0 8.94E+07 7.10E+07 - - - 8.8567 0.9994 221125_WJC_METTL3_EV_vs_WT_F06.18801.18801.4 0.00112 16/102 K.KFYPLEIDYGQDEEAVKK.L sp|P09874|PARP1_HUMAN 1 2171.0787 1.28 86777 18801 4 2171.088773 543.7769 Poly [ADP-ribose] polymerase 1 OS=Homo sapiens OX=9606 GN=PARP1 PE=1 SV=4 4.51 3016.5 - 1.80E+06 - - - 4.6622 - 2.885 0.452 - 205.4 1 2 0 0.0101 18 0 0 0 1.31E+08 1.03E+08 - - - 3.5204 1 221125_WJC_METTL3_EV_vs_WT_F06.18802.18802.3 6.78E-08 25/84 K.GAVASGHLQESATSVQTALLNR[166.11].L "sp|Q6ULP2|AFTIN_HUMAN,tr|B8ZZI9|B8ZZI9_HUMAN" 2 2219.1534 2.19 86778 18802 3 2219.156753 740.7251 Aftiphilin OS=Homo sapiens OX=9606 GN=AFTPH PE=1 SV=3 6.75 3016.6 - 2.05E+06 - - - 1.5209 - 4.505 0.615 - 730.4 1 2 0 0.0034 22 0 0 0 4.44E+07 2.03E+07 - - - 8.9643 1 221125_WJC_METTL3_EV_vs_WT_F06.18803.18803.4 1.53E-07 25/138 K.K[136.11]AELLDNEK[136.11]PAAVVAPITTGYTVK[136.11].L sp|Q9HB71|CYBP_HUMAN 1 2551.4324 0.5 86779 18803 4 2551.436385 638.8654 Calcyclin-binding protein OS=Homo sapiens OX=9606 GN=CACYBP PE=1 SV=2 6.18 3016.7 - 1.88E+06 - - - 1.5795 - 3.912 0.616 - 385.1 1 2 0 0.004 24 0 0 0 2.07E+07 4.16E+07 - - - 5.0244 0.9254 221125_WJC_METTL3_EV_vs_WT_F06.18804.18804.3 7.96E-07 17/52 K.HWPFQVINDGDK[136.11]PK[136.11].V "sp|P0DMV8|HS71A_HUMAN,sp|P0DMV9|HS71B_HUMAN,tr|A0A0G2JIW1|A0A0G2JIW1_HUMAN" 3 1695.8704 0.24 86780 18804 3 1696.859863 566.2974 Heat shock 70 kDa protein 1A OS=Homo sapiens OX=9606 GN=HSPA1A PE=1 SV=1 6.75 3016.8 - 1.15E+06 - - - 583.4603 - 2.748 0.525 - 458.3 1 2 0 0.9895 14 0 0 0 1.63E+06 6.76E+06 - - - 6.8056 0.9998 221125_WJC_METTL3_EV_vs_WT_F06.18811.18811.4 8.47E-07 13/78 K.DKFSFDLGKGEVIK.A "sp|Q02790|FKBP4_HUMAN,tr|F5H1U3|F5H1U3_HUMAN" 2 1581.8403 1.02 86787 18811 4 1581.84285 396.4673 Peptidyl-prolyl cis-trans isomerase FKBP4 OS=Homo sapiens OX=9606 GN=FKBP4 PE=1 SV=3 6.12 3017.6 - 322141 - - - 1.638 - 2.039 0.524 - 89.1 1 2 2 0.0026 14 0 0 0 2.57E+06 2.50E+06 - - - 4.0455 0.9993 221125_WJC_METTL3_EV_vs_WT_F06.18813.18813.3 0.00104 Jul-76 R.FSSC[160.03]GGGGGSFGAGGGFGSR.S sp|P04264|K2C1_HUMAN 1 1764.7274 1.4 86789 18813 3 1764.733039 589.2498 "Keratin, type II cytoskeletal 1 OS=Homo sapiens OX=9606 GN=KRT1 PE=1 SV=6" 8.25 3017.9 - 190286 - - - 3.1778 - 1.63 0.449 - 28.8 1 2 0 0.0056 20 0 0 0 6.44E+06 4.61E+06 - - - 4.7297 1 221125_WJC_METTL3_EV_vs_WT_F06.18816.18816.4 1.05E-12 21/102 K.K[136.11]FYPLEIDYGQDEEAVK[136.11]K[136.11].L sp|P09874|PARP1_HUMAN 1 2195.1213 1.73 86790 18816 4 2195.128657 549.7876 Poly [ADP-ribose] polymerase 1 OS=Homo sapiens OX=9606 GN=PARP1 PE=1 SV=4 4.51 3018.3 - 3.27E+06 - - - 3.3738 - 3.656 0.668 - 464.3 1 2 0 0.0074 18 0 0 0 2.16E+08 1.25E+08 - - - 5.4823 1 221125_WJC_METTL3_EV_vs_WT_F06.18818.18818.4 3.99E-06 13/108 R.GLLQDDAHPTLVTYADHSK[136.11].L "sp|Q86U44|MTA70_HUMAN,tr|F5H6D8|F5H6D8_HUMAN,tr|H0YFV6|H0YFV6_HUMAN,tr|B4DTN4|B4DTN4_HUMAN" 4 2088.0367 0.02 86792 18818 4 2088.040347 523.0165 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 5.13 3018.4 - 3.96E+06 - - - 1.7308 - 2.841 0.559 - 160.4 1 2 0 0.0036 19 0 0 0 1.81E+06 7.30E+07 - - - 4.4438 1 221125_WJC_METTL3_EV_vs_WT_F06.18821.18821.4 4.11E-07 22/138 K.KAELLDNEKPAAVVAPITTGYTVK.L sp|Q9HB71|CYBP_HUMAN 1 2527.3898 0.5 86795 18821 4 2527.396086 632.8547 Calcyclin-binding protein OS=Homo sapiens OX=9606 GN=CACYBP PE=1 SV=2 6.18 3018.7 - 1.70E+06 - - - 2.505 - 3.602 0.573 - 306.2 1 2 0 0.0063 24 0 0 0 2.07E+07 4.16E+07 - - - 4.623 1 221125_WJC_METTL3_EV_vs_WT_F06.18823.18823.3 1.39E-06 28/92 K.K[136.11]AELLDNEK[136.11]PAAVVAPITTGYTVK[136.11].L sp|Q9HB71|CYBP_HUMAN 1 2551.4324 0.37 86797 18823 3 2551.434929 851.4847 Calcyclin-binding protein OS=Homo sapiens OX=9606 GN=CACYBP PE=1 SV=2 6.18 3018.9 - 680934 - - - 1.0088 - 4.084 0.614 - 686.3 1 2 0 0.0026 24 0 0 0 3.26E+06 8.82E+06 - - - 8.6529 1 221125_WJC_METTL3_EV_vs_WT_F06.18824.18824.3 8.40E-20 24/92 R.GDVASC[160.03]NTQVAEK[136.11]PVLTAVPGITR[166.11].H "sp|O75152|ZC11A_HUMAN,tr|E9PQ61|E9PQ61_HUMAN" 2 2500.3074 1.14 86798 18824 3 2500.308727 834.4431 Zinc finger CCCH domain-containing protein 11A OS=Homo sapiens OX=9606 GN=ZC3H11A PE=1 SV=3 6.06 3019.1 - 673441 - - - 0.5135 - 4.266 0.774 - 474.8 1 2 0 0.0013 24 0 0 0 9.86E+06 8.65E+06 - - - 10.5383 0.9999 221125_WJC_METTL3_EV_vs_WT_F06.18825.18825.3 1.50E-06 14/64 K.R[166.11]EDGGYTFTATPEDFPK[136.11].K "sp|Q9Y4P3|TBL2_HUMAN,tr|E9PF19|E9PF19_HUMAN,tr|Q96E41|Q96E41_HUMAN,tr|A0A087WXC6|A0A087WXC6_HUMAN" 4 1947.8969 0.84 86799 18825 3 1947.894793 650.3063 Transducin beta-like protein 2 OS=Homo sapiens OX=9606 GN=TBL2 PE=1 SV=1 4.32 3019.2 - 646499 - - - -1.1032 - 2.67 0.44 - 258.9 1 2 0 -0.0021 17 0 0 0 8.08E+06 9.57E+06 - - - 5.926 0.9349 221125_WJC_METTL3_EV_vs_WT_F06.18827.18827.4 0.000204 Dec-84 A.SDLELHPPSYPWSHR.G sp|P08574|CY1_HUMAN 1 1819.8642 1.36 86801 18827 4 1819.867897 455.9733 "Cytochrome c1, heme protein, mitochondrial OS=Homo sapiens OX=9606 GN=CYC1 PE=1 SV=3" 5.94 3019.4 - 374233 - - - 2.0414 - 2.509 0.34 - 133.4 1 1 0 0.0037 15 0 0 0 1.62E+07 1.19E+07 - - - 2.5135 1 221125_WJC_METTL3_EV_vs_WT_F06.18829.18829.3 3.49E-11 21/92 K.KAELLDNEKPAAVVAPITTGYTVK.L sp|Q9HB71|CYBP_HUMAN 1 2527.3898 0.37 86803 18829 3 2527.388094 843.4705 Calcyclin-binding protein OS=Homo sapiens OX=9606 GN=CACYBP PE=1 SV=2 6.18 3019.7 - 355402 - - - -0.6572 - 4.011 0.654 - 400.2 1 2 0 -0.0017 24 0 0 0 3.26E+06 8.82E+06 - - - 9.0572 1 221125_WJC_METTL3_EV_vs_WT_F06.18835.18835.3 1.44E-14 23/68 K.SAVDYNTC[160.03]AGVWSQDK[136.11]WK[136.11].G sp|Q9Y5A9|YTHD2_HUMAN 1 2129.9811 1.26 86808 18835 3 2129.984782 711.001 YTH domain-containing family protein 2 OS=Homo sapiens OX=9606 GN=YTHDF2 PE=1 SV=2 5.68 3020.4 - 6.90E+06 - - - 1.7099 - 4.58 0.72 - 732.9 1 2 1 0.0036 18 0 0 0 8.97E+07 7.10E+07 - - - 10.3555 0.9832 221125_WJC_METTL3_EV_vs_WT_F06.18841.18841.4 0.00563 13/72 K.LKDLFDYSPPLHK.N "sp|Q9NYF8|BCLF1_HUMAN,tr|E9PKI6|E9PKI6_HUMAN,tr|A0A1W2PQ43|A0A1W2PQ43_HUMAN,tr|E9PK91|E9PK91_HUMAN,tr|E9PK09|E9PK09_HUMAN,tr|E9PQN2|E9PQN2_HUMAN" 6 1571.8348 2.26 86814 18841 4 1571.837929 393.966 Bcl-2-associated transcription factor 1 OS=Homo sapiens OX=9606 GN=BCLAF1 PE=1 SV=2 6.75 3021 - 489336 - - - 2.0034 - 1.433 0.263 - 86.8 1 2 1 0.0031 13 0 0 0 9.42E+07 4.18E+07 - - - 1.6477 0.9805 221125_WJC_METTL3_EV_vs_WT_F06.18842.18842.4 0.000871 Nov-84 A.SDLELHPPSYPWSHR[166.11].G sp|P08574|CY1_HUMAN 1 1829.8725 1.35 86815 18842 4 1829.875751 458.4754 "Cytochrome c1, heme protein, mitochondrial OS=Homo sapiens OX=9606 GN=CYC1 PE=1 SV=3" 5.94 3021.1 - 384928 - - - 1.8029 - 2.245 0.411 - 96.1 1 1 0 0.0033 15 0 0 0 1.56E+07 1.16E+07 - - - 3.0918 0.9998 221125_WJC_METTL3_EV_vs_WT_F06.18849.18849.4 8.42E-07 18/132 R.LVPGRHDIAFVEFENDGQAGAAR.D sp|P08579|RU2B_HUMAN 1 2468.2197 0.41 86820 18849 4 2468.224524 618.0622 U2 small nuclear ribonucleoprotein B'' OS=Homo sapiens OX=9606 GN=SNRPB2 PE=1 SV=1 4.75 3022 - 734682 - - - 1.9666 - 3.045 0.489 - 199.5 1 2 1 0.0049 23 0 0 0 9.68E+06 2.36E+07 - - - 3.8417 0.9981 221125_WJC_METTL3_EV_vs_WT_F06.18860.18860.3 0.000229 Nov-76 K.DIFAMDDK[136.11]SENEPIENEAAK[136.11].Y "sp|Q96I99|SUCB2_HUMAN,tr|E9PDQ8|E9PDQ8_HUMAN" 2 2281.0391 0.92 86829 18860 3 2281.040044 761.3536 "Succinate--CoA ligase [GDP-forming] subunit beta, mitochondrial OS=Homo sapiens OX=9606 GN=SUCLG2 PE=1 SV=2" 3.95 3023.4 - 337707 - - - 0.4103 - 2.152 0.321 - 76.3 1 2 1 0.0009 20 0 0 0 7.97E+06 8.62E+06 - - - 3.9779 0.9997 221125_WJC_METTL3_EV_vs_WT_F06.18863.18863.3 3.63E-07 21/88 K.ASPEAASTPRDPIDVDLPEEAER.V "sp|P29590|PML_HUMAN,tr|H3BT29|H3BT29_HUMAN,tr|H3BVD2|H3BVD2_HUMAN" 3 2464.1718 1.9 86832 18863 3 2464.1808 822.3979 Protein PML OS=Homo sapiens OX=9606 GN=PML PE=1 SV=3 3.95 3023.8 - 396307 - - - 3.6617 - 3.699 0.563 - 452.6 1 2 1 0.009 23 0 0 0 6.51E+06 3.43E+06 - - - 7.883 1 221125_WJC_METTL3_EV_vs_WT_F06.18870.18870.3 1.96E-11 21/76 K.DIFAMDDKSENEPIENEAAK.Y "sp|Q96I99|SUCB2_HUMAN,tr|E9PDQ8|E9PDQ8_HUMAN" 2 2265.0107 0.84 86837 18870 3 2265.015263 756.0108 "Succinate--CoA ligase [GDP-forming] subunit beta, mitochondrial OS=Homo sapiens OX=9606 GN=SUCLG2 PE=1 SV=2" 3.95 3024.7 - 528305 - - - 2.011 - 3.818 0.698 - 395.3 1 2 1 0.0046 20 0 0 0 7.97E+06 9.48E+06 - - - 9.571 0.9996 221125_WJC_METTL3_EV_vs_WT_F06.18873.18873.3 0.00402 Sep-72 K.WSSSPENAC[160.03]GLPSPISTNR.Q "sp|Q8IWC1|MA7D3_HUMAN,tr|A0A0A0MRP0|A0A0A0MRP0_HUMAN" 2 2058.9429 1.57 86840 18873 3 2058.939614 687.3216 MAP7 domain-containing protein 3 OS=Homo sapiens OX=9606 GN=MAP7D3 PE=1 SV=2 5.99 3025.1 - 296301 - - - -1.5974 - 1.856 0.378 - 49.7 1 2 0 -0.0033 19 0 0 0 7.46E+06 4.74E+06 - - - 4.2728 1 221125_WJC_METTL3_EV_vs_WT_F06.18879.18879.4 0.000289 14/78 K.AVDIPHMDIEALK[136.11]K[136.11].L sp|P62906|RL10A_HUMAN 1 1594.8724 1.03 86844 18879 4 1594.874506 399.7254 60S ribosomal protein L10a OS=Homo sapiens OX=9606 GN=RPL10A PE=1 SV=2 5.38 3025.9 - 689153 - - - 1.3431 - 2.501 0.526 - 128.2 1 2 0 0.0021 14 0 0 0 9.95E+07 9.65E+07 - - - 4.1373 0.9999 221125_WJC_METTL3_EV_vs_WT_F06.18880.18880.3 2.03E-07 19/88 R.GLQLGQTSTATIQPSQQAQIVTR.S "sp|O94842|TOX4_HUMAN,tr|A0A669KB71|A0A669KB71_HUMAN" 2 2425.2925 1.95 86845 18880 3 2425.299724 809.4381 TOX high mobility group box family member 4 OS=Homo sapiens OX=9606 GN=TOX4 PE=1 SV=1 9.75 3026.1 - 608655 - - - 2.9782 - 3.636 0.548 - 315.2 1 2 0 0.0072 23 0 0 0 2.14E+07 1.10E+07 - - - 7.676 0.9997 221125_WJC_METTL3_EV_vs_WT_F06.18881.18881.3 2.53E-06 18/88 R.GLQLGQTSTATIQPSQQAQIVTR[166.11].S "sp|O94842|TOX4_HUMAN,tr|A0A669KB71|A0A669KB71_HUMAN" 2 2435.3008 1.95 86846 18881 3 2435.313105 812.7742 TOX high mobility group box family member 4 OS=Homo sapiens OX=9606 GN=TOX4 PE=1 SV=1 9.75 3026.2 - 365298 - - - 5.0647 - 3.555 0.531 - 274.1 1 2 0 0.0123 23 0 0 0 2.14E+07 1.10E+07 - - - 7.4322 0.9899 221125_WJC_METTL3_EV_vs_WT_F06.18887.18887.3 0.0308 Sep-52 R.QNKPENWDVWYESK.F "sp|Q8NDZ4|DIK2A_HUMAN,tr|E7ET39|E7ET39_HUMAN,tr|C9JY09|C9JY09_HUMAN" 3 1821.8322 11.07 86851 18887 3 1821.828112 608.2847 Divergent protein kinase domain 2A OS=Homo sapiens OX=9606 GN=DIPK2A PE=1 SV=1 4.68 3026.9 - 934492 - - - -2.251 - 1.858 0.187 - 104.5 1 2 0 -0.0041 14 0 0 0 1.91E+07 1.73E+06 - - - 2.2701 0.9997 221125_WJC_METTL3_EV_vs_WT_F06.18889.18889.4 9.12E-07 19/120 R.QLFHPEQLITGKEDAANNYAR.G "sp|Q9NY65|TBA8_HUMAN,sp|P0DPH7|TBA3C_HUMAN,sp|Q71U36|TBA1A_HUMAN,sp|P0DPH8|TBA3D_HUMAN,sp|P68366|TBA4A_HUMAN,sp|P68363|TBA1B_HUMAN,sp|Q9BQE3|TBA1C_HUMAN,tr|C9JJQ8|C9JJQ8_HUMAN,tr|F8VS66|F8VS66_HUMAN,tr|F8VWV9|F8VWV9_HUMAN,tr|F8VRZ4|F8VRZ4_HUMAN,tr|F8VVB9|F8VVB9_HUMAN,tr|C9JQ00|C9JQ00_HUMAN,tr|C9JEV8|C9JEV8_HUMAN,tr|A0A7P0TA31|A0A7P0TA31_HUMAN,tr|A0A1W2PQM2|A0A1W2PQM2_HUMAN,tr|F5H5D3|F5H5D3_HUMAN,tr|C9J2C0|C9J2C0_HUMAN,tr|C9K0S6|C9K0S6_HUMAN,tr|C9JDL2|C9JDL2_HUMAN,tr|F8VQQ4|F8VQQ4_HUMAN,tr|F8VX09|F8VX09_HUMAN,tr|A0A7P0T945|A0A7P0T945_HUMAN" 23 2414.1979 0.65 86853 18889 4 2414.205249 604.5567 Tubulin alpha-8 chain OS=Homo sapiens OX=9606 GN=TUBA8 PE=1 SV=1 5.45 3027.1 - 605933 - - - 3.0557 - 3.933 0.529 - 286.4 1 2 1 0.0074 21 0 0 0 5.42E+06 8.40E+06 - - - 4.2812 1 221125_WJC_METTL3_EV_vs_WT_F06.18891.18891.3 4.79E-13 22/108 K.APEPVC[160.03]AAPGPPHGPAGAASNFYSAVGR[166.11].N sp|P31277|HXD11_HUMAN 1 2714.2899 3.67 86855 18891 3 2714.294705 905.7706 Homeobox protein Hox-D11 OS=Homo sapiens OX=9606 GN=HOXD11 PE=3 SV=3 6.78 3027.4 - 343013 - - - 1.7743 - 3.728 0.65 - 277.9 1 2 0 0.0048 28 0 0 0 2.94E+07 8.00E+06 - - - 8.8129 0.9997 221125_WJC_METTL3_EV_vs_WT_F06.18892.18892.2 2.48E-09 Nov-36 K.WSSSPENAC[160.03]GLPSPISTNR.Q "sp|Q8IWC1|MA7D3_HUMAN,tr|A0A0A0MRP0|A0A0A0MRP0_HUMAN" 2 2058.9429 2.9 86856 18892 2 2058.948562 1030.4787 MAP7 domain-containing protein 3 OS=Homo sapiens OX=9606 GN=MAP7D3 PE=1 SV=2 5.99 3027.5 - 155188 - - - 2.7485 - 2.463 0.589 - 195.4 1 2 0 0.0057 19 0 0 0 3.46E+06 1.19E+06 - - - 5.6057 0.9874 221125_WJC_METTL3_EV_vs_WT_F06.18893.18893.2 2.03E-06 Oct-34 N.SASSSNPPAEVDPDTILK.A "sp|Q9BY77|PDIP3_HUMAN,tr|F6VRR5|F6VRR5_HUMAN" 2 1826.8898 2.14 86857 18893 2 1826.886678 914.4522 Polymerase delta-interacting protein 3 OS=Homo sapiens OX=9606 GN=POLDIP3 PE=1 SV=2 4.03 3027.6 - 103481 - - - -1.7023 - 1.963 0.564 - 211.3 1 1 0 -0.0031 18 0 0 0 2.24E+07 1.05E+07 - - - 4.864 1 221125_WJC_METTL3_EV_vs_WT_F06.18898.18898.3 9.75E-11 17/68 K.YVHYEIDAC[160.03]MDSEAPGSK[136.11].D "sp|Q86U44|MTA70_HUMAN,tr|H0YFV6|H0YFV6_HUMAN" 2 2078.8805 0 86860 18898 3 2079.886918 693.9674 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 4.31 3028.2 - 3.14E+06 - - - 484.1192 - 3.504 0.693 - 304.4 1 2 0 1.0064 18 0 0 0 1.99E+05 7.20E+07 - - - 9.1098 0.9999 221125_WJC_METTL3_EV_vs_WT_F06.18899.18899.4 1.67E-06 18/102 R.K[136.11]PYVLNDLEAEASLPEK[136.11]K[136.11].G "sp|Q9Y3C1|NOP16_HUMAN,tr|A0A0C4DGU5|A0A0C4DGU5_HUMAN,tr|D6RIC3|D6RIC3_HUMAN,tr|A0A087X2G6|A0A087X2G6_HUMAN" 4 2067.1314 1.34 86861 18899 4 2067.136577 517.7901 Nucleolar protein 16 OS=Homo sapiens OX=9606 GN=NOP16 PE=1 SV=2 4.87 3028.3 - 507183 - - - 2.4938 - 3.3 0.518 - 260.7 1 2 0 0.0052 18 0 0 0 2.22E+07 1.66E+07 - - - 4.1422 0.994 221125_WJC_METTL3_EV_vs_WT_F06.18900.18900.4 0.00135 Sep-78 R.LKQEFHYIEEDLYR.T sp|Q8TBA6|GOGA5_HUMAN 1 1881.9261 1.85 86862 18900 4 1881.930509 471.4888 Golgin subfamily A member 5 OS=Homo sapiens OX=9606 GN=GOLGA5 PE=1 SV=3 4.83 3028.5 - 314153 - - - 2.3354 - 1.881 0.311 - 68 1 2 1 0.0044 14 0 0 0 2.83E+06 1.54E+06 - - - 2.1617 0.9999 221125_WJC_METTL3_EV_vs_WT_F06.18901.18901.2 5.72E-07 13/36 K.WSSSPENAC[160.03]GLPSPISTNR[166.11].Q "sp|Q8IWC1|MA7D3_HUMAN,tr|A0A0A0MRP0|A0A0A0MRP0_HUMAN" 2 2068.9512 2.82 86863 18901 2 2068.95437 1035.4829 MAP7 domain-containing protein 3 OS=Homo sapiens OX=9606 GN=MAP7D3 PE=1 SV=2 5.99 3028.6 - 180958 - - - 1.5452 - 2.511 0.584 - 303 1 2 0 0.0032 19 0 0 0 3.36E+06 1.19E+06 - - - 5.617 1 221125_WJC_METTL3_EV_vs_WT_F06.18906.18906.4 0.000437 15/78 K.AVDIPHMDIEALKK.L sp|P62906|RL10A_HUMAN 1 1578.844 1.02 86866 18906 4 1578.845176 395.7183 60S ribosomal protein L10a OS=Homo sapiens OX=9606 GN=RPL10A PE=1 SV=2 5.38 3029.1 - 1.25E+06 - - - 0.7677 - 2.585 0.5 - 115.3 1 2 0 0.0012 14 0 0 0 1.00E+08 9.81E+07 - - - 3.9233 0.9999 221125_WJC_METTL3_EV_vs_WT_F06.18909.18909.3 6.12E-05 18/72 R.EGR[166.11]PSGEAFVELESEEEVK[136.11].L sp|P55795|HNRH2_HUMAN 1 2138.0134 1.03 86869 18909 3 2138.020359 713.6784 Heterogeneous nuclear ribonucleoprotein H2 OS=Homo sapiens OX=9606 GN=HNRNPH2 PE=1 SV=1 4.12 3029.5 - 518493 - - - 3.2413 - 3.909 0.53 - 435.7 1 2 0 0.0069 19 0 0 0 1.02E+07 9.96E+06 - - - 7.7964 0.998 221125_WJC_METTL3_EV_vs_WT_F06.18913.18913.4 0.0315 13/84 R.ETITAPVPFDFTHK[136.11]K[136.11].Q "sp|Q96RP9|EFGM_HUMAN,tr|C9IZ01|C9IZ01_HUMAN" 2 1745.9323 0.28 86873 18913 4 1745.934561 437.4904 "Elongation factor G, mitochondrial OS=Homo sapiens OX=9606 GN=GFM1 PE=1 SV=2" 6.85 3030 - 213883 - - - 1.2824 - 2.219 0.261 - 175 1 2 0 0.0022 15 0 0 0 2.14E+06 7.67E+06 - - - 1.7823 0.9948 221125_WJC_METTL3_EV_vs_WT_F06.18914.18914.3 0.00957 13/52 K.KGGSFQLNELQGLK.S "sp|P02788|TRFL_HUMAN,tr|C9JCF5|C9JCF5_HUMAN,tr|E7EQB2|E7EQB2_HUMAN,tr|E7ER44|E7ER44_HUMAN" 4 1517.8202 52.51 86874 18914 3 1517.830501 506.9473 Lactotransferrin OS=Homo sapiens OX=9606 GN=LTF PE=1 SV=6 8.59 3030.2 - 203189 - - - 6.792 - 2.482 0.38 - 193.4 1 2 0 0.0103 14 0 0 0 3.12E+06 5.94E+04 - - - 5.1896 0.9991 221125_WJC_METTL3_EV_vs_WT_F06.18918.18918.4 0.000153 15/120 R.QLFHPEQLITGK[136.11]EDAANNYAR[166.11].G "sp|Q9NY65|TBA8_HUMAN,sp|P0DPH7|TBA3C_HUMAN,sp|Q71U36|TBA1A_HUMAN,sp|P0DPH8|TBA3D_HUMAN,sp|P68366|TBA4A_HUMAN,sp|P68363|TBA1B_HUMAN,sp|Q9BQE3|TBA1C_HUMAN,tr|C9JJQ8|C9JJQ8_HUMAN,tr|F8VS66|F8VS66_HUMAN,tr|F8VWV9|F8VWV9_HUMAN,tr|F8VRZ4|F8VRZ4_HUMAN,tr|F8VVB9|F8VVB9_HUMAN,tr|C9JQ00|C9JQ00_HUMAN,tr|C9JEV8|C9JEV8_HUMAN,tr|A0A7P0TA31|A0A7P0TA31_HUMAN,tr|A0A1W2PQM2|A0A1W2PQM2_HUMAN,tr|F5H5D3|F5H5D3_HUMAN,tr|C9J2C0|C9J2C0_HUMAN,tr|C9K0S6|C9K0S6_HUMAN,tr|C9JDL2|C9JDL2_HUMAN,tr|F8VQQ4|F8VQQ4_HUMAN,tr|F8VX09|F8VX09_HUMAN,tr|A0A7P0T945|A0A7P0T945_HUMAN" 23 2432.2203 1.03 86876 18918 4 2432.224675 609.0624 Tubulin alpha-8 chain OS=Homo sapiens OX=9606 GN=TUBA8 PE=1 SV=1 5.45 3030.7 - 715477 - - - 1.7815 - 3.157 0.381 - 207.9 1 2 1 0.0043 21 0 0 0 1.58E+07 1.53E+07 - - - 2.9211 1 221125_WJC_METTL3_EV_vs_WT_F06.18921.18921.3 1.35E-09 19/68 R.KPYVLNDLEAEASLPEKK.G "sp|Q9Y3C1|NOP16_HUMAN,tr|A0A0C4DGU5|A0A0C4DGU5_HUMAN,tr|D6RIC3|D6RIC3_HUMAN,tr|A0A087X2G6|A0A087X2G6_HUMAN" 4 2043.0888 1.12 86879 18921 3 2043.09212 682.0369 Nucleolar protein 16 OS=Homo sapiens OX=9606 GN=NOP16 PE=1 SV=2 4.87 3031.1 - 606248 - - - 1.6142 - 3.264 0.575 - 388.7 1 2 0 0.0033 18 0 0 0 1.57E+07 1.40E+07 - - - 7.8954 1 221125_WJC_METTL3_EV_vs_WT_F06.18922.18922.3 6.66E-09 16/80 K.FC[160.03]NIMGSSNGVDQEHFSNVVK[136.11].G "sp|Q9NYL9|TMOD3_HUMAN,tr|H0YNJ8|H0YNJ8_HUMAN" 2 2376.0718 1.18 86880 18922 3 2376.07412 793.0312 Tropomodulin-3 OS=Homo sapiens OX=9606 GN=TMOD3 PE=1 SV=1 5.32 3031.2 - 514063 - - - 0.9701 - 3.023 0.695 - 221.9 1 2 0 0.0023 21 0 0 0 6.15E+06 5.23E+06 - - - 8.9401 1 221125_WJC_METTL3_EV_vs_WT_F06.18924.18924.3 1.44E-05 17/68 R.K[136.11]PYVLNDLEAEASLPEK[136.11]K[136.11].G "sp|Q9Y3C1|NOP16_HUMAN,tr|A0A0C4DGU5|A0A0C4DGU5_HUMAN,tr|D6RIC3|D6RIC3_HUMAN,tr|A0A087X2G6|A0A087X2G6_HUMAN" 4 2067.1314 1.12 86882 18924 3 2067.133075 690.0511 Nucleolar protein 16 OS=Homo sapiens OX=9606 GN=NOP16 PE=1 SV=2 4.87 3031.5 - 417680 - - - 0.7997 - 3.158 0.491 - 278.8 1 2 0 0.0017 18 0 0 0 1.57E+07 1.40E+07 - - - 6.8772 0.9999 221125_WJC_METTL3_EV_vs_WT_F06.18925.18925.4 2.77E-05 15/90 K.K[136.11]IHTEPQLSAALEYVR[166.11].S "sp|P47897|SYQ_HUMAN,tr|A0A0U1RQL2|A0A0U1RQL2_HUMAN,tr|A0A0U1RRI9|A0A0U1RRI9_HUMAN,tr|A0A0U1RQT0|A0A0U1RQT0_HUMAN,tr|A0A1B0GVU9|A0A1B0GVU9_HUMAN,tr|A0A0U1RQE9|A0A0U1RQE9_HUMAN,tr|A0A0U1RQM8|A0A0U1RQM8_HUMAN,tr|A0A0U1RQU2|A0A0U1RQU2_HUMAN" 8 1872.0224 1.72 86883 18925 4 1872.02428 469.0129 Glutamine--tRNA ligase OS=Homo sapiens OX=9606 GN=QARS1 PE=1 SV=1 6.76 3031.6 - 341587 - - - 0.9952 - 2.587 0.402 - 202.4 1 2 0 0.0019 16 0 0 0 1.35E+07 7.84E+06 - - - 3.0593 0.9024 221125_WJC_METTL3_EV_vs_WT_F06.18938.18938.3 8.45E-08 14/100 R.ISSVLAGGSC[160.03]RAPSTYGGGLSVSSSR.F sp|P02533|K1C14_HUMAN 1 2512.234 0.63 86894 18938 3 2513.223905 838.4186 "Keratin, type I cytoskeletal 14 OS=Homo sapiens OX=9606 GN=KRT14 PE=1 SV=4" 9.5 3033.3 - 370002 - - - 394.0338 - 3.075 0.478 - 132.6 1 2 1 0.9899 26 0 0 0 1.40E+06 2.24E+06 - - - 6.1793 0.9932 221125_WJC_METTL3_EV_vs_WT_F06.18940.18940.3 0.000161 10/100 K.VDKGVVPLAGTNGETTTQGLDGLSER.C "sp|P04075|ALDOA_HUMAN,tr|H3BR04|H3BR04_HUMAN,tr|H3BMQ8|H3BMQ8_HUMAN,tr|H3BU78|H3BU78_HUMAN,tr|H3BQN4|H3BQN4_HUMAN,tr|H3BUH7|H3BUH7_HUMAN,tr|J3KPS3|J3KPS3_HUMAN,tr|H3BPS8|H3BPS8_HUMAN" 8 2613.3246 2.33 86896 18940 3 2613.340522 872.1155 Fructose-bisphosphate aldolase A OS=Homo sapiens OX=9606 GN=ALDOA PE=1 SV=2 4.32 3033.5 - 247409 - - - 6.0968 - 2.475 0.49 - 81.7 1 2 1 0.0159 26 0 0 0 7.43E+06 3.19E+06 - - - 6.0835 0.9908 221125_WJC_METTL3_EV_vs_WT_F06.18944.18944.4 1.50E-07 15/120 R.TSPFLTHQVFNSYHSETNIVR[166.11].Y sp|P23378|GCSP_HUMAN 1 2486.2218 0.22 86898 18944 4 2487.230755 622.5627 "Glycine dehydrogenase (decarboxylating), mitochondrial OS=Homo sapiens OX=9606 GN=GLDC PE=1 SV=2" 6.61 3034.1 - 1.42E+06 - - - 405.8218 - 3.343 0.413 - 144.1 1 2 0 1.009 21 0 0 0 7.22E+06 3.24E+07 - - - 2.9403 0.999 221125_WJC_METTL3_EV_vs_WT_F06.18947.18947.3 0.000852 Oct-60 R.DLVGMGHHFLPSEPTK.W "sp|Q8IXK0|PHC2_HUMAN,tr|A0A0A0MSI2|A0A0A0MSI2_HUMAN,tr|B3KPJ4|B3KPJ4_HUMAN" 3 1763.8665 2.26 86901 18947 3 1763.869694 588.9628 Polyhomeotic-like protein 2 OS=Homo sapiens OX=9606 GN=PHC2 PE=1 SV=1 5.99 3034.4 - 532206 - - - 1.8165 - 1.783 0.329 - 70.8 1 2 0 0.0032 16 0 0 0 1.16E+07 5.10E+06 - - - 3.691 0.9987 221125_WJC_METTL3_EV_vs_WT_F06.18949.18949.4 0.0153 Nov-90 R.DLVGMGHHFLPSEPTK.W "sp|Q8IXK0|PHC2_HUMAN,tr|A0A0A0MSI2|A0A0A0MSI2_HUMAN,tr|B3KPJ4|B3KPJ4_HUMAN" 3 1763.8665 1.79 86903 18949 4 1763.86823 441.9739 Polyhomeotic-like protein 2 OS=Homo sapiens OX=9606 GN=PHC2 PE=1 SV=1 5.99 3034.7 - 276469 - - - 0.9865 - 1.799 0.287 - 56.8 1 2 0 0.0017 16 0 0 0 6.25E+06 3.50E+06 - - - 1.9304 1 221125_WJC_METTL3_EV_vs_WT_F06.18953.18953.4 2.42E-10 20/102 R.KPYVLNDLEAEASLPEKK.G "sp|Q9Y3C1|NOP16_HUMAN,tr|A0A0C4DGU5|A0A0C4DGU5_HUMAN,tr|D6RIC3|D6RIC3_HUMAN,tr|A0A087X2G6|A0A087X2G6_HUMAN" 4 2043.0888 1.35 86906 18953 4 2043.093994 511.7795 Nucleolar protein 16 OS=Homo sapiens OX=9606 GN=NOP16 PE=1 SV=2 4.87 3035.1 - 1.55E+06 - - - 2.5315 - 3.736 0.595 - 316.3 1 2 0 0.0052 18 0 0 0 2.24E+07 1.66E+07 - - - 4.8549 1 221125_WJC_METTL3_EV_vs_WT_F06.18954.18954.3 2.99E-07 18/80 R.FVEGVC[160.03]PFC[160.03]GYEEAR[166.11]GDQC[160.03]DK[136.11].C "sp|P56192|SYMC_HUMAN,tr|H0YIC2|H0YIC2_HUMAN" 2 2540.0526 0.98 86907 18954 3 2540.054881 847.6915 "Methionine--tRNA ligase, cytoplasmic OS=Homo sapiens OX=9606 GN=MARS1 PE=1 SV=2" 4.18 3035.2 - 764833 - - - 0.9173 - 3.636 0.64 - 238.9 1 2 1 0.0023 21 0 0 0 1.21E+07 1.23E+07 - - - 8.7696 1 221125_WJC_METTL3_EV_vs_WT_F06.18955.18955.3 8.55E-10 22/80 R.FVEGVC[160.03]PFC[160.03]GYEEARGDQC[160.03]DK.C "sp|P56192|SYMC_HUMAN,tr|H0YIC2|H0YIC2_HUMAN" 2 2522.0301 0.98 86908 18955 3 2522.028945 841.684 "Methionine--tRNA ligase, cytoplasmic OS=Homo sapiens OX=9606 GN=MARS1 PE=1 SV=2" 4.18 3035.4 - 703540 - - - -0.4504 - 4.148 0.75 - 439 1 2 1 -0.0011 21 0 0 0 1.21E+07 1.23E+07 - - - 10.3121 0.9996 221125_WJC_METTL3_EV_vs_WT_F06.18962.18962.3 7.04E-09 18/60 K.K[136.11]IHTEPQLSAALEYVR[166.11].S "sp|P47897|SYQ_HUMAN,tr|A0A0U1RQL2|A0A0U1RQL2_HUMAN,tr|A0A0U1RRI9|A0A0U1RRI9_HUMAN,tr|A0A0U1RQT0|A0A0U1RQT0_HUMAN,tr|A0A1B0GVU9|A0A1B0GVU9_HUMAN,tr|A0A0U1RQE9|A0A0U1RQE9_HUMAN,tr|A0A0U1RQM8|A0A0U1RQM8_HUMAN,tr|A0A0U1RQU2|A0A0U1RQU2_HUMAN" 8 1872.0224 1.75 86913 18962 3 1872.02963 625.0147 Glutamine--tRNA ligase OS=Homo sapiens OX=9606 GN=QARS1 PE=1 SV=1 6.76 3036.3 - 568108 - - - 3.8531 - 3.179 0.396 - 508.5 1 2 0 0.0072 16 0 0 0 1.38E+07 7.89E+06 - - - 5.9206 1 221125_WJC_METTL3_EV_vs_WT_F06.18963.18963.3 2.43E-10 16/76 K.VHSPSGALEEC[160.03]YVTEIDQDK.Y "sp|P21333|FLNA_HUMAN,tr|A0A7P0NMY4|A0A7P0NMY4_HUMAN,tr|Q60FE5|Q60FE5_HUMAN" 3 2276.0267 1.11 86914 18963 3 2276.023387 759.6828 Filamin-A OS=Homo sapiens OX=9606 GN=FLNA PE=1 SV=4 4.17 3036.4 - 640534 - - - -1.4521 - 3.291 0.519 - 363.1 1 2 0 -0.0033 20 0 0 0 8.56E+06 7.69E+06 - - - 7.2153 0.9178 221125_WJC_METTL3_EV_vs_WT_F06.18965.18965.2 1.88E-07 Dec-34 N.SASSSNPPAEVDPDTILK[136.11].A "sp|Q9BY77|PDIP3_HUMAN,tr|F6VRR5|F6VRR5_HUMAN" 2 1834.904 2.14 86916 18965 2 1834.912694 918.4593 Polymerase delta-interacting protein 3 OS=Homo sapiens OX=9606 GN=POLDIP3 PE=1 SV=2 4.03 3036.7 - 452097 - - - 4.7447 - 2.758 0.532 - 241.7 1 1 0 0.0087 18 0 0 0 2.24E+07 1.05E+07 - - - 5.4618 0.9998 221125_WJC_METTL3_EV_vs_WT_F06.18971.18971.3 0.13 13/52 K.AVDIPHMDIEALK[136.11]K[136.11].L sp|P62906|RL10A_HUMAN 1 1594.8724 1.08 86920 18971 3 1594.874523 532.6314 60S ribosomal protein L10a OS=Homo sapiens OX=9606 GN=RPL10A PE=1 SV=2 5.38 3037.3 - 1.63E+06 - - - 1.3537 - 2.456 0.339 - 176.6 1 2 0 0.0022 14 0 0 0 4.47E+07 4.13E+07 - - - 4.7068 1 221125_WJC_METTL3_EV_vs_WT_F06.18972.18972.3 9.20E-15 17/96 K.LVQDVANNTNEEAGDGTTTATVLAR.S "sp|P10809|CH60_HUMAN,tr|C9JL25|C9JL25_HUMAN,tr|A0A7I2V2X6|A0A7I2V2X6_HUMAN,tr|A0A7I2YQK6|A0A7I2YQK6_HUMAN,tr|A0A7I2V599|A0A7I2V599_HUMAN,tr|E7EXB4|E7EXB4_HUMAN,tr|A0A7I2YQ71|A0A7I2YQ71_HUMAN,tr|E7ESH4|E7ESH4_HUMAN,tr|A0A7I2V5M1|A0A7I2V5M1_HUMAN,tr|A0A7I2V5K3|A0A7I2V5K3_HUMAN,tr|A0A7I2V369|A0A7I2V369_HUMAN" 11 2559.2413 1.05 86921 18972 3 2559.240953 854.0877 "60 kDa heat shock protein, mitochondrial OS=Homo sapiens OX=9606 GN=HSPD1 PE=1 SV=2" 3.92 3037.4 - 712061 - - - -0.1172 - 3.308 0.711 - 308 1 2 0 -0.0003 25 0 0 0 1.48E+07 1.40E+07 - - - 9.2192 0.9968 221125_WJC_METTL3_EV_vs_WT_F06.18974.18974.3 6.93E-06 17/84 K.VPEIEVTVEGPNNNNPQTSAVR[166.11].T "sp|P78347|GTF2I_HUMAN,tr|A0A494C1K3|A0A494C1K3_HUMAN" 2 2373.18 2.68 86923 18974 3 2374.17432 792.0673 General transcription factor II-I OS=Homo sapiens OX=9606 GN=GTF2I PE=1 SV=2 4.25 3037.7 - 532941 - - - 418.9876 - 3.309 0.559 - 261.7 1 2 0 0.9943 22 0 0 0 5.33E+06 1.99E+06 - - - 7.3339 1 221125_WJC_METTL3_EV_vs_WT_F06.18979.18979.3 8.50E-08 16/52 K.AVDIPHMDIEALKK.L sp|P62906|RL10A_HUMAN 1 1578.844 1.02 86926 18979 3 1578.846935 527.2886 60S ribosomal protein L10a OS=Homo sapiens OX=9606 GN=RPL10A PE=1 SV=2 5.38 3038.3 - 2.37E+06 - - - 1.8818 - 2.777 0.579 - 263.3 1 2 0 0.003 14 0 0 0 4.27E+07 4.20E+07 - - - 7.7088 1 221125_WJC_METTL3_EV_vs_WT_F06.18980.18980.4 5.87E-10 20/114 K.IFC[160.03]C[160.03]HGGLSPDLQSMEQIR[166.11]R[166.11].L "sp|P62136|PP1A_HUMAN,sp|P62140|PP1B_HUMAN,sp|P36873|PP1G_HUMAN,tr|E7ETD8|E7ETD8_HUMAN,tr|A0A7I2V4F7|A0A7I2V4F7_HUMAN,tr|F8W0W8|F8W0W8_HUMAN,tr|F8VYE8|F8VYE8_HUMAN,tr|F8VR82|F8VR82_HUMAN,tr|F8W1A0|F8W1A0_HUMAN" 9 2423.1411 0.92 86927 18980 4 2423.141557 606.7926 Serine\threonine-protein phosphatase PP1-alpha catalytic subunit OS=Homo sapiens OX=9606 GN=PPP1CA PE=1 SV=1 6.73 3038.4 - 1.29E+06 - - - 0.1762 - 3.525 0.602 - 246 1 2 0 0.0004 20 0 0 0 1.08E+07 1.17E+07 - - - 4.8869 1 221125_WJC_METTL3_EV_vs_WT_F06.18982.18982.4 2.47E-12 31/180 H.LLPSPEPSPEGSYVGQHSQGLGGHYADSYLK[136.11].R "tr|K7EQG2|K7EQG2_HUMAN,tr|E9PAU2|E9PAU2_HUMAN,tr|A0A087WZ13|A0A087WZ13_HUMAN" 3 3277.5771 1.54 86929 18982 4 3277.588458 820.4016 Uncharacterized protein (Fragment) OS=Homo sapiens OX=9606 PE=1 SV=1 5.27 3038.6 - 759774 - - - 3.4587 - 4.168 0.637 - 323.2 1 1 0 0.0113 31 0 0 0 1.26E+07 8.19E+06 - - - 5.2011 0.9998 221125_WJC_METTL3_EV_vs_WT_F06.18984.18984.4 0.00309 16/90 K.KIHTEPQLSAALEYVR.S "sp|P47897|SYQ_HUMAN,tr|A0A0U1RQL2|A0A0U1RQL2_HUMAN,tr|A0A0U1RRI9|A0A0U1RRI9_HUMAN,tr|A0A0U1RQT0|A0A0U1RQT0_HUMAN,tr|A0A1B0GVU9|A0A1B0GVU9_HUMAN,tr|A0A0U1RQE9|A0A0U1RQE9_HUMAN,tr|A0A0U1RQM8|A0A0U1RQM8_HUMAN,tr|A0A0U1RQU2|A0A0U1RQU2_HUMAN" 8 1853.9999 1.72 86931 18984 4 1854.000338 464.5073 Glutamine--tRNA ligase OS=Homo sapiens OX=9606 GN=QARS1 PE=1 SV=1 6.76 3038.9 - 698016 - - - 0.2109 - 2.738 0.368 - 247.4 1 2 0 0.0004 16 0 0 0 1.35E+07 7.84E+06 - - - 2.7838 0.9994 221125_WJC_METTL3_EV_vs_WT_F06.18985.18985.3 0.00087 Nov-76 R.DILELGGPEGDAASGTISK[136.11]K[136.11].D "sp|Q9NPF5|DMAP1_HUMAN,tr|Q5TG39|Q5TG39_HUMAN,tr|Q5TG38|Q5TG38_HUMAN,tr|Q5TG40|Q5TG40_HUMAN,tr|Q5TG36|Q5TG36_HUMAN" 5 1973.0288 0.97 86932 18985 3 1973.034306 658.6835 DNA methyltransferase 1-associated protein 1 OS=Homo sapiens OX=9606 GN=DMAP1 PE=1 SV=1 4.32 3039 - 366016 - - - 2.7901 - 2.499 0.343 - 78.7 1 2 0 0.0055 20 0 0 0 6.48E+06 6.70E+06 - - - 4.5846 0.9994 221125_WJC_METTL3_EV_vs_WT_F06.18986.18986.4 0.00461 Dec-96 R.MHTTFEHDIQALGTQVR.Q "sp|Q01082|SPTB2_HUMAN,tr|A0A087WUZ3|A0A087WUZ3_HUMAN" 2 1982.9632 1.8 86933 18986 4 1982.967773 496.7481 "Spectrin beta chain, non-erythrocytic 1 OS=Homo sapiens OX=9606 GN=SPTBN1 PE=1 SV=2" 5.95 3039.1 - 309160 - - - 2.284 - 1.685 0.367 - 68.8 1 2 0 0.0045 17 0 0 0 3.62E+06 2.02E+06 - - - 2.6003 1 221125_WJC_METTL3_EV_vs_WT_F06.18991.18991.3 9.34E-06 19/48 K.LK[136.11]DLFDYSPPLHK[136.11].N "sp|Q9NYF8|BCLF1_HUMAN,tr|E9PKI6|E9PKI6_HUMAN,tr|A0A1W2PQ43|A0A1W2PQ43_HUMAN,tr|E9PK91|E9PK91_HUMAN,tr|E9PK09|E9PK09_HUMAN,tr|E9PQN2|E9PQN2_HUMAN" 6 1587.8632 2.29 86936 18991 3 1587.863044 530.295 Bcl-2-associated transcription factor 1 OS=Homo sapiens OX=9606 GN=BCLAF1 PE=1 SV=2 6.75 3039.7 - 1.32E+06 - - - -0.0856 - 3.299 0.571 - 421.9 1 2 1 -0.0001 13 0 0 0 7.17E+07 3.14E+07 - - - 8.1423 1 221125_WJC_METTL3_EV_vs_WT_F06.18992.18992.3 2.25E-09 15/72 K.QLSSSVTGLTNIEEENC[160.03]QR.Y "sp|P46940|IQGA1_HUMAN,tr|A0A0J9YXZ5|A0A0J9YXZ5_HUMAN" 2 2164.0066 1.4 86937 18992 3 2164.005178 722.3428 Ras GTPase-activating-like protein IQGAP1 OS=Homo sapiens OX=9606 GN=IQGAP1 PE=1 SV=1 4.25 3039.8 - 1.07E+06 - - - -0.6691 - 3.287 0.551 - 225.8 1 2 0 -0.0014 19 0 0 0 1.02E+07 7.32E+06 - - - 7.6062 1 221125_WJC_METTL3_EV_vs_WT_F06.18994.18994.2 6.68E-09 15/36 K.QLSSSVTGLTNIEEENC[160.03]QR[166.11].Y "sp|P46940|IQGA1_HUMAN,tr|A0A0J9YXZ5|A0A0J9YXZ5_HUMAN" 2 2174.0149 0.64 86939 18994 2 2174.016021 1088.0147 Ras GTPase-activating-like protein IQGAP1 OS=Homo sapiens OX=9606 GN=IQGAP1 PE=1 SV=1 4.25 3040.1 - 363418 - - - 0.5175 - 3.451 0.653 - 583.3 1 2 0 0.0011 19 0 0 0 3.00E+06 4.67E+06 - - - 6.909 0.9999 221125_WJC_METTL3_EV_vs_WT_F06.18998.18998.3 1.42E-06 15/48 K.LKDLFDYSPPLHK.N "sp|Q9NYF8|BCLF1_HUMAN,tr|E9PKI6|E9PKI6_HUMAN,tr|A0A1W2PQ43|A0A1W2PQ43_HUMAN,tr|E9PK91|E9PK91_HUMAN,tr|E9PK09|E9PK09_HUMAN,tr|E9PQN2|E9PQN2_HUMAN" 6 1571.8348 1.95 86941 18998 3 1571.836867 524.9522 Bcl-2-associated transcription factor 1 OS=Homo sapiens OX=9606 GN=BCLAF1 PE=1 SV=2 6.75 3040.6 - 3.45E+06 - - - 1.3277 - 2.934 0.561 - 275.5 1 2 1 0.0021 13 0 0 0 5.65E+07 2.90E+07 - - - 7.7124 1 221125_WJC_METTL3_EV_vs_WT_F06.18999.18999.4 7.87E-06 20/78 R.QVTLSDLHC[160.03]LDLHR[166.11].M sp|Q8TBB5|KLDC4_HUMAN 1 1715.8653 0.55 86942 18999 4 1715.865729 429.9736 Kelch domain-containing protein 4 OS=Homo sapiens OX=9606 GN=KLHDC4 PE=1 SV=1 5.98 3040.7 - 1.07E+06 - - - 0.2739 - 3.287 0.474 - 399.4 1 2 0 0.0005 14 0 0 0 4.49E+06 8.22E+06 - - - 3.7846 0.9992 221125_WJC_METTL3_EV_vs_WT_F06.19000.19000.4 0.00129 12/108 R.YK[136.11]VPDGK[136.11]PENEFAFNAEFK[136.11].D sp|Q15181|IPYR_HUMAN 1 2253.1168 1.89 86943 19000 4 2253.119136 564.2865 Inorganic pyrophosphatase OS=Homo sapiens OX=9606 GN=PPA1 PE=1 SV=2 4.87 3040.8 - 2.10E+06 - - - 1.0213 - 2.479 0.375 - 119.9 1 2 1 0.0023 19 0 0 0 5.12E+07 2.71E+07 - - - 2.7965 1 221125_WJC_METTL3_EV_vs_WT_F06.19002.19002.3 7.05E-11 20/56 R.HNEFNPQHSLLVQFR.N sp|Q99717|SMAD5_HUMAN 1 1864.9333 1.29 86945 19002 3 1864.927768 622.6517 Mothers against decapentaplegic homolog 5 OS=Homo sapiens OX=9606 GN=SMAD5 PE=1 SV=1 6.92 3041 - 1.21E+06 - - - -2.9476 - 3.953 0.636 - 709.7 1 2 0 -0.0055 15 0 0 0 2.00E+07 1.56E+07 - - - 9.2158 1 221125_WJC_METTL3_EV_vs_WT_F06.19003.19003.3 1.11E-10 19/56 R.HNEFNPQHSLLVQFR[166.11].N sp|Q99717|SMAD5_HUMAN 1 1874.9415 1.34 86946 19003 3 1874.947531 625.9878 Mothers against decapentaplegic homolog 5 OS=Homo sapiens OX=9606 GN=SMAD5 PE=1 SV=1 6.92 3041.1 - 904570 - - - 3.198 - 3.954 0.641 - 669.2 1 2 0 0.006 15 0 0 0 2.46E+07 1.83E+07 - - - 9.272 1 221125_WJC_METTL3_EV_vs_WT_F06.19004.19004.4 9.77E-10 20/84 R.HNEFNPQHSLLVQFR[166.11].N sp|Q99717|SMAD5_HUMAN 1 1874.9415 0.99 86947 19004 4 1874.944244 469.7427 Mothers against decapentaplegic homolog 5 OS=Homo sapiens OX=9606 GN=SMAD5 PE=1 SV=1 6.92 3041.2 - 851836 - - - 1.4448 - 3.124 0.601 - 340.2 1 2 0 0.0027 15 0 0 0 9.25E+06 9.38E+06 - - - 4.8639 0.9999 221125_WJC_METTL3_EV_vs_WT_F06.19008.19008.4 4.09E-05 17/78 R.QVTLSDLHC[160.03]LDLHR.M sp|Q8TBB5|KLDC4_HUMAN 1 1705.857 0.56 86951 19008 4 1705.858367 427.4715 Kelch domain-containing protein 4 OS=Homo sapiens OX=9606 GN=KLHDC4 PE=1 SV=1 5.98 3041.7 - 518629 - - - 0.8078 - 3.043 0.461 - 370.4 1 2 0 0.0014 14 0 0 0 4.62E+06 8.22E+06 - - - 3.6432 1 221125_WJC_METTL3_EV_vs_WT_F06.19010.19010.2 3.00E-11 16/36 K.QLSSSVTGLTNIEEENC[160.03]QR.Y "sp|P46940|IQGA1_HUMAN,tr|A0A0J9YXZ5|A0A0J9YXZ5_HUMAN" 2 2164.0066 0.64 86953 19010 2 2164.011019 1083.0106 Ras GTPase-activating-like protein IQGAP1 OS=Homo sapiens OX=9606 GN=IQGAP1 PE=1 SV=1 4.25 3042 - 365515 - - - 2.03 - 3.359 0.686 - 715.9 1 2 0 0.0044 19 0 0 0 3.00E+06 4.67E+06 - - - 7.0853 0.9994 221125_WJC_METTL3_EV_vs_WT_F06.19015.19015.4 0.000127 Dec-72 K.LK[136.11]DLFDYSPPLHK[136.11].N "sp|Q9NYF8|BCLF1_HUMAN,tr|E9PKI6|E9PKI6_HUMAN,tr|A0A1W2PQ43|A0A1W2PQ43_HUMAN,tr|E9PK91|E9PK91_HUMAN,tr|E9PK09|E9PK09_HUMAN,tr|E9PQN2|E9PQN2_HUMAN" 6 1587.8632 2.26 86956 19015 4 1587.863886 397.9731 Bcl-2-associated transcription factor 1 OS=Homo sapiens OX=9606 GN=BCLAF1 PE=1 SV=2 6.75 3042.6 - 3.96E+06 - - - 0.4446 - 2.043 0.396 - 120.8 1 2 1 0.0007 13 0 0 0 1.18E+08 5.23E+07 - - - 2.9375 0.9999 221125_WJC_METTL3_EV_vs_WT_F06.19016.19016.4 3.41E-08 25/150 R.TLVNKEEPPKELPAAEPVLSPLEGTK.M "sp|Q9BY77|PDIP3_HUMAN,tr|F6VRR5|F6VRR5_HUMAN" 2 2785.5113 1.75 86957 19016 4 2785.513305 697.3851 Polymerase delta-interacting protein 3 OS=Homo sapiens OX=9606 GN=POLDIP3 PE=1 SV=2 4.65 3042.7 - 4.07E+06 - - - 0.7101 - 4.126 0.576 - 397.9 1 2 2 0.002 26 0 0 0 1.39E+09 7.95E+08 - - - 4.686 0.9999 221125_WJC_METTL3_EV_vs_WT_F06.19017.19017.4 1.44E-07 23/150 R.TLVNK[136.11]EEPPK[136.11]ELPAAEPVLSPLEGTK[136.11].M "sp|Q9BY77|PDIP3_HUMAN,tr|F6VRR5|F6VRR5_HUMAN" 2 2809.5539 1.75 86958 19017 4 2809.555993 703.3958 Polymerase delta-interacting protein 3 OS=Homo sapiens OX=9606 GN=POLDIP3 PE=1 SV=2 4.65 3042.8 - 2.63E+06 - - - 0.7353 - 3.881 0.591 - 329.3 1 2 2 0.0021 26 0 0 0 1.39E+09 7.95E+08 - - - 4.7972 0.984 221125_WJC_METTL3_EV_vs_WT_F06.19019.19019.4 0.0252 10/108 R.YKVPDGKPENEFAFNAEFK.D sp|Q15181|IPYR_HUMAN 1 2229.0742 1.89 86960 19019 4 2229.078964 558.2758 Inorganic pyrophosphatase OS=Homo sapiens OX=9606 GN=PPA1 PE=1 SV=2 4.87 3042.9 - 1.62E+06 - - - 2.1215 - 2.171 0.254 - 89.6 1 2 1 0.0047 19 0 0 0 5.12E+07 2.72E+07 - - - 1.6977 0.9997 221125_WJC_METTL3_EV_vs_WT_F06.19020.19020.4 1.37E-10 15/84 R.HNEFNPQHSLLVQFR.N sp|Q99717|SMAD5_HUMAN 1 1864.9333 0.99 86961 19020 4 1864.928078 467.2406 Mothers against decapentaplegic homolog 5 OS=Homo sapiens OX=9606 GN=SMAD5 PE=1 SV=1 6.92 3043 - 1.37E+06 - - - -2.7813 - 3.542 0.393 - 241.3 1 2 0 -0.0052 15 0 0 0 9.25E+06 9.33E+06 - - - 3.0978 1 221125_WJC_METTL3_EV_vs_WT_F06.19021.19021.3 6.65E-11 28/56 K.HLEINPDHSIIETLR[166.11].Q sp|P07900|HS90A_HUMAN 1 1795.9456 0.54 86962 19021 3 1795.949618 599.6558 Heat shock protein HSP 90-alpha OS=Homo sapiens OX=9606 GN=HSP90AA1 PE=1 SV=5 5.27 3043.1 - 1.23E+06 - - - 2.2278 - 4.491 0.655 - 1588.1 1 2 0 0.004 15 0 0 0 2.33E+07 4.32E+07 - - - 9.761 1 221125_WJC_METTL3_EV_vs_WT_F06.19022.19022.3 8.96E-12 23/80 K.GNLYSFGC[160.03]PEYGQLGHNSDGK[136.11].F sp|Q9P258|RCC2_HUMAN 1 2307.0106 0.62 86963 19022 3 2307.013944 770.0108 Protein RCC2 OS=Homo sapiens OX=9606 GN=RCC2 PE=1 SV=2 5.32 3043.2 - 741188 - - - 1.4517 - 3.861 0.678 - 538.8 1 2 0 0.0033 21 0 0 0 3.90E+06 6.34E+06 - - - 9.3369 0.9983 221125_WJC_METTL3_EV_vs_WT_F06.19024.19024.4 0.000715 13/108 R.VNDQEGREEFYVHYVGFNR.R sp|Q9H7Z6|KAT8_HUMAN 1 2357.0825 0.67 86965 19024 4 2357.086525 590.2779 Histone acetyltransferase KAT8 OS=Homo sapiens OX=9606 GN=KAT8 PE=1 SV=2 4.83 3043.5 - 528289 - - - 1.7042 - 2.158 0.355 - 49.6 1 2 1 0.004 19 0 0 0 4.91E+06 7.36E+06 - - - 2.575 0.9876 221125_WJC_METTL3_EV_vs_WT_F06.19025.19025.4 0.0133 Oct-84 R.LDPNKYPVPENWLHK.E "sp|P39748|FEN1_HUMAN,tr|I3L3E9|I3L3E9_HUMAN" 2 1848.9523 1.39 86966 19025 4 1848.949026 463.2453 Flap endonuclease 1 OS=Homo sapiens OX=9606 GN=FEN1 PE=1 SV=1 6.75 3043.6 - 355559 - - - -1.754 - 2.095 0.251 - 78.5 1 2 1 -0.0032 15 0 0 0 7.68E+06 5.51E+06 - - - 1.6744 0.9999 221125_WJC_METTL3_EV_vs_WT_F06.19027.19027.4 1.54E-07 16/84 K.DR[166.11]PINFTQQHMPYFR[166.11].K sp|Q9P0U3|SENP1_HUMAN 1 1968.9532 0.93 86968 19027 4 1968.958768 493.2456 Sentrin-specific protease 1 OS=Homo sapiens OX=9606 GN=SENP1 PE=1 SV=2 8.75 3043.9 - 245404 - - - 2.8401 - 2.773 0.483 - 250.4 1 2 0 0.0056 15 0 0 0 3.10E+06 3.32E+06 - - - 3.7934 1 221125_WJC_METTL3_EV_vs_WT_F06.19031.19031.3 7.52E-10 18/52 K.HGYIGEFEIIDDHR.A "sp|P62244|RS15A_HUMAN,tr|I3L246|I3L246_HUMAN,tr|I3L3P7|I3L3P7_HUMAN,tr|H3BN98|H3BN98_HUMAN" 4 1699.7954 1.72 86970 19031 3 1699.797096 567.6058 40S ribosomal protein S15a OS=Homo sapiens OX=9606 GN=RPS15A PE=1 SV=2 4.72 3044.3 - 1.85E+06 - - - 0.9778 - 3.373 0.636 - 475.4 1 2 0 0.0017 14 0 0 0 3.16E+08 1.83E+08 - - - 8.8613 1 221125_WJC_METTL3_EV_vs_WT_F06.19033.19033.3 2.68E-09 18/52 K.HGYIGEFEIIDDHR[166.11].A "sp|P62244|RS15A_HUMAN,tr|I3L246|I3L246_HUMAN,tr|I3L3P7|I3L3P7_HUMAN,tr|H3BN98|H3BN98_HUMAN" 4 1709.8037 1.72 86972 19033 3 1709.806099 570.9418 40S ribosomal protein S15a OS=Homo sapiens OX=9606 GN=RPS15A PE=1 SV=2 4.72 3044.5 - 3.00E+06 - - - 1.4007 - 3.37 0.625 - 458.1 1 2 0 0.0024 14 0 0 0 3.15E+08 1.83E+08 - - - 8.7361 0.9997 221125_WJC_METTL3_EV_vs_WT_F06.19034.19034.4 2.81E-06 18/90 R.LDAPVDYFYR[166.11]PETQHR[166.11].E "sp|Q9Y5Q8|TF3C5_HUMAN,tr|Q5T7U1|Q5T7U1_HUMAN,tr|Q5T7U4|Q5T7U4_HUMAN,tr|Q5T7U0|Q5T7U0_HUMAN" 4 2025.9812 0.52 86973 19034 4 2025.985714 507.5026 General transcription factor 3C polypeptide 5 OS=Homo sapiens OX=9606 GN=GTF3C5 PE=1 SV=2 5.38 3044.5 - 2.22E+06 - - - 2.2453 - 2.957 0.389 - 292.2 1 2 0 0.0045 16 0 0 0 1.49E+07 2.86E+07 - - - 2.9925 0.781 221125_WJC_METTL3_EV_vs_WT_F06.19035.19035.3 0.00677 17/84 K.VTFFEPGSGDENGTSNKEDEFR.M "sp|O95793|STAU1_HUMAN,tr|Q5JW30|Q5JW30_HUMAN" 2 2461.067 -1 86974 19035 3 2462.054964 821.3629 Double-stranded RNA-binding protein Staufen homolog 1 OS=Homo sapiens OX=9606 GN=STAU1 PE=1 SV=2 4.08 3044.6 - 1.65E+06 - - - 401.4466 - 2.288 0.5 - 188.6 1 2 1 0.988 22 0 0 0 0.00E+00 0.00E+00 - - - 5.8031 1 221125_WJC_METTL3_EV_vs_WT_F06.19036.19036.3 3.15E-08 18/64 K.SDK[136.11]TEEIAEEEETVFPK[136.11].A sp|Q9NR30|DDX21_HUMAN 1 1995.9495 1.21 86975 19036 3 1995.951498 666.3238 Nucleolar RNA helicase 2 OS=Homo sapiens OX=9606 GN=DDX21 PE=1 SV=5 4.06 3044.7 - 1.06E+06 - - - 0.977 - 3.646 0.602 - 428.1 1 2 1 0.0019 17 0 0 0 1.22E+07 1.00E+07 - - - 8.5193 1 221125_WJC_METTL3_EV_vs_WT_F06.19038.19038.3 4.16E-18 34/100 R.TLVNKEEPPKELPAAEPVLSPLEGTK.M "sp|Q9BY77|PDIP3_HUMAN,tr|F6VRR5|F6VRR5_HUMAN" 2 2785.5113 1.78 86977 19038 3 2785.512975 929.5111 Polymerase delta-interacting protein 3 OS=Homo sapiens OX=9606 GN=POLDIP3 PE=1 SV=2 4.65 3045 - 919557 - - - 0.5916 - 5.083 0.745 - 1056.6 1 2 2 0.0016 26 0 0 0 1.99E+08 1.12E+08 - - - 10.5862 1 221125_WJC_METTL3_EV_vs_WT_F06.19039.19039.3 1.63E-05 16/44 K.WIGLDLSNGK[136.11]PR[166.11].D "sp|P17987|TCPA_HUMAN,tr|F5H282|F5H282_HUMAN,tr|E7EQR6|E7EQR6_HUMAN" 3 1372.7582 0.35 86978 19039 3 1372.75994 458.5933 T-complex protein 1 subunit alpha OS=Homo sapiens OX=9606 GN=TCP1 PE=1 SV=1 8.75 3045.1 - 827276 - - - 1.2646 - 2.82 0.476 - 528.7 1 2 0 0.0017 12 0 0 0 2.07E+06 5.88E+06 - - - 6.7201 1 221125_WJC_METTL3_EV_vs_WT_F06.19040.19040.4 2.12E-07 18/108 K.EHGVPILISEIHPGQPADR.C "sp|Q9HD26|GOPC_HUMAN,tr|A0A0J9YVX5|A0A0J9YVX5_HUMAN" 2 2064.0752 1.55 86979 19040 4 2064.078599 517.0261 Golgi-associated PDZ and coiled-coil motif-containing protein OS=Homo sapiens OX=9606 GN=GOPC PE=1 SV=1 5.28 3045.2 - 796799 - - - 1.6283 - 3.444 0.48 - 177.6 1 2 0 0.0034 19 0 0 0 8.42E+06 5.45E+06 - - - 3.8213 0.9932 221125_WJC_METTL3_EV_vs_WT_F06.19041.19041.4 5.30E-06 17/108 R.VAIHYINPPNPAKDNFTFK.C "sp|P78406|RAE1L_HUMAN,tr|E9PQ57|E9PQ57_HUMAN" 2 2185.132 1.64 86980 19041 4 2185.145881 547.2903 mRNA export factor OS=Homo sapiens OX=9606 GN=RAE1 PE=1 SV=1 8.48 3045.3 - 735165 - - - 6.3415 - 3.14 0.46 - 291.5 1 2 1 0.0139 19 0 0 0 5.81E+06 3.54E+06 - - - 3.6131 0.9985 221125_WJC_METTL3_EV_vs_WT_F06.19044.19044.4 0.000171 16/102 K.GSYTAQFEHTILLR[166.11]PTC[160.03]K[136.11].E "sp|P50579|MAP2_HUMAN,tr|F8VQZ7|F8VQZ7_HUMAN,tr|F8VRR3|F8VRR3_HUMAN" 3 2139.0902 1.32 86983 19044 4 2139.095979 535.7798 Methionine aminopeptidase 2 OS=Homo sapiens OX=9606 GN=METAP2 PE=1 SV=1 8.21 3045.7 - 416530 - - - 2.711 - 2.213 0.319 - 131.7 1 2 0 0.0058 18 0 0 0 5.81E+06 4.39E+06 - - - 2.2731 1 221125_WJC_METTL3_EV_vs_WT_F06.19047.19047.2 2.18E-09 16/38 R.VNSASSSNPPAEVDPDTILK.A "sp|Q9BY77|PDIP3_HUMAN,tr|F6VRR5|F6VRR5_HUMAN" 2 2040.0011 1.82 86986 19047 2 2040.004727 1021.0078 Polymerase delta-interacting protein 3 OS=Homo sapiens OX=9606 GN=POLDIP3 PE=1 SV=2 4.03 3046.1 - 325903 - - - 1.7637 - 3.535 0.657 - 428.9 1 2 0 0.0036 20 0 0 0 2.16E+08 1.19E+08 - - - 6.9969 0.9999 221125_WJC_METTL3_EV_vs_WT_F06.19048.19048.3 0.00287 Dec-44 K.WIGLDLSNGKPR.D "sp|P17987|TCPA_HUMAN,tr|F5H282|F5H282_HUMAN,tr|E7EQR6|E7EQR6_HUMAN" 3 1354.7357 0.35 86987 19048 3 1354.737804 452.5859 T-complex protein 1 subunit alpha OS=Homo sapiens OX=9606 GN=TCP1 PE=1 SV=1 8.75 3046.2 - 273252 - - - 1.528 - 2.673 0.407 - 270.3 1 2 0 0.0021 12 0 0 0 2.07E+06 5.88E+06 - - - 5.8024 0.997 221125_WJC_METTL3_EV_vs_WT_F06.19051.19051.3 6.37E-08 20/96 K.LVQDVANNTNEEAGDGTTTATVLAR[166.11].S "sp|P10809|CH60_HUMAN,tr|C9JL25|C9JL25_HUMAN,tr|A0A7I2V2X6|A0A7I2V2X6_HUMAN,tr|A0A7I2YQK6|A0A7I2YQK6_HUMAN,tr|A0A7I2V599|A0A7I2V599_HUMAN,tr|E7EXB4|E7EXB4_HUMAN,tr|A0A7I2YQ71|A0A7I2YQ71_HUMAN,tr|E7ESH4|E7ESH4_HUMAN,tr|A0A7I2V5M1|A0A7I2V5M1_HUMAN,tr|A0A7I2V5K3|A0A7I2V5K3_HUMAN,tr|A0A7I2V369|A0A7I2V369_HUMAN" 11 2569.2495 0.91 86989 19051 3 2569.253669 857.4238 "60 kDa heat shock protein, mitochondrial OS=Homo sapiens OX=9606 GN=HSPD1 PE=1 SV=2" 3.92 3046.6 - 848235 - - - 1.6137 - 3.441 0.131 - 420.1 1 2 0 0.0041 25 0 0 0 7.87E+06 8.67E+06 - - - 2.8424 0.9999 221125_WJC_METTL3_EV_vs_WT_F06.19053.19053.3 6.23E-08 20/76 R.VNSASSSNPPAEVDPDTILK.A "sp|Q9BY77|PDIP3_HUMAN,tr|F6VRR5|F6VRR5_HUMAN" 2 2040.0011 1.71 86991 19053 3 2040.007925 681.0077 Polymerase delta-interacting protein 3 OS=Homo sapiens OX=9606 GN=POLDIP3 PE=1 SV=2 4.03 3046.8 - 1.18E+06 - - - 3.3314 - 3.527 0.564 - 427.4 1 2 0 0.0068 20 0 0 0 3.28E+08 1.92E+08 - - - 7.884 1 221125_WJC_METTL3_EV_vs_WT_F06.19054.19054.3 1.55E-13 30/100 R.TLVNK[136.11]EEPPK[136.11]ELPAAEPVLSPLEGTK[136.11].M "sp|Q9BY77|PDIP3_HUMAN,tr|F6VRR5|F6VRR5_HUMAN" 2 2809.5539 1.78 86992 19054 3 2809.55546 937.5253 Polymerase delta-interacting protein 3 OS=Homo sapiens OX=9606 GN=POLDIP3 PE=1 SV=2 4.65 3046.9 - 1.16E+06 - - - 0.5456 - 4.962 0.681 - 660 1 2 2 0.0015 26 0 0 0 1.99E+08 1.12E+08 - - - 9.8172 1 221125_WJC_METTL3_EV_vs_WT_F06.19055.19055.3 4.28E-09 17/76 R.VNSASSSNPPAEVDPDTILK[136.11].A "sp|Q9BY77|PDIP3_HUMAN,tr|F6VRR5|F6VRR5_HUMAN" 2 2048.0153 1.71 86993 19055 3 2048.01729 683.6791 Polymerase delta-interacting protein 3 OS=Homo sapiens OX=9606 GN=POLDIP3 PE=1 SV=2 4.03 3047 - 1.10E+06 - - - 0.9575 - 3.355 0.619 - 322.5 1 2 0 0.002 20 0 0 0 3.27E+08 1.92E+08 - - - 8.3773 1 221125_WJC_METTL3_EV_vs_WT_F06.19057.19057.4 3.36E-07 18/78 K.HGYIGEFEIIDDHR[166.11].A "sp|P62244|RS15A_HUMAN,tr|I3L246|I3L246_HUMAN,tr|I3L3P7|I3L3P7_HUMAN,tr|H3BN98|H3BN98_HUMAN" 4 1709.8037 0.93 86995 19057 4 1709.805566 428.4582 40S ribosomal protein S15a OS=Homo sapiens OX=9606 GN=RPS15A PE=1 SV=2 4.72 3047.2 - 887993 - - - 1.089 - 2.892 0.588 - 302.8 1 2 0 0.0019 14 0 0 0 1.67E+07 1.80E+07 - - - 4.7299 1 221125_WJC_METTL3_EV_vs_WT_F06.19059.19059.4 5.68E-07 18/78 K.HGYIGEFEIIDDHR.A "sp|P62244|RS15A_HUMAN,tr|I3L246|I3L246_HUMAN,tr|I3L3P7|I3L3P7_HUMAN,tr|H3BN98|H3BN98_HUMAN" 4 1699.7954 0.93 86997 19059 4 1699.798703 425.9561 40S ribosomal protein S15a OS=Homo sapiens OX=9606 GN=RPS15A PE=1 SV=2 4.72 3047.5 - 714925 - - - 1.9232 - 2.644 0.575 - 288.8 1 2 0 0.0033 14 0 0 0 1.67E+07 1.80E+07 - - - 4.5838 1 221125_WJC_METTL3_EV_vs_WT_F06.19061.19061.4 5.72E-10 16/84 K.HLEINPDHSIIETLR[166.11].Q sp|P07900|HS90A_HUMAN 1 1795.9456 0.69 86999 19061 4 1795.949739 449.9937 Heat shock protein HSP 90-alpha OS=Homo sapiens OX=9606 GN=HSP90AA1 PE=1 SV=5 5.27 3047.8 - 636509 - - - 2.2952 - 3.016 0.535 - 304.5 1 2 0 0.0041 15 0 0 0 6.65E+06 9.60E+06 - - - 4.2765 0.9957 221125_WJC_METTL3_EV_vs_WT_F06.19062.19062.4 0.000118 17/180 H.LLPSPEPSPEGSYVGQHSQGLGGHYADSYLK.R "tr|K7EQG2|K7EQG2_HUMAN,tr|E9PAU2|E9PAU2_HUMAN,tr|A0A087WZ13|A0A087WZ13_HUMAN" 3 3269.5629 1.54 87000 19062 4 3269.568155 818.398 Uncharacterized protein (Fragment) OS=Homo sapiens OX=9606 PE=1 SV=1 5.27 3047.9 - 562129 - - - 1.6005 - 2.922 0.519 - 102.9 1 1 0 0.0052 31 0 0 0 1.26E+07 8.19E+06 - - - 4.0678 1 221125_WJC_METTL3_EV_vs_WT_F06.19063.19063.4 3.26E-10 15/84 K.HLEINPDHSIIETLR.Q sp|P07900|HS90A_HUMAN 1 1785.9373 0.69 87001 19063 4 1785.938842 447.4916 Heat shock protein HSP 90-alpha OS=Homo sapiens OX=9606 GN=HSP90AA1 PE=1 SV=5 5.27 3048 - 514584 - - - 0.8371 - 2.963 0.521 - 252.8 1 2 0 0.0015 15 0 0 0 6.60E+06 9.60E+06 - - - 4.149 0.9998 221125_WJC_METTL3_EV_vs_WT_F06.19064.19064.4 0.00327 17/120 K.LISVETDIVVDHYKEEKFEDR.S "sp|Q12931|TRAP1_HUMAN,tr|I3L0K7|I3L0K7_HUMAN" 2 2563.2806 2.18 87002 19064 4 2563.286352 641.8274 "Heat shock protein 75 kDa, mitochondrial OS=Homo sapiens OX=9606 GN=TRAP1 PE=1 SV=3" 4.43 3048.2 - 432698 - - - 2.2444 - 3.436 0.507 - 153.1 1 2 2 0.0058 21 0 0 0 1.89E+06 8.67E+05 - - - 4.0454 0.9976 221125_WJC_METTL3_EV_vs_WT_F06.19066.19066.3 1.44E-08 17/100 R.GSVLNSYSAQPNFGAPASPAGSNPAR.P "tr|B4DHE8|B4DHE8_HUMAN,tr|A0A6Q8PF05|A0A6Q8PF05_HUMAN" 2 2516.2044 2.31 87004 19066 3 2516.209048 839.7421 RNA-binding protein Musashi homolog 2 OS=Homo sapiens OX=9606 GN=MSI2 PE=1 SV=1 8.75 3048.4 - 376987 - - - 1.8417 - 3.125 0.595 - 168.9 1 1 0 0.0046 26 0 0 0 2.88E+06 1.24E+06 - - - 7.7938 0.9994 221125_WJC_METTL3_EV_vs_WT_F06.19069.19069.4 7.66E-06 13/72 K.NKDWVFINYTYKR.F sp|Q15208|STK38_HUMAN 1 1745.8889 1.63 87007 19069 4 1745.891711 437.4795 Serine\threonine-protein kinase 38 OS=Homo sapiens OX=9606 GN=STK38 PE=1 SV=1 9.53 3048.8 - 245820 - - - 1.5872 - 2.825 0.403 - 200.1 1 2 1 0.0028 13 0 0 0 3.03E+06 1.86E+06 - - - 3.118 0.9999 221125_WJC_METTL3_EV_vs_WT_F06.19074.19074.3 1.59E-09 15/60 K.AK[136.11]DDSELEGQVISC[160.03]LK[136.11].L sp|Q92896|GSLG1_HUMAN 1 1806.9004 1.02 87010 19074 3 1806.901601 603.3074 Golgi apparatus protein 1 OS=Homo sapiens OX=9606 GN=GLG1 PE=1 SV=2 4.32 3049.3 - 1.85E+06 - - - 0.6481 - 2.88 0.551 - 318.7 1 2 1 0.0012 16 0 0 0 2.08E+07 2.03E+07 - - - 7.3969 1 221125_WJC_METTL3_EV_vs_WT_F06.19076.19076.2 3.48E-10 16/38 R.VNSASSSNPPAEVDPDTILK[136.11].A "sp|Q9BY77|PDIP3_HUMAN,tr|F6VRR5|F6VRR5_HUMAN" 2 2048.0153 1.82 87012 19076 2 2048.016252 1025.0149 Polymerase delta-interacting protein 3 OS=Homo sapiens OX=9606 GN=POLDIP3 PE=1 SV=2 4.03 3049.5 - 1.03E+06 - - - 0.4507 - 3.287 0.606 - 413 1 2 0 0.0009 20 0 0 0 2.16E+08 1.19E+08 - - - 6.4422 0.9994 221125_WJC_METTL3_EV_vs_WT_F06.19077.19077.3 0.000696 14/60 K.YFLHDDRDDGVDYWAK.R "sp|Q9NYF8|BCLF1_HUMAN,tr|H0YF14|H0YF14_HUMAN" 2 2013.8857 2.29 87013 19077 3 2013.885028 672.3025 Bcl-2-associated transcription factor 1 OS=Homo sapiens OX=9606 GN=BCLAF1 PE=1 SV=2 4.28 3049.6 - 785365 - - - -0.3367 - 2.672 0.349 - 209.6 1 2 1 -0.0007 16 0 0 0 2.44E+08 1.06E+08 - - - 4.9526 0.9999 221125_WJC_METTL3_EV_vs_WT_F06.19078.19078.3 0.0033 16/60 R.LDAPVDYFYR[166.11]PETQHR[166.11].E "sp|Q9Y5Q8|TF3C5_HUMAN,tr|Q5T7U1|Q5T7U1_HUMAN,tr|Q5T7U4|Q5T7U4_HUMAN,tr|Q5T7U0|Q5T7U0_HUMAN" 4 2025.9812 0.05 87014 19078 3 2025.978175 676.3343 General transcription factor 3C polypeptide 5 OS=Homo sapiens OX=9606 GN=GTF3C5 PE=1 SV=2 5.38 3049.8 - 608246 - - - -1.4758 - 2.971 0.42 - 431.6 1 2 0 -0.003 16 0 0 0 3.14E+05 6.06E+06 - - - 6.0157 0.9999 221125_WJC_METTL3_EV_vs_WT_F06.19081.19081.4 7.69E-06 13/96 K.KIEVIKPGDLGVDLTSK.L "sp|P38117|ETFB_HUMAN,tr|M0QY67|M0QY67_HUMAN" 2 1811.0404 1.85 87017 19081 4 1811.04063 453.7674 Electron transfer flavoprotein subunit beta OS=Homo sapiens OX=9606 GN=ETFB PE=1 SV=3 6.12 3050.2 - 411626 - - - 0.1187 - 2.507 0.434 - 125.2 1 2 0 0.0002 17 0 0 0 5.37E+07 2.91E+07 - - - 3.3226 1 221125_WJC_METTL3_EV_vs_WT_F06.19086.19086.2 1.70E-10 15/28 K.QC[160.03]ANLQNAIADAEQR.G "sp|P13647|K2C5_HUMAN,tr|H0YI76|H0YI76_HUMAN" 2 1700.79 436.78 87020 19086 2 1700.790333 851.4023 "Keratin, type II cytoskeletal 5 OS=Homo sapiens OX=9606 GN=KRT5 PE=1 SV=3" 4.37 3050.8 - 4.41E+06 - - - 0.1776 - 3.336 0.7 - 957.5 1 2 0 0.0003 15 0 0 0 2.28E+08 5.23E+05 - - - 7.1731 0.9998 221125_WJC_METTL3_EV_vs_WT_F06.19087.19087.4 2.14E-05 Dec-90 K.YFLHDDR[166.11]DDGVDYWAK[136.11].R "sp|Q9NYF8|BCLF1_HUMAN,tr|H0YF14|H0YF14_HUMAN" 2 2031.9082 2.22 87021 19087 4 2031.909183 508.9843 Bcl-2-associated transcription factor 1 OS=Homo sapiens OX=9606 GN=BCLAF1 PE=1 SV=2 4.28 3050.9 - 1.73E+06 - - - 0.4956 - 2.286 0.483 - 96 1 2 1 0.001 16 0 0 0 4.07E+08 1.83E+08 - - - 3.721 0.9999 221125_WJC_METTL3_EV_vs_WT_F06.19091.19091.3 5.52E-07 22/64 K.TQLIAHDK[136.11]EVYDIAFSR[166.11].A "sp|P61962|DCAF7_HUMAN,tr|A0A087WWI6|A0A087WWI6_HUMAN" 2 2023.0494 1.35 87025 19091 3 2023.054049 675.3571 DDB1- and CUL4-associated factor 7 OS=Homo sapiens OX=9606 GN=DCAF7 PE=1 SV=1 5.35 3051.4 - 783326 - - - 2.3173 - 3.716 0.567 - 760.8 1 2 1 0.0047 17 0 0 0 7.93E+07 5.86E+07 - - - 8.1763 0.9999 221125_WJC_METTL3_EV_vs_WT_F06.19092.19092.3 1.69E-06 16/60 K.YFLHDDR[166.11]DDGVDYWAK[136.11].R "sp|Q9NYF8|BCLF1_HUMAN,tr|H0YF14|H0YF14_HUMAN" 2 2031.9082 2.29 87026 19092 3 2031.910551 678.31 Bcl-2-associated transcription factor 1 OS=Homo sapiens OX=9606 GN=BCLAF1 PE=1 SV=2 4.28 3051.4 - 755533 - - - 1.1689 - 2.632 0.552 - 265.2 1 2 1 0.0024 16 0 0 0 2.44E+08 1.06E+08 - - - 7.1767 1 221125_WJC_METTL3_EV_vs_WT_F06.19094.19094.3 0.000472 17/64 K.K[136.11]IEVIK[136.11]PGDLGVDLTSK[136.11].L "sp|P38117|ETFB_HUMAN,tr|M0QY67|M0QY67_HUMAN" 2 1835.083 1.91 87028 19094 3 1835.082453 612.7016 Electron transfer flavoprotein subunit beta OS=Homo sapiens OX=9606 GN=ETFB PE=1 SV=3 6.12 3051.7 - 534494 - - - -0.3063 - 2.491 0.476 - 206.4 1 2 0 -0.0006 17 0 0 0 7.05E+07 3.69E+07 - - - 6.1525 0.9987 221125_WJC_METTL3_EV_vs_WT_F06.19097.19097.4 0.000123 Dec-72 K.LKDLFDYSPPLHK.N "sp|Q9NYF8|BCLF1_HUMAN,tr|E9PKI6|E9PKI6_HUMAN,tr|A0A1W2PQ43|A0A1W2PQ43_HUMAN,tr|E9PK91|E9PK91_HUMAN,tr|E9PK09|E9PK09_HUMAN,tr|E9PQN2|E9PQN2_HUMAN" 6 1571.8348 2.6 87030 19097 4 1571.83603 393.966 Bcl-2-associated transcription factor 1 OS=Homo sapiens OX=9606 GN=BCLAF1 PE=1 SV=2 6.75 3052.1 - 1.42E+07 - - - 0.7952 - 1.76 0.361 - 121 1 2 1 0.0013 13 0 0 0 1.98E+08 7.61E+07 - - - 2.5774 0.9998 221125_WJC_METTL3_EV_vs_WT_F06.19099.19099.3 2.00E-10 17/64 K.TQLIAHDKEVYDIAFSR.A "sp|P61962|DCAF7_HUMAN,tr|A0A087WWI6|A0A087WWI6_HUMAN" 2 2005.0269 1.35 87031 19099 3 2005.032816 669.3496 DDB1- and CUL4-associated factor 7 OS=Homo sapiens OX=9606 GN=DCAF7 PE=1 SV=1 5.35 3052.3 - 2.09E+06 - - - 2.9551 - 3.411 0.605 - 332.2 1 2 1 0.0059 17 0 0 0 7.93E+07 5.86E+07 - - - 8.3833 0.9996 221125_WJC_METTL3_EV_vs_WT_F06.19100.19100.4 1.89E-05 15/96 K.TQLIAHDKEVYDIAFSR.A "sp|P61962|DCAF7_HUMAN,tr|A0A087WWI6|A0A087WWI6_HUMAN" 2 2005.0269 1.4 87032 19100 4 2005.025567 502.264 DDB1- and CUL4-associated factor 7 OS=Homo sapiens OX=9606 GN=DCAF7 PE=1 SV=1 5.35 3052.3 - 2.14E+06 - - - -0.6603 - 2.587 0.425 - 155.5 1 2 1 -0.0013 17 0 0 0 8.32E+07 5.95E+07 - - - 3.2548 0.9997 221125_WJC_METTL3_EV_vs_WT_F06.19102.19102.3 2.48E-05 Dec-64 R.DVQGTDASLDEELDRVK.M "sp|Q9UJZ1|STML2_HUMAN,tr|A0A087WYB4|A0A087WYB4_HUMAN" 2 1888.9014 2.18 87034 19102 3 1888.904776 630.6411 "Stomatin-like protein 2, mitochondrial OS=Homo sapiens OX=9606 GN=STOML2 PE=1 SV=1" 3.96 3052.4 - 1.49E+06 - - - 1.7793 - 2.515 0.48 - 110.2 1 2 1 0.0034 17 0 0 0 2.95E+07 1.35E+07 - - - 6.2205 0.9975 221125_WJC_METTL3_EV_vs_WT_F06.19103.19103.3 1.43E-06 15/60 F.MAEHLEETLSAVTNNR.Q "sp|Q9NRA8|4ET_HUMAN,tr|B1AKL4|B1AKL4_HUMAN,tr|B0QYZ7|B0QYZ7_HUMAN" 3 1813.8629 0.92 87035 19103 3 1813.864171 605.6282 Eukaryotic translation initiation factor 4E transporter OS=Homo sapiens OX=9606 GN=EIF4ENIF1 PE=1 SV=2 4.75 3052.5 - 1.49E+06 - - - 0.7217 - 2.553 0.527 - 263.8 1 1 0 0.0013 16 0 0 0 2.41E+07 2.62E+07 - - - 6.8201 1 221125_WJC_METTL3_EV_vs_WT_F06.19104.19104.3 6.40E-14 22/56 K.HLEINPDHSIIETLR.Q sp|P07900|HS90A_HUMAN 1 1785.9373 0.54 87036 19104 3 1785.940244 596.3197 Heat shock protein HSP 90-alpha OS=Homo sapiens OX=9606 GN=HSP90AA1 PE=1 SV=5 5.27 3052.6 - 1.26E+06 - - - 1.6221 - 4.312 0.646 - 918.6 1 2 0 0.0029 15 0 0 0 2.33E+07 4.32E+07 - - - 9.5548 1 221125_WJC_METTL3_EV_vs_WT_F06.19106.19106.3 1.05E-10 22/92 K.DGAVNGPSVVGDQTPIEPQTSIER[166.11].L sp|P49321|NASP_HUMAN 1 2475.2117 1.38 87038 19106 3 2475.214775 826.0778 Nuclear autoantigenic sperm protein OS=Homo sapiens OX=9606 GN=NASP PE=1 SV=2 3.92 3052.9 - 788597 - - - 1.25 - 3.647 0.638 - 349.2 1 2 0 0.0031 24 0 0 0 2.23E+07 1.62E+07 - - - 8.6574 0.9999 221125_WJC_METTL3_EV_vs_WT_F06.19108.19108.3 3.39E-06 18/60 K.FEK[136.11]DFDFESANAQFNK[136.11].E "sp|Q8ND56|LS14A_HUMAN,tr|A0A140TA76|A0A140TA76_HUMAN,tr|K7EMZ9|K7EMZ9_HUMAN" 3 1951.8923 1.04 87040 19108 3 1951.889909 651.638 Protein LSM14 homolog A OS=Homo sapiens OX=9606 GN=LSM14A PE=1 SV=3 4.32 3053.1 - 632049 - - - -1.2291 - 2.833 0.502 - 383.2 1 2 1 -0.0024 16 0 0 0 1.59E+07 1.53E+07 - - - 6.8081 1 221125_WJC_METTL3_EV_vs_WT_F06.19110.19110.2 2.99E-12 13/38 R.FSSC[160.03]GGGGGSFGAGGGFGSR.S sp|P04264|K2C1_HUMAN 1 1764.7274 999 87042 19110 2 1764.725943 883.371 "Keratin, type II cytoskeletal 1 OS=Homo sapiens OX=9606 GN=KRT1 PE=1 SV=6" 8.25 3053.4 - 524372 - - - -0.8432 - 3.351 0.741 - 482.6 1 2 0 -0.0015 20 0 0 0 2.07E+07 0.00E+00 - - - 7.4866 0.8553 221125_WJC_METTL3_EV_vs_WT_F06.19112.19112.2 0.0213 14-May F.DYSPPLHK.N "sp|Q9NYF8|BCLF1_HUMAN,tr|E9PKI6|E9PKI6_HUMAN,tr|A0A1W2PQ43|A0A1W2PQ43_HUMAN,tr|E9PK91|E9PK91_HUMAN,tr|E9PK09|E9PK09_HUMAN,tr|E9PQN2|E9PQN2_HUMAN" 6 955.4763 1.42 87044 19112 2 955.478857 478.7454 Bcl-2-associated transcription factor 1 OS=Homo sapiens OX=9606 GN=BCLAF1 PE=1 SV=2 6.74 3053.6 - 373964 - - - 2.6437 - 1.195 0.407 - 72.5 1 1 0 0.0025 8 0 0 0 5.11E+06 3.60E+06 - - - 2.5836 0.9999 221125_WJC_METTL3_EV_vs_WT_F06.19115.19115.3 1.32E-07 16/64 R.DVQGTDASLDEELDR[166.11]VK[136.11].M "sp|Q9UJZ1|STML2_HUMAN,tr|A0A087WYB4|A0A087WYB4_HUMAN" 2 1906.9239 2.18 87045 19115 3 1906.924656 636.6486 "Stomatin-like protein 2, mitochondrial OS=Homo sapiens OX=9606 GN=STOML2 PE=1 SV=1" 3.96 3054 - 1.25E+06 - - - 0.4043 - 2.624 0.527 - 202.4 1 2 1 0.0008 17 0 0 0 2.95E+07 1.35E+07 - - - 6.8524 1 221125_WJC_METTL3_EV_vs_WT_F06.19116.19116.4 1.24E-06 17/96 K.K[136.11]IEVIK[136.11]PGDLGVDLTSK[136.11].L "sp|P38117|ETFB_HUMAN,tr|M0QY67|M0QY67_HUMAN" 2 1835.083 1.85 87046 19116 4 1835.082779 459.778 Electron transfer flavoprotein subunit beta OS=Homo sapiens OX=9606 GN=ETFB PE=1 SV=3 6.12 3054.2 - 957046 - - - -0.1286 - 2.808 0.484 - 212.8 1 2 0 -0.0002 17 0 0 0 5.37E+07 2.91E+07 - - - 3.7971 0.9999 221125_WJC_METTL3_EV_vs_WT_F06.19119.19119.3 5.85E-07 Dec-60 K.FEKDFDFESANAQFNK.E "sp|Q8ND56|LS14A_HUMAN,tr|A0A140TA76|A0A140TA76_HUMAN,tr|K7EMZ9|K7EMZ9_HUMAN" 3 1935.8639 1.04 87049 19119 3 1935.86513 646.2952 Protein LSM14 homolog A OS=Homo sapiens OX=9606 GN=LSM14A PE=1 SV=3 4.32 3054.4 - 945922 - - - 0.6312 - 2.669 0.527 - 249.1 1 2 1 0.0012 16 0 0 0 1.59E+07 1.53E+07 - - - 6.9341 0.9998 221125_WJC_METTL3_EV_vs_WT_F06.19121.19121.3 0.0002 14/60 K.KPEGSWDC[160.03]ELC[160.03]LVQNK.A sp|P49790|NU153_HUMAN 1 1961.8975 0.82 87051 19121 3 1961.899661 654.9731 Nuclear pore complex protein Nup153 OS=Homo sapiens OX=9606 GN=NUP153 PE=1 SV=2 4.68 3054.7 - 608058 - - - 1.0847 - 2.359 0.338 - 158.5 1 2 0 0.0021 16 0 0 0 2.49E+07 3.06E+07 - - - 4.5099 1 221125_WJC_METTL3_EV_vs_WT_F06.19122.19122.3 1.44E-09 16/88 R.K[136.11]VAEPELMGTPDGTC[160.03]YPPPPVPR[166.11].Q "sp|P27708|PYR1_HUMAN,tr|F8VPD4|F8VPD4_HUMAN,tr|H7BZB3|H7BZB3_HUMAN" 3 2525.2413 0.66 87052 19122 3 2525.243622 842.7544 CAD protein OS=Homo sapiens OX=9606 GN=CAD PE=1 SV=3 4.68 3054.8 - 534526 - - - 0.9049 - 3.096 0.609 - 176 1 2 0 0.0023 23 0 0 0 7.10E+06 1.08E+07 - - - 7.9803 0.9994 221125_WJC_METTL3_EV_vs_WT_F06.19123.19123.3 0.00409 Aug-76 R.FSSC[160.03]GGGGGSFGAGGGFGSR.S sp|P04264|K2C1_HUMAN 1 1764.7274 3.61 87053 19123 3 1764.727447 589.2498 "Keratin, type II cytoskeletal 1 OS=Homo sapiens OX=9606 GN=KRT1 PE=1 SV=6" 8.25 3055 - 401463 - - - 0.0091 - 1.362 0.392 - 27.4 1 2 0 0 20 0 0 0 9.02E+06 2.50E+06 - - - 3.6599 1 221125_WJC_METTL3_EV_vs_WT_F06.19127.19127.3 2.31E-05 17/64 K.KIEVIKPGDLGVDLTSK.L "sp|P38117|ETFB_HUMAN,tr|M0QY67|M0QY67_HUMAN" 2 1811.0404 1.91 87055 19127 3 1811.04114 604.6874 Electron transfer flavoprotein subunit beta OS=Homo sapiens OX=9606 GN=ETFB PE=1 SV=3 6.12 3055.4 - 2.08E+06 - - - 0.4003 - 3.186 0.567 - 255.8 1 2 0 0.0007 17 0 0 0 7.05E+07 3.69E+07 - - - 7.7887 1 221125_WJC_METTL3_EV_vs_WT_F06.19128.19128.3 2.64E-11 26/80 K.SADESGQALLAAGHYASDEVR[166.11].E "sp|Q13813|SPTN1_HUMAN,tr|A0A0D9SF54|A0A0D9SF54_HUMAN,tr|A0A0D9SGF6|A0A0D9SGF6_HUMAN" 3 2156.001 1.39 87056 19128 3 2155.995533 719.6743 "Spectrin alpha chain, non-erythrocytic 1 OS=Homo sapiens OX=9606 GN=SPTAN1 PE=1 SV=3" 4.31 3055.5 - 1.23E+06 - - - -2.5172 - 4.82 0.656 - 1148.6 1 2 0 -0.0054 21 0 0 0 1.17E+08 8.47E+07 - - - 9.6229 0.9998 221125_WJC_METTL3_EV_vs_WT_F06.19129.19129.4 8.70E-08 15/96 R.NAEFDR[166.11]HEIQIYEEVAK[136.11].M "sp|Q9NZW5|PALS2_HUMAN,tr|B8ZZG1|B8ZZG1_HUMAN" 2 2108.0294 0.14 87057 19129 4 2108.027109 528.0146 Protein PALS2 OS=Homo sapiens OX=9606 GN=PALS2 PE=1 SV=2 4.57 3055.6 - 961053 - - - -1.0645 - 3.206 0.469 - 240.7 1 2 1 -0.0022 17 0 0 0 1.96E+06 1.35E+07 - - - 3.712 0.9964 221125_WJC_METTL3_EV_vs_WT_F06.19131.19131.3 0.000102 Dec-72 R.VAIHYINPPNPAKDNFTFK.C "sp|P78406|RAE1L_HUMAN,tr|E9PQ57|E9PQ57_HUMAN" 2 2185.132 7.04 87059 19131 3 2185.139519 729.3846 mRNA export factor OS=Homo sapiens OX=9606 GN=RAE1 PE=1 SV=1 8.48 3055.9 - 437989 - - - 3.43 - 2.436 0.368 - 182.1 1 2 1 0.0075 19 0 0 0 4.62E+06 6.57E+05 - - - 4.8282 1 221125_WJC_METTL3_EV_vs_WT_F06.19134.19134.3 1.04E-07 17/56 R.NDNDSWDYTK[136.11]PYLGR[166.11].R "sp|Q8WVV9|HNRLL_HUMAN,tr|V9GYK2|V9GYK2_HUMAN,tr|C9IYN3|C9IYN3_HUMAN,tr|B7WPG3|B7WPG3_HUMAN,tr|H7BXH8|H7BXH8_HUMAN" 5 1860.8398 0.95 87060 19134 3 1860.837491 621.2872 Heterogeneous nuclear ribonucleoprotein L-like OS=Homo sapiens OX=9606 GN=HNRNPLL PE=1 SV=1 4.43 3056.3 - 1.21E+06 - - - -1.2204 - 2.657 0.603 - 319.6 1 2 0 -0.0023 15 0 0 0 1.83E+07 1.93E+07 - - - 7.8121 1 221125_WJC_METTL3_EV_vs_WT_F06.19141.19141.3 4.44E-06 17/48 R.GYFEYIEENK[136.11]YSR[166.11].A "sp|Q00839|HNRPU_HUMAN,tr|Q5RI18|Q5RI18_HUMAN,tr|A0A1W2PP35|A0A1W2PP35_HUMAN,tr|A0A1W2PPS1|A0A1W2PPS1_HUMAN,tr|A0A1W2PRI6|A0A1W2PRI6_HUMAN" 5 1714.7958 3.17 87065 19141 3 1714.795283 572.6059 Heterogeneous nuclear ribonucleoprotein U OS=Homo sapiens OX=9606 GN=HNRNPU PE=1 SV=6 4.79 3057.1 - 4.55E+06 - - - -0.2852 - 3.067 0.614 - 356.2 1 2 1 -0.0005 13 0 0 0 1.94E+08 6.11E+07 - - - 8.4239 0.9999 221125_WJC_METTL3_EV_vs_WT_F06.19142.19142.4 0.000489 12/108 R.GLLQDDAHPTLVTYADHSK[136.11].L "sp|Q86U44|MTA70_HUMAN,tr|F5H6D8|F5H6D8_HUMAN,tr|H0YFV6|H0YFV6_HUMAN,tr|B4DTN4|B4DTN4_HUMAN" 4 2088.0367 0.05 87066 19142 4 2088.03374 523.0165 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 5.13 3057.1 - 3.08E+06 - - - -1.4334 - 2.557 0.44 - 137.3 1 2 0 -0.003 19 0 0 0 3.48E+06 7.47E+07 - - - 3.3725 1 221125_WJC_METTL3_EV_vs_WT_F06.19144.19144.3 1.08E-07 17/92 K.DGAVNGPSVVGDQTPIEPQTSIER.L sp|P49321|NASP_HUMAN 1 2465.2034 1.38 87068 19144 3 2465.198709 822.7417 Nuclear autoantigenic sperm protein OS=Homo sapiens OX=9606 GN=NASP PE=1 SV=2 3.92 3057.4 - 847710 - - - -1.9073 - 3.061 0.569 - 218 1 2 0 -0.0047 24 0 0 0 2.23E+07 1.62E+07 - - - 7.4809 0.9991 221125_WJC_METTL3_EV_vs_WT_F06.19145.19145.3 0.00205 Dec-60 K.LTEDK[136.11]ADVQSIIGLQR[166.11].F "sp|Q13263|TIF1B_HUMAN,tr|M0R0K9|M0R0K9_HUMAN" 2 1802.9857 0.9 87069 19145 3 1802.980455 602.0025 Transcription intermediary factor 1-beta OS=Homo sapiens OX=9606 GN=TRIM28 PE=1 SV=5 4.56 3057.6 - 629810 - - - -2.908 - 2.554 0.43 - 157.9 1 2 1 -0.0052 16 0 0 0 6.74E+06 7.49E+06 - - - 5.7385 1 221125_WJC_METTL3_EV_vs_WT_F06.19146.19146.2 1.05E-08 13/30 K.YFLHDDRDDGVDYWAK.R "sp|Q9NYF8|BCLF1_HUMAN,tr|H0YF14|H0YF14_HUMAN" 2 2013.8857 9.44 87070 19146 2 2013.882346 1007.9501 Bcl-2-associated transcription factor 1 OS=Homo sapiens OX=9606 GN=BCLAF1 PE=1 SV=2 4.28 3057.7 - 331601 - - - -1.6684 - 2.594 0.708 - 354.4 1 2 1 -0.0034 16 0 0 0 5.47E+06 5.79E+05 - - - 6.6127 1 221125_WJC_METTL3_EV_vs_WT_F06.19157.19157.3 3.86E-14 31/80 K.SADESGQALLAAGHYASDEVR.E "sp|Q13813|SPTN1_HUMAN,tr|A0A0D9SF54|A0A0D9SF54_HUMAN,tr|A0A0D9SGF6|A0A0D9SGF6_HUMAN" 3 2145.9927 1.39 87077 19157 3 2145.992464 716.3382 "Spectrin alpha chain, non-erythrocytic 1 OS=Homo sapiens OX=9606 GN=SPTAN1 PE=1 SV=3" 4.31 3059.1 - 7.82E+06 - - - -0.1053 - 5.526 0.707 - 1724.2 1 2 0 -0.0002 21 0 0 0 1.17E+08 8.47E+07 - - - 10.5207 1 221125_WJC_METTL3_EV_vs_WT_F06.19159.19159.3 1.19E-09 17/56 R.NDNDSWDYTKPYLGR.R "sp|Q8WVV9|HNRLL_HUMAN,tr|V9GYK2|V9GYK2_HUMAN,tr|C9IYN3|C9IYN3_HUMAN,tr|B7WPG3|B7WPG3_HUMAN,tr|H7BXH8|H7BXH8_HUMAN" 5 1842.8173 0.9 87079 19159 3 1842.819416 615.2797 Heterogeneous nuclear ribonucleoprotein L-like OS=Homo sapiens OX=9606 GN=HNRNPLL PE=1 SV=1 4.43 3059.4 - 943616 - - - 1.1526 - 2.646 0.602 - 376.5 1 2 0 0.0021 15 0 0 0 1.83E+07 2.04E+07 - - - 7.7902 1 221125_WJC_METTL3_EV_vs_WT_F06.19161.19161.3 3.08E-16 24/92 K.TASNIIDVSAADSQGMEQHEYMDR.A "sp|Q6IAA8|LTOR1_HUMAN,tr|F5GX19|F5GX19_HUMAN,tr|F5H3Y3|F5H3Y3_HUMAN,tr|H0YFI1|H0YFI1_HUMAN,tr|F5H479|F5H479_HUMAN" 5 2667.1541 0.82 87081 19161 3 2667.152569 890.0586 Ragulator complex protein LAMTOR1 OS=Homo sapiens OX=9606 GN=LAMTOR1 PE=1 SV=2 4.1 3059.6 - 638165 - - - -0.5718 - 4.879 0.762 - 969.4 1 2 0 -0.0015 24 0 0 0 5.18E+06 6.35E+06 - - - 10.7163 1 221125_WJC_METTL3_EV_vs_WT_F06.19174.19174.3 2.00E-09 21/108 R.GFGDGYNGYGGGPGGGNFGGSPGYGGGR.G "sp|P22626|ROA2_HUMAN,tr|A0A024RA28|A0A024RA28_HUMAN,tr|A0A7I2V323|A0A7I2V323_HUMAN,tr|A0A7I2V3P7|A0A7I2V3P7_HUMAN" 4 2494.0323 1.5 87092 19174 3 2494.032659 832.3514 Heterogeneous nuclear ribonucleoproteins A2\B1 OS=Homo sapiens OX=9606 GN=HNRNPA2B1 PE=1 SV=2 5.83 3061.2 - 885812 - - - 0.1588 - 3.745 0.683 - 266.3 1 2 0 0.0004 28 0 0 0 2.35E+08 1.57E+08 - - - 9.1925 1 221125_WJC_METTL3_EV_vs_WT_F06.19176.19176.3 5.92E-15 20/92 K.TASNIIDVSAADSQGMEQHEYMDR[166.11].A "sp|Q6IAA8|LTOR1_HUMAN,tr|F5GX19|F5GX19_HUMAN,tr|F5H3Y3|F5H3Y3_HUMAN,tr|H0YFI1|H0YFI1_HUMAN,tr|F5H479|F5H479_HUMAN" 5 2677.1624 0.82 87094 19176 3 2677.158734 893.3947 Ragulator complex protein LAMTOR1 OS=Homo sapiens OX=9606 GN=LAMTOR1 PE=1 SV=2 4.1 3061.5 - 598368 - - - -1.3559 - 4.513 0.743 - 611.1 1 2 0 -0.0036 24 0 0 0 5.18E+06 6.35E+06 - - - 10.3228 1 221125_WJC_METTL3_EV_vs_WT_F06.19177.19177.3 1.96E-09 22/72 R.QGVQVQVSTSNISSLEGAR[166.11].G "sp|P49327|FAS_HUMAN,tr|A0A0U1RQF0|A0A0U1RQF0_HUMAN" 2 1969.0104 0.62 87095 19177 3 1969.01518 657.3441 Fatty acid synthase OS=Homo sapiens OX=9606 GN=FASN PE=1 SV=3 6 3061.6 - 530181 - - - 2.4266 - 4.171 0.547 - 483.2 1 2 0 0.0048 19 0 0 0 1.41E+07 2.28E+07 - - - 8.1459 0.9999 221125_WJC_METTL3_EV_vs_WT_F06.19182.19182.3 5.18E-10 20/80 K.AENNSEVGASGYGVPGPTWDR[166.11].G sp|Q08211|DHX9_HUMAN 1 2171.9747 1.2 87098 19182 3 2171.967284 724.9989 ATP-dependent RNA helicase A OS=Homo sapiens OX=9606 GN=DHX9 PE=1 SV=4 4.14 3062.1 - 845870 - - - -3.4351 - 3.192 0.584 - 204.1 1 2 0 -0.0075 21 0 0 0 3.65E+07 3.04E+07 - - - 7.8316 1 221125_WJC_METTL3_EV_vs_WT_F06.19184.19184.3 5.00E-15 26/108 R.GFGDGYNGYGGGPGGGNFGGSPGYGGGR[166.11].G "sp|P22626|ROA2_HUMAN,tr|A0A024RA28|A0A024RA28_HUMAN,tr|A0A7I2V323|A0A7I2V323_HUMAN,tr|A0A7I2V3P7|A0A7I2V3P7_HUMAN" 4 2504.0405 1.5 87100 19184 3 2504.039727 835.6875 Heterogeneous nuclear ribonucleoproteins A2\B1 OS=Homo sapiens OX=9606 GN=HNRNPA2B1 PE=1 SV=2 5.83 3062.3 - 2.59E+06 - - - -0.3219 - 4.484 0.654 - 459.2 1 2 0 -0.0008 28 0 0 0 2.35E+08 1.57E+08 - - - 9.2834 1 221125_WJC_METTL3_EV_vs_WT_F06.19185.19185.3 1.34E-15 27/84 K.VIAINVDDPDAANYNDINDVK[136.11]R[166.11].L sp|Q15181|IPYR_HUMAN 1 2461.2204 0.57 87101 19185 3 2461.215987 821.4141 Inorganic pyrophosphatase OS=Homo sapiens OX=9606 GN=PPA1 PE=1 SV=2 3.97 3062.4 - 1.24E+06 - - - -1.7938 - 4.876 0.708 - 874.4 1 2 0 -0.0044 22 0 0 0 1.28E+07 2.26E+07 - - - 10.1885 1 221125_WJC_METTL3_EV_vs_WT_F06.19186.19186.3 6.29E-07 14/60 K.TGEEIFGTIGMR[166.11]PNAK[136.11].N "sp|Q99873|ANM1_HUMAN,tr|E9PKG1|E9PKG1_HUMAN" 2 1737.8839 1.78 87102 19186 3 1737.886582 580.3019 Protein arginine N-methyltransferase 1 OS=Homo sapiens OX=9606 GN=PRMT1 PE=1 SV=3 5.81 3062.6 - 621159 - - - 1.5576 - 2.987 0.497 - 196.8 1 2 0 0.0027 16 0 0 0 1.31E+07 7.36E+06 - - - 6.8881 0.9999 221125_WJC_METTL3_EV_vs_WT_F06.19192.19192.4 5.00E-08 15/108 R.SVDVILDDDLVDKAKPGDR.V "sp|P25205|MCM3_HUMAN,tr|J3KQ69|J3KQ69_HUMAN,tr|A0A499FHX9|A0A499FHX9_HUMAN" 3 2069.0641 0.52 87106 19192 4 2069.066285 518.2733 DNA replication licensing factor MCM3 OS=Homo sapiens OX=9606 GN=MCM3 PE=1 SV=3 4.11 3063.3 - 563806 - - - 1.0734 - 3.166 0.544 - 122.4 1 2 1 0.0022 19 0 0 0 4.72E+06 9.07E+06 - - - 4.3502 0.9999 221125_WJC_METTL3_EV_vs_WT_F06.19193.19193.4 2.47E-10 19/96 R.C[160.03]IKDEETGLC[160.03]LLPLKEK.K sp|P15924|DESP_HUMAN 1 2045.0537 277.94 87107 19193 4 2045.053851 512.2707 Desmoplakin OS=Homo sapiens OX=9606 GN=DSP PE=1 SV=3 4.87 3063.3 - 1.15E+06 - - - 0.0738 - 3.35 0.605 - 262.1 1 2 2 0.0002 17 0 0 0 2.69E+07 9.67E+04 - - - 4.9116 1 221125_WJC_METTL3_EV_vs_WT_F06.19197.19197.2 2.66E-12 21/54 R.GFGDGYNGYGGGPGGGNFGGSPGYGGGR.G "sp|P22626|ROA2_HUMAN,tr|A0A024RA28|A0A024RA28_HUMAN,tr|A0A7I2V323|A0A7I2V323_HUMAN,tr|A0A7I2V3P7|A0A7I2V3P7_HUMAN" 4 2494.0323 1.68 87111 19197 2 2494.031571 1248.0234 Heterogeneous nuclear ribonucleoproteins A2\B1 OS=Homo sapiens OX=9606 GN=HNRNPA2B1 PE=1 SV=2 5.83 3063.8 - 746326 - - - -0.2775 - 4.326 0.782 - 620.2 1 2 0 -0.0007 28 0 0 0 3.06E+07 1.82E+07 - - - 8.4175 0.9999 221125_WJC_METTL3_EV_vs_WT_F06.19198.19198.3 1.62E-06 Dec-76 K.YQGDGIVEDEEETMENNEEK.K "sp|Q9NYF8|BCLF1_HUMAN,tr|H0YF63|H0YF63_HUMAN,tr|E9PK91|E9PK91_HUMAN,tr|H0YF14|H0YF14_HUMAN" 4 2356.9489 9.61 87112 19198 3 2356.94294 786.6569 Bcl-2-associated transcription factor 1 OS=Homo sapiens OX=9606 GN=BCLAF1 PE=1 SV=2 3.62 3063.9 - 680840 - - - -2.5266 - 2.994 0.443 - 184.2 1 2 0 -0.006 20 0 0 0 7.56E+06 7.87E+05 - - - 6.1378 1 221125_WJC_METTL3_EV_vs_WT_F06.19201.19201.3 1.05E-06 19/72 K.SIQTPQSHGTLTAELWDNK.V "sp|Q9Y520|PRC2C_HUMAN,tr|E7EPN9|E7EPN9_HUMAN,tr|H7C5N8|H7C5N8_HUMAN,tr|A0A2R8Y7F4|A0A2R8Y7F4_HUMAN,tr|A0A2R8YET2|A0A2R8YET2_HUMAN" 5 2125.044 6.41 87113 19201 3 2125.047405 709.3553 Protein PRRC2C OS=Homo sapiens OX=9606 GN=PRRC2C PE=1 SV=4 5.3 3064.3 - 3.72E+06 - - - 1.6037 - 3.593 0.566 - 236.1 1 2 0 0.0034 19 0 0 0 1.99E+08 3.11E+07 - - - 7.9916 1 221125_WJC_METTL3_EV_vs_WT_F06.19202.19202.3 2.65E-08 28/84 K.VIAINVDDPDAANYNDINDVKR.L sp|Q15181|IPYR_HUMAN 1 2443.1979 0.57 87114 19202 3 2443.199004 815.4066 Inorganic pyrophosphatase OS=Homo sapiens OX=9606 GN=PPA1 PE=1 SV=2 3.97 3064.5 - 1.35E+06 - - - 0.4388 - 4.758 0.691 - 1031.8 1 2 0 0.0011 22 0 0 0 1.28E+07 2.26E+07 - - - 9.9418 1 221125_WJC_METTL3_EV_vs_WT_F06.19203.19203.3 2.58E-08 23/80 K.AENNSEVGASGYGVPGPTWDR.G sp|Q08211|DHX9_HUMAN 1 2161.9665 1.19 87115 19203 3 2161.966466 721.6628 ATP-dependent RNA helicase A OS=Homo sapiens OX=9606 GN=DHX9 PE=1 SV=4 4.14 3064.5 - 1.92E+06 - - - -0.0042 - 3.549 0.58 - 332.4 1 2 0 0 21 0 0 0 3.66E+07 3.07E+07 - - - 8.0432 1 221125_WJC_METTL3_EV_vs_WT_F06.19204.19204.3 6.21E-08 20/72 R.QGVQVQVSTSNISSLEGAR.G "sp|P49327|FAS_HUMAN,tr|A0A0U1RQF0|A0A0U1RQF0_HUMAN" 2 1959.0021 0.62 87116 19204 3 1959.004311 654.008 Fatty acid synthase OS=Homo sapiens OX=9606 GN=FASN PE=1 SV=3 6 3064.6 - 1.19E+06 - - - 1.1123 - 3.722 0.587 - 424 1 2 0 0.0022 19 0 0 0 1.41E+07 2.29E+07 - - - 8.3127 1 221125_WJC_METTL3_EV_vs_WT_F06.19205.19205.2 1.13E-10 18/36 R.QGVQVQVSTSNISSLEGAR[166.11].G "sp|P49327|FAS_HUMAN,tr|A0A0U1RQF0|A0A0U1RQF0_HUMAN" 2 1969.0104 0.54 87117 19205 2 1969.009892 985.5125 Fatty acid synthase OS=Homo sapiens OX=9606 GN=FASN PE=1 SV=3 6 3064.8 - 774070 - - - -0.259 - 3.465 0.656 - 798.3 1 2 0 -0.0005 19 0 0 0 5.42E+06 9.95E+06 - - - 6.9413 1 221125_WJC_METTL3_EV_vs_WT_F06.19208.19208.4 5.71E-09 23/120 K.ATGEADVHFETHEDAVAAMLK.D "sp|Q12849|GRSF1_HUMAN,tr|H0YAK1|H0YAK1_HUMAN,tr|H0Y8R1|H0Y8R1_HUMAN,tr|F5H5I6|F5H5I6_HUMAN" 4 2241.0372 1.71 87120 19208 4 2241.042196 561.2666 G-rich sequence factor 1 OS=Homo sapiens OX=9606 GN=GRSF1 PE=1 SV=3 4.49 3065.2 - 489758 - - - 2.2307 - 4.331 0.582 - 359 1 2 0 0.005 21 0 0 0 1.73E+07 1.01E+07 - - - 4.775 1 221125_WJC_METTL3_EV_vs_WT_F06.19209.19209.2 2.03E-11 18/36 R.QGVQVQVSTSNISSLEGAR.G "sp|P49327|FAS_HUMAN,tr|A0A0U1RQF0|A0A0U1RQF0_HUMAN" 2 1959.0021 0.54 87121 19209 2 1959.00239 980.5083 Fatty acid synthase OS=Homo sapiens OX=9606 GN=FASN PE=1 SV=3 6 3065.3 - 477850 - - - 0.1317 - 3.537 0.699 - 901.8 1 2 0 0.0003 19 0 0 0 5.42E+06 9.95E+06 - - - 7.3096 0.9996 221125_WJC_METTL3_EV_vs_WT_F06.19213.19213.4 0.136 Oct-90 K.YFLHDDRDDGVDYWAK.R "sp|Q9NYF8|BCLF1_HUMAN,tr|H0YF14|H0YF14_HUMAN" 2 2013.8857 2.22 87124 19213 4 2013.888217 504.4787 Bcl-2-associated transcription factor 1 OS=Homo sapiens OX=9606 GN=BCLAF1 PE=1 SV=2 4.28 3065.8 - 2.45E+06 - - - 1.2468 - 2.222 0.431 - 70.1 1 2 1 0.0025 16 0 0 0 4.07E+08 1.83E+08 - - - 3.258 1 221125_WJC_METTL3_EV_vs_WT_F06.19215.19215.3 2.30E-11 18/88 K.SSGASSESVQTVNQAEVESLTVK[136.11].S "sp|Q8N573|OXR1_HUMAN,tr|H0YC07|H0YC07_HUMAN" 2 2344.1485 0.8 87125 19215 3 2344.148428 782.3901 Oxidation resistance protein 1 OS=Homo sapiens OX=9606 GN=OXR1 PE=1 SV=2 4.25 3066 - 1.64E+06 - - - -0.0427 - 3.784 0.62 - 509.5 1 2 0 -0.0001 23 0 0 0 1.48E+07 1.83E+07 - - - 8.5743 1 221125_WJC_METTL3_EV_vs_WT_F06.19217.19217.3 3.63E-12 19/88 K.SSGASSESVQTVNQAEVESLTVK.S "sp|Q8N573|OXR1_HUMAN,tr|H0YC07|H0YC07_HUMAN" 2 2336.1343 0.79 87127 19217 3 2336.133918 779.7187 Oxidation resistance protein 1 OS=Homo sapiens OX=9606 GN=OXR1 PE=1 SV=2 4.25 3066.2 - 1.75E+06 - - - -0.1755 - 3.703 0.668 - 520.8 1 2 0 -0.0004 23 0 0 0 1.46E+07 1.83E+07 - - - 9.0586 1 221125_WJC_METTL3_EV_vs_WT_F06.19220.19220.3 1.58E-09 28/100 K.NGFSSVQATQLQTTQSVEGATGSAVK[136.11].S "sp|Q14157|UBP2L_HUMAN,tr|F8W726|F8W726_HUMAN" 2 2603.2918 2.2 87130 19220 3 2603.294235 868.7712 Ubiquitin-associated protein 2-like OS=Homo sapiens OX=9606 GN=UBAP2L PE=1 SV=2 6 3066.6 - 1.28E+06 - - - 0.9204 - 4.459 0.663 - 874.4 1 2 0 0.0024 26 0 0 0 7.87E+08 3.57E+08 - - - 9.3704 1 221125_WJC_METTL3_EV_vs_WT_F06.19222.19222.3 0.00145 14/68 K.SIEIPR[166.11]PVDGVEVPGC[160.03]GK[136.11].L "sp|P26368|U2AF2_HUMAN,tr|K7ENG2|K7ENG2_HUMAN" 2 1926 0.83 87132 19222 3 1926.000104 643.0073 Splicing factor U2AF 65 kDa subunit OS=Homo sapiens OX=9606 GN=U2AF2 PE=1 SV=4 4.68 3066.7 - 1.09E+06 - - - 0.0706 - 2.536 0.521 - 152 1 2 0 0.0001 18 0 0 0 1.40E+07 1.68E+07 - - - 6.6659 1 221125_WJC_METTL3_EV_vs_WT_F06.19223.19223.2 9.46E-12 19/40 K.AENNSEVGASGYGVPGPTWDR[166.11].G sp|Q08211|DHX9_HUMAN 1 2171.9747 1.36 87133 19223 2 2171.97455 1086.9946 ATP-dependent RNA helicase A OS=Homo sapiens OX=9606 GN=DHX9 PE=1 SV=4 4.14 3066.9 - 799740 - - - -0.0898 - 3.265 0.733 - 535 1 2 0 -0.0002 21 0 0 0 1.40E+07 1.03E+07 - - - 7.364 1 221125_WJC_METTL3_EV_vs_WT_F06.19225.19225.2 4.55E-15 22/40 K.AENNSEVGASGYGVPGPTWDR.G sp|Q08211|DHX9_HUMAN 1 2161.9665 1.36 87135 19225 2 2161.963881 1081.9905 ATP-dependent RNA helicase A OS=Homo sapiens OX=9606 GN=DHX9 PE=1 SV=4 4.14 3067.1 - 709934 - - - -1.1998 - 4.105 0.768 - 789.9 1 2 0 -0.0026 21 0 0 0 1.40E+07 1.03E+07 - - - 8.1846 1 221125_WJC_METTL3_EV_vs_WT_F06.19230.19230.3 1.02E-05 22/76 K.TTQFSC[160.03]TLGEKFEETTADGR.K "sp|Q01469|FABP5_HUMAN,tr|I6L8B7|I6L8B7_HUMAN" 2 2277.0219 113.04 87139 19230 3 2277.024354 760.0146 Fatty acid-binding protein 5 OS=Homo sapiens OX=9606 GN=FABP5 PE=1 SV=3 4.41 3067.7 - 2.10E+06 - - - 1.0597 - 4.343 0.609 - 560.1 1 2 1 0.0024 20 0 0 0 2.40E+07 2.13E+05 - - - 8.8919 1 221125_WJC_METTL3_EV_vs_WT_F06.19234.19234.2 1.07E-20 28/54 R.GFGDGYNGYGGGPGGGNFGGSPGYGGGR[166.11].G "sp|P22626|ROA2_HUMAN,tr|A0A024RA28|A0A024RA28_HUMAN,tr|A0A7I2V323|A0A7I2V323_HUMAN,tr|A0A7I2V3P7|A0A7I2V3P7_HUMAN" 4 2504.0405 1.68 87142 19234 2 2504.041885 1253.0275 Heterogeneous nuclear ribonucleoproteins A2\B1 OS=Homo sapiens OX=9606 GN=HNRNPA2B1 PE=1 SV=2 5.83 3068.2 - 1.69E+06 - - - 0.5399 - 4.671 0.748 - 1355 1 2 0 0.0014 28 0 0 0 3.06E+07 1.82E+07 - - - 8.3548 0.9998 221125_WJC_METTL3_EV_vs_WT_F06.19235.19235.4 1.19E-11 20/120 K.ATGEADVHFETHEDAVAAMLK[136.11].D "sp|Q12849|GRSF1_HUMAN,tr|H0YAK1|H0YAK1_HUMAN,tr|H0Y8R1|H0Y8R1_HUMAN,tr|F5H5I6|F5H5I6_HUMAN" 4 2249.0514 1.69 87143 19235 4 2249.062349 563.2701 G-rich sequence factor 1 OS=Homo sapiens OX=9606 GN=GRSF1 PE=1 SV=3 4.49 3068.3 - 1.62E+06 - - - 4.8696 - 3.605 0.588 - 230.5 1 2 0 0.011 21 0 0 0 1.71E+07 1.01E+07 - - - 4.7649 0.9972 221125_WJC_METTL3_EV_vs_WT_F06.19242.19242.4 0.000765 Nov-90 R.DYQGPLKEHEVTIFVR.R "sp|P53396|ACLY_HUMAN,tr|K7EIE7|K7EIE7_HUMAN" 2 1929.9949 0.38 87150 19242 4 1929.998752 483.506 ATP-citrate synthase OS=Homo sapiens OX=9606 GN=ACLY PE=1 SV=3 5.45 3069 - 325976 - - - 2.0155 - 2.121 0.336 - 79.1 1 2 1 0.0039 16 0 0 0 3.38E+06 8.91E+06 - - - 2.4143 1 221125_WJC_METTL3_EV_vs_WT_F06.19243.19243.2 9.08E-09 18/50 K.NGFSSVQATQLQTTQSVEGATGSAVK[136.11].S "sp|Q14157|UBP2L_HUMAN,tr|F8W726|F8W726_HUMAN" 2 2603.2918 2.28 87151 19243 2 2603.288356 1302.6532 Ubiquitin-associated protein 2-like OS=Homo sapiens OX=9606 GN=UBAP2L PE=1 SV=2 6 3069.2 - 217512 - - - -1.3379 - 3.566 0.684 - 733.5 1 2 0 -0.0035 26 0 0 0 2.74E+07 1.20E+07 - - - 7.2178 1 221125_WJC_METTL3_EV_vs_WT_F06.19244.19244.2 0.00105 18/38 K.YQGDGIVEDEEETMENNEEK.K "sp|Q9NYF8|BCLF1_HUMAN,tr|H0YF63|H0YF63_HUMAN,tr|E9PK91|E9PK91_HUMAN,tr|H0YF14|H0YF14_HUMAN" 4 2356.9489 2.85 87152 19244 2 2356.947304 1179.4817 Bcl-2-associated transcription factor 1 OS=Homo sapiens OX=9606 GN=BCLAF1 PE=1 SV=2 3.62 3069.3 - 209395 - - - -0.675 - 3.724 0.739 - 1150.1 1 2 0 -0.0016 20 0 0 0 5.18E+07 1.82E+07 - - - 7.7312 1 221125_WJC_METTL3_EV_vs_WT_F06.19247.19247.4 1.73E-10 25/150 K.NGFSSVQATQLQTTQSVEGATGSAVK.S "sp|Q14157|UBP2L_HUMAN,tr|F8W726|F8W726_HUMAN" 2 2595.2776 2.52 87153 19247 4 2595.277393 649.8267 Ubiquitin-associated protein 2-like OS=Homo sapiens OX=9606 GN=UBAP2L PE=1 SV=2 6 3069.7 - 2.57E+06 - - - -0.0948 - 3.902 0.565 - 303.4 1 2 0 -0.0002 26 0 0 0 3.69E+07 1.46E+07 - - - 4.5732 0.9999 221125_WJC_METTL3_EV_vs_WT_F06.19248.19248.4 2.20E-07 18/138 K.LYAVHQEGNK[136.11]NVGLDIEAEVPAVK[136.11].D "sp|P50990|TCPQ_HUMAN,tr|H7C2U0|H7C2U0_HUMAN" 2 2608.3832 0.37 87154 19248 4 2608.387618 653.1031 T-complex protein 1 subunit theta OS=Homo sapiens OX=9606 GN=CCT8 PE=1 SV=4 4.83 3069.8 - 2.03E+06 - - - 1.7064 - 3.232 0.524 - 129.9 1 2 1 0.0045 24 0 0 0 4.95E+07 1.35E+08 - - - 4.1622 1 221125_WJC_METTL3_EV_vs_WT_F06.19250.19250.3 2.18E-09 18/76 R.TQQAAQANITLQEQIEAIHK[136.11].A "sp|Q15459|SF3A1_HUMAN,tr|H7C1L2|H7C1L2_HUMAN" 2 2242.1797 1.03 87156 19250 3 2242.175532 748.4005 Splicing factor 3A subunit 1 OS=Homo sapiens OX=9606 GN=SF3A1 PE=1 SV=1 5.37 3070 - 1.33E+06 - - - -1.8629 - 3.824 0.533 - 421.2 1 2 0 -0.0042 20 0 0 0 7.32E+07 7.10E+07 - - - 7.7353 1 221125_WJC_METTL3_EV_vs_WT_F06.19251.19251.3 3.83E-10 21/76 R.TQQAAQANITLQEQIEAIHK.A "sp|Q15459|SF3A1_HUMAN,tr|H7C1L2|H7C1L2_HUMAN" 2 2234.1655 1.05 87157 19251 3 2234.168682 745.7291 Splicing factor 3A subunit 1 OS=Homo sapiens OX=9606 GN=SF3A1 PE=1 SV=1 5.37 3070.1 - 1.15E+06 - - - 1.4202 - 4.204 0.571 - 436.8 1 2 0 0.0032 20 0 0 0 7.44E+07 7.10E+07 - - - 8.3891 1 221125_WJC_METTL3_EV_vs_WT_F06.19252.19252.2 2.05E-19 25/50 K.NGFSSVQATQLQTTQSVEGATGSAVK.S "sp|Q14157|UBP2L_HUMAN,tr|F8W726|F8W726_HUMAN" 2 2595.2776 2.28 87158 19252 2 2595.277381 1298.6461 Ubiquitin-associated protein 2-like OS=Homo sapiens OX=9606 GN=UBAP2L PE=1 SV=2 6 3070.3 - 1.13E+06 - - - -0.0994 - 4.935 0.74 - 1753.7 1 2 0 -0.0003 26 0 0 0 2.74E+07 1.20E+07 - - - 8.4313 0.9999 221125_WJC_METTL3_EV_vs_WT_F06.19255.19255.3 1.83E-05 21/56 K.VGEVIVTK[136.11]DDAMLLK[136.11].G "sp|P10809|CH60_HUMAN,tr|A0A7I2V2X6|A0A7I2V2X6_HUMAN,tr|A0A7I2YQK6|A0A7I2YQK6_HUMAN,tr|A0A7I2V599|A0A7I2V599_HUMAN" 4 1645.9295 2.06 87161 19255 3 1645.93097 549.6505 "60 kDa heat shock protein, mitochondrial OS=Homo sapiens OX=9606 GN=HSPD1 PE=1 SV=2" 4.56 3070.6 - 782121 - - - 0.8658 - 4.126 0.431 - 652 1 2 1 0.0014 15 0 0 0 1.69E+07 8.19E+06 - - - 7.0431 1 221125_WJC_METTL3_EV_vs_WT_F06.19258.19258.3 9.07E-07 17/68 K.K[136.11]GVNLPGAAVDLPAVSEK[136.11].D "sp|P14618|KPYM_HUMAN,tr|H3BQ34|H3BQ34_HUMAN,tr|B4DNK4|B4DNK4_HUMAN,tr|A0A804F6T5|A0A804F6T5_HUMAN,tr|H3BTN5|H3BTN5_HUMAN,tr|H3BR70|H3BR70_HUMAN,tr|A0A804F729|A0A804F729_HUMAN" 7 1780.0065 2.1 87164 19258 3 1780.006411 594.3428 Pyruvate kinase PKM OS=Homo sapiens OX=9606 GN=PKM PE=1 SV=4 6.07 3071 - 413418 - - - -0.0775 - 3.243 0.528 - 339.3 1 2 0 -0.0001 18 0 0 0 1.37E+07 6.50E+06 - - - 7.3562 0.9994 221125_WJC_METTL3_EV_vs_WT_F06.19259.19259.4 0.00152 14/84 R.EVVNK[136.11]DVLDVYIEHR[166.11].L sp|P33993|MCM7_HUMAN 1 1844.9751 1.05 87165 19259 4 1844.970865 462.2511 DNA replication licensing factor MCM7 OS=Homo sapiens OX=9606 GN=MCM7 PE=1 SV=4 4.75 3071.2 - 358168 - - - -2.3133 - 2.434 0.438 - 190 1 2 1 -0.0043 15 0 0 0 3.03E+06 2.89E+06 - - - 3.3555 0.9873 221125_WJC_METTL3_EV_vs_WT_F06.19260.19260.3 3.91E-05 Dec-44 D.GIHLLDPDVVAR[166.11].F sp|Q86U44|MTA70_HUMAN 1 1313.7331 0.02 87166 19260 3 1313.735007 438.9183 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 5.21 3071.3 - 267864 - - - 1.4478 - 2.532 0.377 - 334.9 1 1 0 0.0019 12 0 0 0 1.00E+05 4.03E+06 - - - 5.3177 0.9999 221125_WJC_METTL3_EV_vs_WT_F06.19263.19263.3 7.23E-06 Dec-52 K.K[136.11]K[136.11]PLDGEYFTLQIR[166.11].G "sp|P04637|P53_HUMAN,tr|A0A087X1Q1|A0A087X1Q1_HUMAN,tr|A0A0U1RQC9|A0A0U1RQC9_HUMAN" 3 1732.9722 1.08 87167 19263 3 1732.971729 578.6647 Cellular tumor antigen p53 OS=Homo sapiens OX=9606 GN=TP53 PE=1 SV=4 8.5 3071.7 - 1.29E+06 - - - -0.2868 - 2.312 0.413 - 213 1 2 0 -0.0005 14 0 0 0 3.23E+07 3.00E+07 - - - 5.3717 1 221125_WJC_METTL3_EV_vs_WT_F06.19266.19266.4 9.84E-10 25/132 K.SAMAHDPISPVLSDPHLDAVDQR.L sp|O75063|XYLK_HUMAN 1 2470.1911 1.55 87170 19266 4 2470.192198 618.555 Glycosaminoglycan xylosylkinase OS=Homo sapiens OX=9606 GN=FAM20B PE=1 SV=1 4.54 3072.1 - 867271 - - - 0.4558 - 4.572 0.627 - 390.3 1 2 0 0.0011 23 0 0 0 9.02E+06 5.84E+06 - - - 5.1755 1 221125_WJC_METTL3_EV_vs_WT_F06.19267.19267.3 6.78E-07 17/52 K.KKPLDGEYFTLQIR.G "sp|P04637|P53_HUMAN,tr|A0A087X1Q1|A0A087X1Q1_HUMAN,tr|A0A0U1RQC9|A0A0U1RQC9_HUMAN" 3 1706.9356 1.08 87171 19267 3 1706.938839 569.9858 Cellular tumor antigen p53 OS=Homo sapiens OX=9606 GN=TP53 PE=1 SV=4 8.5 3072.2 - 809435 - - - 1.9233 - 2.815 0.502 - 396.8 1 2 0 0.0033 14 0 0 0 3.25E+07 3.01E+07 - - - 6.8863 0.9996 221125_WJC_METTL3_EV_vs_WT_F06.19270.19270.4 3.93E-05 13/102 K.EIEGEEIEIVLAK[136.11]PPDK[136.11]K[136.11].R "sp|O43390|HNRPR_HUMAN,tr|B4DT28|B4DT28_HUMAN,tr|A0A6Q8PH35|A0A6Q8PH35_HUMAN,tr|A0A286YEZ8|A0A286YEZ8_HUMAN" 4 2060.1467 1.56 87174 19270 4 2060.150568 516.044 Heterogeneous nuclear ribonucleoprotein R OS=Homo sapiens OX=9606 GN=HNRNPR PE=1 SV=1 4.42 3072.6 - 515888 - - - 1.8591 - 2.396 0.357 - 113.3 1 2 0 0.0038 18 0 0 0 2.97E+08 1.90E+08 - - - 2.6316 0.9999 221125_WJC_METTL3_EV_vs_WT_F06.19278.19278.3 6.83E-11 17/72 K.IVGC[160.03]SVHKGFAFVQYVNER.N "sp|P07910|HNRPC_HUMAN,tr|G3V251|G3V251_HUMAN,tr|B4DY08|B4DY08_HUMAN,tr|G3V575|G3V575_HUMAN,tr|B4DSU6|B4DSU6_HUMAN,tr|G3V3K6|G3V3K6_HUMAN,tr|B2R5W2|B2R5W2_HUMAN,tr|G3V4C1|G3V4C1_HUMAN,tr|G3V576|G3V576_HUMAN,tr|G3V5X6|G3V5X6_HUMAN,tr|G3V4W0|G3V4W0_HUMAN,tr|G3V555|G3V555_HUMAN,tr|G3V4M8|G3V4M8_HUMAN,tr|G3V2Q1|G3V2Q1_HUMAN" 14 2209.1102 2.18 87180 19278 3 2209.115974 737.3774 Heterogeneous nuclear ribonucleoproteins C1\C2 OS=Homo sapiens OX=9606 GN=HNRNPC PE=1 SV=4 8.21 3073.5 - 683562 - - - 2.5943 - 3.387 0.608 - 327.4 1 2 1 0.0057 19 0 0 0 7.18E+06 3.29E+06 - - - 8.3142 0.997 221125_WJC_METTL3_EV_vs_WT_F06.19283.19283.4 0.00483 Aug-78 K.EKDLSWSEHLFAPK.E "sp|Q5VT06|CE350_HUMAN,tr|H0Y7F7|H0Y7F7_HUMAN" 2 1685.8413 2.65 87185 19283 4 1685.840549 422.4676 Centrosome-associated protein 350 OS=Homo sapiens OX=9606 GN=CEP350 PE=1 SV=1 5.45 3074.1 - 242350 - - - -0.4585 - 1.747 0.315 - 49.3 1 2 1 -0.0008 14 0 0 0 5.47E+06 2.07E+06 - - - 2.1706 0.9999 221125_WJC_METTL3_EV_vs_WT_F06.19285.19285.4 7.65E-08 21/150 R.TLVNKEEPPKELPAAEPVLSPLEGTK.M "sp|Q9BY77|PDIP3_HUMAN,tr|F6VRR5|F6VRR5_HUMAN" 2 2785.5113 1.75 87186 19285 4 2785.513662 697.3851 Polymerase delta-interacting protein 3 OS=Homo sapiens OX=9606 GN=POLDIP3 PE=1 SV=2 4.65 3074.3 - 8.54E+06 - - - 0.8383 - 3.497 0.582 - 265.3 1 2 2 0.0023 26 0 0 0 1.39E+09 7.95E+08 - - - 4.686 0.9999 221125_WJC_METTL3_EV_vs_WT_F06.19286.19286.4 2.23E-05 22/150 R.TLVNK[136.11]EEPPK[136.11]ELPAAEPVLSPLEGTK[136.11].M "sp|Q9BY77|PDIP3_HUMAN,tr|F6VRR5|F6VRR5_HUMAN" 2 2809.5539 1.75 87187 19286 4 2809.555359 703.3958 Polymerase delta-interacting protein 3 OS=Homo sapiens OX=9606 GN=POLDIP3 PE=1 SV=2 4.65 3074.4 - 4.36E+06 - - - 0.5097 - 3.66 0.584 - 304.1 1 2 2 0.0014 26 0 0 0 1.39E+09 7.95E+08 - - - 4.718 1 221125_WJC_METTL3_EV_vs_WT_F06.19288.19288.2 4.67E-10 18/38 K.YQGDGIVEDEEETMENNEEK[136.11].K "sp|Q9NYF8|BCLF1_HUMAN,tr|H0YF63|H0YF63_HUMAN,tr|E9PK91|E9PK91_HUMAN,tr|H0YF14|H0YF14_HUMAN" 4 2364.9631 2.84 87189 19288 2 2364.959494 1183.4888 Bcl-2-associated transcription factor 1 OS=Homo sapiens OX=9606 GN=BCLAF1 PE=1 SV=2 3.62 3074.6 - 1.64E+06 - - - -1.5226 - 3.475 0.791 - 1048 1 2 0 -0.0036 20 0 0 0 5.17E+07 1.82E+07 - - - 7.9445 0.9999 221125_WJC_METTL3_EV_vs_WT_F06.19290.19290.4 0.000646 15/78 K.KKPLDGEYFTLQIR.G "sp|P04637|P53_HUMAN,tr|A0A087X1Q1|A0A087X1Q1_HUMAN,tr|A0A0U1RQC9|A0A0U1RQC9_HUMAN" 3 1706.9356 1.17 87191 19290 4 1706.935156 427.7412 Cellular tumor antigen p53 OS=Homo sapiens OX=9606 GN=TP53 PE=1 SV=4 8.5 3074.9 - 808098 - - - -0.2343 - 2.239 0.442 - 156.5 1 2 0 -0.0004 14 0 0 0 1.54E+07 1.31E+07 - - - 3.3664 0.9967 221125_WJC_METTL3_EV_vs_WT_F06.19291.19291.4 0.00686 11/108 K.IVGC[160.03]SVHKGFAFVQYVNER.N "sp|P07910|HNRPC_HUMAN,tr|G3V251|G3V251_HUMAN,tr|B4DY08|B4DY08_HUMAN,tr|G3V575|G3V575_HUMAN,tr|B4DSU6|B4DSU6_HUMAN,tr|G3V3K6|G3V3K6_HUMAN,tr|B2R5W2|B2R5W2_HUMAN,tr|G3V4C1|G3V4C1_HUMAN,tr|G3V576|G3V576_HUMAN,tr|G3V5X6|G3V5X6_HUMAN,tr|G3V4W0|G3V4W0_HUMAN,tr|G3V555|G3V555_HUMAN,tr|G3V4M8|G3V4M8_HUMAN,tr|G3V2Q1|G3V2Q1_HUMAN" 14 2209.1102 1.34 87192 19291 4 2209.109871 553.2848 Heterogeneous nuclear ribonucleoproteins C1\C2 OS=Homo sapiens OX=9606 GN=HNRNPC PE=1 SV=4 8.21 3075 - 783359 - - - -0.1684 - 1.983 0.307 - 67 1 2 1 -0.0004 19 0 0 0 9.29E+06 6.91E+06 - - - 2.1296 0.9996 221125_WJC_METTL3_EV_vs_WT_F06.19300.19300.4 0.066 16/138 K.GVTIPYRPKPSSSPVIFAGGQLTK.L "tr|F8VZX2|F8VZX2_HUMAN,tr|H3BRU6|H3BRU6_HUMAN" 2 2499.3849 1.15 87199 19300 4 2499.38747 625.8535 Poly(rC)-binding protein 2 OS=Homo sapiens OX=9606 GN=PCBP2 PE=1 SV=1 10.29 3076.1 - 1.10E+06 - - - 1.0102 - 2.506 0.334 - 132.6 1 2 0 0.0025 24 0 0 0 2.22E+07 1.93E+07 - - - 2.4273 1 221125_WJC_METTL3_EV_vs_WT_F06.19301.19301.3 5.33E-08 22/100 R.TLVNKEEPPKELPAAEPVLSPLEGTK.M "sp|Q9BY77|PDIP3_HUMAN,tr|F6VRR5|F6VRR5_HUMAN" 2 2785.5113 1.78 87200 19301 3 2785.513921 929.5111 Polymerase delta-interacting protein 3 OS=Homo sapiens OX=9606 GN=POLDIP3 PE=1 SV=2 4.65 3076.2 - 800480 - - - 0.9312 - 4.016 0.66 - 344.2 1 2 2 0.0026 26 0 0 0 1.99E+08 1.12E+08 - - - 9.0962 0.9997 221125_WJC_METTL3_EV_vs_WT_F06.19307.19307.2 0.000224 Jun-38 R.VNSASSSNPPAEVDPDTILK.A "sp|Q9BY77|PDIP3_HUMAN,tr|F6VRR5|F6VRR5_HUMAN" 2 2040.0011 1.82 87205 19307 2 2040.002675 1021.0078 Polymerase delta-interacting protein 3 OS=Homo sapiens OX=9606 GN=POLDIP3 PE=1 SV=2 4.03 3077 - 118700 - - - 0.7578 - 1.275 0.544 - 60.4 1 2 0 0.0015 20 0 0 0 2.16E+08 1.19E+08 - - - 3.6558 1 221125_WJC_METTL3_EV_vs_WT_F06.19312.19312.2 2.26E-16 25/40 R.GQTGGDVNVEMDAAPGVDLSR.L "sp|P08779|K1C16_HUMAN,tr|K7ENW6|K7ENW6_HUMAN" 2 2086.9589 614.47 87209 19312 2 2086.962985 1044.4867 "Keratin, type I cytoskeletal 16 OS=Homo sapiens OX=9606 GN=KRT16 PE=1 SV=4" 3.84 3077.5 - 1.15E+06 - - - 1.9349 - 4.324 0.663 - 1246.7 1 2 0 0.004 21 0 0 0 2.27E+08 3.69E+05 - - - 7.5364 0.9991 221125_WJC_METTL3_EV_vs_WT_F06.19313.19313.4 0.0107 17/138 K.GVTIPYR[166.11]PK[136.11]PSSSPVIFAGGQLTK[136.11].L "tr|F8VZX2|F8VZX2_HUMAN,tr|H3BRU6|H3BRU6_HUMAN" 2 2525.4216 1.13 87210 19313 4 2525.423544 632.3627 Poly(rC)-binding protein 2 OS=Homo sapiens OX=9606 GN=PCBP2 PE=1 SV=1 10.29 3077.7 - 1.01E+06 - - - 0.7638 - 2.353 0.297 - 119.4 1 2 0 0.0019 24 0 0 0 2.22E+07 1.96E+07 - - - 2.0852 0.9995 221125_WJC_METTL3_EV_vs_WT_F06.19314.19314.4 0.019 14/78 K.K[136.11]K[136.11]PLDGEYFTLQIR[166.11].G "sp|P04637|P53_HUMAN,tr|A0A087X1Q1|A0A087X1Q1_HUMAN,tr|A0A0U1RQC9|A0A0U1RQC9_HUMAN" 3 1732.9722 1.16 87211 19314 4 1732.972655 434.2503 Cellular tumor antigen p53 OS=Homo sapiens OX=9606 GN=TP53 PE=1 SV=4 8.5 3077.8 - 919248 - - - 0.2476 - 2.282 0.321 - 134.6 1 2 0 0.0004 14 0 0 0 1.53E+07 1.31E+07 - - - 2.3201 1 221125_WJC_METTL3_EV_vs_WT_F06.19316.19316.3 1.04E-12 20/100 R.TLVNK[136.11]EEPPK[136.11]ELPAAEPVLSPLEGTK[136.11].M "sp|Q9BY77|PDIP3_HUMAN,tr|F6VRR5|F6VRR5_HUMAN" 2 2809.5539 1.78 87213 19316 3 2809.554344 937.5253 Polymerase delta-interacting protein 3 OS=Homo sapiens OX=9606 GN=POLDIP3 PE=1 SV=2 4.65 3078.1 - 364587 - - - 0.1484 - 3.891 0.653 - 297.9 1 2 2 0.0004 26 0 0 0 1.99E+08 1.12E+08 - - - 8.946 0.9999 221125_WJC_METTL3_EV_vs_WT_F06.19320.19320.4 5.35E-05 19/114 R.VANYC[160.03]STHLLEHITTNEDFR.A "sp|O75688|PPM1B_HUMAN,tr|B8ZZF0|B8ZZF0_HUMAN,tr|A0A3B3IS24|A0A3B3IS24_HUMAN,tr|C9JIR6|C9JIR6_HUMAN" 4 2419.1227 3.17 87215 19320 4 2419.126199 605.7879 Protein phosphatase 1B OS=Homo sapiens OX=9606 GN=PPM1B PE=1 SV=1 5.27 3078.6 - 1.94E+06 - - - 1.4633 - 3.355 0.441 - 199.4 1 2 0 0.0035 20 0 0 0 5.46E+08 1.72E+08 - - - 3.4682 0.9969 221125_WJC_METTL3_EV_vs_WT_F06.19324.19324.3 9.81E-06 Dec-60 R.ELVFK[136.11]EDGQEYAQVIK[136.11].M "sp|O14602|IF1AY_HUMAN,sp|P47813|IF1AX_HUMAN,tr|A6NJH9|A6NJH9_HUMAN" 3 1910.996 0.54 87219 19324 3 1911.004966 638.006 "Eukaryotic translation initiation factor 1A, Y-chromosomal OS=Homo sapiens OX=9606 GN=EIF1AY PE=1 SV=4" 4.41 3079.1 - 743727 - - - 4.6688 - 2.419 0.453 - 158.4 1 2 1 0.0089 16 0 0 0 6.95E+06 1.28E+07 - - - 5.8546 0.9972 221125_WJC_METTL3_EV_vs_WT_F06.19325.19325.3 0.000113 24/116 K.IGNPVPYNEGLGQPQVAPPAPAASPAASSR.P "sp|P27694|RFA1_HUMAN,tr|I3L2M5|I3L2M5_HUMAN" 2 2912.4781 1.76 87220 19325 3 2912.484104 971.8333 Replication protein A 70 kDa DNA-binding subunit OS=Homo sapiens OX=9606 GN=RPA1 PE=1 SV=2 6 3079.2 - 525263 - - - 2.0718 - 3.464 0.569 - 282.5 1 1 0 0.006 30 0 0 0 4.99E+07 2.83E+07 - - - 7.7405 0.9999 221125_WJC_METTL3_EV_vs_WT_F06.19329.19329.3 2.07E-06 Dec-92 K.GVTIPYRPKPSSSPVIFAGGQLTK.L "tr|F8VZX2|F8VZX2_HUMAN,tr|H3BRU6|H3BRU6_HUMAN" 2 2499.3849 2.19 87224 19329 3 2499.393296 834.1356 Poly(rC)-binding protein 2 OS=Homo sapiens OX=9606 GN=PCBP2 PE=1 SV=1 10.29 3079.7 - 312404 - - - 3.3412 - 2.803 0.599 - 91 1 2 0 0.0084 24 0 0 0 3.54E+06 1.62E+06 - - - 7.6098 0.9728 221125_WJC_METTL3_EV_vs_WT_F06.19330.19330.3 0.024 Aug-44 K.SPYQEFTDHLVK.T "sp|P15880|RS2_HUMAN,tr|E9PQD7|E9PQD7_HUMAN,tr|H0YEN5|H0YEN5_HUMAN" 3 1462.7092 0.9 87225 19330 3 1462.711417 488.577 40S ribosomal protein S2 OS=Homo sapiens OX=9606 GN=RPS2 PE=1 SV=2 5.3 3079.9 - 292440 - - - 1.4849 - 1.519 0.154 - 60.3 1 2 0 0.0022 12 0 0 0 7.72E+06 8.53E+06 - - - 1.4151 0.9998 221125_WJC_METTL3_EV_vs_WT_F06.19332.19332.3 0.00378 Sep-44 K.SPYQEFTDHLVK[136.11].T "sp|P15880|RS2_HUMAN,tr|E9PQD7|E9PQD7_HUMAN,tr|H0YEN5|H0YEN5_HUMAN" 3 1470.7234 0.91 87227 19332 3 1470.72478 491.2484 40S ribosomal protein S2 OS=Homo sapiens OX=9606 GN=RPS2 PE=1 SV=2 5.3 3080.1 - 201997 - - - 0.9077 - 1.701 0.401 - 61.7 1 2 0 0.0013 12 0 0 0 7.72E+06 8.44E+06 - - - 4.4828 1 221125_WJC_METTL3_EV_vs_WT_F06.19336.19336.3 1.64E-13 23/80 R.GQTGGDVNVEMDAAPGVDLSR.L "sp|P08779|K1C16_HUMAN,tr|K7ENW6|K7ENW6_HUMAN" 2 2086.9589 345.83 87229 19336 3 2086.961431 696.6603 "Keratin, type I cytoskeletal 16 OS=Homo sapiens OX=9606 GN=KRT16 PE=1 SV=4" 3.84 3080.6 - 1.30E+07 - - - 1.1902 - 3.837 0.723 - 386.3 1 2 0 0.0025 21 0 0 0 2.71E+08 7.84E+05 - - - 9.8239 1 221125_WJC_METTL3_EV_vs_WT_F06.19337.19337.3 7.32E-15 28/76 R.VANYC[160.03]STHLLEHITTNEDFR.A "sp|O75688|PPM1B_HUMAN,tr|B8ZZF0|B8ZZF0_HUMAN,tr|A0A3B3IS24|A0A3B3IS24_HUMAN,tr|C9JIR6|C9JIR6_HUMAN" 4 2419.1227 3.27 87230 19337 3 2419.12691 807.3815 Protein phosphatase 1B OS=Homo sapiens OX=9606 GN=PPM1B PE=1 SV=1 5.27 3080.7 - 1.82E+06 - - - 1.7572 - 5.224 0.721 - 903.1 1 2 0 0.0043 20 0 0 0 2.36E+08 7.22E+07 - - - 10.5881 0.9995 221125_WJC_METTL3_EV_vs_WT_F06.19342.19342.3 1.26E-06 19/92 K.LYAVHQEGNK[136.11]NVGLDIEAEVPAVK[136.11].D "sp|P50990|TCPQ_HUMAN,tr|H7C2U0|H7C2U0_HUMAN" 2 2608.3832 0.24 87235 19342 3 2608.393979 870.4683 T-complex protein 1 subunit theta OS=Homo sapiens OX=9606 GN=CCT8 PE=1 SV=4 4.83 3081.4 - 1.04E+06 - - - 4.1451 - 3.329 0.604 - 271.8 1 2 1 0.0108 24 0 0 0 1.82E+06 7.70E+06 - - - 8.0643 0.995 221125_WJC_METTL3_EV_vs_WT_F06.19343.19343.4 0.000614 11/186 R.LQAALDDEEAGGRPAMEPGNGSLDLGGDSAGR.S "sp|Q00839|HNRPU_HUMAN,tr|A0A1W2PPS1|A0A1W2PPS1_HUMAN,tr|A0A1X7SBS1|A0A1X7SBS1_HUMAN" 3 3125.432 28.67 87236 19343 4 3126.436504 782.3653 Heterogeneous nuclear ribonucleoprotein U OS=Homo sapiens OX=9606 GN=HNRNPU PE=1 SV=6 3.9 3081.5 - 496111 - - - 321.402 - 2.298 0.409 - 54.6 1 2 0 1.0045 32 0 0 0 1.74E+07 6.06E+05 - - - 2.7589 1 221125_WJC_METTL3_EV_vs_WT_F06.19345.19345.3 1.01E-08 22/76 R.R[166.11]VQIEAAQC[160.03]PDVVVAQIDPK[136.11].K "sp|O14893|GEMI2_HUMAN,tr|A0A3B3IU42|A0A3B3IU42_HUMAN,tr|G5EA29|G5EA29_HUMAN,tr|H0YEL0|H0YEL0_HUMAN" 4 2253.1906 13.56 87238 19345 3 2253.194678 752.0708 Gem-associated protein 2 OS=Homo sapiens OX=9606 GN=GEMIN2 PE=1 SV=1 4.56 3081.8 - 371421 - - - 1.8001 - 3.942 0.587 - 681.9 1 2 0 0.0041 20 0 0 0 7.71E+07 5.69E+06 - - - 8.4111 0.9993 221125_WJC_METTL3_EV_vs_WT_F06.19346.19346.3 0.000323 Nov-44 R.YLYTLVITDKEK.A "sp|P63173|RL38_HUMAN,tr|J3KT73|J3KT73_HUMAN,tr|J3QL01|J3QL01_HUMAN" 3 1484.8126 1.17 87239 19346 3 1484.81364 495.9448 60S ribosomal protein L38 OS=Homo sapiens OX=9606 GN=RPL38 PE=1 SV=2 6.07 3081.9 - 234969 - - - 0.6688 - 1.738 0.421 - 91.2 1 2 1 0.001 12 0 0 0 3.28E+07 2.80E+07 - - - 4.7656 1 221125_WJC_METTL3_EV_vs_WT_F06.19352.19352.4 6.19E-13 24/114 R.VANYC[160.03]STHLLEHITTNEDFR[166.11].A "sp|O75688|PPM1B_HUMAN,tr|B8ZZF0|B8ZZF0_HUMAN,tr|A0A3B3IS24|A0A3B3IS24_HUMAN,tr|C9JIR6|C9JIR6_HUMAN" 4 2429.1309 3.16 87243 19352 4 2429.134798 608.29 Protein phosphatase 1B OS=Homo sapiens OX=9606 GN=PPM1B PE=1 SV=1 5.27 3082.6 - 6.37E+06 - - - 1.5928 - 4.359 0.604 - 305.3 1 2 0 0.0039 20 0 0 0 5.46E+08 1.73E+08 - - - 4.9743 0.9986 221125_WJC_METTL3_EV_vs_WT_F06.19354.19354.3 7.61E-06 27/116 K.IGNPVPYNEGLGQPQVAPPAPAASPAASSR[166.11].P "sp|P27694|RFA1_HUMAN,tr|I3L2M5|I3L2M5_HUMAN" 2 2922.4863 1.76 87245 19354 3 2922.488505 975.1694 Replication protein A 70 kDa DNA-binding subunit OS=Homo sapiens OX=9606 GN=RPA1 PE=1 SV=2 6 3082.8 - 1.57E+06 - - - 0.7408 - 3.453 0.566 - 401.7 1 1 0 0.0022 30 0 0 0 4.99E+07 2.83E+07 - - - 7.7008 0.9724 221125_WJC_METTL3_EV_vs_WT_F06.19356.19356.3 1.40E-08 16/84 K.VPEIEVTVEGPNNNNPQTSAVR.T "sp|P78347|GTF2I_HUMAN,tr|A0A494C1K3|A0A494C1K3_HUMAN" 2 2363.1717 -1 87247 19356 3 2364.159909 788.7312 General transcription factor II-I OS=Homo sapiens OX=9606 GN=GTF2I PE=1 SV=2 4.25 3083 - 1.21E+06 - - - 418.1634 - 3.259 0.521 - 222.8 1 2 0 0.9882 22 0 0 0 0.00E+00 0.00E+00 - - - 6.8759 0.9663 221125_WJC_METTL3_EV_vs_WT_F06.19358.19358.3 3.80E-07 17/84 K.VPEIEVTVEGPNNNNPQTSAVR[166.11].T "sp|P78347|GTF2I_HUMAN,tr|A0A494C1K3|A0A494C1K3_HUMAN" 2 2373.18 -1 87249 19358 3 2374.165719 792.0673 General transcription factor II-I OS=Homo sapiens OX=9606 GN=GTF2I PE=1 SV=2 4.25 3083.2 - 589443 - - - 415.3634 - 3.463 0.568 - 280.2 1 2 0 0.9857 22 0 0 0 0.00E+00 0.00E+00 - - - 7.5445 1 221125_WJC_METTL3_EV_vs_WT_F06.19359.19359.2 2.48E-09 14/34 K.PSTASAVPELATDPELEK[136.11].K "sp|Q86U44|MTA70_HUMAN,tr|B4E349|B4E349_HUMAN,tr|F5H6D8|F5H6D8_HUMAN,tr|H0YFV6|H0YFV6_HUMAN,tr|B4DTN4|B4DTN4_HUMAN" 5 1861.94 0.001 87250 19359 2 1861.943438 931.9773 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 4 3083.3 - 268073 - - - 1.8255 - 2.755 0.605 - 351.7 1 1 0 0.0034 18 0 0 0 0.00E+00 4.88E+07 - - - 6 0.9999 221125_WJC_METTL3_EV_vs_WT_F06.19363.19363.3 3.06E-10 18/100 K.NGFSSVQATQLQTTQSVEGATGSAVK.S "sp|Q14157|UBP2L_HUMAN,tr|F8W726|F8W726_HUMAN" 2 2595.2776 1.79 87252 19363 3 2595.286263 866.0998 Ubiquitin-associated protein 2-like OS=Homo sapiens OX=9606 GN=UBAP2L PE=1 SV=2 6 3083.8 - 1.75E+06 - - - 3.323 - 3.395 0.582 - 322.1 1 2 0 0.0086 26 0 0 0 1.41E+07 7.87E+06 - - - 7.8384 1 221125_WJC_METTL3_EV_vs_WT_F06.19365.19365.3 3.71E-11 23/68 R.SELHIENLNMEADPGQYR.C "sp|P35613|BASI_HUMAN,tr|A0A7P0T8A7|A0A7P0T8A7_HUMAN,tr|A0A087WUV8|A0A087WUV8_HUMAN,tr|A0A7P0TA85|A0A7P0TA85_HUMAN,tr|A0A7P0TB04|A0A7P0TB04_HUMAN" 5 2114.9691 1.48 87254 19365 3 2114.974987 705.997 Basigin OS=Homo sapiens OX=9606 GN=BSG PE=1 SV=2 4.4 3083.9 - 1.65E+06 - - - 2.775 - 3.895 0.612 - 427 1 2 0 0.0059 18 0 0 0 4.02E+07 2.73E+07 - - - 8.7473 1 221125_WJC_METTL3_EV_vs_WT_F06.19369.19369.2 9.62E-13 18/38 R.FSSC[160.03]GGGGGSFGAGGGFGSR.S sp|P04264|K2C1_HUMAN 1 1764.7274 999 87258 19369 2 1764.731245 883.371 "Keratin, type II cytoskeletal 1 OS=Homo sapiens OX=9606 GN=KRT1 PE=1 SV=6" 8.25 3084.5 - 456054 - - - 2.1612 - 3.521 0.763 - 691.1 1 2 0 0.0038 20 0 0 0 6.78E+06 0.00E+00 - - - 7.77 1 221125_WJC_METTL3_EV_vs_WT_F06.19373.19373.3 7.75E-09 17/68 R.HDIAFVEFENDGQAGAAR.D sp|P08579|RU2B_HUMAN 1 1945.8919 1.38 87261 19373 3 1945.895239 649.6379 U2 small nuclear ribonucleoprotein B'' OS=Homo sapiens OX=9606 GN=SNRPB2 PE=1 SV=1 4.31 3084.9 - 3.32E+06 - - - 1.7396 - 3.378 0.601 - 421.6 1 2 0 0.0034 18 0 0 0 5.93E+07 4.29E+07 - - - 8.2708 1 221125_WJC_METTL3_EV_vs_WT_F06.19375.19375.3 9.03E-14 26/76 R.VANYC[160.03]STHLLEHITTNEDFR[166.11].A "sp|O75688|PPM1B_HUMAN,tr|B8ZZF0|B8ZZF0_HUMAN,tr|A0A3B3IS24|A0A3B3IS24_HUMAN,tr|C9JIR6|C9JIR6_HUMAN" 4 2429.1309 3.27 87262 19375 3 2429.131302 810.7176 Protein phosphatase 1B OS=Homo sapiens OX=9606 GN=PPM1B PE=1 SV=1 5.27 3085.1 - 5.67E+06 - - - 0.1536 - 4.879 0.694 - 628.1 1 2 0 0.0004 20 0 0 0 2.36E+08 7.22E+07 - - - 10.1224 0.9996 221125_WJC_METTL3_EV_vs_WT_F06.19378.19378.3 1.20E-07 17/56 R.STSHK[136.11]PDEIYGMIER[166.11].L sp|Q86U44|MTA70_HUMAN 1 1779.8581 0.19 87265 19378 3 1779.863703 594.2933 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 5.42 3085.5 - 621799 - - - 3.1738 - 2.83 0.368 - 351.5 1 2 0 0.0056 15 0 0 0 1.67E+06 8.96E+06 - - - 5.3557 1 221125_WJC_METTL3_EV_vs_WT_F06.19380.19380.4 1.56E-07 17/78 K.LHNMIVDLDNVVKK.V "sp|Q16891|MIC60_HUMAN,tr|B9A067|B9A067_HUMAN,tr|C9J406|C9J406_HUMAN,tr|H7C463|H7C463_HUMAN" 4 1636.8971 1.16 87267 19380 4 1636.893655 410.2315 MICOS complex subunit MIC60 OS=Homo sapiens OX=9606 GN=IMMT PE=1 SV=1 6.75 3085.8 - 329186 - - - -2.0814 - 3.25 0.546 - 337.3 1 2 0 -0.0034 14 0 0 0 1.21E+07 1.05E+07 - - - 4.4064 0.9991 221125_WJC_METTL3_EV_vs_WT_F06.19384.19384.4 2.44E-05 15/138 K.LYAVHQEGNKNVGLDIEAEVPAVK.D "sp|P50990|TCPQ_HUMAN,tr|H7C2U0|H7C2U0_HUMAN" 2 2592.3548 0.37 87269 19384 4 2592.362718 649.096 T-complex protein 1 subunit theta OS=Homo sapiens OX=9606 GN=CCT8 PE=1 SV=4 4.83 3086.3 - 2.45E+06 - - - 3.0671 - 2.706 0.447 - 75.4 1 2 1 0.008 24 0 0 0 4.92E+07 1.35E+08 - - - 3.434 0.9999 221125_WJC_METTL3_EV_vs_WT_F06.19385.19385.4 4.03E-08 18/108 R.ESVPLDDQEKLPFTVVHER.E sp|Q96S52|PIGS_HUMAN 1 2237.1328 1.73 87270 19385 4 2237.135156 560.2905 GPI transamidase component PIG-S OS=Homo sapiens OX=9606 GN=PIGS PE=1 SV=3 4.5 3086.4 - 1.21E+06 - - - 1.0478 - 2.985 0.528 - 230.6 1 2 1 0.0023 19 0 0 0 2.47E+07 1.43E+07 - - - 4.191 0.8751 221125_WJC_METTL3_EV_vs_WT_F06.19386.19386.3 0.00164 17/124 R.LQAALDDEEAGGR[166.11]PAMEPGNGSLDLGGDSAGR[166.11].S "sp|Q00839|HNRPU_HUMAN,tr|A0A1W2PPS1|A0A1W2PPS1_HUMAN,tr|A0A1X7SBS1|A0A1X7SBS1_HUMAN" 3 3145.4485 -1 87271 19386 3 3146.430682 1049.4901 Heterogeneous nuclear ribonucleoprotein U OS=Homo sapiens OX=9606 GN=HNRNPU PE=1 SV=6 3.9 3086.5 - 2.65E+06 - - - 312.2474 - 2.467 0.442 - 220 1 2 0 0.9822 32 0 0 0 0.00E+00 0.00E+00 - - - 5.2733 0.9999 221125_WJC_METTL3_EV_vs_WT_F06.19387.19387.3 1.05E-06 24/72 K.LAAAILGGVDQIHIKPGAK.V "sp|P22087|FBRL_HUMAN,tr|M0R299|M0R299_HUMAN,tr|M0R0P1|M0R0P1_HUMAN,tr|M0R1H0|M0R1H0_HUMAN,tr|M0QXL5|M0QXL5_HUMAN,tr|M0R2Q4|M0R2Q4_HUMAN,tr|M0R2B0|M0R2B0_HUMAN,tr|M0R2U2|M0R2U2_HUMAN" 8 1871.0993 0.85 87272 19387 3 1871.105708 624.707 rRNA 2'-O-methyltransferase fibrillarin OS=Homo sapiens OX=9606 GN=FBL PE=1 SV=2 8.6 3086.6 - 875898 - - - 3.4418 - 3.932 0.549 - 777.9 1 2 0 0.0064 19 0 0 0 1.32E+07 1.56E+07 - - - 8.0228 1 221125_WJC_METTL3_EV_vs_WT_F06.19388.19388.3 1.42E-09 18/52 K.LHNMIVDLDNVVK[136.11]K[136.11].V "sp|Q16891|MIC60_HUMAN,tr|B9A067|B9A067_HUMAN,tr|C9J406|C9J406_HUMAN,tr|H7C463|H7C463_HUMAN" 4 1652.9255 1.19 87273 19388 3 1652.924517 551.9824 MICOS complex subunit MIC60 OS=Homo sapiens OX=9606 GN=IMMT PE=1 SV=1 6.75 3086.8 - 761982 - - - -0.5717 - 3.023 0.603 - 628.7 1 2 0 -0.0009 14 0 0 0 1.51E+07 1.27E+07 - - - 8.2025 1 221125_WJC_METTL3_EV_vs_WT_F06.19389.19389.3 0.0019 16/48 K.KNAAIAVLEELKK.L "sp|O95793|STAU1_HUMAN,tr|Q5JW30|Q5JW30_HUMAN,tr|Q5JW28|Q5JW28_HUMAN" 3 1425.8555 2.15 87274 19389 3 1425.855102 476.2924 Double-stranded RNA-binding protein Staufen homolog 1 OS=Homo sapiens OX=9606 GN=STAU1 PE=1 SV=2 8.5 3086.9 - 725684 - - - -0.2897 - 3.207 0.485 - 372.9 1 2 0 -0.0004 13 0 0 0 2.42E+07 1.13E+07 - - - 7.1067 1 221125_WJC_METTL3_EV_vs_WT_F06.19390.19390.4 2.73E-08 17/78 K.LHNMIVDLDNVVK[136.11]K[136.11].V "sp|Q16891|MIC60_HUMAN,tr|B9A067|B9A067_HUMAN,tr|C9J406|C9J406_HUMAN,tr|H7C463|H7C463_HUMAN" 4 1652.9255 1.16 87275 19390 4 1652.925912 414.2386 MICOS complex subunit MIC60 OS=Homo sapiens OX=9606 GN=IMMT PE=1 SV=1 6.75 3087 - 563121 - - - 0.2722 - 2.773 0.595 - 317.9 1 2 0 0.0004 14 0 0 0 1.22E+07 1.05E+07 - - - 4.776 1 221125_WJC_METTL3_EV_vs_WT_F06.19396.19396.4 1.34E-07 15/108 R.GLLQDDAHPTLVTYADHSK[136.11].L "sp|Q86U44|MTA70_HUMAN,tr|F5H6D8|F5H6D8_HUMAN,tr|H0YFV6|H0YFV6_HUMAN,tr|B4DTN4|B4DTN4_HUMAN" 4 2088.0367 0.01 87279 19396 4 2088.036032 523.0165 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 5.13 3087.7 - 2.82E+06 - - - -0.3357 - 3.024 0.604 - 237.5 1 2 0 -0.0007 19 0 0 0 3.19E+05 3.96E+07 - - - 4.8574 1 221125_WJC_METTL3_EV_vs_WT_F06.19402.19402.2 2.54E-10 14/32 R.DNSEVQFNSAVPTNLSR[166.11].G sp|Q96SZ6|CK5P1_HUMAN 1 1886.8998 1.01 87285 19402 2 1887.892031 944.4572 Mitochondrial tRNA methylthiotransferase CDK5RAP1 OS=Homo sapiens OX=9606 GN=CDK5RAP1 PE=1 SV=2 4.37 3088.4 - 312932 - - - 525.8583 - 2.695 0.69 - 341.9 1 2 0 0.9922 17 0 0 0 1.10E+07 1.09E+07 - - - 6.2632 0.9983 221125_WJC_METTL3_EV_vs_WT_F06.19405.19405.4 0.0136 14/114 K.ALVLNGKPGHLQFYSLQSDK.Q sp|Q8IWA0|WDR75_HUMAN 1 2214.1797 0.77 87286 19405 4 2214.181715 554.5522 WD repeat-containing protein 75 OS=Homo sapiens OX=9606 GN=WDR75 PE=1 SV=1 8.55 3088.8 - 1.31E+06 - - - 0.9087 - 2.075 0.271 - 78.5 1 2 0 0.002 20 0 0 0 3.03E+07 3.91E+07 - - - 1.8283 1 221125_WJC_METTL3_EV_vs_WT_F06.19406.19406.3 2.46E-08 21/52 K.LHNMIVDLDNVVKK.V "sp|Q16891|MIC60_HUMAN,tr|B9A067|B9A067_HUMAN,tr|C9J406|C9J406_HUMAN,tr|H7C463|H7C463_HUMAN" 4 1636.8971 1.13 87287 19406 3 1636.897424 546.6396 MICOS complex subunit MIC60 OS=Homo sapiens OX=9606 GN=IMMT PE=1 SV=1 6.75 3088.9 - 1.36E+06 - - - 0.2212 - 3.544 0.624 - 998.7 1 2 0 0.0004 14 0 0 0 1.51E+07 1.33E+07 - - - 8.8593 0.9752 221125_WJC_METTL3_EV_vs_WT_F06.19408.19408.3 0.0981 Dec-44 K.QK[136.11]VDSLLENLEK[136.11].L "sp|P0DMR1|HNRC4_HUMAN,sp|P07910|HNRPC_HUMAN,sp|O60812|HNRC1_HUMAN,sp|B2RXH8|HNRC2_HUMAN,sp|B7ZW38|HNRC3_HUMAN,tr|B4DY08|B4DY08_HUMAN,tr|G3V5V7|G3V5V7_HUMAN,tr|B2R5W2|B2R5W2_HUMAN,tr|G3V4C1|G3V4C1_HUMAN,tr|A0A0G2JPF8|A0A0G2JPF8_HUMAN,tr|A0A0G2JNQ3|A0A0G2JNQ3_HUMAN,tr|G3V576|G3V576_HUMAN,tr|G3V2D6|G3V2D6_HUMAN,tr|G3V4W0|G3V4W0_HUMAN,tr|G3V2Q1|G3V2Q1_HUMAN" 15 1430.7952 1.45 87289 19408 3 1430.795528 477.939 Heterogeneous nuclear ribonucleoprotein C-like 4 OS=Homo sapiens OX=9606 GN=HNRNPCL4 PE=3 SV=1 4.68 3089.1 - 1.74E+06 - - - 0.2572 - 1.828 0.176 - 266.8 1 2 1 0.0004 12 0 0 0 1.68E+08 1.16E+08 - - - 2.1742 1 221125_WJC_METTL3_EV_vs_WT_F06.19414.19414.3 5.50E-10 20/88 K.KIDAAQNWLADPNGGPEGEEQIR.G sp|P18206|VINC_HUMAN 1 2507.2041 1.21 87295 19414 3 2507.211079 836.742 Vinculin OS=Homo sapiens OX=9606 GN=VCL PE=1 SV=4 4.18 3089.8 - 544396 - - - 2.7916 - 3.889 0.591 - 490.7 1 2 0 0.007 23 0 0 0 4.91E+06 4.06E+06 - - - 8.3133 1 221125_WJC_METTL3_EV_vs_WT_F06.19419.19419.4 1.00E-08 19/114 K.ALVLNGK[136.11]PGHLQFYSLQSDK[136.11].Q sp|Q8IWA0|WDR75_HUMAN 1 2230.2081 0.77 87298 19419 4 2230.20987 558.5593 WD repeat-containing protein 75 OS=Homo sapiens OX=9606 GN=WDR75 PE=1 SV=1 8.55 3090.4 - 4.11E+06 - - - 0.7923 - 3.513 0.513 - 206.1 1 2 0 0.0018 20 0 0 0 3.03E+07 3.91E+07 - - - 4.1107 0.9999 221125_WJC_METTL3_EV_vs_WT_F06.19421.19421.4 5.54E-07 21/108 R.LKVGLQVVAVKAPGFGDNR.K "sp|P10809|CH60_HUMAN,tr|A0A7I2V2X6|A0A7I2V2X6_HUMAN,tr|A0A7I2YQK6|A0A7I2YQK6_HUMAN,tr|A0A7I2V599|A0A7I2V599_HUMAN,tr|A0A7I2V5M1|A0A7I2V5M1_HUMAN" 5 1967.1316 1.35 87300 19421 4 1967.133302 492.7902 "60 kDa heat shock protein, mitochondrial OS=Homo sapiens OX=9606 GN=HSPD1 PE=1 SV=2" 9.99 3090.7 - 1.56E+06 - - - 0.85 - 3.606 0.612 - 280 1 2 2 0.0017 19 0 0 0 8.28E+07 6.13E+07 - - - 4.9863 1 221125_WJC_METTL3_EV_vs_WT_F06.19423.19423.3 2.16E-15 24/100 R.SPVIGSEVFLPNSNHVASGAGEAEER.V "sp|P29590|PML_HUMAN,tr|H3BVD2|H3BVD2_HUMAN" 2 2652.278 1.03 87302 19423 3 2652.284637 885.0999 Protein PML OS=Homo sapiens OX=9606 GN=PML PE=1 SV=3 4.48 3090.9 - 1.03E+06 - - - 2.5126 - 4.722 0.69 - 491.2 1 2 0 0.0067 26 0 0 0 2.03E+07 1.98E+07 - - - 9.8021 0.9999 221125_WJC_METTL3_EV_vs_WT_F06.19425.19425.3 1.87E-08 18/72 R.C[160.03]VFEMPNENDKLNDMEPSK.A sp|Q9P0L0|VAPA_HUMAN 1 2295.981 0.95 87304 19425 3 2295.983574 766.3343 Vesicle-associated membrane protein-associated protein A OS=Homo sapiens OX=9606 GN=VAPA PE=1 SV=3 4.18 3091.1 - 940315 - - - 1.1189 - 3.315 0.562 - 227.1 1 2 1 0.0026 19 0 0 0 1.22E+07 1.28E+07 - - - 7.7494 0.9977 221125_WJC_METTL3_EV_vs_WT_F06.19426.19426.2 0.000488 22-Nov K.QK[136.11]VDSLLENLEK[136.11].L "sp|P0DMR1|HNRC4_HUMAN,sp|P07910|HNRPC_HUMAN,sp|O60812|HNRC1_HUMAN,sp|B2RXH8|HNRC2_HUMAN,sp|B7ZW38|HNRC3_HUMAN,tr|B4DY08|B4DY08_HUMAN,tr|G3V5V7|G3V5V7_HUMAN,tr|B2R5W2|B2R5W2_HUMAN,tr|G3V4C1|G3V4C1_HUMAN,tr|A0A0G2JPF8|A0A0G2JPF8_HUMAN,tr|A0A0G2JNQ3|A0A0G2JNQ3_HUMAN,tr|G3V576|G3V576_HUMAN,tr|G3V2D6|G3V2D6_HUMAN,tr|G3V4W0|G3V4W0_HUMAN,tr|G3V2Q1|G3V2Q1_HUMAN" 15 1430.7952 1.57 87305 19426 2 1430.796416 716.4049 Heterogeneous nuclear ribonucleoprotein C-like 4 OS=Homo sapiens OX=9606 GN=HNRNPCL4 PE=3 SV=1 4.68 3091.3 - 841869 - - - 0.8778 - 2.281 0.423 - 322.1 1 2 1 0.0013 12 0 0 0 5.18E+07 3.29E+07 - - - 4.3346 1 221125_WJC_METTL3_EV_vs_WT_F06.19434.19434.3 2.17E-07 28/80 R.K[136.11]VETDHIVAAVGLEPNVELAK[136.11].T "sp|O95831|AIFM1_HUMAN,tr|A0A6Q8PFA7|A0A6Q8PFA7_HUMAN,tr|A0A6Q8PHJ9|A0A6Q8PHJ9_HUMAN,tr|A0A6Q8PFS4|A0A6Q8PFS4_HUMAN,tr|E9PMA0|E9PMA0_HUMAN,tr|A0A7I2PK44|A0A7I2PK44_HUMAN,tr|A0A6Q8PG15|A0A6Q8PG15_HUMAN,tr|A0A6Q8PFE1|A0A6Q8PFE1_HUMAN,tr|A0A7I2RLJ8|A0A7I2RLJ8_HUMAN,tr|A0A6Q8PFQ8|A0A6Q8PFQ8_HUMAN,tr|A0A6Q8PHC0|A0A6Q8PHC0_HUMAN,tr|A0A6Q8PFM5|A0A6Q8PFM5_HUMAN" 12 2247.2445 0.93 87311 19434 3 2247.243514 750.0888 "Apoptosis-inducing factor 1, mitochondrial OS=Homo sapiens OX=9606 GN=AIFM1 PE=1 SV=1" 4.83 3092.2 - 3.23E+06 - - - -0.4601 - 5.39 0.605 - 1103.8 1 2 0 -0.001 21 0 0 0 3.55E+07 3.82E+07 - - - 9.3235 1 221125_WJC_METTL3_EV_vs_WT_F06.19435.19435.4 2.49E-09 20/108 R.LK[136.11]VGLQVVAVK[136.11]APGFGDNR[166.11].K "sp|P10809|CH60_HUMAN,tr|A0A7I2V2X6|A0A7I2V2X6_HUMAN,tr|A0A7I2YQK6|A0A7I2YQK6_HUMAN,tr|A0A7I2V599|A0A7I2V599_HUMAN,tr|A0A7I2V5M1|A0A7I2V5M1_HUMAN" 5 1993.1683 1.35 87312 19435 4 1993.169103 499.2994 "60 kDa heat shock protein, mitochondrial OS=Homo sapiens OX=9606 GN=HSPD1 PE=1 SV=2" 9.99 3092.3 - 2.98E+06 - - - 0.4029 - 3.838 0.64 - 277.2 1 2 2 0.0008 19 0 0 0 8.28E+07 6.13E+07 - - - 5.2513 1 221125_WJC_METTL3_EV_vs_WT_F06.19436.19436.3 1.87E-09 18/76 K.ISSPDYKDC[160.03]NSAEAMDDFMK.R "sp|Q16875|F263_HUMAN,tr|A0A1W2PR17|A0A1W2PR17_HUMAN,tr|Q5W015|Q5W015_HUMAN,tr|F2Z2I2|F2Z2I2_HUMAN,tr|Q5VX20|Q5VX20_HUMAN" 5 2322.9443 4.23 87313 19436 3 2322.950502 775.322 "6-phosphofructo-2-kinase\fructose-2,6-bisphosphatase 3 OS=Homo sapiens OX=9606 GN=PFKFB3 PE=1 SV=1" 4.04 3092.4 - 1.72E+06 - - - 2.6763 - 3.78 0.708 - 535.6 1 2 1 0.0062 20 0 0 0 5.15E+07 1.22E+07 - - - 9.6577 1 221125_WJC_METTL3_EV_vs_WT_F06.19437.19437.3 8.50E-12 25/72 R.LKVGLQVVAVKAPGFGDNR.K "sp|P10809|CH60_HUMAN,tr|A0A7I2V2X6|A0A7I2V2X6_HUMAN,tr|A0A7I2YQK6|A0A7I2YQK6_HUMAN,tr|A0A7I2V599|A0A7I2V599_HUMAN,tr|A0A7I2V5M1|A0A7I2V5M1_HUMAN" 5 1967.1316 1.35 87314 19437 3 1967.132024 656.7178 "60 kDa heat shock protein, mitochondrial OS=Homo sapiens OX=9606 GN=HSPD1 PE=1 SV=2" 9.99 3092.5 - 1.33E+06 - - - 0.2003 - 4.23 0.669 - 647.2 1 2 2 0.0004 19 0 0 0 2.91E+07 2.16E+07 - - - 9.5418 1 221125_WJC_METTL3_EV_vs_WT_F06.19439.19439.3 9.18E-06 18/64 R.HSQQLFPDGSPGDQWVK[136.11].H "sp|Q8IU60|DCP2_HUMAN,tr|B7Z3U5|B7Z3U5_HUMAN" 2 1932.921 2.09 87316 19439 3 1932.927103 645.3143 m7GpppN-mRNA hydrolase OS=Homo sapiens OX=9606 GN=DCP2 PE=1 SV=3 5.21 3092.8 - 877767 - - - 3.1703 - 3.441 0.571 - 413.8 1 2 0 0.0061 17 0 0 0 3.12E+07 1.50E+07 - - - 8.0263 0.9999 221125_WJC_METTL3_EV_vs_WT_F06.19441.19441.3 9.56E-09 13/72 R.C[160.03]VFEMPNENDK[136.11]LNDMEPSK[136.11].A sp|Q9P0L0|VAPA_HUMAN 1 2312.0094 0.97 87318 19441 3 2312.008615 771.6771 Vesicle-associated membrane protein-associated protein A OS=Homo sapiens OX=9606 GN=VAPA PE=1 SV=3 4.18 3093 - 739164 - - - -0.3417 - 2.609 0.589 - 108.3 1 2 1 -0.0008 19 0 0 0 1.22E+07 1.26E+07 - - - 7.4625 1 221125_WJC_METTL3_EV_vs_WT_F06.19442.19442.2 4.11E-10 16/32 R.DNSEVQFNSAVPTNLSR.G sp|Q96SZ6|CK5P1_HUMAN 1 1876.8915 1.01 87319 19442 2 1876.891775 939.453 Mitochondrial tRNA methylthiotransferase CDK5RAP1 OS=Homo sapiens OX=9606 GN=CDK5RAP1 PE=1 SV=2 4.37 3093.1 - 563645 - - - 0.1364 - 3.224 0.669 - 489.4 1 2 0 0.0003 17 0 0 0 1.10E+07 1.09E+07 - - - 6.8602 1 221125_WJC_METTL3_EV_vs_WT_F06.19446.19446.3 9.60E-11 28/80 R.KVETDHIVAAVGLEPNVELAK.T "sp|O95831|AIFM1_HUMAN,tr|A0A6Q8PFA7|A0A6Q8PFA7_HUMAN,tr|A0A6Q8PHJ9|A0A6Q8PHJ9_HUMAN,tr|A0A6Q8PFS4|A0A6Q8PFS4_HUMAN,tr|E9PMA0|E9PMA0_HUMAN,tr|A0A7I2PK44|A0A7I2PK44_HUMAN,tr|A0A6Q8PG15|A0A6Q8PG15_HUMAN,tr|A0A6Q8PFE1|A0A6Q8PFE1_HUMAN,tr|A0A7I2RLJ8|A0A7I2RLJ8_HUMAN,tr|A0A6Q8PFQ8|A0A6Q8PFQ8_HUMAN,tr|A0A6Q8PHC0|A0A6Q8PHC0_HUMAN,tr|A0A6Q8PFM5|A0A6Q8PFM5_HUMAN" 12 2231.2161 0.92 87321 19446 3 2231.215773 744.746 "Apoptosis-inducing factor 1, mitochondrial OS=Homo sapiens OX=9606 GN=AIFM1 PE=1 SV=1" 4.83 3093.6 - 3.22E+06 - - - -0.1681 - 4.639 0.422 - 932.8 1 2 0 -0.0004 21 0 0 0 3.51E+07 3.82E+07 - - - 6.9237 1 221125_WJC_METTL3_EV_vs_WT_F06.19447.19447.3 1.81E-08 17/68 K.YVHYEIDAC[160.03]MDSEAPGSK[136.11].D "sp|Q86U44|MTA70_HUMAN,tr|H0YFV6|H0YFV6_HUMAN" 2 2078.8805 0.01 87322 19447 3 2078.880924 693.9674 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 4.31 3093.7 - 2.79E+06 - - - 0.2078 - 3.553 0.64 - 317 1 2 0 0.0004 18 0 0 0 8.65E+05 1.46E+08 - - - 8.8322 1 221125_WJC_METTL3_EV_vs_WT_F06.19448.19448.3 4.83E-12 18/72 R.LK[136.11]VGLQVVAVK[136.11]APGFGDNR[166.11].K "sp|P10809|CH60_HUMAN,tr|A0A7I2V2X6|A0A7I2V2X6_HUMAN,tr|A0A7I2YQK6|A0A7I2YQK6_HUMAN,tr|A0A7I2V599|A0A7I2V599_HUMAN,tr|A0A7I2V5M1|A0A7I2V5M1_HUMAN" 5 1993.1683 1.35 87323 19448 3 1993.165816 665.3967 "60 kDa heat shock protein, mitochondrial OS=Homo sapiens OX=9606 GN=HSPD1 PE=1 SV=2" 9.99 3093.8 - 1.21E+06 - - - -1.2463 - 3.523 0.605 - 307.7 1 2 2 -0.0025 19 0 0 0 2.91E+07 2.16E+07 - - - 8.3783 0.9999 221125_WJC_METTL3_EV_vs_WT_F06.19449.19449.3 5.81E-06 16/76 K.ALVLNGKPGHLQFYSLQSDK.Q sp|Q8IWA0|WDR75_HUMAN 1 2214.1797 0.32 87324 19449 3 2214.186691 739.0672 WD repeat-containing protein 75 OS=Homo sapiens OX=9606 GN=WDR75 PE=1 SV=1 8.55 3093.9 - 407724 - - - 3.156 - 3.492 0.562 - 242.9 1 2 0 0.007 20 0 0 0 8.11E+06 2.51E+07 - - - 7.8375 1 221125_WJC_METTL3_EV_vs_WT_F06.19453.19453.3 1.66E-10 21/76 K.ISSPDYK[136.11]DC[160.03]NSAEAMDDFMK[136.11].R "sp|Q16875|F263_HUMAN,tr|A0A1W2PR17|A0A1W2PR17_HUMAN,tr|Q5W015|Q5W015_HUMAN,tr|F2Z2I2|F2Z2I2_HUMAN,tr|Q5VX20|Q5VX20_HUMAN" 5 2338.9727 4.23 87326 19453 3 2338.972535 780.6648 "6-phosphofructo-2-kinase\fructose-2,6-bisphosphatase 3 OS=Homo sapiens OX=9606 GN=PFKFB3 PE=1 SV=1" 4.04 3094.4 - 926082 - - - -0.0641 - 3.813 0.664 - 700 1 2 1 -0.0001 20 0 0 0 5.15E+07 1.22E+07 - - - 9.1899 0.9214 221125_WJC_METTL3_EV_vs_WT_F06.19455.19455.4 0.00112 Dec-96 L.SWLDANTLAEK[136.11]DEFEHK[136.11].R "sp|P0DMV8|HS71A_HUMAN,sp|P0DMV9|HS71B_HUMAN,tr|V9GZ37|V9GZ37_HUMAN,tr|A0A0G2JIW1|A0A0G2JIW1_HUMAN" 4 2047.9822 0.08 87328 19455 4 2047.983697 513.0028 Heat shock 70 kDa protein 1A OS=Homo sapiens OX=9606 GN=HSPA1A PE=1 SV=1 4.5 3094.6 - 1.41E+06 - - - 0.7383 - 2.304 0.385 - 65 1 1 1 0.0015 17 0 0 0 1.26E+06 1.54E+07 - - - 2.8664 0.9513 221125_WJC_METTL3_EV_vs_WT_F06.19456.19456.3 1.44E-06 20/68 K.PSTASAVPELATDPELEK[136.11].K "sp|Q86U44|MTA70_HUMAN,tr|B4E349|B4E349_HUMAN,tr|F5H6D8|F5H6D8_HUMAN,tr|H0YFV6|H0YFV6_HUMAN,tr|B4DTN4|B4DTN4_HUMAN" 5 1861.94 0 87329 19456 3 1862.944629 621.654 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 4 3094.7 - 1.14E+06 - - - 539.5394 - 3.527 0.526 - 496 1 1 0 1.0046 18 0 0 0 1.29E+05 2.60E+07 - - - 7.2648 1 221125_WJC_METTL3_EV_vs_WT_F06.19461.19461.3 3.98E-10 17/60 R.QSEVPDSVYQHLVQDR.H "sp|Q9P2R6|RERE_HUMAN,tr|A0A590UK57|A0A590UK57_HUMAN,tr|H0Y975|H0Y975_HUMAN,tr|H7BYW9|H7BYW9_HUMAN,tr|A0A590UJ84|A0A590UJ84_HUMAN" 5 1898.9123 9.87 87332 19461 3 1898.912626 633.978 Arginine-glutamic acid dipeptide repeats protein OS=Homo sapiens OX=9606 GN=RERE PE=1 SV=2 4.54 3095.5 - 1.35E+06 - - - 0.1954 - 3.744 0.597 - 534.6 1 2 0 0.0004 16 0 0 0 2.65E+07 2.68E+06 - - - 8.5832 0.968 221125_WJC_METTL3_EV_vs_WT_F06.19475.19475.3 0.168 Sep-72 R.GLLQDDAHPTLVTYADHSK[136.11].L "sp|Q86U44|MTA70_HUMAN,tr|F5H6D8|F5H6D8_HUMAN,tr|H0YFV6|H0YFV6_HUMAN,tr|B4DTN4|B4DTN4_HUMAN" 4 2088.0367 0.04 87344 19475 3 2088.045122 697.0195 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 5.13 3097 - 1.03E+06 - - - 4.0176 - 1.865 0.206 - 59.3 1 2 0 0.0084 19 0 0 0 1.41E+06 3.26E+07 - - - 2.3656 1 221125_WJC_METTL3_EV_vs_WT_F06.19477.19477.3 1.63E-08 15/96 K.QLESLWSDSPAPPGPQAGPPSRPPR.Y "sp|Q8WUF5|IASPP_HUMAN,tr|K7EN03|K7EN03_HUMAN" 2 2623.3143 999 87346 19477 3 2623.314795 875.4454 RelA-associated inhibitor OS=Homo sapiens OX=9606 GN=PPP1R13L PE=1 SV=4 6.07 3097.3 - 949069 - - - 0.1891 - 3.055 0.568 - 199.7 1 2 0 0.0005 25 0 0 0 8.05E+06 0.00E+00 - - - 7.4418 1 221125_WJC_METTL3_EV_vs_WT_F06.19482.19482.3 8.42E-15 24/100 R.MAEIGEHVAPSEAANSLEQAQAAAER[166.11].L "sp|P27708|PYR1_HUMAN,tr|F8VPD4|F8VPD4_HUMAN" 2 2689.2641 0.51 87349 19482 3 2689.258978 897.4287 CAD protein OS=Homo sapiens OX=9606 GN=CAD PE=1 SV=3 4.32 3097.9 - 937360 - - - -1.9147 - 5.052 0.71 - 648 1 2 0 -0.0052 26 0 0 0 2.60E+07 5.07E+07 - - - 10.1809 0.9999 221125_WJC_METTL3_EV_vs_WT_F06.19484.19484.3 0.000807 15/68 K.TVTNAVVTVPAYFNDSQR[166.11].Q "sp|P11142|HSP7C_HUMAN,tr|E9PQQ4|E9PQQ4_HUMAN,tr|E9PN89|E9PN89_HUMAN,tr|E9PLF4|E9PLF4_HUMAN,tr|E9PI65|E9PI65_HUMAN,tr|E9PK54|E9PK54_HUMAN,tr|E9PQK7|E9PQK7_HUMAN" 7 1990.9988 0.39 87351 19484 3 1991.001299 664.6735 Heat shock cognate 71 kDa protein OS=Homo sapiens OX=9606 GN=HSPA8 PE=1 SV=1 5.5 3098.2 - 1.43E+06 - - - 1.2677 - 2.782 0.424 - 220.8 1 2 0 0.0025 18 0 0 0 8.55E+06 2.21E+07 - - - 5.8143 1 221125_WJC_METTL3_EV_vs_WT_F06.19492.19492.3 5.91E-16 23/76 K.ADEHVIDQGDDGDNFYVIER.G "sp|P13861|KAP2_HUMAN,tr|H7C1L0|H7C1L0_HUMAN" 2 2306.0087 2.05 87357 19492 3 2306.017772 769.6769 cAMP-dependent protein kinase type II-alpha regulatory subunit OS=Homo sapiens OX=9606 GN=PRKAR2A PE=1 SV=2 3.85 3099.1 - 2.84E+06 - - - 3.9193 - 4.251 0.775 - 644.1 1 2 0 0.009 20 0 0 0 4.06E+08 1.98E+08 - - - 10.6888 0.9998 221125_WJC_METTL3_EV_vs_WT_F06.19493.19493.3 1.15E-05 Nov-72 R.LQPYNGVALRPWDGNSDDR.V "sp|Q3ZCQ8|TIM50_HUMAN,tr|M0R1Y4|M0R1Y4_HUMAN,tr|M0R0C3|M0R0C3_HUMAN,tr|M0R2F8|M0R2F8_HUMAN,tr|M0R003|M0R003_HUMAN" 5 2172.0348 0.41 87358 19493 3 2172.029238 725.0189 Mitochondrial import inner membrane translocase subunit TIM50 OS=Homo sapiens OX=9606 GN=TIMM50 PE=1 SV=2 4.43 3099.2 - 1.60E+06 - - - -2.5741 - 2.142 0.458 - 121.1 1 2 0 -0.0056 19 0 0 0 3.68E+07 9.01E+07 - - - 5.5161 0.9946 221125_WJC_METTL3_EV_vs_WT_F06.19495.19495.3 0.000854 15/108 K.GDLGPASPSQELGSQPVPGGDGAPALGK.S "sp|Q4KMQ1|TPRN_HUMAN,tr|H3BLU1|H3BLU1_HUMAN" 2 2558.2613 32.13 87360 19495 3 2558.247255 853.761 Taperin OS=Homo sapiens OX=9606 GN=TPRN PE=1 SV=2 4.03 3099.5 - 1.09E+06 - - - -5.4744 - 2.327 0.352 - 90 1 2 0 -0.014 28 0 0 0 1.64E+07 5.11E+05 - - - 4.4036 0.9999 221125_WJC_METTL3_EV_vs_WT_F06.19500.19500.4 3.34E-08 20/84 K.HK[136.11]ELAPYDENWFYTR[166.11].A "sp|P39019|RS19_HUMAN,tr|M0R140|M0R140_HUMAN,tr|M0R2L9|M0R2L9_HUMAN,tr|M0QYF7|M0QYF7_HUMAN" 4 1985.9391 1.08 87363 19500 4 1985.934552 497.492 40S ribosomal protein S19 OS=Homo sapiens OX=9606 GN=RPS19 PE=1 SV=2 5.45 3100.1 - 3.19E+06 - - - -2.281 - 2.812 0.568 - 313.3 1 2 1 -0.0045 15 0 0 0 1.33E+09 1.23E+09 - - - 4.5386 1 221125_WJC_METTL3_EV_vs_WT_F06.19501.19501.3 6.10E-11 21/56 K.HKELAPYDENWFYTR.A "sp|P39019|RS19_HUMAN,tr|M0R140|M0R140_HUMAN,tr|M0R2L9|M0R2L9_HUMAN,tr|M0QYF7|M0QYF7_HUMAN" 4 1967.9166 1.12 87364 19501 3 1967.910375 656.9795 40S ribosomal protein S19 OS=Homo sapiens OX=9606 GN=RPS19 PE=1 SV=2 5.45 3100.2 - 3.80E+06 - - - -3.1693 - 3.662 0.621 - 772.3 1 2 1 -0.0062 15 0 0 0 2.47E+09 2.21E+09 - - - 8.8488 1 221125_WJC_METTL3_EV_vs_WT_F06.19502.19502.3 2.71E-10 20/56 K.HK[136.11]ELAPYDENWFYTR[166.11].A "sp|P39019|RS19_HUMAN,tr|M0R140|M0R140_HUMAN,tr|M0R2L9|M0R2L9_HUMAN,tr|M0QYF7|M0QYF7_HUMAN" 4 1985.9391 1.12 87365 19502 3 1985.938011 662.987 40S ribosomal protein S19 OS=Homo sapiens OX=9606 GN=RPS19 PE=1 SV=2 5.45 3100.3 - 3.88E+06 - - - -0.5393 - 3.331 0.646 - 663.6 1 2 1 -0.0011 15 0 0 0 2.47E+09 2.21E+09 - - - 8.8817 1 221125_WJC_METTL3_EV_vs_WT_F06.19503.19503.3 5.02E-10 20/68 K.EIEGEEIEIVLAK[136.11]PPDK[136.11]K[136.11].R "sp|O43390|HNRPR_HUMAN,tr|B4DT28|B4DT28_HUMAN,tr|A0A6Q8PH35|A0A6Q8PH35_HUMAN,tr|A0A286YEZ8|A0A286YEZ8_HUMAN" 4 2060.1467 1.63 87366 19503 3 2060.143987 687.7229 Heterogeneous nuclear ribonucleoprotein R OS=Homo sapiens OX=9606 GN=HNRNPR PE=1 SV=1 4.42 3100.4 - 1.48E+06 - - - -1.3353 - 3.587 0.659 - 433.2 1 2 0 -0.0028 18 0 0 0 9.47E+07 5.81E+07 - - - 9.0671 0.9999 221125_WJC_METTL3_EV_vs_WT_F06.19506.19506.4 1.18E-06 20/84 K.HKELAPYDENWFYTR.A "sp|P39019|RS19_HUMAN,tr|M0R140|M0R140_HUMAN,tr|M0R2L9|M0R2L9_HUMAN,tr|M0QYF7|M0QYF7_HUMAN" 4 1967.9166 1.08 87367 19506 4 1967.918183 492.9864 40S ribosomal protein S19 OS=Homo sapiens OX=9606 GN=RPS19 PE=1 SV=2 5.45 3100.8 - 4.86E+06 - - - 0.7983 - 2.745 0.554 - 342.6 1 2 1 0.0016 15 0 0 0 1.34E+09 1.23E+09 - - - 4.4089 1 221125_WJC_METTL3_EV_vs_WT_F06.19508.19508.3 2.43E-15 20/76 K.ADEHVIDQGDDGDNFYVIER[166.11].G "sp|P13861|KAP2_HUMAN,tr|H7C1L0|H7C1L0_HUMAN" 2 2316.017 2.05 87369 19508 3 2316.015248 773.0129 cAMP-dependent protein kinase type II-alpha regulatory subunit OS=Homo sapiens OX=9606 GN=PRKAR2A PE=1 SV=2 3.85 3101 - 5.55E+06 - - - -0.7582 - 4.207 0.777 - 464.1 1 2 0 -0.0018 20 0 0 0 4.06E+08 1.98E+08 - - - 10.6879 1 221125_WJC_METTL3_EV_vs_WT_F06.19515.19515.3 1.68E-14 21/88 R.TGDFQLHTNVNDGTEFGGSIYQK[136.11].V "sp|P45880|VDAC2_HUMAN,tr|A0A0A0MR02|A0A0A0MR02_HUMAN" 2 2535.1757 1.32 87374 19515 3 2535.172353 846.0659 Voltage-dependent anion-selective channel protein 2 OS=Homo sapiens OX=9606 GN=VDAC2 PE=1 SV=2 4.53 3101.9 - 4.68E+06 - - - -1.3384 - 4.008 0.706 - 503.8 1 2 0 -0.0034 23 0 0 0 4.59E+08 3.48E+08 - - - 9.6671 1 221125_WJC_METTL3_EV_vs_WT_F06.19516.19516.3 1.56E-12 23/88 R.TGDFQLHTNVNDGTEFGGSIYQK.V "sp|P45880|VDAC2_HUMAN,tr|A0A0A0MR02|A0A0A0MR02_HUMAN" 2 2527.1615 1.32 87375 19516 3 2527.15978 843.3945 Voltage-dependent anion-selective channel protein 2 OS=Homo sapiens OX=9606 GN=VDAC2 PE=1 SV=2 4.53 3101.9 - 7.89E+06 - - - -0.6988 - 4.243 0.671 - 583.1 1 2 0 -0.0018 23 0 0 0 4.59E+08 3.48E+08 - - - 9.411 0.9999 221125_WJC_METTL3_EV_vs_WT_F06.19517.19517.4 8.33E-09 13/102 K.IEWLESHQDADIEDFK[136.11]AK[136.11].K "sp|P11021|BIP_HUMAN,tr|A0A7P0TB36|A0A7P0TB36_HUMAN,tr|A0A7P0TAI0|A0A7P0TAI0_HUMAN" 3 2189.0612 0.56 87376 19517 4 2189.059019 548.2726 Endoplasmic reticulum chaperone BiP OS=Homo sapiens OX=9606 GN=HSPA5 PE=1 SV=2 4.29 3102 - 1.11E+07 - - - -0.9799 - 2.759 0.615 - 100.4 1 2 1 -0.0021 18 0 0 0 7.55E+07 1.34E+08 - - - 4.926 1 221125_WJC_METTL3_EV_vs_WT_F06.19518.19518.4 4.65E-10 16/102 K.IEWLESHQDADIEDFKAK.K "sp|P11021|BIP_HUMAN,tr|A0A7P0TB36|A0A7P0TB36_HUMAN,tr|A0A7P0TAI0|A0A7P0TAI0_HUMAN" 3 2173.0328 0.56 87377 19518 4 2173.030608 544.2655 Endoplasmic reticulum chaperone BiP OS=Homo sapiens OX=9606 GN=HSPA5 PE=1 SV=2 4.29 3102 - 5.52E+06 - - - -0.9922 - 2.903 0.649 - 176.4 1 2 1 -0.0022 18 0 0 0 7.55E+07 1.34E+08 - - - 5.2394 1 221125_WJC_METTL3_EV_vs_WT_F06.19524.19524.3 6.63E-08 14/48 K.ENFPNFLSAC[160.03]DKK.G "sp|Q86SG5|S1A7A_HUMAN,sp|P31151|S10A7_HUMAN" 2 1568.7293 185.19 87381 19524 3 1568.725937 523.9171 Protein S100-A7A OS=Homo sapiens OX=9606 GN=S100A7A PE=1 SV=3 6.16 3102.8 - 9.37E+06 - - - -2.1616 - 2.533 0.547 - 206.3 1 2 0 -0.0034 13 0 0 0 2.42E+08 1.31E+06 - - - 7.1575 1 221125_WJC_METTL3_EV_vs_WT_F06.19525.19525.4 6.86E-09 18/102 K.EIEGEEIEIVLAK[136.11]PPDK[136.11]K[136.11].R "sp|O43390|HNRPR_HUMAN,tr|B4DT28|B4DT28_HUMAN,tr|A0A6Q8PH35|A0A6Q8PH35_HUMAN,tr|A0A286YEZ8|A0A286YEZ8_HUMAN" 4 2060.1467 1.56 87382 19525 4 2060.145569 516.044 Heterogeneous nuclear ribonucleoprotein R OS=Homo sapiens OX=9606 GN=HNRNPR PE=1 SV=1 4.42 3102.9 - 5.74E+06 - - - -0.5674 - 3.261 0.628 - 241.9 1 2 0 -0.0012 18 0 0 0 2.95E+08 1.89E+08 - - - 5.0967 0.9998 221125_WJC_METTL3_EV_vs_WT_F06.19526.19526.3 0.00112 20/92 K.TAPPVTNNSEIQASEVLVAADKEK.V sp|Q96T58|MINT_HUMAN 1 2510.2864 1.76 87383 19526 3 2510.285602 837.7694 Msx2-interacting protein OS=Homo sapiens OX=9606 GN=SPEN PE=1 SV=1 4.41 3102.9 - 4.77E+06 - - - -0.3227 - 3.146 0.457 - 363.6 1 2 1 -0.0008 24 0 0 0 1.06E+08 6.01E+07 - - - 6.2969 1 221125_WJC_METTL3_EV_vs_WT_F06.19528.19528.2 1.81E-10 20/28 K.HKELAPYDENWFYTR.A "sp|P39019|RS19_HUMAN,tr|M0R140|M0R140_HUMAN,tr|M0R2L9|M0R2L9_HUMAN,tr|M0QYF7|M0QYF7_HUMAN" 4 1967.9166 1.15 87385 19528 2 1967.913984 984.9656 40S ribosomal protein S19 OS=Homo sapiens OX=9606 GN=RPS19 PE=1 SV=2 5.45 3103.1 - 2.64E+06 - - - -1.3354 - 3.349 0.629 - 1176 1 2 1 -0.0026 15 0 0 0 1.27E+08 1.11E+08 - - - 6.6575 1 221125_WJC_METTL3_EV_vs_WT_F06.19529.19529.2 2.67E-09 23/28 K.HK[136.11]ELAPYDENWFYTR[166.11].A "sp|P39019|RS19_HUMAN,tr|M0R140|M0R140_HUMAN,tr|M0R2L9|M0R2L9_HUMAN,tr|M0QYF7|M0QYF7_HUMAN" 4 1985.9391 1.15 87386 19529 2 1985.933627 993.9768 40S ribosomal protein S19 OS=Homo sapiens OX=9606 GN=RPS19 PE=1 SV=2 5.45 3103.2 - 2.27E+06 - - - -2.7468 - 3.442 0.632 - 1620.2 1 2 1 -0.0055 15 0 0 0 1.27E+08 1.11E+08 - - - 6.7461 0.9999 221125_WJC_METTL3_EV_vs_WT_F06.19535.19535.4 4.28E-05 13/102 K.EIEGEEIEIVLAKPPDKK.R "sp|O43390|HNRPR_HUMAN,tr|B4DT28|B4DT28_HUMAN,tr|A0A6Q8PH35|A0A6Q8PH35_HUMAN,tr|A0A286YEZ8|A0A286YEZ8_HUMAN" 4 2036.1041 1.56 87390 19535 4 2036.102204 510.0333 Heterogeneous nuclear ribonucleoprotein R OS=Homo sapiens OX=9606 GN=HNRNPR PE=1 SV=1 4.42 3103.9 - 7.77E+06 - - - -0.9499 - 2.27 0.402 - 98.1 1 2 0 -0.0019 18 0 0 0 2.95E+08 1.89E+08 - - - 3.0053 0.9998 221125_WJC_METTL3_EV_vs_WT_F06.19536.19536.3 9.09E-09 18/56 K.AAVEWFDGK[136.11]DFQGSK[136.11].L "sp|Q01844|EWS_HUMAN,tr|B0QYK0|B0QYK0_HUMAN,tr|H7BY36|H7BY36_HUMAN,tr|A0A0D9SFL3|A0A0D9SFL3_HUMAN,tr|C9JGE3|C9JGE3_HUMAN" 5 1699.8177 0.66 87391 19536 3 1699.812185 567.6132 RNA-binding protein EWS OS=Homo sapiens OX=9606 GN=EWSR1 PE=1 SV=1 4.56 3103.9 - 4.36E+06 - - - -3.2362 - 3.569 0.59 - 511.8 1 2 1 -0.0055 15 0 0 0 2.47E+08 3.77E+08 - - - 8.4363 1 221125_WJC_METTL3_EV_vs_WT_F06.19541.19541.3 4.32E-16 31/68 Q.HVQIDVDVSKPDLTAALR.D "sp|P08670|VIME_HUMAN,tr|B0YJC5|B0YJC5_HUMAN,tr|B0YJC4|B0YJC4_HUMAN" 3 1976.0691 2.69 87394 19541 3 1976.063906 659.697 Vimentin OS=Homo sapiens OX=9606 GN=VIM PE=1 SV=4 5.3 3104.4 - 2.62E+06 - - - -2.6234 - 4.861 0.681 - 1084.2 1 1 0 -0.0052 18 0 0 0 6.47E+07 2.41E+07 - - - 10.0685 1 221125_WJC_METTL3_EV_vs_WT_F06.19543.19543.3 4.14E-09 Dec-68 K.EIEGEEIEIVLAKPPDKK.R "sp|O43390|HNRPR_HUMAN,tr|B4DT28|B4DT28_HUMAN,tr|A0A6Q8PH35|A0A6Q8PH35_HUMAN,tr|A0A286YEZ8|A0A286YEZ8_HUMAN" 4 2036.1041 1.64 87396 19543 3 2036.105921 679.7087 Heterogeneous nuclear ribonucleoprotein R OS=Homo sapiens OX=9606 GN=HNRNPR PE=1 SV=1 4.42 3104.6 - 3.36E+06 - - - 0.8757 - 2.707 0.574 - 98.2 1 2 0 0.0018 18 0 0 0 9.52E+07 5.82E+07 - - - 7.4188 1 221125_WJC_METTL3_EV_vs_WT_F06.19544.19544.3 0.00102 25/96 K.SGGSAGGLAEGAGALAPPPPPPQIK.V sp|P50548|ERF_HUMAN 1 2196.1539 2.59 87397 19544 3 2196.154578 733.0586 ETS domain-containing transcription factor ERF OS=Homo sapiens OX=9606 GN=ERF PE=1 SV=2 5.72 3104.7 - 2.36E+06 - - - 0.3169 - 3.922 0.567 - 585.7 1 2 0 0.0007 25 0 0 0 8.44E+07 3.25E+07 - - - 8.0054 1 221125_WJC_METTL3_EV_vs_WT_F06.19555.19555.3 4.28E-13 26/96 M.PAHLLQDDISSSYTTTTTITAPPSR.V sp|O00767|SCD_HUMAN 1 2672.3293 1.26 87403 19555 3 2672.327577 891.7837 Stearoyl-CoA desaturase OS=Homo sapiens OX=9606 GN=SCD PE=1 SV=2 5.22 3106.1 - 2.22E+06 - - - -0.6597 - 4.445 0.682 - 559.3 1 2 0 -0.0018 25 0 0 0 6.44E+07 5.12E+07 - - - 9.5752 1 221125_WJC_METTL3_EV_vs_WT_F06.19566.19566.3 1.30E-08 24/96 K.SGGSAGGLAEGAGALAPPPPPPQIK[136.11].V sp|P50548|ERF_HUMAN 1 2204.1681 2.6 87410 19566 3 2204.161544 735.73 ETS domain-containing transcription factor ERF OS=Homo sapiens OX=9606 GN=ERF PE=1 SV=2 5.72 3107.3 - 1.54E+06 - - - -2.9662 - 3.885 0.633 - 444.9 1 2 0 -0.0065 25 0 0 0 8.47E+07 3.25E+07 - - - 8.7178 0.9239 221125_WJC_METTL3_EV_vs_WT_F06.19567.19567.3 0.299 13/44 K.QKVDSLLENLEK.L "sp|P0DMR1|HNRC4_HUMAN,sp|P07910|HNRPC_HUMAN,sp|O60812|HNRC1_HUMAN,sp|B2RXH8|HNRC2_HUMAN,sp|B7ZW38|HNRC3_HUMAN,tr|B4DY08|B4DY08_HUMAN,tr|G3V5V7|G3V5V7_HUMAN,tr|B2R5W2|B2R5W2_HUMAN,tr|G3V4C1|G3V4C1_HUMAN,tr|A0A0G2JPF8|A0A0G2JPF8_HUMAN,tr|A0A0G2JNQ3|A0A0G2JNQ3_HUMAN,tr|G3V576|G3V576_HUMAN,tr|G3V2D6|G3V2D6_HUMAN,tr|G3V4W0|G3V4W0_HUMAN,tr|G3V2Q1|G3V2Q1_HUMAN" 15 1414.7668 1.75 87411 19567 3 1414.765088 472.5962 Heterogeneous nuclear ribonucleoprotein C-like 4 OS=Homo sapiens OX=9606 GN=HNRNPCL4 PE=3 SV=1 4.68 3107.5 - 1.96E+06 - - - -1.1818 - 2.14 0.078 - 198.6 1 2 1 -0.0017 12 0 0 0 3.33E+07 1.90E+07 - - - 1.518 1 221125_WJC_METTL3_EV_vs_WT_F06.19572.19572.3 8.23E-14 21/88 R.YESGDHVAVYPANDSALVNQLGK.L "sp|P16435|NCPR_HUMAN,tr|H0Y4R2|H0Y4R2_HUMAN,tr|E7EMD0|E7EMD0_HUMAN" 3 2446.1765 1.39 87413 19572 3 2446.1784 816.3994 NADPH--cytochrome P450 reductase OS=Homo sapiens OX=9606 GN=POR PE=1 SV=2 4.54 3108.1 - 2.50E+06 - - - 0.7898 - 4.124 0.694 - 515.7 1 2 0 0.0019 23 0 0 0 4.73E+07 3.39E+07 - - - 9.6007 1 221125_WJC_METTL3_EV_vs_WT_F06.19573.19573.3 6.32E-16 27/96 M.PAHLLQDDISSSYTTTTTITAPPSR[166.11].V sp|O00767|SCD_HUMAN 1 2682.3376 1.26 87414 19573 3 2682.332443 895.1198 Stearoyl-CoA desaturase OS=Homo sapiens OX=9606 GN=SCD PE=1 SV=2 5.22 3108.2 - 2.15E+06 - - - -1.9263 - 4.818 0.698 - 610.6 1 2 0 -0.0052 25 0 0 0 6.44E+07 5.12E+07 - - - 9.938 0.9998 221125_WJC_METTL3_EV_vs_WT_F06.19580.19580.3 0.000136 16/72 K.QGAPTSFLPPEASQLKPDR.Q "sp|Q9BUJ2|HNRL1_HUMAN,tr|M0R0K8|M0R0K8_HUMAN,tr|M0QYZ0|M0QYZ0_HUMAN,tr|A0A0A0MRA5|A0A0A0MRA5_HUMAN,tr|M0QZV6|M0QZV6_HUMAN,tr|B7Z4B8|B7Z4B8_HUMAN,tr|M0QYI8|M0QYI8_HUMAN,tr|M0R203|M0R203_HUMAN" 8 2038.0484 1.82 87419 19580 3 2038.03953 680.3567 Heterogeneous nuclear ribonucleoprotein U-like protein 1 OS=Homo sapiens OX=9606 GN=HNRNPUL1 PE=1 SV=2 6.07 3109.1 - 3.51E+06 - - - -4.3296 - 3.038 0.492 - 223.7 1 2 0 -0.0088 19 0 0 0 1.46E+09 8.03E+08 - - - 6.7529 1 221125_WJC_METTL3_EV_vs_WT_F06.19587.19587.3 5.13E-10 17/72 K.QGAPTSFLPPEASQLK[136.11]PDR[166.11].Q "sp|Q9BUJ2|HNRL1_HUMAN,tr|M0R0K8|M0R0K8_HUMAN,tr|M0QYZ0|M0QYZ0_HUMAN,tr|A0A0A0MRA5|A0A0A0MRA5_HUMAN,tr|M0QZV6|M0QZV6_HUMAN,tr|B7Z4B8|B7Z4B8_HUMAN,tr|M0QYI8|M0QYI8_HUMAN,tr|M0R203|M0R203_HUMAN" 8 2056.0708 1.82 87424 19587 3 2056.069587 686.3642 Heterogeneous nuclear ribonucleoprotein U-like protein 1 OS=Homo sapiens OX=9606 GN=HNRNPUL1 PE=1 SV=2 6.07 3109.9 - 3.53E+06 - - - -0.6016 - 3.289 0.616 - 226.2 1 2 0 -0.0012 19 0 0 0 1.43E+09 7.85E+08 - - - 8.3325 0.9998 221125_WJC_METTL3_EV_vs_WT_F06.19589.19589.3 2.71E-07 18/60 K.ASEVEEILDGNDEKYK.A "sp|Q12824|SNF5_HUMAN,tr|A0A2R8Y5N5|A0A2R8Y5N5_HUMAN,tr|A0A2R8YEE8|A0A2R8YEE8_HUMAN,tr|A0A0U1RQQ2|A0A0U1RQQ2_HUMAN,tr|C9JTA6|C9JTA6_HUMAN,tr|B5MCL5|B5MCL5_HUMAN,tr|A0A0U1RRB8|A0A0U1RRB8_HUMAN,tr|A0A0G2JRV3|A0A0G2JRV3_HUMAN,tr|G5E975|G5E975_HUMAN,tr|A0A0G2JSE9|A0A0G2JSE9_HUMAN" 10 1837.8582 1.26 87426 19589 3 1837.856272 613.6267 SWI\SNF-related matrix-associated actin-dependent regulator of chromatin subfamily B member 1 OS=Homo sapiens OX=9606 GN=SMARCB1 PE=1 SV=2 4.08 3110 - 1.88E+06 - - - -1.0235 - 3.212 0.422 - 364.5 1 2 1 -0.0019 16 0 0 0 2.28E+07 1.81E+07 - - - 6.2385 1 221125_WJC_METTL3_EV_vs_WT_F06.19590.19590.3 2.85E-11 26/60 K.R[166.11]GFAFVTFDDHDSVDK[136.11].L "sp|Q32P51|RA1L2_HUMAN,sp|P09651|ROA1_HUMAN,tr|A0A7I2YQX9|A0A7I2YQX9_HUMAN,tr|F8VZ49|F8VZ49_HUMAN,tr|A0A7I2V3R8|A0A7I2V3R8_HUMAN,tr|F8VTQ5|F8VTQ5_HUMAN,tr|F8W6I7|F8W6I7_HUMAN,tr|H0YH80|H0YH80_HUMAN,tr|A0A7I2V2L6|A0A7I2V2L6_HUMAN,tr|A0A7I2V3W0|A0A7I2V3W0_HUMAN,tr|A0A7I2V5U9|A0A7I2V5U9_HUMAN,tr|A0A2R8Y4L2|A0A2R8Y4L2_HUMAN" 12 1872.8761 1.19 87427 19590 3 1872.875395 625.2993 Heterogeneous nuclear ribonucleoprotein A1-like 2 OS=Homo sapiens OX=9606 GN=HNRNPA1L2 PE=2 SV=2 4.56 3110.1 - 1.74E+06 - - - -0.4015 - 4.34 0.66 - 906.5 1 2 0 -0.0008 16 0 0 0 1.30E+08 1.10E+08 - - - 9.6645 0.9991 221125_WJC_METTL3_EV_vs_WT_F06.19592.19592.4 0.000308 Dec-96 R.IIDK[136.11]NGIHDLDNISFPK[136.11].Q "sp|P49721|PSB2_HUMAN,tr|A0A087WVV1|A0A087WVV1_HUMAN" 2 1954.0495 0.55 87429 19592 4 1954.050217 489.5196 Proteasome subunit beta type-2 OS=Homo sapiens OX=9606 GN=PSMB2 PE=1 SV=1 5.3 3110.3 - 1.30E+06 - - - 0.3787 - 1.992 0.378 - 69 1 2 1 0.0007 17 0 0 0 1.37E+07 2.49E+07 - - - 2.7552 1 221125_WJC_METTL3_EV_vs_WT_F06.19594.19594.4 4.14E-08 17/90 K.R[166.11]GFAFVTFDDHDSVDK[136.11].L "sp|Q32P51|RA1L2_HUMAN,sp|P09651|ROA1_HUMAN,tr|A0A7I2YQX9|A0A7I2YQX9_HUMAN,tr|F8VZ49|F8VZ49_HUMAN,tr|A0A7I2V3R8|A0A7I2V3R8_HUMAN,tr|F8VTQ5|F8VTQ5_HUMAN,tr|F8W6I7|F8W6I7_HUMAN,tr|H0YH80|H0YH80_HUMAN,tr|A0A7I2V2L6|A0A7I2V2L6_HUMAN,tr|A0A7I2V3W0|A0A7I2V3W0_HUMAN,tr|A0A7I2V5U9|A0A7I2V5U9_HUMAN,tr|A0A2R8Y4L2|A0A2R8Y4L2_HUMAN" 12 1872.8761 1.26 87431 19594 4 1872.878685 469.2263 Heterogeneous nuclear ribonucleoprotein A1-like 2 OS=Homo sapiens OX=9606 GN=HNRNPA1L2 PE=2 SV=2 4.56 3110.6 - 823642 - - - 1.3551 - 3.076 0.64 - 239.4 1 2 0 0.0025 16 0 0 0 9.17E+07 7.29E+07 - - - 5.1917 1 221125_WJC_METTL3_EV_vs_WT_F06.19599.19599.3 2.65E-13 22/60 K.RGFAFVTFDDHDSVDK.L "sp|Q32P51|RA1L2_HUMAN,sp|P09651|ROA1_HUMAN,tr|A0A7I2YQX9|A0A7I2YQX9_HUMAN,tr|F8VZ49|F8VZ49_HUMAN,tr|A0A7I2V3R8|A0A7I2V3R8_HUMAN,tr|F8VTQ5|F8VTQ5_HUMAN,tr|F8W6I7|F8W6I7_HUMAN,tr|H0YH80|H0YH80_HUMAN,tr|A0A7I2V2L6|A0A7I2V2L6_HUMAN,tr|A0A7I2V3W0|A0A7I2V3W0_HUMAN,tr|A0A7I2V5U9|A0A7I2V5U9_HUMAN,tr|A0A2R8Y4L2|A0A2R8Y4L2_HUMAN" 12 1854.8537 1.18 87434 19599 3 1854.854115 619.2918 Heterogeneous nuclear ribonucleoprotein A1-like 2 OS=Homo sapiens OX=9606 GN=HNRNPA1L2 PE=2 SV=2 4.56 3111.3 - 3.05E+06 - - - 0.2361 - 4.311 0.703 - 563.9 1 2 0 0.0004 16 0 0 0 1.30E+08 1.10E+08 - - - 10.1268 1 221125_WJC_METTL3_EV_vs_WT_F06.19600.19600.4 1.50E-08 19/90 K.RGFAFVTFDDHDSVDK.L "sp|Q32P51|RA1L2_HUMAN,sp|P09651|ROA1_HUMAN,tr|A0A7I2YQX9|A0A7I2YQX9_HUMAN,tr|F8VZ49|F8VZ49_HUMAN,tr|A0A7I2V3R8|A0A7I2V3R8_HUMAN,tr|F8VTQ5|F8VTQ5_HUMAN,tr|F8W6I7|F8W6I7_HUMAN,tr|H0YH80|H0YH80_HUMAN,tr|A0A7I2V2L6|A0A7I2V2L6_HUMAN,tr|A0A7I2V3W0|A0A7I2V3W0_HUMAN,tr|A0A7I2V5U9|A0A7I2V5U9_HUMAN,tr|A0A2R8Y4L2|A0A2R8Y4L2_HUMAN" 12 1854.8537 1.26 87435 19600 4 1854.853393 464.7207 Heterogeneous nuclear ribonucleoprotein A1-like 2 OS=Homo sapiens OX=9606 GN=HNRNPA1L2 PE=2 SV=2 4.56 3111.3 - 2.23E+06 - - - -0.1531 - 3.239 0.641 - 329.2 1 2 0 -0.0003 16 0 0 0 9.17E+07 7.29E+07 - - - 5.2192 0.9994 221125_WJC_METTL3_EV_vs_WT_F06.19603.19603.4 0.00309 13/96 R.IIDKNGIHDLDNISFPK.Q "sp|P49721|PSB2_HUMAN,tr|A0A087WVV1|A0A087WVV1_HUMAN" 2 1938.0211 0.55 87438 19603 4 1938.019404 485.5125 Proteasome subunit beta type-2 OS=Homo sapiens OX=9606 GN=PSMB2 PE=1 SV=1 5.3 3111.7 - 957263 - - - -0.8633 - 2.324 0.395 - 102.3 1 2 1 -0.0017 17 0 0 0 1.37E+07 2.49E+07 - - - 2.9564 0.9938 221125_WJC_METTL3_EV_vs_WT_F06.19605.19605.3 0.153 Sep-56 K.VQGLEQAVDNFEGKK.T sp|O95817|BAG3_HUMAN 1 1660.842 0.52 87440 19605 3 1660.847711 554.6213 BAG family molecular chaperone regulator 3 OS=Homo sapiens OX=9606 GN=BAG3 PE=1 SV=3 4.68 3111.9 - 463841 - - - 3.4085 - 2.074 0.245 - 86.2 1 2 0 0.0057 15 0 0 0 2.03E+07 3.90E+07 - - - 3.1734 1 221125_WJC_METTL3_EV_vs_WT_F06.19611.19611.3 1.27E-10 20/64 R.IIDK[136.11]NGIHDLDNISFPK[136.11].Q "sp|P49721|PSB2_HUMAN,tr|A0A087WVV1|A0A087WVV1_HUMAN" 2 1954.0495 0.31 87444 19611 3 1954.04787 652.3571 Proteasome subunit beta type-2 OS=Homo sapiens OX=9606 GN=PSMB2 PE=1 SV=1 5.3 3112.7 - 911035 - - - -0.8224 - 3.564 0.613 - 385.6 1 2 1 -0.0016 17 0 0 0 4.85E+06 1.56E+07 - - - 8.5845 1 221125_WJC_METTL3_EV_vs_WT_F06.19613.19613.3 1.33E-06 16/72 K.QTTVSNSQQAYQEAFEISK.K sp|P31946|1433B_HUMAN 1 2158.0178 1.11 87446 19613 3 2158.016006 720.3466 14-3-3 protein beta\alpha OS=Homo sapiens OX=9606 GN=YWHAB PE=1 SV=3 4.53 3113 - 886397 - - - -0.8508 - 3.216 0.489 - 223 1 2 0 -0.0018 19 0 0 0 5.87E+07 5.28E+07 - - - 6.8612 1 221125_WJC_METTL3_EV_vs_WT_F06.19627.19627.2 2.33E-06 24/46 Y.SYGGGSGGGFSASSLGGGFGGGSR.G sp|P35527|K1C9_HUMAN 1 2021.8827 999 87458 19627 2 2021.883253 1011.9486 "Keratin, type I cytoskeletal 9 OS=Homo sapiens OX=9606 GN=KRT9 PE=1 SV=3" 8.46 3114.6 - 1.35E+06 - - - 0.2513 - 4.211 0.689 - 1483.8 1 1 0 0.0005 24 0 0 0 2.40E+08 0.00E+00 - - - 7.6644 1 221125_WJC_METTL3_EV_vs_WT_F06.19628.19628.2 9.60E-15 18/36 K.QTTVSNSQQAYQEAFEISK.K sp|P31946|1433B_HUMAN 1 2158.0178 1.23 87459 19628 2 2158.016844 1080.0162 14-3-3 protein beta\alpha OS=Homo sapiens OX=9606 GN=YWHAB PE=1 SV=3 4.53 3114.7 - 460137 - - - -0.4625 - 3.899 0.724 - 1192.7 1 2 0 -0.001 19 0 0 0 2.21E+07 1.79E+07 - - - 7.7335 1 221125_WJC_METTL3_EV_vs_WT_F06.19630.19630.2 1.21E-15 16/36 K.QTTVSNSQQAYQEAFEISK[136.11].K sp|P31946|1433B_HUMAN 1 2166.032 1.23 87461 19630 2 2166.03312 1084.0233 14-3-3 protein beta\alpha OS=Homo sapiens OX=9606 GN=YWHAB PE=1 SV=3 4.53 3115 - 418018 - - - 0.4977 - 3.914 0.708 - 756.9 1 2 0 0.0011 19 0 0 0 2.21E+07 1.79E+07 - - - 7.6248 1 221125_WJC_METTL3_EV_vs_WT_F06.19638.19638.3 1.06E-09 19/56 K.VQGLEQAVDNFEGK[136.11]K[136.11].T sp|O95817|BAG3_HUMAN 1 1676.8704 0.47 87467 19638 3 1676.871778 559.9641 BAG family molecular chaperone regulator 3 OS=Homo sapiens OX=9606 GN=BAG3 PE=1 SV=3 4.68 3115.9 - 2.12E+06 - - - 0.792 - 3.77 0.541 - 643.9 1 2 0 0.0013 15 0 0 0 1.82E+07 3.88E+07 - - - 8.0341 0.9988 221125_WJC_METTL3_EV_vs_WT_F06.19640.19640.4 0.000261 16/84 R.ELDTVTLEDIK[136.11]EHVK[136.11].Q sp|O43242|PSMD3_HUMAN 1 1783.9538 0.71 87469 19640 4 1783.954293 446.9957 26S proteasome non-ATPase regulatory subunit 3 OS=Homo sapiens OX=9606 GN=PSMD3 PE=1 SV=2 4.5 3116.1 - 887037 - - - 0.2511 - 2.79 0.346 - 208.7 1 2 1 0.0004 15 0 0 0 6.87E+06 9.66E+06 - - - 2.6046 0.9998 221125_WJC_METTL3_EV_vs_WT_F06.19641.19641.4 1.63E-07 16/84 R.GFC[160.03]FITFK[136.11]EEEPVK[136.11]K[136.11].L "sp|Q14103|HNRPD_HUMAN,tr|H0Y8G5|H0Y8G5_HUMAN,tr|H0YA96|H0YA96_HUMAN" 3 1881.9761 1.2 87470 19641 4 1881.97674 471.5013 Heterogeneous nuclear ribonucleoprotein D0 OS=Homo sapiens OX=9606 GN=HNRNPD PE=1 SV=1 6.22 3116.2 - 799348 - - - 0.3358 - 2.462 0.486 - 139.3 1 2 1 0.0006 15 0 0 0 3.79E+08 3.17E+08 - - - 3.7783 1 221125_WJC_METTL3_EV_vs_WT_F06.19643.19643.2 6.33E-06 18-Dec V.TFDDHDSVDK.L "sp|Q32P51|RA1L2_HUMAN,sp|P09651|ROA1_HUMAN,tr|A0A7I2YQX9|A0A7I2YQX9_HUMAN,tr|F8VZ49|F8VZ49_HUMAN,tr|A0A7I2V3R8|A0A7I2V3R8_HUMAN,tr|F8VTQ5|F8VTQ5_HUMAN,tr|F8W6I7|F8W6I7_HUMAN,tr|H0YH80|H0YH80_HUMAN,tr|A0A7I2V2L6|A0A7I2V2L6_HUMAN,tr|A0A7I2V3W0|A0A7I2V3W0_HUMAN,tr|A0A7I2V5U9|A0A7I2V5U9_HUMAN,tr|A0A2R8Y4L2|A0A2R8Y4L2_HUMAN" 12 1177.4887 0.84 87472 19643 2 1177.487548 589.7516 Heterogeneous nuclear ribonucleoprotein A1-like 2 OS=Homo sapiens OX=9606 GN=HNRNPA1L2 PE=2 SV=2 4.13 3116.5 - 693928 - - - -1.0183 - 2.07 0.65 - 398 1 1 0 -0.0012 10 0 0 0 7.58E+06 9.05E+06 - - - 5.8723 0.9861 221125_WJC_METTL3_EV_vs_WT_F06.19645.19645.2 6.45E-05 18-Nov V.TFDDHDSVDK[136.11].L "sp|Q32P51|RA1L2_HUMAN,sp|P09651|ROA1_HUMAN,tr|A0A7I2YQX9|A0A7I2YQX9_HUMAN,tr|F8VZ49|F8VZ49_HUMAN,tr|A0A7I2V3R8|A0A7I2V3R8_HUMAN,tr|F8VTQ5|F8VTQ5_HUMAN,tr|F8W6I7|F8W6I7_HUMAN,tr|H0YH80|H0YH80_HUMAN,tr|A0A7I2V2L6|A0A7I2V2L6_HUMAN,tr|A0A7I2V3W0|A0A7I2V3W0_HUMAN,tr|A0A7I2V5U9|A0A7I2V5U9_HUMAN,tr|A0A2R8Y4L2|A0A2R8Y4L2_HUMAN" 12 1185.5029 0.74 87474 19645 2 1185.505299 593.7587 Heterogeneous nuclear ribonucleoprotein A1-like 2 OS=Homo sapiens OX=9606 GN=HNRNPA1L2 PE=2 SV=2 4.13 3116.8 - 460727 - - - 1.984 - 2.054 0.56 - 288.1 1 1 0 0.0024 10 0 0 0 7.58E+06 1.02E+07 - - - 5.1856 0.9997 221125_WJC_METTL3_EV_vs_WT_F06.19647.19647.3 9.50E-09 16/80 R.DKLNINPEDGMADYSDPSYVK.Q sp|Q99459|CDC5L_HUMAN 1 2370.0686 0.87 87476 19647 3 2370.061883 791.0301 Cell division cycle 5-like protein OS=Homo sapiens OX=9606 GN=CDC5L PE=1 SV=2 4.04 3117 - 370758 - - - -2.816 - 2.996 0.513 - 170.2 1 2 1 -0.0067 21 0 0 0 4.70E+07 5.41E+07 - - - 6.8883 1 221125_WJC_METTL3_EV_vs_WT_F06.19652.19652.2 6.25E-09 17/26 R.VPTANVSVVDLTC[160.03]R[166.11].L "sp|P04406|G3P_HUMAN,tr|E7EUT5|E7EUT5_HUMAN" 2 1539.7954 1.06 87479 19652 2 1539.793898 770.905 Glyceraldehyde-3-phosphate dehydrogenase OS=Homo sapiens OX=9606 GN=GAPDH PE=1 SV=3 5.8 3117.7 - 874148 - - - -1.0066 - 3.486 0.5 - 1074.4 1 2 0 -0.0015 14 0 0 0 2.33E+07 2.19E+07 - - - 5.8672 1 221125_WJC_METTL3_EV_vs_WT_F06.19653.19653.2 2.89E-10 16/26 R.VPTANVSVVDLTC[160.03]R.L "sp|P04406|G3P_HUMAN,tr|E7EUT5|E7EUT5_HUMAN" 2 1529.7872 1.06 87480 19653 2 1529.788179 765.9009 Glyceraldehyde-3-phosphate dehydrogenase OS=Homo sapiens OX=9606 GN=GAPDH PE=1 SV=3 5.8 3117.8 - 1.17E+06 - - - 0.6543 - 3.423 0.605 - 920.2 1 2 0 0.001 14 0 0 0 2.33E+07 2.19E+07 - - - 6.5971 0.9998 221125_WJC_METTL3_EV_vs_WT_F06.19661.19661.3 5.27E-05 17/48 K.ER[166.11]EIAQLVEDVQR[166.11].L "sp|Q13948|CASP_HUMAN,sp|P39880|CUX1_HUMAN,tr|A0A2R8Y852|A0A2R8Y852_HUMAN,tr|A0A2R8YDI1|A0A2R8YDI1_HUMAN" 4 1603.8433 0.96 87486 19661 3 1603.840366 535.6217 Protein CASP OS=Homo sapiens OX=9606 GN=CUX1 PE=1 SV=2 4.41 3118.8 - 1.32E+06 - - - -1.8131 - 2.833 0.473 - 565.1 1 2 1 -0.0029 13 0 0 0 1.82E+07 1.89E+07 - - - 6.636 1 221125_WJC_METTL3_EV_vs_WT_F06.19662.19662.3 8.03E-10 19/108 R.GFGDGYNGYGGGPGGGNFGGSPGYGGGR.G "sp|P22626|ROA2_HUMAN,tr|A0A024RA28|A0A024RA28_HUMAN,tr|A0A7I2V323|A0A7I2V323_HUMAN,tr|A0A7I2V3P7|A0A7I2V3P7_HUMAN" 4 2494.0323 999 87487 19662 3 2495.018261 832.3514 Heterogeneous nuclear ribonucleoproteins A2\B1 OS=Homo sapiens OX=9606 GN=HNRNPA2B1 PE=1 SV=2 5.83 3118.9 - 1.09E+06 - - - 395.3429 - 3.78 0.651 - 200.8 1 2 0 0.986 28 0 0 0 6.01E+06 0.00E+00 - - - 8.5841 1 221125_WJC_METTL3_EV_vs_WT_F06.19663.19663.3 9.39E-10 24/76 R.DGVNK[136.11]DYEETELISTTANYR[166.11].A "sp|Q13123|RED_HUMAN,tr|D6RAY9|D6RAY9_HUMAN,tr|D6REL4|D6REL4_HUMAN,tr|E7EQZ7|E7EQZ7_HUMAN" 4 2335.0935 1.2 87488 19663 3 2335.089953 779.3718 Protein Red OS=Homo sapiens OX=9606 GN=IK PE=1 SV=3 4.18 3119.1 - 1.01E+06 - - - -1.5061 - 4.097 0.664 - 581.4 1 2 1 -0.0035 20 0 0 0 9.97E+07 8.28E+07 - - - 9.3633 1 221125_WJC_METTL3_EV_vs_WT_F06.19666.19666.3 1.41E-05 Sep-76 K.YQGDGIVEDEEETMENNEEK.K "sp|Q9NYF8|BCLF1_HUMAN,tr|H0YF63|H0YF63_HUMAN,tr|E9PK91|E9PK91_HUMAN,tr|H0YF14|H0YF14_HUMAN" 4 2356.9489 11.81 87491 19666 3 2356.951658 786.6569 Bcl-2-associated transcription factor 1 OS=Homo sapiens OX=9606 GN=BCLAF1 PE=1 SV=2 3.62 3119.5 - 521449 - - - 1.1723 - 2.176 0.576 - 52.1 1 2 0 0.0028 20 0 0 0 7.07E+06 5.99E+05 - - - 6.8473 0.9999 221125_WJC_METTL3_EV_vs_WT_F06.19667.19667.2 7.09E-07 Dec-36 K.QGAPTSFLPPEASQLKPDR.Q "sp|Q9BUJ2|HNRL1_HUMAN,tr|M0R0K8|M0R0K8_HUMAN,tr|M0QYZ0|M0QYZ0_HUMAN,tr|A0A0A0MRA5|A0A0A0MRA5_HUMAN,tr|M0QZV6|M0QZV6_HUMAN,tr|B7Z4B8|B7Z4B8_HUMAN,tr|M0QYI8|M0QYI8_HUMAN,tr|M0R203|M0R203_HUMAN" 8 2038.0484 4.36 87492 19667 2 2038.047362 1020.0315 Heterogeneous nuclear ribonucleoprotein U-like protein 1 OS=Homo sapiens OX=9606 GN=HNRNPUL1 PE=1 SV=2 6.07 3119.6 - 262178 - - - -0.4867 - 2.676 0.548 - 170.7 1 2 0 -0.001 19 0 0 0 8.03E+06 1.84E+06 - - - 5.5082 0.9999 221125_WJC_METTL3_EV_vs_WT_F06.19670.19670.4 5.03E-07 16/84 R.GFC[160.03]FITFKEEEPVKK.L "sp|Q14103|HNRPD_HUMAN,tr|H0Y8G5|H0Y8G5_HUMAN,tr|H0YA96|H0YA96_HUMAN" 3 1857.9335 1.2 87493 19670 4 1857.933121 465.4907 Heterogeneous nuclear ribonucleoprotein D0 OS=Homo sapiens OX=9606 GN=HNRNPD PE=1 SV=1 6.22 3120 - 9.33E+06 - - - -0.2083 - 2.739 0.606 - 164.7 1 2 1 -0.0004 15 0 0 0 3.79E+08 3.17E+08 - - - 4.861 1 221125_WJC_METTL3_EV_vs_WT_F06.19672.19672.3 6.31E-08 16/56 R.GFC[160.03]FITFK[136.11]EEEPVK[136.11]K[136.11].L "sp|Q14103|HNRPD_HUMAN,tr|H0Y8G5|H0Y8G5_HUMAN,tr|H0YA96|H0YA96_HUMAN" 3 1881.9761 1.2 87495 19672 3 1881.975451 628.3326 Heterogeneous nuclear ribonucleoprotein D0 OS=Homo sapiens OX=9606 GN=HNRNPD PE=1 SV=1 6.22 3120.2 - 3.68E+06 - - - -0.3491 - 3.09 0.623 - 290.3 1 2 1 -0.0007 15 0 0 0 1.78E+08 1.49E+08 - - - 8.4295 1 221125_WJC_METTL3_EV_vs_WT_F06.19674.19674.3 4.96E-10 17/84 K.AAIHQILTENTPVSEQLSVPQR.S "sp|Q9Y2W6|TDRKH_HUMAN,tr|F6TB26|F6TB26_HUMAN,tr|Q5SZR4|Q5SZR4_HUMAN" 3 2430.2867 1.53 87497 19674 3 2430.285085 811.1028 Tudor and KH domain-containing protein OS=Homo sapiens OX=9606 GN=TDRKH PE=1 SV=2 5.4 3120.3 - 1.87E+06 - - - -0.6592 - 3.045 0.642 - 287.5 1 2 0 -0.0016 22 0 0 0 9.74E+07 6.35E+07 - - - 8.3371 1 221125_WJC_METTL3_EV_vs_WT_F06.19677.19677.2 1.27E-11 20/34 K.TAESQTPTPSATSFFSGK[136.11].S "sp|P55265|DSRAD_HUMAN,tr|A0A3B3ITG9|A0A3B3ITG9_HUMAN,tr|A0A3B3IRQ9|A0A3B3IRQ9_HUMAN,tr|A0A3B3ISU1|A0A3B3ISU1_HUMAN,tr|A0A7P0Z4K3|A0A7P0Z4K3_HUMAN,tr|A0A3B3ISX1|A0A3B3ISX1_HUMAN,tr|A0A7P0Z4F9|A0A7P0Z4F9_HUMAN" 7 1850.8778 0.85 87500 19677 2 1850.877762 926.4462 Double-stranded RNA-specific adenosine deaminase OS=Homo sapiens OX=9606 GN=ADAR PE=1 SV=4 5.66 3120.7 - 1.09E+06 - - - -0.0059 - 3.767 0.699 - 1076 1 2 0 0 18 0 0 0 7.97E+07 9.35E+07 - - - 7.4645 1 221125_WJC_METTL3_EV_vs_WT_F06.19680.19680.3 1.10E-08 18/56 R.GFC[160.03]FITFKEEEPVKK.L "sp|Q14103|HNRPD_HUMAN,tr|H0Y8G5|H0Y8G5_HUMAN,tr|H0YA96|H0YA96_HUMAN" 3 1857.9335 1.2 87501 19680 3 1857.934226 620.3184 Heterogeneous nuclear ribonucleoprotein D0 OS=Homo sapiens OX=9606 GN=HNRNPD PE=1 SV=1 6.22 3121.1 - 5.09E+06 - - - 0.3865 - 3.214 0.674 - 400.7 1 2 1 0.0007 15 0 0 0 1.78E+08 1.49E+08 - - - 9.1007 1 221125_WJC_METTL3_EV_vs_WT_F06.19681.19681.3 5.72E-07 24/76 R.DGVNKDYEETELISTTANYR.A "sp|Q13123|RED_HUMAN,tr|D6RAY9|D6RAY9_HUMAN,tr|D6REL4|D6REL4_HUMAN,tr|E7EQZ7|E7EQZ7_HUMAN" 4 2317.071 1.2 87502 19681 3 2317.07273 773.3643 Protein Red OS=Homo sapiens OX=9606 GN=IK PE=1 SV=3 4.18 3121.2 - 2.89E+06 - - - 0.7466 - 4.35 0.654 - 608 1 2 1 0.0017 20 0 0 0 1.00E+08 8.31E+07 - - - 9.3977 1 221125_WJC_METTL3_EV_vs_WT_F06.19683.19683.3 3.56E-11 19/84 K.AAIHQILTENTPVSEQLSVPQR[166.11].S "sp|Q9Y2W6|TDRKH_HUMAN,tr|F6TB26|F6TB26_HUMAN,tr|Q5SZR4|Q5SZR4_HUMAN" 3 2440.295 1.53 87504 19683 3 2440.292679 814.4389 Tudor and KH domain-containing protein OS=Homo sapiens OX=9606 GN=TDRKH PE=1 SV=2 5.4 3121.3 - 1.60E+06 - - - -0.9335 - 3.532 0.631 - 335.2 1 2 0 -0.0023 22 0 0 0 9.74E+07 6.35E+07 - - - 8.5661 0.9999 221125_WJC_METTL3_EV_vs_WT_F06.19684.19684.3 7.21E-06 16/68 K.TAESQTPTPSATSFFSGK.S "sp|P55265|DSRAD_HUMAN,tr|A0A3B3ITG9|A0A3B3ITG9_HUMAN,tr|A0A3B3IRQ9|A0A3B3IRQ9_HUMAN,tr|A0A3B3ISU1|A0A3B3ISU1_HUMAN,tr|A0A7P0Z4K3|A0A7P0Z4K3_HUMAN,tr|A0A3B3ISX1|A0A3B3ISX1_HUMAN,tr|A0A7P0Z4F9|A0A7P0Z4F9_HUMAN" 7 1842.8636 1.23 87505 19684 3 1842.862981 615.2951 Double-stranded RNA-specific adenosine deaminase OS=Homo sapiens OX=9606 GN=ADAR PE=1 SV=4 5.66 3121.5 - 1.54E+06 - - - -0.3212 - 2.474 0.411 - 236.7 1 2 0 -0.0006 18 0 0 0 9.36E+07 7.64E+07 - - - 5.3777 1 221125_WJC_METTL3_EV_vs_WT_F06.19685.19685.3 4.19E-07 19/108 R.GFGDGYNGYGGGPGGGNFGGSPGYGGGR[166.11].G "sp|P22626|ROA2_HUMAN,tr|A0A024RA28|A0A024RA28_HUMAN,tr|A0A7I2V323|A0A7I2V323_HUMAN,tr|A0A7I2V3P7|A0A7I2V3P7_HUMAN" 4 2504.0405 -1 87506 19685 3 2505.019861 835.6875 Heterogeneous nuclear ribonucleoproteins A2\B1 OS=Homo sapiens OX=9606 GN=HNRNPA2B1 PE=1 SV=2 5.83 3121.5 - 1.35E+06 - - - 391.0991 - 3.403 0.687 - 242.8 1 2 0 0.9793 28 0 0 0 0.00E+00 0.00E+00 - - - 8.7456 0.9979 221125_WJC_METTL3_EV_vs_WT_F06.19688.19688.4 0.0159 11/108 R.GLLQDDAHPTLVTYADHSK[136.11].L "sp|Q86U44|MTA70_HUMAN,tr|F5H6D8|F5H6D8_HUMAN,tr|H0YFV6|H0YFV6_HUMAN,tr|B4DTN4|B4DTN4_HUMAN" 4 2088.0367 0.03 87507 19688 4 2088.03423 523.0165 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 5.13 3121.9 - 2.81E+06 - - - -1.1987 - 2.145 0.261 - 88.3 1 2 0 -0.0025 19 0 0 0 2.79E+06 9.40E+07 - - - 1.7552 1 221125_WJC_METTL3_EV_vs_WT_F06.19689.19689.3 1.21E-09 21/76 R.GGC[160.03]NITAIQDVTGAHIDVDK.Q "sp|Q8IWZ3|ANKH1_HUMAN,tr|A0A0A0MQZ8|A0A0A0MQZ8_HUMAN,tr|H0Y472|H0Y472_HUMAN,tr|H0Y7Y3|H0Y7Y3_HUMAN,tr|H0Y4P6|H0Y4P6_HUMAN,tr|H0Y785|H0Y785_HUMAN" 6 2083.0004 1.46 87508 19689 3 2083.001259 695.3407 Ankyrin repeat and KH domain-containing protein 1 OS=Homo sapiens OX=9606 GN=ANKHD1 PE=1 SV=1 4.41 3122 - 3.80E+06 - - - 0.4037 - 4.01 0.563 - 498.4 1 2 0 0.0008 20 0 0 0 2.06E+08 1.41E+08 - - - 8.1859 1 221125_WJC_METTL3_EV_vs_WT_F06.19692.19692.2 3.50E-12 18/34 K.TAESQTPTPSATSFFSGK.S "sp|P55265|DSRAD_HUMAN,tr|A0A3B3ITG9|A0A3B3ITG9_HUMAN,tr|A0A3B3IRQ9|A0A3B3IRQ9_HUMAN,tr|A0A3B3ISU1|A0A3B3ISU1_HUMAN,tr|A0A7P0Z4K3|A0A7P0Z4K3_HUMAN,tr|A0A3B3ISX1|A0A3B3ISX1_HUMAN,tr|A0A7P0Z4F9|A0A7P0Z4F9_HUMAN" 7 1842.8636 0.85 87511 19692 2 1842.862687 922.4391 Double-stranded RNA-specific adenosine deaminase OS=Homo sapiens OX=9606 GN=ADAR PE=1 SV=4 5.66 3122.3 - 1.40E+06 - - - -0.4808 - 3.695 0.703 - 807.2 1 2 0 -0.0009 18 0 0 0 7.97E+07 9.35E+07 - - - 7.4464 1 221125_WJC_METTL3_EV_vs_WT_F06.19698.19698.3 5.50E-15 26/96 R.SYGPAPGAGHVQEESNLSLQALESR.Q sp|Q13155|AIMP2_HUMAN 1 2596.2518 0.77 87515 19698 3 2596.253137 866.4245 Aminoacyl tRNA synthase complex-interacting multifunctional protein 2 OS=Homo sapiens OX=9606 GN=AIMP2 PE=1 SV=2 4.75 3123.1 - 1.60E+06 - - - 0.5312 - 4.233 0.683 - 673.2 1 2 0 0.0014 25 0 0 0 1.45E+08 1.87E+08 - - - 9.474 1 221125_WJC_METTL3_EV_vs_WT_F06.19700.19700.3 4.66E-06 17/68 K.TAESQTPTPSATSFFSGK[136.11].S "sp|P55265|DSRAD_HUMAN,tr|A0A3B3ITG9|A0A3B3ITG9_HUMAN,tr|A0A3B3IRQ9|A0A3B3IRQ9_HUMAN,tr|A0A3B3ISU1|A0A3B3ISU1_HUMAN,tr|A0A7P0Z4K3|A0A7P0Z4K3_HUMAN,tr|A0A3B3ISX1|A0A3B3ISX1_HUMAN,tr|A0A7P0Z4F9|A0A7P0Z4F9_HUMAN" 7 1850.8778 1.38 87517 19700 3 1850.876971 617.9665 Double-stranded RNA-specific adenosine deaminase OS=Homo sapiens OX=9606 GN=ADAR PE=1 SV=4 5.66 3123.3 - 2.30E+06 - - - -0.4333 - 3.199 0.525 - 346.2 1 2 0 -0.0008 18 0 0 0 9.24E+07 6.70E+07 - - - 7.2886 0.9997 221125_WJC_METTL3_EV_vs_WT_F06.19701.19701.4 4.16E-05 18/132 R.IVSR[166.11]PEELR[166.11]EDDVGTGAGLLEIK[136.11].K "sp|P49368|TCPG_HUMAN,tr|B4DUR8|B4DUR8_HUMAN" 2 2523.3539 0.25 87518 19701 4 2523.352903 631.8457 T-complex protein 1 subunit gamma OS=Homo sapiens OX=9606 GN=CCT3 PE=1 SV=4 4.36 3123.4 - 1.51E+06 - - - -0.384 - 2.402 0.442 - 127.2 1 2 1 -0.001 23 0 0 0 8.78E+07 3.53E+08 - - - 3.3568 1 221125_WJC_METTL3_EV_vs_WT_F06.19702.19702.2 1.24E-14 16/38 R.FSSC[160.03]GGGGGSFGAGGGFGSR.S sp|P04264|K2C1_HUMAN 1 1764.7274 80.57 87519 19702 2 1764.724308 883.371 "Keratin, type II cytoskeletal 1 OS=Homo sapiens OX=9606 GN=KRT1 PE=1 SV=6" 8.25 3123.5 - 546556 - - - -1.7697 - 3.47 0.808 - 771.8 1 2 0 -0.0031 20 0 0 0 1.34E+07 1.66E+05 - - - 8.0667 0.9997 221125_WJC_METTL3_EV_vs_WT_F06.19709.19709.4 9.63E-05 18/84 R.VREEVPLELVEAHVK.K sp|Q92922|SMRC1_HUMAN 1 1745.9676 2.86 87524 19709 4 1745.966793 437.4992 SWI\SNF complex subunit SMARCC1 OS=Homo sapiens OX=9606 GN=SMARCC1 PE=1 SV=3 4.91 3124.3 - 805755 - - - -0.4536 - 2.662 0.439 - 186.3 1 2 1 -0.0008 15 0 0 0 1.78E+07 6.21E+06 - - - 3.3972 0.9981 221125_WJC_METTL3_EV_vs_WT_F06.19711.19711.3 8.79E-06 Aug-80 K.GFDNPEENSSEFPVTFKEESK.F "sp|Q8IWI9|MGAP_HUMAN,tr|H3BU53|H3BU53_HUMAN" 2 2416.0707 0.41 87526 19711 3 2416.079776 806.3642 MAX gene-associated protein OS=Homo sapiens OX=9606 GN=MGA PE=1 SV=4 4.14 3124.6 - 440882 - - - 3.7706 - 1.791 0.518 - 43.4 1 2 1 0.0091 21 0 0 0 9.54E+06 2.35E+07 - - - 5.7098 0.9893 221125_WJC_METTL3_EV_vs_WT_F06.19712.19712.4 0.0517 14/102 K.KMSADNQLQVIFITNDRR.N "sp|Q9Y2L1|RRP44_HUMAN,tr|F2Z2C0|F2Z2C0_HUMAN" 2 2148.111 4.67 87527 19712 4 2148.110971 538.035 Exosome complex exonuclease RRP44 OS=Homo sapiens OX=9606 GN=DIS3 PE=1 SV=2 8.75 3124.7 - 375477 - - - 0 - 2.338 0.187 - 159.8 1 2 0 0 18 0 0 0 5.87E+06 1.26E+06 - - - 1.1446 1 221125_WJC_METTL3_EV_vs_WT_F06.19716.19716.3 4.63E-07 29/96 R.SYGPAPGAGHVQEESNLSLQALESR[166.11].Q sp|Q13155|AIMP2_HUMAN 1 2606.26 0.74 87529 19716 3 2606.25619 869.7606 Aminoacyl tRNA synthase complex-interacting multifunctional protein 2 OS=Homo sapiens OX=9606 GN=AIMP2 PE=1 SV=2 4.75 3125.2 - 4.75E+06 - - - -1.4726 - 4.33 0.624 - 770.8 1 2 0 -0.0038 25 0 0 0 1.45E+08 1.96E+08 - - - 8.8677 1 221125_WJC_METTL3_EV_vs_WT_F06.19720.19720.3 2.13E-05 21/52 R.KVESLQEEIAFLKK.L "sp|P08670|VIME_HUMAN,tr|B0YJC5|B0YJC5_HUMAN,tr|B0YJC4|B0YJC4_HUMAN" 3 1660.94 1.74 87533 19720 3 1660.938336 554.6539 Vimentin OS=Homo sapiens OX=9606 GN=VIM PE=1 SV=4 6.23 3125.6 - 1.17E+06 - - - -0.9856 - 3.766 0.564 - 636.8 1 2 0 -0.0016 14 0 0 0 6.77E+08 3.89E+08 - - - 8.3515 0.9999 221125_WJC_METTL3_EV_vs_WT_F06.19721.19721.3 1.97E-07 23/88 R.IVSR[166.11]PEELR[166.11]EDDVGTGAGLLEIK[136.11].K "sp|P49368|TCPG_HUMAN,tr|B4DUR8|B4DUR8_HUMAN" 2 2523.3539 0.23 87534 19721 3 2523.353859 842.1252 T-complex protein 1 subunit gamma OS=Homo sapiens OX=9606 GN=CCT3 PE=1 SV=4 4.36 3125.8 - 1.08E+06 - - - -0.0052 - 3.465 0.502 - 340.7 1 2 1 0 23 0 0 0 1.95E+07 8.58E+07 - - - 7.0521 0.9998 221125_WJC_METTL3_EV_vs_WT_F06.19722.19722.2 8.20E-05 14/28 R.NFILDQTNVSAAAQR[166.11].R "sp|Q00839|HNRPU_HUMAN,tr|A0A1W2PQL0|A0A1W2PQL0_HUMAN,tr|A0A1W2PPL4|A0A1W2PPL4_HUMAN,tr|A0A1W2PQ74|A0A1W2PQ74_HUMAN,tr|Q5RI18|Q5RI18_HUMAN,tr|A0A1W2PP35|A0A1W2PP35_HUMAN,tr|A0A1W2PPS1|A0A1W2PPS1_HUMAN,tr|A0A1W2PRZ7|A0A1W2PRZ7_HUMAN,tr|A0A1W2PPH7|A0A1W2PPH7_HUMAN,tr|A0A1W2PQD4|A0A1W2PQD4_HUMAN,tr|A0A1W2PP34|A0A1W2PP34_HUMAN,tr|A0A1X7SBS1|A0A1X7SBS1_HUMAN" 12 1656.8459 1.18 87535 19722 2 1656.844244 829.4302 Heterogeneous nuclear ribonucleoprotein U OS=Homo sapiens OX=9606 GN=HNRNPU PE=1 SV=6 5.84 3125.9 - 1.02E+06 - - - -1.0013 - 2.677 0.448 - 678.4 1 2 0 -0.0017 15 0 0 0 2.42E+07 2.06E+07 - - - 4.7703 0.9998 221125_WJC_METTL3_EV_vs_WT_F06.19723.19723.4 3.67E-09 15/78 R.K[136.11]VESLQEEIAFLK[136.11]K[136.11].L "sp|P08670|VIME_HUMAN,tr|B0YJC5|B0YJC5_HUMAN,tr|B0YJC4|B0YJC4_HUMAN" 3 1684.9826 1.72 87536 19723 4 1684.979424 422.2529 Vimentin OS=Homo sapiens OX=9606 GN=VIM PE=1 SV=4 6.23 3126 - 775741 - - - -1.8689 - 2.715 0.403 - 206.6 1 2 0 -0.0031 14 0 0 0 3.67E+08 2.14E+08 - - - 3.0963 0.9999 221125_WJC_METTL3_EV_vs_WT_F06.19724.19724.3 0.000145 13/64 K.EDNSLLNQGFLQAKPEK.A sp|P10244|MYBB_HUMAN 1 1929.9796 3.79 87537 19724 3 1929.98182 644.3338 Myb-related protein B OS=Homo sapiens OX=9606 GN=MYBL2 PE=1 SV=1 4.68 3126.1 - 760534 - - - 1.1472 - 2.758 0.431 - 180.9 1 2 0 0.0022 17 0 0 0 1.07E+07 2.84E+06 - - - 5.9076 1 221125_WJC_METTL3_EV_vs_WT_F06.19729.19729.2 1.69E-08 17/28 R.NFILDQTNVSAAAQR.R "sp|Q00839|HNRPU_HUMAN,tr|A0A1W2PQL0|A0A1W2PQL0_HUMAN,tr|A0A1W2PPL4|A0A1W2PPL4_HUMAN,tr|A0A1W2PQ74|A0A1W2PQ74_HUMAN,tr|Q5RI18|Q5RI18_HUMAN,tr|A0A1W2PP35|A0A1W2PP35_HUMAN,tr|A0A1W2PPS1|A0A1W2PPS1_HUMAN,tr|A0A1W2PRZ7|A0A1W2PRZ7_HUMAN,tr|A0A1W2PPH7|A0A1W2PPH7_HUMAN,tr|A0A1W2PQD4|A0A1W2PQD4_HUMAN,tr|A0A1W2PP34|A0A1W2PP34_HUMAN,tr|A0A1X7SBS1|A0A1X7SBS1_HUMAN" 12 1646.8376 1.18 87540 19729 2 1646.837694 824.4261 Heterogeneous nuclear ribonucleoprotein U OS=Homo sapiens OX=9606 GN=HNRNPU PE=1 SV=6 5.84 3126.7 - 1.19E+06 - - - 0.037 - 3.277 0.555 - 978.8 1 2 0 0.0001 15 0 0 0 2.42E+07 2.06E+07 - - - 6.0583 0.9999 221125_WJC_METTL3_EV_vs_WT_F06.19730.19730.4 7.96E-09 22/132 R.IVSRPEELREDDVGTGAGLLEIK.K "sp|P49368|TCPG_HUMAN,tr|B4DUR8|B4DUR8_HUMAN" 2 2495.3231 0.25 87541 19730 4 2495.322467 624.8381 T-complex protein 1 subunit gamma OS=Homo sapiens OX=9606 GN=CCT3 PE=1 SV=4 4.36 3126.8 - 1.91E+06 - - - -0.2665 - 3.386 0.549 - 264.8 1 2 1 -0.0007 23 0 0 0 8.78E+07 3.53E+08 - - - 4.3995 1 221125_WJC_METTL3_EV_vs_WT_F06.19732.19732.4 1.16E-12 22/120 R.KVIQVDEMIVEEEEEEENERK.N sp|Q53HL2|BOREA_HUMAN 1 2603.2272 12.53 87543 19732 4 2603.227906 651.8141 Borealin OS=Homo sapiens OX=9606 GN=CDCA8 PE=1 SV=2 4.08 3127 - 1.25E+06 - - - 0.2547 - 4.294 0.683 - 436.6 1 2 0 0.0007 21 0 0 0 1.30E+08 1.03E+07 - - - 5.6525 1 221125_WJC_METTL3_EV_vs_WT_F06.19733.19733.3 5.55E-07 13/68 K.SSSAEGHTDAVLDLSWNK[136.11].L "sp|Q13610|PWP1_HUMAN,tr|B4DJV5|B4DJV5_HUMAN" 2 1923.9054 1 87544 19733 3 1923.902786 642.3091 Periodic tryptophan protein 1 homolog OS=Homo sapiens OX=9606 GN=PWP1 PE=1 SV=1 4.53 3127.1 - 1.19E+06 - - - -1.3509 - 2.646 0.586 - 161.4 1 2 0 -0.0026 18 0 0 0 3.92E+07 3.90E+07 - - - 7.4956 1 221125_WJC_METTL3_EV_vs_WT_F06.19734.19734.3 1.76E-08 14/68 K.SSSAEGHTDAVLDLSWNK.L "sp|Q13610|PWP1_HUMAN,tr|B4DJV5|B4DJV5_HUMAN" 2 1915.8912 0.99 87545 19734 3 1915.889086 639.6377 Periodic tryptophan protein 1 homolog OS=Homo sapiens OX=9606 GN=PWP1 PE=1 SV=1 4.53 3127.2 - 913090 - - - -1.0956 - 3.08 0.581 - 266.8 1 2 0 -0.0021 18 0 0 0 3.91E+07 3.93E+07 - - - 7.8182 1 221125_WJC_METTL3_EV_vs_WT_F06.19739.19739.4 2.77E-08 17/90 K.RGFAFVTFDDHDTVDK.L "sp|P51991|ROA3_HUMAN,tr|A0A7I2V5D8|A0A7I2V5D8_HUMAN,tr|A0A7I2V2R3|A0A7I2V2R3_HUMAN,tr|A0A7I2V4J6|A0A7I2V4J6_HUMAN,tr|A0A7I2V4G0|A0A7I2V4G0_HUMAN,tr|A0A7I2V402|A0A7I2V402_HUMAN" 6 1868.8693 1.3 87548 19739 4 1868.869336 468.2246 Heterogeneous nuclear ribonucleoprotein A3 OS=Homo sapiens OX=9606 GN=HNRNPA3 PE=1 SV=2 4.56 3127.8 - 1.23E+06 - - - 0.0048 - 2.704 0.571 - 302.2 1 2 0 0 16 0 0 0 5.01E+07 3.86E+07 - - - 4.5464 0.9999 221125_WJC_METTL3_EV_vs_WT_F06.19744.19744.4 0.00106 13/78 R.KVESLQEEIAFLKK.L "sp|P08670|VIME_HUMAN,tr|B0YJC5|B0YJC5_HUMAN,tr|B0YJC4|B0YJC4_HUMAN" 3 1660.94 1.71 87551 19744 4 1660.938422 416.2423 Vimentin OS=Homo sapiens OX=9606 GN=VIM PE=1 SV=4 6.23 3128.5 - 6.04E+06 - - - -0.9338 - 2.29 0.42 - 164.7 1 2 0 -0.0016 14 0 0 0 3.68E+08 2.15E+08 - - - 3.1828 1 221125_WJC_METTL3_EV_vs_WT_F06.19746.19746.3 7.24E-10 18/84 K.LAVEEFVHATSEGEAPGGC[160.03]EGR.G sp|Q5C9Z4|NOM1_HUMAN 1 2301.0332 1.18 87553 19746 3 2302.030507 768.0183 Nucleolar MIF4G domain-containing protein 1 OS=Homo sapiens OX=9606 GN=NOM1 PE=1 SV=1 4.32 3128.7 - 519193 - - - 433.4279 - 3.411 0.666 - 261.4 1 2 0 0.9973 22 0 0 0 9.48E+06 8.00E+06 - - - 8.598 0.999 221125_WJC_METTL3_EV_vs_WT_F06.19757.19757.4 6.84E-05 21/120 R.EK[136.11]LQEEMLQR[166.11]EEAENTLQSFR[166.11].Q "sp|P08670|VIME_HUMAN,tr|B0YJC4|B0YJC4_HUMAN" 2 2635.2906 1.73 87560 19757 4 2635.296821 659.8299 Vimentin OS=Homo sapiens OX=9606 GN=VIM PE=1 SV=4 4.48 3130 - 1.66E+06 - - - 2.3531 - 3.05 0.401 - 207.9 1 2 2 0.0062 21 0 0 0 2.10E+08 1.22E+08 - - - 3.0833 0.9989 221125_WJC_METTL3_EV_vs_WT_F06.19758.19758.3 7.01E-10 26/104 K.SPLPSYPGANPQPAFGAAEGQPPGAAK.P "sp|Q96HA1|P121A_HUMAN,sp|A6NF01|P121B_HUMAN,sp|A8CG34|P121C_HUMAN" 3 2576.266 3.21 87561 19758 3 2576.263014 859.7626 Nuclear envelope pore membrane protein POM 121 OS=Homo sapiens OX=9606 GN=POM121 PE=1 SV=2 5.72 3130.1 - 1.30E+06 - - - -1.1404 - 3.604 0.618 - 410.2 1 1 0 -0.0029 27 0 0 0 4.44E+07 1.39E+07 - - - 8.3788 0.9996 221125_WJC_METTL3_EV_vs_WT_F06.19759.19759.4 1.04E-08 20/114 R.VPTANVSVVDLTC[160.03]R[166.11]LEK[136.11]PAK[136.11].Y "sp|P04406|G3P_HUMAN,tr|E7EUT5|E7EUT5_HUMAN" 2 2222.2303 0.84 87562 19759 4 2222.228905 556.5649 Glyceraldehyde-3-phosphate dehydrogenase OS=Homo sapiens OX=9606 GN=GAPDH PE=1 SV=3 8.17 3130.3 - 1.29E+06 - - - -0.6318 - 3.534 0.408 - 329.6 1 2 1 -0.0014 20 0 0 0 2.01E+07 2.41E+07 - - - 3.1989 0.9997 221125_WJC_METTL3_EV_vs_WT_F06.19760.19760.3 0.0142 22/88 R.IVSRPEELREDDVGTGAGLLEIK.K "sp|P49368|TCPG_HUMAN,tr|B4DUR8|B4DUR8_HUMAN" 2 2495.3231 0.23 87563 19760 3 2495.322008 832.7817 T-complex protein 1 subunit gamma OS=Homo sapiens OX=9606 GN=CCT3 PE=1 SV=4 4.36 3130.4 - 1.25E+06 - - - -0.4504 - 2.72 0.428 - 281.4 1 2 1 -0.0011 23 0 0 0 1.95E+07 8.58E+07 - - - 5.6589 1 221125_WJC_METTL3_EV_vs_WT_F06.19763.19763.3 6.92E-11 17/80 R.EK[136.11]LQEEMLQR[166.11]EEAENTLQSFR[166.11].Q "sp|P08670|VIME_HUMAN,tr|B0YJC4|B0YJC4_HUMAN" 2 2635.2906 5.46 87566 19763 3 2635.291395 879.4375 Vimentin OS=Homo sapiens OX=9606 GN=VIM PE=1 SV=4 4.48 3130.8 - 642694 - - - 0.2941 - 3.607 0.644 - 259.7 1 2 2 0.0008 21 0 0 0 2.19E+08 4.02E+07 - - - 8.7954 1 221125_WJC_METTL3_EV_vs_WT_F06.19766.19766.3 5.97E-08 16/52 R.K[136.11]VESLQEEIAFLK[136.11]K[136.11].L "sp|P08670|VIME_HUMAN,tr|B0YJC5|B0YJC5_HUMAN,tr|B0YJC4|B0YJC4_HUMAN" 3 1684.9826 1.74 87567 19766 3 1684.981641 562.6681 Vimentin OS=Homo sapiens OX=9606 GN=VIM PE=1 SV=4 6.23 3131.2 - 2.06E+07 - - - -0.5531 - 3.057 0.613 - 361.6 1 2 0 -0.0009 14 0 0 0 6.77E+08 3.89E+08 - - - 8.3437 0.898 221125_WJC_METTL3_EV_vs_WT_F06.19768.19768.2 0.537 14-Aug Q.EEIAFLKK.L "sp|P08670|VIME_HUMAN,sp|P17661|DESM_HUMAN,tr|B0YJC5|B0YJC5_HUMAN,tr|B0YJC4|B0YJC4_HUMAN" 4 976.5593 1.81 87569 19768 2 976.558038 489.2869 Vimentin OS=Homo sapiens OX=9606 GN=VIM PE=1 SV=4 6.24 3131.3 - 769515 - - - -1.3261 - 1.609 0.222 - 186.4 1 1 0 -0.0013 8 0 0 0 1.94E+07 1.07E+07 - - - 2.1147 1 221125_WJC_METTL3_EV_vs_WT_F06.19774.19774.4 6.58E-07 15/90 K.R[166.11]GFAFVTFDDHDTVDK[136.11].L "sp|P51991|ROA3_HUMAN,tr|A0A7I2V5D8|A0A7I2V5D8_HUMAN,tr|A0A7I2V2R3|A0A7I2V2R3_HUMAN,tr|A0A7I2V4J6|A0A7I2V4J6_HUMAN,tr|A0A7I2V4G0|A0A7I2V4G0_HUMAN,tr|A0A7I2V402|A0A7I2V402_HUMAN" 6 1886.8918 1.42 87573 19774 4 1886.892242 472.7302 Heterogeneous nuclear ribonucleoprotein A3 OS=Homo sapiens OX=9606 GN=HNRNPA3 PE=1 SV=2 4.56 3132 - 2.40E+06 - - - 0.2358 - 2.55 0.524 - 202.2 1 2 0 0.0004 16 0 0 0 5.49E+07 3.88E+07 - - - 4.1165 1 221125_WJC_METTL3_EV_vs_WT_F06.19776.19776.3 4.70E-07 20/52 R.K[136.11]VESLQEEIAFLKK[136.11].L "sp|P08670|VIME_HUMAN,tr|B0YJC5|B0YJC5_HUMAN,tr|B0YJC4|B0YJC4_HUMAN" 3 1676.9684 - 87575 19776 3 1676.969707 559.9967 Vimentin OS=Homo sapiens OX=9606 GN=VIM PE=1 SV=4 6.23 3132.3 - 781952 - - - 0.7955 - 3.677 0.595 - 555.3 1 2 0 0.0013 14 0 0 0 - - - - - 8.6337 1 221125_WJC_METTL3_EV_vs_WT_F06.19777.19777.3 1.40E-11 28/100 R.GQVTLYEHNNELVTGSSYESPPPDFR.G sp|Q9NRG9|AAAS_HUMAN 1 2935.3624 2.42 87576 19777 3 2935.357235 979.4614 Aladin OS=Homo sapiens OX=9606 GN=AAAS PE=1 SV=1 4.4 3132.4 - 702574 - - - -1.7701 - 4.551 0.707 - 675.7 1 2 0 -0.0052 26 0 0 0 1.90E+07 7.83E+06 - - - 9.9072 1 221125_WJC_METTL3_EV_vs_WT_F06.19782.19782.3 1.55E-10 17/68 K.YVHYEIDAC[160.03]MDSEAPGSK[136.11].D "sp|Q86U44|MTA70_HUMAN,tr|H0YFV6|H0YFV6_HUMAN" 2 2078.8805 0 87579 19782 3 2079.878073 693.9674 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 4.31 3133 - 2.80E+06 - - - 479.8645 - 3.189 0.685 - 306.4 1 2 0 0.9976 18 0 0 0 2.67E+05 9.72E+07 - - - 8.7885 1 221125_WJC_METTL3_EV_vs_WT_F06.19783.19783.4 1.40E-07 16/96 K.NQAVC[160.03]HDYDIHFYPTFR[166.11].Y sp|Q6ZRP7|QSOX2_HUMAN 1 2191.9773 1.26 87580 19783 4 2191.977145 549.0016 Sulfhydryl oxidase 2 OS=Homo sapiens OX=9606 GN=QSOX2 PE=1 SV=3 5.98 3133.1 - 2.37E+06 - - - -0.0835 - 2.904 0.597 - 217.3 1 2 0 -0.0002 17 0 0 0 4.97E+07 3.93E+07 - - - 4.7924 1 221125_WJC_METTL3_EV_vs_WT_F06.19784.19784.4 2.16E-07 17/96 K.NQAVC[160.03]HDYDIHFYPTFR.Y sp|Q6ZRP7|QSOX2_HUMAN 1 2181.9691 1.26 87581 19784 4 2181.968401 546.4995 Sulfhydryl oxidase 2 OS=Homo sapiens OX=9606 GN=QSOX2 PE=1 SV=3 5.98 3133.1 - 2.85E+06 - - - -0.3011 - 2.253 0.541 - 237.3 1 2 0 -0.0007 17 0 0 0 4.97E+07 3.93E+07 - - - 4.2167 1 221125_WJC_METTL3_EV_vs_WT_F06.19785.19785.3 3.96E-15 20/60 K.SHDDGNIDLESDSFLK.F sp|P18583|SON_HUMAN 1 1790.7959 1.97 87582 19785 3 1790.795144 597.9392 Protein SON OS=Homo sapiens OX=9606 GN=SON PE=1 SV=4 4.03 3133.2 - 1.79E+06 - - - -0.4155 - 3.526 0.682 - 657.5 1 2 0 -0.0007 16 0 0 0 1.68E+08 8.55E+07 - - - 9.3768 0.9999 221125_WJC_METTL3_EV_vs_WT_F06.19786.19786.3 6.57E-07 15/76 K.VDK[136.11]IEELDQENEAALENGIK[136.11].N "sp|P43243|MATR3_HUMAN,tr|B3KM87|B3KM87_HUMAN,tr|A8MXP9|A8MXP9_HUMAN,tr|A0A0R4J2E8|A0A0R4J2E8_HUMAN,tr|D6REM6|D6REM6_HUMAN" 5 2272.1405 1.95 87583 19786 3 2272.14187 758.3875 Matrin-3 OS=Homo sapiens OX=9606 GN=MATR3 PE=1 SV=2 4 3133.2 - 1.48E+06 - - - 0.5871 - 2.856 0.511 - 200.1 1 2 1 0.0013 20 0 0 0 2.78E+07 1.42E+07 - - - 6.7827 0.9999 221125_WJC_METTL3_EV_vs_WT_F06.19787.19787.3 1.05E-09 22/88 K.QSK[136.11]PVTTPEEIAQVATISANGDK[136.11].E "sp|P10809|CH60_HUMAN,tr|A0A7I2V599|A0A7I2V599_HUMAN,tr|E7EXB4|E7EXB4_HUMAN,tr|A0A7I2YQ71|A0A7I2YQ71_HUMAN,tr|E7ESH4|E7ESH4_HUMAN,tr|A0A7I2V5M1|A0A7I2V5M1_HUMAN,tr|A0A7I2V5K3|A0A7I2V5K3_HUMAN,tr|A0A7I2V369|A0A7I2V369_HUMAN" 8 2399.2515 1.49 87584 19787 3 2399.260187 800.7578 "60 kDa heat shock protein, mitochondrial OS=Homo sapiens OX=9606 GN=HSPD1 PE=1 SV=2" 4.68 3133.4 - 998226 - - - 3.6274 - 3.67 0.528 - 500.7 1 2 0 0.0087 23 0 0 0 9.99E+07 6.69E+07 - - - 7.4744 0.9999 221125_WJC_METTL3_EV_vs_WT_F06.19792.19792.3 4.46E-06 14/48 R.SIFDHIKLPQASK.S "sp|Q9NYF8|BCLF1_HUMAN,tr|E9PKI6|E9PKI6_HUMAN,tr|A0A1W2PQ43|A0A1W2PQ43_HUMAN,tr|E9PK91|E9PK91_HUMAN,tr|E9PJA7|E9PJA7_HUMAN,tr|E9PK09|E9PK09_HUMAN,tr|E9PQN2|E9PQN2_HUMAN" 7 1482.8195 2.11 87587 19792 3 1482.819557 495.2804 Bcl-2-associated transcription factor 1 OS=Homo sapiens OX=9606 GN=BCLAF1 PE=1 SV=2 8.33 3134 - 1.10E+06 - - - 0.0627 - 2.442 0.559 - 174.6 1 2 1 0.0001 13 0 0 0 1.03E+09 4.89E+08 - - - 7.193 1 221125_WJC_METTL3_EV_vs_WT_F06.19796.19796.3 9.39E-12 20/64 K.NQAVC[160.03]HDYDIHFYPTFR.Y sp|Q6ZRP7|QSOX2_HUMAN 1 2181.9691 2.56 87591 19796 3 2181.97455 728.3303 Sulfhydryl oxidase 2 OS=Homo sapiens OX=9606 GN=QSOX2 PE=1 SV=3 5.98 3134.6 - 655422 - - - 2.517 - 3.806 0.66 - 565.5 1 2 0 0.0055 17 0 0 0 1.26E+07 4.93E+06 - - - 9.2734 1 221125_WJC_METTL3_EV_vs_WT_F06.19797.19797.3 1.56E-09 21/104 K.SPLPSYPGANPQPAFGAAEGQPPGAAK[136.11].P "sp|Q96HA1|P121A_HUMAN,sp|A6NF01|P121B_HUMAN,sp|A8CG34|P121C_HUMAN" 3 2584.2802 3.21 87592 19797 3 2584.278428 862.434 Nuclear envelope pore membrane protein POM 121 OS=Homo sapiens OX=9606 GN=POM121 PE=1 SV=2 5.72 3134.7 - 645555 - - - -0.6671 - 3.66 0.678 - 222.1 1 1 0 -0.0017 27 0 0 0 4.44E+07 1.39E+07 - - - 9.0835 0.9973 221125_WJC_METTL3_EV_vs_WT_F06.19798.19798.3 0.00112 Dec-68 R.NDIHEDNLLEC[160.03]PPEELAR[166.11].D "sp|Q14527|HLTF_HUMAN,tr|H7C5K0|H7C5K0_HUMAN,tr|A0A0C4DGA6|A0A0C4DGA6_HUMAN" 3 2172.9985 0.16 87593 19798 3 2173.004428 725.3401 Helicase-like transcription factor OS=Homo sapiens OX=9606 GN=HLTF PE=1 SV=2 4.08 3134.8 - 611527 - - - 2.7202 - 2.148 0.266 - 138.4 1 2 0 0.0059 18 0 0 0 1.12E+06 7.01E+06 - - - 3.4078 1 221125_WJC_METTL3_EV_vs_WT_F06.19801.19801.3 1.34E-10 21/88 K.QSKPVTTPEEIAQVATISANGDK.E "sp|P10809|CH60_HUMAN,tr|A0A7I2V599|A0A7I2V599_HUMAN,tr|E7EXB4|E7EXB4_HUMAN,tr|A0A7I2YQ71|A0A7I2YQ71_HUMAN,tr|E7ESH4|E7ESH4_HUMAN,tr|A0A7I2V5M1|A0A7I2V5M1_HUMAN,tr|A0A7I2V5K3|A0A7I2V5K3_HUMAN,tr|A0A7I2V369|A0A7I2V369_HUMAN" 8 2383.2231 1.57 87594 19801 3 2383.223111 795.415 "60 kDa heat shock protein, mitochondrial OS=Homo sapiens OX=9606 GN=HSPD1 PE=1 SV=2" 4.68 3135.2 - 1.52E+06 - - - 0.0113 - 4.073 0.609 - 442.7 1 2 0 0 23 0 0 0 4.75E+07 3.02E+07 - - - 8.6243 1 221125_WJC_METTL3_EV_vs_WT_F06.19802.19802.3 6.96E-12 23/64 R.DRSDC[160.03]LGEHLYVMVNAK.F "sp|P54105|ICLN_HUMAN,tr|E9PJF4|E9PJF4_HUMAN,tr|J3KN38|J3KN38_HUMAN,tr|E9PMI6|E9PMI6_HUMAN" 4 2005.935 3.67 87595 19802 3 2005.936599 669.6523 Methylosome subunit pICln OS=Homo sapiens OX=9606 GN=CLNS1A PE=1 SV=1 5.38 3135.3 - 1.04E+06 - - - 0.8066 - 3.786 0.688 - 914.5 1 2 1 0.0016 17 0 0 0 1.56E+07 4.24E+06 - - - 9.5734 1 221125_WJC_METTL3_EV_vs_WT_F06.19805.19805.3 7.57E-07 18/72 K.AEAQQVEALPGPSLDQWHR.S "sp|Q66PJ3|AR6P4_HUMAN,tr|F8WCT1|F8WCT1_HUMAN,tr|H7BZV4|H7BZV4_HUMAN,tr|F5GYV5|F5GYV5_HUMAN,tr|A0A0C4DG62|A0A0C4DG62_HUMAN" 5 2131.0447 0.64 87598 19805 3 2131.046191 711.3555 ADP-ribosylation factor-like protein 6-interacting protein 4 OS=Homo sapiens OX=9606 GN=ARL6IP4 PE=1 SV=2 4.65 3135.7 - 653428 - - - 0.7156 - 3.39 0.556 - 448.5 1 2 0 0.0015 19 0 0 0 7.19E+06 1.13E+07 - - - 7.7378 1 221125_WJC_METTL3_EV_vs_WT_F06.19808.19808.2 7.53E-12 23/30 K.SHDDGNIDLESDSFLK.F sp|P18583|SON_HUMAN 1 1790.7959 4.59 87601 19808 2 1790.797496 896.4052 Protein SON OS=Homo sapiens OX=9606 GN=SON PE=1 SV=4 4.03 3136.1 - 385620 - - - 0.8979 - 4.9 0.787 - 1458.6 1 2 0 0.0016 16 0 0 0 1.30E+07 2.83E+06 - - - 8.7605 1 221125_WJC_METTL3_EV_vs_WT_F06.19811.19811.3 5.96E-11 17/60 K.SHDDGNIDLESDSFLK[136.11].F sp|P18583|SON_HUMAN 1 1798.8101 1.93 87602 19811 3 1798.80884 600.6106 Protein SON OS=Homo sapiens OX=9606 GN=SON PE=1 SV=4 4.03 3136.5 - 5.62E+06 - - - -0.6938 - 3.407 0.759 - 477.9 1 2 0 -0.0012 16 0 0 0 1.64E+08 8.53E+07 - - - 10.1471 0.9904 221125_WJC_METTL3_EV_vs_WT_F06.19814.19814.3 0.000608 14/40 K.EK[136.11]FEEMIQQIK[136.11].E "sp|P48643|TCPE_HUMAN,tr|E9PCA1|E9PCA1_HUMAN,tr|B7ZAR1|B7ZAR1_HUMAN,tr|E7ENZ3|E7ENZ3_HUMAN" 4 1437.7509 0.55 87605 19814 3 1437.751353 480.2576 T-complex protein 1 subunit epsilon OS=Homo sapiens OX=9606 GN=CCT5 PE=1 SV=1 4.79 3136.9 - 880944 - - - 0.3485 - 2.358 0.163 - 370.5 1 2 1 0.0005 11 0 0 0 1.93E+07 3.48E+07 - - - 2.7941 0.9999 221125_WJC_METTL3_EV_vs_WT_F06.19819.19819.3 2.81E-10 19/76 K.VDKIEELDQENEAALENGIK.N "sp|P43243|MATR3_HUMAN,tr|B3KM87|B3KM87_HUMAN,tr|A8MXP9|A8MXP9_HUMAN,tr|A0A0R4J2E8|A0A0R4J2E8_HUMAN,tr|D6REM6|D6REM6_HUMAN" 5 2256.1121 1.91 87608 19819 3 2256.111613 753.0447 Matrin-3 OS=Homo sapiens OX=9606 GN=MATR3 PE=1 SV=2 4 3137.5 - 948294 - - - -0.2318 - 2.924 0.575 - 345.6 1 2 1 -0.0005 20 0 0 0 2.78E+07 1.45E+07 - - - 7.5535 0.9988 221125_WJC_METTL3_EV_vs_WT_F06.19820.19820.3 8.45E-05 13/40 K.EKFEEMIQQIK.E "sp|P48643|TCPE_HUMAN,tr|E9PCA1|E9PCA1_HUMAN,tr|B7ZAR1|B7ZAR1_HUMAN,tr|E7ENZ3|E7ENZ3_HUMAN" 4 1421.7225 0.55 87609 19820 3 1421.723889 474.9148 T-complex protein 1 subunit epsilon OS=Homo sapiens OX=9606 GN=CCT5 PE=1 SV=1 4.79 3137.6 - 682816 - - - 1.0107 - 2.385 0.309 - 313.5 1 2 1 0.0014 11 0 0 0 1.93E+07 3.48E+07 - - - 4.4539 0.9999 221125_WJC_METTL3_EV_vs_WT_F06.19822.19822.3 8.23E-05 14/72 K.AEAQQVEALPGPSLDQWHR[166.11].S "sp|Q66PJ3|AR6P4_HUMAN,tr|F8WCT1|F8WCT1_HUMAN,tr|H7BZV4|H7BZV4_HUMAN,tr|F5GYV5|F5GYV5_HUMAN,tr|A0A0C4DG62|A0A0C4DG62_HUMAN" 5 2141.0529 0.63 87611 19822 3 2141.051578 714.6916 ADP-ribosylation factor-like protein 6-interacting protein 4 OS=Homo sapiens OX=9606 GN=ARL6IP4 PE=1 SV=2 4.65 3137.9 - 638962 - - - -0.6343 - 2.605 0.405 - 187 1 2 0 -0.0014 19 0 0 0 7.19E+06 1.14E+07 - - - 5.4072 0.9999 221125_WJC_METTL3_EV_vs_WT_F06.19823.19823.3 6.57E-07 15/56 K.LVEALC[160.03]AEHQINLIK.V sp|P25398|RS12_HUMAN 1 1749.9447 1.92 87612 19823 3 1749.948335 584.3222 40S ribosomal protein S12 OS=Homo sapiens OX=9606 GN=RPS12 PE=1 SV=3 5.4 3138 - 633852 - - - 2.0538 - 2.355 0.505 - 102.9 1 2 0 0.0036 15 0 0 0 6.08E+06 3.16E+06 - - - 6.4043 0.9975 221125_WJC_METTL3_EV_vs_WT_F06.19831.19831.2 4.75E-05 13/20 K.EK[136.11]FEEMIQQIK[136.11].E "sp|P48643|TCPE_HUMAN,tr|E9PCA1|E9PCA1_HUMAN,tr|B7ZAR1|B7ZAR1_HUMAN,tr|E7ENZ3|E7ENZ3_HUMAN" 4 1437.7509 0.62 87618 19831 2 1437.749435 719.8827 T-complex protein 1 subunit epsilon OS=Homo sapiens OX=9606 GN=CCT5 PE=1 SV=1 4.79 3139 - 592511 - - - -0.9856 - 2.217 0.403 - 361.8 1 2 1 -0.0014 11 0 0 0 7.00E+06 1.13E+07 - - - 4.1709 0.9997 221125_WJC_METTL3_EV_vs_WT_F06.19833.19833.4 0.00964 14/72 R.NYDVMK[136.11]DFEEMR[166.11]K[136.11].A sp|P09669|COX6C_HUMAN 1 1729.8014 1.04 87620 19833 4 1729.799678 433.4576 Cytochrome c oxidase subunit 6C OS=Homo sapiens OX=9606 GN=COX6C PE=1 SV=2 4.78 3139.3 - 362958 - - - -0.9938 - 2.612 0.431 - 170.2 1 2 1 -0.0017 13 0 0 0 8.50E+06 8.19E+06 - - - 3.3329 1 221125_WJC_METTL3_EV_vs_WT_F06.19834.19834.3 6.92E-07 Dec-44 R.EHALLAYTLGVK[136.11].Q "sp|Q05639|EF1A2_HUMAN,sp|P68104|EF1A1_HUMAN,sp|Q5VTE0|EF1A3_HUMAN,tr|A0A2R8Y488|A0A2R8Y488_HUMAN,tr|A0A7I2V659|A0A7I2V659_HUMAN,tr|A0A7I2V3H3|A0A7I2V3H3_HUMAN,tr|A0A2U3TZH3|A0A2U3TZH3_HUMAN,tr|A0A7I2V5N4|A0A7I2V5N4_HUMAN,tr|A0A087WVQ9|A0A087WVQ9_HUMAN,tr|A0A087WV01|A0A087WV01_HUMAN,tr|A0A2R8Y660|A0A2R8Y660_HUMAN" 11 1321.7485 2.45 87621 19834 3 1321.746117 441.5901 Elongation factor 1-alpha 2 OS=Homo sapiens OX=9606 GN=EEF1A2 PE=1 SV=1 6.85 3139.4 - 271762 - - - -1.8309 - 2.683 0.482 - 207 1 2 0 -0.0024 12 0 0 0 9.34E+06 3.81E+06 - - - 6.6488 1 221125_WJC_METTL3_EV_vs_WT_F06.19837.19837.3 0.000144 20/72 K.QGAPTSFLPPEASQLKPDR.Q "sp|Q9BUJ2|HNRL1_HUMAN,tr|M0R0K8|M0R0K8_HUMAN,tr|M0QYZ0|M0QYZ0_HUMAN,tr|A0A0A0MRA5|A0A0A0MRA5_HUMAN,tr|M0QZV6|M0QZV6_HUMAN,tr|B7Z4B8|B7Z4B8_HUMAN,tr|M0QYI8|M0QYI8_HUMAN,tr|M0R203|M0R203_HUMAN" 8 2038.0484 1.82 87623 19837 3 2038.049011 680.3567 Heterogeneous nuclear ribonucleoprotein U-like protein 1 OS=Homo sapiens OX=9606 GN=HNRNPUL1 PE=1 SV=2 6.07 3139.7 - 6.70E+06 - - - 0.3224 - 3.583 0.473 - 361 1 2 0 0.0007 19 0 0 0 1.46E+09 8.03E+08 - - - 6.9487 0.9999 221125_WJC_METTL3_EV_vs_WT_F06.19839.19839.3 1.69E-05 17/76 R.FSGVPDRFSGSGSGTDFTLK.L "sp|A2NJV5|KV229_HUMAN,sp|A0A075B6S2|KVD29_HUMAN,sp|A0A0A0MRZ7|KVD26_HUMAN" 3 2060.9803 73.36 87624 19839 3 2060.982156 688.0007 Immunoglobulin kappa variable 2-29 OS=Homo sapiens OX=9606 GN=IGKV2-29 PE=3 SV=2 5.96 3139.9 - 3.62E+06 - - - 0.884 - 2.619 0.533 - 254.8 1 2 1 0.0018 20 0 0 0 3.54E+08 4.82E+06 - - - 6.8177 1 221125_WJC_METTL3_EV_vs_WT_F06.19840.19840.3 3.26E-11 15/96 K.LVQDVANNTNEEAGDGTTTATVLAR.S "sp|P10809|CH60_HUMAN,tr|C9JL25|C9JL25_HUMAN,tr|A0A7I2V2X6|A0A7I2V2X6_HUMAN,tr|A0A7I2YQK6|A0A7I2YQK6_HUMAN,tr|A0A7I2V599|A0A7I2V599_HUMAN,tr|E7EXB4|E7EXB4_HUMAN,tr|A0A7I2YQ71|A0A7I2YQ71_HUMAN,tr|E7ESH4|E7ESH4_HUMAN,tr|A0A7I2V5M1|A0A7I2V5M1_HUMAN,tr|A0A7I2V5K3|A0A7I2V5K3_HUMAN,tr|A0A7I2V369|A0A7I2V369_HUMAN" 11 2559.2413 1.79 87625 19840 3 2559.242625 854.0877 "60 kDa heat shock protein, mitochondrial OS=Homo sapiens OX=9606 GN=HSPD1 PE=1 SV=2" 3.92 3140.1 - 621956 - - - 0.5361 - 3.315 0.704 - 206 1 2 0 0.0014 25 0 0 0 3.03E+07 1.69E+07 - - - 9.1457 0.9998 221125_WJC_METTL3_EV_vs_WT_F06.19843.19843.4 6.93E-05 20/120 K.KTPLSTGGTLAFVSPSLAVHK.S sp|Q86YP4|P66A_HUMAN 1 2110.1786 1.28 87628 19843 4 2110.182293 528.5519 Transcriptional repressor p66-alpha OS=Homo sapiens OX=9606 GN=GATAD2A PE=1 SV=1 10 3140.4 - 652612 - - - 1.7311 - 3.419 0.399 - 279.3 1 2 0 0.0037 21 0 0 0 1.89E+07 1.48E+07 - - - 3.1044 1 221125_WJC_METTL3_EV_vs_WT_F06.19844.19844.3 6.80E-07 16/84 K.FTFHLEPQAQATQVSDVPATSR.R sp|O60826|CCD22_HUMAN 1 2429.1975 0.86 87629 19844 3 2429.196335 810.7398 Coiled-coil domain-containing protein 22 OS=Homo sapiens OX=9606 GN=CCDC22 PE=1 SV=1 5.32 3140.6 - 651539 - - - -0.4952 - 3.609 0.578 - 300.8 1 2 0 -0.0012 22 0 0 0 1.01E+07 1.17E+07 - - - 8.0266 0.9987 221125_WJC_METTL3_EV_vs_WT_F06.19845.19845.3 1.88E-05 14/72 K.INVPELPTPDEDNK[136.11]LEVQK[136.11].V sp|O43264|ZW10_HUMAN 1 2193.15 1.31 87630 19845 3 2193.15686 732.0573 Centromere\kinetochore protein zw10 homolog OS=Homo sapiens OX=9606 GN=ZW10 PE=1 SV=3 4.18 3140.7 - 381473 - - - 3.1375 - 2.291 0.448 - 137.1 1 2 1 0.0069 19 0 0 0 2.18E+07 1.66E+07 - - - 5.5695 0.9996 221125_WJC_METTL3_EV_vs_WT_F06.19846.19846.3 7.63E-05 Oct-56 K.HK[136.11]ELAPYDENWFYTR[166.11].A "sp|P39019|RS19_HUMAN,tr|M0R140|M0R140_HUMAN,tr|M0R2L9|M0R2L9_HUMAN,tr|M0QYF7|M0QYF7_HUMAN" 4 1985.9391 1.13 87631 19846 3 1985.938366 662.987 40S ribosomal protein S19 OS=Homo sapiens OX=9606 GN=RPS19 PE=1 SV=2 5.45 3140.8 - 329395 - - - -0.3605 - 2.257 0.42 - 162.6 1 2 1 -0.0007 15 0 0 0 1.55E+07 1.37E+07 - - - 5.3465 1 221125_WJC_METTL3_EV_vs_WT_F06.19858.19858.3 5.13E-08 18/64 K.ITNEKGEC[160.03]IVSDFTIGR.K "sp|P52948|NUP98_HUMAN,tr|A0A3B3ITD8|A0A3B3ITD8_HUMAN" 2 1937.9517 2.77 87641 19858 3 1937.950289 646.9912 Nuclear pore complex protein Nup98-Nup96 OS=Homo sapiens OX=9606 GN=NUP98 PE=1 SV=4 4.68 3142.3 - 777261 - - - -0.7162 - 3.666 0.581 - 380.9 1 2 1 -0.0014 17 0 0 0 9.17E+06 3.31E+06 - - - 8.2991 0.9998 221125_WJC_METTL3_EV_vs_WT_F06.19859.19859.4 0.00279 17/72 R.NYDVMKDFEEMRK.A sp|P09669|COX6C_HUMAN 1 1703.7647 1.04 87642 19859 4 1703.76569 426.9485 Cytochrome c oxidase subunit 6C OS=Homo sapiens OX=9606 GN=COX6C PE=1 SV=2 4.78 3142.4 - 666048 - - - 0.5652 - 3.01 0.474 - 242.3 1 2 1 0.001 13 0 0 0 8.50E+06 8.19E+06 - - - 3.76 0.9998 221125_WJC_METTL3_EV_vs_WT_F06.19860.19860.3 1.32E-05 Dec-40 K.LKVPEWVDTVK.L "sp|P39019|RS19_HUMAN,tr|M0R140|M0R140_HUMAN,tr|M0R2L9|M0R2L9_HUMAN,tr|M0QYF7|M0QYF7_HUMAN" 4 1312.7391 1.12 87643 19860 3 1312.739066 438.587 40S ribosomal protein S19 OS=Homo sapiens OX=9606 GN=RPS19 PE=1 SV=2 6.07 3142.5 - 454494 - - - -0.0168 - 2.447 0.469 - 243 1 2 1 0 11 0 0 0 3.24E+07 2.88E+07 - - - 6.311 0.8429 221125_WJC_METTL3_EV_vs_WT_F06.19861.19861.4 0.00175 Dec-96 S.PSELFAQHIVTIVHHVK.E "sp|Q9Y2W1|TR150_HUMAN,tr|A0A3B3ITZ9|A0A3B3ITZ9_HUMAN" 2 1954.0789 0.86 87644 19861 4 1954.077879 489.527 Thyroid hormone receptor-associated protein 3 OS=Homo sapiens OX=9606 GN=THRAP3 PE=1 SV=2 7.42 3142.7 - 430833 - - - -0.5051 - 2.057 0.275 - 91.9 1 1 0 -0.001 17 0 0 0 4.53E+06 5.25E+06 - - - 1.8697 0.9997 221125_WJC_METTL3_EV_vs_WT_F06.19862.19862.4 0.000505 Oct-66 R.DILQDYTHEFHK.T "sp|O95249|GOSR1_HUMAN,tr|B4DQA8|B4DQA8_HUMAN,tr|E9PCW1|E9PCW1_HUMAN,tr|K7EJC8|K7EJC8_HUMAN,tr|G5E9T8|G5E9T8_HUMAN" 5 1544.726 1.59 87645 19862 4 1544.728508 387.1888 Golgi SNAP receptor complex member 1 OS=Homo sapiens OX=9606 GN=GOSR1 PE=1 SV=1 5.21 3142.8 - 407887 - - - 1.6514 - 1.94 0.38 - 55.7 1 2 0 0.0026 12 0 0 0 6.71E+06 4.21E+06 - - - 2.7836 1 221125_WJC_METTL3_EV_vs_WT_F06.19865.19865.3 9.78E-08 22/64 R.HVSIQEAESYAESVGAK[136.11].H sp|Q9UL25|RAB21_HUMAN 1 1811.8781 1.25 87646 19865 3 1811.879584 604.9666 Ras-related protein Rab-21 OS=Homo sapiens OX=9606 GN=RAB21 PE=1 SV=3 4.75 3143.2 - 1.81E+06 - - - 0.8146 - 4.067 0.675 - 863.4 1 2 0 0.0015 17 0 0 0 1.37E+08 1.10E+08 - - - 9.6093 0.9999 221125_WJC_METTL3_EV_vs_WT_F06.19866.19866.3 5.55E-06 19/72 K.QQQTVFIHPNSSLFEQQPR.W "sp|O60231|DHX16_HUMAN,tr|Q5SQH5|Q5SQH5_HUMAN,tr|A0A140T8Y5|A0A140T8Y5_HUMAN" 3 2283.1396 7.14 87647 19866 3 2283.145307 762.0538 Pre-mRNA-splicing factor ATP-dependent RNA helicase DHX16 OS=Homo sapiens OX=9606 GN=DHX16 PE=1 SV=2 6.75 3143.3 - 1.17E+06 - - - 2.4869 - 3.47 0.498 - 333.2 1 2 0 0.0057 19 0 0 0 8.25E+07 1.16E+07 - - - 7.1473 1 221125_WJC_METTL3_EV_vs_WT_F06.19867.19867.3 5.42E-13 21/64 R.HVSIQEAESYAESVGAK.H sp|Q9UL25|RAB21_HUMAN 1 1803.8639 1.26 87648 19867 3 1803.866351 602.2952 Ras-related protein Rab-21 OS=Homo sapiens OX=9606 GN=RAB21 PE=1 SV=3 4.75 3143.4 - 2.22E+06 - - - 1.3543 - 4.075 0.679 - 728.9 1 2 0 0.0024 17 0 0 0 1.38E+08 1.10E+08 - - - 9.6586 0.9999 221125_WJC_METTL3_EV_vs_WT_F06.19869.19869.3 8.30E-06 17/72 K.QQQTVFIHPNSSLFEQQPR[166.11].W "sp|O60231|DHX16_HUMAN,tr|Q5SQH5|Q5SQH5_HUMAN,tr|A0A140T8Y5|A0A140T8Y5_HUMAN" 3 2293.1479 7.05 87650 19869 3 2293.14827 765.3899 Pre-mRNA-splicing factor ATP-dependent RNA helicase DHX16 OS=Homo sapiens OX=9606 GN=DHX16 PE=1 SV=2 6.75 3143.6 - 806669 - - - 0.1618 - 3.127 0.332 - 287.5 1 2 0 0.0004 19 0 0 0 7.67E+07 1.09E+07 - - - 5.0423 0.9969 221125_WJC_METTL3_EV_vs_WT_F06.19870.19870.4 0.00106 16/114 R.QHVVYGPWNLPQSSYSHLTR.Q sp|Q16610|ECM1_HUMAN 1 2368.1713 131.32 87651 19870 4 2368.18035 593.0501 Extracellular matrix protein 1 OS=Homo sapiens OX=9606 GN=ECM1 PE=1 SV=2 8.6 3143.7 - 531336 - - - 3.8371 - 2.587 0.32 - 137.7 1 2 0 0.0091 20 0 0 0 3.88E+07 2.95E+05 - - - 2.3265 0.9981 221125_WJC_METTL3_EV_vs_WT_F06.19871.19871.3 0.00497 Sep-88 R.TGDFQLHTNVNDGTEFGGSIYQK.V "sp|P45880|VDAC2_HUMAN,tr|A0A0A0MR02|A0A0A0MR02_HUMAN" 2 2527.1615 1.72 87652 19871 3 2527.16236 843.3945 Voltage-dependent anion-selective channel protein 2 OS=Homo sapiens OX=9606 GN=VDAC2 PE=1 SV=2 4.53 3143.9 - 475845 - - - 0.3221 - 1.639 0.285 - 41.7 1 2 0 0.0008 23 0 0 0 5.35E+06 3.11E+06 - - - 2.8763 0.999 221125_WJC_METTL3_EV_vs_WT_F06.19872.19872.4 0.00262 Oct-66 R.DILQDYTHEFHK[136.11].T "sp|O95249|GOSR1_HUMAN,tr|B4DQA8|B4DQA8_HUMAN,tr|E9PCW1|E9PCW1_HUMAN,tr|K7EJC8|K7EJC8_HUMAN,tr|G5E9T8|G5E9T8_HUMAN" 5 1552.7402 1.59 87653 19872 4 1552.737817 389.1923 Golgi SNAP receptor complex member 1 OS=Homo sapiens OX=9606 GN=GOSR1 PE=1 SV=1 5.21 3144 - 269025 - - - -1.507 - 1.754 0.302 - 57.6 1 2 0 -0.0023 12 0 0 0 6.71E+06 4.21E+06 - - - 2.0666 1 221125_WJC_METTL3_EV_vs_WT_F06.19878.19878.3 9.02E-06 18/80 K.AGDTVSYVIC[160.03]QDGSNLTASQR[166.11].A "sp|P09884|DPOLA_HUMAN,tr|A6NMQ1|A6NMQ1_HUMAN" 2 2251.0414 0.18 87657 19878 3 2251.043566 751.3544 DNA polymerase alpha catalytic subunit OS=Homo sapiens OX=9606 GN=POLA1 PE=1 SV=2 4.21 3144.8 - 814830 - - - 0.9422 - 3.522 0.525 - 341.3 1 2 0 0.0021 21 0 0 0 2.32E+06 1.26E+07 - - - 7.4111 0.9928 221125_WJC_METTL3_EV_vs_WT_F06.19879.19879.3 2.15E-06 18/40 L.FDHIKLPQASK.S "sp|Q9NYF8|BCLF1_HUMAN,tr|E9PKI6|E9PKI6_HUMAN,tr|A0A1W2PQ43|A0A1W2PQ43_HUMAN,tr|E9PK91|E9PK91_HUMAN,tr|E9PJA7|E9PJA7_HUMAN,tr|E9PK09|E9PK09_HUMAN,tr|E9PQN2|E9PQN2_HUMAN" 7 1282.7034 2.17 87658 19879 3 1282.705148 428.5751 Bcl-2-associated transcription factor 1 OS=Homo sapiens OX=9606 GN=BCLAF1 PE=1 SV=2 8.6 3144.9 - 609356 - - - 1.3854 - 3.109 0.565 - 402.7 1 1 1 0.0018 11 0 0 0 1.06E+08 4.88E+07 - - - 8.0611 0.9991 221125_WJC_METTL3_EV_vs_WT_F06.19880.19880.3 0.000144 Nov-40 K.LK[136.11]VPEWVDTVK[136.11].L "sp|P39019|RS19_HUMAN,tr|M0R140|M0R140_HUMAN,tr|M0R2L9|M0R2L9_HUMAN,tr|M0QYF7|M0QYF7_HUMAN" 4 1328.7675 1.13 87659 19880 3 1328.767857 443.9298 40S ribosomal protein S19 OS=Homo sapiens OX=9606 GN=RPS19 PE=1 SV=2 6.07 3145 - 430431 - - - 0.2777 - 1.98 0.37 - 172.6 1 2 1 0.0004 11 0 0 0 3.28E+07 2.89E+07 - - - 4.6056 0.9999 221125_WJC_METTL3_EV_vs_WT_F06.19881.19881.3 1.11E-06 Nov-48 R.NYDVMK[136.11]DFEEMR[166.11]K[136.11].A sp|P09669|COX6C_HUMAN 1 1729.8014 0.97 87660 19881 3 1729.799655 577.6077 Cytochrome c oxidase subunit 6C OS=Homo sapiens OX=9606 GN=COX6C PE=1 SV=2 4.78 3145.2 - 412948 - - - -1.0071 - 2.506 0.54 - 118.5 1 2 1 -0.0017 13 0 0 0 5.98E+06 6.19E+06 - - - 7.0508 1 221125_WJC_METTL3_EV_vs_WT_F06.19883.19883.2 2.39E-09 14/38 R.FSGVPDRFSGSGSGTDFTLK.L "sp|A2NJV5|KV229_HUMAN,sp|A0A075B6S2|KVD29_HUMAN,sp|A0A0A0MRZ7|KVD26_HUMAN" 3 2060.9803 999 87662 19883 2 2060.982647 1031.4974 Immunoglobulin kappa variable 2-29 OS=Homo sapiens OX=9606 GN=IGKV2-29 PE=3 SV=2 5.96 3145.4 - 240556 - - - 1.1223 - 2.892 0.651 - 252.4 1 2 1 0.0023 20 0 0 0 4.93E+06 0.00E+00 - - - 6.4594 0.9999 221125_WJC_METTL3_EV_vs_WT_F06.19887.19887.3 1.09E-05 14/84 K.AASADSTTEGTPADGFTVLSTK.S sp|O75367|H2AY_HUMAN 1 2126.0015 1.35 87664 19887 3 2126.007331 709.6745 Core histone macro-H2A.1 OS=Homo sapiens OX=9606 GN=MACROH2A1 PE=1 SV=4 4.03 3146 - 726447 - - - 2.7319 - 2.896 0.497 - 262.5 1 2 0 0.0058 22 0 0 0 9.80E+06 7.28E+06 - - - 6.6004 1 221125_WJC_METTL3_EV_vs_WT_F06.19888.19888.3 1.10E-09 21/80 R.SSTFNSQEPHNILPLASSQIR.F "sp|Q8WTW3|COG1_HUMAN,tr|J3KSY3|J3KSY3_HUMAN,tr|E9PBL8|E9PBL8_HUMAN,tr|A0A087WVI0|A0A087WVI0_HUMAN,tr|J3QLT5|J3QLT5_HUMAN,tr|J3QKY9|J3QKY9_HUMAN" 6 2325.1713 1.36 87665 19888 3 2325.176752 776.0644 Conserved oligomeric Golgi complex subunit 1 OS=Homo sapiens OX=9606 GN=COG1 PE=1 SV=1 6.47 3146.1 - 1.05E+06 - - - 2.3349 - 3.588 0.603 - 349 1 2 0 0.0054 21 0 0 0 5.00E+07 3.69E+07 - - - 8.3243 0.9999 221125_WJC_METTL3_EV_vs_WT_F06.19889.19889.3 2.53E-07 16/80 R.SSTFNSQEPHNILPLASSQIR[166.11].F "sp|Q8WTW3|COG1_HUMAN,tr|J3KSY3|J3KSY3_HUMAN,tr|E9PBL8|E9PBL8_HUMAN,tr|A0A087WVI0|A0A087WVI0_HUMAN,tr|J3QLT5|J3QLT5_HUMAN,tr|J3QKY9|J3QKY9_HUMAN" 6 2335.1796 1.36 87666 19889 3 2335.185252 779.4005 Conserved oligomeric Golgi complex subunit 1 OS=Homo sapiens OX=9606 GN=COG1 PE=1 SV=1 6.47 3146.2 - 785943 - - - 2.4234 - 2.941 0.521 - 164.9 1 2 0 0.0057 21 0 0 0 5.00E+07 3.69E+07 - - - 6.9333 0.9998 221125_WJC_METTL3_EV_vs_WT_F06.19890.19890.4 1.32E-05 18/120 K.K[136.11]TPLSTGGTLAFVSPSLAVHK[136.11].S sp|Q86YP4|P66A_HUMAN 1 2126.207 1.53 87667 19890 4 2126.211685 532.559 Transcriptional repressor p66-alpha OS=Homo sapiens OX=9606 GN=GATAD2A PE=1 SV=1 10 3146.4 - 748895 - - - 2.1846 - 2.635 0.418 - 106.2 1 2 0 0.0046 21 0 0 0 2.08E+07 1.36E+07 - - - 3.1833 0.999 221125_WJC_METTL3_EV_vs_WT_F06.19891.19891.3 6.17E-05 14/72 K.INVPELPTPDEDNKLEVQK.V sp|O43264|ZW10_HUMAN 1 2177.1216 1.2 87668 19891 3 2177.128577 726.7145 Centromere\kinetochore protein zw10 homolog OS=Homo sapiens OX=9606 GN=ZW10 PE=1 SV=3 4.18 3146.5 - 605656 - - - 3.2143 - 2.533 0.46 - 119.7 1 2 1 0.007 19 0 0 0 1.90E+07 1.58E+07 - - - 5.95 0.9987 221125_WJC_METTL3_EV_vs_WT_F06.19897.19897.3 5.04E-05 Dec-48 R.SIFDHIK[136.11]LPQASK[136.11].S "sp|Q9NYF8|BCLF1_HUMAN,tr|E9PKI6|E9PKI6_HUMAN,tr|A0A1W2PQ43|A0A1W2PQ43_HUMAN,tr|E9PK91|E9PK91_HUMAN,tr|E9PJA7|E9PJA7_HUMAN,tr|E9PK09|E9PK09_HUMAN,tr|E9PQN2|E9PQN2_HUMAN" 7 1498.8479 2.11 87672 19897 3 1498.851229 500.6232 Bcl-2-associated transcription factor 1 OS=Homo sapiens OX=9606 GN=BCLAF1 PE=1 SV=2 8.33 3147.1 - 3.50E+06 - - - 2.2451 - 1.841 0.43 - 120.3 1 2 1 0.0034 13 0 0 0 1.03E+09 4.89E+08 - - - 4.9879 1 221125_WJC_METTL3_EV_vs_WT_F06.19898.19898.4 1.76E-06 24/162 R.TGTELVLLTAAPPPPPRPGPC[160.03]AYAAHGR.G "sp|Q96B36|AKTS1_HUMAN,tr|H9KV91|H9KV91_HUMAN" 2 2866.4912 2.54 87673 19898 4 2866.49479 717.6301 Proline-rich AKT1 substrate 1 OS=Homo sapiens OX=9606 GN=AKT1S1 PE=1 SV=1 7.92 3147.2 - 1.08E+06 - - - 1.2461 - 3.757 0.513 - 321.6 1 2 0 0.0036 28 0 0 0 3.16E+07 1.24E+07 - - - 4.1011 0.9999 221125_WJC_METTL3_EV_vs_WT_F06.19900.19900.4 1.26E-05 15/162 R.TGTELVLLTAAPPPPPR[166.11]PGPC[160.03]AYAAHGR[166.11].G "sp|Q96B36|AKTS1_HUMAN,tr|H9KV91|H9KV91_HUMAN" 2 2886.5078 2.44 87675 19900 4 2886.507616 722.6342 Proline-rich AKT1 substrate 1 OS=Homo sapiens OX=9606 GN=AKT1S1 PE=1 SV=1 7.92 3147.5 - 604719 - - - -0.0492 - 3.353 0.463 - 87.6 1 2 0 -0.0001 28 0 0 0 3.04E+07 1.24E+07 - - - 3.6315 1 221125_WJC_METTL3_EV_vs_WT_F06.19902.19902.3 1.42E-10 20/100 R.KYGGPPPDSVYSGQQPSVGTEIFVGK.L "sp|O60506|HNRPQ_HUMAN,tr|A0A7I2YQN2|A0A7I2YQN2_HUMAN,tr|A0A7I2V5Q6|A0A7I2V5Q6_HUMAN,tr|A0A7I2V4Z0|A0A7I2V4Z0_HUMAN,tr|B7Z645|B7Z645_HUMAN,tr|A0A7I2V2F2|A0A7I2V2F2_HUMAN,tr|F6UXX1|F6UXX1_HUMAN,tr|A0A7I2V309|A0A7I2V309_HUMAN" 8 2693.3337 1.26 87677 19902 3 2693.338633 898.7852 Heterogeneous nuclear ribonucleoprotein Q OS=Homo sapiens OX=9606 GN=SYNCRIP PE=1 SV=2 6.07 3147.8 - 537989 - - - 1.8327 - 4.022 0.642 - 228.5 1 2 0 0.0049 26 0 0 0 1.37E+08 1.09E+08 - - - 8.8983 1 221125_WJC_METTL3_EV_vs_WT_F06.19904.19904.2 2.25E-12 Nov-42 K.AASADSTTEGTPADGFTVLSTK.S sp|O75367|H2AY_HUMAN 1 2126.0015 1.06 87679 19904 2 2126.006301 1064.008 Core histone macro-H2A.1 OS=Homo sapiens OX=9606 GN=MACROH2A1 PE=1 SV=4 4.03 3148 - 201390 - - - 2.2474 - 2.823 0.738 - 200.4 1 2 0 0.0048 22 0 0 0 4.13E+06 3.88E+06 - - - 7.0418 1 221125_WJC_METTL3_EV_vs_WT_F06.19909.19909.3 1.11E-07 32/108 K.IQIASESSGIPERPC[160.03]VLTGTPESIEQAK.R sp|Q96I24|FUBP3_HUMAN 1 2996.5125 2.04 87682 19909 3 2996.511494 999.8448 Far upstream element-binding protein 3 OS=Homo sapiens OX=9606 GN=FUBP3 PE=1 SV=2 4.49 3148.7 - 1.82E+06 - - - -0.3244 - 4.001 0.567 - 667.7 1 2 0 -0.001 28 0 0 0 1.99E+09 9.73E+08 - - - 8.0512 1 221125_WJC_METTL3_EV_vs_WT_F06.19910.19910.3 1.23E-08 25/108 K.IQIASESSGIPER[166.11]PC[160.03]VLTGTPESIEQAK[136.11].R sp|Q96I24|FUBP3_HUMAN 1 3014.5349 2.04 87683 19910 3 3014.532171 1005.8523 Far upstream element-binding protein 3 OS=Homo sapiens OX=9606 GN=FUBP3 PE=1 SV=2 4.49 3148.8 - 1.12E+06 - - - -0.9172 - 3.633 0.605 - 293.1 1 2 0 -0.0028 28 0 0 0 1.99E+09 9.73E+08 - - - 8.2523 1 221125_WJC_METTL3_EV_vs_WT_F06.19911.19911.3 4.28E-12 18/68 K.KEDLISAFGTDDQTEIC[160.03]K.Q "sp|Q9Y3A5|SBDS_HUMAN,tr|A0A087X020|A0A087X020_HUMAN" 2 2068.9623 1.46 87684 19911 3 2068.963236 690.6614 Ribosome maturation protein SBDS OS=Homo sapiens OX=9606 GN=SBDS PE=1 SV=4 4.11 3148.9 - 1.03E+06 - - - 0.4519 - 3.682 0.672 - 401.1 1 2 0 0.0009 18 0 0 0 3.37E+07 2.30E+07 - - - 9.2776 1 221125_WJC_METTL3_EV_vs_WT_F06.19912.19912.3 0.000539 16/84 R.GTAITHALTSASTLC[160.03]QVEPVGR.W "sp|Q99543|DNJC2_HUMAN,tr|F2Z3H0|F2Z3H0_HUMAN,tr|F2Z3N9|F2Z3N9_HUMAN" 3 2268.1532 0.79 87685 19912 3 2268.14985 757.0584 DnaJ homolog subfamily C member 2 OS=Homo sapiens OX=9606 GN=DNAJC2 PE=1 SV=4 6.74 3149 - 658708 - - - -1.4902 - 3.188 0.464 - 230.3 1 2 0 -0.0034 22 0 0 0 7.17E+06 9.08E+06 - - - 6.4609 0.9989 221125_WJC_METTL3_EV_vs_WT_F06.19913.19913.3 8.49E-05 14/68 R.LGSSSLTNIPEEVREHVK.L "sp|Q6P3W7|SCYL2_HUMAN,tr|F8VSC5|F8VSC5_HUMAN,tr|A0A0U1RQQ9|A0A0U1RQQ9_HUMAN" 3 1994.0433 4.83 87686 19913 3 1994.048723 665.6884 SCY1-like protein 2 OS=Homo sapiens OX=9606 GN=SCYL2 PE=1 SV=1 5.5 3149.2 - 613654 - - - 2.7351 - 2.748 0.399 - 161.9 1 2 1 0.0055 18 0 0 0 7.11E+06 1.47E+06 - - - 5.5041 0.9963 221125_WJC_METTL3_EV_vs_WT_F06.19918.19918.4 1.77E-05 23/162 K.IQIASESSGIPERPC[160.03]VLTGTPESIEQAK.R sp|Q96I24|FUBP3_HUMAN 1 2996.5125 1.85 87689 19918 4 2996.517551 750.1354 Far upstream element-binding protein 3 OS=Homo sapiens OX=9606 GN=FUBP3 PE=1 SV=2 4.49 3149.8 - 1.28E+06 - - - 1.697 - 3.587 0.231 - 274.4 1 2 0 0.0051 28 0 0 0 5.05E+08 2.73E+08 - - - 1.6318 1 221125_WJC_METTL3_EV_vs_WT_F06.19919.19919.3 1.01E-11 25/100 R.K[136.11]YGGPPPDSVYSGQQPSVGTEIFVGK[136.11].L "sp|O60506|HNRPQ_HUMAN,tr|A0A7I2YQN2|A0A7I2YQN2_HUMAN,tr|A0A7I2V5Q6|A0A7I2V5Q6_HUMAN,tr|A0A7I2V4Z0|A0A7I2V4Z0_HUMAN,tr|B7Z645|B7Z645_HUMAN,tr|A0A7I2V2F2|A0A7I2V2F2_HUMAN,tr|F6UXX1|F6UXX1_HUMAN,tr|A0A7I2V309|A0A7I2V309_HUMAN" 8 2709.3621 1.25 87690 19919 3 2709.363246 904.128 Heterogeneous nuclear ribonucleoprotein Q OS=Homo sapiens OX=9606 GN=SYNCRIP PE=1 SV=2 6.07 3149.9 - 1.31E+06 - - - 0.4241 - 4.281 0.659 - 537 1 2 0 0.0011 26 0 0 0 1.18E+08 9.43E+07 - - - 9.2324 0.9702 221125_WJC_METTL3_EV_vs_WT_F06.19924.19924.4 1.04E-05 Nov-78 R.DHQLLEPIRDFEAR.K sp|Q14134|TRI29_HUMAN 1 1737.8798 81.26 87695 19924 4 1737.894086 435.4772 Tripartite motif-containing protein 29 OS=Homo sapiens OX=9606 GN=TRIM29 PE=1 SV=2 4.75 3150.6 - 450073 - - - 8.2019 - 2.107 0.425 - 100.3 1 2 1 0.0143 14 0 0 0 9.43E+06 1.16E+05 - - - 3.1925 0.9999 221125_WJC_METTL3_EV_vs_WT_F06.19930.19930.4 1.74E-05 17/162 K.IQIASESSGIPER[166.11]PC[160.03]VLTGTPESIEQAK[136.11].R sp|Q96I24|FUBP3_HUMAN 1 3014.5349 1.85 87699 19930 4 3014.533533 754.641 Far upstream element-binding protein 3 OS=Homo sapiens OX=9606 GN=FUBP3 PE=1 SV=2 4.49 3151.2 - 2.81E+06 - - - -0.4654 - 2.669 0.424 - 141.2 1 2 0 -0.0014 28 0 0 0 5.03E+08 2.72E+08 - - - 3.2209 0.9997 221125_WJC_METTL3_EV_vs_WT_F06.19932.19932.3 8.64E-09 23/72 R.SIQETLGESGSLLPNKLNK.L sp|Q96BP2|CHCH1_HUMAN 1 2027.0899 1.4 87701 19932 3 2027.097479 676.7039 Coiled-coil-helix-coiled-coil-helix domain-containing protein 1 OS=Homo sapiens OX=9606 GN=CHCHD1 PE=1 SV=1 5.86 3151.4 - 1.18E+06 - - - 3.7463 - 3.176 0.6 - 374.5 1 2 1 0.0076 19 0 0 0 4.28E+08 3.06E+08 - - - 8.0664 1 221125_WJC_METTL3_EV_vs_WT_F06.19937.19937.3 1.55E-11 27/84 K.EAQDAPGLDPQGAADC[160.03]AQGVLR.Q "sp|P39880|CUX1_HUMAN,tr|A0A2R8Y852|A0A2R8Y852_HUMAN,tr|A0A2R8YDI1|A0A2R8YDI1_HUMAN" 3 2238.0335 1.9 87704 19937 3 2238.035076 747.0184 Homeobox protein cut-like 1 OS=Homo sapiens OX=9606 GN=CUX1 PE=1 SV=3 3.84 3152.1 - 2.19E+06 - - - 0.7002 - 4.068 0.657 - 719 1 2 0 0.0016 22 0 0 0 8.79E+07 4.62E+07 - - - 9.1911 1 221125_WJC_METTL3_EV_vs_WT_F06.19943.19943.4 5.53E-06 12/108 R.GLLQDDAHPTLVTYADHSK[136.11].L "sp|Q86U44|MTA70_HUMAN,tr|F5H6D8|F5H6D8_HUMAN,tr|H0YFV6|H0YFV6_HUMAN,tr|B4DTN4|B4DTN4_HUMAN" 4 2088.0367 0.05 87708 19943 4 2088.037217 523.0165 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 5.13 3152.8 - 2.44E+06 - - - 0.2318 - 2.688 0.49 - 133.3 1 2 0 0.0005 19 0 0 0 5.38E+06 9.88E+07 - - - 3.8253 0.9999 221125_WJC_METTL3_EV_vs_WT_F06.19945.19945.4 2.98E-06 22/108 R.DK[136.11]VAGHSLGYGFVNYVTAK[136.11].D "sp|Q15717|ELAV1_HUMAN,tr|M0QZR9|M0QZR9_HUMAN" 2 2041.0604 1.36 87710 19945 4 2041.058185 511.2724 ELAV-like protein 1 OS=Homo sapiens OX=9606 GN=ELAVL1 PE=1 SV=2 8.44 3153.1 - 1.11E+06 - - - -1.0735 - 3.738 0.503 - 331.7 1 2 1 -0.0022 19 0 0 0 1.57E+08 1.15E+08 - - - 4.0495 1 221125_WJC_METTL3_EV_vs_WT_F06.19950.19950.3 1.48E-09 24/72 K.QGAPTSFLPPEASQLK[136.11]PDR[166.11].Q "sp|Q9BUJ2|HNRL1_HUMAN,tr|M0R0K8|M0R0K8_HUMAN,tr|M0QYZ0|M0QYZ0_HUMAN,tr|A0A0A0MRA5|A0A0A0MRA5_HUMAN,tr|M0QZV6|M0QZV6_HUMAN,tr|B7Z4B8|B7Z4B8_HUMAN,tr|M0QYI8|M0QYI8_HUMAN,tr|M0R203|M0R203_HUMAN" 8 2056.0708 4.38 87713 19950 3 2056.071596 686.3642 Heterogeneous nuclear ribonucleoprotein U-like protein 1 OS=Homo sapiens OX=9606 GN=HNRNPUL1 PE=1 SV=2 6.07 3153.7 - 1.31E+06 - - - 0.3755 - 4.039 0.594 - 584.4 1 2 0 0.0008 19 0 0 0 1.94E+08 4.43E+07 - - - 8.592 0.9881 221125_WJC_METTL3_EV_vs_WT_F06.19951.19951.3 3.61E-05 17/40 L.FDHIK[136.11]LPQASK[136.11].S "sp|Q9NYF8|BCLF1_HUMAN,tr|E9PKI6|E9PKI6_HUMAN,tr|A0A1W2PQ43|A0A1W2PQ43_HUMAN,tr|E9PK91|E9PK91_HUMAN,tr|E9PJA7|E9PJA7_HUMAN,tr|E9PK09|E9PK09_HUMAN,tr|E9PQN2|E9PQN2_HUMAN" 7 1298.7318 2.17 87714 19951 3 1298.731038 433.9179 Bcl-2-associated transcription factor 1 OS=Homo sapiens OX=9606 GN=BCLAF1 PE=1 SV=2 8.6 3153.9 - 1.02E+06 - - - -0.5644 - 2.738 0.48 - 371.7 1 1 1 -0.0007 11 0 0 0 1.06E+08 4.88E+07 - - - 6.7527 1 221125_WJC_METTL3_EV_vs_WT_F06.19955.19955.3 1.71E-13 21/96 K.LVQDVANNTNEEAGDGTTTATVLAR[166.11].S "sp|P10809|CH60_HUMAN,tr|C9JL25|C9JL25_HUMAN,tr|A0A7I2V2X6|A0A7I2V2X6_HUMAN,tr|A0A7I2YQK6|A0A7I2YQK6_HUMAN,tr|A0A7I2V599|A0A7I2V599_HUMAN,tr|E7EXB4|E7EXB4_HUMAN,tr|A0A7I2YQ71|A0A7I2YQ71_HUMAN,tr|E7ESH4|E7ESH4_HUMAN,tr|A0A7I2V5M1|A0A7I2V5M1_HUMAN,tr|A0A7I2V5K3|A0A7I2V5K3_HUMAN,tr|A0A7I2V369|A0A7I2V369_HUMAN" 11 2569.2495 1.56 87716 19955 3 2569.250689 857.4238 "60 kDa heat shock protein, mitochondrial OS=Homo sapiens OX=9606 GN=HSPD1 PE=1 SV=2" 3.92 3154.4 - 514019 - - - 0.4538 - 3.905 0.686 - 616.7 1 2 0 0.0012 25 0 0 0 3.01E+07 1.93E+07 - - - 9.322 1 221125_WJC_METTL3_EV_vs_WT_F06.19958.19958.2 8.29E-16 16/38 R.FSSC[160.03]GGGGGSFGAGGGFGSR.S sp|P04264|K2C1_HUMAN 1 1764.7274 999 87719 19958 2 1764.726756 883.371 "Keratin, type II cytoskeletal 1 OS=Homo sapiens OX=9606 GN=KRT1 PE=1 SV=6" 8.25 3154.8 - 442098 - - - -0.3825 - 3.625 0.796 - 792.6 1 2 0 -0.0007 20 0 0 0 2.90E+07 0.00E+00 - - - 8.0863 0.9993 221125_WJC_METTL3_EV_vs_WT_F06.19962.19962.3 1.25E-05 15/72 R.SIQETLGESGSLLPNK[136.11]LNK[136.11].L sp|Q96BP2|CHCH1_HUMAN 1 2043.1183 1.4 87721 19962 3 2043.124635 682.0467 Coiled-coil-helix-coiled-coil-helix domain-containing protein 1 OS=Homo sapiens OX=9606 GN=CHCHD1 PE=1 SV=1 5.86 3155.2 - 3.66E+06 - - - 3.108 - 2.649 0.485 - 123.3 1 2 1 0.0063 19 0 0 0 4.28E+08 3.06E+08 - - - 6.3389 1 221125_WJC_METTL3_EV_vs_WT_F06.19965.19965.3 7.37E-12 21/60 K.RGFGFVTFDDHDPVDK.L "sp|P22626|ROA2_HUMAN,tr|A0A7I2V4N0|A0A7I2V4N0_HUMAN,tr|A0A024RA28|A0A024RA28_HUMAN,tr|A0A7I2V4N1|A0A7I2V4N1_HUMAN,tr|A0A7I2V4I6|A0A7I2V4I6_HUMAN,tr|A0A087WUI2|A0A087WUI2_HUMAN,tr|A0A7I2V4S4|A0A7I2V4S4_HUMAN,tr|A0A7I2V323|A0A7I2V323_HUMAN,tr|A0A7I2V3P1|A0A7I2V3P1_HUMAN,tr|A0A7I2V3P7|A0A7I2V3P7_HUMAN" 10 1850.8588 163.49 87724 19965 3 1850.86024 617.9602 Heterogeneous nuclear ribonucleoproteins A2\B1 OS=Homo sapiens OX=9606 GN=HNRNPA2B1 PE=1 SV=2 4.56 3155.6 - 536399 - - - 0.798 - 3.922 0.657 - 577.9 1 2 0 0.0015 16 0 0 0 6.93E+07 4.24E+05 - - - 9.371 1 221125_WJC_METTL3_EV_vs_WT_F06.19969.19969.2 1.29E-08 23/34 R.NLNHSLPSDFTFQNMNSK.R sp|Q15208|STK38_HUMAN 1 2092.9636 5.5 87726 19969 2 2092.962757 1047.4891 Serine\threonine-protein kinase 38 OS=Homo sapiens OX=9606 GN=STK38 PE=1 SV=1 6.74 3156 - 1.74E+06 - - - -0.4209 - 4.287 0.65 - 1686.6 1 2 0 -0.0009 18 0 0 0 5.86E+07 1.07E+07 - - - 7.4203 1 221125_WJC_METTL3_EV_vs_WT_F06.19970.19970.2 2.05E-11 14/34 R.NLNHSLPSDFTFQNMNSK[136.11].R sp|Q15208|STK38_HUMAN 1 2100.9778 5.5 87727 19970 2 2101.976561 1051.4962 Serine\threonine-protein kinase 38 OS=Homo sapiens OX=9606 GN=STK38 PE=1 SV=1 6.74 3156.1 - 455718 - - - 475.361 - 3.668 0.683 - 472.7 1 2 0 0.9987 18 0 0 0 5.86E+07 1.07E+07 - - - 6.9673 0.9995 221125_WJC_METTL3_EV_vs_WT_F06.19973.19973.4 0.00257 13/90 R.NEDISSHLHQIPSLLK.L "sp|Q5VWN6|TASO2_HUMAN,tr|A0A2R8YH03|A0A2R8YH03_HUMAN" 2 1829.9636 1.88 87730 19973 4 1829.962307 458.4982 Protein TASOR 2 OS=Homo sapiens OX=9606 GN=TASOR2 PE=1 SV=1 5.99 3156.4 - 737418 - - - -0.6858 - 1.882 0.336 - 115.5 1 2 0 -0.0013 16 0 0 0 3.23E+07 1.73E+07 - - - 2.3729 0.9999 221125_WJC_METTL3_EV_vs_WT_F06.19980.19980.4 6.06E-08 15/108 R.DKVAGHSLGYGFVNYVTAK.D "sp|Q15717|ELAV1_HUMAN,tr|M0QZR9|M0QZR9_HUMAN" 2 2025.032 1.35 87734 19980 4 2025.033912 507.2653 ELAV-like protein 1 OS=Homo sapiens OX=9606 GN=ELAVL1 PE=1 SV=2 8.44 3157.2 - 6.56E+06 - - - 0.956 - 3.283 0.57 - 181.7 1 2 1 0.0019 19 0 0 0 1.55E+08 1.15E+08 - - - 4.5889 1 221125_WJC_METTL3_EV_vs_WT_F06.19982.19982.4 1.48E-10 20/90 K.RGFGFVTFDDHDPVDK.L "sp|P22626|ROA2_HUMAN,tr|A0A7I2V4N0|A0A7I2V4N0_HUMAN,tr|A0A024RA28|A0A024RA28_HUMAN,tr|A0A7I2V4N1|A0A7I2V4N1_HUMAN,tr|A0A7I2V4I6|A0A7I2V4I6_HUMAN,tr|A0A087WUI2|A0A087WUI2_HUMAN,tr|A0A7I2V4S4|A0A7I2V4S4_HUMAN,tr|A0A7I2V323|A0A7I2V323_HUMAN,tr|A0A7I2V3P1|A0A7I2V3P1_HUMAN,tr|A0A7I2V3P7|A0A7I2V3P7_HUMAN" 10 1850.8588 1.11 87736 19982 4 1850.855688 463.722 Heterogeneous nuclear ribonucleoproteins A2\B1 OS=Homo sapiens OX=9606 GN=HNRNPA2B1 PE=1 SV=2 4.56 3157.4 - 927411 - - - -1.6614 - 3.015 0.618 - 347.6 1 2 0 -0.0031 16 0 0 0 5.60E+07 5.04E+07 - - - 4.993 0.9999 221125_WJC_METTL3_EV_vs_WT_F06.19991.19991.3 4.61E-07 Dec-76 K.DPEPPEK[136.11]EFTPYDYSQSDFK[136.11].A sp|Q01780|EXOSX_HUMAN 1 2434.0824 0.21 87743 19991 3 2434.079009 812.3681 Exosome component 10 OS=Homo sapiens OX=9606 GN=EXOSC10 PE=1 SV=2 4.02 3158.6 - 610998 - - - -1.3738 - 2.888 0.556 - 168.8 1 2 1 -0.0033 20 0 0 0 5.86E+06 2.81E+07 - - - 7.3109 0.9999 221125_WJC_METTL3_EV_vs_WT_F06.19997.19997.4 7.26E-08 19/108 K.FSQELLSNGELNHLPLKER.M "sp|P17480|UBF1_HUMAN,tr|E9PKP7|E9PKP7_HUMAN,tr|E9PLT2|E9PLT2_HUMAN" 3 2223.1648 1.59 87746 19997 4 2223.167575 556.7985 Nucleolar transcription factor 1 OS=Homo sapiens OX=9606 GN=UBTF PE=1 SV=1 5.5 3159.3 - 940256 - - - 1.2568 - 3.87 0.553 - 241.4 1 2 1 0.0028 19 0 0 0 2.52E+07 1.58E+07 - - - 4.4963 1 221125_WJC_METTL3_EV_vs_WT_F06.20000.20000.3 1.02E-09 25/92 K.EGTLTQVPLAPPPPGAPPSPAPAR.F sp|P48634|PRC2A_HUMAN 1 2317.243 1.79 87749 20000 3 2317.242313 773.4216 Protein PRRC2A OS=Homo sapiens OX=9606 GN=PRRC2A PE=1 SV=3 6.1 3159.7 - 867184 - - - -0.3099 - 3.747 0.578 - 575.3 1 2 0 -0.0007 24 0 0 0 2.61E+08 1.46E+08 - - - 8.052 0.9996 221125_WJC_METTL3_EV_vs_WT_F06.20004.20004.4 1.61E-05 18/108 K.FSQELLSNGELNHLPLK[136.11]ER[166.11].M "sp|P17480|UBF1_HUMAN,tr|E9PKP7|E9PKP7_HUMAN,tr|E9PLT2|E9PLT2_HUMAN" 3 2241.1873 1.59 87751 20004 4 2241.187506 561.3041 Nucleolar transcription factor 1 OS=Homo sapiens OX=9606 GN=UBTF PE=1 SV=1 5.5 3160.2 - 1.01E+06 - - - 0.1138 - 2.354 0.424 - 189.6 1 2 1 0.0003 19 0 0 0 2.52E+07 1.58E+07 - - - 3.206 1 221125_WJC_METTL3_EV_vs_WT_F06.20012.20012.4 3.73E-07 19/84 K.LSTDDLNSLIAHAHR.R "sp|Q16891|MIC60_HUMAN,tr|B9A067|B9A067_HUMAN,tr|C9J406|C9J406_HUMAN,tr|H7C463|H7C463_HUMAN" 4 1661.8485 1.55 87756 20012 4 1661.847336 416.4694 MICOS complex subunit MIC60 OS=Homo sapiens OX=9606 GN=IMMT PE=1 SV=1 5.98 3161.3 - 977087 - - - -0.7197 - 3.549 0.521 - 460.2 1 2 0 -0.0012 15 0 0 0 4.71E+08 3.05E+08 - - - 4.2137 0.9999 221125_WJC_METTL3_EV_vs_WT_F06.20013.20013.4 5.47E-07 18/84 K.LSTDDLNSLIAHAHR[166.11].R "sp|Q16891|MIC60_HUMAN,tr|B9A067|B9A067_HUMAN,tr|C9J406|C9J406_HUMAN,tr|H7C463|H7C463_HUMAN" 4 1671.8568 1.55 87757 20013 4 1671.854296 418.9715 MICOS complex subunit MIC60 OS=Homo sapiens OX=9606 GN=IMMT PE=1 SV=1 5.98 3161.5 - 918826 - - - -1.4989 - 3.627 0.432 - 429.7 1 2 0 -0.0025 15 0 0 0 4.71E+08 3.05E+08 - - - 3.4464 1 221125_WJC_METTL3_EV_vs_WT_F06.20020.20020.4 1.44E-05 17/90 K.R[166.11]GFGFVTFDDHDPVDK[136.11].L "sp|P22626|ROA2_HUMAN,tr|A0A7I2V4N0|A0A7I2V4N0_HUMAN,tr|A0A024RA28|A0A024RA28_HUMAN,tr|A0A7I2V4N1|A0A7I2V4N1_HUMAN,tr|A0A7I2V4I6|A0A7I2V4I6_HUMAN,tr|A0A087WUI2|A0A087WUI2_HUMAN,tr|A0A7I2V4S4|A0A7I2V4S4_HUMAN,tr|A0A7I2V323|A0A7I2V323_HUMAN,tr|A0A7I2V3P1|A0A7I2V3P1_HUMAN,tr|A0A7I2V3P7|A0A7I2V3P7_HUMAN" 10 1868.8812 1.13 87762 20020 4 1868.877644 468.2276 Heterogeneous nuclear ribonucleoproteins A2\B1 OS=Homo sapiens OX=9606 GN=HNRNPA2B1 PE=1 SV=2 4.56 3162.3 - 1.64E+06 - - - -1.9204 - 2.687 0.59 - 250.6 1 2 0 -0.0036 16 0 0 0 5.62E+07 4.97E+07 - - - 4.7085 1 221125_WJC_METTL3_EV_vs_WT_F06.20021.20021.3 1.77E-10 21/88 K.SADGEEAAAVPGPPPEPQVPQLR.A sp|Q8TAP8|PPR35_HUMAN 1 2311.1444 2.86 87763 20021 3 2311.144675 771.3888 Protein phosphatase 1 regulatory subunit 35 OS=Homo sapiens OX=9606 GN=PPP1R35 PE=1 SV=1 4 3162.4 - 1.33E+06 - - - 0.1017 - 3.887 0.608 - 383.2 1 2 0 0.0002 23 0 0 0 4.00E+07 1.40E+07 - - - 8.5035 1 221125_WJC_METTL3_EV_vs_WT_F06.20022.20022.3 4.86E-07 16/88 K.EIETYHNLLEGGQEDFESSGAGK.L "sp|P35527|K1C9_HUMAN,tr|K7EQQ3|K7EQQ3_HUMAN" 2 2509.1245 999 87764 20022 3 2509.123535 837.3821 "Keratin, type I cytoskeletal 9 OS=Homo sapiens OX=9606 GN=KRT9 PE=1 SV=3" 4.14 3162.6 - 973012 - - - -0.3814 - 3.516 0.622 - 338.2 1 2 0 -0.001 23 0 0 0 1.22E+07 0.00E+00 - - - 8.424 1 221125_WJC_METTL3_EV_vs_WT_F06.20027.20027.3 1.29E-07 20/56 K.LSTDDLNSLIAHAHR[166.11].R "sp|Q16891|MIC60_HUMAN,tr|B9A067|B9A067_HUMAN,tr|C9J406|C9J406_HUMAN,tr|H7C463|H7C463_HUMAN" 4 1671.8568 1.39 87767 20027 3 1671.855579 558.2929 MICOS complex subunit MIC60 OS=Homo sapiens OX=9606 GN=IMMT PE=1 SV=1 5.98 3163.2 - 1.52E+06 - - - -0.7315 - 3.447 0.579 - 719.2 1 2 0 -0.0012 15 0 0 0 2.38E+08 1.71E+08 - - - 8.224 1 221125_WJC_METTL3_EV_vs_WT_F06.20030.20030.3 7.41E-09 16/44 R.SHSAHFFEFLTK[136.11].E "sp|P30046|DOPD_HUMAN,sp|A6NHG4|DDTL_HUMAN,tr|J3KQ18|J3KQ18_HUMAN,tr|B5MC82|B5MC82_HUMAN" 4 1457.7183 1.1 87770 20030 3 1457.720353 486.9134 D-dopachrome decarboxylase OS=Homo sapiens OX=9606 GN=DDT PE=1 SV=3 6.66 3163.5 - 393387 - - - 1.4084 - 2.979 0.625 - 270.3 1 2 0 0.0021 12 0 0 0 2.01E+07 1.82E+07 - - - 8.5333 0.9523 221125_WJC_METTL3_EV_vs_WT_F06.20031.20031.3 0.187 Dec-44 S.IFDHIK[136.11]LPQASK[136.11].S "sp|Q9NYF8|BCLF1_HUMAN,tr|E9PKI6|E9PKI6_HUMAN,tr|A0A1W2PQ43|A0A1W2PQ43_HUMAN,tr|E9PK91|E9PK91_HUMAN,tr|E9PJA7|E9PJA7_HUMAN,tr|E9PK09|E9PK09_HUMAN,tr|E9PQN2|E9PQN2_HUMAN" 7 1411.8158 1.94 87771 20031 3 1411.814136 471.6126 Bcl-2-associated transcription factor 1 OS=Homo sapiens OX=9606 GN=BCLAF1 PE=1 SV=2 8.6 3163.7 - 259569 - - - -1.2034 - 2.282 0.397 - 133.2 1 1 1 -0.0017 12 0 0 0 2.28E+07 1.17E+07 - - - 5.2526 1 221125_WJC_METTL3_EV_vs_WT_F06.20035.20035.3 2.64E-08 19/56 K.LSTDDLNSLIAHAHR.R "sp|Q16891|MIC60_HUMAN,tr|B9A067|B9A067_HUMAN,tr|C9J406|C9J406_HUMAN,tr|H7C463|H7C463_HUMAN" 4 1661.8485 1.37 87773 20035 3 1661.84845 554.9568 MICOS complex subunit MIC60 OS=Homo sapiens OX=9606 GN=IMMT PE=1 SV=1 5.98 3164.1 - 2.99E+06 - - - -0.0493 - 3.275 0.578 - 545.8 1 2 0 -0.0001 15 0 0 0 2.38E+08 1.74E+08 - - - 8.0796 1 221125_WJC_METTL3_EV_vs_WT_F06.20036.20036.3 8.92E-10 27/92 K.EGTLTQVPLAPPPPGAPPSPAPAR[166.11].F sp|P48634|PRC2A_HUMAN 1 2327.2513 1.79 87774 20036 3 2327.251959 776.7577 Protein PRRC2A OS=Homo sapiens OX=9606 GN=PRRC2A PE=1 SV=3 6.1 3164.2 - 1.02E+06 - - - 0.2827 - 4.349 0.505 - 748 1 2 0 0.0007 24 0 0 0 2.62E+08 1.46E+08 - - - 7.5842 0.9996 221125_WJC_METTL3_EV_vs_WT_F06.20038.20038.4 0.00153 14/108 K.VHDSNIYIK[136.11]PFLSSAPEVR[166.11].L sp|Q9ULR3|PPM1H_HUMAN 1 2189.16 1.29 87776 20038 4 2189.167025 548.2973 Protein phosphatase 1H OS=Homo sapiens OX=9606 GN=PPM1H PE=1 SV=2 6.72 3164.5 - 364285 - - - 3.2209 - 2.544 0.413 - 134.7 1 2 0 0.0071 19 0 0 0 1.48E+06 1.14E+06 - - - 3.1347 0.9999 221125_WJC_METTL3_EV_vs_WT_F06.20041.20041.3 1.58E-05 13/48 R.SIFDHIKLPQASK.S "sp|Q9NYF8|BCLF1_HUMAN,tr|E9PKI6|E9PKI6_HUMAN,tr|A0A1W2PQ43|A0A1W2PQ43_HUMAN,tr|E9PK91|E9PK91_HUMAN,tr|E9PJA7|E9PJA7_HUMAN,tr|E9PK09|E9PK09_HUMAN,tr|E9PQN2|E9PQN2_HUMAN" 7 1482.8195 2.11 87778 20041 3 1482.8199 495.2804 Bcl-2-associated transcription factor 1 OS=Homo sapiens OX=9606 GN=BCLAF1 PE=1 SV=2 8.33 3164.9 - 1.87E+07 - - - 0.294 - 2.387 0.535 - 147.7 1 2 1 0.0004 13 0 0 0 1.02E+09 4.86E+08 - - - 6.8635 0.9998 221125_WJC_METTL3_EV_vs_WT_F06.20045.20045.2 0.000103 20-Nov K.WEGLVYAPPGK.E "sp|Q9Y2W1|TR150_HUMAN,tr|A0A3B3ITZ9|A0A3B3ITZ9_HUMAN" 2 1215.6288 3.93 87782 20045 2 1215.630315 608.8217 Thyroid hormone receptor-associated protein 3 OS=Homo sapiens OX=9606 GN=THRAP3 PE=1 SV=2 6 3165.2 - 717228 - - - 1.2389 - 2.027 0.518 - 321.3 1 2 0 0.0015 11 0 0 0 2.88E+07 7.32E+06 - - - 4.7779 1 221125_WJC_METTL3_EV_vs_WT_F06.20046.20046.3 3.76E-10 19/44 R.SHSAHFFEFLTK.E "sp|P30046|DOPD_HUMAN,sp|A6NHG4|DDTL_HUMAN,tr|J3KQ18|J3KQ18_HUMAN,tr|B5MC82|B5MC82_HUMAN" 4 1449.7041 1.1 87783 20046 3 1449.705521 484.242 D-dopachrome decarboxylase OS=Homo sapiens OX=9606 GN=DDT PE=1 SV=3 6.66 3165.4 - 401088 - - - 0.9802 - 3.889 0.603 - 458.1 1 2 0 0.0014 12 0 0 0 2.01E+07 1.82E+07 - - - 9.0271 1 221125_WJC_METTL3_EV_vs_WT_F06.20048.20048.2 4.15E-09 15/36 R.SIQETLGESGSLLPNKLNK.L sp|Q96BP2|CHCH1_HUMAN 1 2027.0899 2.06 87785 20048 2 2027.087808 1014.5522 Coiled-coil-helix-coiled-coil-helix domain-containing protein 1 OS=Homo sapiens OX=9606 GN=CHCHD1 PE=1 SV=1 5.86 3165.6 - 348941 - - - -1.0246 - 2.926 0.652 - 434.9 1 2 1 -0.0021 19 0 0 0 3.88E+06 1.88E+06 - - - 6.4956 0.9976 221125_WJC_METTL3_EV_vs_WT_F06.20056.20056.3 9.04E-07 14/84 K.GILGYTEHQVVSSDFNSDTHSS.T "sp|P04406|G3P_HUMAN,tr|E7EUT5|E7EUT5_HUMAN" 2 2379.0615 - 87791 20056 3 2379.057434 794.0278 Glyceraldehyde-3-phosphate dehydrogenase OS=Homo sapiens OX=9606 GN=GAPDH PE=1 SV=3 4.52 3166.5 - 698612 - - - -1.7082 - 2.68 0.589 - 207.6 1 1 0 -0.0041 22 0 0 0 - - - - - 7.4428 0.9237 221125_WJC_METTL3_EV_vs_WT_F06.20059.20059.2 0.829 14-Sep N.SLIAHAHR.R "sp|Q16891|MIC60_HUMAN,tr|B9A067|B9A067_HUMAN,tr|C9J406|C9J406_HUMAN,tr|H7C463|H7C463_HUMAN" 4 903.5039 1.33 87794 20059 2 903.502211 452.7592 MICOS complex subunit MIC60 OS=Homo sapiens OX=9606 GN=IMMT PE=1 SV=1 9.51 3166.9 - 526899 - - - -1.8517 - 1.68 0.282 - 344.6 1 1 0 -0.0017 8 0 0 0 1.62E+07 1.22E+07 - - - 2.688 0.9993 221125_WJC_METTL3_EV_vs_WT_F06.20072.20072.3 4.37E-07 21/96 R.NPGTTVSAASPFPQGSFSGTPGSVK.S sp|P55197|AF10_HUMAN 1 2377.155 145.45 87803 20072 3 2377.154151 793.3923 Protein AF-10 OS=Homo sapiens OX=9606 GN=MLLT10 PE=1 SV=2 8.75 3168.5 - 1.68E+06 - - - -0.3588 - 3.41 0.196 - 375.9 1 2 0 -0.0009 25 0 0 0 9.50E+09 6.53E+07 - - - 3.5472 1 221125_WJC_METTL3_EV_vs_WT_F06.20081.20081.3 2.09E-08 17/68 K.YVHYEIDAC[160.03]MDSEAPGSK[136.11].D "sp|Q86U44|MTA70_HUMAN,tr|H0YFV6|H0YFV6_HUMAN" 2 2078.8805 0.001 87810 20081 3 2078.877102 693.9674 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 4.31 3169.4 - 2.69E+06 - - - -1.6307 - 3.376 0.616 - 292.8 1 2 0 -0.0034 18 0 0 0 0.00E+00 1.71E+08 - - - 8.4365 1 221125_WJC_METTL3_EV_vs_WT_F06.20083.20083.3 4.32E-09 28/80 R.QVQSLTC[160.03]EVDALK[136.11]GTNESLER[166.11].Q "sp|P08670|VIME_HUMAN,tr|B0YJC5|B0YJC5_HUMAN,tr|B0YJC4|B0YJC4_HUMAN" 3 2394.1816 1.74 87812 20083 3 2394.178322 799.0678 Vimentin OS=Homo sapiens OX=9606 GN=VIM PE=1 SV=4 4.41 3169.6 - 1.85E+06 - - - -1.3583 - 4.614 0.63 - 874.5 1 2 1 -0.0033 21 0 0 0 9.86E+09 5.65E+09 - - - 9.2289 1 221125_WJC_METTL3_EV_vs_WT_F06.20084.20084.3 1.47E-10 23/80 K.FQYC[160.03]VAVGAQTFPSVSAPSK[136.11]K[136.11].V "sp|P55265|DSRAD_HUMAN,tr|A0A3B3IRQ9|A0A3B3IRQ9_HUMAN,tr|A0A3B3ISU1|A0A3B3ISU1_HUMAN,tr|A0A7P0Z4K3|A0A7P0Z4K3_HUMAN,tr|A0A3B3ISX1|A0A3B3ISX1_HUMAN,tr|A0A7P0Z4F9|A0A7P0Z4F9_HUMAN" 6 2287.1642 0.93 87813 20084 3 2287.157825 763.3953 Double-stranded RNA-specific adenosine deaminase OS=Homo sapiens OX=9606 GN=ADAR PE=1 SV=4 9.2 3169.8 - 875067 - - - -2.7825 - 3.633 0.645 - 473.6 1 2 0 -0.0064 21 0 0 0 1.11E+08 1.19E+08 - - - 8.8222 1 221125_WJC_METTL3_EV_vs_WT_F06.20085.20085.3 1.17E-08 16/64 R.DHAMVPLEEAAQEYQEK.L sp|P19474|RO52_HUMAN 1 1986.8993 3.58 87814 20085 3 1986.89625 663.307 E3 ubiquitin-protein ligase TRIM21 OS=Homo sapiens OX=9606 GN=TRIM21 PE=1 SV=1 4.25 3169.9 - 832435 - - - -1.5386 - 3.213 0.595 - 266.2 1 2 0 -0.0031 17 0 0 0 4.45E+07 1.24E+07 - - - 8.1215 0.9964 221125_WJC_METTL3_EV_vs_WT_F06.20086.20086.4 0.0482 Nov-66 K.KWNLDELPKFEK.N "sp|P17844|DDX5_HUMAN,tr|J3QR02|J3QR02_HUMAN,tr|X6RLV5|X6RLV5_HUMAN,tr|A0A7I2V507|A0A7I2V507_HUMAN,tr|J3KTA4|J3KTA4_HUMAN,tr|J3KTQ4|J3KTQ4_HUMAN,tr|A0A7I2V2S0|A0A7I2V2S0_HUMAN,tr|J3QRQ7|J3QRQ7_HUMAN" 8 1545.8191 1.87 87815 20086 4 1545.813835 387.4621 Probable ATP-dependent RNA helicase DDX5 OS=Homo sapiens OX=9606 GN=DDX5 PE=1 SV=1 6.18 3170 - 391711 - - - -3.4247 - 2.583 0.365 - 167.3 1 2 1 -0.0053 12 0 0 0 1.09E+07 5.83E+06 - - - 2.7606 0.9993 221125_WJC_METTL3_EV_vs_WT_F06.20089.20089.4 0.00023 17/156 R.FLAADGDPAR[166.11]PDGSWTFAQR[166.11]PTEQELR[166.11].A sp|Q9ULW3|ABT1_HUMAN 1 3060.4832 0.8 87816 20089 4 3060.470901 766.1281 Activator of basal transcription 1 OS=Homo sapiens OX=9606 GN=ABT1 PE=1 SV=1 4.44 3170.4 - 5.10E+06 - - - -4.0209 - 2.579 0.415 - 76.5 1 2 0 -0.0123 27 0 0 0 5.66E+07 7.05E+07 - - - 3.1312 0.9999 221125_WJC_METTL3_EV_vs_WT_F06.20092.20092.3 1.98E-05 14/68 R.SSPWSVVEASVKPGSSTR.S "sp|Q9BVN2|RUSC1_HUMAN,tr|A0A087WW20|A0A087WW20_HUMAN,tr|A0A087WVK5|A0A087WVK5_HUMAN,tr|A0A087WX95|A0A087WX95_HUMAN" 4 1859.9377 1.2 87819 20092 3 1859.932756 620.9865 AP-4 complex accessory subunit RUSC1 OS=Homo sapiens OX=9606 GN=RUSC1 PE=1 SV=3 8.46 3170.8 - 559685 - - - -2.6802 - 2.738 0.446 - 167.6 1 2 0 -0.005 18 0 0 0 2.30E+07 1.91E+07 - - - 6.0192 0.9999 221125_WJC_METTL3_EV_vs_WT_F06.20107.20107.3 5.89E-10 18/88 R.EAAVSASDILQESAIHSPGTVEK[136.11].E "sp|Q96C57|CSTOS_HUMAN,tr|G5EA44|G5EA44_HUMAN,tr|E7ENF1|E7ENF1_HUMAN,tr|F5H3K2|F5H3K2_HUMAN,tr|F5H8B7|F5H8B7_HUMAN,tr|F5H7W8|F5H7W8_HUMAN" 6 2346.1794 2.68 87826 20107 3 2346.169412 783.0671 Protein CUSTOS OS=Homo sapiens OX=9606 GN=CUSTOS PE=1 SV=2 4.4 3172.8 - 2.96E+06 - - - -4.2721 - 3.615 0.559 - 349.8 1 2 0 -0.01 23 0 0 0 9.97E+07 3.73E+07 - - - 7.7843 0.9998 221125_WJC_METTL3_EV_vs_WT_F06.20110.20110.4 0.000112 15/120 K.FLVNLDPSHC[160.03]SNNGTVHLIC[160.03]K.L "sp|Q96RN5|MED15_HUMAN,tr|G3V1P5|G3V1P5_HUMAN" 2 2424.1678 1.79 87827 20110 4 2424.163151 607.0492 Mediator of RNA polymerase II transcription subunit 15 OS=Homo sapiens OX=9606 GN=MED15 PE=1 SV=2 6.9 3173.1 - 4.43E+06 - - - -1.9322 - 2.774 0.407 - 85.1 1 2 0 -0.0047 21 0 0 0 1.41E+08 7.90E+07 - - - 3.1046 0.9999 221125_WJC_METTL3_EV_vs_WT_F06.20113.20113.4 8.58E-06 27/162 R.APVSALPLAPNHLGGGAVVLGAESHASK[136.11].D "sp|Q13190|STX5_HUMAN,tr|H7C3X5|H7C3X5_HUMAN" 2 2627.4275 1.35 87828 20113 4 2627.418877 657.8641 Syntaxin-5 OS=Homo sapiens OX=9606 GN=STX5 PE=1 SV=2 6.96 3173.5 - 3.53E+06 - - - -3.2762 - 4.089 0.505 - 325.3 1 2 0 -0.0086 28 0 0 0 3.11E+08 2.31E+08 - - - 4.0564 0.9971 221125_WJC_METTL3_EV_vs_WT_F06.20115.20115.3 0.0218 21/104 R.IGQELLFPPQENVQDAGAPGGHTQNLR.C sp|Q5JSZ5|PRC2B_HUMAN 1 2885.442 1.91 87829 20115 3 2885.434119 962.8213 Protein PRRC2B OS=Homo sapiens OX=9606 GN=PRRC2B PE=1 SV=2 4.65 3173.7 - 4.87E+06 - - - -2.7379 - 2.264 0.263 - 137.3 1 2 0 -0.0079 27 0 0 0 1.79E+08 9.40E+07 - - - 3.3499 1 221125_WJC_METTL3_EV_vs_WT_F06.20125.20125.2 8.38E-17 24/40 R.QVQSLTC[160.03]EVDALKGTNESLER.Q "sp|P08670|VIME_HUMAN,tr|B0YJC5|B0YJC5_HUMAN,tr|B0YJC4|B0YJC4_HUMAN" 3 2376.1591 2.32 87835 20125 2 2376.151569 1189.0868 Vimentin OS=Homo sapiens OX=9606 GN=VIM PE=1 SV=4 4.41 3174.8 - 4.23E+06 - - - -3.1711 - 4.462 0.733 - 1479.8 1 2 1 -0.0075 21 0 0 0 1.53E+08 6.59E+07 - - - 8.1296 0.9999 221125_WJC_METTL3_EV_vs_WT_F06.20128.20128.3 1.14E-08 25/84 R.YSDKYNVPISSADIAQNQEFYK.N "sp|Q9H334|FOXP1_HUMAN,tr|G5E965|G5E965_HUMAN,tr|A0A3B3IST0|A0A3B3IST0_HUMAN,tr|A0A3B3IT14|A0A3B3IT14_HUMAN,tr|C9J0F0|C9J0F0_HUMAN,tr|H0Y882|H0Y882_HUMAN,tr|A0A3B3IT66|A0A3B3IT66_HUMAN,tr|A0A3B3IS87|A0A3B3IS87_HUMAN,tr|A0A0B4J2F3|A0A0B4J2F3_HUMAN,tr|A0A3B3IST6|A0A3B3IST6_HUMAN" 10 2579.218 0.26 87836 20128 3 2579.214668 860.7466 Forkhead box protein P1 OS=Homo sapiens OX=9606 GN=FOXP1 PE=1 SV=1 4.56 3175.2 - 2.76E+06 - - - -1.2915 - 3.614 0.596 - 474.6 1 2 1 -0.0033 22 0 0 0 1.60E+08 6.17E+08 - - - 8.23 0.9999 221125_WJC_METTL3_EV_vs_WT_F06.20130.20130.4 0.0011 23/162 R.APVSALPLAPNHLGGGAVVLGAESHASK.D "sp|Q13190|STX5_HUMAN,tr|H7C3X5|H7C3X5_HUMAN" 2 2619.4133 1.35 87837 20130 4 2619.411856 655.8606 Syntaxin-5 OS=Homo sapiens OX=9606 GN=STX5 PE=1 SV=2 6.96 3175.4 - 9.20E+06 - - - -0.5455 - 3.63 0.443 - 228.2 1 2 0 -0.0014 28 0 0 0 3.11E+08 2.31E+08 - - - 3.4818 1 221125_WJC_METTL3_EV_vs_WT_F06.20137.20137.3 1.21E-10 21/104 R.IGQELLFPPQENVQDAGAPGGHTQNLR[166.11].C sp|Q5JSZ5|PRC2B_HUMAN 1 2895.4503 1.91 87841 20137 3 2895.444678 966.1574 Protein PRRC2B OS=Homo sapiens OX=9606 GN=PRRC2B PE=1 SV=2 4.65 3176.2 - 1.66E+06 - - - -1.9379 - 3.598 0.6 - 254.1 1 2 0 -0.0056 27 0 0 0 1.42E+08 7.45E+07 - - - 8.1735 1 221125_WJC_METTL3_EV_vs_WT_F06.20141.20141.2 6.12E-16 24/40 R.QVQSLTC[160.03]EVDALK[136.11]GTNESLER[166.11].Q "sp|P08670|VIME_HUMAN,tr|B0YJC5|B0YJC5_HUMAN,tr|B0YJC4|B0YJC4_HUMAN" 3 2394.1816 2.32 87843 20141 2 2394.172531 1198.0981 Vimentin OS=Homo sapiens OX=9606 GN=VIM PE=1 SV=4 4.41 3176.8 - 2.96E+06 - - - -3.7771 - 4.414 0.701 - 1564.4 1 2 1 -0.009 21 0 0 0 1.53E+08 6.59E+07 - - - 7.8661 0.9999 221125_WJC_METTL3_EV_vs_WT_F06.20143.20143.3 1.11E-08 18/72 K.TNGLPVQNGIDADVK[136.11]DFSR[166.11].T "sp|Q14671|PUM1_HUMAN,tr|Q5T1Z8|Q5T1Z8_HUMAN,tr|H0YEH2|H0YEH2_HUMAN,tr|Q5T1Z4|Q5T1Z4_HUMAN" 4 2063.0403 2.58 87844 20143 3 2063.036573 688.6874 Pumilio homolog 1 OS=Homo sapiens OX=9606 GN=PUM1 PE=1 SV=3 4.43 3177 - 1.29E+06 - - - -1.7833 - 3.18 0.612 - 290.3 1 2 1 -0.0037 19 0 0 0 4.35E+08 1.68E+08 - - - 8.2044 0.9999 221125_WJC_METTL3_EV_vs_WT_F06.20148.20148.4 1.71E-09 28/120 R.QVQSLTC[160.03]EVDALKGTNESLER.Q "sp|P08670|VIME_HUMAN,tr|B0YJC5|B0YJC5_HUMAN,tr|B0YJC4|B0YJC4_HUMAN" 3 2376.1591 1.61 87846 20148 4 2376.154731 595.0471 Vimentin OS=Homo sapiens OX=9606 GN=VIM PE=1 SV=4 4.41 3177.6 - 4.40E+06 - - - -1.8404 - 3.989 0.564 - 504.7 1 2 1 -0.0044 21 0 0 0 6.79E+07 4.21E+07 - - - 4.5913 0.8028 221125_WJC_METTL3_EV_vs_WT_F06.20153.20153.3 0.000448 16/100 K.NGFSSVQATQLQTTQSVEGATGSAVK[136.11].S "sp|Q14157|UBP2L_HUMAN,tr|F8W726|F8W726_HUMAN" 2 2603.2918 -1 87848 20153 3 2604.269775 868.7712 Ubiquitin-associated protein 2-like OS=Homo sapiens OX=9606 GN=UBAP2L PE=1 SV=2 6 3178.2 - 5.84E+06 - - - 375.6536 - 3.051 0.426 - 235.5 1 2 0 0.9779 26 0 0 0 0.00E+00 0.00E+00 - - - 5.5849 1 221125_WJC_METTL3_EV_vs_WT_F06.20155.20155.3 2.09E-10 23/72 K.TNGLPVQNGIDADVKDFSR.T "sp|Q14671|PUM1_HUMAN,tr|Q5T1Z8|Q5T1Z8_HUMAN,tr|H0YEH2|H0YEH2_HUMAN,tr|Q5T1Z4|Q5T1Z4_HUMAN" 4 2045.0178 2.59 87849 20155 3 2045.013548 682.6799 Pumilio homolog 1 OS=Homo sapiens OX=9606 GN=PUM1 PE=1 SV=3 4.43 3178.4 - 3.66E+06 - - - -2.0704 - 3.869 0.665 - 571.6 1 2 1 -0.0042 19 0 0 0 4.36E+08 1.68E+08 - - - 9.277 1 221125_WJC_METTL3_EV_vs_WT_F06.20159.20159.3 5.76E-11 18/72 R.AQC[160.03]YMDTEQYEEAVR[166.11]DYEK[136.11].V "sp|Q99615|DNJC7_HUMAN,tr|A0A6I8PRZ0|A0A6I8PRZ0_HUMAN,tr|A0A6I8PLE7|A0A6I8PLE7_HUMAN,tr|A0A6I8PR89|A0A6I8PR89_HUMAN,tr|A0A6I8PIK4|A0A6I8PIK4_HUMAN,tr|A0A6I8PS32|A0A6I8PS32_HUMAN,tr|A0A6I8PUD4|A0A6I8PUD4_HUMAN,tr|A0A6I8PU73|A0A6I8PU73_HUMAN" 8 2445.022 0.41 87852 20159 3 2445.003277 816.0146 DnaJ homolog subfamily C member 7 OS=Homo sapiens OX=9606 GN=DNAJC7 PE=1 SV=2 4.08 3178.8 - 3.42E+06 - - - -7.6416 - 3.828 0.755 - 376.5 1 2 1 -0.0187 19 0 0 0 1.14E+07 2.80E+07 - - - 10.2502 1 221125_WJC_METTL3_EV_vs_WT_F06.20165.20165.3 1.36E-09 24/72 K.SIEEQLGTEIKPIPSNIDK.S sp|P26196|DDX6_HUMAN 1 2110.1158 1.13 87856 20165 3 2110.113884 704.3792 Probable ATP-dependent RNA helicase DDX6 OS=Homo sapiens OX=9606 GN=DDX6 PE=1 SV=2 4.41 3179.5 - 3.08E+06 - - - -0.8914 - 3.74 0.687 - 381.9 1 2 0 -0.0019 19 0 0 0 1.66E+08 1.48E+08 - - - 9.4396 1 221125_WJC_METTL3_EV_vs_WT_F06.20167.20167.2 7.10E-12 15/28 K.QC[160.03]ANLQAAIADAEQR.G "sp|P04259|K2C6B_HUMAN,sp|P02538|K2C6A_HUMAN" 2 1657.7842 999 87858 20167 2 1657.780519 829.8994 "Keratin, type II cytoskeletal 6B OS=Homo sapiens OX=9606 GN=KRT6B PE=1 SV=5" 4.37 3179.7 - 965007 - - - -2.2313 - 3.197 0.661 - 906.6 1 2 0 -0.0037 15 0 0 0 3.03E+07 0.00E+00 - - - 6.7793 1 221125_WJC_METTL3_EV_vs_WT_F06.20170.20170.2 1.44E-05 16/50 K.NGFSSVQATQLQTTQSVEGATGSAVK.S "sp|Q14157|UBP2L_HUMAN,tr|F8W726|F8W726_HUMAN" 2 2595.2776 -1 87859 20170 2 2598.265447 1298.6461 Ubiquitin-associated protein 2-like OS=Homo sapiens OX=9606 GN=UBAP2L PE=1 SV=2 6 3180.1 - 1.95E+06 - - - 1151.2479 - 3.606 0.651 - 634.4 1 2 0 2.9878 26 0 0 0 0.00E+00 0.00E+00 - - - 6.0644 0.9988 221125_WJC_METTL3_EV_vs_WT_F06.20177.20177.3 7.21E-10 20/52 K.TLNNKFASFIDKVR.F "sp|Q9NSB2|KRT84_HUMAN,sp|P48668|K2C6C_HUMAN,sp|P05787|K2C8_HUMAN,sp|Q01546|K22O_HUMAN,sp|P12035|K2C3_HUMAN,sp|P04259|K2C6B_HUMAN,sp|P13647|K2C5_HUMAN,sp|P35908|K22E_HUMAN,sp|P08729|K2C7_HUMAN,sp|O95678|K2C75_HUMAN,sp|Q5XKE5|K2C79_HUMAN,sp|P02538|K2C6A_HUMAN,tr|F8VUG2|F8VUG2_HUMAN,tr|F8W0C6|F8W0C6_HUMAN,tr|F8W1U3|F8W1U3_HUMAN" 15 1651.9046 42.81 87864 20177 3 1651.895487 551.6421 "Keratin, type II cuticular Hb4 OS=Homo sapiens OX=9606 GN=KRT84 PE=2 SV=2" 9.99 3181 - 1.38E+06 - - - -5.5106 - 2.93 0.596 - 516.5 1 2 2 -0.0091 14 0 0 0 2.52E+07 5.89E+05 - - - 8.0391 0.9988 221125_WJC_METTL3_EV_vs_WT_F06.20180.20180.3 7.05E-08 19/64 K.LHEEEIQELQAQIQEQH.V "sp|P08670|VIME_HUMAN,tr|B0YJC5|B0YJC5_HUMAN,tr|B0YJC4|B0YJC4_HUMAN" 3 2101.0076 - 87865 20180 3 2101.006957 701.3431 Vimentin OS=Homo sapiens OX=9606 GN=VIM PE=1 SV=4 4.31 3181.4 - 2.54E+06 - - - -0.3118 - 3.702 0.551 - 653.8 1 1 0 -0.0007 17 0 0 0 - - - - - 7.9895 1 221125_WJC_METTL3_EV_vs_WT_F06.20183.20183.4 5.71E-07 25/120 R.K[136.11]HPDADSLYVEEVDVGEIAPR[166.11].T "sp|Q12904|AIMP1_HUMAN,tr|A0A804HJ47|A0A804HJ47_HUMAN,tr|A0A5F9ZHC5|A0A5F9ZHC5_HUMAN" 3 2356.1666 1.48 87868 20183 4 2356.166196 590.0489 Aminoacyl tRNA synthase complex-interacting multifunctional protein 1 OS=Homo sapiens OX=9606 GN=AIMP1 PE=1 SV=2 4.29 3181.7 - 1.78E+06 - - - -0.1609 - 4.324 0.561 - 485.3 1 2 0 -0.0004 21 0 0 0 2.91E+07 1.96E+07 - - - 4.593 1 221125_WJC_METTL3_EV_vs_WT_F06.20184.20184.2 1.17E-07 16/50 K.NGFSSVQATQLQTTQSVEGATGSAVK[136.11].S "sp|Q14157|UBP2L_HUMAN,tr|F8W726|F8W726_HUMAN" 2 2603.2918 -1 87869 20184 2 2604.273007 1302.6532 Ubiquitin-associated protein 2-like OS=Homo sapiens OX=9606 GN=UBAP2L PE=1 SV=2 6 3181.9 - 1.36E+06 - - - 376.8951 - 3.691 0.68 - 667.3 1 2 0 0.9812 26 0 0 0 0.00E+00 0.00E+00 - - - 6.966 0.9998 221125_WJC_METTL3_EV_vs_WT_F06.20192.20192.4 8.85E-09 19/78 K.TLNNKFASFIDKVR.F "sp|Q9NSB2|KRT84_HUMAN,sp|P48668|K2C6C_HUMAN,sp|P05787|K2C8_HUMAN,sp|Q01546|K22O_HUMAN,sp|P12035|K2C3_HUMAN,sp|P04259|K2C6B_HUMAN,sp|P13647|K2C5_HUMAN,sp|P35908|K22E_HUMAN,sp|P08729|K2C7_HUMAN,sp|O95678|K2C75_HUMAN,sp|Q5XKE5|K2C79_HUMAN,sp|P02538|K2C6A_HUMAN,tr|F8VUG2|F8VUG2_HUMAN,tr|F8W0C6|F8W0C6_HUMAN,tr|F8W1U3|F8W1U3_HUMAN" 15 1651.9046 999 87876 20192 4 1651.901941 413.9834 "Keratin, type II cuticular Hb4 OS=Homo sapiens OX=9606 GN=KRT84 PE=2 SV=2" 9.99 3182.8 - 684154 - - - -1.6036 - 2.94 0.463 - 315.8 1 2 2 -0.0027 14 0 0 0 2.76E+07 0.00E+00 - - - 3.6477 1 221125_WJC_METTL3_EV_vs_WT_F06.20198.20198.3 1.45E-11 27/96 R.HQILLLASQNADLPTSSSPSQGTLR.T "sp|Q9NSC2|SALL1_HUMAN,tr|H3BSM9|H3BSM9_HUMAN" 2 2633.3773 2.21 87880 20198 3 2633.374481 878.7997 Sal-like protein 1 OS=Homo sapiens OX=9606 GN=SALL1 PE=1 SV=2 6.74 3183.4 - 2.28E+06 - - - -1.0678 - 4.533 0.688 - 601.8 1 2 0 -0.0028 25 0 0 0 3.02E+07 1.37E+07 - - - 9.6869 0.9996 221125_WJC_METTL3_EV_vs_WT_F06.20202.20202.3 3.05E-06 14/72 K.SSGDVHLSISSDVSTFTTR[166.11].T "sp|Q13492|PICAL_HUMAN,tr|H0YD48|H0YD48_HUMAN,tr|H0YEF7|H0YEF7_HUMAN" 3 2004.9628 3.94 87884 20202 3 2004.970506 669.3282 Phosphatidylinositol-binding clathrin assembly protein OS=Homo sapiens OX=9606 GN=PICALM PE=1 SV=2 5.19 3184 - 709536 - - - 3.8519 - 3.072 0.399 - 175 1 2 0 0.0077 19 0 0 0 1.77E+07 4.48E+06 - - - 5.7437 0.986 221125_WJC_METTL3_EV_vs_WT_F06.20206.20206.4 1.14E-10 30/114 K.RPVFPPLC[160.03]GDGLLSGKEETR.K "sp|Q9NRX1|PNO1_HUMAN,tr|F8WBJ6|F8WBJ6_HUMAN" 2 2227.1419 0.39 87886 20206 4 2228.13549 557.7928 RNA-binding protein PNO1 OS=Homo sapiens OX=9606 GN=PNO1 PE=1 SV=1 6.17 3184.5 - 2.92E+06 - - - 446.1112 - 4.399 0.636 - 498.5 1 2 1 0.9936 20 0 0 0 3.11E+07 8.00E+07 - - - 4.9818 1 221125_WJC_METTL3_EV_vs_WT_F06.20211.20211.4 3.59E-08 26/144 K.LILSLDKDTYEETGLQGHPSQFSGR.K "sp|O75818|RPP40_HUMAN,tr|A0A087X1N3|A0A087X1N3_HUMAN,tr|X6RLL4|X6RLL4_HUMAN" 3 2790.3824 2.4 87889 20211 4 2790.382112 698.6029 Ribonuclease P protein subunit p40 OS=Homo sapiens OX=9606 GN=RPP40 PE=1 SV=3 4.75 3185.1 - 3.84E+06 - - - -0.1168 - 4.974 0.616 - 272.5 1 2 1 -0.0003 25 0 0 0 5.40E+07 2.25E+07 - - - 5.0979 1 221125_WJC_METTL3_EV_vs_WT_F06.20216.20216.3 4.44E-10 35/112 R.SFREPAPAEALPQQYPEPAPAALC[160.03]GPPPR.A sp|Q8IU81|I2BP1_HUMAN 1 3113.5393 2.04 87894 20216 3 3113.543552 1038.8537 Interferon regulatory factor 2-binding protein 1 OS=Homo sapiens OX=9606 GN=IRF2BP1 PE=1 SV=1 4.78 3185.6 - 1.26E+06 - - - 1.3689 - 5.837 0.671 - 869.8 1 2 1 0.0043 29 0 0 0 8.48E+07 4.15E+07 - - - 10.0786 0.9994 221125_WJC_METTL3_EV_vs_WT_F06.20218.20218.4 0.0015 15/96 K.SDKLVYVDLLREEPDAK.T "sp|Q6W2J9|BCOR_HUMAN,tr|H7BZ37|H7BZ37_HUMAN,tr|A1A564|A1A564_HUMAN,tr|H7C2V9|H7C2V9_HUMAN,tr|H7BYY2|H7BYY2_HUMAN,tr|H7C231|H7C231_HUMAN" 6 1989.0419 2.23 87896 20218 4 1989.042836 498.2677 BCL-6 corepressor OS=Homo sapiens OX=9606 GN=BCOR PE=1 SV=1 4.44 3185.9 - 653048 - - - 0.4847 - 2.733 0.39 - 185.3 1 2 2 0.001 17 0 0 0 8.29E+06 3.72E+06 - - - 2.9694 0.996 221125_WJC_METTL3_EV_vs_WT_F06.20221.20221.4 1.80E-07 20/156 Q.QLPHGLGGIGMGLGPGGQPIDANHLNK.G "sp|P52272|HNRPM_HUMAN,tr|M0R019|M0R019_HUMAN,tr|M0R0N3|M0R0N3_HUMAN,tr|M0QYL3|M0QYL3_HUMAN,tr|A0A087X0X3|A0A087X0X3_HUMAN,tr|M0QZM1|M0QZM1_HUMAN" 6 2647.3653 2.2 87897 20221 4 2647.364151 662.8486 Heterogeneous nuclear ribonucleoprotein M OS=Homo sapiens OX=9606 GN=HNRNPM PE=1 SV=3 6.92 3186.3 - 4.28E+06 - - - -0.4299 - 3.523 0.498 - 194.6 1 1 0 -0.0011 27 0 0 0 6.33E+07 2.88E+07 - - - 3.9543 1 221125_WJC_METTL3_EV_vs_WT_F06.20223.20223.3 1.75E-18 28/92 K.FAC[160.03]NGTVIEHPEYGEVIQLQGDQR.K "sp|P41567|EIF1_HUMAN,sp|O60739|EIF1B_HUMAN,tr|K7EM18|K7EM18_HUMAN,tr|K7EQP2|K7EQP2_HUMAN" 4 2759.2973 1.18 87899 20223 3 2759.287861 920.7731 Eukaryotic translation initiation factor 1 OS=Homo sapiens OX=9606 GN=EIF1 PE=1 SV=1 4.4 3186.5 - 2.77E+06 - - - -3.4313 - 4.874 0.729 - 788.5 1 2 0 -0.0095 24 0 0 0 5.66E+07 4.78E+07 - - - 10.3438 1 221125_WJC_METTL3_EV_vs_WT_F06.20224.20224.3 4.01E-08 26/68 K.VTSEELHYFVQNHFTSAR.M "sp|P22695|QCR2_HUMAN,tr|H3BRG4|H3BRG4_HUMAN,tr|H3BSJ9|H3BSJ9_HUMAN" 3 2164.0338 1.14 87900 20224 3 2164.034582 722.3519 "Cytochrome b-c1 complex subunit 2, mitochondrial OS=Homo sapiens OX=9606 GN=UQCRC2 PE=1 SV=3" 6 3186.6 - 2.01E+06 - - - 0.3766 - 4.415 0.624 - 1292.6 1 2 0 0.0008 18 0 0 0 3.56E+07 3.12E+07 - - - 9.1946 1 221125_WJC_METTL3_EV_vs_WT_F06.20225.20225.3 2.21E-12 27/88 R.SYIDRDSEYLLQENEPDGTLDQK.L "sp|Q9H2U1|DHX36_HUMAN,tr|E7EWK3|E7EWK3_HUMAN" 2 2727.2511 1.21 87901 20225 3 2727.250725 910.091 ATP-dependent DNA\RNA helicase DHX36 OS=Homo sapiens OX=9606 GN=DHX36 PE=1 SV=2 3.9 3186.7 - 1.96E+06 - - - -0.1555 - 4.531 0.657 - 728.7 1 2 1 -0.0004 23 0 0 0 4.67E+07 3.85E+07 - - - 9.4094 0.9975 221125_WJC_METTL3_EV_vs_WT_F06.20229.20229.4 0.00156 14/72 R.EKVEVQLPELFHK.L "sp|Q13303|KCAB2_HUMAN,tr|A0A590UJJ4|A0A590UJJ4_HUMAN,tr|A0A5F9UN28|A0A5F9UN28_HUMAN,tr|A0A590UJB6|A0A590UJB6_HUMAN" 4 1594.8719 1.87 87905 20229 4 1594.869595 399.7252 Voltage-gated potassium channel subunit beta-2 OS=Homo sapiens OX=9606 GN=KCNAB2 PE=1 SV=2 5.5 3187.3 - 908609 - - - -1.4409 - 2.37 0.312 - 190 1 2 1 -0.0023 13 0 0 0 1.95E+08 1.04E+08 - - - 2.2609 1 221125_WJC_METTL3_EV_vs_WT_F06.20233.20233.3 3.10E-10 20/88 K.TDEFQLHTNVNDGTEFGGSIYQK.V sp|P21796|VDAC1_HUMAN 1 2599.1827 1.43 87907 20233 3 2599.17875 867.4015 Voltage-dependent anion-selective channel protein 1 OS=Homo sapiens OX=9606 GN=VDAC1 PE=1 SV=2 4.31 3187.7 - 2.86E+07 - - - -1.5105 - 3.552 0.626 - 384.3 1 2 0 -0.0039 23 0 0 0 2.55E+08 1.78E+08 - - - 8.4917 1 221125_WJC_METTL3_EV_vs_WT_F06.20235.20235.3 5.68E-10 24/88 K.TDEFQLHTNVNDGTEFGGSIYQK[136.11].V sp|P21796|VDAC1_HUMAN 1 2607.1969 1.44 87909 20235 3 2607.192492 870.0729 Voltage-dependent anion-selective channel protein 1 OS=Homo sapiens OX=9606 GN=VDAC1 PE=1 SV=2 4.31 3187.8 - 2.06E+07 - - - -1.6815 - 4.526 0.686 - 769.2 1 2 0 -0.0044 23 0 0 0 2.56E+08 1.79E+08 - - - 9.729 1 221125_WJC_METTL3_EV_vs_WT_F06.20236.20236.4 8.25E-12 20/102 K.VTSEELHYFVQNHFTSAR.M "sp|P22695|QCR2_HUMAN,tr|H3BRG4|H3BRG4_HUMAN,tr|H3BSJ9|H3BSJ9_HUMAN" 3 2164.0338 0.88 87910 20236 4 2164.034394 542.0157 "Cytochrome b-c1 complex subunit 2, mitochondrial OS=Homo sapiens OX=9606 GN=UQCRC2 PE=1 SV=3" 6 3187.8 - 6.50E+06 - - - 0.2897 - 3.731 0.629 - 412.6 1 2 0 0.0006 18 0 0 0 1.00E+08 1.15E+08 - - - 5.1517 1 221125_WJC_METTL3_EV_vs_WT_F06.20237.20237.3 2.14E-15 24/92 K.FAC[160.03]NGTVIEHPEYGEVIQLQGDQR[166.11].K "sp|P41567|EIF1_HUMAN,sp|O60739|EIF1B_HUMAN,tr|K7EM18|K7EM18_HUMAN,tr|K7EQP2|K7EQP2_HUMAN" 4 2769.3056 1.18 87911 20237 3 2769.300608 924.1091 Eukaryotic translation initiation factor 1 OS=Homo sapiens OX=9606 GN=EIF1 PE=1 SV=1 4.4 3187.9 - 3.74E+06 - - - -1.8023 - 4.209 0.705 - 491.8 1 2 0 -0.005 24 0 0 0 5.66E+07 4.78E+07 - - - 9.7368 1 221125_WJC_METTL3_EV_vs_WT_F06.20238.20238.3 3.55E-09 23/72 K.MQAHIQDLEEQLDEEEGAR.Q sp|P35580|MYH10_HUMAN 1 2240.0015 1.12 87912 20238 3 2240.001576 747.6745 Myosin-10 OS=Homo sapiens OX=9606 GN=MYH10 PE=1 SV=3 4 3188 - 3.31E+06 - - - 0.0161 - 4.385 0.671 - 733.6 1 2 0 0 19 0 0 0 7.33E+07 6.56E+07 - - - 9.6526 0.9999 221125_WJC_METTL3_EV_vs_WT_F06.20241.20241.3 0.391 16/92 K.QHSSFGYGGLQGPASGLNAC[160.03]QYNS.- sp|P78337|PITX1_HUMAN 1 2499.0873 - 87915 20241 3 2499.083193 834.0364 Pituitary homeobox 1 OS=Homo sapiens OX=9606 GN=PITX1 PE=1 SV=2 6.73 3188.4 - 1.23E+06 - - - -1.6578 - 2.782 0.394 - 210.4 1 2 0 -0.0041 24 0 0 0 - - - - - 5.308 1 221125_WJC_METTL3_EV_vs_WT_F06.20242.20242.4 7.74E-09 28/168 R.SFR[166.11]EPAPAEALPQQYPEPAPAALC[160.03]GPPPR[166.11].A sp|Q8IU81|I2BP1_HUMAN 1 3133.5558 23.93 87916 20242 4 3133.55931 784.3962 Interferon regulatory factor 2-binding protein 1 OS=Homo sapiens OX=9606 GN=IRF2BP1 PE=1 SV=1 4.78 3188.5 - 1.22E+06 - - - 1.1106 - 4.596 0.614 - 489.9 1 2 1 0.0035 29 0 0 0 6.63E+08 2.77E+07 - - - 5.0393 1 221125_WJC_METTL3_EV_vs_WT_F06.20246.20246.4 8.05E-06 16/102 K.VTSEELHYFVQNHFTSAR[166.11].M "sp|P22695|QCR2_HUMAN,tr|H3BRG4|H3BRG4_HUMAN,tr|H3BSJ9|H3BSJ9_HUMAN" 3 2174.042 1.35 87918 20246 4 2174.040537 544.5178 "Cytochrome b-c1 complex subunit 2, mitochondrial OS=Homo sapiens OX=9606 GN=UQCRC2 PE=1 SV=3" 6 3189 - 3.83E+06 - - - -0.69 - 3.288 0.564 - 209.1 1 2 0 -0.0015 18 0 0 0 9.28E+07 6.87E+07 - - - 4.5424 1 221125_WJC_METTL3_EV_vs_WT_F06.20247.20247.3 3.56E-12 29/88 R.SYIDR[166.11]DSEYLLQENEPDGTLDQK[136.11].L "sp|Q9H2U1|DHX36_HUMAN,tr|E7EWK3|E7EWK3_HUMAN" 2 2745.2736 1.21 87919 20247 3 2745.272192 916.0985 ATP-dependent DNA\RNA helicase DHX36 OS=Homo sapiens OX=9606 GN=DHX36 PE=1 SV=2 3.9 3189.1 - 3.02E+06 - - - -0.5198 - 4.446 0.68 - 926.8 1 2 1 -0.0014 23 0 0 0 4.67E+07 3.85E+07 - - - 9.6211 1 221125_WJC_METTL3_EV_vs_WT_F06.20250.20250.3 3.35E-08 21/68 K.VTSEELHYFVQNHFTSAR[166.11].M "sp|P22695|QCR2_HUMAN,tr|H3BRG4|H3BRG4_HUMAN,tr|H3BSJ9|H3BSJ9_HUMAN" 3 2174.042 1.14 87922 20250 3 2174.043912 725.688 "Cytochrome b-c1 complex subunit 2, mitochondrial OS=Homo sapiens OX=9606 GN=UQCRC2 PE=1 SV=3" 6 3189.4 - 1.78E+06 - - - 0.8624 - 3.918 0.575 - 628.4 1 2 0 0.0019 18 0 0 0 3.56E+07 3.12E+07 - - - 8.3506 1 221125_WJC_METTL3_EV_vs_WT_F06.20251.20251.4 1.20E-05 15/108 R.GLLQDDAHPTLVTYADHSK[136.11].L "sp|Q86U44|MTA70_HUMAN,tr|F5H6D8|F5H6D8_HUMAN,tr|H0YFV6|H0YFV6_HUMAN,tr|B4DTN4|B4DTN4_HUMAN" 4 2088.0367 0.01 87923 20251 4 2088.035005 523.0165 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 5.13 3189.4 - 1.74E+06 - - - -0.8276 - 3.041 0.51 - 219.9 1 2 0 -0.0017 19 0 0 0 1.02E+05 1.60E+07 - - - 4.0408 0.9988 221125_WJC_METTL3_EV_vs_WT_F06.20252.20252.3 5.59E-08 17/80 K.GILGYTEHQVVSSDFNSDTHS.S "sp|P04406|G3P_HUMAN,tr|E7EUT5|E7EUT5_HUMAN" 2 2292.0295 - 87924 20252 3 2292.029469 765.0171 Glyceraldehyde-3-phosphate dehydrogenase OS=Homo sapiens OX=9606 GN=GAPDH PE=1 SV=3 4.52 3189.5 - 1.26E+06 - - - 0 - 2.701 0.636 - 262 1 1 0 0 21 0 0 0 - - - - - 8.0129 0.9905 221125_WJC_METTL3_EV_vs_WT_F06.20253.20253.4 0.096 15/72 R.EK[136.11]VEVQLPELFHK[136.11].L "sp|Q13303|KCAB2_HUMAN,tr|A0A590UJJ4|A0A590UJJ4_HUMAN,tr|A0A5F9UN28|A0A5F9UN28_HUMAN,tr|A0A590UJB6|A0A590UJB6_HUMAN" 4 1610.9003 1.87 87925 20253 4 1610.899264 403.7323 Voltage-gated potassium channel subunit beta-2 OS=Homo sapiens OX=9606 GN=KCNAB2 PE=1 SV=2 5.5 3189.7 - 377963 - - - -0.6388 - 2.434 0.246 - 266.4 1 2 1 -0.001 13 0 0 0 1.95E+08 1.04E+08 - - - 1.6967 1 221125_WJC_METTL3_EV_vs_WT_F06.20255.20255.3 8.47E-09 25/92 K.EGTLTQVPLAPPPPGAPPSPAPAR.F sp|P48634|PRC2A_HUMAN 1 2317.243 1.82 87926 20255 3 2317.241622 773.4216 Protein PRRC2A OS=Homo sapiens OX=9606 GN=PRRC2A PE=1 SV=3 6.1 3189.9 - 1.42E+06 - - - -0.6081 - 3.511 0.539 - 599 1 2 0 -0.0014 24 0 0 0 2.68E+08 1.47E+08 - - - 7.4659 0.9962 221125_WJC_METTL3_EV_vs_WT_F06.20258.20258.3 0.0185 Nov-48 R.EKVEVQLPELFHK.L "sp|Q13303|KCAB2_HUMAN,tr|A0A590UJJ4|A0A590UJJ4_HUMAN,tr|A0A5F9UN28|A0A5F9UN28_HUMAN,tr|A0A590UJB6|A0A590UJB6_HUMAN" 4 1594.8719 1.61 87928 20258 3 1594.87161 532.6312 Voltage-gated potassium channel subunit beta-2 OS=Homo sapiens OX=9606 GN=KCNAB2 PE=1 SV=2 5.5 3190.2 - 622374 - - - -0.1774 - 2.17 0.252 - 157.1 1 2 1 -0.0003 13 0 0 0 1.22E+08 7.59E+07 - - - 3.45 1 221125_WJC_METTL3_EV_vs_WT_F06.20260.20260.3 1.32E-15 34/112 R.SFR[166.11]EPAPAEALPQQYPEPAPAALC[160.03]GPPPR[166.11].A sp|Q8IU81|I2BP1_HUMAN 1 3133.5558 2.06 87930 20260 3 3133.556717 1045.5259 Interferon regulatory factor 2-binding protein 1 OS=Homo sapiens OX=9606 GN=IRF2BP1 PE=1 SV=1 4.78 3190.4 - 1.57E+06 - - - 0.2831 - 4.914 0.706 - 815.2 1 2 1 0.0009 29 0 0 0 8.48E+07 4.12E+07 - - - 10.0738 0.9843 221125_WJC_METTL3_EV_vs_WT_F06.20261.20261.4 3.56E-05 14/132 R.VTASSGITIPKPPKPPDKPLMPY.M "sp|Q969G3|SMCE1_HUMAN,tr|A0A2R8Y855|A0A2R8Y855_HUMAN,tr|A0A2R8YEB8|A0A2R8YEB8_HUMAN,tr|B4DGM3|B4DGM3_HUMAN,tr|J3QKS7|J3QKS7_HUMAN,tr|J3QR61|J3QR61_HUMAN,tr|J3QKX6|J3QKX6_HUMAN" 7 2433.3342 3.11 87931 20261 4 2433.332314 609.3408 SWI\SNF-related matrix-associated actin-dependent regulator of chromatin subfamily E member 1 OS=Homo sapiens OX=9606 GN=SMARCE1 PE=1 SV=2 9.53 3190.6 - 634437 - - - -0.7566 - 2.558 0.402 - 70.2 1 1 0 -0.0018 23 0 0 0 1.13E+07 3.61E+06 - - - 3.0288 0.9981 221125_WJC_METTL3_EV_vs_WT_F06.20265.20265.4 3.85E-10 21/120 V.K[136.11]GNPQGFNQGLDC[160.03]DVIVAEVR[166.11].S sp|Q86U44|MTA70_HUMAN 1 2333.1553 0.1 87933 20265 4 2333.154834 584.2961 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 4.56 3191.1 - 1.04E+06 - - - -0.1993 - 3.514 0.579 - 220.3 1 1 0 -0.0005 21 0 0 0 1.06E+06 1.10E+07 - - - 4.681 0.9979 221125_WJC_METTL3_EV_vs_WT_F06.20267.20267.3 2.39E-07 18/72 R.GLLQDDAHPTLVTYADHSK[136.11].L "sp|Q86U44|MTA70_HUMAN,tr|F5H6D8|F5H6D8_HUMAN,tr|H0YFV6|H0YFV6_HUMAN,tr|B4DTN4|B4DTN4_HUMAN" 4 2088.0367 0.03 87935 20267 3 2089.036141 697.0195 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 5.13 3191.3 - 1.17E+06 - - - 478.6353 - 2.993 0.459 - 303 1 2 0 0.9994 19 0 0 0 1.33E+06 4.35E+07 - - - 6.0739 1 221125_WJC_METTL3_EV_vs_WT_F06.20268.20268.2 2.18E-14 19/40 V.K[136.11]GNPQGFNQGLDC[160.03]DVIVAEVR[166.11].S sp|Q86U44|MTA70_HUMAN 1 2333.1553 0.001 87936 20268 2 2333.152239 1167.5849 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 4.56 3191.4 - 651214 - - - -1.3115 - 3.745 0.645 - 477.2 1 1 0 -0.0031 21 0 0 0 0.00E+00 6.06E+06 - - - 7.0503 1 221125_WJC_METTL3_EV_vs_WT_F06.20277.20277.3 8.60E-09 25/72 K.MQAHIQDLEEQLDEEEGAR[166.11].Q sp|P35580|MYH10_HUMAN 1 2250.0098 1.11 87943 20277 3 2250.009585 751.0105 Myosin-10 OS=Homo sapiens OX=9606 GN=MYH10 PE=1 SV=3 4 3192.4 - 3.39E+06 - - - -0.1 - 4.419 0.657 - 953.5 1 2 0 -0.0002 19 0 0 0 7.33E+07 6.59E+07 - - - 9.5154 0.9982 221125_WJC_METTL3_EV_vs_WT_F06.20278.20278.3 3.55E-10 19/88 E.QGEGSSGVSSLLLHPEPVPGPEK[136.11].E "sp|A0A1B0GTU1|ZC11B_HUMAN,sp|O75152|ZC11A_HUMAN,tr|E9PBY7|E9PBY7_HUMAN,tr|A0A1W2PPR9|A0A1W2PPR9_HUMAN,tr|A0A494C0C4|A0A494C0C4_HUMAN,tr|E9PQ61|E9PQ61_HUMAN" 6 2308.179 1.43 87944 20278 3 2308.179961 770.4003 Zinc finger CCCH domain-containing protein 11B OS=Homo sapiens OX=9606 GN=ZC3H11B PE=4 SV=1 4.75 3192.5 - 1.45E+06 - - - 0.3986 - 2.903 0.561 - 293.7 1 1 0 0.0009 23 0 0 0 5.40E+07 3.78E+07 - - - 7.2945 1 221125_WJC_METTL3_EV_vs_WT_F06.20282.20282.4 7.67E-05 18/102 K.AALLQLLAQHQPQDDPKR.E "sp|Q14004|CDK13_HUMAN,tr|A0A2R8Y4Z0|A0A2R8Y4Z0_HUMAN,tr|A0A2R8YF61|A0A2R8YF61_HUMAN,tr|A0A2R8Y7W5|A0A2R8Y7W5_HUMAN" 4 2041.1069 0.64 87948 20282 4 2041.106147 511.284 Cyclin-dependent kinase 13 OS=Homo sapiens OX=9606 GN=CDK13 PE=1 SV=2 6.79 3193 - 532812 - - - -0.3552 - 3.39 0.487 - 228.3 1 2 0 -0.0007 18 0 0 0 7.21E+06 1.12E+07 - - - 3.8829 0.9994 221125_WJC_METTL3_EV_vs_WT_F06.20283.20283.3 2.77E-06 18/60 K.DDPSK[136.11]PVHLTAFLGYK[136.11].A "sp|P39023|RL3_HUMAN,tr|H7C3M2|H7C3M2_HUMAN,tr|F8WCR1|F8WCR1_HUMAN,tr|H7C422|H7C422_HUMAN" 4 1802.9538 1.25 87949 20283 3 1802.943151 601.9919 60S ribosomal protein L3 OS=Homo sapiens OX=9606 GN=RPL3 PE=1 SV=2 6.75 3193.1 - 419356 - - - -5.8987 - 2.944 0.525 - 369.1 1 2 0 -0.0106 16 0 0 0 8.31E+07 6.67E+07 - - - 7.1608 1 221125_WJC_METTL3_EV_vs_WT_F06.20288.20288.3 1.42E-09 20/64 K.K[136.11]ANLQIDQINTDLNLER[166.11].S sp|P35579|MYH9_HUMAN 1 2015.0766 1.08 87952 20288 3 2015.077716 672.6995 Myosin-9 OS=Homo sapiens OX=9606 GN=MYH9 PE=1 SV=4 4.56 3193.7 - 3.32E+06 - - - 0.535 - 3.412 0.584 - 750.7 1 2 0 0.0011 17 0 0 0 1.09E+08 1.01E+08 - - - 8.1513 1 221125_WJC_METTL3_EV_vs_WT_F06.20289.20289.3 1.51E-09 17/64 K.KANLQIDQINTDLNLER.S sp|P35579|MYH9_HUMAN 1 1997.0542 1.08 87953 20289 3 1997.054783 666.692 Myosin-9 OS=Homo sapiens OX=9606 GN=MYH9 PE=1 SV=4 4.56 3193.8 - 3.69E+06 - - - 0.308 - 4.15 0.603 - 485.6 1 2 0 0.0006 17 0 0 0 1.09E+08 1.01E+08 - - - 8.8579 0.999 221125_WJC_METTL3_EV_vs_WT_F06.20290.20290.3 1.18E-08 21/88 E.QGEGSSGVSSLLLHPEPVPGPEK.E "sp|A0A1B0GTU1|ZC11B_HUMAN,sp|O75152|ZC11A_HUMAN,tr|E9PBY7|E9PBY7_HUMAN,tr|A0A1W2PPR9|A0A1W2PPR9_HUMAN,tr|A0A494C0C4|A0A494C0C4_HUMAN,tr|E9PQ61|E9PQ61_HUMAN" 6 2300.1648 1.43 87954 20290 3 2300.165956 767.7289 Zinc finger CCCH domain-containing protein 11B OS=Homo sapiens OX=9606 GN=ZC3H11B PE=4 SV=1 4.75 3193.9 - 2.86E+06 - - - 0.4847 - 3.497 0.615 - 349.3 1 1 0 0.0011 23 0 0 0 5.40E+07 3.78E+07 - - - 8.3332 1 221125_WJC_METTL3_EV_vs_WT_F06.20291.20291.3 0.0821 19/68 R.RAEDGSVIDYELIDQDAR.D "sp|P07355|ANXA2_HUMAN,tr|H0YL33|H0YL33_HUMAN,tr|H0YMU9|H0YMU9_HUMAN,tr|H0YNA0|H0YNA0_HUMAN,tr|H0YM50|H0YM50_HUMAN,tr|H0YMD0|H0YMD0_HUMAN,tr|H0YMW4|H0YMW4_HUMAN,tr|H0YN42|H0YN42_HUMAN,tr|H0YN28|H0YN28_HUMAN,tr|H0YNP5|H0YNP5_HUMAN" 10 2063.976 1.84 87955 20291 3 2063.967883 688.9993 Annexin A2 OS=Homo sapiens OX=9606 GN=ANXA2 PE=1 SV=2 3.96 3193.9 - 1.69E+06 - - - -3.9216 - 3.892 0.612 - 542.2 1 2 0 -0.0081 18 0 0 0 1.33E+07 7.19E+06 - - - 8.7448 1 221125_WJC_METTL3_EV_vs_WT_F06.20292.20292.3 1.92E-06 17/56 R.SDPTSYAGYIEDLK[136.11]K[136.11].F "sp|P54709|AT1B3_HUMAN,tr|C9JA36|C9JA36_HUMAN,tr|C9JXZ1|C9JXZ1_HUMAN" 3 1701.8432 1.06 87956 20292 3 1701.844394 568.2884 Sodium\potassium-transporting ATPase subunit beta-3 OS=Homo sapiens OX=9606 GN=ATP1B3 PE=1 SV=1 4.56 3194.1 - 1.40E+06 - - - 0.6828 - 3.371 0.575 - 314.8 1 2 0 0.0012 15 0 0 0 5.48E+07 5.18E+07 - - - 8.1213 1 221125_WJC_METTL3_EV_vs_WT_F06.20298.20298.4 1.18E-11 22/132 K.FKPVIGTWDC[160.03]DTC[160.03]LVQNKPEAIK.C sp|P49790|NU153_HUMAN 1 2718.3509 1.47 87960 20298 4 2718.353451 680.595 Nuclear pore complex protein Nup153 OS=Homo sapiens OX=9606 GN=NUP153 PE=1 SV=2 6.11 3194.9 - 2.69E+06 - - - 0.9223 - 3.705 0.659 - 395.4 1 2 0 0.0025 23 0 0 0 9.02E+07 6.13E+07 - - - 5.3856 1 221125_WJC_METTL3_EV_vs_WT_F06.20299.20299.3 7.80E-12 26/108 R.AAASLAAVSGTAAASLGSAQPTDLGAHK.R sp|Q7Z5L9|I2BP2_HUMAN 1 2493.2823 1.5 87961 20299 3 2493.286152 832.1014 Interferon regulatory factor 2-binding protein 2 OS=Homo sapiens OX=9606 GN=IRF2BP2 PE=1 SV=2 6.79 3194.9 - 2.83E+06 - - - 1.5329 - 4.381 0.581 - 546.5 1 2 0 0.0038 28 0 0 0 2.80E+08 1.87E+08 - - - 8.4152 1 221125_WJC_METTL3_EV_vs_WT_F06.20301.20301.4 9.83E-14 24/132 K.FK[136.11]PVIGTWDC[160.03]DTC[160.03]LVQNK[136.11]PEAIK[136.11].C sp|P49790|NU153_HUMAN 1 2742.3935 1.47 87963 20301 4 2742.392864 686.6057 Nuclear pore complex protein Nup153 OS=Homo sapiens OX=9606 GN=NUP153 PE=1 SV=2 6.11 3195.1 - 1.43E+06 - - - -0.248 - 4.438 0.643 - 503.2 1 2 0 -0.0007 23 0 0 0 9.02E+07 6.13E+07 - - - 5.3053 1 221125_WJC_METTL3_EV_vs_WT_F06.20302.20302.3 7.64E-12 21/80 K.SVSPQNSDSSGFADVNGWHLR[166.11].F "sp|Q9UKB3|DJC12_HUMAN,tr|S4R3E2|S4R3E2_HUMAN" 2 2269.0387 2.91 87964 20302 3 2269.043125 757.3535 DnaJ homolog subfamily C member 12 OS=Homo sapiens OX=9606 GN=DNAJC12 PE=1 SV=1 5.19 3195.3 - 1.12E+06 - - - 1.9317 - 3.905 0.631 - 539.8 1 2 0 0.0044 21 0 0 0 3.74E+07 1.29E+07 - - - 8.8398 1 221125_WJC_METTL3_EV_vs_WT_F06.20304.20304.4 0.000563 19/90 K.DDPSKPVHLTAFLGYK.A "sp|P39023|RL3_HUMAN,tr|H7C3M2|H7C3M2_HUMAN,tr|F8WCR1|F8WCR1_HUMAN,tr|H7C422|H7C422_HUMAN" 4 1786.9254 1.02 87966 20304 4 1786.926231 447.7386 60S ribosomal protein L3 OS=Homo sapiens OX=9606 GN=RPL3 PE=1 SV=2 6.75 3195.5 - 767131 - - - 0.4729 - 3.518 0.593 - 267.8 1 2 0 0.0008 16 0 0 0 4.84E+07 4.76E+07 - - - 4.8303 1 221125_WJC_METTL3_EV_vs_WT_F06.20306.20306.4 4.12E-09 20/90 K.DDPSK[136.11]PVHLTAFLGYK[136.11].A "sp|P39023|RL3_HUMAN,tr|H7C3M2|H7C3M2_HUMAN,tr|F8WCR1|F8WCR1_HUMAN,tr|H7C422|H7C422_HUMAN" 4 1802.9538 1.02 87968 20306 4 1802.951458 451.7457 60S ribosomal protein L3 OS=Homo sapiens OX=9606 GN=RPL3 PE=1 SV=2 6.75 3195.8 - 724710 - - - -1.2912 - 3.566 0.573 - 285.2 1 2 0 -0.0023 16 0 0 0 4.84E+07 4.76E+07 - - - 4.6606 0.9995 221125_WJC_METTL3_EV_vs_WT_F06.20311.20311.3 0.000361 13/48 R.EK[136.11]VEVQLPELFHK[136.11].L "sp|Q13303|KCAB2_HUMAN,tr|A0A590UJJ4|A0A590UJJ4_HUMAN,tr|A0A5F9UN28|A0A5F9UN28_HUMAN,tr|A0A590UJB6|A0A590UJB6_HUMAN" 4 1610.9003 1.61 87972 20311 3 1610.90001 537.974 Voltage-gated potassium channel subunit beta-2 OS=Homo sapiens OX=9606 GN=KCNAB2 PE=1 SV=2 5.5 3196.4 - 1.15E+06 - - - -0.1757 - 2.499 0.363 - 247.7 1 2 1 -0.0003 13 0 0 0 1.22E+08 7.58E+07 - - - 5.0703 0.9976 221125_WJC_METTL3_EV_vs_WT_F06.20315.20315.4 0.0377 17/156 K.AGTIGQTHLLGHQLDSFGTVPESGSLK[136.11].S sp|Q7L804|RFIP2_HUMAN 1 2757.4177 2.45 87974 20315 4 2757.415039 690.3617 Rab11 family-interacting protein 2 OS=Homo sapiens OX=9606 GN=RAB11FIP2 PE=1 SV=1 6 3196.9 - 788145 - - - -0.9679 - 2.661 0.248 - 99.5 1 2 0 -0.0027 27 0 0 0 3.63E+07 1.48E+07 - - - 1.6901 1 221125_WJC_METTL3_EV_vs_WT_F06.20316.20316.3 4.05E-15 26/120 R.LPGPTGSVVSTGTSFSSSSPGLASAGAAEGK.Q sp|Q7Z434|MAVS_HUMAN 1 2763.3563 0.96 87975 20316 3 2763.356749 922.126 Mitochondrial antiviral-signaling protein OS=Homo sapiens OX=9606 GN=MAVS PE=1 SV=2 6 3197 - 654739 - - - 0.1686 - 4.718 0.647 - 466.2 1 2 0 0.0005 31 0 0 0 6.26E+06 6.50E+06 - - - 9.3225 1 221125_WJC_METTL3_EV_vs_WT_F06.20317.20317.3 5.25E-10 21/60 K.DDPSKPVHLTAFLGYK.A "sp|P39023|RL3_HUMAN,tr|H7C3M2|H7C3M2_HUMAN,tr|F8WCR1|F8WCR1_HUMAN,tr|H7C422|H7C422_HUMAN" 4 1786.9254 1.26 87976 20317 3 1786.926494 596.6491 60S ribosomal protein L3 OS=Homo sapiens OX=9606 GN=RPL3 PE=1 SV=2 6.75 3197.1 - 2.08E+06 - - - 0.6201 - 4.031 0.62 - 639.9 1 2 0 0.0011 16 0 0 0 8.38E+07 6.67E+07 - - - 9.0289 1 221125_WJC_METTL3_EV_vs_WT_F06.20319.20319.3 3.01E-13 30/120 R.LPGPTGSVVSTGTSFSSSSPGLASAGAAEGK[136.11].Q sp|Q7Z434|MAVS_HUMAN 1 2771.3705 0.96 87978 20319 3 2771.368376 924.7974 Mitochondrial antiviral-signaling protein OS=Homo sapiens OX=9606 GN=MAVS PE=1 SV=2 6 3197.4 - 768864 - - - -0.7603 - 5.393 0.678 - 757.9 1 2 0 -0.0021 31 0 0 0 6.26E+06 6.50E+06 - - - 9.9753 1 221125_WJC_METTL3_EV_vs_WT_F06.20324.20324.3 1.86E-11 Oct-88 K.FKPVIGTWDC[160.03]DTC[160.03]LVQNKPEAIK.C sp|P49790|NU153_HUMAN 1 2718.3509 2.12 87981 20324 3 2718.350799 907.1243 Nuclear pore complex protein Nup153 OS=Homo sapiens OX=9606 GN=NUP153 PE=1 SV=2 6.11 3198 - 553406 - - - -0.0533 - 2.867 0.654 - 66.6 1 2 0 -0.0001 23 0 0 0 8.69E+06 4.10E+06 - - - 8.3023 1 221125_WJC_METTL3_EV_vs_WT_F06.20327.20327.4 4.55E-10 21/162 R.AAASLAAVSGTAAASLGSAQPTDLGAHK.R sp|Q7Z5L9|I2BP2_HUMAN 1 2493.2823 1.41 87983 20327 4 2493.28696 624.3279 Interferon regulatory factor 2-binding protein 2 OS=Homo sapiens OX=9606 GN=IRF2BP2 PE=1 SV=2 6.79 3198.3 - 8.55E+06 - - - 1.857 - 3.805 0.55 - 162.1 1 2 0 0.0046 28 0 0 0 1.44E+08 1.02E+08 - - - 4.4268 1 221125_WJC_METTL3_EV_vs_WT_F06.20329.20329.3 6.64E-08 16/68 R.GK[136.11]PPPLLPSVLGPAGGDR[166.11].E "sp|Q8IY67|RAVR1_HUMAN,tr|E9PAU2|E9PAU2_HUMAN,tr|A0A087WZ13|A0A087WZ13_HUMAN" 3 1744.9955 1.07 87985 20329 3 1744.99736 582.6724 Ribonucleoprotein PTB-binding 1 OS=Homo sapiens OX=9606 GN=RAVER1 PE=1 SV=1 8.75 3198.5 - 599372 - - - 1.0808 - 2.959 0.555 - 266.2 1 2 0 0.0019 18 0 0 0 1.41E+07 1.31E+07 - - - 7.4286 1 221125_WJC_METTL3_EV_vs_WT_F06.20330.20330.3 1.51E-11 23/100 R.IVEDAPPIDLQAEAQHASGEVEEPPR.Y "sp|P30876|RPB2_HUMAN,tr|C9J2Y9|C9J2Y9_HUMAN" 2 2796.3566 1.23 87986 20330 3 2796.360411 933.1261 DNA-directed RNA polymerase II subunit RPB2 OS=Homo sapiens OX=9606 GN=POLR2B PE=1 SV=1 4 3198.6 - 525438 - - - 1.3568 - 3.774 0.675 - 383.4 1 2 0 0.0038 26 0 0 0 2.72E+07 2.22E+07 - - - 9.1201 1 221125_WJC_METTL3_EV_vs_WT_F06.20333.20333.3 7.71E-07 21/88 K.IGSNNSTTPTVPLK[136.11]PPPPLTLGK[136.11].T "sp|Q96CB8|INT12_HUMAN,tr|A0A087WXN4|A0A087WXN4_HUMAN" 2 2344.3337 1.07 87987 20333 3 2344.335272 782.4518 Integrator complex subunit 12 OS=Homo sapiens OX=9606 GN=INTS12 PE=1 SV=1 10 3199.1 - 1.37E+06 - - - 0.6718 - 3.712 0.598 - 309.3 1 2 0 0.0016 23 0 0 0 9.23E+07 8.59E+07 - - - 8.2835 1 221125_WJC_METTL3_EV_vs_WT_F06.20334.20334.3 5.60E-14 34/96 R.NQVTC[160.03]LSVSTDGSVLLSGSHDETVR.L "sp|Q9BV38|WDR18_HUMAN,tr|U3KQC1|U3KQC1_HUMAN,tr|U3KQK3|U3KQK3_HUMAN,tr|A0A0A0MQU0|A0A0A0MQU0_HUMAN,tr|K7EIR0|K7EIR0_HUMAN" 5 2660.2712 0.97 87988 20334 3 2660.271856 887.7643 WD repeat-containing protein 18 OS=Homo sapiens OX=9606 GN=WDR18 PE=1 SV=2 4.54 3199.2 - 1.27E+06 - - - 0.2567 - 5.867 0.709 - 1024.6 1 2 0 0.0007 25 0 0 0 5.87E+07 6.06E+07 - - - 10.5151 1 221125_WJC_METTL3_EV_vs_WT_F06.20335.20335.3 3.12E-13 24/96 R.MSGDLSSNVTVSVTSSTISSNVASK.A sp|P35908|K22E_HUMAN 1 2457.1905 2340.86 87989 20335 3 2457.193398 820.0708 "Keratin, type II cytoskeletal 2 epidermal OS=Homo sapiens OX=9606 GN=KRT2 PE=1 SV=2" 5.59 3199.3 - 841913 - - - 1.1945 - 4.415 0.686 - 570.7 1 2 0 0.0029 25 0 0 0 7.65E+08 3.27E+05 - - - 9.6039 1 221125_WJC_METTL3_EV_vs_WT_F06.20342.20342.3 3.66E-08 25/88 K.IGSNNSTTPTVPLKPPPPLTLGK.T "sp|Q96CB8|INT12_HUMAN,tr|A0A087WXN4|A0A087WXN4_HUMAN" 2 2328.3053 1.11 87994 20342 3 2328.3084 777.109 Integrator complex subunit 12 OS=Homo sapiens OX=9606 GN=INTS12 PE=1 SV=1 10 3200.2 - 1.88E+06 - - - 1.3327 - 4.051 0.584 - 418.4 1 2 0 0.0031 23 0 0 0 9.23E+07 8.33E+07 - - - 8.3321 0.9998 221125_WJC_METTL3_EV_vs_WT_F06.20344.20344.4 1.91E-05 14/144 R.LVSGMQHPGSAGGVYETTQHFIDIK.E sp|P49257|LMAN1_HUMAN 1 2671.3064 1.47 87996 20344 4 2671.314551 668.8339 Protein ERGIC-53 OS=Homo sapiens OX=9606 GN=LMAN1 PE=1 SV=2 5.99 3200.4 - 1.13E+06 - - - 3.0378 - 2.295 0.457 - 57.2 1 2 0 0.0081 25 0 0 0 5.16E+07 3.51E+07 - - - 3.4658 0.9999 221125_WJC_METTL3_EV_vs_WT_F06.20345.20345.3 6.49E-07 15/88 K.EIETYHNLLEGGQEDFESSGAGK.L "sp|P35527|K1C9_HUMAN,tr|K7EQQ3|K7EQQ3_HUMAN" 2 2509.1245 10.76 87997 20345 3 2509.117656 837.3821 "Keratin, type I cytoskeletal 9 OS=Homo sapiens OX=9606 GN=KRT9 PE=1 SV=3" 4.14 3200.6 - 997848 - - - -2.7245 - 2.776 0.537 - 255.8 1 2 0 -0.0068 23 0 0 0 8.58E+06 7.98E+05 - - - 6.9204 1 221125_WJC_METTL3_EV_vs_WT_F06.20346.20346.3 1.70E-09 15/76 R.GGETPEGLATSVVHYGAGAK.E sp|Q9ULL5|PRR12_HUMAN 1 1899.9327 3.6 87998 20346 3 1899.93731 634.3182 Proline-rich protein 12 OS=Homo sapiens OX=9606 GN=PRR12 PE=1 SV=3 5.4 3200.7 - 711490 - - - 2.4496 - 3.486 0.547 - 271.5 1 2 0 0.0047 20 0 0 0 3.75E+07 1.04E+07 - - - 7.6667 1 221125_WJC_METTL3_EV_vs_WT_F06.20348.20348.3 3.12E-06 Oct-88 K.FK[136.11]PVIGTWDC[160.03]DTC[160.03]LVQNK[136.11]PEAIK[136.11].C sp|P49790|NU153_HUMAN 1 2742.3935 2.12 88000 20348 3 2742.390379 915.1385 Nuclear pore complex protein Nup153 OS=Homo sapiens OX=9606 GN=NUP153 PE=1 SV=2 6.11 3201 - 373686 - - - -1.1541 - 2.181 0.542 - 94.1 1 2 0 -0.0032 23 0 0 0 8.69E+06 4.10E+06 - - - 6.4112 0.9999 221125_WJC_METTL3_EV_vs_WT_F06.20361.20361.4 1.22E-07 16/144 R.LVSGMQHPGSAGGVYETTQHFIDIK[136.11].E sp|P49257|LMAN1_HUMAN 1 2679.3206 1.48 88009 20361 4 2679.326431 670.8374 Protein ERGIC-53 OS=Homo sapiens OX=9606 GN=LMAN1 PE=1 SV=2 5.99 3202.6 - 2.72E+06 - - - 2.1629 - 2.659 0.479 - 72.9 1 2 0 0.0058 25 0 0 0 5.16E+07 3.50E+07 - - - 3.7047 1 221125_WJC_METTL3_EV_vs_WT_F06.20362.20362.3 4.27E-12 20/72 R.QFLLQQASGLSSPGNNDSK.Q "sp|Q8IVH2|FOXP4_HUMAN,tr|B7ZBM3|B7ZBM3_HUMAN,tr|A2A312|A2A312_HUMAN" 3 1989.9756 17.56 88010 20362 3 1989.977622 664.3325 Forkhead box protein P4 OS=Homo sapiens OX=9606 GN=FOXP4 PE=1 SV=1 5.84 3202.7 - 1.09E+06 - - - 1.0246 - 4.044 0.595 - 461.3 1 2 0 0.002 19 0 0 0 2.08E+07 1.18E+06 - - - 8.6058 1 221125_WJC_METTL3_EV_vs_WT_F06.20363.20363.2 9.64E-13 23/48 R.MSGDLSSNVTVSVTSSTISSNVASK.A sp|P35908|K22E_HUMAN 1 2457.1905 999 88011 20363 2 2457.19148 1229.6025 "Keratin, type II cytoskeletal 2 epidermal OS=Homo sapiens OX=9606 GN=KRT2 PE=1 SV=2" 5.59 3202.8 - 591333 - - - 0.4139 - 4.733 0.727 - 1005.7 1 2 0 0.001 25 0 0 0 8.78E+07 0.00E+00 - - - 8.2323 0.9997 221125_WJC_METTL3_EV_vs_WT_F06.20364.20364.3 9.77E-10 14/96 R.LVSGMQHPGSAGGVYETTQHFIDIK[136.11].E sp|P49257|LMAN1_HUMAN 1 2679.3206 0.57 88012 20364 3 2680.323497 894.1142 Protein ERGIC-53 OS=Homo sapiens OX=9606 GN=LMAN1 PE=1 SV=2 5.99 3203 - 454688 - - - 374.2967 - 3.114 0.619 - 140.7 1 2 0 1.0029 25 0 0 0 4.80E+06 8.35E+06 - - - 7.7768 1 221125_WJC_METTL3_EV_vs_WT_F06.20365.20365.2 8.20E-10 13/36 R.QFLLQQASGLSSPGNNDSK.Q "sp|Q8IVH2|FOXP4_HUMAN,tr|B7ZBM3|B7ZBM3_HUMAN,tr|A2A312|A2A312_HUMAN" 3 1989.9756 57.83 88013 20365 2 1989.976897 995.9951 Forkhead box protein P4 OS=Homo sapiens OX=9606 GN=FOXP4 PE=1 SV=1 5.84 3203.1 - 424377 - - - 0.6603 - 3.059 0.712 - 364.7 1 2 0 0.0013 19 0 0 0 7.59E+06 1.31E+05 - - - 7.0483 1 221125_WJC_METTL3_EV_vs_WT_F06.20371.20371.3 1.40E-06 24/100 R.IVEDAPPIDLQAEAQHASGEVEEPPR[166.11].Y "sp|P30876|RPB2_HUMAN,tr|C9J2Y9|C9J2Y9_HUMAN" 2 2806.3649 1.23 88017 20371 3 2806.370007 936.4622 DNA-directed RNA polymerase II subunit RPB2 OS=Homo sapiens OX=9606 GN=POLR2B PE=1 SV=1 4 3203.9 - 581412 - - - 1.8244 - 4.47 0.691 - 383.4 1 2 0 0.0051 26 0 0 0 2.72E+07 2.22E+07 - - - 9.6875 0.977 221125_WJC_METTL3_EV_vs_WT_F06.20373.20373.4 1.30E-05 18/114 K.YNRLDIIETNVKPSILEAQK.N "sp|O95163|ELP1_HUMAN,tr|A0A6Q8PFB7|A0A6Q8PFB7_HUMAN,tr|A0A6Q8PHI5|A0A6Q8PHI5_HUMAN,tr|A0A6Q8PGW3|A0A6Q8PGW3_HUMAN,tr|A0A6Q8PG86|A0A6Q8PG86_HUMAN,tr|A0A6Q8PEX6|A0A6Q8PEX6_HUMAN,tr|F5H2T0|F5H2T0_HUMAN,tr|A0A6Q8PHF4|A0A6Q8PHF4_HUMAN" 8 2343.2798 0.4 88019 20373 4 2343.286353 586.8272 Elongator complex protein 1 OS=Homo sapiens OX=9606 GN=ELP1 PE=1 SV=3 6.18 3204.2 - 616092 - - - 2.7918 - 2.914 0.247 - 194 1 2 1 0.0065 20 0 0 0 4.09E+06 1.01E+07 - - - 1.7316 1 221125_WJC_METTL3_EV_vs_WT_F06.20385.20385.3 3.00E-10 15/80 R.VIPSFMC[160.03]QAGDFTNHNGTGGK[136.11].S "sp|P30405|PPIF_HUMAN,tr|H0Y548|H0Y548_HUMAN,tr|R4GN99|R4GN99_HUMAN" 3 2245.0136 1.69 88027 20385 3 2245.019701 749.3451 "Peptidyl-prolyl cis-trans isomerase F, mitochondrial OS=Homo sapiens OX=9606 GN=PPIF PE=1 SV=1" 6.71 3205.7 - 708023 - - - 2.7301 - 3.315 0.603 - 154.5 1 2 0 0.0061 21 0 0 0 1.84E+07 1.09E+07 - - - 8.1344 1 221125_WJC_METTL3_EV_vs_WT_F06.20386.20386.3 2.24E-10 20/76 K.GILGYTEHQVVSSDFNSDTH.S "sp|P04406|G3P_HUMAN,tr|E7EUT5|E7EUT5_HUMAN" 2 2204.9974 - 88028 20386 3 2205.004233 736.0064 Glyceraldehyde-3-phosphate dehydrogenase OS=Homo sapiens OX=9606 GN=GAPDH PE=1 SV=3 4.52 3205.8 - 1.62E+06 - - - 3.0803 - 3.58 0.653 - 605.8 1 1 0 0.0068 20 0 0 0 - - - - - 8.9125 0.9977 221125_WJC_METTL3_EV_vs_WT_F06.20388.20388.3 9.66E-08 14/48 S.SHNLQSIFNIGSR[166.11].G "sp|P43243|MATR3_HUMAN,tr|A8MXP9|A8MXP9_HUMAN,tr|D6R991|D6R991_HUMAN,tr|D6REK4|D6REK4_HUMAN,tr|A0A0R4J2E8|A0A0R4J2E8_HUMAN,tr|D6RCM3|D6RCM3_HUMAN,tr|D6R8Z5|D6R8Z5_HUMAN,tr|D6REM6|D6REM6_HUMAN" 8 1481.7614 1.29 88030 20388 3 1481.76393 494.9278 Matrin-3 OS=Homo sapiens OX=9606 GN=MATR3 PE=1 SV=2 9.49 3206 - 995637 - - - 1.6771 - 2.904 0.559 - 229.1 1 1 0 0.0025 13 0 0 0 1.38E+08 1.07E+08 - - - 7.6621 0.9999 221125_WJC_METTL3_EV_vs_WT_F06.20389.20389.4 3.85E-05 13/78 R.VHFEESSKLEDLLR.K "sp|P12956|XRCC6_HUMAN,tr|B1AHC9|B1AHC9_HUMAN" 2 1700.8734 1.12 88031 20389 4 1700.875341 426.2256 X-ray repair cross-complementing protein 6 OS=Homo sapiens OX=9606 GN=XRCC6 PE=1 SV=2 4.83 3206.1 - 684935 - - - 1.1706 - 2.697 0.537 - 178.9 1 2 1 0.002 14 0 0 0 1.88E+07 1.68E+07 - - - 4.2606 0.9999 221125_WJC_METTL3_EV_vs_WT_F06.20390.20390.4 7.46E-05 15/78 R.VHFEESSK[136.11]LEDLLR[166.11].K "sp|P12956|XRCC6_HUMAN,tr|B1AHC9|B1AHC9_HUMAN" 2 1718.8958 1.12 88032 20390 4 1718.897146 430.7312 X-ray repair cross-complementing protein 6 OS=Homo sapiens OX=9606 GN=XRCC6 PE=1 SV=2 4.83 3206.2 - 660797 - - - 0.7714 - 2.736 0.508 - 261 1 2 1 0.0013 14 0 0 0 1.88E+07 1.68E+07 - - - 4.0136 0.9986 221125_WJC_METTL3_EV_vs_WT_F06.20394.20394.3 0.000704 17/48 S.SHNLQSIFNIGSR.G "sp|P43243|MATR3_HUMAN,tr|A8MXP9|A8MXP9_HUMAN,tr|D6R991|D6R991_HUMAN,tr|D6REK4|D6REK4_HUMAN,tr|A0A0R4J2E8|A0A0R4J2E8_HUMAN,tr|D6RCM3|D6RCM3_HUMAN,tr|D6R8Z5|D6R8Z5_HUMAN,tr|D6REM6|D6REM6_HUMAN" 8 1471.7532 1.29 88034 20394 3 1471.753803 491.5917 Matrin-3 OS=Homo sapiens OX=9606 GN=MATR3 PE=1 SV=2 9.49 3206.8 - 2.28E+06 - - - 0.4267 - 3.038 0.553 - 535.3 1 1 0 0.0006 13 0 0 0 1.38E+08 1.07E+08 - - - 7.718 1 221125_WJC_METTL3_EV_vs_WT_F06.20395.20395.3 3.41E-10 18/52 R.VHFEESSK[136.11]LEDLLR[166.11].K "sp|P12956|XRCC6_HUMAN,tr|B1AHC9|B1AHC9_HUMAN" 2 1718.8958 1.09 88035 20395 3 1718.901137 573.9725 X-ray repair cross-complementing protein 6 OS=Homo sapiens OX=9606 GN=XRCC6 PE=1 SV=2 4.83 3206.9 - 1.26E+06 - - - 3.0933 - 3.411 0.605 - 529.1 1 2 1 0.0053 14 0 0 0 2.82E+07 2.59E+07 - - - 8.5445 1 221125_WJC_METTL3_EV_vs_WT_F06.20396.20396.3 2.64E-12 23/52 R.VHFEESSKLEDLLR.K "sp|P12956|XRCC6_HUMAN,tr|B1AHC9|B1AHC9_HUMAN" 2 1700.8734 1.09 88036 20396 3 1700.878355 567.9651 X-ray repair cross-complementing protein 6 OS=Homo sapiens OX=9606 GN=XRCC6 PE=1 SV=2 4.83 3207 - 1.18E+06 - - - 2.9426 - 3.878 0.662 - 897.4 1 2 1 0.005 14 0 0 0 2.82E+07 2.59E+07 - - - 9.5211 1 221125_WJC_METTL3_EV_vs_WT_F06.20398.20398.3 7.40E-08 13/60 K.VELAQLQEEWNEHNAK[136.11].L sp|Q9H307|PININ_HUMAN 1 1944.9421 1.63 88038 20398 3 1944.944151 649.3213 Pinin OS=Homo sapiens OX=9606 GN=PNN PE=1 SV=5 4.48 3207.2 - 751562 - - - 1.052 - 2.684 0.55 - 181.5 1 2 0 0.002 16 0 0 0 1.92E+07 1.18E+07 - - - 7.2047 0.9995 221125_WJC_METTL3_EV_vs_WT_F06.20399.20399.4 4.96E-05 16/78 R.YQTLELEK[136.11]EFHFNR[166.11].Y "sp|Q00444|HXC5_HUMAN,sp|P09630|HXC6_HUMAN,sp|P31268|HXA7_HUMAN,sp|P09067|HXB5_HUMAN,sp|P20719|HXA5_HUMAN,sp|P31267|HXA6_HUMAN,tr|V9GYH0|V9GYH0_HUMAN" 7 1870.9333 2.13 88039 20399 4 1870.936158 468.7406 Homeobox protein Hox-C5 OS=Homo sapiens OX=9606 GN=HOXC5 PE=1 SV=1 5.5 3207.4 - 559150 - - - 1.5447 - 2.662 0.415 - 167 1 2 1 0.0029 14 0 0 0 1.55E+07 7.26E+06 - - - 3.1937 1 221125_WJC_METTL3_EV_vs_WT_F06.20400.20400.3 1.43E-06 14/104 R.IGQELLFPPQENVQDAGAPGGHTQNLR[166.11].C sp|Q5JSZ5|PRC2B_HUMAN 1 2895.4503 1.88 88040 20400 3 2895.451021 966.1574 Protein PRRC2B OS=Homo sapiens OX=9606 GN=PRRC2B PE=1 SV=2 4.65 3207.5 - 400428 - - - 0.2528 - 3.006 0.605 - 89.1 1 2 0 0.0007 27 0 0 0 9.19E+06 4.90E+06 - - - 7.8171 0.997 221125_WJC_METTL3_EV_vs_WT_F06.20401.20401.4 0.0215 13/102 K.YVATLGVEVHPLVFHTNR[166.11].G "sp|P62826|RAN_HUMAN,tr|H0YFC6|H0YFC6_HUMAN,tr|B5MDF5|B5MDF5_HUMAN,tr|J3KQE5|J3KQE5_HUMAN,tr|F5H018|F5H018_HUMAN" 5 2061.1035 0.59 88041 20401 4 2061.108776 516.2832 GTP-binding nuclear protein Ran OS=Homo sapiens OX=9606 GN=RAN PE=1 SV=3 6.92 3207.6 - 353003 - - - 2.5525 - 2.512 0.276 - 95.2 1 2 0 0.0053 18 0 0 0 4.62E+06 7.79E+06 - - - 1.9424 1 221125_WJC_METTL3_EV_vs_WT_F06.20405.20405.3 4.99E-12 25/72 K.LRENSASQISQLEQQLSAK.N "sp|Q13948|CASP_HUMAN,sp|P39880|CUX1_HUMAN,tr|A0A2R8Y852|A0A2R8Y852_HUMAN,tr|A0A2R8YDI1|A0A2R8YDI1_HUMAN" 4 2129.1077 1.33 88043 20405 3 2129.113769 710.7098 Protein CASP OS=Homo sapiens OX=9606 GN=CUX1 PE=1 SV=2 6.14 3208.1 - 1.25E+06 - - - 2.8693 - 4.73 0.621 - 742.4 1 2 1 0.0061 19 0 0 0 1.28E+08 9.64E+07 - - - 9.2795 1 221125_WJC_METTL3_EV_vs_WT_F06.20407.20407.3 0.000467 15/64 R.IINEPTAAAIAYGLDKK.G "sp|P54652|HSP72_HUMAN,sp|P11142|HSP7C_HUMAN,tr|E9PKE3|E9PKE3_HUMAN,tr|E9PN89|E9PN89_HUMAN,tr|E9PI65|E9PI65_HUMAN" 5 1786.9829 0.25 88045 20407 3 1786.986388 596.6682 Heat shock-related 70 kDa protein 2 OS=Homo sapiens OX=9606 GN=HSPA2 PE=1 SV=1 6.07 3208.3 - 1.68E+06 - - - 1.9519 - 3.349 0.455 - 234.2 1 2 0 0.0035 17 0 0 0 2.29E+07 9.27E+07 - - - 6.6653 1 221125_WJC_METTL3_EV_vs_WT_F06.20409.20409.3 7.34E-09 16/72 R.K[136.11]EGGGGISC[160.03]VLQDGC[160.03]VFEK[136.11].A sp|P36551|HEM6_HUMAN 1 2054.9736 1.09 88047 20409 3 2054.976507 685.9985 "Oxygen-dependent coproporphyrinogen-III oxidase, mitochondrial OS=Homo sapiens OX=9606 GN=CPOX PE=1 SV=3" 4.68 3208.5 - 992082 - - - 1.4088 - 3.446 0.596 - 468 1 2 0 0.0029 19 0 0 0 4.42E+07 4.06E+07 - - - 8.2236 0.9999 221125_WJC_METTL3_EV_vs_WT_F06.20412.20412.4 1.27E-05 14/102 K.YVATLGVEVHPLVFHTNR.G "sp|P62826|RAN_HUMAN,tr|H0YFC6|H0YFC6_HUMAN,tr|B5MDF5|B5MDF5_HUMAN,tr|J3KQE5|J3KQE5_HUMAN,tr|F5H018|F5H018_HUMAN" 5 2051.0952 0.59 88050 20412 4 2051.09628 513.7811 GTP-binding nuclear protein Ran OS=Homo sapiens OX=9606 GN=RAN PE=1 SV=3 6.92 3208.9 - 412564 - - - 0.5046 - 2.723 0.406 - 112.7 1 2 0 0.001 18 0 0 0 4.62E+06 7.79E+06 - - - 3.1027 1 221125_WJC_METTL3_EV_vs_WT_F06.20417.20417.3 6.51E-06 14/76 K.SYNPFDDDGEDEGAR[166.11]PAPWR[166.11].D sp|O95721|SNP29_HUMAN 1 2312.9837 2.01 88053 20417 3 2312.983489 772.0019 Synaptosomal-associated protein 29 OS=Homo sapiens OX=9606 GN=SNAP29 PE=1 SV=1 3.96 3209.4 - 954841 - - - -0.1098 - 2.515 0.663 - 184.2 1 2 0 -0.0003 20 0 0 0 3.07E+07 1.53E+07 - - - 8.1692 1 221125_WJC_METTL3_EV_vs_WT_F06.20419.20419.4 1.03E-11 22/144 K.AALDC[160.03]STSHLDEFYSDPHAVAGALK.S sp|Q68EM7|RHG17_HUMAN 1 2674.2333 1.53 88055 20419 4 2674.235377 669.5656 Rho GTPase-activating protein 17 OS=Homo sapiens OX=9606 GN=ARHGAP17 PE=1 SV=1 4.64 3209.6 - 3.65E+06 - - - 0.7651 - 3.331 0.69 - 214.1 1 2 0 0.002 25 0 0 0 5.21E+07 3.41E+07 - - - 5.614 1 221125_WJC_METTL3_EV_vs_WT_F06.20420.20420.3 3.49E-09 26/72 K.LR[166.11]ENSASQISQLEQQLSAK[136.11].N "sp|Q13948|CASP_HUMAN,sp|P39880|CUX1_HUMAN,tr|A0A2R8Y852|A0A2R8Y852_HUMAN,tr|A0A2R8YDI1|A0A2R8YDI1_HUMAN" 4 2147.1301 1.33 88056 20420 3 2147.13403 716.7173 Protein CASP OS=Homo sapiens OX=9606 GN=CUX1 PE=1 SV=2 6.14 3209.7 - 2.38E+06 - - - 1.8164 - 4.73 0.651 - 911.8 1 2 1 0.0039 19 0 0 0 1.28E+08 9.64E+07 - - - 9.6146 1 221125_WJC_METTL3_EV_vs_WT_F06.20429.20429.3 3.56E-12 18/64 R.K[136.11]DDPVTNLNNAFEVAEK[136.11].Y "sp|O43707|ACTN4_HUMAN,tr|F5GXS2|F5GXS2_HUMAN,tr|H7C144|H7C144_HUMAN" 3 1918.9607 1.2 88063 20429 3 1918.96149 640.6609 Alpha-actinin-4 OS=Homo sapiens OX=9606 GN=ACTN4 PE=1 SV=2 4.32 3210.8 - 1.26E+06 - - - 0.4007 - 3.682 0.563 - 641.2 1 2 0 0.0008 17 0 0 0 5.54E+07 4.61E+07 - - - 8.1096 1 221125_WJC_METTL3_EV_vs_WT_F06.20432.20432.3 1.10E-17 18/76 R.C[160.03]EHDGVMTGANGEVSFINIK[136.11].T sp|O15371|EIF3D_HUMAN 1 2185.0023 1.01 88066 20432 3 2184.998581 729.3414 Eukaryotic translation initiation factor 3 subunit D OS=Homo sapiens OX=9606 GN=EIF3D PE=1 SV=1 4.65 3211.2 - 749592 - - - -1.7199 - 3.762 0.74 - 435.5 1 2 0 -0.0038 20 0 0 0 1.36E+07 1.34E+07 - - - 10.0036 1 221125_WJC_METTL3_EV_vs_WT_F06.20437.20437.3 0.000114 23/76 R.RALQAAIQQLAEAQPEATAK.N sp|Q92616|GCN1_HUMAN 1 2107.1386 1.04 88071 20437 3 2107.140292 703.3868 eIF-2-alpha kinase activator GCN1 OS=Homo sapiens OX=9606 GN=GCN1 PE=1 SV=6 6.14 3211.9 - 320042 - - - 0.8191 - 4.171 0.495 - 319.4 1 2 0 0.0017 20 0 0 0 3.79E+06 3.66E+06 - - - 7.523 1 221125_WJC_METTL3_EV_vs_WT_F06.20442.20442.3 1.70E-12 28/88 R.ALQSGQC[160.03]AGAALDVFTEEPPRDR.A "sp|O43175|SERA_HUMAN,tr|A0A286YF78|A0A286YF78_HUMAN,tr|A0A2C9F2M7|A0A2C9F2M7_HUMAN,tr|A0A286YF22|A0A286YF22_HUMAN,tr|A0A286YFL2|A0A286YFL2_HUMAN,tr|A0A286YFA2|A0A286YFA2_HUMAN" 6 2487.1812 2.08 88074 20442 3 2487.185524 830.0677 D-3-phosphoglycerate dehydrogenase OS=Homo sapiens OX=9606 GN=PHGDH PE=1 SV=4 4.32 3212.4 - 3.00E+06 - - - 1.724 - 4.6 0.631 - 885 1 2 1 0.0043 23 0 0 0 2.16E+08 1.04E+08 - - - 9.1539 1 221125_WJC_METTL3_EV_vs_WT_F06.20443.20443.3 2.92E-07 18/76 K.SYNPFDDDGEDEGARPAPWR.D sp|O95721|SNP29_HUMAN 1 2292.9672 2.01 88075 20443 3 2292.971033 765.3297 Synaptosomal-associated protein 29 OS=Homo sapiens OX=9606 GN=SNAP29 PE=1 SV=1 3.96 3212.5 - 1.82E+06 - - - 1.6703 - 2.802 0.644 - 338.2 1 2 0 0.0038 20 0 0 0 3.07E+07 1.53E+07 - - - 8.2185 1 221125_WJC_METTL3_EV_vs_WT_F06.20447.20447.4 1.60E-07 13/96 R.HLLQAPVDDAQEILHSR[166.11].F "sp|Q15436|SC23A_HUMAN,tr|F5H365|F5H365_HUMAN" 2 1951.0151 1.99 88079 20447 4 1951.016968 488.761 Protein transport protein Sec23A OS=Homo sapiens OX=9606 GN=SEC23A PE=1 SV=2 5.21 3213 - 341100 - - - 0.9605 - 2.755 0.497 - 182.9 1 2 0 0.0019 17 0 0 0 6.86E+06 3.44E+06 - - - 3.9032 0.9969 221125_WJC_METTL3_EV_vs_WT_F06.20450.20450.3 7.13E-07 14/100 K.NGFSSVQATQLQTTQSVEGATGSAVK.S "sp|Q14157|UBP2L_HUMAN,tr|F8W726|F8W726_HUMAN" 2 2595.2776 7.88 88080 20450 3 2596.27369 866.0998 Ubiquitin-associated protein 2-like OS=Homo sapiens OX=9606 GN=UBAP2L PE=1 SV=2 6 3213.4 - 2.08E+06 - - - 383.7936 - 3.083 0.496 - 134.8 1 2 0 0.9961 26 0 0 0 1.54E+07 1.95E+06 - - - 6.3843 1 221125_WJC_METTL3_EV_vs_WT_F06.20451.20451.3 1.83E-11 20/76 R.C[160.03]EHDGVMTGANGEVSFINIK.T sp|O15371|EIF3D_HUMAN 1 2176.9881 1.01 88081 20451 3 2176.985829 726.67 Eukaryotic translation initiation factor 3 subunit D OS=Homo sapiens OX=9606 GN=EIF3D PE=1 SV=1 4.65 3213.4 - 980463 - - - -1.0611 - 4.043 0.71 - 532.7 1 2 0 -0.0023 20 0 0 0 1.36E+07 1.34E+07 - - - 9.8443 1 221125_WJC_METTL3_EV_vs_WT_F06.20452.20452.2 2.28E-07 22-Dec K.SFFDNISC[160.03]DDNR[166.11].E "sp|Q8ND56|LS14A_HUMAN,tr|A0A096LP11|A0A096LP11_HUMAN,tr|A0A140TA76|A0A140TA76_HUMAN,tr|A0A0G2JQ95|A0A0G2JQ95_HUMAN" 4 1498.6022 0.93 88082 20452 2 1498.604894 750.3084 Protein LSM14 homolog A OS=Homo sapiens OX=9606 GN=LSM14A PE=1 SV=3 3.93 3213.5 - 1.20E+06 - - - 1.7797 - 2.371 0.681 - 475.2 1 2 0 0.0027 12 0 0 0 2.47E+07 2.67E+07 - - - 6.3415 0.778 221125_WJC_METTL3_EV_vs_WT_F06.20453.20453.3 7.87E-05 16/68 R.NLNHSLPSDFTFQNMNSK.R sp|Q15208|STK38_HUMAN 1 2092.9636 1.32 88083 20453 3 2093.952812 698.6618 Serine\threonine-protein kinase 38 OS=Homo sapiens OX=9606 GN=STK38 PE=1 SV=1 6.74 3213.7 - 926831 - - - 472.6188 - 2.6 0.36 - 279.5 1 2 0 0.9892 18 0 0 0 2.16E+06 1.64E+06 - - - 4.659 1 221125_WJC_METTL3_EV_vs_WT_F06.20454.20454.3 5.65E-14 27/96 K.AALDC[160.03]STSHLDEFYSDPHAVAGALK.S sp|Q68EM7|RHG17_HUMAN 1 2674.2333 1.64 88084 20454 3 2674.233835 892.4184 Rho GTPase-activating protein 17 OS=Homo sapiens OX=9606 GN=ARHGAP17 PE=1 SV=1 4.64 3213.8 - 820726 - - - 0.1885 - 4.216 0.727 - 601.9 1 2 0 0.0005 25 0 0 0 9.20E+06 5.60E+06 - - - 9.9555 0.9999 221125_WJC_METTL3_EV_vs_WT_F06.20458.20458.3 1.45E-07 15/64 K.EAFSLFDKDGDGTITTK.E "sp|P0DP25|CALM3_HUMAN,sp|P0DP23|CALM1_HUMAN,sp|P0DP24|CALM2_HUMAN,tr|F8WBR5|F8WBR5_HUMAN,tr|G3V479|G3V479_HUMAN,tr|M0QZ52|M0QZ52_HUMAN,tr|E7EMB3|E7EMB3_HUMAN" 7 1843.884 1.08 88087 20458 3 1843.888396 615.6353 Calmodulin-3 OS=Homo sapiens OX=9606 GN=CALM3 PE=1 SV=1 4.23 3214.3 - 1.26E+06 - - - 2.3982 - 3.25 0.588 - 326.2 1 2 1 0.0044 17 0 0 0 1.50E+07 1.39E+07 - - - 8.072 0.9999 221125_WJC_METTL3_EV_vs_WT_F06.20460.20460.3 2.84E-08 20/88 R.ALQSGQC[160.03]AGAALDVFTEEPPR[166.11]DR[166.11].A "sp|O43175|SERA_HUMAN,tr|A0A286YF78|A0A286YF78_HUMAN,tr|A0A2C9F2M7|A0A2C9F2M7_HUMAN,tr|A0A286YF22|A0A286YF22_HUMAN,tr|A0A286YFL2|A0A286YFL2_HUMAN,tr|A0A286YFA2|A0A286YFA2_HUMAN" 6 2507.1978 2.07 88089 20460 3 2507.199846 836.7399 D-3-phosphoglycerate dehydrogenase OS=Homo sapiens OX=9606 GN=PHGDH PE=1 SV=4 4.32 3214.5 - 3.99E+06 - - - 0.8256 - 3.649 0.576 - 400.1 1 2 1 0.0021 23 0 0 0 2.09E+08 1.01E+08 - - - 7.998 0.9999 221125_WJC_METTL3_EV_vs_WT_F06.20463.20463.3 7.02E-08 16/44 R.NMQDLVEDLKNK.Y "sp|P48668|K2C6C_HUMAN,sp|P04259|K2C6B_HUMAN" 2 1445.7184 12.12 88092 20463 3 1445.719681 482.9134 "Keratin, type II cytoskeletal 6C OS=Homo sapiens OX=9606 GN=KRT6C PE=1 SV=3" 4.56 3214.8 - 844112 - - - 0.866 - 3.115 0.563 - 428.2 1 2 1 0.0013 12 0 0 0 2.26E+07 1.86E+06 - - - 7.966 1 221125_WJC_METTL3_EV_vs_WT_F06.20467.20467.3 1.18E-10 18/68 K.YVHYEIDAC[160.03]MDSEAPGSK[136.11].D "sp|Q86U44|MTA70_HUMAN,tr|H0YFV6|H0YFV6_HUMAN" 2 2078.8805 0.01 88094 20467 3 2078.881524 693.9674 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 4.31 3215.2 - 1.85E+06 - - - 0.4964 - 3.47 0.71 - 339.1 1 2 0 0.001 18 0 0 0 2.74E+05 5.05E+07 - - - 9.5536 1 221125_WJC_METTL3_EV_vs_WT_F06.20468.20468.3 7.60E-15 23/76 K.GLSEDTTEETLKESFDGSVR.A "sp|P19338|NUCL_HUMAN,tr|A0A7I2V699|A0A7I2V699_HUMAN,tr|A0A7I2V2U7|A0A7I2V2U7_HUMAN,tr|A0A7I2V3F3|A0A7I2V3F3_HUMAN,tr|A0A7I2V428|A0A7I2V428_HUMAN,tr|H7BY16|H7BY16_HUMAN,tr|A0A7I2V5M5|A0A7I2V5M5_HUMAN,tr|C9JLB1|C9JLB1_HUMAN" 8 2199.0179 1 88095 20468 3 2199.023669 734.0132 Nucleolin OS=Homo sapiens OX=9606 GN=NCL PE=1 SV=3 4.08 3215.3 - 1.82E+06 - - - 2.6225 - 4.418 0.59 - 815.4 1 2 1 0.0058 20 0 0 0 1.24E+08 1.25E+08 - - - 8.7206 0.9195 221125_WJC_METTL3_EV_vs_WT_F06.20469.20469.3 0.000359 20/100 K.NGFSSVQATQLQTTQSVEGATGSAVK[136.11].S "sp|Q14157|UBP2L_HUMAN,tr|F8W726|F8W726_HUMAN" 2 2603.2918 -1 88096 20469 3 2604.275585 868.7712 Ubiquitin-associated protein 2-like OS=Homo sapiens OX=9606 GN=UBAP2L PE=1 SV=2 6 3215.4 - 2.94E+06 - - - 377.8854 - 3.192 0.483 - 312.7 1 2 0 0.9837 26 0 0 0 0.00E+00 0.00E+00 - - - 6.3227 0.999 221125_WJC_METTL3_EV_vs_WT_F06.20470.20470.3 4.58E-07 20/52 T.SSHNLQSIFNIGSR.G "sp|P43243|MATR3_HUMAN,tr|A8MXP9|A8MXP9_HUMAN,tr|D6R991|D6R991_HUMAN,tr|D6REK4|D6REK4_HUMAN,tr|A0A0R4J2E8|A0A0R4J2E8_HUMAN,tr|D6RCM3|D6RCM3_HUMAN,tr|D6R8Z5|D6R8Z5_HUMAN,tr|D6REM6|D6REM6_HUMAN" 8 1558.7852 1.33 88097 20470 3 1558.785134 520.6023 Matrin-3 OS=Homo sapiens OX=9606 GN=MATR3 PE=1 SV=2 9.49 3215.5 - 1.67E+06 - - - -0.0449 - 3.373 0.597 - 687.6 1 1 0 -0.0001 14 0 0 0 2.47E+08 1.87E+08 - - - 8.427 1 221125_WJC_METTL3_EV_vs_WT_F06.20472.20472.3 3.06E-09 19/104 R.IGQELLFPPQENVQDAGAPGGHTQNLR.C sp|Q5JSZ5|PRC2B_HUMAN 1 2885.442 1.77 88099 20472 3 2885.44362 962.8213 Protein PRRC2B OS=Homo sapiens OX=9606 GN=PRRC2B PE=1 SV=2 4.65 3215.7 - 945814 - - - 0.5549 - 3.574 0.555 - 144.8 1 2 0 0.0016 27 0 0 0 2.12E+07 1.20E+07 - - - 7.6575 0.9976 221125_WJC_METTL3_EV_vs_WT_F06.20476.20476.3 5.47E-06 15/52 T.SSHNLQSIFNIGSR[166.11].G "sp|P43243|MATR3_HUMAN,tr|A8MXP9|A8MXP9_HUMAN,tr|D6R991|D6R991_HUMAN,tr|D6REK4|D6REK4_HUMAN,tr|A0A0R4J2E8|A0A0R4J2E8_HUMAN,tr|D6RCM3|D6RCM3_HUMAN,tr|D6R8Z5|D6R8Z5_HUMAN,tr|D6REM6|D6REM6_HUMAN" 8 1568.7935 1.33 88101 20476 3 1568.79413 523.9384 Matrin-3 OS=Homo sapiens OX=9606 GN=MATR3 PE=1 SV=2 9.49 3216.3 - 3.45E+06 - - - 0.4182 - 2.733 0.506 - 300.5 1 1 0 0.0007 14 0 0 0 2.47E+08 1.87E+08 - - - 6.8531 0.9994 221125_WJC_METTL3_EV_vs_WT_F06.20477.20477.4 2.82E-05 16/114 K.RPVFPPLC[160.03]GDGLLSGKEETR.K "sp|Q9NRX1|PNO1_HUMAN,tr|F8WBJ6|F8WBJ6_HUMAN" 2 2227.1419 0.29 88102 20477 4 2227.137428 557.7928 RNA-binding protein PNO1 OS=Homo sapiens OX=9606 GN=PNO1 PE=1 SV=1 6.17 3216.4 - 646425 - - - -2.0246 - 2.904 0.413 - 120.6 1 2 1 -0.0045 20 0 0 0 9.37E+06 3.19E+07 - - - 3.1759 1 221125_WJC_METTL3_EV_vs_WT_F06.20485.20485.3 7.96E-13 28/92 R.GR[166.11]GDWSVGAPGGVQEITYTVPADK[136.11].C sp|Q96I24|FUBP3_HUMAN 1 2477.2306 6.22 88107 20485 3 2477.23652 826.7508 Far upstream element-binding protein 3 OS=Homo sapiens OX=9606 GN=FUBP3 PE=1 SV=2 4.56 3217.5 - 3.72E+06 - - - 2.4011 - 4.754 0.665 - 514.1 1 2 1 0.0059 24 0 0 0 4.03E+08 6.47E+07 - - - 9.5733 0.9999 221125_WJC_METTL3_EV_vs_WT_F06.20486.20486.4 1.46E-10 21/132 R.ALQSGQC[160.03]AGAALDVFTEEPPRDR.A "sp|O43175|SERA_HUMAN,tr|A0A286YF78|A0A286YF78_HUMAN,tr|A0A2C9F2M7|A0A2C9F2M7_HUMAN,tr|A0A286YF22|A0A286YF22_HUMAN,tr|A0A286YFL2|A0A286YFL2_HUMAN,tr|A0A286YFA2|A0A286YFA2_HUMAN" 6 2487.1812 1.77 88108 20486 4 2487.183876 622.8026 D-3-phosphoglycerate dehydrogenase OS=Homo sapiens OX=9606 GN=PHGDH PE=1 SV=4 4.32 3217.6 - 1.23E+06 - - - 1.0614 - 3.746 0.594 - 301.7 1 2 1 0.0026 23 0 0 0 2.05E+07 1.16E+07 - - - 4.8233 0.976 221125_WJC_METTL3_EV_vs_WT_F06.20488.20488.4 0.0896 15/72 R.EKVEVQLPELFHK.L "sp|Q13303|KCAB2_HUMAN,tr|A0A590UJJ4|A0A590UJJ4_HUMAN,tr|A0A5F9UN28|A0A5F9UN28_HUMAN,tr|A0A590UJB6|A0A590UJB6_HUMAN" 4 1594.8719 1.85 88110 20488 4 1594.87204 399.7252 Voltage-gated potassium channel subunit beta-2 OS=Homo sapiens OX=9606 GN=KCNAB2 PE=1 SV=2 5.5 3217.8 - 935988 - - - 0.0922 - 2.236 0.209 - 259.4 1 2 1 0.0001 13 0 0 0 1.91E+08 1.03E+08 - - - 1.3434 1 221125_WJC_METTL3_EV_vs_WT_F06.20489.20489.2 1.68E-09 15/50 K.NGFSSVQATQLQTTQSVEGATGSAVK.S "sp|Q14157|UBP2L_HUMAN,tr|F8W726|F8W726_HUMAN" 2 2595.2776 -1 88111 20489 2 2596.262346 1298.6461 Ubiquitin-associated protein 2-like OS=Homo sapiens OX=9606 GN=UBAP2L PE=1 SV=2 6 3217.9 - 446252 - - - 379.4226 - 3.545 0.711 - 580.7 1 2 0 0.9847 26 0 0 0 0.00E+00 0.00E+00 - - - 7.0946 1 221125_WJC_METTL3_EV_vs_WT_F06.20492.20492.3 8.28E-12 16/72 R.AGDWQC[160.03]PNPGC[160.03]GNQNFAWR.T "sp|Q01844|EWS_HUMAN,tr|B0QYK0|B0QYK0_HUMAN,tr|A0A0D9SFL3|A0A0D9SFL3_HUMAN,tr|C9JGE3|C9JGE3_HUMAN" 4 2233.917 0.82 88112 20492 3 2233.917309 745.6463 RNA-binding protein EWS OS=Homo sapiens OX=9606 GN=EWSR1 PE=1 SV=1 5.86 3218.3 - 1.83E+06 - - - 0.1204 - 3.574 0.619 - 353 1 2 0 0.0003 19 0 0 0 1.05E+08 1.29E+08 - - - 8.5704 1 221125_WJC_METTL3_EV_vs_WT_F06.20495.20495.4 1.28E-10 20/156 K.IGEEQSPEDAEDGPPELLFIHGGHTAK.L "sp|Q09028|RBBP4_HUMAN,tr|H0YCT5|H0YCT5_HUMAN,tr|H0YDK2|H0YDK2_HUMAN,tr|H0YEU5|H0YEU5_HUMAN,tr|H0YF10|H0YF10_HUMAN" 5 2872.3515 2.55 88115 20495 4 2872.34584 719.0952 Histone-binding protein RBBP4 OS=Homo sapiens OX=9606 GN=RBBP4 PE=1 SV=3 4.24 3218.7 - 743762 - - - -1.9817 - 3.82 0.639 - 254.4 1 2 0 -0.0057 27 0 0 0 1.78E+08 6.99E+07 - - - 5.2056 1 221125_WJC_METTL3_EV_vs_WT_F06.20502.20502.2 4.23E-05 16/36 R.AGDWQC[160.03]PNPGC[160.03]GNQNFAWR[166.11].T "sp|Q01844|EWS_HUMAN,tr|B0QYK0|B0QYK0_HUMAN,tr|A0A0D9SFL3|A0A0D9SFL3_HUMAN,tr|C9JGE3|C9JGE3_HUMAN" 4 2243.9253 1.31 88120 20502 2 2243.922757 1122.9699 RNA-binding protein EWS OS=Homo sapiens OX=9606 GN=EWSR1 PE=1 SV=1 5.86 3219.5 - 611591 - - - -1.1377 - 3.616 0.688 - 590.1 1 2 0 -0.0026 19 0 0 0 1.55E+07 1.18E+07 - - - 7.2819 1 221125_WJC_METTL3_EV_vs_WT_F06.20510.20510.3 0.000182 20/72 R.AGDWQC[160.03]PNPGC[160.03]GNQNFAWR[166.11].T "sp|Q01844|EWS_HUMAN,tr|B0QYK0|B0QYK0_HUMAN,tr|A0A0D9SFL3|A0A0D9SFL3_HUMAN,tr|C9JGE3|C9JGE3_HUMAN" 4 2243.9253 0.82 88126 20510 3 2243.924725 748.9824 RNA-binding protein EWS OS=Homo sapiens OX=9606 GN=EWSR1 PE=1 SV=1 5.86 3220.4 - 5.74E+06 - - - -0.2607 - 3.894 0.658 - 581.8 1 2 0 -0.0006 19 0 0 0 1.05E+08 1.29E+08 - - - 9.2158 0.9908 221125_WJC_METTL3_EV_vs_WT_F06.20512.20512.2 0.039 14/26 T.SSHNLQSIFNIGSR.G "sp|P43243|MATR3_HUMAN,tr|A8MXP9|A8MXP9_HUMAN,tr|D6R991|D6R991_HUMAN,tr|D6REK4|D6REK4_HUMAN,tr|A0A0R4J2E8|A0A0R4J2E8_HUMAN,tr|D6RCM3|D6RCM3_HUMAN,tr|D6R8Z5|D6R8Z5_HUMAN,tr|D6REM6|D6REM6_HUMAN" 8 1558.7852 1.62 88128 20512 2 1558.782393 780.3999 Matrin-3 OS=Homo sapiens OX=9606 GN=MATR3 PE=1 SV=2 9.49 3220.6 - 1.09E+06 - - - -1.8033 - 3.139 0.515 - 681.6 1 1 0 -0.0028 14 0 0 0 2.79E+07 1.72E+07 - - - 5.7145 1 221125_WJC_METTL3_EV_vs_WT_F06.20517.20517.2 3.16E-05 27/44 K.EIETYHNLLEGGQEDFESSGAGK.L "sp|P35527|K1C9_HUMAN,tr|K7EQQ3|K7EQQ3_HUMAN" 2 2509.1245 999 88131 20517 2 2509.125783 1255.5695 "Keratin, type I cytoskeletal 9 OS=Homo sapiens OX=9606 GN=KRT9 PE=1 SV=3" 4.14 3221.2 - 1.96E+06 - - - 0.5145 - 5.682 0.744 - 2080.5 1 2 0 0.0013 23 0 0 0 1.20E+09 0.00E+00 - - - 8.807 1 221125_WJC_METTL3_EV_vs_WT_F06.20518.20518.2 6.03E-12 16/26 T.SSHNLQSIFNIGSR[166.11].G "sp|P43243|MATR3_HUMAN,tr|A8MXP9|A8MXP9_HUMAN,tr|D6R991|D6R991_HUMAN,tr|D6REK4|D6REK4_HUMAN,tr|A0A0R4J2E8|A0A0R4J2E8_HUMAN,tr|D6RCM3|D6RCM3_HUMAN,tr|D6R8Z5|D6R8Z5_HUMAN,tr|D6REM6|D6REM6_HUMAN" 8 1568.7935 2.39 88132 20518 2 1568.788661 785.404 Matrin-3 OS=Homo sapiens OX=9606 GN=MATR3 PE=1 SV=2 9.49 3221.4 - 631221 - - - -3.068 - 3.323 0.551 - 1038.6 1 1 0 -0.0048 14 0 0 0 4.24E+07 1.77E+07 - - - 6.1227 1 221125_WJC_METTL3_EV_vs_WT_F06.20519.20519.3 2.22E-12 21/92 R.ELLESNFTLVGDDGTNK[136.11]EATSTGK[136.11].L sp|Q96A33|CCD47_HUMAN 1 2541.2417 1.07 88133 20519 3 2541.230613 848.0878 PAT complex subunit CCDC47 OS=Homo sapiens OX=9606 GN=CCDC47 PE=1 SV=1 4.18 3221.5 - 899668 - - - -4.3656 - 4.403 0.638 - 333.9 1 2 1 -0.0111 24 0 0 0 3.53E+07 3.29E+07 - - - 9.0928 1 221125_WJC_METTL3_EV_vs_WT_F06.20520.20520.3 1.58E-05 13/64 R.GAPPSSNIEDFHGLLPK.G "sp|P43243|MATR3_HUMAN,tr|A8MXP9|A8MXP9_HUMAN,tr|D6R991|D6R991_HUMAN,tr|A0A0R4J2E8|A0A0R4J2E8_HUMAN,tr|H0Y8T4|H0Y8T4_HUMAN,tr|D6REM6|D6REM6_HUMAN" 6 1777.8999 1.37 88134 20520 3 1777.900461 593.6406 Matrin-3 OS=Homo sapiens OX=9606 GN=MATR3 PE=1 SV=2 5.32 3221.6 - 604837 - - - 0.3161 - 2.45 0.472 - 177.1 1 2 0 0.0006 17 0 0 0 3.91E+08 2.86E+08 - - - 6.066 0.9999 221125_WJC_METTL3_EV_vs_WT_F06.20522.20522.4 0.156 19/108 K.ILGSGISSSSVLHGMVFK[136.11]K[136.11].E sp|P50990|TCPQ_HUMAN 1 1962.0943 0.4 88136 20522 4 1962.092172 491.5309 T-complex protein 1 subunit theta OS=Homo sapiens OX=9606 GN=CCT8 PE=1 SV=4 10 3221.9 - 399763 - - - -1.0942 - 3.862 0.419 - 269.7 1 2 0 -0.0021 19 0 0 0 2.13E+06 5.38E+06 - - - 3.3295 0.9999 221125_WJC_METTL3_EV_vs_WT_F06.20526.20526.3 0.0199 13/64 K.FVINYDYPNSSEDYIHR.L "sp|P17844|DDX5_HUMAN,tr|J3KTA4|J3KTA4_HUMAN,tr|A0A0G2JLI4|A0A0G2JLI4_HUMAN" 3 2130.9647 2.67 88138 20526 3 2130.959861 711.3288 Probable ATP-dependent RNA helicase DDX5 OS=Homo sapiens OX=9606 GN=DDX5 PE=1 SV=1 4.54 3222.4 - 647201 - - - -2.2633 - 2.568 0.457 - 171.5 1 2 0 -0.0048 17 0 0 0 3.50E+07 1.31E+07 - - - 6.0164 1 221125_WJC_METTL3_EV_vs_WT_F06.20529.20529.3 5.23E-08 17/116 R.GEPFASHSLVSATSVGDSGTAESPSLLQDK.G sp|Q96IZ5|RBM41_HUMAN 1 2973.4203 3.33 88141 20529 3 2973.427212 992.1474 RNA-binding protein 41 OS=Homo sapiens OX=9606 GN=RBM41 PE=1 SV=2 4.31 3222.7 - 548645 - - - 2.3111 - 3.726 0.656 - 258.7 1 2 0 0.0069 30 0 0 0 3.71E+06 1.11E+06 - - - 8.878 1 221125_WJC_METTL3_EV_vs_WT_F06.20533.20533.3 2.50E-09 24/92 R.ELLESNFTLVGDDGTNKEATSTGK.L sp|Q96A33|CCD47_HUMAN 1 2525.2133 1.07 88143 20533 3 2525.214469 842.745 PAT complex subunit CCDC47 OS=Homo sapiens OX=9606 GN=CCDC47 PE=1 SV=1 4.18 3223.1 - 2.29E+06 - - - 0.4602 - 4.847 0.613 - 532 1 2 1 0.0012 24 0 0 0 3.53E+07 3.29E+07 - - - 9.0399 1 221125_WJC_METTL3_EV_vs_WT_F06.20534.20534.4 1.59E-11 30/156 K.IGEEQSPEDAEDGPPELLFIHGGHTAK[136.11].L "sp|Q09028|RBBP4_HUMAN,tr|H0YCT5|H0YCT5_HUMAN,tr|H0YDK2|H0YDK2_HUMAN,tr|H0YEU5|H0YEU5_HUMAN,tr|H0YF10|H0YF10_HUMAN" 5 2880.3657 2.56 88144 20534 4 2880.361085 721.0987 Histone-binding protein RBBP4 OS=Homo sapiens OX=9606 GN=RBBP4 PE=1 SV=3 4.24 3223.3 - 1.25E+06 - - - -1.6133 - 4.902 0.705 - 765.2 1 2 0 -0.0046 27 0 0 0 1.78E+08 6.96E+07 - - - 5.8584 0.9951 221125_WJC_METTL3_EV_vs_WT_F06.20537.20537.3 0.00041 15/56 S.TSSHNLQSIFNIGSR[166.11].G "sp|P43243|MATR3_HUMAN,tr|A8MXP9|A8MXP9_HUMAN,tr|D6R991|D6R991_HUMAN,tr|D6REK4|D6REK4_HUMAN,tr|A0A0R4J2E8|A0A0R4J2E8_HUMAN,tr|D6RCM3|D6RCM3_HUMAN,tr|D6R8Z5|D6R8Z5_HUMAN,tr|D6REM6|D6REM6_HUMAN" 8 1669.8412 1.24 88147 20537 3 1669.842004 557.621 Matrin-3 OS=Homo sapiens OX=9606 GN=MATR3 PE=1 SV=2 9.44 3223.6 - 692956 - - - 0.5102 - 2.695 0.435 - 262.2 1 1 0 0.0009 15 0 0 0 1.52E+08 1.23E+08 - - - 5.9765 0.96 221125_WJC_METTL3_EV_vs_WT_F06.20541.20541.3 1.42E-07 16/56 S.TSSHNLQSIFNIGSR.G "sp|P43243|MATR3_HUMAN,tr|A8MXP9|A8MXP9_HUMAN,tr|D6R991|D6R991_HUMAN,tr|D6REK4|D6REK4_HUMAN,tr|A0A0R4J2E8|A0A0R4J2E8_HUMAN,tr|D6RCM3|D6RCM3_HUMAN,tr|D6R8Z5|D6R8Z5_HUMAN,tr|D6REM6|D6REM6_HUMAN" 8 1659.8329 1.24 88149 20541 3 1659.826548 554.2849 Matrin-3 OS=Homo sapiens OX=9606 GN=MATR3 PE=1 SV=2 9.44 3224.1 - 1.29E+06 - - - -3.816 - 2.592 0.423 - 347.9 1 1 0 -0.0063 15 0 0 0 1.52E+08 1.23E+08 - - - 5.7395 1 221125_WJC_METTL3_EV_vs_WT_F06.20550.20550.4 1.12E-07 24/156 R.VIQPHGGGSNPLEGTQHLQDVPYVMVR.E sp|Q14126|DSG2_HUMAN 1 2927.4712 1.58 88157 20550 4 2927.465262 732.8751 Desmoglein-2 OS=Homo sapiens OX=9606 GN=DSG2 PE=1 SV=2 5.99 3224.8 - 1.83E+06 - - - -2.0318 - 4.425 0.593 - 341.7 1 2 0 -0.0059 27 0 0 0 3.40E+07 2.15E+07 - - - 4.8512 0.9998 221125_WJC_METTL3_EV_vs_WT_F06.20556.20556.3 1.01E-06 17/52 K.NKLNDLEDALQQAK.E sp|P04264|K2C1_HUMAN 1 1598.8264 401727.72 88161 20556 3 1598.822645 533.9494 "Keratin, type II cytoskeletal 1 OS=Homo sapiens OX=9606 GN=KRT1 PE=1 SV=6" 4.56 3225.6 - 1.90E+06 - - - -2.3486 - 3.494 0.481 - 546 1 2 1 -0.0038 14 0 0 0 4.35E+10 1.08E+05 - - - 7.2263 0.9998 221125_WJC_METTL3_EV_vs_WT_F06.20561.20561.3 1.21E-05 14/56 K.HKDAAIYLVTSLASK.A sp|P55060|XPO2_HUMAN 1 1615.8934 0.76 88164 20561 3 1615.891712 539.6384 Exportin-2 OS=Homo sapiens OX=9606 GN=CSE1L PE=1 SV=3 8.51 3226.2 - 1.12E+06 - - - -1.018 - 2.567 0.455 - 241.1 1 2 1 -0.0016 15 0 0 0 9.95E+07 1.31E+08 - - - 6.0723 1 221125_WJC_METTL3_EV_vs_WT_F06.20563.20563.2 8.69E-06 21/26 K.NKLNDLEDALQQAK.E sp|P04264|K2C1_HUMAN 1 1598.8264 999 88166 20563 2 1598.824478 800.4205 "Keratin, type II cytoskeletal 1 OS=Homo sapiens OX=9606 GN=KRT1 PE=1 SV=6" 4.56 3226.4 - 1.20E+06 - - - -1.2021 - 3.903 0.666 - 1826.5 1 2 1 -0.0019 14 0 0 0 1.80E+10 0.00E+00 - - - 7.3767 0.9995 221125_WJC_METTL3_EV_vs_WT_F06.20569.20569.3 1.95E-07 18/56 K.HK[136.11]DAAIYLVTSLASK[136.11].A sp|P55060|XPO2_HUMAN 1 1631.9218 0.76 88170 20569 3 1631.915429 544.9812 Exportin-2 OS=Homo sapiens OX=9606 GN=CSE1L PE=1 SV=3 8.51 3227.1 - 1.52E+06 - - - -3.8776 - 3.218 0.528 - 372.9 1 2 1 -0.0063 15 0 0 0 9.95E+07 1.31E+08 - - - 7.4746 0.9995 221125_WJC_METTL3_EV_vs_WT_F06.20572.20572.3 4.96E-08 18/64 R.GAPPSSNIEDFHGLLPK[136.11].G "sp|P43243|MATR3_HUMAN,tr|A8MXP9|A8MXP9_HUMAN,tr|D6R991|D6R991_HUMAN,tr|A0A0R4J2E8|A0A0R4J2E8_HUMAN,tr|H0Y8T4|H0Y8T4_HUMAN,tr|D6REM6|D6REM6_HUMAN" 6 1785.9141 1.38 88171 20572 3 1785.902876 596.312 Matrin-3 OS=Homo sapiens OX=9606 GN=MATR3 PE=1 SV=2 5.32 3227.5 - 1.09E+06 - - - -6.2842 - 3.135 0.563 - 370.6 1 2 0 -0.0112 17 0 0 0 4.92E+08 3.57E+08 - - - 7.7004 1 221125_WJC_METTL3_EV_vs_WT_F06.20576.20576.3 8.30E-06 21/60 K.KIFDIDEAEEGVKDLK.L sp|P20042|IF2B_HUMAN 1 1847.9517 1.11 88173 20576 3 1847.94763 616.9912 Eukaryotic translation initiation factor 2 subunit 2 OS=Homo sapiens OX=9606 GN=EIF2S2 PE=1 SV=2 4.3 3228 - 1.82E+06 - - - -2.1808 - 4.355 0.578 - 464.4 1 2 1 -0.004 16 0 0 0 4.18E+07 3.76E+07 - - - 8.7582 0.9999 221125_WJC_METTL3_EV_vs_WT_F06.20582.20582.4 5.35E-07 15/132 K.EIETYHNLLEGGQEDFESSGAGK.L "sp|P35527|K1C9_HUMAN,tr|K7EQQ3|K7EQQ3_HUMAN" 2 2509.1245 60.98 88175 20582 4 2509.117026 628.2884 "Keratin, type I cytoskeletal 9 OS=Homo sapiens OX=9606 GN=KRT9 PE=1 SV=3" 4.14 3228.8 - 1.16E+07 - - - -2.9755 - 3.126 0.573 - 131.2 1 2 0 -0.0075 23 0 0 0 2.79E+08 4.57E+06 - - - 4.5806 0.9998 221125_WJC_METTL3_EV_vs_WT_F06.20586.20586.3 1.56E-10 20/60 K.K[136.11]IFDIDEAEEGVK[136.11]DLK[136.11].L sp|P20042|IF2B_HUMAN 1 1871.9943 1.11 88177 20586 3 1871.989138 625.0054 Eukaryotic translation initiation factor 2 subunit 2 OS=Homo sapiens OX=9606 GN=EIF2S2 PE=1 SV=2 4.3 3229.2 - 1.58E+06 - - - -2.7361 - 3.881 0.526 - 388.3 1 2 1 -0.0051 16 0 0 0 4.18E+07 3.76E+07 - - - 7.8825 1 221125_WJC_METTL3_EV_vs_WT_F06.20588.20588.3 4.57E-16 26/96 R.MSGDLSSNVTVSVTSSTISSNVASK.A sp|P35908|K22E_HUMAN 1 2457.1905 417.43 88178 20588 3 2457.188981 820.0708 "Keratin, type II cytoskeletal 2 epidermal OS=Homo sapiens OX=9606 GN=KRT2 PE=1 SV=2" 5.59 3229.4 - 4.21E+06 - - - -0.6031 - 4.832 0.688 - 700.8 1 2 0 -0.0015 25 0 0 0 2.75E+08 6.59E+05 - - - 9.8342 0.9932 221125_WJC_METTL3_EV_vs_WT_F06.20596.20596.4 4.97E-05 20/108 R.GLLQDDAHPTLVTYADHSK[136.11].L "sp|Q86U44|MTA70_HUMAN,tr|F5H6D8|F5H6D8_HUMAN,tr|H0YFV6|H0YFV6_HUMAN,tr|B4DTN4|B4DTN4_HUMAN" 4 2088.0367 0.06 88182 20596 4 2089.032428 523.0165 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 5.13 3230.4 - 1.65E+06 - - - 476.857 - 3.024 0.509 - 225.8 1 2 0 0.9957 19 0 0 0 3.55E+06 5.93E+07 - - - 3.7549 1 221125_WJC_METTL3_EV_vs_WT_F06.20599.20599.3 2.61E-10 18/88 K.EIETYHNLLEGGQEDFESSGAGK.L "sp|P35527|K1C9_HUMAN,tr|K7EQQ3|K7EQQ3_HUMAN" 2 2509.1245 1172.1 88184 20599 3 2509.121156 837.3821 "Keratin, type I cytoskeletal 9 OS=Homo sapiens OX=9606 GN=KRT9 PE=1 SV=3" 4.14 3230.7 - 6.17E+08 - - - -1.3295 - 3.692 0.718 - 416.7 1 2 0 -0.0033 23 0 0 0 3.64E+10 3.10E+07 - - - 9.6083 0.9997 221125_WJC_METTL3_EV_vs_WT_F06.20610.20610.3 2.75E-06 16/68 R.AQAEAQQPTFDALRDELR.G "sp|Q15149|PLEC_HUMAN,tr|H0YDN1|H0YDN1_HUMAN" 2 2058.013 2.25 88190 20610 3 2058.008338 687.0116 Plectin OS=Homo sapiens OX=9606 GN=PLEC PE=1 SV=3 4.32 3232.1 - 3.35E+06 - - - -2.2804 - 2.842 0.48 - 266.4 1 2 1 -0.0047 18 0 0 0 8.84E+07 3.93E+07 - - - 6.4912 0.9907 221125_WJC_METTL3_EV_vs_WT_F06.20616.20616.4 8.00E-06 21/174 L.LTTVGWDHQVVHHVVPTEPLPAPGPASVTE.- "sp|Q9BQA1|MEP50_HUMAN,tr|H0Y711|H0Y711_HUMAN" 2 3169.6196 - 88194 20616 4 3169.617099 793.4122 Methylosome protein 50 OS=Homo sapiens OX=9606 GN=WDR77 PE=1 SV=1 5.3 3232.8 - 2.79E+06 - - - -0.8045 - 3.554 0.429 - 150.6 1 1 0 -0.0025 30 0 0 0 - - - - - 3.3473 0.9085 221125_WJC_METTL3_EV_vs_WT_F06.20629.20629.2 0.00832 14-Sep L.EDALQQAK.E sp|P04264|K2C1_HUMAN 1 901.4505 999 88202 20629 2 901.449026 451.7325 "Keratin, type II cytoskeletal 1 OS=Homo sapiens OX=9606 GN=KRT1 PE=1 SV=6" 4.37 3234.5 - 2.72E+06 - - - -1.6473 - 1.969 0.176 - 288.9 1 1 0 -0.0015 8 0 0 0 8.07E+07 0.00E+00 - - - 2.3839 0.9462 221125_WJC_METTL3_EV_vs_WT_F06.20634.20634.2 0.682 26-Dec D.GEAGIEAVGSAAGR[166.11].- tr|J3QS04|J3QS04_HUMAN 1 1253.6239 0.07 88205 20634 2 1253.623143 627.8193 SAP30-binding protein OS=Homo sapiens OX=9606 GN=SAP30BP PE=1 SV=1 4.53 3235.1 - 2.51E+06 - - - -0.6429 - 2.393 0.168 - 404.3 1 1 0 -0.0008 14 0 0 0 4.24E+06 6.46E+07 - - - 2.4712 0.7785 221125_WJC_METTL3_EV_vs_WT_F06.20635.20635.2 0.302 24-Jul K.NKINDNEIHQFNK[136.11].N "sp|P51587|BRCA2_HUMAN,tr|A0A7P0T9D7|A0A7P0T9D7_HUMAN,tr|A0A7P0TAP7|A0A7P0TAP7_HUMAN" 3 1620.81 - 88206 20635 2 1620.804252 811.4123 Breast cancer type 2 susceptibility protein OS=Homo sapiens OX=9606 GN=BRCA2 PE=1 SV=3 6.75 3235.2 - 2.91E+06 - - - -3.5266 - 1.666 0.157 - 83.8 3 2 1 -0.0057 13 0 0 0 - - - - - 1.2957 1 221125_WJC_METTL3_EV_vs_WT_F06.20641.20641.4 9.92E-11 21/144 K.AQIQQFHSQIAAQTSASVLAEELHK[136.11].V sp|Q86UP2|KTN1_HUMAN 1 2742.418 2.06 88209 20641 4 2742.418099 686.6118 Kinectin OS=Homo sapiens OX=9606 GN=KTN1 PE=1 SV=1 6.01 3236 - 5.35E+06 - - - 0.0208 - 3.407 0.601 - 223.7 1 2 0 0.0001 25 0 0 0 2.21E+08 1.08E+08 - - - 4.8471 0.9999 221125_WJC_METTL3_EV_vs_WT_F06.20644.20644.4 4.40E-08 21/144 K.AQIQQFHSQIAAQTSASVLAEELHK.V sp|Q86UP2|KTN1_HUMAN 1 2734.4038 2.06 88211 20644 4 2734.401333 684.6082 Kinectin OS=Homo sapiens OX=9606 GN=KTN1 PE=1 SV=1 6.01 3236.3 - 1.09E+07 - - - -0.9176 - 4.206 0.415 - 252.1 1 2 0 -0.0025 25 0 0 0 2.21E+08 1.08E+08 - - - 3.2944 0.9999 221125_WJC_METTL3_EV_vs_WT_F06.20651.20651.3 3.15E-11 21/92 K.ISTEVGITNVDLSTVDKDQSIAPK.T sp|P04844|RPN2_HUMAN 1 2529.3174 1.81 88215 20651 3 2529.312065 844.1131 Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit 2 OS=Homo sapiens OX=9606 GN=RPN2 PE=1 SV=3 4.23 3237.1 - 2.00E+06 - - - -2.1006 - 4.447 0.563 - 413.5 1 2 1 -0.0053 24 0 0 0 4.56E+07 2.52E+07 - - - 8.2813 1 221125_WJC_METTL3_EV_vs_WT_F06.20659.20659.3 2.07E-06 19/52 R.DK[136.11]EVGNLYDMFHTR[166.11].N "sp|Q9Y3Z3|SAMH1_HUMAN,tr|A0A2R8YD90|A0A2R8YD90_HUMAN,tr|A0A2R8YCS7|A0A2R8YCS7_HUMAN" 3 1741.8213 0.42 88219 20659 3 1741.811973 581.6144 Deoxynucleoside triphosphate triphosphohydrolase SAMHD1 OS=Homo sapiens OX=9606 GN=SAMHD1 PE=1 SV=2 5.38 3238 - 1.42E+06 - - - -5.3404 - 3.452 0.648 - 450 1 2 1 -0.0093 14 0 0 0 8.76E+06 2.07E+07 - - - 9.0545 0.9999 221125_WJC_METTL3_EV_vs_WT_F06.20671.20671.4 4.90E-09 29/108 K.NTK[136.11]EPPLSLTIHLTSPVVR[166.11].E "sp|Q12906|ILF3_HUMAN,tr|K7EQR9|K7EQR9_HUMAN,tr|K7EKY0|K7EKY0_HUMAN,tr|K7EPG3|K7EPG3_HUMAN,tr|K7EKJ9|K7EKJ9_HUMAN" 5 2119.212 1.07 88225 20671 4 2119.212441 530.8103 Interleukin enhancer-binding factor 3 OS=Homo sapiens OX=9606 GN=ILF3 PE=1 SV=3 8.75 3239.6 - 3.60E+06 - - - 0.2038 - 4.775 0.589 - 716 1 2 1 0.0004 19 0 0 0 1.12E+08 1.05E+08 - - - 4.8814 1 221125_WJC_METTL3_EV_vs_WT_F06.20672.20672.3 7.50E-08 20/60 K.AKVDLKPLLSSLSANK.E "sp|Q9NRA8|4ET_HUMAN,tr|B1AKL4|B1AKL4_HUMAN,tr|B0QYZ7|B0QYZ7_HUMAN" 3 1682.9931 1.71 88226 20672 3 1682.988945 562.005 Eukaryotic translation initiation factor 4E transporter OS=Homo sapiens OX=9606 GN=EIF4ENIF1 PE=1 SV=2 9.7 3239.7 - 3.38E+06 - - - -2.4516 - 3.612 0.637 - 273.4 1 2 1 -0.0041 16 0 0 0 8.24E+07 4.82E+07 - - - 8.936 0.9995 221125_WJC_METTL3_EV_vs_WT_F06.20673.20673.4 7.05E-05 14/90 K.AK[136.11]VDLK[136.11]PLLSSLSANK[136.11].E "sp|Q9NRA8|4ET_HUMAN,tr|B1AKL4|B1AKL4_HUMAN,tr|B0QYZ7|B0QYZ7_HUMAN" 3 1707.0357 1.03 88227 20673 4 1707.031195 427.7662 Eukaryotic translation initiation factor 4E transporter OS=Homo sapiens OX=9606 GN=EIF4ENIF1 PE=1 SV=2 9.7 3239.8 - 843086 - - - -2.6221 - 2.591 0.459 - 122 1 2 1 -0.0045 16 0 0 0 2.63E+07 2.57E+07 - - - 3.5553 0.9999 221125_WJC_METTL3_EV_vs_WT_F06.20678.20678.4 5.45E-09 23/108 K.NTKEPPLSLTIHLTSPVVR.E "sp|Q12906|ILF3_HUMAN,tr|K7EQR9|K7EQR9_HUMAN,tr|K7EKY0|K7EKY0_HUMAN,tr|K7EPG3|K7EPG3_HUMAN,tr|K7EKJ9|K7EKJ9_HUMAN" 5 2101.1895 1.07 88229 20678 4 2101.192114 526.3047 Interleukin enhancer-binding factor 3 OS=Homo sapiens OX=9606 GN=ILF3 PE=1 SV=3 8.75 3240.4 - 4.77E+06 - - - 1.2255 - 3.572 0.564 - 517.7 1 2 1 0.0026 19 0 0 0 1.12E+08 1.05E+08 - - - 4.565 0.9986 221125_WJC_METTL3_EV_vs_WT_F06.20680.20680.4 0.00741 13/132 R.TSSIHQLIAPASYSPIQPHSLIK.H "sp|Q8NDX5|PHC3_HUMAN,tr|E7EX82|E7EX82_HUMAN" 2 2487.3486 0.66 88231 20680 4 2487.348996 622.8444 Polyhomeotic-like protein 3 OS=Homo sapiens OX=9606 GN=PHC3 PE=1 SV=1 8.31 3240.7 - 1.14E+06 - - - 0.1757 - 2.642 0.271 - 46.8 1 2 0 0.0004 23 0 0 0 1.54E+07 2.35E+07 - - - 1.8994 1 221125_WJC_METTL3_EV_vs_WT_F06.20683.20683.3 8.16E-13 20/72 K.NTKEPPLSLTIHLTSPVVR.E "sp|Q12906|ILF3_HUMAN,tr|K7EQR9|K7EQR9_HUMAN,tr|K7EKY0|K7EKY0_HUMAN,tr|K7EPG3|K7EPG3_HUMAN,tr|K7EKJ9|K7EKJ9_HUMAN" 5 2101.1895 0.99 88232 20683 3 2101.18856 701.4038 Interleukin enhancer-binding factor 3 OS=Homo sapiens OX=9606 GN=ILF3 PE=1 SV=3 8.75 3241.1 - 1.83E+06 - - - -0.4659 - 3.813 0.611 - 369.3 1 2 1 -0.001 19 0 0 0 3.26E+07 3.27E+07 - - - 8.64 1 221125_WJC_METTL3_EV_vs_WT_F06.20686.20686.3 6.51E-08 20/68 K.EATDPRPC[160.03]EVENAVESWR.T "sp|P47755|CAZA2_HUMAN,tr|C9JUG7|C9JUG7_HUMAN,tr|A0A0D9SET8|A0A0D9SET8_HUMAN,tr|F8W9N7|F8W9N7_HUMAN" 4 2143.9593 1.02 88235 20686 3 2143.961192 715.6604 F-actin-capping protein subunit alpha-2 OS=Homo sapiens OX=9606 GN=CAPZA2 PE=1 SV=3 4.25 3241.4 - 2.12E+06 - - - 0.8909 - 3.014 0.577 - 418.4 1 2 0 0.0019 18 0 0 0 2.68E+07 2.61E+07 - - - 7.7197 0.9999 221125_WJC_METTL3_EV_vs_WT_F06.20688.20688.4 1.29E-05 16/90 K.AKVDLKPLLSSLSANK.E "sp|Q9NRA8|4ET_HUMAN,tr|B1AKL4|B1AKL4_HUMAN,tr|B0QYZ7|B0QYZ7_HUMAN" 3 1682.9931 1.02 88237 20688 4 1682.994113 421.7555 Eukaryotic translation initiation factor 4E transporter OS=Homo sapiens OX=9606 GN=EIF4ENIF1 PE=1 SV=2 9.7 3241.6 - 984846 - - - 0.6191 - 2.825 0.526 - 154.7 1 2 1 0.001 16 0 0 0 2.63E+07 2.57E+07 - - - 4.1698 0.9999 221125_WJC_METTL3_EV_vs_WT_F06.20691.20691.4 2.04E-07 17/84 K.AQNDLIWNIK[136.11]DELK[136.11]K[136.11].V "sp|P09874|PARP1_HUMAN,tr|A0A7I2V5E9|A0A7I2V5E9_HUMAN,tr|A0A7I2V625|A0A7I2V625_HUMAN,tr|A0A7I2V3E1|A0A7I2V3E1_HUMAN" 4 1851.0316 1.02 88238 20691 4 1851.029075 463.7652 Poly [ADP-ribose] polymerase 1 OS=Homo sapiens OX=9606 GN=PARP1 PE=1 SV=4 6.16 3242 - 1.44E+06 - - - -1.39 - 3.185 0.558 - 280.8 1 2 1 -0.0026 15 0 0 0 1.17E+08 1.15E+08 - - - 4.4966 1 221125_WJC_METTL3_EV_vs_WT_F06.20693.20693.4 1.03E-08 22/108 R.NTEIGFLQDALSK[136.11]PHGTVK[136.11].A "sp|Q6PI48|SYDM_HUMAN,tr|A0A3B3IS01|A0A3B3IS01_HUMAN,tr|A0A3B3IS54|A0A3B3IS54_HUMAN,tr|A0A3B3ISK7|A0A3B3ISK7_HUMAN,tr|A0A3B3IT01|A0A3B3IT01_HUMAN,tr|A0A3B3ITS3|A0A3B3ITS3_HUMAN,tr|A0A3B3ITK9|A0A3B3ITK9_HUMAN" 7 2070.1081 0.8 88239 20693 4 2070.105532 518.5343 "Aspartate--tRNA ligase, mitochondrial OS=Homo sapiens OX=9606 GN=DARS2 PE=1 SV=1" 6.75 3242.2 - 1.09E+06 - - - -1.2183 - 3.795 0.589 - 389.5 1 2 0 -0.0025 19 0 0 0 1.34E+07 1.68E+07 - - - 4.8031 1 221125_WJC_METTL3_EV_vs_WT_F06.20695.20695.3 6.18E-11 25/72 K.SVEQQVIGFSGLSDDKNYK.K sp|Q9UL15|BAG5_HUMAN 1 2113.0328 1.16 88241 20695 3 2113.034367 705.3515 BAG family molecular chaperone regulator 5 OS=Homo sapiens OX=9606 GN=BAG5 PE=1 SV=1 4.56 3242.4 - 1.70E+06 - - - 0.7586 - 4.351 0.608 - 573.2 1 2 1 0.0016 19 0 0 0 3.31E+07 2.84E+07 - - - 8.9307 1 221125_WJC_METTL3_EV_vs_WT_F06.20696.20696.3 5.09E-17 26/96 A.YHGDSVASLGTQPDLGSALYQENYK[136.11].Q "sp|Q9HCC0|MCCB_HUMAN,tr|A0A804HJW5|A0A804HJW5_HUMAN,tr|A0A0G2JM88|A0A0G2JM88_HUMAN,tr|A0A804HK37|A0A804HK37_HUMAN,tr|A0A804HIH3|A0A804HIH3_HUMAN,tr|A0A804HKE8|A0A804HKE8_HUMAN,tr|D6RDF7|D6RDF7_HUMAN,tr|A0A804HJ84|A0A804HJ84_HUMAN,tr|A0A804HJW2|A0A804HJW2_HUMAN,tr|A0A804HLJ9|A0A804HLJ9_HUMAN,tr|D6R9R1|D6R9R1_HUMAN,tr|A0A804HHS4|A0A804HHS4_HUMAN,tr|A0A0S2Z5R4|A0A0S2Z5R4_HUMAN" 13 2720.2809 1.04 88242 20696 3 2720.274695 907.7676 "Methylcrotonoyl-CoA carboxylase beta chain, mitochondrial OS=Homo sapiens OX=9606 GN=MCCC2 PE=1 SV=1" 4.54 3242.6 - 1.41E+06 - - - -2.2957 - 5.028 0.711 - 921.5 1 1 0 -0.0062 25 0 0 0 3.60E+07 3.45E+07 - - - 10.1808 0.9997 221125_WJC_METTL3_EV_vs_WT_F06.20697.20697.4 0.00318 14/138 R.ISGETIFVTAPHEATAGIIGVNR[166.11]K[136.11].G "sp|Q00610|CLH1_HUMAN,tr|A0A087WVQ6|A0A087WVQ6_HUMAN" 2 2498.3612 0.84 88243 20697 4 2498.356517 625.5976 Clathrin heavy chain 1 OS=Homo sapiens OX=9606 GN=CLTC PE=1 SV=5 6.76 3242.7 - 1.24E+06 - - - -1.8716 - 2.962 0.372 - 58.6 1 2 0 -0.0047 24 0 0 0 1.88E+07 2.24E+07 - - - 2.8111 1 221125_WJC_METTL3_EV_vs_WT_F06.20698.20698.4 1.09E-07 17/108 R.VNVHGIFSVSSASLVEVHK[136.11].S "sp|P34932|HSP74_HUMAN,tr|A0A087WYC1|A0A087WYC1_HUMAN" 2 2016.0884 0.22 88244 20698 4 2016.093639 505.0294 Heat shock 70 kDa protein 4 OS=Homo sapiens OX=9606 GN=HSPA4 PE=1 SV=4 6.89 3242.8 - 975083 - - - 2.611 - 3.341 0.549 - 266.1 1 2 0 0.0053 19 0 0 0 2.96E+06 1.38E+07 - - - 4.4111 0.9994 221125_WJC_METTL3_EV_vs_WT_F06.20703.20703.4 9.07E-06 15/84 K.AQNDLIWNIKDELKK.V "sp|P09874|PARP1_HUMAN,tr|A0A7I2V5E9|A0A7I2V5E9_HUMAN,tr|A0A7I2V625|A0A7I2V625_HUMAN,tr|A0A7I2V3E1|A0A7I2V3E1_HUMAN" 4 1826.989 1.02 88247 20703 4 1826.992433 457.7545 Poly [ADP-ribose] polymerase 1 OS=Homo sapiens OX=9606 GN=PARP1 PE=1 SV=4 6.16 3243.4 - 1.81E+06 - - - 1.8528 - 3.027 0.41 - 215.9 1 2 1 0.0034 15 0 0 0 1.17E+08 1.15E+08 - - - 3.19 1 221125_WJC_METTL3_EV_vs_WT_F06.20705.20705.3 2.03E-15 23/96 A.YHGDSVASLGTQPDLGSALYQENYK.Q "sp|Q9HCC0|MCCB_HUMAN,tr|A0A804HJW5|A0A804HJW5_HUMAN,tr|A0A0G2JM88|A0A0G2JM88_HUMAN,tr|A0A804HK37|A0A804HK37_HUMAN,tr|A0A804HIH3|A0A804HIH3_HUMAN,tr|A0A804HKE8|A0A804HKE8_HUMAN,tr|D6RDF7|D6RDF7_HUMAN,tr|A0A804HJ84|A0A804HJ84_HUMAN,tr|A0A804HJW2|A0A804HJW2_HUMAN,tr|A0A804HLJ9|A0A804HLJ9_HUMAN,tr|D6R9R1|D6R9R1_HUMAN,tr|A0A804HHS4|A0A804HHS4_HUMAN,tr|A0A0S2Z5R4|A0A0S2Z5R4_HUMAN" 13 2712.2667 1.04 88249 20705 3 2712.270814 905.0962 "Methylcrotonoyl-CoA carboxylase beta chain, mitochondrial OS=Homo sapiens OX=9606 GN=MCCC2 PE=1 SV=1" 4.54 3243.7 - 1.63E+06 - - - 1.5021 - 4.912 0.724 - 643.4 1 1 0 0.0041 25 0 0 0 3.60E+07 3.45E+07 - - - 10.2726 0.9999 221125_WJC_METTL3_EV_vs_WT_F06.20706.20706.4 0.000845 14/138 R.ISGETIFVTAPHEATAGIIGVNRK.G "sp|Q00610|CLH1_HUMAN,tr|A0A087WVQ6|A0A087WVQ6_HUMAN" 2 2480.3387 0.84 88250 20706 4 2480.341741 621.092 Clathrin heavy chain 1 OS=Homo sapiens OX=9606 GN=CLTC PE=1 SV=5 6.76 3243.8 - 1.51E+06 - - - 1.2168 - 2.537 0.4 - 56.1 1 2 0 0.003 24 0 0 0 1.88E+07 2.24E+07 - - - 3.0056 0.9999 221125_WJC_METTL3_EV_vs_WT_F06.20707.20707.3 5.95E-06 14/56 K.AQNDLIWNIK[136.11]DELK[136.11]K[136.11].V "sp|P09874|PARP1_HUMAN,tr|A0A7I2V5E9|A0A7I2V5E9_HUMAN,tr|A0A7I2V625|A0A7I2V625_HUMAN,tr|A0A7I2V3E1|A0A7I2V3E1_HUMAN" 4 1851.0316 1 88251 20707 3 1851.032526 618.0178 Poly [ADP-ribose] polymerase 1 OS=Homo sapiens OX=9606 GN=PARP1 PE=1 SV=4 6.16 3243.9 - 1.15E+06 - - - 0.4743 - 2.767 0.524 - 191.9 1 2 1 0.0009 15 0 0 0 5.49E+07 5.46E+07 - - - 7.0376 1 221125_WJC_METTL3_EV_vs_WT_F06.20710.20710.4 1.95E-09 18/96 R.LASELNHVQEVLEGYKK.K "sp|Q14533|KRT81_HUMAN,sp|A6NCN2|KR87P_HUMAN,sp|P78386|KRT85_HUMAN,sp|O43790|KRT86_HUMAN,sp|P78385|KRT83_HUMAN,tr|A0A087X106|A0A087X106_HUMAN" 6 1956.0316 999 88254 20710 4 1956.031796 490.0152 "Keratin, type II cuticular Hb1 OS=Homo sapiens OX=9606 GN=KRT81 PE=1 SV=3" 5.5 3244.2 - 1.05E+06 - - - 0.0787 - 3.361 0.593 - 268.3 1 2 0 0.0002 17 0 0 0 1.18E+07 0.00E+00 - - - 4.8083 0.9994 221125_WJC_METTL3_EV_vs_WT_F06.20713.20713.4 1.39E-06 15/102 R.NQPDMVELLVHHGADVNR.R "sp|Q9NWX5|ASB6_HUMAN,tr|F6TX30|F6TX30_HUMAN" 2 2042.9956 0.16 88257 20713 4 2043.004222 511.7562 Ankyrin repeat and SOCS box protein 6 OS=Homo sapiens OX=9606 GN=ASB6 PE=1 SV=1 5.21 3244.6 - 546860 - - - 4.2168 - 3.305 0.425 - 217.1 1 2 0 0.0086 18 0 0 0 4.20E+06 2.54E+07 - - - 3.3323 1 221125_WJC_METTL3_EV_vs_WT_F06.20717.20717.3 8.55E-07 16/56 R.NHLLPDIVTC[160.03]VQSSR[166.11].K sp|Q9BSD7|NTPCR_HUMAN 1 1747.8915 1.09 88259 20717 3 1747.894608 583.6378 Cancer-related nucleoside-triphosphatase OS=Homo sapiens OX=9606 GN=NTPCR PE=1 SV=1 6.74 3245.1 - 3.30E+06 - - - 1.7936 - 2.976 0.583 - 490.5 1 2 0 0.0031 15 0 0 0 4.02E+07 3.69E+07 - - - 7.8847 0.9999 221125_WJC_METTL3_EV_vs_WT_F06.20718.20718.3 1.19E-08 17/56 R.NHLLPDIVTC[160.03]VQSSR.K sp|Q9BSD7|NTPCR_HUMAN 1 1737.8832 1.1 88260 20718 3 1737.88934 580.3017 Cancer-related nucleoside-triphosphatase OS=Homo sapiens OX=9606 GN=NTPCR PE=1 SV=1 6.74 3245.1 - 4.61E+06 - - - 3.5313 - 2.989 0.611 - 410.6 1 2 0 0.0061 15 0 0 0 4.02E+07 3.65E+07 - - - 8.2074 0.9998 221125_WJC_METTL3_EV_vs_WT_F06.20719.20719.3 5.55E-09 18/56 K.AQNDLIWNIKDELKK.V "sp|P09874|PARP1_HUMAN,tr|A0A7I2V5E9|A0A7I2V5E9_HUMAN,tr|A0A7I2V625|A0A7I2V625_HUMAN,tr|A0A7I2V3E1|A0A7I2V3E1_HUMAN" 4 1826.989 1 88261 20719 3 1826.994274 610.0036 Poly [ADP-ribose] polymerase 1 OS=Homo sapiens OX=9606 GN=PARP1 PE=1 SV=4 6.16 3245.2 - 2.10E+06 - - - 2.8604 - 3.369 0.565 - 543.8 1 2 1 0.0052 15 0 0 0 5.49E+07 5.46E+07 - - - 8.0071 0.9971 221125_WJC_METTL3_EV_vs_WT_F06.20720.20720.4 5.29E-07 20/126 K.EVFLPSTPGLGMHVEVKDPDGK.V "sp|Q7Z7H5|TMED4_HUMAN,tr|F8W7F7|F8W7F7_HUMAN" 2 2351.1831 0.25 88262 20720 4 2351.194674 588.8031 Transmembrane emp24 domain-containing protein 4 OS=Homo sapiens OX=9606 GN=TMED4 PE=1 SV=1 4.75 3245.2 - 1.19E+06 - - - 4.9086 - 3.097 0.454 - 246.1 1 2 1 0.0115 22 0 0 0 1.79E+07 7.02E+07 - - - 3.5443 1 221125_WJC_METTL3_EV_vs_WT_F06.20721.20721.3 5.28E-05 18/72 K.NAQAIEDMVGYAQETQHEK[136.11].L "sp|Q99460|PSMD1_HUMAN,tr|A0A7I2V4X0|A0A7I2V4X0_HUMAN,tr|A0A7I2V2K8|A0A7I2V2K8_HUMAN,tr|A0A7I2YQY1|A0A7I2YQY1_HUMAN,tr|A0A7I2V523|A0A7I2V523_HUMAN,tr|A0A7I2V641|A0A7I2V641_HUMAN,tr|A0A7I2V491|A0A7I2V491_HUMAN,tr|A0A7I2YQI9|A0A7I2YQI9_HUMAN,tr|A0A7I2V262|A0A7I2V262_HUMAN,tr|A0A087WW66|A0A087WW66_HUMAN,tr|A0A7P0MW50|A0A7P0MW50_HUMAN,tr|A0A7I2V5C8|A0A7I2V5C8_HUMAN,tr|A0A7I2V479|A0A7I2V479_HUMAN" 13 2168.9888 2.44 88263 20721 3 2168.990083 724.0035 26S proteasome non-ATPase regulatory subunit 1 OS=Homo sapiens OX=9606 GN=PSMD1 PE=1 SV=2 4.4 3245.3 - 1.06E+06 - - - 0.5929 - 3.316 0.535 - 375.7 1 2 0 0.0013 19 0 0 0 2.31E+07 9.47E+06 - - - 7.4495 0.9722 221125_WJC_METTL3_EV_vs_WT_F06.20725.20725.3 1.68E-07 18/72 K.TNGLPVQNGIDADVK[136.11]DFSR[166.11].T "sp|Q14671|PUM1_HUMAN,tr|Q5T1Z8|Q5T1Z8_HUMAN,tr|H0YEH2|H0YEH2_HUMAN,tr|Q5T1Z4|Q5T1Z4_HUMAN" 4 2063.0403 0.21 88267 20725 3 2064.034937 688.6874 Pumilio homolog 1 OS=Homo sapiens OX=9606 GN=PUM1 PE=1 SV=3 4.43 3245.8 - 637069 - - - 482.1452 - 3.326 0.502 - 351.5 1 2 1 0.9947 19 0 0 0 5.27E+05 2.49E+06 - - - 6.8138 0.9565 221125_WJC_METTL3_EV_vs_WT_F06.20726.20726.3 0.000113 11/100 K.NGFSSVQATQLQTTQSVEGATGSAVK.S "sp|Q14157|UBP2L_HUMAN,tr|F8W726|F8W726_HUMAN" 2 2595.2776 -1 88268 20726 3 2596.269928 866.0998 Ubiquitin-associated protein 2-like OS=Homo sapiens OX=9606 GN=UBAP2L PE=1 SV=2 6 3246 - 479251 - - - 382.3441 - 2.41 0.398 - 80 1 2 0 0.9923 26 0 0 0 0.00E+00 0.00E+00 - - - 4.7261 0.9994 221125_WJC_METTL3_EV_vs_WT_F06.20727.20727.4 2.80E-05 16/126 R.IHESSPLDLASEEPERLPC[160.03]LQR.L "sp|Q9NWX5|ASB6_HUMAN,tr|F6TX30|F6TX30_HUMAN" 2 2575.2701 2.78 88269 20727 4 2575.275967 644.8248 Ankyrin repeat and SOCS box protein 6 OS=Homo sapiens OX=9606 GN=ASB6 PE=1 SV=1 4.57 3246.1 - 467321 - - - 2.2972 - 2.898 0.43 - 180 1 2 1 0.0059 22 0 0 0 5.61E+06 2.02E+06 - - - 3.3152 1 221125_WJC_METTL3_EV_vs_WT_F06.20730.20730.4 3.63E-07 16/78 K.HTTSIFDDFAHYEK[136.11].R "sp|Q9BYJ9|YTHD1_HUMAN,sp|Q7Z739|YTHD3_HUMAN,tr|A0A087X0Q1|A0A087X0Q1_HUMAN,tr|A0A024R7W5|A0A024R7W5_HUMAN,tr|A0A087WY31|A0A087WY31_HUMAN" 5 1717.7828 1.48 88272 20730 4 1717.783409 430.453 YTH domain-containing family protein 1 OS=Homo sapiens OX=9606 GN=YTHDF1 PE=1 SV=1 5.21 3246.5 - 238471 - - - 0.3836 - 2.677 0.561 - 128.4 1 2 0 0.0007 14 0 0 0 3.18E+07 2.15E+07 - - - 4.4671 0.815 221125_WJC_METTL3_EV_vs_WT_F06.20731.20731.2 1.60E-05 30-Oct K.SKELTTEIDNNIEQIS.S "sp|P13645|K1C10_HUMAN,tr|A0A1B0GVI3|A0A1B0GVI3_HUMAN" 2 1832.9004 1.9 88273 20731 2 1832.904241 917.4575 "Keratin, type I cytoskeletal 10 OS=Homo sapiens OX=9606 GN=KRT10 PE=1 SV=6" 4 3246.6 - 176622 - - - 2.1212 - 2.369 0.476 - 260.3 1 1 1 0.0039 16 0 0 0 2.97E+06 1.56E+06 - - - 4.6759 1 221125_WJC_METTL3_EV_vs_WT_F06.20733.20733.3 1.42E-06 17/104 R.IGQELLFPPQENVQDAGAPGGHTQNLR.C sp|Q5JSZ5|PRC2B_HUMAN 1 2885.442 2.83 88274 20733 3 2885.449912 962.8213 Protein PRRC2B OS=Homo sapiens OX=9606 GN=PRRC2B PE=1 SV=2 4.65 3247 - 675647 - - - 2.7355 - 3.735 0.581 - 133 1 2 0 0.0079 27 0 0 0 1.80E+07 6.36E+06 - - - 8.0471 1 221125_WJC_METTL3_EV_vs_WT_F06.20735.20735.3 4.15E-12 18/68 K.YVHYEIDAC[160.03]MDSEAPGSK[136.11].D "sp|Q86U44|MTA70_HUMAN,tr|H0YFV6|H0YFV6_HUMAN" 2 2078.8805 0.01 88275 20735 3 2079.884334 693.9674 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 4.31 3247.2 - 1.61E+06 - - - 482.8762 - 3.518 0.661 - 358.6 1 2 0 1.0038 18 0 0 0 8.39E+05 6.12E+07 - - - 8.7637 1 221125_WJC_METTL3_EV_vs_WT_F06.20737.20737.3 1.36E-13 19/52 K.HTTSIFDDFAHYEK[136.11].R "sp|Q9BYJ9|YTHD1_HUMAN,sp|Q7Z739|YTHD3_HUMAN,tr|A0A087X0Q1|A0A087X0Q1_HUMAN,tr|A0A024R7W5|A0A024R7W5_HUMAN,tr|A0A087WY31|A0A087WY31_HUMAN" 5 1717.7828 1.43 88277 20737 3 1717.78622 573.6015 YTH domain-containing family protein 1 OS=Homo sapiens OX=9606 GN=YTHDF1 PE=1 SV=1 5.21 3247.3 - 3.83E+06 - - - 2.02 - 3.473 0.681 - 329.6 1 2 0 0.0035 14 0 0 0 1.30E+08 9.11E+07 - - - 9.4402 1 221125_WJC_METTL3_EV_vs_WT_F06.20740.20740.3 1.47E-08 25/72 K.K[136.11]GIVDQSQQAYQEAFEISK[136.11].K "sp|P63104|1433Z_HUMAN,tr|H0YB80|H0YB80_HUMAN,tr|B7Z2E6|B7Z2E6_HUMAN,tr|B0AZS6|B0AZS6_HUMAN" 4 2184.1034 1.15 88280 20740 3 2184.10228 729.0417 14-3-3 protein zeta\delta OS=Homo sapiens OX=9606 GN=YWHAZ PE=1 SV=1 4.68 3247.6 - 1.57E+06 - - - -0.4959 - 4.768 0.626 - 1211.2 1 2 0 -0.0011 19 0 0 0 2.11E+07 1.83E+07 - - - 9.3563 0.9998 221125_WJC_METTL3_EV_vs_WT_F06.20742.20742.4 8.55E-12 21/120 K.VIETNRENDKQETWMLMELQK.L sp|P15924|DESP_HUMAN 1 2634.2782 61.69 88282 20742 4 2634.285509 659.5768 Desmoplakin OS=Homo sapiens OX=9606 GN=DSP PE=1 SV=3 4.59 3247.8 - 1.28E+06 - - - 2.7848 - 3.409 0.602 - 240.5 1 2 2 0.0073 21 0 0 0 3.77E+07 6.11E+05 - - - 4.8693 1 221125_WJC_METTL3_EV_vs_WT_F06.20743.20743.4 6.76E-11 19/78 K.HTTSIFDDFAHYEK.R "sp|Q9BYJ9|YTHD1_HUMAN,sp|Q7Z739|YTHD3_HUMAN,tr|A0A087X0Q1|A0A087X0Q1_HUMAN,tr|A0A024R7W5|A0A024R7W5_HUMAN,tr|A0A087WY31|A0A087WY31_HUMAN" 5 1709.7686 1.48 88283 20743 4 1709.770836 428.4494 YTH domain-containing family protein 1 OS=Homo sapiens OX=9606 GN=YTHDF1 PE=1 SV=1 5.21 3247.9 - 1.28E+06 - - - 1.337 - 3.187 0.634 - 216.7 1 2 0 0.0023 14 0 0 0 3.18E+07 2.15E+07 - - - 5.1655 1 221125_WJC_METTL3_EV_vs_WT_F06.20744.20744.3 1.64E-11 23/72 K.KGIVDQSQQAYQEAFEISK.K "sp|P63104|1433Z_HUMAN,tr|H0YB80|H0YB80_HUMAN,tr|B7Z2E6|B7Z2E6_HUMAN,tr|B0AZS6|B0AZS6_HUMAN" 4 2168.075 1.15 88284 20744 3 2168.079992 723.6989 14-3-3 protein zeta\delta OS=Homo sapiens OX=9606 GN=YWHAZ PE=1 SV=1 4.68 3248 - 953691 - - - 2.3196 - 4.813 0.593 - 1142.1 1 2 0 0.005 19 0 0 0 2.11E+07 1.83E+07 - - - 9.0104 0.9999 221125_WJC_METTL3_EV_vs_WT_F06.20745.20745.4 0.000705 17/108 K.NFTEVHPDYGSHIQALLDK.Y sp|P04040|CATA_HUMAN 1 2183.0647 10.71 88285 20745 4 2183.064712 546.7735 Catalase OS=Homo sapiens OX=9606 GN=CAT PE=1 SV=3 5.21 3248.1 - 933724 - - - -0.0096 - 2.986 0.401 - 177.9 1 2 0 0 19 0 0 0 1.79E+07 1.67E+06 - - - 3.0864 0.9999 221125_WJC_METTL3_EV_vs_WT_F06.20746.20746.3 0.00926 15/44 R.FATSEELLSHLR.T "sp|Q9H7S9|ZN703_HUMAN,sp|Q96F45|ZN503_HUMAN" 2 1401.7252 1.33 88286 20746 3 1401.727712 468.249 Zinc finger protein 703 OS=Homo sapiens OX=9606 GN=ZNF703 PE=1 SV=1 5.4 3248.2 - 833637 - - - 1.7714 - 2.398 0.432 - 180.5 1 2 0 0.0025 12 0 0 0 6.55E+06 4.91E+06 - - - 5.78 1 221125_WJC_METTL3_EV_vs_WT_F06.20749.20749.3 1.47E-08 14/104 R.IGQELLFPPQENVQDAGAPGGHTQNLR[166.11].C sp|Q5JSZ5|PRC2B_HUMAN 1 2895.4503 2.79 88289 20749 3 2895.453677 966.1574 Protein PRRC2B OS=Homo sapiens OX=9606 GN=PRRC2B PE=1 SV=2 4.65 3248.6 - 375601 - - - 1.1701 - 2.772 0.576 - 96.1 1 2 0 0.0034 27 0 0 0 2.24E+07 8.05E+06 - - - 7.3065 1 221125_WJC_METTL3_EV_vs_WT_F06.20752.20752.3 5.40E-10 18/52 K.HTTSIFDDFAHYEK.R "sp|Q9BYJ9|YTHD1_HUMAN,sp|Q7Z739|YTHD3_HUMAN,tr|A0A087X0Q1|A0A087X0Q1_HUMAN,tr|A0A024R7W5|A0A024R7W5_HUMAN,tr|A0A087WY31|A0A087WY31_HUMAN" 5 1709.7686 1.42 88290 20752 3 1709.773072 570.9301 YTH domain-containing family protein 1 OS=Homo sapiens OX=9606 GN=YTHDF1 PE=1 SV=1 5.21 3249 - 1.05E+07 - - - 2.6448 - 3.538 0.671 - 317.9 1 2 0 0.0045 14 0 0 0 1.30E+08 9.13E+07 - - - 9.3777 1 221125_WJC_METTL3_EV_vs_WT_F06.20754.20754.3 5.69E-11 23/88 R.ALQSGQC[160.03]AGAALDVFTEEPPRDR.A "sp|O43175|SERA_HUMAN,tr|A0A286YF78|A0A286YF78_HUMAN,tr|A0A2C9F2M7|A0A2C9F2M7_HUMAN,tr|A0A286YF22|A0A286YF22_HUMAN,tr|A0A286YFL2|A0A286YFL2_HUMAN,tr|A0A286YFA2|A0A286YFA2_HUMAN" 6 2487.1812 3.33 88292 20754 3 2487.184714 830.0677 D-3-phosphoglycerate dehydrogenase OS=Homo sapiens OX=9606 GN=PHGDH PE=1 SV=4 4.32 3249.2 - 1.74E+06 - - - 1.3984 - 4.273 0.634 - 635.9 1 2 1 0.0035 23 0 0 0 1.20E+07 3.61E+06 - - - 9.0146 0.9997 221125_WJC_METTL3_EV_vs_WT_F06.20760.20760.4 0.000138 13/144 R.DSTGIVTPSGTFHQHVPAGYMDFPK[136.11].V "sp|O75179|ANR17_HUMAN,tr|H0YM23|H0YM23_HUMAN" 2 2696.2784 3.67 88298 20760 4 2696.279087 675.0769 Ankyrin repeat domain-containing protein 17 OS=Homo sapiens OX=9606 GN=ANKRD17 PE=1 SV=3 5.98 3249.9 - 423666 - - - 0.2411 - 2.954 0.348 - 80.5 1 2 0 0.0006 25 0 0 0 7.59E+06 2.06E+06 - - - 2.5994 0.9999 221125_WJC_METTL3_EV_vs_WT_F06.20766.20766.3 6.87E-07 17/80 K.VIETNRENDKQETWMLMELQK.L sp|P15924|DESP_HUMAN 1 2634.2782 999 88302 20766 3 2634.282116 879.1 Desmoplakin OS=Homo sapiens OX=9606 GN=DSP PE=1 SV=3 4.59 3250.7 - 969586 - - - 1.4968 - 3.828 0.551 - 273.6 1 2 2 0.0039 21 0 0 0 6.69E+06 0.00E+00 - - - 7.9002 0.922 221125_WJC_METTL3_EV_vs_WT_F06.20767.20767.3 0.000494 Nov-64 K.R[166.11]R[166.11]AEQDSTTVAAFASSL.V "sp|Q86U44|MTA70_HUMAN,tr|F5H6D8|F5H6D8_HUMAN,tr|H0YFV6|H0YFV6_HUMAN,tr|B4DTN4|B4DTN4_HUMAN" 4 1828.9182 0.01 88303 20767 3 1828.921663 610.6467 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 6.07 3250.7 - 6.53E+06 - - - 1.8771 - 2.304 0.41 - 134 1 1 1 0.0034 17 0 0 0 6.79E+06 7.24E+08 - - - 5.2187 0.9993 221125_WJC_METTL3_EV_vs_WT_F06.20770.20770.3 1.86E-06 16/60 K.FR[166.11]QDLMNIAGTTLSSK[136.11].L "sp|P78371|TCPB_HUMAN,tr|F8VQ14|F8VQ14_HUMAN,tr|F5GWF6|F5GWF6_HUMAN" 3 1798.9366 2.57 88306 20770 3 1798.944066 600.6528 T-complex protein 1 subunit beta OS=Homo sapiens OX=9606 GN=CCT2 PE=1 SV=4 8.75 3251 - 931461 - - - 4.1286 - 3.04 0.537 - 383.2 1 2 1 0.0074 16 0 0 0 2.56E+07 9.98E+06 - - - 7.3778 1 221125_WJC_METTL3_EV_vs_WT_F06.20771.20771.3 2.46E-12 17/96 K.LVQDVANNTNEEAGDGTTTATVLAR.S "sp|P10809|CH60_HUMAN,tr|C9JL25|C9JL25_HUMAN,tr|A0A7I2V2X6|A0A7I2V2X6_HUMAN,tr|A0A7I2YQK6|A0A7I2YQK6_HUMAN,tr|A0A7I2V599|A0A7I2V599_HUMAN,tr|E7EXB4|E7EXB4_HUMAN,tr|A0A7I2YQ71|A0A7I2YQ71_HUMAN,tr|E7ESH4|E7ESH4_HUMAN,tr|A0A7I2V5M1|A0A7I2V5M1_HUMAN,tr|A0A7I2V5K3|A0A7I2V5K3_HUMAN,tr|A0A7I2V369|A0A7I2V369_HUMAN" 11 2559.2413 2.06 88307 20771 3 2559.247427 854.0877 "60 kDa heat shock protein, mitochondrial OS=Homo sapiens OX=9606 GN=HSPD1 PE=1 SV=2" 3.92 3251.2 - 595165 - - - 2.4124 - 3.513 0.659 - 324.9 1 2 0 0.0062 25 0 0 0 6.13E+06 2.98E+06 - - - 8.7762 0.9999 221125_WJC_METTL3_EV_vs_WT_F06.20772.20772.3 0.0022 17/68 R.EHLGHESDNLLFVQITGK.K "sp|Q6FI81|CPIN1_HUMAN,tr|H3BV90|H3BV90_HUMAN,tr|H3BUG4|H3BUG4_HUMAN,tr|H3BPG7|H3BPG7_HUMAN,tr|H3BT65|H3BT65_HUMAN" 5 2036.0327 21.71 88308 20772 3 2036.038152 679.6848 Anamorsin OS=Homo sapiens OX=9606 GN=CIAPIN1 PE=1 SV=2 5.28 3251.3 - 440259 - - - 2.6758 - 3.155 0.445 - 340.2 1 2 0 0.0054 18 0 0 0 7.94E+07 3.66E+06 - - - 6.3609 1 221125_WJC_METTL3_EV_vs_WT_F06.20775.20775.2 5.48E-12 15/34 R.DSSTC[160.03]PGDYVLSVSENSR[166.11].V sp|P46109|CRKL_HUMAN 1 1981.8563 0.49 88311 20775 2 1981.85511 991.9354 Crk-like protein OS=Homo sapiens OX=9606 GN=CRKL PE=1 SV=1 4.03 3251.7 - 297833 - - - -0.5853 - 2.792 0.732 - 494.1 1 2 0 -0.0012 18 0 0 0 4.78E+06 9.65E+06 - - - 6.9715 0.9999 221125_WJC_METTL3_EV_vs_WT_F06.20779.20779.3 4.07E-07 13/64 R.GAPPSSNIEDFHGLLPK.G "sp|P43243|MATR3_HUMAN,tr|A8MXP9|A8MXP9_HUMAN,tr|D6R991|D6R991_HUMAN,tr|A0A0R4J2E8|A0A0R4J2E8_HUMAN,tr|H0Y8T4|H0Y8T4_HUMAN,tr|D6REM6|D6REM6_HUMAN" 6 1777.8999 1.33 88314 20779 3 1777.903714 593.6406 Matrin-3 OS=Homo sapiens OX=9606 GN=MATR3 PE=1 SV=2 5.32 3252.2 - 5.45E+06 - - - 2.1458 - 2.596 0.527 - 159.3 1 2 0 0.0038 17 0 0 0 1.16E+08 8.73E+07 - - - 6.8245 1 221125_WJC_METTL3_EV_vs_WT_F06.20788.20788.3 2.59E-11 26/108 K.AAPTPTPAPVPVPVPLPAPAPAPHGEAR.L sp|Q96T58|MINT_HUMAN 1 2674.4595 2.68 88322 20788 3 2674.474661 892.4938 Msx2-interacting protein OS=Homo sapiens OX=9606 GN=SPEN PE=1 SV=1 6.79 3253.1 - 552542 - - - 5.6662 - 4.391 0.636 - 475.7 1 2 0 0.0152 28 0 0 0 1.63E+06 6.09E+05 - - - 9.0305 1 221125_WJC_METTL3_EV_vs_WT_F06.20789.20789.3 1.60E-11 17/96 K.LVQDVANNTNEEAGDGTTTATVLAR[166.11].S "sp|P10809|CH60_HUMAN,tr|C9JL25|C9JL25_HUMAN,tr|A0A7I2V2X6|A0A7I2V2X6_HUMAN,tr|A0A7I2YQK6|A0A7I2YQK6_HUMAN,tr|A0A7I2V599|A0A7I2V599_HUMAN,tr|E7EXB4|E7EXB4_HUMAN,tr|A0A7I2YQ71|A0A7I2YQ71_HUMAN,tr|E7ESH4|E7ESH4_HUMAN,tr|A0A7I2V5M1|A0A7I2V5M1_HUMAN,tr|A0A7I2V5K3|A0A7I2V5K3_HUMAN,tr|A0A7I2V369|A0A7I2V369_HUMAN" 11 2569.2495 3.23 88323 20789 3 2569.248072 857.4238 "60 kDa heat shock protein, mitochondrial OS=Homo sapiens OX=9606 GN=HSPD1 PE=1 SV=2" 3.92 3253.2 - 368925 - - - -0.5648 - 3.282 0.62 - 312.4 1 2 0 -0.0015 25 0 0 0 1.51E+07 4.67E+06 - - - 8.1862 0.9983 221125_WJC_METTL3_EV_vs_WT_F06.20790.20790.3 6.28E-05 Dec-76 R.VINEPTAAALAYGLDK[136.11]SEDK[136.11].V "sp|P38646|GRP75_HUMAN,tr|H0Y8K0|H0Y8K0_HUMAN,tr|A0A7I2V2S7|A0A7I2V2S7_HUMAN,tr|A0A7I2V2G2|A0A7I2V2G2_HUMAN,tr|A0A7I2V3F7|A0A7I2V3F7_HUMAN,tr|A0A7I2YQB2|A0A7I2YQB2_HUMAN,tr|D6RCD7|D6RCD7_HUMAN" 7 2120.0972 0.14 88324 20790 3 2120.101465 707.7063 "Stress-70 protein, mitochondrial OS=Homo sapiens OX=9606 GN=HSPA9 PE=1 SV=2" 4.32 3253.4 - 324851 - - - 2.0046 - 2.256 0.366 - 131.3 1 2 1 0.0043 20 0 0 0 3.20E+05 2.28E+06 - - - 4.5932 0.9996 221125_WJC_METTL3_EV_vs_WT_F06.20794.20794.2 1.63E-05 18-Nov K.FAAQELIEVK[136.11].R "sp|Q86U44|MTA70_HUMAN,tr|F5H6D8|F5H6D8_HUMAN,tr|H0YFV6|H0YFV6_HUMAN,tr|B4DTN4|B4DTN4_HUMAN" 4 1154.6427 0.02 88327 20794 2 1154.644743 578.3286 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 4.53 3253.9 - 1.69E+07 - - - 1.791 - 2.032 0.441 - 341.5 1 2 0 0.0021 10 0 0 0 1.18E+07 5.01E+08 - - - 4.2767 0.905 221125_WJC_METTL3_EV_vs_WT_F06.20796.20796.2 2.10E-05 13/32 K.R[166.11]R[166.11]AEQDSTTVAAFASSL.V "sp|Q86U44|MTA70_HUMAN,tr|F5H6D8|F5H6D8_HUMAN,tr|H0YFV6|H0YFV6_HUMAN,tr|B4DTN4|B4DTN4_HUMAN" 4 1828.9182 0.001 88329 20796 2 1828.918437 915.4664 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 6.07 3254 - 2.31E+06 - - - 0.1132 - 1.966 0.507 - 103.9 1 1 1 0.0002 17 0 0 0 0.00E+00 5.58E+07 - - - 4.4476 0.9999 221125_WJC_METTL3_EV_vs_WT_F06.20797.20797.3 1.51E-07 19/68 R.ASWESLDEEWRAPQAGSR.T sp|Q00587|BORG5_HUMAN 1 2073.9504 1.26 88330 20797 3 2073.954692 692.3241 Cdc42 effector protein 1 OS=Homo sapiens OX=9606 GN=CDC42EP1 PE=1 SV=1 4.41 3254.1 - 1.98E+06 - - - 2.0545 - 3.214 0.611 - 386.2 1 2 1 0.0043 18 0 0 0 2.80E+07 2.21E+07 - - - 8.2581 0.9997 221125_WJC_METTL3_EV_vs_WT_F06.20798.20798.3 2.27E-07 16/68 R.ASWESLDEEWR[166.11]APQAGSR[166.11].T sp|Q00587|BORG5_HUMAN 1 2093.967 1.26 88331 20798 3 2093.970885 698.9963 Cdc42 effector protein 1 OS=Homo sapiens OX=9606 GN=CDC42EP1 PE=1 SV=1 4.41 3254.2 - 1.85E+06 - - - 1.8692 - 2.557 0.5 - 246 1 2 1 0.0039 18 0 0 0 2.80E+07 2.21E+07 - - - 6.4512 1 221125_WJC_METTL3_EV_vs_WT_F06.20799.20799.3 2.58E-08 26/84 K.RVIISAPSADAPMFVMGVNHEK.Y "sp|P04406|G3P_HUMAN,tr|E7EUT5|E7EUT5_HUMAN" 2 2368.2032 1.06 88332 20799 3 2368.206981 790.4083 Glyceraldehyde-3-phosphate dehydrogenase OS=Homo sapiens OX=9606 GN=GAPDH PE=1 SV=3 6.75 3254.3 - 1.22E+06 - - - 1.6147 - 4.291 0.649 - 718.7 1 2 0 0.0038 22 0 0 0 2.64E+07 2.49E+07 - - - 9.2278 1 221125_WJC_METTL3_EV_vs_WT_F06.20800.20800.3 3.12E-06 14/64 R.NNQGQLIAEPFYHLPSK[136.11].K "sp|Q86U86|PB1_HUMAN,tr|H0Y5B5|H0Y5B5_HUMAN,tr|E7EVG2|E7EVG2_HUMAN" 3 1963.0043 1.64 88333 20800 3 1963.00595 655.342 Protein polybromo-1 OS=Homo sapiens OX=9606 GN=PBRM1 PE=1 SV=1 6.75 3254.4 - 1.12E+06 - - - 0.8349 - 2.601 0.455 - 282 1 2 0 0.0016 17 0 0 0 1.52E+07 9.24E+06 - - - 6.0272 0.9998 221125_WJC_METTL3_EV_vs_WT_F06.20801.20801.3 1.66E-06 28/84 R.EQQIVIQSSGGLSKDDIENMVK.N "sp|P38646|GRP75_HUMAN,tr|A0A7I2V2S7|A0A7I2V2S7_HUMAN,tr|A0A7I2V2G2|A0A7I2V2G2_HUMAN,tr|H0Y8S0|H0Y8S0_HUMAN,tr|A0A7I2V3F7|A0A7I2V3F7_HUMAN,tr|A0A7I2YQB2|A0A7I2YQB2_HUMAN,tr|D6RCD7|D6RCD7_HUMAN" 7 2417.2108 0.42 88334 20801 3 2417.216832 806.7442 "Stress-70 protein, mitochondrial OS=Homo sapiens OX=9606 GN=HSPA9 PE=1 SV=2" 4.32 3254.5 - 780281 - - - 2.4934 - 4.071 0.532 - 755.9 1 2 1 0.006 22 0 0 0 1.03E+08 2.44E+08 - - - 7.798 0.995 221125_WJC_METTL3_EV_vs_WT_F06.20802.20802.4 0.0078 14/102 R.EHLGHESDNLLFVQITGK[136.11].K "sp|Q6FI81|CPIN1_HUMAN,tr|H3BV90|H3BV90_HUMAN,tr|H3BUG4|H3BUG4_HUMAN,tr|H3BPG7|H3BPG7_HUMAN,tr|H3BT65|H3BT65_HUMAN" 5 2044.0469 0.45 88335 20802 4 2044.057777 512.019 Anamorsin OS=Homo sapiens OX=9606 GN=CIAPIN1 PE=1 SV=2 5.28 3254.6 - 774364 - - - 5.3193 - 2.546 0.352 - 154.9 1 2 0 0.0109 18 0 0 0 3.13E+06 6.92E+06 - - - 2.6069 0.8766 221125_WJC_METTL3_EV_vs_WT_F06.20806.20806.3 0.00269 Sep-64 K.VTEGLTDVILYHQPDDK.K "sp|O60506|HNRPQ_HUMAN,tr|A0A7I2YQV8|A0A7I2YQV8_HUMAN,tr|A0A7I2YQN2|A0A7I2YQN2_HUMAN,tr|A0A7I2V5Q6|A0A7I2V5Q6_HUMAN,tr|A0A7I2V4Z0|A0A7I2V4Z0_HUMAN,tr|B7Z645|B7Z645_HUMAN,tr|A0A7I2V2F2|A0A7I2V2F2_HUMAN,tr|A0A7I2V346|A0A7I2V346_HUMAN,tr|A0A7I2V309|A0A7I2V309_HUMAN" 9 1941.9684 1.84 88339 20806 3 1941.981822 648.3301 Heterogeneous nuclear ribonucleoprotein Q OS=Homo sapiens OX=9606 GN=SYNCRIP PE=1 SV=2 4.22 3255.1 - 279795 - - - 6.9254 - 2.126 0.201 - 79.4 1 2 0 0.0134 17 0 0 0 2.00E+06 1.09E+06 - - - 2.6827 1 221125_WJC_METTL3_EV_vs_WT_F06.20810.20810.3 1.33E-08 20/72 R.KDGLVSLLTTSEGADEPQR.L "sp|P51570|GALK1_HUMAN,tr|K7ERJ9|K7ERJ9_HUMAN,tr|K7ERN9|K7ERN9_HUMAN,tr|K7EII7|K7EII7_HUMAN" 4 2015.0171 1.79 88341 20810 3 2015.019852 672.6796 Galactokinase OS=Homo sapiens OX=9606 GN=GALK1 PE=1 SV=1 4.32 3255.6 - 4.55E+06 - - - 1.3588 - 3.338 0.628 - 494.6 1 2 0 0.0027 19 0 0 0 4.93E+08 2.75E+08 - - - 8.5022 0.9999 221125_WJC_METTL3_EV_vs_WT_F06.20811.20811.4 2.23E-09 22/126 K.RVIISAPSADAPMFVMGVNHEK.Y "sp|P04406|G3P_HUMAN,tr|E7EUT5|E7EUT5_HUMAN" 2 2368.2032 1.07 88342 20811 4 2368.210906 593.0581 Glyceraldehyde-3-phosphate dehydrogenase OS=Homo sapiens OX=9606 GN=GAPDH PE=1 SV=3 6.75 3255.6 - 5.11E+06 - - - 3.2721 - 3.792 0.597 - 302 1 2 0 0.0077 22 0 0 0 7.32E+07 6.81E+07 - - - 4.8563 1 221125_WJC_METTL3_EV_vs_WT_F06.20812.20812.4 9.18E-08 25/138 K.DVIGIAHHPHQNLIATYSEDGLLK[136.11].L sp|Q2TAY7|SMU1_HUMAN 1 2648.3802 1.04 88343 20812 4 2648.383169 663.1023 WD40 repeat-containing protein SMU1 OS=Homo sapiens OX=9606 GN=SMU1 PE=1 SV=2 5.73 3255.7 - 3.58E+06 - - - 1.1211 - 3.867 0.496 - 443.1 1 2 0 0.003 24 0 0 0 6.60E+07 6.34E+07 - - - 3.9765 1 221125_WJC_METTL3_EV_vs_WT_F06.20813.20813.3 7.99E-10 19/72 R.K[136.11]DGLVSLLTTSEGADEPQR[166.11].L "sp|P51570|GALK1_HUMAN,tr|K7ERJ9|K7ERJ9_HUMAN,tr|K7ERN9|K7ERN9_HUMAN,tr|K7EII7|K7EII7_HUMAN" 4 2033.0396 1.78 88344 20813 3 2033.042725 678.6871 Galactokinase OS=Homo sapiens OX=9606 GN=GALK1 PE=1 SV=1 4.32 3255.8 - 2.68E+06 - - - 1.545 - 3.492 0.647 - 396.6 1 2 0 0.0031 19 0 0 0 4.93E+08 2.76E+08 - - - 8.8247 1 221125_WJC_METTL3_EV_vs_WT_F06.20815.20815.2 3.55E-10 14/34 R.DSSTC[160.03]PGDYVLSVSENSR.V sp|P46109|CRKL_HUMAN 1 1971.848 0.49 88346 20815 2 1971.849609 986.9313 Crk-like protein OS=Homo sapiens OX=9606 GN=CRKL PE=1 SV=1 4.03 3256 - 393453 - - - 0.816 - 2.781 0.751 - 453.2 1 2 0 0.0016 18 0 0 0 4.78E+06 9.65E+06 - - - 7.102 0.9998 221125_WJC_METTL3_EV_vs_WT_F06.20818.20818.3 2.73E-07 16/52 K.NKLNDLEDALQQAK.E sp|P04264|K2C1_HUMAN 1 1598.8264 999 88348 20818 3 1598.829513 533.9494 "Keratin, type II cytoskeletal 1 OS=Homo sapiens OX=9606 GN=KRT1 PE=1 SV=6" 4.56 3256.4 - 1.75E+06 - - - 1.9471 - 3.341 0.495 - 458.4 1 2 1 0.0031 14 0 0 0 4.98E+07 0.00E+00 - - - 7.2636 1 221125_WJC_METTL3_EV_vs_WT_F06.20820.20820.4 2.26E-10 23/138 K.DVIGIAHHPHQNLIATYSEDGLLK.L sp|Q2TAY7|SMU1_HUMAN 1 2640.366 1.03 88349 20820 4 2640.370612 661.0988 WD40 repeat-containing protein SMU1 OS=Homo sapiens OX=9606 GN=SMU1 PE=1 SV=2 5.73 3256.6 - 3.96E+06 - - - 1.7467 - 4.006 0.582 - 401.3 1 2 0 0.0046 24 0 0 0 6.52E+07 6.34E+07 - - - 4.7359 0.9624 221125_WJC_METTL3_EV_vs_WT_F06.20822.20822.3 6.17E-05 14/64 K.R[166.11]RAEQDSTTVAAFASSL.V "sp|Q86U44|MTA70_HUMAN,tr|F5H6D8|F5H6D8_HUMAN,tr|H0YFV6|H0YFV6_HUMAN,tr|B4DTN4|B4DTN4_HUMAN" 4 1818.91 - 88351 20822 3 1818.910394 607.3106 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 6.07 3256.8 - 2.57E+06 - - - 0.2386 - 2.444 0.413 - 222.8 1 1 1 0.0004 17 0 0 0 - - - - - 5.402 0.9979 221125_WJC_METTL3_EV_vs_WT_F06.20823.20823.3 5.71E-07 19/96 R.AAASSYNTQGAASSLGSYGAQAASY.G sp|Q96PK6|RBM14_HUMAN 1 2353.0458 - 88352 20823 3 2353.047013 785.3559 RNA-binding protein 14 OS=Homo sapiens OX=9606 GN=RBM14 PE=1 SV=2 5.57 3256.9 - 1.28E+06 - - - 0.4951 - 3.522 0.503 - 298.7 1 1 0 0.0012 25 0 0 0 - - - - - 7.0442 0.9999 221125_WJC_METTL3_EV_vs_WT_F06.20824.20824.4 4.51E-06 22/90 K.FWDFELVK[136.11]DENSTQK[136.11]R[166.11].L sp|Q9UNX4|WDR3_HUMAN 1 2067.0272 1.03 88353 20824 4 2067.02596 517.7641 WD repeat-containing protein 3 OS=Homo sapiens OX=9606 GN=WDR3 PE=1 SV=1 4.78 3257 - 917334 - - - -0.5878 - 3.651 0.537 - 424.9 1 2 1 -0.0012 16 0 0 0 1.06E+07 1.02E+07 - - - 4.3559 1 221125_WJC_METTL3_EV_vs_WT_F06.20826.20826.3 1.14E-09 21/80 K.ADRDESSPYAAMLAAQDVAQR.C "sp|P62263|RS14_HUMAN,tr|A0A2R8Y811|A0A2R8Y811_HUMAN,tr|E5RH77|E5RH77_HUMAN" 3 2264.0492 1.36 88355 20826 3 2264.051851 755.6903 40S ribosomal protein S14 OS=Homo sapiens OX=9606 GN=RPS14 PE=1 SV=3 4.23 3257.2 - 520575 - - - 1.189 - 3.834 0.615 - 658.5 1 2 1 0.0027 21 0 0 0 6.60E+09 4.83E+09 - - - 8.6179 1 221125_WJC_METTL3_EV_vs_WT_F06.20829.20829.2 1.10E-07 Dec-48 R.AAASSYNTQGAASSLGSYGAQAASY.G sp|Q96PK6|RBM14_HUMAN 1 2353.0458 - 88358 20829 2 2353.044827 1177.5302 RNA-binding protein 14 OS=Homo sapiens OX=9606 GN=RBM14 PE=1 SV=2 5.57 3257.6 - 285831 - - - -0.4339 - 2.393 0.675 - 248.9 1 1 0 -0.001 25 0 0 0 - - - - - 6.1714 0.9994 221125_WJC_METTL3_EV_vs_WT_F06.20838.20838.4 5.21E-06 14/90 K.FWDFELVKDENSTQKR.L sp|Q9UNX4|WDR3_HUMAN 1 2040.9905 1.02 88365 20838 4 2040.990548 511.2549 WD repeat-containing protein 3 OS=Homo sapiens OX=9606 GN=WDR3 PE=1 SV=1 4.78 3258.5 - 1.05E+06 - - - 0.0211 - 3.102 0.379 - 169.1 1 2 1 0 16 0 0 0 1.04E+07 1.02E+07 - - - 2.9236 1 221125_WJC_METTL3_EV_vs_WT_F06.20839.20839.3 2.14E-11 22/80 K.ADR[166.11]DESSPYAAMLAAQDVAQR[166.11].C "sp|P62263|RS14_HUMAN,tr|A0A2R8Y811|A0A2R8Y811_HUMAN,tr|E5RH77|E5RH77_HUMAN" 3 2284.0657 1.36 88366 20839 3 2284.065121 762.3625 40S ribosomal protein S14 OS=Homo sapiens OX=9606 GN=RPS14 PE=1 SV=3 4.23 3258.6 - 1.01E+06 - - - -0.2531 - 4.143 0.664 - 624.3 1 2 1 -0.0006 21 0 0 0 6.59E+09 4.83E+09 - - - 9.3506 1 221125_WJC_METTL3_EV_vs_WT_F06.20848.20848.3 1.66E-09 22/84 K.SDQLLSSNENFTNK[136.11]VNENELLR[166.11].Q "sp|Q15643|TRIPB_HUMAN,tr|H0YJ97|H0YJ97_HUMAN" 2 2581.2739 1.16 88373 20848 3 2581.269208 861.4319 Thyroid receptor-interacting protein 11 OS=Homo sapiens OX=9606 GN=TRIP11 PE=1 SV=3 4.41 3259.6 - 3.08E+06 - - - -1.8154 - 4.488 0.684 - 503.2 1 2 1 -0.0047 22 0 0 0 4.81E+07 4.13E+07 - - - 9.7242 1 221125_WJC_METTL3_EV_vs_WT_F06.20852.20852.2 1.65E-15 20/36 R.KDGLVSLLTTSEGADEPQR.L "sp|P51570|GALK1_HUMAN,tr|K7ERJ9|K7ERJ9_HUMAN,tr|K7ERN9|K7ERN9_HUMAN,tr|K7EII7|K7EII7_HUMAN" 4 2015.0171 2.08 88377 20852 2 2015.014347 1008.5158 Galactokinase OS=Homo sapiens OX=9606 GN=GALK1 PE=1 SV=1 4.32 3260.1 - 580586 - - - -1.3732 - 4.123 0.746 - 964.1 1 2 0 -0.0028 19 0 0 0 1.64E+07 7.89E+06 - - - 8.0328 1 221125_WJC_METTL3_EV_vs_WT_F06.20853.20853.4 5.01E-08 17/78 R.HAWLYQAEEEFEKR.Q "sp|Q96DF8|ESS2_HUMAN,tr|F8WEF8|F8WEF8_HUMAN" 2 1834.8638 1.46 88378 20853 4 1834.863181 459.7232 Splicing factor ESS-2 homolog OS=Homo sapiens OX=9606 GN=ESS2 PE=1 SV=1 4.91 3260.2 - 488376 - - - -0.3635 - 2.782 0.518 - 241.6 1 2 0 -0.0007 14 0 0 0 1.75E+07 1.20E+07 - - - 4.1069 1 221125_WJC_METTL3_EV_vs_WT_F06.20854.20854.2 2.75E-13 21/36 R.K[136.11]DGLVSLLTTSEGADEPQR[166.11].L "sp|P51570|GALK1_HUMAN,tr|K7ERJ9|K7ERJ9_HUMAN,tr|K7ERN9|K7ERN9_HUMAN,tr|K7EII7|K7EII7_HUMAN" 4 2033.0396 2.08 88379 20854 2 2033.03511 1017.5271 Galactokinase OS=Homo sapiens OX=9606 GN=GALK1 PE=1 SV=1 4.32 3260.3 - 413007 - - - -2.2006 - 4.217 0.72 - 1104.7 1 2 0 -0.0045 19 0 0 0 1.64E+07 7.89E+06 - - - 7.8957 0.9999 221125_WJC_METTL3_EV_vs_WT_F06.20855.20855.3 0.00708 14/100 R.EPPPAYEPPAPAPLPPPSAPSLQPSR.K sp|O14828|SCAM3_HUMAN 1 2659.3646 3.98 88380 20855 3 2659.365863 887.4621 Secretory carrier-associated membrane protein 3 OS=Homo sapiens OX=9606 GN=SCAMP3 PE=1 SV=3 4.53 3260.5 - 403390 - - - 0.4738 - 2.669 0.378 - 133.1 1 2 0 0.0013 26 0 0 0 8.01E+06 2.01E+06 - - - 5.0125 1 221125_WJC_METTL3_EV_vs_WT_F06.20858.20858.3 9.27E-11 23/84 K.SDQLLSSNENFTNKVNENELLR.Q "sp|Q15643|TRIPB_HUMAN,tr|H0YJ97|H0YJ97_HUMAN" 2 2563.2514 1.16 88381 20858 3 2563.261381 855.4244 Thyroid receptor-interacting protein 11 OS=Homo sapiens OX=9606 GN=TRIP11 PE=1 SV=3 4.41 3260.9 - 3.21E+06 - - - 3.8845 - 3.988 0.689 - 641.5 1 2 1 0.01 22 0 0 0 4.81E+07 4.13E+07 - - - 9.4985 0.9998 221125_WJC_METTL3_EV_vs_WT_F06.20859.20859.3 2.32E-10 24/76 K.HYFQNTQGLIFVVDSNDR[166.11]ER[166.11].L "sp|P18085|ARF4_HUMAN,sp|P84077|ARF1_HUMAN,sp|P61204|ARF3_HUMAN,sp|P84085|ARF5_HUMAN,tr|F5H423|F5H423_HUMAN,tr|C9J1Z8|C9J1Z8_HUMAN,tr|C9JPM4|C9JPM4_HUMAN,tr|C9JAK5|C9JAK5_HUMAN,tr|F5H0C7|F5H0C7_HUMAN" 9 2457.194 1.01 88382 20859 3 2457.193645 820.0719 ADP-ribosylation factor 4 OS=Homo sapiens OX=9606 GN=ARF4 PE=1 SV=3 5.38 3261 - 3.44E+06 - - - -0.149 - 3.587 0.422 - 545.2 1 2 1 -0.0004 20 0 0 0 4.33E+08 4.31E+08 - - - 6.3436 1 221125_WJC_METTL3_EV_vs_WT_F06.20860.20860.4 7.57E-13 27/114 K.HYFQNTQGLIFVVDSNDR[166.11]ER[166.11].L "sp|P18085|ARF4_HUMAN,sp|P84077|ARF1_HUMAN,sp|P61204|ARF3_HUMAN,sp|P84085|ARF5_HUMAN,tr|F5H423|F5H423_HUMAN,tr|C9J1Z8|C9J1Z8_HUMAN,tr|C9JPM4|C9JPM4_HUMAN,tr|C9JAK5|C9JAK5_HUMAN,tr|F5H0C7|F5H0C7_HUMAN" 9 2457.194 1.11 88383 20860 4 2457.192394 615.3058 ADP-ribosylation factor 4 OS=Homo sapiens OX=9606 GN=ARF4 PE=1 SV=3 5.38 3261.1 - 2.62E+06 - - - -0.6581 - 4.393 0.66 - 637.7 1 2 1 -0.0016 20 0 0 0 3.69E+08 3.32E+08 - - - 5.465 0.9994 221125_WJC_METTL3_EV_vs_WT_F06.20861.20861.4 0.018 12/108 R.GLLQDDAHPTLVTYADHSK[136.11].L "sp|Q86U44|MTA70_HUMAN,tr|F5H6D8|F5H6D8_HUMAN,tr|H0YFV6|H0YFV6_HUMAN,tr|B4DTN4|B4DTN4_HUMAN" 4 2088.0367 0.01 88384 20861 4 2088.035569 523.0165 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 5.13 3261.1 - 1.67E+06 - - - -0.5575 - 2.573 0.317 - 102.6 1 2 0 -0.0012 19 0 0 0 1.80E+05 2.37E+07 - - - 2.3045 1 221125_WJC_METTL3_EV_vs_WT_F06.20864.20864.3 7.06E-14 24/80 K.LK[136.11]ESSHSGVVLSVEEVEAGLK[136.11].G "sp|Q9NRA8|4ET_HUMAN,tr|B1AKL4|B1AKL4_HUMAN,tr|B0QYZ7|B0QYZ7_HUMAN" 3 2212.1922 1.16 88387 20864 3 2212.191558 738.4047 Eukaryotic translation initiation factor 4E transporter OS=Homo sapiens OX=9606 GN=EIF4ENIF1 PE=1 SV=2 4.91 3261.5 - 644418 - - - -0.2803 - 4.657 0.648 - 900.8 1 2 1 -0.0006 21 0 0 0 6.12E+07 5.26E+07 - - - 9.4526 0.9999 221125_WJC_METTL3_EV_vs_WT_F06.20868.20868.4 9.90E-10 20/120 K.LKESSHSGVVLSVEEVEAGLK.G "sp|Q9NRA8|4ET_HUMAN,tr|B1AKL4|B1AKL4_HUMAN,tr|B0QYZ7|B0QYZ7_HUMAN" 3 2196.1638 1.24 88389 20868 4 2196.167364 550.0482 Eukaryotic translation initiation factor 4E transporter OS=Homo sapiens OX=9606 GN=EIF4ENIF1 PE=1 SV=2 4.91 3262 - 3.95E+06 - - - 1.6328 - 4.075 0.558 - 332.5 1 2 1 0.0036 21 0 0 0 1.36E+08 1.10E+08 - - - 4.5463 0.9999 221125_WJC_METTL3_EV_vs_WT_F06.20869.20869.4 4.39E-05 20/120 K.LK[136.11]ESSHSGVVLSVEEVEAGLK[136.11].G "sp|Q9NRA8|4ET_HUMAN,tr|B1AKL4|B1AKL4_HUMAN,tr|B0QYZ7|B0QYZ7_HUMAN" 3 2212.1922 1.24 88390 20869 4 2212.194061 554.0553 Eukaryotic translation initiation factor 4E transporter OS=Homo sapiens OX=9606 GN=EIF4ENIF1 PE=1 SV=2 4.91 3262.1 - 2.82E+06 - - - 0.8512 - 3.756 0.506 - 373.3 1 2 1 0.0019 21 0 0 0 1.35E+08 1.09E+08 - - - 4.0673 1 221125_WJC_METTL3_EV_vs_WT_F06.20872.20872.4 1.38E-08 16/78 R.HAWLYQAEEEFEK[136.11]R[166.11].Q "sp|Q96DF8|ESS2_HUMAN,tr|F8WEF8|F8WEF8_HUMAN" 2 1852.8863 1.45 88393 20872 4 1852.884761 464.2289 Splicing factor ESS-2 homolog OS=Homo sapiens OX=9606 GN=ESS2 PE=1 SV=1 4.91 3262.4 - 762782 - - - -0.8403 - 2.812 0.551 - 208.3 1 2 0 -0.0016 14 0 0 0 1.75E+07 1.21E+07 - - - 4.3978 1 221125_WJC_METTL3_EV_vs_WT_F06.20877.20877.4 8.48E-07 29/114 K.HYFQNTQGLIFVVDSNDRER.L "sp|P18085|ARF4_HUMAN,sp|P84077|ARF1_HUMAN,sp|P61204|ARF3_HUMAN,sp|P84085|ARF5_HUMAN,tr|F5H423|F5H423_HUMAN,tr|C9J1Z8|C9J1Z8_HUMAN,tr|C9JPM4|C9JPM4_HUMAN,tr|C9JAK5|C9JAK5_HUMAN,tr|F5H0C7|F5H0C7_HUMAN" 9 2437.1775 1.11 88396 20877 4 2437.179713 610.3016 ADP-ribosylation factor 4 OS=Homo sapiens OX=9606 GN=ARF4 PE=1 SV=3 5.38 3263.1 - 8.58E+06 - - - 0.9199 - 4.859 0.624 - 738.6 1 2 1 0.0022 20 0 0 0 3.69E+08 3.31E+08 - - - 5.1852 1 221125_WJC_METTL3_EV_vs_WT_F06.20878.20878.3 2.18E-10 27/76 K.HYFQNTQGLIFVVDSNDRER.L "sp|P18085|ARF4_HUMAN,sp|P84077|ARF1_HUMAN,sp|P61204|ARF3_HUMAN,sp|P84085|ARF5_HUMAN,tr|F5H423|F5H423_HUMAN,tr|C9J1Z8|C9J1Z8_HUMAN,tr|C9JPM4|C9JPM4_HUMAN,tr|C9JAK5|C9JAK5_HUMAN,tr|F5H0C7|F5H0C7_HUMAN" 9 2437.1775 1.02 88397 20878 3 2437.177519 813.3998 ADP-ribosylation factor 4 OS=Homo sapiens OX=9606 GN=ARF4 PE=1 SV=3 5.38 3263.1 - 7.00E+06 - - - 0.0197 - 4.215 0.607 - 673.9 1 2 1 0 20 0 0 0 4.34E+08 4.27E+08 - - - 8.7976 1 221125_WJC_METTL3_EV_vs_WT_F06.20879.20879.3 2.55E-10 20/52 R.HAWLYQAEEEFEKR.Q "sp|Q96DF8|ESS2_HUMAN,tr|F8WEF8|F8WEF8_HUMAN" 2 1834.8638 1.48 88398 20879 3 1834.867449 612.6286 Splicing factor ESS-2 homolog OS=Homo sapiens OX=9606 GN=ESS2 PE=1 SV=1 4.91 3263.2 - 4.91E+06 - - - 1.9625 - 3.884 0.659 - 710 1 2 0 0.0036 14 0 0 0 9.20E+07 6.21E+07 - - - 9.4921 1 221125_WJC_METTL3_EV_vs_WT_F06.20881.20881.3 0.000176 18/72 R.GLLQDDAHPTLVTYADHSK[136.11].L "sp|Q86U44|MTA70_HUMAN,tr|F5H6D8|F5H6D8_HUMAN,tr|H0YFV6|H0YFV6_HUMAN,tr|B4DTN4|B4DTN4_HUMAN" 4 2088.0367 0.02 88400 20881 3 2088.039757 697.0195 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 5.13 3263.4 - 757714 - - - 1.4483 - 3.27 0.478 - 319.2 1 2 0 0.003 19 0 0 0 3.84E+05 2.05E+07 - - - 6.7792 0.9999 221125_WJC_METTL3_EV_vs_WT_F06.20882.20882.4 2.60E-06 15/90 K.VDLK[136.11]PLLSSLSANK[136.11]EK[136.11].L "sp|Q9NRA8|4ET_HUMAN,tr|B1AKL4|B1AKL4_HUMAN,tr|B0QYZ7|B0QYZ7_HUMAN" 3 1765.0412 1.3 88401 20882 4 1765.041736 442.2676 Eukaryotic translation initiation factor 4E transporter OS=Homo sapiens OX=9606 GN=EIF4ENIF1 PE=1 SV=2 8.47 3263.6 - 516864 - - - 0.3314 - 2.711 0.508 - 122.1 1 2 1 0.0006 16 0 0 0 1.70E+07 1.31E+07 - - - 3.9988 0.9999 221125_WJC_METTL3_EV_vs_WT_F06.20883.20883.3 0.000176 10/112 R.AVTTVTQSTPVPGPSVPPPEELQVSPGPR[166.11].Q "sp|P51610|HCFC1_HUMAN,tr|H7C1C4|H7C1C4_HUMAN" 2 2933.5374 0.17 88402 20883 3 2933.542083 978.8531 Host cell factor 1 OS=Homo sapiens OX=9606 GN=HCFC1 PE=1 SV=2 4.53 3263.7 - 289012 - - - 1.6059 - 2.412 0.477 - 54.1 1 2 0 0.0047 29 0 0 0 6.53E+05 3.76E+06 - - - 5.8824 1 221125_WJC_METTL3_EV_vs_WT_F06.20886.20886.3 4.15E-13 24/80 K.LKESSHSGVVLSVEEVEAGLK.G "sp|Q9NRA8|4ET_HUMAN,tr|B1AKL4|B1AKL4_HUMAN,tr|B0QYZ7|B0QYZ7_HUMAN" 3 2196.1638 1.16 88403 20886 3 2196.16614 733.0619 Eukaryotic translation initiation factor 4E transporter OS=Homo sapiens OX=9606 GN=EIF4ENIF1 PE=1 SV=2 4.91 3264.1 - 4.98E+06 - - - 1.0755 - 4.687 0.681 - 639.9 1 2 1 0.0024 21 0 0 0 6.12E+07 5.25E+07 - - - 9.8354 1 221125_WJC_METTL3_EV_vs_WT_F06.20889.20889.4 9.17E-13 26/120 K.ADR[166.11]DESSPYAAMLAAQDVAQR[166.11].C "sp|P62263|RS14_HUMAN,tr|A0A2R8Y811|A0A2R8Y811_HUMAN,tr|E5RH77|E5RH77_HUMAN" 3 2284.0657 1.51 88406 20889 4 2284.06678 572.0237 40S ribosomal protein S14 OS=Homo sapiens OX=9606 GN=RPS14 PE=1 SV=3 4.23 3264.4 - 1.04E+06 - - - 0.4733 - 4.542 0.651 - 665.5 1 2 1 0.0011 21 0 0 0 3.21E+08 2.12E+08 - - - 5.3924 1 221125_WJC_METTL3_EV_vs_WT_F06.20890.20890.3 1.56E-10 24/88 K.APTIETVVLYTGETPSEQDQGK[136.11]R[166.11].L sp|Q9BYC8|RM32_HUMAN 1 2536.2776 2.17 88407 20890 3 2536.27978 846.4331 "39S ribosomal protein L32, mitochondrial OS=Homo sapiens OX=9606 GN=MRPL32 PE=1 SV=1" 4.41 3264.5 - 1.04E+06 - - - 0.8666 - 4.883 0.661 - 544.1 1 2 0 0.0022 23 0 0 0 3.72E+07 1.72E+07 - - - 9.629 1 221125_WJC_METTL3_EV_vs_WT_F06.20891.20891.4 2.57E-11 27/120 R.ISLVLGGDHSLAIGSISGHAR.V "sp|P05089|ARGI1_HUMAN,tr|A0A5F9ZGN6|A0A5F9ZGN6_HUMAN" 2 2059.1174 76.47 88408 20891 4 2059.119862 515.7866 Arginase-1 OS=Homo sapiens OX=9606 GN=ARG1 PE=1 SV=2 6.92 3264.6 - 997342 - - - 1.1777 - 4.152 0.635 - 576.1 1 2 0 0.0024 21 0 0 0 1.85E+07 2.42E+05 - - - 5.2231 0.9999 221125_WJC_METTL3_EV_vs_WT_F06.20895.20895.4 1.57E-06 17/90 K.VDLKPLLSSLSANKEK.L "sp|Q9NRA8|4ET_HUMAN,tr|B1AKL4|B1AKL4_HUMAN,tr|B0QYZ7|B0QYZ7_HUMAN" 3 1740.9986 1.29 88412 20895 4 1740.998975 436.2569 Eukaryotic translation initiation factor 4E transporter OS=Homo sapiens OX=9606 GN=EIF4ENIF1 PE=1 SV=2 8.47 3265.1 - 558746 - - - 0.2435 - 2.991 0.497 - 161.9 1 2 1 0.0004 16 0 0 0 1.70E+07 1.31E+07 - - - 3.9377 1 221125_WJC_METTL3_EV_vs_WT_F06.20902.20902.4 7.56E-13 24/120 K.ADRDESSPYAAMLAAQDVAQR.C "sp|P62263|RS14_HUMAN,tr|A0A2R8Y811|A0A2R8Y811_HUMAN,tr|E5RH77|E5RH77_HUMAN" 3 2264.0492 1.52 88417 20902 4 2264.048584 567.0196 40S ribosomal protein S14 OS=Homo sapiens OX=9606 GN=RPS14 PE=1 SV=3 4.23 3265.8 - 2.24E+06 - - - -0.254 - 4.389 0.679 - 586.7 1 2 1 -0.0006 21 0 0 0 3.20E+08 2.11E+08 - - - 5.6249 0.9986 221125_WJC_METTL3_EV_vs_WT_F06.20903.20903.3 6.12E-06 16/88 R.SLNNFC[160.03]SQIGDDRPISYC[160.03]HFSPN.S sp|O43172|PRP4_HUMAN 1 2727.1806 7.75 88418 20903 3 2727.182316 910.0675 U4\U6 small nuclear ribonucleoprotein Prp4 OS=Homo sapiens OX=9606 GN=PRPF4 PE=1 SV=2 5.19 3265.9 - 1.61E+06 - - - 0.6351 - 3.632 0.556 - 156.2 1 1 0 0.0017 23 0 0 0 1.85E+07 2.39E+06 - - - 7.7641 1 221125_WJC_METTL3_EV_vs_WT_F06.20906.20906.2 8.32E-11 22/40 K.ADRDESSPYAAMLAAQDVAQR.C "sp|P62263|RS14_HUMAN,tr|A0A2R8Y811|A0A2R8Y811_HUMAN,tr|E5RH77|E5RH77_HUMAN" 3 2264.0492 1.52 88421 20906 2 2264.054216 1133.0319 40S ribosomal protein S14 OS=Homo sapiens OX=9606 GN=RPS14 PE=1 SV=3 4.23 3266.3 - 647243 - - - 2.2336 - 3.686 0.687 - 311.4 1 2 1 0.0051 21 0 0 0 1.26E+08 8.29E+07 - - - 7.3209 0.9998 221125_WJC_METTL3_EV_vs_WT_F06.20910.20910.4 5.16E-07 23/156 R.LAGQWVEQEVEDRPEVKDENAGVLEVK.Q sp|Q9NWK9|BCD1_HUMAN 1 3065.5306 1.16 88423 20910 4 3065.530474 767.3899 Box C\D snoRNA protein 1 OS=Homo sapiens OX=9606 GN=ZNHIT6 PE=1 SV=1 4.17 3266.9 - 1.57E+06 - - - -0.0277 - 4.429 0.473 - 339.6 1 2 1 -0.0001 27 0 0 0 2.39E+07 2.07E+07 - - - 3.8086 1 221125_WJC_METTL3_EV_vs_WT_F06.20914.20914.4 1.40E-10 27/186 K.VGGTNLGAPGAFGQSPFSQPPAPPHQNTFPPR.S sp|Q96I24|FUBP3_HUMAN 1 3227.5901 2.27 88427 20914 4 3227.59108 807.9048 Far upstream element-binding protein 3 OS=Homo sapiens OX=9606 GN=FUBP3 PE=1 SV=2 9.73 3267.4 - 1.21E+06 - - - 0.3098 - 4.67 0.557 - 241.3 1 2 0 0.001 32 0 0 0 1.89E+08 8.33E+07 - - - 4.5392 0.9999 221125_WJC_METTL3_EV_vs_WT_F06.20915.20915.4 1.95E-09 21/108 K.GFSDKLDFLEGDQKPLAQR.K "sp|Q99848|EBP2_HUMAN,tr|H7C2Q8|H7C2Q8_HUMAN" 2 2163.096 1.05 88428 20915 4 2163.097985 541.7813 Probable rRNA-processing protein EBP2 OS=Homo sapiens OX=9606 GN=EBNA1BP2 PE=1 SV=2 4.68 3267.5 - 871348 - - - 0.9024 - 3.281 0.595 - 249.8 1 2 1 0.002 19 0 0 0 7.73E+06 7.33E+06 - - - 4.8063 1 221125_WJC_METTL3_EV_vs_WT_F06.20916.20916.3 4.81E-06 19/124 K.VGGTNLGAPGAFGQSPFSQPPAPPHQNTFPPR.S sp|Q96I24|FUBP3_HUMAN 1 3227.5901 2.31 88429 20916 3 3227.594572 1076.8706 Far upstream element-binding protein 3 OS=Homo sapiens OX=9606 GN=FUBP3 PE=1 SV=2 9.73 3267.6 - 748324 - - - 1.3918 - 3.743 0.576 - 167.1 1 2 0 0.0045 32 0 0 0 1.52E+08 6.60E+07 - - - 7.9972 1 221125_WJC_METTL3_EV_vs_WT_F06.20917.20917.2 1.54E-11 23/40 K.ADR[166.11]DESSPYAAMLAAQDVAQR[166.11].C "sp|P62263|RS14_HUMAN,tr|A0A2R8Y811|A0A2R8Y811_HUMAN,tr|E5RH77|E5RH77_HUMAN" 3 2284.0657 1.52 88430 20917 2 2284.063201 1143.0401 40S ribosomal protein S14 OS=Homo sapiens OX=9606 GN=RPS14 PE=1 SV=3 4.23 3267.8 - 706851 - - - -1.0937 - 3.725 0.664 - 347.6 1 2 1 -0.0025 21 0 0 0 1.26E+08 8.29E+07 - - - 7.1777 1 221125_WJC_METTL3_EV_vs_WT_F06.20920.20920.4 1.01E-09 30/126 R.VSAVDQVSQTISLTRPFHNGVK.C "sp|Q96F86|EDC3_HUMAN,tr|H3BTH0|H3BTH0_HUMAN,tr|H3BPW9|H3BPW9_HUMAN,tr|H3BMB8|H3BMB8_HUMAN,tr|H3BTF8|H3BTF8_HUMAN,tr|H3BQ37|H3BQ37_HUMAN,tr|H3BQP5|H3BQP5_HUMAN,tr|H3BU87|H3BU87_HUMAN,tr|H3BNJ7|H3BNJ7_HUMAN" 9 2382.2656 1.2 88431 20920 4 2382.268553 596.5737 Enhancer of mRNA-decapping protein 3 OS=Homo sapiens OX=9606 GN=EDC3 PE=1 SV=1 8.73 3268.1 - 4.16E+06 - - - 1.2572 - 5.402 0.561 - 663.9 1 2 0 0.003 22 0 0 0 5.17E+07 4.32E+07 - - - 4.66 1 221125_WJC_METTL3_EV_vs_WT_F06.20928.20928.3 1.43E-08 17/76 K.ETHFDTQNNISTMSAEWVSK.A "sp|Q9H2U1|DHX36_HUMAN,tr|E7EWK3|E7EWK3_HUMAN,tr|H7C5F5|H7C5F5_HUMAN" 3 2324.0379 0.27 88437 20928 3 2324.033146 775.6866 ATP-dependent DNA\RNA helicase DHX36 OS=Homo sapiens OX=9606 GN=DHX36 PE=1 SV=2 4.65 3269.1 - 1.28E+06 - - - -2.0568 - 3.649 0.583 - 373.8 1 2 0 -0.0048 20 0 0 0 1.55E+07 5.66E+07 - - - 8.1789 1 221125_WJC_METTL3_EV_vs_WT_F06.20933.20933.4 9.60E-13 29/144 K.ENPSATLEDLEKPGVDEEPQHVLLR.Y sp|Q92900|RENT1_HUMAN 1 2814.4036 1.3 88440 20933 4 2814.408225 704.6082 Regulator of nonsense transcripts 1 OS=Homo sapiens OX=9606 GN=UPF1 PE=1 SV=2 4.25 3269.8 - 2.20E+06 - - - 1.6547 - 4.689 0.647 - 535.8 1 2 0 0.0047 25 0 0 0 2.35E+08 1.80E+08 - - - 5.3478 0.9965 221125_WJC_METTL3_EV_vs_WT_F06.20934.20934.3 0.00152 17/84 R.VSAVDQVSQTISLTRPFHNGVK.C "sp|Q96F86|EDC3_HUMAN,tr|H3BTH0|H3BTH0_HUMAN,tr|H3BPW9|H3BPW9_HUMAN,tr|H3BMB8|H3BMB8_HUMAN,tr|H3BTF8|H3BTF8_HUMAN,tr|H3BQ37|H3BQ37_HUMAN,tr|H3BQP5|H3BQP5_HUMAN,tr|H3BU87|H3BU87_HUMAN,tr|H3BNJ7|H3BNJ7_HUMAN" 9 2382.2656 1.45 88441 20934 3 2382.251826 795.0958 Enhancer of mRNA-decapping protein 3 OS=Homo sapiens OX=9606 GN=EDC3 PE=1 SV=1 8.73 3269.9 - 690646 - - - -5.7643 - 2.878 0.352 - 235.2 1 2 0 -0.0137 22 0 0 0 6.79E+06 4.69E+06 - - - 4.9668 1 221125_WJC_METTL3_EV_vs_WT_F06.20936.20936.4 1.48E-10 35/144 K.ENPSATLEDLEK[136.11]PGVDEEPQHVLLR[166.11].Y sp|Q92900|RENT1_HUMAN 1 2832.426 1.3 88443 20936 4 2832.42867 709.1138 Regulator of nonsense transcripts 1 OS=Homo sapiens OX=9606 GN=UPF1 PE=1 SV=2 4.25 3270.1 - 1.85E+06 - - - 0.9292 - 4.728 0.61 - 892.1 1 2 0 0.0026 25 0 0 0 2.35E+08 1.80E+08 - - - 5.0289 0.9999 221125_WJC_METTL3_EV_vs_WT_F06.20937.20937.4 1.75E-08 36/186 K.VGGTNLGAPGAFGQSPFSQPPAPPHQNTFPPR[166.11].S sp|Q96I24|FUBP3_HUMAN 1 3237.5984 2.28 88444 20937 4 3237.585719 810.4069 Far upstream element-binding protein 3 OS=Homo sapiens OX=9606 GN=FUBP3 PE=1 SV=2 9.73 3270.3 - 1.53E+06 - - - -3.9013 - 4.849 0.573 - 487.1 1 2 0 -0.0126 32 0 0 0 1.88E+08 8.26E+07 - - - 4.6866 1 221125_WJC_METTL3_EV_vs_WT_F06.20939.20939.3 9.53E-10 19/92 R.GDSEEASGAEEEVGTVAAAATAGK.E "sp|Q9Y467|SALL2_HUMAN,tr|F5H433|F5H433_HUMAN,tr|E7EW59|E7EW59_HUMAN,tr|H0YFS7|H0YFS7_HUMAN" 4 2205.9873 2.62 88446 20939 3 2205.990435 736.3364 Sal-like protein 2 OS=Homo sapiens OX=9606 GN=SALL2 PE=1 SV=4 3.83 3270.5 - 1.05E+06 - - - 1.4075 - 3.241 0.613 - 336.2 1 2 0 0.0031 24 0 0 0 2.04E+07 7.78E+06 - - - 8.1046 1 221125_WJC_METTL3_EV_vs_WT_F06.20944.20944.3 3.53E-07 30/124 K.VGGTNLGAPGAFGQSPFSQPPAPPHQNTFPPR[166.11].S sp|Q96I24|FUBP3_HUMAN 1 3237.5984 2.32 88449 20944 3 3237.58989 1080.2067 Far upstream element-binding protein 3 OS=Homo sapiens OX=9606 GN=FUBP3 PE=1 SV=2 9.73 3271.2 - 1.55E+06 - - - -2.613 - 4.182 0.627 - 633.7 1 2 0 -0.0085 32 0 0 0 1.41E+08 6.08E+07 - - - 8.8198 1 221125_WJC_METTL3_EV_vs_WT_F06.20946.20946.4 1.82E-12 33/156 K.EASPLPAESASAGATLRPLLLSGHGAR.E "sp|P35548|MSX2_HUMAN,tr|D6RIS4|D6RIS4_HUMAN" 2 2628.3984 2.34 88451 20946 4 2628.399326 658.1069 Homeobox protein MSX-2 OS=Homo sapiens OX=9606 GN=MSX2 PE=1 SV=3 6.86 3271.3 - 9.64E+06 - - - 0.3664 - 4.877 0.711 - 786.9 1 2 0 0.001 27 0 0 0 2.12E+08 9.04E+07 - - - 5.9101 1 221125_WJC_METTL3_EV_vs_WT_F06.20950.20950.3 2.10E-17 34/100 R.VGAGDTSDWPTVLSESSTTVAGKPEK.G sp|Q9BUA3|SPNDC_HUMAN 1 2618.2712 5.18 88453 20950 3 2618.271952 873.7643 Spindlin interactor and repressor of chromatin-binding protein OS=Homo sapiens OX=9606 GN=SPINDOC PE=1 SV=3 4.32 3271.8 - 1.73E+06 - - - 0.304 - 5.232 0.772 - 1408.5 1 2 0 0.0008 26 0 0 0 1.95E+08 3.77E+07 - - - 10.9539 1 221125_WJC_METTL3_EV_vs_WT_F06.20954.20954.3 3.56E-11 22/80 K.ADRDESSPYAAMLAAQDVAQR[166.11].C "sp|P62263|RS14_HUMAN,tr|A0A2R8Y811|A0A2R8Y811_HUMAN,tr|E5RH77|E5RH77_HUMAN" 3 2274.0574 - 88456 20954 3 2274.054713 759.0264 40S ribosomal protein S14 OS=Homo sapiens OX=9606 GN=RPS14 PE=1 SV=3 4.23 3272.2 - 3.59E+06 - - - -1.1943 - 4.183 0.611 - 669.4 1 2 1 -0.0027 21 0 0 0 - - - - - 8.7821 1 221125_WJC_METTL3_EV_vs_WT_F06.20961.20961.3 7.45E-12 23/92 K.KAFSAVDTDGNGTINAQELGAALK.A sp|Q9NZT1|CALL5_HUMAN 1 2390.2078 782.59 88460 20961 3 2390.210896 797.7432 Calmodulin-like protein 5 OS=Homo sapiens OX=9606 GN=CALML5 PE=1 SV=2 4.56 3273 - 2.40E+06 - - - 1.3087 - 4.476 0.61 - 362.2 1 2 0 0.0031 24 0 0 0 2.77E+08 3.55E+05 - - - 8.821 0.9999 221125_WJC_METTL3_EV_vs_WT_F06.20965.20965.4 0.00017 26/138 R.LPSEGPRPAHVVVGDVLQAADVDK.T "sp|P30043|BLVRB_HUMAN,tr|A0A2R8YEP4|A0A2R8YEP4_HUMAN,tr|A0A2R8Y7Y9|A0A2R8Y7Y9_HUMAN,tr|M0R192|M0R192_HUMAN,tr|M0QZL1|M0QZL1_HUMAN" 5 2468.3023 0.91 88462 20965 4 2468.302202 618.0829 Flavin reductase (NADPH) OS=Homo sapiens OX=9606 GN=BLVRB PE=1 SV=3 4.66 3273.5 - 1.52E+06 - - - -0.0547 - 4.408 0.447 - 410.1 1 2 0 -0.0001 24 0 0 0 4.96E+07 5.43E+07 - - - 3.5928 1 221125_WJC_METTL3_EV_vs_WT_F06.20968.20968.3 1.09E-08 22/92 R.LPSEGPR[166.11]PAHVVVGDVLQAADVDK[136.11].T "sp|P30043|BLVRB_HUMAN,tr|A0A2R8YEP4|A0A2R8YEP4_HUMAN,tr|A0A2R8Y7Y9|A0A2R8Y7Y9_HUMAN,tr|M0R192|M0R192_HUMAN,tr|M0QZL1|M0QZL1_HUMAN" 5 2486.3248 1.68 88464 20968 3 2486.322087 829.7822 Flavin reductase (NADPH) OS=Homo sapiens OX=9606 GN=BLVRB PE=1 SV=3 4.66 3273.9 - 779902 - - - -1.094 - 4.253 0.436 - 386.8 1 2 0 -0.0027 24 0 0 0 4.22E+07 2.51E+07 - - - 6.7625 1 221125_WJC_METTL3_EV_vs_WT_F06.20973.20973.4 4.77E-16 29/186 K.IQALPTVPVTEEHVGSGLEC[160.03]PVC[160.03]KDDYALGER.V "sp|Q9BV68|RN126_HUMAN,tr|K7EIY6|K7EIY6_HUMAN" 2 3538.7072 1.9 88466 20973 4 3538.702201 885.6841 E3 ubiquitin-protein ligase RNF126 OS=Homo sapiens OX=9606 GN=RNF126 PE=1 SV=2 4.35 3274.5 - 1.40E+06 - - - -1.4183 - 5.094 0.753 - 281.1 1 2 1 -0.005 32 0 0 0 1.68E+08 8.84E+07 - - - 6.2703 0.9979 221125_WJC_METTL3_EV_vs_WT_F06.20975.20975.3 0.00866 16/88 K.K[136.11]QQAIELTQEEPYSDIIATPGPR[166.11].F "sp|O60216|RAD21_HUMAN,tr|E5RI01|E5RI01_HUMAN,tr|E5RG18|E5RG18_HUMAN,tr|E5RFZ5|E5RFZ5_HUMAN" 4 2601.3405 0.64 88468 20975 3 2601.335548 868.1208 Double-strand-break repair protein rad21 homolog OS=Homo sapiens OX=9606 GN=RAD21 PE=1 SV=2 4.41 3274.7 - 762662 - - - -1.9102 - 1.588 0.318 - 32.7 1 2 0 -0.005 23 0 0 0 1.02E+07 1.59E+07 - - - 3.1689 0.9999 221125_WJC_METTL3_EV_vs_WT_F06.20980.20980.3 5.32E-07 16/60 K.SDDILEEGEKNLGNIK.V sp|Q7Z2T5|TRM1L_HUMAN 1 1772.8792 0.73 88470 20980 3 1772.88171 591.967 TRMT1-like protein OS=Homo sapiens OX=9606 GN=TRMT1L PE=1 SV=2 4.18 3275.5 - 933337 - - - 1.4028 - 3.411 0.568 - 315.1 1 2 1 0.0025 16 0 0 0 2.58E+07 3.56E+07 - - - 8.0203 1 221125_WJC_METTL3_EV_vs_WT_F06.20982.20982.4 1.01E-10 26/186 K.IQALPTVPVTEEHVGSGLEC[160.03]PVC[160.03]K[136.11]DDYALGER[166.11].V "sp|Q9BV68|RN126_HUMAN,tr|K7EIY6|K7EIY6_HUMAN" 2 3556.7297 1.9 88472 20982 4 3556.725498 890.1897 E3 ubiquitin-protein ligase RNF126 OS=Homo sapiens OX=9606 GN=RNF126 PE=1 SV=2 4.35 3275.7 - 1.33E+06 - - - -1.1786 - 3.825 0.632 - 246.9 1 2 1 -0.0042 32 0 0 0 1.68E+08 8.84E+07 - - - 5.1308 0.9921 221125_WJC_METTL3_EV_vs_WT_F06.20983.20983.4 0.00245 20/138 R.LPSEGPR[166.11]PAHVVVGDVLQAADVDK[136.11].T "sp|P30043|BLVRB_HUMAN,tr|A0A2R8YEP4|A0A2R8YEP4_HUMAN,tr|A0A2R8Y7Y9|A0A2R8Y7Y9_HUMAN,tr|M0R192|M0R192_HUMAN,tr|M0QZL1|M0QZL1_HUMAN" 5 2486.3248 0.88 88473 20983 4 2487.322477 622.5885 Flavin reductase (NADPH) OS=Homo sapiens OX=9606 GN=BLVRB PE=1 SV=3 4.66 3275.8 - 1.30E+06 - - - 401.2629 - 3.707 0.418 - 256.8 1 2 0 0.9977 24 0 0 0 4.94E+07 5.60E+07 - - - 3.0085 1 221125_WJC_METTL3_EV_vs_WT_F06.20995.20995.3 5.57E-07 13/56 K.QC[160.03]ASLQAAIADAEQR.G sp|P48668|K2C6C_HUMAN 1 1630.7733 48.08 88482 20995 3 1630.772636 544.5984 "Keratin, type II cytoskeletal 6C OS=Homo sapiens OX=9606 GN=KRT6C PE=1 SV=3" 4.37 3277.4 - 302070 - - - -0.4188 - 2.459 0.556 - 139.9 1 2 0 -0.0007 15 0 0 0 4.29E+06 8.92E+04 - - - 7.0865 0.9898 221125_WJC_METTL3_EV_vs_WT_F06.21000.21000.4 0.00772 13/102 R.YK[136.11]VEGFPTIYFAPSGDK[136.11]K[136.11].N "sp|P13667|PDIA4_HUMAN,tr|A0A499FI48|A0A499FI48_HUMAN" 2 2070.0888 0.67 88485 21000 4 2070.093367 518.5295 Protein disulfide-isomerase A4 OS=Homo sapiens OX=9606 GN=PDIA4 PE=1 SV=2 8.38 3278 - 309678 - - - 2.1922 - 2.047 0.279 - 65.2 1 2 1 0.0045 18 0 0 0 6.87E+06 1.03E+07 - - - 1.8986 1 221125_WJC_METTL3_EV_vs_WT_F06.21007.21007.3 5.27E-14 26/96 K.ENPSATLEDLEKPGVDEEPQHVLLR.Y sp|Q92900|RENT1_HUMAN 1 2814.4036 1.05 88490 21007 3 2814.401026 939.1418 Regulator of nonsense transcripts 1 OS=Homo sapiens OX=9606 GN=UPF1 PE=1 SV=2 4.25 3278.8 - 766910 - - - -0.9032 - 4.718 0.718 - 595.1 1 2 0 -0.0025 25 0 0 0 2.71E+07 2.58E+07 - - - 10.1135 0.8831 221125_WJC_METTL3_EV_vs_WT_F06.21008.21008.3 0.0209 Oct-84 K.APSEEDSLSSVPISPYK[136.11]DEPWK[136.11].Y "sp|Q9Y676|RT18B_HUMAN,tr|A0A0G2JIC6|A0A0G2JIC6_HUMAN" 2 2476.1981 0.28 88491 21008 3 2476.213188 826.4066 "28S ribosomal protein S18b, mitochondrial OS=Homo sapiens OX=9606 GN=MRPS18B PE=1 SV=1" 4.18 3278.9 - 531643 - - - 6.113 - 2.016 0.292 - 76.3 1 2 1 0.0151 22 0 0 0 7.68E+06 2.75E+07 - - - 3.4535 1 221125_WJC_METTL3_EV_vs_WT_F06.21013.21013.4 2.98E-08 19/126 K.QAVDFLSNEGHIYSTVDDDHFK.S "sp|P15927|RFA2_HUMAN,tr|Q5TEJ0|Q5TEJ0_HUMAN" 2 2536.1506 1.26 88494 21013 4 2536.155367 635.0449 Replication protein A 32 kDa subunit OS=Homo sapiens OX=9606 GN=RPA2 PE=1 SV=1 4.34 3279.6 - 1.21E+06 - - - 1.8611 - 3.451 0.525 - 192.7 1 2 0 0.0047 22 0 0 0 6.77E+08 5.36E+08 - - - 4.1996 1 221125_WJC_METTL3_EV_vs_WT_F06.21014.21014.4 6.94E-09 22/126 K.QAVDFLSNEGHIYSTVDDDHFK[136.11].S "sp|P15927|RFA2_HUMAN,tr|Q5TEJ0|Q5TEJ0_HUMAN" 2 2544.1648 1.26 88495 21014 4 2544.166529 637.0485 Replication protein A 32 kDa subunit OS=Homo sapiens OX=9606 GN=RPA2 PE=1 SV=1 4.34 3279.7 - 1.54E+06 - - - 0.6611 - 3.612 0.539 - 336 1 2 0 0.0017 22 0 0 0 6.77E+08 5.36E+08 - - - 4.3372 0.9997 221125_WJC_METTL3_EV_vs_WT_F06.21015.21015.4 9.29E-07 16/120 K.KGQLNADEISLRPAQSFLMNK.N "sp|P78344|IF4G2_HUMAN,tr|D3DQV9|D3DQV9_HUMAN" 2 2359.2318 1.41 88496 21015 4 2359.236123 590.8152 Eukaryotic translation initiation factor 4 gamma 2 OS=Homo sapiens OX=9606 GN=EIF4G2 PE=1 SV=1 8.59 3279.9 - 929051 - - - 1.826 - 3.091 0.37 - 172.4 1 2 0 0.0043 21 0 0 0 2.80E+07 1.99E+07 - - - 2.8184 0.9999 221125_WJC_METTL3_EV_vs_WT_F06.21017.21017.3 1.89E-06 16/76 K.QK[136.11]GADFLVTEVENGGSLGSK[136.11].K "sp|P14618|KPYM_HUMAN,tr|H3BQ34|H3BQ34_HUMAN,tr|B4DNK4|B4DNK4_HUMAN,tr|A0A804F6T5|A0A804F6T5_HUMAN,tr|H3BTN5|H3BTN5_HUMAN,tr|A0A804F729|A0A804F729_HUMAN" 6 2051.0506 0.89 88498 21017 3 2051.053345 684.6908 Pyruvate kinase PKM OS=Homo sapiens OX=9606 GN=PKM PE=1 SV=4 4.68 3280.1 - 400113 - - - 1.3388 - 3.129 0.498 - 343 1 2 1 0.0027 20 0 0 0 3.75E+07 4.20E+07 - - - 6.8588 1 221125_WJC_METTL3_EV_vs_WT_F06.21020.21020.3 2.28E-16 28/96 K.ENPSATLEDLEK[136.11]PGVDEEPQHVLLR[166.11].Y sp|Q92900|RENT1_HUMAN 1 2832.426 1.05 88499 21020 3 2832.425377 945.1493 Regulator of nonsense transcripts 1 OS=Homo sapiens OX=9606 GN=UPF1 PE=1 SV=2 4.25 3280.5 - 758420 - - - -0.2334 - 5.289 0.717 - 719 1 2 0 -0.0007 25 0 0 0 2.71E+07 2.58E+07 - - - 10.3657 0.9999 221125_WJC_METTL3_EV_vs_WT_F06.21021.21021.4 8.01E-09 20/120 R.KFGVVLDEIKPSSAPELQAVR.M "sp|O14579|COPE_HUMAN,tr|M0QXB4|M0QXB4_HUMAN,tr|M0R061|M0R061_HUMAN" 3 2282.2634 0.92 88500 21021 4 2282.266696 571.5731 Coatomer subunit epsilon OS=Homo sapiens OX=9606 GN=COPE PE=1 SV=3 6.18 3280.7 - 784023 - - - 1.4297 - 3.631 0.395 - 262.8 1 2 0 0.0033 21 0 0 0 1.28E+07 1.38E+07 - - - 3.0895 1 221125_WJC_METTL3_EV_vs_WT_F06.21023.21023.4 7.06E-05 22/138 K.KVTSVVFHPSQDLVFSASPDATIR.L sp|Q9UMS4|PRP19_HUMAN 1 2600.3599 1.31 88502 21023 4 2600.363976 651.0972 Pre-mRNA-processing factor 19 OS=Homo sapiens OX=9606 GN=PRPF19 PE=1 SV=1 6.75 3280.9 - 1.43E+06 - - - 1.5859 - 3.596 0.503 - 364.5 1 2 0 0.0041 24 0 0 0 3.88E+08 2.97E+08 - - - 4.0137 1 221125_WJC_METTL3_EV_vs_WT_F06.21026.21026.3 5.70E-09 16/88 K.EIETYHNLLEGGQEDFESSGAGK.L "sp|P35527|K1C9_HUMAN,tr|K7EQQ3|K7EQQ3_HUMAN" 2 2509.1245 34 88503 21026 3 2509.122482 837.3821 "Keratin, type I cytoskeletal 9 OS=Homo sapiens OX=9606 GN=KRT9 PE=1 SV=3" 4.14 3281.3 - 509967 - - - -0.8011 - 3.466 0.613 - 285.3 1 2 0 -0.002 23 0 0 0 1.17E+07 3.43E+05 - - - 8.2898 0.9922 221125_WJC_METTL3_EV_vs_WT_F06.21027.21027.3 0.0489 Aug-56 R.GHLESSLLSHLVDPK.D "sp|O94766|B3GA3_HUMAN,tr|G3V150|G3V150_HUMAN" 2 1630.8679 1.24 88504 21027 3 1630.870125 544.6299 Galactosylgalactosylxylosylprotein 3-beta-glucuronosyltransferase 3 OS=Homo sapiens OX=9606 GN=B3GAT3 PE=1 SV=2 5.99 3281.4 - 280541 - - - 1.3821 - 1.646 0.206 - 68.9 1 2 0 0.0023 15 0 0 0 2.35E+07 1.90E+07 - - - 2.1364 0.9997 221125_WJC_METTL3_EV_vs_WT_F06.21028.21028.2 0.0083 14-Oct R.VDEIIWVK[136.11].T sp|Q86U44|MTA70_HUMAN 1 1008.5735 0.02 88505 21028 2 1008.574766 505.294 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 4.37 3281.5 - 3.52E+06 - - - 1.2225 - 2.187 0.351 - 370.6 1 2 0 0.0012 8 0 0 0 5.15E+06 2.53E+08 - - - 3.9932 0.9988 221125_WJC_METTL3_EV_vs_WT_F06.21034.21034.3 1.95E-07 20/68 L.DGR[166.11]PMNIQLVTSQIDAQR[166.11].R "sp|Q86V81|THOC4_HUMAN,tr|E9PB61|E9PB61_HUMAN" 2 2061.054 0.95 88509 21034 3 2061.05644 688.0253 THO complex subunit 4 OS=Homo sapiens OX=9606 GN=ALYREF PE=1 SV=3 5.96 3282.3 - 689164 - - - 1.178 - 3.955 0.578 - 616.8 1 1 0 0.0024 18 0 0 0 1.87E+07 1.96E+07 - - - 8.4073 1 221125_WJC_METTL3_EV_vs_WT_F06.21036.21036.4 1.44E-09 27/138 K.K[136.11]VTSVVFHPSQDLVFSASPDATIR[166.11].L sp|Q9UMS4|PRP19_HUMAN 1 2618.3823 1.31 88511 21036 4 2618.386309 655.6029 Pre-mRNA-processing factor 19 OS=Homo sapiens OX=9606 GN=PRPF19 PE=1 SV=1 6.75 3282.4 - 2.98E+06 - - - 1.5227 - 4.541 0.537 - 484.7 1 2 0 0.004 24 0 0 0 3.88E+08 2.97E+08 - - - 4.3846 0.9993 221125_WJC_METTL3_EV_vs_WT_F06.21037.21037.4 0.000335 13/96 K.EHYVDLKDRPFFAGLVK.Y "sp|P15531|NDKA_HUMAN,tr|Q32Q12|Q32Q12_HUMAN,tr|J3KPD9|J3KPD9_HUMAN,tr|E5RHP0|E5RHP0_HUMAN,tr|E7ERL0|E7ERL0_HUMAN" 5 2033.0734 1.45 88512 21037 4 2033.075881 509.2756 Nucleoside diphosphate kinase A OS=Homo sapiens OX=9606 GN=NME1 PE=1 SV=1 6.85 3282.6 - 592206 - - - 1.1972 - 2.154 0.39 - 106.7 1 2 1 0.0024 17 0 0 0 2.23E+07 1.54E+07 - - - 2.8863 0.9999 221125_WJC_METTL3_EV_vs_WT_F06.21038.21038.3 3.86E-07 16/88 R.ALQSGQC[160.03]AGAALDVFTEEPPRDR.A "sp|O43175|SERA_HUMAN,tr|A0A286YF78|A0A286YF78_HUMAN,tr|A0A2C9F2M7|A0A2C9F2M7_HUMAN,tr|A0A286YF22|A0A286YF22_HUMAN,tr|A0A286YFL2|A0A286YFL2_HUMAN,tr|A0A286YFA2|A0A286YFA2_HUMAN" 6 2487.1812 4.3 88513 21038 3 2487.182345 830.0677 D-3-phosphoglycerate dehydrogenase OS=Homo sapiens OX=9606 GN=PHGDH PE=1 SV=4 4.32 3282.7 - 524509 - - - 0.4459 - 3.16 0.488 - 248.3 1 2 1 0.0011 23 0 0 0 4.17E+07 9.69E+06 - - - 6.6796 0.9971 221125_WJC_METTL3_EV_vs_WT_F06.21039.21039.3 1.80E-06 15/88 K.QSHAASAAPQASSPPDYTMAWAE.Y sp|Q96I24|FUBP3_HUMAN 1 2373.0332 - 88514 21039 3 2373.028862 792.0183 Far upstream element-binding protein 3 OS=Homo sapiens OX=9606 GN=FUBP3 PE=1 SV=2 4.71 3282.8 - 467648 - - - -1.8175 - 2.888 0.561 - 118.4 1 1 0 -0.0043 23 0 0 0 - - - - - 7.2814 1 221125_WJC_METTL3_EV_vs_WT_F06.21045.21045.3 4.94E-07 17/84 K.QAVDFLSNEGHIYSTVDDDHFK[136.11].S "sp|P15927|RFA2_HUMAN,tr|Q5TEJ0|Q5TEJ0_HUMAN" 2 2544.1648 0.44 88518 21045 3 2544.164089 849.0622 Replication protein A 32 kDa subunit OS=Homo sapiens OX=9606 GN=RPA2 PE=1 SV=1 4.34 3283.6 - 3.36E+06 - - - -0.2979 - 3.534 0.591 - 333.9 1 2 0 -0.0008 22 0 0 0 5.59E+07 1.26E+08 - - - 8.1219 1 221125_WJC_METTL3_EV_vs_WT_F06.21046.21046.4 1.97E-12 25/126 R.FHVNLLC[160.03]GEEQGSDAALHFNPR.L sp|P47929|LEG7_HUMAN 1 2510.1761 99.99 88519 21046 4 2510.177956 628.5513 Galectin-7 OS=Homo sapiens OX=9606 GN=LGALS7 PE=1 SV=2 5.27 3283.7 - 1.08E+06 - - - 0.743 - 4.334 0.633 - 566.3 1 2 0 0.0019 22 0 0 0 2.07E+08 2.07E+06 - - - 5.215 1 221125_WJC_METTL3_EV_vs_WT_F06.21047.21047.3 1.04E-07 19/84 K.QAVDFLSNEGHIYSTVDDDHFK.S "sp|P15927|RFA2_HUMAN,tr|Q5TEJ0|Q5TEJ0_HUMAN" 2 2536.1506 0.44 88520 21047 3 2536.149912 846.3908 Replication protein A 32 kDa subunit OS=Homo sapiens OX=9606 GN=RPA2 PE=1 SV=1 4.34 3283.8 - 4.10E+06 - - - -0.2898 - 3.533 0.578 - 339.1 1 2 0 -0.0007 22 0 0 0 5.59E+07 1.26E+08 - - - 7.9763 1 221125_WJC_METTL3_EV_vs_WT_F06.21048.21048.3 6.18E-11 19/60 K.HSQAVEELAEQLEQTK.R sp|P35579|MYH9_HUMAN 1 1838.901 1.08 88521 21048 3 1838.902066 613.9743 Myosin-9 OS=Homo sapiens OX=9606 GN=MYH9 PE=1 SV=4 4.48 3283.8 - 1.52E+06 - - - 0.5683 - 3.903 0.574 - 542.4 1 2 0 0.001 16 0 0 0 7.41E+07 6.84E+07 - - - 8.4333 0.9989 221125_WJC_METTL3_EV_vs_WT_F06.21050.21050.3 5.52E-08 24/68 L.DGRPMNIQLVTSQIDAQR.R "sp|Q86V81|THOC4_HUMAN,tr|E9PB61|E9PB61_HUMAN" 2 2041.0375 0.95 88523 21050 3 2041.038648 681.3531 THO complex subunit 4 OS=Homo sapiens OX=9606 GN=ALYREF PE=1 SV=3 5.96 3284.1 - 735607 - - - 0.5762 - 4.581 0.528 - 1008.4 1 1 0 0.0012 18 0 0 0 1.87E+07 1.96E+07 - - - 8.2161 0.9994 221125_WJC_METTL3_EV_vs_WT_F06.21051.21051.3 0.00127 Sep-56 R.GHLESSLLSHLVDPK[136.11].D "sp|O94766|B3GA3_HUMAN,tr|G3V150|G3V150_HUMAN" 2 1638.8821 1.24 88524 21051 3 1638.881746 547.3013 Galactosylgalactosylxylosylprotein 3-beta-glucuronosyltransferase 3 OS=Homo sapiens OX=9606 GN=B3GAT3 PE=1 SV=2 5.99 3284.2 - 588363 - - - -0.1983 - 1.796 0.328 - 82.4 1 2 0 -0.0003 15 0 0 0 2.35E+07 1.90E+07 - - - 3.7247 0.9966 221125_WJC_METTL3_EV_vs_WT_F06.21053.21053.3 2.79E-06 14/68 K.DFDFESANAQFNKEEIDR.E "sp|Q8ND56|LS14A_HUMAN,tr|A0A140TA76|A0A140TA76_HUMAN,tr|K7EMZ9|K7EMZ9_HUMAN" 3 2173.9552 1.08 88526 21053 3 2174.959266 725.659 Protein LSM14 homolog A OS=Homo sapiens OX=9606 GN=LSM14A PE=1 SV=3 4.02 3284.5 - 307188 - - - 461.8421 - 2.694 0.519 - 155.5 1 2 1 1.004 18 0 0 0 3.18E+08 2.95E+08 - - - 6.516 1 221125_WJC_METTL3_EV_vs_WT_F06.21056.21056.3 1.55E-09 22/60 K.HSQAVEELAEQLEQTK[136.11].R sp|P35579|MYH9_HUMAN 1 1846.9152 1.08 88527 21056 3 1846.916246 616.6457 Myosin-9 OS=Homo sapiens OX=9606 GN=MYH9 PE=1 SV=4 4.48 3284.9 - 2.13E+06 - - - 0.555 - 4.12 0.625 - 858.3 1 2 0 0.001 16 0 0 0 7.41E+07 6.84E+07 - - - 9.1407 1 221125_WJC_METTL3_EV_vs_WT_F06.21057.21057.3 3.60E-15 30/116 R.HELLLGAGSGPGAGQQQATPGALLQAGPPR.C sp|Q96DI7|SNR40_HUMAN 1 2848.4944 1.7 88528 21057 3 2848.491997 950.5054 U5 small nuclear ribonucleoprotein 40 kDa protein OS=Homo sapiens OX=9606 GN=SNRNP40 PE=1 SV=1 6.75 3285 - 1.18E+06 - - - -0.8397 - 5.824 0.721 - 518.9 1 2 0 -0.0024 30 0 0 0 8.37E+07 4.93E+07 - - - 10.6315 1 221125_WJC_METTL3_EV_vs_WT_F06.21059.21059.2 2.40E-08 15/30 K.TITLEVEPSDTIENVK[136.11].A "sp|P62979|RS27A_HUMAN,sp|P0CG48|UBC_HUMAN,sp|P0CG47|UBB_HUMAN,sp|P62987|RL40_HUMAN,tr|F5H388|F5H388_HUMAN,tr|F5GYU3|F5GYU3_HUMAN,tr|B4DV12|B4DV12_HUMAN,tr|J3QSA3|J3QSA3_HUMAN,tr|Q5PY61|Q5PY61_HUMAN,tr|F5H2Z3|F5H2Z3_HUMAN,tr|J3QS39|J3QS39_HUMAN,tr|J3QTR3|J3QTR3_HUMAN,tr|Q96C32|Q96C32_HUMAN,tr|M0R1V7|M0R1V7_HUMAN,tr|F5H747|F5H747_HUMAN,tr|F5H747|F5H747_HUMAN,tr|F5GXK7|F5GXK7_HUMAN,tr|F5GXK7|F5GXK7_HUMAN,tr|F5H6Q2|F5H6Q2_HUMAN,tr|F5GZ39|F5GZ39_HUMAN,tr|J3QKN0|J3QKN0_HUMAN,tr|J3QKN0|J3QKN0_HUMAN,tr|J3QKN0|J3QKN0_HUMAN,tr|F5H265|F5H265_HUMAN" 24 1794.9342 0.63 88530 21059 2 1794.936407 898.4744 Ubiquitin-40S ribosomal protein S27a OS=Homo sapiens OX=9606 GN=RPS27A PE=1 SV=2 4 3285.3 - 647615 - - - 1.2156 - 3.076 0.583 - 579.7 1 2 0 0.0022 16 0 0 0 7.87E+06 1.24E+07 - - - 6.1088 0.9024 221125_WJC_METTL3_EV_vs_WT_F06.21061.21061.4 0.195 10/102 R.YKVEGFPTIYFAPSGDKK.N "sp|P13667|PDIA4_HUMAN,tr|A0A499FI48|A0A499FI48_HUMAN" 2 2046.0462 0.68 88532 21061 4 2046.050889 512.5188 Protein disulfide-isomerase A4 OS=Homo sapiens OX=9606 GN=PDIA4 PE=1 SV=2 8.38 3285.5 - 250508 - - - 2.2776 - 1.805 0.186 - 54.8 1 2 1 0.0047 18 0 0 0 6.78E+06 1.00E+07 - - - 1.046 0.9999 221125_WJC_METTL3_EV_vs_WT_F06.21067.21067.3 6.68E-07 16/76 K.QKGADFLVTEVENGGSLGSK.K "sp|P14618|KPYM_HUMAN,tr|H3BQ34|H3BQ34_HUMAN,tr|B4DNK4|B4DNK4_HUMAN,tr|A0A804F6T5|A0A804F6T5_HUMAN,tr|H3BTN5|H3BTN5_HUMAN,tr|A0A804F729|A0A804F729_HUMAN" 6 2035.0222 0.89 88535 21067 3 2035.023417 679.348 Pyruvate kinase PKM OS=Homo sapiens OX=9606 GN=PKM PE=1 SV=4 4.68 3286.3 - 2.07E+06 - - - 0.5985 - 3.263 0.563 - 292.2 1 2 1 0.0012 20 0 0 0 3.75E+07 4.20E+07 - - - 7.6857 0.9999 221125_WJC_METTL3_EV_vs_WT_F06.21069.21069.4 2.97E-07 17/174 R.HELLLGAGSGPGAGQQQATPGALLQAGPPR[166.11].C sp|Q96DI7|SNR40_HUMAN 1 2858.5027 3.25 88537 21069 4 2858.499164 715.6329 U5 small nuclear ribonucleoprotein 40 kDa protein OS=Homo sapiens OX=9606 GN=SNRNP40 PE=1 SV=1 6.75 3286.5 - 361552 - - - -1.2227 - 3.607 0.418 - 155.8 1 2 0 -0.0035 30 0 0 0 2.05E+07 6.31E+06 - - - 3.2559 0.9999 221125_WJC_METTL3_EV_vs_WT_F06.21073.21073.3 1.97E-07 20/60 K.EQIDIFEGIKDSQAQR.M "sp|Q96I99|SUCB2_HUMAN,tr|H0Y852|H0Y852_HUMAN,tr|E9PDQ8|E9PDQ8_HUMAN" 3 1875.9327 1.6 88539 21073 3 1875.933063 626.3182 "Succinate--CoA ligase [GDP-forming] subunit beta, mitochondrial OS=Homo sapiens OX=9606 GN=SUCLG2 PE=1 SV=2" 4.32 3287 - 1.40E+06 - - - 0.217 - 3.718 0.509 - 797.5 1 2 1 0.0004 16 0 0 0 3.10E+07 1.94E+07 - - - 7.5842 1 221125_WJC_METTL3_EV_vs_WT_F06.21075.21075.3 3.44E-14 31/84 R.FHVNLLC[160.03]GEEQGSDAALHFNPR.L sp|P47929|LEG7_HUMAN 1 2510.1761 999 88541 21075 3 2510.184678 837.7326 Galectin-7 OS=Homo sapiens OX=9606 GN=LGALS7 PE=1 SV=2 5.27 3287.1 - 2.07E+06 - - - 3.4209 - 5.173 0.72 - 1138.7 1 2 0 0.0086 22 0 0 0 4.19E+07 0.00E+00 - - - 10.4613 0.9993 221125_WJC_METTL3_EV_vs_WT_F06.21077.21077.2 0.00175 30-Sep K.TITLEVEPSDTIENVK.A "sp|P62979|RS27A_HUMAN,sp|P0CG48|UBC_HUMAN,sp|P0CG47|UBB_HUMAN,sp|P62987|RL40_HUMAN,tr|F5H388|F5H388_HUMAN,tr|F5GYU3|F5GYU3_HUMAN,tr|B4DV12|B4DV12_HUMAN,tr|J3QSA3|J3QSA3_HUMAN,tr|Q5PY61|Q5PY61_HUMAN,tr|F5H2Z3|F5H2Z3_HUMAN,tr|J3QS39|J3QS39_HUMAN,tr|J3QTR3|J3QTR3_HUMAN,tr|Q96C32|Q96C32_HUMAN,tr|M0R1V7|M0R1V7_HUMAN,tr|F5H747|F5H747_HUMAN,tr|F5H747|F5H747_HUMAN,tr|F5GXK7|F5GXK7_HUMAN,tr|F5GXK7|F5GXK7_HUMAN,tr|F5H6Q2|F5H6Q2_HUMAN,tr|F5GZ39|F5GZ39_HUMAN,tr|J3QKN0|J3QKN0_HUMAN,tr|J3QKN0|J3QKN0_HUMAN,tr|J3QKN0|J3QKN0_HUMAN,tr|F5H265|F5H265_HUMAN" 24 1786.92 0.45 88543 21077 2 1786.916316 894.4673 Ubiquitin-40S ribosomal protein S27a OS=Homo sapiens OX=9606 GN=RPS27A PE=1 SV=2 4 3287.4 - 352137 - - - -2.0756 - 2.019 0.38 - 195.8 1 2 0 -0.0037 16 0 0 0 7.87E+06 1.75E+07 - - - 3.5739 1 221125_WJC_METTL3_EV_vs_WT_F06.21080.21080.3 8.85E-13 25/92 K.K[136.11]VTSVVFHPSQDLVFSASPDATIR[166.11].L sp|Q9UMS4|PRP19_HUMAN 1 2618.3823 1.8 88544 21080 3 2618.384718 873.8014 Pre-mRNA-processing factor 19 OS=Homo sapiens OX=9606 GN=PRPF19 PE=1 SV=1 6.75 3287.8 - 7.56E+06 - - - 0.9151 - 5.011 0.674 - 561.8 1 2 0 0.0024 24 0 0 0 1.56E+08 8.65E+07 - - - 9.797 1 221125_WJC_METTL3_EV_vs_WT_F06.21082.21082.4 2.99E-11 34/174 R.HELLLGAGSGPGAGQQQATPGALLQAGPPR.C sp|Q96DI7|SNR40_HUMAN 1 2848.4944 3.25 88546 21082 4 2848.498719 713.1309 U5 small nuclear ribonucleoprotein 40 kDa protein OS=Homo sapiens OX=9606 GN=SNRNP40 PE=1 SV=1 6.75 3288 - 1.69E+06 - - - 1.5201 - 5.459 0.679 - 660.9 1 2 0 0.0043 30 0 0 0 2.05E+07 6.31E+06 - - - 5.6542 0.998 221125_WJC_METTL3_EV_vs_WT_F06.21085.21085.4 0.000644 18/90 K.ELHDLFNLPHDR[166.11]PYFK[136.11].R "sp|Q9NUQ7|UFSP2_HUMAN,tr|D6RGX2|D6RGX2_HUMAN,tr|H0YA18|H0YA18_HUMAN" 3 2058.0442 1.31 88549 21085 4 2058.032013 515.5183 Ufm1-specific protease 2 OS=Homo sapiens OX=9606 GN=UFSP2 PE=1 SV=3 6.01 3288.4 - 914256 - - - -5.9294 - 3.364 0.422 - 291.6 1 2 0 -0.0122 16 0 0 0 5.99E+07 4.57E+07 - - - 3.323 1 221125_WJC_METTL3_EV_vs_WT_F06.21090.21090.3 5.61E-10 23/88 K.TVQTAAANAASTAASSAAQNAFK.G "sp|O15126|SCAM1_HUMAN,tr|A0A087WU14|A0A087WU14_HUMAN,tr|A0A087WXB0|A0A087WXB0_HUMAN" 3 2151.0556 1.21 88552 21090 3 2151.055057 718.0258 Secretory carrier-associated membrane protein 1 OS=Homo sapiens OX=9606 GN=SCAMP1 PE=1 SV=2 8.41 3289 - 875119 - - - -0.2641 - 4.695 0.584 - 566.1 1 2 0 -0.0006 23 0 0 0 5.77E+07 4.78E+07 - - - 8.6789 0.9823 221125_WJC_METTL3_EV_vs_WT_F06.21091.21091.3 1.68E-09 19/108 R.NAVIGLNLYC[160.03]GGAGLGAGSGGATR[166.11]PGGR[166.11].L "sp|Q07820|MCL1_HUMAN,tr|A0A087WT64|A0A087WT64_HUMAN" 2 2592.3094 1.69 88553 21091 3 2592.283995 865.1104 Induced myeloid leukemia cell differentiation protein Mcl-1 OS=Homo sapiens OX=9606 GN=MCL1 PE=1 SV=3 9.5 3289.1 - 527117 - - - -9.7971 - 3.162 0.329 - 262.2 1 2 0 -0.0254 28 0 0 0 3.06E+06 1.80E+06 - - - 4.8495 0.9978 221125_WJC_METTL3_EV_vs_WT_F06.21092.21092.4 0.013 9/120 R.RRPGLGALAAGVPAMAESVER.L tr|A0A804HJ86|A0A804HJ86_HUMAN 1 2107.132 2.77 88554 21092 4 2107.130725 527.7903 Ubiquitin-like modifier-activating enzyme 5 OS=Homo sapiens OX=9606 GN=UBA5 PE=4 SV=1 9.51 3289.2 - 357339 - - - -0.6245 - 2.062 0.287 - 34.6 2 2 0 -0.0013 21 0 0 0 4.27E+06 1.54E+06 - - - 1.7335 1 221125_WJC_METTL3_EV_vs_WT_F06.21096.21096.4 2.00E-05 20/90 K.ELHDLFNLPHDRPYFK.R "sp|Q9NUQ7|UFSP2_HUMAN,tr|D6RGX2|D6RGX2_HUMAN,tr|H0YA18|H0YA18_HUMAN" 3 2040.0217 1.31 88556 21096 4 2040.023095 511.0127 Ufm1-specific protease 2 OS=Homo sapiens OX=9606 GN=UFSP2 PE=1 SV=3 6.01 3289.7 - 1.51E+06 - - - 0.6613 - 3.554 0.467 - 375.8 1 2 0 0.0013 16 0 0 0 5.99E+07 4.57E+07 - - - 3.7371 1 221125_WJC_METTL3_EV_vs_WT_F06.21097.21097.3 3.01E-10 22/88 K.TVQTAAANAASTAASSAAQNAFK[136.11].G "sp|O15126|SCAM1_HUMAN,tr|A0A087WU14|A0A087WU14_HUMAN,tr|A0A087WXB0|A0A087WXB0_HUMAN" 3 2159.0698 1.21 88557 21097 3 2160.066142 720.6972 Secretory carrier-associated membrane protein 1 OS=Homo sapiens OX=9606 GN=SCAMP1 PE=1 SV=2 8.41 3289.9 - 1.58E+06 - - - 461.4566 - 4.752 0.591 - 515.8 1 2 0 0.9963 23 0 0 0 5.77E+07 4.78E+07 - - - 8.5094 1 221125_WJC_METTL3_EV_vs_WT_F06.21098.21098.3 8.44E-11 22/68 K.DFDFESANAQFNK[136.11]EEIDR[166.11].E "sp|Q8ND56|LS14A_HUMAN,tr|A0A140TA76|A0A140TA76_HUMAN,tr|K7EMZ9|K7EMZ9_HUMAN" 3 2191.9777 1.08 88558 21098 3 2191.977072 731.6665 Protein LSM14 homolog A OS=Homo sapiens OX=9606 GN=LSM14A PE=1 SV=3 4.02 3289.9 - 1.19E+07 - - - -0.292 - 3.847 0.705 - 396.8 1 2 1 -0.0006 18 0 0 0 3.18E+08 2.95E+08 - - - 9.7548 0.9999 221125_WJC_METTL3_EV_vs_WT_F06.21105.21105.4 1.81E-07 20/108 R.ALEESNYELEGKIKEWYEK.H "sp|P13645|K1C10_HUMAN,tr|A0A1B0GVI3|A0A1B0GVI3_HUMAN" 2 2357.1427 70.02 88563 21105 4 2357.145178 590.293 "Keratin, type I cytoskeletal 10 OS=Homo sapiens OX=9606 GN=KRT10 PE=1 SV=6" 4.48 3290.8 - 1.12E+06 - - - 1.0479 - 3.68 0.538 - 330.9 1 2 2 0.0025 19 0 0 0 1.45E+07 2.07E+05 - - - 4.3488 1 221125_WJC_METTL3_EV_vs_WT_F06.21106.21106.3 9.75E-19 34/116 R.HELLLGAGSGPGAGQQQATPGALLQAGPPR[166.11].C sp|Q96DI7|SNR40_HUMAN 1 2858.5027 1.64 88564 21106 3 2858.502516 953.8415 U5 small nuclear ribonucleoprotein 40 kDa protein OS=Homo sapiens OX=9606 GN=SNRNP40 PE=1 SV=1 6.75 3290.9 - 2.95E+06 - - - -0.05 - 6.196 0.754 - 788.6 1 2 0 -0.0001 30 0 0 0 8.37E+07 5.11E+07 - - - 11.1425 1 221125_WJC_METTL3_EV_vs_WT_F06.21107.21107.4 1.12E-05 29/132 K.QLDQC[160.03]EMILQASEYEDLEHKPGR.L sp|Q7Z4H3|HDDC2_HUMAN 1 2788.2796 4.03 88565 21107 4 2788.276955 698.0772 5'-deoxynucleotidase HDDC2 OS=Homo sapiens OX=9606 GN=HDDC2 PE=1 SV=1 4.35 3291 - 993550 - - - -0.9594 - 5.173 0.606 - 641.6 1 2 0 -0.0027 23 0 0 0 9.74E+07 2.41E+07 - - - 5.0323 1 221125_WJC_METTL3_EV_vs_WT_F06.21114.21114.3 1.18E-08 22/88 K.TTYDSSLSSYTVPLEKDNSEEFR.Q "sp|Q8WWM7|ATX2L_HUMAN,tr|H3BSK9|H3BSK9_HUMAN,tr|H3BUF6|H3BUF6_HUMAN" 3 2667.2188 1.5 88570 21114 3 2667.214918 890.0802 Ataxin-2-like protein OS=Homo sapiens OX=9606 GN=ATXN2L PE=1 SV=2 4.18 3291.9 - 701353 - - - -1.4502 - 4.367 0.643 - 335.1 1 2 1 -0.0039 23 0 0 0 8.46E+07 5.66E+07 - - - 9.1658 0.9998 221125_WJC_METTL3_EV_vs_WT_F06.21115.21115.3 1.35E-09 21/76 R.EK[136.11]QSDDEVYAPGLDIESSLK[136.11].Q sp|Q15459|SF3A1_HUMAN 1 2238.0874 0.84 88571 21115 3 2238.093992 747.0364 Splicing factor 3A subunit 1 OS=Homo sapiens OX=9606 GN=SF3A1 PE=1 SV=1 4.02 3292.1 - 1.11E+06 - - - 2.9284 - 3.577 0.602 - 540 1 2 1 0.0066 20 0 0 0 2.70E+07 3.21E+07 - - - 8.3419 0.9987 221125_WJC_METTL3_EV_vs_WT_F06.21118.21118.4 0.00284 14/96 K.K[136.11]IGDEYFTFITDC[160.03]K[136.11]DPK[136.11].A "sp|P49368|TCPG_HUMAN,tr|B4DUR8|B4DUR8_HUMAN" 2 2100.03 0.28 88574 21118 4 2100.033368 526.0148 T-complex protein 1 subunit gamma OS=Homo sapiens OX=9606 GN=CCT3 PE=1 SV=4 4.68 3292.4 - 876518 - - - 1.6066 - 1.934 0.371 - 110.4 1 2 1 0.0034 17 0 0 0 1.11E+08 3.95E+08 - - - 2.6833 1 221125_WJC_METTL3_EV_vs_WT_F06.21120.21120.2 2.04E-13 16/34 K.DFDFESANAQFNKEEIDR.E "sp|Q8ND56|LS14A_HUMAN,tr|A0A140TA76|A0A140TA76_HUMAN,tr|K7EMZ9|K7EMZ9_HUMAN" 3 2173.9552 1.25 88576 21120 2 2173.952798 1087.9849 Protein LSM14 homolog A OS=Homo sapiens OX=9606 GN=LSM14A PE=1 SV=3 4.02 3292.7 - 506886 - - - -1.1242 - 3.413 0.708 - 678.2 1 2 1 -0.0024 18 0 0 0 5.53E+06 4.42E+06 - - - 7.2876 0.9886 221125_WJC_METTL3_EV_vs_WT_F06.21121.21121.4 0.000103 13/108 A.FLGNSVLGHLENMHPDNSK.A "sp|Q8IWZ3|ANKH1_HUMAN,tr|A0A0A0MQZ8|A0A0A0MQZ8_HUMAN,tr|H0Y472|H0Y472_HUMAN,tr|H0Y7Y3|H0Y7Y3_HUMAN,tr|H0Y4P6|H0Y4P6_HUMAN,tr|H7C0V5|H7C0V5_HUMAN,tr|H0Y785|H0Y785_HUMAN" 7 2108.0109 0.89 88577 21121 4 2108.015666 528.01 Ankyrin repeat and KH domain-containing protein 1 OS=Homo sapiens OX=9606 GN=ANKHD1 PE=1 SV=1 5.99 3292.8 - 215835 - - - 2.25 - 2.522 0.469 - 96.2 1 1 0 0.0047 19 0 0 0 1.67E+07 1.88E+07 - - - 3.6198 0.9999 221125_WJC_METTL3_EV_vs_WT_F06.21125.21125.4 3.46E-05 12/108 R.GLLQDDAHPTLVTYADHSK[136.11].L "sp|Q86U44|MTA70_HUMAN,tr|F5H6D8|F5H6D8_HUMAN,tr|H0YFV6|H0YFV6_HUMAN,tr|B4DTN4|B4DTN4_HUMAN" 4 2088.0367 0.01 88579 21125 4 2088.036846 523.0165 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 5.13 3293.3 - 1.51E+06 - - - 0.0541 - 2.537 0.452 - 139.3 1 2 0 0.0001 19 0 0 0 3.96E+05 3.10E+07 - - - 3.4751 1 221125_WJC_METTL3_EV_vs_WT_F06.21128.21128.3 5.92E-09 15/96 K.VIVQFQPSSVPDEWGTTQDGQTRPR.V "sp|Q9Y6Y8|S23IP_HUMAN,tr|H7C0V8|H7C0V8_HUMAN" 2 2827.3889 0.94 88582 21128 3 2827.393429 943.4702 SEC23-interacting protein OS=Homo sapiens OX=9606 GN=SEC23IP PE=1 SV=1 4.56 3293.6 - 593975 - - - 1.5948 - 3.034 0.661 - 145.3 1 2 0 0.0045 25 0 0 0 9.94E+06 1.06E+07 - - - 8.4617 0.9994 221125_WJC_METTL3_EV_vs_WT_F06.21130.21130.4 6.89E-07 16/102 R.FAIGSQVSEHSIIKDFTK.Q "sp|P33992|MCM5_HUMAN,tr|B1AHB1|B1AHB1_HUMAN" 2 2006.0473 0.54 88584 21130 4 2006.053134 502.5191 DNA replication licensing factor MCM5 OS=Homo sapiens OX=9606 GN=MCM5 PE=1 SV=5 6.75 3293.9 - 259445 - - - 2.9122 - 2.889 0.471 - 201.8 1 2 1 0.0058 18 0 0 0 6.30E+06 1.16E+07 - - - 3.6874 1 221125_WJC_METTL3_EV_vs_WT_F06.21133.21133.3 1.02E-06 18/64 K.K[136.11]IGDEYFTFITDC[160.03]K[136.11]DPK[136.11].A "sp|P49368|TCPG_HUMAN,tr|B4DUR8|B4DUR8_HUMAN" 2 2100.03 0.27 88585 21133 3 2100.034007 701.0173 T-complex protein 1 subunit gamma OS=Homo sapiens OX=9606 GN=CCT3 PE=1 SV=4 4.68 3294.3 - 3.35E+06 - - - 1.9109 - 3.381 0.616 - 233.9 1 2 1 0.004 17 0 0 0 1.54E+08 5.72E+08 - - - 8.4841 1 221125_WJC_METTL3_EV_vs_WT_F06.21134.21134.3 1.51E-13 25/88 K.TTYDSSLSSYTVPLEK[136.11]DNSEEFR[166.11].Q "sp|Q8WWM7|ATX2L_HUMAN,tr|H3BSK9|H3BSK9_HUMAN,tr|H3BUF6|H3BUF6_HUMAN" 3 2685.2413 1.5 88586 21134 3 2685.240409 896.0877 Ataxin-2-like protein OS=Homo sapiens OX=9606 GN=ATXN2L PE=1 SV=2 4.18 3294.4 - 1.24E+06 - - - -0.3154 - 4.533 0.696 - 442.5 1 2 1 -0.0008 23 0 0 0 8.46E+07 5.66E+07 - - - 9.8451 0.9982 221125_WJC_METTL3_EV_vs_WT_F06.21136.21136.4 0.000128 15/96 K.KIGDEYFTFITDC[160.03]KDPK.A "sp|P49368|TCPG_HUMAN,tr|B4DUR8|B4DUR8_HUMAN" 2 2075.9874 0.28 88588 21136 4 2075.990884 520.0041 T-complex protein 1 subunit gamma OS=Homo sapiens OX=9606 GN=CCT3 PE=1 SV=4 4.68 3294.7 - 793194 - - - 1.6811 - 2.206 0.348 - 118.4 1 2 1 0.0035 17 0 0 0 1.11E+08 3.95E+08 - - - 2.5287 0.9938 221125_WJC_METTL3_EV_vs_WT_F06.21140.21140.4 1.48E-06 18/108 C.K[136.11]ILGSGISSSSVLHGMVFK[136.11].K sp|P50990|TCPQ_HUMAN 1 1962.0943 0.21 88592 21140 4 1962.100041 491.5309 T-complex protein 1 subunit theta OS=Homo sapiens OX=9606 GN=CCT8 PE=1 SV=4 10 3295.2 - 271782 - - - 2.9163 - 2.963 0.572 - 231.7 1 1 0 0.0057 19 0 0 0 8.26E+05 3.97E+06 - - - 4.5705 1 221125_WJC_METTL3_EV_vs_WT_F06.21146.21146.3 1.19E-07 17/68 K.YVHYEIDAC[160.03]MDSEAPGSK[136.11].D "sp|Q86U44|MTA70_HUMAN,tr|H0YFV6|H0YFV6_HUMAN" 2 2078.8805 0.01 88596 21146 3 2078.887211 693.9674 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 4.31 3295.9 - 3.34E+06 - - - 3.232 - 2.863 0.637 - 283.6 1 2 0 0.0067 18 0 0 0 3.94E+06 3.51E+08 - - - 8.2593 0.9741 221125_WJC_METTL3_EV_vs_WT_F06.21148.21148.4 8.61E-05 14/108 A.FLGNSVLGHLENMHPDNSK[136.11].A "sp|Q8IWZ3|ANKH1_HUMAN,tr|A0A0A0MQZ8|A0A0A0MQZ8_HUMAN,tr|H0Y472|H0Y472_HUMAN,tr|H0Y7Y3|H0Y7Y3_HUMAN,tr|H0Y4P6|H0Y4P6_HUMAN,tr|H7C0V5|H7C0V5_HUMAN,tr|H0Y785|H0Y785_HUMAN" 7 2116.0251 1.48 88598 21148 4 2116.028147 530.0136 Ankyrin repeat and KH domain-containing protein 1 OS=Homo sapiens OX=9606 GN=ANKHD1 PE=1 SV=1 5.99 3296.2 - 581567 - - - 1.4291 - 2.814 0.372 - 89.1 1 1 0 0.003 19 0 0 0 1.53E+07 1.03E+07 - - - 2.813 0.9992 221125_WJC_METTL3_EV_vs_WT_F06.21150.21150.4 0.0695 15/90 K.APIR[166.11]PDIVNFVHTNLR[166.11].K "sp|P36578|RL4_HUMAN,tr|H3BTP7|H3BTP7_HUMAN,tr|H3BU31|H3BU31_HUMAN" 3 1881.0488 1.07 88600 21150 4 1881.052064 471.2695 60S ribosomal protein L4 OS=Homo sapiens OX=9606 GN=RPL4 PE=1 SV=5 9.65 3296.4 - 431887 - - - 1.74 - 2.781 0.312 - 187.5 1 2 0 0.0033 16 0 0 0 1.03E+07 9.63E+06 - - - 2.301 0.9998 221125_WJC_METTL3_EV_vs_WT_F06.21157.21157.4 0.000429 18/90 K.APIRPDIVNFVHTNLR.K "sp|P36578|RL4_HUMAN,tr|H3BTP7|H3BTP7_HUMAN,tr|H3BU31|H3BU31_HUMAN" 3 1861.0323 1.07 88605 21157 4 1861.034551 466.2653 60S ribosomal protein L4 OS=Homo sapiens OX=9606 GN=RPL4 PE=1 SV=5 9.65 3297.2 - 629761 - - - 1.2359 - 3.018 0.372 - 267.4 1 2 0 0.0023 16 0 0 0 1.03E+07 9.63E+06 - - - 2.8524 1 221125_WJC_METTL3_EV_vs_WT_F06.21160.21160.4 1.46E-11 33/186 K.VGGTNLGAPGAFGQSPFSQPPAPPHQNTFPPR.S sp|Q96I24|FUBP3_HUMAN 1 3227.5901 2.34 88607 21160 4 3227.594167 807.9048 Far upstream element-binding protein 3 OS=Homo sapiens OX=9606 GN=FUBP3 PE=1 SV=2 9.73 3297.5 - 7.93E+06 - - - 1.2663 - 4.902 0.602 - 364.9 1 2 0 0.0041 32 0 0 0 2.80E+08 1.20E+08 - - - 4.9446 1 221125_WJC_METTL3_EV_vs_WT_F06.21162.21162.3 1.04E-05 30/124 K.VGGTNLGAPGAFGQSPFSQPPAPPHQNTFPPR.S sp|Q96I24|FUBP3_HUMAN 1 3227.5901 2.34 88608 21162 3 3227.593055 1076.8706 Far upstream element-binding protein 3 OS=Homo sapiens OX=9606 GN=FUBP3 PE=1 SV=2 9.73 3297.8 - 4.76E+06 - - - 0.9217 - 4.809 0.622 - 505.3 1 2 0 0.003 32 0 0 0 2.42E+08 1.03E+08 - - - 9.087 0.9999 221125_WJC_METTL3_EV_vs_WT_F06.21164.21164.3 4.81E-07 16/64 K.KIGDEYFTFITDC[160.03]KDPK.A "sp|P49368|TCPG_HUMAN,tr|B4DUR8|B4DUR8_HUMAN" 2 2075.9874 0.27 88610 21164 3 2075.990848 693.0031 T-complex protein 1 subunit gamma OS=Homo sapiens OX=9606 GN=CCT3 PE=1 SV=4 4.68 3297.9 - 4.45E+06 - - - 1.6638 - 3.298 0.58 - 218.5 1 2 1 0.0035 17 0 0 0 1.54E+08 5.72E+08 - - - 8.0201 1 221125_WJC_METTL3_EV_vs_WT_F06.21165.21165.2 7.25E-09 15/32 K.SKELTTEIDNNIEQISS.Y "sp|P13645|K1C10_HUMAN,tr|A0A1B0GVI3|A0A1B0GVI3_HUMAN" 2 1919.9324 999 88611 21165 2 1919.934171 960.9735 "Keratin, type I cytoskeletal 10 OS=Homo sapiens OX=9606 GN=KRT10 PE=1 SV=6" 4 3298.1 - 1.12E+06 - - - 0.9323 - 3.248 0.621 - 868.4 1 1 1 0.0018 17 0 0 0 7.45E+07 0.00E+00 - - - 6.5234 0.9999 221125_WJC_METTL3_EV_vs_WT_F06.21166.21166.4 2.11E-06 17/150 K.FLSPVVPNYDNVHPNYHKEPFLQQLK.V "sp|Q9Y262|EIF3L_HUMAN,tr|B0QY89|B0QY89_HUMAN,tr|B0QY90|B0QY90_HUMAN" 3 3122.5978 1.19 88612 21166 4 3122.602035 781.6567 Eukaryotic translation initiation factor 3 subunit L OS=Homo sapiens OX=9606 GN=EIF3L PE=1 SV=1 6.92 3298.2 - 960089 - - - 1.3591 - 3.269 0.575 - 108.1 1 2 1 0.0042 26 0 0 0 1.49E+07 1.25E+07 - - - 4.6033 1 221125_WJC_METTL3_EV_vs_WT_F06.21180.21180.3 1.32E-11 18/68 K.DFDFESANAQFNKEEIDR.E "sp|Q8ND56|LS14A_HUMAN,tr|A0A140TA76|A0A140TA76_HUMAN,tr|K7EMZ9|K7EMZ9_HUMAN" 3 2173.9552 1.08 88621 21180 3 2173.955074 725.659 Protein LSM14 homolog A OS=Homo sapiens OX=9606 GN=LSM14A PE=1 SV=3 4.02 3299.8 - 1.81E+06 - - - -0.0773 - 3.746 0.702 - 304.3 1 2 1 -0.0002 18 0 0 0 3.18E+08 2.95E+08 - - - 9.6552 1 221125_WJC_METTL3_EV_vs_WT_F06.21182.21182.3 1.18E-12 22/88 K.AFQQSVEQDNLFDISTEEGSTK[136.11]R[166.11].K "sp|Q14690|RRP5_HUMAN,tr|A0A3B3IUD7|A0A3B3IUD7_HUMAN" 2 2646.2528 0.81 88623 21182 3 2646.243456 883.0916 Protein RRP5 homolog OS=Homo sapiens OX=9606 GN=PDCD11 PE=1 SV=3 4.18 3300.1 - 438680 - - - -3.5401 - 4.157 0.7 - 470.7 1 2 0 -0.0094 23 0 0 0 2.46E+07 3.04E+07 - - - 9.6842 1 221125_WJC_METTL3_EV_vs_WT_F06.21183.21183.4 2.66E-08 20/90 R.QNVAYEYLC[160.03]HLEEAKR.W "sp|P46940|IQGA1_HUMAN,tr|A0A087X225|A0A087X225_HUMAN,tr|A0A0J9YXZ5|A0A0J9YXZ5_HUMAN" 3 2021.9629 1.05 88624 21183 4 2021.962362 506.498 Ras GTPase-activating-like protein IQGAP1 OS=Homo sapiens OX=9606 GN=IQGAP1 PE=1 SV=1 5.5 3300.2 - 402034 - - - -0.271 - 4.042 0.619 - 514 1 2 0 -0.0005 16 0 0 0 1.61E+07 1.53E+07 - - - 5.1056 0.9457 221125_WJC_METTL3_EV_vs_WT_F06.21184.21184.3 4.96E-05 13/72 A.FLGNSVLGHLENMHPDNSK[136.11].A "sp|Q8IWZ3|ANKH1_HUMAN,tr|A0A0A0MQZ8|A0A0A0MQZ8_HUMAN,tr|H0Y472|H0Y472_HUMAN,tr|H0Y7Y3|H0Y7Y3_HUMAN,tr|H0Y4P6|H0Y4P6_HUMAN,tr|H7C0V5|H7C0V5_HUMAN,tr|H0Y785|H0Y785_HUMAN" 7 2116.0251 0.05 88625 21184 3 2116.029218 706.349 Ankyrin repeat and KH domain-containing protein 1 OS=Homo sapiens OX=9606 GN=ANKHD1 PE=1 SV=1 5.99 3300.4 - 362259 - - - 1.9352 - 2.001 0.359 - 124.6 1 1 0 0.0041 19 0 0 0 2.71E+05 5.33E+06 - - - 4.2455 1 221125_WJC_METTL3_EV_vs_WT_F06.21186.21186.4 5.70E-09 28/186 K.VGGTNLGAPGAFGQSPFSQPPAPPHQNTFPPR[166.11].S sp|Q96I24|FUBP3_HUMAN 1 3237.5984 2.34 88626 21186 4 3237.600892 810.4069 Far upstream element-binding protein 3 OS=Homo sapiens OX=9606 GN=FUBP3 PE=1 SV=2 9.73 3300.6 - 4.23E+06 - - - 0.7851 - 4.203 0.569 - 258.8 1 2 0 0.0025 32 0 0 0 2.80E+08 1.20E+08 - - - 4.6114 1 221125_WJC_METTL3_EV_vs_WT_F06.21190.21190.4 8.07E-11 19/162 K.VQSVETVEGC[160.03]THEVALPAEEDYLPLK[136.11]PR[166.11].V sp|P42285|MTREX_HUMAN 1 3183.5877 0.85 88629 21190 4 3183.587007 796.9042 Exosome RNA helicase MTR4 OS=Homo sapiens OX=9606 GN=MTREX PE=1 SV=3 4.41 3301.1 - 2.04E+06 - - - -0.2177 - 3.823 0.655 - 137.8 1 2 0 -0.0007 28 0 0 0 6.87E+07 8.04E+07 - - - 5.3433 1 221125_WJC_METTL3_EV_vs_WT_F06.21191.21191.4 3.94E-08 22/132 R.IR[166.11]NELMQSLNQDSNSNFK[136.11]DTLLK[136.11].E "sp|Q15643|TRIPB_HUMAN,tr|H0YJ97|H0YJ97_HUMAN" 2 2733.3966 1.57 88630 21191 4 2733.392741 684.3564 Thyroid receptor-interacting protein 11 OS=Homo sapiens OX=9606 GN=TRIP11 PE=1 SV=3 6.12 3301.2 - 1.32E+06 - - - -1.4114 - 4.043 0.639 - 344.5 1 2 2 -0.0039 23 0 0 0 7.03E+07 4.48E+07 - - - 5.2394 0.8494 221125_WJC_METTL3_EV_vs_WT_F06.21192.21192.3 0.465 Oct-64 R.GTNIIC[160.03]YSSVLDRAPR[166.11]R.Q tr|A0A1B0GW58|A0A1B0GW58_HUMAN 1 1987.0297 - 88631 21192 3 1987.033985 663.3505 Voltage-dependent L-type calcium channel subunit beta-4 (Fragment) OS=Homo sapiens OX=9606 GN=CACNB4 PE=1 SV=1 9.5 3301.3 - 660070 - - - 2.1575 - 1.644 0.15 - 46.3 1 2 1 0.0043 17 0 0 0 - - - - - 1.4671 1 221125_WJC_METTL3_EV_vs_WT_F06.21196.21196.3 2.90E-09 33/124 K.VGGTNLGAPGAFGQSPFSQPPAPPHQNTFPPR[166.11].S sp|Q96I24|FUBP3_HUMAN 1 3237.5984 2.34 88633 21196 3 3237.598158 1080.2067 Far upstream element-binding protein 3 OS=Homo sapiens OX=9606 GN=FUBP3 PE=1 SV=2 9.73 3301.7 - 2.33E+06 - - - -0.0593 - 4.308 0.652 - 699.4 1 2 0 -0.0002 32 0 0 0 2.42E+08 1.03E+08 - - - 9.1691 1 221125_WJC_METTL3_EV_vs_WT_F06.21198.21198.4 1.55E-11 26/162 K.VQSVETVEGC[160.03]THEVALPAEEDYLPLKPR.V sp|P42285|MTREX_HUMAN 1 3165.5652 0.85 88635 21198 4 3165.562027 792.3986 Exosome RNA helicase MTR4 OS=Homo sapiens OX=9606 GN=MTREX PE=1 SV=3 4.41 3301.9 - 2.80E+06 - - - -1.0118 - 4.516 0.661 - 162.5 1 2 0 -0.0032 28 0 0 0 6.81E+07 8.02E+07 - - - 5.4465 1 221125_WJC_METTL3_EV_vs_WT_F06.21202.21202.3 2.48E-08 19/88 K.AFQQSVEQDNLFDISTEEGSTKR.K "sp|Q14690|RRP5_HUMAN,tr|A0A3B3IUD7|A0A3B3IUD7_HUMAN" 2 2628.2304 0.78 88639 21202 3 2628.2314 877.0841 Protein RRP5 homolog OS=Homo sapiens OX=9606 GN=PDCD11 PE=1 SV=3 4.18 3302.4 - 902253 - - - 0.398 - 3.521 0.605 - 281 1 2 0 0.001 23 0 0 0 2.37E+07 3.02E+07 - - - 8.2378 0.9985 221125_WJC_METTL3_EV_vs_WT_F06.21203.21203.3 8.53E-06 15/92 K.VAEPPPPPPPHFSETFPSLPAEGK.V sp|Q14549|GBX1_HUMAN 1 2524.2638 20.26 88640 21203 3 2524.272083 842.4286 Homeobox protein GBX-1 OS=Homo sapiens OX=9606 GN=GBX1 PE=1 SV=2 4.75 3302.5 - 588950 - - - 3.2711 - 2.845 0.289 - 173.5 1 2 0 0.0083 24 0 0 0 1.01E+07 5.00E+05 - - - 4.1882 1 221125_WJC_METTL3_EV_vs_WT_F06.21207.21207.4 1.15E-10 31/132 R.IRNELMQSLNQDSNSNFKDTLLK.E "sp|Q15643|TRIPB_HUMAN,tr|H0YJ97|H0YJ97_HUMAN" 2 2707.3599 1.56 88642 21207 4 2707.360332 677.8473 Thyroid receptor-interacting protein 11 OS=Homo sapiens OX=9606 GN=TRIP11 PE=1 SV=3 6.12 3303 - 2.86E+06 - - - 0.1489 - 5.228 0.655 - 678.7 1 2 2 0.0004 23 0 0 0 7.14E+07 4.59E+07 - - - 5.4629 1 221125_WJC_METTL3_EV_vs_WT_F06.21212.21212.3 1.05E-10 29/112 R.SAAGFEPVPEC[160.03]SDGAIHSWAVEGPQPEPR.D sp|Q02413|DSG1_HUMAN 1 3076.3985 999 88645 21212 3 3076.39854 1026.4734 Desmoglein-1 OS=Homo sapiens OX=9606 GN=DSG1 PE=1 SV=2 4.25 3303.5 - 3.99E+06 - - - 0.0133 - 4.375 0.701 - 644.6 1 2 0 0 29 0 0 0 1.36E+08 0.00E+00 - - - 9.751 1 221125_WJC_METTL3_EV_vs_WT_F06.21213.21213.4 3.77E-11 23/102 R.SVTVDSMDEEKIEEYLKR.Q sp|P29084|T2EB_HUMAN 1 2170.0464 1.38 88646 21213 4 2170.048595 543.5189 Transcription initiation factor IIE subunit beta OS=Homo sapiens OX=9606 GN=GTF2E2 PE=1 SV=1 4.36 3303.6 - 1.76E+06 - - - 1.0276 - 3.887 0.667 - 326.3 1 2 1 0.0022 18 0 0 0 1.89E+07 1.36E+07 - - - 5.496 0.9997 221125_WJC_METTL3_EV_vs_WT_F06.21215.21215.3 7.68E-05 Dec-64 R.GKYSEVFEAINITNNEK.V "sp|P68400|CSK21_HUMAN,sp|Q8NEV1|CSK23_HUMAN,tr|A0A2R8YCK2|A0A2R8YCK2_HUMAN,tr|A0A2R8YFU2|A0A2R8YFU2_HUMAN,tr|V9GYA2|V9GYA2_HUMAN,tr|A0A2R8YEW1|A0A2R8YEW1_HUMAN,tr|A0A2R8Y4D6|A0A2R8Y4D6_HUMAN,tr|A0A2R8YD58|A0A2R8YD58_HUMAN,tr|A0A2R8YF43|A0A2R8YF43_HUMAN,tr|A0A2R8Y5A0|A0A2R8Y5A0_HUMAN,tr|A0A2R8YDY7|A0A2R8YDY7_HUMAN,tr|A0A2R8YF47|A0A2R8YF47_HUMAN,tr|A0A2R8Y4H0|A0A2R8Y4H0_HUMAN,tr|A0A2R8Y7T1|A0A2R8Y7T1_HUMAN,tr|A0A2R8YDP2|A0A2R8YDP2_HUMAN,tr|A0A2R8Y797|A0A2R8Y797_HUMAN,tr|A0A2R8YEL7|A0A2R8YEL7_HUMAN,tr|V9GY80|V9GY80_HUMAN,tr|E7EU96|E7EU96_HUMAN,tr|A0A2R8Y3W6|A0A2R8Y3W6_HUMAN" 20 1954.9636 0.95 88648 21215 3 1954.964655 652.6618 Casein kinase II subunit alpha OS=Homo sapiens OX=9606 GN=CSNK2A1 PE=1 SV=1 4.79 3303.8 - 1.07E+06 - - - 0.5284 - 2.437 0.447 - 185.6 1 2 1 0.001 17 0 0 0 1.78E+07 1.88E+07 - - - 5.7737 1 221125_WJC_METTL3_EV_vs_WT_F06.21218.21218.4 6.11E-11 23/90 R.QNVAYEYLC[160.03]HLEEAK[136.11]R[166.11].W "sp|P46940|IQGA1_HUMAN,tr|A0A087X225|A0A087X225_HUMAN,tr|A0A0J9YXZ5|A0A0J9YXZ5_HUMAN" 3 2039.9854 1.05 88649 21218 4 2039.980919 511.0036 Ras GTPase-activating-like protein IQGAP1 OS=Homo sapiens OX=9606 GN=IQGAP1 PE=1 SV=1 5.5 3304.2 - 1.37E+06 - - - -2.1868 - 4.095 0.607 - 720.2 1 2 0 -0.0045 16 0 0 0 1.61E+07 1.53E+07 - - - 5.0047 1 221125_WJC_METTL3_EV_vs_WT_F06.21222.21222.3 0.0414 19/60 K.K[136.11]VSQEILELLNTTTAK[136.11].E "sp|Q86U44|MTA70_HUMAN,tr|H0YFV6|H0YFV6_HUMAN" 2 1803.0324 0 88652 21222 3 1803.031317 602.0181 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 6.14 3304.6 - 2.41E+06 - - - -0.6173 - 3.279 0.524 - 495.9 1 2 0 -0.0011 16 0 0 0 2.15E+05 6.28E+07 - - - 7.4288 1 221125_WJC_METTL3_EV_vs_WT_F06.21228.21228.4 3.66E-10 21/168 R.SAAGFEPVPEC[160.03]SDGAIHSWAVEGPQPEPR.D sp|Q02413|DSG1_HUMAN 1 3076.3985 38.28 88656 21228 4 3076.396115 770.1069 Desmoglein-1 OS=Homo sapiens OX=9606 GN=DSG1 PE=1 SV=2 4.25 3305.3 - 1.88E+06 - - - -0.7749 - 3.773 0.636 - 223.2 1 2 0 -0.0024 29 0 0 0 2.82E+07 7.36E+05 - - - 5.1703 0.9994 221125_WJC_METTL3_EV_vs_WT_F06.21230.21230.4 8.82E-09 23/126 K.HTDESLGDC[160.03]SFLNTC[160.03]FHMDTC[160.03]K[136.11].Y "sp|Q86U44|MTA70_HUMAN,tr|H0YFV6|H0YFV6_HUMAN" 2 2682.0698 0.001 88658 21230 4 2683.068497 671.5247 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 4.64 3305.6 - 2.17E+06 - - - 372.3441 - 4.574 0.625 - 405.6 1 2 0 0.9987 22 0 0 0 0.00E+00 3.01E+07 - - - 4.8868 1 221125_WJC_METTL3_EV_vs_WT_F06.21236.21236.3 1.33E-14 23/88 R.IRNELMQSLNQDSNSNFKDTLLK.E "sp|Q15643|TRIPB_HUMAN,tr|H0YJ97|H0YJ97_HUMAN" 2 2707.3599 2.06 88662 21236 3 2707.363523 903.4606 Thyroid receptor-interacting protein 11 OS=Homo sapiens OX=9606 GN=TRIP11 PE=1 SV=3 6.12 3306.4 - 1.24E+06 - - - 1.3275 - 4.737 0.656 - 674.3 1 2 2 0.0036 23 0 0 0 1.76E+07 8.53E+06 - - - 9.5016 0.9992 221125_WJC_METTL3_EV_vs_WT_F06.21240.21240.4 0.000197 14/96 K.C[160.03]LELFSELAEDK[136.11]ENYK[136.11]K[136.11].F sp|P08238|HS90B_HUMAN 1 2139.062 1.65 88664 21240 4 2139.053456 535.7728 Heat shock protein HSP 90-beta OS=Homo sapiens OX=9606 GN=HSP90AB1 PE=1 SV=4 4.59 3306.9 - 621572 - - - -4.0046 - 2.77 0.513 - 116.7 1 2 1 -0.0086 17 0 0 0 1.33E+07 8.07E+06 - - - 4.0425 1 221125_WJC_METTL3_EV_vs_WT_F06.21248.21248.3 5.06E-12 21/108 R.ALQAGQLENQAAPDDTQGSPDLGAVELR.L "sp|Q16512|PKN1_HUMAN,tr|K7EM57|K7EM57_HUMAN" 2 2863.3948 1.27 88670 21248 3 2863.393882 955.4722 Serine\threonine-protein kinase N1 OS=Homo sapiens OX=9606 GN=PKN1 PE=1 SV=2 3.77 3307.9 - 674383 - - - -0.3185 - 4.053 0.696 - 338.9 1 2 0 -0.0009 28 0 0 0 6.64E+06 5.25E+06 - - - 9.5191 1 221125_WJC_METTL3_EV_vs_WT_F06.21253.21253.4 1.87E-08 20/90 K.K[136.11]VSQEILELLNTTTAK[136.11].E "sp|Q86U44|MTA70_HUMAN,tr|H0YFV6|H0YFV6_HUMAN" 2 1803.0324 0.01 88673 21253 4 1803.029162 451.7654 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 6.14 3308.5 - 1.21E+06 - - - -1.8125 - 2.968 0.602 - 380.5 1 2 0 -0.0033 16 0 0 0 1.76E+05 2.34E+07 - - - 4.8481 1 221125_WJC_METTL3_EV_vs_WT_F06.21254.21254.3 4.71E-08 21/100 K.QGTVSSQPVPFSALGPTEKPGIEIGK.V "sp|Q96KQ4|ASPP1_HUMAN,tr|H0YJL1|H0YJL1_HUMAN,tr|A0A3B3ISJ2|A0A3B3ISJ2_HUMAN" 3 2623.3857 6.29 88674 21254 3 2623.384243 875.4692 Apoptosis-stimulating of p53 protein 1 OS=Homo sapiens OX=9606 GN=PPP1R13B PE=1 SV=3 6.14 3308.7 - 1.12E+06 - - - -0.568 - 3.938 0.605 - 335.3 1 2 0 -0.0015 26 0 0 0 2.12E+07 3.37E+06 - - - 8.4382 1 221125_WJC_METTL3_EV_vs_WT_F06.21268.21268.3 4.37E-12 20/64 K.HTDESLGDC[160.03]SFLNTC[160.03]FH.M "sp|Q86U44|MTA70_HUMAN,tr|H0YFV6|H0YFV6_HUMAN" 2 2038.8149 - 88683 21268 3 2039.814236 680.6123 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 4.52 3310.4 - 978690 - - - 490.1426 - 3.976 0.72 - 614.4 1 1 0 0.9993 17 0 0 0 - - - - - 9.7775 0.957 221125_WJC_METTL3_EV_vs_WT_F06.21271.21271.3 1.52E-06 11/100 K.NGFSSVQATQLQTTQSVEGATGSAVK.S "sp|Q14157|UBP2L_HUMAN,tr|F8W726|F8W726_HUMAN" 2 2595.2776 -1 88686 21271 3 2596.263773 866.0998 Ubiquitin-associated protein 2-like OS=Homo sapiens OX=9606 GN=UBAP2L PE=1 SV=2 6 3310.7 - 844980 - - - 379.9724 - 2.992 0.509 - 91.9 1 2 0 0.9861 26 0 0 0 0.00E+00 0.00E+00 - - - 6.4631 0.998 221125_WJC_METTL3_EV_vs_WT_F06.21274.21274.4 2.76E-08 16/90 R.SPSELFAQHIVTIVHH.V "sp|Q9Y2W1|TR150_HUMAN,tr|A0A3B3ITZ9|A0A3B3ITZ9_HUMAN" 2 1813.9475 - 88689 21274 4 1813.944895 454.4942 Thyroid hormone receptor-associated protein 3 OS=Homo sapiens OX=9606 GN=THRAP3 PE=1 SV=2 6.2 3311.1 - 367410 - - - -1.446 - 2.862 0.58 - 163.1 1 1 0 -0.0026 16 0 0 0 - - - - - 4.644 1 221125_WJC_METTL3_EV_vs_WT_F06.21283.21283.3 7.51E-06 14/72 R.GLLQDDAHPTLVTYADHSK[136.11].L "sp|Q86U44|MTA70_HUMAN,tr|F5H6D8|F5H6D8_HUMAN,tr|H0YFV6|H0YFV6_HUMAN,tr|B4DTN4|B4DTN4_HUMAN" 4 2088.0367 0.57 88696 21283 3 2088.0348 697.0195 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 5.13 3312.1 - 651119 - - - -0.9257 - 2.984 0.45 - 193.6 1 2 0 -0.0019 19 0 0 0 8.83E+06 1.55E+07 - - - 6.2425 0.9986 221125_WJC_METTL3_EV_vs_WT_F06.21284.21284.3 0.0103 10/100 K.QGTVSSQPVPFSALGPTEK[136.11]PGIEIGK[136.11].V "sp|Q96KQ4|ASPP1_HUMAN,tr|H0YJL1|H0YJL1_HUMAN,tr|A0A3B3ISJ2|A0A3B3ISJ2_HUMAN" 3 2639.4141 6.29 88697 21284 3 2639.409197 880.812 Apoptosis-stimulating of p53 protein 1 OS=Homo sapiens OX=9606 GN=PPP1R13B PE=1 SV=3 6.14 3312.3 - 390590 - - - -1.8701 - 2.104 0.285 - 62.7 1 2 0 -0.0049 26 0 0 0 2.12E+07 3.37E+06 - - - 3.4274 1 221125_WJC_METTL3_EV_vs_WT_F06.21288.21288.3 1.49E-11 24/80 R.HNPPDDIGSSFYPELGSYSSR.D "sp|Q5SRI9|MANEA_HUMAN,tr|A0A804HID7|A0A804HID7_HUMAN,tr|A0A804HHU5|A0A804HHU5_HUMAN,tr|X6R7A2|X6R7A2_HUMAN" 4 2324.0346 2.02 88699 21288 3 2324.035236 775.6855 "Glycoprotein endo-alpha-1,2-mannosidase OS=Homo sapiens OX=9606 GN=MANEA PE=1 SV=1" 4.54 3312.8 - 1.58E+06 - - - 0.293 - 4.146 0.64 - 499 1 2 0 0.0007 21 0 0 0 6.80E+07 3.36E+07 - - - 9.0847 1 221125_WJC_METTL3_EV_vs_WT_F06.21289.21289.3 1.63E-06 18/84 K.VTINDLNENSVTLIQENC[160.03]HLNK[136.11].L sp|Q7Z2T5|TRM1L_HUMAN 1 2575.2792 0.7 88700 21289 3 2575.28179 859.4337 TRMT1-like protein OS=Homo sapiens OX=9606 GN=TRMT1L PE=1 SV=2 4.65 3312.9 - 2.00E+06 - - - 1.0189 - 3.607 0.623 - 332 1 2 0 0.0026 22 0 0 0 1.67E+07 2.38E+07 - - - 8.5266 1 221125_WJC_METTL3_EV_vs_WT_F06.21290.21290.3 1.24E-08 19/84 K.VTINDLNENSVTLIQENC[160.03]HLNK.L sp|Q7Z2T5|TRM1L_HUMAN 1 2567.265 0.69 88701 21290 3 2567.265957 856.7623 TRMT1-like protein OS=Homo sapiens OX=9606 GN=TRMT1L PE=1 SV=2 4.65 3313 - 1.35E+06 - - - 0.386 - 4.417 0.646 - 401.5 1 2 0 0.001 22 0 0 0 1.64E+07 2.38E+07 - - - 9.2638 0.9599 221125_WJC_METTL3_EV_vs_WT_F06.21291.21291.3 2.30E-05 17/100 K.NGFSSVQATQLQTTQSVEGATGSAVK[136.11].S "sp|Q14157|UBP2L_HUMAN,tr|F8W726|F8W726_HUMAN" 2 2603.2918 -1 88702 21291 3 2604.277579 868.7712 Ubiquitin-associated protein 2-like OS=Homo sapiens OX=9606 GN=UBAP2L PE=1 SV=2 6 3313.1 - 1.23E+06 - - - 378.6514 - 3.178 0.515 - 283 1 2 0 0.9857 26 0 0 0 0.00E+00 0.00E+00 - - - 6.6688 0.9999 221125_WJC_METTL3_EV_vs_WT_F06.21294.21294.3 1.70E-06 17/84 R.K[136.11]SEALLGFSVENAAATQVTSAK[136.11].E "sp|Q86UP3|ZFHX4_HUMAN,tr|E5RHS1|E5RHS1_HUMAN,tr|E5RGK3|E5RGK3_HUMAN,tr|E5RG79|E5RG79_HUMAN,tr|E5RI93|E5RI93_HUMAN,tr|E7EVZ1|E7EVZ1_HUMAN" 6 2237.1874 1.23 88705 21294 3 2237.181785 746.7364 Zinc finger homeobox protein 4 OS=Homo sapiens OX=9606 GN=ZFHX4 PE=1 SV=1 6.14 3313.5 - 505717 - - - -2.5219 - 3.256 0.512 - 293.5 1 2 0 -0.0056 22 0 0 0 1.52E+07 1.24E+07 - - - 7.0455 1 221125_WJC_METTL3_EV_vs_WT_F06.21299.21299.3 2.14E-09 25/80 K.WQHDLFDSGFGGGAGVETGGK[136.11].L "sp|Q86V81|THOC4_HUMAN,tr|E9PB61|E9PB61_HUMAN" 2 2128.9694 0.71 88708 21299 3 2128.968828 710.6637 THO complex subunit 4 OS=Homo sapiens OX=9606 GN=ALYREF PE=1 SV=3 4.54 3314.2 - 4.06E+06 - - - -0.2602 - 3.84 0.574 - 738.9 1 2 0 -0.0006 21 0 0 0 4.08E+07 5.76E+07 - - - 8.1651 1 221125_WJC_METTL3_EV_vs_WT_F06.21301.21301.3 4.11E-12 19/76 K.C[160.03]TTDENK[136.11]VPYFNAPVYLENK[136.11].E sp|Q9NY12|GAR1_HUMAN 1 2417.1544 1.26 88710 21301 3 2417.156594 806.7254 H\ACA ribonucleoprotein complex subunit 1 OS=Homo sapiens OX=9606 GN=GAR1 PE=1 SV=1 4.68 3314.4 - 9.03E+06 - - - 0.9023 - 3.542 0.667 - 275.5 1 2 1 0.0022 20 0 0 0 4.56E+08 3.62E+08 - - - 9.044 1 221125_WJC_METTL3_EV_vs_WT_F06.21302.21302.3 8.84E-10 24/80 R.HNPPDDIGSSFYPELGSYSSR[166.11].D "sp|Q5SRI9|MANEA_HUMAN,tr|A0A804HID7|A0A804HID7_HUMAN,tr|A0A804HHU5|A0A804HHU5_HUMAN,tr|X6R7A2|X6R7A2_HUMAN" 4 2334.0428 2.03 88711 21302 3 2334.047089 779.0216 "Glycoprotein endo-alpha-1,2-mannosidase OS=Homo sapiens OX=9606 GN=MANEA PE=1 SV=1" 4.54 3314.5 - 1.23E+06 - - - 1.8269 - 4.334 0.646 - 533.3 1 2 0 0.0043 21 0 0 0 6.79E+07 3.35E+07 - - - 9.2569 0.9999 221125_WJC_METTL3_EV_vs_WT_F06.21304.21304.3 2.36E-07 21/72 R.HSQELPAILDDTTLSGSDR[166.11].N "sp|Q15021|CND1_HUMAN,tr|F5GZK7|F5GZK7_HUMAN" 2 2063.9999 0.79 88713 21304 3 2064.009255 689.0072 Condensin complex subunit 1 OS=Homo sapiens OX=9606 GN=NCAPD2 PE=1 SV=3 4.22 3314.7 - 1.10E+06 - - - 4.5339 - 3.891 0.563 - 746.4 1 2 0 0.0094 19 0 0 0 1.63E+07 2.05E+07 - - - 8.1523 1 221125_WJC_METTL3_EV_vs_WT_F06.21305.21305.4 2.64E-10 25/132 R.APDELHYTYLDTFGRPVIVAYKK.N "sp|P04843|RPN1_HUMAN,tr|B7Z4L4|B7Z4L4_HUMAN" 2 2695.401 1.44 88714 21305 4 2695.405135 674.8575 Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit 1 OS=Homo sapiens OX=9606 GN=RPN1 PE=1 SV=1 6.8 3314.8 - 985040 - - - 1.5382 - 3.975 0.633 - 460.2 1 2 0 0.0041 23 0 0 0 3.44E+07 2.38E+07 - - - 5.1816 1 221125_WJC_METTL3_EV_vs_WT_F06.21307.21307.3 5.70E-11 22/72 R.HSQELPAILDDTTLSGSDR.N "sp|Q15021|CND1_HUMAN,tr|F5GZK7|F5GZK7_HUMAN" 2 2053.9916 0.79 88716 21307 3 2053.995112 685.6712 Condensin complex subunit 1 OS=Homo sapiens OX=9606 GN=NCAPD2 PE=1 SV=3 4.22 3315.1 - 872570 - - - 1.6967 - 4.096 0.625 - 896.5 1 2 0 0.0035 19 0 0 0 1.63E+07 2.05E+07 - - - 8.9713 1 221125_WJC_METTL3_EV_vs_WT_F06.21308.21308.2 5.80E-13 18/32 K.HTDESLGDC[160.03]SFLNTC[160.03]FH.M "sp|Q86U44|MTA70_HUMAN,tr|H0YFV6|H0YFV6_HUMAN" 2 2038.8149 - 88717 21308 2 2039.815894 1020.4147 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 4.52 3315.2 - 702733 - - - 490.9558 - 3.98 0.721 - 612.3 1 1 0 1.001 17 0 0 0 - - - - - 7.4479 1 221125_WJC_METTL3_EV_vs_WT_F06.21309.21309.3 5.30E-14 20/104 K.LAFPGETLSDIPC[160.03]KTEEEGVGC[160.03]GGAGR.R sp|Q13111|CAF1A_HUMAN 1 2806.2902 1.01 88718 21309 3 2806.287668 936.4373 Chromatin assembly factor 1 subunit A OS=Homo sapiens OX=9606 GN=CHAF1A PE=1 SV=3 4.25 3315.4 - 539972 - - - -0.9005 - 3.718 0.695 - 328.4 1 2 1 -0.0025 27 0 0 0 7.60E+06 7.55E+06 - - - 9.309 0.9996 221125_WJC_METTL3_EV_vs_WT_F06.21310.21310.2 0.0114 14-Aug K.VFLENVIR[166.11].D sp|P62805|H4_HUMAN 1 998.5788 1.4 88719 21310 2 998.579377 500.2967 Histone H4 OS=Homo sapiens OX=9606 GN=H4C1 PE=1 SV=2 5.97 3315.5 - 447654 - - - 0.5418 - 1.666 0.376 - 237.9 1 2 0 0.0005 8 0 0 0 8.07E+06 5.77E+06 - - - 3.3574 0.9996 221125_WJC_METTL3_EV_vs_WT_F06.21311.21311.3 0.0447 18/52 K.ILLAELEQLKGQGK.S "sp|P08670|VIME_HUMAN,tr|B0YJC4|B0YJC4_HUMAN,tr|A0A1B0GTT5|A0A1B0GTT5_HUMAN" 3 1538.9032 2.32 88720 21311 3 1538.907833 513.975 Vimentin OS=Homo sapiens OX=9606 GN=VIM PE=1 SV=4 6.14 3315.6 - 341108 - - - 3.0151 - 3.237 0.484 - 438.6 1 2 1 0.0046 14 0 0 0 1.04E+07 4.49E+06 - - - 7.0565 1 221125_WJC_METTL3_EV_vs_WT_F06.21315.21315.3 2.49E-12 22/80 K.WQHDLFDSGFGGGAGVETGGK.L "sp|Q86V81|THOC4_HUMAN,tr|E9PB61|E9PB61_HUMAN" 2 2120.9552 0.69 88722 21315 3 2120.955685 707.9923 THO complex subunit 4 OS=Homo sapiens OX=9606 GN=ALYREF PE=1 SV=3 4.54 3316.1 - 3.50E+06 - - - 0.2372 - 3.649 0.677 - 619.5 1 2 0 0.0005 21 0 0 0 4.08E+07 5.94E+07 - - - 9.1911 1 221125_WJC_METTL3_EV_vs_WT_F06.21319.21319.2 4.44E-14 18/38 R.GSGSQSSVPSVDQFTGVGIR[166.11].V sp|Q9UQE7|SMC3_HUMAN 1 1973.9682 0.82 88726 21319 2 1973.966727 987.9914 Structural maintenance of chromosomes protein 3 OS=Homo sapiens OX=9606 GN=SMC3 PE=1 SV=2 5.84 3316.5 - 722781 - - - -0.7477 - 3.727 0.738 - 419 1 2 0 -0.0015 20 0 0 0 1.49E+07 1.83E+07 - - - 7.7259 1 221125_WJC_METTL3_EV_vs_WT_F06.21328.21328.3 2.23E-09 16/76 R.GSGSQSSVPSVDQFTGVGIR[166.11].V sp|Q9UQE7|SMC3_HUMAN 1 1973.9682 0.9 88733 21328 3 1973.967396 658.9967 Structural maintenance of chromosomes protein 3 OS=Homo sapiens OX=9606 GN=SMC3 PE=1 SV=2 5.84 3317.5 - 1.22E+06 - - - -0.4088 - 2.915 0.545 - 235.7 1 2 0 -0.0008 20 0 0 0 1.89E+07 2.12E+07 - - - 7.2115 1 221125_WJC_METTL3_EV_vs_WT_F06.21329.21329.3 6.76E-09 17/76 K.SESEVEEAAAIIAQR[166.11]PDNPR[166.11].E "sp|Q16643|DREB_HUMAN,tr|D6R9Q9|D6R9Q9_HUMAN,tr|D6R9W4|D6R9W4_HUMAN" 3 2201.0827 1.38 88734 21329 3 2201.082148 734.7015 Drebrin OS=Homo sapiens OX=9606 GN=DBN1 PE=1 SV=4 4.25 3317.6 - 1.09E+06 - - - -0.264 - 3.075 0.606 - 412.7 1 2 0 -0.0006 20 0 0 0 2.00E+07 1.45E+07 - - - 8.0213 1 221125_WJC_METTL3_EV_vs_WT_F06.21330.21330.3 6.46E-10 22/100 R.QLLSDYGPPSLGYTQGTGNSQVPQSK.Y "sp|O14519|CDKA1_HUMAN,tr|F5GZF0|F5GZF0_HUMAN" 2 2721.3246 1.42 88735 21330 3 2721.327562 908.1155 Cyclin-dependent kinase 2-associated protein 1 OS=Homo sapiens OX=9606 GN=CDK2AP1 PE=1 SV=1 5.83 3317.8 - 930444 - - - 1.0925 - 4.159 0.663 - 235 1 2 0 0.003 26 0 0 0 1.80E+08 1.27E+08 - - - 9.21 1 221125_WJC_METTL3_EV_vs_WT_F06.21341.21341.2 1.36E-12 17/38 R.GSGSQSSVPSVDQFTGVGIR.V sp|Q9UQE7|SMC3_HUMAN 1 1963.9599 0.82 88744 21341 2 1963.960718 982.9872 Structural maintenance of chromosomes protein 3 OS=Homo sapiens OX=9606 GN=SMC3 PE=1 SV=2 5.84 3319 - 1.14E+06 - - - 0.3997 - 3.591 0.724 - 324 1 2 0 0.0008 20 0 0 0 1.49E+07 1.83E+07 - - - 7.5313 1 221125_WJC_METTL3_EV_vs_WT_F06.21343.21343.3 4.10E-11 15/96 K.LVQDVANNTNEEAGDGTTTATVLAR.S "sp|P10809|CH60_HUMAN,tr|C9JL25|C9JL25_HUMAN,tr|A0A7I2V2X6|A0A7I2V2X6_HUMAN,tr|A0A7I2YQK6|A0A7I2YQK6_HUMAN,tr|A0A7I2V599|A0A7I2V599_HUMAN,tr|E7EXB4|E7EXB4_HUMAN,tr|A0A7I2YQ71|A0A7I2YQ71_HUMAN,tr|E7ESH4|E7ESH4_HUMAN,tr|A0A7I2V5M1|A0A7I2V5M1_HUMAN,tr|A0A7I2V5K3|A0A7I2V5K3_HUMAN,tr|A0A7I2V369|A0A7I2V369_HUMAN" 11 2559.2413 1.27 88746 21343 3 2559.242435 854.0877 "60 kDa heat shock protein, mitochondrial OS=Homo sapiens OX=9606 GN=HSPD1 PE=1 SV=2" 3.92 3319.3 - 480359 - - - 0.4619 - 3.128 0.65 - 284.7 1 2 0 0.0012 25 0 0 0 1.45E+07 1.14E+07 - - - 8.4102 0.9998 221125_WJC_METTL3_EV_vs_WT_F06.21348.21348.3 1.03E-05 16/100 R.QLLSDYGPPSLGYTQGTGNSQVPQSK[136.11].Y "sp|O14519|CDKA1_HUMAN,tr|F5GZF0|F5GZF0_HUMAN" 2 2729.3388 1.41 88749 21348 3 2729.336105 910.7869 Cyclin-dependent kinase 2-associated protein 1 OS=Homo sapiens OX=9606 GN=CDK2AP1 PE=1 SV=1 5.83 3319.9 - 2.18E+06 - - - -0.9834 - 2.463 0.367 - 115 1 2 0 -0.0027 26 0 0 0 1.80E+08 1.27E+08 - - - 4.7047 1 221125_WJC_METTL3_EV_vs_WT_F06.21349.21349.3 1.74E-10 20/92 R.VGEAFHASSTSVLVDGFTDPSNNK.S "sp|Q99717|SMAD5_HUMAN,sp|Q15797|SMAD1_HUMAN,tr|H0YAK7|H0YAK7_HUMAN" 3 2478.1663 1.48 88750 21349 3 2478.159721 827.0627 Mothers against decapentaplegic homolog 5 OS=Homo sapiens OX=9606 GN=SMAD5 PE=1 SV=1 4.54 3320 - 1.04E+07 - - - -2.6536 - 3.593 0.604 - 265.7 1 2 0 -0.0066 24 0 0 0 2.31E+08 1.55E+08 - - - 8.2428 0.9994 221125_WJC_METTL3_EV_vs_WT_F06.21350.21350.3 0.00103 Oct-76 R.NVNNEVHFFENNNFNTIANK[136.11].L "sp|Q9BY44|EIF2A_HUMAN,tr|F8WAE5|F8WAE5_HUMAN" 2 2386.1182 0.4 88751 21350 3 2386.114819 796.38 Eukaryotic translation initiation factor 2A OS=Homo sapiens OX=9606 GN=EIF2A PE=1 SV=3 5.4 3320.1 - 1.17E+06 - - - -1.4052 - 2.034 0.317 - 60.8 1 2 0 -0.0034 20 0 0 0 2.43E+07 6.11E+07 - - - 3.7958 0.9999 221125_WJC_METTL3_EV_vs_WT_F06.21351.21351.3 1.58E-05 14/44 R.AR[166.11]FEELNADLFR[166.11].G "sp|P54652|HSP72_HUMAN,sp|P11142|HSP7C_HUMAN,tr|E9PNE6|E9PNE6_HUMAN,tr|A8K7Q2|A8K7Q2_HUMAN,tr|E9PKE3|E9PKE3_HUMAN,tr|E9PN89|E9PN89_HUMAN" 6 1499.7636 0.15 88752 21351 3 1499.762519 500.9285 Heat shock-related 70 kDa protein 2 OS=Homo sapiens OX=9606 GN=HSPA2 PE=1 SV=1 4.68 3320.2 - 1.01E+06 - - - -0.6988 - 2.712 0.49 - 408.2 1 2 1 -0.001 12 0 0 0 1.17E+07 8.00E+07 - - - 6.7682 1 221125_WJC_METTL3_EV_vs_WT_F06.21363.21363.2 1.70E-06 17/50 K.NGFSSVQATQLQTTQSVEGATGSAVK.S "sp|Q14157|UBP2L_HUMAN,tr|F8W726|F8W726_HUMAN" 2 2595.2776 -1 88760 21363 2 2596.259208 1298.6461 Ubiquitin-associated protein 2-like OS=Homo sapiens OX=9606 GN=UBAP2L PE=1 SV=2 6 3321.8 - 973741 - - - 378.2135 - 3.999 0.675 - 767.9 1 2 0 0.9816 26 0 0 0 0.00E+00 0.00E+00 - - - 7.126 1 221125_WJC_METTL3_EV_vs_WT_F06.21372.21372.2 7.09E-11 19/50 K.NGFSSVQATQLQTTQSVEGATGSAVK[136.11].S "sp|Q14157|UBP2L_HUMAN,tr|F8W726|F8W726_HUMAN" 2 2603.2918 -1 88767 21372 2 2604.272094 1302.6532 Ubiquitin-associated protein 2-like OS=Homo sapiens OX=9606 GN=UBAP2L PE=1 SV=2 6 3323 - 616796 - - - 376.5444 - 4.027 0.693 - 1050.9 1 2 0 0.9803 26 0 0 0 0.00E+00 0.00E+00 - - - 7.2765 0.998 221125_WJC_METTL3_EV_vs_WT_F06.21373.21373.2 0.000165 22-Nov R.AR[166.11]FEELNADLFR[166.11].G "sp|P54652|HSP72_HUMAN,sp|P11142|HSP7C_HUMAN,tr|E9PNE6|E9PNE6_HUMAN,tr|A8K7Q2|A8K7Q2_HUMAN,tr|E9PKE3|E9PKE3_HUMAN,tr|E9PN89|E9PN89_HUMAN" 6 1499.7636 0.03 88768 21373 2 1499.764641 750.8891 Heat shock-related 70 kDa protein 2 OS=Homo sapiens OX=9606 GN=HSPA2 PE=1 SV=1 4.68 3323.1 - 417371 - - - 0.7161 - 2.34 0.436 - 185.7 1 2 1 0.0011 12 0 0 0 3.51E+05 1.08E+07 - - - 4.4979 0.9997 221125_WJC_METTL3_EV_vs_WT_F06.21378.21378.3 0.000151 Nov-44 R.ARFEELNADLFR.G "sp|P54652|HSP72_HUMAN,sp|P11142|HSP7C_HUMAN,tr|E9PNE6|E9PNE6_HUMAN,tr|A8K7Q2|A8K7Q2_HUMAN,tr|E9PKE3|E9PKE3_HUMAN,tr|E9PN89|E9PN89_HUMAN" 6 1479.747 0.15 88770 21378 3 1479.748802 494.2563 Heat shock-related 70 kDa protein 2 OS=Homo sapiens OX=9606 GN=HSPA2 PE=1 SV=1 4.68 3323.8 - 614867 - - - 1.1995 - 2.501 0.431 - 254.9 1 2 1 0.0018 12 0 0 0 1.17E+07 8.00E+07 - - - 5.8857 1 221125_WJC_METTL3_EV_vs_WT_F06.21382.21382.4 1.32E-05 13/108 R.GLLQDDAHPTLVTYADHSK[136.11].L "sp|Q86U44|MTA70_HUMAN,tr|F5H6D8|F5H6D8_HUMAN,tr|H0YFV6|H0YFV6_HUMAN,tr|B4DTN4|B4DTN4_HUMAN" 4 2088.0367 0.01 88772 21382 4 2088.034617 523.0165 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 5.13 3324.2 - 1.66E+06 - - - -1.0134 - 2.669 0.513 - 158.5 1 2 0 -0.0021 19 0 0 0 3.22E+05 4.48E+07 - - - 4.0227 1 221125_WJC_METTL3_EV_vs_WT_F06.21384.21384.4 1.43E-08 16/96 K.QEVPSWLENMAYEHHYK[136.11].G "sp|O00571|DDX3X_HUMAN,sp|O15523|DDX3Y_HUMAN,tr|A0A2R8YFR4|A0A2R8YFR4_HUMAN,tr|A0A2R8YCW1|A0A2R8YCW1_HUMAN,tr|A0A2R8YDT5|A0A2R8YDT5_HUMAN,tr|A0A2R8Y645|A0A2R8Y645_HUMAN,tr|A0A2R8YF78|A0A2R8YF78_HUMAN,tr|A0A0D9SFB3|A0A0D9SFB3_HUMAN,tr|A0A2R8YFS5|A0A2R8YFS5_HUMAN,tr|A0A0D9SF53|A0A0D9SF53_HUMAN,tr|A0A087WVZ1|A0A087WVZ1_HUMAN,tr|A0A0J9YVQ7|A0A0J9YVQ7_HUMAN,tr|A0A2R8Y5G6|A0A2R8Y5G6_HUMAN,tr|A0A2R8Y7T2|A0A2R8Y7T2_HUMAN,tr|A0A0D9SG12|A0A0D9SG12_HUMAN,tr|F6S8Q4|F6S8Q4_HUMAN,tr|A0A2U3TZJ9|A0A2U3TZJ9_HUMAN,tr|A0A2R8Y4A4|A0A2R8Y4A4_HUMAN" 18 2167.9877 1.25 88774 21384 4 2167.987254 543.0042 ATP-dependent RNA helicase DDX3X OS=Homo sapiens OX=9606 GN=DDX3X PE=1 SV=3 5.33 3324.5 - 1.00E+06 - - - -0.1942 - 3.52 0.565 - 192.2 1 2 0 -0.0004 17 0 0 0 1.63E+08 1.31E+08 - - - 4.5806 0.9999 221125_WJC_METTL3_EV_vs_WT_F06.21389.21389.4 0.00386 13/132 K.SWASLFHDSK[136.11]PSSSSPVAYVETK[136.11].Y sp|Q14694|UBP10_HUMAN 1 2525.2409 0.93 88777 21389 4 2525.24564 632.3175 Ubiquitin carboxyl-terminal hydrolase 10 OS=Homo sapiens OX=9606 GN=USP10 PE=1 SV=2 6.47 3325.1 - 442596 - - - 1.8695 - 2.09 0.439 - 90.2 1 2 0 0.0047 23 0 0 0 9.45E+06 1.02E+07 - - - 3.2846 1 221125_WJC_METTL3_EV_vs_WT_F06.21390.21390.4 2.15E-06 18/96 K.QEVPSWLENMAYEHHYK.G "sp|O00571|DDX3X_HUMAN,sp|O15523|DDX3Y_HUMAN,tr|A0A2R8YFR4|A0A2R8YFR4_HUMAN,tr|A0A2R8YCW1|A0A2R8YCW1_HUMAN,tr|A0A2R8YDT5|A0A2R8YDT5_HUMAN,tr|A0A2R8Y645|A0A2R8Y645_HUMAN,tr|A0A2R8YF78|A0A2R8YF78_HUMAN,tr|A0A0D9SFB3|A0A0D9SFB3_HUMAN,tr|A0A2R8YFS5|A0A2R8YFS5_HUMAN,tr|A0A0D9SF53|A0A0D9SF53_HUMAN,tr|A0A087WVZ1|A0A087WVZ1_HUMAN,tr|A0A0J9YVQ7|A0A0J9YVQ7_HUMAN,tr|A0A2R8Y5G6|A0A2R8Y5G6_HUMAN,tr|A0A2R8Y7T2|A0A2R8Y7T2_HUMAN,tr|A0A0D9SG12|A0A0D9SG12_HUMAN,tr|F6S8Q4|F6S8Q4_HUMAN,tr|A0A2U3TZJ9|A0A2U3TZJ9_HUMAN,tr|A0A2R8Y4A4|A0A2R8Y4A4_HUMAN" 18 2159.9735 1.25 88778 21390 4 2159.977209 541.0006 ATP-dependent RNA helicase DDX3X OS=Homo sapiens OX=9606 GN=DDX3X PE=1 SV=3 5.33 3325.2 - 1.13E+06 - - - 1.7287 - 3.334 0.516 - 280.1 1 2 0 0.0037 17 0 0 0 1.64E+08 1.31E+08 - - - 4.1343 1 221125_WJC_METTL3_EV_vs_WT_F06.21391.21391.4 8.41E-07 18/102 K.WK[136.11]PPMIDNPSYQGIWK[136.11]PR[166.11].K "sp|P27824|CALX_HUMAN,tr|A0A7P0T937|A0A7P0T937_HUMAN,tr|A0A7P0T840|A0A7P0T840_HUMAN,tr|A0A7P0TB65|A0A7P0TB65_HUMAN,tr|A0A7P0TAE9|A0A7P0TAE9_HUMAN,tr|D6RGY2|D6RGY2_HUMAN,tr|A0A7P0T8G1|A0A7P0T8G1_HUMAN,tr|A0A7P0Z4D6|A0A7P0Z4D6_HUMAN,tr|A0A7P0T9L0|A0A7P0T9L0_HUMAN" 9 2238.1618 1.16 88779 21391 4 2238.161752 560.5477 Calnexin OS=Homo sapiens OX=9606 GN=CANX PE=1 SV=2 9.7 3325.3 - 751036 - - - -0.0371 - 3.018 0.486 - 165 1 2 0 -0.0001 18 0 0 0 4.41E+07 3.80E+07 - - - 3.8345 1 221125_WJC_METTL3_EV_vs_WT_F06.21396.21396.3 1.38E-11 24/112 S.LTSFGTETSNSGTLPQSSAVGSAFTQDTR[166.11].S "sp|Q8ND56|LS14A_HUMAN,tr|A0A140TA76|A0A140TA76_HUMAN,tr|K7EMZ9|K7EMZ9_HUMAN" 3 2956.3926 1.02 88782 21396 3 2956.391411 986.4715 Protein LSM14 homolog A OS=Homo sapiens OX=9606 GN=LSM14A PE=1 SV=3 4.37 3326 - 1.04E+06 - - - -0.3883 - 4.167 0.621 - 403.7 1 1 0 -0.0011 29 0 0 0 7.46E+07 7.33E+07 - - - 8.7467 1 221125_WJC_METTL3_EV_vs_WT_F06.21403.21403.3 6.37E-11 21/76 K.DK[136.11]YPNLQVIGGNVVTAAQAK[136.11].N "sp|P12268|IMDH2_HUMAN,tr|A0A7I2YQK5|A0A7I2YQK5_HUMAN,tr|H0Y4R1|H0Y4R1_HUMAN,tr|A0A7I2V2T3|A0A7I2V2T3_HUMAN,tr|E7ETK5|E7ETK5_HUMAN" 5 2101.1503 0.77 88787 21403 3 2101.149895 701.3907 Inosine-5'-monophosphate dehydrogenase 2 OS=Homo sapiens OX=9606 GN=IMPDH2 PE=1 SV=2 8.5 3326.9 - 3.26E+06 - - - -0.1709 - 3.796 0.622 - 464.9 1 2 1 -0.0004 20 0 0 0 1.68E+08 2.19E+08 - - - 8.7108 1 221125_WJC_METTL3_EV_vs_WT_F06.21405.21405.4 2.15E-10 25/132 K.K[136.11]PALGFYDTSEENYQALDADFR[166.11]K[136.11].L sp|Q99459|CDC5L_HUMAN 1 2703.3027 1.46 88789 21405 4 2703.302646 676.8329 Cell division cycle 5-like protein OS=Homo sapiens OX=9606 GN=CDC5L PE=1 SV=2 4.44 3327.1 - 4.38E+06 - - - -0.0129 - 4.456 0.657 - 565.3 1 2 0 0 23 0 0 0 1.42E+08 9.69E+07 - - - 5.4286 1 221125_WJC_METTL3_EV_vs_WT_F06.21407.21407.3 2.18E-10 24/112 S.LTSFGTETSNSGTLPQSSAVGSAFTQDTR.S "sp|Q8ND56|LS14A_HUMAN,tr|A0A140TA76|A0A140TA76_HUMAN,tr|K7EMZ9|K7EMZ9_HUMAN" 3 2946.3843 1.02 88791 21407 3 2946.383021 983.1354 Protein LSM14 homolog A OS=Homo sapiens OX=9606 GN=LSM14A PE=1 SV=3 4.37 3327.3 - 1.69E+06 - - - -0.4304 - 3.863 0.622 - 404.3 1 1 0 -0.0013 29 0 0 0 7.46E+07 7.33E+07 - - - 8.5835 1 221125_WJC_METTL3_EV_vs_WT_F06.21409.21409.3 9.72E-15 32/88 K.KPALGFYDTSEENYQALDADFRK.L sp|Q99459|CDC5L_HUMAN 1 2677.266 1.24 88793 21409 3 2677.263874 893.4293 Cell division cycle 5-like protein OS=Homo sapiens OX=9606 GN=CDC5L PE=1 SV=2 4.44 3327.6 - 905833 - - - -0.7982 - 5.171 0.74 - 1163.7 1 2 0 -0.0021 23 0 0 0 2.24E+07 1.80E+07 - - - 10.6442 1 221125_WJC_METTL3_EV_vs_WT_F06.21412.21412.4 3.54E-19 35/132 K.KPALGFYDTSEENYQALDADFRK.L sp|Q99459|CDC5L_HUMAN 1 2677.266 1.46 88794 21412 4 2677.266687 670.3238 Cell division cycle 5-like protein OS=Homo sapiens OX=9606 GN=CDC5L PE=1 SV=2 4.44 3328 - 8.31E+06 - - - 0.2525 - 5.678 0.725 - 1265.9 1 2 0 0.0007 23 0 0 0 1.42E+08 9.71E+07 - - - 6.0988 1 221125_WJC_METTL3_EV_vs_WT_F06.21413.21413.3 2.93E-11 34/124 K.VGGTNLGAPGAFGQSPFSQPPAPPHQNTFPPR.S sp|Q96I24|FUBP3_HUMAN 1 3227.5901 2.39 88795 21413 3 3227.589896 1076.8706 Far upstream element-binding protein 3 OS=Homo sapiens OX=9606 GN=FUBP3 PE=1 SV=2 9.73 3328.1 - 3.87E+06 - - - -0.057 - 4.844 0.678 - 725.7 1 2 0 -0.0002 32 0 0 0 1.47E+08 6.12E+07 - - - 9.7288 1 221125_WJC_METTL3_EV_vs_WT_F06.21414.21414.3 1.03E-08 20/76 K.DKYPNLQVIGGNVVTAAQAK.N "sp|P12268|IMDH2_HUMAN,tr|A0A7I2YQK5|A0A7I2YQK5_HUMAN,tr|H0Y4R1|H0Y4R1_HUMAN,tr|A0A7I2V2T3|A0A7I2V2T3_HUMAN,tr|E7ETK5|E7ETK5_HUMAN" 5 2085.1219 0.77 88796 21414 3 2085.122924 696.0479 Inosine-5'-monophosphate dehydrogenase 2 OS=Homo sapiens OX=9606 GN=IMPDH2 PE=1 SV=2 8.5 3328.2 - 3.29E+06 - - - 0.5132 - 3.833 0.627 - 506 1 2 1 0.0011 20 0 0 0 1.68E+08 2.19E+08 - - - 8.7899 1 221125_WJC_METTL3_EV_vs_WT_F06.21417.21417.3 2.72E-15 25/88 K.K[136.11]PALGFYDTSEENYQALDADFR[166.11]K[136.11].L sp|Q99459|CDC5L_HUMAN 1 2703.3027 1.24 88799 21417 3 2703.299965 902.1082 Cell division cycle 5-like protein OS=Homo sapiens OX=9606 GN=CDC5L PE=1 SV=2 4.44 3328.5 - 845842 - - - -1.0047 - 4.811 0.721 - 670 1 2 0 -0.0027 23 0 0 0 2.24E+07 1.80E+07 - - - 10.2629 1 221125_WJC_METTL3_EV_vs_WT_F06.21422.21422.3 4.30E-06 18/64 K.QEVPSWLENMAYEHHYK.G "sp|O00571|DDX3X_HUMAN,sp|O15523|DDX3Y_HUMAN,tr|A0A2R8YFR4|A0A2R8YFR4_HUMAN,tr|A0A2R8YCW1|A0A2R8YCW1_HUMAN,tr|A0A2R8YDT5|A0A2R8YDT5_HUMAN,tr|A0A2R8Y645|A0A2R8Y645_HUMAN,tr|A0A2R8YF78|A0A2R8YF78_HUMAN,tr|A0A0D9SFB3|A0A0D9SFB3_HUMAN,tr|A0A2R8YFS5|A0A2R8YFS5_HUMAN,tr|A0A0D9SF53|A0A0D9SF53_HUMAN,tr|A0A087WVZ1|A0A087WVZ1_HUMAN,tr|A0A0J9YVQ7|A0A0J9YVQ7_HUMAN,tr|A0A2R8Y5G6|A0A2R8Y5G6_HUMAN,tr|A0A2R8Y7T2|A0A2R8Y7T2_HUMAN,tr|A0A0D9SG12|A0A0D9SG12_HUMAN,tr|F6S8Q4|F6S8Q4_HUMAN,tr|A0A2U3TZJ9|A0A2U3TZJ9_HUMAN,tr|A0A2R8Y4A4|A0A2R8Y4A4_HUMAN" 18 2159.9735 0.99 88802 21422 3 2159.978809 720.9984 ATP-dependent RNA helicase DDX3X OS=Homo sapiens OX=9606 GN=DDX3X PE=1 SV=3 5.33 3329.2 - 1.45E+06 - - - 2.4695 - 3.473 0.544 - 530.1 1 2 0 0.0053 17 0 0 0 3.93E+07 3.98E+07 - - - 7.7489 0.9999 221125_WJC_METTL3_EV_vs_WT_F06.21425.21425.3 0.000315 16/60 R.VSLDVNHFAPDELTVK.T "sp|P04792|HSPB1_HUMAN,tr|A0A6Q8PGY2|A0A6Q8PGY2_HUMAN,tr|A0A6Q8PHJ6|A0A6Q8PHJ6_HUMAN,tr|A0A6Q8PHA6|A0A6Q8PHA6_HUMAN,tr|A0A6Q8PF43|A0A6Q8PF43_HUMAN,tr|A0A6Q8PFK8|A0A6Q8PFK8_HUMAN,tr|A0A6Q8PGK1|A0A6Q8PGK1_HUMAN,tr|A0A6Q8PH65|A0A6Q8PH65_HUMAN,tr|A0A6Q8PFE7|A0A6Q8PFE7_HUMAN" 9 1782.9152 3.97 88805 21425 3 1782.918131 595.3123 Heat shock protein beta-1 OS=Homo sapiens OX=9606 GN=HSPB1 PE=1 SV=2 4.54 3329.5 - 892608 - - - 1.6355 - 3.02 0.449 - 332.8 1 2 0 0.0029 16 0 0 0 1.80E+07 4.54E+06 - - - 6.381 1 221125_WJC_METTL3_EV_vs_WT_F06.21426.21426.2 8.40E-13 19/38 K.EQVTNVGGAVVTGVTAVAQK.T "sp|P37840|SYUA_HUMAN,tr|A0A669KB41|A0A669KB41_HUMAN,tr|A0A669KBH5|A0A669KBH5_HUMAN,tr|H6UYS7|H6UYS7_HUMAN,tr|E7EPV7|E7EPV7_HUMAN" 5 1927.0375 1.78 88806 21426 2 1927.039557 964.526 Alpha-synuclein OS=Homo sapiens OX=9606 GN=SNCA PE=1 SV=1 6.1 3329.6 - 591122 - - - 1.0908 - 3.722 0.701 - 882.5 1 2 0 0.0021 20 0 0 0 3.70E+07 2.07E+07 - - - 7.4491 1 221125_WJC_METTL3_EV_vs_WT_F06.21427.21427.4 9.58E-07 14/102 R.SPSELFAQHIVTIVHHVK.E "sp|Q9Y2W1|TR150_HUMAN,tr|A0A3B3ITZ9|A0A3B3ITZ9_HUMAN" 2 2041.1109 2.75 88807 21427 4 2041.112952 511.285 Thyroid hormone receptor-associated protein 3 OS=Homo sapiens OX=9606 GN=THRAP3 PE=1 SV=2 6.78 3329.7 - 346879 - - - 1.0078 - 2.961 0.482 - 140.2 1 2 0 0.0021 18 0 0 0 1.87E+10 6.82E+09 - - - 3.7926 1 221125_WJC_METTL3_EV_vs_WT_F06.21430.21430.4 1.69E-10 30/186 K.VGGTNLGAPGAFGQSPFSQPPAPPHQNTFPPR.S sp|Q96I24|FUBP3_HUMAN 1 3227.5901 2.09 88808 21430 4 3227.595672 807.9048 Far upstream element-binding protein 3 OS=Homo sapiens OX=9606 GN=FUBP3 PE=1 SV=2 9.73 3330.1 - 5.98E+06 - - - 1.7326 - 5.049 0.525 - 252.2 1 2 0 0.0056 32 0 0 0 2.01E+08 9.62E+07 - - - 4.2829 1 221125_WJC_METTL3_EV_vs_WT_F06.21431.21431.4 3.41E-10 20/114 R.GWTLNSAGYLLGPHAVGNHR.S sp|P22466|GALA_HUMAN 1 2119.0712 0.43 88809 21431 4 2119.06786 530.7751 Galanin peptides OS=Homo sapiens OX=9606 GN=GAL PE=1 SV=3 8.76 3330.2 - 1.19E+06 - - - -1.5549 - 4.224 0.589 - 455.7 1 2 0 -0.0033 20 0 0 0 1.17E+07 2.73E+07 - - - 4.8334 0.9999 221125_WJC_METTL3_EV_vs_WT_F06.21432.21432.4 1.96E-06 17/132 K.LQLLEEKTDEDEKTILNLENSNK.S sp|Q8IX12|CCAR1_HUMAN 1 2715.3814 4.68 88810 21432 4 2715.384218 679.8526 Cell division cycle and apoptosis regulator protein 1 OS=Homo sapiens OX=9606 GN=CCAR1 PE=1 SV=2 4.25 3330.3 - 1.33E+06 - - - 1.0249 - 3.577 0.542 - 164.9 1 2 2 0.0028 23 0 0 0 1.84E+08 3.93E+07 - - - 4.3557 1 221125_WJC_METTL3_EV_vs_WT_F06.21433.21433.4 2.44E-09 17/132 K.SWASLFHDSKPSSSSPVAYVETK.Y sp|Q14694|UBP10_HUMAN 1 2509.2125 0.93 88811 21433 4 2509.216251 628.3104 Ubiquitin carboxyl-terminal hydrolase 10 OS=Homo sapiens OX=9606 GN=USP10 PE=1 SV=2 6.47 3330.4 - 523868 - - - 1.4873 - 3.224 0.555 - 157.3 1 2 0 0.0037 23 0 0 0 9.45E+06 1.02E+07 - - - 4.435 1 221125_WJC_METTL3_EV_vs_WT_F06.21436.21436.4 4.18E-06 31/186 K.VGGTNLGAPGAFGQSPFSQPPAPPHQNTFPPR[166.11].S sp|Q96I24|FUBP3_HUMAN 1 3237.5984 2.49 88813 21436 4 3237.600554 810.4069 Far upstream element-binding protein 3 OS=Homo sapiens OX=9606 GN=FUBP3 PE=1 SV=2 9.73 3330.8 - 2.38E+06 - - - 0.6808 - 3.238 0.488 - 343.8 1 2 0 0.0022 32 0 0 0 1.98E+08 7.97E+07 - - - 3.8277 1 221125_WJC_METTL3_EV_vs_WT_F06.21438.21438.3 2.16E-11 20/76 K.EQVTNVGGAVVTGVTAVAQK.T "sp|P37840|SYUA_HUMAN,tr|A0A669KB41|A0A669KB41_HUMAN,tr|A0A669KBH5|A0A669KBH5_HUMAN,tr|H6UYS7|H6UYS7_HUMAN,tr|E7EPV7|E7EPV7_HUMAN" 5 1927.0375 1.83 88814 21438 3 1927.040075 643.3531 Alpha-synuclein OS=Homo sapiens OX=9606 GN=SNCA PE=1 SV=1 6.1 3331.1 - 5.97E+06 - - - 1.3596 - 4.009 0.614 - 633.9 1 2 0 0.0026 20 0 0 0 1.53E+08 8.37E+07 - - - 8.7534 0.9999 221125_WJC_METTL3_EV_vs_WT_F06.21439.21439.3 0.00107 18/52 R.NKLNDLEEALQQAK.E sp|P35908|K22E_HUMAN 1 1612.842 31959.1 88815 21439 3 1612.842808 538.6213 "Keratin, type II cytoskeletal 2 epidermal OS=Homo sapiens OX=9606 GN=KRT2 PE=1 SV=2" 4.68 3331.1 - 2.12E+06 - - - 0.47 - 3.635 0.457 - 595.9 1 2 1 0.0008 14 0 0 0 2.78E+09 8.69E+04 - - - 7.0647 1 221125_WJC_METTL3_EV_vs_WT_F06.21441.21441.2 1.64E-10 19/38 K.EQVTNVGGAVVTGVTAVAQK[136.11].T "sp|P37840|SYUA_HUMAN,tr|A0A669KB41|A0A669KB41_HUMAN,tr|A0A669KBH5|A0A669KBH5_HUMAN,tr|H6UYS7|H6UYS7_HUMAN,tr|E7EPV7|E7EPV7_HUMAN" 5 1935.0517 1.78 88817 21441 2 1935.05127 968.5331 Alpha-synuclein OS=Homo sapiens OX=9606 GN=SNCA PE=1 SV=1 6.1 3331.4 - 836125 - - - -0.199 - 3.954 0.666 - 1021.1 1 2 0 -0.0004 20 0 0 0 3.70E+07 2.07E+07 - - - 7.3398 1 221125_WJC_METTL3_EV_vs_WT_F06.21442.21442.3 3.67E-08 23/48 R.K[136.11]IEEIK[136.11]DFLLTAR[166.11].R "sp|P63173|RL38_HUMAN,tr|J3KT73|J3KT73_HUMAN,tr|J3QL01|J3QL01_HUMAN,tr|J3KSP2|J3KSP2_HUMAN" 4 1600.9399 1.14 88818 21442 3 1600.940627 534.6539 60S ribosomal protein L38 OS=Homo sapiens OX=9606 GN=RPL38 PE=1 SV=2 6.18 3331.5 - 800606 - - - 0.4772 - 3.362 0.64 - 831.8 1 2 1 0.0008 13 0 0 0 9.62E+08 8.44E+08 - - - 8.9627 1 221125_WJC_METTL3_EV_vs_WT_F06.21446.21446.3 3.95E-10 25/48 R.KIEEIKDFLLTAR.R "sp|P63173|RL38_HUMAN,tr|J3KT73|J3KT73_HUMAN,tr|J3QL01|J3QL01_HUMAN,tr|J3KSP2|J3KSP2_HUMAN" 4 1574.9032 1.14 88820 21446 3 1574.90459 525.975 60S ribosomal protein L38 OS=Homo sapiens OX=9606 GN=RPL38 PE=1 SV=2 6.18 3332 - 1.56E+06 - - - 0.8864 - 3.594 0.632 - 982.9 1 2 1 0.0014 13 0 0 0 9.62E+08 8.44E+08 - - - 9.0542 1 221125_WJC_METTL3_EV_vs_WT_F06.21450.21450.3 1.17E-07 28/124 K.VGGTNLGAPGAFGQSPFSQPPAPPHQNTFPPR[166.11].S sp|Q96I24|FUBP3_HUMAN 1 3237.5984 2.39 88824 21450 3 3237.601492 1080.2067 Far upstream element-binding protein 3 OS=Homo sapiens OX=9606 GN=FUBP3 PE=1 SV=2 9.73 3332.5 - 1.22E+06 - - - 0.9705 - 3.974 0.582 - 492.6 1 2 0 0.0031 32 0 0 0 1.50E+08 6.27E+07 - - - 8.2022 1 221125_WJC_METTL3_EV_vs_WT_F06.21451.21451.4 4.32E-10 27/126 R.VSGQGLHEGHTFEPAEFIIDTR.D "sp|P21333|FLNA_HUMAN,tr|Q60FE5|Q60FE5_HUMAN,tr|H0Y5C6|H0Y5C6_HUMAN" 3 2439.1819 0.9 88825 21451 4 2439.187028 610.8027 Filamin-A OS=Homo sapiens OX=9606 GN=FLNA PE=1 SV=4 4.8 3332.6 - 1.19E+06 - - - 2.1073 - 4.088 0.626 - 369.7 1 2 0 0.0051 22 0 0 0 4.79E+07 5.34E+07 - - - 5.134 1 221125_WJC_METTL3_EV_vs_WT_F06.21452.21452.4 1.34E-07 20/126 R.VSGQGLHEGHTFEPAEFIIDTR[166.11].D "sp|P21333|FLNA_HUMAN,tr|Q60FE5|Q60FE5_HUMAN,tr|H0Y5C6|H0Y5C6_HUMAN" 3 2449.1902 0.93 88826 21452 4 2449.195481 613.3048 Filamin-A OS=Homo sapiens OX=9606 GN=FLNA PE=1 SV=4 4.8 3332.7 - 1.07E+06 - - - 2.1734 - 3.924 0.542 - 170.6 1 2 0 0.0053 22 0 0 0 4.79E+07 5.15E+07 - - - 4.3894 0.9998 221125_WJC_METTL3_EV_vs_WT_F06.21453.21453.4 9.94E-06 17/72 R.K[136.11]IEEIK[136.11]DFLLTAR[166.11].R "sp|P63173|RL38_HUMAN,tr|J3KT73|J3KT73_HUMAN,tr|J3QL01|J3QL01_HUMAN,tr|J3KSP2|J3KSP2_HUMAN" 4 1600.9399 1.09 88827 21453 4 1600.942136 401.2422 60S ribosomal protein L38 OS=Homo sapiens OX=9606 GN=RPL38 PE=1 SV=2 6.18 3332.8 - 607231 - - - 1.4198 - 2.852 0.458 - 271.3 1 2 1 0.0023 13 0 0 0 2.03E+08 1.87E+08 - - - 3.6004 0.9894 221125_WJC_METTL3_EV_vs_WT_F06.21455.21455.3 1.93E-06 15/48 L.DGIHLLDPDVVAR[166.11].F sp|Q86U44|MTA70_HUMAN 1 1428.76 0.01 88829 21455 3 1428.760785 477.2606 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 4.41 3333.1 - 430130 - - - 0.5158 - 2.673 0.356 - 426.4 1 1 0 0.0007 13 0 0 0 1.12E+05 1.05E+07 - - - 5.1746 0.9999 221125_WJC_METTL3_EV_vs_WT_F06.21458.21458.4 2.89E-11 22/102 K.WKPPMIDNPSYQGIWKPR.K "sp|P27824|CALX_HUMAN,tr|A0A7P0T937|A0A7P0T937_HUMAN,tr|A0A7P0T840|A0A7P0T840_HUMAN,tr|A0A7P0TB65|A0A7P0TB65_HUMAN,tr|A0A7P0TAE9|A0A7P0TAE9_HUMAN,tr|D6RGY2|D6RGY2_HUMAN,tr|A0A7P0T8G1|A0A7P0T8G1_HUMAN,tr|A0A7P0Z4D6|A0A7P0Z4D6_HUMAN,tr|A0A7P0T9L0|A0A7P0T9L0_HUMAN" 9 2212.1252 1.16 88831 21458 4 2212.131771 554.0386 Calnexin OS=Homo sapiens OX=9606 GN=CANX PE=1 SV=2 9.7 3333.4 - 1.46E+06 - - - 2.9863 - 3.607 0.573 - 469 1 2 0 0.0066 18 0 0 0 4.43E+07 3.83E+07 - - - 4.651 1 221125_WJC_METTL3_EV_vs_WT_F06.21460.21460.3 6.88E-15 30/88 K.LQLLEEKTDEDEKTILNLENSNK.S sp|Q8IX12|CCAR1_HUMAN 1 2715.3814 7.43 88832 21460 3 2715.383007 906.1344 Cell division cycle and apoptosis regulator protein 1 OS=Homo sapiens OX=9606 GN=CCAR1 PE=1 SV=2 4.25 3333.6 - 2.06E+06 - - - 0.5789 - 4.995 0.674 - 685.6 1 2 2 0.0016 23 0 0 0 5.35E+07 7.21E+06 - - - 9.8273 0.9998 221125_WJC_METTL3_EV_vs_WT_F06.21461.21461.4 3.22E-07 15/132 K.LQLLEEK[136.11]TDEDEK[136.11]TILNLENSNK[136.11].S sp|Q8IX12|CCAR1_HUMAN 1 2739.424 4.69 88833 21461 4 2739.425376 685.8633 Cell division cycle and apoptosis regulator protein 1 OS=Homo sapiens OX=9606 GN=CCAR1 PE=1 SV=2 4.25 3333.7 - 1.94E+06 - - - 0.4895 - 2.836 0.467 - 122.2 1 2 2 0.0013 23 0 0 0 1.84E+08 3.93E+07 - - - 3.6281 1 221125_WJC_METTL3_EV_vs_WT_F06.21462.21462.4 5.97E-08 22/114 K.HFSIHPDTGVITTTTPFLDR.E sp|Q08554|DSC1_HUMAN 1 2254.1382 1.24 88834 21462 4 2254.140015 564.5418 Desmocollin-1 OS=Homo sapiens OX=9606 GN=DSC1 PE=1 SV=2 5.98 3333.8 - 1.28E+06 - - - 0.791 - 3.151 0.52 - 378 1 2 0 0.0018 20 0 0 0 1.42E+07 1.14E+07 - - - 4.1353 1 221125_WJC_METTL3_EV_vs_WT_F06.21463.21463.3 3.40E-10 22/84 R.YPDSHQLFVGNLPHDIDENELK.E "sp|Q9UN86|G3BP2_HUMAN,tr|A0A7I2V3E2|A0A7I2V3E2_HUMAN,tr|A0A7I2V647|A0A7I2V647_HUMAN,tr|A0A7I2V3Z6|A0A7I2V3Z6_HUMAN,tr|A0A7I2YQL7|A0A7I2YQL7_HUMAN,tr|A0A7I2YQD9|A0A7I2YQD9_HUMAN,tr|A0A7I2V3P9|A0A7I2V3P9_HUMAN" 7 2579.2292 2.27 88835 21463 3 2579.237351 860.7504 Ras GTPase-activating protein-binding protein 2 OS=Homo sapiens OX=9606 GN=G3BP2 PE=1 SV=2 4.42 3333.9 - 791587 - - - 3.1478 - 4.408 0.567 - 436.4 1 2 0 0.0081 22 0 0 0 2.28E+07 1.01E+07 - - - 8.3762 1 221125_WJC_METTL3_EV_vs_WT_F06.21467.21467.3 7.06E-18 30/108 K.LSFDSSPTSSTDGHSSYGLDSGFC[160.03]TISR.L sp|Q00587|BORG5_HUMAN 1 2967.2829 1.34 88837 21467 3 2967.282458 990.1016 Cdc42 effector protein 1 OS=Homo sapiens OX=9606 GN=CDC42EP1 PE=1 SV=1 4.41 3334.5 - 1.50E+06 - - - -0.1355 - 4.982 0.718 - 813.4 1 2 0 -0.0004 28 0 0 0 3.55E+07 2.65E+07 - - - 10.2393 1 221125_WJC_METTL3_EV_vs_WT_F06.21468.21468.2 4.78E-09 18/24 R.K[136.11]IEEIK[136.11]DFLLTAR[166.11].R "sp|P63173|RL38_HUMAN,tr|J3KT73|J3KT73_HUMAN,tr|J3QL01|J3QL01_HUMAN,tr|J3KSP2|J3KSP2_HUMAN" 4 1600.9399 1.11 88838 21468 2 1600.938666 801.4772 60S ribosomal protein L38 OS=Homo sapiens OX=9606 GN=RPL38 PE=1 SV=2 6.18 3334.6 - 844629 - - - -0.7477 - 3.548 0.627 - 1113.1 1 2 1 -0.0012 13 0 0 0 5.97E+07 5.36E+07 - - - 6.9219 0.9999 221125_WJC_METTL3_EV_vs_WT_F06.21469.21469.4 0.00011 17/72 R.KIEEIKDFLLTAR.R "sp|P63173|RL38_HUMAN,tr|J3KT73|J3KT73_HUMAN,tr|J3QL01|J3QL01_HUMAN,tr|J3KSP2|J3KSP2_HUMAN" 4 1574.9032 1.09 88839 21469 4 1574.903349 394.7331 60S ribosomal protein L38 OS=Homo sapiens OX=9606 GN=RPL38 PE=1 SV=2 6.18 3334.7 - 2.35E+06 - - - 0.0984 - 2.953 0.505 - 278.2 1 2 1 0.0002 13 0 0 0 2.03E+08 1.87E+08 - - - 4.023 1 221125_WJC_METTL3_EV_vs_WT_F06.21470.21470.3 9.17E-17 29/108 K.LSFDSSPTSSTDGHSSYGLDSGFC[160.03]TISR[166.11].L sp|Q00587|BORG5_HUMAN 1 2977.2911 1.34 88840 21470 3 2977.285419 993.4377 Cdc42 effector protein 1 OS=Homo sapiens OX=9606 GN=CDC42EP1 PE=1 SV=1 4.41 3334.8 - 1.35E+06 - - - -1.9182 - 5.007 0.746 - 791.3 1 2 0 -0.0057 28 0 0 0 3.55E+07 2.65E+07 - - - 10.5615 0.9999 221125_WJC_METTL3_EV_vs_WT_F06.21471.21471.3 3.87E-09 16/64 K.HQLEIFDALGSQAC[160.03]SNK.N "sp|Q9UPN3|MACF1_HUMAN,tr|H3BQK9|H3BQK9_HUMAN,tr|A0A7P0MQR8|A0A7P0MQR8_HUMAN,tr|H0Y390|H0Y390_HUMAN,tr|H3BPE1|H3BPE1_HUMAN,tr|A0A669KB06|A0A669KB06_HUMAN,tr|A0A590UJG2|A0A590UJG2_HUMAN" 7 1916.9051 4.37 88841 21471 3 1916.912157 639.9756 "Microtubule-actin cross-linking factor 1, isoforms 1\2\3\5 OS=Homo sapiens OX=9606 GN=MACF1 PE=1 SV=4" 5.32 3334.9 - 633606 - - - 3.7018 - 2.832 0.565 - 335.6 1 2 0 0.0071 17 0 0 0 8.29E+06 1.90E+06 - - - 7.4671 0.9997 221125_WJC_METTL3_EV_vs_WT_F06.21475.21475.4 1.12E-05 22/168 K.YLSQLAEEGLKETEGADSPRPEDSGIVPR.F sp|Q5T481|RBM20_HUMAN 1 3142.5419 1 88843 21475 4 3142.542853 786.6427 RNA-binding protein 20 OS=Homo sapiens OX=9606 GN=RBM20 PE=1 SV=3 4.25 3335.5 - 1.47E+06 - - - 0.3185 - 2.957 0.446 - 105.5 1 2 1 0.001 29 0 0 0 1.40E+07 1.39E+07 - - - 3.4418 1 221125_WJC_METTL3_EV_vs_WT_F06.21480.21480.4 4.86E-09 21/102 R.SPSELFAQHIVTIVHHVK[136.11].E "sp|Q9Y2W1|TR150_HUMAN,tr|A0A3B3ITZ9|A0A3B3ITZ9_HUMAN" 2 2049.1251 2.75 88848 21480 4 2049.125104 513.2886 Thyroid hormone receptor-associated protein 3 OS=Homo sapiens OX=9606 GN=THRAP3 PE=1 SV=2 6.78 3336.1 - 1.03E+06 - - - 0.0044 - 3.442 0.567 - 386.3 1 2 0 0 18 0 0 0 1.87E+10 6.82E+09 - - - 4.5846 0.9998 221125_WJC_METTL3_EV_vs_WT_F06.21489.21489.4 0.00389 17/126 R.YPDSHQLFVGNLPHDIDENELK.E "sp|Q9UN86|G3BP2_HUMAN,tr|A0A7I2V3E2|A0A7I2V3E2_HUMAN,tr|A0A7I2V647|A0A7I2V647_HUMAN,tr|A0A7I2V3Z6|A0A7I2V3Z6_HUMAN,tr|A0A7I2YQL7|A0A7I2YQL7_HUMAN,tr|A0A7I2YQD9|A0A7I2YQD9_HUMAN,tr|A0A7I2V3P9|A0A7I2V3P9_HUMAN" 7 2579.2292 1.6 88855 21489 4 2579.229614 645.8146 Ras GTPase-activating protein-binding protein 2 OS=Homo sapiens OX=9606 GN=G3BP2 PE=1 SV=2 4.42 3337.3 - 4.22E+06 - - - 0.1481 - 2.787 0.379 - 153.1 1 2 0 0.0004 22 0 0 0 1.31E+08 8.17E+07 - - - 2.8601 1 221125_WJC_METTL3_EV_vs_WT_F06.21491.21491.2 2.38E-06 18/24 R.KIEEIKDFLLTAR.R "sp|P63173|RL38_HUMAN,tr|J3KT73|J3KT73_HUMAN,tr|J3QL01|J3QL01_HUMAN,tr|J3KSP2|J3KSP2_HUMAN" 4 1574.9032 1.11 88857 21491 2 1574.908251 788.4589 60S ribosomal protein L38 OS=Homo sapiens OX=9606 GN=RPL38 PE=1 SV=2 6.18 3337.5 - 1.33E+06 - - - 3.211 - 3.419 0.593 - 773.8 1 2 1 0.0051 13 0 0 0 5.97E+07 5.36E+07 - - - 6.5745 1 221125_WJC_METTL3_EV_vs_WT_F06.21492.21492.3 1.26E-06 23/64 K.MLQAPESVLAEHYQDLR.R "sp|O00746|NDKM_HUMAN,tr|Q4TT34|Q4TT34_HUMAN,tr|H0Y6J0|H0Y6J0_HUMAN,tr|F2Z2X0|F2Z2X0_HUMAN,tr|A2IDC9|A2IDC9_HUMAN" 5 1998.9833 2.28 88858 21492 3 1998.984043 667.335 "Nucleoside diphosphate kinase, mitochondrial OS=Homo sapiens OX=9606 GN=NME4 PE=1 SV=1" 4.65 3337.6 - 1.01E+06 - - - 0.3662 - 4.274 0.584 - 711.2 1 2 0 0.0007 17 0 0 0 2.67E+07 1.17E+07 - - - 8.7204 0.9998 221125_WJC_METTL3_EV_vs_WT_F06.21495.21495.3 4.03E-07 14/84 R.YPDSHQLFVGNLPHDIDENELK[136.11].E "sp|Q9UN86|G3BP2_HUMAN,tr|A0A7I2V3E2|A0A7I2V3E2_HUMAN,tr|A0A7I2V647|A0A7I2V647_HUMAN,tr|A0A7I2V3Z6|A0A7I2V3Z6_HUMAN,tr|A0A7I2YQL7|A0A7I2YQL7_HUMAN,tr|A0A7I2YQD9|A0A7I2YQD9_HUMAN,tr|A0A7I2V3P9|A0A7I2V3P9_HUMAN" 7 2587.2434 2.46 88861 21495 3 2587.254893 863.4218 Ras GTPase-activating protein-binding protein 2 OS=Homo sapiens OX=9606 GN=G3BP2 PE=1 SV=2 4.42 3338 - 479262 - - - 4.4298 - 2.951 0.534 - 168.5 1 2 0 0.0115 22 0 0 0 2.17E+07 8.82E+06 - - - 7.056 0.9998 221125_WJC_METTL3_EV_vs_WT_F06.21499.21499.3 9.81E-05 17/48 R.K[136.11]IEEIKDFLLTAR[166.11].R "sp|P63173|RL38_HUMAN,tr|J3KT73|J3KT73_HUMAN,tr|J3QL01|J3QL01_HUMAN,tr|J3KSP2|J3KSP2_HUMAN" 4 1592.9257 - 88863 21499 3 1592.928301 531.9825 60S ribosomal protein L38 OS=Homo sapiens OX=9606 GN=RPL38 PE=1 SV=2 6.18 3338.6 - 719110 - - - 1.6561 - 2.746 0.486 - 415.4 1 2 1 0.0026 13 0 0 0 - - - - - 6.6965 0.9971 221125_WJC_METTL3_EV_vs_WT_F06.21501.21501.3 2.70E-07 15/76 A.LSSASTSSHNLQSIFNIGSR[166.11].G "sp|P43243|MATR3_HUMAN,tr|A8MXP9|A8MXP9_HUMAN,tr|D6R991|D6R991_HUMAN,tr|D6REK4|D6REK4_HUMAN,tr|A0A0R4J2E8|A0A0R4J2E8_HUMAN,tr|D6RCM3|D6RCM3_HUMAN,tr|D6R8Z5|D6R8Z5_HUMAN,tr|D6REM6|D6REM6_HUMAN" 8 2115.0584 1.35 88865 21501 3 2115.0542 706.0267 Matrin-3 OS=Homo sapiens OX=9606 GN=MATR3 PE=1 SV=2 9.76 3338.8 - 806945 - - - -1.9929 - 3.481 0.527 - 284.9 1 1 0 -0.0042 20 0 0 0 7.93E+07 5.87E+07 - - - 7.4404 0.9997 221125_WJC_METTL3_EV_vs_WT_F06.21502.21502.4 3.71E-06 19/102 K.LR[166.11]EGEITHLQLEIGNLEK[136.11].T "sp|P82094|TMF1_HUMAN,tr|A0A2R8Y7M0|A0A2R8Y7M0_HUMAN" 2 2109.1549 1.5 88866 21502 4 2109.157722 528.296 TATA element modulatory factor OS=Homo sapiens OX=9606 GN=TMF1 PE=1 SV=2 4.91 3338.9 - 658043 - - - 1.3437 - 3.714 0.433 - 300.9 1 2 1 0.0028 18 0 0 0 1.41E+07 9.43E+06 - - - 3.4435 1 221125_WJC_METTL3_EV_vs_WT_F06.21505.21505.3 4.29E-15 22/68 R.QQQFNVQALVAVGDHASK[136.11].Q "sp|P14868|SYDC_HUMAN,tr|C9JQM9|C9JQM9_HUMAN,tr|C9J7S3|C9J7S3_HUMAN,tr|H7C278|H7C278_HUMAN,tr|C9JLC1|C9JLC1_HUMAN" 5 1947.0054 0.79 88867 21505 3 1947.002762 650.0091 "Aspartate--tRNA ligase, cytoplasmic OS=Homo sapiens OX=9606 GN=DARS1 PE=1 SV=2" 6.74 3339.3 - 1.69E+06 - - - -1.3415 - 4.395 0.655 - 716.2 1 2 0 -0.0026 18 0 0 0 4.78E+07 6.08E+07 - - - 9.5284 1 221125_WJC_METTL3_EV_vs_WT_F06.21507.21507.2 1.39E-09 19/26 R.NKLNDLEEALQQAK.E sp|P35908|K22E_HUMAN 1 1612.842 999 88869 21507 2 1612.841091 807.4283 "Keratin, type II cytoskeletal 2 epidermal OS=Homo sapiens OX=9606 GN=KRT2 PE=1 SV=2" 4.68 3339.4 - 3.15E+07 - - - -0.5946 - 3.9 0.67 - 1408.8 1 2 1 -0.001 14 0 0 0 5.39E+08 0.00E+00 - - - 7.4046 0.9999 221125_WJC_METTL3_EV_vs_WT_F06.21508.21508.3 0.00206 22/68 K.LREGEITHLQLEIGNLEK.T "sp|P82094|TMF1_HUMAN,tr|A0A2R8Y7M0|A0A2R8Y7M0_HUMAN" 2 2091.1324 0.96 88870 21508 3 2091.133759 698.0514 TATA element modulatory factor OS=Homo sapiens OX=9606 GN=TMF1 PE=1 SV=2 4.91 3339.6 - 1.73E+06 - - - 0.6413 - 4.257 0.491 - 487.5 1 2 1 0.0013 18 0 0 0 1.39E+07 1.45E+07 - - - 7.6209 1 221125_WJC_METTL3_EV_vs_WT_F06.21513.21513.3 6.63E-12 23/72 K.GLEEITVHNKDEVYQILEK.G "sp|P52732|KIF11_HUMAN,tr|A0A7I2YQY4|A0A7I2YQY4_HUMAN,tr|A0A7I2V3A9|A0A7I2V3A9_HUMAN,tr|A0A7I2V3V3|A0A7I2V3V3_HUMAN" 4 2256.1638 4.88 88873 21513 3 2256.16328 753.0619 Kinesin-like protein KIF11 OS=Homo sapiens OX=9606 GN=KIF11 PE=1 SV=2 4.57 3340.2 - 2.67E+06 - - - -0.2207 - 4.768 0.579 - 704 1 2 1 -0.0005 19 0 0 0 4.24E+08 8.69E+07 - - - 8.8325 0.9998 221125_WJC_METTL3_EV_vs_WT_F06.21515.21515.3 1.49E-11 20/68 R.SPSELFAQHIVTIVHHVK.E "sp|Q9Y2W1|TR150_HUMAN,tr|A0A3B3ITZ9|A0A3B3ITZ9_HUMAN" 2 2041.1109 2.61 88875 21515 3 2041.121583 681.3776 Thyroid hormone receptor-associated protein 3 OS=Homo sapiens OX=9606 GN=THRAP3 PE=1 SV=2 6.78 3340.4 - 1.78E+06 - - - 5.2364 - 4.054 0.57 - 456.3 1 2 0 0.0107 18 0 0 0 3.77E+09 1.45E+09 - - - 8.3774 1 221125_WJC_METTL3_EV_vs_WT_F06.21519.21519.4 2.59E-06 20/120 K.RTELFIAAEGIHTGQFVYC[160.03]GK.K "sp|P62917|RL8_HUMAN,tr|G3V1A1|G3V1A1_HUMAN,tr|E9PKZ0|E9PKZ0_HUMAN,tr|E9PKU4|E9PKU4_HUMAN" 4 2396.1947 0.73 88879 21519 4 2396.194437 600.056 60S ribosomal protein L8 OS=Homo sapiens OX=9606 GN=RPL8 PE=1 SV=2 6.75 3340.9 - 308852 - - - -0.1102 - 3.544 0.506 - 292 1 2 0 -0.0003 21 0 0 0 2.79E+06 3.82E+06 - - - 4.0485 0.8916 221125_WJC_METTL3_EV_vs_WT_F06.21521.21521.3 0.000203 12/100 K.NGFSSVQATQLQTTQSVEGATGSAVK.S "sp|Q14157|UBP2L_HUMAN,tr|F8W726|F8W726_HUMAN" 2 2595.2776 1.22 88880 21521 3 2596.26328 866.0998 Ubiquitin-associated protein 2-like OS=Homo sapiens OX=9606 GN=UBAP2L PE=1 SV=2 6 3341.2 - 989930 - - - 379.7825 - 2.645 0.447 - 98.3 1 2 0 0.9856 26 0 0 0 3.09E+06 2.53E+06 - - - 5.4883 0.999 221125_WJC_METTL3_EV_vs_WT_F06.21523.21523.3 5.92E-09 22/76 A.LSSASTSSHNLQSIFNIGSR.G "sp|P43243|MATR3_HUMAN,tr|A8MXP9|A8MXP9_HUMAN,tr|D6R991|D6R991_HUMAN,tr|D6REK4|D6REK4_HUMAN,tr|A0A0R4J2E8|A0A0R4J2E8_HUMAN,tr|D6RCM3|D6RCM3_HUMAN,tr|D6R8Z5|D6R8Z5_HUMAN,tr|D6REM6|D6REM6_HUMAN" 8 2105.0501 1.35 88881 21523 3 2105.04996 702.6907 Matrin-3 OS=Homo sapiens OX=9606 GN=MATR3 PE=1 SV=2 9.76 3341.4 - 2.82E+06 - - - -0.0879 - 3.594 0.599 - 624.7 1 1 0 -0.0002 20 0 0 0 7.93E+07 5.87E+07 - - - 8.3217 0.9999 221125_WJC_METTL3_EV_vs_WT_F06.21530.21530.4 2.25E-07 15/108 K.GLEEITVHNK[136.11]DEVYQILEK[136.11].G "sp|P52732|KIF11_HUMAN,tr|A0A7I2YQY4|A0A7I2YQY4_HUMAN,tr|A0A7I2V3A9|A0A7I2V3A9_HUMAN,tr|A0A7I2V3V3|A0A7I2V3V3_HUMAN" 4 2272.1922 4.58 88886 21530 4 2272.19271 569.0553 Kinesin-like protein KIF11 OS=Homo sapiens OX=9606 GN=KIF11 PE=1 SV=2 4.57 3342.2 - 3.30E+06 - - - 0.2341 - 3.312 0.555 - 197.5 1 2 1 0.0005 19 0 0 0 4.29E+08 9.37E+07 - - - 4.4617 1 221125_WJC_METTL3_EV_vs_WT_F06.21543.21543.4 2.37E-08 24/126 R.NLVQC[160.03]GDFPHLLVYGPSGAGK[136.11]K[136.11].T sp|P40938|RFC3_HUMAN 1 2372.2282 0.55 88895 21543 4 2372.227996 594.0643 Replication factor C subunit 3 OS=Homo sapiens OX=9606 GN=RFC3 PE=1 SV=2 8.18 3343.7 - 1.11E+06 - - - -0.0805 - 3.917 0.647 - 357.8 1 2 0 -0.0002 22 0 0 0 1.26E+07 2.28E+07 - - - 5.3042 1 221125_WJC_METTL3_EV_vs_WT_F06.21544.21544.3 2.61E-13 24/68 R.SPSELFAQHIVTIVHHVK[136.11].E "sp|Q9Y2W1|TR150_HUMAN,tr|A0A3B3ITZ9|A0A3B3ITZ9_HUMAN" 2 2049.1251 2.61 88896 21544 3 2049.125032 684.049 Thyroid hormone receptor-associated protein 3 OS=Homo sapiens OX=9606 GN=THRAP3 PE=1 SV=2 6.78 3343.9 - 1.64E+06 - - - -0.0307 - 4.408 0.685 - 988.4 1 2 0 -0.0001 18 0 0 0 3.77E+09 1.44E+09 - - - 9.8709 1 221125_WJC_METTL3_EV_vs_WT_F06.21546.21546.4 3.84E-08 22/108 R.DQFLDTLQAHGHDVNSFVR[166.11].S "sp|Q15021|CND1_HUMAN,tr|E7EN77|E7EN77_HUMAN" 2 2208.0588 0.67 88898 21546 4 2208.062668 553.022 Condensin complex subunit 1 OS=Homo sapiens OX=9606 GN=NCAPD2 PE=1 SV=3 5.13 3344.1 - 1.11E+06 - - - 1.7744 - 4.166 0.537 - 480.2 1 2 0 0.0039 19 0 0 0 8.44E+06 1.26E+07 - - - 4.3817 1 221125_WJC_METTL3_EV_vs_WT_F06.21548.21548.4 3.16E-09 28/162 R.ASLPQAATFGELSGPLKPGSPYRPPVPR.A "sp|Q14687|GSE1_HUMAN,tr|H0Y613|H0Y613_HUMAN" 2 2889.5501 4.19 88900 21548 4 2889.543596 723.3948 Genetic suppressor element 1 OS=Homo sapiens OX=9606 GN=GSE1 PE=1 SV=3 9.99 3344.4 - 777378 - - - -2.2554 - 3.781 0.593 - 482.3 1 2 0 -0.0065 28 0 0 0 2.20E+07 5.26E+06 - - - 4.7986 0.9992 221125_WJC_METTL3_EV_vs_WT_F06.21551.21551.4 1.26E-05 17/114 K.VEESSWLIEDGKVVTVHLEK.L sp|Q9Y266|NUDC_HUMAN 1 2296.1951 1.33 88901 21551 4 2296.203466 575.056 Nuclear migration protein nudC OS=Homo sapiens OX=9606 GN=NUDC PE=1 SV=1 4.57 3344.8 - 1.89E+06 - - - 3.653 - 3.629 0.478 - 196.3 1 2 1 0.0084 20 0 0 0 4.40E+07 3.32E+07 - - - 3.8151 1 221125_WJC_METTL3_EV_vs_WT_F06.21557.21557.4 1.01E-07 18/108 R.DQFLDTLQAHGHDVNSFVR.S "sp|Q15021|CND1_HUMAN,tr|E7EN77|E7EN77_HUMAN" 2 2198.0505 0.67 88907 21557 4 2198.047523 550.5199 Condensin complex subunit 1 OS=Homo sapiens OX=9606 GN=NCAPD2 PE=1 SV=3 5.13 3345.6 - 674006 - - - -1.3453 - 3.53 0.53 - 238.7 1 2 0 -0.003 19 0 0 0 8.44E+06 1.26E+07 - - - 4.265 0.9957 221125_WJC_METTL3_EV_vs_WT_F06.21558.21558.3 3.66E-05 16/44 F.AQHIVTIVHHVK.E "sp|Q9Y2W1|TR150_HUMAN,tr|A0A3B3ITZ9|A0A3B3ITZ9_HUMAN" 2 1380.799 2.5 88908 21558 3 1380.801503 461.2736 Thyroid hormone receptor-associated protein 3 OS=Homo sapiens OX=9606 GN=THRAP3 PE=1 SV=2 8.81 3345.7 - 594170 - - - 1.8105 - 2.78 0.489 - 338.9 1 1 0 0.0025 12 0 0 0 5.19E+08 2.08E+08 - - - 6.8253 1 221125_WJC_METTL3_EV_vs_WT_F06.21562.21562.3 7.33E-18 26/128 R.LFGEAGPASGVGSSGGGGSGSGTGGGDAALDFK.L "sp|Q8IWZ3|ANKH1_HUMAN,tr|E9PDP5|E9PDP5_HUMAN,tr|D6RHC4|D6RHC4_HUMAN" 3 2783.2634 1.25 88910 21562 3 2783.260548 928.7618 Ankyrin repeat and KH domain-containing protein 1 OS=Homo sapiens OX=9606 GN=ANKHD1 PE=1 SV=1 4.03 3346.2 - 1.09E+06 - - - -1.0409 - 5.171 0.726 - 544.5 1 2 0 -0.0029 33 0 0 0 4.99E+07 3.98E+07 - - - 10.4135 1 221125_WJC_METTL3_EV_vs_WT_F06.21566.21566.3 8.27E-08 16/64 K.K[136.11]TESAVSQMQSVIELGR[166.11].V "sp|P41252|SYIC_HUMAN,tr|A0A804HL54|A0A804HL54_HUMAN,tr|A0A804HIV9|A0A804HIV9_HUMAN,tr|A0A804HJN6|A0A804HJN6_HUMAN,tr|A0A804HHW9|A0A804HHW9_HUMAN,tr|A0A0A0MSX9|A0A0A0MSX9_HUMAN,tr|J3KR24|J3KR24_HUMAN,tr|A0A804HJ36|A0A804HJ36_HUMAN" 8 1879.9792 0.62 88912 21566 3 1879.974457 627.667 "Isoleucine--tRNA ligase, cytoplasmic OS=Homo sapiens OX=9606 GN=IARS1 PE=1 SV=2" 6.14 3346.7 - 875904 - - - -2.5399 - 3.308 0.548 - 370.1 1 2 0 -0.0048 17 0 0 0 1.11E+07 1.80E+07 - - - 7.6707 0.9452 221125_WJC_METTL3_EV_vs_WT_F06.21569.21569.3 4.10E-05 11/100 K.NGFSSVQATQLQTTQSVEGATGSAVK[136.11].S "sp|Q14157|UBP2L_HUMAN,tr|F8W726|F8W726_HUMAN" 2 2603.2918 -1 88915 21569 3 2604.283472 868.7712 Ubiquitin-associated protein 2-like OS=Homo sapiens OX=9606 GN=UBAP2L PE=1 SV=2 6 3347.1 - 462167 - - - 380.915 - 2.193 0.412 - 97.1 1 2 0 0.9916 26 0 0 0 0.00E+00 0.00E+00 - - - 4.6653 0.9985 221125_WJC_METTL3_EV_vs_WT_F06.21570.21570.3 1.92E-06 16/44 F.AQHIVTIVHHVK[136.11].E "sp|Q9Y2W1|TR150_HUMAN,tr|A0A3B3ITZ9|A0A3B3ITZ9_HUMAN" 2 1388.8132 2.5 88916 21570 3 1388.813637 463.945 Thyroid hormone receptor-associated protein 3 OS=Homo sapiens OX=9606 GN=THRAP3 PE=1 SV=2 8.81 3347.2 - 292007 - - - 0.3125 - 2.812 0.557 - 302.8 1 1 0 0.0004 12 0 0 0 5.19E+08 2.08E+08 - - - 7.6157 0.9849 221125_WJC_METTL3_EV_vs_WT_F06.21574.21574.3 2.80E-07 14/60 R.K[136.11]GDMDELEK[136.11]EMLSVEK[136.11].A "sp|Q14683|SMC1A_HUMAN,tr|G8JLG1|G8JLG1_HUMAN" 2 1903.9333 1.3 88918 21574 3 1904.94317 635.6517 Structural maintenance of chromosomes protein 1A OS=Homo sapiens OX=9606 GN=SMC1A PE=1 SV=2 4.36 3347.8 - 304586 - - - 530.4041 - 2.91 0.53 - 166 1 2 1 1.0099 16 0 0 0 3.63E+06 2.80E+06 - - - 6.91 1 221125_WJC_METTL3_EV_vs_WT_F06.21575.21575.4 4.20E-12 24/174 R.STGLILDSGATHTTAIPVHDGYVLQQGIVK[136.11].S sp|O96019|ACL6A_HUMAN 1 3098.6492 0.66 88919 21575 4 3098.651827 775.6696 Actin-like protein 6A OS=Homo sapiens OX=9606 GN=ACTL6A PE=1 SV=1 5.93 3347.8 - 2.63E+06 - - - 0.8591 - 4.316 0.642 - 294.5 1 2 0 0.0027 30 0 0 0 2.20E+07 3.32E+07 - - - 5.2607 0.9999 221125_WJC_METTL3_EV_vs_WT_F06.21576.21576.4 5.19E-05 18/114 K.VEESSWLIEDGK[136.11]VVTVHLEK[136.11].L sp|Q9Y266|NUDC_HUMAN 1 2312.2235 1.32 88920 21576 4 2312.226454 579.0631 Nuclear migration protein nudC OS=Homo sapiens OX=9606 GN=NUDC PE=1 SV=1 4.57 3347.9 - 2.27E+06 - - - 1.2871 - 3.837 0.519 - 247.8 1 2 1 0.003 20 0 0 0 4.42E+07 3.35E+07 - - - 4.1921 0.9998 221125_WJC_METTL3_EV_vs_WT_F06.21577.21577.4 2.29E-05 19/126 R.NLVQC[160.03]GDFPHLLVYGPSGAGKK.T sp|P40938|RFC3_HUMAN 1 2356.1998 0.54 88921 21577 4 2356.190722 590.0572 Replication factor C subunit 3 OS=Homo sapiens OX=9606 GN=RFC3 PE=1 SV=2 8.18 3348 - 1.70E+06 - - - -3.8473 - 3.194 0.501 - 194.2 1 2 0 -0.0091 22 0 0 0 1.15E+07 2.14E+07 - - - 3.9642 1 221125_WJC_METTL3_EV_vs_WT_F06.21581.21581.3 4.53E-09 17/72 K.K[136.11]EDGTFYEFGEDIPEAPER[166.11].L sp|O43776|SYNC_HUMAN 1 2246.0134 1.75 88925 21581 3 2246.01751 749.6784 "Asparagine--tRNA ligase, cytoplasmic OS=Homo sapiens OX=9606 GN=NARS1 PE=1 SV=1" 4 3348.5 - 407490 - - - 1.817 - 3.133 0.574 - 227.8 1 2 0 0.0041 19 0 0 0 5.19E+07 2.97E+07 - - - 7.744 1 221125_WJC_METTL3_EV_vs_WT_F06.21583.21583.3 3.96E-08 22/64 R.HFIMQVVC[160.03]EATQC[160.03]PDTR.V "sp|Q14974|IMB1_HUMAN,tr|J3KTM9|J3KTM9_HUMAN" 2 2090.9336 0.98 88926 21583 3 2090.935778 697.9851 Importin subunit beta-1 OS=Homo sapiens OX=9606 GN=KPNB1 PE=1 SV=2 5.32 3348.7 - 2.83E+06 - - - 1.0412 - 3.7 0.633 - 697.4 1 2 0 0.0022 17 0 0 0 7.81E+07 8.01E+07 - - - 8.902 1 221125_WJC_METTL3_EV_vs_WT_F06.21585.21585.3 8.42E-09 24/64 R.HFIMQVVC[160.03]EATQC[160.03]PDTR[166.11].V "sp|Q14974|IMB1_HUMAN,tr|J3KTM9|J3KTM9_HUMAN" 2 2100.9419 0.98 88927 21585 3 2100.941211 701.3212 Importin subunit beta-1 OS=Homo sapiens OX=9606 GN=KPNB1 PE=1 SV=2 5.32 3348.9 - 2.23E+06 - - - -0.3141 - 4.197 0.684 - 961 1 2 0 -0.0007 17 0 0 0 7.81E+07 7.96E+07 - - - 9.7894 0.9502 221125_WJC_METTL3_EV_vs_WT_F06.21588.21588.3 5.78E-05 18/88 K.EIETYHNLLEGGQEDFESSGAGK.L "sp|P35527|K1C9_HUMAN,tr|K7EQQ3|K7EQQ3_HUMAN" 2 2509.1245 999 88929 21588 3 2510.107592 837.3821 "Keratin, type I cytoskeletal 9 OS=Homo sapiens OX=9606 GN=KRT9 PE=1 SV=3" 4.14 3349.2 - 1.63E+06 - - - 391.81 - 3.431 0.558 - 382.3 1 2 0 0.9831 23 0 0 0 4.17E+06 0.00E+00 - - - 7.381 1 221125_WJC_METTL3_EV_vs_WT_F06.21589.21589.4 1.99E-09 20/174 R.STGLILDSGATHTTAIPVHDGYVLQQGIVK.S sp|O96019|ACL6A_HUMAN 1 3090.635 0.73 88930 21589 4 3090.641476 773.666 Actin-like protein 6A OS=Homo sapiens OX=9606 GN=ACTL6A PE=1 SV=1 5.93 3349.3 - 4.28E+06 - - - 2.1067 - 4.391 0.661 - 188.7 1 2 0 0.0065 30 0 0 0 2.20E+07 3.02E+07 - - - 5.4303 1 221125_WJC_METTL3_EV_vs_WT_F06.21591.21591.3 2.04E-06 17/72 R.R[166.11]GTGQSDDSDIWDDTALIK[136.11].A "sp|Q16637|SMN_HUMAN,tr|E7EQZ4|E7EQZ4_HUMAN,tr|B4DP61|B4DP61_HUMAN,tr|A0A1W2PRV5|A0A1W2PRV5_HUMAN" 4 2109.9934 0.34 88932 21591 3 2109.991601 704.3384 Survival motor neuron protein OS=Homo sapiens OX=9606 GN=SMN1 PE=1 SV=1 3.97 3349.5 - 746206 - - - -0.8346 - 3.369 0.59 - 267.6 1 2 0 -0.0018 19 0 0 0 5.32E+06 1.58E+07 - - - 8.1015 1 221125_WJC_METTL3_EV_vs_WT_F06.21594.21594.4 8.60E-09 27/162 K.GPHLVQSDGTVPFWAHAGNAIPSSDQIR.V sp|P49257|LMAN1_HUMAN 1 2956.458 1.2 88933 21594 4 2956.45637 740.1218 Protein ERGIC-53 OS=Homo sapiens OX=9606 GN=LMAN1 PE=1 SV=2 5.98 3349.9 - 1.22E+06 - - - -0.5524 - 4.422 0.615 - 225.5 1 2 0 -0.0016 28 0 0 0 2.35E+07 1.95E+07 - - - 5.0401 0.9929 221125_WJC_METTL3_EV_vs_WT_F06.21598.21598.3 0.0841 22/76 A.NEDKDPAFTALLTTQTQVQR.E "sp|P54108|CRIS3_HUMAN,tr|J3KPA1|J3KPA1_HUMAN,tr|I3L0A1|I3L0A1_HUMAN" 3 2275.1444 8.89 88937 21598 3 2275.140942 759.3888 Cysteine-rich secretory protein 3 OS=Homo sapiens OX=9606 GN=CRISP3 PE=1 SV=1 4.56 3350.4 - 995093 - - - -1.5375 - 4.342 0.535 - 667.9 1 1 1 -0.0035 20 0 0 0 1.87E+07 2.10E+06 - - - 8.066 0.9923 221125_WJC_METTL3_EV_vs_WT_F06.21600.21600.4 1.91E-06 Dec-72 L.FAQHIVTIVHHVK.E "sp|Q9Y2W1|TR150_HUMAN,tr|A0A3B3ITZ9|A0A3B3ITZ9_HUMAN" 2 1527.8674 2.32 88939 21600 4 1527.864825 382.9741 Thyroid hormone receptor-associated protein 3 OS=Homo sapiens OX=9606 GN=THRAP3 PE=1 SV=2 8.77 3350.6 - 435726 - - - -1.6965 - 1.973 0.472 - 79.3 1 1 0 -0.0026 13 0 0 0 6.79E+07 2.92E+07 - - - 3.5855 0.982 221125_WJC_METTL3_EV_vs_WT_F06.21602.21602.3 2.87E-11 18/92 K.KAFSAVDTDGNGTINAQELGAALK.A sp|Q9NZT1|CALL5_HUMAN 1 2390.2078 -1 88940 21602 3 2391.195519 797.7432 Calmodulin-like protein 5 OS=Homo sapiens OX=9606 GN=CALML5 PE=1 SV=2 4.56 3350.8 - 1.65E+06 - - - 413.249 - 3.877 0.562 - 376.4 1 2 0 0.9878 24 0 0 0 0.00E+00 0.00E+00 - - - 7.6794 1 221125_WJC_METTL3_EV_vs_WT_F06.21604.21604.4 2.21E-07 18/120 K.DGNVLLHEMQIQHPTASLIAK[136.11].V sp|P40227|TCPZ_HUMAN 1 2322.2246 0.6 88941 21604 4 2322.225001 581.5634 T-complex protein 1 subunit zeta OS=Homo sapiens OX=9606 GN=CCT6A PE=1 SV=3 5.99 3351.1 - 7.65E+06 - - - 0.1938 - 3.032 0.543 - 196.4 1 2 0 0.0004 21 0 0 0 6.16E+07 1.03E+08 - - - 4.3189 1 221125_WJC_METTL3_EV_vs_WT_F06.21607.21607.3 5.13E-08 22/68 R.QEQVTAAVAHAVEQQMQK.L "sp|Q8IWX8|CHERP_HUMAN,tr|J3QK89|J3QK89_HUMAN" 2 1994.9844 1.05 88944 21607 3 1994.99083 666.0021 Calcium homeostasis endoplasmic reticulum protein OS=Homo sapiens OX=9606 GN=CHERP PE=1 SV=3 5.4 3351.4 - 939791 - - - 3.2361 - 4.029 0.558 - 545.6 1 2 0 0.0065 18 0 0 0 1.28E+08 1.23E+08 - - - 8.2294 1 221125_WJC_METTL3_EV_vs_WT_F06.21611.21611.3 7.77E-10 24/68 R.QEQVTAAVAHAVEQQMQK[136.11].L "sp|Q8IWX8|CHERP_HUMAN,tr|J3QK89|J3QK89_HUMAN" 2 2002.9986 1.05 88946 21611 3 2002.996321 668.6735 Calcium homeostasis endoplasmic reticulum protein OS=Homo sapiens OX=9606 GN=CHERP PE=1 SV=3 5.4 3351.9 - 2.52E+06 - - - -1.1248 - 4.328 0.613 - 831.2 1 2 0 -0.0023 18 0 0 0 1.28E+08 1.23E+08 - - - 9.022 0.9999 221125_WJC_METTL3_EV_vs_WT_F06.21613.21613.4 7.41E-08 15/102 R.VNFDDYTVNLGGLK[136.11]DHIK[136.11].E "sp|Q06210|GFPT1_HUMAN,tr|A0A6I8PRN4|A0A6I8PRN4_HUMAN,tr|A0A6I8PTT9|A0A6I8PTT9_HUMAN" 3 2063.0659 0.95 88948 21613 4 2063.064371 516.7737 Glutamine--fructose-6-phosphate aminotransferase [isomerizing] 1 OS=Homo sapiens OX=9606 GN=GFPT1 PE=1 SV=3 5.3 3352.2 - 532140 - - - -0.7193 - 3.219 0.493 - 220.8 1 2 1 -0.0015 18 0 0 0 2.55E+07 2.69E+07 - - - 3.9171 1 221125_WJC_METTL3_EV_vs_WT_F06.21615.21615.4 2.47E-05 15/84 K.SYEALVQHVIEDHER.L "sp|Q9H2P0|ADNP_HUMAN,tr|A0A2R8Y6X0|A0A2R8Y6X0_HUMAN,tr|A0A669KBJ7|A0A669KBJ7_HUMAN" 3 1823.8802 1.16 88950 21615 4 1823.878106 456.9773 Activity-dependent neuroprotector homeobox protein OS=Homo sapiens OX=9606 GN=ADNP PE=1 SV=1 4.8 3352.4 - 378576 - - - -1.1624 - 2.293 0.481 - 104.9 1 2 0 -0.0021 15 0 0 0 9.76E+06 8.39E+06 - - - 3.709 1 221125_WJC_METTL3_EV_vs_WT_F06.21618.21618.3 2.32E-13 26/128 R.LFGEAGPASGVGSSGGGGSGSGTGGGDAALDFK[136.11].L "sp|Q8IWZ3|ANKH1_HUMAN,tr|E9PDP5|E9PDP5_HUMAN,tr|D6RHC4|D6RHC4_HUMAN" 3 2791.2776 1.25 88951 21618 3 2791.277128 931.4332 Ankyrin repeat and KH domain-containing protein 1 OS=Homo sapiens OX=9606 GN=ANKHD1 PE=1 SV=1 4.03 3352.8 - 1.25E+06 - - - -0.1852 - 4.29 0.637 - 520.2 1 2 0 -0.0005 33 0 0 0 5.30E+07 4.26E+07 - - - 8.9922 1 221125_WJC_METTL3_EV_vs_WT_F06.21619.21619.3 4.28E-11 22/112 R.AVPSEFANGLSPTPVNGGALDLTSSHAEK.L "sp|Q9NSC2|SALL1_HUMAN,tr|H3BSM9|H3BSM9_HUMAN" 2 2865.4145 2.21 88952 21619 3 2865.418412 956.1454 Sal-like protein 1 OS=Homo sapiens OX=9606 GN=SALL1 PE=1 SV=2 4.65 3353 - 831776 - - - 1.3768 - 4.242 0.644 - 485.3 1 2 0 0.0039 29 0 0 0 2.30E+07 1.04E+07 - - - 9.0434 0.9796 221125_WJC_METTL3_EV_vs_WT_F06.21622.21622.3 0.00708 Nov-88 R.SLETEITNGINLNSDTAEHPGTR[166.11].L "sp|Q92547|TOPB1_HUMAN,tr|A0A2R8YD63|A0A2R8YD63_HUMAN" 2 2478.1862 0.64 88955 21622 3 2478.168547 827.0693 DNA topoisomerase 2-binding protein 1 OS=Homo sapiens OX=9606 GN=TOPBP1 PE=1 SV=3 4.4 3353.3 - 311775 - - - -7.1213 - 2.185 0.345 - 82.5 1 2 0 -0.0176 23 0 0 0 1.53E+06 2.41E+06 - - - 4.2151 0.9354 221125_WJC_METTL3_EV_vs_WT_F06.21625.21625.4 0.00809 13/144 R.C[160.03]GAVGYC[160.03]QGAVWNKPTAKSLPC[160.03]DVC[160.03].Q sp|Q6NUJ1|SAPL1_HUMAN 1 2797.2444 124.64 88956 21625 4 2797.243447 700.3184 Proactivator polypeptide-like 1 OS=Homo sapiens OX=9606 GN=PSAPL1 PE=2 SV=2 7.87 3353.7 - 3.32E+06 - - - -0.3579 - 2.236 0.402 - 23.1 1 1 1 -0.001 25 0 0 0 9.95E+07 7.98E+05 - - - 2.9807 0.9988 221125_WJC_METTL3_EV_vs_WT_F06.21627.21627.3 3.80E-11 28/112 Y.QAQGVLASQALSQGSEPSSENANDTIILR.N sp|P98175|RBM10_HUMAN 1 2983.4847 7.57 88958 21627 3 2983.487673 995.5022 RNA-binding protein 10 OS=Homo sapiens OX=9606 GN=RBM10 PE=1 SV=3 4.14 3353.9 - 2.52E+06 - - - 1.0062 - 4.232 0.577 - 575.8 1 1 0 0.003 29 0 0 0 5.75E+07 7.60E+06 - - - 8.2912 1 221125_WJC_METTL3_EV_vs_WT_F06.21628.21628.4 1.69E-09 21/108 K.SLAVPTIEELEDEEERNHR.Q sp|Q9BVJ6|UT14A_HUMAN 1 2265.0873 1.89 88959 21628 4 2265.088089 567.2791 U3 small nucleolar RNA-associated protein 14 homolog A OS=Homo sapiens OX=9606 GN=UTP14A PE=1 SV=1 4.3 3354 - 1.10E+06 - - - 0.3399 - 3.752 0.636 - 372.7 1 2 1 0.0008 19 0 0 0 1.26E+08 6.70E+07 - - - 5.2088 1 221125_WJC_METTL3_EV_vs_WT_F06.21629.21629.3 1.71E-10 29/124 K.GNDLFSPDEEGPAVVAGPGPGPGGAEGAAEER.R "sp|P35548|MSX2_HUMAN,tr|D6RIS4|D6RIS4_HUMAN" 2 3005.3639 6.38 88960 21629 3 3005.355726 1002.7952 Homeobox protein MSX-2 OS=Homo sapiens OX=9606 GN=MSX2 PE=1 SV=3 3.71 3354.1 - 1.03E+06 - - - -2.7158 - 5.25 0.668 - 702.7 1 2 0 -0.0082 32 0 0 0 6.79E+07 1.06E+07 - - - 9.8003 0.9314 221125_WJC_METTL3_EV_vs_WT_F06.21631.21631.3 0.0555 Aug-68 R.VNFDDYTVNLGGLK[136.11]DHIK[136.11].E "sp|Q06210|GFPT1_HUMAN,tr|A0A6I8PRN4|A0A6I8PRN4_HUMAN,tr|A0A6I8PTT9|A0A6I8PTT9_HUMAN" 3 2063.0659 2.05 88962 21631 3 2063.072713 688.6959 Glutamine--fructose-6-phosphate aminotransferase [isomerizing] 1 OS=Homo sapiens OX=9606 GN=GFPT1 PE=1 SV=3 5.3 3354.4 - 432852 - - - 3.3242 - 1.74 0.232 - 57 1 2 1 0.0069 18 0 0 0 2.00E+07 9.76E+06 - - - 2.5039 1 221125_WJC_METTL3_EV_vs_WT_F06.21635.21635.3 6.10E-07 24/92 K.RYDVGAPSSITISLPGTDPQDAER.R sp|Q12893|TM115_HUMAN 1 2544.2456 1.16 88964 21635 3 2544.246781 849.0891 Transmembrane protein 115 OS=Homo sapiens OX=9606 GN=TMEM115 PE=1 SV=1 4.23 3354.9 - 2.17E+06 - - - 0.4603 - 3.518 0.613 - 366.8 1 2 0 0.0012 24 0 0 0 1.24E+08 1.07E+08 - - - 8.2956 0.9999 221125_WJC_METTL3_EV_vs_WT_F06.21636.21636.3 8.55E-08 20/80 K.DGNVLLHEMQIQHPTASLIAK[136.11].V sp|P40227|TCPZ_HUMAN 1 2322.2246 0.16 88965 21636 3 2322.217245 775.0821 T-complex protein 1 subunit zeta OS=Homo sapiens OX=9606 GN=CCT6A PE=1 SV=3 5.99 3355 - 1.21E+06 - - - -3.1461 - 2.761 0.554 - 402.9 1 2 0 -0.0073 21 0 0 0 6.00E+06 3.70E+07 - - - 7.1494 1 221125_WJC_METTL3_EV_vs_WT_F06.21637.21637.3 5.22E-09 25/92 K.R[166.11]YDVGAPSSITISLPGTDPQDAER[166.11].R sp|Q12893|TM115_HUMAN 1 2564.2622 1.16 88966 21637 3 2564.266941 855.7613 Transmembrane protein 115 OS=Homo sapiens OX=9606 GN=TMEM115 PE=1 SV=1 4.23 3355.1 - 2.01E+06 - - - 1.8684 - 3.963 0.636 - 478.1 1 2 0 0.0048 24 0 0 0 1.24E+08 1.07E+08 - - - 8.8277 0.8611 221125_WJC_METTL3_EV_vs_WT_F06.21641.21641.3 0.164 May-60 K.HTDESLGDC[160.03]SFLNTC[160.03]F.H "sp|Q86U44|MTA70_HUMAN,tr|H0YFV6|H0YFV6_HUMAN" 2 1901.756 - 88970 21641 3 1901.751254 634.9259 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 4.02 3355.6 - 362641 - - - -2.5029 - 1.414 0.383 - 30.3 1 1 0 -0.0048 16 0 0 0 - - - - - 3.6976 1 221125_WJC_METTL3_EV_vs_WT_F06.21644.21644.3 0.00081 14/92 K.LPSSSGNSSSGNYFTPQQTSSFLK.S "sp|Q8NEM7|SP20H_HUMAN,tr|B4E2D5|B4E2D5_HUMAN,tr|R4GND2|R4GND2_HUMAN,tr|H7C5F9|H7C5F9_HUMAN,tr|F6S7C4|F6S7C4_HUMAN" 5 2520.1769 0.99 88971 21644 3 2520.177308 841.0662 Transcription factor SPT20 homolog OS=Homo sapiens OX=9606 GN=SUPT20H PE=1 SV=2 8.59 3356 - 905781 - - - 0.177 - 2.538 0.557 - 136.8 1 2 0 0.0004 24 0 0 0 8.34E+07 8.43E+07 - - - 6.9131 1 221125_WJC_METTL3_EV_vs_WT_F06.21647.21647.4 9.81E-10 27/168 K.TLTSQDDKPLNYGHALLPGEGAAMAEYVK.A "sp|Q8N5F7|NKAP_HUMAN,tr|A0A494C050|A0A494C050_HUMAN" 2 3088.5176 0.53 88974 21647 4 3088.513518 773.1367 NF-kappa-B-activating protein OS=Homo sapiens OX=9606 GN=NKAP PE=1 SV=1 4.75 3356.3 - 2.14E+06 - - - -1.3061 - 4.523 0.575 - 453.1 1 2 0 -0.004 29 0 0 0 2.15E+07 4.03E+07 - - - 4.6948 0.9999 221125_WJC_METTL3_EV_vs_WT_F06.21648.21648.4 1.08E-05 15/108 R.GLLQDDAHPTLVTYADHSK[136.11].L "sp|Q86U44|MTA70_HUMAN,tr|F5H6D8|F5H6D8_HUMAN,tr|H0YFV6|H0YFV6_HUMAN,tr|B4DTN4|B4DTN4_HUMAN" 4 2088.0367 0.01 88975 21648 4 2088.031286 523.0165 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 5.13 3356.4 - 1.77E+06 - - - -2.6087 - 2.764 0.519 - 211.8 1 2 0 -0.0054 19 0 0 0 5.16E+05 8.75E+07 - - - 4.0858 0.991 221125_WJC_METTL3_EV_vs_WT_F06.21649.21649.2 0.00016 13/18 Q.HIVTIVHHVK.E "sp|Q9Y2W1|TR150_HUMAN,tr|A0A3B3ITZ9|A0A3B3ITZ9_HUMAN" 2 1181.7033 3.67 88976 21649 2 1181.703538 591.8589 Thyroid hormone receptor-associated protein 3 OS=Homo sapiens OX=9606 GN=THRAP3 PE=1 SV=2 8.77 3356.5 - 475650 - - - 0.1912 - 2.553 0.386 - 402.9 1 1 0 0.0002 10 0 0 0 3.51E+07 9.55E+06 - - - 4.5081 1 221125_WJC_METTL3_EV_vs_WT_F06.21650.21650.3 1.49E-08 13/96 K.AGTDPSHMPTGPQAASC[160.03]LDLNLVTR[166.11].V "sp|Q9BQG0|MBB1A_HUMAN,tr|I3L1L3|I3L1L3_HUMAN" 2 2618.2456 1.7 88977 21650 3 2618.242412 873.7558 Myb-binding protein 1A OS=Homo sapiens OX=9606 GN=MYBBP1A PE=1 SV=2 5.21 3356.6 - 434720 - - - -1.2333 - 3.126 0.555 - 149.1 1 2 0 -0.0032 25 0 0 0 6.05E+06 3.56E+06 - - - 7.349 1 221125_WJC_METTL3_EV_vs_WT_F06.21654.21654.3 9.66E-15 30/84 K.RGTGGVDTAATGGVFDISNLDR.L sp|P12532|KCRU_HUMAN 1 2178.0665 1.65 88979 21654 3 2178.065422 727.0295 "Creatine kinase U-type, mitochondrial OS=Homo sapiens OX=9606 GN=CKMT1A PE=1 SV=1" 4.43 3357.1 - 1.25E+06 - - - -0.506 - 5.535 0.677 - 1415.1 1 2 0 -0.0011 22 0 0 0 1.99E+07 1.20E+07 - - - 10.1443 0.9999 221125_WJC_METTL3_EV_vs_WT_F06.21656.21656.3 5.13E-07 18/80 K.KQPPQIESFYPPLDEPSIGSK.N "sp|O60934|NBN_HUMAN,tr|A0A0C4DG07|A0A0C4DG07_HUMAN,tr|E5RGR7|E5RGR7_HUMAN" 3 2356.1951 2.68 88981 21656 3 2356.203388 786.4056 Nibrin OS=Homo sapiens OX=9606 GN=NBN PE=1 SV=1 4.68 3357.3 - 1.22E+06 - - - 3.5269 - 3.351 0.51 - 256.1 1 2 0 0.0083 21 0 0 0 2.32E+07 8.64E+06 - - - 7.1228 0.8827 221125_WJC_METTL3_EV_vs_WT_F06.21657.21657.3 0.00832 Dec-40 A.QHIVTIVHHVK.E "sp|Q9Y2W1|TR150_HUMAN,tr|A0A3B3ITZ9|A0A3B3ITZ9_HUMAN" 2 1309.7619 2.52 88982 21657 3 1309.759405 437.5946 Thyroid hormone receptor-associated protein 3 OS=Homo sapiens OX=9606 GN=THRAP3 PE=1 SV=2 8.77 3357.4 - 978476 - - - -1.8965 - 1.938 0.278 - 192 1 1 0 -0.0025 11 0 0 0 5.74E+07 2.28E+07 - - - 3.5184 0.998 221125_WJC_METTL3_EV_vs_WT_F06.21663.21663.4 1.67E-10 22/96 S.PSELFAQHIVTIVHHVK.E "sp|Q9Y2W1|TR150_HUMAN,tr|A0A3B3ITZ9|A0A3B3ITZ9_HUMAN" 2 1954.0789 2.44 88986 21663 4 1954.078505 489.527 Thyroid hormone receptor-associated protein 3 OS=Homo sapiens OX=9606 GN=THRAP3 PE=1 SV=2 7.42 3358.1 - 4.24E+06 - - - -0.1847 - 3.784 0.57 - 462.1 1 1 0 -0.0004 17 0 0 0 1.75E+08 7.17E+07 - - - 4.6492 1 221125_WJC_METTL3_EV_vs_WT_F06.21666.21666.3 2.47E-12 28/88 K.ARENPSEEAQNLVEFTDEEGYGR.Y sp|Q12874|SF3A3_HUMAN 1 2639.1736 4.43 88989 21666 3 2639.166091 880.7318 Splicing factor 3A subunit 3 OS=Homo sapiens OX=9606 GN=SF3A3 PE=1 SV=1 4.06 3358.5 - 1.98E+06 - - - -2.8331 - 5.602 0.713 - 1257.6 1 2 1 -0.0075 23 0 0 0 1.10E+08 2.49E+07 - - - 10.5295 1 221125_WJC_METTL3_EV_vs_WT_F06.21669.21669.3 2.77E-10 39/124 K.VGGTNLGAPGAFGQSPFSQPPAPPHQNTFPPR.S sp|Q96I24|FUBP3_HUMAN 1 3227.5901 2.64 88991 21669 3 3227.587827 1076.8706 Far upstream element-binding protein 3 OS=Homo sapiens OX=9606 GN=FUBP3 PE=1 SV=2 9.73 3358.8 - 3.81E+06 - - - -0.698 - 4.882 0.666 - 995 1 2 0 -0.0023 32 0 0 0 3.03E+08 1.15E+08 - - - 9.6124 1 221125_WJC_METTL3_EV_vs_WT_F06.21672.21672.3 2.86E-09 22/60 P.SELFAQHIVTIVHHVK.E "sp|Q9Y2W1|TR150_HUMAN,tr|A0A3B3ITZ9|A0A3B3ITZ9_HUMAN" 2 1857.0261 4.09 88993 21672 3 1857.02218 620.016 Thyroid hormone receptor-associated protein 3 OS=Homo sapiens OX=9606 GN=THRAP3 PE=1 SV=2 6.78 3359.1 - 1.30E+06 - - - -2.1125 - 3.464 0.606 - 496.2 1 1 0 -0.0039 16 0 0 0 8.29E+07 2.03E+07 - - - 8.4831 1 221125_WJC_METTL3_EV_vs_WT_F06.21673.21673.3 3.03E-12 23/92 K.LPSSSGNSSSGNYFTPQQTSSFLK[136.11].S "sp|Q8NEM7|SP20H_HUMAN,tr|B4E2D5|B4E2D5_HUMAN,tr|R4GND2|R4GND2_HUMAN,tr|H7C5F9|H7C5F9_HUMAN,tr|F6S7C4|F6S7C4_HUMAN" 5 2528.1911 1.1 88994 21673 3 2528.186865 843.7376 Transcription factor SPT20 homolog OS=Homo sapiens OX=9606 GN=SUPT20H PE=1 SV=2 8.59 3359.3 - 1.35E+06 - - - -1.6601 - 4.088 0.688 - 430.5 1 2 0 -0.0042 24 0 0 0 7.63E+07 6.93E+07 - - - 9.4797 1 221125_WJC_METTL3_EV_vs_WT_F06.21679.21679.4 3.58E-09 19/102 R.SPSELFAQHIVTIVHHVK.E "sp|Q9Y2W1|TR150_HUMAN,tr|A0A3B3ITZ9|A0A3B3ITZ9_HUMAN" 2 2041.1109 2.75 88997 21679 4 2041.110572 511.285 Thyroid hormone receptor-associated protein 3 OS=Homo sapiens OX=9606 GN=THRAP3 PE=1 SV=2 6.78 3360 - 3.58E+08 - - - -0.1582 - 3.2 0.601 - 239.7 1 2 0 -0.0003 18 0 0 0 1.87E+10 6.82E+09 - - - 4.8555 1 221125_WJC_METTL3_EV_vs_WT_F06.21681.21681.4 8.15E-07 28/186 K.VGGTNLGAPGAFGQSPFSQPPAPPHQNTFPPR.S sp|Q96I24|FUBP3_HUMAN 1 3227.5901 2.23 88998 21681 4 3227.585174 807.9048 Far upstream element-binding protein 3 OS=Homo sapiens OX=9606 GN=FUBP3 PE=1 SV=2 9.73 3360.2 - 4.38E+06 - - - -1.52 - 4.893 0.547 - 233.8 1 2 0 -0.0049 32 0 0 0 1.98E+08 8.90E+07 - - - 4.4651 1 221125_WJC_METTL3_EV_vs_WT_F06.21692.21692.4 1.31E-10 36/186 K.VGGTNLGAPGAFGQSPFSQPPAPPHQNTFPPR[166.11].S sp|Q96I24|FUBP3_HUMAN 1 3237.5984 2.32 89003 21692 4 3237.59873 810.4069 Far upstream element-binding protein 3 OS=Homo sapiens OX=9606 GN=FUBP3 PE=1 SV=2 9.73 3361.6 - 2.31E+06 - - - 0.1174 - 4.689 0.565 - 450.7 1 2 0 0.0004 32 0 0 0 3.00E+08 1.29E+08 - - - 4.6102 1 221125_WJC_METTL3_EV_vs_WT_F06.21694.21694.4 4.11E-12 23/96 S.PSELFAQHIVTIVHHVK[136.11].E "sp|Q9Y2W1|TR150_HUMAN,tr|A0A3B3ITZ9|A0A3B3ITZ9_HUMAN" 2 1962.0931 2.87 89004 21694 4 1962.091652 491.5305 Thyroid hormone receptor-associated protein 3 OS=Homo sapiens OX=9606 GN=THRAP3 PE=1 SV=2 7.42 3361.8 - 1.20E+06 - - - -0.7207 - 3.958 0.615 - 455.9 1 1 0 -0.0014 17 0 0 0 1.64E+08 5.73E+07 - - - 5.0562 1 221125_WJC_METTL3_EV_vs_WT_F06.21698.21698.4 1.45E-06 21/132 R.LVRPEVDVMC[160.03]TAFHDNEETFLKK.Y "sp|P02768|ALBU_HUMAN,tr|A0A087WWT3|A0A087WWT3_HUMAN,tr|H7C013|H7C013_HUMAN,tr|A0A0C4DGB6|A0A0C4DGB6_HUMAN" 4 2777.3517 4.34 89005 21698 4 2777.347866 695.3452 Albumin OS=Homo sapiens OX=9606 GN=ALB PE=1 SV=2 4.9 3362.4 - 1.97E+06 - - - -1.3704 - 3.483 0.522 - 227.9 1 2 0 -0.0038 23 0 0 0 8.39E+07 1.94E+07 - - - 4.1727 0.9961 221125_WJC_METTL3_EV_vs_WT_F06.21699.21699.4 1.56E-09 18/72 L.FAQHIVTIVHHVK[136.11].E "sp|Q9Y2W1|TR150_HUMAN,tr|A0A3B3ITZ9|A0A3B3ITZ9_HUMAN" 2 1535.8816 2.32 89006 21699 4 1535.879876 384.9777 Thyroid hormone receptor-associated protein 3 OS=Homo sapiens OX=9606 GN=THRAP3 PE=1 SV=2 8.77 3362.5 - 630221 - - - -1.1336 - 2.559 0.506 - 134.8 1 1 0 -0.0017 13 0 0 0 6.77E+07 2.92E+07 - - - 3.9781 1 221125_WJC_METTL3_EV_vs_WT_F06.21704.21704.3 3.77E-09 30/124 K.VGGTNLGAPGAFGQSPFSQPPAPPHQNTFPPR[166.11].S sp|Q96I24|FUBP3_HUMAN 1 3237.5984 2.95 89007 21704 3 3237.593173 1080.2067 Far upstream element-binding protein 3 OS=Homo sapiens OX=9606 GN=FUBP3 PE=1 SV=2 9.73 3363.2 - 1.60E+06 - - - -1.599 - 4.109 0.616 - 639.5 1 2 0 -0.0052 32 0 0 0 1.68E+08 5.70E+07 - - - 8.6576 1 221125_WJC_METTL3_EV_vs_WT_F06.21707.21707.3 4.66E-06 26/64 R.HGVQELEIELQSQLSKK.A "sp|P35527|K1C9_HUMAN,tr|K7EQQ3|K7EQQ3_HUMAN" 2 1965.0531 999 89009 21707 3 1965.051129 656.025 "Keratin, type I cytoskeletal 9 OS=Homo sapiens OX=9606 GN=KRT9 PE=1 SV=3" 5.5 3363.5 - 2.90E+06 - - - -1.0056 - 4.867 0.636 - 1145 1 2 0 -0.002 17 0 0 0 1.82E+09 0.00E+00 - - - 9.628 0.9999 221125_WJC_METTL3_EV_vs_WT_F06.21712.21712.4 0.000215 12/126 R.EDEDPHRPPTSEELLTAYGYMR.G "sp|Q9H089|LSG1_HUMAN,tr|H7C2X7|H7C2X7_HUMAN" 2 2605.1755 0.48 89012 21712 4 2605.178533 652.3011 Large subunit GTPase 1 homolog OS=Homo sapiens OX=9606 GN=LSG1 PE=1 SV=2 4.35 3364.1 - 1.73E+06 - - - 1.1711 - 2.019 0.409 - 53.6 1 2 0 0.0031 22 0 0 0 4.10E+07 8.51E+07 - - - 3.015 0.9996 221125_WJC_METTL3_EV_vs_WT_F06.21713.21713.4 0.00144 16/108 K.GSKEEQRDYVFYLAVGNYR.L sp|Q9Y3D6|FIS1_HUMAN 1 2293.1127 1.8 89013 21713 4 2293.111655 574.2855 Mitochondrial fission 1 protein OS=Homo sapiens OX=9606 GN=FIS1 PE=1 SV=2 6.18 3364.2 - 1.01E+06 - - - -0.4753 - 3.001 0.409 - 174.5 1 2 2 -0.0011 19 0 0 0 3.97E+07 2.20E+07 - - - 3.1574 0.9999 221125_WJC_METTL3_EV_vs_WT_F06.21718.21718.4 3.83E-06 20/132 K.IYITLTGVHQVPTENVQVHFTER[166.11].S sp|Q9HB71|CYBP_HUMAN 1 2690.4056 0.48 89015 21718 4 2690.413124 673.6087 Calcyclin-binding protein OS=Homo sapiens OX=9606 GN=CACYBP PE=1 SV=2 6 3364.8 - 1.00E+06 - - - 2.8078 - 3.73 0.535 - 178 1 2 0 0.0076 23 0 0 0 7.20E+06 1.49E+07 - - - 4.307 0.9999 221125_WJC_METTL3_EV_vs_WT_F06.21720.21720.4 3.16E-05 25/102 R.NPVWYQALTHGLNEEQR[166.11]K[136.11].Q sp|O95373|IPO7_HUMAN 1 2200.1144 2.61 89016 21720 4 2200.107369 551.0359 Importin-7 OS=Homo sapiens OX=9606 GN=IPO7 PE=1 SV=1 6.76 3365 - 1.08E+06 - - - -3.2048 - 3.413 0.477 - 716.1 1 2 0 -0.0071 18 0 0 0 6.76E+07 2.59E+07 - - - 3.7964 0.9997 221125_WJC_METTL3_EV_vs_WT_F06.21723.21723.4 1.08E-08 17/108 K.SLAVPTIEELEDEEER[166.11]NHR[166.11].Q sp|Q9BVJ6|UT14A_HUMAN 1 2285.1039 1.93 89017 21723 4 2285.096013 572.2832 U3 small nucleolar RNA-associated protein 14 homolog A OS=Homo sapiens OX=9606 GN=UTP14A PE=1 SV=1 4.3 3365.4 - 1.25E+06 - - - -3.4335 - 3.694 0.57 - 218.5 1 2 1 -0.0078 19 0 0 0 1.08E+08 5.61E+07 - - - 4.6271 1 221125_WJC_METTL3_EV_vs_WT_F06.21726.21726.4 9.26E-17 34/138 R.HAMNLEAVNTYEGTHDIHALILGR.A sp|Q92947|GCDH_HUMAN 1 2674.3286 1.21 89019 21726 4 2674.330831 669.5894 "Glutaryl-CoA dehydrogenase, mitochondrial OS=Homo sapiens OX=9606 GN=GCDH PE=1 SV=1" 5.75 3365.8 - 1.51E+06 - - - 0.8458 - 5.958 0.716 - 1131.4 1 2 0 0.0023 24 0 0 0 1.28E+08 1.06E+08 - - - 6.0303 1 221125_WJC_METTL3_EV_vs_WT_F06.21728.21728.3 9.04E-12 18/92 K.NQC[160.03]C[160.03]PIC[160.03]NMTFSSPVVAQSHYLGK.T "sp|Q9UL40|ZN346_HUMAN,tr|D6RJ07|D6RJ07_HUMAN" 2 2797.2444 1.76 89021 21728 3 2798.25182 933.4221 Zinc finger protein 346 OS=Homo sapiens OX=9606 GN=ZNF346 PE=1 SV=1 7.96 3366 - 742650 - - - 360.1305 - 3.158 0.691 - 147 1 2 0 1.0074 24 0 0 0 2.37E+07 1.34E+07 - - - 8.6358 0.9986 221125_WJC_METTL3_EV_vs_WT_F06.21729.21729.3 2.86E-08 17/60 P.SELFAQHIVTIVHHVK[136.11].E "sp|Q9Y2W1|TR150_HUMAN,tr|A0A3B3ITZ9|A0A3B3ITZ9_HUMAN" 2 1865.0403 4.02 89022 21729 3 1865.039173 622.6874 Thyroid hormone receptor-associated protein 3 OS=Homo sapiens OX=9606 GN=THRAP3 PE=1 SV=2 6.78 3366.2 - 669637 - - - -0.6059 - 3.299 0.553 - 313.4 1 1 0 -0.0011 16 0 0 0 8.15E+07 2.03E+07 - - - 7.7678 1 221125_WJC_METTL3_EV_vs_WT_F06.21731.21731.4 9.78E-08 19/102 R.SPSELFAQHIVTIVHHVK[136.11].E "sp|Q9Y2W1|TR150_HUMAN,tr|A0A3B3ITZ9|A0A3B3ITZ9_HUMAN" 2 2049.1251 2.75 89023 21731 4 2049.118956 513.2886 Thyroid hormone receptor-associated protein 3 OS=Homo sapiens OX=9606 GN=THRAP3 PE=1 SV=2 6.78 3366.4 - 1.26E+08 - - - -2.9959 - 3.397 0.577 - 250.2 1 2 0 -0.0061 18 0 0 0 1.87E+10 6.81E+09 - - - 4.6654 1 221125_WJC_METTL3_EV_vs_WT_F06.21733.21733.4 1.11E-07 20/96 R.HGVQELEIELQSQLSKK.A "sp|P35527|K1C9_HUMAN,tr|K7EQQ3|K7EQQ3_HUMAN" 2 1965.0531 211.57 89024 21733 4 1965.050378 492.2706 "Keratin, type I cytoskeletal 9 OS=Homo sapiens OX=9606 GN=KRT9 PE=1 SV=3" 5.5 3366.6 - 1.98E+06 - - - -1.3877 - 3.366 0.473 - 375.2 1 2 0 -0.0027 17 0 0 0 1.49E+08 7.03E+05 - - - 3.7636 1 221125_WJC_METTL3_EV_vs_WT_F06.21734.21734.3 5.09E-08 13/92 K.DNLELPSAEHQAIESSQASVETWK.Y "sp|Q96DF8|ESS2_HUMAN,tr|F8WEF8|F8WEF8_HUMAN" 2 2668.2617 1.9 89025 21734 3 2668.259129 890.4278 Splicing factor ESS-2 homolog OS=Homo sapiens OX=9606 GN=ESS2 PE=1 SV=1 4.25 3366.7 - 749363 - - - -0.9463 - 3.218 0.593 - 122.9 1 2 0 -0.0025 24 0 0 0 5.71E+07 3.01E+07 - - - 7.8652 1 221125_WJC_METTL3_EV_vs_WT_F06.21735.21735.4 1.58E-19 24/138 R.HAMNLEAVNTYEGTHDIHALILGR[166.11].A sp|Q92947|GCDH_HUMAN 1 2684.3368 1.2 89026 21735 4 2684.331325 672.0915 "Glutaryl-CoA dehydrogenase, mitochondrial OS=Homo sapiens OX=9606 GN=GCDH PE=1 SV=1" 5.75 3366.8 - 2.40E+06 - - - -2.0541 - 5.374 0.714 - 481.4 1 2 0 -0.0055 24 0 0 0 1.28E+08 1.06E+08 - - - 5.9789 1 221125_WJC_METTL3_EV_vs_WT_F06.21739.21739.3 1.75E-15 31/92 K.DIIEHLNTSGAPADTSDPLQQIC[160.03]K.L "sp|P37198|NUP62_HUMAN,tr|M0QXN5|M0QXN5_HUMAN" 2 2622.2595 1.44 89028 21739 3 2622.251679 875.0938 Nuclear pore glycoprotein p62 OS=Homo sapiens OX=9606 GN=NUP62 PE=1 SV=3 4.22 3367.3 - 1.53E+06 - - - -3.0001 - 4.906 0.652 - 1086.3 1 2 0 -0.0079 24 0 0 0 1.13E+08 7.89E+07 - - - 9.501 1 221125_WJC_METTL3_EV_vs_WT_F06.21741.21741.4 2.15E-05 27/240 K.ATVPVAAATAAEGEGSPPAVAAVAGPPAAAEVGGGVGGSSR.A "sp|O75179|ANR17_HUMAN,tr|A0A1W2PQ15|A0A1W2PQ15_HUMAN,tr|H0YLQ3|H0YLQ3_HUMAN" 3 3483.7594 316.72 89030 21741 4 3483.759525 871.9471 Ankyrin repeat domain-containing protein 17 OS=Homo sapiens OX=9606 GN=ANKRD17 PE=1 SV=3 4.25 3367.5 - 1.16E+06 - - - 0.0388 - 4.524 0.545 - 289 1 2 0 0.0001 41 0 0 0 4.57E+07 1.44E+05 - - - 4.4032 0.9997 221125_WJC_METTL3_EV_vs_WT_F06.21746.21746.3 5.34E-06 13/64 K.DKPNPQLIYDDEIPSLK.L "sp|Q9Y2L1|RRP44_HUMAN,tr|G3V1J5|G3V1J5_HUMAN" 2 1984.0153 3.12 89033 21746 3 1984.011633 662.3457 Exosome complex exonuclease RRP44 OS=Homo sapiens OX=9606 GN=DIS3 PE=1 SV=2 4.23 3368.2 - 716074 - - - -1.8599 - 2.625 0.328 - 159.3 1 2 0 -0.0037 17 0 0 0 2.15E+07 6.88E+06 - - - 4.6339 1 221125_WJC_METTL3_EV_vs_WT_F06.21750.21750.2 1.21E-17 21/40 R.SSSSC[160.03]NLGSSLSGFAVATGGR.G sp|P0CG40|SP9_HUMAN 1 2000.9222 1.95 89035 21750 2 2000.923886 1001.4684 Transcription factor Sp9 OS=Homo sapiens OX=9606 GN=SP9 PE=3 SV=1 7.96 3368.7 - 889587 - - - 0.8586 - 4.131 0.782 - 999.5 1 2 0 0.0017 21 0 0 0 2.17E+07 1.11E+07 - - - 8.3038 0.9999 221125_WJC_METTL3_EV_vs_WT_F06.21752.21752.4 8.08E-07 16/132 K.GVEAIPEGSHIKDNEQALYELVK.C sp|Q8N108|MIER1_HUMAN 1 2538.2966 1.15 89037 21752 4 2538.293099 635.5814 Mesoderm induction early response protein 1 OS=Homo sapiens OX=9606 GN=MIER1 PE=1 SV=2 4.57 3369 - 761148 - - - -1.3726 - 3.107 0.53 - 149.5 1 2 1 -0.0035 23 0 0 0 1.59E+07 1.38E+07 - - - 4.2054 0.9994 221125_WJC_METTL3_EV_vs_WT_F06.21756.21756.3 4.20E-09 18/96 K.LVQDVANNTNEEAGDGTTTATVLAR.S "sp|P10809|CH60_HUMAN,tr|C9JL25|C9JL25_HUMAN,tr|A0A7I2V2X6|A0A7I2V2X6_HUMAN,tr|A0A7I2YQK6|A0A7I2YQK6_HUMAN,tr|A0A7I2V599|A0A7I2V599_HUMAN,tr|E7EXB4|E7EXB4_HUMAN,tr|A0A7I2YQ71|A0A7I2YQ71_HUMAN,tr|E7ESH4|E7ESH4_HUMAN,tr|A0A7I2V5M1|A0A7I2V5M1_HUMAN,tr|A0A7I2V5K3|A0A7I2V5K3_HUMAN,tr|A0A7I2V369|A0A7I2V369_HUMAN" 11 2559.2413 1.5 89039 21756 3 2559.223149 854.0877 "60 kDa heat shock protein, mitochondrial OS=Homo sapiens OX=9606 GN=HSPD1 PE=1 SV=2" 3.92 3369.5 - 1.16E+06 - - - -7.074 - 3.546 0.628 - 349.7 1 2 0 -0.0181 25 0 0 0 2.70E+07 1.80E+07 - - - 8.4488 1 221125_WJC_METTL3_EV_vs_WT_F06.21757.21757.4 5.23E-08 21/102 R.NPVWYQALTHGLNEEQRK.Q sp|O95373|IPO7_HUMAN 1 2182.0919 2.61 89040 21757 4 2182.090447 546.5303 Importin-7 OS=Homo sapiens OX=9606 GN=IPO7 PE=1 SV=1 6.76 3369.6 - 2.06E+06 - - - -0.6888 - 3.876 0.541 - 507.5 1 2 0 -0.0015 18 0 0 0 6.82E+07 2.62E+07 - - - 4.3985 1 221125_WJC_METTL3_EV_vs_WT_F06.21767.21767.3 2.21E-10 19/68 R.SPSELFAQHIVTIVHHVK.E "sp|Q9Y2W1|TR150_HUMAN,tr|A0A3B3ITZ9|A0A3B3ITZ9_HUMAN" 2 2041.1109 2.61 89046 21767 3 2041.110665 681.3776 Thyroid hormone receptor-associated protein 3 OS=Homo sapiens OX=9606 GN=THRAP3 PE=1 SV=2 6.78 3370.8 - 2.59E+07 - - - -0.1127 - 3.963 0.652 - 463.4 1 2 0 -0.0002 18 0 0 0 3.77E+09 1.44E+09 - - - 9.238 1 221125_WJC_METTL3_EV_vs_WT_F06.21769.21769.3 7.55E-10 18/68 K.YVHYEIDAC[160.03]MDSEAPGSK[136.11].D "sp|Q86U44|MTA70_HUMAN,tr|H0YFV6|H0YFV6_HUMAN" 2 2078.8805 0.001 89047 21769 3 2079.879287 693.9674 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 4.31 3371 - 1.54E+06 - - - 480.4485 - 3.535 0.679 - 357.5 1 2 0 0.9988 18 0 0 0 0.00E+00 3.94E+07 - - - 8.9778 1 221125_WJC_METTL3_EV_vs_WT_F06.21770.21770.2 3.00E-16 21/32 R.HGVQELEIELQSQLSKK.A "sp|P35527|K1C9_HUMAN,tr|K7EQQ3|K7EQQ3_HUMAN" 2 1965.0531 999 89048 21770 2 1965.053402 983.5338 "Keratin, type I cytoskeletal 9 OS=Homo sapiens OX=9606 GN=KRT9 PE=1 SV=3" 5.5 3371.1 - 255780 - - - 0.1511 - 4.629 0.695 - 1153.2 1 2 0 0.0003 17 0 0 0 5.87E+06 0.00E+00 - - - 7.9415 1 221125_WJC_METTL3_EV_vs_WT_F06.21773.21773.3 1.20E-08 20/80 R.GVDC[160.03]LSSHFQELSIYQDQEQR[166.11].L "sp|P55265|DSRAD_HUMAN,tr|A0A3B3IRQ9|A0A3B3IRQ9_HUMAN,tr|A0A3B3ISU1|A0A3B3ISU1_HUMAN,tr|A0A7P0Z4K3|A0A7P0Z4K3_HUMAN,tr|A0A3B3ISX1|A0A3B3ISX1_HUMAN" 5 2548.1528 0.63 89051 21773 3 2548.14866 850.3915 Double-stranded RNA-specific adenosine deaminase OS=Homo sapiens OX=9606 GN=ADAR PE=1 SV=4 4.31 3371.5 - 860126 - - - -1.6192 - 3.677 0.556 - 411.3 1 2 0 -0.0041 21 0 0 0 1.19E+07 1.89E+07 - - - 7.8594 0.9998 221125_WJC_METTL3_EV_vs_WT_F06.21774.21774.4 4.53E-08 15/132 K.GVEAIPEGSHIK[136.11]DNEQALYELVK[136.11].C sp|Q8N108|MIER1_HUMAN 1 2554.325 1.15 89052 21774 4 2554.32233 639.5885 Mesoderm induction early response protein 1 OS=Homo sapiens OX=9606 GN=MIER1 PE=1 SV=2 4.57 3371.6 - 848413 - - - -1.0386 - 3.11 0.473 - 127.2 1 2 1 -0.0027 23 0 0 0 1.55E+07 1.36E+07 - - - 3.7099 1 221125_WJC_METTL3_EV_vs_WT_F06.21778.21778.4 6.00E-09 16/120 K.SGDTLLLLHHGDFSAEEVFHR.E "sp|Q9BTV4|TMM43_HUMAN,tr|V9GY05|V9GY05_HUMAN" 2 2379.1608 1.16 89054 21778 4 2379.166425 595.7975 Transmembrane protein 43 OS=Homo sapiens OX=9606 GN=TMEM43 PE=1 SV=1 5.21 3372.1 - 383457 - - - 2.3819 - 2.918 0.544 - 163.4 1 2 0 0.0057 21 0 0 0 2.29E+07 1.97E+07 - - - 4.3135 0.9074 221125_WJC_METTL3_EV_vs_WT_F06.21790.21790.4 1.28E-05 18/126 K.LKDDQTLDFYGIQPGSTVHVLR.K "sp|Q96S82|UBL7_HUMAN,tr|H3BV23|H3BV23_HUMAN,tr|H3BUV9|H3BUV9_HUMAN" 3 2501.2914 5.54 89060 21790 4 2501.313356 626.3301 Ubiquitin-like protein 7 OS=Homo sapiens OX=9606 GN=UBL7 PE=1 SV=2 5.3 3373.7 - 680773 - - - 8.7627 - 3.113 0.346 - 194.1 1 2 1 0.0219 22 0 0 0 6.38E+06 1.15E+06 - - - 2.6031 0.9997 221125_WJC_METTL3_EV_vs_WT_F06.21793.21793.3 3.79E-14 26/92 K.DIIEHLNTSGAPADTSDPLQQIC[160.03]K[136.11].L "sp|P37198|NUP62_HUMAN,tr|M0QXN5|M0QXN5_HUMAN" 2 2630.2737 2.13 89063 21793 3 2631.27519 877.7652 Nuclear pore glycoprotein p62 OS=Homo sapiens OX=9606 GN=NUP62 PE=1 SV=3 4.22 3374 - 1.78E+06 - - - 380.7376 - 4.496 0.596 - 711.2 1 2 0 1.0014 24 0 0 0 1.12E+08 5.23E+07 - - - 8.3987 1 221125_WJC_METTL3_EV_vs_WT_F06.21797.21797.3 4.00E-08 21/68 R.SPSELFAQHIVTIVHHVK[136.11].E "sp|Q9Y2W1|TR150_HUMAN,tr|A0A3B3ITZ9|A0A3B3ITZ9_HUMAN" 2 2049.1251 2.61 89066 21797 3 2049.125689 684.049 Thyroid hormone receptor-associated protein 3 OS=Homo sapiens OX=9606 GN=THRAP3 PE=1 SV=2 6.78 3374.4 - 4.76E+06 - - - 0.2899 - 4.16 0.628 - 646.6 1 2 0 0.0006 18 0 0 0 3.76E+09 1.44E+09 - - - 9.0911 1 221125_WJC_METTL3_EV_vs_WT_F06.21800.21800.4 3.72E-09 18/96 R.DLIGHIVEFSQDQHGSR.F "sp|Q8TB72|PUM2_HUMAN,tr|A0A0C4DG68|A0A0C4DG68_HUMAN" 2 1936.9391 1.42 89069 21800 4 1936.940895 485.2421 Pumilio homolog 2 OS=Homo sapiens OX=9606 GN=PUM2 PE=1 SV=2 5.21 3374.7 - 559278 - - - 0.9071 - 3.309 0.617 - 166.3 1 2 0 0.0018 17 0 0 0 5.48E+06 3.85E+06 - - - 5.0114 0.996 221125_WJC_METTL3_EV_vs_WT_F06.21801.21801.4 0.00148 13/102 K.IK[136.11]VDEFVTHNLSFDEINK[136.11].A sp|P11766|ADHX_HUMAN 1 2163.1183 1.46 89070 21801 4 2163.122707 541.7868 Alcohol dehydrogenase class-3 OS=Homo sapiens OX=9606 GN=ADH5 PE=1 SV=4 4.75 3374.9 - 546378 - - - 2.0443 - 2.684 0.31 - 142 1 2 1 0.0044 18 0 0 0 8.40E+06 5.76E+06 - - - 2.2612 1 221125_WJC_METTL3_EV_vs_WT_F06.21805.21805.4 1.48E-11 24/120 K.SGDTLLLLHHGDFSAEEVFHR[166.11].E "sp|Q9BTV4|TMM43_HUMAN,tr|V9GY05|V9GY05_HUMAN" 2 2389.169 1.16 89072 21805 4 2389.173459 598.2995 Transmembrane protein 43 OS=Homo sapiens OX=9606 GN=TMEM43 PE=1 SV=1 5.21 3375.3 - 1.45E+06 - - - 1.8546 - 4.317 0.635 - 496.1 1 2 0 0.0044 21 0 0 0 2.29E+07 1.97E+07 - - - 5.2354 1 221125_WJC_METTL3_EV_vs_WT_F06.21808.21808.3 2.81E-11 19/92 K.DNLELPSAEHQAIESSQASVETWK[136.11].Y "sp|Q96DF8|ESS2_HUMAN,tr|F8WEF8|F8WEF8_HUMAN" 2 2676.2759 1.9 89075 21808 3 2676.276898 893.0992 Splicing factor ESS-2 homolog OS=Homo sapiens OX=9606 GN=ESS2 PE=1 SV=1 4.25 3375.6 - 1.29E+06 - - - 0.3901 - 3.834 0.678 - 273.5 1 2 0 0.001 24 0 0 0 5.71E+07 3.01E+07 - - - 9.2201 1 221125_WJC_METTL3_EV_vs_WT_F06.21810.21810.3 3.85E-15 24/88 R.SPTEQEEPDPANLEVDHDFFQDK.V sp|Q96CU9|FXRD1_HUMAN 1 2686.1671 1.3 89077 21810 3 2686.167511 896.3963 FAD-dependent oxidoreductase domain-containing protein 1 OS=Homo sapiens OX=9606 GN=FOXRED1 PE=1 SV=2 3.84 3375.9 - 849277 - - - 0.1586 - 5.021 0.748 - 667.3 1 2 0 0.0004 23 0 0 0 1.25E+07 9.64E+06 - - - 10.6648 0.9209 221125_WJC_METTL3_EV_vs_WT_F06.21812.21812.4 1.1 13/186 R.NSPGLGSLVSPHGPHMPPAASIPPPPGLGGVK[136.11].A "sp|Q8ND24|RN214_HUMAN,tr|E9PN76|E9PN76_HUMAN" 2 3029.6 7.91 89079 21812 4 3029.590022 758.4073 RING finger protein 214 OS=Homo sapiens OX=9606 GN=RNF214 PE=1 SV=2 8.76 3376.1 - 2.01E+06 - - - -3.3087 - 1.547 0.177 - 34.7 1 2 0 -0.01 32 0 0 0 4.86E+07 6.14E+06 - - - 0.8956 0.9989 221125_WJC_METTL3_EV_vs_WT_F06.21816.21816.3 2.98E-08 18/44 F.AQHIVTIVHHVK.E "sp|Q9Y2W1|TR150_HUMAN,tr|A0A3B3ITZ9|A0A3B3ITZ9_HUMAN" 2 1380.799 2.5 89082 21816 3 1380.79736 461.2736 Thyroid hormone receptor-associated protein 3 OS=Homo sapiens OX=9606 GN=THRAP3 PE=1 SV=2 8.81 3376.6 - 473344 - - - -1.1899 - 3.137 0.604 - 368 1 1 0 -0.0016 12 0 0 0 5.15E+08 2.06E+08 - - - 8.4425 0.9982 221125_WJC_METTL3_EV_vs_WT_F06.21822.21822.3 6.84E-14 31/112 P.VAPAPAAPTPAAPAPAPSWPLSSSVPSQK.T "sp|P04637|P53_HUMAN,tr|J3KP33|J3KP33_HUMAN,tr|S4R334|S4R334_HUMAN,tr|A0A0U1RQC9|A0A0U1RQC9_HUMAN,tr|E7EQX7|E7EQX7_HUMAN,tr|E9PCY9|E9PCY9_HUMAN,tr|E7EMR6|E7EMR6_HUMAN" 7 2749.4439 1.38 89087 21822 3 2749.448311 917.4886 Cellular tumor antigen p53 OS=Homo sapiens OX=9606 GN=TP53 PE=1 SV=4 8.72 3377.2 - 1.06E+06 - - - 1.5985 - 4.749 0.533 - 639.5 1 1 0 0.0044 29 0 0 0 3.93E+07 2.84E+07 - - - 8.0655 0.9997 221125_WJC_METTL3_EV_vs_WT_F06.21823.21823.4 0.00131 29/132 R.HLMELNALDK[136.11]QEELTPLGVHLAR[166.11].L "sp|Q9H2U1|DHX36_HUMAN,tr|E7EWK3|E7EWK3_HUMAN" 2 2644.4126 1.08 89088 21823 4 2644.420383 662.1104 ATP-dependent DNA\RNA helicase DHX36 OS=Homo sapiens OX=9606 GN=DHX36 PE=1 SV=2 5.36 3377.3 - 1.00E+06 - - - 2.9523 - 4.143 0.528 - 732.3 1 2 1 0.0078 23 0 0 0 1.00E+07 9.30E+06 - - - 4.2801 1 221125_WJC_METTL3_EV_vs_WT_F06.21825.21825.3 4.42E-13 29/112 P.VAPAPAAPTPAAPAPAPSWPLSSSVPSQK[136.11].T "sp|P04637|P53_HUMAN,tr|J3KP33|J3KP33_HUMAN,tr|S4R334|S4R334_HUMAN,tr|A0A0U1RQC9|A0A0U1RQC9_HUMAN,tr|E7EQX7|E7EQX7_HUMAN,tr|E9PCY9|E9PCY9_HUMAN,tr|E7EMR6|E7EMR6_HUMAN" 7 2757.4581 1.38 89090 21825 3 2757.461913 920.16 Cellular tumor antigen p53 OS=Homo sapiens OX=9606 GN=TP53 PE=1 SV=4 8.72 3377.6 - 808791 - - - 1.377 - 4.844 0.604 - 600.4 1 1 0 0.0038 29 0 0 0 3.93E+07 2.84E+07 - - - 8.9028 0.9988 221125_WJC_METTL3_EV_vs_WT_F06.21827.21827.3 0.000934 Dec-84 K.EIEQEAAVELSQLR[166.11]DPQHDLDR[166.11].V sp|P47985|UCRI_HUMAN 1 2610.2789 3.69 89092 21827 3 2610.284077 871.1002 "Cytochrome b-c1 complex subunit Rieske, mitochondrial OS=Homo sapiens OX=9606 GN=UQCRFS1 PE=1 SV=2" 4.19 3377.8 - 473410 - - - 1.9975 - 2.711 0.358 - 146.8 1 2 1 0.0052 22 0 0 0 2.35E+07 6.37E+06 - - - 4.8944 1 221125_WJC_METTL3_EV_vs_WT_F06.21828.21828.4 1.48E-07 19/114 K.GIHHPTPIQIQGIPTILSGR[166.11].D "sp|Q9UJV9|DDX41_HUMAN,tr|A0A499FJW5|A0A499FJW5_HUMAN,tr|H0Y8L8|H0Y8L8_HUMAN" 3 2144.2094 0.98 89093 21828 4 2144.213288 537.0596 Probable ATP-dependent RNA helicase DDX41 OS=Homo sapiens OX=9606 GN=DDX41 PE=1 SV=2 9.76 3378 - 412664 - - - 1.824 - 3.35 0.535 - 268.7 1 2 0 0.0039 20 0 0 0 1.19E+07 1.21E+07 - - - 4.2857 0.9998 221125_WJC_METTL3_EV_vs_WT_F06.21831.21831.4 3.36E-06 16/126 K.EK[136.11]DSFTAVVITGVQPEHIQYLK[136.11].N sp|A6NHR9|SMHD1_HUMAN 1 2517.345 2.12 89095 21831 4 2517.347253 630.3435 Structural maintenance of chromosomes flexible hinge domain-containing protein 1 OS=Homo sapiens OX=9606 GN=SMCHD1 PE=1 SV=2 5.45 3378.3 - 618075 - - - 0.899 - 2.86 0.46 - 125.8 1 2 1 0.0023 22 0 0 0 1.63E+07 7.68E+06 - - - 3.573 0.9999 221125_WJC_METTL3_EV_vs_WT_F06.21838.21838.3 4.82E-06 18/72 K.ETVTQLQNIIEANSQHYQK[136.11].N "sp|Q8IWJ2|GCC2_HUMAN,tr|B8ZZA5|B8ZZA5_HUMAN,tr|B8ZZW2|B8ZZW2_HUMAN" 3 2251.1324 2.12 89101 21838 3 2251.139009 751.3848 GRIP and coiled-coil domain-containing protein 2 OS=Homo sapiens OX=9606 GN=GCC2 PE=1 SV=4 5.4 3379.1 - 551238 - - - 2.9248 - 3.771 0.453 - 462.5 1 2 0 0.0066 19 0 0 0 1.18E+07 5.58E+06 - - - 6.8497 0.9994 221125_WJC_METTL3_EV_vs_WT_F06.21840.21840.3 0.00104 13/88 R.SPTEQEEPDPANLEVDHDFFQDK[136.11].V sp|Q96CU9|FXRD1_HUMAN 1 2694.1813 1.3 89103 21840 3 2695.186919 899.0677 FAD-dependent oxidoreductase domain-containing protein 1 OS=Homo sapiens OX=9606 GN=FOXRED1 PE=1 SV=2 3.84 3379.4 - 302655 - - - 373.2614 - 3.064 0.558 - 147.6 1 2 0 1.0056 23 0 0 0 1.25E+07 9.64E+06 - - - 7.1094 0.9997 221125_WJC_METTL3_EV_vs_WT_F06.21842.21842.3 4.62E-08 10/100 K.TFPTVNPSTGEVIC[160.03]QVAEGDKEDVDK.A "sp|P05091|ALDH2_HUMAN,tr|F8VP50|F8VP50_HUMAN" 2 2834.328 -1 89105 21842 3 2834.327708 945.7833 "Aldehyde dehydrogenase, mitochondrial OS=Homo sapiens OX=9606 GN=ALDH2 PE=1 SV=2" 4.02 3379.6 - 186894 - - - -0.1101 - 2.379 0.461 - 55.1 1 2 1 -0.0003 26 0 0 0 0.00E+00 0.00E+00 - - - 5.6735 0.9999 221125_WJC_METTL3_EV_vs_WT_F06.21846.21846.3 3.77E-06 20/72 K.ETVTQLQNIIEANSQHYQK.N "sp|Q8IWJ2|GCC2_HUMAN,tr|B8ZZA5|B8ZZA5_HUMAN,tr|B8ZZW2|B8ZZW2_HUMAN" 3 2243.1182 2.05 89107 21846 3 2243.125107 748.7134 GRIP and coiled-coil domain-containing protein 2 OS=Homo sapiens OX=9606 GN=GCC2 PE=1 SV=4 5.4 3380.2 - 974998 - - - 3.0681 - 3.362 0.46 - 586.6 1 2 0 0.0069 19 0 0 0 1.14E+07 5.58E+06 - - - 6.6456 0.9999 221125_WJC_METTL3_EV_vs_WT_F06.21849.21849.3 9.42E-07 19/84 R.EKVGEQAQVVIIDMNDPSNPIR.R "sp|Q00610|CLH1_HUMAN,tr|J3KSQ2|J3KSQ2_HUMAN,tr|J3KS13|J3KS13_HUMAN,tr|J3QL20|J3QL20_HUMAN,tr|A0A087WVQ6|A0A087WVQ6_HUMAN" 5 2451.2428 1.35 89110 21849 3 2451.24176 818.0882 Clathrin heavy chain 1 OS=Homo sapiens OX=9606 GN=CLTC PE=1 SV=5 4.32 3380.6 - 628204 - - - -0.4133 - 3.617 0.551 - 255.7 1 2 1 -0.001 22 0 0 0 1.09E+07 8.10E+06 - - - 7.7309 0.9864 221125_WJC_METTL3_EV_vs_WT_F06.21852.21852.2 1.32E-08 13/38 L.AISTPDAPATQDGVESLLQK[136.11].F "sp|Q86U44|MTA70_HUMAN,tr|B4E349|B4E349_HUMAN,tr|F5H6D8|F5H6D8_HUMAN,tr|H0YFV6|H0YFV6_HUMAN,tr|B4DTN4|B4DTN4_HUMAN" 5 2048.0517 0.001 89113 21852 2 2048.046926 1025.0331 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 4.03 3380.9 - 341002 - - - -2.3383 - 2.696 0.567 - 328.5 1 1 0 -0.0048 20 0 0 0 0.00E+00 9.94E+06 - - - 5.6657 1 221125_WJC_METTL3_EV_vs_WT_F06.21859.21859.3 1.53E-05 22/68 R.DVQIGDIVTVGEC[160.03]R[166.11]PLSK[136.11].T "sp|P62280|RS11_HUMAN,tr|M0R1H5|M0R1H5_HUMAN" 2 2003.0476 1.02 89118 21859 3 2003.052057 668.6898 40S ribosomal protein S11 OS=Homo sapiens OX=9606 GN=RPS11 PE=1 SV=3 4.56 3381.9 - 3.26E+06 - - - 2.2021 - 3.842 0.532 - 532.1 1 2 0 0.0044 18 0 0 0 3.53E+07 3.48E+07 - - - 7.8217 1 221125_WJC_METTL3_EV_vs_WT_F06.21860.21860.4 2.05E-09 34/162 K.AIGSSPLGSGEGLLGLSPGPNGHSHLLK[136.11].V "sp|Q8IY67|RAVR1_HUMAN,tr|K7EQG2|K7EQG2_HUMAN,tr|E9PAU2|E9PAU2_HUMAN,tr|A0A087WZ13|A0A087WZ13_HUMAN" 4 2659.4173 1.04 89119 21860 4 2659.424599 665.8616 Ribonucleoprotein PTB-binding 1 OS=Homo sapiens OX=9606 GN=RAVER1 PE=1 SV=1 6.96 3382 - 2.59E+06 - - - 2.7393 - 5.398 0.659 - 500.3 1 2 0 0.0073 28 0 0 0 7.37E+07 7.07E+07 - - - 5.4834 0.9999 221125_WJC_METTL3_EV_vs_WT_F06.21861.21861.4 1.18E-12 33/162 K.AIGSSPLGSGEGLLGLSPGPNGHSHLLK.V "sp|Q8IY67|RAVR1_HUMAN,tr|K7EQG2|K7EQG2_HUMAN,tr|E9PAU2|E9PAU2_HUMAN,tr|A0A087WZ13|A0A087WZ13_HUMAN" 4 2651.4031 1.04 89120 21861 4 2651.412265 663.8581 Ribonucleoprotein PTB-binding 1 OS=Homo sapiens OX=9606 GN=RAVER1 PE=1 SV=1 6.96 3382.1 - 3.26E+06 - - - 3.4514 - 4.314 0.544 - 479.7 1 2 0 0.0092 28 0 0 0 7.41E+07 7.09E+07 - - - 4.4123 0.9988 221125_WJC_METTL3_EV_vs_WT_F06.21862.21862.3 0.000245 13/48 K.ESQAKDVIEEYFK.C sp|P25398|RS12_HUMAN 1 1584.7672 1.81 89121 21862 3 1584.770489 529.263 40S ribosomal protein S12 OS=Homo sapiens OX=9606 GN=RPS12 PE=1 SV=3 4.41 3382.2 - 769097 - - - 2.1044 - 2.231 0.384 - 290.7 1 2 1 0.0033 13 0 0 0 1.42E+07 7.85E+06 - - - 4.996 0.9898 221125_WJC_METTL3_EV_vs_WT_F06.21865.21865.3 0.0331 Nov-48 K.ESQAK[136.11]DVIEEYFK[136.11].C sp|P25398|RS12_HUMAN 1 1600.7956 1.82 89124 21865 3 1600.797042 534.6058 40S ribosomal protein S12 OS=Homo sapiens OX=9606 GN=RPS12 PE=1 SV=3 4.41 3382.6 - 432485 - - - 0.9295 - 1.767 0.244 - 61 1 2 1 0.0015 13 0 0 0 1.44E+07 7.92E+06 - - - 2.8034 1 221125_WJC_METTL3_EV_vs_WT_F06.21867.21867.4 5.45E-07 Dec-78 K.GHPFFEGVDWEHIR.E sp|Q9Y2H1|ST38L_HUMAN 1 1724.8059 4.46 89126 21867 4 1724.807295 432.2088 Serine\threonine-protein kinase 38-like OS=Homo sapiens OX=9606 GN=STK38L PE=1 SV=3 5.27 3382.8 - 183445 - - - 0.7862 - 2.43 0.571 - 116.3 1 2 0 0.0014 14 0 0 0 8.36E+06 1.88E+06 - - - 4.5188 1 221125_WJC_METTL3_EV_vs_WT_F06.21872.21872.3 4.27E-08 20/76 R.KAC[160.03]GDSTLTQITAGLDPVGR.L "sp|P62879|GBB2_HUMAN,tr|C9JZN1|C9JZN1_HUMAN,tr|C9JIS1|C9JIS1_HUMAN,tr|C9JXA5|C9JXA5_HUMAN" 4 2059.0368 0.79 89129 21872 3 2059.040992 687.3529 Guanine nucleotide-binding protein G(I)\G(S)\G(T) subunit beta-2 OS=Homo sapiens OX=9606 GN=GNB2 PE=1 SV=3 5.95 3383.4 - 1.30E+06 - - - 2.034 - 3.389 0.604 - 342 1 2 0 0.0042 20 0 0 0 1.66E+07 2.09E+07 - - - 8.2339 0.9999 221125_WJC_METTL3_EV_vs_WT_F06.21876.21876.3 6.15E-07 13/72 R.MDSFDEDLARPSGLLAQER.K "sp|Q9Y2W1|TR150_HUMAN,tr|A0A3B3ITZ9|A0A3B3ITZ9_HUMAN" 2 2149.011 2.97 89133 21876 3 2149.016731 717.3443 Thyroid hormone receptor-associated protein 3 OS=Homo sapiens OX=9606 GN=THRAP3 PE=1 SV=2 4.1 3383.9 - 373205 - - - 2.6747 - 2.738 0.518 - 216.1 1 2 0 0.0057 19 0 0 0 1.37E+08 4.62E+07 - - - 6.7882 1 221125_WJC_METTL3_EV_vs_WT_F06.21882.21882.3 7.83E-06 21/76 R.K[136.11]AC[160.03]GDSTLTQITAGLDPVGR[166.11].L "sp|P62879|GBB2_HUMAN,tr|C9JZN1|C9JZN1_HUMAN,tr|C9JIS1|C9JIS1_HUMAN,tr|C9JXA5|C9JXA5_HUMAN" 4 2077.0593 0.79 89137 21882 3 2077.062116 693.3604 Guanine nucleotide-binding protein G(I)\G(S)\G(T) subunit beta-2 OS=Homo sapiens OX=9606 GN=GNB2 PE=1 SV=3 5.95 3384.7 - 1.35E+06 - - - 1.3683 - 3.259 0.564 - 399.1 1 2 0 0.0028 20 0 0 0 1.66E+07 2.09E+07 - - - 7.6934 1 221125_WJC_METTL3_EV_vs_WT_F06.21883.21883.3 3.39E-22 34/104 R.SSGDTSSEVSTVELLHLQQQQALQAAR.Q "sp|O15409|FOXP2_HUMAN,tr|Q8N6B5|Q8N6B5_HUMAN,tr|A0A0U1RQE0|A0A0U1RQE0_HUMAN,tr|A0A0U1RQR8|A0A0U1RQR8_HUMAN,tr|A8MUV4|A8MUV4_HUMAN,tr|A0A0U1RQM2|A0A0U1RQM2_HUMAN,tr|C9JQP8|C9JQP8_HUMAN,tr|A0A0U1RQY3|A0A0U1RQY3_HUMAN" 8 2882.437 5.1 89138 21883 3 2882.440165 961.8196 Forkhead box protein P2 OS=Homo sapiens OX=9606 GN=FOXP2 PE=1 SV=2 4.65 3384.8 - 1.15E+06 - - - 1.1005 - 6.098 0.722 - 1600.4 1 2 0 0.0032 27 0 0 0 6.17E+07 1.21E+07 - - - 10.7482 1 221125_WJC_METTL3_EV_vs_WT_F06.21884.21884.4 8.96E-11 32/144 R.LNQSQREELGLIEQAYDNPHEALSR.L "sp|Q6P2Q9|PRP8_HUMAN,tr|I3L0J9|I3L0J9_HUMAN" 2 2909.4268 0.67 89139 21884 4 2909.433824 728.364 Pre-mRNA-processing-splicing factor 8 OS=Homo sapiens OX=9606 GN=PRPF8 PE=1 SV=2 4.57 3384.9 - 1.12E+06 - - - 2.4269 - 5.817 0.64 - 875.1 1 2 1 0.0071 25 0 0 0 1.56E+07 2.32E+07 - - - 5.3547 0.9999 221125_WJC_METTL3_EV_vs_WT_F06.21886.21886.4 2.58E-11 22/144 R.LNQSQR[166.11]EELGLIEQAYDNPHEALSR[166.11].L "sp|Q6P2Q9|PRP8_HUMAN,tr|I3L0J9|I3L0J9_HUMAN" 2 2929.4433 0.64 89141 21886 4 2929.449645 733.3681 Pre-mRNA-processing-splicing factor 8 OS=Homo sapiens OX=9606 GN=PRPF8 PE=1 SV=2 4.57 3385.2 - 787570 - - - 2.1649 - 4.33 0.59 - 317.9 1 2 1 0.0063 25 0 0 0 1.56E+07 2.43E+07 - - - 4.8258 1 221125_WJC_METTL3_EV_vs_WT_F06.21892.21892.3 6.71E-10 30/104 K.DLLSTQPSETLASSDSFASTQPTHSWK.V sp|O75940|SPF30_HUMAN 1 2920.3727 0.79 89145 21892 3 2920.377123 974.4648 Survival of motor neuron-related-splicing factor 30 OS=Homo sapiens OX=9606 GN=SMNDC1 PE=1 SV=1 4.54 3386 - 1.36E+06 - - - 1.5279 - 4.679 0.66 - 810.5 1 2 0 0.0045 27 0 0 0 6.62E+07 8.37E+07 - - - 9.4472 1 221125_WJC_METTL3_EV_vs_WT_F06.21894.21894.3 5.59E-11 23/92 R.SGSTAVGVLISPQHTYFINC[160.03]GDSR.G "sp|P35813|PPM1A_HUMAN,tr|E9PKB5|E9PKB5_HUMAN,tr|E9PJN3|E9PJN3_HUMAN" 3 2565.2282 1.41 89147 21894 3 2565.233542 856.0833 Protein phosphatase 1A OS=Homo sapiens OX=9606 GN=PPM1A PE=1 SV=1 6.46 3386.2 - 1.26E+06 - - - 2.0879 - 4.375 0.647 - 613.9 1 2 0 0.0054 24 0 0 0 4.16E+07 2.95E+07 - - - 9.1799 1 221125_WJC_METTL3_EV_vs_WT_F06.21896.21896.3 7.03E-09 23/92 R.SGSTAVGVLISPQHTYFINC[160.03]GDSR[166.11].G "sp|P35813|PPM1A_HUMAN,tr|E9PKB5|E9PKB5_HUMAN,tr|E9PJN3|E9PJN3_HUMAN" 3 2575.2365 1.44 89149 21896 3 2575.240115 859.4194 Protein phosphatase 1A OS=Homo sapiens OX=9606 GN=PPM1A PE=1 SV=1 6.46 3386.5 - 889988 - - - 1.4208 - 4.369 0.638 - 532.7 1 2 0 0.0037 24 0 0 0 4.29E+07 2.98E+07 - - - 9.0768 0.9997 221125_WJC_METTL3_EV_vs_WT_F06.21897.21897.3 0.000125 24/108 K.AIGSSPLGSGEGLLGLSPGPNGHSHLLK[136.11].V "sp|Q8IY67|RAVR1_HUMAN,tr|K7EQG2|K7EQG2_HUMAN,tr|E9PAU2|E9PAU2_HUMAN,tr|A0A087WZ13|A0A087WZ13_HUMAN" 4 2659.4173 1.39 89150 21897 3 2659.432353 887.4797 Ribonucleoprotein PTB-binding 1 OS=Homo sapiens OX=9606 GN=RAVER1 PE=1 SV=1 6.96 3386.6 - 649920 - - - 5.655 - 4.455 0.534 - 420.8 1 2 0 0.015 28 0 0 0 7.46E+06 5.36E+06 - - - 7.9266 1 221125_WJC_METTL3_EV_vs_WT_F06.21901.21901.3 1.64E-11 21/96 K.VFNNIGADLLTGSESENKEDGLQNK.H "sp|Q6P3W7|SCYL2_HUMAN,tr|F8VSC5|F8VSC5_HUMAN,tr|A0A0U1RQQ9|A0A0U1RQQ9_HUMAN" 3 2691.2988 1.97 89152 21901 3 2691.305023 898.1069 SCY1-like protein 2 OS=Homo sapiens OX=9606 GN=SCYL2 PE=1 SV=1 4.18 3387.1 - 3.34E+06 - - - 2.3242 - 4.447 0.609 - 506.3 1 2 1 0.0063 25 0 0 0 3.98E+08 2.02E+08 - - - 8.7611 0.9999 221125_WJC_METTL3_EV_vs_WT_F06.21904.21904.4 5.11E-07 17/108 R.GLLQDDAHPTLVTYADHSK[136.11].L "sp|Q86U44|MTA70_HUMAN,tr|F5H6D8|F5H6D8_HUMAN,tr|H0YFV6|H0YFV6_HUMAN,tr|B4DTN4|B4DTN4_HUMAN" 4 2088.0367 0.01 89155 21904 4 2088.037607 523.0165 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 5.13 3387.4 - 1.25E+06 - - - 0.4186 - 3.143 0.427 - 236.7 1 2 0 0.0009 19 0 0 0 2.59E+05 3.06E+07 - - - 3.3298 1 221125_WJC_METTL3_EV_vs_WT_F06.21906.21906.4 7.36E-09 20/126 K.HYGYNSYSVSNSEKDIMAEIYK.N "sp|P07858|CATB_HUMAN,tr|A0A7I2V440|A0A7I2V440_HUMAN,tr|E9PQM1|E9PQM1_HUMAN,tr|A0A7I2V668|A0A7I2V668_HUMAN,tr|A0A7P0NGZ6|A0A7P0NGZ6_HUMAN,tr|A0A7I2YQK9|A0A7I2YQK9_HUMAN,tr|E9PHZ5|E9PHZ5_HUMAN,tr|E9PR21|E9PR21_HUMAN" 8 2597.1744 1.26 89157 21906 4 2597.170396 650.3009 Cathepsin B OS=Homo sapiens OX=9606 GN=CTSB PE=1 SV=3 5.45 3387.7 - 580225 - - - -1.549 - 3.698 0.634 - 371.2 1 2 1 -0.004 22 0 0 0 7.57E+06 6.01E+06 - - - 5.1711 0.9999 221125_WJC_METTL3_EV_vs_WT_F06.21907.21907.3 9.73E-08 20/108 R.KVVGSMPTAGSAGSVPENLNLFPEPGSK.S "sp|Q8WU79|SMAP2_HUMAN,tr|A0A087WV97|A0A087WV97_HUMAN" 2 2769.4007 2.51 89158 21907 3 2769.39245 924.1409 Stromal membrane-associated protein 2 OS=Homo sapiens OX=9606 GN=SMAP2 PE=1 SV=1 6.14 3387.8 - 459506 - - - -2.9902 - 3.134 0.497 - 283.5 1 2 0 -0.0083 28 0 0 0 7.55E+07 3.01E+07 - - - 6.7068 1 221125_WJC_METTL3_EV_vs_WT_F06.21910.21910.3 9.45E-12 21/104 R.SSGDTSSEVSTVELLHLQQQQALQAAR[166.11].Q "sp|O15409|FOXP2_HUMAN,tr|Q8N6B5|Q8N6B5_HUMAN,tr|A0A0U1RQE0|A0A0U1RQE0_HUMAN,tr|A0A0U1RQR8|A0A0U1RQR8_HUMAN,tr|A8MUV4|A8MUV4_HUMAN,tr|A0A0U1RQM2|A0A0U1RQM2_HUMAN,tr|C9JQP8|C9JQP8_HUMAN,tr|A0A0U1RQY3|A0A0U1RQY3_HUMAN" 8 2892.4453 5.1 89159 21910 3 2892.442094 965.1557 Forkhead box protein P2 OS=Homo sapiens OX=9606 GN=FOXP2 PE=1 SV=2 4.65 3388.2 - 628131 - - - -1.0956 - 4.835 0.714 - 420.5 1 2 0 -0.0032 27 0 0 0 6.17E+07 1.21E+07 - - - 10.125 1 221125_WJC_METTL3_EV_vs_WT_F06.21912.21912.3 4.09E-09 17/72 R.MDSFDEDLAR[166.11]PSGLLAQER[166.11].K "sp|Q9Y2W1|TR150_HUMAN,tr|A0A3B3ITZ9|A0A3B3ITZ9_HUMAN" 2 2169.0275 2.95 89161 21912 3 2169.023073 724.0165 Thyroid hormone receptor-associated protein 3 OS=Homo sapiens OX=9606 GN=THRAP3 PE=1 SV=2 4.1 3388.4 - 2.08E+06 - - - -2.0516 - 3.129 0.574 - 419.6 1 2 0 -0.0044 19 0 0 0 1.35E+08 4.58E+07 - - - 7.7408 0.9999 221125_WJC_METTL3_EV_vs_WT_F06.21913.21913.3 2.44E-08 19/88 K.SPLALLAQTC[160.03]SQIGKPDPPPSSK.L sp|Q9H7S9|ZN703_HUMAN 1 2391.2468 1.37 89162 21913 3 2391.252075 798.0895 Zinc finger protein 703 OS=Homo sapiens OX=9606 GN=ZNF703 PE=1 SV=1 7.92 3388.5 - 1.03E+06 - - - 2.2076 - 3.42 0.462 - 212.8 1 2 0 0.0053 23 0 0 0 3.75E+07 2.74E+07 - - - 6.5741 1 221125_WJC_METTL3_EV_vs_WT_F06.21914.21914.3 0.000228 16/108 K.AIGSSPLGSGEGLLGLSPGPNGHSHLLK.V "sp|Q8IY67|RAVR1_HUMAN,tr|K7EQG2|K7EQG2_HUMAN,tr|E9PAU2|E9PAU2_HUMAN,tr|A0A087WZ13|A0A087WZ13_HUMAN" 4 2651.4031 1.39 89163 21914 3 2651.403217 884.8083 Ribonucleoprotein PTB-binding 1 OS=Homo sapiens OX=9606 GN=RAVER1 PE=1 SV=1 6.96 3388.7 - 470496 - - - 0.0388 - 3.371 0.472 - 160.3 1 2 0 0.0001 28 0 0 0 7.46E+06 5.36E+06 - - - 6.5981 0.9958 221125_WJC_METTL3_EV_vs_WT_F06.21915.21915.4 1.12E-05 23/108 K.ISSIQSIVPALEIANAHR[166.11]K[136.11].P "sp|P10809|CH60_HUMAN,tr|A0A7I2V2X6|A0A7I2V2X6_HUMAN,tr|A0A7I2YQK6|A0A7I2YQK6_HUMAN,tr|A0A7I2V599|A0A7I2V599_HUMAN,tr|A0A7I2YQ71|A0A7I2YQ71_HUMAN,tr|A0A7I2V5M1|A0A7I2V5M1_HUMAN,tr|A0A7I2V5K3|A0A7I2V5K3_HUMAN,tr|A0A7I2V369|A0A7I2V369_HUMAN" 8 2064.181 1.18 89164 21915 4 2064.183231 517.0525 "60 kDa heat shock protein, mitochondrial OS=Homo sapiens OX=9606 GN=HSPD1 PE=1 SV=2" 8.75 3388.8 - 316595 - - - 1.06 - 3.524 0.49 - 409.6 1 1 0 0.0022 19 0 0 0 7.16E+07 6.05E+07 - - - 3.9165 1 221125_WJC_METTL3_EV_vs_WT_F06.21916.21916.4 3.82E-05 Dec-78 K.GHPFFEGVDWEHIR[166.11].E sp|Q9Y2H1|ST38L_HUMAN 1 1734.8142 4.46 89165 21916 4 1734.815016 434.7108 Serine\threonine-protein kinase 38-like OS=Homo sapiens OX=9606 GN=STK38L PE=1 SV=3 5.27 3388.9 - 189961 - - - 0.4652 - 2.16 0.539 - 115.4 1 2 0 0.0008 14 0 0 0 8.36E+06 1.88E+06 - - - 4.1975 1 221125_WJC_METTL3_EV_vs_WT_F06.21918.21918.3 6.37E-13 35/124 K.VGGTNLGAPGAFGQSPFSQPPAPPHQNTFPPR.S sp|Q96I24|FUBP3_HUMAN 1 3227.5901 2.32 89166 21918 3 3227.590246 1076.8706 Far upstream element-binding protein 3 OS=Homo sapiens OX=9606 GN=FUBP3 PE=1 SV=2 9.73 3389.1 - 4.08E+06 - - - 0.0514 - 4.939 0.64 - 747.8 1 2 0 0.0002 32 0 0 0 1.27E+08 5.47E+07 - - - 9.3498 1 221125_WJC_METTL3_EV_vs_WT_F06.21922.21922.4 9.55E-11 18/90 R.K[136.11]FDEVLVNHFC[160.03]EEFGK[136.11].K "sp|P34932|HSP74_HUMAN,tr|A0A087WTS8|A0A087WTS8_HUMAN,tr|A0A087WYC1|A0A087WYC1_HUMAN" 3 2012.9637 0.11 89169 21922 4 2012.965152 504.2482 Heat shock 70 kDa protein 4 OS=Homo sapiens OX=9606 GN=HSPA4 PE=1 SV=4 4.83 3389.6 - 758778 - - - 0.7218 - 3.382 0.644 - 450.6 1 2 0 0.0015 16 0 0 0 9.67E+05 9.08E+06 - - - 5.2602 0.9999 221125_WJC_METTL3_EV_vs_WT_F06.21923.21923.4 1.85E-05 17/156 K.LIESVSQPLENHGAPIIGHISESLSTK.S "tr|A0A0G2JNB1|A0A0G2JNB1_HUMAN,tr|A0A0G2JNT7|A0A0G2JNT7_HUMAN,tr|A0A0G2JQF4|A0A0G2JQF4_HUMAN,tr|A0A0G2JQF5|A0A0G2JQF5_HUMAN,tr|A0A1W2PPV8|A0A1W2PPV8_HUMAN,tr|A0A3B3IT55|A0A3B3IT55_HUMAN,tr|I3L233|I3L233_HUMAN,tr|A0A0J9YVS1|A0A0J9YVS1_HUMAN,tr|A0A1W2PRB5|A0A1W2PRB5_HUMAN,tr|A0A1W2PQT4|A0A1W2PQT4_HUMAN" 10 2855.5029 1.86 89170 21923 4 2855.511822 714.883 KAT8 regulatory NSL complex subunit 1 OS=Homo sapiens OX=9606 GN=KANSL1 PE=1 SV=1 5.33 3389.8 - 488081 - - - 3.1287 - 3.53 0.529 - 96.4 1 2 0 0.0089 27 0 0 0 4.82E+06 2.59E+06 - - - 4.2226 0.9716 221125_WJC_METTL3_EV_vs_WT_F06.21926.21926.3 7.27E-07 17/100 R.AEETSSPVIGELWSPDQTAEASHVSR.Y sp|Q86XL3|ANKL2_HUMAN 1 2782.3046 3.15 89171 21926 3 2783.323914 928.4421 Ankyrin repeat and LEM domain-containing protein 2 OS=Homo sapiens OX=9606 GN=ANKLE2 PE=1 SV=4 4.25 3390.1 - 878284 - - - 366.3625 - 2.963 0.494 - 179.7 1 2 0 1.0193 26 0 0 0 2.40E+07 7.62E+06 - - - 6.2642 0.9986 221125_WJC_METTL3_EV_vs_WT_F06.21927.21927.3 5.39E-07 18/88 K.SPLALLAQTC[160.03]SQIGK[136.11]PDPSPSSK[136.11].L sp|Q96F45|ZN503_HUMAN 1 2397.2545 1.81 89172 21927 3 2398.25114 800.0921 Zinc finger protein 503 OS=Homo sapiens OX=9606 GN=ZNF503 PE=1 SV=1 7.92 3390.2 - 1.30E+06 - - - 415.7585 - 3.77 0.551 - 218.6 1 2 0 0.9967 23 0 0 0 4.71E+07 2.60E+07 - - - 7.5203 0.9995 221125_WJC_METTL3_EV_vs_WT_F06.21928.21928.4 7.88E-06 16/132 K.SPLALLAQTC[160.03]SQIGKPDPPPSSK.L sp|Q9H7S9|ZN703_HUMAN 1 2391.2468 1.65 89173 21928 4 2391.25658 598.819 Zinc finger protein 703 OS=Homo sapiens OX=9606 GN=ZNF703 PE=1 SV=1 7.92 3390.4 - 501373 - - - 4.0916 - 3.415 0.438 - 98.7 1 2 0 0.0098 23 0 0 0 5.82E+06 3.52E+06 - - - 3.4336 1 221125_WJC_METTL3_EV_vs_WT_F06.21930.21930.4 3.60E-09 25/186 K.VGGTNLGAPGAFGQSPFSQPPAPPHQNTFPPR.S sp|Q96I24|FUBP3_HUMAN 1 3227.5901 2.55 89174 21930 4 3227.594518 807.9048 Far upstream element-binding protein 3 OS=Homo sapiens OX=9606 GN=FUBP3 PE=1 SV=2 9.73 3390.6 - 7.79E+06 - - - 1.375 - 4.308 0.548 - 182.6 1 2 0 0.0044 32 0 0 0 1.37E+08 5.38E+07 - - - 4.4355 0.9999 221125_WJC_METTL3_EV_vs_WT_F06.21931.21931.4 0.000118 16/102 R.SPSELFAQHIVTIVHHVK.E "sp|Q9Y2W1|TR150_HUMAN,tr|A0A3B3ITZ9|A0A3B3ITZ9_HUMAN" 2 2041.1109 4.56 89175 21931 4 2041.111608 511.285 Thyroid hormone receptor-associated protein 3 OS=Homo sapiens OX=9606 GN=THRAP3 PE=1 SV=2 6.78 3390.8 - 876760 - - - 0.3493 - 2.913 0.421 - 187.9 1 2 0 0.0007 18 0 0 0 2.40E+07 5.27E+06 - - - 3.2564 1 221125_WJC_METTL3_EV_vs_WT_F06.21933.21933.4 1.85E-09 11/150 R.SIMEEC[160.03]GGVHIHFPVEGSGSDTVVIR.G "sp|Q00341|VIGLN_HUMAN,tr|A0A024R4E5|A0A024R4E5_HUMAN,tr|H7BZC3|H7BZC3_HUMAN,tr|H7C2D1|H7C2D1_HUMAN,tr|H0Y394|H0Y394_HUMAN" 5 2811.332 0.64 89177 21933 4 2811.333077 703.8403 Vigilin OS=Homo sapiens OX=9606 GN=HDLBP PE=1 SV=2 4.8 3391 - 917661 - - - 0.3831 - 2.611 0.625 - 91.8 1 2 0 0.0011 26 0 0 0 6.69E+06 1.04E+07 - - - 4.9684 1 221125_WJC_METTL3_EV_vs_WT_F06.21939.21939.3 4.81E-06 15/68 K.TVTNAVVTVPAYFNDSQR[166.11].Q "sp|P11142|HSP7C_HUMAN,tr|E9PQQ4|E9PQQ4_HUMAN,tr|E9PN89|E9PN89_HUMAN,tr|E9PLF4|E9PLF4_HUMAN,tr|E9PI65|E9PI65_HUMAN,tr|E9PK54|E9PK54_HUMAN,tr|E9PQK7|E9PQK7_HUMAN" 7 1990.9988 0.12 89181 21939 3 1990.996164 664.6735 Heat shock cognate 71 kDa protein OS=Homo sapiens OX=9606 GN=HSPA8 PE=1 SV=1 5.5 3391.6 - 2.18E+06 - - - -1.3114 - 3.038 0.564 - 319.8 1 2 0 -0.0026 18 0 0 0 1.31E+07 1.10E+08 - - - 7.5943 1 221125_WJC_METTL3_EV_vs_WT_F06.21941.21941.3 8.76E-17 27/88 K.SPTMEQAVQTASAHLPAPAAVGR[166.11].R sp|Q8ND56|LS14A_HUMAN 1 2299.1618 1.36 89183 21941 3 2299.164884 767.3946 Protein LSM14 homolog A OS=Homo sapiens OX=9606 GN=LSM14A PE=1 SV=3 6.47 3391.8 - 1.79E+06 - - - 1.3266 - 4.524 0.686 - 428.4 1 2 0 0.003 23 0 0 0 4.05E+07 2.97E+07 - - - 9.7283 1 221125_WJC_METTL3_EV_vs_WT_F06.21943.21943.4 5.97E-10 22/138 R.FSTFAGSITGPLYTHRPPITISSK.L "sp|P07197|NFM_HUMAN,tr|E7ESP9|E7ESP9_HUMAN,tr|E7EMV2|E7EMV2_HUMAN" 3 2577.3591 6.02 89185 21943 4 2577.364538 645.3471 Neurofilament medium polypeptide OS=Homo sapiens OX=9606 GN=NEFM PE=1 SV=3 9.99 3392.1 - 642959 - - - 2.1006 - 4.307 0.634 - 352.5 1 2 0 0.0054 24 0 0 0 1.41E+07 2.34E+06 - - - 5.2115 0.9998 221125_WJC_METTL3_EV_vs_WT_F06.21944.21944.4 0.000293 21/120 R.WTTSQLLQHPFVTVDSNKPIR.E sp|Q9H2G2|SLK_HUMAN 1 2466.3019 0.39 89186 21944 4 2466.307446 617.5828 STE20-like serine\threonine-protein kinase OS=Homo sapiens OX=9606 GN=SLK PE=1 SV=1 8.75 3392.2 - 473303 - - - 2.2313 - 3.821 0.397 - 325.5 1 2 0 0.0055 21 0 0 0 5.85E+06 1.48E+07 - - - 3.1232 1 221125_WJC_METTL3_EV_vs_WT_F06.21948.21948.4 4.49E-07 34/186 K.VGGTNLGAPGAFGQSPFSQPPAPPHQNTFPPR[166.11].S sp|Q96I24|FUBP3_HUMAN 1 3237.5984 2.55 89188 21948 4 3237.601518 810.4069 Far upstream element-binding protein 3 OS=Homo sapiens OX=9606 GN=FUBP3 PE=1 SV=2 9.73 3392.7 - 2.11E+06 - - - 0.9785 - 4.761 0.551 - 420.5 1 2 0 0.0032 32 0 0 0 1.37E+08 5.38E+07 - - - 4.4922 0.9898 221125_WJC_METTL3_EV_vs_WT_F06.21949.21949.4 5.67E-06 29/108 K.ISSIQSIVPALEIANAHRK.P "sp|P10809|CH60_HUMAN,tr|A0A7I2V2X6|A0A7I2V2X6_HUMAN,tr|A0A7I2YQK6|A0A7I2YQK6_HUMAN,tr|A0A7I2V599|A0A7I2V599_HUMAN,tr|A0A7I2YQ71|A0A7I2YQ71_HUMAN,tr|A0A7I2V5M1|A0A7I2V5M1_HUMAN,tr|A0A7I2V5K3|A0A7I2V5K3_HUMAN,tr|A0A7I2V369|A0A7I2V369_HUMAN" 8 2046.1586 1.18 89189 21949 4 2046.164148 512.5469 "60 kDa heat shock protein, mitochondrial OS=Homo sapiens OX=9606 GN=HSPD1 PE=1 SV=2" 8.75 3392.8 - 878708 - - - 2.7246 - 4.165 0.488 - 771.2 1 1 0 0.0056 19 0 0 0 7.16E+07 6.05E+07 - - - 3.9546 1 221125_WJC_METTL3_EV_vs_WT_F06.21950.21950.3 1.61E-13 24/92 K.NPSTNFQEPVQPLTQQQVAQMQLK[136.11].Y "sp|P19623|SPEE_HUMAN,tr|K7EL89|K7EL89_HUMAN" 2 2761.3949 0.41 89190 21950 3 2761.39991 921.4722 Spermidine synthase OS=Homo sapiens OX=9606 GN=SRM PE=1 SV=1 6 3393 - 748040 - - - 1.8273 - 4.302 0.685 - 817.7 1 2 0 0.005 24 0 0 0 5.67E+06 1.37E+07 - - - 9.5645 0.9834 221125_WJC_METTL3_EV_vs_WT_F06.21951.21951.3 2.83E-05 17/80 S.ALSSASTSSHNLQSIFNIGSR[166.11].G "sp|P43243|MATR3_HUMAN,tr|A8MXP9|A8MXP9_HUMAN,tr|D6R991|D6R991_HUMAN,tr|D6REK4|D6REK4_HUMAN,tr|A0A0R4J2E8|A0A0R4J2E8_HUMAN,tr|D6RCM3|D6RCM3_HUMAN,tr|D6R8Z5|D6R8Z5_HUMAN,tr|D6REM6|D6REM6_HUMAN" 8 2186.0955 0.83 89191 21951 3 2186.102227 729.7058 Matrin-3 OS=Homo sapiens OX=9606 GN=MATR3 PE=1 SV=2 9.8 3393.1 - 615016 - - - 3.0639 - 2.858 0.458 - 284 1 1 0 0.0067 21 0 0 0 1.02E+07 1.23E+07 - - - 6.162 1 221125_WJC_METTL3_EV_vs_WT_F06.21954.21954.2 1.76E-08 21/34 K.TVTNAVVTVPAYFNDSQR[166.11].Q "sp|P11142|HSP7C_HUMAN,tr|E9PQQ4|E9PQQ4_HUMAN,tr|E9PN89|E9PN89_HUMAN,tr|E9PLF4|E9PLF4_HUMAN,tr|E9PI65|E9PI65_HUMAN,tr|E9PK54|E9PK54_HUMAN,tr|E9PQK7|E9PQK7_HUMAN" 7 1990.9988 0.22 89194 21954 2 1990.999007 996.5067 Heat shock cognate 71 kDa protein OS=Homo sapiens OX=9606 GN=HSPA8 PE=1 SV=1 5.5 3393.5 - 521934 - - - 0.1165 - 3.295 0.593 - 980.2 1 2 0 0.0002 18 0 0 0 8.46E+06 3.89E+07 - - - 6.3524 1 221125_WJC_METTL3_EV_vs_WT_F06.21956.21956.3 5.49E-12 18/92 K.NPSTNFQEPVQPLTQQQVAQMQLK.Y "sp|P19623|SPEE_HUMAN,tr|K7EL89|K7EL89_HUMAN" 2 2753.3807 0.4 89196 21956 3 2753.390358 918.8008 Spermidine synthase OS=Homo sapiens OX=9606 GN=SRM PE=1 SV=1 6 3393.8 - 391375 - - - 3.5208 - 3.655 0.666 - 318.2 1 2 0 0.0097 24 0 0 0 5.53E+06 1.37E+07 - - - 8.9729 0.9999 221125_WJC_METTL3_EV_vs_WT_F06.21957.21957.3 0.00677 17/60 K.KDC[160.03]EVVMMIGLPGAGK.T "sp|Q00839|HNRPU_HUMAN,tr|A0A1W2PQL0|A0A1W2PQL0_HUMAN,tr|A0A1W2PPL4|A0A1W2PPL4_HUMAN,tr|A0A1W2PQ74|A0A1W2PQ74_HUMAN,tr|Q5RI18|Q5RI18_HUMAN,tr|A0A1W2PP35|A0A1W2PP35_HUMAN,tr|A0A1W2PPS1|A0A1W2PPS1_HUMAN,tr|A0A1W2PRZ7|A0A1W2PRZ7_HUMAN,tr|A0A1W2PPH7|A0A1W2PPH7_HUMAN,tr|A0A1W2PQD4|A0A1W2PQD4_HUMAN,tr|A0A1W2PP34|A0A1W2PP34_HUMAN,tr|A0A1X7SBS1|A0A1X7SBS1_HUMAN" 12 1703.8409 0.84 89197 21957 3 1703.84605 568.9542 Heterogeneous nuclear ribonucleoprotein U OS=Homo sapiens OX=9606 GN=HNRNPU PE=1 SV=6 6.06 3393.9 - 367474 - - - 3.0402 - 3.006 0.486 - 282.8 1 2 0 0.0052 16 0 0 0 2.68E+07 3.20E+07 - - - 6.781 1 221125_WJC_METTL3_EV_vs_WT_F06.21959.21959.3 7.65E-09 36/124 K.VGGTNLGAPGAFGQSPFSQPPAPPHQNTFPPR[166.11].S sp|Q96I24|FUBP3_HUMAN 1 3237.5984 2.32 89198 21959 3 3237.601423 1080.2067 Far upstream element-binding protein 3 OS=Homo sapiens OX=9606 GN=FUBP3 PE=1 SV=2 9.73 3394.1 - 1.65E+06 - - - 0.9492 - 4.731 0.633 - 881.9 1 2 0 0.0031 32 0 0 0 1.27E+08 5.47E+07 - - - 9.172 0.9999 221125_WJC_METTL3_EV_vs_WT_F06.21961.21961.3 2.36E-12 21/96 K.VFNNIGADLLTGSESENK[136.11]EDGLQNK[136.11].H "sp|Q6P3W7|SCYL2_HUMAN,tr|F8VSC5|F8VSC5_HUMAN,tr|A0A0U1RQQ9|A0A0U1RQQ9_HUMAN" 3 2707.3272 1.96 89199 21961 3 2707.326964 903.4497 SCY1-like protein 2 OS=Homo sapiens OX=9606 GN=SCYL2 PE=1 SV=1 4.18 3394.3 - 1.21E+07 - - - -0.0754 - 4.181 0.541 - 468.8 1 2 1 -0.0002 25 0 0 0 3.97E+08 2.02E+08 - - - 7.8627 0.9999 221125_WJC_METTL3_EV_vs_WT_F06.21962.21962.3 6.09E-11 22/80 R.EEAENTLQSFRQDVDNASLAR.L "sp|P08670|VIME_HUMAN,tr|B0YJC5|B0YJC5_HUMAN,tr|B0YJC4|B0YJC4_HUMAN" 3 2392.1255 1.98 89200 21962 3 2392.128768 798.3824 Vimentin OS=Homo sapiens OX=9606 GN=VIM PE=1 SV=4 4.18 3394.4 - 6.41E+06 - - - 1.3682 - 3.383 0.608 - 643.6 1 2 1 0.0033 21 0 0 0 1.12E+08 5.63E+07 - - - 8.2396 0.9999 221125_WJC_METTL3_EV_vs_WT_F06.21963.21963.3 0.000161 20/80 R.EEAENTLQSFR[166.11]QDVDNASLAR[166.11].L "sp|P08670|VIME_HUMAN,tr|B0YJC5|B0YJC5_HUMAN,tr|B0YJC4|B0YJC4_HUMAN" 3 2412.142 1.98 89201 21963 3 2412.144037 805.0546 Vimentin OS=Homo sapiens OX=9606 GN=VIM PE=1 SV=4 4.18 3394.4 - 4.29E+06 - - - 0.83 - 3.609 0.548 - 636.6 1 2 1 0.002 21 0 0 0 1.12E+08 5.63E+07 - - - 7.7261 1 221125_WJC_METTL3_EV_vs_WT_F06.21967.21967.3 1.21E-10 23/88 R.DALPEYSTFDVNMKPVVQEPNQK.V "sp|P49406|RM19_HUMAN,tr|S4R455|S4R455_HUMAN,tr|S4R3W9|S4R3W9_HUMAN" 3 2648.2792 1.34 89205 21967 3 2648.287626 883.767 "39S ribosomal protein L19, mitochondrial OS=Homo sapiens OX=9606 GN=MRPL19 PE=1 SV=2" 4.32 3394.9 - 891052 - - - 3.1745 - 3.782 0.622 - 421.1 1 2 0 0.0084 23 0 0 0 1.69E+07 1.26E+07 - - - 8.5931 1 221125_WJC_METTL3_EV_vs_WT_F06.21969.21969.3 2.86E-05 17/60 K.K[136.11]DC[160.03]EVVMMIGLPGAGK[136.11].T "sp|Q00839|HNRPU_HUMAN,tr|A0A1W2PQL0|A0A1W2PQL0_HUMAN,tr|A0A1W2PPL4|A0A1W2PPL4_HUMAN,tr|A0A1W2PQ74|A0A1W2PQ74_HUMAN,tr|Q5RI18|Q5RI18_HUMAN,tr|A0A1W2PP35|A0A1W2PP35_HUMAN,tr|A0A1W2PPS1|A0A1W2PPS1_HUMAN,tr|A0A1W2PRZ7|A0A1W2PRZ7_HUMAN,tr|A0A1W2PPH7|A0A1W2PPH7_HUMAN,tr|A0A1W2PQD4|A0A1W2PQD4_HUMAN,tr|A0A1W2PP34|A0A1W2PP34_HUMAN,tr|A0A1X7SBS1|A0A1X7SBS1_HUMAN" 12 1719.8693 0.94 89207 21969 3 1719.871641 574.297 Heterogeneous nuclear ribonucleoprotein U OS=Homo sapiens OX=9606 GN=HNRNPU PE=1 SV=6 6.06 3395.1 - 776195 - - - 1.3786 - 3.11 0.544 - 362.3 1 2 0 0.0024 16 0 0 0 2.65E+07 2.80E+07 - - - 7.5157 1 221125_WJC_METTL3_EV_vs_WT_F06.21974.21974.3 9.52E-14 25/88 R.DALPEYSTFDVNMK[136.11]PVVQEPNQK[136.11].V "sp|P49406|RM19_HUMAN,tr|S4R455|S4R455_HUMAN,tr|S4R3W9|S4R3W9_HUMAN" 3 2664.3076 1.34 89210 21974 3 2664.314149 889.1098 "39S ribosomal protein L19, mitochondrial OS=Homo sapiens OX=9606 GN=MRPL19 PE=1 SV=2" 4.32 3395.8 - 1.11E+06 - - - 2.4509 - 4.221 0.685 - 609.3 1 2 0 0.0065 23 0 0 0 1.69E+07 1.26E+07 - - - 9.5536 0.9999 221125_WJC_METTL3_EV_vs_WT_F06.21975.21975.3 1.21E-09 15/44 R.AR[166.11]FEELC[160.03]SDLFR[166.11].S "sp|P48741|HSP77_HUMAN,sp|P0DMV8|HS71A_HUMAN,sp|P0DMV9|HS71B_HUMAN,sp|P17066|HSP76_HUMAN,tr|V9GZ37|V9GZ37_HUMAN,tr|A0A0G2JIW1|A0A0G2JIW1_HUMAN" 6 1561.7462 0.07 89211 21975 3 1561.749019 521.5893 Putative heat shock 70 kDa protein 7 OS=Homo sapiens OX=9606 GN=HSPA7 PE=5 SV=2 4.68 3395.9 - 2.11E+06 - - - 1.8031 - 2.981 0.503 - 430.1 1 2 1 0.0028 12 0 0 0 1.62E+06 2.41E+07 - - - 7.1748 1 221125_WJC_METTL3_EV_vs_WT_F06.21976.21976.3 1.22E-09 31/88 K.SPTMEQAVQTASAHLPAPAAVGR.R sp|Q8ND56|LS14A_HUMAN 1 2289.1536 1.64 89212 21976 3 2289.161433 764.0585 Protein LSM14 homolog A OS=Homo sapiens OX=9606 GN=LSM14A PE=1 SV=3 6.47 3396 - 2.00E+06 - - - 3.4375 - 4.89 0.623 - 523 1 2 0 0.0079 23 0 0 0 3.26E+07 1.99E+07 - - - 9.2071 0.9999 221125_WJC_METTL3_EV_vs_WT_F06.21979.21979.4 3.88E-10 23/132 K.DTEQYER[166.11]EDFLIK[136.11]PSDNLIVC[160.03]GR[166.11].A "sp|Q13610|PWP1_HUMAN,tr|B4DJV5|B4DJV5_HUMAN,tr|F8VZ56|F8VZ56_HUMAN" 3 2824.3696 1.24 89215 21979 4 2824.370191 707.0997 Periodic tryptophan protein 1 homolog OS=Homo sapiens OX=9606 GN=PWP1 PE=1 SV=1 4.3 3396.3 - 843304 - - - 0.2096 - 3.929 0.524 - 270.4 1 2 1 0.0006 23 0 0 0 1.68E+07 1.35E+07 - - - 4.2301 0.9999 221125_WJC_METTL3_EV_vs_WT_F06.21980.21980.4 8.14E-13 25/132 K.DTEQYEREDFLIKPSDNLIVC[160.03]GR.A "sp|Q13610|PWP1_HUMAN,tr|B4DJV5|B4DJV5_HUMAN,tr|F8VZ56|F8VZ56_HUMAN" 3 2796.3389 1.24 89216 21980 4 2796.346552 700.092 Periodic tryptophan protein 1 homolog OS=Homo sapiens OX=9606 GN=PWP1 PE=1 SV=1 4.3 3396.5 - 793258 - - - 2.7511 - 4.088 0.593 - 276.5 1 2 1 0.0077 23 0 0 0 1.68E+07 1.35E+07 - - - 4.8415 0.9999 221125_WJC_METTL3_EV_vs_WT_F06.21982.21982.4 3.40E-11 24/114 K.SDK[136.11]DLETQVIQLNEQVHSLK[136.11].L sp|Q15555|MARE2_HUMAN 1 2339.2304 1.03 89218 21982 4 2339.233347 585.8149 Microtubule-associated protein RP\EB family member 2 OS=Homo sapiens OX=9606 GN=MAPRE2 PE=1 SV=1 4.75 3396.7 - 724527 - - - 1.2795 - 4.341 0.572 - 708.1 1 2 1 0.003 20 0 0 0 1.59E+07 1.55E+07 - - - 4.6947 0.997 221125_WJC_METTL3_EV_vs_WT_F06.21983.21983.4 0.0103 15/120 R.EEAENTLQSFR[166.11]QDVDNASLAR[166.11].L "sp|P08670|VIME_HUMAN,tr|B0YJC5|B0YJC5_HUMAN,tr|B0YJC4|B0YJC4_HUMAN" 3 2412.142 2.18 89219 21983 4 2412.147227 604.0428 Vimentin OS=Homo sapiens OX=9606 GN=VIM PE=1 SV=4 4.18 3396.9 - 475541 - - - 2.1524 - 2.244 0.337 - 132.1 1 2 1 0.0052 21 0 0 0 4.93E+06 2.26E+06 - - - 2.4251 1 221125_WJC_METTL3_EV_vs_WT_F06.21988.21988.3 5.38E-05 20/80 K.KGPDGLALPNNYC[160.03]DFC[160.03]LGDSK.L "sp|Q92785|REQU_HUMAN,tr|J3KMZ8|J3KMZ8_HUMAN" 2 2340.0515 1.56 89222 21988 3 2340.046758 781.0244 Zinc finger protein ubi-d4 OS=Homo sapiens OX=9606 GN=DPF2 PE=1 SV=2 4.43 3397.4 - 2.25E+06 - - - -2.0128 - 3.751 0.653 - 433.8 1 2 0 -0.0047 21 0 0 0 6.69E+07 4.29E+07 - - - 8.9885 1 221125_WJC_METTL3_EV_vs_WT_F06.21989.21989.3 4.39E-12 28/112 K.LPSSSTWGQQSNTTAC[160.03]QSQATLSLAEIQK.L "sp|Q6Y7W6|GGYF2_HUMAN,tr|A0A7I2V3H7|A0A7I2V3H7_HUMAN,tr|I1E4Y6|I1E4Y6_HUMAN,tr|A0A7I2V516|A0A7I2V516_HUMAN,tr|A0A7I2V3H0|A0A7I2V3H0_HUMAN,tr|A0A7I2V361|A0A7I2V361_HUMAN" 6 3121.4986 2.59 89223 21989 3 3121.510725 1041.5068 GRB10-interacting GYF protein 2 OS=Homo sapiens OX=9606 GN=GIGYF2 PE=1 SV=1 5.99 3397.6 - 2.68E+06 - - - 3.8821 - 5.189 0.721 - 808.3 1 2 0 0.0121 29 0 0 0 3.60E+07 1.39E+07 - - - 10.3632 0.9999 221125_WJC_METTL3_EV_vs_WT_F06.21991.21991.3 3.74E-09 17/68 K.QQLSAEELDAQLDAYNAR[166.11].M "sp|Q86V81|THOC4_HUMAN,tr|E9PB61|E9PB61_HUMAN" 2 2043.9737 1.71 89225 21991 3 2043.980225 682.3318 THO complex subunit 4 OS=Homo sapiens OX=9606 GN=ALYREF PE=1 SV=3 3.92 3397.7 - 1.59E+06 - - - 3.2006 - 3.362 0.562 - 362.8 1 2 0 0.0065 18 0 0 0 1.82E+07 1.06E+07 - - - 7.8233 1 221125_WJC_METTL3_EV_vs_WT_F06.21992.21992.3 4.87E-09 20/68 K.QQLSAEELDAQLDAYNAR.M "sp|Q86V81|THOC4_HUMAN,tr|E9PB61|E9PB61_HUMAN" 2 2033.9654 1.75 89226 21992 3 2033.967638 678.9957 THO complex subunit 4 OS=Homo sapiens OX=9606 GN=ALYREF PE=1 SV=3 3.92 3397.8 - 1.57E+06 - - - 1.0939 - 4.061 0.594 - 495.5 1 2 0 0.0022 18 0 0 0 1.85E+07 1.06E+07 - - - 8.6516 1 221125_WJC_METTL3_EV_vs_WT_F06.21994.21994.3 4.74E-11 25/108 R.K[136.11]VVGSMPTAGSAGSVPENLNLFPEPGSK[136.11].S "sp|Q8WU79|SMAP2_HUMAN,tr|A0A087WV97|A0A087WV97_HUMAN" 2 2785.4291 2.51 89228 21994 3 2785.433187 929.4837 Stromal membrane-associated protein 2 OS=Homo sapiens OX=9606 GN=SMAP2 PE=1 SV=1 6.14 3398 - 1.03E+06 - - - 1.4561 - 4.105 0.611 - 457.8 1 2 0 0.0041 28 0 0 0 7.55E+07 3.01E+07 - - - 8.5999 1 221125_WJC_METTL3_EV_vs_WT_F06.21996.21996.2 3.15E-12 14/34 K.QQLSAEELDAQLDAYNAR[166.11].M "sp|Q86V81|THOC4_HUMAN,tr|E9PB61|E9PB61_HUMAN" 2 2043.9737 0.8 89230 21996 2 2043.978816 1022.9941 THO complex subunit 4 OS=Homo sapiens OX=9606 GN=ALYREF PE=1 SV=3 3.92 3398.2 - 548560 - - - 2.5113 - 3.419 0.626 - 548.3 1 2 0 0.0051 18 0 0 0 3.86E+06 4.83E+06 - - - 6.6854 0.9998 221125_WJC_METTL3_EV_vs_WT_F06.22002.22002.4 2.75E-07 26/114 K.SDKDLETQVIQLNEQVHSLK.L sp|Q15555|MARE2_HUMAN 1 2323.202 1.03 89234 22002 4 2323.207309 581.8078 Microtubule-associated protein RP\EB family member 2 OS=Homo sapiens OX=9606 GN=MAPRE2 PE=1 SV=1 4.75 3399 - 1.95E+06 - - - 2.305 - 4.265 0.498 - 709.9 1 2 1 0.0054 20 0 0 0 1.59E+07 1.55E+07 - - - 4.044 1 221125_WJC_METTL3_EV_vs_WT_F06.22005.22005.3 3.37E-16 23/112 K.LPSSSTWGQQSNTTAC[160.03]QSQATLSLAEIQK[136.11].L "sp|Q6Y7W6|GGYF2_HUMAN,tr|A0A7I2V3H7|A0A7I2V3H7_HUMAN,tr|I1E4Y6|I1E4Y6_HUMAN,tr|A0A7I2V516|A0A7I2V516_HUMAN,tr|A0A7I2V3H0|A0A7I2V3H0_HUMAN,tr|A0A7I2V361|A0A7I2V361_HUMAN" 6 3129.5128 2.59 89237 22005 3 3129.52272 1044.1782 GRB10-interacting GYF protein 2 OS=Homo sapiens OX=9606 GN=GIGYF2 PE=1 SV=1 5.99 3399.4 - 1.26E+06 - - - 3.1676 - 4.454 0.744 - 567.1 1 2 0 0.0099 29 0 0 0 3.60E+07 1.39E+07 - - - 10.2688 0.9995 221125_WJC_METTL3_EV_vs_WT_F06.22010.22010.3 2.08E-07 15/68 K.TVTNAVVTVPAYFNDSQR.Q "sp|P11142|HSP7C_HUMAN,tr|E9PQQ4|E9PQQ4_HUMAN,tr|E9PN89|E9PN89_HUMAN,tr|E9PLF4|E9PLF4_HUMAN,tr|E9PI65|E9PI65_HUMAN,tr|E9PK54|E9PK54_HUMAN,tr|E9PQK7|E9PQK7_HUMAN" 7 1980.9905 0.12 89240 22010 3 1981.000604 661.3374 Heat shock cognate 71 kDa protein OS=Homo sapiens OX=9606 GN=HSPA8 PE=1 SV=1 5.5 3400 - 685640 - - - 5.098 - 2.547 0.517 - 260.7 1 2 0 0.0101 18 0 0 0 1.30E+07 1.10E+08 - - - 6.6293 0.9939 221125_WJC_METTL3_EV_vs_WT_F06.22013.22013.4 0.000126 19/114 R.FKTPEDAQAVINAYTEINKK.H "sp|Q4G0J3|LARP7_HUMAN,tr|H0YA82|H0YA82_HUMAN" 2 2279.1798 1.19 89243 22013 4 2279.194942 570.8022 La-related protein 7 OS=Homo sapiens OX=9606 GN=LARP7 PE=1 SV=1 6.18 3400.4 - 701915 - - - 6.6603 - 3.65 0.48 - 360.3 1 2 1 0.0152 20 0 0 0 7.49E+06 6.28E+06 - - - 3.8326 0.9942 221125_WJC_METTL3_EV_vs_WT_F06.22014.22014.3 2.03E-05 19/72 K.ISSIQSIVPALEIANAHR[166.11]K[136.11].P "sp|P10809|CH60_HUMAN,tr|A0A7I2V2X6|A0A7I2V2X6_HUMAN,tr|A0A7I2YQK6|A0A7I2YQK6_HUMAN,tr|A0A7I2V599|A0A7I2V599_HUMAN,tr|A0A7I2YQ71|A0A7I2YQ71_HUMAN,tr|A0A7I2V5M1|A0A7I2V5M1_HUMAN,tr|A0A7I2V5K3|A0A7I2V5K3_HUMAN,tr|A0A7I2V369|A0A7I2V369_HUMAN" 8 2064.181 1.62 89244 22014 3 2064.184811 689.0676 "60 kDa heat shock protein, mitochondrial OS=Homo sapiens OX=9606 GN=HSPD1 PE=1 SV=2" 8.75 3400.5 - 674646 - - - 1.8254 - 2.968 0.468 - 325.6 1 1 0 0.0038 19 0 0 0 2.35E+07 1.46E+07 - - - 6.4294 0.9996 221125_WJC_METTL3_EV_vs_WT_F06.22015.22015.4 3.14E-06 14/108 K.IKENKPLPPVPIPNLVGIR.G sp|O60476|MA1A2_HUMAN 1 2093.2725 1.21 89245 22015 4 2093.27907 524.3254 "Mannosyl-oligosaccharide 1,2-alpha-mannosidase IB OS=Homo sapiens OX=9606 GN=MAN1A2 PE=1 SV=1" 9.99 3400.6 - 592575 - - - 3.1477 - 3.04 0.524 - 173.2 1 2 1 0.0066 19 0 0 0 3.78E+06 3.11E+06 - - - 4.1612 1 221125_WJC_METTL3_EV_vs_WT_F06.22017.22017.3 1.99E-11 18/120 R.GTLQLAGAVISPSDEDSHTFTVNAASGEQYK[136.11].L sp|Q9BXB4|OSB11_HUMAN 1 3200.5353 2.02 89247 22017 3 3200.540464 1067.8524 Oxysterol-binding protein-related protein 11 OS=Homo sapiens OX=9606 GN=OSBPL11 PE=1 SV=2 4.31 3400.9 - 341647 - - - 1.6082 - 3.557 0.559 - 269.1 1 2 0 0.0051 31 0 0 0 5.64E+06 2.79E+06 - - - 7.6902 0.9996 221125_WJC_METTL3_EV_vs_WT_F06.22020.22020.2 0.00428 16-Oct R.YLDVSILGK[136.11].F sp|Q86U44|MTA70_HUMAN 1 1014.5841 0.02 89248 22020 2 1014.58651 508.2993 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 5.83 3401.3 - 945632 - - - 2.3773 - 1.97 0.489 - 241.7 1 2 0 0.0024 9 0 0 0 3.90E+06 2.03E+08 - - - 4.6136 0.9999 221125_WJC_METTL3_EV_vs_WT_F06.22022.22022.4 1.12E-09 22/144 R.GSHPWQVALLSGNQLHC[160.03]GGVLVNER.W sp|P49862|KLK7_HUMAN 1 2727.3664 7.6 89250 22022 4 2727.376361 682.8489 Kallikrein-7 OS=Homo sapiens OX=9606 GN=KLK7 PE=1 SV=1 6.91 3401.6 - 1.24E+06 - - - 3.6698 - 4.408 0.568 - 343.2 1 2 0 0.01 25 0 0 0 3.45E+07 4.54E+06 - - - 4.639 1 221125_WJC_METTL3_EV_vs_WT_F06.22023.22023.3 5.98E-09 18/112 R.GQAAQPEPSTGFTATPPAPDSPQEPLVLR.L "sp|Q9BVT8|TMUB1_HUMAN,tr|C9JE12|C9JE12_HUMAN,tr|A0A590UJA9|A0A590UJA9_HUMAN,tr|C9JCW7|C9JCW7_HUMAN" 4 2958.4723 1.32 89251 22023 3 2958.474788 987.1647 Transmembrane and ubiquitin-like domain-containing protein 1 OS=Homo sapiens OX=9606 GN=TMUB1 PE=1 SV=1 4.14 3401.7 - 659980 - - - 0.8356 - 3.333 0.639 - 152.4 1 2 0 0.0025 29 0 0 0 9.87E+06 7.49E+06 - - - 8.4332 0.9962 221125_WJC_METTL3_EV_vs_WT_F06.22029.22029.4 0.00062 17/150 K.QLPDK[136.11]WQHDLFDSGFGGGAGVETGGK[136.11].L "sp|Q86V81|THOC4_HUMAN,tr|E9PB61|E9PB61_HUMAN" 2 2718.3009 0.74 89255 22029 4 2718.304678 680.5825 THO complex subunit 4 OS=Homo sapiens OX=9606 GN=ALYREF PE=1 SV=3 4.66 3402.5 - 1.85E+06 - - - 1.392 - 2.786 0.294 - 115.2 1 2 1 0.0038 26 0 0 0 1.59E+08 2.15E+08 - - - 2.1071 0.9938 221125_WJC_METTL3_EV_vs_WT_F06.22033.22033.4 0.00237 18/114 R.FK[136.11]TPEDAQAVINAYTEINK[136.11]K[136.11].H "sp|Q4G0J3|LARP7_HUMAN,tr|H0YA82|H0YA82_HUMAN" 2 2303.2224 1.18 89259 22033 4 2303.232102 576.8129 La-related protein 7 OS=Homo sapiens OX=9606 GN=LARP7 PE=1 SV=1 6.18 3402.8 - 571289 - - - 4.2289 - 2.459 0.376 - 65.7 1 2 1 0.0097 20 0 0 0 7.42E+06 6.28E+06 - - - 2.7968 0.9997 221125_WJC_METTL3_EV_vs_WT_F06.22038.22038.4 6.81E-07 26/150 K.QLPDKWQHDLFDSGFGGGAGVETGGK.L "sp|Q86V81|THOC4_HUMAN,tr|E9PB61|E9PB61_HUMAN" 2 2702.2725 0.74 89262 22038 4 2702.279812 676.5754 THO complex subunit 4 OS=Homo sapiens OX=9606 GN=ALYREF PE=1 SV=3 4.66 3403.5 - 2.82E+06 - - - 2.7081 - 3.297 0.521 - 301.3 1 2 1 0.0073 26 0 0 0 1.59E+08 2.16E+08 - - - 4.1351 1 221125_WJC_METTL3_EV_vs_WT_F06.22041.22041.3 1.14E-09 18/68 K.YVHYEIDAC[160.03]MDSEAPGSK[136.11].D "sp|Q86U44|MTA70_HUMAN,tr|H0YFV6|H0YFV6_HUMAN" 2 2078.8805 0.01 89265 22041 3 2078.887041 693.9674 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 4.31 3403.8 - 915450 - - - 3.1503 - 3.479 0.62 - 360.5 1 2 0 0.0065 18 0 0 0 1.79E+05 1.89E+07 - - - 8.5551 0.9998 221125_WJC_METTL3_EV_vs_WT_F06.22042.22042.3 4.09E-09 20/100 K.QLPDK[136.11]WQHDLFDSGFGGGAGVETGGK[136.11].L "sp|Q86V81|THOC4_HUMAN,tr|E9PB61|E9PB61_HUMAN" 2 2718.3009 0.71 89266 22042 3 2718.309096 907.1076 THO complex subunit 4 OS=Homo sapiens OX=9606 GN=ALYREF PE=1 SV=3 4.66 3403.9 - 739683 - - - 3.0173 - 3.735 0.564 - 281.2 1 2 1 0.0082 26 0 0 0 2.83E+07 3.96E+07 - - - 7.8574 1 221125_WJC_METTL3_EV_vs_WT_F06.22043.22043.3 2.72E-11 17/84 K.NADMSEEMQQDSVEC[160.03]ATQALEK[136.11].Y "sp|P63167|DYL1_HUMAN,tr|F8VXI7|F8VXI7_HUMAN,tr|F8VXL2|F8VXL2_HUMAN,tr|F8VRV5|F8VRV5_HUMAN" 4 2521.0498 1.49 89267 22043 3 2521.055131 841.3572 "Dynein light chain 1, cytoplasmic OS=Homo sapiens OX=9606 GN=DYNLL1 PE=1 SV=1" 3.77 3404 - 708734 - - - 2.1071 - 3.663 0.75 - 432.5 1 2 0 0.0053 22 0 0 0 3.68E+07 2.47E+07 - - - 9.9783 0.9997 221125_WJC_METTL3_EV_vs_WT_F06.22047.22047.3 1.63E-08 16/72 R.GLLQDDAHPTLVTYADHSK[136.11].L "sp|Q86U44|MTA70_HUMAN,tr|F5H6D8|F5H6D8_HUMAN,tr|H0YFV6|H0YFV6_HUMAN,tr|B4DTN4|B4DTN4_HUMAN" 4 2088.0367 0.21 89271 22047 3 2088.044761 697.0195 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 5.13 3404.6 - 490214 - - - 3.8448 - 3.09 0.42 - 278.5 1 2 0 0.008 19 0 0 0 3.00E+06 1.42E+07 - - - 5.9921 0.9999 221125_WJC_METTL3_EV_vs_WT_F06.22048.22048.3 1.12E-07 17/68 R.REFQLDLDEIENDNGTVR.C "sp|Q14008|CKAP5_HUMAN,tr|H0YEK7|H0YEK7_HUMAN,tr|H0YCF6|H0YCF6_HUMAN" 3 2162.024 0.64 89272 22048 3 2162.033481 721.6819 Cytoskeleton-associated protein 5 OS=Homo sapiens OX=9606 GN=CKAP5 PE=1 SV=3 4.02 3404.7 - 437339 - - - 4.3899 - 3.156 0.601 - 392.7 1 2 0 0.0095 18 0 0 0 7.17E+06 1.12E+07 - - - 8.0998 1 221125_WJC_METTL3_EV_vs_WT_F06.22051.22051.3 1.74E-09 19/100 K.QLPDKWQHDLFDSGFGGGAGVETGGK.L "sp|Q86V81|THOC4_HUMAN,tr|E9PB61|E9PB61_HUMAN" 2 2702.2725 0.71 89275 22051 3 2702.279067 901.7648 THO complex subunit 4 OS=Homo sapiens OX=9606 GN=ALYREF PE=1 SV=3 4.66 3405.1 - 408188 - - - 2.4324 - 3.783 0.638 - 298.6 1 2 1 0.0066 26 0 0 0 2.83E+07 3.96E+07 - - - 8.7123 1 221125_WJC_METTL3_EV_vs_WT_F06.22052.22052.3 5.48E-09 16/112 R.GQAAQPEPSTGFTATPPAPDSPQEPLVLR[166.11].L "sp|Q9BVT8|TMUB1_HUMAN,tr|C9JE12|C9JE12_HUMAN,tr|A0A590UJA9|A0A590UJA9_HUMAN,tr|C9JCW7|C9JCW7_HUMAN" 4 2968.4806 1.32 89276 22052 3 2968.488484 990.5008 Transmembrane and ubiquitin-like domain-containing protein 1 OS=Homo sapiens OX=9606 GN=TMUB1 PE=1 SV=1 4.14 3405.2 - 368952 - - - 2.6606 - 3.184 0.614 - 122.6 1 2 0 0.0079 29 0 0 0 9.87E+06 7.49E+06 - - - 8.0478 1 221125_WJC_METTL3_EV_vs_WT_F06.22053.22053.3 8.29E-11 26/96 R.GSHPWQVALLSGNQLHC[160.03]GGVLVNER.W sp|P49862|KLK7_HUMAN 1 2727.3664 28.6 89277 22053 3 2727.373835 910.1294 Kallikrein-7 OS=Homo sapiens OX=9606 GN=KLK7 PE=1 SV=1 6.91 3405.4 - 366635 - - - 2.7437 - 4.708 0.728 - 643.5 1 2 0 0.0075 25 0 0 0 3.55E+06 1.24E+05 - - - 10.2187 1 221125_WJC_METTL3_EV_vs_WT_F06.22056.22056.3 1.29E-08 18/76 K.EK[136.11]PSYDTETDPSEGLMNVLK[136.11].K sp|Q9HB71|CYBP_HUMAN 1 2268.0802 0.45 89278 22056 3 2268.076684 757.034 Calcyclin-binding protein OS=Homo sapiens OX=9606 GN=CACYBP PE=1 SV=2 4.18 3405.8 - 2.65E+06 - - - -1.5696 - 2.825 0.581 - 380 1 2 0 -0.0036 20 0 0 0 2.91E+07 6.53E+07 - - - 7.536 0.9998 221125_WJC_METTL3_EV_vs_WT_F06.22057.22057.3 0.000272 15/76 K.EKPSYDTETDPSEGLMNVLK.K sp|Q9HB71|CYBP_HUMAN 1 2252.0518 0.44 89279 22057 3 2252.056894 751.6912 Calcyclin-binding protein OS=Homo sapiens OX=9606 GN=CACYBP PE=1 SV=2 4.18 3405.9 - 1.57E+06 - - - 2.2424 - 2.524 0.416 - 280.5 1 2 0 0.005 20 0 0 0 2.90E+07 6.53E+07 - - - 5.4227 1 221125_WJC_METTL3_EV_vs_WT_F06.22058.22058.3 8.62E-13 22/84 K.NADMSEEMQQDSVEC[160.03]ATQALEK.Y "sp|P63167|DYL1_HUMAN,tr|F8VXI7|F8VXI7_HUMAN,tr|F8VXL2|F8VXL2_HUMAN,tr|F8VRV5|F8VRV5_HUMAN" 4 2513.0356 1.49 89280 22058 3 2513.038842 838.6858 "Dynein light chain 1, cytoplasmic OS=Homo sapiens OX=9606 GN=DYNLL1 PE=1 SV=1" 3.77 3405.9 - 2.06E+06 - - - 1.2825 - 3.96 0.767 - 781.1 1 2 0 0.0032 22 0 0 0 3.68E+07 2.47E+07 - - - 10.3532 1 221125_WJC_METTL3_EV_vs_WT_F06.22066.22066.3 6.90E-08 18/104 R.TLYDAELSQMQSHISDTSVVLSMDNNR.S sp|P12035|K2C3_HUMAN 1 3053.407 999 89286 22066 3 3053.409103 1018.8096 "Keratin, type II cytoskeletal 3 OS=Homo sapiens OX=9606 GN=KRT3 PE=1 SV=3" 4.22 3406.9 - 2.85E+06 - - - 0.6838 - 3.142 0.547 - 280.5 1 2 0 0.0021 27 0 0 0 5.77E+07 0.00E+00 - - - 7.2718 0.9998 221125_WJC_METTL3_EV_vs_WT_F06.22067.22067.4 7.40E-05 16/174 K.LLQIAGISPHGNALGASMQQQVNQQIPQEK.R sp|O76031|CLPX_HUMAN 1 3197.6615 1.41 89287 22067 4 3197.663924 800.4227 "ATP-dependent Clp protease ATP-binding subunit clpX-like, mitochondrial OS=Homo sapiens OX=9606 GN=CLPX PE=1 SV=2" 6.75 3407 - 1.57E+06 - - - 0.7487 - 2.593 0.395 - 81.9 1 2 0 0.0024 30 0 0 0 1.30E+07 9.22E+06 - - - 2.955 0.9988 221125_WJC_METTL3_EV_vs_WT_F06.22068.22068.2 0.0187 16-Aug R.YLDVSILGK.F sp|Q86U44|MTA70_HUMAN 1 1006.5699 0.02 89288 22068 2 1006.572819 504.2922 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 5.83 3407.2 - 367264 - - - 2.9019 - 1.72 0.41 - 135.1 1 2 0 0.0029 9 0 0 0 3.90E+06 2.02E+08 - - - 3.6373 1 221125_WJC_METTL3_EV_vs_WT_F06.22075.22075.4 2.53E-11 21/120 K.KGDTFSC[160.03]MVGHEALPLAFTQK.T "sp|P01876|IGHA1_HUMAN,tr|A0A286YEY1|A0A286YEY1_HUMAN,tr|A0A0G2JMB2|A0A0G2JMB2_HUMAN" 3 2336.1293 391.01 89293 22075 4 2336.134676 585.0396 Immunoglobulin heavy constant alpha 1 OS=Homo sapiens OX=9606 GN=IGHA1 PE=1 SV=2 6.74 3408 - 885430 - - - 2.291 - 3.454 0.603 - 274.7 1 2 0 0.0054 21 0 0 0 2.70E+07 6.90E+04 - - - 4.8829 0.9996 221125_WJC_METTL3_EV_vs_WT_F06.22079.22079.4 4.84E-07 26/138 R.IGNSGVEEIKGHPFFEGVDWEHIR.E sp|Q9Y2H1|ST38L_HUMAN 1 2751.3405 5.99 89295 22079 4 2751.350874 688.8424 Serine\threonine-protein kinase 38-like OS=Homo sapiens OX=9606 GN=STK38L PE=1 SV=3 4.92 3408.5 - 1.05E+06 - - - 3.7654 - 4.477 0.565 - 543 1 2 1 0.0104 24 0 0 0 1.59E+07 2.65E+06 - - - 4.622 1 221125_WJC_METTL3_EV_vs_WT_F06.22081.22081.3 2.44E-12 19/80 K.KGDTFSC[160.03]MVGHEALPLAFTQK.T "sp|P01876|IGHA1_HUMAN,tr|A0A286YEY1|A0A286YEY1_HUMAN,tr|A0A0G2JMB2|A0A0G2JMB2_HUMAN" 3 2336.1293 147.06 89297 22081 3 2336.135909 779.7171 Immunoglobulin heavy constant alpha 1 OS=Homo sapiens OX=9606 GN=IGHA1 PE=1 SV=2 6.74 3408.8 - 731770 - - - 2.8188 - 3.866 0.665 - 407.8 1 2 0 0.0066 21 0 0 0 1.45E+07 9.87E+04 - - - 9.1942 1 221125_WJC_METTL3_EV_vs_WT_F06.22088.22088.4 9.59E-08 16/126 K.GYLTDLNSMIPTHGGDINDIKK.A sp|O94906|PRP6_HUMAN 1 2401.1948 2.23 89302 22088 4 2401.198133 601.306 Pre-mRNA-processing factor 6 OS=Homo sapiens OX=9606 GN=PRPF6 PE=1 SV=1 5.3 3409.7 - 611979 - - - 1.4043 - 2.856 0.505 - 65.9 1 2 0 0.0034 22 0 0 0 8.15E+07 3.66E+07 - - - 3.964 1 221125_WJC_METTL3_EV_vs_WT_F06.22089.22089.2 5.20E-08 13/26 R.GLLQDDAHPTLVTY.A "sp|Q86U44|MTA70_HUMAN,tr|F5H6D8|F5H6D8_HUMAN,tr|H0YFV6|H0YFV6_HUMAN,tr|B4DTN4|B4DTN4_HUMAN" 4 1541.7726 - 89303 22089 2 1541.775944 771.8936 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 4.2 3409.9 - 1.44E+06 - - - 2.1864 - 2.64 0.579 - 412.2 1 1 0 0.0034 14 0 0 0 - - - - - 5.7526 1 221125_WJC_METTL3_EV_vs_WT_F06.22096.22096.4 6.33E-06 28/174 R.TVPAVAAHPLIAPAYAQLQPHQLLPQPSSK.H "sp|Q8IXK0|PHC2_HUMAN,tr|A0A0A0MSI2|A0A0A0MSI2_HUMAN" 2 3142.7291 2.58 89308 22096 4 3142.734655 786.6896 Polyhomeotic-like protein 2 OS=Homo sapiens OX=9606 GN=PHC2 PE=1 SV=1 8.31 3410.8 - 1.35E+06 - - - 1.7548 - 3.513 0.512 - 312.9 1 2 0 0.0055 30 0 0 0 3.12E+07 1.21E+07 - - - 4.0654 1 221125_WJC_METTL3_EV_vs_WT_F06.22101.22101.3 5.63E-06 16/56 R.GFAFVTFDDHDSVDK.L "sp|Q32P51|RA1L2_HUMAN,sp|P09651|ROA1_HUMAN,tr|A0A7I2YQX9|A0A7I2YQX9_HUMAN,tr|F8VZ49|F8VZ49_HUMAN,tr|A0A7I2V3R8|A0A7I2V3R8_HUMAN,tr|F8VTQ5|F8VTQ5_HUMAN,tr|F8W6I7|F8W6I7_HUMAN,tr|H0YH80|H0YH80_HUMAN,tr|A0A7I2V2L6|A0A7I2V2L6_HUMAN,tr|A0A7I2V3W0|A0A7I2V3W0_HUMAN,tr|A0A7I2V5U9|A0A7I2V5U9_HUMAN,tr|A0A2R8Y4L2|A0A2R8Y4L2_HUMAN" 12 1698.7526 1.35 89313 22101 3 1698.752868 567.2581 Heterogeneous nuclear ribonucleoprotein A1-like 2 OS=Homo sapiens OX=9606 GN=HNRNPA1L2 PE=2 SV=2 4.13 3411.4 - 633006 - - - 0.1778 - 2.887 0.583 - 199.1 1 2 0 0.0003 15 0 0 0 1.32E+07 9.77E+06 - - - 7.8063 1 221125_WJC_METTL3_EV_vs_WT_F06.22102.22102.3 1.74E-09 15/56 R.GFAFVTFDDHDSVDK[136.11].L "sp|Q32P51|RA1L2_HUMAN,sp|P09651|ROA1_HUMAN,tr|A0A7I2YQX9|A0A7I2YQX9_HUMAN,tr|F8VZ49|F8VZ49_HUMAN,tr|A0A7I2V3R8|A0A7I2V3R8_HUMAN,tr|F8VTQ5|F8VTQ5_HUMAN,tr|F8W6I7|F8W6I7_HUMAN,tr|H0YH80|H0YH80_HUMAN,tr|A0A7I2V2L6|A0A7I2V2L6_HUMAN,tr|A0A7I2V3W0|A0A7I2V3W0_HUMAN,tr|A0A7I2V5U9|A0A7I2V5U9_HUMAN,tr|A0A2R8Y4L2|A0A2R8Y4L2_HUMAN" 12 1706.7668 3.4 89314 22102 3 1706.765385 569.9295 Heterogeneous nuclear ribonucleoprotein A1-like 2 OS=Homo sapiens OX=9606 GN=HNRNPA1L2 PE=2 SV=2 4.13 3411.6 - 583875 - - - -0.8091 - 3.234 0.669 - 166.9 1 2 0 -0.0014 15 0 0 0 3.46E+07 1.02E+07 - - - 9.061 0.9999 221125_WJC_METTL3_EV_vs_WT_F06.22108.22108.4 3.28E-05 8/126 R.DC[160.03]WSTC[160.03]TLSHDIHTPVNMQVLK[136.11].S sp|Q96H79|ZCCHL_HUMAN 1 2649.2229 1 89318 22108 4 2649.22398 663.313 Zinc finger CCCH-type antiviral protein 1-like OS=Homo sapiens OX=9606 GN=ZC3HAV1L PE=1 SV=2 5.98 3412.4 - 581039 - - - 0.4028 - 1.687 0.48 - 23.5 1 2 0 0.0011 22 0 0 0 1.58E+07 1.59E+07 - - - 3.5747 0.9986 221125_WJC_METTL3_EV_vs_WT_F06.22110.22110.3 7.33E-08 14/96 K.SSEDDAASESFLPSEGASSDPVTLR.R "sp|Q9UKV5|AMFR_HUMAN,tr|R4GNG2|R4GNG2_HUMAN" 2 2553.1355 1.25 89320 22110 3 2554.136805 852.0524 E3 ubiquitin-protein ligase AMFR OS=Homo sapiens OX=9606 GN=AMFR PE=1 SV=2 3.71 3412.6 - 689834 - - - 392.2056 - 2.631 0.479 - 119.7 1 2 0 1.0014 25 0 0 0 1.26E+07 1.00E+07 - - - 5.8286 1 221125_WJC_METTL3_EV_vs_WT_F06.22112.22112.3 1.67E-13 18/100 K.AITSGGITYQDQPWHADC[160.03]FVC[160.03]VTC[160.03]SK.K "sp|Q13642|FHL1_HUMAN,tr|A0A494C0D6|A0A494C0D6_HUMAN,tr|Q5JXH7|Q5JXH7_HUMAN,tr|Q5JXI8|Q5JXI8_HUMAN,tr|Q5JXH8|Q5JXH8_HUMAN,tr|Q5JXI3|Q5JXI3_HUMAN" 6 3000.3204 0.65 89322 22112 3 3000.319652 1001.1141 Four and a half LIM domains protein 1 OS=Homo sapiens OX=9606 GN=FHL1 PE=1 SV=4 5.21 3412.9 - 425610 - - - -0.2656 - 3.825 0.74 - 292.8 1 2 0 -0.0008 26 0 0 0 4.39E+06 6.78E+06 - - - 9.8765 1 221125_WJC_METTL3_EV_vs_WT_F06.22113.22113.3 8.78E-08 16/88 K.K[136.11]PSVPETEADGFVLLGDTTDEQR[166.11].M "sp|C9J7I0|UMAD1_HUMAN,tr|A0A1B0GUC2|A0A1B0GUC2_HUMAN,tr|A0A1W2PP33|A0A1W2PP33_HUMAN" 3 2521.2303 5.13 89323 22113 3 2521.232889 841.4174 UBAP1-MVB12-associated (UMA)-domain containing protein 1 OS=Homo sapiens OX=9606 GN=UMAD1 PE=1 SV=2 4.02 3413 - 291825 - - - 1.0277 - 3.209 0.462 - 230.8 1 2 0 0.0026 23 0 0 0 2.99E+07 5.83E+06 - - - 6.4254 0.9995 221125_WJC_METTL3_EV_vs_WT_F06.22115.22115.3 1.54E-08 17/76 R.HYYTGTQGLIFVVDC[160.03]ADR[166.11]DR[166.11].L sp|P62330|ARF6_HUMAN 1 2405.1337 1.23 89325 22115 3 2405.142488 802.7185 ADP-ribosylation factor 6 OS=Homo sapiens OX=9606 GN=ARF6 PE=1 SV=2 5.3 3413.3 - 266727 - - - 3.646 - 2.842 0.55 - 252.6 1 2 1 0.0088 20 0 0 0 2.41E+07 1.96E+07 - - - 7.2035 0.9972 221125_WJC_METTL3_EV_vs_WT_F06.22120.22120.3 2.88E-08 19/84 F.SATFDYQQAFGNSTGGFDGQAR.Q sp|Q96PK6|RBM14_HUMAN 1 2324.0094 1.49 89328 22120 3 2324.015157 775.6771 RNA-binding protein 14 OS=Homo sapiens OX=9606 GN=RBM14 PE=1 SV=2 4.21 3413.9 - 633752 - - - 2.4759 - 3.447 0.611 - 340 1 1 0 0.0058 22 0 0 0 8.04E+06 5.40E+06 - - - 8.2844 1 221125_WJC_METTL3_EV_vs_WT_F06.22124.22124.3 2.55E-14 17/88 R.WVYPLTPEANFTDSTTQSC[160.03]THSR[166.11].H "sp|Q13144|EI2BE_HUMAN,tr|A0A3B3ISX3|A0A3B3ISX3_HUMAN,tr|A0A3B3ITG6|A0A3B3ITG6_HUMAN,tr|A0A3B3IUF2|A0A3B3IUF2_HUMAN,tr|A0A3B3ISM8|A0A3B3ISM8_HUMAN,tr|A0A3B3ISV1|A0A3B3ISV1_HUMAN,tr|A0A3B3IUB1|A0A3B3IUB1_HUMAN,tr|A0A3B3ITQ2|A0A3B3ITQ2_HUMAN" 8 2707.2212 0.47 89332 22124 3 2707.220082 903.4143 Translation initiation factor eIF-2B subunit epsilon OS=Homo sapiens OX=9606 GN=EIF2B5 PE=1 SV=3 5.32 3414.5 - 312864 - - - -0.413 - 3.817 0.746 - 216.9 1 2 0 -0.0011 23 0 0 0 2.27E+06 4.86E+06 - - - 9.9992 0.9997 221125_WJC_METTL3_EV_vs_WT_F06.22127.22127.3 3.22E-06 16/76 R.HYYTGTQGLIFVVDC[160.03]ADRDR.L sp|P62330|ARF6_HUMAN 1 2385.1172 1.11 89333 22127 3 2385.117257 796.0463 ADP-ribosylation factor 6 OS=Homo sapiens OX=9606 GN=ARF6 PE=1 SV=2 5.3 3414.9 - 704007 - - - 0.0327 - 2.432 0.453 - 228.7 1 2 1 0.0001 20 0 0 0 2.70E+07 2.43E+07 - - - 5.7465 1 221125_WJC_METTL3_EV_vs_WT_F06.22128.22128.3 9.12E-08 17/72 K.KISSIQSIVPALEIANAHR.K "sp|P10809|CH60_HUMAN,tr|A0A7I2V2X6|A0A7I2V2X6_HUMAN,tr|A0A7I2YQK6|A0A7I2YQK6_HUMAN,tr|A0A7I2V599|A0A7I2V599_HUMAN,tr|A0A7I2YQ71|A0A7I2YQ71_HUMAN,tr|A0A7I2V5M1|A0A7I2V5M1_HUMAN,tr|A0A7I2V5K3|A0A7I2V5K3_HUMAN,tr|A0A7I2V369|A0A7I2V369_HUMAN" 8 2046.1586 1.45 89334 22128 3 2046.161545 683.0601 "60 kDa heat shock protein, mitochondrial OS=Homo sapiens OX=9606 GN=HSPD1 PE=1 SV=2" 8.75 3415 - 418809 - - - 1.4525 - 3.598 0.587 - 360.1 1 2 0 0.003 19 0 0 0 3.48E+08 2.39E+08 - - - 8.2293 0.9994 221125_WJC_METTL3_EV_vs_WT_F06.22130.22130.4 2.92E-07 19/114 R.HYYTGTQGLIFVVDC[160.03]ADRDR.L sp|P62330|ARF6_HUMAN 1 2385.1172 1.02 89336 22130 4 2385.127305 597.2866 ADP-ribosylation factor 6 OS=Homo sapiens OX=9606 GN=ARF6 PE=1 SV=2 5.3 3415.3 - 459640 - - - 4.2455 - 2.833 0.563 - 276.6 1 2 1 0.0101 20 0 0 0 1.70E+07 1.67E+07 - - - 4.4717 1 221125_WJC_METTL3_EV_vs_WT_F06.22131.22131.3 1.09E-12 17/100 K.AITSGGITYQDQPWHADC[160.03]FVC[160.03]VTC[160.03]SK[136.11].K "sp|Q13642|FHL1_HUMAN,tr|A0A494C0D6|A0A494C0D6_HUMAN,tr|Q5JXH7|Q5JXH7_HUMAN,tr|Q5JXI8|Q5JXI8_HUMAN,tr|Q5JXH8|Q5JXH8_HUMAN,tr|Q5JXI3|Q5JXI3_HUMAN" 6 3008.3346 0.65 89337 22131 3 3008.343757 1003.7855 Four and a half LIM domains protein 1 OS=Homo sapiens OX=9606 GN=FHL1 PE=1 SV=4 5.21 3415.4 - 294808 - - - 3.0276 - 3.566 0.719 - 269.4 1 2 0 0.0091 26 0 0 0 4.39E+06 6.78E+06 - - - 9.4787 1 221125_WJC_METTL3_EV_vs_WT_F06.22137.22137.4 1.14E-09 18/156 R.HSPPDDLGSSFYPELGPYSSRDPEVLR.E "sp|Q5VSG8|MANEL_HUMAN,tr|H0YCZ3|H0YCZ3_HUMAN" 2 3016.4203 143.68 89341 22137 4 3016.427412 755.1123 "Glycoprotein endo-alpha-1,2-mannosidase-like protein OS=Homo sapiens OX=9606 GN=MANEAL PE=2 SV=1" 4.43 3416.2 - 374483 - - - 2.3644 - 3.282 0.653 - 127.3 1 2 1 0.0071 27 0 0 0 2.52E+08 1.75E+06 - - - 5.2796 1 221125_WJC_METTL3_EV_vs_WT_F06.22143.22143.4 5.15E-09 23/186 R.LENVLFGPHDC[160.03]SHAPPDGYPIIPTSGSVPVQK.Q sp|Q01780|EXOSX_HUMAN 1 3427.6871 1.46 89345 22143 4 3427.693732 857.929 Exosome component 10 OS=Homo sapiens OX=9606 GN=EXOSC10 PE=1 SV=2 5.21 3417 - 1.20E+06 - - - 1.9415 - 3.907 0.644 - 240.7 1 2 0 0.0067 32 0 0 0 5.06E+07 3.47E+07 - - - 5.241 0.9972 221125_WJC_METTL3_EV_vs_WT_F06.22144.22144.3 0.000192 20/96 R.C[160.03]PKPASQIGC[160.03]SAPGYLPTSLAWHPQ.Q "sp|Q9BQA1|MEP50_HUMAN,tr|H0Y711|H0Y711_HUMAN" 2 2722.2996 11.68 89346 22144 3 2722.305941 908.4405 Methylosome protein 50 OS=Homo sapiens OX=9606 GN=WDR77 PE=1 SV=1 8.05 3417.2 - 494572 - - - 2.3377 - 4.002 0.573 - 293.1 1 1 0 0.0064 25 0 0 0 1.41E+07 1.21E+06 - - - 8.1171 1 221125_WJC_METTL3_EV_vs_WT_F06.22145.22145.3 1.42E-10 17/72 K.EKVNVDIINFGEEEVNTEK.L "sp|P55036|PSMD4_HUMAN,sp|A2A3N6|PIPSL_HUMAN,tr|A6PVX3|A6PVX3_HUMAN,tr|Q5VWC4|Q5VWC4_HUMAN" 4 2205.0801 1.16 89347 22145 3 2205.087751 736.034 26S proteasome non-ATPase regulatory subunit 4 OS=Homo sapiens OX=9606 GN=PSMD4 PE=1 SV=1 4.14 3417.2 - 2.40E+06 - - - 3.4661 - 3.572 0.642 - 429.6 1 2 1 0.0076 19 0 0 0 1.17E+08 1.01E+08 - - - 8.8234 1 221125_WJC_METTL3_EV_vs_WT_F06.22146.22146.4 3.38E-16 21/186 R.LENVLFGPHDC[160.03]SHAPPDGYPIIPTSGSVPVQK[136.11].Q sp|Q01780|EXOSX_HUMAN 1 3435.7013 1.46 89348 22146 4 3435.717667 859.9326 Exosome component 10 OS=Homo sapiens OX=9606 GN=EXOSC10 PE=1 SV=2 5.21 3417.4 - 689540 - - - 4.7705 - 3.852 0.716 - 196 1 2 0 0.0164 32 0 0 0 5.05E+07 3.47E+07 - - - 5.8607 1 221125_WJC_METTL3_EV_vs_WT_F06.22148.22148.3 3.55E-10 16/88 R.WVYPLTPEANFTDSTTQSC[160.03]THSR.H "sp|Q13144|EI2BE_HUMAN,tr|A0A3B3ISX3|A0A3B3ISX3_HUMAN,tr|A0A3B3ITG6|A0A3B3ITG6_HUMAN,tr|A0A3B3IUF2|A0A3B3IUF2_HUMAN,tr|A0A3B3ISM8|A0A3B3ISM8_HUMAN,tr|A0A3B3ISV1|A0A3B3ISV1_HUMAN,tr|A0A3B3IUB1|A0A3B3IUB1_HUMAN,tr|A0A3B3ITQ2|A0A3B3ITQ2_HUMAN" 8 2697.2129 0.47 89350 22148 3 2697.215451 900.0783 Translation initiation factor eIF-2B subunit epsilon OS=Homo sapiens OX=9606 GN=EIF2B5 PE=1 SV=3 5.32 3417.6 - 227868 - - - 0.9347 - 3.808 0.744 - 232.3 1 2 0 0.0025 23 0 0 0 2.27E+06 4.86E+06 - - - 9.9709 0.9842 221125_WJC_METTL3_EV_vs_WT_F06.22150.22150.4 1.44E-05 19/120 R.K[136.11]IELFGR[166.11]PHNVQPNWITLGNQ.L sp|Q86U44|MTA70_HUMAN 1 2478.3251 0.02 89351 22150 4 2478.330907 620.5885 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 8.75 3417.9 - 2.50E+06 - - - 2.3504 - 3.308 0.439 - 190.1 1 1 0 0.0058 21 0 0 0 4.67E+07 2.90E+09 - - - 3.441 1 221125_WJC_METTL3_EV_vs_WT_F06.22152.22152.4 1.04E-06 14/108 R.GLLQDDAHPTLVTYADHSK[136.11].L "sp|Q86U44|MTA70_HUMAN,tr|F5H6D8|F5H6D8_HUMAN,tr|H0YFV6|H0YFV6_HUMAN,tr|B4DTN4|B4DTN4_HUMAN" 4 2088.0367 0.02 89352 22152 4 2088.040942 523.0165 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 5.13 3418.1 - 1.17E+06 - - - 2.0158 - 2.908 0.512 - 169.3 1 2 0 0.0042 19 0 0 0 2.80E+05 1.42E+07 - - - 4.0424 1 221125_WJC_METTL3_EV_vs_WT_F06.22159.22159.4 1.31E-10 25/108 K.K[136.11]ISSIQSIVPALEIANAHR[166.11].K "sp|P10809|CH60_HUMAN,tr|A0A7I2V2X6|A0A7I2V2X6_HUMAN,tr|A0A7I2YQK6|A0A7I2YQK6_HUMAN,tr|A0A7I2V599|A0A7I2V599_HUMAN,tr|A0A7I2YQ71|A0A7I2YQ71_HUMAN,tr|A0A7I2V5M1|A0A7I2V5M1_HUMAN,tr|A0A7I2V5K3|A0A7I2V5K3_HUMAN,tr|A0A7I2V369|A0A7I2V369_HUMAN" 8 2064.181 1.33 89357 22159 4 2064.185007 517.0525 "60 kDa heat shock protein, mitochondrial OS=Homo sapiens OX=9606 GN=HSPD1 PE=1 SV=2" 8.75 3419 - 1.21E+06 - - - 1.9204 - 4.382 0.617 - 668.7 1 2 0 0.004 19 0 0 0 6.47E+08 4.86E+08 - - - 5.0951 1 221125_WJC_METTL3_EV_vs_WT_F06.22160.22160.4 7.84E-10 19/126 K.GYLTDLNSMIPTHGGDINDIK[136.11]K[136.11].A sp|O94906|PRP6_HUMAN 1 2417.2232 2.24 89358 22160 4 2417.229431 605.3131 Pre-mRNA-processing factor 6 OS=Homo sapiens OX=9606 GN=PRPF6 PE=1 SV=1 5.3 3419.1 - 1.30E+06 - - - 2.5939 - 3.367 0.62 - 190.2 1 2 0 0.0063 22 0 0 0 8.08E+07 3.61E+07 - - - 5.018 1 221125_WJC_METTL3_EV_vs_WT_F06.22162.22162.4 1.36E-09 23/138 K.LNC[160.03]QVIGASVDSHFC[160.03]HLAWVNTPK[136.11].K "sp|Q06830|PRDX1_HUMAN,tr|A0A0A0MSI0|A0A0A0MSI0_HUMAN" 2 2760.3356 0.23 89360 22162 4 2760.336821 691.0912 Peroxiredoxin-1 OS=Homo sapiens OX=9606 GN=PRDX1 PE=1 SV=1 6.9 3419.3 - 900580 - - - 0.4514 - 4.088 0.598 - 399.4 1 2 0 0.0012 24 0 0 0 1.24E+07 5.26E+07 - - - 4.8826 1 221125_WJC_METTL3_EV_vs_WT_F06.22164.22164.3 9.16E-18 23/124 R.FSGFGSGAGGKPLEGLSNGNNITSAPPFASAK.A "sp|Q9UKX7|NUP50_HUMAN,tr|B0QY21|B0QY21_HUMAN" 2 3036.4941 1.64 89362 22164 3 3036.502413 1013.172 Nuclear pore complex protein Nup50 OS=Homo sapiens OX=9606 GN=NUP50 PE=1 SV=2 8.59 3419.6 - 592312 - - - 2.7331 - 4.329 0.711 - 215 1 2 0 0.0083 32 0 0 0 1.24E+08 7.56E+07 - - - 9.8359 0.9984 221125_WJC_METTL3_EV_vs_WT_F06.22166.22166.3 5.40E-06 10/104 R.AEAVESAQAGDK[136.11]C[160.03]DFTGTLIVVPDVSK[136.11].L sp|Q14566|MCM6_HUMAN 1 2822.3979 0.92 89364 22166 3 2822.408756 941.8066 DNA replication licensing factor MCM6 OS=Homo sapiens OX=9606 GN=MCM6 PE=1 SV=1 4.11 3419.9 - 356398 - - - 3.8496 - 1.886 0.53 - 62.4 1 2 1 0.0109 27 0 0 0 3.79E+06 4.11E+06 - - - 5.9056 0.9999 221125_WJC_METTL3_EV_vs_WT_F06.22167.22167.4 2.78E-06 14/84 R.RDTFNHLTTWLEDAR.Q "sp|P61019|RAB2A_HUMAN,tr|H7C125|H7C125_HUMAN,tr|E9PKL7|E9PKL7_HUMAN" 3 1873.9071 1.47 89365 22167 4 1873.911795 469.4841 Ras-related protein Rab-2A OS=Homo sapiens OX=9606 GN=RAB2A PE=1 SV=1 5.38 3420 - 201732 - - - 2.5001 - 2.612 0.515 - 158.3 1 2 0 0.0047 15 0 0 0 8.50E+06 5.77E+06 - - - 4.0508 1 221125_WJC_METTL3_EV_vs_WT_F06.22170.22170.3 7.50E-11 35/124 K.VGGTNLGAPGAFGQSPFSQPPAPPHQNTFPPR.S sp|Q96I24|FUBP3_HUMAN 1 3227.5901 2.35 89367 22170 3 3227.596044 1076.8706 Far upstream element-binding protein 3 OS=Homo sapiens OX=9606 GN=FUBP3 PE=1 SV=2 9.73 3420.4 - 3.85E+06 - - - 1.8478 - 4.745 0.641 - 771.5 1 2 0 0.006 32 0 0 0 3.01E+08 1.28E+08 - - - 9.2672 1 221125_WJC_METTL3_EV_vs_WT_F06.22173.22173.3 2.31E-07 25/60 K.IQK[136.11]LLQDFFNGK[136.11]ELNK[136.11].S "sp|P54652|HSP72_HUMAN,sp|P11142|HSP7C_HUMAN,tr|E9PNE6|E9PNE6_HUMAN,tr|A8K7Q2|A8K7Q2_HUMAN,tr|E9PKE3|E9PKE3_HUMAN,tr|E9PN89|E9PN89_HUMAN" 6 1958.1051 0.15 89369 22173 3 1958.110231 653.709 Heat shock-related 70 kDa protein 2 OS=Homo sapiens OX=9606 GN=HSPA2 PE=1 SV=1 8.5 3420.7 - 1.63E+06 - - - 2.5959 - 4.58 0.595 - 980 1 2 2 0.0051 16 0 0 0 3.82E+06 2.55E+07 - - - 9.0767 0.9985 221125_WJC_METTL3_EV_vs_WT_F06.22174.22174.3 8.63E-08 21/80 R.K[136.11]IELFGR[166.11]PHNVQPNWITLGNQ.L sp|Q86U44|MTA70_HUMAN 1 2478.3251 0.001 89370 22174 3 2478.326598 827.1156 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 8.75 3420.8 - 5.43E+06 - - - 0.6117 - 3.763 0.532 - 509.8 1 1 0 0.0015 21 0 0 0 0.00E+00 9.60E+08 - - - 7.648 1 221125_WJC_METTL3_EV_vs_WT_F06.22178.22178.3 1.25E-10 24/76 K.GHPDLQGQPAEEIFESVGDR.E sp|P49257|LMAN1_HUMAN 1 2180.0134 1.69 89374 22178 3 2180.016366 727.6784 Protein ERGIC-53 OS=Homo sapiens OX=9606 GN=LMAN1 PE=1 SV=2 4.17 3421.2 - 1.14E+06 - - - 1.3491 - 4.366 0.67 - 715.6 1 2 0 0.0029 20 0 0 0 1.01E+08 5.96E+07 - - - 9.5846 1 221125_WJC_METTL3_EV_vs_WT_F06.22179.22179.3 1.84E-11 27/124 R.FSGFGSGAGGK[136.11]PLEGLSNGNNITSAPPFASAK[136.11].A "sp|Q9UKX7|NUP50_HUMAN,tr|B0QY21|B0QY21_HUMAN" 2 3052.5225 1.72 89375 22179 3 3052.538428 1018.5148 Nuclear pore complex protein Nup50 OS=Homo sapiens OX=9606 GN=NUP50 PE=1 SV=2 8.59 3421.4 - 981869 - - - 5.2134 - 4.343 0.694 - 357.5 1 2 0 0.0159 32 0 0 0 1.31E+08 7.62E+07 - - - 9.6516 1 221125_WJC_METTL3_EV_vs_WT_F06.22180.22180.3 5.44E-09 18/56 R.RDTFNHLTTWLEDAR.Q "sp|P61019|RAB2A_HUMAN,tr|H7C125|H7C125_HUMAN,tr|E9PKL7|E9PKL7_HUMAN" 3 1873.9071 0.44 89376 22180 3 1873.908026 625.643 Ras-related protein Rab-2A OS=Homo sapiens OX=9606 GN=RAB2A PE=1 SV=1 5.38 3421.5 - 822621 - - - 0.4888 - 3.459 0.554 - 506.8 1 2 0 0.0009 15 0 0 0 1.79E+07 4.05E+07 - - - 7.9545 0.9996 221125_WJC_METTL3_EV_vs_WT_F06.22184.22184.4 4.37E-05 13/90 K.IQKLLQDFFNGKELNK.S "sp|P54652|HSP72_HUMAN,sp|P11142|HSP7C_HUMAN,tr|E9PNE6|E9PNE6_HUMAN,tr|A8K7Q2|A8K7Q2_HUMAN,tr|E9PKE3|E9PKE3_HUMAN,tr|E9PN89|E9PN89_HUMAN" 6 1934.0625 0.12 89380 22184 4 1934.066285 484.5229 Heat shock-related 70 kDa protein 2 OS=Homo sapiens OX=9606 GN=HSPA2 PE=1 SV=1 8.5 3422 - 337056 - - - 1.9322 - 2.307 0.457 - 100.7 1 2 2 0.0037 16 0 0 0 4.19E+06 3.43E+07 - - - 3.4972 1 221125_WJC_METTL3_EV_vs_WT_F06.22186.22186.4 1.03E-07 28/186 K.VGGTNLGAPGAFGQSPFSQPPAPPHQNTFPPR.S sp|Q96I24|FUBP3_HUMAN 1 3227.5901 2.29 89381 22186 4 3227.595944 807.9048 Far upstream element-binding protein 3 OS=Homo sapiens OX=9606 GN=FUBP3 PE=1 SV=2 9.73 3422.2 - 7.68E+06 - - - 1.8168 - 4.167 0.531 - 179.6 1 2 0 0.0059 32 0 0 0 3.36E+08 1.47E+08 - - - 4.2771 1 221125_WJC_METTL3_EV_vs_WT_F06.22188.22188.4 8.29E-14 27/162 R.KVPGVTAIDLDEDTC[160.03]TFHIYGEDQDAVK.K "sp|Q06787|FMR1_HUMAN,tr|A0A087WY29|A0A087WY29_HUMAN,tr|R9WNI0|R9WNI0_HUMAN,tr|A8MQB8|A8MQB8_HUMAN,tr|A0A087WWR6|A0A087WWR6_HUMAN,tr|A0A087WXI3|A0A087WXI3_HUMAN,tr|Q8IXW7|Q8IXW7_HUMAN,tr|G3V0J0|G3V0J0_HUMAN" 8 3135.4707 2.66 89382 22188 4 3135.474498 784.8749 Synaptic functional regulator FMR1 OS=Homo sapiens OX=9606 GN=FMR1 PE=1 SV=1 4.09 3422.4 - 6.01E+06 - - - 1.2237 - 4.73 0.734 - 487.2 1 2 0 0.0038 28 0 0 0 7.26E+07 2.73E+07 - - - 6.0961 1 221125_WJC_METTL3_EV_vs_WT_F06.22189.22189.2 3.12E-14 29/36 K.SKELTTEIDNNIEQISSYK.S "sp|P13645|K1C10_HUMAN,tr|A0A1B0GVI3|A0A1B0GVI3_HUMAN" 2 2211.0907 999 89383 22189 2 2211.092283 1106.5526 "Keratin, type I cytoskeletal 10 OS=Homo sapiens OX=9606 GN=KRT10 PE=1 SV=6" 4.41 3422.6 - 2.47E+06 - - - 0.7281 - 5.151 0.696 - 3270.8 1 2 1 0.0016 19 0 0 0 3.30E+08 0.00E+00 - - - 8.2112 1 221125_WJC_METTL3_EV_vs_WT_F06.22190.22190.3 1.27E-08 19/84 K.GYLTDLNSMIPTHGGDINDIKK.A sp|O94906|PRP6_HUMAN 1 2401.1948 1.61 89384 22190 3 2401.193367 801.4055 Pre-mRNA-processing factor 6 OS=Homo sapiens OX=9606 GN=PRPF6 PE=1 SV=1 5.3 3422.7 - 1.85E+06 - - - -0.5805 - 3.734 0.563 - 253.4 1 2 0 -0.0014 22 0 0 0 2.22E+07 1.38E+07 - - - 7.94 0.9999 221125_WJC_METTL3_EV_vs_WT_F06.22191.22191.4 2.69E-07 21/150 K.LASSLPDNK[136.11]QEENTALNK[136.11]DFLPIEIR[166.11].G sp|Q5VT06|CE350_HUMAN 1 2980.5716 2.13 89385 22191 4 2980.570534 746.1502 Centrosome-associated protein 350 OS=Homo sapiens OX=9606 GN=CEP350 PE=1 SV=1 4.51 3422.8 - 1.52E+06 - - - -0.353 - 3.386 0.505 - 178.4 1 2 2 -0.0011 26 0 0 0 3.93E+07 1.85E+07 - - - 4.0059 1 221125_WJC_METTL3_EV_vs_WT_F06.22192.22192.3 1.63E-13 21/104 R.GSSGGGC[160.03]FGGSSGGYGGLGGFGGGSFR.G "sp|P13645|K1C10_HUMAN,tr|A0A1B0GVI3|A0A1B0GVI3_HUMAN" 2 2341.9771 429.7 89386 22192 3 2341.974971 781.6663 "Keratin, type I cytoskeletal 10 OS=Homo sapiens OX=9606 GN=KRT10 PE=1 SV=6" 8.22 3422.9 - 1.33E+06 - - - -0.8907 - 4.204 0.709 - 203.5 1 2 0 -0.0021 27 0 0 0 3.32E+09 7.72E+06 - - - 9.7479 1 221125_WJC_METTL3_EV_vs_WT_F06.22194.22194.3 2.26E-11 15/104 K.EYSNHSIFSPSLEEQTAVSGAVNDSIK[136.11].A "sp|Q03112|MECOM_HUMAN,tr|E7EUL6|E7EUL6_HUMAN,tr|A0A0C3SFZ7|A0A0C3SFZ7_HUMAN" 3 2916.3869 1.6 89388 22194 3 2916.383302 973.1362 Histone-lysine N-methyltransferase MECOM OS=Homo sapiens OX=9606 GN=MECOM PE=1 SV=3 4.4 3423.2 - 535150 - - - -1.2203 - 3.644 0.703 - 157.2 1 2 0 -0.0036 27 0 0 0 9.06E+06 5.68E+06 - - - 9.3517 1 221125_WJC_METTL3_EV_vs_WT_F06.22197.22197.4 2.56E-06 21/108 K.KISSIQSIVPALEIANAHR.K "sp|P10809|CH60_HUMAN,tr|A0A7I2V2X6|A0A7I2V2X6_HUMAN,tr|A0A7I2YQK6|A0A7I2YQK6_HUMAN,tr|A0A7I2V599|A0A7I2V599_HUMAN,tr|A0A7I2YQ71|A0A7I2YQ71_HUMAN,tr|A0A7I2V5M1|A0A7I2V5M1_HUMAN,tr|A0A7I2V5K3|A0A7I2V5K3_HUMAN,tr|A0A7I2V369|A0A7I2V369_HUMAN" 8 2046.1586 1.33 89390 22197 4 2046.159913 512.5469 "60 kDa heat shock protein, mitochondrial OS=Homo sapiens OX=9606 GN=HSPD1 PE=1 SV=2" 8.75 3423.5 - 5.77E+06 - - - 0.6549 - 3.419 0.611 - 355.8 1 2 0 0.0013 19 0 0 0 6.47E+08 4.86E+08 - - - 4.9596 0.9999 221125_WJC_METTL3_EV_vs_WT_F06.22200.22200.4 1.18E-06 17/186 R.FSGFGSGAGGKPLEGLSNGNNITSAPPFASAK.A "sp|Q9UKX7|NUP50_HUMAN,tr|B0QY21|B0QY21_HUMAN" 2 3036.4941 2.08 89392 22200 4 3036.498944 760.1308 Nuclear pore complex protein Nup50 OS=Homo sapiens OX=9606 GN=NUP50 PE=1 SV=2 8.59 3423.9 - 773331 - - - 1.5907 - 2.831 0.474 - 81.9 1 2 0 0.0048 32 0 0 0 1.63E+07 7.82E+06 - - - 3.6646 1 221125_WJC_METTL3_EV_vs_WT_F06.22201.22201.3 3.98E-11 18/72 K.SKELTTEIDNNIEQISSYK.S "sp|P13645|K1C10_HUMAN,tr|A0A1B0GVI3|A0A1B0GVI3_HUMAN" 2 2211.0907 750.45 89393 22201 3 2211.0896 738.0375 "Keratin, type I cytoskeletal 10 OS=Homo sapiens OX=9606 GN=KRT10 PE=1 SV=6" 4.41 3423.9 - 2.21E+08 - - - -0.4853 - 3.649 0.645 - 350 1 2 1 -0.0011 19 0 0 0 8.01E+09 1.07E+07 - - - 8.911 1 221125_WJC_METTL3_EV_vs_WT_F06.22202.22202.4 1.55E-13 27/162 R.K[136.11]VPGVTAIDLDEDTC[160.03]TFHIYGEDQDAVK[136.11].K "sp|Q06787|FMR1_HUMAN,tr|A0A087WY29|A0A087WY29_HUMAN,tr|R9WNI0|R9WNI0_HUMAN,tr|A8MQB8|A8MQB8_HUMAN,tr|A0A087WWR6|A0A087WWR6_HUMAN,tr|A0A087WXI3|A0A087WXI3_HUMAN,tr|Q8IXW7|Q8IXW7_HUMAN,tr|G3V0J0|G3V0J0_HUMAN" 8 3151.4991 2.66 89394 22202 4 3151.499585 788.882 Synaptic functional regulator FMR1 OS=Homo sapiens OX=9606 GN=FMR1 PE=1 SV=1 4.09 3424 - 4.60E+06 - - - 0.1663 - 4.313 0.696 - 587 1 2 0 0.0005 28 0 0 0 7.26E+07 2.73E+07 - - - 5.7376 1 221125_WJC_METTL3_EV_vs_WT_F06.22203.22203.3 2.47E-09 27/76 K.GHPDLQGQPAEEIFESVGDR[166.11].E sp|P49257|LMAN1_HUMAN 1 2190.0217 1.74 89395 22203 3 2190.023669 731.0145 Protein ERGIC-53 OS=Homo sapiens OX=9606 GN=LMAN1 PE=1 SV=2 4.17 3424.1 - 1.18E+06 - - - 0.9014 - 4.583 0.663 - 994 1 2 0 0.002 20 0 0 0 8.94E+07 5.13E+07 - - - 9.6245 1 221125_WJC_METTL3_EV_vs_WT_F06.22206.22206.3 2.55E-11 18/72 K.EK[136.11]VNVDIINFGEEEVNTEK[136.11].L "sp|P55036|PSMD4_HUMAN,sp|A2A3N6|PIPSL_HUMAN,tr|A6PVX3|A6PVX3_HUMAN,tr|Q5VWC4|Q5VWC4_HUMAN" 4 2221.1085 1.18 89396 22206 3 2221.102698 741.3768 26S proteasome non-ATPase regulatory subunit 4 OS=Homo sapiens OX=9606 GN=PSMD4 PE=1 SV=1 4.14 3424.5 - 3.29E+06 - - - -2.6158 - 3.789 0.65 - 552.4 1 2 1 -0.0058 19 0 0 0 1.17E+08 9.91E+07 - - - 9.058 1 221125_WJC_METTL3_EV_vs_WT_F06.22207.22207.3 1.80E-10 28/124 K.VGGTNLGAPGAFGQSPFSQPPAPPHQNTFPPR[166.11].S sp|Q96I24|FUBP3_HUMAN 1 3237.5984 2.36 89397 22207 3 3237.593763 1080.2067 Far upstream element-binding protein 3 OS=Homo sapiens OX=9606 GN=FUBP3 PE=1 SV=2 9.73 3424.6 - 2.27E+06 - - - -1.4168 - 4.189 0.632 - 448.3 1 2 0 -0.0046 32 0 0 0 3.06E+08 1.30E+08 - - - 8.8805 1 221125_WJC_METTL3_EV_vs_WT_F06.22209.22209.2 2.48E-08 27/52 R.GSSGGGC[160.03]FGGSSGGYGGLGGFGGGSFR.G "sp|P13645|K1C10_HUMAN,tr|A0A1B0GVI3|A0A1B0GVI3_HUMAN" 2 2341.9771 999 89399 22209 2 2341.975565 1171.9958 "Keratin, type I cytoskeletal 10 OS=Homo sapiens OX=9606 GN=KRT10 PE=1 SV=6" 8.22 3424.8 - 2.20E+06 - - - -0.6371 - 5.01 0.762 - 1676 1 2 0 -0.0015 27 0 0 0 7.63E+08 0.00E+00 - - - 8.6305 1 221125_WJC_METTL3_EV_vs_WT_F06.22210.22210.4 2.79E-07 18/150 K.DGQMLPGEDEPLHALVTANTMENVKK.A "sp|Q15637|SF01_HUMAN,tr|A0A7P0T9U7|A0A7P0T9U7_HUMAN" 2 2836.3735 1.21 89400 22210 4 2836.373044 710.1007 Splicing factor 1 OS=Homo sapiens OX=9606 GN=SF1 PE=1 SV=4 4.5 3424.9 - 1.38E+06 - - - -0.1713 - 2.884 0.511 - 153.7 1 2 0 -0.0005 26 0 0 0 5.62E+07 4.66E+07 - - - 4.0077 0.9999 221125_WJC_METTL3_EV_vs_WT_F06.22215.22215.4 1.61E-09 17/108 K.SKELTTEIDNNIEQISSYK.S "sp|P13645|K1C10_HUMAN,tr|A0A1B0GVI3|A0A1B0GVI3_HUMAN" 2 2211.0907 10.45 89403 22215 4 2211.091619 553.7799 "Keratin, type I cytoskeletal 10 OS=Homo sapiens OX=9606 GN=KRT10 PE=1 SV=6" 4.41 3425.6 - 1.83E+06 - - - 0.4278 - 3.587 0.556 - 194.2 1 2 1 0.0009 19 0 0 0 1.70E+07 1.63E+06 - - - 4.4973 0.9776 221125_WJC_METTL3_EV_vs_WT_F06.22218.22218.4 0.00291 13/84 K.QKVDSLLENLEKIEK.E "sp|P0DMR1|HNRC4_HUMAN,sp|P07910|HNRPC_HUMAN,sp|O60812|HNRC1_HUMAN,sp|B2RXH8|HNRC2_HUMAN,sp|B7ZW38|HNRC3_HUMAN,tr|B4DY08|B4DY08_HUMAN,tr|G3V5V7|G3V5V7_HUMAN,tr|B2R5W2|B2R5W2_HUMAN,tr|G3V4C1|G3V4C1_HUMAN,tr|A0A0G2JPF8|A0A0G2JPF8_HUMAN,tr|A0A0G2JNQ3|A0A0G2JNQ3_HUMAN,tr|G3V576|G3V576_HUMAN,tr|G3V2D6|G3V2D6_HUMAN,tr|G3V4W0|G3V4W0_HUMAN,tr|G3V2Q1|G3V2Q1_HUMAN" 15 1784.9884 1.42 89405 22218 4 1784.985714 447.2544 Heterogeneous nuclear ribonucleoprotein C-like 4 OS=Homo sapiens OX=9606 GN=HNRNPCL4 PE=3 SV=1 4.87 3425.9 - 482200 - - - -1.4936 - 2.735 0.207 - 131 1 2 2 -0.0027 15 0 0 0 9.13E+06 6.44E+06 - - - 1.387 1 221125_WJC_METTL3_EV_vs_WT_F06.22219.22219.4 3.58E-10 19/150 K.DGQMLPGEDEPLHALVTANTMENVK[136.11]K[136.11].A "sp|Q15637|SF01_HUMAN,tr|A0A7P0T9U7|A0A7P0T9U7_HUMAN" 2 2852.4019 1.21 89406 22219 4 2852.401783 714.1078 Splicing factor 1 OS=Homo sapiens OX=9606 GN=SF1 PE=1 SV=4 4.5 3426 - 1.46E+06 - - - -0.0515 - 3.56 0.601 - 182 1 2 0 -0.0001 26 0 0 0 5.62E+07 4.66E+07 - - - 4.8576 0.9999 221125_WJC_METTL3_EV_vs_WT_F06.22223.22223.4 0.000155 10/132 K.GSWDDLVEGHNELSVSTLTADK[136.11]R[166.11].D sp|Q8N3C0|ASCC3_HUMAN 1 2546.2368 11.84 89408 22223 4 2546.232688 637.5665 Activating signal cointegrator 1 complex subunit 3 OS=Homo sapiens OX=9606 GN=ASCC3 PE=1 SV=3 4.43 3426.5 - 781614 - - - -1.6071 - 2.37 0.456 - 56.3 1 2 0 -0.0041 23 0 0 0 1.79E+08 1.51E+07 - - - 3.4735 1 221125_WJC_METTL3_EV_vs_WT_F06.22234.22234.4 1.68E-07 30/186 K.VGGTNLGAPGAFGQSPFSQPPAPPHQNTFPPR[166.11].S sp|Q96I24|FUBP3_HUMAN 1 3237.5984 2.29 89415 22234 4 3237.595755 810.4069 Far upstream element-binding protein 3 OS=Homo sapiens OX=9606 GN=FUBP3 PE=1 SV=2 9.73 3427.8 - 4.99E+06 - - - -0.8015 - 4.513 0.535 - 331.2 1 2 0 -0.0026 32 0 0 0 3.41E+08 1.49E+08 - - - 4.3369 1 221125_WJC_METTL3_EV_vs_WT_F06.22237.22237.3 2.61E-12 27/92 R.EQINQLTSYIDASNVYGSTEHEAR.S sp|Q92626|PXDN_HUMAN 1 2724.2627 1.72 89417 22237 3 2724.248876 909.0948 Peroxidasin homolog OS=Homo sapiens OX=9606 GN=PXDN PE=1 SV=2 4.4 3428.1 - 827214 - - - -5.0806 - 4.919 0.688 - 752.4 1 2 0 -0.0138 24 0 0 0 1.56E+07 9.05E+06 - - - 9.9068 1 221125_WJC_METTL3_EV_vs_WT_F06.22239.22239.3 7.95E-14 29/104 K.HLNEEELGQLQTQASDTSVVLSMDNNR.Y sp|Q8N1N4|K2C78_HUMAN 1 3027.4204 59.79 89419 22239 3 3027.415242 1010.1474 "Keratin, type II cytoskeletal 78 OS=Homo sapiens OX=9606 GN=KRT78 PE=1 SV=2" 4.17 3428.3 - 1.37E+06 - - - -1.6896 - 5.347 0.739 - 978 1 2 0 -0.0051 27 0 0 0 7.62E+07 1.27E+06 - - - 10.6348 0.9791 221125_WJC_METTL3_EV_vs_WT_F06.22242.22242.2 0.00698 18-Nov V.PALEIANAHR[166.11].K "sp|P10809|CH60_HUMAN,tr|A0A7I2V2X6|A0A7I2V2X6_HUMAN,tr|A0A7I2YQK6|A0A7I2YQK6_HUMAN,tr|A0A7I2V599|A0A7I2V599_HUMAN,tr|A0A7I2YQ71|A0A7I2YQ71_HUMAN,tr|A0A7I2V5M1|A0A7I2V5M1_HUMAN,tr|A0A7I2V5K3|A0A7I2V5K3_HUMAN,tr|A0A7I2V369|A0A7I2V369_HUMAN" 8 1100.5966 1.93 89420 22242 2 1100.596484 551.3056 "60 kDa heat shock protein, mitochondrial OS=Homo sapiens OX=9606 GN=HSPD1 PE=1 SV=2" 7.18 3428.7 - 446460 - - - -0.1163 - 2.575 0.229 - 476.2 1 1 0 -0.0001 10 0 0 0 5.53E+07 2.86E+07 - - - 3.3725 0.9999 221125_WJC_METTL3_EV_vs_WT_F06.22248.22248.3 7.84E-06 14/64 R.AETEC[160.03]QNTEYQQLLDIK.L "sp|P13645|K1C10_HUMAN,tr|A0A1B0GVI3|A0A1B0GVI3_HUMAN" 2 2081.9576 779.16 89424 22248 3 2081.963899 694.9931 "Keratin, type I cytoskeletal 10 OS=Homo sapiens OX=9606 GN=KRT10 PE=1 SV=6" 4 3429.3 - 1.86E+06 - - - 3.0495 - 2.68 0.556 - 285.2 1 2 0 0.0063 17 0 0 0 2.17E+08 2.78E+05 - - - 7.2276 1 221125_WJC_METTL3_EV_vs_WT_F06.22260.22260.3 1.26E-12 26/72 K.K[136.11]ISSIQSIVPALEIANAHR[166.11].K "sp|P10809|CH60_HUMAN,tr|A0A7I2V2X6|A0A7I2V2X6_HUMAN,tr|A0A7I2YQK6|A0A7I2YQK6_HUMAN,tr|A0A7I2V599|A0A7I2V599_HUMAN,tr|A0A7I2YQ71|A0A7I2YQ71_HUMAN,tr|A0A7I2V5M1|A0A7I2V5M1_HUMAN,tr|A0A7I2V5K3|A0A7I2V5K3_HUMAN,tr|A0A7I2V369|A0A7I2V369_HUMAN" 8 2064.181 1.45 89431 22260 3 2064.177922 689.0676 "60 kDa heat shock protein, mitochondrial OS=Homo sapiens OX=9606 GN=HSPD1 PE=1 SV=2" 8.75 3430.8 - 5.40E+06 - - - -1.512 - 4.597 0.683 - 951.6 1 2 0 -0.0031 19 0 0 0 3.40E+08 2.34E+08 - - - 9.9015 0.9998 221125_WJC_METTL3_EV_vs_WT_F06.22262.22262.3 1.15E-06 15/100 R.SWSEESLKPSDNEQGLPVFSGSPPMK.S "sp|Q6W2J9|BCOR_HUMAN,tr|H7BZ37|H7BZ37_HUMAN,tr|H7C2V9|H7C2V9_HUMAN,tr|H7BYY2|H7BYY2_HUMAN,tr|H7C231|H7C231_HUMAN" 5 2832.3276 47.49 89432 22262 3 2832.317758 945.1165 BCL-6 corepressor OS=Homo sapiens OX=9606 GN=BCOR PE=1 SV=1 4.41 3431 - 637495 - - - -3.4837 - 2.373 0.512 - 130.9 1 2 0 -0.0099 26 0 0 0 2.16E+07 4.55E+05 - - - 6.2337 0.9998 221125_WJC_METTL3_EV_vs_WT_F06.22263.22263.4 8.12E-05 16/114 K.K[136.11]HEALMSDLSAYGSSIQALR[166.11].E "sp|Q13813|SPTN1_HUMAN,tr|A0A0D9SF54|A0A0D9SF54_HUMAN,tr|A0A0D9SGF6|A0A0D9SGF6_HUMAN" 3 2194.1171 1.84 89433 22263 4 2194.112709 549.5366 "Spectrin alpha chain, non-erythrocytic 1 OS=Homo sapiens OX=9606 GN=SPTAN1 PE=1 SV=3" 6.75 3431.1 - 473398 - - - -2.0117 - 2.701 0.399 - 170.7 1 2 0 -0.0044 20 0 0 0 1.26E+07 6.86E+06 - - - 3.0299 0.9905 221125_WJC_METTL3_EV_vs_WT_F06.22264.22264.4 1.28E-08 19/192 R.LASLMNLGMSSSLNQQGAHSALSSASTSSHNLQ.S "sp|P43243|MATR3_HUMAN,tr|D6RBS2|D6RBS2_HUMAN,tr|A8MXP9|A8MXP9_HUMAN,tr|D6R991|D6R991_HUMAN,tr|D6REK4|D6REK4_HUMAN,tr|A0A0R4J2E8|A0A0R4J2E8_HUMAN,tr|D6RCM3|D6RCM3_HUMAN,tr|D6R8Z5|D6R8Z5_HUMAN,tr|D6REM6|D6REM6_HUMAN" 9 3328.5776 - 89434 22264 4 3328.568425 833.1517 Matrin-3 OS=Homo sapiens OX=9606 GN=MATR3 PE=1 SV=2 6.92 3431.3 - 1.52E+06 - - - -2.757 - 4.063 0.501 - 166.5 1 1 0 -0.0092 33 0 0 0 - - - - - 4.0048 1 221125_WJC_METTL3_EV_vs_WT_F06.22269.22269.4 1.26E-19 35/162 R.TEVSFTLNEDLANIHDIGGKPASVSAPR.E sp|P13984|T2FB_HUMAN 1 2937.4832 1.35 89437 22269 4 2937.485845 735.3781 General transcription factor IIF subunit 2 OS=Homo sapiens OX=9606 GN=GTF2F2 PE=1 SV=2 4.75 3431.9 - 1.89E+06 - - - 0.8953 - 5.919 0.719 - 703.9 1 2 0 0.0026 28 0 0 0 6.75E+07 5.00E+07 - - - 6.0355 1 221125_WJC_METTL3_EV_vs_WT_F06.22271.22271.3 6.80E-10 20/64 K.QNHESVQWC[160.03]YDNFINYR[166.11].S sp|O43143|DHX15_HUMAN 1 2281.9839 1.02 89439 22271 3 2281.982629 761.6686 Pre-mRNA-splicing factor ATP-dependent RNA helicase DHX15 OS=Homo sapiens OX=9606 GN=DHX15 PE=1 SV=2 5.32 3432.1 - 1.85E+06 - - - -0.5438 - 3.575 0.663 - 603 1 2 0 -0.0012 17 0 0 0 3.78E+07 3.70E+07 - - - 9.1499 1 221125_WJC_METTL3_EV_vs_WT_F06.22275.22275.3 1.37E-12 23/128 R.LASLMNLGMSSSLNQQGAHSALSSASTSSHNLQ.S "sp|P43243|MATR3_HUMAN,tr|D6RBS2|D6RBS2_HUMAN,tr|A8MXP9|A8MXP9_HUMAN,tr|D6R991|D6R991_HUMAN,tr|D6REK4|D6REK4_HUMAN,tr|A0A0R4J2E8|A0A0R4J2E8_HUMAN,tr|D6RCM3|D6RCM3_HUMAN,tr|D6R8Z5|D6R8Z5_HUMAN,tr|D6REM6|D6REM6_HUMAN" 9 3328.5776 - 89442 22275 3 3328.575915 1110.5331 Matrin-3 OS=Homo sapiens OX=9606 GN=MATR3 PE=1 SV=2 6.92 3432.6 - 1.80E+06 - - - -0.5068 - 4.469 0.588 - 411.7 1 1 0 -0.0017 33 0 0 0 - - - - - 8.5396 1 221125_WJC_METTL3_EV_vs_WT_F06.22277.22277.2 1.19E-11 22/32 R.AETEC[160.03]QNTEYQQLLDIK.L "sp|P13645|K1C10_HUMAN,tr|A0A1B0GVI3|A0A1B0GVI3_HUMAN" 2 2081.9576 999 89443 22277 2 2081.955049 1041.9861 "Keratin, type I cytoskeletal 10 OS=Homo sapiens OX=9606 GN=KRT10 PE=1 SV=6" 4 3432.8 - 3.86E+06 - - - -1.2013 - 4.282 0.718 - 1916.9 1 2 0 -0.0025 17 0 0 0 1.04E+08 0.00E+00 - - - 7.9191 1 221125_WJC_METTL3_EV_vs_WT_F06.22279.22279.4 6.55E-08 32/162 R.TEVSFTLNEDLANIHDIGGK[136.11]PASVSAPR[166.11].E sp|P13984|T2FB_HUMAN 1 2955.5057 1.34 89445 22279 4 2955.503738 739.8837 General transcription factor IIF subunit 2 OS=Homo sapiens OX=9606 GN=GTF2F2 PE=1 SV=2 4.75 3433 - 4.42E+06 - - - -0.6588 - 5.311 0.627 - 435.1 1 2 0 -0.0019 28 0 0 0 6.73E+07 5.00E+07 - - - 5.2013 1 221125_WJC_METTL3_EV_vs_WT_F06.22281.22281.3 1.01E-07 17/64 K.QNHESVQWC[160.03]YDNFINYR.S sp|O43143|DHX15_HUMAN 1 2271.9756 1.01 89447 22281 3 2271.977056 758.3325 Pre-mRNA-splicing factor ATP-dependent RNA helicase DHX15 OS=Homo sapiens OX=9606 GN=DHX15 PE=1 SV=2 5.32 3433.1 - 2.18E+06 - - - 0.6409 - 3.34 0.638 - 381.3 1 2 0 0.0015 17 0 0 0 3.72E+07 3.68E+07 - - - 8.6993 0.9999 221125_WJC_METTL3_EV_vs_WT_F06.22283.22283.4 7.17E-08 22/138 K.K[136.11]GVNLPGAAVDLPAVSEK[136.11]DIQDLK[136.11].F "sp|P14618|KPYM_HUMAN,tr|H3BQ34|H3BQ34_HUMAN,tr|B4DNK4|B4DNK4_HUMAN,tr|A0A804F6T5|A0A804F6T5_HUMAN,tr|H3BTN5|H3BTN5_HUMAN,tr|H3BR70|H3BR70_HUMAN,tr|A0A804F729|A0A804F729_HUMAN" 7 2500.3963 1.15 89449 22283 4 2500.396152 626.1064 Pyruvate kinase PKM OS=Homo sapiens OX=9606 GN=PKM PE=1 SV=4 4.68 3433.4 - 1.17E+06 - - - -0.0608 - 3.752 0.578 - 285.2 1 2 1 -0.0002 24 0 0 0 3.92E+07 3.41E+07 - - - 4.6813 0.9987 221125_WJC_METTL3_EV_vs_WT_F06.22293.22293.3 2.60E-07 25/116 S.SLTSFGTETSNSGTLPQSSAVGSAFTQDTR[166.11].S "sp|Q8ND56|LS14A_HUMAN,tr|A0A140TA76|A0A140TA76_HUMAN,tr|K7EMZ9|K7EMZ9_HUMAN" 3 3043.4246 0.63 89455 22293 3 3043.424553 1015.4821 Protein LSM14 homolog A OS=Homo sapiens OX=9606 GN=LSM14A PE=1 SV=3 4.37 3434.7 - 2.15E+06 - - - -0.0112 - 3.531 0.571 - 347.9 1 1 0 0 30 0 0 0 2.55E+07 4.06E+07 - - - 7.8085 1 221125_WJC_METTL3_EV_vs_WT_F06.22294.22294.3 4.08E-13 23/76 K.IDC[160.03]DNLEQYFIQQGGGPDKK.G "sp|Q92499|DDX1_HUMAN,tr|A0A7I2V2M5|A0A7I2V2M5_HUMAN,tr|A0A087X2G1|A0A087X2G1_HUMAN,tr|A0A7I2V430|A0A7I2V430_HUMAN,tr|A0A7I2V4F0|A0A7I2V4F0_HUMAN,tr|A0A087WZ71|A0A087WZ71_HUMAN,tr|A0A7I2YQ77|A0A7I2YQ77_HUMAN" 7 2324.0743 1.54 89456 22294 3 2324.079742 775.6987 ATP-dependent RNA helicase DDX1 OS=Homo sapiens OX=9606 GN=DDX1 PE=1 SV=2 4.23 3434.8 - 2.12E+06 - - - 2.3368 - 3.82 0.686 - 770.9 1 2 0 0.0054 20 0 0 0 3.84E+07 2.49E+07 - - - 9.4382 1 221125_WJC_METTL3_EV_vs_WT_F06.22300.22300.4 1.57E-11 18/96 K.KWDTC[160.03]APEVILHAVGGK.L "sp|O95861|BPNT1_HUMAN,tr|A6NF51|A6NF51_HUMAN" 2 1879.9615 1.65 89462 22300 4 1879.965497 470.9976 "3'(2'),5'-bisphosphate nucleotidase 1 OS=Homo sapiens OX=9606 GN=BPNT1 PE=1 SV=1" 6.74 3435.5 - 424802 - - - 2.1506 - 3.332 0.574 - 302 1 2 0 0.004 17 0 0 0 5.09E+06 3.08E+06 - - - 4.6389 0.9972 221125_WJC_METTL3_EV_vs_WT_F06.22306.22306.3 0.000371 Nov-76 R.IKDFLQGSSC[160.03]IAGIYNETTK.Q sp|P15924|DESP_HUMAN 1 2244.1096 16.46 89466 22306 3 2244.116116 749.0438 Desmoplakin OS=Homo sapiens OX=9606 GN=DSP PE=1 SV=3 6.06 3436.1 - 1.24E+06 - - - 2.8885 - 2.537 0.362 - 74.4 2 2 1 0.0065 20 0 0 0 1.27E+07 7.71E+05 - - - 4.6934 0.9992 221125_WJC_METTL3_EV_vs_WT_F06.22308.22308.4 0.00163 13/120 R.FQAMYTSHLFNLDPSDPNFK[136.11]K[136.11].T sp|Q9H501|ESF1_HUMAN 1 2515.2177 0.64 89468 22308 4 2515.216291 629.8117 ESF1 homolog OS=Homo sapiens OX=9606 GN=ESF1 PE=1 SV=1 6.75 3436.4 - 607677 - - - -0.5526 - 2.266 0.302 - 114.8 1 2 0 -0.0014 21 0 0 0 4.42E+06 6.93E+06 - - - 2.1247 1 221125_WJC_METTL3_EV_vs_WT_F06.22321.22321.4 5.74E-10 16/138 K.SENLGQGDKPDYFSSVATVVYLRK.E sp|P27694|RFA1_HUMAN 1 2672.3446 1.29 89477 22321 4 2672.338839 669.0934 Replication protein A 70 kDa DNA-binding subunit OS=Homo sapiens OX=9606 GN=RPA1 PE=1 SV=2 5.84 3438.1 - 777845 - - - -2.1543 - 3.1 0.615 - 196.9 1 2 0 -0.0058 24 0 0 0 2.84E+07 2.20E+07 - - - 4.9405 1 221125_WJC_METTL3_EV_vs_WT_F06.22322.22322.4 2.00E-10 28/174 R.VPLVAPEDLRDDIIENAPTTHTEEYSGEEK.T "sp|O14744|ANM5_HUMAN,tr|G3V580|G3V580_HUMAN,tr|G3V2X6|G3V2X6_HUMAN,tr|G3V5L5|G3V5L5_HUMAN,tr|H0YJX6|H0YJX6_HUMAN" 5 3366.6103 2.41 89478 22322 4 3366.613607 842.6599 Protein arginine N-methyltransferase 5 OS=Homo sapiens OX=9606 GN=PRMT5 PE=1 SV=4 4.05 3438.2 - 3.19E+06 - - - 0.9746 - 4.437 0.658 - 321.4 1 2 1 0.0033 30 0 0 0 2.60E+08 1.08E+08 - - - 5.4083 0.9999 221125_WJC_METTL3_EV_vs_WT_F06.22329.22329.4 5.09E-10 20/102 K.EQGYDPFKEDLNHLVGYK.G sp|Q9NV35|NUD15_HUMAN 1 2151.0273 1.63 89483 22329 4 2151.028074 538.7641 Nucleotide triphosphate diphosphatase NUDT15 OS=Homo sapiens OX=9606 GN=NUDT15 PE=1 SV=1 4.75 3439.1 - 855440 - - - 0.3673 - 3.511 0.603 - 288.6 1 2 1 0.0008 18 0 0 0 1.77E+07 1.09E+07 - - - 4.9045 1 221125_WJC_METTL3_EV_vs_WT_F06.22330.22330.4 6.18E-12 36/192 K.PAVFSTSWAPVPSQSSVVYHPYGPQPHLGADTR.Y sp|P31274|HXC9_HUMAN 1 3534.7321 2.89 89484 22330 4 3534.738496 884.6903 Homeobox protein Hox-C9 OS=Homo sapiens OX=9606 GN=HOXC9 PE=1 SV=3 7.32 3439.3 - 1.47E+06 - - - 1.8228 - 5.613 0.658 - 636.3 1 1 0 0.0064 33 0 0 0 1.53E+07 5.30E+06 - - - 5.469 0.9998 221125_WJC_METTL3_EV_vs_WT_F06.22331.22331.3 4.23E-05 21/116 R.VLSAMINSNDDNGVLAGNWSGTYTGGRDPR.S "sp|Q08188|TGM3_HUMAN,tr|A0A494C0J7|A0A494C0J7_HUMAN" 2 3136.4632 999 89485 22331 3 3136.456951 1046.495 Protein-glutamine gamma-glutamyltransferase E OS=Homo sapiens OX=9606 GN=TGM3 PE=1 SV=4 4.43 3439.4 - 1.08E+06 - - - -2 - 2.506 0.556 - 151.1 1 2 1 -0.0063 30 0 0 0 4.95E+06 0.00E+00 - - - 6.8507 0.9909 221125_WJC_METTL3_EV_vs_WT_F06.22332.22332.4 1.92E-08 18/120 K.DFDFESANAQFNKEEIDREFH.N "sp|Q8ND56|LS14A_HUMAN,tr|A0A140TA76|A0A140TA76_HUMAN,tr|K7EMZ9|K7EMZ9_HUMAN" 3 2587.1252 2.27 89486 22332 4 2587.12434 647.7886 Protein LSM14 homolog A OS=Homo sapiens OX=9606 GN=LSM14A PE=1 SV=3 4.19 3439.5 - 900895 - - - -0.3173 - 3.332 0.557 - 105.1 1 1 2 -0.0008 21 0 0 0 1.25E+07 5.49E+06 - - - 4.4718 0.9996 221125_WJC_METTL3_EV_vs_WT_F06.22335.22335.3 5.80E-05 9/100 R.RQVGPPSFVPDSPSIPVGSPNFSSVK.Q "sp|Q8NEZ4|KMT2C_HUMAN,tr|A0A804HKS3|A0A804HKS3_HUMAN,tr|H7BY37|H7BY37_HUMAN,tr|A0A7P0TA60|A0A7P0TA60_HUMAN,tr|A0A804HIW6|A0A804HIW6_HUMAN,tr|A0A7P0TAI3|A0A7P0TAI3_HUMAN,tr|A0A7P0T9K8|A0A7P0T9K8_HUMAN,tr|A0A7P0TBM6|A0A7P0TBM6_HUMAN,tr|H0Y765|H0Y765_HUMAN,tr|H7C2V8|H7C2V8_HUMAN,tr|A0A804HJT1|A0A804HJT1_HUMAN,tr|A0A804HKW4|A0A804HKW4_HUMAN,tr|A0A804HLD4|A0A804HLD4_HUMAN,tr|A0A804HIK3|A0A804HIK3_HUMAN,tr|A0A804HI08|A0A804HI08_HUMAN,tr|A0A7P0T8F0|A0A7P0T8F0_HUMAN,tr|A0A804HK48|A0A804HK48_HUMAN" 17 2681.3813 -1 89489 22335 3 2681.387498 894.801 Histone-lysine N-methyltransferase 2C OS=Homo sapiens OX=9606 GN=KMT2C PE=1 SV=3 8.75 3439.9 - 258319 - - - 2.3055 - 2.067 0.41 - 40.5 1 2 0 0.0062 26 0 0 0 0.00E+00 0.00E+00 - - - 4.7799 1 221125_WJC_METTL3_EV_vs_WT_F06.22339.22339.3 3.01E-09 18/56 R.GFGFVTFDDHDPVDK[136.11].L "sp|P22626|ROA2_HUMAN,tr|A0A7I2V4N0|A0A7I2V4N0_HUMAN,tr|A0A024RA28|A0A024RA28_HUMAN,tr|A0A7I2V4N1|A0A7I2V4N1_HUMAN,tr|A0A7I2V4I6|A0A7I2V4I6_HUMAN,tr|A0A087WUI2|A0A087WUI2_HUMAN,tr|A0A7I2V4S4|A0A7I2V4S4_HUMAN,tr|A0A7I2V323|A0A7I2V323_HUMAN,tr|A0A7I2V3P1|A0A7I2V3P1_HUMAN,tr|A0A7I2V3P7|A0A7I2V3P7_HUMAN" 10 1702.7719 1.41 89491 22339 3 1702.772464 568.5979 Heterogeneous nuclear ribonucleoproteins A2\B1 OS=Homo sapiens OX=9606 GN=HNRNPA2B1 PE=1 SV=2 4.13 3440.4 - 783761 - - - 0.36 - 2.75 0.513 - 281.7 1 2 0 0.0006 15 0 0 0 1.70E+07 1.21E+07 - - - 6.8989 1 221125_WJC_METTL3_EV_vs_WT_F06.22342.22342.4 2.40E-12 16/138 K.SENLGQGDK[136.11]PDYFSSVATVVYLR[166.11]K[136.11].E sp|P27694|RFA1_HUMAN 1 2698.3813 1.42 89494 22342 4 2698.386087 675.6026 Replication protein A 70 kDa DNA-binding subunit OS=Homo sapiens OX=9606 GN=RPA1 PE=1 SV=2 5.84 3440.7 - 1.29E+06 - - - 1.7866 - 3.258 0.666 - 154.1 1 2 0 0.0048 24 0 0 0 2.04E+07 1.44E+07 - - - 5.4006 1 221125_WJC_METTL3_EV_vs_WT_F06.22346.22346.3 2.71E-10 18/92 K.LEFFGFEDHETGGDEGGSGSSNYK[136.11].L sp|Q7Z5K2|WAPL_HUMAN 1 2573.071 0.48 89498 22346 3 2573.070124 858.6976 Wings apart-like protein homolog OS=Homo sapiens OX=9606 GN=WAPL PE=1 SV=1 4.08 3441.2 - 460534 - - - -0.3428 - 3.432 0.684 - 262.4 1 2 0 -0.0009 24 0 0 0 2.15E+06 4.44E+06 - - - 9.0298 1 221125_WJC_METTL3_EV_vs_WT_F06.22352.22352.3 1.48E-12 31/80 R.AEGEWEDQEALDYFSDKESGK.Q "sp|Q9NYF8|BCLF1_HUMAN,tr|E9PKI6|E9PKI6_HUMAN,tr|A0A1W2PQ43|A0A1W2PQ43_HUMAN,tr|E9PK91|E9PK91_HUMAN,tr|E9PK09|E9PK09_HUMAN,tr|E9PQN2|E9PQN2_HUMAN" 6 2432.0292 2.08 89502 22352 3 2432.032393 811.6837 Bcl-2-associated transcription factor 1 OS=Homo sapiens OX=9606 GN=BCLAF1 PE=1 SV=2 3.89 3441.9 - 8.31E+06 - - - 1.315 - 5.256 0.751 - 1342.9 1 2 1 0.0032 21 0 0 0 1.13E+08 5.43E+07 - - - 10.8903 1 221125_WJC_METTL3_EV_vs_WT_F06.22353.22353.3 6.57E-12 36/84 K.GPAVGIDLGTTYSC[160.03]VGVFQHGK[136.11].V "sp|P11142|HSP7C_HUMAN,tr|E9PQQ4|E9PQQ4_HUMAN,tr|E9PNE6|E9PNE6_HUMAN,tr|E9PKE3|E9PKE3_HUMAN,tr|E9PLF4|E9PLF4_HUMAN,tr|E9PI65|E9PI65_HUMAN,tr|E9PK54|E9PK54_HUMAN,tr|E9PN25|E9PN25_HUMAN,tr|E9PPY6|E9PPY6_HUMAN,tr|E9PQK7|E9PQK7_HUMAN" 10 2270.1245 0.12 89503 22353 3 2270.126675 757.7154 Heat shock cognate 71 kDa protein OS=Homo sapiens OX=9606 GN=HSPA8 PE=1 SV=1 6.73 3442 - 4.45E+06 - - - 0.9568 - 4.815 0.683 - 1447.3 1 2 0 0.0022 22 0 0 0 7.62E+06 6.37E+07 - - - 9.8805 1 221125_WJC_METTL3_EV_vs_WT_F06.22354.22354.3 1.08E-06 17/56 R.GFGFVTFDDHDPVDK.L "sp|P22626|ROA2_HUMAN,tr|A0A7I2V4N0|A0A7I2V4N0_HUMAN,tr|A0A024RA28|A0A024RA28_HUMAN,tr|A0A7I2V4N1|A0A7I2V4N1_HUMAN,tr|A0A7I2V4I6|A0A7I2V4I6_HUMAN,tr|A0A087WUI2|A0A087WUI2_HUMAN,tr|A0A7I2V4S4|A0A7I2V4S4_HUMAN,tr|A0A7I2V323|A0A7I2V323_HUMAN,tr|A0A7I2V3P1|A0A7I2V3P1_HUMAN,tr|A0A7I2V3P7|A0A7I2V3P7_HUMAN" 10 1694.7577 1.41 89504 22354 3 1694.758957 565.9265 Heterogeneous nuclear ribonucleoproteins A2\B1 OS=Homo sapiens OX=9606 GN=HNRNPA2B1 PE=1 SV=2 4.13 3442.1 - 1.24E+06 - - - 0.7706 - 2.841 0.642 - 201.6 1 2 0 0.0013 15 0 0 0 1.70E+07 1.21E+07 - - - 8.4219 1 221125_WJC_METTL3_EV_vs_WT_F06.22355.22355.4 1.01E-15 36/204 R.YGPQYGHPPPPPPPPEYGPHADSPVLMVYGLDQSK.M "sp|P14866|HNRPL_HUMAN,tr|A0A3B3ITJ4|A0A3B3ITJ4_HUMAN,tr|M0QXS5|M0QXS5_HUMAN" 3 3783.8032 1.55 89505 22355 4 3783.809485 946.9581 Heterogeneous nuclear ribonucleoprotein L OS=Homo sapiens OX=9606 GN=HNRNPL PE=1 SV=2 5.21 3442.2 - 1.20E+06 - - - 1.6692 - 6.308 0.682 - 859.7 1 2 0 0.0063 35 0 0 0 1.71E+08 1.11E+08 - - - 5.7064 0.9999 221125_WJC_METTL3_EV_vs_WT_F06.22356.22356.4 1.21E-07 17/102 K.EQGYDPFK[136.11]EDLNHLVGYK[136.11].G sp|Q9NV35|NUD15_HUMAN 1 2167.0557 1.63 89506 22356 4 2167.057433 542.7712 Nucleotide triphosphate diphosphatase NUDT15 OS=Homo sapiens OX=9606 GN=NUDT15 PE=1 SV=1 4.75 3442.3 - 1.19E+06 - - - 0.8066 - 3.087 0.585 - 200.6 1 2 1 0.0017 18 0 0 0 1.77E+07 1.09E+07 - - - 4.7035 1 221125_WJC_METTL3_EV_vs_WT_F06.22357.22357.3 4.12E-08 30/100 K.QSHAASAAPQASSPPDYTMAWAEYYR.Q sp|Q96I24|FUBP3_HUMAN 1 2855.2609 1.84 89507 22357 3 2855.26087 952.7609 Far upstream element-binding protein 3 OS=Homo sapiens OX=9606 GN=FUBP3 PE=1 SV=2 5.32 3442.4 - 1.17E+06 - - - -0.0256 - 5.032 0.683 - 803.3 1 2 0 -0.0001 26 0 0 0 1.25E+08 6.76E+07 - - - 9.8722 1 221125_WJC_METTL3_EV_vs_WT_F06.22360.22360.3 2.43E-14 23/96 K.DR[166.11]PQEADGIDSVIVVDNVPQVGPDR[166.11].L "sp|P55884|EIF3B_HUMAN,tr|C9JZG1|C9JZG1_HUMAN" 2 2709.3473 1.26 89510 22360 3 2709.344732 904.123 Eukaryotic translation initiation factor 3 subunit B OS=Homo sapiens OX=9606 GN=EIF3B PE=1 SV=3 3.9 3442.8 - 813550 - - - -0.9393 - 4.313 0.598 - 388.1 1 2 0 -0.0025 25 0 0 0 4.56E+07 3.62E+07 - - - 8.5691 1 221125_WJC_METTL3_EV_vs_WT_F06.22364.22364.4 1.04E-12 22/174 R.VPLVAPEDLR[166.11]DDIIENAPTTHTEEYSGEEK[136.11].T "sp|O14744|ANM5_HUMAN,tr|G3V580|G3V580_HUMAN,tr|G3V2X6|G3V2X6_HUMAN,tr|G3V5L5|G3V5L5_HUMAN,tr|H0YJX6|H0YJX6_HUMAN" 5 3384.6328 2.9 89512 22364 4 3384.634498 847.1655 Protein arginine N-methyltransferase 5 OS=Homo sapiens OX=9606 GN=PRMT5 PE=1 SV=4 4.05 3443.3 - 2.39E+06 - - - 0.5029 - 3.994 0.638 - 201.5 1 2 1 0.0017 30 0 0 0 2.57E+08 8.87E+07 - - - 5.2024 0.8911 221125_WJC_METTL3_EV_vs_WT_F06.22367.22367.3 0.546 Nov-56 K.K[136.11]LLHHLSDLALTLPT.D "sp|Q86U44|MTA70_HUMAN,tr|B4E349|B4E349_HUMAN,tr|F5H6D8|F5H6D8_HUMAN,tr|H0YFV6|H0YFV6_HUMAN,tr|B4DTN4|B4DTN4_HUMAN" 5 1678.9861 0.01 89515 22367 3 1678.985438 560.6693 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 6.92 3443.7 - 395901 - - - -0.4193 - 2.116 0.243 - 101.3 1 1 0 -0.0007 15 0 0 0 1.71E+05 2.44E+07 - - - 3.2048 0.9997 221125_WJC_METTL3_EV_vs_WT_F06.22368.22368.4 7.89E-05 Dec-84 K.FGHEFLEFEFR[166.11]PDGK[136.11].L "sp|Q96A72|MGN2_HUMAN,sp|P61326|MGN_HUMAN,tr|F5H6N1|F5H6N1_HUMAN" 3 1871.8962 2.84 89516 22368 4 1871.901965 468.9813 Protein mago nashi homolog 2 OS=Homo sapiens OX=9606 GN=MAGOHB PE=1 SV=1 4.83 3443.8 - 343013 - - - 3.1043 - 2.362 0.437 - 145.2 1 2 0 0.0058 15 0 0 0 2.06E+07 7.26E+06 - - - 3.3356 0.999 221125_WJC_METTL3_EV_vs_WT_F06.22375.22375.4 0.00019 Nov-96 K.NFGEDMDDERLKDLFGK.F "sp|Q9H361|PABP3_HUMAN,sp|P11940|PABP1_HUMAN,tr|A0A7I2YQE4|A0A7I2YQE4_HUMAN,tr|A0A7I2V649|A0A7I2V649_HUMAN,tr|H0YAR2|H0YAR2_HUMAN,tr|E7ERJ7|E7ERJ7_HUMAN,tr|H0YBN4|H0YBN4_HUMAN,tr|A0A087WTT1|A0A087WTT1_HUMAN,tr|A0A7I2YQ90|A0A7I2YQ90_HUMAN,tr|A0A7I2V4N4|A0A7I2V4N4_HUMAN,tr|E7EQV3|E7EQV3_HUMAN" 11 2027.9259 1.34 89521 22375 4 2027.929314 507.9887 Polyadenylate-binding protein 3 OS=Homo sapiens OX=9606 GN=PABPC3 PE=1 SV=2 4.23 3444.7 - 367965 - - - 1.7052 - 2.058 0.387 - 126.2 1 2 2 0.0035 17 0 0 0 4.02E+06 3.00E+06 - - - 2.8441 1 221125_WJC_METTL3_EV_vs_WT_F06.22378.22378.3 2.65E-08 18/72 R.AETEC[160.03]QNTEYQQLLDIKIR.L "sp|P13645|K1C10_HUMAN,tr|A0A1B0GVI3|A0A1B0GVI3_HUMAN" 2 2351.1427 999 89522 22378 3 2351.148131 784.7215 "Keratin, type I cytoskeletal 10 OS=Homo sapiens OX=9606 GN=KRT10 PE=1 SV=6" 4.41 3445.1 - 630358 - - - 2.2993 - 3.554 0.642 - 386.4 1 2 1 0.0054 19 0 0 0 9.28E+06 0.00E+00 - - - 8.8116 0.9999 221125_WJC_METTL3_EV_vs_WT_F06.22380.22380.3 0.000849 13/72 R.GLLQDDAHPTLVTYADHSK[136.11].L "sp|Q86U44|MTA70_HUMAN,tr|F5H6D8|F5H6D8_HUMAN,tr|H0YFV6|H0YFV6_HUMAN,tr|B4DTN4|B4DTN4_HUMAN" 4 2088.0367 0.06 89524 22380 3 2088.037386 697.0195 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 5.13 3445.4 - 516947 - - - 0.3127 - 2.601 0.364 - 179.9 1 2 0 0.0007 19 0 0 0 7.02E+05 1.18E+07 - - - 4.9465 0.9995 221125_WJC_METTL3_EV_vs_WT_F06.22381.22381.4 6.91E-09 21/138 K.ALNEHHVNATLDLIEGSMTVC[160.03]TTK.K sp|Q13601|KRR1_HUMAN 1 2653.284 1.34 89525 22381 4 2654.285564 664.3283 KRR1 small subunit processome component homolog OS=Homo sapiens OX=9606 GN=KRR1 PE=1 SV=4 5.28 3445.5 - 304372 - - - 377.4858 - 3.374 0.58 - 208.3 1 2 0 1.0016 24 0 0 0 7.99E+06 5.96E+06 - - - 4.3872 1 221125_WJC_METTL3_EV_vs_WT_F06.22382.22382.3 1.48E-10 16/56 R.R[166.11]EEQIVQLLNSVQAK[136.11].N "sp|Q9H2U1|DHX36_HUMAN,tr|E7EWK3|E7EWK3_HUMAN" 2 1771.9911 1.44 89526 22382 3 1771.991749 591.671 ATP-dependent DNA\RNA helicase DHX36 OS=Homo sapiens OX=9606 GN=DHX36 PE=1 SV=2 6.14 3445.7 - 268968 - - - 0.3567 - 3.428 0.582 - 449.8 1 2 0 0.0006 15 0 0 0 6.97E+06 4.84E+06 - - - 8.2432 0.9999 221125_WJC_METTL3_EV_vs_WT_F06.22386.22386.4 1.08E-07 22/126 K.LNC[160.03]FLEQDLKLDIPTGTTPQRK.S "sp|P52732|KIF11_HUMAN,tr|A0A7I2V3A9|A0A7I2V3A9_HUMAN" 2 2586.3476 3.89 89527 22386 4 2586.353312 647.5942 Kinesin-like protein KIF11 OS=Homo sapiens OX=9606 GN=KIF11 PE=1 SV=2 6.11 3446.3 - 956911 - - - 2.219 - 3.47 0.559 - 330 1 2 1 0.0057 22 0 0 0 6.35E+07 1.63E+07 - - - 4.497 1 221125_WJC_METTL3_EV_vs_WT_F06.22393.22393.3 2.69E-05 17/68 K.YVHYEIDAC[160.03]MDSEAPGSK[136.11].D "sp|Q86U44|MTA70_HUMAN,tr|H0YFV6|H0YFV6_HUMAN" 2 2078.8805 0 89532 22393 3 2078.884104 693.9674 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 4.31 3447.1 - 1.12E+06 - - - 1.7375 - 3.527 0.511 - 310.7 1 2 0 0.0036 18 0 0 0 9.07E+04 5.62E+07 - - - 7.3748 1 221125_WJC_METTL3_EV_vs_WT_F06.22394.22394.3 2.05E-14 18/120 R.GSEGK[136.11]PSLTLPASAPGPEEALTTVTVAPAPR[166.11].R sp|P48634|PRC2A_HUMAN 1 3018.5993 1.25 89533 22394 3 3018.60424 1007.207 Protein PRRC2A OS=Homo sapiens OX=9606 GN=PRRC2A PE=1 SV=3 4.79 3447.3 - 467142 - - - 1.6528 - 3.824 0.706 - 276.7 1 2 0 0.005 31 0 0 0 3.10E+08 2.48E+08 - - - 9.4957 1 221125_WJC_METTL3_EV_vs_WT_F06.22395.22395.3 4.84E-12 14/96 K.LVQDVANNTNEEAGDGTTTATVLAR.S "sp|P10809|CH60_HUMAN,tr|C9JL25|C9JL25_HUMAN,tr|A0A7I2V2X6|A0A7I2V2X6_HUMAN,tr|A0A7I2YQK6|A0A7I2YQK6_HUMAN,tr|A0A7I2V599|A0A7I2V599_HUMAN,tr|E7EXB4|E7EXB4_HUMAN,tr|A0A7I2YQ71|A0A7I2YQ71_HUMAN,tr|E7ESH4|E7ESH4_HUMAN,tr|A0A7I2V5M1|A0A7I2V5M1_HUMAN,tr|A0A7I2V5K3|A0A7I2V5K3_HUMAN,tr|A0A7I2V369|A0A7I2V369_HUMAN" 11 2559.2413 1.02 89534 22395 3 2559.246579 854.0877 "60 kDa heat shock protein, mitochondrial OS=Homo sapiens OX=9606 GN=HSPD1 PE=1 SV=2" 3.92 3447.4 - 439882 - - - 2.0811 - 3.109 0.63 - 198.1 1 2 0 0.0053 25 0 0 0 8.05E+06 7.88E+06 - - - 8.172 1 221125_WJC_METTL3_EV_vs_WT_F06.22406.22406.4 1.72E-06 16/108 R.GLLQDDAHPTLVTYADHSK[136.11].L "sp|Q86U44|MTA70_HUMAN,tr|F5H6D8|F5H6D8_HUMAN,tr|H0YFV6|H0YFV6_HUMAN,tr|B4DTN4|B4DTN4_HUMAN" 4 2088.0367 0.01 89542 22406 4 2088.037592 523.0165 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 5.13 3448.7 - 1.28E+06 - - - 0.4114 - 2.834 0.52 - 227.6 1 2 0 0.0009 19 0 0 0 2.84E+05 3.40E+07 - - - 4.1042 0.9417 221125_WJC_METTL3_EV_vs_WT_F06.22408.22408.4 0.000417 17/120 R.K[136.11]IELFGR[166.11]PHNVQPNWITLGNQ.L sp|Q86U44|MTA70_HUMAN 1 2478.3251 0.02 89543 22408 4 2478.325658 620.5885 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 8.75 3448.9 - 2.50E+06 - - - 0.2324 - 3.121 0.315 - 166.9 1 1 0 0.0006 21 0 0 0 4.67E+07 2.90E+09 - - - 2.3439 1 221125_WJC_METTL3_EV_vs_WT_F06.22410.22410.4 1.56E-10 16/138 K.AVGYSC[160.03]MPSNKDEDGLVVLVFNKK.E sp|Q7Z3B4|NUP54_HUMAN 1 2669.3193 2.55 89545 22410 4 2669.318356 668.3371 Nucleoporin p54 OS=Homo sapiens OX=9606 GN=NUP54 PE=1 SV=2 6.15 3449.1 - 1.13E+06 - - - -0.3574 - 3.2 0.644 - 137.2 1 2 1 -0.001 24 0 0 0 5.38E+07 2.11E+07 - - - 5.2044 1 221125_WJC_METTL3_EV_vs_WT_F06.22412.22412.3 8.74E-14 23/120 R.GSEGKPSLTLPASAPGPEEALTTVTVAPAPR.R sp|P48634|PRC2A_HUMAN 1 3000.5768 1.25 89547 22412 3 3000.578202 1001.1995 Protein PRRC2A OS=Homo sapiens OX=9606 GN=PRRC2A PE=1 SV=3 4.79 3449.4 - 803228 - - - 0.4736 - 4.091 0.709 - 455.6 1 2 0 0.0014 31 0 0 0 3.10E+08 2.48E+08 - - - 9.6854 0.9999 221125_WJC_METTL3_EV_vs_WT_F06.22418.22418.3 0.139 16/60 K.K[136.11]VSQEILELLNTTTAK[136.11].E "sp|Q86U44|MTA70_HUMAN,tr|H0YFV6|H0YFV6_HUMAN" 2 1803.0324 0.01 89551 22418 3 1803.031499 602.0181 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 6.14 3450.2 - 1.02E+06 - - - -0.5164 - 2.774 0.388 - 288.3 1 2 0 -0.0009 16 0 0 0 1.96E+05 3.03E+07 - - - 5.4835 1 221125_WJC_METTL3_EV_vs_WT_F06.22423.22423.3 6.70E-13 37/124 K.VGGTNLGAPGAFGQSPFSQPPAPPHQNTFPPR.S sp|Q96I24|FUBP3_HUMAN 1 3227.5901 2.32 89554 22423 3 3227.593323 1076.8706 Far upstream element-binding protein 3 OS=Homo sapiens OX=9606 GN=FUBP3 PE=1 SV=2 9.73 3450.8 - 3.61E+06 - - - 1.0048 - 5.094 0.662 - 815.4 1 2 0 0.0032 32 0 0 0 1.64E+08 7.04E+07 - - - 9.6653 1 221125_WJC_METTL3_EV_vs_WT_F06.22425.22425.4 3.48E-06 25/150 R.TGHILHPEYLQPLPSTPVSPIELDAK.K sp|Q96F45|ZN503_HUMAN 1 2851.512 1.83 89556 22425 4 2851.514802 713.8853 Zinc finger protein 503 OS=Homo sapiens OX=9606 GN=ZNF503 PE=1 SV=1 5.26 3451 - 1.10E+06 - - - 0.984 - 3.845 0.56 - 343 1 2 0 0.0028 26 0 0 0 5.78E+07 3.16E+07 - - - 4.5243 0.9469 221125_WJC_METTL3_EV_vs_WT_F06.22428.22428.2 0.00119 18-Nov R.EC[160.03]LNLWGYER[166.11].V sp|Q86U44|MTA70_HUMAN 1 1348.6109 0 89557 22428 2 1349.608798 675.3127 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 4.53 3451.4 - 2.74E+06 - - - 739.9147 - 2.047 0.527 - 574.4 1 2 0 0.9979 10 0 0 0 3.47E+05 8.37E+07 - - - 4.6197 0.9999 221125_WJC_METTL3_EV_vs_WT_F06.22429.22429.4 1.59E-10 22/126 K.LNC[160.03]FLEQDLK[136.11]LDIPTGTTPQR[166.11]K[136.11].S "sp|P52732|KIF11_HUMAN,tr|A0A7I2V3A9|A0A7I2V3A9_HUMAN" 2 2612.3842 3.84 89558 22429 4 2612.384657 654.1033 Kinesin-like protein KIF11 OS=Homo sapiens OX=9606 GN=KIF11 PE=1 SV=2 6.11 3451.5 - 1.08E+06 - - - 0.1585 - 3.693 0.597 - 327.7 1 2 1 0.0004 22 0 0 0 6.75E+07 1.76E+07 - - - 4.8496 1 221125_WJC_METTL3_EV_vs_WT_F06.22433.22433.3 3.03E-16 18/132 R.AGAGAPVVGSGSSGGGNAFTGLGPVSTLPSLHGK[136.11].Q "sp|Q9NNW5|WDR6_HUMAN,tr|E9PDU5|E9PDU5_HUMAN,tr|A0A087X295|A0A087X295_HUMAN" 3 2971.5243 1.12 89562 22433 3 2971.533045 991.5154 WD repeat-containing protein 6 OS=Homo sapiens OX=9606 GN=WDR6 PE=1 SV=1 8.8 3452 - 388575 - - - 2.9436 - 3.752 0.703 - 181.1 1 2 0 0.0087 34 0 0 0 1.30E+07 1.16E+07 - - - 9.4174 1 221125_WJC_METTL3_EV_vs_WT_F06.22436.22436.4 5.45E-11 28/186 K.VGGTNLGAPGAFGQSPFSQPPAPPHQNTFPPR.S sp|Q96I24|FUBP3_HUMAN 1 3227.5901 2.29 89563 22436 4 3227.591293 807.9048 Far upstream element-binding protein 3 OS=Homo sapiens OX=9606 GN=FUBP3 PE=1 SV=2 9.73 3452.4 - 6.34E+06 - - - 0.3758 - 4.511 0.581 - 256.3 1 2 0 0.0012 32 0 0 0 1.62E+08 7.08E+07 - - - 4.7376 1 221125_WJC_METTL3_EV_vs_WT_F06.22437.22437.3 1.64E-12 23/108 K.NPFSSASGGFGSTATSNTSNLFGNSGAK.T "sp|P35658|NU214_HUMAN,tr|A0A494C0Y1|A0A494C0Y1_HUMAN,tr|A0A0A0MSW3|A0A0A0MSW3_HUMAN,tr|B7ZAV2|B7ZAV2_HUMAN,tr|A0A494C1F2|A0A494C1F2_HUMAN,tr|H0Y837|H0Y837_HUMAN" 6 2664.2052 1.68 89564 22437 3 2664.206445 889.0757 Nuclear pore complex protein Nup214 OS=Homo sapiens OX=9606 GN=NUP214 PE=1 SV=2 8.75 3452.5 - 2.48E+06 - - - 0.4666 - 4.582 0.605 - 567.1 1 2 0 0.0012 28 0 0 0 9.88E+07 5.88E+07 - - - 8.7867 0.9937 221125_WJC_METTL3_EV_vs_WT_F06.22438.22438.3 9.54E-06 15/80 R.K[136.11]IELFGR[166.11]PHNVQPNWITLGNQ.L sp|Q86U44|MTA70_HUMAN 1 2478.3251 0.001 89565 22438 3 2478.325129 827.1156 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 8.75 3452.6 - 1.10E+06 - - - 0.019 - 2.689 0.43 - 240.3 1 1 0 0 21 0 0 0 0.00E+00 3.27E+07 - - - 5.7056 1 221125_WJC_METTL3_EV_vs_WT_F06.22444.22444.3 2.33E-13 27/112 K.QAQVATGGGPGAPPGSQPDYSAAWAEYYR.Q "sp|Q92945|FUBP2_HUMAN,tr|M0R263|M0R263_HUMAN,tr|M0R3J3|M0R3J3_HUMAN,tr|M0R0C6|M0R0C6_HUMAN,tr|M0R251|M0R251_HUMAN" 5 2951.3475 1.22 89569 22444 3 2951.345951 984.7898 Far upstream element-binding protein 2 OS=Homo sapiens OX=9606 GN=KHSRP PE=1 SV=4 4.37 3453.4 - 1.41E+06 - - - -0.5079 - 4.756 0.708 - 470.8 1 2 0 -0.0015 29 0 0 0 9.03E+07 7.37E+07 - - - 10.0207 1 221125_WJC_METTL3_EV_vs_WT_F06.22446.22446.3 3.01E-18 27/108 K.NPFSSASGGFGSTATSNTSNLFGNSGAK[136.11].T "sp|P35658|NU214_HUMAN,tr|A0A494C0Y1|A0A494C0Y1_HUMAN,tr|A0A0A0MSW3|A0A0A0MSW3_HUMAN,tr|B7ZAV2|B7ZAV2_HUMAN,tr|A0A494C1F2|A0A494C1F2_HUMAN,tr|H0Y837|H0Y837_HUMAN" 6 2672.2194 1.68 89571 22446 3 2672.21502 891.7471 Nuclear pore complex protein Nup214 OS=Homo sapiens OX=9606 GN=NUP214 PE=1 SV=2 8.75 3453.7 - 1.47E+06 - - - -1.6398 - 4.69 0.729 - 753.8 1 2 0 -0.0044 28 0 0 0 9.88E+07 5.88E+07 - - - 10.2219 0.9985 221125_WJC_METTL3_EV_vs_WT_F06.22449.22449.4 0.00112 10/114 R.FK[136.11]K[136.11]EDEIPETVSLEMLDAAK[136.11].N "sp|Q96A26|F162A_HUMAN,tr|F8W7Q4|F8W7Q4_HUMAN,tr|E9PH05|E9PH05_HUMAN" 3 2316.1985 1.42 89574 22449 4 2316.197541 580.0569 Protein FAM162A OS=Homo sapiens OX=9606 GN=FAM162A PE=1 SV=2 4.36 3454.1 - 417030 - - - -0.4209 - 2.104 0.345 - 85.9 1 2 1 -0.001 20 0 0 0 6.89E+06 4.85E+06 - - - 2.4773 1 221125_WJC_METTL3_EV_vs_WT_F06.22452.22452.3 3.04E-15 33/112 K.QAQVATGGGPGAPPGSQPDYSAAWAEYYR[166.11].Q "sp|Q92945|FUBP2_HUMAN,tr|M0R263|M0R263_HUMAN,tr|M0R3J3|M0R3J3_HUMAN,tr|M0R0C6|M0R0C6_HUMAN,tr|M0R251|M0R251_HUMAN" 5 2961.3557 1.22 89575 22452 3 2961.353793 988.1258 Far upstream element-binding protein 2 OS=Homo sapiens OX=9606 GN=KHSRP PE=1 SV=4 4.37 3454.5 - 1.25E+06 - - - -0.6507 - 5.071 0.713 - 741.8 1 2 0 -0.0019 29 0 0 0 9.03E+07 7.39E+07 - - - 10.2239 1 221125_WJC_METTL3_EV_vs_WT_F06.22453.22453.4 9.05E-11 23/186 K.LVSQTGPVHAPIFTMSVEVDGNSFEASGPSKK.T sp|Q12906|ILF3_HUMAN 1 3315.6445 1.39 89576 22453 4 3315.650082 829.9184 Interleukin enhancer-binding factor 3 OS=Homo sapiens OX=9606 GN=ILF3 PE=1 SV=3 5.45 3454.6 - 900340 - - - 1.6706 - 4.425 0.565 - 331 1 2 0 0.0055 32 0 0 0 1.24E+07 8.93E+06 - - - 4.5913 1 221125_WJC_METTL3_EV_vs_WT_F06.22454.22454.2 3.09E-06 15/32 R.ENSASQISQLEQQLSAK.N "sp|Q13948|CASP_HUMAN,sp|P39880|CUX1_HUMAN,tr|A0A2R8Y852|A0A2R8Y852_HUMAN,tr|A0A2R8YDI1|A0A2R8YDI1_HUMAN" 4 1859.9225 1.46 89577 22454 2 1859.924432 930.9685 Protein CASP OS=Homo sapiens OX=9606 GN=CUX1 PE=1 SV=2 4.53 3454.7 - 499503 - - - 1.0468 - 3.284 0.599 - 550.3 1 2 0 0.0019 17 0 0 0 1.45E+07 9.95E+06 - - - 6.388 0.9997 221125_WJC_METTL3_EV_vs_WT_F06.22456.22456.2 0.000507 16-Aug K.AAIDWFDGK[136.11].E "sp|P35637|FUS_HUMAN,sp|Q92804|RBP56_HUMAN,tr|H3BPE7|H3BPE7_HUMAN,tr|A0A075B7D9|A0A075B7D9_HUMAN" 4 1029.5011 1.28 89579 22456 2 1029.499359 515.7578 RNA-binding protein FUS OS=Homo sapiens OX=9606 GN=FUS PE=1 SV=1 4.21 3455 - 173354 - - - -1.6872 - 1.658 0.504 - 139 1 2 0 -0.0017 9 0 0 0 3.20E+06 2.50E+06 - - - 4.2258 1 221125_WJC_METTL3_EV_vs_WT_F06.22459.22459.2 2.19E-07 13/18 R.EC[160.03]LNLWGYER[166.11].V sp|Q86U44|MTA70_HUMAN 1 1348.6109 0 89580 22459 2 1348.612594 675.3127 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 4.53 3455.4 - 3.13E+06 - - - 1.2257 - 2.355 0.587 - 883.4 1 2 0 0.0017 10 0 0 0 3.47E+05 8.37E+07 - - - 5.7669 1 221125_WJC_METTL3_EV_vs_WT_F06.22460.22460.3 1.74E-08 30/124 K.VGGTNLGAPGAFGQSPFSQPPAPPHQNTFPPR[166.11].S sp|Q96I24|FUBP3_HUMAN 1 3237.5984 2.31 89581 22460 3 3237.597141 1080.2067 Far upstream element-binding protein 3 OS=Homo sapiens OX=9606 GN=FUBP3 PE=1 SV=2 9.73 3455.5 - 1.62E+06 - - - -0.3734 - 3.941 0.659 - 520.3 1 2 0 -0.0012 32 0 0 0 1.59E+08 6.87E+07 - - - 9.042 1 221125_WJC_METTL3_EV_vs_WT_F06.22461.22461.3 6.94E-07 16/64 R.ENSASQISQLEQQLSAK[136.11].N "sp|Q13948|CASP_HUMAN,sp|P39880|CUX1_HUMAN,tr|A0A2R8Y852|A0A2R8Y852_HUMAN,tr|A0A2R8YDI1|A0A2R8YDI1_HUMAN" 4 1867.9367 1.63 89582 22461 3 1867.937859 623.6528 Protein CASP OS=Homo sapiens OX=9606 GN=CUX1 PE=1 SV=2 4.53 3455.6 - 881725 - - - 0.6285 - 2.899 0.535 - 390.4 1 2 0 0.0012 17 0 0 0 2.29E+07 1.41E+07 - - - 7.1933 1 221125_WJC_METTL3_EV_vs_WT_F06.22462.22462.4 5.67E-10 21/180 R.GSEGK[136.11]PSLTLPASAPGPEEALTTVTVAPAPR[166.11].R sp|P48634|PRC2A_HUMAN 1 3018.5993 1.07 89583 22462 4 3018.600935 755.6571 Protein PRRC2A OS=Homo sapiens OX=9606 GN=PRRC2A PE=1 SV=3 4.79 3455.8 - 779259 - - - 0.5579 - 3.227 0.592 - 222.8 1 2 0 0.0017 31 0 0 0 6.41E+07 6.00E+07 - - - 4.7344 1 221125_WJC_METTL3_EV_vs_WT_F06.22463.22463.2 3.73E-09 15/32 R.ENSASQISQLEQQLSAK[136.11].N "sp|Q13948|CASP_HUMAN,sp|P39880|CUX1_HUMAN,tr|A0A2R8Y852|A0A2R8Y852_HUMAN,tr|A0A2R8YDI1|A0A2R8YDI1_HUMAN" 4 1867.9367 1.46 89584 22463 2 1867.940327 934.9756 Protein CASP OS=Homo sapiens OX=9606 GN=CUX1 PE=1 SV=2 4.53 3455.9 - 559878 - - - 1.9497 - 3.227 0.649 - 626.4 1 2 0 0.0036 17 0 0 0 1.45E+07 9.95E+06 - - - 6.7137 0.9998 221125_WJC_METTL3_EV_vs_WT_F06.22464.22464.4 0.000861 10/102 R.SPSELFAQHIVTIVHHVK.E "sp|Q9Y2W1|TR150_HUMAN,tr|A0A3B3ITZ9|A0A3B3ITZ9_HUMAN" 2 2041.1109 5.26 89585 22464 4 2041.114666 511.285 Thyroid hormone receptor-associated protein 3 OS=Homo sapiens OX=9606 GN=THRAP3 PE=1 SV=2 6.78 3456 - 293507 - - - 1.8475 - 2.012 0.394 - 72.4 1 2 0 0.0038 18 0 0 0 3.65E+07 6.95E+06 - - - 2.8938 1 221125_WJC_METTL3_EV_vs_WT_F06.22467.22467.4 9.25E-14 23/186 K.LVSQTGPVHAPIFTMSVEVDGNSFEASGPSK[136.11]K[136.11].T sp|Q12906|ILF3_HUMAN 1 3331.6729 1.36 89586 22467 4 3331.680613 833.9255 Interleukin enhancer-binding factor 3 OS=Homo sapiens OX=9606 GN=ILF3 PE=1 SV=3 5.45 3456.4 - 786728 - - - 2.3021 - 4.928 0.525 - 267.8 1 2 0 0.0077 32 0 0 0 2.58E+07 1.89E+07 - - - 4.275 1 221125_WJC_METTL3_EV_vs_WT_F06.22470.22470.4 1.21E-06 23/180 R.GSEGKPSLTLPASAPGPEEALTTVTVAPAPR.R sp|P48634|PRC2A_HUMAN 1 3000.5768 1.07 89589 22470 4 3000.580864 751.1515 Protein PRRC2A OS=Homo sapiens OX=9606 GN=PRRC2A PE=1 SV=3 4.79 3456.8 - 983555 - - - 1.3607 - 3.684 0.54 - 263.8 1 2 0 0.0041 31 0 0 0 6.43E+07 6.00E+07 - - - 4.3213 0.9999 221125_WJC_METTL3_EV_vs_WT_F06.22472.22472.4 2.15E-06 13/102 R.SDHLTVVNAFEGWEEARR.R "sp|Q9H2U1|DHX36_HUMAN,tr|E7EWK3|E7EWK3_HUMAN,tr|H7C514|H7C514_HUMAN" 3 2115.0134 0.9 89591 22472 4 2115.013024 529.7606 ATP-dependent DNA\RNA helicase DHX36 OS=Homo sapiens OX=9606 GN=DHX36 PE=1 SV=2 4.83 3457.1 - 390979 - - - -0.1617 - 2.315 0.442 - 128.5 1 2 0 -0.0003 18 0 0 0 7.54E+06 8.34E+06 - - - 3.3606 1 221125_WJC_METTL3_EV_vs_WT_F06.22478.22478.3 1.10E-17 31/92 K.AYHEQLSVAEITNAC[160.03]FEPANQMVK[136.11].C "sp|Q6PEY2|TBA3E_HUMAN,sp|P0DPH7|TBA3C_HUMAN,sp|Q71U36|TBA1A_HUMAN,sp|P0DPH8|TBA3D_HUMAN,sp|P68366|TBA4A_HUMAN,sp|P68363|TBA1B_HUMAN,tr|C9JDS9|C9JDS9_HUMAN" 7 2757.2982 0.59 89595 22478 3 2757.301435 920.1067 Tubulin alpha-3E chain OS=Homo sapiens OX=9606 GN=TUBA3E PE=1 SV=2 4.75 3457.8 - 893054 - - - 1.178 - 6.003 0.71 - 984.2 1 2 0 0.0032 24 0 0 0 3.54E+07 6.04E+07 - - - 10.6176 1 221125_WJC_METTL3_EV_vs_WT_F06.22479.22479.3 0.505 24/92 K.AYHEQLSVAEITNAC[160.03]FEPANQMVK.C "sp|Q6PEY2|TBA3E_HUMAN,sp|P0DPH7|TBA3C_HUMAN,sp|Q71U36|TBA1A_HUMAN,sp|P0DPH8|TBA3D_HUMAN,sp|P68366|TBA4A_HUMAN,sp|P68363|TBA1B_HUMAN,tr|C9JDS9|C9JDS9_HUMAN" 7 2749.284 0.59 89596 22479 3 2749.28788 917.4353 Tubulin alpha-3E chain OS=Homo sapiens OX=9606 GN=TUBA3E PE=1 SV=2 4.75 3458 - 414444 - - - 1.416 - 4.944 0.671 - 540 1 2 0 0.0039 24 0 0 0 3.54E+07 6.04E+07 - - - 9.7318 0.9754 221125_WJC_METTL3_EV_vs_WT_F06.22480.22480.4 0.000249 14/114 R.FKKEDEIPETVSLEMLDAAK.N "sp|Q96A26|F162A_HUMAN,tr|F8W7Q4|F8W7Q4_HUMAN,tr|E9PH05|E9PH05_HUMAN" 3 2292.1559 1.11 89597 22480 4 2292.166198 574.0463 Protein FAM162A OS=Homo sapiens OX=9606 GN=FAM162A PE=1 SV=2 4.36 3458.1 - 355161 - - - 4.4857 - 2.317 0.312 - 81.4 1 2 1 0.0103 20 0 0 0 5.06E+06 4.58E+06 - - - 2.2197 1 221125_WJC_METTL3_EV_vs_WT_F06.22482.22482.4 8.42E-09 32/186 K.VGGTNLGAPGAFGQSPFSQPPAPPHQNTFPPR[166.11].S sp|Q96I24|FUBP3_HUMAN 1 3237.5984 2.24 89598 22482 4 3237.603973 810.4069 Far upstream element-binding protein 3 OS=Homo sapiens OX=9606 GN=FUBP3 PE=1 SV=2 9.73 3458.3 - 1.79E+06 - - - 1.7368 - 4.538 0.536 - 392.8 1 2 0 0.0056 32 0 0 0 6.34E+08 2.83E+08 - - - 4.3465 0.9054 221125_WJC_METTL3_EV_vs_WT_F06.22485.22485.4 0.00392 14/114 R.K[136.11]IELFGR[166.11]PHNVQPNWITLGN.Q sp|Q86U44|MTA70_HUMAN 1 2350.2665 0.01 89600 22485 4 2350.268689 588.5739 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 8.75 3458.7 - 847016 - - - 0.9297 - 2.951 0.29 - 122 1 1 0 0.0022 20 0 0 0 1.52E+06 2.84E+08 - - - 2.1113 1 221125_WJC_METTL3_EV_vs_WT_F06.22490.22490.3 5.88E-10 19/92 K.NMTVEQLLTGSPTSPTVEPEK[136.11]PTR[166.11].E "sp|Q9C0C9|UBE2O_HUMAN,tr|K7ES11|K7ES11_HUMAN" 2 2629.3388 0.93 89603 22490 3 2629.338648 877.4535 (E3-independent) E2 ubiquitin-conjugating enzyme OS=Homo sapiens OX=9606 GN=UBE2O PE=1 SV=3 4.79 3459.3 - 644445 - - - -0.0586 - 4.023 0.631 - 326 1 2 0 -0.0002 24 0 0 0 1.65E+07 1.77E+07 - - - 8.8081 1 221125_WJC_METTL3_EV_vs_WT_F06.22499.22499.3 1.63E-13 22/80 R.LASYLDKVQALEEANNDLENK.L sp|P35527|K1C9_HUMAN 1 2376.1809 999 89610 22499 3 2376.18102 793.0676 "Keratin, type I cytoskeletal 9 OS=Homo sapiens OX=9606 GN=KRT9 PE=1 SV=3" 4.18 3460.5 - 1.89E+06 - - - 0.0568 - 4.558 0.682 - 601.2 1 2 1 0.0001 21 0 0 0 3.64E+07 0.00E+00 - - - 9.7802 1 221125_WJC_METTL3_EV_vs_WT_F06.22502.22502.3 5.78E-10 26/92 K.NMTVEQLLTGSPTSPTVEPEKPTR.E "sp|Q9C0C9|UBE2O_HUMAN,tr|K7ES11|K7ES11_HUMAN" 2 2611.3163 0.93 89613 22502 3 2611.318253 871.4461 (E3-independent) E2 ubiquitin-conjugating enzyme OS=Homo sapiens OX=9606 GN=UBE2O PE=1 SV=3 4.79 3460.9 - 819363 - - - 0.7356 - 4.686 0.603 - 714.4 1 2 0 0.0019 24 0 0 0 1.65E+07 1.77E+07 - - - 8.8498 0.9985 221125_WJC_METTL3_EV_vs_WT_F06.22503.22503.4 0.000178 16/162 K.SFEAPATINSASLHPEKEFLVAGGEDFK.L sp|Q9Y3F4|STRAP_HUMAN 1 2990.4662 1.04 89614 22503 4 2990.472842 748.6238 Serine-threonine kinase receptor-associated protein OS=Homo sapiens OX=9606 GN=STRAP PE=1 SV=1 4.57 3461 - 774442 - - - 2.2318 - 2.593 0.374 - 74.4 1 2 1 0.0067 28 0 0 0 1.43E+07 1.38E+07 - - - 2.7753 0.9591 221125_WJC_METTL3_EV_vs_WT_F06.22507.22507.3 0.00379 14/76 R.K[136.11]IELFGR[166.11]PHNVQPNWITLGN.Q sp|Q86U44|MTA70_HUMAN 1 2350.2665 0.001 89616 22507 3 2350.268215 784.4294 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 8.75 3461.6 - 1.59E+06 - - - 0.728 - 2.512 0.288 - 222.5 1 1 0 0.0017 20 0 0 0 0.00E+00 1.25E+08 - - - 3.985 1 221125_WJC_METTL3_EV_vs_WT_F06.22508.22508.4 0.000641 20/138 R.GSVTVLSGYAADEITHC[160.03]IR[166.11]PQDIK[136.11].E sp|Q6P6C2|ALKB5_HUMAN 1 2647.3395 1.13 89617 22508 4 2647.34225 662.8421 RNA demethylase ALKBH5 OS=Homo sapiens OX=9606 GN=ALKBH5 PE=1 SV=2 5.38 3461.7 - 1.09E+06 - - - 1.0497 - 3.834 0.487 - 253.5 1 2 0 0.0028 24 0 0 0 3.25E+07 2.87E+07 - - - 3.8954 0.9999 221125_WJC_METTL3_EV_vs_WT_F06.22515.22515.4 0.000429 Dec-90 R.DGQVHLFEHILNGYC[160.03]K.K "sp|Q15061|WDR43_HUMAN,tr|C9IZK7|C9IZK7_HUMAN" 2 1928.9203 0.88 89622 22515 4 1928.920372 483.2374 WD repeat-containing protein 43 OS=Homo sapiens OX=9606 GN=WDR43 PE=1 SV=3 5.99 3462.6 - 386867 - - - 0.0285 - 2.174 0.399 - 74.6 1 2 0 0.0001 16 0 0 0 1.03E+07 1.17E+07 - - - 2.9724 0.9992 221125_WJC_METTL3_EV_vs_WT_F06.22521.22521.4 0.0132 16/90 R.DGQVHLFEHILNGYC[160.03]K[136.11].K "sp|Q15061|WDR43_HUMAN,tr|C9IZK7|C9IZK7_HUMAN" 2 1936.9345 0.79 89626 22521 4 1936.932785 485.2409 WD repeat-containing protein 43 OS=Homo sapiens OX=9606 GN=WDR43 PE=1 SV=3 5.99 3463.4 - 919769 - - - -0.8942 - 2.486 0.299 - 143.5 1 2 0 -0.0017 16 0 0 0 1.03E+07 1.31E+07 - - - 2.1488 1 221125_WJC_METTL3_EV_vs_WT_F06.22524.22524.4 5.76E-06 20/138 R.GSVTVLSGYAADEITHC[160.03]IRPQDIK.E sp|Q6P6C2|ALKB5_HUMAN 1 2629.317 1.13 89627 22524 4 2629.320022 658.3365 RNA demethylase ALKBH5 OS=Homo sapiens OX=9606 GN=ALKBH5 PE=1 SV=2 5.38 3463.8 - 2.04E+06 - - - 1.149 - 3.575 0.557 - 291.7 1 2 0 0.003 24 0 0 0 3.25E+07 2.87E+07 - - - 4.4822 1 221125_WJC_METTL3_EV_vs_WT_F06.22525.22525.4 3.04E-16 24/156 K.HMDGGQIDGQEITATAVLAPWPRPPPR.R "sp|Q15287|RNPS1_HUMAN,tr|H3BMM9|H3BMM9_HUMAN,tr|H3BV80|H3BV80_HUMAN,tr|H3BTC0|H3BTC0_HUMAN,tr|H3BPG5|H3BPG5_HUMAN" 5 2909.4606 2.87 89628 22525 4 2909.459483 728.3724 RNA-binding protein with serine-rich domain 1 OS=Homo sapiens OX=9606 GN=RNPS1 PE=1 SV=1 5.38 3463.9 - 1.10E+06 - - - -0.3997 - 4.528 0.702 - 370.6 1 2 0 -0.0012 27 0 0 0 1.19E+08 4.16E+07 - - - 5.8084 1 221125_WJC_METTL3_EV_vs_WT_F06.22526.22526.4 1.31E-13 34/204 R.YGPQYGHPPPPPPPPEYGPHADSPVLMVYGLDQSK[136.11].M "sp|P14866|HNRPL_HUMAN,tr|A0A3B3ITJ4|A0A3B3ITJ4_HUMAN,tr|M0QXS5|M0QXS5_HUMAN" 3 3791.8174 2.23 89629 22526 4 3791.811904 948.9616 Heterogeneous nuclear ribonucleoprotein L OS=Homo sapiens OX=9606 GN=HNRNPL PE=1 SV=2 5.21 3464 - 5.77E+06 - - - -1.4413 - 6.197 0.606 - 636.6 1 2 0 -0.0055 35 0 0 0 1.71E+08 7.64E+07 - - - 5.0399 1 221125_WJC_METTL3_EV_vs_WT_F06.22528.22528.3 9.60E-08 16/48 R.KVESLQEEIAFLK.K "sp|P08670|VIME_HUMAN,tr|B0YJC5|B0YJC5_HUMAN,tr|B0YJC4|B0YJC4_HUMAN" 3 1532.845 1.92 89631 22528 3 1532.84436 511.9556 Vimentin OS=Homo sapiens OX=9606 GN=VIM PE=1 SV=4 4.79 3464.2 - 585811 - - - -0.424 - 3.242 0.509 - 608.9 1 2 0 -0.0006 13 0 0 0 3.59E+07 1.87E+07 - - - 7.4037 1 221125_WJC_METTL3_EV_vs_WT_F06.22529.22529.3 3.35E-09 15/48 R.K[136.11]VESLQEEIAFLK[136.11].K "sp|P08670|VIME_HUMAN,tr|B0YJC5|B0YJC5_HUMAN,tr|B0YJC4|B0YJC4_HUMAN" 3 1548.8734 1.93 89632 22529 3 1548.871539 517.2984 Vimentin OS=Homo sapiens OX=9606 GN=VIM PE=1 SV=4 4.79 3464.3 - 434788 - - - -1.208 - 3.07 0.565 - 331.5 1 2 0 -0.0019 13 0 0 0 3.59E+07 1.86E+07 - - - 7.8799 0.9999 221125_WJC_METTL3_EV_vs_WT_F06.22533.22533.4 1.28E-08 25/144 K.ELTTEIDNNIEQISSYKSEITELRR.N "sp|P13645|K1C10_HUMAN,tr|A0A1B0GVI3|A0A1B0GVI3_HUMAN" 2 2980.4989 90.25 89634 22533 4 2980.497419 746.132 "Keratin, type I cytoskeletal 10 OS=Homo sapiens OX=9606 GN=KRT10 PE=1 SV=6" 4.42 3464.8 - 2.61E+06 - - - -0.5053 - 4.064 0.579 - 303.8 1 2 1 -0.0015 25 0 0 0 3.26E+07 3.61E+05 - - - 4.7113 0.9998 221125_WJC_METTL3_EV_vs_WT_F06.22546.22546.2 0.000252 22-Oct K.DAGTIAGLNVLR.L "sp|P11142|HSP7C_HUMAN,tr|E9PQQ4|E9PQQ4_HUMAN,tr|E9PKE3|E9PKE3_HUMAN,tr|E9PN89|E9PN89_HUMAN,tr|E9PLF4|E9PLF4_HUMAN,tr|E9PI65|E9PI65_HUMAN,tr|E9PK54|E9PK54_HUMAN,tr|E9PQK7|E9PQK7_HUMAN" 8 1198.667 1.22 89643 22546 2 1198.664868 600.3408 Heat shock cognate 71 kDa protein OS=Homo sapiens OX=9606 GN=HSPA8 PE=1 SV=1 5.84 3466.4 - 1.82E+06 - - - -1.767 - 2.353 0.472 - 332.3 1 2 0 -0.0021 12 0 0 0 3.82E+07 3.14E+07 - - - 4.778 1 221125_WJC_METTL3_EV_vs_WT_F06.22556.22556.4 7.36E-09 25/126 R.SQDHFHVFVGDLSPEITTEDIK.A "sp|P31483|TIA1_HUMAN,tr|F8W8I6|F8W8I6_HUMAN,tr|E5RGV5|E5RGV5_HUMAN" 3 2513.2074 1.93 89647 22556 4 2513.206978 629.3091 Nucleolysin TIA-1 isoform p40 OS=Homo sapiens OX=9606 GN=TIA1 PE=1 SV=3 4.42 3467.8 - 5.64E+06 - - - -0.1814 - 4.096 0.627 - 535.8 1 2 0 -0.0005 22 0 0 0 1.87E+08 9.68E+07 - - - 5.1446 1 221125_WJC_METTL3_EV_vs_WT_F06.22557.22557.3 1.60E-13 29/84 R.SQDHFHVFVGDLSPEITTEDIK.A "sp|P31483|TIA1_HUMAN,tr|F8W8I6|F8W8I6_HUMAN,tr|E5RGV5|E5RGV5_HUMAN" 3 2513.2074 1.94 89648 22557 3 2513.204568 838.7431 Nucleolysin TIA-1 isoform p40 OS=Homo sapiens OX=9606 GN=TIA1 PE=1 SV=3 4.42 3467.9 - 1.95E+06 - - - -1.1404 - 4.961 0.681 - 1453.2 1 2 0 -0.0029 22 0 0 0 4.71E+07 2.42E+07 - - - 9.9288 0.9996 221125_WJC_METTL3_EV_vs_WT_F06.22558.22558.2 5.22E-05 22-Oct K.DAGTIAGLNVLR[166.11].L "sp|P11142|HSP7C_HUMAN,tr|E9PQQ4|E9PQQ4_HUMAN,tr|E9PKE3|E9PKE3_HUMAN,tr|E9PN89|E9PN89_HUMAN,tr|E9PLF4|E9PLF4_HUMAN,tr|E9PI65|E9PI65_HUMAN,tr|E9PK54|E9PK54_HUMAN,tr|E9PQK7|E9PQK7_HUMAN" 8 1208.6753 1.22 89649 22558 2 1208.672488 605.3449 Heat shock cognate 71 kDa protein OS=Homo sapiens OX=9606 GN=HSPA8 PE=1 SV=1 5.84 3468 - 1.04E+06 - - - -2.2901 - 2.282 0.459 - 319.6 1 2 0 -0.0028 12 0 0 0 3.83E+07 3.14E+07 - - - 4.6012 0.9855 221125_WJC_METTL3_EV_vs_WT_F06.22563.22563.3 1.96E-05 17/120 R.SDSPVPTAPTSGGPK[136.11]PSTASAVPELATDPEL.E "sp|Q86U44|MTA70_HUMAN,tr|B4E349|B4E349_HUMAN,tr|F5H6D8|F5H6D8_HUMAN,tr|B4DTN4|B4DTN4_HUMAN" 4 2983.4753 0.07 89651 22563 3 2983.467506 995.4991 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 3.92 3468.7 - 3.30E+06 - - - -2.6265 - 2.588 0.466 - 126 1 1 0 -0.0078 31 0 0 0 4.50E+06 6.90E+07 - - - 5.9209 1 221125_WJC_METTL3_EV_vs_WT_F06.22565.22565.3 3.35E-11 16/124 R.GGGGSFGYSYGGGSGGGFSASSLGGGFGGGSR.G sp|P35527|K1C9_HUMAN 1 2704.1538 999 89653 22565 3 2704.154373 902.3919 "Keratin, type I cytoskeletal 9 OS=Homo sapiens OX=9606 GN=KRT9 PE=1 SV=3" 8.59 3468.9 - 849389 - - - 0.199 - 2.75 0.724 - 142.3 1 2 0 0.0005 32 0 0 0 1.46E+07 0.00E+00 - - - 8.9391 1 221125_WJC_METTL3_EV_vs_WT_F06.22568.22568.3 7.14E-12 21/84 H.SALSSASTSSHNLQSIFNIGSR.G "sp|P43243|MATR3_HUMAN,tr|A8MXP9|A8MXP9_HUMAN,tr|D6R991|D6R991_HUMAN,tr|D6REK4|D6REK4_HUMAN,tr|A0A0R4J2E8|A0A0R4J2E8_HUMAN,tr|D6RCM3|D6RCM3_HUMAN,tr|D6R8Z5|D6R8Z5_HUMAN,tr|D6REM6|D6REM6_HUMAN" 8 2263.1193 1.34 89654 22568 3 2263.120628 755.3804 Matrin-3 OS=Homo sapiens OX=9606 GN=MATR3 PE=1 SV=2 9.49 3469.3 - 1.30E+07 - - - 0.5925 - 4.07 0.638 - 648.2 1 1 0 0.0013 22 0 0 0 1.17E+09 8.68E+08 - - - 8.9805 1 221125_WJC_METTL3_EV_vs_WT_F06.22570.22570.3 8.11E-10 22/64 R.VEAVNMAEGIIHDTETK[136.11].M "sp|P38646|GRP75_HUMAN,tr|A0A7I2V2S7|A0A7I2V2S7_HUMAN,tr|A0A7I2V2G2|A0A7I2V2G2_HUMAN,tr|A0A7I2V3F7|A0A7I2V3F7_HUMAN,tr|A0A7I2YQB2|A0A7I2YQB2_HUMAN,tr|D6RCD7|D6RCD7_HUMAN" 6 1863.9128 0.39 89656 22570 3 1863.909359 622.3115 "Stress-70 protein, mitochondrial OS=Homo sapiens OX=9606 GN=HSPA9 PE=1 SV=2" 4.4 3469.5 - 1.75E+06 - - - -1.8343 - 4.007 0.6 - 673.6 1 2 0 -0.0034 17 0 0 0 1.24E+07 3.19E+07 - - - 8.7351 0.9992 221125_WJC_METTL3_EV_vs_WT_F06.22571.22571.3 0.00263 13/56 K.TLNDMRQEYEQLIAK.N "sp|P35527|K1C9_HUMAN,tr|K7EQQ3|K7EQQ3_HUMAN" 2 1850.9196 18.54 89657 22571 3 1850.91793 617.9805 "Keratin, type I cytoskeletal 9 OS=Homo sapiens OX=9606 GN=KRT9 PE=1 SV=3" 4.68 3469.6 - 1.71E+06 - - - -0.9282 - 2.136 0.372 - 100.6 1 2 1 -0.0017 15 0 0 0 3.57E+07 1.93E+06 - - - 4.6673 1 221125_WJC_METTL3_EV_vs_WT_F06.22577.22577.3 1.70E-09 17/76 R.NTNGSQFFITTVPTPHLDGK.H sp|Q08752|PPID_HUMAN 1 2173.0804 2.5 89661 22577 3 2173.077332 725.3674 Peptidyl-prolyl cis-trans isomerase D OS=Homo sapiens OX=9606 GN=PPID PE=1 SV=3 6.74 3470.4 - 1.42E+06 - - - -1.404 - 3.483 0.593 - 261.6 1 2 0 -0.0031 20 0 0 0 5.02E+07 2.01E+07 - - - 8.1779 0.9925 221125_WJC_METTL3_EV_vs_WT_F06.22578.22578.4 1.62E-08 16/126 H.SALSSASTSSHNLQSIFNIGSR[166.11].G "sp|P43243|MATR3_HUMAN,tr|A8MXP9|A8MXP9_HUMAN,tr|D6R991|D6R991_HUMAN,tr|D6REK4|D6REK4_HUMAN,tr|A0A0R4J2E8|A0A0R4J2E8_HUMAN,tr|D6RCM3|D6RCM3_HUMAN,tr|D6R8Z5|D6R8Z5_HUMAN,tr|D6REM6|D6REM6_HUMAN" 8 2273.1276 1.37 89662 22578 4 2273.120471 569.2892 Matrin-3 OS=Homo sapiens OX=9606 GN=MATR3 PE=1 SV=2 9.49 3470.5 - 1.62E+06 - - - -3.1173 - 3.249 0.561 - 136.8 1 1 0 -0.0071 22 0 0 0 6.18E+07 4.51E+07 - - - 4.4925 0.9999 221125_WJC_METTL3_EV_vs_WT_F06.22584.22584.4 8.29E-08 19/108 K.K[136.11]AQDEGLLSDVVPFK[136.11]VPGK[136.11].D "sp|P55084|ECHB_HUMAN,tr|F5GZQ3|F5GZQ3_HUMAN" 2 2050.1525 0.77 89666 22584 4 2050.152795 513.5454 "Trifunctional enzyme subunit beta, mitochondrial OS=Homo sapiens OX=9606 GN=HADHB PE=1 SV=3" 6.12 3471.2 - 968040 - - - 0.1478 - 2.476 0.563 - 307.2 1 2 1 0.0003 19 0 0 0 1.30E+07 1.68E+07 - - - 4.433 1 221125_WJC_METTL3_EV_vs_WT_F06.22591.22591.3 3.64E-14 27/84 R.SQDHFHVFVGDLSPEITTEDIK[136.11].A "sp|P31483|TIA1_HUMAN,tr|F8W8I6|F8W8I6_HUMAN,tr|E5RGV5|E5RGV5_HUMAN" 3 2521.2216 1.94 89671 22591 3 2521.222041 841.4145 Nucleolysin TIA-1 isoform p40 OS=Homo sapiens OX=9606 GN=TIA1 PE=1 SV=3 4.42 3472 - 1.59E+06 - - - 0.1614 - 4.559 0.669 - 1043.8 1 2 0 0.0004 22 0 0 0 4.71E+07 2.42E+07 - - - 9.5954 1 221125_WJC_METTL3_EV_vs_WT_F06.22592.22592.2 6.09E-11 25/42 H.SALSSASTSSHNLQSIFNIGSR[166.11].G "sp|P43243|MATR3_HUMAN,tr|A8MXP9|A8MXP9_HUMAN,tr|D6R991|D6R991_HUMAN,tr|D6REK4|D6REK4_HUMAN,tr|A0A0R4J2E8|A0A0R4J2E8_HUMAN,tr|D6RCM3|D6RCM3_HUMAN,tr|D6R8Z5|D6R8Z5_HUMAN,tr|D6REM6|D6REM6_HUMAN" 8 2273.1276 1.1 89672 22592 2 2273.120584 1137.5711 Matrin-3 OS=Homo sapiens OX=9606 GN=MATR3 PE=1 SV=2 9.49 3472.1 - 628611 - - - -3.0676 - 5.056 0.648 - 1291.8 1 1 0 -0.007 22 0 0 0 1.48E+07 1.34E+07 - - - 7.8092 1 221125_WJC_METTL3_EV_vs_WT_F06.22594.22594.3 6.94E-12 27/84 H.SALSSASTSSHNLQSIFNIGSR[166.11].G "sp|P43243|MATR3_HUMAN,tr|A8MXP9|A8MXP9_HUMAN,tr|D6R991|D6R991_HUMAN,tr|D6REK4|D6REK4_HUMAN,tr|A0A0R4J2E8|A0A0R4J2E8_HUMAN,tr|D6RCM3|D6RCM3_HUMAN,tr|D6R8Z5|D6R8Z5_HUMAN,tr|D6REM6|D6REM6_HUMAN" 8 2273.1276 1.34 89673 22594 3 2273.124649 758.7165 Matrin-3 OS=Homo sapiens OX=9606 GN=MATR3 PE=1 SV=2 9.49 3472.3 - 4.90E+07 - - - -1.2793 - 5.147 0.657 - 1084.9 1 1 0 -0.0029 22 0 0 0 1.17E+09 8.68E+08 - - - 9.7485 1 221125_WJC_METTL3_EV_vs_WT_F06.22596.22596.4 9.99E-06 26/126 R.SQDHFHVFVGDLSPEITTEDIK[136.11].A "sp|P31483|TIA1_HUMAN,tr|F8W8I6|F8W8I6_HUMAN,tr|E5RGV5|E5RGV5_HUMAN" 3 2521.2216 1.93 89674 22596 4 2521.219013 631.3127 Nucleolysin TIA-1 isoform p40 OS=Homo sapiens OX=9606 GN=TIA1 PE=1 SV=3 4.42 3472.5 - 4.83E+06 - - - -1.0396 - 3.943 0.648 - 538.7 1 2 0 -0.0026 22 0 0 0 1.86E+08 9.67E+07 - - - 5.3144 1 221125_WJC_METTL3_EV_vs_WT_F06.22597.22597.3 1.15E-14 27/124 R.FSGFGSGAGGKPLEGLSNGNNITSAPPFASAK.A "sp|Q9UKX7|NUP50_HUMAN,tr|B0QY21|B0QY21_HUMAN" 2 3036.4941 1.25 89675 22597 3 3037.479435 1013.172 Nuclear pore complex protein Nup50 OS=Homo sapiens OX=9606 GN=NUP50 PE=1 SV=2 8.59 3472.7 - 1.45E+06 - - - 324.493 - 3.884 0.688 - 386.3 1 2 0 0.9853 32 0 0 0 7.24E+06 5.80E+06 - - - 9.0592 0.9999 221125_WJC_METTL3_EV_vs_WT_F06.22598.22598.3 1.21E-09 18/80 K.QISNLQQSISDAEQRGENALK.D sp|P04264|K2C1_HUMAN 1 2328.167 999 89676 22598 3 2328.164891 777.0629 "Keratin, type II cytoskeletal 1 OS=Homo sapiens OX=9606 GN=KRT1 PE=1 SV=6" 4.68 3472.7 - 2.42E+07 - - - -0.8913 - 3.371 0.546 - 297.8 1 2 1 -0.0021 21 0 0 0 5.97E+08 0.00E+00 - - - 7.5402 0.9999 221125_WJC_METTL3_EV_vs_WT_F06.22600.22600.4 3.51E-07 21/108 K.KAQDEGLLSDVVPFKVPGK.D "sp|P55084|ECHB_HUMAN,tr|F5GZQ3|F5GZQ3_HUMAN" 2 2026.1099 0.77 89678 22600 4 2026.108856 507.5347 "Trifunctional enzyme subunit beta, mitochondrial OS=Homo sapiens OX=9606 GN=HADHB PE=1 SV=3" 6.12 3473 - 1.27E+06 - - - -0.5113 - 3.289 0.549 - 350.6 1 2 1 -0.001 19 0 0 0 1.30E+07 1.68E+07 - - - 4.407 0.9978 221125_WJC_METTL3_EV_vs_WT_F06.22610.22610.4 7.02E-09 18/114 R.PLFPHVLC[160.03]HNC[160.03]AVEFNFGQK.E "sp|Q00839|HNRPU_HUMAN,tr|A0A1W2PQL0|A0A1W2PQL0_HUMAN,tr|A0A1W2PPL4|A0A1W2PPL4_HUMAN,tr|A0A1W2PQ74|A0A1W2PQ74_HUMAN,tr|Q5RI18|Q5RI18_HUMAN,tr|A0A1W2PP35|A0A1W2PP35_HUMAN,tr|A0A1W2PPS1|A0A1W2PPS1_HUMAN,tr|A0A1W2PRZ7|A0A1W2PRZ7_HUMAN,tr|A0A1W2PPH7|A0A1W2PPH7_HUMAN,tr|A0A1W2PP34|A0A1W2PP34_HUMAN,tr|A0A1X7SBS1|A0A1X7SBS1_HUMAN" 11 2413.146 1.29 89686 22610 4 2413.147585 604.2938 Heterogeneous nuclear ribonucleoprotein U OS=Homo sapiens OX=9606 GN=HNRNPU PE=1 SV=6 7.24 3474.2 - 746274 - - - 0.6664 - 4.204 0.552 - 273.7 1 1 0 0.0016 20 0 0 0 6.68E+07 5.16E+07 - - - 4.5103 1 221125_WJC_METTL3_EV_vs_WT_F06.22614.22614.3 2.00E-11 28/104 R.SNGTNTSAPQDIYAVNGIAFHPVHGTL.A "sp|P78406|RAE1L_HUMAN,tr|E9PQ57|E9PQ57_HUMAN" 2 2780.3518 - 89688 22614 3 2780.349578 927.7912 mRNA export factor OS=Homo sapiens OX=9606 GN=RAE1 PE=1 SV=1 5.92 3474.7 - 1.86E+06 - - - -0.8017 - 4.152 0.669 - 650.9 1 1 0 -0.0022 27 0 0 0 - - - - - 9.2732 0.9999 221125_WJC_METTL3_EV_vs_WT_F06.22615.22615.4 1.31E-05 21/156 K.FWEVISDEHGIDPTGSYHGDSDLQLER[166.11].L "sp|Q9BVA1|TBB2B_HUMAN,sp|Q13885|TBB2A_HUMAN" 2 3111.4085 1.12 89689 22615 4 3111.406023 778.8594 Tubulin beta-2B chain OS=Homo sapiens OX=9606 GN=TUBB2B PE=1 SV=1 4.14 3474.8 - 3.97E+06 - - - -0.8099 - 3.464 0.433 - 134.9 1 2 0 -0.0025 27 0 0 0 2.60E+07 2.32E+07 - - - 3.3829 0.9995 221125_WJC_METTL3_EV_vs_WT_F06.22619.22619.4 0.0955 Jun-84 K.ITDWMPDDMNFSDVK.Q sp|P78333|GPC5_HUMAN 1 1812.7699 4.89 89693 22619 4 1812.768637 454.1997 Glypican-5 OS=Homo sapiens OX=9606 GN=GPC5 PE=1 SV=1 3.77 3475.3 - 344482 - - - -0.6813 - 1.112 0.359 - 17.5 1 2 0 -0.0012 15 0 0 0 1.64E+06 3.36E+05 - - - 2.3884 1 221125_WJC_METTL3_EV_vs_WT_F06.22622.22622.3 7.51E-12 26/76 R.HSAEVAGYQDSIGQLENDLR[166.11].N sp|Q16352|AINX_HUMAN 1 2211.0432 3.11 89694 22622 3 2212.034794 738.0217 Alpha-internexin OS=Homo sapiens OX=9606 GN=INA PE=1 SV=2 4.31 3475.7 - 3.73E+06 - - - 448.4919 - 4.301 0.635 - 969.7 1 2 0 0.9916 20 0 0 0 1.99E+08 6.39E+07 - - - 8.8841 1 221125_WJC_METTL3_EV_vs_WT_F06.22626.22626.3 4.79E-10 28/104 R.APFNQEGQSTGPPPLIPGLGQQGAQGR.L sp|Q9C0J8|WDR33_HUMAN 1 2701.3572 2.05 89698 22626 3 2701.353119 901.4597 pre-mRNA 3' end processing protein WDR33 OS=Homo sapiens OX=9606 GN=WDR33 PE=1 SV=2 6.05 3476.2 - 1.40E+06 - - - -1.5203 - 4.234 0.66 - 418.6 1 2 0 -0.0041 27 0 0 0 5.08E+07 2.48E+07 - - - 9.2174 1 221125_WJC_METTL3_EV_vs_WT_F06.22627.22627.3 4.90E-06 15/56 R.QK[136.11]PSNTEDFIEDIVK[136.11].L sp|P46063|RECQ1_HUMAN 1 1777.9069 1.34 89699 22627 3 1777.907696 593.6429 ATP-dependent DNA helicase Q1 OS=Homo sapiens OX=9606 GN=RECQL PE=1 SV=3 4.32 3476.3 - 1.37E+06 - - - 0.4505 - 2.537 0.46 - 340.9 1 2 0 0.0008 15 0 0 0 3.67E+07 2.73E+07 - - - 6.0976 1 221125_WJC_METTL3_EV_vs_WT_F06.22631.22631.4 4.38E-12 23/114 R.PLFPHVLC[160.03]HNC[160.03]AVEFNFGQK[136.11].E "sp|Q00839|HNRPU_HUMAN,tr|A0A1W2PQL0|A0A1W2PQL0_HUMAN,tr|A0A1W2PPL4|A0A1W2PPL4_HUMAN,tr|A0A1W2PQ74|A0A1W2PQ74_HUMAN,tr|Q5RI18|Q5RI18_HUMAN,tr|A0A1W2PP35|A0A1W2PP35_HUMAN,tr|A0A1W2PPS1|A0A1W2PPS1_HUMAN,tr|A0A1W2PRZ7|A0A1W2PRZ7_HUMAN,tr|A0A1W2PPH7|A0A1W2PPH7_HUMAN,tr|A0A1W2PP34|A0A1W2PP34_HUMAN,tr|A0A1X7SBS1|A0A1X7SBS1_HUMAN" 11 2421.1602 1.32 89701 22631 4 2421.155074 606.2973 Heterogeneous nuclear ribonucleoprotein U OS=Homo sapiens OX=9606 GN=HNRNPU PE=1 SV=6 7.24 3476.8 - 1.06E+06 - - - -2.1077 - 4.486 0.624 - 506 1 1 0 -0.0051 20 0 0 0 6.64E+07 5.02E+07 - - - 5.1577 1 221125_WJC_METTL3_EV_vs_WT_F06.22632.22632.3 4.46E-09 28/76 R.HSAEVAGYQDSIGQLENDLR.N sp|Q16352|AINX_HUMAN 1 2201.0349 3.08 89702 22632 3 2201.036342 734.6856 Alpha-internexin OS=Homo sapiens OX=9606 GN=INA PE=1 SV=2 4.31 3476.9 - 1.23E+07 - - - 0.6601 - 4.966 0.702 - 1046.7 1 2 0 0.0015 20 0 0 0 1.97E+08 6.39E+07 - - - 10.2542 1 221125_WJC_METTL3_EV_vs_WT_F06.22634.22634.3 0.00112 17/72 K.ESSHSGVVLSVEEVEAGLK.G "sp|Q9NRA8|4ET_HUMAN,tr|B1AKL4|B1AKL4_HUMAN,tr|B0QYZ7|B0QYZ7_HUMAN" 3 1954.9848 1.6 89704 22634 3 1954.986237 652.6689 Eukaryotic translation initiation factor 4E transporter OS=Homo sapiens OX=9606 GN=EIF4ENIF1 PE=1 SV=2 4.48 3477.1 - 794317 - - - 0.7601 - 3.373 0.446 - 520.4 1 2 0 0.0015 19 0 0 0 6.62E+06 4.14E+06 - - - 6.499 0.9965 221125_WJC_METTL3_EV_vs_WT_F06.22640.22640.4 2.84E-07 17/126 H.SALSSASTSSHNLQSIFNIGSR.G "sp|P43243|MATR3_HUMAN,tr|A8MXP9|A8MXP9_HUMAN,tr|D6R991|D6R991_HUMAN,tr|D6REK4|D6REK4_HUMAN,tr|A0A0R4J2E8|A0A0R4J2E8_HUMAN,tr|D6RCM3|D6RCM3_HUMAN,tr|D6R8Z5|D6R8Z5_HUMAN,tr|D6REM6|D6REM6_HUMAN" 8 2263.1193 1.37 89707 22640 4 2263.118389 566.7871 Matrin-3 OS=Homo sapiens OX=9606 GN=MATR3 PE=1 SV=2 9.49 3477.9 - 1.22E+06 - - - -0.3968 - 2.859 0.515 - 192.6 1 1 0 -0.0009 22 0 0 0 6.18E+07 4.51E+07 - - - 4.052 1 221125_WJC_METTL3_EV_vs_WT_F06.22642.22642.3 6.33E-11 26/104 R.APFNQEGQSTGPPPLIPGLGQQGAQGR[166.11].L sp|Q9C0J8|WDR33_HUMAN 1 2711.3655 2.58 89709 22642 3 2711.367318 904.7958 pre-mRNA 3' end processing protein WDR33 OS=Homo sapiens OX=9606 GN=WDR33 PE=1 SV=2 6.05 3478.1 - 867339 - - - 0.672 - 4.204 0.573 - 373.6 1 2 0 0.0018 27 0 0 0 6.68E+07 2.59E+07 - - - 8.2317 1 221125_WJC_METTL3_EV_vs_WT_F06.22643.22643.4 3.25E-12 31/126 K.KVWYEWAVTAPVC[160.03]SAIHNPTGR.S "sp|O14744|ANM5_HUMAN,tr|H7BZ44|H7BZ44_HUMAN" 2 2541.2587 2.61 89710 22643 4 2541.25924 636.322 Protein arginine N-methyltransferase 5 OS=Homo sapiens OX=9606 GN=PRMT5 PE=1 SV=4 8.21 3478.2 - 763733 - - - 0.2129 - 4.823 0.657 - 815.4 1 2 0 0.0005 22 0 0 0 2.13E+07 8.18E+06 - - - 5.4592 0.9984 221125_WJC_METTL3_EV_vs_WT_F06.22647.22647.3 1.70E-05 15/52 Q.LDGIHLLDPDVVAR[166.11].F sp|Q86U44|MTA70_HUMAN 1 1541.8441 0.02 89714 22647 3 1541.84517 514.9553 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 4.41 3478.7 - 293072 - - - 0.6862 - 3.037 0.535 - 365.4 1 1 0 0.0011 14 0 0 0 5.41E+05 2.62E+07 - - - 7.4566 1 221125_WJC_METTL3_EV_vs_WT_F06.22651.22651.4 1.33E-11 34/198 R.VAWAEADENEEEAVILAQEEEGVEK[136.11]PAETHLSGK[136.11].L "sp|Q96HY6|DDRGK_HUMAN,tr|A0A0A0MRX2|A0A0A0MRX2_HUMAN" 2 3722.777 1.17 89716 22651 4 3722.774525 931.7015 DDRGK domain-containing protein 1 OS=Homo sapiens OX=9606 GN=DDRGK1 PE=1 SV=2 4.03 3479.3 - 1.12E+06 - - - -0.6675 - 5.717 0.705 - 754.9 1 2 0 -0.0025 34 0 0 0 1.68E+07 1.43E+07 - - - 5.8815 1 221125_WJC_METTL3_EV_vs_WT_F06.22652.22652.4 3.07E-17 39/198 R.VAWAEADENEEEAVILAQEEEGVEKPAETHLSGK.L "sp|Q96HY6|DDRGK_HUMAN,tr|A0A0A0MRX2|A0A0A0MRX2_HUMAN" 2 3706.7486 1.16 89717 22652 4 3706.751714 927.6944 DDRGK domain-containing protein 1 OS=Homo sapiens OX=9606 GN=DDRGK1 PE=1 SV=2 4.03 3479.4 - 1.32E+06 - - - 0.8374 - 7.154 0.766 - 1025.9 1 2 0 0.0031 34 0 0 0 1.65E+07 1.43E+07 - - - 6.4792 1 221125_WJC_METTL3_EV_vs_WT_F06.22653.22653.3 1.09E-06 19/96 R.SEIISTAPSSWVVPGPSPNEENNGK.S "sp|Q6W2J9|BCOR_HUMAN,tr|H7BZ37|H7BZ37_HUMAN,tr|H7C2V9|H7C2V9_HUMAN,tr|H7BYY2|H7BYY2_HUMAN,tr|H7C231|H7C231_HUMAN" 5 2595.2453 2.05 89718 22653 3 2595.247871 866.089 BCL-6 corepressor OS=Homo sapiens OX=9606 GN=BCOR PE=1 SV=1 4.25 3479.5 - 1.19E+06 - - - 0.9999 - 3.035 0.525 - 259.2 1 2 0 0.0026 25 0 0 0 8.72E+07 4.25E+07 - - - 6.9467 1 221125_WJC_METTL3_EV_vs_WT_F06.22654.22654.4 3.71E-07 16/108 R.GLLQDDAHPTLVTYADHSK[136.11].L "sp|Q86U44|MTA70_HUMAN,tr|F5H6D8|F5H6D8_HUMAN,tr|H0YFV6|H0YFV6_HUMAN,tr|B4DTN4|B4DTN4_HUMAN" 4 2088.0367 0.02 89719 22654 4 2088.036632 523.0165 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 5.13 3479.6 - 892661 - - - -0.0484 - 2.87 0.526 - 224 1 2 0 -0.0001 19 0 0 0 2.72E+05 1.47E+07 - - - 4.1609 1 221125_WJC_METTL3_EV_vs_WT_F06.22656.22656.3 6.03E-11 21/88 R.NALK[136.11]QETEVELYNEFPEPIK[136.11]LDK[136.11].N "sp|P51149|RAB7A_HUMAN,tr|C9J4V0|C9J4V0_HUMAN,tr|C9J8S3|C9J8S3_HUMAN,tr|C9J4S4|C9J4S4_HUMAN,tr|A0A6Q8PGE6|A0A6Q8PGE6_HUMAN" 5 2770.4491 1.54 89721 22656 3 2770.446559 924.4903 Ras-related protein Rab-7a OS=Homo sapiens OX=9606 GN=RAB7A PE=1 SV=1 4.42 3479.9 - 415225 - - - -0.9273 - 4.238 0.684 - 374.6 1 2 2 -0.0026 23 0 0 0 1.22E+07 7.93E+06 - - - 9.553 1 221125_WJC_METTL3_EV_vs_WT_F06.22659.22659.3 8.24E-08 21/96 R.SEIISTAPSSWVVPGPSPNEENNGK[136.11].S "sp|Q6W2J9|BCOR_HUMAN,tr|H7BZ37|H7BZ37_HUMAN,tr|H7C2V9|H7C2V9_HUMAN,tr|H7BYY2|H7BYY2_HUMAN,tr|H7C231|H7C231_HUMAN" 5 2603.2595 2.05 89722 22659 3 2603.261117 868.7604 BCL-6 corepressor OS=Homo sapiens OX=9606 GN=BCOR PE=1 SV=1 4.25 3480.4 - 957538 - - - 0.6304 - 3.822 0.571 - 372.4 1 2 0 0.0016 25 0 0 0 8.72E+07 4.25E+07 - - - 7.9903 0.9981 221125_WJC_METTL3_EV_vs_WT_F06.22660.22660.3 3.77E-11 20/124 R.FSGFGSGAGGK[136.11]PLEGLSNGNNITSAPPFASAK[136.11].A "sp|Q9UKX7|NUP50_HUMAN,tr|B0QY21|B0QY21_HUMAN" 2 3052.5225 0.79 89723 22660 3 3053.514624 1018.5148 Nuclear pore complex protein Nup50 OS=Homo sapiens OX=9606 GN=NUP50 PE=1 SV=2 8.59 3480.6 - 572770 - - - 325.0132 - 3.058 0.655 - 183.4 1 2 0 0.9921 32 0 0 0 7.24E+06 9.19E+06 - - - 8.1394 0.9975 221125_WJC_METTL3_EV_vs_WT_F06.22661.22661.4 0.00646 15/162 R.AAVAGEDGRMIAGQVLDINLAAEPKVNR.G "sp|P07910|HNRPC_HUMAN,tr|G3V251|G3V251_HUMAN,tr|B4DY08|B4DY08_HUMAN,tr|G3V575|G3V575_HUMAN,tr|B4DSU6|B4DSU6_HUMAN,tr|G3V3K6|G3V3K6_HUMAN,tr|B2R5W2|B2R5W2_HUMAN,tr|G3V4C1|G3V4C1_HUMAN,tr|G3V576|G3V576_HUMAN,tr|G3V5X6|G3V5X6_HUMAN,tr|G3V4W0|G3V4W0_HUMAN,tr|G3V555|G3V555_HUMAN,tr|G3V2Q1|G3V2Q1_HUMAN" 13 2877.5131 2.72 89724 22661 4 2877.509387 720.3855 Heterogeneous nuclear ribonucleoproteins C1\C2 OS=Homo sapiens OX=9606 GN=HNRNPC PE=1 SV=4 4.78 3480.7 - 743681 - - - -1.2817 - 2.358 0.317 - 79.5 1 2 2 -0.0037 28 0 0 0 6.85E+06 2.51E+06 - - - 2.2505 1 221125_WJC_METTL3_EV_vs_WT_F06.22663.22663.4 3.81E-12 25/204 R.YGPQYGHPPPPPPPPEYGPHADSPVLMVYGLDQSK.M "sp|P14866|HNRPL_HUMAN,tr|A0A3B3ITJ4|A0A3B3ITJ4_HUMAN,tr|M0QXS5|M0QXS5_HUMAN" 3 3783.8032 2.24 89726 22663 4 3783.794243 946.9581 Heterogeneous nuclear ribonucleoprotein L OS=Homo sapiens OX=9606 GN=HNRNPL PE=1 SV=2 5.21 3481 - 681596 - - - -2.359 - 4.238 0.648 - 322.5 1 2 0 -0.0089 35 0 0 0 7.02E+06 3.14E+06 - - - 5.2918 1 221125_WJC_METTL3_EV_vs_WT_F06.22666.22666.3 7.05E-13 31/124 K.VGGTNLGAPGAFGQSPFSQPPAPPHQNTFPPR.S sp|Q96I24|FUBP3_HUMAN 1 3227.5901 2.26 89728 22666 3 3227.593658 1076.8706 Far upstream element-binding protein 3 OS=Homo sapiens OX=9606 GN=FUBP3 PE=1 SV=2 9.73 3481.3 - 9.21E+06 - - - 1.1086 - 4.487 0.676 - 576.7 1 2 0 0.0036 32 0 0 0 3.58E+08 1.58E+08 - - - 9.5294 1 221125_WJC_METTL3_EV_vs_WT_F06.22668.22668.4 1.61E-06 30/126 K.K[136.11]VWYEWAVTAPVC[160.03]SAIHNPTGR[166.11].S "sp|O14744|ANM5_HUMAN,tr|H7BZ44|H7BZ44_HUMAN" 2 2559.2812 2.61 89729 22668 4 2559.281514 640.8276 Protein arginine N-methyltransferase 5 OS=Homo sapiens OX=9606 GN=PRMT5 PE=1 SV=4 8.21 3481.5 - 804643 - - - 0.1348 - 4.67 0.605 - 842.8 1 2 0 0.0003 22 0 0 0 2.13E+07 8.18E+06 - - - 4.9961 1 221125_WJC_METTL3_EV_vs_WT_F06.22669.22669.3 2.08E-13 23/84 K.KVWYEWAVTAPVC[160.03]SAIHNPTGR.S "sp|O14744|ANM5_HUMAN,tr|H7BZ44|H7BZ44_HUMAN" 2 2541.2587 10.53 89730 22669 3 2541.268209 848.0935 Protein arginine N-methyltransferase 5 OS=Homo sapiens OX=9606 GN=PRMT5 PE=1 SV=4 8.21 3481.7 - 770581 - - - 3.7422 - 4.319 0.66 - 660.4 1 2 0 0.0095 22 0 0 0 6.62E+06 6.29E+05 - - - 9.3643 0.9999 221125_WJC_METTL3_EV_vs_WT_F06.22670.22670.4 2.59E-08 21/132 R.NALK[136.11]QETEVELYNEFPEPIK[136.11]LDK[136.11].N "sp|P51149|RAB7A_HUMAN,tr|C9J4V0|C9J4V0_HUMAN,tr|C9J8S3|C9J8S3_HUMAN,tr|C9J4S4|C9J4S4_HUMAN,tr|A0A6Q8PGE6|A0A6Q8PGE6_HUMAN" 5 2770.4491 3.34 89731 22670 4 2770.444763 693.6196 Ras-related protein Rab-7a OS=Homo sapiens OX=9606 GN=RAB7A PE=1 SV=1 4.42 3481.7 - 1.88E+06 - - - -1.5756 - 3.583 0.597 - 231.4 1 2 2 -0.0044 23 0 0 0 7.10E+07 2.13E+07 - - - 4.8346 1 221125_WJC_METTL3_EV_vs_WT_F06.22677.22677.4 6.84E-09 27/186 K.VGGTNLGAPGAFGQSPFSQPPAPPHQNTFPPR.S sp|Q96I24|FUBP3_HUMAN 1 3227.5901 2.25 89736 22677 4 3227.594394 807.9048 Far upstream element-binding protein 3 OS=Homo sapiens OX=9606 GN=FUBP3 PE=1 SV=2 9.73 3482.7 - 8.20E+06 - - - 1.3366 - 4.2 0.55 - 211.7 1 2 0 0.0043 32 0 0 0 3.81E+08 1.69E+08 - - - 4.4453 0.9999 221125_WJC_METTL3_EV_vs_WT_F06.22678.22678.4 2.40E-10 24/132 R.NALKQETEVELYNEFPEPIKLDK.N "sp|P51149|RAB7A_HUMAN,tr|C9J4V0|C9J4V0_HUMAN,tr|C9J8S3|C9J8S3_HUMAN,tr|C9J4S4|C9J4S4_HUMAN,tr|A0A6Q8PGE6|A0A6Q8PGE6_HUMAN" 5 2746.4065 3.5 89737 22678 4 2746.411304 687.6089 Ras-related protein Rab-7a OS=Homo sapiens OX=9606 GN=RAB7A PE=1 SV=1 4.42 3482.7 - 3.62E+06 - - - 1.739 - 3.974 0.598 - 306.5 1 2 2 0.0048 23 0 0 0 7.43E+07 2.13E+07 - - - 4.8767 1 221125_WJC_METTL3_EV_vs_WT_F06.22681.22681.4 3.22E-07 18/102 R.K[136.11]NGGLGHMNIALLSDLTK[136.11].Q sp|P30048|PRDX3_HUMAN 1 1897.0426 0.74 89740 22681 4 1897.045582 475.2679 "Thioredoxin-dependent peroxide reductase, mitochondrial OS=Homo sapiens OX=9606 GN=PRDX3 PE=1 SV=3" 8.6 3483.1 - 603798 - - - 1.563 - 2.871 0.537 - 240.4 1 2 0 0.003 18 0 0 0 3.47E+06 4.66E+06 - - - 4.2605 0.9999 221125_WJC_METTL3_EV_vs_WT_F06.22683.22683.4 2.74E-05 17/114 R.TLYVHWTDAGQLTPALLHSR[166.11].C "sp|Q8IY67|RAVR1_HUMAN,tr|E9PAU2|E9PAU2_HUMAN,tr|A0A087WZ13|A0A087WZ13_HUMAN" 3 2288.1941 0.81 89742 22683 4 2288.199376 573.0558 Ribonucleoprotein PTB-binding 1 OS=Homo sapiens OX=9606 GN=RAVER1 PE=1 SV=1 6.61 3483.3 - 410670 - - - 2.2966 - 2.623 0.452 - 158.4 1 2 0 0.0053 20 0 0 0 1.90E+07 2.35E+07 - - - 3.4811 0.9999 221125_WJC_METTL3_EV_vs_WT_F06.22684.22684.3 1.97E-09 17/116 R.SSVELPPYSGTVLC[160.03]GTQAVDK[136.11]LPDGQEYQR[166.11].L "sp|Q14694|UBP10_HUMAN,tr|H3BQC6|H3BQC6_HUMAN" 2 3311.6099 0.98 89743 22684 3 3311.608174 1104.8772 Ubiquitin carboxyl-terminal hydrolase 10 OS=Homo sapiens OX=9606 GN=USP10 PE=1 SV=2 4.32 3483.5 - 398532 - - - -0.5188 - 3.144 0.621 - 117.8 1 2 1 -0.0017 30 0 0 0 5.57E+06 5.70E+06 - - - 8.0984 0.9983 221125_WJC_METTL3_EV_vs_WT_F06.22685.22685.4 2.86E-07 14/96 K.AAIDWFDGK[136.11]EFHGNIIK[136.11].V "sp|Q92804|RBP56_HUMAN,tr|A0A075B7D9|A0A075B7D9_HUMAN" 2 1976.0127 1.04 89744 22685 4 1976.023155 495.0105 TATA-binding protein-associated factor 2N OS=Homo sapiens OX=9606 GN=TAF15 PE=1 SV=1 5.38 3483.6 - 349681 - - - 5.2925 - 2.784 0.525 - 155.5 1 2 1 0.0105 17 0 0 0 3.54E+06 3.40E+06 - - - 4.1482 0.9995 221125_WJC_METTL3_EV_vs_WT_F06.22686.22686.3 0.000159 14/116 R.SSVELPPYSGTVLC[160.03]GTQAVDKLPDGQEYQR.L "sp|Q14694|UBP10_HUMAN,tr|H3BQC6|H3BQC6_HUMAN" 2 3293.5874 0.98 89745 22686 3 3293.593861 1098.8698 Ubiquitin carboxyl-terminal hydrolase 10 OS=Homo sapiens OX=9606 GN=USP10 PE=1 SV=2 4.32 3483.7 - 289760 - - - 1.955 - 2.443 0.458 - 93.4 1 2 1 0.0064 30 0 0 0 5.57E+06 5.70E+06 - - - 5.6995 0.8093 221125_WJC_METTL3_EV_vs_WT_F06.22689.22689.3 1.40E-08 16/112 R.FSSC[160.03]GGGGGSFGAGGGFGSRSLVNLGGSK.S sp|P04264|K2C1_HUMAN 1 2620.2088 71.52 89746 22689 3 2621.192242 874.4102 "Keratin, type II cytoskeletal 1 OS=Homo sapiens OX=9606 GN=KRT1 PE=1 SV=6" 9.51 3484.1 - 5.61E+06 - - - 375.3113 - 2.6 0.595 - 169.9 1 2 1 0.9834 29 0 0 0 1.33E+07 1.86E+05 - - - 7.0995 1 221125_WJC_METTL3_EV_vs_WT_F06.22690.22690.4 3.72E-16 31/126 K.DYYFDSYAHFGIHEEMLKDEVR.T "sp|Q99873|ANM1_HUMAN,sp|Q9NR22|ANM8_HUMAN,tr|E9PQ98|E9PQ98_HUMAN,tr|E9PKG1|E9PKG1_HUMAN,tr|E9PMZ2|E9PMZ2_HUMAN,tr|E9PNR9|E9PNR9_HUMAN,tr|H0YDE4|H0YDE4_HUMAN,tr|E9PMW9|E9PMW9_HUMAN,tr|E9PIX6|E9PIX6_HUMAN" 9 2763.2275 2.17 89747 22690 4 2763.231087 691.8142 Protein arginine N-methyltransferase 1 OS=Homo sapiens OX=9606 GN=PRMT1 PE=1 SV=3 4.57 3484.2 - 2.83E+06 - - - 1.292 - 5.523 0.751 - 456.4 1 2 1 0.0036 22 0 0 0 5.73E+07 2.64E+07 - - - 6.3209 1 221125_WJC_METTL3_EV_vs_WT_F06.22692.22692.4 1.39E-12 22/126 K.DYYFDSYAHFGIHEEMLK[136.11]DEVR[166.11].T "sp|Q99873|ANM1_HUMAN,sp|Q9NR22|ANM8_HUMAN,tr|E9PQ98|E9PQ98_HUMAN,tr|E9PKG1|E9PKG1_HUMAN,tr|E9PMZ2|E9PMZ2_HUMAN,tr|E9PNR9|E9PNR9_HUMAN,tr|H0YDE4|H0YDE4_HUMAN,tr|E9PMW9|E9PMW9_HUMAN,tr|E9PIX6|E9PIX6_HUMAN" 9 2781.25 2.22 89749 22692 4 2781.255717 696.3198 Protein arginine N-methyltransferase 1 OS=Homo sapiens OX=9606 GN=PRMT1 PE=1 SV=3 4.57 3484.4 - 1.52E+06 - - - 2.0602 - 4.57 0.684 - 178.6 1 2 1 0.0057 22 0 0 0 5.40E+07 2.43E+07 - - - 5.6751 0.9999 221125_WJC_METTL3_EV_vs_WT_F06.22693.22693.3 1.78E-09 22/76 K.ALKDENLPPVIC[160.03]QDVENLQK.F "sp|Q9BVL2|NUP58_HUMAN,tr|H7BYF2|H7BYF2_HUMAN,tr|Q5JRG1|Q5JRG1_HUMAN" 3 2322.1889 2.83 89750 22693 3 2322.193684 775.0703 Nucleoporin p58\p45 OS=Homo sapiens OX=9606 GN=NUP58 PE=1 SV=1 4.32 3484.5 - 1.41E+06 - - - 2.0399 - 3.566 0.55 - 501.4 1 2 1 0.0047 20 0 0 0 3.15E+07 1.11E+07 - - - 7.7552 0.9003 221125_WJC_METTL3_EV_vs_WT_F06.22694.22694.3 6.38E-05 15/72 K.R[166.11]R[166.11]AEQDSTTVAAFASSLVS.G "sp|Q86U44|MTA70_HUMAN,tr|F5H6D8|F5H6D8_HUMAN,tr|H0YFV6|H0YFV6_HUMAN,tr|B4DTN4|B4DTN4_HUMAN" 4 2015.0187 0 89751 22694 3 2015.02101 672.6802 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 6.07 3484.6 - 818135 - - - 1.1603 - 2.232 0.367 - 212.1 1 1 1 0.0023 19 0 0 0 3.79E+05 2.70E+08 - - - 4.6036 1 221125_WJC_METTL3_EV_vs_WT_F06.22699.22699.4 1.40E-06 24/114 R.TLYVHWTDAGQLTPALLHSR.C "sp|Q8IY67|RAVR1_HUMAN,tr|E9PAU2|E9PAU2_HUMAN,tr|A0A087WZ13|A0A087WZ13_HUMAN" 3 2278.1859 0.84 89756 22699 4 2278.191588 570.5537 Ribonucleoprotein PTB-binding 1 OS=Homo sapiens OX=9606 GN=RAVER1 PE=1 SV=1 6.61 3485.3 - 517668 - - - 2.5182 - 3.767 0.598 - 319.4 1 2 0 0.0057 20 0 0 0 1.90E+07 2.27E+07 - - - 4.8728 1 221125_WJC_METTL3_EV_vs_WT_F06.22710.22710.4 2.30E-10 15/132 K.IVGAPMHDLLLWNNATVTTC[160.03]HSK.T "sp|P11586|C1TC_HUMAN,tr|F5H2F4|F5H2F4_HUMAN,tr|V9GZ78|V9GZ78_HUMAN,tr|V9GYY3|V9GYY3_HUMAN" 4 2577.2832 0.5 89763 22710 4 2577.29012 645.3281 "C-1-tetrahydrofolate synthase, cytoplasmic OS=Homo sapiens OX=9606 GN=MTHFD1 PE=1 SV=4" 6.91 3486.6 - 526191 - - - 2.6854 - 2.817 0.574 - 114 1 2 0 0.0069 23 0 0 0 4.83E+06 9.67E+06 - - - 4.5557 1 221125_WJC_METTL3_EV_vs_WT_F06.22720.22720.2 9.45E-20 32/62 R.GGGGSFGYSYGGGSGGGFSASSLGGGFGGGSR.G sp|P35527|K1C9_HUMAN 1 2704.1538 999 89771 22720 2 2704.154342 1353.0842 "Keratin, type I cytoskeletal 9 OS=Homo sapiens OX=9606 GN=KRT9 PE=1 SV=3" 8.59 3487.7 - 1.96E+06 - - - 0.1875 - 5.577 0.85 - 2270.5 1 2 0 0.0005 32 0 0 0 1.04E+09 0.00E+00 - - - 9.5443 1 221125_WJC_METTL3_EV_vs_WT_F06.22727.22727.4 3.78E-10 26/156 K.FWEVISDEHGIDPTGTYHGDSDLQLER[166.11].L "sp|P04350|TBB4A_HUMAN,sp|P68371|TBB4B_HUMAN,tr|M0R2D3|M0R2D3_HUMAN,tr|M0QY85|M0QY85_HUMAN,tr|M0QZL7|M0QZL7_HUMAN,tr|M0R0X0|M0R0X0_HUMAN,tr|M0QYM7|M0QYM7_HUMAN,tr|M0R278|M0R278_HUMAN,tr|M0QY37|M0QY37_HUMAN,tr|M0QX14|M0QX14_HUMAN" 10 3125.4242 2.78 89776 22727 4 3125.424453 782.3633 Tubulin beta-4A chain OS=Homo sapiens OX=9606 GN=TUBB4A PE=1 SV=2 4.14 3488.6 - 5.10E+06 - - - 0.0832 - 4.14 0.618 - 380.2 1 2 0 0.0003 27 0 0 0 2.14E+08 7.70E+07 - - - 5.0495 1 221125_WJC_METTL3_EV_vs_WT_F06.22728.22728.3 7.07E-09 19/68 K.YVHYEIDAC[160.03]MDSEAPGSK[136.11].D "sp|Q86U44|MTA70_HUMAN,tr|H0YFV6|H0YFV6_HUMAN" 2 2078.8805 0.001 89777 22728 3 2078.884305 693.9674 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 4.31 3488.7 - 1.37E+06 - - - 1.8342 - 3.092 0.53 - 343.9 1 2 0 0.0038 18 0 0 0 0.00E+00 8.04E+07 - - - 7.2588 0.9832 221125_WJC_METTL3_EV_vs_WT_F06.22731.22731.4 0.000992 16/114 R.K[136.11]IELFGR[166.11]PHNVQPNWITLGN.Q sp|Q86U44|MTA70_HUMAN 1 2350.2665 0.01 89779 22731 4 2350.268111 588.5739 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 8.75 3489 - 606867 - - - 0.6838 - 2.865 0.392 - 175.8 1 1 0 0.0016 20 0 0 0 3.10E+05 2.71E+07 - - - 2.9894 1 221125_WJC_METTL3_EV_vs_WT_F06.22736.22736.4 2.61E-09 24/186 R.GGGGSFGYSYGGGSGGGFSASSLGGGFGGGSR.G sp|P35527|K1C9_HUMAN 1 2704.1538 220.22 89783 22736 4 2704.153618 677.0457 "Keratin, type I cytoskeletal 9 OS=Homo sapiens OX=9606 GN=KRT9 PE=1 SV=3" 8.59 3489.6 - 663312 - - - -0.0802 - 4.231 0.607 - 205.9 1 2 0 -0.0002 32 0 0 0 4.37E+07 1.99E+05 - - - 4.9448 0.9899 221125_WJC_METTL3_EV_vs_WT_F06.22746.22746.3 3.88E-10 25/104 K.DHTPSQELALTQSVGGDSSADR[166.11]LFPPQ.W "sp|Q86U44|MTA70_HUMAN,tr|H0YFV6|H0YFV6_HUMAN" 2 2862.3659 0.001 89788 22746 3 2862.359566 955.1293 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 4.22 3491 - 2.41E+06 - - - -2.2303 - 4.189 0.581 - 246.2 1 1 1 -0.0064 27 0 0 0 0.00E+00 1.06E+08 - - - 8.3114 0.9681 221125_WJC_METTL3_EV_vs_WT_F06.22751.22751.3 3.24E-05 Dec-80 R.FYDQLNHHIFELVSSSDANER[166.11].K sp|P42345|MTOR_HUMAN 1 2530.1752 0.56 89793 22751 3 2531.17108 844.399 Serine\threonine-protein kinase mTOR OS=Homo sapiens OX=9606 GN=MTOR PE=1 SV=1 4.72 3491.5 - 487361 - - - 393.587 - 2.683 0.32 - 122.8 1 2 0 0.9958 21 0 0 0 4.25E+06 7.65E+06 - - - 4.198 1 221125_WJC_METTL3_EV_vs_WT_F06.22755.22755.4 1.66E-08 19/120 R.FYDQLNHHIFELVSSSDANER[166.11].K sp|P42345|MTOR_HUMAN 1 2530.1752 0.85 89795 22755 4 2530.169223 633.5511 Serine\threonine-protein kinase mTOR OS=Homo sapiens OX=9606 GN=MTOR PE=1 SV=1 4.72 3492 - 661538 - - - -2.3765 - 3.507 0.544 - 306 1 2 0 -0.006 21 0 0 0 1.06E+07 1.23E+07 - - - 4.3742 1 221125_WJC_METTL3_EV_vs_WT_F06.22764.22764.3 5.05E-08 15/60 R.HSDELTSLLGYFPNK[136.11]K[136.11].Q "sp|Q92878|RAD50_HUMAN,tr|E7EN38|E7EN38_HUMAN,tr|A0A494BZX5|A0A494BZX5_HUMAN,tr|H7C0P8|H7C0P8_HUMAN,tr|A0A494C1B7|A0A494C1B7_HUMAN,tr|A0A494C122|A0A494C122_HUMAN,tr|A0A494C0Y7|A0A494C0Y7_HUMAN,tr|A0A1W2PQ90|A0A1W2PQ90_HUMAN" 8 1863.9702 0.76 89802 22764 3 1863.971967 622.3307 DNA repair protein RAD50 OS=Homo sapiens OX=9606 GN=RAD50 PE=1 SV=1 6.75 3493.1 - 619194 - - - 0.9673 - 2.607 0.574 - 250.5 1 2 0 0.0018 16 0 0 0 9.26E+06 1.21E+07 - - - 7.3976 1 221125_WJC_METTL3_EV_vs_WT_F06.22771.22771.3 7.03E-13 20/116 K.SLSGK[136.11]PSGSLGIVSNNSVETIGLLQSTSGK[136.11].Q sp|Q9Y2X9|ZN281_HUMAN 1 2932.5688 1.5 89805 22771 3 2932.566569 978.5302 Zinc finger protein 281 OS=Homo sapiens OX=9606 GN=ZNF281 PE=1 SV=1 8.31 3493.9 - 2.35E+06 - - - -0.7591 - 3.623 0.694 - 238.2 1 2 0 -0.0022 30 0 0 0 1.79E+08 1.19E+08 - - - 9.2384 0.9999 221125_WJC_METTL3_EV_vs_WT_F06.22772.22772.4 1.17E-08 21/126 K.YDSDGVWDPEKWHASLYPASGR.S "sp|Q9NRA8|4ET_HUMAN,tr|B1AKL5|B1AKL5_HUMAN,tr|B1AKL4|B1AKL4_HUMAN" 3 2535.1455 0.91 89806 22772 4 2535.145141 634.7937 Eukaryotic translation initiation factor 4E transporter OS=Homo sapiens OX=9606 GN=EIF4ENIF1 PE=1 SV=2 4.66 3494 - 2.25E+06 - - - -0.1424 - 3.881 0.616 - 256.3 1 2 1 -0.0004 22 0 0 0 8.23E+07 9.03E+07 - - - 5.0313 0.9999 221125_WJC_METTL3_EV_vs_WT_F06.22773.22773.4 5.82E-09 18/126 K.YDSDGVWDPEK[136.11]WHASLYPASGR[166.11].S "sp|Q9NRA8|4ET_HUMAN,tr|B1AKL5|B1AKL5_HUMAN,tr|B1AKL4|B1AKL4_HUMAN" 3 2553.168 1.04 89807 22773 4 2553.16441 639.2993 Eukaryotic translation initiation factor 4E transporter OS=Homo sapiens OX=9606 GN=EIF4ENIF1 PE=1 SV=2 4.66 3494.1 - 2.01E+06 - - - -1.3951 - 3.096 0.625 - 197.6 1 2 1 -0.0036 22 0 0 0 8.28E+07 7.97E+07 - - - 5.0348 0.9999 221125_WJC_METTL3_EV_vs_WT_F06.22775.22775.3 2.59E-07 20/64 R.R[166.11]THNGESVSYLFSHVPL.- "sp|P60891|PRPS1_HUMAN,sp|P11908|PRPS2_HUMAN,sp|P21108|PRPS3_HUMAN,tr|A0A6Q8PG31|A0A6Q8PG31_HUMAN,tr|B1ALA9|B1ALA9_HUMAN,tr|H7C540|H7C540_HUMAN,tr|A0A0B4J207|A0A0B4J207_HUMAN" 7 1951.978 0.63 89809 22775 3 1951.970686 651.6666 Ribose-phosphate pyrophosphokinase 1 OS=Homo sapiens OX=9606 GN=PRPS1 PE=1 SV=2 6.92 3494.4 - 633354 - - - -3.7367 - 3.502 0.466 - 520.2 1 2 0 -0.0073 17 0 0 0 9.66E+06 1.54E+07 - - - 6.8997 1 221125_WJC_METTL3_EV_vs_WT_F06.22778.22778.3 5.52E-17 31/116 K.SLSGKPSGSLGIVSNNSVETIGLLQSTSGK.Q sp|Q9Y2X9|ZN281_HUMAN 1 2916.5404 1.5 89810 22778 3 2916.536782 973.1874 Zinc finger protein 281 OS=Homo sapiens OX=9606 GN=ZNF281 PE=1 SV=1 8.31 3494.8 - 4.46E+06 - - - -1.2388 - 5.176 0.749 - 884.7 1 2 0 -0.0036 30 0 0 0 1.79E+08 1.19E+08 - - - 10.6719 1 221125_WJC_METTL3_EV_vs_WT_F06.22781.22781.3 6.02E-09 16/60 R.HSDELTSLLGYFPNKK.Q "sp|Q92878|RAD50_HUMAN,tr|E7EN38|E7EN38_HUMAN,tr|A0A494BZX5|A0A494BZX5_HUMAN,tr|H7C0P8|H7C0P8_HUMAN,tr|A0A494C1B7|A0A494C1B7_HUMAN,tr|A0A494C122|A0A494C122_HUMAN,tr|A0A494C0Y7|A0A494C0Y7_HUMAN,tr|A0A1W2PQ90|A0A1W2PQ90_HUMAN" 8 1847.9418 0.76 89813 22781 3 1847.943171 616.9879 DNA repair protein RAD50 OS=Homo sapiens OX=9606 GN=RAD50 PE=1 SV=1 6.75 3495.1 - 655244 - - - 0.7614 - 2.795 0.547 - 326.7 1 2 0 0.0014 16 0 0 0 9.26E+06 1.21E+07 - - - 7.2754 1 221125_WJC_METTL3_EV_vs_WT_F06.22785.22785.3 1.54E-13 24/84 K.VGRPSNIGQAQPIIDQLAEEAR.A "sp|Q9UHX1|PUF60_HUMAN,tr|A0A0J9YYL3|A0A0J9YYL3_HUMAN,tr|A0A0J9YWM1|A0A0J9YWM1_HUMAN,tr|H0YEM1|H0YEM1_HUMAN,tr|E9PMU7|E9PMU7_HUMAN,tr|E9PN18|E9PN18_HUMAN,tr|A0A0J9YVR6|A0A0J9YVR6_HUMAN,tr|A0A0J9YXX5|A0A0J9YXX5_HUMAN,tr|A0A0J9YXJ8|A0A0J9YXJ8_HUMAN,tr|E9PQ56|E9PQ56_HUMAN,tr|A0A0J9YVP6|A0A0J9YVP6_HUMAN" 11 2361.2401 1.66 89815 22785 3 2361.244512 788.0873 Poly(U)-binding-splicing factor PUF60 OS=Homo sapiens OX=9606 GN=PUF60 PE=1 SV=1 4.68 3495.6 - 742007 - - - 1.8808 - 4.7 0.608 - 728.2 1 2 0 0.0044 22 0 0 0 3.53E+07 2.13E+07 - - - 8.9864 0.9782 221125_WJC_METTL3_EV_vs_WT_F06.22786.22786.3 0.000739 Nov-56 N.QLDGIHLLDPDVVAR[166.11].F sp|Q86U44|MTA70_HUMAN 1 1669.9027 0.08 89816 22786 3 1669.901464 557.6415 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 4.41 3495.8 - 857784 - - - -0.7342 - 2.251 0.346 - 146.1 1 1 0 -0.0012 15 0 0 0 1.59E+06 1.98E+07 - - - 4.5144 0.9999 221125_WJC_METTL3_EV_vs_WT_F06.22787.22787.3 2.50E-10 18/104 K.TSVQFQNFSPTVVHPGDLQTQLAVQTK[136.11].R sp|O95782|AP2A1_HUMAN 1 2977.5389 1.12 89817 22787 3 2977.527485 993.5202 AP-2 complex subunit alpha-1 OS=Homo sapiens OX=9606 GN=AP2A1 PE=1 SV=3 6.41 3495.9 - 617837 - - - -3.829 - 3.365 0.606 - 260.5 1 2 0 -0.0114 27 0 0 0 1.87E+07 1.66E+07 - - - 8.0848 1 221125_WJC_METTL3_EV_vs_WT_F06.22790.22790.3 3.80E-11 22/72 K.VQDTSNTGLGEDIIHQLSK.S sp|Q8IWA0|WDR75_HUMAN 1 2054.028 1.22 89818 22790 3 2054.027716 685.6833 WD repeat-containing protein 75 OS=Homo sapiens OX=9606 GN=WDR75 PE=1 SV=1 4.54 3496.3 - 4.60E+06 - - - -0.1446 - 4.262 0.672 - 711.1 1 2 0 -0.0003 19 0 0 0 2.19E+08 1.80E+08 - - - 9.5938 1 221125_WJC_METTL3_EV_vs_WT_F06.22792.22792.4 3.88E-10 32/156 K.FWEVISDEHGIDPTGTYHGDSDLQLDR.L "sp|P07437|TBB5_HUMAN,tr|Q5JP53|Q5JP53_HUMAN" 2 3101.4003 0.6 89820 22792 4 3101.401421 776.3573 Tubulin beta chain OS=Homo sapiens OX=9606 GN=TUBB PE=1 SV=2 4.08 3496.5 - 6.04E+06 - - - 0.3702 - 4.539 0.639 - 695 1 2 0 0.0011 27 0 0 0 1.77E+08 2.95E+08 - - - 5.2609 0.9999 221125_WJC_METTL3_EV_vs_WT_F06.22795.22795.3 1.06E-08 18/92 K.QSTQVMAASMSAFDPLK[136.11]NQDEINK[136.11].N "sp|Q92734|TFG_HUMAN,tr|A0A6Q8PG00|A0A6Q8PG00_HUMAN,tr|A0A6Q8PH89|A0A6Q8PH89_HUMAN,tr|C9JJP5|C9JJP5_HUMAN,tr|A0A6Q8PG04|A0A6Q8PG04_HUMAN,tr|A0A6Q8PFY7|A0A6Q8PFY7_HUMAN,tr|A0A6Q8PH27|A0A6Q8PH27_HUMAN,tr|A0A6Q8PF40|A0A6Q8PF40_HUMAN,tr|A0A6Q8PGS4|A0A6Q8PGS4_HUMAN,tr|A0A6Q8PFC4|A0A6Q8PFC4_HUMAN" 10 2668.2808 0.77 89821 22795 3 2668.284438 890.4342 Protein TFG OS=Homo sapiens OX=9606 GN=TFG PE=1 SV=2 4.56 3496.9 - 647979 - - - 1.3814 - 3.643 0.617 - 344.7 1 2 1 0.0037 24 0 0 0 1.17E+07 1.52E+07 - - - 8.4206 1 221125_WJC_METTL3_EV_vs_WT_F06.22796.22796.3 5.37E-06 18/64 R.RTHNGESVSYLFSHVPL.- "sp|P60891|PRPS1_HUMAN,sp|P11908|PRPS2_HUMAN,sp|P21108|PRPS3_HUMAN,tr|A0A6Q8PG31|A0A6Q8PG31_HUMAN,tr|B1ALA9|B1ALA9_HUMAN,tr|H7C540|H7C540_HUMAN,tr|A0A0B4J207|A0A0B4J207_HUMAN" 7 1941.9697 0.63 89822 22796 3 1941.973132 648.3305 Ribose-phosphate pyrophosphokinase 1 OS=Homo sapiens OX=9606 GN=PRPS1 PE=1 SV=2 6.92 3497 - 550911 - - - 1.7621 - 3.566 0.529 - 369.5 1 2 0 0.0034 17 0 0 0 9.66E+06 1.54E+07 - - - 7.6489 0.9998 221125_WJC_METTL3_EV_vs_WT_F06.22797.22797.4 0.00101 16/96 R.R[166.11]THNGESVSYLFSHVPL.- "sp|P60891|PRPS1_HUMAN,sp|P11908|PRPS2_HUMAN,sp|P21108|PRPS3_HUMAN,tr|A0A6Q8PG31|A0A6Q8PG31_HUMAN,tr|B1ALA9|B1ALA9_HUMAN,tr|H7C540|H7C540_HUMAN,tr|A0A0B4J207|A0A0B4J207_HUMAN" 7 1951.978 1.01 89823 22797 4 1951.978436 489.0018 Ribose-phosphate pyrophosphokinase 1 OS=Homo sapiens OX=9606 GN=PRPS1 PE=1 SV=2 6.92 3497.1 - 574268 - - - 0.2336 - 2.251 0.367 - 156.4 1 2 0 0.0005 17 0 0 0 1.23E+07 1.22E+07 - - - 2.7019 0.9999 221125_WJC_METTL3_EV_vs_WT_F06.22798.22798.4 0.00997 14/96 R.RTHNGESVSYLFSHVPL.- "sp|P60891|PRPS1_HUMAN,sp|P11908|PRPS2_HUMAN,sp|P21108|PRPS3_HUMAN,tr|A0A6Q8PG31|A0A6Q8PG31_HUMAN,tr|B1ALA9|B1ALA9_HUMAN,tr|H7C540|H7C540_HUMAN,tr|A0A0B4J207|A0A0B4J207_HUMAN" 7 1941.9697 1.01 89824 22798 4 1941.968579 486.4997 Ribose-phosphate pyrophosphokinase 1 OS=Homo sapiens OX=9606 GN=PRPS1 PE=1 SV=2 6.92 3497.2 - 533331 - - - -0.5824 - 2.056 0.446 - 104.7 1 2 0 -0.0011 17 0 0 0 1.23E+07 1.22E+07 - - - 3.3579 1 221125_WJC_METTL3_EV_vs_WT_F06.22801.22801.3 4.00E-07 17/80 R.VIISAPSADAPMFVMGVNHEK[136.11].Y "sp|P04406|G3P_HUMAN,tr|E7EUT5|E7EUT5_HUMAN" 2 2220.1162 1.17 89825 22801 3 2220.117903 741.046 Glyceraldehyde-3-phosphate dehydrogenase OS=Homo sapiens OX=9606 GN=GAPDH PE=1 SV=3 5.32 3497.6 - 1.50E+06 - - - 0.7464 - 3.101 0.56 - 227.1 1 2 0 0.0017 21 0 0 0 3.80E+07 3.24E+07 - - - 7.4962 1 221125_WJC_METTL3_EV_vs_WT_F06.22802.22802.4 5.86E-11 23/174 K.SLSGKPSGSLGIVSNNSVETIGLLQSTSGK.Q sp|Q9Y2X9|ZN281_HUMAN 1 2916.5404 2.13 89826 22802 4 2916.542504 730.1424 Zinc finger protein 281 OS=Homo sapiens OX=9606 GN=ZNF281 PE=1 SV=1 8.31 3497.7 - 1.91E+06 - - - 0.7231 - 4.115 0.591 - 284.5 1 2 0 0.0021 30 0 0 0 2.24E+07 1.05E+07 - - - 4.8024 0.9991 221125_WJC_METTL3_EV_vs_WT_F06.22812.22812.4 3.12E-05 14/120 R.QNGR[166.11]DPPDPYVSLLLLPDK[136.11]NR[166.11].G sp|Q9BSJ8|ESYT1_HUMAN 1 2434.2963 1.29 89834 22812 4 2434.304012 609.5814 Extended synaptotagmin-1 OS=Homo sapiens OX=9606 GN=ESYT1 PE=1 SV=1 6.04 3499.1 - 332785 - - - 3.1689 - 2.477 0.453 - 112.6 1 2 2 0.0077 21 0 0 0 9.48E+06 7.36E+06 - - - 3.4667 1 221125_WJC_METTL3_EV_vs_WT_F06.22814.22814.3 1.25E-14 27/124 R.GGGGSFGYSYGGGSGGGFSASSLGGGFGGGSR.G sp|P35527|K1C9_HUMAN 1 2704.1538 999 89835 22814 3 2704.155533 902.3919 "Keratin, type I cytoskeletal 9 OS=Homo sapiens OX=9606 GN=KRT9 PE=1 SV=3" 8.59 3499.3 - 3.34E+07 - - - 0.6279 - 4.75 0.763 - 370.6 1 2 0 0.0017 32 0 0 0 8.82E+09 0.00E+00 - - - 10.631 1 221125_WJC_METTL3_EV_vs_WT_F06.22816.22816.3 1.03E-12 25/72 K.VQDTSNTGLGEDIIHQLSK[136.11].S sp|Q8IWA0|WDR75_HUMAN 1 2062.0422 1.22 89836 22816 3 2062.043763 688.3547 WD repeat-containing protein 75 OS=Homo sapiens OX=9606 GN=WDR75 PE=1 SV=1 4.54 3499.5 - 1.05E+07 - - - 0.7517 - 4.141 0.657 - 918.4 1 2 0 0.0015 19 0 0 0 2.19E+08 1.80E+08 - - - 9.3554 1 221125_WJC_METTL3_EV_vs_WT_F06.22818.22818.4 3.26E-08 29/162 R.YASIC[160.03]QQNGIVPIVEPEILPDGDHDLKR.C "sp|P04075|ALDOA_HUMAN,sp|P09972|ALDOC_HUMAN,tr|H3BQN4|H3BQN4_HUMAN,tr|H3BPS8|H3BPS8_HUMAN" 4 3175.5972 2.44 89838 22818 4 3175.598061 794.9066 Fructose-bisphosphate aldolase A OS=Homo sapiens OX=9606 GN=ALDOA PE=1 SV=2 4.43 3499.7 - 1.67E+06 - - - 0.2714 - 4.082 0.554 - 409.2 1 2 0 0.0009 28 0 0 0 1.76E+07 7.20E+06 - - - 4.4845 0.821 221125_WJC_METTL3_EV_vs_WT_F06.22821.22821.4 0.405 8/126 R.EAFLNTEDKGDSLDSVEALIKK.H "sp|Q13813|SPTN1_HUMAN,tr|A0A0D9SF54|A0A0D9SF54_HUMAN,tr|A0A0D9SGF6|A0A0D9SGF6_HUMAN" 3 2421.2275 0.27 89841 22821 4 2421.232246 606.3142 "Spectrin alpha chain, non-erythrocytic 1 OS=Homo sapiens OX=9606 GN=SPTAN1 PE=1 SV=3" 4.3 3500 - 383168 - - - 1.9597 - 1.513 0.159 - 35.8 1 2 1 0.0047 22 0 0 0 3.57E+06 1.30E+07 - - - 0.7441 0.9999 221125_WJC_METTL3_EV_vs_WT_F06.22841.22841.2 2.44E-06 30-Nov R.IINEPTAAAIAYGLDK[136.11].R "sp|P11021|BIP_HUMAN,sp|P54652|HSP72_HUMAN,sp|P34931|HS71L_HUMAN,sp|P11142|HSP7C_HUMAN,tr|E9PKE3|E9PKE3_HUMAN,tr|E9PN89|E9PN89_HUMAN,tr|A0A7P0TB36|A0A7P0TB36_HUMAN,tr|E9PLF4|E9PLF4_HUMAN,tr|A0A7P0TAI0|A0A7P0TAI0_HUMAN,tr|Q53FA3|Q53FA3_HUMAN,tr|E9PI65|E9PI65_HUMAN" 11 1666.9021 0.08 89855 22841 2 1666.904361 834.4583 Endoplasmic reticulum chaperone BiP OS=Homo sapiens OX=9606 GN=HSPA5 PE=1 SV=2 4.37 3502.6 - 328516 - - - 1.3342 - 2.757 0.561 - 306.2 1 2 0 0.0022 16 0 0 0 4.38E+05 5.50E+06 - - - 5.6772 0.9999 221125_WJC_METTL3_EV_vs_WT_F06.22847.22847.4 0.00032 12/180 K.VK[136.11]PTLIAVR[166.11]PPVPLPAPSHPASTNEPIVLED.- sp|O94776|MTA2_HUMAN 1 3271.8299 1.19 89858 22847 4 3271.829684 818.9648 Metastasis-associated protein MTA2 OS=Homo sapiens OX=9606 GN=MTA2 PE=1 SV=1 5.54 3503.4 - 538919 - - - -0.0721 - 2.199 0.403 - 43.3 1 2 0 -0.0002 31 0 0 0 1.80E+07 1.52E+07 - - - 2.9731 1 221125_WJC_METTL3_EV_vs_WT_F06.22854.22854.3 8.28E-18 24/104 R.TLTGLINVGSIDC[160.03]QQYHSFC[160.03]AQENVQR[166.11].Y "sp|Q8IXB1|DJC10_HUMAN,tr|A0A7P0Z431|A0A7P0Z431_HUMAN,tr|A0A7P0TB97|A0A7P0TB97_HUMAN,tr|A0A7P0TAQ9|A0A7P0TAQ9_HUMAN" 4 3147.4741 0.9 89863 22854 3 3147.472118 1050.1653 DnaJ homolog subfamily C member 10 OS=Homo sapiens OX=9606 GN=DNAJC10 PE=1 SV=2 5.29 3504.3 - 479563 - - - -0.6418 - 4.47 0.769 - 497.6 1 2 0 -0.002 27 0 0 0 1.27E+07 1.41E+07 - - - 10.558 0.9935 221125_WJC_METTL3_EV_vs_WT_F06.22856.22856.4 0.00025 17/120 R.K[136.11]HAASDVDLEIESLLNQQSTK[136.11].E "sp|Q86U44|MTA70_HUMAN,tr|F5H6D8|F5H6D8_HUMAN,tr|H0YFV6|H0YFV6_HUMAN,tr|B4DTN4|B4DTN4_HUMAN" 4 2341.2096 0.02 89865 22856 4 2342.21355 586.3097 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 4.75 3504.5 - 436628 - - - 428.8087 - 3.141 0.378 - 179.9 1 2 0 1.0039 21 0 0 0 3.29E+06 2.00E+08 - - - 2.6165 1 221125_WJC_METTL3_EV_vs_WT_F06.22861.22861.3 1.02E-20 20/100 K.LKEVDDVLGGAAAWENVDSTAESC[160.03]PK.C sp|Q9Y2Y1|RPC10_HUMAN 1 2760.2912 2.25 89868 22861 3 2760.293088 921.1044 DNA-directed RNA polymerase III subunit RPC10 OS=Homo sapiens OX=9606 GN=POLR3K PE=1 SV=2 4.02 3505.2 - 518088 - - - 0.6695 - 4.149 0.779 - 385.9 1 2 1 0.0018 26 0 0 0 1.05E+07 4.65E+06 - - - 10.4981 1 221125_WJC_METTL3_EV_vs_WT_F06.22862.22862.3 1.45E-08 22/80 K.TRLENQNLLIQVEEVSQTC[160.03]SK.S "sp|Q8IWJ2|GCC2_HUMAN,tr|U3KPU4|U3KPU4_HUMAN,tr|U3KQE0|U3KQE0_HUMAN,tr|B8ZZW2|B8ZZW2_HUMAN" 4 2488.2592 1.33 89869 22862 3 2488.267094 830.427 GRIP and coiled-coil domain-containing protein 2 OS=Homo sapiens OX=9606 GN=GCC2 PE=1 SV=4 4.78 3505.3 - 480922 - - - 3.1918 - 4.444 0.621 - 842 1 2 1 0.0079 21 0 0 0 9.59E+06 7.24E+06 - - - 9.0373 0.9996 221125_WJC_METTL3_EV_vs_WT_F06.22864.22864.4 1.72E-05 14/96 R.WVTYFNKPDIDAWELRK.G "sp|P20674|COX5A_HUMAN,tr|H3BNX8|H3BNX8_HUMAN,tr|H3BRI0|H3BRI0_HUMAN" 3 2180.1055 2.29 89871 22864 4 2180.115451 546.0336 "Cytochrome c oxidase subunit 5A, mitochondrial OS=Homo sapiens OX=9606 GN=COX5A PE=1 SV=2" 6.12 3505.6 - 281786 - - - 4.5759 - 2.313 0.495 - 132.2 1 2 0 0.01 17 0 0 0 5.79E+06 2.53E+06 - - - 3.8229 0.8714 221125_WJC_METTL3_EV_vs_WT_F06.22868.22868.3 1.72E-09 18/72 K.SKELTTEIDNNIEQISSYK.S "sp|P13645|K1C10_HUMAN,tr|A0A1B0GVI3|A0A1B0GVI3_HUMAN" 2 2211.0907 999 89873 22868 3 2212.077702 738.0375 "Keratin, type I cytoskeletal 10 OS=Homo sapiens OX=9606 GN=KRT10 PE=1 SV=6" 4.41 3506.1 - 2.50E+07 - - - 446.3992 - 3.321 0.577 - 353.9 1 2 1 0.987 19 0 0 0 3.24E+06 0.00E+00 - - - 7.6484 1 221125_WJC_METTL3_EV_vs_WT_F06.22878.22878.3 2.41E-10 25/80 R.K[136.11]HAASDVDLEIESLLNQQSTK[136.11].E "sp|Q86U44|MTA70_HUMAN,tr|F5H6D8|F5H6D8_HUMAN,tr|H0YFV6|H0YFV6_HUMAN,tr|B4DTN4|B4DTN4_HUMAN" 4 2341.2096 0 89881 22878 3 2341.21015 781.4105 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 4.75 3507.3 - 809742 - - - 0.2268 - 4.244 0.6 - 983 1 2 0 0.0005 21 0 0 0 9.74E+05 1.95E+08 - - - 8.6948 1 221125_WJC_METTL3_EV_vs_WT_F06.22879.22879.3 6.99E-16 25/104 R.TLTGLINVGSIDC[160.03]QQYHSFC[160.03]AQENVQR.Y "sp|Q8IXB1|DJC10_HUMAN,tr|A0A7P0Z431|A0A7P0Z431_HUMAN,tr|A0A7P0TB97|A0A7P0TB97_HUMAN,tr|A0A7P0TAQ9|A0A7P0TAQ9_HUMAN" 4 3137.4659 0.9 89882 22879 3 3137.46732 1046.8292 DnaJ homolog subfamily C member 10 OS=Homo sapiens OX=9606 GN=DNAJC10 PE=1 SV=2 5.29 3507.5 - 638317 - - - 0.4628 - 4.887 0.797 - 678.7 1 2 0 0.0015 27 0 0 0 1.27E+07 1.41E+07 - - - 11.0755 0.9982 221125_WJC_METTL3_EV_vs_WT_F06.22882.22882.2 0.00476 Jul-36 K.TSSAETPTIPLGSAVEAIK.A "sp|Q16891|MIC60_HUMAN,tr|B9A067|B9A067_HUMAN,tr|C9J406|C9J406_HUMAN,tr|H7C463|H7C463_HUMAN" 4 1870.9888 4.39 89885 22882 2 1870.985424 936.5017 MICOS complex subunit MIC60 OS=Homo sapiens OX=9606 GN=IMMT PE=1 SV=1 4.53 3507.9 - 226779 - - - -1.7905 - 1.483 0.322 - 73.2 1 2 0 -0.0034 19 0 0 0 2.17E+06 4.94E+05 - - - 2.3871 0.9948 221125_WJC_METTL3_EV_vs_WT_F06.22896.22896.4 2.49E-05 12/144 R.FSFLSKPVDENHQQDGDEDSLVSHF.Y "sp|P52948|NUP98_HUMAN,tr|A0A3B3ITD8|A0A3B3ITD8_HUMAN" 2 2876.2889 2.62 89895 22896 4 2876.285334 720.0795 Nuclear pore complex protein Nup98-Nup96 OS=Homo sapiens OX=9606 GN=NUP98 PE=1 SV=4 4.22 3509.6 - 659554 - - - -1.2509 - 2.316 0.488 - 78.3 1 1 0 -0.0036 25 0 0 0 1.48E+07 5.63E+06 - - - 3.7397 1 221125_WJC_METTL3_EV_vs_WT_F06.22901.22901.2 4.33E-07 14/22 K.SLNNQFASFIDK.V sp|P04264|K2C1_HUMAN 1 1382.683 20.13 89898 22901 2 1382.681881 692.3488 "Keratin, type II cytoskeletal 1 OS=Homo sapiens OX=9606 GN=KRT1 PE=1 SV=6" 5.55 3510.2 - 2.85E+06 - - - -0.831 - 2.732 0.556 - 660.4 1 2 0 -0.0011 12 0 0 0 1.05E+08 5.24E+06 - - - 5.7917 1 221125_WJC_METTL3_EV_vs_WT_F06.22902.22902.3 1.80E-06 26/96 K.IDSIPHLNNSTPLVDPSVYGYGVQK.R sp|Q96I24|FUBP3_HUMAN 1 2712.3759 2.16 89899 22902 3 2712.375747 905.1326 Far upstream element-binding protein 3 OS=Homo sapiens OX=9606 GN=FUBP3 PE=1 SV=2 5.21 3510.3 - 2.74E+06 - - - -0.0549 - 4.001 0.635 - 630.7 1 2 0 -0.0001 25 0 0 0 1.26E+08 5.86E+07 - - - 8.8095 1 221125_WJC_METTL3_EV_vs_WT_F06.22904.22904.4 3.15E-06 16/108 R.GLLQDDAHPTLVTYADHSK[136.11].L "sp|Q86U44|MTA70_HUMAN,tr|F5H6D8|F5H6D8_HUMAN,tr|H0YFV6|H0YFV6_HUMAN,tr|B4DTN4|B4DTN4_HUMAN" 4 2088.0367 0.02 89901 22904 4 2088.035881 523.0165 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 5.13 3510.6 - 1.21E+06 - - - -0.408 - 3.304 0.533 - 274.1 1 2 0 -0.0009 19 0 0 0 4.05E+05 1.71E+07 - - - 4.2693 1 221125_WJC_METTL3_EV_vs_WT_F06.22912.22912.3 5.66E-15 28/76 K.K[136.11]MQQNIQELEEQLEEEESAR[166.11].Q sp|P35579|MYH9_HUMAN 1 2478.1663 1.32 89907 22912 3 2478.158031 827.0627 Myosin-9 OS=Homo sapiens OX=9606 GN=MYH9 PE=1 SV=4 4.12 3511.5 - 1.94E+06 - - - -3.3436 - 5.325 0.567 - 1309.4 1 2 0 -0.0083 20 0 0 0 3.28E+07 2.49E+07 - - - 8.9165 1 221125_WJC_METTL3_EV_vs_WT_F06.22931.22931.2 1.72E-11 20/32 L.GNQLDGIHLLDPDVVAR[166.11].F sp|Q86U44|MTA70_HUMAN 1 1840.9671 0.001 89918 22931 2 1841.96986 921.4908 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 4.41 3513.8 - 911068 - - - 544.7023 - 3.432 0.548 - 876.5 1 1 0 1.0028 17 0 0 0 0.00E+00 1.22E+07 - - - 5.8054 1 221125_WJC_METTL3_EV_vs_WT_F06.22933.22933.4 8.99E-09 28/114 K.K[136.11]PVTDC[160.03]VISVPSFFTDAER[166.11]R[166.11].S sp|Q92598|HS105_HUMAN 1 2351.1938 0.001 89920 22933 4 2351.193649 588.8057 Heat shock protein 105 kDa OS=Homo sapiens OX=9606 GN=HSPH1 PE=1 SV=1 6.11 3513.9 - 2.25E+06 - - - -0.0672 - 4.008 0.521 - 462.5 1 2 0 -0.0002 20 0 0 0 0.00E+00 5.85E+07 - - - 4.2249 1 221125_WJC_METTL3_EV_vs_WT_F06.22939.22939.4 3.87E-08 25/96 K.SDFFELLSNHHLDSQSR[166.11].W "sp|O14776|TCRG1_HUMAN,tr|A0A7P0T8N8|A0A7P0T8N8_HUMAN,tr|G3V220|G3V220_HUMAN" 3 2040.9529 0.71 89924 22939 4 2040.951937 511.2455 Transcription elongation regulator 1 OS=Homo sapiens OX=9606 GN=TCERG1 PE=1 SV=2 5.2 3514.6 - 1.97E+06 - - - -0.4655 - 3.992 0.586 - 724.1 1 2 0 -0.0009 17 0 0 0 4.46E+07 6.31E+07 - - - 4.8069 0.9999 221125_WJC_METTL3_EV_vs_WT_F06.22945.22945.4 0.000181 18/132 K.TKPVTGNLRPEEALQALTIYEGK.F "sp|Q14204|DYHC1_HUMAN,tr|A0A7P0T8N2|A0A7P0T8N2_HUMAN,tr|A0A7P0T9C4|A0A7P0T9C4_HUMAN,tr|A0A7P0TBJ7|A0A7P0TBJ7_HUMAN,tr|A0A804HHY6|A0A804HHY6_HUMAN,tr|A0A7P0T9K2|A0A7P0T9K2_HUMAN,tr|A0A7P0TB64|A0A7P0TB64_HUMAN,tr|A0A2R8Y706|A0A2R8Y706_HUMAN,tr|A0A7P0T916|A0A7P0T916_HUMAN,tr|A0A7P0TB75|A0A7P0TB75_HUMAN,tr|A0A7P0T8W5|A0A7P0T8W5_HUMAN,tr|A0A7P0T9S3|A0A7P0T9S3_HUMAN,tr|A0A7P0TAF3|A0A7P0TAF3_HUMAN,tr|A0A7P0T9F1|A0A7P0T9F1_HUMAN,tr|A0A7P0TAW9|A0A7P0TAW9_HUMAN,tr|A0A2R8YGC7|A0A2R8YGC7_HUMAN,tr|A0A7P0TA13|A0A7P0TA13_HUMAN,tr|A0A7P0T934|A0A7P0T934_HUMAN,tr|A0A7P0TAV5|A0A7P0TAV5_HUMAN,tr|A0A7P0T9Y3|A0A7P0T9Y3_HUMAN,tr|A0A7P0T7V5|A0A7P0T7V5_HUMAN,tr|A0A7P0T9R4|A0A7P0T9R4_HUMAN,tr|A0A2R8Y5T0|A0A2R8Y5T0_HUMAN,tr|A0A7P0T990|A0A7P0T990_HUMAN,tr|A0A7P0T942|A0A7P0T942_HUMAN,tr|A0A2R8YFZ7|A0A2R8YFZ7_HUMAN,tr|A0A7P0T825|A0A7P0T825_HUMAN,tr|A0A2R8Y6H2|A0A2R8Y6H2_HUMAN,tr|A0A7P0TAM4|A0A7P0TAM4_HUMAN" 29 2527.3646 0.95 89928 22945 4 2527.365174 632.8484 Cytoplasmic dynein 1 heavy chain 1 OS=Homo sapiens OX=9606 GN=DYNC1H1 PE=1 SV=5 5.9 3515.3 - 1.99E+06 - - - 0.2259 - 3.275 0.404 - 231.8 1 2 0 0.0006 23 0 0 0 7.72E+07 8.09E+07 - - - 3.1266 1 221125_WJC_METTL3_EV_vs_WT_F06.22946.22946.4 2.46E-11 25/144 K.LKEEDMAMNAQQDNILYQTVTGLKK.D sp|Q9BRS2|RIOK1_HUMAN 1 2880.4361 1.69 89929 22946 4 2880.428981 721.1163 Serine\threonine-protein kinase RIO1 OS=Homo sapiens OX=9606 GN=RIOK1 PE=1 SV=2 4.78 3515.4 - 1.46E+06 - - - -2.4819 - 4.594 0.685 - 411.2 1 2 1 -0.0071 25 0 0 0 1.64E+07 9.70E+06 - - - 5.6713 1 221125_WJC_METTL3_EV_vs_WT_F06.22950.22950.4 3.58E-07 18/96 K.SDFFELLSNHHLDSQSR.W "sp|O14776|TCRG1_HUMAN,tr|A0A7P0T8N8|A0A7P0T8N8_HUMAN,tr|G3V220|G3V220_HUMAN" 3 2030.9446 0.71 89931 22950 4 2030.942107 508.7434 Transcription elongation regulator 1 OS=Homo sapiens OX=9606 GN=TCERG1 PE=1 SV=2 5.2 3516 - 2.39E+06 - - - -1.2359 - 3.61 0.609 - 404 1 2 0 -0.0025 17 0 0 0 4.46E+07 6.31E+07 - - - 4.9717 0.9999 221125_WJC_METTL3_EV_vs_WT_F06.22951.22951.4 9.74E-07 24/114 R.R[166.11]K[136.11]DGVFLYFEDNAGVIVNNK[136.11].G "sp|P62829|RL23_HUMAN,tr|J3KT29|J3KT29_HUMAN,tr|J3KTJ3|J3KTJ3_HUMAN" 3 2323.2171 1.02 89932 22951 4 2323.222232 581.8116 60S ribosomal protein L23 OS=Homo sapiens OX=9606 GN=RPL23 PE=1 SV=1 6.12 3516 - 825864 - - - 2.2086 - 3.721 0.57 - 348.1 1 2 1 0.0051 20 0 0 0 1.08E+08 1.06E+08 - - - 4.6252 0.9999 221125_WJC_METTL3_EV_vs_WT_F06.22952.22952.4 6.02E-06 17/132 K.TK[136.11]PVTGNLR[166.11]PEEALQALTIYEGK[136.11].F "sp|Q14204|DYHC1_HUMAN,tr|A0A7P0T8N2|A0A7P0T8N2_HUMAN,tr|A0A7P0T9C4|A0A7P0T9C4_HUMAN,tr|A0A7P0TBJ7|A0A7P0TBJ7_HUMAN,tr|A0A804HHY6|A0A804HHY6_HUMAN,tr|A0A7P0T9K2|A0A7P0T9K2_HUMAN,tr|A0A7P0TB64|A0A7P0TB64_HUMAN,tr|A0A2R8Y706|A0A2R8Y706_HUMAN,tr|A0A7P0T916|A0A7P0T916_HUMAN,tr|A0A7P0TB75|A0A7P0TB75_HUMAN,tr|A0A7P0T8W5|A0A7P0T8W5_HUMAN,tr|A0A7P0T9S3|A0A7P0T9S3_HUMAN,tr|A0A7P0TAF3|A0A7P0TAF3_HUMAN,tr|A0A7P0T9F1|A0A7P0T9F1_HUMAN,tr|A0A7P0TAW9|A0A7P0TAW9_HUMAN,tr|A0A2R8YGC7|A0A2R8YGC7_HUMAN,tr|A0A7P0TA13|A0A7P0TA13_HUMAN,tr|A0A7P0T934|A0A7P0T934_HUMAN,tr|A0A7P0TAV5|A0A7P0TAV5_HUMAN,tr|A0A7P0T9Y3|A0A7P0T9Y3_HUMAN,tr|A0A7P0T7V5|A0A7P0T7V5_HUMAN,tr|A0A7P0T9R4|A0A7P0T9R4_HUMAN,tr|A0A2R8Y5T0|A0A2R8Y5T0_HUMAN,tr|A0A7P0T990|A0A7P0T990_HUMAN,tr|A0A7P0T942|A0A7P0T942_HUMAN,tr|A0A2R8YFZ7|A0A2R8YFZ7_HUMAN,tr|A0A7P0T825|A0A7P0T825_HUMAN,tr|A0A2R8Y6H2|A0A2R8Y6H2_HUMAN,tr|A0A7P0TAM4|A0A7P0TAM4_HUMAN" 29 2553.4013 0.97 89933 22952 4 2553.399652 639.3576 Cytoplasmic dynein 1 heavy chain 1 OS=Homo sapiens OX=9606 GN=DYNC1H1 PE=1 SV=5 5.9 3516.1 - 2.13E+06 - - - -0.6348 - 2.998 0.462 - 206.8 1 2 0 -0.0016 23 0 0 0 7.90E+07 8.11E+07 - - - 3.6025 1 221125_WJC_METTL3_EV_vs_WT_F06.22954.22954.3 1.12E-11 23/104 K.SGTQDIQPGPLFNNNADGVATDITSTR.S "sp|Q7Z2W4|ZCCHV_HUMAN,tr|C9J6P4|C9J6P4_HUMAN,tr|A0A7P0T8C6|A0A7P0T8C6_HUMAN" 3 2788.3264 0.87 89935 22954 3 2788.318549 930.4494 Zinc finger CCCH-type antiviral protein 1 OS=Homo sapiens OX=9606 GN=ZC3HAV1 PE=1 SV=3 3.93 3516.3 - 1.11E+06 - - - -2.8085 - 3.913 0.66 - 451.4 1 2 0 -0.0078 27 0 0 0 1.67E+08 1.93E+08 - - - 9.0349 1 221125_WJC_METTL3_EV_vs_WT_F06.22961.22961.4 1.46E-14 31/150 K.EVLAGRPLFPHVLC[160.03]HNC[160.03]AVEFNFGQK.E "sp|Q00839|HNRPU_HUMAN,tr|A0A1W2PQL0|A0A1W2PQL0_HUMAN,tr|A0A1W2PPL4|A0A1W2PPL4_HUMAN,tr|A0A1W2PQ74|A0A1W2PQ74_HUMAN,tr|Q5RI18|Q5RI18_HUMAN,tr|A0A1W2PP35|A0A1W2PP35_HUMAN,tr|A0A1W2PPS1|A0A1W2PPS1_HUMAN,tr|A0A1W2PRZ7|A0A1W2PRZ7_HUMAN,tr|A0A1W2PPH7|A0A1W2PPH7_HUMAN,tr|A0A1W2PP34|A0A1W2PP34_HUMAN,tr|A0A1X7SBS1|A0A1X7SBS1_HUMAN" 11 3038.5007 1.06 89940 22961 4 3038.503483 760.6325 Heterogeneous nuclear ribonucleoprotein U OS=Homo sapiens OX=9606 GN=HNRNPU PE=1 SV=6 6.99 3517.2 - 3.43E+06 - - - 0.9037 - 4.859 0.676 - 793.6 1 2 0 0.0027 26 0 0 0 2.01E+08 1.90E+08 - - - 5.6078 1 221125_WJC_METTL3_EV_vs_WT_F06.22963.22963.3 1.82E-07 24/64 K.SDFFELLSNHHLDSQSR[166.11].W "sp|O14776|TCRG1_HUMAN,tr|A0A7P0T8N8|A0A7P0T8N8_HUMAN,tr|G3V220|G3V220_HUMAN" 3 2040.9529 0.71 89942 22963 3 2040.951308 681.3249 Transcription elongation regulator 1 OS=Homo sapiens OX=9606 GN=TCERG1 PE=1 SV=2 5.2 3517.4 - 2.36E+06 - - - -0.7737 - 4.021 0.609 - 941.8 1 2 0 -0.0016 17 0 0 0 2.12E+07 2.99E+07 - - - 8.8447 1 221125_WJC_METTL3_EV_vs_WT_F06.22968.22968.3 3.01E-14 27/112 K.YSSQFGGGSQYAYFHEEDESSFQLVDTAR[166.11].T "sp|O15371|EIF3D_HUMAN,tr|B0QYA8|B0QYA8_HUMAN,tr|B0QYA6|B0QYA6_HUMAN,tr|B0QYA5|B0QYA5_HUMAN" 4 3314.4304 1.31 89945 22968 3 3314.423619 1105.8174 Eukaryotic translation initiation factor 3 subunit D OS=Homo sapiens OX=9606 GN=EIF3D PE=1 SV=1 4.17 3518.1 - 1.02E+06 - - - -2.0462 - 5.212 0.741 - 793.7 1 2 0 -0.0068 29 0 0 0 1.41E+07 1.08E+07 - - - 10.5978 1 221125_WJC_METTL3_EV_vs_WT_F06.22971.22971.3 8.62E-15 24/104 K.SGTQDIQPGPLFNNNADGVATDITSTR[166.11].S "sp|Q7Z2W4|ZCCHV_HUMAN,tr|C9J6P4|C9J6P4_HUMAN,tr|A0A7P0T8C6|A0A7P0T8C6_HUMAN" 3 2798.3346 0.87 89948 22971 3 2798.333062 933.7855 Zinc finger CCCH-type antiviral protein 1 OS=Homo sapiens OX=9606 GN=ZC3HAV1 PE=1 SV=3 3.93 3518.4 - 1.62E+06 - - - -0.5675 - 4.279 0.691 - 508.8 1 2 0 -0.0016 27 0 0 0 1.68E+08 1.93E+08 - - - 9.588 1 221125_WJC_METTL3_EV_vs_WT_F06.22975.22975.3 5.33E-18 24/112 K.YSSQFGGGSQYAYFHEEDESSFQLVDTAR.T "sp|O15371|EIF3D_HUMAN,tr|B0QYA8|B0QYA8_HUMAN,tr|B0QYA6|B0QYA6_HUMAN,tr|B0QYA5|B0QYA5_HUMAN" 4 3304.4221 1.31 89952 22975 3 3304.426067 1102.4813 Eukaryotic translation initiation factor 3 subunit D OS=Homo sapiens OX=9606 GN=EIF3D PE=1 SV=1 4.17 3518.9 - 826523 - - - 1.1911 - 4.854 0.788 - 574 1 2 0 0.0039 29 0 0 0 1.40E+07 1.07E+07 - - - 10.9589 0.9991 221125_WJC_METTL3_EV_vs_WT_F06.22976.22976.2 0.00208 16-Sep K.LLQDFFNGR[166.11].D "sp|P0DMV8|HS71A_HUMAN,sp|P0DMV9|HS71B_HUMAN,tr|V9GZ37|V9GZ37_HUMAN,tr|A0A0G2JIW1|A0A0G2JIW1_HUMAN" 4 1118.5748 10.61 89953 22976 2 1118.578211 560.2947 Heat shock 70 kDa protein 1A OS=Homo sapiens OX=9606 GN=HSPA1A PE=1 SV=1 5.84 3519.1 - 812626 - - - 3.0378 - 1.968 0.425 - 190.5 1 2 0 0.0034 9 0 0 0 2.43E+08 2.29E+07 - - - 4.1376 0.9999 221125_WJC_METTL3_EV_vs_WT_F06.22979.22979.3 7.76E-07 22/72 R.IQEIIEQLDVTTSEYEK[136.11]EK[136.11].L "sp|P10809|CH60_HUMAN,tr|A0A7I2V2X6|A0A7I2V2X6_HUMAN,tr|A0A7I2YQK6|A0A7I2YQK6_HUMAN,tr|A0A7I2V599|A0A7I2V599_HUMAN" 4 2310.1813 1.57 89954 22979 3 2310.184373 771.0677 "60 kDa heat shock protein, mitochondrial OS=Homo sapiens OX=9606 GN=HSPD1 PE=1 SV=2" 4.14 3519.4 - 3.52E+06 - - - 1.3133 - 4.207 0.452 - 620 1 2 1 0.003 19 0 0 0 3.76E+08 2.39E+08 - - - 7.1083 1 221125_WJC_METTL3_EV_vs_WT_F06.22982.22982.3 1.48E-09 19/64 K.SDFFELLSNHHLDSQSR.W "sp|O14776|TCRG1_HUMAN,tr|A0A7P0T8N8|A0A7P0T8N8_HUMAN,tr|G3V220|G3V220_HUMAN" 3 2030.9446 0.71 89957 22982 3 2030.951295 677.9888 Transcription elongation regulator 1 OS=Homo sapiens OX=9606 GN=TCERG1 PE=1 SV=2 5.2 3519.8 - 1.70E+06 - - - 3.2881 - 4.146 0.632 - 646.9 1 2 0 0.0067 17 0 0 0 2.12E+07 2.99E+07 - - - 9.1771 0.9999 221125_WJC_METTL3_EV_vs_WT_F06.22987.22987.4 2.13E-13 21/126 R.K[136.11]LFIGGLSFETTDDSLR[166.11]EHFEK[136.11].W "sp|P51991|ROA3_HUMAN,tr|A0A7I2V5D8|A0A7I2V5D8_HUMAN,tr|A0A7I2V2R3|A0A7I2V2R3_HUMAN,tr|A0A7I2V4J6|A0A7I2V4J6_HUMAN,tr|A0A7I2V4G0|A0A7I2V4G0_HUMAN,tr|A0A7I2V402|A0A7I2V402_HUMAN" 6 2594.3227 1.7 89960 22987 4 2594.321696 649.5879 Heterogeneous nuclear ribonucleoprotein A3 OS=Homo sapiens OX=9606 GN=HNRNPA3 PE=1 SV=2 4.9 3520.6 - 2.55E+06 - - - -0.3828 - 4.113 0.574 - 319.8 1 2 1 -0.001 22 0 0 0 1.02E+08 5.96E+07 - - - 4.6845 0.9994 221125_WJC_METTL3_EV_vs_WT_F06.22994.22994.3 6.90E-06 13/88 R.EQPEK[136.11]EPELQQYVPQLQNNTILR[166.11].L sp|Q14152|EIF3A_HUMAN 1 2811.4522 1.33 89965 22994 3 2811.458619 938.158 Eukaryotic translation initiation factor 3 subunit A OS=Homo sapiens OX=9606 GN=EIF3A PE=1 SV=1 4.49 3521.4 - 374124 - - - 2.2857 - 2.478 0.464 - 85.3 1 2 1 0.0064 23 0 0 0 8.14E+06 6.12E+06 - - - 5.8402 1 221125_WJC_METTL3_EV_vs_WT_F06.22997.22997.3 1.49E-12 23/104 K.DHTPSQELALTQSVGGDSSADR[166.11]LFPPQ.W "sp|Q86U44|MTA70_HUMAN,tr|H0YFV6|H0YFV6_HUMAN" 2 2862.3659 0.01 89967 22997 3 2862.36385 955.1293 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 4.22 3521.7 - 1.64E+06 - - - -0.7337 - 4.451 0.631 - 203.5 1 1 1 -0.0021 27 0 0 0 1.07E+06 9.65E+07 - - - 9.0096 0.9988 221125_WJC_METTL3_EV_vs_WT_F06.22998.22998.4 0.853 13/114 R.GFAFVTFDDHDTVDKIVVQK.Y "sp|P51991|ROA3_HUMAN,tr|A0A7I2V5D8|A0A7I2V5D8_HUMAN,tr|A0A7I2V2R3|A0A7I2V2R3_HUMAN,tr|A0A7I2V4J6|A0A7I2V4J6_HUMAN,tr|A0A7I2V4G0|A0A7I2V4G0_HUMAN" 5 2280.1426 0.25 89968 22998 4 2280.140606 571.0429 Heterogeneous nuclear ribonucleoprotein A3 OS=Homo sapiens OX=9606 GN=HNRNPA3 PE=1 SV=2 4.56 3521.8 - 1.14E+06 - - - -0.896 - 2.586 0.352 - 62.3 1 2 1 -0.002 20 0 0 0 1.05E+07 4.19E+07 - - - 2.6069 0.9929 221125_WJC_METTL3_EV_vs_WT_F06.23000.23000.4 0.0317 21/198 R.VVPGFIVQGGDPTGTGSGGESIYGAPFK[136.11]DEFHSR[166.11].L "sp|Q6UX04|CWC27_HUMAN,tr|D6REK3|D6REK3_HUMAN" 2 3482.6862 0.51 89970 23000 4 3482.690594 871.6788 Spliceosome-associated protein CWC27 homolog OS=Homo sapiens OX=9606 GN=CWC27 PE=1 SV=1 4.75 3522.1 - 981808 - - - 1.2706 - 1.812 0.278 - 59.2 1 2 1 0.0044 34 0 0 0 1.18E+07 2.29E+07 - - - 1.8218 0.9999 221125_WJC_METTL3_EV_vs_WT_F06.23005.23005.4 3.09E-12 22/114 R.RKDGVFLYFEDNAGVIVNNK.G "sp|P62829|RL23_HUMAN,tr|J3KT29|J3KT29_HUMAN,tr|J3KTJ3|J3KTJ3_HUMAN" 3 2297.1804 1.07 89973 23005 4 2297.183034 575.3024 60S ribosomal protein L23 OS=Homo sapiens OX=9606 GN=RPL23 PE=1 SV=1 6.12 3522.7 - 6.91E+06 - - - 1.1331 - 3.758 0.489 - 320.1 1 2 1 0.0026 20 0 0 0 1.07E+08 1.01E+08 - - - 3.9241 0.9999 221125_WJC_METTL3_EV_vs_WT_F06.23007.23007.4 0.00112 17/144 K.QVQEYQDLLTPVLHHTTEGYPVVPK.Y sp|Q93100|KPBB_HUMAN 1 2890.4865 0.86 89975 23007 4 2890.491379 723.6289 Phosphorylase b kinase regulatory subunit beta OS=Homo sapiens OX=9606 GN=PHKB PE=1 SV=3 5.27 3523 - 840782 - - - 1.6848 - 3.199 0.459 - 96.3 1 2 0 0.0049 25 0 0 0 1.43E+07 1.66E+07 - - - 3.5897 1 221125_WJC_METTL3_EV_vs_WT_F06.23014.23014.3 1.43E-11 22/72 R.IQEIIEQLDVTTSEYEKEK.L "sp|P10809|CH60_HUMAN,tr|A0A7I2V2X6|A0A7I2V2X6_HUMAN,tr|A0A7I2YQK6|A0A7I2YQK6_HUMAN,tr|A0A7I2V599|A0A7I2V599_HUMAN" 4 2294.1529 1.57 89980 23014 3 2294.15408 765.7249 "60 kDa heat shock protein, mitochondrial OS=Homo sapiens OX=9606 GN=HSPD1 PE=1 SV=2" 4.14 3523.8 - 1.89E+07 - - - 0.4974 - 4.289 0.614 - 621.4 1 2 1 0.0011 19 0 0 0 3.80E+08 2.42E+08 - - - 8.9624 1 221125_WJC_METTL3_EV_vs_WT_F06.23016.23016.3 9.47E-12 31/76 R.R[166.11]K[136.11]DGVFLYFEDNAGVIVNNK[136.11].G "sp|P62829|RL23_HUMAN,tr|J3KT29|J3KT29_HUMAN,tr|J3KTJ3|J3KTJ3_HUMAN" 3 2323.2171 2.41 89982 23016 3 2323.217387 775.413 60S ribosomal protein L23 OS=Homo sapiens OX=9606 GN=RPL23 PE=1 SV=1 6.12 3524 - 2.50E+06 - - - 0.1231 - 4.862 0.674 - 1700 1 2 1 0.0003 20 0 0 0 1.44E+08 6.00E+07 - - - 9.891 1 221125_WJC_METTL3_EV_vs_WT_F06.23022.23022.4 1.54E-11 20/138 K.TVEEVLGHFGVNESTGLSLEQVK[136.11]K[136.11].L "sp|P16615|AT2A2_HUMAN,tr|J3QSY6|J3QSY6_HUMAN" 2 2615.3777 1.38 89986 23022 4 2615.378601 654.8517 Sarcoplasmic\endoplasmic reticulum calcium ATPase 2 OS=Homo sapiens OX=9606 GN=ATP2A2 PE=1 SV=1 4.9 3524.7 - 2.18E+06 - - - 0.3265 - 3.505 0.678 - 235.7 1 2 0 0.0009 24 0 0 0 6.92E+07 5.00E+07 - - - 5.5296 1 221125_WJC_METTL3_EV_vs_WT_F06.23023.23023.4 5.12E-11 19/186 K.WSGPLSLQEVDEQPQHPLHVTYAGAAVDELGK.V sp|P30086|PEBP1_HUMAN 1 3470.7106 1.58 89987 23023 4 3470.711685 868.6849 Phosphatidylethanolamine-binding protein 1 OS=Homo sapiens OX=9606 GN=PEBP1 PE=1 SV=3 4.49 3524.9 - 1.17E+06 - - - 0.2985 - 4.745 0.552 - 187.3 1 2 0 0.001 32 0 0 0 1.89E+07 1.20E+07 - - - 4.5005 1 221125_WJC_METTL3_EV_vs_WT_F06.23029.23029.4 2.69E-14 27/156 K.K[136.11]LGNNC[160.03]VFAPADVTSEK[136.11]DVQTALALAK[136.11].G "sp|Q99714|HCD2_HUMAN,tr|Q5H928|Q5H928_HUMAN,tr|A0A804HHW5|A0A804HHW5_HUMAN" 3 2883.5226 0.72 89991 23029 4 2883.522727 721.8879 3-hydroxyacyl-CoA dehydrogenase type-2 OS=Homo sapiens OX=9606 GN=HSD17B10 PE=1 SV=3 6.11 3525.7 - 1.32E+06 - - - 0.0288 - 5.099 0.671 - 547.4 1 2 1 0.0001 27 0 0 0 1.66E+07 2.29E+07 - - - 5.5761 1 221125_WJC_METTL3_EV_vs_WT_F06.23031.23031.4 4.16E-07 16/132 R.DGAAYFYGPIFIHPEETEHEPTK.M "sp|Q86U86|PB1_HUMAN,tr|E7EVG2|E7EVG2_HUMAN" 2 2647.2231 4.11 89993 23031 4 2647.223891 662.813 Protein polybromo-1 OS=Homo sapiens OX=9606 GN=PBRM1 PE=1 SV=1 4.56 3525.9 - 1.88E+06 - - - 0.3048 - 3.437 0.519 - 123.7 1 2 0 0.0008 23 0 0 0 1.20E+08 2.93E+07 - - - 4.1431 1 221125_WJC_METTL3_EV_vs_WT_F06.23032.23032.4 5.05E-12 25/132 R.DGAAYFYGPIFIHPEETEHEPTK[136.11].M "sp|Q86U86|PB1_HUMAN,tr|E7EVG2|E7EVG2_HUMAN" 2 2655.2373 4.09 89994 23032 4 2655.239605 664.8166 Protein polybromo-1 OS=Homo sapiens OX=9606 GN=PBRM1 PE=1 SV=1 4.56 3526 - 894038 - - - 0.8741 - 3.598 0.683 - 399.7 1 2 0 0.0023 23 0 0 0 1.20E+08 2.93E+07 - - - 5.585 1 221125_WJC_METTL3_EV_vs_WT_F06.23043.23043.3 7.72E-09 16/68 K.YVHYEIDAC[160.03]MDSEAPGSK[136.11].D "sp|Q86U44|MTA70_HUMAN,tr|H0YFV6|H0YFV6_HUMAN" 2 2078.8805 0.04 90001 23043 3 2078.876501 693.9674 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 4.31 3527.4 - 1.12E+06 - - - -1.9198 - 3.32 0.645 - 280.4 1 2 0 -0.004 18 0 0 0 1.28E+06 3.55E+07 - - - 8.718 0.9987 221125_WJC_METTL3_EV_vs_WT_F06.23044.23044.4 1.74E-06 24/156 K.KLGNNC[160.03]VFAPADVTSEKDVQTALALAK.G "sp|Q99714|HCD2_HUMAN,tr|Q5H928|Q5H928_HUMAN,tr|A0A804HHW5|A0A804HHW5_HUMAN" 3 2859.48 0.72 90002 23044 4 2859.495664 715.8773 3-hydroxyacyl-CoA dehydrogenase type-2 OS=Homo sapiens OX=9606 GN=HSD17B10 PE=1 SV=3 6.11 3527.5 - 977432 - - - 5.4625 - 4.38 0.563 - 308.1 1 2 1 0.0156 27 0 0 0 1.66E+07 2.29E+07 - - - 4.5842 0.9996 221125_WJC_METTL3_EV_vs_WT_F06.23045.23045.4 1.32E-09 22/156 K.HTGPGILSMANAGPNTNGSQFFIC[160.03]TAK[136.11].T "sp|P62937|PPIA_HUMAN,tr|C9J5S7|C9J5S7_HUMAN,tr|A0A7I2V4V1|A0A7I2V4V1_HUMAN,tr|F8WE65|F8WE65_HUMAN" 4 2798.336 0.71 90003 23045 4 2799.341643 700.5913 Peptidyl-prolyl cis-trans isomerase A OS=Homo sapiens OX=9606 GN=PPIA PE=1 SV=2 8.23 3527.6 - 755792 - - - 359.3829 - 3.905 0.623 - 252.5 1 2 0 1.0057 27 0 0 0 9.50E+06 1.33E+07 - - - 4.7963 0.9997 221125_WJC_METTL3_EV_vs_WT_F06.23046.23046.4 0.000548 16/120 K.DNHSPEIQHGSLLALGFTVGR[166.11].Y "sp|Q5VYK3|ECM29_HUMAN,tr|J3KN16|J3KN16_HUMAN,tr|A0A804HJA4|A0A804HJA4_HUMAN,tr|R4GMY1|R4GMY1_HUMAN" 4 2257.1479 0.67 90004 23046 4 2257.145946 565.2943 Proteasome adapter and scaffold protein ECM29 OS=Homo sapiens OX=9606 GN=ECPAS PE=1 SV=2 5.99 3527.8 - 467444 - - - -0.8653 - 2.847 0.356 - 199.4 1 2 0 -0.002 21 0 0 0 5.10E+06 7.62E+06 - - - 2.67 1 221125_WJC_METTL3_EV_vs_WT_F06.23051.23051.4 2.13E-10 19/180 K.ANFSLPEK[136.11]C[160.03]DYMDEVTYGELEK[136.11]EEAQPIVTK[136.11].Y "sp|Q1KMD3|HNRL2_HUMAN,tr|H3BQZ7|H3BQZ7_HUMAN" 2 3656.7328 1.96 90007 23051 4 3656.733435 915.1905 Heterogeneous nuclear ribonucleoprotein U-like protein 2 OS=Homo sapiens OX=9606 GN=HNRNPUL2 PE=1 SV=1 4.17 3528.4 - 1.03E+06 - - - 0.1646 - 3.584 0.669 - 171 1 2 2 0.0006 31 0 0 0 2.30E+07 1.17E+07 - - - 5.4368 0.9997 221125_WJC_METTL3_EV_vs_WT_F06.23052.23052.4 0.000701 19/150 R.SFGTEDRPTDRPAPPREEIYEYIIFR.G "sp|Q9BX40|LS14B_HUMAN,tr|Q5TBQ1|Q5TBQ1_HUMAN,tr|A0A0C4DFV2|A0A0C4DFV2_HUMAN,tr|Q5TBQ0|Q5TBQ0_HUMAN" 4 3153.552 0.81 90008 23052 4 3153.559444 789.3953 Protein LSM14 homolog B OS=Homo sapiens OX=9606 GN=LSM14B PE=1 SV=1 4.66 3528.5 - 984637 - - - 2.3722 - 2.864 0.491 - 44.9 1 2 1 0.0075 26 0 0 0 1.34E+07 1.65E+07 - - - 3.8295 1 221125_WJC_METTL3_EV_vs_WT_F06.23053.23053.4 6.30E-12 19/156 K.HTGPGILSMANAGPNTNGSQFFIC[160.03]TAK.T "sp|P62937|PPIA_HUMAN,tr|C9J5S7|C9J5S7_HUMAN,tr|A0A7I2V4V1|A0A7I2V4V1_HUMAN,tr|F8WE65|F8WE65_HUMAN" 4 2790.3218 0.69 90009 23053 4 2790.324604 698.5877 Peptidyl-prolyl cis-trans isomerase A OS=Homo sapiens OX=9606 GN=PPIA PE=1 SV=2 8.23 3528.7 - 704904 - - - 1.016 - 4.711 0.647 - 227.2 1 2 0 0.0028 27 0 0 0 9.31E+06 1.35E+07 - - - 5.3417 0.9999 221125_WJC_METTL3_EV_vs_WT_F06.23055.23055.4 7.54E-05 16/102 R.EQIKSLNNQFASFIDKVR.F sp|P04264|K2C1_HUMAN 1 2136.1328 57.01 90011 23055 4 2136.134182 535.0405 "Keratin, type II cytoskeletal 1 OS=Homo sapiens OX=9606 GN=KRT1 PE=1 SV=6" 8.69 3528.9 - 582347 - - - 0.669 - 2.714 0.497 - 241.5 1 2 2 0.0014 18 0 0 0 1.01E+07 1.77E+05 - - - 3.8935 1 221125_WJC_METTL3_EV_vs_WT_F06.23059.23059.3 5.09E-14 25/124 R.GGGGSFGYSYGGGSGGGFSASSLGGGFGGGSR.G sp|P35527|K1C9_HUMAN 1 2704.1538 999 90013 23059 3 2704.156116 902.3919 "Keratin, type I cytoskeletal 9 OS=Homo sapiens OX=9606 GN=KRT9 PE=1 SV=3" 8.59 3529.4 - 3.10E+06 - - - 0.8435 - 4.459 0.717 - 316.2 1 2 0 0.0023 32 0 0 0 4.09E+07 0.00E+00 - - - 9.9725 0.9997 221125_WJC_METTL3_EV_vs_WT_F06.23061.23061.3 6.35E-05 13/44 K.IEEIK[136.11]DFLLTAR[166.11].R "sp|P63173|RL38_HUMAN,tr|J3KT73|J3KT73_HUMAN,tr|J3QL01|J3QL01_HUMAN,tr|J3KSP2|J3KSP2_HUMAN" 4 1464.8307 1.41 90015 23061 3 1464.832874 489.2842 60S ribosomal protein L38 OS=Homo sapiens OX=9606 GN=RPL38 PE=1 SV=2 4.68 3529.6 - 351819 - - - 1.4841 - 2.214 0.458 - 295.7 1 2 1 0.0022 12 0 0 0 1.60E+07 1.14E+07 - - - 5.8487 0.9994 221125_WJC_METTL3_EV_vs_WT_F06.23062.23062.3 0.000372 16/44 K.IEEIKDFLLTAR.R "sp|P63173|RL38_HUMAN,tr|J3KT73|J3KT73_HUMAN,tr|J3QL01|J3QL01_HUMAN,tr|J3KSP2|J3KSP2_HUMAN" 4 1446.8082 1.41 90016 23062 3 1446.806264 483.2767 60S ribosomal protein L38 OS=Homo sapiens OX=9606 GN=RPL38 PE=1 SV=2 4.68 3529.7 - 329399 - - - -1.3589 - 2.754 0.343 - 320.8 1 2 1 -0.002 12 0 0 0 1.60E+07 1.14E+07 - - - 5.1716 1 221125_WJC_METTL3_EV_vs_WT_F06.23066.23066.4 2.25E-12 27/132 K.DTSNHFHVFVGDLSPEITTEDIK[136.11].S "sp|Q01085|TIAR_HUMAN,tr|C9JTN7|C9JTN7_HUMAN,tr|E7ETC0|E7ETC0_HUMAN,tr|H7BY49|H7BY49_HUMAN,tr|A6NKZ9|A6NKZ9_HUMAN,tr|E7ETJ9|E7ETJ9_HUMAN" 6 2608.2537 1.92 90018 23066 4 2608.254901 653.0707 Nucleolysin TIAR OS=Homo sapiens OX=9606 GN=TIAL1 PE=1 SV=1 4.42 3530.3 - 4.86E+06 - - - 0.475 - 4.086 0.664 - 548.6 1 2 0 0.0012 23 0 0 0 2.62E+08 1.36E+08 - - - 5.4611 0.9987 221125_WJC_METTL3_EV_vs_WT_F06.23067.23067.3 0.0046 6/124 K.ESESC[160.03]DC[160.03]LQGFQLTHSLGGGTGSGMGTLLISK.L "sp|Q9BVA1|TBB2B_HUMAN,sp|Q13885|TBB2A_HUMAN" 2 3326.5217 0.64 90019 23067 3 3326.518047 1109.8479 Tubulin beta-2B chain OS=Homo sapiens OX=9606 GN=TUBB2B PE=1 SV=1 4.65 3530.4 - 983631 - - - -1.1066 - 1.4 0.347 - 23.8 1 2 0 -0.0037 32 0 0 0 2.34E+07 3.65E+07 - - - 3.1818 1 221125_WJC_METTL3_EV_vs_WT_F06.23069.23069.4 3.60E-14 25/126 A.FYLPGLAPVNFC[160.03]DEEK[136.11]K[136.11]SDEC[160.03]K[136.11].A sp|Q99805|TM9S2_HUMAN 1 2669.2568 5.95 90021 23069 4 2669.258048 668.3215 Transmembrane 9 superfamily member 2 OS=Homo sapiens OX=9606 GN=TM9SF2 PE=1 SV=1 4.51 3530.6 - 860505 - - - 0.4765 - 4.66 0.689 - 310.3 1 1 1 0.0013 22 0 0 0 1.07E+08 1.80E+07 - - - 5.7263 0.9999 221125_WJC_METTL3_EV_vs_WT_F06.23071.23071.4 5.64E-07 24/126 K.EK[136.11]DILVLPLDLTDTGSHEAATK[136.11].A "sp|Q9Y394|DHRS7_HUMAN,tr|H0YJ66|H0YJ66_HUMAN,tr|H0YJE4|H0YJE4_HUMAN" 3 2381.2661 0.97 90023 23071 4 2381.270184 596.3238 Dehydrogenase\reductase SDR family member 7 OS=Homo sapiens OX=9606 GN=DHRS7 PE=1 SV=1 4.43 3530.8 - 590453 - - - 1.7272 - 4.44 0.605 - 495.7 1 2 1 0.0041 22 0 0 0 1.64E+07 1.69E+07 - - - 4.9785 0.9999 221125_WJC_METTL3_EV_vs_WT_F06.23077.23077.4 1.34E-08 27/120 R.VGRQELEIVIGDEHISFTTSK.L "sp|Q96A72|MGN2_HUMAN,sp|P61326|MGN_HUMAN,tr|F5H6P7|F5H6P7_HUMAN" 3 2357.2227 1.48 90027 23077 4 2357.22766 590.3129 Protein mago nashi homolog 2 OS=Homo sapiens OX=9606 GN=MAGOHB PE=1 SV=1 4.83 3531.6 - 1.13E+06 - - - 2.1084 - 5.031 0.601 - 554.2 1 2 1 0.005 21 0 0 0 1.56E+07 1.05E+07 - - - 4.9899 0.9998 221125_WJC_METTL3_EV_vs_WT_F06.23078.23078.4 4.14E-10 22/126 K.EKDILVLPLDLTDTGSHEAATK.A "sp|Q9Y394|DHRS7_HUMAN,tr|H0YJ66|H0YJ66_HUMAN,tr|H0YJE4|H0YJE4_HUMAN" 3 2365.2377 0.97 90028 23078 4 2365.243632 592.3167 Dehydrogenase\reductase SDR family member 7 OS=Homo sapiens OX=9606 GN=DHRS7 PE=1 SV=1 4.43 3531.7 - 580494 - - - 2.5203 - 3.664 0.569 - 360.3 1 2 1 0.006 22 0 0 0 1.65E+07 1.69E+07 - - - 4.6018 0.8437 221125_WJC_METTL3_EV_vs_WT_F06.23082.23082.4 0.248 6/186 K.ESESC[160.03]DC[160.03]LQGFQLTHSLGGGTGSGMGTLLISK[136.11].L "sp|Q9BVA1|TBB2B_HUMAN,sp|Q13885|TBB2A_HUMAN" 2 3334.5359 0.4 90030 23082 4 3334.542271 834.6413 Tubulin beta-2B chain OS=Homo sapiens OX=9606 GN=TUBB2B PE=1 SV=1 4.65 3532.3 - 1.24E+06 - - - 1.9022 - 1.272 0.121 - 13.6 1 2 0 0.0063 32 0 0 0 6.50E+06 1.64E+07 - - - 0.3501 1 221125_WJC_METTL3_EV_vs_WT_F06.23084.23084.3 3.39E-13 19/108 R.SATPVNC[160.03]EQPDILVSSTPINEGQTVLDK.V "sp|P82094|TMF1_HUMAN,tr|F8WF45|F8WF45_HUMAN,tr|A0A2R8Y7M0|A0A2R8Y7M0_HUMAN" 3 3011.4757 1.32 90032 23084 3 3011.485418 1004.8325 TATA element modulatory factor OS=Homo sapiens OX=9606 GN=TMF1 PE=1 SV=2 3.92 3532.5 - 434573 - - - 3.2114 - 4.033 0.665 - 209.6 1 2 0 0.0097 28 0 0 0 7.65E+06 5.81E+06 - - - 9.1597 0.9965 221125_WJC_METTL3_EV_vs_WT_F06.23085.23085.4 0.000399 13/108 R.KYLAEIVLIDDFSNKEHLK.E "sp|Q86SF2|GALT7_HUMAN,tr|H0YAH3|H0YAH3_HUMAN,tr|E9PBY3|E9PBY3_HUMAN" 3 2274.226 2.89 90033 23085 4 2274.233284 569.5638 N-acetylgalactosaminyltransferase 7 OS=Homo sapiens OX=9606 GN=GALNT7 PE=1 SV=1 5.48 3532.7 - 349045 - - - 3.2099 - 2.651 0.363 - 125.2 1 2 1 0.0073 19 0 0 0 5.27E+06 1.83E+06 - - - 2.7133 1 221125_WJC_METTL3_EV_vs_WT_F06.23087.23087.3 1.87E-09 30/88 K.DTSNHFHVFVGDLSPEITTEDIK.S "sp|Q01085|TIAR_HUMAN,tr|C9JTN7|C9JTN7_HUMAN,tr|E7ETC0|E7ETC0_HUMAN,tr|H7BY49|H7BY49_HUMAN,tr|A6NKZ9|A6NKZ9_HUMAN,tr|E7ETJ9|E7ETJ9_HUMAN" 6 2600.2395 1.63 90034 23087 3 2600.239858 867.7538 Nucleolysin TIAR OS=Homo sapiens OX=9606 GN=TIAL1 PE=1 SV=1 4.42 3532.9 - 2.78E+06 - - - 0.1523 - 5.321 0.691 - 1315.6 1 2 0 0.0004 23 0 0 0 6.56E+07 4.02E+07 - - - 10.1655 0.9995 221125_WJC_METTL3_EV_vs_WT_F06.23090.23090.3 3.41E-07 16/96 K.NPSLPSKLDPFESSDPFSSSSVSSK.G "sp|Q9UBC2|EP15R_HUMAN,tr|M0R3I1|M0R3I1_HUMAN,tr|M0R165|M0R165_HUMAN" 3 2625.2446 2.2 90036 23090 3 2625.254502 876.0888 Epidermal growth factor receptor substrate 15-like 1 OS=Homo sapiens OX=9606 GN=EPS15L1 PE=1 SV=1 4.56 3533.2 - 569697 - - - 3.7692 - 2.904 0.564 - 221 1 2 1 0.0099 25 0 0 0 7.83E+06 3.56E+06 - - - 7.278 1 221125_WJC_METTL3_EV_vs_WT_F06.23095.23095.3 1.26E-13 19/92 R.ELFIEEIQAGSQGQAGASDSPSAR.S "sp|P39880|CUX1_HUMAN,tr|A0A2R8Y852|A0A2R8Y852_HUMAN,tr|A0A2R8YDI1|A0A2R8YDI1_HUMAN" 3 2447.1565 1.84 90039 23095 3 2447.162113 816.7261 Homeobox protein cut-like 1 OS=Homo sapiens OX=9606 GN=CUX1 PE=1 SV=3 4 3533.9 - 1.31E+06 - - - 2.3096 - 3.939 0.672 - 356.5 1 2 0 0.0057 24 0 0 0 2.20E+07 1.19E+07 - - - 9.2147 0.9999 221125_WJC_METTL3_EV_vs_WT_F06.23096.23096.3 3.84E-09 20/92 R.ELFIEEIQAGSQGQAGASDSPSAR[166.11].S "sp|P39880|CUX1_HUMAN,tr|A0A2R8Y852|A0A2R8Y852_HUMAN,tr|A0A2R8YDI1|A0A2R8YDI1_HUMAN" 3 2457.1647 1.9 90040 23096 3 2457.175789 820.0622 Homeobox protein cut-like 1 OS=Homo sapiens OX=9606 GN=CUX1 PE=1 SV=3 4 3534 - 761336 - - - 4.5003 - 3.68 0.585 - 431.2 1 2 0 0.0111 24 0 0 0 2.20E+07 1.16E+07 - - - 8.0853 0.9989 221125_WJC_METTL3_EV_vs_WT_F06.23103.23103.3 0.0303 7/124 K.ESESC[160.03]DC[160.03]LQGFQLTHSLGGGTGSGMGTLLISK[136.11].L "sp|Q9BVA1|TBB2B_HUMAN,sp|Q13885|TBB2A_HUMAN" 2 3334.5359 0.64 90044 23103 3 3334.541498 1112.5193 Tubulin beta-2B chain OS=Homo sapiens OX=9606 GN=TUBB2B PE=1 SV=1 4.65 3534.9 - 1.51E+06 - - - 1.6704 - 1.475 0.373 - 34 1 2 0 0.0056 32 0 0 0 2.34E+07 3.65E+07 - - - 3.5912 0.9996 221125_WJC_METTL3_EV_vs_WT_F06.23104.23104.4 0.000211 15/102 R.TDYHILNDPELSFLDAHK[136.11].N sp|Q9P2D1|CHD7_HUMAN 1 2135.0415 1.24 90045 23104 4 2135.047894 534.7676 Chromodomain-helicase-DNA-binding protein 7 OS=Homo sapiens OX=9606 GN=CHD7 PE=1 SV=3 4.63 3535 - 312888 - - - 3.0018 - 2.439 0.399 - 91.1 1 2 0 0.0064 18 0 0 0 5.35E+06 4.32E+06 - - - 3.0025 0.9998 221125_WJC_METTL3_EV_vs_WT_F06.23107.23107.3 1.43E-07 15/92 K.NTPSPDVTLGTNPGTEDIQFPIQK[136.11].L "sp|Q8IX01|SUGP2_HUMAN,tr|M0R2Z9|M0R2Z9_HUMAN,tr|M0R3F6|M0R3F6_HUMAN" 3 2576.285 1.63 90046 23107 3 2576.290416 859.7689 SURP and G-patch domain-containing protein 2 OS=Homo sapiens OX=9606 GN=SUGP2 PE=1 SV=2 4.03 3535.6 - 883845 - - - 2.117 - 3.086 0.372 - 148.8 1 2 0 0.0055 24 0 0 0 4.01E+09 2.46E+09 - - - 5.3032 0.9989 221125_WJC_METTL3_EV_vs_WT_F06.23108.23108.3 4.32E-05 Dec-72 R.GLLQDDAHPTLVTYADHSK[136.11].L "sp|Q86U44|MTA70_HUMAN,tr|F5H6D8|F5H6D8_HUMAN,tr|H0YFV6|H0YFV6_HUMAN,tr|B4DTN4|B4DTN4_HUMAN" 4 2088.0367 0.06 90047 23108 3 2088.045377 697.0195 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 5.13 3535.7 - 296368 - - - 4.1398 - 2.507 0.375 - 167.5 1 2 0 0.0086 19 0 0 0 8.57E+05 1.35E+07 - - - 4.9765 0.9999 221125_WJC_METTL3_EV_vs_WT_F06.23109.23109.3 5.67E-07 20/104 R.NPATSVTSQGTQTLALQLQNAETQTER[166.11].E "sp|Q9C0C7|AMRA1_HUMAN,tr|H0YE34|H0YE34_HUMAN,tr|A0A075B6T1|A0A075B6T1_HUMAN" 3 2896.4402 0.55 90048 23109 3 2896.452351 966.4873 Activating molecule in BECN1-regulated autophagy protein 1 OS=Homo sapiens OX=9606 GN=AMBRA1 PE=1 SV=2 4.53 3535.8 - 351681 - - - 4.2027 - 3.983 0.594 - 420.3 1 2 0 0.0122 27 0 0 0 1.00E+07 1.82E+07 - - - 8.3387 0.9997 221125_WJC_METTL3_EV_vs_WT_F06.23110.23110.3 0.00193 11/112 K.AGPDLPSLPSHALEDEGWAAAAPSPGSAR.S sp|Q9H3Q1|BORG4_HUMAN 1 2826.3573 0.43 90049 23110 3 2826.365965 943.1264 Cdc42 effector protein 4 OS=Homo sapiens OX=9606 GN=CDC42EP4 PE=1 SV=1 4.31 3535.9 - 185533 - - - 3.0707 - 2.405 0.449 - 66.8 1 2 0 0.0087 29 0 0 0 2.77E+06 6.48E+06 - - - 5.5624 0.9993 221125_WJC_METTL3_EV_vs_WT_F06.23114.23114.3 2.35E-05 15/92 K.NTPSPDVTLGTNPGTEDIQFPIQK.L "sp|Q8IX01|SUGP2_HUMAN,tr|M0R2Z9|M0R2Z9_HUMAN,tr|M0R3F6|M0R3F6_HUMAN" 3 2568.2708 1.63 90051 23114 3 2568.281678 857.0975 SURP and G-patch domain-containing protein 2 OS=Homo sapiens OX=9606 GN=SUGP2 PE=1 SV=2 4.03 3536.4 - 1.31E+06 - - - 4.2503 - 3.216 0.382 - 157.2 1 2 0 0.0109 24 0 0 0 4.02E+09 2.46E+09 - - - 5.509 1 221125_WJC_METTL3_EV_vs_WT_F06.23115.23115.3 3.55E-11 15/104 R.NPATSVTSQGTQTLALQLQNAETQTER.E "sp|Q9C0C7|AMRA1_HUMAN,tr|H0YE34|H0YE34_HUMAN,tr|A0A075B6T1|A0A075B6T1_HUMAN" 3 2886.4319 0.55 90052 23115 3 2886.448849 963.1512 Activating molecule in BECN1-regulated autophagy protein 1 OS=Homo sapiens OX=9606 GN=AMBRA1 PE=1 SV=2 4.53 3536.5 - 316478 - - - 5.8692 - 4.118 0.654 - 191.6 1 2 0 0.0169 27 0 0 0 1.00E+07 1.82E+07 - - - 9.083 1 221125_WJC_METTL3_EV_vs_WT_F06.23117.23117.3 3.54E-12 24/60 R.HGNLEEAEHLLQDAIK.N sp|Q86UA1|PRP39_HUMAN 1 1815.9115 1.55 90054 23117 3 1815.911861 606.3111 Pre-mRNA-processing factor 39 OS=Homo sapiens OX=9606 GN=PRPF39 PE=1 SV=3 4.8 3536.8 - 716520 - - - 0.1845 - 3.918 0.666 - 1222 1 2 0 0.0003 16 0 0 0 1.13E+07 7.31E+06 - - - 9.469 0.9998 221125_WJC_METTL3_EV_vs_WT_F06.23124.23124.4 9.53E-11 23/96 K.AREGSEEDLDALEHMFR.Q sp|P31944|CASPE_HUMAN 1 2003.9007 385.03 90059 23124 4 2003.906817 501.9825 Caspase-14 OS=Homo sapiens OX=9606 GN=CASP14 PE=1 SV=2 4.35 3537.6 - 467351 - - - 3.0506 - 4.377 0.608 - 800.2 1 2 1 0.0061 17 0 0 0 6.66E+07 1.73E+05 - - - 5.0289 1 221125_WJC_METTL3_EV_vs_WT_F06.23127.23127.3 3.62E-10 25/100 K.QQPTQFINPETPGYVGFANLPNQVHR.K "sp|Q15019|SEPT2_HUMAN,tr|C9JFT1|C9JFT1_HUMAN,tr|C9JB25|C9JB25_HUMAN,tr|C9JT15|C9JT15_HUMAN,tr|C9J938|C9J938_HUMAN,tr|A0A1B0GXJ2|A0A1B0GXJ2_HUMAN,tr|C9JSE7|C9JSE7_HUMAN,tr|C9JZI2|C9JZI2_HUMAN,tr|F8WB65|F8WB65_HUMAN,tr|C9IZU3|C9IZU3_HUMAN,tr|C9JQJ4|C9JQJ4_HUMAN" 11 2951.4678 1.07 90062 23127 3 2951.476218 984.8299 Septin-2 OS=Homo sapiens OX=9606 GN=SEPTIN2 PE=1 SV=1 6.75 3538 - 360152 - - - 2.8389 - 3.944 0.685 - 442.9 1 2 0 0.0084 26 0 0 0 2.40E+07 2.24E+07 - - - 9.3317 1 221125_WJC_METTL3_EV_vs_WT_F06.23133.23133.4 1.17E-26 30/192 R.C[160.03]FGFVTYSNVEEADAAMAASPHAVDGNTVELKR.A sp|Q13151|ROA0_HUMAN 1 3555.6399 0.47 90066 23133 4 3555.644052 889.9172 Heterogeneous nuclear ribonucleoprotein A0 OS=Homo sapiens OX=9606 GN=HNRNPA0 PE=1 SV=1 4.5 3538.8 - 612146 - - - 1.1764 - 5.915 0.796 - 790.8 1 2 0 0.0042 33 0 0 0 5.09E+06 1.09E+07 - - - 6.6865 1 221125_WJC_METTL3_EV_vs_WT_F06.23134.23134.3 5.88E-17 26/100 K.QQPTQFINPETPGYVGFANLPNQVHR[166.11].K "sp|Q15019|SEPT2_HUMAN,tr|C9JFT1|C9JFT1_HUMAN,tr|C9JB25|C9JB25_HUMAN,tr|C9JT15|C9JT15_HUMAN,tr|C9J938|C9J938_HUMAN,tr|A0A1B0GXJ2|A0A1B0GXJ2_HUMAN,tr|C9JSE7|C9JSE7_HUMAN,tr|C9JZI2|C9JZI2_HUMAN,tr|F8WB65|F8WB65_HUMAN,tr|C9IZU3|C9IZU3_HUMAN,tr|C9JQJ4|C9JQJ4_HUMAN" 11 2961.4761 1.07 90067 23134 3 2961.487031 988.166 Septin-2 OS=Homo sapiens OX=9606 GN=SEPTIN2 PE=1 SV=1 6.75 3538.9 - 578575 - - - 3.688 - 4.449 0.679 - 514.5 1 2 0 0.0109 26 0 0 0 2.40E+07 2.24E+07 - - - 9.5413 1 221125_WJC_METTL3_EV_vs_WT_F06.23141.23141.3 3.74E-08 32/64 K.AREGSEEDLDALEHMFR.Q sp|P31944|CASPE_HUMAN 1 2003.9007 999 90072 23141 3 2003.907466 668.9742 Caspase-14 OS=Homo sapiens OX=9606 GN=CASP14 PE=1 SV=2 4.35 3539.8 - 1.49E+06 - - - 3.3744 - 5.169 0.656 - 1780.7 1 2 1 0.0068 17 0 0 0 3.92E+07 0.00E+00 - - - 10.0018 0.8343 221125_WJC_METTL3_EV_vs_WT_F06.23142.23142.4 0.0454 10/114 K.K[136.11]LDEDSLTK[136.11]QPEEVFDVLEK[136.11].L "sp|Q13043|STK4_HUMAN,tr|A0A087WYT4|A0A087WYT4_HUMAN,tr|F5H5B4|F5H5B4_HUMAN" 3 2385.2377 1.94 90073 23142 4 2385.247503 597.3167 Serine\threonine-protein kinase 4 OS=Homo sapiens OX=9606 GN=STK4 PE=1 SV=2 4.2 3539.9 - 298458 - - - 4.0939 - 1.885 0.213 - 33 1 2 1 0.0098 20 0 0 0 2.78E+06 1.44E+06 - - - 1.2892 1 221125_WJC_METTL3_EV_vs_WT_F06.23146.23146.3 6.68E-10 34/108 K.TPGAVNAC[160.03]HLSC[160.03]SALLQDNIADAVAC[160.03]AK.R sp|P61626|LYSC_HUMAN 1 2926.3735 999 90075 23146 3 2926.378058 976.4651 Lysozyme C OS=Homo sapiens OX=9606 GN=LYZ PE=1 SV=1 5.18 3540.5 - 1.72E+06 - - - 1.5415 - 5.772 0.703 - 1301.8 1 2 0 0.0045 28 0 0 0 3.10E+07 0.00E+00 - - - 10.4096 0.9999 221125_WJC_METTL3_EV_vs_WT_F06.23147.23147.3 4.35E-09 25/100 K.GGVSAVAGGVTAVGSAVVNK[136.11]VPLTGK[136.11].K sp|Q8WUH6|TM263_HUMAN 1 2310.3242 0.85 90076 23147 3 2310.328262 771.1153 Transmembrane protein 263 OS=Homo sapiens OX=9606 GN=TMEM263 PE=1 SV=1 10 3540.6 - 1.16E+06 - - - 1.7604 - 4.321 0.548 - 525.6 1 2 1 0.0041 26 0 0 0 1.43E+07 1.68E+07 - - - 8.0155 0.9994 221125_WJC_METTL3_EV_vs_WT_F06.23149.23149.4 0.00093 15/156 R.YC[160.03]QVSFQDDHVSLESAFTVRPLPDEPK.H "sp|A6NHR9|SMHD1_HUMAN,tr|J3KTL8|J3KTL8_HUMAN" 2 3163.4921 0.63 90078 23149 4 3163.506543 791.8803 Structural maintenance of chromosomes flexible hinge domain-containing protein 1 OS=Homo sapiens OX=9606 GN=SMCHD1 PE=1 SV=2 4.43 3540.9 - 753327 - - - 4.5766 - 3.2 0.457 - 74.7 1 2 0 0.0145 27 0 0 0 7.62E+06 1.21E+07 - - - 3.5637 0.9984 221125_WJC_METTL3_EV_vs_WT_F06.23151.23151.3 9.16E-09 21/108 K.VSGGTPIK[136.11]IEDPNQFVPLNTNPNEVLEK[136.11].R sp|Q9UEY8|ADDG_HUMAN 1 3064.6052 0.73 90080 23151 3 3064.614591 1022.5423 Gamma-adducin OS=Homo sapiens OX=9606 GN=ADD3 PE=1 SV=1 4.41 3541.1 - 474722 - - - 3.0705 - 3.949 0.329 - 267.1 1 2 1 0.0094 28 0 0 0 3.50E+06 4.78E+06 - - - 5.3653 0.9999 221125_WJC_METTL3_EV_vs_WT_F06.23157.23157.3 0.000384 24/100 K.GGVSAVAGGVTAVGSAVVNKVPLTGK.K sp|Q8WUH6|TM263_HUMAN 1 2294.2958 0.85 90084 23157 3 2294.299865 765.7725 Transmembrane protein 263 OS=Homo sapiens OX=9606 GN=TMEM263 PE=1 SV=1 10 3541.8 - 1.66E+06 - - - 1.774 - 4.387 0.546 - 451 1 2 1 0.0041 26 0 0 0 1.42E+07 1.67E+07 - - - 8.0281 1 221125_WJC_METTL3_EV_vs_WT_F06.23159.23159.4 1.66E-07 16/108 R.GLLQDDAHPTLVTYADHSK[136.11].L "sp|Q86U44|MTA70_HUMAN,tr|F5H6D8|F5H6D8_HUMAN,tr|H0YFV6|H0YFV6_HUMAN,tr|B4DTN4|B4DTN4_HUMAN" 4 2088.0367 0.03 90086 23159 4 2088.040537 523.0165 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 5.13 3542 - 932792 - - - 1.8218 - 3.067 0.577 - 229.9 1 2 0 0.0038 19 0 0 0 8.47E+05 2.54E+07 - - - 4.6263 0.9422 221125_WJC_METTL3_EV_vs_WT_F06.23169.23169.3 5.40E-06 Dec-84 R.NKEIQDLEESFVPVAAPLGHPR.E sp|Q9NPE2|NGRN_HUMAN 1 2445.2652 1.99 90094 23169 3 2445.284026 816.0957 Neugrin OS=Homo sapiens OX=9606 GN=NGRN PE=1 SV=2 4.83 3543.3 - 324777 - - - 7.6896 - 2.746 0.34 - 78.8 1 2 1 0.0188 22 0 0 0 4.90E+06 2.47E+06 - - - 4.7203 0.9925 221125_WJC_METTL3_EV_vs_WT_F06.23171.23171.4 1.47E-05 13/108 R.MALENYLAALQSDPPRPHR.L sp|Q06481|APLP2_HUMAN 1 2178.1004 1.67 90096 23171 4 2178.108495 545.5324 Amyloid beta precursor like protein 2 OS=Homo sapiens OX=9606 GN=APLP2 PE=1 SV=2 6.51 3543.5 - 180144 - - - 3.7133 - 2.761 0.268 - 49.7 1 2 0 0.0081 19 0 0 0 5.46E+06 3.26E+06 - - - 1.9 1 221125_WJC_METTL3_EV_vs_WT_F06.23176.23176.3 1.14E-10 24/72 A.TISANGDK[136.11]EIGNIISDAMK[136.11].K "sp|P10809|CH60_HUMAN,tr|A0A7I2V599|A0A7I2V599_HUMAN,tr|E7EXB4|E7EXB4_HUMAN,tr|A0A7I2YQ71|A0A7I2YQ71_HUMAN,tr|E7ESH4|E7ESH4_HUMAN,tr|A0A7I2V5M1|A0A7I2V5M1_HUMAN,tr|A0A7I2V5K3|A0A7I2V5K3_HUMAN,tr|A0A7I2V369|A0A7I2V369_HUMAN" 8 1992.0169 1.3 90099 23176 3 1992.025791 665.0129 "60 kDa heat shock protein, mitochondrial OS=Homo sapiens OX=9606 GN=HSPD1 PE=1 SV=2" 4.56 3544.1 - 713333 - - - 4.4854 - 3.68 0.642 - 356 1 1 1 0.0089 19 0 0 0 1.03E+07 7.96E+06 - - - 8.8962 0.9983 221125_WJC_METTL3_EV_vs_WT_F06.23177.23177.4 1.51E-07 19/132 R.K[136.11]NNFSDTGNFGFGIQEHIDLGIK[136.11].Y "sp|P62913|RL11_HUMAN,tr|Q5VVC8|Q5VVC8_HUMAN" 2 2566.2787 0.89 90100 23177 4 2567.288309 642.577 60S ribosomal protein L11 OS=Homo sapiens OX=9606 GN=RPL11 PE=1 SV=2 5.38 3544.2 - 1.91E+06 - - - 393.4128 - 3.566 0.559 - 177.3 1 2 0 1.0096 23 0 0 0 3.59E+08 4.03E+08 - - - 4.2238 0.9998 221125_WJC_METTL3_EV_vs_WT_F06.23181.23181.3 1.59E-05 11/132 K.AGSALPGFANSPAGSTSVVLVPPAHGTLVPDGNK.A "sp|O15027|SC16A_HUMAN,tr|A0A3F2YNX0|A0A3F2YNX0_HUMAN,tr|A0A3F2YNZ0|A0A3F2YNZ0_HUMAN,tr|F1T0I1|F1T0I1_HUMAN" 4 3184.6517 2 90104 23181 3 3184.660857 1062.5578 Protein transport protein Sec16A OS=Homo sapiens OX=9606 GN=SEC16A PE=1 SV=4 6.79 3544.7 - 492492 - - - 2.8826 - 2.42 0.467 - 39.5 1 2 0 0.0092 34 0 0 0 3.23E+06 1.61E+06 - - - 5.7773 1 221125_WJC_METTL3_EV_vs_WT_F06.23182.23182.3 2.10E-07 13/100 K.QQFVEYDKNSDDTVTWDEYNIQMYDR.V "sp|Q14257|RCN2_HUMAN,tr|H0YL43|H0YL43_HUMAN" 2 3301.4146 0.8 90105 23182 3 3301.411715 1101.4788 Reticulocalbin-2 OS=Homo sapiens OX=9606 GN=RCN2 PE=1 SV=1 3.85 3544.9 - 492463 - - - -0.8748 - 2.993 0.675 - 167.7 1 2 1 -0.0029 26 0 0 0 4.39E+06 5.51E+06 - - - 8.5869 0.9884 221125_WJC_METTL3_EV_vs_WT_F06.23184.23184.4 0.00107 11/150 K.QQPTQFINPETPGYVGFANLPNQVHR.K "sp|Q15019|SEPT2_HUMAN,tr|C9JFT1|C9JFT1_HUMAN,tr|C9JB25|C9JB25_HUMAN,tr|C9JT15|C9JT15_HUMAN,tr|C9J938|C9J938_HUMAN,tr|A0A1B0GXJ2|A0A1B0GXJ2_HUMAN,tr|C9JSE7|C9JSE7_HUMAN,tr|C9JZI2|C9JZI2_HUMAN,tr|F8WB65|F8WB65_HUMAN,tr|C9IZU3|C9IZU3_HUMAN,tr|C9JQJ4|C9JQJ4_HUMAN" 11 2951.4678 0.31 90107 23184 4 2951.487446 738.8742 Septin-2 OS=Homo sapiens OX=9606 GN=SEPTIN2 PE=1 SV=1 6.75 3545.1 - 524673 - - - 6.6431 - 2.211 0.36 - 37 1 2 0 0.0196 26 0 0 0 1.84E+06 5.93E+06 - - - 2.6043 0.9994 221125_WJC_METTL3_EV_vs_WT_F06.23186.23186.4 4.31E-06 16/90 R.EKEHYC[160.03]LADLASLMDK.T "sp|Q92552|RT27_HUMAN,tr|E5RJ73|E5RJ73_HUMAN" 2 1921.8914 1.2 90109 23186 4 1921.89885 481.4801 "28S ribosomal protein S27, mitochondrial OS=Homo sapiens OX=9606 GN=MRPS27 PE=1 SV=3" 4.75 3545.4 - 267149 - - - 3.8842 - 2.585 0.531 - 211.1 1 2 1 0.0075 16 0 0 0 1.49E+07 1.23E+07 - - - 4.1803 1 221125_WJC_METTL3_EV_vs_WT_F06.23194.23194.3 2.75E-09 17/100 K.K[136.11]ADVSEQVSNGPVESVTLENSPLVWK[136.11].E "sp|Q9NRL3|STRN4_HUMAN,tr|M0R0P4|M0R0P4_HUMAN,tr|F5GYK2|F5GYK2_HUMAN,tr|M0R2A7|M0R2A7_HUMAN,tr|M0QYS2|M0QYS2_HUMAN,tr|M0R0W8|M0R0W8_HUMAN,tr|M0QXN2|M0QXN2_HUMAN" 7 2827.4575 3.4 90115 23194 3 2827.460271 943.4931 Striatin-4 OS=Homo sapiens OX=9606 GN=STRN4 PE=1 SV=2 4.41 3546.4 - 348041 - - - 0.9963 - 3.746 0.671 - 245.8 1 2 0 0.0028 26 0 0 0 1.12E+07 3.28E+06 - - - 9.0586 0.9999 221125_WJC_METTL3_EV_vs_WT_F06.23196.23196.4 3.86E-07 20/114 R.R[166.11]K[136.11]DGVFLYFEDNAGVIVNNK[136.11].G "sp|P62829|RL23_HUMAN,tr|J3KT29|J3KT29_HUMAN,tr|J3KTJ3|J3KTJ3_HUMAN" 3 2323.2171 1.34 90116 23196 4 2323.2197 581.8116 60S ribosomal protein L23 OS=Homo sapiens OX=9606 GN=RPL23 PE=1 SV=1 6.12 3546.6 - 1.30E+06 - - - 1.1187 - 3.419 0.544 - 347.8 1 2 1 0.0026 20 0 0 0 7.98E+07 5.93E+07 - - - 4.3713 0.9999 221125_WJC_METTL3_EV_vs_WT_F06.23199.23199.3 2.27E-09 17/60 R.EK[136.11]EHYC[160.03]LADLASLMDK[136.11].T "sp|Q92552|RT27_HUMAN,tr|E5RJ73|E5RJ73_HUMAN" 2 1937.9198 1.11 90118 23199 3 1937.922898 646.9805 "28S ribosomal protein S27, mitochondrial OS=Homo sapiens OX=9606 GN=MRPS27 PE=1 SV=3" 4.75 3546.9 - 2.23E+06 - - - 1.6064 - 3.118 0.608 - 435.7 1 2 1 0.0031 16 0 0 0 3.52E+07 3.18E+07 - - - 8.2356 1 221125_WJC_METTL3_EV_vs_WT_F06.23201.23201.4 4.63E-14 33/186 R.SPGVQPQLVLGGAAQTASLGTATAVQTGTPQR[166.11].T sp|O00268|TAF4_HUMAN 1 3071.6239 1.19 90120 23201 4 3071.626712 768.9133 Transcription initiation factor TFIID subunit 4 OS=Homo sapiens OX=9606 GN=TAF4 PE=1 SV=2 9.47 3547.2 - 1.07E+06 - - - 0.9168 - 5.955 0.661 - 782.7 1 2 0 0.0028 32 0 0 0 1.19E+07 9.95E+06 - - - 5.5173 0.9986 221125_WJC_METTL3_EV_vs_WT_F06.23203.23203.4 3.30E-09 17/114 R.HVAEVLEYTK[136.11]DEQLESLFQR[166.11].T "sp|P05198|IF2A_HUMAN,tr|H0YJS4|H0YJS4_HUMAN,tr|G3V4T5|G3V4T5_HUMAN" 3 2451.2401 5.1 90122 23203 4 2451.253072 613.8173 Eukaryotic translation initiation factor 2 subunit 1 OS=Homo sapiens OX=9606 GN=EIF2S1 PE=1 SV=3 4.57 3547.5 - 460715 - - - 5.3022 - 3.456 0.544 - 211.7 1 2 1 0.013 20 0 0 0 5.73E+07 1.12E+07 - - - 4.372 0.9858 221125_WJC_METTL3_EV_vs_WT_F06.23208.23208.3 0.0376 13/60 R.DGLK[136.11]LMLLLEVISGER[166.11].L "sp|O43707|ACTN4_HUMAN,sp|P12814|ACTN1_HUMAN,tr|A0A804HK61|A0A804HK61_HUMAN,tr|A0A804HIN7|A0A804HIN7_HUMAN,tr|G3V5M4|G3V5M4_HUMAN,tr|A0A804HLF4|A0A804HLF4_HUMAN,tr|A0A804HIY0|A0A804HIY0_HUMAN,tr|A0A7I2V4Y4|A0A7I2V4Y4_HUMAN,tr|A0A804HII9|A0A804HII9_HUMAN,tr|A0A804HJQ9|A0A804HJQ9_HUMAN,tr|F5GXS2|F5GXS2_HUMAN,tr|A0A804HKE2|A0A804HKE2_HUMAN,tr|G3V2N5|G3V2N5_HUMAN,tr|A0A804HLD0|A0A804HLD0_HUMAN,tr|H7C144|H7C144_HUMAN" 15 1803.0295 0 90125 23208 3 1803.032699 602.0171 Alpha-actinin-4 OS=Homo sapiens OX=9606 GN=ACTN4 PE=1 SV=2 4.68 3548 - 3.43E+06 - - - 1.787 - 2.064 0.223 - 167.8 1 2 1 0.0032 16 0 0 0 9.07E+05 6.36E+08 - - - 2.8847 1 221125_WJC_METTL3_EV_vs_WT_F06.23210.23210.4 7.09E-13 25/114 R.TREGNDLYHEMIESGVINLK.D "sp|P06576|ATPB_HUMAN,tr|F8W079|F8W079_HUMAN,tr|H0YI37|H0YI37_HUMAN,tr|F8W0P7|F8W0P7_HUMAN,tr|H0YH81|H0YH81_HUMAN" 5 2317.1372 1.84 90127 23210 4 2317.139163 580.2916 "ATP synthase subunit beta, mitochondrial OS=Homo sapiens OX=9606 GN=ATP5F1B PE=1 SV=3" 4.83 3548.2 - 1.54E+06 - - - 0.8273 - 3.746 0.688 - 376.2 1 2 1 0.0019 20 0 0 0 3.14E+08 1.71E+08 - - - 5.6554 1 221125_WJC_METTL3_EV_vs_WT_F06.23211.23211.3 1.14E-07 21/88 R.KQPAGNYSLSSVLPNAPDMAQFK.Q sp|Q9NP61|ARFG3_HUMAN 1 2462.2264 1.24 90128 23211 3 2462.228307 821.7494 ADP-ribosylation factor GTPase-activating protein 3 OS=Homo sapiens OX=9606 GN=ARFGAP3 PE=1 SV=1 8.5 3548.4 - 967767 - - - 0.7765 - 3.499 0.531 - 375.2 1 2 0 0.0019 23 0 0 0 3.22E+08 2.59E+08 - - - 7.3978 0.9999 221125_WJC_METTL3_EV_vs_WT_F06.23213.23213.3 9.49E-06 15/80 K.AVGGLGKLGKDAVEDLESVGK.G sp|P81605|DCD_HUMAN 1 2041.1055 17.53 90130 23213 3 2041.105808 681.3758 Dermcidin OS=Homo sapiens OX=9606 GN=DCD PE=1 SV=2 4.78 3548.6 - 423880 - - - 0.1338 - 3.063 0.499 - 210.9 1 2 2 0.0003 21 0 0 0 7.48E+06 4.27E+05 - - - 6.787 1 221125_WJC_METTL3_EV_vs_WT_F06.23217.23217.4 7.94E-10 24/114 R.TR[166.11]EGNDLYHEMIESGVINLK[136.11].D "sp|P06576|ATPB_HUMAN,tr|F8W079|F8W079_HUMAN,tr|H0YI37|H0YI37_HUMAN,tr|F8W0P7|F8W0P7_HUMAN,tr|H0YH81|H0YH81_HUMAN" 5 2335.1597 1.84 90132 23217 4 2335.158527 584.7972 "ATP synthase subunit beta, mitochondrial OS=Homo sapiens OX=9606 GN=ATP5F1B PE=1 SV=3" 4.83 3549.1 - 1.92E+06 - - - -0.5092 - 3.429 0.64 - 351.1 1 2 1 -0.0012 20 0 0 0 3.14E+08 1.71E+08 - - - 5.2082 0.9997 221125_WJC_METTL3_EV_vs_WT_F06.23218.23218.4 3.03E-05 17/90 R.EK[136.11]EHYC[160.03]LADLASLMDK[136.11].T "sp|Q92552|RT27_HUMAN,tr|E5RJ73|E5RJ73_HUMAN" 2 1937.9198 1.2 90133 23218 4 1937.919544 485.4872 "28S ribosomal protein S27, mitochondrial OS=Homo sapiens OX=9606 GN=MRPS27 PE=1 SV=3" 4.75 3549.2 - 1.48E+06 - - - -0.1244 - 3.142 0.43 - 291.1 1 2 1 -0.0002 16 0 0 0 1.49E+07 1.23E+07 - - - 3.3719 1 221125_WJC_METTL3_EV_vs_WT_F06.23219.23219.3 1.58E-17 37/124 R.SPGVQPQLVLGGAAQTASLGTATAVQTGTPQR[166.11].T sp|O00268|TAF4_HUMAN 1 3071.6239 1.86 90134 23219 3 3071.629003 1024.8819 Transcription initiation factor TFIID subunit 4 OS=Homo sapiens OX=9606 GN=TAF4 PE=1 SV=2 9.47 3549.3 - 1.81E+06 - - - 1.6626 - 6.706 0.706 - 1675.3 1 2 0 0.0051 32 0 0 0 4.95E+07 2.66E+07 - - - 10.7879 1 221125_WJC_METTL3_EV_vs_WT_F06.23220.23220.3 5.49E-16 27/76 R.TREGNDLYHEMIESGVINLK.D "sp|P06576|ATPB_HUMAN,tr|F8W079|F8W079_HUMAN,tr|H0YI37|H0YI37_HUMAN,tr|F8W0P7|F8W0P7_HUMAN,tr|H0YH81|H0YH81_HUMAN" 5 2317.1372 1.6 90135 23220 3 2317.135268 773.3864 "ATP synthase subunit beta, mitochondrial OS=Homo sapiens OX=9606 GN=ATP5F1B PE=1 SV=3" 4.83 3549.4 - 1.80E+06 - - - -0.8536 - 4.777 0.654 - 879.6 1 2 1 -0.002 20 0 0 0 2.43E+08 1.52E+08 - - - 9.6248 1 221125_WJC_METTL3_EV_vs_WT_F06.23221.23221.3 6.52E-11 24/88 R.KNNFSDTGNFGFGIQEHIDLGIK.Y "sp|P62913|RL11_HUMAN,tr|Q5VVC8|Q5VVC8_HUMAN" 2 2550.2503 0.02 90136 23221 3 2550.267202 851.0907 60S ribosomal protein L11 OS=Homo sapiens OX=9606 GN=RPL11 PE=1 SV=2 5.38 3549.6 - 1.02E+06 - - - 6.6268 - 4.158 0.627 - 329.6 1 2 0 0.0169 23 0 0 0 8.25E+07 3.46E+09 - - - 8.8688 1 221125_WJC_METTL3_EV_vs_WT_F06.23222.23222.3 2.82E-09 18/112 K.SSSAGFSFGTGVINSTPAPANTIVTSENK.S sp|P49790|NU153_HUMAN 1 2840.3828 1.71 90137 23222 3 2840.381317 947.8016 Nuclear pore complex protein Nup153 OS=Homo sapiens OX=9606 GN=NUP153 PE=1 SV=2 5.72 3549.7 - 968729 - - - -0.5334 - 3.406 0.641 - 196.9 1 2 0 -0.0015 29 0 0 0 4.64E+07 2.72E+07 - - - 8.5056 1 221125_WJC_METTL3_EV_vs_WT_F06.23228.23228.4 4.65E-18 38/138 K.DYALHWLVLGTHTSDEQNHLVVAR[166.11].V "sp|Q16576|RBBP7_HUMAN,tr|C9J7L0|C9J7L0_HUMAN,tr|E9PC52|E9PC52_HUMAN" 3 2783.4019 1.29 90141 23228 4 2783.400931 696.8577 Histone-binding protein RBBP7 OS=Homo sapiens OX=9606 GN=RBBP7 PE=1 SV=1 5.73 3550.5 - 2.99E+06 - - - -0.3417 - 6.383 0.724 - 1308.9 1 2 0 -0.0009 24 0 0 0 1.42E+08 1.10E+08 - - - 6.1224 1 221125_WJC_METTL3_EV_vs_WT_F06.23229.23229.4 9.36E-18 36/138 K.DYALHWLVLGTHTSDEQNHLVVAR.V "sp|Q16576|RBBP7_HUMAN,tr|C9J7L0|C9J7L0_HUMAN,tr|E9PC52|E9PC52_HUMAN" 3 2773.3936 1.29 90142 23229 4 2773.389777 694.3557 Histone-binding protein RBBP7 OS=Homo sapiens OX=9606 GN=RBBP7 PE=1 SV=1 5.73 3550.6 - 2.46E+06 - - - -1.3828 - 5.398 0.719 - 1024 1 2 0 -0.0038 24 0 0 0 1.42E+08 1.10E+08 - - - 6.0243 1 221125_WJC_METTL3_EV_vs_WT_F06.23230.23230.3 1.82E-11 25/88 R.K[136.11]QPAGNYSLSSVLPNAPDMAQFK[136.11].Q sp|Q9NP61|ARFG3_HUMAN 1 2478.2548 1.24 90143 23230 3 2478.25371 827.0922 ADP-ribosylation factor GTPase-activating protein 3 OS=Homo sapiens OX=9606 GN=ARFGAP3 PE=1 SV=1 8.5 3550.7 - 1.93E+06 - - - -0.4378 - 4.46 0.617 - 503.5 1 2 0 -0.0011 23 0 0 0 3.22E+08 2.59E+08 - - - 8.9262 1 221125_WJC_METTL3_EV_vs_WT_F06.23233.23233.4 3.64E-11 22/156 R.HGGLALQPGPPGLHPFPFHPSLGPLER.E sp|P54259|ATN1_HUMAN 1 2824.4925 11.07 90146 23233 4 2824.490631 707.1304 Atrophin-1 OS=Homo sapiens OX=9606 GN=ATN1 PE=1 SV=3 7.03 3551 - 520204 - - - -0.6752 - 4.188 0.6 - 266 1 2 0 -0.0019 27 0 0 0 1.95E+07 1.76E+06 - - - 4.896 1 221125_WJC_METTL3_EV_vs_WT_F06.23241.23241.3 2.43E-10 23/76 R.TR[166.11]EGNDLYHEMIESGVINLK[136.11].D "sp|P06576|ATPB_HUMAN,tr|F8W079|F8W079_HUMAN,tr|H0YI37|H0YI37_HUMAN,tr|F8W0P7|F8W0P7_HUMAN,tr|H0YH81|H0YH81_HUMAN" 5 2335.1597 1.6 90150 23241 3 2335.159018 779.3938 "ATP synthase subunit beta, mitochondrial OS=Homo sapiens OX=9606 GN=ATP5F1B PE=1 SV=3" 4.83 3552.1 - 4.55E+06 - - - -0.2989 - 4.206 0.745 - 645.4 1 2 1 -0.0007 20 0 0 0 2.45E+08 1.53E+08 - - - 10.3308 0.9998 221125_WJC_METTL3_EV_vs_WT_F06.23245.23245.3 3.77E-07 18/84 K.DSGPLPTPPGVSLLGEPPK[136.11]DYR[166.11].L "tr|E9PAU2|E9PAU2_HUMAN,tr|A0A087WZ13|A0A087WZ13_HUMAN" 2 2309.2022 1.19 90154 23245 3 2309.20286 770.7414 Ribonucleoprotein PTB-binding 1 OS=Homo sapiens OX=9606 GN=RAVER1 PE=1 SV=1 4.56 3552.6 - 717340 - - - 0.272 - 2.543 0.473 - 218 1 2 1 0.0006 22 0 0 0 1.77E+08 1.48E+08 - - - 6.0261 1 221125_WJC_METTL3_EV_vs_WT_F06.23249.23249.3 2.30E-11 26/104 K.DHTPSQELALTQSVGGDSSADR[166.11]LFPPQ.W "sp|Q86U44|MTA70_HUMAN,tr|H0YFV6|H0YFV6_HUMAN" 2 2862.3659 0 90156 23249 3 2862.368868 955.1293 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 4.22 3553.1 - 1.84E+06 - - - 1.0194 - 4.46 0.616 - 294.4 1 1 1 0.0029 27 0 0 0 1.30E+05 6.33E+07 - - - 8.8468 0.9999 221125_WJC_METTL3_EV_vs_WT_F06.23250.23250.4 1.95E-08 13/114 R.GFAFVTFDDHDSVDKIVIQK.Y "sp|Q32P51|RA1L2_HUMAN,sp|P09651|ROA1_HUMAN,tr|A0A7I2YQX9|A0A7I2YQX9_HUMAN,tr|F8VZ49|F8VZ49_HUMAN,tr|A0A7I2V3R8|A0A7I2V3R8_HUMAN,tr|F8VTQ5|F8VTQ5_HUMAN,tr|F8W6I7|F8W6I7_HUMAN,tr|H0YH80|H0YH80_HUMAN,tr|A0A7I2V2L6|A0A7I2V2L6_HUMAN,tr|A0A7I2V3W0|A0A7I2V3W0_HUMAN,tr|A0A2R8Y4L2|A0A2R8Y4L2_HUMAN" 11 2280.1426 0.9 90157 23250 4 2280.139053 571.0429 Heterogeneous nuclear ribonucleoprotein A1-like 2 OS=Homo sapiens OX=9606 GN=HNRNPA1L2 PE=2 SV=2 4.56 3553.2 - 835066 - - - -1.5771 - 2.673 0.601 - 63.1 1 2 1 -0.0036 20 0 0 0 2.25E+07 2.49E+07 - - - 4.7848 1 221125_WJC_METTL3_EV_vs_WT_F06.23252.23252.3 2.78E-10 19/80 K.R[166.11]NQDLAPNSAEQASILSLVTK[136.11].L "sp|Q12905|ILF2_HUMAN,tr|B4DY09|B4DY09_HUMAN,tr|X6R6Z1|X6R6Z1_HUMAN,tr|A0A0A0MRL0|A0A0A0MRL0_HUMAN" 4 2272.2142 2.83 90159 23252 3 2272.213664 758.412 Interleukin enhancer-binding factor 2 OS=Homo sapiens OX=9606 GN=ILF2 PE=1 SV=2 6.07 3553.5 - 790728 - - - -0.2333 - 3.751 0.608 - 288.4 1 2 0 -0.0005 21 0 0 0 2.39E+07 8.46E+06 - - - 8.4879 1 221125_WJC_METTL3_EV_vs_WT_F06.23259.23259.3 1.56E-15 22/84 R.DYEVSDSAPHLEGLAEFQENVR.K sp|Q9HBM1|SPC25_HUMAN 1 2504.1456 1.99 90164 23259 3 2504.144318 835.7225 Kinetochore protein Spc25 OS=Homo sapiens OX=9606 GN=SPC25 PE=1 SV=1 4.08 3554.4 - 1.08E+06 - - - -0.4968 - 3.899 0.748 - 383.5 1 2 0 -0.0012 22 0 0 0 1.06E+07 5.36E+06 - - - 10.1052 1 221125_WJC_METTL3_EV_vs_WT_F06.23260.23260.4 3.77E-16 29/222 K.GILGYTEHQVVSSDFNSDTHSSTFDAGAGIALNDHFVK[136.11].L "sp|P04406|G3P_HUMAN,tr|E7EUT5|E7EUT5_HUMAN" 2 4043.9017 1.18 90165 23260 4 4043.902457 1011.9827 Glyceraldehyde-3-phosphate dehydrogenase OS=Homo sapiens OX=9606 GN=GAPDH PE=1 SV=3 4.7 3554.5 - 947015 - - - 0.1862 - 4.762 0.755 - 308.7 1 2 0 0.0008 38 0 0 0 2.88E+07 2.45E+07 - - - 6.2524 1 221125_WJC_METTL3_EV_vs_WT_F06.23261.23261.2 1.77E-10 20/46 R.NGPGFHNDIDSNSTIQEILIPASK.V sp|Q96I24|FUBP3_HUMAN 1 2566.2663 3.09 90166 23261 2 2566.265065 1284.1404 Far upstream element-binding protein 3 OS=Homo sapiens OX=9606 GN=FUBP3 PE=1 SV=2 4.54 3554.6 - 869008 - - - -0.4992 - 3.87 0.731 - 398.1 1 2 0 -0.0013 24 0 0 0 6.57E+07 2.13E+07 - - - 7.7668 1 221125_WJC_METTL3_EV_vs_WT_F06.23265.23265.3 3.40E-07 21/112 K.SSSAGFSFGTGVINSTPAPANTIVTSENK[136.11].S sp|P49790|NU153_HUMAN 1 2848.397 1.71 90168 23265 3 2848.39828 950.473 Nuclear pore complex protein Nup153 OS=Homo sapiens OX=9606 GN=NUP153 PE=1 SV=2 5.72 3555.2 - 1.38E+06 - - - 0.4381 - 4.02 0.563 - 302.5 1 2 0 0.0012 29 0 0 0 4.64E+07 2.72E+07 - - - 8.0174 0.9932 221125_WJC_METTL3_EV_vs_WT_F06.23266.23266.3 3.88E-05 16/88 R.EGIAMDQLLSQSLPNDGDEK[136.11]YEK[136.11].T sp|Q9BRP1|PDD2L_HUMAN 1 2595.2345 0.001 90169 23266 3 2596.237896 866.0854 Programmed cell death protein 2-like OS=Homo sapiens OX=9606 GN=PDCD2L PE=1 SV=1 4.02 3555.3 - 1.57E+06 - - - 386.6252 - 3.484 0.403 - 169.2 1 2 1 1.0034 23 0 0 0 0.00E+00 3.19E+07 - - - 5.6833 1 221125_WJC_METTL3_EV_vs_WT_F06.23267.23267.3 2.30E-13 19/112 K.DGTVTAGNASGVADGAGAVIIASEDAVKK.H "sp|P42765|THIM_HUMAN,tr|K7EME0|K7EME0_HUMAN,tr|A0A0B4J2A4|A0A0B4J2A4_HUMAN" 3 2643.3352 2.19 90170 23267 3 2643.334255 882.119 "3-ketoacyl-CoA thiolase, mitochondrial OS=Homo sapiens OX=9606 GN=ACAA2 PE=1 SV=2" 4.23 3555.4 - 754835 - - - -0.3401 - 4.192 0.642 - 263.2 1 2 0 -0.0009 29 0 0 0 1.32E+07 6.02E+06 - - - 8.9946 1 221125_WJC_METTL3_EV_vs_WT_F06.23271.23271.3 9.04E-17 35/108 K.QPIPASSMPQQIGIPTSSLTQVVHSAGR.R "sp|Q9H4A3|WNK1_HUMAN,tr|F5GWT4|F5GWT4_HUMAN,tr|A0A6Q8PFM0|A0A6Q8PFM0_HUMAN,tr|H0YH68|H0YH68_HUMAN" 4 2886.5022 1.75 90172 23271 3 2886.500836 963.1747 Serine\threonine-protein kinase WNK1 OS=Homo sapiens OX=9606 GN=WNK1 PE=1 SV=2 9.76 3555.9 - 2.01E+06 - - - -0.4642 - 5.075 0.669 - 670.3 1 2 0 -0.0013 28 0 0 0 5.77E+07 3.29E+07 - - - 9.7353 0.9989 221125_WJC_METTL3_EV_vs_WT_F06.23273.23273.3 1.37E-05 19/84 K.DSGPLPTPPGVSLLGEPPKDYR.L "tr|E9PAU2|E9PAU2_HUMAN,tr|A0A087WZ13|A0A087WZ13_HUMAN" 2 2291.1798 1.2 90174 23273 3 2291.182987 764.7339 Ribonucleoprotein PTB-binding 1 OS=Homo sapiens OX=9606 GN=RAVER1 PE=1 SV=1 4.56 3556.1 - 2.29E+06 - - - 1.4076 - 2.498 0.358 - 193.6 1 2 1 0.0032 22 0 0 0 1.77E+08 1.48E+08 - - - 4.7009 0.9885 221125_WJC_METTL3_EV_vs_WT_F06.23275.23275.2 0.4 14-Jul R.LTILELER[166.11].E sp|Q569K6|CC157_HUMAN 1 995.5891 0 90176 23275 2 995.587011 498.8018 Coiled-coil domain-containing protein 157 OS=Homo sapiens OX=9606 GN=CCDC157 PE=1 SV=3 4.53 3556.4 - 1.04E+06 - - - -2.0651 - 1.509 0.109 - 138.9 1 2 0 -0.0021 8 0 0 0 8.84E+04 5.09E+07 - - - 1.0863 1 221125_WJC_METTL3_EV_vs_WT_F06.23281.23281.4 1.62E-11 25/120 K.EEYITSALESTEEKLHDAASK.L "sp|P52732|KIF11_HUMAN,tr|A0A7I2YQY4|A0A7I2YQY4_HUMAN,tr|A0A7I2V3A9|A0A7I2V3A9_HUMAN,tr|A0A7I2V3V3|A0A7I2V3V3_HUMAN" 4 2350.1176 7.03 90180 23281 4 2350.113835 588.5367 Kinesin-like protein KIF11 OS=Homo sapiens OX=9606 GN=KIF11 PE=1 SV=2 4.41 3557.1 - 1.52E+06 - - - -1.6089 - 5.026 0.638 - 740.9 1 2 1 -0.0038 21 0 0 0 5.67E+08 8.06E+07 - - - 5.312 1 221125_WJC_METTL3_EV_vs_WT_F06.23286.23286.2 1.65E-12 17/46 R.NGPGFHNDIDSNSTIQEILIPASK[136.11].V sp|Q96I24|FUBP3_HUMAN 1 2574.2805 3.09 90185 23286 2 2574.272244 1288.1475 Far upstream element-binding protein 3 OS=Homo sapiens OX=9606 GN=FUBP3 PE=1 SV=2 4.54 3557.8 - 605139 - - - -3.225 - 3.436 0.755 - 288.3 1 2 0 -0.0083 24 0 0 0 6.57E+07 2.13E+07 - - - 7.6494 1 221125_WJC_METTL3_EV_vs_WT_F06.23290.23290.4 1.80E-11 34/162 K.QPIPASSMPQQIGIPTSSLTQVVHSAGR.R "sp|Q9H4A3|WNK1_HUMAN,tr|F5GWT4|F5GWT4_HUMAN,tr|A0A6Q8PFM0|A0A6Q8PFM0_HUMAN,tr|H0YH68|H0YH68_HUMAN" 4 2886.5022 2.34 90187 23290 4 2886.504251 722.6328 Serine\threonine-protein kinase WNK1 OS=Homo sapiens OX=9606 GN=WNK1 PE=1 SV=2 9.76 3558.3 - 1.35E+06 - - - 0.7189 - 4.709 0.652 - 596.7 1 2 0 0.0021 28 0 0 0 1.21E+07 5.18E+06 - - - 5.3815 0.9996 221125_WJC_METTL3_EV_vs_WT_F06.23295.23295.3 1.28E-07 15/108 R.DLGNPNTAPPTPELHGINPVFLSSNPSR.W "sp|P78364|PHC1_HUMAN,tr|J3KQH6|J3KQH6_HUMAN" 2 2940.473 1.63 90190 23295 3 2940.478912 981.1649 Polyhomeotic-like protein 1 OS=Homo sapiens OX=9606 GN=PHC1 PE=1 SV=3 5.32 3558.9 - 770586 - - - 2.016 - 2.546 0.353 - 80.1 1 2 0 0.0059 28 0 0 0 3.16E+07 1.94E+07 - - - 4.624 1 221125_WJC_METTL3_EV_vs_WT_F06.23298.23298.4 1.86E-11 24/120 K.EEYITSALESTEEK[136.11]LHDAASK[136.11].L "sp|P52732|KIF11_HUMAN,tr|A0A7I2YQY4|A0A7I2YQY4_HUMAN,tr|A0A7I2V3A9|A0A7I2V3A9_HUMAN,tr|A0A7I2V3V3|A0A7I2V3V3_HUMAN" 4 2366.146 7.03 90191 23298 4 2366.140992 592.5438 Kinesin-like protein KIF11 OS=Homo sapiens OX=9606 GN=KIF11 PE=1 SV=2 4.41 3559.3 - 3.05E+06 - - - -2.1233 - 4.507 0.613 - 491.1 1 2 1 -0.005 21 0 0 0 5.67E+08 8.06E+07 - - - 5.058 1 221125_WJC_METTL3_EV_vs_WT_F06.23299.23299.3 2.76E-07 15/84 R.DVPEDVAQEMVESGYVC[160.03]EGDHK.T "sp|Q9H4A3|WNK1_HUMAN,tr|F5GWT4|F5GWT4_HUMAN" 2 2492.0472 3.74 90192 23299 3 2492.049057 831.6897 Serine\threonine-protein kinase WNK1 OS=Homo sapiens OX=9606 GN=WNK1 PE=1 SV=2 3.95 3559.4 - 452308 - - - 0.7572 - 2.731 0.552 - 170.4 1 2 0 0.0019 22 0 0 0 4.81E+06 1.29E+06 - - - 7.0756 1 221125_WJC_METTL3_EV_vs_WT_F06.23300.23300.3 1.55E-10 20/60 R.IINEPTAAAIAYGLDR[166.11].T "sp|P0DMV8|HS71A_HUMAN,sp|P0DMV9|HS71B_HUMAN,sp|P17066|HSP76_HUMAN,tr|A0A0G2JIW1|A0A0G2JIW1_HUMAN" 4 1696.9024 0.13 90193 23300 3 1696.901377 566.6414 Heat shock 70 kDa protein 1A OS=Homo sapiens OX=9606 GN=HSPA1A PE=1 SV=1 4.37 3559.6 - 1.41E+06 - - - -0.5763 - 3.819 0.58 - 476.7 1 2 0 -0.001 16 0 0 0 2.46E+06 1.86E+07 - - - 8.4444 0.9999 221125_WJC_METTL3_EV_vs_WT_F06.23301.23301.4 3.72E-05 18/162 K.QPIPASSMPQQIGIPTSSLTQVVHSAGR[166.11].R "sp|Q9H4A3|WNK1_HUMAN,tr|F5GWT4|F5GWT4_HUMAN,tr|A0A6Q8PFM0|A0A6Q8PFM0_HUMAN,tr|H0YH68|H0YH68_HUMAN" 4 2896.5104 2.34 90194 23301 4 2896.508499 725.1349 Serine\threonine-protein kinase WNK1 OS=Homo sapiens OX=9606 GN=WNK1 PE=1 SV=2 9.76 3559.7 - 792122 - - - -0.6722 - 3.232 0.456 - 129.3 1 2 0 -0.0019 28 0 0 0 1.21E+07 5.18E+06 - - - 3.5587 1 221125_WJC_METTL3_EV_vs_WT_F06.23304.23304.3 0.00011 21/60 R.HGVQELEIELQSQLSK.K "sp|P35527|K1C9_HUMAN,tr|K7EQQ3|K7EQQ3_HUMAN" 2 1836.9581 3088.54 90195 23304 3 1836.957395 613.3267 "Keratin, type I cytoskeletal 9 OS=Homo sapiens OX=9606 GN=KRT9 PE=1 SV=3" 4.75 3560.1 - 8.88E+06 - - - -0.4067 - 3.837 0.545 - 756.1 1 2 0 -0.0007 16 0 0 0 4.42E+08 1.43E+05 - - - 8.0663 1 221125_WJC_METTL3_EV_vs_WT_F06.23305.23305.3 0.00011 33/140 R.MPEAAPPVAPAPAAPTPAAPAPAPSWPLSSSVPSQK.T "sp|P04637|P53_HUMAN,tr|J3KP33|J3KP33_HUMAN,tr|S4R334|S4R334_HUMAN,tr|A0A0U1RQC9|A0A0U1RQC9_HUMAN,tr|E7EQX7|E7EQX7_HUMAN,tr|E9PCY9|E9PCY9_HUMAN,tr|E7EMR6|E7EMR6_HUMAN" 7 3442.7595 2.74 90196 23305 3 3442.7607 1148.5938 Cellular tumor antigen p53 OS=Homo sapiens OX=9606 GN=TP53 PE=1 SV=4 5.75 3560.2 - 986702 - - - 0.3448 - 4.808 0.623 - 599.4 1 2 0 0.0012 36 0 0 0 3.80E+07 1.39E+07 - - - 9.0982 1 221125_WJC_METTL3_EV_vs_WT_F06.23306.23306.3 1.72E-14 25/124 R.GGGGSFGYSYGGGSGGGFSASSLGGGFGGGSR.G sp|P35527|K1C9_HUMAN 1 2704.1538 999 90197 23306 3 2704.148932 902.3919 "Keratin, type I cytoskeletal 9 OS=Homo sapiens OX=9606 GN=KRT9 PE=1 SV=3" 8.59 3560.4 - 1.67E+06 - - - -1.8131 - 4.315 0.691 - 336.6 1 2 0 -0.0049 32 0 0 0 1.33E+08 0.00E+00 - - - 9.6064 1 221125_WJC_METTL3_EV_vs_WT_F06.23307.23307.4 1.01E-10 14/138 R.NGPGFHNDIDSNSTIQEILIPASK[136.11].V sp|Q96I24|FUBP3_HUMAN 1 2574.2805 5.49 90198 23307 4 2574.278075 644.5774 Far upstream element-binding protein 3 OS=Homo sapiens OX=9606 GN=FUBP3 PE=1 SV=2 4.54 3560.4 - 1.42E+06 - - - -0.9599 - 2.982 0.604 - 78.3 1 2 0 -0.0025 24 0 0 0 2.29E+08 4.18E+07 - - - 4.8332 1 221125_WJC_METTL3_EV_vs_WT_F06.23309.23309.3 6.64E-07 21/140 R.MPEAAPPVAPAPAAPTPAAPAPAPSWPLSSSVPSQK[136.11].T "sp|P04637|P53_HUMAN,tr|J3KP33|J3KP33_HUMAN,tr|S4R334|S4R334_HUMAN,tr|A0A0U1RQC9|A0A0U1RQC9_HUMAN,tr|E7EQX7|E7EQX7_HUMAN,tr|E9PCY9|E9PCY9_HUMAN,tr|E7EMR6|E7EMR6_HUMAN" 7 3450.7737 2.74 90200 23309 3 3450.772502 1151.2652 Cellular tumor antigen p53 OS=Homo sapiens OX=9606 GN=TP53 PE=1 SV=4 5.75 3560.7 - 768741 - - - -0.3509 - 3.574 0.58 - 227 1 2 0 -0.0012 36 0 0 0 3.80E+07 1.39E+07 - - - 7.9364 1 221125_WJC_METTL3_EV_vs_WT_F06.23315.23315.3 3.13E-06 16/68 K.YVHYEIDAC[160.03]MDSEAPGSK[136.11].D "sp|Q86U44|MTA70_HUMAN,tr|H0YFV6|H0YFV6_HUMAN" 2 2078.8805 0.01 90204 23315 3 2078.881504 693.9674 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 4.31 3561.5 - 1.53E+06 - - - 0.4868 - 3.208 0.577 - 265.7 1 2 0 0.001 18 0 0 0 1.18E+06 1.30E+08 - - - 7.8753 1 221125_WJC_METTL3_EV_vs_WT_F06.23320.23320.3 1.97E-11 21/104 R.VHAAVQPGSLDSESGIFAC[160.03]AFDQSESR.L sp|O43660|PLRG1_HUMAN 1 2864.3035 0.88 90207 23320 3 2864.298897 955.7751 Pleiotropic regulator 1 OS=Homo sapiens OX=9606 GN=PLRG1 PE=1 SV=1 4.31 3562.2 - 2.91E+06 - - - -1.6196 - 3.733 0.712 - 346.5 1 2 0 -0.0046 27 0 0 0 8.03E+07 9.10E+07 - - - 9.5072 1 221125_WJC_METTL3_EV_vs_WT_F06.23323.23323.3 1.42E-11 19/72 K.DVHEDSITVAFENNWQPDR[166.11].Q "sp|Q06787|FMR1_HUMAN,tr|A0A087WY29|A0A087WY29_HUMAN,tr|R9WNI0|R9WNI0_HUMAN,tr|A8MQB8|A8MQB8_HUMAN,tr|A0A087WXI3|A0A087WXI3_HUMAN,tr|Q8IXW7|Q8IXW7_HUMAN,tr|G3V0J0|G3V0J0_HUMAN" 7 2281.0275 1.95 90209 23323 3 2281.02473 761.3498 Synaptic functional regulator FMR1 OS=Homo sapiens OX=9606 GN=FMR1 PE=1 SV=1 4.1 3562.5 - 1.99E+06 - - - -1.2183 - 3.744 0.702 - 428.7 1 2 0 -0.0028 19 0 0 0 8.73E+07 4.47E+07 - - - 9.6092 1 221125_WJC_METTL3_EV_vs_WT_F06.23324.23324.2 1.99E-08 26/30 R.HGVQELEIELQSQLSK.K "sp|P35527|K1C9_HUMAN,tr|K7EQQ3|K7EQQ3_HUMAN" 2 1836.9581 999 90210 23324 2 1836.959717 919.4863 "Keratin, type I cytoskeletal 9 OS=Homo sapiens OX=9606 GN=KRT9 PE=1 SV=3" 4.75 3562.6 - 1.21E+06 - - - 0.8574 - 5.299 0.729 - 3102.2 1 2 0 0.0016 16 0 0 0 2.99E+07 0.00E+00 - - - 8.5246 1 221125_WJC_METTL3_EV_vs_WT_F06.23327.23327.2 3.14E-07 16/30 R.R[166.11]AEQDSTTVAAFASSL.V "sp|Q86U44|MTA70_HUMAN,tr|F5H6D8|F5H6D8_HUMAN,tr|H0YFV6|H0YFV6_HUMAN,tr|B4DTN4|B4DTN4_HUMAN" 4 1662.8088 0 90211 23327 2 1662.807253 832.4117 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 4.37 3563 - 1.80E+06 - - - -0.9598 - 2.73 0.59 - 522.1 1 1 0 -0.0016 16 0 0 0 1.86E+05 7.67E+07 - - - 5.8674 1 221125_WJC_METTL3_EV_vs_WT_F06.23328.23328.3 2.05E-08 18/84 R.AQTEGINISEEALNHLGEIGTK.T "sp|Q9Y265|RUVB1_HUMAN,tr|H7C4G5|H7C4G5_HUMAN,tr|J3QLR1|J3QLR1_HUMAN" 3 2323.1656 0.67 90212 23328 3 2323.154183 775.3958 RuvB-like 1 OS=Homo sapiens OX=9606 GN=RUVBL1 PE=1 SV=1 4.48 3563.1 - 875648 - - - -4.9011 - 4.438 0.632 - 333.9 1 2 0 -0.0114 22 0 0 0 4.02E+07 5.99E+07 - - - 9.116 1 221125_WJC_METTL3_EV_vs_WT_F06.23329.23329.4 8.40E-12 30/150 K.RGDQIIAVNGQSLEGVTHEEAVAILK.R "sp|O75970|MPDZ_HUMAN,tr|B7ZB24|B7ZB24_HUMAN,tr|H0YGQ3|H0YGQ3_HUMAN,tr|F5H1U9|F5H1U9_HUMAN,tr|A0A075B6R8|A0A075B6R8_HUMAN" 5 2746.4614 3.55 90213 23329 4 2746.457411 687.6226 Multiple PDZ domain protein OS=Homo sapiens OX=9606 GN=MPDZ PE=1 SV=2 4.83 3563.2 - 1.08E+06 - - - -1.4368 - 4.514 0.684 - 583.6 1 2 0 -0.0039 26 0 0 0 1.73E+07 4.88E+06 - - - 5.6539 0.9999 221125_WJC_METTL3_EV_vs_WT_F06.23330.23330.2 4.34E-08 30-Dec K.SYELPDGQVITIGNER.F "sp|Q6S8J3|POTEE_HUMAN,sp|P63261|ACTG_HUMAN,sp|P68133|ACTS_HUMAN,sp|P62736|ACTA_HUMAN,sp|Q9BYX7|ACTBM_HUMAN,sp|P68032|ACTC_HUMAN,sp|Q562R1|ACTBL_HUMAN,sp|P60709|ACTB_HUMAN,sp|P63267|ACTH_HUMAN,sp|A5A3E0|POTEF_HUMAN,tr|A0A804GS07|A0A804GS07_HUMAN,tr|E7EVS6|E7EVS6_HUMAN,tr|A0A6Q8PFE4|A0A6Q8PFE4_HUMAN,tr|A0A2R8YEA7|A0A2R8YEA7_HUMAN,tr|A0A804HKV3|A0A804HKV3_HUMAN,tr|A0A2R8Y793|A0A2R8Y793_HUMAN,tr|I3L4N8|I3L4N8_HUMAN,tr|A6NL76|A6NL76_HUMAN" 18 1789.8846 5.95 90214 23330 2 1789.885925 895.9496 POTE ankyrin domain family member E OS=Homo sapiens OX=9606 GN=POTEE PE=2 SV=3 4.14 3563.4 - 515931 - - - 0.7162 - 2.433 0.578 - 366.4 1 2 0 0.0013 16 0 0 0 1.96E+07 3.29E+06 - - - 5.4957 0.9961 221125_WJC_METTL3_EV_vs_WT_F06.23335.23335.3 0.000442 16/52 K.LLHHLSDLALTLPT.D "sp|Q86U44|MTA70_HUMAN,tr|B4E349|B4E349_HUMAN,tr|F5H6D8|F5H6D8_HUMAN,tr|H0YFV6|H0YFV6_HUMAN,tr|B4DTN4|B4DTN4_HUMAN" 5 1542.877 - 90216 23335 3 1542.875721 515.2996 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 5.97 3564 - 1.74E+06 - - - -0.8154 - 3.169 0.417 - 237.6 1 1 0 -0.0013 14 0 0 0 - - - - - 6.254 1 221125_WJC_METTL3_EV_vs_WT_F06.23339.23339.3 5.00E-16 28/104 R.VHAAVQPGSLDSESGIFAC[160.03]AFDQSESR[166.11].L sp|O43660|PLRG1_HUMAN 1 2874.3118 0.88 90218 23339 3 2874.305547 959.1112 Pleiotropic regulator 1 OS=Homo sapiens OX=9606 GN=PLRG1 PE=1 SV=1 4.31 3564.4 - 4.18E+06 - - - -2.1776 - 5.168 0.781 - 728 1 2 0 -0.0063 27 0 0 0 8.03E+07 9.10E+07 - - - 11.0244 1 221125_WJC_METTL3_EV_vs_WT_F06.23345.23345.4 3.69E-09 28/174 K.SPQPPVEEEDEHFDDTVVC[160.03]LDTYNC[160.03]DLHFK.L "sp|Q00839|HNRPU_HUMAN,tr|Q5RI18|Q5RI18_HUMAN,tr|A0A1W2PP35|A0A1W2PP35_HUMAN,tr|A0A1W2PPS1|A0A1W2PPS1_HUMAN,tr|A0A1W2PRI6|A0A1W2PRI6_HUMAN" 5 3634.5504 1.07 90222 23345 4 3634.545238 909.6449 Heterogeneous nuclear ribonucleoprotein U OS=Homo sapiens OX=9606 GN=HNRNPU PE=1 SV=6 3.97 3565.1 - 2.81E+06 - - - -1.4326 - 4.422 0.652 - 451.3 1 2 0 -0.0052 30 0 0 0 1.86E+08 1.74E+08 - - - 5.3545 1 221125_WJC_METTL3_EV_vs_WT_F06.23356.23356.3 4.87E-17 21/92 R.NGPGFHNDIDSNSTIQEILIPASK.V sp|Q96I24|FUBP3_HUMAN 1 2566.2663 2.04 90227 23356 3 2566.264622 856.4294 Far upstream element-binding protein 3 OS=Homo sapiens OX=9606 GN=FUBP3 PE=1 SV=2 4.54 3566.6 - 3.76E+07 - - - -0.6718 - 4.366 0.779 - 220.7 1 2 0 -0.0017 24 0 0 0 5.61E+09 2.75E+09 - - - 10.6478 1 221125_WJC_METTL3_EV_vs_WT_F06.23357.23357.3 7.24E-10 20/92 R.NGPGFHNDIDSNSTIQEILIPASK[136.11].V sp|Q96I24|FUBP3_HUMAN 1 2574.2805 2.04 90228 23357 3 2574.276973 859.1008 Far upstream element-binding protein 3 OS=Homo sapiens OX=9606 GN=FUBP3 PE=1 SV=2 4.54 3566.7 - 1.70E+07 - - - -1.388 - 3.991 0.694 - 214.5 1 2 0 -0.0036 24 0 0 0 5.61E+09 2.75E+09 - - - 9.491 1 221125_WJC_METTL3_EV_vs_WT_F06.23365.23365.4 3.61E-09 31/132 K.GADSLEDFLYHEGYAC[160.03]TSIHGDR.S "sp|O00571|DDX3X_HUMAN,sp|O15523|DDX3Y_HUMAN,tr|A0A2R8YFR4|A0A2R8YFR4_HUMAN,tr|A0A2R8YCW1|A0A2R8YCW1_HUMAN,tr|A0A2R8YDH3|A0A2R8YDH3_HUMAN,tr|A0A2R8YDT5|A0A2R8YDT5_HUMAN,tr|A0A2R8Y645|A0A2R8Y645_HUMAN,tr|A0A2R8YF78|A0A2R8YF78_HUMAN,tr|A0A0D9SFB3|A0A0D9SFB3_HUMAN,tr|A0A2R8YFS5|A0A2R8YFS5_HUMAN,tr|A0A0D9SF53|A0A0D9SF53_HUMAN,tr|A0A0J9YVQ7|A0A0J9YVQ7_HUMAN,tr|A0A2R8Y5G6|A0A2R8Y5G6_HUMAN,tr|A0A2R8Y7T2|A0A2R8Y7T2_HUMAN,tr|A0A0D9SG12|A0A0D9SG12_HUMAN,tr|F6S8Q4|F6S8Q4_HUMAN,tr|A0A2U3TZJ9|A0A2U3TZJ9_HUMAN,tr|A0A2R8Y4A4|A0A2R8Y4A4_HUMAN" 18 2612.1238 1.55 90232 23365 4 2612.123703 654.0382 ATP-dependent RNA helicase DDX3X OS=Homo sapiens OX=9606 GN=DDX3X PE=1 SV=3 4.42 3567.6 - 1.94E+06 - - - -0.0299 - 4.702 0.668 - 883.1 1 2 0 -0.0001 23 0 0 0 5.79E+07 3.73E+07 - - - 5.5418 1 221125_WJC_METTL3_EV_vs_WT_F06.23366.23366.3 2.16E-06 22/144 R.GAGFNQNNGAGSENFGLGVVPVSASPSSVEVHPVLEK[136.11].L "sp|Q7Z739|YTHD3_HUMAN,tr|A0A087X0Q1|A0A087X0Q1_HUMAN,tr|A0A024R7W5|A0A024R7W5_HUMAN,tr|A0A087WY31|A0A087WY31_HUMAN" 4 3658.8107 1.57 90233 23366 3 3659.807975 1220.6108 YTH domain-containing family protein 3 OS=Homo sapiens OX=9606 GN=YTHDF3 PE=1 SV=1 4.75 3567.8 - 721344 - - - 272.567 - 4.054 0.656 - 237.9 1 2 0 0.9973 37 0 0 0 1.66E+08 1.06E+08 - - - 8.7977 1 221125_WJC_METTL3_EV_vs_WT_F06.23367.23367.3 2.21E-13 28/144 R.GAGFNQNNGAGSENFGLGVVPVSASPSSVEVHPVLEK.L "sp|Q7Z739|YTHD3_HUMAN,tr|A0A087X0Q1|A0A087X0Q1_HUMAN,tr|A0A024R7W5|A0A024R7W5_HUMAN,tr|A0A087WY31|A0A087WY31_HUMAN" 4 3650.7965 1.57 90234 23367 3 3650.797413 1217.9394 YTH domain-containing family protein 3 OS=Homo sapiens OX=9606 GN=YTHDF3 PE=1 SV=1 4.75 3567.9 - 1.22E+06 - - - 0.249 - 4.763 0.778 - 358.4 1 2 0 0.0009 37 0 0 0 1.66E+08 1.06E+08 - - - 10.8047 0.9999 221125_WJC_METTL3_EV_vs_WT_F06.23376.23376.4 0.00103 17/114 R.TLHEWLQQHGIPGLQGVDTR[166.11].E "sp|P27708|PYR1_HUMAN,tr|F8VPD4|F8VPD4_HUMAN" 2 2294.1795 0.35 90238 23376 4 2294.175857 574.5522 CAD protein OS=Homo sapiens OX=9606 GN=CAD PE=1 SV=3 5.92 3569.1 - 896215 - - - -1.6023 - 2.978 0.41 - 158.2 1 2 0 -0.0037 20 0 0 0 1.26E+07 3.58E+07 - - - 3.1584 1 221125_WJC_METTL3_EV_vs_WT_F06.23378.23378.4 1.10E-14 41/216 R.GAGFNQNNGAGSENFGLGVVPVSASPSSVEVHPVLEK.L "sp|Q7Z739|YTHD3_HUMAN,tr|A0A087X0Q1|A0A087X0Q1_HUMAN,tr|A0A024R7W5|A0A024R7W5_HUMAN,tr|A0A087WY31|A0A087WY31_HUMAN" 4 3650.7965 1.47 90239 23378 4 3650.792773 913.7064 YTH domain-containing family protein 3 OS=Homo sapiens OX=9606 GN=YTHDF3 PE=1 SV=1 4.75 3569.3 - 5.14E+06 - - - -1.022 - 5.458 0.729 - 622 1 2 0 -0.0037 37 0 0 0 2.05E+08 1.40E+08 - - - 6.0677 1 221125_WJC_METTL3_EV_vs_WT_F06.23382.23382.3 1.08E-08 21/88 K.GADSLEDFLYHEGYAC[160.03]TSIHGDR.S "sp|O00571|DDX3X_HUMAN,sp|O15523|DDX3Y_HUMAN,tr|A0A2R8YFR4|A0A2R8YFR4_HUMAN,tr|A0A2R8YCW1|A0A2R8YCW1_HUMAN,tr|A0A2R8YDH3|A0A2R8YDH3_HUMAN,tr|A0A2R8YDT5|A0A2R8YDT5_HUMAN,tr|A0A2R8Y645|A0A2R8Y645_HUMAN,tr|A0A2R8YF78|A0A2R8YF78_HUMAN,tr|A0A0D9SFB3|A0A0D9SFB3_HUMAN,tr|A0A2R8YFS5|A0A2R8YFS5_HUMAN,tr|A0A0D9SF53|A0A0D9SF53_HUMAN,tr|A0A0J9YVQ7|A0A0J9YVQ7_HUMAN,tr|A0A2R8Y5G6|A0A2R8Y5G6_HUMAN,tr|A0A2R8Y7T2|A0A2R8Y7T2_HUMAN,tr|A0A0D9SG12|A0A0D9SG12_HUMAN,tr|F6S8Q4|F6S8Q4_HUMAN,tr|A0A2U3TZJ9|A0A2U3TZJ9_HUMAN,tr|A0A2R8Y4A4|A0A2R8Y4A4_HUMAN" 18 2612.1238 1.16 90242 23382 3 2612.126738 871.7152 ATP-dependent RNA helicase DDX3X OS=Homo sapiens OX=9606 GN=DDX3X PE=1 SV=3 4.42 3569.8 - 730168 - - - 1.132 - 3.975 0.671 - 448.7 1 2 0 0.003 23 0 0 0 7.44E+06 6.40E+06 - - - 9.2576 1 221125_WJC_METTL3_EV_vs_WT_F06.23387.23387.4 2.12E-11 24/120 K.YRPQTLNDLISHQDILSTIQK.F "sp|P40937|RFC5_HUMAN,tr|F5H0U6|F5H0U6_HUMAN,tr|C9JH72|C9JH72_HUMAN,tr|F5H304|F5H304_HUMAN" 4 2482.318 0.96 90244 23387 4 2482.31627 621.5868 Replication factor C subunit 5 OS=Homo sapiens OX=9606 GN=RFC5 PE=1 SV=1 6.75 3570.5 - 1.25E+06 - - - -0.6917 - 4.597 0.601 - 478.2 1 2 0 -0.0017 21 0 0 0 3.06E+07 3.20E+07 - - - 4.961 0.9999 221125_WJC_METTL3_EV_vs_WT_F06.23388.23388.4 2.92E-06 15/114 R.TLHEWLQQHGIPGLQGVDTR.E "sp|P27708|PYR1_HUMAN,tr|F8VPD4|F8VPD4_HUMAN" 2 2284.1713 0.34 90245 23388 4 2284.168893 572.0501 CAD protein OS=Homo sapiens OX=9606 GN=CAD PE=1 SV=3 5.92 3570.6 - 914803 - - - -1.0376 - 2.81 0.407 - 146.3 1 2 0 -0.0024 20 0 0 0 1.26E+07 3.67E+07 - - - 3.1133 0.8366 221125_WJC_METTL3_EV_vs_WT_F06.23390.23390.3 0.000964 Dec-68 K.R[166.11]R[166.11]AEQDSTTVAAFASSLV.S "sp|Q86U44|MTA70_HUMAN,tr|F5H6D8|F5H6D8_HUMAN,tr|H0YFV6|H0YFV6_HUMAN,tr|B4DTN4|B4DTN4_HUMAN" 4 1927.9866 0.001 90247 23390 3 1927.983712 643.6695 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 6.07 3570.7 - 3.83E+06 - - - -1.5208 - 1.953 0.359 - 128.6 1 1 1 -0.0029 18 0 0 0 0.00E+00 9.46E+07 - - - 4.2085 1 221125_WJC_METTL3_EV_vs_WT_F06.23395.23395.4 1.19E-13 28/120 K.YR[166.11]PQTLNDLISHQDILSTIQK[136.11].F "sp|P40937|RFC5_HUMAN,tr|F5H0U6|F5H0U6_HUMAN,tr|C9JH72|C9JH72_HUMAN,tr|F5H304|F5H304_HUMAN" 4 2500.3405 0.96 90250 23395 4 2500.337269 626.0924 Replication factor C subunit 5 OS=Homo sapiens OX=9606 GN=RFC5 PE=1 SV=1 6.75 3571.4 - 1.12E+06 - - - -1.275 - 5.233 0.594 - 738.7 1 2 0 -0.0032 21 0 0 0 3.06E+07 3.20E+07 - - - 4.9425 1 221125_WJC_METTL3_EV_vs_WT_F06.23400.23400.4 1.24E-14 40/198 K.AQHTLPQDPAIVQSSLGSASASPFQPHVPYSPFR.G "sp|Q9BX40|LS14B_HUMAN,tr|Q5TBQ1|Q5TBQ1_HUMAN,tr|A0A0C4DFV2|A0A0C4DFV2_HUMAN" 3 3616.8063 1.11 90253 23400 4 3616.802375 905.2088 Protein LSM14 homolog B OS=Homo sapiens OX=9606 GN=LSM14B PE=1 SV=1 6.96 3572 - 2.60E+06 - - - -1.0797 - 5.611 0.61 - 789.9 1 2 0 -0.0039 34 0 0 0 1.29E+08 1.16E+08 - - - 5.0487 1 221125_WJC_METTL3_EV_vs_WT_F06.23401.23401.4 7.31E-12 22/108 K.NTHATTHNAYDLEVIDIFK[136.11].L "sp|P09874|PARP1_HUMAN,tr|A0A7I2V3E1|A0A7I2V3E1_HUMAN" 2 2209.0895 1.07 90254 23401 4 2209.086284 553.2797 Poly [ADP-ribose] polymerase 1 OS=Homo sapiens OX=9606 GN=PARP1 PE=1 SV=4 5.21 3572.1 - 2.32E+06 - - - -1.4544 - 3.634 0.635 - 380.5 1 2 0 -0.0032 19 0 0 0 3.32E+08 3.12E+08 - - - 5.1886 1 221125_WJC_METTL3_EV_vs_WT_F06.23402.23402.4 5.16E-06 14/120 K.SYSMIVNNLLK[136.11]PISVEGSSK[136.11]K[136.11].V sp|Q9HB71|CYBP_HUMAN 1 2317.2778 0.31 90255 23402 4 2317.274344 580.3267 Calcyclin-binding protein OS=Homo sapiens OX=9606 GN=CACYBP PE=1 SV=2 9.52 3572.2 - 635892 - - - -1.478 - 2.64 0.522 - 71.3 1 2 0 -0.0034 21 0 0 0 4.81E+06 1.57E+07 - - - 4.0895 1 221125_WJC_METTL3_EV_vs_WT_F06.23405.23405.3 1.61E-15 23/72 K.NTHATTHNAYDLEVIDIFK.L "sp|P09874|PARP1_HUMAN,tr|A0A7I2V3E1|A0A7I2V3E1_HUMAN" 2 2201.0753 0.99 90256 23405 3 2201.079446 734.699 Poly [ADP-ribose] polymerase 1 OS=Homo sapiens OX=9606 GN=PARP1 PE=1 SV=4 5.21 3572.6 - 1.26E+06 - - - 1.885 - 4.299 0.681 - 947.9 1 2 0 0.0041 19 0 0 0 1.84E+08 1.87E+08 - - - 9.7143 1 221125_WJC_METTL3_EV_vs_WT_F06.23409.23409.3 8.65E-12 14/96 R.SAIPEQIISSTLSSPSSNAPDPC[160.03]AK.E "sp|Q96HA1|P121A_HUMAN,sp|A8CG34|P121C_HUMAN,sp|Q6PJE2|POZP3_HUMAN,tr|A0A0J9YWR1|A0A0J9YWR1_HUMAN,tr|C9J370|C9J370_HUMAN,tr|C9JER0|C9JER0_HUMAN" 6 2556.2377 0.22 90259 23409 3 2556.239622 853.0865 Nuclear envelope pore membrane protein POM 121 OS=Homo sapiens OX=9606 GN=POM121 PE=1 SV=2 4.37 3573.1 - 3.68E+06 - - - 0.7331 - 2.933 0.676 - 107.9 1 2 0 0.0019 25 0 0 0 1.69E+08 7.52E+08 - - - 8.5518 1 221125_WJC_METTL3_EV_vs_WT_F06.23410.23410.4 6.69E-13 22/108 K.NTHATTHNAYDLEVIDIFK.L "sp|P09874|PARP1_HUMAN,tr|A0A7I2V3E1|A0A7I2V3E1_HUMAN" 2 2201.0753 1.06 90260 23410 4 2201.075314 551.2761 Poly [ADP-ribose] polymerase 1 OS=Homo sapiens OX=9606 GN=PARP1 PE=1 SV=4 5.21 3573.1 - 2.94E+06 - - - 0.0077 - 3.343 0.679 - 367.1 1 2 0 0 19 0 0 0 3.32E+08 3.12E+08 - - - 5.5443 1 221125_WJC_METTL3_EV_vs_WT_F06.23411.23411.4 2.20E-06 16/108 R.GLLQDDAHPTLVTYADHSK[136.11].L "sp|Q86U44|MTA70_HUMAN,tr|F5H6D8|F5H6D8_HUMAN,tr|H0YFV6|H0YFV6_HUMAN,tr|B4DTN4|B4DTN4_HUMAN" 4 2088.0367 0 90261 23411 4 2088.034342 523.0165 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 5.13 3573.3 - 825056 - - - -1.1451 - 2.972 0.52 - 258.1 1 2 0 -0.0024 19 0 0 0 3.29E+05 8.50E+07 - - - 4.1199 1 221125_WJC_METTL3_EV_vs_WT_F06.23412.23412.3 2.26E-06 Oct-76 R.TLHEWLQQHGIPGLQGVDTR.E "sp|P27708|PYR1_HUMAN,tr|F8VPD4|F8VPD4_HUMAN" 2 2284.1713 0.15 90262 23412 3 2284.168069 762.3977 CAD protein OS=Homo sapiens OX=9606 GN=CAD PE=1 SV=3 5.92 3573.4 - 575848 - - - -1.3983 - 2.594 0.478 - 65.2 1 2 0 -0.0032 20 0 0 0 8.94E+06 6.03E+07 - - - 6.1808 1 221125_WJC_METTL3_EV_vs_WT_F06.23416.23416.3 5.14E-11 28/72 K.NTHATTHNAYDLEVIDIFK[136.11].L "sp|P09874|PARP1_HUMAN,tr|A0A7I2V3E1|A0A7I2V3E1_HUMAN" 2 2209.0895 1 90264 23416 3 2209.087593 737.3704 Poly [ADP-ribose] polymerase 1 OS=Homo sapiens OX=9606 GN=PARP1 PE=1 SV=4 5.21 3573.9 - 2.56E+06 - - - -0.8619 - 4.875 0.696 - 1495.3 1 2 0 -0.0019 19 0 0 0 1.84E+08 1.84E+08 - - - 10.1911 1 221125_WJC_METTL3_EV_vs_WT_F06.23417.23417.3 5.89E-14 23/108 K.SK[136.11]GGNVGYGEPSDQADVVMSMTTDDFVK[136.11].M sp|Q6YN16|HSDL2_HUMAN 1 2949.3343 0.2 90265 23417 3 2949.327716 984.1187 Hydroxysteroid dehydrogenase-like protein 2 OS=Homo sapiens OX=9606 GN=HSDL2 PE=1 SV=1 4.04 3574.1 - 541773 - - - -2.2337 - 4.432 0.745 - 584.5 1 2 1 -0.0066 28 0 0 0 3.52E+06 1.77E+07 - - - 10.2695 1 221125_WJC_METTL3_EV_vs_WT_F06.23420.23420.4 9.71E-10 18/132 R.KNNFSDTGNFGFGIQEHIDLGIK.Y "sp|P62913|RL11_HUMAN,tr|Q5VVC8|Q5VVC8_HUMAN" 2 2550.2503 0.88 90267 23420 4 2550.249262 638.5699 60S ribosomal protein L11 OS=Homo sapiens OX=9606 GN=RPL11 PE=1 SV=2 5.38 3574.4 - 885669 - - - -0.4078 - 3.64 0.62 - 272.9 1 2 0 -0.001 23 0 0 0 3.66E+08 4.14E+08 - - - 5.0408 1 221125_WJC_METTL3_EV_vs_WT_F06.23422.23422.4 1.71E-09 47/198 K.AQHTLPQDPAIVQSSLGSASASPFQPHVPYSPFR[166.11].G "sp|Q9BX40|LS14B_HUMAN,tr|Q5TBQ1|Q5TBQ1_HUMAN,tr|A0A0C4DFV2|A0A0C4DFV2_HUMAN" 3 3626.8146 1.11 90268 23422 4 3626.813395 907.7109 Protein LSM14 homolog B OS=Homo sapiens OX=9606 GN=LSM14B PE=1 SV=1 6.96 3574.6 - 5.22E+06 - - - -0.3185 - 5.99 0.666 - 908.5 1 2 0 -0.0012 34 0 0 0 1.28E+08 1.16E+08 - - - 5.5564 0.9998 221125_WJC_METTL3_EV_vs_WT_F06.23425.23425.3 6.99E-06 Nov-68 K.LVINGNPITIFQER[166.11]DPSK[136.11].L sp|P04406|G3P_HUMAN 1 2058.1229 1.11 90271 23425 3 2058.125439 687.0482 Glyceraldehyde-3-phosphate dehydrogenase OS=Homo sapiens OX=9606 GN=GAPDH PE=1 SV=3 6.07 3575 - 400075 - - - 1.2531 - 2.5 0.48 - 87.2 1 2 1 0.0026 18 0 0 0 9.09E+07 8.20E+07 - - - 6.1725 0.9999 221125_WJC_METTL3_EV_vs_WT_F06.23431.23431.4 4.95E-05 15/132 R.QGSFTIEK[136.11]PSPNIPIELIPHINK[136.11].Q "sp|Q5SW79|CE170_HUMAN,tr|H0Y2V6|H0Y2V6_HUMAN" 2 2587.4345 1.95 90275 23431 4 2587.436737 647.8659 Centrosomal protein of 170 kDa OS=Homo sapiens OX=9606 GN=CEP170 PE=1 SV=1 6.76 3575.8 - 717725 - - - 0.8746 - 2.353 0.432 - 105.8 1 2 0 0.0023 23 0 0 0 3.63E+07 1.86E+07 - - - 3.2627 1 221125_WJC_METTL3_EV_vs_WT_F06.23435.23435.4 1.00E-10 27/162 R.SIYVGNVDYGATAEELEAHFHGC[160.03]GSVNR.V "sp|Q86U42|PABP2_HUMAN,tr|B4DEH8|B4DEH8_HUMAN,tr|G3V4T2|G3V4T2_HUMAN,tr|A0A7I2V383|A0A7I2V383_HUMAN" 4 3051.3781 1.1 90277 23435 4 3051.378969 763.8518 Polyadenylate-binding protein 2 OS=Homo sapiens OX=9606 GN=PABPN1 PE=1 SV=3 4.8 3576.3 - 2.92E+06 - - - 0.2854 - 5.016 0.664 - 475.3 1 2 0 0.0009 28 0 0 0 1.13E+08 1.03E+08 - - - 5.5059 1 221125_WJC_METTL3_EV_vs_WT_F06.23437.23437.4 3.52E-07 26/216 K.TVGTALSSSGMTSIATNSVPPVSSAAPKPTSWAAIAR.K "sp|Q7Z739|YTHD3_HUMAN,tr|A0A087X0Q1|A0A087X0Q1_HUMAN,tr|A0A024R7W5|A0A024R7W5_HUMAN,tr|A0A087WY31|A0A087WY31_HUMAN" 4 3570.8352 1.25 90279 23437 4 3570.840342 893.7161 YTH domain-containing family protein 3 OS=Homo sapiens OX=9606 GN=YTHDF3 PE=1 SV=1 11 3576.5 - 1.29E+06 - - - 1.4408 - 4.035 0.595 - 108.7 1 2 0 0.0051 37 0 0 0 2.34E+07 1.88E+07 - - - 4.8124 1 221125_WJC_METTL3_EV_vs_WT_F06.23445.23445.3 4.93E-07 21/56 R.RHEILQWVLQTDSQQ.- sp|Q96AG4|LRC59_HUMAN 1 1879.9541 1.21 90285 23445 3 1879.957672 627.6586 Leucine-rich repeat-containing protein 59 OS=Homo sapiens OX=9606 GN=LRRC59 PE=1 SV=1 5.32 3577.6 - 2.46E+06 - - - 1.9213 - 3.343 0.556 - 785.2 1 2 0 0.0036 15 0 0 0 8.75E+07 7.23E+07 - - - 7.887 1 221125_WJC_METTL3_EV_vs_WT_F06.23447.23447.4 5.05E-12 32/162 R.SIYVGNVDYGATAEELEAHFHGC[160.03]GSVNR[166.11].V "sp|Q86U42|PABP2_HUMAN,tr|B4DEH8|B4DEH8_HUMAN,tr|G3V4T2|G3V4T2_HUMAN,tr|A0A7I2V383|A0A7I2V383_HUMAN" 4 3061.3864 1.1 90286 23447 4 3061.387722 766.3539 Polyadenylate-binding protein 2 OS=Homo sapiens OX=9606 GN=PABPN1 PE=1 SV=3 4.8 3577.8 - 8.30E+06 - - - 0.4423 - 5.376 0.605 - 875.2 1 2 0 0.0014 28 0 0 0 1.13E+08 1.03E+08 - - - 5.0138 1 221125_WJC_METTL3_EV_vs_WT_F06.23448.23448.4 2.95E-08 30/216 K.TVGTALSSSGMTSIATNSVPPVSSAAPK[136.11]PTSWAAIAR[166.11].K "sp|Q7Z739|YTHD3_HUMAN,tr|A0A087X0Q1|A0A087X0Q1_HUMAN,tr|A0A024R7W5|A0A024R7W5_HUMAN,tr|A0A087WY31|A0A087WY31_HUMAN" 4 3588.8577 1.25 90287 23448 4 3588.859513 898.2217 YTH domain-containing family protein 3 OS=Homo sapiens OX=9606 GN=YTHDF3 PE=1 SV=1 11 3577.9 - 1.30E+06 - - - 0.5144 - 4.024 0.575 - 155.4 1 2 0 0.0018 37 0 0 0 2.34E+07 1.88E+07 - - - 4.6385 1 221125_WJC_METTL3_EV_vs_WT_F06.23449.23449.3 3.15E-16 35/144 K.TVGTALSSSGMTSIATNSVPPVSSAAPKPTSWAAIAR.K "sp|Q7Z739|YTHD3_HUMAN,tr|A0A087X0Q1|A0A087X0Q1_HUMAN,tr|A0A024R7W5|A0A024R7W5_HUMAN,tr|A0A087WY31|A0A087WY31_HUMAN" 4 3570.8352 1.68 90288 23449 3 3570.844181 1191.2857 YTH domain-containing family protein 3 OS=Homo sapiens OX=9606 GN=YTHDF3 PE=1 SV=1 11 3578 - 979554 - - - 2.5159 - 4.783 0.704 - 452.1 1 2 0 0.009 37 0 0 0 1.36E+07 8.11E+06 - - - 9.9871 1 221125_WJC_METTL3_EV_vs_WT_F06.23452.23452.3 2.72E-10 20/68 K.LVINGNPITIFQERDPSK.L sp|P04406|G3P_HUMAN 1 2040.1004 1.11 90289 23452 3 2040.09807 681.0407 Glyceraldehyde-3-phosphate dehydrogenase OS=Homo sapiens OX=9606 GN=GAPDH PE=1 SV=3 6.07 3578.4 - 1.68E+06 - - - -1.1372 - 3.589 0.616 - 450.3 1 2 1 -0.0023 18 0 0 0 9.09E+07 8.18E+07 - - - 8.5892 0.9997 221125_WJC_METTL3_EV_vs_WT_F06.23453.23453.4 0.000285 15/132 R.QGSFTIEKPSPNIPIELIPHINK.Q "sp|Q5SW79|CE170_HUMAN,tr|H0Y2V6|H0Y2V6_HUMAN" 2 2571.4061 1.26 90290 23453 4 2571.409357 643.8588 Centrosomal protein of 170 kDa OS=Homo sapiens OX=9606 GN=CEP170 PE=1 SV=1 6.76 3578.6 - 1.45E+06 - - - 1.2767 - 2.393 0.367 - 55.5 1 2 0 0.0033 23 0 0 0 2.03E+07 1.62E+07 - - - 2.7022 1 221125_WJC_METTL3_EV_vs_WT_F06.23454.23454.3 2.11E-09 19/140 A.VGVAGSSLTSFGTETSNSGTLPQSSAVGSAFTQDTR[166.11].S "sp|Q8ND56|LS14A_HUMAN,tr|A0A140TA76|A0A140TA76_HUMAN,tr|K7EMZ9|K7EMZ9_HUMAN" 3 3513.6735 0.88 90291 23454 3 3513.678319 1172.2318 Protein LSM14 homolog A OS=Homo sapiens OX=9606 GN=LSM14A PE=1 SV=3 4.37 3578.7 - 981644 - - - 1.3758 - 3.751 0.641 - 239.4 1 1 0 0.0048 36 0 0 0 1.59E+07 1.80E+07 - - - 8.7267 1 221125_WJC_METTL3_EV_vs_WT_F06.23455.23455.3 0.000134 22/144 K.TVGTALSSSGMTSIATNSVPPVSSAAPK[136.11]PTSWAAIAR[166.11].K "sp|Q7Z739|YTHD3_HUMAN,tr|A0A087X0Q1|A0A087X0Q1_HUMAN,tr|A0A024R7W5|A0A024R7W5_HUMAN,tr|A0A087WY31|A0A087WY31_HUMAN" 4 3588.8577 1.68 90292 23455 3 3588.851713 1197.2932 YTH domain-containing family protein 3 OS=Homo sapiens OX=9606 GN=YTHDF3 PE=1 SV=1 11 3578.8 - 708539 - - - -1.659 - 3.588 0.586 - 131.8 1 2 0 -0.006 37 0 0 0 1.36E+07 8.11E+06 - - - 8.011 1 221125_WJC_METTL3_EV_vs_WT_F06.23463.23463.3 3.08E-05 17/56 R.R[166.11]HEILQWVLQTDSQQ.- sp|Q96AG4|LRC59_HUMAN 1 1889.9623 1.21 90298 23463 3 1889.964252 630.9947 Leucine-rich repeat-containing protein 59 OS=Homo sapiens OX=9606 GN=LRRC59 PE=1 SV=1 5.32 3579.8 - 2.45E+06 - - - 1.017 - 3.193 0.509 - 454.6 1 2 0 0.0019 15 0 0 0 8.75E+07 7.23E+07 - - - 7.2437 1 221125_WJC_METTL3_EV_vs_WT_F06.23464.23464.3 1.01E-17 30/108 R.SIYVGNVDYGATAEELEAHFHGC[160.03]GSVNR.V "sp|Q86U42|PABP2_HUMAN,tr|B4DEH8|B4DEH8_HUMAN,tr|G3V4T2|G3V4T2_HUMAN,tr|A0A7I2V383|A0A7I2V383_HUMAN" 4 3051.3781 1.07 90299 23464 3 3051.376633 1018.1333 Polyadenylate-binding protein 2 OS=Homo sapiens OX=9606 GN=PABPN1 PE=1 SV=3 4.8 3579.9 - 1.02E+06 - - - -0.4801 - 5.515 0.715 - 942.3 1 2 0 -0.0015 28 0 0 0 9.53E+06 8.91E+06 - - - 10.4394 0.9998 221125_WJC_METTL3_EV_vs_WT_F06.23470.23470.4 9.78E-07 24/102 K.VTMQNLNDRLASYLDKVR.A "sp|P13645|K1C10_HUMAN,sp|P02533|K1C14_HUMAN,sp|P08779|K1C16_HUMAN,tr|A0A1B0GVI3|A0A1B0GVI3_HUMAN" 4 2135.1157 68.16 90303 23470 4 2135.115733 534.7862 "Keratin, type I cytoskeletal 10 OS=Homo sapiens OX=9606 GN=KRT10 PE=1 SV=6" 8.56 3580.7 - 775463 - - - 0.0052 - 3.41 0.466 - 591.5 1 2 2 0 18 0 0 0 1.08E+07 1.58E+05 - - - 3.7023 0.9992 221125_WJC_METTL3_EV_vs_WT_F06.23472.23472.4 1.36E-08 21/126 R.TFDETVSTYVPLAQQVEDFHK[136.11]R[166.11].T sp|Q9ULW0|TPX2_HUMAN 1 2627.2987 2.44 90305 23472 4 2628.302562 657.8319 Targeting protein for Xklp2 OS=Homo sapiens OX=9606 GN=TPX2 PE=1 SV=2 4.75 3580.9 - 1.09E+06 - - - 382.1073 - 3.553 0.519 - 257.3 1 2 0 1.0039 22 0 0 0 2.43E+07 9.94E+06 - - - 3.8801 0.9999 221125_WJC_METTL3_EV_vs_WT_F06.23474.23474.4 0.00461 17/84 R.GPSWDPFRDWYPHSR.L "sp|P04792|HSPB1_HUMAN,tr|A0A6Q8PGY2|A0A6Q8PGY2_HUMAN,tr|A0A6Q8PHJ6|A0A6Q8PHJ6_HUMAN,tr|A0A6Q8PHA6|A0A6Q8PHA6_HUMAN,tr|A0A6Q8PF43|A0A6Q8PF43_HUMAN,tr|A0A6Q8PFK8|A0A6Q8PFK8_HUMAN,tr|A0A6Q8PGK1|A0A6Q8PGK1_HUMAN,tr|A0A6Q8PH65|A0A6Q8PH65_HUMAN,tr|A0A6Q8PFE7|A0A6Q8PFE7_HUMAN" 9 1901.8598 1.7 90307 23474 4 1901.861367 476.4722 Heat shock protein beta-1 OS=Homo sapiens OX=9606 GN=HSPB1 PE=1 SV=2 6.75 3581.2 - 665646 - - - 0.8418 - 2.935 0.499 - 247.8 1 2 1 0.0016 15 0 0 0 6.38E+07 3.76E+07 - - - 3.9541 0.9999 221125_WJC_METTL3_EV_vs_WT_F06.23475.23475.4 1.13E-07 16/84 R.GPSWDPFR[166.11]DWYPHSR[166.11].L "sp|P04792|HSPB1_HUMAN,tr|A0A6Q8PGY2|A0A6Q8PGY2_HUMAN,tr|A0A6Q8PHJ6|A0A6Q8PHJ6_HUMAN,tr|A0A6Q8PHA6|A0A6Q8PHA6_HUMAN,tr|A0A6Q8PF43|A0A6Q8PF43_HUMAN,tr|A0A6Q8PFK8|A0A6Q8PFK8_HUMAN,tr|A0A6Q8PGK1|A0A6Q8PGK1_HUMAN,tr|A0A6Q8PH65|A0A6Q8PH65_HUMAN,tr|A0A6Q8PFE7|A0A6Q8PFE7_HUMAN" 9 1921.8763 1.7 90308 23475 4 1921.877063 481.4764 Heat shock protein beta-1 OS=Homo sapiens OX=9606 GN=HSPB1 PE=1 SV=2 6.75 3581.3 - 435752 - - - 0.3939 - 2.642 0.539 - 204.8 1 2 1 0.0008 15 0 0 0 6.37E+07 3.76E+07 - - - 4.2649 1 221125_WJC_METTL3_EV_vs_WT_F06.23479.23479.3 1.03E-09 16/68 R.TSQNSELNNMQDLVEDYK.K sp|P35908|K22E_HUMAN 1 2126.9426 2377.02 90310 23479 3 2126.944294 709.9882 "Keratin, type II cytoskeletal 2 epidermal OS=Homo sapiens OX=9606 GN=KRT2 PE=1 SV=2" 3.92 3581.9 - 3.85E+06 - - - 0.7833 - 3.423 0.635 - 333.4 1 2 0 0.0017 18 0 0 0 1.75E+08 7.35E+04 - - - 8.6833 1 221125_WJC_METTL3_EV_vs_WT_F06.23480.23480.3 0.0105 21/56 K.HSGNITFDEIVNIAR.Q sp|P30050|RL12_HUMAN 1 1684.8533 1.44 90311 23480 3 1684.853265 562.625 60S ribosomal protein L12 OS=Homo sapiens OX=9606 GN=RPL12 PE=1 SV=1 5.32 3581.9 - 2.11E+06 - - - -0.0107 - 3.598 0.587 - 721.6 1 2 0 0 15 0 0 0 6.83E+07 4.75E+07 - - - 8.4254 1 221125_WJC_METTL3_EV_vs_WT_F06.23481.23481.2 7.39E-09 15/34 R.TSQNSELNNMQDLVEDYK.K sp|P35908|K22E_HUMAN 1 2126.9426 999 90312 23481 2 2126.944647 1064.4786 "Keratin, type II cytoskeletal 2 epidermal OS=Homo sapiens OX=9606 GN=KRT2 PE=1 SV=2" 3.92 3582 - 1.90E+06 - - - 0.9492 - 3.526 0.632 - 639.1 1 2 0 0.002 18 0 0 0 8.51E+07 0.00E+00 - - - 6.8065 1 221125_WJC_METTL3_EV_vs_WT_F06.23483.23483.3 1.09E-11 28/120 R.KYTLPPGVDPTQVSSSLSPEGTLTVEAPMPK.L "sp|P04792|HSPB1_HUMAN,tr|A0A6Q8PGK1|A0A6Q8PGK1_HUMAN" 2 3225.6479 2.77 90314 23483 3 3225.653944 1076.2232 Heat shock protein beta-1 OS=Homo sapiens OX=9606 GN=HSPB1 PE=1 SV=2 4.68 3582.2 - 1.40E+06 - - - 1.8747 - 5.197 0.649 - 536.9 1 2 0 0.006 31 0 0 0 1.11E+08 4.02E+07 - - - 9.5657 1 221125_WJC_METTL3_EV_vs_WT_F06.23484.23484.3 5.19E-12 25/116 R.EVTTGADSNGEMSPAELLHFQQQQALQVAR.Q "sp|Q8IVH2|FOXP4_HUMAN,tr|B7ZBM3|B7ZBM3_HUMAN" 2 3254.5626 8.97 90315 23484 3 3254.565258 1085.8615 Forkhead box protein P4 OS=Homo sapiens OX=9606 GN=FOXP4 PE=1 SV=1 4.4 3582.4 - 1.06E+06 - - - 0.8155 - 5.056 0.705 - 616.1 1 2 0 0.0027 30 0 0 0 1.69E+07 1.88E+06 - - - 10.1277 0.9997 221125_WJC_METTL3_EV_vs_WT_F06.23485.23485.3 0.000933 14/56 R.GPSWDPFRDWYPHSR.L "sp|P04792|HSPB1_HUMAN,tr|A0A6Q8PGY2|A0A6Q8PGY2_HUMAN,tr|A0A6Q8PHJ6|A0A6Q8PHJ6_HUMAN,tr|A0A6Q8PHA6|A0A6Q8PHA6_HUMAN,tr|A0A6Q8PF43|A0A6Q8PF43_HUMAN,tr|A0A6Q8PFK8|A0A6Q8PFK8_HUMAN,tr|A0A6Q8PGK1|A0A6Q8PGK1_HUMAN,tr|A0A6Q8PH65|A0A6Q8PH65_HUMAN,tr|A0A6Q8PFE7|A0A6Q8PFE7_HUMAN" 9 1901.8598 1.65 90316 23485 3 1901.860868 634.9605 Heat shock protein beta-1 OS=Homo sapiens OX=9606 GN=HSPB1 PE=1 SV=2 6.75 3582.5 - 589296 - - - 0.5794 - 2.174 0.454 - 173.4 1 2 1 0.0011 15 0 0 0 2.33E+07 1.41E+07 - - - 5.6277 0.9999 221125_WJC_METTL3_EV_vs_WT_F06.23488.23488.4 4.75E-10 18/108 R.GR[166.11]PDSLLAYLEQAGASPHR[166.11].V sp|Q9P253|VPS18_HUMAN 1 2057.0557 0.2 90319 23488 4 2057.061353 515.2712 Vacuolar protein sorting-associated protein 18 homolog OS=Homo sapiens OX=9606 GN=VPS18 PE=1 SV=2 6.75 3582.9 - 287405 - - - 2.735 - 3.431 0.497 - 305.1 1 2 0 0.0056 19 0 0 0 6.20E+05 3.09E+06 - - - 3.9674 1 221125_WJC_METTL3_EV_vs_WT_F06.23491.23491.3 4.74E-11 15/56 K.HSGNITFDEIVNIAR[166.11].Q sp|P30050|RL12_HUMAN 1 1694.8616 1.44 90320 23491 3 1694.86126 565.9611 60S ribosomal protein L12 OS=Homo sapiens OX=9606 GN=RPL12 PE=1 SV=1 5.32 3583.3 - 2.68E+06 - - - -0.1729 - 3.279 0.657 - 328 1 2 0 -0.0003 15 0 0 0 6.83E+07 4.75E+07 - - - 8.9635 1 221125_WJC_METTL3_EV_vs_WT_F06.23493.23493.3 3.36E-12 23/84 R.KDDASESTSLSALVTNSDLSLR.K sp|Q9NVK5|FGOP2_HUMAN 1 2308.1394 4.35 90322 23493 3 2308.145164 770.3871 FGFR1 oncogene partner 2 OS=Homo sapiens OX=9606 GN=FGFR1OP2 PE=1 SV=1 4.23 3583.5 - 1.43E+06 - - - 2.4912 - 3.957 0.646 - 546.7 1 2 0 0.0057 22 0 0 0 1.98E+07 4.54E+06 - - - 9.0017 1 221125_WJC_METTL3_EV_vs_WT_F06.23497.23497.3 1.43E-16 43/124 R.K[136.11]ELEQVC[160.03]NPIISGLYQGAGGPGPGGFGAQGPK[136.11].G "sp|P0DMV8|HS71A_HUMAN,sp|P0DMV9|HS71B_HUMAN,tr|V9GZ37|V9GZ37_HUMAN,tr|A0A0G2JIW1|A0A0G2JIW1_HUMAN" 4 3198.6103 0.13 90324 23497 3 3198.611084 1067.2107 Heat shock 70 kDa protein 1A OS=Homo sapiens OX=9606 GN=HSPA1A PE=1 SV=1 6.13 3584 - 2.38E+06 - - - 0.2504 - 6.787 0.728 - 2116 1 2 0 0.0008 32 0 0 0 1.60E+07 1.24E+08 - - - 11.062 0.9999 221125_WJC_METTL3_EV_vs_WT_F06.23498.23498.3 0.00537 16/96 K.QYNGVPLDGR[166.11]PMNIQLVTSQIDAQR[166.11].R "sp|Q86V81|THOC4_HUMAN,tr|E9PB61|E9PB61_HUMAN" 2 2832.4456 0.38 90325 23498 3 2832.451844 945.1558 THO complex subunit 4 OS=Homo sapiens OX=9606 GN=ALYREF PE=1 SV=3 5.96 3584.1 - 2.42E+06 - - - 2.2218 - 2.56 0.448 - 116 1 2 0 0.0063 25 0 0 0 1.55E+08 4.02E+08 - - - 5.6956 1 221125_WJC_METTL3_EV_vs_WT_F06.23499.23499.3 2.24E-06 20/96 K.QYNGVPLDGRPMNIQLVTSQIDAQR.R "sp|Q86V81|THOC4_HUMAN,tr|E9PB61|E9PB61_HUMAN" 2 2812.429 0.38 90326 23499 3 2812.43347 938.4836 THO complex subunit 4 OS=Homo sapiens OX=9606 GN=ALYREF PE=1 SV=3 5.96 3584.3 - 1.56E+06 - - - 1.5855 - 2.616 0.524 - 228.9 1 2 0 0.0045 25 0 0 0 1.55E+08 4.02E+08 - - - 6.5932 1 221125_WJC_METTL3_EV_vs_WT_F06.23500.23500.3 3.02E-11 22/132 R.GSSYLISAPEGGSVEC[160.03]VDQHSQGTGAYYMETYLK.K sp|Q9HCJ3|RAVR2_HUMAN 1 3683.6396 1.76 90327 23500 3 3683.644824 1228.8871 Ribonucleoprotein PTB-binding 2 OS=Homo sapiens OX=9606 GN=RAVER2 PE=1 SV=2 4.4 3584.4 - 1.02E+06 - - - 1.4198 - 4.145 0.711 - 217.8 1 2 0 0.0052 34 0 0 0 9.34E+06 5.32E+06 - - - 9.7368 1 221125_WJC_METTL3_EV_vs_WT_F06.23501.23501.3 8.45E-15 25/120 R.K[136.11]YTLPPGVDPTQVSSSLSPEGTLTVEAPMPK[136.11].L "sp|P04792|HSPB1_HUMAN,tr|A0A6Q8PGK1|A0A6Q8PGK1_HUMAN" 2 3241.6763 2.77 90328 23501 3 3241.681886 1081.566 Heat shock protein beta-1 OS=Homo sapiens OX=9606 GN=HSPB1 PE=1 SV=2 4.68 3584.5 - 861434 - - - 1.7241 - 5.004 0.694 - 523.9 1 2 0 0.0056 31 0 0 0 1.11E+08 4.02E+07 - - - 9.9804 1 221125_WJC_METTL3_EV_vs_WT_F06.23503.23503.3 2.26E-12 20/108 R.ASSDLSIASSEEDKLSQNAC[160.03]ILESVSEK.T sp|Q9H2G2|SLK_HUMAN 1 2996.4132 0.6 90330 23503 3 2996.421435 999.8117 STE20-like serine\threonine-protein kinase OS=Homo sapiens OX=9606 GN=SLK PE=1 SV=1 4.08 3584.8 - 507830 - - - 2.7463 - 4.154 0.687 - 560 1 2 1 0.0082 28 0 0 0 2.67E+06 4.46E+06 - - - 9.4734 1 221125_WJC_METTL3_EV_vs_WT_F06.23504.23504.3 1.46E-16 27/100 F.NHFSSLFDSSQVPANQGWGDGPLSSR.V "sp|Q8IWZ3|ANKH1_HUMAN,tr|A0A0A0MQZ8|A0A0A0MQZ8_HUMAN,tr|H0Y472|H0Y472_HUMAN,tr|H0Y7Y3|H0Y7Y3_HUMAN,tr|H0Y4P6|H0Y4P6_HUMAN,tr|H7C0V5|H7C0V5_HUMAN,tr|H0Y785|H0Y785_HUMAN" 7 2789.2794 1.31 90331 23504 3 2789.284808 930.7671 Ankyrin repeat and KH domain-containing protein 1 OS=Homo sapiens OX=9606 GN=ANKHD1 PE=1 SV=1 5.21 3584.9 - 428046 - - - 1.9496 - 4.274 0.722 - 662.4 1 1 0 0.0054 26 0 0 0 1.21E+07 9.22E+06 - - - 9.9299 0.9999 221125_WJC_METTL3_EV_vs_WT_F06.23511.23511.3 6.81E-08 18/56 R.GPSWDPFR[166.11]DWYPHSR[166.11].L "sp|P04792|HSPB1_HUMAN,tr|A0A6Q8PGY2|A0A6Q8PGY2_HUMAN,tr|A0A6Q8PHJ6|A0A6Q8PHJ6_HUMAN,tr|A0A6Q8PHA6|A0A6Q8PHA6_HUMAN,tr|A0A6Q8PF43|A0A6Q8PF43_HUMAN,tr|A0A6Q8PFK8|A0A6Q8PFK8_HUMAN,tr|A0A6Q8PGK1|A0A6Q8PGK1_HUMAN,tr|A0A6Q8PH65|A0A6Q8PH65_HUMAN,tr|A0A6Q8PFE7|A0A6Q8PFE7_HUMAN" 9 1921.8763 1.66 90336 23511 3 1921.877787 641.6327 Heat shock protein beta-1 OS=Homo sapiens OX=9606 GN=HSPB1 PE=1 SV=2 6.75 3585.9 - 1.28E+06 - - - 0.7706 - 3.122 0.59 - 352.8 1 2 1 0.0015 15 0 0 0 2.36E+07 1.42E+07 - - - 8.0882 1 221125_WJC_METTL3_EV_vs_WT_F06.23512.23512.4 6.26E-10 18/198 R.GSSYLISAPEGGSVEC[160.03]VDQHSQGTGAYYMETYLK.K sp|Q9HCJ3|RAVR2_HUMAN 1 3683.6396 2.67 90337 23512 4 3683.631998 921.9172 Ribonucleoprotein PTB-binding 2 OS=Homo sapiens OX=9606 GN=RAVER2 PE=1 SV=2 4.4 3586 - 794808 - - - -2.0621 - 3.825 0.612 - 148.3 1 2 0 -0.0076 34 0 0 0 6.84E+06 2.57E+06 - - - 4.9508 0.9997 221125_WJC_METTL3_EV_vs_WT_F06.23514.23514.4 8.18E-05 Nov-90 K.MQSINEDLK[136.11]DILHAAK[136.11].Q "sp|Q8N3C0|ASCC3_HUMAN,tr|E5RFZ0|E5RFZ0_HUMAN" 2 1840.9688 0.92 90339 23514 4 1840.96858 461.2495 Activating signal cointegrator 1 complex subunit 3 OS=Homo sapiens OX=9606 GN=ASCC3 PE=1 SV=3 5.36 3586.3 - 469706 - - - -0.1108 - 1.632 0.465 - 73.1 1 2 1 -0.0002 16 0 0 0 2.32E+06 2.53E+06 - - - 3.4458 1 221125_WJC_METTL3_EV_vs_WT_F06.23519.23519.4 0.000491 20/108 R.FAHIDGDHLTLLNVYHAFK[136.11].Q sp|O43143|DHX15_HUMAN 1 2218.1415 0.82 90343 23519 4 2218.141247 555.5426 Pre-mRNA-splicing factor ATP-dependent RNA helicase DHX15 OS=Homo sapiens OX=9606 GN=DHX15 PE=1 SV=2 6.26 3586.8 - 1.10E+06 - - - -0.1019 - 3.92 0.513 - 433 1 2 0 -0.0002 19 0 0 0 2.06E+07 2.52E+07 - - - 4.1532 1 221125_WJC_METTL3_EV_vs_WT_F06.23524.23524.4 1.55E-13 35/186 R.K[136.11]ELEQVC[160.03]NPIISGLYQGAGGPGPGGFGAQGPK[136.11].G "sp|P0DMV8|HS71A_HUMAN,sp|P0DMV9|HS71B_HUMAN,tr|V9GZ37|V9GZ37_HUMAN,tr|A0A0G2JIW1|A0A0G2JIW1_HUMAN" 4 3198.6103 0.37 90346 23524 4 3198.610859 800.6598 Heat shock 70 kDa protein 1A OS=Homo sapiens OX=9606 GN=HSPA1A PE=1 SV=1 6.13 3587.4 - 3.11E+06 - - - 0.1801 - 5.699 0.676 - 1011.9 1 2 0 0.0006 32 0 0 0 2.68E+07 7.26E+07 - - - 5.6352 1 221125_WJC_METTL3_EV_vs_WT_F06.23528.23528.4 6.45E-13 23/126 K.C[160.03]QEVISWLDANTLAEK[136.11]DEFEHK[136.11].R "sp|P0DMV8|HS71A_HUMAN,sp|P0DMV9|HS71B_HUMAN,tr|V9GZ37|V9GZ37_HUMAN,tr|A0A0G2JIW1|A0A0G2JIW1_HUMAN" 4 2677.2665 0.11 90350 23528 4 2677.267143 670.3239 Heat shock 70 kDa protein 1A OS=Homo sapiens OX=9606 GN=HSPA1A PE=1 SV=1 4.35 3587.7 - 1.88E+06 - - - 0.2469 - 4.057 0.649 - 461.4 1 2 1 0.0007 22 0 0 0 1.44E+07 1.35E+08 - - - 5.3329 1 221125_WJC_METTL3_EV_vs_WT_F06.23529.23529.3 7.42E-08 32/100 K.AK[136.11]C[160.03]ELSSSVQTDINLPYLTMDSSGPK[136.11].H "sp|P38646|GRP75_HUMAN,tr|H0Y8K0|H0Y8K0_HUMAN,tr|A0A7I2V2G2|A0A7I2V2G2_HUMAN,tr|A0A7I2V3F7|A0A7I2V3F7_HUMAN,tr|A0A7I2YQB2|A0A7I2YQB2_HUMAN,tr|D6RCD7|D6RCD7_HUMAN" 6 2856.3856 0.23 90351 23529 3 2856.38621 953.1358 "Stress-70 protein, mitochondrial OS=Homo sapiens OX=9606 GN=HSPA9 PE=1 SV=2" 4.56 3587.9 - 1.57E+06 - - - 0.2097 - 4.886 0.637 - 711.3 1 2 1 0.0006 26 0 0 0 3.46E+07 1.49E+08 - - - 9.2914 0.9897 221125_WJC_METTL3_EV_vs_WT_F06.23530.23530.4 0.00418 17/144 K.QYNGVPLDGRPMNIQLVTSQIDAQR.R "sp|Q86V81|THOC4_HUMAN,tr|E9PB61|E9PB61_HUMAN" 2 2812.429 0.38 90352 23530 4 2812.447381 704.1145 THO complex subunit 4 OS=Homo sapiens OX=9606 GN=ALYREF PE=1 SV=3 5.96 3588 - 1.37E+06 - - - 6.5317 - 2.716 0.355 - 195.2 1 2 0 0.0184 25 0 0 0 1.83E+07 4.83E+07 - - - 2.6287 1 221125_WJC_METTL3_EV_vs_WT_F06.23533.23533.3 3.50E-12 22/100 F.NHFSSLFDSSQVPANQGWGDGPLSSR[166.11].V "sp|Q8IWZ3|ANKH1_HUMAN,tr|A0A0A0MQZ8|A0A0A0MQZ8_HUMAN,tr|H0Y472|H0Y472_HUMAN,tr|H0Y7Y3|H0Y7Y3_HUMAN,tr|H0Y4P6|H0Y4P6_HUMAN,tr|H7C0V5|H7C0V5_HUMAN,tr|H0Y785|H0Y785_HUMAN" 7 2799.2876 1.44 90355 23533 3 2799.303419 934.1032 Ankyrin repeat and KH domain-containing protein 1 OS=Homo sapiens OX=9606 GN=ANKHD1 PE=1 SV=1 5.21 3588.3 - 474701 - - - 5.6368 - 4.589 0.661 - 466.7 1 1 0 0.0158 26 0 0 0 1.35E+07 9.38E+06 - - - 9.4105 0.9999 221125_WJC_METTL3_EV_vs_WT_F06.23539.23539.4 2.55E-09 21/192 R.INSFEEHVASTSAALPSC[160.03]LPPEVPTQLPGQNMK.G sp|Q16875|F263_HUMAN 1 3548.728 4.41 90358 23539 4 3548.744228 888.1893 "6-phosphofructo-2-kinase\fructose-2,6-bisphosphatase 3 OS=Homo sapiens OX=9606 GN=PFKFB3 PE=1 SV=1" 4.75 3589.1 - 640127 - - - 4.5856 - 3.259 0.617 - 157.9 1 2 0 0.0163 33 0 0 0 1.10E+07 2.48E+06 - - - 4.9463 1 221125_WJC_METTL3_EV_vs_WT_F06.23545.23545.3 1.01E-13 24/72 C.HIFASFNDTFVHVTDLSGK.E "sp|P62263|RS14_HUMAN,tr|A0A2R8Y811|A0A2R8Y811_HUMAN,tr|E5RH77|E5RH77_HUMAN" 3 2134.0484 1.5 90362 23545 3 2134.04867 712.3567 40S ribosomal protein S14 OS=Homo sapiens OX=9606 GN=RPS14 PE=1 SV=3 5.98 3589.8 - 793069 - - - 0.1481 - 4.728 0.691 - 553.3 1 1 0 0.0003 19 0 0 0 1.87E+07 1.24E+07 - - - 10.0605 0.9995 221125_WJC_METTL3_EV_vs_WT_F06.23553.23553.4 0.00476 19/144 K.QYNGVPLDGR[166.11]PMNIQLVTSQIDAQR[166.11].R "sp|Q86V81|THOC4_HUMAN,tr|E9PB61|E9PB61_HUMAN" 2 2832.4456 0.38 90368 23553 4 2832.452764 709.1187 THO complex subunit 4 OS=Homo sapiens OX=9606 GN=ALYREF PE=1 SV=3 5.96 3590.9 - 2.24E+06 - - - 2.5466 - 3.143 0.37 - 216 1 2 0 0.0072 25 0 0 0 1.85E+07 4.83E+07 - - - 2.8088 1 221125_WJC_METTL3_EV_vs_WT_F06.23554.23554.3 1.12E-09 27/100 K.AKC[160.03]ELSSSVQTDINLPYLTMDSSGPK.H "sp|P38646|GRP75_HUMAN,tr|H0Y8K0|H0Y8K0_HUMAN,tr|A0A7I2V2G2|A0A7I2V2G2_HUMAN,tr|A0A7I2V3F7|A0A7I2V3F7_HUMAN,tr|A0A7I2YQB2|A0A7I2YQB2_HUMAN,tr|D6RCD7|D6RCD7_HUMAN" 6 2840.3572 0.23 90369 23554 3 2840.351571 947.793 "Stress-70 protein, mitochondrial OS=Homo sapiens OX=9606 GN=HSPA9 PE=1 SV=2" 4.56 3591 - 1.24E+06 - - - -1.9857 - 4.65 0.644 - 516.2 1 2 1 -0.0056 26 0 0 0 3.46E+07 1.49E+08 - - - 9.2542 1 221125_WJC_METTL3_EV_vs_WT_F06.23555.23555.3 2.36E-10 17/84 K.C[160.03]QEVISWLDANTLAEK[136.11]DEFEHK[136.11].R "sp|P0DMV8|HS71A_HUMAN,sp|P0DMV9|HS71B_HUMAN,tr|V9GZ37|V9GZ37_HUMAN,tr|A0A0G2JIW1|A0A0G2JIW1_HUMAN" 4 2677.2665 0.06 90370 23555 3 2677.266831 893.4294 Heat shock 70 kDa protein 1A OS=Homo sapiens OX=9606 GN=HSPA1A PE=1 SV=1 4.35 3591.1 - 456809 - - - 0.1304 - 4.088 0.648 - 284.5 1 2 1 0.0003 22 0 0 0 7.36E+05 1.24E+07 - - - 9.1027 0.9999 221125_WJC_METTL3_EV_vs_WT_F06.23559.23559.3 2.93E-12 17/100 R.GNQLVDLAPLGYNYTVNYTTHTQTNK.T "sp|Q86UW9|DTX2_HUMAN,tr|E7ET89|E7ET89_HUMAN" 2 2924.4305 4.13 90372 23559 3 2924.442887 975.8174 Probable E3 ubiquitin-protein ligase DTX2 OS=Homo sapiens OX=9606 GN=DTX2 PE=1 SV=3 6.74 3591.6 - 611800 - - - 4.2525 - 3.458 0.621 - 268.2 1 2 0 0.0124 26 0 0 0 7.98E+06 1.93E+06 - - - 8.3145 1 221125_WJC_METTL3_EV_vs_WT_F06.23560.23560.3 8.01E-14 23/124 R.GGGGSFGYSYGGGSGGGFSASSLGGGFGGGSR.G sp|P35527|K1C9_HUMAN 1 2704.1538 10.57 90373 23560 3 2704.157385 902.3919 "Keratin, type I cytoskeletal 9 OS=Homo sapiens OX=9606 GN=KRT9 PE=1 SV=3" 8.59 3591.8 - 777342 - - - 1.3128 - 4.036 0.756 - 273.5 1 2 0 0.0035 32 0 0 0 2.69E+07 2.54E+06 - - - 10.1776 1 221125_WJC_METTL3_EV_vs_WT_F06.23566.23566.4 2.78E-08 17/168 K.YGKDATNVGDEGGFAPNILENKEGLELLK.T "sp|P06733|ENOA_HUMAN,tr|A0A2R8Y6G6|A0A2R8Y6G6_HUMAN" 2 3090.551 4.35 90377 23566 4 3090.555995 773.645 Alpha-enolase OS=Homo sapiens OX=9606 GN=ENO1 PE=1 SV=2 4.36 3592.6 - 580196 - - - 1.6292 - 3.621 0.655 - 102.8 1 2 2 0.005 29 0 0 0 1.15E+07 2.64E+06 - - - 5.3223 1 221125_WJC_METTL3_EV_vs_WT_F06.23572.23572.4 2.67E-07 15/132 R.K[136.11]NNFSDTGNFGFGIQEHIDLGIK[136.11].Y "sp|P62913|RL11_HUMAN,tr|Q5VVC8|Q5VVC8_HUMAN" 2 2566.2787 0.35 90380 23572 4 2566.277404 642.577 60S ribosomal protein L11 OS=Homo sapiens OX=9606 GN=RPL11 PE=1 SV=2 5.38 3593.4 - 449235 - - - -0.5058 - 3.167 0.511 - 159.7 1 2 0 -0.0013 23 0 0 0 3.50E+06 9.98E+06 - - - 4.0469 1 221125_WJC_METTL3_EV_vs_WT_F06.23573.23573.3 2.78E-06 16/132 K.QIPFPSGTPLHANSMVSENVIQSTAVTTVSSGTK.E "sp|Q12904|AIMP1_HUMAN,tr|A0A804HJ47|A0A804HJ47_HUMAN,tr|D6R937|D6R937_HUMAN,tr|A0A5F9ZHC5|A0A5F9ZHC5_HUMAN" 4 3484.7508 1.44 90381 23573 3 3484.752763 1162.5909 Aminoacyl tRNA synthase complex-interacting multifunctional protein 1 OS=Homo sapiens OX=9606 GN=AIMP1 PE=1 SV=2 6.75 3593.5 - 546380 - - - 0.5636 - 3.358 0.619 - 233.7 1 2 0 0.002 34 0 0 0 2.86E+07 1.99E+07 - - - 8.2276 0.9429 221125_WJC_METTL3_EV_vs_WT_F06.23574.23574.3 2.15E-05 13/116 K.TPSTMENDSSNLDPSQAPSLAQPLVFSNSK.Q "sp|Q14157|UBP2L_HUMAN,tr|F8W726|F8W726_HUMAN,tr|Q5VU77|Q5VU77_HUMAN" 3 3161.4823 0.88 90382 23574 3 3162.467758 1054.8347 Ubiquitin-associated protein 2-like OS=Homo sapiens OX=9606 GN=UBAP2L PE=1 SV=2 4.03 3593.6 - 447721 - - - 311.7114 - 1.728 0.526 - 66.8 1 2 0 0.9855 30 0 0 0 1.97E+06 2.23E+06 - - - 5.3898 0.9999 221125_WJC_METTL3_EV_vs_WT_F06.23577.23577.4 1.10E-06 21/126 K.C[160.03]QEVISWLDANTLAEKDEFEHK.R "sp|P0DMV8|HS71A_HUMAN,sp|P0DMV9|HS71B_HUMAN,tr|V9GZ37|V9GZ37_HUMAN,tr|A0A0G2JIW1|A0A0G2JIW1_HUMAN" 4 2661.2381 0.11 90383 23577 4 2661.240099 666.3168 Heat shock 70 kDa protein 1A OS=Homo sapiens OX=9606 GN=HSPA1A PE=1 SV=1 4.35 3594 - 1.21E+06 - - - 0.7579 - 4.213 0.566 - 432.5 1 2 1 0.002 22 0 0 0 1.44E+07 1.35E+08 - - - 4.6225 1 221125_WJC_METTL3_EV_vs_WT_F06.23580.23580.3 3.88E-11 20/132 K.QIPFPSGTPLHANSMVSENVIQSTAVTTVSSGTK[136.11].E "sp|Q12904|AIMP1_HUMAN,tr|A0A804HJ47|A0A804HJ47_HUMAN,tr|D6R937|D6R937_HUMAN,tr|A0A5F9ZHC5|A0A5F9ZHC5_HUMAN" 4 3492.765 1.44 90386 23580 3 3492.767533 1165.2623 Aminoacyl tRNA synthase complex-interacting multifunctional protein 1 OS=Homo sapiens OX=9606 GN=AIMP1 PE=1 SV=2 6.75 3594.4 - 794838 - - - 0.7255 - 3.637 0.643 - 309 1 2 0 0.0025 34 0 0 0 2.86E+07 1.99E+07 - - - 8.6786 1 221125_WJC_METTL3_EV_vs_WT_F06.23582.23582.3 1.24E-08 17/72 K.DTSEDIEELVEPVAAHGPK.L "sp|Q99460|PSMD1_HUMAN,tr|A0A7I2V523|A0A7I2V523_HUMAN,tr|A0A7I2V641|A0A7I2V641_HUMAN,tr|A0A087WW66|A0A087WW66_HUMAN,tr|A0A7P0MW50|A0A7P0MW50_HUMAN,tr|A0A7I2V479|A0A7I2V479_HUMAN" 6 2034.9746 0.67 90388 23582 3 2034.977096 679.3321 26S proteasome non-ATPase regulatory subunit 1 OS=Homo sapiens OX=9606 GN=PSMD1 PE=1 SV=2 4.08 3594.7 - 397787 - - - 1.2364 - 3.056 0.641 - 284.3 1 2 0 0.0025 19 0 0 0 1.21E+07 1.81E+07 - - - 8.4303 0.9999 221125_WJC_METTL3_EV_vs_WT_F06.23587.23587.4 5.17E-08 21/198 K.QIPFPSGTPLHANSMVSENVIQSTAVTTVSSGTK.E "sp|Q12904|AIMP1_HUMAN,tr|A0A804HJ47|A0A804HJ47_HUMAN,tr|D6R937|D6R937_HUMAN,tr|A0A5F9ZHC5|A0A5F9ZHC5_HUMAN" 4 3484.7508 1.1 90391 23587 4 3484.759817 872.195 Aminoacyl tRNA synthase complex-interacting multifunctional protein 1 OS=Homo sapiens OX=9606 GN=AIMP1 PE=1 SV=2 6.75 3595.3 - 1.67E+06 - - - 2.5878 - 3.613 0.53 - 233.3 1 2 0 0.009 34 0 0 0 2.02E+07 1.84E+07 - - - 4.2197 0.9997 221125_WJC_METTL3_EV_vs_WT_F06.23588.23588.3 1.44E-09 19/68 K.YVHYEIDAC[160.03]MDSEAPGSK[136.11].D "sp|Q86U44|MTA70_HUMAN,tr|H0YFV6|H0YFV6_HUMAN" 2 2078.8805 0.001 90392 23588 3 2079.881101 693.9674 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 4.31 3595.4 - 900972 - - - 481.3211 - 3.172 0.65 - 385.5 1 2 0 1.0006 18 0 0 0 0.00E+00 3.99E+07 - - - 8.3842 1 221125_WJC_METTL3_EV_vs_WT_F06.23597.23597.4 1.19E-12 26/156 Q.KEEYQGVIAWQGDYGEFVIKDPDEVAR.L "sp|A0A1W2PQ73|ERFL_HUMAN,sp|P50548|ERF_HUMAN" 2 3140.5091 1.41 90398 23597 4 3140.512652 786.1346 ETS domain-containing transcription factor ERF-like OS=Homo sapiens OX=9606 GN=ERFL PE=3 SV=1 4.2 3596.6 - 1.23E+06 - - - 1.1326 - 4.578 0.646 - 369 1 1 1 0.0036 27 0 0 0 1.06E+07 7.55E+06 - - - 5.3238 1 221125_WJC_METTL3_EV_vs_WT_F06.23598.23598.3 1.39E-08 17/72 K.DTSEDIEELVEPVAAHGPK[136.11].L "sp|Q99460|PSMD1_HUMAN,tr|A0A7I2V523|A0A7I2V523_HUMAN,tr|A0A7I2V641|A0A7I2V641_HUMAN,tr|A0A087WW66|A0A087WW66_HUMAN,tr|A0A7P0MW50|A0A7P0MW50_HUMAN,tr|A0A7I2V479|A0A7I2V479_HUMAN" 6 2042.9888 0.66 90399 23598 3 2042.987309 682.0035 26S proteasome non-ATPase regulatory subunit 1 OS=Homo sapiens OX=9606 GN=PSMD1 PE=1 SV=2 4.08 3596.7 - 737975 - - - -0.72 - 3.233 0.557 - 298.5 1 2 0 -0.0015 19 0 0 0 1.20E+07 1.81E+07 - - - 7.6324 1 221125_WJC_METTL3_EV_vs_WT_F06.23604.23604.4 4.35E-10 19/198 K.QIPFPSGTPLHANSMVSENVIQSTAVTTVSSGTK[136.11].E "sp|Q12904|AIMP1_HUMAN,tr|A0A804HJ47|A0A804HJ47_HUMAN,tr|D6R937|D6R937_HUMAN,tr|A0A5F9ZHC5|A0A5F9ZHC5_HUMAN" 4 3492.765 1.1 90403 23604 4 3492.77136 874.1985 Aminoacyl tRNA synthase complex-interacting multifunctional protein 1 OS=Homo sapiens OX=9606 GN=AIMP1 PE=1 SV=2 6.75 3597.4 - 1.14E+06 - - - 1.8212 - 3.64 0.551 - 187 1 2 0 0.0064 34 0 0 0 2.03E+07 1.84E+07 - - - 4.4054 1 221125_WJC_METTL3_EV_vs_WT_F06.23605.23605.4 4.80E-05 19/162 R.QVASHVGLHSASIPGILALDLC[160.03]PSDTNK[136.11].L "sp|Q9UMS4|PRP19_HUMAN,tr|F5GY56|F5GY56_HUMAN" 2 2907.5004 1.14 90404 23605 4 2907.497684 727.8824 Pre-mRNA-processing factor 19 OS=Homo sapiens OX=9606 GN=PRPF19 PE=1 SV=1 5.98 3597.5 - 839426 - - - -0.9314 - 3.31 0.479 - 182.8 1 2 0 -0.0027 28 0 0 0 1.85E+08 1.62E+08 - - - 3.7661 0.9984 221125_WJC_METTL3_EV_vs_WT_F06.23607.23607.4 1.02E-10 25/222 F.GAVGVAGSSLTSFGTETSNSGTLPQSSAVGSAFTQDTR[166.11].S "sp|Q8ND56|LS14A_HUMAN,tr|A0A140TA76|A0A140TA76_HUMAN,tr|K7EMZ9|K7EMZ9_HUMAN" 3 3641.7321 0.72 90406 23607 4 3641.734655 911.4403 Protein LSM14 homolog A OS=Homo sapiens OX=9606 GN=LSM14A PE=1 SV=3 4.37 3597.7 - 1.38E+06 - - - 0.712 - 4.497 0.609 - 218.5 1 1 0 0.0026 38 0 0 0 1.41E+07 1.96E+07 - - - 4.9644 1 221125_WJC_METTL3_EV_vs_WT_F06.23608.23608.3 1.30E-11 23/148 F.GAVGVAGSSLTSFGTETSNSGTLPQSSAVGSAFTQDTR.S "sp|Q8ND56|LS14A_HUMAN,tr|A0A140TA76|A0A140TA76_HUMAN,tr|K7EMZ9|K7EMZ9_HUMAN" 3 3631.7238 1.21 90407 23608 3 3631.734583 1211.5819 Protein LSM14 homolog A OS=Homo sapiens OX=9606 GN=LSM14A PE=1 SV=3 4.37 3597.8 - 954303 - - - 2.9713 - 4.211 0.625 - 339.5 1 1 0 0.0108 38 0 0 0 1.40E+07 1.16E+07 - - - 8.8128 1 221125_WJC_METTL3_EV_vs_WT_F06.23609.23609.3 5.29E-11 23/148 F.GAVGVAGSSLTSFGTETSNSGTLPQSSAVGSAFTQDTR[166.11].S "sp|Q8ND56|LS14A_HUMAN,tr|A0A140TA76|A0A140TA76_HUMAN,tr|K7EMZ9|K7EMZ9_HUMAN" 3 3641.7321 1.21 90408 23609 3 3641.737546 1214.918 Protein LSM14 homolog A OS=Homo sapiens OX=9606 GN=LSM14A PE=1 SV=3 4.37 3597.9 - 807874 - - - 1.5059 - 3.974 0.686 - 337.7 1 1 0 0.0055 38 0 0 0 1.40E+07 1.16E+07 - - - 9.3611 1 221125_WJC_METTL3_EV_vs_WT_F06.23611.23611.3 4.94E-09 15/60 R.HATALEELSEQLEQAK.R sp|P35580|MYH10_HUMAN 1 1795.8952 0.73 90410 23611 3 1795.899157 599.639 Myosin-10 OS=Homo sapiens OX=9606 GN=MYH10 PE=1 SV=3 4.48 3598.2 - 371927 - - - 2.1989 - 3.029 0.582 - 428.4 1 2 0 0.0039 16 0 0 0 3.86E+06 5.26E+06 - - - 7.8712 1 221125_WJC_METTL3_EV_vs_WT_F06.23614.23614.4 9.46E-14 22/222 F.GAVGVAGSSLTSFGTETSNSGTLPQSSAVGSAFTQDTR.S "sp|Q8ND56|LS14A_HUMAN,tr|A0A140TA76|A0A140TA76_HUMAN,tr|K7EMZ9|K7EMZ9_HUMAN" 3 3631.7238 0.72 90411 23614 4 3631.728238 908.9382 Protein LSM14 homolog A OS=Homo sapiens OX=9606 GN=LSM14A PE=1 SV=3 4.37 3598.6 - 1.50E+06 - - - 1.2242 - 4.228 0.649 - 190.5 1 1 0 0.0044 38 0 0 0 1.41E+07 1.94E+07 - - - 5.2941 0.9999 221125_WJC_METTL3_EV_vs_WT_F06.23616.23616.3 1.40E-08 18/76 R.SDPNR[166.11]ETDDTLVLSFVGQTR[166.11].V "sp|Q16531|DDB1_HUMAN,tr|A0A7P0TAK7|A0A7P0TAK7_HUMAN,tr|A0A7P0T870|A0A7P0T870_HUMAN,tr|A0A7P0TB30|A0A7P0TB30_HUMAN,tr|A0A7P0Z3Z5|A0A7P0Z3Z5_HUMAN,tr|F5GY55|F5GY55_HUMAN,tr|A0A7P0Z4B9|A0A7P0Z4B9_HUMAN,tr|A0A7P0T965|A0A7P0T965_HUMAN" 8 2269.1089 0.76 90413 23616 3 2269.111198 757.3769 DNA damage-binding protein 1 OS=Homo sapiens OX=9606 GN=DDB1 PE=1 SV=1 4.23 3598.9 - 726469 - - - 0.9933 - 3.324 0.507 - 368.7 1 2 1 0.0023 20 0 0 0 5.39E+07 7.06E+07 - - - 7.106 1 221125_WJC_METTL3_EV_vs_WT_F06.23621.23621.4 6.25E-14 30/162 R.QVASHVGLHSASIPGILALDLC[160.03]PSDTNK.L "sp|Q9UMS4|PRP19_HUMAN,tr|F5GY56|F5GY56_HUMAN" 2 2899.4862 1.14 90416 23621 4 2899.48955 725.8788 Pre-mRNA-processing factor 19 OS=Homo sapiens OX=9606 GN=PRPF19 PE=1 SV=1 5.98 3599.5 - 1.08E+06 - - - 1.1581 - 4.825 0.645 - 495.8 1 2 0 0.0034 28 0 0 0 1.84E+08 1.61E+08 - - - 5.3278 1 221125_WJC_METTL3_EV_vs_WT_F06.23622.23622.3 6.12E-06 21/144 R.GAGFNQNNGAGSENFGLGVVPVSASPSSVEVHPVLEK[136.11].L "sp|Q7Z739|YTHD3_HUMAN,tr|A0A087X0Q1|A0A087X0Q1_HUMAN,tr|A0A024R7W5|A0A024R7W5_HUMAN,tr|A0A087WY31|A0A087WY31_HUMAN" 4 3658.8107 4.87 90417 23622 3 3659.798876 1220.6108 YTH domain-containing family protein 3 OS=Homo sapiens OX=9606 GN=YTHDF3 PE=1 SV=1 4.75 3599.6 - 1.21E+06 - - - 270.0801 - 3.928 0.639 - 241 1 2 0 0.9882 37 0 0 0 6.45E+06 1.32E+06 - - - 8.5381 0.9997 221125_WJC_METTL3_EV_vs_WT_F06.23634.23634.4 2.74E-06 18/96 K.DITELFSQLHVSSKPEK.L "sp|Q9NRY5|F1142_HUMAN,tr|E7ESJ7|E7ESJ7_HUMAN" 2 1957.0157 1.24 90427 23634 4 1957.019683 490.2612 Protein FAM114A2 OS=Homo sapiens OX=9606 GN=FAM114A2 PE=1 SV=4 5.45 3601.2 - 536535 - - - 2.0572 - 2.817 0.376 - 164.7 1 2 0 0.004 17 0 0 0 1.00E+08 8.09E+07 - - - 2.8572 1 221125_WJC_METTL3_EV_vs_WT_F06.23635.23635.4 3.55E-08 19/96 K.DITELFSQLHVSSK[136.11]PEK[136.11].L "sp|Q9NRY5|F1142_HUMAN,tr|E7ESJ7|E7ESJ7_HUMAN" 2 1973.0441 1.24 90428 23635 4 1973.04764 494.2683 Protein FAM114A2 OS=Homo sapiens OX=9606 GN=FAM114A2 PE=1 SV=4 5.45 3601.4 - 501768 - - - 1.816 - 3.223 0.541 - 176.6 1 2 0 0.0036 17 0 0 0 1.00E+08 8.09E+07 - - - 4.3402 1 221125_WJC_METTL3_EV_vs_WT_F06.23636.23636.3 5.89E-09 18/64 K.DITELFSQLHVSSKPEK.L "sp|Q9NRY5|F1142_HUMAN,tr|E7ESJ7|E7ESJ7_HUMAN" 2 1957.0157 1.18 90429 23636 3 1957.019976 653.3458 Protein FAM114A2 OS=Homo sapiens OX=9606 GN=FAM114A2 PE=1 SV=4 5.45 3601.5 - 303225 - - - 2.2069 - 3.403 0.572 - 275.5 1 2 0 0.0043 17 0 0 0 6.23E+07 5.27E+07 - - - 8.0099 0.9999 221125_WJC_METTL3_EV_vs_WT_F06.23639.23639.4 2.66E-08 25/114 K.KQELEVLTANIQDLKEEYSR.K "sp|Q9HBM1|SPC25_HUMAN,tr|C9JW94|C9JW94_HUMAN" 2 2405.2438 1.42 90430 23639 4 2405.249744 602.3182 Kinetochore protein Spc25 OS=Homo sapiens OX=9606 GN=SPC25 PE=1 SV=1 4.59 3601.9 - 1.14E+06 - - - 2.4634 - 4.713 0.573 - 676.7 1 2 1 0.0059 20 0 0 0 4.76E+07 3.36E+07 - - - 4.7301 1 221125_WJC_METTL3_EV_vs_WT_F06.23640.23640.3 1.07E-11 26/76 K.KQELEVLTANIQDLKEEYSR.K "sp|Q9HBM1|SPC25_HUMAN,tr|C9JW94|C9JW94_HUMAN" 2 2405.2438 3.04 90431 23640 3 2405.246417 802.7552 Kinetochore protein Spc25 OS=Homo sapiens OX=9606 GN=SPC25 PE=1 SV=1 4.59 3602 - 575472 - - - 1.0801 - 4.607 0.648 - 1078.1 1 2 1 0.0026 20 0 0 0 3.09E+07 1.02E+07 - - - 9.4698 1 221125_WJC_METTL3_EV_vs_WT_F06.23641.23641.3 1.16E-08 16/92 R.NGPGFHNDIDSNSTIQEILIPASK.V sp|Q96I24|FUBP3_HUMAN 1 2566.2663 2.53 90432 23641 3 2567.25731 856.4294 Far upstream element-binding protein 3 OS=Homo sapiens OX=9606 GN=FUBP3 PE=1 SV=2 4.54 3602.1 - 1.14E+06 - - - 386.1501 - 3.065 0.683 - 142.1 1 2 0 0.991 24 0 0 0 6.08E+06 2.41E+06 - - - 8.4817 1 221125_WJC_METTL3_EV_vs_WT_F06.23643.23643.3 6.20E-12 19/144 R.GAGFNQNNGAGSENFGLGVVPVSASPSSVEVHPVLEK.L "sp|Q7Z739|YTHD3_HUMAN,tr|A0A087X0Q1|A0A087X0Q1_HUMAN,tr|A0A024R7W5|A0A024R7W5_HUMAN,tr|A0A087WY31|A0A087WY31_HUMAN" 4 3650.7965 3.74 90434 23643 3 3651.789421 1217.9394 YTH domain-containing family protein 3 OS=Homo sapiens OX=9606 GN=YTHDF3 PE=1 SV=1 4.75 3602.4 - 949670 - - - 271.9727 - 3.497 0.666 - 173.9 1 2 0 0.9929 37 0 0 0 6.78E+06 1.81E+06 - - - 8.5704 0.9999 221125_WJC_METTL3_EV_vs_WT_F06.23644.23644.3 6.49E-07 20/64 K.DITELFSQLHVSSK[136.11]PEK[136.11].L "sp|Q9NRY5|F1142_HUMAN,tr|E7ESJ7|E7ESJ7_HUMAN" 2 1973.0441 1.18 90435 23644 3 1973.05129 658.6886 Protein FAM114A2 OS=Homo sapiens OX=9606 GN=FAM114A2 PE=1 SV=4 5.45 3602.5 - 553131 - - - 3.6659 - 3.7 0.568 - 351.8 1 2 0 0.0072 17 0 0 0 6.23E+07 5.27E+07 - - - 8.1759 0.9998 221125_WJC_METTL3_EV_vs_WT_F06.23645.23645.3 3.62E-07 18/52 K.SLNNQFASFIDKVR.F sp|P04264|K2C1_HUMAN 1 1637.8526 283.36 90436 23645 3 1637.856537 546.9581 "Keratin, type II cytoskeletal 1 OS=Homo sapiens OX=9606 GN=KRT1 PE=1 SV=6" 8.46 3602.7 - 457787 - - - 2.4312 - 2.928 0.545 - 355.2 1 2 1 0.004 14 0 0 0 1.91E+07 6.73E+04 - - - 7.4701 0.9998 221125_WJC_METTL3_EV_vs_WT_F06.23646.23646.4 1.25E-07 18/180 R.KYTLPPGVDPTQVSSSLSPEGTLTVEAPMPK.L "sp|P04792|HSPB1_HUMAN,tr|A0A6Q8PGK1|A0A6Q8PGK1_HUMAN" 2 3225.6479 0.96 90437 23646 4 3225.663823 807.4193 Heat shock protein beta-1 OS=Homo sapiens OX=9606 GN=HSPB1 PE=1 SV=2 4.68 3602.8 - 377663 - - - 4.9373 - 3.228 0.562 - 153.1 1 2 0 0.0159 31 0 0 0 1.04E+07 1.09E+07 - - - 4.4694 1 221125_WJC_METTL3_EV_vs_WT_F06.23650.23650.3 3.94E-11 19/76 R.SDPNRETDDTLVLSFVGQTR.V "sp|Q16531|DDB1_HUMAN,tr|A0A7P0TAK7|A0A7P0TAK7_HUMAN,tr|A0A7P0T870|A0A7P0T870_HUMAN,tr|A0A7P0TB30|A0A7P0TB30_HUMAN,tr|A0A7P0Z3Z5|A0A7P0Z3Z5_HUMAN,tr|F5GY55|F5GY55_HUMAN,tr|A0A7P0Z4B9|A0A7P0Z4B9_HUMAN,tr|A0A7P0T965|A0A7P0T965_HUMAN" 8 2249.0924 0.76 90439 23650 3 2249.097103 750.7047 DNA damage-binding protein 1 OS=Homo sapiens OX=9606 GN=DDB1 PE=1 SV=1 4.23 3603.3 - 2.47E+06 - - - 2.0893 - 3.548 0.627 - 443 1 2 1 0.0047 20 0 0 0 5.39E+07 7.06E+07 - - - 8.6014 1 221125_WJC_METTL3_EV_vs_WT_F06.23652.23652.4 1.21E-12 34/174 R.LNSVQSSER[166.11]PLFLVHPIEGSTTVFHSLASR[166.11].L "sp|P49327|FAS_HUMAN,tr|A0A0U1RQF0|A0A0U1RQF0_HUMAN" 2 3327.7479 0.74 90441 23652 4 3327.759205 832.9442 Fatty acid synthase OS=Homo sapiens OX=9606 GN=FASN PE=1 SV=3 6.93 3603.6 - 1.07E+06 - - - 3.4077 - 5.937 0.667 - 772.1 1 2 0 0.0113 30 0 0 0 3.19E+07 4.33E+07 - - - 5.5735 1 221125_WJC_METTL3_EV_vs_WT_F06.23653.23653.3 4.46E-11 18/140 K.SEGSTPADGLPGEAAEDDLAGAPALSQASSGTC[160.03]FPR.K "sp|Q8IX01|SUGP2_HUMAN,tr|M0R2Z9|M0R2Z9_HUMAN" 2 3488.5638 1.73 90442 23653 3 3488.569124 1163.8619 SURP and G-patch domain-containing protein 2 OS=Homo sapiens OX=9606 GN=SUGP2 PE=1 SV=2 3.71 3603.7 - 404534 - - - 1.5301 - 3.764 0.657 - 141.6 1 2 0 0.0053 36 0 0 0 1.15E+07 6.67E+06 - - - 8.9129 1 221125_WJC_METTL3_EV_vs_WT_F06.23654.23654.3 7.47E-13 16/140 K.SEGSTPADGLPGEAAEDDLAGAPALSQASSGTC[160.03]FPR[166.11].K "sp|Q8IX01|SUGP2_HUMAN,tr|M0R2Z9|M0R2Z9_HUMAN" 2 3498.5721 1.73 90443 23654 3 3499.586216 1167.198 SURP and G-patch domain-containing protein 2 OS=Homo sapiens OX=9606 GN=SUGP2 PE=1 SV=2 3.71 3603.8 - 312800 - - - 289.8783 - 3.472 0.671 - 125.5 1 2 0 1.0142 36 0 0 0 1.15E+07 6.67E+06 - - - 8.6037 0.9999 221125_WJC_METTL3_EV_vs_WT_F06.23660.23660.4 2.61E-06 9/108 R.GLLQDDAHPTLVTYADHSK[136.11].L "sp|Q86U44|MTA70_HUMAN,tr|F5H6D8|F5H6D8_HUMAN,tr|H0YFV6|H0YFV6_HUMAN,tr|B4DTN4|B4DTN4_HUMAN" 4 2088.0367 0.001 90447 23660 4 2088.036722 523.0165 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 5.13 3604.5 - 1.01E+06 - - - -0.0053 - 2.296 0.466 - 68.8 1 2 0 0 19 0 0 0 0.00E+00 1.83E+07 - - - 3.5632 1 221125_WJC_METTL3_EV_vs_WT_F06.23661.23661.4 5.47E-11 33/174 R.LNSVQSSERPLFLVHPIEGSTTVFHSLASR.L "sp|P49327|FAS_HUMAN,tr|A0A0U1RQF0|A0A0U1RQF0_HUMAN" 2 3307.7313 0.76 90448 23661 4 3307.738526 827.9401 Fatty acid synthase OS=Homo sapiens OX=9606 GN=FASN PE=1 SV=3 6.93 3604.6 - 863835 - - - 2.177 - 5.992 0.649 - 691.7 1 2 0 0.0072 30 0 0 0 3.17E+07 4.16E+07 - - - 5.4208 1 221125_WJC_METTL3_EV_vs_WT_F06.23665.23665.3 7.39E-05 23/76 K.K[136.11]QELEVLTANIQDLK[136.11]EEYSR[166.11].K "sp|Q9HBM1|SPC25_HUMAN,tr|C9JW94|C9JW94_HUMAN" 2 2431.2805 2.95 90450 23665 3 2431.286078 811.4341 Kinetochore protein Spc25 OS=Homo sapiens OX=9606 GN=SPC25 PE=1 SV=1 4.59 3605.1 - 541016 - - - 2.2988 - 5.108 0.6 - 761.3 1 2 1 0.0056 20 0 0 0 3.04E+07 1.03E+07 - - - 9.1842 1 221125_WJC_METTL3_EV_vs_WT_F06.23666.23666.4 8.51E-16 28/210 R.LGSDFGSSRPAASLAQPPTPQPPPVNGILVPNGFSK.L sp|Q7Z5L9|I2BP2_HUMAN 1 3599.8736 1.38 90451 23666 4 3599.879721 900.9757 Interferon regulatory factor 2-binding protein 2 OS=Homo sapiens OX=9606 GN=IRF2BP2 PE=1 SV=2 8.75 3605.3 - 1.09E+06 - - - 1.6914 - 4.239 0.659 - 241.2 1 2 0 0.0061 36 0 0 0 1.04E+08 7.51E+07 - - - 5.386 1 221125_WJC_METTL3_EV_vs_WT_F06.23667.23667.2 0.000296 18/32 R.AAVEEGIVLGGGC[160.03]ALLR.C "sp|P10809|CH60_HUMAN,tr|A0A7I2V2X6|A0A7I2V2X6_HUMAN,tr|A0A7I2YQK6|A0A7I2YQK6_HUMAN,tr|A0A7I2V599|A0A7I2V599_HUMAN" 4 1683.8978 1.47 90452 23667 2 1683.901169 842.9562 "60 kDa heat shock protein, mitochondrial OS=Homo sapiens OX=9606 GN=HSPD1 PE=1 SV=2" 4.53 3605.4 - 375765 - - - 2.0061 - 3.601 0.506 - 948.2 1 2 0 0.0034 17 0 0 0 1.22E+07 8.32E+06 - - - 5.9272 0.994 221125_WJC_METTL3_EV_vs_WT_F06.23671.23671.4 0.0983 16/126 R.SGVEK[136.11]DLDEVLQTHSVFVNVSK[136.11].G "sp|Q9Y3A5|SBDS_HUMAN,tr|F8WE72|F8WE72_HUMAN" 2 2445.2722 0.51 90454 23671 4 2445.273707 612.3253 Ribosome maturation protein SBDS OS=Homo sapiens OX=9606 GN=SBDS PE=1 SV=4 4.75 3606 - 952451 - - - 0.6085 - 2.184 0.276 - 83.5 1 2 1 0.0015 22 0 0 0 1.38E+07 2.71E+07 - - - 1.8835 1 221125_WJC_METTL3_EV_vs_WT_F06.23676.23676.3 9.71E-10 26/108 R.QVASHVGLHSASIPGILALDLC[160.03]PSDTNK[136.11].L "sp|Q9UMS4|PRP19_HUMAN,tr|F5GY56|F5GY56_HUMAN" 2 2907.5004 1.66 90457 23676 3 2907.504736 970.1741 Pre-mRNA-processing factor 19 OS=Homo sapiens OX=9606 GN=PRPF19 PE=1 SV=1 5.98 3606.6 - 852175 - - - 1.4941 - 4.314 0.581 - 593.1 1 2 0 0.0043 28 0 0 0 2.08E+07 1.25E+07 - - - 8.3796 0.9995 221125_WJC_METTL3_EV_vs_WT_F06.23679.23679.3 1.57E-05 Oct-60 K.GLDVDSLVIEHIQVNK[136.11].A "sp|P18621|RL17_HUMAN,tr|A0A087WWH0|A0A087WWH0_HUMAN,tr|J3QS96|J3QS96_HUMAN,tr|J3QLC8|J3QLC8_HUMAN,tr|J3QQT2|J3QQT2_HUMAN,tr|A0A0A0MRF8|A0A0A0MRF8_HUMAN,tr|J3KRB3|J3KRB3_HUMAN,tr|J3KRX5|J3KRX5_HUMAN,tr|A0A087WXM6|A0A087WXM6_HUMAN,tr|A0A0A6YYL6|A0A0A6YYL6_HUMAN" 10 1785.9716 0.87 90459 23679 3 1785.978465 596.3311 60S ribosomal protein L17 OS=Homo sapiens OX=9606 GN=RPL17 PE=1 SV=3 4.54 3606.9 - 328077 - - - 3.836 - 2.151 0.452 - 84.2 1 2 0 0.0069 16 0 0 0 5.96E+06 6.88E+06 - - - 5.5427 1 221125_WJC_METTL3_EV_vs_WT_F06.23680.23680.4 3.26E-10 30/156 R.R[166.11]GEQLTLPPPPQLGYSITAEDLDLEK[136.11]K[136.11].A "sp|Q96HA1|P121A_HUMAN,sp|A6NF01|P121B_HUMAN,sp|A8CG34|P121C_HUMAN" 3 3033.6233 1.81 90460 23680 4 3033.631178 759.4131 Nuclear envelope pore membrane protein POM 121 OS=Homo sapiens OX=9606 GN=POM121 PE=1 SV=2 4.51 3607 - 1.24E+06 - - - 2.6012 - 4.738 0.617 - 413.4 1 2 0 0.0079 27 0 0 0 6.87E+07 3.79E+07 - - - 5.0809 1 221125_WJC_METTL3_EV_vs_WT_F06.23685.23685.3 3.05E-06 22/96 K.EQASHLGGAVFSGAGNIAAATGLVK.R "sp|Q16143|SYUB_HUMAN,tr|G4Y816|G4Y816_HUMAN" 2 2325.2077 1.54 90463 23685 3 2325.209321 776.0765 Beta-synuclein OS=Homo sapiens OX=9606 GN=SNCB PE=1 SV=1 6.85 3607.6 - 1.13E+06 - - - 0.6933 - 4.286 0.535 - 363.5 1 2 0 0.0016 25 0 0 0 3.91E+07 2.55E+07 - - - 7.8525 1 221125_WJC_METTL3_EV_vs_WT_F06.23686.23686.3 2.72E-07 17/96 K.EQASHLGGAVFSGAGNIAAATGLVK[136.11].R "sp|Q16143|SYUB_HUMAN,tr|G4Y816|G4Y816_HUMAN" 2 2333.2219 1.54 90464 23686 3 2333.219213 778.7479 Beta-synuclein OS=Homo sapiens OX=9606 GN=SNCB PE=1 SV=1 6.85 3607.7 - 912227 - - - -1.1555 - 3.937 0.527 - 196.3 1 2 0 -0.0027 25 0 0 0 3.91E+07 2.55E+07 - - - 7.5676 1 221125_WJC_METTL3_EV_vs_WT_F06.23691.23691.4 1.97E-11 35/156 R.RGEQLTLPPPPQLGYSITAEDLDLEKK.A "sp|Q96HA1|P121A_HUMAN,sp|A6NF01|P121B_HUMAN,sp|A8CG34|P121C_HUMAN" 3 3007.5866 1.81 90467 23691 4 3007.58953 752.9039 Nuclear envelope pore membrane protein POM 121 OS=Homo sapiens OX=9606 GN=POM121 PE=1 SV=2 4.51 3608.3 - 5.39E+06 - - - 0.9686 - 5.415 0.633 - 696.8 1 2 0 0.0029 27 0 0 0 6.87E+07 3.79E+07 - - - 5.2634 0.9999 221125_WJC_METTL3_EV_vs_WT_F06.23692.23692.4 5.60E-08 19/126 R.SGVEKDLDEVLQTHSVFVNVSK.G "sp|Q9Y3A5|SBDS_HUMAN,tr|F8WE72|F8WE72_HUMAN" 2 2429.2438 0.49 90468 23692 4 2429.247291 608.3182 Ribosome maturation protein SBDS OS=Homo sapiens OX=9606 GN=SBDS PE=1 SV=4 4.75 3608.5 - 1.46E+06 - - - 1.4293 - 4.445 0.541 - 307.6 1 2 1 0.0035 22 0 0 0 1.39E+07 2.84E+07 - - - 4.422 1 221125_WJC_METTL3_EV_vs_WT_F06.23693.23693.3 2.08E-08 24/72 K.IIAATIENAQPILQIDNAR.L sp|P08779|K1C16_HUMAN 1 2063.1375 84.64 90469 23693 3 2063.140045 688.7198 "Keratin, type I cytoskeletal 16 OS=Homo sapiens OX=9606 GN=KRT16 PE=1 SV=4" 4.37 3608.6 - 983574 - - - 1.2316 - 4.014 0.603 - 669.3 1 2 0 0.0025 19 0 0 0 2.90E+07 3.43E+05 - - - 8.6766 1 221125_WJC_METTL3_EV_vs_WT_F06.23694.23694.3 2.07E-09 22/140 R.LGSDFGSSRPAASLAQPPTPQPPPVNGILVPNGFSK.L sp|Q7Z5L9|I2BP2_HUMAN 1 3599.8736 2.12 90470 23694 3 3599.875142 1200.9652 Interferon regulatory factor 2-binding protein 2 OS=Homo sapiens OX=9606 GN=IRF2BP2 PE=1 SV=2 8.75 3608.7 - 709299 - - - 0.4195 - 3.328 0.648 - 235.9 1 2 0 0.0015 36 0 0 0 4.20E+07 1.98E+07 - - - 8.5304 0.9998 221125_WJC_METTL3_EV_vs_WT_F06.23695.23695.2 0.0118 16-Sep R.DAETWFLSK.T "sp|P08779|K1C16_HUMAN,tr|K7ENW6|K7ENW6_HUMAN" 2 1095.5237 4.36 90471 23695 2 1095.522889 548.7691 "Keratin, type I cytoskeletal 16 OS=Homo sapiens OX=9606 GN=KRT16 PE=1 SV=4" 4.37 3608.9 - 392534 - - - -0.7184 - 2.013 0.446 - 310.6 1 2 0 -0.0008 9 0 0 0 7.27E+06 1.67E+06 - - - 4.359 0.9771 221125_WJC_METTL3_EV_vs_WT_F06.23700.23700.3 6.16E-07 16/92 K.EK[136.11]K[136.11]EEQVISLGPQVAEGENVFGVC[160.03].H "sp|P62263|RS14_HUMAN,tr|A0A2R8Y811|A0A2R8Y811_HUMAN,tr|E5RH77|E5RH77_HUMAN" 3 2661.3291 1.68 90473 23700 3 2661.328726 888.117 40S ribosomal protein S14 OS=Homo sapiens OX=9606 GN=RPS14 PE=1 SV=3 4.33 3609.5 - 2.66E+06 - - - -0.1341 - 2.97 0.437 - 191.7 1 1 1 -0.0004 24 0 0 0 1.29E+08 7.71E+07 - - - 5.9403 0.9079 221125_WJC_METTL3_EV_vs_WT_F06.23701.23701.3 8.66E-11 17/156 L.SLLSVPQLSGAGGGGGEAGAGGGAAAVAAGGVVTTTASGK[136.11].R "sp|P56270|MAZ_HUMAN,tr|A0A087WWR2|A0A087WWR2_HUMAN" 2 3275.6837 1.15 90474 23701 3 3276.693245 1092.9018 Myc-associated zinc finger protein OS=Homo sapiens OX=9606 GN=MAZ PE=1 SV=1 5.72 3609.6 - 894264 - - - 308.19 - 3.346 0.551 - 142.2 1 1 0 1.0095 40 0 0 0 2.27E+07 1.98E+07 - - - 7.1821 1 221125_WJC_METTL3_EV_vs_WT_F06.23704.23704.3 1.92E-14 25/156 L.SLLSVPQLSGAGGGGGEAGAGGGAAAVAAGGVVTTTASGK.R "sp|P56270|MAZ_HUMAN,tr|A0A087WWR2|A0A087WWR2_HUMAN" 2 3267.6695 1.15 90477 23704 3 3267.673988 1090.2304 Myc-associated zinc finger protein OS=Homo sapiens OX=9606 GN=MAZ PE=1 SV=1 5.72 3610 - 1.19E+06 - - - 1.3698 - 4.115 0.718 - 374.2 1 1 0 0.0045 40 0 0 0 2.27E+07 1.98E+07 - - - 9.7983 1 221125_WJC_METTL3_EV_vs_WT_F06.23705.23705.3 3.29E-09 20/84 K.DTTLFDLSQFGSSNTSHENLQK.T "sp|P20585|MSH3_HUMAN,tr|A0A590UJN8|A0A590UJN8_HUMAN,tr|A0A590UKC9|A0A590UKC9_HUMAN,tr|A0A590UJW0|A0A590UJW0_HUMAN" 4 2468.1456 0.56 90478 23705 3 2468.147367 823.7225 DNA mismatch repair protein Msh3 OS=Homo sapiens OX=9606 GN=MSH3 PE=1 SV=4 4.54 3610.1 - 864758 - - - 0.7313 - 4.126 0.629 - 295.4 1 2 0 0.0018 22 0 0 0 9.80E+06 1.76E+07 - - - 8.9124 0.9996 221125_WJC_METTL3_EV_vs_WT_F06.23712.23712.4 2.34E-05 18/132 R.ISVAGVTSSNVGYLAHAIHQVTK[136.11].- sp|P00505|AATM_HUMAN 1 2359.2739 1.19 90483 23712 4 2359.280392 590.8258 "Aspartate aminotransferase, mitochondrial OS=Homo sapiens OX=9606 GN=GOT2 PE=1 SV=3" 8.61 3611 - 1.00E+06 - - - 2.733 - 3.79 0.378 - 225.4 1 2 0 0.0064 23 0 0 0 1.25E+07 1.05E+07 - - - 2.946 0.9998 221125_WJC_METTL3_EV_vs_WT_F06.23720.23720.4 1.76E-05 19/162 K.EGSVVVDLAAEAGGNFETTKPGELYIHK.G "sp|Q13423|NNTM_HUMAN,tr|E9PCX7|E9PCX7_HUMAN,tr|A0A590UK15|A0A590UK15_HUMAN,tr|A0A590UJM2|A0A590UJM2_HUMAN,tr|A0A590UK29|A0A590UK29_HUMAN,tr|A0A590UJI3|A0A590UJI3_HUMAN" 6 2930.4662 0.83 90489 23720 4 2930.471486 733.6238 "NAD(P) transhydrogenase, mitochondrial OS=Homo sapiens OX=9606 GN=NNT PE=1 SV=3" 4.57 3612 - 862113 - - - 1.8147 - 3.581 0.386 - 148.1 1 2 0 0.0053 28 0 0 0 8.48E+06 1.03E+07 - - - 2.9803 1 221125_WJC_METTL3_EV_vs_WT_F06.23721.23721.3 1.04E-10 24/108 K.NLESSTGFQIPSQELASQIDPQKDIEPR.T sp|Q9Y2X9|ZN281_HUMAN 1 3126.5469 1.67 90490 23721 3 3126.559156 1043.1896 Zinc finger protein 281 OS=Homo sapiens OX=9606 GN=ZNF281 PE=1 SV=1 4.18 3612.2 - 755156 - - - 3.9081 - 5.048 0.662 - 400.3 1 2 1 0.0122 28 0 0 0 1.77E+08 1.06E+08 - - - 9.642 0.98 221125_WJC_METTL3_EV_vs_WT_F06.23726.23726.3 8.63E-05 15/92 R.NGPGFHNDIDSNSTIQEILIPASK[136.11].V sp|Q96I24|FUBP3_HUMAN 1 2574.2805 2.52 90492 23726 3 2575.267203 859.1008 Far upstream element-binding protein 3 OS=Homo sapiens OX=9606 GN=FUBP3 PE=1 SV=2 4.54 3612.8 - 1.47E+06 - - - 383.2749 - 2.897 0.602 - 124.7 1 2 0 0.9867 24 0 0 0 8.87E+06 3.52E+06 - - - 7.4489 0.9989 221125_WJC_METTL3_EV_vs_WT_F06.23728.23728.4 0.00794 17/186 K.QTIGNSC[160.03]GTIGLIHAVANNQDK[136.11]LGFEDGSVLK[136.11].Q "sp|P09936|UCHL1_HUMAN,tr|D6R956|D6R956_HUMAN,tr|D6RE83|D6RE83_HUMAN,tr|D6R974|D6R974_HUMAN" 4 3371.7115 0.57 90494 23728 4 3371.722141 843.9351 Ubiquitin carboxyl-terminal hydrolase isozyme L1 OS=Homo sapiens OX=9606 GN=UCHL1 PE=1 SV=2 5.38 3613.1 - 1.02E+06 - - - 3.1696 - 3.531 0.432 - 130.9 1 2 1 0.0107 32 0 0 0 7.98E+06 1.39E+07 - - - 3.3641 1 221125_WJC_METTL3_EV_vs_WT_F06.23730.23730.3 3.75E-12 26/120 R.KYTLPPGVDPTQVSSSLSPEGTLTVEAPMPK.L "sp|P04792|HSPB1_HUMAN,tr|A0A6Q8PGK1|A0A6Q8PGK1_HUMAN" 2 3225.6479 3.17 90496 23730 3 3225.657702 1076.2232 Heat shock protein beta-1 OS=Homo sapiens OX=9606 GN=HSPB1 PE=1 SV=2 4.68 3613.3 - 699346 - - - 3.0397 - 5.593 0.677 - 492.1 1 2 0 0.0098 31 0 0 0 3.61E+07 1.14E+07 - - - 10.0458 0.998 221125_WJC_METTL3_EV_vs_WT_F06.23731.23731.4 1.36E-08 18/186 K.QTIGNSC[160.03]GTIGLIHAVANNQDKLGFEDGSVLK.Q "sp|P09936|UCHL1_HUMAN,tr|D6R956|D6R956_HUMAN,tr|D6RE83|D6RE83_HUMAN,tr|D6R974|D6R974_HUMAN" 4 3355.6831 0.57 90497 23731 4 3355.700765 839.928 Ubiquitin carboxyl-terminal hydrolase isozyme L1 OS=Homo sapiens OX=9606 GN=UCHL1 PE=1 SV=2 5.38 3613.5 - 666071 - - - 5.2779 - 3.95 0.505 - 132.5 1 2 1 0.0177 32 0 0 0 7.98E+06 1.39E+07 - - - 4.0314 1 221125_WJC_METTL3_EV_vs_WT_F06.23735.23735.3 1.38E-14 32/108 K.NLESSTGFQIPSQELASQIDPQK[136.11]DIEPR[166.11].T sp|Q9Y2X9|ZN281_HUMAN 1 3144.5694 1.66 90499 23735 3 3144.570636 1049.1971 Zinc finger protein 281 OS=Homo sapiens OX=9606 GN=ZNF281 PE=1 SV=1 4.18 3614 - 1.48E+06 - - - 0.3908 - 5.554 0.672 - 790 1 2 1 0.0012 28 0 0 0 1.76E+08 1.06E+08 - - - 9.9763 1 221125_WJC_METTL3_EV_vs_WT_F06.23740.23740.4 3.72E-11 29/162 K.NLESSTGFQIPSQELASQIDPQKDIEPR.T sp|Q9Y2X9|ZN281_HUMAN 1 3126.5469 1.12 90504 23740 4 3126.55571 782.644 Zinc finger protein 281 OS=Homo sapiens OX=9606 GN=ZNF281 PE=1 SV=1 4.18 3614.6 - 854085 - - - 2.806 - 5.432 0.616 - 487 1 2 1 0.0088 28 0 0 0 4.50E+07 4.03E+07 - - - 5.1107 0.9999 221125_WJC_METTL3_EV_vs_WT_F06.23743.23743.4 2.42E-05 11/102 K.TEAEIAHIALETLEGHQR.A "sp|O75955|FLOT1_HUMAN,tr|A2AB10|A2AB10_HUMAN,tr|A0A140T910|A0A140T910_HUMAN,tr|A2AB09|A2AB09_HUMAN,tr|A2AB11|A2AB11_HUMAN,tr|A0A140T9C3|A0A140T9C3_HUMAN,tr|A0A140T9R1|A0A140T9R1_HUMAN,tr|A0A140T957|A0A140T957_HUMAN,tr|A0A140T9B1|A0A140T9B1_HUMAN,tr|A0A140T959|A0A140T959_HUMAN,tr|A2AB12|A2AB12_HUMAN,tr|A0A0G2JJQ6|A0A0G2JJQ6_HUMAN,tr|A0A140T9X0|A0A140T9X0_HUMAN,tr|A2AB13|A2AB13_HUMAN" 14 2017.0229 1.84 90507 23743 4 2017.026814 505.263 Flotillin-1 OS=Homo sapiens OX=9606 GN=FLOT1 PE=1 SV=3 4.87 3615 - 206574 - - - 1.9563 - 2.068 0.475 - 52.9 1 2 0 0.0039 18 0 0 0 1.45E+06 7.89E+05 - - - 3.6082 1 221125_WJC_METTL3_EV_vs_WT_F06.23757.23757.4 4.84E-14 35/210 R.LGSDFGSSR[166.11]PAASLAQPPTPQPPPVNGILVPNGFSK[136.11].L sp|Q7Z5L9|I2BP2_HUMAN 1 3617.8961 1.37 90517 23757 4 3617.897804 905.4813 Interferon regulatory factor 2-binding protein 2 OS=Homo sapiens OX=9606 GN=IRF2BP2 PE=1 SV=2 8.75 3616.8 - 1.96E+06 - - - 0.4704 - 4.349 0.635 - 406.4 1 2 0 0.0017 36 0 0 0 1.04E+08 7.56E+07 - - - 5.1859 1 221125_WJC_METTL3_EV_vs_WT_F06.23758.23758.4 7.09E-09 29/162 K.NLESSTGFQIPSQELASQIDPQK[136.11]DIEPR[166.11].T sp|Q9Y2X9|ZN281_HUMAN 1 3144.5694 1.27 90518 23758 4 3144.577754 787.1496 Zinc finger protein 281 OS=Homo sapiens OX=9606 GN=ZNF281 PE=1 SV=1 4.18 3616.9 - 1.24E+06 - - - 2.6544 - 4.449 0.623 - 380.9 1 2 1 0.0083 28 0 0 0 4.35E+07 3.44E+07 - - - 5.1097 0.9999 221125_WJC_METTL3_EV_vs_WT_F06.23760.23760.4 2.16E-06 17/198 R.R[166.11]VYATILNAGTNTDGFK[136.11]EQGVTFPSGDIQEQLIR[166.11].S "sp|P49327|FAS_HUMAN,tr|A0A0U1RQF0|A0A0U1RQF0_HUMAN" 2 3765.932 0.2 90520 23760 4 3765.928865 942.4903 Fatty acid synthase OS=Homo sapiens OX=9606 GN=FASN PE=1 SV=3 4.78 3617.2 - 555827 - - - -0.8439 - 2.497 0.54 - 65.6 1 2 1 -0.0032 34 0 0 0 3.75E+06 1.88E+07 - - - 4.1982 1 221125_WJC_METTL3_EV_vs_WT_F06.23763.23763.4 1.60E-15 26/168 K.K[136.11]LGVNNISGIEEVNMFTNQGTVIHFNNPK[136.11].V "sp|P20290|BTF3_HUMAN,tr|A0A7I2V3T6|A0A7I2V3T6_HUMAN,tr|A0A7I2YQL2|A0A7I2YQL2_HUMAN" 3 3229.6525 0.85 90521 23763 4 3229.655362 808.4204 Transcription factor BTF3 OS=Homo sapiens OX=9606 GN=BTF3 PE=1 SV=1 6.76 3617.6 - 2.61E+06 - - - 0.8917 - 4.895 0.664 - 569.7 1 2 0 0.0029 29 0 0 0 1.59E+08 1.87E+08 - - - 5.4941 1 221125_WJC_METTL3_EV_vs_WT_F06.23764.23764.4 1.59E-15 33/168 K.KLGVNNISGIEEVNMFTNQGTVIHFNNPK.V "sp|P20290|BTF3_HUMAN,tr|A0A7I2V3T6|A0A7I2V3T6_HUMAN,tr|A0A7I2YQL2|A0A7I2YQL2_HUMAN" 3 3213.6241 0.85 90522 23764 4 3213.629978 804.4133 Transcription factor BTF3 OS=Homo sapiens OX=9606 GN=BTF3 PE=1 SV=1 6.76 3617.6 - 2.89E+06 - - - 1.8347 - 5.495 0.67 - 761.4 1 2 0 0.0059 29 0 0 0 1.59E+08 1.86E+08 - - - 5.5811 0.9714 221125_WJC_METTL3_EV_vs_WT_F06.23765.23765.4 0.00174 16/102 R.K[136.11]IELFGR[166.11]PHNVQPNWITL.G sp|Q86U44|MTA70_HUMAN 1 2179.2021 0.02 90523 23765 4 2179.203754 545.8078 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 8.75 3617.8 - 1.52E+06 - - - 0.753 - 2.86 0.358 - 124.2 1 1 0 0.0016 18 0 0 0 6.44E+06 4.26E+08 - - - 2.7015 1 221125_WJC_METTL3_EV_vs_WT_F06.23774.23774.3 2.47E-09 19/52 K.SNSFFEGVDWEHIR.E sp|Q15208|STK38_HUMAN 1 1721.7798 195 90529 23774 3 1721.779044 574.9339 Serine\threonine-protein kinase 38 OS=Homo sapiens OX=9606 GN=STK38 PE=1 SV=1 4.65 3618.9 - 689991 - - - -0.4298 - 3.435 0.677 - 550.8 1 2 0 -0.0007 14 0 0 0 2.10E+07 1.08E+05 - - - 9.3671 0.9997 221125_WJC_METTL3_EV_vs_WT_F06.23781.23781.4 7.80E-09 18/150 K.SQELNFVMDVNSSK[136.11]YPSLLLHSQEEK[136.11].T "sp|Q8IWZ3|ANKH1_HUMAN,tr|H0Y472|H0Y472_HUMAN,tr|H0Y7Y3|H0Y7Y3_HUMAN,tr|H0Y4P6|H0Y4P6_HUMAN,tr|H0Y785|H0Y785_HUMAN" 5 3037.5038 1.4 90533 23781 4 3037.494216 760.3832 Ankyrin repeat and KH domain-containing protein 1 OS=Homo sapiens OX=9606 GN=ANKHD1 PE=1 SV=1 4.83 3619.7 - 691732 - - - -3.1394 - 3.609 0.555 - 129.4 1 2 1 -0.0095 26 0 0 0 3.79E+07 2.71E+07 - - - 4.4589 1 221125_WJC_METTL3_EV_vs_WT_F06.23782.23782.3 6.05E-09 19/140 Y.GGASGVGSGLGLGGGSSYSYGSGLGIGGGFSSSSGR.A sp|P48668|K2C6C_HUMAN 1 3052.4122 999 90534 23782 3 3052.409149 1018.478 "Keratin, type II cytoskeletal 6C OS=Homo sapiens OX=9606 GN=KRT6C PE=1 SV=3" 8.59 3619.9 - 954183 - - - -1.011 - 4.084 0.656 - 121.8 1 1 0 -0.0031 36 0 0 0 5.47E+06 0.00E+00 - - - 9.0901 0.9999 221125_WJC_METTL3_EV_vs_WT_F06.23786.23786.3 1.53E-11 20/92 R.VETGVLK[136.11]PGMVVTFAPVNVTTEVK[136.11].S "sp|P68104|EF1A1_HUMAN,sp|Q5VTE0|EF1A3_HUMAN,tr|A0A7I2V659|A0A7I2V659_HUMAN,tr|A0A7I2V3H3|A0A7I2V3H3_HUMAN,tr|A0A7I2V5N4|A0A7I2V5N4_HUMAN,tr|A0A087WVQ9|A0A087WVQ9_HUMAN" 6 2530.4051 0.26 90536 23786 3 2530.396371 844.4757 Elongation factor 1-alpha 1 OS=Homo sapiens OX=9606 GN=EEF1A1 PE=1 SV=1 6.11 3620.4 - 1.22E+06 - - - -3.4686 - 3.885 0.593 - 290.7 1 2 0 -0.0088 24 0 0 0 1.34E+07 5.25E+07 - - - 8.301 0.9992 221125_WJC_METTL3_EV_vs_WT_F06.23791.23791.2 0.00321 22-Aug R.VFIGNLNTLVVK[136.11].K "sp|P0DMR1|HNRC4_HUMAN,sp|P07910|HNRPC_HUMAN,sp|O60812|HNRC1_HUMAN,sp|B2RXH8|HNRC2_HUMAN,sp|B7ZW38|HNRC3_HUMAN,tr|G3V251|G3V251_HUMAN,tr|B4DY08|B4DY08_HUMAN,tr|G3V575|G3V575_HUMAN,tr|B4DSU6|B4DSU6_HUMAN,tr|G3V3K6|G3V3K6_HUMAN,tr|B2R5W2|B2R5W2_HUMAN,tr|G3V4C1|G3V4C1_HUMAN,tr|A0A0G2JPF8|A0A0G2JPF8_HUMAN,tr|A0A0G2JNQ3|A0A0G2JNQ3_HUMAN,tr|G3V576|G3V576_HUMAN,tr|G3V5X6|G3V5X6_HUMAN,tr|G3V2H6|G3V2H6_HUMAN,tr|G3V4W0|G3V4W0_HUMAN,tr|G3V555|G3V555_HUMAN,tr|G3V4M8|G3V4M8_HUMAN,tr|G3V2Q1|G3V2Q1_HUMAN" 21 1323.8006 0.81 90539 23791 2 1323.798226 662.9076 Heterogeneous nuclear ribonucleoprotein C-like 4 OS=Homo sapiens OX=9606 GN=HNRNPCL4 PE=3 SV=1 8.72 3621.1 - 396752 - - - -1.7729 - 1.535 0.401 - 119.9 1 2 0 -0.0023 12 0 0 0 7.56E+06 9.34E+06 - - - 3.1296 0.9999 221125_WJC_METTL3_EV_vs_WT_F06.23795.23795.4 1.78E-09 23/150 K.SQELNFVMDVNSSKYPSLLLHSQEEK.T "sp|Q8IWZ3|ANKH1_HUMAN,tr|H0Y472|H0Y472_HUMAN,tr|H0Y7Y3|H0Y7Y3_HUMAN,tr|H0Y4P6|H0Y4P6_HUMAN,tr|H0Y785|H0Y785_HUMAN" 5 3021.4754 1.4 90542 23795 4 3021.477076 756.3761 Ankyrin repeat and KH domain-containing protein 1 OS=Homo sapiens OX=9606 GN=ANKHD1 PE=1 SV=1 4.83 3621.5 - 1.41E+06 - - - 0.5706 - 3.849 0.618 - 261.2 1 2 1 0.0017 26 0 0 0 3.69E+07 2.63E+07 - - - 5.0297 0.9999 221125_WJC_METTL3_EV_vs_WT_F06.23799.23799.4 1.07E-10 21/114 K.R[166.11]IQEIIEQLDVTTSEYEK[136.11]EK[136.11].L "sp|P10809|CH60_HUMAN,tr|A0A7I2V2X6|A0A7I2V2X6_HUMAN,tr|A0A7I2YQK6|A0A7I2YQK6_HUMAN,tr|A0A7I2V599|A0A7I2V599_HUMAN" 4 2476.2907 1.27 90544 23799 4 2476.292508 620.08 "60 kDa heat shock protein, mitochondrial OS=Homo sapiens OX=9606 GN=HSPD1 PE=1 SV=2" 4.42 3622.1 - 714053 - - - 0.722 - 3.61 0.612 - 277.9 1 2 1 0.0018 20 0 0 0 7.15E+08 5.61E+08 - - - 4.9815 0.9903 221125_WJC_METTL3_EV_vs_WT_F06.23800.23800.4 0.0871 10/132 R.SFTPHQQAHIPNSIMTILEASGK[136.11].Q sp|Q92797|SYMPK_HUMAN 1 2514.278 0.86 90545 23800 4 2514.282076 629.5768 Symplekin OS=Homo sapiens OX=9606 GN=SYMPK PE=1 SV=2 6.66 3622.2 - 261505 - - - 1.604 - 2.368 0.201 - 61.1 1 2 0 0.004 23 0 0 0 9.69E+06 1.13E+07 - - - 1.2537 1 221125_WJC_METTL3_EV_vs_WT_F06.23803.23803.3 3.00E-08 19/124 R.GGGGSFGYSYGGGSGGGFSASSLGGGFGGGSR.G sp|P35527|K1C9_HUMAN 1 2704.1538 1.18 90546 23803 3 2704.155897 902.3919 "Keratin, type I cytoskeletal 9 OS=Homo sapiens OX=9606 GN=KRT9 PE=1 SV=3" 8.59 3622.6 - 801689 - - - 0.7625 - 3.273 0.697 - 211.2 1 2 0 0.0021 32 0 0 0 4.58E+07 3.89E+07 - - - 9.0382 1 221125_WJC_METTL3_EV_vs_WT_F06.23805.23805.3 1.79E-11 28/76 K.R[166.11]IQEIIEQLDVTTSEYEK[136.11]EK[136.11].L "sp|P10809|CH60_HUMAN,tr|A0A7I2V2X6|A0A7I2V2X6_HUMAN,tr|A0A7I2YQK6|A0A7I2YQK6_HUMAN,tr|A0A7I2V599|A0A7I2V599_HUMAN" 4 2476.2907 1.3 90547 23805 3 2476.286757 826.4375 "60 kDa heat shock protein, mitochondrial OS=Homo sapiens OX=9606 GN=HSPD1 PE=1 SV=2" 4.42 3622.8 - 2.14E+06 - - - -1.6004 - 4.837 0.679 - 1133.5 1 2 1 -0.004 20 0 0 0 1.44E+09 1.10E+09 - - - 9.9332 0.9928 221125_WJC_METTL3_EV_vs_WT_F06.23806.23806.3 3.01E-05 13/84 L.C[160.03]LAISTPDAPATQDGVESLLQK[136.11].F "sp|Q86U44|MTA70_HUMAN,tr|B4E349|B4E349_HUMAN,tr|F5H6D8|F5H6D8_HUMAN,tr|H0YFV6|H0YFV6_HUMAN,tr|B4DTN4|B4DTN4_HUMAN" 5 2321.1664 0.01 90548 23806 3 2321.169177 774.7294 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 4.03 3622.9 - 462658 - - - 1.1847 - 2.845 0.425 - 155.7 1 1 0 0.0027 22 0 0 0 2.39E+05 1.93E+07 - - - 5.7564 0.9887 221125_WJC_METTL3_EV_vs_WT_F06.23811.23811.3 0.00193 13/68 R.K[136.11]IELFGR[166.11]PHNVQPNWITL.G sp|Q86U44|MTA70_HUMAN 1 2179.2021 0 90551 23811 3 2179.200929 727.408 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 8.75 3623.5 - 5.47E+06 - - - -0.5433 - 2.35 0.399 - 143.1 1 1 0 -0.0012 18 0 0 0 6.19E+04 2.80E+08 - - - 5.1157 1 221125_WJC_METTL3_EV_vs_WT_F06.23812.23812.3 2.37E-12 22/92 R.NNQLDPTSK[136.11]EDFLNIC[160.03]IEPDTISK[136.11].G "sp|Q53H12|AGK_HUMAN,tr|E9PC15|E9PC15_HUMAN,tr|A0A3B3ITD0|A0A3B3ITD0_HUMAN,tr|A0A3B3ISY9|A0A3B3ISY9_HUMAN,tr|A0A0G2JLG5|A0A0G2JLG5_HUMAN,tr|A0A3B3ISZ0|A0A3B3ISZ0_HUMAN" 6 2806.3666 1.21 90552 23812 3 2806.368512 936.4628 "Acylglycerol kinase, mitochondrial OS=Homo sapiens OX=9606 GN=AGK PE=1 SV=2" 4.11 3623.7 - 1.08E+06 - - - 0.6849 - 4.145 0.652 - 380.5 1 2 1 0.0019 24 0 0 0 4.98E+07 4.12E+07 - - - 9.1111 1 221125_WJC_METTL3_EV_vs_WT_F06.23813.23813.3 0.000229 31/76 K.RIQEIIEQLDVTTSEYEKEK.L "sp|P10809|CH60_HUMAN,tr|A0A7I2V2X6|A0A7I2V2X6_HUMAN,tr|A0A7I2YQK6|A0A7I2YQK6_HUMAN,tr|A0A7I2V599|A0A7I2V599_HUMAN" 4 2450.2541 1.3 90553 23813 3 2450.253878 817.7586 "60 kDa heat shock protein, mitochondrial OS=Homo sapiens OX=9606 GN=HSPD1 PE=1 SV=2" 4.42 3623.7 - 2.72E+06 - - - -0.0702 - 5.111 0.524 - 1548.4 1 2 1 -0.0002 20 0 0 0 1.43E+09 1.10E+09 - - - 8.3398 1 221125_WJC_METTL3_EV_vs_WT_F06.23814.23814.4 7.84E-08 30/114 K.RIQEIIEQLDVTTSEYEKEK.L "sp|P10809|CH60_HUMAN,tr|A0A7I2V2X6|A0A7I2V2X6_HUMAN,tr|A0A7I2YQK6|A0A7I2YQK6_HUMAN,tr|A0A7I2V599|A0A7I2V599_HUMAN" 4 2450.2541 1.27 90554 23814 4 2450.255293 613.5708 "60 kDa heat shock protein, mitochondrial OS=Homo sapiens OX=9606 GN=HSPD1 PE=1 SV=2" 4.42 3623.9 - 1.77E+06 - - - 0.5073 - 4.408 0.614 - 687.4 1 2 1 0.0012 20 0 0 0 7.14E+08 5.61E+08 - - - 5.0658 1 221125_WJC_METTL3_EV_vs_WT_F06.23815.23815.3 5.13E-11 22/112 K.K[136.11]LGVNNISGIEEVNMFTNQGTVIHFNNPK[136.11].V "sp|P20290|BTF3_HUMAN,tr|A0A7I2V3T6|A0A7I2V3T6_HUMAN,tr|A0A7I2YQL2|A0A7I2YQL2_HUMAN" 3 3229.6525 0.52 90555 23815 3 3229.654655 1077.5581 Transcription factor BTF3 OS=Homo sapiens OX=9606 GN=BTF3 PE=1 SV=1 6.76 3624 - 545335 - - - 0.6728 - 5.048 0.729 - 458.4 1 2 0 0.0022 29 0 0 0 8.16E+06 1.57E+07 - - - 10.3917 1 221125_WJC_METTL3_EV_vs_WT_F06.23818.23818.3 8.02E-10 18/92 R.VETGVLKPGMVVTFAPVNVTTEVK.S "sp|P68104|EF1A1_HUMAN,sp|Q5VTE0|EF1A3_HUMAN,tr|A0A7I2V659|A0A7I2V659_HUMAN,tr|A0A7I2V3H3|A0A7I2V3H3_HUMAN,tr|A0A7I2V5N4|A0A7I2V5N4_HUMAN,tr|A0A087WVQ9|A0A087WVQ9_HUMAN" 6 2514.3767 0.26 90556 23818 3 2514.375546 839.1329 Elongation factor 1-alpha 1 OS=Homo sapiens OX=9606 GN=EEF1A1 PE=1 SV=1 6.11 3624.4 - 621196 - - - -0.4781 - 3.671 0.56 - 266.4 1 2 0 -0.0012 24 0 0 0 1.34E+07 5.25E+07 - - - 7.8036 0.9172 221125_WJC_METTL3_EV_vs_WT_F06.23820.23820.3 1.03E-05 13/84 R.TTQPSINESESDPFEVVR[166.11]DDFK[136.11].S "sp|Q76FK4|NOL8_HUMAN,tr|F5GWN9|F5GWN9_HUMAN,tr|F5H101|F5H101_HUMAN,tr|F8WE42|F8WE42_HUMAN" 4 2557.1939 0.66 90558 23820 3 2558.209194 853.4052 Nucleolar protein 8 OS=Homo sapiens OX=9606 GN=NOL8 PE=1 SV=1 4.02 3624.6 - 494667 - - - 397.0297 - 2.45 0.491 - 134.4 1 2 1 1.0153 22 0 0 0 6.13E+06 9.35E+06 - - - 5.8574 1 221125_WJC_METTL3_EV_vs_WT_F06.23838.23838.3 5.30E-13 13/120 K.TLPEPVGTQVSMEEIQNESAC[160.03]GLDVGEC[160.03]ENR.A "sp|Q9ULV3|CIZ1_HUMAN,tr|Q5SYW2|Q5SYW2_HUMAN,tr|F5H2X7|F5H2X7_HUMAN,tr|H0Y5D5|H0Y5D5_HUMAN,tr|A0A494C0L7|A0A494C0L7_HUMAN,tr|Q9BTG3|Q9BTG3_HUMAN" 6 3447.5228 6.36 90569 23838 3 3447.521772 1150.1816 Cip1-interacting zinc finger protein OS=Homo sapiens OX=9606 GN=CIZ1 PE=1 SV=2 3.77 3626.9 - 357783 - - - -0.3127 - 2.934 0.735 - 109.2 1 2 0 -0.0011 31 0 0 0 2.00E+07 3.14E+06 - - - 9.2106 0.9953 221125_WJC_METTL3_EV_vs_WT_F06.23845.23845.4 5.17E-07 22/216 R.GAGFNQNNGAGSENFGLGVVPVSASPSSVEVHPVLEK.L "sp|Q7Z739|YTHD3_HUMAN,tr|A0A087X0Q1|A0A087X0Q1_HUMAN,tr|A0A024R7W5|A0A024R7W5_HUMAN,tr|A0A087WY31|A0A087WY31_HUMAN" 4 3650.7965 11.89 90573 23845 4 3651.784783 913.7064 YTH domain-containing family protein 3 OS=Homo sapiens OX=9606 GN=YTHDF3 PE=1 SV=1 4.75 3627.8 - 1.31E+06 - - - 270.7023 - 3.639 0.579 - 150.8 1 2 0 0.9883 37 0 0 0 8.42E+06 7.08E+05 - - - 4.3705 1 221125_WJC_METTL3_EV_vs_WT_F06.23848.23848.4 3.40E-13 22/174 R.TTGIVMDSGDGVTHTVPIYEGYALPHAILR.L "sp|P63261|ACTG_HUMAN,sp|P60709|ACTB_HUMAN,tr|A0A804GS07|A0A804GS07_HUMAN,tr|I3L3I0|I3L3I0_HUMAN,tr|E7EVS6|E7EVS6_HUMAN,tr|A0A6Q8PFE4|A0A6Q8PFE4_HUMAN,tr|I3L1U9|I3L1U9_HUMAN,tr|A0A2R8YEA7|A0A2R8YEA7_HUMAN,tr|A0A2R8Y793|A0A2R8Y793_HUMAN,tr|I3L4N8|I3L4N8_HUMAN" 10 3182.607 1.01 90576 23848 4 3182.608859 796.659 "Actin, cytoplasmic 2 OS=Homo sapiens OX=9606 GN=ACTG1 PE=1 SV=1" 5.2 3628.1 - 1.23E+06 - - - 0.5731 - 3.617 0.656 - 176.6 1 2 0 0.0018 30 0 0 0 5.10E+07 5.06E+07 - - - 5.3287 1 221125_WJC_METTL3_EV_vs_WT_F06.23853.23853.4 2.96E-12 22/174 R.TTGIVMDSGDGVTHTVPIYEGYALPHAILR[166.11].L "sp|P63261|ACTG_HUMAN,sp|P60709|ACTB_HUMAN,tr|A0A804GS07|A0A804GS07_HUMAN,tr|I3L3I0|I3L3I0_HUMAN,tr|E7EVS6|E7EVS6_HUMAN,tr|A0A6Q8PFE4|A0A6Q8PFE4_HUMAN,tr|I3L1U9|I3L1U9_HUMAN,tr|A0A2R8YEA7|A0A2R8YEA7_HUMAN,tr|A0A2R8Y793|A0A2R8Y793_HUMAN,tr|I3L4N8|I3L4N8_HUMAN" 10 3192.6153 1.01 90578 23853 4 3192.620385 799.1611 "Actin, cytoplasmic 2 OS=Homo sapiens OX=9606 GN=ACTG1 PE=1 SV=1" 5.2 3628.8 - 1.60E+06 - - - 1.5912 - 4.111 0.681 - 195.3 1 2 0 0.0051 30 0 0 0 5.10E+07 5.06E+07 - - - 5.5846 1 221125_WJC_METTL3_EV_vs_WT_F06.23863.23863.4 7.62E-05 26/156 K.NLNLNAALHPDEINIEILNDSHTPGTK.V sp|Q9Y5T5|UBP16_HUMAN 1 2952.4941 1.89 90585 23863 4 2952.501727 739.1308 Ubiquitin carboxyl-terminal hydrolase 16 OS=Homo sapiens OX=9606 GN=USP16 PE=1 SV=1 4.72 3630.1 - 985786 - - - 2.5785 - 4.61 0.573 - 373.9 1 2 0 0.0076 27 0 0 0 3.34E+07 1.77E+07 - - - 4.6895 0.9999 221125_WJC_METTL3_EV_vs_WT_F06.23873.23873.3 8.16E-10 15/92 R.NNQLDPTSKEDFLNIC[160.03]IEPDTISK.G "sp|Q53H12|AGK_HUMAN,tr|E9PC15|E9PC15_HUMAN,tr|A0A3B3ITD0|A0A3B3ITD0_HUMAN,tr|A0A3B3ISY9|A0A3B3ISY9_HUMAN,tr|A0A0G2JLG5|A0A0G2JLG5_HUMAN,tr|A0A3B3ISZ0|A0A3B3ISZ0_HUMAN" 6 2790.3382 1.2 90590 23873 3 2790.332571 931.12 "Acylglycerol kinase, mitochondrial OS=Homo sapiens OX=9606 GN=AGK PE=1 SV=2" 4.11 3631.2 - 714542 - - - -2.0137 - 3.235 0.559 - 193.9 1 2 1 -0.0056 24 0 0 0 4.98E+07 4.14E+07 - - - 7.4975 1 221125_WJC_METTL3_EV_vs_WT_F06.23874.23874.3 6.65E-08 18/80 R.GRPGSGTSGVDSLSNFIESVK.E "sp|Q8IXT5|RB12B_HUMAN,tr|B9ZVT1|B9ZVT1_HUMAN,tr|E5RJ83|E5RJ83_HUMAN,tr|E5RHG1|E5RHG1_HUMAN,tr|E5RJV8|E5RJV8_HUMAN" 5 2093.0389 1.32 90591 23874 3 2093.043004 698.6869 RNA-binding protein 12B OS=Homo sapiens OX=9606 GN=RBM12B PE=1 SV=2 6.07 3631.4 - 439545 - - - 1.9551 - 3.849 0.598 - 352.4 1 2 0 0.0041 21 0 0 0 1.32E+07 1.00E+07 - - - 8.4373 0.7882 221125_WJC_METTL3_EV_vs_WT_F06.23878.23878.2 4.49 26-Jul K.SR[166.11]GLDSQQC[160.03]AQRQR.W sp|C9J442|CV046_HUMAN 1 1698.8208 - 90592 23878 2 1698.822457 850.4177 Uncharacterized protein C22orf46 OS=Homo sapiens OX=9606 GN=C22orf46 PE=5 SV=1 10.26 3631.9 - 1.57E+06 - - - 0.9942 - 1.209 0.097 - 105.4 1 2 2 0.0017 14 0 0 0 - - - - - 0.2332 1 221125_WJC_METTL3_EV_vs_WT_F06.23879.23879.3 7.34E-12 16/144 R.GAGFNQNNGAGSENFGLGVVPVSASPSSVEVHPVLEK[136.11].L "sp|Q7Z739|YTHD3_HUMAN,tr|A0A087X0Q1|A0A087X0Q1_HUMAN,tr|A0A024R7W5|A0A024R7W5_HUMAN,tr|A0A087WY31|A0A087WY31_HUMAN" 4 3658.8107 -1 90593 23879 3 3659.787076 1220.6108 YTH domain-containing family protein 3 OS=Homo sapiens OX=9606 GN=YTHDF3 PE=1 SV=1 4.75 3632.1 - 460088 - - - 266.855 - 3.229 0.687 - 130.3 1 2 0 0.9764 37 0 0 0 0.00E+00 0.00E+00 - - - 8.6257 0.9891 221125_WJC_METTL3_EV_vs_WT_F06.23884.23884.3 2.55E-08 18/144 R.GAGFNQNNGAGSENFGLGVVPVSASPSSVEVHPVLEK.L "sp|Q7Z739|YTHD3_HUMAN,tr|A0A087X0Q1|A0A087X0Q1_HUMAN,tr|A0A024R7W5|A0A024R7W5_HUMAN,tr|A0A087WY31|A0A087WY31_HUMAN" 4 3650.7965 -1 90597 23884 3 3651.776779 1217.9394 YTH domain-containing family protein 3 OS=Homo sapiens OX=9606 GN=YTHDF3 PE=1 SV=1 4.75 3632.7 - 863712 - - - 268.5099 - 3.295 0.667 - 116.5 1 2 0 0.9803 37 0 0 0 0.00E+00 0.00E+00 - - - 8.4481 0.9926 221125_WJC_METTL3_EV_vs_WT_F06.23888.23888.3 2.49E-07 Oct-84 K.TC[160.03]NC[160.03]ETEDYGEKFDENDVITC[160.03]F.A "sp|Q00839|HNRPU_HUMAN,tr|A0A1W2PQL0|A0A1W2PQL0_HUMAN,tr|A0A1W2PPL4|A0A1W2PPL4_HUMAN,tr|A0A1W2PQ74|A0A1W2PQ74_HUMAN,tr|Q5RI18|Q5RI18_HUMAN,tr|A0A1W2PP35|A0A1W2PP35_HUMAN,tr|A0A1W2PPS1|A0A1W2PPS1_HUMAN,tr|A0A1W2PRZ7|A0A1W2PRZ7_HUMAN,tr|A0A1W2PPH7|A0A1W2PPH7_HUMAN,tr|A0A1W2PP34|A0A1W2PP34_HUMAN,tr|A0A1X7SBS1|A0A1X7SBS1_HUMAN" 11 2745.0517 0.78 90600 23888 3 2745.053682 916.0245 Heterogeneous nuclear ribonucleoprotein U OS=Homo sapiens OX=9606 GN=HNRNPU PE=1 SV=6 3.66 3633.1 - 2.73E+06 - - - 0.7351 - 2.002 0.652 - 68.6 1 1 1 0.002 22 0 0 0 6.91E+07 8.88E+07 - - - 7.4543 1 221125_WJC_METTL3_EV_vs_WT_F06.23894.23894.2 1.70E-07 13/32 K.ELTTEIDNNIEQISSYK.S "sp|P13645|K1C10_HUMAN,tr|A0A1B0GVI3|A0A1B0GVI3_HUMAN" 2 1995.9637 999 90603 23894 2 1995.969614 998.9891 "Keratin, type I cytoskeletal 10 OS=Homo sapiens OX=9606 GN=KRT10 PE=1 SV=6" 4 3633.9 - 457320 - - - 2.9725 - 2.976 0.627 - 417.6 1 2 0 0.0059 17 0 0 0 1.86E+07 0.00E+00 - - - 6.3514 1 221125_WJC_METTL3_EV_vs_WT_F06.23899.23899.3 1.79E-07 18/64 K.ELTTEIDNNIEQISSYK.S "sp|P13645|K1C10_HUMAN,tr|A0A1B0GVI3|A0A1B0GVI3_HUMAN" 2 1995.9637 999 90606 23899 3 1995.967457 666.3285 "Keratin, type I cytoskeletal 10 OS=Homo sapiens OX=9606 GN=KRT10 PE=1 SV=6" 4 3634.6 - 693192 - - - 1.8918 - 2.91 0.524 - 351.7 1 2 0 0.0038 17 0 0 0 2.42E+07 0.00E+00 - - - 7.0795 1 221125_WJC_METTL3_EV_vs_WT_F06.23904.23904.4 5.09E-07 17/108 R.GLLQDDAHPTLVTYADHSK[136.11].L "sp|Q86U44|MTA70_HUMAN,tr|F5H6D8|F5H6D8_HUMAN,tr|H0YFV6|H0YFV6_HUMAN,tr|B4DTN4|B4DTN4_HUMAN" 4 2088.0367 0.01 90609 23904 4 2088.038508 523.0165 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 5.13 3635.2 - 900665 - - - 0.8501 - 3.119 0.527 - 273.4 1 2 0 0.0018 19 0 0 0 3.55E+05 3.63E+07 - - - 4.1973 0.9999 221125_WJC_METTL3_EV_vs_WT_F06.23905.23905.3 1.16E-08 15/64 K.AAIDWFDGK[136.11]EFSGNPIK[136.11].V "sp|P35637|FUS_HUMAN,tr|H3BPE7|H3BPE7_HUMAN" 2 1909.9545 0.94 90610 23905 3 1909.955678 637.6588 RNA-binding protein FUS OS=Homo sapiens OX=9606 GN=FUS PE=1 SV=1 4.56 3635.4 - 514527 - - - 0.6094 - 3.502 0.563 - 293.6 1 2 1 0.0012 17 0 0 0 1.68E+07 1.79E+07 - - - 7.9829 1 221125_WJC_METTL3_EV_vs_WT_F06.23908.23908.4 1.03E-05 22/96 R.R[166.11]HDYWLLAGIINHGYAR[166.11].W "sp|Q14839|CHD4_HUMAN,tr|A0A2R8Y4X2|A0A2R8Y4X2_HUMAN,tr|A0A2U3TZM0|A0A2U3TZM0_HUMAN,tr|A0A2R8YD40|A0A2R8YD40_HUMAN,tr|A0A2R8Y5J0|A0A2R8Y5J0_HUMAN,tr|A0A2R8Y425|A0A2R8Y425_HUMAN,tr|A0A2R8YFK9|A0A2R8YFK9_HUMAN,tr|A0A0C4DGG9|A0A0C4DGG9_HUMAN,tr|A0A2R8YFD8|A0A2R8YFD8_HUMAN,tr|A0A2R8YDW2|A0A2R8YDW2_HUMAN,tr|A0A2R8Y7I0|A0A2R8Y7I0_HUMAN,tr|F5GWX5|F5GWX5_HUMAN,tr|A0A2R8Y7M9|A0A2R8Y7M9_HUMAN,tr|A0A2R8Y521|A0A2R8Y521_HUMAN,tr|A0A2R8YDJ9|A0A2R8YDJ9_HUMAN,tr|A0A2R8Y212|A0A2R8Y212_HUMAN" 16 2074.0764 0.77 90613 23908 4 2074.079102 519.5264 Chromodomain-helicase-DNA-binding protein 4 OS=Homo sapiens OX=9606 GN=CHD4 PE=1 SV=2 8.6 3635.7 - 270317 - - - 1.3018 - 3.433 0.583 - 289.5 1 2 0 0.0027 17 0 0 0 2.94E+06 3.83E+06 - - - 4.7279 1 221125_WJC_METTL3_EV_vs_WT_F06.23912.23912.3 8.54E-08 14/72 R.GLLQDDAHPTLVTYADHSK[136.11].L "sp|Q86U44|MTA70_HUMAN,tr|F5H6D8|F5H6D8_HUMAN,tr|H0YFV6|H0YFV6_HUMAN,tr|B4DTN4|B4DTN4_HUMAN" 4 2088.0367 0.1 90615 23912 3 2088.039943 697.0195 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 5.13 3636.3 - 465707 - - - 1.5373 - 2.792 0.515 - 214.5 1 2 0 0.0032 19 0 0 0 3.17E+06 3.16E+07 - - - 6.8034 0.9623 221125_WJC_METTL3_EV_vs_WT_F06.23918.23918.4 0.306 6/114 K.ETYDWYPNHHTYAELMQTLR[166.11].F "sp|Q9Y291|RT33_HUMAN,tr|C9JBY7|C9JBY7_HUMAN" 2 2577.1622 0.99 90619 23918 4 2577.162585 645.2978 "28S ribosomal protein S33, mitochondrial OS=Homo sapiens OX=9606 GN=MRPS33 PE=1 SV=1" 5.28 3637.1 - 166649 - - - 0.1385 - 1.262 0.162 - 28.6 1 2 0 0.0004 20 0 0 0 2.71E+06 2.75E+06 - - - 0.7137 1 221125_WJC_METTL3_EV_vs_WT_F06.23921.23921.4 5.18E-11 30/162 R.ILNHVLQHAEPGNAQSVLEAIDTYC[160.03]EQK.E "sp|P21964|COMT_HUMAN,tr|E7EUU8|E7EUU8_HUMAN,tr|E7EMS6|E7EMS6_HUMAN,tr|F8WBW9|F8WBW9_HUMAN,tr|H7BZ45|H7BZ45_HUMAN,tr|A0A7I2V3G7|A0A7I2V3G7_HUMAN,tr|A0A7I2V370|A0A7I2V370_HUMAN" 7 3176.5561 0.79 90621 23921 4 3176.559275 795.1463 Catechol O-methyltransferase OS=Homo sapiens OX=9606 GN=COMT PE=1 SV=2 4.8 3637.4 - 1.24E+06 - - - 1.0112 - 4.867 0.587 - 584.7 1 2 0 0.0032 28 0 0 0 2.02E+07 2.57E+07 - - - 4.8257 1 221125_WJC_METTL3_EV_vs_WT_F06.23923.23923.4 6.97E-08 25/138 R.AEVQHQLHVAVGSLQESILAQVQR[166.11].L "sp|Q6P2E9|EDC4_HUMAN,tr|I3L3M2|I3L3M2_HUMAN" 2 2649.4226 0.92 90623 23923 4 2649.425921 663.3629 Enhancer of mRNA-decapping protein 4 OS=Homo sapiens OX=9606 GN=EDC4 PE=1 SV=1 6.01 3637.7 - 397992 - - - 1.2471 - 4.769 0.502 - 449.8 1 2 0 0.0033 24 0 0 0 9.53E+06 1.03E+07 - - - 4.0959 1 221125_WJC_METTL3_EV_vs_WT_F06.23930.23930.4 1.28E-13 31/210 R.ALIHAPPQR[166.11]PQDDYSVLFEDTSYADGYSPPLNVAQR[166.11].Y "sp|Q96ES7|SGF29_HUMAN,tr|H3BN84|H3BN84_HUMAN" 2 4049.9662 1.69 90626 23930 4 4049.965408 1013.4988 SAGA-associated factor 29 OS=Homo sapiens OX=9606 GN=SGF29 PE=1 SV=1 4.35 3638.5 - 2.12E+06 - - - -0.2079 - 4.027 0.675 - 379.6 1 2 0 -0.0008 36 0 0 0 4.91E+07 2.91E+07 - - - 5.5116 1 221125_WJC_METTL3_EV_vs_WT_F06.23932.23932.4 1.43E-19 33/198 R.AGELDQALGRPFTLSISNQYGDDEVTHTLQTESR.E sp|Q9BST9|RTKN_HUMAN 1 3747.7976 1.09 90628 23932 4 3747.806214 937.9567 Rhotekin OS=Homo sapiens OX=9606 GN=RTKN PE=1 SV=2 4.29 3638.7 - 1.25E+06 - - - 2.2915 - 6.732 0.743 - 737.4 1 2 0 0.0086 34 0 0 0 9.26E+06 8.48E+06 - - - 6.2593 1 221125_WJC_METTL3_EV_vs_WT_F06.23933.23933.2 1.71E-06 15/34 K.SSSPAPADIAQTVQEDLR[166.11].T "sp|Q13283|G3BP1_HUMAN,tr|A0A7I2V5M7|A0A7I2V5M7_HUMAN,tr|A0A7P0P2U7|A0A7P0P2U7_HUMAN,tr|A0A7I2YQU8|A0A7I2YQU8_HUMAN,tr|A0A7I2V651|A0A7I2V651_HUMAN,tr|A0A7I2V326|A0A7I2V326_HUMAN,tr|A0A7I2YQN9|A0A7I2YQN9_HUMAN" 7 1893.9308 1.83 90629 23933 2 1893.928502 947.9727 Ras GTPase-activating protein-binding protein 1 OS=Homo sapiens OX=9606 GN=G3BP1 PE=1 SV=1 4.03 3638.9 - 339493 - - - -1.1896 - 3.264 0.572 - 733.8 1 2 0 -0.0023 18 0 0 0 1.10E+07 6.02E+06 - - - 6.1734 1 221125_WJC_METTL3_EV_vs_WT_F06.23936.23936.4 3.51E-07 24/138 K.NELHNLLDKPQLQGIPVLVLGNKR.D "sp|Q96BM9|ARL8A_HUMAN,sp|Q9NVJ2|ARL8B_HUMAN" 2 2707.5497 1.27 90630 23936 4 2707.554017 677.8947 ADP-ribosylation factor-like protein 8A OS=Homo sapiens OX=9606 GN=ARL8A PE=1 SV=1 8.6 3639.3 - 1.30E+06 - - - 1.5874 - 3.699 0.609 - 493.3 1 2 0 0.0043 24 0 0 0 4.85E+07 3.81E+07 - - - 4.9454 1 221125_WJC_METTL3_EV_vs_WT_F06.23939.23939.4 5.07E-16 16/156 R.K[136.11]LDDDSDSPSFFEEK[136.11]PEEPVVLALDPK[136.11].G "sp|Q9H2P0|ADNP_HUMAN,tr|A0A2R8Y6X0|A0A2R8Y6X0_HUMAN,tr|A0A669KBJ7|A0A669KBJ7_HUMAN" 3 3069.5132 0.71 90632 23939 4 3069.52661 768.3856 Activity-dependent neuroprotector homeobox protein OS=Homo sapiens OX=9606 GN=ADNP PE=1 SV=1 3.97 3639.6 - 934766 - - - 4.3544 - 3.037 0.739 - 78.3 1 2 0 0.0134 27 0 0 0 2.01E+07 2.81E+07 - - - 6.0021 0.9999 221125_WJC_METTL3_EV_vs_WT_F06.23943.23943.3 2.00E-05 14/68 K.SSSPAPADIAQTVQEDLR.T "sp|Q13283|G3BP1_HUMAN,tr|A0A7I2V5M7|A0A7I2V5M7_HUMAN,tr|A0A7P0P2U7|A0A7P0P2U7_HUMAN,tr|A0A7I2YQU8|A0A7I2YQU8_HUMAN,tr|A0A7I2V651|A0A7I2V651_HUMAN,tr|A0A7I2V326|A0A7I2V326_HUMAN,tr|A0A7I2YQN9|A0A7I2YQN9_HUMAN" 7 1883.9225 0.41 90634 23943 3 1883.918694 628.9814 Ras GTPase-activating protein-binding protein 1 OS=Homo sapiens OX=9606 GN=G3BP1 PE=1 SV=1 4.03 3640.1 - 627687 - - - -2.0123 - 2.375 0.49 - 165.8 1 2 0 -0.0038 18 0 0 0 1.14E+07 2.78E+07 - - - 6.1559 0.9978 221125_WJC_METTL3_EV_vs_WT_F06.23944.23944.2 6.79E-08 13/28 K.QISNLQQSISDAEQR.G sp|P04264|K2C1_HUMAN 1 1715.8438 999 90635 23944 2 1715.852677 858.9292 "Keratin, type II cytoskeletal 1 OS=Homo sapiens OX=9606 GN=KRT1 PE=1 SV=6" 4.37 3640.3 - 293142 - - - 5.1497 - 2.399 0.543 - 526.4 1 2 0 0.0088 15 0 0 0 1.21E+07 0.00E+00 - - - 5.2002 0.9999 221125_WJC_METTL3_EV_vs_WT_F06.23945.23945.3 1.49E-08 17/80 K.VQALEEANNDLENKIQDWYDK.K sp|P35527|K1C9_HUMAN 1 2534.1925 48.19 90636 23945 3 2534.194377 845.7381 "Keratin, type I cytoskeletal 9 OS=Homo sapiens OX=9606 GN=KRT9 PE=1 SV=3" 4.02 3640.4 - 1.23E+06 - - - 0.7359 - 3.422 0.538 - 292.7 1 2 1 0.0019 21 0 0 0 1.69E+07 3.50E+05 - - - 7.4871 0.9997 221125_WJC_METTL3_EV_vs_WT_F06.23946.23946.4 5.80E-08 16/138 K.VAELYSIHNSGDKSDIQDLLESVR.L "sp|Q69YQ0|CYTSA_HUMAN,tr|C9J8U1|C9J8U1_HUMAN,tr|A0A494C1J1|A0A494C1J1_HUMAN,tr|F8WAN1|F8WAN1_HUMAN" 4 2687.3402 0.3 90637 23946 4 2687.347895 672.8423 Cytospin-A OS=Homo sapiens OX=9606 GN=SPECC1L PE=1 SV=2 4.43 3640.5 - 571473 - - - 2.8489 - 3.665 0.509 - 173.5 1 2 1 0.0077 24 0 0 0 4.19E+06 1.38E+07 - - - 4.0711 1 221125_WJC_METTL3_EV_vs_WT_F06.23947.23947.3 2.32E-09 19/116 Q.YTEEPLSQEPSVDAGVDC[160.03]SSIGGVPFFQHK.K "sp|P52732|KIF11_HUMAN,tr|A0A7I2V3A9|A0A7I2V3A9_HUMAN" 2 3279.503 54.44 90638 23947 3 3279.511893 1094.175 Kinesin-like protein KIF11 OS=Homo sapiens OX=9606 GN=KIF11 PE=1 SV=2 4.17 3640.6 - 519119 - - - 2.7044 - 3.613 0.687 - 150.8 1 1 0 0.0089 30 0 0 0 9.30E+06 1.71E+05 - - - 9.1522 1 221125_WJC_METTL3_EV_vs_WT_F06.23954.23954.4 2.60E-06 25/138 K.NELHNLLDK[136.11]PQLQGIPVLVLGNK[136.11]R[166.11].D "sp|Q96BM9|ARL8A_HUMAN,sp|Q9NVJ2|ARL8B_HUMAN" 2 2733.5864 1.27 90643 23954 4 2733.592272 684.4039 ADP-ribosylation factor-like protein 8A OS=Homo sapiens OX=9606 GN=ARL8A PE=1 SV=1 8.6 3641.5 - 2.02E+06 - - - 2.1521 - 4.059 0.641 - 413.2 1 2 0 0.0059 24 0 0 0 4.85E+07 3.81E+07 - - - 5.2533 1 221125_WJC_METTL3_EV_vs_WT_F06.23956.23956.4 5.54E-17 23/156 R.KLDDDSDSPSFFEEKPEEPVVLALDPK.G "sp|Q9H2P0|ADNP_HUMAN,tr|A0A2R8Y6X0|A0A2R8Y6X0_HUMAN,tr|A0A669KBJ7|A0A669KBJ7_HUMAN" 3 3045.4706 0.73 90645 23956 4 3045.482194 762.3749 Activity-dependent neuroprotector homeobox protein OS=Homo sapiens OX=9606 GN=ADNP PE=1 SV=1 3.97 3641.8 - 1.39E+06 - - - 3.7925 - 4.269 0.744 - 187.4 1 2 0 0.0115 27 0 0 0 2.07E+07 2.85E+07 - - - 6.1527 1 221125_WJC_METTL3_EV_vs_WT_F06.23957.23957.4 8.93E-09 23/192 K.STEEQLEEQQQQEEEVEEVEVEQVQVEADAQEK.A sp|Q8N5Z5|KCD17_HUMAN 1 3901.7349 6.1 90646 23957 4 3901.730564 976.441 BTB\POZ domain-containing protein KCTD17 OS=Homo sapiens OX=9606 GN=KCTD17 PE=1 SV=3 3.5 3641.9 - 1.28E+06 - - - -1.1036 - 4.359 0.595 - 320.5 1 2 0 -0.0043 33 0 0 0 1.05E+07 1.72E+06 - - - 4.8454 0.9999 221125_WJC_METTL3_EV_vs_WT_F06.23959.23959.4 6.64E-07 22/204 K.EGIC[160.03]ALGGTSELSSEGTQHSYSEEEK[136.11]YAFVNWINK[136.11].A "sp|P13797|PLST_HUMAN,tr|A0A0A0MSQ0|A0A0A0MSQ0_HUMAN" 2 3935.8131 0.44 90648 23959 4 3935.813903 984.9605 Plastin-3 OS=Homo sapiens OX=9606 GN=PLS3 PE=1 SV=4 4.47 3642.2 - 1.13E+06 - - - 0.2096 - 4.182 0.555 - 198.6 1 2 1 0.0008 35 0 0 0 5.67E+06 1.29E+07 - - - 4.4807 1 221125_WJC_METTL3_EV_vs_WT_F06.23961.23961.4 1.06E-12 29/138 R.AEVQHQLHVAVGSLQESILAQVQR.L "sp|Q6P2E9|EDC4_HUMAN,tr|I3L3M2|I3L3M2_HUMAN" 2 2639.4143 0.92 90650 23961 4 2639.418471 660.8609 Enhancer of mRNA-decapping protein 4 OS=Homo sapiens OX=9606 GN=EDC4 PE=1 SV=1 6.01 3642.5 - 789723 - - - 1.5625 - 4.661 0.55 - 572.2 1 2 0 0.0041 24 0 0 0 9.53E+06 1.03E+07 - - - 4.5061 0.8437 221125_WJC_METTL3_EV_vs_WT_F06.23966.23966.4 0.000822 10/156 R.RDNYVPEVSALDQEIIEVDPDTK[136.11]EMLK[136.11].L "sp|P08708|RS17_HUMAN,tr|H3BNC9|H3BNC9_HUMAN,tr|H0YN88|H0YN88_HUMAN,tr|A0A075B716|A0A075B716_HUMAN" 4 3161.5773 - 90653 23966 4 3161.55148 791.4016 40S ribosomal protein S17 OS=Homo sapiens OX=9606 GN=RPS17 PE=1 SV=2 4.07 3643.1 - 2.27E+06 - - - -8.1703 - 2.332 0.331 - 32.6 1 2 1 -0.0258 27 0 0 0 - - - - - 2.3648 1 221125_WJC_METTL3_EV_vs_WT_F06.23967.23967.3 2.28E-06 26/68 R.C[160.03]QHAAHIISELILTAQER.D sp|Q96I24|FUBP3_HUMAN 1 2089.0739 1.79 90654 23967 3 2089.079527 697.3652 Far upstream element-binding protein 3 OS=Homo sapiens OX=9606 GN=FUBP3 PE=1 SV=2 6 3643.1 - 1.84E+06 - - - 2.7136 - 4.676 0.607 - 1195.7 1 2 0 0.0057 18 0 0 0 4.51E+08 2.52E+08 - - - 9.1467 0.9999 221125_WJC_METTL3_EV_vs_WT_F06.23969.23969.4 8.06E-06 23/102 R.C[160.03]QHAAHIISELILTAQER[166.11].D sp|Q96I24|FUBP3_HUMAN 1 2099.0821 1.84 90656 23969 4 2099.08531 525.7778 Far upstream element-binding protein 3 OS=Homo sapiens OX=9606 GN=FUBP3 PE=1 SV=2 6 3643.4 - 1.16E+06 - - - 1.5159 - 3.818 0.442 - 535.6 1 2 0 0.0032 18 0 0 0 3.34E+08 1.81E+08 - - - 3.5312 1 221125_WJC_METTL3_EV_vs_WT_F06.23971.23971.3 4.32E-11 18/72 K.REEEEFNTGPLSVLTQSVK.N "sp|P62316|SMD2_HUMAN,tr|K7ERG4|K7ERG4_HUMAN" 2 2162.0855 1.65 90658 23971 3 2162.093228 721.7025 Small nuclear ribonucleoprotein Sm D2 OS=Homo sapiens OX=9606 GN=SNRPD2 PE=1 SV=1 4.49 3643.6 - 717120 - - - 3.5614 - 3.607 0.653 - 538.5 1 2 0 0.0077 19 0 0 0 4.09E+07 2.48E+07 - - - 8.9699 0.9998 221125_WJC_METTL3_EV_vs_WT_F06.23976.23976.4 0.00427 22/102 R.C[160.03]QHAAHIISELILTAQER.D sp|Q96I24|FUBP3_HUMAN 1 2089.0739 1.82 90661 23976 4 2089.081869 523.2757 Far upstream element-binding protein 3 OS=Homo sapiens OX=9606 GN=FUBP3 PE=1 SV=2 6 3644.3 - 2.02E+06 - - - 3.8347 - 3.793 0.473 - 468.7 1 2 0 0.008 18 0 0 0 3.29E+08 1.80E+08 - - - 3.7975 1 221125_WJC_METTL3_EV_vs_WT_F06.23978.23978.3 8.98E-07 18/88 K.NSQEDVFYEDDIWPGENENGAEK.V "sp|Q8IZH2|XRN1_HUMAN,tr|H7C5E4|H7C5E4_HUMAN" 2 2684.115 2.1 90663 23978 3 2684.120358 895.7123 5'-3' exoribonuclease 1 OS=Homo sapiens OX=9606 GN=XRN1 PE=1 SV=1 3.62 3644.6 - 942511 - - - 1.9776 - 3.646 0.599 - 237.6 1 2 0 0.0053 23 0 0 0 1.97E+07 9.36E+06 - - - 8.2516 1 221125_WJC_METTL3_EV_vs_WT_F06.23981.23981.3 5.86E-15 24/128 R.AQAETGPTSFPSPVSVSMKPDLPVSLPTQTAPK.Q sp|Q96T58|MINT_HUMAN 1 3364.7225 1.86 90666 23981 3 3364.724099 1122.5814 Msx2-interacting protein OS=Homo sapiens OX=9606 GN=SPEN PE=1 SV=1 6.11 3645 - 711527 - - - 0.4874 - 4.472 0.707 - 363.7 1 2 0 0.0016 33 0 0 0 9.87E+06 5.31E+06 - - - 9.8679 0.9999 221125_WJC_METTL3_EV_vs_WT_F06.23984.23984.3 8.67E-12 18/72 K.R[166.11]EEEEFNTGPLSVLTQSVK[136.11].N "sp|P62316|SMD2_HUMAN,tr|K7ERG4|K7ERG4_HUMAN" 2 2180.108 1.65 90669 23984 3 2180.116516 727.7099 Small nuclear ribonucleoprotein Sm D2 OS=Homo sapiens OX=9606 GN=SNRPD2 PE=1 SV=1 4.49 3645.4 - 501618 - - - 3.9071 - 3.438 0.617 - 431.1 1 2 0 0.0085 19 0 0 0 4.08E+07 2.48E+07 - - - 8.4505 0.9987 221125_WJC_METTL3_EV_vs_WT_F06.23985.23985.3 3.18E-05 14/64 K.SQQLSSELDKLSQELEK.V sp|Q9P219|DAPLE_HUMAN 1 1960.9953 2.22 90670 23985 3 1961.003108 654.6724 Protein Daple OS=Homo sapiens OX=9606 GN=CCDC88C PE=1 SV=3 4.41 3645.5 - 452379 - - - 3.9735 - 2.833 0.457 - 152.4 1 2 1 0.0078 17 0 0 0 3.95E+06 1.77E+06 - - - 6.2637 1 221125_WJC_METTL3_EV_vs_WT_F06.23989.23989.4 3.44E-18 33/210 R.ALIHAPPQRPQDDYSVLFEDTSYADGYSPPLNVAQR.Y "sp|Q96ES7|SGF29_HUMAN,tr|H3BN84|H3BN84_HUMAN" 2 4029.9497 -1 90672 23989 4 4029.958452 1008.4947 SAGA-associated factor 29 OS=Homo sapiens OX=9606 GN=SGF29 PE=1 SV=1 4.35 3646 - 1.18E+06 - - - 2.1693 - 4.461 0.734 - 494.9 1 2 0 0.0087 36 0 0 0 0.00E+00 0.00E+00 - - - 6.0531 1 221125_WJC_METTL3_EV_vs_WT_F06.23991.23991.4 9.74E-07 25/132 K.GRPEQLGSPLHSSYLNSFFQLQR.G sp|Q8N2G6|ZCH24_HUMAN 1 2660.3459 1.3 90674 23991 4 2660.34528 666.0938 Zinc finger CCHC domain-containing protein 24 OS=Homo sapiens OX=9606 GN=ZCCHC24 PE=1 SV=1 8.75 3646.3 - 1.12E+06 - - - -0.2455 - 3.815 0.546 - 415.9 1 2 0 -0.0007 23 0 0 0 4.54E+07 3.50E+07 - - - 4.412 1 221125_WJC_METTL3_EV_vs_WT_F06.23992.23992.4 2.33E-08 24/132 K.GR[166.11]PEQLGSPLHSSYLNSFFQLQR[166.11].G sp|Q8N2G6|ZCH24_HUMAN 1 2680.3625 1.25 90675 23992 4 2680.364856 671.0979 Zinc finger CCHC domain-containing protein 24 OS=Homo sapiens OX=9606 GN=ZCCHC24 PE=1 SV=1 8.75 3646.4 - 798219 - - - 0.8891 - 4.029 0.544 - 333.3 1 2 0 0.0024 23 0 0 0 4.54E+07 3.63E+07 - - - 4.4118 1 221125_WJC_METTL3_EV_vs_WT_F06.23993.23993.4 2.95E-06 13/162 R.DSLPFDFQGHSGPPFANVEEHSFSYGAR.D sp|P78332|RBM6_HUMAN 1 3094.3846 2.37 90676 23993 4 3094.386875 774.6034 RNA-binding protein 6 OS=Homo sapiens OX=9606 GN=RBM6 PE=1 SV=5 4.72 3646.5 - 267704 - - - 0.7472 - 2.948 0.515 - 82.2 1 2 0 0.0023 28 0 0 0 1.91E+07 8.08E+06 - - - 4.0436 1 221125_WJC_METTL3_EV_vs_WT_F06.23996.23996.3 2.91E-19 31/116 R.QTAEESGITNSASSTLLSEYNVTNNSVALR.T sp|Q99459|CDC5L_HUMAN 1 3155.5218 1.41 90677 23996 3 3155.523418 1052.8479 Cell division cycle 5-like protein OS=Homo sapiens OX=9606 GN=CDC5L PE=1 SV=2 4.25 3646.9 - 1.32E+06 - - - 0.4985 - 4.743 0.768 - 844.2 1 2 0 0.0016 30 0 0 0 3.09E+07 2.18E+07 - - - 10.6833 1 221125_WJC_METTL3_EV_vs_WT_F06.23997.23997.3 6.21E-13 22/72 K.HSVDGESLSSELQQLGLPK.E "sp|Q9H0A8|COMD4_HUMAN,tr|H3BM91|H3BM91_HUMAN,tr|H3BPG2|H3BPG2_HUMAN,tr|A0A0B4J287|A0A0B4J287_HUMAN,tr|H3BQF2|H3BQF2_HUMAN" 5 2023.0222 1.25 90678 23997 3 2023.025783 675.348 COMM domain-containing protein 4 OS=Homo sapiens OX=9606 GN=COMMD4 PE=1 SV=1 4.65 3647.1 - 604636 - - - 1.7716 - 4.101 0.694 - 493.4 1 2 0 0.0036 19 0 0 0 7.38E+06 5.89E+06 - - - 9.7435 0.9995 221125_WJC_METTL3_EV_vs_WT_F06.24007.24007.3 3.23E-06 13/88 K.NSQEDVFYEDDIWPGENENGAEK[136.11].V "sp|Q8IZH2|XRN1_HUMAN,tr|H7C5E4|H7C5E4_HUMAN" 2 2692.1292 2.1 90686 24007 3 2693.132248 898.3837 5'-3' exoribonuclease 1 OS=Homo sapiens OX=9606 GN=XRN1 PE=1 SV=1 3.62 3648.4 - 739213 - - - 372.5668 - 2.699 0.58 - 113.4 1 2 0 1.003 23 0 0 0 1.97E+07 9.36E+06 - - - 7.0578 1 221125_WJC_METTL3_EV_vs_WT_F06.24026.24026.4 8.91E-14 32/168 K.TAVIDHHNYDISDLGQHTLIVADTENLLK.A "sp|P39656|OST48_HUMAN,tr|U3KQ84|U3KQ84_HUMAN,tr|A0A0C4DGS1|A0A0C4DGS1_HUMAN" 3 3244.6364 1.24 90694 24026 4 3244.64359 812.1664 Dolichyl-diphosphooligosaccharide--protein glycosyltransferase 48 kDa subunit OS=Homo sapiens OX=9606 GN=DDOST PE=1 SV=4 4.7 3650.9 - 1.76E+06 - - - 2.2095 - 4.691 0.671 - 618.8 1 2 0 0.0072 29 0 0 0 6.26E+07 5.05E+07 - - - 5.5407 1 221125_WJC_METTL3_EV_vs_WT_F06.24029.24029.3 0.00123 26/68 R.C[160.03]QHAAHIISELILTAQER[166.11].D sp|Q96I24|FUBP3_HUMAN 1 2099.0821 1.79 90695 24029 3 2099.084314 700.7013 Far upstream element-binding protein 3 OS=Homo sapiens OX=9606 GN=FUBP3 PE=1 SV=2 6 3651.3 - 4.85E+06 - - - 1.0414 - 4.677 0.59 - 1243.7 1 2 0 0.0022 18 0 0 0 4.51E+08 2.51E+08 - - - 8.9587 1 221125_WJC_METTL3_EV_vs_WT_F06.24033.24033.4 2.88E-12 24/132 K.KLSELSNSQQSVQTLSLWLIHHR.K "sp|Q96P16|RPR1A_HUMAN,sp|Q9NQG5|RPR1B_HUMAN,tr|E9PIQ9|E9PIQ9_HUMAN,tr|E9PQF3|E9PQF3_HUMAN,tr|A0A0C4DGQ6|A0A0C4DGQ6_HUMAN,tr|K7EQR8|K7EQR8_HUMAN" 6 2703.4456 1.56 90699 24033 4 2703.449963 676.8687 Regulation of nuclear pre-mRNA domain-containing protein 1A OS=Homo sapiens OX=9606 GN=RPRD1A PE=1 SV=1 8.76 3651.8 - 580607 - - - 1.5965 - 4.272 0.629 - 511.4 1 2 0 0.0043 23 0 0 0 1.30E+07 8.36E+06 - - - 5.1701 1 221125_WJC_METTL3_EV_vs_WT_F06.24034.24034.3 2.74E-12 21/116 R.QTAEESGITNSASSTLLSEYNVTNNSVALR[166.11].T sp|Q99459|CDC5L_HUMAN 1 3165.5301 1.41 90700 24034 3 3165.539041 1056.184 Cell division cycle 5-like protein OS=Homo sapiens OX=9606 GN=CDC5L PE=1 SV=2 4.25 3651.9 - 470190 - - - 2.8197 - 3.553 0.65 - 374.7 1 2 0 0.0089 30 0 0 0 3.09E+07 2.18E+07 - - - 8.7011 0.9998 221125_WJC_METTL3_EV_vs_WT_F06.24038.24038.4 3.21E-05 16/108 R.ETLRPLAYSTLADLVHHVR.Q "sp|Q9Y4A5|TRRAP_HUMAN,tr|H0Y4W2|H0Y4W2_HUMAN,tr|F2Z2U4|F2Z2U4_HUMAN" 3 2190.1909 1.01 90702 24038 4 2190.192834 548.555 Transformation\transcription domain-associated protein OS=Homo sapiens OX=9606 GN=TRRAP PE=1 SV=3 7.02 3652.4 - 435902 - - - 0.8666 - 2.798 0.383 - 228.2 1 2 0 0.0019 19 0 0 0 6.73E+06 6.67E+06 - - - 2.9072 0.9996 221125_WJC_METTL3_EV_vs_WT_F06.24039.24039.4 2.94E-06 18/108 R.ETLR[166.11]PLAYSTLADLVHHVR[166.11].Q "sp|Q9Y4A5|TRRAP_HUMAN,tr|H0Y4W2|H0Y4W2_HUMAN,tr|F2Z2U4|F2Z2U4_HUMAN" 3 2210.2075 1 90703 24039 4 2210.209847 553.5591 Transformation\transcription domain-associated protein OS=Homo sapiens OX=9606 GN=TRRAP PE=1 SV=3 7.02 3652.6 - 339937 - - - 1.0727 - 3.397 0.325 - 388.6 1 2 0 0.0024 19 0 0 0 6.68E+06 6.67E+06 - - - 2.4678 1 221125_WJC_METTL3_EV_vs_WT_F06.24050.24050.4 2.48E-17 32/168 K.TAVIDHHNYDISDLGQHTLIVADTENLLK[136.11].A "sp|P39656|OST48_HUMAN,tr|U3KQ84|U3KQ84_HUMAN,tr|A0A0C4DGS1|A0A0C4DGS1_HUMAN" 3 3252.6506 1.24 90709 24050 4 3252.652066 814.1699 Dolichyl-diphosphooligosaccharide--protein glycosyltransferase 48 kDa subunit OS=Homo sapiens OX=9606 GN=DDOST PE=1 SV=4 4.7 3654 - 2.69E+06 - - - 0.4443 - 5.387 0.72 - 725.7 1 2 0 0.0014 29 0 0 0 6.26E+07 5.05E+07 - - - 6.0115 0.9894 221125_WJC_METTL3_EV_vs_WT_F06.24056.24056.3 6.68E-08 18/104 R.RDNYVPEVSALDQEIIEVDPDTK[136.11]EMLK[136.11].L "sp|P08708|RS17_HUMAN,tr|H3BNC9|H3BNC9_HUMAN,tr|H0YN88|H0YN88_HUMAN,tr|A0A075B716|A0A075B716_HUMAN" 4 3161.5773 - 90712 24056 3 3161.549846 1054.8664 40S ribosomal protein S17 OS=Homo sapiens OX=9606 GN=RPS17 PE=1 SV=2 4.07 3654.7 - 644082 - - - -8.6871 - 3.264 0.538 - 175.1 1 2 1 -0.0275 27 0 0 0 - - - - - 7.2521 1 221125_WJC_METTL3_EV_vs_WT_F06.24063.24063.3 2.47E-10 23/64 K.DKNEQAFEEVFQNANFR.S "sp|P27694|RFA1_HUMAN,tr|I3L4R8|I3L4R8_HUMAN" 2 2084.9552 1.27 90717 24063 3 2084.958206 695.9923 Replication protein A 70 kDa DNA-binding subunit OS=Homo sapiens OX=9606 GN=RPA1 PE=1 SV=2 4.41 3655.6 - 1.10E+07 - - - 1.4504 - 3.837 0.587 - 795.3 1 2 1 0.003 17 0 0 0 2.39E+08 1.88E+08 - - - 8.4807 0.999 221125_WJC_METTL3_EV_vs_WT_F06.24069.24069.4 2.31E-07 21/156 R.GFGFVTFADPASVDK[136.11]VLGQPHHELDSK[136.11].T "sp|Q96DH6|MSI2H_HUMAN,tr|B4DHE8|B4DHE8_HUMAN,tr|A0A6Q8PF05|A0A6Q8PF05_HUMAN,tr|J3QKT5|J3QKT5_HUMAN,tr|A0A6Q8PFU8|A0A6Q8PFU8_HUMAN,tr|J3KTC1|J3KTC1_HUMAN,tr|A0A6Q8PHT3|A0A6Q8PHT3_HUMAN" 7 2913.4632 2.07 90721 24069 4 2913.476331 729.3731 RNA-binding protein Musashi homolog 2 OS=Homo sapiens OX=9606 GN=MSI2 PE=1 SV=1 5.26 3656.4 - 688813 - - - 4.5043 - 3.704 0.518 - 245.9 1 2 1 0.0131 27 0 0 0 3.55E+07 1.72E+07 - - - 4.1407 1 221125_WJC_METTL3_EV_vs_WT_F06.24071.24071.4 4.94E-10 23/126 K.HPSVESVVQC[160.03]EIDEDVIQVSK[136.11]K[136.11].F "sp|P19623|SPEE_HUMAN,tr|K7ESL0|K7ESL0_HUMAN" 2 2540.2763 0.23 90722 24071 4 2540.280157 636.0764 Spermidine synthase OS=Homo sapiens OX=9606 GN=SRM PE=1 SV=1 4.5 3656.6 - 861011 - - - 1.5109 - 3.816 0.593 - 536.9 1 2 0 0.0038 22 0 0 0 5.93E+06 2.54E+07 - - - 4.8246 0.9999 221125_WJC_METTL3_EV_vs_WT_F06.24074.24074.4 9.38E-10 26/156 R.GFGFVTFADPASVDKVLGQPHHELDSK.T "sp|Q96DH6|MSI2H_HUMAN,tr|B4DHE8|B4DHE8_HUMAN,tr|A0A6Q8PF05|A0A6Q8PF05_HUMAN,tr|J3QKT5|J3QKT5_HUMAN,tr|A0A6Q8PFU8|A0A6Q8PFU8_HUMAN,tr|J3KTC1|J3KTC1_HUMAN,tr|A0A6Q8PHT3|A0A6Q8PHT3_HUMAN" 7 2897.4348 2.07 90724 24074 4 2897.43847 725.366 RNA-binding protein Musashi homolog 2 OS=Homo sapiens OX=9606 GN=MSI2 PE=1 SV=1 5.26 3656.9 - 1.43E+06 - - - 1.2639 - 4.535 0.538 - 393.3 1 2 1 0.0037 27 0 0 0 3.62E+07 1.75E+07 - - - 4.3808 1 221125_WJC_METTL3_EV_vs_WT_F06.24084.24084.2 0.000859 26-Dec K.LISWYDNEFGYSNR[166.11].V "sp|P04406|G3P_HUMAN,tr|E7EUT5|E7EUT5_HUMAN" 2 1772.8034 1.24 90730 24084 2 1772.808501 887.409 Glyceraldehyde-3-phosphate dehydrogenase OS=Homo sapiens OX=9606 GN=GAPDH PE=1 SV=3 4.37 3658.2 - 809524 - - - 2.8943 - 2.638 0.596 - 480.7 1 2 0 0.0051 14 0 0 0 3.73E+07 3.00E+07 - - - 5.8757 0.9977 221125_WJC_METTL3_EV_vs_WT_F06.24085.24085.4 0.000346 9/120 K.AHVLAASVEQATENFLEK[136.11]GDK[136.11].L "sp|P35221|CTNA1_HUMAN,tr|E5RHV7|E5RHV7_HUMAN,tr|E5RJL0|E5RJL0_HUMAN,tr|E5RIE0|E5RIE0_HUMAN,tr|E5RIB1|E5RIB1_HUMAN,tr|E5RGY6|E5RGY6_HUMAN,tr|E5RG03|E5RG03_HUMAN,tr|E5RFM3|E5RFM3_HUMAN,tr|G3XAM7|G3XAM7_HUMAN" 9 2272.167 1.95 90731 24085 4 2272.17284 569.049 Catenin alpha-1 OS=Homo sapiens OX=9606 GN=CTNNA1 PE=1 SV=1 4.83 3658.3 - 113409 - - - 2.5588 - 2.009 0.371 - 48 1 2 1 0.0058 21 0 0 0 7.83E+06 4.02E+06 - - - 2.6842 0.9983 221125_WJC_METTL3_EV_vs_WT_F06.24086.24086.4 5.49E-05 19/132 K.AKDIVPGDIVEIAVGDKVPADIR.L sp|P16615|AT2A2_HUMAN 1 2389.3217 3.99 90732 24086 4 2389.329394 598.3377 Sarcoplasmic\endoplasmic reticulum calcium ATPase 2 OS=Homo sapiens OX=9606 GN=ATP2A2 PE=1 SV=1 4.36 3658.5 - 339877 - - - 3.2302 - 3.086 0.405 - 163.6 1 2 2 0.0077 23 0 0 0 5.84E+06 1.46E+06 - - - 3.1141 0.9985 221125_WJC_METTL3_EV_vs_WT_F06.24095.24095.3 0.00905 Sep-52 K.LISWYDNEFGYSNR.V "sp|P04406|G3P_HUMAN,tr|E7EUT5|E7EUT5_HUMAN" 2 1762.7951 1.17 90737 24095 3 1762.801501 588.6056 Glyceraldehyde-3-phosphate dehydrogenase OS=Homo sapiens OX=9606 GN=GAPDH PE=1 SV=3 4.37 3659.6 - 406273 - - - 3.6312 - 1.556 0.42 - 106 1 2 0 0.0064 14 0 0 0 8.55E+06 7.33E+06 - - - 4.3958 0.9999 221125_WJC_METTL3_EV_vs_WT_F06.24099.24099.3 0.000141 Dec-52 K.LISWYDNEFGYSNR[166.11].V "sp|P04406|G3P_HUMAN,tr|E7EUT5|E7EUT5_HUMAN" 2 1772.8034 1.17 90739 24099 3 1772.806671 591.9417 Glyceraldehyde-3-phosphate dehydrogenase OS=Homo sapiens OX=9606 GN=GAPDH PE=1 SV=3 4.37 3660.2 - 465397 - - - 1.862 - 2.406 0.435 - 183.6 1 2 0 0.0033 14 0 0 0 8.55E+06 7.33E+06 - - - 5.7221 0.9999 221125_WJC_METTL3_EV_vs_WT_F06.24100.24100.4 8.47E-05 12/156 K.DKPVQIRPWNLSDSDFVMDGSQPLDPR.K "sp|Q7Z5Q1|CPEB2_HUMAN,sp|Q8NE35|CPEB3_HUMAN,sp|Q17RY0|CPEB4_HUMAN,tr|A0A5K1VW71|A0A5K1VW71_HUMAN,tr|A0A590UJI5|A0A590UJI5_HUMAN,tr|A0A5K1VW93|A0A5K1VW93_HUMAN,tr|A0A5K1VW61|A0A5K1VW61_HUMAN,tr|H0Y9D9|H0Y9D9_HUMAN,tr|A0A5K1VW79|A0A5K1VW79_HUMAN,tr|E5RJM0|E5RJM0_HUMAN,tr|E5RFP2|E5RFP2_HUMAN,tr|B7ZLQ8|B7ZLQ8_HUMAN" 12 3111.5084 0.99 90740 24100 4 3111.512493 778.8844 Cytoplasmic polyadenylation element-binding protein 2 OS=Homo sapiens OX=9606 GN=CPEB2 PE=2 SV=3 4.28 3660.3 - 624033 - - - 1.3206 - 2.406 0.419 - 40.3 1 2 0 0.0041 27 0 0 0 5.44E+06 5.47E+06 - - - 3.1465 1 221125_WJC_METTL3_EV_vs_WT_F06.24105.24105.4 1.95E-15 31/156 R.GRGLEDGEAGEEEEKEPLPSLDVFLSR.Y "sp|Q96DF8|ESS2_HUMAN,tr|F8WEF8|F8WEF8_HUMAN" 2 2957.4254 0.54 90743 24105 4 2957.4405 740.3636 Splicing factor ESS-2 homolog OS=Homo sapiens OX=9606 GN=ESS2 PE=1 SV=1 4.1 3661 - 2.48E+06 - - - 5.0973 - 5.127 0.69 - 753.7 1 2 2 0.0151 27 0 0 0 2.61E+07 4.86E+07 - - - 5.739 0.9994 221125_WJC_METTL3_EV_vs_WT_F06.24112.24112.3 1.15E-08 14/76 R.SASSASSLFSPSSTLFSSSR.L "sp|Q14671|PUM1_HUMAN,tr|Q5T1Z8|Q5T1Z8_HUMAN,tr|H0YDK8|H0YDK8_HUMAN,tr|H0YEH2|H0YEH2_HUMAN,tr|Q5T1Z4|Q5T1Z4_HUMAN,tr|E9PR38|E9PR38_HUMAN" 6 1991.9436 0.8 90750 24112 3 1991.955109 664.9885 Pumilio homolog 1 OS=Homo sapiens OX=9606 GN=PUM1 PE=1 SV=3 9.47 3661.9 - 365045 - - - 5.7707 - 3.179 0.506 - 189.5 1 2 0 0.0115 20 0 0 0 3.94E+06 4.92E+06 - - - 6.9841 1 221125_WJC_METTL3_EV_vs_WT_F06.24124.24124.4 7.78E-13 27/150 K.THTC[160.03]PPC[160.03]PAPELLGGPSVFLFPPKPK.D "sp|P01857|IGHG1_HUMAN,tr|A0A0A0MS08|A0A0A0MS08_HUMAN,tr|A0A0A0MS07|A0A0A0MS07_HUMAN" 3 2843.4503 999 90758 24124 4 2843.460412 711.8698 Immunoglobulin heavy constant gamma 1 OS=Homo sapiens OX=9606 GN=IGHG1 PE=1 SV=1 7.76 3663.4 - 1.47E+06 - - - 3.5689 - 3.664 0.745 - 338.1 1 2 0 0.0101 26 0 0 0 2.81E+07 0.00E+00 - - - 6.1173 1 221125_WJC_METTL3_EV_vs_WT_F06.24126.24126.4 9.42E-12 20/156 R.GR[166.11]GLEDGEAGEEEEK[136.11]EPLPSLDVFLSR[166.11].Y "sp|Q96DF8|ESS2_HUMAN,tr|F8WEF8|F8WEF8_HUMAN" 2 2985.4562 0.72 90760 24126 4 2985.46381 747.3713 Splicing factor ESS-2 homolog OS=Homo sapiens OX=9606 GN=ESS2 PE=1 SV=1 4.1 3663.7 - 1.69E+06 - - - 2.5607 - 3.715 0.641 - 239.3 1 2 2 0.0076 27 0 0 0 2.65E+07 3.70E+07 - - - 5.2138 0.9997 221125_WJC_METTL3_EV_vs_WT_F06.24143.24143.3 7.38E-09 18/68 K.YVHYEIDAC[160.03]MDSEAPGSK[136.11].D "sp|Q86U44|MTA70_HUMAN,tr|H0YFV6|H0YFV6_HUMAN" 2 2078.8805 0 90773 24143 3 2079.884731 693.9674 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 4.31 3665.9 - 799979 - - - 483.0672 - 3.293 0.601 - 336.9 1 2 0 1.0042 18 0 0 0 7.04E+04 6.25E+07 - - - 7.9301 1 221125_WJC_METTL3_EV_vs_WT_F06.24146.24146.4 1.75E-08 15/120 K.FENAFLSHVVSQHQALLGTIR.A sp|P25705|ATPA_HUMAN 1 2366.2495 1.51 90776 24146 4 2366.2582 592.5697 "ATP synthase subunit alpha, mitochondrial OS=Homo sapiens OX=9606 GN=ATP5F1A PE=1 SV=1" 6.92 3666.3 - 477080 - - - 3.6708 - 3.054 0.632 - 145.1 1 2 0 0.0087 21 0 0 0 6.17E+06 4.08E+06 - - - 5.0937 0.8387 221125_WJC_METTL3_EV_vs_WT_F06.24151.24151.3 0.00082 10/104 K.TKKPGAGDTAFPGTGGFSATFDYQQAF.G sp|Q96PK6|RBM14_HUMAN 1 2766.2926 10.27 90779 24151 3 2766.289618 923.1048 RNA-binding protein 14 OS=Homo sapiens OX=9606 GN=RBM14 PE=1 SV=2 5.63 3666.9 - 632900 - - - -1.0635 - 2.236 0.326 - 81.7 1 1 1 -0.0029 27 0 0 0 1.02E+07 9.98E+05 - - - 4.0251 0.9999 221125_WJC_METTL3_EV_vs_WT_F06.24153.24153.3 1.28E-09 19/88 R.SALQSINEWAAQTTDGKLPEVTK.D "sp|P50454|SERPH_HUMAN,tr|E9PNX1|E9PNX1_HUMAN,tr|E9PPV6|E9PPV6_HUMAN,tr|E9PR70|E9PR70_HUMAN,tr|E9PMI5|E9PMI5_HUMAN,tr|E9PJH8|E9PJH8_HUMAN,tr|E9PK86|E9PK86_HUMAN" 7 2486.2653 1.42 90781 24153 3 2486.269984 829.7624 Serpin H1 OS=Homo sapiens OX=9606 GN=SERPINH1 PE=1 SV=2 4.68 3667.2 - 863542 - - - 1.8908 - 3.632 0.556 - 323.4 1 2 1 0.0047 23 0 0 0 2.83E+07 1.99E+07 - - - 7.7633 1 221125_WJC_METTL3_EV_vs_WT_F06.24154.24154.4 5.97E-07 21/180 R.FVSEAWQQVQQQLDGGPAGEGGPRPVQYVER.T sp|Q9BUT9|MCRI2_HUMAN 1 3411.6596 1.9 90782 24154 4 3411.662472 853.9222 MAPK regulated corepressor interacting protein 2 OS=Homo sapiens OX=9606 GN=MCRIP2 PE=1 SV=2 4.41 3667.3 - 746970 - - - 0.8371 - 3.495 0.467 - 175.2 1 2 0 0.0029 31 0 0 0 8.88E+06 4.67E+06 - - - 3.6703 1 221125_WJC_METTL3_EV_vs_WT_F06.24170.24170.3 2.56E-07 18/76 K.FEAHPNDLYVEGLPENIPFR.S "sp|P78347|GTF2I_HUMAN,tr|A0A494C0Q7|A0A494C0Q7_HUMAN,tr|A0A494C1K3|A0A494C1K3_HUMAN" 3 2356.1488 2.73 90793 24170 3 2356.1499 786.3902 General transcription factor II-I OS=Homo sapiens OX=9606 GN=GTF2I PE=1 SV=2 4.4 3669.4 - 670411 - - - 0.4681 - 2.904 0.578 - 207.9 1 2 0 0.0011 20 0 0 0 4.52E+07 1.66E+07 - - - 7.5702 0.9999 221125_WJC_METTL3_EV_vs_WT_F06.24176.24176.4 1.89E-10 21/144 R.EVVK[136.11]HPSVESVVQC[160.03]EIDEDVIQVSK[136.11].K "sp|P19623|SPEE_HUMAN,tr|K7ESL0|K7ESL0_HUMAN" 2 2867.4557 0.44 90797 24176 4 2867.463003 717.8712 Spermidine synthase OS=Homo sapiens OX=9606 GN=SRM PE=1 SV=1 4.35 3670.2 - 454082 - - - 2.5329 - 3.717 0.615 - 363.6 1 2 1 0.0073 25 0 0 0 5.85E+06 1.32E+07 - - - 4.9946 0.997 221125_WJC_METTL3_EV_vs_WT_F06.24181.24181.4 0.00357 14/138 K.QK[136.11]VPPVLQVLHC[160.03]GDESMLDIGGER[166.11].G sp|Q9UJV9|DDX41_HUMAN 1 2694.3588 0.9 90800 24181 4 2694.356317 674.597 Probable ATP-dependent RNA helicase DDX41 OS=Homo sapiens OX=9606 GN=DDX41 PE=1 SV=2 4.75 3670.9 - 646825 - - - -0.9316 - 2.5 0.305 - 112.2 1 2 1 -0.0025 24 0 0 0 1.58E+07 1.76E+07 - - - 2.1741 1 221125_WJC_METTL3_EV_vs_WT_F06.24186.24186.3 1.20E-10 17/60 K.K[136.11]VSQEILELLNTTTAK[136.11].E "sp|Q86U44|MTA70_HUMAN,tr|H0YFV6|H0YFV6_HUMAN" 2 1803.0324 0.01 90802 24186 3 1803.030306 602.0181 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 6.14 3671.6 - 8.41E+06 - - - -1.178 - 3.762 0.619 - 476.6 1 2 0 -0.0021 16 0 0 0 9.94E+07 1.47E+10 - - - 8.8403 1 221125_WJC_METTL3_EV_vs_WT_F06.24187.24187.4 1.23E-08 20/132 K.DNVSSPGGATIHALHVLESGGFR[166.11].S "sp|P32322|P5CR1_HUMAN,tr|J3QKT4|J3QKT4_HUMAN,tr|E2QRB3|E2QRB3_HUMAN,tr|J3KQ22|J3KQ22_HUMAN" 4 2330.1643 0.9 90803 24187 4 2330.163601 583.5483 "Pyrroline-5-carboxylate reductase 1, mitochondrial OS=Homo sapiens OX=9606 GN=PYCR1 PE=1 SV=2" 5.99 3671.7 - 801971 - - - -0.2901 - 3.51 0.592 - 241.3 1 2 0 -0.0007 23 0 0 0 6.96E+07 7.69E+07 - - - 4.7854 1 221125_WJC_METTL3_EV_vs_WT_F06.24188.24188.4 2.42E-09 24/132 K.DNVSSPGGATIHALHVLESGGFR.S "sp|P32322|P5CR1_HUMAN,tr|J3QKT4|J3QKT4_HUMAN,tr|E2QRB3|E2QRB3_HUMAN,tr|J3KQ22|J3KQ22_HUMAN" 4 2320.156 0.9 90804 24188 4 2320.154593 581.0463 "Pyrroline-5-carboxylate reductase 1, mitochondrial OS=Homo sapiens OX=9606 GN=PYCR1 PE=1 SV=2" 5.99 3671.8 - 760835 - - - -0.6094 - 3.738 0.642 - 365.8 1 2 0 -0.0014 23 0 0 0 6.99E+07 7.80E+07 - - - 5.2408 0.9997 221125_WJC_METTL3_EV_vs_WT_F06.24194.24194.4 3.68E-06 14/108 R.GLLQDDAHPTLVTYADHSK[136.11].L "sp|Q86U44|MTA70_HUMAN,tr|F5H6D8|F5H6D8_HUMAN,tr|H0YFV6|H0YFV6_HUMAN,tr|B4DTN4|B4DTN4_HUMAN" 4 2088.0367 0.01 90808 24194 4 2088.029764 523.0165 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 5.13 3672.6 - 832837 - - - -3.3376 - 2.875 0.44 - 126.9 1 2 0 -0.007 19 0 0 0 1.95E+05 2.28E+07 - - - 3.4111 0.9996 221125_WJC_METTL3_EV_vs_WT_F06.24197.24197.3 2.55E-07 19/76 K.HAASDVDLEIESLLNQQSTK[136.11].E "sp|Q86U44|MTA70_HUMAN,tr|F5H6D8|F5H6D8_HUMAN,tr|H0YFV6|H0YFV6_HUMAN,tr|B4DTN4|B4DTN4_HUMAN" 4 2205.1005 0.07 90811 24197 3 2206.100511 736.0408 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 4.31 3672.9 - 3.30E+06 - - - 453.519 - 4.13 0.605 - 435.4 1 2 0 1.0001 20 0 0 0 1.45E+07 2.02E+08 - - - 8.4489 1 221125_WJC_METTL3_EV_vs_WT_F06.24199.24199.3 1.94E-06 17/64 R.IQEIIEQLDVTTSEYEK.E "sp|P10809|CH60_HUMAN,tr|A0A7I2V2X6|A0A7I2V2X6_HUMAN,tr|A0A7I2YQK6|A0A7I2YQK6_HUMAN,tr|A0A7I2V599|A0A7I2V599_HUMAN" 4 2037.0154 1.54 90813 24199 3 2037.016161 680.0124 "60 kDa heat shock protein, mitochondrial OS=Homo sapiens OX=9606 GN=HSPD1 PE=1 SV=2" 3.91 3673.1 - 824016 - - - 0.3824 - 3.064 0.493 - 436.9 1 2 0 0.0008 17 0 0 0 1.71E+07 1.11E+07 - - - 6.865 1 221125_WJC_METTL3_EV_vs_WT_F06.24204.24204.2 2.88E-09 21/30 K.K[136.11]VSQEILELLNTTTAK[136.11].E "sp|Q86U44|MTA70_HUMAN,tr|H0YFV6|H0YFV6_HUMAN" 2 1803.0324 0 90816 24204 2 1803.028164 902.5235 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 6.14 3673.7 - 6.36E+06 - - - -2.366 - 4.241 0.679 - 1237.7 1 2 0 -0.0043 16 0 0 0 2.70E+05 2.30E+09 - - - 7.6069 1 221125_WJC_METTL3_EV_vs_WT_F06.24213.24213.2 1.33E-10 19/32 R.IQEIIEQLDVTTSEYEK.E "sp|P10809|CH60_HUMAN,tr|A0A7I2V2X6|A0A7I2V2X6_HUMAN,tr|A0A7I2YQK6|A0A7I2YQK6_HUMAN,tr|A0A7I2V599|A0A7I2V599_HUMAN" 4 2037.0154 1.49 90820 24213 2 2037.013909 1019.515 "60 kDa heat shock protein, mitochondrial OS=Homo sapiens OX=9606 GN=HSPD1 PE=1 SV=2" 3.91 3674.9 - 503589 - - - -0.7231 - 3.809 0.644 - 1014.4 1 2 0 -0.0015 17 0 0 0 4.46E+06 2.99E+06 - - - 7.0851 1 221125_WJC_METTL3_EV_vs_WT_F06.24215.24215.4 3.96E-16 23/126 R.HHYESFQDDEGASMLILLDNAK.S sp|O75063|XYLK_HUMAN 1 2532.1591 1.18 90822 24215 4 2532.156887 634.0471 Glycosaminoglycan xylosylkinase OS=Homo sapiens OX=9606 GN=FAM20B PE=1 SV=1 4.42 3675.2 - 629324 - - - -0.8751 - 4.189 0.73 - 491.8 1 2 0 -0.0022 22 0 0 0 1.16E+07 9.84E+06 - - - 6.048 1 221125_WJC_METTL3_EV_vs_WT_F06.24228.24228.3 7.52E-05 15/64 R.IQEIIEQLDVTTSEYEK[136.11].E "sp|P10809|CH60_HUMAN,tr|A0A7I2V2X6|A0A7I2V2X6_HUMAN,tr|A0A7I2YQK6|A0A7I2YQK6_HUMAN,tr|A0A7I2V599|A0A7I2V599_HUMAN" 4 2045.0296 1.54 90828 24228 3 2045.028475 682.6838 "60 kDa heat shock protein, mitochondrial OS=Homo sapiens OX=9606 GN=HSPD1 PE=1 SV=2" 3.91 3676.9 - 420439 - - - -0.5413 - 2.938 0.47 - 390.5 1 2 0 -0.0011 17 0 0 0 1.71E+07 1.11E+07 - - - 6.5024 0.9697 221125_WJC_METTL3_EV_vs_WT_F06.24235.24235.2 2.39E-06 19/30 K.K[136.11]VSQEILELLNTTTAK.E "sp|Q86U44|MTA70_HUMAN,tr|H0YFV6|H0YFV6_HUMAN" 2 1795.0182 - 90831 24235 2 1796.014948 898.5164 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 6.14 3677.9 - 930710 - - - 555.269 - 3.057 0.502 - 869.9 1 2 0 0.9967 16 0 0 0 - - - - - 5.1831 1 221125_WJC_METTL3_EV_vs_WT_F06.24240.24240.3 2.26E-08 20/68 K.ISSIQSIVPALEIANAHR.K "sp|P10809|CH60_HUMAN,tr|A0A7I2V2X6|A0A7I2V2X6_HUMAN,tr|A0A7I2YQK6|A0A7I2YQK6_HUMAN,tr|A0A7I2V599|A0A7I2V599_HUMAN,tr|A0A7I2YQ71|A0A7I2YQ71_HUMAN,tr|A0A7I2V5M1|A0A7I2V5M1_HUMAN,tr|A0A7I2V5K3|A0A7I2V5K3_HUMAN,tr|A0A7I2V369|A0A7I2V369_HUMAN" 8 1918.0636 1.29 90834 24240 3 1918.061705 640.3618 "60 kDa heat shock protein, mitochondrial OS=Homo sapiens OX=9606 GN=HSPD1 PE=1 SV=2" 6.75 3678.5 - 4.27E+06 - - - -0.9932 - 3.319 0.483 - 415.4 1 2 0 -0.0019 18 0 0 0 2.17E+08 1.68E+08 - - - 6.9117 1 221125_WJC_METTL3_EV_vs_WT_F06.24246.24246.3 4.58E-11 19/132 R.DSPAVSLSEPATQQASLDVEKPVGVAASLSDIPK.A "sp|Q14687|GSE1_HUMAN,tr|H7C3B5|H7C3B5_HUMAN" 2 3405.7515 15.66 90836 24246 3 3405.744354 1136.2578 Genetic suppressor element 1 OS=Homo sapiens OX=9606 GN=GSE1 PE=1 SV=3 4.11 3679.3 - 730195 - - - -2.1014 - 3.845 0.631 - 171.9 1 2 0 -0.0072 34 0 0 0 1.67E+07 1.07E+06 - - - 8.6715 0.9985 221125_WJC_METTL3_EV_vs_WT_F06.24253.24253.4 2.54E-09 36/234 K.VVGSAVGSGSITSNIVASNSLPPATIAPPKPASWADIASK.P sp|Q9Y5A9|YTHD2_HUMAN 1 3817.0262 1.93 90840 24253 4 3817.025695 955.2638 YTH domain-containing family protein 2 OS=Homo sapiens OX=9606 GN=YTHDF2 PE=1 SV=2 8.56 3680.2 - 1.13E+06 - - - -0.1242 - 5.521 0.609 - 295.7 1 1 0 -0.0005 40 0 0 0 8.42E+07 4.36E+07 - - - 5.0198 1 221125_WJC_METTL3_EV_vs_WT_F06.24256.24256.3 2.23E-12 17/88 R.ESNTPAPSTQGLPDSWGIIAEPR[166.11].Q "sp|O14654|IRS4_HUMAN,tr|A0A804CF45|A0A804CF45_HUMAN" 2 2432.1847 2.89 90843 24256 3 2432.177291 811.7355 Insulin receptor substrate 4 OS=Homo sapiens OX=9606 GN=IRS4 PE=1 SV=1 4.14 3680.6 - 425877 - - - -3.0619 - 3.242 0.663 - 315.1 1 2 0 -0.0074 23 0 0 0 1.92E+07 6.66E+06 - - - 8.689 1 221125_WJC_METTL3_EV_vs_WT_F06.24267.24267.3 2.33E-08 20/100 R.KAELMGISTDIFPVDNSDTSSSVDGR.R "sp|O94880|PHF14_HUMAN,tr|B4DG57|B4DG57_HUMAN,tr|A0A0U1RRH6|A0A0U1RRH6_HUMAN" 3 2740.2862 4.19 90848 24267 3 2740.288707 914.436 PHD finger protein 14 OS=Homo sapiens OX=9606 GN=PHF14 PE=1 SV=2 4.04 3681.8 - 712769 - - - 0.9313 - 3.979 0.698 - 284.3 1 2 0 0.0026 26 0 0 0 1.81E+07 4.32E+06 - - - 9.4986 0.9999 221125_WJC_METTL3_EV_vs_WT_F06.24269.24269.4 3.36E-07 27/144 K.ELTTEIDNNIEQISSYKSEITELRR.N "sp|P13645|K1C10_HUMAN,tr|A0A1B0GVI3|A0A1B0GVI3_HUMAN" 2 2980.4989 28.76 90849 24269 4 2980.499712 746.132 "Keratin, type I cytoskeletal 10 OS=Homo sapiens OX=9606 GN=KRT10 PE=1 SV=6" 4.42 3682 - 2.40E+06 - - - 0.264 - 3.63 0.581 - 391.6 1 2 1 0.0008 25 0 0 0 2.24E+08 7.79E+06 - - - 4.6929 1 221125_WJC_METTL3_EV_vs_WT_F06.24281.24281.3 1.78E-16 22/124 K.VTDETSGC[160.03]SLTC[160.03]AQFHPDGLIFGTGTMDSQIK.L "sp|Q9UMS4|PRP19_HUMAN,tr|H0YGZ5|H0YGZ5_HUMAN" 2 3472.5585 1.56 90854 24281 3 3472.552354 1158.5268 Pre-mRNA-processing factor 19 OS=Homo sapiens OX=9606 GN=PRPF19 PE=1 SV=1 4.22 3683.6 - 1.63E+06 - - - -1.7719 - 4.608 0.747 - 339.9 1 2 0 -0.0062 32 0 0 0 5.54E+07 3.55E+07 - - - 10.3815 1 221125_WJC_METTL3_EV_vs_WT_F06.24287.24287.3 3.76E-08 Nov-48 K.C[160.03]EFQDAYVLLSEK.K "sp|P10809|CH60_HUMAN,tr|A0A7I2V2X6|A0A7I2V2X6_HUMAN,tr|A0A7I2YQK6|A0A7I2YQK6_HUMAN,tr|A0A7I2V599|A0A7I2V599_HUMAN,tr|A0A7I2YQ71|A0A7I2YQ71_HUMAN,tr|A0A7I2V5M1|A0A7I2V5M1_HUMAN,tr|A0A7I2V5K3|A0A7I2V5K3_HUMAN,tr|A0A7I2V369|A0A7I2V369_HUMAN" 8 1600.7443 1.67 90858 24287 3 1600.743883 534.5887 "60 kDa heat shock protein, mitochondrial OS=Homo sapiens OX=9606 GN=HSPD1 PE=1 SV=2" 4.14 3684.3 - 306444 - - - -0.2668 - 2.16 0.58 - 141.9 1 2 0 -0.0004 13 0 0 0 9.31E+06 5.58E+06 - - - 7.0943 1 221125_WJC_METTL3_EV_vs_WT_F06.24288.24288.4 1.39E-07 17/90 K.K[136.11]VSQEILELLNTTTAK[136.11].E "sp|Q86U44|MTA70_HUMAN,tr|H0YFV6|H0YFV6_HUMAN" 2 1803.0324 0.001 90859 24288 4 1803.02818 451.7654 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 6.14 3684.4 - 361207 - - - -2.3571 - 3.341 0.554 - 343.1 1 2 0 -0.0043 16 0 0 0 0.00E+00 1.42E+07 - - - 4.4718 0.8406 221125_WJC_METTL3_EV_vs_WT_F06.24292.24292.3 0.000664 Dec-92 R.NGPGFHNDIDSNSTIQEILIPASK[136.11].V sp|Q96I24|FUBP3_HUMAN 1 2574.2805 0.57 90860 24292 3 2575.26481 859.1008 Far upstream element-binding protein 3 OS=Homo sapiens OX=9606 GN=FUBP3 PE=1 SV=2 4.54 3685 - 1.35E+06 - - - 382.3453 - 2.53 0.447 - 77.3 1 2 0 0.9843 24 0 0 0 2.78E+06 4.85E+06 - - - 5.4068 1 221125_WJC_METTL3_EV_vs_WT_F06.24302.24302.4 3.04E-09 23/138 R.TC[160.03]EEHQLC[160.03]VVAVLPHILDTGAAGR.N sp|Q15084|PDIA6_HUMAN 1 2645.3054 1.49 90865 24302 4 2645.310664 662.3336 Protein disulfide-isomerase A6 OS=Homo sapiens OX=9606 GN=PDIA6 PE=1 SV=1 5.26 3686.2 - 837915 - - - 1.9933 - 3.837 0.644 - 447.1 1 2 0 0.0053 24 0 0 0 1.38E+08 9.29E+07 - - - 5.2615 1 221125_WJC_METTL3_EV_vs_WT_F06.24304.24304.3 2.84E-15 25/124 K.VTDETSGC[160.03]SLTC[160.03]AQFHPDGLIFGTGTMDSQIK[136.11].L "sp|Q9UMS4|PRP19_HUMAN,tr|H0YGZ5|H0YGZ5_HUMAN" 2 3480.5727 1.56 90866 24304 3 3480.567724 1161.1982 Pre-mRNA-processing factor 19 OS=Homo sapiens OX=9606 GN=PRPF19 PE=1 SV=1 4.22 3686.4 - 860825 - - - -1.4317 - 4.622 0.757 - 444.3 1 2 0 -0.005 32 0 0 0 5.54E+07 3.55E+07 - - - 10.5003 1 221125_WJC_METTL3_EV_vs_WT_F06.24306.24306.4 3.59E-08 20/102 R.SHTEEDC[160.03]TEELFDFLHAR[166.11].D sp|P07919|QCR6_HUMAN 1 2244.9621 1.32 90867 24306 4 2244.962327 562.2478 "Cytochrome b-c1 complex subunit 6, mitochondrial OS=Homo sapiens OX=9606 GN=UQCRH PE=1 SV=2" 4.35 3686.7 - 544008 - - - 0.0869 - 3.63 0.677 - 488.4 1 2 0 0.0002 18 0 0 0 2.16E+08 1.63E+08 - - - 5.5602 1 221125_WJC_METTL3_EV_vs_WT_F06.24308.24308.4 2.88E-09 24/102 R.SHTEEDC[160.03]TEELFDFLHAR.D sp|P07919|QCR6_HUMAN 1 2234.9539 1.32 90868 24308 4 2234.956503 559.7457 "Cytochrome b-c1 complex subunit 6, mitochondrial OS=Homo sapiens OX=9606 GN=UQCRH PE=1 SV=2" 4.35 3686.9 - 487337 - - - 1.1817 - 3.862 0.715 - 812.2 1 2 0 0.0026 18 0 0 0 2.16E+08 1.64E+08 - - - 5.9115 1 221125_WJC_METTL3_EV_vs_WT_F06.24319.24319.3 2.61E-10 17/92 K.QTQTFTTYSDNQPGVLIQVYEGER[166.11].A "sp|P11142|HSP7C_HUMAN,tr|E9PNE6|E9PNE6_HUMAN,tr|A8K7Q2|A8K7Q2_HUMAN,tr|E9PKE3|E9PKE3_HUMAN,tr|E9PS65|E9PS65_HUMAN" 5 2783.3278 0.13 90873 24319 3 2783.331701 928.7832 Heat shock cognate 71 kDa protein OS=Homo sapiens OX=9606 GN=HSPA8 PE=1 SV=1 4.14 3688.2 - 627630 - - - 1.4109 - 3.325 0.611 - 256.9 1 2 0 0.0039 24 0 0 0 6.97E+07 5.42E+08 - - - 8.1415 0.9785 221125_WJC_METTL3_EV_vs_WT_F06.24323.24323.4 0.00137 16/126 R.K[136.11]IELFGR[166.11]PHNVQPNWITLGNQL.D sp|Q86U44|MTA70_HUMAN 1 2591.4091 0.05 90875 24323 4 2591.40925 648.8596 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 8.75 3688.7 - 1.14E+06 - - - 0.0401 - 2.811 0.378 - 124.7 1 1 0 0.0001 22 0 0 0 4.45E+06 8.36E+07 - - - 2.8543 1 221125_WJC_METTL3_EV_vs_WT_F06.24326.24326.3 2.76E-11 24/68 R.SHTEEDC[160.03]TEELFDFLHAR[166.11].D sp|P07919|QCR6_HUMAN 1 2244.9621 1.4 90878 24326 3 2244.957674 749.328 "Cytochrome b-c1 complex subunit 6, mitochondrial OS=Homo sapiens OX=9606 GN=UQCRH PE=1 SV=2" 4.35 3689.1 - 651007 - - - -1.9858 - 4.204 0.752 - 893.2 1 2 0 -0.0045 18 0 0 0 1.18E+08 8.40E+07 - - - 10.4987 1 221125_WJC_METTL3_EV_vs_WT_F06.24329.24329.4 8.98E-13 25/132 R.GFAYVQFEDVRDAEDALHNLDRK.W "sp|O75494|SRS10_HUMAN,tr|Q5JRI1|Q5JRI1_HUMAN" 2 2707.299 2.24 90879 24329 4 2707.298854 677.832 Serine\arginine-rich splicing factor 10 OS=Homo sapiens OX=9606 GN=SRSF10 PE=1 SV=1 4.52 3689.5 - 2.53E+06 - - - -0.0698 - 4.266 0.649 - 499 1 2 1 -0.0002 23 0 0 0 5.92E+07 2.64E+07 - - - 5.3448 0.9998 221125_WJC_METTL3_EV_vs_WT_F06.24330.24330.4 1.63E-08 27/150 R.SFGTEDRPTDRPIPPRDEVFEYIIFR.G "sp|Q8ND56|LS14A_HUMAN,tr|I3L4Q1|I3L4Q1_HUMAN,tr|A0A140TA76|A0A140TA76_HUMAN,tr|K7EMZ9|K7EMZ9_HUMAN" 4 3151.5727 1.04 90880 24330 4 3151.580766 788.9005 Protein LSM14 homolog A OS=Homo sapiens OX=9606 GN=LSM14A PE=1 SV=3 4.59 3689.6 - 2.99E+06 - - - 2.5597 - 3.384 0.534 - 134.8 1 2 1 0.0081 26 0 0 0 7.13E+09 6.82E+09 - - - 4.2562 1 221125_WJC_METTL3_EV_vs_WT_F06.24335.24335.4 3.93E-11 27/138 R.TC[160.03]EEHQLC[160.03]VVAVLPHILDTGAAGR[166.11].N sp|Q15084|PDIA6_HUMAN 1 2655.3137 1.49 90882 24335 4 2655.313959 664.8357 Protein disulfide-isomerase A6 OS=Homo sapiens OX=9606 GN=PDIA6 PE=1 SV=1 5.26 3690.5 - 1.27E+06 - - - 0.1122 - 4.006 0.687 - 584 1 2 0 0.0003 24 0 0 0 1.38E+08 9.27E+07 - - - 5.651 1 221125_WJC_METTL3_EV_vs_WT_F06.24337.24337.4 8.31E-19 54/198 K.LHEEEIQELQAQIQEQHVQIDVDVSKPDLTAALR.D "sp|P08670|VIME_HUMAN,tr|B0YJC5|B0YJC5_HUMAN,tr|B0YJC4|B0YJC4_HUMAN" 3 3922.0072 2.51 90883 24337 4 3922.003936 981.5091 Vimentin OS=Homo sapiens OX=9606 GN=VIM PE=1 SV=4 4.32 3690.7 - 2.69E+06 - - - -0.8386 - 8.647 0.757 - 1209 1 2 0 -0.0033 34 0 0 0 1.25E+09 5.00E+08 - - - 6.4573 1 221125_WJC_METTL3_EV_vs_WT_F06.24342.24342.3 1.03E-05 27/52 K.KQELEEILHDLESR.V sp|P35580|MYH10_HUMAN 1 1737.8897 0.93 90886 24342 3 1737.88594 580.3039 Myosin-10 OS=Homo sapiens OX=9606 GN=MYH10 PE=1 SV=3 4.57 3691.3 - 1.60E+06 - - - -2.1797 - 4.554 0.531 - 1736.3 1 2 0 -0.0038 14 0 0 0 4.54E+08 4.88E+08 - - - 8.4879 1 221125_WJC_METTL3_EV_vs_WT_F06.24343.24343.3 4.64E-05 16/60 K.K[136.11]VSQEILELLNTTTAK.E "sp|Q86U44|MTA70_HUMAN,tr|H0YFV6|H0YFV6_HUMAN" 2 1795.0182 - 90887 24343 3 1795.017378 599.3467 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 6.14 3691.4 - 1.81E+06 - - - -0.4746 - 3.101 0.436 - 489.2 2 2 0 -0.0009 16 0 0 0 - - - - - 6.1653 0.999 221125_WJC_METTL3_EV_vs_WT_F06.24344.24344.4 1.69E-07 16/78 K.K[136.11]QELEEILHDLESR[166.11].V sp|P35580|MYH10_HUMAN 1 1755.9122 0.93 90888 24344 4 1755.907594 439.9853 Myosin-10 OS=Homo sapiens OX=9606 GN=MYH10 PE=1 SV=3 4.57 3691.5 - 555477 - - - -2.622 - 3.011 0.322 - 323.8 1 2 0 -0.0046 14 0 0 0 8.76E+07 9.39E+07 - - - 2.4286 1 221125_WJC_METTL3_EV_vs_WT_F06.24348.24348.3 6.79E-09 27/52 K.K[136.11]QELEEILHDLESR[166.11].V sp|P35580|MYH10_HUMAN 1 1755.9122 0.93 90890 24348 3 1755.908762 586.3113 Myosin-10 OS=Homo sapiens OX=9606 GN=MYH10 PE=1 SV=3 4.57 3692 - 2.21E+06 - - - -1.9568 - 4.171 0.522 - 1649.6 1 2 0 -0.0034 14 0 0 0 4.54E+08 4.88E+08 - - - 8.1542 1 221125_WJC_METTL3_EV_vs_WT_F06.24351.24351.4 4.03E-12 29/174 R.FHEFHSPALEDADFENKPMILLVGQYSTGK.T sp|Q9H223|EHD4_HUMAN 1 3419.6496 2.13 90891 24351 4 3419.637575 855.9197 EH domain-containing protein 4 OS=Homo sapiens OX=9606 GN=EHD4 PE=1 SV=1 4.87 3692.4 - 1.61E+06 - - - -3.5246 - 3.071 0.688 - 143.2 1 2 0 -0.0121 30 0 0 0 2.16E+07 1.02E+07 - - - 5.5544 0.9984 221125_WJC_METTL3_EV_vs_WT_F06.24354.24354.3 0.000165 13/100 R.SFGTEDRPTDRPIPPRDEVFEYIIFR.G "sp|Q8ND56|LS14A_HUMAN,tr|I3L4Q1|I3L4Q1_HUMAN,tr|A0A140TA76|A0A140TA76_HUMAN,tr|K7EMZ9|K7EMZ9_HUMAN" 4 3151.5727 1.54 90893 24354 3 3151.567354 1051.5315 Protein LSM14 homolog A OS=Homo sapiens OX=9606 GN=LSM14A PE=1 SV=3 4.59 3692.7 - 3.26E+06 - - - -1.696 - 1.563 0.436 - 40.3 1 2 1 -0.0053 26 0 0 0 4.56E+08 2.96E+08 - - - 4.427 1 221125_WJC_METTL3_EV_vs_WT_F06.24359.24359.3 2.01E-19 28/68 R.SHTEEDC[160.03]TEELFDFLHAR.D sp|P07919|QCR6_HUMAN 1 2234.9539 1.4 90895 24359 3 2234.950235 745.9919 "Cytochrome b-c1 complex subunit 6, mitochondrial OS=Homo sapiens OX=9606 GN=UQCRH PE=1 SV=2" 4.35 3693.3 - 1.67E+06 - - - -1.6229 - 4.892 0.782 - 1288.8 1 2 0 -0.0036 18 0 0 0 1.18E+08 8.40E+07 - - - 11.2108 1 221125_WJC_METTL3_EV_vs_WT_F06.24361.24361.4 1.13E-12 28/174 K.ANEFHDVNC[160.03]EVVAVSVDSHFSHLAWINTPR[166.11].K sp|P30048|PRDX3_HUMAN 1 3459.6294 0.49 90896 24361 4 3459.619827 865.9146 "Thioredoxin-dependent peroxide reductase, mitochondrial OS=Homo sapiens OX=9606 GN=PRDX3 PE=1 SV=3" 5.21 3693.5 - 2.00E+06 - - - -2.7647 - 4.194 0.649 - 113.6 1 2 0 -0.0096 30 0 0 0 1.06E+07 2.18E+07 - - - 5.311 0.9999 221125_WJC_METTL3_EV_vs_WT_F06.24365.24365.4 1.37E-06 21/78 K.KQELEEILHDLESR.V sp|P35580|MYH10_HUMAN 1 1737.8897 0.93 90898 24365 4 1737.88511 435.4797 Myosin-10 OS=Homo sapiens OX=9606 GN=MYH10 PE=1 SV=3 4.57 3694.1 - 1.35E+06 - - - -2.6572 - 3.498 0.532 - 569 1 2 0 -0.0046 14 0 0 0 8.76E+07 9.39E+07 - - - 4.311 1 221125_WJC_METTL3_EV_vs_WT_F06.24369.24369.3 8.78E-25 45/132 K.LHEEEIQELQAQIQEQHVQIDVDVSKPDLTAALR.D "sp|P08670|VIME_HUMAN,tr|B0YJC5|B0YJC5_HUMAN,tr|B0YJC4|B0YJC4_HUMAN" 3 3922.0072 7.19 90899 24369 3 3921.995085 1308.343 Vimentin OS=Homo sapiens OX=9606 GN=VIM PE=1 SV=4 4.32 3694.6 - 1.57E+06 - - - -3.0954 - 6.934 0.776 - 2428.3 1 2 0 -0.0121 34 0 0 0 4.79E+07 6.67E+06 - - - 11.6433 1 221125_WJC_METTL3_EV_vs_WT_F06.24388.24388.4 1.01E-18 38/174 R.HIADLAGNSEVILPVPAFNVINGGSHAGNK.L "sp|P06733|ENOA_HUMAN,tr|A0A2R8Y6G6|A0A2R8Y6G6_HUMAN,tr|K7EM90|K7EM90_HUMAN,tr|A0A2R8YEM5|A0A2R8YEM5_HUMAN" 4 3010.5625 1.57 90903 24388 4 3010.560146 753.6479 Alpha-enolase OS=Homo sapiens OX=9606 GN=ENO1 PE=1 SV=2 5.99 3697.4 - 2.26E+06 - - - -0.7713 - 6.055 0.706 - 987.8 1 2 0 -0.0023 30 0 0 0 2.67E+08 1.70E+08 - - - 5.9215 0.9999 221125_WJC_METTL3_EV_vs_WT_F06.24392.24392.3 1.14E-05 17/68 K.YVHYEIDAC[160.03]MDSEAPGSK[136.11].D "sp|Q86U44|MTA70_HUMAN,tr|H0YFV6|H0YFV6_HUMAN" 2 2078.8805 0 90905 24392 3 2078.871197 693.9674 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 4.31 3697.9 - 691508 - - - -4.4712 - 3.075 0.573 - 280.7 1 2 0 -0.0093 18 0 0 0 3.39E+05 7.24E+07 - - - 7.723 0.9992 221125_WJC_METTL3_EV_vs_WT_F06.24402.24402.4 4.88E-05 19/234 R.ASPATQPPPLLPPSATGPDATVGGPAPTPLLPPSATASVK.M sp|Q07666|KHDR1_HUMAN 1 3725.988 2.29 90911 24402 4 3725.972184 932.5043 "KH domain-containing, RNA-binding, signal transduction-associated protein 1 OS=Homo sapiens OX=9606 GN=KHDRBS1 PE=1 SV=1" 5.88 3699.2 - 1.15E+06 - - - -4.2429 - 2.29 0.427 - 66.3 1 2 0 -0.0158 40 0 0 0 3.98E+07 1.74E+07 - - - 3.1774 1 221125_WJC_METTL3_EV_vs_WT_F06.24410.24410.4 2.58E-12 38/174 R.HIADLAGNSEVILPVPAFNVINGGSHAGNK[136.11].L "sp|P06733|ENOA_HUMAN,tr|A0A2R8Y6G6|A0A2R8Y6G6_HUMAN,tr|K7EM90|K7EM90_HUMAN,tr|A0A2R8YEM5|A0A2R8YEM5_HUMAN" 4 3018.5767 1.61 90915 24410 4 3018.574005 755.6514 Alpha-enolase OS=Homo sapiens OX=9606 GN=ENO1 PE=1 SV=2 5.99 3700.2 - 5.20E+06 - - - -0.8822 - 5.712 0.64 - 799.3 1 2 0 -0.0027 30 0 0 0 2.67E+08 1.66E+08 - - - 5.3291 1 221125_WJC_METTL3_EV_vs_WT_F06.24412.24412.3 3.47E-12 19/92 R.EQNKPDSSPLYIQNPFETSLNISK.N sp|Q9NVV4|PAPD1_HUMAN 1 2748.3606 0.38 90916 24412 3 2748.353804 917.1275 "Poly(A) RNA polymerase, mitochondrial OS=Homo sapiens OX=9606 GN=MTPAP PE=1 SV=1" 4.68 3700.6 - 1.19E+06 - - - -2.4873 - 4.14 0.626 - 330.5 1 2 0 -0.0068 24 0 0 0 2.93E+07 7.69E+07 - - - 8.8171 1 221125_WJC_METTL3_EV_vs_WT_F06.24418.24418.3 1.22E-07 22/92 K.QTQTFTTYSDNQPGVLIQVYEGER.A "sp|P11142|HSP7C_HUMAN,tr|E9PNE6|E9PNE6_HUMAN,tr|A8K7Q2|A8K7Q2_HUMAN,tr|E9PKE3|E9PKE3_HUMAN,tr|E9PS65|E9PS65_HUMAN" 5 2773.3195 0.13 90919 24418 3 2773.32212 925.4471 Heat shock cognate 71 kDa protein OS=Homo sapiens OX=9606 GN=HSPA8 PE=1 SV=1 4.14 3701.4 - 1.67E+06 - - - 0.9433 - 3.503 0.654 - 426.1 1 2 0 0.0026 24 0 0 0 6.81E+07 5.39E+08 - - - 8.7424 1 221125_WJC_METTL3_EV_vs_WT_F06.24419.24419.4 1.06E-08 23/156 K.DLPRPSEVNETILRPLNVEPPLTDLQK.S sp|Q99459|CDC5L_HUMAN 1 3082.6663 1.6 90920 24419 4 3082.666773 771.6738 Cell division cycle 5-like protein OS=Homo sapiens OX=9606 GN=CDC5L PE=1 SV=2 4.51 3701.5 - 1.32E+06 - - - 0.1648 - 3.903 0.485 - 285.8 1 2 0 0.0005 27 0 0 0 6.57E+07 4.10E+07 - - - 3.8734 1 221125_WJC_METTL3_EV_vs_WT_F06.24422.24422.4 5.32E-12 30/174 R.LKETDQILAINGQALDQTITHQQAISILQK.A "sp|O75970|MPDZ_HUMAN,tr|F5H1U9|F5H1U9_HUMAN" 2 3330.8147 1.57 90921 24422 4 3330.818914 833.711 Multiple PDZ domain protein OS=Homo sapiens OX=9606 GN=MPDZ PE=1 SV=2 5.38 3701.9 - 1.57E+06 - - - 1.2592 - 5.32 0.652 - 602.6 1 2 1 0.0042 30 0 0 0 9.50E+06 6.04E+06 - - - 5.4113 0.9986 221125_WJC_METTL3_EV_vs_WT_F06.24423.24423.4 2.17E-05 22/174 R.LK[136.11]ETDQILAINGQALDQTITHQQAISILQK[136.11].A "sp|O75970|MPDZ_HUMAN,tr|F5H1U9|F5H1U9_HUMAN" 2 3346.8431 1.57 90922 24423 4 3346.825698 837.7181 Multiple PDZ domain protein OS=Homo sapiens OX=9606 GN=MPDZ PE=1 SV=2 5.38 3702 - 859373 - - - -5.2055 - 3.069 0.545 - 183 1 2 1 -0.0174 30 0 0 0 9.50E+06 6.04E+06 - - - 4.308 1 221125_WJC_METTL3_EV_vs_WT_F06.24424.24424.3 1.40E-08 21/60 K.K[136.11]VSQEILELLNTTTAK[136.11].E "sp|Q86U44|MTA70_HUMAN,tr|H0YFV6|H0YFV6_HUMAN" 2 1803.0324 0.01 90923 24424 3 1803.028332 602.0181 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 6.14 3702.1 - 1.23E+06 - - - -2.2728 - 4.165 0.655 - 821.7 1 2 0 -0.0041 16 0 0 0 9.94E+07 1.47E+10 - - - 9.5022 0.9903 221125_WJC_METTL3_EV_vs_WT_F06.24429.24429.4 0.000976 26/204 F.GSK[136.11]PAPGTLGTGLGAGFGTALGAGQASLFGNNQPK[136.11].L "sp|P52948|NUP98_HUMAN,tr|A0A3B3ITD8|A0A3B3ITD8_HUMAN,tr|H0YEN4|H0YEN4_HUMAN" 3 3214.6706 2.25 90926 24429 4 3214.676986 804.6749 Nuclear pore complex protein Nup98-Nup96 OS=Homo sapiens OX=9606 GN=NUP98 PE=1 SV=4 10 3702.7 - 1.89E+06 - - - 1.9943 - 4.754 0.451 - 217.9 1 1 0 0.0064 35 0 0 0 2.66E+07 1.18E+07 - - - 3.6119 1 221125_WJC_METTL3_EV_vs_WT_F06.24430.24430.4 6.87E-07 27/156 K.DLPR[166.11]PSEVNETILR[166.11]PLNVEPPLTDLQK[136.11].S sp|Q99459|CDC5L_HUMAN 1 3110.697 1.69 90927 24430 4 3110.69393 778.6815 Cell division cycle 5-like protein OS=Homo sapiens OX=9606 GN=CDC5L PE=1 SV=2 4.51 3702.9 - 1.63E+06 - - - -0.9885 - 3.379 0.55 - 366.2 1 2 0 -0.0031 27 0 0 0 6.55E+07 3.87E+07 - - - 4.3933 1 221125_WJC_METTL3_EV_vs_WT_F06.24431.24431.3 3.66E-06 40/116 R.HIADLAGNSEVILPVPAFNVINGGSHAGNK.L "sp|P06733|ENOA_HUMAN,tr|A0A2R8Y6G6|A0A2R8Y6G6_HUMAN,tr|K7EM90|K7EM90_HUMAN,tr|A0A2R8YEM5|A0A2R8YEM5_HUMAN" 4 3010.5625 2.59 90928 24431 3 3010.560692 1004.5281 Alpha-enolase OS=Homo sapiens OX=9606 GN=ENO1 PE=1 SV=2 5.99 3703 - 1.52E+06 - - - -0.5899 - 5.95 0.669 - 1622.8 1 2 0 -0.0018 30 0 0 0 2.63E+07 1.01E+07 - - - 10.1011 0.9999 221125_WJC_METTL3_EV_vs_WT_F06.24433.24433.4 2.95E-05 12/108 R.GLLQDDAHPTLVTYADHSK[136.11].L "sp|Q86U44|MTA70_HUMAN,tr|F5H6D8|F5H6D8_HUMAN,tr|H0YFV6|H0YFV6_HUMAN,tr|B4DTN4|B4DTN4_HUMAN" 4 2088.0367 0.05 90929 24433 4 2088.03444 523.0165 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 5.13 3703.2 - 1.44E+06 - - - -1.0982 - 2.643 0.468 - 120 1 2 0 -0.0023 19 0 0 0 1.78E+06 3.59E+07 - - - 3.6276 0.9999 221125_WJC_METTL3_EV_vs_WT_F06.24436.24436.3 1.92E-06 22/76 K.NNQFQALLQYADPVSAQHAK[136.11].L "sp|P26599|PTBP1_HUMAN,tr|A0A6Q8PEX4|A0A6Q8PEX4_HUMAN,tr|A0A0U1RRM4|A0A0U1RRM4_HUMAN,tr|A6NLN1|A6NLN1_HUMAN,tr|K7EKJ7|K7EKJ7_HUMAN,tr|A0A087WU68|A0A087WU68_HUMAN,tr|A0A7I2V4H6|A0A7I2V4H6_HUMAN,tr|A0A7I2V621|A0A7I2V621_HUMAN,tr|K7EK45|K7EK45_HUMAN" 9 2250.1273 1.37 90931 24436 3 2250.119558 751.0497 Polypyrimidine tract-binding protein 1 OS=Homo sapiens OX=9606 GN=PTBP1 PE=1 SV=1 6.74 3703.5 - 1.34E+06 - - - -3.4318 - 3.534 0.528 - 411.3 1 2 0 -0.0077 20 0 0 0 2.42E+08 1.77E+08 - - - 7.4872 1 221125_WJC_METTL3_EV_vs_WT_F06.24437.24437.3 5.50E-09 27/100 K.ITVTFNINNSIPPTFDGEEEPSQGQK[136.11].V "sp|Q07021|C1QBP_HUMAN,tr|I3L3B0|I3L3B0_HUMAN,tr|I3L3Q7|I3L3Q7_HUMAN" 3 2869.3861 1.27 90932 24437 3 2869.38333 957.4693 "Complement component 1 Q subcomponent-binding protein, mitochondrial OS=Homo sapiens OX=9606 GN=C1QBP PE=1 SV=1" 4 3703.6 - 2.22E+06 - - - -0.9769 - 3.804 0.603 - 494.1 1 2 0 -0.0028 26 0 0 0 1.31E+08 1.03E+08 - - - 8.3359 1 221125_WJC_METTL3_EV_vs_WT_F06.24441.24441.3 6.24E-10 23/100 K.ITVTFNINNSIPPTFDGEEEPSQGQK.V "sp|Q07021|C1QBP_HUMAN,tr|I3L3B0|I3L3B0_HUMAN,tr|I3L3Q7|I3L3Q7_HUMAN" 3 2861.3719 1.27 90934 24441 3 2861.371737 954.7979 "Complement component 1 Q subcomponent-binding protein, mitochondrial OS=Homo sapiens OX=9606 GN=C1QBP PE=1 SV=1" 4 3704.2 - 3.86E+06 - - - -0.0685 - 3.354 0.599 - 306.6 1 2 0 -0.0002 26 0 0 0 1.31E+08 1.03E+08 - - - 8.0023 1 221125_WJC_METTL3_EV_vs_WT_F06.24442.24442.3 5.25E-07 16/76 K.NNQFQALLQYADPVSAQHAK.L "sp|P26599|PTBP1_HUMAN,tr|A0A6Q8PEX4|A0A6Q8PEX4_HUMAN,tr|A0A0U1RRM4|A0A0U1RRM4_HUMAN,tr|A6NLN1|A6NLN1_HUMAN,tr|K7EKJ7|K7EKJ7_HUMAN,tr|A0A087WU68|A0A087WU68_HUMAN,tr|A0A7I2V4H6|A0A7I2V4H6_HUMAN,tr|A0A7I2V621|A0A7I2V621_HUMAN,tr|K7EK45|K7EK45_HUMAN" 9 2242.1131 1.16 90935 24442 3 2242.114066 748.3783 Polypyrimidine tract-binding protein 1 OS=Homo sapiens OX=9606 GN=PTBP1 PE=1 SV=1 6.74 3704.2 - 2.48E+06 - - - 0.4398 - 3.82 0.581 - 252.4 1 2 0 0.001 20 0 0 0 2.05E+08 1.77E+08 - - - 8.2688 0.9999 221125_WJC_METTL3_EV_vs_WT_F06.24443.24443.4 6.48E-13 34/168 R.EHPWEVMPDLYFYRDPEEIEKEEQAAAEK.A "sp|P08865|RSSA_HUMAN,tr|C9J9K3|C9J9K3_HUMAN,tr|A0A0C4DG17|A0A0C4DG17_HUMAN" 3 3577.6348 0.69 90936 24443 4 3577.635549 895.416 40S ribosomal protein SA OS=Homo sapiens OX=9606 GN=RPSA PE=1 SV=4 4.22 3704.4 - 4.75E+06 - - - 0.2189 - 5.384 0.578 - 523.2 1 2 2 0.0008 29 0 0 0 9.32E+07 1.35E+08 - - - 4.7755 1 221125_WJC_METTL3_EV_vs_WT_F06.24444.24444.3 3.52E-14 25/104 R.SSGTASSVAFTPLQGLEIVNPQAAEKK.V "sp|Q8WWY3|PRP31_HUMAN,tr|E7EVX8|E7EVX8_HUMAN" 2 2729.4236 3.04 90937 24444 3 2729.417547 910.8151 U4\U6 small nuclear ribonucleoprotein Prp31 OS=Homo sapiens OX=9606 GN=PRPF31 PE=1 SV=2 5.86 3704.5 - 1.39E+06 - - - -2.2085 - 4.764 0.66 - 626.2 1 2 0 -0.006 27 0 0 0 2.34E+08 7.68E+07 - - - 9.4882 1 221125_WJC_METTL3_EV_vs_WT_F06.24445.24445.3 2.34E-11 16/136 F.GSK[136.11]PAPGTLGTGLGAGFGTALGAGQASLFGNNQPK[136.11].L "sp|P52948|NUP98_HUMAN,tr|A0A3B3ITD8|A0A3B3ITD8_HUMAN,tr|H0YEN4|H0YEN4_HUMAN" 3 3214.6706 2.57 90938 24445 3 3214.667674 1072.5641 Nuclear pore complex protein Nup98-Nup96 OS=Homo sapiens OX=9606 GN=NUP98 PE=1 SV=4 10 3704.6 - 1.39E+06 - - - -0.9024 - 3.78 0.624 - 195.8 1 1 0 -0.0029 35 0 0 0 5.60E+07 2.18E+07 - - - 8.5554 0.8822 221125_WJC_METTL3_EV_vs_WT_F06.24449.24449.3 0.00448 Dec-88 K.QQIATEKQDLEAEVSQLTGEVAK.L "sp|O60610|DIAP1_HUMAN,tr|A0A2R8Y5N1|A0A2R8Y5N1_HUMAN,tr|A0A140T8Z0|A0A140T8Z0_HUMAN,tr|A0A0G2JH68|A0A0G2JH68_HUMAN,tr|H9KV28|H9KV28_HUMAN" 5 2514.2813 1.3 90939 24449 3 2514.288791 839.1011 Protein diaphanous homolog 1 OS=Homo sapiens OX=9606 GN=DIAPH1 PE=1 SV=2 4.25 3705.1 - 925135 - - - 2.9686 - 2.262 0.136 - 99.1 1 2 1 0.0075 23 0 0 0 1.21E+07 9.31E+06 - - - 1.9691 0.9999 221125_WJC_METTL3_EV_vs_WT_F06.24451.24451.4 2.32E-09 19/108 R.GMQDLVEDFKNKYEDEINK.R sp|P02538|K2C6A_HUMAN 1 2314.0787 113.99 90940 24451 4 2314.077217 579.527 "Keratin, type II cytoskeletal 6A OS=Homo sapiens OX=9606 GN=KRT6A PE=1 SV=3" 4.3 3705.4 - 940386 - - - -0.653 - 3.673 0.524 - 307.4 1 2 2 -0.0015 19 0 0 0 2.16E+07 1.90E+05 - - - 4.2266 1 221125_WJC_METTL3_EV_vs_WT_F06.24454.24454.3 1.20E-12 25/104 R.SSGTASSVAFTPLQGLEIVNPQAAEK[136.11]K[136.11].V "sp|Q8WWY3|PRP31_HUMAN,tr|E7EVX8|E7EVX8_HUMAN" 2 2745.452 3.02 90942 24454 3 2745.458057 916.1579 U4\U6 small nuclear ribonucleoprotein Prp31 OS=Homo sapiens OX=9606 GN=PRPF31 PE=1 SV=2 5.86 3705.8 - 1.15E+06 - - - 2.2153 - 3.833 0.675 - 534.2 1 2 0 0.0061 27 0 0 0 2.32E+08 7.68E+07 - - - 9.1551 0.9998 221125_WJC_METTL3_EV_vs_WT_F06.24455.24455.4 1.47E-08 29/168 R.EHPWEVMPDLYFYR[166.11]DPEEIEK[136.11]EEQAAAEK[136.11].A "sp|P08865|RSSA_HUMAN,tr|C9J9K3|C9J9K3_HUMAN,tr|A0A0C4DG17|A0A0C4DG17_HUMAN" 3 3603.6714 0.69 90943 24455 4 3603.662153 901.9251 40S ribosomal protein SA OS=Homo sapiens OX=9606 GN=RPSA PE=1 SV=4 4.22 3705.9 - 6.93E+06 - - - -2.576 - 4.341 0.551 - 275 1 2 2 -0.0093 29 0 0 0 9.32E+07 1.35E+08 - - - 4.4718 1 221125_WJC_METTL3_EV_vs_WT_F06.24459.24459.3 0.00092 22/76 K.HAASDVDLEIESLLNQQSTK[136.11].E "sp|Q86U44|MTA70_HUMAN,tr|F5H6D8|F5H6D8_HUMAN,tr|H0YFV6|H0YFV6_HUMAN,tr|B4DTN4|B4DTN4_HUMAN" 4 2205.1005 0.06 90945 24459 3 2206.08907 736.0408 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 4.31 3706.4 - 6.12E+06 - - - 448.3306 - 4.215 0.614 - 566.8 1 2 0 0.9886 20 0 0 0 8.35E+06 1.40E+08 - - - 8.6018 1 221125_WJC_METTL3_EV_vs_WT_F06.24460.24460.4 1.15E-08 24/90 R.HYLDFINHYANLFHEK[136.11].R "sp|Q14204|DYHC1_HUMAN,tr|A0A7P0T8N2|A0A7P0T8N2_HUMAN,tr|A0A7P0T9C4|A0A7P0T9C4_HUMAN,tr|A0A7P0TBJ7|A0A7P0TBJ7_HUMAN,tr|A0A7P0T9K2|A0A7P0T9K2_HUMAN,tr|A0A2R8Y706|A0A2R8Y706_HUMAN,tr|A0A7P0T916|A0A7P0T916_HUMAN,tr|A0A7P0TB75|A0A7P0TB75_HUMAN,tr|A0A7P0T8W5|A0A7P0T8W5_HUMAN,tr|A0A7P0TAF3|A0A7P0TAF3_HUMAN,tr|A0A7P0T9F1|A0A7P0T9F1_HUMAN,tr|A0A7P0TAW9|A0A7P0TAW9_HUMAN,tr|A0A7P0TA13|A0A7P0TA13_HUMAN,tr|A0A7P0T7V5|A0A7P0T7V5_HUMAN,tr|A0A7P0T9R4|A0A7P0T9R4_HUMAN,tr|A0A2R8Y5T0|A0A2R8Y5T0_HUMAN,tr|A0A2R8YFZ7|A0A2R8YFZ7_HUMAN,tr|A0A7P0T825|A0A7P0T825_HUMAN,tr|A0A2R8Y6H2|A0A2R8Y6H2_HUMAN,tr|A0A7P0TAM4|A0A7P0TAM4_HUMAN" 20 2068.0046 0.82 90946 24460 4 2068.003542 518.0084 Cytoplasmic dynein 1 heavy chain 1 OS=Homo sapiens OX=9606 GN=DYNC1H1 PE=1 SV=5 6.26 3706.5 - 1.08E+06 - - - -0.5334 - 3.905 0.562 - 591.2 1 2 0 -0.0011 16 0 0 0 2.75E+07 3.34E+07 - - - 4.5972 0.9993 221125_WJC_METTL3_EV_vs_WT_F06.24474.24474.4 0.000812 21/132 R.TIEDAIAVLSVAEEAADR[166.11]HPER[166.11]R[166.11].M sp|Q96CT7|CC124_HUMAN 1 2577.3289 0.51 90952 24474 4 2577.320271 645.3395 Coiled-coil domain-containing protein 124 OS=Homo sapiens OX=9606 GN=CCDC124 PE=1 SV=1 4.64 3708.2 - 1.43E+06 - - - -3.3628 - 3.518 0.471 - 154 1 2 1 -0.0087 23 0 0 0 2.16E+07 4.20E+07 - - - 3.7307 0.995 221125_WJC_METTL3_EV_vs_WT_F06.24475.24475.3 0.108 Oct-60 R.HYLDFINHYANLFHEK.R "sp|Q14204|DYHC1_HUMAN,tr|A0A7P0T8N2|A0A7P0T8N2_HUMAN,tr|A0A7P0T9C4|A0A7P0T9C4_HUMAN,tr|A0A7P0TBJ7|A0A7P0TBJ7_HUMAN,tr|A0A7P0T9K2|A0A7P0T9K2_HUMAN,tr|A0A2R8Y706|A0A2R8Y706_HUMAN,tr|A0A7P0T916|A0A7P0T916_HUMAN,tr|A0A7P0TB75|A0A7P0TB75_HUMAN,tr|A0A7P0T8W5|A0A7P0T8W5_HUMAN,tr|A0A7P0TAF3|A0A7P0TAF3_HUMAN,tr|A0A7P0T9F1|A0A7P0T9F1_HUMAN,tr|A0A7P0TAW9|A0A7P0TAW9_HUMAN,tr|A0A7P0TA13|A0A7P0TA13_HUMAN,tr|A0A7P0T7V5|A0A7P0T7V5_HUMAN,tr|A0A7P0T9R4|A0A7P0T9R4_HUMAN,tr|A0A2R8Y5T0|A0A2R8Y5T0_HUMAN,tr|A0A2R8YFZ7|A0A2R8YFZ7_HUMAN,tr|A0A7P0T825|A0A7P0T825_HUMAN,tr|A0A2R8Y6H2|A0A2R8Y6H2_HUMAN,tr|A0A7P0TAM4|A0A7P0TAM4_HUMAN" 20 2059.9904 0.69 90953 24475 3 2059.989321 687.6708 Cytoplasmic dynein 1 heavy chain 1 OS=Homo sapiens OX=9606 GN=DYNC1H1 PE=1 SV=5 6.26 3708.3 - 332770 - - - -0.5456 - 1.624 0.22 - 82 1 2 0 -0.0011 16 0 0 0 3.39E+06 4.89E+06 - - - 2.2366 0.8589 221125_WJC_METTL3_EV_vs_WT_F06.24487.24487.3 0.24 Jul-60 R.QSIDALK[136.11]DWFR[166.11]DEMQK[136.11].S "sp|O60841|IF2P_HUMAN,tr|A0A087WUT6|A0A087WUT6_HUMAN" 2 2035.0043 0.19 90960 24487 3 2034.99709 679.3421 Eukaryotic translation initiation factor 5B OS=Homo sapiens OX=9606 GN=EIF5B PE=1 SV=4 4.68 3709.8 - 461725 - - - -3.5582 - 1.892 0.172 - 58.9 1 2 2 -0.0072 16 0 0 0 2.37E+06 1.23E+07 - - - 2.0917 0.9998 221125_WJC_METTL3_EV_vs_WT_F06.24492.24492.4 0.00031 21/114 K.HTTPFSVSDILSPIEETYKK.F sp|Q9H2Z4|NKX24_HUMAN 1 2291.1685 1.22 90963 24492 4 2291.175538 573.7994 Homeobox protein Nkx-2.4 OS=Homo sapiens OX=9606 GN=NKX2-4 PE=1 SV=3 5.45 3710.5 - 815272 - - - 3.0591 - 3.337 0.436 - 372.2 1 2 0 0.007 20 0 0 0 3.81E+07 3.14E+07 - - - 3.4219 1 221125_WJC_METTL3_EV_vs_WT_F06.24496.24496.3 4.80E-07 18/76 K.HTTPFSVSDILSPIEETYKK.F sp|Q9H2Z4|NKX24_HUMAN 1 2291.1685 8.94 90965 24496 3 2291.165987 764.7301 Homeobox protein Nkx-2.4 OS=Homo sapiens OX=9606 GN=NKX2-4 PE=1 SV=3 5.45 3711.1 - 753152 - - - -1.1095 - 3.901 0.387 - 415.3 1 2 0 -0.0025 20 0 0 0 2.56E+07 2.87E+06 - - - 6.1563 1 221125_WJC_METTL3_EV_vs_WT_F06.24501.24501.4 3.33E-15 26/156 R.ATEDGEEDEEMIESIENLEDLK[136.11]GHSVR[166.11].E "sp|P49736|MCM2_HUMAN,tr|H0Y8E6|H0Y8E6_HUMAN" 2 3091.3895 5.55 90968 24501 4 3091.385571 773.8546 DNA replication licensing factor MCM2 OS=Homo sapiens OX=9606 GN=MCM2 PE=1 SV=4 3.95 3711.7 - 1.07E+06 - - - -1.2561 - 4.41 0.684 - 458.5 1 2 1 -0.0039 27 0 0 0 7.17E+07 1.29E+07 - - - 5.6428 1 221125_WJC_METTL3_EV_vs_WT_F06.24504.24504.4 7.20E-07 17/180 K.LVSSSNAMENASHQASVQVESLQEQLNVVSK.Q "sp|Q15643|TRIPB_HUMAN,tr|H0YJI2|H0YJI2_HUMAN,tr|H0YJ97|H0YJ97_HUMAN" 3 3312.6256 1.8 90971 24504 4 3312.627341 829.1637 Thyroid receptor-interacting protein 11 OS=Homo sapiens OX=9606 GN=TRIP11 PE=1 SV=3 4.75 3712.1 - 1.24E+06 - - - 0.5262 - 2.891 0.513 - 77.7 1 2 0 0.0017 31 0 0 0 3.08E+08 1.71E+08 - - - 4.0133 1 221125_WJC_METTL3_EV_vs_WT_F06.24512.24512.3 2.10E-15 23/120 K.LVSSSNAMENASHQASVQVESLQEQLNVVSK[136.11].Q "sp|Q15643|TRIPB_HUMAN,tr|H0YJI2|H0YJI2_HUMAN,tr|H0YJ97|H0YJ97_HUMAN" 3 3320.6398 0.37 90976 24512 3 3320.633892 1107.8872 Thyroid receptor-interacting protein 11 OS=Homo sapiens OX=9606 GN=TRIP11 PE=1 SV=3 4.75 3713.1 - 2.24E+06 - - - -1.7786 - 4.768 0.628 - 486.8 1 2 0 -0.0059 31 0 0 0 6.39E+07 1.72E+08 - - - 9.1334 0.9989 221125_WJC_METTL3_EV_vs_WT_F06.24514.24514.4 1.20E-06 17/114 K.HAASDVDLEIESLLNQQSTK[136.11].E "sp|Q86U44|MTA70_HUMAN,tr|F5H6D8|F5H6D8_HUMAN,tr|H0YFV6|H0YFV6_HUMAN,tr|B4DTN4|B4DTN4_HUMAN" 4 2205.1005 0.01 90978 24514 4 2206.099282 552.2824 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 4.31 3713.3 - 580378 - - - 452.9617 - 3.361 0.57 - 233.5 1 2 0 0.9988 20 0 0 0 8.72E+06 1.25E+09 - - - 4.3159 1 221125_WJC_METTL3_EV_vs_WT_F06.24523.24523.3 1.07E-07 23/92 K.K[136.11]QEDSVTELTVEDSGESLEDLMAK[136.11].M "sp|Q9GZZ9|UBA5_HUMAN,tr|A0A804HJ86|A0A804HJ86_HUMAN" 2 2668.2608 0.89 90983 24523 3 2668.257994 890.4275 Ubiquitin-like modifier-activating enzyme 5 OS=Homo sapiens OX=9606 GN=UBA5 PE=1 SV=1 3.89 3714.5 - 1.75E+06 - - - -1.0471 - 4.66 0.615 - 726.9 1 2 0 -0.0028 24 0 0 0 1.50E+07 1.69E+07 - - - 8.9704 1 221125_WJC_METTL3_EV_vs_WT_F06.24535.24535.4 3.47E-09 17/180 K.LVSSSNAMENASHQASVQVESLQEQLNVVSK[136.11].Q "sp|Q15643|TRIPB_HUMAN,tr|H0YJI2|H0YJI2_HUMAN,tr|H0YJ97|H0YJ97_HUMAN" 3 3320.6398 1.8 90990 24535 4 3320.628602 831.1672 Thyroid receptor-interacting protein 11 OS=Homo sapiens OX=9606 GN=TRIP11 PE=1 SV=3 4.75 3715.9 - 9.65E+06 - - - -3.3716 - 3.527 0.628 - 155.5 1 2 0 -0.0112 31 0 0 0 3.08E+08 1.71E+08 - - - 5.0721 1 221125_WJC_METTL3_EV_vs_WT_F06.24557.24557.2 2.01E-07 19/38 K.HAASDVDLEIESLLNQQSTK.E "sp|Q86U44|MTA70_HUMAN,tr|F5H6D8|F5H6D8_HUMAN,tr|H0YFV6|H0YFV6_HUMAN,tr|B4DTN4|B4DTN4_HUMAN" 4 2197.0863 0.02 91000 24557 2 2198.081674 1099.5504 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 4.31 3718.6 - 1.21E+07 - - - 453.0628 - 4.001 0.657 - 655.1 1 2 0 0.9954 20 0 0 0 4.34E+08 1.84E+10 - - - 6.9899 1 221125_WJC_METTL3_EV_vs_WT_F06.24575.24575.4 1.06E-08 27/150 R.SFGTEDRPTDRPIPPRDEVFEYIIFR.G "sp|Q8ND56|LS14A_HUMAN,tr|I3L4Q1|I3L4Q1_HUMAN,tr|A0A140TA76|A0A140TA76_HUMAN,tr|K7EMZ9|K7EMZ9_HUMAN" 4 3151.5727 1.05 91007 24575 4 3151.563533 788.9005 Protein LSM14 homolog A OS=Homo sapiens OX=9606 GN=LSM14A PE=1 SV=3 4.59 3720.8 - 2.05E+07 - - - -2.9084 - 3.791 0.641 - 148.9 1 2 1 -0.0092 26 0 0 0 1.55E+09 1.48E+09 - - - 5.2231 0.9999 221125_WJC_METTL3_EV_vs_WT_F06.24614.24614.4 8.51E-07 15/162 R.GPLPLSSQHR[166.11]GDADQASNILASFGLSAR[166.11].D "sp|P43243|MATR3_HUMAN,tr|A8MXP9|A8MXP9_HUMAN,tr|D6R991|D6R991_HUMAN,tr|A0A0R4J2E8|A0A0R4J2E8_HUMAN,tr|D6REM6|D6REM6_HUMAN" 5 2884.4695 1.23 91016 24614 4 2884.472561 722.1246 Matrin-3 OS=Homo sapiens OX=9606 GN=MATR3 PE=1 SV=2 6.75 3726.4 - 9.77E+06 - - - 1.0758 - 3.112 0.537 - 90.3 1 2 1 0.0031 28 0 0 0 1.16E+09 9.43E+08 - - - 4.2517 0.9999 221125_WJC_METTL3_EV_vs_WT_F06.24616.24616.4 2.65E-07 22/162 R.GPLPLSSQHRGDADQASNILASFGLSAR.D "sp|P43243|MATR3_HUMAN,tr|A8MXP9|A8MXP9_HUMAN,tr|D6R991|D6R991_HUMAN,tr|A0A0R4J2E8|A0A0R4J2E8_HUMAN,tr|D6REM6|D6REM6_HUMAN" 5 2864.4529 1.23 91017 24616 4 2864.458018 717.1205 Matrin-3 OS=Homo sapiens OX=9606 GN=MATR3 PE=1 SV=2 6.75 3726.6 - 7.76E+06 - - - 1.7804 - 3.459 0.605 - 247.6 1 2 1 0.0051 28 0 0 0 1.16E+09 9.43E+08 - - - 4.8758 1 221125_WJC_METTL3_EV_vs_WT_F06.24620.24620.4 2.35E-10 28/174 R.TNLDESDVQPVKEQLAQAMFDHIPVGVGSK.G sp|Q9Y3I0|RTCB_HUMAN 1 3251.6132 1.55 91019 24620 4 3251.61013 813.9106 RNA-splicing ligase RtcB homolog OS=Homo sapiens OX=9606 GN=RTCB PE=1 SV=1 4.43 3727.1 - 1.32E+07 - - - -0.9574 - 3.741 0.628 - 281 1 2 1 -0.0031 30 0 0 0 8.37E+08 5.40E+08 - - - 5.095 1 221125_WJC_METTL3_EV_vs_WT_F06.24627.24627.4 1.13E-13 31/174 R.TNLDESDVQPVK[136.11]EQLAQAMFDHIPVGVGSK[136.11].G sp|Q9Y3I0|RTCB_HUMAN 1 3267.6416 1.56 91021 24627 4 3267.63332 817.9177 RNA-splicing ligase RtcB homolog OS=Homo sapiens OX=9606 GN=RTCB PE=1 SV=1 4.43 3728.1 - 1.67E+07 - - - -2.5471 - 4.328 0.684 - 364.1 1 2 1 -0.0083 30 0 0 0 8.35E+08 5.34E+08 - - - 5.6256 1 221125_WJC_METTL3_EV_vs_WT_F06.24634.24634.3 5.37E-15 31/108 R.GPLPLSSQHRGDADQASNILASFGLSAR.D "sp|P43243|MATR3_HUMAN,tr|A8MXP9|A8MXP9_HUMAN,tr|D6R991|D6R991_HUMAN,tr|A0A0R4J2E8|A0A0R4J2E8_HUMAN,tr|D6REM6|D6REM6_HUMAN" 5 2864.4529 1.35 91025 24634 3 2864.444523 955.8249 Matrin-3 OS=Homo sapiens OX=9606 GN=MATR3 PE=1 SV=2 6.75 3729 - 6.03E+06 - - - -2.9308 - 5.068 0.708 - 740 1 2 1 -0.0084 28 0 0 0 1.85E+08 1.37E+08 - - - 10.165 1 221125_WJC_METTL3_EV_vs_WT_F06.24636.24636.3 1.48E-13 28/108 R.GPLPLSSQHR[166.11]GDADQASNILASFGLSAR[166.11].D "sp|P43243|MATR3_HUMAN,tr|A8MXP9|A8MXP9_HUMAN,tr|D6R991|D6R991_HUMAN,tr|A0A0R4J2E8|A0A0R4J2E8_HUMAN,tr|D6REM6|D6REM6_HUMAN" 5 2884.4695 1.35 91027 24636 3 2884.465071 962.4971 Matrin-3 OS=Homo sapiens OX=9606 GN=MATR3 PE=1 SV=2 6.75 3729.2 - 4.65E+06 - - - -1.5209 - 4.761 0.686 - 526.4 1 2 1 -0.0044 28 0 0 0 1.85E+08 1.37E+08 - - - 9.7771 1 221125_WJC_METTL3_EV_vs_WT_F06.24637.24637.3 1.64E-14 33/100 R.QLLAQQLGAESADSIGAVLNSK[136.11]DEQR[166.11].E "sp|Q9HCE5|MET14_HUMAN,tr|A0A0D9SFW0|A0A0D9SFW0_HUMAN,tr|A0A0D9SF88|A0A0D9SF88_HUMAN" 3 2758.4216 0.01 91028 24637 3 2758.415242 920.4812 N6-adenosine-methyltransferase non-catalytic subunit OS=Homo sapiens OX=9606 GN=METTL14 PE=1 SV=2 4.32 3729.3 - 2.49E+06 - - - -2.3126 - 5.716 0.648 - 1023.4 1 2 1 -0.0064 26 0 0 0 3.65E+05 5.74E+07 - - - 9.7734 1 221125_WJC_METTL3_EV_vs_WT_F06.24642.24642.4 1.84E-09 31/132 R.SNHEEEVADLLAQIQASHITVER.K "sp|P07197|NFM_HUMAN,tr|E7ESP9|E7ESP9_HUMAN,tr|E7EMV2|E7EMV2_HUMAN" 3 2588.2831 7.05 91031 24642 4 2588.281276 648.078 Neurofilament medium polypeptide OS=Homo sapiens OX=9606 GN=NEFM PE=1 SV=3 4.56 3729.9 - 6.63E+06 - - - -0.6885 - 5.411 0.715 - 1023.1 1 2 0 -0.0018 23 0 0 0 5.33E+08 7.56E+07 - - - 5.9959 1 221125_WJC_METTL3_EV_vs_WT_F06.24644.24644.3 4.95E-17 40/88 R.SNHEEEVADLLAQIQASHITVER.K "sp|P07197|NFM_HUMAN,tr|E7ESP9|E7ESP9_HUMAN,tr|E7EMV2|E7EMV2_HUMAN" 3 2588.2831 4.23 91033 24644 3 2588.281842 863.7683 Neurofilament medium polypeptide OS=Homo sapiens OX=9606 GN=NEFM PE=1 SV=3 4.56 3730.1 - 3.67E+06 - - - -0.4698 - 6.578 0.732 - 2593.4 1 2 0 -0.0012 23 0 0 0 1.34E+08 3.17E+07 - - - 11.1199 1 221125_WJC_METTL3_EV_vs_WT_F06.24652.24652.4 1.13E-19 30/132 R.SNHEEEVADLLAQIQASHITVER[166.11].K "sp|P07197|NFM_HUMAN,tr|E7ESP9|E7ESP9_HUMAN,tr|E7EMV2|E7EMV2_HUMAN" 3 2598.2913 6.91 91037 24652 4 2598.28731 650.5801 Neurofilament medium polypeptide OS=Homo sapiens OX=9606 GN=NEFM PE=1 SV=3 4.56 3731.1 - 3.57E+06 - - - -1.5464 - 5.709 0.716 - 998.9 1 2 0 -0.004 23 0 0 0 5.20E+08 7.53E+07 - - - 6.0214 1 221125_WJC_METTL3_EV_vs_WT_F06.24654.24654.3 6.31E-08 15/68 K.YVHYEIDAC[160.03]MDSEAPGSK[136.11].D "sp|Q86U44|MTA70_HUMAN,tr|H0YFV6|H0YFV6_HUMAN" 2 2078.8805 0.001 91038 24654 3 2078.878391 693.9674 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 4.31 3731.3 - 1.47E+06 - - - -1.0106 - 3.128 0.607 - 230.4 1 2 0 -0.0021 18 0 0 0 0.00E+00 4.19E+07 - - - 8.1466 0.9924 221125_WJC_METTL3_EV_vs_WT_F06.24656.24656.4 3.04E-05 16/222 R.AFGPSETNESPAVVLEPPVVSMEVSEPHILETLK[136.11]PATK[136.11].T sp|P18583|SON_HUMAN 1 4045.0941 -1 91039 24656 4 4045.060287 1012.2808 Protein SON OS=Homo sapiens OX=9606 GN=SON PE=1 SV=4 4.47 3731.5 - 3.70E+06 - - - -8.3469 - 2.014 0.452 - 61.6 1 2 0 -0.0338 38 0 0 0 0.00E+00 0.00E+00 - - - 3.355 0.9999 221125_WJC_METTL3_EV_vs_WT_F06.24666.24666.4 0.000192 15/126 R.ESEEENLNK[136.11]SEISQVFEIALK[136.11]R[166.11].N "sp|O95793|STAU1_HUMAN,tr|Q5JW30|Q5JW30_HUMAN,tr|Q5JW28|Q5JW28_HUMAN" 3 2617.3445 2.53 91045 24666 4 2617.341223 655.3434 Double-stranded RNA-binding protein Staufen homolog 1 OS=Homo sapiens OX=9606 GN=STAU1 PE=1 SV=2 4.48 3732.6 - 4.00E+06 - - - -1.2696 - 3.108 0.565 - 128.8 1 2 1 -0.0033 22 0 0 0 3.78E+08 1.49E+08 - - - 4.5139 1 221125_WJC_METTL3_EV_vs_WT_F06.24668.24668.3 2.01E-13 31/88 R.SNHEEEVADLLAQIQASHITVER[166.11].K "sp|P07197|NFM_HUMAN,tr|E7ESP9|E7ESP9_HUMAN,tr|E7EMV2|E7EMV2_HUMAN" 3 2598.2913 4.22 91047 24668 3 2598.289674 867.1044 Neurofilament medium polypeptide OS=Homo sapiens OX=9606 GN=NEFM PE=1 SV=3 4.56 3732.8 - 2.12E+06 - - - -0.6366 - 6.055 0.705 - 1174.2 1 2 0 -0.0017 23 0 0 0 1.34E+08 3.17E+07 - - - 10.6244 1 221125_WJC_METTL3_EV_vs_WT_F06.24672.24672.2 1.01E-13 23/38 K.HAASDVDLEIESLLNQQSTK[136.11].E "sp|Q86U44|MTA70_HUMAN,tr|F5H6D8|F5H6D8_HUMAN,tr|H0YFV6|H0YFV6_HUMAN,tr|B4DTN4|B4DTN4_HUMAN" 4 2205.1005 0.04 91049 24672 2 2206.097324 1103.5575 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 4.31 3733.2 - 5.43E+06 - - - 452.0737 - 4.197 0.647 - 1171.3 1 2 0 0.9969 20 0 0 0 3.48E+06 8.78E+07 - - - 7.0332 0.9999 221125_WJC_METTL3_EV_vs_WT_F06.24685.24685.4 1.20E-10 24/180 K.GIEILTDMSR[166.11]PVELSDR[166.11]ETLLNSATTSLNSK[136.11].V sp|P50991|TCPD_HUMAN 1 3417.7656 0.2 91057 24685 4 3417.766092 855.4487 T-complex protein 1 subunit delta OS=Homo sapiens OX=9606 GN=CCT4 PE=1 SV=4 4.51 3734.7 - 2.05E+06 - - - 0.1571 - 4.458 0.521 - 324.9 1 2 1 0.0005 31 0 0 0 3.07E+07 1.56E+08 - - - 4.2149 0.9999 221125_WJC_METTL3_EV_vs_WT_F06.24688.24688.4 0.000232 14/108 R.GLLQDDAHPTLVTYADHSK[136.11].L "sp|Q86U44|MTA70_HUMAN,tr|F5H6D8|F5H6D8_HUMAN,tr|H0YFV6|H0YFV6_HUMAN,tr|B4DTN4|B4DTN4_HUMAN" 4 2088.0367 0.001 91058 24688 4 2088.036487 523.0165 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 5.13 3735.1 - 518323 - - - -0.1178 - 2.894 0.442 - 175.9 1 2 0 -0.0002 19 0 0 0 0.00E+00 2.61E+07 - - - 3.4326 0.992 221125_WJC_METTL3_EV_vs_WT_F06.24691.24691.4 0.000753 19/102 R.K[136.11]HAASDVDLEIESLLNQQ.S "sp|Q86U44|MTA70_HUMAN,tr|F5H6D8|F5H6D8_HUMAN,tr|H0YFV6|H0YFV6_HUMAN,tr|B4DTN4|B4DTN4_HUMAN" 4 2017.0207 0.04 91061 24691 4 2017.017513 505.2625 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 4.31 3735.4 - 680666 - - - -1.6043 - 3.289 0.447 - 384.7 1 1 0 -0.0032 18 0 0 0 8.85E+05 2.36E+07 - - - 3.5236 0.9999 221125_WJC_METTL3_EV_vs_WT_F06.24694.24694.4 8.29E-11 28/162 R.TVSLGAGAKDELHIVEAEAMNYEGSPIK.V "sp|P06748|NPM_HUMAN,tr|A0A7I2V4G8|A0A7I2V4G8_HUMAN,tr|A0A7I2YQC0|A0A7I2YQC0_HUMAN,tr|A0A7I2V433|A0A7I2V433_HUMAN,tr|A0A7I2V579|A0A7I2V579_HUMAN,tr|A0A7I2V2X9|A0A7I2V2X9_HUMAN,tr|A0A7I2V3G5|A0A7I2V3G5_HUMAN,tr|A0A7I2V5S2|A0A7I2V5S2_HUMAN,tr|A0A7I2V3U2|A0A7I2V3U2_HUMAN" 9 2928.4539 1.46 91062 24694 4 2928.451477 733.1207 Nucleophosmin OS=Homo sapiens OX=9606 GN=NPM1 PE=1 SV=2 4.57 3735.8 - 5.15E+06 - - - -0.8236 - 5.011 0.568 - 650.2 1 2 1 -0.0024 28 0 0 0 1.24E+08 8.48E+07 - - - 4.6696 1 221125_WJC_METTL3_EV_vs_WT_F06.24699.24699.3 1.57E-11 29/88 R.RDNYVPEVSALDQEIIEVDPDTK.E "sp|P08708|RS17_HUMAN,tr|H3BNC9|H3BNC9_HUMAN,tr|H0YN88|H0YN88_HUMAN,tr|A0A075B716|A0A075B716_HUMAN" 4 2644.2868 0.72 91065 24699 3 2644.281614 882.4362 40S ribosomal protein S17 OS=Homo sapiens OX=9606 GN=RPS17 PE=1 SV=2 3.9 3736.4 - 2.30E+06 - - - -1.9635 - 4.346 0.665 - 763.2 1 2 0 -0.0052 23 0 0 0 1.14E+08 1.58E+08 - - - 9.3994 1 221125_WJC_METTL3_EV_vs_WT_F06.24706.24706.3 4.69E-12 21/108 R.TVSLGAGAK[136.11]DELHIVEAEAMNYEGSPIK[136.11].V "sp|P06748|NPM_HUMAN,tr|A0A7I2V4G8|A0A7I2V4G8_HUMAN,tr|A0A7I2YQC0|A0A7I2YQC0_HUMAN,tr|A0A7I2V433|A0A7I2V433_HUMAN,tr|A0A7I2V579|A0A7I2V579_HUMAN,tr|A0A7I2V2X9|A0A7I2V2X9_HUMAN,tr|A0A7I2V3G5|A0A7I2V3G5_HUMAN,tr|A0A7I2V5S2|A0A7I2V5S2_HUMAN,tr|A0A7I2V3U2|A0A7I2V3U2_HUMAN" 9 2944.4823 0.72 91068 24706 3 2944.470625 982.5014 Nucleophosmin OS=Homo sapiens OX=9606 GN=NPM1 PE=1 SV=2 4.57 3737.2 - 1.00E+06 - - - -3.9613 - 4.67 0.63 - 386.7 1 2 1 -0.0117 28 0 0 0 1.76E+07 2.43E+07 - - - 9.1063 1 221125_WJC_METTL3_EV_vs_WT_F06.24711.24711.3 1.69E-05 Dec-72 K.ILTATVDNANVLLQIDNAR.L sp|P02533|K1C14_HUMAN 1 2053.1168 92.13 91073 24711 3 2053.116968 685.3795 "Keratin, type I cytoskeletal 14 OS=Homo sapiens OX=9606 GN=KRT14 PE=1 SV=4" 4.21 3737.9 - 694094 - - - 0.0974 - 2.662 0.459 - 193.5 1 2 0 0.0002 19 0 0 0 2.26E+07 2.46E+05 - - - 6.0627 1 221125_WJC_METTL3_EV_vs_WT_F06.24719.24719.3 4.57E-09 16/64 K.VTLENFYSNLIAQHEER.E sp|Q15208|STK38_HUMAN 1 2062.012 22.66 91075 24719 3 2062.006668 688.3446 Serine\threonine-protein kinase 38 OS=Homo sapiens OX=9606 GN=STK38 PE=1 SV=1 4.75 3738.8 - 845958 - - - -2.5708 - 3.35 0.543 - 325.6 1 2 0 -0.0053 17 0 0 0 3.49E+07 1.54E+06 - - - 7.6466 0.9992 221125_WJC_METTL3_EV_vs_WT_F06.24726.24726.2 0.0266 18-Oct K.ILLAELEQLK[136.11].G "sp|P08670|VIME_HUMAN,tr|B0YJC4|B0YJC4_HUMAN,tr|A0A1B0GTT5|A0A1B0GTT5_HUMAN" 3 1176.7209 1.86 91079 24726 2 1176.720706 589.3677 Vimentin OS=Homo sapiens OX=9606 GN=VIM PE=1 SV=4 4.53 3739.8 - 346120 - - - -0.1861 - 1.744 0.273 - 184.6 1 2 0 -0.0002 10 0 0 0 1.14E+07 6.12E+06 - - - 2.6098 1 221125_WJC_METTL3_EV_vs_WT_F06.24731.24731.4 1.77E-07 25/162 R.ESGGHHYVNMTLPVDAVISVAPEETWGK.V "sp|Q9NUQ7|UFSP2_HUMAN,tr|D6RGX2|D6RGX2_HUMAN,tr|H0YA18|H0YA18_HUMAN" 3 3022.4495 1.91 91082 24731 4 3022.450742 756.6196 Ufm1-specific protease 2 OS=Homo sapiens OX=9606 GN=UFSP2 PE=1 SV=3 4.8 3740.4 - 1.69E+06 - - - 0.4202 - 3.677 0.511 - 342.8 1 2 0 0.0013 28 0 0 0 6.68E+07 3.50E+07 - - - 4.0777 1 221125_WJC_METTL3_EV_vs_WT_F06.24734.24734.2 1.56E-09 14/32 R.STGEAFVQFASQEIAEK[136.11].A "sp|P55795|HNRH2_HUMAN,sp|P31943|HNRH1_HUMAN,tr|E5RGH4|E5RGH4_HUMAN,tr|H0YB39|H0YB39_HUMAN,tr|E5RGV0|E5RGV0_HUMAN,tr|E9PCY7|E9PCY7_HUMAN,tr|D6RIU0|D6RIU0_HUMAN,tr|D6RBM0|D6RBM0_HUMAN,tr|G8JLB6|G8JLB6_HUMAN,tr|E7EN40|E7EN40_HUMAN" 10 1848.8985 0.61 91085 24734 2 1848.898845 925.4565 Heterogeneous nuclear ribonucleoprotein H2 OS=Homo sapiens OX=9606 GN=HNRNPH2 PE=1 SV=1 4.25 3740.8 - 491214 - - - 0.1817 - 3.009 0.655 - 671.1 1 2 0 0.0003 17 0 0 0 5.97E+06 9.73E+06 - - - 6.5871 0.9996 221125_WJC_METTL3_EV_vs_WT_F06.24738.24738.2 0.016 18-Sep K.ILLAELEQLK.G "sp|P08670|VIME_HUMAN,tr|B0YJC4|B0YJC4_HUMAN,tr|A0A1B0GTT5|A0A1B0GTT5_HUMAN" 3 1168.7067 1.86 91087 24738 2 1168.708309 585.3606 Vimentin OS=Homo sapiens OX=9606 GN=VIM PE=1 SV=4 4.53 3741.3 - 855894 - - - 1.3553 - 1.903 0.392 - 155.4 1 2 0 0.0016 10 0 0 0 1.14E+07 6.12E+06 - - - 3.7318 1 221125_WJC_METTL3_EV_vs_WT_F06.24741.24741.4 3.27E-09 18/132 K.K[136.11]QEIEK[136.11]PVAVSELFTTLPIVQGK[136.11].S "sp|P78346|RPP30_HUMAN,tr|Q5VU11|Q5VU11_HUMAN" 2 2577.4844 0.97 91090 24741 4 2577.486678 645.3784 Ribonuclease P protein subunit p30 OS=Homo sapiens OX=9606 GN=RPP30 PE=1 SV=1 6.23 3741.6 - 695406 - - - 0.8873 - 3.905 0.642 - 149.9 1 2 0 0.0023 23 0 0 0 7.12E+07 7.38E+07 - - - 5.2547 0.9999 221125_WJC_METTL3_EV_vs_WT_F06.24766.24766.4 1.47E-05 14/168 K.MK[136.11]EIAEAYLGK[136.11]TVTNAVVTVPAYFNDSQR[166.11].Q "sp|P11142|HSP7C_HUMAN,tr|E9PQQ4|E9PQQ4_HUMAN,tr|E9PN89|E9PN89_HUMAN,tr|E9PLF4|E9PLF4_HUMAN,tr|E9PI65|E9PI65_HUMAN,tr|E9PK54|E9PK54_HUMAN,tr|E9PQK7|E9PQK7_HUMAN" 7 3240.6699 0.06 91106 24766 4 3240.666875 811.1748 Heat shock cognate 71 kDa protein OS=Homo sapiens OX=9606 GN=HSPA8 PE=1 SV=1 5.94 3744.8 - 1.04E+06 - - - -0.9396 - 3.057 0.509 - 57.2 1 2 2 -0.003 29 0 0 0 1.85E+06 3.08E+07 - - - 3.9999 0.9996 221125_WJC_METTL3_EV_vs_WT_F06.24768.24768.4 2.53E-05 19/126 R.ESEEENLNKSEISQVFEIALKR.N "sp|O95793|STAU1_HUMAN,tr|Q5JW30|Q5JW30_HUMAN,tr|Q5JW28|Q5JW28_HUMAN" 3 2591.3079 2.54 91108 24768 4 2591.316513 648.8342 Double-stranded RNA-binding protein Staufen homolog 1 OS=Homo sapiens OX=9606 GN=STAU1 PE=1 SV=2 4.48 3745.1 - 766063 - - - 3.3331 - 3.135 0.517 - 229.3 1 2 1 0.0086 22 0 0 0 3.78E+08 1.49E+08 - - - 4.0974 0.9974 221125_WJC_METTL3_EV_vs_WT_F06.24773.24773.2 0.0982 16-Jul K.DAEEWFFTK.T sp|P02533|K1C14_HUMAN 1 1171.5186 24.94 91111 24773 2 1171.521245 586.7666 "Keratin, type I cytoskeletal 14 OS=Homo sapiens OX=9606 GN=KRT14 PE=1 SV=4" 4.14 3745.7 - 465705 - - - 2.2663 - 1.852 0.216 - 158.2 1 2 0 0.0027 9 0 0 0 1.18E+07 4.72E+05 - - - 2.4184 1 221125_WJC_METTL3_EV_vs_WT_F06.24788.24788.4 3.60E-07 28/126 K.TSQLLETLNQLSTHTHVVDITR.T "sp|Q14203|DCTN1_HUMAN,tr|A0A804CDA6|A0A804CDA6_HUMAN,tr|E7EX90|E7EX90_HUMAN,tr|A0A7P0Z4C3|A0A7P0Z4C3_HUMAN,tr|E7EWF7|E7EWF7_HUMAN" 5 2505.3187 1.81 91119 24788 4 2505.32034 627.337 Dynactin subunit 1 OS=Homo sapiens OX=9606 GN=DCTN1 PE=1 SV=3 5.92 3747.6 - 2.04E+06 - - - 0.6482 - 4.83 0.538 - 984.5 1 2 0 0.0016 22 0 0 0 2.04E+08 1.12E+08 - - - 4.4236 1 221125_WJC_METTL3_EV_vs_WT_F06.24807.24807.3 5.72E-14 24/76 K.NFGQELAQVQHSIGQLC[160.03]NTK.D "sp|Q15643|TRIPB_HUMAN,tr|H0YJ97|H0YJ97_HUMAN" 2 2271.1066 1.15 91126 24807 3 2271.100492 758.0428 Thyroid receptor-interacting protein 11 OS=Homo sapiens OX=9606 GN=TRIP11 PE=1 SV=3 6.74 3750.2 - 5.03E+06 - - - -2.696 - 4.519 0.577 - 471.4 1 2 0 -0.0061 20 0 0 0 1.90E+08 1.66E+08 - - - 8.6304 1 221125_WJC_METTL3_EV_vs_WT_F06.24812.24812.4 4.79E-12 31/126 K.TSQLLETLNQLSTHTHVVDITR[166.11].T "sp|Q14203|DCTN1_HUMAN,tr|A0A804CDA6|A0A804CDA6_HUMAN,tr|E7EX90|E7EX90_HUMAN,tr|A0A7P0Z4C3|A0A7P0Z4C3_HUMAN,tr|E7EWF7|E7EWF7_HUMAN" 5 2515.327 1.8 91127 24812 4 2515.322556 629.839 Dynactin subunit 1 OS=Homo sapiens OX=9606 GN=DCTN1 PE=1 SV=3 5.92 3750.9 - 6.15E+06 - - - -1.7612 - 5.398 0.605 - 1167.5 1 2 0 -0.0044 22 0 0 0 2.03E+08 1.12E+08 - - - 5.0424 1 221125_WJC_METTL3_EV_vs_WT_F06.24814.24814.3 1.14E-10 20/76 K.NFGQELAQVQHSIGQLC[160.03]NTK[136.11].D "sp|Q15643|TRIPB_HUMAN,tr|H0YJ97|H0YJ97_HUMAN" 2 2279.1208 1.15 91128 24814 3 2279.116265 760.7142 Thyroid receptor-interacting protein 11 OS=Homo sapiens OX=9606 GN=TRIP11 PE=1 SV=3 6.74 3751.1 - 5.89E+06 - - - -1.9964 - 3.866 0.65 - 341.6 1 2 0 -0.0046 20 0 0 0 1.90E+08 1.66E+08 - - - 9.0661 0.9811 221125_WJC_METTL3_EV_vs_WT_F06.24819.24819.4 2.89E-08 28/174 R.HIADLAGNSEVILPVPAFNVINGGSHAGNK.L "sp|P06733|ENOA_HUMAN,tr|A0A2R8Y6G6|A0A2R8Y6G6_HUMAN,tr|K7EM90|K7EM90_HUMAN,tr|A0A2R8YEM5|A0A2R8YEM5_HUMAN" 4 3010.5625 0.82 91129 24819 4 3011.549468 753.6479 Alpha-enolase OS=Homo sapiens OX=9606 GN=ENO1 PE=1 SV=2 5.99 3751.9 - 3.79E+06 - - - 327.8457 - 4.065 0.524 - 362.9 1 2 0 0.987 30 0 0 0 1.25E+07 1.52E+07 - - - 3.9426 1 221125_WJC_METTL3_EV_vs_WT_F06.24840.24840.3 7.84E-06 23/76 K.HAASDVDLEIESLLNQQSTK[136.11].E "sp|Q86U44|MTA70_HUMAN,tr|F5H6D8|F5H6D8_HUMAN,tr|H0YFV6|H0YFV6_HUMAN,tr|B4DTN4|B4DTN4_HUMAN" 4 2205.1005 0.05 91138 24840 3 2206.096661 736.0408 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 4.31 3754.4 - 1.50E+07 - - - 451.7731 - 4.392 0.664 - 713.6 1 2 0 0.9962 20 0 0 0 4.76E+07 9.86E+08 - - - 9.257 1 221125_WJC_METTL3_EV_vs_WT_F06.24841.24841.4 4.50E-17 38/192 R.R[166.11]AEQDSTTVAAFASSLVSGLNSSASEPAK[136.11]EPAK[136.11].K "sp|Q86U44|MTA70_HUMAN,tr|F5H6D8|F5H6D8_HUMAN,tr|H0YFV6|H0YFV6_HUMAN,tr|B4DTN4|B4DTN4_HUMAN" 4 3331.6742 0.03 91139 24841 4 3332.681762 833.9258 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 4.87 3754.5 - 1.50E+06 - - - 302.4152 - 6.312 0.688 - 980.1 1 2 1 1.0075 33 0 0 0 1.61E+06 5.84E+07 - - - 5.4881 1 221125_WJC_METTL3_EV_vs_WT_F06.24843.24843.4 6.35E-13 27/126 K.NDWHGGAIVSALSQTGSLFK[136.11]PR[166.11].K "sp|P51398|RT29_HUMAN,tr|V9GYA7|V9GYA7_HUMAN,tr|V9GYJ9|V9GYJ9_HUMAN,tr|V9GZ03|V9GZ03_HUMAN,tr|V9GZ61|V9GZ61_HUMAN,tr|V9GYC9|V9GYC9_HUMAN" 6 2358.2199 1.53 91141 24843 4 2358.218372 590.5623 "28S ribosomal protein S29, mitochondrial OS=Homo sapiens OX=9606 GN=DAP3 PE=1 SV=1" 8.75 3754.7 - 1.56E+06 - - - -0.6683 - 4.49 0.657 - 667.2 1 2 0 -0.0016 22 0 0 0 3.54E+07 2.32E+07 - - - 5.4355 0.9998 221125_WJC_METTL3_EV_vs_WT_F06.24847.24847.4 6.97E-05 16/150 R.LVMGGPQQLYHLDAYIPLQINSHESK.A "sp|Q9NWS0|PIHD1_HUMAN,tr|M0QYA2|M0QYA2_HUMAN" 2 2950.5011 1.54 91143 24847 4 2950.503667 738.6326 PIH1 domain-containing protein 1 OS=Homo sapiens OX=9606 GN=PIH1D1 PE=1 SV=1 5.99 3755.2 - 1.84E+06 - - - 0.8653 - 2.893 0.378 - 81.3 1 2 0 0.0026 26 0 0 0 2.60E+07 1.69E+07 - - - 2.8505 0.9998 221125_WJC_METTL3_EV_vs_WT_F06.24852.24852.4 0.000419 24/150 R.SFGTEDRPTDRPIPPRDEVFEYIIFR.G "sp|Q8ND56|LS14A_HUMAN,tr|I3L4Q1|I3L4Q1_HUMAN,tr|A0A140TA76|A0A140TA76_HUMAN,tr|K7EMZ9|K7EMZ9_HUMAN" 4 3151.5727 1.1 91146 24852 4 3151.577792 788.9005 Protein LSM14 homolog A OS=Homo sapiens OX=9606 GN=LSM14A PE=1 SV=3 4.59 3755.9 - 1.82E+06 - - - 1.616 - 3.142 0.501 - 80 1 2 1 0.0051 26 0 0 0 1.47E+08 1.33E+08 - - - 3.9464 0.9998 221125_WJC_METTL3_EV_vs_WT_F06.24853.24853.4 0.0263 19/228 K.VEYTPYEEGLHSVDVTYDGSPVPSSPFQVPVTEGC[160.03]DPSR.V "sp|P21333|FLNA_HUMAN,tr|Q60FE5|Q60FE5_HUMAN" 2 4295.9481 0.89 91147 24853 4 4295.94221 1074.9943 Filamin-A OS=Homo sapiens OX=9606 GN=FLNA PE=1 SV=4 3.95 3756 - 1.17E+06 - - - -1.3746 - 3.25 0.39 - 69.6 1 2 0 -0.0059 39 0 0 0 2.21E+07 2.49E+07 - - - 2.9609 1 221125_WJC_METTL3_EV_vs_WT_F06.24862.24862.4 1.26E-11 28/126 K.NDWHGGAIVSALSQTGSLFKPR.K "sp|P51398|RT29_HUMAN,tr|V9GYA7|V9GYA7_HUMAN,tr|V9GYJ9|V9GYJ9_HUMAN,tr|V9GZ03|V9GZ03_HUMAN,tr|V9GZ61|V9GZ61_HUMAN,tr|V9GYC9|V9GYC9_HUMAN" 6 2340.1975 1.41 91154 24862 4 2340.2029 586.0566 "28S ribosomal protein S29, mitochondrial OS=Homo sapiens OX=9606 GN=DAP3 PE=1 SV=1" 8.75 3757.2 - 1.45E+06 - - - 2.3169 - 4.308 0.667 - 722.7 1 2 0 0.0054 22 0 0 0 3.39E+07 2.41E+07 - - - 5.5079 1 221125_WJC_METTL3_EV_vs_WT_F06.24865.24865.3 0.000129 Aug-44 R.LFPPQWIC[160.03]C[160.03]DIR[166.11].Y sp|Q86U44|MTA70_HUMAN 1 1613.7722 0.001 91157 24865 3 1613.774823 538.9313 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 5.82 3757.6 - 214499 - - - 1.6192 - 2.018 0.537 - 100 1 2 0 0.0026 12 0 0 0 0.00E+00 1.29E+07 - - - 6.4724 1 221125_WJC_METTL3_EV_vs_WT_F06.24869.24869.4 1.21E-10 30/120 R.REDIVDTMVFKPSDVMLVHFR.N "sp|Q8WWM7|ATX2L_HUMAN,tr|H3BSQ5|H3BSQ5_HUMAN,tr|H3BSK9|H3BSK9_HUMAN,tr|H3BUE3|H3BUE3_HUMAN,tr|H3BUF6|H3BUF6_HUMAN" 5 2533.2821 0.69 91159 24869 4 2533.290748 634.3278 Ataxin-2-like protein OS=Homo sapiens OX=9606 GN=ATXN2L PE=1 SV=2 5.43 3758.1 - 644668 - - - 3.3995 - 5.282 0.632 - 926.4 1 2 0 0.0086 21 0 0 0 1.10E+07 1.59E+07 - - - 5.2748 1 221125_WJC_METTL3_EV_vs_WT_F06.24870.24870.4 2.41E-12 32/138 K.LNDFRDEQIGQLQELMQEATKPNR.Q sp|Q9NRP4|SDHF3_HUMAN 1 2872.4138 1.47 91160 24870 4 2872.418678 719.1107 "Succinate dehydrogenase assembly factor 3, mitochondrial OS=Homo sapiens OX=9606 GN=SDHAF3 PE=1 SV=1" 4.51 3758.2 - 1.78E+06 - - - 1.7139 - 5.837 0.644 - 931.2 1 2 1 0.0049 24 0 0 0 1.51E+08 1.03E+08 - - - 5.3963 0.9999 221125_WJC_METTL3_EV_vs_WT_F06.24872.24872.4 4.04E-10 29/228 K.YFSSNPIIPSQSAASSAIAFQPVGTGGVQLC[160.03]GGGSTGSK.G "sp|Q15517|CDSN_HUMAN,tr|G8JLG2|G8JLG2_HUMAN,tr|Q2L6G8|Q2L6G8_HUMAN" 3 3784.8367 124.76 91162 24872 4 3784.851149 947.2164 Corneodesmosin OS=Homo sapiens OX=9606 GN=CDSN PE=1 SV=3 8.2 3758.5 - 956410 - - - 3.8298 - 4.818 0.586 - 344.4 1 2 0 0.0145 39 0 0 0 2.47E+07 1.98E+05 - - - 4.7787 1 221125_WJC_METTL3_EV_vs_WT_F06.24879.24879.3 1.99E-12 32/152 K.YFSSNPIIPSQSAASSAIAFQPVGTGGVQLC[160.03]GGGSTGSK.G "sp|Q15517|CDSN_HUMAN,tr|G8JLG2|G8JLG2_HUMAN,tr|Q2L6G8|Q2L6G8_HUMAN" 3 3784.8367 999 91167 24879 3 3784.843845 1262.6195 Corneodesmosin OS=Homo sapiens OX=9606 GN=CDSN PE=1 SV=3 8.2 3759.4 - 1.55E+06 - - - 1.8999 - 5.089 0.648 - 547.6 1 2 0 0.0072 39 0 0 0 1.80E+07 0.00E+00 - - - 9.5059 0.9994 221125_WJC_METTL3_EV_vs_WT_F06.24884.24884.2 1.21E-06 22-Sep R.LFPPQWIC[160.03]C[160.03]DIR[166.11].Y sp|Q86U44|MTA70_HUMAN 1 1613.7722 0.06 91171 24884 2 1613.777195 807.8934 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 5.82 3760 - 1.13E+06 - - - 3.089 - 1.952 0.532 - 225.2 1 2 0 0.005 12 0 0 0 3.70E+06 6.39E+07 - - - 4.7287 1 221125_WJC_METTL3_EV_vs_WT_F06.24889.24889.4 9.97E-17 31/198 R.FLNEHPGGEEVLLEQAGVDASESFEDVGHSSDAR.E "sp|O43169|CYB5B_HUMAN,tr|D6RFH4|D6RFH4_HUMAN,tr|H3BUX2|H3BUX2_HUMAN" 3 3626.6397 1.25 91175 24889 4 3626.642043 907.6672 Cytochrome b5 type B OS=Homo sapiens OX=9606 GN=CYB5B PE=1 SV=3 4.05 3760.6 - 1.58E+06 - - - 0.6383 - 5.97 0.682 - 592.4 1 2 0 0.0023 34 0 0 0 3.37E+08 2.69E+08 - - - 5.6943 1 221125_WJC_METTL3_EV_vs_WT_F06.24891.24891.4 6.30E-13 24/120 R.R[166.11]EDIVDTMVFK[136.11]PSDVMLVHFR[166.11].N "sp|Q8WWM7|ATX2L_HUMAN,tr|H3BSQ5|H3BSQ5_HUMAN,tr|H3BSK9|H3BSK9_HUMAN,tr|H3BUE3|H3BUE3_HUMAN,tr|H3BUF6|H3BUF6_HUMAN" 5 2561.3129 0.77 91177 24891 4 2561.322406 641.3355 Ataxin-2-like protein OS=Homo sapiens OX=9606 GN=ATXN2L PE=1 SV=2 5.43 3760.9 - 539795 - - - 3.7207 - 4.511 0.647 - 461 1 2 0 0.0095 21 0 0 0 1.05E+07 1.36E+07 - - - 5.353 1 221125_WJC_METTL3_EV_vs_WT_F06.24892.24892.3 2.82E-08 14/56 R.DYLHLPPEIVPATLR.R "sp|P46783|RS10_HUMAN,tr|A0A2R8Y6L3|A0A2R8Y6L3_HUMAN,tr|F6U211|F6U211_HUMAN,tr|A0A1W2PQS6|A0A1W2PQS6_HUMAN,tr|A0A2R8YFH6|A0A2R8YFH6_HUMAN,tr|A0A2R8Y7H1|A0A2R8Y7H1_HUMAN,tr|S4R435|S4R435_HUMAN" 7 1732.9512 1.42 91178 24892 3 1732.952795 578.6577 40S ribosomal protein S10 OS=Homo sapiens OX=9606 GN=RPS10 PE=1 SV=1 5.32 3761 - 502441 - - - 0.9169 - 2.92 0.562 - 150.1 1 2 0 0.0016 15 0 0 0 1.88E+07 1.33E+07 - - - 7.6015 0.9999 221125_WJC_METTL3_EV_vs_WT_F06.24893.24893.3 0.0172 Dec-56 R.DYLHLPPEIVPATLR[166.11].R "sp|P46783|RS10_HUMAN,tr|A0A2R8Y6L3|A0A2R8Y6L3_HUMAN,tr|F6U211|F6U211_HUMAN,tr|A0A1W2PQS6|A0A1W2PQS6_HUMAN,tr|A0A2R8YFH6|A0A2R8YFH6_HUMAN,tr|A0A2R8Y7H1|A0A2R8Y7H1_HUMAN,tr|S4R435|S4R435_HUMAN" 7 1742.9595 1.39 91179 24893 3 1742.963719 581.9938 40S ribosomal protein S10 OS=Homo sapiens OX=9606 GN=RPS10 PE=1 SV=1 5.32 3761.1 - 479256 - - - 2.4344 - 2.569 0.438 - 152.5 1 2 0 0.0042 15 0 0 0 1.84E+07 1.32E+07 - - - 5.8841 1 221125_WJC_METTL3_EV_vs_WT_F06.24899.24899.3 4.40E-13 18/116 R.ASGPDGEC[160.03]DSNGPGFYLYDLGSTHGTFLNK.T "sp|Q9BWU0|NADAP_HUMAN,tr|A0A087X0M4|A0A087X0M4_HUMAN" 2 3175.3829 0.67 91183 24899 3 3175.389986 1059.4682 Kanadaptin OS=Homo sapiens OX=9606 GN=SLC4A1AP PE=1 SV=1 4.22 3761.9 - 536793 - - - 2.2287 - 3.83 0.738 - 291.2 1 2 0 0.0071 30 0 0 0 3.48E+06 5.16E+06 - - - 9.8555 0.9047 221125_WJC_METTL3_EV_vs_WT_F06.24900.24900.2 0.874 14-Jun K.DIGFIK[136.11]LD.- "sp|P62273|RS29_HUMAN,tr|A0A087WTT6|A0A087WTT6_HUMAN" 2 927.5157 1.14 91184 24900 2 927.516328 464.7651 40S ribosomal protein S29 OS=Homo sapiens OX=9606 GN=RPS29 PE=1 SV=2 4.54 3762 - 403281 - - - 0.6943 - 0.868 0.292 - 64.3 1 2 1 0.0006 8 0 0 0 1.40E+07 1.23E+07 - - - 0.7706 1 221125_WJC_METTL3_EV_vs_WT_F06.24906.24906.3 6.20E-09 18/68 K.YVHYEIDAC[160.03]MDSEAPGSK[136.11].D "sp|Q86U44|MTA70_HUMAN,tr|H0YFV6|H0YFV6_HUMAN" 2 2078.8805 0.01 91188 24906 3 2079.884705 693.9674 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 4.31 3762.8 - 763616 - - - 483.0547 - 3.473 0.649 - 351.3 1 2 0 1.0042 18 0 0 0 2.11E+05 3.61E+07 - - - 8.5978 1 221125_WJC_METTL3_EV_vs_WT_F06.24911.24911.4 6.83E-13 26/174 K.MMVDK[136.11]DGDVTVTNDGATILSMMDVDHQIAK[136.11].L "sp|P48643|TCPE_HUMAN,tr|E9PCA1|E9PCA1_HUMAN,tr|B7ZAR1|B7ZAR1_HUMAN" 3 3265.531 1.3 91191 24911 4 3265.530328 817.39 T-complex protein 1 subunit epsilon OS=Homo sapiens OX=9606 GN=CCT5 PE=1 SV=1 4.11 3763.5 - 1.09E+06 - - - -0.1972 - 5.003 0.699 - 412.4 1 2 1 -0.0006 30 0 0 0 2.49E+07 1.91E+07 - - - 5.8026 1 221125_WJC_METTL3_EV_vs_WT_F06.24912.24912.3 2.32E-13 17/120 R.SSGGSGGGPLSHFYSGSPTSYFTSGLQAGLK[136.11].Q "tr|K7EQG2|K7EQG2_HUMAN,tr|E9PAU2|E9PAU2_HUMAN,tr|A0A087WZ13|A0A087WZ13_HUMAN" 3 2998.4188 0.91 91192 24912 3 2998.424613 1000.4802 Uncharacterized protein (Fragment) OS=Homo sapiens OX=9606 PE=1 SV=1 8.24 3763.6 - 581877 - - - 1.9287 - 3.534 0.711 - 237.5 1 2 0 0.0058 31 0 0 0 1.41E+09 1.55E+09 - - - 9.3697 1 221125_WJC_METTL3_EV_vs_WT_F06.24913.24913.3 3.47E-18 21/112 R.VQNTSLEAIVQNASSDNQGIQLSAVQAAR.K "sp|O00629|IMA3_HUMAN,tr|A0A7I2YQ95|A0A7I2YQ95_HUMAN,tr|H7C4F6|H7C4F6_HUMAN,tr|A0A7I2V340|A0A7I2V340_HUMAN,tr|A0A7I2V333|A0A7I2V333_HUMAN" 5 3011.5272 0.95 91193 24913 3 3011.544293 1004.8497 Importin subunit alpha-3 OS=Homo sapiens OX=9606 GN=KPNA4 PE=1 SV=1 4.37 3763.7 - 1.11E+06 - - - 5.6742 - 4.057 0.717 - 470.6 1 2 0 0.0171 29 0 0 0 4.50E+07 4.75E+07 - - - 9.751 0.9979 221125_WJC_METTL3_EV_vs_WT_F06.24921.24921.4 3.92E-10 23/234 Q.QFGAVGVAGSSLTSFGTETSNSGTLPQSSAVGSAFTQDTR[166.11].S "sp|Q8ND56|LS14A_HUMAN,tr|A0A140TA76|A0A140TA76_HUMAN,tr|K7EMZ9|K7EMZ9_HUMAN" 3 3916.8591 1.37 91199 24921 4 3916.856943 980.222 Protein LSM14 homolog A OS=Homo sapiens OX=9606 GN=LSM14A PE=1 SV=3 4.37 3764.7 - 1.03E+06 - - - -0.539 - 4.526 0.565 - 183.4 1 1 0 -0.0021 40 0 0 0 2.34E+07 1.71E+07 - - - 4.579 1 221125_WJC_METTL3_EV_vs_WT_F06.24923.24923.3 2.66E-15 17/120 R.SSGGSGGGPLSHFYSGSPTSYFTSGLQAGLK.Q "tr|K7EQG2|K7EQG2_HUMAN,tr|E9PAU2|E9PAU2_HUMAN,tr|A0A087WZ13|A0A087WZ13_HUMAN" 3 2990.4046 0.91 91201 24923 3 2990.407852 997.8088 Uncharacterized protein (Fragment) OS=Homo sapiens OX=9606 PE=1 SV=1 8.24 3764.9 - 700178 - - - 1.0774 - 3.592 0.696 - 217.7 1 2 0 0.0032 31 0 0 0 1.41E+09 1.55E+09 - - - 9.2407 1 221125_WJC_METTL3_EV_vs_WT_F06.24926.24926.4 8.92E-06 16/108 R.GLLQDDAHPTLVTYADHSK[136.11].L "sp|Q86U44|MTA70_HUMAN,tr|F5H6D8|F5H6D8_HUMAN,tr|H0YFV6|H0YFV6_HUMAN,tr|B4DTN4|B4DTN4_HUMAN" 4 2088.0367 0.01 91202 24926 4 2088.03836 523.0165 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 5.13 3765.5 - 645631 - - - 0.7792 - 3.217 0.519 - 274.5 1 2 0 0.0016 19 0 0 0 4.81E+05 4.24E+07 - - - 4.1382 0.9955 221125_WJC_METTL3_EV_vs_WT_F06.24929.24929.4 4.70E-08 24/234 Q.QFGAVGVAGSSLTSFGTETSNSGTLPQSSAVGSAFTQDTR.S "sp|Q8ND56|LS14A_HUMAN,tr|A0A140TA76|A0A140TA76_HUMAN,tr|K7EMZ9|K7EMZ9_HUMAN" 3 3906.8508 1.37 91204 24929 4 3906.857662 977.72 Protein LSM14 homolog A OS=Homo sapiens OX=9606 GN=LSM14A PE=1 SV=3 4.37 3765.8 - 816593 - - - 1.7605 - 4.509 0.511 - 164.9 1 1 0 0.0069 40 0 0 0 2.34E+07 1.71E+07 - - - 4.1066 1 221125_WJC_METTL3_EV_vs_WT_F06.24932.24932.4 7.95E-12 34/150 K.LQLVKEEYITSALESTEEKLHDAASK.L "sp|P52732|KIF11_HUMAN,tr|A0A7I2YQY4|A0A7I2YQY4_HUMAN,tr|A0A7I2V3A9|A0A7I2V3A9_HUMAN,tr|A0A7I2V3V3|A0A7I2V3V3_HUMAN" 4 2931.5077 9.35 91205 24932 4 2931.513551 733.8842 Kinesin-like protein KIF11 OS=Homo sapiens OX=9606 GN=KIF11 PE=1 SV=2 4.7 3766.2 - 2.20E+06 - - - 1.9966 - 5.994 0.608 - 1058.9 1 2 2 0.0059 26 0 0 0 6.21E+07 6.64E+06 - - - 5.0813 1 221125_WJC_METTL3_EV_vs_WT_F06.24933.24933.3 1.13E-11 19/112 R.VQNTSLEAIVQNASSDNQGIQLSAVQAAR[166.11].K "sp|O00629|IMA3_HUMAN,tr|A0A7I2YQ95|A0A7I2YQ95_HUMAN,tr|H7C4F6|H7C4F6_HUMAN,tr|A0A7I2V340|A0A7I2V340_HUMAN,tr|A0A7I2V333|A0A7I2V333_HUMAN" 5 3021.5355 0.95 91206 24933 3 3021.53786 1008.1858 Importin subunit alpha-3 OS=Homo sapiens OX=9606 GN=KPNA4 PE=1 SV=1 4.37 3766.3 - 1.49E+06 - - - 0.7893 - 3.785 0.66 - 260.8 1 2 0 0.0024 29 0 0 0 4.50E+07 4.75E+07 - - - 8.9599 1 221125_WJC_METTL3_EV_vs_WT_F06.24935.24935.3 1.46E-15 26/132 R.FLNEHPGGEEVLLEQAGVDASESFEDVGHSSDAR[166.11].E "sp|O43169|CYB5B_HUMAN,tr|D6RFH4|D6RFH4_HUMAN,tr|H3BUX2|H3BUX2_HUMAN" 3 3636.648 1.29 91208 24935 3 3636.659637 1213.2233 Cytochrome b5 type B OS=Homo sapiens OX=9606 GN=CYB5B PE=1 SV=3 4.05 3766.6 - 363985 - - - 3.2005 - 5.318 0.776 - 451.2 1 2 0 0.0116 34 0 0 0 1.14E+07 8.90E+06 - - - 11.033 0.9999 221125_WJC_METTL3_EV_vs_WT_F06.24941.24941.3 4.12E-06 14/100 K.ITVTFNINNSIPPTFDGEEEPSQGQK.V "sp|Q07021|C1QBP_HUMAN,tr|I3L3B0|I3L3B0_HUMAN,tr|I3L3Q7|I3L3Q7_HUMAN" 3 2861.3719 0.88 91212 24941 3 2861.37883 954.7979 "Complement component 1 Q subcomponent-binding protein, mitochondrial OS=Homo sapiens OX=9606 GN=C1QBP PE=1 SV=1" 4 3767.4 - 440942 - - - 2.4104 - 2.506 0.54 - 71.2 1 2 0 0.0069 26 0 0 0 9.14E+06 1.04E+07 - - - 6.6721 1 221125_WJC_METTL3_EV_vs_WT_F06.24942.24942.3 9.20E-14 25/112 R.DNSDFDLLTVSETANEPPQDEGNSFNSPR.N sp|O15371|EIF3D_HUMAN 1 3194.3912 1.35 91213 24942 3 3194.395381 1065.8044 Eukaryotic translation initiation factor 3 subunit D OS=Homo sapiens OX=9606 GN=EIF3D PE=1 SV=1 3.62 3767.5 - 1.93E+06 - - - 1.301 - 4.046 0.719 - 366.2 1 2 0 0.0042 29 0 0 0 1.79E+08 1.33E+08 - - - 9.7707 0.9895 221125_WJC_METTL3_EV_vs_WT_F06.24945.24945.4 0.319 24/150 K.SKELTTEIDNNIEQISSYKSEITELR.R "sp|P13645|K1C10_HUMAN,tr|A0A1B0GVI3|A0A1B0GVI3_HUMAN" 2 3039.5248 0.74 91216 24945 4 3040.520672 760.8885 "Keratin, type I cytoskeletal 10 OS=Homo sapiens OX=9606 GN=KRT10 PE=1 SV=6" 4.42 3767.9 - 444874 - - - 327.639 - 4.407 0.503 - 390.2 1 2 2 0.9959 26 0 0 0 1.03E+07 1.40E+07 - - - 3.7961 0.9999 221125_WJC_METTL3_EV_vs_WT_F06.24948.24948.4 6.47E-05 29/138 K.LNDFR[166.11]DEQIGQLQELMQEATK[136.11]PNR[166.11].Q sp|Q9NRP4|SDHF3_HUMAN 1 2900.4445 1.65 91217 24948 4 2900.449747 726.1184 "Succinate dehydrogenase assembly factor 3, mitochondrial OS=Homo sapiens OX=9606 GN=SDHAF3 PE=1 SV=1" 4.51 3768.3 - 2.80E+06 - - - 1.8108 - 5.015 0.606 - 682.6 1 2 1 0.0053 24 0 0 0 1.32E+08 7.99E+07 - - - 5.0167 1 221125_WJC_METTL3_EV_vs_WT_F06.24949.24949.3 0.0078 14/60 K.K[136.11]VSQEILELLNTTTAK[136.11].E "sp|Q86U44|MTA70_HUMAN,tr|H0YFV6|H0YFV6_HUMAN" 2 1803.0324 0.001 91218 24949 3 1803.034398 602.0181 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 6.14 3768.4 - 172774 - - - 1.0915 - 2.874 0.543 - 312.4 1 2 0 0.002 16 0 0 0 0.00E+00 7.33E+06 - - - 7.3022 0.9994 221125_WJC_METTL3_EV_vs_WT_F06.24950.24950.3 1.34E-05 14/72 R.GLLQDDAHPTLVTYADHSK[136.11].L "sp|Q86U44|MTA70_HUMAN,tr|F5H6D8|F5H6D8_HUMAN,tr|H0YFV6|H0YFV6_HUMAN,tr|B4DTN4|B4DTN4_HUMAN" 4 2088.0367 0.03 91219 24950 3 2088.045561 697.0195 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 5.13 3768.6 - 352357 - - - 4.2279 - 2.9 0.396 - 203.8 1 2 0 0.0088 19 0 0 0 4.25E+05 1.65E+07 - - - 5.5683 1 221125_WJC_METTL3_EV_vs_WT_F06.24953.24953.4 2.98E-08 17/114 R.DNAIPTIFDLTSHLNNPHSR[166.11].H "sp|O43422|P52K_HUMAN,tr|A0A804HKR8|A0A804HKR8_HUMAN,tr|A0A804HL83|A0A804HL83_HUMAN" 3 2271.1272 1.21 91220 24953 4 2271.130731 568.7891 52 kDa repressor of the inhibitor of the protein kinase OS=Homo sapiens OX=9606 GN=THAP12 PE=1 SV=2 5.98 3769 - 178438 - - - 1.571 - 3.401 0.607 - 195.2 1 2 0 0.0036 20 0 0 0 9.92E+06 8.18E+06 - - - 4.9176 0.9989 221125_WJC_METTL3_EV_vs_WT_F06.24958.24958.4 2.23E-09 23/156 K.INQLSELADPLKDELNLADSEVDNQKR.G sp|Q96SB8|SMC6_HUMAN 1 3066.5469 0.67 91221 24958 4 3066.562241 767.644 Structural maintenance of chromosomes protein 6 OS=Homo sapiens OX=9606 GN=SMC6 PE=1 SV=2 4.14 3769.7 - 1.04E+06 - - - 4.9906 - 4.213 0.545 - 122.7 1 2 1 0.0153 27 0 0 0 8.86E+06 1.31E+07 - - - 4.4154 0.997 221125_WJC_METTL3_EV_vs_WT_F06.24965.24965.4 2.70E-10 18/192 K.VHIEFTEGEDK[136.11]ITLEGPTEDVNVAQEQIEGMVK[136.11].D "sp|Q00341|VIGLN_HUMAN,tr|A0A024R4E5|A0A024R4E5_HUMAN,tr|H7C0A4|H7C0A4_HUMAN,tr|H0Y394|H0Y394_HUMAN" 4 3699.816 1.24 91226 24965 4 3700.826325 925.9613 Vigilin OS=Homo sapiens OX=9606 GN=HDLBP PE=1 SV=2 4.1 3770.7 - 383948 - - - 273.0641 - 3.637 0.615 - 66.3 1 2 1 1.0103 33 0 0 0 4.48E+06 3.61E+06 - - - 4.6865 1 221125_WJC_METTL3_EV_vs_WT_F06.24969.24969.3 2.84E-09 24/92 K.LNDFRDEQIGQLQELMQEATKPNR.Q sp|Q9NRP4|SDHF3_HUMAN 1 2872.4138 7.57 91228 24969 3 2872.413405 958.4785 "Succinate dehydrogenase assembly factor 3, mitochondrial OS=Homo sapiens OX=9606 GN=SDHAF3 PE=1 SV=1" 4.51 3771.3 - 747694 - - - -0.1218 - 5.008 0.641 - 571.7 1 2 1 -0.0003 24 0 0 0 2.09E+07 2.76E+06 - - - 9.4282 0.9998 221125_WJC_METTL3_EV_vs_WT_F06.24970.24970.3 0.000109 Oct-68 R.IGPYQPNVPVGIDYVIPK[136.11].T "sp|P43243|MATR3_HUMAN,tr|B3KM87|B3KM87_HUMAN,tr|A8MXP9|A8MXP9_HUMAN,tr|A0A0R4J2E8|A0A0R4J2E8_HUMAN" 4 1976.0863 1.25 91229 24970 3 1976.092353 659.7027 Matrin-3 OS=Homo sapiens OX=9606 GN=MATR3 PE=1 SV=2 5.83 3771.4 - 291767 - - - 3.0884 - 2.465 0.46 - 113 1 2 0 0.0061 18 0 0 0 1.35E+07 1.08E+07 - - - 5.9134 0.9999 221125_WJC_METTL3_EV_vs_WT_F06.24973.24973.4 1.14E-08 23/150 K.DR[166.11]VTGQHQGYGFVEFLSEEDADYAIK[136.11].L "sp|Q15427|SF3B4_HUMAN,tr|Q5SZ64|Q5SZ64_HUMAN" 2 2991.4006 0.26 91230 24973 4 2991.404715 748.8574 Splicing factor 3B subunit 4 OS=Homo sapiens OX=9606 GN=SF3B4 PE=1 SV=1 4.29 3771.8 - 1.69E+06 - - - 1.392 - 3.592 0.584 - 315.3 1 2 1 0.0042 26 0 0 0 7.34E+06 2.86E+07 - - - 4.7113 1 221125_WJC_METTL3_EV_vs_WT_F06.24992.24992.3 1.20E-18 32/88 K.K[136.11]VSQEILELLNTTTAK[136.11]EQSIVEK[136.11].F "sp|Q86U44|MTA70_HUMAN,tr|H0YFV6|H0YFV6_HUMAN" 2 2624.4699 0.001 91244 24992 3 2624.467993 875.8306 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 4.95 3774.1 - 1.71E+06 - - - -0.7125 - 5.769 0.732 - 1431.5 1 2 1 -0.0019 23 0 0 0 0.00E+00 2.05E+08 - - - 10.8118 0.9999 221125_WJC_METTL3_EV_vs_WT_F06.24993.24993.4 2.29E-10 32/132 K.K[136.11]VSQEILELLNTTTAK[136.11]EQSIVEK[136.11].F "sp|Q86U44|MTA70_HUMAN,tr|H0YFV6|H0YFV6_HUMAN" 2 2624.4699 0.01 91245 24993 4 2624.470785 657.1247 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 4.95 3774.2 - 3.00E+06 - - - 0.3513 - 5.136 0.586 - 894 1 2 1 0.0009 23 0 0 0 1.67E+06 2.64E+08 - - - 4.8564 1 221125_WJC_METTL3_EV_vs_WT_F06.24995.24995.4 2.82E-05 15/120 K.ESHATLVFHNLLGEIDQQYSR[166.11].F "sp|P40763|STAT3_HUMAN,tr|A0A7I2V4F6|A0A7I2V4F6_HUMAN,tr|A0A7I2YQI1|A0A7I2YQI1_HUMAN,tr|A0A7I2YQD2|A0A7I2YQD2_HUMAN,tr|A0A7I2V3V0|A0A7I2V3V0_HUMAN,tr|A0A7I2V4C8|A0A7I2V4C8_HUMAN,tr|A0A7I2V4R3|A0A7I2V4R3_HUMAN,tr|A0A7I2V395|A0A7I2V395_HUMAN,tr|A0A7I2YQR5|A0A7I2YQR5_HUMAN,tr|A0A7I2V552|A0A7I2V552_HUMAN,tr|A0A7I2V2T1|A0A7I2V2T1_HUMAN,tr|A0A7I2V2G1|A0A7I2V2G1_HUMAN,tr|A0A7I2V444|A0A7I2V444_HUMAN,tr|A0A7I2V4R2|A0A7I2V4R2_HUMAN,tr|A0A7I2V5N9|A0A7I2V5N9_HUMAN" 15 2466.2167 0.56 91247 24995 4 2466.215037 617.5615 Signal transducer and activator of transcription 3 OS=Homo sapiens OX=9606 GN=STAT3 PE=1 SV=2 5.28 3774.4 - 517749 - - - -0.6772 - 2.746 0.479 - 163.9 1 2 0 -0.0017 21 0 0 0 6.81E+06 1.22E+07 - - - 3.7287 0.9997 221125_WJC_METTL3_EV_vs_WT_F06.24996.24996.2 0.00014 Dec-34 R.IGPYQPNVPVGIDYVIPK.T "sp|P43243|MATR3_HUMAN,tr|B3KM87|B3KM87_HUMAN,tr|A8MXP9|A8MXP9_HUMAN,tr|A0A0R4J2E8|A0A0R4J2E8_HUMAN" 4 1968.072 3.12 91248 24996 2 1968.069708 985.0433 Matrin-3 OS=Homo sapiens OX=9606 GN=MATR3 PE=1 SV=2 5.83 3774.6 - 394095 - - - -1.19 - 1.901 0.445 - 267.5 1 2 0 -0.0023 18 0 0 0 9.11E+06 2.92E+06 - - - 3.9064 1 221125_WJC_METTL3_EV_vs_WT_F06.25001.25001.3 1.93E-18 28/104 R.ALYDAELSQMQTHISDTSVVLSMDNNR.N "sp|P48668|K2C6C_HUMAN,sp|P04259|K2C6B_HUMAN,sp|P02538|K2C6A_HUMAN" 3 3037.4121 999 91251 25001 3 3037.414989 1013.478 "Keratin, type II cytoskeletal 6C OS=Homo sapiens OX=9606 GN=KRT6C PE=1 SV=3" 4.22 3775.2 - 1.46E+06 - - - 0.9511 - 5.309 0.723 - 858.6 1 2 0 0.0029 27 0 0 0 6.37E+07 0.00E+00 - - - 10.4406 1 221125_WJC_METTL3_EV_vs_WT_F06.25012.25012.4 9.49E-18 32/204 K.ILQGNENGNFIISTDPNTNEGVLC[160.03]VVKPLNYEVNR.Q sp|Q08554|DSC1_HUMAN 1 3929.9582 4.23 91257 25012 4 3929.965824 983.4968 Desmocollin-1 OS=Homo sapiens OX=9606 GN=DSC1 PE=1 SV=2 4.41 3776.6 - 1.42E+06 - - - 1.9486 - 5.795 0.683 - 384.8 1 2 0 0.0077 35 0 0 0 2.09E+07 4.93E+06 - - - 5.6896 0.9992 221125_WJC_METTL3_EV_vs_WT_F06.25015.25015.4 4.48E-07 21/150 R.LALVHDMAEC[160.03]IVGDIAPADNIPKEEK.H "sp|Q7Z4H3|HDDC2_HUMAN,tr|V9GZ04|V9GZ04_HUMAN,tr|V9GYS5|V9GYS5_HUMAN" 3 2847.4147 0.71 91258 25015 4 2847.420189 712.8609 5'-deoxynucleotidase HDDC2 OS=Homo sapiens OX=9606 GN=HDDC2 PE=1 SV=1 4.29 3777 - 774901 - - - 1.9393 - 3.435 0.393 - 222.7 1 2 1 0.0055 26 0 0 0 1.11E+07 1.55E+07 - - - 3.0344 0.9999 221125_WJC_METTL3_EV_vs_WT_F06.25017.25017.3 1.02E-05 15/56 R.NIETIINTFHQYSVK.L sp|P06702|S10A9_HUMAN 1 1805.9312 31 91260 25017 3 1805.93561 602.9843 Protein S100-A9 OS=Homo sapiens OX=9606 GN=S100A9 PE=1 SV=1 6.75 3777.3 - 609144 - - - 2.4425 - 2.843 0.475 - 207.2 1 2 0 0.0044 15 0 0 0 4.25E+07 1.37E+06 - - - 6.561 0.9995 221125_WJC_METTL3_EV_vs_WT_F06.25026.25026.4 6.43E-06 24/240 R.DATWSPLNHSLLTTVGWDHQVVHHVVPTEPLPAPGPASVTE.- "sp|Q9BQA1|MEP50_HUMAN,tr|H0Y711|H0Y711_HUMAN" 2 4391.1975 - 91265 25026 4 4391.203897 1098.8066 Methylosome protein 50 OS=Homo sapiens OX=9606 GN=WDR77 PE=1 SV=1 5.25 3778.5 - 928256 - - - 1.4602 - 2.806 0.33 - 124.6 1 2 0 0.0064 41 0 0 0 - - - - - 2.3929 0.9999 221125_WJC_METTL3_EV_vs_WT_F06.25029.25029.4 9.75E-05 14/120 K.ESHATLVFHNLLGEIDQQYSR.F "sp|P40763|STAT3_HUMAN,tr|A0A7I2V4F6|A0A7I2V4F6_HUMAN,tr|A0A7I2YQI1|A0A7I2YQI1_HUMAN,tr|A0A7I2YQD2|A0A7I2YQD2_HUMAN,tr|A0A7I2V3V0|A0A7I2V3V0_HUMAN,tr|A0A7I2V4C8|A0A7I2V4C8_HUMAN,tr|A0A7I2V4R3|A0A7I2V4R3_HUMAN,tr|A0A7I2V395|A0A7I2V395_HUMAN,tr|A0A7I2YQR5|A0A7I2YQR5_HUMAN,tr|A0A7I2V552|A0A7I2V552_HUMAN,tr|A0A7I2V2T1|A0A7I2V2T1_HUMAN,tr|A0A7I2V2G1|A0A7I2V2G1_HUMAN,tr|A0A7I2V444|A0A7I2V444_HUMAN,tr|A0A7I2V4R2|A0A7I2V4R2_HUMAN,tr|A0A7I2V5N9|A0A7I2V5N9_HUMAN" 15 2456.2084 0.56 91268 25029 4 2456.211885 615.0594 Signal transducer and activator of transcription 3 OS=Homo sapiens OX=9606 GN=STAT3 PE=1 SV=2 5.28 3778.9 - 380450 - - - 1.4038 - 2.731 0.407 - 161.8 1 2 0 0.0034 21 0 0 0 6.81E+06 1.22E+07 - - - 3.0998 0.9999 221125_WJC_METTL3_EV_vs_WT_F06.25043.25043.3 8.47E-10 17/88 M.PTTQQSPQDEQEK[136.11]LLDEAIQAVK[136.11].V "sp|Q96QK1|VPS35_HUMAN,tr|I3L4S0|I3L4S0_HUMAN,tr|A0A1W2PP10|A0A1W2PP10_HUMAN,tr|A0A3B3ITD4|A0A3B3ITD4_HUMAN" 4 2611.3312 0.76 91276 25043 3 2611.326718 871.451 Vacuolar protein sorting-associated protein 35 OS=Homo sapiens OX=9606 GN=VPS35 PE=1 SV=2 4.18 3780.7 - 518529 - - - -1.7129 - 4.014 0.519 - 450.8 1 2 1 -0.0045 23 0 0 0 1.69E+07 2.21E+07 - - - 7.5855 1 221125_WJC_METTL3_EV_vs_WT_F06.25044.25044.3 8.51E-12 25/72 K.NKLNDLEDALQQAKEDLAR.L sp|P04264|K2C1_HUMAN 1 2183.1182 999 91277 25044 3 2183.118348 728.7134 "Keratin, type II cytoskeletal 1 OS=Homo sapiens OX=9606 GN=KRT1 PE=1 SV=6" 4.44 3780.8 - 447416 - - - 0.0563 - 5.171 0.628 - 1113.3 1 2 2 0.0001 19 0 0 0 5.33E+09 0.00E+00 - - - 9.5782 1 221125_WJC_METTL3_EV_vs_WT_F06.25050.25050.3 6.83E-14 25/112 R.DNSDFDLLTVSETANEPPQDEGNSFNSPR[166.11].N sp|O15371|EIF3D_HUMAN 1 3204.3995 1.35 91281 25050 3 3204.397575 1069.1404 Eukaryotic translation initiation factor 3 subunit D OS=Homo sapiens OX=9606 GN=EIF3D PE=1 SV=1 3.62 3781.6 - 1.06E+06 - - - -0.5992 - 4.204 0.688 - 416.7 1 2 0 -0.0019 29 0 0 0 1.79E+08 1.33E+08 - - - 9.5138 0.996 221125_WJC_METTL3_EV_vs_WT_F06.25051.25051.4 1.41E-07 18/108 A.K[136.11]GHYTEGAELVDSVLDVVR[166.11].K "sp|Q9BVA1|TBB2B_HUMAN,sp|P07437|TBB5_HUMAN,sp|Q13509|TBB3_HUMAN,sp|Q13885|TBB2A_HUMAN,sp|P68371|TBB4B_HUMAN,tr|A0A0B4J269|A0A0B4J269_HUMAN,tr|Q5ST81|Q5ST81_HUMAN,tr|Q5JP53|Q5JP53_HUMAN,tr|G3V2A3|G3V2A3_HUMAN" 9 2104.092 0.57 91282 25051 4 2104.096666 527.0303 Tubulin beta-2B chain OS=Homo sapiens OX=9606 GN=TUBB2B PE=1 SV=1 4.75 3781.7 - 286841 - - - 2.2394 - 3.467 0.561 - 276.5 1 1 0 0.0047 19 0 0 0 2.79E+07 4.91E+07 - - - 4.5282 0.9999 221125_WJC_METTL3_EV_vs_WT_F06.25055.25055.4 1.75E-05 17/108 K.NKLNDLEDALQQAKEDLAR.L sp|P04264|K2C1_HUMAN 1 2183.1182 3687.92 91283 25055 4 2183.117708 546.7868 "Keratin, type II cytoskeletal 1 OS=Homo sapiens OX=9606 GN=KRT1 PE=1 SV=6" 4.44 3782.3 - 3.49E+06 - - - -0.2368 - 3.421 0.552 - 198.8 1 2 2 -0.0005 19 0 0 0 2.00E+09 5.42E+05 - - - 4.4465 0.9967 221125_WJC_METTL3_EV_vs_WT_F06.25064.25064.3 2.37E-09 18/72 A.KGHYTEGAELVDSVLDVVR.K "sp|Q9BVA1|TBB2B_HUMAN,sp|P07437|TBB5_HUMAN,sp|Q13509|TBB3_HUMAN,sp|Q13885|TBB2A_HUMAN,sp|P68371|TBB4B_HUMAN,tr|A0A0B4J269|A0A0B4J269_HUMAN,tr|Q5ST81|Q5ST81_HUMAN,tr|Q5JP53|Q5JP53_HUMAN,tr|G3V2A3|G3V2A3_HUMAN" 9 2086.0695 0.6 91287 25064 3 2086.063915 696.3638 Tubulin beta-2B chain OS=Homo sapiens OX=9606 GN=TUBB2B PE=1 SV=1 4.75 3783.4 - 390818 - - - -2.6696 - 3.668 0.576 - 428.1 1 1 0 -0.0056 19 0 0 0 1.99E+07 3.33E+07 - - - 8.1533 0.9998 221125_WJC_METTL3_EV_vs_WT_F06.25070.25070.2 6.33E-06 22-Nov K.ADTLTDEINFLR.A "sp|P48668|K2C6C_HUMAN,sp|P04259|K2C6B_HUMAN,sp|P02538|K2C6A_HUMAN" 3 1406.7042 3.95 91288 25070 2 1406.70404 704.3594 "Keratin, type II cytoskeletal 6C OS=Homo sapiens OX=9606 GN=KRT6C PE=1 SV=3" 4.03 3784.2 - 1.19E+06 - - - -0.0846 - 2.324 0.364 - 438.5 1 2 0 -0.0001 12 0 0 0 3.60E+07 9.13E+06 - - - 3.9483 1 221125_WJC_METTL3_EV_vs_WT_F06.25075.25075.2 1.04E-06 16/22 E.DALQQAKEDLAR.L sp|P04264|K2C1_HUMAN 1 1356.6997 199.95 91289 25075 2 1356.698059 679.3571 "Keratin, type II cytoskeletal 1 OS=Homo sapiens OX=9606 GN=KRT1 PE=1 SV=6" 4.56 3785 - 1.13E+06 - - - -1.2412 - 2.755 0.562 - 1146.9 1 1 1 -0.0017 12 0 0 0 5.69E+07 2.85E+05 - - - 5.8579 0.997 221125_WJC_METTL3_EV_vs_WT_F06.25078.25078.4 7.95E-11 23/108 A.KGHYTEGAELVDSVLDVVR.K "sp|Q9BVA1|TBB2B_HUMAN,sp|P07437|TBB5_HUMAN,sp|Q13509|TBB3_HUMAN,sp|Q13885|TBB2A_HUMAN,sp|P68371|TBB4B_HUMAN,tr|A0A0B4J269|A0A0B4J269_HUMAN,tr|Q5ST81|Q5ST81_HUMAN,tr|Q5JP53|Q5JP53_HUMAN,tr|G3V2A3|G3V2A3_HUMAN" 9 2086.0695 0.57 91290 25078 4 2086.065459 522.5246 Tubulin beta-2B chain OS=Homo sapiens OX=9606 GN=TUBB2B PE=1 SV=1 4.75 3785.4 - 2.70E+06 - - - -1.9295 - 3.978 0.56 - 421 1 1 0 -0.004 19 0 0 0 2.79E+07 4.91E+07 - - - 4.5662 1 221125_WJC_METTL3_EV_vs_WT_F06.25081.25081.4 3.64E-13 31/168 K.LKEQEC[160.03]DVKDYGDLPFADIPNDSPFQIVK.N "sp|P05089|ARGI1_HUMAN,tr|A0A5F9ZH78|A0A5F9ZH78_HUMAN" 2 3379.6282 156.23 91292 25081 4 3379.620527 845.9143 Arginase-1 OS=Homo sapiens OX=9606 GN=ARG1 PE=1 SV=2 4.09 3785.8 - 2.61E+06 - - - -2.2778 - 4.208 0.658 - 444.5 1 2 2 -0.0077 29 0 0 0 1.07E+08 6.84E+05 - - - 5.394 1 221125_WJC_METTL3_EV_vs_WT_F06.25082.25082.3 4.64E-07 22/76 K.HAASDVDLEIESLLNQQSTK[136.11].E "sp|Q86U44|MTA70_HUMAN,tr|F5H6D8|F5H6D8_HUMAN,tr|H0YFV6|H0YFV6_HUMAN,tr|B4DTN4|B4DTN4_HUMAN" 4 2205.1005 0.05 91293 25082 3 2206.097571 736.0408 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 4.31 3785.8 - 4.30E+06 - - - 452.1857 - 4.088 0.648 - 645.3 1 2 0 0.9971 20 0 0 0 1.45E+07 2.77E+08 - - - 8.9043 0.9998 221125_WJC_METTL3_EV_vs_WT_F06.25086.25086.3 4.87E-09 17/88 M.PTTQQSPQDEQEKLLDEAIQAVK.V "sp|Q96QK1|VPS35_HUMAN,tr|I3L4S0|I3L4S0_HUMAN,tr|A0A1W2PP10|A0A1W2PP10_HUMAN,tr|A0A3B3ITD4|A0A3B3ITD4_HUMAN" 4 2595.3028 0.76 91295 25086 3 2595.296441 866.1082 Vacuolar protein sorting-associated protein 35 OS=Homo sapiens OX=9606 GN=VPS35 PE=1 SV=2 4.18 3786.4 - 728846 - - - -2.4467 - 3.563 0.558 - 296.7 1 2 1 -0.0063 23 0 0 0 1.69E+07 2.21E+07 - - - 7.7402 1 221125_WJC_METTL3_EV_vs_WT_F06.25087.25087.2 3.21E-16 26/36 K.NKLNDLEDALQQAKEDLAR.L sp|P04264|K2C1_HUMAN 1 2183.1182 999 91296 25087 2 2183.115717 1092.5664 "Keratin, type II cytoskeletal 1 OS=Homo sapiens OX=9606 GN=KRT1 PE=1 SV=6" 4.44 3786.5 - 2.67E+06 - - - -1.1488 - 4.836 0.652 - 1539.4 1 2 2 -0.0025 19 0 0 0 6.77E+07 0.00E+00 - - - 7.7308 1 221125_WJC_METTL3_EV_vs_WT_F06.25096.25096.3 2.10E-14 25/104 K.VLYDAEISQIHQSVTDTNVILSMDNSR.N sp|P35908|K22E_HUMAN 1 3047.487 101.5 91298 25096 3 3047.480494 1016.8363 "Keratin, type II cytoskeletal 2 epidermal OS=Homo sapiens OX=9606 GN=KRT2 PE=1 SV=2" 4.22 3787.9 - 2.66E+06 - - - -2.1283 - 4.959 0.672 - 512.8 1 2 0 -0.0065 27 0 0 0 5.34E+07 5.26E+05 - - - 9.7141 1 221125_WJC_METTL3_EV_vs_WT_F06.25102.25102.4 1.31E-08 40/216 K.KGSITSVQAIYVPADDLTDPAPATTFAHLDATTVLSR.A "sp|P06576|ATPB_HUMAN,tr|H0YI37|H0YI37_HUMAN,tr|H0YH81|H0YH81_HUMAN" 3 3841.9738 1.77 91300 25102 4 3841.97383 961.5007 "ATP synthase subunit beta, mitochondrial OS=Homo sapiens OX=9606 GN=ATP5F1B PE=1 SV=3" 4.56 3788.7 - 4.53E+06 - - - 0.0081 - 5.524 0.685 - 860.1 1 2 0 0 37 0 0 0 1.30E+08 7.36E+07 - - - 5.6893 1 221125_WJC_METTL3_EV_vs_WT_F06.25106.25106.4 5.71E-16 46/216 K.K[136.11]GSITSVQAIYVPADDLTDPAPATTFAHLDATTVLSR[166.11].A "sp|P06576|ATPB_HUMAN,tr|H0YI37|H0YI37_HUMAN,tr|H0YH81|H0YH81_HUMAN" 3 3859.9963 1.77 91302 25106 4 3859.989219 966.0063 "ATP synthase subunit beta, mitochondrial OS=Homo sapiens OX=9606 GN=ATP5F1B PE=1 SV=3" 4.56 3789.3 - 4.08E+06 - - - -1.8264 - 5.785 0.701 - 1237.4 1 2 0 -0.007 37 0 0 0 1.30E+08 7.36E+07 - - - 5.8401 0.9999 221125_WJC_METTL3_EV_vs_WT_F06.25111.25111.4 1.36E-10 15/168 K.AK[136.11]VDEFPLC[160.03]GHMVSDEYEQLSSEALEAAR[166.11].L "sp|P27635|RL10_HUMAN,tr|A6QRI9|A6QRI9_HUMAN,tr|B8A6G2|B8A6G2_HUMAN,tr|X1WI28|X1WI28_HUMAN" 4 3298.5241 0.87 91305 25111 4 3298.516749 825.6383 60S ribosomal protein L10 OS=Homo sapiens OX=9606 GN=RPL10 PE=1 SV=4 4.25 3789.9 - 2.09E+06 - - - -2.2328 - 3.168 0.62 - 105 1 2 1 -0.0074 29 0 0 0 2.85E+07 3.29E+07 - - - 4.9758 0.9997 221125_WJC_METTL3_EV_vs_WT_F06.25112.25112.4 0.000126 17/108 R.NMQDLVEDLKNKYEDEINK.R "sp|P48668|K2C6C_HUMAN,sp|P04259|K2C6B_HUMAN" 2 2337.1158 99.54 91306 25112 4 2337.117388 585.2862 "Keratin, type II cytoskeletal 6C OS=Homo sapiens OX=9606 GN=KRT6C PE=1 SV=3" 4.3 3790 - 1.35E+06 - - - 0.6615 - 2.407 0.45 - 86.3 1 2 2 0.0015 19 0 0 0 1.21E+07 1.22E+05 - - - 3.4395 1 221125_WJC_METTL3_EV_vs_WT_F06.25128.25128.4 4.01E-19 35/210 K.QPATVGMAEGNFSGSQPYLQSFPNLAAGSLLVGHHK.Q sp|Q9HCJ3|RAVR2_HUMAN 1 3709.8311 1.56 91316 25128 4 3709.830808 928.4651 Ribonucleoprotein PTB-binding 2 OS=Homo sapiens OX=9606 GN=RAVER2 PE=1 SV=2 6.92 3791.9 - 2.53E+06 - - - -0.0828 - 5.66 0.645 - 622 1 2 0 -0.0003 36 0 0 0 6.03E+07 3.86E+07 - - - 5.351 0.9999 221125_WJC_METTL3_EV_vs_WT_F06.25132.25132.4 8.08E-11 35/252 K.ALANVNIGSLIC[160.03]NVGAGGPAPAAGAAPAGGPAPSTAAAPAEEK.K sp|P05386|RLA1_HUMAN 1 3807.9214 2.57 91318 25132 4 3807.935032 952.9876 60S acidic ribosomal protein P1 OS=Homo sapiens OX=9606 GN=RPLP1 PE=1 SV=1 4.53 3792.5 - 1.95E+06 - - - 3.5833 - 5.27 0.58 - 412.8 1 2 0 0.0136 43 0 0 0 2.55E+07 9.95E+06 - - - 4.7436 0.9998 221125_WJC_METTL3_EV_vs_WT_F06.25134.25134.4 0.000908 25/156 R.IRSEDEEDLGNARPSAPSTLFDFLESK.M sp|Q9H7E2|TDRD3_HUMAN 1 3022.452 0.4 91320 25134 4 3022.461658 756.6203 Tudor domain-containing protein 3 OS=Homo sapiens OX=9606 GN=TDRD3 PE=1 SV=1 4.2 3792.7 - 2.08E+06 - - - 3.204 - 4.372 0.602 - 380.7 1 2 1 0.0097 27 0 0 0 1.33E+07 3.33E+07 - - - 4.9247 1 221125_WJC_METTL3_EV_vs_WT_F06.25138.25138.3 6.70E-13 27/120 K.TSEQLDQPISAC[160.03]C[160.03]FNHNGNIFAYASSYDWSK.G "sp|P78406|RAE1L_HUMAN,tr|E9PQ57|E9PQ57_HUMAN" 2 3609.5565 3.06 91322 25138 3 3609.560287 1204.1928 mRNA export factor OS=Homo sapiens OX=9606 GN=RAE1 PE=1 SV=1 4.53 3793.2 - 1.90E+06 - - - 1.04 - 5.231 0.716 - 702 1 2 0 0.0038 31 0 0 0 3.86E+07 1.26E+07 - - - 10.3283 1 221125_WJC_METTL3_EV_vs_WT_F06.25141.25141.4 1.07E-07 22/180 K.TSEQLDQPISAC[160.03]C[160.03]FNHNGNIFAYASSYDWSK.G "sp|P78406|RAE1L_HUMAN,tr|E9PQ57|E9PQ57_HUMAN" 2 3609.5565 2.41 91325 25141 4 3609.561699 903.3964 mRNA export factor OS=Homo sapiens OX=9606 GN=RAE1 PE=1 SV=1 4.53 3793.6 - 1.92E+06 - - - 1.4312 - 3.81 0.549 - 247.7 1 2 0 0.0052 31 0 0 0 2.68E+07 1.11E+07 - - - 4.4096 1 221125_WJC_METTL3_EV_vs_WT_F06.25144.25144.3 2.11E-13 25/120 R.SSGGSGGGPLSHFYSGSPTSYFTSGLQAGLK[136.11].Q "tr|K7EQG2|K7EQG2_HUMAN,tr|E9PAU2|E9PAU2_HUMAN,tr|A0A087WZ13|A0A087WZ13_HUMAN" 3 2998.4188 0.91 91327 25144 3 2998.42188 1000.4802 Uncharacterized protein (Fragment) OS=Homo sapiens OX=9606 PE=1 SV=1 8.24 3793.9 - 1.15E+06 - - - 1.0172 - 4.305 0.668 - 517.7 1 2 0 0.0031 31 0 0 0 1.41E+09 1.55E+09 - - - 9.3451 1 221125_WJC_METTL3_EV_vs_WT_F06.25146.25146.3 8.21E-12 17/104 K.EKKEEQVISLGPQVAEGENVFGVC[160.03]HIF.A "sp|P62263|RS14_HUMAN,tr|A0A2R8Y811|A0A2R8Y811_HUMAN,tr|E5RH77|E5RH77_HUMAN" 3 3042.5121 0.8 91328 25146 3 3042.523094 1015.178 40S ribosomal protein S14 OS=Homo sapiens OX=9606 GN=RPS14 PE=1 SV=3 4.64 3794.2 - 625543 - - - 3.6227 - 3.483 0.643 - 315.8 1 1 1 0.011 27 0 0 0 1.28E+07 1.59E+07 - - - 8.5767 0.9982 221125_WJC_METTL3_EV_vs_WT_F06.25147.25147.3 2.01E-08 14/128 R.AEQDSTTVAAFASSLVSGLNSSASEPAK[136.11]EPAK[136.11]K[136.11].S "sp|Q86U44|MTA70_HUMAN,tr|F5H6D8|F5H6D8_HUMAN,tr|H0YFV6|H0YFV6_HUMAN,tr|B4DTN4|B4DTN4_HUMAN" 4 3301.674 0.08 91329 25147 3 3301.657521 1101.5653 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 4.87 3794.3 - 232077 - - - -4.9896 - 2.626 0.539 - 131 1 2 1 -0.0165 33 0 0 0 3.00E+05 3.56E+06 - - - 6.7659 1 221125_WJC_METTL3_EV_vs_WT_F06.25148.25148.3 5.65E-07 23/100 K.TR[166.11]YDSGQDLDEEGMNMGDFDPNNIFK[136.11].A "sp|Q99615|DNJC7_HUMAN,tr|A0A6I8PRZ0|A0A6I8PRZ0_HUMAN,tr|A0A6I8PIK4|A0A6I8PIK4_HUMAN,tr|A0A6I8PS32|A0A6I8PS32_HUMAN,tr|A0A6I8PUD4|A0A6I8PUD4_HUMAN,tr|K7ER44|K7ER44_HUMAN,tr|A0A6I8PU73|A0A6I8PU73_HUMAN" 7 3025.2825 0.69 91330 25148 3 3025.276466 1009.4348 DnaJ homolog subfamily C member 7 OS=Homo sapiens OX=9606 GN=DNAJC7 PE=1 SV=2 3.85 3794.4 - 794324 - - - -1.9899 - 3.925 0.62 - 421.3 1 2 1 -0.006 26 0 0 0 4.26E+06 6.21E+06 - - - 8.5965 0.9997 221125_WJC_METTL3_EV_vs_WT_F06.25152.25152.4 3.22E-05 19/150 R.VDTVNHLADELINSGHSDAATIAEWK.D "sp|Q01082|SPTB2_HUMAN,tr|A0A087WUZ3|A0A087WUZ3_HUMAN" 2 2805.357 9.74 91333 25152 4 2805.346505 702.3465 "Spectrin beta chain, non-erythrocytic 1 OS=Homo sapiens OX=9606 GN=SPTBN1 PE=1 SV=2" 4.42 3794.9 - 4.25E+06 - - - -3.7239 - 1.823 0.469 - 76.4 1 2 0 -0.0104 26 0 0 0 7.52E+07 7.72E+06 - - - 3.4947 0.9999 221125_WJC_METTL3_EV_vs_WT_F06.25155.25155.4 1.17E-09 23/162 K.HAVSDPSILDSLDLNEDER[166.11]EVLINNINR[166.11].R "sp|P05198|IF2A_HUMAN,tr|H0YJS4|H0YJS4_HUMAN,tr|G3V4T5|G3V4T5_HUMAN" 3 3209.6067 0.87 91335 25155 4 3209.608431 803.409 Eukaryotic translation initiation factor 2 subunit 1 OS=Homo sapiens OX=9606 GN=EIF2S1 PE=1 SV=3 4.14 3795.3 - 655817 - - - 0.5272 - 3.276 0.53 - 314.7 1 2 1 0.0017 28 0 0 0 6.92E+07 7.92E+07 - - - 4.2071 1 221125_WJC_METTL3_EV_vs_WT_F06.25156.25156.3 1.18E-11 29/168 K.ALANVNIGSLIC[160.03]NVGAGGPAPAAGAAPAGGPAPSTAAAPAEEK.K sp|P05386|RLA1_HUMAN 1 3807.9214 3.06 91336 25156 3 3807.9266 1270.3144 60S acidic ribosomal protein P1 OS=Homo sapiens OX=9606 GN=RPLP1 PE=1 SV=1 4.53 3795.4 - 923566 - - - 1.369 - 4.767 0.729 - 450.4 1 2 0 0.0052 43 0 0 0 7.02E+06 2.29E+06 - - - 10.2591 1 221125_WJC_METTL3_EV_vs_WT_F06.25158.25158.3 1.74E-09 25/100 K.TRYDSGQDLDEEGMNMGDFDPNNIFK.A "sp|Q99615|DNJC7_HUMAN,tr|A0A6I8PRZ0|A0A6I8PRZ0_HUMAN,tr|A0A6I8PIK4|A0A6I8PIK4_HUMAN,tr|A0A6I8PS32|A0A6I8PS32_HUMAN,tr|A0A6I8PUD4|A0A6I8PUD4_HUMAN,tr|K7ER44|K7ER44_HUMAN,tr|A0A6I8PU73|A0A6I8PU73_HUMAN" 7 3007.26 0.69 91338 25158 3 3007.264213 1003.4273 DnaJ homolog subfamily C member 7 OS=Homo sapiens OX=9606 GN=DNAJC7 PE=1 SV=2 3.85 3795.6 - 575444 - - - 1.3956 - 4.429 0.714 - 477.5 1 2 1 0.0042 26 0 0 0 4.26E+06 6.21E+06 - - - 9.923 1 221125_WJC_METTL3_EV_vs_WT_F06.25159.25159.4 2.94E-05 12/114 K.TLSYLLPAIVHINHQPFLER[166.11].G "sp|P17844|DDX5_HUMAN,tr|A0A7I2V5F5|A0A7I2V5F5_HUMAN,tr|J3QRN5|J3QRN5_HUMAN,tr|A0A7I2V507|A0A7I2V507_HUMAN,tr|J3KTA4|J3KTA4_HUMAN,tr|A0A0G2JLI4|A0A0G2JLI4_HUMAN,tr|A0A7I2V2S0|A0A7I2V2S0_HUMAN,tr|J3QRQ7|J3QRQ7_HUMAN" 8 2370.3088 1.72 91339 25159 4 2370.308885 593.5845 Probable ATP-dependent RNA helicase DDX5 OS=Homo sapiens OX=9606 GN=DDX5 PE=1 SV=1 6.61 3795.8 - 233170 - - - 0.054 - 2.425 0.512 - 61.1 1 2 0 0.0001 20 0 0 0 1.01E+07 5.86E+06 - - - 3.9786 1 221125_WJC_METTL3_EV_vs_WT_F06.25165.25165.3 1.43E-09 22/76 K.HQILEQAVEDYAETVHQLSK[136.11].T "sp|Q01082|SPTB2_HUMAN,tr|A0A087WUZ3|A0A087WUZ3_HUMAN" 2 2345.1743 2.21 91343 25165 3 2345.179919 782.732 "Spectrin beta chain, non-erythrocytic 1 OS=Homo sapiens OX=9606 GN=SPTBN1 PE=1 SV=2" 4.8 3796.6 - 637593 - - - 2.4002 - 4.04 0.621 - 639.4 1 2 0 0.0056 20 0 0 0 9.69E+07 4.39E+07 - - - 8.8493 0.9999 221125_WJC_METTL3_EV_vs_WT_F06.25166.25166.4 1.36E-07 16/114 K.TLSYLLPAIVHINHQPFLER.G "sp|P17844|DDX5_HUMAN,tr|A0A7I2V5F5|A0A7I2V5F5_HUMAN,tr|J3QRN5|J3QRN5_HUMAN,tr|A0A7I2V507|A0A7I2V507_HUMAN,tr|J3KTA4|J3KTA4_HUMAN,tr|A0A0G2JLI4|A0A0G2JLI4_HUMAN,tr|A0A7I2V2S0|A0A7I2V2S0_HUMAN,tr|J3QRQ7|J3QRQ7_HUMAN" 8 2360.3005 1.7 91344 25166 4 2360.309009 591.0824 Probable ATP-dependent RNA helicase DDX5 OS=Homo sapiens OX=9606 GN=DDX5 PE=1 SV=1 6.61 3796.7 - 513106 - - - 3.6106 - 3.022 0.61 - 117.3 1 2 0 0.0085 20 0 0 0 9.96E+06 5.86E+06 - - - 4.9028 1 221125_WJC_METTL3_EV_vs_WT_F06.25169.25169.3 2.16E-09 27/76 K.HQILEQAVEDYAETVHQLSK.T "sp|Q01082|SPTB2_HUMAN,tr|A0A087WUZ3|A0A087WUZ3_HUMAN" 2 2337.1601 2.22 91345 25169 3 2337.17183 780.0606 "Spectrin beta chain, non-erythrocytic 1 OS=Homo sapiens OX=9606 GN=SPTBN1 PE=1 SV=2" 4.8 3797.1 - 1.02E+06 - - - 5.0232 - 5.3 0.6 - 1144 1 2 0 0.0117 20 0 0 0 9.75E+07 4.39E+07 - - - 9.2721 1 221125_WJC_METTL3_EV_vs_WT_F06.25170.25170.4 2.49E-10 25/114 K.HQILEQAVEDYAETVHQLSK.T "sp|Q01082|SPTB2_HUMAN,tr|A0A087WUZ3|A0A087WUZ3_HUMAN" 2 2337.1601 1.86 91346 25170 4 2337.167202 585.2973 "Spectrin beta chain, non-erythrocytic 1 OS=Homo sapiens OX=9606 GN=SPTBN1 PE=1 SV=2" 4.8 3797.2 - 818785 - - - 3.043 - 4.746 0.675 - 762.4 1 2 0 0.0071 20 0 0 0 5.28E+07 2.84E+07 - - - 5.6199 1 221125_WJC_METTL3_EV_vs_WT_F06.25172.25172.4 3.03E-06 20/114 K.HQILEQAVEDYAETVHQLSK[136.11].T "sp|Q01082|SPTB2_HUMAN,tr|A0A087WUZ3|A0A087WUZ3_HUMAN" 2 2345.1743 1.87 91348 25172 4 2345.180071 587.3008 "Spectrin beta chain, non-erythrocytic 1 OS=Homo sapiens OX=9606 GN=SPTBN1 PE=1 SV=2" 4.8 3797.5 - 672097 - - - 2.4651 - 4.043 0.623 - 391.6 1 2 0 0.0058 20 0 0 0 5.37E+07 2.87E+07 - - - 5.114 0.9999 221125_WJC_METTL3_EV_vs_WT_F06.25174.25174.3 2.57E-08 14/56 R.HFYWYLTNEGIQYLR.D "sp|P46783|RS10_HUMAN,tr|A0A2R8Y6L3|A0A2R8Y6L3_HUMAN,tr|F6U211|F6U211_HUMAN,tr|A0A1W2PQS6|A0A1W2PQS6_HUMAN,tr|A0A2R8YFH6|A0A2R8YFH6_HUMAN,tr|A0A2R8Y7H1|A0A2R8Y7H1_HUMAN,tr|S4R435|S4R435_HUMAN" 7 2001.9737 1.12 91350 25174 3 2001.982183 668.3319 40S ribosomal protein S10 OS=Homo sapiens OX=9606 GN=RPS10 PE=1 SV=1 6.75 3797.8 - 438918 - - - 4.2208 - 3.12 0.594 - 337.7 1 2 0 0.0084 15 0 0 0 1.90E+07 1.69E+07 - - - 8.1292 0.9991 221125_WJC_METTL3_EV_vs_WT_F06.25177.25177.3 0.0148 Jul-44 R.LFPPQWIC[160.03]C[160.03]DIR[166.11].Y sp|Q86U44|MTA70_HUMAN 1 1613.7722 0.04 91353 25177 3 1613.77477 538.9313 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 5.82 3798.2 - 236958 - - - 1.5863 - 1.322 0.394 - 53.7 1 2 0 0.0026 12 0 0 0 3.17E+05 8.03E+06 - - - 3.7057 0.9993 221125_WJC_METTL3_EV_vs_WT_F06.25178.25178.3 0.00285 Oct-72 R.GLLQDDAHPTLVTYADHSK[136.11].L "sp|Q86U44|MTA70_HUMAN,tr|F5H6D8|F5H6D8_HUMAN,tr|H0YFV6|H0YFV6_HUMAN,tr|B4DTN4|B4DTN4_HUMAN" 4 2088.0367 0.07 91354 25178 3 2088.033301 697.0195 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 5.13 3798.3 - 188270 - - - -1.6436 - 2.129 0.311 - 111.1 1 2 0 -0.0034 19 0 0 0 7.92E+05 1.13E+07 - - - 3.8629 1 221125_WJC_METTL3_EV_vs_WT_F06.25180.25180.4 3.11E-18 28/156 K.EKKEEQVISLGPQVAEGENVFGVC[160.03]HIF.A "sp|P62263|RS14_HUMAN,tr|A0A2R8Y811|A0A2R8Y811_HUMAN,tr|E5RH77|E5RH77_HUMAN" 3 3042.5121 1.6 91355 25180 4 3042.522402 761.6353 40S ribosomal protein S14 OS=Homo sapiens OX=9606 GN=RPS14 PE=1 SV=3 4.64 3798.5 - 1.84E+06 - - - 3.3952 - 4.601 0.702 - 496.2 1 1 1 0.0103 27 0 0 0 1.24E+08 7.77E+07 - - - 5.8109 0.9999 221125_WJC_METTL3_EV_vs_WT_F06.25183.25183.4 1.00E-06 20/156 K.TFNQVEIKPEMIGHYLGEFSITYKPVK.H "sp|P62841|RS15_HUMAN,tr|K7EM56|K7EM56_HUMAN,tr|A0A0B4J2B4|A0A0B4J2B4_HUMAN,tr|K7ELC2|K7ELC2_HUMAN,tr|S4R417|S4R417_HUMAN" 5 3167.6365 1.34 91357 25183 4 3167.647146 792.9164 40S ribosomal protein S15 OS=Homo sapiens OX=9606 GN=RPS15 PE=1 SV=2 6.43 3798.9 - 1.10E+06 - - - 3.347 - 3.616 0.558 - 151.2 1 2 0 0.0106 27 0 0 0 9.09E+08 6.78E+08 - - - 4.4821 1 221125_WJC_METTL3_EV_vs_WT_F06.25189.25189.4 1.16E-16 27/210 K.QPATVGMAEGNFSGSQPYLQSFPNLAAGSLLVGHHK[136.11].Q sp|Q9HCJ3|RAVR2_HUMAN 1 3717.8453 1.56 91359 25189 4 3717.854575 930.4686 Ribonucleoprotein PTB-binding 2 OS=Homo sapiens OX=9606 GN=RAVER2 PE=1 SV=2 6.92 3799.6 - 865353 - - - 2.4907 - 4.579 0.696 - 337.4 1 2 0 0.0093 36 0 0 0 6.03E+07 3.86E+07 - - - 5.7299 0.9961 221125_WJC_METTL3_EV_vs_WT_F06.25191.25191.4 0.00454 16/174 K.KSEAAVPPWVDTNDEETIQQQILALSADKR.N sp|Q96A49|SYAP1_HUMAN 1 3351.6947 1.33 91361 25191 4 3351.705501 838.9309 Synapse-associated protein 1 OS=Homo sapiens OX=9606 GN=SYAP1 PE=1 SV=1 4.3 3799.8 - 2.33E+06 - - - 3.2333 - 1.819 0.301 - 84.5 1 2 0 0.0108 30 0 0 0 4.37E+09 3.27E+09 - - - 2.026 1 221125_WJC_METTL3_EV_vs_WT_F06.25198.25198.4 4.18E-10 25/174 K.K[136.11]SEAAVPPWVDTNDEETIQQQILALSADK[136.11]R[166.11].N sp|Q96A49|SYAP1_HUMAN 1 3377.7313 1.33 91366 25198 4 3377.736167 845.4401 Synapse-associated protein 1 OS=Homo sapiens OX=9606 GN=SYAP1 PE=1 SV=1 4.3 3800.8 - 2.85E+06 - - - 1.4308 - 3.109 0.607 - 236.4 1 2 0 0.0048 30 0 0 0 4.34E+09 3.25E+09 - - - 4.8551 1 221125_WJC_METTL3_EV_vs_WT_F06.25203.25203.3 3.93E-12 24/104 K.TFNQVEIKPEMIGHYLGEFSITYKPVK.H "sp|P62841|RS15_HUMAN,tr|K7EM56|K7EM56_HUMAN,tr|A0A0B4J2B4|A0A0B4J2B4_HUMAN,tr|K7ELC2|K7ELC2_HUMAN,tr|S4R417|S4R417_HUMAN" 5 3167.6365 1.34 91368 25203 3 3167.64632 1056.8861 40S ribosomal protein S15 OS=Homo sapiens OX=9606 GN=RPS15 PE=1 SV=2 6.43 3801.5 - 1.01E+06 - - - 3.0862 - 4.758 0.687 - 511.9 1 2 0 0.0098 27 0 0 0 4.09E+08 3.06E+08 - - - 9.7853 1 221125_WJC_METTL3_EV_vs_WT_F06.25204.25204.4 1.17E-13 28/186 K.PSHSVDAHTAEVNC[160.03]LSFNPYSEFILATGSADK.T "sp|Q09028|RBBP4_HUMAN,tr|H0YCT5|H0YCT5_HUMAN,tr|H0YDK2|H0YDK2_HUMAN,tr|H0YEU5|H0YEU5_HUMAN,tr|H0YF10|H0YF10_HUMAN" 5 3463.599 1.27 91369 25204 4 3463.60196 866.907 Histone-binding protein RBBP4 OS=Homo sapiens OX=9606 GN=RBBP4 PE=1 SV=3 4.72 3801.6 - 893912 - - - 0.8402 - 4.626 0.706 - 451.5 1 1 0 0.0029 32 0 0 0 1.35E+07 1.06E+07 - - - 5.8327 0.9999 221125_WJC_METTL3_EV_vs_WT_F06.25206.25206.4 0.000249 12/198 R.SHLNFSMLESPALHC[160.03]QPSTSSAFPIGSSGFSLVK.E sp|P49790|NU153_HUMAN 1 3619.7439 3 91371 25206 4 3619.750317 905.9433 Nuclear pore complex protein Nup153 OS=Homo sapiens OX=9606 GN=NUP153 PE=1 SV=2 6.66 3801.8 - 367213 - - - 1.7617 - 2.422 0.475 - 49.1 1 2 0 0.0064 34 0 0 0 7.38E+06 2.46E+06 - - - 3.6224 1 221125_WJC_METTL3_EV_vs_WT_F06.25207.25207.3 5.11E-06 17/56 K.VSQEILELLNTTTAK[136.11].E "sp|Q86U44|MTA70_HUMAN,tr|H0YFV6|H0YFV6_HUMAN" 2 1666.9233 0.02 91372 25207 3 1666.922523 556.6484 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 4.53 3801.9 - 276179 - - - -0.4463 - 3.176 0.493 - 480.7 1 2 0 -0.0007 15 0 0 0 1.56E+07 6.52E+08 - - - 7.0517 1 221125_WJC_METTL3_EV_vs_WT_F06.25212.25212.4 1.26E-13 19/186 K.PSHSVDAHTAEVNC[160.03]LSFNPYSEFILATGSADK[136.11].T "sp|Q09028|RBBP4_HUMAN,tr|H0YCT5|H0YCT5_HUMAN,tr|H0YDK2|H0YDK2_HUMAN,tr|H0YEU5|H0YEU5_HUMAN,tr|H0YF10|H0YF10_HUMAN" 5 3471.6132 1.31 91375 25212 4 3472.61424 868.9106 Histone-binding protein RBBP4 OS=Homo sapiens OX=9606 GN=RBBP4 PE=1 SV=3 4.72 3802.6 - 464555 - - - 288.3357 - 3.7 0.686 - 200.4 1 1 0 1.001 32 0 0 0 1.39E+07 1.06E+07 - - - 5.3147 1 221125_WJC_METTL3_EV_vs_WT_F06.25216.25216.3 1.61E-07 15/68 K.YVHYEIDAC[160.03]MDSEAPGSK[136.11].D "sp|Q86U44|MTA70_HUMAN,tr|H0YFV6|H0YFV6_HUMAN" 2 2078.8805 0.01 91377 25216 3 2078.881394 693.9674 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 4.31 3803.1 - 623836 - - - 0.4339 - 3.166 0.665 - 229.4 1 2 0 0.0009 18 0 0 0 5.80E+05 5.00E+07 - - - 8.8236 1 221125_WJC_METTL3_EV_vs_WT_F06.25218.25218.3 1.15E-08 28/104 K.TFNQVEIK[136.11]PEMIGHYLGEFSITYK[136.11]PVK[136.11].H "sp|P62841|RS15_HUMAN,tr|K7EM56|K7EM56_HUMAN,tr|A0A0B4J2B4|A0A0B4J2B4_HUMAN,tr|K7ELC2|K7ELC2_HUMAN,tr|S4R417|S4R417_HUMAN" 5 3191.6791 1.34 91378 25218 3 3191.695935 1064.9003 40S ribosomal protein S15 OS=Homo sapiens OX=9606 GN=RPS15 PE=1 SV=2 6.43 3803.4 - 303455 - - - 5.2609 - 5.059 0.705 - 722.4 1 2 0 0.0168 27 0 0 0 4.09E+08 3.06E+08 - - - 10.1251 1 221125_WJC_METTL3_EV_vs_WT_F06.25222.25222.3 3.08E-07 20/116 K.KSEAAVPPWVDTNDEETIQQQILALSADKR.N sp|Q96A49|SYAP1_HUMAN 1 3351.6947 1.51 91380 25222 3 3351.700749 1118.2388 Synapse-associated protein 1 OS=Homo sapiens OX=9606 GN=SYAP1 PE=1 SV=1 4.3 3803.8 - 828932 - - - 1.8155 - 3.402 0.657 - 236.7 1 2 0 0.0061 30 0 0 0 2.35E+08 1.56E+08 - - - 8.68 1 221125_WJC_METTL3_EV_vs_WT_F06.25223.25223.3 1.42E-09 16/116 K.K[136.11]SEAAVPPWVDTNDEETIQQQILALSADK[136.11]R[166.11].N sp|Q96A49|SYAP1_HUMAN 1 3377.7313 1.48 91381 25223 3 3377.732213 1126.9177 Synapse-associated protein 1 OS=Homo sapiens OX=9606 GN=SYAP1 PE=1 SV=1 4.3 3803.9 - 642380 - - - 0.2602 - 2.694 0.624 - 170.9 1 2 0 0.0009 30 0 0 0 2.35E+08 1.59E+08 - - - 7.7767 1 221125_WJC_METTL3_EV_vs_WT_F06.25232.25232.4 1.07E-13 27/210 R.AHESAVTGLSLHATGDYLLSSSDDQYWAFSDIQTGR[166.11].V sp|Q9UMS4|PRP19_HUMAN 1 3907.8165 1.83 91385 25232 4 3907.815622 977.9614 Pre-mRNA-processing factor 19 OS=Homo sapiens OX=9606 GN=PRPF19 PE=1 SV=1 4.34 3805 - 2.59E+06 - - - -0.2147 - 4.601 0.691 - 403.1 1 2 0 -0.0008 36 0 0 0 1.70E+08 9.25E+07 - - - 5.6901 1 221125_WJC_METTL3_EV_vs_WT_F06.25238.25238.4 1.27E-14 42/210 R.AHESAVTGLSLHATGDYLLSSSDDQYWAFSDIQTGR.V sp|Q9UMS4|PRP19_HUMAN 1 3897.8082 1.83 91389 25238 4 3897.805111 975.4593 Pre-mRNA-processing factor 19 OS=Homo sapiens OX=9606 GN=PRPF19 PE=1 SV=1 4.34 3805.9 - 2.97E+06 - - - -0.7902 - 6.349 0.7 - 1019.9 1 2 0 -0.0031 36 0 0 0 1.72E+08 9.37E+07 - - - 5.8628 0.994 221125_WJC_METTL3_EV_vs_WT_F06.25239.25239.3 3.64E-07 14/76 W.ITLGNQLDGIHLLDPDVVAR[166.11].F sp|Q86U44|MTA70_HUMAN 1 2168.1829 0 91390 25239 3 2168.177436 723.7349 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 4.41 3806 - 877820 - - - -2.5141 - 2.879 0.523 - 142.5 1 1 0 -0.0055 20 0 0 0 3.73E+04 2.86E+07 - - - 6.9348 1 221125_WJC_METTL3_EV_vs_WT_F06.25245.25245.2 1.47E-15 21/52 K.TFNQVEIKPEMIGHYLGEFSITYKPVK.H "sp|P62841|RS15_HUMAN,tr|K7EM56|K7EM56_HUMAN,tr|A0A0B4J2B4|A0A0B4J2B4_HUMAN,tr|K7ELC2|K7ELC2_HUMAN,tr|S4R417|S4R417_HUMAN" 5 3167.6365 2.02 91393 25245 2 3169.645447 1584.8255 40S ribosomal protein S15 OS=Homo sapiens OX=9606 GN=RPS15 PE=1 SV=2 6.43 3806.8 - 0 - - - 634.1962 - 3.913 0.712 - 518.7 1 2 0 2.0089 27 0 0 0 6.01E+07 2.97E+07 - - - 7.0232 1 221125_WJC_METTL3_EV_vs_WT_F06.25251.25251.4 4.62E-15 28/156 K.TFNQVEIK[136.11]PEMIGHYLGEFSITYK[136.11]PVK[136.11].H "sp|P62841|RS15_HUMAN,tr|K7EM56|K7EM56_HUMAN,tr|A0A0B4J2B4|A0A0B4J2B4_HUMAN,tr|K7ELC2|K7ELC2_HUMAN,tr|S4R417|S4R417_HUMAN" 5 3191.6791 1.33 91395 25251 4 3191.675656 798.9271 40S ribosomal protein S15 OS=Homo sapiens OX=9606 GN=RPS15 PE=1 SV=2 6.43 3807.6 - 8.49E+06 - - - -1.0928 - 3.756 0.707 - 244.7 1 2 0 -0.0035 27 0 0 0 9.00E+08 6.75E+08 - - - 5.7928 1 221125_WJC_METTL3_EV_vs_WT_F06.25255.25255.2 6.95E-16 20/52 K.TFNQVEIK[136.11]PEMIGHYLGEFSITYK[136.11]PVK[136.11].H "sp|P62841|RS15_HUMAN,tr|K7EM56|K7EM56_HUMAN,tr|A0A0B4J2B4|A0A0B4J2B4_HUMAN,tr|K7ELC2|K7ELC2_HUMAN,tr|S4R417|S4R417_HUMAN" 5 3191.6791 2.02 91397 25255 2 3191.671981 1596.8468 40S ribosomal protein S15 OS=Homo sapiens OX=9606 GN=RPS15 PE=1 SV=2 6.43 3808.1 - 0 - - - -2.2443 - 3.953 0.757 - 446 1 2 0 -0.0072 27 0 0 0 6.01E+07 2.97E+07 - - - 8.0092 1 221125_WJC_METTL3_EV_vs_WT_F06.25262.25262.3 1.14E-12 31/132 K.DHTPSQELALTQSVGGDSSADR[166.11]LFPPQWIC[160.03]C[160.03]DIR[166.11].Y sp|Q86U44|MTA70_HUMAN 1 3875.811 0.001 91401 25262 3 3875.79929 1292.9443 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 4.35 3809 - 3.32E+06 - - - -3.0244 - 4.065 0.665 - 429 1 2 1 -0.0117 34 0 0 0 0.00E+00 1.01E+08 - - - 9.1773 1 221125_WJC_METTL3_EV_vs_WT_F06.25268.25268.4 5.33E-14 34/162 R.VAIEHLDKISDSVLVDIKDTEPLIQTAK.T "sp|P48643|TCPE_HUMAN,tr|E9PCA1|E9PCA1_HUMAN,tr|B7ZAR1|B7ZAR1_HUMAN,tr|E7ENZ3|E7ENZ3_HUMAN" 4 3089.686 0.69 91404 25268 4 3089.685987 773.4288 T-complex protein 1 subunit epsilon OS=Homo sapiens OX=9606 GN=CCT5 PE=1 SV=1 4.52 3809.7 - 424920 - - - -0.0032 - 6.084 0.674 - 175.4 1 2 2 0 28 0 0 0 1.70E+08 2.47E+08 - - - 5.6531 0.9999 221125_WJC_METTL3_EV_vs_WT_F06.25269.25269.4 0.000307 16/132 K.VFNTTPDDLDLHVIYDVSHNIAK.V sp|Q9Y3I0|RTCB_HUMAN 1 2625.3075 1.96 91405 25269 4 2625.301929 657.3341 RNA-splicing ligase RtcB homolog OS=Homo sapiens OX=9606 GN=RTCB PE=1 SV=1 4.54 3809.8 - 746188 - - - -2.1152 - 2.982 0.457 - 114.3 1 2 0 -0.0056 23 0 0 0 1.57E+07 8.02E+06 - - - 3.5562 0.9999 221125_WJC_METTL3_EV_vs_WT_F06.25276.25276.4 1.07E-11 34/162 R.VAIEHLDK[136.11]ISDSVLVDIK[136.11]DTEPLIQTAK[136.11].T "sp|P48643|TCPE_HUMAN,tr|E9PCA1|E9PCA1_HUMAN,tr|B7ZAR1|B7ZAR1_HUMAN,tr|E7ENZ3|E7ENZ3_HUMAN" 4 3113.7286 0.69 91408 25276 4 3113.723525 779.4394 T-complex protein 1 subunit epsilon OS=Homo sapiens OX=9606 GN=CCT5 PE=1 SV=1 4.52 3810.7 - 7.11E+06 - - - -1.6289 - 5.156 0.581 - 670.5 1 2 2 -0.0051 28 0 0 0 1.70E+08 2.47E+08 - - - 4.7909 1 221125_WJC_METTL3_EV_vs_WT_F06.25283.25283.3 3.51E-08 21/72 R.NKLNDLEEALQQAKEDLAR.L sp|P35908|K22E_HUMAN 1 2197.1339 999 91410 25283 3 2197.131937 733.3852 "Keratin, type II cytoskeletal 2 epidermal OS=Homo sapiens OX=9606 GN=KRT2 PE=1 SV=2" 4.51 3811.8 - 487291 - - - -0.8821 - 4.534 0.61 - 695.9 1 2 2 -0.0019 19 0 0 0 1.34E+09 0.00E+00 - - - 9.0541 1 221125_WJC_METTL3_EV_vs_WT_F06.25288.25288.3 4.23E-12 19/120 K.INSSPNVNTTASGVEDLNIIQVTIPDDDNER.L "sp|P78347|GTF2I_HUMAN,tr|A0A494C1K3|A0A494C1K3_HUMAN" 2 3339.6066 1.97 91412 25288 3 3339.597111 1114.2095 General transcription factor II-I OS=Homo sapiens OX=9606 GN=GTF2I PE=1 SV=2 3.66 3812.5 - 691239 - - - -2.8524 - 3.327 0.663 - 154.4 1 2 0 -0.0095 31 0 0 0 4.69E+08 2.38E+08 - - - 8.6947 0.9999 221125_WJC_METTL3_EV_vs_WT_F06.25294.25294.4 4.13E-05 21/108 R.NKLNDLEEALQQAKEDLAR.L sp|P35908|K22E_HUMAN 1 2197.1339 1714.75 91416 25294 4 2197.1329 550.2907 "Keratin, type II cytoskeletal 2 epidermal OS=Homo sapiens OX=9606 GN=KRT2 PE=1 SV=2" 4.51 3813.2 - 2.24E+06 - - - -0.4438 - 3.552 0.483 - 306.1 1 2 2 -0.001 19 0 0 0 4.82E+08 2.81E+05 - - - 3.8585 1 221125_WJC_METTL3_EV_vs_WT_F06.25297.25297.4 4.30E-15 28/132 R.HVQETTDSILSHFQSLSYSLAER.S "sp|Q9UPN3|MACF1_HUMAN,tr|H3BQK9|H3BQK9_HUMAN,tr|A0A7P0MQR8|A0A7P0MQR8_HUMAN,tr|H0Y390|H0Y390_HUMAN,tr|H3BPE1|H3BPE1_HUMAN,tr|A0A590UJG2|A0A590UJG2_HUMAN" 6 2647.2878 2.26 91419 25297 4 2647.284728 662.8292 "Microtubule-actin cross-linking factor 1, isoforms 1\2\3\5 OS=Homo sapiens OX=9606 GN=MACF1 PE=1 SV=4" 5.27 3813.6 - 794002 - - - -1.1638 - 4.576 0.675 - 619.6 1 2 0 -0.0031 23 0 0 0 2.64E+07 1.17E+07 - - - 5.5931 1 221125_WJC_METTL3_EV_vs_WT_F06.25302.25302.4 1.37E-10 20/144 R.HPVEELLDSYHNQVELALQIENQHR.A sp|O00443|P3C2A_HUMAN 1 3010.4897 1.66 91421 25302 4 3010.488088 753.6297 Phosphatidylinositol 4-phosphate 3-kinase C2 domain-containing subunit alpha OS=Homo sapiens OX=9606 GN=PIK3C2A PE=1 SV=2 4.89 3814.2 - 1.57E+06 - - - -0.5345 - 3.841 0.59 - 259.5 1 2 0 -0.0016 25 0 0 0 3.72E+07 2.24E+07 - - - 4.789 1 221125_WJC_METTL3_EV_vs_WT_F06.25303.25303.4 1.74E-08 18/144 R.HPVEELLDSYHNQVELALQIENQHR[166.11].A sp|O00443|P3C2A_HUMAN 1 3020.498 1.71 91422 25303 4 3020.505875 756.1318 Phosphatidylinositol 4-phosphate 3-kinase C2 domain-containing subunit alpha OS=Homo sapiens OX=9606 GN=PIK3C2A PE=1 SV=2 4.89 3814.4 - 715595 - - - 2.6181 - 3.124 0.557 - 196 1 2 0 0.0079 25 0 0 0 3.73E+07 2.18E+07 - - - 4.4343 1 221125_WJC_METTL3_EV_vs_WT_F06.25304.25304.3 1.31E-13 25/108 R.VAIEHLDKISDSVLVDIKDTEPLIQTAK.T "sp|P48643|TCPE_HUMAN,tr|E9PCA1|E9PCA1_HUMAN,tr|B7ZAR1|B7ZAR1_HUMAN,tr|E7ENZ3|E7ENZ3_HUMAN" 4 3089.686 0.73 91423 25304 3 3089.682061 1030.9026 T-complex protein 1 subunit epsilon OS=Homo sapiens OX=9606 GN=CCT5 PE=1 SV=1 4.52 3814.5 - 1.15E+06 - - - -1.2739 - 4.961 0.632 - 520.5 1 2 2 -0.0039 28 0 0 0 1.35E+07 1.86E+07 - - - 9.2698 1 221125_WJC_METTL3_EV_vs_WT_F06.25308.25308.4 4.89E-14 25/252 K.DLTVC[160.03]EPPKPQC[160.03]SLPQDPAIVQSSLGSSTSSFQSMGSYGPFGR.M "sp|Q8ND56|LS14A_HUMAN,tr|A0A140TA76|A0A140TA76_HUMAN,tr|K7EMZ9|K7EMZ9_HUMAN" 3 4599.1356 0.94 91425 25308 4 4599.131777 1150.7912 Protein LSM14 homolog A OS=Homo sapiens OX=9606 GN=LSM14A PE=1 SV=3 4.56 3815 - 1.27E+06 - - - -0.8345 - 4.558 0.72 - 215.7 1 2 0 -0.0038 43 0 0 0 8.55E+08 9.12E+08 - - - 5.9235 1 221125_WJC_METTL3_EV_vs_WT_F06.25310.25310.4 8.92E-07 17/108 R.LNEQYEHASIHLWDLLEGK[136.11].E "sp|Q14444|CAPR1_HUMAN,tr|G3V153|G3V153_HUMAN" 2 2302.1473 1.1 91427 25310 4 2302.147199 576.5441 Caprin-1 OS=Homo sapiens OX=9606 GN=CAPRIN1 PE=1 SV=2 4.8 3815.3 - 770838 - - - -0.0643 - 2.612 0.499 - 193 1 2 0 -0.0001 19 0 0 0 2.62E+07 2.39E+07 - - - 3.894 1 221125_WJC_METTL3_EV_vs_WT_F06.25315.25315.4 5.74E-06 12/108 R.GLLQDDAHPTLVTYADHSK[136.11].L "sp|Q86U44|MTA70_HUMAN,tr|F5H6D8|F5H6D8_HUMAN,tr|H0YFV6|H0YFV6_HUMAN,tr|B4DTN4|B4DTN4_HUMAN" 4 2088.0367 0.01 91429 25315 4 2088.035839 523.0165 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 5.13 3816 - 721754 - - - -0.4282 - 2.727 0.541 - 100.7 1 2 0 -0.0009 19 0 0 0 1.44E+05 1.66E+07 - - - 4.274 1 221125_WJC_METTL3_EV_vs_WT_F06.25320.25320.3 7.26E-15 35/108 R.VAIEHLDK[136.11]ISDSVLVDIK[136.11]DTEPLIQTAK[136.11].T "sp|P48643|TCPE_HUMAN,tr|E9PCA1|E9PCA1_HUMAN,tr|B7ZAR1|B7ZAR1_HUMAN,tr|E7ENZ3|E7ENZ3_HUMAN" 4 3113.7286 0.73 91433 25320 3 3113.726588 1038.9168 T-complex protein 1 subunit epsilon OS=Homo sapiens OX=9606 GN=CCT5 PE=1 SV=1 4.52 3816.6 - 1.67E+06 - - - -0.6452 - 5.816 0.711 - 1111.9 1 2 2 -0.002 28 0 0 0 1.35E+07 1.86E+07 - - - 10.5169 0.9996 221125_WJC_METTL3_EV_vs_WT_F06.25321.25321.4 3.16E-05 23/180 K.INSSPNVNTTASGVEDLNIIQVTIPDDDNER.L "sp|P78347|GTF2I_HUMAN,tr|A0A494C1K3|A0A494C1K3_HUMAN" 2 3339.6066 6.35 91434 25321 4 3339.591941 835.9089 General transcription factor II-I OS=Homo sapiens OX=9606 GN=GTF2I PE=1 SV=2 3.66 3816.7 - 1.35E+06 - - - -4.4005 - 3.691 0.473 - 153.2 1 2 0 -0.0147 31 0 0 0 5.48E+07 8.63E+06 - - - 3.7358 1 221125_WJC_METTL3_EV_vs_WT_F06.25322.25322.3 3.41E-12 28/88 R.HVQETTDSILSHFQSLSYSLAER.S "sp|Q9UPN3|MACF1_HUMAN,tr|H3BQK9|H3BQK9_HUMAN,tr|A0A7P0MQR8|A0A7P0MQR8_HUMAN,tr|H0Y390|H0Y390_HUMAN,tr|H3BPE1|H3BPE1_HUMAN,tr|A0A590UJG2|A0A590UJG2_HUMAN" 6 2647.2878 8.18 91435 25322 3 2647.280716 883.4365 "Microtubule-actin cross-linking factor 1, isoforms 1\2\3\5 OS=Homo sapiens OX=9606 GN=MACF1 PE=1 SV=4" 5.27 3816.9 - 1.18E+06 - - - -2.6793 - 5.536 0.658 - 656.7 1 2 0 -0.0071 23 0 0 0 1.46E+07 1.78E+06 - - - 9.8886 1 221125_WJC_METTL3_EV_vs_WT_F06.25323.25323.4 1.45E-11 19/120 K.NPDDPDTVDVIMHMLDRDHDR.R sp|Q5D862|FILA2_HUMAN 1 2505.1013 999 91436 25323 4 2505.106833 627.2826 Filaggrin-2 OS=Homo sapiens OX=9606 GN=FLG2 PE=1 SV=1 4.21 3817 - 801344 - - - 2.2203 - 3.599 0.662 - 270.2 1 2 1 0.0056 21 0 0 0 1.15E+07 0.00E+00 - - - 5.4099 0.996 221125_WJC_METTL3_EV_vs_WT_F06.25331.25331.3 3.76E-06 18/76 K.HAASDVDLEIESLLNQQSTK[136.11].E "sp|Q86U44|MTA70_HUMAN,tr|F5H6D8|F5H6D8_HUMAN,tr|H0YFV6|H0YFV6_HUMAN,tr|B4DTN4|B4DTN4_HUMAN" 4 2205.1005 0.01 91439 25331 3 2206.093593 736.0408 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 4.31 3818.1 - 1.55E+06 - - - 450.3817 - 3.721 0.589 - 408.7 1 2 0 0.9931 20 0 0 0 2.17E+06 2.24E+08 - - - 8.0194 1 221125_WJC_METTL3_EV_vs_WT_F06.25332.25332.2 2.83E-10 22/36 R.NKLNDLEEALQQAKEDLAR.L sp|P35908|K22E_HUMAN 1 2197.1339 1.7 91440 25332 2 2197.137348 1099.5742 "Keratin, type II cytoskeletal 2 epidermal OS=Homo sapiens OX=9606 GN=KRT2 PE=1 SV=2" 4.51 3818.2 - 0 - - - 1.5807 - 4.764 0.685 - 862.7 1 2 2 0.0035 19 0 0 0 8.14E+06 4.79E+06 - - - 7.9373 1 221125_WJC_METTL3_EV_vs_WT_F06.25343.25343.3 0.0172 23/64 K.LNDLEDALQQAKEDLAR.L sp|P04264|K2C1_HUMAN 1 1940.9803 13.3 91447 25343 3 1940.983733 648.0007 "Keratin, type II cytoskeletal 1 OS=Homo sapiens OX=9606 GN=KRT1 PE=1 SV=6" 4.11 3819.6 - 1.00E+06 - - - 1.7512 - 4.588 0.589 - 932.6 1 2 1 0.0034 17 0 0 0 1.45E+07 1.09E+06 - - - 8.9545 1 221125_WJC_METTL3_EV_vs_WT_F06.25348.25348.3 2.49E-13 21/168 K.DLTVC[160.03]EPPKPQC[160.03]SLPQDPAIVQSSLGSSTSSFQSMGSYGPFGR.M "sp|Q8ND56|LS14A_HUMAN,tr|A0A140TA76|A0A140TA76_HUMAN,tr|K7EMZ9|K7EMZ9_HUMAN" 3 4599.1356 1.36 91450 25348 3 4599.133691 1534.0525 Protein LSM14 homolog A OS=Homo sapiens OX=9606 GN=LSM14A PE=1 SV=3 4.56 3820.3 - 810198 - - - -0.4183 - 4.585 0.738 - 214.3 1 2 0 -0.0019 43 0 0 0 4.27E+07 3.14E+07 - - - 10.2708 1 221125_WJC_METTL3_EV_vs_WT_F06.25350.25350.3 1.73E-10 39/180 K.GSLGGGFSSGGFSGGSFSRGSSGGGC[160.03]FGGSSGGYGGLGGFGGGSFR.G "sp|P13645|K1C10_HUMAN,tr|A0A1B0GVI3|A0A1B0GVI3_HUMAN" 2 4030.7314 -1 91451 25350 3 4031.712203 1344.5844 "Keratin, type I cytoskeletal 10 OS=Homo sapiens OX=9606 GN=KRT10 PE=1 SV=6" 9.5 3820.5 - 3.85E+06 - - - 243.3427 - 5.557 0.738 - 625.8 1 2 1 0.9808 46 0 0 0 0.00E+00 0.00E+00 - - - 10.442 1 221125_WJC_METTL3_EV_vs_WT_F06.25353.25353.2 3.60E-13 23/60 K.INSSPNVNTTASGVEDLNIIQVTIPDDDNER.L "sp|P78347|GTF2I_HUMAN,tr|A0A494C1K3|A0A494C1K3_HUMAN" 2 3339.6066 2.35 91454 25353 2 3341.625447 1670.8106 General transcription factor II-I OS=Homo sapiens OX=9606 GN=GTF2I PE=1 SV=2 3.66 3820.9 - 1.34E+06 - - - 604.5053 - 3.974 0.719 - 399.6 1 2 0 2.0188 31 0 0 0 1.61E+07 6.86E+06 - - - 7.1099 1 221125_WJC_METTL3_EV_vs_WT_F06.25356.25356.4 1.22E-13 32/252 K.DLTVC[160.03]EPPK[136.11]PQC[160.03]SLPQDPAIVQSSLGSSTSSFQSMGSYGPFGR[166.11].M "sp|Q8ND56|LS14A_HUMAN,tr|A0A140TA76|A0A140TA76_HUMAN,tr|K7EMZ9|K7EMZ9_HUMAN" 3 4617.1581 0.94 91455 25356 4 4617.154512 1155.2968 Protein LSM14 homolog A OS=Homo sapiens OX=9606 GN=LSM14A PE=1 SV=3 4.56 3821.3 - 1.71E+07 - - - -0.7739 - 4.925 0.701 - 329.6 1 2 0 -0.0036 43 0 0 0 8.57E+08 9.12E+08 - - - 5.7803 1 221125_WJC_METTL3_EV_vs_WT_F06.25358.25358.4 1.24E-15 42/198 R.LGQHVPTLHPTSEELTIAGMTFTTFDLGGHEQAR[166.11].R "sp|Q9NR31|SAR1A_HUMAN,tr|Q5SQT8|Q5SQT8_HUMAN" 2 3700.8183 1.19 91457 25358 4 3700.81551 926.2119 GTP-binding protein SAR1a OS=Homo sapiens OX=9606 GN=SAR1A PE=1 SV=1 5.26 3821.6 - 2.11E+06 - - - -0.7579 - 6.047 0.663 - 1144.6 1 2 0 -0.0028 34 0 0 0 4.08E+08 3.42E+08 - - - 5.5326 1 221125_WJC_METTL3_EV_vs_WT_F06.25360.25360.4 8.93E-06 21/114 R.K[136.11]YDFDSSEVLQGLDFFGNK[136.11]K[136.11].S "sp|Q9Y2R4|DDX52_HUMAN,tr|A0A087X069|A0A087X069_HUMAN,tr|A0A087WTD6|A0A087WTD6_HUMAN,tr|A0A087X1P7|A0A087X1P7_HUMAN" 4 2360.1751 0.95 91459 25360 4 2360.177191 591.051 Probable ATP-dependent RNA helicase DDX52 OS=Homo sapiens OX=9606 GN=DDX52 PE=1 SV=3 4.68 3821.9 - 1.20E+06 - - - 0.8953 - 3.357 0.531 - 353.3 1 2 0 0.0021 20 0 0 0 2.04E+07 2.16E+07 - - - 4.2521 1 221125_WJC_METTL3_EV_vs_WT_F06.25361.25361.2 1.06E-12 20/60 K.INSSPNVNTTASGVEDLNIIQVTIPDDDNER[166.11].L "sp|P78347|GTF2I_HUMAN,tr|A0A494C1K3|A0A494C1K3_HUMAN" 2 3349.6149 2.35 91460 25361 2 3349.611305 1675.8147 General transcription factor II-I OS=Homo sapiens OX=9606 GN=GTF2I PE=1 SV=2 3.66 3822 - 747791 - - - -1.0753 - 3.625 0.729 - 367 1 2 0 -0.0036 31 0 0 0 1.61E+07 6.86E+06 - - - 7.5905 1 221125_WJC_METTL3_EV_vs_WT_F06.25369.25369.4 8.66E-16 42/198 R.LGQHVPTLHPTSEELTIAGMTFTTFDLGGHEQAR.R "sp|Q9NR31|SAR1A_HUMAN,tr|Q5SQT8|Q5SQT8_HUMAN" 2 3690.81 1.19 91464 25369 4 3690.810012 923.7098 GTP-binding protein SAR1a OS=Homo sapiens OX=9606 GN=SAR1A PE=1 SV=1 5.26 3823 - 4.92E+06 - - - -0.0089 - 6.419 0.683 - 1256.9 1 2 0 0 34 0 0 0 4.09E+08 3.45E+08 - - - 5.7253 1 221125_WJC_METTL3_EV_vs_WT_F06.25370.25370.4 3.66E-07 51/240 R.LASLMNLGMSSSLNQQGAHSALSSASTSSHNLQSIFNIGSR.G "sp|P43243|MATR3_HUMAN,tr|A8MXP9|A8MXP9_HUMAN,tr|D6R991|D6R991_HUMAN,tr|D6REK4|D6REK4_HUMAN,tr|A0A0R4J2E8|A0A0R4J2E8_HUMAN,tr|D6RCM3|D6RCM3_HUMAN,tr|D6R8Z5|D6R8Z5_HUMAN,tr|D6REM6|D6REM6_HUMAN" 8 4203.0437 1.71 91465 25370 4 4203.04105 1051.7682 Matrin-3 OS=Homo sapiens OX=9606 GN=MATR3 PE=1 SV=2 9.76 3823.1 - 8.26E+06 - - - -0.6314 - 6.861 0.626 - 1087.7 1 2 0 -0.0027 41 0 0 0 3.43E+09 2.00E+09 - - - 5.2272 1 221125_WJC_METTL3_EV_vs_WT_F06.25374.25374.3 2.01E-12 30/168 K.DLTVC[160.03]EPPK[136.11]PQC[160.03]SLPQDPAIVQSSLGSSTSSFQSMGSYGPFGR[166.11].M "sp|Q8ND56|LS14A_HUMAN,tr|A0A140TA76|A0A140TA76_HUMAN,tr|K7EMZ9|K7EMZ9_HUMAN" 3 4617.1581 1.36 91467 25374 3 4617.154908 1540.06 Protein LSM14 homolog A OS=Homo sapiens OX=9606 GN=LSM14A PE=1 SV=3 4.56 3823.6 - 1.68E+06 - - - -0.6881 - 4.99 0.757 - 566.1 1 2 0 -0.0032 43 0 0 0 4.27E+07 3.14E+07 - - - 10.677 0.9998 221125_WJC_METTL3_EV_vs_WT_F06.25381.25381.3 9.51E-06 Nov-52 K.GAVHDVKDVLDSVL.- sp|P81605|DCD_HUMAN 1 1465.7777 29.38 91470 25381 3 1465.776637 489.5998 Dermcidin OS=Homo sapiens OX=9606 GN=DCD PE=1 SV=2 4.41 3824.5 - 827083 - - - -0.6972 - 2.001 0.521 - 112.7 1 2 1 -0.001 14 0 0 0 1.10E+07 3.74E+05 - - - 6.1917 0.9999 221125_WJC_METTL3_EV_vs_WT_F06.25382.25382.4 2.42E-06 16/102 R.DGFIDK[136.11]EDLHDMLASLGK[136.11].N "sp|O14950|ML12B_HUMAN,sp|P19105|ML12A_HUMAN,sp|P24844|MYL9_HUMAN,tr|J3KTJ1|J3KTJ1_HUMAN,tr|J3QRS3|J3QRS3_HUMAN" 5 2018.9954 1.43 91471 25382 4 2018.99308 505.7561 Myosin regulatory light chain 12B OS=Homo sapiens OX=9606 GN=MYL12B PE=1 SV=2 4.35 3824.7 - 629280 - - - -1.1451 - 2.551 0.523 - 183.6 1 2 1 -0.0023 18 0 0 0 6.41E+06 4.48E+06 - - - 4.0984 0.9798 221125_WJC_METTL3_EV_vs_WT_F06.25384.25384.3 4.57E-05 19/108 D.STTVAAFASSLVSGLNSSASEPAK[136.11]EPAK[136.11].K "sp|Q86U44|MTA70_HUMAN,tr|F5H6D8|F5H6D8_HUMAN,tr|H0YFV6|H0YFV6_HUMAN,tr|B4DTN4|B4DTN4_HUMAN" 4 2722.3996 0.001 91473 25384 3 2722.392585 908.4738 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 5.86 3824.9 - 1.33E+06 - - - -2.5786 - 3.672 0.531 - 276.6 1 1 1 -0.007 28 0 0 0 0.00E+00 8.94E+06 - - - 7.4507 1 221125_WJC_METTL3_EV_vs_WT_F06.25387.25387.3 5.98E-12 36/160 R.LASLMNLGMSSSLNQQGAHSALSSASTSSHNLQSIFNIGSR[166.11].G "sp|P43243|MATR3_HUMAN,tr|A8MXP9|A8MXP9_HUMAN,tr|D6R991|D6R991_HUMAN,tr|D6REK4|D6REK4_HUMAN,tr|A0A0R4J2E8|A0A0R4J2E8_HUMAN,tr|D6RCM3|D6RCM3_HUMAN,tr|D6R8Z5|D6R8Z5_HUMAN,tr|D6REM6|D6REM6_HUMAN" 8 4213.052 2.01 91474 25387 3 4213.041043 1405.3579 Matrin-3 OS=Homo sapiens OX=9606 GN=MATR3 PE=1 SV=2 9.76 3825.4 - 601007 - - - -2.5946 - 6.068 0.71 - 660 1 2 0 -0.0109 41 0 0 0 6.72E+07 3.34E+07 - - - 10.6009 0.9999 221125_WJC_METTL3_EV_vs_WT_F06.25388.25388.4 4.41E-08 22/102 R.DGFIDKEDLHDMLASLGK.N "sp|O14950|ML12B_HUMAN,sp|P19105|ML12A_HUMAN,sp|P24844|MYL9_HUMAN,tr|J3KTJ1|J3KTJ1_HUMAN,tr|J3QRS3|J3QRS3_HUMAN" 5 2002.967 1.43 91475 25388 4 2002.967387 501.749 Myosin regulatory light chain 12B OS=Homo sapiens OX=9606 GN=MYL12B PE=1 SV=2 4.35 3825.5 - 270056 - - - 0.1972 - 3.776 0.606 - 434.2 1 2 1 0.0004 18 0 0 0 6.41E+06 4.48E+06 - - - 4.9557 0.9999 221125_WJC_METTL3_EV_vs_WT_F06.25389.25389.4 7.56E-08 32/210 K.GEAAPGPAPPAPEATPPPASAAGKDWAFINTNIFAR.T "sp|Q9NSI2|SLX9_HUMAN,tr|C9JJU7|C9JJU7_HUMAN" 2 3556.7739 0.18 91476 25389 4 3556.771734 890.2008 Ribosome biogenesis protein SLX9 homolog OS=Homo sapiens OX=9606 GN=SLX9 PE=1 SV=2 4.68 3825.6 - 3.83E+06 - - - -0.614 - 5.324 0.501 - 578.9 1 2 1 -0.0022 36 0 0 0 1.33E+08 7.46E+08 - - - 4.079 0.8946 221125_WJC_METTL3_EV_vs_WT_F06.25390.25390.4 0.000399 21/270 K.GSLGGGFSSGGFSGGSFSRGSSGGGC[160.03]FGGSSGGYGGLGGFGGGSFR.G "sp|P13645|K1C10_HUMAN,tr|A0A1B0GVI3|A0A1B0GVI3_HUMAN" 2 4030.7314 1.41 91477 25390 4 4031.70698 1008.6901 "Keratin, type I cytoskeletal 10 OS=Homo sapiens OX=9606 GN=KRT10 PE=1 SV=6" 9.5 3825.8 - 2.32E+06 - - - 242.0469 - 1.989 0.611 - 48.6 1 2 1 0.9756 46 0 0 0 7.85E+06 5.56E+06 - - - 4.4671 0.9944 221125_WJC_METTL3_EV_vs_WT_F06.25392.25392.2 0.179 18-Jun K.FLLFGIQDGK.R "sp|P22105|TENX_HUMAN,tr|A0A140TA52|A0A140TA52_HUMAN,tr|A0A140T956|A0A140T956_HUMAN,tr|A0A140TA33|A0A140TA33_HUMAN,tr|A0A140T8Y3|A0A140T8Y3_HUMAN,tr|A0A3B3ISX9|A0A3B3ISX9_HUMAN,tr|A0A140T9C0|A0A140T9C0_HUMAN,tr|A0A140T902|A0A140T902_HUMAN,tr|A0A140T8Z8|A0A140T8Z8_HUMAN,tr|A0A140TA41|A0A140TA41_HUMAN" 10 1136.623 20.35 91479 25392 2 1136.622708 569.3188 Tenascin-X OS=Homo sapiens OX=9606 GN=TNXB PE=1 SV=5 5.84 3826.1 - 568304 - - - -0.2534 - 1.315 0.183 - 85.4 2 2 0 -0.0003 10 0 0 0 6.62E+06 3.25E+05 - - - 1.0224 0.9999 221125_WJC_METTL3_EV_vs_WT_F06.25397.25397.3 1.33E-12 24/140 K.GEAAPGPAPPAPEATPPPASAAGKDWAFINTNIFAR.T "sp|Q9NSI2|SLX9_HUMAN,tr|C9JJU7|C9JJU7_HUMAN" 2 3556.7739 1.34 91481 25397 3 3556.776147 1186.5986 Ribosome biogenesis protein SLX9 homolog OS=Homo sapiens OX=9606 GN=SLX9 PE=1 SV=2 4.68 3826.7 - 1.45E+06 - - - 0.6267 - 3.92 0.53 - 315.8 1 2 1 0.0022 36 0 0 0 3.15E+07 2.35E+07 - - - 7.5912 1 221125_WJC_METTL3_EV_vs_WT_F06.25408.25408.3 4.40E-19 40/160 R.LASLMNLGMSSSLNQQGAHSALSSASTSSHNLQSIFNIGSR.G "sp|P43243|MATR3_HUMAN,tr|A8MXP9|A8MXP9_HUMAN,tr|D6R991|D6R991_HUMAN,tr|D6REK4|D6REK4_HUMAN,tr|A0A0R4J2E8|A0A0R4J2E8_HUMAN,tr|D6RCM3|D6RCM3_HUMAN,tr|D6R8Z5|D6R8Z5_HUMAN,tr|D6REM6|D6REM6_HUMAN" 8 4203.0437 2.01 91486 25408 3 4203.031538 1402.0218 Matrin-3 OS=Homo sapiens OX=9606 GN=MATR3 PE=1 SV=2 9.76 3827.9 - 7.38E+06 - - - -2.8946 - 6.661 0.762 - 1091.7 1 2 0 -0.0122 41 0 0 0 6.72E+07 3.34E+07 - - - 11.3948 0.9513 221125_WJC_METTL3_EV_vs_WT_F06.25412.25412.2 0.0167 26-Aug K.GAVHDVKDVLDSVL.- sp|P81605|DCD_HUMAN 1 1465.7777 21.7 91488 25412 2 1465.772625 733.8961 Dermcidin OS=Homo sapiens OX=9606 GN=DCD PE=1 SV=2 4.41 3828.4 - 284939 - - - -3.4344 - 1.657 0.316 - 90.2 1 2 1 -0.005 14 0 0 0 1.97E+07 9.07E+05 - - - 2.6407 1 221125_WJC_METTL3_EV_vs_WT_F06.25430.25430.4 8.85E-13 44/240 R.LASLMNLGMSSSLNQQGAHSALSSASTSSHNLQSIFNIGSR[166.11].G "sp|P43243|MATR3_HUMAN,tr|A8MXP9|A8MXP9_HUMAN,tr|D6R991|D6R991_HUMAN,tr|D6REK4|D6REK4_HUMAN,tr|A0A0R4J2E8|A0A0R4J2E8_HUMAN,tr|D6RCM3|D6RCM3_HUMAN,tr|D6R8Z5|D6R8Z5_HUMAN,tr|D6REM6|D6REM6_HUMAN" 8 4213.052 1.71 91495 25430 4 4213.040341 1054.2703 Matrin-3 OS=Homo sapiens OX=9606 GN=MATR3 PE=1 SV=2 9.76 3830.8 - 3.79E+07 - - - -2.7612 - 5.922 0.638 - 710 1 2 0 -0.0116 41 0 0 0 3.43E+09 2.00E+09 - - - 5.2869 1 221125_WJC_METTL3_EV_vs_WT_F06.25434.25434.3 1.60E-12 27/112 K.APLATGEDDDDEVPDLVENFDEASKNEAN.- "sp|P20290|BTF3_HUMAN,tr|A0A7I2V5Y3|A0A7I2V5Y3_HUMAN" 2 3118.3375 1.25 91496 25434 3 3118.336541 1040.4531 Transcription factor BTF3 OS=Homo sapiens OX=9606 GN=BTF3 PE=1 SV=1 3.42 3831.4 - 2.22E+06 - - - -0.2941 - 4.591 0.706 - 546.9 1 2 1 -0.0009 29 0 0 0 3.87E+08 3.10E+08 - - - 9.9173 1 221125_WJC_METTL3_EV_vs_WT_F06.25446.25446.4 3.96E-09 22/102 K.STSESFIQHIVSLVHHVK.E "sp|Q9NYF8|BCLF1_HUMAN,tr|E9PKI6|E9PKI6_HUMAN,tr|A0A1W2PQ43|A0A1W2PQ43_HUMAN,tr|E9PK91|E9PK91_HUMAN,tr|E9PJA7|E9PJA7_HUMAN,tr|E9PK09|E9PK09_HUMAN,tr|E9PQN2|E9PQN2_HUMAN" 7 2047.0851 2.09 91500 25446 4 2047.083237 512.7785 Bcl-2-associated transcription factor 1 OS=Homo sapiens OX=9606 GN=BCLAF1 PE=1 SV=2 6.78 3833.1 - 713178 - - - -0.8974 - 3.795 0.598 - 295.2 1 2 0 -0.0018 18 0 0 0 1.26E+09 6.03E+08 - - - 4.8873 1 221125_WJC_METTL3_EV_vs_WT_F06.25451.25451.4 7.49E-13 16/102 K.STSESFIQHIVSLVHHVK[136.11].E "sp|Q9NYF8|BCLF1_HUMAN,tr|E9PKI6|E9PKI6_HUMAN,tr|A0A1W2PQ43|A0A1W2PQ43_HUMAN,tr|E9PK91|E9PK91_HUMAN,tr|E9PJA7|E9PJA7_HUMAN,tr|E9PK09|E9PK09_HUMAN,tr|E9PQN2|E9PQN2_HUMAN" 7 2055.0993 2.09 91503 25451 4 2055.097571 514.7821 Bcl-2-associated transcription factor 1 OS=Homo sapiens OX=9606 GN=BCLAF1 PE=1 SV=2 6.78 3833.8 - 489995 - - - -0.8287 - 3.381 0.641 - 168.7 1 2 0 -0.0017 18 0 0 0 1.26E+09 6.04E+08 - - - 5.2221 1 221125_WJC_METTL3_EV_vs_WT_F06.25459.25459.3 1.20E-09 16/68 K.YVHYEIDAC[160.03]MDSEAPGSK[136.11].D "sp|Q86U44|MTA70_HUMAN,tr|H0YFV6|H0YFV6_HUMAN" 2 2078.8805 0.001 91507 25459 3 2078.874645 693.9674 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 4.31 3834.7 - 664278 - - - -2.8126 - 3.19 0.664 - 273.8 1 2 0 -0.0058 18 0 0 0 0.00E+00 3.11E+07 - - - 8.8299 0.9956 221125_WJC_METTL3_EV_vs_WT_F06.25465.25465.3 3.60E-07 18/148 R.AAASSYNTQGAASSLGSYGAQAASYGAQSAASSLAYGA.Q sp|Q96PK6|RBM14_HUMAN 1 3487.5764 - 91509 25465 3 3487.571867 1163.5327 RNA-binding protein 14 OS=Homo sapiens OX=9606 GN=RBM14 PE=1 SV=2 5.57 3835.5 - 1.07E+06 - - - -1.2998 - 3.666 0.425 - 163.4 1 1 0 -0.0045 38 0 0 0 - - - - - 6.2658 1 221125_WJC_METTL3_EV_vs_WT_F06.25467.25467.4 1.43E-08 23/216 K.FTSSQTQSPTPPKPPSPSFELGLSSFPPLPGAAGNLK.T "sp|Q92615|LAR4B_HUMAN,tr|H0Y4V9|H0Y4V9_HUMAN" 2 3765.9254 2.16 91511 25467 4 3765.922392 942.4886 La-related protein 4B OS=Homo sapiens OX=9606 GN=LARP4B PE=1 SV=3 8.59 3835.8 - 1.25E+06 - - - -0.7969 - 3.507 0.567 - 127.8 1 2 0 -0.003 37 0 0 0 1.00E+08 4.64E+07 - - - 4.5282 0.9981 221125_WJC_METTL3_EV_vs_WT_F06.25468.25468.4 1.45E-11 22/96 T.RTHNLEPYFESFINNLR.R sp|P04264|K2C1_HUMAN 1 2149.0705 119.89 91512 25468 4 2149.071861 538.2749 "Keratin, type II cytoskeletal 1 OS=Homo sapiens OX=9606 GN=KRT1 PE=1 SV=6" 6.76 3835.9 - 570234 - - - 0.6393 - 3.626 0.577 - 467.3 1 1 0 0.0014 17 0 0 0 4.12E+08 3.44E+06 - - - 4.6951 1 221125_WJC_METTL3_EV_vs_WT_F06.25471.25471.4 1.40E-14 28/174 K.KSEAAVPPWVDTNDEETIQQQILALSADKR.N sp|Q96A49|SYAP1_HUMAN 1 3351.6947 2.47 91513 25471 4 3351.697769 838.9309 Synapse-associated protein 1 OS=Homo sapiens OX=9606 GN=SYAP1 PE=1 SV=1 4.3 3836.3 - 1.90E+06 - - - 0.9264 - 4.399 0.706 - 346.8 1 2 0 0.0031 30 0 0 0 5.43E+08 2.20E+08 - - - 5.8235 1 221125_WJC_METTL3_EV_vs_WT_F06.25472.25472.4 1.77E-11 30/174 K.K[136.11]SEAAVPPWVDTNDEETIQQQILALSADK[136.11]R[166.11].N sp|Q96A49|SYAP1_HUMAN 1 3377.7313 2.33 91514 25472 4 3377.729013 845.4401 Synapse-associated protein 1 OS=Homo sapiens OX=9606 GN=SYAP1 PE=1 SV=1 4.3 3836.4 - 994186 - - - -0.6871 - 4.432 0.677 - 374.8 1 2 0 -0.0023 30 0 0 0 1.09E+08 4.69E+07 - - - 5.5736 0.9982 221125_WJC_METTL3_EV_vs_WT_F06.25476.25476.4 8.45E-09 30/174 F.GR[166.11]PHNVQPNWITLGNQLDGIHLLDPDVVAR[166.11].F sp|Q86U44|MTA70_HUMAN 1 3363.7703 0 91516 25476 4 3363.767632 841.9499 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 5.99 3836.9 - 2.41E+06 - - - -0.8024 - 5.125 0.577 - 430.8 1 1 0 -0.0027 30 0 0 0 1.34E+06 4.61E+08 - - - 4.7475 1 221125_WJC_METTL3_EV_vs_WT_F06.25478.25478.3 2.18E-09 20/68 K.STSESFIQHIVSLVHHVK.E "sp|Q9NYF8|BCLF1_HUMAN,tr|E9PKI6|E9PKI6_HUMAN,tr|A0A1W2PQ43|A0A1W2PQ43_HUMAN,tr|E9PK91|E9PK91_HUMAN,tr|E9PJA7|E9PJA7_HUMAN,tr|E9PK09|E9PK09_HUMAN,tr|E9PQN2|E9PQN2_HUMAN" 7 2047.0851 2.01 91518 25478 3 2047.085888 683.369 Bcl-2-associated transcription factor 1 OS=Homo sapiens OX=9606 GN=BCLAF1 PE=1 SV=2 6.78 3837.1 - 2.91E+06 - - - 0.3976 - 3.713 0.611 - 524.3 1 2 0 0.0008 18 0 0 0 3.54E+08 1.76E+08 - - - 8.6184 1 221125_WJC_METTL3_EV_vs_WT_F06.25479.25479.4 3.15E-10 20/174 K.DNQVVQLHPSTVLDHKPEWVLYNEFVLTTK.N sp|O43143|DHX15_HUMAN 1 3548.8304 1.27 91519 25479 4 3548.831544 888.2149 Pre-mRNA-splicing factor ATP-dependent RNA helicase DHX15 OS=Homo sapiens OX=9606 GN=DHX15 PE=1 SV=2 5.31 3837.2 - 1.21E+06 - - - 0.3308 - 3.768 0.565 - 193.1 1 2 0 0.0012 30 0 0 0 3.44E+07 2.71E+07 - - - 4.5494 1 221125_WJC_METTL3_EV_vs_WT_F06.25484.25484.3 2.67E-11 17/68 K.STSESFIQHIVSLVHHVK[136.11].E "sp|Q9NYF8|BCLF1_HUMAN,tr|E9PKI6|E9PKI6_HUMAN,tr|A0A1W2PQ43|A0A1W2PQ43_HUMAN,tr|E9PK91|E9PK91_HUMAN,tr|E9PJA7|E9PJA7_HUMAN,tr|E9PK09|E9PK09_HUMAN,tr|E9PQN2|E9PQN2_HUMAN" 7 2055.0993 2.04 91521 25484 3 2055.100385 686.0404 Bcl-2-associated transcription factor 1 OS=Homo sapiens OX=9606 GN=BCLAF1 PE=1 SV=2 6.78 3837.9 - 858678 - - - 0.5406 - 3.502 0.685 - 447.2 1 2 0 0.0011 18 0 0 0 3.61E+08 1.77E+08 - - - 9.2977 0.9998 221125_WJC_METTL3_EV_vs_WT_F06.25489.25489.3 0.0445 Nov-72 K.ILTATVDNANILLQIDNAR.L "sp|Q04695|K1C17_HUMAN,tr|K7EPJ9|K7EPJ9_HUMAN,tr|F5GWP8|F5GWP8_HUMAN" 3 2067.1324 999 91524 25489 3 2067.132012 690.0514 "Keratin, type I cytoskeletal 17 OS=Homo sapiens OX=9606 GN=KRT17 PE=1 SV=2" 4.21 3838.5 - 278829 - - - -0.1964 - 2.425 0.348 - 153.2 1 2 0 -0.0004 19 0 0 0 1.93E+06 0.00E+00 - - - 4.5961 1 221125_WJC_METTL3_EV_vs_WT_F06.25491.25491.4 1.57E-07 23/216 K.FTSSQTQSPTPPK[136.11]PPSPSFELGLSSFPPLPGAAGNLK[136.11].T "sp|Q92615|LAR4B_HUMAN,tr|H0Y4V9|H0Y4V9_HUMAN" 2 3781.9538 2.16 91526 25491 4 3781.953591 946.4957 La-related protein 4B OS=Homo sapiens OX=9606 GN=LARP4B PE=1 SV=3 8.59 3838.8 - 1.37E+06 - - - -0.0534 - 2.967 0.498 - 134 1 2 0 -0.0002 37 0 0 0 1.00E+08 4.64E+07 - - - 3.8794 0.9985 221125_WJC_METTL3_EV_vs_WT_F06.25494.25494.3 6.63E-10 18/60 T.SESFIQHIVSLVHHVK.E "sp|Q9NYF8|BCLF1_HUMAN,tr|E9PKI6|E9PKI6_HUMAN,tr|A0A1W2PQ43|A0A1W2PQ43_HUMAN,tr|E9PK91|E9PK91_HUMAN,tr|E9PJA7|E9PJA7_HUMAN,tr|E9PK09|E9PK09_HUMAN,tr|E9PQN2|E9PQN2_HUMAN" 7 1859.0054 1.98 91529 25494 3 1859.008323 620.6757 Bcl-2-associated transcription factor 1 OS=Homo sapiens OX=9606 GN=BCLAF1 PE=1 SV=2 6.78 3839.1 - 800956 - - - 1.5901 - 3.156 0.624 - 292.7 1 1 0 0.003 16 0 0 0 2.84E+07 1.44E+07 - - - 8.4451 0.9985 221125_WJC_METTL3_EV_vs_WT_F06.25495.25495.3 1.59E-06 17/44 F.IQHIVSLVHHVK.E "sp|Q9NYF8|BCLF1_HUMAN,tr|E9PKI6|E9PKI6_HUMAN,tr|A0A1W2PQ43|A0A1W2PQ43_HUMAN,tr|E9PK91|E9PK91_HUMAN,tr|E9PJA7|E9PJA7_HUMAN,tr|E9PK09|E9PK09_HUMAN,tr|E9PQN2|E9PQN2_HUMAN" 7 1408.8303 1.95 91530 25495 3 1408.830524 470.6174 Bcl-2-associated transcription factor 1 OS=Homo sapiens OX=9606 GN=BCLAF1 PE=1 SV=2 8.77 3839.3 - 484988 - - - 0.1569 - 2.817 0.556 - 297.7 1 1 0 0.0002 12 0 0 0 1.75E+07 8.96E+06 - - - 7.6095 1 221125_WJC_METTL3_EV_vs_WT_F06.25507.25507.3 9.99E-09 17/60 T.SESFIQHIVSLVHHVK[136.11].E "sp|Q9NYF8|BCLF1_HUMAN,tr|E9PKI6|E9PKI6_HUMAN,tr|A0A1W2PQ43|A0A1W2PQ43_HUMAN,tr|E9PK91|E9PK91_HUMAN,tr|E9PJA7|E9PJA7_HUMAN,tr|E9PK09|E9PK09_HUMAN,tr|E9PQN2|E9PQN2_HUMAN" 7 1867.0196 2.27 91535 25507 3 1867.017647 623.3471 Bcl-2-associated transcription factor 1 OS=Homo sapiens OX=9606 GN=BCLAF1 PE=1 SV=2 6.78 3841 - 828226 - - - -1.0284 - 3.142 0.628 - 318.5 1 1 0 -0.0019 16 0 0 0 2.86E+07 1.26E+07 - - - 8.4786 0.9988 221125_WJC_METTL3_EV_vs_WT_F06.25510.25510.3 2.95E-06 17/44 F.IQHIVSLVHHVK[136.11].E "sp|Q9NYF8|BCLF1_HUMAN,tr|E9PKI6|E9PKI6_HUMAN,tr|A0A1W2PQ43|A0A1W2PQ43_HUMAN,tr|E9PK91|E9PK91_HUMAN,tr|E9PJA7|E9PJA7_HUMAN,tr|E9PK09|E9PK09_HUMAN,tr|E9PQN2|E9PQN2_HUMAN" 7 1416.8445 1.98 91537 25510 3 1416.84371 473.2888 Bcl-2-associated transcription factor 1 OS=Homo sapiens OX=9606 GN=BCLAF1 PE=1 SV=2 8.77 3841.3 - 669207 - - - -0.5597 - 2.949 0.58 - 355 1 1 0 -0.0008 12 0 0 0 1.75E+07 8.85E+06 - - - 8.0039 1 221125_WJC_METTL3_EV_vs_WT_F06.25513.25513.3 4.30E-12 33/120 K.ELEQVC[160.03]NPIISGLYQGAGGPGPGGFGAQGPK[136.11].G "sp|P0DMV8|HS71A_HUMAN,sp|P0DMV9|HS71B_HUMAN,tr|V9GZ37|V9GZ37_HUMAN,tr|A0A0G2JIW1|A0A0G2JIW1_HUMAN" 4 3062.5011 0.07 91538 25513 3 3062.49572 1021.841 Heat shock 70 kDa protein 1A OS=Homo sapiens OX=9606 GN=HSPA1A PE=1 SV=1 4.53 3841.7 - 1.72E+06 - - - -1.7633 - 5.525 0.727 - 1181.2 1 2 0 -0.0054 31 0 0 0 5.17E+06 7.28E+07 - - - 10.5763 1 221125_WJC_METTL3_EV_vs_WT_F06.25514.25514.3 8.94E-10 24/64 T.RTHNLEPYFESFINNLR.R sp|P04264|K2C1_HUMAN 1 2149.0705 538.05 91539 25514 3 2149.07133 717.3641 "Keratin, type II cytoskeletal 1 OS=Homo sapiens OX=9606 GN=KRT1 PE=1 SV=6" 6.76 3841.8 - 1.87E+06 - - - 0.3923 - 4.234 0.613 - 1042.7 1 1 0 0.0008 17 0 0 0 3.32E+08 6.16E+05 - - - 9.0199 0.9999 221125_WJC_METTL3_EV_vs_WT_F06.25515.25515.4 5.65E-10 18/114 R.RIDEINKELNQVMEQLGDAR.L "sp|Q14683|SMC1A_HUMAN,tr|G8JLG1|G8JLG1_HUMAN,tr|A0A6Q8PHC3|A0A6Q8PHC3_HUMAN" 3 2370.1962 1.46 91540 25515 4 2370.194071 593.5563 Structural maintenance of chromosomes protein 1A OS=Homo sapiens OX=9606 GN=SMC1A PE=1 SV=2 4.51 3841.9 - 923394 - - - -0.8805 - 3.434 0.606 - 245.7 1 2 1 -0.0021 20 0 0 0 6.83E+06 4.69E+06 - - - 4.9125 0.9885 221125_WJC_METTL3_EV_vs_WT_F06.25519.25519.2 0.00153 22-Dec K.K[136.11]VSQEILELLNT.T "sp|Q86U44|MTA70_HUMAN,tr|H0YFV6|H0YFV6_HUMAN" 2 1393.7908 0.001 91542 25519 2 1393.791571 697.9027 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 4.53 3842.5 - 749166 - - - 0.556 - 2.33 0.407 - 508.2 1 1 0 0.0008 12 0 0 0 0.00E+00 1.88E+07 - - - 4.2725 1 221125_WJC_METTL3_EV_vs_WT_F06.25528.25528.4 1.07E-12 37/258 K.AQSGLAFQQTSNTQPIPILYEHQLGQASGLGGSQLIDTHLLQAR.A "sp|Q9Y520|PRC2C_HUMAN,tr|E7EPN9|E7EPN9_HUMAN,tr|H7C5N8|H7C5N8_HUMAN,tr|A0A2R8Y7F4|A0A2R8Y7F4_HUMAN,tr|A0A2R8YET2|A0A2R8YET2_HUMAN" 5 4686.4154 2.2 91546 25528 4 4686.417003 1172.6111 Protein PRRC2C OS=Homo sapiens OX=9606 GN=PRRC2C PE=1 SV=4 6 3843.5 - 3.48E+06 - - - 0.3384 - 6.106 0.673 - 354.9 1 2 0 0.0016 44 0 0 0 1.77E+08 8.04E+07 - - - 5.596 1 221125_WJC_METTL3_EV_vs_WT_F06.25532.25532.3 4.28E-10 17/136 R.VSTSPVGLPSIDPSGSSPSSSSAPLASFSGIPGTR[166.11].V "sp|Q8IWZ3|ANKH1_HUMAN,tr|H0Y472|H0Y472_HUMAN,tr|H0Y4P6|H0Y4P6_HUMAN,tr|H7C0V5|H7C0V5_HUMAN,tr|H0Y785|H0Y785_HUMAN" 5 3295.6448 0.89 91548 25532 3 3295.64516 1099.5555 Ankyrin repeat and KH domain-containing protein 1 OS=Homo sapiens OX=9606 GN=ANKHD1 PE=1 SV=1 5.81 3844 - 906357 - - - 0.1241 - 2.912 0.586 - 106.4 1 2 0 0.0004 35 0 0 0 2.43E+07 2.73E+07 - - - 7.5322 1 221125_WJC_METTL3_EV_vs_WT_F06.25533.25533.3 1.40E-15 23/112 K.DIENQYETQITQIEHEVSSSGQEVQSSAK.E "sp|P35527|K1C9_HUMAN,tr|K7EQQ3|K7EQQ3_HUMAN" 2 3263.5066 8.96 91549 25533 3 3263.511123 1088.8428 "Keratin, type I cytoskeletal 9 OS=Homo sapiens OX=9606 GN=KRT9 PE=1 SV=3" 4.14 3844.1 - 865948 - - - 1.3893 - 5.25 0.7 - 530.5 1 2 0 0.0045 29 0 0 0 1.80E+07 2.01E+06 - - - 10.158 0.9995 221125_WJC_METTL3_EV_vs_WT_F06.25534.25534.4 3.34E-06 12/114 R.R[166.11]IDEINK[136.11]ELNQVMEQLGDAR[166.11].L "sp|Q14683|SMC1A_HUMAN,tr|G8JLG1|G8JLG1_HUMAN,tr|A0A6Q8PHC3|A0A6Q8PHC3_HUMAN" 3 2398.2269 1.41 91550 25534 4 2398.226073 600.564 Structural maintenance of chromosomes protein 1A OS=Homo sapiens OX=9606 GN=SMC1A PE=1 SV=2 4.51 3844.3 - 445993 - - - -0.344 - 2.512 0.401 - 102.4 1 2 1 -0.0008 20 0 0 0 5.60E+06 3.96E+06 - - - 3.024 0.9932 221125_WJC_METTL3_EV_vs_WT_F06.25543.25543.3 0.128 Aug-52 K.AFYPEEISSMVLTK[136.11].M "sp|P0DMV8|HS71A_HUMAN,sp|P34931|HS71L_HUMAN,sp|P0DMV9|HS71B_HUMAN,tr|Q53FA3|Q53FA3_HUMAN,tr|A0A0G2JIW1|A0A0G2JIW1_HUMAN" 5 1621.8153 0.08 91556 25543 3 1621.81445 541.6124 Heat shock 70 kDa protein 1A OS=Homo sapiens OX=9606 GN=HSPA1A PE=1 SV=1 4.53 3845.4 - 267261 - - - -0.5216 - 1.411 0.232 - 42 1 2 0 -0.0008 14 0 0 0 4.70E+05 5.95E+06 - - - 2.0413 0.9989 221125_WJC_METTL3_EV_vs_WT_F06.25558.25558.3 9.91E-10 15/92 L.SVDDVNVLTC[160.03]ATGTLSNLTC[160.03]NNSK.N sp|P14923|PLAK_HUMAN 1 2582.1952 7.18 91564 25558 3 2582.19443 861.739 Junction plakoglobin OS=Homo sapiens OX=9606 GN=JUP PE=1 SV=3 4.21 3847.3 - 1.09E+06 - - - -0.3106 - 3.236 0.626 - 204.9 1 1 0 -0.0008 24 0 0 0 1.12E+07 1.55E+06 - - - 8.2466 1 221125_WJC_METTL3_EV_vs_WT_F06.25559.25559.3 1.27E-07 11/136 R.VSTSPVGLPSIDPSGSSPSSSSAPLASFSGIPGTR.V "sp|Q8IWZ3|ANKH1_HUMAN,tr|H0Y472|H0Y472_HUMAN,tr|H0Y4P6|H0Y4P6_HUMAN,tr|H7C0V5|H7C0V5_HUMAN,tr|H0Y785|H0Y785_HUMAN" 5 3285.6365 1 91565 25559 3 3285.634135 1096.2194 Ankyrin repeat and KH domain-containing protein 1 OS=Homo sapiens OX=9606 GN=ANKHD1 PE=1 SV=1 5.81 3847.4 - 572698 - - - -0.714 - 2.267 0.568 - 40.5 1 2 0 -0.0023 35 0 0 0 2.43E+07 2.44E+07 - - - 6.755 0.9999 221125_WJC_METTL3_EV_vs_WT_F06.25568.25568.4 0.00011 14/108 R.GLLQDDAHPTLVTYADHSK[136.11].L "sp|Q86U44|MTA70_HUMAN,tr|F5H6D8|F5H6D8_HUMAN,tr|H0YFV6|H0YFV6_HUMAN,tr|B4DTN4|B4DTN4_HUMAN" 4 2088.0367 0.001 91569 25568 4 2088.033956 523.0165 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 5.13 3848.7 - 542674 - - - -1.33 - 2.792 0.413 - 191.8 1 2 0 -0.0028 19 0 0 0 0.00E+00 2.30E+07 - - - 3.1673 0.9992 221125_WJC_METTL3_EV_vs_WT_F06.25570.25570.4 3.07E-05 18/132 R.GFGFVTYATVEEVDAAMNARPHK.V "sp|P09651|ROA1_HUMAN,tr|A0A7I2YQX9|A0A7I2YQX9_HUMAN,tr|A0A7I2V3W4|A0A7I2V3W4_HUMAN,tr|F8W646|F8W646_HUMAN,tr|F8VZ49|F8VZ49_HUMAN,tr|A0A7I2V3R8|A0A7I2V3R8_HUMAN,tr|F8W6I7|F8W6I7_HUMAN,tr|F8VYN5|F8VYN5_HUMAN,tr|A0A7I2V2L6|A0A7I2V2L6_HUMAN,tr|A0A7I2V3C7|A0A7I2V3C7_HUMAN,tr|A0A7I2V3W0|A0A7I2V3W0_HUMAN,tr|A0A7I2YQV3|A0A7I2YQV3_HUMAN,tr|A0A2R8Y4L2|A0A2R8Y4L2_HUMAN,tr|A0A7I2V2Z4|A0A7I2V2Z4_HUMAN,tr|A0A7I2V4M0|A0A7I2V4M0_HUMAN" 15 2509.206 1.51 91571 25570 4 2509.211344 628.3088 Heterogeneous nuclear ribonucleoprotein A1 OS=Homo sapiens OX=9606 GN=HNRNPA1 PE=1 SV=5 5.45 3848.9 - 449298 - - - 2.1321 - 2.911 0.321 - 77.2 1 2 0 0.0053 23 0 0 0 2.91E+07 1.93E+07 - - - 2.3647 1 221125_WJC_METTL3_EV_vs_WT_F06.25579.25579.4 7.37E-11 34/192 R.VEMEDAHTAVVGIPHGLEDWSFFAVYDGHAGSR.V "sp|O75688|PPM1B_HUMAN,tr|B8ZZF0|B8ZZF0_HUMAN,tr|A0A3B3IS24|A0A3B3IS24_HUMAN,tr|C9JIR6|C9JIR6_HUMAN" 4 3598.6576 3.65 91575 25579 4 3598.657583 900.6717 Protein phosphatase 1B OS=Homo sapiens OX=9606 GN=PPM1B PE=1 SV=1 4.56 3850.1 - 1.16E+06 - - - 0.0044 - 5.635 0.675 - 552.8 1 2 0 0 33 0 0 0 3.40E+08 9.33E+07 - - - 5.62 1 221125_WJC_METTL3_EV_vs_WT_F06.25584.25584.4 4.99E-12 33/258 K.AQSGLAFQQTSNTQPIPILYEHQLGQASGLGGSQLIDTHLLQAR[166.11].A "sp|Q9Y520|PRC2C_HUMAN,tr|E7EPN9|E7EPN9_HUMAN,tr|H7C5N8|H7C5N8_HUMAN,tr|A0A2R8Y7F4|A0A2R8Y7F4_HUMAN,tr|A0A2R8YET2|A0A2R8YET2_HUMAN" 5 4696.4237 2.2 91578 25584 4 4696.418261 1175.1132 Protein PRRC2C OS=Homo sapiens OX=9606 GN=PRRC2C PE=1 SV=4 6 3850.8 - 1.16E+06 - - - -1.1553 - 6.205 0.671 - 340 1 2 0 -0.0054 44 0 0 0 1.77E+08 8.04E+07 - - - 5.5821 1 221125_WJC_METTL3_EV_vs_WT_F06.25585.25585.3 3.61E-08 21/76 K.HAASDVDLEIESLLNQQSTK[136.11].E "sp|Q86U44|MTA70_HUMAN,tr|F5H6D8|F5H6D8_HUMAN,tr|H0YFV6|H0YFV6_HUMAN,tr|B4DTN4|B4DTN4_HUMAN" 4 2205.1005 0.38 91579 25585 3 2205.100027 736.0408 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 4.31 3850.9 - 898848 - - - -0.1945 - 4.118 0.617 - 521.2 1 2 0 -0.0004 20 0 0 0 1.88E+07 4.96E+07 - - - 8.8525 0.9999 221125_WJC_METTL3_EV_vs_WT_F06.25586.25586.4 0.00317 18/132 R.GFGFVTYATVEEVDAAMNAR[166.11]PHK[136.11].V "sp|P09651|ROA1_HUMAN,tr|A0A7I2YQX9|A0A7I2YQX9_HUMAN,tr|A0A7I2V3W4|A0A7I2V3W4_HUMAN,tr|F8W646|F8W646_HUMAN,tr|F8VZ49|F8VZ49_HUMAN,tr|A0A7I2V3R8|A0A7I2V3R8_HUMAN,tr|F8W6I7|F8W6I7_HUMAN,tr|F8VYN5|F8VYN5_HUMAN,tr|A0A7I2V2L6|A0A7I2V2L6_HUMAN,tr|A0A7I2V3C7|A0A7I2V3C7_HUMAN,tr|A0A7I2V3W0|A0A7I2V3W0_HUMAN,tr|A0A7I2YQV3|A0A7I2YQV3_HUMAN,tr|A0A2R8Y4L2|A0A2R8Y4L2_HUMAN,tr|A0A7I2V2Z4|A0A7I2V2Z4_HUMAN,tr|A0A7I2V4M0|A0A7I2V4M0_HUMAN" 15 2527.2285 1.48 91580 25586 4 2527.223635 632.8144 Heterogeneous nuclear ribonucleoprotein A1 OS=Homo sapiens OX=9606 GN=HNRNPA1 PE=1 SV=5 5.45 3851 - 500410 - - - -1.9108 - 3.358 0.469 - 183.6 1 2 0 -0.0048 23 0 0 0 2.83E+07 1.92E+07 - - - 3.6993 1 221125_WJC_METTL3_EV_vs_WT_F06.25601.25601.4 4.66E-18 44/192 R.VEMEDAHTAVVGIPHGLEDWSFFAVYDGHAGSR[166.11].V "sp|O75688|PPM1B_HUMAN,tr|B8ZZF0|B8ZZF0_HUMAN,tr|A0A3B3IS24|A0A3B3IS24_HUMAN,tr|C9JIR6|C9JIR6_HUMAN" 4 3608.6658 3.65 91587 25601 4 3608.655391 903.1737 Protein phosphatase 1B OS=Homo sapiens OX=9606 GN=PPM1B PE=1 SV=1 4.56 3853 - 1.53E+06 - - - -2.8947 - 6.093 0.703 - 1245.3 1 2 0 -0.0104 33 0 0 0 3.40E+08 9.31E+07 - - - 5.8842 0.9981 221125_WJC_METTL3_EV_vs_WT_F06.25605.25605.4 4.33E-05 12/126 K.EVTQLRHGVQELEIELQSQLSK.K "sp|P35527|K1C9_HUMAN,tr|K7EQQ3|K7EQQ3_HUMAN" 2 2563.3606 0.84 91588 25605 4 2563.352877 641.8474 "Keratin, type I cytoskeletal 9 OS=Homo sapiens OX=9606 GN=KRT9 PE=1 SV=3" 4.91 3853.6 - 420180 - - - -3.005 - 2.586 0.391 - 90.1 1 2 1 -0.0077 22 0 0 0 6.99E+06 8.29E+06 - - - 2.938 0.9919 221125_WJC_METTL3_EV_vs_WT_F06.25626.25626.2 9.05E-05 13/24 K.TLNDELEIIEGMK.F "sp|P10809|CH60_HUMAN,tr|A0A7I2V2X6|A0A7I2V2X6_HUMAN,tr|A0A7I2V599|A0A7I2V599_HUMAN,tr|E7EXB4|E7EXB4_HUMAN,tr|A0A7I2YQ71|A0A7I2YQ71_HUMAN,tr|E7ESH4|E7ESH4_HUMAN,tr|A0A7I2V5M1|A0A7I2V5M1_HUMAN,tr|A0A7I2V5K3|A0A7I2V5K3_HUMAN,tr|A0A7I2V369|A0A7I2V369_HUMAN" 9 1503.7491 1.98 91596 25626 2 1503.738094 752.8818 "60 kDa heat shock protein, mitochondrial OS=Homo sapiens OX=9606 GN=HSPD1 PE=1 SV=2" 4 3856.6 - 743373 - - - -7.2931 - 2.38 0.571 - 241.1 1 2 0 -0.011 13 0 0 0 3.07E+07 1.55E+07 - - - 5.4804 0.9804 221125_WJC_METTL3_EV_vs_WT_F06.25633.25633.4 0.000307 20/240 R.AAASSYNTQGAASSLGSYGAQAASYGAQSAASSLAYGAQAA.S sp|Q96PK6|RBM14_HUMAN 1 3757.7092 - 91599 25633 4 3757.699756 940.4346 RNA-binding protein 14 OS=Homo sapiens OX=9606 GN=RBM14 PE=1 SV=2 5.57 3857.6 - 812995 - - - -2.5146 - 3.966 0.428 - 170.1 1 1 0 -0.0094 41 0 0 0 - - - - - 3.3445 0.9966 221125_WJC_METTL3_EV_vs_WT_F06.25636.25636.3 3.44E-07 16/160 R.AAASSYNTQGAASSLGSYGAQAASYGAQSAASSLAYGAQAA.S sp|Q96PK6|RBM14_HUMAN 1 3757.7092 - 91600 25636 3 3757.70337 1253.577 RNA-binding protein 14 OS=Homo sapiens OX=9606 GN=RBM14 PE=1 SV=2 5.57 3858 - 652799 - - - -1.5528 - 3.086 0.506 - 148.9 1 1 0 -0.0058 41 0 0 0 - - - - - 6.7723 1 221125_WJC_METTL3_EV_vs_WT_F06.25638.25638.4 1.14E-15 34/198 R.LGQHVPTLHPTSEELTIAGMTFTTFDLGGHVQAR.R "sp|Q9Y6B6|SAR1B_HUMAN,tr|D6RAA2|D6RAA2_HUMAN,tr|D6RD69|D6RD69_HUMAN,tr|D6RDB2|D6RDB2_HUMAN" 4 3660.8359 1.19 91601 25638 4 3660.841833 916.2162 GTP-binding protein SAR1b OS=Homo sapiens OX=9606 GN=SAR1B PE=1 SV=1 5.75 3858.2 - 1.10E+06 - - - 1.63 - 5.307 0.695 - 844.1 1 2 0 0.006 34 0 0 0 2.49E+07 2.09E+07 - - - 5.7713 1 221125_WJC_METTL3_EV_vs_WT_F06.25639.25639.3 3.05E-14 19/128 R.VEMEDAHTAVVGIPHGLEDWSFFAVYDGHAGSR.V "sp|O75688|PPM1B_HUMAN,tr|B8ZZF0|B8ZZF0_HUMAN,tr|A0A3B3IS24|A0A3B3IS24_HUMAN,tr|C9JIR6|C9JIR6_HUMAN" 4 3598.6576 999 91602 25639 3 3598.653021 1200.5598 Protein phosphatase 1B OS=Homo sapiens OX=9606 GN=PPM1B PE=1 SV=1 4.56 3858.3 - 301016 - - - -1.2632 - 4.317 0.627 - 251.7 1 2 0 -0.0045 33 0 0 0 9.32E+06 0.00E+00 - - - 8.894 1 221125_WJC_METTL3_EV_vs_WT_F06.25654.25654.3 2.01E-11 26/100 K.YQDEYGVSSIIPNFQISQDSVGNSNR.S sp|Q8WVD3|RN138_HUMAN 1 2916.3526 1.94 91609 25654 3 2916.352269 973.1248 E3 ubiquitin-protein ligase RNF138 OS=Homo sapiens OX=9606 GN=RNF138 PE=1 SV=1 4.03 3860.5 - 2.98E+06 - - - -0.1118 - 3.752 0.651 - 532.7 1 2 0 -0.0003 26 0 0 0 1.15E+08 5.94E+07 - - - 8.84 0.9994 221125_WJC_METTL3_EV_vs_WT_F06.25662.25662.2 0.00181 18-Aug K.LLEPVLLLGK.E "sp|P62249|RS16_HUMAN,tr|M0R210|M0R210_HUMAN,tr|M0R3H0|M0R3H0_HUMAN,tr|M0QX76|M0QX76_HUMAN,tr|M0R1M5|M0R1M5_HUMAN,tr|Q6IPX4|Q6IPX4_HUMAN" 6 1093.7111 0.91 91612 25662 2 1093.711758 547.8628 40S ribosomal protein S16 OS=Homo sapiens OX=9606 GN=RPS16 PE=1 SV=2 6 3861.5 - 148188 - - - 0.6172 - 1.579 0.366 - 138 1 2 0 0.0007 10 0 0 0 5.23E+06 5.76E+06 - - - 3.0191 0.9981 221125_WJC_METTL3_EV_vs_WT_F06.25668.25668.4 0.101 12/114 K.LSSSIIHEIDSILGNK[136.11]PYSK[136.11].K "sp|Q13303|KCAB2_HUMAN,tr|A0A5F9UN28|A0A5F9UN28_HUMAN,tr|A0A590UJB6|A0A590UJB6_HUMAN" 3 2216.2023 1.84 91615 25668 4 2216.199232 555.0579 Voltage-gated potassium channel subunit beta-2 OS=Homo sapiens OX=9606 GN=KCNAB2 PE=1 SV=2 6.75 3862.1 - 197428 - - - -1.4065 - 1.809 0.272 - 102.4 1 2 0 -0.0031 20 0 0 0 1.43E+08 7.79E+07 - - - 1.7908 0.9949 221125_WJC_METTL3_EV_vs_WT_F06.25671.25671.4 2.03E-07 20/240 R.LASLMNLGMSSSLNQQGAHSALSSASTSSHNLQSIFNIGSR[166.11].G "sp|P43243|MATR3_HUMAN,tr|A8MXP9|A8MXP9_HUMAN,tr|D6R991|D6R991_HUMAN,tr|D6REK4|D6REK4_HUMAN,tr|A0A0R4J2E8|A0A0R4J2E8_HUMAN,tr|D6RCM3|D6RCM3_HUMAN,tr|D6R8Z5|D6R8Z5_HUMAN,tr|D6REM6|D6REM6_HUMAN" 8 4213.052 0.88 91616 25671 4 4214.038834 1054.2703 Matrin-3 OS=Homo sapiens OX=9606 GN=MATR3 PE=1 SV=2 9.76 3862.5 - 373547 - - - 234.2387 - 3.854 0.551 - 136.7 1 2 0 0.9869 41 0 0 0 1.44E+07 1.63E+07 - - - 4.1361 0.997 221125_WJC_METTL3_EV_vs_WT_F06.25672.25672.4 0.0337 14/114 K.LSSSIIHEIDSILGNKPYSK.K "sp|Q13303|KCAB2_HUMAN,tr|A0A5F9UN28|A0A5F9UN28_HUMAN,tr|A0A590UJB6|A0A590UJB6_HUMAN" 3 2200.1739 1.84 91617 25672 4 2200.177277 551.0508 Voltage-gated potassium channel subunit beta-2 OS=Homo sapiens OX=9606 GN=KCNAB2 PE=1 SV=2 6.75 3862.6 - 381162 - - - 1.5126 - 2.254 0.25 - 150.8 1 2 0 0.0033 20 0 0 0 1.43E+08 7.79E+07 - - - 1.6728 0.9979 221125_WJC_METTL3_EV_vs_WT_F06.25688.25688.4 0.0352 5/102 K.STSESFIQHIVSLVHHVK.E "sp|Q9NYF8|BCLF1_HUMAN,tr|E9PKI6|E9PKI6_HUMAN,tr|A0A1W2PQ43|A0A1W2PQ43_HUMAN,tr|E9PK91|E9PK91_HUMAN,tr|E9PJA7|E9PJA7_HUMAN,tr|E9PK09|E9PK09_HUMAN,tr|E9PQN2|E9PQN2_HUMAN" 7 2047.0851 3.56 91622 25688 4 2047.084672 512.7785 Bcl-2-associated transcription factor 1 OS=Homo sapiens OX=9606 GN=BCLAF1 PE=1 SV=2 6.78 3864.9 - 155002 - - - -0.1964 - 1.433 0.317 - 14 3 2 0 -0.0004 18 0 0 0 6.78E+06 1.90E+06 - - - 1.7447 0.9599 221125_WJC_METTL3_EV_vs_WT_F06.25690.25690.4 0.0807 9/126 R.EFASHLQQLQDALNELTEEHSK[136.11].A "sp|Q14980|NUMA1_HUMAN,tr|A0A087WY61|A0A087WY61_HUMAN,tr|F5H4J1|F5H4J1_HUMAN,tr|F5H6Y5|F5H6Y5_HUMAN" 4 2574.2442 0.91 91623 25690 4 2574.249181 644.5683 Nuclear mitotic apparatus protein 1 OS=Homo sapiens OX=9606 GN=NUMA1 PE=1 SV=2 4.56 3865.1 - 520251 - - - 1.9505 - 1.681 0.165 - 37.5 1 2 0 0.005 22 0 0 0 1.63E+07 1.80E+07 - - - 0.8307 1 221125_WJC_METTL3_EV_vs_WT_F06.25692.25692.3 6.16E-12 23/76 K.LSSSIIHEIDSILGNK[136.11]PYSK[136.11].K "sp|Q13303|KCAB2_HUMAN,tr|A0A5F9UN28|A0A5F9UN28_HUMAN,tr|A0A590UJB6|A0A590UJB6_HUMAN" 3 2216.2023 1.55 91624 25692 3 2216.205187 739.7414 Voltage-gated potassium channel subunit beta-2 OS=Homo sapiens OX=9606 GN=KCNAB2 PE=1 SV=2 6.75 3865.5 - 512526 - - - 1.2806 - 4.301 0.637 - 564.2 1 2 0 0.0028 20 0 0 0 4.54E+07 2.93E+07 - - - 9.1803 1 221125_WJC_METTL3_EV_vs_WT_F06.25696.25696.4 3.24E-09 19/96 R.THNLEPYFESFINNLRR.R sp|P04264|K2C1_HUMAN 1 2149.0705 1446.03 91626 25696 4 2149.074023 538.2749 "Keratin, type II cytoskeletal 1 OS=Homo sapiens OX=9606 GN=KRT1 PE=1 SV=6" 6.42 3866 - 1.01E+07 - - - 1.6454 - 3.294 0.567 - 336.4 1 2 0 0.0035 17 0 0 0 3.63E+08 2.51E+05 - - - 4.5741 0.9999 221125_WJC_METTL3_EV_vs_WT_F06.25698.25698.4 9.38E-12 19/132 K.SRLEVSDDLENVC[160.03]NWVVDTC[160.03]LHK.G "sp|O75688|PPM1B_HUMAN,tr|A0A3B3IS24|A0A3B3IS24_HUMAN,tr|C9JIR6|C9JIR6_HUMAN" 3 2787.2956 1.47 91627 25698 4 2787.29963 697.8312 Protein phosphatase 1B OS=Homo sapiens OX=9606 GN=PPM1B PE=1 SV=1 4.43 3866.2 - 681908 - - - 1.4408 - 3.807 0.604 - 189.1 1 2 1 0.004 23 0 0 0 2.12E+07 1.45E+07 - - - 4.9152 0.9999 221125_WJC_METTL3_EV_vs_WT_F06.25703.25703.4 9.91E-08 20/126 R.EFASHLQQLQDALNELTEEHSK.A "sp|Q14980|NUMA1_HUMAN,tr|A0A087WY61|A0A087WY61_HUMAN,tr|F5H4J1|F5H4J1_HUMAN,tr|F5H6Y5|F5H6Y5_HUMAN" 4 2566.23 0.91 91629 25703 4 2566.236332 642.5648 Nuclear mitotic apparatus protein 1 OS=Homo sapiens OX=9606 GN=NUMA1 PE=1 SV=2 4.56 3866.9 - 316077 - - - 2.483 - 3.827 0.514 - 218.9 1 2 0 0.0064 22 0 0 0 1.63E+07 1.80E+07 - - - 4.1372 0.9913 221125_WJC_METTL3_EV_vs_WT_F06.25708.25708.4 2.29E-07 28/240 R.LASLMNLGMSSSLNQQGAHSALSSASTSSHNLQSIFNIGSR.G "sp|P43243|MATR3_HUMAN,tr|A8MXP9|A8MXP9_HUMAN,tr|D6R991|D6R991_HUMAN,tr|D6REK4|D6REK4_HUMAN,tr|A0A0R4J2E8|A0A0R4J2E8_HUMAN,tr|D6RCM3|D6RCM3_HUMAN,tr|D6R8Z5|D6R8Z5_HUMAN,tr|D6REM6|D6REM6_HUMAN" 8 4203.0437 0.67 91632 25708 4 4204.027876 1051.7682 Matrin-3 OS=Homo sapiens OX=9606 GN=MATR3 PE=1 SV=2 9.76 3867.5 - 1.02E+06 - - - 234.157 - 5.068 0.536 - 269.2 1 2 0 0.9842 41 0 0 0 9.38E+06 1.40E+07 - - - 4.0849 0.9998 221125_WJC_METTL3_EV_vs_WT_F06.25710.25710.4 1.23E-08 17/108 R.ADLEMQIENLKEELAYLKK.N "sp|Q04695|K1C17_HUMAN,tr|K7EPJ9|K7EPJ9_HUMAN,tr|F5GWP8|F5GWP8_HUMAN" 3 2277.1926 92.22 91633 25710 4 2277.199648 570.3054 "Keratin, type I cytoskeletal 17 OS=Homo sapiens OX=9606 GN=KRT17 PE=1 SV=2" 4.59 3867.7 - 631190 - - - 3.0797 - 3.553 0.569 - 312.4 1 2 1 0.007 19 0 0 0 2.36E+07 2.56E+05 - - - 4.6055 1 221125_WJC_METTL3_EV_vs_WT_F06.25712.25712.3 2.62E-08 34/76 K.LSSSIIHEIDSILGNKPYSK.K "sp|Q13303|KCAB2_HUMAN,tr|A0A5F9UN28|A0A5F9UN28_HUMAN,tr|A0A590UJB6|A0A590UJB6_HUMAN" 3 2200.1739 1.56 91635 25712 3 2200.178047 734.3986 Voltage-gated potassium channel subunit beta-2 OS=Homo sapiens OX=9606 GN=KCNAB2 PE=1 SV=2 6.75 3868 - 2.39E+06 - - - 1.8626 - 5.297 0.64 - 1330.9 1 2 0 0.0041 20 0 0 0 4.54E+07 2.92E+07 - - - 9.7188 0.9996 221125_WJC_METTL3_EV_vs_WT_F06.25717.25717.3 1.89E-08 17/68 K.YVHYEIDAC[160.03]MDSEAPGSK[136.11].D "sp|Q86U44|MTA70_HUMAN,tr|H0YFV6|H0YFV6_HUMAN" 2 2078.8805 0 91637 25717 3 2079.880787 693.9674 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 4.31 3868.7 - 562936 - - - 481.17 - 3.316 0.619 - 327 1 2 0 1.0003 18 0 0 0 1.34E+05 6.68E+07 - - - 8.1492 0.9997 221125_WJC_METTL3_EV_vs_WT_F06.25719.25719.3 7.47E-07 16/88 K.SRLEVSDDLENVC[160.03]NWVVDTC[160.03]LHK.G "sp|O75688|PPM1B_HUMAN,tr|A0A3B3IS24|A0A3B3IS24_HUMAN,tr|C9JIR6|C9JIR6_HUMAN" 3 2787.2956 999 91639 25719 3 2787.286601 930.1058 Protein phosphatase 1B OS=Homo sapiens OX=9606 GN=PPM1B PE=1 SV=1 4.43 3868.9 - 235995 - - - -3.2336 - 3.143 0.586 - 280.2 1 2 1 -0.009 23 0 0 0 1.04E+06 0.00E+00 - - - 7.7573 0.9954 221125_WJC_METTL3_EV_vs_WT_F06.25725.25725.4 0.00204 Sep-90 K.STSESFIQHIVSLVHH.V "sp|Q9NYF8|BCLF1_HUMAN,tr|E9PKI6|E9PKI6_HUMAN,tr|A0A1W2PQ43|A0A1W2PQ43_HUMAN,tr|E9PK91|E9PK91_HUMAN,tr|E9PJA7|E9PJA7_HUMAN,tr|E9PK09|E9PK09_HUMAN,tr|E9PQN2|E9PQN2_HUMAN" 7 1819.9217 - 91643 25725 4 1819.922312 455.9877 Bcl-2-associated transcription factor 1 OS=Homo sapiens OX=9606 GN=BCLAF1 PE=1 SV=2 6.2 3869.7 - 333300 - - - 0.3379 - 2.284 0.497 - 64 1 1 0 0.0006 16 0 0 0 - - - - - 3.8427 0.9937 221125_WJC_METTL3_EV_vs_WT_F06.25727.25727.3 9.14E-05 Dec-60 K.STSESFIQHIVSLVHH.V "sp|Q9NYF8|BCLF1_HUMAN,tr|E9PKI6|E9PKI6_HUMAN,tr|A0A1W2PQ43|A0A1W2PQ43_HUMAN,tr|E9PK91|E9PK91_HUMAN,tr|E9PJA7|E9PJA7_HUMAN,tr|E9PK09|E9PK09_HUMAN,tr|E9PQN2|E9PQN2_HUMAN" 7 1819.9217 - 91645 25727 3 1819.924934 607.6478 Bcl-2-associated transcription factor 1 OS=Homo sapiens OX=9606 GN=BCLAF1 PE=1 SV=2 6.2 3870 - 454769 - - - 1.7786 - 2.469 0.488 - 154 1 1 0 0.0032 16 0 0 0 - - - - - 6.2989 0.9996 221125_WJC_METTL3_EV_vs_WT_F06.25731.25731.3 0.000913 Nov-84 R.EFASHLQQLQDALNELTEEHSK[136.11].A "sp|Q14980|NUMA1_HUMAN,tr|A0A087WY61|A0A087WY61_HUMAN,tr|F5H4J1|F5H4J1_HUMAN,tr|F5H6Y5|F5H6Y5_HUMAN" 4 2574.2442 2.5 91647 25731 3 2574.23566 859.0887 Nuclear mitotic apparatus protein 1 OS=Homo sapiens OX=9606 GN=NUMA1 PE=1 SV=2 4.56 3870.6 - 262105 - - - -3.3019 - 2.505 0.427 - 89.2 1 2 0 -0.0085 22 0 0 0 1.20E+07 4.82E+06 - - - 5.4754 0.9998 221125_WJC_METTL3_EV_vs_WT_F06.25735.25735.4 6.98E-06 15/126 K.KPDC[160.03]DDWESGLNAMEC[160.03]ALHLEK.N "sp|P02794|FRIH_HUMAN,tr|G3V1D1|G3V1D1_HUMAN,tr|E9PPQ4|E9PPQ4_HUMAN,tr|G3V192|G3V192_HUMAN" 4 2617.1247 2.78 91649 25735 4 2617.135166 655.2885 Ferritin heavy chain OS=Homo sapiens OX=9606 GN=FTH1 PE=1 SV=2 4.29 3871.1 - 213291 - - - 3.9956 - 2.785 0.541 - 132.2 1 2 0 0.0105 22 0 0 0 8.17E+06 2.94E+06 - - - 4.2671 1 221125_WJC_METTL3_EV_vs_WT_F06.25738.25738.4 3.08E-14 33/180 L.FGR[166.11]PHNVQPNWITLGNQLDGIHLLDPDVVAR[166.11].F sp|Q86U44|MTA70_HUMAN 1 3510.8387 0.09 91650 25738 4 3510.841155 878.717 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 5.99 3871.6 - 1.74E+06 - - - 0.6864 - 5.191 0.64 - 468.6 1 1 0 0.0024 31 0 0 0 4.56E+06 4.99E+07 - - - 5.2964 1 221125_WJC_METTL3_EV_vs_WT_F06.25739.25739.3 3.22E-07 14/120 K.TSEQLDQPISAC[160.03]C[160.03]FNHNGNIFAYASSYDWSK.G "sp|P78406|RAE1L_HUMAN,tr|E9PQ57|E9PQ57_HUMAN" 2 3609.5565 1.21 91651 25739 3 3610.546636 1204.1928 mRNA export factor OS=Homo sapiens OX=9606 GN=RAE1 PE=1 SV=1 4.53 3871.7 - 288684 - - - 274.3005 - 3.111 0.705 - 187.1 1 2 0 0.9901 31 0 0 0 1.09E+06 9.02E+05 - - - 8.7369 0.9999 221125_WJC_METTL3_EV_vs_WT_F06.25742.25742.3 8.61E-08 18/64 R.THNLEPYFESFINNLRR.R sp|P04264|K2C1_HUMAN 1 2149.0705 399.32 91653 25742 3 2149.076764 717.3641 "Keratin, type II cytoskeletal 1 OS=Homo sapiens OX=9606 GN=KRT1 PE=1 SV=6" 6.42 3872 - 2.12E+06 - - - 2.9208 - 2.576 0.549 - 351.7 1 2 0 0.0063 17 0 0 0 2.27E+08 5.69E+05 - - - 7.0495 0.9933 221125_WJC_METTL3_EV_vs_WT_F06.25746.25746.4 6.22E-10 26/156 R.K[136.11]IELFGR[166.11]PHNVQPNWITLGNQLDGIHL.L sp|Q86U44|MTA70_HUMAN 1 3126.6846 0.04 91656 25746 4 3126.695066 782.6784 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 6.92 3872.5 - 1.20E+06 - - - 3.3496 - 4.591 0.596 - 411.3 1 1 0 0.0105 27 0 0 0 3.60E+06 1.02E+08 - - - 4.8876 0.9998 221125_WJC_METTL3_EV_vs_WT_F06.25754.25754.4 0.000677 16/240 K.KPGILGDSPLGALQPGAQPANPLLGELPAGGGLPPELPPRR.G "sp|Q8IY67|RAVR1_HUMAN,tr|E9PAU2|E9PAU2_HUMAN,tr|A0A087WZ13|A0A087WZ13_HUMAN" 3 4017.2164 0.79 91660 25754 4 4017.21109 1005.3114 Ribonucleoprotein PTB-binding 1 OS=Homo sapiens OX=9606 GN=RAVER1 PE=1 SV=1 6.18 3873.6 - 347094 - - - -1.3143 - 2.525 0.391 - 42 1 2 0 -0.0053 41 0 0 0 3.98E+06 5.02E+06 - - - 2.8939 0.9998 221125_WJC_METTL3_EV_vs_WT_F06.25755.25755.4 1.01E-05 9/270 R.YSTGSDSASFPHTTPSMC[160.03]LNPDLEGPPLEAYTIQGQYAIPQPDLTK.L "sp|Q15366|PCBP2_HUMAN,tr|H3BSS4|H3BSS4_HUMAN" 2 4994.3266 1.01 91661 25755 4 4994.329553 1249.5889 Poly(rC)-binding protein 2 OS=Homo sapiens OX=9606 GN=PCBP2 PE=1 SV=1 4.1 3873.7 - 550034 - - - 0.5819 - 2.015 0.383 - 12.8 1 2 0 0.0029 46 0 0 0 4.58E+07 4.52E+07 - - - 2.7556 1 221125_WJC_METTL3_EV_vs_WT_F06.25759.25759.3 4.97E-07 22/60 V.RQNLEPLFEQYINNLR.R "sp|P48668|K2C6C_HUMAN,sp|P04259|K2C6B_HUMAN,sp|P13647|K2C5_HUMAN,sp|P02538|K2C6A_HUMAN,tr|F8W0C6|F8W0C6_HUMAN" 5 2046.0647 88.49 91663 25759 3 2046.074021 683.0288 "Keratin, type II cytoskeletal 6C OS=Homo sapiens OX=9606 GN=KRT6C PE=1 SV=3" 6.14 3874.2 - 755172 - - - 4.5688 - 3.996 0.594 - 840.7 1 1 0 0.0093 16 0 0 0 3.29E+07 3.71E+05 - - - 8.7144 0.9997 221125_WJC_METTL3_EV_vs_WT_F06.25777.25777.3 8.29E-05 Nov-72 R.GLLQDDAHPTLVTYADHSK[136.11].L "sp|Q86U44|MTA70_HUMAN,tr|F5H6D8|F5H6D8_HUMAN,tr|H0YFV6|H0YFV6_HUMAN,tr|B4DTN4|B4DTN4_HUMAN" 4 2088.0367 0.25 91672 25777 3 2088.042714 697.0195 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 5.13 3876.5 - 195937 - - - 2.8644 - 2.236 0.428 - 136.5 1 2 0 0.006 19 0 0 0 3.01E+06 1.19E+07 - - - 5.2871 0.9997 221125_WJC_METTL3_EV_vs_WT_F06.25803.25803.4 5.00E-06 20/168 K.EQQEAIEHIDEVQNEIDR[166.11]LNEQASEEILK[136.11].V "sp|Q01105|SET_HUMAN,tr|A0A0C4DFV9|A0A0C4DFV9_HUMAN" 2 3466.6819 0.83 91686 25803 4 3466.679867 867.6777 Protein SET OS=Homo sapiens OX=9606 GN=SET PE=1 SV=3 4.04 3879.7 - 1.09E+06 - - - -0.5781 - 3.431 0.435 - 183.1 1 2 1 -0.002 29 0 0 0 2.02E+07 2.45E+07 - - - 3.3916 1 221125_WJC_METTL3_EV_vs_WT_F06.25817.25817.3 1.54E-08 19/96 K.TSEVQELQNDLDRETSSLQELEAQK.Q "sp|Q9UBC2|EP15R_HUMAN,tr|M0R2S2|M0R2S2_HUMAN,tr|M0R165|M0R165_HUMAN" 3 2889.384 6.16 91694 25817 3 2889.38103 964.1353 Epidermal growth factor receptor substrate 15-like 1 OS=Homo sapiens OX=9606 GN=EPS15L1 PE=1 SV=1 4 3881.4 - 889858 - - - -1.012 - 4.213 0.591 - 329.9 1 2 1 -0.0029 25 0 0 0 1.25E+07 2.02E+06 - - - 8.437 0.9334 221125_WJC_METTL3_EV_vs_WT_F06.25818.25818.4 0.0243 12/168 K.MK[136.11]ETAENYLGHTAK[136.11]NAVITVPAYFNDSQR[166.11].Q "sp|P38646|GRP75_HUMAN,tr|H0Y8K0|H0Y8K0_HUMAN,tr|A0A7I2V2S7|A0A7I2V2S7_HUMAN,tr|A0A7I2V2G2|A0A7I2V2G2_HUMAN,tr|A0A7I2V3F7|A0A7I2V3F7_HUMAN,tr|A0A7I2YQB2|A0A7I2YQB2_HUMAN,tr|D6RCD7|D6RCD7_HUMAN" 7 3293.6349 0.04 91695 25818 4 3293.650648 824.416 "Stress-70 protein, mitochondrial OS=Homo sapiens OX=9606 GN=HSPA9 PE=1 SV=2" 6.51 3881.5 - 376349 - - - 4.7719 - 2.026 0.279 - 51.1 1 2 2 0.0157 29 0 0 0 8.85E+05 2.07E+07 - - - 1.8677 0.9994 221125_WJC_METTL3_EV_vs_WT_F06.25822.25822.3 2.65E-07 18/112 K.MK[136.11]ETAENYLGHTAK[136.11]NAVITVPAYFNDSQR[166.11].Q "sp|P38646|GRP75_HUMAN,tr|H0Y8K0|H0Y8K0_HUMAN,tr|A0A7I2V2S7|A0A7I2V2S7_HUMAN,tr|A0A7I2V2G2|A0A7I2V2G2_HUMAN,tr|A0A7I2V3F7|A0A7I2V3F7_HUMAN,tr|A0A7I2YQB2|A0A7I2YQB2_HUMAN,tr|D6RCD7|D6RCD7_HUMAN" 7 3293.6349 0.001 91697 25822 3 3293.640424 1098.8856 "Stress-70 protein, mitochondrial OS=Homo sapiens OX=9606 GN=HSPA9 PE=1 SV=2" 6.51 3882.1 - 1.36E+06 - - - 1.6678 - 3.301 0.366 - 136.7 1 2 2 0.0055 29 0 0 0 0.00E+00 1.01E+08 - - - 5.3665 0.9999 221125_WJC_METTL3_EV_vs_WT_F06.25826.25826.4 3.85E-10 17/150 R.GEEAHLPPVSDLTVEFDKLNLQNIGR.S "sp|Q86XL3|ANKL2_HUMAN,tr|F5H1D4|F5H1D4_HUMAN" 2 2890.4825 2.81 91699 25826 4 2890.488842 723.6279 Ankyrin repeat and LEM domain-containing protein 2 OS=Homo sapiens OX=9606 GN=ANKLE2 PE=1 SV=4 4.5 3882.6 - 423459 - - - 2.1986 - 3.954 0.579 - 211.4 1 2 1 0.0064 26 0 0 0 8.22E+06 2.92E+06 - - - 4.6975 0.9887 221125_WJC_METTL3_EV_vs_WT_F06.25833.25833.3 1.25E-09 20/84 K.R[166.11]R[166.11]AEQDSTTVAAFASSLVSGLN.S "sp|Q86U44|MTA70_HUMAN,tr|F5H6D8|F5H6D8_HUMAN,tr|H0YFV6|H0YFV6_HUMAN,tr|B4DTN4|B4DTN4_HUMAN" 4 2299.1671 0.01 91702 25833 3 2299.169294 767.3963 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 6.07 3883.5 - 1.20E+07 - - - 0.9421 - 2.817 0.532 - 526.6 1 1 1 0.0022 22 0 0 0 4.12E+06 8.16E+08 - - - 6.9261 1 221125_WJC_METTL3_EV_vs_WT_F06.25834.25834.4 4.00E-09 16/108 R.GLLQDDAHPTLVTYADHSK[136.11].L "sp|Q86U44|MTA70_HUMAN,tr|F5H6D8|F5H6D8_HUMAN,tr|H0YFV6|H0YFV6_HUMAN,tr|B4DTN4|B4DTN4_HUMAN" 4 2088.0367 0 91703 25834 4 2088.033556 523.0165 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 5.13 3883.7 - 419012 - - - -1.5215 - 2.746 0.593 - 224.6 1 2 0 -0.0032 19 0 0 0 4.00E+04 2.69E+07 - - - 4.7283 0.9827 221125_WJC_METTL3_EV_vs_WT_F06.25835.25835.4 2.58E-07 28/198 K.TIGTK[136.11]PVAHIDQFTADMLGSAELAEEVNLNGSGK[136.11].L sp|P50991|TCPD_HUMAN 1 3528.7741 0.28 91704 25835 4 3529.760794 883.2008 T-complex protein 1 subunit delta OS=Homo sapiens OX=9606 GN=CCT4 PE=1 SV=4 4.5 3883.8 - 2.06E+06 - - - 279.6098 - 3.36 0.496 - 255.5 1 2 0 0.9867 34 0 0 0 5.79E+07 2.05E+08 - - - 3.6313 0.9997 221125_WJC_METTL3_EV_vs_WT_F06.25839.25839.3 0.00162 18/100 R.SGPFGQIFRPDNFVFGQSGAGNNWAK.G "sp|P04350|TBB4A_HUMAN,sp|Q9BVA1|TBB2B_HUMAN,sp|P07437|TBB5_HUMAN,sp|Q13885|TBB2A_HUMAN,sp|P68371|TBB4B_HUMAN,tr|Q5ST81|Q5ST81_HUMAN,tr|Q5JP53|Q5JP53_HUMAN,tr|M0QY85|M0QY85_HUMAN,tr|M0QZL7|M0QZL7_HUMAN,tr|M0R278|M0R278_HUMAN,tr|M0R1I1|M0R1I1_HUMAN" 11 2797.3361 0.43 91705 25839 3 2797.32505 933.4526 Tubulin beta-4A chain OS=Homo sapiens OX=9606 GN=TUBB4A PE=1 SV=2 8.46 3884.4 - 451655 - - - -3.9491 - 2.817 0.463 - 207.6 1 2 0 -0.011 26 0 0 0 1.71E+07 4.01E+07 - - - 6.0816 0.9021 221125_WJC_METTL3_EV_vs_WT_F06.25844.25844.4 0.00387 20/198 K.TIGTKPVAHIDQFTADMLGSAELAEEVNLNGSGK.L sp|P50991|TCPD_HUMAN 1 3512.7457 0.29 91708 25844 4 3513.73119 879.1937 T-complex protein 1 subunit delta OS=Homo sapiens OX=9606 GN=CCT4 PE=1 SV=4 4.5 3885 - 1.57E+06 - - - 280.5429 - 2.726 0.397 - 112.9 1 2 0 0.9855 34 0 0 0 5.72E+07 1.99E+08 - - - 2.7076 1 221125_WJC_METTL3_EV_vs_WT_F06.25845.25845.4 2.55E-10 22/108 R.ADLEMQIESLKEELAYLKK.N sp|P02533|K1C14_HUMAN 1 2250.1817 634.06 91709 25845 4 2250.187462 563.5527 "Keratin, type I cytoskeletal 14 OS=Homo sapiens OX=9606 GN=KRT14 PE=1 SV=4" 4.59 3885.2 - 1.04E+06 - - - 2.5447 - 4.125 0.642 - 437.4 1 2 1 0.0057 19 0 0 0 4.16E+07 6.56E+04 - - - 5.2917 0.9883 221125_WJC_METTL3_EV_vs_WT_F06.25850.25850.3 5.60E-05 23/132 K.TIGTK[136.11]PVAHIDQFTADMLGSAELAEEVNLNGSGK[136.11].L sp|P50991|TCPD_HUMAN 1 3528.7741 0.23 91712 25850 3 3529.759327 1177.2653 T-complex protein 1 subunit delta OS=Homo sapiens OX=9606 GN=CCT4 PE=1 SV=4 4.5 3885.8 - 1.22E+06 - - - 279.1941 - 3.121 0.536 - 264.5 1 2 0 0.9852 34 0 0 0 7.05E+06 3.10E+07 - - - 6.8614 1 221125_WJC_METTL3_EV_vs_WT_F06.25858.25858.4 1.97E-07 16/120 R.QVLDLEDLVFTQGSHFMANKR.C "sp|O75643|U520_HUMAN,tr|A0A494C1A5|A0A494C1A5_HUMAN" 2 2447.2267 0.7 91716 25858 4 2447.231862 612.814 U5 small nuclear ribonucleoprotein 200 kDa helicase OS=Homo sapiens OX=9606 GN=SNRNP200 PE=1 SV=2 5.38 3886.9 - 249407 - - - 2.0975 - 2.715 0.521 - 122.8 1 2 0 0.0051 21 0 0 0 2.28E+06 3.27E+06 - - - 4.0896 0.9998 221125_WJC_METTL3_EV_vs_WT_F06.25859.25859.4 0.000102 14/120 R.HREDIEDYISLFPLDDVQPSK.L "sp|O75448|MED24_HUMAN,tr|B9TX62|B9TX62_HUMAN,tr|F5GY88|F5GY88_HUMAN,tr|H0YEG1|H0YEG1_HUMAN,tr|A0A0B4J1W0|A0A0B4J1W0_HUMAN" 5 2515.2231 0.36 91717 25859 4 2515.227484 629.813 Mediator of RNA polymerase II transcription subunit 24 OS=Homo sapiens OX=9606 GN=MED24 PE=1 SV=1 4.23 3887 - 209135 - - - 1.7493 - 2.445 0.492 - 134.3 1 2 1 0.0044 21 0 0 0 2.78E+06 7.74E+06 - - - 3.8028 1 221125_WJC_METTL3_EV_vs_WT_F06.25860.25860.3 1.67E-07 24/100 R.SGPFGQIFR[166.11]PDNFVFGQSGAGNNWAK[136.11].G "sp|P04350|TBB4A_HUMAN,sp|Q9BVA1|TBB2B_HUMAN,sp|P07437|TBB5_HUMAN,sp|Q13885|TBB2A_HUMAN,sp|P68371|TBB4B_HUMAN,tr|Q5ST81|Q5ST81_HUMAN,tr|Q5JP53|Q5JP53_HUMAN,tr|M0QY85|M0QY85_HUMAN,tr|M0QZL7|M0QZL7_HUMAN,tr|M0R278|M0R278_HUMAN,tr|M0R1I1|M0R1I1_HUMAN" 11 2815.3586 0.42 91718 25860 3 2815.361383 939.4601 Tubulin beta-4A chain OS=Homo sapiens OX=9606 GN=TUBB4A PE=1 SV=2 8.46 3887.1 - 776841 - - - 1.0002 - 4.721 0.623 - 511.5 1 2 0 0.0028 26 0 0 0 1.71E+07 4.07E+07 - - - 9.0557 0.9997 221125_WJC_METTL3_EV_vs_WT_F06.25866.25866.3 0.000105 10/112 K.MK[136.11]ETAENYLGHTAKNAVITVPAYFNDSQR.Q "sp|P38646|GRP75_HUMAN,tr|H0Y8K0|H0Y8K0_HUMAN,tr|A0A7I2V2S7|A0A7I2V2S7_HUMAN,tr|A0A7I2V2G2|A0A7I2V2G2_HUMAN,tr|A0A7I2V3F7|A0A7I2V3F7_HUMAN,tr|A0A7I2YQB2|A0A7I2YQB2_HUMAN,tr|D6RCD7|D6RCD7_HUMAN" 7 3275.6125 - 91722 25866 3 3275.609378 1092.8781 "Stress-70 protein, mitochondrial OS=Homo sapiens OX=9606 GN=HSPA9 PE=1 SV=2" 6.51 3887.9 - 430232 - - - -0.9412 - 2.288 0.481 - 28.6 1 2 2 -0.0031 29 0 0 0 - - - - - 5.806 1 221125_WJC_METTL3_EV_vs_WT_F06.25869.25869.4 1.03E-07 14/120 R.R[166.11]DEQILAQLLPLLHGNVNGSK[136.11].V sp|Q13111|CAF1A_HUMAN 1 2332.2982 1.02 91725 25869 4 2332.301808 584.0818 Chromatin assembly factor 1 subunit A OS=Homo sapiens OX=9606 GN=CHAF1A PE=1 SV=3 6.75 3888.3 - 213395 - - - 1.5474 - 2.887 0.517 - 120.4 1 2 0 0.0036 21 0 0 0 7.28E+06 7.11E+06 - - - 4.0755 1 221125_WJC_METTL3_EV_vs_WT_F06.25872.25872.4 6.10E-05 25/180 R.VATDASFTVQSAFLGNSVLGHLENMHPDNSK.A "sp|Q8IWZ3|ANKH1_HUMAN,tr|A0A0A0MQZ8|A0A0A0MQZ8_HUMAN,tr|H0Y472|H0Y472_HUMAN,tr|H0Y7Y3|H0Y7Y3_HUMAN,tr|H0Y4P6|H0Y4P6_HUMAN,tr|H7C0V5|H7C0V5_HUMAN,tr|H0Y785|H0Y785_HUMAN" 7 3285.5724 1.45 91726 25872 4 3285.571695 822.4004 Ankyrin repeat and KH domain-containing protein 1 OS=Homo sapiens OX=9606 GN=ANKHD1 PE=1 SV=1 5.21 3888.7 - 5.75E+06 - - - -0.2271 - 4.201 0.507 - 299.4 1 2 0 -0.0007 31 0 0 0 1.51E+08 1.04E+08 - - - 4.075 1 221125_WJC_METTL3_EV_vs_WT_F06.25888.25888.3 3.09E-08 15/84 K.EKPYFPIPEEYTFIQNVPLEDR.V "sp|Q00839|HNRPU_HUMAN,tr|A0A1W2PQL0|A0A1W2PQL0_HUMAN,tr|A0A1W2PPL4|A0A1W2PPL4_HUMAN,tr|A0A1W2PQ74|A0A1W2PQ74_HUMAN,tr|Q5RI18|Q5RI18_HUMAN,tr|A0A1W2PP35|A0A1W2PP35_HUMAN,tr|A0A1W2PPS1|A0A1W2PPS1_HUMAN,tr|A0A1W2PRZ7|A0A1W2PRZ7_HUMAN,tr|A0A1W2PPH7|A0A1W2PPH7_HUMAN,tr|A0A1W2PP34|A0A1W2PP34_HUMAN,tr|A0A1X7SBS1|A0A1X7SBS1_HUMAN" 11 2723.3483 1.15 91734 25888 3 2723.344086 908.79 Heterogeneous nuclear ribonucleoprotein U OS=Homo sapiens OX=9606 GN=HNRNPU PE=1 SV=6 4.25 3890.9 - 593408 - - - -1.5415 - 2.935 0.507 - 183.5 1 2 0 -0.0042 22 0 0 0 9.86E+07 8.58E+07 - - - 6.7441 0.9984 221125_WJC_METTL3_EV_vs_WT_F06.25890.25890.4 8.88E-14 37/264 S.SLVGQQFGAVGVAGSSLTSFGTETSNSGTLPQSSAVGSAFTQDTR.S "sp|Q8ND56|LS14A_HUMAN,tr|A0A140TA76|A0A140TA76_HUMAN,tr|K7EMZ9|K7EMZ9_HUMAN" 3 4391.1153 0.92 91735 25890 4 4391.118082 1098.7861 Protein LSM14 homolog A OS=Homo sapiens OX=9606 GN=LSM14A PE=1 SV=3 4.37 3891.1 - 8.55E+06 - - - 0.6265 - 6.383 0.593 - 451.4 1 1 0 0.0028 45 0 0 0 2.26E+08 2.45E+08 - - - 4.9096 1 221125_WJC_METTL3_EV_vs_WT_F06.25894.25894.3 2.25E-11 28/176 S.SLVGQQFGAVGVAGSSLTSFGTETSNSGTLPQSSAVGSAFTQDTR[166.11].S "sp|Q8ND56|LS14A_HUMAN,tr|A0A140TA76|A0A140TA76_HUMAN,tr|K7EMZ9|K7EMZ9_HUMAN" 3 4401.1236 1.08 91737 25894 3 4401.120962 1468.0485 Protein LSM14 homolog A OS=Homo sapiens OX=9606 GN=LSM14A PE=1 SV=3 4.37 3891.6 - 875325 - - - -0.5996 - 4.158 0.643 - 329.4 1 1 0 -0.0026 45 0 0 0 2.47E+07 2.28E+07 - - - 8.9866 1 221125_WJC_METTL3_EV_vs_WT_F06.25895.25895.3 7.47E-08 17/84 K.EK[136.11]PYFPIPEEYTFIQNVPLEDR[166.11].V "sp|Q00839|HNRPU_HUMAN,tr|A0A1W2PQL0|A0A1W2PQL0_HUMAN,tr|A0A1W2PPL4|A0A1W2PPL4_HUMAN,tr|A0A1W2PQ74|A0A1W2PQ74_HUMAN,tr|Q5RI18|Q5RI18_HUMAN,tr|A0A1W2PP35|A0A1W2PP35_HUMAN,tr|A0A1W2PPS1|A0A1W2PPS1_HUMAN,tr|A0A1W2PRZ7|A0A1W2PRZ7_HUMAN,tr|A0A1W2PPH7|A0A1W2PPH7_HUMAN,tr|A0A1W2PP34|A0A1W2PP34_HUMAN,tr|A0A1X7SBS1|A0A1X7SBS1_HUMAN" 11 2741.3708 1.16 91738 25895 3 2741.364961 914.7975 Heterogeneous nuclear ribonucleoprotein U OS=Homo sapiens OX=9606 GN=HNRNPU PE=1 SV=6 4.25 3891.8 - 809188 - - - -2.1132 - 3.304 0.547 - 181.7 1 2 0 -0.0058 22 0 0 0 9.86E+07 8.50E+07 - - - 7.4704 1 221125_WJC_METTL3_EV_vs_WT_F06.25901.25901.4 3.40E-13 38/264 S.SLVGQQFGAVGVAGSSLTSFGTETSNSGTLPQSSAVGSAFTQDTR[166.11].S "sp|Q8ND56|LS14A_HUMAN,tr|A0A140TA76|A0A140TA76_HUMAN,tr|K7EMZ9|K7EMZ9_HUMAN" 3 4401.1236 0.93 91742 25901 4 4401.12004 1101.2882 Protein LSM14 homolog A OS=Homo sapiens OX=9606 GN=LSM14A PE=1 SV=3 4.37 3892.6 - 1.06E+07 - - - -0.8091 - 6.003 0.617 - 462.7 1 1 0 -0.0036 45 0 0 0 2.27E+08 2.45E+08 - - - 5.101 0.9916 221125_WJC_METTL3_EV_vs_WT_F06.25903.25903.3 3.69E-08 13/76 Y.YNTIDDLKDQIVDLTVGNNK.T sp|P35527|K1C9_HUMAN 1 2277.1489 11.08 91744 25903 3 2277.1496 760.0569 "Keratin, type I cytoskeletal 9 OS=Homo sapiens OX=9606 GN=KRT9 PE=1 SV=3" 4.14 3892.8 - 867185 - - - 0.3267 - 2.818 0.556 - 207.9 1 1 1 0.0007 20 0 0 0 1.10E+08 9.94E+06 - - - 7.2521 0.9999 221125_WJC_METTL3_EV_vs_WT_F06.25904.25904.4 1.93E-08 26/150 R.GHNC[160.03]PKPVLNFYEANFPANVMDVIAR.Q "sp|P17844|DDX5_HUMAN,tr|A0A7I2V507|A0A7I2V507_HUMAN,tr|J3KTA4|J3KTA4_HUMAN,tr|J3KTQ4|J3KTQ4_HUMAN,tr|A0A7I2V2S0|A0A7I2V2S0_HUMAN,tr|J3QRQ7|J3QRQ7_HUMAN" 6 2972.4426 1.26 91745 25904 4 2972.430076 744.1179 Probable ATP-dependent RNA helicase DDX5 OS=Homo sapiens OX=9606 GN=DDX5 PE=1 SV=1 6.74 3893 - 854028 - - - -4.1976 - 3.61 0.601 - 384.9 1 2 0 -0.0125 26 0 0 0 3.54E+07 2.80E+07 - - - 4.8586 0.9231 221125_WJC_METTL3_EV_vs_WT_F06.25913.25913.3 2.16E-07 23/88 K.R[166.11]R[166.11]AEQDSTTVAAFASSLVSGLNS.S "sp|Q86U44|MTA70_HUMAN,tr|F5H6D8|F5H6D8_HUMAN,tr|H0YFV6|H0YFV6_HUMAN,tr|B4DTN4|B4DTN4_HUMAN" 4 2386.1992 0 91749 25913 3 2386.190208 796.407 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 6.07 3894.1 - 1.58E+06 - - - -3.7499 - 3.685 0.455 - 606.3 1 1 1 -0.0089 23 0 0 0 1.53E+05 6.32E+07 - - - 6.6701 1 221125_WJC_METTL3_EV_vs_WT_F06.25928.25928.4 3.19E-13 15/120 K.NPDDPDMVDVFMDHLDIDHNK.K sp|P20930|FILA_HUMAN 1 2481.0577 44.63 91755 25928 4 2481.054476 621.2717 Filaggrin OS=Homo sapiens OX=9606 GN=FLG PE=1 SV=3 3.99 3896 - 419457 - - - -1.2894 - 3.383 0.722 - 188.4 1 2 0 -0.0032 21 0 0 0 1.37E+07 3.06E+05 - - - 5.9124 0.9886 221125_WJC_METTL3_EV_vs_WT_F06.25943.25943.4 2.64E-06 15/120 N.VGTRPINLEPIFQGYIDSLKR.Y sp|P35908|K22E_HUMAN 1 2415.3274 50.63 91761 25943 4 2415.333996 604.8391 "Keratin, type II cytoskeletal 2 epidermal OS=Homo sapiens OX=9606 GN=KRT2 PE=1 SV=2" 8.56 3897.8 - 302945 - - - 2.7185 - 2.617 0.496 - 152 1 1 0 0.0066 21 0 0 0 1.79E+07 3.53E+05 - - - 3.8594 1 221125_WJC_METTL3_EV_vs_WT_F06.25952.25952.4 3.00E-05 17/120 K.SADGVIVSGVKDVDDFFEHER.T "sp|Q9UNH7|SNX6_HUMAN,tr|A0A0A0MRI2|A0A0A0MRI2_HUMAN,tr|G3V5X9|G3V5X9_HUMAN" 3 2320.0972 1.89 91765 25952 4 2320.099138 581.0316 Sorting nexin-6 OS=Homo sapiens OX=9606 GN=SNX6 PE=1 SV=1 4.23 3899 - 439494 - - - 0.8547 - 3.331 0.627 - 214.8 1 2 1 0.002 21 0 0 0 1.89E+07 1.00E+07 - - - 5.0807 0.9997 221125_WJC_METTL3_EV_vs_WT_F06.25955.25955.3 1.18E-10 15/68 K.YVHYEIDAC[160.03]MDSEAPGSK[136.11].D "sp|Q86U44|MTA70_HUMAN,tr|H0YFV6|H0YFV6_HUMAN" 2 2078.8805 0 91766 25955 3 2079.882183 693.9674 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 4.31 3899.4 - 553785 - - - 481.8416 - 3.078 0.65 - 234.9 1 2 0 1.0017 18 0 0 0 1.31E+05 3.89E+07 - - - 8.309 1 221125_WJC_METTL3_EV_vs_WT_F06.25959.25959.4 3.91E-10 21/120 K.SADGVIVSGVK[136.11]DVDDFFEHER[166.11].T "sp|Q9UNH7|SNX6_HUMAN,tr|A0A0A0MRI2|A0A0A0MRI2_HUMAN,tr|G3V5X9|G3V5X9_HUMAN" 3 2338.1196 1.89 91768 25959 4 2338.124058 585.5372 Sorting nexin-6 OS=Homo sapiens OX=9606 GN=SNX6 PE=1 SV=1 4.23 3899.8 - 273275 - - - 1.896 - 4.319 0.635 - 376.6 1 2 1 0.0044 21 0 0 0 1.89E+07 1.00E+07 - - - 5.2355 1 221125_WJC_METTL3_EV_vs_WT_F06.25964.25964.4 2.43E-13 25/150 R.GHNC[160.03]PK[136.11]PVLNFYEANFPANVMDVIAR[166.11].Q "sp|P17844|DDX5_HUMAN,tr|A0A7I2V507|A0A7I2V507_HUMAN,tr|J3KTA4|J3KTA4_HUMAN,tr|J3KTQ4|J3KTQ4_HUMAN,tr|A0A7I2V2S0|A0A7I2V2S0_HUMAN,tr|J3QRQ7|J3QRQ7_HUMAN" 6 2990.465 1.31 91770 25964 4 2990.471125 748.6235 Probable ATP-dependent RNA helicase DDX5 OS=Homo sapiens OX=9606 GN=DDX5 PE=1 SV=1 6.74 3900.5 - 649260 - - - 2.0405 - 3.859 0.698 - 518.7 1 2 0 0.0061 26 0 0 0 4.09E+07 3.12E+07 - - - 5.7257 0.9961 221125_WJC_METTL3_EV_vs_WT_F06.25965.25965.4 6.24E-07 20/126 M.NVGTRPINLEPIFQGYIDSLKR.Y sp|P35908|K22E_HUMAN 1 2529.3704 20.61 91771 25965 4 2529.374641 633.3499 "Keratin, type II cytoskeletal 2 epidermal OS=Homo sapiens OX=9606 GN=KRT2 PE=1 SV=2" 8.59 3900.6 - 465134 - - - 1.6937 - 3.499 0.524 - 181.2 1 1 0 0.0043 22 0 0 0 6.37E+07 3.09E+06 - - - 4.1955 1 221125_WJC_METTL3_EV_vs_WT_F06.25969.25969.4 1.18E-11 36/222 K.QEPLHSTSYAVNILENISSSESSKPIELDGLPSDQFAK.G "sp|Q2KHR3|QSER1_HUMAN,tr|A0A3B3IRW6|A0A3B3IRW6_HUMAN,tr|H0YCQ7|H0YCQ7_HUMAN" 3 4130.0332 2.7 91773 25969 4 4130.042276 1033.5156 Glutamine and serine-rich protein 1 OS=Homo sapiens OX=9606 GN=QSER1 PE=1 SV=3 4.35 3901.1 - 732386 - - - 2.206 - 5.757 0.658 - 453.9 1 2 0 0.0091 38 0 0 0 3.32E+07 1.23E+07 - - - 5.4611 0.8782 221125_WJC_METTL3_EV_vs_WT_F06.25973.25973.3 5.49E-10 19/72 K.NKLNDLEDALQQAKEDLAR.L sp|P04264|K2C1_HUMAN 1 2183.1182 7.07 91776 25973 3 2184.105211 728.7134 "Keratin, type II cytoskeletal 1 OS=Homo sapiens OX=9606 GN=KRT1 PE=1 SV=6" 4.44 3901.6 - 311500 - - - 452.0992 - 4.099 0.551 - 566.6 1 2 2 0.987 19 0 0 0 2.38E+06 3.36E+05 - - - 7.8756 0.9997 221125_WJC_METTL3_EV_vs_WT_F06.25977.25977.3 6.08E-06 9/124 R.GGGGSFGYSYGGGSGGGFSASSLGGGFGGGSR.G sp|P35527|K1C9_HUMAN 1 2704.1538 999 91778 25977 3 2704.164686 902.3919 "Keratin, type I cytoskeletal 9 OS=Homo sapiens OX=9606 GN=KRT9 PE=1 SV=3" 8.59 3902.2 - 202642 - - - 4.0127 - 2.016 0.561 - 44.8 1 2 0 0.0109 32 0 0 0 1.66E+07 0.00E+00 - - - 6.4046 1 221125_WJC_METTL3_EV_vs_WT_F06.25993.25993.4 2.09E-16 34/216 R.QVFAENKDEIALVLFGTDGTDNPLSGGDQYQNITVHR.H "sp|P13010|XRCC5_HUMAN,tr|C9JZ81|C9JZ81_HUMAN" 2 4060.9767 0.89 91788 25993 4 4060.980552 1016.2514 X-ray repair cross-complementing protein 5 OS=Homo sapiens OX=9606 GN=XRCC5 PE=1 SV=3 4.23 3904.2 - 1.23E+06 - - - 0.9601 - 6.126 0.696 - 580.1 1 2 1 0.0039 37 0 0 0 4.14E+07 4.64E+07 - - - 5.8143 0.9995 221125_WJC_METTL3_EV_vs_WT_F06.26001.26001.4 4.61E-11 26/222 K.QEPLHSTSYAVNILENISSSESSK[136.11]PIELDGLPSDQFAK[136.11].G "sp|Q2KHR3|QSER1_HUMAN,tr|A0A3B3IRW6|A0A3B3IRW6_HUMAN,tr|H0YCQ7|H0YCQ7_HUMAN" 3 4146.0616 2.66 91792 26001 4 4147.057569 1037.5227 Glutamine and serine-rich protein 1 OS=Homo sapiens OX=9606 GN=QSER1 PE=1 SV=3 4.35 3905.2 - 650116 - - - 240.2289 - 4.758 0.635 - 190 1 2 0 0.996 38 0 0 0 3.28E+07 1.23E+07 - - - 4.932 0.8821 221125_WJC_METTL3_EV_vs_WT_F06.26015.26015.3 1.33E-09 29/120 K.DHTPSQELALTQSVGGDSSADR[166.11]LFPPQWIC[160.03]C[160.03].D sp|Q86U44|MTA70_HUMAN 1 3481.5906 0 91799 26015 3 3482.593337 1161.5375 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 4.22 3907.1 - 2.11E+06 - - - 288.0043 - 3.575 0.611 - 417.7 1 1 1 1.0027 31 0 0 0 2.70E+05 5.43E+07 - - - 8.0052 1 221125_WJC_METTL3_EV_vs_WT_F06.26022.26022.3 1.45E-09 14/72 R.YVASYLLAALGGNSSPSAK.D sp|P05387|RLA2_HUMAN 1 1867.968 1.26 91803 26022 3 1867.971385 623.6633 60S acidic ribosomal protein P2 OS=Homo sapiens OX=9606 GN=RPLP2 PE=1 SV=1 8.5 3908 - 253984 - - - 1.8234 - 2.8 0.608 - 196.7 1 2 0 0.0034 19 0 0 0 9.50E+06 7.53E+06 - - - 7.8472 0.9992 221125_WJC_METTL3_EV_vs_WT_F06.26023.26023.3 3.62E-07 14/72 R.YVASYLLAALGGNSSPSAK[136.11].D sp|P05387|RLA2_HUMAN 1 1875.9822 1.26 91804 26023 3 1875.992248 626.3347 60S acidic ribosomal protein P2 OS=Homo sapiens OX=9606 GN=RPLP2 PE=1 SV=1 8.5 3908.2 - 191696 - - - 5.3673 - 2.446 0.488 - 146.6 1 2 0 0.0101 19 0 0 0 9.50E+06 7.53E+06 - - - 6.1754 0.9997 221125_WJC_METTL3_EV_vs_WT_F06.26039.26039.3 1.71E-05 Nov-72 R.GLLQDDAHPTLVTYADHSK[136.11].L "sp|Q86U44|MTA70_HUMAN,tr|F5H6D8|F5H6D8_HUMAN,tr|H0YFV6|H0YFV6_HUMAN,tr|B4DTN4|B4DTN4_HUMAN" 4 2088.0367 0.11 91812 26039 3 2088.029569 697.0195 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 5.13 3910.4 - 608374 - - - -3.431 - 2.499 0.449 - 137.2 1 2 0 -0.0072 19 0 0 0 1.48E+06 1.35E+07 - - - 5.7941 1 221125_WJC_METTL3_EV_vs_WT_F06.26041.26041.3 9.14E-06 16/100 R.SSGTASSVAFTPLQGLEIVNPQAAEK.K "sp|Q8WWY3|PRP31_HUMAN,tr|E7EVX8|E7EVX8_HUMAN" 2 2601.3286 3.27 91813 26041 3 2601.329703 868.1168 U4\U6 small nuclear ribonucleoprotein Prp31 OS=Homo sapiens OX=9606 GN=PRPF31 PE=1 SV=2 4.53 3910.6 - 601617 - - - 0.4194 - 2.914 0.505 - 177.8 1 2 0 0.0011 26 0 0 0 9.89E+06 3.02E+06 - - - 6.6305 1 221125_WJC_METTL3_EV_vs_WT_F06.26046.26046.3 9.83E-09 24/136 R.K[136.11]IELFGR[166.11]PHNVQPNWITLGNQLDGIHLLDPDVVAR[166.11].F sp|Q86U44|MTA70_HUMAN 1 4002.1586 0.001 91814 26046 3 4002.145358 1335.0602 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 6.01 3911.4 - 0 - - - -3.316 - 3.642 0.684 - 180.7 1 2 0 -0.0133 35 0 0 0 0.00E+00 1.44E+08 - - - 9.1359 0.992 221125_WJC_METTL3_EV_vs_WT_F06.26053.26053.2 0.000963 24-Nov L.DGIHLLDPDVVAR[166.11].F sp|Q86U44|MTA70_HUMAN 1 1428.76 0.15 91816 26053 2 1428.759932 715.3873 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 4.41 3912.3 - 943022 - - - -0.0812 - 2.387 0.459 - 302.8 1 1 0 -0.0001 13 0 0 0 8.09E+06 5.39E+07 - - - 4.6641 0.9996 221125_WJC_METTL3_EV_vs_WT_F06.26064.26064.4 6.59E-05 13/108 R.GLLQDDAHPTLVTYADHSK[136.11].L "sp|Q86U44|MTA70_HUMAN,tr|F5H6D8|F5H6D8_HUMAN,tr|H0YFV6|H0YFV6_HUMAN,tr|B4DTN4|B4DTN4_HUMAN" 4 2088.0367 0.001 91818 26064 4 2088.031055 523.0165 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 5.13 3914 - 590232 - - - -2.7193 - 2.383 0.396 - 68.1 1 2 0 -0.0057 19 0 0 0 0.00E+00 5.82E+07 - - - 2.965 1 221125_WJC_METTL3_EV_vs_WT_F06.26068.26068.4 2.72E-08 32/198 K.DHTPSQELALTQSVGGDSSADR[166.11]LFPPQWIC[160.03]C[160.03]DIR[166.11].Y sp|Q86U44|MTA70_HUMAN 1 3875.811 0 91819 26068 4 3875.804268 969.96 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 4.35 3914.6 - 5.62E+06 - - - -1.74 - 4.345 0.642 - 464.1 1 2 1 -0.0067 34 0 0 0 6.48E+05 3.34E+08 - - - 5.2502 0.9947 221125_WJC_METTL3_EV_vs_WT_F06.26129.26129.3 0.000265 26/124 R.AEQDSTTVAAFASSLVSGLNSSASEPAK[136.11]EPAK[136.11].K "sp|Q86U44|MTA70_HUMAN,tr|F5H6D8|F5H6D8_HUMAN,tr|H0YFV6|H0YFV6_HUMAN,tr|B4DTN4|B4DTN4_HUMAN" 4 3165.5648 0.001 91830 26129 3 3166.558061 1056.1956 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 4.41 3923.8 - 2.30E+06 - - - 313.7604 - 4.923 0.586 - 492.4 1 2 1 0.9932 32 0 0 0 0.00E+00 2.80E+07 - - - 8.4652 0.9993 221125_WJC_METTL3_EV_vs_WT_F06.26139.26139.3 0.00178 13/60 R.QNLEPLFEQYINNLRR.Q "sp|P48668|K2C6C_HUMAN,sp|P04259|K2C6B_HUMAN,sp|P13647|K2C5_HUMAN,sp|P02538|K2C6A_HUMAN,tr|F8W0C6|F8W0C6_HUMAN" 5 2046.0647 565.25 91833 26139 3 2046.059767 683.0288 "Keratin, type II cytoskeletal 6C OS=Homo sapiens OX=9606 GN=KRT6C PE=1 SV=3" 6.14 3925.1 - 2.14E+06 - - - -2.3978 - 2.211 0.331 - 131.1 1 2 0 -0.0049 16 0 0 0 6.38E+07 1.13E+05 - - - 4.2648 1 221125_WJC_METTL3_EV_vs_WT_F06.26158.26158.4 3.11E-13 32/258 R.FGGFGGPGGVGGLGGPGGFGPGGYPGGIHEVSVNQSLLQPLNVK.V sp|P35908|K22E_HUMAN 1 4091.0653 148.34 91839 26158 4 4091.059968 1023.7736 "Keratin, type II cytoskeletal 2 epidermal OS=Homo sapiens OX=9606 GN=KRT2 PE=1 SV=2" 6.75 3927.8 - 3.96E+06 - - - -1.3153 - 4.958 0.616 - 217.7 1 2 0 -0.0054 44 0 0 0 5.20E+07 3.51E+05 - - - 5.0398 1 221125_WJC_METTL3_EV_vs_WT_F06.26163.26163.4 7.88E-13 21/258 R.NEPDVYETSDLPEDDQAEFDAEELTSTSVEHIIVNPNAAYDKFK.D "sp|Q13561|DCTN2_HUMAN,tr|F8W1I6|F8W1I6_HUMAN,tr|A0A7I2V4H4|A0A7I2V4H4_HUMAN,tr|A0A7I2V390|A0A7I2V390_HUMAN,tr|A0A7I2V2Z2|A0A7I2V2Z2_HUMAN,tr|F8VRV7|F8VRV7_HUMAN" 6 4984.2574 4.73 91842 26163 4 4984.25288 1247.0716 Dynactin subunit 2 OS=Homo sapiens OX=9606 GN=DCTN2 PE=1 SV=4 3.79 3928.4 - 1.42E+06 - - - -0.9117 - 4.47 0.755 - 190.4 1 2 1 -0.0045 44 0 0 0 1.69E+07 3.57E+06 - - - 6.2205 0.9999 221125_WJC_METTL3_EV_vs_WT_F06.26166.26166.3 3.31E-09 19/112 K.MK[136.11]EIAEAYLGYPVTNAVITVPAYFNDSQR[166.11].Q "sp|P0DMV8|HS71A_HUMAN,sp|P0DMV9|HS71B_HUMAN,tr|A0A0G2JIW1|A0A0G2JIW1_HUMAN" 3 3277.6448 0.02 91843 26166 3 3277.640748 1093.5556 Heat shock 70 kDa protein 1A OS=Homo sapiens OX=9606 GN=HSPA1A PE=1 SV=1 4.68 3928.8 - 1.81E+06 - - - -1.2427 - 3.843 0.57 - 158.6 1 2 1 -0.0041 29 0 0 0 7.20E+05 3.74E+07 - - - 7.9911 0.9999 221125_WJC_METTL3_EV_vs_WT_F06.26167.26167.3 3.96E-10 17/76 K.HAASDVDLEIESLLNQQSTK[136.11].E "sp|Q86U44|MTA70_HUMAN,tr|F5H6D8|F5H6D8_HUMAN,tr|H0YFV6|H0YFV6_HUMAN,tr|B4DTN4|B4DTN4_HUMAN" 4 2205.1005 0.06 91844 26167 3 2205.09125 736.0408 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 4.31 3929 - 930206 - - - -4.1749 - 3.76 0.583 - 338 1 2 0 -0.0092 20 0 0 0 2.72E+06 4.46E+07 - - - 8.2504 1 221125_WJC_METTL3_EV_vs_WT_F06.26172.26172.4 9.80E-14 29/174 R.DYLGDFIEHYAQLGPSQPPDLAQAQDEPR[166.11]R[166.11].A sp|Q00577|PURA_HUMAN 1 3445.6442 2.44 91846 26172 4 3445.639655 862.4183 Transcriptional activator protein Pur-alpha OS=Homo sapiens OX=9606 GN=PURA PE=1 SV=2 4.23 3929.7 - 1.23E+06 - - - -1.3153 - 4.798 0.702 - 312.1 1 2 0 -0.0045 30 0 0 0 3.22E+07 1.32E+07 - - - 5.8148 1 221125_WJC_METTL3_EV_vs_WT_F06.26173.26173.4 2.84E-10 33/162 R.PHNVQPNWITLGNQLDGIHLLDPDVVAR[166.11].F sp|Q86U44|MTA70_HUMAN 1 3140.6395 0.02 91847 26173 4 3140.649664 786.1671 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 5.14 3929.8 - 1.41E+06 - - - 3.2407 - 4.762 0.65 - 504.2 1 1 0 0.0102 28 0 0 0 2.38E+07 1.02E+09 - - - 5.3653 0.9999 221125_WJC_METTL3_EV_vs_WT_F06.26174.26174.4 3.50E-06 31/210 K.ENKVPEELQDKEFAAVLQDEPLQPLALEPLTEEEQR.N sp|O75420|GGYF1_HUMAN 1 4174.0958 999 91848 26174 4 4174.090047 1044.5312 GRB10-interacting GYF protein 1 OS=Homo sapiens OX=9606 GN=GIGYF1 PE=1 SV=2 3.99 3929.9 - 1.39E+06 - - - -1.3699 - 4.381 0.608 - 339.5 1 2 2 -0.0057 36 0 0 0 1.80E+07 0.00E+00 - - - 4.9519 1 221125_WJC_METTL3_EV_vs_WT_F06.26181.26181.4 4.69E-14 36/174 R.DYLGDFIEHYAQLGPSQPPDLAQAQDEPRR.A sp|Q00577|PURA_HUMAN 1 3425.6276 2.44 91851 26181 4 3425.624021 857.4142 Transcriptional activator protein Pur-alpha OS=Homo sapiens OX=9606 GN=PURA PE=1 SV=2 4.23 3930.9 - 1.43E+06 - - - -1.0585 - 5.94 0.654 - 611.6 1 2 0 -0.0036 30 0 0 0 3.22E+07 1.32E+07 - - - 5.4626 1 221125_WJC_METTL3_EV_vs_WT_F06.26194.26194.3 1.04E-06 17/60 R.NVQALEIELQSQLALK.Q "sp|P13645|K1C10_HUMAN,tr|A0A1B0GVI3|A0A1B0GVI3_HUMAN" 2 1796.0044 11.76 91855 26194 3 1796.001629 599.6754 "Keratin, type I cytoskeletal 10 OS=Homo sapiens OX=9606 GN=KRT10 PE=1 SV=6" 4.53 3932.5 - 878390 - - - -1.5228 - 3.266 0.526 - 524 1 2 0 -0.0027 16 0 0 0 1.11E+07 9.41E+05 - - - 7.4405 1 221125_WJC_METTL3_EV_vs_WT_F06.26196.26196.3 8.95E-08 18/68 K.YVHYEIDAC[160.03]MDSEAPGSK[136.11].D "sp|Q86U44|MTA70_HUMAN,tr|H0YFV6|H0YFV6_HUMAN" 2 2078.8805 0.01 91856 26196 3 2078.877459 693.9674 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 4.31 3932.7 - 1.05E+06 - - - -1.459 - 3.31 0.639 - 378.9 1 2 0 -0.003 18 0 0 0 4.71E+05 5.98E+07 - - - 8.6439 1 221125_WJC_METTL3_EV_vs_WT_F06.26198.26198.3 1.25E-12 35/108 R.PHNVQPNWITLGNQLDGIHLLDPDVVAR[166.11].F sp|Q86U44|MTA70_HUMAN 1 3140.6395 0 91857 26198 3 3141.635683 1047.8871 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 5.14 3932.9 - 3.83E+06 - - - 317.1956 - 4.844 0.628 - 594.5 1 1 0 0.9962 28 0 0 0 2.92E+05 8.77E+07 - - - 8.8954 0.9998 221125_WJC_METTL3_EV_vs_WT_F06.26204.26204.4 8.91E-06 14/102 K.NMPLQHLLEQIKELEKER.E sp|P15924|DESP_HUMAN 1 2247.2045 21.32 91861 26204 4 2247.204727 562.8084 Desmoplakin OS=Homo sapiens OX=9606 GN=DSP PE=1 SV=3 5.57 3933.7 - 422980 - - - 0.0845 - 2.906 0.483 - 106.3 1 2 2 0.0002 18 0 0 0 8.36E+06 3.92E+05 - - - 3.7954 0.9893 221125_WJC_METTL3_EV_vs_WT_F06.26215.26215.3 5.18E-07 16/72 H.AASDVDLEIESLLNQQSTK[136.11].E "sp|Q86U44|MTA70_HUMAN,tr|F5H6D8|F5H6D8_HUMAN,tr|H0YFV6|H0YFV6_HUMAN,tr|B4DTN4|B4DTN4_HUMAN" 4 2068.0415 0.1 91868 26215 3 2068.03496 690.3545 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 3.92 3935 - 672979 - - - -3.1837 - 3.127 0.49 - 344.8 1 1 0 -0.0066 19 0 0 0 6.33E+05 6.14E+06 - - - 6.8021 1 221125_WJC_METTL3_EV_vs_WT_F06.26246.26246.4 1.87E-10 18/102 R.SPSELFAQHIVTIVHHVK.E "sp|Q9Y2W1|TR150_HUMAN,tr|A0A3B3ITZ9|A0A3B3ITZ9_HUMAN" 2 2041.1109 2.74 91885 26246 4 2041.112929 511.285 Thyroid hormone receptor-associated protein 3 OS=Homo sapiens OX=9606 GN=THRAP3 PE=1 SV=2 6.78 3939 - 531330 - - - 0.9965 - 3.33 0.644 - 269 1 2 0 0.002 18 0 0 0 6.37E+06 2.33E+06 - - - 5.2429 1 221125_WJC_METTL3_EV_vs_WT_F06.26248.26248.3 1.30E-10 19/68 K.GHYTEGAELVDSVLDVVR[166.11].K "sp|Q9BVA1|TBB2B_HUMAN,sp|P07437|TBB5_HUMAN,sp|Q13509|TBB3_HUMAN,sp|Q13885|TBB2A_HUMAN,sp|P68371|TBB4B_HUMAN,tr|A0A0B4J269|A0A0B4J269_HUMAN,tr|Q5ST81|Q5ST81_HUMAN,tr|Q5JP53|Q5JP53_HUMAN,tr|G3V2A3|G3V2A3_HUMAN" 9 1967.9828 1.03 91886 26248 3 1967.98529 657.0015 Tubulin beta-2B chain OS=Homo sapiens OX=9606 GN=TUBB2B PE=1 SV=1 4.31 3939.2 - 506519 - - - 1.2698 - 3.125 0.678 - 522.4 1 2 0 0.0025 18 0 0 0 1.13E+07 1.09E+07 - - - 8.9356 1 221125_WJC_METTL3_EV_vs_WT_F06.26250.26250.4 1.79E-08 20/114 K.NVVHQLSVTLEDLYNGATR[166.11]K[136.11].L sp|P31689|DNJA1_HUMAN 1 2274.2087 0.43 91887 26250 4 2274.211175 569.5595 DnaJ homolog subfamily A member 1 OS=Homo sapiens OX=9606 GN=DNAJA1 PE=1 SV=2 6.75 3939.5 - 386356 - - - 1.0817 - 3.222 0.497 - 254.9 1 2 0 0.0025 20 0 0 0 1.49E+07 3.47E+07 - - - 3.9424 1 221125_WJC_METTL3_EV_vs_WT_F06.26254.26254.3 1.35E-10 16/68 K.GHYTEGAELVDSVLDVVR.K "sp|Q9BVA1|TBB2B_HUMAN,sp|P07437|TBB5_HUMAN,sp|Q13509|TBB3_HUMAN,sp|Q13885|TBB2A_HUMAN,sp|P68371|TBB4B_HUMAN,tr|A0A0B4J269|A0A0B4J269_HUMAN,tr|Q5ST81|Q5ST81_HUMAN,tr|Q5JP53|Q5JP53_HUMAN,tr|G3V2A3|G3V2A3_HUMAN" 9 1957.9745 1.06 91889 26254 3 1957.975598 653.6655 Tubulin beta-2B chain OS=Homo sapiens OX=9606 GN=TUBB2B PE=1 SV=1 4.31 3940 - 369557 - - - 0.5501 - 3.14 0.67 - 371.9 1 2 0 0.0011 18 0 0 0 1.16E+07 1.09E+07 - - - 8.8588 1 221125_WJC_METTL3_EV_vs_WT_F06.26259.26259.3 8.34E-08 33/76 K.NVVHQLSVTLEDLYNGATR[166.11]K[136.11].L sp|P31689|DNJA1_HUMAN 1 2274.2087 0.37 91892 26259 3 2274.211492 759.0768 DnaJ homolog subfamily A member 1 OS=Homo sapiens OX=9606 GN=DNAJA1 PE=1 SV=2 6.75 3940.7 - 796159 - - - 1.2211 - 5.638 0.621 - 1660.1 1 2 0 0.0028 20 0 0 0 1.27E+07 3.38E+07 - - - 9.6586 1 221125_WJC_METTL3_EV_vs_WT_F06.26260.26260.4 9.03E-11 37/144 R.R[166.11]K[136.11]LEGDSTDLSDQIAELQAQIAELK[136.11].M sp|P35579|MYH9_HUMAN 1 2796.4715 0.76 91893 26260 4 2796.473302 700.1252 Myosin-9 OS=Homo sapiens OX=9606 GN=MYH9 PE=1 SV=4 4.3 3940.8 - 1.57E+06 - - - 0.6308 - 5.379 0.649 - 932.5 1 2 1 0.0018 25 0 0 0 4.42E+07 5.83E+07 - - - 5.4096 1 221125_WJC_METTL3_EV_vs_WT_F06.26264.26264.4 1.96E-08 27/144 R.RKLEGDSTDLSDQIAELQAQIAELK.M sp|P35579|MYH9_HUMAN 1 2770.4349 0.76 91895 26264 4 2770.437167 693.616 Myosin-9 OS=Homo sapiens OX=9606 GN=MYH9 PE=1 SV=4 4.3 3941.3 - 2.44E+06 - - - 0.8298 - 4.135 0.623 - 464.4 1 2 1 0.0023 25 0 0 0 4.42E+07 5.83E+07 - - - 5.0995 1 221125_WJC_METTL3_EV_vs_WT_F06.26268.26268.3 1.58E-14 27/96 R.RKLEGDSTDLSDQIAELQAQIAELK.M sp|P35579|MYH9_HUMAN 1 2770.4349 1.83 91897 26268 3 2770.433887 924.4856 Myosin-9 OS=Homo sapiens OX=9606 GN=MYH9 PE=1 SV=4 4.3 3941.9 - 871691 - - - -0.3541 - 5.23 0.716 - 1001.5 1 2 1 -0.001 25 0 0 0 2.93E+07 1.60E+07 - - - 10.3286 0.9999 221125_WJC_METTL3_EV_vs_WT_F06.26271.26271.4 3.18E-07 17/114 K.NVVHQLSVTLEDLYNGATRK.L sp|P31689|DNJA1_HUMAN 1 2256.1862 0.43 91900 26271 4 2256.189963 565.0538 DnaJ homolog subfamily A member 1 OS=Homo sapiens OX=9606 GN=DNAJA1 PE=1 SV=2 6.75 3942.2 - 1.10E+06 - - - 1.6479 - 3.185 0.409 - 185.2 1 2 0 0.0037 20 0 0 0 1.49E+07 3.47E+07 - - - 3.1722 1 221125_WJC_METTL3_EV_vs_WT_F06.26275.26275.4 4.39E-16 50/228 R.LTSWYLNQAGGDLGHLASAAAAAAAAGYPGQQQNFHSVR.E sp|Q12948|FOXC1_HUMAN 1 3968.9306 2.07 91902 26275 4 3968.936 993.2399 Forkhead box protein C1 OS=Homo sapiens OX=9606 GN=FOXC1 PE=1 SV=3 6.92 3942.7 - 2.81E+06 - - - 1.349 - 6.717 0.599 - 811.3 1 2 0 0.0054 39 0 0 0 5.84E+07 2.82E+07 - - - 4.9908 1 221125_WJC_METTL3_EV_vs_WT_F06.26276.26276.3 2.88E-11 28/96 R.R[166.11]K[136.11]LEGDSTDLSDQIAELQAQIAELK[136.11].M sp|P35579|MYH9_HUMAN 1 2796.4715 1.83 91903 26276 3 2796.465842 933.1645 Myosin-9 OS=Homo sapiens OX=9606 GN=MYH9 PE=1 SV=4 4.3 3942.9 - 645714 - - - -2.0369 - 5.502 0.654 - 1008.7 1 2 1 -0.0057 25 0 0 0 2.93E+07 1.60E+07 - - - 9.7527 1 221125_WJC_METTL3_EV_vs_WT_F06.26279.26279.3 1.70E-12 33/76 K.NVVHQLSVTLEDLYNGATRK.L sp|P31689|DNJA1_HUMAN 1 2256.1862 0.37 91904 26279 3 2256.187895 753.0694 DnaJ homolog subfamily A member 1 OS=Homo sapiens OX=9606 GN=DNAJA1 PE=1 SV=2 6.75 3943.3 - 839714 - - - 0.7313 - 4.682 0.688 - 680.9 1 2 0 0.0016 20 0 0 0 1.27E+07 3.38E+07 - - - 9.9552 0.9992 221125_WJC_METTL3_EV_vs_WT_F06.26287.26287.4 8.93E-05 15/156 R.RATVVVGDLHPLRDALPELLGLEAGSR.R "sp|Q9NSI2|SLX9_HUMAN,tr|C9JJU7|C9JJU7_HUMAN" 2 2853.5825 1.88 91908 26287 4 2853.589719 714.4029 Ribosome biogenesis protein SLX9 homolog OS=Homo sapiens OX=9606 GN=SLX9 PE=1 SV=2 5.48 3944.2 - 345679 - - - 2.5386 - 2.531 0.429 - 111 1 2 1 0.0072 27 0 0 0 4.28E+06 2.28E+06 - - - 3.2486 1 221125_WJC_METTL3_EV_vs_WT_F06.26288.26288.4 5.46E-05 12/108 R.GLLQDDAHPTLVTYADHSK[136.11].L "sp|Q86U44|MTA70_HUMAN,tr|F5H6D8|F5H6D8_HUMAN,tr|H0YFV6|H0YFV6_HUMAN,tr|B4DTN4|B4DTN4_HUMAN" 4 2088.0367 0.01 91909 26288 4 2088.034674 523.0165 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 5.13 3944.3 - 758524 - - - -0.9861 - 2.643 0.487 - 64.7 1 2 0 -0.0021 19 0 0 0 1.25E+05 2.18E+07 - - - 3.7931 0.9994 221125_WJC_METTL3_EV_vs_WT_F06.26291.26291.4 4.85E-08 42/228 R.LTSWYLNQAGGDLGHLASAAAAAAAAGYPGQQQNFHSVR[166.11].E sp|Q12948|FOXC1_HUMAN 1 3978.9389 2.07 91910 26291 4 3979.939379 995.742 Forkhead box protein C1 OS=Homo sapiens OX=9606 GN=FOXC1 PE=1 SV=3 6.92 3944.7 - 1.96E+06 - - - 251.4396 - 6.22 0.539 - 508.5 1 2 0 1.0005 39 0 0 0 5.84E+07 2.82E+07 - - - 4.1706 0.9999 221125_WJC_METTL3_EV_vs_WT_F06.26294.26294.3 0.000135 Nov-72 R.GLLQDDAHPTLVTYADHSK[136.11].L "sp|Q86U44|MTA70_HUMAN,tr|F5H6D8|F5H6D8_HUMAN,tr|H0YFV6|H0YFV6_HUMAN,tr|B4DTN4|B4DTN4_HUMAN" 4 2088.0367 0.15 91913 26294 3 2088.035455 697.0195 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 5.13 3945.1 - 311222 - - - -0.6121 - 2.108 0.451 - 100.1 1 2 0 -0.0013 19 0 0 0 2.31E+06 1.58E+07 - - - 5.4 0.9999 221125_WJC_METTL3_EV_vs_WT_F06.26301.26301.4 5.28E-07 23/150 R.SFGTEDRPTDRPIPPRDEVFEYIIFR.G "sp|Q8ND56|LS14A_HUMAN,tr|I3L4Q1|I3L4Q1_HUMAN,tr|A0A140TA76|A0A140TA76_HUMAN,tr|K7EMZ9|K7EMZ9_HUMAN" 4 3151.5727 1 91918 26301 4 3151.579481 788.9005 Protein LSM14 homolog A OS=Homo sapiens OX=9606 GN=LSM14A PE=1 SV=3 4.59 3946.1 - 2.62E+06 - - - 2.1519 - 2.945 0.551 - 80.6 1 2 1 0.0068 26 0 0 0 2.54E+07 2.53E+07 - - - 4.3607 1 221125_WJC_METTL3_EV_vs_WT_F06.26311.26311.3 7.57E-11 17/116 K.DMAIATGGAVFGEEGLTLNLEDVQPHDLGK[136.11].V "sp|P10809|CH60_HUMAN,tr|A0A7I2V2X6|A0A7I2V2X6_HUMAN,tr|A0A7I2YQK6|A0A7I2YQK6_HUMAN,tr|A0A7I2V599|A0A7I2V599_HUMAN" 4 3104.5216 2 91924 26311 3 3104.52922 1035.8478 "60 kDa heat shock protein, mitochondrial OS=Homo sapiens OX=9606 GN=HSPD1 PE=1 SV=2" 4.01 3947.4 - 459424 - - - 2.4606 - 3.521 0.651 - 179.2 1 2 0 0.0076 30 0 0 0 1.55E+07 7.75E+06 - - - 8.6918 1 221125_WJC_METTL3_EV_vs_WT_F06.26314.26314.4 1.68E-11 30/144 K.R[166.11]K[136.11]LDGETTDLQDQIAELQAQIDELK[136.11].L sp|P35580|MYH10_HUMAN 1 2895.5036 0.94 91925 26314 4 2895.510387 724.8832 Myosin-10 OS=Homo sapiens OX=9606 GN=MYH10 PE=1 SV=3 4.14 3947.8 - 914686 - - - 2.3557 - 4.981 0.636 - 722.8 1 2 1 0.0068 25 0 0 0 2.02E+07 2.14E+07 - - - 5.2706 0.9998 221125_WJC_METTL3_EV_vs_WT_F06.26315.26315.4 2.28E-09 29/144 K.RKLDGETTDLQDQIAELQAQIDELK.L sp|P35580|MYH10_HUMAN 1 2869.4669 0.94 91926 26315 4 2869.474198 718.374 Myosin-10 OS=Homo sapiens OX=9606 GN=MYH10 PE=1 SV=3 4.14 3947.9 - 890747 - - - 2.5447 - 4.529 0.55 - 707.6 1 2 1 0.0073 25 0 0 0 2.02E+07 2.14E+07 - - - 4.4917 1 221125_WJC_METTL3_EV_vs_WT_F06.26327.26327.4 3.24E-14 38/198 R.LGQHVPTLHPTSEELTIAGMTFTTFDLGGHEQAR.R "sp|Q9NR31|SAR1A_HUMAN,tr|Q5SQT8|Q5SQT8_HUMAN" 2 3690.81 2.47 91932 26327 4 3690.798996 923.7098 GTP-binding protein SAR1a OS=Homo sapiens OX=9606 GN=SAR1A PE=1 SV=1 5.26 3949.4 - 1.46E+06 - - - -2.9937 - 6.329 0.656 - 848.3 1 2 0 -0.0111 34 0 0 0 7.45E+06 3.02E+06 - - - 5.483 1 221125_WJC_METTL3_EV_vs_WT_F06.26328.26328.3 4.56E-10 22/96 K.R[166.11]K[136.11]LDGETTDLQDQIAELQAQIDELK[136.11].L sp|P35580|MYH10_HUMAN 1 2895.5036 0.74 91933 26328 3 2895.506239 966.1751 Myosin-10 OS=Homo sapiens OX=9606 GN=MYH10 PE=1 SV=3 4.14 3949.6 - 1.15E+06 - - - 0.9232 - 4.76 0.613 - 536 1 2 1 0.0027 25 0 0 0 3.92E+06 5.32E+06 - - - 8.9632 1 221125_WJC_METTL3_EV_vs_WT_F06.26330.26330.3 5.35E-05 Dec-60 K.K[136.11]VSQEILELLNTTTAK[136.11].E "sp|Q86U44|MTA70_HUMAN,tr|H0YFV6|H0YFV6_HUMAN" 2 1803.0324 0.001 91935 26330 3 1803.033306 602.0181 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 6.14 3949.9 - 209357 - - - 0.4858 - 2.94 0.525 - 258.1 1 2 0 0.0009 16 0 0 0 0.00E+00 3.11E+06 - - - 7.16 0.9999 221125_WJC_METTL3_EV_vs_WT_F06.26334.26334.4 3.47E-09 20/198 R.LGQHVPTLHPTSEELTIAGMTFTTFDLGGHEQAR[166.11].R "sp|Q9NR31|SAR1A_HUMAN,tr|Q5SQT8|Q5SQT8_HUMAN" 2 3700.8183 2.43 91937 26334 4 3700.825253 926.2119 GTP-binding protein SAR1a OS=Homo sapiens OX=9606 GN=SAR1A PE=1 SV=1 5.26 3950.4 - 414972 - - - 1.8747 - 4.017 0.443 - 160 1 2 0 0.0069 34 0 0 0 7.33E+06 3.02E+06 - - - 3.4946 1 221125_WJC_METTL3_EV_vs_WT_F06.26343.26343.3 2.09E-13 17/116 K.DMAIATGGAVFGEEGLTLNLEDVQPHDLGK.V "sp|P10809|CH60_HUMAN,tr|A0A7I2V2X6|A0A7I2V2X6_HUMAN,tr|A0A7I2YQK6|A0A7I2YQK6_HUMAN,tr|A0A7I2V599|A0A7I2V599_HUMAN" 4 3096.5074 2.06 91943 26343 3 3096.512844 1033.1764 "60 kDa heat shock protein, mitochondrial OS=Homo sapiens OX=9606 GN=HSPD1 PE=1 SV=2" 4.01 3951.5 - 590146 - - - 1.7642 - 3.644 0.708 - 172.7 1 2 0 0.0055 30 0 0 0 1.59E+07 7.75E+06 - - - 9.4069 0.9999 221125_WJC_METTL3_EV_vs_WT_F06.26370.26370.4 1.43E-08 16/102 K.STSESFIQHIVSLVHHVK.E "sp|Q9NYF8|BCLF1_HUMAN,tr|E9PKI6|E9PKI6_HUMAN,tr|A0A1W2PQ43|A0A1W2PQ43_HUMAN,tr|E9PK91|E9PK91_HUMAN,tr|E9PJA7|E9PJA7_HUMAN,tr|E9PK09|E9PK09_HUMAN,tr|E9PQN2|E9PQN2_HUMAN" 7 2047.0851 1.78 91951 26370 4 2047.086758 512.7785 Bcl-2-associated transcription factor 1 OS=Homo sapiens OX=9606 GN=BCLAF1 PE=1 SV=2 6.78 3955.5 - 721043 - - - 0.8226 - 2.893 0.405 - 152.3 1 2 0 0.0017 18 0 0 0 5.43E+06 3.05E+06 - - - 3.1145 1 221125_WJC_METTL3_EV_vs_WT_F06.26373.26373.4 2.23E-12 34/240 K.VSELNPNAEVWGAPVLHLEASSAADGVSAAWEEVAGHHADR.G "sp|Q92615|LAR4B_HUMAN,tr|B5MCU2|B5MCU2_HUMAN" 2 4248.0261 1.56 91953 26373 4 4248.031305 1063.0138 La-related protein 4B OS=Homo sapiens OX=9606 GN=LARP4B PE=1 SV=3 4.47 3955.8 - 1.17E+06 - - - 1.234 - 5.635 0.642 - 589.1 1 2 0 0.0052 41 0 0 0 1.01E+07 6.45E+06 - - - 5.3092 0.9965 221125_WJC_METTL3_EV_vs_WT_F06.26382.26382.4 3.85E-07 26/198 K.TIGTK[136.11]PVAHIDQFTADMLGSAELAEEVNLNGSGK[136.11].L sp|P50991|TCPD_HUMAN 1 3528.7741 0.21 91956 26382 4 3529.769792 883.2008 T-complex protein 1 subunit delta OS=Homo sapiens OX=9606 GN=CCT4 PE=1 SV=4 4.5 3957 - 1.02E+06 - - - 282.1597 - 3.578 0.475 - 245.7 1 2 0 0.9957 34 0 0 0 1.84E+06 8.74E+06 - - - 3.4648 1 221125_WJC_METTL3_EV_vs_WT_F06.26384.26384.4 4.62E-10 43/162 R.HVDAHATLSDGVVVQVMGLLSNSGQPER.K "sp|Q9UN86|G3BP2_HUMAN,tr|A0A7I2V3E2|A0A7I2V3E2_HUMAN,tr|D6RAC7|D6RAC7_HUMAN,tr|D6RB17|D6RB17_HUMAN,tr|A0A7I2YQS2|A0A7I2YQS2_HUMAN,tr|A0A7I2YQG8|A0A7I2YQG8_HUMAN,tr|A0A7I2V572|A0A7I2V572_HUMAN,tr|D6RBW8|D6RBW8_HUMAN" 8 2915.456 0.62 91958 26384 4 2915.460782 729.8713 Ras GTPase-activating protein-binding protein 2 OS=Homo sapiens OX=9606 GN=G3BP2 PE=1 SV=2 5.21 3957.2 - 1.08E+06 - - - 1.656 - 4.986 0.608 - 1357.8 1 2 0 0.0048 28 0 0 0 1.20E+07 1.93E+07 - - - 5.0155 1 221125_WJC_METTL3_EV_vs_WT_F06.26387.26387.3 6.50E-12 20/60 R.THNLEPYFESFINNLR.R sp|P04264|K2C1_HUMAN 1 1992.9694 381.44 91959 26387 3 1992.973826 665.3304 "Keratin, type II cytoskeletal 1 OS=Homo sapiens OX=9606 GN=KRT1 PE=1 SV=6" 5.37 3957.6 - 6.89E+06 - - - 2.2328 - 3.783 0.686 - 798.3 1 2 0 0.0044 16 0 0 0 1.58E+08 4.14E+05 - - - 9.6009 0.9188 221125_WJC_METTL3_EV_vs_WT_F06.26389.26389.4 4.49E-05 23/162 R.K[136.11]DGNASGTTLLEALDC[160.03]ILPPTR[166.11]PTDK[136.11]PL.R "sp|P68104|EF1A1_HUMAN,sp|Q5VTE0|EF1A3_HUMAN,tr|A0A7I2V659|A0A7I2V659_HUMAN,tr|A0A7I2V3H3|A0A7I2V3H3_HUMAN,tr|A0A7I2V5N4|A0A7I2V5N4_HUMAN,tr|A0A087WVQ9|A0A087WVQ9_HUMAN,tr|A0A087WV01|A0A087WV01_HUMAN" 7 3018.5906 0.63 91961 26389 4 3018.606847 755.6549 Elongation factor 1-alpha 1 OS=Homo sapiens OX=9606 GN=EEF1A1 PE=1 SV=1 4.68 3957.9 - 772369 - - - 5.38 - 3.25 0.481 - 197.4 1 1 0 0.0162 28 0 0 0 5.47E+06 8.70E+06 - - - 3.7741 1 221125_WJC_METTL3_EV_vs_WT_F06.26395.26395.4 1.76E-06 13/90 R.THNLEPYFESFINNLR.R sp|P04264|K2C1_HUMAN 1 1992.9694 999 91965 26395 4 1992.97173 499.2496 "Keratin, type II cytoskeletal 1 OS=Homo sapiens OX=9606 GN=KRT1 PE=1 SV=6" 5.37 3958.6 - 274639 - - - 1.1812 - 2.063 0.561 - 80.6 1 2 0 0.0024 16 0 0 0 4.59E+06 0.00E+00 - - - 4.3634 1 221125_WJC_METTL3_EV_vs_WT_F06.26399.26399.4 3.72E-15 31/162 R.HVDAHATLSDGVVVQVMGLLSNSGQPER[166.11].K "sp|Q9UN86|G3BP2_HUMAN,tr|A0A7I2V3E2|A0A7I2V3E2_HUMAN,tr|D6RAC7|D6RAC7_HUMAN,tr|D6RB17|D6RB17_HUMAN,tr|A0A7I2YQS2|A0A7I2YQS2_HUMAN,tr|A0A7I2YQG8|A0A7I2YQG8_HUMAN,tr|A0A7I2V572|A0A7I2V572_HUMAN,tr|D6RBW8|D6RBW8_HUMAN" 8 2925.4642 1.02 91967 26399 4 2925.46498 732.3733 Ras GTPase-activating protein-binding protein 2 OS=Homo sapiens OX=9606 GN=G3BP2 PE=1 SV=2 5.21 3959.1 - 527551 - - - 0.2584 - 4.814 0.69 - 594 1 2 0 0.0008 28 0 0 0 1.26E+07 1.24E+07 - - - 5.7195 1 221125_WJC_METTL3_EV_vs_WT_F06.26421.26421.4 4.76E-11 42/162 R.HVDAHATLNDGVVVQVMGLLSNNNQALR.R "sp|Q13283|G3BP1_HUMAN,tr|A0A7I2YQB1|A0A7I2YQB1_HUMAN,tr|A0A7I2V5M7|A0A7I2V5M7_HUMAN,tr|E5RH42|E5RH42_HUMAN,tr|A0A7P0P2U7|A0A7P0P2U7_HUMAN,tr|A0A7I2YQU8|A0A7I2YQU8_HUMAN,tr|E5RJU8|E5RJU8_HUMAN,tr|A0A7I2V651|A0A7I2V651_HUMAN,tr|E5RIF8|E5RIF8_HUMAN,tr|A0A7I2YQN9|A0A7I2YQN9_HUMAN" 10 2984.525 1.16 91979 26421 4 2984.522364 747.1385 Ras GTPase-activating protein-binding protein 1 OS=Homo sapiens OX=9606 GN=G3BP1 PE=1 SV=1 5.98 3962 - 1.32E+07 - - - -0.8956 - 6.017 0.635 - 1141.8 1 2 0 -0.0027 28 0 0 0 2.10E+08 1.81E+08 - - - 5.3095 1 221125_WJC_METTL3_EV_vs_WT_F06.26423.26423.3 6.07E-11 26/84 R.K[136.11]PLVIIAEDVDGEALSTLVLNR[166.11].L "sp|P10809|CH60_HUMAN,tr|A0A7I2V2X6|A0A7I2V2X6_HUMAN,tr|A0A7I2YQK6|A0A7I2YQK6_HUMAN,tr|A0A7I2V599|A0A7I2V599_HUMAN,tr|A0A7I2YQ71|A0A7I2YQ71_HUMAN,tr|A0A7I2V5M1|A0A7I2V5M1_HUMAN,tr|A0A7I2V5K3|A0A7I2V5K3_HUMAN" 7 2382.3489 0.78 91981 26423 3 2382.346677 795.1236 "60 kDa heat shock protein, mitochondrial OS=Homo sapiens OX=9606 GN=HSPD1 PE=1 SV=2" 4.32 3962.2 - 3.48E+06 - - - -0.9319 - 5.025 0.637 - 893 1 2 0 -0.0022 22 0 0 0 4.58E+07 5.88E+07 - - - 9.4688 0.9999 221125_WJC_METTL3_EV_vs_WT_F06.26426.26426.4 1.80E-10 43/162 R.HVDAHATLNDGVVVQVMGLLSNNNQALR[166.11].R "sp|Q13283|G3BP1_HUMAN,tr|A0A7I2YQB1|A0A7I2YQB1_HUMAN,tr|A0A7I2V5M7|A0A7I2V5M7_HUMAN,tr|E5RH42|E5RH42_HUMAN,tr|A0A7P0P2U7|A0A7P0P2U7_HUMAN,tr|A0A7I2YQU8|A0A7I2YQU8_HUMAN,tr|E5RJU8|E5RJU8_HUMAN,tr|A0A7I2V651|A0A7I2V651_HUMAN,tr|E5RIF8|E5RIF8_HUMAN,tr|A0A7I2YQN9|A0A7I2YQN9_HUMAN" 10 2994.5333 1.16 91982 26426 4 2994.529537 749.6406 Ras GTPase-activating protein-binding protein 1 OS=Homo sapiens OX=9606 GN=G3BP1 PE=1 SV=1 5.98 3962.6 - 2.55E+07 - - - -1.259 - 5.622 0.383 - 1304.7 1 2 0 -0.0038 28 0 0 0 2.08E+08 1.80E+08 - - - 3.0947 1 221125_WJC_METTL3_EV_vs_WT_F06.26428.26428.3 1.99E-13 39/108 R.HVDAHATLNDGVVVQVMGLLSNNNQALR.R "sp|Q13283|G3BP1_HUMAN,tr|A0A7I2YQB1|A0A7I2YQB1_HUMAN,tr|A0A7I2V5M7|A0A7I2V5M7_HUMAN,tr|E5RH42|E5RH42_HUMAN,tr|A0A7P0P2U7|A0A7P0P2U7_HUMAN,tr|A0A7I2YQU8|A0A7I2YQU8_HUMAN,tr|E5RJU8|E5RJU8_HUMAN,tr|A0A7I2V651|A0A7I2V651_HUMAN,tr|E5RIF8|E5RIF8_HUMAN,tr|A0A7I2YQN9|A0A7I2YQN9_HUMAN" 10 2984.525 1.24 91984 26428 3 2984.519365 995.849 Ras GTPase-activating protein-binding protein 1 OS=Homo sapiens OX=9606 GN=G3BP1 PE=1 SV=1 5.98 3962.8 - 4.12E+06 - - - -1.9005 - 6.535 0.711 - 1775.2 1 2 0 -0.0057 28 0 0 0 2.93E+07 2.36E+07 - - - 10.7841 1 221125_WJC_METTL3_EV_vs_WT_F06.26436.26436.3 4.07E-12 38/108 R.HVDAHATLNDGVVVQVMGLLSNNNQALR[166.11].R "sp|Q13283|G3BP1_HUMAN,tr|A0A7I2YQB1|A0A7I2YQB1_HUMAN,tr|A0A7I2V5M7|A0A7I2V5M7_HUMAN,tr|E5RH42|E5RH42_HUMAN,tr|A0A7P0P2U7|A0A7P0P2U7_HUMAN,tr|A0A7I2YQU8|A0A7I2YQU8_HUMAN,tr|E5RJU8|E5RJU8_HUMAN,tr|A0A7I2V651|A0A7I2V651_HUMAN,tr|E5RIF8|E5RIF8_HUMAN,tr|A0A7I2YQN9|A0A7I2YQN9_HUMAN" 10 2994.5333 1.24 91988 26436 3 2994.528411 999.185 Ras GTPase-activating protein-binding protein 1 OS=Homo sapiens OX=9606 GN=G3BP1 PE=1 SV=1 5.98 3963.9 - 2.38E+06 - - - -1.635 - 6.221 0.491 - 1902.5 1 2 0 -0.0049 28 0 0 0 2.93E+07 2.36E+07 - - - 8.2182 1 221125_WJC_METTL3_EV_vs_WT_F06.26443.26443.3 1.30E-07 16/76 K.HAASDVDLEIESLLNQQSTK[136.11].E "sp|Q86U44|MTA70_HUMAN,tr|F5H6D8|F5H6D8_HUMAN,tr|H0YFV6|H0YFV6_HUMAN,tr|B4DTN4|B4DTN4_HUMAN" 4 2205.1005 0.49 91993 26443 3 2205.096893 736.0408 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 4.31 3964.8 - 742969 - - - -1.6158 - 3.444 0.586 - 312.5 1 2 0 -0.0036 20 0 0 0 2.60E+07 5.30E+07 - - - 8.0724 0.983 221125_WJC_METTL3_EV_vs_WT_F06.26444.26444.3 1.65E-07 18/80 K.R[166.11]R[166.11]AEQDSTTVAAFASSLVSGL.N "sp|Q86U44|MTA70_HUMAN,tr|F5H6D8|F5H6D8_HUMAN,tr|H0YFV6|H0YFV6_HUMAN,tr|B4DTN4|B4DTN4_HUMAN" 4 2185.1242 0 91994 26444 3 2185.121685 729.382 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 6.07 3964.8 - 3.48E+06 - - - -1.151 - 3.009 0.466 - 372.4 1 1 1 -0.0025 21 0 0 0 3.78E+05 1.34E+08 - - - 6.3758 1 221125_WJC_METTL3_EV_vs_WT_F06.26449.26449.3 6.58E-11 17/68 K.YVHYEIDAC[160.03]MDSEAPGSK[136.11].D "sp|Q86U44|MTA70_HUMAN,tr|H0YFV6|H0YFV6_HUMAN" 2 2078.8805 0 91996 26449 3 2078.883466 693.9674 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 4.31 3965.6 - 1.01E+06 - - - 1.4306 - 3.378 0.674 - 325.1 1 2 0 0.003 18 0 0 0 1.75E+05 3.92E+07 - - - 9.0848 1 221125_WJC_METTL3_EV_vs_WT_F06.26451.26451.4 1.59E-15 38/198 K.QSK[136.11]PVTTPEEIAQVATISANGDK[136.11]EIGNIISDAMK[136.11].K "sp|P10809|CH60_HUMAN,tr|A0A7I2V599|A0A7I2V599_HUMAN,tr|E7EXB4|E7EXB4_HUMAN,tr|A0A7I2YQ71|A0A7I2YQ71_HUMAN,tr|E7ESH4|E7ESH4_HUMAN,tr|A0A7I2V5M1|A0A7I2V5M1_HUMAN,tr|A0A7I2V5K3|A0A7I2V5K3_HUMAN,tr|A0A7I2V369|A0A7I2V369_HUMAN" 8 3578.8564 1.41 91998 26451 4 3578.85131 895.7214 "60 kDa heat shock protein, mitochondrial OS=Homo sapiens OX=9606 GN=HSPD1 PE=1 SV=2" 4.51 3965.8 - 7.82E+06 - - - -1.4203 - 6.39 0.63 - 853.7 1 2 1 -0.0051 34 0 0 0 7.14E+09 5.07E+09 - - - 5.2612 0.9999 221125_WJC_METTL3_EV_vs_WT_F06.26452.26452.2 0.00483 15/22 R.NLDLDSIIAEVK.A "sp|P48668|K2C6C_HUMAN,sp|P04259|K2C6B_HUMAN,sp|P13647|K2C5_HUMAN,sp|P35908|K22E_HUMAN,sp|O95678|K2C75_HUMAN,sp|Q5XKE5|K2C79_HUMAN,sp|P02538|K2C6A_HUMAN,tr|H0YI76|H0YI76_HUMAN,tr|H0YIN9|H0YIN9_HUMAN" 9 1328.7187 13.34 91999 26452 2 1328.717124 665.3666 "Keratin, type II cytoskeletal 6C OS=Homo sapiens OX=9606 GN=KRT6C PE=1 SV=3" 4.03 3965.8 - 2.44E+06 - - - -1.2215 - 2.659 0.501 - 612.4 1 2 0 -0.0016 12 0 0 0 3.29E+07 2.46E+06 - - - 5.314 1 221125_WJC_METTL3_EV_vs_WT_F06.26456.26456.2 0.00129 15/22 R.SLDLDSIIAEVK.A sp|P04264|K2C1_HUMAN 1 1301.7078 999 92000 26456 2 1301.707842 651.8612 "Keratin, type II cytoskeletal 1 OS=Homo sapiens OX=9606 GN=KRT1 PE=1 SV=6" 4.03 3966.4 - 2.33E+06 - - - -0.0046 - 2.86 0.538 - 607.9 1 2 0 0 12 0 0 0 4.36E+07 0.00E+00 - - - 5.7796 1 221125_WJC_METTL3_EV_vs_WT_F06.26458.26458.4 6.34E-11 36/162 K.QLQELEDKQNADISAMQDTINKLENELR.T sp|P07196|NFL_HUMAN 1 3285.6147 1.84 92001 26458 4 3285.617305 822.411 Neurofilament light polypeptide OS=Homo sapiens OX=9606 GN=NEFL PE=1 SV=3 4.2 3966.6 - 2.87E+06 - - - 0.7932 - 5.692 0.667 - 1014.6 1 2 2 0.0026 28 0 0 0 7.79E+07 4.23E+07 - - - 5.5708 1 221125_WJC_METTL3_EV_vs_WT_F06.26460.26460.4 2.41E-12 33/162 K.QLQELEDK[136.11]QNADISAMQDTINK[136.11]LENELR[166.11].T sp|P07196|NFL_HUMAN 1 3311.6514 1.87 92002 26460 4 3311.646194 828.9201 Neurofilament light polypeptide OS=Homo sapiens OX=9606 GN=NEFL PE=1 SV=3 4.2 3966.8 - 2.48E+06 - - - -1.5627 - 5.297 0.632 - 869.1 1 2 2 -0.0052 28 0 0 0 7.68E+07 4.10E+07 - - - 5.2431 1 221125_WJC_METTL3_EV_vs_WT_F06.26463.26463.4 3.84E-08 27/252 K.QPVPVGGAISTAQAQAFLGHLHQVQLAGTSLQAAAQSLNVQSK.S "sp|P14859|PO2F1_HUMAN,tr|A0A0A0MT46|A0A0A0MT46_HUMAN" 2 4321.2931 2.28 92003 26463 4 4321.291164 1081.3306 "POU domain, class 2, transcription factor 1 OS=Homo sapiens OX=9606 GN=POU2F1 PE=1 SV=2" 8.76 3967.2 - 3.31E+06 - - - -0.4519 - 4.792 0.477 - 254.6 1 2 0 -0.002 43 0 0 0 5.75E+07 2.52E+07 - - - 3.8232 1 221125_WJC_METTL3_EV_vs_WT_F06.26468.26468.3 4.99E-12 31/132 K.QSKPVTTPEEIAQVATISANGDKEIGNIISDAMK.K "sp|P10809|CH60_HUMAN,tr|A0A7I2V599|A0A7I2V599_HUMAN,tr|E7EXB4|E7EXB4_HUMAN,tr|A0A7I2YQ71|A0A7I2YQ71_HUMAN,tr|E7ESH4|E7ESH4_HUMAN,tr|A0A7I2V5M1|A0A7I2V5M1_HUMAN,tr|A0A7I2V5K3|A0A7I2V5K3_HUMAN,tr|A0A7I2V369|A0A7I2V369_HUMAN" 8 3554.8138 1.52 92006 26468 3 3554.816156 1185.9452 "60 kDa heat shock protein, mitochondrial OS=Homo sapiens OX=9606 GN=HSPD1 PE=1 SV=2" 4.51 3967.8 - 2.27E+06 - - - 0.6647 - 5.542 0.666 - 507.4 1 2 1 0.0024 34 0 0 0 6.22E+08 4.10E+08 - - - 9.9041 1 221125_WJC_METTL3_EV_vs_WT_F06.26480.26480.3 1.13E-07 46/132 K.QSK[136.11]PVTTPEEIAQVATISANGDK[136.11]EIGNIISDAMK[136.11].K "sp|P10809|CH60_HUMAN,tr|A0A7I2V599|A0A7I2V599_HUMAN,tr|E7EXB4|E7EXB4_HUMAN,tr|A0A7I2YQ71|A0A7I2YQ71_HUMAN,tr|E7ESH4|E7ESH4_HUMAN,tr|A0A7I2V5M1|A0A7I2V5M1_HUMAN,tr|A0A7I2V5K3|A0A7I2V5K3_HUMAN,tr|A0A7I2V369|A0A7I2V369_HUMAN" 8 3578.8564 1.52 92012 26480 3 3578.848135 1193.9594 "60 kDa heat shock protein, mitochondrial OS=Homo sapiens OX=9606 GN=HSPD1 PE=1 SV=2" 4.51 3969.5 - 6.36E+06 - - - -2.3074 - 5.901 0.664 - 1425.3 1 2 1 -0.0083 34 0 0 0 6.22E+08 4.10E+08 - - - 10.0246 1 221125_WJC_METTL3_EV_vs_WT_F06.26489.26489.4 1.04E-10 28/174 K.IVK[136.11]PNGEK[136.11]PDEFESGISQALLELEMNSDLK[136.11].A "sp|P62081|RS7_HUMAN,tr|B5MCP9|B5MCP9_HUMAN,tr|A0A2R8Y623|A0A2R8Y623_HUMAN" 3 3353.7127 1.04 92013 26489 4 3353.711958 839.4354 40S ribosomal protein S7 OS=Homo sapiens OX=9606 GN=RPS7 PE=1 SV=1 4.25 3970.9 - 6.02E+06 - - - -0.218 - 4.687 0.598 - 492.4 1 2 0 -0.0007 30 0 0 0 5.24E+07 5.04E+07 - - - 4.9035 0.998 221125_WJC_METTL3_EV_vs_WT_F06.26496.26496.3 0.0169 21/80 N.WITLGNQLDGIHLLDPDVVAR[166.11].F sp|Q86U44|MTA70_HUMAN 1 2354.2622 0 92015 26496 3 2354.257607 785.7613 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 4.41 3971.9 - 1.55E+07 - - - -1.9509 - 3.586 0.581 - 308.8 1 1 0 -0.0046 21 0 0 0 1.98E+06 4.75E+08 - - - 8.0779 1 221125_WJC_METTL3_EV_vs_WT_F06.26497.26497.4 8.64E-10 30/174 K.IVKPNGEKPDEFESGISQALLELEMNSDLK.A "sp|P62081|RS7_HUMAN,tr|B5MCP9|B5MCP9_HUMAN,tr|A0A2R8Y623|A0A2R8Y623_HUMAN" 3 3329.6701 1.04 92016 26497 4 3329.667423 833.4248 40S ribosomal protein S7 OS=Homo sapiens OX=9606 GN=RPS7 PE=1 SV=1 4.25 3972 - 4.24E+06 - - - -0.8007 - 5.013 0.609 - 633.4 1 2 0 -0.0027 30 0 0 0 5.24E+07 5.04E+07 - - - 5.0193 1 221125_WJC_METTL3_EV_vs_WT_F06.26501.26501.4 4.19E-13 24/162 K.DGNASGTTLLEALDC[160.03]ILPPTR[166.11]PTDK[136.11]PLR[166.11].L "sp|P68104|EF1A1_HUMAN,sp|Q5VTE0|EF1A3_HUMAN,tr|A0A7I2V659|A0A7I2V659_HUMAN,tr|A0A7I2V3H3|A0A7I2V3H3_HUMAN,tr|A0A7I2V5N4|A0A7I2V5N4_HUMAN,tr|A0A087WVQ9|A0A087WVQ9_HUMAN,tr|A0A087WV01|A0A087WV01_HUMAN" 7 3048.5908 0.31 92018 26501 4 3048.588005 763.155 Elongation factor 1-alpha 1 OS=Homo sapiens OX=9606 GN=EEF1A1 PE=1 SV=1 4.68 3972.5 - 5.07E+06 - - - -0.925 - 3.936 0.683 - 252.9 1 2 0 -0.0028 28 0 0 0 5.48E+08 1.79E+09 - - - 5.5955 1 221125_WJC_METTL3_EV_vs_WT_F06.26504.26504.3 1.20E-14 26/128 K.TQEDEEEISTSPGVSEFVSDAFDAC[160.03]NLNQEDLR.K sp|Q96A49|SYAP1_HUMAN 1 3730.6064 1.22 92019 26504 3 3730.602082 1244.5428 Synapse-associated protein 1 OS=Homo sapiens OX=9606 GN=SYAP1 PE=1 SV=1 3.51 3972.9 - 5.43E+06 - - - -1.1679 - 4.348 0.759 - 563.1 1 2 0 -0.0044 33 0 0 0 3.49E+07 2.85E+07 - - - 10.3822 1 221125_WJC_METTL3_EV_vs_WT_F06.26507.26507.4 1.18E-12 29/162 K.DGNASGTTLLEALDC[160.03]ILPPTRPTDKPLR.L "sp|P68104|EF1A1_HUMAN,sp|Q5VTE0|EF1A3_HUMAN,tr|A0A7I2V659|A0A7I2V659_HUMAN,tr|A0A7I2V3H3|A0A7I2V3H3_HUMAN,tr|A0A7I2V5N4|A0A7I2V5N4_HUMAN,tr|A0A087WVQ9|A0A087WVQ9_HUMAN,tr|A0A087WV01|A0A087WV01_HUMAN" 7 3020.5601 0.31 92020 26507 4 3020.558286 756.1473 Elongation factor 1-alpha 1 OS=Homo sapiens OX=9606 GN=EEF1A1 PE=1 SV=1 4.68 3973.3 - 1.72E+07 - - - -0.5956 - 4.292 0.685 - 403.2 1 2 0 -0.0018 28 0 0 0 5.48E+08 1.79E+09 - - - 5.64 1 221125_WJC_METTL3_EV_vs_WT_F06.26509.26509.3 3.69E-07 26/108 K.DGNASGTTLLEALDC[160.03]ILPPTR[166.11]PTDK[136.11]PLR[166.11].L "sp|P68104|EF1A1_HUMAN,sp|Q5VTE0|EF1A3_HUMAN,tr|A0A7I2V659|A0A7I2V659_HUMAN,tr|A0A7I2V3H3|A0A7I2V3H3_HUMAN,tr|A0A7I2V5N4|A0A7I2V5N4_HUMAN,tr|A0A087WVQ9|A0A087WVQ9_HUMAN,tr|A0A087WV01|A0A087WV01_HUMAN" 7 3048.5908 0.33 92022 26509 3 3048.582225 1017.2042 Elongation factor 1-alpha 1 OS=Homo sapiens OX=9606 GN=EEF1A1 PE=1 SV=1 4.68 3973.5 - 6.94E+06 - - - -2.821 - 3.292 0.627 - 612.2 1 2 0 -0.0086 28 0 0 0 8.28E+07 2.52E+08 - - - 8.2692 1 221125_WJC_METTL3_EV_vs_WT_F06.26514.26514.3 9.23E-12 23/108 K.DGNASGTTLLEALDC[160.03]ILPPTRPTDKPLR.L "sp|P68104|EF1A1_HUMAN,sp|Q5VTE0|EF1A3_HUMAN,tr|A0A7I2V659|A0A7I2V659_HUMAN,tr|A0A7I2V3H3|A0A7I2V3H3_HUMAN,tr|A0A7I2V5N4|A0A7I2V5N4_HUMAN,tr|A0A087WVQ9|A0A087WVQ9_HUMAN,tr|A0A087WV01|A0A087WV01_HUMAN" 7 3020.5601 0.33 92024 26514 3 3020.550744 1007.8606 Elongation factor 1-alpha 1 OS=Homo sapiens OX=9606 GN=EEF1A1 PE=1 SV=1 4.68 3974.1 - 3.54E+06 - - - -3.0925 - 3.527 0.669 - 448.3 1 2 0 -0.0093 28 0 0 0 8.28E+07 2.51E+08 - - - 8.8959 1 221125_WJC_METTL3_EV_vs_WT_F06.26517.26517.3 3.86E-12 18/128 K.TQEDEEEISTSPGVSEFVSDAFDAC[160.03]NLNQEDLR[166.11].K sp|Q96A49|SYAP1_HUMAN 1 3740.6147 1.22 92025 26517 3 3741.610535 1247.8788 Synapse-associated protein 1 OS=Homo sapiens OX=9606 GN=SYAP1 PE=1 SV=1 3.51 3974.4 - 1.73E+06 - - - 266.2199 - 4.009 0.726 - 294.6 1 2 0 0.9958 33 0 0 0 3.49E+07 2.85E+07 - - - 9.5529 1 221125_WJC_METTL3_EV_vs_WT_F06.26566.26566.4 3.68E-07 15/108 R.GLLQDDAHPTLVTYADHSK[136.11].L "sp|Q86U44|MTA70_HUMAN,tr|F5H6D8|F5H6D8_HUMAN,tr|H0YFV6|H0YFV6_HUMAN,tr|B4DTN4|B4DTN4_HUMAN" 4 2088.0367 0 92032 26566 4 2088.036704 523.0165 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 5.13 3982.1 - 580013 - - - -0.0139 - 2.815 0.584 - 236.4 1 2 0 0 19 0 0 0 1.26E+05 3.86E+07 - - - 4.6592 1 221125_WJC_METTL3_EV_vs_WT_F06.26594.26594.4 2.26E-11 35/186 K.VIHDNFGIVEGLMTTVHAITATQKTVDGPSGK.L "sp|P04406|G3P_HUMAN,tr|E7EUT5|E7EUT5_HUMAN" 2 3335.7184 1.04 92046 26594 4 3335.704701 834.9369 Glyceraldehyde-3-phosphate dehydrogenase OS=Homo sapiens OX=9606 GN=GAPDH PE=1 SV=3 6 3985.6 - 1.88E+06 - - - -4.0999 - 6.285 0.659 - 839.6 1 2 1 -0.0137 32 0 0 0 2.19E+07 2.11E+07 - - - 5.5132 1 221125_WJC_METTL3_EV_vs_WT_F06.26595.26595.4 2.67E-11 26/150 R.DFEGAVDLLDK[136.11]LNHYLEDK[136.11]PSPPPVK[136.11].E sp|Q8IYI6|EXOC8_HUMAN 1 2959.5393 2.48 92047 26595 4 2959.524357 740.8921 Exocyst complex component 8 OS=Homo sapiens OX=9606 GN=EXOC8 PE=1 SV=2 4.52 3985.8 - 1.52E+06 - - - -5.0626 - 4.629 0.666 - 214.9 1 2 1 -0.015 26 0 0 0 3.55E+07 1.43E+07 - - - 5.5021 1 221125_WJC_METTL3_EV_vs_WT_F06.26618.26618.4 5.42E-13 32/210 K.TC[160.03]NC[160.03]ETEDYGEK[136.11]FDENDVITC[160.03]FANFESDEVELSYAK[136.11].N "sp|Q00839|HNRPU_HUMAN,tr|A0A1W2PQL0|A0A1W2PQL0_HUMAN,tr|A0A1W2PPL4|A0A1W2PPL4_HUMAN,tr|A0A1W2PQ74|A0A1W2PQ74_HUMAN,tr|Q5RI18|Q5RI18_HUMAN,tr|A0A1W2PP35|A0A1W2PP35_HUMAN,tr|A0A1W2PPS1|A0A1W2PPS1_HUMAN,tr|A0A1W2PRZ7|A0A1W2PRZ7_HUMAN,tr|A0A1W2PPH7|A0A1W2PPH7_HUMAN,tr|A0A1W2PP34|A0A1W2PP34_HUMAN,tr|A0A1X7SBS1|A0A1X7SBS1_HUMAN" 11 4343.7952 0.86 92049 26618 4 4344.787293 1086.9561 Heterogeneous nuclear ribonucleoprotein U OS=Homo sapiens OX=9606 GN=HNRNPU PE=1 SV=6 3.73 3989.5 - 9.60E+06 - - - 228.3973 - 4.46 0.776 - 498.4 1 2 1 0.9921 36 0 0 0 1.62E+08 1.87E+08 - - - 6.1462 1 221125_WJC_METTL3_EV_vs_WT_F06.26621.26621.4 4.73E-15 34/210 K.TC[160.03]NC[160.03]ETEDYGEKFDENDVITC[160.03]FANFESDEVELSYAK.N "sp|Q00839|HNRPU_HUMAN,tr|A0A1W2PQL0|A0A1W2PQL0_HUMAN,tr|A0A1W2PPL4|A0A1W2PPL4_HUMAN,tr|A0A1W2PQ74|A0A1W2PQ74_HUMAN,tr|Q5RI18|Q5RI18_HUMAN,tr|A0A1W2PP35|A0A1W2PP35_HUMAN,tr|A0A1W2PPS1|A0A1W2PPS1_HUMAN,tr|A0A1W2PRZ7|A0A1W2PRZ7_HUMAN,tr|A0A1W2PPH7|A0A1W2PPH7_HUMAN,tr|A0A1W2PP34|A0A1W2PP34_HUMAN,tr|A0A1X7SBS1|A0A1X7SBS1_HUMAN" 11 4327.7668 0.86 92050 26621 4 4327.76107 1082.949 Heterogeneous nuclear ribonucleoprotein U OS=Homo sapiens OX=9606 GN=HNRNPU PE=1 SV=6 3.73 3989.9 - 1.42E+07 - - - -1.3198 - 5.328 0.818 - 604.5 1 2 1 -0.0057 36 0 0 0 1.62E+08 1.87E+08 - - - 6.8374 1 221125_WJC_METTL3_EV_vs_WT_F06.26626.26626.3 7.21E-15 27/140 K.TC[160.03]NC[160.03]ETEDYGEKFDENDVITC[160.03]FANFESDEVELSYAK.N "sp|Q00839|HNRPU_HUMAN,tr|A0A1W2PQL0|A0A1W2PQL0_HUMAN,tr|A0A1W2PPL4|A0A1W2PPL4_HUMAN,tr|A0A1W2PQ74|A0A1W2PQ74_HUMAN,tr|Q5RI18|Q5RI18_HUMAN,tr|A0A1W2PP35|A0A1W2PP35_HUMAN,tr|A0A1W2PPS1|A0A1W2PPS1_HUMAN,tr|A0A1W2PRZ7|A0A1W2PRZ7_HUMAN,tr|A0A1W2PPH7|A0A1W2PPH7_HUMAN,tr|A0A1W2PP34|A0A1W2PP34_HUMAN,tr|A0A1X7SBS1|A0A1X7SBS1_HUMAN" 11 4327.7668 4.15 92051 26626 3 4327.754562 1443.5962 Heterogeneous nuclear ribonucleoprotein U OS=Homo sapiens OX=9606 GN=HNRNPU PE=1 SV=6 3.73 3990.6 - 4.79E+06 - - - -2.8236 - 4.85 0.851 - 656.7 1 2 1 -0.0122 36 0 0 0 6.56E+07 1.58E+07 - - - 11.6571 0.9986 221125_WJC_METTL3_EV_vs_WT_F06.26643.26643.3 3.70E-08 17/92 R.K[136.11]DGNASGTTLLEALDC[160.03]ILPPTR[166.11]PT.D "sp|P68104|EF1A1_HUMAN,sp|Q5VTE0|EF1A3_HUMAN,tr|A0A7I2V659|A0A7I2V659_HUMAN,tr|A0A7I2V3H3|A0A7I2V3H3_HUMAN,tr|A0A7I2V5N4|A0A7I2V5N4_HUMAN,tr|A0A087WVQ9|A0A087WVQ9_HUMAN,tr|A0A087WV01|A0A087WV01_HUMAN" 7 2557.3177 0.59 92059 26643 3 2557.314202 853.4465 Elongation factor 1-alpha 1 OS=Homo sapiens OX=9606 GN=EEF1A1 PE=1 SV=1 4.56 3992.9 - 594406 - - - -1.3573 - 3.444 0.591 - 141.2 1 1 0 -0.0035 24 0 0 0 2.89E+06 4.89E+06 - - - 8.0003 1 221125_WJC_METTL3_EV_vs_WT_F06.26647.26647.2 2.51E-07 15/48 R.R[166.11]AEQDSTTVAAFASSLVSGLNSSAS.E "sp|Q86U44|MTA70_HUMAN,tr|F5H6D8|F5H6D8_HUMAN,tr|H0YFV6|H0YFV6_HUMAN,tr|B4DTN4|B4DTN4_HUMAN" 4 2465.1909 0.001 92061 26647 2 2465.20115 1233.6027 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 4.37 3993.4 - 2.42E+06 - - - 4.1392 - 3.092 0.563 - 491 1 1 0 0.0102 25 0 0 0 0.00E+00 1.85E+07 - - - 5.9714 0.9999 221125_WJC_METTL3_EV_vs_WT_F06.26665.26665.4 9.83E-08 37/210 K.DGNASGTTLLEALDC[160.03]ILPPTR[166.11]PTDK[136.11]PLR[166.11]LPLQDVYK[136.11].L "sp|P68104|EF1A1_HUMAN,sp|Q5VTE0|EF1A3_HUMAN,tr|A0A7I2V659|A0A7I2V659_HUMAN,tr|A0A7I2V3H3|A0A7I2V3H3_HUMAN,tr|A0A7I2V5N4|A0A7I2V5N4_HUMAN,tr|A0A087WVQ9|A0A087WVQ9_HUMAN,tr|A0A087WV01|A0A087WV01_HUMAN" 7 4013.1381 0.28 92067 26665 4 4013.134702 1004.2918 Elongation factor 1-alpha 1 OS=Homo sapiens OX=9606 GN=EEF1A1 PE=1 SV=1 4.78 3996 - 3.01E+06 - - - -0.8574 - 4.88 0.613 - 637.5 1 2 1 -0.0034 36 0 0 0 4.42E+07 1.59E+08 - - - 5.0279 0.9999 221125_WJC_METTL3_EV_vs_WT_F06.26667.26667.4 2.24E-07 24/210 K.DGNASGTTLLEALDC[160.03]ILPPTRPTDKPLRLPLQDVYK.L "sp|P68104|EF1A1_HUMAN,sp|Q5VTE0|EF1A3_HUMAN,tr|A0A7I2V659|A0A7I2V659_HUMAN,tr|A0A7I2V3H3|A0A7I2V3H3_HUMAN,tr|A0A7I2V5N4|A0A7I2V5N4_HUMAN,tr|A0A087WVQ9|A0A087WVQ9_HUMAN,tr|A0A087WV01|A0A087WV01_HUMAN" 7 3977.0932 0.28 92069 26667 4 3977.093255 995.2806 Elongation factor 1-alpha 1 OS=Homo sapiens OX=9606 GN=EEF1A1 PE=1 SV=1 4.78 3996.2 - 1.10E+06 - - - 0.0131 - 4.059 0.562 - 211.3 1 2 1 0.0001 36 0 0 0 4.42E+07 1.59E+08 - - - 4.5306 1 221125_WJC_METTL3_EV_vs_WT_F06.26669.26669.3 3.20E-06 Aug-64 K.ATENDIYNFFSPLNPVR.V "sp|P52597|HNRPF_HUMAN,sp|P31943|HNRH1_HUMAN,tr|H0YBD7|H0YBD7_HUMAN,tr|H0YB39|H0YB39_HUMAN,tr|H0YBG7|H0YBG7_HUMAN,tr|E9PCY7|E9PCY7_HUMAN,tr|G8JLB6|G8JLB6_HUMAN" 7 1995.969 2.83 92071 26669 3 1995.969432 666.3303 Heterogeneous nuclear ribonucleoprotein F OS=Homo sapiens OX=9606 GN=HNRNPF PE=1 SV=3 4.37 3996.5 - 312900 - - - 0.1959 - 2.145 0.546 - 69.6 1 2 0 0.0004 17 0 0 0 3.80E+06 1.34E+06 - - - 6.5552 0.94 221125_WJC_METTL3_EV_vs_WT_F06.26673.26673.3 4.97E-06 13/96 R.R[166.11]AEQDSTTVAAFASSLVSGLNSSAS.E "sp|Q86U44|MTA70_HUMAN,tr|F5H6D8|F5H6D8_HUMAN,tr|H0YFV6|H0YFV6_HUMAN,tr|B4DTN4|B4DTN4_HUMAN" 4 2465.1909 0.06 92073 26673 3 2465.200755 822.7376 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 4.37 3997 - 533438 - - - 3.979 - 2.635 0.42 - 100.8 1 1 0 0.0098 25 0 0 0 1.87E+07 3.29E+08 - - - 5.4489 1 221125_WJC_METTL3_EV_vs_WT_F06.26693.26693.4 1.16E-11 15/150 R.DLDELSRYPEDKITPENLPQILLQLK.R "sp|P43243|MATR3_HUMAN,tr|A8MXP9|A8MXP9_HUMAN,tr|D6R991|D6R991_HUMAN,tr|A0A0R4J2E8|A0A0R4J2E8_HUMAN,tr|D6REM6|D6REM6_HUMAN" 5 3079.6441 2.48 92084 26693 4 3079.644336 770.9183 Matrin-3 OS=Homo sapiens OX=9606 GN=MATR3 PE=1 SV=2 4.3 3999.4 - 479474 - - - 0.0662 - 3.072 0.636 - 106.2 1 2 2 0.0002 26 0 0 0 9.01E+06 3.63E+06 - - - 5.1157 1 221125_WJC_METTL3_EV_vs_WT_F06.26697.26697.4 4.08E-10 27/186 R.DSQGHGR[166.11]DLSAAGIGLLAAATQSLSMPASLGR[166.11].M "sp|P43243|MATR3_HUMAN,tr|A0A1B0GX04|A0A1B0GX04_HUMAN,tr|D6RBS2|D6RBS2_HUMAN,tr|A8MXP9|A8MXP9_HUMAN,tr|D6R991|D6R991_HUMAN,tr|D6REK4|D6REK4_HUMAN,tr|D6R9F3|D6R9F3_HUMAN,tr|A0A0R4J2E8|A0A0R4J2E8_HUMAN,tr|D6RB45|D6RB45_HUMAN,tr|D6RCM3|D6RCM3_HUMAN,tr|D6R8Z5|D6R8Z5_HUMAN,tr|D6REM6|D6REM6_HUMAN" 12 3127.5947 1.39 92086 26697 4 3127.593605 782.906 Matrin-3 OS=Homo sapiens OX=9606 GN=MATR3 PE=1 SV=2 6.75 3999.9 - 562683 - - - -0.3613 - 5.437 0.651 - 398.2 1 2 1 -0.0011 32 0 0 0 1.94E+07 1.40E+07 - - - 5.4032 0.9994 221125_WJC_METTL3_EV_vs_WT_F06.26707.26707.4 8.58E-09 22/180 K.MALIQMGSVEEAVQALIDLHNHDLGENHHLR[166.11].V "sp|P26599|PTBP1_HUMAN,tr|A0A0U1RRM4|A0A0U1RRM4_HUMAN,tr|A6NLN1|A6NLN1_HUMAN,tr|A0A0D9SF20|A0A0D9SF20_HUMAN,tr|A0A7I2V621|A0A7I2V621_HUMAN" 5 3499.7328 1.09 92090 26707 4 3500.729983 875.9405 Polypyrimidine tract-binding protein 1 OS=Homo sapiens OX=9606 GN=PTBP1 PE=1 SV=1 5.21 4001.1 - 754982 - - - 284.928 - 4.698 0.615 - 215.1 1 2 0 0.9972 31 0 0 0 1.29E+07 1.18E+07 - - - 4.773 0.8955 221125_WJC_METTL3_EV_vs_WT_F06.26717.26717.3 2.26E-08 24/100 H.NVQPNWITLGNQLDGIHLLDPDVVAR[166.11].F sp|Q86U44|MTA70_HUMAN 1 2906.5278 0.01 92094 26717 3 2907.522771 969.8499 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 4.41 4002.3 - 2.44E+06 - - - 342.3191 - 4.024 0.592 - 330.1 1 1 0 0.995 26 0 0 0 1.05E+06 1.96E+08 - - - 8.0677 1 221125_WJC_METTL3_EV_vs_WT_F06.26723.26723.4 1.61E-08 24/180 K.MALIQMGSVEEAVQALIDLHNHDLGENHHLR.V "sp|P26599|PTBP1_HUMAN,tr|A0A0U1RRM4|A0A0U1RRM4_HUMAN,tr|A6NLN1|A6NLN1_HUMAN,tr|A0A0D9SF20|A0A0D9SF20_HUMAN,tr|A0A7I2V621|A0A7I2V621_HUMAN" 5 3489.7245 1.09 92097 26723 4 3489.729509 873.4384 Polypyrimidine tract-binding protein 1 OS=Homo sapiens OX=9606 GN=PTBP1 PE=1 SV=1 5.21 4003.1 - 728510 - - - 1.4236 - 5.193 0.645 - 273 1 2 0 0.005 31 0 0 0 1.29E+07 1.18E+07 - - - 5.3394 1 221125_WJC_METTL3_EV_vs_WT_F06.26727.26727.3 9.96E-14 25/108 R.AEQDSTTVAAFASSLVSGLNSSASEPAK[136.11].E "sp|Q86U44|MTA70_HUMAN,tr|F5H6D8|F5H6D8_HUMAN,tr|H0YFV6|H0YFV6_HUMAN,tr|B4DTN4|B4DTN4_HUMAN" 4 2732.3232 0.02 92098 26727 3 2733.318267 911.7817 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 4.14 4003.7 - 6.28E+06 - - - 364.1842 - 4.529 0.719 - 499.6 1 2 0 0.9951 28 0 0 0 9.27E+06 4.03E+08 - - - 9.7556 0.8321 221125_WJC_METTL3_EV_vs_WT_F06.26732.26732.3 1.04E-07 21/108 R.R[166.11]AEQDSTTVAAFASSLVSGLNSSASEPA.K "sp|Q86U44|MTA70_HUMAN,tr|F5H6D8|F5H6D8_HUMAN,tr|H0YFV6|H0YFV6_HUMAN,tr|B4DTN4|B4DTN4_HUMAN" 4 2762.3234 0.06 92099 26732 3 2763.317442 921.7817 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 4.14 4004.5 - 5.04E+06 - - - 359.8514 - 3.846 0.569 - 353.9 1 1 0 0.994 28 0 0 0 8.40E+06 1.47E+08 - - - 7.7075 1 221125_WJC_METTL3_EV_vs_WT_F06.26734.26734.2 3.34E-13 17/54 R.AEQDSTTVAAFASSLVSGLNSSASEPAK[136.11].E "sp|Q86U44|MTA70_HUMAN,tr|F5H6D8|F5H6D8_HUMAN,tr|H0YFV6|H0YFV6_HUMAN,tr|B4DTN4|B4DTN4_HUMAN" 4 2732.3232 0.001 92100 26734 2 2733.31901 1367.1689 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 4.14 4004.7 - 752732 - - - 364.4562 - 4.216 0.743 - 480.6 1 2 0 0.9958 28 0 0 0 0.00E+00 1.72E+07 - - - 7.7537 0.8971 221125_WJC_METTL3_EV_vs_WT_F06.26736.26736.4 4.70E-08 28/150 H.NVQPNWITLGNQLDGIHLLDPDVVAR[166.11].F sp|Q86U44|MTA70_HUMAN 1 2906.5278 0.02 92101 26736 4 2907.52678 727.6392 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 4.41 4004.9 - 2.11E+06 - - - 343.6984 - 4.272 0.539 - 302.7 1 1 0 0.999 26 0 0 0 3.29E+05 2.07E+07 - - - 4.0988 1 221125_WJC_METTL3_EV_vs_WT_F06.26743.26743.4 5.36E-09 20/144 K.NYSPYYNTIDDLKDQIVDLTVGNNK.T sp|P35527|K1C9_HUMAN 1 2901.4032 102.93 92103 26743 4 2901.40363 726.3581 "Keratin, type I cytoskeletal 9 OS=Homo sapiens OX=9606 GN=KRT9 PE=1 SV=3" 4.14 4005.8 - 3.54E+06 - - - 0.1368 - 3.192 0.627 - 172 1 2 1 0.0004 25 0 0 0 2.49E+07 2.42E+05 - - - 5.0525 1 221125_WJC_METTL3_EV_vs_WT_F06.26745.26745.3 4.02E-09 19/96 K.NYSPYYNTIDDLKDQIVDLTVGNNK.T sp|P35527|K1C9_HUMAN 1 2901.4032 25.24 92105 26745 3 2901.398992 968.1417 "Keratin, type I cytoskeletal 9 OS=Homo sapiens OX=9606 GN=KRT9 PE=1 SV=3" 4.14 4006 - 1.04E+07 - - - -1.4617 - 3.951 0.679 - 243 1 2 1 -0.0042 25 0 0 0 1.19E+08 4.72E+06 - - - 9.27 0.9997 221125_WJC_METTL3_EV_vs_WT_F06.27413.27413.3 1.52E-05 Aug-52 R.K[136.11]LC[160.03]LNIC[160.03]VGESGDR[166.11].L "sp|P62913|RL11_HUMAN,tr|Q5VVC8|Q5VVC8_HUMAN" 2 1637.7984 1.15 92232 27413 3 1637.792829 546.9401 60S ribosomal protein L11 OS=Homo sapiens OX=9606 GN=RPL11 PE=1 SV=2 6.06 4123.4 - 13892.6 - - - -3.4204 - 1.907 0.506 - 85.8 1 2 0 -0.0056 14 0 0 0 4.80E+05 4.16E+05 - - - 5.8954 0.9956 221125_WJC_METTL3_EV_vs_WT_F07.02398.02398.2 0.00662 12-Sep R.AHESVVK[136.11].S "sp|P13073|COX41_HUMAN,tr|H3BNI5|H3BNI5_HUMAN,tr|Q86WV2|Q86WV2_HUMAN,tr|H3BN72|H3BN72_HUMAN,tr|H3BNV9|H3BNV9_HUMAN" 5 776.4272 0.99 92338 2398 2 776.423996 389.2209 "Cytochrome c oxidase subunit 4 isoform 1, mitochondrial OS=Homo sapiens OX=9606 GN=COX4I1 PE=1 SV=1" 6.79 1179.4 - 9.02E+06 - - - -4.1305 - 1.649 0.345 - 471.1 1 2 0 -0.0032 7 0 0 0 1.53E+08 1.54E+08 - - - 3.173 0.998 221125_WJC_METTL3_EV_vs_WT_F07.02399.02399.2 0.0139 12-Jul R.AHESVVK.S "sp|P13073|COX41_HUMAN,tr|H3BNI5|H3BNI5_HUMAN,tr|Q86WV2|Q86WV2_HUMAN,tr|H3BN72|H3BN72_HUMAN,tr|H3BNV9|H3BNV9_HUMAN" 5 768.413 1.01 92339 2399 2 768.411782 385.2138 "Cytochrome c oxidase subunit 4 isoform 1, mitochondrial OS=Homo sapiens OX=9606 GN=COX4I1 PE=1 SV=1" 6.79 1179.4 - 7.70E+06 - - - -1.589 - 1.587 0.23 - 263.9 1 2 0 -0.0012 7 0 0 0 1.55E+08 1.54E+08 - - - 2.2028 0.9951 221125_WJC_METTL3_EV_vs_WT_F07.02402.02402.2 0.441 12-Jul R.VDC[160.03]NNER.S sp|Q06787|FMR1_HUMAN 1 905.3661 2.2 92342 2402 2 905.362482 453.6903 Synaptic functional regulator FMR1 OS=Homo sapiens OX=9606 GN=FMR1 PE=1 SV=1 4.37 1179.6 - 5.79E+06 - - - -4.0282 - 1.519 0.356 - 180.3 1 2 0 -0.0036 7 0 0 0 3.39E+07 1.54E+07 - - - 2.9939 0.995 221125_WJC_METTL3_EV_vs_WT_F07.02404.02404.2 0.0502 12-Jul K.LNEDK[136.11]PK[136.11].E sp|Q00688|FKBP3_HUMAN 1 858.4782 6.81 92344 2404 2 858.475457 430.2464 Peptidyl-prolyl cis-trans isomerase FKBP3 OS=Homo sapiens OX=9606 GN=FKBP3 PE=1 SV=1 6.07 1179.7 - 3.87E+06 - - - -3.1742 - 1.608 0.248 - 169.7 1 2 0 -0.0027 7 0 0 0 2.05E+08 3.02E+07 - - - 2.3769 0.9941 221125_WJC_METTL3_EV_vs_WT_F07.02405.02405.2 0.0882 12-Jul R.VDC[160.03]NNER[166.11].S sp|Q06787|FMR1_HUMAN 1 915.3744 2.22 92345 2405 2 915.370844 458.6945 Synaptic functional regulator FMR1 OS=Homo sapiens OX=9606 GN=FMR1 PE=1 SV=1 4.37 1179.7 - 3.14E+06 - - - -3.8837 - 1.418 0.347 - 169.5 1 2 0 -0.0036 7 0 0 0 3.35E+07 1.51E+07 - - - 2.7094 0.9973 221125_WJC_METTL3_EV_vs_WT_F07.02406.02406.2 0.0053 14-Aug K.IQQDSGC[160.03]K[136.11].V "sp|Q92945|FUBP2_HUMAN,tr|M0QYH3|M0QYH3_HUMAN,tr|M0R0C6|M0R0C6_HUMAN,tr|M0QXW7|M0QXW7_HUMAN,tr|A0A087WTP3|A0A087WTP3_HUMAN" 5 942.432 1.06 92346 2406 2 942.428454 472.2233 Far upstream element-binding protein 2 OS=Homo sapiens OX=9606 GN=KHSRP PE=1 SV=4 5.83 1179.8 - 2.39E+06 - - - -3.7955 - 1.598 0.403 - 193.1 1 2 0 -0.0036 8 0 0 0 1.19E+08 1.12E+08 - - - 3.4302 0.9958 221125_WJC_METTL3_EV_vs_WT_F07.02413.02413.2 0.825 12-Aug K.KEPVTTR.Q "sp|Q04695|K1C17_HUMAN,tr|F5GWP8|F5GWP8_HUMAN" 2 829.4658 1596.73 92349 2413 2 829.463131 415.7402 "Keratin, type I cytoskeletal 17 OS=Homo sapiens OX=9606 GN=KRT17 PE=1 SV=2" 8.75 1180.6 - 1.03E+07 - - - -3.1779 - 1.692 0.248 - 312.1 1 2 0 -0.0026 7 0 0 0 1.07E+09 6.69E+05 - - - 2.5383 0.9994 221125_WJC_METTL3_EV_vs_WT_F07.02414.02414.2 5.89E-05 14/18 K.AGAHLQGGAK[136.11].R "sp|P04406|G3P_HUMAN,tr|E7EUT5|E7EUT5_HUMAN" 2 916.497 1.15 92350 2414 2 916.49394 459.2558 Glyceraldehyde-3-phosphate dehydrogenase OS=Homo sapiens OX=9606 GN=GAPDH PE=1 SV=3 8.8 1180.6 - 9.88E+06 - - - -3.3541 - 2.375 0.517 - 870.1 1 2 0 -0.0031 10 0 0 0 4.79E+09 4.17E+09 - - - 5.2731 0.9516 221125_WJC_METTL3_EV_vs_WT_F07.02415.02415.2 0.0009 16-Nov A.GAHLQGGAK.R "sp|P04406|G3P_HUMAN,tr|E7EUT5|E7EUT5_HUMAN" 2 837.4457 1.02 92351 2415 2 837.443272 419.7301 Glyceraldehyde-3-phosphate dehydrogenase OS=Homo sapiens OX=9606 GN=GAPDH PE=1 SV=3 8.76 1180.6 - 8.30E+06 - - - -2.8993 - 1.994 0.409 - 479.9 1 1 0 -0.0024 9 0 0 0 4.92E+09 4.84E+09 - - - 4.0577 0.9995 221125_WJC_METTL3_EV_vs_WT_F07.02416.02416.2 5.79E-05 14/18 K.AGAHLQGGAK.R "sp|P04406|G3P_HUMAN,tr|E7EUT5|E7EUT5_HUMAN" 2 908.4828 1.15 92352 2416 2 908.47986 455.2487 Glyceraldehyde-3-phosphate dehydrogenase OS=Homo sapiens OX=9606 GN=GAPDH PE=1 SV=3 8.8 1180.7 - 7.36E+06 - - - -3.2516 - 2.399 0.507 - 865.8 1 2 0 -0.003 10 0 0 0 4.79E+09 4.17E+09 - - - 5.2273 0.911 221125_WJC_METTL3_EV_vs_WT_F07.02417.02417.2 3.05 12-May K.VGHVTER.T "sp|Q14498|RBM39_HUMAN,sp|Q86U06|RBM23_HUMAN,tr|A0A0U1RQW2|A0A0U1RQW2_HUMAN,tr|H0Y4X3|H0Y4X3_HUMAN,tr|H0YJJ3|H0YJJ3_HUMAN,tr|G3XAP0|G3XAP0_HUMAN,tr|A0A0U1RQH7|A0A0U1RQH7_HUMAN,tr|G3V5Z6|G3V5Z6_HUMAN,tr|G3XAC6|G3XAC6_HUMAN" 9 796.4192 1.24 92353 2417 2 796.416898 399.2169 RNA-binding protein 39 OS=Homo sapiens OX=9606 GN=RBM39 PE=1 SV=2 6.72 1180.7 - 4.99E+06 - - - -2.8289 - 0.938 0.162 - 99.5 1 2 0 -0.0023 7 0 0 0 4.00E+07 3.22E+07 - - - 0.034 0.9506 221125_WJC_METTL3_EV_vs_WT_F07.02418.02418.2 0.000692 14-Oct G.AHLQGGAK[136.11].R "sp|P04406|G3P_HUMAN,tr|E7EUT5|E7EUT5_HUMAN" 2 788.4384 1.06 92354 2418 2 788.436662 395.2265 Glyceraldehyde-3-phosphate dehydrogenase OS=Homo sapiens OX=9606 GN=GAPDH PE=1 SV=3 8.8 1180.8 - 1.56E+06 - - - -2.25 - 1.71 0.378 - 386.1 1 1 0 -0.0018 8 0 0 0 6.69E+08 6.29E+08 - - - 3.4504 0.9436 221125_WJC_METTL3_EV_vs_WT_F07.02424.02424.2 0.000349 13/16 A.GAHLQGGAK[136.11].R "sp|P04406|G3P_HUMAN,tr|E7EUT5|E7EUT5_HUMAN" 2 845.4599 1.02 92358 2424 2 845.456824 423.7372 Glyceraldehyde-3-phosphate dehydrogenase OS=Homo sapiens OX=9606 GN=GAPDH PE=1 SV=3 8.76 1181.5 - 3.05E+07 - - - -3.6383 - 2.146 0.456 - 691.3 1 1 0 -0.0031 9 0 0 0 4.92E+09 4.84E+09 - - - 4.6172 0.9974 221125_WJC_METTL3_EV_vs_WT_F07.02425.02425.2 0.0079 14-Jul K.IQQDSGC[160.03]K.V "sp|Q92945|FUBP2_HUMAN,tr|M0QYH3|M0QYH3_HUMAN,tr|M0R0C6|M0R0C6_HUMAN,tr|M0QXW7|M0QXW7_HUMAN,tr|A0A087WTP3|A0A087WTP3_HUMAN" 5 934.4178 1.06 92359 2425 2 934.414818 468.2162 Far upstream element-binding protein 2 OS=Homo sapiens OX=9606 GN=KHSRP PE=1 SV=4 5.83 1181.6 - 6.93E+06 - - - -3.2245 - 1.355 0.416 - 138 1 2 0 -0.003 8 0 0 0 1.19E+08 1.12E+08 - - - 3.0289 0.9925 221125_WJC_METTL3_EV_vs_WT_F07.02429.02429.2 0.0197 14-Aug K.SVSDDSEK.N sp|Q13618|CUL3_HUMAN 1 865.3665 4.05 92363 2429 2 865.363272 433.6905 Cullin-3 OS=Homo sapiens OX=9606 GN=CUL3 PE=1 SV=2 4.03 1182 - 523665 - - - -3.7371 - 1.194 0.381 - 193.9 1 2 0 -0.0032 8 0 0 0 2.88E+07 7.11E+06 - - - 2.3888 0.9478 221125_WJC_METTL3_EV_vs_WT_F07.02432.02432.2 0.00363 14-Sep G.AHLQGGAK.R "sp|P04406|G3P_HUMAN,tr|E7EUT5|E7EUT5_HUMAN" 2 780.4242 1.06 92364 2432 2 780.422114 391.2194 Glyceraldehyde-3-phosphate dehydrogenase OS=Homo sapiens OX=9606 GN=GAPDH PE=1 SV=3 8.8 1182.4 - 7.08E+06 - - - -2.719 - 1.821 0.398 - 356.1 1 1 0 -0.0021 8 0 0 0 6.69E+08 6.29E+08 - - - 3.7877 0.95 221125_WJC_METTL3_EV_vs_WT_F07.02433.02433.2 0.358 14-Jul R.R[166.11]TGC[160.03]IGAK[136.11].H "sp|P62913|RL11_HUMAN,tr|Q5VVC8|Q5VVC8_HUMAN" 2 879.4715 1.38 92365 2433 2 879.46848 440.743 60S ribosomal protein L11 OS=Homo sapiens OX=9606 GN=RPL11 PE=1 SV=2 9.51 1182.5 - 3.84E+06 - - - -3.4805 - 1.42 0.089 - 243.5 1 2 0 -0.0031 8 0 0 0 2.01E+08 1.46E+08 - - - 0.755 0.9984 221125_WJC_METTL3_EV_vs_WT_F07.02450.02450.2 0.0054 16-Nov K.K[136.11]PAAATVTK[136.11].K sp|P16403|H12_HUMAN 1 901.5568 0.47 92374 2450 2 901.553243 451.7857 Histone H1.2 OS=Homo sapiens OX=9606 GN=H1-2 PE=1 SV=2 10 1184.3 - 5.71E+06 - - - -3.9088 - 2.186 0.398 - 333.7 1 2 0 -0.0035 9 0 0 0 1.19E+08 2.50E+08 - - - 4.2421 0.9895 221125_WJC_METTL3_EV_vs_WT_F07.02477.02477.2 0.0143 14-Aug K.VEQDTETK.L sp|Q9NZI8|IF2B1_HUMAN 1 948.44 1.42 92382 2477 2 948.436078 475.2273 Insulin-like growth factor 2 mRNA-binding protein 1 OS=Homo sapiens OX=9606 GN=IGF2BP1 PE=1 SV=2 4.14 1188 - 5.50E+06 - - - -4.1415 - 1.38 0.317 - 249.9 1 2 0 -0.0039 8 0 0 0 1.19E+08 8.37E+07 - - - 2.3525 0.9907 221125_WJC_METTL3_EV_vs_WT_F07.02482.02482.2 0.00732 14-Jul M.GGEQEEER.F sp|Q9Y266|NUDC_HUMAN 1 932.3836 2.34 92385 2482 2 932.380576 467.1991 Nuclear migration protein nudC OS=Homo sapiens OX=9606 GN=NUDC PE=1 SV=1 4.09 1188.5 - 1.95E+06 - - - -3.1929 - 1.648 0.179 - 331.1 1 2 0 -0.003 8 0 0 0 6.38E+07 2.73E+07 - - - 1.8688 0.9158 221125_WJC_METTL3_EV_vs_WT_F07.02483.02483.2 0.000154 16-Sep W.VSSAAQTEK[136.11].G "sp|Q92947|GCDH_HUMAN,tr|K7ERX1|K7ERX1_HUMAN,tr|K7ES74|K7ES74_HUMAN,tr|K7EKH1|K7EKH1_HUMAN,tr|K7ER63|K7ER63_HUMAN" 5 927.4753 1.26 92386 2483 2 927.471652 464.7449 "Glutaryl-CoA dehydrogenase, mitochondrial OS=Homo sapiens OX=9606 GN=GCDH PE=1 SV=1" 5.97 1188.7 - 1.47E+06 - - - -3.9063 - 2.002 0.435 - 218.1 1 1 0 -0.0036 9 0 0 0 1.70E+08 1.35E+08 - - - 4.261 0.828 221125_WJC_METTL3_EV_vs_WT_F07.02487.02487.2 5.15 12-Jun R.AVEEVK[136.11]K[136.11].L "sp|Q96PU8|QKI_HUMAN,tr|F5GYM3|F5GYM3_HUMAN,tr|F5GXS8|F5GXS8_HUMAN,tr|H0YG47|H0YG47_HUMAN,tr|H0YGD6|H0YGD6_HUMAN" 5 817.488 4.48 92388 2487 2 817.484444 409.7513 Protein quaking OS=Homo sapiens OX=9606 GN=QKI PE=1 SV=1 6.19 1189.1 - 2.85E+07 - - - -4.3732 - 1.179 0.097 - 130.3 1 2 0 -0.0036 7 0 0 0 2.51E+09 5.60E+08 - - - 0.2781 0.9814 221125_WJC_METTL3_EV_vs_WT_F07.02489.02489.2 0.067 12-Jul R.EQSTPPK.S "sp|Q92615|LAR4B_HUMAN,tr|A0A087X183|A0A087X183_HUMAN,tr|H0Y4V9|H0Y4V9_HUMAN" 3 785.3919 1.34 92390 2489 2 785.389533 393.7032 La-related protein 4B OS=Homo sapiens OX=9606 GN=LARP4B PE=1 SV=3 6.1 1189.2 - 4.12E+06 - - - -3.0558 - 1.285 0.192 - 236.8 1 2 0 -0.0024 7 0 0 0 1.67E+08 1.24E+08 - - - 1.2529 0.994 221125_WJC_METTL3_EV_vs_WT_F07.02492.02492.2 0.00724 14-Aug K.VEQDTETK[136.11].L sp|Q9NZI8|IF2B1_HUMAN 1 956.4542 1.42 92391 2492 2 956.450841 479.2344 Insulin-like growth factor 2 mRNA-binding protein 1 OS=Homo sapiens OX=9606 GN=IGF2BP1 PE=1 SV=2 4.14 1189.6 - 3.47E+06 - - - -3.5182 - 1.553 0.282 - 205.2 1 2 0 -0.0034 8 0 0 0 1.19E+08 8.38E+07 - - - 2.4504 0.9317 221125_WJC_METTL3_EV_vs_WT_F07.02498.02498.2 0.00206 16-Sep W.VSSAAQTEK.G "sp|Q92947|GCDH_HUMAN,tr|K7ERX1|K7ERX1_HUMAN,tr|K7ES74|K7ES74_HUMAN,tr|K7EKH1|K7EKH1_HUMAN,tr|K7ER63|K7ER63_HUMAN" 5 919.4611 1.26 92395 2498 2 919.457707 460.7378 "Glutaryl-CoA dehydrogenase, mitochondrial OS=Homo sapiens OX=9606 GN=GCDH PE=1 SV=1" 5.97 1190.3 - 7.06E+06 - - - -3.663 - 2.04 0.437 - 229.9 1 1 0 -0.0034 9 0 0 0 1.70E+08 1.35E+08 - - - 4.3302 0.9984 221125_WJC_METTL3_EV_vs_WT_F07.02509.02509.2 0.000899 16-Sep R.SSVATTSGK.A "sp|Q14157|UBP2L_HUMAN,tr|F8W726|F8W726_HUMAN,tr|H7C2T8|H7C2T8_HUMAN,tr|H0Y5H6|H0Y5H6_HUMAN" 4 836.424 1.98 92401 2509 2 836.420555 419.2193 Ubiquitin-associated protein 2-like OS=Homo sapiens OX=9606 GN=UBAP2L PE=1 SV=2 8.47 1191.5 - 5.05E+06 - - - -4.0733 - 1.889 0.468 - 328 1 2 0 -0.0034 9 0 0 0 3.44E+09 1.73E+09 - - - 4.3367 0.9068 221125_WJC_METTL3_EV_vs_WT_F07.02512.02512.2 5.99 12-Jun K.SVTC[160.03]HVK.H "sp|P01876|IGHA1_HUMAN,sp|P01877|IGHA2_HUMAN,tr|A0A286YEY1|A0A286YEY1_HUMAN,tr|A0A0G2JMB2|A0A0G2JMB2_HUMAN,tr|A0A286YEY5|A0A286YEY5_HUMAN" 5 829.4116 0.1 92404 2512 2 829.410211 415.7131 Immunoglobulin heavy constant alpha 1 OS=Homo sapiens OX=9606 GN=IGHA1 PE=1 SV=2 7.97 1191.6 - 1.63E+06 - - - -1.7024 - 0.868 0.123 - 94 1 2 0 -0.0014 7 0 0 0 1.29E+08 1.31E+09 - - - -0.4995 0.9488 221125_WJC_METTL3_EV_vs_WT_F07.02519.02519.2 2.07E-05 20-Sep N.AAGQAGNEAGR.F "sp|Q6UWP8|SBSN_HUMAN,sp|Q6UWP8|SBSN_HUMAN,sp|Q6UWP8|SBSN_HUMAN" 3 1000.4686 96.91 92407 2519 2 1000.465161 501.2416 Suprabasin OS=Homo sapiens OX=9606 GN=SBSN PE=1 SV=2 6.05 1192.5 - 2.07E+06 - - - -3.4574 - 2.175 0.464 - 326.5 1 1 0 -0.0035 11 0 0 0 1.91E+08 1.97E+06 - - - 4.5691 0.9821 221125_WJC_METTL3_EV_vs_WT_F07.02520.02520.2 2.94 12-Jun K.LEGEHER.D "sp|Q5T200|ZC3HD_HUMAN,tr|A0A7I2V4I5|A0A7I2V4I5_HUMAN" 2 868.4039 0.02 92408 2520 2 868.405237 435.2092 Zinc finger CCCH domain-containing protein 13 OS=Homo sapiens OX=9606 GN=ZC3H13 PE=1 SV=1 4.75 1192.6 - 595576 - - - 1.5454 - 1.21 0.13 - 127 1 2 0 0.0013 7 0 0 0 5.62E+07 2.37E+09 - - - 0.6047 0.9728 221125_WJC_METTL3_EV_vs_WT_F07.02527.02527.2 0.572 12-May R.EAPIDK[136.11]K[136.11].G "sp|O14950|ML12B_HUMAN,sp|P19105|ML12A_HUMAN,sp|P24844|MYL9_HUMAN,tr|J3QRS3|J3QRS3_HUMAN" 4 815.4724 3.38 92411 2527 2 815.469806 408.7435 Myosin regulatory light chain 12B OS=Homo sapiens OX=9606 GN=MYL12B PE=1 SV=2 6.17 1193.4 - 4.77E+06 - - - -3.143 - 1.181 0.197 - 128.3 1 2 0 -0.0026 7 0 0 0 2.89E+09 8.53E+08 - - - 1.0224 0.9781 221125_WJC_METTL3_EV_vs_WT_F07.02528.02528.2 1.74 18-Sep R.GLTLAQGGVK.W "tr|A0A0U1RR79|A0A0U1RR79_HUMAN,tr|A0A1B0GVU9|A0A1B0GVU9_HUMAN" 2 942.5498 52.55 92412 2528 2 942.547308 472.2822 Glutamine--tRNA ligase (Fragment) OS=Homo sapiens OX=9606 GN=QARS1 PE=1 SV=1 8.75 1193.4 - 5.11E+06 - - - -2.6768 - 1.455 0.115 - 191.9 1 2 0 -0.0025 10 0 0 0 9.87E+08 1.88E+07 - - - 0.9364 0.8622 221125_WJC_METTL3_EV_vs_WT_F07.02549.02549.2 0.0203 20-Jul D.SPSSSSAGLDK.A "sp|P15408|FOSL2_HUMAN,tr|C9JCN8|C9JCN8_HUMAN" 2 1034.488 999 92423 2549 2 1034.485192 518.2513 Fos-related antigen 2 OS=Homo sapiens OX=9606 GN=FOSL2 PE=1 SV=1 5.55 1196.1 - 630644 - - - -2.7318 - 1.493 0.344 - 154.4 1 1 0 -0.0028 11 0 0 0 1.65E+08 0.00E+00 - - - 2.6651 0.8429 221125_WJC_METTL3_EV_vs_WT_F07.02555.02555.2 4.26 12-Jul K.NEEALKK.C "sp|O75410|TACC1_HUMAN,tr|E7EVI4|E7EVI4_HUMAN,tr|B4E3H6|B4E3H6_HUMAN,tr|H0YAY0|H0YAY0_HUMAN,tr|H0YBT8|H0YBT8_HUMAN,tr|E7ET87|E7ET87_HUMAN" 6 830.4498 2.55 92425 2555 2 830.446096 416.2322 Transforming acidic coiled-coil-containing protein 1 OS=Homo sapiens OX=9606 GN=TACC1 PE=1 SV=2 6.14 1196.9 - 4.57E+06 - - - -4.4386 - 1.122 0.132 - 185.4 1 2 0 -0.0037 7 0 0 0 2.59E+08 1.01E+08 - - - 0.3795 0.9767 221125_WJC_METTL3_EV_vs_WT_F07.02566.02566.2 0.00901 18-Sep K.ASDPGAASTK[136.11].S "sp|Q86VM9|ZCH18_HUMAN,tr|H3BRH3|H3BRH3_HUMAN,tr|E7ERS3|E7ERS3_HUMAN" 3 911.444 1.36 92429 2566 2 911.439692 456.7293 Zinc finger CCCH domain-containing protein 18 OS=Homo sapiens OX=9606 GN=ZC3H18 PE=1 SV=2 5.88 1198.3 - 1.39E+06 - - - -4.6991 - 1.532 0.24 - 127.5 1 2 0 -0.0043 10 0 0 0 7.57E+07 5.57E+07 - - - 2.003 0.9983 221125_WJC_METTL3_EV_vs_WT_F07.02583.02583.2 0.283 20-Dec R.SGATAGAAGGR[166.11].G sp|P50991|TCPD_HUMAN 1 884.434 0.33 92437 2583 2 884.430289 443.2243 T-complex protein 1 subunit delta OS=Homo sapiens OX=9606 GN=CCT4 PE=1 SV=4 9.47 1200.2 - 1.86E+07 - - - -4.1541 - 2.392 0.405 - 621.7 1 2 0 -0.0037 11 0 0 0 1.71E+09 5.24E+09 - - - 4.3905 0.9974 221125_WJC_METTL3_EV_vs_WT_F07.02590.02590.2 3.04E-05 16-Oct K.QDDGTGPEK.L "sp|Q92945|FUBP2_HUMAN,tr|M0R0C6|M0R0C6_HUMAN,tr|A0A087WTP3|A0A087WTP3_HUMAN" 3 945.404 1.38 92440 2590 2 945.399473 473.7093 Far upstream element-binding protein 2 OS=Homo sapiens OX=9606 GN=KHSRP PE=1 SV=4 4.03 1201.1 - 1.95E+06 - - - -4.7398 - 1.891 0.476 - 468.4 1 2 0 -0.0045 9 0 0 0 3.02E+08 2.19E+08 - - - 4.3985 0.9985 221125_WJC_METTL3_EV_vs_WT_F07.02592.02592.2 1.39E-05 20-Dec R.SGATAGAAGGR.G sp|P50991|TCPD_HUMAN 1 874.4257 0.33 92441 2592 2 874.422154 438.2201 T-complex protein 1 subunit delta OS=Homo sapiens OX=9606 GN=CCT4 PE=1 SV=4 9.47 1201.3 - 1.62E+07 - - - -4.0472 - 2.493 0.402 - 594.1 1 2 0 -0.0035 11 0 0 0 1.71E+09 5.25E+09 - - - 4.4803 0.989 221125_WJC_METTL3_EV_vs_WT_F07.02604.02604.2 0.0732 12-Aug R.HLEDANR.A sp|Q96ED9|HOOK2_HUMAN 1 853.4042 2.13 92444 2604 2 853.401563 427.7094 Protein Hook homolog 2 OS=Homo sapiens OX=9606 GN=HOOK2 PE=1 SV=3 5.32 1203 - 1.79E+06 - - - -3.124 - 1.348 0.231 - 164.2 1 2 0 -0.0027 7 0 0 0 5.94E+07 2.78E+07 - - - 1.6925 0.999 221125_WJC_METTL3_EV_vs_WT_F07.02608.02608.2 6.91E-06 16-Oct K.QDDGTGPEK[136.11].L "sp|Q92945|FUBP2_HUMAN,tr|M0R0C6|M0R0C6_HUMAN,tr|A0A087WTP3|A0A087WTP3_HUMAN" 3 953.4182 1.38 92446 2608 2 953.414277 477.7164 Far upstream element-binding protein 2 OS=Homo sapiens OX=9606 GN=KHSRP PE=1 SV=4 4.03 1203.4 - 4.77E+06 - - - -4.0664 - 2.04 0.55 - 520.7 1 2 0 -0.0039 9 0 0 0 3.01E+08 2.19E+08 - - - 5.1647 0.9262 221125_WJC_METTL3_EV_vs_WT_F07.02609.02609.2 1.57 14-Aug K.K[136.11]AGAEVVK[136.11].Q "sp|P54577|SYYC_HUMAN,tr|A0A6Q8PFX4|A0A6Q8PFX4_HUMAN,tr|A0A6Q8PF15|A0A6Q8PF15_HUMAN,tr|A0A0C4DGZ5|A0A0C4DGZ5_HUMAN,tr|A0A6Q8PFX2|A0A6Q8PFX2_HUMAN" 5 816.504 0.64 92447 2609 2 816.499989 409.2593 "Tyrosine--tRNA ligase, cytoplasmic OS=Homo sapiens OX=9606 GN=YARS1 PE=1 SV=4" 8.59 1203.5 - 3.46E+06 - - - -4.9161 - 1.559 0.111 - 191.8 1 2 0 -0.004 8 0 0 0 7.28E+07 1.13E+08 - - - 1.1988 0.9971 221125_WJC_METTL3_EV_vs_WT_F07.02610.02610.2 0.00738 16-Aug K.VGTEC[160.03]GNQK[136.11].V "sp|P21333|FLNA_HUMAN,tr|A0A7P0NMY4|A0A7P0NMY4_HUMAN,tr|Q60FE5|Q60FE5_HUMAN" 3 999.4535 1.03 92448 2610 2 999.450309 500.734 Filamin-A OS=Homo sapiens OX=9606 GN=FLNA PE=1 SV=4 5.97 1203.5 - 4.12E+06 - - - -3.1867 - 1.532 0.357 - 166.2 1 2 0 -0.0032 9 0 0 0 1.17E+08 1.14E+08 - - - 2.9109 0.8332 221125_WJC_METTL3_EV_vs_WT_F07.02615.02615.2 2.64 12-Jul R.K[136.11]VEEVTK[136.11].V "sp|P37198|NUP62_HUMAN,tr|M0QXN5|M0QXN5_HUMAN" 2 847.4986 1.63 92449 2615 2 847.494938 424.7566 Nuclear pore glycoprotein p62 OS=Homo sapiens OX=9606 GN=NUP62 PE=1 SV=3 6.14 1204.3 - 1.39E+07 - - - -4.3009 - 1.305 0.052 - 132.7 1 2 0 -0.0036 7 0 0 0 7.64E+08 4.69E+08 - - - 0.2674 0.9756 221125_WJC_METTL3_EV_vs_WT_F07.02616.02616.2 0.0101 16-Aug K.TANGNVEAK[136.11].V "sp|O94776|MTA2_HUMAN,sp|Q13330|MTA1_HUMAN,tr|H7C3F3|H7C3F3_HUMAN,tr|E7ESY4|E7ESY4_HUMAN" 4 910.46 0.57 92450 2616 2 910.454757 456.2373 Metastasis-associated protein MTA2 OS=Homo sapiens OX=9606 GN=MTA2 PE=1 SV=1 5.66 1204.3 - 1.73E+06 - - - -5.7147 - 1.664 0.281 - 203.7 1 2 0 -0.0052 9 0 0 0 9.31E+07 1.64E+08 - - - 2.588 0.9991 221125_WJC_METTL3_EV_vs_WT_F07.02617.02617.2 8.85E-05 16-Nov K.VGTEC[160.03]GNQK.V "sp|P21333|FLNA_HUMAN,tr|A0A7P0NMY4|A0A7P0NMY4_HUMAN,tr|Q60FE5|Q60FE5_HUMAN" 3 991.4393 0.97 92451 2617 2 991.436105 496.7269 Filamin-A OS=Homo sapiens OX=9606 GN=FLNA PE=1 SV=4 5.97 1204.4 - 5.28E+06 - - - -3.2165 - 2.283 0.392 - 388 1 2 0 -0.0032 9 0 0 0 1.18E+08 1.22E+08 - - - 4.3235 0.8995 221125_WJC_METTL3_EV_vs_WT_F07.02623.02623.2 0.673 14-Jul K.QLEAVSDR.V "sp|Q9Y2Z9|COQ6_HUMAN,tr|G3V3A1|G3V3A1_HUMAN,tr|A0A0D9SFJ1|A0A0D9SFJ1_HUMAN" 3 916.4614 1.95 92454 2623 2 916.458796 459.238 "Ubiquinone biosynthesis monooxygenase COQ6, mitochondrial OS=Homo sapiens OX=9606 GN=COQ6 PE=1 SV=2" 4.37 1205.1 - 1.47E+06 - - - -2.8523 - 1.364 0.016 - 150.9 2 2 0 -0.0026 8 0 0 0 4.83E+07 2.49E+07 - - - -0.0399 0.9745 221125_WJC_METTL3_EV_vs_WT_F07.02632.02632.2 0.918 12-Jul R.KLEDSTR.E sp|P15924|DESP_HUMAN 1 847.4399 0.88 92459 2632 2 847.436995 424.7272 Desmoplakin OS=Homo sapiens OX=9606 GN=DSP PE=1 SV=3 6.07 1206.1 - 9.02E+06 - - - -3.4823 - 1.317 0.181 - 216.7 1 2 0 -0.003 7 0 0 0 2.43E+08 2.77E+08 - - - 1.2494 0.9917 221125_WJC_METTL3_EV_vs_WT_F07.02639.02639.2 0.183 14-Jun K.TQEEGEER.A "sp|Q9NR28|DBLOH_HUMAN,tr|A0A024RBT2|A0A024RBT2_HUMAN" 2 976.4098 1.43 92462 2639 2 976.407822 489.2122 "Diablo homolog, mitochondrial OS=Homo sapiens OX=9606 GN=DIABLO PE=1 SV=1" 4.09 1206.9 - 745854 - - - -1.993 - 1.254 0.212 - 80.1 1 2 0 -0.0019 8 0 0 0 9.83E+06 6.89E+06 - - - 1.2888 0.9678 221125_WJC_METTL3_EV_vs_WT_F07.02646.02646.2 0.202 14-May R.EVSGHSVR.G "sp|Q9NWH9|SLTM_HUMAN,tr|H7C3F4|H7C3F4_HUMAN" 2 869.4355 1.41 92466 2646 2 869.432155 435.725 SAFB-like transcription modulator OS=Homo sapiens OX=9606 GN=SLTM PE=1 SV=2 6.85 1207.6 - 937484 - - - -3.8807 - 1.153 0.293 - 70.4 6 2 0 -0.0034 8 0 0 0 1.67E+07 1.19E+07 - - - 1.2858 0.9972 221125_WJC_METTL3_EV_vs_WT_F07.02651.02651.2 0.003 14-Sep K.VSDEAVKK.D "sp|O75688|PPM1B_HUMAN,tr|B8ZZF0|B8ZZF0_HUMAN,tr|A0A3B3IS24|A0A3B3IS24_HUMAN,tr|C9JIR6|C9JIR6_HUMAN" 4 874.476 0.54 92469 2651 2 874.472437 438.2453 Protein phosphatase 1B OS=Homo sapiens OX=9606 GN=PPM1B PE=1 SV=1 6.04 1208.1 - 2.39E+07 - - - -4.071 - 1.729 0.397 - 214.4 1 2 0 -0.0036 8 0 0 0 1.07E+09 1.99E+09 - - - 3.6235 0.9962 221125_WJC_METTL3_EV_vs_WT_F07.02652.02652.2 0.018 16-Sep K.TANGNVEAK.V "sp|O94776|MTA2_HUMAN,sp|Q13330|MTA1_HUMAN,tr|H7C3F3|H7C3F3_HUMAN,tr|E7ESY4|E7ESY4_HUMAN" 4 902.4458 0.58 92470 2652 2 902.443144 452.2302 Metastasis-associated protein MTA2 OS=Homo sapiens OX=9606 GN=MTA2 PE=1 SV=1 5.66 1208.2 - 3.90E+06 - - - -2.8988 - 1.499 0.304 - 222.6 1 2 0 -0.0026 9 0 0 0 9.15E+07 1.57E+08 - - - 2.4566 0.9864 221125_WJC_METTL3_EV_vs_WT_F07.02659.02659.2 4.72 14-Jul R.LGEQEGK[136.11]R[166.11].S sp|O60684|IMA7_HUMAN 1 933.4999 0.8 92474 2659 2 933.497624 467.7572 Importin subunit alpha-7 OS=Homo sapiens OX=9606 GN=KPNA6 PE=1 SV=1 6.14 1209 - 809945 - - - -2.3996 - 1.327 0.168 - 149.5 1 2 0 -0.0022 8 0 0 0 7.40E+06 9.29E+06 - - - 1.1344 0.9709 221125_WJC_METTL3_EV_vs_WT_F07.02666.02666.2 0.158 12-Jun K.VNPTKPR.R "sp|Q8IZQ5|SELH_HUMAN,tr|H0YE28|H0YE28_HUMAN,tr|A0A087WYP2|A0A087WYP2_HUMAN" 3 810.4712 1.31 92478 2666 2 810.468183 406.2429 Selenoprotein H OS=Homo sapiens OX=9606 GN=SELENOH PE=1 SV=2 11 1209.7 - 910776 - - - -3.7053 - 1.218 0.217 - 194.1 1 2 0 -0.003 7 0 0 0 4.03E+07 3.07E+07 - - - 1.2677 0.9994 221125_WJC_METTL3_EV_vs_WT_F07.02670.02670.2 0.0222 18-Oct K.MENGQSTAAK.L "sp|Q9UHX1|PUF60_HUMAN,tr|A0A0J9YYL3|A0A0J9YYL3_HUMAN,tr|A0A0J9YWM1|A0A0J9YWM1_HUMAN,tr|H0YEM1|H0YEM1_HUMAN,tr|E9PMU7|E9PMU7_HUMAN,tr|E9PN18|E9PN18_HUMAN,tr|E9PL19|E9PL19_HUMAN,tr|A0A0J9YVR6|A0A0J9YVR6_HUMAN,tr|A0A0J9YXX5|A0A0J9YXX5_HUMAN,tr|A0A0J9YXJ8|A0A0J9YXJ8_HUMAN,tr|E9PQ56|E9PQ56_HUMAN,tr|A0A0J9YVP6|A0A0J9YVP6_HUMAN" 12 1035.4655 1.15 92479 2670 2 1035.46446 518.74 Poly(U)-binding-splicing factor PUF60 OS=Homo sapiens OX=9606 GN=PUF60 PE=1 SV=1 5.75 1210.3 - 826788 - - - -1.0131 - 1.549 0.367 - 286.7 1 2 0 -0.001 10 0 0 0 4.18E+07 3.63E+07 - - - 2.9728 0.9197 221125_WJC_METTL3_EV_vs_WT_F07.02676.02676.2 4.78 12-May K.ESESVDK.V "sp|Q14103|HNRPD_HUMAN,tr|H0Y8G5|H0Y8G5_HUMAN,tr|D6RF44|D6RF44_HUMAN,tr|D6RBQ9|D6RBQ9_HUMAN,tr|D6RAF8|D6RAF8_HUMAN,tr|H0YA96|H0YA96_HUMAN" 6 792.3501 1.39 92483 2676 2 792.347796 397.1823 Heterogeneous nuclear ribonucleoprotein D0 OS=Homo sapiens OX=9606 GN=HNRNPD PE=1 SV=1 4.14 1210.9 - 2.23E+07 - - - -2.9431 - 1.082 0.118 - 144.4 1 2 0 -0.0023 7 0 0 0 5.69E+08 4.11E+08 - - - 0.1615 0.991 221125_WJC_METTL3_EV_vs_WT_F07.02680.02680.2 0.5 12-Jul K.ESESVDK[136.11].V "sp|Q14103|HNRPD_HUMAN,tr|H0Y8G5|H0Y8G5_HUMAN,tr|D6RF44|D6RF44_HUMAN,tr|D6RBQ9|D6RBQ9_HUMAN,tr|D6RAF8|D6RAF8_HUMAN,tr|H0YA96|H0YA96_HUMAN" 6 800.3643 1.39 92486 2680 2 800.361738 401.1894 Heterogeneous nuclear ribonucleoprotein D0 OS=Homo sapiens OX=9606 GN=HNRNPD PE=1 SV=1 4.14 1211.3 - 2.10E+07 - - - -3.236 - 1.389 0.249 - 301.4 1 2 0 -0.0026 7 0 0 0 5.69E+08 4.11E+08 - - - 1.9204 0.9989 221125_WJC_METTL3_EV_vs_WT_F07.02682.02682.2 0.00109 14-Nov R.HLTASEAK.K sp|P39748|FEN1_HUMAN 1 855.445 0.42 92487 2682 2 855.44247 428.7298 Flap endonuclease 1 OS=Homo sapiens OX=9606 GN=FEN1 PE=1 SV=1 6.75 1211.5 - 6.72E+06 - - - -2.9938 - 2.201 0.33 - 444.8 1 2 0 -0.0026 8 0 0 0 2.13E+08 5.07E+08 - - - 3.8569 0.9991 221125_WJC_METTL3_EV_vs_WT_F07.02686.02686.2 0.0223 14-Aug K.TSDVTSTK.G "sp|P26196|DDX6_HUMAN,tr|Q8IV96|Q8IV96_HUMAN" 2 837.408 0.94 92489 2686 2 837.406231 419.7113 Probable ATP-dependent RNA helicase DDX6 OS=Homo sapiens OX=9606 GN=DDX6 PE=1 SV=2 5.5 1212 - 3.58E+06 - - - -2.085 - 1.654 0.372 - 267.4 1 2 0 -0.0017 8 0 0 0 5.08E+08 5.43E+08 - - - 3.3057 0.9766 221125_WJC_METTL3_EV_vs_WT_F07.02695.02695.2 0.776 12-Aug K.KALPPEK.K "sp|Q00839|HNRPU_HUMAN,tr|A0A1W2PQL0|A0A1W2PQL0_HUMAN,tr|A0A1W2PPL4|A0A1W2PPL4_HUMAN,tr|A0A087WZF3|A0A087WZF3_HUMAN,tr|Q5RI18|Q5RI18_HUMAN,tr|A0A1W2PP35|A0A1W2PP35_HUMAN,tr|A0A1W2PPS1|A0A1W2PPS1_HUMAN,tr|A0A1W2PPH7|A0A1W2PPH7_HUMAN,tr|A0A1W2PQD4|A0A1W2PQD4_HUMAN,tr|A0A1W2PP34|A0A1W2PP34_HUMAN,tr|A0A1X7SBS1|A0A1X7SBS1_HUMAN" 11 781.4698 1.07 92494 2695 2 781.467263 391.7422 Heterogeneous nuclear ribonucleoprotein U OS=Homo sapiens OX=9606 GN=HNRNPU PE=1 SV=6 8.59 1213 - 2.61E+06 - - - -3.2337 - 1.246 0.195 - 261.8 1 2 0 -0.0025 7 0 0 0 8.42E+07 7.86E+07 - - - 1.1774 0.9991 221125_WJC_METTL3_EV_vs_WT_F07.02699.02699.2 0.0493 14-Sep K.TSDVTSTK[136.11].G "sp|P26196|DDX6_HUMAN,tr|Q8IV96|Q8IV96_HUMAN" 2 845.4222 1.09 92495 2699 2 845.420396 423.7184 Probable ATP-dependent RNA helicase DDX6 OS=Homo sapiens OX=9606 GN=DDX6 PE=1 SV=2 5.5 1213.6 - 1.41E+07 - - - -2.1066 - 2.01 0.284 - 352.4 1 2 0 -0.0018 8 0 0 0 5.07E+08 4.66E+08 - - - 3.2436 0.9976 221125_WJC_METTL3_EV_vs_WT_F07.02700.02700.2 0.000396 14-Aug K.YVDEASK[136.11]K[136.11].E "sp|P62249|RS16_HUMAN,tr|M0R210|M0R210_HUMAN" 2 954.4993 0.71 92496 2700 2 954.496483 478.2569 40S ribosomal protein S16 OS=Homo sapiens OX=9606 GN=RPS16 PE=1 SV=2 6.07 1213.7 - 611599 - - - -2.9639 - 1.518 0.358 - 175.1 1 2 0 -0.0028 8 0 0 0 5.69E+08 8.01E+08 - - - 2.9431 0.9902 221125_WJC_METTL3_EV_vs_WT_F07.02713.02713.2 0.00281 14-Sep K.YVDEASKK.E "sp|P62249|RS16_HUMAN,tr|M0R210|M0R210_HUMAN" 2 938.4709 0.71 92503 2713 2 938.467681 470.2427 40S ribosomal protein S16 OS=Homo sapiens OX=9606 GN=RPS16 PE=1 SV=2 6.07 1215.2 - 4.17E+06 - - - -3.4428 - 1.381 0.265 - 210 1 2 0 -0.0032 8 0 0 0 5.69E+08 8.01E+08 - - - 1.9708 0.9963 221125_WJC_METTL3_EV_vs_WT_F07.02715.02715.2 0.776 12-Aug K.K[136.11]FVSGQK[136.11].S sp|P22695|QCR2_HUMAN 1 808.4778 1.77 92505 2715 2 808.475864 405.2462 "Cytochrome b-c1 complex subunit 2, mitochondrial OS=Homo sapiens OX=9606 GN=UQCRC2 PE=1 SV=3" 10 1215.3 - 1.98E+06 - - - -2.3798 - 1.51 0.242 - 265.1 1 2 0 -0.0019 7 0 0 0 1.10E+08 6.21E+07 - - - 2.1336 0.9916 221125_WJC_METTL3_EV_vs_WT_F07.02721.02721.2 0.0779 12-Jul K.K[136.11]ALPPEK[136.11].K "sp|Q00839|HNRPU_HUMAN,tr|A0A1W2PQL0|A0A1W2PQL0_HUMAN,tr|A0A1W2PPL4|A0A1W2PPL4_HUMAN,tr|A0A087WZF3|A0A087WZF3_HUMAN,tr|Q5RI18|Q5RI18_HUMAN,tr|A0A1W2PP35|A0A1W2PP35_HUMAN,tr|A0A1W2PPS1|A0A1W2PPS1_HUMAN,tr|A0A1W2PPH7|A0A1W2PPH7_HUMAN,tr|A0A1W2PQD4|A0A1W2PQD4_HUMAN,tr|A0A1W2PP34|A0A1W2PP34_HUMAN,tr|A0A1X7SBS1|A0A1X7SBS1_HUMAN" 11 797.4982 1.04 92509 2721 2 797.496264 399.7564 Heterogeneous nuclear ribonucleoprotein U OS=Homo sapiens OX=9606 GN=HNRNPU PE=1 SV=6 8.59 1216 - 3.45E+06 - - - -2.4151 - 1.451 0.174 - 202.9 1 2 0 -0.0019 7 0 0 0 3.23E+08 3.10E+08 - - - 1.5051 0.8132 221125_WJC_METTL3_EV_vs_WT_F07.02726.02726.2 0.104 16-Sep Y.AAQTSPSPK[136.11].A "sp|P06576|ATPB_HUMAN,tr|F8W0P7|F8W0P7_HUMAN" 2 893.4698 1.76 92512 2726 2 893.466772 447.7422 "ATP synthase subunit beta, mitochondrial OS=Homo sapiens OX=9606 GN=ATP5F1B PE=1 SV=3" 8.8 1216.5 - 1.48E+07 - - - -3.3846 - 1.793 0.277 - 402.4 1 1 0 -0.003 9 0 0 0 1.59E+09 9.00E+08 - - - 2.7752 0.7637 221125_WJC_METTL3_EV_vs_WT_F07.02728.02728.2 0.197 12-Jul Y.VDEASK[136.11]K[136.11].E "sp|P62249|RS16_HUMAN,tr|M0R210|M0R210_HUMAN" 2 791.436 0.64 92514 2728 2 791.433896 396.7253 40S ribosomal protein S16 OS=Homo sapiens OX=9606 GN=RPS16 PE=1 SV=2 6.04 1216.6 - 9.58E+06 - - - -2.637 - 1.438 0.248 - 151.6 1 1 0 -0.0021 7 0 0 0 1.56E+08 2.42E+08 - - - 2.0231 0.9769 221125_WJC_METTL3_EV_vs_WT_F07.02729.02729.2 0.31 14-May K.SQETPATK.K "sp|P09012|SNRPA_HUMAN,tr|M0QZG7|M0QZG7_HUMAN,tr|M0R2B8|M0R2B8_HUMAN,tr|M0R221|M0R221_HUMAN,tr|M0QXK2|M0QXK2_HUMAN,tr|M0R268|M0R268_HUMAN" 6 860.424 1.09 92515 2729 2 860.421479 431.2193 U1 small nuclear ribonucleoprotein A OS=Homo sapiens OX=9606 GN=SNRPA PE=1 SV=3 5.72 1216.7 - 4.71E+06 - - - -2.8858 - 1.085 0.251 - 81.2 2 2 0 -0.0025 8 0 0 0 2.67E+08 2.46E+08 - - - 1.0057 0.997 221125_WJC_METTL3_EV_vs_WT_F07.02735.02735.2 0.224 16-Sep K.DTDVGGGGK.G sp|Q96F45|ZN503_HUMAN 1 804.3614 1.05 92519 2735 2 804.359296 403.188 Zinc finger protein 503 OS=Homo sapiens OX=9606 GN=ZNF503 PE=1 SV=1 4.21 1217.3 - 5.80E+06 - - - -2.5673 - 1.644 0.267 - 334.5 1 2 0 -0.0021 9 0 0 0 1.17E+08 1.11E+08 - - - 2.4506 0.996 221125_WJC_METTL3_EV_vs_WT_F07.02737.02737.2 1.03 14-Jul K.YVDEASK[136.11]K.E "sp|P62249|RS16_HUMAN,tr|M0R210|M0R210_HUMAN" 2 946.4851 - 92521 2737 2 946.483461 474.2498 40S ribosomal protein S16 OS=Homo sapiens OX=9606 GN=RPS16 PE=1 SV=2 6.07 1217.4 - 1.12E+06 - - - -1.7443 - 1.423 0.218 - 102.1 1 2 0 -0.0017 8 0 0 0 - - - - - 1.7146 0.9991 221125_WJC_METTL3_EV_vs_WT_F07.02738.02738.2 9.69E-06 14/16 K.MLQHAASNK.M "sp|P46940|IQGA1_HUMAN,tr|H0YLE8|H0YLE8_HUMAN" 2 998.4967 0.49 92522 2738 2 998.493013 500.2557 Ras GTPase-activating-like protein IQGAP1 OS=Homo sapiens OX=9606 GN=IQGAP1 PE=1 SV=1 8.52 1217.6 - 960303 - - - -3.7416 - 2.222 0.48 - 820.7 1 2 0 -0.0037 9 0 0 0 8.65E+06 1.75E+07 - - - 4.8949 0.9932 221125_WJC_METTL3_EV_vs_WT_F07.02744.02744.2 0.00952 16-Aug K.DTDVGGGGK[136.11].G sp|Q96F45|ZN503_HUMAN 1 812.3756 1.05 92524 2744 2 812.373094 407.1951 Zinc finger protein 503 OS=Homo sapiens OX=9606 GN=ZNF503 PE=1 SV=1 4.21 1218.4 - 4.18E+06 - - - -3.0368 - 1.569 0.228 - 300.1 1 2 0 -0.0025 9 0 0 0 1.17E+08 1.11E+08 - - - 2.0274 0.9918 221125_WJC_METTL3_EV_vs_WT_F07.02746.02746.2 0.663 12-Jun K.SLETEHK.A "sp|P04843|RPN1_HUMAN,tr|B7Z4L4|B7Z4L4_HUMAN" 2 842.4134 1.05 92526 2746 2 842.41129 422.214 Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit 1 OS=Homo sapiens OX=9606 GN=RPN1 PE=1 SV=1 5.38 1218.5 - 7.77E+06 - - - -2.5011 - 1.276 0.238 - 104.3 1 2 0 -0.0021 7 0 0 0 2.24E+08 2.13E+08 - - - 1.5705 0.9981 221125_WJC_METTL3_EV_vs_WT_F07.02757.02757.2 0.155 18-Dec K.QAESASEAAK[136.11].K "sp|P51572|BAP31_HUMAN,tr|A0A2R8Y5M6|A0A2R8Y5M6_HUMAN,tr|C9J0M4|C9J0M4_HUMAN,tr|C9JQ75|C9JQ75_HUMAN,tr|C9JSP1|C9JSP1_HUMAN,tr|C9JMD7|C9JMD7_HUMAN" 6 998.476 1.11 92531 2757 2 998.47144 500.2453 B-cell receptor-associated protein 31 OS=Homo sapiens OX=9606 GN=BCAP31 PE=1 SV=3 4.53 1219.8 - 3.73E+06 - - - -4.571 - 2.426 0.428 - 768 1 2 0 -0.0046 10 0 0 0 3.39E+08 3.06E+08 - - - 4.6746 0.9982 221125_WJC_METTL3_EV_vs_WT_F07.02758.02758.2 0.11 14-Aug R.QAQEEAER.L sp|Q15149|PLEC_HUMAN 1 959.4308 2.3 92532 2758 2 959.427089 480.7227 Plectin OS=Homo sapiens OX=9606 GN=PLEC PE=1 SV=3 4.25 1219.8 - 2.04E+06 - - - -3.9075 - 1.784 0.436 - 392.6 1 2 0 -0.0037 8 0 0 0 3.95E+07 1.72E+07 - - - 4.0059 0.9994 221125_WJC_METTL3_EV_vs_WT_F07.02767.02767.2 0.0631 16-Aug K.VQAAQSEAK[136.11].V "sp|Q16891|MIC60_HUMAN,tr|B9A067|B9A067_HUMAN,tr|C9J406|C9J406_HUMAN,tr|H7C463|H7C463_HUMAN" 4 938.4913 2.83 92537 2767 2 938.49143 470.2529 MICOS complex subunit MIC60 OS=Homo sapiens OX=9606 GN=IMMT PE=1 SV=1 5.97 1220.9 - 1.96E+07 - - - 0.1811 - 1.775 0.296 - 185 1 2 0 0.0002 9 0 0 0 6.28E+08 2.22E+08 - - - 2.8872 0.9769 221125_WJC_METTL3_EV_vs_WT_F07.02778.02778.2 0.269 12-Jul R.KLTAEQR.K sp|O43395|PRPF3_HUMAN 1 844.4767 2.4 92544 2778 2 844.473838 423.2456 U4\U6 small nuclear ribonucleoprotein Prp3 OS=Homo sapiens OX=9606 GN=PRPF3 PE=1 SV=2 8.75 1222 - 4.79E+06 - - - -3.3488 - 1.759 0.057 - 246 1 2 0 -0.0028 7 0 0 0 6.11E+08 2.54E+08 - - - 1.2505 0.9988 221125_WJC_METTL3_EV_vs_WT_F07.02784.02784.2 0.0039 14-Aug K.VTEGQQER[166.11].L sp|Q13263|TIF1B_HUMAN 1 955.4598 0.86 92545 2784 2 955.458607 478.7372 Transcription intermediary factor 1-beta OS=Homo sapiens OX=9606 GN=TRIM28 PE=1 SV=5 4.53 1222.9 - 1.34E+06 - - - -1.2936 - 1.613 0.269 - 257.2 1 2 0 -0.0012 8 0 0 0 3.76E+08 4.36E+08 - - - 2.4694 0.9975 221125_WJC_METTL3_EV_vs_WT_F07.02785.02785.2 0.00633 14-Sep R.NPSC[160.03]EDGR[166.11].L sp|Q7L2J0|MEPCE_HUMAN 1 943.3693 1.07 92546 2785 2 943.365332 472.6919 7SK snRNA methylphosphate capping enzyme OS=Homo sapiens OX=9606 GN=MEPCE PE=1 SV=1 4.37 1223 - 1.43E+06 - - - -4.221 - 1.361 0.531 - 252.8 1 2 0 -0.004 8 0 0 0 1.28E+07 1.20E+07 - - - 3.8913 0.9992 221125_WJC_METTL3_EV_vs_WT_F07.02789.02789.2 0.00312 18-Sep K.QAESASEAAK.K "sp|P51572|BAP31_HUMAN,tr|A0A2R8Y5M6|A0A2R8Y5M6_HUMAN,tr|C9J0M4|C9J0M4_HUMAN,tr|C9JQ75|C9JQ75_HUMAN,tr|C9JSP1|C9JSP1_HUMAN,tr|C9JMD7|C9JMD7_HUMAN" 6 990.4618 1.11 92548 2789 2 990.458606 496.2382 B-cell receptor-associated protein 31 OS=Homo sapiens OX=9606 GN=BCAP31 PE=1 SV=3 4.53 1223.5 - 1.53E+07 - - - -3.2288 - 2.202 0.428 - 282.5 1 2 0 -0.0032 10 0 0 0 3.39E+08 3.06E+08 - - - 4.4046 0.977 221125_WJC_METTL3_EV_vs_WT_F07.02790.02790.2 0.343 12-Aug R.K[136.11]LTAEQR[166.11].K sp|O43395|PRPF3_HUMAN 1 862.4991 2.36 92549 2790 2 862.496443 432.2568 U4\U6 small nuclear ribonucleoprotein Prp3 OS=Homo sapiens OX=9606 GN=PRPF3 PE=1 SV=2 8.75 1223.6 - 9.32E+06 - - - -3.1223 - 1.756 0.042 - 325.5 1 2 0 -0.0027 7 0 0 0 6.00E+08 2.54E+08 - - - 1.1344 0.8267 221125_WJC_METTL3_EV_vs_WT_F07.02799.02799.2 0.928 14-Jun K.VQSVSQNK[136.11].S sp|Q9UMY1|NOL7_HUMAN 1 896.4807 0.9 92554 2799 2 896.476835 449.2476 Nucleolar protein 7 OS=Homo sapiens OX=9606 GN=NOL7 PE=1 SV=2 8.72 1224.5 - 6.01E+06 - - - -4.3057 - 1.215 0.083 - 93.9 1 2 0 -0.0039 8 0 0 0 1.48E+08 1.63E+08 - - - 0.2402 0.9957 221125_WJC_METTL3_EV_vs_WT_F07.02803.02803.2 0.00147 14-Aug K.VTEGQQER.L sp|Q13263|TIF1B_HUMAN 1 945.4516 0.86 92557 2803 2 945.448636 473.7331 Transcription intermediary factor 1-beta OS=Homo sapiens OX=9606 GN=TRIM28 PE=1 SV=5 4.53 1224.9 - 6.14E+06 - - - -3.1065 - 1.727 0.242 - 287.5 1 2 0 -0.0029 8 0 0 0 3.81E+08 4.42E+08 - - - 2.4754 0.9862 221125_WJC_METTL3_EV_vs_WT_F07.02804.02804.2 0.0342 18-Jun K.R[166.11]AAVAASSSS.- sp|P61927|RL37_HUMAN 1 915.4649 0.67 92558 2804 2 915.461636 458.7397 60S ribosomal protein L37 OS=Homo sapiens OX=9606 GN=RPL37 PE=1 SV=2 9.75 1224.9 - 3.11E+06 - - - -3.5971 - 1.347 0.259 - 171.1 1 2 0 -0.0033 10 0 0 0 2.10E+08 3.11E+08 - - - 1.7844 0.9963 221125_WJC_METTL3_EV_vs_WT_F07.02812.02812.2 0.0101 14-Aug K.QSAESVSK.G "sp|O43615|TIM44_HUMAN,tr|M0QXU7|M0QXU7_HUMAN" 2 834.4083 1.13 92564 2812 2 834.405733 418.2114 Mitochondrial import inner membrane translocase subunit TIM44 OS=Homo sapiens OX=9606 GN=TIMM44 PE=1 SV=2 6 1225.7 - 2.42E+06 - - - -3.0896 - 1.498 0.316 - 361.6 1 2 0 -0.0026 8 0 0 0 7.26E+08 6.45E+08 - - - 2.593 0.9276 221125_WJC_METTL3_EV_vs_WT_F07.02840.02840.2 0.00404 16-Oct T.QATETTTTR.H sp|Q14677|EPN4_HUMAN 1 1007.4884 1.5 92577 2840 2 1007.484374 504.7515 Clathrin interactor 1 OS=Homo sapiens OX=9606 GN=CLINT1 PE=1 SV=1 6 1229 - 2.29E+06 - - - -3.9494 - 2.175 0.443 - 550.4 1 1 0 -0.004 9 0 0 0 5.45E+07 3.63E+07 - - - 4.5597 0.8975 221125_WJC_METTL3_EV_vs_WT_F07.02842.02842.2 0.000277 16-Sep T.QATETTTTR[166.11].H sp|Q14677|EPN4_HUMAN 1 1017.4966 1.5 92579 2842 2 1017.4925 509.7556 Clathrin interactor 1 OS=Homo sapiens OX=9606 GN=CLINT1 PE=1 SV=1 6 1229.2 - 1.53E+06 - - - -4.0521 - 1.79 0.458 - 252.8 1 1 0 -0.0041 9 0 0 0 5.45E+07 3.63E+07 - - - 4.1069 0.7862 221125_WJC_METTL3_EV_vs_WT_F07.02861.02861.2 0.123 14-Jul R.DVTNNQEK[136.11].H "sp|Q9Y2L1|RRP44_HUMAN,tr|F2Z2C0|F2Z2C0_HUMAN" 2 954.4498 0.32 92590 2861 2 954.443349 478.2322 Exosome complex exonuclease RRP44 OS=Homo sapiens OX=9606 GN=DIS3 PE=1 SV=2 4.37 1231.5 - 2.43E+06 - - - -6.7473 - 1.273 0.198 - 115.2 1 2 0 -0.0064 8 0 0 0 8.69E+07 2.71E+08 - - - 1.2294 0.8799 221125_WJC_METTL3_EV_vs_WT_F07.02862.02862.2 4.36 16-Jun R.EADVEPMVS.- "sp|Q5TF58|IFFO2_HUMAN,tr|J3KNZ4|J3KNZ4_HUMAN,tr|H0Y4W3|H0Y4W3_HUMAN" 3 975.4219 - 92591 2862 2 975.42179 488.7182 Intermediate filament family orphan 2 OS=Homo sapiens OX=9606 GN=IFFO2 PE=2 SV=3 3.57 1231.6 - 935592 - - - -0.1261 - 0.954 0.038 - 114 3 2 0 -0.0001 9 0 0 0 - - - - - -1.0277 0.9992 221125_WJC_METTL3_EV_vs_WT_F07.02864.02864.2 3.50E-05 18-Sep R.GVSSESSGDR[166.11].E "sp|Q13435|SF3B2_HUMAN,tr|E9PPJ0|E9PPJ0_HUMAN,tr|H0YCG1|H0YCG1_HUMAN,tr|E9PJ04|E9PJ04_HUMAN" 4 989.4289 0.93 92593 2864 2 989.425419 495.7217 Splicing factor 3B subunit 2 OS=Homo sapiens OX=9606 GN=SF3B2 PE=1 SV=2 4.37 1231.8 - 693538 - - - -3.5556 - 1.981 0.541 - 225.6 1 2 0 -0.0035 10 0 0 0 1.91E+07 2.06E+07 - - - 4.9439 0.9996 221125_WJC_METTL3_EV_vs_WT_F07.02875.02875.2 0.0653 16-Oct K.EQAAQEAEK.Q sp|P50219|MNX1_HUMAN 1 1002.4618 1.8 92598 2875 2 1002.46133 502.2382 Motor neuron and pancreas homeobox protein 1 OS=Homo sapiens OX=9606 GN=MNX1 PE=1 SV=3 4.25 1233.2 - 553322 - - - -0.4728 - 1.709 0.358 - 482.9 1 2 0 -0.0005 9 0 0 0 1.79E+08 9.92E+07 - - - 3.2355 0.9734 221125_WJC_METTL3_EV_vs_WT_F07.02882.02882.2 0.214 12-May R.VPDHHPC[160.03].- sp|P78371|TCPB_HUMAN 1 860.3599 - 92601 2882 2 860.35809 431.1872 T-complex protein 1 subunit beta OS=Homo sapiens OX=9606 GN=CCT2 PE=1 SV=4 5.96 1234.1 - 1.02E+07 - - - -2.1293 - 1.011 0.197 - 114.9 1 2 0 -0.0018 7 0 0 0 - - - - - 0.5301 0.9965 221125_WJC_METTL3_EV_vs_WT_F07.02884.02884.2 0.000457 14-Jul K.AQAAEPNR[166.11].G sp|Q9Y6J9|TAF6L_HUMAN 1 865.4281 1.2 92603 2884 2 865.426106 433.7214 TAF6-like RNA polymerase II p300\CBP-associated factor-associated factor 65 kDa subunit 6L OS=Homo sapiens OX=9606 GN=TAF6L PE=1 SV=1 6.05 1234.2 - 2.66E+06 - - - -2.3607 - 1.643 0.222 - 310.5 1 2 0 -0.002 8 0 0 0 1.07E+08 8.91E+07 - - - 2.1775 0.9973 221125_WJC_METTL3_EV_vs_WT_F07.02890.02890.2 0.134 12-Aug K.AVEHINK.T "sp|P06733|ENOA_HUMAN,tr|K7ERS8|K7ERS8_HUMAN,tr|K7EM90|K7EM90_HUMAN,tr|A0A2R8Y879|A0A2R8Y879_HUMAN,tr|A0A2R8Y6I8|A0A2R8Y6I8_HUMAN,tr|A0A2R8YEM5|A0A2R8YEM5_HUMAN" 6 809.4396 1.39 92607 2890 2 809.438656 405.7271 Alpha-enolase OS=Homo sapiens OX=9606 GN=ENO1 PE=1 SV=2 6.79 1234.7 - 3.04E+06 - - - -1.1069 - 1.473 0.2 - 227.5 1 2 0 -0.0009 7 0 0 0 9.98E+08 7.20E+08 - - - 1.7451 0.9793 221125_WJC_METTL3_EV_vs_WT_F07.02891.02891.2 0.103 12-Jul K.AVEHINK[136.11].T "sp|P06733|ENOA_HUMAN,tr|K7ERS8|K7ERS8_HUMAN,tr|K7EM90|K7EM90_HUMAN,tr|A0A2R8Y879|A0A2R8Y879_HUMAN,tr|A0A2R8Y6I8|A0A2R8Y6I8_HUMAN,tr|A0A2R8YEM5|A0A2R8YEM5_HUMAN" 6 817.4538 1.43 92608 2891 2 817.451549 409.7342 Alpha-enolase OS=Homo sapiens OX=9606 GN=ENO1 PE=1 SV=2 6.79 1234.8 - 2.93E+06 - - - -2.695 - 1.209 0.182 - 173 1 2 0 -0.0022 7 0 0 0 9.98E+08 6.98E+08 - - - 0.9859 0.9994 221125_WJC_METTL3_EV_vs_WT_F07.02892.02892.2 0.00698 16-Oct K.EQAAQEAEK[136.11].Q sp|P50219|MNX1_HUMAN 1 1010.476 1.8 92609 2892 2 1010.473932 506.2453 Motor neuron and pancreas homeobox protein 1 OS=Homo sapiens OX=9606 GN=MNX1 PE=1 SV=3 4.25 1234.9 - 2.72E+06 - - - -2.0505 - 1.822 0.387 - 459.9 1 2 0 -0.0021 9 0 0 0 1.79E+08 9.92E+07 - - - 3.6344 0.9089 221125_WJC_METTL3_EV_vs_WT_F07.02898.02898.2 0.00666 14-Jul K.QSHGAAPC[160.03].S "sp|Q86SG5|S1A7A_HUMAN,sp|P31151|S10A7_HUMAN" 2 826.3392 - 92612 2898 2 826.33727 414.1769 Protein S100-A7A OS=Homo sapiens OX=9606 GN=S100A7A PE=1 SV=3 6.73 1235.6 - 2.99E+06 - - - -2.3187 - 1.186 0.442 - 198.2 1 1 0 -0.0019 8 0 0 0 - - - - - 2.8195 0.982 221125_WJC_METTL3_EV_vs_WT_F07.02900.02900.2 1.62 14-Jun R.AQQQLNSK[136.11].L sp|Q9H2G2|SLK_HUMAN 1 923.4916 1.17 92613 2900 2 923.489265 462.7531 STE20-like serine\threonine-protein kinase OS=Homo sapiens OX=9606 GN=SLK PE=1 SV=1 8.8 1235.8 - 1.47E+06 - - - -2.522 - 1.4 0.128 - 183.1 1 2 0 -0.0023 8 0 0 0 3.78E+07 3.24E+07 - - - 1.0005 0.9782 221125_WJC_METTL3_EV_vs_WT_F07.02902.02902.2 0.0676 12-Jun R.HTMDGPR[166.11].Q sp|Q7LGA3|HS2ST_HUMAN 1 822.3682 1.13 92614 2902 2 822.365658 412.1914 Heparan sulfate 2-O-sulfotransferase 1 OS=Homo sapiens OX=9606 GN=HS2ST1 PE=1 SV=1 6.74 1236 - 3.42E+06 - - - -3.0801 - 1.205 0.206 - 97.3 1 2 0 -0.0025 7 0 0 0 1.12E+08 9.97E+07 - - - 1.1526 0.9958 221125_WJC_METTL3_EV_vs_WT_F07.02906.02906.2 0.00145 18-Jul R.GNAESGDSVK.M sp|O95104|SCAF4_HUMAN 1 962.4305 0.27 92616 2906 2 962.426576 482.2225 SR-related and CTD-associated factor 4 OS=Homo sapiens OX=9606 GN=SCAF4 PE=1 SV=3 4.37 1236.5 - 720942 - - - -4.0813 - 1.769 0.345 - 171 1 2 0 -0.0039 10 0 0 0 1.20E+07 4.39E+07 - - - 3.1801 0.9931 221125_WJC_METTL3_EV_vs_WT_F07.02907.02907.2 0.509 14-Jul K.ASNEDVTK[136.11].A sp|O75475|PSIP1_HUMAN 1 870.4174 1.59 92617 2907 2 870.415515 436.216 PC4 and SFRS1-interacting protein OS=Homo sapiens OX=9606 GN=PSIP1 PE=1 SV=1 4.37 1236.6 - 3.60E+06 - - - -2.1955 - 1.517 0.167 - 260.7 1 2 0 -0.0019 8 0 0 0 1.36E+08 8.51E+07 - - - 1.5307 0.9942 221125_WJC_METTL3_EV_vs_WT_F07.02908.02908.2 0.00558 16-Aug R.TQGEGPGPK[136.11].E "sp|Q86UK7|ZN598_HUMAN,tr|H3BQQ2|H3BQQ2_HUMAN,tr|H3BPG6|H3BPG6_HUMAN" 3 877.4385 0.7 92618 2908 2 877.435933 439.7265 E3 ubiquitin-protein ligase ZNF598 OS=Homo sapiens OX=9606 GN=ZNF598 PE=1 SV=1 5.66 1236.6 - 2.90E+06 - - - -2.921 - 1.309 0.309 - 185.2 1 2 0 -0.0026 9 0 0 0 4.09E+07 5.82E+07 - - - 2.1015 0.9373 221125_WJC_METTL3_EV_vs_WT_F07.02912.02912.2 0.145 14-Jul R.VR[166.11]VDSTAK[136.11].V "sp|P78371|TCPB_HUMAN,tr|F8VQ14|F8VQ14_HUMAN,tr|F5GWF6|F5GWF6_HUMAN" 3 892.5097 0.54 92620 2912 2 892.506836 447.2621 T-complex protein 1 subunit beta OS=Homo sapiens OX=9606 GN=CCT2 PE=1 SV=4 8.72 1237.1 - 1.25E+07 - - - -3.21 - 1.559 0.254 - 204.3 1 2 1 -0.0029 8 0 0 0 1.14E+09 2.12E+09 - - - 2.2554 0.9998 221125_WJC_METTL3_EV_vs_WT_F07.02913.02913.2 4.22E-07 14-Oct K.C[160.03]AAC[160.03]QNPR.K sp|P49792|RBP2_HUMAN 1 975.4015 0.69 92621 2913 2 975.399751 488.708 E3 SUMO-protein ligase RanBP2 OS=Homo sapiens OX=9606 GN=RANBP2 PE=1 SV=2 8.07 1237.2 - 854981 - - - -1.7613 - 1.943 0.621 - 541.3 1 2 0 -0.0017 8 0 0 0 4.11E+07 5.95E+07 - - - 5.6305 0.999 221125_WJC_METTL3_EV_vs_WT_F07.02917.02917.2 0.00142 14-Oct K.C[160.03]AAC[160.03]QNPR[166.11].K sp|P49792|RBP2_HUMAN 1 985.4097 0.69 92623 2917 2 985.407093 493.7121 E3 SUMO-protein ligase RanBP2 OS=Homo sapiens OX=9606 GN=RANBP2 PE=1 SV=2 8.07 1237.8 - 1.29E+06 - - - -2.6852 - 1.621 0.425 - 533.2 1 2 0 -0.0026 8 0 0 0 4.13E+07 5.95E+07 - - - 3.6361 0.9978 221125_WJC_METTL3_EV_vs_WT_F07.02918.02918.2 0.515 14-Sep K.SEEANEPK.A sp|Q96T58|MINT_HUMAN 1 902.3981 1.47 92624 2918 2 902.395804 452.2063 Msx2-interacting protein OS=Homo sapiens OX=9606 GN=SPEN PE=1 SV=1 4.25 1237.9 - 488312 - - - -2.5898 - 1.66 0.296 - 438.6 1 2 0 -0.0023 8 0 0 0 4.97E+07 3.38E+07 - - - 2.7551 0.9994 221125_WJC_METTL3_EV_vs_WT_F07.02921.02921.2 0.00535 12-Dec K.K[136.11]LEDGPK[136.11].F "sp|P68104|EF1A1_HUMAN,sp|Q5VTE0|EF1A3_HUMAN,tr|A0A7I2V659|A0A7I2V659_HUMAN,tr|A0A7I2V5N4|A0A7I2V5N4_HUMAN,tr|A0A087WVQ9|A0A087WVQ9_HUMAN,tr|A0A087WV01|A0A087WV01_HUMAN" 6 801.4567 0.41 92625 2921 2 801.454533 401.7356 Elongation factor 1-alpha 1 OS=Homo sapiens OX=9606 GN=EEF1A1 PE=1 SV=1 6.07 1238.3 - 2.23E+07 - - - -2.7275 - 2.179 0.38 - 523.4 1 2 0 -0.0022 7 0 0 0 3.29E+09 7.96E+09 - - - 4.3149 0.8529 221125_WJC_METTL3_EV_vs_WT_F07.02923.02923.2 0.178 14-Sep K.KENLSK[136.11]NK.A sp|Q5T0W9|FA83B_HUMAN 1 967.5542 - 92627 2923 2 967.553966 484.7844 Protein FAM83B OS=Homo sapiens OX=9606 GN=FAM83B PE=1 SV=1 9.7 1238.4 - 1.32E+06 - - - -0.2356 - 1.531 0.02 - 278.5 2 2 1 -0.0002 8 0 0 0 - - - - - 0.3387 0.9528 221125_WJC_METTL3_EV_vs_WT_F07.02926.02926.2 0.101 14-Sep R.VRVDSTAK.V "sp|P78371|TCPB_HUMAN,tr|F8VQ14|F8VQ14_HUMAN,tr|F5GWF6|F5GWF6_HUMAN" 3 874.4872 0.54 92629 2926 2 874.484415 438.2509 T-complex protein 1 subunit beta OS=Homo sapiens OX=9606 GN=CCT2 PE=1 SV=4 8.72 1238.7 - 2.37E+07 - - - -3.2202 - 1.809 0.23 - 330.4 1 2 1 -0.0028 8 0 0 0 1.14E+09 2.12E+09 - - - 2.5267 0.997 221125_WJC_METTL3_EV_vs_WT_F07.02928.02928.2 0.0618 14-Jul K.QEANTEPR[166.11].K sp|Q9UHB9|SRP68_HUMAN 1 953.4442 1 92630 2928 2 953.443679 477.7294 Signal recognition particle subunit SRP68 OS=Homo sapiens OX=9606 GN=SRP68 PE=1 SV=2 4.53 1238.9 - 687307 - - - -0.5391 - 1.273 0.235 - 210 1 2 0 -0.0005 8 0 0 0 8.11E+07 8.12E+07 - - - 1.5045 0.982 221125_WJC_METTL3_EV_vs_WT_F07.02931.02931.2 0.0306 14-Aug R.LR[166.11]PVNQNK[136.11].T "sp|P51114|FXR1_HUMAN,tr|E7EU85|E7EU85_HUMAN,tr|E9PFF5|E9PFF5_HUMAN,tr|C9IZ22|C9IZ22_HUMAN,tr|C9JZE0|C9JZE0_HUMAN,tr|C9JY20|C9JY20_HUMAN,tr|C9J5B4|C9J5B4_HUMAN,tr|C9JAJ4|C9JAJ4_HUMAN,tr|B4DXZ6|B4DXZ6_HUMAN" 9 985.5788 1.54 92632 2931 2 985.575179 493.7967 Fragile X mental retardation syndrome-related protein 1 OS=Homo sapiens OX=9606 GN=FXR1 PE=1 SV=3 11 1239.2 - 2.56E+06 - - - -3.6567 - 1.25 0.257 - 176.3 1 2 0 -0.0036 8 0 0 0 2.48E+08 1.61E+08 - - - 1.6111 0.9946 221125_WJC_METTL3_EV_vs_WT_F07.02940.02940.2 0.00106 16-Sep R.SGGGGYSSR[166.11].R "sp|Q13247|SRSF6_HUMAN,tr|A0A590UK80|A0A590UK80_HUMAN,tr|A0A590UJK4|A0A590UJK4_HUMAN,tr|A0A590UJP7|A0A590UJP7_HUMAN,tr|A0A590UK01|A0A590UK01_HUMAN" 5 836.3652 0.9 92635 2940 2 836.360309 419.1899 Serine\arginine-rich splicing factor 6 OS=Homo sapiens OX=9606 GN=SRSF6 PE=1 SV=2 8.46 1240.4 - 2.43E+06 - - - -5.8659 - 1.867 0.488 - 411.6 1 2 0 -0.0049 9 0 0 0 1.20E+08 1.32E+08 - - - 4.4501 0.9942 221125_WJC_METTL3_EV_vs_WT_F07.02944.02944.2 0.14 14-Aug K.STDEVDSK.R "sp|Q01082|SPTB2_HUMAN,tr|A0A087WUZ3|A0A087WUZ3_HUMAN" 2 879.3822 1.54 92636 2944 2 879.378673 440.6984 "Spectrin beta chain, non-erythrocytic 1 OS=Homo sapiens OX=9606 GN=SPTBN1 PE=1 SV=2" 4.03 1241 - 1.37E+06 - - - -3.9607 - 1.4 0.368 - 157.9 1 2 0 -0.0035 8 0 0 0 1.27E+08 8.20E+07 - - - 2.7727 0.9907 221125_WJC_METTL3_EV_vs_WT_F07.02946.02946.2 0.0691 18-Oct K.TATAGPGTTK[136.11].T sp|P46821|MAP1B_HUMAN 1 911.4804 0.53 92637 2946 2 911.477797 456.7475 Microtubule-associated protein 1B OS=Homo sapiens OX=9606 GN=MAP1B PE=1 SV=2 8.41 1241.2 - 1.07E+06 - - - -2.813 - 1.628 0.169 - 333.4 1 2 0 -0.0026 10 0 0 0 1.47E+07 2.75E+07 - - - 1.6488 0.9948 221125_WJC_METTL3_EV_vs_WT_F07.02949.02949.2 0.00259 16-Aug K.VVC[160.03]DENGSK.G "sp|Q13310|PABP4_HUMAN,sp|Q9H361|PABP3_HUMAN,sp|P11940|PABP1_HUMAN,tr|A0A7I2V5W9|A0A7I2V5W9_HUMAN,tr|A0A7I2YQE4|A0A7I2YQE4_HUMAN,tr|A0A7I2V649|A0A7I2V649_HUMAN,tr|B1ANR0|B1ANR0_HUMAN,tr|A0A7I2V4L7|A0A7I2V4L7_HUMAN,tr|H0YCC8|H0YCC8_HUMAN,tr|H0YAR2|H0YAR2_HUMAN,tr|E7ERJ7|E7ERJ7_HUMAN,tr|A0A7I2V598|A0A7I2V598_HUMAN,tr|A0A7I2YQ88|A0A7I2YQ88_HUMAN,tr|H0YEQ8|H0YEQ8_HUMAN,tr|H0Y5F5|H0Y5F5_HUMAN,tr|H0YBN4|H0YBN4_HUMAN,tr|E5RGH3|E5RGH3_HUMAN,tr|A0A087WTT1|A0A087WTT1_HUMAN,tr|A0A7I2YQ90|A0A7I2YQ90_HUMAN,tr|A0A7I2V4N4|A0A7I2V4N4_HUMAN,tr|E7EQV3|E7EQV3_HUMAN" 21 1006.439 1.31 92638 2949 2 1006.433381 504.2268 Polyadenylate-binding protein 4 OS=Homo sapiens OX=9606 GN=PABPC4 PE=1 SV=1 4.37 1241.6 - 1.24E+06 - - - -5.5433 - 1.523 0.533 - 194.9 1 2 0 -0.0056 9 0 0 0 2.22E+09 1.70E+09 - - - 4.193 0.8767 221125_WJC_METTL3_EV_vs_WT_F07.02953.02953.2 2.06 14-Aug R.SPSRSVSK[136.11].E sp|Q08170|SRSF4_HUMAN 1 854.4701 - 92640 2953 2 854.469096 428.2423 Serine\arginine-rich splicing factor 4 OS=Homo sapiens OX=9606 GN=SRSF4 PE=1 SV=2 11 1242 - 4.87E+06 - - - -1.2101 - 1.407 0.08 - 241.9 1 2 1 -0.001 8 0 0 0 - - - - - 0.6614 0.9977 221125_WJC_METTL3_EV_vs_WT_F07.02954.02954.2 0.0117 12-Jul K.TQLHEER.Q "sp|Q15643|TRIPB_HUMAN,tr|H0YJ97|H0YJ97_HUMAN" 2 911.4461 1.25 92641 2954 2 911.443157 456.7303 Thyroid receptor-interacting protein 11 OS=Homo sapiens OX=9606 GN=TRIP11 PE=1 SV=3 5.37 1242.1 - 2.06E+06 - - - -3.2224 - 1.457 0.395 - 393.8 1 2 0 -0.0029 7 0 0 0 2.05E+08 1.64E+08 - - - 3.1501 0.9978 221125_WJC_METTL3_EV_vs_WT_F07.02955.02955.2 0.0415 12-Jul K.TQLHEER[166.11].Q "sp|Q15643|TRIPB_HUMAN,tr|H0YJ97|H0YJ97_HUMAN" 2 921.4544 1.34 92642 2955 2 921.451332 461.7345 Thyroid receptor-interacting protein 11 OS=Homo sapiens OX=9606 GN=TRIP11 PE=1 SV=3 5.37 1242.2 - 2.34E+06 - - - -3.2905 - 1.622 0.366 - 380.7 1 2 0 -0.003 7 0 0 0 2.19E+08 1.64E+08 - - - 3.2758 0.9828 221125_WJC_METTL3_EV_vs_WT_F07.02959.02959.2 0.00796 16-Jul K.SSAPADSER[166.11].G sp|Q9UKJ3|GPTC8_HUMAN 1 928.4126 1.03 92644 2959 2 928.40692 465.2136 G patch domain-containing protein 8 OS=Homo sapiens OX=9606 GN=GPATCH8 PE=1 SV=2 4.37 1242.6 - 1.23E+06 - - - -6.0738 - 1.418 0.424 - 176.2 1 2 0 -0.0056 9 0 0 0 5.63E+07 5.44E+07 - - - 3.1813 0.9994 221125_WJC_METTL3_EV_vs_WT_F07.02960.02960.2 7.25E-06 16-Aug K.VVC[160.03]DENGSK[136.11].G "sp|Q13310|PABP4_HUMAN,sp|Q9H361|PABP3_HUMAN,sp|P11940|PABP1_HUMAN,tr|A0A7I2V5W9|A0A7I2V5W9_HUMAN,tr|A0A7I2YQE4|A0A7I2YQE4_HUMAN,tr|A0A7I2V649|A0A7I2V649_HUMAN,tr|B1ANR0|B1ANR0_HUMAN,tr|A0A7I2V4L7|A0A7I2V4L7_HUMAN,tr|H0YCC8|H0YCC8_HUMAN,tr|H0YAR2|H0YAR2_HUMAN,tr|E7ERJ7|E7ERJ7_HUMAN,tr|A0A7I2V598|A0A7I2V598_HUMAN,tr|A0A7I2YQ88|A0A7I2YQ88_HUMAN,tr|H0YEQ8|H0YEQ8_HUMAN,tr|H0Y5F5|H0Y5F5_HUMAN,tr|H0YBN4|H0YBN4_HUMAN,tr|E5RGH3|E5RGH3_HUMAN,tr|A0A087WTT1|A0A087WTT1_HUMAN,tr|A0A7I2YQ90|A0A7I2YQ90_HUMAN,tr|A0A7I2V4N4|A0A7I2V4N4_HUMAN,tr|E7EQV3|E7EQV3_HUMAN" 21 1014.4532 1.31 92645 2960 2 1014.450141 508.2339 Polyadenylate-binding protein 4 OS=Homo sapiens OX=9606 GN=PABPC4 PE=1 SV=1 4.37 1242.7 - 5.30E+06 - - - -2.976 - 1.669 0.544 - 170.3 1 2 0 -0.003 9 0 0 0 2.22E+09 1.70E+09 - - - 4.5399 0.9984 221125_WJC_METTL3_EV_vs_WT_F07.02965.02965.2 0.00872 12-Aug K.KLEDGPK.F "sp|P68104|EF1A1_HUMAN,sp|Q5VTE0|EF1A3_HUMAN,tr|A0A7I2V659|A0A7I2V659_HUMAN,tr|A0A7I2V5N4|A0A7I2V5N4_HUMAN,tr|A0A087WVQ9|A0A087WVQ9_HUMAN,tr|A0A087WV01|A0A087WV01_HUMAN" 6 785.4283 0.41 92647 2965 2 785.426261 393.7214 Elongation factor 1-alpha 1 OS=Homo sapiens OX=9606 GN=EEF1A1 PE=1 SV=1 6.07 1243.3 - 5.98E+07 - - - -2.6202 - 1.605 0.347 - 247.4 1 2 0 -0.0021 7 0 0 0 3.29E+09 7.96E+09 - - - 3.1024 0.9437 221125_WJC_METTL3_EV_vs_WT_F07.02972.02972.2 1.03 14-Jun K.TVDGPSGK.L "sp|P04406|G3P_HUMAN,tr|E7EUT5|E7EUT5_HUMAN" 2 759.3763 0.7 92648 2972 2 759.374474 380.6954 Glyceraldehyde-3-phosphate dehydrogenase OS=Homo sapiens OX=9606 GN=GAPDH PE=1 SV=3 5.5 1244.4 - 4.75E+06 - - - -2.3822 - 1.04 0.151 - 86.7 2 2 0 -0.0018 8 0 0 0 3.07E+08 4.37E+08 - - - 0.1395 0.9994 221125_WJC_METTL3_EV_vs_WT_F07.02973.02973.2 0.0286 16-Sep K.LASTSC[160.03]GQK[136.11].S "sp|O75410|TACC1_HUMAN,tr|E7EVI4|E7EVI4_HUMAN,tr|E5RFM9|E5RFM9_HUMAN,tr|A0A0C4DGD5|A0A0C4DGD5_HUMAN,tr|R4GMT7|R4GMT7_HUMAN,tr|H0YAY0|H0YAY0_HUMAN,tr|A0A0C4DGD3|A0A0C4DGD3_HUMAN,tr|H0YBT8|H0YBT8_HUMAN,tr|E7ET87|E7ET87_HUMAN" 9 958.4633 0.96 92649 2973 2 958.462708 480.2389 Transforming acidic coiled-coil-containing protein 1 OS=Homo sapiens OX=9606 GN=TACC1 PE=1 SV=2 8.22 1244.5 - 1.69E+06 - - - -0.65 - 1.728 0.301 - 227.3 1 2 0 -0.0006 9 0 0 0 1.87E+08 1.95E+08 - - - 2.8464 0.9983 221125_WJC_METTL3_EV_vs_WT_F07.02978.02978.2 0.0248 16-Sep K.LASTSC[160.03]GQK.S "sp|O75410|TACC1_HUMAN,tr|E7EVI4|E7EVI4_HUMAN,tr|E5RFM9|E5RFM9_HUMAN,tr|A0A0C4DGD5|A0A0C4DGD5_HUMAN,tr|R4GMT7|R4GMT7_HUMAN,tr|H0YAY0|H0YAY0_HUMAN,tr|A0A0C4DGD3|A0A0C4DGD3_HUMAN,tr|H0YBT8|H0YBT8_HUMAN,tr|E7ET87|E7ET87_HUMAN" 9 950.4491 0.9 92652 2978 2 950.446845 476.2318 Transforming acidic coiled-coil-containing protein 1 OS=Homo sapiens OX=9606 GN=TACC1 PE=1 SV=2 8.22 1245 - 2.78E+06 - - - -2.4052 - 1.595 0.333 - 229 1 2 0 -0.0023 9 0 0 0 1.87E+08 2.09E+08 - - - 2.8505 0.9952 221125_WJC_METTL3_EV_vs_WT_F07.02981.02981.2 0.00144 16-Sep K.GPC[160.03]SPSSSR.V "sp|Q15517|CDSN_HUMAN,tr|G8JLG2|G8JLG2_HUMAN,tr|Q2L6G8|Q2L6G8_HUMAN" 3 933.3974 10.85 92655 2981 2 933.39422 467.706 Corneodesmosin OS=Homo sapiens OX=9606 GN=CDSN PE=1 SV=3 8.25 1245.3 - 778453 - - - -3.438 - 1.597 0.299 - 351.7 1 2 0 -0.0032 9 0 0 0 6.19E+08 5.71E+07 - - - 2.6027 0.9889 221125_WJC_METTL3_EV_vs_WT_F07.02985.02985.2 1.38 14-Sep K.KGPAAIQK.N sp|P35527|K1C9_HUMAN 1 811.4916 63931.51 92658 2985 2 811.488496 406.7531 "Keratin, type I cytoskeletal 9 OS=Homo sapiens OX=9606 GN=KRT9 PE=1 SV=3" 10 1245.8 - 1.91E+07 - - - -3.8103 - 1.685 0.2 - 240.7 1 2 0 -0.0031 8 0 0 0 7.85E+09 1.23E+05 - - - 2.0909 0.9991 221125_WJC_METTL3_EV_vs_WT_F07.02987.02987.2 0.0232 16-Jul K.AAESETPGK[136.11].S "sp|O76021|RL1D1_HUMAN,tr|J3QSV6|J3QSV6_HUMAN" 2 896.4331 3.23 92659 2987 2 896.43246 449.2238 Ribosomal L1 domain-containing protein 1 OS=Homo sapiens OX=9606 GN=RSL1D1 PE=1 SV=3 4.53 1246 - 1.09E+06 - - - -0.6872 - 1.643 0.277 - 208.1 1 2 0 -0.0006 9 0 0 0 1.31E+08 4.06E+07 - - - 2.5232 0.9773 221125_WJC_METTL3_EV_vs_WT_F07.02989.02989.2 0.031 16-Jun R.QQGPGTGTR.D sp|Q9Y6J9|TAF6L_HUMAN 1 900.4413 0.44 92660 2989 2 900.438668 451.2279 TAF6-like RNA polymerase II p300\CBP-associated factor-associated factor 65 kDa subunit 6L OS=Homo sapiens OX=9606 GN=TAF6L PE=1 SV=1 9.75 1246.2 - 848006 - - - -2.9708 - 1.448 0.129 - 174.9 1 2 0 -0.0027 9 0 0 0 8.94E+07 2.04E+08 - - - 1.0639 0.9797 221125_WJC_METTL3_EV_vs_WT_F07.02996.02996.2 0.199 12-Jul K.KLEDGPK[136.11].F "sp|P68104|EF1A1_HUMAN,sp|Q5VTE0|EF1A3_HUMAN,tr|A0A7I2V659|A0A7I2V659_HUMAN,tr|A0A7I2V5N4|A0A7I2V5N4_HUMAN,tr|A0A087WVQ9|A0A087WVQ9_HUMAN,tr|A0A087WV01|A0A087WV01_HUMAN" 6 793.4425 - 92664 2996 2 793.440456 397.7285 Elongation factor 1-alpha 1 OS=Homo sapiens OX=9606 GN=EEF1A1 PE=1 SV=1 6.07 1246.9 - 4.29E+06 - - - -2.6001 - 1.256 0.161 - 167.2 1 2 0 -0.0021 7 0 0 0 - - - - - 0.9517 0.9652 221125_WJC_METTL3_EV_vs_WT_F07.02998.02998.2 2.6 12-Jun R.TQSIQGK.G sp|Q53HL2|BOREA_HUMAN 1 760.4079 1.16 92665 2998 2 760.405933 381.2112 Borealin OS=Homo sapiens OX=9606 GN=CDCA8 PE=1 SV=2 8.41 1247.1 - 6.78E+06 - - - -2.6104 - 1.005 0.206 - 113.6 1 2 0 -0.002 7 0 0 0 1.84E+08 1.59E+08 - - - 0.5777 0.9944 221125_WJC_METTL3_EV_vs_WT_F07.03002.03002.2 0.0278 18-Aug R.AEATAASTSR.S sp|O95721|SNP29_HUMAN 1 963.4621 2.13 92667 3002 2 963.459411 482.7383 Synaptosomal-associated protein 29 OS=Homo sapiens OX=9606 GN=SNAP29 PE=1 SV=1 6.05 1247.5 - 2.72E+06 - - - -2.8304 - 1.734 0.202 - 298.5 1 2 0 -0.0027 10 0 0 0 6.87E+07 3.22E+07 - - - 2.0685 0.8507 221125_WJC_METTL3_EV_vs_WT_F07.03009.03009.2 1.13 16-May K.SSAPADSER.G sp|Q9UKJ3|GPTC8_HUMAN 1 918.4043 0.23 92671 3009 2 918.401336 460.2094 G patch domain-containing protein 8 OS=Homo sapiens OX=9606 GN=GPATCH8 PE=1 SV=2 4.37 1248.3 - 1.24E+06 - - - -3.2154 - 1.272 0.051 - 96 4 2 0 -0.003 9 0 0 0 6.21E+07 2.69E+08 - - - -0.1561 0.8911 221125_WJC_METTL3_EV_vs_WT_F07.03010.03010.2 7.11 14-Jun K.IVEEETKK.E sp|P55081|MFAP1_HUMAN 1 974.5284 1.08 92672 3010 2 974.527604 488.2715 Microfibrillar-associated protein 1 OS=Homo sapiens OX=9606 GN=MFAP1 PE=1 SV=2 4.79 1248.3 - 1.66E+06 - - - -0.8445 - 1.055 0.031 - 78.8 5 2 0 -0.0008 8 0 0 0 6.34E+07 5.88E+07 - - - -0.881 0.9908 221125_WJC_METTL3_EV_vs_WT_F07.03018.03018.2 0.154 14-Aug K.ISEQSDAK.L sp|P25705|ATPA_HUMAN 1 876.4189 1.47 92676 3018 2 876.421918 439.2167 "ATP synthase subunit alpha, mitochondrial OS=Homo sapiens OX=9606 GN=ATP5F1A PE=1 SV=1" 4.37 1249.2 - 2.24E+06 - - - 3.4709 - 1.522 0.237 - 161.5 1 2 0 0.003 8 0 0 0 1.67E+08 1.14E+08 - - - 2.0573 0.998 221125_WJC_METTL3_EV_vs_WT_F07.03019.03019.2 0.0114 14-Aug K.ISEQSDAK[136.11].L sp|P25705|ATPA_HUMAN 1 884.4331 1.49 92677 3019 2 884.430943 443.2238 "ATP synthase subunit alpha, mitochondrial OS=Homo sapiens OX=9606 GN=ATP5F1A PE=1 SV=1" 4.37 1249.3 - 1.78E+06 - - - -2.4117 - 1.71 0.276 - 158.9 1 2 0 -0.0021 8 0 0 0 1.66E+08 1.11E+08 - - - 2.6969 0.9827 221125_WJC_METTL3_EV_vs_WT_F07.03022.03022.2 0.417 14-Jul R.EVLHGNQR.K sp|P62906|RL10A_HUMAN 1 951.4886 1.03 92678 3022 2 951.486438 476.7516 60S ribosomal protein L10a OS=Homo sapiens OX=9606 GN=RPL10A PE=1 SV=2 6.85 1249.7 - 1.05E+07 - - - -2.3006 - 1.201 0.179 - 207.6 1 2 0 -0.0022 8 0 0 0 6.79E+08 6.60E+08 - - - 0.9148 0.9903 221125_WJC_METTL3_EV_vs_WT_F07.03023.03023.2 0.00953 14-Sep R.K[136.11]LTPQGQR[166.11].D "sp|P39019|RS19_HUMAN,tr|A0A075B6E2|A0A075B6E2_HUMAN" 2 944.5522 1.11 92679 3023 2 944.549317 473.2834 40S ribosomal protein S19 OS=Homo sapiens OX=9606 GN=RPS19 PE=1 SV=2 11 1249.8 - 2.36E+06 - - - -3.0882 - 1.997 0.088 - 389.4 1 2 0 -0.0029 8 0 0 0 1.49E+08 1.34E+08 - - - 1.776 0.9947 221125_WJC_METTL3_EV_vs_WT_F07.03028.03028.2 0.162 14-Aug R.KLTPQGQR.D "sp|P39019|RS19_HUMAN,tr|A0A075B6E2|A0A075B6E2_HUMAN" 2 926.5298 1.11 92682 3028 2 926.526857 464.2722 40S ribosomal protein S19 OS=Homo sapiens OX=9606 GN=RPS19 PE=1 SV=2 11 1250.2 - 2.76E+06 - - - -3.1375 - 1.717 0.221 - 293.4 1 2 0 -0.0029 8 0 0 0 1.49E+08 1.34E+08 - - - 2.3028 0.9988 221125_WJC_METTL3_EV_vs_WT_F07.03038.03038.2 0.00256 12-Aug R.THVGSYK.G "sp|Q12849|GRSF1_HUMAN,tr|H0YAK1|H0YAK1_HUMAN,tr|H0Y8R1|H0Y8R1_HUMAN,tr|F5H5I6|F5H5I6_HUMAN" 4 790.3974 1.73 92686 3038 2 790.39549 396.206 G-rich sequence factor 1 OS=Homo sapiens OX=9606 GN=GRSF1 PE=1 SV=3 8.29 1251.6 - 3.63E+06 - - - -2.357 - 1.599 0.358 - 356.5 1 2 0 -0.0019 7 0 0 0 1.19E+08 6.90E+07 - - - 3.1719 0.9955 221125_WJC_METTL3_EV_vs_WT_F07.03042.03042.2 0.00705 12-Jul K.FAEEDK[136.11]K[136.11].L "sp|P11021|BIP_HUMAN,tr|A0A7P0TB36|A0A7P0TB36_HUMAN,tr|A0A7P0TAI0|A0A7P0TAI0_HUMAN" 3 881.4465 0.83 92689 3042 2 881.443477 441.7306 Endoplasmic reticulum chaperone BiP OS=Homo sapiens OX=9606 GN=HSPA5 PE=1 SV=2 4.68 1252 - 7.69E+06 - - - -3.484 - 1.503 0.319 - 140.2 1 2 0 -0.0031 7 0 0 0 4.00E+08 4.80E+08 - - - 2.6872 0.9984 221125_WJC_METTL3_EV_vs_WT_F07.03047.03047.2 0.0111 16-Aug R.QVAQSEAEK[136.11].K "sp|Q8WU90|ZC3HF_HUMAN,tr|F8WB26|F8WB26_HUMAN" 2 996.4967 0.55 92692 3047 2 996.494934 499.2556 Zinc finger CCCH domain-containing protein 15 OS=Homo sapiens OX=9606 GN=ZC3H15 PE=1 SV=1 4.53 1252.5 - 1.10E+06 - - - -1.8113 - 1.544 0.304 - 136 1 2 0 -0.0018 9 0 0 0 2.17E+07 3.99E+07 - - - 2.5425 0.9986 221125_WJC_METTL3_EV_vs_WT_F07.03055.03055.2 0.00294 14-Sep R.TEVEENQK[136.11].Y sp|Q9NYU2|UGGG1_HUMAN 1 983.4651 0.04 92697 3055 2 983.462438 492.7398 UDP-glucose:glycoprotein glucosyltransferase 1 OS=Homo sapiens OX=9606 GN=UGGT1 PE=1 SV=3 4.25 1253.2 - 4.55E+06 - - - -2.7118 - 1.588 0.387 - 359.7 1 2 0 -0.0027 8 0 0 0 5.96E+06 1.45E+08 - - - 3.2933 0.9996 221125_WJC_METTL3_EV_vs_WT_F07.03062.03062.2 4.27E-06 18-Nov K.TASDQATTAR.L "sp|O60573|IF4E2_HUMAN,tr|B4E1E4|B4E1E4_HUMAN,tr|B9A044|B9A044_HUMAN,tr|B8ZZL3|B8ZZL3_HUMAN,tr|B9A023|B9A023_HUMAN,tr|B8ZZ50|B8ZZ50_HUMAN,tr|C9JEL3|C9JEL3_HUMAN" 7 1020.4836 1.07 92702 3062 2 1020.480507 511.2491 Eukaryotic translation initiation factor 4E type 2 OS=Homo sapiens OX=9606 GN=EIF4E2 PE=1 SV=1 5.5 1253.8 - 3.19E+06 - - - -3.0329 - 2.235 0.553 - 459.2 1 2 0 -0.0031 10 0 0 0 4.05E+08 3.78E+08 - - - 5.3694 0.9668 221125_WJC_METTL3_EV_vs_WT_F07.03067.03067.2 2.49 12-Aug R.KVTVSAR.T sp|Q9BPX3|CND3_HUMAN 1 759.4603 0.61 92705 3067 2 759.458359 380.7374 Condensin complex subunit 3 OS=Homo sapiens OX=9606 GN=NCAPG PE=1 SV=1 11 1254.3 - 2.03E+06 - - - -2.5386 - 1.228 0.12 - 276.9 1 2 0 -0.0019 7 0 0 0 2.59E+07 4.25E+07 - - - 0.5775 0.9907 221125_WJC_METTL3_EV_vs_WT_F07.03078.03078.2 0.106 16-Sep R.QVAQSEAEK.K "sp|Q8WU90|ZC3HF_HUMAN,tr|F8WB26|F8WB26_HUMAN" 2 988.4825 0.55 92711 3078 2 988.479083 495.2485 Zinc finger CCCH domain-containing protein 15 OS=Homo sapiens OX=9606 GN=ZC3H15 PE=1 SV=1 4.53 1255.6 - 816461 - - - -3.4963 - 1.324 0.297 - 210 1 2 0 -0.0035 9 0 0 0 2.17E+07 3.99E+07 - - - 2.0455 0.9724 221125_WJC_METTL3_EV_vs_WT_F07.03083.03083.2 0.000111 18-Sep Q.SVGGDSSADR[166.11].L "sp|Q86U44|MTA70_HUMAN,tr|H0YFV6|H0YFV6_HUMAN" 2 959.4184 0.03 92713 3083 2 959.416199 480.7165 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 4.21 1256.2 - 1.36E+07 - - - -2.2649 - 1.624 0.518 - 162.6 1 1 0 -0.0022 10 0 0 0 2.94E+08 1.10E+10 - - - 4.2197 0.9998 221125_WJC_METTL3_EV_vs_WT_F07.03085.03085.2 4.50E-05 18-Nov R.VEHAVAEGAK.N "sp|Q16512|PKN1_HUMAN,tr|K7EM57|K7EM57_HUMAN" 2 1009.5193 2.55 92715 3085 2 1009.519837 505.7669 Serine\threonine-protein kinase N1 OS=Homo sapiens OX=9606 GN=PKN1 PE=1 SV=2 5.4 1256.4 - 1.77E+06 - - - 0.5725 - 2.061 0.488 - 529.1 1 2 0 0.0006 10 0 0 0 5.07E+07 1.99E+07 - - - 4.6638 0.9996 221125_WJC_METTL3_EV_vs_WT_F07.03089.03089.2 3.90E-07 13/18 K.TASDQATTAR[166.11].L "sp|O60573|IF4E2_HUMAN,tr|B4E1E4|B4E1E4_HUMAN,tr|B9A044|B9A044_HUMAN,tr|B8ZZL3|B8ZZL3_HUMAN,tr|B9A023|B9A023_HUMAN,tr|B8ZZ50|B8ZZ50_HUMAN,tr|C9JEL3|C9JEL3_HUMAN" 7 1030.4919 1.07 92717 3089 2 1030.489216 516.2532 Eukaryotic translation initiation factor 4E type 2 OS=Homo sapiens OX=9606 GN=EIF4E2 PE=1 SV=1 5.5 1256.9 - 1.05E+07 - - - -2.5774 - 2.277 0.506 - 578.6 1 2 0 -0.0027 10 0 0 0 4.05E+08 3.78E+08 - - - 5.0743 0.9713 221125_WJC_METTL3_EV_vs_WT_F07.03100.03100.2 1.4 12-Jul K.SSQEEVR[166.11].S sp|P52597|HNRPF_HUMAN 1 843.3962 0.96 92723 3100 2 843.392657 422.7054 Heterogeneous nuclear ribonucleoprotein F OS=Homo sapiens OX=9606 GN=HNRNPF PE=1 SV=3 4.53 1258.1 - 6.50E+06 - - - -4.1772 - 1.5 0.164 - 390.1 1 2 0 -0.0035 7 0 0 0 1.32E+08 1.38E+08 - - - 1.5359 0.9975 221125_WJC_METTL3_EV_vs_WT_F07.03108.03108.2 0.00544 14-Jun K.ANVEKPVK.L "sp|Q9BQQ3|GORS1_HUMAN,sp|Q9H8Y8|GORS2_HUMAN,tr|G3V0G1|G3V0G1_HUMAN,tr|C9J9V9|C9J9V9_HUMAN,tr|C9J0V5|C9J0V5_HUMAN,tr|H7C0J2|H7C0J2_HUMAN" 6 883.5127 1.49 92728 3108 2 883.510565 442.7636 Golgi reassembly-stacking protein 1 OS=Homo sapiens OX=9606 GN=GORASP1 PE=1 SV=3 8.64 1258.8 - 2.51E+06 - - - -2.4357 - 1.385 0.34 - 194.5 1 2 0 -0.0022 8 0 0 0 8.70E+07 5.83E+07 - - - 2.5339 0.9926 221125_WJC_METTL3_EV_vs_WT_F07.03109.03109.2 0.0532 14-Jul K.EAETPQAK[136.11].K "sp|Q14978|NOLC1_HUMAN,tr|A0A0A0MRM9|A0A0A0MRM9_HUMAN" 2 880.4382 0.66 92729 3109 2 880.435607 441.2264 Nucleolar and coiled-body phosphoprotein 1 OS=Homo sapiens OX=9606 GN=NOLC1 PE=1 SV=2 4.53 1258.9 - 1.70E+06 - - - -2.902 - 1.262 0.29 - 233.1 1 2 0 -0.0026 8 0 0 0 1.76E+08 2.67E+08 - - - 1.8839 0.9966 221125_WJC_METTL3_EV_vs_WT_F07.03121.03121.2 0.0272 16-Aug K.SVQATTENK[136.11].E sp|Q13011|ECH1_HUMAN 1 984.4967 2.3 92733 3121 2 984.493964 493.2556 "Delta(3,5)-Delta(2,4)-dienoyl-CoA isomerase, mitochondrial OS=Homo sapiens OX=9606 GN=ECH1 PE=1 SV=2" 5.72 1260.4 - 1.21E+06 - - - -2.8187 - 1.562 0.293 - 131.9 1 2 0 -0.0028 9 0 0 0 1.71E+08 7.43E+07 - - - 2.4944 0.9982 221125_WJC_METTL3_EV_vs_WT_F07.03125.03125.2 0.000917 16-Sep K.SVQATTENK.E sp|Q13011|ECH1_HUMAN 1 976.4825 2.32 92735 3125 2 976.478611 489.2485 "Delta(3,5)-Delta(2,4)-dienoyl-CoA isomerase, mitochondrial OS=Homo sapiens OX=9606 GN=ECH1 PE=1 SV=2" 5.72 1260.9 - 4.72E+06 - - - -4.0226 - 1.81 0.455 - 225 1 2 0 -0.0039 9 0 0 0 1.73E+08 7.46E+07 - - - 4.1169 0.9844 221125_WJC_METTL3_EV_vs_WT_F07.03130.03130.2 0.387 14-Aug K.SNLNTSGK.T "sp|Q9NZN8|CNOT2_HUMAN,tr|F8VRS8|F8VRS8_HUMAN,tr|F8VUB4|F8VUB4_HUMAN,tr|H0YH84|H0YH84_HUMAN,tr|F8VV52|F8VV52_HUMAN,tr|F8W145|F8W145_HUMAN" 6 819.4086 0.83 92737 3130 2 819.405229 410.7116 CCR4-NOT transcription complex subunit 2 OS=Homo sapiens OX=9606 GN=CNOT2 PE=1 SV=1 8.47 1261.4 - 3.91E+06 - - - -4.1701 - 1.608 0.21 - 383 1 2 0 -0.0034 8 0 0 0 7.91E+07 9.55E+07 - - - 2.0235 0.9913 221125_WJC_METTL3_EV_vs_WT_F07.03137.03137.2 0.123 16-Oct K.AQAVEQQAK.K "sp|Q12830|BPTF_HUMAN,tr|F5GXF5|F5GXF5_HUMAN,tr|E9PE19|E9PE19_HUMAN,tr|J3QQK4|J3QQK4_HUMAN,tr|E7ETD6|E7ETD6_HUMAN,tr|A0A2R8Y7Q1|A0A2R8Y7Q1_HUMAN" 6 971.5036 1.01 92742 3137 2 971.50005 486.7591 Nucleosome-remodeling factor subunit BPTF OS=Homo sapiens OX=9606 GN=BPTF PE=1 SV=3 6.05 1262.3 - 1.03E+06 - - - -3.6634 - 1.855 0.187 - 480.2 1 2 0 -0.0036 9 0 0 0 1.73E+07 1.72E+07 - - - 2.2086 0.804 221125_WJC_METTL3_EV_vs_WT_F07.03141.03141.2 0.0958 16-Jun H.QPASSGDDR[166.11].A "sp|Q9NR09|BIRC6_HUMAN,tr|A0A3B3IUB9|A0A3B3IUB9_HUMAN" 2 941.4078 0.84 92744 3141 2 941.408167 471.7112 Baculoviral IAP repeat-containing protein 6 OS=Homo sapiens OX=9606 GN=BIRC6 PE=1 SV=2 4.21 1262.7 - 2.43E+06 - - - 0.3813 - 1.043 0.289 - 156.4 1 1 0 0.0004 9 0 0 0 9.89E+07 1.18E+08 - - - 1.2972 0.9961 221125_WJC_METTL3_EV_vs_WT_F07.03142.03142.2 0.0425 12-Aug R.HEQVVER[166.11].L "sp|Q8NBT2|SPC24_HUMAN,tr|K7ERQ7|K7ERQ7_HUMAN,tr|K7EJH0|K7EJH0_HUMAN,tr|K7EMX1|K7EMX1_HUMAN,tr|K7EJV2|K7EJV2_HUMAN,tr|A0A0A0MSN0|A0A0A0MSN0_HUMAN,tr|K7ESQ2|K7ESQ2_HUMAN" 7 905.4594 2.3 92745 3142 2 905.456667 453.737 Kinetochore protein Spc24 OS=Homo sapiens OX=9606 GN=SPC24 PE=1 SV=2 5.4 1262.8 - 3.42E+06 - - - -3.0725 - 1.6 0.271 - 220.6 1 2 0 -0.0028 7 0 0 0 6.38E+08 2.77E+08 - - - 2.531 0.9996 221125_WJC_METTL3_EV_vs_WT_F07.03143.03143.2 0.000208 18-Nov K.MASATSSSQR.D "sp|Q96T88|UHRF1_HUMAN,tr|A0A087WWG9|A0A087WWG9_HUMAN,tr|A0A087WTW0|A0A087WTW0_HUMAN,tr|A0A087WVR3|A0A087WVR3_HUMAN" 4 1024.4608 1.21 92746 3143 2 1024.458131 513.2377 E3 ubiquitin-protein ligase UHRF1 OS=Homo sapiens OX=9606 GN=UHRF1 PE=1 SV=1 9.5 1262.9 - 1.62E+06 - - - -2.5643 - 2.175 0.514 - 523.5 1 2 0 -0.0026 10 0 0 0 2.24E+07 1.86E+07 - - - 5.0055 0.9968 221125_WJC_METTL3_EV_vs_WT_F07.03148.03148.2 0.0365 12-Jul R.QQENMQR.Q "sp|O15372|EIF3H_HUMAN,tr|B3KS98|B3KS98_HUMAN,tr|A0A087WZK9|A0A087WZK9_HUMAN" 3 932.4134 1.75 92749 3148 2 932.410698 467.214 Eukaryotic translation initiation factor 3 subunit H OS=Homo sapiens OX=9606 GN=EIF3H PE=1 SV=1 6 1263.4 - 3.62E+06 - - - -2.9129 - 1.52 0.304 - 347.6 1 2 0 -0.0027 7 0 0 0 2.58E+08 1.48E+08 - - - 2.6122 0.9859 221125_WJC_METTL3_EV_vs_WT_F07.03149.03149.2 0.00172 12-Aug R.C[160.03]QAQVSR[166.11].R "sp|Q03393|PTPS_HUMAN,tr|E9PKY8|E9PKY8_HUMAN,tr|E9PJM0|E9PJM0_HUMAN" 3 857.4053 3.9 92750 3149 2 857.402042 429.7099 6-pyruvoyl tetrahydrobiopterin synthase OS=Homo sapiens OX=9606 GN=PTS PE=1 SV=1 8.25 1263.4 - 1.99E+06 - - - -3.8068 - 1.553 0.197 - 312.5 1 2 0 -0.0033 7 0 0 0 4.58E+08 1.17E+08 - - - 1.8898 0.9964 221125_WJC_METTL3_EV_vs_WT_F07.03150.03150.2 0.0252 14-Aug R.GVSTC[160.03]STR.F "sp|P13646|K1C13_HUMAN,tr|K7EMJ2|K7EMJ2_HUMAN,tr|K7ERE3|K7ERE3_HUMAN,tr|K7EQH6|K7EQH6_HUMAN" 4 866.3916 2.8 92751 3150 2 866.388009 434.2031 "Keratin, type I cytoskeletal 13 OS=Homo sapiens OX=9606 GN=KRT13 PE=1 SV=4" 8.25 1263.5 - 888051 - - - -4.1632 - 1.852 0.341 - 172.3 1 2 0 -0.0036 8 0 0 0 8.95E+06 3.20E+06 - - - 3.4171 0.9985 221125_WJC_METTL3_EV_vs_WT_F07.03156.03156.2 0.00972 14-Aug K.SC[160.03]QVENGR.V "sp|Q9NR56|MBNL1_HUMAN,sp|Q5VZF2|MBNL2_HUMAN,tr|H7C4T5|H7C4T5_HUMAN,tr|A0A0A0MQX8|A0A0A0MQX8_HUMAN,tr|A0A7P0T9I3|A0A7P0T9I3_HUMAN,tr|C9JP00|C9JP00_HUMAN,tr|O95205|O95205_HUMAN" 7 948.4083 0.04 92754 3156 2 948.4055 475.2114 Muscleblind-like protein 1 OS=Homo sapiens OX=9606 GN=MBNL1 PE=1 SV=2 5.72 1264.3 - 3.60E+06 - - - -2.9829 - 1.502 0.424 - 317.2 1 2 0 -0.0028 8 0 0 0 2.66E+08 7.22E+09 - - - 3.3987 0.9936 221125_WJC_METTL3_EV_vs_WT_F07.03162.03162.2 0.016 12-Aug R.NGEMIKK.L "sp|Q96I24|FUBP3_HUMAN,sp|Q96AE4|FUBP1_HUMAN,tr|E9PEB5|E9PEB5_HUMAN" 3 818.432 3.31 92757 3162 2 818.429762 410.2233 Far upstream element-binding protein 3 OS=Homo sapiens OX=9606 GN=FUBP3 PE=1 SV=2 8.59 1264.9 - 3.95E+06 - - - -2.7638 - 1.529 0.207 - 326.7 1 2 0 -0.0023 7 0 0 0 8.72E+08 2.63E+08 - - - 1.9146 0.9993 221125_WJC_METTL3_EV_vs_WT_F07.03177.03177.2 0.000762 14-Sep K.SC[160.03]QVENGR[166.11].V "sp|Q9NR56|MBNL1_HUMAN,sp|Q5VZF2|MBNL2_HUMAN,tr|H7C4T5|H7C4T5_HUMAN,tr|A0A0A0MQX8|A0A0A0MQX8_HUMAN,tr|A0A7P0T9I3|A0A7P0T9I3_HUMAN,tr|C9JP00|C9JP00_HUMAN,tr|O95205|O95205_HUMAN" 7 958.4166 0.04 92764 3177 2 958.41418 480.2156 Muscleblind-like protein 1 OS=Homo sapiens OX=9606 GN=MBNL1 PE=1 SV=2 5.72 1266.9 - 3.52E+06 - - - -2.524 - 1.667 0.448 - 353.9 1 2 0 -0.0024 8 0 0 0 2.52E+08 7.19E+09 - - - 3.8904 0.9979 221125_WJC_METTL3_EV_vs_WT_F07.03178.03178.2 0.166 14-Jul K.IENHEGVR.R "sp|P14618|KPYM_HUMAN,tr|H3BQ34|H3BQ34_HUMAN,tr|B4DNK4|B4DNK4_HUMAN,tr|A0A804F6T5|A0A804F6T5_HUMAN,tr|H3BTN5|H3BTN5_HUMAN,tr|H3BR70|H3BR70_HUMAN,tr|A0A804F729|A0A804F729_HUMAN" 7 952.4726 0.67 92765 3178 2 952.471752 477.2436 Pyruvate kinase PKM OS=Homo sapiens OX=9606 GN=PKM PE=1 SV=4 5.4 1266.9 - 2.75E+06 - - - -0.9355 - 1.519 0.211 - 202.3 1 2 0 -0.0009 8 0 0 0 9.06E+07 1.34E+08 - - - 1.86 0.9933 221125_WJC_METTL3_EV_vs_WT_F07.03179.03179.2 0.116 16-Jun R.KGGPAPVDR[166.11].K "sp|O75081|MTG16_HUMAN,tr|H3BNI7|H3BNI7_HUMAN" 2 905.4958 - 92766 3179 2 905.494501 453.7552 Protein CBFA2T3 OS=Homo sapiens OX=9606 GN=CBFA2T3 PE=1 SV=2 8.75 1267 - 1.20E+07 - - - -1.4732 - 1.225 0.212 - 105.8 1 2 0 -0.0013 9 0 0 0 - - - - - 1.1935 0.9729 221125_WJC_METTL3_EV_vs_WT_F07.03181.03181.2 0.0337 14-Jul K.EAETPQAK.K "sp|Q14978|NOLC1_HUMAN,tr|A0A0A0MRM9|A0A0A0MRM9_HUMAN" 2 872.424 0.97 92768 3181 2 872.420782 437.2193 Nucleolar and coiled-body phosphoprotein 1 OS=Homo sapiens OX=9606 GN=NOLC1 PE=1 SV=2 4.53 1267.1 - 1.62E+06 - - - -3.645 - 1.209 0.227 - 159.7 1 2 0 -0.0032 8 0 0 0 3.01E+08 3.10E+08 - - - 1.289 0.9894 221125_WJC_METTL3_EV_vs_WT_F07.03186.03186.2 2.96 12-Aug R.QRPAEIK.D sp|P02533|K1C14_HUMAN 1 840.4818 810.52 92771 3186 2 840.479459 421.2482 "Keratin, type I cytoskeletal 14 OS=Homo sapiens OX=9606 GN=KRT14 PE=1 SV=4" 8.75 1267.7 - 8.80E+06 - - - -2.727 - 1.465 0.169 - 345.8 1 2 0 -0.0023 7 0 0 0 4.98E+09 6.14E+06 - - - 1.4984 0.8597 221125_WJC_METTL3_EV_vs_WT_F07.03187.03187.2 0.724 12-May R.SGEMIK[136.11]K[136.11].L "sp|Q92945|FUBP2_HUMAN,tr|M0R0I5|M0R0I5_HUMAN,tr|M0R0C6|M0R0C6_HUMAN,tr|A0A087WTP3|A0A087WTP3_HUMAN" 4 807.4495 1.1 92772 3187 2 807.447745 404.732 Far upstream element-binding protein 2 OS=Homo sapiens OX=9606 GN=KHSRP PE=1 SV=4 8.31 1267.8 - 3.05E+06 - - - -2.2045 - 1.074 0.022 - 123.5 1 2 0 -0.0018 7 0 0 0 6.01E+07 5.45E+07 - - - -0.5709 0.9965 221125_WJC_METTL3_EV_vs_WT_F07.03192.03192.2 0.0728 12-Oct R.HEQVVER.L "sp|Q8NBT2|SPC24_HUMAN,tr|K7ERQ7|K7ERQ7_HUMAN,tr|K7EJH0|K7EJH0_HUMAN,tr|K7EMX1|K7EMX1_HUMAN,tr|K7EJV2|K7EJV2_HUMAN,tr|A0A0A0MSN0|A0A0A0MSN0_HUMAN,tr|K7ESQ2|K7ESQ2_HUMAN" 7 895.4512 2.31 92775 3192 2 895.44893 448.7329 Kinetochore protein Spc24 OS=Homo sapiens OX=9606 GN=SPC24 PE=1 SV=2 5.4 1268.3 - 1.41E+07 - - - -2.5116 - 1.615 0.231 - 361.9 1 2 0 -0.0022 7 0 0 0 6.39E+08 2.77E+08 - - - 2.2653 0.9917 221125_WJC_METTL3_EV_vs_WT_F07.03197.03197.2 0.41 14-Jul K.HIAEDADR.K "sp|P09493|TPM1_HUMAN,tr|A0A494C0V8|A0A494C0V8_HUMAN,tr|A0A0S2Z4G6|A0A0S2Z4G6_HUMAN,tr|F5H7S3|F5H7S3_HUMAN,tr|H0YKX5|H0YKX5_HUMAN,tr|Q6ZN40|Q6ZN40_HUMAN,tr|H0YL42|H0YL42_HUMAN,tr|H0YKJ4|H0YKJ4_HUMAN,tr|H0YK48|H0YK48_HUMAN,tr|B7Z596|B7Z596_HUMAN,tr|A0A494BZZ2|A0A494BZZ2_HUMAN,tr|H7BYY1|H7BYY1_HUMAN" 12 925.4254 1.01 92778 3197 2 925.422233 463.72 Tropomyosin alpha-1 chain OS=Homo sapiens OX=9606 GN=TPM1 PE=1 SV=2 4.54 1268.8 - 1.46E+06 - - - -3.3779 - 1.47 0.253 - 183.7 1 2 0 -0.0031 8 0 0 0 1.03E+08 1.02E+08 - - - 2.0706 0.9921 221125_WJC_METTL3_EV_vs_WT_F07.03204.03204.2 0.0428 18-May K.NGAEQTSTVK[136.11].L sp|Q14703|MBTP1_HUMAN 1 1041.5182 1.25 92783 3204 2 1041.516468 521.7664 Membrane-bound transcription factor site-1 protease OS=Homo sapiens OX=9606 GN=MBTPS1 PE=1 SV=1 6 1269.8 - 209231 - - - -1.6658 - 1.159 0.25 - 47.1 2 2 0 -0.0017 10 0 0 0 1.33E+07 1.06E+07 - - - 1.1644 0.7969 221125_WJC_METTL3_EV_vs_WT_F07.03207.03207.2 0.0732 14-Jul A.KLAEQAER.Y "sp|P31946|1433B_HUMAN,sp|P62258|1433E_HUMAN,sp|P27348|1433T_HUMAN,sp|P63104|1433Z_HUMAN,sp|P31947|1433S_HUMAN,tr|E7EX29|E7EX29_HUMAN,tr|Q4VY19|Q4VY19_HUMAN,tr|B4DJF2|B4DJF2_HUMAN,tr|I3L0W5|I3L0W5_HUMAN,tr|Q4VY20|Q4VY20_HUMAN,tr|E5RIR4|E5RIR4_HUMAN,tr|E9PG15|E9PG15_HUMAN,tr|I3L3T1|I3L3T1_HUMAN,tr|E7EVZ2|E7EVZ2_HUMAN,tr|E5RGE1|E5RGE1_HUMAN,tr|E9PD24|E9PD24_HUMAN,tr|A0A0J9YWE8|A0A0J9YWE8_HUMAN,tr|E7ESK7|E7ESK7_HUMAN" 18 943.5087 1.32 92784 3207 2 943.506346 472.7616 14-3-3 protein beta\alpha OS=Homo sapiens OX=9606 GN=YWHAB PE=1 SV=3 6.14 1270.1 - 732545 - - - -2.4886 - 1.63 0.214 - 207.9 1 1 0 -0.0023 8 0 0 0 1.71E+07 1.29E+07 - - - 2.0944 0.999 221125_WJC_METTL3_EV_vs_WT_F07.03209.03209.2 0.123 16-Sep K.NSAVTSSAR.G sp|Q9Y6D9|MD1L1_HUMAN 1 891.441 1.78 92785 3209 2 891.438988 446.7278 Mitotic spindle assembly checkpoint protein MAD1 OS=Homo sapiens OX=9606 GN=MAD1L1 PE=1 SV=2 9.75 1270.4 - 3.48E+06 - - - -2.2671 - 1.924 0.316 - 425.4 1 2 0 -0.002 9 0 0 0 2.22E+08 1.25E+08 - - - 3.2676 0.9987 221125_WJC_METTL3_EV_vs_WT_F07.03215.03215.2 0.0969 14-Jul K.QIEAQQNK.Q sp|Q9H6T3|RPAP3_HUMAN 1 957.488 1.41 92789 3215 2 957.48653 479.7513 RNA polymerase II-associated protein 3 OS=Homo sapiens OX=9606 GN=RPAP3 PE=1 SV=2 6 1271 - 1.63E+06 - - - -1.4924 - 1.412 0.333 - 199.4 1 2 0 -0.0014 8 0 0 0 3.51E+07 2.49E+07 - - - 2.5406 0.9553 221125_WJC_METTL3_EV_vs_WT_F07.03216.03216.2 0.462 16-Jul K.VVSETNDTK[136.11].V sp|P05783|K1C18_HUMAN 1 999.4964 1.11 92790 3216 2 999.492387 500.7555 "Keratin, type I cytoskeletal 18 OS=Homo sapiens OX=9606 GN=KRT18 PE=1 SV=2" 4.37 1271.1 - 388152 - - - -4.02 - 1.365 0.177 - 141.9 2 2 0 -0.004 9 0 0 0 5.78E+07 5.21E+07 - - - 1.1128 0.8845 221125_WJC_METTL3_EV_vs_WT_F07.03236.03236.2 0.321 12-Jul L.AVVPSK[136.11]R[166.11].Q "sp|P0DMR1|HNRC4_HUMAN,sp|P07910|HNRPC_HUMAN,sp|O60812|HNRC1_HUMAN,sp|B2RXH8|HNRC2_HUMAN,sp|B7ZW38|HNRC3_HUMAN,tr|B4DY08|B4DY08_HUMAN,tr|G3V575|G3V575_HUMAN,tr|G3V5V7|G3V5V7_HUMAN,tr|B2R5W2|B2R5W2_HUMAN,tr|G3V4C1|G3V4C1_HUMAN,tr|A0A0G2JPF8|A0A0G2JPF8_HUMAN,tr|G3V576|G3V576_HUMAN,tr|G3V2D6|G3V2D6_HUMAN,tr|G3V4W0|G3V4W0_HUMAN,tr|G3V555|G3V555_HUMAN,tr|G3V2Q1|G3V2Q1_HUMAN" 16 773.4878 0.001 92797 3236 2 773.486222 387.7512 Heterogeneous nuclear ribonucleoprotein C-like 4 OS=Homo sapiens OX=9606 GN=HNRNPCL4 PE=3 SV=1 11 1273.9 - 1.03E+07 - - - -2.0957 - 1.522 0.278 - 286.9 1 1 0 -0.0016 7 0 0 0 0.00E+00 3.50E+08 - - - 2.4247 0.9438 221125_WJC_METTL3_EV_vs_WT_F07.03245.03245.2 0.097 12-May R.SYSESEK.Q sp|Q96HQ2|C2AIL_HUMAN 1 828.3501 1.19 92802 3245 2 828.348143 415.1823 CDKN2AIP N-terminal-like protein OS=Homo sapiens OX=9606 GN=CDKN2AIPNL PE=1 SV=1 4.53 1274.8 - 1.47E+06 - - - -2.3963 - 0.917 0.187 - 92.1 1 2 0 -0.002 7 0 0 0 3.75E+07 3.15E+07 - - - 0.147 0.999 221125_WJC_METTL3_EV_vs_WT_F07.03246.03246.2 0.022 16-Aug R.QVDTGNTGR[166.11].V "sp|P42566|EPS15_HUMAN,tr|S4R3U1|S4R3U1_HUMAN,tr|B1AUU8|B1AUU8_HUMAN" 3 956.4551 1.24 92803 3246 2 956.453149 479.2348 Epidermal growth factor receptor substrate 15 OS=Homo sapiens OX=9606 GN=EPS15 PE=1 SV=2 5.84 1274.9 - 728816 - - - -2.0315 - 1.755 0.338 - 259.4 1 2 0 -0.0019 9 0 0 0 2.08E+07 1.68E+07 - - - 3.1641 0.9987 221125_WJC_METTL3_EV_vs_WT_F07.03257.03257.2 0.0205 12-Jul R.NQGGYDR.Y sp|P98179|RBM3_HUMAN 1 808.3464 0.98 92808 3257 2 808.34491 405.1805 RNA-binding protein 3 OS=Homo sapiens OX=9606 GN=RBM3 PE=1 SV=1 5.84 1276.4 - 2.84E+06 - - - -1.8185 - 1.464 0.338 - 301 1 2 0 -0.0015 7 0 0 0 2.82E+08 2.89E+08 - - - 2.7448 0.9656 221125_WJC_METTL3_EV_vs_WT_F07.03258.03258.2 0.0689 14-Jul R.LK[136.11]EAEEER[166.11].L "sp|Q96EA4|SPDLY_HUMAN,tr|D6RIF7|D6RIF7_HUMAN,tr|D6RDK5|D6RDK5_HUMAN,tr|D6RC83|D6RC83_HUMAN,tr|D6R936|D6R936_HUMAN,tr|D6REZ1|D6REZ1_HUMAN,tr|D6RIB8|D6RIB8_HUMAN,tr|D6RCL1|D6RCL1_HUMAN" 8 1020.5207 0.05 92809 3258 2 1020.517377 511.2676 Protein Spindly OS=Homo sapiens OX=9606 GN=SPDL1 PE=1 SV=2 4.49 1276.6 - 481436 - - - -3.216 - 1.759 0.283 - 147.3 1 2 1 -0.0033 8 0 0 0 6.04E+05 1.19E+07 - - - 2.8335 0.9908 221125_WJC_METTL3_EV_vs_WT_F07.03259.03259.2 0.589 14-Aug K.SLQDQGSK.A "sp|Q86VS8|HOOK3_HUMAN,tr|H0YDM4|H0YDM4_HUMAN" 2 861.4192 0.67 92810 3259 2 861.417304 431.7169 Protein Hook homolog 3 OS=Homo sapiens OX=9606 GN=HOOK3 PE=1 SV=2 5.55 1276.6 - 1.05E+06 - - - -2.2138 - 1.188 0.239 - 168.5 1 2 0 -0.0019 8 0 0 0 3.52E+07 5.22E+07 - - - 1.3252 0.9875 221125_WJC_METTL3_EV_vs_WT_F07.03265.03265.2 0.141 16-Aug R.QVDTGNTGR.V "sp|P42566|EPS15_HUMAN,tr|S4R3U1|S4R3U1_HUMAN,tr|B1AUU8|B1AUU8_HUMAN" 3 946.4468 0.49 92814 3265 2 946.444409 474.2307 Epidermal growth factor receptor substrate 15 OS=Homo sapiens OX=9606 GN=EPS15 PE=1 SV=2 5.84 1277.3 - 1.29E+06 - - - -2.5495 - 1.342 0.188 - 249.6 1 2 0 -0.0024 9 0 0 0 2.41E+07 4.90E+07 - - - 1.2798 0.9995 221125_WJC_METTL3_EV_vs_WT_F07.03266.03266.2 0.004 12-Jun R.NQGGYDR[166.11].Y sp|P98179|RBM3_HUMAN 1 818.3546 0.98 92815 3266 2 818.35331 410.1846 RNA-binding protein 3 OS=Homo sapiens OX=9606 GN=RBM3 PE=1 SV=1 5.84 1277.3 - 7.05E+06 - - - -1.6374 - 1.54 0.425 - 236.6 1 2 0 -0.0013 7 0 0 0 2.83E+08 2.89E+08 - - - 3.5478 0.9994 221125_WJC_METTL3_EV_vs_WT_F07.03271.03271.2 0.139 14-Sep K.RGQAALDR.L "sp|P40429|RL13A_HUMAN,tr|M0QYS1|M0QYS1_HUMAN,tr|Q8J015|Q8J015_HUMAN,tr|A0A7I2V2L9|A0A7I2V2L9_HUMAN,tr|A0A7I2V5L3|A0A7I2V5L3_HUMAN" 5 885.4781 0.17 92818 3271 2 885.476538 443.7463 60S ribosomal protein L13a OS=Homo sapiens OX=9606 GN=RPL13A PE=1 SV=2 9.6 1277.9 - 6.36E+06 - - - -1.7222 - 1.656 0.38 - 198.9 1 2 0 -0.0015 8 0 0 0 1.56E+08 8.95E+08 - - - 3.3685 0.999 221125_WJC_METTL3_EV_vs_WT_F07.03272.03272.2 0.00578 14-Aug R.QQEQQVAR[166.11].T "sp|Q9HCJ0|TNR6C_HUMAN,tr|A0A1B0GU24|A0A1B0GU24_HUMAN" 2 995.5024 0.92 92819 3272 2 995.500849 498.7585 Trinucleotide repeat-containing gene 6C protein OS=Homo sapiens OX=9606 GN=TNRC6C PE=1 SV=3 6 1278 - 556451 - - - -1.5349 - 1.497 0.348 - 223 1 2 0 -0.0015 8 0 0 0 1.32E+07 1.44E+07 - - - 2.8277 0.9989 221125_WJC_METTL3_EV_vs_WT_F07.03278.03278.2 0.0194 14-Aug R.IQAESGC[160.03]K.L sp|Q96I24|FUBP3_HUMAN 1 891.412 1.54 92822 3278 2 891.411136 446.7133 Far upstream element-binding protein 3 OS=Homo sapiens OX=9606 GN=FUBP3 PE=1 SV=2 5.99 1278.7 - 5.28E+06 - - - -0.9883 - 1.507 0.293 - 182.3 1 2 0 -0.0009 8 0 0 0 1.12E+08 7.30E+07 - - - 2.4417 0.9983 221125_WJC_METTL3_EV_vs_WT_F07.03284.03284.2 0.293 14-Sep K.QLQDQDQK.L sp|Q9NVF7|FBX28_HUMAN 1 1001.4778 1.13 92826 3284 2 1001.477418 501.7462 F-box only protein 28 OS=Homo sapiens OX=9606 GN=FBXO28 PE=1 SV=1 4.21 1279.3 - 987873 - - - -0.3695 - 1.411 0.249 - 314.8 1 2 0 -0.0004 8 0 0 0 1.12E+07 9.91E+06 - - - 1.9184 0.999 221125_WJC_METTL3_EV_vs_WT_F07.03286.03286.2 0.117 14-Sep R.IQAESGC[160.03]K[136.11].L sp|Q96I24|FUBP3_HUMAN 1 899.4262 1.55 92828 3286 2 899.426277 450.7204 Far upstream element-binding protein 3 OS=Homo sapiens OX=9606 GN=FUBP3 PE=1 SV=2 5.99 1279.5 - 4.55E+06 - - - 0.0667 - 1.644 0.25 - 239 1 2 0 0.0001 8 0 0 0 1.13E+08 7.25E+07 - - - 2.3868 0.954 221125_WJC_METTL3_EV_vs_WT_F07.03291.03291.2 0.0145 14-Aug L.VTYADHSK[136.11].L "sp|Q86U44|MTA70_HUMAN,tr|F5H6D8|F5H6D8_HUMAN,tr|H0YFV6|H0YFV6_HUMAN,tr|B4DTN4|B4DTN4_HUMAN" 4 927.4541 0.16 92832 3291 2 927.453745 464.7343 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 6.71 1279.9 - 820173 - - - -0.4324 - 1.446 0.329 - 213.2 1 1 0 -0.0004 8 0 0 0 2.44E+06 1.56E+07 - - - 2.5832 0.9984 221125_WJC_METTL3_EV_vs_WT_F07.03301.03301.2 0.563 14-Aug K.QLQDQDQK[136.11].L sp|Q9NVF7|FBX28_HUMAN 1 1009.492 1.13 92839 3301 2 1009.490849 505.7533 F-box only protein 28 OS=Homo sapiens OX=9606 GN=FBXO28 PE=1 SV=1 4.21 1281.1 - 537031 - - - -1.1283 - 1.418 0.284 - 144.4 1 2 0 -0.0011 8 0 0 0 1.12E+07 9.91E+06 - - - 2.1916 0.9001 221125_WJC_METTL3_EV_vs_WT_F07.03302.03302.2 2.1 14-Aug K.EEPSNNVK[136.11].L "sp|Q14974|IMB1_HUMAN,tr|J3KTM9|J3KTM9_HUMAN,tr|J3QRG4|J3QRG4_HUMAN" 3 923.444 2.03 92840 3302 2 923.442217 462.7293 Importin subunit beta-1 OS=Homo sapiens OX=9606 GN=KPNB1 PE=1 SV=2 4.53 1281.2 - 612804 - - - -1.9037 - 1.074 0.038 - 253.2 1 2 0 -0.0018 8 0 0 0 1.02E+08 5.03E+07 - - - -0.4636 0.9995 221125_WJC_METTL3_EV_vs_WT_F07.03303.03303.2 0.0206 12-Nov K.RPLQEDR.L "sp|O95785|WIZ_HUMAN,tr|A0A669KBG4|A0A669KBG4_HUMAN,tr|A0A2R8YFV2|A0A2R8YFV2_HUMAN,tr|A0A669KAV7|A0A669KAV7_HUMAN,tr|M0QXA7|M0QXA7_HUMAN,tr|A0A669KBH9|A0A669KBH9_HUMAN,tr|B9EGQ5|B9EGQ5_HUMAN" 7 912.4777 1.61 92841 3303 2 912.476011 457.2461 Protein Wiz OS=Homo sapiens OX=9606 GN=WIZ PE=1 SV=2 6.07 1281.3 - 1.23E+06 - - - -1.8817 - 2.14 0.316 - 491.8 1 2 0 -0.0017 7 0 0 0 7.23E+07 4.49E+07 - - - 3.7851 0.9998 221125_WJC_METTL3_EV_vs_WT_F07.03305.03305.2 0.000131 18-Oct R.QLAEAHAQAK.A sp|Q15149|PLEC_HUMAN 1 1065.5567 1.82 92843 3305 2 1065.555397 533.7856 Plectin OS=Homo sapiens OX=9606 GN=PLEC PE=1 SV=3 6.75 1281.5 - 472805 - - - -1.2294 - 1.938 0.494 - 394.7 1 2 0 -0.0013 10 0 0 0 5.60E+06 3.09E+06 - - - 4.5362 0.9999 221125_WJC_METTL3_EV_vs_WT_F07.03310.03310.2 7.00E-06 16-Nov R.C[160.03]GESGHLAR[166.11].E sp|P62633|CNBP_HUMAN 1 995.4482 0.58 92846 3310 2 995.447574 498.7314 CCHC-type zinc finger nucleic acid binding protein OS=Homo sapiens OX=9606 GN=CNBP PE=1 SV=1 6.74 1282.2 - 1.07E+06 - - - -0.662 - 2.315 0.544 - 680.6 1 2 0 -0.0007 9 0 0 0 3.73E+07 6.37E+07 - - - 5.4872 0.9869 221125_WJC_METTL3_EV_vs_WT_F07.03311.03311.2 0.898 16-Aug R.GRPAATEVK.L sp|O75475|PSIP1_HUMAN 1 927.5138 1.18 92847 3311 2 927.512656 464.7642 PC4 and SFRS1-interacting protein OS=Homo sapiens OX=9606 GN=PSIP1 PE=1 SV=1 8.75 1282.3 - 837511 - - - -1.2118 - 1.53 0.048 - 277 1 2 0 -0.0011 9 0 0 0 1.25E+07 1.06E+07 - - - 0.6255 1 221125_WJC_METTL3_EV_vs_WT_F07.03312.03312.2 0.00419 16-Oct R.C[160.03]GESGHLAR.E sp|P62633|CNBP_HUMAN 1 985.44 0.58 92848 3312 2 985.438454 493.7273 CCHC-type zinc finger nucleic acid binding protein OS=Homo sapiens OX=9606 GN=CNBP PE=1 SV=1 6.74 1282.4 - 639530 - - - -1.5313 - 2.313 0.582 - 622.5 1 2 0 -0.0015 9 0 0 0 3.73E+07 6.43E+07 - - - 5.7651 0.9993 221125_WJC_METTL3_EV_vs_WT_F07.03313.03313.2 0.0229 18-Aug R.QLAEAHAQAK[136.11].A sp|Q15149|PLEC_HUMAN 1 1073.5709 1.82 92849 3313 2 1073.570031 537.7927 Plectin OS=Homo sapiens OX=9606 GN=PLEC PE=1 SV=3 6.75 1282.6 - 319398 - - - -0.816 - 1.513 0.354 - 133.9 1 2 0 -0.0009 10 0 0 0 5.60E+06 3.09E+06 - - - 2.8112 0.9812 221125_WJC_METTL3_EV_vs_WT_F07.03317.03317.2 0.506 12-Jun R.SK[136.11]PQLAR[166.11].Y "sp|Q9UBB5|MBD2_HUMAN,sp|O95983|MBD3_HUMAN,tr|X6RBL6|X6RBL6_HUMAN" 3 816.4937 1.73 92851 3317 2 816.493052 409.2541 Methyl-CpG-binding domain protein 2 OS=Homo sapiens OX=9606 GN=MBD2 PE=1 SV=1 11 1283.1 - 6.75E+06 - - - -0.7397 - 1.175 0.113 - 112.1 2 2 0 -0.0006 7 0 0 0 3.65E+08 2.11E+08 - - - 0.2519 0.999 221125_WJC_METTL3_EV_vs_WT_F07.03318.03318.2 0.04 16-Jul K.ATGSEVSQR.K sp|P15924|DESP_HUMAN 1 933.4516 10.5 92852 3318 2 933.451198 467.7331 Desmoplakin OS=Homo sapiens OX=9606 GN=DSP PE=1 SV=3 6.05 1283.1 - 3.20E+06 - - - -0.4017 - 1.341 0.334 - 185.9 1 2 0 -0.0004 9 0 0 0 3.36E+08 3.20E+07 - - - 2.3567 0.9722 221125_WJC_METTL3_EV_vs_WT_F07.03322.03322.2 3.17 14-Aug K.LQEEER[166.11]ER[166.11].R "sp|P08708|RS17_HUMAN,tr|H3BNC9|H3BNC9_HUMAN,tr|H0YN88|H0YN88_HUMAN,tr|A0A075B716|A0A075B716_HUMAN" 4 1107.5423 1.5 92856 3322 2 1107.541799 554.7784 40S ribosomal protein S17 OS=Homo sapiens OX=9606 GN=RPS17 PE=1 SV=2 4.49 1283.4 - 1.73E+06 - - - -0.4894 - 1.625 0.151 - 114.7 1 2 1 -0.0005 8 0 0 0 7.97E+07 5.31E+07 - - - 1.6204 0.9785 221125_WJC_METTL3_EV_vs_WT_F07.03323.03323.2 3.43 14-Aug K.LQEEERER.R "sp|P08708|RS17_HUMAN,tr|H3BNC9|H3BNC9_HUMAN,tr|H0YN88|H0YN88_HUMAN,tr|A0A075B716|A0A075B716_HUMAN" 4 1087.5258 1.5 92857 3323 2 1087.524882 544.7702 40S ribosomal protein S17 OS=Homo sapiens OX=9606 GN=RPS17 PE=1 SV=2 4.49 1283.5 - 1.61E+06 - - - -0.845 - 1.558 0.207 - 110.2 1 2 1 -0.0009 8 0 0 0 7.97E+07 5.30E+07 - - - 1.9069 0.9947 221125_WJC_METTL3_EV_vs_WT_F07.03326.03326.2 0.0523 16-May R.ADC[160.03]GPGEGR.S sp|P31274|HXC9_HUMAN 1 917.3661 2.33 92860 3326 2 917.364682 459.6903 Homeobox protein Hox-C9 OS=Homo sapiens OX=9606 GN=HOXC9 PE=1 SV=3 4.37 1283.8 - 759702 - - - -1.5773 - 1.272 0.227 - 106.4 1 2 0 -0.0014 9 0 0 0 2.69E+07 1.16E+07 - - - 1.4132 0.9925 221125_WJC_METTL3_EV_vs_WT_F07.03333.03333.2 0.00187 14-Sep R.VFK[136.11]EENQK[136.11].G "sp|Q9NYF8|BCLF1_HUMAN,tr|E9PKI6|E9PKI6_HUMAN,tr|A0A1W2PQ43|A0A1W2PQ43_HUMAN,tr|E9PK91|E9PK91_HUMAN,tr|E9PK09|E9PK09_HUMAN,tr|E9PQN2|E9PQN2_HUMAN" 6 1036.5524 2.2 92865 3333 2 1036.551919 519.2835 Bcl-2-associated transcription factor 1 OS=Homo sapiens OX=9606 GN=BCLAF1 PE=1 SV=2 6.11 1284.4 - 3.12E+06 - - - -0.4737 - 1.551 0.323 - 282 1 2 1 -0.0005 8 0 0 0 1.45E+09 6.60E+08 - - - 2.7502 0.9993 221125_WJC_METTL3_EV_vs_WT_F07.03334.03334.2 0.0788 14-Sep K.K[136.11]GAAIPAK[136.11].G "sp|P19338|NUCL_HUMAN,tr|A0A7I2V506|A0A7I2V506_HUMAN,tr|A0A7I2V699|A0A7I2V699_HUMAN,tr|A0A7I2V2U7|A0A7I2V2U7_HUMAN,tr|A0A7I2V3F3|A0A7I2V3F3_HUMAN,tr|A0A7I2V428|A0A7I2V428_HUMAN,tr|A0A7I2V349|A0A7I2V349_HUMAN,tr|H7BY16|H7BY16_HUMAN,tr|A0A7I2V5M5|A0A7I2V5M5_HUMAN,tr|A0A7I2V2S8|A0A7I2V2S8_HUMAN,tr|C9JLB1|C9JLB1_HUMAN" 11 770.4985 0.001 92866 3334 2 770.498177 386.2565 Nucleolin OS=Homo sapiens OX=9606 GN=NCL PE=1 SV=3 10 1284.5 - 2.73E+06 - - - -0.4504 - 1.79 0.266 - 252.3 1 2 0 -0.0003 8 0 0 0 0.00E+00 1.88E+08 - - - 2.7615 0.9059 221125_WJC_METTL3_EV_vs_WT_F07.03345.03345.2 1.37 14-Aug K.SIR[166.11]DTPAK[136.11].N "sp|P06748|NPM_HUMAN,tr|E5RI98|E5RI98_HUMAN,tr|A0A7I2YQC0|A0A7I2YQC0_HUMAN,tr|A0A7I2V5S2|A0A7I2V5S2_HUMAN" 4 904.5097 0.94 92875 3345 2 904.507713 453.2621 Nucleophosmin OS=Homo sapiens OX=9606 GN=NPM1 PE=1 SV=2 8.46 1285.7 - 4.18E+06 - - - -2.1979 - 1.445 0.158 - 238.7 1 2 1 -0.002 8 0 0 0 6.46E+07 6.87E+07 - - - 1.3176 0.9808 221125_WJC_METTL3_EV_vs_WT_F07.03351.03351.2 0.22 14-Aug R.QVRPVTEK.L "sp|P38606|VATA_HUMAN,tr|C9JVW8|C9JVW8_HUMAN" 2 955.5451 1.58 92879 3351 2 955.543821 478.7798 V-type proton ATPase catalytic subunit A OS=Homo sapiens OX=9606 GN=ATP6V1A PE=1 SV=2 8.75 1286.3 - 1.36E+06 - - - -1.3176 - 1.615 0.007 - 171.4 2 2 0 -0.0013 8 0 0 0 1.87E+07 1.19E+07 - - - 0.4035 0.9999 221125_WJC_METTL3_EV_vs_WT_F07.03356.03356.2 0.000375 18-Dec R.STAVTTSSAK.L "sp|Q9UKM9|RALY_HUMAN,tr|Q5QPM0|Q5QPM0_HUMAN,tr|Q5QPM1|Q5QPM1_HUMAN,tr|Q5QPL9|Q5QPL9_HUMAN" 4 951.4873 1.18 92881 3356 2 951.48697 476.7509 RNA-binding protein Raly OS=Homo sapiens OX=9606 GN=RALY PE=1 SV=1 8.47 1287 - 1.60E+06 - - - -0.3363 - 2.289 0.44 - 727.4 1 2 0 -0.0003 10 0 0 0 5.38E+08 4.55E+08 - - - 4.6023 0.9987 221125_WJC_METTL3_EV_vs_WT_F07.03357.03357.2 0.0152 12-Jul R.HGGFSDR[166.11].S "sp|Q6P4I2|WDR73_HUMAN,tr|H0YMT3|H0YMT3_HUMAN,tr|H0YLH0|H0YLH0_HUMAN" 3 784.3492 1.04 92882 3357 2 784.347656 393.1819 WD repeat-containing protein 73 OS=Homo sapiens OX=9606 GN=WDR73 PE=1 SV=1 6.74 1287.1 - 1.51E+06 - - - -1.9315 - 1.32 0.392 - 110.5 1 2 0 -0.0015 7 0 0 0 3.51E+07 3.37E+07 - - - 2.8155 0.9936 221125_WJC_METTL3_EV_vs_WT_F07.03363.03363.2 0.00766 16-Oct K.ITDK[136.11]EAAER[166.11].L "sp|Q9NQG5|RPR1B_HUMAN,tr|A2A2M0|A2A2M0_HUMAN" 2 1049.5472 2.72 92886 3363 2 1049.54492 525.7809 Regulation of nuclear pre-mRNA domain-containing protein 1B OS=Homo sapiens OX=9606 GN=RPRD1B PE=1 SV=1 4.68 1287.7 - 2.36E+06 - - - -2.18 - 1.884 0.407 - 441.1 1 2 1 -0.0023 9 0 0 0 1.32E+08 4.86E+07 - - - 3.8788 0.9722 221125_WJC_METTL3_EV_vs_WT_F07.03368.03368.2 0.963 12-Jun K.LTDDVKK.E "sp|Q13435|SF3B2_HUMAN,tr|E9PPJ0|E9PPJ0_HUMAN" 2 817.4545 0.93 92889 3368 2 817.452776 409.7345 Splicing factor 3B subunit 2 OS=Homo sapiens OX=9606 GN=SF3B2 PE=1 SV=2 5.96 1288.2 - 6.32E+06 - - - -2.1494 - 1.121 0.15 - 86.5 1 2 0 -0.0018 7 0 0 0 9.56E+07 1.03E+08 - - - 0.5103 0.9993 221125_WJC_METTL3_EV_vs_WT_F07.03377.03377.2 0.0325 14-Aug R.KAAELQAR.L sp|O43395|PRPF3_HUMAN 1 885.5032 2.24 92896 3377 2 885.501798 443.7589 U4\U6 small nuclear ribonucleoprotein Prp3 OS=Homo sapiens OX=9606 GN=PRPF3 PE=1 SV=2 8.75 1289.1 - 2.64E+07 - - - -1.6002 - 1.724 0.333 - 228.4 1 2 0 -0.0014 8 0 0 0 6.98E+08 3.12E+08 - - - 3.1427 0.9745 221125_WJC_METTL3_EV_vs_WT_F07.03379.03379.2 0.445 12-May R.EESAHLR[166.11].E sp|Q9Y6D9|MD1L1_HUMAN 1 850.4172 2.38 92897 3379 2 850.414626 426.2159 Mitotic spindle assembly checkpoint protein MAD1 OS=Homo sapiens OX=9606 GN=MAD1L1 PE=1 SV=2 5.4 1289.3 - 1.48E+06 - - - -3.0855 - 1.12 0.222 - 122.8 1 2 0 -0.0026 7 0 0 0 8.15E+07 3.42E+07 - - - 1.039 0.9973 221125_WJC_METTL3_EV_vs_WT_F07.03383.03383.2 0.0728 12-May R.GTFHDDR.D "tr|H0YF63|H0YF63_HUMAN,tr|E9PK91|E9PK91_HUMAN" 2 846.362 0.77 92899 3383 2 846.361038 424.1883 Bcl-2-associated transcription factor 1 (Fragment) OS=Homo sapiens OX=9606 GN=BCLAF1 PE=1 SV=1 5.21 1289.7 - 2.63E+06 - - - -1.1721 - 1.272 0.264 - 167.7 1 2 0 -0.001 7 0 0 0 9.72E+07 1.26E+08 - - - 1.7529 0.9994 221125_WJC_METTL3_EV_vs_WT_F07.03391.03391.2 0.00189 16-Sep R.GTAQYSSQK.S sp|Q99959|PKP2_HUMAN 1 968.4563 0.55 92903 3391 2 968.454799 485.2354 Plakophilin-2 OS=Homo sapiens OX=9606 GN=PKP2 PE=1 SV=2 8.59 1290.7 - 978074 - - - -1.5747 - 1.847 0.343 - 400.2 1 2 0 -0.0015 9 0 0 0 4.12E+07 7.48E+07 - - - 3.349 0.9998 221125_WJC_METTL3_EV_vs_WT_F07.03392.03392.2 0.00392 16-Oct K.QVAQQEAQR.A "sp|Q99623|PHB2_HUMAN,tr|F5H3X6|F5H3X6_HUMAN,tr|F5GWA7|F5GWA7_HUMAN,tr|F5GY37|F5GY37_HUMAN" 4 1056.5312 1.19 92904 3392 2 1056.530909 529.2729 Prohibitin-2 OS=Homo sapiens OX=9606 GN=PHB2 PE=1 SV=2 6 1290.8 - 1.00E+06 - - - -0.2953 - 2.014 0.372 - 567.5 1 2 0 -0.0003 9 0 0 0 7.50E+08 6.29E+08 - - - 3.814 0.9996 221125_WJC_METTL3_EV_vs_WT_F07.03396.03396.2 0.00806 14-Aug K.HIAEEADR.K "sp|P67936|TPM4_HUMAN,sp|P06753|TPM3_HUMAN,tr|A0A2R8Y5V9|A0A2R8Y5V9_HUMAN,tr|A0A5F9UN72|A0A5F9UN72_HUMAN,tr|A0A2R8YEU4|A0A2R8YEU4_HUMAN,tr|A0A2R8YGX3|A0A2R8YGX3_HUMAN,tr|A0A2R2Y2Q3|A0A2R2Y2Q3_HUMAN,tr|A0A087WWU8|A0A087WWU8_HUMAN,tr|K7ENT6|K7ENT6_HUMAN,tr|J3KN67|J3KN67_HUMAN,tr|A0A494C0P6|A0A494C0P6_HUMAN,tr|A0A2R8YH90|A0A2R8YH90_HUMAN,tr|A0A2R8YE05|A0A2R8YE05_HUMAN,tr|A0A2R8YHD2|A0A2R8YHD2_HUMAN" 14 939.441 1.27 92906 3396 2 939.440295 470.7278 Tropomyosin alpha-4 chain OS=Homo sapiens OX=9606 GN=TPM4 PE=1 SV=3 4.65 1291.2 - 7.73E+06 - - - -0.76 - 1.713 0.348 - 246.5 1 2 0 -0.0007 8 0 0 0 5.19E+08 4.08E+08 - - - 3.2344 0.9995 221125_WJC_METTL3_EV_vs_WT_F07.03397.03397.2 0.000726 16-Oct K.AAETC[160.03]QEPK[136.11].E sp|Q9P032|NDUF4_HUMAN 1 1040.4688 1.77 92907 3397 2 1040.467184 521.2417 NADH dehydrogenase [ubiquinone] 1 alpha subcomplex assembly factor 4 OS=Homo sapiens OX=9606 GN=NDUFAF4 PE=1 SV=1 4.53 1291.3 - 5.43E+06 - - - -1.5628 - 1.592 0.442 - 429.6 1 2 0 -0.0016 9 0 0 0 3.20E+08 1.81E+08 - - - 3.6503 0.9983 221125_WJC_METTL3_EV_vs_WT_F07.03402.03402.2 0.121 12-Jun K.IC[160.03]DVNHR.D "sp|Q6W2J9|BCOR_HUMAN,tr|H7BZ37|H7BZ37_HUMAN,tr|H7C2V9|H7C2V9_HUMAN,tr|H7C231|H7C231_HUMAN" 4 912.4236 2.59 92910 3402 2 912.422421 457.2191 BCL-6 corepressor OS=Homo sapiens OX=9606 GN=BCOR PE=1 SV=1 6.74 1291.8 - 1.77E+06 - - - -1.2757 - 1.312 0.307 - 125.6 1 2 0 -0.0012 7 0 0 0 5.63E+07 2.17E+07 - - - 2.1686 0.9925 221125_WJC_METTL3_EV_vs_WT_F07.03409.03409.2 8.54E-05 18-Dec R.PGIGATHSSR.F "sp|P62841|RS15_HUMAN,tr|K7EM56|K7EM56_HUMAN,tr|A0A0B4J2B4|A0A0B4J2B4_HUMAN,tr|K7ELC2|K7ELC2_HUMAN,tr|K7EQJ5|K7EQJ5_HUMAN,tr|S4R417|S4R417_HUMAN" 6 981.4992 1.45 92915 3409 2 981.498136 491.7569 40S ribosomal protein S15 OS=Homo sapiens OX=9606 GN=RPS15 PE=1 SV=2 10.18 1292.4 - 6.24E+06 - - - -1.0759 - 2.481 0.491 - 566.8 1 1 0 -0.0011 10 0 0 0 2.35E+08 1.62E+08 - - - 5.2035 0.9966 221125_WJC_METTL3_EV_vs_WT_F07.03413.03413.2 0.0173 12-Jun K.SDAEFK[136.11]K[136.11].L sp|Q5T3J3|LRIF1_HUMAN 1 839.436 3.41 92919 3413 2 839.433935 420.7253 Ligand-dependent nuclear receptor-interacting factor 1 OS=Homo sapiens OX=9606 GN=LRIF1 PE=1 SV=1 5.79 1292.6 - 1.47E+06 - - - -2.4397 - 1.366 0.299 - 148.2 1 2 0 -0.002 7 0 0 0 7.90E+07 2.32E+07 - - - 2.237 0.9995 221125_WJC_METTL3_EV_vs_WT_F07.03417.03417.2 0.00376 14-Sep K.HIAEEADR[166.11].K "sp|P67936|TPM4_HUMAN,sp|P06753|TPM3_HUMAN,tr|A0A2R8Y5V9|A0A2R8Y5V9_HUMAN,tr|A0A5F9UN72|A0A5F9UN72_HUMAN,tr|A0A2R8YEU4|A0A2R8YEU4_HUMAN,tr|A0A2R8YGX3|A0A2R8YGX3_HUMAN,tr|A0A2R2Y2Q3|A0A2R2Y2Q3_HUMAN,tr|A0A087WWU8|A0A087WWU8_HUMAN,tr|K7ENT6|K7ENT6_HUMAN,tr|J3KN67|J3KN67_HUMAN,tr|A0A494C0P6|A0A494C0P6_HUMAN,tr|A0A2R8YH90|A0A2R8YH90_HUMAN,tr|A0A2R8YE05|A0A2R8YE05_HUMAN,tr|A0A2R8YHD2|A0A2R8YHD2_HUMAN" 14 949.4493 1.27 92921 3417 2 949.447377 475.7319 Tropomyosin alpha-4 chain OS=Homo sapiens OX=9606 GN=TPM4 PE=1 SV=3 4.65 1293.1 - 2.07E+07 - - - -2.0033 - 1.705 0.43 - 302.7 1 2 0 -0.0019 8 0 0 0 5.15E+08 4.05E+08 - - - 3.8256 0.9364 221125_WJC_METTL3_EV_vs_WT_F07.03419.03419.2 4.09 12-Jun K.TDQNYEK[136.11].M "sp|Q9P2J5|SYLC_HUMAN,tr|A0A6I8PIV1|A0A6I8PIV1_HUMAN,tr|A0A6I8PRS0|A0A6I8PRS0_HUMAN,tr|A0A6I8PLB8|A0A6I8PLB8_HUMAN,tr|A0A6I8PIT3|A0A6I8PIT3_HUMAN,tr|A0A6I8PLB3|A0A6I8PLB3_HUMAN,tr|A0A6I8PS05|A0A6I8PS05_HUMAN,tr|B4DER1|B4DER1_HUMAN,tr|A0A6I8PL42|A0A6I8PL42_HUMAN" 9 904.4018 0.99 92923 3419 2 904.399885 453.2082 "Leucine--tRNA ligase, cytoplasmic OS=Homo sapiens OX=9606 GN=LARS1 PE=1 SV=2" 4.37 1293.2 - 5.92E+06 - - - -2.0909 - 1.042 0.102 - 84.4 1 2 0 -0.0019 7 0 0 0 7.37E+07 7.46E+07 - - - -0.0759 0.9965 221125_WJC_METTL3_EV_vs_WT_F07.03424.03424.2 0.168 12-Jul K.SDLEDK[136.11]R[166.11].Q "sp|P11233|RALA_HUMAN,tr|H7C3P7|H7C3P7_HUMAN" 2 879.4417 1.19 92926 3424 2 879.440112 440.7281 Ras-related protein Ral-A OS=Homo sapiens OX=9606 GN=RALA PE=1 SV=1 4.56 1293.8 - 2.46E+06 - - - -1.7841 - 1.441 0.222 - 280.2 1 2 0 -0.0016 7 0 0 0 1.98E+08 1.67E+08 - - - 1.8378 0.9902 221125_WJC_METTL3_EV_vs_WT_F07.03431.03431.2 6.92E-06 18-Dec R.PGIGATHSSR[166.11].F "sp|P62841|RS15_HUMAN,tr|K7EM56|K7EM56_HUMAN,tr|A0A0B4J2B4|A0A0B4J2B4_HUMAN,tr|K7ELC2|K7ELC2_HUMAN,tr|K7EQJ5|K7EQJ5_HUMAN,tr|S4R417|S4R417_HUMAN" 6 991.5075 1.46 92930 3431 2 991.505724 496.761 40S ribosomal protein S15 OS=Homo sapiens OX=9606 GN=RPS15 PE=1 SV=2 10.18 1294.5 - 1.06E+07 - - - -1.7529 - 2.921 0.463 - 569 1 1 0 -0.0017 10 0 0 0 2.35E+08 1.61E+08 - - - 5.4522 0.88 221125_WJC_METTL3_EV_vs_WT_F07.03435.03435.2 0.00149 14-Jul K.ASDADR[166.11]PC[160.03].R "sp|Q86U44|MTA70_HUMAN,tr|H0YFV6|H0YFV6_HUMAN" 2 900.3635 0.02 92932 3435 2 900.361016 451.189 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 4.21 1294.9 - 1.48E+07 - - - -2.7589 - 1.545 0.336 - 254.3 1 1 0 -0.0025 8 0 0 0 7.17E+06 3.32E+08 - - - 2.8339 0.9886 221125_WJC_METTL3_EV_vs_WT_F07.03443.03443.2 0.671 14-Aug K.AQQVESER[166.11].A "sp|Q8TCG1|CIP2A_HUMAN,tr|A0A087X211|A0A087X211_HUMAN" 2 955.4598 1.1 92937 3443 2 955.455682 478.7372 Protein CIP2A OS=Homo sapiens OX=9606 GN=CIP2A PE=1 SV=2 4.53 1295.8 - 1.49E+06 - - - -4.355 - 1.887 0.198 - 323.1 1 2 0 -0.0042 8 0 0 0 5.94E+07 5.38E+07 - - - 2.4172 0.9883 221125_WJC_METTL3_EV_vs_WT_F07.03444.03444.2 0.067 16-Sep K.QPPQQPAAK[136.11].L sp|Q9H6F5|CCD86_HUMAN 1 971.528 0.81 92938 3444 2 971.523713 486.7713 Coiled-coil domain-containing protein 86 OS=Homo sapiens OX=9606 GN=CCDC86 PE=1 SV=1 8.75 1295.9 - 965370 - - - -4.3921 - 1.539 0.288 - 180.1 1 2 0 -0.0043 9 0 0 0 1.99E+07 2.46E+07 - - - 2.4141 0.9975 221125_WJC_METTL3_EV_vs_WT_F07.03454.03454.2 0.0236 16-Sep K.SISQQSGAR[166.11].L "sp|Q96AE4|FUBP1_HUMAN,tr|E9PEB5|E9PEB5_HUMAN" 2 942.4758 0.9 92944 3454 2 942.473939 472.2452 Far upstream element-binding protein 1 OS=Homo sapiens OX=9606 GN=FUBP1 PE=1 SV=3 9.47 1297 - 5.17E+06 - - - -2.0043 - 1.597 0.248 - 208.8 1 2 0 -0.0019 9 0 0 0 1.72E+08 1.90E+08 - - - 2.2265 0.9895 221125_WJC_METTL3_EV_vs_WT_F07.03460.03460.2 0.00346 12-Jun R.DSYSSSR.S "sp|Q96E39|RMXL1_HUMAN,sp|P38159|RBMX_HUMAN,tr|H3BUY5|H3BUY5_HUMAN" 3 800.3301 1.42 92948 3460 2 800.329604 401.1723 "RNA binding motif protein, X-linked-like-1 OS=Homo sapiens OX=9606 GN=RBMXL1 PE=1 SV=1" 5.84 1297.6 - 6.60E+06 - - - -0.571 - 1.17 0.146 - 141.7 1 2 0 -0.0005 7 0 0 0 1.66E+09 1.17E+09 - - - 0.6167 0.9937 221125_WJC_METTL3_EV_vs_WT_F07.03468.03468.2 0.0272 12-Aug K.QSQDLNR.S "sp|Q9H019|MFR1L_HUMAN,tr|E9PLD2|E9PLD2_HUMAN" 2 859.4148 1.14 92954 3468 2 859.411778 430.7147 Mitochondrial fission regulator 1-like OS=Homo sapiens OX=9606 GN=MTFR1L PE=1 SV=2 5.84 1298.4 - 8.12E+06 - - - -3.5094 - 1.578 0.258 - 366.8 1 2 0 -0.003 7 0 0 0 2.98E+08 2.61E+08 - - - 2.391 0.9983 221125_WJC_METTL3_EV_vs_WT_F07.03471.03471.2 0.0123 14-Jun R.GEC[160.03]TPTQR.E sp|Q8TEM1|PO210_HUMAN 1 947.4131 2.09 92957 3471 2 947.411448 474.7138 Nuclear pore membrane glycoprotein 210 OS=Homo sapiens OX=9606 GN=NUP210 PE=1 SV=3 5.99 1298.5 - 2.80E+06 - - - -1.7226 - 1.315 0.343 - 179.4 1 2 0 -0.0016 8 0 0 0 1.27E+08 6.06E+07 - - - 2.3998 0.9997 221125_WJC_METTL3_EV_vs_WT_F07.03473.03473.2 8.76E-05 20-Oct K.EVTNASAAGNK[136.11].A sp|Q15054|DPOD3_HUMAN 1 1068.5291 0.2 92959 3473 2 1068.528436 535.2718 DNA polymerase delta subunit 3 OS=Homo sapiens OX=9606 GN=POLD3 PE=1 SV=2 6.1 1298.7 - 1.38E+06 - - - -0.6233 - 1.961 0.366 - 353.2 1 2 0 -0.0007 11 0 0 0 2.02E+07 1.01E+08 - - - 3.5659 0.9495 221125_WJC_METTL3_EV_vs_WT_F07.03475.03475.2 0.000931 16-Sep R.PRPPVSSTK.S sp|Q53F19|NCBP3_HUMAN 1 967.5451 1.27 92961 3475 2 967.543136 484.7798 Nuclear cap-binding protein subunit 3 OS=Homo sapiens OX=9606 GN=NCBP3 PE=1 SV=2 11.01 1298.9 - 947068 - - - -2.0092 - 1.587 0.387 - 287.5 1 1 0 -0.0019 9 0 0 0 1.99E+07 1.56E+07 - - - 3.2349 0.9965 221125_WJC_METTL3_EV_vs_WT_F07.03476.03476.2 0.296 20-Aug R.EGGQTAPASTR.L "sp|P06396|GELS_HUMAN,tr|A0A0A0MS51|A0A0A0MS51_HUMAN,tr|A0A0A0MT01|A0A0A0MT01_HUMAN,tr|Q5T0H8|Q5T0H8_HUMAN" 4 1073.5102 999 92962 3476 2 1073.507668 537.7624 Gelsolin OS=Homo sapiens OX=9606 GN=GSN PE=1 SV=1 6.1 1299.1 - 583676 - - - -2.313 - 1.45 0.284 - 205.5 1 2 0 -0.0025 11 0 0 0 6.98E+06 0.00E+00 - - - 2.143 0.9733 221125_WJC_METTL3_EV_vs_WT_F07.03481.03481.2 0.0458 14-Aug K.LKQVEDEK.N sp|P35579|MYH9_HUMAN 1 987.5237 1.04 92964 3481 2 987.521916 494.7691 Myosin-9 OS=Homo sapiens OX=9606 GN=MYH9 PE=1 SV=4 4.68 1299.7 - 3.69E+06 - - - -1.7822 - 1.644 0.216 - 162 1 2 1 -0.0018 8 0 0 0 6.23E+07 5.97E+07 - - - 2.1352 0.9994 221125_WJC_METTL3_EV_vs_WT_F07.03482.03482.2 0.00304 20-Oct K.EVTNASAAGNK.A sp|Q15054|DPOD3_HUMAN 1 1060.5149 0.2 92965 3482 2 1060.513555 531.2647 DNA polymerase delta subunit 3 OS=Homo sapiens OX=9606 GN=POLD3 PE=1 SV=2 6.1 1299.8 - 586315 - - - -1.2701 - 1.652 0.374 - 265.4 1 2 0 -0.0013 11 0 0 0 2.03E+07 1.01E+08 - - - 3.1609 0.9938 221125_WJC_METTL3_EV_vs_WT_F07.03491.03491.2 0.019 12-Jun K.GQNQDYR.G "sp|P19338|NUCL_HUMAN,tr|A0A7I2V506|A0A7I2V506_HUMAN,tr|A0A7I2V2U7|A0A7I2V2U7_HUMAN,tr|A0A7I2V3F3|A0A7I2V3F3_HUMAN,tr|A0A7I2V428|A0A7I2V428_HUMAN,tr|A0A7I2V349|A0A7I2V349_HUMAN,tr|H7BY16|H7BY16_HUMAN,tr|A0A7I2V5M5|A0A7I2V5M5_HUMAN,tr|C9JLB1|C9JLB1_HUMAN" 9 879.3835 0.99 92969 3491 2 879.380036 440.699 Nucleolin OS=Homo sapiens OX=9606 GN=NCL PE=1 SV=3 5.84 1300.9 - 6.98E+06 - - - -3.9323 - 1.392 0.353 - 226.9 1 2 0 -0.0035 7 0 0 0 7.57E+08 7.61E+08 - - - 2.6951 0.9788 221125_WJC_METTL3_EV_vs_WT_F07.03493.03493.2 0.174 12-May K.GQNQDYR[166.11].G "sp|P19338|NUCL_HUMAN,tr|A0A7I2V506|A0A7I2V506_HUMAN,tr|A0A7I2V2U7|A0A7I2V2U7_HUMAN,tr|A0A7I2V3F3|A0A7I2V3F3_HUMAN,tr|A0A7I2V428|A0A7I2V428_HUMAN,tr|A0A7I2V349|A0A7I2V349_HUMAN,tr|H7BY16|H7BY16_HUMAN,tr|A0A7I2V5M5|A0A7I2V5M5_HUMAN,tr|C9JLB1|C9JLB1_HUMAN" 9 889.3918 1 92971 3493 2 889.389088 445.7032 Nucleolin OS=Homo sapiens OX=9606 GN=NCL PE=1 SV=3 5.84 1301.1 - 1.46E+07 - - - -3.0088 - 1.13 0.231 - 120.1 1 2 0 -0.0027 7 0 0 0 7.57E+08 7.61E+08 - - - 1.1336 0.8401 221125_WJC_METTL3_EV_vs_WT_F07.03501.03501.2 0.0394 16-Jul R.EPGYKAEGK.Y "sp|Q9Y2W1|TR150_HUMAN,tr|A0A3B3ITZ9|A0A3B3ITZ9_HUMAN" 2 977.4818 3.11 92975 3501 2 977.47879 489.7482 Thyroid hormone receptor-associated protein 3 OS=Homo sapiens OX=9606 GN=THRAP3 PE=1 SV=2 6.24 1302.1 - 1.65E+06 - - - -3.0906 - 1.279 0.217 - 160.4 1 2 1 -0.003 9 0 0 0 8.66E+07 2.78E+07 - - - 1.3547 0.9993 221125_WJC_METTL3_EV_vs_WT_F07.03509.03509.2 5.98E-06 16-Nov R.SGGGYGGDR.S "sp|Q92804|RBP56_HUMAN,sp|Q92804|RBP56_HUMAN,sp|Q92804|RBP56_HUMAN,sp|Q92804|RBP56_HUMAN,tr|A0A075B7C1|A0A075B7C1_HUMAN,tr|A0A075B7F4|A0A075B7F4_HUMAN,tr|A0A075B7F4|A0A075B7F4_HUMAN" 7 824.3413 1.02 92978 3509 2 824.340131 413.1779 TATA-binding protein-associated factor 2N OS=Homo sapiens OX=9606 GN=TAF15 PE=1 SV=1 5.55 1303.1 - 1.44E+07 - - - -1.412 - 2.258 0.226 - 607.2 1 2 0 -0.0012 9 0 0 0 7.08E+08 6.95E+08 - - - 3.0662 0.9986 221125_WJC_METTL3_EV_vs_WT_F07.03513.03513.2 0.389 12-Oct K.TDLADKR.Q "sp|P20340|RAB6A_HUMAN,sp|Q9NRW1|RAB6B_HUMAN,sp|Q9H0N0|RAB6C_HUMAN,sp|Q53S08|RAB6D_HUMAN,tr|J3KR73|J3KR73_HUMAN,tr|C9JU14|C9JU14_HUMAN" 6 817.4294 1.53 92980 3513 2 817.428491 409.722 Ras-related protein Rab-6A OS=Homo sapiens OX=9606 GN=RAB6A PE=1 SV=3 5.63 1303.6 - 1.00E+07 - - - -1.0888 - 1.698 0.208 - 471.7 1 2 0 -0.0009 7 0 0 0 3.53E+08 2.31E+08 - - - 2.2546 0.9957 221125_WJC_METTL3_EV_vs_WT_F07.03514.03514.2 0.0809 12-Sep K.HITGSYK[136.11].V sp|Q15046|SYK_HUMAN 1 812.4272 3.46 92981 3514 2 812.425125 407.2209 Lysine--tRNA ligase OS=Homo sapiens OX=9606 GN=KARS1 PE=1 SV=3 8.6 1303.6 - 8.26E+06 - - - -2.5578 - 1.449 0.257 - 273.2 1 2 0 -0.0021 7 0 0 0 7.68E+08 2.22E+08 - - - 2.1137 0.9736 221125_WJC_METTL3_EV_vs_WT_F07.03517.03517.2 0.506 12-Jul K.KALPPEK.K "sp|Q00839|HNRPU_HUMAN,tr|A0A1W2PQL0|A0A1W2PQL0_HUMAN,tr|A0A1W2PPL4|A0A1W2PPL4_HUMAN,tr|A0A087WZF3|A0A087WZF3_HUMAN,tr|Q5RI18|Q5RI18_HUMAN,tr|A0A1W2PP35|A0A1W2PP35_HUMAN,tr|A0A1W2PPS1|A0A1W2PPS1_HUMAN,tr|A0A1W2PPH7|A0A1W2PPH7_HUMAN,tr|A0A1W2PQD4|A0A1W2PQD4_HUMAN,tr|A0A1W2PP34|A0A1W2PP34_HUMAN,tr|A0A1X7SBS1|A0A1X7SBS1_HUMAN" 11 781.4698 1.06 92984 3517 2 781.467952 391.7422 Heterogeneous nuclear ribonucleoprotein U OS=Homo sapiens OX=9606 GN=HNRNPU PE=1 SV=6 8.59 1303.9 - 828083 - - - -2.352 - 1.332 0.094 - 181.3 1 2 0 -0.0018 7 0 0 0 4.35E+07 4.12E+07 - - - 0.6431 0.9956 221125_WJC_METTL3_EV_vs_WT_F07.03522.03522.2 0.108 14-Jul R.GAPQHYPK[136.11].T "sp|P78344|IF4G2_HUMAN,tr|H0YD99|H0YD99_HUMAN,tr|H0YCF8|H0YCF8_HUMAN,tr|H0YEC5|H0YEC5_HUMAN,tr|H0YDC0|H0YDC0_HUMAN,tr|H0YEN8|H0YEN8_HUMAN,tr|H0Y3P2|H0Y3P2_HUMAN,tr|H0YCH5|H0YCH5_HUMAN,tr|H0YD77|H0YD77_HUMAN,tr|D3DQV9|D3DQV9_HUMAN" 10 904.4647 1.99 92987 3522 2 904.462503 453.2396 Eukaryotic translation initiation factor 4 gamma 2 OS=Homo sapiens OX=9606 GN=EIF4G2 PE=1 SV=1 8.6 1304.4 - 2.60E+06 - - - -2.3749 - 1.474 0.241 - 218.8 1 2 0 -0.0021 8 0 0 0 2.26E+08 1.14E+08 - - - 1.9905 0.9952 221125_WJC_METTL3_EV_vs_WT_F07.03529.03529.2 0.217 14-Aug R.NTVVPTK[136.11]K[136.11].S "sp|P11021|BIP_HUMAN,tr|A0A7P0TB36|A0A7P0TB36_HUMAN,tr|A0A7P0TAI0|A0A7P0TAI0_HUMAN" 3 901.5568 0.62 92992 3529 2 901.554809 451.7857 Endoplasmic reticulum chaperone BiP OS=Homo sapiens OX=9606 GN=HSPA5 PE=1 SV=2 10 1305.1 - 3.21E+06 - - - -2.1718 - 1.564 0.191 - 232.2 1 2 0 -0.002 8 0 0 0 1.26E+08 2.02E+08 - - - 1.8 0.9995 221125_WJC_METTL3_EV_vs_WT_F07.03534.03534.2 0.0464 16-Sep R.SGGGYGGDR[166.11].S "sp|Q92804|RBP56_HUMAN,sp|Q92804|RBP56_HUMAN,sp|Q92804|RBP56_HUMAN,sp|Q92804|RBP56_HUMAN,tr|A0A075B7C1|A0A075B7C1_HUMAN,tr|A0A075B7F4|A0A075B7F4_HUMAN,tr|A0A075B7F4|A0A075B7F4_HUMAN" 7 834.3496 1.02 92995 3534 2 834.348566 418.1821 TATA-binding protein-associated factor 2N OS=Homo sapiens OX=9606 GN=TAF15 PE=1 SV=1 5.55 1305.8 - 3.81E+07 - - - -1.1973 - 1.989 0.316 - 372.1 1 2 0 -0.001 9 0 0 0 7.08E+08 6.95E+08 - - - 3.364 0.9979 221125_WJC_METTL3_EV_vs_WT_F07.03542.03542.2 0.0544 20-Jun K.GSSGLGGGSSR.T "sp|Q04695|K1C17_HUMAN,tr|K7EPJ9|K7EPJ9_HUMAN" 2 920.4312 1816.46 92999 3542 2 920.429619 461.2229 "Keratin, type I cytoskeletal 17 OS=Homo sapiens OX=9606 GN=KRT17 PE=1 SV=2" 9.75 1306.7 - 720919 - - - -1.6873 - 1.31 0.332 - 116.3 1 2 0 -0.0016 11 0 0 0 6.98E+09 3.84E+06 - - - 2.2232 0.9984 221125_WJC_METTL3_EV_vs_WT_F07.03543.03543.2 0.0315 18-Jul K.APSGGAVEQK[136.11].V sp|Q14781|CBX2_HUMAN 1 950.4913 4.76 93000 3543 2 950.491238 476.2529 Chromobox protein homolog 2 OS=Homo sapiens OX=9606 GN=CBX2 PE=1 SV=2 6.05 1306.8 - 744199 - - - -0.0231 - 1.258 0.307 - 116.5 1 2 0 0 10 0 0 0 1.58E+08 3.33E+07 - - - 1.9492 0.9917 221125_WJC_METTL3_EV_vs_WT_F07.03544.03544.2 5.01 20-Jun M.PTESASC[160.03]STAR.Q "sp|Q9Y2I8|WDR37_HUMAN,tr|A0A087WTQ2|A0A087WTQ2_HUMAN,tr|E7EQ49|E7EQ49_HUMAN,tr|A0A3B3IT47|A0A3B3IT47_HUMAN" 4 1165.5034 1.27 93001 3544 2 1165.500211 583.759 WD repeat-containing protein 37 OS=Homo sapiens OX=9606 GN=WDR37 PE=1 SV=2 6.39 1306.9 - 185558 - - - -2.6941 - 1.382 0.237 - 56.6 1 2 0 -0.0031 11 0 0 0 2.71E+06 2.14E+06 - - - 1.6657 0.9985 221125_WJC_METTL3_EV_vs_WT_F07.03546.03546.2 0.00184 14-Aug K.FHTVSGSK.C "sp|Q99729|ROAA_HUMAN,tr|D6R9P3|D6R9P3_HUMAN,tr|D6RD18|D6RD18_HUMAN,tr|D6RBZ0|D6RBZ0_HUMAN" 4 861.4345 1.23 93002 3546 2 861.434498 431.7245 Heterogeneous nuclear ribonucleoprotein A\B OS=Homo sapiens OX=9606 GN=HNRNPAB PE=1 SV=2 8.76 1307.1 - 3.64E+06 - - - 0.036 - 1.488 0.242 - 358.1 1 2 0 0 8 0 0 0 2.59E+08 2.11E+08 - - - 2.027 0.9991 221125_WJC_METTL3_EV_vs_WT_F07.03552.03552.2 1.51 14-Aug R.SDAQPPSR.E sp|Q6ZU65|UBN2_HUMAN 1 856.4039 0.3 93006 3552 2 856.402536 429.2092 Ubinuclein-2 OS=Homo sapiens OX=9606 GN=UBN2 PE=1 SV=2 5.55 1307.7 - 3.14E+06 - - - -1.5869 - 1.704 0.314 - 299.8 1 2 0 -0.0014 8 0 0 0 7.07E+07 2.35E+08 - - - 2.9672 0.8476 221125_WJC_METTL3_EV_vs_WT_F07.03554.03554.2 0.169 16-Jul K.LREEQEAAR.R sp|Q8TEK3|DOT1L_HUMAN 1 1100.5574 0.49 93008 3554 2 1100.555823 551.286 "Histone-lysine N-methyltransferase, H3 lysine-79 specific OS=Homo sapiens OX=9606 GN=DOT1L PE=1 SV=3" 4.79 1308 - 221774 - - - -1.4647 - 1.347 0.122 - 71.1 3 2 1 -0.0016 9 0 0 0 4.27E+06 8.76E+06 - - - 0.5902 0.9951 221125_WJC_METTL3_EV_vs_WT_F07.03564.03564.2 0.0165 16-Jun R.STPGPAGSR[166.11].L sp|P57086|SCND1_HUMAN 1 838.4172 0.85 93013 3564 2 838.417436 420.2159 SCAN domain-containing protein 1 OS=Homo sapiens OX=9606 GN=SCAND1 PE=1 SV=1 9.47 1309.2 - 1.56E+06 - - - 0.2218 - 1.427 0.163 - 102 2 2 0 0.0002 9 0 0 0 1.22E+08 1.43E+08 - - - 1.1391 0.999 221125_WJC_METTL3_EV_vs_WT_F07.03567.03567.2 0.0745 16-Sep K.SSTAAQEVK[136.11].T sp|Q9P258|RCC2_HUMAN 1 927.4753 1.03 93014 3567 2 927.474679 464.7449 Protein RCC2 OS=Homo sapiens OX=9606 GN=RCC2 PE=1 SV=2 5.72 1309.6 - 1.91E+06 - - - -0.6426 - 1.761 0.238 - 429 1 2 0 -0.0006 9 0 0 0 5.19E+07 5.05E+07 - - - 2.4358 0.977 221125_WJC_METTL3_EV_vs_WT_F07.03569.03569.2 11.4 14-Aug R.KGANINEK.T sp|Q9H2K2|TNKS2_HUMAN 1 872.4716 8.47 93016 3569 2 872.471351 437.2431 Poly [ADP-ribose] polymerase tankyrase-2 OS=Homo sapiens OX=9606 GN=TNKS2 PE=1 SV=1 8.59 1309.7 - 2.89E+06 - - - -0.2625 - 1.337 0.02 - 280.8 1 2 0 -0.0002 8 0 0 0 1.41E+08 1.67E+07 - - - 0.0646 0.7877 221125_WJC_METTL3_EV_vs_WT_F07.03573.03573.2 1.43 18-May R.TVTGSC[160.03]GPSP.- tr|A0A1W2PS40|A0A1W2PS40_HUMAN 1 961.4175 - 93020 3573 2 961.414372 481.716 "Presenilins-associated rhomboid-like protein, mitochondrial OS=Homo sapiens OX=9606 GN=PARL PE=4 SV=1" 5.18 1310.1 - 652141 - - - -3.2494 - 0.916 0.108 - 61.2 1 2 0 -0.0031 10 0 0 0 - - - - - -0.4072 0.983 221125_WJC_METTL3_EV_vs_WT_F07.03579.03579.2 0.000919 22-Nov L.LEGEGSSGGGGR.G "sp|P13645|K1C10_HUMAN,tr|A0A1B0GVI3|A0A1B0GVI3_HUMAN" 2 1061.4738 155.41 93024 3579 2 1061.475855 531.7442 "Keratin, type I cytoskeletal 10 OS=Homo sapiens OX=9606 GN=KRT10 PE=1 SV=6" 4.53 1310.9 - 5.42E+06 - - - 1.969 - 1.891 0.55 - 356.4 1 1 0 0.0021 12 0 0 0 5.83E+08 3.75E+06 - - - 4.779 0.9996 221125_WJC_METTL3_EV_vs_WT_F07.03580.03580.2 0.0672 12-Jul K.QQSTSYR[166.11].N sp|Q15643|TRIPB_HUMAN 1 878.4122 1.01 93025 3580 2 878.411475 440.2134 Thyroid receptor-interacting protein 11 OS=Homo sapiens OX=9606 GN=TRIP11 PE=1 SV=3 8.75 1310.9 - 3.73E+06 - - - -0.7855 - 1.86 0.336 - 385.7 1 2 0 -0.0007 7 0 0 0 4.73E+08 4.67E+08 - - - 3.4888 0.9314 221125_WJC_METTL3_EV_vs_WT_F07.03581.03581.2 0.00988 14-Jun L.SNNNQALR.R "sp|Q13283|G3BP1_HUMAN,tr|A0A7I2YQB1|A0A7I2YQB1_HUMAN,tr|A0A7I2V5M7|A0A7I2V5M7_HUMAN,tr|E5RH42|E5RH42_HUMAN,tr|A0A7P0P2U7|A0A7P0P2U7_HUMAN,tr|A0A7I2YQU8|A0A7I2YQU8_HUMAN,tr|E5RJU8|E5RJU8_HUMAN,tr|A0A7I2V651|A0A7I2V651_HUMAN,tr|E5RIF8|E5RIF8_HUMAN,tr|A0A7I2YQN9|A0A7I2YQN9_HUMAN,tr|A0A7I2V2V1|A0A7I2V2V1_HUMAN" 11 915.4522 0.87 93026 3581 2 915.453504 458.7334 Ras GTPase-activating protein-binding protein 1 OS=Homo sapiens OX=9606 GN=G3BP1 PE=1 SV=1 9.47 1311 - 3.03E+06 - - - 1.3786 - 1.58 0.297 - 235 1 1 0 0.0013 8 0 0 0 8.17E+07 9.43E+07 - - - 2.6138 0.7632 221125_WJC_METTL3_EV_vs_WT_F07.03583.03583.2 0.175 16-Jun H.TTISGGGSR.G sp|P04264|K2C1_HUMAN 1 834.4195 7 93028 3583 2 834.418818 418.217 "Keratin, type II cytoskeletal 1 OS=Homo sapiens OX=9606 GN=KRT1 PE=1 SV=6" 9.41 1311.1 - 1.98E+06 - - - -0.8713 - 1.233 0.207 - 134.5 1 1 0 -0.0007 9 0 0 0 1.40E+07 2.00E+06 - - - 1.1756 0.9805 221125_WJC_METTL3_EV_vs_WT_F07.03586.03586.2 0.465 14-Jul R.HVANTIC[160.03]K[136.11].A "sp|Q9H8V3|ECT2_HUMAN,tr|H7C103|H7C103_HUMAN" 2 949.4895 0.81 93031 3586 2 949.486501 475.752 Protein ECT2 OS=Homo sapiens OX=9606 GN=ECT2 PE=1 SV=4 8.23 1311.4 - 908228 - - - -3.1438 - 1.388 0.168 - 194.8 1 2 0 -0.003 8 0 0 0 2.41E+07 2.99E+07 - - - 1.2697 0.9997 221125_WJC_METTL3_EV_vs_WT_F07.03597.03597.2 0.000309 18-Oct R.TGAPAQADSR[166.11].G sp|P20290|BTF3_HUMAN 1 982.4707 0.75 93038 3597 2 982.471272 492.2426 Transcription factor BTF3 OS=Homo sapiens OX=9606 GN=BTF3 PE=1 SV=1 5.5 1312.7 - 758360 - - - 0.5395 - 1.706 0.457 - 306.5 1 2 0 0.0005 10 0 0 0 1.34E+08 1.78E+08 - - - 3.9072 0.8999 221125_WJC_METTL3_EV_vs_WT_F07.03601.03601.2 0.624 12-Jun K.VSLKGNR.E "sp|Q9NYF8|BCLF1_HUMAN,tr|E9PKI6|E9PKI6_HUMAN,tr|A0A1W2PQ43|A0A1W2PQ43_HUMAN,tr|E9PK91|E9PK91_HUMAN,tr|E9PK09|E9PK09_HUMAN,tr|E9PQN2|E9PQN2_HUMAN" 6 772.4555 1.59 93040 3601 2 772.453827 387.235 Bcl-2-associated transcription factor 1 OS=Homo sapiens OX=9606 GN=BCLAF1 PE=1 SV=2 11 1313.2 - 3.96E+06 - - - -2.2124 - 1.276 0.198 - 199.1 1 2 1 -0.0017 7 0 0 0 1.04E+08 6.54E+07 - - - 1.2752 0.9989 221125_WJC_METTL3_EV_vs_WT_F07.03603.03603.2 0.011 12-Jun K.QQSTSYR.N sp|Q15643|TRIPB_HUMAN 1 868.4039 1.01 93041 3603 2 868.401502 435.2092 Thyroid receptor-interacting protein 11 OS=Homo sapiens OX=9606 GN=TRIP11 PE=1 SV=3 8.75 1313.4 - 1.67E+07 - - - -2.7556 - 1.416 0.467 - 301.1 1 2 0 -0.0024 7 0 0 0 4.73E+08 4.67E+08 - - - 3.5916 0.9996 221125_WJC_METTL3_EV_vs_WT_F07.03611.03611.2 0.000397 14-Sep K.VPC[160.03]HVC[160.03]GK[136.11].M "sp|P56270|MAZ_HUMAN,tr|H3BQI4|H3BQI4_HUMAN,tr|H3BQS2|H3BQS2_HUMAN,tr|I3L2Z5|I3L2Z5_HUMAN,tr|A0A087WWR2|A0A087WWR2_HUMAN" 5 963.451 1.1 93045 3611 2 963.448859 482.7328 Myc-associated zinc finger protein OS=Homo sapiens OX=9606 GN=MAZ PE=1 SV=1 8.04 1314.4 - 1.85E+06 - - - -2.2139 - 1.743 0.489 - 344.1 1 2 0 -0.0021 8 0 0 0 1.28E+08 1.16E+08 - - - 4.3278 0.9992 221125_WJC_METTL3_EV_vs_WT_F07.03613.03613.2 0.000778 14-Sep K.VPC[160.03]HVC[160.03]GK.M "sp|P56270|MAZ_HUMAN,tr|H3BQI4|H3BQI4_HUMAN,tr|H3BQS2|H3BQS2_HUMAN,tr|I3L2Z5|I3L2Z5_HUMAN,tr|A0A087WWR2|A0A087WWR2_HUMAN" 5 955.4368 1.1 93047 3613 2 955.434226 478.7257 Myc-associated zinc finger protein OS=Homo sapiens OX=9606 GN=MAZ PE=1 SV=1 8.04 1314.5 - 1.85E+06 - - - -2.6857 - 1.631 0.466 - 348.2 1 2 0 -0.0026 8 0 0 0 1.28E+08 1.17E+08 - - - 3.9575 0.8196 221125_WJC_METTL3_EV_vs_WT_F07.03624.03624.2 1.37 14-Jul N.QPEPQEQR.E "sp|O43189|PHF1_HUMAN,tr|A0A140T9U3|A0A140T9U3_HUMAN" 2 1010.4781 1.6 93053 3624 2 1010.476438 506.2463 PHD finger protein 1 OS=Homo sapiens OX=9606 GN=PHF1 PE=1 SV=3 4.53 1315.9 - 2.28E+06 - - - -1.6665 - 1.702 0.149 - 204.8 1 1 0 -0.0017 8 0 0 0 1.04E+08 6.52E+07 - - - 1.7449 0.9693 221125_WJC_METTL3_EV_vs_WT_F07.03627.03627.2 0.887 16-Aug R.VQGETQPQR.L "sp|Q14676|MDC1_HUMAN,tr|A2AB05|A2AB05_HUMAN" 2 1041.5203 1.59 93056 3627 2 1041.522584 521.7674 Mediator of DNA damage checkpoint protein 1 OS=Homo sapiens OX=9606 GN=MDC1 PE=1 SV=3 5.97 1316.2 - 1.25E+06 - - - 2.1718 - 1.144 0.144 - 54.3 1 2 0 0.0023 9 0 0 0 5.26E+07 3.31E+07 - - - 0.4931 0.9998 221125_WJC_METTL3_EV_vs_WT_F07.03630.03630.2 3.39E-06 24-Dec K.AEGGGAEEGAGAR[166.11].G sp|Q10570|CPSF1_HUMAN 1 1140.5035 1.25 93059 3630 2 1140.501687 571.259 Cleavage and polyadenylation specificity factor subunit 1 OS=Homo sapiens OX=9606 GN=CPSF1 PE=1 SV=2 4.25 1316.5 - 223042 - - - -1.5888 - 2.329 0.564 - 559.3 1 2 0 -0.0018 13 0 0 0 5.25E+06 4.20E+06 - - - 5.376 0.8153 221125_WJC_METTL3_EV_vs_WT_F07.03632.03632.2 0.0226 14-Sep G.ENALKDAK.N sp|P04264|K2C1_HUMAN 1 887.4712 175.77 93060 3632 2 887.470044 444.7429 "Keratin, type II cytoskeletal 1 OS=Homo sapiens OX=9606 GN=KRT1 PE=1 SV=6" 6.17 1316.7 - 1.88E+07 - - - -1.3544 - 1.865 0.399 - 398.1 1 1 1 -0.0012 8 0 0 0 5.21E+08 2.96E+06 - - - 3.8674 0.9998 221125_WJC_METTL3_EV_vs_WT_F07.03634.03634.2 0.00464 18-Sep R.TGAPAQADSR.G sp|P20290|BTF3_HUMAN 1 972.4625 0.65 93061 3634 2 972.461999 487.2385 Transcription factor BTF3 OS=Homo sapiens OX=9606 GN=BTF3 PE=1 SV=1 5.5 1316.9 - 5.88E+06 - - - -0.4864 - 1.882 0.434 - 368.6 1 2 0 -0.0005 10 0 0 0 1.35E+08 2.05E+08 - - - 4.0114 0.999 221125_WJC_METTL3_EV_vs_WT_F07.03635.03635.2 0.0998 16-Dec K.TQARPVGVK.L "sp|O95433|AHSA1_HUMAN,tr|G3V438|G3V438_HUMAN,tr|H0YJG7|H0YJG7_HUMAN" 3 954.5611 1.8 93062 3635 2 954.559149 478.2878 Activator of 90 kDa heat shock protein ATPase homolog 1 OS=Homo sapiens OX=9606 GN=AHSA1 PE=1 SV=1 11 1317 - 4.35E+06 - - - -2.0062 - 2.043 0.276 - 551.9 1 2 0 -0.0019 9 0 0 0 9.58E+07 5.31E+07 - - - 3.1458 0.9998 221125_WJC_METTL3_EV_vs_WT_F07.03639.03639.2 4.51E-06 24-Sep K.AEGGGAEEGAGAR.G sp|Q10570|CPSF1_HUMAN 1 1130.4952 1.25 93064 3639 2 1130.493081 566.2549 Cleavage and polyadenylation specificity factor subunit 1 OS=Homo sapiens OX=9606 GN=CPSF1 PE=1 SV=2 4.25 1317.5 - 481732 - - - -1.9001 - 2.065 0.533 - 259.2 1 2 0 -0.0021 13 0 0 0 5.25E+06 4.20E+06 - - - 4.8381 0.9996 221125_WJC_METTL3_EV_vs_WT_F07.03643.03643.2 0.00353 16-Sep R.VQGETQPQR[166.11].L "sp|Q14676|MDC1_HUMAN,tr|A2AB05|A2AB05_HUMAN" 2 1051.5286 1.61 93067 3643 2 1051.527438 526.7716 Mediator of DNA damage checkpoint protein 1 OS=Homo sapiens OX=9606 GN=MDC1 PE=1 SV=3 5.97 1317.9 - 1.92E+06 - - - -1.0974 - 1.501 0.465 - 343.2 1 2 0 -0.0012 9 0 0 0 5.40E+07 3.35E+07 - - - 3.6501 0.9993 221125_WJC_METTL3_EV_vs_WT_F07.03645.03645.2 0.0406 14-Oct K.KLQGEVEK.Y "sp|O15212|PFD6_HUMAN,tr|A2AB88|A2AB88_HUMAN" 2 929.5182 4.06 93068 3645 2 929.516822 465.7664 Prefoldin subunit 6 OS=Homo sapiens OX=9606 GN=PFDN6 PE=1 SV=1 6.14 1318.1 - 2.97E+06 - - - -1.4782 - 2.063 0.263 - 354.8 1 2 0 -0.0014 8 0 0 0 2.23E+08 5.49E+07 - - - 3.1671 0.9905 221125_WJC_METTL3_EV_vs_WT_F07.03647.03647.2 6.59E-05 18-Nov L.AGQVAAANK[136.11]K[136.11].H "sp|P39019|RS19_HUMAN,tr|A0A075B6E2|A0A075B6E2_HUMAN" 2 972.5687 1.23 93070 3647 2 972.567752 487.2916 40S ribosomal protein S19 OS=Homo sapiens OX=9606 GN=RPS19 PE=1 SV=2 10 1318.2 - 7.79E+06 - - - -1.0046 - 2.092 0.486 - 545.4 1 1 0 -0.001 10 0 0 0 4.56E+08 3.70E+08 - - - 4.6906 0.8152 221125_WJC_METTL3_EV_vs_WT_F07.03657.03657.2 0.000541 12-Jul V.PC[160.03]HVC[160.03]GK[136.11].M "sp|P56270|MAZ_HUMAN,tr|H3BQI4|H3BQI4_HUMAN,tr|H3BQS2|H3BQS2_HUMAN,tr|I3L2Z5|I3L2Z5_HUMAN,tr|A0A087WWR2|A0A087WWR2_HUMAN" 5 864.3826 0.99 93076 3657 2 864.381604 433.1986 Myc-associated zinc finger protein OS=Homo sapiens OX=9606 GN=MAZ PE=1 SV=1 8.44 1319.4 - 5.46E+06 - - - -1.1268 - 1.412 0.183 - 222.7 1 1 0 -0.001 7 0 0 0 2.33E+08 2.35E+08 - - - 1.4855 0.9932 221125_WJC_METTL3_EV_vs_WT_F07.03661.03661.2 0.224 14-Sep R.R[166.11]LEAEQAR[166.11].E "sp|Q14244|MAP7_HUMAN,tr|A0A087WZ40|A0A087WZ40_HUMAN" 2 991.5314 1.24 93078 3661 2 991.529364 496.773 Ensconsin OS=Homo sapiens OX=9606 GN=MAP7 PE=1 SV=1 6.14 1319.9 - 1.21E+06 - - - -2.0352 - 1.376 0.197 - 184.6 1 2 0 -0.002 8 0 0 0 7.30E+07 5.91E+07 - - - 1.458 0.9645 221125_WJC_METTL3_EV_vs_WT_F07.03665.03665.2 0.023 14-Jul R.GTFADKEK.K sp|P08579|RU2B_HUMAN 1 894.4447 0.88 93080 3665 2 894.442115 448.2296 U2 small nuclear ribonucleoprotein B'' OS=Homo sapiens OX=9606 GN=SNRPB2 PE=1 SV=1 6.07 1320.4 - 4.36E+06 - - - -2.8867 - 1.383 0.346 - 194.2 1 2 1 -0.0026 8 0 0 0 8.49E+07 9.67E+07 - - - 2.5737 0.9981 221125_WJC_METTL3_EV_vs_WT_F07.03667.03667.2 0.232 16-Sep R.QTQVNEATK[136.11].A "sp|Q8WWY3|PRP31_HUMAN,tr|E7EVX8|E7EVX8_HUMAN" 2 1025.5233 2.57 93082 3667 2 1025.523216 513.7689 U4\U6 small nuclear ribonucleoprotein Prp31 OS=Homo sapiens OX=9606 GN=PRPF31 PE=1 SV=2 6 1320.6 - 699435 - - - -0.0702 - 1.605 0.192 - 373.2 1 2 0 -0.0001 9 0 0 0 1.15E+09 4.46E+08 - - - 1.8279 0.9593 221125_WJC_METTL3_EV_vs_WT_F07.03679.03679.2 0.951 16-Sep A.GQVAAANKK.H "sp|P39019|RS19_HUMAN,tr|A0A075B6E2|A0A075B6E2_HUMAN" 2 885.5032 1.25 93088 3679 2 885.50218 443.7589 40S ribosomal protein S19 OS=Homo sapiens OX=9606 GN=RPS19 PE=1 SV=2 10 1322 - 9.21E+06 - - - -1.1688 - 1.963 0.263 - 316.9 1 1 0 -0.001 9 0 0 0 1.80E+08 1.43E+08 - - - 2.9345 0.9998 221125_WJC_METTL3_EV_vs_WT_F07.03687.03687.2 6.54E-05 20-Dec R.IAGQVAAANK[136.11]K[136.11].H "sp|P39019|RS19_HUMAN,tr|A0A075B6E2|A0A075B6E2_HUMAN" 2 1085.6528 1.15 93095 3687 2 1085.651211 543.8337 40S ribosomal protein S19 OS=Homo sapiens OX=9606 GN=RPS19 PE=1 SV=2 10 1322.8 - 2.59E+07 - - - -1.4572 - 2.501 0.482 - 488.4 1 2 0 -0.0016 11 0 0 0 1.17E+09 1.02E+09 - - - 5.0804 0.8117 221125_WJC_METTL3_EV_vs_WT_F07.03688.03688.2 0.000202 12-Jul V.PC[160.03]HVC[160.03]GK.M "sp|P56270|MAZ_HUMAN,tr|H3BQI4|H3BQI4_HUMAN,tr|H3BQS2|H3BQS2_HUMAN,tr|I3L2Z5|I3L2Z5_HUMAN,tr|A0A087WWR2|A0A087WWR2_HUMAN" 5 856.3684 0.97 93096 3688 2 856.36773 429.1915 Myc-associated zinc finger protein OS=Homo sapiens OX=9606 GN=MAZ PE=1 SV=1 8.44 1322.9 - 3.17E+06 - - - -0.7567 - 1.521 0.134 - 225.6 1 1 0 -0.0006 7 0 0 0 2.34E+08 2.40E+08 - - - 1.3593 0.8636 221125_WJC_METTL3_EV_vs_WT_F07.03690.03690.2 2.11 12-Apr R.NFQTAHR.R "sp|O75475|PSIP1_HUMAN,tr|V9GYT7|V9GYT7_HUMAN" 2 872.4253 0.66 93098 3690 2 872.423789 437.2199 PC4 and SFRS1-interacting protein OS=Homo sapiens OX=9606 GN=PSIP1 PE=1 SV=1 9.76 1323 - 2.50E+06 - - - -1.7308 - 0.872 0.129 - 57.7 5 2 0 -0.0015 7 0 0 0 3.30E+07 5.01E+07 - - - -0.7529 0.9989 221125_WJC_METTL3_EV_vs_WT_F07.03696.03696.2 0.0253 14-Jul K.ISQETEQR.C "sp|P52732|KIF11_HUMAN,tr|A0A7I2V3A9|A0A7I2V3A9_HUMAN" 2 989.4778 4.33 93102 3696 2 989.476247 495.7462 Kinesin-like protein KIF11 OS=Homo sapiens OX=9606 GN=KIF11 PE=1 SV=2 4.53 1323.6 - 4.32E+06 - - - -1.5574 - 1.708 0.284 - 184.4 1 2 0 -0.0015 8 0 0 0 2.36E+09 5.45E+08 - - - 2.7526 0.9991 221125_WJC_METTL3_EV_vs_WT_F07.03698.03698.2 0.0126 14-Jun K.VEALHQNR.E sp|Q9UL40|ZN346_HUMAN 1 965.5043 0.71 93104 3698 2 965.50281 483.7594 Zinc finger protein 346 OS=Homo sapiens OX=9606 GN=ZNF346 PE=1 SV=1 6.72 1323.7 - 1.94E+06 - - - -1.5204 - 1.546 0.347 - 180.9 1 2 0 -0.0015 8 0 0 0 3.57E+07 5.04E+07 - - - 2.9174 0.9994 221125_WJC_METTL3_EV_vs_WT_F07.03702.03702.2 0.0509 14-Aug K.ISQETEQR[166.11].C "sp|P52732|KIF11_HUMAN,tr|A0A7I2V3A9|A0A7I2V3A9_HUMAN" 2 999.4861 4.34 93106 3702 2 999.485443 500.7503 Kinesin-like protein KIF11 OS=Homo sapiens OX=9606 GN=KIF11 PE=1 SV=2 4.53 1324.2 - 4.72E+06 - - - -0.6153 - 1.825 0.28 - 234.6 1 2 0 -0.0006 8 0 0 0 2.36E+09 5.45E+08 - - - 2.9232 0.9854 221125_WJC_METTL3_EV_vs_WT_F07.03707.03707.2 0.0358 12-Jul R.MKVEQER.K "sp|P82094|TMF1_HUMAN,tr|A0A2R8Y7M0|A0A2R8Y7M0_HUMAN" 2 918.4593 1.13 93109 3707 2 918.459211 460.2369 TATA element modulatory factor OS=Homo sapiens OX=9606 GN=TMF1 PE=1 SV=2 5.9 1324.7 - 2.87E+06 - - - -0.098 - 1.623 0.21 - 166.5 1 2 1 -0.0001 7 0 0 0 4.61E+07 4.07E+07 - - - 2.1265 0.9712 221125_WJC_METTL3_EV_vs_WT_F07.03710.03710.2 0.291 14-Jul R.QTLGREPK.S sp|Q14681|KCTD2_HUMAN 1 927.5138 4.33 93111 3710 2 927.51348 464.7642 BTB\POZ domain-containing protein KCTD2 OS=Homo sapiens OX=9606 GN=KCTD2 PE=1 SV=3 8.75 1325 - 4.00E+06 - - - -0.3234 - 1.417 0.201 - 240.9 1 2 1 -0.0003 8 0 0 0 2.12E+08 4.89E+07 - - - 1.5767 0.9995 221125_WJC_METTL3_EV_vs_WT_F07.03717.03717.2 0.00797 16-Sep K.TESASVQGR.N "sp|Q9P2E9|RRBP1_HUMAN,tr|A0A087WVV2|A0A087WVV2_HUMAN,tr|V9GY78|V9GY78_HUMAN" 3 933.4516 1.07 93116 3717 2 933.450502 467.7331 Ribosome-binding protein 1 OS=Homo sapiens OX=9606 GN=RRBP1 PE=1 SV=5 5.66 1325.7 - 2.56E+06 - - - -1.1474 - 1.879 0.335 - 362.3 1 2 0 -0.0011 9 0 0 0 1.13E+08 1.06E+08 - - - 3.3397 0.9954 221125_WJC_METTL3_EV_vs_WT_F07.03720.03720.2 0.0487 14-Jun K.AYEKPPEK.K "sp|Q12905|ILF2_HUMAN,tr|B4DY09|B4DY09_HUMAN" 2 960.4916 2.84 93118 3720 2 960.493085 481.2531 Interleukin enhancer-binding factor 2 OS=Homo sapiens OX=9606 GN=ILF2 PE=1 SV=2 6.19 1326 - 2.71E+06 - - - 1.4971 - 1.171 0.277 - 152.2 1 2 0 0.0014 8 0 0 0 1.30E+08 4.59E+07 - - - 1.5626 0.9991 221125_WJC_METTL3_EV_vs_WT_F07.03731.03731.2 0.0886 14-Sep K.KAAEVLNK.H "sp|P52272|HNRPM_HUMAN,tr|M0R019|M0R019_HUMAN,tr|M0R0N3|M0R0N3_HUMAN,tr|A0A087X0X3|A0A087X0X3_HUMAN,tr|M0QYQ7|M0QYQ7_HUMAN,tr|M0R2T0|M0R2T0_HUMAN" 6 871.5127 1.64 93124 3731 2 871.511428 436.7636 Heterogeneous nuclear ribonucleoprotein M OS=Homo sapiens OX=9606 GN=HNRNPM PE=1 SV=3 8.59 1327.3 - 9.45E+06 - - - -1.479 - 1.717 0.293 - 268.2 1 2 0 -0.0013 8 0 0 0 7.62E+08 4.64E+08 - - - 2.8351 0.9996 221125_WJC_METTL3_EV_vs_WT_F07.03732.03732.2 0.0244 16-Oct K.TESASVQGR[166.11].N "sp|Q9P2E9|RRBP1_HUMAN,tr|A0A087WVV2|A0A087WVV2_HUMAN,tr|V9GY78|V9GY78_HUMAN" 3 943.4598 1.07 93125 3732 2 943.457951 472.7372 Ribosome-binding protein 1 OS=Homo sapiens OX=9606 GN=RRBP1 PE=1 SV=5 5.66 1327.4 - 6.51E+06 - - - -2.0054 - 2.018 0.422 - 470.9 1 2 0 -0.0019 9 0 0 0 1.13E+08 1.06E+08 - - - 4.1885 0.9827 221125_WJC_METTL3_EV_vs_WT_F07.03742.03742.2 1.14 12-Jun R.VTLTNHK[136.11].K "sp|O43660|PLRG1_HUMAN,tr|H0YAA2|H0YAA2_HUMAN,tr|H0YA24|H0YA24_HUMAN" 3 819.4694 1.15 93130 3742 2 819.468472 410.742 Pleiotropic regulator 1 OS=Homo sapiens OX=9606 GN=PLRG1 PE=1 SV=1 8.73 1328.6 - 1.33E+06 - - - -1.1349 - 1.271 0.101 - 114 2 2 0 -0.0009 7 0 0 0 4.52E+07 3.94E+07 - - - 0.4121 0.9108 221125_WJC_METTL3_EV_vs_WT_F07.03744.03744.2 0.0714 16-Jun F.VVC[160.03]NEC[160.03]GNR[166.11].W "sp|P23193|TCEA1_HUMAN,sp|Q15560|TCEA2_HUMAN,tr|B7Z4S1|B7Z4S1_HUMAN,tr|A0A0A0MT58|A0A0A0MT58_HUMAN,tr|A0A1W2PRL9|A0A1W2PRL9_HUMAN,tr|A0A1W2PPZ5|A0A1W2PPZ5_HUMAN" 6 1116.468 0.63 93132 3744 2 1116.465416 559.2413 Transcription elongation factor A protein 1 OS=Homo sapiens OX=9606 GN=TCEA1 PE=1 SV=2 5.96 1328.8 - 252507 - - - -2.2983 - 1.443 0.369 - 128.5 1 1 0 -0.0026 9 0 0 0 2.57E+06 4.09E+06 - - - 2.8266 0.9995 221125_WJC_METTL3_EV_vs_WT_F07.03746.03746.2 0.00236 16-Aug R.QTQVNEATK.A "sp|Q8WWY3|PRP31_HUMAN,tr|E7EVX8|E7EVX8_HUMAN" 2 1017.5091 2.57 93133 3746 2 1017.507643 509.7618 U4\U6 small nuclear ribonucleoprotein Prp31 OS=Homo sapiens OX=9606 GN=PRPF31 PE=1 SV=2 6 1329 - 6.45E+06 - - - -1.4201 - 1.601 0.424 - 212.7 1 2 0 -0.0014 9 0 0 0 1.15E+09 4.46E+08 - - - 3.5338 0.9995 221125_WJC_METTL3_EV_vs_WT_F07.03748.03748.2 0.0184 12-Aug R.HAYPDGR[166.11].L "sp|Q9H000|MKRN2_HUMAN,sp|Q9UHC7|MKRN1_HUMAN,tr|A0A7I2V5D2|A0A7I2V5D2_HUMAN,tr|A0A7I2YQI0|A0A7I2YQI0_HUMAN,tr|C9J494|C9J494_HUMAN" 5 824.3805 0.98 93134 3748 2 824.380077 413.1975 Probable E3 ubiquitin-protein ligase makorin-2 OS=Homo sapiens OX=9606 GN=MKRN2 PE=1 SV=2 6.74 1329.2 - 1.84E+06 - - - -0.4779 - 1.524 0.351 - 269.9 1 2 0 -0.0004 7 0 0 0 3.98E+07 4.07E+07 - - - 2.9684 0.7951 221125_WJC_METTL3_EV_vs_WT_F07.03754.03754.2 0.7 20-Jun R.ALYLAVYDLSK[136.11].G "sp|Q5S007|LRRK2_HUMAN,tr|A0A7P0T8S1|A0A7P0T8S1_HUMAN" 2 1262.7002 0.001 93140 3754 2 1262.705237 632.3574 Leucine-rich repeat serine\threonine-protein kinase 2 OS=Homo sapiens OX=9606 GN=LRRK2 PE=1 SV=2 5.88 1329.8 - 174019 - - - 3.997 - 1.344 0.019 - 80.9 1 2 0 0.005 11 0 0 0 0.00E+00 3.91E+06 - - - -0.0204 0.9987 221125_WJC_METTL3_EV_vs_WT_F07.03757.03757.2 0.779 18-Sep R.GGSDGYGSGR[166.11].G "sp|P22626|ROA2_HUMAN,tr|A0A024RA28|A0A024RA28_HUMAN,tr|A0A7I2V4N1|A0A7I2V4N1_HUMAN,tr|A0A7I2V4S4|A0A7I2V4S4_HUMAN,tr|A0A7I2V323|A0A7I2V323_HUMAN,tr|A0A7I2V3P1|A0A7I2V3P1_HUMAN,tr|A0A7I2V3P7|A0A7I2V3P7_HUMAN" 7 921.3816 1.24 93141 3757 2 921.379598 461.6981 Heterogeneous nuclear ribonucleoproteins A2\B1 OS=Homo sapiens OX=9606 GN=HNRNPA2B1 PE=1 SV=2 5.84 1330.2 - 1.47E+06 - - - -2.1652 - 1.65 0.342 - 390.8 1 2 0 -0.002 10 0 0 0 2.25E+07 1.81E+07 - - - 2.9642 0.9984 221125_WJC_METTL3_EV_vs_WT_F07.03762.03762.2 0.133 14-Nov K.K[136.11]EQLADAR[166.11].R "sp|P11387|TOP1_HUMAN,tr|A0A7P0T852|A0A7P0T852_HUMAN" 2 947.5155 0.78 93144 3762 2 947.514262 474.765 DNA topoisomerase 1 OS=Homo sapiens OX=9606 GN=TOP1 PE=1 SV=2 6.07 1330.9 - 2.45E+06 - - - -1.3214 - 1.886 0.174 - 547.4 1 2 0 -0.0013 8 0 0 0 2.63E+07 3.37E+07 - - - 2.2393 0.9996 221125_WJC_METTL3_EV_vs_WT_F07.03763.03763.2 1.42E-05 18-Sep R.GGSDGYGSGR.G "sp|P22626|ROA2_HUMAN,tr|A0A024RA28|A0A024RA28_HUMAN,tr|A0A7I2V4N1|A0A7I2V4N1_HUMAN,tr|A0A7I2V4S4|A0A7I2V4S4_HUMAN,tr|A0A7I2V323|A0A7I2V323_HUMAN,tr|A0A7I2V3P1|A0A7I2V3P1_HUMAN,tr|A0A7I2V3P7|A0A7I2V3P7_HUMAN" 7 911.3733 1.24 93145 3763 2 911.372087 456.6939 Heterogeneous nuclear ribonucleoproteins A2\B1 OS=Homo sapiens OX=9606 GN=HNRNPA2B1 PE=1 SV=2 5.84 1330.9 - 1.54E+06 - - - -1.3562 - 1.796 0.396 - 342 1 2 0 -0.0012 10 0 0 0 2.25E+07 1.82E+07 - - - 3.5999 0.9721 221125_WJC_METTL3_EV_vs_WT_F07.03765.03765.2 1.15 14-Jun R.ALHVNNDR.A sp|Q6P2Q9|PRP8_HUMAN 1 937.473 1.72 93147 3765 2 937.474321 469.7438 Pre-mRNA-processing-splicing factor 8 OS=Homo sapiens OX=9606 GN=PRPF8 PE=1 SV=2 6.79 1331.1 - 1.22E+06 - - - 1.4336 - 1.32 0.081 - 118.6 3 2 0 0.0013 8 0 0 0 2.78E+07 1.62E+07 - - - 0.263 0.9977 221125_WJC_METTL3_EV_vs_WT_F07.03769.03769.2 0.601 16-Sep K.KIQNDAGVR.L "sp|Q96I24|FUBP3_HUMAN,sp|Q92945|FUBP2_HUMAN,sp|Q96AE4|FUBP1_HUMAN,tr|M0R0I5|M0R0I5_HUMAN,tr|E9PEB5|E9PEB5_HUMAN,tr|M0R0C6|M0R0C6_HUMAN,tr|A0A087WTP3|A0A087WTP3_HUMAN" 7 999.5461 1.77 93149 3769 2 999.544642 500.7803 Far upstream element-binding protein 3 OS=Homo sapiens OX=9606 GN=FUBP3 PE=1 SV=2 8.75 1331.6 - 6.62E+06 - - - -1.5007 - 1.607 0.221 - 336.5 1 2 0 -0.0015 9 0 0 0 2.89E+08 1.63E+08 - - - 2.0452 0.9976 221125_WJC_METTL3_EV_vs_WT_F07.03771.03771.2 0.353 16-Aug K.K[136.11]IQNDAGVR[166.11].L "sp|Q96I24|FUBP3_HUMAN,sp|Q92945|FUBP2_HUMAN,sp|Q96AE4|FUBP1_HUMAN,tr|M0R0I5|M0R0I5_HUMAN,tr|E9PEB5|E9PEB5_HUMAN,tr|M0R0C6|M0R0C6_HUMAN,tr|A0A087WTP3|A0A087WTP3_HUMAN" 7 1017.5686 1.77 93151 3771 2 1017.5672 509.7916 Far upstream element-binding protein 3 OS=Homo sapiens OX=9606 GN=FUBP3 PE=1 SV=2 8.75 1331.7 - 4.79E+06 - - - -1.3876 - 1.631 0.201 - 258.6 1 2 0 -0.0014 9 0 0 0 2.89E+08 1.63E+08 - - - 1.9404 0.9998 221125_WJC_METTL3_EV_vs_WT_F07.03776.03776.2 0.00384 16-Oct R.TSQETADVK.A "sp|Q8N1F7|NUP93_HUMAN,tr|H3BM93|H3BM93_HUMAN,tr|H3BV11|H3BV11_HUMAN,tr|H3BRI8|H3BRI8_HUMAN,tr|H3BNN5|H3BNN5_HUMAN,tr|H3BVG0|H3BVG0_HUMAN" 6 977.4666 2.18 93154 3776 2 977.465206 489.7406 Nuclear pore complex protein Nup93 OS=Homo sapiens OX=9606 GN=NUP93 PE=1 SV=2 4.37 1332.3 - 1.07E+07 - - - -1.3801 - 2.056 0.479 - 480.5 1 2 0 -0.0013 9 0 0 0 2.22E+08 1.01E+08 - - - 4.6637 0.9973 221125_WJC_METTL3_EV_vs_WT_F07.03777.03777.2 0.127 12-Jul R.QSNETYR[166.11].D "sp|P78332|RBM6_HUMAN,tr|C9J250|C9J250_HUMAN,tr|E9PGM9|E9PGM9_HUMAN" 3 906.4071 1.31 93155 3777 2 906.405475 454.2108 RNA-binding protein 6 OS=Homo sapiens OX=9606 GN=RBM6 PE=1 SV=5 6 1332.4 - 1.32E+06 - - - -1.7696 - 1.361 0.275 - 231.4 1 2 0 -0.0016 7 0 0 0 1.87E+07 1.43E+07 - - - 2.0483 0.9672 221125_WJC_METTL3_EV_vs_WT_F07.03778.03778.2 0.686 12-Jun K.TQLSQGR[166.11].S sp|Q8ND56|LS14A_HUMAN 1 798.4223 0.41 93156 3778 2 798.421234 400.2184 Protein LSM14 homolog A OS=Homo sapiens OX=9606 GN=LSM14A PE=1 SV=3 9.41 1332.5 - 8.24E+06 - - - -1.3802 - 1.156 0.077 - 224.8 1 2 0 -0.0011 7 0 0 0 7.47E+07 1.83E+08 - - - 0.0687 0.9928 221125_WJC_METTL3_EV_vs_WT_F07.03779.03779.2 0.632 12-Jul K.AEDEVQR[166.11].E "sp|P0DMV8|HS71A_HUMAN,sp|P34931|HS71L_HUMAN,sp|P0DMV9|HS71B_HUMAN,tr|Q53FA3|Q53FA3_HUMAN,tr|V9GZ37|V9GZ37_HUMAN,tr|A0A0G2JIW1|A0A0G2JIW1_HUMAN" 6 855.3962 0.14 93157 3779 2 855.393732 428.7054 Heat shock 70 kDa protein 1A OS=Homo sapiens OX=9606 GN=HSPA1A PE=1 SV=1 4.14 1332.6 - 1.08E+06 - - - -2.8618 - 1.517 0.206 - 276.8 1 2 0 -0.0024 7 0 0 0 3.15E+06 2.24E+07 - - - 1.8822 0.9992 221125_WJC_METTL3_EV_vs_WT_F07.03780.03780.2 10.3 14-Sep R.LEQEEQQR[166.11].L "sp|Q3ZCQ8|TIM50_HUMAN,tr|M0R0C3|M0R0C3_HUMAN,tr|M0R2F8|M0R2F8_HUMAN" 3 1068.5075 1.05 93158 3780 2 1068.506466 535.261 Mitochondrial import inner membrane translocase subunit TIM50 OS=Homo sapiens OX=9606 GN=TIMM50 PE=1 SV=2 4.25 1332.7 - 767918 - - - -0.9883 - 1.784 0.26 - 322.5 1 2 0 -0.0011 8 0 0 0 1.99E+07 1.89E+07 - - - 2.7068 0.9899 221125_WJC_METTL3_EV_vs_WT_F07.03781.03781.2 1.59 14-Jun R.AHPPEDPR.L "sp|Q92785|REQU_HUMAN,tr|J3KMZ8|J3KMZ8_HUMAN,tr|E9PN04|E9PN04_HUMAN" 3 917.4355 0.68 93159 3781 2 917.436283 459.725 Zinc finger protein ubi-d4 OS=Homo sapiens OX=9606 GN=DPF2 PE=1 SV=2 5.32 1332.8 - 635736 - - - 0.8219 - 1.186 0.162 - 145.4 1 2 0 0.0008 8 0 0 0 1.51E+07 2.24E+07 - - - 0.7518 0.9984 221125_WJC_METTL3_EV_vs_WT_F07.03782.03782.2 0.00115 18-Nov K.QAEVANQETK.E "sp|P05114|HMGN1_HUMAN,tr|A6NEL0|A6NEL0_HUMAN,tr|A6NL93|A6NL93_HUMAN" 3 1116.5411 0.86 93160 3782 2 1116.538088 559.2778 Non-histone chromosomal protein HMG-14 OS=Homo sapiens OX=9606 GN=HMGN1 PE=1 SV=3 4.53 1332.9 - 492545 - - - -2.7128 - 2.042 0.287 - 447.7 1 2 0 -0.003 10 0 0 0 8.13E+07 9.42E+07 - - - 3.1526 0.9892 221125_WJC_METTL3_EV_vs_WT_F07.03789.03789.2 0.197 14-May K.KFGNPGEK.L "sp|P17844|DDX5_HUMAN,tr|J3QR02|J3QR02_HUMAN,tr|J3QKN9|J3QKN9_HUMAN,tr|X6RLV5|X6RLV5_HUMAN,tr|A0A7I2V507|A0A7I2V507_HUMAN,tr|J3KTA4|J3KTA4_HUMAN,tr|J3KTQ4|J3KTQ4_HUMAN,tr|A0A7I2V2S0|A0A7I2V2S0_HUMAN,tr|J3QRQ7|J3QRQ7_HUMAN" 9 875.4501 1.4 93164 3789 2 875.448329 438.7323 Probable ATP-dependent RNA helicase DDX5 OS=Homo sapiens OX=9606 GN=DDX5 PE=1 SV=1 8.59 1333.7 - 3.69E+06 - - - -2.0424 - 1.159 0.221 - 84.5 1 2 0 -0.0018 8 0 0 0 3.09E+08 2.21E+08 - - - 1.1178 0.9998 221125_WJC_METTL3_EV_vs_WT_F07.03795.03795.2 5.07E-05 16-Sep K.MTTEEQQQR[166.11].H sp|Q8IU81|I2BP1_HUMAN 1 1159.5167 1.19 93168 3795 2 1159.515419 580.7656 Interferon regulatory factor 2-binding protein 1 OS=Homo sapiens OX=9606 GN=IRF2BP1 PE=1 SV=1 4.53 1334.4 - 1.11E+06 - - - -1.1099 - 2.012 0.463 - 450.1 1 2 0 -0.0013 9 0 0 0 7.17E+07 6.01E+07 - - - 4.4829 0.9998 221125_WJC_METTL3_EV_vs_WT_F07.03796.03796.2 0.00012 16-Sep K.MTTEEQQQR.H sp|Q8IU81|I2BP1_HUMAN 1 1149.5084 1.19 93169 3796 2 1149.506678 575.7615 Interferon regulatory factor 2-binding protein 1 OS=Homo sapiens OX=9606 GN=IRF2BP1 PE=1 SV=1 4.53 1334.6 - 1.38E+06 - - - -1.5293 - 2.06 0.517 - 476.7 1 2 0 -0.0018 9 0 0 0 7.17E+07 6.01E+07 - - - 4.9498 0.9984 221125_WJC_METTL3_EV_vs_WT_F07.03803.03803.2 2.22 14-Aug R.LEQEEQQR.L "sp|Q3ZCQ8|TIM50_HUMAN,tr|M0R0C3|M0R0C3_HUMAN,tr|M0R2F8|M0R2F8_HUMAN" 3 1058.4993 1.05 93174 3803 2 1058.497839 530.2569 Mitochondrial import inner membrane translocase subunit TIM50 OS=Homo sapiens OX=9606 GN=TIMM50 PE=1 SV=2 4.25 1335.5 - 1.87E+06 - - - -1.3349 - 1.715 0.217 - 327.3 1 2 0 -0.0014 8 0 0 0 1.99E+07 1.89E+07 - - - 2.2702 0.9995 221125_WJC_METTL3_EV_vs_WT_F07.03810.03810.2 0.00512 14-Aug R.LSAK[136.11]PPAK[136.11].V "sp|P05114|HMGN1_HUMAN,tr|F2Z2W6|F2Z2W6_HUMAN,tr|F2Z2Y5|F2Z2Y5_HUMAN,tr|A6NEL0|A6NEL0_HUMAN,tr|H7BXJ5|H7BXJ5_HUMAN,tr|A0A494C035|A0A494C035_HUMAN" 6 826.5247 0.82 93179 3810 2 826.524302 414.2696 Non-histone chromosomal protein HMG-14 OS=Homo sapiens OX=9606 GN=HMGN1 PE=1 SV=3 10 1336.2 - 530304 - - - -0.5287 - 1.596 0.344 - 189.6 1 2 0 -0.0004 8 0 0 0 1.52E+08 1.86E+08 - - - 2.9916 0.9986 221125_WJC_METTL3_EV_vs_WT_F07.03814.03814.2 0.0737 14-Aug K.FVEEQHTK.K sp|Q96A49|SYAP1_HUMAN 1 1016.4927 1.24 93181 3814 2 1016.49246 509.2536 Synapse-associated protein 1 OS=Homo sapiens OX=9606 GN=SYAP1 PE=1 SV=1 5.4 1336.7 - 8.33E+06 - - - -0.2459 - 1.34 0.293 - 158.7 1 2 0 -0.0003 8 0 0 0 1.17E+09 9.47E+08 - - - 2.0877 0.9993 221125_WJC_METTL3_EV_vs_WT_F07.03816.03816.2 0.0898 12-Oct K.HAEELER.L sp|Q9UHB9|SRP68_HUMAN 1 882.4195 0.89 93183 3816 2 882.418208 442.217 Signal recognition particle subunit SRP68 OS=Homo sapiens OX=9606 GN=SRP68 PE=1 SV=2 4.75 1336.8 - 4.42E+06 - - - -1.5152 - 1.855 0.283 - 342.3 1 2 0 -0.0013 7 0 0 0 7.32E+07 8.25E+07 - - - 3.0886 0.9987 221125_WJC_METTL3_EV_vs_WT_F07.03823.03823.2 0.0213 12-Aug K.HAEELER[166.11].L sp|Q9UHB9|SRP68_HUMAN 1 892.4278 0.89 93188 3823 2 892.426556 447.2212 Signal recognition particle subunit SRP68 OS=Homo sapiens OX=9606 GN=SRP68 PE=1 SV=2 4.75 1337.6 - 6.59E+06 - - - -1.4108 - 1.532 0.28 - 211.2 1 2 0 -0.0013 7 0 0 0 7.30E+07 8.25E+07 - - - 2.4603 0.9955 221125_WJC_METTL3_EV_vs_WT_F07.03824.03824.2 0.563 14-Sep R.KGPEALGK.V sp|O00443|P3C2A_HUMAN 1 798.46 1.34 93189 3824 2 798.458111 400.2373 Phosphatidylinositol 4-phosphate 3-kinase C2 domain-containing subunit alpha OS=Homo sapiens OX=9606 GN=PIK3C2A PE=1 SV=2 8.59 1337.7 - 1.45E+06 - - - -2.3069 - 1.775 0.157 - 274 1 2 0 -0.0018 8 0 0 0 3.44E+07 2.56E+07 - - - 1.9306 0.9997 221125_WJC_METTL3_EV_vs_WT_F07.03825.03825.2 0.00363 16-Aug R.NETETAEER.V sp|Q14789|GOGB1_HUMAN 1 1077.4574 1.79 93190 3825 2 1077.457772 539.736 Golgin subfamily B member 1 OS=Homo sapiens OX=9606 GN=GOLGB1 PE=1 SV=2 4.09 1337.8 - 933037 - - - 0.3016 - 1.659 0.431 - 369 1 2 0 0.0003 9 0 0 0 1.24E+07 6.92E+06 - - - 3.6888 0.8527 221125_WJC_METTL3_EV_vs_WT_F07.03830.03830.2 6.19 12-Jul K.HGWTQGK[136.11].G "sp|Q5T3I0|GPTC4_HUMAN,tr|E9PPY4|E9PPY4_HUMAN,tr|F2Z3C6|F2Z3C6_HUMAN,tr|F8W895|F8W895_HUMAN,tr|A0A0A0MRK1|A0A0A0MRK1_HUMAN,tr|E9PAV9|E9PAV9_HUMAN" 6 820.4071 1.27 93193 3830 2 820.406879 411.2108 G patch domain-containing protein 4 OS=Homo sapiens OX=9606 GN=GPATCH4 PE=1 SV=2 8.76 1338.3 - 1.34E+06 - - - -0.3133 - 0.883 0.025 - 179.9 1 2 0 -0.0003 7 0 0 0 3.26E+07 2.56E+07 - - - -1.1687 0.951 221125_WJC_METTL3_EV_vs_WT_F07.03834.03834.2 3.8 14-May R.KLLSAEER.L "sp|Q99719|SEPT5_HUMAN,tr|G3XAH0|G3XAH0_HUMAN,tr|E7EQM7|E7EQM7_HUMAN,tr|E7EX32|E7EX32_HUMAN,tr|C9JM82|C9JM82_HUMAN,tr|E7EPG2|E7EPG2_HUMAN,tr|B4DJ62|B4DJ62_HUMAN,tr|F8W9E5|F8W9E5_HUMAN" 8 944.5291 4.2 93197 3834 2 944.530483 473.2718 Septin-5 OS=Homo sapiens OX=9606 GN=SEPTIN5 PE=1 SV=1 6.14 1338.5 - 1.14E+06 - - - 1.4695 - 1.116 0.09 - 77 2 2 0 0.0014 8 0 0 0 1.74E+07 4.14E+06 - - - -0.0982 0.9998 221125_WJC_METTL3_EV_vs_WT_F07.03837.03837.2 0.00932 16-Oct K.QVAQQEAER[166.11].A "sp|P35232|PHB_HUMAN,tr|C9JZ20|C9JZ20_HUMAN,tr|E7ESE2|E7ESE2_HUMAN,tr|E9PCW0|E9PCW0_HUMAN,tr|C9JW96|C9JW96_HUMAN" 5 1067.5235 1.31 93198 3837 2 1067.522783 534.769 Prohibitin OS=Homo sapiens OX=9606 GN=PHB PE=1 SV=1 4.53 1338.9 - 2.97E+06 - - - -0.6773 - 1.881 0.408 - 557.4 1 2 0 -0.0007 9 0 0 0 1.97E+08 1.50E+08 - - - 3.8821 0.9984 221125_WJC_METTL3_EV_vs_WT_F07.03838.03838.2 0.399 12-Jul R.K[136.11]LQAQMK[136.11].D "sp|P35580|MYH10_HUMAN,sp|P35749|MYH11_HUMAN,sp|P35579|MYH9_HUMAN" 3 861.5077 4.46 93199 3838 2 861.507817 431.7611 Myosin-10 OS=Homo sapiens OX=9606 GN=MYH10 PE=1 SV=3 10 1339 - 977670 - - - 0.1265 - 1.658 0.183 - 203.9 1 2 0 0.0001 7 0 0 0 6.04E+07 1.36E+07 - - - 1.9947 0.9998 221125_WJC_METTL3_EV_vs_WT_F07.03839.03839.2 0.000222 16-Dec K.QVAQQEAER.A "sp|P35232|PHB_HUMAN,tr|C9JZ20|C9JZ20_HUMAN,tr|E7ESE2|E7ESE2_HUMAN,tr|E9PCW0|E9PCW0_HUMAN,tr|C9JW96|C9JW96_HUMAN" 5 1057.5152 1.31 93200 3839 2 1057.516659 529.7649 Prohibitin OS=Homo sapiens OX=9606 GN=PHB PE=1 SV=1 4.53 1339 - 3.48E+06 - - - 1.3456 - 2.106 0.447 - 638.6 1 2 0 0.0014 9 0 0 0 1.97E+08 1.50E+08 - - - 4.4968 0.9994 221125_WJC_METTL3_EV_vs_WT_F07.03840.03840.2 0.0336 16-Aug K.LYEEGSNKR.L sp|P25788|PSA3_HUMAN 1 1094.5356 0.72 93201 3840 2 1094.535144 548.2751 Proteasome subunit alpha type-3 OS=Homo sapiens OX=9606 GN=PSMA3 PE=1 SV=2 6.14 1339.2 - 1.00E+06 - - - -0.4504 - 1.505 0.351 - 245.2 1 2 0 -0.0005 9 0 0 0 1.49E+07 2.07E+07 - - - 2.816 0.9996 221125_WJC_METTL3_EV_vs_WT_F07.03841.03841.2 0.000491 16-Jul K.GDNNAVDDR[166.11].G "sp|P67812|SC11A_HUMAN,sp|P0C7V7|SC11B_HUMAN,tr|H0YKT4|H0YKT4_HUMAN,tr|H0YNG3|H0YNG3_HUMAN,tr|H0YNX5|H0YNX5_HUMAN" 5 984.4136 1.32 93202 3841 2 984.41234 493.2141 Signal peptidase complex catalytic subunit SEC11A OS=Homo sapiens OX=9606 GN=SEC11A PE=1 SV=1 3.93 1339.2 - 584671 - - - -1.3013 - 1.572 0.456 - 281.5 1 2 0 -0.0013 9 0 0 0 1.05E+08 7.93E+07 - - - 3.7173 0.9973 221125_WJC_METTL3_EV_vs_WT_F07.03847.03847.2 0.000666 16-Jul K.GDNNAVDDR.G "sp|P67812|SC11A_HUMAN,sp|P0C7V7|SC11B_HUMAN,tr|H0YKT4|H0YKT4_HUMAN,tr|H0YNG3|H0YNG3_HUMAN,tr|H0YNX5|H0YNX5_HUMAN" 5 974.4054 1.32 93206 3847 2 974.402165 488.21 Signal peptidase complex catalytic subunit SEC11A OS=Homo sapiens OX=9606 GN=SEC11A PE=1 SV=1 3.93 1339.9 - 2.36E+06 - - - -3.2697 - 1.507 0.378 - 264.1 1 2 0 -0.0032 9 0 0 0 1.05E+08 7.96E+07 - - - 3.0184 0.9996 221125_WJC_METTL3_EV_vs_WT_F07.03849.03849.2 0.000468 16-Oct K.LYEEGSNK[136.11]R[166.11].L sp|P25788|PSA3_HUMAN 1 1112.5581 0.72 93208 3849 2 1112.55689 557.2863 Proteasome subunit alpha type-3 OS=Homo sapiens OX=9606 GN=PSMA3 PE=1 SV=2 6.14 1340 - 1.69E+06 - - - -1.0939 - 1.73 0.389 - 408.6 1 2 0 -0.0012 9 0 0 0 1.49E+07 2.07E+07 - - - 3.4995 0.9829 221125_WJC_METTL3_EV_vs_WT_F07.03851.03851.2 0.0022 20-Aug R.ADAGHAGVSAN.M sp|Q9Y657|SPIN1_HUMAN 1 968.4312 - 93210 3851 2 968.430202 485.2229 Spindlin-1 OS=Homo sapiens OX=9606 GN=SPIN1 PE=1 SV=3 5.08 1340.2 - 1.31E+06 - - - -1.0016 - 1.668 0.462 - 169.3 1 1 0 -0.001 11 0 0 0 - - - - - 3.8371 0.9881 221125_WJC_METTL3_EV_vs_WT_F07.03852.03852.2 0.293 12-Jul K.KAPFQNK.Q sp|Q96KR1|ZFR_HUMAN 1 831.4603 1.39 93211 3852 2 831.458622 416.7374 Zinc finger RNA-binding protein OS=Homo sapiens OX=9606 GN=ZFR PE=1 SV=2 10 1340.3 - 1.23E+06 - - - -2.0025 - 1.389 0.128 - 202.1 1 2 0 -0.0017 7 0 0 0 8.52E+07 6.12E+07 - - - 1.027 0.9687 221125_WJC_METTL3_EV_vs_WT_F07.03862.03862.2 0.49 14-Aug F.LSC[160.03]SEDNR.L "sp|Q9BQA1|MEP50_HUMAN,tr|H0Y711|H0Y711_HUMAN" 2 979.4029 1.82 93219 3862 2 979.401952 490.7087 Methylosome protein 50 OS=Homo sapiens OX=9606 GN=WDR77 PE=1 SV=1 4.37 1341.3 - 1.39E+06 - - - -0.9771 - 1.66 0.346 - 310.5 1 1 0 -0.001 8 0 0 0 1.43E+07 7.86E+06 - - - 3.1248 0.9952 221125_WJC_METTL3_EV_vs_WT_F07.03864.03864.2 0.000544 18-Aug R.MNSTGGQTPR.R "sp|Q96ST2|IWS1_HUMAN,tr|A0A1B0GW95|A0A1B0GW95_HUMAN" 2 1047.4767 2.77 93221 3864 2 1047.47248 524.7456 Protein IWS1 homolog OS=Homo sapiens OX=9606 GN=IWS1 PE=1 SV=2 9.5 1341.5 - 354115 - - - -4.0688 - 1.556 0.375 - 113.1 1 2 0 -0.0043 10 0 0 0 6.87E+06 2.48E+06 - - - 3.0435 0.9913 221125_WJC_METTL3_EV_vs_WT_F07.03867.03867.2 0.178 12-Jun K.HGWTQGK.G "sp|Q5T3I0|GPTC4_HUMAN,tr|E9PPY4|E9PPY4_HUMAN,tr|F2Z3C6|F2Z3C6_HUMAN,tr|F8W895|F8W895_HUMAN,tr|A0A0A0MRK1|A0A0A0MRK1_HUMAN,tr|E9PAV9|E9PAV9_HUMAN" 6 812.3929 1.24 93223 3867 2 812.392382 407.2037 G patch domain-containing protein 4 OS=Homo sapiens OX=9606 GN=GPATCH4 PE=1 SV=2 8.76 1341.8 - 1.64E+06 - - - -0.6819 - 1.277 0.128 - 124.3 1 2 0 -0.0006 7 0 0 0 3.16E+07 2.55E+07 - - - 0.761 0.9997 221125_WJC_METTL3_EV_vs_WT_F07.03872.03872.2 0.0196 18-Oct K.DSAATTDEER.Q "sp|Q16531|DDB1_HUMAN,tr|A0A7P0TAK7|A0A7P0TAK7_HUMAN,tr|A0A7P0T870|A0A7P0T870_HUMAN,tr|A0A7P0TB30|A0A7P0TB30_HUMAN,tr|A0A7P0Z3Z5|A0A7P0Z3Z5_HUMAN,tr|F5GY55|F5GY55_HUMAN,tr|A0A7P0Z4B9|A0A7P0Z4B9_HUMAN,tr|A0A7P0T965|A0A7P0T965_HUMAN" 8 1093.4524 0.81 93227 3872 2 1093.450474 547.7335 DNA damage-binding protein 1 OS=Homo sapiens OX=9606 GN=DDB1 PE=1 SV=1 3.92 1342.3 - 805043 - - - -1.7257 - 2.257 0.439 - 510.3 1 2 0 -0.0019 10 0 0 0 3.41E+07 4.20E+07 - - - 4.5551 0.9595 221125_WJC_METTL3_EV_vs_WT_F07.03874.03874.2 0.0963 14-Jul R.ATVNQDTR.L "sp|P14868|SYDC_HUMAN,tr|C9J7S3|C9J7S3_HUMAN,tr|C9JLC1|C9JLC1_HUMAN" 3 903.441 2.43 93228 3874 2 903.445541 452.7278 "Aspartate--tRNA ligase, cytoplasmic OS=Homo sapiens OX=9606 GN=DARS1 PE=1 SV=2" 5.88 1342.5 - 1.49E+06 - - - 5.0164 - 1.481 0.207 - 170.7 1 2 0 0.0045 8 0 0 0 4.28E+07 1.76E+07 - - - 1.7529 0.9984 221125_WJC_METTL3_EV_vs_WT_F07.03876.03876.2 0.0697 12-Jul K.HPELADK[136.11].N "sp|Q9NQ39|RS10L_HUMAN,sp|P46783|RS10_HUMAN,tr|A0A2R8Y6L3|A0A2R8Y6L3_HUMAN,tr|F6U211|F6U211_HUMAN,tr|A0A1W2PQS6|A0A1W2PQS6_HUMAN,tr|A0A2R8YFH6|A0A2R8YFH6_HUMAN,tr|A0A2R8Y7H1|A0A2R8Y7H1_HUMAN,tr|S4R435|S4R435_HUMAN" 8 816.4221 1.21 93229 3876 2 816.421236 409.2183 Putative 40S ribosomal protein S10-like OS=Homo sapiens OX=9606 GN=RPS10P5 PE=5 SV=1 5.32 1342.7 - 1.49E+06 - - - -1.0803 - 1.247 0.327 - 147.7 1 2 0 -0.0009 7 0 0 0 5.03E+09 4.14E+09 - - - 2.1554 0.9078 221125_WJC_METTL3_EV_vs_WT_F07.03877.03877.2 0.362 20-Jun T.LGQAQAHSQEQ.- sp|Q96I24|FUBP3_HUMAN 1 1195.5582 - 93230 3877 2 1195.559129 598.7864 Far upstream element-binding protein 3 OS=Homo sapiens OX=9606 GN=FUBP3 PE=1 SV=2 5.24 1342.9 - 1.10E+06 - - - 0.8072 - 1.684 0.24 - 105.6 2 1 0 0.001 11 0 0 0 - - - - - 2.0888 0.9892 221125_WJC_METTL3_EV_vs_WT_F07.03878.03878.2 2.58 12-Jul K.R[166.11]QELVTK[136.11].L "sp|P04843|RPN1_HUMAN,tr|B7Z4L4|B7Z4L4_HUMAN" 2 890.5304 1.39 93231 3878 2 890.5292 446.2725 Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit 1 OS=Homo sapiens OX=9606 GN=RPN1 PE=1 SV=1 8.75 1342.9 - 7.13E+06 - - - -1.3879 - 1.363 0.108 - 213.8 1 2 0 -0.0012 7 0 0 0 3.24E+08 2.34E+08 - - - 0.8196 0.9972 221125_WJC_METTL3_EV_vs_WT_F07.03883.03883.2 0.0796 12-Aug K.K[136.11]APFQNK[136.11].Q sp|Q96KR1|ZFR_HUMAN 1 847.4887 1.38 93234 3883 2 847.487525 424.7516 Zinc finger RNA-binding protein OS=Homo sapiens OX=9606 GN=ZFR PE=1 SV=2 10 1343.5 - 3.99E+06 - - - -1.3711 - 1.706 0.146 - 286.8 1 2 0 -0.0012 7 0 0 0 8.67E+07 6.28E+07 - - - 1.8115 0.999 221125_WJC_METTL3_EV_vs_WT_F07.03884.03884.2 0.0787 12-Nov K.HPELADK.N "sp|Q9NQ39|RS10L_HUMAN,sp|P46783|RS10_HUMAN,tr|A0A2R8Y6L3|A0A2R8Y6L3_HUMAN,tr|F6U211|F6U211_HUMAN,tr|A0A1W2PQS6|A0A1W2PQS6_HUMAN,tr|A0A2R8YFH6|A0A2R8YFH6_HUMAN,tr|A0A2R8Y7H1|A0A2R8Y7H1_HUMAN,tr|S4R435|S4R435_HUMAN" 8 808.4079 1.21 93235 3884 2 808.405996 405.2112 Putative 40S ribosomal protein S10-like OS=Homo sapiens OX=9606 GN=RPS10P5 PE=5 SV=1 5.32 1343.5 - 3.18E+06 - - - -2.3775 - 1.987 0.287 - 352.6 1 2 0 -0.0019 7 0 0 0 5.03E+09 4.14E+09 - - - 3.3358 0.9875 221125_WJC_METTL3_EV_vs_WT_F07.03885.03885.2 0.0363 18-Jul R.AAPTSAPPSK.S "sp|Q13123|RED_HUMAN,tr|D6RAY9|D6RAY9_HUMAN,tr|D6REL4|D6REL4_HUMAN,tr|E7EQZ7|E7EQZ7_HUMAN,tr|D6RCQ4|D6RCQ4_HUMAN" 5 925.4869 1.19 93236 3885 2 925.485514 463.7507 Protein Red OS=Homo sapiens OX=9606 GN=IK PE=1 SV=3 8.8 1343.6 - 1.28E+06 - - - -1.4933 - 1.431 0.116 - 121 2 2 0 -0.0014 10 0 0 0 1.78E+08 1.50E+08 - - - 0.7632 0.9967 221125_WJC_METTL3_EV_vs_WT_F07.03895.03895.2 2.72 12-Aug R.LNVEEKK.T "sp|Q13283|G3BP1_HUMAN,sp|Q9UN86|G3BP2_HUMAN,tr|A0A7I2YQF2|A0A7I2YQF2_HUMAN,tr|A0A7I2V5M7|A0A7I2V5M7_HUMAN,tr|A0A7I2V647|A0A7I2V647_HUMAN,tr|A0A7I2YQM1|A0A7I2YQM1_HUMAN,tr|A0A7I2YQD9|A0A7I2YQD9_HUMAN,tr|A0A7I2YQR4|A0A7I2YQR4_HUMAN,tr|A0A7I2YQH0|A0A7I2YQH0_HUMAN,tr|A0A7I2V3P9|A0A7I2V3P9_HUMAN" 10 858.4811 0.88 93244 3895 2 858.480272 430.2478 Ras GTPase-activating protein-binding protein 1 OS=Homo sapiens OX=9606 GN=G3BP1 PE=1 SV=1 6.14 1344.6 - 3.58E+06 - - - -0.9447 - 1.639 0.125 - 215.4 1 2 0 -0.0008 7 0 0 0 6.46E+07 7.37E+07 - - - 1.5295 0.9998 221125_WJC_METTL3_EV_vs_WT_F07.03896.03896.2 3.60E-05 18-Sep K.DSAATTDEER[166.11].Q "sp|Q16531|DDB1_HUMAN,tr|A0A7P0TAK7|A0A7P0TAK7_HUMAN,tr|A0A7P0T870|A0A7P0T870_HUMAN,tr|A0A7P0TB30|A0A7P0TB30_HUMAN,tr|A0A7P0Z3Z5|A0A7P0Z3Z5_HUMAN,tr|F5GY55|F5GY55_HUMAN,tr|A0A7P0Z4B9|A0A7P0Z4B9_HUMAN,tr|A0A7P0T965|A0A7P0T965_HUMAN" 8 1103.4606 0.81 93245 3896 2 1103.460125 552.7376 DNA damage-binding protein 1 OS=Homo sapiens OX=9606 GN=DDB1 PE=1 SV=1 3.92 1344.7 - 3.13E+06 - - - -0.4586 - 2.001 0.466 - 399 1 2 0 -0.0005 10 0 0 0 3.41E+07 4.20E+07 - - - 4.4189 0.9978 221125_WJC_METTL3_EV_vs_WT_F07.03897.03897.2 0.0171 14-Aug K.QYTSQTTR[166.11].L "sp|Q69YN4|VIR_HUMAN,tr|H0YBN5|H0YBN5_HUMAN" 2 993.4755 0.33 93246 3897 2 993.472407 497.745 Protein virilizer homolog OS=Homo sapiens OX=9606 GN=VIRMA PE=1 SV=2 8.75 1344.7 - 952844 - - - -3.1063 - 1.604 0.358 - 324.9 1 2 0 -0.0031 8 0 0 0 4.50E+06 1.38E+07 - - - 3.1093 0.9595 221125_WJC_METTL3_EV_vs_WT_F07.03901.03901.2 1.19 12-Jul K.SVHELEK.S sp|P35579|MYH9_HUMAN 1 840.4341 1.07 93249 3901 2 840.433013 421.2243 Myosin-9 OS=Homo sapiens OX=9606 GN=MYH9 PE=1 SV=4 5.38 1345.1 - 1.82E+06 - - - -1.3315 - 1.029 0.106 - 208.1 1 2 0 -0.0011 7 0 0 0 1.97E+07 1.85E+07 - - - -0.0859 0.9994 221125_WJC_METTL3_EV_vs_WT_F07.03902.03902.2 0.0202 14-Jul K.YPDSHQPR.L "sp|O00165|HAX1_HUMAN,tr|E9PIQ7|E9PIQ7_HUMAN" 2 998.457 0.53 93250 3902 2 998.456281 500.2358 HCLS1-associated protein X-1 OS=Homo sapiens OX=9606 GN=HAX1 PE=1 SV=2 6.74 1345.2 - 1.01E+06 - - - -0.7131 - 1.337 0.412 - 234.5 1 2 0 -0.0007 8 0 0 0 6.48E+07 1.22E+08 - - - 2.9597 0.9998 221125_WJC_METTL3_EV_vs_WT_F07.03903.03903.2 0.000544 24-Dec R.AAPASSAGASDAR.L sp|Q8NF37|PCAT1_HUMAN 1 1130.5316 1.14 93251 3903 2 1130.532002 566.2731 Lysophosphatidylcholine acyltransferase 1 OS=Homo sapiens OX=9606 GN=LPCAT1 PE=1 SV=2 5.88 1345.3 - 559697 - - - 0.3423 - 2.123 0.479 - 563 1 2 0 0.0004 13 0 0 0 1.77E+07 1.56E+07 - - - 4.5109 0.9987 221125_WJC_METTL3_EV_vs_WT_F07.03913.03913.2 0.0147 16-Jul R.TVQQVNQEK[136.11].Q "sp|Q92878|RAD50_HUMAN,tr|A0A494C1B7|A0A494C1B7_HUMAN,tr|A0A1W2PQ90|A0A1W2PQ90_HUMAN" 3 1080.5655 0.89 93259 3913 2 1080.564186 541.29 DNA repair protein RAD50 OS=Homo sapiens OX=9606 GN=RAD50 PE=1 SV=1 5.66 1346.2 - 458299 - - - -1.204 - 1.578 0.276 - 101.5 1 2 0 -0.0013 9 0 0 0 4.79E+07 5.37E+07 - - - 2.3988 0.9999 221125_WJC_METTL3_EV_vs_WT_F07.03917.03917.3 0.000234 Nov-36 R.ILHENTQTDK[136.11].A "sp|Q6UB35|C1TM_HUMAN,tr|A0A087WVM4|A0A087WVM4_HUMAN,tr|B7ZM99|B7ZM99_HUMAN" 3 1205.6132 1.01 93261 3917 3 1205.612497 402.8783 "Monofunctional C1-tetrahydrofolate synthase, mitochondrial OS=Homo sapiens OX=9606 GN=MTHFD1L PE=1 SV=1" 5.32 1346.7 - 4.08E+06 - - - -0.5549 - 1.973 0.46 - 119.2 1 2 0 -0.0007 10 0 0 0 4.75E+07 4.70E+07 - - - 5.653 0.9993 221125_WJC_METTL3_EV_vs_WT_F07.03922.03922.2 0.000163 18-Nov R.ILHENTQTDK.A "sp|Q6UB35|C1TM_HUMAN,tr|A0A087WVM4|A0A087WVM4_HUMAN,tr|B7ZM99|B7ZM99_HUMAN" 3 1197.599 0.65 93265 3922 2 1197.601873 599.8068 "Monofunctional C1-tetrahydrofolate synthase, mitochondrial OS=Homo sapiens OX=9606 GN=MTHFD1L PE=1 SV=1" 5.32 1347.3 - 449380 - - - 2.4274 - 1.681 0.454 - 426.9 1 2 0 0.0029 10 0 0 0 6.19E+06 9.58E+06 - - - 3.8431 0.9979 221125_WJC_METTL3_EV_vs_WT_F07.03929.03929.3 0.00723 Oct-36 R.ILHENTQTDK.A "sp|Q6UB35|C1TM_HUMAN,tr|A0A087WVM4|A0A087WVM4_HUMAN,tr|B7ZM99|B7ZM99_HUMAN" 3 1197.599 1.01 93269 3929 3 1197.596389 400.2069 "Monofunctional C1-tetrahydrofolate synthase, mitochondrial OS=Homo sapiens OX=9606 GN=MTHFD1L PE=1 SV=1" 5.32 1348.2 - 3.26E+06 - - - -2.1518 - 1.569 0.307 - 111.7 1 2 0 -0.0026 10 0 0 0 4.75E+07 4.70E+07 - - - 3.2775 0.9991 221125_WJC_METTL3_EV_vs_WT_F07.03932.03932.2 0.00119 18-Sep R.ILHENTQTDK[136.11].A "sp|Q6UB35|C1TM_HUMAN,tr|A0A087WVM4|A0A087WVM4_HUMAN,tr|B7ZM99|B7ZM99_HUMAN" 3 1205.6132 0.65 93272 3932 2 1205.611378 603.8139 "Monofunctional C1-tetrahydrofolate synthase, mitochondrial OS=Homo sapiens OX=9606 GN=MTHFD1L PE=1 SV=1" 5.32 1348.5 - 969326 - - - -1.4831 - 1.531 0.361 - 192.7 1 2 0 -0.0018 10 0 0 0 6.19E+06 9.58E+06 - - - 2.8957 0.9974 221125_WJC_METTL3_EV_vs_WT_F07.03939.03939.2 0.144 16-Jul K.SSSAVAPQR.S sp|P31277|HXD11_HUMAN 1 901.4617 3.33 93276 3939 2 901.460297 451.7381 Homeobox protein Hox-D11 OS=Homo sapiens OX=9606 GN=HOXD11 PE=3 SV=3 9.47 1349.3 - 4.93E+06 - - - -1.6052 - 1.697 0.193 - 268.1 1 2 0 -0.0014 9 0 0 0 1.04E+08 3.12E+07 - - - 1.9961 0.9998 221125_WJC_METTL3_EV_vs_WT_F07.03944.03944.2 0.000377 24-Sep R.AAPASSAGASDAR[166.11].L sp|Q8NF37|PCAT1_HUMAN 1 1140.5399 1.14 93279 3944 2 1140.539671 571.2772 Lysophosphatidylcholine acyltransferase 1 OS=Homo sapiens OX=9606 GN=LPCAT1 PE=1 SV=2 5.88 1349.9 - 688725 - - - -0.1876 - 1.875 0.485 - 234.5 1 2 0 -0.0002 13 0 0 0 1.77E+07 1.56E+07 - - - 4.2365 0.9835 221125_WJC_METTL3_EV_vs_WT_F07.03951.03951.2 2.01 16-Aug R.TVQQVNQEK.Q "sp|Q92878|RAD50_HUMAN,tr|A0A494C1B7|A0A494C1B7_HUMAN,tr|A0A1W2PQ90|A0A1W2PQ90_HUMAN" 3 1072.5513 0.89 93284 3951 2 1072.549932 537.2829 DNA repair protein RAD50 OS=Homo sapiens OX=9606 GN=RAD50 PE=1 SV=1 5.66 1350.8 - 3.10E+06 - - - -1.2633 - 1.135 0.146 - 160.3 1 2 0 -0.0014 9 0 0 0 4.79E+07 5.38E+07 - - - 0.4853 0.9998 221125_WJC_METTL3_EV_vs_WT_F07.03952.03952.2 0.00222 16-Dec K.VEQHVVDGK[136.11].E sp|Q9Y3I0|RTCB_HUMAN 1 1017.5335 1.45 93285 3952 2 1017.53277 509.774 RNA-splicing ligase RtcB homolog OS=Homo sapiens OX=9606 GN=RTCB PE=1 SV=1 5.32 1350.9 - 1.07E+06 - - - -0.6771 - 2.384 0.392 - 637.6 1 2 0 -0.0007 9 0 0 0 2.38E+08 1.64E+08 - - - 4.4495 0.9998 221125_WJC_METTL3_EV_vs_WT_F07.03953.03953.2 8.90E-06 20-Oct K.NVATEGTSTQK.E "sp|Q9GZR7|DDX24_HUMAN,tr|G3V529|G3V529_HUMAN" 2 1134.5517 0.92 93286 3953 2 1134.550414 568.2831 ATP-dependent RNA helicase DDX24 OS=Homo sapiens OX=9606 GN=DDX24 PE=1 SV=1 6 1351 - 611034 - - - -1.1167 - 1.886 0.526 - 231.1 1 2 0 -0.0013 11 0 0 0 1.41E+07 1.53E+07 - - - 4.642 0.9956 221125_WJC_METTL3_EV_vs_WT_F07.03959.03959.2 0.544 16-Aug K.NRPGSALEK.E sp|P31930|QCR1_HUMAN 1 970.5196 1.45 93290 3959 2 970.51864 486.2671 "Cytochrome b-c1 complex subunit 1, mitochondrial OS=Homo sapiens OX=9606 GN=UQCRC1 PE=1 SV=3" 8.75 1351.7 - 6.68E+06 - - - -0.9819 - 1.546 0.137 - 277.9 1 2 0 -0.001 9 0 0 0 1.07E+08 7.39E+07 - - - 1.313 0.9998 221125_WJC_METTL3_EV_vs_WT_F07.03960.03960.2 0.000488 18-Sep R.AAPTSAPPSK[136.11].S "sp|Q13123|RED_HUMAN,tr|D6RAY9|D6RAY9_HUMAN,tr|D6REL4|D6REL4_HUMAN,tr|E7EQZ7|E7EQZ7_HUMAN,tr|D6RCQ4|D6RCQ4_HUMAN" 5 933.5011 1.27 93291 3960 2 933.500378 467.7578 Protein Red OS=Homo sapiens OX=9606 GN=IK PE=1 SV=3 8.8 1351.7 - 3.98E+06 - - - -0.7691 - 2.016 0.456 - 242 1 2 0 -0.0007 10 0 0 0 2.07E+08 1.62E+08 - - - 4.3658 0.9995 221125_WJC_METTL3_EV_vs_WT_F07.03961.03961.2 0.0645 16-Sep K.VAVATPAKK.A "sp|P19338|NUCL_HUMAN,tr|A0A7I2V506|A0A7I2V506_HUMAN,tr|A0A7I2V699|A0A7I2V699_HUMAN,tr|A0A7I2V2U7|A0A7I2V2U7_HUMAN,tr|A0A7I2V3F3|A0A7I2V3F3_HUMAN,tr|A0A7I2V428|A0A7I2V428_HUMAN,tr|A0A7I2V349|A0A7I2V349_HUMAN,tr|H7BY16|H7BY16_HUMAN,tr|A0A7I2V5M5|A0A7I2V5M5_HUMAN,tr|A0A7I2V2S8|A0A7I2V2S8_HUMAN,tr|C9JLB1|C9JLB1_HUMAN" 11 883.5491 0.95 93292 3961 2 883.548258 442.7818 Nucleolin OS=Homo sapiens OX=9606 GN=NCL PE=1 SV=3 10 1351.8 - 2.35E+06 - - - -0.9552 - 1.9 0.313 - 282.1 1 2 0 -0.0008 9 0 0 0 1.02E+08 1.08E+08 - - - 3.2095 0.9999 221125_WJC_METTL3_EV_vs_WT_F07.03964.03964.2 2.98E-05 13/20 K.ESGEGQGGYAK[136.11].E "sp|Q13423|NNTM_HUMAN,tr|E9PCX7|E9PCX7_HUMAN,tr|A0A590UK15|A0A590UK15_HUMAN,tr|A0A590UJM2|A0A590UJM2_HUMAN,tr|A0A590UK29|A0A590UK29_HUMAN,tr|A0A590UJI3|A0A590UJI3_HUMAN" 6 1089.4818 4.57 93295 3964 2 1089.481789 545.7482 "NAD(P) transhydrogenase, mitochondrial OS=Homo sapiens OX=9606 GN=NNT PE=1 SV=3" 4.53 1352.1 - 676861 - - - -0.0257 - 1.922 0.504 - 649.8 1 2 0 0 11 0 0 0 4.18E+07 9.13E+06 - - - 4.531 0.9487 221125_WJC_METTL3_EV_vs_WT_F07.03968.03968.2 1.41 12-Apr K.KDMMDIK.Y sp|Q96RL7|VP13A_HUMAN 1 879.4194 353.22 93297 3968 2 879.420604 440.717 Vacuolar protein sorting-associated protein 13A OS=Homo sapiens OX=9606 GN=VPS13A PE=1 SV=2 5.96 1352.6 - 2.20E+07 - - - 1.3577 - 0.901 0.152 - 100.9 1 2 0 0.0012 7 0 0 0 1.51E+10 4.27E+07 - - - -0.167 0.9948 221125_WJC_METTL3_EV_vs_WT_F07.03971.03971.2 0.123 14-Jul R.YDSSNQVK.G "sp|O95983|MBD3_HUMAN,tr|A0A087X1H1|A0A087X1H1_HUMAN,tr|K7EIE8|K7EIE8_HUMAN,tr|A0A087WT34|A0A087WT34_HUMAN,tr|A0A0A0MTS6|A0A0A0MTS6_HUMAN,tr|A0A087WZ12|A0A087WZ12_HUMAN" 6 939.4298 1.5 93300 3971 2 939.429284 470.7222 Methyl-CpG-binding domain protein 3 OS=Homo sapiens OX=9606 GN=MBD3 PE=1 SV=1 5.83 1352.8 - 2.06E+06 - - - -0.5227 - 1.095 0.241 - 99.7 1 2 0 -0.0005 8 0 0 0 6.34E+07 4.24E+07 - - - 1.0946 0.9275 221125_WJC_METTL3_EV_vs_WT_F07.03972.03972.2 0.0757 14-Jul R.YDSSNQVK[136.11].G "sp|O95983|MBD3_HUMAN,tr|A0A087X1H1|A0A087X1H1_HUMAN,tr|K7EIE8|K7EIE8_HUMAN,tr|A0A087WT34|A0A087WT34_HUMAN,tr|A0A0A0MTS6|A0A0A0MTS6_HUMAN,tr|A0A087WZ12|A0A087WZ12_HUMAN" 6 947.444 1.5 93301 3972 2 947.442657 474.7293 Methyl-CpG-binding domain protein 3 OS=Homo sapiens OX=9606 GN=MBD3 PE=1 SV=1 5.83 1352.8 - 940954 - - - -1.3911 - 1.106 0.028 - 80 1 2 0 -0.0013 8 0 0 0 6.36E+07 4.24E+07 - - - -0.4487 0.9726 221125_WJC_METTL3_EV_vs_WT_F07.03973.03973.2 0.915 18-Jun K.AQEEQTSSSK[136.11].G sp|Q4G0P3|HYDIN_HUMAN 1 1101.5029 0 93302 3973 2 1101.502265 551.7587 Hydrocephalus-inducing protein homolog OS=Homo sapiens OX=9606 GN=HYDIN PE=1 SV=3 4.53 1353 - 850588 - - - -0.6192 - 1.297 0.048 - 170.2 2 2 0 -0.0007 10 0 0 0 8.28E+04 4.24E+07 - - - -0.0133 0.9997 221125_WJC_METTL3_EV_vs_WT_F07.03974.03974.2 0.000836 20-Nov K.ESGEGQGGYAK.E "sp|Q13423|NNTM_HUMAN,tr|E9PCX7|E9PCX7_HUMAN,tr|A0A590UK15|A0A590UK15_HUMAN,tr|A0A590UJM2|A0A590UJM2_HUMAN,tr|A0A590UK29|A0A590UK29_HUMAN,tr|A0A590UJI3|A0A590UJI3_HUMAN" 6 1081.4676 4.7 93303 3974 2 1081.468387 541.7411 "NAD(P) transhydrogenase, mitochondrial OS=Homo sapiens OX=9606 GN=NNT PE=1 SV=3" 4.53 1353.1 - 818964 - - - 0.712 - 1.744 0.435 - 433.6 1 2 0 0.0008 11 0 0 0 4.29E+07 9.13E+06 - - - 3.7583 0.9986 221125_WJC_METTL3_EV_vs_WT_F07.03977.03977.2 0.0128 12-Aug K.AAVHYDR[166.11].S "sp|Q86V81|THOC4_HUMAN,tr|E9PB61|E9PB61_HUMAN" 2 840.4118 0.69 93304 3977 2 840.410433 421.2132 THO complex subunit 4 OS=Homo sapiens OX=9606 GN=ALYREF PE=1 SV=3 6.79 1353.5 - 1.96E+07 - - - -1.5921 - 1.476 0.301 - 323.9 1 2 0 -0.0013 7 0 0 0 1.66E+09 2.40E+09 - - - 2.4974 0.9994 221125_WJC_METTL3_EV_vs_WT_F07.03978.03978.2 0.0109 12-Jul K.AAVHYDR.S "sp|Q86V81|THOC4_HUMAN,tr|E9PB61|E9PB61_HUMAN" 2 830.4035 0.69 93305 3978 2 830.402362 416.209 THO complex subunit 4 OS=Homo sapiens OX=9606 GN=ALYREF PE=1 SV=3 6.79 1353.5 - 1.02E+07 - - - -1.3716 - 1.495 0.382 - 231.8 1 2 0 -0.0011 7 0 0 0 1.66E+09 2.40E+09 - - - 3.1363 0.9662 221125_WJC_METTL3_EV_vs_WT_F07.03980.03980.2 0.00167 14-Sep V.EQHVVDGK.E sp|Q9Y3I0|RTCB_HUMAN 1 910.4508 1.18 93307 3980 2 910.449043 456.2327 RNA-splicing ligase RtcB homolog OS=Homo sapiens OX=9606 GN=RTCB PE=1 SV=1 5.32 1353.6 - 5.05E+06 - - - -1.9792 - 1.696 0.413 - 377.4 1 1 0 -0.0018 8 0 0 0 1.01E+08 8.55E+07 - - - 3.6841 0.9904 221125_WJC_METTL3_EV_vs_WT_F07.03983.03983.2 0.00264 16-Jul R.VAC[160.03]SC[160.03]PNC[160.03]R.E "sp|Q02446|SP4_HUMAN,tr|A0A3B3IRW4|A0A3B3IRW4_HUMAN" 2 1122.4369 1.46 93310 3983 2 1122.434143 562.2257 Transcription factor Sp4 OS=Homo sapiens OX=9606 GN=SP4 PE=1 SV=2 7.94 1353.9 - 251564 - - - -2.4286 - 1.447 0.176 - 224.9 1 2 0 -0.0027 9 0 0 0 4.69E+06 3.21E+06 - - - 1.409 0.9964 221125_WJC_METTL3_EV_vs_WT_F07.03986.03986.2 0.128 12-Jun R.R[166.11]C[160.03]DDLTR[166.11].R "sp|Q92841|DDX17_HUMAN,tr|A0A5H1ZRQ2|A0A5H1ZRQ2_HUMAN,tr|A0A1X7SBZ2|A0A1X7SBZ2_HUMAN" 3 954.4456 0.95 93311 3986 2 954.445567 478.2301 Probable ATP-dependent RNA helicase DDX17 OS=Homo sapiens OX=9606 GN=DDX17 PE=1 SV=2 5.95 1354.3 - 1.93E+06 - - - -0.0388 - 1.187 0.238 - 130.4 1 2 0 0 7 0 0 0 2.91E+07 3.07E+07 - - - 1.342 0.9972 221125_WJC_METTL3_EV_vs_WT_F07.03991.03991.2 0.0429 14-Jul R.ETC[160.03]VEC[160.03]QK.T "sp|Q9UHB6|LIMA1_HUMAN,tr|F8VQE1|F8VQE1_HUMAN,tr|F8VS07|F8VS07_HUMAN" 3 1052.4267 1.11 93314 3991 2 1052.425951 527.2206 LIM domain and actin-binding protein 1 OS=Homo sapiens OX=9606 GN=LIMA1 PE=1 SV=1 4.53 1354.9 - 1.35E+06 - - - -0.6936 - 1.194 0.272 - 149.1 1 2 0 -0.0007 8 0 0 0 6.73E+07 6.08E+07 - - - 1.5845 0.9658 221125_WJC_METTL3_EV_vs_WT_F07.03993.03993.2 0.00255 14-Sep V.EQHVVDGK[136.11].E sp|Q9Y3I0|RTCB_HUMAN 1 918.465 1.21 93315 3993 2 918.463508 460.2398 RNA-splicing ligase RtcB homolog OS=Homo sapiens OX=9606 GN=RTCB PE=1 SV=1 5.32 1355.1 - 3.83E+06 - - - -1.6734 - 1.641 0.392 - 389 1 1 0 -0.0015 8 0 0 0 1.05E+08 8.64E+07 - - - 3.4296 0.9846 221125_WJC_METTL3_EV_vs_WT_F07.03995.03995.2 0.000154 16-Nov T.VHAITATQK.T "sp|P04406|G3P_HUMAN,tr|E7EUT5|E7EUT5_HUMAN" 2 967.5451 0.92 93316 3995 2 967.543712 484.7798 Glyceraldehyde-3-phosphate dehydrogenase OS=Homo sapiens OX=9606 GN=GAPDH PE=1 SV=3 8.73 1355.4 - 5.01E+06 - - - -1.4139 - 2.064 0.422 - 491.9 1 1 0 -0.0014 9 0 0 0 1.73E+08 1.88E+08 - - - 4.2539 0.9967 221125_WJC_METTL3_EV_vs_WT_F07.04000.04000.2 0.0121 14-Jul R.ETC[160.03]VEC[160.03]QK[136.11].T "sp|Q9UHB6|LIMA1_HUMAN,tr|F8VQE1|F8VQE1_HUMAN,tr|F8VS07|F8VS07_HUMAN" 3 1060.4409 1.11 93319 4000 2 1060.438895 531.2277 LIM domain and actin-binding protein 1 OS=Homo sapiens OX=9606 GN=LIMA1 PE=1 SV=1 4.53 1355.9 - 2.50E+06 - - - -1.8728 - 1.259 0.298 - 206.3 1 2 0 -0.002 8 0 0 0 6.73E+07 6.08E+07 - - - 1.936 0.9206 221125_WJC_METTL3_EV_vs_WT_F07.04006.04006.2 0.000463 16-Oct T.VHAITATQK[136.11].T "sp|P04406|G3P_HUMAN,tr|E7EUT5|E7EUT5_HUMAN" 2 975.5593 0.95 93324 4006 2 975.557865 488.7869 Glyceraldehyde-3-phosphate dehydrogenase OS=Homo sapiens OX=9606 GN=GAPDH PE=1 SV=3 8.73 1356.5 - 9.11E+06 - - - -1.4505 - 1.863 0.213 - 414.5 1 1 0 -0.0014 9 0 0 0 1.80E+08 1.89E+08 - - - 2.4138 0.9994 221125_WJC_METTL3_EV_vs_WT_F07.04010.04010.2 0.0111 16-Sep K.AEVPEDK[136.11]PK[136.11].A "sp|O95757|HS74L_HUMAN,tr|E9PDE8|E9PDE8_HUMAN" 2 1027.5521 0.45 93327 4010 2 1027.551025 514.7833 Heat shock 70 kDa protein 4L OS=Homo sapiens OX=9606 GN=HSPA4L PE=1 SV=3 4.68 1356.8 - 2.58E+06 - - - -1.0228 - 1.812 0.316 - 291.3 1 2 0 -0.0011 9 0 0 0 3.96E+07 8.82E+07 - - - 3.0944 0.9781 221125_WJC_METTL3_EV_vs_WT_F07.04020.04020.2 0.00311 14-Jul L.QQVDTSTR.T sp|P04264|K2C1_HUMAN 1 933.4516 141.85 93332 4020 2 933.450475 467.7331 "Keratin, type II cytoskeletal 1 OS=Homo sapiens OX=9606 GN=KRT1 PE=1 SV=6" 5.84 1358 - 5.65E+06 - - - -1.1763 - 1.495 0.457 - 313.3 1 1 0 -0.0011 8 0 0 0 3.92E+08 2.77E+06 - - - 3.6289 0.8119 221125_WJC_METTL3_EV_vs_WT_F07.04021.04021.2 0.043 14-Aug L.TEAKPVDK.V "sp|P52815|RM12_HUMAN,tr|B4DLN1|B4DLN1_HUMAN" 2 886.476 2.3 93333 4021 2 886.474559 444.2453 "39S ribosomal protein L12, mitochondrial OS=Homo sapiens OX=9606 GN=MRPL12 PE=1 SV=2" 5.73 1358.1 - 2.84E+06 - - - -1.6222 - 1.149 0.301 - 225.2 1 1 0 -0.0014 8 0 0 0 4.49E+08 1.96E+08 - - - 1.6826 0.9978 221125_WJC_METTL3_EV_vs_WT_F07.04029.04029.2 0.0161 12-Aug R.KYAQAIK.A "sp|P78347|GTF2I_HUMAN,tr|A0A494C1K3|A0A494C1K3_HUMAN" 2 820.4807 1.67 93338 4029 2 820.480612 411.2476 General transcription factor II-I OS=Homo sapiens OX=9606 GN=GTF2I PE=1 SV=2 9.7 1359 - 7.87E+06 - - - -0.0938 - 1.824 0.103 - 208.4 1 2 0 -0.0001 7 0 0 0 2.13E+08 1.27E+08 - - - 1.7061 0.9995 221125_WJC_METTL3_EV_vs_WT_F07.04031.04031.2 9.09E-05 14-Aug K.SFATASHR[166.11].N "sp|Q9NYF8|BCLF1_HUMAN,tr|E9PKI6|E9PKI6_HUMAN,tr|A0A1W2PQ43|A0A1W2PQ43_HUMAN,tr|E9PK91|E9PK91_HUMAN,tr|E9PK09|E9PK09_HUMAN,tr|E9PQN2|E9PQN2_HUMAN" 6 885.4332 2 93339 4031 2 885.43195 443.7239 Bcl-2-associated transcription factor 1 OS=Homo sapiens OX=9606 GN=BCLAF1 PE=1 SV=2 9.49 1359.2 - 9.95E+06 - - - -1.4513 - 1.673 0.382 - 228.9 1 2 0 -0.0013 8 0 0 0 4.65E+09 2.33E+09 - - - 3.4141 0.9992 221125_WJC_METTL3_EV_vs_WT_F07.04035.04035.2 0.0199 14-Aug R.WSSTSSSK.L "sp|P49959|MRE11_HUMAN,tr|F8W7U8|F8W7U8_HUMAN" 2 868.3927 1.98 93343 4035 2 868.392144 435.2036 Double-strand break repair protein MRE11 OS=Homo sapiens OX=9606 GN=MRE11 PE=1 SV=3 8.75 1359.4 - 1.68E+06 - - - -0.5954 - 1.412 0.347 - 262.7 1 2 0 -0.0005 8 0 0 0 3.72E+07 1.88E+07 - - - 2.6443 0.9233 221125_WJC_METTL3_EV_vs_WT_F07.04039.04039.2 0.000643 14-Aug L.TEAK[136.11]PVDK[136.11].V "sp|P52815|RM12_HUMAN,tr|B4DLN1|B4DLN1_HUMAN" 2 902.5044 2.3 93345 4039 2 902.502449 452.2595 "39S ribosomal protein L12, mitochondrial OS=Homo sapiens OX=9606 GN=MRPL12 PE=1 SV=2" 5.73 1359.9 - 8.74E+06 - - - -2.1584 - 1.562 0.339 - 315.6 1 1 0 -0.0019 8 0 0 0 4.49E+08 1.95E+08 - - - 2.8893 0.9997 221125_WJC_METTL3_EV_vs_WT_F07.04050.04050.2 0.00171 18-Sep K.AITTQNC[160.03]NTK.C "sp|Q15796|SMAD2_HUMAN,tr|K7ESI8|K7ESI8_HUMAN,tr|K7ERC7|K7ERC7_HUMAN,tr|K7EJX0|K7EJX0_HUMAN,tr|K7EL92|K7EL92_HUMAN,tr|B7Z5N5|B7Z5N5_HUMAN" 6 1149.5448 1.11 93353 4050 2 1149.544238 575.7797 Mothers against decapentaplegic homolog 2 OS=Homo sapiens OX=9606 GN=SMAD2 PE=1 SV=1 8.27 1361.1 - 1.96E+06 - - - -0.508 - 1.696 0.435 - 233.8 1 2 0 -0.0006 10 0 0 0 4.90E+07 4.43E+07 - - - 3.7283 0.9994 221125_WJC_METTL3_EV_vs_WT_F07.04056.04056.2 0.293 16-Oct R.LTEAKPVDK.V "sp|P52815|RM12_HUMAN,tr|B4DLN1|B4DLN1_HUMAN" 2 999.5601 2.27 93356 4056 2 999.558817 500.7873 "39S ribosomal protein L12, mitochondrial OS=Homo sapiens OX=9606 GN=MRPL12 PE=1 SV=2" 6.07 1361.8 - 5.91E+07 - - - -1.2445 - 1.968 0.295 - 398.2 1 2 0 -0.0012 9 0 0 0 1.02E+09 4.48E+08 - - - 3.1781 0.9986 221125_WJC_METTL3_EV_vs_WT_F07.04062.04062.2 0.0471 16-Nov K.HVSNAPLTK.L "sp|Q8TAQ2|SMRC2_HUMAN,tr|F8VXC8|F8VXC8_HUMAN,tr|F8VZW6|F8VZW6_HUMAN" 3 965.5294 1.08 93359 4062 2 965.52743 483.772 SWI\SNF complex subunit SMARCC2 OS=Homo sapiens OX=9606 GN=SMARCC2 PE=1 SV=1 8.76 1362.4 - 2.65E+06 - - - -2.0714 - 1.702 0.3 - 420 1 2 0 -0.002 9 0 0 0 1.90E+08 1.76E+08 - - - 2.7947 0.9997 221125_WJC_METTL3_EV_vs_WT_F07.04064.04064.2 4.58E-05 14-Aug K.SFATASHR.N "sp|Q9NYF8|BCLF1_HUMAN,tr|E9PKI6|E9PKI6_HUMAN,tr|A0A1W2PQ43|A0A1W2PQ43_HUMAN,tr|E9PK91|E9PK91_HUMAN,tr|E9PK09|E9PK09_HUMAN,tr|E9PQN2|E9PQN2_HUMAN" 6 875.425 2 93361 4064 2 875.423999 438.7198 Bcl-2-associated transcription factor 1 OS=Homo sapiens OX=9606 GN=BCLAF1 PE=1 SV=2 9.49 1362.6 - 2.10E+08 - - - -1.1035 - 1.774 0.445 - 236.8 1 2 0 -0.001 8 0 0 0 4.65E+09 2.33E+09 - - - 4.0563 0.8809 221125_WJC_METTL3_EV_vs_WT_F07.04065.04065.2 0.343 12-Jun R.DTIEEHR[166.11].Q sp|P23381|SYWC_HUMAN 1 908.4227 0.99 93362 4065 2 908.42754 455.2186 "Tryptophan--tRNA ligase, cytoplasmic OS=Homo sapiens OX=9606 GN=WARS1 PE=1 SV=2" 4.65 1362.7 - 881560 - - - 5.296 - 1.395 0.127 - 174.3 1 2 0 0.0048 7 0 0 0 2.57E+07 2.58E+07 - - - 1.0323 0.9975 221125_WJC_METTL3_EV_vs_WT_F07.04069.04069.2 0.105 14-Jun K.GQSEEIQK.K "sp|P83731|RL24_HUMAN,tr|C9JNW5|C9JNW5_HUMAN,tr|C9JXB8|C9JXB8_HUMAN" 3 917.4454 1.04 93364 4069 2 917.443479 459.73 60S ribosomal protein L24 OS=Homo sapiens OX=9606 GN=RPL24 PE=1 SV=1 4.53 1363.1 - 2.40E+07 - - - -2.1211 - 1.496 0.281 - 180.9 1 2 0 -0.0019 8 0 0 0 3.82E+08 3.69E+08 - - - 2.3307 0.9963 221125_WJC_METTL3_EV_vs_WT_F07.04071.04071.2 0.0286 18-Oct K.GLSSTEQTNK.S "sp|Q03112|MECOM_HUMAN,tr|E7EUL6|E7EUL6_HUMAN,tr|A0A0C3SFZ7|A0A0C3SFZ7_HUMAN" 3 1063.5146 1.05 93365 4071 2 1063.510773 532.7646 Histone-lysine N-methyltransferase MECOM OS=Homo sapiens OX=9606 GN=MECOM PE=1 SV=3 6 1363.3 - 630293 - - - -3.5684 - 1.655 0.336 - 259.6 1 2 0 -0.0038 10 0 0 0 6.25E+07 5.94E+07 - - - 2.9278 0.9897 221125_WJC_METTL3_EV_vs_WT_F07.04073.04073.2 0.0291 12-Jul R.DLVHSNK.K "sp|Q9Y2W1|TR150_HUMAN,tr|A0A3B3ITZ9|A0A3B3ITZ9_HUMAN" 2 811.4188 2.74 93366 4073 2 811.416661 406.7167 Thyroid hormone receptor-associated protein 3 OS=Homo sapiens OX=9606 GN=THRAP3 PE=1 SV=2 6.74 1363.6 - 2.97E+06 - - - -2.6571 - 1.342 0.204 - 204.6 1 2 0 -0.0022 7 0 0 0 7.28E+08 2.66E+08 - - - 1.4791 0.9152 221125_WJC_METTL3_EV_vs_WT_F07.04075.04075.2 0.0533 18-Jul K.GEVPPK[136.11]ETPK[136.11].K sp|P49006|MRP_HUMAN 1 1096.6099 0.35 93368 4075 2 1096.608758 549.3122 MARCKS-related protein OS=Homo sapiens OX=9606 GN=MARCKSL1 PE=1 SV=2 6.14 1363.8 - 1.03E+06 - - - -1.0642 - 1.241 0.17 - 164 1 2 1 -0.0012 10 0 0 0 5.53E+06 1.59E+07 - - - 0.8989 0.964 221125_WJC_METTL3_EV_vs_WT_F07.04079.04079.2 0.00187 12-Jul K.YHTINGH.N "sp|P51991|ROA3_HUMAN,sp|P22626|ROA2_HUMAN,tr|A0A024RA28|A0A024RA28_HUMAN,tr|A0A7I2V4N1|A0A7I2V4N1_HUMAN,tr|A0A7I2V5D8|A0A7I2V5D8_HUMAN,tr|A0A7I2V2R3|A0A7I2V2R3_HUMAN,tr|A0A7I2V4I6|A0A7I2V4I6_HUMAN,tr|A0A087WUI2|A0A087WUI2_HUMAN,tr|A0A7I2V4S4|A0A7I2V4S4_HUMAN,tr|A0A7I2V4J6|A0A7I2V4J6_HUMAN,tr|A0A7I2V323|A0A7I2V323_HUMAN,tr|A0A7I2V4G0|A0A7I2V4G0_HUMAN,tr|A0A7I2V3P1|A0A7I2V3P1_HUMAN,tr|A0A7I2V3P7|A0A7I2V3P7_HUMAN" 14 840.3879 - 93370 4079 2 840.385836 421.2012 Heterogeneous nuclear ribonucleoprotein A3 OS=Homo sapiens OX=9606 GN=HNRNPA3 PE=1 SV=2 6.92 1364.3 - 4.01E+06 - - - -2.3977 - 1.485 0.499 - 219.1 1 1 0 -0.002 7 0 0 0 - - - - - 3.9789 0.9995 221125_WJC_METTL3_EV_vs_WT_F07.04080.04080.2 0.00248 12-Aug R.HGSGEWR.Q sp|Q8IU81|I2BP1_HUMAN 1 827.3674 1.17 93371 4080 2 827.36557 414.691 Interferon regulatory factor 2-binding protein 1 OS=Homo sapiens OX=9606 GN=IRF2BP1 PE=1 SV=1 6.75 1364.4 - 1.61E+06 - - - -2.2723 - 1.634 0.471 - 179.7 1 2 0 -0.0019 7 0 0 0 2.06E+08 1.76E+08 - - - 4.0751 0.9919 221125_WJC_METTL3_EV_vs_WT_F07.04083.04083.2 0.0998 20-Oct R.SAQDGPAPAEK[136.11].R "sp|Q9BQ52|RNZ2_HUMAN,tr|G5E9D5|G5E9D5_HUMAN,tr|E7ES68|E7ES68_HUMAN,tr|H7C2I4|H7C2I4_HUMAN" 4 1077.5182 0.96 93374 4083 2 1077.513439 539.7664 Zinc phosphodiesterase ELAC protein 2 OS=Homo sapiens OX=9606 GN=ELAC2 PE=1 SV=2 4.37 1364.8 - 994051 - - - -4.4213 - 1.902 0.27 - 314.7 1 2 0 -0.0048 11 0 0 0 2.59E+07 2.70E+07 - - - 2.7729 0.9992 221125_WJC_METTL3_EV_vs_WT_F07.04089.04089.2 0.0296 16-Sep K.QVAPEK[136.11]PVK[136.11].K "sp|P53999|TCP4_HUMAN,tr|D6R970|D6R970_HUMAN,tr|D6RC37|D6RC37_HUMAN" 3 1010.6095 0.45 93378 4089 2 1010.608583 506.312 Activated RNA polymerase II transcriptional coactivator p15 OS=Homo sapiens OX=9606 GN=SUB1 PE=1 SV=3 8.59 1365.5 - 2.62E+06 - - - -0.938 - 1.573 0.316 - 386.3 1 2 0 -0.0009 9 0 0 0 2.65E+07 5.87E+07 - - - 2.6852 0.9996 221125_WJC_METTL3_EV_vs_WT_F07.04090.04090.2 0.00115 20-Aug K.TLQNTSSEGSR[166.11].L sp|Q06787|FMR1_HUMAN 1 1188.561 2.53 93379 4090 2 1188.558797 595.2878 Synaptic functional regulator FMR1 OS=Homo sapiens OX=9606 GN=FMR1 PE=1 SV=1 5.66 1365.6 - 419154 - - - -1.8653 - 1.859 0.466 - 184.5 1 2 0 -0.0022 11 0 0 0 3.41E+07 1.34E+07 - - - 4.1595 0.9794 221125_WJC_METTL3_EV_vs_WT_F07.04093.04093.2 0.27 12-Jul R.DLVHSNK[136.11].K "sp|Q9Y2W1|TR150_HUMAN,tr|A0A3B3ITZ9|A0A3B3ITZ9_HUMAN" 2 819.433 2.74 93380 4093 2 819.432124 410.7238 Thyroid hormone receptor-associated protein 3 OS=Homo sapiens OX=9606 GN=THRAP3 PE=1 SV=2 6.74 1366 - 9.46E+06 - - - -1.0898 - 1.247 0.073 - 199.7 1 2 0 -0.0009 7 0 0 0 7.28E+08 2.66E+08 - - - 0.2793 0.9134 221125_WJC_METTL3_EV_vs_WT_F07.04094.04094.2 2.51 16-Jun K.HVSNAPLTK[136.11].L "sp|Q8TAQ2|SMRC2_HUMAN,tr|F8VXC8|F8VXC8_HUMAN,tr|F8VZW6|F8VZW6_HUMAN" 3 973.5436 1.37 93381 4094 2 973.540921 487.7791 SWI\SNF complex subunit SMARCC2 OS=Homo sapiens OX=9606 GN=SMARCC2 PE=1 SV=1 8.76 1366.1 - 1.38E+06 - - - -2.7826 - 1.143 0.082 - 99.3 1 2 0 -0.0027 9 0 0 0 2.68E+08 1.95E+08 - - - 0.0325 0.9485 221125_WJC_METTL3_EV_vs_WT_F07.04096.04096.2 5.93 12-Jul K.AWKPSSK.R "sp|Q04637|IF4G1_HUMAN,tr|C9J2Z7|C9J2Z7_HUMAN,tr|E7EUU4|E7EUU4_HUMAN,tr|E9PGM1|E9PGM1_HUMAN,tr|C9J6B6|C9J6B6_HUMAN,tr|E7EX73|E7EX73_HUMAN,tr|C9K073|C9K073_HUMAN,tr|A0A7I2Y1C3|A0A7I2Y1C3_HUMAN,tr|C9JF13|C9JF13_HUMAN" 9 802.4337 0.59 93383 4096 2 802.432576 402.2241 Eukaryotic translation initiation factor 4 gamma 1 OS=Homo sapiens OX=9606 GN=EIF4G1 PE=1 SV=4 10 1366.2 - 1.90E+06 - - - -1.4481 - 1.049 0.082 - 224.3 1 2 0 -0.0012 7 0 0 0 4.91E+07 8.34E+07 - - - -0.2021 0.9995 221125_WJC_METTL3_EV_vs_WT_F07.04100.04100.2 1.15E-05 20-Nov K.TLQNTSSEGSR.L sp|Q06787|FMR1_HUMAN 1 1178.5527 2.53 93385 4100 2 1178.549433 590.2836 Synaptic functional regulator FMR1 OS=Homo sapiens OX=9606 GN=FMR1 PE=1 SV=1 5.66 1366.7 - 1.32E+06 - - - -2.8094 - 2.179 0.493 - 375.8 1 2 0 -0.0033 11 0 0 0 3.41E+07 1.34E+07 - - - 4.7883 0.9991 221125_WJC_METTL3_EV_vs_WT_F07.04102.04102.2 0.00382 14-Sep R.R[166.11]GYYNGTK[136.11].F sp|Q9Y3C6|PPIL1_HUMAN 1 975.4893 0.95 93386 4102 2 975.487935 488.7519 Peptidyl-prolyl cis-trans isomerase-like 1 OS=Homo sapiens OX=9606 GN=PPIL1 PE=1 SV=1 9.7 1366.9 - 1.42E+06 - - - -1.3983 - 1.777 0.276 - 315.7 1 2 0 -0.0014 8 0 0 0 3.27E+07 3.42E+07 - - - 2.8131 0.9998 221125_WJC_METTL3_EV_vs_WT_F07.04116.04116.2 0.000333 13/16 R.KSVLADQGK.S "sp|Q9NYF8|BCLF1_HUMAN,tr|E9PKI6|E9PKI6_HUMAN,tr|A0A1W2PQ43|A0A1W2PQ43_HUMAN,tr|E9PK91|E9PK91_HUMAN,tr|E9PK09|E9PK09_HUMAN,tr|E9PQN2|E9PQN2_HUMAN" 6 944.5291 1.98 93390 4116 2 944.527769 473.2718 Bcl-2-associated transcription factor 1 OS=Homo sapiens OX=9606 GN=BCLAF1 PE=1 SV=2 8.59 1368.9 - 2.24E+08 - - - -1.4039 - 2.411 0.439 - 515.1 1 2 0 -0.0013 9 0 0 0 6.93E+09 3.51E+09 - - - 4.829 0.9982 221125_WJC_METTL3_EV_vs_WT_F07.04131.04131.2 0.000481 14-Sep R.C[160.03]EQPTSPR.S "sp|A8K2U0|A2ML1_HUMAN,tr|H0YH14|H0YH14_HUMAN,tr|H0YGG5|H0YGG5_HUMAN" 3 973.4287 0.32 93398 4131 2 973.425688 487.7216 Alpha-2-macroglobulin-like protein 1 OS=Homo sapiens OX=9606 GN=A2ML1 PE=1 SV=3 5.99 1370.7 - 694809 - - - -3.125 - 1.407 0.445 - 293.8 1 2 0 -0.003 8 0 0 0 1.23E+07 3.85E+07 - - - 3.3566 0.9988 221125_WJC_METTL3_EV_vs_WT_F07.04135.04135.2 0.00561 16-Oct R.K[136.11]SVLADQGK.S "sp|Q9NYF8|BCLF1_HUMAN,tr|E9PKI6|E9PKI6_HUMAN,tr|A0A1W2PQ43|A0A1W2PQ43_HUMAN,tr|E9PK91|E9PK91_HUMAN,tr|E9PK09|E9PK09_HUMAN,tr|E9PQN2|E9PQN2_HUMAN" 6 952.5433 - 93400 4135 2 952.541288 477.2789 Bcl-2-associated transcription factor 1 OS=Homo sapiens OX=9606 GN=BCLAF1 PE=1 SV=2 8.59 1371.3 - 3.72E+06 - - - -2.107 - 1.96 0.275 - 229.2 1 2 0 -0.002 9 0 0 0 - - - - - 3.0184 0.9975 221125_WJC_METTL3_EV_vs_WT_F07.04137.04137.2 0.00188 13/16 K.HAAADEALK[136.11].L sp|O15226|NKRF_HUMAN 1 932.4807 1.04 93402 4137 2 932.485447 467.2476 NF-kappa-B-repressing factor OS=Homo sapiens OX=9606 GN=NKRF PE=1 SV=2 5.32 1371.3 - 8.49E+06 - - - 5.0961 - 2.376 0.459 - 579 1 2 0 0.0048 9 0 0 0 1.10E+08 1.06E+08 - - - 4.9334 0.9958 221125_WJC_METTL3_EV_vs_WT_F07.04139.04139.2 0.00219 18-Jul K.EAENPEGEEK[136.11].E sp|P51858|HDGF_HUMAN 1 1138.487 2.99 93404 4139 2 1138.482571 570.2508 Hepatoma-derived growth factor OS=Homo sapiens OX=9606 GN=HDGF PE=1 SV=1 3.98 1371.6 - 504811 - - - -3.8569 - 1.354 0.424 - 145.7 1 2 0 -0.0044 10 0 0 0 1.60E+07 5.36E+06 - - - 3.0172 0.9981 221125_WJC_METTL3_EV_vs_WT_F07.04142.04142.2 0.00364 14-Jul R.KAFEEAEK.N "sp|P55072|TERA_HUMAN,tr|A0A7P0Z4C6|A0A7P0Z4C6_HUMAN,tr|A0A7I2V2Y2|A0A7I2V2Y2_HUMAN,tr|A0A7P0T8Q5|A0A7P0T8Q5_HUMAN,tr|C9JUP7|C9JUP7_HUMAN,tr|A0A7P0TAW3|A0A7P0TAW3_HUMAN,tr|A0A7I2V540|A0A7I2V540_HUMAN,tr|A0A7P0T8A3|A0A7P0T8A3_HUMAN,tr|A0A7P0TAQ1|A0A7P0TAQ1_HUMAN,tr|A0A7I2V5G8|A0A7I2V5G8_HUMAN,tr|A0A7P0TAY0|A0A7P0TAY0_HUMAN" 11 950.4709 1.04 93405 4142 2 950.472583 476.2427 Transitional endoplasmic reticulum ATPase OS=Homo sapiens OX=9606 GN=VCP PE=1 SV=4 4.79 1372 - 2.98E+06 - - - 1.7581 - 1.557 0.276 - 122.9 1 2 0 0.0017 8 0 0 0 6.13E+07 5.92E+07 - - - 2.4144 0.9717 221125_WJC_METTL3_EV_vs_WT_F07.04152.04152.2 0.00244 16-Aug K.HGRPGIGAT.H "sp|P62841|RS15_HUMAN,tr|K7EM56|K7EM56_HUMAN,tr|A0A0B4J2B4|A0A0B4J2B4_HUMAN,tr|K7ELC2|K7ELC2_HUMAN,tr|K7EQJ5|K7EQJ5_HUMAN,tr|S4R417|S4R417_HUMAN" 6 864.4566 1.22 93413 4152 2 864.455388 433.2356 40S ribosomal protein S15 OS=Homo sapiens OX=9606 GN=RPS15 PE=1 SV=2 9.76 1373 - 3.06E+06 - - - -1.4009 - 1.372 0.475 - 136.5 1 1 0 -0.0012 9 0 0 0 2.25E+08 1.85E+08 - - - 3.464 0.9991 221125_WJC_METTL3_EV_vs_WT_F07.04155.04155.2 0.000177 18-Sep K.ELEAHSAEAR[166.11].A "sp|Q9BQG0|MBB1A_HUMAN,tr|I3L1L3|I3L1L3_HUMAN" 2 1121.5341 0.25 93416 4155 2 1121.531139 561.7743 Myb-binding protein 1A OS=Homo sapiens OX=9606 GN=MYBBP1A PE=1 SV=2 4.75 1373.4 - 501261 - - - -2.6143 - 1.733 0.419 - 352.8 1 2 0 -0.0029 10 0 0 0 4.69E+06 1.88E+07 - - - 3.6696 0.9922 221125_WJC_METTL3_EV_vs_WT_F07.04156.04156.2 0.0377 18-Jun K.EAENPEGEEK.E sp|P51858|HDGF_HUMAN 1 1130.4728 0.68 93417 4156 2 1130.470756 566.2437 Hepatoma-derived growth factor OS=Homo sapiens OX=9606 GN=HDGF PE=1 SV=1 3.98 1373.5 - 347988 - - - -1.7745 - 1.083 0.265 - 89.2 1 2 0 -0.002 10 0 0 0 3.18E+06 4.70E+06 - - - 1.2202 0.9996 221125_WJC_METTL3_EV_vs_WT_F07.04157.04157.2 0.00676 18-Oct K.ELEAHSAEAR.A "sp|Q9BQG0|MBB1A_HUMAN,tr|I3L1L3|I3L1L3_HUMAN" 2 1111.5258 0.2 93418 4157 2 1111.523083 556.7702 Myb-binding protein 1A OS=Homo sapiens OX=9606 GN=MYBBP1A PE=1 SV=2 4.75 1373.6 - 226701 - - - -2.4453 - 2.005 0.516 - 297.3 1 2 0 -0.0027 10 0 0 0 2.48E+06 1.24E+07 - - - 4.7931 0.9997 221125_WJC_METTL3_EV_vs_WT_F07.04164.04164.2 0.000546 16-Jul R.DMASNEGSR[166.11].L sp|P98175|RBM10_HUMAN 1 975.3955 3.22 93423 4164 2 975.394513 488.705 RNA-binding protein 10 OS=Homo sapiens OX=9606 GN=RBM10 PE=1 SV=3 4.37 1374.4 - 1.03E+06 - - - -1.0406 - 1.383 0.521 - 195.4 1 2 0 -0.001 9 0 0 0 3.16E+07 9.81E+06 - - - 3.8269 0.9997 221125_WJC_METTL3_EV_vs_WT_F07.04168.04168.2 4.23E-05 22-Nov R.AEASPNDTAGAR[166.11].T "sp|Q96RK0|CIC_HUMAN,tr|A0A0A0MQR4|A0A0A0MQR4_HUMAN,tr|I3L2J0|I3L2J0_HUMAN,tr|A0A7P0T9K5|A0A7P0T9K5_HUMAN" 4 1168.5348 1.75 93427 4168 2 1168.53178 585.2747 Protein capicua homolog OS=Homo sapiens OX=9606 GN=CIC PE=1 SV=2 4.37 1374.9 - 509344 - - - -2.5836 - 2.368 0.577 - 436.8 1 2 0 -0.003 12 0 0 0 7.89E+06 4.52E+06 - - - 5.57 0.9981 221125_WJC_METTL3_EV_vs_WT_F07.04169.04169.2 0.00117 22-Aug K.AGPATTTSSETR.Q sp|Q8NFC6|BD1L1_HUMAN 1 1177.5575 1.45 93428 4169 2 1177.554937 589.786 Biorientation of chromosomes in cell division protein 1-like 1 OS=Homo sapiens OX=9606 GN=BOD1L1 PE=1 SV=2 6.05 1375 - 423720 - - - -2.1723 - 1.523 0.33 - 177.6 1 2 0 -0.0026 12 0 0 0 7.20E+06 4.95E+06 - - - 2.5845 0.9994 221125_WJC_METTL3_EV_vs_WT_F07.04170.04170.2 0.772 22-Sep K.AGPATTTSSETR[166.11].Q sp|Q8NFC6|BD1L1_HUMAN 1 1187.5658 1.45 93429 4170 2 1187.564903 594.7902 Biorientation of chromosomes in cell division protein 1-like 1 OS=Homo sapiens OX=9606 GN=BOD1L1 PE=1 SV=2 6.05 1375.1 - 406032 - - - -0.7259 - 1.726 0.329 - 356.2 1 2 0 -0.0009 12 0 0 0 7.20E+06 4.95E+06 - - - 2.9068 0.9999 221125_WJC_METTL3_EV_vs_WT_F07.04174.04174.2 0.000153 16-Sep R.K[136.11]SVLADQGK[136.11].S "sp|Q9NYF8|BCLF1_HUMAN,tr|E9PKI6|E9PKI6_HUMAN,tr|A0A1W2PQ43|A0A1W2PQ43_HUMAN,tr|E9PK91|E9PK91_HUMAN,tr|E9PK09|E9PK09_HUMAN,tr|E9PQN2|E9PQN2_HUMAN" 6 960.5575 1.98 93431 4174 2 960.557972 481.286 Bcl-2-associated transcription factor 1 OS=Homo sapiens OX=9606 GN=BCLAF1 PE=1 SV=2 8.59 1375.6 - 7.87E+06 - - - 0.4966 - 2.115 0.469 - 253.6 1 2 0 0.0005 9 0 0 0 6.93E+09 3.51E+09 - - - 4.6719 0.9887 221125_WJC_METTL3_EV_vs_WT_F07.04175.04175.2 0.000265 16-Oct K.HGR[166.11]PGIGAT.H "sp|P62841|RS15_HUMAN,tr|K7EM56|K7EM56_HUMAN,tr|A0A0B4J2B4|A0A0B4J2B4_HUMAN,tr|K7ELC2|K7ELC2_HUMAN,tr|K7EQJ5|K7EQJ5_HUMAN,tr|S4R417|S4R417_HUMAN" 6 874.4649 1.48 93432 4175 2 874.464471 438.2397 40S ribosomal protein S15 OS=Homo sapiens OX=9606 GN=RPS15 PE=1 SV=2 9.76 1375.7 - 8.06E+06 - - - -0.4551 - 1.729 0.481 - 239.4 1 1 0 -0.0004 9 0 0 0 2.08E+08 1.40E+08 - - - 4.1776 0.9987 221125_WJC_METTL3_EV_vs_WT_F07.04176.04176.2 2.17 14-Aug R.AEIDNVKK.Q "sp|P13647|K2C5_HUMAN,tr|H0YI76|H0YI76_HUMAN" 2 915.5025 326.17 93433 4176 2 915.501518 458.7585 "Keratin, type II cytoskeletal 5 OS=Homo sapiens OX=9606 GN=KRT5 PE=1 SV=3" 6.11 1375.7 - 1.35E+07 - - - -1.1229 - 1.626 0.247 - 293.3 1 2 0 -0.001 8 0 0 0 2.21E+08 6.77E+05 - - - 2.3311 0.9998 221125_WJC_METTL3_EV_vs_WT_F07.04177.04177.2 2.91E-05 18-Aug K.QSTETAANVK.E sp|O00268|TAF4_HUMAN 1 1047.5197 1.5 93434 4177 2 1047.519182 524.7671 Transcription initiation factor TFIID subunit 4 OS=Homo sapiens OX=9606 GN=TAF4 PE=1 SV=2 6 1375.7 - 7.19E+06 - - - -0.4496 - 1.901 0.471 - 346.3 1 2 0 -0.0005 10 0 0 0 7.53E+07 5.01E+07 - - - 4.3127 0.9998 221125_WJC_METTL3_EV_vs_WT_F07.04179.04179.2 0.0139 18-Sep K.QSTETAANVK[136.11].E sp|O00268|TAF4_HUMAN 1 1055.5339 1.56 93436 4179 2 1055.533556 528.7742 Transcription initiation factor TFIID subunit 4 OS=Homo sapiens OX=9606 GN=TAF4 PE=1 SV=2 6 1375.8 - 4.72E+06 - - - -0.2814 - 2.129 0.416 - 405 1 2 0 -0.0003 10 0 0 0 7.21E+07 4.63E+07 - - - 4.2227 0.9699 221125_WJC_METTL3_EV_vs_WT_F07.04182.04182.2 2.91 14-May R.KSSTLEVK.D "sp|Q16514|TAF12_HUMAN,tr|A0A804HLG9|A0A804HLG9_HUMAN" 2 890.5073 1.48 93439 4182 2 890.506747 446.2609 Transcription initiation factor TFIID subunit 12 OS=Homo sapiens OX=9606 GN=TAF12 PE=1 SV=1 8.59 1376 - 3.02E+06 - - - -0.6176 - 1.066 0.112 - 92.1 2 2 0 -0.0006 8 0 0 0 2.29E+07 1.55E+07 - - - -0.0737 0.9863 221125_WJC_METTL3_EV_vs_WT_F07.04183.04183.2 1.16 14-May K.K[136.11]IGVNQPK[136.11].R "sp|P78371|TCPB_HUMAN,tr|F8VQ14|F8VQ14_HUMAN,tr|F5GWF6|F5GWF6_HUMAN" 3 898.5571 0.52 93440 4183 2 898.556355 450.2858 T-complex protein 1 subunit beta OS=Homo sapiens OX=9606 GN=CCT2 PE=1 SV=4 10 1376 - 3.72E+06 - - - -0.8302 - 1.261 0.119 - 106.8 2 2 0 -0.0007 8 0 0 0 2.48E+07 4.74E+07 - - - 0.4846 0.9999 221125_WJC_METTL3_EV_vs_WT_F07.04187.04187.2 1.17E-06 13/22 R.AEASPNDTAGAR.T "sp|Q96RK0|CIC_HUMAN,tr|A0A0A0MQR4|A0A0A0MQR4_HUMAN,tr|I3L2J0|I3L2J0_HUMAN,tr|A0A7P0T9K5|A0A7P0T9K5_HUMAN" 4 1158.5265 1.18 93444 4187 2 1158.526486 580.2705 Protein capicua homolog OS=Homo sapiens OX=9606 GN=CIC PE=1 SV=2 4.37 1376.4 - 560008 - - - -0.0371 - 2.355 0.574 - 679.2 1 2 0 0 12 0 0 0 5.11E+06 4.32E+06 - - - 5.5343 0.9996 221125_WJC_METTL3_EV_vs_WT_F07.04190.04190.2 0.000927 18-Aug R.IEESGNDEAR.V "sp|Q8TAQ2|SMRC2_HUMAN,tr|F8VXC8|F8VXC8_HUMAN" 2 1118.484 999 93447 4190 2 1118.485928 560.2493 SWI\SNF complex subunit SMARCC2 OS=Homo sapiens OX=9606 GN=SMARCC2 PE=1 SV=1 4 1376.7 - 297075 - - - 1.7273 - 1.817 0.454 - 211.5 1 2 0 0.0019 10 0 0 0 1.16E+06 0.00E+00 - - - 4.0606 0.9998 221125_WJC_METTL3_EV_vs_WT_F07.04197.04197.2 0.000881 16-Aug R.DMASNEGSR.L sp|P98175|RBM10_HUMAN 1 965.3873 3.22 93452 4197 2 965.387644 483.7009 RNA-binding protein 10 OS=Homo sapiens OX=9606 GN=RBM10 PE=1 SV=3 4.37 1377.5 - 2.49E+06 - - - 0.3998 - 1.56 0.554 - 247.7 1 2 0 0.0004 9 0 0 0 3.16E+07 9.81E+06 - - - 4.4192 0.9997 221125_WJC_METTL3_EV_vs_WT_F07.04199.04199.2 0.00145 16-Aug K.EQQASMEEK[136.11].F sp|P12270|TPR_HUMAN 1 1086.4743 2.46 93454 4199 2 1086.473721 544.2444 Nucleoprotein TPR OS=Homo sapiens OX=9606 GN=TPR PE=1 SV=3 4.25 1377.8 - 897012 - - - -0.5228 - 1.672 0.417 - 347.5 1 2 0 -0.0006 9 0 0 0 2.21E+07 9.01E+06 - - - 3.6079 0.9998 221125_WJC_METTL3_EV_vs_WT_F07.04202.04202.2 0.0108 18-Aug R.MDTEEAR[166.11]PAK[136.11].R "sp|Q9NRX1|PNO1_HUMAN,tr|F8WBJ6|F8WBJ6_HUMAN" 2 1164.5564 1.02 93457 4202 2 1164.555491 583.2855 RNA-binding protein PNO1 OS=Homo sapiens OX=9606 GN=PNO1 PE=1 SV=1 4.68 1378.2 - 236426 - - - -0.7745 - 1.942 0.497 - 268.6 1 2 0 -0.0009 10 0 0 0 4.49E+06 4.41E+06 - - - 4.5642 1 221125_WJC_METTL3_EV_vs_WT_F07.04205.04205.3 3.33E-05 Dec-36 R.MDTEEARPAK.R "sp|Q9NRX1|PNO1_HUMAN,tr|F8WBJ6|F8WBJ6_HUMAN" 2 1146.5339 1.37 93458 4205 3 1146.534122 383.1853 RNA-binding protein PNO1 OS=Homo sapiens OX=9606 GN=PNO1 PE=1 SV=1 4.68 1378.6 - 2.71E+06 - - - 0.1736 - 2.09 0.477 - 209.1 1 2 0 0.0002 10 0 0 0 4.34E+07 3.16E+07 - - - 6.0109 0.9999 221125_WJC_METTL3_EV_vs_WT_F07.04206.04206.2 0.000387 13/20 K.SPAVKPAAAPK.Q "sp|Q14978|NOLC1_HUMAN,tr|A0A0A0MRM9|A0A0A0MRM9_HUMAN" 2 1035.6077 2.1 93459 4206 2 1035.607495 518.8111 Nucleolar and coiled-body phosphoprotein 1 OS=Homo sapiens OX=9606 GN=NOLC1 PE=1 SV=2 10 1378.6 - 1.92E+06 - - - -0.1786 - 2.414 0.468 - 738.1 1 2 0 -0.0002 11 0 0 0 2.33E+08 1.11E+08 - - - 4.8817 0.9998 221125_WJC_METTL3_EV_vs_WT_F07.04208.04208.2 6.35E-05 16-Nov R.ADHGEPIGR[166.11].G "sp|P08238|HS90B_HUMAN,sp|Q58FF7|H90B3_HUMAN" 2 960.4653 0.81 93461 4208 2 960.465934 481.2399 Heat shock protein HSP 90-beta OS=Homo sapiens OX=9606 GN=HSP90AB1 PE=1 SV=4 5.32 1378.8 - 1.57E+06 - - - 0.6986 - 2.129 0.43 - 478.2 1 2 0 0.0007 9 0 0 0 2.69E+08 3.33E+08 - - - 4.4029 0.986 221125_WJC_METTL3_EV_vs_WT_F07.04211.04211.2 0.321 16-Jul K.NSNGQELEK[136.11].T sp|Q7Z6Z7|HUWE1_HUMAN 1 1025.4869 0.56 93464 4211 2 1025.486892 513.7507 E3 ubiquitin-protein ligase HUWE1 OS=Homo sapiens OX=9606 GN=HUWE1 PE=1 SV=3 4.53 1379 - 1.10E+06 - - - -0.0107 - 1.291 0.083 - 192.7 1 2 0 0 9 0 0 0 8.22E+06 1.47E+07 - - - 0.393 0.8769 221125_WJC_METTL3_EV_vs_WT_F07.04212.04212.2 0.143 14-May E.K[136.11]ELSSTVK[136.11].L sp|P16383|GCFC2_HUMAN 1 906.5357 1.48 93465 4212 2 906.535994 454.2751 Intron Large complex component GCFC2 OS=Homo sapiens OX=9606 GN=GCFC2 PE=1 SV=2 8.59 1379.1 - 667464 - - - 0.3276 - 1.324 0.246 - 114.7 1 1 0 0.0003 8 0 0 0 2.29E+07 1.55E+07 - - - 1.7043 0.7832 221125_WJC_METTL3_EV_vs_WT_F07.04214.04214.2 11.8 16-May R.SSSLPPSNR.K "sp|Q99550|MPP9_HUMAN,tr|U3KQJ0|U3KQJ0_HUMAN,tr|A0A0A0MTP3|A0A0A0MTP3_HUMAN,tr|J3KNE4|J3KNE4_HUMAN,tr|H0YG46|H0YG46_HUMAN" 5 943.4723 1.65 93467 4214 2 943.473856 472.7434 M-phase phosphoprotein 9 OS=Homo sapiens OX=9606 GN=MPHOSPH9 PE=1 SV=4 9.47 1379.3 - 435977 - - - 1.6397 - 1.083 0 - 114.8 6 2 0 0.0015 9 0 0 0 4.31E+06 2.61E+06 - - - -1.0764 0.9996 221125_WJC_METTL3_EV_vs_WT_F07.04216.04216.2 0.000136 18-Jul R.MDTEEARPAK.R "sp|Q9NRX1|PNO1_HUMAN,tr|F8WBJ6|F8WBJ6_HUMAN" 2 1146.5339 1.02 93469 4216 2 1146.531848 574.2742 RNA-binding protein PNO1 OS=Homo sapiens OX=9606 GN=PNO1 PE=1 SV=1 4.68 1379.6 - 292233 - - - -1.8098 - 1.719 0.47 - 205.8 1 2 0 -0.0021 10 0 0 0 4.49E+06 4.41E+06 - - - 4.0239 0.9896 221125_WJC_METTL3_EV_vs_WT_F07.04220.04220.2 0.535 12-Sep R.SKEITVR.G "sp|P17844|DDX5_HUMAN,tr|J3QR02|J3QR02_HUMAN,tr|A0A7I2V507|A0A7I2V507_HUMAN,tr|J3KTA4|J3KTA4_HUMAN,tr|J3KTQ4|J3KTQ4_HUMAN,tr|A0A7I2V2S0|A0A7I2V2S0_HUMAN,tr|J3QRQ7|J3QRQ7_HUMAN" 7 831.4814 1.61 93471 4220 2 831.481333 416.748 Probable ATP-dependent RNA helicase DDX5 OS=Homo sapiens OX=9606 GN=DDX5 PE=1 SV=1 8.46 1380 - 4.13E+06 - - - -0.101 - 1.831 0.198 - 328.6 1 2 1 -0.0001 7 0 0 0 4.17E+08 2.60E+08 - - - 2.4199 0.9994 221125_WJC_METTL3_EV_vs_WT_F07.04221.04221.2 0.000868 14-Aug K.NQDGEINR.N "sp|Q8ND24|RN214_HUMAN,tr|E9PN76|E9PN76_HUMAN" 2 944.4312 1.88 93472 4221 2 944.429666 473.2229 RING finger protein 214 OS=Homo sapiens OX=9606 GN=RNF214 PE=1 SV=2 4.37 1380.1 - 1.98E+06 - - - -1.5946 - 1.585 0.404 - 414 1 2 0 -0.0015 8 0 0 0 7.95E+07 4.24E+07 - - - 3.4136 0.9997 221125_WJC_METTL3_EV_vs_WT_F07.04222.04222.2 0.00227 18-Dec R.SAQPASAEPR.Q sp|Q9Y490|TLN1_HUMAN 1 1012.4938 1.58 93473 4222 2 1012.493828 507.2542 Talin-1 OS=Homo sapiens OX=9606 GN=TLN1 PE=1 SV=3 5.72 1380.1 - 1.78E+06 - - - 0.0553 - 1.927 0.361 - 471.3 1 2 0 0.0001 10 0 0 0 3.63E+07 2.30E+07 - - - 3.5383 0.9139 221125_WJC_METTL3_EV_vs_WT_F07.04224.04224.2 8.36 12-May K.K[136.11]ALPPEK[136.11].K "sp|Q00839|HNRPU_HUMAN,tr|A0A1W2PQL0|A0A1W2PQL0_HUMAN,tr|A0A1W2PPL4|A0A1W2PPL4_HUMAN,tr|A0A087WZF3|A0A087WZF3_HUMAN,tr|Q5RI18|Q5RI18_HUMAN,tr|A0A1W2PP35|A0A1W2PP35_HUMAN,tr|A0A1W2PPS1|A0A1W2PPS1_HUMAN,tr|A0A1W2PPH7|A0A1W2PPH7_HUMAN,tr|A0A1W2PQD4|A0A1W2PQD4_HUMAN,tr|A0A1W2PP34|A0A1W2PP34_HUMAN,tr|A0A1X7SBS1|A0A1X7SBS1_HUMAN" 11 797.4982 1.19 93475 4224 2 797.497047 399.7564 Heterogeneous nuclear ribonucleoprotein U OS=Homo sapiens OX=9606 GN=HNRNPU PE=1 SV=6 8.59 1380.3 - 433042 - - - -1.4332 - 0.999 0.056 - 113.1 1 2 0 -0.0011 7 0 0 0 1.34E+07 1.12E+07 - - - -0.5489 0.9999 221125_WJC_METTL3_EV_vs_WT_F07.04228.04228.2 0.000169 13/20 K.SPAVK[136.11]PAAAPK[136.11].Q "sp|Q14978|NOLC1_HUMAN,tr|A0A0A0MRM9|A0A0A0MRM9_HUMAN" 2 1051.6361 2.11 93477 4228 2 1051.635875 526.8253 Nucleolar and coiled-body phosphoprotein 1 OS=Homo sapiens OX=9606 GN=NOLC1 PE=1 SV=2 10 1380.8 - 4.00E+06 - - - -0.1949 - 2.349 0.487 - 748.5 1 2 0 -0.0002 11 0 0 0 2.33E+08 1.11E+08 - - - 4.9482 0.9995 221125_WJC_METTL3_EV_vs_WT_F07.04229.04229.2 0.00157 16-Jul K.SVR[166.11]PGASYK[136.11].R "sp|Q8NEY8|PPHLN_HUMAN,tr|B7Z8L1|B7Z8L1_HUMAN,tr|F8W0Q9|F8W0Q9_HUMAN" 3 981.5362 1.64 93478 4229 2 981.536038 491.7754 Periphilin-1 OS=Homo sapiens OX=9606 GN=PPHLN1 PE=1 SV=2 9.99 1380.8 - 1.96E+06 - - - -0.216 - 1.623 0.337 - 153.2 1 2 0 -0.0002 9 0 0 0 5.50E+07 3.35E+07 - - - 2.9311 0.9995 221125_WJC_METTL3_EV_vs_WT_F07.04230.04230.2 0.00314 16-Aug K.EQQASMEEK.F sp|P12270|TPR_HUMAN 1 1078.4601 2.46 93479 4230 2 1078.459932 540.2373 Nucleoprotein TPR OS=Homo sapiens OX=9606 GN=TPR PE=1 SV=3 4.25 1380.9 - 1.56E+06 - - - -0.1456 - 1.287 0.429 - 242.2 1 2 0 -0.0002 9 0 0 0 2.21E+07 9.01E+06 - - - 2.9395 0.9959 221125_WJC_METTL3_EV_vs_WT_F07.04231.04231.2 0.000131 20-Nov K.TGQSADSGTIK[136.11].A "sp|Q9HD26|GOPC_HUMAN,tr|F5H1Y4|F5H1Y4_HUMAN" 2 1071.5288 1.22 93480 4231 2 1071.522693 536.7717 Golgi-associated PDZ and coiled-coil motif-containing protein OS=Homo sapiens OX=9606 GN=GOPC PE=1 SV=1 5.5 1381 - 1.33E+06 - - - -5.6695 - 1.997 0.511 - 420.6 1 2 0 -0.0061 11 0 0 0 1.43E+07 1.17E+07 - - - 4.6844 0.9928 221125_WJC_METTL3_EV_vs_WT_F07.04234.04234.2 0.852 14-Jul R.FNDGSDEK.K "sp|P25705|ATPA_HUMAN,tr|K7EK77|K7EK77_HUMAN,tr|K7ENJ4|K7ENJ4_HUMAN" 3 910.3668 0.83 93483 4234 2 910.366828 456.1907 "ATP synthase subunit alpha, mitochondrial OS=Homo sapiens OX=9606 GN=ATP5F1A PE=1 SV=1" 4.03 1381.3 - 596860 - - - -0.0143 - 1.203 0.168 - 105 1 2 0 0 8 0 0 0 9.86E+06 1.19E+07 - - - 0.8392 0.9999 221125_WJC_METTL3_EV_vs_WT_F07.04235.04235.2 3.14E-05 22-Oct K.VGSC[160.03]AEAGEGSR[166.11].G "sp|Q96PV7|F193B_HUMAN,tr|H0YCX2|H0YCX2_HUMAN,tr|H0Y9G1|H0Y9G1_HUMAN" 3 1188.5069 0.52 93484 4235 2 1188.50631 595.2607 Protein FAM193B OS=Homo sapiens OX=9606 GN=FAM193B PE=1 SV=3 4.53 1381.3 - 465040 - - - -0.4712 - 2.199 0.563 - 380.9 1 2 0 -0.0006 12 0 0 0 5.45E+06 1.05E+07 - - - 5.2725 0.9966 221125_WJC_METTL3_EV_vs_WT_F07.04242.04242.2 0.272 12-Jul R.DQVIGHR.K "sp|Q8IX01|SUGP2_HUMAN,tr|M0R216|M0R216_HUMAN,tr|M0R2Z9|M0R2Z9_HUMAN,tr|M0R3F6|M0R3F6_HUMAN" 4 823.4301 1.21 93489 4242 2 823.429413 412.7223 SURP and G-patch domain-containing protein 2 OS=Homo sapiens OX=9606 GN=SUGP2 PE=1 SV=2 6.74 1382 - 1.93E+06 - - - -0.7736 - 1.483 0.157 - 365.8 1 2 0 -0.0006 7 0 0 0 2.84E+07 2.34E+07 - - - 1.449 0.8175 221125_WJC_METTL3_EV_vs_WT_F07.04243.04243.2 7.23 16-Jun R.SVSC[160.03]DNVSK[136.11].V "sp|Q96CB8|INT12_HUMAN,tr|A0A087WXN4|A0A087WXN4_HUMAN" 2 1002.4532 0.75 93490 4243 2 1002.454693 502.2339 Integrator complex subunit 12 OS=Homo sapiens OX=9606 GN=INTS12 PE=1 SV=1 5.55 1382.1 - 1.17E+06 - - - 1.5292 - 0.945 0.019 - 107.3 1 2 0 0.0015 9 0 0 0 3.49E+07 4.63E+07 - - - -0.9828 0.9993 221125_WJC_METTL3_EV_vs_WT_F07.04244.04244.2 0.00715 20-Sep K.TEPGPAADSQK.L sp|Q96K30|RITA1_HUMAN 1 1099.5146 1.93 93491 4244 2 1099.514389 550.7646 RBPJ-interacting and tubulin-associated protein 1 OS=Homo sapiens OX=9606 GN=RITA1 PE=1 SV=1 4.37 1382.2 - 313754 - - - -0.1628 - 1.498 0.349 - 178.9 1 2 0 -0.0002 11 0 0 0 6.34E+06 3.29E+06 - - - 2.7119 0.9948 221125_WJC_METTL3_EV_vs_WT_F07.04245.04245.2 0.259 18-Jul K.AK[136.11]PLGTVQQK[136.11].R "sp|Q9H583|HEAT1_HUMAN,tr|Q5T3Q7|Q5T3Q7_HUMAN" 2 1084.6575 1.23 93492 4245 2 1084.656108 543.336 HEAT repeat-containing protein 1 OS=Homo sapiens OX=9606 GN=HEATR1 PE=1 SV=3 10 1382.3 - 275812 - - - -1.3239 - 1.313 0.205 - 108.7 1 2 0 -0.0014 10 0 0 0 1.34E+07 1.09E+07 - - - 1.3148 0.9985 221125_WJC_METTL3_EV_vs_WT_F07.04250.04250.2 0.619 14-Jun K.K[136.11]DESLVSK[136.11].A sp|Q8NFH5|NUP35_HUMAN 1 920.515 1.75 93495 4250 2 920.515315 461.2648 Nucleoporin NUP35 OS=Homo sapiens OX=9606 GN=NUP35 PE=1 SV=1 6.07 1382.9 - 1.03E+06 - - - 0.3835 - 1.559 0.228 - 113.9 1 2 0 0.0004 8 0 0 0 2.01E+08 1.15E+08 - - - 2.0641 0.9958 221125_WJC_METTL3_EV_vs_WT_F07.04251.04251.2 0.0148 14-Jun K.YQEDC[160.03]QAR[166.11].S "sp|Q6ZU65|UBN2_HUMAN,tr|H7C4P8|H7C4P8_HUMAN" 2 1078.4377 1.13 93496 4251 2 1078.434225 540.2261 Ubinuclein-2 OS=Homo sapiens OX=9606 GN=UBN2 PE=1 SV=2 4.37 1383 - 629101 - - - -3.2482 - 1.325 0.364 - 98.4 1 2 0 -0.0035 8 0 0 0 1.56E+07 1.38E+07 - - - 2.5771 0.9993 221125_WJC_METTL3_EV_vs_WT_F07.04258.04258.2 4.03E-06 22-Oct R.APEAADEGDAQK.G "sp|P17481|HXB8_HUMAN,tr|I3L3R1|I3L3R1_HUMAN,tr|I3L383|I3L383_HUMAN" 3 1200.5259 1.33 93500 4258 2 1200.521742 601.2702 Homeobox protein Hox-B8 OS=Homo sapiens OX=9606 GN=HOXB8 PE=1 SV=2 3.92 1383.9 - 128753 - - - -3.431 - 2.043 0.552 - 226.2 1 2 0 -0.0041 12 0 0 0 1.90E+06 1.43E+06 - - - 4.9965 0.9994 221125_WJC_METTL3_EV_vs_WT_F07.04259.04259.2 0.000535 22-Sep K.GSETPGATPGSK[136.11].L sp|O75533|SF3B1_HUMAN 1 1095.5288 1.67 93501 4259 2 1095.527786 548.7717 Splicing factor 3B subunit 1 OS=Homo sapiens OX=9606 GN=SF3B1 PE=1 SV=3 6 1384 - 270723 - - - -0.8964 - 1.652 0.356 - 216.4 1 2 0 -0.001 12 0 0 0 2.89E+07 1.73E+07 - - - 2.9909 0.9801 221125_WJC_METTL3_EV_vs_WT_F07.04264.04264.2 0.00389 22-Oct K.GSETPGATPGSK.L sp|O75533|SF3B1_HUMAN 1 1087.5146 1.6 93504 4264 2 1088.518405 544.7646 Splicing factor 3B subunit 1 OS=Homo sapiens OX=9606 GN=SF3B1 PE=1 SV=3 6 1384.6 - 451625 - - - 923.0561 - 1.827 0.379 - 293.6 1 2 0 1.0038 12 0 0 0 2.93E+07 1.83E+07 - - - 3.1108 0.9684 221125_WJC_METTL3_EV_vs_WT_F07.04269.04269.2 0.00587 16-Jul K.K[136.11]GAVEC[160.03]C[160.03]PN.C sp|P31689|DNJA1_HUMAN 1 1041.4463 0.44 93507 4269 2 1041.446349 521.7304 DnaJ homolog subfamily A member 1 OS=Homo sapiens OX=9606 GN=DNAJA1 PE=1 SV=2 5.99 1385.2 - 1.32E+06 - - - 0.0461 - 1.291 0.428 - 163.6 1 1 0 0 9 0 0 0 1.37E+07 3.09E+07 - - - 2.9411 0.9995 221125_WJC_METTL3_EV_vs_WT_F07.04274.04274.2 0.000106 18-Sep R.EATVNGEENR.A "sp|O60907|TBL1X_HUMAN,tr|A0A804HJZ5|A0A804HJZ5_HUMAN,tr|A0A2R8YFW3|A0A2R8YFW3_HUMAN" 3 1117.5 2.88 93510 4274 2 1117.502449 559.7573 F-box-like\WD repeat-containing protein TBL1X OS=Homo sapiens OX=9606 GN=TBL1X PE=1 SV=3 4.25 1385.8 - 1.36E+06 - - - 2.2094 - 1.944 0.458 - 326.7 1 2 0 0.0025 10 0 0 0 4.24E+07 1.47E+07 - - - 4.2785 0.9998 221125_WJC_METTL3_EV_vs_WT_F07.04278.04278.2 2.00E-05 24-Oct K.LGNSGASPSSAGK[136.11].- sp|Q8IWI9|MGAP_HUMAN 1 1139.5662 1.59 93514 4278 2 1139.567618 570.7904 MAX gene-associated protein OS=Homo sapiens OX=9606 GN=MGA PE=1 SV=4 8.75 1386.3 - 236186 - - - 1.2303 - 2.112 0.465 - 284.6 1 2 0 0.0014 13 0 0 0 1.96E+07 1.23E+07 - - - 4.3939 0.9586 221125_WJC_METTL3_EV_vs_WT_F07.04282.04282.2 0.00543 12-Jun V.PEPC[160.03]HPK.V "sp|P35321|SPR1A_HUMAN,sp|P22528|SPR1B_HUMAN" 2 863.396 21.5 93516 4282 2 863.395926 432.7053 Cornifin-A OS=Homo sapiens OX=9606 GN=SPRR1A PE=1 SV=2 7.12 1386.8 - 2.79E+06 - - - -0.0544 - 1.21 0.409 - 142.5 1 1 0 0 7 0 0 0 7.04E+08 3.27E+07 - - - 2.6659 0.9966 221125_WJC_METTL3_EV_vs_WT_F07.04292.04292.3 0.106 Oct-32 R.LK[136.11]QENPNMR[166.11].L sp|Q96CT7|CC124_HUMAN 1 1146.5934 0.001 93524 4292 3 1146.59341 383.2051 Coiled-coil domain-containing protein 124 OS=Homo sapiens OX=9606 GN=CCDC124 PE=1 SV=1 8.75 1387.8 - 3.65E+06 - - - -0.0323 - 1.988 0.262 - 206.5 1 2 1 0 9 0 0 0 0.00E+00 8.27E+07 - - - 3.5319 0.8539 221125_WJC_METTL3_EV_vs_WT_F07.04293.04293.2 0.343 12-Jul R.SK[136.11]EITVR[166.11].G "sp|P17844|DDX5_HUMAN,tr|J3QR02|J3QR02_HUMAN,tr|A0A7I2V507|A0A7I2V507_HUMAN,tr|J3KTA4|J3KTA4_HUMAN,tr|J3KTQ4|J3KTQ4_HUMAN,tr|A0A7I2V2S0|A0A7I2V2S0_HUMAN,tr|J3QRQ7|J3QRQ7_HUMAN" 7 849.5039 1.6 93525 4293 2 849.503818 425.7592 Probable ATP-dependent RNA helicase DDX5 OS=Homo sapiens OX=9606 GN=DDX5 PE=1 SV=1 8.46 1387.9 - 1.86E+06 - - - -0.0812 - 1.348 0.048 - 185 1 2 1 -0.0001 7 0 0 0 4.16E+08 2.60E+08 - - - 0.3417 0.9836 221125_WJC_METTL3_EV_vs_WT_F07.04294.04294.2 4.88 14-Aug R.KLSPTEPK.N sp|O14828|SCAM3_HUMAN 1 898.5124 1.44 93526 4294 2 898.51244 450.2635 Secretory carrier-associated membrane protein 3 OS=Homo sapiens OX=9606 GN=SCAMP3 PE=1 SV=3 8.59 1387.9 - 2.32E+06 - - - 0.0634 - 1.513 0 - 240.1 1 2 0 0.0001 8 0 0 0 4.82E+07 3.35E+07 - - - 0.2899 0.9849 221125_WJC_METTL3_EV_vs_WT_F07.04298.04298.2 1.54 14-Jul R.K[136.11]LSPTEPK[136.11].N sp|O14828|SCAM3_HUMAN 1 914.5408 1.37 93528 4298 2 914.540539 458.2777 Secretory carrier-associated membrane protein 3 OS=Homo sapiens OX=9606 GN=SCAMP3 PE=1 SV=3 8.59 1388.4 - 2.30E+06 - - - -0.2668 - 1.538 0 - 190.8 1 2 0 -0.0002 8 0 0 0 4.55E+07 3.32E+07 - - - 0.3392 0.9992 221125_WJC_METTL3_EV_vs_WT_F07.04300.04300.2 0.17 14-Aug K.ESLHEVSK.S "sp|O43615|TIM44_HUMAN,tr|M0QXU7|M0QXU7_HUMAN" 2 927.4662 1.01 93530 4300 2 927.465837 464.7404 Mitochondrial import inner membrane translocase subunit TIM44 OS=Homo sapiens OX=9606 GN=TIMM44 PE=1 SV=2 5.4 1388.6 - 1.30E+06 - - - -0.3493 - 1.507 0.316 - 265.2 1 2 0 -0.0003 8 0 0 0 1.69E+08 1.67E+08 - - - 2.6118 0.9999 221125_WJC_METTL3_EV_vs_WT_F07.04301.04301.2 3.75E-06 18-Oct K.TGEITASSNK.S "sp|Q8TAT6|NPL4_HUMAN,tr|I3L4U9|I3L4U9_HUMAN,tr|A0A0D9SFI9|A0A0D9SFI9_HUMAN" 3 1006.4931 0.62 93531 4301 2 1006.492619 504.2538 Nuclear protein localization protein 4 homolog OS=Homo sapiens OX=9606 GN=NPLOC4 PE=1 SV=3 5.66 1388.7 - 1.11E+06 - - - -0.4819 - 2.073 0.47 - 534.3 1 2 0 -0.0005 10 0 0 0 1.53E+07 2.47E+07 - - - 4.5471 0.984 221125_WJC_METTL3_EV_vs_WT_F07.04302.04302.2 0.0244 16-Aug R.LK[136.11]QENPNMR[166.11].L sp|Q96CT7|CC124_HUMAN 1 1146.5934 1.73 93532 4302 2 1146.597 574.304 Coiled-coil domain-containing protein 124 OS=Homo sapiens OX=9606 GN=CCDC124 PE=1 SV=1 8.75 1388.8 - 563567 - - - 3.0987 - 1.827 0.381 - 176.3 1 2 1 0.0036 9 0 0 0 1.63E+07 9.42E+06 - - - 3.5975 0.9996 221125_WJC_METTL3_EV_vs_WT_F07.04307.04307.2 0.0266 14-Oct K.ESLHEVSK[136.11].S "sp|O43615|TIM44_HUMAN,tr|M0QXU7|M0QXU7_HUMAN" 2 935.4804 1.01 93535 4307 2 935.480216 468.7475 Mitochondrial import inner membrane translocase subunit TIM44 OS=Homo sapiens OX=9606 GN=TIMM44 PE=1 SV=2 5.4 1389.4 - 3.83E+06 - - - -0.155 - 1.754 0.354 - 464.6 1 2 0 -0.0001 8 0 0 0 1.69E+08 1.66E+08 - - - 3.3503 0.9975 221125_WJC_METTL3_EV_vs_WT_F07.04309.04309.2 0.0331 16-Aug R.TAEEPPQEK[136.11].A "sp|O43719|HTSF1_HUMAN,tr|Q5H919|Q5H919_HUMAN,tr|Q5H918|Q5H918_HUMAN" 3 1035.4964 1.13 93537 4309 2 1035.495841 518.7555 HIV Tat-specific factor 1 OS=Homo sapiens OX=9606 GN=HTATSF1 PE=1 SV=1 4.25 1389.5 - 1.48E+06 - - - -0.5447 - 1.248 0.266 - 224.9 1 2 0 -0.0006 9 0 0 0 4.01E+07 3.55E+07 - - - 1.6464 0.9999 221125_WJC_METTL3_EV_vs_WT_F07.04310.04310.2 0.000121 24-Dec K.LGNSGASPSSAGK.- sp|Q8IWI9|MGAP_HUMAN 1 1131.552 1.37 93538 4310 2 1131.551705 566.7833 MAX gene-associated protein OS=Homo sapiens OX=9606 GN=MGA PE=1 SV=4 8.75 1389.6 - 890867 - - - -0.2748 - 2.067 0.507 - 381.4 1 2 0 -0.0003 13 0 0 0 1.58E+07 1.16E+07 - - - 4.6492 0.9878 221125_WJC_METTL3_EV_vs_WT_F07.04311.04311.2 1.88E-05 20-Oct Q.AGQC[160.03]GNQIGAK[136.11].F "sp|P04350|TBB4A_HUMAN,sp|Q9BVA1|TBB2B_HUMAN,sp|P07437|TBB5_HUMAN,sp|Q13509|TBB3_HUMAN,sp|Q13885|TBB2A_HUMAN,sp|P68371|TBB4B_HUMAN,tr|M0R2D3|M0R2D3_HUMAN,tr|G3V3W7|G3V3W7_HUMAN,tr|M0R2T4|M0R2T4_HUMAN,tr|G3V3R4|G3V3R4_HUMAN,tr|M0R042|M0R042_HUMAN,tr|M0QY85|M0QY85_HUMAN,tr|M0QZL7|M0QZL7_HUMAN,tr|G3V5W4|G3V5W4_HUMAN,tr|M0R0X0|M0R0X0_HUMAN,tr|M0QYM7|M0QYM7_HUMAN,tr|G3V4U2|G3V4U2_HUMAN,tr|M0R278|M0R278_HUMAN,tr|M0QY37|M0QY37_HUMAN,tr|G3V2R8|G3V2R8_HUMAN,tr|G3V3J6|G3V3J6_HUMAN,tr|M0QX14|M0QX14_HUMAN,tr|G3V2N6|G3V2N6_HUMAN" 23 1110.5331 1.81 93539 4311 2 1110.533036 556.2738 Tubulin beta-4A chain OS=Homo sapiens OX=9606 GN=TUBB4A PE=1 SV=2 8.27 1389.7 - 743508 - - - -0.0954 - 1.81 0.458 - 314.2 1 1 0 -0.0001 11 0 0 0 1.64E+07 9.06E+06 - - - 4.0288 0.9891 221125_WJC_METTL3_EV_vs_WT_F07.04312.04312.2 2.43E-05 20-Oct Q.AGQC[160.03]GNQIGAK.F "sp|P04350|TBB4A_HUMAN,sp|Q9BVA1|TBB2B_HUMAN,sp|P07437|TBB5_HUMAN,sp|Q13509|TBB3_HUMAN,sp|Q13885|TBB2A_HUMAN,sp|P68371|TBB4B_HUMAN,tr|M0R2D3|M0R2D3_HUMAN,tr|G3V3W7|G3V3W7_HUMAN,tr|M0R2T4|M0R2T4_HUMAN,tr|G3V3R4|G3V3R4_HUMAN,tr|M0R042|M0R042_HUMAN,tr|M0QY85|M0QY85_HUMAN,tr|M0QZL7|M0QZL7_HUMAN,tr|G3V5W4|G3V5W4_HUMAN,tr|M0R0X0|M0R0X0_HUMAN,tr|M0QYM7|M0QYM7_HUMAN,tr|G3V4U2|G3V4U2_HUMAN,tr|M0R278|M0R278_HUMAN,tr|M0QY37|M0QY37_HUMAN,tr|G3V2R8|G3V2R8_HUMAN,tr|G3V3J6|G3V3J6_HUMAN,tr|M0QX14|M0QX14_HUMAN,tr|G3V2N6|G3V2N6_HUMAN" 23 1102.5189 2.34 93540 4312 2 1102.517695 552.2667 Tubulin beta-4A chain OS=Homo sapiens OX=9606 GN=TUBB4A PE=1 SV=2 8.27 1389.8 - 528672 - - - -1.131 - 1.929 0.507 - 434.9 1 1 0 -0.0012 11 0 0 0 2.13E+07 9.13E+06 - - - 4.5627 0.9976 221125_WJC_METTL3_EV_vs_WT_F07.04316.04316.2 0.158 14-Aug K.KDESLVSK.A sp|Q8NFH5|NUP35_HUMAN 1 904.4866 1.75 93543 4316 2 904.486463 453.2506 Nucleoporin NUP35 OS=Homo sapiens OX=9606 GN=NUP35 PE=1 SV=1 6.07 1390.2 - 4.24E+06 - - - -0.1095 - 1.642 0.149 - 211.3 1 2 0 -0.0001 8 0 0 0 2.01E+08 1.15E+08 - - - 1.6371 0.9999 221125_WJC_METTL3_EV_vs_WT_F07.04320.04320.2 0.00289 12-Oct R.RC[160.03]DELTR.K "sp|P17844|DDX5_HUMAN,tr|A0A7I2V5F5|A0A7I2V5F5_HUMAN,tr|J3QSF1|J3QSF1_HUMAN,tr|A0A7I2V507|A0A7I2V507_HUMAN,tr|J3KTA4|J3KTA4_HUMAN,tr|A0A0G2JLI4|A0A0G2JLI4_HUMAN,tr|A0A7I2V2S0|A0A7I2V2S0_HUMAN" 7 948.4447 1.6 93546 4320 2 948.444624 475.2296 Probable ATP-dependent RNA helicase DDX5 OS=Homo sapiens OX=9606 GN=DDX5 PE=1 SV=1 6.06 1390.6 - 1.06E+07 - - - -0.0949 - 1.995 0.447 - 292.8 1 2 0 -0.0001 7 0 0 0 1.47E+08 9.19E+07 - - - 4.5309 0.9998 221125_WJC_METTL3_EV_vs_WT_F07.04321.04321.2 0.000895 12-Oct R.R[166.11]C[160.03]DELTR[166.11].K "sp|P17844|DDX5_HUMAN,tr|A0A7I2V5F5|A0A7I2V5F5_HUMAN,tr|J3QSF1|J3QSF1_HUMAN,tr|A0A7I2V507|A0A7I2V507_HUMAN,tr|J3KTA4|J3KTA4_HUMAN,tr|A0A0G2JLI4|A0A0G2JLI4_HUMAN,tr|A0A7I2V2S0|A0A7I2V2S0_HUMAN" 7 968.4613 2.88 93547 4321 2 968.461493 485.2379 Probable ATP-dependent RNA helicase DDX5 OS=Homo sapiens OX=9606 GN=DDX5 PE=1 SV=1 6.06 1390.6 - 8.56E+06 - - - 0.2468 - 1.87 0.389 - 315.3 1 2 0 0.0002 7 0 0 0 3.25E+08 1.13E+08 - - - 3.8974 0.7905 221125_WJC_METTL3_EV_vs_WT_F07.04322.04322.2 1.94 12-Aug E.SLHEVSK[136.11].S "sp|O43615|TIM44_HUMAN,tr|M0QXU7|M0QXU7_HUMAN" 2 806.4378 1.98 93548 4322 2 806.437734 404.2262 Mitochondrial import inner membrane translocase subunit TIM44 OS=Homo sapiens OX=9606 GN=TIMM44 PE=1 SV=2 6.47 1390.7 - 2.54E+06 - - - -0.0422 - 1.453 0.131 - 270 1 1 0 0 7 0 0 0 9.80E+07 4.95E+07 - - - 1.1924 0.9986 221125_WJC_METTL3_EV_vs_WT_F07.04325.04325.2 1.55 13/16 R.SVVQQQQTR[166.11].L "sp|Q9H4P4|RNF41_HUMAN,tr|F8VVY2|F8VVY2_HUMAN,tr|F8VSP7|F8VSP7_HUMAN,tr|F8VSB6|F8VSB6_HUMAN,tr|F8VNZ6|F8VNZ6_HUMAN" 5 1082.5708 0.49 93551 4325 2 1082.572555 542.2927 E3 ubiquitin-protein ligase NRDP1 OS=Homo sapiens OX=9606 GN=RNF41 PE=1 SV=2 9.47 1390.9 - 1.06E+06 - - - 1.6295 - 1.884 0.238 - 1019 1 2 0 0.0018 9 0 0 0 5.60E+06 1.15E+07 - - - 2.6308 0.9989 221125_WJC_METTL3_EV_vs_WT_F07.04331.04331.2 0.000214 14-Sep R.HAIPSAER.G sp|Q92615|LAR4B_HUMAN 1 879.4563 1.23 93555 4331 2 879.454841 440.7354 La-related protein 4B OS=Homo sapiens OX=9606 GN=LARP4B PE=1 SV=3 6.75 1391.7 - 5.74E+06 - - - -1.6192 - 1.767 0.272 - 385.8 1 2 0 -0.0014 8 0 0 0 1.82E+09 1.48E+09 - - - 2.7665 0.9969 221125_WJC_METTL3_EV_vs_WT_F07.04333.04333.2 0.0099 14-Jul K.SGNFGGSR.N "sp|P22626|ROA2_HUMAN,tr|A0A024RA28|A0A024RA28_HUMAN,tr|A0A7I2V4N1|A0A7I2V4N1_HUMAN,tr|A0A7I2V4I6|A0A7I2V4I6_HUMAN,tr|A0A7I2V323|A0A7I2V323_HUMAN,tr|A0A7I2V3P1|A0A7I2V3P1_HUMAN,tr|A0A7I2V3P7|A0A7I2V3P7_HUMAN" 7 780.3515 1.54 93557 4333 2 780.351362 391.183 Heterogeneous nuclear ribonucleoproteins A2\B1 OS=Homo sapiens OX=9606 GN=HNRNPA2B1 PE=1 SV=2 9.47 1391.8 - 3.19E+06 - - - -0.132 - 1.53 0.152 - 267.1 1 2 0 -0.0001 8 0 0 0 5.25E+07 3.41E+07 - - - 1.4462 0.9989 221125_WJC_METTL3_EV_vs_WT_F07.04334.04334.2 0.0588 14-Jul R.HASPEDIK[136.11].K "sp|O75190|DNJB6_HUMAN,tr|C9JDX6|C9JDX6_HUMAN,tr|C9JN01|C9JN01_HUMAN,tr|E9PH18|E9PH18_HUMAN,tr|A0A0J9YX62|A0A0J9YX62_HUMAN,tr|C9JB42|C9JB42_HUMAN,tr|C9JDR7|C9JDR7_HUMAN,tr|C9J2P2|C9J2P2_HUMAN,tr|C9J2C4|C9J2C4_HUMAN,tr|F8WCZ4|F8WCZ4_HUMAN" 10 903.4541 1 93558 4334 2 903.455298 452.7343 DnaJ homolog subfamily B member 6 OS=Homo sapiens OX=9606 GN=DNAJB6 PE=1 SV=2 5.32 1391.8 - 2.12E+06 - - - 1.2751 - 1.552 0.316 - 206.2 1 2 0 0.0012 8 0 0 0 9.88E+07 9.87E+07 - - - 2.7003 0.9991 221125_WJC_METTL3_EV_vs_WT_F07.04335.04335.2 0.0253 14-Aug R.QNEINNPK.F sp|Q15459|SF3A1_HUMAN 1 955.4723 0.46 93559 4335 2 955.472273 478.7434 Splicing factor 3A subunit 1 OS=Homo sapiens OX=9606 GN=SF3A1 PE=1 SV=1 6 1391.9 - 1.65E+06 - - - -0.0377 - 1.368 0.339 - 250.4 1 2 0 0 8 0 0 0 1.20E+08 2.59E+08 - - - 2.4899 0.9976 221125_WJC_METTL3_EV_vs_WT_F07.04342.04342.2 2.12 14-Aug R.HAIPSAER[166.11].G sp|Q92615|LAR4B_HUMAN 1 889.4645 1.23 93564 4342 2 889.464555 445.7395 La-related protein 4B OS=Homo sapiens OX=9606 GN=LARP4B PE=1 SV=3 6.75 1392.7 - 2.01E+07 - - - 0.0225 - 1.527 0.182 - 267.6 1 2 0 0 8 0 0 0 1.82E+09 1.48E+09 - - - 1.6619 0.9971 221125_WJC_METTL3_EV_vs_WT_F07.04344.04344.2 0.0217 12-Jun K.QESTEYR.R "sp|P08670|VIME_HUMAN,tr|B0YJC5|B0YJC5_HUMAN,tr|B0YJC4|B0YJC4_HUMAN" 3 911.3985 2.1 93566 4344 2 911.398775 456.7065 Vimentin OS=Homo sapiens OX=9606 GN=VIM PE=1 SV=4 4.53 1392.8 - 2.26E+06 - - - 0.3292 - 1.145 0.279 - 161 1 2 0 0.0003 7 0 0 0 2.41E+07 1.15E+07 - - - 1.5306 0.9998 221125_WJC_METTL3_EV_vs_WT_F07.04347.04347.2 0.000225 22-Aug K.LATEGSSGATEK.M sp|Q9NW68|BSDC1_HUMAN 1 1149.5513 0.17 93569 4347 2 1149.551668 575.7829 BSD domain-containing protein 1 OS=Homo sapiens OX=9606 GN=BSDC1 PE=1 SV=1 4.53 1393.1 - 423810 - - - 0.2792 - 1.923 0.449 - 199.6 1 2 0 0.0003 12 0 0 0 3.86E+06 2.27E+07 - - - 4.0777 0.9998 221125_WJC_METTL3_EV_vs_WT_F07.04351.04351.2 0.00132 13/18 R.KLQANGPVAK.K "sp|Q14978|NOLC1_HUMAN,tr|S4R3C2|S4R3C2_HUMAN,tr|A0A0A0MRM9|A0A0A0MRM9_HUMAN" 3 1024.6029 1.9 93571 4351 2 1024.604554 513.3087 Nucleolar and coiled-body phosphoprotein 1 OS=Homo sapiens OX=9606 GN=NOLC1 PE=1 SV=2 10 1393.5 - 2.26E+06 - - - 1.586 - 2.476 0.473 - 533.2 1 2 0 0.0016 10 0 0 0 1.90E+08 9.98E+07 - - - 5.0648 0.9994 221125_WJC_METTL3_EV_vs_WT_F07.04358.04358.2 0.00216 14-Sep K.KETSNLYK.L "sp|O75323|NIPS2_HUMAN,sp|Q9BPW8|NIPS1_HUMAN,tr|H7C2U6|H7C2U6_HUMAN,tr|F8WBI5|F8WBI5_HUMAN,tr|F8WCR5|F8WCR5_HUMAN" 5 981.5131 61.2 93576 4358 2 981.511544 491.7638 Protein NipSnap homolog 2 OS=Homo sapiens OX=9606 GN=NIPSNAP2 PE=1 SV=1 8.5 1394.3 - 3.98E+06 - - - -1.5965 - 1.898 0.319 - 251.3 1 2 0 -0.0016 8 0 0 0 6.14E+07 1.00E+06 - - - 3.3293 0.9999 221125_WJC_METTL3_EV_vs_WT_F07.04366.04366.2 3.09E-05 16-Dec K.IVEHQNLSK[136.11].K sp|Q9H501|ESF1_HUMAN 1 1074.5913 1.16 93582 4366 2 1074.591187 538.3029 ESF1 homolog OS=Homo sapiens OX=9606 GN=ESF1 PE=1 SV=1 6.75 1395.2 - 2.01E+06 - - - -0.1126 - 2.445 0.458 - 487 1 2 0 -0.0001 9 0 0 0 2.71E+07 2.34E+07 - - - 5.0103 0.9995 221125_WJC_METTL3_EV_vs_WT_F07.04372.04372.2 0.00877 16-Oct K.IVEHQNLSK.K sp|Q9H501|ESF1_HUMAN 1 1066.5771 1.13 93586 4372 2 1066.575833 534.2958 ESF1 homolog OS=Homo sapiens OX=9606 GN=ESF1 PE=1 SV=1 6.75 1395.8 - 1.83E+06 - - - -1.1954 - 1.585 0.4 - 222.2 1 2 0 -0.0013 9 0 0 0 2.67E+07 2.36E+07 - - - 3.3275 0.999 221125_WJC_METTL3_EV_vs_WT_F07.04373.04373.2 0.00103 14-Jul R.SYDTDQGR[166.11].V "sp|Q9HA64|KT3K_HUMAN,tr|I3L3W5|I3L3W5_HUMAN,tr|I3L407|I3L407_HUMAN,tr|I3L139|I3L139_HUMAN" 4 950.3969 0.27 93587 4373 2 950.395102 476.2057 Ketosamine-3-kinase OS=Homo sapiens OX=9606 GN=FN3KRP PE=1 SV=2 4.21 1395.9 - 2.10E+06 - - - -1.9013 - 1.192 0.466 - 153.7 1 2 0 -0.0018 8 0 0 0 1.17E+07 4.35E+07 - - - 3.012 0.9999 221125_WJC_METTL3_EV_vs_WT_F07.04379.04379.2 0.000168 18-Nov R.K[136.11]LQANGPVAK[136.11].K "sp|Q14978|NOLC1_HUMAN,tr|S4R3C2|S4R3C2_HUMAN,tr|A0A0A0MRM9|A0A0A0MRM9_HUMAN" 3 1040.6313 1.9 93591 4379 2 1040.630383 521.3229 Nucleolar and coiled-body phosphoprotein 1 OS=Homo sapiens OX=9606 GN=NOLC1 PE=1 SV=2 10 1396.6 - 8.18E+06 - - - -0.9091 - 2.401 0.447 - 416 1 2 0 -0.0009 10 0 0 0 1.90E+08 9.98E+07 - - - 4.7871 0.9998 221125_WJC_METTL3_EV_vs_WT_F07.04386.04386.2 0.000997 16-Aug R.ATNYNAGDR.S "sp|P61626|LYSC_HUMAN,tr|A0A0B4J259|A0A0B4J259_HUMAN,tr|F8VV32|F8VV32_HUMAN" 3 980.4312 747.13 93596 4386 2 980.429531 491.2229 Lysozyme C OS=Homo sapiens OX=9606 GN=LYZ PE=1 SV=1 5.88 1397.3 - 5.07E+06 - - - -1.6738 - 1.785 0.545 - 407.1 1 2 0 -0.0016 9 0 0 0 6.39E+08 8.55E+05 - - - 4.7421 0.9963 221125_WJC_METTL3_EV_vs_WT_F07.04388.04388.3 0.0309 Dec-40 K.YIGTGHADTTK.W sp|Q9BWJ5|SF3B5_HUMAN 1 1162.5619 1.06 93598 4388 3 1162.556189 388.5279 Splicing factor 3B subunit 5 OS=Homo sapiens OX=9606 GN=SF3B5 PE=1 SV=1 6.74 1397.5 - 1.02E+06 - - - -4.8711 - 2.384 0.301 - 151.3 1 2 0 -0.0057 11 0 0 0 4.90E+07 4.60E+07 - - - 4.3623 0.8751 221125_WJC_METTL3_EV_vs_WT_F07.04392.04392.2 7.52 14-May K.K[136.11]FGNPGER[166.11].L "sp|Q92841|DDX17_HUMAN,tr|A0A5H1ZRQ2|A0A5H1ZRQ2_HUMAN,tr|A0A1X7SBZ2|A0A1X7SBZ2_HUMAN" 3 921.4787 2.02 93601 4392 2 921.477981 461.7466 Probable ATP-dependent RNA helicase DDX17 OS=Homo sapiens OX=9606 GN=DDX17 PE=1 SV=2 8.75 1397.9 - 2.08E+06 - - - -0.8183 - 0.959 0.014 - 98 1 2 0 -0.0008 8 0 0 0 1.51E+08 7.48E+07 - - - -0.9821 0.9956 221125_WJC_METTL3_EV_vs_WT_F07.04394.04394.2 1.71 14-Jul K.KLAEPAER.Y "sp|Q92615|LAR4B_HUMAN,tr|A0A087X183|A0A087X183_HUMAN,tr|H0Y4V9|H0Y4V9_HUMAN" 3 912.5029 0.88 93602 4394 2 912.502143 457.2587 La-related protein 4B OS=Homo sapiens OX=9606 GN=LARP4B PE=1 SV=3 6.14 1398.2 - 5.44E+06 - - - -0.8088 - 1.443 0.153 - 197.5 1 2 0 -0.0007 8 0 0 0 6.75E+07 7.66E+07 - - - 1.2769 0.9994 221125_WJC_METTL3_EV_vs_WT_F07.04395.04395.2 0.00228 18-Aug R.LKPTNPAAQK.A "sp|P52948|NUP98_HUMAN,tr|A0A3B3ITD8|A0A3B3ITD8_HUMAN,tr|H0YEN4|H0YEN4_HUMAN,tr|H0YCR0|H0YCR0_HUMAN" 4 1066.6135 1.58 93603 4395 2 1066.613246 534.314 Nuclear pore complex protein Nup98-Nup96 OS=Homo sapiens OX=9606 GN=NUP98 PE=1 SV=4 10 1398.2 - 1.42E+06 - - - -0.2325 - 1.582 0.343 - 122 1 2 0 -0.0002 10 0 0 0 3.04E+08 1.93E+08 - - - 2.8547 0.9998 221125_WJC_METTL3_EV_vs_WT_F07.04396.04396.2 1.45E-05 20-Nov K.YDTGASTTGSK[136.11].K "sp|Q9Y618|NCOR2_HUMAN,tr|C9J7T7|C9J7T7_HUMAN,tr|C9JE98|C9JE98_HUMAN,tr|C9J0Q5|C9J0Q5_HUMAN,tr|A0A384DVL6|A0A384DVL6_HUMAN" 5 1094.4971 1.88 93604 4396 2 1094.495121 548.2558 Nuclear receptor corepressor 2 OS=Homo sapiens OX=9606 GN=NCOR2 PE=1 SV=3 5.83 1398.4 - 1.20E+06 - - - -1.8383 - 2.289 0.524 - 285 1 2 0 -0.002 11 0 0 0 4.39E+07 2.33E+07 - - - 5.1509 0.9994 221125_WJC_METTL3_EV_vs_WT_F07.04400.04400.2 0.000159 20-Sep K.TIESANQQTDK[136.11].L "sp|O76094|SRP72_HUMAN,tr|R4GNC1|R4GNC1_HUMAN,tr|D6RDY6|D6RDY6_HUMAN" 3 1241.5979 0.52 93608 4400 2 1241.596036 621.8062 Signal recognition particle subunit SRP72 OS=Homo sapiens OX=9606 GN=SRP72 PE=1 SV=3 4.37 1398.8 - 560855 - - - -1.5093 - 1.674 0.378 - 121.6 1 2 0 -0.0019 11 0 0 0 3.99E+06 7.71E+06 - - - 3.2261 0.9996 221125_WJC_METTL3_EV_vs_WT_F07.04401.04401.2 8.28E-05 20-Oct K.YIGTGHADTTK[136.11].W sp|Q9BWJ5|SF3B5_HUMAN 1 1170.5761 0.63 93609 4401 2 1170.57694 586.2953 Splicing factor 3B subunit 5 OS=Homo sapiens OX=9606 GN=SF3B5 PE=1 SV=1 6.74 1398.9 - 280181 - - - 0.7586 - 1.734 0.41 - 221.7 1 2 0 0.0009 11 0 0 0 7.37E+06 1.17E+07 - - - 3.558 0.9934 221125_WJC_METTL3_EV_vs_WT_F07.04402.04402.2 1.66E-05 20-Sep K.YIGTGHADTTK.W sp|Q9BWJ5|SF3B5_HUMAN 1 1162.5619 0.63 93610 4402 2 1162.554327 582.2882 Splicing factor 3B subunit 5 OS=Homo sapiens OX=9606 GN=SF3B5 PE=1 SV=1 6.74 1399.1 - 258330 - - - -6.4728 - 1.825 0.562 - 187.4 1 2 0 -0.0075 11 0 0 0 7.37E+06 1.17E+07 - - - 4.817 0.9999 221125_WJC_METTL3_EV_vs_WT_F07.04406.04406.3 0.00931 13/40 K.YIGTGHADTTK[136.11].W sp|Q9BWJ5|SF3B5_HUMAN 1 1170.5761 1.05 93612 4406 3 1170.573625 391.1993 Splicing factor 3B subunit 5 OS=Homo sapiens OX=9606 GN=SF3B5 PE=1 SV=1 6.74 1399.5 - 3.79E+06 - - - -2.0733 - 2.36 0.499 - 160.2 1 2 0 -0.0024 11 0 0 0 4.92E+07 4.70E+07 - - - 6.542 0.9985 221125_WJC_METTL3_EV_vs_WT_F07.04409.04409.2 0.0807 12-Jun R.HLNYGSR.L sp|Q9UBZ4|APEX2_HUMAN 1 845.4144 1.03 93615 4409 2 845.41342 423.7145 DNA-(apurinic or apyrimidinic site) endonuclease 2 OS=Homo sapiens OX=9606 GN=APEX2 PE=1 SV=1 8.75 1399.7 - 567621 - - - -1.1592 - 1.215 0.349 - 114.1 1 2 0 -0.001 7 0 0 0 3.40E+07 3.31E+07 - - - 2.2355 0.9875 221125_WJC_METTL3_EV_vs_WT_F07.04410.04410.2 0.0133 18-Jul K.VVLSSQDKDK.S "sp|Q15155|NOMO1_HUMAN,sp|Q5JPE7|NOMO2_HUMAN,sp|P69849|NOMO3_HUMAN,tr|A0A7I2V3P4|A0A7I2V3P4_HUMAN,tr|A0A7I2V6B0|A0A7I2V6B0_HUMAN,tr|A0A7I2V4D7|A0A7I2V4D7_HUMAN,tr|A0A7I2V4T6|A0A7I2V4T6_HUMAN,tr|A0A0G2JP90|A0A0G2JP90_HUMAN,tr|A0A087X117|A0A087X117_HUMAN,tr|A0A0G2JN29|A0A0G2JN29_HUMAN,tr|A0A7I2V2Z5|A0A7I2V2Z5_HUMAN,tr|A0A087WW46|A0A087WW46_HUMAN,tr|J3KN36|J3KN36_HUMAN" 13 1117.5979 4.61 93616 4410 2 1117.598341 559.8062 Nodal modulator 1 OS=Homo sapiens OX=9606 GN=NOMO1 PE=1 SV=5 5.93 1399.8 - 529802 - - - 0.3919 - 1.386 0.32 - 140.3 1 2 1 0.0004 10 0 0 0 8.97E+07 1.95E+07 - - - 2.3155 0.9999 221125_WJC_METTL3_EV_vs_WT_F07.04412.04412.2 9.85E-06 20-Oct K.TIESANQQTDK.L "sp|O76094|SRP72_HUMAN,tr|R4GNC1|R4GNC1_HUMAN,tr|D6RDY6|D6RDY6_HUMAN" 3 1233.5837 0.52 93618 4412 2 1233.584715 617.7991 Signal recognition particle subunit SRP72 OS=Homo sapiens OX=9606 GN=SRP72 PE=1 SV=3 4.37 1400.1 - 396707 - - - 0.8147 - 1.922 0.616 - 179.5 1 2 0 0.001 11 0 0 0 3.99E+06 7.71E+06 - - - 5.358 0.9993 221125_WJC_METTL3_EV_vs_WT_F07.04417.04417.2 0.091 14-Aug R.ESNVLHEK.S "sp|Q9NX62|IMPA3_HUMAN,tr|H0YBS3|H0YBS3_HUMAN" 2 954.4771 5.35 93621 4417 2 954.477218 478.2458 "Golgi-resident adenosine 3',5'-bisphosphate 3'-phosphatase OS=Homo sapiens OX=9606 GN=BPNT2 PE=1 SV=1" 5.4 1400.7 - 4.04E+06 - - - 0.1655 - 1.59 0.311 - 388.6 1 2 0 0.0002 8 0 0 0 8.58E+07 1.60E+07 - - - 2.7366 0.9998 221125_WJC_METTL3_EV_vs_WT_F07.04418.04418.2 2.80E-05 16-Dec R.R[166.11]LPEESGGR[166.11].H "sp|Q96T37|RBM15_HUMAN,tr|A0A494C001|A0A494C001_HUMAN,tr|A0A499FJY3|A0A499FJY3_HUMAN,tr|A0A087WWP4|A0A087WWP4_HUMAN" 4 1019.5263 1.1 93622 4418 2 1019.52619 510.7704 RNA-binding protein 15 OS=Homo sapiens OX=9606 GN=RBM15 PE=1 SV=2 6.14 1400.7 - 3.20E+06 - - - -0.105 - 2.526 0.321 - 286.6 1 2 0 -0.0001 9 0 0 0 3.51E+07 3.17E+07 - - - 4.0927 0.9996 221125_WJC_METTL3_EV_vs_WT_F07.04419.04419.3 0.00125 Sep-40 K.VAGHPLAQNER.C sp|O60493|SNX3_HUMAN 1 1190.6156 0.11 93623 4419 3 1190.61447 397.8791 Sorting nexin-3 OS=Homo sapiens OX=9606 GN=SNX3 PE=1 SV=3 6.72 1400.8 - 2.24E+06 - - - -0.965 - 1.706 0.349 - 97.8 1 2 0 -0.0011 11 0 0 0 3.44E+07 3.27E+08 - - - 3.9481 0.9969 221125_WJC_METTL3_EV_vs_WT_F07.04421.04421.2 0.105 14-Jul R.YANNSNYK.N "sp|Q96A72|MGN2_HUMAN,sp|P61326|MGN_HUMAN,tr|F5H6N1|F5H6N1_HUMAN" 3 972.4301 20.24 93625 4421 2 972.429356 487.2223 Protein mago nashi homolog 2 OS=Homo sapiens OX=9606 GN=MAGOHB PE=1 SV=1 8.5 1400.9 - 1.61E+06 - - - -0.7754 - 1.092 0.301 - 87.8 1 2 0 -0.0008 8 0 0 0 1.71E+07 8.43E+05 - - - 1.5294 0.9739 221125_WJC_METTL3_EV_vs_WT_F07.04422.04422.2 0.0762 12-Jun R.THYDPPR.K "sp|P55795|HNRH2_HUMAN,sp|P31943|HNRH1_HUMAN,tr|H0YBD7|H0YBD7_HUMAN,tr|H0YB39|H0YB39_HUMAN,tr|E5RGV0|E5RGV0_HUMAN,tr|E9PCY7|E9PCY7_HUMAN,tr|D6RBM0|D6RBM0_HUMAN,tr|G8JLB6|G8JLB6_HUMAN,tr|E7EN40|E7EN40_HUMAN" 9 884.4141 1.43 93626 4422 2 884.411312 443.2143 Heterogeneous nuclear ribonucleoprotein H2 OS=Homo sapiens OX=9606 GN=HNRNPH2 PE=1 SV=1 6.41 1401 - 1.77E+06 - - - -3.1139 - 1.218 0.186 - 162.3 1 2 0 -0.0028 7 0 0 0 4.93E+08 3.44E+08 - - - 1.0388 0.9854 221125_WJC_METTL3_EV_vs_WT_F07.04423.04423.2 0.786 12-Jun R.THYDPPR[166.11].K "sp|P55795|HNRH2_HUMAN,sp|P31943|HNRH1_HUMAN,tr|H0YBD7|H0YBD7_HUMAN,tr|H0YB39|H0YB39_HUMAN,tr|E5RGV0|E5RGV0_HUMAN,tr|E9PCY7|E9PCY7_HUMAN,tr|D6RBM0|D6RBM0_HUMAN,tr|G8JLB6|G8JLB6_HUMAN,tr|E7EN40|E7EN40_HUMAN" 9 894.4223 1.4 93627 4423 2 894.419597 448.2184 Heterogeneous nuclear ribonucleoprotein H2 OS=Homo sapiens OX=9606 GN=HNRNPH2 PE=1 SV=1 6.41 1401.1 - 1.29E+06 - - - -3.0623 - 1.278 0.22 - 162.9 1 2 0 -0.0027 7 0 0 0 4.79E+08 3.43E+08 - - - 1.4423 0.9314 221125_WJC_METTL3_EV_vs_WT_F07.04426.04426.2 0.858 20-May K.VAGHPLAQNER.C sp|O60493|SNX3_HUMAN 1 1190.6156 0.23 93629 4426 2 1190.620099 596.3151 Sorting nexin-3 OS=Homo sapiens OX=9606 GN=SNX3 PE=1 SV=3 6.72 1401.4 - 423347 - - - 3.7628 - 1.079 0.213 - 59.6 2 2 0 0.0045 11 0 0 0 5.41E+06 2.38E+07 - - - 0.684 0.9547 221125_WJC_METTL3_EV_vs_WT_F07.04430.04430.2 2.4 18-Jun R.LK[136.11]PTNPAAQK[136.11].A "sp|P52948|NUP98_HUMAN,tr|A0A3B3ITD8|A0A3B3ITD8_HUMAN,tr|H0YEN4|H0YEN4_HUMAN,tr|H0YCR0|H0YCR0_HUMAN" 4 1082.6419 1.58 93631 4430 2 1082.640818 542.3282 Nuclear pore complex protein Nup98-Nup96 OS=Homo sapiens OX=9606 GN=NUP98 PE=1 SV=4 10 1401.9 - 3.27E+06 - - - -0.9939 - 1.065 0.131 - 58.5 10 2 0 -0.0011 10 0 0 0 3.05E+08 1.93E+08 - - - -0.2627 0.9998 221125_WJC_METTL3_EV_vs_WT_F07.04432.04432.2 0.00111 14/22 R.AEAGEQPGTAER[166.11].A sp|P56182|RRP1_HUMAN 1 1224.561 0.71 93633 4432 2 1224.559218 613.2878 Ribosomal RNA processing protein 1 homolog A OS=Homo sapiens OX=9606 GN=RRP1 PE=1 SV=1 4.25 1402 - 765858 - - - -1.4666 - 2.604 0.409 - 646.2 1 2 0 -0.0018 12 0 0 0 1.99E+07 2.79E+07 - - - 4.5795 0.9713 221125_WJC_METTL3_EV_vs_WT_F07.04433.04433.2 0.00883 14-Jul K.TDEGHPFK.A "sp|Q16799|RTN1_HUMAN,tr|A8MT72|A8MT72_HUMAN,tr|Q2NKQ5|Q2NKQ5_HUMAN" 3 929.4243 1.15 93634 4433 2 929.423008 465.7194 Reticulon-1 OS=Homo sapiens OX=9606 GN=RTN1 PE=1 SV=1 5.29 1402.1 - 740314 - - - -1.3858 - 1.397 0.015 - 237.1 1 2 0 -0.0013 8 0 0 0 2.37E+07 2.07E+07 - - - 0.1597 0.9998 221125_WJC_METTL3_EV_vs_WT_F07.04442.04442.2 1.10E-05 20-Dec K.TVEQTATTTNK.K sp|P08579|RU2B_HUMAN 1 1192.5935 1.91 93640 4442 2 1192.590891 597.304 U2 small nuclear ribonucleoprotein B'' OS=Homo sapiens OX=9606 GN=SNRPB2 PE=1 SV=1 5.66 1403.1 - 680048 - - - -2.2262 - 2.084 0.574 - 334.5 1 2 0 -0.0027 11 0 0 0 1.29E+08 6.75E+07 - - - 5.2662 0.9993 221125_WJC_METTL3_EV_vs_WT_F07.04451.04451.2 0.0297 18-Oct K.YVHADAPTNK[136.11].T "sp|Q92922|SMRC1_HUMAN,tr|F8WE13|F8WE13_HUMAN" 2 1122.5549 4.93 93647 4451 2 1122.556348 562.2847 SWI\SNF complex subunit SMARCC1 OS=Homo sapiens OX=9606 GN=SMARCC1 PE=1 SV=3 6.74 1404.3 - 366042 - - - 1.2694 - 1.42 0.415 - 203.9 1 2 0 0.0014 10 0 0 0 1.08E+07 2.20E+06 - - - 3.0845 0.9998 221125_WJC_METTL3_EV_vs_WT_F07.04455.04455.3 0.000105 13/36 K.FEETTADGRK.T "sp|Q01469|FABP5_HUMAN,tr|I6L8B7|I6L8B7_HUMAN" 2 1152.5411 18.75 93649 4455 3 1152.538142 385.1876 Fatty acid-binding protein 5 OS=Homo sapiens OX=9606 GN=FABP5 PE=1 SV=3 4.68 1404.8 - 1.36E+06 - - - -2.5813 - 1.985 0.469 - 189.1 1 2 0 -0.003 10 0 0 0 3.84E+08 2.05E+07 - - - 5.7704 0.9997 221125_WJC_METTL3_EV_vs_WT_F07.04456.04456.2 0.00265 14-Sep K.K[136.11]VGDDIAK[136.11].A sp|P30050|RL12_HUMAN 1 860.4938 2.58 93650 4456 2 860.492812 431.2542 60S ribosomal protein L12 OS=Homo sapiens OX=9606 GN=RPL12 PE=1 SV=1 5.96 1404.8 - 1.31E+07 - - - -1.1854 - 2.028 0.362 - 272.9 1 2 0 -0.001 8 0 0 0 8.10E+08 3.13E+08 - - - 3.8468 0.9999 221125_WJC_METTL3_EV_vs_WT_F07.04459.04459.2 6.04E-07 22-Nov K.LTNSSSTGTVGK[136.11].N sp|Q6ZU65|UBN2_HUMAN 1 1158.5972 1.18 93653 4459 2 1158.596082 580.3059 Ubinuclein-2 OS=Homo sapiens OX=9606 GN=UBN2 PE=1 SV=2 8.75 1405.1 - 1.21E+06 - - - -0.9486 - 2.551 0.567 - 397.1 1 2 0 -0.0011 12 0 0 0 1.10E+08 9.38E+07 - - - 5.6926 0.9966 221125_WJC_METTL3_EV_vs_WT_F07.04460.04460.2 0.0601 16-Jul R.SHLDSPEAR[166.11].E "sp|Q9BTD8|RBM42_HUMAN,tr|K7ER08|K7ER08_HUMAN,tr|K7EP90|K7EP90_HUMAN" 3 1020.4864 1.88 93654 4460 2 1020.484436 511.2505 RNA-binding protein 42 OS=Homo sapiens OX=9606 GN=RBM42 PE=1 SV=1 5.3 1405.1 - 970436 - - - -1.9167 - 1.502 0.233 - 229 1 2 0 -0.002 9 0 0 0 8.95E+08 4.77E+08 - - - 1.9382 1 221125_WJC_METTL3_EV_vs_WT_F07.04461.04461.2 6.07E-08 13/22 K.LTNSSSTGTVGK.N sp|Q6ZU65|UBN2_HUMAN 1 1150.583 1.18 93655 4461 2 1150.581447 576.2988 Ubinuclein-2 OS=Homo sapiens OX=9606 GN=UBN2 PE=1 SV=2 8.75 1405.3 - 776708 - - - -1.3332 - 2.677 0.587 - 516 1 2 0 -0.0015 12 0 0 0 1.10E+08 9.38E+07 - - - 5.967 0.8485 221125_WJC_METTL3_EV_vs_WT_F07.04468.04468.2 2.59 16-Sep L.KPTNPAAQK.A "sp|P52948|NUP98_HUMAN,tr|A0A3B3ITD8|A0A3B3ITD8_HUMAN,tr|H0YEN4|H0YEN4_HUMAN,tr|H0YCR0|H0YCR0_HUMAN" 4 953.5294 2.13 93658 4468 2 953.530819 477.772 Nuclear pore complex protein Nup98-Nup96 OS=Homo sapiens OX=9606 GN=NUP98 PE=1 SV=4 10 1406.2 - 448194 - - - 1.4567 - 1.77 0.162 - 237.1 1 1 0 0.0014 9 0 0 0 1.33E+07 6.27E+06 - - - 1.889 0.9992 221125_WJC_METTL3_EV_vs_WT_F07.04471.04471.2 0.0435 14-Sep R.KVTLSTDK.N "sp|P41252|SYIC_HUMAN,tr|A0A804HL54|A0A804HL54_HUMAN,tr|A0A804HIV9|A0A804HIV9_HUMAN,tr|A0A804HJN6|A0A804HJN6_HUMAN,tr|A0A804HHW9|A0A804HHW9_HUMAN,tr|A0A0A0MSX9|A0A0A0MSX9_HUMAN,tr|J3KR24|J3KR24_HUMAN,tr|A0A804HJ36|A0A804HJ36_HUMAN" 8 890.5073 1.01 93660 4471 2 890.506189 446.2609 "Isoleucine--tRNA ligase, cytoplasmic OS=Homo sapiens OX=9606 GN=IARS1 PE=1 SV=2" 8.59 1406.5 - 3.90E+06 - - - -1.2442 - 1.742 0.29 - 351.2 1 2 0 -0.0011 8 0 0 0 9.20E+07 9.07E+07 - - - 2.8565 0.9995 221125_WJC_METTL3_EV_vs_WT_F07.04473.04473.2 0.000118 16-Sep R.DSHGVAQVR[166.11].F "sp|P62277|RS13_HUMAN,tr|J3KMX5|J3KMX5_HUMAN,tr|E9PS50|E9PS50_HUMAN" 3 977.4918 1 93661 4473 2 977.490744 489.7532 40S ribosomal protein S13 OS=Homo sapiens OX=9606 GN=RPS13 PE=1 SV=2 6.74 1406.7 - 4.34E+06 - - - -1.0926 - 1.505 0.408 - 276.5 1 2 0 -0.0011 9 0 0 0 3.72E+08 3.74E+08 - - - 3.2368 0.9999 221125_WJC_METTL3_EV_vs_WT_F07.04475.04475.2 1.61E-05 20-Nov K.TSPVVSGSSSK.S "sp|Q5SW79|CE170_HUMAN,tr|H0Y2V6|H0Y2V6_HUMAN" 2 1034.5244 1.07 93663 4475 2 1034.524444 518.2695 Centrosomal protein of 170 kDa OS=Homo sapiens OX=9606 GN=CEP170 PE=1 SV=1 8.41 1406.8 - 3.38E+06 - - - 0.0387 - 1.763 0.551 - 446.4 1 2 0 0 11 0 0 0 7.20E+07 6.75E+07 - - - 4.6446 0.9994 221125_WJC_METTL3_EV_vs_WT_F07.04483.04483.2 0.00271 14-Oct K.KVGDDIAK.A sp|P30050|RL12_HUMAN 1 844.4654 1.4 93668 4483 2 844.464804 423.24 60S ribosomal protein L12 OS=Homo sapiens OX=9606 GN=RPL12 PE=1 SV=1 5.96 1407.8 - 2.90E+07 - - - -0.7437 - 2.048 0.224 - 335.5 1 2 0 -0.0006 8 0 0 0 4.21E+08 3.00E+08 - - - 2.8573 0.9985 221125_WJC_METTL3_EV_vs_WT_F07.04485.04485.2 0.0026 16-Dec K.LKQDLNDEK.K "sp|Q15643|TRIPB_HUMAN,tr|H0YJ97|H0YJ97_HUMAN" 2 1101.5666 1.61 93670 4485 2 1101.566046 551.7906 Thyroid receptor-interacting protein 11 OS=Homo sapiens OX=9606 GN=TRIP11 PE=1 SV=3 4.56 1407.9 - 5.07E+06 - - - -0.5056 - 2.348 0.439 - 337.9 1 2 1 -0.0006 9 0 0 0 1.44E+08 8.98E+07 - - - 4.7527 0.9953 221125_WJC_METTL3_EV_vs_WT_F07.04491.04491.2 0.923 14-Jun R.SEIDNVKK.Q sp|P04264|K2C1_HUMAN 1 931.4975 306.13 93674 4491 2 931.497339 466.756 "Keratin, type II cytoskeletal 1 OS=Homo sapiens OX=9606 GN=KRT1 PE=1 SV=6" 5.79 1408.6 - 5.78E+06 - - - -0.131 - 1.184 0.215 - 161.3 1 2 0 -0.0001 8 0 0 0 3.27E+09 1.07E+07 - - - 1.1383 0.989 221125_WJC_METTL3_EV_vs_WT_F07.04493.04493.2 0.0343 12-Jun K.KYIDNPK.L "sp|Q92499|DDX1_HUMAN,tr|A0A7I2V2M5|A0A7I2V2M5_HUMAN,tr|A0A087X2G1|A0A087X2G1_HUMAN,tr|A0A7I2V430|A0A7I2V430_HUMAN,tr|A0A7I2V421|A0A7I2V421_HUMAN,tr|A0A7I2V4F0|A0A7I2V4F0_HUMAN,tr|A0A7I2V5X8|A0A7I2V5X8_HUMAN,tr|A0A7I2V4J3|A0A7I2V4J3_HUMAN,tr|A0A087WZ71|A0A087WZ71_HUMAN,tr|A0A7I2YQ77|A0A7I2YQ77_HUMAN" 10 876.4705 1.15 93676 4493 2 876.470442 439.2425 ATP-dependent RNA helicase DDX1 OS=Homo sapiens OX=9606 GN=DDX1 PE=1 SV=2 8.5 1408.7 - 2.47E+06 - - - -0.0867 - 1.32 0.085 - 158.6 1 2 0 -0.0001 7 0 0 0 5.64E+07 4.88E+07 - - - 0.5485 0.9981 221125_WJC_METTL3_EV_vs_WT_F07.04501.04501.2 0.00483 16-Jul K.ETQSPEQVK[136.11].S "sp|Q9NYF8|BCLF1_HUMAN,tr|E9PKI6|E9PKI6_HUMAN,tr|A0A1W2PQ43|A0A1W2PQ43_HUMAN,tr|E9PK91|E9PK91_HUMAN,tr|E9PK09|E9PK09_HUMAN,tr|E9PQN2|E9PQN2_HUMAN" 6 1052.523 2.57 93682 4501 2 1052.521821 527.2688 Bcl-2-associated transcription factor 1 OS=Homo sapiens OX=9606 GN=BCLAF1 PE=1 SV=2 4.53 1409.6 - 3.25E+06 - - - -1.0765 - 1.429 0.261 - 238.5 1 2 0 -0.0011 9 0 0 0 5.27E+09 2.05E+09 - - - 2.0011 0.7789 221125_WJC_METTL3_EV_vs_WT_F07.04503.04503.2 0.2 14-Jul D.SHGVAQVR.F "sp|P62277|RS13_HUMAN,tr|J3KMX5|J3KMX5_HUMAN,tr|E9PS50|E9PS50_HUMAN" 3 852.4566 1.69 93684 4503 2 852.455736 427.2356 40S ribosomal protein S13 OS=Homo sapiens OX=9606 GN=RPS13 PE=1 SV=2 9.49 1409.7 - 1.57E+06 - - - -1.0124 - 1.263 0.208 - 241.5 1 1 0 -0.0009 8 0 0 0 3.01E+07 1.78E+07 - - - 1.2812 0.9999 221125_WJC_METTL3_EV_vs_WT_F07.04505.04505.2 4.99E-05 24-Dec K.EAEGGAATAGPSR[166.11].E sp|Q9P253|VPS18_HUMAN 1 1182.5504 0.39 93686 4505 2 1182.549261 592.2825 Vacuolar protein sorting-associated protein 18 homolog OS=Homo sapiens OX=9606 GN=VPS18 PE=1 SV=2 4.53 1409.9 - 476703 - - - -1.0046 - 2.283 0.51 - 561.5 1 2 0 -0.0012 13 0 0 0 7.27E+06 1.84E+07 - - - 4.9261 0.9915 221125_WJC_METTL3_EV_vs_WT_F07.04510.04510.2 9.88E-05 18-Sep R.R[166.11]AEQDSTTVA.A "sp|Q86U44|MTA70_HUMAN,tr|F5H6D8|F5H6D8_HUMAN,tr|H0YFV6|H0YFV6_HUMAN,tr|B4DTN4|B4DTN4_HUMAN" 4 1086.5181 0.09 93689 4510 2 1086.517819 544.2663 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 4.37 1410.6 - 1.30E+07 - - - -0.2457 - 1.803 0.526 - 371.6 1 1 0 -0.0003 10 0 0 0 6.91E+07 7.78E+08 - - - 4.5713 1 221125_WJC_METTL3_EV_vs_WT_F07.04511.04511.2 2.41E-06 14-Dec K.HYAMQEAK[136.11].Q "sp|Q14257|RCN2_HUMAN,tr|H0YL43|H0YL43_HUMAN" 2 984.4579 0.89 93690 4511 2 984.456433 493.2362 Reticulocalbin-2 OS=Homo sapiens OX=9606 GN=RCN2 PE=1 SV=1 6.75 1410.6 - 3.88E+06 - - - -1.4404 - 2.126 0.602 - 509.2 1 2 0 -0.0014 8 0 0 0 7.95E+07 8.91E+07 - - - 5.7617 0.9511 221125_WJC_METTL3_EV_vs_WT_F07.04514.04514.2 0.00823 20-Jun R.LENNDNK[136.11]PVTN.S "sp|Q9BYJ9|YTHD1_HUMAN,sp|Q7Z739|YTHD3_HUMAN,tr|A0A087X0Q1|A0A087X0Q1_HUMAN,tr|A0A024R7W5|A0A024R7W5_HUMAN,tr|A0A087WY31|A0A087WY31_HUMAN" 5 1264.6139 1.87 93693 4514 2 1264.614079 633.3142 YTH domain-containing family protein 1 OS=Homo sapiens OX=9606 GN=YTHDF1 PE=1 SV=1 4.37 1410.9 - 368556 - - - 0.1463 - 1.482 0.327 - 131.5 1 1 0 0.0002 11 0 0 0 1.49E+07 7.95E+06 - - - 2.5204 0.9997 221125_WJC_METTL3_EV_vs_WT_F07.04525.04525.2 0.000212 18-Oct K.FEETTADGRK.T "sp|Q01469|FABP5_HUMAN,tr|I6L8B7|I6L8B7_HUMAN" 2 1152.5411 835.69 93700 4525 2 1152.540061 577.2778 Fatty acid-binding protein 5 OS=Homo sapiens OX=9606 GN=FABP5 PE=1 SV=3 4.68 1412.1 - 1.37E+06 - - - -0.9162 - 1.76 0.417 - 268.7 1 2 0 -0.0011 10 0 0 0 5.72E+07 6.85E+04 - - - 3.6986 0.9997 221125_WJC_METTL3_EV_vs_WT_F07.04531.04531.2 0.00206 20-Aug R.FSASSGGGGSR.G "sp|P78344|IF4G2_HUMAN,tr|H0YD99|H0YD99_HUMAN,tr|H0YCF8|H0YCF8_HUMAN,tr|H0YEC5|H0YEC5_HUMAN,tr|H0YDC0|H0YDC0_HUMAN,tr|H0YEN8|H0YEN8_HUMAN,tr|H0Y3P2|H0Y3P2_HUMAN,tr|H0YCH5|H0YCH5_HUMAN,tr|H0YD77|H0YD77_HUMAN,tr|D3DQV9|D3DQV9_HUMAN" 10 968.4312 2.03 93704 4531 2 968.430095 485.2229 Eukaryotic translation initiation factor 4 gamma 2 OS=Homo sapiens OX=9606 GN=EIF4G2 PE=1 SV=1 9.75 1412.7 - 2.85E+07 - - - -1.1121 - 1.586 0.489 - 153.1 1 2 0 -0.0011 11 0 0 0 8.95E+08 4.40E+08 - - - 3.9001 0.9997 221125_WJC_METTL3_EV_vs_WT_F07.04532.04532.2 0.00771 20-Aug R.FSASSGGGGSR[166.11].G "sp|P78344|IF4G2_HUMAN,tr|H0YD99|H0YD99_HUMAN,tr|H0YCF8|H0YCF8_HUMAN,tr|H0YEC5|H0YEC5_HUMAN,tr|H0YDC0|H0YDC0_HUMAN,tr|H0YEN8|H0YEN8_HUMAN,tr|H0Y3P2|H0Y3P2_HUMAN,tr|H0YCH5|H0YCH5_HUMAN,tr|H0YD77|H0YD77_HUMAN,tr|D3DQV9|D3DQV9_HUMAN" 10 978.4394 2.03 93705 4532 2 978.438871 490.227 Eukaryotic translation initiation factor 4 gamma 2 OS=Homo sapiens OX=9606 GN=EIF4G2 PE=1 SV=1 9.75 1412.8 - 1.62E+07 - - - -0.5836 - 1.691 0.455 - 186.9 1 2 0 -0.0006 11 0 0 0 8.95E+08 4.40E+08 - - - 3.8226 0.9914 221125_WJC_METTL3_EV_vs_WT_F07.04543.04543.2 0.00758 20-Jul R.EPAEQPGDGER[166.11].T "sp|Q14151|SAFB2_HUMAN,sp|Q15424|SAFB1_HUMAN" 2 1193.5188 1.61 93713 4543 2 1193.514819 597.7667 Scaffold attachment factor B2 OS=Homo sapiens OX=9606 GN=SAFB2 PE=1 SV=1 4 1413.8 - 350295 - - - -3.3481 - 1.339 0.297 - 147.6 1 2 0 -0.004 11 0 0 0 6.71E+07 4.17E+07 - - - 2.0231 0.9996 221125_WJC_METTL3_EV_vs_WT_F07.04548.04548.2 0.00042 14-Sep K.K[136.11]YEAAYGK[136.11].Q "sp|P40939|ECHA_HUMAN,tr|H0YFD6|H0YFD6_HUMAN,tr|A0A2R8Y4F5|A0A2R8Y4F5_HUMAN" 3 944.4938 0.58 93715 4548 2 944.491835 473.2542 "Trifunctional enzyme subunit alpha, mitochondrial OS=Homo sapiens OX=9606 GN=HADHA PE=1 SV=2" 8.43 1414.4 - 2.27E+06 - - - -2.1144 - 1.922 0.433 - 275.3 1 2 0 -0.002 8 0 0 0 3.31E+07 5.68E+07 - - - 4.209 0.9622 221125_WJC_METTL3_EV_vs_WT_F07.04549.04549.2 0.929 18-Jul R.RAQAEQAALR.Q sp|Q15149|PLEC_HUMAN 1 1112.6051 4.15 93716 4549 2 1112.603586 557.3098 Plectin OS=Homo sapiens OX=9606 GN=PLEC PE=1 SV=3 9.6 1414.6 - 626635 - - - -1.3194 - 1.24 0.079 - 69.1 4 2 0 -0.0015 10 0 0 0 2.21E+07 5.32E+06 - - - -0.0445 0.8945 221125_WJC_METTL3_EV_vs_WT_F07.04550.04550.2 0.00626 18-Aug R.RAEQDSTTVA.A "sp|Q86U44|MTA70_HUMAN,tr|F5H6D8|F5H6D8_HUMAN,tr|H0YFV6|H0YFV6_HUMAN,tr|B4DTN4|B4DTN4_HUMAN" 4 1076.5098 0.09 93717 4550 2 1076.509357 539.2622 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 4.37 1414.6 - 1.27E+06 - - - -0.4264 - 1.353 0.262 - 184.4 1 1 0 -0.0005 10 0 0 0 6.95E+07 7.80E+08 - - - 1.8199 0.9998 221125_WJC_METTL3_EV_vs_WT_F07.04556.04556.3 9.26E-05 14/44 R.AEAEAAAVHGAR[166.11].F "sp|Q5T8P6|RBM26_HUMAN,tr|E2PSN0|E2PSN0_HUMAN,tr|A0A087X0H9|A0A087X0H9_HUMAN" 3 1161.5766 1.24 93721 4556 3 1161.572453 388.1995 RNA-binding protein 26 OS=Homo sapiens OX=9606 GN=RBM26 PE=1 SV=3 5.4 1415.3 - 3.70E+06 - - - -3.5736 - 2.246 0.489 - 323.6 1 2 0 -0.0042 12 0 0 0 7.97E+07 6.44E+07 - - - 6.2336 0.999 221125_WJC_METTL3_EV_vs_WT_F07.04559.04559.2 0.00157 20-Aug R.EPAEQPGDGER.T "sp|Q14151|SAFB2_HUMAN,sp|Q15424|SAFB1_HUMAN" 2 1183.5105 1.61 93724 4559 2 1183.507691 592.7625 Scaffold attachment factor B2 OS=Homo sapiens OX=9606 GN=SAFB2 PE=1 SV=1 4 1415.6 - 1.15E+06 - - - -2.4115 - 1.636 0.41 - 169.7 1 2 0 -0.0029 11 0 0 0 7.14E+07 4.43E+07 - - - 3.4 0.9963 221125_WJC_METTL3_EV_vs_WT_F07.04561.04561.2 0.000178 18-Oct K.C[160.03]TQDLGNSTK[136.11].A sp|Q9Y490|TLN1_HUMAN 1 1130.5117 0.51 93726 4561 2 1130.507159 566.2631 Talin-1 OS=Homo sapiens OX=9606 GN=TLN1 PE=1 SV=3 5.83 1415.9 - 370367 - - - -4.0504 - 1.573 0.405 - 223.2 1 2 0 -0.0046 10 0 0 0 4.22E+06 8.35E+06 - - - 3.2953 0.9989 221125_WJC_METTL3_EV_vs_WT_F07.04564.04564.2 0.00858 16-Jul K.IIEDQNQSK.M "sp|Q15643|TRIPB_HUMAN,tr|H0YJ97|H0YJ97_HUMAN" 2 1073.5353 0.63 93727 4564 2 1073.535485 537.7749 Thyroid receptor-interacting protein 11 OS=Homo sapiens OX=9606 GN=TRIP11 PE=1 SV=3 4.37 1416.3 - 1.62E+06 - - - 0.1695 - 1.408 0.305 - 108.8 1 2 0 0.0002 9 0 0 0 3.37E+07 5.31E+07 - - - 2.2836 0.9722 221125_WJC_METTL3_EV_vs_WT_F07.04568.04568.2 1.47 14-May K.YHPDEVGK[136.11].R sp|Q9BXP5|SRRT_HUMAN 1 951.4541 1.76 93730 4568 2 951.453172 476.7343 Serrate RNA effector molecule homolog OS=Homo sapiens OX=9606 GN=SRRT PE=1 SV=1 5.32 1416.7 - 606539 - - - -1.0237 - 1.014 0.151 - 119.4 2 2 0 -0.001 8 0 0 0 2.29E+07 1.30E+07 - - - 0.0634 0.9783 221125_WJC_METTL3_EV_vs_WT_F07.04569.04569.2 2.40E-05 18-Oct E.AEAAAVHGAR[166.11].F "sp|Q5T8P6|RBM26_HUMAN,tr|E2PSN0|E2PSN0_HUMAN,tr|A0A087X0H9|A0A087X0H9_HUMAN" 3 961.4969 2.13 93731 4569 2 961.498808 481.7557 RNA-binding protein 26 OS=Homo sapiens OX=9606 GN=RBM26 PE=1 SV=3 6.79 1416.8 - 322119 - - - 1.9875 - 2.303 0.41 - 526.6 1 1 0 0.0019 10 0 0 0 1.68E+07 7.86E+06 - - - 4.3972 0.9394 221125_WJC_METTL3_EV_vs_WT_F07.04574.04574.2 1.31 14-Jun K.YHPDEVGK.R sp|Q9BXP5|SRRT_HUMAN 1 943.4399 1.75 93734 4574 2 943.438274 472.7272 Serrate RNA effector molecule homolog OS=Homo sapiens OX=9606 GN=SRRT PE=1 SV=1 5.32 1417.4 - 766866 - - - -1.7722 - 0.932 0.134 - 152.5 1 2 0 -0.0017 8 0 0 0 2.29E+07 1.31E+07 - - - -0.1822 0.9326 221125_WJC_METTL3_EV_vs_WT_F07.04578.04578.2 0.939 14-Jul K.QC[160.03]EDVFC[160.03]K[136.11].H sp|Q96MR9|ZN560_HUMAN 1 1092.446 0.1 93735 4578 2 1092.449375 547.2303 Zinc finger protein 560 OS=Homo sapiens OX=9606 GN=ZNF560 PE=2 SV=2 4.37 1418 - 1.89E+06 - - - 3.1205 - 1.167 0.119 - 198.1 1 2 0 0.0034 8 0 0 0 4.41E+06 4.62E+07 - - - 0.3846 0.9539 221125_WJC_METTL3_EV_vs_WT_F07.04581.04581.2 9.41 14-Jun K.DIVVASNK[136.11].V "sp|O43379|WDR62_HUMAN,tr|A0A7P0T9T4|A0A7P0T9T4_HUMAN,tr|A0A7P0T8U8|A0A7P0T8U8_HUMAN,tr|A0A7P0T972|A0A7P0T972_HUMAN,tr|A0A7P0T8R7|A0A7P0T8R7_HUMAN,tr|A0A7P0TAH3|A0A7P0TAH3_HUMAN,tr|A0A7P0TAK3|A0A7P0TAK3_HUMAN,tr|A0A7P0T9G3|A0A7P0T9G3_HUMAN,tr|A0A2R8YD43|A0A2R8YD43_HUMAN,tr|A0A7P0T9D9|A0A7P0T9D9_HUMAN,tr|A0A7P0T9F6|A0A7P0T9F6_HUMAN,tr|A0A7P0TBE7|A0A7P0TBE7_HUMAN,tr|A0A7P0Z436|A0A7P0Z436_HUMAN,tr|H7C3R4|H7C3R4_HUMAN" 14 852.4796 50.95 93738 4581 2 852.479668 427.2471 WD repeat-containing protein 62 OS=Homo sapiens OX=9606 GN=WDR62 PE=1 SV=4 5.84 1418.3 - 469518 - - - 0.0422 - 1.113 0.11 - 91.8 18 2 0 0 8 0 0 0 4.71E+08 9.24E+06 - - - -0.3844 0.9995 221125_WJC_METTL3_EV_vs_WT_F07.04584.04584.2 0.000388 14-Nov K.HVAEDLGK[136.11].V "sp|P40939|ECHA_HUMAN,tr|H0YFD6|H0YFD6_HUMAN,tr|A0A2R8Y4F5|A0A2R8Y4F5_HUMAN" 3 875.4592 0.97 93739 4584 2 875.456556 438.7369 "Trifunctional enzyme subunit alpha, mitochondrial OS=Homo sapiens OX=9606 GN=HADHA PE=1 SV=2" 5.32 1418.7 - 1.79E+06 - - - -3.0555 - 2.003 0.528 - 444.5 1 2 0 -0.0027 8 0 0 0 8.14E+07 8.42E+07 - - - 5.035 0.9963 221125_WJC_METTL3_EV_vs_WT_F07.04585.04585.2 0.0066 18-Nov K.QPQPSPAEGR.A "sp|P56192|SYMC_HUMAN,tr|H0YHV5|H0YHV5_HUMAN" 2 1065.5203 1.61 93740 4585 2 1065.515515 533.7674 "Methionine--tRNA ligase, cytoplasmic OS=Homo sapiens OX=9606 GN=MARS1 PE=1 SV=2" 6 1418.8 - 1.20E+06 - - - -4.5114 - 1.811 0.404 - 391.6 1 2 0 -0.0048 10 0 0 0 1.10E+08 6.87E+07 - - - 3.6811 0.8431 221125_WJC_METTL3_EV_vs_WT_F07.04586.04586.2 0.636 12-Sep K.LKEEISK.M "sp|P38646|GRP75_HUMAN,tr|A0A7I2V2S7|A0A7I2V2S7_HUMAN,tr|A0A7I2V2G2|A0A7I2V2G2_HUMAN,tr|A0A7I2V3F7|A0A7I2V3F7_HUMAN,tr|A0A7I2YQB2|A0A7I2YQB2_HUMAN,tr|D6RCD7|D6RCD7_HUMAN" 6 845.4858 0.36 93741 4586 2 845.487089 423.7502 "Stress-70 protein, mitochondrial OS=Homo sapiens OX=9606 GN=HSPA9 PE=1 SV=2" 6.14 1418.8 - 2.62E+06 - - - 1.4844 - 1.722 0.002 - 263 2 2 1 0.0013 7 0 0 0 9.71E+07 2.70E+08 - - - 0.643 0.9335 221125_WJC_METTL3_EV_vs_WT_F07.04591.04591.2 0.389 12-Oct K.ER[166.11]EEEFK[136.11].T "sp|Q9NYF8|BCLF1_HUMAN,tr|H0YF63|H0YF63_HUMAN,tr|E9PK91|E9PK91_HUMAN,tr|H0YF14|H0YF14_HUMAN" 4 983.4679 2.1 93744 4591 2 983.466711 492.7412 Bcl-2-associated transcription factor 1 OS=Homo sapiens OX=9606 GN=BCLAF1 PE=1 SV=2 4.49 1419.4 - 4.56E+06 - - - -1.2039 - 1.483 0.114 - 552.2 1 2 1 -0.0012 7 0 0 0 2.59E+09 1.23E+09 - - - 1.1313 0.9913 221125_WJC_METTL3_EV_vs_WT_F07.04597.04597.2 0.104 12-Sep K.EREEEFK.T "sp|Q9NYF8|BCLF1_HUMAN,tr|H0YF63|H0YF63_HUMAN,tr|E9PK91|E9PK91_HUMAN,tr|H0YF14|H0YF14_HUMAN" 4 965.4454 2.1 93748 4597 2 965.444701 483.73 Bcl-2-associated transcription factor 1 OS=Homo sapiens OX=9606 GN=BCLAF1 PE=1 SV=2 4.49 1420 - 1.38E+07 - - - -0.7499 - 1.574 0.297 - 481.5 1 2 1 -0.0007 7 0 0 0 2.59E+09 1.23E+09 - - - 2.6717 0.8619 221125_WJC_METTL3_EV_vs_WT_F07.04600.04600.2 2.17 18-May R.GADQEYSAFR.V "sp|P42262|GRIA2_HUMAN,tr|D6RDX5|D6RDX5_HUMAN,tr|D6RBV7|D6RBV7_HUMAN" 3 1142.4993 0.3 93750 4600 2 1142.500444 572.2569 Glutamate receptor 2 OS=Homo sapiens OX=9606 GN=GRIA2 PE=1 SV=3 4.37 1420.3 - 379528 - - - 1.0433 - 1.018 0.051 - 32.2 8 2 0 0.0012 10 0 0 0 6.61E+06 2.18E+07 - - - -0.9363 0.9948 221125_WJC_METTL3_EV_vs_WT_F07.04603.04603.2 0.0155 16-Jun R.GNSQYPGAK[136.11].Y "sp|P24928|RPB1_HUMAN,tr|A0A6Q8PGB0|A0A6Q8PGB0_HUMAN" 2 928.4494 14.56 93752 4603 2 928.445916 465.232 DNA-directed RNA polymerase II subunit RPB1 OS=Homo sapiens OX=9606 GN=POLR2A PE=1 SV=2 8.59 1420.6 - 293732 - - - -3.7471 - 1.33 0.387 - 124.2 1 2 0 -0.0035 9 0 0 0 2.13E+08 1.46E+07 - - - 2.7233 0.998 221125_WJC_METTL3_EV_vs_WT_F07.04606.04606.2 0.196 12-Jul K.YNDDIRK.G sp|Q9Y3D6|FIS1_HUMAN 1 922.4508 1.45 93753 4606 2 922.450539 462.2327 Mitochondrial fission 1 protein OS=Homo sapiens OX=9606 GN=FIS1 PE=1 SV=2 5.96 1421 - 5.89E+06 - - - -0.3317 - 1.284 0.265 - 125.3 1 2 0 -0.0003 7 0 0 0 2.26E+08 1.56E+08 - - - 1.7903 0.9995 221125_WJC_METTL3_EV_vs_WT_F07.04615.04615.2 0.00118 14-Sep R.SQAIHQLK[136.11].V "sp|Q15046|SYK_HUMAN,tr|H3BVA8|H3BVA8_HUMAN" 2 931.5331 0.65 93756 4615 2 931.531869 466.7738 Lysine--tRNA ligase OS=Homo sapiens OX=9606 GN=KARS1 PE=1 SV=3 8.49 1422.2 - 1.62E+06 - - - -1.2839 - 1.729 0.362 - 411.9 1 2 0 -0.0012 8 0 0 0 5.27E+07 8.10E+07 - - - 3.3657 0.8685 221125_WJC_METTL3_EV_vs_WT_F07.04624.04624.2 5.45 16-Jun K.AKPVTTNLK.K "sp|Q8N0T1|RBIS_HUMAN,tr|A0A087WWE7|A0A087WWE7_HUMAN,tr|E5RGR5|E5RGR5_HUMAN" 3 970.5811 1.96 93761 4624 2 970.580902 486.2978 Ribosomal biogenesis factor OS=Homo sapiens OX=9606 GN=RBIS PE=1 SV=4 10 1423.1 - 3.35E+06 - - - -0.2359 - 1.002 0.018 - 69.2 4 2 0 -0.0002 9 0 0 0 7.96E+07 4.05E+07 - - - -1.0893 0.999 221125_WJC_METTL3_EV_vs_WT_F07.04628.04628.2 0.00061 18-Sep R.LSEHATAPTR.G "sp|P33316|DUT_HUMAN,tr|H0YNJ9|H0YNJ9_HUMAN,tr|H0YMM5|H0YMM5_HUMAN,tr|A0A0C4DGL3|A0A0C4DGL3_HUMAN,tr|H0YKC5|H0YKC5_HUMAN,tr|H0YKI0|H0YKI0_HUMAN,tr|H0YNW5|H0YNW5_HUMAN" 7 1081.5516 1.45 93763 4628 2 1081.548703 541.7831 "Deoxyuridine 5'-triphosphate nucleotidohydrolase, mitochondrial OS=Homo sapiens OX=9606 GN=DUT PE=1 SV=4" 6.75 1423.6 - 1.16E+06 - - - -2.6989 - 1.879 0.394 - 181.8 1 2 0 -0.0029 10 0 0 0 5.31E+07 3.66E+07 - - - 3.7108 0.9999 221125_WJC_METTL3_EV_vs_WT_F07.04636.04636.2 3.03E-07 22-Dec K.SAVESGQADDER.V sp|P78318|IGBP1_HUMAN 1 1262.5375 1.46 93769 4636 2 1262.539205 632.276 Immunoglobulin-binding protein 1 OS=Homo sapiens OX=9606 GN=IGBP1 PE=1 SV=1 3.92 1424.5 - 539986 - - - 1.36 - 2.603 0.561 - 743 1 2 0 0.0017 12 0 0 0 1.30E+07 8.90E+06 - - - 5.7012 0.9952 221125_WJC_METTL3_EV_vs_WT_F07.04639.04639.2 0.0382 12-Jun K.MTFHSQK.F "sp|P52732|KIF11_HUMAN,tr|A0A7I2V3A9|A0A7I2V3A9_HUMAN" 2 877.4116 2.74 93770 4639 2 877.410413 439.7131 Kinesin-like protein KIF11 OS=Homo sapiens OX=9606 GN=KIF11 PE=1 SV=2 8.52 1424.9 - 6.08E+06 - - - -1.3791 - 1.362 0.188 - 152.8 1 2 0 -0.0012 7 0 0 0 3.57E+08 1.30E+08 - - - 1.4081 0.9996 221125_WJC_METTL3_EV_vs_WT_F07.04644.04644.2 0.0448 14-Nov R.K[136.11]AVVVC[160.03]PK[136.11].D "sp|Q00839|HNRPU_HUMAN,tr|A0A1W2PQL0|A0A1W2PQL0_HUMAN,tr|A0A1W2PPL4|A0A1W2PPL4_HUMAN,tr|A0A1W2PQ74|A0A1W2PQ74_HUMAN,tr|Q5RI18|Q5RI18_HUMAN,tr|A0A1W2PP35|A0A1W2PP35_HUMAN,tr|A0A1W2PPS1|A0A1W2PPS1_HUMAN,tr|A0A1W2PRZ7|A0A1W2PRZ7_HUMAN,tr|A0A1W2PPH7|A0A1W2PPH7_HUMAN,tr|A0A1W2PQD4|A0A1W2PQD4_HUMAN,tr|A0A1W2PP34|A0A1W2PP34_HUMAN,tr|A0A1X7SBS1|A0A1X7SBS1_HUMAN" 12 915.5547 0.93 93773 4644 2 915.553417 458.7846 Heterogeneous nuclear ribonucleoprotein U OS=Homo sapiens OX=9606 GN=HNRNPU PE=1 SV=6 9.31 1425.5 - 1.90E+06 - - - -1.3566 - 1.9 0.351 - 471.5 1 2 0 -0.0012 8 0 0 0 3.54E+08 3.82E+08 - - - 3.5689 0.9996 221125_WJC_METTL3_EV_vs_WT_F07.04645.04645.2 0.0079 14-Jul R.KVFGDGSR.L sp|Q16352|AINX_HUMAN 1 864.4454 1.46 93774 4645 2 864.445216 433.23 Alpha-internexin OS=Homo sapiens OX=9606 GN=INA PE=1 SV=2 8.75 1425.6 - 1.43E+06 - - - -0.1735 - 1.586 0.388 - 199.1 1 2 0 -0.0001 8 0 0 0 3.07E+07 2.09E+07 - - - 3.2977 0.9659 221125_WJC_METTL3_EV_vs_WT_F07.04646.04646.2 2.81 16-Jul R.EEVNDRPVR.R "sp|Q9Y520|PRC2C_HUMAN,tr|E7EPN9|E7EPN9_HUMAN" 2 1112.5574 1.44 93775 4646 2 1112.557681 557.286 Protein PRRC2C OS=Homo sapiens OX=9606 GN=PRRC2C PE=1 SV=4 4.68 1425.7 - 918761 - - - 0.2211 - 1.151 0.08 - 82.8 3 2 0 0.0002 9 0 0 0 2.03E+07 1.42E+07 - - - -0.1745 0.9978 221125_WJC_METTL3_EV_vs_WT_F07.04649.04649.2 1.4 18-Aug R.GPPGPESQSR.A "sp|Q9HCD5|NCOA5_HUMAN,tr|Q5JY17|Q5JY17_HUMAN" 2 1010.4781 1.86 93776 4649 2 1010.47628 506.2463 Nuclear receptor coactivator 5 OS=Homo sapiens OX=9606 GN=NCOA5 PE=1 SV=2 6 1426 - 1.15E+07 - - - -1.8229 - 1.562 0.263 - 180.8 1 2 0 -0.0018 10 0 0 0 8.91E+08 4.78E+08 - - - 2.2278 0.9961 221125_WJC_METTL3_EV_vs_WT_F07.04650.04650.2 0.394 16-Aug K.VAEIEHAEK.E "sp|P78371|TCPB_HUMAN,tr|F8VQ14|F8VQ14_HUMAN,tr|F5GWF6|F5GWF6_HUMAN" 3 1024.5189 0.36 93777 4650 2 1024.521401 513.2667 T-complex protein 1 subunit beta OS=Homo sapiens OX=9606 GN=CCT2 PE=1 SV=4 4.75 1426.1 - 1.22E+06 - - - 2.4167 - 1.697 0.216 - 186.8 1 2 0 0.0025 9 0 0 0 2.95E+07 8.17E+07 - - - 2.1656 0.9571 221125_WJC_METTL3_EV_vs_WT_F07.04654.04654.2 7.77 12-May K.KAEAAHR.L "sp|Q9Y618|NCOR2_HUMAN,tr|C9JQE8|C9JQE8_HUMAN,tr|C9JE98|C9JE98_HUMAN,tr|H0YGK8|H0YGK8_HUMAN,tr|C9J330|C9J330_HUMAN,tr|C9J0Q5|C9J0Q5_HUMAN" 6 781.4195 4.67 93779 4654 2 781.41884 391.717 Nuclear receptor corepressor 2 OS=Homo sapiens OX=9606 GN=NCOR2 PE=1 SV=3 8.75 1426.6 - 2.48E+06 - - - -0.8254 - 1.077 0.062 - 100.4 1 2 0 -0.0006 7 0 0 0 1.31E+08 2.80E+07 - - - -0.2662 0.999 221125_WJC_METTL3_EV_vs_WT_F07.04656.04656.2 0.0181 14-Oct R.KAVVVC[160.03]PK.D "sp|Q00839|HNRPU_HUMAN,tr|A0A1W2PQL0|A0A1W2PQL0_HUMAN,tr|A0A1W2PPL4|A0A1W2PPL4_HUMAN,tr|A0A1W2PQ74|A0A1W2PQ74_HUMAN,tr|Q5RI18|Q5RI18_HUMAN,tr|A0A1W2PP35|A0A1W2PP35_HUMAN,tr|A0A1W2PPS1|A0A1W2PPS1_HUMAN,tr|A0A1W2PRZ7|A0A1W2PRZ7_HUMAN,tr|A0A1W2PPH7|A0A1W2PPH7_HUMAN,tr|A0A1W2PQD4|A0A1W2PQD4_HUMAN,tr|A0A1W2PP34|A0A1W2PP34_HUMAN,tr|A0A1X7SBS1|A0A1X7SBS1_HUMAN" 12 899.5263 0.93 93781 4656 2 899.525635 450.7704 Heterogeneous nuclear ribonucleoprotein U OS=Homo sapiens OX=9606 GN=HNRNPU PE=1 SV=6 9.31 1426.8 - 3.08E+06 - - - -0.6937 - 1.76 0.225 - 402.4 1 2 0 -0.0006 8 0 0 0 3.54E+08 3.82E+08 - - - 2.4076 0.9993 221125_WJC_METTL3_EV_vs_WT_F07.04657.04657.3 0.0168 13/44 K.LLGSAGSNK[136.11]EEK[136.11].G "sp|O60524|NEMF_HUMAN,tr|G3V5V3|G3V5V3_HUMAN" 2 1247.6692 0.79 93782 4657 3 1247.668227 416.897 Nuclear export mediator factor NEMF OS=Homo sapiens OX=9606 GN=NEMF PE=1 SV=4 6.14 1426.8 - 2.38E+06 - - - -0.8047 - 2.421 0.346 - 242.8 1 2 1 -0.001 12 0 0 0 2.79E+07 3.51E+07 - - - 4.8481 0.9973 221125_WJC_METTL3_EV_vs_WT_F07.04658.04658.3 0.0158 Dec-44 K.LLGSAGSNKEEK.G "sp|O60524|NEMF_HUMAN,tr|G3V5V3|G3V5V3_HUMAN" 2 1231.6408 0.79 93783 4658 3 1231.639565 411.5542 Nuclear export mediator factor NEMF OS=Homo sapiens OX=9606 GN=NEMF PE=1 SV=4 6.14 1426.9 - 2.00E+06 - - - -1.0279 - 1.73 0.328 - 135.9 1 2 1 -0.0013 12 0 0 0 2.79E+07 3.51E+07 - - - 3.7158 0.9977 221125_WJC_METTL3_EV_vs_WT_F07.04659.04659.2 0.0846 14-Sep R.SQAIHQLK.V "sp|Q15046|SYK_HUMAN,tr|H3BVA8|H3BVA8_HUMAN" 2 923.5189 0.65 93784 4659 2 923.517559 462.7667 Lysine--tRNA ligase OS=Homo sapiens OX=9606 GN=KARS1 PE=1 SV=3 8.49 1426.9 - 1.88E+06 - - - -1.4142 - 1.538 0.226 - 285.3 1 2 0 -0.0013 8 0 0 0 5.27E+07 8.09E+07 - - - 2.0081 0.9992 221125_WJC_METTL3_EV_vs_WT_F07.04660.04660.2 0.000847 20-Sep R.SGPQSASTAVK[136.11].E sp|Q9BTC0|DIDO1_HUMAN 1 1039.5389 2.43 93785 4660 2 1039.537931 520.7767 Death-inducer obliterator 1 OS=Homo sapiens OX=9606 GN=DIDO1 PE=1 SV=5 8.47 1427 - 843490 - - - -0.9687 - 1.468 0.361 - 215.9 1 2 0 -0.001 11 0 0 0 6.51E+07 2.68E+07 - - - 2.7456 0.9413 221125_WJC_METTL3_EV_vs_WT_F07.04661.04661.2 0.235 14-Oct K.LREQVEER.L "sp|O00567|NOP56_HUMAN,tr|A0A494C128|A0A494C128_HUMAN,tr|H0YDU4|H0YDU4_HUMAN,tr|H0Y653|H0Y653_HUMAN" 4 1057.5516 1.23 93786 4661 2 1057.551011 529.7831 Nucleolar protein 56 OS=Homo sapiens OX=9606 GN=NOP56 PE=1 SV=4 4.79 1427.1 - 770357 - - - -0.5777 - 1.883 0.015 - 239.5 1 2 1 -0.0006 8 0 0 0 1.10E+07 8.96E+06 - - - 1.0603 0.9996 221125_WJC_METTL3_EV_vs_WT_F07.04665.04665.2 0.432 16-Sep K.VAEIEHAEK[136.11].E "sp|P78371|TCPB_HUMAN,tr|F8VQ14|F8VQ14_HUMAN,tr|F5GWF6|F5GWF6_HUMAN" 3 1032.5331 0.37 93788 4665 2 1032.531903 517.2738 T-complex protein 1 subunit beta OS=Homo sapiens OX=9606 GN=CCT2 PE=1 SV=4 4.75 1427.5 - 5.30E+06 - - - -1.1835 - 1.969 0.366 - 300.7 1 2 0 -0.0012 9 0 0 0 2.91E+07 7.82E+07 - - - 3.704 0.9948 221125_WJC_METTL3_EV_vs_WT_F07.04666.04666.2 0.0581 18-Sep K.IK[136.11]EGVEEAAK[136.11].T "sp|O43615|TIM44_HUMAN,tr|M0QXU7|M0QXU7_HUMAN" 2 1088.6048 1.09 93789 4666 2 1088.60453 545.3097 Mitochondrial import inner membrane translocase subunit TIM44 OS=Homo sapiens OX=9606 GN=TIMM44 PE=1 SV=2 4.79 1427.6 - 3.64E+06 - - - -0.2848 - 1.791 0.327 - 147.1 1 2 1 -0.0003 10 0 0 0 5.15E+07 4.74E+07 - - - 3.0828 0.9969 221125_WJC_METTL3_EV_vs_WT_F07.04667.04667.2 0.0123 18-Oct K.IKEGVEEAAK.T "sp|O43615|TIM44_HUMAN,tr|M0QXU7|M0QXU7_HUMAN" 2 1072.5764 1.09 93790 4667 2 1072.576248 537.2955 Mitochondrial import inner membrane translocase subunit TIM44 OS=Homo sapiens OX=9606 GN=TIMM44 PE=1 SV=2 4.79 1427.6 - 3.51E+06 - - - -0.179 - 2.073 0.349 - 193.7 1 2 1 -0.0002 10 0 0 0 5.15E+07 4.74E+07 - - - 3.6535 0.9917 221125_WJC_METTL3_EV_vs_WT_F07.04670.04670.2 0.00625 22-Jul K.LLGSAGSNK[136.11]EEK[136.11].G "sp|O60524|NEMF_HUMAN,tr|G3V5V3|G3V5V3_HUMAN" 2 1247.6692 0.65 93793 4670 2 1247.667282 624.8419 Nuclear export mediator factor NEMF OS=Homo sapiens OX=9606 GN=NEMF PE=1 SV=4 6.14 1428 - 362734 - - - -1.5621 - 1.6 0.383 - 118.9 1 2 1 -0.0019 12 0 0 0 2.60E+06 4.00E+06 - - - 3.1059 0.9932 221125_WJC_METTL3_EV_vs_WT_F07.04671.04671.2 0.0284 18-Jul K.EK[136.11]PVC[160.03]GTTYK[136.11].V "sp|Q14444|CAPR1_HUMAN,tr|G3V153|G3V153_HUMAN" 2 1197.6035 0.29 93794 4671 2 1197.607513 599.809 Caprin-1 OS=Homo sapiens OX=9606 GN=CAPRIN1 PE=1 SV=2 8.27 1428.1 - 338617 - - - 3.3843 - 1.26 0.35 - 104.5 1 2 0 0.0041 10 0 0 0 3.91E+06 1.33E+07 - - - 2.2699 0.9744 221125_WJC_METTL3_EV_vs_WT_F07.04672.04672.2 0.0221 22-Aug K.LLGSAGSNKEEK.G "sp|O60524|NEMF_HUMAN,tr|G3V5V3|G3V5V3_HUMAN" 2 1231.6408 0.65 93795 4672 2 1231.643359 616.8277 Nuclear export mediator factor NEMF OS=Homo sapiens OX=9606 GN=NEMF PE=1 SV=4 6.14 1428.2 - 245129 - - - 2.0525 - 1.338 0.35 - 162.4 1 2 1 0.0025 12 0 0 0 2.60E+06 4.00E+06 - - - 2.3914 0.9998 221125_WJC_METTL3_EV_vs_WT_F07.04676.04676.2 5.19E-07 20-Nov K.GTEISSGAASK.N sp|Q9HCJ3|RAVR2_HUMAN 1 1006.4931 1.5 93797 4676 2 1006.493001 504.2538 Ribonucleoprotein PTB-binding 2 OS=Homo sapiens OX=9606 GN=RAVER2 PE=1 SV=2 6 1428.8 - 6.77E+06 - - - -0.1023 - 2.26 0.346 - 525.4 1 2 0 -0.0001 11 0 0 0 1.94E+08 1.30E+08 - - - 3.8023 0.9993 221125_WJC_METTL3_EV_vs_WT_F07.04677.04677.2 1.11 20-Nov K.GTEISSGAASK[136.11].N sp|Q9HCJ3|RAVR2_HUMAN 1 1014.5073 1.5 93798 4677 2 1014.509948 508.2609 Ribonucleoprotein PTB-binding 2 OS=Homo sapiens OX=9606 GN=RAVER2 PE=1 SV=2 6 1428.8 - 4.68E+06 - - - 2.6062 - 2.241 0.374 - 567.7 1 2 0 0.0026 11 0 0 0 1.95E+08 1.30E+08 - - - 3.9854 0.9998 221125_WJC_METTL3_EV_vs_WT_F07.04678.04678.2 0.00579 20-Nov R.APAVQGADNQR.A sp|Q9H0W5|CCDC8_HUMAN 1 1125.5527 1.31 93799 4678 2 1125.552488 563.7836 Coiled-coil domain-containing protein 8 OS=Homo sapiens OX=9606 GN=CCDC8 PE=1 SV=2 5.88 1428.9 - 2.20E+06 - - - -0.1741 - 2.174 0.394 - 491.1 1 2 0 -0.0002 11 0 0 0 1.08E+08 8.23E+07 - - - 4.0518 0.9999 221125_WJC_METTL3_EV_vs_WT_F07.04680.04680.2 0.001 20-Dec R.APAVQGADNQR[166.11].A sp|Q9H0W5|CCDC8_HUMAN 1 1135.561 1.31 93801 4680 2 1135.560528 568.7878 Coiled-coil domain-containing protein 8 OS=Homo sapiens OX=9606 GN=CCDC8 PE=1 SV=2 5.88 1429 - 1.34E+06 - - - -0.3751 - 2.317 0.539 - 651.1 1 2 0 -0.0004 11 0 0 0 1.08E+08 8.23E+07 - - - 5.2951 0.9981 221125_WJC_METTL3_EV_vs_WT_F07.04681.04681.3 0.0447 Oct-36 K.DAENHEAQLK[136.11].N "sp|Q9Y266|NUDC_HUMAN,tr|A0A0A0MSS4|A0A0A0MSS4_HUMAN,tr|A0A0A0MSU9|A0A0A0MSU9_HUMAN" 3 1161.5506 1.99 93802 4681 3 1161.549267 388.1908 Nuclear migration protein nudC OS=Homo sapiens OX=9606 GN=NUDC PE=1 SV=1 4.65 1429.1 - 1.30E+06 - - - -1.1183 - 1.737 0.246 - 129 1 2 0 -0.0013 10 0 0 0 1.08E+08 5.40E+07 - - - 2.8948 1 221125_WJC_METTL3_EV_vs_WT_F07.04686.04686.2 1.18E-08 20-Dec R.LENNENKPVTN.S sp|Q9Y5A9|YTHD2_HUMAN 1 1270.6153 1.63 93807 4686 2 1270.612679 636.3149 YTH domain-containing family protein 2 OS=Homo sapiens OX=9606 GN=YTHDF2 PE=1 SV=2 4.53 1429.6 - 298903 - - - -2.0974 - 2.717 0.579 - 621 1 1 0 -0.0027 11 0 0 0 4.61E+07 2.83E+07 - - - 6.0206 0.9999 221125_WJC_METTL3_EV_vs_WT_F07.04690.04690.2 0.000362 13/16 R.HIAAEEVSK.E sp|O60318|GANP_HUMAN 1 982.5084 2.61 93809 4690 2 982.507919 492.2615 Germinal-center associated nuclear protein OS=Homo sapiens OX=9606 GN=MCM3AP PE=1 SV=2 5.4 1430 - 2.79E+06 - - - -0.4489 - 2.112 0.452 - 607.3 1 2 0 -0.0004 9 0 0 0 1.04E+08 3.97E+07 - - - 4.5423 0.9992 221125_WJC_METTL3_EV_vs_WT_F07.04701.04701.2 0.0288 12-Jul K.MTFHSQK[136.11].F "sp|P52732|KIF11_HUMAN,tr|A0A7I2V3A9|A0A7I2V3A9_HUMAN" 2 885.4258 3.42 93817 4701 2 885.425679 443.7202 Kinesin-like protein KIF11 OS=Homo sapiens OX=9606 GN=KIF11 PE=1 SV=2 8.52 1431.3 - 2.13E+06 - - - -0.1626 - 1.396 0.335 - 222.2 1 2 0 -0.0001 7 0 0 0 3.42E+08 1.00E+08 - - - 2.5723 0.9961 221125_WJC_METTL3_EV_vs_WT_F07.04702.04702.2 2.58 16-Aug K.EIEVGGGRK.A "sp|P62081|RS7_HUMAN,tr|B5MCP9|B5MCP9_HUMAN" 2 943.5087 0.83 93818 4702 2 943.507248 472.7616 40S ribosomal protein S7 OS=Homo sapiens OX=9606 GN=RPS7 PE=1 SV=1 6.24 1431.3 - 2.29E+06 - - - -1.5326 - 1.561 0.177 - 271 1 2 0 -0.0014 9 0 0 0 1.79E+08 2.17E+08 - - - 1.6362 0.9992 221125_WJC_METTL3_EV_vs_WT_F07.04704.04704.2 0.0464 18-Jul R.QSETC[160.03]SPGSD.- "sp|P31025|LCN1_HUMAN,sp|Q5VSP4|LC1L1_HUMAN" 2 1066.3873 - 93820 4704 2 1066.387652 534.2009 Lipocalin-1 OS=Homo sapiens OX=9606 GN=LCN1 PE=1 SV=1 4.03 1431.5 - 1.56E+06 - - - 0.3132 - 1.014 0.481 - 155.7 1 2 0 0.0003 10 0 0 0 - - - - - 2.6324 0.9945 221125_WJC_METTL3_EV_vs_WT_F07.04705.04705.2 0.000101 20-Oct R.LENNENK[136.11]PVTN.S sp|Q9Y5A9|YTHD2_HUMAN 1 1278.6295 1.63 93821 4705 2 1278.629015 640.322 YTH domain-containing family protein 2 OS=Homo sapiens OX=9606 GN=YTHDF2 PE=1 SV=2 4.53 1431.6 - 1.43E+06 - - - -0.4137 - 2.444 0.538 - 354.7 1 1 0 -0.0005 11 0 0 0 4.61E+07 2.83E+07 - - - 5.432 0.9981 221125_WJC_METTL3_EV_vs_WT_F07.04706.04706.2 0.733 14-Jun R.QQQEQIAR.Q "sp|P35712|SOX6_HUMAN,sp|P35711|SOX5_HUMAN,tr|F5H0I3|F5H0I3_HUMAN,tr|I3L0A5|I3L0A5_HUMAN" 4 999.5098 3.39 93822 4706 2 999.50956 500.7622 Transcription factor SOX-6 OS=Homo sapiens OX=9606 GN=SOX6 PE=1 SV=3 6 1431.7 - 1.12E+06 - - - -0.1971 - 1.475 0.22 - 179.8 1 2 0 -0.0002 8 0 0 0 3.79E+07 1.12E+07 - - - 1.838 0.9978 221125_WJC_METTL3_EV_vs_WT_F07.04707.04707.3 0.207 Sep-36 R.INVVNNHQAK[136.11].Q "sp|Q9BY77|PDIP3_HUMAN,tr|F6VRR5|F6VRR5_HUMAN,tr|F8WCX5|F8WCX5_HUMAN" 3 1143.624 0.07 93823 4707 3 1143.622358 382.2153 Polymerase delta-interacting protein 3 OS=Homo sapiens OX=9606 GN=POLDIP3 PE=1 SV=2 8.76 1431.7 - 815167 - - - -1.4402 - 1.874 0.229 - 74.8 1 2 0 -0.0016 10 0 0 0 6.91E+07 1.04E+09 - - - 2.9269 0.9805 221125_WJC_METTL3_EV_vs_WT_F07.04714.04714.2 0.419 16-Jun K.EIEVGGGR[166.11]K[136.11].A "sp|P62081|RS7_HUMAN,tr|B5MCP9|B5MCP9_HUMAN" 2 961.5312 0.83 93828 4714 2 961.530388 481.7729 40S ribosomal protein S7 OS=Homo sapiens OX=9606 GN=RPS7 PE=1 SV=1 6.24 1432.6 - 9.96E+06 - - - -0.807 - 1.32 0.083 - 111.8 3 2 0 -0.0008 9 0 0 0 1.79E+08 2.17E+08 - - - 0.2439 0.9381 221125_WJC_METTL3_EV_vs_WT_F07.04717.04717.2 0.173 18-Dec T.TVHAITATQK[136.11].T "sp|P04406|G3P_HUMAN,tr|E7EUT5|E7EUT5_HUMAN" 2 1076.607 0.77 93831 4717 2 1076.606623 539.3108 Glyceraldehyde-3-phosphate dehydrogenase OS=Homo sapiens OX=9606 GN=GAPDH PE=1 SV=3 8.44 1432.7 - 1.08E+06 - - - -0.3112 - 1.866 0.204 - 508.3 1 1 0 -0.0003 10 0 0 0 8.46E+06 1.10E+07 - - - 2.2888 0.9998 221125_WJC_METTL3_EV_vs_WT_F07.04720.04720.2 0.0168 16-Nov K.VDDYEHAAK.Y "sp|O43148|MCES_HUMAN,tr|K7EP06|K7EP06_HUMAN,tr|K7ERH6|K7ERH6_HUMAN" 3 1046.4669 1.44 93834 4720 2 1046.466309 524.2407 mRNA cap guanine-N7 methyltransferase OS=Homo sapiens OX=9606 GN=RNMT PE=1 SV=1 4.54 1433 - 878358 - - - -0.5542 - 2.114 0.409 - 522.7 1 2 0 -0.0006 9 0 0 0 3.26E+07 2.26E+07 - - - 4.2274 0.9994 221125_WJC_METTL3_EV_vs_WT_F07.04724.04724.2 0.0385 18-Nov R.INVVNNHQAK[136.11].Q "sp|Q9BY77|PDIP3_HUMAN,tr|F6VRR5|F6VRR5_HUMAN,tr|F8WCX5|F8WCX5_HUMAN" 3 1143.624 1.37 93836 4724 2 1143.622736 572.8193 Polymerase delta-interacting protein 3 OS=Homo sapiens OX=9606 GN=POLDIP3 PE=1 SV=2 8.76 1433.5 - 2.48E+06 - - - -1.1096 - 2.1 0.274 - 434.8 1 2 0 -0.0013 10 0 0 0 2.51E+08 1.83E+08 - - - 3.1353 0.9958 221125_WJC_METTL3_EV_vs_WT_F07.04726.04726.2 0.04 14-Aug R.QSVSGLHR.Y "sp|Q8N1G4|LRC47_HUMAN,tr|J3KRP5|J3KRP5_HUMAN" 2 882.4672 0.77 93838 4726 2 882.465802 442.2409 Leucine-rich repeat-containing protein 47 OS=Homo sapiens OX=9606 GN=LRRC47 PE=1 SV=1 9.76 1433.6 - 872344 - - - -1.5434 - 1.409 0.202 - 319 1 2 0 -0.0014 8 0 0 0 2.04E+07 2.67E+07 - - - 1.5667 0.9538 221125_WJC_METTL3_EV_vs_WT_F07.04727.04727.2 2.28 12-Jun R.GQSHWVK[136.11].R "sp|Q96EE3|SEH1_HUMAN,tr|K7EP88|K7EP88_HUMAN,tr|K7ELV2|K7ELV2_HUMAN" 3 848.4384 0.8 93839 4727 2 848.436936 425.2265 Nucleoporin SEH1 OS=Homo sapiens OX=9606 GN=SEH1L PE=1 SV=3 8.76 1433.7 - 514895 - - - -1.768 - 1.02 0.121 - 117.7 1 2 0 -0.0015 7 0 0 0 1.16E+07 1.46E+07 - - - -0.003 0.9998 221125_WJC_METTL3_EV_vs_WT_F07.04728.04728.2 2.00E-06 24-Dec R.GDTGGEDTAAPGR[166.11].F sp|Q9H773|DCTP1_HUMAN 1 1212.5246 0.56 93840 4728 2 1212.522368 607.2696 dCTP pyrophosphatase 1 OS=Homo sapiens OX=9606 GN=DCTPP1 PE=1 SV=1 4.03 1433.9 - 183322 - - - -1.8639 - 2.257 0.539 - 310.6 1 2 0 -0.0023 13 0 0 0 4.55E+06 8.12E+06 - - - 5.1106 0.9996 221125_WJC_METTL3_EV_vs_WT_F07.04731.04731.2 0.00116 18-Oct R.INVVNNHQAK.Q "sp|Q9BY77|PDIP3_HUMAN,tr|F6VRR5|F6VRR5_HUMAN,tr|F8WCX5|F8WCX5_HUMAN" 3 1135.6098 1.37 93841 4731 2 1135.608951 568.8122 Polymerase delta-interacting protein 3 OS=Homo sapiens OX=9606 GN=POLDIP3 PE=1 SV=2 8.76 1434.3 - 6.05E+06 - - - -0.752 - 1.864 0.361 - 303.2 1 2 0 -0.0009 10 0 0 0 2.51E+08 1.83E+08 - - - 3.4453 0.9995 221125_WJC_METTL3_EV_vs_WT_F07.04732.04732.2 0.000198 20-Nov K.ASVEDADTQSK[136.11].V "sp|Q13561|DCTN2_HUMAN,tr|H0YI98|H0YI98_HUMAN,tr|A8K8J9|A8K8J9_HUMAN,tr|F8W1I6|F8W1I6_HUMAN,tr|A0A7I2V4H4|A0A7I2V4H4_HUMAN,tr|A0A7I2V4Y9|A0A7I2V4Y9_HUMAN" 6 1157.5292 2.72 93842 4732 2 1157.5261 579.7719 Dynactin subunit 2 OS=Homo sapiens OX=9606 GN=DCTN2 PE=1 SV=4 4.03 1434.3 - 1.50E+06 - - - -2.6444 - 2.109 0.487 - 411.1 1 2 0 -0.0031 11 0 0 0 1.70E+08 6.24E+07 - - - 4.6557 0.9295 221125_WJC_METTL3_EV_vs_WT_F07.04733.04733.2 0.04 16-Jul A.HVEYSTAAR.H sp|P49411|EFTU_HUMAN 1 1032.4989 1.16 93843 4733 2 1032.498778 517.2567 "Elongation factor Tu, mitochondrial OS=Homo sapiens OX=9606 GN=TUFM PE=1 SV=2" 6.75 1434.4 - 3.37E+06 - - - -0.0775 - 1.226 0.343 - 158.7 1 1 0 -0.0001 9 0 0 0 4.62E+07 3.99E+07 - - - 2.1639 0.9442 221125_WJC_METTL3_EV_vs_WT_F07.04734.04734.2 0.00875 16-Aug L.NVVNNHQAK.Q "sp|Q9BY77|PDIP3_HUMAN,tr|F6VRR5|F6VRR5_HUMAN,tr|F8WCX5|F8WCX5_HUMAN" 3 1022.5257 1.59 93844 4734 2 1022.523648 512.2701 Polymerase delta-interacting protein 3 OS=Homo sapiens OX=9606 GN=POLDIP3 PE=1 SV=2 8.76 1434.4 - 3.34E+06 - - - -2.0469 - 1.447 0.412 - 168.5 1 1 0 -0.0021 9 0 0 0 1.24E+08 7.80E+07 - - - 3.1523 0.7907 221125_WJC_METTL3_EV_vs_WT_F07.04736.04736.2 0.076 14-Jul N.VVNNHQAK.Q "sp|Q9BY77|PDIP3_HUMAN,tr|F6VRR5|F6VRR5_HUMAN,tr|F8WCX5|F8WCX5_HUMAN" 3 908.4828 0.56 93846 4736 2 908.482585 455.2487 Polymerase delta-interacting protein 3 OS=Homo sapiens OX=9606 GN=POLDIP3 PE=1 SV=2 8.73 1434.6 - 1.11E+06 - - - -0.2521 - 1.227 0.208 - 124 1 1 0 -0.0002 8 0 0 0 3.81E+07 6.82E+07 - - - 1.1942 0.8246 221125_WJC_METTL3_EV_vs_WT_F07.04740.04740.2 3.95 16-Apr K.GLEGER[166.11]PAR[166.11].L "sp|P46783|RS10_HUMAN,tr|A0A2R8Y6L3|A0A2R8Y6L3_HUMAN,tr|F6U211|F6U211_HUMAN,tr|A0A1W2PQS6|A0A1W2PQS6_HUMAN,tr|A0A2R8YFH6|A0A2R8YFH6_HUMAN,tr|A0A2R8Y7H1|A0A2R8Y7H1_HUMAN,tr|S4R435|S4R435_HUMAN" 7 1003.5314 1.48 93848 4740 2 1003.530294 502.773 40S ribosomal protein S10 OS=Homo sapiens OX=9606 GN=RPS10 PE=1 SV=1 6.14 1435.1 - 5.91E+06 - - - -1.0842 - 0.933 0.089 - 26.3 30 2 0 -0.0011 9 0 0 0 2.33E+08 1.58E+08 - - - -1.1625 0.9993 221125_WJC_METTL3_EV_vs_WT_F07.04746.04746.2 0.00231 20-Jul K.IQQQQPPPGEK[136.11].K "sp|P26640|SYVC_HUMAN,tr|A0A140T936|A0A140T936_HUMAN,tr|A0A140T954|A0A140T954_HUMAN" 3 1256.6605 0.48 93854 4746 2 1256.661863 629.3375 Valine--tRNA ligase OS=Homo sapiens OX=9606 GN=VARS1 PE=1 SV=4 6 1435.7 - 189461 - - - 1.1244 - 1.531 0.387 - 149.2 1 2 0 0.0014 11 0 0 0 3.59E+06 7.54E+06 - - - 3.0512 0.998 221125_WJC_METTL3_EV_vs_WT_F07.04749.04749.3 0.00534 Oct-36 K.AASLTEDR[166.11]DR[166.11].G "sp|Q04637|IF4G1_HUMAN,tr|E7EUU4|E7EUU4_HUMAN,tr|E9PGM1|E9PGM1_HUMAN,tr|E7EX73|E7EX73_HUMAN,tr|A0A7I2Y1C3|A0A7I2Y1C3_HUMAN" 5 1152.5638 0.001 93855 4749 3 1152.562202 385.1952 Eukaryotic translation initiation factor 4 gamma 1 OS=Homo sapiens OX=9606 GN=EIF4G1 PE=1 SV=4 4.56 1436.1 - 3.19E+06 - - - -1.3908 - 1.859 0.336 - 215.8 1 2 1 -0.0016 10 0 0 0 0.00E+00 5.26E+07 - - - 4.0964 0.9503 221125_WJC_METTL3_EV_vs_WT_F07.04750.04750.2 4.56 14-Jun R.QVHNSFAR[166.11].Q "sp|Q9Y5K5|UCHL5_HUMAN,tr|Q5LJA9|Q5LJA9_HUMAN,tr|H0Y6Y4|H0Y6Y4_HUMAN,tr|Q5LJB0|Q5LJB0_HUMAN,tr|Q5LJA5|Q5LJA5_HUMAN" 5 967.4863 1.81 93856 4750 2 967.48563 484.7504 Ubiquitin carboxyl-terminal hydrolase isozyme L5 OS=Homo sapiens OX=9606 GN=UCHL5 PE=1 SV=3 9.76 1436.1 - 2.28E+06 - - - -0.7266 - 1.005 0.076 - 147.2 1 2 0 -0.0007 8 0 0 0 5.81E+07 3.21E+07 - - - -0.3828 0.9828 221125_WJC_METTL3_EV_vs_WT_F07.04751.04751.2 3.53 12-Jul R.RDSFDDR.G "sp|P43243|MATR3_HUMAN,tr|A8MXP9|A8MXP9_HUMAN,tr|D6R991|D6R991_HUMAN,tr|A0A0R4J2E8|A0A0R4J2E8_HUMAN,tr|D6REM6|D6REM6_HUMAN" 5 909.3941 1.37 93857 4751 2 909.392701 455.7043 Matrin-3 OS=Homo sapiens OX=9606 GN=MATR3 PE=1 SV=2 4.43 1436.2 - 2.48E+06 - - - -1.4922 - 1.241 0.111 - 150.2 1 2 0 -0.0014 7 0 0 0 1.55E+08 1.13E+08 - - - 0.5446 0.7884 221125_WJC_METTL3_EV_vs_WT_F07.04752.04752.2 0.0808 20-Nov M.AKEGVVAAAEK.T "sp|Q16143|SYUB_HUMAN,sp|P37840|SYUA_HUMAN,tr|A0A669KB41|A0A669KB41_HUMAN,tr|G4Y816|G4Y816_HUMAN,tr|D6RA31|D6RA31_HUMAN,tr|A0A669KBH5|A0A669KBH5_HUMAN,tr|H6UYS7|H6UYS7_HUMAN,tr|E7EPV7|E7EPV7_HUMAN" 8 1071.5924 1.74 93858 4752 2 1071.591892 536.8035 Beta-synuclein OS=Homo sapiens OX=9606 GN=SNCB PE=1 SV=1 6.19 1436.3 - 594467 - - - -0.4965 - 1.983 0.324 - 254.5 1 1 1 -0.0005 11 0 0 0 4.35E+08 2.50E+08 - - - 3.2859 0.9998 221125_WJC_METTL3_EV_vs_WT_F07.04753.04753.2 5.20E-06 24-Sep R.GDTGGEDTAAPGR.F sp|Q9H773|DCTP1_HUMAN 1 1202.5164 0.5 93859 4753 2 1202.51458 602.2655 dCTP pyrophosphatase 1 OS=Homo sapiens OX=9606 GN=DCTPP1 PE=1 SV=1 4.03 1436.4 - 411484 - - - -1.4786 - 2.135 0.554 - 217.1 1 2 0 -0.0018 13 0 0 0 4.62E+06 9.33E+06 - - - 5.0789 0.9641 221125_WJC_METTL3_EV_vs_WT_F07.04756.04756.2 0.0742 14-Jun R.KPATSYVR.T "sp|P46779|RL28_HUMAN,tr|H0YKD8|H0YKD8_HUMAN" 2 920.508 1.98 93860 4756 2 920.506739 461.2613 60S ribosomal protein L28 OS=Homo sapiens OX=9606 GN=RPL28 PE=1 SV=3 9.99 1436.8 - 2.67E+06 - - - -1.333 - 1.329 0.031 - 106.2 2 2 0 -0.0012 8 0 0 0 4.02E+07 2.03E+07 - - - -0.0071 0.9989 221125_WJC_METTL3_EV_vs_WT_F07.04757.04757.2 0.979 12-Jul R.R[166.11]DSFDDR[166.11].G "sp|P43243|MATR3_HUMAN,tr|A8MXP9|A8MXP9_HUMAN,tr|D6R991|D6R991_HUMAN,tr|A0A0R4J2E8|A0A0R4J2E8_HUMAN,tr|D6REM6|D6REM6_HUMAN" 5 929.4106 1.37 93861 4757 2 929.408314 465.7126 Matrin-3 OS=Homo sapiens OX=9606 GN=MATR3 PE=1 SV=2 4.43 1436.9 - 2.92E+06 - - - -2.4575 - 1.662 0.36 - 245.9 1 2 0 -0.0023 7 0 0 0 1.55E+08 1.13E+08 - - - 3.3089 0.9998 221125_WJC_METTL3_EV_vs_WT_F07.04762.04762.2 0.00256 14-Oct K.RFTDEESR.V "sp|Q9NYF8|BCLF1_HUMAN,tr|H0YF00|H0YF00_HUMAN,tr|E9PKI6|E9PKI6_HUMAN,tr|A0A1W2PQ43|A0A1W2PQ43_HUMAN,tr|E9PK91|E9PK91_HUMAN,tr|E9PK09|E9PK09_HUMAN,tr|E9PQN2|E9PQN2_HUMAN" 7 1038.473 2.25 93865 4762 2 1038.472535 520.2438 Bcl-2-associated transcription factor 1 OS=Homo sapiens OX=9606 GN=BCLAF1 PE=1 SV=2 4.68 1437.4 - 1.76E+07 - - - -0.4834 - 2.451 0.376 - 327.9 1 2 0 -0.0005 8 0 0 0 1.01E+09 4.50E+08 - - - 4.5218 0.891 221125_WJC_METTL3_EV_vs_WT_F07.04764.04764.2 0.00096 13/20 M.AK[136.11]EGVVAAAEK[136.11].T "sp|Q16143|SYUB_HUMAN,sp|P37840|SYUA_HUMAN,tr|A0A669KB41|A0A669KB41_HUMAN,tr|G4Y816|G4Y816_HUMAN,tr|D6RA31|D6RA31_HUMAN,tr|A0A669KBH5|A0A669KBH5_HUMAN,tr|H6UYS7|H6UYS7_HUMAN,tr|E7EPV7|E7EPV7_HUMAN" 8 1087.6208 1.74 93867 4764 2 1087.622224 544.8177 Beta-synuclein OS=Homo sapiens OX=9606 GN=SNCB PE=1 SV=1 6.19 1437.6 - 1.87E+06 - - - 1.2872 - 2.534 0.451 - 310.6 1 1 1 0.0014 11 0 0 0 4.35E+08 2.50E+08 - - - 4.887 0.9995 221125_WJC_METTL3_EV_vs_WT_F07.04765.04765.2 0.0172 14-Oct R.R[166.11]QQEEMMR[166.11].R "sp|Q15233|NONO_HUMAN,tr|A0A7I2V535|A0A7I2V535_HUMAN,tr|A0A7I2V4K9|A0A7I2V4K9_HUMAN,tr|A0A7P0MRW0|A0A7P0MRW0_HUMAN,tr|H7C367|H7C367_HUMAN,tr|A0A7I2V4J2|A0A7I2V4J2_HUMAN,tr|A0A7I2V5Y7|A0A7I2V5Y7_HUMAN" 7 1126.5126 0.64 93868 4765 2 1126.511684 564.2636 Non-POU domain-containing octamer-binding protein OS=Homo sapiens OX=9606 GN=NONO PE=1 SV=4 6.14 1437.6 - 1.81E+06 - - - -0.846 - 1.545 0.392 - 232.8 1 2 0 -0.001 8 0 0 0 2.59E+07 4.05E+07 - - - 3.248 0.982 221125_WJC_METTL3_EV_vs_WT_F07.04771.04771.3 0.373 Jul-36 K.KDVDSAYMNK.V sp|P12035|K2C3_HUMAN 1 1169.5387 0.03 93872 4771 3 1169.53755 390.8535 "Keratin, type II cytoskeletal 3 OS=Homo sapiens OX=9606 GN=KRT3 PE=1 SV=3" 5.96 1438.2 - 1.11E+06 - - - -0.9611 - 1.412 0.171 - 68.6 1 2 0 -0.0011 10 0 0 0 4.53E+07 1.52E+09 - - - 1.4537 0.9635 221125_WJC_METTL3_EV_vs_WT_F07.04777.04777.2 0.859 18-Sep K.QLENQNPQGR[166.11].Q sp|Q14146|URB2_HUMAN 1 1192.5824 0.58 93876 4777 2 1192.577543 597.2985 Unhealthy ribosome biogenesis protein 2 homolog OS=Homo sapiens OX=9606 GN=URB2 PE=1 SV=2 6 1439 - 283334 - - - -4.0878 - 1.545 0.142 - 268.9 1 2 0 -0.0049 10 0 0 0 3.35E+06 5.79E+06 - - - 1.3026 0.9998 221125_WJC_METTL3_EV_vs_WT_F07.04784.04784.2 0.000225 16-Nov K.QENESGYER[166.11].R "sp|Q9BUJ2|HNRL1_HUMAN,tr|M0R0K8|M0R0K8_HUMAN,tr|M0QYZ0|M0QYZ0_HUMAN,tr|A0A0A0MRA5|A0A0A0MRA5_HUMAN,tr|M0QZV6|M0QZV6_HUMAN,tr|B7Z4B8|B7Z4B8_HUMAN,tr|M0R203|M0R203_HUMAN" 7 1120.4661 1.66 93880 4784 2 1120.46463 561.2403 Heterogeneous nuclear ribonucleoprotein U-like protein 1 OS=Homo sapiens OX=9606 GN=HNRNPUL1 PE=1 SV=2 4.25 1439.8 - 1.62E+06 - - - -1.2682 - 2.199 0.464 - 675.4 1 2 0 -0.0014 9 0 0 0 2.12E+08 1.27E+08 - - - 4.7474 0.9935 221125_WJC_METTL3_EV_vs_WT_F07.04785.04785.2 1.01 14-Jul R.QSAC[160.03]NLEK[136.11].K sp|P35579|MYH9_HUMAN 1 956.4477 2.12 93881 4785 2 956.447142 479.2311 Myosin-9 OS=Homo sapiens OX=9606 GN=MYH9 PE=1 SV=4 5.99 1439.9 - 935812 - - - -0.5635 - 1.145 0.202 - 190.6 1 2 0 -0.0005 8 0 0 0 2.70E+07 1.27E+07 - - - 0.9412 0.9997 221125_WJC_METTL3_EV_vs_WT_F07.04787.04787.2 0.000697 20-Oct R.EEAAVDAQQQK.R sp|Q15149|PLEC_HUMAN 1 1215.5731 1.79 93883 4787 2 1215.571682 608.7938 Plectin OS=Homo sapiens OX=9606 GN=PLEC PE=1 SV=3 4.14 1440.1 - 634627 - - - -1.2035 - 2.044 0.397 - 383.7 1 2 0 -0.0015 11 0 0 0 7.14E+06 3.99E+06 - - - 3.9068 0.9995 221125_WJC_METTL3_EV_vs_WT_F07.04794.04794.2 0.281 14-Oct R.REEEELAR.R "sp|Q6Y7W6|GGYF2_HUMAN,tr|A0A7I2V3H7|A0A7I2V3H7_HUMAN,tr|I1E4Y6|I1E4Y6_HUMAN,tr|A0A7I2V516|A0A7I2V516_HUMAN,tr|A0A7I2V3H0|A0A7I2V3H0_HUMAN,tr|A0A7I2V361|A0A7I2V361_HUMAN,tr|E7ESB6|E7ESB6_HUMAN" 7 1030.5043 1.93 93888 4794 2 1030.503397 516.2594 GRB10-interacting GYF protein 2 OS=Homo sapiens OX=9606 GN=GIGYF2 PE=1 SV=1 4.49 1440.7 - 2.59E+06 - - - -0.9122 - 1.931 0.297 - 192.4 1 2 0 -0.0009 8 0 0 0 3.00E+07 1.55E+07 - - - 3.219 0.9999 221125_WJC_METTL3_EV_vs_WT_F07.04795.04795.2 5.19E-05 18-Dec R.SGSGNFGGGR.G "sp|P09651|ROA1_HUMAN,tr|A0A7I2YQX9|A0A7I2YQX9_HUMAN,tr|A0A7I2V661|A0A7I2V661_HUMAN,tr|A0A7I2V3K5|A0A7I2V3K5_HUMAN,tr|A0A7I2V4P7|A0A7I2V4P7_HUMAN,tr|F8VZ49|F8VZ49_HUMAN,tr|A0A7I2V3R8|A0A7I2V3R8_HUMAN,tr|F8W6I7|F8W6I7_HUMAN,tr|H0YH80|H0YH80_HUMAN,tr|A0A7I2V2L6|A0A7I2V2L6_HUMAN,tr|A0A7I2V3W0|A0A7I2V3W0_HUMAN,tr|A0A7I2V2R4|A0A7I2V2R4_HUMAN,tr|A0A2R8Y4L2|A0A2R8Y4L2_HUMAN,tr|A0A7I2V5L7|A0A7I2V5L7_HUMAN,tr|A0A7I2V453|A0A7I2V453_HUMAN" 15 894.3944 1.6 93889 4795 2 894.393265 448.2045 Heterogeneous nuclear ribonucleoprotein A1 OS=Homo sapiens OX=9606 GN=HNRNPA1 PE=1 SV=5 9.47 1440.8 - 1.80E+06 - - - -1.2612 - 2.484 0.504 - 636.9 1 2 0 -0.0011 10 0 0 0 1.10E+08 6.87E+07 - - - 5.3029 0.9995 221125_WJC_METTL3_EV_vs_WT_F07.04800.04800.2 0.00158 20-Sep R.EEAAVDAQQQK[136.11].R sp|Q15149|PLEC_HUMAN 1 1223.5873 1.79 93894 4800 2 1223.58644 612.8009 Plectin OS=Homo sapiens OX=9606 GN=PLEC PE=1 SV=3 4.14 1441.4 - 323698 - - - -0.7396 - 1.797 0.327 - 267.5 1 2 0 -0.0009 11 0 0 0 7.14E+06 3.99E+06 - - - 3.0415 0.9996 221125_WJC_METTL3_EV_vs_WT_F07.04807.04807.2 0.00354 20-Aug K.VPSGQNADVQK[136.11].T "sp|Q9GZZ1|NAA50_HUMAN,tr|A0A087WWJ2|A0A087WWJ2_HUMAN,tr|A0A0D9SF32|A0A0D9SF32_HUMAN,tr|C9J5J3|C9J5J3_HUMAN,tr|B0AZT5|B0AZT5_HUMAN,tr|E7EQ69|E7EQ69_HUMAN,tr|C9J5D1|C9J5D1_HUMAN" 7 1149.587 0.42 93899 4807 2 1149.585212 575.8008 N-alpha-acetyltransferase 50 OS=Homo sapiens OX=9606 GN=NAA50 PE=1 SV=1 5.81 1442.1 - 1.24E+06 - - - -1.5127 - 1.828 0.401 - 206 1 2 0 -0.0017 11 0 0 0 1.09E+07 2.59E+07 - - - 3.6341 0.9999 221125_WJC_METTL3_EV_vs_WT_F07.04809.04809.2 0.000829 20-Nov R.MATC[160.03]SSDQSVK[136.11].V "sp|Q96EE3|SEH1_HUMAN,tr|K7EPZ5|K7EPZ5_HUMAN,tr|K7EP88|K7EP88_HUMAN,tr|K7ENI5|K7ENI5_HUMAN,tr|K7ELV2|K7ELV2_HUMAN" 5 1220.5257 1.32 93901 4809 2 1220.525325 611.2701 Nucleoporin SEH1 OS=Homo sapiens OX=9606 GN=SEH1L PE=1 SV=3 5.59 1442.3 - 404872 - - - -0.2851 - 2.304 0.461 - 291.6 1 2 0 -0.0003 11 0 0 0 7.59E+06 5.75E+06 - - - 4.7038 0.9998 221125_WJC_METTL3_EV_vs_WT_F07.04814.04814.2 0.000308 16-Oct K.KGQASLYGK.R sp|Q92922|SMRC1_HUMAN 1 950.5185 6.5 93904 4814 2 950.517712 476.2665 SWI\SNF complex subunit SMARCC1 OS=Homo sapiens OX=9606 GN=SMARCC1 PE=1 SV=3 9.7 1442.9 - 9.21E+06 - - - -0.8616 - 2.002 0.48 - 346.4 1 2 0 -0.0008 9 0 0 0 2.72E+08 4.18E+07 - - - 4.5942 0.9998 221125_WJC_METTL3_EV_vs_WT_F07.04816.04816.2 0.0155 13/16 K.HIVENAVQK[136.11].E "sp|O00410|IPO5_HUMAN,tr|H0Y8C6|H0Y8C6_HUMAN" 2 1044.5807 0.9 93906 4816 2 1044.580426 523.2976 Importin-5 OS=Homo sapiens OX=9606 GN=IPO5 PE=1 SV=4 6.75 1443 - 2.41E+06 - - - -0.3035 - 2.41 0.389 - 601.3 1 2 0 -0.0003 9 0 0 0 8.97E+07 1.00E+08 - - - 4.4589 0.9999 221125_WJC_METTL3_EV_vs_WT_F07.04817.04817.2 0.15 14/16 K.HIVENAVQK.E "sp|O00410|IPO5_HUMAN,tr|H0Y8C6|H0Y8C6_HUMAN" 2 1036.5665 0.9 93907 4817 2 1036.566261 519.2905 Importin-5 OS=Homo sapiens OX=9606 GN=IPO5 PE=1 SV=4 6.75 1443.1 - 1.86E+06 - - - -0.2721 - 2.347 0.422 - 753.1 1 2 0 -0.0003 9 0 0 0 8.95E+07 9.99E+07 - - - 4.626 0.9999 221125_WJC_METTL3_EV_vs_WT_F07.04823.04823.2 2.44E-06 14-Nov R.NHAAPFSK[136.11].V "sp|Q92598|HS105_HUMAN,sp|P34932|HSP74_HUMAN,tr|A0A087WTS8|A0A087WTS8_HUMAN,tr|A0A0A0MSM0|A0A0A0MSM0_HUMAN,tr|A0A087WYC1|A0A087WYC1_HUMAN" 5 878.449 0.12 93911 4823 2 878.448675 440.2318 Heat shock protein 105 kDa OS=Homo sapiens OX=9606 GN=HSPH1 PE=1 SV=1 8.76 1443.8 - 6.68E+06 - - - -0.3711 - 2.258 0.557 - 752.4 1 2 0 -0.0003 8 0 0 0 1.39E+08 1.14E+09 - - - 5.6113 0.9951 221125_WJC_METTL3_EV_vs_WT_F07.04827.04827.2 0.0127 22-Sep R.DGGAASPATEGR[166.11].G "sp|Q7Z460|CLAP1_HUMAN,tr|F8WA11|F8WA11_HUMAN,tr|H0Y5T1|H0Y5T1_HUMAN" 3 1097.4977 0.27 93915 4827 2 1097.498735 549.7561 CLIP-associating protein 1 OS=Homo sapiens OX=9606 GN=CLASP1 PE=1 SV=1 4.37 1444.2 - 660906 - - - 0.9567 - 1.406 0.185 - 112.1 1 2 0 0.001 12 0 0 0 3.59E+06 1.35E+07 - - - 1.3036 1 221125_WJC_METTL3_EV_vs_WT_F07.04834.04834.3 3.85E-05 14/40 R.VATVADTDDHR.V sp|Q96JM7|LMBL3_HUMAN 1 1198.5578 1.26 93920 4834 3 1198.558112 400.5266 Lethal(3)malignant brain tumor-like protein 3 OS=Homo sapiens OX=9606 GN=L3MBTL3 PE=1 SV=2 4.41 1444.9 - 2.25E+06 - - - 0.2361 - 2.228 0.536 - 276.1 1 2 0 0.0003 11 0 0 0 4.07E+07 3.24E+07 - - - 6.7916 0.9995 221125_WJC_METTL3_EV_vs_WT_F07.04835.04835.3 0.00153 Nov-40 K.AVATYHANTER[166.11].E "sp|P51532|SMCA4_HUMAN,tr|A0A2R8Y7S2|A0A2R8Y7S2_HUMAN,tr|A0A2R8Y7F3|A0A2R8Y7F3_HUMAN,tr|A0A2R8YGG3|A0A2R8YGG3_HUMAN,tr|Q9HBD4|Q9HBD4_HUMAN,tr|A0A2R8Y440|A0A2R8Y440_HUMAN,tr|A0A2R8YG32|A0A2R8YG32_HUMAN,tr|A0A2R8YGP5|A0A2R8YGP5_HUMAN,tr|A0A2R8Y4P4|A0A2R8Y4P4_HUMAN,tr|A0A2R8Y4C5|A0A2R8Y4C5_HUMAN" 10 1241.6028 0.93 93921 4835 3 1241.600699 414.8749 Transcription activator BRG1 OS=Homo sapiens OX=9606 GN=SMARCA4 PE=1 SV=2 6.79 1445 - 1.48E+06 - - - -1.7075 - 2.137 0.306 - 154.4 1 2 0 -0.0021 11 0 0 0 6.09E+07 6.57E+07 - - - 4.1083 0.9615 221125_WJC_METTL3_EV_vs_WT_F07.04839.04839.2 0.0533 14-Aug K.FK[136.11]DPNAPK[136.11].R "sp|B2RPK0|HGB1A_HUMAN,sp|P09429|HMGB1_HUMAN,sp|P23497|SP100_HUMAN,tr|Q5T7C4|Q5T7C4_HUMAN" 4 931.5098 0.27 93925 4839 2 931.506819 466.7622 Putative high mobility group protein B1-like 1 OS=Homo sapiens OX=9606 GN=HMGB1P1 PE=5 SV=1 8.59 1445.5 - 617726 - - - -3.2184 - 1.815 0.255 - 198.3 1 2 1 -0.003 8 0 0 0 1.13E+08 4.10E+08 - - - 2.7213 0.9354 221125_WJC_METTL3_EV_vs_WT_F07.04842.04842.3 0.0276 Aug-32 R.FQESEER[166.11]PK[136.11].L sp|P34932|HSP74_HUMAN 1 1166.5687 0.12 93926 4842 3 1166.566343 389.8635 Heat shock 70 kDa protein 4 OS=Homo sapiens OX=9606 GN=HSPA4 PE=1 SV=4 4.79 1445.9 - 1.10E+07 - - - -1.9965 - 1.451 0.123 - 64.1 1 2 0 -0.0023 9 0 0 0 2.30E+07 1.97E+08 - - - 1.0326 0.9997 221125_WJC_METTL3_EV_vs_WT_F07.04844.04844.2 0.00413 14-Aug R.NHAAPFSK.V "sp|Q92598|HS105_HUMAN,sp|P34932|HSP74_HUMAN,tr|A0A087WTS8|A0A087WTS8_HUMAN,tr|A0A0A0MSM0|A0A0A0MSM0_HUMAN,tr|A0A087WYC1|A0A087WYC1_HUMAN" 5 870.4348 0.12 93928 4844 2 870.433802 436.2247 Heat shock protein 105 kDa OS=Homo sapiens OX=9606 GN=HSPH1 PE=1 SV=1 8.76 1446 - 4.08E+06 - - - -1.1477 - 1.582 0.497 - 277.5 1 2 0 -0.001 8 0 0 0 1.39E+08 1.14E+09 - - - 4.0949 0.9572 221125_WJC_METTL3_EV_vs_WT_F07.04845.04845.2 0.00705 12-May A.PGFGDNR.K "sp|P10809|CH60_HUMAN,tr|A0A7I2V2X6|A0A7I2V2X6_HUMAN,tr|A0A7I2YQK6|A0A7I2YQK6_HUMAN,tr|A0A7I2V599|A0A7I2V599_HUMAN,tr|A0A7I2V5M1|A0A7I2V5M1_HUMAN" 5 761.3457 1.99 93929 4845 2 761.344158 381.6801 "60 kDa heat shock protein, mitochondrial OS=Homo sapiens OX=9606 GN=HSPD1 PE=1 SV=2" 6.27 1446 - 2.83E+06 - - - -1.9623 - 1.249 0.493 - 75.2 1 1 0 -0.0015 7 0 0 0 6.66E+07 3.35E+07 - - - 3.3863 0.9997 221125_WJC_METTL3_EV_vs_WT_F07.04846.04846.2 0.000147 16-Sep K.TSPENVQDR[166.11].F sp|P49792|RBP2_HUMAN 1 1054.4919 1.14 93930 4846 2 1054.490396 528.2532 E3 SUMO-protein ligase RanBP2 OS=Homo sapiens OX=9606 GN=RANBP2 PE=1 SV=2 4.37 1446.1 - 2.79E+06 - - - -1.3997 - 1.92 0.437 - 501.4 1 2 0 -0.0015 9 0 0 0 4.80E+07 4.21E+07 - - - 4.1554 0.9998 221125_WJC_METTL3_EV_vs_WT_F07.04847.04847.3 0.000155 Dec-40 K.AVATYHANTER.E "sp|P51532|SMCA4_HUMAN,tr|A0A2R8Y7S2|A0A2R8Y7S2_HUMAN,tr|A0A2R8Y7F3|A0A2R8Y7F3_HUMAN,tr|A0A2R8YGG3|A0A2R8YGG3_HUMAN,tr|Q9HBD4|Q9HBD4_HUMAN,tr|A0A2R8Y440|A0A2R8Y440_HUMAN,tr|A0A2R8YG32|A0A2R8YG32_HUMAN,tr|A0A2R8YGP5|A0A2R8YGP5_HUMAN,tr|A0A2R8Y4P4|A0A2R8Y4P4_HUMAN,tr|A0A2R8Y4C5|A0A2R8Y4C5_HUMAN" 10 1231.5945 0.92 93931 4847 3 1231.591685 411.5388 Transcription activator BRG1 OS=Homo sapiens OX=9606 GN=SMARCA4 PE=1 SV=2 6.79 1446.1 - 2.37E+06 - - - -2.3254 - 2.047 0.422 - 157.8 1 2 0 -0.0029 11 0 0 0 6.01E+07 6.56E+07 - - - 5.2792 0.9992 221125_WJC_METTL3_EV_vs_WT_F07.04848.04848.2 6.26E-05 16-Nov R.FQESEER[166.11]PK[136.11].L sp|P34932|HSP74_HUMAN 1 1166.5687 0.03 93932 4848 2 1166.566538 584.2916 Heat shock 70 kDa protein 4 OS=Homo sapiens OX=9606 GN=HSPA4 PE=1 SV=4 4.79 1446.3 - 1.77E+06 - - - -1.8293 - 1.904 0.305 - 342.2 1 2 0 -0.0021 9 0 0 0 1.00E+06 3.47E+07 - - - 3.1561 0.9987 221125_WJC_METTL3_EV_vs_WT_F07.04853.04853.2 0.00332 16-Aug R.QIQEEEDEK.Q "sp|O43805|SSNA1_HUMAN,tr|A0A087WV26|A0A087WV26_HUMAN" 2 1146.5041 2.14 93935 4853 2 1146.502499 574.2593 Sjoegren syndrome nuclear autoantigen 1 OS=Homo sapiens OX=9606 GN=SSNA1 PE=1 SV=2 3.91 1446.9 - 1.39E+06 - - - -1.3633 - 1.657 0.262 - 301.6 1 2 0 -0.0016 9 0 0 0 2.51E+07 1.17E+07 - - - 2.4367 0.9996 221125_WJC_METTL3_EV_vs_WT_F07.04855.04855.2 2.20E-06 16-Nov R.YEEEEEQSR.S sp|Q9Y5B9|SP16H_HUMAN 1 1197.4786 0.91 93936 4855 2 1197.47837 599.7466 FACT complex subunit SPT16 OS=Homo sapiens OX=9606 GN=SUPT16H PE=1 SV=1 3.98 1447.1 - 2.26E+06 - - - -0.172 - 1.843 0.318 - 413.2 1 2 0 -0.0002 9 0 0 0 4.80E+07 5.28E+07 - - - 3.1585 0.9987 221125_WJC_METTL3_EV_vs_WT_F07.04857.04857.2 0.157 16-Oct R.YTR[166.11]PTPVQK[136.11].H "sp|O00571|DDX3X_HUMAN,sp|O15523|DDX3Y_HUMAN,tr|A0A2R8YFR4|A0A2R8YFR4_HUMAN,tr|A0A2R8YCW1|A0A2R8YCW1_HUMAN,tr|A0A2R8YDH3|A0A2R8YDH3_HUMAN,tr|A0A2R8YDT5|A0A2R8YDT5_HUMAN,tr|A0A2R8Y645|A0A2R8Y645_HUMAN,tr|A0A2R8YF78|A0A2R8YF78_HUMAN,tr|C9J8G5|C9J8G5_HUMAN,tr|A0A2R8Y4D2|A0A2R8Y4D2_HUMAN,tr|A0A0D9SFB3|A0A0D9SFB3_HUMAN,tr|A0A2R8YFS5|A0A2R8YFS5_HUMAN,tr|A0A0D9SF53|A0A0D9SF53_HUMAN,tr|C9J081|C9J081_HUMAN,tr|A0A2R8Y5G6|A0A2R8Y5G6_HUMAN,tr|A0A2R8Y7T2|A0A2R8Y7T2_HUMAN,tr|A0A0D9SG12|A0A0D9SG12_HUMAN,tr|F6S8Q4|F6S8Q4_HUMAN,tr|A0A2U3TZJ9|A0A2U3TZJ9_HUMAN,tr|A0A2R8Y4A4|A0A2R8Y4A4_HUMAN" 20 1106.6203 1.25 93938 4857 2 1106.619066 554.3174 ATP-dependent RNA helicase DDX3X OS=Homo sapiens OX=9606 GN=DDX3X PE=1 SV=3 9.99 1447.3 - 3.89E+06 - - - -1.1278 - 1.683 0.24 - 426.3 1 2 0 -0.0012 9 0 0 0 2.02E+08 1.61E+08 - - - 2.3193 0.9996 221125_WJC_METTL3_EV_vs_WT_F07.04859.04859.2 0.00232 20-Nov K.AVATYHANTER[166.11].E "sp|P51532|SMCA4_HUMAN,tr|A0A2R8Y7S2|A0A2R8Y7S2_HUMAN,tr|A0A2R8Y7F3|A0A2R8Y7F3_HUMAN,tr|A0A2R8YGG3|A0A2R8YGG3_HUMAN,tr|Q9HBD4|Q9HBD4_HUMAN,tr|A0A2R8Y440|A0A2R8Y440_HUMAN,tr|A0A2R8YG32|A0A2R8YG32_HUMAN,tr|A0A2R8YGP5|A0A2R8YGP5_HUMAN,tr|A0A2R8Y4P4|A0A2R8Y4P4_HUMAN,tr|A0A2R8Y4C5|A0A2R8Y4C5_HUMAN" 10 1241.6028 0.83 93940 4859 2 1241.60063 621.8087 Transcription activator BRG1 OS=Homo sapiens OX=9606 GN=SMARCA4 PE=1 SV=2 6.79 1447.6 - 561627 - - - -1.763 - 2.203 0.393 - 488.3 1 2 0 -0.0022 11 0 0 0 8.82E+06 1.06E+07 - - - 4.0797 0.9997 221125_WJC_METTL3_EV_vs_WT_F07.04864.04864.2 5.96E-07 16-Sep R.YEEEEEQSR[166.11].S sp|Q9Y5B9|SP16H_HUMAN 1 1207.4868 0.91 93942 4864 2 1207.485745 604.7507 FACT complex subunit SPT16 OS=Homo sapiens OX=9606 GN=SUPT16H PE=1 SV=1 3.98 1448.2 - 3.06E+06 - - - -0.9118 - 1.896 0.379 - 257.3 1 2 0 -0.0011 9 0 0 0 4.80E+07 5.28E+07 - - - 3.6908 0.8087 221125_WJC_METTL3_EV_vs_WT_F07.04865.04865.2 0.228 14-Jun A.PGFGDNR[166.11]K.N "sp|P10809|CH60_HUMAN,tr|A0A7I2V2X6|A0A7I2V2X6_HUMAN,tr|A0A7I2YQK6|A0A7I2YQK6_HUMAN,tr|A0A7I2V599|A0A7I2V599_HUMAN,tr|A0A7I2V5M1|A0A7I2V5M1_HUMAN" 5 899.4489 - 93943 4865 2 899.44991 450.7317 "60 kDa heat shock protein, mitochondrial OS=Homo sapiens OX=9606 GN=HSPD1 PE=1 SV=2" 9.18 1448.2 - 1.81E+06 - - - 1.1396 - 1.281 0.237 - 71.8 1 1 0 0.001 8 0 0 0 - - - - - 1.538 0.9998 221125_WJC_METTL3_EV_vs_WT_F07.04870.04870.2 5.90E-06 20-Sep K.ESTTVTC[160.03]TGEK[136.11].A "sp|Q92576|PHF3_HUMAN,tr|E9PE34|E9PE34_HUMAN,tr|E7ER40|E7ER40_HUMAN,tr|E7EVH3|E7EVH3_HUMAN" 4 1219.5482 0.67 93946 4870 2 1219.54695 610.7814 PHD finger protein 3 OS=Homo sapiens OX=9606 GN=PHF3 PE=1 SV=3 4.53 1448.8 - 987726 - - - -1.011 - 1.747 0.56 - 259.3 1 2 0 -0.0012 11 0 0 0 5.83E+06 8.73E+06 - - - 4.686 0.9998 221125_WJC_METTL3_EV_vs_WT_F07.04871.04871.2 1.05E-05 18-Nov R.TPDTPNNDPR[166.11].C "sp|Q16513|PKN2_HUMAN,tr|B1AL79|B1AL79_HUMAN" 2 1135.5133 2.08 93947 4871 2 1135.514047 568.7639 Serine\threonine-protein kinase N2 OS=Homo sapiens OX=9606 GN=PKN2 PE=1 SV=1 4.21 1448.9 - 1.40E+06 - - - 0.627 - 2.273 0.428 - 296.8 1 2 0 0.0007 10 0 0 0 1.19E+08 5.73E+07 - - - 4.4939 0.999 221125_WJC_METTL3_EV_vs_WT_F07.04875.04875.2 0.00255 12-Sep K.HDVNLGR[166.11].A sp|Q6P2Q9|PRP8_HUMAN 1 819.4227 1.7 93949 4875 2 819.421016 410.7186 Pre-mRNA-processing-splicing factor 8 OS=Homo sapiens OX=9606 GN=PRPF8 PE=1 SV=2 6.74 1449.5 - 1.56E+07 - - - -2.0185 - 1.551 0.37 - 229.1 1 2 0 -0.0017 7 0 0 0 3.31E+08 1.95E+08 - - - 3.164 0.9536 221125_WJC_METTL3_EV_vs_WT_F07.04876.04876.2 1.86 16-Sep R.YTRPTPVQK.H "sp|O00571|DDX3X_HUMAN,sp|O15523|DDX3Y_HUMAN,tr|A0A2R8YFR4|A0A2R8YFR4_HUMAN,tr|A0A2R8YCW1|A0A2R8YCW1_HUMAN,tr|A0A2R8YDH3|A0A2R8YDH3_HUMAN,tr|A0A2R8YDT5|A0A2R8YDT5_HUMAN,tr|A0A2R8Y645|A0A2R8Y645_HUMAN,tr|A0A2R8YF78|A0A2R8YF78_HUMAN,tr|C9J8G5|C9J8G5_HUMAN,tr|A0A2R8Y4D2|A0A2R8Y4D2_HUMAN,tr|A0A0D9SFB3|A0A0D9SFB3_HUMAN,tr|A0A2R8YFS5|A0A2R8YFS5_HUMAN,tr|A0A0D9SF53|A0A0D9SF53_HUMAN,tr|C9J081|C9J081_HUMAN,tr|A0A2R8Y5G6|A0A2R8Y5G6_HUMAN,tr|A0A2R8Y7T2|A0A2R8Y7T2_HUMAN,tr|A0A0D9SG12|A0A0D9SG12_HUMAN,tr|F6S8Q4|F6S8Q4_HUMAN,tr|A0A2U3TZJ9|A0A2U3TZJ9_HUMAN,tr|A0A2R8Y4A4|A0A2R8Y4A4_HUMAN" 20 1088.5978 1.26 93950 4876 2 1088.595918 545.3062 ATP-dependent RNA helicase DDX3X OS=Homo sapiens OX=9606 GN=DDX3X PE=1 SV=3 9.99 1449.5 - 7.33E+06 - - - -1.7692 - 1.275 0.034 - 238.6 1 2 0 -0.0019 9 0 0 0 2.02E+08 1.61E+08 - - - -0.0056 0.975 221125_WJC_METTL3_EV_vs_WT_F07.04877.04877.2 0.00791 14-Jul R.EK[136.11]DQADFR[166.11].G sp|Q96I24|FUBP3_HUMAN 1 1025.4897 1.44 93951 4877 2 1025.487018 513.7521 Far upstream element-binding protein 3 OS=Homo sapiens OX=9606 GN=FUBP3 PE=1 SV=2 4.56 1449.6 - 5.00E+06 - - - -2.6085 - 1.574 0.313 - 201.7 1 2 1 -0.0027 8 0 0 0 2.88E+08 1.99E+08 - - - 2.7201 0.9998 221125_WJC_METTL3_EV_vs_WT_F07.04878.04878.2 0.0192 22-Oct R.SAGGEPGPEAGR.A "sp|O95785|WIZ_HUMAN,tr|A0A669KBG4|A0A669KBG4_HUMAN,tr|A0A2R8YFV2|A0A2R8YFV2_HUMAN,tr|A0A669KAV7|A0A669KAV7_HUMAN,tr|M0QXA7|M0QXA7_HUMAN,tr|A0A669KBH9|A0A669KBH9_HUMAN,tr|B9EGQ5|B9EGQ5_HUMAN" 7 1083.4945 1.63 93952 4878 2 1083.494366 542.7545 Protein Wiz OS=Homo sapiens OX=9606 GN=WIZ PE=1 SV=2 4.53 1449.7 - 1.15E+06 - - - -0.1246 - 2.112 0.451 - 245.4 1 2 0 -0.0001 12 0 0 0 5.08E+07 3.11E+07 - - - 4.3392 1 221125_WJC_METTL3_EV_vs_WT_F07.04879.04879.2 1.17E-08 16-Nov K.C[160.03]C[160.03]NTC[160.03]EDVR[166.11].E "sp|Q9Y282|ERGI3_HUMAN,tr|H0Y621|H0Y621_HUMAN,tr|H0Y5K5|H0Y5K5_HUMAN,tr|A0A1W2PPS8|A0A1W2PPS8_HUMAN" 4 1222.4404 1.2 93953 4879 2 1222.440358 612.2275 Endoplasmic reticulum-Golgi intermediate compartment protein 3 OS=Homo sapiens OX=9606 GN=ERGIC3 PE=1 SV=1 4.37 1449.8 - 996912 - - - -0.0728 - 2.295 0.715 - 495.5 1 2 0 -0.0001 9 0 0 0 1.87E+07 1.56E+07 - - - 6.7253 0.9997 221125_WJC_METTL3_EV_vs_WT_F07.04880.04880.2 0.00139 12-Sep R.HTLAYDK.G "sp|Q6P2Q9|PRP8_HUMAN,tr|I3L3Z8|I3L3Z8_HUMAN" 2 846.4236 0.02 93954 4880 2 846.423829 424.2191 Pre-mRNA-processing-splicing factor 8 OS=Homo sapiens OX=9606 GN=PRPF8 PE=1 SV=2 6.74 1449.9 - 859166 - - - 0.3084 - 1.765 0.37 - 282.7 1 2 0 0.0003 7 0 0 0 1.24E+07 5.48E+08 - - - 3.574 0.9998 221125_WJC_METTL3_EV_vs_WT_F07.04881.04881.2 0.00017 22-Oct R.SAGGEPGPEAGR[166.11].A "sp|O95785|WIZ_HUMAN,tr|A0A669KBG4|A0A669KBG4_HUMAN,tr|A0A2R8YFV2|A0A2R8YFV2_HUMAN,tr|A0A669KAV7|A0A669KAV7_HUMAN,tr|M0QXA7|M0QXA7_HUMAN,tr|A0A669KBH9|A0A669KBH9_HUMAN,tr|B9EGQ5|B9EGQ5_HUMAN" 7 1093.5028 4.3 93955 4881 2 1093.502004 547.7587 Protein Wiz OS=Homo sapiens OX=9606 GN=WIZ PE=1 SV=2 4.53 1450.1 - 737950 - - - -0.7014 - 2.097 0.431 - 285.2 1 2 0 -0.0008 12 0 0 0 1.47E+08 3.43E+07 - - - 4.1725 0.9999 221125_WJC_METTL3_EV_vs_WT_F07.04882.04882.2 3.19E-05 22-Dec K.VPAQANGTPTTK[136.11].S "sp|Q9BQG0|MBB1A_HUMAN,tr|I3L1L3|I3L1L3_HUMAN" 2 1191.6339 0.83 93956 4882 2 1191.63364 596.8242 Myb-binding protein 1A OS=Homo sapiens OX=9606 GN=MYBBP1A PE=1 SV=2 8.72 1450.2 - 692644 - - - -0.219 - 2.373 0.493 - 555 1 2 0 -0.0003 12 0 0 0 1.31E+07 1.57E+07 - - - 4.956 0.9997 221125_WJC_METTL3_EV_vs_WT_F07.04885.04885.2 0.000504 13/22 K.VPAQANGTPTTK.S "sp|Q9BQG0|MBB1A_HUMAN,tr|I3L1L3|I3L1L3_HUMAN" 2 1183.6197 0.83 93959 4885 2 1183.617082 592.8171 Myb-binding protein 1A OS=Homo sapiens OX=9606 GN=MYBBP1A PE=1 SV=2 8.72 1450.6 - 431563 - - - -2.2127 - 2.427 0.473 - 501.8 1 2 0 -0.0026 12 0 0 0 1.31E+07 1.57E+07 - - - 4.8667 0.8345 221125_WJC_METTL3_EV_vs_WT_F07.04888.04888.2 0.305 14-Jul K.FKDPNAPK.R "sp|B2RPK0|HGB1A_HUMAN,sp|P09429|HMGB1_HUMAN,sp|P23497|SP100_HUMAN,tr|Q5T7C4|Q5T7C4_HUMAN" 4 915.4814 0.28 93960 4888 2 915.479233 458.748 Putative high mobility group protein B1-like 1 OS=Homo sapiens OX=9606 GN=HMGB1P1 PE=5 SV=1 8.59 1451 - 2.71E+06 - - - -2.3856 - 1.315 0.147 - 127 1 2 1 -0.0022 8 0 0 0 1.13E+08 4.10E+08 - - - 0.9519 0.9203 221125_WJC_METTL3_EV_vs_WT_F07.04894.04894.2 0.00765 14-Aug N.NSNTTFQK[136.11].R "sp|Q9NYF8|BCLF1_HUMAN,tr|H0YF14|H0YF14_HUMAN" 2 946.46 1.92 93964 4894 2 946.458193 474.2373 Bcl-2-associated transcription factor 1 OS=Homo sapiens OX=9606 GN=BCLAF1 PE=1 SV=2 8.75 1451.6 - 3.62E+06 - - - -1.867 - 1.616 0.293 - 319.4 1 1 0 -0.0018 8 0 0 0 3.42E+08 1.78E+08 - - - 2.6521 0.9996 221125_WJC_METTL3_EV_vs_WT_F07.04895.04895.2 0.000283 22-Nov K.TSQVGAASAPAK[136.11].E "sp|Q13428|TCOF_HUMAN,tr|E7ETY2|E7ETY2_HUMAN,tr|H0Y8Y7|H0Y8Y7_HUMAN,tr|A0A3B3IS06|A0A3B3IS06_HUMAN,tr|A0A6I8PRA0|A0A6I8PRA0_HUMAN,tr|A0A2R8Y857|A0A2R8Y857_HUMAN" 6 1094.5811 1.27 93965 4895 2 1094.580057 548.2978 Treacle protein OS=Homo sapiens OX=9606 GN=TCOF1 PE=1 SV=3 8.41 1451.7 - 1.96E+06 - - - -0.9867 - 1.79 0.408 - 400 1 2 0 -0.0011 12 0 0 0 4.78E+07 3.78E+07 - - - 3.5861 0.9991 221125_WJC_METTL3_EV_vs_WT_F07.04896.04896.3 0.000562 Oct-40 K.LGDGVDKDEAK.A sp|Q96BR5|COA7_HUMAN 1 1145.5564 1.09 93966 4896 3 1145.553999 382.8594 Cytochrome c oxidase assembly factor 7 OS=Homo sapiens OX=9606 GN=COA7 PE=1 SV=2 4.23 1451.7 - 1.81E+06 - - - -2.1239 - 2.174 0.395 - 91.6 1 2 1 -0.0024 11 0 0 0 2.63E+07 2.42E+07 - - - 5.1493 0.9938 221125_WJC_METTL3_EV_vs_WT_F07.04898.04898.2 4.89E-05 20-Sep K.LGDGVDK[136.11]DEAK[136.11].A sp|Q96BR5|COA7_HUMAN 1 1161.5848 1.15 93968 4898 2 1161.584375 581.7997 Cytochrome c oxidase assembly factor 7 OS=Homo sapiens OX=9606 GN=COA7 PE=1 SV=2 4.23 1451.9 - 331602 - - - -0.3934 - 1.824 0.305 - 217.8 1 2 1 -0.0005 11 0 0 0 3.32E+06 2.89E+06 - - - 2.9195 0.999 221125_WJC_METTL3_EV_vs_WT_F07.04902.04902.3 0.000689 Sep-40 K.LGDGVDK[136.11]DEAK[136.11].A sp|Q96BR5|COA7_HUMAN 1 1161.5848 1.08 93970 4902 3 1161.584039 388.2022 Cytochrome c oxidase assembly factor 7 OS=Homo sapiens OX=9606 GN=COA7 PE=1 SV=2 4.23 1452.4 - 1.43E+06 - - - -0.6827 - 2.13 0.341 - 80.4 1 2 1 -0.0008 11 0 0 0 2.60E+07 2.41E+07 - - - 4.4896 0.9993 221125_WJC_METTL3_EV_vs_WT_F07.04916.04916.2 0.0045 18-Aug R.AEQLSQENEK[136.11].L "sp|Q5M775|CYTSB_HUMAN,tr|A0A7I2YQJ3|A0A7I2YQJ3_HUMAN,tr|A0A7I2V416|A0A7I2V416_HUMAN,tr|A0A7I2V486|A0A7I2V486_HUMAN,tr|A0A7P0TAS3|A0A7P0TAS3_HUMAN,tr|A0A7I2V451|A0A7I2V451_HUMAN,tr|A0A7P0T9K0|A0A7P0T9K0_HUMAN,tr|A0A7P0Z4I1|A0A7P0Z4I1_HUMAN,tr|A0A7I2V562|A0A7I2V562_HUMAN,tr|A0A7P0TB87|A0A7P0TB87_HUMAN,tr|A0A7P0TBP2|A0A7P0TBP2_HUMAN,tr|J3QS22|J3QS22_HUMAN" 12 1182.5608 1.52 93980 4916 2 1182.559133 592.2877 Cytospin-B OS=Homo sapiens OX=9606 GN=SPECC1 PE=1 SV=1 4.25 1454.2 - 425349 - - - -1.4063 - 1.659 0.356 - 237.9 1 2 0 -0.0017 10 0 0 0 8.30E+06 5.47E+06 - - - 3.0829 0.9899 221125_WJC_METTL3_EV_vs_WT_F07.04922.04922.2 1.57 12-Jun R.REPLPSR.R "sp|Q96E39|RMXL1_HUMAN,sp|P38159|RBMX_HUMAN,sp|Q8IZ40|RCOR2_HUMAN,tr|H3BUY5|H3BUY5_HUMAN,tr|H3BT71|H3BT71_HUMAN,tr|H0Y6E7|H0Y6E7_HUMAN" 6 853.477 1.51 93984 4922 2 853.476012 427.7458 "RNA binding motif protein, X-linked-like-1 OS=Homo sapiens OX=9606 GN=RBMXL1 PE=1 SV=1" 9.6 1454.8 - 2.33E+06 - - - -1.1576 - 1.408 0.089 - 89.5 1 2 0 -0.001 7 0 0 0 1.96E+08 1.30E+08 - - - 0.7822 0.9979 221125_WJC_METTL3_EV_vs_WT_F07.04932.04932.2 0.0239 16-Aug R.DLSENNDQR.Q sp|Q8NBJ4|GOLM1_HUMAN 1 1089.4687 1.61 93990 4932 2 1089.467718 545.7416 Golgi membrane protein 1 OS=Homo sapiens OX=9606 GN=GOLM1 PE=1 SV=1 4.03 1456.2 - 4.38E+06 - - - -0.883 - 1.215 0.307 - 197.4 1 2 0 -0.001 9 0 0 0 7.05E+07 4.39E+07 - - - 1.8716 0.9513 221125_WJC_METTL3_EV_vs_WT_F07.04934.04934.2 3.4 12-Jun R.R[166.11]EPLPSR[166.11].R "sp|Q96E39|RMXL1_HUMAN,sp|P38159|RBMX_HUMAN,sp|Q8IZ40|RCOR2_HUMAN,tr|H3BUY5|H3BUY5_HUMAN,tr|H3BT71|H3BT71_HUMAN,tr|H0Y6E7|H0Y6E7_HUMAN" 6 873.4935 1.5 93992 4934 2 873.493069 437.754 "RNA binding motif protein, X-linked-like-1 OS=Homo sapiens OX=9606 GN=RBMXL1 PE=1 SV=1" 9.6 1456.3 - 3.08E+06 - - - -0.5392 - 1.077 0.044 - 94.3 1 2 0 -0.0005 7 0 0 0 1.95E+08 1.29E+08 - - - -0.3991 0.8493 221125_WJC_METTL3_EV_vs_WT_F07.04935.04935.2 3.45 12-Apr K.KDMMDIK.Y sp|Q96RL7|VP13A_HUMAN 1 879.4194 0.77 93993 4935 2 879.421091 440.717 Vacuolar protein sorting-associated protein 13A OS=Homo sapiens OX=9606 GN=VPS13A PE=1 SV=2 5.96 1456.3 - 1.06E+06 - - - 1.9115 - 0.903 0.121 - 62.4 5 2 0 0.0017 7 0 0 0 1.98E+07 2.57E+07 - - - -0.7013 0.9998 221125_WJC_METTL3_EV_vs_WT_F07.04939.04939.2 6.78E-06 18-Jun R.IIEC[160.03]THC[160.03]GC[160.03]R.G "sp|P41223|BUD31_HUMAN,tr|C9JCD9|C9JCD9_HUMAN" 2 1304.5424 0.72 93997 4939 2 1304.543798 653.2785 Protein BUD31 homolog OS=Homo sapiens OX=9606 GN=BUD31 PE=1 SV=2 6.72 1456.8 - 205615 - - - 1.0739 - 1.522 0.639 - 71.3 1 2 0 0.0014 10 0 0 0 2.59E+06 3.58E+06 - - - 4.9326 0.8426 221125_WJC_METTL3_EV_vs_WT_F07.04944.04944.2 0.00928 12-Jun V.LSEGHQR.T sp|O76071|CIAO1_HUMAN 1 825.4093 1.04 94000 4944 2 825.407961 413.7119 Probable cytosolic iron-sulfur protein assembly protein CIAO1 OS=Homo sapiens OX=9606 GN=CIAO1 PE=1 SV=1 6.75 1457.3 - 775896 - - - -1.6392 - 1.462 0.219 - 120.1 1 1 0 -0.0014 7 0 0 0 1.32E+07 1.27E+07 - - - 1.8615 0.9995 221125_WJC_METTL3_EV_vs_WT_F07.04945.04945.2 0.000172 16-Oct R.QEQIDNQTR[166.11].L "sp|Q13813|SPTN1_HUMAN,tr|A0A0D9SGF6|A0A0D9SGF6_HUMAN" 2 1140.5399 0.32 94001 4945 2 1140.542319 571.2772 "Spectrin alpha chain, non-erythrocytic 1 OS=Homo sapiens OX=9606 GN=SPTAN1 PE=1 SV=3" 4.37 1457.4 - 564217 - - - 2.1341 - 1.835 0.452 - 607.9 1 2 0 0.0024 9 0 0 0 2.15E+07 6.82E+07 - - - 4.1349 0.9999 221125_WJC_METTL3_EV_vs_WT_F07.04947.04947.2 0.0001 18-Oct K.QASC[160.03]SGDEYR[166.11].S "sp|O95394|AGM1_HUMAN,tr|A0A494C1E2|A0A494C1E2_HUMAN,tr|A0A494C099|A0A494C099_HUMAN,tr|J3KN95|J3KN95_HUMAN,tr|D6RIS6|D6RIS6_HUMAN,tr|A0A494C0G1|A0A494C0G1_HUMAN,tr|A0A494C1Q4|A0A494C1Q4_HUMAN,tr|A0A494C163|A0A494C163_HUMAN,tr|H0Y987|H0Y987_HUMAN,tr|A0A087WT27|A0A087WT27_HUMAN" 10 1181.4647 0.34 94003 4947 2 1181.464146 591.7396 Phosphoacetylglucosamine mutase OS=Homo sapiens OX=9606 GN=PGM3 PE=1 SV=1 4.37 1457.7 - 247961 - - - -0.4444 - 2.02 0.546 - 539.4 1 2 0 -0.0005 10 0 0 0 5.11E+06 1.51E+07 - - - 5.0362 0.9981 221125_WJC_METTL3_EV_vs_WT_F07.04951.04951.2 0.256 12-Aug K.RYESQLR.D sp|O15212|PFD6_HUMAN 1 950.4934 2.11 94005 4951 2 950.494573 476.254 Prefoldin subunit 6 OS=Homo sapiens OX=9606 GN=PFDN6 PE=1 SV=1 8.75 1458.1 - 2.86E+06 - - - 1.2562 - 1.65 0.21 - 159.1 1 2 0 0.0012 7 0 0 0 5.95E+07 2.82E+07 - - - 2.1784 0.9263 221125_WJC_METTL3_EV_vs_WT_F07.04952.04952.2 13.9 12-Jul R.R[166.11]LDPPSR[166.11].F "sp|Q8IX12|CCAR1_HUMAN,tr|F5H2E6|F5H2E6_HUMAN,tr|F5H1H2|F5H1H2_HUMAN,tr|A0A0C4DGG8|A0A0C4DGG8_HUMAN,tr|F5H3E1|F5H3E1_HUMAN" 5 859.4779 4.75 94006 4952 2 859.477971 430.7462 Cell division cycle and apoptosis regulator protein 1 OS=Homo sapiens OX=9606 GN=CCAR1 PE=1 SV=2 9.6 1458.2 - 2.78E+06 - - - 0.0942 - 1.084 0.002 - 246.4 1 2 0 0.0001 7 0 0 0 4.96E+08 1.04E+08 - - - -0.6887 0.9997 221125_WJC_METTL3_EV_vs_WT_F07.04953.04953.2 0.000843 16-Oct R.QEQIDNQTR.L "sp|Q13813|SPTN1_HUMAN,tr|A0A0D9SGF6|A0A0D9SGF6_HUMAN" 2 1130.5316 0.24 94007 4953 2 1130.532951 566.2731 "Spectrin alpha chain, non-erythrocytic 1 OS=Homo sapiens OX=9606 GN=SPTAN1 PE=1 SV=3" 4.37 1458.3 - 1.09E+06 - - - 1.1817 - 1.87 0.431 - 529.3 1 2 0 0.0013 9 0 0 0 1.45E+07 6.01E+07 - - - 4.0348 0.9855 221125_WJC_METTL3_EV_vs_WT_F07.04954.04954.2 0.41 24-Jul K.AAAAPAGGNPEQR[166.11].L "sp|Q68DK7|MSL1_HUMAN,tr|J3KSZ8|J3KSZ8_HUMAN,tr|J3QQY0|J3QQY0_HUMAN" 3 1218.5981 0.1 94008 4954 2 1218.602299 610.3063 Male-specific lethal 1 homolog OS=Homo sapiens OX=9606 GN=MSL1 PE=1 SV=3 6.05 1458.4 - 1.07E+06 - - - 3.472 - 1.385 0.264 - 113.1 2 2 0 0.0042 13 0 0 0 3.53E+06 3.54E+07 - - - 1.691 1 221125_WJC_METTL3_EV_vs_WT_F07.04955.04955.2 1.77E-05 18-Nov K.QASC[160.03]SGDEYR.S "sp|O95394|AGM1_HUMAN,tr|A0A494C1E2|A0A494C1E2_HUMAN,tr|A0A494C099|A0A494C099_HUMAN,tr|J3KN95|J3KN95_HUMAN,tr|D6RIS6|D6RIS6_HUMAN,tr|A0A494C0G1|A0A494C0G1_HUMAN,tr|A0A494C1Q4|A0A494C1Q4_HUMAN,tr|A0A494C163|A0A494C163_HUMAN,tr|H0Y987|H0Y987_HUMAN,tr|A0A087WT27|A0A087WT27_HUMAN" 10 1171.4564 0.34 94009 4955 2 1171.456474 586.7355 Phosphoacetylglucosamine mutase OS=Homo sapiens OX=9606 GN=PGM3 PE=1 SV=1 4.37 1458.6 - 355493 - - - 0.0623 - 2.063 0.631 - 558.1 1 2 0 0.0001 10 0 0 0 5.11E+06 1.51E+07 - - - 5.7229 0.9996 221125_WJC_METTL3_EV_vs_WT_F07.04957.04957.2 7.06E-07 18-Jul R.IIEC[160.03]THC[160.03]GC[160.03]R[166.11].G "sp|P41223|BUD31_HUMAN,tr|C9JCD9|C9JCD9_HUMAN" 2 1314.5507 0.72 94011 4957 2 1314.547136 658.2826 Protein BUD31 homolog OS=Homo sapiens OX=9606 GN=BUD31 PE=1 SV=2 6.72 1458.8 - 112615 - - - -2.6861 - 1.498 0.67 - 144.9 1 2 0 -0.0035 10 0 0 0 2.59E+06 3.58E+06 - - - 5.1166 0.9997 221125_WJC_METTL3_EV_vs_WT_F07.04960.04960.2 0.00107 18-Sep R.GQENGLDGTK.S "sp|Q14157|UBP2L_HUMAN,tr|Q5VU78|Q5VU78_HUMAN,tr|F8W726|F8W726_HUMAN,tr|Q5VU81|Q5VU81_HUMAN,tr|Q5VU79|Q5VU79_HUMAN,tr|Q5VU80|Q5VU80_HUMAN,tr|Q5VU77|Q5VU77_HUMAN" 7 1017.4727 1.67 94012 4960 2 1017.472572 509.7436 Ubiquitin-associated protein 2-like OS=Homo sapiens OX=9606 GN=UBAP2L PE=1 SV=2 4.37 1459.2 - 4.33E+06 - - - -0.1288 - 1.981 0.38 - 398.8 1 2 0 -0.0001 10 0 0 0 2.22E+08 1.33E+08 - - - 3.7558 0.998 221125_WJC_METTL3_EV_vs_WT_F07.04961.04961.2 0.00697 16-Nov R.LKEAISTSK.E "sp|O95721|SNP29_HUMAN,tr|C9JAF7|C9JAF7_HUMAN" 2 975.5601 2.43 94013 4961 2 975.559341 488.7873 Synaptosomal-associated protein 29 OS=Homo sapiens OX=9606 GN=SNAP29 PE=1 SV=1 8.59 1459.3 - 1.84E+06 - - - -0.738 - 2.188 0.411 - 298.5 1 2 1 -0.0007 9 0 0 0 3.53E+07 1.45E+07 - - - 4.3416 0.9999 221125_WJC_METTL3_EV_vs_WT_F07.04962.04962.3 0.000548 Dec-36 R.VREMEEEAEK.L "sp|Q86U42|PABP2_HUMAN,tr|A0A7I2V383|A0A7I2V383_HUMAN" 2 1248.5656 0.07 94014 4962 3 1248.564983 417.1958 Polyadenylate-binding protein 2 OS=Homo sapiens OX=9606 GN=PABPN1 PE=1 SV=3 4.33 1459.4 - 2.27E+06 - - - -0.5078 - 2.536 0.478 - 296.5 1 2 1 -0.0006 10 0 0 0 6.10E+07 8.31E+08 - - - 6.5868 0.9992 221125_WJC_METTL3_EV_vs_WT_F07.04964.04964.2 0.00436 18-Aug K.EANLQQNEEK[136.11].N "sp|Q9NY27|PP4R2_HUMAN,tr|H7C559|H7C559_HUMAN,tr|C9IZ04|C9IZ04_HUMAN" 3 1209.5717 0.5 94016 4964 2 1209.570077 605.7931 Serine\threonine-protein phosphatase 4 regulatory subunit 2 OS=Homo sapiens OX=9606 GN=PPP4R2 PE=1 SV=3 4.25 1459.6 - 522178 - - - -1.3377 - 1.495 0.371 - 249.7 1 2 0 -0.0016 10 0 0 0 2.52E+06 5.02E+06 - - - 2.9032 0.967 221125_WJC_METTL3_EV_vs_WT_F07.04965.04965.2 0.122 18-Sep R.VR[166.11]EMEEEAEK[136.11].L "sp|Q86U42|PABP2_HUMAN,tr|A0A7I2V383|A0A7I2V383_HUMAN" 2 1266.5881 1.22 94017 4965 2 1266.587517 634.3013 Polyadenylate-binding protein 2 OS=Homo sapiens OX=9606 GN=PABPN1 PE=1 SV=3 4.33 1459.7 - 431176 - - - -0.45 - 1.816 0.105 - 267.9 1 2 1 -0.0006 10 0 0 0 1.18E+07 9.68E+06 - - - 1.4817 0.8962 221125_WJC_METTL3_EV_vs_WT_F07.04967.04967.2 1.04 14-Jul R.NK[136.11]FEEAER[166.11].S "sp|P14314|GLU2B_HUMAN,tr|K7ELL7|K7ELL7_HUMAN,tr|A0A0C4DGP4|A0A0C4DGP4_HUMAN" 3 1039.5053 1.12 94018 4967 2 1039.505072 520.7599 Glucosidase 2 subunit beta OS=Homo sapiens OX=9606 GN=PRKCSH PE=1 SV=2 4.79 1460 - 1.03E+06 - - - -0.2607 - 1.257 0.118 - 197.1 1 2 1 -0.0003 8 0 0 0 1.24E+07 1.11E+07 - - - 0.6023 0.9998 221125_WJC_METTL3_EV_vs_WT_F07.04969.04969.2 0.000113 14-Sep K.HEDSAIPR.R sp|Q99459|CDC5L_HUMAN 1 923.4461 1.42 94019 4969 2 923.446089 462.7303 Cell division cycle 5-like protein OS=Homo sapiens OX=9606 GN=CDC5L PE=1 SV=2 5.32 1460.2 - 3.36E+06 - - - -0.0054 - 1.775 0.464 - 227.2 1 2 0 0 8 0 0 0 1.22E+08 8.57E+07 - - - 4.1987 0.9967 221125_WJC_METTL3_EV_vs_WT_F07.04970.04970.2 0.000664 16-Nov K.MKEQEDLAK.V "sp|Q9NP61|ARFG3_HUMAN,tr|H0Y6A0|H0Y6A0_HUMAN" 2 1090.5329 1.66 94020 4970 2 1090.530948 546.2737 ADP-ribosylation factor GTPase-activating protein 3 OS=Homo sapiens OX=9606 GN=ARFGAP3 PE=1 SV=1 4.68 1460.2 - 2.55E+06 - - - -1.7533 - 1.937 0.466 - 313.6 1 2 1 -0.0019 9 0 0 0 4.54E+07 2.73E+07 - - - 4.395 0.9794 221125_WJC_METTL3_EV_vs_WT_F07.04973.04973.2 0.353 16-Jun K.YSSSQPEPR[166.11].T "sp|O14757|CHK1_HUMAN,tr|E7EPP6|E7EPP6_HUMAN" 2 1059.4861 2.8 94023 4973 2 1059.488216 530.7503 Serine\threonine-protein kinase Chk1 OS=Homo sapiens OX=9606 GN=CHEK1 PE=1 SV=2 6 1460.4 - 1.13E+06 - - - 2.0368 - 1.112 0.184 - 85.3 1 2 0 0.0022 9 0 0 0 3.79E+07 1.35E+07 - - - 0.7065 0.9998 221125_WJC_METTL3_EV_vs_WT_F07.04976.04976.2 2.84E-05 20-Nov K.AATGAC[160.03]MTC[160.03]NK.H "sp|P55197|AF10_HUMAN,tr|A0A494C0R2|A0A494C0R2_HUMAN,tr|A0A494C038|A0A494C038_HUMAN" 3 1183.4784 2.86 94026 4976 2 1183.476496 592.7465 Protein AF-10 OS=Homo sapiens OX=9606 GN=MLLT10 PE=1 SV=2 8.1 1460.7 - 648924 - - - -1.608 - 2.414 0.429 - 635 1 2 0 -0.0019 11 0 0 0 1.32E+07 4.61E+06 - - - 4.5931 0.9957 221125_WJC_METTL3_EV_vs_WT_F07.04979.04979.2 0.0117 18-Sep R.VREMEEEAEK.L "sp|Q86U42|PABP2_HUMAN,tr|A0A7I2V383|A0A7I2V383_HUMAN" 2 1248.5656 1.24 94029 4979 2 1248.566312 625.2901 Polyadenylate-binding protein 2 OS=Homo sapiens OX=9606 GN=PABPN1 PE=1 SV=3 4.33 1461.1 - 442012 - - - 0.5566 - 2.189 0.294 - 249.9 1 2 1 0.0007 10 0 0 0 1.20E+07 9.68E+06 - - - 3.3991 0.9999 221125_WJC_METTL3_EV_vs_WT_F07.04983.04983.3 2.60E-05 Dec-44 R.KTVGVEPAADGK.G "sp|P46779|RL28_HUMAN,tr|H0YMF4|H0YMF4_HUMAN,tr|H0YLP6|H0YLP6_HUMAN,tr|H0YKD8|H0YKD8_HUMAN" 4 1170.6245 1.23 94031 4983 3 1170.622342 391.2154 60S ribosomal protein L28 OS=Homo sapiens OX=9606 GN=RPL28 PE=1 SV=3 6.07 1461.5 - 1.43E+06 - - - -1.8025 - 2.652 0.373 - 249 1 2 0 -0.0021 12 0 0 0 3.15E+07 2.56E+07 - - - 5.4014 0.9987 221125_WJC_METTL3_EV_vs_WT_F07.04984.04984.2 0.00052 14-Sep K.HEDSAIPR[166.11].R sp|Q99459|CDC5L_HUMAN 1 933.4544 1.43 94032 4984 2 933.453241 467.7345 Cell division cycle 5-like protein OS=Homo sapiens OX=9606 GN=CDC5L PE=1 SV=2 5.32 1461.6 - 4.91E+06 - - - -1.2031 - 1.675 0.241 - 187 1 2 0 -0.0011 8 0 0 0 1.21E+08 8.52E+07 - - - 2.3763 0.9498 221125_WJC_METTL3_EV_vs_WT_F07.04989.04989.2 0.000539 14-Aug Y.GDGPRPPK.M sp|Q08211|DHX9_HUMAN 1 822.4348 0.57 94035 4989 2 822.433006 412.2247 ATP-dependent RNA helicase A OS=Homo sapiens OX=9606 GN=DHX9 PE=1 SV=4 8.75 1462.2 - 2.46E+06 - - - -2.1825 - 1.705 0.369 - 214.4 1 1 0 -0.0018 8 0 0 0 9.39E+07 1.64E+08 - - - 3.3751 0.9998 221125_WJC_METTL3_EV_vs_WT_F07.04991.04991.2 0.000452 22-Dec R.K[136.11]TVGVEPAADGK[136.11].G "sp|P46779|RL28_HUMAN,tr|H0YMF4|H0YMF4_HUMAN,tr|H0YLP6|H0YLP6_HUMAN,tr|H0YKD8|H0YKD8_HUMAN" 4 1186.6529 1.59 94036 4991 2 1186.654449 594.3337 60S ribosomal protein L28 OS=Homo sapiens OX=9606 GN=RPL28 PE=1 SV=3 6.07 1462.4 - 858616 - - - 1.3458 - 2.465 0.478 - 384.3 1 2 0 0.0016 12 0 0 0 9.49E+06 5.98E+06 - - - 4.9448 0.9993 221125_WJC_METTL3_EV_vs_WT_F07.04994.04994.2 0.0356 20-Aug R.ELEDSSGDQGR.C "sp|Q9BVS5|TR61B_HUMAN,tr|F8WDR2|F8WDR2_HUMAN" 2 1191.5004 1.93 94038 4994 2 1191.499784 596.7575 "tRNA (adenine(58)-N(1))-methyltransferase, mitochondrial OS=Homo sapiens OX=9606 GN=TRMT61B PE=1 SV=2" 3.92 1462.8 - 493199 - - - -0.4952 - 1.634 0.319 - 199.8 1 2 0 -0.0006 11 0 0 0 4.61E+06 2.39E+06 - - - 2.7253 0.9987 221125_WJC_METTL3_EV_vs_WT_F07.04999.04999.2 0.0063 16-Oct R.HFSAADASR.V "sp|P11441|UBL4A_HUMAN,tr|Q5HY81|Q5HY81_HUMAN" 2 960.4413 1.45 94041 4999 2 960.437878 481.2279 Ubiquitin-like protein 4A OS=Homo sapiens OX=9606 GN=UBL4A PE=1 SV=1 6.74 1463.3 - 852977 - - - -3.6077 - 1.901 0.448 - 274.5 1 2 0 -0.0035 9 0 0 0 1.75E+08 1.21E+08 - - - 4.2073 0.9921 221125_WJC_METTL3_EV_vs_WT_F07.05008.05008.2 0.0817 14-Aug R.K[136.11]LQELSSK[136.11].A "sp|P49327|FAS_HUMAN,tr|A0A0U1RQF0|A0A0U1RQF0_HUMAN" 2 947.5622 0.59 94046 5008 2 947.558862 474.7884 Fatty acid synthase OS=Homo sapiens OX=9606 GN=FASN PE=1 SV=3 8.59 1464.4 - 2.39E+06 - - - -3.5713 - 1.6 0.241 - 253.8 1 2 0 -0.0034 8 0 0 0 3.01E+07 5.14E+07 - - - 2.2375 0.9999 221125_WJC_METTL3_EV_vs_WT_F07.05010.05010.2 4.75E-06 14-Sep R.DGSHADFR.G "sp|P78332|RBM6_HUMAN,tr|F8WCA5|F8WCA5_HUMAN,tr|E9PGM9|E9PGM9_HUMAN" 3 903.3835 1.16 94047 5010 2 903.383507 452.699 RNA-binding protein 6 OS=Homo sapiens OX=9606 GN=RBM6 PE=1 SV=5 5.21 1464.6 - 369338 - - - 0.0144 - 1.793 0.556 - 332.7 1 2 0 0 8 0 0 0 9.64E+06 8.32E+06 - - - 4.9086 0.9957 221125_WJC_METTL3_EV_vs_WT_F07.05013.05013.2 0.00567 18-Dec K.LHEANNELQK.K "sp|Q86VS8|HOOK3_HUMAN,tr|H0YDM4|H0YDM4_HUMAN" 2 1194.5993 15.55 94049 5013 2 1194.606149 598.3069 Protein Hook homolog 3 OS=Homo sapiens OX=9606 GN=HOOK3 PE=1 SV=2 5.4 1464.9 - 755629 - - - 5.7333 - 2.119 0.482 - 464.7 1 2 0 0.0068 10 0 0 0 1.31E+07 8.44E+05 - - - 4.695 0.9995 221125_WJC_METTL3_EV_vs_WT_F07.05015.05015.3 0.0015 Sep-36 K.LHEANNELQK.K "sp|Q86VS8|HOOK3_HUMAN,tr|H0YDM4|H0YDM4_HUMAN" 2 1194.5993 5.69 94050 5015 3 1194.596492 399.207 Protein Hook homolog 3 OS=Homo sapiens OX=9606 GN=HOOK3 PE=1 SV=2 5.4 1465.1 - 4.60E+06 - - - -2.3506 - 1.876 0.377 - 152.1 1 2 0 -0.0028 10 0 0 0 7.62E+07 1.34E+07 - - - 4.5798 0.9999 221125_WJC_METTL3_EV_vs_WT_F07.05017.05017.2 0.000102 16-Nov R.YGDGPR[166.11]PPK[136.11].M sp|Q08211|DHX9_HUMAN 1 1003.5206 1.25 94051 5017 2 1003.519945 502.7676 ATP-dependent RNA helicase A OS=Homo sapiens OX=9606 GN=DHX9 PE=1 SV=4 8.59 1465.3 - 4.60E+06 - - - -0.6527 - 2 0.552 - 305.5 1 2 0 -0.0007 9 0 0 0 9.55E+07 7.61E+07 - - - 5.1232 0.9996 221125_WJC_METTL3_EV_vs_WT_F07.05021.05021.2 0.0178 18-Nov K.GTQTGVEQPR.L sp|Q96T58|MINT_HUMAN 1 1071.5309 59.47 94053 5021 2 1071.532298 536.7727 Msx2-interacting protein OS=Homo sapiens OX=9606 GN=SPEN PE=1 SV=1 6 1465.8 - 4.47E+06 - - - 1.3177 - 2.205 0.345 - 669.6 1 2 0 0.0014 10 0 0 0 8.16E+07 1.37E+06 - - - 3.7959 0.9982 221125_WJC_METTL3_EV_vs_WT_F07.05023.05023.2 0.0163 14-Jul R.KLQELSSK.A "sp|P49327|FAS_HUMAN,tr|A0A0U1RQF0|A0A0U1RQF0_HUMAN" 2 931.5338 0.39 94055 5023 2 931.532782 466.7742 Fatty acid synthase OS=Homo sapiens OX=9606 GN=FASN PE=1 SV=3 8.59 1465.9 - 3.22E+06 - - - -1.1422 - 1.704 0.192 - 163 1 2 0 -0.0011 8 0 0 0 4.08E+07 1.04E+08 - - - 2.0662 1 221125_WJC_METTL3_EV_vs_WT_F07.05024.05024.2 2.79E-06 15/24 R.SQAAAAAAAPGSR.S "sp|P0CG31|Z286B_HUMAN,sp|A0A2Z4LIS9|FXO3B_HUMAN" 2 1127.5683 2.6 94056 5024 2 1127.565361 564.7914 Putative zinc finger protein 286B OS=Homo sapiens OX=9606 GN=ZNF286B PE=5 SV=1 9.47 1466 - 1.27E+06 - - - -2.6366 - 3.008 0.54 - 1054.3 1 2 0 -0.003 13 0 0 0 1.77E+07 6.82E+06 - - - 5.855 0.925 221125_WJC_METTL3_EV_vs_WT_F07.05036.05036.2 0.0547 16-Sep K.KLENDTISK.Q sp|Q16204|CCDC6_HUMAN 1 1046.5608 0.95 94066 5036 2 1046.554487 524.2877 Coiled-coil domain-containing protein 6 OS=Homo sapiens OX=9606 GN=CCDC6 PE=1 SV=2 6.07 1467.5 - 591154 - - - -6.0216 - 1.745 0.152 - 279.7 1 2 0 -0.0063 9 0 0 0 8.10E+06 8.53E+06 - - - 1.7724 0.9993 221125_WJC_METTL3_EV_vs_WT_F07.05040.05040.3 0.0852 Oct-32 R.FQEAEER[166.11]PK[136.11].M "sp|Q92598|HS105_HUMAN,tr|A0A0A0MSM0|A0A0A0MSM0_HUMAN" 2 1150.5738 0.001 94068 5040 3 1150.571253 384.5319 Heat shock protein 105 kDa OS=Homo sapiens OX=9606 GN=HSPH1 PE=1 SV=1 4.79 1468 - 1.48E+07 - - - -2.1763 - 1.838 0.337 - 101.5 1 2 0 -0.0025 9 0 0 0 0.00E+00 5.83E+08 - - - 4.131 0.8689 221125_WJC_METTL3_EV_vs_WT_F07.05042.05042.2 0.0453 16-Jul S.SSASPQEER.T "sp|Q9C0C7|AMRA1_HUMAN,tr|A0A075B6T1|A0A075B6T1_HUMAN" 2 989.4414 999 94070 5042 2 989.440801 495.728 Activating molecule in BECN1-regulated autophagy protein 1 OS=Homo sapiens OX=9606 GN=AMBRA1 PE=1 SV=2 4.53 1468.1 - 2.04E+06 - - - -0.6084 - 1.274 0.259 - 119.4 1 1 0 -0.0006 9 0 0 0 2.46E+07 0.00E+00 - - - 1.6544 0.9696 221125_WJC_METTL3_EV_vs_WT_F07.05043.05043.2 0.293 14-Aug R.TRNEFVQK.G "sp|Q86U86|PB1_HUMAN,tr|H0Y5B5|H0Y5B5_HUMAN,tr|E7EVG2|E7EVG2_HUMAN,tr|C9JPI5|C9JPI5_HUMAN" 4 1020.5352 1.59 94071 5043 2 1020.535621 511.2749 Protein polybromo-1 OS=Homo sapiens OX=9606 GN=PBRM1 PE=1 SV=1 8.41 1468.2 - 1.82E+06 - - - 0.3704 - 1.663 0.135 - 316.7 1 2 1 0.0004 8 0 0 0 1.87E+07 1.18E+07 - - - 1.572 0.8296 221125_WJC_METTL3_EV_vs_WT_F07.05044.05044.2 0.484 16-May K.KATQASQEY.- sp|P16104|H2AX_HUMAN 1 1024.4825 2.15 94072 5044 2 1024.478939 513.2485 Histone H2AX OS=Homo sapiens OX=9606 GN=H2AX PE=1 SV=2 6 1468.3 - 1.20E+06 - - - -3.514 - 1.032 0.102 - 91.9 1 2 0 -0.0036 9 0 0 0 6.31E+07 2.93E+07 - - - -0.1156 0.9941 221125_WJC_METTL3_EV_vs_WT_F07.05045.05045.2 2.65E-05 20-Nov K.SVESTSPEPSK[136.11].L sp|P18583|SON_HUMAN 1 1154.5546 1.83 94073 5045 2 1154.547735 578.2846 Protein SON OS=Homo sapiens OX=9606 GN=SON PE=1 SV=4 4.53 1468.4 - 1.18E+06 - - - -5.9876 - 2.014 0.476 - 302.7 1 2 0 -0.0069 11 0 0 0 1.33E+08 7.27E+07 - - - 4.4486 0.9999 221125_WJC_METTL3_EV_vs_WT_F07.05048.05048.2 1.30E-05 20-Oct K.SVESTSPEPSK.L sp|P18583|SON_HUMAN 1 1146.5404 1.83 94074 5048 2 1146.539932 574.2775 Protein SON OS=Homo sapiens OX=9606 GN=SON PE=1 SV=4 4.53 1468.8 - 2.94E+06 - - - -0.45 - 2.104 0.539 - 261.8 1 2 0 -0.0005 11 0 0 0 1.34E+08 7.28E+07 - - - 5.0342 0.9997 221125_WJC_METTL3_EV_vs_WT_F07.05050.05050.2 0.000223 16-Sep K.DNTAQQISK.V "sp|P48594|SPB4_HUMAN,tr|C9JZ65|C9JZ65_HUMAN,tr|H0Y5H9|H0Y5H9_HUMAN" 3 1003.4934 25.84 94076 5050 2 1003.492112 502.754 Serpin B4 OS=Homo sapiens OX=9606 GN=SERPINB4 PE=1 SV=2 5.84 1468.9 - 2.43E+06 - - - -1.3214 - 1.636 0.494 - 229.1 1 2 0 -0.0013 9 0 0 0 3.01E+07 1.16E+06 - - - 4.1134 0.9871 221125_WJC_METTL3_EV_vs_WT_F07.05052.05052.2 1.13E-05 13/22 Q.TLGQAQAHSQEQ.- sp|Q96I24|FUBP3_HUMAN 1 1296.6058 - 94078 5052 2 1296.603024 649.3102 Far upstream element-binding protein 3 OS=Homo sapiens OX=9606 GN=FUBP3 PE=1 SV=2 5.21 1469.1 - 1.86E+06 - - - -2.1734 - 2.296 0.577 - 304.8 1 1 0 -0.0028 12 0 0 0 - - - - - 5.4888 0.9997 221125_WJC_METTL3_EV_vs_WT_F07.05053.05053.2 0.00266 18-Sep K.TSNSLTEDSK[136.11].M "sp|Q12888|TP53B_HUMAN,tr|H7C3N7|H7C3N7_HUMAN,tr|A6NNK5|A6NNK5_HUMAN,tr|C9JXV0|C9JXV0_HUMAN" 4 1088.5077 745.37 94079 5053 2 1088.507063 545.2611 TP53-binding protein 1 OS=Homo sapiens OX=9606 GN=TP53BP1 PE=1 SV=2 4.37 1469.2 - 866037 - - - -0.5834 - 1.786 0.418 - 218.4 1 2 0 -0.0006 10 0 0 0 1.66E+10 2.23E+07 - - - 3.747 0.841 221125_WJC_METTL3_EV_vs_WT_F07.05055.05055.2 2.28 16-Jun K.HILQQQETR[166.11].L sp|P42694|HELZ_HUMAN 1 1161.613 0.02 94081 5055 2 1161.608363 581.8138 Probable helicase with zinc finger domain OS=Homo sapiens OX=9606 GN=HELZ PE=1 SV=2 6.75 1469.5 - 285685 - - - -3.9833 - 1.169 0.108 - 119 2 2 0 -0.0046 9 0 0 0 1.27E+05 5.62E+06 - - - 0.1545 0.9998 221125_WJC_METTL3_EV_vs_WT_F07.05059.05059.2 0.00504 14-Sep R.KVPEVTEK.K "sp|Q9BRJ6|CG050_HUMAN,tr|C9JQV0|C9JQV0_HUMAN" 2 928.5229 1.07 94083 5059 2 928.522271 465.2687 Uncharacterized protein C7orf50 OS=Homo sapiens OX=9606 GN=C7orf50 PE=1 SV=1 6.14 1470 - 1.56E+06 - - - -0.728 - 1.962 0.401 - 285.7 1 2 0 -0.0007 8 0 0 0 2.35E+07 2.20E+07 - - - 4.0352 0.955 221125_WJC_METTL3_EV_vs_WT_F07.05066.05066.2 11.9 12-Jun K.HSFYNNK.C sp|Q9UGR2|Z3H7B_HUMAN 1 908.4141 1.07 94090 5066 2 908.41289 455.2143 Zinc finger CCCH domain-containing protein 7B OS=Homo sapiens OX=9606 GN=ZC3H7B PE=1 SV=2 8.6 1470.7 - 289545 - - - -1.2946 - 0.787 0.21 - 106.2 1 2 0 -0.0012 7 0 0 0 3.02E+06 2.84E+06 - - - -0.1673 0.9994 221125_WJC_METTL3_EV_vs_WT_F07.05071.05071.2 0.399 16-Oct R.K[136.11]QAGVAIGR[166.11].L sp|Q7RTV0|PHF5A_HUMAN 1 916.5573 1.26 94093 5071 2 916.556425 459.2859 PHD finger-like domain-containing protein 5A OS=Homo sapiens OX=9606 GN=PHF5A PE=1 SV=1 11 1471.3 - 1.27E+06 - - - -0.9754 - 1.693 0.338 - 341.9 1 2 0 -0.0009 9 0 0 0 1.77E+07 1.41E+07 - - - 3.0604 0.9999 221125_WJC_METTL3_EV_vs_WT_F07.05073.05073.2 4.46E-06 14/24 R.GGNIGDGGGAADR[166.11].V "sp|P55072|TERA_HUMAN,tr|A0A7P0Z4C6|A0A7P0Z4C6_HUMAN,tr|A0A7P0T8Q5|A0A7P0T8Q5_HUMAN,tr|C9JUP7|C9JUP7_HUMAN,tr|A0A7P0TAW3|A0A7P0TAW3_HUMAN,tr|A0A7I2V540|A0A7I2V540_HUMAN,tr|A0A7P0T8A3|A0A7P0T8A3_HUMAN,tr|A0A7P0TAQ1|A0A7P0TAQ1_HUMAN" 8 1125.5038 1.12 94095 5073 2 1125.503359 563.7592 Transitional endoplasmic reticulum ATPase OS=Homo sapiens OX=9606 GN=VCP PE=1 SV=4 4.21 1471.5 - 1.20E+06 - - - -0.4211 - 2.48 0.582 - 716.9 1 2 0 -0.0005 13 0 0 0 5.70E+07 5.11E+07 - - - 5.6706 1 221125_WJC_METTL3_EV_vs_WT_F07.05074.05074.2 3.58E-07 24-Dec R.GGNIGDGGGAADR.V "sp|P55072|TERA_HUMAN,tr|A0A7P0Z4C6|A0A7P0Z4C6_HUMAN,tr|A0A7P0T8Q5|A0A7P0T8Q5_HUMAN,tr|C9JUP7|C9JUP7_HUMAN,tr|A0A7P0TAW3|A0A7P0TAW3_HUMAN,tr|A0A7I2V540|A0A7I2V540_HUMAN,tr|A0A7P0T8A3|A0A7P0T8A3_HUMAN,tr|A0A7P0TAQ1|A0A7P0TAQ1_HUMAN" 8 1115.4956 1.11 94096 5074 2 1115.494489 558.7551 Transitional endoplasmic reticulum ATPase OS=Homo sapiens OX=9606 GN=VCP PE=1 SV=4 4.21 1471.6 - 1.06E+06 - - - -0.9628 - 2.548 0.621 - 491.4 1 2 0 -0.0011 13 0 0 0 5.67E+07 5.11E+07 - - - 6.0279 0.9998 221125_WJC_METTL3_EV_vs_WT_F07.05076.05076.2 0.000814 18-Oct R.NGSEGNITTR.L sp|P39880|CUX1_HUMAN 1 1047.4945 0.47 94098 5076 2 1047.493302 524.7545 Homeobox protein cut-like 1 OS=Homo sapiens OX=9606 GN=CUX1 PE=1 SV=3 6 1471.8 - 929745 - - - -1.1446 - 2.369 0.467 - 546.6 1 2 0 -0.0012 10 0 0 0 6.84E+07 1.46E+08 - - - 4.8973 0.9997 221125_WJC_METTL3_EV_vs_WT_F07.05077.05077.2 1.42E-06 13/22 R.ASVAAQQQEEAR.R "sp|Q86UK7|ZN598_HUMAN,tr|H3BQQ2|H3BQQ2_HUMAN,tr|H3BPG6|H3BPG6_HUMAN" 3 1286.6215 161.34 94099 5077 2 1286.624887 644.318 E3 ubiquitin-protein ligase ZNF598 OS=Homo sapiens OX=9606 GN=ZNF598 PE=1 SV=1 4.53 1472 - 541751 - - - 2.6387 - 2.649 0.536 - 735.1 1 2 0 0.0034 12 0 0 0 1.47E+07 9.13E+04 - - - 5.5621 1 221125_WJC_METTL3_EV_vs_WT_F07.05078.05078.2 0.000109 26-Dec R.VESGGPGTSAASAR[166.11].R sp|Q9BU76|MMTA2_HUMAN 1 1255.6032 1.11 94100 5078 2 1255.601394 628.8089 Multiple myeloma tumor-associated protein 2 OS=Homo sapiens OX=9606 GN=MMTAG2 PE=1 SV=1 5.97 1472.1 - 412534 - - - -1.4487 - 2.712 0.582 - 390.7 1 2 0 -0.0018 14 0 0 0 3.74E+07 3.36E+07 - - - 5.8427 0.9998 221125_WJC_METTL3_EV_vs_WT_F07.05079.05079.2 2.70E-08 14/26 K.LEGNSPQGSNQGVK[136.11].L sp|P61006|RAB8A_HUMAN 1 1421.699 1.21 94101 5079 2 1421.696881 711.8568 Ras-related protein Rab-8A OS=Homo sapiens OX=9606 GN=RAB8A PE=1 SV=1 6 1472.2 - 377594 - - - -1.5052 - 2.504 0.48 - 585.1 1 2 0 -0.0021 14 0 0 0 5.21E+06 4.29E+06 - - - 4.889 1 221125_WJC_METTL3_EV_vs_WT_F07.05080.05080.2 9.30E-07 18-Sep K.NTNEEDDEVR[166.11].E "sp|P49959|MRE11_HUMAN,tr|F8W7U8|F8W7U8_HUMAN" 2 1229.5036 1.69 94102 5080 2 1229.501517 615.7591 Double-strand break repair protein MRE11 OS=Homo sapiens OX=9606 GN=MRE11 PE=1 SV=3 3.83 1472.4 - 358908 - - - -1.6608 - 2.103 0.652 - 378.3 1 2 0 -0.002 10 0 0 0 4.74E+06 2.81E+06 - - - 5.931 0.9999 221125_WJC_METTL3_EV_vs_WT_F07.05087.05087.2 3.74E-06 18-Oct R.NGSEGNITTR[166.11].L sp|P39880|CUX1_HUMAN 1 1057.5028 1.05 94107 5087 2 1057.502682 529.7587 Homeobox protein cut-like 1 OS=Homo sapiens OX=9606 GN=CUX1 PE=1 SV=3 6 1473.1 - 2.77E+06 - - - -0.0842 - 2.295 0.588 - 553.6 1 2 0 -0.0001 10 0 0 0 4.36E+07 4.17E+07 - - - 5.7028 1 221125_WJC_METTL3_EV_vs_WT_F07.05088.05088.3 1.58E-07 Dec-32 K.EYVTC[160.03]HTC[160.03]R[166.11].S sp|P20042|IF2B_HUMAN 1 1234.5098 0.87 94108 5088 3 1234.50893 412.5106 Eukaryotic translation initiation factor 2 subunit 2 OS=Homo sapiens OX=9606 GN=EIF2S2 PE=1 SV=2 6.82 1473.2 - 1.09E+06 - - - -0.7428 - 2.589 0.521 - 388 1 2 0 -0.0009 9 0 0 0 6.95E+06 7.99E+06 - - - 7.2153 1 221125_WJC_METTL3_EV_vs_WT_F07.05089.05089.2 3.77E-05 15/26 R.VESGGPGTSAASAR.R sp|Q9BU76|MMTA2_HUMAN 1 1245.5949 1.12 94109 5089 2 1245.595066 623.8047 Multiple myeloma tumor-associated protein 2 OS=Homo sapiens OX=9606 GN=MMTAG2 PE=1 SV=1 5.97 1473.3 - 966250 - - - 0.0987 - 2.882 0.604 - 810.9 1 2 0 0.0001 14 0 0 0 3.74E+07 3.35E+07 - - - 6.1583 1 221125_WJC_METTL3_EV_vs_WT_F07.05091.05091.2 3.14E-07 15/26 K.LEGNSPQGSNQGVK.L sp|P61006|RAB8A_HUMAN 1 1413.6848 1.21 94111 5091 2 1413.684732 707.8497 Ras-related protein Rab-8A OS=Homo sapiens OX=9606 GN=RAB8A PE=1 SV=1 6 1473.6 - 591307 - - - -0.063 - 2.616 0.599 - 689.5 1 2 0 -0.0001 14 0 0 0 5.21E+06 4.29E+06 - - - 5.8784 0.9738 221125_WJC_METTL3_EV_vs_WT_F07.05092.05092.2 2.12 14-Jul R.HPSPELSR.L "sp|O75592|MYCB2_HUMAN,tr|A0A804HL12|A0A804HL12_HUMAN,tr|A0A499FJI4|A0A499FJI4_HUMAN,tr|A0A804HIR9|A0A804HIR9_HUMAN,tr|A0A804HJ25|A0A804HJ25_HUMAN,tr|A0A804HKQ1|A0A804HKQ1_HUMAN" 6 921.4668 1.05 94112 5092 2 921.467877 461.7407 E3 ubiquitin-protein ligase MYCBP2 OS=Homo sapiens OX=9606 GN=MYCBP2 PE=1 SV=4 6.75 1473.7 - 452182 - - - 1.1373 - 1.34 0.038 - 146 1 2 0 0.001 8 0 0 0 5.51E+06 5.23E+06 - - - 0.204 0.9998 221125_WJC_METTL3_EV_vs_WT_F07.05096.05096.2 0.00323 16-Oct K.K[136.11]ISTVVSSK[136.11].E "sp|P37108|SRP14_HUMAN,tr|H0YLA2|H0YLA2_HUMAN" 2 963.5935 1.54 94114 5096 2 963.593503 482.804 Signal recognition particle 14 kDa protein OS=Homo sapiens OX=9606 GN=SRP14 PE=1 SV=2 10 1474.2 - 1.17E+07 - - - -0.0457 - 1.982 0.383 - 372.6 1 2 0 0 9 0 0 0 1.61E+08 1.04E+08 - - - 3.849 1 221125_WJC_METTL3_EV_vs_WT_F07.05097.05097.3 1.94E-05 13/32 K.EYVTC[160.03]HTC[160.03]R.S sp|P20042|IF2B_HUMAN 1 1224.5016 0.87 94115 5097 3 1224.501262 409.1745 Eukaryotic translation initiation factor 2 subunit 2 OS=Homo sapiens OX=9606 GN=EIF2S2 PE=1 SV=2 6.82 1474.3 - 1.12E+06 - - - -0.2572 - 2.378 0.549 - 359.2 1 2 0 -0.0003 9 0 0 0 6.95E+06 7.99E+06 - - - 7.2714 0.9997 221125_WJC_METTL3_EV_vs_WT_F07.05103.05103.2 0.000115 20-Oct K.STSTPTSPGPR.T "sp|Q8WWM7|ATX2L_HUMAN,tr|A0A0C4DGL7|A0A0C4DGL7_HUMAN,tr|H3BUF6|H3BUF6_HUMAN,tr|H3BRB0|H3BRB0_HUMAN" 4 1086.5306 0.74 94121 5103 2 1086.531275 544.2726 Ataxin-2-like protein OS=Homo sapiens OX=9606 GN=ATXN2L PE=1 SV=2 9.47 1474.9 - 502342 - - - 0.6654 - 1.759 0.452 - 325.6 1 2 0 0.0007 11 0 0 0 1.78E+08 2.40E+08 - - - 3.907 0.9999 221125_WJC_METTL3_EV_vs_WT_F07.05104.05104.2 1.25E-05 18-Oct K.NTNEEDDEVR.E "sp|P49959|MRE11_HUMAN,tr|F8W7U8|F8W7U8_HUMAN" 2 1219.4953 1.69 94122 5104 2 1219.49498 610.7549 Double-strand break repair protein MRE11 OS=Homo sapiens OX=9606 GN=MRE11 PE=1 SV=3 3.83 1475 - 447584 - - - -0.2534 - 1.912 0.555 - 484.6 1 2 0 -0.0003 10 0 0 0 4.74E+06 2.81E+06 - - - 4.9493 0.9957 221125_WJC_METTL3_EV_vs_WT_F07.05110.05110.3 0.295 Nov-36 K.TYIPPK[136.11]GETK[136.11].K "sp|B2RPK0|HGB1A_HUMAN,sp|P09429|HMGB1_HUMAN,tr|Q5T7C4|Q5T7C4_HUMAN" 3 1148.6412 0.001 94126 5110 3 1148.641182 383.8877 Putative high mobility group protein B1-like 1 OS=Homo sapiens OX=9606 GN=HMGB1P1 PE=5 SV=1 8.17 1475.7 - 2.31E+07 - - - -0.0374 - 1.945 0.258 - 163.3 1 2 1 0 10 0 0 0 0.00E+00 6.60E+08 - - - 3.3593 0.9845 221125_WJC_METTL3_EV_vs_WT_F07.05113.05113.2 2.75 12-Jul K.K[136.11]SYHLNK[136.11].S "sp|Q5K651|SAMD9_HUMAN,tr|C9JKF1|C9JKF1_HUMAN" 2 904.5102 0.2 94129 5113 2 904.509114 453.2624 Sterile alpha motif domain-containing protein 9 OS=Homo sapiens OX=9606 GN=SAMD9 PE=1 SV=1 9.7 1475.9 - 1.18E+06 - - - -1.1465 - 1.507 0.02 - 258.5 1 2 0 -0.001 7 0 0 0 3.18E+06 1.58E+07 - - - 0.4879 0.999 221125_WJC_METTL3_EV_vs_WT_F07.05115.05115.2 0.0104 14-Nov K.HALSYNQR[166.11].Q "sp|Q96SB8|SMC6_HUMAN,tr|C9JMN1|C9JMN1_HUMAN" 2 997.4969 1.58 94131 5115 2 997.500022 499.7557 Structural maintenance of chromosomes protein 6 OS=Homo sapiens OX=9606 GN=SMC6 PE=1 SV=2 8.75 1476.2 - 782739 - - - 3.1328 - 1.968 0.407 - 431.1 1 2 0 0.0031 8 0 0 0 8.80E+06 5.56E+06 - - - 4.088 0.9993 221125_WJC_METTL3_EV_vs_WT_F07.05117.05117.2 0.000673 14-Aug R.DGFQHPAR.L "sp|Q8IX12|CCAR1_HUMAN,tr|F5H2E6|F5H2E6_HUMAN,tr|F5H1H2|F5H1H2_HUMAN,tr|A0A0C4DGG8|A0A0C4DGG8_HUMAN,tr|F5H3E1|F5H3E1_HUMAN" 5 926.4359 3.25 94133 5117 2 926.434599 464.2252 Cell division cycle and apoptosis regulator protein 1 OS=Homo sapiens OX=9606 GN=CCAR1 PE=1 SV=2 6.74 1476.4 - 726331 - - - -1.3654 - 1.651 0.329 - 291.8 1 2 0 -0.0013 8 0 0 0 1.61E+07 4.95E+06 - - - 2.9827 0.9998 221125_WJC_METTL3_EV_vs_WT_F07.05124.05124.3 0.000161 Nov-36 K.YLDQEKEDGK.Y "sp|Q8WV92|MITD1_HUMAN,tr|B8ZZL5|B8ZZL5_HUMAN,tr|H7C3Q6|H7C3Q6_HUMAN" 3 1223.567 1.36 94138 5124 3 1223.566832 408.8629 MIT domain-containing protein 1 OS=Homo sapiens OX=9606 GN=MITD1 PE=1 SV=1 4.32 1477.3 - 2.16E+06 - - - -0.1349 - 1.925 0.52 - 114.4 1 2 1 -0.0002 10 0 0 0 2.46E+07 1.81E+07 - - - 6.2501 0.9998 221125_WJC_METTL3_EV_vs_WT_F07.05125.05125.2 0.000134 16-Sep K.SSTGC[160.03]FSNK.S sp|Q13835|PKP1_HUMAN 1 986.4127 11.55 94139 5125 2 986.41228 494.2136 Plakophilin-1 OS=Homo sapiens OX=9606 GN=PKP1 PE=1 SV=2 7.94 1477.3 - 2.81E+06 - - - -0.4714 - 1.901 0.403 - 411.5 1 2 0 -0.0005 9 0 0 0 2.44E+07 2.11E+06 - - - 3.8759 0.995 221125_WJC_METTL3_EV_vs_WT_F07.05126.05126.2 0.00451 14-Sep K.YK[136.11]EETIEK[136.11].M sp|P61254|RL26_HUMAN 1 1054.5517 1.09 94140 5126 2 1054.551157 528.2831 60S ribosomal protein L26 OS=Homo sapiens OX=9606 GN=RPL26 PE=1 SV=1 4.79 1477.4 - 5.08E+06 - - - -0.5538 - 1.847 0.31 - 233.6 1 2 1 -0.0006 8 0 0 0 5.27E+07 4.82E+07 - - - 3.181 0.9959 221125_WJC_METTL3_EV_vs_WT_F07.05128.05128.2 0.00366 16-Sep R.EK[136.11]AEELAAR[166.11].Q "sp|Q04323|UBXN1_HUMAN,tr|E9PS08|E9PS08_HUMAN,tr|A0A087WTZ5|A0A087WTZ5_HUMAN,tr|E9PJ81|E9PJ81_HUMAN" 4 1033.5523 0.85 94142 5128 2 1033.553417 517.7834 UBX domain-containing protein 1 OS=Homo sapiens OX=9606 GN=UBXN1 PE=1 SV=2 4.79 1477.5 - 1.34E+06 - - - 1.0865 - 1.866 0.389 - 280.5 1 2 1 0.0011 9 0 0 0 1.73E+07 2.03E+07 - - - 3.7185 0.9732 221125_WJC_METTL3_EV_vs_WT_F07.05129.05129.2 0.0935 14-Aug K.RGVQQLTR.L "sp|Q6P3W7|SCYL2_HUMAN,tr|F8VSC5|F8VSC5_HUMAN,tr|A0A0U1RQQ9|A0A0U1RQQ9_HUMAN" 3 956.5516 1.13 94143 5129 2 956.547391 479.2831 SCY1-like protein 2 OS=Homo sapiens OX=9606 GN=SCYL2 PE=1 SV=1 12 1477.6 - 1.05E+06 - - - -4.3605 - 1.781 0.166 - 78.7 5 2 0 -0.0042 8 0 0 0 6.61E+06 5.86E+06 - - - 1.6943 0.9945 221125_WJC_METTL3_EV_vs_WT_F07.05131.05131.2 6.17E-05 18-Oct K.YLDQEK[136.11]EDGK[136.11].Y "sp|Q8WV92|MITD1_HUMAN,tr|B8ZZL5|B8ZZL5_HUMAN,tr|H7C3Q6|H7C3Q6_HUMAN" 3 1239.5954 2.22 94145 5131 2 1239.597737 620.805 MIT domain-containing protein 1 OS=Homo sapiens OX=9606 GN=MITD1 PE=1 SV=1 4.32 1477.8 - 284120 - - - 1.8877 - 1.579 0.486 - 267 1 2 1 0.0023 10 0 0 0 5.39E+06 2.42E+06 - - - 3.9049 0.9834 221125_WJC_METTL3_EV_vs_WT_F07.05136.05136.2 0.00124 18-Sep K.TYIPPK[136.11]GETK[136.11].K "sp|B2RPK0|HGB1A_HUMAN,sp|P09429|HMGB1_HUMAN,tr|Q5T7C4|Q5T7C4_HUMAN" 3 1148.6412 0.41 94148 5136 2 1148.640917 575.3279 Putative high mobility group protein B1-like 1 OS=Homo sapiens OX=9606 GN=HMGB1P1 PE=5 SV=1 8.17 1478.4 - 4.42E+06 - - - -0.2681 - 1.382 0.281 - 239.3 1 2 1 -0.0003 10 0 0 0 3.70E+07 9.13E+07 - - - 2.0194 0.9997 221125_WJC_METTL3_EV_vs_WT_F07.05137.05137.2 0.0233 20-Sep K.SATEQSGTGIR[166.11].S "sp|O95831|AIFM1_HUMAN,tr|A0A6Q8PHJ9|A0A6Q8PHJ9_HUMAN,tr|E9PMA0|E9PMA0_HUMAN,tr|A0A7I2PK44|A0A7I2PK44_HUMAN,tr|A0A6Q8PG15|A0A6Q8PG15_HUMAN,tr|A0A6Q8PHJ4|A0A6Q8PHJ4_HUMAN,tr|A0A6Q8PHC0|A0A6Q8PHC0_HUMAN,tr|A0A6Q8PFM5|A0A6Q8PFM5_HUMAN" 8 1115.5446 0.59 94149 5137 2 1115.54437 558.7796 "Apoptosis-inducing factor 1, mitochondrial OS=Homo sapiens OX=9606 GN=AIFM1 PE=1 SV=1" 5.72 1478.4 - 3.31E+06 - - - -0.2384 - 1.977 0.39 - 377.8 1 2 0 -0.0003 11 0 0 0 2.00E+07 3.40E+07 - - - 3.7653 0.9908 221125_WJC_METTL3_EV_vs_WT_F07.05139.05139.2 0.0273 16-Aug R.EKAEELAAR.Q "sp|Q04323|UBXN1_HUMAN,tr|E9PS08|E9PS08_HUMAN,tr|A0A087WTZ5|A0A087WTZ5_HUMAN,tr|E9PJ81|E9PJ81_HUMAN" 4 1015.5298 0.82 94151 5139 2 1015.530042 508.7722 UBX domain-containing protein 1 OS=Homo sapiens OX=9606 GN=UBXN1 PE=1 SV=2 4.79 1478.5 - 2.19E+06 - - - 0.2147 - 1.611 0.29 - 232.5 1 2 1 0.0002 9 0 0 0 1.73E+07 2.11E+07 - - - 2.5624 0.9999 221125_WJC_METTL3_EV_vs_WT_F07.05140.05140.2 1.11E-06 20-Nov R.NPSSAAPVQSR[166.11].G "sp|O15027|SC16A_HUMAN,tr|A0A3F2YNX0|A0A3F2YNX0_HUMAN,tr|A0A3F2YNZ0|A0A3F2YNZ0_HUMAN,tr|F1T0I1|F1T0I1_HUMAN" 4 1122.5657 1.44 94152 5140 2 1122.565797 562.2901 Protein transport protein Sec16A OS=Homo sapiens OX=9606 GN=SEC16A PE=1 SV=4 9.75 1478.6 - 1.92E+06 - - - 0.082 - 2.23 0.546 - 482.8 1 2 0 0.0001 11 0 0 0 2.12E+07 1.48E+07 - - - 5.2433 1 221125_WJC_METTL3_EV_vs_WT_F07.05143.05143.2 2.32E-07 14/24 K.VVNGAAASQPPSK[136.11].R sp|O75533|SF3B1_HUMAN 1 1232.6605 2.27 94155 5143 2 1232.660017 617.3375 Splicing factor 3B subunit 1 OS=Homo sapiens OX=9606 GN=SF3B1 PE=1 SV=3 8.72 1479 - 1.09E+06 - - - -0.3513 - 2.597 0.582 - 533.7 1 2 0 -0.0004 13 0 0 0 7.58E+07 3.33E+07 - - - 5.7889 0.9999 221125_WJC_METTL3_EV_vs_WT_F07.05153.05153.2 0.00019 14/24 K.VVNGAAASQPPSK.R sp|O75533|SF3B1_HUMAN 1 1224.6463 1.46 94163 5153 2 1224.645773 613.3304 Splicing factor 3B subunit 1 OS=Homo sapiens OX=9606 GN=SF3B1 PE=1 SV=3 8.72 1480.2 - 4.95E+06 - - - -0.3895 - 2.616 0.486 - 556.7 1 2 0 -0.0005 13 0 0 0 4.67E+07 3.20E+07 - - - 5.0985 0.9999 221125_WJC_METTL3_EV_vs_WT_F07.05154.05154.3 0.000761 Dec-40 K.QVHPDTGISSK.A "sp|Q8N257|H2B3B_HUMAN,sp|P33778|H2B1B_HUMAN,sp|Q96A08|H2B1A_HUMAN,sp|Q5QNW6|H2B2F_HUMAN,sp|P58876|H2B1D_HUMAN,sp|Q99880|H2B1L_HUMAN,sp|P62807|H2B1C_HUMAN,sp|Q99877|H2B1N_HUMAN,sp|P57053|H2BFS_HUMAN,sp|P23527|H2B1O_HUMAN,sp|O60814|H2B1K_HUMAN,sp|Q93079|H2B1H_HUMAN,sp|Q99879|H2B1M_HUMAN,sp|Q16778|H2B2E_HUMAN,sp|P06899|H2B1J_HUMAN,tr|U3KQK0|U3KQK0_HUMAN" 16 1167.5884 1.78 94164 5154 3 1167.588359 390.2034 Histone H2B type 3-B OS=Homo sapiens OX=9606 GN=H2BU1 PE=1 SV=3 6.74 1480.2 - 3.67E+06 - - - -0.036 - 2.275 0.441 - 175.3 1 2 0 0 11 0 0 0 2.79E+07 1.56E+07 - - - 5.7918 0.9998 221125_WJC_METTL3_EV_vs_WT_F07.05155.05155.2 0.00494 16-Dec K.K[136.11]LTVNPGTK[136.11].S sp|P09874|PARP1_HUMAN 1 972.5939 1.19 94165 5155 2 972.593682 487.3042 Poly [ADP-ribose] polymerase 1 OS=Homo sapiens OX=9606 GN=PARP1 PE=1 SV=4 10 1480.3 - 1.79E+06 - - - -0.2046 - 2.346 0.349 - 473.6 1 2 0 -0.0002 9 0 0 0 4.35E+08 3.67E+08 - - - 4.0856 0.9933 221125_WJC_METTL3_EV_vs_WT_F07.05157.05157.2 0.0149 18-Nov K.TYIPPKGETK.K "sp|B2RPK0|HGB1A_HUMAN,sp|P09429|HMGB1_HUMAN,tr|Q5T7C4|Q5T7C4_HUMAN" 3 1132.6128 0.5 94167 5157 2 1132.612924 567.3137 Putative high mobility group protein B1-like 1 OS=Homo sapiens OX=9606 GN=HMGB1P1 PE=5 SV=1 8.17 1480.4 - 1.39E+06 - - - 0.0874 - 1.622 0.332 - 407.9 1 2 1 0.0001 10 0 0 0 3.46E+07 6.94E+07 - - - 2.8432 0.997 221125_WJC_METTL3_EV_vs_WT_F07.05159.05159.2 0.358 16-Aug K.LHGTVVEGR[166.11].K "sp|O43251|RFOX2_HUMAN,sp|Q9NWB1|RFOX1_HUMAN,tr|A0A6Q8PGE0|A0A6Q8PGE0_HUMAN,tr|A0A6Q8PH77|A0A6Q8PH77_HUMAN,tr|A0A286YEU2|A0A286YEU2_HUMAN,tr|A0A087X2B1|A0A087X2B1_HUMAN,tr|F8VR27|F8VR27_HUMAN,tr|B7Z1U7|B7Z1U7_HUMAN,tr|B0QYV1|B0QYV1_HUMAN,tr|A0A6Q8PHA3|A0A6Q8PHA3_HUMAN,tr|F8VZY7|F8VZY7_HUMAN,tr|B0QYY4|B0QYY4_HUMAN,tr|J3KNW3|J3KNW3_HUMAN,tr|F8VZG9|F8VZG9_HUMAN,tr|F8VRS4|F8VRS4_HUMAN,tr|A0A6Q8PFM4|A0A6Q8PFM4_HUMAN,tr|S4R469|S4R469_HUMAN,tr|A0A804HKG7|A0A804HKG7_HUMAN,tr|A0A0G2JRD1|A0A0G2JRD1_HUMAN,tr|A0A0G2JRA5|A0A0G2JRA5_HUMAN,tr|A0A804HJM2|A0A804HJM2_HUMAN,tr|I3L1D4|I3L1D4_HUMAN,tr|S4R3K7|S4R3K7_HUMAN" 23 976.5329 1.19 94169 5159 2 976.533534 489.2738 RNA binding protein fox-1 homolog 2 OS=Homo sapiens OX=9606 GN=RBFOX2 PE=1 SV=3 6.75 1480.6 - 1.03E+06 - - - 0.5991 - 1.323 0.234 - 223.7 1 2 0 0.0006 9 0 0 0 6.91E+06 5.80E+06 - - - 1.5789 0.9996 221125_WJC_METTL3_EV_vs_WT_F07.05163.05163.2 0.00194 20-Sep K.QVHPDTGISSK.A "sp|Q8N257|H2B3B_HUMAN,sp|P33778|H2B1B_HUMAN,sp|Q96A08|H2B1A_HUMAN,sp|Q5QNW6|H2B2F_HUMAN,sp|P58876|H2B1D_HUMAN,sp|Q99880|H2B1L_HUMAN,sp|P62807|H2B1C_HUMAN,sp|Q99877|H2B1N_HUMAN,sp|P57053|H2BFS_HUMAN,sp|P23527|H2B1O_HUMAN,sp|O60814|H2B1K_HUMAN,sp|Q93079|H2B1H_HUMAN,sp|Q99879|H2B1M_HUMAN,sp|Q16778|H2B2E_HUMAN,sp|P06899|H2B1J_HUMAN,tr|U3KQK0|U3KQK0_HUMAN" 16 1167.5884 999 94173 5163 2 1167.586522 584.8015 Histone H2B type 3-B OS=Homo sapiens OX=9606 GN=H2BU1 PE=1 SV=3 6.74 1481 - 494823 - - - -1.6093 - 1.936 0.407 - 258.4 1 2 0 -0.0019 11 0 0 0 4.44E+06 0.00E+00 - - - 3.8337 0.9997 221125_WJC_METTL3_EV_vs_WT_F07.05164.05164.2 0.00198 24-Aug K.ATEPAADTGAQPK[136.11].G "sp|Q9UPT8|ZC3H4_HUMAN,tr|M0QY97|M0QY97_HUMAN" 2 1263.6186 8.76 94174 5164 2 1263.618057 632.8166 Zinc finger CCCH domain-containing protein 4 OS=Homo sapiens OX=9606 GN=ZC3H4 PE=1 SV=3 4.37 1481.1 - 395538 - - - -0.4653 - 1.643 0.459 - 218 1 2 0 -0.0006 13 0 0 0 3.20E+07 3.65E+06 - - - 3.7053 0.9999 221125_WJC_METTL3_EV_vs_WT_F07.05171.05171.2 6.53E-05 14-Oct K.HEISEMNR.M "sp|P13647|K2C5_HUMAN,tr|H0YI76|H0YI76_HUMAN" 2 1014.4553 64.05 94179 5171 2 1014.455291 508.2349 "Keratin, type II cytoskeletal 5 OS=Homo sapiens OX=9606 GN=KRT5 PE=1 SV=3" 5.4 1482 - 4.94E+06 - - - 0.0128 - 1.795 0.567 - 268 1 2 0 0 8 0 0 0 1.26E+09 1.97E+07 - - - 4.9932 0.9293 221125_WJC_METTL3_EV_vs_WT_F07.05172.05172.3 0.6 Sep-32 K.LREIEENQK.R "sp|Q14683|SMC1A_HUMAN,tr|G8JLG1|G8JLG1_HUMAN,tr|A0A6Q8PHC3|A0A6Q8PHC3_HUMAN" 3 1157.6041 1.34 94180 5172 3 1157.604504 386.8753 Structural maintenance of chromosomes protein 1A OS=Homo sapiens OX=9606 GN=SMC1A PE=1 SV=2 4.79 1482 - 3.17E+06 - - - 0.3913 - 1.546 0.149 - 108.5 1 2 1 0.0005 9 0 0 0 2.25E+07 1.67E+07 - - - 1.5141 0.9987 221125_WJC_METTL3_EV_vs_WT_F07.05173.05173.2 0.000144 18-Nov K.GK[136.11]DSLYAQGK[136.11].R "sp|P83881|RL36A_HUMAN,tr|H0Y3V9|H0Y3V9_HUMAN,tr|H7BY91|H7BY91_HUMAN,tr|H0Y5B4|H0Y5B4_HUMAN,tr|J3KQN4|J3KQN4_HUMAN,tr|H7BZ11|H7BZ11_HUMAN" 6 1081.5739 0.81 94181 5173 2 1081.574017 541.7942 60S ribosomal protein L36a OS=Homo sapiens OX=9606 GN=RPL36A PE=1 SV=2 8.5 1482.1 - 2.65E+06 - - - 0.1322 - 2.337 0.47 - 356.7 1 2 1 0.0001 10 0 0 0 1.80E+07 2.23E+07 - - - 4.8818 0.8703 221125_WJC_METTL3_EV_vs_WT_F07.05174.05174.3 0.717 May-40 K.QKPITPETAEK.L "sp|P60953|CDC42_HUMAN,tr|A0A590UJK8|A0A590UJK8_HUMAN" 2 1240.6663 1.15 94182 5174 3 1240.66583 414.5627 Cell division control protein 42 homolog OS=Homo sapiens OX=9606 GN=CDC42 PE=1 SV=2 6.14 1482.1 - 2.40E+06 - - - -0.3925 - 1.285 0.145 - 23.4 18 2 0 -0.0005 11 0 0 0 8.65E+07 7.53E+07 - - - 0.2879 0.9997 221125_WJC_METTL3_EV_vs_WT_F07.05177.05177.2 0.00111 18-Oct R.IAGQVAAANK.K "sp|P39019|RS19_HUMAN,tr|A0A075B6E2|A0A075B6E2_HUMAN" 2 941.5294 1.38 94185 5177 2 941.52938 471.772 40S ribosomal protein S19 OS=Homo sapiens OX=9606 GN=RPS19 PE=1 SV=2 8.75 1482.3 - 1.68E+06 - - - -0.0531 - 2.023 0.374 - 264.8 1 2 0 -0.0001 10 0 0 0 1.23E+07 8.90E+06 - - - 3.77 0.7656 221125_WJC_METTL3_EV_vs_WT_F07.05179.05179.2 3.00E-05 18-Nov K.GKDSLYAQGK.R "sp|P83881|RL36A_HUMAN,tr|H0Y3V9|H0Y3V9_HUMAN,tr|H7BY91|H7BY91_HUMAN,tr|H0Y5B4|H0Y5B4_HUMAN,tr|J3KQN4|J3KQN4_HUMAN,tr|H7BZ11|H7BZ11_HUMAN" 6 1065.5455 0.81 94187 5179 2 1065.552446 533.78 60S ribosomal protein L36a OS=Homo sapiens OX=9606 GN=RPL36A PE=1 SV=2 8.5 1482.4 - 1.36E+06 - - - 6.5431 - 2.453 0.2 - 339.8 1 2 1 0.007 10 0 0 0 1.80E+07 2.23E+07 - - - 3.0207 0.9568 221125_WJC_METTL3_EV_vs_WT_F07.05183.05183.2 0.557 16-Sep K.LREIEENQK.R "sp|Q14683|SMC1A_HUMAN,tr|G8JLG1|G8JLG1_HUMAN,tr|A0A6Q8PHC3|A0A6Q8PHC3_HUMAN" 3 1157.6041 1.97 94191 5183 2 1157.603803 579.8093 Structural maintenance of chromosomes protein 1A OS=Homo sapiens OX=9606 GN=SMC1A PE=1 SV=2 4.79 1482.8 - 713711 - - - -0.2142 - 1.754 0.08 - 250.8 1 2 1 -0.0002 9 0 0 0 5.33E+06 2.70E+06 - - - 1.2574 0.9997 221125_WJC_METTL3_EV_vs_WT_F07.05187.05187.2 0.259 16-Oct R.NASSEEIQR.A "sp|Q9UBU9|NXF1_HUMAN,tr|E9PIN3|E9PIN3_HUMAN" 2 1032.4836 0.69 94193 5187 2 1032.483057 517.2491 Nuclear RNA export factor 1 OS=Homo sapiens OX=9606 GN=NXF1 PE=1 SV=1 4.53 1483.3 - 9.51E+06 - - - -0.5279 - 2.002 0.344 - 460 1 2 0 -0.0005 9 0 0 0 7.35E+07 1.07E+08 - - - 3.5898 0.9999 221125_WJC_METTL3_EV_vs_WT_F07.05188.05188.2 0.000489 20-Nov R.SGGGGGGGFGR.V "sp|P13647|K2C5_HUMAN,tr|F8VV57|F8VV57_HUMAN,tr|F8VU69|F8VU69_HUMAN" 3 864.3838 26.94 94194 5188 2 864.383516 433.1992 "Keratin, type II cytoskeletal 5 OS=Homo sapiens OX=9606 GN=KRT5 PE=1 SV=3" 9.47 1483.4 - 7.09E+06 - - - -0.361 - 2.334 0.501 - 597.4 1 2 0 -0.0003 11 0 0 0 1.01E+08 3.75E+06 - - - 5.0342 0.9922 221125_WJC_METTL3_EV_vs_WT_F07.05189.05189.2 0.0671 16-Oct R.VR[166.11]IEAENEK[136.11].N "sp|Q06787|FMR1_HUMAN,tr|R9WNI0|R9WNI0_HUMAN,tr|A8MQB8|A8MQB8_HUMAN,tr|A0A087WXI3|A0A087WXI3_HUMAN,tr|G3V0J0|G3V0J0_HUMAN" 5 1104.5894 1.68 94195 5189 2 1104.589686 553.302 Synaptic functional regulator FMR1 OS=Homo sapiens OX=9606 GN=FMR1 PE=1 SV=1 4.79 1483.4 - 5.82E+06 - - - 0.2526 - 1.781 0.272 - 411.8 1 2 1 0.0003 9 0 0 0 5.61E+07 3.34E+07 - - - 2.7197 0.9998 221125_WJC_METTL3_EV_vs_WT_F07.05190.05190.3 0.000138 13/40 K.VGEFSGANKEK.L sp|P10599|THIO_HUMAN 1 1164.5775 1.72 94196 5190 3 1164.577546 389.1998 Thioredoxin OS=Homo sapiens OX=9606 GN=TXN PE=1 SV=3 6.11 1483.5 - 5.56E+06 - - - 0.0378 - 2.492 0.451 - 228 1 2 1 0 11 0 0 0 6.35E+07 3.69E+07 - - - 6.1621 1 221125_WJC_METTL3_EV_vs_WT_F07.05191.05191.2 5.61E-05 15/24 K.AAATPESQEPQAK[136.11].G sp|P49006|MRP_HUMAN 1 1334.6558 0.85 94197 5191 2 1334.655664 668.3352 MARCKS-related protein OS=Homo sapiens OX=9606 GN=MARCKSL1 PE=1 SV=2 4.53 1483.5 - 4.56E+06 - - - -0.0712 - 2.909 0.598 - 863 1 2 0 -0.0001 13 0 0 0 7.99E+07 9.42E+07 - - - 6.1984 0.8269 221125_WJC_METTL3_EV_vs_WT_F07.05192.05192.3 0.941 Aug-40 K.QK[136.11]PITPETAEK[136.11].L "sp|P60953|CDC42_HUMAN,tr|A0A590UJK8|A0A590UJK8_HUMAN" 2 1256.6947 1.29 94198 5192 3 1256.693823 419.9055 Cell division control protein 42 homolog OS=Homo sapiens OX=9606 GN=CDC42 PE=1 SV=2 6.14 1483.6 - 3.26E+06 - - - -0.7114 - 1.334 0.067 - 87.1 1 2 0 -0.0009 11 0 0 0 8.60E+07 6.69E+07 - - - 0.1054 0.9999 221125_WJC_METTL3_EV_vs_WT_F07.05193.05193.3 0.00112 Oct-40 R.YIVNGSHEANK.L "sp|P55010|IF5_HUMAN,tr|H0YM54|H0YM54_HUMAN,tr|H0YLZ1|H0YLZ1_HUMAN,tr|H0YMJ8|H0YMJ8_HUMAN,tr|H0YN40|H0YN40_HUMAN" 5 1230.5993 0.77 94199 5193 3 1230.599987 411.207 Eukaryotic translation initiation factor 5 OS=Homo sapiens OX=9606 GN=EIF5 PE=1 SV=2 6.75 1483.6 - 2.86E+06 - - - 0.5583 - 2.13 0.394 - 69.8 1 2 0 0.0007 11 0 0 0 1.60E+07 2.08E+07 - - - 5.0805 0.9998 221125_WJC_METTL3_EV_vs_WT_F07.05195.05195.2 0.0457 18-Dec R.KIEVNNATAR.V "sp|O43251|RFOX2_HUMAN,sp|Q9NWB1|RFOX1_HUMAN,sp|A6NFN3|RFOX3_HUMAN,tr|A0A6Q8PGE0|A0A6Q8PGE0_HUMAN,tr|A0A6Q8PH77|A0A6Q8PH77_HUMAN,tr|A0A286YEU2|A0A286YEU2_HUMAN,tr|A0A087X2B1|A0A087X2B1_HUMAN,tr|F8VR27|F8VR27_HUMAN,tr|B7Z1U7|B7Z1U7_HUMAN,tr|B0QYV1|B0QYV1_HUMAN,tr|A0A6Q8PHA3|A0A6Q8PHA3_HUMAN,tr|A0A3B3ITL7|A0A3B3ITL7_HUMAN,tr|F8VZY7|F8VZY7_HUMAN,tr|B0QYY4|B0QYY4_HUMAN,tr|J3KNW3|J3KNW3_HUMAN,tr|F8VZG9|F8VZG9_HUMAN,tr|J3QRF4|J3QRF4_HUMAN,tr|F8VRS4|F8VRS4_HUMAN,tr|A0A6Q8PFM4|A0A6Q8PFM4_HUMAN,tr|S4R469|S4R469_HUMAN,tr|A0A804HKG7|A0A804HKG7_HUMAN,tr|A0A0G2JRD1|A0A0G2JRD1_HUMAN,tr|A0A0G2JRA5|A0A0G2JRA5_HUMAN,tr|A0A804HJM2|A0A804HJM2_HUMAN,tr|I3L1D4|I3L1D4_HUMAN,tr|S4R3K7|S4R3K7_HUMAN" 26 1114.6095 1.36 94201 5195 2 1114.609542 558.312 RNA binding protein fox-1 homolog 2 OS=Homo sapiens OX=9606 GN=RBFOX2 PE=1 SV=3 8.75 1483.7 - 2.09E+06 - - - 0.0637 - 2.525 0.317 - 523.8 1 2 0 0.0001 10 0 0 0 1.29E+08 9.51E+07 - - - 3.9678 0.9995 221125_WJC_METTL3_EV_vs_WT_F07.05196.05196.2 0.000196 14-Oct K.THIEQIQK.H "sp|Q99590|SCAFB_HUMAN,tr|F8VXG7|F8VXG7_HUMAN,tr|A0A0A0MTP7|A0A0A0MTP7_HUMAN" 3 995.54 1.08 94202 5196 2 995.540582 498.7773 Protein SCAF11 OS=Homo sapiens OX=9606 GN=SCAF11 PE=1 SV=2 6.41 1483.8 - 1.79E+06 - - - 0.5906 - 1.956 0.268 - 403.8 1 2 0 0.0006 8 0 0 0 1.64E+07 1.51E+07 - - - 3.0437 0.9974 221125_WJC_METTL3_EV_vs_WT_F07.05201.05201.2 0.00346 20-Sep K.QK[136.11]PITPETAEK[136.11].L "sp|P60953|CDC42_HUMAN,tr|A0A590UJK8|A0A590UJK8_HUMAN" 2 1256.6947 1.31 94207 5201 2 1256.698008 629.3546 Cell division control protein 42 homolog OS=Homo sapiens OX=9606 GN=CDC42 PE=1 SV=2 6.14 1484.4 - 344044 - - - 2.6188 - 1.286 0.395 - 175.2 1 2 0 0.0033 11 0 0 0 1.29E+07 9.81E+06 - - - 2.6379 0.9999 221125_WJC_METTL3_EV_vs_WT_F07.05210.05210.2 5.18E-06 18-Nov R.THTALPGAEK.L sp|Q9H7S9|ZN703_HUMAN 1 1023.5349 1.42 94214 5210 2 1023.535155 512.7747 Zinc finger protein 703 OS=Homo sapiens OX=9606 GN=ZNF703 PE=1 SV=1 6.41 1485.1 - 2.38E+06 - - - 0.2403 - 1.963 0.54 - 498.8 1 2 0 0.0002 10 0 0 0 7.44E+08 5.25E+08 - - - 4.912 1 221125_WJC_METTL3_EV_vs_WT_F07.05212.05212.2 1.12E-07 15/22 R.EGSGAQGEAEVR.H "sp|O15417|TNC18_HUMAN,tr|H9KVB4|H9KVB4_HUMAN,tr|H7C3U5|H7C3U5_HUMAN" 3 1188.5371 2.08 94216 5212 2 1188.537235 595.2758 Trinucleotide repeat-containing gene 18 protein OS=Homo sapiens OX=9606 GN=TNRC18 PE=1 SV=3 4.25 1485.2 - 1.52E+06 - - - 0.1186 - 2.338 0.646 - 834.4 1 2 0 0.0001 12 0 0 0 1.69E+07 8.16E+06 - - - 6.047 0.9997 221125_WJC_METTL3_EV_vs_WT_F07.05215.05215.2 4.75E-06 22-Nov R.EGSGAQGEAEVR[166.11].H "sp|O15417|TNC18_HUMAN,tr|H9KVB4|H9KVB4_HUMAN,tr|H7C3U5|H7C3U5_HUMAN" 3 1198.5454 2.14 94219 5215 2 1198.542135 600.28 Trinucleotide repeat-containing gene 18 protein OS=Homo sapiens OX=9606 GN=TNRC18 PE=1 SV=3 4.25 1485.5 - 796469 - - - -2.6941 - 2.293 0.591 - 425.2 1 2 0 -0.0032 12 0 0 0 1.75E+07 8.16E+06 - - - 5.5886 0.9999 221125_WJC_METTL3_EV_vs_WT_F07.05221.05221.2 0.000329 18-Nov K.QDGEC[160.03]GTLSK.G sp|Q5D862|FILA2_HUMAN 1 1093.471 21.29 94223 5221 2 1093.470363 547.7428 Filaggrin-2 OS=Homo sapiens OX=9606 GN=FLG2 PE=1 SV=1 4.37 1486.3 - 1.82E+07 - - - -0.5716 - 2.314 0.509 - 517.6 1 2 0 -0.0006 10 0 0 0 1.53E+08 7.17E+06 - - - 5.1421 0.9998 221125_WJC_METTL3_EV_vs_WT_F07.05222.05222.3 3.95E-06 13/36 R.ISEDKNPDYR.K sp|P14923|PLAK_HUMAN 1 1235.5782 14.8 94224 5222 3 1235.576948 412.8667 Junction plakoglobin OS=Homo sapiens OX=9606 GN=JUP PE=1 SV=3 4.56 1486.4 - 1.20E+07 - - - -1.0376 - 2.078 0.48 - 211.2 1 2 1 -0.0013 10 0 0 0 8.01E+07 5.41E+06 - - - 6.0272 0.9996 221125_WJC_METTL3_EV_vs_WT_F07.05223.05223.2 0.00368 18-Sep K.SAHAGTYEVR[166.11].F "sp|P51571|SSRD_HUMAN,tr|A6NLM8|A6NLM8_HUMAN" 2 1099.5286 0.56 94225 5223 2 1099.52709 550.7716 Translocon-associated protein subunit delta OS=Homo sapiens OX=9606 GN=SSR4 PE=1 SV=1 6.47 1486.4 - 7.41E+06 - - - -1.366 - 1.678 0.448 - 274.9 1 2 0 -0.0015 10 0 0 0 5.34E+07 9.49E+07 - - - 3.7942 0.9983 221125_WJC_METTL3_EV_vs_WT_F07.05224.05224.2 0.475 18-Oct R.DQALSNAQAK.V "sp|Q4VCS5|AMOT_HUMAN,tr|A6NP16|A6NP16_HUMAN,tr|E7ERM3|E7ERM3_HUMAN" 3 1044.52 1.25 94226 5224 2 1044.52092 523.2673 Angiomotin OS=Homo sapiens OX=9606 GN=AMOT PE=1 SV=1 5.84 1486.4 - 6.88E+06 - - - 0.8932 - 1.798 0.193 - 438.4 1 2 0 0.0009 10 0 0 0 5.32E+07 4.25E+07 - - - 2.1038 0.9997 221125_WJC_METTL3_EV_vs_WT_F07.05226.05226.2 0.000987 18-Sep K.AVQSTINHVK[136.11].E "sp|Q96MF7|NSE2_HUMAN,tr|E5RHW9|E5RHW9_HUMAN,tr|E5RIM1|E5RIM1_HUMAN,tr|A0A087WTZ8|A0A087WTZ8_HUMAN,tr|E5RFJ1|E5RFJ1_HUMAN" 5 1103.6179 1.51 94228 5226 2 1103.617284 552.8162 E3 SUMO-protein ligase NSE2 OS=Homo sapiens OX=9606 GN=NSMCE2 PE=1 SV=2 8.8 1486.5 - 3.28E+06 - - - -0.5192 - 1.899 0.399 - 224.8 1 2 0 -0.0006 10 0 0 0 2.82E+07 1.87E+07 - - - 3.778 0.9995 221125_WJC_METTL3_EV_vs_WT_F07.05228.05228.2 0.00537 20-Aug K.QKPITPETAEK.L "sp|P60953|CDC42_HUMAN,tr|A0A590UJK8|A0A590UJK8_HUMAN" 2 1240.6663 1.31 94230 5228 2 1240.666271 621.3404 Cell division control protein 42 homolog OS=Homo sapiens OX=9606 GN=CDC42 PE=1 SV=2 6.14 1486.7 - 1.19E+06 - - - -0.0371 - 1.383 0.42 - 126.5 1 2 0 0 11 0 0 0 1.29E+07 9.81E+06 - - - 3.0203 0.8514 221125_WJC_METTL3_EV_vs_WT_F07.05229.05229.2 1.93E-06 16-Nov L.SEDKNPDYR.K sp|P14923|PLAK_HUMAN 1 1122.4942 1.93 94231 5229 2 1122.491589 562.2544 Junction plakoglobin OS=Homo sapiens OX=9606 GN=JUP PE=1 SV=3 4.56 1486.8 - 1.07E+06 - - - -2.2958 - 2.218 0.534 - 508.2 1 1 1 -0.0026 9 0 0 0 1.97E+07 1.02E+07 - - - 5.2889 0.9508 221125_WJC_METTL3_EV_vs_WT_F07.05235.05235.3 0.00484 Nov-44 L.GALAQRPGSVSK.W "sp|Q9NXV2|KCTD5_HUMAN,tr|H3BSS5|H3BSS5_HUMAN" 2 1169.6517 4.48 94235 5235 3 1169.65073 390.8912 BTB\POZ domain-containing protein KCTD5 OS=Homo sapiens OX=9606 GN=KCTD5 PE=1 SV=1 11 1487.5 - 8.54E+06 - - - -0.8037 - 2.309 0.267 - 136.4 1 1 0 -0.0009 12 0 0 0 6.59E+07 1.47E+07 - - - 3.8361 0.9998 221125_WJC_METTL3_EV_vs_WT_F07.05236.05236.3 0.000589 14/36 K.ISEKEEVTTR.E sp|Q03252|LMNB2_HUMAN 1 1190.6143 1.22 94236 5236 3 1190.614472 397.8787 Lamin-B2 OS=Homo sapiens OX=9606 GN=LMNB2 PE=1 SV=4 4.79 1487.5 - 6.43E+06 - - - 0.1596 - 2.395 0.436 - 253.3 1 2 1 0.0002 10 0 0 0 7.89E+07 6.49E+07 - - - 5.9516 0.9996 221125_WJC_METTL3_EV_vs_WT_F07.05239.05239.2 0.17 16-Sep R.QQQEQQLAR[166.11].M "sp|Q9UPQ9|TNR6B_HUMAN,tr|H0Y720|H0Y720_HUMAN" 2 1137.5766 2.07 94239 5239 2 1137.577412 569.7956 Trinucleotide repeat-containing gene 6B protein OS=Homo sapiens OX=9606 GN=TNRC6B PE=1 SV=4 6 1487.6 - 3.27E+06 - - - 0.7103 - 2.038 0.335 - 559.1 1 2 0 0.0008 9 0 0 0 9.22E+07 4.46E+07 - - - 3.5748 0.9915 221125_WJC_METTL3_EV_vs_WT_F07.05240.05240.2 2.47E-06 18-Oct L.EEANNDLENK.L sp|P35527|K1C9_HUMAN 1 1174.5102 89.05 94240 5240 2 1174.510841 588.2624 "Keratin, type I cytoskeletal 9 OS=Homo sapiens OX=9606 GN=KRT9 PE=1 SV=3" 4 1487.7 - 2.37E+06 - - - 0.5372 - 2.049 0.499 - 488.8 1 1 0 0.0006 10 0 0 0 9.67E+07 1.09E+06 - - - 4.7288 0.9999 221125_WJC_METTL3_EV_vs_WT_F07.05241.05241.2 7.88E-06 20-Oct K.QEC[160.03]EAEASSVK.N sp|Q9P2D1|CHD7_HUMAN 1 1236.5292 1.2 94241 5241 2 1236.529541 619.2719 Chromodomain-helicase-DNA-binding protein 7 OS=Homo sapiens OX=9606 GN=CHD7 PE=1 SV=3 4.25 1487.8 - 2.35E+06 - - - 0.2499 - 2.197 0.573 - 332.3 1 2 0 0.0003 11 0 0 0 2.44E+07 2.04E+07 - - - 5.4024 0.9999 221125_WJC_METTL3_EV_vs_WT_F07.05244.05244.2 0.000125 20-Nov K.QEC[160.03]EAEASSVK[136.11].N sp|Q9P2D1|CHD7_HUMAN 1 1244.5434 1.21 94244 5244 2 1244.543342 623.279 Chromodomain-helicase-DNA-binding protein 7 OS=Homo sapiens OX=9606 GN=CHD7 PE=1 SV=3 4.25 1488 - 1.84E+06 - - - -0.0723 - 2.373 0.529 - 490.5 1 2 0 -0.0001 11 0 0 0 2.44E+07 2.01E+07 - - - 5.2859 0.9868 221125_WJC_METTL3_EV_vs_WT_F07.05245.05245.2 0.0471 18-Sep K.HVLEDSPAGK[136.11].N "sp|O75970|MPDZ_HUMAN,tr|F5H8D6|F5H8D6_HUMAN,tr|B7ZB24|B7ZB24_HUMAN,tr|F8WDQ8|F8WDQ8_HUMAN,tr|H0YGQ3|H0YGQ3_HUMAN,tr|F5H1U9|F5H1U9_HUMAN" 6 1059.544 3.06 94245 5245 2 1059.548474 530.7793 Multiple PDZ domain protein OS=Homo sapiens OX=9606 GN=MPDZ PE=1 SV=2 5.32 1488.1 - 1.67E+06 - - - 4.1999 - 1.423 0.296 - 186.3 1 2 0 0.0045 10 0 0 0 4.35E+07 1.42E+07 - - - 2.2105 0.9931 221125_WJC_METTL3_EV_vs_WT_F07.05246.05246.2 0.00177 14/22 L.GALAQRPGSVSK.W "sp|Q9NXV2|KCTD5_HUMAN,tr|H3BSS5|H3BSS5_HUMAN" 2 1169.6517 5.09 94246 5246 2 1169.651889 585.8331 BTB\POZ domain-containing protein KCTD5 OS=Homo sapiens OX=9606 GN=KCTD5 PE=1 SV=1 11 1488.2 - 1.65E+06 - - - 0.1872 - 2.754 0.442 - 605.2 1 1 0 0.0002 12 0 0 0 1.53E+07 3.00E+06 - - - 4.9711 0.9988 221125_WJC_METTL3_EV_vs_WT_F07.05248.05248.2 0.000143 22-Sep R.SGPPPSSGMSSR[166.11].V "sp|Q9NTZ6|RBM12_HUMAN,tr|A6PVI0|A6PVI0_HUMAN,tr|Q5JX62|Q5JX62_HUMAN,tr|A6PVI1|A6PVI1_HUMAN" 4 1155.5218 2.22 94248 5248 2 1155.523927 578.7682 RNA-binding protein 12 OS=Homo sapiens OX=9606 GN=RBM12 PE=1 SV=1 9.47 1488.4 - 445025 - - - 1.8477 - 1.85 0.297 - 250 1 2 0 0.0021 12 0 0 0 1.23E+07 5.54E+06 - - - 2.8526 0.9996 221125_WJC_METTL3_EV_vs_WT_F07.05252.05252.2 0.00274 16-Aug R.ESEEENLNK[136.11].S "sp|O95793|STAU1_HUMAN,tr|Q5JW30|Q5JW30_HUMAN,tr|Q5JW28|Q5JW28_HUMAN" 3 1098.492 2.33 94250 5252 2 1098.491302 550.2533 Double-stranded RNA-binding protein Staufen homolog 1 OS=Homo sapiens OX=9606 GN=STAU1 PE=1 SV=2 4.09 1488.9 - 5.54E+06 - - - -0.6791 - 1.412 0.465 - 249.6 1 2 0 -0.0007 9 0 0 0 2.07E+08 8.88E+07 - - - 3.4734 0.9997 221125_WJC_METTL3_EV_vs_WT_F07.05253.05253.2 0.00506 14/18 R.LHDIETENQK.L "sp|Q13948|CASP_HUMAN,sp|P39880|CUX1_HUMAN,tr|A0A2R8Y852|A0A2R8Y852_HUMAN,tr|A0A2R8YDI1|A0A2R8YDI1_HUMAN" 4 1225.5939 1.43 94251 5253 2 1225.592128 613.8042 Protein CASP OS=Homo sapiens OX=9606 GN=CUX1 PE=1 SV=2 4.65 1489 - 4.68E+06 - - - -1.4303 - 2.531 0.339 - 812.4 1 2 0 -0.0018 10 0 0 0 4.82E+07 3.37E+07 - - - 4.1363 0.8132 221125_WJC_METTL3_EV_vs_WT_F07.05254.05254.2 0.000284 16-Sep V.K[136.11]APGFGDNR[166.11].K "sp|P10809|CH60_HUMAN,tr|A0A7I2V2X6|A0A7I2V2X6_HUMAN,tr|A0A7I2YQK6|A0A7I2YQK6_HUMAN,tr|A0A7I2V599|A0A7I2V599_HUMAN,tr|A0A7I2V5M1|A0A7I2V5M1_HUMAN" 5 978.5002 3.59 94252 5254 2 978.504836 490.2574 "60 kDa heat shock protein, mitochondrial OS=Homo sapiens OX=9606 GN=HSPD1 PE=1 SV=2" 8.75 1489 - 5.85E+06 - - - 4.7399 - 1.791 0.428 - 305.9 1 1 0 0.0046 9 0 0 0 1.72E+08 4.79E+07 - - - 3.8867 0.968 221125_WJC_METTL3_EV_vs_WT_F07.05255.05255.2 0.0293 14-Jun R.SKYNDDIR.K sp|Q9Y3D6|FIS1_HUMAN 1 1009.4829 1.72 94253 5255 2 1009.482616 505.7487 Mitochondrial fission 1 protein OS=Homo sapiens OX=9606 GN=FIS1 PE=1 SV=2 5.68 1489.1 - 4.71E+06 - - - -0.2546 - 1.138 0.279 - 105.3 1 2 1 -0.0003 8 0 0 0 5.56E+07 3.24E+07 - - - 1.4915 0.9926 221125_WJC_METTL3_EV_vs_WT_F07.05256.05256.2 0.502 16-Aug R.R[166.11]PETISEPK[136.11].T sp|O95551|TYDP2_HUMAN 1 1073.5836 0.11 94254 5256 2 1073.582863 537.7991 Tyrosyl-DNA phosphodiesterase 2 OS=Homo sapiens OX=9606 GN=TDP2 PE=1 SV=1 6.14 1489.1 - 3.38E+06 - - - -0.6809 - 1.451 0.102 - 204.2 1 2 0 -0.0007 9 0 0 0 2.68E+06 2.52E+07 - - - 0.8711 0.9996 221125_WJC_METTL3_EV_vs_WT_F07.05257.05257.2 1.27E-06 18-Dec R.LHDIETENQK[136.11].L "sp|Q13948|CASP_HUMAN,sp|P39880|CUX1_HUMAN,tr|A0A2R8Y852|A0A2R8Y852_HUMAN,tr|A0A2R8YDI1|A0A2R8YDI1_HUMAN" 4 1233.6081 1.43 94255 5257 2 1233.604462 617.8113 Protein CASP OS=Homo sapiens OX=9606 GN=CUX1 PE=1 SV=2 4.65 1489.2 - 2.74E+06 - - - -2.9337 - 2.445 0.551 - 496.1 1 2 0 -0.0036 10 0 0 0 4.82E+07 3.37E+07 - - - 5.6051 0.9997 221125_WJC_METTL3_EV_vs_WT_F07.05258.05258.2 0.00288 20-Sep R.SAENPPSGSVR[166.11].K "sp|Q15014|MO4L2_HUMAN,tr|Q5JXX2|Q5JXX2_HUMAN,tr|Q5JXX1|Q5JXX1_HUMAN" 3 1109.5341 1.72 94256 5258 2 1109.533295 555.7743 Mortality factor 4-like protein 2 OS=Homo sapiens OX=9606 GN=MORF4L2 PE=1 SV=1 5.72 1489.2 - 2.66E+06 - - - -0.6994 - 1.972 0.397 - 265.9 1 2 0 -0.0008 11 0 0 0 8.53E+07 4.95E+07 - - - 3.81 0.9984 221125_WJC_METTL3_EV_vs_WT_F07.05259.05259.2 1.37E-05 18-Dec K.ISEKEEVTTR.E sp|Q03252|LMNB2_HUMAN 1 1190.6143 6.74 94257 5259 2 1190.613468 596.3144 Lamin-B2 OS=Homo sapiens OX=9606 GN=LMNB2 PE=1 SV=4 4.79 1489.3 - 1.97E+06 - - - -0.6837 - 2.089 0.49 - 618.4 1 2 1 -0.0008 10 0 0 0 6.13E+07 9.09E+06 - - - 4.7162 0.9982 221125_WJC_METTL3_EV_vs_WT_F07.05261.05261.2 1.69E-05 18-Dec K.ISEK[136.11]EEVTTR[166.11].E sp|Q03252|LMNB2_HUMAN 1 1208.6368 6.7 94259 5261 2 1208.637272 605.3257 Lamin-B2 OS=Homo sapiens OX=9606 GN=LMNB2 PE=1 SV=4 4.79 1489.5 - 1.29E+06 - - - 0.4302 - 2.033 0.469 - 560.8 1 2 1 0.0005 10 0 0 0 6.09E+07 9.09E+06 - - - 4.4853 0.9992 221125_WJC_METTL3_EV_vs_WT_F07.05266.05266.2 0.00687 14-Jun K.NHPAPFSK[136.11].V "sp|O95757|HS74L_HUMAN,tr|D6RJ96|D6RJ96_HUMAN,tr|E9PDE8|E9PDE8_HUMAN" 3 904.4647 0.35 94262 5266 2 904.463832 453.2396 Heat shock 70 kDa protein 4L OS=Homo sapiens OX=9606 GN=HSPA4L PE=1 SV=3 8.76 1490 - 3.69E+06 - - - -0.9055 - 1.376 0.364 - 143.7 1 2 0 -0.0008 8 0 0 0 2.48E+07 7.00E+07 - - - 2.6919 0.9984 221125_WJC_METTL3_EV_vs_WT_F07.05268.05268.2 0.00103 18-Sep R.NPPGASTYNK[136.11].N "sp|Q9BUJ2|HNRL1_HUMAN,tr|A0A0A0MRA5|A0A0A0MRA5_HUMAN,tr|M0R3F1|M0R3F1_HUMAN,tr|B7Z4B8|B7Z4B8_HUMAN" 4 1055.5127 1.56 94264 5268 2 1055.509457 528.7636 Heterogeneous nuclear ribonucleoprotein U-like protein 1 OS=Homo sapiens OX=9606 GN=HNRNPUL1 PE=1 SV=2 8.59 1490.1 - 2.38E+06 - - - -3.0942 - 1.529 0.434 - 220.1 1 2 0 -0.0033 10 0 0 0 5.62E+07 3.60E+07 - - - 3.4307 0.9993 221125_WJC_METTL3_EV_vs_WT_F07.05273.05273.2 0.0972 14-Aug K.YEDEINKR.T "sp|P48668|K2C6C_HUMAN,sp|P05787|K2C8_HUMAN,sp|Q01546|K22O_HUMAN,sp|Q7Z794|K2C1B_HUMAN,sp|P12035|K2C3_HUMAN,sp|P04264|K2C1_HUMAN,sp|P04259|K2C6B_HUMAN,sp|P13647|K2C5_HUMAN,sp|P35908|K22E_HUMAN,sp|O95678|K2C75_HUMAN,sp|P02538|K2C6A_HUMAN,tr|F8VUG2|F8VUG2_HUMAN,tr|F8W0C6|F8W0C6_HUMAN,tr|F8VP67|F8VP67_HUMAN,tr|F8W1U3|F8W1U3_HUMAN,tr|H0YIN9|H0YIN9_HUMAN" 16 1065.5091 75.59 94267 5273 2 1065.508115 533.7618 "Keratin, type II cytoskeletal 6C OS=Homo sapiens OX=9606 GN=KRT6C PE=1 SV=3" 4.68 1490.7 - 1.82E+07 - - - -0.9132 - 1.759 0.276 - 191.5 1 2 0 -0.001 8 0 0 0 1.96E+09 2.60E+07 - - - 2.7825 0.999 221125_WJC_METTL3_EV_vs_WT_F07.05274.05274.2 0.299 16-Sep K.TQELETTQK[136.11].H "sp|P52732|KIF11_HUMAN,tr|A0A7I2YQY4|A0A7I2YQY4_HUMAN,tr|A0A7I2V3A9|A0A7I2V3A9_HUMAN,tr|A0A7I2V3V3|A0A7I2V3V3_HUMAN" 4 1084.5492 5.56 94268 5274 2 1084.548616 543.2819 Kinesin-like protein KIF11 OS=Homo sapiens OX=9606 GN=KIF11 PE=1 SV=2 4.53 1490.7 - 6.21E+06 - - - -0.5099 - 1.857 0.211 - 342.8 1 2 0 -0.0006 9 0 0 0 1.44E+09 2.59E+08 - - - 2.39 0.9967 221125_WJC_METTL3_EV_vs_WT_F07.05277.05277.2 0.0012 18-Aug R.MSELSSSRPK.R "sp|Q14527|HLTF_HUMAN,tr|A0A0C4DGA6|A0A0C4DGA6_HUMAN" 2 1120.5547 0.8 94271 5277 2 1120.550867 561.2846 Helicase-like transcription factor OS=Homo sapiens OX=9606 GN=HLTF PE=1 SV=2 8.5 1490.9 - 1.75E+06 - - - -3.3831 - 1.822 0.298 - 192 1 2 0 -0.0038 10 0 0 0 4.21E+07 5.30E+07 - - - 2.9154 0.9996 221125_WJC_METTL3_EV_vs_WT_F07.05285.05285.2 0.0185 14-Oct K.TDSEKPFR.G "sp|Q9Y2W1|TR150_HUMAN,tr|A0A3B3ITZ9|A0A3B3ITZ9_HUMAN" 2 978.4771 2.45 94277 5285 2 978.476378 490.2458 Thyroid hormone receptor-associated protein 3 OS=Homo sapiens OX=9606 GN=THRAP3 PE=1 SV=2 5.74 1491.8 - 1.24E+07 - - - -0.697 - 1.814 0.357 - 419.9 1 2 0 -0.0007 8 0 0 0 6.74E+09 2.75E+09 - - - 3.4737 0.9999 221125_WJC_METTL3_EV_vs_WT_F07.05287.05287.2 4.80E-05 16-Sep R.QSQADYETR[166.11].A "sp|Q9NP61|ARFG3_HUMAN,tr|H0Y6A0|H0Y6A0_HUMAN" 2 1106.4868 1.5 94279 5287 2 1106.486134 554.2507 ADP-ribosylation factor GTPase-activating protein 3 OS=Homo sapiens OX=9606 GN=ARFGAP3 PE=1 SV=1 4.37 1491.9 - 6.95E+06 - - - -0.5893 - 2.126 0.481 - 468.2 1 2 0 -0.0007 9 0 0 0 3.01E+08 2.01E+08 - - - 4.7755 0.9126 221125_WJC_METTL3_EV_vs_WT_F07.05289.05289.2 0.301 18-Aug R.NMSQEQVAQK[136.11].L "sp|Q5JPH6|SYEM_HUMAN,tr|H3BTB7|H3BTB7_HUMAN" 2 1169.559 0.46 94281 5289 2 1169.563549 585.7868 "Probable glutamate--tRNA ligase, mitochondrial OS=Homo sapiens OX=9606 GN=EARS2 PE=1 SV=2" 6 1492 - 3.28E+06 - - - 3.8707 - 1.097 0.171 - 139.9 1 2 0 0.0045 10 0 0 0 1.69E+07 3.66E+07 - - - 0.561 0.9893 221125_WJC_METTL3_EV_vs_WT_F07.05291.05291.2 0.00831 13/16 Q.KGELTGEVR.M "sp|Q14315|FLNC_HUMAN,sp|P21333|FLNA_HUMAN,tr|Q60FE5|Q60FE5_HUMAN,tr|H0Y5F3|H0Y5F3_HUMAN" 4 987.5349 0.99 94283 5291 2 987.534102 494.7747 Filamin-C OS=Homo sapiens OX=9606 GN=FLNC PE=1 SV=3 6.14 1492.2 - 2.16E+06 - - - -0.8172 - 2.441 0.375 - 600 1 1 0 -0.0008 9 0 0 0 4.04E+07 4.07E+07 - - - 4.3923 1 221125_WJC_METTL3_EV_vs_WT_F07.05293.05293.2 4.93E-06 15/24 K.EATAGNPGGQTVR[166.11].E "sp|P27708|PYR1_HUMAN,tr|F8VPD4|F8VPD4_HUMAN" 2 1266.6192 0.57 94285 5293 2 1266.619151 634.3169 CAD protein OS=Homo sapiens OX=9606 GN=CAD PE=1 SV=3 6.1 1492.4 - 1.63E+06 - - - -0.0371 - 2.417 0.609 - 538.7 1 2 0 0 13 0 0 0 3.24E+07 5.72E+07 - - - 5.8041 0.9998 221125_WJC_METTL3_EV_vs_WT_F07.05300.05300.2 0.000102 16-Nov R.QSQADYETR.A "sp|Q9NP61|ARFG3_HUMAN,tr|H0Y6A0|H0Y6A0_HUMAN" 2 1096.4785 1.53 94290 5300 2 1096.476472 549.2465 ADP-ribosylation factor GTPase-activating protein 3 OS=Homo sapiens OX=9606 GN=ARFGAP3 PE=1 SV=1 4.37 1493.1 - 2.25E+07 - - - -1.8641 - 2.048 0.593 - 753.3 1 2 0 -0.002 9 0 0 0 3.08E+08 2.01E+08 - - - 5.4942 0.9997 221125_WJC_METTL3_EV_vs_WT_F07.05301.05301.2 0.00127 14-Sep K.TDSEK[136.11]PFR[166.11].G "sp|Q9Y2W1|TR150_HUMAN,tr|A0A3B3ITZ9|A0A3B3ITZ9_HUMAN" 2 996.4995 2.45 94291 5301 2 996.498442 499.257 Thyroid hormone receptor-associated protein 3 OS=Homo sapiens OX=9606 GN=THRAP3 PE=1 SV=2 5.74 1493.1 - 1.45E+07 - - - -1.0918 - 2.034 0.388 - 466.4 1 2 0 -0.0011 8 0 0 0 6.75E+09 2.75E+09 - - - 4.0478 0.9856 221125_WJC_METTL3_EV_vs_WT_F07.05303.05303.2 0.00869 16-Dec Q.K[136.11]GELTGEVR[166.11].M "sp|Q14315|FLNC_HUMAN,sp|P21333|FLNA_HUMAN,tr|Q60FE5|Q60FE5_HUMAN,tr|H0Y5F3|H0Y5F3_HUMAN" 4 1005.5574 0.99 94293 5303 2 1005.55592 503.786 Filamin-C OS=Homo sapiens OX=9606 GN=FLNC PE=1 SV=3 6.14 1493.2 - 4.49E+06 - - - -1.4509 - 2.359 0.388 - 494.8 1 1 0 -0.0015 9 0 0 0 4.04E+07 4.07E+07 - - - 4.3892 0.9999 221125_WJC_METTL3_EV_vs_WT_F07.05304.05304.2 9.43E-05 18-Dec K.AYSEAHEISK.E sp|P61981|1433G_HUMAN 1 1133.5353 1.42 94294 5304 2 1133.534422 567.7749 14-3-3 protein gamma OS=Homo sapiens OX=9606 GN=YWHAG PE=1 SV=2 5.4 1493.3 - 4.42E+06 - - - -0.7772 - 1.921 0.514 - 392.3 1 2 0 -0.0009 10 0 0 0 4.49E+07 3.16E+07 - - - 4.6594 0.9839 221125_WJC_METTL3_EV_vs_WT_F07.05309.05309.2 6.55E-05 16-Sep V.KAPGFGDNR.K "sp|P10809|CH60_HUMAN,tr|A0A7I2V2X6|A0A7I2V2X6_HUMAN,tr|A0A7I2YQK6|A0A7I2YQK6_HUMAN,tr|A0A7I2V599|A0A7I2V599_HUMAN,tr|A0A7I2V5M1|A0A7I2V5M1_HUMAN" 5 960.4777 4.23 94297 5309 2 960.476513 481.2461 "60 kDa heat shock protein, mitochondrial OS=Homo sapiens OX=9606 GN=HSPD1 PE=1 SV=2" 8.75 1493.9 - 5.93E+06 - - - -1.265 - 1.85 0.441 - 291.2 1 1 0 -0.0012 9 0 0 0 2.03E+08 4.79E+07 - - - 4.0776 0.9994 221125_WJC_METTL3_EV_vs_WT_F07.05310.05310.2 0.000911 12-Oct R.HNLSLNK.C "sp|Q96NZ1|FOXN4_HUMAN,sp|O00409|FOXN3_HUMAN,sp|Q9UPW0|FOXJ3_HUMAN,sp|P55316|FOXG1_HUMAN,sp|P32314|FOXN2_HUMAN,sp|Q92949|FOXJ1_HUMAN,sp|O15353|FOXN1_HUMAN,sp|Q9P0K8|FOXJ2_HUMAN,tr|H0YJ54|H0YJ54_HUMAN,tr|H0YJ22|H0YJ22_HUMAN,tr|C9JTA7|C9JTA7_HUMAN,tr|H7C1Y6|H7C1Y6_HUMAN,tr|H0YJ94|H0YJ94_HUMAN,tr|A0A087X1X6|A0A087X1X6_HUMAN,tr|C9JVP0|C9JVP0_HUMAN,tr|H0YJG3|H0YJG3_HUMAN,tr|G3V3A7|G3V3A7_HUMAN,tr|S4R3U5|S4R3U5_HUMAN" 18 824.4505 0.74 94298 5310 2 824.451541 413.2325 Forkhead box protein N4 OS=Homo sapiens OX=9606 GN=FOXN4 PE=1 SV=2 8.76 1494 - 7.00E+06 - - - 1.3221 - 1.848 0.316 - 347.4 1 2 0 0.0011 7 0 0 0 7.56E+07 1.03E+08 - - - 3.3205 0.9944 221125_WJC_METTL3_EV_vs_WT_F07.05311.05311.2 2.30E-06 16-Oct A.GPDEDLSHR.N "sp|Q9HC07|TM165_HUMAN,tr|D6RBL0|D6RBL0_HUMAN,tr|D6RD79|D6RD79_HUMAN" 3 1024.4574 1.11 94299 5311 2 1024.457046 513.236 Transmembrane protein 165 OS=Homo sapiens OX=9606 GN=TMEM165 PE=1 SV=1 4.54 1494 - 6.30E+06 - - - -0.3329 - 2.086 0.567 - 533.4 1 1 0 -0.0003 9 0 0 0 7.48E+07 6.72E+07 - - - 5.3559 0.9558 221125_WJC_METTL3_EV_vs_WT_F07.05312.05312.2 6.06E-05 16-Oct A.GPDEDLSHR[166.11].N "sp|Q9HC07|TM165_HUMAN,tr|D6RBL0|D6RBL0_HUMAN,tr|D6RD79|D6RD79_HUMAN" 3 1034.4657 1.59 94300 5312 2 1034.462503 518.2401 Transmembrane protein 165 OS=Homo sapiens OX=9606 GN=TMEM165 PE=1 SV=1 4.54 1494 - 5.10E+06 - - - -3.0489 - 2.05 0.437 - 515 1 1 0 -0.0032 9 0 0 0 7.48E+07 4.72E+07 - - - 4.3444 0.9837 221125_WJC_METTL3_EV_vs_WT_F07.05318.05318.2 1.1 20-Sep K.VSQNSQLANEK[136.11].L "sp|Q13464|ROCK1_HUMAN,tr|A0A0U1RQV4|A0A0U1RQV4_HUMAN" 2 1224.619 4.89 94304 5318 2 1224.619259 613.3168 Rho-associated protein kinase 1 OS=Homo sapiens OX=9606 GN=ROCK1 PE=1 SV=1 5.97 1494.6 - 967869 - - - 0.2278 - 1.24 0.093 - 123.2 1 2 0 0.0003 11 0 0 0 2.62E+07 5.37E+06 - - - 0.3097 0.9999 221125_WJC_METTL3_EV_vs_WT_F07.05321.05321.3 3.10E-05 14/36 K.VSRPENEQLR.N "sp|Q8ND56|LS14A_HUMAN,tr|A0A140TA76|A0A140TA76_HUMAN,tr|K7EMZ9|K7EMZ9_HUMAN" 3 1226.6367 1 94305 5321 3 1226.635152 409.8862 Protein LSM14 homolog A OS=Homo sapiens OX=9606 GN=LSM14A PE=1 SV=3 6.11 1495 - 1.04E+07 - - - -1.3011 - 2.377 0.443 - 335.5 1 2 0 -0.0016 10 0 0 0 2.22E+10 2.22E+10 - - - 6.0072 1 221125_WJC_METTL3_EV_vs_WT_F07.05322.05322.2 1.07E-05 18-Oct K.GAVEC[160.03]C[160.03]PNC[160.03]R[166.11].G sp|P31689|DNJA1_HUMAN 1 1231.4772 0.46 94306 5322 2 1231.476455 616.7459 DnaJ homolog subfamily A member 1 OS=Homo sapiens OX=9606 GN=DNAJA1 PE=1 SV=2 5.98 1495.1 - 7.22E+06 - - - -0.5782 - 2.203 0.63 - 487.1 1 2 0 -0.0007 10 0 0 0 7.78E+07 1.67E+08 - - - 5.8986 0.9999 221125_WJC_METTL3_EV_vs_WT_F07.05323.05323.3 0.000123 13/36 K.VSR[166.11]PENEQLR[166.11].N "sp|Q8ND56|LS14A_HUMAN,tr|A0A140TA76|A0A140TA76_HUMAN,tr|K7EMZ9|K7EMZ9_HUMAN" 3 1246.6533 1 94307 5323 3 1246.651834 416.5584 Protein LSM14 homolog A OS=Homo sapiens OX=9606 GN=LSM14A PE=1 SV=3 6.11 1495.1 - 1.25E+07 - - - -1.1663 - 2.052 0.409 - 151.3 1 2 0 -0.0015 10 0 0 0 2.22E+10 2.22E+10 - - - 5.1988 0.9994 221125_WJC_METTL3_EV_vs_WT_F07.05324.05324.2 0.0365 16-Aug K.ETQTDSISR[166.11].Y "sp|O14974|MYPT1_HUMAN,tr|H0YIM2|H0YIM2_HUMAN,tr|H0YIS3|H0YIS3_HUMAN" 3 1045.4915 0.19 94308 5324 2 1045.491396 523.753 Protein phosphatase 1 regulatory subunit 12A OS=Homo sapiens OX=9606 GN=PPP1R12A PE=1 SV=1 4.37 1495.1 - 3.69E+06 - - - -0.1349 - 1.746 0.303 - 385.2 1 2 0 -0.0001 9 0 0 0 1.95E+07 1.02E+08 - - - 2.8913 1 221125_WJC_METTL3_EV_vs_WT_F07.05325.05325.2 1.45E-06 18-Dec K.GAVEC[160.03]C[160.03]PNC[160.03]R.G sp|P31689|DNJA1_HUMAN 1 1221.4689 0.46 94309 5325 2 1221.46764 611.7417 DnaJ homolog subfamily A member 1 OS=Homo sapiens OX=9606 GN=DNAJA1 PE=1 SV=2 5.98 1495.3 - 2.96E+06 - - - -1.0291 - 2.195 0.62 - 705.9 1 2 0 -0.0013 10 0 0 0 7.78E+07 1.67E+08 - - - 5.8144 0.9418 221125_WJC_METTL3_EV_vs_WT_F07.05326.05326.3 999 28-Feb F.C[160.03]EMC[160.03]C[160.03]DC[160.03]R.M sp|Q8TF05|PP4R1_HUMAN 1 1189.3443 43.28 94310 5326 3 1189.342046 397.4554 Serine\threonine-protein phosphatase 4 regulatory subunit 1 OS=Homo sapiens OX=9606 GN=PPP4R1 PE=1 SV=1 4.37 1495.3 - 1.85E+06 - - - -1.8876 - 0.327 0.812 - 7.6 1 1 0 -0.0022 8 0 0 0 2.05E+07 4.73E+05 - - - 4.0987 0.9999 221125_WJC_METTL3_EV_vs_WT_F07.05327.05327.2 5.01E-07 18-Oct K.FQNNSEDNVK.K "sp|Q8IWJ2|GCC2_HUMAN,tr|B8ZZA5|B8ZZA5_HUMAN,tr|B8ZZW2|B8ZZW2_HUMAN" 3 1193.5313 2.23 94311 5327 2 1193.53076 597.7729 GRIP and coiled-coil domain-containing protein 2 OS=Homo sapiens OX=9606 GN=GCC2 PE=1 SV=4 4.37 1495.4 - 1.70E+06 - - - -0.4357 - 1.968 0.568 - 225.3 1 2 0 -0.0005 10 0 0 0 1.51E+07 6.77E+06 - - - 5.1258 0.9997 221125_WJC_METTL3_EV_vs_WT_F07.05328.05328.2 0.0101 13/18 K.VSR[166.11]PENEQLR[166.11].N "sp|Q8ND56|LS14A_HUMAN,tr|A0A140TA76|A0A140TA76_HUMAN,tr|K7EMZ9|K7EMZ9_HUMAN" 3 1246.6533 1.02 94312 5328 2 1246.651282 624.3339 Protein LSM14 homolog A OS=Homo sapiens OX=9606 GN=LSM14A PE=1 SV=3 6.11 1495.6 - 1.47E+06 - - - -1.6091 - 2.104 0.414 - 322.9 1 2 0 -0.002 10 0 0 0 3.59E+09 3.53E+09 - - - 4.1745 0.9991 221125_WJC_METTL3_EV_vs_WT_F07.05337.05337.2 0.266 16-Sep R.RGGADVNIR.H sp|P08621|RU17_HUMAN 1 956.5152 1.39 94319 5337 2 956.515231 479.2649 U1 small nuclear ribonucleoprotein 70 kDa OS=Homo sapiens OX=9606 GN=SNRNP70 PE=1 SV=2 9.6 1496.4 - 2.54E+06 - - - 0.0565 - 1.814 0.226 - 176.2 1 2 0 0.0001 9 0 0 0 4.06E+07 2.91E+07 - - - 2.4331 0.7775 221125_WJC_METTL3_EV_vs_WT_F07.05338.05338.2 0.000131 13/16 V.SR[166.11]PENEQLR[166.11].N "sp|Q8ND56|LS14A_HUMAN,tr|A0A140TA76|A0A140TA76_HUMAN,tr|K7EMZ9|K7EMZ9_HUMAN" 3 1147.5849 1.14 94320 5338 2 1147.590158 574.7997 Protein LSM14 homolog A OS=Homo sapiens OX=9606 GN=LSM14A PE=1 SV=3 5.86 1496.4 - 2.36E+06 - - - 4.6045 - 1.959 0.341 - 392.5 1 1 0 0.0053 9 0 0 0 1.62E+09 1.42E+09 - - - 3.5034 0.9992 221125_WJC_METTL3_EV_vs_WT_F07.05340.05340.2 0.00705 14-Aug K.SDEGHPFR.A "sp|Q9NQC3|RTN4_HUMAN,tr|A0A0U1RQR6|A0A0U1RQR6_HUMAN,tr|F8W914|F8W914_HUMAN,tr|H7C106|H7C106_HUMAN" 4 943.4148 1.17 94322 5340 2 943.414484 472.7147 Reticulon-4 OS=Homo sapiens OX=9606 GN=RTN4 PE=1 SV=2 5.3 1496.6 - 1.34E+06 - - - -0.3286 - 1.675 0.269 - 227.6 1 2 0 -0.0003 8 0 0 0 4.24E+07 3.62E+07 - - - 2.5834 0.9911 221125_WJC_METTL3_EV_vs_WT_F07.05343.05343.2 0.0833 16-Aug K.ITITNDK[136.11]GR[166.11].L "sp|P54652|HSP72_HUMAN,sp|P0DMV8|HS71A_HUMAN,sp|P34931|HS71L_HUMAN,sp|P11142|HSP7C_HUMAN,sp|P0DMV9|HS71B_HUMAN,sp|P17066|HSP76_HUMAN,tr|E9PNE6|E9PNE6_HUMAN,tr|A8K7Q2|A8K7Q2_HUMAN,tr|E9PKE3|E9PKE3_HUMAN,tr|E9PM13|E9PM13_HUMAN,tr|E9PS65|E9PS65_HUMAN,tr|Q53FA3|Q53FA3_HUMAN,tr|V9GZ37|V9GZ37_HUMAN,tr|A0A0G2JIW1|A0A0G2JIW1_HUMAN" 14 1034.5839 0.15 94323 5343 2 1034.583471 518.2992 Heat shock-related 70 kDa protein 2 OS=Homo sapiens OX=9606 GN=HSPA2 PE=1 SV=1 8.75 1496.9 - 8.21E+06 - - - -0.4417 - 1.614 0.293 - 236.6 1 2 1 -0.0005 9 0 0 0 3.93E+08 2.68E+09 - - - 2.5899 1 221125_WJC_METTL3_EV_vs_WT_F07.05345.05345.3 7.84E-05 14/40 K.AEGYEVAHGGR[166.11].C "sp|P53041|PPP5_HUMAN,tr|H0YDU8|H0YDU8_HUMAN,tr|A8MU39|A8MU39_HUMAN" 3 1154.5344 0.48 94325 5345 3 1154.533563 385.8521 Serine\threonine-protein phosphatase 5 OS=Homo sapiens OX=9606 GN=PPP5C PE=1 SV=1 5.4 1497 - 2.96E+06 - - - -0.7293 - 2.505 0.459 - 392.5 1 2 0 -0.0008 11 0 0 0 3.16E+07 6.53E+07 - - - 6.2659 0.9915 221125_WJC_METTL3_EV_vs_WT_F07.05351.05351.2 4.78E-05 16-Dec V.SRPENEQLR.N "sp|Q8ND56|LS14A_HUMAN,tr|A0A140TA76|A0A140TA76_HUMAN,tr|K7EMZ9|K7EMZ9_HUMAN" 3 1127.5683 1.14 94329 5351 2 1127.567806 564.7914 Protein LSM14 homolog A OS=Homo sapiens OX=9606 GN=LSM14A PE=1 SV=3 5.86 1497.7 - 1.09E+07 - - - -0.4683 - 2.071 0.468 - 301.3 1 1 0 -0.0005 9 0 0 0 1.62E+09 1.42E+09 - - - 4.6037 0.9953 221125_WJC_METTL3_EV_vs_WT_F07.05355.05355.2 0.00673 16-Aug K.ITITNDKGR.L "sp|P54652|HSP72_HUMAN,sp|P0DMV8|HS71A_HUMAN,sp|P34931|HS71L_HUMAN,sp|P11142|HSP7C_HUMAN,sp|P0DMV9|HS71B_HUMAN,sp|P17066|HSP76_HUMAN,tr|E9PNE6|E9PNE6_HUMAN,tr|A8K7Q2|A8K7Q2_HUMAN,tr|E9PKE3|E9PKE3_HUMAN,tr|E9PM13|E9PM13_HUMAN,tr|E9PS65|E9PS65_HUMAN,tr|Q53FA3|Q53FA3_HUMAN,tr|V9GZ37|V9GZ37_HUMAN,tr|A0A0G2JIW1|A0A0G2JIW1_HUMAN" 14 1016.5615 0.15 94333 5355 2 1016.560967 509.288 Heat shock-related 70 kDa protein 2 OS=Homo sapiens OX=9606 GN=HSPA2 PE=1 SV=1 8.75 1497.9 - 2.02E+06 - - - -0.483 - 1.794 0.337 - 233.4 1 2 1 -0.0005 9 0 0 0 3.93E+08 2.68E+09 - - - 3.2208 0.819 221125_WJC_METTL3_EV_vs_WT_F07.05357.05357.2 1.05 20-May P.NAIQVC[160.03]TDSEK.H "sp|Q3KR37|ASTRB_HUMAN,tr|A0A1B0GUD6|A0A1B0GUD6_HUMAN,tr|A0A1B0GWG7|A0A1B0GWG7_HUMAN,tr|E9PRD6|E9PRD6_HUMAN,tr|A0A0J9YXF6|A0A0J9YXF6_HUMAN,tr|A0A024R3M2|A0A024R3M2_HUMAN,tr|J3KNL5|J3KNL5_HUMAN,tr|A0A2R8Y5X2|A0A2R8Y5X2_HUMAN" 8 1263.5765 2.2 94335 5357 2 1263.575914 632.7955 Protein Aster-B OS=Homo sapiens OX=9606 GN=GRAMD1B PE=1 SV=1 4.37 1498.2 - 1.17E+06 - - - -0.4764 - 1.368 0.226 - 64.9 3 1 0 -0.0006 11 0 0 0 8.59E+06 3.90E+06 - - - 1.3446 0.9893 221125_WJC_METTL3_EV_vs_WT_F07.05362.05362.3 0.536 Dec-36 K.VSR[166.11]PENEQLR.N "sp|Q8ND56|LS14A_HUMAN,tr|A0A140TA76|A0A140TA76_HUMAN,tr|K7EMZ9|K7EMZ9_HUMAN" 3 1236.645 - 94338 5362 3 1236.644381 413.2223 Protein LSM14 homolog A OS=Homo sapiens OX=9606 GN=LSM14A PE=1 SV=3 6.11 1498.7 - 7.69E+06 - - - -0.5151 - 1.984 0.11 - 192.6 1 2 0 -0.0006 10 0 0 0 - - - - - 1.7671 0.9988 221125_WJC_METTL3_EV_vs_WT_F07.05384.05384.2 0.0144 18-Oct R.EGQEDQGLTK.D "sp|O95758|PTBP3_HUMAN,sp|P26599|PTBP1_HUMAN,tr|A0A0U1RRM4|A0A0U1RRM4_HUMAN,tr|A6NLN1|A6NLN1_HUMAN,tr|A0A0D9SF20|A0A0D9SF20_HUMAN,tr|A0A7I2V621|A0A7I2V621_HUMAN,tr|A0A087WUW5|A0A087WUW5_HUMAN" 7 1103.5095 6.69 94354 5384 2 1103.506911 552.762 Polypyrimidine tract-binding protein 3 OS=Homo sapiens OX=9606 GN=PTBP3 PE=1 SV=2 4.14 1500.9 - 6.42E+06 - - - -2.3298 - 1.697 0.353 - 503.9 1 2 0 -0.0026 10 0 0 0 2.12E+09 3.18E+08 - - - 3.1237 0.9974 221125_WJC_METTL3_EV_vs_WT_F07.05387.05387.2 0.0715 18-Nov K.VSRPENEQLR[166.11].N "sp|Q8ND56|LS14A_HUMAN,tr|A0A140TA76|A0A140TA76_HUMAN,tr|K7EMZ9|K7EMZ9_HUMAN" 3 1236.645 - 94357 5387 2 1236.642079 619.3298 Protein LSM14 homolog A OS=Homo sapiens OX=9606 GN=LSM14A PE=1 SV=3 6.11 1501.2 - 2.62E+06 - - - -2.3766 - 1.737 0.269 - 149 2 2 0 -0.0029 10 0 0 0 - - - - - 2.4337 0.9654 221125_WJC_METTL3_EV_vs_WT_F07.05388.05388.2 0.301 16-Aug K.ITITNDKGR[166.11].L "sp|P54652|HSP72_HUMAN,sp|P0DMV8|HS71A_HUMAN,sp|P34931|HS71L_HUMAN,sp|P11142|HSP7C_HUMAN,sp|P0DMV9|HS71B_HUMAN,sp|P17066|HSP76_HUMAN,tr|E9PNE6|E9PNE6_HUMAN,tr|A8K7Q2|A8K7Q2_HUMAN,tr|E9PKE3|E9PKE3_HUMAN,tr|E9PM13|E9PM13_HUMAN,tr|E9PS65|E9PS65_HUMAN,tr|Q53FA3|Q53FA3_HUMAN,tr|V9GZ37|V9GZ37_HUMAN,tr|A0A0G2JIW1|A0A0G2JIW1_HUMAN" 14 1026.5697 - 94358 5388 2 1026.568409 514.2921 Heat shock-related 70 kDa protein 2 OS=Homo sapiens OX=9606 GN=HSPA2 PE=1 SV=1 8.75 1501.4 - 2.34E+06 - - - -1.2849 - 1.538 0.188 - 153.1 1 2 1 -0.0013 9 0 0 0 - - - - - 1.6746 0.9864 221125_WJC_METTL3_EV_vs_WT_F07.05391.05391.2 0.00109 13/14 S.RPENEQLR.N "sp|Q8ND56|LS14A_HUMAN,tr|A0A140TA76|A0A140TA76_HUMAN,tr|K7EMZ9|K7EMZ9_HUMAN" 3 1040.5363 1.07 94359 5391 2 1040.534301 521.2754 Protein LSM14 homolog A OS=Homo sapiens OX=9606 GN=LSM14A PE=1 SV=3 6.14 1501.7 - 6.14E+06 - - - -1.9269 - 2.444 0.442 - 413 1 1 0 -0.002 8 0 0 0 1.04E+08 9.69E+07 - - - 5.0001 0.998 221125_WJC_METTL3_EV_vs_WT_F07.05393.05393.2 0.00052 14-Oct K.SQDSLPQK[136.11].N sp|Q16706|MA2A1_HUMAN 1 909.4647 0.96 94360 5393 2 909.461671 455.7396 Alpha-mannosidase 2 OS=Homo sapiens OX=9606 GN=MAN2A1 PE=1 SV=2 5.55 1501.9 - 2.64E+06 - - - -3.3426 - 1.773 0.354 - 440.9 1 2 0 -0.003 8 0 0 0 5.76E+07 5.98E+07 - - - 3.3818 0.9997 221125_WJC_METTL3_EV_vs_WT_F07.05395.05395.2 0.00077 20-Nov R.DSGTLQSQEAK.A "sp|Q641Q2|WAC2A_HUMAN,sp|Q9Y4E1|WAC2C_HUMAN,tr|F8W7U3|F8W7U3_HUMAN,tr|J3KP36|J3KP36_HUMAN,tr|E7ESD2|E7ESD2_HUMAN,tr|A0A0A0MR88|A0A0A0MR88_HUMAN,tr|A0A087WYF6|A0A087WYF6_HUMAN,tr|A0A096LPC5|A0A096LPC5_HUMAN" 8 1162.5466 1 94361 5395 2 1162.547676 582.2806 WASH complex subunit 2A OS=Homo sapiens OX=9606 GN=WASHC2A PE=1 SV=3 4.37 1502.2 - 2.15E+06 - - - 0.929 - 2.026 0.384 - 297.8 1 2 0 0.0011 11 0 0 0 1.14E+07 1.14E+07 - - - 3.787 0.9971 221125_WJC_METTL3_EV_vs_WT_F07.05400.05400.3 0.024 Sep-36 K.EISAHNQQLR.E "sp|Q8TEK3|DOT1L_HUMAN,tr|V9GY76|V9GY76_HUMAN" 2 1194.6105 0.41 94365 5400 3 1194.610504 399.2108 "Histone-lysine N-methyltransferase, H3 lysine-79 specific OS=Homo sapiens OX=9606 GN=DOT1L PE=1 SV=3" 6.85 1502.6 - 3.03E+06 - - - -0.0251 - 1.698 0.224 - 91.2 1 2 0 0 10 0 0 0 2.99E+07 7.37E+07 - - - 2.5836 0.9919 221125_WJC_METTL3_EV_vs_WT_F07.05404.05404.2 0.0515 18-Nov K.SSTPSSISEK.S sp|Q63HK5|TSH3_HUMAN 1 1021.4928 2.5 94367 5404 2 1021.489309 511.7537 Teashirt homolog 3 OS=Homo sapiens OX=9606 GN=TSHZ3 PE=1 SV=2 5.72 1503.1 - 2.56E+06 - - - -3.3872 - 1.643 0.227 - 303 1 2 0 -0.0035 10 0 0 0 4.32E+07 1.73E+07 - - - 2.1025 0.9868 221125_WJC_METTL3_EV_vs_WT_F07.05411.05411.2 0.000521 14-Sep K.SQDSLPQK.N sp|Q16706|MA2A1_HUMAN 1 901.4505 0.91 94372 5411 2 901.446621 451.7325 Alpha-mannosidase 2 OS=Homo sapiens OX=9606 GN=MAN2A1 PE=1 SV=2 5.55 1503.9 - 6.18E+06 - - - -4.3153 - 1.632 0.236 - 366.2 1 2 0 -0.0039 8 0 0 0 5.39E+07 5.95E+07 - - - 2.2601 0.9997 221125_WJC_METTL3_EV_vs_WT_F07.05413.05413.2 0.0123 14/18 R.R[166.11]DDGLSAAAR[166.11].K "sp|P84101|SERF2_HUMAN,tr|B8ZZY7|B8ZZY7_HUMAN,tr|F8WBV6|F8WBV6_HUMAN,tr|F8WBN3|F8WBN3_HUMAN,tr|B9A031|B9A031_HUMAN,tr|C9JQZ0|C9JQZ0_HUMAN" 6 1050.5321 0.72 94374 5413 2 1050.531536 526.2733 Small EDRK-rich factor 2 OS=Homo sapiens OX=9606 GN=SERF2 PE=1 SV=1 5.96 1504.1 - 2.76E+06 - - - -0.5473 - 2.394 0.303 - 393.2 1 2 0 -0.0006 10 0 0 0 3.10E+07 4.30E+07 - - - 3.7155 0.9986 221125_WJC_METTL3_EV_vs_WT_F07.05414.05414.2 0.0458 14-Oct K.KTDFVNSR.T sp|Q99959|PKP2_HUMAN 1 965.493 0.83 94375 5414 2 965.490183 483.7538 Plakophilin-2 OS=Homo sapiens OX=9606 GN=PKP2 PE=1 SV=2 8.75 1504.2 - 2.31E+06 - - - -2.9633 - 1.898 0.338 - 298.2 1 2 0 -0.0029 8 0 0 0 4.06E+07 4.86E+07 - - - 3.4692 0.9997 221125_WJC_METTL3_EV_vs_WT_F07.05415.05415.2 2.18E-05 18-Nov K.DAYC[160.03]C[160.03]AQQGK.R sp|Q9NR33|DPOE4_HUMAN 1 1199.4699 1.23 94376 5415 2 1199.466831 600.7422 DNA polymerase epsilon subunit 4 OS=Homo sapiens OX=9606 GN=POLE4 PE=1 SV=2 5.82 1504.3 - 1.64E+06 - - - -2.5945 - 2.047 0.592 - 325 1 2 0 -0.0031 10 0 0 0 8.36E+07 6.80E+07 - - - 5.4122 0.9805 221125_WJC_METTL3_EV_vs_WT_F07.05416.05416.2 0.0977 16-Jul K.DQLSEQTQK.Y "sp|Q9BZF9|UACA_HUMAN,tr|H0YNH8|H0YNH8_HUMAN,tr|F5H2B9|F5H2B9_HUMAN" 3 1075.5146 0.14 94377 5416 2 1075.511986 538.7646 Uveal autoantigen with coiled-coil domains and ankyrin repeats OS=Homo sapiens OX=9606 GN=UACA PE=1 SV=2 4.37 1504.5 - 881991 - - - -2.4007 - 1.29 0.149 - 170 1 2 0 -0.0026 9 0 0 0 9.24E+06 6.83E+07 - - - 0.8774 1 221125_WJC_METTL3_EV_vs_WT_F07.05420.05420.2 3.78E-08 18-Oct K.DAYC[160.03]C[160.03]AQQGK[136.11].R sp|Q9NR33|DPOE4_HUMAN 1 1207.4841 1.22 94379 5420 2 1207.482129 604.7493 DNA polymerase epsilon subunit 4 OS=Homo sapiens OX=9606 GN=POLE4 PE=1 SV=2 5.82 1504.9 - 3.81E+06 - - - -1.6679 - 2.057 0.645 - 258.2 1 2 0 -0.002 10 0 0 0 8.17E+07 6.67E+07 - - - 5.8176 0.9996 221125_WJC_METTL3_EV_vs_WT_F07.05427.05427.2 6.07E-05 20-Oct R.GPPPSYGGSSR.Y "sp|Q96E39|RMXL1_HUMAN,sp|P38159|RBMX_HUMAN,tr|H3BUY5|H3BUY5_HUMAN" 3 1060.4938 1.57 94384 5427 2 1060.492287 531.2542 "RNA binding motif protein, X-linked-like-1 OS=Homo sapiens OX=9606 GN=RBMXL1 PE=1 SV=1" 8.75 1505.7 - 2.20E+06 - - - -1.4003 - 1.678 0.453 - 273.3 1 2 0 -0.0015 11 0 0 0 1.33E+08 8.46E+07 - - - 3.7866 0.965 221125_WJC_METTL3_EV_vs_WT_F07.05429.05429.2 0.0015 14-Sep L.QVQHPAAK[136.11].S "sp|P49368|TCPG_HUMAN,tr|E9PM09|E9PM09_HUMAN,tr|Q5SZW8|Q5SZW8_HUMAN,tr|E9PRC8|E9PRC8_HUMAN,tr|B4DUR8|B4DUR8_HUMAN,tr|Q5SZX9|Q5SZX9_HUMAN,tr|Q5SZX6|Q5SZX6_HUMAN" 7 885.4912 0.03 94386 5429 2 885.489581 443.7529 T-complex protein 1 subunit gamma OS=Homo sapiens OX=9606 GN=CCT3 PE=1 SV=4 8.76 1505.8 - 2.53E+06 - - - -1.8284 - 1.733 0.382 - 440.7 1 1 0 -0.0016 8 0 0 0 6.94E+06 2.01E+08 - - - 3.5203 0.9874 221125_WJC_METTL3_EV_vs_WT_F07.05430.05430.3 0.000391 Dec-40 N.AAHVEYSTAAR[166.11].H sp|P49411|EFTU_HUMAN 1 1184.5814 1.49 94387 5430 3 1184.580029 395.8677 "Elongation factor Tu, mitochondrial OS=Homo sapiens OX=9606 GN=TUFM PE=1 SV=2" 6.79 1505.9 - 2.15E+06 - - - -1.1194 - 2.209 0.383 - 219.9 1 1 0 -0.0013 11 0 0 0 1.18E+08 7.91E+07 - - - 5.0612 0.9997 221125_WJC_METTL3_EV_vs_WT_F07.05431.05431.2 0.00632 20-Oct R.QLEDGDQPESK[136.11].K "sp|Q92945|FUBP2_HUMAN,tr|M0R0I5|M0R0I5_HUMAN,tr|M0R0C6|M0R0C6_HUMAN,tr|A0A087WTP3|A0A087WTP3_HUMAN" 4 1252.5663 1.54 94388 5431 2 1252.567415 627.2904 Far upstream element-binding protein 2 OS=Homo sapiens OX=9606 GN=KHSRP PE=1 SV=4 3.92 1506 - 2.05E+06 - - - 0.9101 - 2.004 0.414 - 398.5 1 2 0 0.0011 11 0 0 0 1.98E+08 1.29E+08 - - - 3.979 0.9997 221125_WJC_METTL3_EV_vs_WT_F07.05432.05432.2 9.72E-08 24-Dec K.AQPAQPADEPAEK[136.11].A "sp|P25786|PSA1_HUMAN,tr|F5GX11|F5GX11_HUMAN" 2 1358.6558 1.48 94389 5432 2 1358.652171 680.3352 Proteasome subunit alpha type-1 OS=Homo sapiens OX=9606 GN=PSMA1 PE=1 SV=1 4.14 1506.1 - 821957 - - - -2.6408 - 2.043 0.61 - 454.4 1 2 0 -0.0036 13 0 0 0 2.56E+07 1.73E+07 - - - 5.3789 0.995 221125_WJC_METTL3_EV_vs_WT_F07.05436.05436.2 0.448 18-Aug R.EIQVQHPAAK[136.11].S "sp|P49368|TCPG_HUMAN,tr|E9PRC8|E9PRC8_HUMAN,tr|B4DUR8|B4DUR8_HUMAN,tr|Q5SZX9|Q5SZX9_HUMAN,tr|Q5SZX6|Q5SZX6_HUMAN" 5 1127.6179 0.5 94391 5436 2 1127.616924 564.8162 T-complex protein 1 subunit gamma OS=Homo sapiens OX=9606 GN=CCT3 PE=1 SV=4 6.85 1506.6 - 7.00E+06 - - - -0.8274 - 1.364 0.173 - 161.5 1 2 0 -0.0009 10 0 0 0 2.22E+08 4.45E+08 - - - 1.185 0.9999 221125_WJC_METTL3_EV_vs_WT_F07.05437.05437.3 0.000128 Dec-40 R.LSSVVTQHDSK[136.11].K "sp|P54577|SYYC_HUMAN,tr|A0A6Q8PFX4|A0A6Q8PFX4_HUMAN,tr|A0A6Q8PF15|A0A6Q8PF15_HUMAN,tr|A0A0C4DGZ5|A0A0C4DGZ5_HUMAN,tr|A0A6Q8PFX2|A0A6Q8PFX2_HUMAN" 5 1207.6288 0.84 94392 5437 3 1207.626964 403.5502 "Tyrosine--tRNA ligase, cytoplasmic OS=Homo sapiens OX=9606 GN=YARS1 PE=1 SV=4" 6.74 1506.7 - 5.77E+06 - - - -1.5336 - 1.826 0.438 - 140.6 1 2 0 -0.0019 11 0 0 0 7.27E+07 8.68E+07 - - - 5.1333 0.9992 221125_WJC_METTL3_EV_vs_WT_F07.05440.05440.2 0.0692 16-Sep R.RYDDPEVQK.D "sp|P38646|GRP75_HUMAN,tr|H0Y8K0|H0Y8K0_HUMAN,tr|A0A7I2V2S7|A0A7I2V2S7_HUMAN,tr|A0A7I2V2G2|A0A7I2V2G2_HUMAN,tr|A0A3B3ITI4|A0A3B3ITI4_HUMAN,tr|A0A7I2V3F7|A0A7I2V3F7_HUMAN,tr|A0A7I2YQB2|A0A7I2YQB2_HUMAN,tr|D6RCD7|D6RCD7_HUMAN" 8 1148.5462 0.44 94395 5440 2 1148.543302 575.2804 "Stress-70 protein, mitochondrial OS=Homo sapiens OX=9606 GN=HSPA9 PE=1 SV=2" 4.56 1506.8 - 3.94E+06 - - - -2.5249 - 2.058 0.351 - 306.7 1 2 0 -0.0029 9 0 0 0 3.22E+08 7.27E+08 - - - 3.7206 0.9996 221125_WJC_METTL3_EV_vs_WT_F07.05443.05443.2 0.0133 12-Jun R.YHSDFNR.Q "sp|Q15424|SAFB1_HUMAN,tr|K7EII0|K7EII0_HUMAN" 2 937.4042 1.32 94398 5443 2 937.403591 469.7094 Scaffold attachment factor B1 OS=Homo sapiens OX=9606 GN=SAFB PE=1 SV=4 6.74 1507.1 - 730759 - - - -0.6806 - 1.435 0.411 - 199 1 2 0 -0.0006 7 0 0 0 5.30E+07 4.02E+07 - - - 3.2208 0.9374 221125_WJC_METTL3_EV_vs_WT_F07.05447.05447.2 2.84E-05 20-Nov N.AAHVEYSTAAR[166.11].H sp|P49411|EFTU_HUMAN 1 1184.5814 1.14 94401 5447 2 1184.576838 593.298 "Elongation factor Tu, mitochondrial OS=Homo sapiens OX=9606 GN=TUFM PE=1 SV=2" 6.79 1507.6 - 1.10E+06 - - - -3.8132 - 2.017 0.502 - 304.3 1 1 0 -0.0045 11 0 0 0 1.23E+07 1.08E+07 - - - 4.6454 0.9999 221125_WJC_METTL3_EV_vs_WT_F07.05451.05451.2 4.40E-07 20-Nov K.MENEEQPQDER.K "sp|Q96EI5|TCAL4_HUMAN,tr|D6RD44|D6RD44_HUMAN,tr|D6RCE9|D6RCE9_HUMAN,tr|J3KQY4|J3KQY4_HUMAN,tr|A2RQR6|A2RQR6_HUMAN,tr|D6RIH3|D6RIH3_HUMAN,tr|D6RHZ1|D6RHZ1_HUMAN" 7 1403.5623 1.21 94404 5451 2 1403.560987 702.7884 Transcription elongation factor A protein-like 4 OS=Homo sapiens OX=9606 GN=TCEAL4 PE=1 SV=2 3.91 1508 - 936436 - - - -0.9512 - 2.413 0.54 - 431.9 1 2 0 -0.0013 11 0 0 0 5.00E+06 4.13E+06 - - - 5.412 0.9377 221125_WJC_METTL3_EV_vs_WT_F07.05452.05452.2 0.042 24-Aug K.AEGPGR[166.11]GDEPSPS.- "sp|Q9NVI7|ATD3A_HUMAN,tr|Q5SV16|Q5SV16_HUMAN" 2 1264.5559 1.31 94405 5452 2 1264.55134 633.2852 ATPase family AAA domain-containing protein 3A OS=Homo sapiens OX=9606 GN=ATAD3A PE=1 SV=2 4.14 1508.1 - 686894 - - - -3.6289 - 1.453 0.343 - 101.1 1 2 1 -0.0046 13 0 0 0 3.58E+07 2.73E+07 - - - 2.5319 0.9973 221125_WJC_METTL3_EV_vs_WT_F07.05456.05456.3 2.39 Oct-36 R.IDDSKEAMER.A sp|Q13595|TRA2A_HUMAN 1 1192.5394 1.39 94407 5456 3 1192.539404 398.5204 Transformer-2 protein homolog alpha OS=Homo sapiens OX=9606 GN=TRA2A PE=1 SV=1 4.32 1508.5 - 1.41E+06 - - - 0.0017 - 1.97 0.285 - 116 1 2 1 0 10 0 0 0 5.65E+07 4.07E+07 - - - 3.6976 0.9994 221125_WJC_METTL3_EV_vs_WT_F07.05457.05457.3 3.37E-05 Oct-36 R.ERPPEEVAAR.L "sp|Q16891|MIC60_HUMAN,tr|B9A067|B9A067_HUMAN,tr|A0A087WYS0|A0A087WYS0_HUMAN,tr|C9J406|C9J406_HUMAN" 4 1152.5887 1.18 94408 5457 3 1152.587205 385.2035 MICOS complex subunit MIC60 OS=Homo sapiens OX=9606 GN=IMMT PE=1 SV=1 4.79 1508.6 - 1.39E+07 - - - -1.3283 - 2.247 0.264 - 220 1 2 0 -0.0015 10 0 0 0 1.14E+09 9.71E+08 - - - 3.8473 1 221125_WJC_METTL3_EV_vs_WT_F07.05462.05462.2 0.000267 20-Nov K.MENEEQPQDER[166.11].K "sp|Q96EI5|TCAL4_HUMAN,tr|D6RD44|D6RD44_HUMAN,tr|D6RCE9|D6RCE9_HUMAN,tr|J3KQY4|J3KQY4_HUMAN,tr|A2RQR6|A2RQR6_HUMAN,tr|D6RIH3|D6RIH3_HUMAN,tr|D6RHZ1|D6RHZ1_HUMAN" 7 1413.5706 1.21 94413 5462 2 1413.56892 707.7926 Transcription elongation factor A protein-like 4 OS=Homo sapiens OX=9606 GN=TCEAL4 PE=1 SV=2 3.91 1509 - 399200 - - - -1.1828 - 2.192 0.663 - 431.7 1 2 0 -0.0017 11 0 0 0 5.00E+06 4.13E+06 - - - 6.0605 0.9997 221125_WJC_METTL3_EV_vs_WT_F07.05468.05468.2 0.0336 16-Sep K.KEEGEAFAR.E "sp|P61019|RAB2A_HUMAN,tr|H7C125|H7C125_HUMAN" 2 1035.4985 0.83 94417 5468 2 1035.497838 518.7565 Ras-related protein Rab-2A OS=Homo sapiens OX=9606 GN=RAB2A PE=1 SV=1 4.79 1509.7 - 4.93E+06 - - - -0.6615 - 1.796 0.395 - 288.4 1 2 0 -0.0007 9 0 0 0 1.06E+08 1.28E+08 - - - 3.6523 0.9996 221125_WJC_METTL3_EV_vs_WT_F07.05471.05471.2 0.00521 16-Sep K.KLENEVEQR.H sp|P12270|TPR_HUMAN 1 1143.5884 4.47 94420 5471 2 1143.58656 572.8015 Nucleoprotein TPR OS=Homo sapiens OX=9606 GN=TPR PE=1 SV=3 4.79 1509.8 - 2.68E+06 - - - -1.6098 - 2.011 0.382 - 301.4 1 2 0 -0.0018 9 0 0 0 2.76E+07 6.17E+06 - - - 3.8831 0.9983 221125_WJC_METTL3_EV_vs_WT_F07.05477.05477.2 0.128 12-Jun R.YHSDFNR[166.11].Q "sp|Q15424|SAFB1_HUMAN,tr|K7EII0|K7EII0_HUMAN" 2 947.4125 1.32 94424 5477 2 947.411066 474.7135 Scaffold attachment factor B1 OS=Homo sapiens OX=9606 GN=SAFB PE=1 SV=4 6.74 1510.5 - 4.12E+06 - - - -1.5125 - 1.207 0.358 - 204 1 2 0 -0.0014 7 0 0 0 5.30E+07 4.02E+07 - - - 2.2809 0.9944 221125_WJC_METTL3_EV_vs_WT_F07.05478.05478.3 0.0809 Oct-40 K.FKQESTVATER.Q sp|Q9H307|PININ_HUMAN 1 1294.6517 1.55 94425 5478 3 1294.650966 432.5579 Pinin OS=Homo sapiens OX=9606 GN=PNN PE=1 SV=5 6.14 1510.6 - 2.63E+06 - - - -0.5901 - 1.992 0.24 - 156.3 1 2 1 -0.0008 11 0 0 0 3.62E+08 2.33E+08 - - - 3.1733 0.9999 221125_WJC_METTL3_EV_vs_WT_F07.05482.05482.2 0.000909 16/24 R.LEGGSGGDSEVQR[166.11].T "sp|P62195|PRS8_HUMAN,tr|J3QQM1|J3QQM1_HUMAN" 2 1299.593 0.76 94429 5482 2 1299.591618 650.8038 26S proteasome regulatory subunit 8 OS=Homo sapiens OX=9606 GN=PSMC5 PE=1 SV=1 4.14 1510.9 - 1.73E+06 - - - -1.0957 - 2.838 0.521 - 922.3 1 2 0 -0.0014 13 0 0 0 1.01E+08 1.33E+08 - - - 5.5658 0.9959 221125_WJC_METTL3_EV_vs_WT_F07.05483.05483.2 0.000538 18-Sep R.IDDSKEAMER.A sp|Q13595|TRA2A_HUMAN 1 1192.5394 0.94 94430 5483 2 1192.537045 597.277 Transformer-2 protein homolog alpha OS=Homo sapiens OX=9606 GN=TRA2A PE=1 SV=1 4.32 1511.1 - 693323 - - - -1.9765 - 2.122 0.428 - 291.3 1 2 1 -0.0024 10 0 0 0 8.42E+06 8.95E+06 - - - 4.3015 0.9998 221125_WJC_METTL3_EV_vs_WT_F07.05485.05485.2 0.000104 16-Dec R.R[166.11]YDDPEVQK[136.11].D "sp|P38646|GRP75_HUMAN,tr|H0Y8K0|H0Y8K0_HUMAN,tr|A0A7I2V2S7|A0A7I2V2S7_HUMAN,tr|A0A7I2V2G2|A0A7I2V2G2_HUMAN,tr|A0A3B3ITI4|A0A3B3ITI4_HUMAN,tr|A0A7I2V3F7|A0A7I2V3F7_HUMAN,tr|A0A7I2YQB2|A0A7I2YQB2_HUMAN,tr|D6RCD7|D6RCD7_HUMAN" 8 1166.5687 0.44 94431 5485 2 1166.567146 584.2916 "Stress-70 protein, mitochondrial OS=Homo sapiens OX=9606 GN=HSPA9 PE=1 SV=2" 4.56 1511.3 - 4.54E+07 - - - -1.3081 - 2.411 0.441 - 645.1 1 2 0 -0.0015 9 0 0 0 3.22E+08 7.27E+08 - - - 4.8438 0.9999 221125_WJC_METTL3_EV_vs_WT_F07.05486.05486.3 0.00062 13/36 R.ER[166.11]PPEEVAAR[166.11].L "sp|Q16891|MIC60_HUMAN,tr|B9A067|B9A067_HUMAN,tr|A0A087WYS0|A0A087WYS0_HUMAN,tr|C9J406|C9J406_HUMAN" 4 1172.6053 1.45 94432 5486 3 1172.603183 391.8757 MICOS complex subunit MIC60 OS=Homo sapiens OX=9606 GN=IMMT PE=1 SV=1 4.79 1511.3 - 3.93E+07 - - - -1.7849 - 2.664 0.389 - 367.9 1 2 0 -0.0021 10 0 0 0 1.12E+09 7.77E+08 - - - 5.7379 0.9998 221125_WJC_METTL3_EV_vs_WT_F07.05487.05487.2 0.000282 16-Oct R.KAQC[160.03]PIVER.L "sp|P46782|RS5_HUMAN,tr|M0R0F0|M0R0F0_HUMAN,tr|M0R0R2|M0R0R2_HUMAN" 3 1099.5808 0.84 94433 5487 2 1099.58039 550.7977 40S ribosomal protein S5 OS=Homo sapiens OX=9606 GN=RPS5 PE=1 SV=4 8.22 1511.3 - 7.89E+06 - - - -0.3856 - 2.21 0.408 - 417.7 1 2 0 -0.0004 9 0 0 0 5.05E+08 6.02E+08 - - - 4.3485 0.9999 221125_WJC_METTL3_EV_vs_WT_F07.05488.05488.2 0.000687 13/24 R.LEGGSGGDSEVQR.T "sp|P62195|PRS8_HUMAN,tr|J3QQM1|J3QQM1_HUMAN" 2 1289.5848 0.76 94434 5488 2 1289.583694 645.7997 26S proteasome regulatory subunit 8 OS=Homo sapiens OX=9606 GN=PSMC5 PE=1 SV=1 4.14 1511.4 - 3.05E+06 - - - -0.8359 - 2.626 0.526 - 506.6 1 2 0 -0.0011 13 0 0 0 1.01E+08 1.33E+08 - - - 5.4036 0.9983 221125_WJC_METTL3_EV_vs_WT_F07.05492.05492.2 0.00127 20-Dec K.FKQESTVATER.Q sp|Q9H307|PININ_HUMAN 1 1294.6517 1.83 94438 5492 2 1294.651009 648.3331 Pinin OS=Homo sapiens OX=9606 GN=PNN PE=1 SV=5 6.14 1511.7 - 1.49E+06 - - - -0.5569 - 2.141 0.466 - 394.7 1 2 1 -0.0007 11 0 0 0 6.39E+07 3.50E+07 - - - 4.5421 0.9991 221125_WJC_METTL3_EV_vs_WT_F07.05497.05497.2 0.278 20-Sep R.NEEEGNSEEIK.A sp|O75844|FACE1_HUMAN 1 1276.5419 1.17 94440 5497 2 1276.5394 639.2782 CAAX prenyl protease 1 homolog OS=Homo sapiens OX=9606 GN=ZMPSTE24 PE=1 SV=2 3.98 1512.4 - 827714 - - - -1.9623 - 1.883 0.324 - 185.7 1 2 0 -0.0025 11 0 0 0 4.87E+07 4.17E+07 - - - 3.1453 0.9529 221125_WJC_METTL3_EV_vs_WT_F07.05502.05502.2 2.30E-05 20-Nov M.TTVHAITATQK[136.11].T "sp|P04406|G3P_HUMAN,tr|E7EUT5|E7EUT5_HUMAN" 2 1177.6546 1.14 94442 5502 2 1177.657937 589.8346 Glyceraldehyde-3-phosphate dehydrogenase OS=Homo sapiens OX=9606 GN=GAPDH PE=1 SV=3 8.44 1513.1 - 1.48E+06 - - - 2.8022 - 2.079 0.409 - 321.8 1 1 0 0.0033 11 0 0 0 2.96E+07 2.59E+07 - - - 4.0408 0.9999 221125_WJC_METTL3_EV_vs_WT_F07.05503.05503.2 2.38E-05 13/24 K.GALTTQDENGQTK[136.11].R "sp|Q9ULX6|AKP8L_HUMAN,tr|A0A7P0T9N5|A0A7P0T9N5_HUMAN,tr|A0A7P0TAD3|A0A7P0TAD3_HUMAN,tr|V9GZ50|V9GZ50_HUMAN,tr|A0A7P0TBP0|A0A7P0TBP0_HUMAN,tr|A0A7P0TAJ5|A0A7P0TAJ5_HUMAN,tr|A0A7P0TAE3|A0A7P0TAE3_HUMAN" 7 1369.6565 1.31 94443 5503 2 1369.654849 685.8355 A-kinase anchor protein 8-like OS=Homo sapiens OX=9606 GN=AKAP8L PE=1 SV=4 4.37 1513.2 - 550856 - - - -1.1959 - 2.637 0.506 - 400.9 1 2 0 -0.0016 13 0 0 0 1.09E+07 8.35E+06 - - - 5.2664 0.9799 221125_WJC_METTL3_EV_vs_WT_F07.05505.05505.2 0.392 13/20 R.NEEEGNSEEIK[136.11].A sp|O75844|FACE1_HUMAN 1 1284.5561 1.17 94445 5505 2 1284.547222 643.2853 CAAX prenyl protease 1 homolog OS=Homo sapiens OX=9606 GN=ZMPSTE24 PE=1 SV=2 3.98 1513.4 - 894175 - - - -6.9152 - 2.127 0.346 - 722.4 1 2 0 -0.0089 11 0 0 0 4.87E+07 4.17E+07 - - - 3.6354 0.9999 221125_WJC_METTL3_EV_vs_WT_F07.05506.05506.2 2.86E-05 24-Dec K.GALTTQDENGQTK.R "sp|Q9ULX6|AKP8L_HUMAN,tr|A0A7P0T9N5|A0A7P0T9N5_HUMAN,tr|A0A7P0TAD3|A0A7P0TAD3_HUMAN,tr|V9GZ50|V9GZ50_HUMAN,tr|A0A7P0TBP0|A0A7P0TBP0_HUMAN,tr|A0A7P0TAJ5|A0A7P0TAJ5_HUMAN,tr|A0A7P0TAE3|A0A7P0TAE3_HUMAN" 7 1361.6423 1.31 94446 5506 2 1361.642008 681.8284 A-kinase anchor protein 8-like OS=Homo sapiens OX=9606 GN=AKAP8L PE=1 SV=4 4.37 1513.6 - 876669 - - - -0.2049 - 2.543 0.464 - 455.8 1 2 0 -0.0003 13 0 0 0 1.09E+07 8.35E+06 - - - 4.8635 0.9982 221125_WJC_METTL3_EV_vs_WT_F07.05509.05509.3 0.0544 Nov-40 K.LDGEASINNRK.G "sp|O95433|AHSA1_HUMAN,tr|G3V3W9|G3V3W9_HUMAN,tr|H0YJG7|H0YJG7_HUMAN" 3 1215.6208 1.1 94447 5509 3 1215.618783 406.2142 Activator of 90 kDa heat shock protein ATPase homolog 1 OS=Homo sapiens OX=9606 GN=AHSA1 PE=1 SV=1 6.07 1514 - 3.45E+06 - - - -1.6296 - 1.992 0.238 - 126.7 1 2 0 -0.002 11 0 0 0 3.04E+07 2.77E+07 - - - 3.1506 0.9998 221125_WJC_METTL3_EV_vs_WT_F07.05511.05511.2 0.955 13/20 K.TSETLSQAGQK[136.11].A "sp|P55327|TPD52_HUMAN,tr|H0YC42|H0YC42_HUMAN" 2 1156.5815 0.51 94449 5511 2 1156.581056 579.298 Tumor protein D52 OS=Homo sapiens OX=9606 GN=TPD52 PE=1 SV=2 5.66 1514.1 - 5.91E+06 - - - -0.4107 - 2.495 0.378 - 916 1 2 0 -0.0005 11 0 0 0 4.98E+07 9.82E+07 - - - 4.3061 1 221125_WJC_METTL3_EV_vs_WT_F07.05513.05513.3 7.51E-06 Dec-36 R.K[136.11]QDSGHLDLR[166.11].N "sp|Q86U44|MTA70_HUMAN,tr|B4E349|B4E349_HUMAN,tr|F5H6D8|F5H6D8_HUMAN,tr|B4DTN4|B4DTN4_HUMAN" 4 1185.6221 1.78 94451 5513 3 1185.620941 396.2146 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 6.75 1514.1 - 4.18E+06 - - - -0.9818 - 2.457 0.517 - 191.9 1 2 0 -0.0012 10 0 0 0 2.49E+08 1.40E+08 - - - 6.929 0.9984 221125_WJC_METTL3_EV_vs_WT_F07.05514.05514.2 0.000141 16-Oct R.FK[136.11]GTESISK[136.11].V sp|Q00688|FKBP3_HUMAN 1 1011.5572 0.01 94452 5514 2 1011.556472 506.7859 Peptidyl-prolyl cis-trans isomerase FKBP3 OS=Homo sapiens OX=9606 GN=FKBP3 PE=1 SV=1 8.59 1514.2 - 3.85E+06 - - - -0.6811 - 2.23 0.443 - 203.6 1 2 1 -0.0007 9 0 0 0 4.97E+05 5.13E+07 - - - 4.633 0.998 221125_WJC_METTL3_EV_vs_WT_F07.05519.05519.2 0.000958 13/20 K.FK[136.11]QESTVATER[166.11].Q sp|Q9H307|PININ_HUMAN 1 1312.6742 1.83 94456 5519 2 1312.673079 657.3444 Pinin OS=Homo sapiens OX=9606 GN=PNN PE=1 SV=5 6.14 1514.7 - 2.28E+06 - - - -0.854 - 2.219 0.439 - 423.7 1 2 1 -0.0011 11 0 0 0 6.39E+07 3.50E+07 - - - 4.4393 0.9998 221125_WJC_METTL3_EV_vs_WT_F07.05524.05524.2 0.000139 14-Sep K.YHNVGLSK[136.11].C "sp|Q14103|HNRPD_HUMAN,tr|H0Y8G5|H0Y8G5_HUMAN,tr|H0YA96|H0YA96_HUMAN" 3 924.4909 1.39 94460 5524 2 924.491352 463.2527 Heterogeneous nuclear ribonucleoprotein D0 OS=Homo sapiens OX=9606 GN=HNRNPD PE=1 SV=1 8.6 1515.2 - 1.47E+06 - - - 0.5257 - 1.888 0.455 - 364.3 1 2 0 0.0005 8 0 0 0 2.51E+07 1.81E+07 - - - 4.3182 0.9993 221125_WJC_METTL3_EV_vs_WT_F07.05525.05525.2 0.0114 22-Nov R.ENMAPANSEATK[136.11].E "sp|Q6WKZ4|RFIP1_HUMAN,tr|E7EX40|E7EX40_HUMAN" 2 1269.5751 1.75 94461 5525 2 1269.573042 635.7948 Rab11 family-interacting protein 1 OS=Homo sapiens OX=9606 GN=RAB11FIP1 PE=1 SV=3 4.53 1515.3 - 480215 - - - -1.5942 - 1.855 0.339 - 379 1 2 0 -0.002 12 0 0 0 2.82E+07 1.61E+07 - - - 3.17 0.9748 221125_WJC_METTL3_EV_vs_WT_F07.05528.05528.2 0.00359 14-Sep Y.AVHQEGNK[136.11].N "sp|P50990|TCPQ_HUMAN,tr|H7C2U0|H7C2U0_HUMAN" 2 889.4497 0.36 94462 5528 2 889.448716 445.7321 T-complex protein 1 subunit theta OS=Homo sapiens OX=9606 GN=CCT8 PE=1 SV=4 6.79 1515.7 - 4.45E+06 - - - -1.1389 - 1.764 0.364 - 289.3 1 1 0 -0.001 8 0 0 0 2.35E+07 6.50E+07 - - - 3.441 0.9988 221125_WJC_METTL3_EV_vs_WT_F07.05529.05529.2 0.0299 16-Jul R.SSPATADKR.Q "sp|Q8TF72|SHRM3_HUMAN,tr|A0A2R8Y5P9|A0A2R8Y5P9_HUMAN" 2 931.4723 14.54 94463 5529 2 931.47125 466.7434 Protein Shroom3 OS=Homo sapiens OX=9606 GN=SHROOM3 PE=1 SV=2 8.46 1515.8 - 1.75E+06 - - - -1.1369 - 1.546 0.287 - 166.2 1 2 0 -0.0011 9 0 0 0 8.51E+07 5.85E+06 - - - 2.4209 0.965 221125_WJC_METTL3_EV_vs_WT_F07.05530.05530.2 0.000907 13/18 M.K[136.11]SAVEDEGLK[136.11].G "sp|P0DMV8|HS71A_HUMAN,sp|P0DMV9|HS71B_HUMAN,tr|V9GZ37|V9GZ37_HUMAN,tr|A0A0G2JIW1|A0A0G2JIW1_HUMAN" 4 1090.5841 0.64 94464 5530 2 1090.580611 546.2993 Heat shock 70 kDa protein 1A OS=Homo sapiens OX=9606 GN=HSPA1A PE=1 SV=1 4.68 1515.9 - 3.23E+06 - - - -3.2029 - 2.546 0.444 - 468.4 1 1 0 -0.0035 10 0 0 0 2.17E+07 3.38E+07 - - - 4.9278 0.9985 221125_WJC_METTL3_EV_vs_WT_F07.05533.05533.2 0.00619 14-Jul K.YHNVGLSK.C "sp|Q14103|HNRPD_HUMAN,tr|H0Y8G5|H0Y8G5_HUMAN,tr|H0YA96|H0YA96_HUMAN" 3 916.4767 1.34 94467 5533 2 916.477918 459.2456 Heterogeneous nuclear ribonucleoprotein D0 OS=Homo sapiens OX=9606 GN=HNRNPD PE=1 SV=1 8.6 1516 - 1.45E+06 - - - 1.3661 - 1.501 0.292 - 173.3 1 2 0 0.0013 8 0 0 0 2.43E+07 1.81E+07 - - - 2.4222 0.9999 221125_WJC_METTL3_EV_vs_WT_F07.05534.05534.2 0.00965 13/16 K.K[136.11]VVDYTTAK[136.11].E "sp|P62820|RAB1A_HUMAN,tr|E7END7|E7END7_HUMAN" 2 1039.5885 1.17 94468 5534 2 1039.587789 520.8015 Ras-related protein Rab-1A OS=Homo sapiens OX=9606 GN=RAB1A PE=1 SV=3 8.5 1516.2 - 1.29E+06 - - - -0.6464 - 2.556 0.401 - 530.1 1 2 0 -0.0007 9 0 0 0 1.11E+08 9.46E+07 - - - 4.7175 0.9998 221125_WJC_METTL3_EV_vs_WT_F07.05536.05536.2 8.22E-05 22-Nov R.ENMAPANSEATK.E "sp|Q6WKZ4|RFIP1_HUMAN,tr|E7EX40|E7EX40_HUMAN" 2 1261.5609 1.37 94470 5536 2 1261.559269 631.7877 Rab11 family-interacting protein 1 OS=Homo sapiens OX=9606 GN=RAB11FIP1 PE=1 SV=3 4.53 1516.3 - 713676 - - - -1.2659 - 1.923 0.5 - 365.9 1 2 0 -0.0016 12 0 0 0 1.33E+07 9.70E+06 - - - 4.454 0.9999 221125_WJC_METTL3_EV_vs_WT_F07.05542.05542.2 0.000178 16-Nov K.KVVDYTTAK.E "sp|P62820|RAB1A_HUMAN,tr|E7END7|E7END7_HUMAN" 2 1023.5601 1.17 94473 5542 2 1023.558981 512.7873 Ras-related protein Rab-1A OS=Homo sapiens OX=9606 GN=RAB1A PE=1 SV=3 8.5 1517.1 - 5.17E+06 - - - -1.0551 - 2.383 0.489 - 450.2 1 2 0 -0.0011 9 0 0 0 1.11E+08 9.46E+07 - - - 5.1646 0.9875 221125_WJC_METTL3_EV_vs_WT_F07.05545.05545.3 0.616 Oct-48 R.MAQPAWGLSASHR.A tr|Q5T4F6|Q5T4F6_HUMAN 1 1410.6827 61.67 94476 5545 3 1410.683706 471.2348 Cartilage acidic protein 1 (Fragment) OS=Homo sapiens OX=9606 GN=CRTAC1 PE=1 SV=1 9.52 1517.4 - 998630 - - - 0.7464 - 1.74 0.146 - 81.3 1 2 0 0.0011 13 0 0 0 2.56E+07 4.16E+05 - - - 1.6692 0.9976 221125_WJC_METTL3_EV_vs_WT_F07.05549.05549.2 0.187 14-Sep R.RIDTNLNK.V "sp|P21912|SDHB_HUMAN,tr|A0A087WWT1|A0A087WWT1_HUMAN,tr|A0A087WXX8|A0A087WXX8_HUMAN" 3 972.5352 0.58 94478 5549 2 972.534562 487.2749 "Succinate dehydrogenase [ubiquinone] iron-sulfur subunit, mitochondrial OS=Homo sapiens OX=9606 GN=SDHB PE=1 SV=3" 8.75 1518 - 5.45E+06 - - - -0.7002 - 1.564 0.178 - 318.8 1 2 0 -0.0007 8 0 0 0 7.06E+07 1.21E+08 - - - 1.7044 0.9999 221125_WJC_METTL3_EV_vs_WT_F07.05550.05550.2 2.15E-07 24-Dec R.GVGSGGQGPPPPR[166.11].R sp|P48634|PRC2A_HUMAN 1 1171.5973 0.52 94479 5550 2 1171.596568 586.8059 Protein PRRC2A OS=Homo sapiens OX=9606 GN=PRRC2A PE=1 SV=3 9.75 1518 - 5.16E+06 - - - -0.6589 - 2.53 0.566 - 512.5 1 2 0 -0.0008 13 0 0 0 9.29E+07 1.79E+08 - - - 5.6035 0.9707 221125_WJC_METTL3_EV_vs_WT_F07.05557.05557.2 0.87 18-May R.K[136.11]QDSGHLDLR[166.11].N "sp|Q86U44|MTA70_HUMAN,tr|B4E349|B4E349_HUMAN,tr|F5H6D8|F5H6D8_HUMAN,tr|B4DTN4|B4DTN4_HUMAN" 4 1185.6221 4.41 94484 5557 2 1185.62417 593.8183 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 6.75 1518.9 - 345500 - - - 1.7417 - 1.179 0.157 - 66 5 2 0 0.0021 10 0 0 0 2.45E+07 5.55E+06 - - - 0.3474 0.9923 221125_WJC_METTL3_EV_vs_WT_F07.05560.05560.2 0.147 12-Aug K.SKEYFSK.Q "sp|Q06830|PRDX1_HUMAN,sp|P32119|PRDX2_HUMAN,tr|A0A0A0MRQ5|A0A0A0MRQ5_HUMAN" 3 887.4389 0.61 94485 5560 2 887.438855 444.7267 Peroxiredoxin-1 OS=Homo sapiens OX=9606 GN=PRDX1 PE=1 SV=1 8.22 1519.3 - 1.38E+07 - - - -0.0316 - 1.61 0.292 - 222.5 1 2 1 0 7 0 0 0 1.66E+08 2.72E+08 - - - 2.7067 0.9999 221125_WJC_METTL3_EV_vs_WT_F07.05561.05561.3 0.00407 Nov-40 R.VDSFHESTEGK.V "sp|Q8WWY3|PRP31_HUMAN,tr|E7EVX8|E7EVX8_HUMAN" 2 1234.5466 2.32 94486 5561 3 1234.546465 412.5228 U4\U6 small nuclear ribonucleoprotein Prp31 OS=Homo sapiens OX=9606 GN=PRPF31 PE=1 SV=2 4.65 1519.4 - 7.71E+06 - - - -0.1061 - 2.144 0.426 - 228.3 1 2 0 -0.0001 11 0 0 0 1.64E+08 7.08E+07 - - - 5.4561 1 221125_WJC_METTL3_EV_vs_WT_F07.05562.05562.2 8.81E-05 15/24 R.GVGSGGQGPPPPR.R sp|P48634|PRC2A_HUMAN 1 1161.5891 0.51 94487 5562 2 1161.589297 581.8018 Protein PRRC2A OS=Homo sapiens OX=9606 GN=PRRC2A PE=1 SV=3 9.75 1519.4 - 4.48E+06 - - - 0.1954 - 2.93 0.562 - 861.4 1 2 0 0.0002 13 0 0 0 9.04E+07 1.76E+08 - - - 5.9509 0.9961 221125_WJC_METTL3_EV_vs_WT_F07.05563.05563.3 0.242 Sep-36 R.LQSEPESIR[166.11]K[136.11].W "sp|P09496|CLCA_HUMAN,tr|F8WF69|F8WF69_HUMAN" 2 1203.6578 0.28 94488 5563 3 1203.657168 402.2266 Clathrin light chain A OS=Homo sapiens OX=9606 GN=CLTA PE=1 SV=1 6.14 1519.4 - 3.12E+06 - - - -0.5425 - 1.723 0.203 - 92 1 2 0 -0.0007 10 0 0 0 5.07E+07 1.80E+08 - - - 2.392 0.999 221125_WJC_METTL3_EV_vs_WT_F07.05572.05572.2 0.000652 16-Oct K.NLHSEISGK.R sp|P15924|DESP_HUMAN 1 983.5036 18.44 94495 5572 2 983.502854 492.7591 Desmoplakin OS=Homo sapiens OX=9606 GN=DSP PE=1 SV=3 6.75 1520.4 - 5.33E+06 - - - -0.7677 - 1.887 0.214 - 366.8 1 2 0 -0.0008 9 0 0 0 1.80E+08 9.78E+06 - - - 2.4584 0.9999 221125_WJC_METTL3_EV_vs_WT_F07.05573.05573.2 1.92E-05 20-Nov K.TQETLSQAGQK.T "sp|O43399|TPD54_HUMAN,tr|A0A087WYR3|A0A087WYR3_HUMAN" 2 1189.5939 1.56 94496 5573 2 1189.594735 595.8042 Tumor protein D54 OS=Homo sapiens OX=9606 GN=TPD52L2 PE=1 SV=2 5.66 1520.5 - 3.35E+06 - - - 0.7179 - 2.243 0.554 - 451.7 1 2 0 0.0009 11 0 0 0 1.24E+08 7.95E+07 - - - 5.3179 1 221125_WJC_METTL3_EV_vs_WT_F07.05574.05574.3 0.00238 Nov-40 R.VDSFHESTEGK[136.11].V "sp|Q8WWY3|PRP31_HUMAN,tr|E7EVX8|E7EVX8_HUMAN" 2 1242.5608 2.32 94497 5574 3 1242.560629 415.1942 U4\U6 small nuclear ribonucleoprotein Prp31 OS=Homo sapiens OX=9606 GN=PRPF31 PE=1 SV=2 4.65 1520.5 - 7.93E+06 - - - -0.1344 - 2.13 0.494 - 231.7 1 2 0 -0.0002 11 0 0 0 1.64E+08 7.09E+07 - - - 6.1956 0.9904 221125_WJC_METTL3_EV_vs_WT_F07.05576.05576.3 0.0211 Sep-40 R.LNGTLREDDNR.L "sp|Q15637|SF01_HUMAN,tr|A0A7P0T9U7|A0A7P0T9U7_HUMAN" 2 1301.6324 1.09 94499 5576 3 1301.632289 434.8847 Splicing factor 1 OS=Homo sapiens OX=9606 GN=SF1 PE=1 SV=4 4.56 1520.6 - 1.99E+06 - - - -0.0784 - 1.724 0.243 - 105.6 1 2 1 -0.0001 11 0 0 0 2.39E+07 2.18E+07 - - - 2.7964 1 221125_WJC_METTL3_EV_vs_WT_F07.05577.05577.2 2.46E-07 13/18 V.DSFHESTEGK.V "sp|Q8WWY3|PRP31_HUMAN,tr|E7EVX8|E7EVX8_HUMAN" 2 1135.4782 3.12 94500 5577 2 1135.478505 568.7464 U4\U6 small nuclear ribonucleoprotein Prp31 OS=Homo sapiens OX=9606 GN=PRPF31 PE=1 SV=2 4.65 1520.7 - 1.38E+06 - - - 0.2845 - 2.443 0.607 - 698.8 1 1 0 0.0003 10 0 0 0 1.32E+07 4.23E+06 - - - 6.0175 0.9996 221125_WJC_METTL3_EV_vs_WT_F07.05578.05578.2 0.00237 12-Jul R.FNIHNNR[166.11].K sp|Q96KR1|ZFR_HUMAN 1 923.4601 1.24 94501 5578 2 923.459296 462.7373 Zinc finger RNA-binding protein OS=Homo sapiens OX=9606 GN=ZFR PE=1 SV=2 9.76 1520.8 - 1.32E+06 - - - -0.8901 - 1.56 0.411 - 226.4 1 2 0 -0.0008 7 0 0 0 1.47E+07 1.18E+07 - - - 3.4854 0.9999 221125_WJC_METTL3_EV_vs_WT_F07.05580.05580.2 1.97E-06 20-Oct R.EAEC[160.03]VEADSGR.L "sp|Q14533|KRT81_HUMAN,sp|P78386|KRT85_HUMAN,sp|O43790|KRT86_HUMAN,sp|P78385|KRT83_HUMAN,tr|A0A087X106|A0A087X106_HUMAN" 5 1221.4932 18.43 94503 5580 2 1221.492275 611.7539 "Keratin, type II cuticular Hb1 OS=Homo sapiens OX=9606 GN=KRT81 PE=1 SV=3" 4 1521 - 753696 - - - -0.7409 - 2.177 0.596 - 467.1 1 2 0 -0.0009 11 0 0 0 4.72E+06 2.56E+05 - - - 5.5473 0.9766 221125_WJC_METTL3_EV_vs_WT_F07.05581.05581.2 0.000448 20-Nov Y.SQLAHPIQQAK[136.11].A sp|O43615|TIM44_HUMAN 1 1227.6815 1.23 94504 5581 2 1227.678949 614.848 Mitochondrial import inner membrane translocase subunit TIM44 OS=Homo sapiens OX=9606 GN=TIMM44 PE=1 SV=2 8.49 1521.2 - 313887 - - - -2.0942 - 2.305 0.404 - 437 1 1 0 -0.0026 11 0 0 0 2.81E+06 2.29E+06 - - - 4.2832 0.9999 221125_WJC_METTL3_EV_vs_WT_F07.05582.05582.2 2.72E-05 20-Sep R.C[160.03]PVC[160.03]SQEC[160.03]AER.H sp|O15164|TIF1A_HUMAN 1 1394.5377 0.87 94505 5582 2 1394.535887 698.2761 Transcription intermediary factor 1-alpha OS=Homo sapiens OX=9606 GN=TRIM24 PE=1 SV=3 4.53 1521.3 - 275494 - - - -1.3037 - 1.741 0.613 - 261 1 2 0 -0.0018 11 0 0 0 1.69E+06 1.94E+06 - - - 5.068 0.9641 221125_WJC_METTL3_EV_vs_WT_F07.05586.05586.2 2.6 12-May K.EQSIVEK[136.11].F "sp|Q86U44|MTA70_HUMAN,tr|H0YFV6|H0YFV6_HUMAN" 2 839.448 0.02 94508 5586 2 839.447621 420.7313 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 4.53 1521.7 - 1.29E+07 - - - -0.4491 - 1.223 0.015 - 198.7 1 2 0 -0.0004 7 0 0 0 1.74E+07 8.58E+08 - - - -0.2105 0.9999 221125_WJC_METTL3_EV_vs_WT_F07.05587.05587.3 0.000547 Sep-36 K.LGIHEDSQNR[166.11].K sp|P07900|HS90A_HUMAN 1 1177.5715 0.44 94509 5587 3 1177.571217 393.5311 Heat shock protein HSP 90-alpha OS=Homo sapiens OX=9606 GN=HSP90AA1 PE=1 SV=5 5.32 1521.7 - 9.26E+06 - - - -0.2565 - 1.904 0.401 - 95.3 1 2 0 -0.0003 10 0 0 0 2.19E+08 5.00E+08 - - - 4.8913 0.9998 221125_WJC_METTL3_EV_vs_WT_F07.05588.05588.2 0.000906 16-Nov K.K[136.11]SLESINSR[166.11].L "sp|P62888|RL30_HUMAN,tr|E5RJH3|E5RJH3_HUMAN,tr|E5RI99|E5RI99_HUMAN,tr|A0A0C4DH44|A0A0C4DH44_HUMAN" 4 1050.5788 1.16 94510 5588 2 1050.578712 526.2967 60S ribosomal protein L30 OS=Homo sapiens OX=9606 GN=RPL30 PE=1 SV=2 8.75 1521.7 - 6.43E+06 - - - -0.1247 - 2.104 0.364 - 423.9 1 2 0 -0.0001 9 0 0 0 9.13E+07 7.87E+07 - - - 3.8814 0.9999 221125_WJC_METTL3_EV_vs_WT_F07.05589.05589.2 1.81E-05 20-Dec K.TQETLSQAGQK[136.11].T "sp|O43399|TPD54_HUMAN,tr|A0A087WYR3|A0A087WYR3_HUMAN" 2 1197.6081 1.56 94511 5589 2 1197.607665 599.8113 Tumor protein D54 OS=Homo sapiens OX=9606 GN=TPD52L2 PE=1 SV=2 5.66 1521.8 - 6.05E+06 - - - -0.3474 - 2.398 0.571 - 584.4 1 2 0 -0.0004 11 0 0 0 1.25E+08 8.02E+07 - - - 5.6244 0.9996 221125_WJC_METTL3_EV_vs_WT_F07.05590.05590.2 0.611 16-Nov K.KSLESINSR.L "sp|P62888|RL30_HUMAN,tr|E5RJH3|E5RJH3_HUMAN,tr|E5RI99|E5RI99_HUMAN,tr|A0A0C4DH44|A0A0C4DH44_HUMAN" 4 1032.5564 1.16 94512 5590 2 1032.556094 517.2855 60S ribosomal protein L30 OS=Homo sapiens OX=9606 GN=RPL30 PE=1 SV=2 8.75 1521.8 - 5.70E+06 - - - -0.2702 - 2.098 0.295 - 451.7 1 2 0 -0.0003 9 0 0 0 9.13E+07 7.87E+07 - - - 3.3635 0.9371 221125_WJC_METTL3_EV_vs_WT_F07.05591.05591.3 0.00389 Sep-40 Y.SQLAHPIQQAK.A sp|O43615|TIM44_HUMAN 1 1219.6673 0.81 94513 5591 3 1219.667274 407.563 Mitochondrial import inner membrane translocase subunit TIM44 OS=Homo sapiens OX=9606 GN=TIMM44 PE=1 SV=2 8.49 1521.9 - 3.86E+06 - - - -0.0377 - 1.783 0.31 - 113.3 1 1 0 0 11 0 0 0 2.06E+07 2.53E+07 - - - 3.639 0.9495 221125_WJC_METTL3_EV_vs_WT_F07.05592.05592.3 0.00578 Nov-40 Y.SQLAHPIQQAK[136.11].A sp|O43615|TIM44_HUMAN 1 1227.6815 0.87 94514 5592 3 1227.682123 410.2344 Mitochondrial import inner membrane translocase subunit TIM44 OS=Homo sapiens OX=9606 GN=TIMM44 PE=1 SV=2 8.49 1521.9 - 3.03E+06 - - - 0.4912 - 2.076 0.287 - 132.9 1 1 0 0.0006 11 0 0 0 2.20E+07 2.54E+07 - - - 3.8147 0.9981 221125_WJC_METTL3_EV_vs_WT_F07.05598.05598.2 0.0206 18-Sep R.LQSEPESIR[166.11]K[136.11].W "sp|P09496|CLCA_HUMAN,tr|F8WF69|F8WF69_HUMAN" 2 1203.6578 0.53 94520 5598 2 1203.660125 602.8362 Clathrin light chain A OS=Homo sapiens OX=9606 GN=CLTA PE=1 SV=1 6.14 1522.3 - 863282 - - - 1.9142 - 1.45 0.326 - 282 1 2 0 0.0023 10 0 0 0 8.64E+06 1.63E+07 - - - 2.4853 0.9904 221125_WJC_METTL3_EV_vs_WT_F07.05599.05599.2 0.0842 18-Dec K.GK[136.11]DSLYAQGR[166.11].R sp|Q969Q0|RL36L_HUMAN 1 1111.5741 2.15 94521 5599 2 1111.572708 556.7943 60S ribosomal protein L36a-like OS=Homo sapiens OX=9606 GN=RPL36AL PE=1 SV=3 8.59 1522.4 - 632152 - - - -1.2451 - 2.018 0.241 - 404.9 1 2 1 -0.0014 10 0 0 0 1.41E+07 6.57E+06 - - - 2.7804 0.9932 221125_WJC_METTL3_EV_vs_WT_F07.05600.05600.2 0.144 22-Jul R.QQVAPTDDETGK.E "sp|Q13813|SPTN1_HUMAN,tr|A0A0D9SF54|A0A0D9SF54_HUMAN,tr|A0A0D9SGF6|A0A0D9SGF6_HUMAN" 3 1287.5943 1.12 94522 5600 2 1287.596532 644.8044 "Spectrin alpha chain, non-erythrocytic 1 OS=Homo sapiens OX=9606 GN=SPTAN1 PE=1 SV=3" 4.03 1522.5 - 302546 - - - 1.7537 - 1.405 0.196 - 181.6 1 2 0 0.0023 12 0 0 0 2.15E+06 1.92E+06 - - - 1.3826 0.9996 221125_WJC_METTL3_EV_vs_WT_F07.05603.05603.2 0.072 14-Sep K.TDSEKPFR.G "sp|Q9Y2W1|TR150_HUMAN,tr|A0A3B3ITZ9|A0A3B3ITZ9_HUMAN" 2 978.4771 2.68 94524 5603 2 978.477342 490.2458 Thyroid hormone receptor-associated protein 3 OS=Homo sapiens OX=9606 GN=THRAP3 PE=1 SV=2 5.74 1522.9 - 2.11E+07 - - - 0.2882 - 1.924 0.301 - 358.7 1 2 0 0.0003 8 0 0 0 2.87E+09 1.07E+09 - - - 3.2378 0.9999 221125_WJC_METTL3_EV_vs_WT_F07.05605.05605.3 4.34E-05 Oct-36 K.LGIHEDSQNR.K sp|P07900|HS90A_HUMAN 1 1167.5632 0.44 94526 5605 3 1167.562587 390.195 Heat shock protein HSP 90-alpha OS=Homo sapiens OX=9606 GN=HSP90AA1 PE=1 SV=5 5.32 1523 - 1.69E+07 - - - -0.567 - 1.875 0.436 - 142.5 1 2 0 -0.0007 10 0 0 0 2.17E+08 4.94E+08 - - - 5.2366 0.9999 221125_WJC_METTL3_EV_vs_WT_F07.05606.05606.2 6.44E-05 24-Dec K.EESAASGGAAYTK[136.11].R "sp|Q9Y2W1|TR150_HUMAN,tr|A0A3B3ITZ9|A0A3B3ITZ9_HUMAN" 2 1248.5714 3.06 94527 5606 2 1248.570659 625.293 Thyroid hormone receptor-associated protein 3 OS=Homo sapiens OX=9606 GN=THRAP3 PE=1 SV=2 4.53 1523 - 7.27E+06 - - - -0.5622 - 2.523 0.53 - 627.9 1 2 0 -0.0007 13 0 0 0 2.48E+09 8.09E+08 - - - 5.3306 0.9969 221125_WJC_METTL3_EV_vs_WT_F07.05610.05610.2 5.11 14-Aug K.KLQEQLEK.A "sp|Q9P2E9|RRBP1_HUMAN,tr|A0A087WU26|A0A087WU26_HUMAN,tr|A0A087WVV2|A0A087WVV2_HUMAN,tr|F8W7S5|F8W7S5_HUMAN" 4 1014.571 1.08 94531 5610 2 1014.571071 508.2928 Ribosome-binding protein 1 OS=Homo sapiens OX=9606 GN=RRBP1 PE=1 SV=5 6.14 1523.2 - 1.97E+06 - - - 0.1094 - 1.413 0.187 - 176.7 1 2 0 0.0001 8 0 0 0 1.78E+07 1.66E+07 - - - 1.4648 0.9983 221125_WJC_METTL3_EV_vs_WT_F07.05612.05612.2 0.0741 14-Aug R.RYEEQELK.E "sp|Q5T200|ZC3HD_HUMAN,tr|A0A7I2V4I5|A0A7I2V4I5_HUMAN" 2 1093.5404 1.86 94533 5612 2 1093.539649 547.7775 Zinc finger CCCH domain-containing protein 13 OS=Homo sapiens OX=9606 GN=ZC3H13 PE=1 SV=1 4.79 1523.4 - 1.49E+06 - - - -0.6758 - 1.743 0.169 - 267.7 1 2 0 -0.0007 8 0 0 0 2.23E+07 1.20E+07 - - - 1.9647 0.9935 221125_WJC_METTL3_EV_vs_WT_F07.05613.05613.2 8.97E-06 18-Oct L.NQEDNTNLAR[166.11].V "sp|O14744|ANM5_HUMAN,tr|C9JSX3|C9JSX3_HUMAN,tr|G3V2X6|G3V2X6_HUMAN,tr|G3V5L5|G3V5L5_HUMAN,tr|H0YJX6|H0YJX6_HUMAN" 5 1183.5457 3.52 94534 5613 2 1183.544546 592.7801 Protein arginine N-methyltransferase 5 OS=Homo sapiens OX=9606 GN=PRMT5 PE=1 SV=4 4.37 1523.4 - 1.43E+06 - - - -0.9733 - 2.331 0.542 - 506 1 1 0 -0.0012 10 0 0 0 9.88E+07 2.80E+07 - - - 5.4061 0.9995 221125_WJC_METTL3_EV_vs_WT_F07.05618.05618.3 0.00101 Oct-36 R.TAQEVETYR[166.11]R[166.11].S "sp|P17844|DDX5_HUMAN,tr|J3QR02|J3QR02_HUMAN,tr|A0A7I2V507|A0A7I2V507_HUMAN,tr|J3KTA4|J3KTA4_HUMAN,tr|J3KTQ4|J3KTQ4_HUMAN,tr|A0A7I2V2S0|A0A7I2V2S0_HUMAN,tr|J3QRQ7|J3QRQ7_HUMAN" 7 1271.6373 1.54 94537 5618 3 1271.635428 424.8864 Probable ATP-dependent RNA helicase DDX5 OS=Homo sapiens OX=9606 GN=DDX5 PE=1 SV=1 5.81 1524.1 - 6.52E+06 - - - -1.4753 - 2.143 0.287 - 174.7 1 2 0 -0.0019 10 0 0 0 4.41E+08 2.87E+08 - - - 3.9652 0.9986 221125_WJC_METTL3_EV_vs_WT_F07.05620.05620.3 0.0825 Dec-36 R.TAQEVETYRR.S "sp|P17844|DDX5_HUMAN,tr|J3QR02|J3QR02_HUMAN,tr|A0A7I2V507|A0A7I2V507_HUMAN,tr|J3KTA4|J3KTA4_HUMAN,tr|J3KTQ4|J3KTQ4_HUMAN,tr|A0A7I2V2S0|A0A7I2V2S0_HUMAN,tr|J3QRQ7|J3QRQ7_HUMAN" 7 1251.6208 1.54 94539 5620 3 1251.619935 418.2142 Probable ATP-dependent RNA helicase DDX5 OS=Homo sapiens OX=9606 GN=DDX5 PE=1 SV=1 5.81 1524.2 - 6.91E+06 - - - -0.6623 - 2.058 0.216 - 255.2 1 2 0 -0.0008 10 0 0 0 4.41E+08 2.87E+08 - - - 3.0557 0.8718 221125_WJC_METTL3_EV_vs_WT_F07.05621.05621.2 0.0668 16-Jun L.GIHEDSQNR.K sp|P07900|HS90A_HUMAN 1 1054.4792 0.36 94540 5621 2 1054.477464 528.2469 Heat shock protein HSP 90-alpha OS=Homo sapiens OX=9606 GN=HSP90AA1 PE=1 SV=5 5.32 1524.2 - 2.39E+06 - - - -1.6321 - 1.15 0.353 - 103.6 1 1 0 -0.0017 9 0 0 0 1.77E+07 4.92E+07 - - - 2.0521 0.9999 221125_WJC_METTL3_EV_vs_WT_F07.05625.05625.2 0.000201 13/20 R.TGPTQQQVEGR[166.11].L "sp|Q9BUT9|MCRI2_HUMAN,tr|I3L172|I3L172_HUMAN" 2 1209.5977 1.55 94544 5625 2 1209.597187 605.8061 MAPK regulated corepressor interacting protein 2 OS=Homo sapiens OX=9606 GN=MCRIP2 PE=1 SV=2 5.66 1524.6 - 1.07E+06 - - - -0.4522 - 2.638 0.428 - 825.1 1 2 0 -0.0005 11 0 0 0 7.87E+07 5.08E+07 - - - 4.8262 0.9993 221125_WJC_METTL3_EV_vs_WT_F07.05627.05627.2 0.00221 14-Oct R.QNEEELSR.L "sp|Q15643|TRIPB_HUMAN,tr|H0YJ97|H0YJ97_HUMAN" 2 1003.4571 0.42 94546 5627 2 1003.455893 502.7358 Thyroid receptor-interacting protein 11 OS=Homo sapiens OX=9606 GN=TRIP11 PE=1 SV=3 4.25 1524.9 - 621556 - - - -1.156 - 1.756 0.297 - 484 1 2 0 -0.0012 8 0 0 0 2.48E+06 5.86E+06 - - - 2.9324 0.9982 221125_WJC_METTL3_EV_vs_WT_F07.05632.05632.2 0.102 16-Nov R.KQEVTAIER.S "sp|Q9NRY5|F1142_HUMAN,tr|E7ESJ7|E7ESJ7_HUMAN" 2 1072.5877 1.27 94549 5632 2 1072.585965 537.3011 Protein FAM114A2 OS=Homo sapiens OX=9606 GN=FAM114A2 PE=1 SV=4 6.14 1525.4 - 4.60E+06 - - - -1.5924 - 2.161 0.139 - 523 1 2 0 -0.0017 9 0 0 0 5.84E+07 4.59E+07 - - - 2.2964 0.9992 221125_WJC_METTL3_EV_vs_WT_F07.05633.05633.2 1.6 16-Nov R.K[136.11]QEVTAIER[166.11].S "sp|Q9NRY5|F1142_HUMAN,tr|E7ESJ7|E7ESJ7_HUMAN" 2 1090.6101 1.27 94550 5633 2 1090.610712 546.3123 Protein FAM114A2 OS=Homo sapiens OX=9606 GN=FAM114A2 PE=1 SV=4 6.14 1525.4 - 3.89E+06 - - - 0.5217 - 2.209 0.179 - 496.8 1 2 0 0.0006 9 0 0 0 5.84E+07 4.59E+07 - - - 2.6558 0.9878 221125_WJC_METTL3_EV_vs_WT_F07.05635.05635.2 0.135 16-Aug K.GSIDEVDKR.V "sp|Q9UNM6|PSD13_HUMAN,tr|J3KNQ3|J3KNQ3_HUMAN,tr|A0A087WUL9|A0A087WUL9_HUMAN" 3 1017.5091 0.73 94551 5635 2 1017.506202 509.7618 26S proteasome non-ATPase regulatory subunit 13 OS=Homo sapiens OX=9606 GN=PSMD13 PE=1 SV=2 4.56 1525.6 - 2.51E+06 - - - -2.8363 - 1.539 0.158 - 208.6 1 2 0 -0.0029 9 0 0 0 1.68E+07 2.29E+07 - - - 1.4544 0.9997 221125_WJC_METTL3_EV_vs_WT_F07.05636.05636.2 0.0012 13/18 R.TAQEVETYR[166.11]R[166.11].S "sp|P17844|DDX5_HUMAN,tr|J3QR02|J3QR02_HUMAN,tr|A0A7I2V507|A0A7I2V507_HUMAN,tr|J3KTA4|J3KTA4_HUMAN,tr|J3KTQ4|J3KTQ4_HUMAN,tr|A0A7I2V2S0|A0A7I2V2S0_HUMAN,tr|J3QRQ7|J3QRQ7_HUMAN" 7 1271.6373 1.09 94552 5636 2 1271.635853 636.8259 Probable ATP-dependent RNA helicase DDX5 OS=Homo sapiens OX=9606 GN=DDX5 PE=1 SV=1 5.81 1525.7 - 2.00E+06 - - - -1.141 - 1.763 0.426 - 270.2 1 2 0 -0.0015 10 0 0 0 3.96E+07 3.64E+07 - - - 3.7697 0.9566 221125_WJC_METTL3_EV_vs_WT_F07.05644.05644.2 0.0425 14-Jul L.GNDFHTNK[136.11].R "sp|P08708|RS17_HUMAN,tr|H0YN73|H0YN73_HUMAN,tr|H3BNC9|H3BNC9_HUMAN,tr|A0A0J9YYC4|A0A0J9YYC4_HUMAN,tr|H0YN88|H0YN88_HUMAN,tr|A0A075B716|A0A075B716_HUMAN" 6 939.429 0.33 94558 5644 2 939.428313 470.7218 40S ribosomal protein S17 OS=Homo sapiens OX=9606 GN=RPS17 PE=1 SV=2 6.74 1526.6 - 1.47E+07 - - - -0.7249 - 1.317 0.383 - 74.8 1 1 0 -0.0007 8 0 0 0 4.86E+07 1.48E+08 - - - 2.7001 0.9945 221125_WJC_METTL3_EV_vs_WT_F07.05645.05645.3 0.0651 13/40 K.ATVEDEK[136.11]LQGK[136.11].L "sp|P11142|HSP7C_HUMAN,tr|E9PNE6|E9PNE6_HUMAN,tr|A8K7Q2|A8K7Q2_HUMAN,tr|E9PKE3|E9PKE3_HUMAN,tr|E9PM13|E9PM13_HUMAN,tr|E9PS65|E9PS65_HUMAN" 6 1232.6583 0.34 94559 5645 3 1232.655691 411.8934 Heat shock cognate 71 kDa protein OS=Homo sapiens OX=9606 GN=HSPA8 PE=1 SV=1 4.68 1526.6 - 6.21E+06 - - - -2.1425 - 2.391 0.239 - 287.7 1 2 1 -0.0026 11 0 0 0 1.27E+07 3.71E+07 - - - 3.6803 0.9947 221125_WJC_METTL3_EV_vs_WT_F07.05646.05646.3 1.17E-05 Oct-40 K.IK[136.11]QELGEESTR[166.11].L sp|Q5JSZ5|PRC2B_HUMAN 1 1306.6848 1.31 94560 5646 3 1306.677596 436.5689 Protein PRRC2B OS=Homo sapiens OX=9606 GN=PRRC2B PE=1 SV=2 4.79 1526.7 - 5.60E+06 - - - -5.4856 - 2.046 0.477 - 173.6 1 2 1 -0.0072 11 0 0 0 8.42E+07 6.42E+07 - - - 5.8898 0.9998 221125_WJC_METTL3_EV_vs_WT_F07.05647.05647.3 0.00108 Oct-36 R.VADNSFDAK[136.11]R[166.11].G "sp|Q14978|NOLC1_HUMAN,tr|A0A0A0MRM9|A0A0A0MRM9_HUMAN" 2 1139.569 0.001 94561 5647 3 1139.567698 380.8636 Nucleolar and coiled-body phosphoprotein 1 OS=Homo sapiens OX=9606 GN=NOLC1 PE=1 SV=2 5.93 1526.7 - 4.62E+06 - - - -1.1478 - 2.312 0.348 - 194.8 1 2 0 -0.0013 10 0 0 0 0.00E+00 4.25E+07 - - - 4.8672 0.9995 221125_WJC_METTL3_EV_vs_WT_F07.05648.05648.3 0.00452 Jul-48 K.EESAASGGAAYTK.R "sp|Q9Y2W1|TR150_HUMAN,tr|A0A3B3ITZ9|A0A3B3ITZ9_HUMAN" 2 1240.5572 10.86 94562 5648 3 1240.556911 414.5263 Thyroid hormone receptor-associated protein 3 OS=Homo sapiens OX=9606 GN=THRAP3 PE=1 SV=2 4.53 1526.7 - 3.56E+06 - - - -0.2015 - 1.54 0.368 - 71.7 1 2 0 -0.0002 13 0 0 0 6.67E+07 6.14E+06 - - - 3.8135 0.9921 221125_WJC_METTL3_EV_vs_WT_F07.05649.05649.2 0.58 12-Nov R.RIDQLNR.E "sp|Q16891|MIC60_HUMAN,tr|B9A067|B9A067_HUMAN,tr|C9J406|C9J406_HUMAN,tr|H7C463|H7C463_HUMAN" 4 913.5094 1.49 94563 5649 2 913.508481 457.762 MICOS complex subunit MIC60 OS=Homo sapiens OX=9606 GN=IMMT PE=1 SV=1 9.6 1526.9 - 2.16E+06 - - - -0.9655 - 1.789 0.001 - 425.6 1 2 0 -0.0009 7 0 0 0 1.04E+07 6.97E+06 - - - 0.8911 0.9999 221125_WJC_METTL3_EV_vs_WT_F07.05650.05650.2 7.63E-06 16-Dec K.YQASHPNLR.K "sp|O95721|SNP29_HUMAN,tr|C9JAF7|C9JAF7_HUMAN" 2 1084.5414 0.75 94564 5650 2 1084.54084 543.278 Synaptosomal-associated protein 29 OS=Homo sapiens OX=9606 GN=SNAP29 PE=1 SV=1 8.75 1526.9 - 2.05E+06 - - - -0.508 - 1.898 0.515 - 513.6 1 2 0 -0.0006 9 0 0 0 1.45E+07 1.93E+07 - - - 4.6985 0.9997 221125_WJC_METTL3_EV_vs_WT_F07.05652.05652.2 0.000659 22-Dec K.AESTESIGSSEK[136.11].T "sp|Q9BZI7|REN3B_HUMAN,tr|A0A1B0GVA2|A0A1B0GVA2_HUMAN" 2 1231.5659 0.74 94566 5652 2 1231.564143 616.7902 Regulator of nonsense transcripts 3B OS=Homo sapiens OX=9606 GN=UPF3B PE=1 SV=1 4.25 1527.2 - 1.74E+06 - - - -1.4599 - 1.996 0.426 - 504.2 1 2 0 -0.0018 12 0 0 0 8.33E+06 1.12E+07 - - - 4.0054 0.9484 221125_WJC_METTL3_EV_vs_WT_F07.05654.05654.2 0.482 14/20 K.IKQELGEESTR.L sp|Q5JSZ5|PRC2B_HUMAN 1 1288.6623 1.19 94568 5654 2 1288.669874 645.3384 Protein PRRC2B OS=Homo sapiens OX=9606 GN=PRRC2B PE=1 SV=2 4.79 1527.4 - 1.32E+06 - - - 5.8821 - 2.444 0.436 - 559.9 1 2 1 0.0076 11 0 0 0 1.41E+07 1.18E+07 - - - 4.6764 0.9945 221125_WJC_METTL3_EV_vs_WT_F07.05655.05655.2 4.83E-05 20-Nov K.IK[136.11]QELGEESTR[166.11].L sp|Q5JSZ5|PRC2B_HUMAN 1 1306.6848 1.19 94569 5655 2 1306.680848 654.3497 Protein PRRC2B OS=Homo sapiens OX=9606 GN=PRRC2B PE=1 SV=2 4.79 1527.6 - 1.10E+06 - - - -2.9969 - 2.34 0.5 - 276 1 2 1 -0.0039 11 0 0 0 1.41E+07 1.18E+07 - - - 5.0326 0.9747 221125_WJC_METTL3_EV_vs_WT_F07.05656.05656.2 0.0403 18-Sep R.NKETNTVLAR.L "sp|Q96D71|REPS1_HUMAN,tr|H0YDT0|H0YDT0_HUMAN,tr|H0YE89|H0YE89_HUMAN,tr|E9PMG1|E9PMG1_HUMAN" 4 1144.62 2.46 94570 5656 2 1144.620638 573.3173 RalBP1-associated Eps domain-containing protein 1 OS=Homo sapiens OX=9606 GN=REPS1 PE=1 SV=3 8.75 1527.7 - 452393 - - - 0.5259 - 1.378 0.246 - 240 1 2 1 0.0006 10 0 0 0 2.52E+06 1.03E+06 - - - 1.7528 0.9999 221125_WJC_METTL3_EV_vs_WT_F07.05660.05660.2 0.0318 16-Oct R.LGNDFHTNK.R "sp|P08708|RS17_HUMAN,tr|H0YN73|H0YN73_HUMAN,tr|H3BNC9|H3BNC9_HUMAN,tr|A0A0J9YYC4|A0A0J9YYC4_HUMAN,tr|H0YN88|H0YN88_HUMAN,tr|A0A075B716|A0A075B716_HUMAN" 6 1044.4989 0.84 94572 5660 2 1044.497985 523.2567 40S ribosomal protein S17 OS=Homo sapiens OX=9606 GN=RPS17 PE=1 SV=2 6.74 1528.1 - 1.55E+07 - - - -0.8358 - 2.379 0.441 - 287.9 1 2 0 -0.0009 9 0 0 0 1.01E+08 1.20E+08 - - - 4.8053 0.9877 221125_WJC_METTL3_EV_vs_WT_F07.05662.05662.2 0.118 14-Aug R.LSK[136.11]EEIER[166.11].M "sp|P0DMV8|HS71A_HUMAN,sp|P34931|HS71L_HUMAN,sp|P0DMV9|HS71B_HUMAN,tr|Q53FA3|Q53FA3_HUMAN,tr|V9GZ37|V9GZ37_HUMAN,tr|A0A0G2JIW1|A0A0G2JIW1_HUMAN" 6 1020.557 0.25 94574 5662 2 1020.555996 511.2858 Heat shock 70 kDa protein 1A OS=Homo sapiens OX=9606 GN=HSPA1A PE=1 SV=1 4.79 1528.2 - 1.15E+07 - - - -1.0279 - 1.784 0.225 - 260.5 1 2 1 -0.001 8 0 0 0 6.26E+07 2.47E+08 - - - 2.4483 1 221125_WJC_METTL3_EV_vs_WT_F07.05667.05667.2 0.00343 17/22 K.K[136.11]GPGLAVQSGDK[136.11].T sp|Q96PK6|RBM14_HUMAN 1 1171.6532 2.04 94579 5667 2 1171.651806 586.8339 RNA-binding protein 14 OS=Homo sapiens OX=9606 GN=RBM14 PE=1 SV=2 8.59 1528.4 - 3.33E+06 - - - -1.1787 - 3.048 0.561 - 892.4 1 2 0 -0.0014 12 0 0 0 4.79E+07 2.34E+07 - - - 6.1165 0.9946 221125_WJC_METTL3_EV_vs_WT_F07.05671.05671.2 0.00768 20-Sep K.ATVEDEK[136.11]LQGK[136.11].L "sp|P11142|HSP7C_HUMAN,tr|E9PNE6|E9PNE6_HUMAN,tr|A8K7Q2|A8K7Q2_HUMAN,tr|E9PKE3|E9PKE3_HUMAN,tr|E9PM13|E9PM13_HUMAN,tr|E9PS65|E9PS65_HUMAN" 6 1232.6583 0.22 94583 5671 2 1232.656692 617.3364 Heat shock cognate 71 kDa protein OS=Homo sapiens OX=9606 GN=HSPA8 PE=1 SV=1 4.68 1528.8 - 1.24E+06 - - - -1.3305 - 2.029 0.334 - 338.3 1 2 1 -0.0016 11 0 0 0 1.57E+06 7.12E+06 - - - 3.4215 0.9993 221125_WJC_METTL3_EV_vs_WT_F07.05672.05672.2 2.34E-05 14-Nov K.EHNVFQNK.L sp|Q86UP2|KTN1_HUMAN 1 1014.4883 1.18 94584 5672 2 1014.491669 508.2514 Kinectin OS=Homo sapiens OX=9606 GN=KTN1 PE=1 SV=1 6.85 1528.9 - 1.10E+06 - - - 3.3278 - 1.877 0.518 - 385.3 1 2 0 0.0034 8 0 0 0 2.51E+07 2.14E+07 - - - 4.765 0.9997 221125_WJC_METTL3_EV_vs_WT_F07.05673.05673.2 0.0104 14-Sep K.HELLNSTR.E "sp|P78347|GTF2I_HUMAN,tr|A0A494C0Q7|A0A494C0Q7_HUMAN,tr|A0A494C1K3|A0A494C1K3_HUMAN" 3 968.5039 0.49 94585 5673 2 968.503599 485.2592 General transcription factor II-I OS=Homo sapiens OX=9606 GN=GTF2I PE=1 SV=2 6.75 1529 - 1.06E+06 - - - -0.3552 - 1.759 0.364 - 288.8 1 2 0 -0.0003 8 0 0 0 1.72E+07 3.47E+07 - - - 3.4326 0.9994 221125_WJC_METTL3_EV_vs_WT_F07.05677.05677.2 0.00094 20-Oct K.STLPGSTTSNK.G sp|Q9UPQ9|TNR6B_HUMAN 1 1091.5459 1.51 94587 5677 2 1091.545648 546.7802 Trinucleotide repeat-containing gene 6B protein OS=Homo sapiens OX=9606 GN=TNRC6B PE=1 SV=4 8.47 1529.5 - 3.41E+06 - - - -0.2015 - 1.534 0.368 - 257.8 1 2 0 -0.0002 11 0 0 0 4.32E+07 2.86E+07 - - - 2.9165 0.8969 221125_WJC_METTL3_EV_vs_WT_F07.05678.05678.2 0.0192 14-Aug R.DTYKDSIK.A "sp|Q9HBM1|SPC25_HUMAN,tr|C9JW94|C9JW94_HUMAN" 2 968.4815 0.81 94588 5678 2 968.478295 485.248 Kinetochore protein Spc25 OS=Homo sapiens OX=9606 GN=SPC25 PE=1 SV=1 5.96 1529.6 - 2.84E+06 - - - -3.2845 - 1.261 0.286 - 182.5 1 2 1 -0.0032 8 0 0 0 5.34E+07 6.59E+07 - - - 1.8518 0.9998 221125_WJC_METTL3_EV_vs_WT_F07.05679.05679.2 6.61E-05 16-Aug K.SC[160.03]SPELQQK[136.11].F sp|P16152|CBR1_HUMAN 1 1083.511 1.19 94589 5679 2 1083.509656 542.7628 Carbonyl reductase [NADPH] 1 OS=Homo sapiens OX=9606 GN=CBR1 PE=1 SV=3 5.72 1529.6 - 6.15E+06 - - - -1.2487 - 1.784 0.558 - 263.6 1 2 0 -0.0014 9 0 0 0 5.89E+07 4.96E+07 - - - 4.8366 0.9967 221125_WJC_METTL3_EV_vs_WT_F07.05681.05681.2 0.000156 18-Sep K.ESTSC[160.03]PVVQK.R sp|Q9H8H0|NOL11_HUMAN 1 1133.5387 1.34 94591 5681 2 1133.533099 567.7766 Nucleolar protein 11 OS=Homo sapiens OX=9606 GN=NOL11 PE=1 SV=1 6.09 1529.8 - 1.89E+06 - - - -4.9182 - 1.914 0.457 - 354.1 1 2 0 -0.0056 10 0 0 0 3.64E+07 2.72E+07 - - - 4.2268 0.9999 221125_WJC_METTL3_EV_vs_WT_F07.05684.05684.2 0.00106 14/28 K.VNGDASPAAAESGAK[136.11].E sp|P29966|MARCS_HUMAN 1 1351.6459 0.68 94594 5684 2 1351.646455 676.8302 Myristoylated alanine-rich C-kinase substrate OS=Homo sapiens OX=9606 GN=MARCKS PE=1 SV=4 4.37 1530.1 - 985302 - - - 0.3936 - 2.678 0.552 - 461 1 2 0 0.0005 15 0 0 0 1.43E+07 2.09E+07 - - - 5.5397 1 221125_WJC_METTL3_EV_vs_WT_F07.05685.05685.2 2.24E-10 28-Dec K.VNGDASPAAAESGAK.E sp|P29966|MARCS_HUMAN 1 1343.6317 0.68 94595 5685 2 1343.631991 672.8231 Myristoylated alanine-rich C-kinase substrate OS=Homo sapiens OX=9606 GN=MARCKS PE=1 SV=4 4.37 1530.2 - 702562 - - - 0.1995 - 2.969 0.7 - 336.6 1 2 0 0.0003 15 0 0 0 1.41E+07 2.07E+07 - - - 6.8866 0.9998 221125_WJC_METTL3_EV_vs_WT_F07.05690.05690.2 0.000737 18-Aug K.ESTSC[160.03]PVVQK[136.11].R sp|Q9H8H0|NOL11_HUMAN 1 1141.5529 1.34 94598 5690 2 1141.552569 571.7837 Nucleolar protein 11 OS=Homo sapiens OX=9606 GN=NOL11 PE=1 SV=1 6.09 1530.7 - 3.02E+06 - - - -0.2672 - 1.86 0.49 - 289.1 1 2 0 -0.0003 10 0 0 0 3.64E+07 2.72E+07 - - - 4.3923 0.9958 221125_WJC_METTL3_EV_vs_WT_F07.05693.05693.3 0.175 Oct-36 K.QLIDKETNDR.K sp|P15924|DESP_HUMAN 1 1230.6204 3.21 94601 5693 3 1230.61878 411.2141 Desmoplakin OS=Homo sapiens OX=9606 GN=DSP PE=1 SV=3 4.56 1530.9 - 3.18E+06 - - - -1.3408 - 1.659 0.312 - 121.2 1 2 1 -0.0016 10 0 0 0 3.50E+07 1.09E+07 - - - 3.4964 0.9898 221125_WJC_METTL3_EV_vs_WT_F07.05701.05701.2 0.00403 18-Dec S.RVADNSFDAK.R "sp|Q14978|NOLC1_HUMAN,tr|A0A0A0MRM9|A0A0A0MRM9_HUMAN" 2 1121.5465 1.83 94608 5701 2 1121.546734 561.7805 Nucleolar and coiled-body phosphoprotein 1 OS=Homo sapiens OX=9606 GN=NOLC1 PE=1 SV=2 5.96 1531.8 - 482134 - - - 0.1765 - 2.226 0.413 - 542.2 1 1 0 0.0002 10 0 0 0 1.52E+07 8.29E+06 - - - 4.325 0.9999 221125_WJC_METTL3_EV_vs_WT_F07.05703.05703.3 9.32E-07 Nov-40 K.VPVHDVTDASK.V "sp|P21333|FLNA_HUMAN,tr|Q60FE5|Q60FE5_HUMAN" 2 1166.5932 1.07 94609 5703 3 1166.593852 389.8717 Filamin-A OS=Homo sapiens OX=9606 GN=FLNA PE=1 SV=4 5.21 1532 - 5.92E+06 - - - 0.6 - 2.293 0.438 - 220.2 1 2 0 0.0007 11 0 0 0 1.08E+08 1.01E+08 - - - 5.7806 0.9996 221125_WJC_METTL3_EV_vs_WT_F07.05704.05704.2 0.041 14-Aug R.HFDETVNR[166.11].Y "sp|P04843|RPN1_HUMAN,tr|B7Z4L4|B7Z4L4_HUMAN" 2 1026.4758 1.21 94610 5704 2 1026.474968 514.2452 Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit 1 OS=Homo sapiens OX=9606 GN=RPN1 PE=1 SV=1 5.32 1532 - 2.90E+06 - - - -0.8378 - 1.587 0.392 - 187.3 1 2 0 -0.0009 8 0 0 0 1.21E+08 1.00E+08 - - - 3.3289 0.9999 221125_WJC_METTL3_EV_vs_WT_F07.05705.05705.2 0.00016 18-Dec K.TPSSSSLSQR.V sp|Q9H0H5|RGAP1_HUMAN 1 1048.5149 1.58 94611 5705 2 1048.514684 525.2647 Rac GTPase-activating protein 1 OS=Homo sapiens OX=9606 GN=RACGAP1 PE=1 SV=1 9.41 1532.1 - 1.78E+06 - - - -0.2079 - 2.435 0.518 - 691.5 1 2 0 -0.0002 10 0 0 0 2.45E+07 1.55E+07 - - - 5.351 0.9997 221125_WJC_METTL3_EV_vs_WT_F07.05707.05707.2 5.66E-05 18-Dec K.TPSSSSLSQR[166.11].V sp|Q9H0H5|RGAP1_HUMAN 1 1058.5232 1.58 94613 5707 2 1058.520879 530.2689 Rac GTPase-activating protein 1 OS=Homo sapiens OX=9606 GN=RACGAP1 PE=1 SV=1 9.41 1532.3 - 1.16E+06 - - - -2.1662 - 2.245 0.461 - 726.7 1 2 0 -0.0023 10 0 0 0 2.45E+07 1.55E+07 - - - 4.7026 0.7906 221125_WJC_METTL3_EV_vs_WT_F07.05708.05708.3 2.11 Nov-36 R.QVSIEEGER[166.11]K[136.11].A "sp|P20340|RAB6A_HUMAN,sp|Q53S08|RAB6D_HUMAN" 2 1191.6214 1.41 94614 5708 3 1191.625891 398.2144 Ras-related protein Rab-6A OS=Homo sapiens OX=9606 GN=RAB6A PE=1 SV=3 4.79 1532.4 - 993621 - - - 3.7386 - 1.59 0.1 - 149.2 1 2 0 0.0045 10 0 0 0 8.51E+07 6.05E+07 - - - 1.008 1 221125_WJC_METTL3_EV_vs_WT_F07.05711.05711.2 3.38E-10 15/24 K.TSAGTTDPEEATR.L "sp|Q14244|MAP7_HUMAN,tr|A0A087WZ40|A0A087WZ40_HUMAN" 2 1334.595 1.14 94617 5711 2 1334.591519 668.3048 Ensconsin OS=Homo sapiens OX=9606 GN=MAP7 PE=1 SV=1 4.14 1532.8 - 457087 - - - -2.6105 - 2.646 0.611 - 563.2 1 2 0 -0.0035 13 0 0 0 2.67E+07 2.33E+07 - - - 6.0501 0.9992 221125_WJC_METTL3_EV_vs_WT_F07.05715.05715.2 0.0177 14-Oct R.HFDETVNR.Y "sp|P04843|RPN1_HUMAN,tr|B7Z4L4|B7Z4L4_HUMAN" 2 1016.4676 1.21 94619 5715 2 1016.468091 509.2411 Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit 1 OS=Homo sapiens OX=9606 GN=RPN1 PE=1 SV=1 5.32 1533.3 - 8.92E+06 - - - 0.5244 - 1.738 0.264 - 313.4 1 2 0 0.0005 8 0 0 0 1.21E+08 1.00E+08 - - - 2.6578 0.9994 221125_WJC_METTL3_EV_vs_WT_F07.05719.05719.2 0.00137 14-Sep K.SSFK[136.11]PYSK[136.11].G "sp|Q9H7S9|ZN703_HUMAN,sp|Q96F45|ZN503_HUMAN" 2 958.5095 1.21 94623 5719 2 958.510176 480.262 Zinc finger protein 703 OS=Homo sapiens OX=9606 GN=ZNF703 PE=1 SV=1 9.7 1533.5 - 2.09E+06 - - - 0.723 - 1.621 0.333 - 302.4 1 2 0 0.0007 8 0 0 0 2.30E+08 1.89E+08 - - - 2.9572 0.9987 221125_WJC_METTL3_EV_vs_WT_F07.05721.05721.2 0.00451 16-Aug K.DYAESVGR[166.11]K[136.11].V sp|Q9HCD5|NCOA5_HUMAN 1 1041.521 2.01 94625 5721 2 1041.523409 521.7678 Nuclear receptor coactivator 5 OS=Homo sapiens OX=9606 GN=NCOA5 PE=1 SV=2 6.07 1533.6 - 1.03E+06 - - - 2.3197 - 1.576 0.37 - 224.2 1 2 0 0.0024 9 0 0 0 1.60E+07 7.95E+06 - - - 3.0891 0.9944 221125_WJC_METTL3_EV_vs_WT_F07.05723.05723.2 0.0698 18-Nov R.QVSIEEGER[166.11]K[136.11].A "sp|P20340|RAB6A_HUMAN,sp|Q53S08|RAB6D_HUMAN" 2 1191.6214 4.19 94627 5723 2 1191.625051 596.818 Ras-related protein Rab-6A OS=Homo sapiens OX=9606 GN=RAB6A PE=1 SV=3 4.79 1533.9 - 491422 - - - 3.0337 - 1.869 0.194 - 536.2 1 2 0 0.0036 10 0 0 0 3.39E+07 8.08E+06 - - - 2.2184 0.9978 221125_WJC_METTL3_EV_vs_WT_F07.05724.05724.2 0.0101 18-Oct K.QLIDKETNDR.K sp|P15924|DESP_HUMAN 1 1230.6204 5.64 94628 5724 2 1230.620056 616.3175 Desmoplakin OS=Homo sapiens OX=9606 GN=DSP PE=1 SV=3 4.56 1534 - 481996 - - - -0.3039 - 1.962 0.429 - 486.1 1 2 1 -0.0004 10 0 0 0 5.37E+06 9.51E+05 - - - 4.0907 1 221125_WJC_METTL3_EV_vs_WT_F07.05725.05725.2 1.34E-08 24-Dec H.GSYGSGSSSGGYR.G sp|P04264|K2C1_HUMAN 1 1220.5058 3.04 94629 5725 2 1220.506849 611.2602 "Keratin, type II cytoskeletal 1 OS=Homo sapiens OX=9606 GN=KRT1 PE=1 SV=6" 8.59 1534.1 - 385395 - - - 0.8644 - 2.061 0.663 - 299.5 1 1 0 0.0011 13 0 0 0 6.92E+06 2.28E+06 - - - 5.7937 0.9993 221125_WJC_METTL3_EV_vs_WT_F07.05727.05727.2 0.000777 24-Jul K.IIQQEQDQESADK.S sp|O75665|OFD1_HUMAN 1 1530.7162 2.87 94631 5727 2 1530.717982 766.3654 Oral-facial-digital syndrome 1 protein OS=Homo sapiens OX=9606 GN=OFD1 PE=1 SV=1 3.92 1534.4 - 206105 - - - 1.1766 - 1.249 0.469 - 55.6 1 2 0 0.0018 13 0 0 0 3.14E+06 1.10E+06 - - - 3.0751 0.9999 221125_WJC_METTL3_EV_vs_WT_F07.05728.05728.2 3.58E-08 13/26 K.AVAGQQQASVTAGK[136.11].V "sp|Q15025|TNIP1_HUMAN,tr|E7EW15|E7EW15_HUMAN,tr|E7EMV7|E7EMV7_HUMAN,tr|A0A0A0MRZ4|A0A0A0MRZ4_HUMAN" 4 1322.7034 2.63 94632 5728 2 1322.70317 662.359 TNFAIP3-interacting protein 1 OS=Homo sapiens OX=9606 GN=TNIP1 PE=1 SV=2 8.8 1534.5 - 183752 - - - -0.1573 - 2.463 0.567 - 570.9 1 2 0 -0.0002 14 0 0 0 4.18E+06 1.59E+06 - - - 5.4908 0.9999 221125_WJC_METTL3_EV_vs_WT_F07.05733.05733.2 6.70E-06 20-Nov R.VGSTSENITQK[136.11].V "sp|O00571|DDX3X_HUMAN,sp|O15523|DDX3Y_HUMAN,tr|A0A2R8YFR4|A0A2R8YFR4_HUMAN,tr|A0A2R8YCW1|A0A2R8YCW1_HUMAN,tr|A0A2R8YDH3|A0A2R8YDH3_HUMAN,tr|A0A2R8YDT5|A0A2R8YDT5_HUMAN,tr|A0A2R8Y645|A0A2R8Y645_HUMAN,tr|A0A2R8YF78|A0A2R8YF78_HUMAN,tr|A0A0D9SFB3|A0A0D9SFB3_HUMAN,tr|A0A2R8YFS5|A0A2R8YFS5_HUMAN,tr|A0A0D9SF53|A0A0D9SF53_HUMAN,tr|A0A2R8Y5G6|A0A2R8Y5G6_HUMAN,tr|A0A2R8Y7T2|A0A2R8Y7T2_HUMAN,tr|A0A0D9SG12|A0A0D9SG12_HUMAN,tr|F6S8Q4|F6S8Q4_HUMAN,tr|A0A2U3TZJ9|A0A2U3TZJ9_HUMAN,tr|A0A2R8Y4A4|A0A2R8Y4A4_HUMAN" 17 1170.5972 1.15 94635 5733 2 1170.597874 586.3059 ATP-dependent RNA helicase DDX3X OS=Homo sapiens OX=9606 GN=DDX3X PE=1 SV=3 5.97 1535 - 1.14E+07 - - - 0.592 - 2.606 0.55 - 590.6 1 2 0 0.0007 11 0 0 0 1.98E+08 1.72E+08 - - - 5.6942 1 221125_WJC_METTL3_EV_vs_WT_F07.05735.05735.2 6.17E-07 13/22 R.ASTALSNEQQAR.R sp|P12270|TPR_HUMAN 1 1274.6215 2.27 94637 5735 2 1274.622615 638.318 Nucleoprotein TPR OS=Homo sapiens OX=9606 GN=TPR PE=1 SV=3 6.05 1535.1 - 7.65E+06 - - - 0.881 - 2.584 0.599 - 610.2 1 2 0 0.0011 12 0 0 0 9.34E+07 4.11E+07 - - - 5.9627 0.9976 221125_WJC_METTL3_EV_vs_WT_F07.05738.05738.2 0.0274 14-Aug R.KDEPDAFK.E sp|P13674|P4HA1_HUMAN 1 948.4553 0.74 94640 5738 2 948.456376 475.2349 Prolyl 4-hydroxylase subunit alpha-1 OS=Homo sapiens OX=9606 GN=P4HA1 PE=1 SV=2 4.56 1535.2 - 2.78E+06 - - - 1.1745 - 1.551 0.211 - 179.4 1 2 0 0.0011 8 0 0 0 3.71E+07 5.03E+07 - - - 1.9228 0.9928 221125_WJC_METTL3_EV_vs_WT_F07.05739.05739.3 0.164 Nov-36 R.LTQEPESIRK.W "sp|P09497|CLCB_HUMAN,tr|H0Y9Q6|H0Y9Q6_HUMAN" 2 1199.651 0.74 94641 5739 3 1199.651843 400.8909 Clathrin light chain B OS=Homo sapiens OX=9606 GN=CLTB PE=1 SV=1 6.14 1535.3 - 2.73E+06 - - - 0.7019 - 1.827 0.153 - 152.3 1 2 0 0.0008 10 0 0 0 1.78E+07 2.42E+07 - - - 2.0056 0.9999 221125_WJC_METTL3_EV_vs_WT_F07.05741.05741.3 0.19 14/52 R.ITPPAAKPGSPQAK.S "sp|P35658|NU214_HUMAN,tr|A0A0A0MSW3|A0A0A0MSW3_HUMAN,tr|A0A494BZU9|A0A494BZU9_HUMAN,tr|A0A494C1F2|A0A494C1F2_HUMAN" 4 1361.7667 2.13 94643 5741 3 1361.7676 454.9295 Nuclear pore complex protein Nup214 OS=Homo sapiens OX=9606 GN=NUP214 PE=1 SV=2 10 1535.4 - 1.88E+06 - - - 0.6609 - 2.487 0.352 - 249.4 1 2 0 0.0009 14 0 0 0 4.60E+07 2.16E+07 - - - 4.8854 1 221125_WJC_METTL3_EV_vs_WT_F07.05742.05742.2 3.98E-07 15/24 K.TSAGTTDPEEATR[166.11].L "sp|Q14244|MAP7_HUMAN,tr|A0A087WZ40|A0A087WZ40_HUMAN" 2 1344.6033 1.14 94644 5742 2 1344.60643 673.3089 Ensconsin OS=Homo sapiens OX=9606 GN=MAP7 PE=1 SV=1 4.14 1535.6 - 1.33E+06 - - - 2.3479 - 2.951 0.634 - 612.9 1 2 0 0.0032 13 0 0 0 2.67E+07 2.33E+07 - - - 6.5001 0.9993 221125_WJC_METTL3_EV_vs_WT_F07.05745.05745.2 1.34E-05 20-Dec R.AQEAGLQQEQR.K "sp|Q8N5A5|ZGPAT_HUMAN,tr|V9GY48|V9GY48_HUMAN" 2 1256.6109 1.73 94647 5745 2 1256.612532 629.3127 Zinc finger CCCH-type with G patch domain-containing protein OS=Homo sapiens OX=9606 GN=ZGPAT PE=1 SV=3 4.53 1535.9 - 733511 - - - 1.2764 - 2.589 0.2 - 700.1 1 2 0 0.0016 11 0 0 0 1.83E+07 1.05E+07 - - - 3.0911 0.9173 221125_WJC_METTL3_EV_vs_WT_F07.05749.05749.2 0.108 18-Sep R.LK[136.11]EEGNEQFK[136.11].K "sp|Q99614|TTC1_HUMAN,tr|A0A804HKC5|A0A804HKC5_HUMAN,tr|A0A804HHT7|A0A804HHT7_HUMAN,tr|A0A804HIB8|A0A804HIB8_HUMAN,tr|A0A804HKI4|A0A804HKI4_HUMAN" 5 1236.6321 0.85 94650 5749 2 1236.636258 619.3233 Tetratricopeptide repeat protein 1 OS=Homo sapiens OX=9606 GN=TTC1 PE=1 SV=1 4.79 1536.5 - 684246 - - - 3.3486 - 1.797 0.194 - 159.8 1 2 1 0.0041 10 0 0 0 3.38E+06 3.96E+06 - - - 2.1086 0.9996 221125_WJC_METTL3_EV_vs_WT_F07.05751.05751.3 0.00228 13/36 K.VQVSYK[136.11]GETK[136.11].A "sp|P0DMV8|HS71A_HUMAN,sp|P0DMV9|HS71B_HUMAN,tr|A0A0G2JIW1|A0A0G2JIW1_HUMAN" 3 1153.6314 0.08 94651 5751 3 1153.631197 385.5511 Heat shock 70 kDa protein 1A OS=Homo sapiens OX=9606 GN=HSPA1A PE=1 SV=1 8.47 1536.7 - 1.16E+08 - - - -0.1664 - 2.27 0.397 - 318.5 1 2 1 -0.0002 10 0 0 0 7.40E+07 8.85E+08 - - - 5.3602 0.9963 221125_WJC_METTL3_EV_vs_WT_F07.05752.05752.2 0.163 18-Nov K.VQVSYK[136.11]GETK[136.11].A "sp|P0DMV8|HS71A_HUMAN,sp|P0DMV9|HS71B_HUMAN,tr|A0A0G2JIW1|A0A0G2JIW1_HUMAN" 3 1153.6314 0.11 94652 5752 2 1153.631616 577.823 Heat shock 70 kDa protein 1A OS=Homo sapiens OX=9606 GN=HSPA1A PE=1 SV=1 8.47 1536.7 - 1.45E+07 - - - 0.1968 - 2.092 0.323 - 474.8 1 2 1 0.0002 10 0 0 0 1.53E+07 1.38E+08 - - - 3.4869 0.9849 221125_WJC_METTL3_EV_vs_WT_F07.05753.05753.3 0.00944 Sep-36 K.VQVSYKGETK.A "sp|P0DMV8|HS71A_HUMAN,sp|P0DMV9|HS71B_HUMAN,tr|A0A0G2JIW1|A0A0G2JIW1_HUMAN" 3 1137.603 0.08 94653 5753 3 1137.604403 380.2083 Heat shock 70 kDa protein 1A OS=Homo sapiens OX=9606 GN=HSPA1A PE=1 SV=1 8.47 1536.7 - 7.44E+06 - - - 1.243 - 1.918 0.197 - 126.3 1 2 1 0.0014 10 0 0 0 7.40E+07 8.85E+08 - - - 2.638 0.9993 221125_WJC_METTL3_EV_vs_WT_F07.05756.05756.3 0.00106 Sep-36 K.QVEDEKNSFR.E sp|P35579|MYH9_HUMAN 1 1250.5891 0.16 94656 5756 3 1250.58939 417.8703 Myosin-9 OS=Homo sapiens OX=9606 GN=MYH9 PE=1 SV=4 4.68 1536.9 - 2.96E+06 - - - 0.2087 - 1.798 0.405 - 147.6 1 2 1 0.0003 10 0 0 0 1.16E+07 7.42E+07 - - - 4.7686 0.9997 221125_WJC_METTL3_EV_vs_WT_F07.05759.05759.2 0.0158 15/20 R.AQEAGLQQEQR[166.11].K "sp|Q8N5A5|ZGPAT_HUMAN,tr|V9GY48|V9GY48_HUMAN" 2 1266.6192 1.73 94659 5759 2 1266.619483 634.3169 Zinc finger CCCH-type with G patch domain-containing protein OS=Homo sapiens OX=9606 GN=ZGPAT PE=1 SV=3 4.53 1537.1 - 1.43E+06 - - - 0.225 - 2.812 0.25 - 1168.6 1 2 0 0.0003 11 0 0 0 1.83E+07 1.05E+07 - - - 3.6843 0.9945 221125_WJC_METTL3_EV_vs_WT_F07.05760.05760.2 0.345 12-Apr R.FHDFDHR.D "sp|Q14151|SAFB2_HUMAN,sp|Q15424|SAFB1_HUMAN,tr|K7EII0|K7EII0_HUMAN" 3 972.4202 1.32 94660 5760 2 972.419882 487.2174 Scaffold attachment factor B2 OS=Homo sapiens OX=9606 GN=SAFB2 PE=1 SV=1 5.98 1537.2 - 1.38E+06 - - - -0.3414 - 1.111 0.225 - 82.5 1 2 0 -0.0003 7 0 0 0 8.94E+06 6.75E+06 - - - 1.0363 0.9977 221125_WJC_METTL3_EV_vs_WT_F07.05769.05769.2 0.0331 16-Sep R.DK[136.11]LSGEYEK[136.11].F "sp|P34932|HSP74_HUMAN,tr|A0A087WYC1|A0A087WYC1_HUMAN" 2 1083.5419 0.12 94667 5769 2 1083.541776 542.7782 Heat shock 70 kDa protein 4 OS=Homo sapiens OX=9606 GN=HSPA4 PE=1 SV=4 4.68 1538.3 - 1.93E+07 - - - -0.1191 - 1.806 0.448 - 268.1 1 2 1 -0.0001 9 0 0 0 1.83E+07 1.57E+08 - - - 4.06 0.9997 221125_WJC_METTL3_EV_vs_WT_F07.05771.05771.3 0.000145 Sep-36 K.QSQHMTEVVR.R "sp|P04637|P53_HUMAN,tr|E7ESS1|E7ESS1_HUMAN,tr|J3KP33|J3KP33_HUMAN,tr|E9PFT5|E9PFT5_HUMAN,tr|A0A087X1Q1|A0A087X1Q1_HUMAN,tr|A0A0U1RQC9|A0A0U1RQC9_HUMAN,tr|A0A087WT22|A0A087WT22_HUMAN,tr|A0A087WXZ1|A0A087WXZ1_HUMAN,tr|E7EQX7|E7EQX7_HUMAN" 9 1213.5874 1.08 94669 5771 3 1213.586934 405.5364 Cellular tumor antigen p53 OS=Homo sapiens OX=9606 GN=TP53 PE=1 SV=4 6.75 1538.4 - 9.81E+06 - - - -0.3469 - 1.958 0.335 - 189.7 1 2 0 -0.0004 10 0 0 0 6.26E+07 5.81E+07 - - - 4.2371 0.9999 221125_WJC_METTL3_EV_vs_WT_F07.05774.05774.2 6.00E-06 13/22 K.QPTPPSEAAASK.K sp|Q86UP2|KTN1_HUMAN 1 1182.5881 1.43 94672 5774 2 1182.587335 592.3013 Kinectin OS=Homo sapiens OX=9606 GN=KTN1 PE=1 SV=1 6 1538.5 - 3.39E+06 - - - -0.619 - 2.142 0.494 - 560.3 1 2 0 -0.0007 12 0 0 0 2.95E+07 2.06E+07 - - - 4.6937 0.9886 221125_WJC_METTL3_EV_vs_WT_F07.05775.05775.2 5.06E-05 16-Aug M.FQYDSTHGK[136.11].F sp|P04406|G3P_HUMAN 1 1089.4971 1.16 94673 5775 2 1089.496536 545.7558 Glyceraldehyde-3-phosphate dehydrogenase OS=Homo sapiens OX=9606 GN=GAPDH PE=1 SV=3 6.74 1538.6 - 2.59E+06 - - - -0.4929 - 1.537 0.526 - 194 1 1 0 -0.0005 9 0 0 0 1.91E+07 1.64E+07 - - - 4.1694 0.9998 221125_WJC_METTL3_EV_vs_WT_F07.05778.05778.2 5.19E-05 18-Nov K.QSQHMTEVVR.R "sp|P04637|P53_HUMAN,tr|E7ESS1|E7ESS1_HUMAN,tr|J3KP33|J3KP33_HUMAN,tr|E9PFT5|E9PFT5_HUMAN,tr|A0A087X1Q1|A0A087X1Q1_HUMAN,tr|A0A0U1RQC9|A0A0U1RQC9_HUMAN,tr|A0A087WT22|A0A087WT22_HUMAN,tr|A0A087WXZ1|A0A087WXZ1_HUMAN,tr|E7EQX7|E7EQX7_HUMAN" 9 1213.5874 1.01 94676 5778 2 1213.587854 607.801 Cellular tumor antigen p53 OS=Homo sapiens OX=9606 GN=TP53 PE=1 SV=4 6.75 1538.8 - 1.05E+06 - - - 0.4112 - 1.963 0.41 - 323.9 1 2 0 0.0005 10 0 0 0 7.59E+06 7.54E+06 - - - 3.9518 1 221125_WJC_METTL3_EV_vs_WT_F07.05779.05779.2 8.52E-10 13/24 K.VGDSDGSSNLDGK.K sp|Q9UKJ3|GPTC8_HUMAN 1 1249.5422 1.09 94677 5779 2 1249.541496 625.7784 G patch domain-containing protein 8 OS=Homo sapiens OX=9606 GN=GPATCH8 PE=1 SV=2 3.93 1539 - 887099 - - - -0.5946 - 2.924 0.638 - 551 1 2 0 -0.0007 13 0 0 0 5.74E+06 5.25E+06 - - - 6.5068 0.9917 221125_WJC_METTL3_EV_vs_WT_F07.05781.05781.2 0.0914 24-Jul K.IEEAYGDVSGLC[160.03]R[166.11].R "sp|Q16720|AT2B3_HUMAN,tr|A0A804HKZ0|A0A804HKZ0_HUMAN" 2 1477.6747 0.001 94679 5781 2 1477.669594 739.8446 Plasma membrane calcium-transporting ATPase 3 OS=Homo sapiens OX=9606 GN=ATP2B3 PE=1 SV=3 4.14 1539.2 - 708992 - - - -3.4311 - 1.562 0.26 - 111.5 1 2 0 -0.0051 13 0 0 0 0.00E+00 4.61E+07 - - - 2.1044 0.9998 221125_WJC_METTL3_EV_vs_WT_F07.05782.05782.2 5.07E-07 13/24 K.C[160.03]ASQSGMTAYGTR[166.11].R "sp|Q99439|CNN2_HUMAN,tr|H3BVI6|H3BVI6_HUMAN,tr|B4DDF4|B4DDF4_HUMAN,tr|H3BQH0|H3BQH0_HUMAN,tr|A0A087X271|A0A087X271_HUMAN,tr|U3KPS3|U3KPS3_HUMAN,tr|A0A087X1X5|A0A087X1X5_HUMAN,tr|B4DUT8|B4DUT8_HUMAN" 8 1398.5896 0.36 94680 5782 2 1398.586943 700.3021 Calponin-2 OS=Homo sapiens OX=9606 GN=CNN2 PE=1 SV=4 8.22 1539.4 - 588718 - - - -1.8669 - 1.889 0.664 - 324.2 1 2 0 -0.0026 13 0 0 0 1.50E+06 4.15E+06 - - - 5.5769 0.9274 221125_WJC_METTL3_EV_vs_WT_F07.05784.05784.2 0.198 24-Jun K.LEEAEKAADESER[166.11].G "sp|P67936|TPM4_HUMAN,sp|P09493|TPM1_HUMAN,sp|P06753|TPM3_HUMAN,sp|P07951|TPM2_HUMAN,tr|A0A0S2Z4G6|A0A0S2Z4G6_HUMAN,tr|A0A494C0G0|A0A494C0G0_HUMAN,tr|A7XZE4|A7XZE4_HUMAN,tr|A0A2R8Y5V9|A0A2R8Y5V9_HUMAN,tr|F5H7S3|F5H7S3_HUMAN,tr|H0YKX5|H0YKX5_HUMAN,tr|Q6ZN40|Q6ZN40_HUMAN,tr|A0A2R8YEU4|A0A2R8YEU4_HUMAN,tr|A0A2R8YGX3|A0A2R8YGX3_HUMAN,tr|A0A2R2Y2Q3|A0A2R2Y2Q3_HUMAN,tr|A0A087WWU8|A0A087WWU8_HUMAN,tr|H0YKJ4|H0YKJ4_HUMAN,tr|H0YK48|H0YK48_HUMAN,tr|H0YL80|H0YL80_HUMAN,tr|K7ENT6|K7ENT6_HUMAN,tr|J3KN67|J3KN67_HUMAN,tr|A0A494C0P6|A0A494C0P6_HUMAN,tr|D6R904|D6R904_HUMAN,tr|A0A2R8YH90|A0A2R8YH90_HUMAN,tr|B7Z596|B7Z596_HUMAN,tr|H0YKP3|H0YKP3_HUMAN,tr|A0A494BZZ2|A0A494BZZ2_HUMAN,tr|Q5TCU3|Q5TCU3_HUMAN,tr|A0A2R8YE05|A0A2R8YE05_HUMAN,tr|A0A2R8YHD2|A0A2R8YHD2_HUMAN,tr|H7BYY1|H7BYY1_HUMAN" 30 1485.6823 - 94682 5784 2 1485.685794 743.8484 Tropomyosin alpha-4 chain OS=Homo sapiens OX=9606 GN=TPM4 PE=1 SV=3 4.14 1539.6 - 342338 - - - 2.3848 - 1.369 0.247 - 82.1 1 2 1 0.0035 13 0 0 0 - - - - - 1.6703 0.9987 221125_WJC_METTL3_EV_vs_WT_F07.05788.05788.3 0.1 Nov-36 R.AAQDRDQIYR.R "sp|P62995|TRA2B_HUMAN,tr|H7C2L4|H7C2L4_HUMAN" 2 1234.6054 1.48 94684 5788 3 1234.604747 412.5424 Transformer-2 protein homolog beta OS=Homo sapiens OX=9606 GN=TRA2B PE=1 SV=1 6 1540 - 1.78E+07 - - - -0.5678 - 2.192 0.309 - 292.5 1 2 1 -0.0007 10 0 0 0 4.21E+08 2.84E+08 - - - 4.2769 0.9507 221125_WJC_METTL3_EV_vs_WT_F07.05790.05790.2 0.00374 12-Jun V.HDDLYDK[136.11].K sp|Q2NL82|TSR1_HUMAN 1 912.4069 0.04 94686 5790 2 912.407298 457.2107 Pre-rRNA-processing protein TSR1 homolog OS=Homo sapiens OX=9606 GN=TSR1 PE=1 SV=1 4.41 1540.1 - 9.76E+07 - - - 0.479 - 1.346 0.351 - 156.3 1 1 0 0.0004 7 0 0 0 6.73E+07 1.82E+09 - - - 2.5748 0.9997 221125_WJC_METTL3_EV_vs_WT_F07.05791.05791.3 0.0065 14/36 K.VQVEYK[136.11]GETK[136.11].T "sp|P54652|HSP72_HUMAN,sp|P11142|HSP7C_HUMAN,tr|E9PQQ4|E9PQQ4_HUMAN,tr|E9PKE3|E9PKE3_HUMAN,tr|E9PN89|E9PN89_HUMAN,tr|E9PLF4|E9PLF4_HUMAN,tr|E9PK54|E9PK54_HUMAN,tr|E9PN25|E9PN25_HUMAN,tr|E9PPY6|E9PPY6_HUMAN,tr|E9PQK7|E9PQK7_HUMAN" 10 1195.642 0.15 94687 5791 3 1195.642269 399.5546 Heat shock-related 70 kDa protein 2 OS=Homo sapiens OX=9606 GN=HSPA2 PE=1 SV=1 6.11 1540.1 - 9.07E+06 - - - 0.2643 - 2.383 0.399 - 350.2 1 2 1 0.0003 10 0 0 0 5.62E+08 3.86E+09 - - - 5.5244 0.9998 221125_WJC_METTL3_EV_vs_WT_F07.05792.05792.3 0.000764 Oct-44 K.LVDQSGPPHEPK[136.11].F "sp|P55265|DSRAD_HUMAN,tr|A0A3B3IRQ9|A0A3B3IRQ9_HUMAN,tr|A0A3B3ISU1|A0A3B3ISU1_HUMAN,tr|A0A7P0Z4K3|A0A7P0Z4K3_HUMAN,tr|A0A3B3ISX1|A0A3B3ISX1_HUMAN,tr|A0A7P0Z4F9|A0A7P0Z4F9_HUMAN" 6 1310.671 1.5 94688 5792 3 1310.671151 437.8976 Double-stranded RNA-specific adenosine deaminase OS=Homo sapiens OX=9606 GN=ADAR PE=1 SV=4 5.32 1540.2 - 6.70E+06 - - - 0.1038 - 1.922 0.389 - 117.2 1 2 0 0.0001 12 0 0 0 1.63E+08 1.09E+08 - - - 4.688 0.9856 221125_WJC_METTL3_EV_vs_WT_F07.05793.05793.2 0.0043 16-Aug R.EQEVAELK[136.11]K[136.11].A sp|P35580|MYH10_HUMAN 1 1088.6048 0.9 94689 5793 2 1088.604092 545.3097 Myosin-10 OS=Homo sapiens OX=9606 GN=MYH10 PE=1 SV=3 4.79 1540.2 - 4.09E+06 - - - -0.6871 - 1.55 0.033 - 213.2 2 2 0 -0.0007 9 0 0 0 2.40E+07 2.65E+07 - - - 0.4179 0.9901 221125_WJC_METTL3_EV_vs_WT_F07.05796.05796.2 0.00867 16-Sep R.DKLSGEYEK.F "sp|P34932|HSP74_HUMAN,tr|A0A087WYC1|A0A087WYC1_HUMAN" 2 1067.5135 0.12 94692 5796 2 1067.514143 534.764 Heat shock 70 kDa protein 4 OS=Homo sapiens OX=9606 GN=HSPA4 PE=1 SV=4 4.68 1540.4 - 2.86E+06 - - - 0.5977 - 1.557 0.306 - 180.7 1 2 1 0.0006 9 0 0 0 1.97E+07 1.60E+08 - - - 2.5818 0.9947 221125_WJC_METTL3_EV_vs_WT_F07.05800.05800.2 0.0687 18-Dec R.AAQDR[166.11]DQIYR[166.11].R "sp|P62995|TRA2B_HUMAN,tr|H7C2L4|H7C2L4_HUMAN" 2 1254.622 1.46 94696 5800 2 1254.620882 628.3183 Transformer-2 protein homolog beta OS=Homo sapiens OX=9606 GN=TRA2B PE=1 SV=1 6 1540.8 - 1.63E+06 - - - -0.8815 - 1.935 0.316 - 272.7 1 2 1 -0.0011 10 0 0 0 7.14E+07 4.90E+07 - - - 3.2172 0.9981 221125_WJC_METTL3_EV_vs_WT_F07.05802.05802.2 0.000281 18-Dec K.VQVEYK[136.11]GETK[136.11].T "sp|P54652|HSP72_HUMAN,sp|P11142|HSP7C_HUMAN,tr|E9PQQ4|E9PQQ4_HUMAN,tr|E9PKE3|E9PKE3_HUMAN,tr|E9PN89|E9PN89_HUMAN,tr|E9PLF4|E9PLF4_HUMAN,tr|E9PK54|E9PK54_HUMAN,tr|E9PN25|E9PN25_HUMAN,tr|E9PPY6|E9PPY6_HUMAN,tr|E9PQK7|E9PQK7_HUMAN" 10 1195.642 0.15 94698 5802 2 1195.641759 598.8283 Heat shock-related 70 kDa protein 2 OS=Homo sapiens OX=9606 GN=HSPA2 PE=1 SV=1 6.11 1541 - 1.21E+06 - - - -0.1623 - 2.077 0.433 - 595.6 1 2 1 -0.0002 10 0 0 0 1.00E+08 6.53E+08 - - - 4.2793 0.9942 221125_WJC_METTL3_EV_vs_WT_F07.05806.05806.2 6.27E-06 13/24 A.LTQSVGGDSSADR[166.11].L "sp|Q86U44|MTA70_HUMAN,tr|H0YFV6|H0YFV6_HUMAN" 2 1301.6087 0.1 94700 5806 2 1301.607489 651.8116 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 4.21 1541.6 - 2.18E+07 - - - -0.9242 - 2.447 0.581 - 523.2 1 1 0 -0.0012 13 0 0 0 1.33E+07 1.39E+08 - - - 5.6286 0.9663 221125_WJC_METTL3_EV_vs_WT_F07.05807.05807.3 0.146 Aug-36 K.VQVEYKGETK.T "sp|P54652|HSP72_HUMAN,sp|P11142|HSP7C_HUMAN,tr|E9PQQ4|E9PQQ4_HUMAN,tr|E9PKE3|E9PKE3_HUMAN,tr|E9PN89|E9PN89_HUMAN,tr|E9PLF4|E9PLF4_HUMAN,tr|E9PK54|E9PK54_HUMAN,tr|E9PN25|E9PN25_HUMAN,tr|E9PPY6|E9PPY6_HUMAN,tr|E9PQK7|E9PQK7_HUMAN" 10 1179.6136 0.15 94701 5807 3 1179.612437 394.2118 Heat shock-related 70 kDa protein 2 OS=Homo sapiens OX=9606 GN=HSPA2 PE=1 SV=1 6.11 1541.6 - 1.62E+07 - - - -0.9461 - 1.678 0.173 - 102.5 1 2 1 -0.0011 10 0 0 0 5.65E+08 3.86E+09 - - - 1.9801 0.9416 221125_WJC_METTL3_EV_vs_WT_F07.05808.05808.3 0.196 Oct-40 R.ALSQGVESVK[136.11]K[136.11].E "sp|O43615|TIM44_HUMAN,tr|M0QXU7|M0QXU7_HUMAN" 2 1160.6736 1.01 94702 5808 3 1160.672175 387.8985 Mitochondrial import inner membrane translocase subunit TIM44 OS=Homo sapiens OX=9606 GN=TIMM44 PE=1 SV=2 8.64 1541.6 - 1.51E+07 - - - -1.2174 - 1.389 0.121 - 96 1 2 0 -0.0014 11 0 0 0 2.45E+08 2.44E+08 - - - 0.8221 0.9995 221125_WJC_METTL3_EV_vs_WT_F07.05809.05809.3 8.44E-05 15/44 R.QAGEVTYADAHK.G "sp|Q08170|SRSF4_HUMAN,sp|Q13247|SRSF6_HUMAN,tr|A0A590UK80|A0A590UK80_HUMAN,tr|A0A590UJK4|A0A590UJK4_HUMAN,tr|A0A590UJP7|A0A590UJP7_HUMAN,tr|A0A0D9SEM4|A0A0D9SEM4_HUMAN,tr|A0A590UK01|A0A590UK01_HUMAN" 7 1288.6048 0.17 94703 5809 3 1288.603546 430.5422 Serine\arginine-rich splicing factor 4 OS=Homo sapiens OX=9606 GN=SRSF4 PE=1 SV=2 5.32 1541.7 - 9.71E+06 - - - -0.9576 - 2.186 0.278 - 264.1 1 2 0 -0.0012 12 0 0 0 1.09E+08 6.57E+08 - - - 3.8069 0.9758 221125_WJC_METTL3_EV_vs_WT_F07.05810.05810.2 7.98E-05 18-Oct L.QQSISDAEQR.G sp|P04264|K2C1_HUMAN 1 1160.5422 21.44 94704 5810 2 1160.540397 581.2784 "Keratin, type II cytoskeletal 1 OS=Homo sapiens OX=9606 GN=KRT1 PE=1 SV=6" 4.37 1541.7 - 5.50E+06 - - - -1.5355 - 1.743 0.427 - 454.9 1 1 0 -0.0018 10 0 0 0 3.63E+07 1.69E+06 - - - 3.7451 1 221125_WJC_METTL3_EV_vs_WT_F07.05813.05813.3 1.01E-05 15/48 K.TVEAEAAHGTVTR.H sp|O75874|IDHC_HUMAN 1 1340.6684 2.52 94707 5813 3 1340.666659 447.8968 Isocitrate dehydrogenase [NADP] cytoplasmic OS=Homo sapiens OX=9606 GN=IDH1 PE=1 SV=2 5.37 1541.9 - 2.91E+06 - - - -1.3299 - 2.826 0.541 - 238.9 1 2 0 -0.0018 13 0 0 0 6.32E+07 2.51E+07 - - - 7.3878 0.9974 221125_WJC_METTL3_EV_vs_WT_F07.05814.05814.2 0.00765 16-Oct K.NADGYKLDK.Q "sp|P55884|EIF3B_HUMAN,tr|C9JZG1|C9JZG1_HUMAN" 2 1022.5033 0.96 94708 5814 2 1022.503313 512.2589 Eukaryotic translation initiation factor 3 subunit B OS=Homo sapiens OX=9606 GN=EIF3B PE=1 SV=3 5.96 1542 - 1.93E+06 - - - 0.0372 - 1.92 0.398 - 340.6 1 2 1 0 9 0 0 0 2.36E+07 2.44E+07 - - - 3.8678 0.9853 221125_WJC_METTL3_EV_vs_WT_F07.05815.05815.2 0.0679 16-Nov K.NADGYK[136.11]LDK[136.11].Q "sp|P55884|EIF3B_HUMAN,tr|C9JZG1|C9JZG1_HUMAN" 2 1038.5317 0.96 94709 5815 2 1038.530992 520.2731 Eukaryotic translation initiation factor 3 subunit B OS=Homo sapiens OX=9606 GN=EIF3B PE=1 SV=3 5.96 1542.1 - 1.58E+06 - - - -0.6577 - 1.577 0.246 - 415.9 1 2 1 -0.0007 9 0 0 0 2.61E+07 2.73E+07 - - - 2.1756 0.9999 221125_WJC_METTL3_EV_vs_WT_F07.05817.05817.2 0.000165 22-Dec K.LVDQSGPPHEPK[136.11].F "sp|P55265|DSRAD_HUMAN,tr|A0A3B3IRQ9|A0A3B3IRQ9_HUMAN,tr|A0A3B3ISU1|A0A3B3ISU1_HUMAN,tr|A0A7P0Z4K3|A0A7P0Z4K3_HUMAN,tr|A0A3B3ISX1|A0A3B3ISX1_HUMAN,tr|A0A7P0Z4F9|A0A7P0Z4F9_HUMAN" 6 1310.671 0.26 94711 5817 2 1310.669795 656.3428 Double-stranded RNA-specific adenosine deaminase OS=Homo sapiens OX=9606 GN=ADAR PE=1 SV=4 5.32 1542.3 - 1.14E+06 - - - -0.9308 - 2.172 0.507 - 362.1 1 2 0 -0.0012 12 0 0 0 2.14E+06 8.34E+06 - - - 4.8262 1 221125_WJC_METTL3_EV_vs_WT_F07.05818.05818.2 1.47E-06 18/26 K.EEASGSSVTAEEAK.K sp|P13010|XRCC5_HUMAN 1 1393.6209 1.64 94712 5818 2 1393.621856 697.8177 X-ray repair cross-complementing protein 5 OS=Homo sapiens OX=9606 GN=XRCC5 PE=1 SV=3 4.09 1542.5 - 1.09E+06 - - - 0.6982 - 3.041 0.654 - 1355 1 2 0 0.001 14 0 0 0 4.38E+07 2.68E+07 - - - 6.6621 1 221125_WJC_METTL3_EV_vs_WT_F07.05819.05819.2 1.08E-08 15/26 K.EEASGSSVTAEEAK[136.11].K sp|P13010|XRCC5_HUMAN 1 1401.6351 1.64 94713 5819 2 1401.633773 701.8248 X-ray repair cross-complementing protein 5 OS=Homo sapiens OX=9606 GN=XRCC5 PE=1 SV=3 4.09 1542.6 - 851487 - - - -0.9346 - 3.146 0.661 - 964.8 1 2 0 -0.0013 14 0 0 0 4.38E+07 2.68E+07 - - - 6.7989 0.9996 221125_WJC_METTL3_EV_vs_WT_F07.05822.05822.3 0.000783 Nov-40 R.ALSQGVESVKK.E "sp|O43615|TIM44_HUMAN,tr|M0QXU7|M0QXU7_HUMAN" 2 1144.6452 1.01 94714 5822 3 1144.64364 382.5557 Mitochondrial import inner membrane translocase subunit TIM44 OS=Homo sapiens OX=9606 GN=TIMM44 PE=1 SV=2 8.64 1543 - 3.72E+07 - - - -1.3524 - 1.935 0.343 - 135.2 1 2 0 -0.0015 11 0 0 0 2.45E+08 2.44E+08 - - - 4.2389 0.9981 221125_WJC_METTL3_EV_vs_WT_F07.05824.05824.2 7.52E-05 18-Dec K.VQVEYKGETK.T "sp|P54652|HSP72_HUMAN,sp|P11142|HSP7C_HUMAN,tr|E9PQQ4|E9PQQ4_HUMAN,tr|E9PKE3|E9PKE3_HUMAN,tr|E9PN89|E9PN89_HUMAN,tr|E9PLF4|E9PLF4_HUMAN,tr|E9PK54|E9PK54_HUMAN,tr|E9PN25|E9PN25_HUMAN,tr|E9PPY6|E9PPY6_HUMAN,tr|E9PQK7|E9PQK7_HUMAN" 10 1179.6136 0.17 94716 5824 2 1179.615404 590.8141 Heat shock-related 70 kDa protein 2 OS=Homo sapiens OX=9606 GN=HSPA2 PE=1 SV=1 6.11 1543.1 - 9.87E+06 - - - 1.5692 - 2.276 0.539 - 610.7 1 2 1 0.0019 10 0 0 0 1.13E+08 6.53E+08 - - - 5.3171 0.9997 221125_WJC_METTL3_EV_vs_WT_F07.05825.05825.2 0.000224 20-Oct R.ALSQGVESVK[136.11]K[136.11].E "sp|O43615|TIM44_HUMAN,tr|M0QXU7|M0QXU7_HUMAN" 2 1160.6736 0.97 94717 5825 2 1160.672676 581.3441 Mitochondrial import inner membrane translocase subunit TIM44 OS=Homo sapiens OX=9606 GN=TIMM44 PE=1 SV=2 8.64 1543.1 - 8.88E+06 - - - -0.7858 - 1.835 0.434 - 263.4 1 2 0 -0.0009 11 0 0 0 5.13E+07 5.31E+07 - - - 3.8884 0.9998 221125_WJC_METTL3_EV_vs_WT_F07.05826.05826.2 6.63E-05 20-Oct R.ALSQGVESVKK.E "sp|O43615|TIM44_HUMAN,tr|M0QXU7|M0QXU7_HUMAN" 2 1144.6452 0.97 94718 5826 2 1144.64421 573.3299 Mitochondrial import inner membrane translocase subunit TIM44 OS=Homo sapiens OX=9606 GN=TIMM44 PE=1 SV=2 8.64 1543.1 - 7.14E+06 - - - -0.8544 - 1.981 0.442 - 316 1 2 0 -0.001 11 0 0 0 5.13E+07 5.31E+07 - - - 4.1546 0.9998 221125_WJC_METTL3_EV_vs_WT_F07.05827.05827.2 0.0217 16-Nov K.K[136.11]FVETPGQK[136.11].Y "sp|P05455|LA_HUMAN,tr|E7ERC4|E7ERC4_HUMAN" 2 1048.5888 0.99 94719 5827 2 1048.590042 525.3017 Lupus La protein OS=Homo sapiens OX=9606 GN=SSB PE=1 SV=2 8.59 1543.3 - 1.69E+06 - - - 1.1892 - 2.281 0.411 - 373.2 1 2 0 0.0012 9 0 0 0 2.15E+07 2.18E+07 - - - 4.4619 0.9995 221125_WJC_METTL3_EV_vs_WT_F07.05828.05828.2 9.24E-06 14-Sep R.YDDYSSSR.D "sp|Q96E39|RMXL1_HUMAN,sp|P38159|RBMX_HUMAN,tr|H3BUY5|H3BUY5_HUMAN" 3 991.3883 1.21 94720 5828 2 991.385543 496.7014 "RNA binding motif protein, X-linked-like-1 OS=Homo sapiens OX=9606 GN=RBMXL1 PE=1 SV=1" 4.21 1543.4 - 1.61E+06 - - - -2.785 - 1.808 0.541 - 252.6 1 2 0 -0.0028 8 0 0 0 8.13E+06 6.71E+06 - - - 4.8221 1 221125_WJC_METTL3_EV_vs_WT_F07.05830.05830.2 5.46E-09 14/22 R.QAGEVTYADAHK[136.11].G "sp|Q08170|SRSF4_HUMAN,sp|Q13247|SRSF6_HUMAN,tr|A0A590UK80|A0A590UK80_HUMAN,tr|A0A590UJK4|A0A590UJK4_HUMAN,tr|A0A590UJP7|A0A590UJP7_HUMAN,tr|A0A0D9SEM4|A0A0D9SEM4_HUMAN,tr|A0A590UK01|A0A590UK01_HUMAN" 7 1296.619 1.21 94722 5830 2 1296.619315 649.3168 Serine\arginine-rich splicing factor 4 OS=Homo sapiens OX=9606 GN=SRSF4 PE=1 SV=2 5.32 1543.7 - 1.52E+06 - - - 0.2584 - 2.445 0.606 - 742 1 2 0 0.0003 12 0 0 0 1.67E+07 1.38E+07 - - - 5.8692 1 221125_WJC_METTL3_EV_vs_WT_F07.05831.05831.2 7.87E-07 18/24 K.TVEAEAAHGTVTR.H sp|O75874|IDHC_HUMAN 1 1340.6684 2.25 94723 5831 2 1340.668596 671.3415 Isocitrate dehydrogenase [NADP] cytoplasmic OS=Homo sapiens OX=9606 GN=IDH1 PE=1 SV=2 5.37 1543.8 - 1.42E+06 - - - 0.1149 - 3.171 0.552 - 894.9 1 2 0 0.0002 13 0 0 0 1.01E+07 4.48E+06 - - - 6.0799 0.9988 221125_WJC_METTL3_EV_vs_WT_F07.05832.05832.3 0.0505 16/40 R.SPVKEPVEQPR.V sp|Q96T58|MINT_HUMAN 1 1264.6776 0.56 94724 5832 3 1264.6777 422.5665 Msx2-interacting protein OS=Homo sapiens OX=9606 GN=SPEN PE=1 SV=1 5.86 1543.9 - 1.04E+06 - - - 0.1178 - 2.745 0.261 - 434 1 2 1 0.0001 11 0 0 0 8.94E+06 1.59E+07 - - - 4.3185 0.9999 221125_WJC_METTL3_EV_vs_WT_F07.05837.05837.3 2.96E-05 Nov-36 K.LGIHEDSTNR[166.11].R sp|P08238|HS90B_HUMAN 1 1150.5606 0.84 94727 5837 3 1150.559262 384.5275 Heat shock protein HSP 90-beta OS=Homo sapiens OX=9606 GN=HSP90AB1 PE=1 SV=4 5.32 1544.5 - 7.57E+07 - - - -1.1803 - 1.844 0.466 - 176.2 1 2 0 -0.0014 10 0 0 0 4.93E+08 5.90E+08 - - - 5.5222 1 221125_WJC_METTL3_EV_vs_WT_F07.05839.05839.3 6.78E-07 Oct-36 K.LGIHEDSTNR.R sp|P08238|HS90B_HUMAN 1 1140.5523 0.83 94729 5839 3 1140.550878 381.1914 Heat shock protein HSP 90-beta OS=Homo sapiens OX=9606 GN=HSP90AB1 PE=1 SV=4 5.32 1544.5 - 5.49E+07 - - - -1.2906 - 2.093 0.528 - 147.5 1 2 0 -0.0015 10 0 0 0 4.91E+08 5.89E+08 - - - 6.5833 0.9965 221125_WJC_METTL3_EV_vs_WT_F07.05840.05840.2 1.01 12-Aug K.K[136.11]QLDSLR[166.11].E "sp|Q86U44|MTA70_HUMAN,tr|B4E349|B4E349_HUMAN,tr|F5H6D8|F5H6D8_HUMAN,tr|B4DTN4|B4DTN4_HUMAN" 4 876.5148 0.02 94730 5840 2 876.513304 439.2647 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 8.75 1544.6 - 3.19E+07 - - - -1.6908 - 1.699 0.145 - 289.9 1 2 0 -0.0015 7 0 0 0 5.21E+06 2.20E+08 - - - 1.791 0.9996 221125_WJC_METTL3_EV_vs_WT_F07.05842.05842.2 0.0036 18-Dec K.LGIHEDSTNR.R sp|P08238|HS90B_HUMAN 1 1140.5523 0.89 94732 5842 2 1140.550526 571.2835 Heat shock protein HSP 90-beta OS=Homo sapiens OX=9606 GN=HSP90AB1 PE=1 SV=4 5.32 1544.7 - 1.31E+07 - - - -1.5992 - 1.74 0.443 - 404 1 2 0 -0.0018 10 0 0 0 1.14E+08 1.28E+08 - - - 3.8585 0.9999 221125_WJC_METTL3_EV_vs_WT_F07.05843.05843.3 0.000145 13/36 K.VPGLQNEQKR.F "sp|Q8WWM7|ATX2L_HUMAN,tr|H3BUF6|H3BUF6_HUMAN" 2 1167.636 1.17 94733 5843 3 1167.635032 390.2193 Ataxin-2-like protein OS=Homo sapiens OX=9606 GN=ATXN2L PE=1 SV=2 8.72 1544.7 - 7.26E+06 - - - -0.8462 - 2.331 0.378 - 354.5 1 2 0 -0.001 10 0 0 0 4.46E+07 3.82E+07 - - - 5.2256 0.9998 221125_WJC_METTL3_EV_vs_WT_F07.05844.05844.2 0.000483 16-Oct R.QQHQGILSR.V sp|P49790|NU153_HUMAN 1 1065.5679 0.75 94734 5844 2 1065.567914 533.7912 Nuclear pore complex protein Nup153 OS=Homo sapiens OX=9606 GN=NUP153 PE=1 SV=2 9.76 1544.7 - 5.74E+06 - - - -0.0244 - 1.724 0.434 - 550.2 1 2 0 0 9 0 0 0 4.47E+07 5.96E+07 - - - 3.8222 1 221125_WJC_METTL3_EV_vs_WT_F07.05845.05845.3 1.55E-05 18/48 K.TVEAEAAHGTVTR[166.11].H sp|O75874|IDHC_HUMAN 1 1350.6767 2.52 94735 5845 3 1350.674996 451.2328 Isocitrate dehydrogenase [NADP] cytoplasmic OS=Homo sapiens OX=9606 GN=IDH1 PE=1 SV=2 5.37 1544.8 - 3.98E+06 - - - -1.2705 - 3.126 0.512 - 390.8 1 2 0 -0.0017 13 0 0 0 6.32E+07 2.51E+07 - - - 7.338 0.9997 221125_WJC_METTL3_EV_vs_WT_F07.05856.05856.2 0.00135 16-Sep R.SGSGWSSSR.G "sp|Q86YZ3|HORN_HUMAN,sp|Q86YZ3|HORN_HUMAN,sp|Q86YZ3|HORN_HUMAN,sp|Q86YZ3|HORN_HUMAN" 4 909.3941 105.08 94744 5856 2 909.392682 455.7043 Hornerin OS=Homo sapiens OX=9606 GN=HRNR PE=1 SV=2 9.47 1545.9 - 3.66E+07 - - - -1.5131 - 1.937 0.459 - 375.2 1 2 0 -0.0014 9 0 0 0 3.41E+08 3.24E+06 - - - 4.3435 0.9929 221125_WJC_METTL3_EV_vs_WT_F07.05859.05859.2 0.00924 18-Nov Y.GSGSGWSSSR.G "sp|Q86YZ3|HORN_HUMAN,sp|Q86YZ3|HORN_HUMAN,sp|Q86YZ3|HORN_HUMAN" 3 966.4155 282.95 94747 5859 2 966.414526 484.215 Hornerin OS=Homo sapiens OX=9606 GN=HRNR PE=1 SV=2 9.75 1546 - 1.33E+07 - - - -1.0306 - 2.343 0.523 - 563.3 1 1 0 -0.001 10 0 0 0 1.27E+08 4.49E+05 - - - 5.2802 0.9999 221125_WJC_METTL3_EV_vs_WT_F07.05860.05860.2 0.0012 18-Dec R.QEMQEVQSSR.S "sp|P22626|ROA2_HUMAN,tr|A0A024RA28|A0A024RA28_HUMAN,tr|A0A7I2V4N1|A0A7I2V4N1_HUMAN,tr|A0A7I2V4I6|A0A7I2V4I6_HUMAN,tr|A0A7I2V4S4|A0A7I2V4S4_HUMAN,tr|A0A7I2V323|A0A7I2V323_HUMAN,tr|A0A7I2V3P1|A0A7I2V3P1_HUMAN,tr|A0A7I2V3P7|A0A7I2V3P7_HUMAN" 8 1220.5456 1.29 94748 5860 2 1220.544753 611.2801 Heterogeneous nuclear ribonucleoproteins A2\B1 OS=Homo sapiens OX=9606 GN=HNRNPA2B1 PE=1 SV=2 4.53 1546.1 - 9.70E+06 - - - -0.653 - 2.521 0.497 - 923.3 1 2 0 -0.0008 10 0 0 0 7.37E+08 5.72E+08 - - - 5.2926 0.9999 221125_WJC_METTL3_EV_vs_WT_F07.05861.05861.2 0.000474 18-Nov R.QEMQEVQSSR[166.11].S "sp|P22626|ROA2_HUMAN,tr|A0A024RA28|A0A024RA28_HUMAN,tr|A0A7I2V4N1|A0A7I2V4N1_HUMAN,tr|A0A7I2V4I6|A0A7I2V4I6_HUMAN,tr|A0A7I2V4S4|A0A7I2V4S4_HUMAN,tr|A0A7I2V323|A0A7I2V323_HUMAN,tr|A0A7I2V3P1|A0A7I2V3P1_HUMAN,tr|A0A7I2V3P7|A0A7I2V3P7_HUMAN" 8 1230.5538 1.29 94749 5861 2 1230.553008 616.2842 Heterogeneous nuclear ribonucleoproteins A2\B1 OS=Homo sapiens OX=9606 GN=HNRNPA2B1 PE=1 SV=2 4.53 1546.1 - 8.57E+06 - - - -0.6599 - 2.439 0.456 - 687 1 2 0 -0.0008 10 0 0 0 7.37E+08 5.72E+08 - - - 4.8975 0.9651 221125_WJC_METTL3_EV_vs_WT_F07.05862.05862.2 1.92E-05 16-Oct L.GIHEDSTNR[166.11].R sp|P08238|HS90B_HUMAN 1 1037.4766 1.12 94750 5862 2 1037.476096 519.7456 Heat shock protein HSP 90-beta OS=Homo sapiens OX=9606 GN=HSP90AB1 PE=1 SV=4 5.32 1546.2 - 7.77E+06 - - - -0.4434 - 1.644 0.322 - 304.6 1 1 0 -0.0005 9 0 0 0 8.49E+07 7.58E+07 - - - 2.8574 1 221125_WJC_METTL3_EV_vs_WT_F07.05863.05863.2 0.000128 18/18 R.RTAQEVETYR.R "sp|P17844|DDX5_HUMAN,tr|J3QR02|J3QR02_HUMAN,tr|A0A7I2V507|A0A7I2V507_HUMAN,tr|J3KTA4|J3KTA4_HUMAN,tr|J3KTQ4|J3KTQ4_HUMAN,tr|A0A7I2V2S0|A0A7I2V2S0_HUMAN,tr|J3QRQ7|J3QRQ7_HUMAN" 7 1251.6208 1.71 94751 5863 2 1251.619456 626.8177 Probable ATP-dependent RNA helicase DDX5 OS=Homo sapiens OX=9606 GN=DDX5 PE=1 SV=1 6.14 1546.2 - 7.27E+06 - - - -1.045 - 2.895 0.548 - 602.3 1 2 0 -0.0013 10 0 0 0 6.63E+07 3.88E+07 - - - 6.0552 0.9999 221125_WJC_METTL3_EV_vs_WT_F07.05871.05871.2 8.27E-07 20-Nov R.ASYDTSAPNAK.R "sp|Q9HCE5|MET14_HUMAN,tr|A0A0D9SFW0|A0A0D9SFW0_HUMAN,tr|A0A0D9SF88|A0A0D9SF88_HUMAN,tr|D6RD73|D6RD73_HUMAN" 4 1123.5146 0.02 94759 5871 2 1123.514577 562.7646 N6-adenosine-methyltransferase non-catalytic subunit OS=Homo sapiens OX=9606 GN=METTL14 PE=1 SV=2 5.88 1546.9 - 1.66E+06 - - - 0.008 - 1.869 0.585 - 299 1 2 0 0 11 0 0 0 1.28E+07 5.42E+08 - - - 5.0537 1 221125_WJC_METTL3_EV_vs_WT_F07.05874.05874.2 3.80E-07 16/28 K.GGSISGGGYGSGGGK.H sp|P35908|K22E_HUMAN 1 1196.5422 636.6 94760 5874 2 1196.541207 599.2784 "Keratin, type II cytoskeletal 2 epidermal OS=Homo sapiens OX=9606 GN=KRT2 PE=1 SV=2" 8.59 1547.3 - 3.86E+07 - - - -0.8123 - 2.717 0.647 - 732.8 1 2 0 -0.001 15 0 0 0 1.07E+09 1.68E+06 - - - 6.2768 0.9932 221125_WJC_METTL3_EV_vs_WT_F07.05879.05879.2 0.666 12-Jul R.HNLSLNR[166.11].Y "sp|P85037|FOXK1_HUMAN,sp|Q01167|FOXK2_HUMAN,tr|E9PM37|E9PM37_HUMAN,tr|E9PPI7|E9PPI7_HUMAN" 4 862.4649 1.17 94765 5879 2 862.46409 432.2397 Forkhead box protein K1 OS=Homo sapiens OX=9606 GN=FOXK1 PE=1 SV=1 9.76 1547.5 - 3.77E+06 - - - -0.9032 - 1.409 0.116 - 137.8 1 2 0 -0.0008 7 0 0 0 3.37E+07 2.89E+07 - - - 0.984 0.9998 221125_WJC_METTL3_EV_vs_WT_F07.05880.05880.3 0.00125 Dec-48 R.LQSHPSTDGGLAR.G "sp|P10070|GLI2_HUMAN,tr|A0A7I2PJA1|A0A7I2PJA1_HUMAN" 2 1337.6688 1.6 94766 5880 3 1337.667394 446.8969 Zinc finger protein GLI2 OS=Homo sapiens OX=9606 GN=GLI2 PE=1 SV=4 6.74 1547.6 - 3.24E+06 - - - -1.0339 - 2.168 0.367 - 206.6 1 2 0 -0.0014 13 0 0 0 7.50E+07 4.70E+07 - - - 4.7293 0.9125 221125_WJC_METTL3_EV_vs_WT_F07.05881.05881.2 0.117 14-Aug L.SIC[160.03]SSDKR.L sp|Q13547|HDAC1_HUMAN 1 951.4444 1.03 94767 5881 2 951.443747 476.7295 Histone deacetylase 1 OS=Homo sapiens OX=9606 GN=HDAC1 PE=1 SV=1 7.94 1547.6 - 3.05E+06 - - - -0.6653 - 1.194 0.332 - 222.6 1 1 0 -0.0006 8 0 0 0 3.44E+07 3.35E+07 - - - 2.0277 0.9997 221125_WJC_METTL3_EV_vs_WT_F07.05882.05882.3 0.0235 13/40 R.ITTGAQDDLRK.V sp|Q9Y4W6|AFG32_HUMAN 1 1216.6412 1.47 94768 5882 3 1216.640423 406.5543 AFG3-like protein 2 OS=Homo sapiens OX=9606 GN=AFG3L2 PE=1 SV=2 5.96 1547.7 - 1.88E+06 - - - -0.6099 - 2.192 0.309 - 175.5 1 2 0 -0.0007 11 0 0 0 2.13E+07 1.45E+07 - - - 4.2144 0.9997 221125_WJC_METTL3_EV_vs_WT_F07.05884.05884.3 0.00445 13/48 R.LQSHPSTDGGLAR[166.11].G "sp|P10070|GLI2_HUMAN,tr|A0A7I2PJA1|A0A7I2PJA1_HUMAN" 2 1347.677 1.55 94770 5884 3 1347.677363 450.233 Zinc finger protein GLI2 OS=Homo sapiens OX=9606 GN=GLI2 PE=1 SV=4 6.74 1547.9 - 1.64E+06 - - - 0.2345 - 1.954 0.348 - 266.7 1 2 0 0.0003 13 0 0 0 7.52E+07 4.86E+07 - - - 4.236 0.9997 221125_WJC_METTL3_EV_vs_WT_F07.05892.05892.2 0.00133 18-Oct R.NIIHGSDSVK[136.11].S "sp|O60361|NDK8_HUMAN,sp|P22392|NDKB_HUMAN,tr|Q32Q12|Q32Q12_HUMAN" 3 1076.5706 1.03 94776 5892 2 1076.570426 539.2926 Putative nucleoside diphosphate kinase OS=Homo sapiens OX=9606 GN=NME2P1 PE=5 SV=1 6.74 1548.8 - 9.59E+06 - - - -0.1365 - 1.933 0.367 - 299.2 1 2 0 -0.0001 10 0 0 0 9.65E+07 9.39E+07 - - - 3.5913 0.9972 221125_WJC_METTL3_EV_vs_WT_F07.05894.05894.2 0.00119 16-Jul R.ISIC[160.03]SSDKR.L sp|Q13547|HDAC1_HUMAN 1 1064.5284 2.26 94778 5894 2 1064.528222 533.2715 Histone deacetylase 1 OS=Homo sapiens OX=9606 GN=HDAC1 PE=1 SV=1 8.22 1548.9 - 1.28E+07 - - - -0.2085 - 1.574 0.158 - 179.3 1 2 0 -0.0002 9 0 0 0 1.32E+08 5.82E+07 - - - 1.5203 0.9998 221125_WJC_METTL3_EV_vs_WT_F07.05896.05896.2 0.000224 20-Oct K.ANPFGGASHAK.G "sp|P62266|RS23_HUMAN,tr|D6RDJ2|D6RDJ2_HUMAN,tr|D6R9I7|D6R9I7_HUMAN,tr|D6RD47|D6RD47_HUMAN,tr|D6RIX0|D6RIX0_HUMAN" 5 1055.5148 0.79 94780 5896 2 1055.513949 528.7647 40S ribosomal protein S23 OS=Homo sapiens OX=9606 GN=RPS23 PE=1 SV=3 8.8 1548.9 - 6.11E+06 - - - -0.846 - 1.77 0.457 - 342.2 1 2 0 -0.0009 11 0 0 0 1.18E+08 1.49E+08 - - - 3.9608 0.9976 221125_WJC_METTL3_EV_vs_WT_F07.05898.05898.2 0.00199 15/18 K.EIRPTYAGSK.S "sp|O75956|CDKA2_HUMAN,sp|O14519|CDKA1_HUMAN,tr|E9PKR4|E9PKR4_HUMAN,tr|F5GZF0|F5GZF0_HUMAN" 4 1120.5877 1.41 94782 5898 2 1120.585737 561.3011 Cyclin-dependent kinase 2-associated protein 2 OS=Homo sapiens OX=9606 GN=CDK2AP2 PE=1 SV=1 8.69 1549.1 - 1.32E+06 - - - -1.7277 - 2.295 0.104 - 791 1 2 0 -0.0019 10 0 0 0 3.87E+07 2.74E+07 - - - 2.1274 0.9992 221125_WJC_METTL3_EV_vs_WT_F07.05900.05900.2 6.21E-06 24-Dec R.NPQNSSQSADGLR[166.11].C sp|Q01081|U2AF1_HUMAN 1 1382.6414 0.73 94784 5900 2 1382.64344 692.328 Splicing factor U2AF 35 kDa subunit OS=Homo sapiens OX=9606 GN=U2AF1 PE=1 SV=3 5.84 1549.4 - 807990 - - - 1.4827 - 2.476 0.238 - 522.7 1 2 0 0.0021 13 0 0 0 8.04E+06 1.10E+07 - - - 3.1252 0.9821 221125_WJC_METTL3_EV_vs_WT_F07.05901.05901.2 0.00681 24-Oct R.NPQNSSQSADGLR.C sp|Q01081|U2AF1_HUMAN 1 1372.6331 0.73 94785 5901 2 1373.635917 687.3238 Splicing factor U2AF 35 kDa subunit OS=Homo sapiens OX=9606 GN=U2AF1 PE=1 SV=3 5.84 1549.5 - 555460 - - - 730.5645 - 2.032 0.354 - 178.1 1 2 0 1.0028 13 0 0 0 8.04E+06 1.10E+07 - - - 3.1605 0.997 221125_WJC_METTL3_EV_vs_WT_F07.05903.05903.2 0.000465 18-Nov R.YK[136.11]ADLATDQK[136.11].E sp|Q13895|BYST_HUMAN 1 1167.6107 0.65 94786 5903 2 1167.608945 584.8126 Bystin OS=Homo sapiens OX=9606 GN=BYSL PE=1 SV=3 5.96 1549.7 - 1.03E+06 - - - -1.4628 - 2.338 0.384 - 213.3 1 2 1 -0.0017 10 0 0 0 4.36E+06 6.75E+06 - - - 4.2473 0.913 221125_WJC_METTL3_EV_vs_WT_F07.05905.05905.2 0.0137 16-Jun N.PFGGASHAK.G "sp|P62266|RS23_HUMAN,tr|D6RDJ2|D6RDJ2_HUMAN,tr|D6R9I7|D6R9I7_HUMAN,tr|D6RD47|D6RD47_HUMAN,tr|D6RIX0|D6RIX0_HUMAN" 5 870.4348 1.09 94787 5905 2 870.434178 436.2247 40S ribosomal protein S23 OS=Homo sapiens OX=9606 GN=RPS23 PE=1 SV=3 9.18 1549.9 - 1.06E+07 - - - -0.7157 - 1.194 0.337 - 54.4 1 1 0 -0.0006 9 0 0 0 1.32E+08 1.21E+08 - - - 2.0429 0.9986 221125_WJC_METTL3_EV_vs_WT_F07.05909.05909.3 0.0296 Nov-32 R.TR[166.11]EEIQEVR[166.11].S "sp|P08559|ODPA_HUMAN,sp|P29803|ODPAT_HUMAN,tr|Q5JPU3|Q5JPU3_HUMAN" 3 1178.6158 0.25 94791 5909 3 1178.616779 393.8792 "Pyruvate dehydrogenase E1 component subunit alpha, somatic form, mitochondrial OS=Homo sapiens OX=9606 GN=PDHA1 PE=1 SV=3" 4.78 1550.1 - 6.08E+06 - - - 0.7967 - 2.05 0.318 - 247.5 1 2 1 0.0009 9 0 0 0 4.10E+07 1.67E+08 - - - 4.2485 0.9467 221125_WJC_METTL3_EV_vs_WT_F07.05910.05910.2 0.12 14-May S.SSQSLEHR.L "sp|Q5H9F3|BCORL_HUMAN,tr|H7C4B2|H7C4B2_HUMAN" 2 942.4519 55.59 94792 5910 2 942.451042 472.2332 BCL-6 corepressor-like protein 1 OS=Homo sapiens OX=9606 GN=BCORL1 PE=1 SV=1 6.47 1550.1 - 4.11E+06 - - - -0.9189 - 1.301 0.369 - 119.9 1 1 0 -0.0009 8 0 0 0 4.84E+07 8.71E+05 - - - 2.5598 0.9997 221125_WJC_METTL3_EV_vs_WT_F07.05913.05913.2 0.000673 20-Nov R.ESEALDSPNSK.G sp|P0C7T5|ATX1L_HUMAN 1 1175.5306 1.14 94795 5913 2 1175.52862 588.7726 Ataxin-1-like OS=Homo sapiens OX=9606 GN=ATXN1L PE=1 SV=1 4.14 1550.4 - 1.37E+06 - - - -1.6946 - 2.08 0.427 - 472.4 1 2 0 -0.002 11 0 0 0 1.16E+07 1.02E+07 - - - 4.1754 0.9341 221125_WJC_METTL3_EV_vs_WT_F07.05921.05921.2 0.00722 16-Aug N.PFGGASHAK[136.11].G "sp|P62266|RS23_HUMAN,tr|D6RDJ2|D6RDJ2_HUMAN,tr|D6R9I7|D6R9I7_HUMAN,tr|D6RD47|D6RD47_HUMAN,tr|D6RIX0|D6RIX0_HUMAN" 5 878.449 1.09 94801 5921 2 878.449075 440.2318 40S ribosomal protein S23 OS=Homo sapiens OX=9606 GN=RPS23 PE=1 SV=3 9.18 1551.5 - 1.10E+07 - - - 0.0842 - 1.346 0.316 - 116.9 1 1 0 0.0001 9 0 0 0 1.25E+08 1.14E+08 - - - 2.2346 1 221125_WJC_METTL3_EV_vs_WT_F07.05923.05923.2 8.82E-10 13/24 K.ANGTSALTAQNGK[136.11].A "sp|Q14978|NOLC1_HUMAN,tr|A0A0A0MRM9|A0A0A0MRM9_HUMAN" 2 1239.6299 1.82 94803 5923 2 1239.629707 620.8222 Nucleolar and coiled-body phosphoprotein 1 OS=Homo sapiens OX=9606 GN=NOLC1 PE=1 SV=2 8.8 1551.6 - 5.85E+06 - - - -0.1388 - 2.816 0.669 - 806.6 1 2 0 -0.0002 13 0 0 0 1.23E+08 6.73E+07 - - - 6.6394 0.9997 221125_WJC_METTL3_EV_vs_WT_F07.05925.05925.3 6.64E-05 14/48 R.TKTPGPGAQSALR.A "sp|P62263|RS14_HUMAN,tr|A0A2R8Y811|A0A2R8Y811_HUMAN,tr|E5RH77|E5RH77_HUMAN" 3 1282.6993 1.35 94805 5925 3 1282.698447 428.5737 40S ribosomal protein S14 OS=Homo sapiens OX=9606 GN=RPS14 PE=1 SV=3 11 1551.7 - 3.16E+06 - - - -0.7032 - 2.952 0.384 - 309.5 1 2 1 -0.0009 13 0 0 0 5.68E+07 4.21E+07 - - - 5.7559 0.9996 221125_WJC_METTL3_EV_vs_WT_F07.05926.05926.2 0.00128 18-Dec K.EIR[166.11]PTYAGSK[136.11].S "sp|O75956|CDKA2_HUMAN,sp|O14519|CDKA1_HUMAN,tr|E9PKR4|E9PKR4_HUMAN,tr|F5GZF0|F5GZF0_HUMAN" 4 1138.6101 1.84 94806 5926 2 1138.612004 570.3123 Cyclin-dependent kinase 2-associated protein 2 OS=Homo sapiens OX=9606 GN=CDK2AP2 PE=1 SV=1 8.69 1551.7 - 2.68E+06 - - - 1.6344 - 2.638 0.312 - 531.8 1 2 0 0.0019 10 0 0 0 3.56E+07 1.94E+07 - - - 4.0525 0.9997 221125_WJC_METTL3_EV_vs_WT_F07.05927.05927.2 0.00175 18-Sep R.DISTLNSGK[136.11]K[136.11].S "sp|P04843|RPN1_HUMAN,tr|B7Z4L4|B7Z4L4_HUMAN" 2 1077.6001 1.71 94807 5927 2 1077.599118 539.8073 Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit 1 OS=Homo sapiens OX=9606 GN=RPN1 PE=1 SV=1 8.59 1551.8 - 2.57E+06 - - - -0.9001 - 1.861 0.382 - 172.7 1 2 0 -0.001 10 0 0 0 3.07E+07 1.80E+07 - - - 3.5959 0.9999 221125_WJC_METTL3_EV_vs_WT_F07.05929.05929.2 0.000271 18-Nov K.ASQLSVQQNK.L "sp|A0A1B0GTU1|ZC11B_HUMAN,sp|O75152|ZC11A_HUMAN,tr|E9PBY7|E9PBY7_HUMAN,tr|A0A1W2PPR9|A0A1W2PPR9_HUMAN,tr|A0A494C0C4|A0A494C0C4_HUMAN,tr|E9PQ61|E9PQ61_HUMAN" 6 1101.5778 0.98 94809 5929 2 1101.577131 551.7962 Zinc finger CCCH domain-containing protein 11B OS=Homo sapiens OX=9606 GN=ZC3H11B PE=4 SV=1 8.8 1551.9 - 1.25E+06 - - - -0.64 - 2.172 0.464 - 388.3 1 2 0 -0.0007 10 0 0 0 2.47E+07 2.51E+07 - - - 4.633 1 221125_WJC_METTL3_EV_vs_WT_F07.05930.05930.3 2.85E-05 15/48 K.AAMDNSEIAGEKK.S "sp|Q16891|MIC60_HUMAN,tr|B9A067|B9A067_HUMAN,tr|C9J406|C9J406_HUMAN,tr|H7C463|H7C463_HUMAN" 4 1362.6449 1.34 94810 5930 3 1362.643755 455.2223 MICOS complex subunit MIC60 OS=Homo sapiens OX=9606 GN=IMMT PE=1 SV=1 4.68 1552 - 650264 - - - -0.8623 - 2.76 0.58 - 329.3 1 2 0 -0.0012 13 0 0 0 3.89E+07 2.90E+07 - - - 7.7587 0.9977 221125_WJC_METTL3_EV_vs_WT_F07.05935.05935.2 0.00917 16-Aug K.NSTWSGESK[136.11].T "sp|P19338|NUCL_HUMAN,tr|A0A7I2V506|A0A7I2V506_HUMAN,tr|A0A7I2V2U7|A0A7I2V2U7_HUMAN,tr|A0A7I2V3F3|A0A7I2V3F3_HUMAN,tr|A0A7I2V428|A0A7I2V428_HUMAN,tr|A0A7I2V349|A0A7I2V349_HUMAN,tr|A0A7I2V5M5|A0A7I2V5M5_HUMAN,tr|C9JLB1|C9JLB1_HUMAN" 8 1002.4498 0.94 94813 5935 2 1002.449869 502.2322 Nucleolin OS=Homo sapiens OX=9606 GN=NCL PE=1 SV=3 6 1552.7 - 2.18E+07 - - - 0.0798 - 1.694 0.151 - 372.9 1 2 0 0.0001 9 0 0 0 1.80E+08 1.91E+08 - - - 1.6812 0.9999 221125_WJC_METTL3_EV_vs_WT_F07.05936.05936.2 0.000388 18-Oct K.SQESNVSIQK.E "sp|Q15643|TRIPB_HUMAN,tr|H0YJ97|H0YJ97_HUMAN" 2 1118.5568 1.12 94814 5936 2 1118.557232 560.2857 Thyroid receptor-interacting protein 11 OS=Homo sapiens OX=9606 GN=TRIP11 PE=1 SV=3 5.72 1552.7 - 1.73E+07 - - - 0.4157 - 2.201 0.457 - 429 1 2 0 0.0005 10 0 0 0 1.02E+08 9.11E+07 - - - 4.6183 1 221125_WJC_METTL3_EV_vs_WT_F07.05937.05937.3 5.46E-06 13/40 R.MEELHNQEVQK[136.11].R "sp|Q15233|NONO_HUMAN,tr|A0A7I2V535|A0A7I2V535_HUMAN,tr|A0A7I2V4N2|A0A7I2V4N2_HUMAN,tr|A0A7I2V4K9|A0A7I2V4K9_HUMAN,tr|A0A7I2V464|A0A7I2V464_HUMAN,tr|A0A7P0MRW0|A0A7P0MRW0_HUMAN,tr|H7C367|H7C367_HUMAN,tr|A0A7I2V4J2|A0A7I2V4J2_HUMAN,tr|A0A7I2V5Y7|A0A7I2V5Y7_HUMAN,tr|C9JYS8|C9JYS8_HUMAN" 10 1391.6595 0.75 94815 5937 3 1391.659433 464.8938 Non-POU domain-containing octamer-binding protein OS=Homo sapiens OX=9606 GN=NONO PE=1 SV=4 4.75 1552.8 - 6.95E+06 - - - -0.0223 - 2.338 0.497 - 209.3 1 2 0 0 11 0 0 0 4.03E+07 5.40E+07 - - - 6.4938 0.9982 221125_WJC_METTL3_EV_vs_WT_F07.05938.05938.3 0.000798 Dec-36 K.AMVNK[136.11]DDIQK[136.11].M "sp|P35580|MYH10_HUMAN,tr|E7ERA5|E7ERA5_HUMAN" 2 1176.6144 1.32 94816 5938 3 1176.614127 393.2121 Myosin-10 OS=Homo sapiens OX=9606 GN=MYH10 PE=1 SV=3 6 1552.8 - 4.15E+06 - - - -0.1963 - 2.19 0.286 - 170.5 1 2 1 -0.0002 10 0 0 0 5.85E+07 4.43E+07 - - - 4.0179 0.9999 221125_WJC_METTL3_EV_vs_WT_F07.05939.05939.2 0.00192 16-Nov R.NAAEELKPR.N sp|P78406|RAE1L_HUMAN 1 1026.5458 2.4 94817 5939 2 1026.546176 514.2802 mRNA export factor OS=Homo sapiens OX=9606 GN=RAE1 PE=1 SV=1 6.14 1552.9 - 3.90E+06 - - - 0.3585 - 2.128 0.474 - 712.5 1 2 0 0.0004 9 0 0 0 2.88E+07 1.20E+07 - - - 4.7266 0.9996 221125_WJC_METTL3_EV_vs_WT_F07.05941.05941.2 0.00225 18-Oct K.ASQLSVQQNK[136.11].L "sp|A0A1B0GTU1|ZC11B_HUMAN,sp|O75152|ZC11A_HUMAN,tr|E9PBY7|E9PBY7_HUMAN,tr|A0A1W2PPR9|A0A1W2PPR9_HUMAN,tr|A0A494C0C4|A0A494C0C4_HUMAN,tr|E9PQ61|E9PQ61_HUMAN" 6 1109.592 1.01 94819 5941 2 1109.592434 555.8033 Zinc finger CCCH domain-containing protein 11B OS=Homo sapiens OX=9606 GN=ZC3H11B PE=4 SV=1 8.8 1553 - 3.45E+06 - - - 0.3587 - 1.882 0.338 - 323.3 1 2 0 0.0004 10 0 0 0 2.47E+07 2.44E+07 - - - 3.3024 0.9997 221125_WJC_METTL3_EV_vs_WT_F07.05942.05942.3 0.0211 Oct-40 K.MKDTDSEEEIR.E "sp|P0DP25|CALM3_HUMAN,sp|P0DP23|CALM1_HUMAN,sp|P0DP24|CALM2_HUMAN,tr|G3V361|G3V361_HUMAN,tr|A0A590UJI2|A0A590UJI2_HUMAN,tr|Q96HY3|Q96HY3_HUMAN,tr|A0A590UJC0|A0A590UJC0_HUMAN,tr|G3V226|G3V226_HUMAN,tr|E7EMB3|E7EMB3_HUMAN" 9 1351.5926 0.98 94820 5942 3 1351.592749 451.5381 Calmodulin-3 OS=Homo sapiens OX=9606 GN=CALM3 PE=1 SV=1 4.18 1553 - 2.91E+06 - - - 0.1398 - 1.994 0.461 - 229.3 1 2 1 0.0002 11 0 0 0 1.84E+07 1.88E+07 - - - 5.6402 0.9995 221125_WJC_METTL3_EV_vs_WT_F07.05943.05943.2 0.0484 16-Oct K.KQQQLSALK.V sp|P35580|MYH10_HUMAN 1 1042.6135 0.72 94821 5943 2 1042.614075 522.314 Myosin-10 OS=Homo sapiens OX=9606 GN=MYH10 PE=1 SV=3 10 1553.1 - 2.05E+06 - - - 0.5573 - 1.792 0.335 - 353.4 1 2 0 0.0006 9 0 0 0 9.91E+06 1.38E+07 - - - 3.2027 0.9989 221125_WJC_METTL3_EV_vs_WT_F07.05946.05946.2 0.00219 16-Sep R.SSPVESLK[136.11]K[136.11].E "sp|Q9NRA8|4ET_HUMAN,tr|B1AKL5|B1AKL5_HUMAN,tr|B1AKL4|B1AKL4_HUMAN" 3 989.5728 1.2 94824 5946 2 989.573838 495.7937 Eukaryotic translation initiation factor 4E transporter OS=Homo sapiens OX=9606 GN=EIF4ENIF1 PE=1 SV=2 8.31 1553.4 - 1.30E+06 - - - 1.0378 - 1.506 0.319 - 221.2 1 2 0 0.001 9 0 0 0 1.63E+07 1.36E+07 - - - 2.5814 0.9987 221125_WJC_METTL3_EV_vs_WT_F07.05948.05948.2 0.0185 18-Jul R.NIDPK[136.11]PC[160.03]TPR[166.11].G "sp|Q96EP5|DAZP1_HUMAN,tr|K7EK33|K7EK33_HUMAN,tr|K7EQ55|K7EQ55_HUMAN" 3 1214.6197 0.89 94826 5948 2 1214.620039 608.3171 DAZ-associated protein 1 OS=Homo sapiens OX=9606 GN=DAZAP1 PE=1 SV=1 8.22 1553.6 - 744509 - - - 0.3104 - 1.501 0.271 - 164.7 1 2 0 0.0004 10 0 0 0 8.07E+06 9.04E+06 - - - 2.1761 1 221125_WJC_METTL3_EV_vs_WT_F07.05949.05949.2 7.86E-06 20-Dec K.MKDTDSEEEIR.E "sp|P0DP25|CALM3_HUMAN,sp|P0DP23|CALM1_HUMAN,sp|P0DP24|CALM2_HUMAN,tr|G3V361|G3V361_HUMAN,tr|A0A590UJI2|A0A590UJI2_HUMAN,tr|Q96HY3|Q96HY3_HUMAN,tr|A0A590UJC0|A0A590UJC0_HUMAN,tr|G3V226|G3V226_HUMAN,tr|E7EMB3|E7EMB3_HUMAN" 9 1351.5926 1.92 94827 5949 2 1351.591109 676.8036 Calmodulin-3 OS=Homo sapiens OX=9606 GN=CALM3 PE=1 SV=1 4.18 1553.8 - 334346 - - - -1.0735 - 2.439 0.578 - 374 1 2 1 -0.0015 11 0 0 0 3.85E+06 2.01E+06 - - - 5.7216 0.9941 221125_WJC_METTL3_EV_vs_WT_F07.05950.05950.2 1.06E-07 22-Oct A.ASSYSASAEPAR[166.11].V sp|Q9BV79|MECR_HUMAN 1 1205.5552 150.76 94828 5950 2 1205.554654 603.7849 "Enoyl-[acyl-carrier-protein] reductase, mitochondrial OS=Homo sapiens OX=9606 GN=MECR PE=1 SV=2" 6.05 1553.9 - 201545 - - - -0.4529 - 2.034 0.593 - 377.8 1 1 0 -0.0005 12 0 0 0 3.37E+08 2.24E+06 - - - 5.2889 0.884 221125_WJC_METTL3_EV_vs_WT_F07.05953.05953.3 0.35 Oct-36 K.AMVNKDDIQK.M "sp|P35580|MYH10_HUMAN,tr|E7ERA5|E7ERA5_HUMAN" 2 1160.586 0.98 94829 5953 3 1160.586156 387.8693 Myosin-10 OS=Homo sapiens OX=9606 GN=MYH10 PE=1 SV=3 6 1554.3 - 6.37E+06 - - - 0.1706 - 1.896 0.071 - 106.2 1 2 1 0.0002 10 0 0 0 6.06E+07 6.16E+07 - - - 1.1999 1 221125_WJC_METTL3_EV_vs_WT_F07.05956.05956.2 2.63E-07 20-Nov R.FC[160.03]ENTQAGEGR.V "sp|Q92896|GSLG1_HUMAN,tr|H3BM42|H3BM42_HUMAN" 2 1267.5251 1.29 94832 5956 2 1267.525143 634.7699 Golgi apparatus protein 1 OS=Homo sapiens OX=9606 GN=GLG1 PE=1 SV=2 4.53 1554.6 - 1.27E+06 - - - -0.0047 - 2.261 0.613 - 402.9 1 2 0 0 11 0 0 0 7.25E+06 5.63E+06 - - - 5.7756 1 221125_WJC_METTL3_EV_vs_WT_F07.05957.05957.3 4.04E-05 Dec-52 K.VAAQC[160.03]SHAAVSAYK[136.11].Q "sp|Q9Y3E5|PTH2_HUMAN,tr|J3KQ48|J3KQ48_HUMAN" 2 1469.7176 1.6 94833 5957 3 1469.717204 490.9132 "Peptidyl-tRNA hydrolase 2, mitochondrial OS=Homo sapiens OX=9606 GN=PTRH2 PE=1 SV=1" 8.18 1554.7 - 1.16E+06 - - - -0.3021 - 2.341 0.506 - 152.6 1 2 0 -0.0004 14 0 0 0 1.08E+07 6.77E+06 - - - 6.4417 0.9988 221125_WJC_METTL3_EV_vs_WT_F07.05958.05958.2 6.14E-05 18-Nov K.AMVNKDDIQK.M "sp|P35580|MYH10_HUMAN,tr|E7ERA5|E7ERA5_HUMAN" 2 1160.586 2.02 94834 5958 2 1160.586362 581.3003 Myosin-10 OS=Homo sapiens OX=9606 GN=MYH10 PE=1 SV=3 6 1554.8 - 977273 - - - 0.3481 - 2.449 0.488 - 471.8 1 2 1 0.0004 10 0 0 0 3.36E+07 1.66E+07 - - - 5.1454 1 221125_WJC_METTL3_EV_vs_WT_F07.05959.05959.2 4.14E-06 20-Dec R.FC[160.03]ENTQAGEGR[166.11].V "sp|Q92896|GSLG1_HUMAN,tr|H3BM42|H3BM42_HUMAN" 2 1277.5334 1.29 94835 5959 2 1277.533758 639.774 Golgi apparatus protein 1 OS=Homo sapiens OX=9606 GN=GLG1 PE=1 SV=2 4.53 1554.9 - 956983 - - - 0.2654 - 2.329 0.598 - 483.9 1 2 0 0.0003 11 0 0 0 7.25E+06 5.63E+06 - - - 5.7448 1 221125_WJC_METTL3_EV_vs_WT_F07.05960.05960.2 1.77E-06 14/20 R.MEELHNQEVQK[136.11].R "sp|Q15233|NONO_HUMAN,tr|A0A7I2V535|A0A7I2V535_HUMAN,tr|A0A7I2V4N2|A0A7I2V4N2_HUMAN,tr|A0A7I2V4K9|A0A7I2V4K9_HUMAN,tr|A0A7I2V464|A0A7I2V464_HUMAN,tr|A0A7P0MRW0|A0A7P0MRW0_HUMAN,tr|H7C367|H7C367_HUMAN,tr|A0A7I2V4J2|A0A7I2V4J2_HUMAN,tr|A0A7I2V5Y7|A0A7I2V5Y7_HUMAN,tr|C9JYS8|C9JYS8_HUMAN" 10 1391.6595 1.81 94836 5960 2 1391.659295 696.837 Non-POU domain-containing octamer-binding protein OS=Homo sapiens OX=9606 GN=NONO PE=1 SV=4 4.75 1555 - 781007 - - - -0.1214 - 2.771 0.625 - 897.4 1 2 0 -0.0002 11 0 0 0 7.90E+06 4.35E+06 - - - 6.4144 0.998 221125_WJC_METTL3_EV_vs_WT_F07.05961.05961.2 0.0256 22-Sep K.SYSVGASGSSSR[166.11].K "sp|Q8N684|CPSF7_HUMAN,tr|F5H669|F5H669_HUMAN" 2 1153.5239 0.33 94837 5961 2 1153.527767 577.7692 Cleavage and polyadenylation specificity factor subunit 7 OS=Homo sapiens OX=9606 GN=CPSF7 PE=1 SV=1 8.46 1555.1 - 735700 - - - 3.3523 - 1.735 0.402 - 270.6 1 2 0 0.0039 12 0 0 0 7.09E+06 2.15E+07 - - - 3.4588 1 221125_WJC_METTL3_EV_vs_WT_F07.05963.05963.2 9.19E-10 14/24 K.AAMDNSEIAGEKK.S "sp|Q16891|MIC60_HUMAN,tr|B9A067|B9A067_HUMAN,tr|C9J406|C9J406_HUMAN,tr|H7C463|H7C463_HUMAN" 4 1362.6449 2.31 94839 5963 2 1362.643814 682.3297 MICOS complex subunit MIC60 OS=Homo sapiens OX=9606 GN=IMMT PE=1 SV=1 4.68 1555.4 - 637101 - - - -0.819 - 2.853 0.659 - 619.6 1 2 0 -0.0011 13 0 0 0 3.70E+06 1.60E+06 - - - 6.5987 0.9998 221125_WJC_METTL3_EV_vs_WT_F07.05971.05971.3 5.31E-06 15/48 R.TK[136.11]TPGPGAQSALR[166.11].A "sp|P62263|RS14_HUMAN,tr|A0A2R8Y811|A0A2R8Y811_HUMAN,tr|E5RH77|E5RH77_HUMAN" 3 1300.7218 1.49 94845 5971 3 1300.722689 434.5812 40S ribosomal protein S14 OS=Homo sapiens OX=9606 GN=RPS14 PE=1 SV=3 11 1556.3 - 3.83E+06 - - - 0.6689 - 3.033 0.402 - 426.8 1 2 1 0.0009 13 0 0 0 6.40E+07 4.29E+07 - - - 6.03 0.994 221125_WJC_METTL3_EV_vs_WT_F07.05972.05972.2 0.569 16-Sep K.R[166.11]ETGVDLTK[136.11].D "sp|P38646|GRP75_HUMAN,tr|H0Y8K0|H0Y8K0_HUMAN,tr|A0A7I2V2G2|A0A7I2V2G2_HUMAN,tr|A0A7I2V3F7|A0A7I2V3F7_HUMAN,tr|A0A7I2YQB2|A0A7I2YQB2_HUMAN,tr|D6RCD7|D6RCD7_HUMAN" 6 1035.5679 0.36 94846 5972 2 1035.568552 518.7912 "Stress-70 protein, mitochondrial OS=Homo sapiens OX=9606 GN=HSPA9 PE=1 SV=2" 6.07 1556.4 - 3.12E+06 - - - 0.5871 - 1.74 0.056 - 335.9 1 2 0 0.0006 9 0 0 0 1.64E+07 4.55E+07 - - - 1.0568 0.9972 221125_WJC_METTL3_EV_vs_WT_F07.05977.05977.2 0.0497 16-Sep R.ENIQQVSQK.E "sp|Q8N573|OXR1_HUMAN,tr|H0YC07|H0YC07_HUMAN" 2 1072.5513 1.21 94851 5977 2 1072.553957 537.2829 Oxidation resistance protein 1 OS=Homo sapiens OX=9606 GN=OXR1 PE=1 SV=2 6.1 1556.6 - 2.03E+06 - - - 2.4894 - 1.679 0.266 - 337.4 1 2 0 0.0027 9 0 0 0 2.10E+07 1.74E+07 - - - 2.504 0.9979 221125_WJC_METTL3_EV_vs_WT_F07.05978.05978.2 0.0769 18-Aug R.NIDPKPC[160.03]TPR.G "sp|Q96EP5|DAZP1_HUMAN,tr|K7EK33|K7EK33_HUMAN,tr|K7EQ55|K7EQ55_HUMAN" 3 1196.5972 0.98 94852 5978 2 1196.599106 599.3059 DAZ-associated protein 1 OS=Homo sapiens OX=9606 GN=DAZAP1 PE=1 SV=1 8.22 1556.7 - 885651 - - - 1.5995 - 1.453 0.292 - 225.3 1 2 0 0.0019 10 0 0 0 8.26E+06 8.43E+06 - - - 2.24 0.8429 221125_WJC_METTL3_EV_vs_WT_F07.05979.05979.2 0.121 20-Jul K.ETSKDTETVLK.T sp|Q9NP61|ARFG3_HUMAN 1 1249.6402 1.25 94853 5979 2 1249.643605 625.8274 ADP-ribosylation factor GTPase-activating protein 3 OS=Homo sapiens OX=9606 GN=ARFGAP3 PE=1 SV=1 4.68 1556.8 - 747734 - - - 2.7552 - 1.374 0.178 - 116.3 1 2 1 0.0034 11 0 0 0 6.38E+06 5.11E+06 - - - 1.2142 0.9999 221125_WJC_METTL3_EV_vs_WT_F07.05982.05982.2 1.31E-05 26-Dec K.ASIQAASAESSGQK.S "sp|Q5QJE6|TDIF2_HUMAN,tr|E9PRB3|E9PRB3_HUMAN,tr|J3KP30|J3KP30_HUMAN" 3 1333.6474 1.33 94856 5982 2 1333.64676 667.831 Deoxynucleotidyltransferase terminal-interacting protein 2 OS=Homo sapiens OX=9606 GN=DNTTIP2 PE=1 SV=2 6.05 1557.2 - 465830 - - - -0.4596 - 2.251 0.554 - 385.3 1 2 0 -0.0006 14 0 0 0 3.04E+06 2.29E+06 - - - 5.1688 0.9842 221125_WJC_METTL3_EV_vs_WT_F07.05991.05991.2 0.0117 18-Oct L.SSVQENIQQK.S "sp|P52732|KIF11_HUMAN,tr|A0A7I2V3A9|A0A7I2V3A9_HUMAN" 2 1159.5833 3.24 94863 5991 2 1159.583964 580.7989 Kinesin-like protein KIF11 OS=Homo sapiens OX=9606 GN=KIF11 PE=1 SV=2 5.72 1558.2 - 4.98E+06 - - - 0.5588 - 2.037 0.381 - 575.2 1 1 0 0.0006 10 0 0 0 3.85E+07 1.19E+07 - - - 3.8408 0.9999 221125_WJC_METTL3_EV_vs_WT_F07.05992.05992.3 0.000319 Sep-40 R.IVNTQEQLNHR.W sp|O15020|SPTN2_HUMAN 1 1350.7004 1.74 94864 5992 3 1350.702328 451.2407 "Spectrin beta chain, non-erythrocytic 2 OS=Homo sapiens OX=9606 GN=SPTBN2 PE=1 SV=3" 6.75 1558.3 - 3.57E+06 - - - 1.4193 - 1.996 0.446 - 144.3 1 2 0 0.0019 11 0 0 0 1.68E+07 9.62E+06 - - - 5.4754 0.9015 221125_WJC_METTL3_EV_vs_WT_F07.05993.05993.2 0.834 14-Aug K.EKIEELNK.T "sp|O75179|ANR17_HUMAN,tr|H0YM23|H0YM23_HUMAN,tr|A0A1W2PQ15|A0A1W2PQ15_HUMAN,tr|H0YLQ3|H0YLQ3_HUMAN" 4 1001.5393 86.92 94865 5993 2 1001.539846 501.7769 Ankyrin repeat domain-containing protein 17 OS=Homo sapiens OX=9606 GN=ANKRD17 PE=1 SV=3 4.79 1558.3 - 2.99E+06 - - - 0.5192 - 1.53 0.07 - 203.9 2 2 1 0.0005 8 0 0 0 1.69E+07 1.94E+05 - - - 0.706 0.9999 221125_WJC_METTL3_EV_vs_WT_F07.05995.05995.2 2.52E-05 18-Dec K.KAPDAEELDK.V "sp|Q9UI42|CBPA4_HUMAN,tr|B7Z5J4|B7Z5J4_HUMAN" 2 1114.5506 5.22 94867 5995 2 1114.551508 558.2826 Carboxypeptidase A4 OS=Homo sapiens OX=9606 GN=CPA4 PE=1 SV=2 4.32 1558.4 - 2.46E+06 - - - 0.7976 - 2.22 0.591 - 449.4 1 2 0 0.0009 10 0 0 0 1.83E+07 3.50E+06 - - - 5.6319 0.9992 221125_WJC_METTL3_EV_vs_WT_F07.05996.05996.2 0.0167 20-Jul R.GSPSTVSSSYK.R "sp|P07197|NFM_HUMAN,tr|E7ESP9|E7ESP9_HUMAN,tr|E7EMV2|E7EMV2_HUMAN" 3 1098.5193 2.61 94868 5996 2 1098.520709 550.2669 Neurofilament medium polypeptide OS=Homo sapiens OX=9606 GN=NEFM PE=1 SV=3 8.59 1558.5 - 2.37E+06 - - - 1.2653 - 1.544 0.374 - 182.6 1 2 0 0.0014 11 0 0 0 1.06E+07 4.06E+06 - - - 2.978 0.9998 221125_WJC_METTL3_EV_vs_WT_F07.05997.05997.3 0.00138 Sep-40 R.IVNTQEQLNHR[166.11].W sp|O15020|SPTN2_HUMAN 1 1360.7087 2.11 94869 5997 3 1360.709295 454.5768 "Spectrin beta chain, non-erythrocytic 2 OS=Homo sapiens OX=9606 GN=SPTBN2 PE=1 SV=3" 6.75 1558.5 - 2.33E+06 - - - 0.4512 - 1.861 0.394 - 122.8 1 2 0 0.0006 11 0 0 0 2.03E+07 9.62E+06 - - - 4.697 0.9688 221125_WJC_METTL3_EV_vs_WT_F07.05998.05998.2 0.00351 14-Sep A.VTYTEHAK.R sp|P62805|H4_HUMAN 1 947.4712 1.12 94870 5998 2 947.471903 474.7429 Histone H4 OS=Homo sapiens OX=9606 GN=H4C1 PE=1 SV=2 6.72 1558.6 - 2.01E+06 - - - 0.6934 - 1.806 0.309 - 289.5 1 1 0 0.0007 8 0 0 0 1.37E+08 1.23E+08 - - - 3.1058 0.9999 221125_WJC_METTL3_EV_vs_WT_F07.05999.05999.2 1.19E-06 13/24 R.ALPNNTSSSPQPK.K "sp|P04637|P53_HUMAN,tr|E7ESS1|E7ESS1_HUMAN,tr|J3KP33|J3KP33_HUMAN,tr|A0A087X1Q1|A0A087X1Q1_HUMAN,tr|A0A0U1RQC9|A0A0U1RQC9_HUMAN,tr|A0A087WT22|A0A087WT22_HUMAN,tr|A0A087WXZ1|A0A087WXZ1_HUMAN" 7 1339.6732 1.07 94871 5999 2 1339.673688 670.8439 Cellular tumor antigen p53 OS=Homo sapiens OX=9606 GN=TP53 PE=1 SV=4 8.8 1558.7 - 1.31E+06 - - - 0.3695 - 2.29 0.587 - 629.2 1 2 0 0.0005 13 0 0 0 2.61E+07 2.45E+07 - - - 5.5029 0.9999 221125_WJC_METTL3_EV_vs_WT_F07.06001.06001.2 2.93E-06 24-Nov R.ALPNNTSSSPQPK[136.11].K "sp|P04637|P53_HUMAN,tr|E7ESS1|E7ESS1_HUMAN,tr|J3KP33|J3KP33_HUMAN,tr|A0A087X1Q1|A0A087X1Q1_HUMAN,tr|A0A0U1RQC9|A0A0U1RQC9_HUMAN,tr|A0A087WT22|A0A087WT22_HUMAN,tr|A0A087WXZ1|A0A087WXZ1_HUMAN" 7 1347.6874 1.07 94873 6001 2 1347.687954 674.851 Cellular tumor antigen p53 OS=Homo sapiens OX=9606 GN=TP53 PE=1 SV=4 8.8 1558.9 - 1.17E+06 - - - 0.4163 - 2.237 0.514 - 424.1 1 2 0 0.0006 13 0 0 0 2.61E+07 2.45E+07 - - - 4.9036 0.9872 221125_WJC_METTL3_EV_vs_WT_F07.06003.06003.2 0.00142 20-Aug K.ETSK[136.11]DTETVLK[136.11].T sp|Q9NP61|ARFG3_HUMAN 1 1265.6686 1.25 94875 6003 2 1265.671704 633.8416 ADP-ribosylation factor GTPase-activating protein 3 OS=Homo sapiens OX=9606 GN=ARFGAP3 PE=1 SV=1 4.68 1559.2 - 857497 - - - 2.4825 - 1.637 0.405 - 151.3 1 2 1 0.0031 11 0 0 0 6.38E+06 5.11E+06 - - - 3.3647 0.9946 221125_WJC_METTL3_EV_vs_WT_F07.06004.06004.2 0.00543 20-Jul R.GSPSTVSSSYK[136.11].R "sp|P07197|NFM_HUMAN,tr|E7ESP9|E7ESP9_HUMAN,tr|E7EMV2|E7EMV2_HUMAN" 3 1106.5335 2.61 94876 6004 2 1106.537315 554.274 Neurofilament medium polypeptide OS=Homo sapiens OX=9606 GN=NEFM PE=1 SV=3 8.59 1559.3 - 822618 - - - 3.4305 - 1.475 0.327 - 90.9 1 2 0 0.0038 11 0 0 0 1.06E+07 4.06E+06 - - - 2.5064 0.9995 221125_WJC_METTL3_EV_vs_WT_F07.06011.06011.2 0.00321 13/14 K.HQQLLEEK[136.11].N sp|P35580|MYH10_HUMAN 1 1031.5491 0.75 94881 6011 2 1031.551374 516.7818 Myosin-10 OS=Homo sapiens OX=9606 GN=MYH10 PE=1 SV=3 5.4 1560.1 - 7.98E+06 - - - 2.1957 - 2.619 0.297 - 676.5 1 2 0 0.0023 8 0 0 0 3.23E+07 4.33E+07 - - - 4.1377 0.96 221125_WJC_METTL3_EV_vs_WT_F07.06012.06012.2 1.72 14-Oct K.HQQLLEEK.N sp|P35580|MYH10_HUMAN 1 1023.5349 0.75 94882 6012 2 1023.540545 512.7747 Myosin-10 OS=Homo sapiens OX=9606 GN=MYH10 PE=1 SV=3 5.4 1560.1 - 7.12E+06 - - - 5.5064 - 2.222 0.08 - 393.7 1 2 0 0.0056 8 0 0 0 3.23E+07 4.33E+07 - - - 2.0381 0.9538 221125_WJC_METTL3_EV_vs_WT_F07.06013.06013.2 0.111 16-Aug D.AVTYTEHAK.R sp|P62805|H4_HUMAN 1 1018.5084 1.45 94883 6013 2 1018.507841 510.2615 Histone H4 OS=Homo sapiens OX=9606 GN=H4C1 PE=1 SV=2 6.79 1560.2 - 4.45E+06 - - - -0.5096 - 1.605 0.295 - 243.8 1 1 0 -0.0005 9 0 0 0 3.37E+07 2.33E+07 - - - 2.5885 0.9996 221125_WJC_METTL3_EV_vs_WT_F07.06014.06014.3 0.0359 Aug-40 R.TLHGQETYTPR.L "sp|Q9BUK6|MSTO1_HUMAN,tr|A0A3B3IUD2|A0A3B3IUD2_HUMAN" 2 1301.6364 1.27 94884 6014 3 1301.635755 434.8861 Protein misato homolog 1 OS=Homo sapiens OX=9606 GN=MSTO1 PE=1 SV=1 6.41 1560.2 - 3.31E+06 - - - -0.5063 - 1.806 0.343 - 131.1 1 2 0 -0.0007 11 0 0 0 3.24E+07 2.55E+07 - - - 4.0432 0.9969 221125_WJC_METTL3_EV_vs_WT_F07.06015.06015.2 9.94E-05 16-Sep K.MKSDSFAPK.T "sp|Q9Y2W1|TR150_HUMAN,tr|A0A3B3ITZ9|A0A3B3ITZ9_HUMAN" 2 1009.4903 1.3 94885 6015 2 1009.489551 505.7524 Thyroid hormone receptor-associated protein 3 OS=Homo sapiens OX=9606 GN=THRAP3 PE=1 SV=2 8.35 1560.3 - 3.29E+06 - - - -0.7093 - 1.565 0.461 - 160.7 1 2 1 -0.0007 9 0 0 0 3.74E+07 2.88E+07 - - - 3.7415 0.9901 221125_WJC_METTL3_EV_vs_WT_F07.06018.06018.3 0.201 14/36 R.LRNDPLNQNK.G "sp|Q9UBB5|MBD2_HUMAN,tr|X6RBL6|X6RBL6_HUMAN" 2 1210.6418 1.78 94888 6018 3 1210.643913 404.5546 Methyl-CpG-binding domain protein 2 OS=Homo sapiens OX=9606 GN=MBD2 PE=1 SV=1 8.75 1560.5 - 1.50E+06 - - - 1.7173 - 2.366 0.184 - 324.9 1 2 1 0.0021 10 0 0 0 1.36E+07 7.61E+06 - - - 3.1059 0.9997 221125_WJC_METTL3_EV_vs_WT_F07.06021.06021.2 0.000316 20-Sep R.SQQQPTPVTPK.K "sp|O95251|KAT7_HUMAN,tr|A0A6Q8PHH2|A0A6Q8PHH2_HUMAN" 2 1209.6354 1.08 94891 6021 2 1209.634385 605.825 Histone acetyltransferase KAT7 OS=Homo sapiens OX=9606 GN=KAT7 PE=1 SV=1 8.47 1560.9 - 833149 - - - -0.7986 - 1.755 0.443 - 389.1 1 2 0 -0.001 11 0 0 0 8.19E+06 7.55E+06 - - - 3.8343 0.9881 221125_WJC_METTL3_EV_vs_WT_F07.06022.06022.2 1.95E-06 16-Nov A.HQNLVTGVK.F sp|O43172|PRP4_HUMAN 1 994.556 13.43 94892 6022 2 994.556761 498.2853 U4\U6 small nuclear ribonucleoprotein Prp4 OS=Homo sapiens OX=9606 GN=PRPF4 PE=1 SV=2 8.76 1561 - 598911 - - - 0.7863 - 2.015 0.444 - 309.4 1 1 0 0.0008 9 0 0 0 2.62E+06 1.95E+05 - - - 4.3471 0.9994 221125_WJC_METTL3_EV_vs_WT_F07.06025.06025.2 0.00588 20-Aug R.TLHGQETYTPR.L "sp|Q9BUK6|MSTO1_HUMAN,tr|A0A3B3IUD2|A0A3B3IUD2_HUMAN" 2 1301.6364 2.82 94895 6025 2 1301.637564 651.8255 Protein misato homolog 1 OS=Homo sapiens OX=9606 GN=MSTO1 PE=1 SV=1 6.41 1561.4 - 307969 - - - 0.8835 - 1.404 0.411 - 192.3 1 2 0 0.0011 11 0 0 0 3.07E+06 1.09E+06 - - - 2.9942 0.9998 221125_WJC_METTL3_EV_vs_WT_F07.06028.06028.2 1.07E-06 18-Nov R.DAVTYTEHAK.R sp|P62805|H4_HUMAN 1 1133.5353 1.06 94896 6028 2 1133.535287 567.7749 Histone H4 OS=Homo sapiens OX=9606 GN=H4C1 PE=1 SV=2 5.32 1561.8 - 1.43E+08 - - - -0.0141 - 2.354 0.349 - 541.6 1 2 0 0 10 0 0 0 8.81E+08 8.32E+08 - - - 4.0084 0.9935 221125_WJC_METTL3_EV_vs_WT_F07.06032.06032.2 0.477 14-Oct R.QNINKFER.R "sp|O95785|WIZ_HUMAN,tr|A0A669KBG4|A0A669KBG4_HUMAN,tr|A0A2R8YFV2|A0A2R8YFV2_HUMAN,tr|A0A669KAV7|A0A669KAV7_HUMAN,tr|M0QXA7|M0QXA7_HUMAN,tr|A0A669KBH9|A0A669KBH9_HUMAN,tr|B9EGQ5|B9EGQ5_HUMAN" 7 1047.5461 1.12 94900 6032 2 1047.544496 524.7803 Protein Wiz OS=Homo sapiens OX=9606 GN=WIZ PE=1 SV=2 8.75 1562.2 - 660274 - - - -1.5713 - 1.95 0.314 - 466.6 1 2 1 -0.0016 8 0 0 0 5.75E+06 5.15E+06 - - - 3.3738 0.9997 221125_WJC_METTL3_EV_vs_WT_F07.06033.06033.2 0.000223 26-Sep K.ASPSTAGETPSGVK.R "sp|Q9UI10|EI2BD_HUMAN,tr|A0A087WW69|A0A087WW69_HUMAN,tr|A0A087WTA5|A0A087WTA5_HUMAN,tr|F8W8L6|F8W8L6_HUMAN,tr|E7ERK9|E7ERK9_HUMAN" 5 1287.6307 0.87 94901 6033 2 1287.631186 644.8226 Translation initiation factor eIF-2B subunit delta OS=Homo sapiens OX=9606 GN=EIF2B4 PE=1 SV=2 6.05 1562.3 - 623958 - - - 0.4085 - 1.81 0.428 - 256.6 1 2 0 0.0005 14 0 0 0 7.87E+06 9.00E+06 - - - 3.691 0.9977 221125_WJC_METTL3_EV_vs_WT_F07.06035.06035.2 0.000142 22-Aug K.TIINADKDGDGR.L "sp|P63098|CANB1_HUMAN,tr|D3YTA9|D3YTA9_HUMAN,tr|H7BYZ3|H7BYZ3_HUMAN,tr|F6U1T9|F6U1T9_HUMAN" 4 1273.6262 3.12 94903 6035 2 1273.625067 637.8204 Calcineurin subunit B type 1 OS=Homo sapiens OX=9606 GN=PPP3R1 PE=1 SV=2 4.43 1562.6 - 294092 - - - -0.9233 - 1.772 0.498 - 166.7 1 2 1 -0.0012 12 0 0 0 2.04E+06 6.53E+05 - - - 4.2242 0.997 221125_WJC_METTL3_EV_vs_WT_F07.06037.06037.2 0.0017 16-Sep K.GKLDDYQER.M "sp|Q14444|CAPR1_HUMAN,tr|E9PLA9|E9PLA9_HUMAN" 2 1122.5306 0.06 94904 6037 2 1122.529252 562.2726 Caprin-1 OS=Homo sapiens OX=9606 GN=CAPRIN1 PE=1 SV=2 4.56 1562.8 - 2.07E+06 - - - -1.1581 - 1.842 0.437 - 252 1 2 1 -0.0013 9 0 0 0 1.92E+07 3.39E+08 - - - 4.0355 0.9996 221125_WJC_METTL3_EV_vs_WT_F07.06039.06039.3 0.00118 Sep-40 K.VIQENEHALQK[136.11].D "sp|Q9NTJ3|SMC4_HUMAN,tr|E9PD53|E9PD53_HUMAN" 2 1315.6976 0.78 94905 6039 3 1315.698179 439.5731 Structural maintenance of chromosomes protein 4 OS=Homo sapiens OX=9606 GN=SMC4 PE=1 SV=2 5.4 1563 - 2.76E+06 - - - 0.4674 - 1.685 0.364 - 85.7 1 2 0 0.0006 11 0 0 0 1.90E+07 2.43E+07 - - - 4.0803 0.9994 221125_WJC_METTL3_EV_vs_WT_F07.06041.06041.3 0.00387 Sep-36 R.YNGEPEHIER.N "sp|Q14739|LBR_HUMAN,tr|A0A494C1L1|A0A494C1L1_HUMAN,tr|C9JXK0|C9JXK0_HUMAN" 3 1242.5629 1.09 94906 6041 3 1242.561408 415.1949 Delta(14)-sterol reductase LBR OS=Homo sapiens OX=9606 GN=LBR PE=1 SV=2 4.75 1563.1 - 2.63E+06 - - - -1.2128 - 1.812 0.312 - 96.5 1 2 0 -0.0015 10 0 0 0 3.41E+07 3.13E+07 - - - 3.7541 0.9998 221125_WJC_METTL3_EV_vs_WT_F07.06043.06043.2 3.61E-05 18-Oct K.TDSPSC[160.03]EYSR[166.11].F sp|Q9HAV4|XPO5_HUMAN 1 1210.48 0.83 94908 6043 2 1210.479589 606.2473 Exportin-5 OS=Homo sapiens OX=9606 GN=XPO5 PE=1 SV=1 4.37 1563.4 - 763563 - - - -0.3288 - 1.986 0.405 - 459.4 1 2 0 -0.0004 10 0 0 0 6.04E+06 7.28E+06 - - - 3.9474 0.9998 221125_WJC_METTL3_EV_vs_WT_F07.06050.06050.2 7.37E-06 22-Sep K.EEPSVAPSSTGK.T sp|Q8N183|NDUF2_HUMAN 1 1187.567 2.29 94913 6050 2 1187.566924 594.7908 NADH dehydrogenase [ubiquinone] 1 alpha subcomplex assembly factor 2 OS=Homo sapiens OX=9606 GN=NDUFAF2 PE=1 SV=1 4.53 1564.3 - 1.84E+06 - - - -0.0615 - 1.864 0.491 - 278.4 1 2 0 -0.0001 12 0 0 0 1.55E+07 6.75E+06 - - - 4.306 0.8267 221125_WJC_METTL3_EV_vs_WT_F07.06053.06053.2 0.899 16-Jun S.TC[160.03]DHGIVAK.L "sp|O60832|DKC1_HUMAN,tr|H7C2Q2|H7C2Q2_HUMAN" 2 999.4808 0.48 94916 6053 2 999.480825 500.7477 H\ACA ribonucleoprotein complex subunit DKC1 OS=Homo sapiens OX=9606 GN=DKC1 PE=1 SV=3 6.4 1564.5 - 1.43E+06 - - - 0.06 - 1.19 0.247 - 145 1 1 0 0.0001 9 0 0 0 1.17E+07 2.42E+07 - - - 1.3686 0.9997 221125_WJC_METTL3_EV_vs_WT_F07.06054.06054.2 0.00217 22-Sep K.EEPSVAPSSTGK[136.11].T sp|Q8N183|NDUF2_HUMAN 1 1195.5812 2.29 94917 6054 2 1195.582295 598.7979 NADH dehydrogenase [ubiquinone] 1 alpha subcomplex assembly factor 2 OS=Homo sapiens OX=9606 GN=NDUFAF2 PE=1 SV=1 4.53 1564.6 - 966429 - - - 0.9184 - 1.779 0.439 - 286.7 1 2 0 0.0011 12 0 0 0 1.55E+07 6.75E+06 - - - 3.7988 0.997 221125_WJC_METTL3_EV_vs_WT_F07.06056.06056.2 0.173 14-Aug R.RTTWAEER.K sp|Q9BX40|LS14B_HUMAN 1 1047.5098 1.41 94919 6056 2 1047.508285 524.7622 Protein LSM14 homolog B OS=Homo sapiens OX=9606 GN=LSM14B PE=1 SV=1 6.14 1564.9 - 526450 - - - -1.4052 - 1.702 0.154 - 197.6 1 2 0 -0.0015 8 0 0 0 9.56E+06 6.78E+06 - - - 1.7819 1 221125_WJC_METTL3_EV_vs_WT_F07.06057.06057.2 7.70E-06 15/30 R.GPAAAQGSAAAPAEPK.L sp|Q9UHD9|UBQL2_HUMAN 1 1392.6997 1.25 94920 6057 2 1392.700349 697.3571 Ubiquilin-2 OS=Homo sapiens OX=9606 GN=UBQLN2 PE=1 SV=2 6 1565 - 525686 - - - 0.4351 - 3.383 0.536 - 770.7 1 2 0 0.0006 16 0 0 0 3.17E+06 2.53E+06 - - - 5.9961 1 221125_WJC_METTL3_EV_vs_WT_F07.06058.06058.2 8.17E-12 16/30 R.GPAAAQGSAAAPAEPK[136.11].L sp|Q9UHD9|UBQL2_HUMAN 1 1400.7139 1.59 94921 6058 2 1400.71395 701.3642 Ubiquilin-2 OS=Homo sapiens OX=9606 GN=UBQLN2 PE=1 SV=2 6 1565.1 - 363065 - - - 0.005 - 3.101 0.614 - 894.3 1 2 0 0 16 0 0 0 6.07E+06 3.83E+06 - - - 6.3584 0.8775 221125_WJC_METTL3_EV_vs_WT_F07.06059.06059.2 2.32 20-May R.ESHTAVVYTEK.D "sp|P51610|HCFC1_HUMAN,tr|A6NEM2|A6NEM2_HUMAN" 2 1262.6143 0.67 94922 6059 2 1262.614127 632.3144 Host cell factor 1 OS=Homo sapiens OX=9606 GN=HCFC1 PE=1 SV=2 5.4 1565.2 - 295798 - - - -0.1228 - 0.928 0.045 - 55.9 3 2 0 -0.0002 11 0 0 0 2.20E+06 3.31E+06 - - - -1.042 0.9934 221125_WJC_METTL3_EV_vs_WT_F07.06064.06064.2 0.00991 24-May R.AAQAGPTQPGPPR[166.11].S "sp|Q9BUL5|PHF23_HUMAN,tr|A0A087WVQ2|A0A087WVQ2_HUMAN,tr|I3L4Q4|I3L4Q4_HUMAN,tr|I3L0Y2|I3L0Y2_HUMAN" 4 1256.6501 0.12 94927 6064 2 1256.648501 629.3323 PHD finger protein 23 OS=Homo sapiens OX=9606 GN=PHF23 PE=1 SV=1 9.79 1565.9 - 202373 - - - -1.2756 - 1.316 0.223 - 66.4 4 2 0 -0.0016 13 0 0 0 1.66E+05 1.43E+06 - - - 1.1234 0.974 221125_WJC_METTL3_EV_vs_WT_F07.06066.06066.3 0.157 Sep-36 R.NTPYQAPVRR.Q sp|P49790|NU153_HUMAN 1 1200.6364 1.25 94928 6066 3 1200.63864 401.2194 Nuclear pore complex protein Nup153 OS=Homo sapiens OX=9606 GN=NUP153 PE=1 SV=2 10.84 1566.1 - 2.95E+06 - - - 1.904 - 1.547 0.159 - 131.7 1 2 0 0.0023 10 0 0 0 9.33E+07 7.47E+07 - - - 1.5863 0.999 221125_WJC_METTL3_EV_vs_WT_F07.06067.06067.2 0.00245 20-Aug R.QPAPPTSQPPR.A "sp|Q9BUT9|MCRI2_HUMAN,tr|I3L172|I3L172_HUMAN" 2 1174.6095 0.4 94929 6067 2 1174.610865 588.312 MAPK regulated corepressor interacting protein 2 OS=Homo sapiens OX=9606 GN=MCRIP2 PE=1 SV=2 9.75 1566.2 - 259124 - - - 1.1868 - 1.412 0.376 - 160.8 1 2 0 0.0014 11 0 0 0 8.08E+06 2.02E+07 - - - 2.751 0.9951 221125_WJC_METTL3_EV_vs_WT_F07.06068.06068.2 0.00767 14-Sep R.LSK[136.11]EDIER[166.11].M "sp|P11142|HSP7C_HUMAN,tr|E9PNE6|E9PNE6_HUMAN,tr|A8K7Q2|A8K7Q2_HUMAN,tr|E9PKE3|E9PKE3_HUMAN,tr|E9PM13|E9PM13_HUMAN,tr|E9PS65|E9PS65_HUMAN" 6 1006.5414 0.16 94930 6068 2 1006.542567 504.278 Heat shock cognate 71 kDa protein OS=Homo sapiens OX=9606 GN=HSPA8 PE=1 SV=1 4.68 1566.3 - 4.73E+06 - - - 1.1644 - 1.854 0.358 - 369.2 1 2 1 0.0012 8 0 0 0 4.95E+07 3.15E+08 - - - 3.5467 0.9999 221125_WJC_METTL3_EV_vs_WT_F07.06070.06070.3 5.27E-05 Nov-48 R.ATAPQTQHVSPMR[166.11].Q "sp|P29692|EF1D_HUMAN,tr|E9PI39|E9PI39_HUMAN,tr|E9PQ49|E9PQ49_HUMAN,tr|A0A087X1X7|A0A087X1X7_HUMAN,tr|E9PL12|E9PL12_HUMAN,tr|E9PQZ1|E9PQZ1_HUMAN,tr|E9PK06|E9PK06_HUMAN,tr|E9PPR1|E9PPR1_HUMAN,tr|E9PRY8|E9PRY8_HUMAN,tr|E9PK01|E9PK01_HUMAN,tr|E9PL71|E9PL71_HUMAN" 11 1432.7121 2.91 94932 6070 3 1432.714489 478.578 Elongation factor 1-delta OS=Homo sapiens OX=9606 GN=EEF1D PE=1 SV=5 9.8 1566.4 - 1.93E+06 - - - 1.701 - 2.292 0.449 - 163 1 2 0 0.0024 13 0 0 0 1.09E+08 3.77E+07 - - - 5.794 0.9714 221125_WJC_METTL3_EV_vs_WT_F07.06085.06085.2 0.265 14-Jul R.LSKEDIER.M "sp|P11142|HSP7C_HUMAN,tr|E9PNE6|E9PNE6_HUMAN,tr|A8K7Q2|A8K7Q2_HUMAN,tr|E9PKE3|E9PKE3_HUMAN,tr|E9PM13|E9PM13_HUMAN,tr|E9PS65|E9PS65_HUMAN" 6 988.5189 0.16 94946 6085 2 988.521002 495.2667 Heat shock cognate 71 kDa protein OS=Homo sapiens OX=9606 GN=HSPA8 PE=1 SV=1 4.68 1568 - 855207 - - - 2.1011 - 1.454 0.291 - 225.6 1 2 1 0.0021 8 0 0 0 4.82E+07 3.05E+08 - - - 2.3186 0.9999 221125_WJC_METTL3_EV_vs_WT_F07.06086.06086.2 2.00E-06 14/24 K.TSSEASVSSSVAK[136.11].N sp|Q9NXV6|CARF_HUMAN 1 1246.6132 1.4 94947 6086 2 1246.611727 624.3139 CDKN2A-interacting protein OS=Homo sapiens OX=9606 GN=CDKN2AIP PE=1 SV=3 5.66 1568.1 - 521794 - - - -1.2017 - 2.874 0.453 - 951.2 1 2 0 -0.0015 13 0 0 0 7.27E+06 5.21E+06 - - - 5.0959 0.9989 221125_WJC_METTL3_EV_vs_WT_F07.06089.06089.2 0.00132 18-Aug K.C[160.03]SSTPDNLSR[166.11].T sp|Q5T5Y3|CAMP1_HUMAN 1 1145.5011 67.5 94950 6089 2 1145.504527 573.7578 Calmodulin-regulated spectrin-associated protein 1 OS=Homo sapiens OX=9606 GN=CAMSAP1 PE=1 SV=2 5.83 1568.5 - 244477 - - - 3.0301 - 1.41 0.517 - 167.1 1 2 0 0.0035 10 0 0 0 8.14E+07 1.21E+06 - - - 3.8175 0.9712 221125_WJC_METTL3_EV_vs_WT_F07.06093.06093.3 0.176 Sep-40 R.GK[136.11]DC[160.03]AVIVTQK[136.11].K "sp|P60900|PSA6_HUMAN,tr|G3V5Z7|G3V5Z7_HUMAN,tr|G3V295|G3V295_HUMAN,tr|G3V3I1|G3V3I1_HUMAN,tr|G3V3U4|G3V3U4_HUMAN" 5 1233.6722 1.23 94952 6093 3 1233.672736 412.2313 Proteasome subunit alpha type-6 OS=Homo sapiens OX=9606 GN=PSMA6 PE=1 SV=1 8.2 1569.1 - 1.16E+06 - - - 0.428 - 1.586 0.2 - 108.4 1 2 1 0.0005 11 0 0 0 2.74E+07 2.23E+07 - - - 2.0799 0.8408 221125_WJC_METTL3_EV_vs_WT_F07.06094.06094.2 0.311 16-Sep K.DVFQHSQSR[166.11].T "sp|Q9NZB2|F120A_HUMAN,tr|A0A0C4DH52|A0A0C4DH52_HUMAN" 2 1112.5238 0.65 94953 6094 2 1113.528683 557.2692 Constitutive coactivator of PPAR-gamma-like protein 1 OS=Homo sapiens OX=9606 GN=FAM120A PE=1 SV=2 6.74 1569.2 - 700346 - - - 903.2094 - 1.471 0.224 - 310.8 1 2 0 1.0048 9 0 0 0 1.59E+07 2.45E+07 - - - 1.4965 0.8531 221125_WJC_METTL3_EV_vs_WT_F07.06095.06095.2 4.11 14-Jun R.TSIEVGVK.G sp|Q03052|PO3F1_HUMAN 1 831.4702 65943.21 94954 6095 2 831.471603 416.7424 "POU domain, class 3, transcription factor 1 OS=Homo sapiens OX=9606 GN=POU3F1 PE=2 SV=3" 5.66 1569.2 - 2.19E+06 - - - 1.7078 - 1.109 0.003 - 133.6 2 2 0 0.0014 8 0 0 0 1.70E+09 2.58E+04 - - - -0.7597 0.9999 221125_WJC_METTL3_EV_vs_WT_F07.06104.06104.2 4.55E-05 24-Dec K.TSSEASVSSSVAK.N sp|Q9NXV6|CARF_HUMAN 1 1238.599 1.52 94961 6104 2 1238.599062 620.3068 CDKN2A-interacting protein OS=Homo sapiens OX=9606 GN=CDKN2AIP PE=1 SV=3 5.66 1570.4 - 495157 - - - 0.0299 - 2.175 0.481 - 510.4 1 2 0 0 13 0 0 0 7.93E+06 5.21E+06 - - - 4.5879 0.9993 221125_WJC_METTL3_EV_vs_WT_F07.06106.06106.2 0.00215 16-Nov R.KDDEVQVVR.G "sp|Q9UNX3|RL26L_HUMAN,sp|P61254|RL26_HUMAN,tr|J3QQQ9|J3QQQ9_HUMAN,tr|E5RIT6|E5RIT6_HUMAN,tr|J3QQV1|J3QQV1_HUMAN,tr|J3QRC4|J3QRC4_HUMAN,tr|J3QRI7|J3QRI7_HUMAN" 7 1086.5669 1.01 94963 6106 2 1086.568044 544.2907 60S ribosomal protein L26-like 1 OS=Homo sapiens OX=9606 GN=RPL26L1 PE=1 SV=1 4.56 1570.7 - 403226 - - - 1.0188 - 2.061 0.253 - 451.9 1 2 0 0.0011 9 0 0 0 9.68E+07 9.61E+07 - - - 3.0015 0.9997 221125_WJC_METTL3_EV_vs_WT_F07.06108.06108.3 0.00336 Nov-36 K.KPITEIQDSK.D "sp|O15381|NVL_HUMAN,tr|E9PH71|E9PH71_HUMAN,tr|C9J6P7|C9J6P7_HUMAN,tr|C9JP83|C9JP83_HUMAN" 4 1157.6292 1.32 94965 6108 3 1157.629597 386.8837 Nuclear valosin-containing protein-like OS=Homo sapiens OX=9606 GN=NVL PE=1 SV=1 6.07 1570.9 - 311934 - - - 0.3404 - 2.021 0.321 - 191 1 2 0 0.0004 10 0 0 0 2.09E+07 1.58E+07 - - - 4.1735 0.9996 221125_WJC_METTL3_EV_vs_WT_F07.06110.06110.2 0.00122 16-Jul R.QNLHEIGER.C tr|F8W0Q9|F8W0Q9_HUMAN 1 1094.5469 999 94967 6110 2 1094.546912 548.2807 Periphilin-1 OS=Homo sapiens OX=9606 GN=PPHLN1 PE=1 SV=1 5.4 1571.2 - 201911 - - - 0.0375 - 1.569 0.412 - 234.8 1 2 0 0 9 0 0 0 4.75E+06 0.00E+00 - - - 3.3872 0.9996 221125_WJC_METTL3_EV_vs_WT_F07.06111.06111.2 0.0042 18-Sep K.KPITEIQDSK.D "sp|O15381|NVL_HUMAN,tr|E9PH71|E9PH71_HUMAN,tr|C9J6P7|C9J6P7_HUMAN,tr|C9JP83|C9JP83_HUMAN" 4 1157.6292 1.24 94968 6111 2 1157.628739 579.8219 Nuclear valosin-containing protein-like OS=Homo sapiens OX=9606 GN=NVL PE=1 SV=1 6.07 1571.3 - 171670 - - - -0.4008 - 1.801 0.352 - 264 1 2 0 -0.0005 10 0 0 0 1.12E+07 9.06E+06 - - - 3.283 0.9962 221125_WJC_METTL3_EV_vs_WT_F07.06114.06114.2 0.231 14-Apr R.RPFDPNDR.C "sp|Q16629|SRSF7_HUMAN,tr|C9JAB2|C9JAB2_HUMAN,tr|F8WEA1|F8WEA1_HUMAN,tr|A0A0B4J1Z1|A0A0B4J1Z1_HUMAN" 4 1015.4835 1.43 94969 6114 2 1015.485247 508.749 Serine\arginine-rich splicing factor 7 OS=Homo sapiens OX=9606 GN=SRSF7 PE=1 SV=1 5.96 1571.7 - 478529 - - - 1.679 - 1.254 0.331 - 67.2 7 2 0 0.0017 8 0 0 0 8.60E+07 6.03E+07 - - - 1.7904 0.9987 221125_WJC_METTL3_EV_vs_WT_F07.06118.06118.2 0.00776 18-Aug K.K[136.11]PITEIQDSK[136.11].D "sp|O15381|NVL_HUMAN,tr|E9PH71|E9PH71_HUMAN,tr|C9J6P7|C9J6P7_HUMAN,tr|C9JP83|C9JP83_HUMAN" 4 1173.6576 1.24 94973 6118 2 1173.657337 587.8361 Nuclear valosin-containing protein-like OS=Homo sapiens OX=9606 GN=NVL PE=1 SV=1 6.07 1572.2 - 216726 - - - -0.2266 - 1.448 0.28 - 144.1 1 2 0 -0.0003 10 0 0 0 1.12E+07 9.06E+06 - - - 2.1423 0.9532 221125_WJC_METTL3_EV_vs_WT_F07.06122.06122.2 0.0088 16-Nov S.RTSFTSVSR.S "sp|P13647|K2C5_HUMAN,tr|F8VV57|F8VV57_HUMAN,tr|F8VU69|F8VU69_HUMAN" 3 1039.5411 999 94976 6122 2 1039.542776 520.7778 "Keratin, type II cytoskeletal 5 OS=Homo sapiens OX=9606 GN=KRT5 PE=1 SV=3" 12 1572.7 - 2.71E+06 - - - 1.6536 - 2.02 0.283 - 179.4 1 1 0 0.0017 9 0 0 0 2.07E+08 0.00E+00 - - - 3.1648 0.9987 221125_WJC_METTL3_EV_vs_WT_F07.06124.06124.2 0.000111 18-Nov R.LQNSYQPTNK.G "sp|Q7L014|DDX46_HUMAN,tr|A0A0C4DG89|A0A0C4DG89_HUMAN,tr|H0Y9U3|H0Y9U3_HUMAN" 3 1191.5884 2.26 94977 6124 2 1191.590813 596.8015 Probable ATP-dependent RNA helicase DDX46 OS=Homo sapiens OX=9606 GN=DDX46 PE=1 SV=2 8.59 1572.9 - 798413 - - - 2.0242 - 2.03 0.257 - 412.9 1 2 0 0.0024 10 0 0 0 7.16E+07 3.17E+07 - - - 2.9148 0.9986 221125_WJC_METTL3_EV_vs_WT_F07.06137.06137.2 5.12E-06 24-Aug R.FSSSSGYGGGSSR.V sp|P35527|K1C9_HUMAN 1 1234.5214 255.87 94985 6137 2 1234.5242 618.268 "Keratin, type I cytoskeletal 9 OS=Homo sapiens OX=9606 GN=KRT9 PE=1 SV=3" 8.75 1574.7 - 182197 - - - 2.2324 - 1.806 0.332 - 159.8 1 2 0 0.0028 13 0 0 0 1.59E+07 6.20E+04 - - - 3.0094 0.9901 221125_WJC_METTL3_EV_vs_WT_F07.06140.06140.3 0.105 Sep-32 K.GK[136.11]LDDYQER[166.11].M "sp|Q14444|CAPR1_HUMAN,tr|E9PLA9|E9PLA9_HUMAN" 2 1140.553 0.001 94987 6140 3 1140.554602 381.1916 Caprin-1 OS=Homo sapiens OX=9606 GN=CAPRIN1 PE=1 SV=2 4.56 1574.9 - 2.54E+06 - - - 1.3853 - 1.807 0.238 - 114.7 1 2 1 0.0016 9 0 0 0 0.00E+00 1.17E+08 - - - 2.9762 0.9738 221125_WJC_METTL3_EV_vs_WT_F07.06152.06152.2 0.0951 16-Sep K.TKDQILTSR.L "sp|Q86XL3|ANKL2_HUMAN,tr|F5H1D4|F5H1D4_HUMAN" 2 1060.5877 1.65 94991 6152 2 1060.587776 531.3011 Ankyrin repeat and LEM domain-containing protein 2 OS=Homo sapiens OX=9606 GN=ANKLE2 PE=1 SV=4 8.41 1576.6 - 287513 - - - 0.0971 - 1.33 0.242 - 234.1 1 2 1 0.0001 9 0 0 0 1.28E+07 7.75E+06 - - - 1.6534 0.9991 221125_WJC_METTL3_EV_vs_WT_F07.06170.06170.2 0.00432 20-Sep K.EQSQLTATQTR.T sp|Q6P2Q9|PRP8_HUMAN 1 1261.6262 1.37 94996 6170 2 1261.628306 631.8204 Pre-mRNA-processing-splicing factor 8 OS=Homo sapiens OX=9606 GN=PRPF8 PE=1 SV=2 6.1 1579 - 382494 - - - 1.6352 - 1.693 0.357 - 288.9 1 2 0 0.0021 11 0 0 0 1.26E+08 9.17E+07 - - - 3.1015 0.9994 221125_WJC_METTL3_EV_vs_WT_F07.06176.06176.2 0.00297 16-Sep K.TIAPQNAPR.D "sp|Q9NYF8|BCLF1_HUMAN,tr|H0YF00|H0YF00_HUMAN,tr|E9PKI6|E9PKI6_HUMAN,tr|A0A1W2PQ43|A0A1W2PQ43_HUMAN,tr|E9PK91|E9PK91_HUMAN,tr|E9PJA7|E9PJA7_HUMAN,tr|E9PK09|E9PK09_HUMAN,tr|E9PQN2|E9PQN2_HUMAN" 8 966.5247 2.11 94999 6176 2 966.525945 484.2696 Bcl-2-associated transcription factor 1 OS=Homo sapiens OX=9606 GN=BCLAF1 PE=1 SV=2 9.41 1579.8 - 364696 - - - 1.3098 - 1.598 0.384 - 211.4 1 2 0 0.0013 9 0 0 0 6.94E+07 3.29E+07 - - - 3.233 0.9999 221125_WJC_METTL3_EV_vs_WT_F07.06184.06184.3 2.70E-05 Oct-40 R.TLHGQETYTPR[166.11].L "sp|Q9BUK6|MSTO1_HUMAN,tr|A0A3B3IUD2|A0A3B3IUD2_HUMAN" 2 1311.6447 1.33 95003 6184 3 1311.645896 438.2222 Protein misato homolog 1 OS=Homo sapiens OX=9606 GN=MSTO1 PE=1 SV=1 6.41 1580.8 - 761032 - - - 0.924 - 1.984 0.473 - 184.4 1 2 0 0.0012 11 0 0 0 9.53E+07 7.18E+07 - - - 5.7594 0.9999 221125_WJC_METTL3_EV_vs_WT_F07.06186.06186.2 0.00479 13/18 K.KDVDGAYMTK.V sp|P04264|K2C1_HUMAN 1 1126.5329 40.55 95005 6186 2 1126.532154 564.2737 "Keratin, type II cytoskeletal 1 OS=Homo sapiens OX=9606 GN=KRT1 PE=1 SV=6" 5.96 1581.1 - 334547 - - - -0.6267 - 2.346 0.545 - 521.9 1 2 0 -0.0007 10 0 0 0 1.51E+08 3.73E+06 - - - 5.4463 0.9998 221125_WJC_METTL3_EV_vs_WT_F07.06191.06191.2 0.00252 20-Aug K.EQSQLTATQTR[166.11].T sp|Q6P2Q9|PRP8_HUMAN 1 1271.6345 1.37 95008 6191 2 1271.635131 636.8245 Pre-mRNA-processing-splicing factor 8 OS=Homo sapiens OX=9606 GN=PRPF8 PE=1 SV=2 6.1 1581.7 - 759821 - - - 0.486 - 1.84 0.442 - 260.7 1 2 0 0.0006 11 0 0 0 1.26E+08 9.17E+07 - - - 3.955 0.975 221125_WJC_METTL3_EV_vs_WT_F07.06198.06198.2 0.15 20-Jun K.SSAQGKPLALK.V sp|P46060|RAGP1_HUMAN 1 1098.6397 1.18 95013 6198 2 1098.640223 550.3271 Ran GTPase-activating protein 1 OS=Homo sapiens OX=9606 GN=RANGAP1 PE=1 SV=1 10 1582.7 - 199828 - - - 0.4688 - 0.974 0.148 - 69.2 1 2 0 0.0005 11 0 0 0 1.16E+07 9.80E+06 - - - 0.0627 0.9936 221125_WJC_METTL3_EV_vs_WT_F07.06203.06203.2 0.0553 16-Jul K.TIAPQNAPR[166.11].D "sp|Q9NYF8|BCLF1_HUMAN,tr|H0YF00|H0YF00_HUMAN,tr|E9PKI6|E9PKI6_HUMAN,tr|A0A1W2PQ43|A0A1W2PQ43_HUMAN,tr|E9PK91|E9PK91_HUMAN,tr|E9PJA7|E9PJA7_HUMAN,tr|E9PK09|E9PK09_HUMAN,tr|E9PQN2|E9PQN2_HUMAN" 8 976.5329 1.85 95015 6203 2 976.535111 489.2738 Bcl-2-associated transcription factor 1 OS=Homo sapiens OX=9606 GN=BCLAF1 PE=1 SV=2 9.41 1583.3 - 349992 - - - 2.214 - 1.314 0.246 - 152.7 1 2 0 0.0022 9 0 0 0 3.28E+07 1.78E+07 - - - 1.6473 0.9997 221125_WJC_METTL3_EV_vs_WT_F07.06207.06207.2 2.57E-07 13/18 R.THTAFPGTDK.L sp|Q96F45|ZN503_HUMAN 1 1073.5142 1.39 95017 6207 2 1073.515674 537.7644 Zinc finger protein 503 OS=Homo sapiens OX=9606 GN=ZNF503 PE=1 SV=1 6.41 1583.8 - 636366 - - - 1.3973 - 2.373 0.378 - 720.2 1 2 0 0.0015 10 0 0 0 5.58E+08 4.01E+08 - - - 4.2446 0.9996 221125_WJC_METTL3_EV_vs_WT_F07.06208.06208.2 4.39E-06 18-Oct R.THTAFPGTDK[136.11].L sp|Q96F45|ZN503_HUMAN 1 1081.5284 1.39 95018 6208 2 1081.526072 541.7715 Zinc finger protein 503 OS=Homo sapiens OX=9606 GN=ZNF503 PE=1 SV=1 6.41 1583.9 - 481199 - - - -2.1285 - 2.235 0.39 - 328.5 1 2 0 -0.0023 10 0 0 0 5.58E+08 4.01E+08 - - - 4.1657 0.9999 221125_WJC_METTL3_EV_vs_WT_F07.06219.06219.2 0.000128 22-Nov K.LSNSDSQDIQGR[166.11].N sp|O14545|TRAD1_HUMAN 1 1328.6196 0.52 95026 6219 2 1328.619583 665.3171 TRAF-type zinc finger domain-containing protein 1 OS=Homo sapiens OX=9606 GN=TRAFD1 PE=1 SV=1 4.21 1585.2 - 85255.3 - - - -0.0068 - 2.312 0.543 - 589.9 1 2 0 0 12 0 0 0 8.22E+06 1.59E+07 - - - 5.2568 0.9971 221125_WJC_METTL3_EV_vs_WT_F07.06223.06223.2 0.107 16-Jul K.DSSGWSSSK.D "sp|O00571|DDX3X_HUMAN,tr|A0A2R8YFR4|A0A2R8YFR4_HUMAN,tr|A0A2R8YCW1|A0A2R8YCW1_HUMAN,tr|A0A2R8YDH3|A0A2R8YDH3_HUMAN,tr|A0A2R8Y645|A0A2R8Y645_HUMAN,tr|A0A2R8YF78|A0A2R8YF78_HUMAN,tr|A0A2R8YCU0|A0A2R8YCU0_HUMAN,tr|A0A0D9SFB3|A0A0D9SFB3_HUMAN,tr|A0A2R8YFS5|A0A2R8YFS5_HUMAN,tr|A0A0D9SF53|A0A0D9SF53_HUMAN,tr|A0A2R8Y650|A0A2R8Y650_HUMAN,tr|A0A087WX09|A0A087WX09_HUMAN,tr|A0A2R8Y5G6|A0A2R8Y5G6_HUMAN,tr|A0A0D9SG12|A0A0D9SG12_HUMAN,tr|F6S8Q4|F6S8Q4_HUMAN,tr|A0A2U3TZJ9|A0A2U3TZJ9_HUMAN,tr|A0A2R8Y4A4|A0A2R8Y4A4_HUMAN,tr|A0A2R8YF89|A0A2R8YF89_HUMAN" 18 939.3934 1.12 95028 6223 2 939.394923 470.704 ATP-dependent RNA helicase DDX3X OS=Homo sapiens OX=9606 GN=DDX3X PE=1 SV=3 5.84 1585.8 - 1.26E+06 - - - 1.6319 - 1.557 0.226 - 214 1 2 0 0.0015 9 0 0 0 2.07E+08 1.85E+08 - - - 1.9907 0.9997 221125_WJC_METTL3_EV_vs_WT_F07.06224.06224.2 0.000469 Apr-32 R.AGQSAAGAAPGGGVDTR[166.11].D "sp|P21333|FLNA_HUMAN,tr|A0A7P0NMY4|A0A7P0NMY4_HUMAN,tr|A0A7I2V3E6|A0A7I2V3E6_HUMAN,tr|A0A087WWY3|A0A087WWY3_HUMAN" 4 1451.6992 1.22 95029 6224 2 1451.700523 726.8569 Filamin-A OS=Homo sapiens OX=9606 GN=FLNA PE=1 SV=4 5.88 1585.9 - 39588.5 - - - 0.8845 - 1.325 0.555 - 41.5 1 2 0 0.0013 17 0 0 0 1.69E+06 1.38E+06 - - - 3.8317 0.9992 221125_WJC_METTL3_EV_vs_WT_F07.06228.06228.2 0.637 16-Aug K.DSSGWSSSK[136.11].D "sp|O00571|DDX3X_HUMAN,tr|A0A2R8YFR4|A0A2R8YFR4_HUMAN,tr|A0A2R8YCW1|A0A2R8YCW1_HUMAN,tr|A0A2R8YDH3|A0A2R8YDH3_HUMAN,tr|A0A2R8Y645|A0A2R8Y645_HUMAN,tr|A0A2R8YF78|A0A2R8YF78_HUMAN,tr|A0A2R8YCU0|A0A2R8YCU0_HUMAN,tr|A0A0D9SFB3|A0A0D9SFB3_HUMAN,tr|A0A2R8YFS5|A0A2R8YFS5_HUMAN,tr|A0A0D9SF53|A0A0D9SF53_HUMAN,tr|A0A2R8Y650|A0A2R8Y650_HUMAN,tr|A0A087WX09|A0A087WX09_HUMAN,tr|A0A2R8Y5G6|A0A2R8Y5G6_HUMAN,tr|A0A0D9SG12|A0A0D9SG12_HUMAN,tr|F6S8Q4|F6S8Q4_HUMAN,tr|A0A2U3TZJ9|A0A2U3TZJ9_HUMAN,tr|A0A2R8Y4A4|A0A2R8Y4A4_HUMAN,tr|A0A2R8YF89|A0A2R8YF89_HUMAN" 18 947.4076 1.12 95031 6228 2 947.408947 474.7111 ATP-dependent RNA helicase DDX3X OS=Homo sapiens OX=9606 GN=DDX3X PE=1 SV=3 5.84 1586.5 - 2.15E+06 - - - 1.4323 - 1.697 0.331 - 303.6 1 2 0 0.0014 9 0 0 0 2.07E+08 1.85E+08 - - - 3.0154 0.8492 221125_WJC_METTL3_EV_vs_WT_F07.06229.06229.2 0.039 20-Jun F.GQSGAGNNWAK[136.11].G "sp|P04350|TBB4A_HUMAN,sp|Q9BVA1|TBB2B_HUMAN,sp|P07437|TBB5_HUMAN,sp|Q13509|TBB3_HUMAN,sp|Q13885|TBB2A_HUMAN,sp|P68371|TBB4B_HUMAN,tr|A0A0B4J269|A0A0B4J269_HUMAN,tr|Q5ST81|Q5ST81_HUMAN,tr|Q5JP53|Q5JP53_HUMAN,tr|M0QY85|M0QY85_HUMAN,tr|M0QZL7|M0QZL7_HUMAN,tr|G3V542|G3V542_HUMAN,tr|G3V2A3|G3V2A3_HUMAN,tr|M0R278|M0R278_HUMAN,tr|M0R1I1|M0R1I1_HUMAN" 15 1096.5141 0.73 95032 6229 2 1096.516464 549.2643 Tubulin beta-4A chain OS=Homo sapiens OX=9606 GN=TUBB4A PE=1 SV=2 8.75 1586.6 - 234735 - - - 2.1377 - 1.391 0.312 - 123.7 1 1 0 0.0023 11 0 0 0 8.78E+07 1.20E+08 - - - 2.2375 0.9997 221125_WJC_METTL3_EV_vs_WT_F07.06245.06245.2 0.000508 22-Jul K.LSNSDSQDIQGR.N sp|O14545|TRAD1_HUMAN 1 1318.6113 0.41 95043 6245 2 1318.611733 660.3129 TRAF-type zinc finger domain-containing protein 1 OS=Homo sapiens OX=9606 GN=TRAFD1 PE=1 SV=1 4.21 1588.7 - 53467.6 - - - 0.3117 - 1.583 0.456 - 129.7 1 2 0 0.0004 12 0 0 0 6.27E+06 1.53E+07 - - - 3.6174 0.9991 221125_WJC_METTL3_EV_vs_WT_F07.06248.06248.3 0.018 Aug-36 R.YNGEPEHIER[166.11].N "sp|Q14739|LBR_HUMAN,tr|A0A494C1L1|A0A494C1L1_HUMAN,tr|C9JXK0|C9JXK0_HUMAN" 3 1252.5712 0.77 95045 6248 3 1252.571088 418.531 Delta(14)-sterol reductase LBR OS=Homo sapiens OX=9606 GN=LBR PE=1 SV=2 4.75 1589 - 413344 - - - -0.0774 - 1.442 0.34 - 77.8 1 2 0 -0.0001 10 0 0 0 2.58E+07 3.36E+07 - - - 3.3996 0.9998 221125_WJC_METTL3_EV_vs_WT_F07.06249.06249.2 1.08E-05 15/18 K.HESQMDSVVK[136.11].D "sp|Q00765|REEP5_HUMAN,tr|E2QRG8|E2QRG8_HUMAN" 2 1166.5481 0.99 95046 6249 2 1166.550208 584.2813 Receptor expression-enhancing protein 5 OS=Homo sapiens OX=9606 GN=REEP5 PE=1 SV=3 5.32 1589.1 - 713194 - - - 1.7873 - 2.918 0.495 - 722 1 2 0 0.0021 10 0 0 0 4.46E+07 4.53E+07 - - - 5.6856 1 221125_WJC_METTL3_EV_vs_WT_F07.06250.06250.3 0.000401 14/36 R.EGTETFADHR[166.11].E sp|Q9Y490|TLN1_HUMAN 1 1171.5133 1.24 95047 6250 3 1171.513425 391.5117 Talin-1 OS=Homo sapiens OX=9606 GN=TLN1 PE=1 SV=3 4.65 1589.3 - 427500 - - - 0.0768 - 2.197 0.499 - 371.3 1 2 0 0.0001 10 0 0 0 2.50E+07 2.01E+07 - - - 6.402 0.9643 221125_WJC_METTL3_EV_vs_WT_F07.06257.06257.2 0.00348 20-Oct F.GQSGAGNNWAK.G "sp|P04350|TBB4A_HUMAN,sp|Q9BVA1|TBB2B_HUMAN,sp|P07437|TBB5_HUMAN,sp|Q13509|TBB3_HUMAN,sp|Q13885|TBB2A_HUMAN,sp|P68371|TBB4B_HUMAN,tr|A0A0B4J269|A0A0B4J269_HUMAN,tr|Q5ST81|Q5ST81_HUMAN,tr|Q5JP53|Q5JP53_HUMAN,tr|M0QY85|M0QY85_HUMAN,tr|M0QZL7|M0QZL7_HUMAN,tr|G3V542|G3V542_HUMAN,tr|G3V2A3|G3V2A3_HUMAN,tr|M0R278|M0R278_HUMAN,tr|M0R1I1|M0R1I1_HUMAN" 15 1088.4999 0.73 95051 6257 2 1088.500538 545.2572 Tubulin beta-4A chain OS=Homo sapiens OX=9606 GN=TUBB4A PE=1 SV=2 8.75 1590.2 - 779822 - - - 0.5678 - 1.821 0.306 - 428.6 1 1 0 0.0006 11 0 0 0 8.78E+07 1.21E+08 - - - 2.9224 0.9996 221125_WJC_METTL3_EV_vs_WT_F07.06259.06259.2 0.0115 20-Sep K.DSSQLGTDATK.E "sp|O43491|E41L2_HUMAN,tr|E9PIG0|E9PIG0_HUMAN,tr|A0A2R8Y5B3|A0A2R8Y5B3_HUMAN,tr|E9PII3|E9PII3_HUMAN,tr|E9PHY5|E9PHY5_HUMAN,tr|E9PK52|E9PK52_HUMAN,tr|E9PRG1|E9PRG1_HUMAN,tr|E9PJP4|E9PJP4_HUMAN,tr|E9PQD2|E9PQD2_HUMAN,tr|E9PQN0|E9PQN0_HUMAN" 10 1121.52 0.99 95053 6259 2 1121.521031 561.7673 Band 4.1-like protein 2 OS=Homo sapiens OX=9606 GN=EPB41L2 PE=1 SV=1 4.21 1590.4 - 522159 - - - 0.8774 - 1.753 0.411 - 328 1 2 0 0.001 11 0 0 0 4.20E+07 4.26E+07 - - - 3.5949 0.9652 221125_WJC_METTL3_EV_vs_WT_F07.06260.06260.2 0.00977 20-Sep K.SSATIQNETPK.K "sp|Q5HYJ3|FA76B_HUMAN,tr|F5GX09|F5GX09_HUMAN" 2 1174.583 1.01 95054 6260 2 1174.575438 588.2988 Protein FAM76B OS=Homo sapiens OX=9606 GN=FAM76B PE=1 SV=3 5.72 1590.6 - 206245 - - - -6.4219 - 1.565 0.332 - 238.8 1 2 0 -0.0075 11 0 0 0 1.85E+07 1.84E+07 - - - 2.7024 1 221125_WJC_METTL3_EV_vs_WT_F07.06264.06264.3 0.000223 Dec-40 R.TLHGQETYTPR.L "sp|Q9BUK6|MSTO1_HUMAN,tr|A0A3B3IUD2|A0A3B3IUD2_HUMAN" 2 1301.6364 1.84 95057 6264 3 1301.636183 434.8861 Protein misato homolog 1 OS=Homo sapiens OX=9606 GN=MSTO1 PE=1 SV=1 6.41 1591 - 1.16E+06 - - - -0.1775 - 2.323 0.485 - 309.1 1 2 0 -0.0002 11 0 0 0 3.76E+07 2.05E+07 - - - 6.3416 0.9927 221125_WJC_METTL3_EV_vs_WT_F07.06266.06266.2 0.00299 14-Aug K.EVSTYIK[136.11]K[136.11].L "sp|P68104|EF1A1_HUMAN,sp|Q5VTE0|EF1A3_HUMAN,tr|A0A7I2V659|A0A7I2V659_HUMAN,tr|A0A7I2V3H3|A0A7I2V3H3_HUMAN,tr|A0A7I2V5N4|A0A7I2V5N4_HUMAN,tr|A0A087WVQ9|A0A087WVQ9_HUMAN,tr|A0A087WV01|A0A087WV01_HUMAN" 7 982.567 0.04 95059 6266 2 982.567652 492.2908 Elongation factor 1-alpha 1 OS=Homo sapiens OX=9606 GN=EEF1A1 PE=1 SV=1 8.59 1591.2 - 362676 - - - 0.6666 - 1.32 0.143 - 298.7 1 2 0 0.0007 8 0 0 0 8.91E+05 2.40E+07 - - - 0.9343 0.9994 221125_WJC_METTL3_EV_vs_WT_F07.06272.06272.2 0.0202 28-Aug M.PGPTPSGTNVGSSGR[166.11].S sp|P60468|SC61B_HUMAN 1 1379.6669 0.84 95062 6272 2 1379.666657 690.8407 Protein transport protein Sec61 subunit beta OS=Homo sapiens OX=9606 GN=SEC61B PE=1 SV=2 10.18 1591.9 - 92338.4 - - - -0.1587 - 1.487 0.379 - 126.4 1 2 0 -0.0002 15 0 0 0 7.14E+07 8.48E+07 - - - 2.8157 0.9558 221125_WJC_METTL3_EV_vs_WT_F07.06273.06273.2 0.0228 16-Aug K.HTDESLGDC[160.03].S "sp|Q86U44|MTA70_HUMAN,tr|H0YFV6|H0YFV6_HUMAN" 2 1032.3818 - 95063 6273 2 1032.383606 517.1982 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 4.02 1592 - 1.10E+06 - - - 1.7116 - 1.341 0.457 - 142.6 1 1 0 0.0018 9 0 0 0 - - - - - 3.2647 0.8801 221125_WJC_METTL3_EV_vs_WT_F07.06278.06278.2 5.92 18-Apr K.SC[160.03]EQAC[160.03]ESLK[136.11].R "sp|P42694|HELZ_HUMAN,tr|J3KT20|J3KT20_HUMAN,tr|J3QS41|J3QS41_HUMAN,tr|A0A075B6R3|A0A075B6R3_HUMAN,tr|J3KS59|J3KS59_HUMAN" 5 1218.51 2.59 95065 6278 2 1218.513342 610.2623 Probable helicase with zinc finger domain OS=Homo sapiens OX=9606 GN=HELZ PE=1 SV=2 4.53 1592.8 - 96121.5 - - - 2.7238 - 1.06 0.099 - 34.4 2 2 0 0.0033 10 0 0 0 1.65E+07 6.39E+06 - - - -0.2007 0.9994 221125_WJC_METTL3_EV_vs_WT_F07.06289.06289.3 0.00133 Dec-36 R.EGTETFADHR.E sp|Q9Y490|TLN1_HUMAN 1 1161.5051 1.24 95073 6289 3 1161.50507 388.1756 Talin-1 OS=Homo sapiens OX=9606 GN=TLN1 PE=1 SV=3 4.65 1594.1 - 492700 - - - 0.0043 - 1.737 0.32 - 247.6 1 2 0 0 10 0 0 0 2.50E+07 2.01E+07 - - - 3.7202 0.9885 221125_WJC_METTL3_EV_vs_WT_F07.06300.06300.2 0.266 16-Apr R.ASYDDPYK[136.11]K[136.11].A sp|Q96PK6|RBM14_HUMAN 1 1101.5313 1.94 95078 6300 2 1101.532016 551.7729 RNA-binding protein 14 OS=Homo sapiens OX=9606 GN=RBM14 PE=1 SV=2 6 1595.6 - 215731 - - - 0.6137 - 0.972 0.274 - 41.6 7 2 0 0.0007 9 0 0 0 1.05E+09 5.40E+08 - - - 0.6049 0.9874 221125_WJC_METTL3_EV_vs_WT_F07.06307.06307.2 0.00408 18-Jul R.SHEGETSYIR.V sp|Q13242|SRSF9_HUMAN 1 1177.5364 1.04 95081 6307 2 1177.542884 589.7755 Serine\arginine-rich splicing factor 9 OS=Homo sapiens OX=9606 GN=SRSF9 PE=1 SV=1 5.38 1596.5 - 414255 - - - 5.5353 - 1.212 0.483 - 173.9 1 2 0 0.0065 10 0 0 0 5.92E+07 5.69E+07 - - - 3.1431 0.9974 221125_WJC_METTL3_EV_vs_WT_F07.06314.06314.2 0.262 16-Jun K.SFTASVDRK.F "sp|Q9H8H0|NOL11_HUMAN,tr|J3QR28|J3QR28_HUMAN" 2 1009.5193 1.18 95085 6314 2 1009.518595 505.7669 Nucleolar protein 11 OS=Homo sapiens OX=9606 GN=NOL11 PE=1 SV=1 8.46 1597.3 - 193354 - - - -0.6577 - 1.346 0.234 - 121.4 1 2 0 -0.0007 9 0 0 0 7.12E+06 6.04E+06 - - - 1.6287 0.9925 221125_WJC_METTL3_EV_vs_WT_F07.06325.06325.2 0.016 14-May R.KYDEDLGR.V sp|Q86XZ4|SPAS2_HUMAN 1 994.472 1.81 95088 6325 2 994.467409 498.2433 Spermatogenesis-associated serine-rich protein 2 OS=Homo sapiens OX=9606 GN=SPATS2 PE=1 SV=1 4.56 1598.9 - 142791 - - - -4.5904 - 1.455 0.38 - 82.1 1 2 0 -0.0046 8 0 0 0 1.36E+07 7.52E+06 - - - 2.9772 0.9998 221125_WJC_METTL3_EV_vs_WT_F07.06332.06332.2 0.000251 20-Aug R.GHLENNPALEK.L "sp|Q8NHW5|RLA0L_HUMAN,sp|P05388|RLA0_HUMAN,tr|G3V210|G3V210_HUMAN,tr|F8VU65|F8VU65_HUMAN,tr|F8VWV4|F8VWV4_HUMAN,tr|F8VWS0|F8VWS0_HUMAN,tr|F8VS58|F8VS58_HUMAN,tr|F8VW21|F8VW21_HUMAN,tr|F8VZS0|F8VZS0_HUMAN,tr|F8VRK7|F8VRK7_HUMAN,tr|F8VQY6|F8VQY6_HUMAN,tr|F8VPE8|F8VPE8_HUMAN" 12 1220.6149 1.15 95091 6332 2 1220.615004 611.3148 60S acidic ribosomal protein P0-like OS=Homo sapiens OX=9606 GN=RPLP0P6 PE=5 SV=1 5.4 1599.8 - 193776 - - - 0.0442 - 1.807 0.477 - 166.2 1 2 0 0.0001 11 0 0 0 7.89E+07 6.89E+07 - - - 4.1647 0.9998 221125_WJC_METTL3_EV_vs_WT_F07.06334.06334.2 0.000267 20-Sep K.ISTTTSEEPC[160.03]R.D sp|O15119|TBX3_HUMAN 1 1279.5714 0.65 95092 6334 2 1279.572369 640.793 T-box transcription factor TBX3 OS=Homo sapiens OX=9606 GN=TBX3 PE=1 SV=4 4.53 1600.1 - 386595 - - - 0.7331 - 1.934 0.498 - 303.4 1 2 0 0.0009 11 0 0 0 2.14E+07 3.26E+07 - - - 4.5033 0.9996 221125_WJC_METTL3_EV_vs_WT_F07.06344.06344.2 0.000184 18-Aug R.SHEGETSYIR[166.11].V sp|Q13242|SRSF9_HUMAN 1 1187.5446 1.04 95099 6344 2 1187.54499 594.7796 Serine\arginine-rich splicing factor 9 OS=Homo sapiens OX=9606 GN=SRSF9 PE=1 SV=1 5.38 1601.3 - 759408 - - - 0.2981 - 1.591 0.409 - 191.3 1 2 0 0.0004 10 0 0 0 5.92E+07 5.69E+07 - - - 3.3579 0.9879 221125_WJC_METTL3_EV_vs_WT_F07.06345.06345.2 0.00185 14/28 M.PGPTPSGTNVGSSGR.S sp|P60468|SC61B_HUMAN 1 1369.6586 0.85 95100 6345 2 1369.648241 685.8366 Protein transport protein Sec61 subunit beta OS=Homo sapiens OX=9606 GN=SEC61B PE=1 SV=2 10.18 1601.4 - 990065 - - - -7.5676 - 2.454 0.5 - 398.7 1 2 0 -0.0104 15 0 0 0 7.14E+07 8.44E+07 - - - 4.9378 0.9917 221125_WJC_METTL3_EV_vs_WT_F07.06346.06346.2 0.00294 22-Aug K.ADK[136.11]NEVAAEVAK[136.11].L "sp|P56192|SYMC_HUMAN,tr|H0YIP0|H0YIP0_HUMAN" 2 1259.6692 0.79 95101 6346 2 1259.669998 630.8419 "Methionine--tRNA ligase, cytoplasmic OS=Homo sapiens OX=9606 GN=MARS1 PE=1 SV=2" 4.68 1601.5 - 259200 - - - 0.6089 - 1.398 0.383 - 157.7 1 2 1 0.0008 12 0 0 0 1.41E+07 1.78E+07 - - - 2.7512 0.9993 221125_WJC_METTL3_EV_vs_WT_F07.06352.06352.2 0.00788 22-Jul K.VPQAQPTKPALK.S "sp|O95793|STAU1_HUMAN,tr|Q5JW30|Q5JW30_HUMAN" 2 1276.7503 2.32 95105 6352 2 1276.750245 639.3824 Double-stranded RNA-binding protein Staufen homolog 1 OS=Homo sapiens OX=9606 GN=STAU1 PE=1 SV=2 10 1602.2 - 359916 - - - -0.0603 - 1.556 0.344 - 99.9 1 2 0 -0.0001 12 0 0 0 6.90E+07 2.98E+07 - - - 2.745 0.8835 221125_WJC_METTL3_EV_vs_WT_F07.06353.06353.3 1.54 Sep-52 R.GVPGTEPEK[136.11]DPGPR[166.11].A "sp|Q6QNY0|BL1S3_HUMAN,tr|K7EN58|K7EN58_HUMAN" 2 1452.7328 2 95106 6353 3 1452.733319 485.2515 Biogenesis of lysosome-related organelles complex 1 subunit 3 OS=Homo sapiens OX=9606 GN=BLOC1S3 PE=1 SV=1 4.68 1602.4 - 258770 - - - 0.3731 - 1.636 0.121 - 60.3 1 2 1 0.0005 14 0 0 0 6.98E+07 3.49E+07 - - - 1.1971 0.9899 221125_WJC_METTL3_EV_vs_WT_F07.06356.06356.2 0.000893 14-Sep A.SYDDPYKK.A sp|Q96PK6|RBM14_HUMAN 1 1014.4658 1.26 95107 6356 2 1014.465921 508.2402 RNA-binding protein 14 OS=Homo sapiens OX=9606 GN=RBM14 PE=1 SV=2 5.68 1602.8 - 838244 - - - 0.0936 - 1.562 0.533 - 234.7 1 1 0 0.0001 8 0 0 0 3.65E+08 2.90E+08 - - - 4.3227 0.9898 221125_WJC_METTL3_EV_vs_WT_F07.06358.06358.3 0.0215 Dec-44 K.ADK[136.11]NEVAAEVAK[136.11].L "sp|P56192|SYMC_HUMAN,tr|H0YIP0|H0YIP0_HUMAN" 2 1259.6692 1.27 95108 6358 3 1259.669467 420.897 "Methionine--tRNA ligase, cytoplasmic OS=Homo sapiens OX=9606 GN=MARS1 PE=1 SV=2" 4.68 1603 - 1.22E+06 - - - 0.1874 - 1.851 0.225 - 119.9 1 2 1 0.0002 12 0 0 0 1.01E+08 7.98E+07 - - - 2.7552 0.9999 221125_WJC_METTL3_EV_vs_WT_F07.06360.06360.2 2.73E-06 16-Sep R.ASYDDPYKK.A sp|Q96PK6|RBM14_HUMAN 1 1085.5029 1.94 95109 6360 2 1085.503902 543.7587 RNA-binding protein 14 OS=Homo sapiens OX=9606 GN=RBM14 PE=1 SV=2 6 1603.2 - 2.64E+06 - - - 0.8862 - 1.808 0.604 - 302 1 2 0 0.001 9 0 0 0 1.05E+09 5.40E+08 - - - 5.2152 0.8773 221125_WJC_METTL3_EV_vs_WT_F07.06367.06367.3 0.381 Jun-40 R.LK[136.11]TEGSDLC[160.03]DR[166.11].V "sp|P04843|RPN1_HUMAN,tr|B7Z4L4|B7Z4L4_HUMAN" 2 1310.6255 1.05 95114 6367 3 1310.627493 437.8825 Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit 1 OS=Homo sapiens OX=9606 GN=RPN1 PE=1 SV=1 4.56 1604.1 - 362199 - - - 1.4939 - 1.468 0.156 - 65 1 2 1 0.002 11 0 0 0 7.25E+07 6.92E+07 - - - 1.3693 0.9994 221125_WJC_METTL3_EV_vs_WT_F07.06378.06378.2 0.00411 18-Aug K.QQLHNSNIIK.K "sp|P82094|TMF1_HUMAN,tr|F8WF45|F8WF45_HUMAN,tr|A0A2R8Y7M0|A0A2R8Y7M0_HUMAN" 3 1193.6517 1.66 95123 6378 2 1193.651902 597.8331 TATA element modulatory factor OS=Homo sapiens OX=9606 GN=TMF1 PE=1 SV=2 8.76 1605.4 - 615156 - - - 0.1944 - 1.651 0.336 - 179.2 1 2 0 0.0002 10 0 0 0 2.79E+07 1.68E+07 - - - 2.9221 0.9997 221125_WJC_METTL3_EV_vs_WT_F07.06381.06381.2 0.00495 18-Oct K.QQLHNSNIIK[136.11].K "sp|P82094|TMF1_HUMAN,tr|F8WF45|F8WF45_HUMAN,tr|A0A2R8Y7M0|A0A2R8Y7M0_HUMAN" 3 1201.6659 1.85 95126 6381 2 1201.665484 601.8402 TATA element modulatory factor OS=Homo sapiens OX=9606 GN=TMF1 PE=1 SV=2 8.76 1605.8 - 302949 - - - -0.3212 - 1.828 0.385 - 299 1 2 0 -0.0004 10 0 0 0 1.42E+07 7.70E+06 - - - 3.5683 0.9999 221125_WJC_METTL3_EV_vs_WT_F07.06386.06386.3 1.13E-06 14/44 K.VPQAQPTKPALK.S "sp|O95793|STAU1_HUMAN,tr|Q5JW30|Q5JW30_HUMAN" 2 1276.7503 2.15 95128 6386 3 1276.750982 426.5907 Double-stranded RNA-binding protein Staufen homolog 1 OS=Homo sapiens OX=9606 GN=STAU1 PE=1 SV=2 10 1606.6 - 9.82E+06 - - - 0.5169 - 2.122 0.399 - 274.5 1 2 0 0.0007 12 0 0 0 9.76E+08 4.53E+08 - - - 5.0737 0.9925 221125_WJC_METTL3_EV_vs_WT_F07.06393.06393.2 4.66E-06 14-Oct A.SYDDPYK[136.11]K[136.11].A sp|Q96PK6|RBM14_HUMAN 1 1030.4942 1.94 95133 6393 2 1030.49444 516.2544 RNA-binding protein 14 OS=Homo sapiens OX=9606 GN=RBM14 PE=1 SV=2 5.68 1607.5 - 1.99E+06 - - - 0.2077 - 1.743 0.556 - 286.3 1 1 0 0.0002 8 0 0 0 3.50E+08 1.80E+08 - - - 4.8232 0.9986 221125_WJC_METTL3_EV_vs_WT_F07.06395.06395.2 4.09E-07 20-Sep R.LK[136.11]TEGSDLC[160.03]DR[166.11].V "sp|P04843|RPN1_HUMAN,tr|B7Z4L4|B7Z4L4_HUMAN" 2 1310.6255 1.56 95135 6395 2 1310.624039 656.32 Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit 1 OS=Homo sapiens OX=9606 GN=RPN1 PE=1 SV=1 4.56 1607.7 - 241996 - - - -1.1414 - 2.08 0.571 - 169.6 1 2 1 -0.0015 11 0 0 0 1.62E+07 1.04E+07 - - - 5.2392 0.9997 221125_WJC_METTL3_EV_vs_WT_F07.06396.06396.2 0.00171 18-Aug R.TDSPDMHEDT.- sp|Q9BW61|DDA1_HUMAN 1 1146.4135 - 95136 6396 2 1146.41348 574.214 DET1- and DDB1-associated protein 1 OS=Homo sapiens OX=9606 GN=DDA1 PE=1 SV=1 3.84 1607.9 - 222125 - - - -0.0462 - 1.487 0.442 - 180.5 1 2 0 -0.0001 10 0 0 0 - - - - - 3.4131 0.9998 221125_WJC_METTL3_EV_vs_WT_F07.06402.06402.2 0.000357 24-Sep K.QLQSEQPQTAAAR.S "sp|Q9UI12|VATH_HUMAN,tr|G3V126|G3V126_HUMAN" 2 1426.7165 1.27 95139 6402 2 1426.715795 714.3655 V-type proton ATPase subunit H OS=Homo sapiens OX=9606 GN=ATP6V1H PE=1 SV=1 6 1608.7 - 175471 - - - -0.4626 - 1.927 0.487 - 195 1 2 0 -0.0007 13 0 0 0 1.10E+07 8.65E+06 - - - 4.3213 0.9995 221125_WJC_METTL3_EV_vs_WT_F07.06410.06410.2 0.000444 22-Sep R.GGPAGPYQQSQR[166.11].L "sp|Q5JPH6|SYEM_HUMAN,tr|H3BTB7|H3BTB7_HUMAN" 2 1254.5981 1.42 95143 6410 2 1254.601632 628.3063 "Probable glutamate--tRNA ligase, mitochondrial OS=Homo sapiens OX=9606 GN=EARS2 PE=1 SV=2" 8.75 1609.7 - 180712 - - - 2.8408 - 2.071 0.504 - 301.6 1 2 0 0.0036 12 0 0 0 1.95E+07 1.38E+07 - - - 4.678 0.9998 221125_WJC_METTL3_EV_vs_WT_F07.06416.06416.2 0.000419 13/24 K.QLQSEQPQTAAAR[166.11].S "sp|Q9UI12|VATH_HUMAN,tr|G3V126|G3V126_HUMAN" 2 1436.7247 1.27 95147 6416 2 1436.724611 719.3696 V-type proton ATPase subunit H OS=Homo sapiens OX=9606 GN=ATP6V1H PE=1 SV=1 6 1610.5 - 176162 - - - -0.0793 - 2.471 0.397 - 539 1 2 0 -0.0001 13 0 0 0 1.10E+07 8.65E+06 - - - 4.2949 0.9989 221125_WJC_METTL3_EV_vs_WT_F07.06421.06421.2 0.0122 18-Jun K.VQYPQSQAC[160.03]K.M "sp|Q14204|DYHC1_HUMAN,tr|A0A7P0T8N2|A0A7P0T8N2_HUMAN,tr|A0A7P0T9C4|A0A7P0T9C4_HUMAN,tr|A0A7P0TBJ7|A0A7P0TBJ7_HUMAN,tr|A0A804HHY6|A0A804HHY6_HUMAN,tr|A0A7P0T9K2|A0A7P0T9K2_HUMAN,tr|A0A7P0TB64|A0A7P0TB64_HUMAN,tr|A0A2R8Y706|A0A2R8Y706_HUMAN,tr|A0A7P0T916|A0A7P0T916_HUMAN,tr|A0A7P0TB75|A0A7P0TB75_HUMAN,tr|A0A7P0T8W5|A0A7P0T8W5_HUMAN,tr|A0A7P0T9S3|A0A7P0T9S3_HUMAN,tr|A0A7P0TAF3|A0A7P0TAF3_HUMAN,tr|A0A7P0T9F1|A0A7P0T9F1_HUMAN,tr|A0A7P0TAW9|A0A7P0TAW9_HUMAN,tr|A0A2R8YGC7|A0A2R8YGC7_HUMAN,tr|A0A7P0TA13|A0A7P0TA13_HUMAN,tr|A0A7P0T934|A0A7P0T934_HUMAN,tr|A0A7P0TAV5|A0A7P0TAV5_HUMAN,tr|A0A7P0T9Y3|A0A7P0T9Y3_HUMAN,tr|A0A7P0T7V5|A0A7P0T7V5_HUMAN,tr|A0A7P0T9R4|A0A7P0T9R4_HUMAN,tr|A0A2R8Y5T0|A0A2R8Y5T0_HUMAN,tr|A0A7P0T990|A0A7P0T990_HUMAN,tr|A0A7P0T942|A0A7P0T942_HUMAN,tr|A0A2R8YFZ7|A0A2R8YFZ7_HUMAN,tr|A0A7P0T825|A0A7P0T825_HUMAN,tr|A0A2R8Y6H2|A0A2R8Y6H2_HUMAN,tr|A0A7P0TBC9|A0A7P0TBC9_HUMAN,tr|A0A7P0TAM4|A0A7P0TAM4_HUMAN" 30 1207.5656 0.66 95150 6421 2 1207.564666 604.7901 Cytoplasmic dynein 1 heavy chain 1 OS=Homo sapiens OX=9606 GN=DYNC1H1 PE=1 SV=5 8.17 1611.1 - 210800 - - - -0.7387 - 1.307 0.353 - 132.2 1 2 0 -0.0009 10 0 0 0 2.02E+07 3.08E+07 - - - 2.3953 0.9991 221125_WJC_METTL3_EV_vs_WT_F07.06426.06426.3 0.000113 Dec-32 R.WDETPKTER.D sp|O75533|SF3B1_HUMAN 1 1160.5462 0.61 95153 6426 3 1160.547344 387.856 Splicing factor 3B subunit 1 OS=Homo sapiens OX=9606 GN=SF3B1 PE=1 SV=3 4.68 1611.8 - 1.17E+06 - - - 0.984 - 2.006 0.361 - 240 1 2 1 0.0011 9 0 0 0 4.39E+07 7.15E+07 - - - 4.6625 0.9956 221125_WJC_METTL3_EV_vs_WT_F07.06427.06427.2 0.00387 20-Aug R.LKTEGSDLC[160.03]DR.V "sp|P04843|RPN1_HUMAN,tr|B7Z4L4|B7Z4L4_HUMAN" 2 1292.6031 1.43 95154 6427 2 1292.603821 647.3088 Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit 1 OS=Homo sapiens OX=9606 GN=RPN1 PE=1 SV=1 4.56 1611.9 - 364927 - - - 0.5849 - 1.49 0.442 - 125.7 1 2 1 0.0008 11 0 0 0 1.64E+07 1.14E+07 - - - 3.3842 0.9713 221125_WJC_METTL3_EV_vs_WT_F07.06430.06430.2 0.000317 20-Sep V.PQAQPTKPALK.S "sp|O95793|STAU1_HUMAN,tr|Q5JW30|Q5JW30_HUMAN" 2 1177.6819 3.13 95157 6430 2 1177.682431 589.8482 Double-stranded RNA-binding protein Staufen homolog 1 OS=Homo sapiens OX=9606 GN=STAU1 PE=1 SV=2 10.02 1612.2 - 310931 - - - 0.4441 - 1.484 0.407 - 277 1 1 0 0.0005 11 0 0 0 2.41E+07 7.71E+06 - - - 3.1148 0.9655 221125_WJC_METTL3_EV_vs_WT_F07.06443.06443.2 0.000102 12-Sep S.YDDPYK[136.11]K[136.11].A sp|Q96PK6|RBM14_HUMAN 1 943.4622 1.93 95163 6443 2 943.461626 472.7384 RNA-binding protein 14 OS=Homo sapiens OX=9606 GN=RBM14 PE=1 SV=2 5.96 1613.9 - 2.68E+06 - - - -0.6063 - 1.675 0.301 - 237.7 1 1 0 -0.0006 7 0 0 0 2.16E+08 1.11E+08 - - - 2.8984 0.9977 221125_WJC_METTL3_EV_vs_WT_F07.06452.06452.2 0.0132 24-Jul K.ASSTSLTSTQPTK[136.11].T "sp|P35658|NU214_HUMAN,tr|A0A0A0MSW3|A0A0A0MSW3_HUMAN,tr|E9PKD2|E9PKD2_HUMAN,tr|B7ZAV2|B7ZAV2_HUMAN,tr|A0A494C1F2|A0A494C1F2_HUMAN,tr|H0Y837|H0Y837_HUMAN" 6 1315.6711 2.31 95168 6452 2 1315.675109 658.8428 Nuclear pore complex protein Nup214 OS=Homo sapiens OX=9606 GN=NUP214 PE=1 SV=2 8.8 1615.1 - 111086 - - - 3.0661 - 1.534 0.396 - 142.8 1 2 0 0.004 13 0 0 0 8.03E+06 3.47E+06 - - - 3.0628 0.9999 221125_WJC_METTL3_EV_vs_WT_F07.06458.06458.2 1.39E-07 20-Nov R.QTTQDAPEEVR.N sp|Q9P013|CWC15_HUMAN 1 1272.5946 0.77 95170 6458 2 1272.595491 637.3046 Spliceosome-associated protein CWC15 homolog OS=Homo sapiens OX=9606 GN=CWC15 PE=1 SV=2 4.14 1615.9 - 756837 - - - 0.6931 - 2.476 0.515 - 576.6 1 2 0 0.0009 11 0 0 0 4.47E+07 5.81E+07 - - - 5.2972 0.9998 221125_WJC_METTL3_EV_vs_WT_F07.06459.06459.2 1.17E-06 24-Sep K.ASSTSLTSTQPTK.T "sp|P35658|NU214_HUMAN,tr|A0A0A0MSW3|A0A0A0MSW3_HUMAN,tr|E9PKD2|E9PKD2_HUMAN,tr|B7ZAV2|B7ZAV2_HUMAN,tr|A0A494C1F2|A0A494C1F2_HUMAN,tr|H0Y837|H0Y837_HUMAN" 6 1307.6569 2.31 95171 6459 2 1307.65849 654.8357 Nuclear pore complex protein Nup214 OS=Homo sapiens OX=9606 GN=NUP214 PE=1 SV=2 8.8 1616 - 355895 - - - 1.235 - 2.402 0.462 - 295.1 1 2 0 0.0016 13 0 0 0 8.03E+06 3.47E+06 - - - 4.7019 1 221125_WJC_METTL3_EV_vs_WT_F07.06469.06469.3 1.42E-05 13/44 K.VPQAQPTK[136.11]PALK[136.11].S "sp|O95793|STAU1_HUMAN,tr|Q5JW30|Q5JW30_HUMAN" 2 1292.7787 2.16 95175 6469 3 1292.778733 431.9335 Double-stranded RNA-binding protein Staufen homolog 1 OS=Homo sapiens OX=9606 GN=STAU1 PE=1 SV=2 10 1617.3 - 6.64E+06 - - - 0.0085 - 2.189 0.526 - 248.9 1 2 0 0 12 0 0 0 9.61E+08 4.45E+08 - - - 6.576 0.9999 221125_WJC_METTL3_EV_vs_WT_F07.06471.06471.2 1.77E-06 24-Dec R.FSSSSGYGGGSSR.V sp|P35527|K1C9_HUMAN 1 1234.5214 19587.88 95176 6471 2 1234.521658 618.268 "Keratin, type I cytoskeletal 9 OS=Homo sapiens OX=9606 GN=KRT9 PE=1 SV=3" 8.75 1617.5 - 1.02E+07 - - - 0.1733 - 2.323 0.583 - 397 1 2 0 0.0002 13 0 0 0 7.92E+09 4.04E+05 - - - 5.5102 0.9986 221125_WJC_METTL3_EV_vs_WT_F07.06475.06475.3 0.206 Nov-44 R.EQVVEDR[166.11]PVGGR[166.11].G sp|Q8NBJ4|GOLM1_HUMAN 1 1359.701 1.22 95178 6475 3 1359.699966 454.2409 Golgi membrane protein 1 OS=Homo sapiens OX=9606 GN=GOLM1 PE=1 SV=1 4.68 1618.1 - 2.01E+06 - - - -0.7362 - 1.533 0.3 - 199.1 1 2 0 -0.001 12 0 0 0 1.08E+08 8.83E+07 - - - 3.0686 0.9997 221125_WJC_METTL3_EV_vs_WT_F07.06476.06476.2 0.0227 16-Dec K.R[166.11]GEAPFAQR[166.11].L "sp|Q9Y2R0|COA3_HUMAN,tr|K7EPV0|K7EPV0_HUMAN" 2 1050.5474 1.37 95179 6476 2 1050.546406 526.281 "Cytochrome c oxidase assembly factor 3 homolog, mitochondrial OS=Homo sapiens OX=9606 GN=COA3 PE=1 SV=1" 9.6 1618.2 - 1.50E+06 - - - -0.9148 - 2.212 0.312 - 278.6 1 2 0 -0.001 9 0 0 0 1.04E+08 7.56E+07 - - - 3.6419 0.9998 221125_WJC_METTL3_EV_vs_WT_F07.06484.06484.2 0.000736 18-Oct K.VQYPQSQAC[160.03]K[136.11].M "sp|Q14204|DYHC1_HUMAN,tr|A0A7P0T8N2|A0A7P0T8N2_HUMAN,tr|A0A7P0T9C4|A0A7P0T9C4_HUMAN,tr|A0A7P0TBJ7|A0A7P0TBJ7_HUMAN,tr|A0A804HHY6|A0A804HHY6_HUMAN,tr|A0A7P0T9K2|A0A7P0T9K2_HUMAN,tr|A0A7P0TB64|A0A7P0TB64_HUMAN,tr|A0A2R8Y706|A0A2R8Y706_HUMAN,tr|A0A7P0T916|A0A7P0T916_HUMAN,tr|A0A7P0TB75|A0A7P0TB75_HUMAN,tr|A0A7P0T8W5|A0A7P0T8W5_HUMAN,tr|A0A7P0T9S3|A0A7P0T9S3_HUMAN,tr|A0A7P0TAF3|A0A7P0TAF3_HUMAN,tr|A0A7P0T9F1|A0A7P0T9F1_HUMAN,tr|A0A7P0TAW9|A0A7P0TAW9_HUMAN,tr|A0A2R8YGC7|A0A2R8YGC7_HUMAN,tr|A0A7P0TA13|A0A7P0TA13_HUMAN,tr|A0A7P0T934|A0A7P0T934_HUMAN,tr|A0A7P0TAV5|A0A7P0TAV5_HUMAN,tr|A0A7P0T9Y3|A0A7P0T9Y3_HUMAN,tr|A0A7P0T7V5|A0A7P0T7V5_HUMAN,tr|A0A7P0T9R4|A0A7P0T9R4_HUMAN,tr|A0A2R8Y5T0|A0A2R8Y5T0_HUMAN,tr|A0A7P0T990|A0A7P0T990_HUMAN,tr|A0A7P0T942|A0A7P0T942_HUMAN,tr|A0A2R8YFZ7|A0A2R8YFZ7_HUMAN,tr|A0A7P0T825|A0A7P0T825_HUMAN,tr|A0A2R8Y6H2|A0A2R8Y6H2_HUMAN,tr|A0A7P0TBC9|A0A7P0TBC9_HUMAN,tr|A0A7P0TAM4|A0A7P0TAM4_HUMAN" 30 1215.5798 0.62 95185 6484 2 1215.579554 608.7972 Cytoplasmic dynein 1 heavy chain 1 OS=Homo sapiens OX=9606 GN=DYNC1H1 PE=1 SV=5 8.17 1619.2 - 871937 - - - -0.1678 - 1.701 0.517 - 377.4 1 2 0 -0.0002 10 0 0 0 1.92E+07 3.08E+07 - - - 4.3423 0.9977 221125_WJC_METTL3_EV_vs_WT_F07.06489.06489.3 0.0135 Sep-32 R.FAC[160.03]PVC[160.03]NK[136.11]R[166.11].F "sp|Q8IXZ3|SP8_HUMAN,sp|P0CG40|SP9_HUMAN,tr|A0A087X0Q6|A0A087X0Q6_HUMAN" 3 1168.56 1.45 95188 6489 3 1168.559801 390.5273 Transcription factor Sp8 OS=Homo sapiens OX=9606 GN=SP8 PE=1 SV=3 8.96 1619.8 - 1.10E+06 - - - -0.2037 - 1.615 0.247 - 98.9 1 2 0 -0.0002 9 0 0 0 6.12E+07 4.22E+07 - - - 2.7384 0.9998 221125_WJC_METTL3_EV_vs_WT_F07.06491.06491.2 0.00409 16-Oct K.RGEAPFAQR.L "sp|Q9Y2R0|COA3_HUMAN,tr|K7EPV0|K7EPV0_HUMAN" 2 1030.5308 1.38 95190 6491 2 1030.531182 516.2727 "Cytochrome c oxidase assembly factor 3 homolog, mitochondrial OS=Homo sapiens OX=9606 GN=COA3 PE=1 SV=1" 9.6 1620 - 2.00E+06 - - - 0.3445 - 1.918 0.41 - 164 1 2 0 0.0004 9 0 0 0 1.05E+08 7.61E+07 - - - 3.9533 0.9995 221125_WJC_METTL3_EV_vs_WT_F07.06492.06492.2 0.00019 13/22 R.DVIAQSQSGTGK.T "sp|P38919|IF4A3_HUMAN,tr|I3L3H2|I3L3H2_HUMAN" 2 1189.5939 1.56 95191 6492 2 1189.597518 595.8042 Eukaryotic initiation factor 4A-III OS=Homo sapiens OX=9606 GN=EIF4A3 PE=1 SV=4 5.84 1620.1 - 269708 - - - 3.0573 - 2.531 0.497 - 554.3 1 2 0 0.0036 12 0 0 0 2.93E+08 1.88E+08 - - - 5.154 0.9996 221125_WJC_METTL3_EV_vs_WT_F07.06495.06495.2 0.00549 16-Oct R.RQDSLESMK.F sp|P15924|DESP_HUMAN 1 1092.5234 497.42 95192 6495 2 1092.524482 547.269 Desmoplakin OS=Homo sapiens OX=9606 GN=DSP PE=1 SV=3 6.07 1620.5 - 1.08E+06 - - - 1.0288 - 2.101 0.309 - 484.2 1 2 0 0.0011 9 0 0 0 1.04E+08 2.09E+05 - - - 3.4708 0.9999 221125_WJC_METTL3_EV_vs_WT_F07.06497.06497.2 4.22E-06 18-Nov K.NQC[160.03]TQVVQER.E sp|P15924|DESP_HUMAN 1 1260.5881 12.42 95194 6497 2 1260.586706 631.3013 Desmoplakin OS=Homo sapiens OX=9606 GN=DSP PE=1 SV=3 5.99 1620.7 - 604821 - - - -1.0931 - 2.389 0.559 - 766.4 1 2 0 -0.0014 10 0 0 0 3.04E+08 2.45E+07 - - - 5.6002 0.9345 221125_WJC_METTL3_EV_vs_WT_F07.06498.06498.3 0.00811 Nov-44 L.QYADPVSAQHAK[136.11].L "sp|P26599|PTBP1_HUMAN,tr|A0A6Q8PEX4|A0A6Q8PEX4_HUMAN,tr|A0A0U1RRM4|A0A0U1RRM4_HUMAN,tr|A6NLN1|A6NLN1_HUMAN,tr|K7EKJ7|K7EKJ7_HUMAN,tr|A0A087WU68|A0A087WU68_HUMAN,tr|A0A7I2V4H6|A0A7I2V4H6_HUMAN,tr|A0A7I2V621|A0A7I2V621_HUMAN,tr|K7EK45|K7EK45_HUMAN" 9 1321.6506 1.9 95195 6498 3 1321.65007 441.5575 Polypyrimidine tract-binding protein 1 OS=Homo sapiens OX=9606 GN=PTBP1 PE=1 SV=1 6.74 1620.8 - 452422 - - - -0.4116 - 1.683 0.325 - 166.1 1 1 0 -0.0005 12 0 0 0 3.87E+07 2.04E+07 - - - 3.6062 0.9998 221125_WJC_METTL3_EV_vs_WT_F07.06499.06499.2 0.00186 22-Nov R.DVIAQSQSGTGK[136.11].T "sp|P38919|IF4A3_HUMAN,tr|I3L3H2|I3L3H2_HUMAN" 2 1197.6081 1.56 95196 6499 2 1197.609528 599.8113 Eukaryotic initiation factor 4A-III OS=Homo sapiens OX=9606 GN=EIF4A3 PE=1 SV=4 5.84 1620.9 - 396042 - - - 1.2082 - 2.204 0.469 - 370.1 1 2 0 0.0014 12 0 0 0 2.93E+08 1.88E+08 - - - 4.5839 0.9929 221125_WJC_METTL3_EV_vs_WT_F07.06500.06500.2 0.211 18-Jul K.ETEGDVTSVK.D sp|P50990|TCPQ_HUMAN 1 1063.5033 0.19 95197 6500 2 1063.506438 532.7589 T-complex protein 1 subunit theta OS=Homo sapiens OX=9606 GN=CCT8 PE=1 SV=4 4.14 1621.1 - 202870 - - - 2.9187 - 1.278 0.301 - 114.2 1 2 0 0.0031 10 0 0 0 4.60E+06 2.41E+07 - - - 1.9479 0.9999 221125_WJC_METTL3_EV_vs_WT_F07.06510.06510.3 0.000251 Nov-32 R.FAC[160.03]PVC[160.03]NKR.F "sp|Q8IXZ3|SP8_HUMAN,sp|P0CG40|SP9_HUMAN,tr|A0A087X0Q6|A0A087X0Q6_HUMAN" 3 1150.5376 1.43 95203 6510 3 1150.535629 384.5198 Transcription factor Sp8 OS=Homo sapiens OX=9606 GN=SP8 PE=1 SV=3 8.96 1622.2 - 1.28E+06 - - - -1.6862 - 1.947 0.432 - 150 1 2 0 -0.0019 9 0 0 0 6.16E+07 4.31E+07 - - - 5.3639 0.9347 221125_WJC_METTL3_EV_vs_WT_F07.06511.06511.3 0.00364 Aug-40 R.SFGTEDR[166.11]PTDR[166.11].P "sp|Q8ND56|LS14A_HUMAN,sp|Q9BX40|LS14B_HUMAN,tr|I3L4Q1|I3L4Q1_HUMAN,tr|Q5TBQ1|Q5TBQ1_HUMAN,tr|A0A140TA76|A0A140TA76_HUMAN,tr|K7EMZ9|K7EMZ9_HUMAN,tr|A0A0C4DFV2|A0A0C4DFV2_HUMAN,tr|Q5TBQ0|Q5TBQ0_HUMAN" 8 1299.5958 1.03 95204 6511 3 1299.593565 434.2059 Protein LSM14 homolog A OS=Homo sapiens OX=9606 GN=LSM14A PE=1 SV=3 4.56 1622.3 - 1.33E+06 - - - -1.7452 - 1.59 0.365 - 78.4 1 1 0 -0.0023 11 0 0 0 9.71E+07 9.43E+07 - - - 3.9261 0.7997 221125_WJC_METTL3_EV_vs_WT_F07.06516.06516.2 8.26E-06 22-Oct F.GNSTGGFDGQAR[166.11].Q sp|Q96PK6|RBM14_HUMAN 1 1175.5195 1.92 95206 6516 2 1175.512355 588.767 RNA-binding protein 14 OS=Homo sapiens OX=9606 GN=RBM14 PE=1 SV=2 5.84 1622.9 - 508625 - - - -6.0637 - 2.112 0.564 - 398.1 1 1 0 -0.0071 12 0 0 0 5.71E+07 2.98E+07 - - - 5.1716 0.9974 221125_WJC_METTL3_EV_vs_WT_F07.06529.06529.2 0.914 14-Oct R.RQQEEILR.R "sp|Q6Y7W6|GGYF2_HUMAN,tr|A0A7I2V3H7|A0A7I2V3H7_HUMAN,tr|I1E4Y6|I1E4Y6_HUMAN,tr|A0A7I2V516|A0A7I2V516_HUMAN,tr|A0A7I2V3H0|A0A7I2V3H0_HUMAN,tr|C9JHW1|C9JHW1_HUMAN,tr|A0A7I2V361|A0A7I2V361_HUMAN,tr|E7ESB6|E7ESB6_HUMAN" 8 1070.5833 1.87 95211 6529 2 1070.581813 536.2989 GRB10-interacting GYF protein 2 OS=Homo sapiens OX=9606 GN=GIGYF2 PE=1 SV=1 6.14 1624.3 - 1.32E+06 - - - -1.3479 - 1.704 0.164 - 214.9 1 2 0 -0.0014 8 0 0 0 2.69E+07 1.44E+07 - - - 1.8593 0.9554 221125_WJC_METTL3_EV_vs_WT_F07.06530.06530.2 1.37 20-Oct K.IDR[166.11]TDAISEEK[136.11].L "sp|Q9NR31|SAR1A_HUMAN,tr|H0Y5E8|H0Y5E8_HUMAN" 2 1293.6531 1.13 95212 6530 2 1293.656183 647.8338 GTP-binding protein SAR1a OS=Homo sapiens OX=9606 GN=SAR1A PE=1 SV=1 4.32 1624.4 - 858714 - - - 2.36 - 1.929 0.17 - 349 1 2 1 0.0031 11 0 0 0 1.54E+08 1.37E+08 - - - 2.073 0.9909 221125_WJC_METTL3_EV_vs_WT_F07.06535.06535.2 0.0132 13/20 K.IDRTDAISEEK.L "sp|Q9NR31|SAR1A_HUMAN,tr|H0Y5E8|H0Y5E8_HUMAN" 2 1275.6307 1.13 95214 6535 2 1275.63133 638.8226 GTP-binding protein SAR1a OS=Homo sapiens OX=9606 GN=SAR1A PE=1 SV=1 4.32 1625 - 1.28E+06 - - - 0.5252 - 2.31 0.18 - 564.6 1 2 1 0.0007 11 0 0 0 1.54E+08 1.37E+08 - - - 2.6352 1 221125_WJC_METTL3_EV_vs_WT_F07.06542.06542.2 7.08E-08 22-Dec F.GNSTGGFDGQAR.Q sp|Q96PK6|RBM14_HUMAN 1 1165.5112 1.92 95218 6542 2 1165.509604 583.7629 RNA-binding protein 14 OS=Homo sapiens OX=9606 GN=RBM14 PE=1 SV=2 5.84 1625.8 - 1.82E+06 - - - -1.3805 - 2.491 0.651 - 619.2 1 1 0 -0.0016 12 0 0 0 5.71E+07 2.98E+07 - - - 6.2502 0.9981 221125_WJC_METTL3_EV_vs_WT_F07.06544.06544.2 0.000173 18-Aug R.DDFSSGTSSR.S "sp|P43304|GPDM_HUMAN,tr|F5GYK7|F5GYK7_HUMAN" 2 1057.4312 1.06 95220 6544 2 1057.436385 529.7229 "Glycerol-3-phosphate dehydrogenase, mitochondrial OS=Homo sapiens OX=9606 GN=GPD2 PE=1 SV=3" 4.21 1626.1 - 514665 - - - 4.8731 - 1.761 0.603 - 160 1 2 0 0.0052 10 0 0 0 5.81E+06 5.47E+06 - - - 5.0727 0.9991 221125_WJC_METTL3_EV_vs_WT_F07.06545.06545.2 0.00888 16-Jun R.ASYDDPYK[136.11]K[136.11].A sp|Q96PK6|RBM14_HUMAN 1 1101.5313 1.94 95221 6545 2 1101.533155 551.7729 RNA-binding protein 14 OS=Homo sapiens OX=9606 GN=RBM14 PE=1 SV=2 6 1626.2 - 381051 - - - 1.6477 - 1.382 0.41 - 111.9 1 2 0 0.0018 9 0 0 0 1.04E+09 5.40E+08 - - - 3.0047 0.9996 221125_WJC_METTL3_EV_vs_WT_F07.06546.06546.2 4.54E-06 16-Sep K.THYQADIER.M "sp|O95573|ACSL3_HUMAN,tr|A0A7P0TBB1|A0A7P0TBB1_HUMAN,tr|A0A7P0TA76|A0A7P0TA76_HUMAN,tr|A0A7P0T8L6|A0A7P0T8L6_HUMAN" 4 1131.5309 0.6 95222 6546 2 1131.531157 566.7727 Fatty acid CoA ligase Acsl3 OS=Homo sapiens OX=9606 GN=ACSL3 PE=1 SV=3 5.29 1626.3 - 324104 - - - 0.2395 - 1.92 0.304 - 408.3 1 2 0 0.0003 9 0 0 0 1.50E+07 2.50E+07 - - - 3.1735 0.9829 221125_WJC_METTL3_EV_vs_WT_F07.06549.06549.3 0.0222 Oct-40 K.IDR[166.11]TDAISEEK[136.11].L "sp|Q9NR31|SAR1A_HUMAN,tr|H0Y5E8|H0Y5E8_HUMAN" 2 1293.6531 1.13 95223 6549 3 1293.650215 432.225 GTP-binding protein SAR1a OS=Homo sapiens OX=9606 GN=SAR1A PE=1 SV=1 4.32 1626.7 - 1.43E+07 - - - -2.2533 - 1.795 0.244 - 189.3 1 2 1 -0.0029 11 0 0 0 5.84E+08 5.15E+08 - - - 2.9215 0.8433 221125_WJC_METTL3_EV_vs_WT_F07.06550.06550.3 0.041 Sep-40 K.IDRTDAISEEK.L "sp|Q9NR31|SAR1A_HUMAN,tr|H0Y5E8|H0Y5E8_HUMAN" 2 1275.6307 1.13 95224 6550 3 1275.629461 426.2175 GTP-binding protein SAR1a OS=Homo sapiens OX=9606 GN=SAR1A PE=1 SV=1 4.32 1626.7 - 1.27E+07 - - - -0.9399 - 1.692 0.087 - 163.6 1 2 1 -0.0012 11 0 0 0 5.84E+08 5.15E+08 - - - 1.0037 0.9998 221125_WJC_METTL3_EV_vs_WT_F07.06553.06553.2 9.16E-07 18-Nov K.NQC[160.03]TQVVQER[166.11].E sp|P15924|DESP_HUMAN 1 1270.5964 27.58 95226 6553 2 1270.594108 636.3055 Desmoplakin OS=Homo sapiens OX=9606 GN=DSP PE=1 SV=3 5.99 1627.1 - 558474 - - - -1.7677 - 2.456 0.502 - 786.2 1 2 0 -0.0022 10 0 0 0 2.77E+08 1.00E+07 - - - 5.2561 0.9997 221125_WJC_METTL3_EV_vs_WT_F07.06554.06554.2 0.000157 18-Sep R.VNHVTLSQPK.L "sp|P61769|B2MG_HUMAN,tr|H0YLF3|H0YLF3_HUMAN,tr|F5H6I0|F5H6I0_HUMAN" 3 1121.6193 2.41 95227 6554 2 1121.619151 561.8169 Beta-2-microglobulin OS=Homo sapiens OX=9606 GN=B2M PE=1 SV=1 8.73 1627.3 - 527432 - - - -0.1391 - 1.642 0.43 - 246 1 2 0 -0.0002 10 0 0 0 1.44E+07 5.99E+06 - - - 3.6012 0.9886 221125_WJC_METTL3_EV_vs_WT_F07.06556.06556.3 0.225 Aug-44 R.GAFGK[136.11]PQGTVAR[166.11].V "sp|P27635|RL10_HUMAN,sp|Q96L21|RL10L_HUMAN,tr|H7C123|H7C123_HUMAN,tr|H7C2C5|H7C2C5_HUMAN,tr|F8W7C6|F8W7C6_HUMAN,tr|X1WI28|X1WI28_HUMAN" 6 1205.6636 1.3 95229 6556 3 1205.664 402.8951 60S ribosomal protein L10 OS=Homo sapiens OX=9606 GN=RPL10 PE=1 SV=4 11 1627.5 - 365657 - - - 0.3525 - 1.442 0.195 - 59.1 1 2 0 0.0004 12 0 0 0 3.78E+07 2.92E+07 - - - 1.7285 0.9997 221125_WJC_METTL3_EV_vs_WT_F07.06560.06560.2 0.00669 12-Jul R.DDWEEKR.H "sp|P43243|MATR3_HUMAN,tr|A8MXP9|A8MXP9_HUMAN,tr|D6R991|D6R991_HUMAN,tr|A0A0R4J2E8|A0A0R4J2E8_HUMAN,tr|D6REM6|D6REM6_HUMAN" 5 976.425 1.29 95231 6560 2 976.424307 489.2198 Matrin-3 OS=Homo sapiens OX=9606 GN=MATR3 PE=1 SV=2 4.32 1627.9 - 4.52E+06 - - - -0.7343 - 1.492 0.463 - 227.8 1 2 0 -0.0007 7 0 0 0 1.92E+09 1.49E+09 - - - 3.7283 1 221125_WJC_METTL3_EV_vs_WT_F07.06561.06561.3 3.55E-06 Nov-32 K.THYQADIER[166.11].M "sp|O95573|ACSL3_HUMAN,tr|A0A7P0TBB1|A0A7P0TBB1_HUMAN,tr|A0A7P0TA76|A0A7P0TA76_HUMAN,tr|A0A7P0T8L6|A0A7P0T8L6_HUMAN" 4 1141.5392 0.001 95232 6561 3 1141.537273 381.5203 Fatty acid CoA ligase Acsl3 OS=Homo sapiens OX=9606 GN=ACSL3 PE=1 SV=3 5.29 1628 - 1.75E+06 - - - -1.6495 - 2.491 0.498 - 347.8 1 2 0 -0.0019 9 0 0 0 0.00E+00 3.47E+07 - - - 6.8423 0.9906 221125_WJC_METTL3_EV_vs_WT_F07.06563.06563.2 0.00018 18-Nov R.TSNEVQYDQR[166.11].L "sp|Q13573|SNW1_HUMAN,tr|G3V4X8|G3V4X8_HUMAN,tr|G3V3A4|G3V3A4_HUMAN" 3 1248.561 0.95 95234 6563 2 1248.551683 625.2878 SNW domain-containing protein 1 OS=Homo sapiens OX=9606 GN=SNW1 PE=1 SV=1 4.37 1628.2 - 1.21E+06 - - - -7.4734 - 2.178 0.562 - 516.2 1 2 0 -0.0093 10 0 0 0 4.67E+07 4.89E+07 - - - 5.3618 0.999 221125_WJC_METTL3_EV_vs_WT_F07.06569.06569.2 0.0168 16-Oct R.KLLEGEEC[160.03]R.M "sp|Q86Y46|K2C73_HUMAN,sp|Q7RTS7|K2C74_HUMAN,sp|P48668|K2C6C_HUMAN,sp|Q01546|K22O_HUMAN,sp|P12036|NFH_HUMAN,sp|P04259|K2C6B_HUMAN,sp|P13647|K2C5_HUMAN,sp|P35908|K22E_HUMAN,sp|O95678|K2C75_HUMAN,sp|P02538|K2C6A_HUMAN,tr|H0YI76|H0YI76_HUMAN,tr|H0YIC5|H0YIC5_HUMAN,tr|F8W1S1|F8W1S1_HUMAN" 13 1132.5547 7.83 95237 6569 2 1132.558258 567.2846 "Keratin, type II cytoskeletal 73 OS=Homo sapiens OX=9606 GN=KRT73 PE=1 SV=1" 4.79 1628.9 - 628994 - - - 3.1787 - 1.996 0.427 - 450.9 1 2 0 0.0036 9 0 0 0 8.65E+07 1.10E+07 - - - 4.1932 0.8078 221125_WJC_METTL3_EV_vs_WT_F07.06578.06578.2 0.000868 18-Dec L.DR[166.11]TDAISEEK[136.11].L "sp|Q9NR31|SAR1A_HUMAN,tr|H0Y5E8|H0Y5E8_HUMAN" 2 1180.5691 2.42 95243 6578 2 1180.568127 591.2918 GTP-binding protein SAR1a OS=Homo sapiens OX=9606 GN=SAR1A PE=1 SV=1 4.32 1629.9 - 883647 - - - -0.7954 - 2.361 0.28 - 558.9 1 1 1 -0.0009 10 0 0 0 3.10E+07 1.28E+07 - - - 3.5068 0.9986 221125_WJC_METTL3_EV_vs_WT_F07.06579.06579.2 0.00266 16-Aug K.THYQADIER[166.11].M "sp|O95573|ACSL3_HUMAN,tr|A0A7P0TBB1|A0A7P0TBB1_HUMAN,tr|A0A7P0TA76|A0A7P0TA76_HUMAN,tr|A0A7P0T8L6|A0A7P0T8L6_HUMAN" 4 1141.5392 0.65 95244 6579 2 1141.539217 571.7769 Fatty acid CoA ligase Acsl3 OS=Homo sapiens OX=9606 GN=ACSL3 PE=1 SV=3 5.29 1630.1 - 821248 - - - 0.0534 - 1.538 0.241 - 285.1 1 2 0 0.0001 9 0 0 0 1.46E+07 2.26E+07 - - - 2.0664 0.9998 221125_WJC_METTL3_EV_vs_WT_F07.06594.06594.3 0.000387 Nov-32 R.C[160.03]REMDEQIR.L "tr|A0A2R2Y2Q3|A0A2R2Y2Q3_HUMAN,tr|A0A087WWU8|A0A087WWU8_HUMAN,tr|J3KN67|J3KN67_HUMAN,tr|A0A494C0P6|A0A494C0P6_HUMAN" 4 1235.5387 1.32 95254 6594 3 1235.53645 412.8535 Tropomyosin 3 nu OS=Homo sapiens OX=9606 GN=TPM3 PE=1 SV=1 4.68 1631.9 - 579120 - - - -1.8138 - 1.853 0.558 - 170.7 1 2 1 -0.0022 9 0 0 0 1.69E+07 1.28E+07 - - - 6.6195 0.9981 221125_WJC_METTL3_EV_vs_WT_F07.06595.06595.2 5.11E-06 13/24 K.SGAEVEAGDAAER[166.11].R "sp|Q8IY67|RAVR1_HUMAN,tr|K7EKR9|K7EKR9_HUMAN,tr|E9PAU2|E9PAU2_HUMAN,tr|A0A087WZ13|A0A087WZ13_HUMAN" 4 1270.5665 0.5 95255 6595 2 1270.559978 636.2905 Ribonucleoprotein PTB-binding 1 OS=Homo sapiens OX=9606 GN=RAVER1 PE=1 SV=1 4 1632.1 - 357859 - - - -5.1276 - 2.669 0.527 - 667 1 2 0 -0.0065 13 0 0 0 9.81E+06 1.96E+07 - - - 5.4509 0.9975 221125_WJC_METTL3_EV_vs_WT_F07.06602.06602.2 0.023 16-Aug K.TNR[166.11]PFISQK[136.11].L "sp|O75530|EED_HUMAN,tr|A0A5F9ZI63|A0A5F9ZI63_HUMAN" 2 1107.6156 1.84 95260 6602 2 1107.61289 554.8151 Polycomb protein EED OS=Homo sapiens OX=9606 GN=EED PE=1 SV=2 11 1632.9 - 281117 - - - -2.4133 - 1.529 0.3 - 229 1 2 0 -0.0027 9 0 0 0 1.10E+07 5.98E+06 - - - 2.4844 0.9955 221125_WJC_METTL3_EV_vs_WT_F07.06603.06603.2 0.000341 18-Jul K.YMEENDQLK[136.11]K[136.11].G "sp|P51572|BAP31_HUMAN,tr|A0A2R8Y5M6|A0A2R8Y5M6_HUMAN,tr|C9J0M4|C9J0M4_HUMAN,tr|C9JQ75|C9JQ75_HUMAN,tr|C9JSP1|C9JSP1_HUMAN,tr|C9JMD7|C9JMD7_HUMAN" 6 1312.6304 1.24 95261 6603 2 1312.629598 657.3225 B-cell receptor-associated protein 31 OS=Homo sapiens OX=9606 GN=BCAP31 PE=1 SV=3 4.68 1633.1 - 178363 - - - -0.6125 - 1.373 0.174 - 140.5 1 2 0 -0.0008 10 0 0 0 3.48E+06 2.82E+06 - - - 1.2107 0.885 221125_WJC_METTL3_EV_vs_WT_F07.06609.06609.3 0.0947 Oct-32 W.SQHYHQGYY.- "sp|Q00839|HNRPU_HUMAN,tr|A0A1W2PPL4|A0A1W2PPL4_HUMAN,tr|A0A087WVI9|A0A087WVI9_HUMAN,tr|Q5RI18|Q5RI18_HUMAN,tr|A0A1W2PP35|A0A1W2PP35_HUMAN,tr|A0A1W2PPH7|A0A1W2PPH7_HUMAN,tr|A0A1W2PQD4|A0A1W2PQD4_HUMAN,tr|A0A1X7SBS1|A0A1X7SBS1_HUMAN" 8 1181.489 - 95265 6609 3 1181.488933 394.837 Heterogeneous nuclear ribonucleoprotein U OS=Homo sapiens OX=9606 GN=HNRNPU PE=1 SV=6 6.66 1633.8 - 1.12E+06 - - - -0.0745 - 1.511 0.303 - 69.9 1 1 0 -0.0001 9 0 0 0 - - - - - 3.1621 0.942 221125_WJC_METTL3_EV_vs_WT_F07.06616.06616.2 1.04 16-Aug W.SQHYHQGYY.- "sp|Q00839|HNRPU_HUMAN,tr|A0A1W2PPL4|A0A1W2PPL4_HUMAN,tr|A0A087WVI9|A0A087WVI9_HUMAN,tr|Q5RI18|Q5RI18_HUMAN,tr|A0A1W2PP35|A0A1W2PP35_HUMAN,tr|A0A1W2PPH7|A0A1W2PPH7_HUMAN,tr|A0A1W2PQD4|A0A1W2PQD4_HUMAN,tr|A0A1X7SBS1|A0A1X7SBS1_HUMAN" 8 1181.489 - 95267 6616 2 1181.490595 591.7518 Heterogeneous nuclear ribonucleoprotein U OS=Homo sapiens OX=9606 GN=HNRNPU PE=1 SV=6 6.66 1634.6 - 963820 - - - 1.3322 - 1.593 0.321 - 162.4 1 1 0 0.0016 9 0 0 0 - - - - - 2.7585 0.9994 221125_WJC_METTL3_EV_vs_WT_F07.06624.06624.2 0.000395 18-Dec R.TSNEVQYDQR.L "sp|Q13573|SNW1_HUMAN,tr|G3V4X8|G3V4X8_HUMAN,tr|G3V3A4|G3V3A4_HUMAN" 3 1238.5527 0.95 95273 6624 2 1238.557032 620.2836 SNW domain-containing protein 1 OS=Homo sapiens OX=9606 GN=SNW1 PE=1 SV=1 4.37 1635.5 - 1.83E+06 - - - 3.4621 - 2.517 0.512 - 649.9 1 2 0 0.0043 10 0 0 0 4.67E+07 4.89E+07 - - - 5.3978 0.9998 221125_WJC_METTL3_EV_vs_WT_F07.06625.06625.3 1.58E-05 Sep-32 R.C[160.03]R[166.11]EMDEQIR[166.11].L "tr|A0A2R2Y2Q3|A0A2R2Y2Q3_HUMAN,tr|A0A087WWU8|A0A087WWU8_HUMAN,tr|J3KN67|J3KN67_HUMAN,tr|A0A494C0P6|A0A494C0P6_HUMAN" 4 1255.5552 1.34 95274 6625 3 1255.553339 419.5257 Tropomyosin 3 nu OS=Homo sapiens OX=9606 GN=TPM3 PE=1 SV=1 4.68 1635.7 - 562038 - - - -1.5069 - 1.873 0.516 - 157.8 1 2 1 -0.0019 9 0 0 0 1.67E+07 1.25E+07 - - - 6.1836 0.9999 221125_WJC_METTL3_EV_vs_WT_F07.06630.06630.2 0.000466 14/24 K.SGAEVEAGDAAER.R "sp|Q8IY67|RAVR1_HUMAN,tr|K7EKR9|K7EKR9_HUMAN,tr|E9PAU2|E9PAU2_HUMAN,tr|A0A087WZ13|A0A087WZ13_HUMAN" 4 1260.5582 0.5 95277 6630 2 1260.557287 631.2864 Ribonucleoprotein PTB-binding 1 OS=Homo sapiens OX=9606 GN=RAVER1 PE=1 SV=1 4 1636.3 - 667167 - - - -0.7425 - 2.782 0.542 - 849.5 1 2 0 -0.0009 13 0 0 0 9.81E+06 1.96E+07 - - - 5.6699 0.7754 221125_WJC_METTL3_EV_vs_WT_F07.06636.06636.3 0.318 Sep-40 R.EVR[166.11]PDTQYTGR[166.11].K "sp|O43709|BUD23_HUMAN,tr|H7C0G4|H7C0G4_HUMAN" 2 1340.6588 2.55 95281 6636 3 1340.656234 447.8935 Probable 18S rRNA (guanine-N(7))-methyltransferase OS=Homo sapiens OX=9606 GN=BUD23 PE=1 SV=2 6.17 1637 - 1.41E+06 - - - -1.8901 - 1.593 0.031 - 144.2 1 2 0 -0.0025 11 0 0 0 1.36E+08 5.33E+07 - - - 0.2077 0.9902 221125_WJC_METTL3_EV_vs_WT_F07.06639.06639.2 3.56E-06 28-Dec A.GGPAPSTAAAPAEEK.K sp|P05386|RLA1_HUMAN 1 1352.6572 1.56 95284 6639 2 1352.659577 677.3359 60S acidic ribosomal protein P1 OS=Homo sapiens OX=9606 GN=RPLP1 PE=1 SV=1 4.53 1637.4 - 546362 - - - 1.7506 - 2.253 0.628 - 362.8 1 1 0 0.0024 15 0 0 0 1.12E+08 7.16E+07 - - - 5.6756 0.9991 221125_WJC_METTL3_EV_vs_WT_F07.06640.06640.2 3.12E-05 26-Aug K.K[136.11]GPGEVAGTVTGQK[136.11].R "sp|Q86U44|MTA70_HUMAN,tr|F5H6D8|F5H6D8_HUMAN,tr|H0YFV6|H0YFV6_HUMAN,tr|B4DTN4|B4DTN4_HUMAN" 4 1343.738 0.001 95285 6640 2 1343.733891 672.8763 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 8.59 1637.5 - 194948 - - - -3.0423 - 1.911 0.459 - 109.7 1 2 0 -0.0041 14 0 0 0 0.00E+00 1.77E+08 - - - 4.0551 0.9717 221125_WJC_METTL3_EV_vs_WT_F07.06644.06644.2 6.32E-06 28-Oct A.GGPAPSTAAAPAEEK[136.11].K sp|P05386|RLA1_HUMAN 1 1360.6714 1.56 95287 6644 2 1360.667959 681.343 60S acidic ribosomal protein P1 OS=Homo sapiens OX=9606 GN=RPLP1 PE=1 SV=1 4.53 1638 - 376183 - - - -2.5355 - 1.924 0.518 - 227.9 1 1 0 -0.0034 15 0 0 0 1.12E+08 7.16E+07 - - - 4.4748 0.9999 221125_WJC_METTL3_EV_vs_WT_F07.06655.06655.2 0.000122 22-Dec R.NTDVAQSPEAPK.Q "sp|Q9P2E9|RRBP1_HUMAN,tr|A0A087WVV2|A0A087WVV2_HUMAN,tr|V9GY78|V9GY78_HUMAN" 3 1255.6044 2.02 95295 6655 2 1255.605467 628.8095 Ribosome-binding protein 1 OS=Homo sapiens OX=9606 GN=RRBP1 PE=1 SV=5 4.37 1639.2 - 665279 - - - 0.814 - 2.697 0.48 - 576.3 1 2 0 0.001 12 0 0 0 1.51E+07 7.47E+06 - - - 5.1964 0.9915 221125_WJC_METTL3_EV_vs_WT_F07.06658.06658.2 0.0313 16-Jun R.EESTTGFDK.S "sp|Q9Y2W1|TR150_HUMAN,tr|A0A3B3ITZ9|A0A3B3ITZ9_HUMAN" 2 1012.4349 3.86 95297 6658 2 1012.439066 507.2247 Thyroid hormone receptor-associated protein 3 OS=Homo sapiens OX=9606 GN=THRAP3 PE=1 SV=2 4.14 1639.6 - 201277 - - - 4.0951 - 1.285 0.374 - 87.7 1 2 0 0.0041 9 0 0 0 2.89E+06 7.50E+05 - - - 2.5275 1 221125_WJC_METTL3_EV_vs_WT_F07.06667.06667.2 6.21E-05 24-Dec R.TVAATNMNETSSR[166.11].S "sp|O43896|KIF1C_HUMAN,sp|O60333|KIF1B_HUMAN,sp|Q12756|KIF1A_HUMAN,tr|A0A3B3ITW6|A0A3B3ITW6_HUMAN,tr|A0A3B3ITF7|A0A3B3ITF7_HUMAN,tr|A0A3B3ITE5|A0A3B3ITE5_HUMAN,tr|A0A3B3IUA1|A0A3B3IUA1_HUMAN,tr|A0A3B3IT28|A0A3B3IT28_HUMAN,tr|A0A087WWA3|A0A087WWA3_HUMAN,tr|A0A3F2YNW9|A0A3F2YNW9_HUMAN,tr|H7C0K6|H7C0K6_HUMAN,tr|A0A3B3IU40|A0A3B3IU40_HUMAN,tr|Q4R9M9|Q4R9M9_HUMAN" 13 1390.6386 0.92 95304 6667 2 1390.638908 696.3266 Kinesin-like protein KIF1C OS=Homo sapiens OX=9606 GN=KIF1C PE=1 SV=3 5.66 1640.9 - 327680 - - - 0.2129 - 2.629 0.593 - 367.8 1 2 0 0.0003 13 0 0 0 1.02E+07 1.11E+07 - - - 5.9016 0.9718 221125_WJC_METTL3_EV_vs_WT_F07.06668.06668.2 0.0438 20-Apr R.EVRPDTQYTGR.K "sp|O43709|BUD23_HUMAN,tr|H7C0G4|H7C0G4_HUMAN" 2 1320.6422 1.84 95305 6668 2 1320.637849 661.3284 Probable 18S rRNA (guanine-N(7))-methyltransferase OS=Homo sapiens OX=9606 GN=BUD23 PE=1 SV=2 6.17 1641 - 151503 - - - -3.3158 - 1.286 0.236 - 26.4 7 2 0 -0.0044 11 0 0 0 4.20E+06 2.28E+06 - - - 1.0857 0.9996 221125_WJC_METTL3_EV_vs_WT_F07.06672.06672.3 9.32E-06 Dec-36 K.NKYEDEINKR.T "sp|P48668|K2C6C_HUMAN,sp|P05787|K2C8_HUMAN,sp|P04264|K2C1_HUMAN,sp|P04259|K2C6B_HUMAN,sp|P13647|K2C5_HUMAN,sp|P02538|K2C6A_HUMAN,tr|F8VUG2|F8VUG2_HUMAN,tr|F8W0C6|F8W0C6_HUMAN,tr|F8VP67|F8VP67_HUMAN,tr|F8W1U3|F8W1U3_HUMAN" 10 1307.647 17.38 95307 6672 3 1307.648835 436.8896 "Keratin, type II cytoskeletal 6C OS=Homo sapiens OX=9606 GN=KRT6C PE=1 SV=3" 6.18 1641.4 - 1.15E+06 - - - 1.4193 - 2.248 0.417 - 169.7 1 2 1 0.0019 10 0 0 0 3.71E+07 2.13E+06 - - - 5.5543 0.8953 221125_WJC_METTL3_EV_vs_WT_F07.06673.06673.3 1.29 Oct-36 K.TYIPPK[136.11]GETK[136.11].K "sp|B2RPK0|HGB1A_HUMAN,sp|P09429|HMGB1_HUMAN,tr|Q5T7C4|Q5T7C4_HUMAN" 3 1148.6412 0.001 95308 6673 3 1148.642056 383.8877 Putative high mobility group protein B1-like 1 OS=Homo sapiens OX=9606 GN=HMGB1P1 PE=5 SV=1 8.17 1641.5 - 1.48E+06 - - - 0.7235 - 1.56 0.128 - 163.5 1 2 1 0.0008 10 0 0 0 0.00E+00 2.71E+07 - - - 1.2655 1 221125_WJC_METTL3_EV_vs_WT_F07.06674.06674.2 1.03E-06 22-Dec K.VSDGGSSSTDFK[136.11].M "sp|Q7Z6Z7|HUWE1_HUMAN,tr|A0A087X146|A0A087X146_HUMAN,tr|H0Y659|H0Y659_HUMAN" 3 1193.5292 0.65 95309 6674 2 1193.52799 597.7719 E3 ubiquitin-protein ligase HUWE1 OS=Homo sapiens OX=9606 GN=HUWE1 PE=1 SV=3 4.21 1641.6 - 622655 - - - -0.9811 - 2.555 0.633 - 578.9 1 2 0 -0.0012 12 0 0 0 1.11E+07 1.70E+07 - - - 6.1841 0.9994 221125_WJC_METTL3_EV_vs_WT_F07.06675.06675.2 2.66E-05 18-Oct R.ETQSQLETER.S sp|P15924|DESP_HUMAN 1 1219.5681 20.46 95310 6675 2 1219.569698 610.7913 Desmoplakin OS=Homo sapiens OX=9606 GN=DSP PE=1 SV=3 4.25 1641.8 - 477027 - - - 1.3431 - 1.995 0.325 - 555.3 1 2 0 0.0016 10 0 0 0 2.08E+07 1.02E+06 - - - 3.3687 0.9999 221125_WJC_METTL3_EV_vs_WT_F07.06677.06677.2 4.27E-05 24-Oct R.TVAATNMNETSSR.S "sp|O43896|KIF1C_HUMAN,sp|O60333|KIF1B_HUMAN,sp|Q12756|KIF1A_HUMAN,tr|A0A3B3ITW6|A0A3B3ITW6_HUMAN,tr|A0A3B3ITF7|A0A3B3ITF7_HUMAN,tr|A0A3B3ITE5|A0A3B3ITE5_HUMAN,tr|A0A3B3IUA1|A0A3B3IUA1_HUMAN,tr|A0A3B3IT28|A0A3B3IT28_HUMAN,tr|A0A087WWA3|A0A087WWA3_HUMAN,tr|A0A3F2YNW9|A0A3F2YNW9_HUMAN,tr|H7C0K6|H7C0K6_HUMAN,tr|A0A3B3IU40|A0A3B3IU40_HUMAN,tr|Q4R9M9|Q4R9M9_HUMAN" 13 1380.6303 0.92 95312 6677 2 1380.630114 691.3224 Kinesin-like protein KIF1C OS=Homo sapiens OX=9606 GN=KIF1C PE=1 SV=3 5.66 1642 - 277188 - - - -0.1651 - 2.062 0.545 - 257.3 1 2 0 -0.0002 13 0 0 0 1.02E+07 1.11E+07 - - - 4.9236 0.9997 221125_WJC_METTL3_EV_vs_WT_F07.06678.06678.2 0.000222 22-Aug R.ADNSSDSPTTLK[136.11].L "sp|Q5VWN6|TASO2_HUMAN,tr|J3KPH3|J3KPH3_HUMAN,tr|A0A2R8YH03|A0A2R8YH03_HUMAN" 3 1242.5819 0.96 95313 6678 2 1242.582708 622.2982 Protein TASOR 2 OS=Homo sapiens OX=9606 GN=TASOR2 PE=1 SV=1 4.21 1642.2 - 276842 - - - 0.6301 - 1.899 0.398 - 311.7 1 2 0 0.0008 12 0 0 0 5.66E+06 5.89E+06 - - - 3.6678 0.9997 221125_WJC_METTL3_EV_vs_WT_F07.06682.06682.3 0.00037 Nov-52 K.K[136.11]GPGEVAGTVTGQK[136.11].R "sp|Q86U44|MTA70_HUMAN,tr|F5H6D8|F5H6D8_HUMAN,tr|H0YFV6|H0YFV6_HUMAN,tr|B4DTN4|B4DTN4_HUMAN" 4 1343.738 0.01 95315 6682 3 1343.740403 448.9199 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 8.59 1642.6 - 1.34E+06 - - - 1.8039 - 2.362 0.349 - 215 1 2 0 0.0024 14 0 0 0 5.31E+06 4.96E+08 - - - 4.7145 1 221125_WJC_METTL3_EV_vs_WT_F07.06684.06684.2 2.09E-08 22-Nov L.DAC[160.03]MDSEAPGSK[136.11].D "sp|Q86U44|MTA70_HUMAN,tr|H0YFV6|H0YFV6_HUMAN" 2 1274.4999 0.001 95317 6684 2 1274.501455 638.2572 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 4.03 1642.8 - 397383 - - - 1.2577 - 2.179 0.766 - 364.6 1 1 0 0.0016 12 0 0 0 0.00E+00 1.06E+07 - - - 6.7475 0.9999 221125_WJC_METTL3_EV_vs_WT_F07.06687.06687.2 4.69E-05 22-Sep K.LESC[160.03]GVTSDNC[160.03]R.D sp|P13489|RINI_HUMAN 1 1396.5711 1.04 95320 6687 2 1396.570198 699.2928 Ribonuclease inhibitor OS=Homo sapiens OX=9606 GN=RNH1 PE=1 SV=2 4.37 1643.2 - 193586 - - - -0.6552 - 1.832 0.636 - 296.4 1 2 0 -0.0009 12 0 0 0 7.09E+06 6.84E+06 - - - 5.3311 0.9998 221125_WJC_METTL3_EV_vs_WT_F07.06688.06688.2 0.000542 22-Jul K.LESC[160.03]GVTSDNC[160.03]R[166.11].D sp|P13489|RINI_HUMAN 1 1406.5794 1.04 95321 6688 2 1406.580062 704.297 Ribonuclease inhibitor OS=Homo sapiens OX=9606 GN=RNH1 PE=1 SV=2 4.37 1643.3 - 148947 - - - 0.482 - 1.715 0.492 - 129.7 1 2 0 0.0007 12 0 0 0 7.09E+06 6.84E+06 - - - 4.094 0.9995 221125_WJC_METTL3_EV_vs_WT_F07.06689.06689.2 0.00174 16-Aug R.QVDQLTNDK.A "sp|P08670|VIME_HUMAN,tr|B0YJC4|B0YJC4_HUMAN" 2 1059.5197 41.85 95322 6689 2 1059.520202 530.7671 Vimentin OS=Homo sapiens OX=9606 GN=VIM PE=1 SV=4 4.21 1643.5 - 137111 - - - 0.5182 - 1.666 0.34 - 252.8 1 2 0 0.0006 9 0 0 0 4.21E+07 1.01E+06 - - - 3.0288 0.9995 221125_WJC_METTL3_EV_vs_WT_F07.06692.06692.2 0.0219 14-Aug K.EHC[160.03]LVGVK[136.11].G sp|Q86U44|MTA70_HUMAN 1 948.4942 0.02 95323 6692 2 948.495368 475.2544 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 6.83 1643.9 - 1.89E+06 - - - 1.1924 - 1.549 0.424 - 346.9 1 2 0 0.0011 8 0 0 0 1.72E+07 7.63E+08 - - - 3.4921 0.9875 221125_WJC_METTL3_EV_vs_WT_F07.06702.06702.2 0.709 18-Jun R.QESPSVPSC[160.03]K[136.11].E "sp|Q5VT06|CE350_HUMAN,tr|H0Y6Q4|H0Y6Q4_HUMAN" 2 1125.5216 0.13 95329 6702 2 1125.523219 563.7681 Centrosome-associated protein 350 OS=Homo sapiens OX=9606 GN=CEP350 PE=1 SV=1 5.99 1645.2 - 492784 - - - 1.4615 - 0.88 0.289 - 79.2 1 2 0 0.0016 10 0 0 0 9.56E+05 7.43E+06 - - - 0.8182 0.9993 221125_WJC_METTL3_EV_vs_WT_F07.06709.06709.2 0.00239 14-Aug R.NISFNDK[136.11]K[136.11].F "sp|P15311|EZRI_HUMAN,sp|P26038|MOES_HUMAN,sp|P35241|RADI_HUMAN,tr|A0A2R8Y5S7|A0A2R8Y5S7_HUMAN,tr|E7EQR4|E7EQR4_HUMAN,tr|A0A2R8Y7M3|A0A2R8Y7M3_HUMAN" 6 980.5262 0.58 95332 6709 2 980.527827 491.2704 Ezrin OS=Homo sapiens OX=9606 GN=EZR PE=1 SV=4 8.59 1646.1 - 897167 - - - 1.6644 - 1.478 0.418 - 197.7 1 2 0 0.0016 8 0 0 0 2.20E+07 3.81E+07 - - - 3.3061 0.9993 221125_WJC_METTL3_EV_vs_WT_F07.06712.06712.2 0.00437 14-Aug R.NISFNDKK.F "sp|P15311|EZRI_HUMAN,sp|P26038|MOES_HUMAN,sp|P35241|RADI_HUMAN,tr|A0A2R8Y5S7|A0A2R8Y5S7_HUMAN,tr|E7EQR4|E7EQR4_HUMAN,tr|A0A2R8Y7M3|A0A2R8Y7M3_HUMAN" 6 964.4978 0.58 95335 6712 2 964.498605 483.2562 Ezrin OS=Homo sapiens OX=9606 GN=EZR PE=1 SV=4 8.59 1646.5 - 480525 - - - 0.8398 - 1.418 0.381 - 214.6 1 2 0 0.0008 8 0 0 0 2.20E+07 3.82E+07 - - - 2.9081 0.9998 221125_WJC_METTL3_EV_vs_WT_F07.06716.06716.3 0.00478 Sep-44 R.NIEEHASADVEK[136.11].M sp|P61006|RAB8A_HUMAN 1 1348.635 1.03 95337 6716 3 1348.637047 450.5523 Ras-related protein Rab-8A OS=Homo sapiens OX=9606 GN=RAB8A PE=1 SV=1 4.4 1646.9 - 1.33E+06 - - - 1.5 - 1.802 0.412 - 122.9 1 2 0 0.002 12 0 0 0 4.86E+07 4.71E+07 - - - 4.7652 0.9283 221125_WJC_METTL3_EV_vs_WT_F07.06718.06718.2 0.000179 26-Jul K.APEGGEGAQPVPGH.A "sp|Q6W2J9|BCOR_HUMAN,tr|H7BZ37|H7BZ37_HUMAN,tr|H7C2V9|H7C2V9_HUMAN,tr|H7BYY2|H7BYY2_HUMAN,tr|H7C231|H7C231_HUMAN" 5 1301.6 - 95339 6718 2 1301.603021 651.8073 BCL-6 corepressor OS=Homo sapiens OX=9606 GN=BCOR PE=1 SV=1 4.51 1647.2 - 122899 - - - 2.2987 - 1.347 0.451 - 111.5 1 1 0 0.003 14 0 0 0 - - - - - 3.1187 0.9997 221125_WJC_METTL3_EV_vs_WT_F07.06721.06721.3 0.00348 Nov-44 R.NIEEHASADVEK.M sp|P61006|RAB8A_HUMAN 1 1340.6208 1.02 95340 6721 3 1340.624695 447.8809 Ras-related protein Rab-8A OS=Homo sapiens OX=9606 GN=RAB8A PE=1 SV=1 4.4 1647.6 - 1.61E+06 - - - 2.8875 - 1.996 0.429 - 210.9 1 2 0 0.0039 12 0 0 0 4.73E+07 4.62E+07 - - - 5.2376 0.9867 221125_WJC_METTL3_EV_vs_WT_F07.06722.06722.2 1.33E-05 18-Oct K.QK[136.11]LEEDAEMK[136.11].S sp|P05455|LA_HUMAN 1 1235.6039 2.2 95341 6722 2 1235.608249 618.8092 Lupus La protein OS=Homo sapiens OX=9606 GN=SSB PE=1 SV=2 4.41 1647.7 - 357846 - - - 3.5578 - 1.795 0.488 - 327.8 1 2 1 0.0044 10 0 0 0 3.00E+07 1.36E+07 - - - 4.2769 0.9997 221125_WJC_METTL3_EV_vs_WT_F07.06723.06723.2 4.29E-06 16-Aug K.SYSEDDIHR[166.11].S "sp|Q9Y5A9|YTHD2_HUMAN,sp|Q9BYJ9|YTHD1_HUMAN,sp|Q7Z739|YTHD3_HUMAN,tr|A0A087X0Q1|A0A087X0Q1_HUMAN,tr|A0A024R7W5|A0A024R7W5_HUMAN,tr|A0A087WY31|A0A087WY31_HUMAN" 6 1130.4868 1.44 95342 6723 2 1130.488955 566.2507 YTH domain-containing family protein 2 OS=Homo sapiens OX=9606 GN=YTHDF2 PE=1 SV=2 4.53 1647.8 - 274013 - - - 1.9186 - 1.776 0.55 - 202.8 1 2 0 0.0022 9 0 0 0 1.41E+08 9.81E+07 - - - 4.7643 0.8079 221125_WJC_METTL3_EV_vs_WT_F07.06729.06729.2 0.062 24-Jun R.VESVEPSENEASK.E sp|Q9H307|PININ_HUMAN 1 1403.6416 0.61 95345 6729 2 1404.642907 702.8281 Pinin OS=Homo sapiens OX=9606 GN=PNN PE=1 SV=5 4.09 1648.6 - 129699 - - - 713.3502 - 1.476 0.214 - 55.7 1 2 0 1.0013 13 0 0 0 1.07E+07 1.77E+07 - - - 1.3064 0.9846 221125_WJC_METTL3_EV_vs_WT_F07.06734.06734.3 0.036 Jul-48 K.TTAEAYHAGMC[160.03]SR.E "sp|O94761|RECQ4_HUMAN,tr|A0A087X072|A0A087X072_HUMAN,tr|V9GZ64|V9GZ64_HUMAN" 3 1453.6078 2.28 95347 6734 3 1453.611007 485.5432 ATP-dependent DNA helicase Q4 OS=Homo sapiens OX=9606 GN=RECQL4 PE=1 SV=2 6.41 1649.2 - 212842 - - - 2.1835 - 1.135 0.281 - 57.7 1 2 0 0.0032 13 0 0 0 5.19E+06 2.27E+06 - - - 2.0153 0.9996 221125_WJC_METTL3_EV_vs_WT_F07.06739.06739.2 3.39E-05 20-Sep R.TTSNNTYEVEK.T "sp|O14802|RPC1_HUMAN,tr|Q7Z755|Q7Z755_HUMAN" 2 1284.5834 0.49 95350 6739 2 1284.580031 643.299 DNA-directed RNA polymerase III subunit RPC1 OS=Homo sapiens OX=9606 GN=POLR3A PE=1 SV=2 4.53 1649.8 - 147666 - - - -2.6032 - 1.939 0.537 - 279.5 1 2 0 -0.0033 11 0 0 0 4.18E+06 8.50E+06 - - - 4.7976 0.8453 221125_WJC_METTL3_EV_vs_WT_F07.06740.06740.2 0.291 18-Aug K.DQLPADEC[160.03]NK[136.11].L "sp|P38646|GRP75_HUMAN,tr|A0A7I2V2S7|A0A7I2V2S7_HUMAN,tr|A0A7I2V2G2|A0A7I2V2G2_HUMAN,tr|A0A7I2V3F7|A0A7I2V3F7_HUMAN,tr|A0A7I2YQB2|A0A7I2YQB2_HUMAN,tr|D6RCD7|D6RCD7_HUMAN" 6 1196.5223 0.41 95351 6740 2 1197.523362 599.2684 "Stress-70 protein, mitochondrial OS=Homo sapiens OX=9606 GN=HSPA9 PE=1 SV=2" 4.03 1649.9 - 193121 - - - 836.6413 - 1.701 0.205 - 161.4 1 2 0 1.0011 10 0 0 0 1.48E+07 3.66E+07 - - - 1.7236 0.9975 221125_WJC_METTL3_EV_vs_WT_F07.06747.06747.2 1.79 18-May K.R[166.11]GAAGDWGER[166.11].A "sp|Q14978|NOLC1_HUMAN,tr|A0A0A0MRM9|A0A0A0MRM9_HUMAN" 2 1093.5168 1.97 95356 6747 2 1093.518037 547.7657 Nucleolar and coiled-body phosphoprotein 1 OS=Homo sapiens OX=9606 GN=NOLC1 PE=1 SV=2 6.07 1650.8 - 276708 - - - 1.1358 - 1.292 0.306 - 50.2 2 2 0 0.0012 10 0 0 0 5.04E+07 2.56E+07 - - - 1.8814 0.9975 221125_WJC_METTL3_EV_vs_WT_F07.06750.06750.2 0.0371 22-Jul K.TDNVEVTDGENK.E "sp|Q92576|PHF3_HUMAN,tr|E7ER40|E7ER40_HUMAN" 2 1319.5841 2.1 95359 6750 2 1319.586882 660.7993 PHD finger protein 3 OS=Homo sapiens OX=9606 GN=PHF3 PE=1 SV=3 3.92 1651.1 - 96410.2 - - - 2.1052 - 1.486 0.308 - 84.9 1 2 0 0.0028 12 0 0 0 3.04E+06 1.45E+06 - - - 2.3572 0.9996 221125_WJC_METTL3_EV_vs_WT_F07.06752.06752.2 5.96E-05 20-Nov K.ESQSPDTTIQR.T "sp|Q92973|TNPO1_HUMAN,tr|A0A7P0T9C0|A0A7P0T9C0_HUMAN,tr|A0A7P0TBF0|A0A7P0TBF0_HUMAN,tr|E7EW37|E7EW37_HUMAN,tr|A0A7P0T944|A0A7P0T944_HUMAN,tr|A0A7P0Z4D3|A0A7P0Z4D3_HUMAN" 6 1260.5946 0.51 95360 6752 2 1260.595621 631.3046 Transportin-1 OS=Homo sapiens OX=9606 GN=TNPO1 PE=1 SV=2 4.37 1651.4 - 1.25E+06 - - - 0.8028 - 1.98 0.338 - 403.8 1 2 0 0.001 11 0 0 0 2.75E+07 5.41E+07 - - - 3.3851 0.9998 221125_WJC_METTL3_EV_vs_WT_F07.06755.06755.2 8.96E-06 16-Sep K.SYSEDDIHR.S "sp|Q9Y5A9|YTHD2_HUMAN,sp|Q9BYJ9|YTHD1_HUMAN,sp|Q7Z739|YTHD3_HUMAN,tr|A0A087X0Q1|A0A087X0Q1_HUMAN,tr|A0A024R7W5|A0A024R7W5_HUMAN,tr|A0A087WY31|A0A087WY31_HUMAN" 6 1120.4785 1.44 95362 6755 2 1120.480452 561.2465 YTH domain-containing family protein 2 OS=Homo sapiens OX=9606 GN=YTHDF2 PE=1 SV=2 4.53 1651.6 - 4.27E+06 - - - 1.7278 - 1.784 0.639 - 245.8 1 2 0 0.0019 9 0 0 0 1.41E+08 9.81E+07 - - - 5.4347 0.9879 221125_WJC_METTL3_EV_vs_WT_F07.06758.06758.2 0.00085 14-Aug S.YSEDDIHR.S "sp|Q9Y5A9|YTHD2_HUMAN,sp|Q9BYJ9|YTHD1_HUMAN,sp|Q7Z739|YTHD3_HUMAN,tr|A0A087X0Q1|A0A087X0Q1_HUMAN,tr|A0A024R7W5|A0A024R7W5_HUMAN,tr|A0A087WY31|A0A087WY31_HUMAN" 6 1033.4465 1.92 95365 6758 2 1033.446884 517.7305 YTH domain-containing family protein 2 OS=Homo sapiens OX=9606 GN=YTHDF2 PE=1 SV=2 4.54 1651.9 - 562482 - - - 0.3832 - 1.651 0.485 - 217.7 1 1 0 0.0004 8 0 0 0 1.86E+07 9.71E+06 - - - 4.1352 0.9971 221125_WJC_METTL3_EV_vs_WT_F07.06759.06759.2 0.151 24-Jun R.VESVEPSENEASK[136.11].E sp|Q9H307|PININ_HUMAN 1 1411.6558 0.48 95366 6759 2 1411.656126 706.8352 Pinin OS=Homo sapiens OX=9606 GN=PNN PE=1 SV=5 4.09 1652 - 206167 - - - 0.2175 - 1.326 0.236 - 116.7 1 2 0 0.0003 13 0 0 0 1.07E+07 2.23E+07 - - - 1.5082 0.9998 221125_WJC_METTL3_EV_vs_WT_F07.06760.06760.2 2.44E-05 18-Sep K.DQLPADEC[160.03]NK.L "sp|P38646|GRP75_HUMAN,tr|A0A7I2V2S7|A0A7I2V2S7_HUMAN,tr|A0A7I2V2G2|A0A7I2V2G2_HUMAN,tr|A0A7I2V3F7|A0A7I2V3F7_HUMAN,tr|A0A7I2YQB2|A0A7I2YQB2_HUMAN,tr|D6RCD7|D6RCD7_HUMAN" 6 1188.5081 0.41 95367 6760 2 1188.50912 595.2613 "Stress-70 protein, mitochondrial OS=Homo sapiens OX=9606 GN=HSPA9 PE=1 SV=2" 4.03 1652.2 - 181206 - - - 0.8565 - 1.601 0.542 - 240.9 1 2 0 0.001 10 0 0 0 1.48E+07 3.66E+07 - - - 4.3576 0.9911 221125_WJC_METTL3_EV_vs_WT_F07.06763.06763.3 0.0731 Jul-32 K.YEK[136.11]DVADYK[136.11].S "sp|O15347|HMGB3_HUMAN,tr|E7EQU1|E7EQU1_HUMAN,tr|E7ES08|E7ES08_HUMAN" 3 1145.5576 0.001 95368 6763 3 1145.559256 382.8598 High mobility group protein B3 OS=Homo sapiens OX=9606 GN=HMGB3 PE=1 SV=4 4.56 1652.6 - 1.02E+06 - - - 1.4849 - 1.548 0.29 - 53.4 1 2 1 0.0017 9 0 0 0 0.00E+00 2.50E+07 - - - 3.0897 0.9858 221125_WJC_METTL3_EV_vs_WT_F07.06766.06766.2 0.0013 16-Sep K.YEK[136.11]DVADYK[136.11].S "sp|O15347|HMGB3_HUMAN,tr|E7EQU1|E7EQU1_HUMAN,tr|E7ES08|E7ES08_HUMAN" 3 1145.5576 0.59 95371 6766 2 1145.560995 573.7861 High mobility group protein B3 OS=Homo sapiens OX=9606 GN=HMGB3 PE=1 SV=4 4.56 1652.9 - 267668 - - - 3.0029 - 1.688 0.421 - 263.5 1 2 1 0.0034 9 0 0 0 3.29E+06 5.61E+06 - - - 3.6641 0.9989 221125_WJC_METTL3_EV_vs_WT_F07.06772.06772.2 4.76E-05 22-Jul K.SVSGTDVQEEC[160.03]R[166.11].E "sp|P49321|NASP_HUMAN,tr|E9PPR5|E9PPR5_HUMAN" 2 1375.5913 0.58 95375 6772 2 1375.596021 688.8029 Nuclear autoantigenic sperm protein OS=Homo sapiens OX=9606 GN=NASP PE=1 SV=2 4.14 1653.7 - 178198 - - - 3.4116 - 1.713 0.512 - 99.8 1 2 0 0.0047 12 0 0 0 1.60E+06 2.77E+06 - - - 4.2374 0.9991 221125_WJC_METTL3_EV_vs_WT_F07.06777.06777.2 0.000319 16-Nov K.K[136.11]SDPVVSYR[166.11].E sp|P13639|EF2_HUMAN 1 1067.573 0.26 95378 6777 2 1067.575633 534.7938 Elongation factor 2 OS=Homo sapiens OX=9606 GN=EEF2 PE=1 SV=4 8.59 1654.3 - 1.06E+06 - - - 2.4392 - 2.204 0.301 - 543.2 1 2 0 0.0026 9 0 0 0 8.82E+06 3.42E+07 - - - 3.5497 0.9998 221125_WJC_METTL3_EV_vs_WT_F07.06779.06779.2 0.000102 20-Sep R.C[160.03]EMEQQNQEYK.L "sp|Q04695|K1C17_HUMAN,sp|P02533|K1C14_HUMAN,tr|A0A3B3IS58|A0A3B3IS58_HUMAN,tr|F5GWP8|F5GWP8_HUMAN" 4 1485.5864 999 95380 6779 2 1485.589261 743.8005 "Keratin, type I cytoskeletal 17 OS=Homo sapiens OX=9606 GN=KRT17 PE=1 SV=2" 4.25 1654.5 - 288073 - - - 1.9063 - 1.966 0.606 - 230.3 1 2 0 0.0028 11 0 0 0 6.62E+08 0.00E+00 - - - 5.3448 0.9772 221125_WJC_METTL3_EV_vs_WT_F07.06793.06793.3 0.00146 16/60 K.HGK[136.11]GGGGGGGGGESGK[136.11].K sp|Q9NZ56|FMN2_HUMAN 1 1270.5985 0 95390 6793 3 1270.609361 424.5401 Formin-2 OS=Homo sapiens OX=9606 GN=FMN2 PE=1 SV=4 8.6 1656.4 - 5.28E+06 - - - 8.5283 - 3.09 0.401 - 358.9 1 2 1 0.0108 16 0 0 0 5.20E+05 2.60E+08 - - - 5.9025 0.9993 221125_WJC_METTL3_EV_vs_WT_F07.06798.06798.3 0.00724 Sep-40 K.EINTNQEALK[136.11]R[166.11].N "sp|Q93050|VPP1_HUMAN,tr|K7EN36|K7EN36_HUMAN,tr|K7EPG4|K7EPG4_HUMAN,tr|K7EM24|K7EM24_HUMAN" 4 1332.7116 0.79 95393 6798 3 1332.713118 445.2445 V-type proton ATPase 116 kDa subunit a1 OS=Homo sapiens OX=9606 GN=ATP6V0A1 PE=1 SV=3 6.24 1657 - 595098 - - - 1.103 - 1.826 0.304 - 70.4 1 2 0 0.0015 11 0 0 0 1.87E+07 2.38E+07 - - - 3.6394 1 221125_WJC_METTL3_EV_vs_WT_F07.06799.06799.2 1.38E-06 13/18 R.HMIYEESGNK.S "sp|Q8IWC1|MA7D3_HUMAN,tr|A0A0A0MRP0|A0A0A0MRP0_HUMAN" 2 1206.5339 1.06 95394 6799 2 1206.534381 604.2742 MAP7 domain-containing protein 3 OS=Homo sapiens OX=9606 GN=MAP7D3 PE=1 SV=2 5.4 1657.1 - 260758 - - - 0.3796 - 2.334 0.623 - 512.4 1 2 0 0.0005 10 0 0 0 9.30E+06 8.75E+06 - - - 6.0082 0.9962 221125_WJC_METTL3_EV_vs_WT_F07.06803.06803.2 0.00944 20-Aug K.ESQSPDTTIQR[166.11].T "sp|Q92973|TNPO1_HUMAN,tr|A0A7P0T9C0|A0A7P0T9C0_HUMAN,tr|A0A7P0TBF0|A0A7P0TBF0_HUMAN,tr|E7EW37|E7EW37_HUMAN,tr|A0A7P0T944|A0A7P0T944_HUMAN,tr|A0A7P0Z4D3|A0A7P0Z4D3_HUMAN" 6 1270.6029 0.06 95397 6803 2 1270.606717 636.3087 Transportin-1 OS=Homo sapiens OX=9606 GN=TNPO1 PE=1 SV=2 4.37 1657.5 - 966877 - - - 3.0206 - 1.364 0.363 - 92.2 1 2 0 0.0038 11 0 0 0 1.53E+06 2.70E+07 - - - 2.5607 1 221125_WJC_METTL3_EV_vs_WT_F07.06811.06811.3 1.27E-06 15/44 R.AFHNEAQVNPER[166.11].K "sp|P17987|TCPA_HUMAN,tr|F5H282|F5H282_HUMAN,tr|E7EQR6|E7EQR6_HUMAN" 3 1420.6723 0.53 95400 6811 3 1420.673331 474.5647 T-complex protein 1 subunit alpha OS=Homo sapiens OX=9606 GN=TCP1 PE=1 SV=1 5.4 1658.6 - 8.72E+06 - - - 0.7285 - 3.125 0.52 - 463.2 1 2 0 0.001 12 0 0 0 7.54E+08 1.42E+09 - - - 7.4955 1 221125_WJC_METTL3_EV_vs_WT_F07.06812.06812.3 2.99E-05 15/44 R.AFHNEAQVNPER.K "sp|P17987|TCPA_HUMAN,tr|F5H282|F5H282_HUMAN,tr|E7EQR6|E7EQR6_HUMAN" 3 1410.664 0.52 95401 6812 3 1410.665873 471.2286 T-complex protein 1 subunit alpha OS=Homo sapiens OX=9606 GN=TCP1 PE=1 SV=1 5.4 1658.6 - 4.29E+06 - - - 1.3093 - 2.533 0.515 - 453.7 1 2 0 0.0018 12 0 0 0 7.36E+08 1.42E+09 - - - 6.8574 0.9997 221125_WJC_METTL3_EV_vs_WT_F07.06816.06816.3 0.00135 Oct-32 K.FAC[160.03]PEC[160.03]PK[136.11]R[166.11].F sp|P08047|SP1_HUMAN 1 1181.5441 0.81 95405 6816 3 1181.544866 394.8553 Transcription factor Sp1 OS=Homo sapiens OX=9606 GN=SP1 PE=1 SV=3 8.06 1658.9 - 545554 - - - 0.6872 - 1.656 0.377 - 106.5 1 2 0 0.0008 9 0 0 0 2.44E+07 3.01E+07 - - - 4.2631 1 221125_WJC_METTL3_EV_vs_WT_F07.06817.06817.2 1.19E-12 15/22 R.AFHNEAQVNPER[166.11].K "sp|P17987|TCPA_HUMAN,tr|F5H282|F5H282_HUMAN,tr|E7EQR6|E7EQR6_HUMAN" 3 1420.6723 0.5 95406 6817 2 1420.672775 711.3434 T-complex protein 1 subunit alpha OS=Homo sapiens OX=9606 GN=TCP1 PE=1 SV=1 5.4 1659.1 - 528643 - - - 0.3372 - 2.903 0.685 - 730.3 1 2 0 0.0005 12 0 0 0 5.63E+07 1.12E+08 - - - 6.9044 0.9999 221125_WJC_METTL3_EV_vs_WT_F07.06818.06818.2 0.000405 13/20 R.TSNEVTVETDK[136.11].K "sp|Q9NRY5|F1142_HUMAN,tr|E7ESJ7|E7ESJ7_HUMAN" 2 1229.5867 1.12 95407 6818 2 1229.588147 615.8006 Protein FAM114A2 OS=Homo sapiens OX=9606 GN=FAM114A2 PE=1 SV=4 4.14 1659.2 - 446305 - - - 1.1963 - 2.499 0.495 - 879.9 1 2 0 0.0015 11 0 0 0 1.37E+07 1.23E+07 - - - 5.1743 0.9996 221125_WJC_METTL3_EV_vs_WT_F07.06819.06819.2 0.000191 24-Aug R.FSSSSGYGGGSSR.V sp|P35527|K1C9_HUMAN 1 1234.5214 999 95408 6819 2 1234.522851 618.268 "Keratin, type I cytoskeletal 9 OS=Homo sapiens OX=9606 GN=KRT9 PE=1 SV=3" 8.75 1659.3 - 424751 - - - 1.1397 - 1.549 0.477 - 186.4 1 2 0 0.0014 13 0 0 0 2.45E+07 0.00E+00 - - - 3.6868 0.9999 221125_WJC_METTL3_EV_vs_WT_F07.06825.06825.3 0.00164 Aug-40 R.C[160.03]EMEQQNQEYK.L "sp|Q04695|K1C17_HUMAN,sp|P02533|K1C14_HUMAN,tr|A0A3B3IS58|A0A3B3IS58_HUMAN,tr|F5GWP8|F5GWP8_HUMAN" 4 1485.5864 36.4 95412 6825 3 1485.587963 496.2028 "Keratin, type I cytoskeletal 17 OS=Homo sapiens OX=9606 GN=KRT17 PE=1 SV=2" 4.25 1660.1 - 1.58E+06 - - - 1.0326 - 1.573 0.5 - 110.9 1 2 0 0.0015 11 0 0 0 4.36E+07 1.20E+06 - - - 5.4009 0.9963 221125_WJC_METTL3_EV_vs_WT_F07.06826.06826.2 0.00304 20-Sep R.EEK[136.11]DNIQPTTE.- sp|Q9Y2W1|TR150_HUMAN 1 1310.6081 2.97 95413 6826 2 1310.608668 656.3113 Thyroid hormone receptor-associated protein 3 OS=Homo sapiens OX=9606 GN=THRAP3 PE=1 SV=2 4.24 1660.2 - 817506 - - - 0.4029 - 1.634 0.426 - 276.5 1 2 1 0.0005 11 0 0 0 4.91E+08 1.65E+08 - - - 3.5156 0.9999 221125_WJC_METTL3_EV_vs_WT_F07.06827.06827.3 1.87E-07 Nov-36 R.SHEGETAYIR[166.11].V "sp|Q07955|SRSF1_HUMAN,tr|J3KTL2|J3KTL2_HUMAN,tr|J3KSR8|J3KSR8_HUMAN" 3 1171.5497 1.15 95414 6827 3 1171.550513 391.5239 Serine\arginine-rich splicing factor 1 OS=Homo sapiens OX=9606 GN=SRSF1 PE=1 SV=2 5.38 1660.3 - 727381 - - - 0.676 - 2.087 0.456 - 276.3 1 2 0 0.0008 10 0 0 0 9.59E+07 8.37E+07 - - - 5.7724 1 221125_WJC_METTL3_EV_vs_WT_F07.06828.06828.2 1.52E-07 22-Nov R.AFHNEAQVNPER.K "sp|P17987|TCPA_HUMAN,tr|F5H282|F5H282_HUMAN,tr|E7EQR6|E7EQR6_HUMAN" 3 1410.664 0.51 95415 6828 2 1410.663184 706.3393 T-complex protein 1 subunit alpha OS=Homo sapiens OX=9606 GN=TCP1 PE=1 SV=1 5.4 1660.4 - 546752 - - - -0.5969 - 2.34 0.62 - 354.5 1 2 0 -0.0008 12 0 0 0 5.67E+07 1.12E+08 - - - 5.8569 0.9998 221125_WJC_METTL3_EV_vs_WT_F07.06831.06831.2 5.69E-07 22-Oct R.STTQVADSGYQR[166.11].G sp|Q96A65|EXOC4_HUMAN 1 1321.6138 31.6 95417 6831 2 1321.611435 661.8142 Exocyst complex component 4 OS=Homo sapiens OX=9606 GN=EXOC4 PE=1 SV=1 5.55 1660.8 - 210292 - - - -1.7728 - 2.055 0.55 - 354.9 1 2 0 -0.0023 12 0 0 0 8.26E+07 2.61E+06 - - - 4.9977 0.9997 221125_WJC_METTL3_EV_vs_WT_F07.06836.06836.2 0.000258 18-Oct K.TTNYSTVPQK.Q "sp|Q6PJT7|ZC3HE_HUMAN,tr|G3V256|G3V256_HUMAN,tr|G3V5I6|G3V5I6_HUMAN,tr|H0YJA2|H0YJA2_HUMAN,tr|A0A087WTC9|A0A087WTC9_HUMAN" 5 1137.5666 1.39 95420 6836 2 1137.566996 569.7906 Zinc finger CCCH domain-containing protein 14 OS=Homo sapiens OX=9606 GN=ZC3H14 PE=1 SV=1 8.26 1661.4 - 862182 - - - 0.3455 - 1.672 0.423 - 308.2 1 2 0 0.0004 10 0 0 0 7.88E+07 5.67E+07 - - - 3.5999 0.9734 221125_WJC_METTL3_EV_vs_WT_F07.06838.06838.2 0.0562 26-Jun K.SDPPEGSEEAAEPR.M "sp|Q9ULV3|CIZ1_HUMAN,tr|Q5SYW2|Q5SYW2_HUMAN,tr|F5H2X7|F5H2X7_HUMAN,tr|H0Y5D5|H0Y5D5_HUMAN,tr|A0A494C0L7|A0A494C0L7_HUMAN,tr|Q9BTG3|Q9BTG3_HUMAN,tr|F6VD24|F6VD24_HUMAN" 7 1469.627 21.31 95422 6838 2 1469.632925 735.8208 Cip1-interacting zinc finger protein OS=Homo sapiens OX=9606 GN=CIZ1 PE=1 SV=2 3.91 1661.7 - 202245 - - - 4.0105 - 0.992 0.339 - 54.1 1 2 0 0.0059 14 0 0 0 1.14E+07 5.33E+05 - - - 1.5228 0.9997 221125_WJC_METTL3_EV_vs_WT_F07.06845.06845.2 4.58E-05 18-Sep R.SHEGETAYIR[166.11].V "sp|Q07955|SRSF1_HUMAN,tr|J3KTL2|J3KTL2_HUMAN,tr|J3KSR8|J3KSR8_HUMAN" 3 1171.5497 1.2 95426 6845 2 1171.547268 586.7821 Serine\arginine-rich splicing factor 1 OS=Homo sapiens OX=9606 GN=SRSF1 PE=1 SV=2 5.38 1662.5 - 741259 - - - -2.0938 - 1.713 0.536 - 277.1 1 2 0 -0.0025 10 0 0 0 3.47E+07 2.89E+07 - - - 4.5015 1 221125_WJC_METTL3_EV_vs_WT_F07.06847.06847.2 6.72E-06 15/18 K.KDVDAAYMNK.V "sp|P48668|K2C6C_HUMAN,sp|P04259|K2C6B_HUMAN,sp|P13647|K2C5_HUMAN,sp|Q14CN4|K2C72_HUMAN,sp|O95678|K2C75_HUMAN,sp|P02538|K2C6A_HUMAN,tr|F8W0C6|F8W0C6_HUMAN,tr|H0YIN9|H0YIN9_HUMAN" 8 1153.5438 18.53 95428 6847 2 1153.540455 577.7792 "Keratin, type II cytoskeletal 6C OS=Homo sapiens OX=9606 GN=KRT6C PE=1 SV=3" 5.96 1662.8 - 405064 - - - -2.8642 - 2.601 0.567 - 800.1 1 2 0 -0.0033 10 0 0 0 1.48E+08 7.99E+06 - - - 5.896 0.9998 221125_WJC_METTL3_EV_vs_WT_F07.06851.06851.2 0.000127 18-Sep R.SHEGETAYIR.V "sp|Q07955|SRSF1_HUMAN,tr|J3KTL2|J3KTL2_HUMAN,tr|J3KSR8|J3KSR8_HUMAN" 3 1161.5415 1.2 95431 6851 2 1161.541611 581.778 Serine\arginine-rich splicing factor 1 OS=Homo sapiens OX=9606 GN=SRSF1 PE=1 SV=2 5.38 1663.3 - 937988 - - - 0.1377 - 1.802 0.517 - 259.7 1 2 0 0.0002 10 0 0 0 3.46E+07 2.87E+07 - - - 4.5033 0.9999 221125_WJC_METTL3_EV_vs_WT_F07.06854.06854.3 0.0183 Dec-44 R.LTEPQHGLGSQR.D "sp|Q13586|STIM1_HUMAN,tr|G0XQ39|G0XQ39_HUMAN,tr|E9PNJ4|E9PNJ4_HUMAN,tr|H0YDB2|H0YDB2_HUMAN" 4 1321.6739 1.2 95432 6854 3 1321.673201 441.5652 Stromal interaction molecule 1 OS=Homo sapiens OX=9606 GN=STIM1 PE=1 SV=3 6.75 1663.6 - 797261 - - - -0.5001 - 2.197 0.382 - 209.8 1 2 0 -0.0007 12 0 0 0 1.43E+07 1.19E+07 - - - 4.9804 0.9507 221125_WJC_METTL3_EV_vs_WT_F07.06855.06855.3 0.632 Aug-44 R.LQAGEETASHYR[166.11].M sp|Q9UBB6|NCDN_HUMAN 1 1370.6454 0.58 95433 6855 3 1370.646394 457.8891 Neurochondrin OS=Homo sapiens OX=9606 GN=NCDN PE=1 SV=1 5.4 1663.6 - 1.68E+06 - - - 0.7165 - 1.268 0.162 - 78 2 2 0 0.001 12 0 0 0 8.12E+06 1.39E+07 - - - 0.8647 0.9986 221125_WJC_METTL3_EV_vs_WT_F07.06856.06856.3 0.561 Oct-44 R.LTEPQHGLGSQR[166.11].D "sp|Q13586|STIM1_HUMAN,tr|G0XQ39|G0XQ39_HUMAN,tr|E9PNJ4|E9PNJ4_HUMAN,tr|H0YDB2|H0YDB2_HUMAN" 4 1331.6821 1 95434 6856 3 1331.681146 444.9013 Stromal interaction molecule 1 OS=Homo sapiens OX=9606 GN=STIM1 PE=1 SV=3 6.75 1663.8 - 604060 - - - -0.7404 - 2.11 0.223 - 110.2 1 2 0 -0.001 12 0 0 0 2.92E+07 2.92E+07 - - - 3.0957 0.9913 221125_WJC_METTL3_EV_vs_WT_F07.06857.06857.2 2.61E-05 22-Nov R.TTVDSVEGNASK.L "sp|Q3V6T2|GRDN_HUMAN,tr|A0A087WXD9|A0A087WXD9_HUMAN,tr|A0A2R8YG52|A0A2R8YG52_HUMAN,tr|A0A2U3TZV9|A0A2U3TZV9_HUMAN,tr|A0A2R8YG73|A0A2R8YG73_HUMAN,tr|A0A2R8YGU1|A0A2R8YGU1_HUMAN,tr|A0A2R8Y7D9|A0A2R8Y7D9_HUMAN,tr|A0A2R8Y6B2|A0A2R8Y6B2_HUMAN,tr|A0A2R8Y4X4|A0A2R8Y4X4_HUMAN,tr|A0A2R8Y4W8|A0A2R8Y4W8_HUMAN,tr|A0A2R8Y7B1|A0A2R8Y7B1_HUMAN" 11 1206.5728 4.6 95435 6857 2 1206.581455 604.2937 Girdin OS=Homo sapiens OX=9606 GN=CCDC88A PE=1 SV=2 4.37 1663.9 - 311890 - - - 7.1641 - 2.256 0.509 - 383.1 1 2 0 0.0086 12 0 0 0 8.69E+06 1.89E+06 - - - 4.9385 0.9877 221125_WJC_METTL3_EV_vs_WT_F07.06868.06868.2 0.561 22-Jun K.RIANSAGYVGDR.F "sp|Q6W2J9|BCOR_HUMAN,tr|H7BZ37|H7BZ37_HUMAN,tr|A1A564|A1A564_HUMAN,tr|H7C2V9|H7C2V9_HUMAN,tr|H7BYY2|H7BYY2_HUMAN,tr|H7C231|H7C231_HUMAN" 6 1277.6476 2.05 95442 6868 2 1277.647159 639.8311 BCL-6 corepressor OS=Homo sapiens OX=9606 GN=BCOR PE=1 SV=1 8.75 1665.3 - 418289 - - - -0.382 - 1.156 0.144 - 37.4 1 2 0 -0.0005 12 0 0 0 4.77E+06 2.33E+06 - - - 0.4859 0.9998 221125_WJC_METTL3_EV_vs_WT_F07.06869.06869.2 0.00147 24-Oct K.VQAQAEQGQQELK.N sp|Q9BW19|KIFC1_HUMAN 1 1455.7318 0.84 95443 6869 2 1455.731595 728.8732 Kinesin-like protein KIFC1 OS=Homo sapiens OX=9606 GN=KIFC1 PE=1 SV=2 4.53 1665.4 - 242778 - - - -0.1209 - 2.166 0.462 - 308.2 1 2 0 -0.0002 13 0 0 0 3.01E+06 3.59E+06 - - - 4.4369 1 221125_WJC_METTL3_EV_vs_WT_F07.06871.06871.3 4.51E-06 14/44 K.R[166.11]IANSAGYVGDR[166.11].F "sp|Q6W2J9|BCOR_HUMAN,tr|H7BZ37|H7BZ37_HUMAN,tr|A1A564|A1A564_HUMAN,tr|H7C2V9|H7C2V9_HUMAN,tr|H7BYY2|H7BYY2_HUMAN,tr|H7C231|H7C231_HUMAN" 6 1297.6642 1.92 95445 6871 3 1297.664754 433.562 BCL-6 corepressor OS=Homo sapiens OX=9606 GN=BCOR PE=1 SV=1 8.75 1665.7 - 734267 - - - 0.4369 - 2.703 0.493 - 261.2 1 2 0 0.0006 12 0 0 0 1.50E+07 7.79E+06 - - - 6.7925 0.9904 221125_WJC_METTL3_EV_vs_WT_F07.06872.06872.2 0.894 20-Jul R.R[166.11]LASTSDIEEK[136.11].E "sp|O14974|MYPT1_HUMAN,tr|F8VZN8|F8VZN8_HUMAN,tr|H0YHI8|H0YHI8_HUMAN,tr|H0YIS4|H0YIS4_HUMAN,tr|A0A3B3ISH4|A0A3B3ISH4_HUMAN" 5 1265.6582 0.7 95446 6872 2 1265.659006 633.8364 Protein phosphatase 1 regulatory subunit 12A OS=Homo sapiens OX=9606 GN=PPP1R12A PE=1 SV=1 4.68 1665.8 - 361123 - - - 0.625 - 1.689 0.055 - 154.9 2 2 0 0.0008 11 0 0 0 3.01E+06 4.31E+06 - - - 0.7304 0.9532 221125_WJC_METTL3_EV_vs_WT_F07.06874.06874.2 0.162 16-May R.SNQPYYNSR.G "sp|Q14444|CAPR1_HUMAN,tr|G3V153|G3V153_HUMAN" 2 1127.4996 4.34 95448 6874 2 1127.502364 564.7571 Caprin-1 OS=Homo sapiens OX=9606 GN=CAPRIN1 PE=1 SV=2 8.31 1666 - 175850 - - - 2.4639 - 1 0.175 - 69.4 1 2 0 0.0028 9 0 0 0 2.91E+06 6.70E+05 - - - 0.3327 1 221125_WJC_METTL3_EV_vs_WT_F07.06877.06877.3 6.99E-05 Nov-36 K.KDVDAAYMNK.V "sp|P48668|K2C6C_HUMAN,sp|P04259|K2C6B_HUMAN,sp|P13647|K2C5_HUMAN,sp|Q14CN4|K2C72_HUMAN,sp|O95678|K2C75_HUMAN,sp|P02538|K2C6A_HUMAN,tr|F8W0C6|F8W0C6_HUMAN,tr|H0YIN9|H0YIN9_HUMAN" 8 1153.5438 96.13 95449 6877 3 1153.543502 385.5219 "Keratin, type II cytoskeletal 6C OS=Homo sapiens OX=9606 GN=KRT6C PE=1 SV=3" 5.96 1666.4 - 7.46E+06 - - - -0.2228 - 2.166 0.52 - 251.2 1 2 0 -0.0003 10 0 0 0 2.21E+08 2.30E+06 - - - 6.5946 0.9999 221125_WJC_METTL3_EV_vs_WT_F07.06883.06883.3 0.0119 13/52 R.MITTSGPTSEKPTR.S "sp|O43318|M3K7_HUMAN,tr|Q9UG54|Q9UG54_HUMAN" 2 1504.7555 1.78 95455 6883 3 1504.755307 502.5925 Mitogen-activated protein kinase kinase kinase 7 OS=Homo sapiens OX=9606 GN=MAP3K7 PE=1 SV=1 8.5 1667 - 370625 - - - -0.1568 - 2.822 0.386 - 189.9 1 2 0 -0.0002 14 0 0 0 1.96E+07 1.10E+07 - - - 5.6005 0.9992 221125_WJC_METTL3_EV_vs_WT_F07.06884.06884.2 0.000128 18-Aug K.DSVADPHNLK[136.11].L "sp|Q6P2I3|FAH2B_HUMAN,sp|Q96GK7|FAH2A_HUMAN" 2 1102.5498 2.29 95456 6884 2 1102.552305 552.2822 Fumarylacetoacetate hydrolase domain-containing protein 2B OS=Homo sapiens OX=9606 GN=FAHD2B PE=1 SV=1 5.21 1667.1 - 341431 - - - 2.2384 - 1.538 0.447 - 231.3 1 2 0 0.0025 10 0 0 0 4.55E+07 1.99E+07 - - - 3.5434 0.9998 221125_WJC_METTL3_EV_vs_WT_F07.06887.06887.2 0.000228 22-Nov R.EVFTSSSSSSSR.Q sp|P08779|K1C16_HUMAN 1 1259.563 735.77 95458 6887 2 1259.562871 630.7888 "Keratin, type I cytoskeletal 16 OS=Homo sapiens OX=9606 GN=KRT16 PE=1 SV=4" 6.1 1667.5 - 1.37E+07 - - - -0.0818 - 2.293 0.373 - 415.2 1 2 0 -0.0001 12 0 0 0 2.78E+09 3.78E+06 - - - 3.9795 0.9413 221125_WJC_METTL3_EV_vs_WT_F07.06890.06890.3 0.111 Sep-44 K.TLEEQGVAHNVK.A "sp|Q9Y5A7|NUB1_HUMAN,tr|H3BM74|H3BM74_HUMAN,tr|C9JRT6|C9JRT6_HUMAN,tr|H3BM14|H3BM14_HUMAN,tr|F8WDB6|F8WDB6_HUMAN" 5 1323.6783 0.95 95460 6890 3 1323.676944 442.2334 NEDD8 ultimate buster 1 OS=Homo sapiens OX=9606 GN=NUB1 PE=1 SV=2 5.37 1667.8 - 863803 - - - -1.0086 - 1.446 0.108 - 88.3 1 2 0 -0.0013 12 0 0 0 3.00E+07 3.15E+07 - - - 0.766 0.9998 221125_WJC_METTL3_EV_vs_WT_F07.06891.06891.2 0.000324 14/26 K.K[136.11]GPGEVAGTVTGQK[136.11].R "sp|Q86U44|MTA70_HUMAN,tr|F5H6D8|F5H6D8_HUMAN,tr|H0YFV6|H0YFV6_HUMAN,tr|B4DTN4|B4DTN4_HUMAN" 4 1343.738 0.001 95461 6891 2 1343.736438 672.8763 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 8.59 1667.8 - 3.34E+06 - - - -1.1468 - 2.321 0.472 - 436.4 1 2 0 -0.0015 14 0 0 0 0.00E+00 1.76E+08 - - - 4.6397 0.9986 221125_WJC_METTL3_EV_vs_WT_F07.06894.06894.3 0.113 Oct-44 K.EAVGGQAEDHLK[136.11].L "sp|Q8IWC1|MA7D3_HUMAN,tr|A0A0A0MRP0|A0A0A0MRP0_HUMAN" 2 1260.619 2.81 95464 6894 3 1260.617397 421.2136 MAP7 domain-containing protein 3 OS=Homo sapiens OX=9606 GN=MAP7D3 PE=1 SV=2 4.65 1668.1 - 688538 - - - -1.2557 - 1.721 0.281 - 158.8 1 2 0 -0.0016 12 0 0 0 1.78E+08 6.33E+07 - - - 3.1773 0.9999 221125_WJC_METTL3_EV_vs_WT_F07.06898.06898.3 0.0139 15/40 K.IYEDGDDDMK[136.11]R[166.11].T sp|Q9HB71|CYBP_HUMAN 1 1373.5888 0.1 95466 6898 3 1373.586746 458.8702 Calcyclin-binding protein OS=Homo sapiens OX=9606 GN=CACYBP PE=1 SV=2 4.04 1668.6 - 535101 - - - -1.5063 - 1.917 0.47 - 187.6 1 2 0 -0.0021 11 0 0 0 2.42E+06 2.32E+07 - - - 5.6282 1 221125_WJC_METTL3_EV_vs_WT_F07.06900.06900.2 3.52E-08 18-Dec R.YDSYESC[160.03]DSR[166.11].A "sp|Q9ULX6|AKP8L_HUMAN,tr|M0QYT7|M0QYT7_HUMAN,tr|A0A7P0T9N5|A0A7P0T9N5_HUMAN,tr|A0A7P0TAD3|A0A7P0TAD3_HUMAN,tr|V9GZ50|V9GZ50_HUMAN,tr|A0A7P0TBP0|A0A7P0TBP0_HUMAN,tr|M0R1Y5|M0R1Y5_HUMAN,tr|A0A7P0TAJ5|A0A7P0TAJ5_HUMAN,tr|A0A7P0TAE3|A0A7P0TAE3_HUMAN,tr|M0R010|M0R010_HUMAN,tr|A0A7P0T847|A0A7P0T847_HUMAN" 11 1290.4698 0.98 95468 6900 2 1290.475032 646.2422 A-kinase anchor protein 8-like OS=Homo sapiens OX=9606 GN=AKAP8L PE=1 SV=4 4.03 1668.9 - 302199 - - - 4.0419 - 2.328 0.78 - 470.3 1 2 0 0.0052 10 0 0 0 1.47E+07 1.49E+07 - - - 7.1591 0.9989 221125_WJC_METTL3_EV_vs_WT_F07.06902.06902.2 0.0132 20-Jun R.NPPPNSDPNLR.R sp|Q96I24|FUBP3_HUMAN 1 1219.5945 44.82 95470 6902 2 1219.595755 610.8046 Far upstream element-binding protein 3 OS=Homo sapiens OX=9606 GN=FUBP3 PE=1 SV=2 5.84 1669.1 - 168322 - - - 0.9889 - 1.361 0.359 - 57.3 1 2 0 0.0012 11 0 0 0 6.21E+06 1.39E+05 - - - 2.526 0.9999 221125_WJC_METTL3_EV_vs_WT_F07.06903.06903.2 4.69E-05 18-Aug R.YDSYESC[160.03]DSR.A "sp|Q9ULX6|AKP8L_HUMAN,tr|M0QYT7|M0QYT7_HUMAN,tr|A0A7P0T9N5|A0A7P0T9N5_HUMAN,tr|A0A7P0TAD3|A0A7P0TAD3_HUMAN,tr|V9GZ50|V9GZ50_HUMAN,tr|A0A7P0TBP0|A0A7P0TBP0_HUMAN,tr|M0R1Y5|M0R1Y5_HUMAN,tr|A0A7P0TAJ5|A0A7P0TAJ5_HUMAN,tr|A0A7P0TAE3|A0A7P0TAE3_HUMAN,tr|M0R010|M0R010_HUMAN,tr|A0A7P0T847|A0A7P0T847_HUMAN" 11 1280.4615 0.98 95471 6903 2 1280.461545 641.238 A-kinase anchor protein 8-like OS=Homo sapiens OX=9606 GN=AKAP8L PE=1 SV=4 4.03 1669.3 - 144316 - - - -0.0008 - 1.617 0.629 - 153.6 1 2 0 0 10 0 0 0 1.47E+07 1.49E+07 - - - 5.0282 0.9997 221125_WJC_METTL3_EV_vs_WT_F07.06908.06908.2 5.90E-06 24-Nov R.VVTSEDQVQEGTK[136.11].V "sp|Q8WWK9|CKAP2_HUMAN,tr|C9J7Y4|C9J7Y4_HUMAN" 2 1426.7031 0.59 95473 6908 2 1426.699114 714.3588 Cytoskeleton-associated protein 2 OS=Homo sapiens OX=9606 GN=CKAP2 PE=1 SV=1 4.14 1670 - 420150 - - - -2.796 - 2.417 0.564 - 305.4 1 2 0 -0.004 13 0 0 0 7.03E+06 1.19E+07 - - - 5.4705 0.9968 221125_WJC_METTL3_EV_vs_WT_F07.06912.06912.2 0.00545 14-Sep R.TDRLEVC[160.03]R.E "sp|Q9NR56|MBNL1_HUMAN,tr|H7C4T5|H7C4T5_HUMAN,tr|Q86VM6|Q86VM6_HUMAN,tr|H7C4Y1|H7C4Y1_HUMAN,tr|A0A0A0MQX8|A0A0A0MQX8_HUMAN,tr|C9JCX1|C9JCX1_HUMAN,tr|C9JP00|C9JP00_HUMAN" 7 1047.5131 1.81 95475 6912 2 1047.512753 524.7638 Muscleblind-like protein 1 OS=Homo sapiens OX=9606 GN=MBNL1 PE=1 SV=2 5.73 1670.5 - 838011 - - - -0.358 - 1.717 0.401 - 171.9 1 2 1 -0.0004 8 0 0 0 1.44E+07 7.91E+06 - - - 3.633 0.9999 221125_WJC_METTL3_EV_vs_WT_F07.06919.06919.3 1.11E-05 Dec-36 R.NTEEEGLK[136.11]YK[136.11].S "sp|Q9NYF8|BCLF1_HUMAN,tr|E9PKI6|E9PKI6_HUMAN,tr|A0A1W2PQ43|A0A1W2PQ43_HUMAN,tr|E9PK91|E9PK91_HUMAN,tr|E9PK09|E9PK09_HUMAN,tr|E9PQN2|E9PQN2_HUMAN" 6 1225.6161 2.16 95480 6919 3 1225.615529 409.546 Bcl-2-associated transcription factor 1 OS=Homo sapiens OX=9606 GN=BCLAF1 PE=1 SV=2 4.79 1671.4 - 1.04E+07 - - - -0.4928 - 2.063 0.523 - 213.4 1 2 1 -0.0006 10 0 0 0 2.39E+09 1.11E+09 - - - 6.4856 0.9943 221125_WJC_METTL3_EV_vs_WT_F07.06924.06924.2 0.221 16-Nov R.LRSEIDNVK.K sp|P04264|K2C1_HUMAN 1 1072.5877 24.58 95483 6924 2 1072.587321 537.3011 "Keratin, type II cytoskeletal 1 OS=Homo sapiens OX=9606 GN=KRT1 PE=1 SV=6" 6.07 1671.9 - 1.89E+06 - - - -0.3282 - 1.916 0.282 - 507 1 2 1 -0.0004 9 0 0 0 4.40E+07 1.79E+06 - - - 3.0049 0.9997 221125_WJC_METTL3_EV_vs_WT_F07.06925.06925.2 0.000218 18-Oct K.DQESFGSASK.S "sp|Q9NZM3|ITSN2_HUMAN,tr|A0A087WVF7|A0A087WVF7_HUMAN" 2 1054.4567 4.4 95484 6925 2 1054.457102 528.2356 Intersectin-2 OS=Homo sapiens OX=9606 GN=ITSN2 PE=1 SV=3 4.37 1672 - 760664 - - - 0.3642 - 1.721 0.395 - 213.3 1 2 0 0.0004 10 0 0 0 1.53E+07 3.47E+06 - - - 3.4738 0.9993 221125_WJC_METTL3_EV_vs_WT_F07.06934.06934.3 0.00175 Nov-36 R.NTEEEGLKYK.S "sp|Q9NYF8|BCLF1_HUMAN,tr|E9PKI6|E9PKI6_HUMAN,tr|A0A1W2PQ43|A0A1W2PQ43_HUMAN,tr|E9PK91|E9PK91_HUMAN,tr|E9PK09|E9PK09_HUMAN,tr|E9PQN2|E9PQN2_HUMAN" 6 1209.5877 2.16 95490 6934 3 1209.587392 404.2032 Bcl-2-associated transcription factor 1 OS=Homo sapiens OX=9606 GN=BCLAF1 PE=1 SV=2 4.79 1672.9 - 3.92E+07 - - - -0.2819 - 2.029 0.376 - 173.5 1 2 1 -0.0003 10 0 0 0 2.39E+09 1.11E+09 - - - 4.7983 0.9987 221125_WJC_METTL3_EV_vs_WT_F07.06935.06935.3 0.0138 Aug-52 K.K[136.11]GPGEVAGTVTGQK[136.11].R "sp|Q86U44|MTA70_HUMAN,tr|F5H6D8|F5H6D8_HUMAN,tr|H0YFV6|H0YFV6_HUMAN,tr|B4DTN4|B4DTN4_HUMAN" 4 1343.738 0.01 95491 6935 3 1343.739139 448.9199 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 8.59 1672.9 - 1.24E+06 - - - 0.8633 - 1.862 0.268 - 100.2 1 2 0 0.0012 14 0 0 0 5.01E+06 4.81E+08 - - - 3.1797 0.9995 221125_WJC_METTL3_EV_vs_WT_F07.06941.06941.2 0.00355 16-May R.ESNC[160.03]YDPER.V "sp|Q00610|CLH1_HUMAN,tr|A0A087WVQ6|A0A087WVQ6_HUMAN" 2 1168.4455 0.93 95495 6941 2 1168.444672 585.23 Clathrin heavy chain 1 OS=Homo sapiens OX=9606 GN=CLTC PE=1 SV=5 4.14 1673.7 - 384855 - - - -0.7103 - 1.186 0.484 - 91.5 1 2 0 -0.0008 9 0 0 0 3.16E+07 3.42E+07 - - - 3.1091 1 221125_WJC_METTL3_EV_vs_WT_F07.06942.06942.3 1.25E-05 Dec-36 R.SHEGETAYIR.V "sp|Q07955|SRSF1_HUMAN,tr|J3KTL2|J3KTL2_HUMAN,tr|J3KSR8|J3KSR8_HUMAN" 3 1161.5415 1.13 95496 6942 3 1161.540007 388.1878 Serine\arginine-rich splicing factor 1 OS=Homo sapiens OX=9606 GN=SRSF1 PE=1 SV=2 5.38 1673.8 - 712520 - - - -1.2432 - 2.276 0.478 - 340.8 1 2 0 -0.0014 10 0 0 0 9.39E+07 8.33E+07 - - - 6.2707 0.9988 221125_WJC_METTL3_EV_vs_WT_F07.06946.06946.2 5.70E-06 18-Nov R.NTEEEGLK[136.11]YK[136.11].S "sp|Q9NYF8|BCLF1_HUMAN,tr|E9PKI6|E9PKI6_HUMAN,tr|A0A1W2PQ43|A0A1W2PQ43_HUMAN,tr|E9PK91|E9PK91_HUMAN,tr|E9PK09|E9PK09_HUMAN,tr|E9PQN2|E9PQN2_HUMAN" 6 1225.6161 2.21 95499 6946 2 1225.615637 613.8153 Bcl-2-associated transcription factor 1 OS=Homo sapiens OX=9606 GN=BCLAF1 PE=1 SV=2 4.79 1674.3 - 1.05E+07 - - - -0.4047 - 2.232 0.529 - 488.4 1 2 1 -0.0005 10 0 0 0 6.65E+08 3.01E+08 - - - 5.1892 0.9999 221125_WJC_METTL3_EV_vs_WT_F07.06948.06948.3 0.00049 Oct-40 K.VEEHEETFEEK.L "sp|P07197|NFM_HUMAN,tr|E7ESP9|E7ESP9_HUMAN,tr|E7EMV2|E7EMV2_HUMAN" 3 1404.6045 1.7 95500 6948 3 1404.603911 469.2088 Neurofilament medium polypeptide OS=Homo sapiens OX=9606 GN=NEFM PE=1 SV=3 4.2 1674.5 - 4.25E+06 - - - -0.4229 - 2.028 0.457 - 198.2 1 2 0 -0.0006 11 0 0 0 1.25E+08 7.39E+07 - - - 5.6435 0.9757 221125_WJC_METTL3_EV_vs_WT_F07.06949.06949.2 0.00708 16-Aug R.K[136.11]HAASDVDL.E "sp|Q86U44|MTA70_HUMAN,tr|F5H6D8|F5H6D8_HUMAN,tr|H0YFV6|H0YFV6_HUMAN,tr|B4DTN4|B4DTN4_HUMAN" 4 962.4913 2.45 95501 6949 2 962.490401 482.2529 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 5.21 1674.6 - 629521 - - - -0.8925 - 1.765 0.363 - 239.9 1 1 0 -0.0009 9 0 0 0 4.38E+07 1.79E+07 - - - 3.3655 0.9999 221125_WJC_METTL3_EV_vs_WT_F07.06953.06953.2 6.46E-05 16-Aug R.ESNC[160.03]YDPER[166.11].V "sp|Q00610|CLH1_HUMAN,tr|A0A087WVQ6|A0A087WVQ6_HUMAN" 2 1178.4538 0.93 95505 6953 2 1178.453772 590.2342 Clathrin heavy chain 1 OS=Homo sapiens OX=9606 GN=CLTC PE=1 SV=5 4.14 1675 - 323812 - - - 0 - 1.663 0.611 - 224.1 1 2 0 0 9 0 0 0 3.16E+07 3.42E+07 - - - 5.0253 0.9997 221125_WJC_METTL3_EV_vs_WT_F07.06957.06957.3 0.0779 Dec-48 K.EADLAAQEEAAKK.- sp|Q9Y3B7|RM11_HUMAN 1 1372.6834 1.05 95507 6957 3 1372.682801 458.5684 "39S ribosomal protein L11, mitochondrial OS=Homo sapiens OX=9606 GN=MRPL11 PE=1 SV=1" 4.41 1675.5 - 1.75E+06 - - - -0.4539 - 2.305 0.308 - 186.7 1 2 0 -0.0006 13 0 0 0 4.23E+07 4.05E+07 - - - 4.2379 0.9992 221125_WJC_METTL3_EV_vs_WT_F07.06963.06963.3 0.00364 Sep-36 R.TLSKDDVNYK.M "sp|P48651|PTSS1_HUMAN,tr|J3KNR6|J3KNR6_HUMAN" 2 1181.5928 0.7 95513 6963 3 1181.593252 394.8715 Phosphatidylserine synthase 1 OS=Homo sapiens OX=9606 GN=PTDSS1 PE=1 SV=1 5.63 1676.2 - 626948 - - - 0.3673 - 1.881 0.382 - 97 1 2 1 0.0004 10 0 0 0 1.23E+07 1.77E+07 - - - 4.6439 0.9979 221125_WJC_METTL3_EV_vs_WT_F07.06967.06967.2 2.40E-05 18-Dec R.NTEEEGLKYK.S "sp|Q9NYF8|BCLF1_HUMAN,tr|E9PKI6|E9PKI6_HUMAN,tr|A0A1W2PQ43|A0A1W2PQ43_HUMAN,tr|E9PK91|E9PK91_HUMAN,tr|E9PK09|E9PK09_HUMAN,tr|E9PQN2|E9PQN2_HUMAN" 6 1209.5877 2.21 95516 6967 2 1209.586684 605.8011 Bcl-2-associated transcription factor 1 OS=Homo sapiens OX=9606 GN=BCLAF1 PE=1 SV=2 4.79 1676.6 - 3.40E+07 - - - -0.8672 - 2.386 0.389 - 691.8 1 2 1 -0.001 10 0 0 0 6.65E+08 3.01E+08 - - - 4.3412 1 221125_WJC_METTL3_EV_vs_WT_F07.06968.06968.3 7.47E-06 Nov-36 K.THEAQIQEMR[166.11].Q sp|P35579|MYH9_HUMAN 1 1251.5905 0.7 95517 6968 3 1251.588523 418.2041 Myosin-9 OS=Homo sapiens OX=9606 GN=MYH9 PE=1 SV=4 5.37 1676.7 - 8.56E+06 - - - -1.6115 - 2.314 0.55 - 389.7 1 2 0 -0.002 10 0 0 0 1.35E+08 1.94E+08 - - - 7.1216 0.9998 221125_WJC_METTL3_EV_vs_WT_F07.06969.06969.2 0.00735 16-Oct R.SQESGYYDR.M "sp|P43243|MATR3_HUMAN,tr|A8MXP9|A8MXP9_HUMAN,tr|D6R991|D6R991_HUMAN,tr|A0A0R4J2E8|A0A0R4J2E8_HUMAN,tr|D6REM6|D6REM6_HUMAN" 5 1103.452 1.3 95518 6969 2 1103.451065 552.7333 Matrin-3 OS=Homo sapiens OX=9606 GN=MATR3 PE=1 SV=2 4.37 1676.8 - 1.88E+06 - - - -0.8174 - 1.914 0.44 - 517.7 1 2 0 -0.0009 9 0 0 0 5.98E+07 4.59E+07 - - - 4.1687 0.9922 221125_WJC_METTL3_EV_vs_WT_F07.06970.06970.2 0.106 16-Aug R.SNLPDNLKK.L "sp|Q14204|DYHC1_HUMAN,tr|A0A7P0T8N2|A0A7P0T8N2_HUMAN,tr|A0A7P0T9C4|A0A7P0T9C4_HUMAN,tr|A0A7P0TBJ7|A0A7P0TBJ7_HUMAN,tr|A0A804HHY6|A0A804HHY6_HUMAN,tr|A0A7P0T9K2|A0A7P0T9K2_HUMAN,tr|A0A7P0TB64|A0A7P0TB64_HUMAN,tr|A0A2R8Y706|A0A2R8Y706_HUMAN,tr|A0A7P0T916|A0A7P0T916_HUMAN,tr|A0A7P0TB75|A0A7P0TB75_HUMAN,tr|A0A7P0T8W5|A0A7P0T8W5_HUMAN,tr|A0A7P0T9S3|A0A7P0T9S3_HUMAN,tr|A0A7P0TAF3|A0A7P0TAF3_HUMAN,tr|A0A7P0T9F1|A0A7P0T9F1_HUMAN,tr|A0A7P0TAW9|A0A7P0TAW9_HUMAN,tr|A0A2R8YGC7|A0A2R8YGC7_HUMAN,tr|A0A7P0TA13|A0A7P0TA13_HUMAN,tr|A0A7P0T934|A0A7P0T934_HUMAN,tr|A0A7P0TAV5|A0A7P0TAV5_HUMAN,tr|A0A7P0T7V5|A0A7P0T7V5_HUMAN,tr|A0A7P0T9R4|A0A7P0T9R4_HUMAN,tr|A0A2R8Y5T0|A0A2R8Y5T0_HUMAN,tr|A0A7P0T990|A0A7P0T990_HUMAN,tr|A0A7P0T942|A0A7P0T942_HUMAN,tr|A0A2R8YFZ7|A0A2R8YFZ7_HUMAN,tr|A0A7P0T825|A0A7P0T825_HUMAN,tr|A0A2R8Y6H2|A0A2R8Y6H2_HUMAN,tr|A0A7P0TAM4|A0A7P0TAM4_HUMAN" 28 1027.5662 0.88 95519 6970 2 1027.566221 514.7904 Cytoplasmic dynein 1 heavy chain 1 OS=Homo sapiens OX=9606 GN=DYNC1H1 PE=1 SV=5 8.31 1676.9 - 337541 - - - 0.0117 - 1.448 0.092 - 215.3 1 2 0 0 9 0 0 0 7.46E+06 8.49E+06 - - - 0.7915 0.9997 221125_WJC_METTL3_EV_vs_WT_F07.06974.06974.2 0.00116 16-Oct R.HEIGELQQR.L "sp|P82094|TMF1_HUMAN,tr|A0A2R8Y7M0|A0A2R8Y7M0_HUMAN" 2 1108.5625 1.53 95521 6974 2 1108.562661 555.2885 TATA element modulatory factor OS=Homo sapiens OX=9606 GN=TMF1 PE=1 SV=2 5.4 1677.4 - 1.35E+06 - - - 0.1263 - 1.694 0.435 - 327 1 2 0 0.0001 9 0 0 0 8.04E+07 5.27E+07 - - - 3.7788 1 221125_WJC_METTL3_EV_vs_WT_F07.06977.06977.3 6.60E-09 19/56 R.LLAPEAGSHPQQTQK.L sp|Q8NFQ8|TOIP2_HUMAN 1 1603.8318 1.28 95524 6977 3 1603.831727 535.6179 Torsin-1A-interacting protein 2 OS=Homo sapiens OX=9606 GN=TOR1AIP2 PE=1 SV=1 6.75 1677.7 - 1.48E+06 - - - -0.0574 - 3.455 0.584 - 412.2 1 2 0 -0.0001 15 0 0 0 2.85E+07 2.23E+07 - - - 8.2861 1 221125_WJC_METTL3_EV_vs_WT_F07.06978.06978.2 0.00668 15/16 K.K[136.11]DDAITAYK[136.11].K "sp|Q9BY77|PDIP3_HUMAN,tr|F6VRR5|F6VRR5_HUMAN" 2 1039.5521 1.6 95525 6978 2 1039.551749 520.7833 Polymerase delta-interacting protein 3 OS=Homo sapiens OX=9606 GN=POLDIP3 PE=1 SV=2 5.96 1677.8 - 939878 - - - -0.3146 - 3.105 0.486 - 757.5 1 2 0 -0.0003 9 0 0 0 1.35E+08 8.47E+07 - - - 5.9084 1 221125_WJC_METTL3_EV_vs_WT_F07.06980.06980.2 6.61E-05 13/20 K.VEEHEETFEEK.L "sp|P07197|NFM_HUMAN,tr|E7ESP9|E7ESP9_HUMAN,tr|E7EMV2|E7EMV2_HUMAN" 3 1404.6045 2.56 95527 6980 2 1404.60276 703.3095 Neurofilament medium polypeptide OS=Homo sapiens OX=9606 GN=NEFM PE=1 SV=3 4.2 1678.1 - 497301 - - - -1.2423 - 2.828 0.558 - 803.1 1 2 0 -0.0017 11 0 0 0 8.56E+06 3.35E+06 - - - 5.9741 0.9998 221125_WJC_METTL3_EV_vs_WT_F07.06993.06993.3 1.33E-05 Dec-44 R.LVSSDPEINTKK.L sp|Q9Y266|NUDC_HUMAN 1 1329.714 0.62 95536 6993 3 1329.711028 444.2453 Nuclear migration protein nudC OS=Homo sapiens OX=9606 GN=NUDC PE=1 SV=1 6.07 1679.7 - 885455 - - - -2.2321 - 1.996 0.445 - 209.3 1 2 0 -0.003 12 0 0 0 1.63E+07 2.63E+07 - - - 5.4162 0.7735 221125_WJC_METTL3_EV_vs_WT_F07.07003.07003.2 0.161 18-Dec Q.MK[136.11]ETIMNQEK[136.11].L "sp|P20290|BTF3_HUMAN,tr|A0A7I2V3T6|A0A7I2V3T6_HUMAN,tr|D6RDG3|D6RDG3_HUMAN,tr|A0A7I2YQL2|A0A7I2YQL2_HUMAN" 4 1266.6283 1.05 95543 7003 2 1266.62968 634.3214 Transcription factor BTF3 OS=Homo sapiens OX=9606 GN=BTF3 PE=1 SV=1 5.9 1681 - 889253 - - - 1.0942 - 2.301 0.292 - 331.4 1 1 1 0.0014 10 0 0 0 3.21E+07 3.05E+07 - - - 3.5234 0.9995 221125_WJC_METTL3_EV_vs_WT_F07.07005.07005.2 0.00107 24-Sep R.NSC[160.03]NVGGGGGGFK[136.11].H sp|Q7L2J0|MEPCE_HUMAN 1 1217.5339 0.001 95545 7005 2 1217.535258 609.7742 7SK snRNA methylphosphate capping enzyme OS=Homo sapiens OX=9606 GN=MEPCE PE=1 SV=1 8.22 1681.2 - 256699 - - - 1.14 - 1.421 0.456 - 160.4 1 2 0 0.0014 13 0 0 0 0.00E+00 3.69E+06 - - - 3.3104 0.9999 221125_WJC_METTL3_EV_vs_WT_F07.07006.07006.2 1.99E-05 20-Oct R.EGQNYQQNC[160.03]IK.E "sp|O96000|NDUBA_HUMAN,tr|H3BPJ9|H3BPJ9_HUMAN,tr|H3BV16|H3BV16_HUMAN" 3 1380.6092 2 95546 7006 2 1380.608254 691.3119 NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 10 OS=Homo sapiens OX=9606 GN=NDUFB10 PE=1 SV=3 6.09 1681.3 - 250628 - - - -0.6946 - 2.056 0.577 - 483.9 1 2 0 -0.001 11 0 0 0 2.84E+07 1.42E+07 - - - 5.2523 1 221125_WJC_METTL3_EV_vs_WT_F07.07012.07012.3 4.42E-05 Nov-40 K.DVIEEHGPSEK.A "sp|P51114|FXR1_HUMAN,tr|H7C4S4|H7C4S4_HUMAN,tr|B4DXZ6|B4DXZ6_HUMAN" 3 1238.5779 3.66 95550 7012 3 1238.577445 413.8666 Fragile X mental retardation syndrome-related protein 1 OS=Homo sapiens OX=9606 GN=FXR1 PE=1 SV=3 4.4 1682 - 2.47E+06 - - - -0.3641 - 2.262 0.453 - 128.4 1 2 0 -0.0005 11 0 0 0 2.06E+08 5.63E+07 - - - 5.9092 0.9993 221125_WJC_METTL3_EV_vs_WT_F07.07021.07021.2 0.00145 20-Aug K.DVIEEHGPSEK.A "sp|P51114|FXR1_HUMAN,tr|H7C4S4|H7C4S4_HUMAN,tr|B4DXZ6|B4DXZ6_HUMAN" 3 1238.5779 1.33 95557 7021 2 1238.57795 620.2962 Fragile X mental retardation syndrome-related protein 1 OS=Homo sapiens OX=9606 GN=FXR1 PE=1 SV=3 4.4 1683 - 529335 - - - 0.0436 - 1.46 0.348 - 143.9 1 2 0 0.0001 11 0 0 0 1.50E+07 1.13E+07 - - - 2.6351 0.9993 221125_WJC_METTL3_EV_vs_WT_F07.07022.07022.2 5.01E-05 20-Oct R.EGQNYQQNC[160.03]IK[136.11].E "sp|O96000|NDUBA_HUMAN,tr|H3BPJ9|H3BPJ9_HUMAN,tr|H3BV16|H3BV16_HUMAN" 3 1388.6234 2 95558 7022 2 1388.627206 695.319 NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 10 OS=Homo sapiens OX=9606 GN=NDUFB10 PE=1 SV=3 6.09 1683.1 - 488238 - - - 2.7315 - 1.999 0.434 - 518.4 1 2 0 0.0038 11 0 0 0 2.84E+07 1.42E+07 - - - 4.1191 0.9756 221125_WJC_METTL3_EV_vs_WT_F07.07025.07025.2 0.112 20-Jun R.VKVEPAVDTSR.L "sp|O75369|FLNB_HUMAN,tr|E7EN95|E7EN95_HUMAN,tr|A0A804HK76|A0A804HK76_HUMAN,tr|A0A804HL72|A0A804HL72_HUMAN" 4 1199.651 0.74 95561 7025 2 1199.651782 600.8328 Filamin-B OS=Homo sapiens OX=9606 GN=FLNB PE=1 SV=2 6.04 1683.5 - 226071 - - - 0.651 - 1.301 0.279 - 83.3 1 2 1 0.0008 11 0 0 0 1.27E+06 1.72E+06 - - - 1.8133 0.9875 221125_WJC_METTL3_EV_vs_WT_F07.07028.07028.3 0.0953 Oct-40 K.QVLDGK[136.11]EEVEK[136.11].Q "sp|P82094|TMF1_HUMAN,tr|F8WF45|F8WF45_HUMAN" 2 1288.6845 1.7 95562 7028 3 1288.68409 430.5688 TATA element modulatory factor OS=Homo sapiens OX=9606 GN=TMF1 PE=1 SV=2 4.41 1683.9 - 2.05E+06 - - - -0.3538 - 1.71 0.229 - 125 1 2 1 -0.0005 11 0 0 0 1.79E+08 1.06E+08 - - - 2.6171 0.9997 221125_WJC_METTL3_EV_vs_WT_F07.07029.07029.3 0.00194 Sep-36 K.VVSTHEQVLR.T sp|P02533|K1C14_HUMAN 1 1166.6408 13.85 95563 7029 3 1166.640925 389.8875 "Keratin, type I cytoskeletal 14 OS=Homo sapiens OX=9606 GN=KRT14 PE=1 SV=4" 6.72 1684 - 1.13E+06 - - - 0.132 - 1.897 0.352 - 154.7 1 2 0 0.0002 10 0 0 0 1.93E+07 1.39E+06 - - - 4.3343 0.796 221125_WJC_METTL3_EV_vs_WT_F07.07031.07031.2 0.452 20-Oct M.IASDSHRPEVK.L "sp|Q9NYF8|BCLF1_HUMAN,tr|E9PKI6|E9PKI6_HUMAN,tr|A0A1W2PQ43|A0A1W2PQ43_HUMAN,tr|E9PK91|E9PK91_HUMAN,tr|E9PJA7|E9PJA7_HUMAN,tr|E9PK09|E9PK09_HUMAN,tr|E9PQN2|E9PQN2_HUMAN" 7 1237.6415 20.23 95565 7031 2 1237.642718 619.828 Bcl-2-associated transcription factor 1 OS=Homo sapiens OX=9606 GN=BCLAF1 PE=1 SV=2 6.75 1684.1 - 519811 - - - 0.9849 - 1.238 0.244 - 139.4 1 1 0 0.0012 11 0 0 0 3.52E+08 1.74E+07 - - - 1.4204 0.9957 221125_WJC_METTL3_EV_vs_WT_F07.07032.07032.2 0.00307 20-Jul K.QVLDGK[136.11]EEVEK[136.11].Q "sp|P82094|TMF1_HUMAN,tr|F8WF45|F8WF45_HUMAN" 2 1288.6845 1.68 95566 7032 2 1288.683805 645.3495 TATA element modulatory factor OS=Homo sapiens OX=9606 GN=TMF1 PE=1 SV=2 4.41 1684.3 - 368549 - - - -0.575 - 1.631 0.404 - 149.8 1 2 1 -0.0007 11 0 0 0 2.67E+07 1.59E+07 - - - 3.3481 0.9774 221125_WJC_METTL3_EV_vs_WT_F07.07033.07033.2 0.0283 22-Sep R.IK[136.11]ENGAAALDGR[166.11].L "sp|P57105|SYJ2B_HUMAN,tr|A0A087X1F5|A0A087X1F5_HUMAN,tr|A0A087WYV9|A0A087WYV9_HUMAN" 3 1231.664 1.66 95567 7033 2 1231.6683 616.8393 Synaptojanin-2-binding protein OS=Homo sapiens OX=9606 GN=SYNJ2BP PE=1 SV=2 6.07 1684.4 - 225605 - - - 3.5164 - 1.806 0.399 - 176.6 1 2 1 0.0043 12 0 0 0 4.60E+06 2.77E+06 - - - 3.542 0.9041 221125_WJC_METTL3_EV_vs_WT_F07.07039.07039.3 0.0237 Aug-44 R.IK[136.11]ENGAAALDGR[166.11].L "sp|P57105|SYJ2B_HUMAN,tr|A0A087X1F5|A0A087X1F5_HUMAN,tr|A0A087WYV9|A0A087WYV9_HUMAN" 3 1231.664 1.45 95571 7039 3 1231.663484 411.5619 Synaptojanin-2-binding protein OS=Homo sapiens OX=9606 GN=SYNJ2BP PE=1 SV=2 6.07 1685 - 1.37E+06 - - - -0.3938 - 1.781 0.106 - 107.7 1 2 1 -0.0005 12 0 0 0 2.65E+07 1.83E+07 - - - 1.3215 0.9974 221125_WJC_METTL3_EV_vs_WT_F07.07040.07040.2 0.000741 20-Nov K.QVLDGKEEVEK.Q "sp|P82094|TMF1_HUMAN,tr|F8WF45|F8WF45_HUMAN" 2 1272.6561 1.68 95572 7040 2 1272.65657 637.3353 TATA element modulatory factor OS=Homo sapiens OX=9606 GN=TMF1 PE=1 SV=2 4.41 1685.1 - 956547 - - - 0.3332 - 2.175 0.376 - 387.1 1 2 1 0.0004 11 0 0 0 2.67E+07 1.59E+07 - - - 3.92 0.9936 221125_WJC_METTL3_EV_vs_WT_F07.07041.07041.2 0.0546 16-Aug K.RTSIETNIR.V "sp|P14859|PO2F1_HUMAN,sp|Q9UKI9|PO2F3_HUMAN,tr|H0YLC5|H0YLC5_HUMAN,tr|A0A0C4DG88|A0A0C4DG88_HUMAN,tr|A0A0A0MT46|A0A0A0MT46_HUMAN" 5 1088.5938 1.87 95573 7041 2 1088.595524 545.3042 "POU domain, class 2, transcription factor 1 OS=Homo sapiens OX=9606 GN=POU2F1 PE=1 SV=2" 9.6 1685.2 - 396903 - - - 1.5644 - 1.516 0.167 - 99 2 2 0 0.0017 9 0 0 0 1.86E+07 9.97E+06 - - - 1.3432 0.9923 221125_WJC_METTL3_EV_vs_WT_F07.07043.07043.2 3.12E-06 20-Sep R.FTC[160.03]SESQVNSR[166.11].P sp|P11717|MPRI_HUMAN 1 1323.5753 0.84 95575 7043 2 1323.57344 662.7949 Cation-independent mannose-6-phosphate receptor OS=Homo sapiens OX=9606 GN=IGF2R PE=1 SV=3 5.99 1685.5 - 182934 - - - -1.3932 - 2.037 0.615 - 399.5 1 1 0 -0.0018 11 0 0 0 2.42E+06 2.87E+06 - - - 5.5075 0.9956 221125_WJC_METTL3_EV_vs_WT_F07.07050.07050.3 0.112 Nov-40 K.TEELKPQVEEK.N "sp|Q9UN86|G3BP2_HUMAN,tr|A0A7I2V3E2|A0A7I2V3E2_HUMAN,tr|A0A7I2V647|A0A7I2V647_HUMAN,tr|A0A7I2YQS2|A0A7I2YQS2_HUMAN,tr|A0A7I2YQD9|A0A7I2YQD9_HUMAN,tr|A0A7I2V3P9|A0A7I2V3P9_HUMAN" 6 1328.6824 1.53 95580 7050 3 1328.680306 443.9014 Ras GTPase-activating protein-binding protein 2 OS=Homo sapiens OX=9606 GN=G3BP2 PE=1 SV=2 4.49 1686.2 - 1.50E+06 - - - -1.5466 - 2.066 0.17 - 151.9 1 2 0 -0.0021 11 0 0 0 4.32E+08 2.83E+08 - - - 2.4961 0.9963 221125_WJC_METTL3_EV_vs_WT_F07.07053.07053.2 0.0173 13/18 R.VRVELSNGEK.R sp|P84103|SRSF3_HUMAN 1 1129.6091 1.37 95583 7053 2 1129.609866 565.8118 Serine\arginine-rich splicing factor 3 OS=Homo sapiens OX=9606 GN=SRSF3 PE=1 SV=1 6.11 1686.6 - 389210 - - - 0.6454 - 2.169 0.328 - 486.4 1 2 1 0.0007 10 0 0 0 7.63E+07 5.55E+07 - - - 3.6246 0.9951 221125_WJC_METTL3_EV_vs_WT_F07.07054.07054.2 0.0261 13/18 R.VR[166.11]VELSNGEK[136.11].R sp|P84103|SRSF3_HUMAN 1 1147.6316 1.37 95584 7054 2 1147.633542 574.8231 Serine\arginine-rich splicing factor 3 OS=Homo sapiens OX=9606 GN=SRSF3 PE=1 SV=1 6.11 1686.7 - 386596 - - - 1.6861 - 2.478 0.316 - 445.6 1 2 1 0.0019 10 0 0 0 7.63E+07 5.55E+07 - - - 3.9073 0.9996 221125_WJC_METTL3_EV_vs_WT_F07.07059.07059.3 0.00355 Dec-36 R.VR[166.11]VELSNGEK[136.11].R sp|P84103|SRSF3_HUMAN 1 1147.6316 0.001 95587 7059 3 1147.63067 383.5511 Serine\arginine-rich splicing factor 3 OS=Homo sapiens OX=9606 GN=SRSF3 PE=1 SV=1 6.11 1687.4 - 5.07E+06 - - - -0.8165 - 2.434 0.375 - 269.3 1 2 1 -0.0009 10 0 0 0 0.00E+00 2.46E+08 - - - 5.3185 0.9846 221125_WJC_METTL3_EV_vs_WT_F07.07060.07060.3 0.0893 Sep-40 R.IEGDNENK[136.11]LPR[166.11].E "sp|P51114|FXR1_HUMAN,tr|E7EU85|E7EU85_HUMAN,tr|E9PFF5|E9PFF5_HUMAN,tr|B4DXZ6|B4DXZ6_HUMAN" 4 1301.6694 1.67 95588 7060 3 1301.670472 434.8971 Fragile X mental retardation syndrome-related protein 1 OS=Homo sapiens OX=9606 GN=FXR1 PE=1 SV=3 4.68 1687.5 - 753275 - - - 0.7859 - 1.679 0.222 - 150.5 1 2 1 0.001 11 0 0 0 2.20E+08 1.31E+08 - - - 2.4869 0.9996 221125_WJC_METTL3_EV_vs_WT_F07.07065.07065.2 0.00403 20-Oct K.TEELK[136.11]PQVEEK[136.11].N "sp|Q9UN86|G3BP2_HUMAN,tr|A0A7I2V3E2|A0A7I2V3E2_HUMAN,tr|A0A7I2V647|A0A7I2V647_HUMAN,tr|A0A7I2YQS2|A0A7I2YQS2_HUMAN,tr|A0A7I2YQD9|A0A7I2YQD9_HUMAN,tr|A0A7I2V3P9|A0A7I2V3P9_HUMAN" 6 1344.7108 1.56 95593 7065 2 1344.707904 673.3627 Ras GTPase-activating protein-binding protein 2 OS=Homo sapiens OX=9606 GN=G3BP2 PE=1 SV=2 4.49 1688.1 - 252231 - - - -2.1246 - 2.179 0.414 - 325.3 1 2 0 -0.0029 11 0 0 0 4.21E+07 2.69E+07 - - - 4.2049 0.9989 221125_WJC_METTL3_EV_vs_WT_F07.07069.07069.3 0.00268 Sep-32 K.QC[160.03]EINYVK[136.11]K[136.11].F "sp|Q14331|FRG1_HUMAN,tr|E9PLY7|E9PLY7_HUMAN" 2 1196.6194 1.18 95595 7069 3 1196.618217 399.8804 Protein FRG1 OS=Homo sapiens OX=9606 GN=FRG1 PE=1 SV=1 8.18 1688.6 - 988271 - - - -1.0254 - 1.646 0.29 - 140.5 1 2 0 -0.0012 9 0 0 0 1.50E+07 1.27E+07 - - - 3.2748 0.9977 221125_WJC_METTL3_EV_vs_WT_F07.07070.07070.2 0.335 16-Oct K.R[166.11]TSIETNIR[166.11].V "sp|P14859|PO2F1_HUMAN,sp|Q9UKI9|PO2F3_HUMAN,tr|H0YLC5|H0YLC5_HUMAN,tr|A0A0C4DG88|A0A0C4DG88_HUMAN,tr|A0A0A0MT46|A0A0A0MT46_HUMAN" 5 1108.6104 1.87 95596 7070 2 1108.609832 555.3125 "POU domain, class 2, transcription factor 1 OS=Homo sapiens OX=9606 GN=POU2F1 PE=1 SV=2" 9.6 1688.7 - 597048 - - - -0.4772 - 1.456 0.233 - 170.7 2 2 0 -0.0005 9 0 0 0 1.86E+07 9.97E+06 - - - 1.7142 0.9999 221125_WJC_METTL3_EV_vs_WT_F07.07071.07071.2 8.51E-05 20-Nov K.TEELKPQVEEK.N "sp|Q9UN86|G3BP2_HUMAN,tr|A0A7I2V3E2|A0A7I2V3E2_HUMAN,tr|A0A7I2V647|A0A7I2V647_HUMAN,tr|A0A7I2YQS2|A0A7I2YQS2_HUMAN,tr|A0A7I2YQD9|A0A7I2YQD9_HUMAN,tr|A0A7I2V3P9|A0A7I2V3P9_HUMAN" 6 1328.6824 1.57 95597 7071 2 1328.682284 665.3485 Ras GTPase-activating protein-binding protein 2 OS=Homo sapiens OX=9606 GN=G3BP2 PE=1 SV=2 4.49 1688.8 - 467795 - - - -0.058 - 2.377 0.51 - 459 1 2 0 -0.0001 11 0 0 0 4.22E+07 2.69E+07 - - - 5.1501 0.9999 221125_WJC_METTL3_EV_vs_WT_F07.07074.07074.2 3.21E-05 30-Oct R.EPAQTEAAASTEPATR[166.11].R sp|Q8N8A6|DDX51_HUMAN 1 1638.7725 0.73 95600 7074 2 1638.77101 820.3935 ATP-dependent RNA helicase DDX51 OS=Homo sapiens OX=9606 GN=DDX51 PE=1 SV=3 4.25 1689.2 - 268622 - - - -0.8866 - 2.328 0.538 - 365.5 1 2 0 -0.0015 16 0 0 0 5.94E+06 8.17E+06 - - - 5.0917 0.9985 221125_WJC_METTL3_EV_vs_WT_F07.07077.07077.2 0.000268 20-Nov R.QAPQPQSSLQR[166.11].G "sp|Q8WXI9|P66B_HUMAN,tr|A0A0U1RRM1|A0A0U1RRM1_HUMAN,tr|A0A1B0GW07|A0A1B0GW07_HUMAN" 3 1248.645 1.78 95601 7077 2 1248.645875 625.3298 Transcriptional repressor p66-beta OS=Homo sapiens OX=9606 GN=GATAD2B PE=1 SV=1 9.75 1689.6 - 1.58E+06 - - - 0.6863 - 1.799 0.202 - 327.6 1 2 0 0.0009 11 0 0 0 6.28E+08 3.53E+08 - - - 2.1213 0.9949 221125_WJC_METTL3_EV_vs_WT_F07.07079.07079.3 0.00168 Dec-36 K.ETPDK[136.11]VELSK[136.11].E sp|Q13610|PWP1_HUMAN 1 1160.626 0.89 95603 7079 3 1160.624329 387.8826 Periodic tryptophan protein 1 homolog OS=Homo sapiens OX=9606 GN=PWP1 PE=1 SV=1 4.68 1689.8 - 915804 - - - -1.413 - 1.919 0.264 - 207.6 1 2 1 -0.0016 10 0 0 0 2.59E+07 2.92E+07 - - - 3.3864 0.9999 221125_WJC_METTL3_EV_vs_WT_F07.07084.07084.2 6.10E-07 22-Dec R.ENQEGAANVNVR[166.11].G sp|Q8N0X7|SPART_HUMAN 1 1309.625 1.2 95607 7084 2 1309.623785 655.8198 Spartin OS=Homo sapiens OX=9606 GN=SPART PE=1 SV=1 4.53 1690.5 - 904275 - - - -0.9361 - 2.331 0.582 - 562.8 1 2 0 -0.0012 12 0 0 0 1.15E+08 9.54E+07 - - - 5.566 0.9998 221125_WJC_METTL3_EV_vs_WT_F07.07086.07086.2 4.15E-06 22-Oct R.ENQEGAANVNVR.G sp|Q8N0X7|SPART_HUMAN 1 1299.6167 1.2 95608 7086 2 1299.616068 650.8156 Spartin OS=Homo sapiens OX=9606 GN=SPART PE=1 SV=1 4.53 1690.8 - 1.11E+06 - - - -0.5178 - 2.109 0.452 - 299.9 1 2 0 -0.0007 12 0 0 0 1.15E+08 9.54E+07 - - - 4.3427 0.9995 221125_WJC_METTL3_EV_vs_WT_F07.07087.07087.2 0.00263 22-Oct R.GGDGQINEQVEK[136.11].L sp|O75381|PEX14_HUMAN 1 1280.6088 1.16 95609 7087 2 1280.611253 641.3117 Peroxisomal membrane protein PEX14 OS=Homo sapiens OX=9606 GN=PEX14 PE=1 SV=1 4.14 1690.9 - 209797 - - - 1.9085 - 2.205 0.363 - 295 1 2 0 0.0024 12 0 0 0 8.36E+06 7.22E+06 - - - 3.8019 0.9858 221125_WJC_METTL3_EV_vs_WT_F07.07089.07089.2 0.0425 20-Aug K.QSLQNC[160.03]QNLSK.D "sp|Q3V6T2|GRDN_HUMAN,tr|A0A087WXD9|A0A087WXD9_HUMAN,tr|A0A2R8YG52|A0A2R8YG52_HUMAN,tr|A0A2U3TZV9|A0A2U3TZV9_HUMAN,tr|A0A2R8YG73|A0A2R8YG73_HUMAN,tr|A0A2R8YGU1|A0A2R8YGU1_HUMAN,tr|A0A2R8Y7D9|A0A2R8Y7D9_HUMAN,tr|A0A2R8Y6B2|A0A2R8Y6B2_HUMAN,tr|A0A2R8Y4X4|A0A2R8Y4X4_HUMAN,tr|A0A2R8Y4W8|A0A2R8Y4W8_HUMAN,tr|A0A2R8Y7B1|A0A2R8Y7B1_HUMAN" 11 1318.6299 4.38 95611 7089 2 1318.634806 660.3223 Girdin OS=Homo sapiens OX=9606 GN=CCDC88A PE=1 SV=2 8.22 1691.1 - 375911 - - - 3.6834 - 1.202 0.311 - 129.3 1 2 0 0.0049 11 0 0 0 4.82E+06 1.10E+06 - - - 1.8342 1 221125_WJC_METTL3_EV_vs_WT_F07.07090.07090.2 5.13E-09 30-Oct R.EPAQTEAAASTEPATR.R sp|Q8N8A6|DDX51_HUMAN 1 1628.7642 0.73 95612 7090 2 1628.767464 815.3894 ATP-dependent RNA helicase DDX51 OS=Homo sapiens OX=9606 GN=DDX51 PE=1 SV=3 4.25 1691.2 - 189851 - - - 2.0083 - 2.328 0.633 - 244.5 1 2 0 0.0033 16 0 0 0 5.94E+06 8.17E+06 - - - 5.7928 0.9488 221125_WJC_METTL3_EV_vs_WT_F07.07098.07098.3 1.17 Aug-40 R.SFSSQR[166.11]PGMER[166.11].Q sp|P48634|PRC2A_HUMAN 1 1300.6097 0.98 95616 7098 3 1300.610516 434.5438 Protein PRRC2A OS=Homo sapiens OX=9606 GN=PRRC2A PE=1 SV=3 9.31 1692.2 - 2.53E+06 - - - 0.6205 - 1.088 0.185 - 73.3 1 2 0 0.0008 11 0 0 0 9.36E+07 9.55E+07 - - - 0.8419 0.9763 221125_WJC_METTL3_EV_vs_WT_F07.07099.07099.2 0.66 18-Nov R.R[166.11]QLETLGQEK[136.11].L "sp|P05787|K2C8_HUMAN,tr|F8VUG2|F8VUG2_HUMAN,tr|F8VP67|F8VP67_HUMAN,tr|F8W1U3|F8W1U3_HUMAN" 4 1218.6687 2.26 95617 7099 2 1218.670381 610.3416 "Keratin, type II cytoskeletal 8 OS=Homo sapiens OX=9606 GN=KRT8 PE=1 SV=7" 6.14 1692.3 - 277993 - - - 1.363 - 1.302 0.077 - 314.6 1 2 0 0.0017 10 0 0 0 8.38E+06 3.71E+06 - - - 0.3458 0.7677 221125_WJC_METTL3_EV_vs_WT_F07.07101.07101.3 2.35 Jul-44 R.ENQEGAANVNVR[166.11].G sp|Q8N0X7|SPART_HUMAN 1 1309.625 3.94 95619 7101 3 1309.630106 437.5489 Spartin OS=Homo sapiens OX=9606 GN=SPART PE=1 SV=1 4.53 1692.6 - 267784 - - - 3.8904 - 1.327 0.15 - 86.6 1 2 0 0.0051 12 0 0 0 4.22E+07 1.07E+07 - - - 0.9952 0.9981 221125_WJC_METTL3_EV_vs_WT_F07.07108.07108.2 0.00476 22-Nov R.GGDGQINEQVEK.L sp|O75381|PEX14_HUMAN 1 1272.5946 1.15 95622 7108 2 1272.598876 637.3046 Peroxisomal membrane protein PEX14 OS=Homo sapiens OX=9606 GN=PEX14 PE=1 SV=1 4.14 1693.4 - 449098 - - - 3.353 - 2.125 0.339 - 563 1 2 0 0.0043 12 0 0 0 8.53E+06 7.43E+06 - - - 3.5268 0.9999 221125_WJC_METTL3_EV_vs_WT_F07.07122.07122.2 6.02E-06 20-Dec R.C[160.03]TDDFNGAQC[160.03]K[136.11].A "sp|P17980|PRS6A_HUMAN,tr|R4GNH3|R4GNH3_HUMAN,tr|E9PM69|E9PM69_HUMAN" 3 1322.5111 0.8 95632 7122 2 1322.509717 662.2628 26S proteasome regulatory subunit 6A OS=Homo sapiens OX=9606 GN=PSMC3 PE=1 SV=3 4.21 1695.1 - 288567 - - - -1.0352 - 2.185 0.526 - 485.9 1 2 0 -0.0014 11 0 0 0 6.72E+06 8.43E+06 - - - 5.0401 0.99 221125_WJC_METTL3_EV_vs_WT_F07.07123.07123.3 0.262 Sep-40 R.QAPQPQSSLQR.G "sp|Q8WXI9|P66B_HUMAN,tr|A0A0U1RRM1|A0A0U1RRM1_HUMAN,tr|A0A1B0GW07|A0A1B0GW07_HUMAN" 3 1238.6367 1.89 95633 7123 3 1238.638525 413.8862 Transcriptional repressor p66-beta OS=Homo sapiens OX=9606 GN=GATAD2B PE=1 SV=1 9.75 1695.2 - 430746 - - - 1.4346 - 1.605 0.19 - 90.6 1 2 0 0.0018 11 0 0 0 2.41E+07 1.28E+07 - - - 2.0019 0.9998 221125_WJC_METTL3_EV_vs_WT_F07.07126.07126.2 0.000119 24-Oct K.GGNASGEPGLDQR[166.11].A sp|Q7LBC6|KDM3B_HUMAN 1 1266.5828 1.25 95636 7126 2 1266.583535 634.2987 Lysine-specific demethylase 3B OS=Homo sapiens OX=9606 GN=KDM3B PE=1 SV=2 4.37 1695.6 - 248030 - - - 0.5708 - 2.007 0.509 - 361.1 1 2 0 0.0007 13 0 0 0 1.67E+07 1.33E+07 - - - 4.5882 0.9578 221125_WJC_METTL3_EV_vs_WT_F07.07127.07127.3 0.523 Aug-44 K.VSHSPALSSDVR.S "sp|Q68CP9|ARID2_HUMAN,tr|F8VWP4|F8VWP4_HUMAN,tr|F8W108|F8W108_HUMAN,tr|F8WCU9|F8WCU9_HUMAN" 4 1253.6364 0.72 95637 7127 3 1253.636859 418.8861 AT-rich interactive domain-containing protein 2 OS=Homo sapiens OX=9606 GN=ARID2 PE=1 SV=2 6.71 1695.7 - 206950 - - - 0.355 - 1.44 0.126 - 87.9 1 2 0 0.0004 12 0 0 0 6.17E+06 8.53E+06 - - - 0.9554 0.9997 221125_WJC_METTL3_EV_vs_WT_F07.07131.07131.2 0.0108 20-Sep K.ISYQSSSTEER.R "sp|P04279|SEMG1_HUMAN,sp|Q02383|SEMG2_HUMAN" 2 1285.5786 0.24 95639 7131 2 1285.578601 643.7966 Semenogelin-1 OS=Homo sapiens OX=9606 GN=SEMG1 PE=1 SV=2 4.53 1696.2 - 528170 - - - -0.0179 - 1.55 0.461 - 264.1 1 2 0 0 11 0 0 0 7.02E+06 2.88E+07 - - - 3.6315 0.9999 221125_WJC_METTL3_EV_vs_WT_F07.07132.07132.2 4.13E-05 24-Nov R.YSGSEGSTQTLTK.G sp|P25815|S100P_HUMAN 1 1357.6361 13.19 95640 7132 2 1357.635416 679.8253 Protein S100-P OS=Homo sapiens OX=9606 GN=S100P PE=1 SV=2 6 1696.3 - 307004 - - - -0.5325 - 2.478 0.584 - 260.7 1 2 0 -0.0007 13 0 0 0 1.10E+07 8.33E+05 - - - 5.6832 0.9295 221125_WJC_METTL3_EV_vs_WT_F07.07146.07146.3 6.07E-05 Sep-48 R.PAQPQEHPFASSR.F "sp|Q15437|SC23B_HUMAN,tr|Q5QPE2|Q5QPE2_HUMAN,tr|A0A2R8YFH5|A0A2R8YFH5_HUMAN" 3 1450.6953 1.01 95650 7146 3 1450.70106 484.5724 Protein transport protein Sec23B OS=Homo sapiens OX=9606 GN=SEC23B PE=1 SV=2 7.18 1698.1 - 360855 - - - 3.9526 - 2.184 0.413 - 76.5 1 1 0 0.0057 13 0 0 0 1.33E+07 1.31E+07 - - - 5.2609 0.9997 221125_WJC_METTL3_EV_vs_WT_F07.07147.07147.2 0.000992 22-Oct R.EVFTSSSSSSSR.Q sp|P08779|K1C16_HUMAN 1 1259.563 15.54 95651 7147 2 1259.562072 630.7888 "Keratin, type I cytoskeletal 16 OS=Homo sapiens OX=9606 GN=KRT16 PE=1 SV=4" 6.1 1698.3 - 717822 - - - -0.7161 - 1.863 0.433 - 322.7 1 2 0 -0.0009 12 0 0 0 3.39E+07 2.18E+06 - - - 3.8759 0.8273 221125_WJC_METTL3_EV_vs_WT_F07.07154.07154.2 2.69E-05 20-Aug K.GYSPTHREEEY.G sp|P20930|FILA_HUMAN 1 1366.579 999 95656 7154 2 1366.580513 684.2968 Filaggrin OS=Homo sapiens OX=9606 GN=FLG PE=1 SV=3 4.75 1699.2 - 189208 - - - 1.1371 - 1.557 0.504 - 229.4 1 1 1 0.0016 11 0 0 0 3.57E+06 0.00E+00 - - - 3.9608 0.9998 221125_WJC_METTL3_EV_vs_WT_F07.07158.07158.2 0.000168 14-Dec K.HQNVQLPR[166.11].E "sp|P26599|PTBP1_HUMAN,tr|A0A0U1RRM4|A0A0U1RRM4_HUMAN,tr|A6NLN1|A6NLN1_HUMAN,tr|A0A0D9SF20|A0A0D9SF20_HUMAN,tr|A0A7I2V621|A0A7I2V621_HUMAN,tr|K7EK45|K7EK45_HUMAN,tr|A0A087WUW5|A0A087WUW5_HUMAN" 7 1000.5442 0.85 95658 7158 2 1000.545678 501.2794 Polypyrimidine tract-binding protein 1 OS=Homo sapiens OX=9606 GN=PTBP1 PE=1 SV=1 9.76 1699.7 - 5.71E+06 - - - 1.4952 - 2.329 0.487 - 439.8 1 2 0 0.0015 8 0 0 0 6.37E+08 7.53E+08 - - - 5.1873 1 221125_WJC_METTL3_EV_vs_WT_F07.07161.07161.2 1.08E-07 22-Nov K.SYC[160.03]NDQSTGDIK[136.11].V sp|P00492|HPRT_HUMAN 1 1394.5864 0.6 95661 7161 2 1394.590088 698.3005 Hypoxanthine-guanine phosphoribosyltransferase OS=Homo sapiens OX=9606 GN=HPRT1 PE=1 SV=2 4.21 1700.1 - 267442 - - - 2.6739 - 2.271 0.639 - 287.4 1 2 0 0.0037 12 0 0 0 6.33E+06 1.05E+07 - - - 5.9176 0.9996 221125_WJC_METTL3_EV_vs_WT_F07.07165.07165.3 2.06E-06 Nov-40 R.IEGDNENKLPR.E "sp|P51114|FXR1_HUMAN,tr|E7EU85|E7EU85_HUMAN,tr|E9PFF5|E9PFF5_HUMAN,tr|B4DXZ6|B4DXZ6_HUMAN" 4 1283.647 1.66 95664 7165 3 1283.650602 428.8896 Fragile X mental retardation syndrome-related protein 1 OS=Homo sapiens OX=9606 GN=FXR1 PE=1 SV=3 4.68 1700.6 - 6.01E+06 - - - 2.8224 - 2.475 0.496 - 225.6 1 2 1 0.0036 11 0 0 0 2.17E+08 1.31E+08 - - - 6.6434 0.9998 221125_WJC_METTL3_EV_vs_WT_F07.07167.07167.2 2.13E-09 24-Dec R.NPGSSC[160.03]IGADPNR.N "sp|Q9UI42|CBPA4_HUMAN,tr|B7Z5J4|B7Z5J4_HUMAN" 2 1343.5888 999 95665 7167 2 1343.591238 672.8017 Carboxypeptidase A4 OS=Homo sapiens OX=9606 GN=CPA4 PE=1 SV=2 5.83 1700.8 - 386251 - - - 1.8056 - 2.44 0.562 - 367.4 1 2 0 0.0024 13 0 0 0 8.43E+06 0.00E+00 - - - 5.4805 0.9829 221125_WJC_METTL3_EV_vs_WT_F07.07168.07168.2 0.0132 22-Jul R.AR[166.11]GDSEALDEES.- "sp|Q7Z4V5|HDGR2_HUMAN,tr|A0A087WZ99|A0A087WZ99_HUMAN" 2 1287.5454 0.98 95666 7168 2 1287.547936 644.78 Hepatoma-derived growth factor-related protein 2 OS=Homo sapiens OX=9606 GN=HDGFL2 PE=1 SV=1 3.83 1701 - 258437 - - - 1.951 - 1.494 0.354 - 187 1 2 1 0.0025 12 0 0 0 6.07E+06 6.18E+06 - - - 2.7112 0.9986 221125_WJC_METTL3_EV_vs_WT_F07.07171.07171.3 0.0409 Sep-60 R.C[160.03]PGGLPGHAGGAAPGR[166.11].G sp|Q8N726|ARF_HUMAN 1 1440.692 4 95669 7171 3 1440.694262 481.2379 Tumor suppressor ARF OS=Homo sapiens OX=9606 GN=CDKN2A PE=1 SV=2 8.26 1701.2 - 726775 - - - 1.5798 - 1.577 0.326 - 41 1 2 0 0.0023 16 0 0 0 8.10E+07 2.02E+07 - - - 3.3428 0.9989 221125_WJC_METTL3_EV_vs_WT_F07.07174.07174.3 0.0024 Oct-44 K.LVDK[136.11]EDIDTSSK[136.11].G "sp|P78332|RBM6_HUMAN,tr|C9J250|C9J250_HUMAN,tr|E9PGM9|E9PGM9_HUMAN" 3 1364.7006 1.07 95670 7174 3 1364.703042 455.9075 RNA-binding protein 6 OS=Homo sapiens OX=9606 GN=RBM6 PE=1 SV=5 4.23 1701.7 - 945740 - - - 1.7967 - 2.089 0.387 - 128.7 1 2 1 0.0025 12 0 0 0 2.08E+07 1.94E+07 - - - 4.896 0.9998 221125_WJC_METTL3_EV_vs_WT_F07.07176.07176.2 8.77E-06 24-Dec K.GGNASGEPGLDQR.A sp|Q7LBC6|KDM3B_HUMAN 1 1256.5745 1.25 95672 7176 2 1256.57659 629.2945 Lysine-specific demethylase 3B OS=Homo sapiens OX=9606 GN=KDM3B PE=1 SV=2 4.37 1701.9 - 628308 - - - 1.6298 - 2.183 0.546 - 440 1 2 0 0.002 13 0 0 0 1.67E+07 1.33E+07 - - - 5.0768 0.939 221125_WJC_METTL3_EV_vs_WT_F07.07177.07177.3 1.05 Sep-56 R.GVPGTEPEK[136.11]DPGPR[166.11]A.- "sp|Q6QNY0|BL1S3_HUMAN,tr|K7EN58|K7EN58_HUMAN" 2 1523.7699 1.98 95673 7177 3 1523.770928 508.9306 Biogenesis of lysosome-related organelles complex 1 subunit 3 OS=Homo sapiens OX=9606 GN=BLOC1S3 PE=1 SV=1 4.68 1702 - 365963 - - - 0.6805 - 1.42 0.193 - 69.5 1 2 1 0.001 15 0 0 0 5.15E+07 2.60E+07 - - - 1.6065 0.9948 221125_WJC_METTL3_EV_vs_WT_F07.07182.07182.2 0.0209 20-Apr R.C[160.03]TDDFNGAQC[160.03]K.A "sp|P17980|PRS6A_HUMAN,tr|R4GNH3|R4GNH3_HUMAN,tr|E9PM69|E9PM69_HUMAN" 3 1314.4969 0.8 95677 7182 2 1314.500984 658.2557 26S proteasome regulatory subunit 6A OS=Homo sapiens OX=9606 GN=PSMC3 PE=1 SV=3 4.21 1702.6 - 87838.8 - - - 3.1175 - 0.959 0.461 - 46.9 1 2 0 0.0041 11 0 0 0 6.72E+06 8.43E+06 - - - 2.3314 0.9997 221125_WJC_METTL3_EV_vs_WT_F07.07184.07184.2 0.0127 14-Nov K.HQNVQLPR.E "sp|P26599|PTBP1_HUMAN,tr|A0A0U1RRM4|A0A0U1RRM4_HUMAN,tr|A6NLN1|A6NLN1_HUMAN,tr|A0A0D9SF20|A0A0D9SF20_HUMAN,tr|A0A7I2V621|A0A7I2V621_HUMAN,tr|K7EK45|K7EK45_HUMAN,tr|A0A087WUW5|A0A087WUW5_HUMAN" 7 990.5359 0.85 95678 7184 2 990.537272 496.2752 Polypyrimidine tract-binding protein 1 OS=Homo sapiens OX=9606 GN=PTBP1 PE=1 SV=1 9.76 1702.8 - 7.35E+06 - - - 1.373 - 2.023 0.437 - 393.2 1 2 0 0.0014 8 0 0 0 6.35E+08 7.49E+08 - - - 4.3932 0.9223 221125_WJC_METTL3_EV_vs_WT_F07.07185.07185.2 0.0729 16-Jun K.R[166.11]QGYGEGFR[166.11].W "sp|Q9NR31|SAR1A_HUMAN,sp|Q9Y6B6|SAR1B_HUMAN,tr|H0Y5E8|H0Y5E8_HUMAN,tr|Q9H029|Q9H029_HUMAN" 4 1088.5266 1.54 95679 7185 2 1088.530544 545.2706 GTP-binding protein SAR1a OS=Homo sapiens OX=9606 GN=SAR1A PE=1 SV=1 8.75 1703 - 273529 - - - 3.5948 - 1.314 0.121 - 66.6 3 2 0 0.0039 9 0 0 0 1.82E+07 1.18E+07 - - - 0.5104 0.988 221125_WJC_METTL3_EV_vs_WT_F07.07190.07190.2 0.000291 20-Sep R.IEGDNENK[136.11]LPR[166.11].E "sp|P51114|FXR1_HUMAN,tr|E7EU85|E7EU85_HUMAN,tr|E9PFF5|E9PFF5_HUMAN,tr|B4DXZ6|B4DXZ6_HUMAN" 4 1301.6694 2.51 95682 7190 2 1301.673569 651.842 Fragile X mental retardation syndrome-related protein 1 OS=Homo sapiens OX=9606 GN=FXR1 PE=1 SV=3 4.68 1703.6 - 247761 - - - 3.1652 - 1.873 0.445 - 310.4 1 2 1 0.0041 11 0 0 0 1.63E+07 6.50E+06 - - - 4.0241 0.9976 221125_WJC_METTL3_EV_vs_WT_F07.07191.07191.2 1.73E-06 22-Nov K.LVDK[136.11]EDIDTSSK[136.11].G "sp|P78332|RBM6_HUMAN,tr|C9J250|C9J250_HUMAN,tr|E9PGM9|E9PGM9_HUMAN" 3 1364.7006 1.33 95683 7191 2 1364.702754 683.3576 RNA-binding protein 6 OS=Homo sapiens OX=9606 GN=RBM6 PE=1 SV=5 4.23 1703.7 - 130603 - - - 1.5857 - 2.037 0.539 - 421.9 1 2 1 0.0022 12 0 0 0 2.30E+06 1.73E+06 - - - 4.8934 0.8887 221125_WJC_METTL3_EV_vs_WT_F07.07202.07202.3 1.14 Sep-56 R.GVPGTEPEKDPGPRA.- "sp|Q6QNY0|BL1S3_HUMAN,tr|K7EN58|K7EN58_HUMAN" 2 1505.7474 1.98 95690 7202 3 1505.747952 502.9231 Biogenesis of lysosome-related organelles complex 1 subunit 3 OS=Homo sapiens OX=9606 GN=BLOC1S3 PE=1 SV=1 4.68 1705.1 - 1.90E+06 - - - 0.3526 - 1.284 0.195 - 57.4 2 2 1 0.0005 15 0 0 0 5.15E+07 2.60E+07 - - - 1.2269 0.9819 221125_WJC_METTL3_EV_vs_WT_F07.07205.07205.2 0.00932 16-Sep K.HEASEIQIK[136.11].Q sp|Q15643|TRIPB_HUMAN 1 1061.5597 1.18 95693 7205 2 1061.565834 531.7871 Thyroid receptor-interacting protein 11 OS=Homo sapiens OX=9606 GN=TRIP11 PE=1 SV=3 5.4 1705.5 - 213992 - - - 5.8028 - 1.699 0.322 - 235.1 1 2 0 0.0062 9 0 0 0 2.42E+08 2.05E+08 - - - 2.9508 0.9995 221125_WJC_METTL3_EV_vs_WT_F07.07206.07206.2 0.000107 22-Oct R.AEQMASVQNAQR.D "sp|Q9UDY2|ZO2_HUMAN,tr|A0A3B3IT83|A0A3B3IT83_HUMAN,tr|A0A2R8YDH4|A0A2R8YDH4_HUMAN,tr|A0A3B3IS03|A0A3B3IS03_HUMAN,tr|A0A3B3ISF1|A0A3B3ISF1_HUMAN,tr|A0A1B0GTW1|A0A1B0GTW1_HUMAN,tr|A0A3B3ISZ5|A0A3B3ISZ5_HUMAN,tr|A0A3B3IRV6|A0A3B3IRV6_HUMAN,tr|A0A3B3IU51|A0A3B3IU51_HUMAN,tr|A0A3B3IRI3|A0A3B3IRI3_HUMAN,tr|A0A3B3ITE1|A0A3B3ITE1_HUMAN" 11 1331.6252 0.5 95694 7206 2 1331.629409 666.8199 Tight junction protein ZO-2 OS=Homo sapiens OX=9606 GN=TJP2 PE=1 SV=2 6.05 1705.6 - 206891 - - - 3.1631 - 2.299 0.547 - 474.9 1 2 0 0.0042 12 0 0 0 3.05E+06 6.14E+06 - - - 5.2702 0.9989 221125_WJC_METTL3_EV_vs_WT_F07.07210.07210.2 5.36E-05 14/22 K.IDDIRKPGESEE.- "sp|P48643|TCPE_HUMAN,tr|E9PCA1|E9PCA1_HUMAN,tr|B7ZAR1|B7ZAR1_HUMAN,tr|E7ENZ3|E7ENZ3_HUMAN" 4 1386.6627 0.63 95696 7210 2 1386.663003 694.3386 T-complex protein 1 subunit epsilon OS=Homo sapiens OX=9606 GN=CCT5 PE=1 SV=1 4.37 1706.2 - 860178 - - - 0.2272 - 2.475 0.52 - 389 1 2 1 0.0003 12 0 0 0 9.85E+07 1.56E+08 - - - 5.2661 0.9995 221125_WJC_METTL3_EV_vs_WT_F07.07211.07211.3 0.00234 Oct-40 K.EISSHGLPSDK.A "sp|Q03001|DYST_HUMAN,tr|E9PHM6|E9PHM6_HUMAN,tr|A0A494C1D7|A0A494C1D7_HUMAN,tr|F8W9J4|F8W9J4_HUMAN,tr|A0A7P0T890|A0A7P0T890_HUMAN,tr|F6QMI7|F6QMI7_HUMAN" 6 1168.5724 1.53 95697 7211 3 1168.57277 390.5314 Dystonin OS=Homo sapiens OX=9606 GN=DST PE=1 SV=4 5.32 1706.3 - 472695 - - - 0.3021 - 1.823 0.318 - 114.8 1 2 0 0.0004 11 0 0 0 1.06E+07 6.91E+06 - - - 3.7912 0.9994 221125_WJC_METTL3_EV_vs_WT_F07.07212.07212.2 0.00151 16-Sep K.HEASEIQIK.Q sp|Q15643|TRIPB_HUMAN 1 1053.5455 1.18 95698 7212 2 1053.546802 527.78 Thyroid receptor-interacting protein 11 OS=Homo sapiens OX=9606 GN=TRIP11 PE=1 SV=3 5.4 1706.5 - 438239 - - - 1.2605 - 1.918 0.32 - 228 1 2 0 0.0013 9 0 0 0 2.42E+08 2.05E+08 - - - 3.2883 0.9998 221125_WJC_METTL3_EV_vs_WT_F07.07217.07217.3 2.92E-05 Nov-44 K.AVAHHTTAAFIR[166.11].V sp|P43686|PRS6B_HUMAN 1 1303.7025 0.92 95701 7217 3 1303.70523 435.5748 26S proteasome regulatory subunit 6B OS=Homo sapiens OX=9606 GN=PSMC4 PE=1 SV=2 9.81 1707.1 - 1.67E+06 - - - 2.114 - 2.234 0.402 - 161.6 1 2 0 0.0028 12 0 0 0 8.54E+07 9.23E+07 - - - 5.2491 0.9994 221125_WJC_METTL3_EV_vs_WT_F07.07218.07218.3 1.19E-06 13/44 K.VPLKVEQANNAR.D "sp|Q9UM54|MYO6_HUMAN,tr|A0A590UK86|A0A590UK86_HUMAN,tr|A0A590UK71|A0A590UK71_HUMAN,tr|A0A0D9SGC1|A0A0D9SGC1_HUMAN,tr|A0A0A0MRM8|A0A0A0MRM8_HUMAN,tr|A0A5F9ZI03|A0A5F9ZI03_HUMAN,tr|A0A590UK22|A0A590UK22_HUMAN,tr|A0A590UJY4|A0A590UJY4_HUMAN,tr|A0A590UJ40|A0A590UJ40_HUMAN,tr|A0A590UJ75|A0A590UJ75_HUMAN,tr|E7EW20|E7EW20_HUMAN,tr|A0A590UKB0|A0A590UKB0_HUMAN,tr|A0A1Y0BRN3|A0A1Y0BRN3_HUMAN" 13 1337.7415 1.03 95702 7218 3 1337.743998 446.9211 Unconventional myosin-VI OS=Homo sapiens OX=9606 GN=MYO6 PE=1 SV=4 8.72 1707.2 - 525708 - - - 1.8314 - 2.538 0.387 - 253.2 1 2 1 0.0024 12 0 0 0 1.88E+07 1.82E+07 - - - 5.4356 0.9978 221125_WJC_METTL3_EV_vs_WT_F07.07223.07223.2 3.72E-05 22-Aug K.GTQSLPTASASK[136.11].F sp|Q9Y679|AUP1_HUMAN 1 1154.6023 1.1 95705 7223 2 1154.603496 578.3084 Lipid droplet-regulating VLDL assembly factor AUP1 OS=Homo sapiens OX=9606 GN=AUP1 PE=1 SV=2 8.75 1707.8 - 200480 - - - 1.0644 - 1.639 0.218 - 180.4 1 2 0 0.0012 12 0 0 0 2.49E+07 2.26E+07 - - - 1.9508 0.9984 221125_WJC_METTL3_EV_vs_WT_F07.07224.07224.2 0.014 22-Aug K.GTQSLPTASASK.F sp|Q9Y679|AUP1_HUMAN 1 1146.5881 1.1 95706 7224 2 1146.589476 574.3013 Lipid droplet-regulating VLDL assembly factor AUP1 OS=Homo sapiens OX=9606 GN=AUP1 PE=1 SV=2 8.75 1708 - 231069 - - - 1.2289 - 1.341 0.34 - 161.3 1 2 0 0.0014 12 0 0 0 2.49E+07 2.26E+07 - - - 2.3238 1 221125_WJC_METTL3_EV_vs_WT_F07.07225.07225.3 7.86E-06 Nov-44 K.AVAHHTTAAFIR.V sp|P43686|PRS6B_HUMAN 1 1293.6942 0.88 95707 7225 3 1293.695427 432.2387 26S proteasome regulatory subunit 6B OS=Homo sapiens OX=9606 GN=PSMC4 PE=1 SV=2 9.81 1708 - 2.01E+06 - - - 0.9454 - 2.088 0.498 - 177.9 1 2 0 0.0012 12 0 0 0 8.71E+07 9.86E+07 - - - 6.1325 0.9862 221125_WJC_METTL3_EV_vs_WT_F07.07230.07230.3 0.00126 Nov-44 K.PHSVSLNDTETR[166.11].K sp|Q9P0L0|VAPA_HUMAN 1 1364.656 1.22 95710 7230 3 1364.658155 455.8926 Vesicle-associated membrane protein-associated protein A OS=Homo sapiens OX=9606 GN=VAPA PE=1 SV=3 5.33 1708.7 - 704093 - - - 1.596 - 2.108 0.423 - 210 1 1 0 0.0022 12 0 0 0 3.52E+07 2.88E+07 - - - 5.3225 0.9998 221125_WJC_METTL3_EV_vs_WT_F07.07235.07235.2 0.000204 20-Sep R.EAGEQGDIEPR.R "sp|Q13283|G3BP1_HUMAN,tr|A0A7I2V5M7|A0A7I2V5M7_HUMAN,tr|A0A7I2V496|A0A7I2V496_HUMAN,tr|A0A7I2V2X7|A0A7I2V2X7_HUMAN,tr|A0A7P0P2U7|A0A7P0P2U7_HUMAN,tr|A0A7I2V548|A0A7I2V548_HUMAN,tr|A0A7I2YQN9|A0A7I2YQN9_HUMAN" 7 1199.5418 0.1 95713 7235 2 1199.541355 600.7782 Ras GTPase-activating protein-binding protein 1 OS=Homo sapiens OX=9606 GN=G3BP1 PE=1 SV=1 4 1709.3 - 189756 - - - -0.4085 - 1.719 0.529 - 293.2 1 2 0 -0.0005 11 0 0 0 1.13E+07 1.08E+08 - - - 4.4136 0.9997 221125_WJC_METTL3_EV_vs_WT_F07.07239.07239.2 0.000411 16-Sep K.DDAITAYK[136.11]K[136.11].Y "sp|Q9BY77|PDIP3_HUMAN,tr|F6VRR5|F6VRR5_HUMAN" 2 1039.5521 1.67 95715 7239 2 1039.553003 520.7833 Polymerase delta-interacting protein 3 OS=Homo sapiens OX=9606 GN=POLDIP3 PE=1 SV=2 5.96 1709.9 - 514906 - - - 0.8917 - 1.754 0.452 - 388.8 1 2 0 0.0009 9 0 0 0 1.63E+07 9.78E+06 - - - 4.0048 0.9942 221125_WJC_METTL3_EV_vs_WT_F07.07242.07242.2 0.0425 22-Jun K.AVAHHTTAAFIR[166.11].V sp|P43686|PRS6B_HUMAN 1 1303.7025 0.91 95718 7242 2 1303.704779 652.8585 26S proteasome regulatory subunit 6B OS=Homo sapiens OX=9606 GN=PSMC4 PE=1 SV=2 9.81 1710.3 - 148557 - - - 1.768 - 1.232 0.259 - 121.3 1 2 0 0.0023 12 0 0 0 2.71E+06 2.98E+06 - - - 1.5022 0.9508 221125_WJC_METTL3_EV_vs_WT_F07.07245.07245.3 0.175 Aug-40 K.NSLTSKDPDIK.A "sp|Q14974|IMB1_HUMAN,tr|J3QR48|J3QR48_HUMAN" 2 1216.6299 1.15 95719 7245 3 1216.629706 406.5506 Importin subunit beta-1 OS=Homo sapiens OX=9606 GN=KPNB1 PE=1 SV=2 5.96 1710.7 - 2.49E+06 - - - -0.1858 - 1.517 0.181 - 104.1 1 2 1 -0.0002 11 0 0 0 3.42E+08 2.98E+08 - - - 1.7418 0.9998 221125_WJC_METTL3_EV_vs_WT_F07.07251.07251.2 1.09E-06 20-Aug R.GQQSAEEENFK.K "sp|Q15014|MO4L2_HUMAN,tr|Q5JXX2|Q5JXX2_HUMAN,tr|Q5JXX1|Q5JXX1_HUMAN,tr|Q5JXX6|Q5JXX6_HUMAN" 4 1265.5524 0.44 95722 7251 2 1265.549887 633.7835 Mortality factor 4-like protein 2 OS=Homo sapiens OX=9606 GN=MORF4L2 PE=1 SV=1 4.25 1711.4 - 217732 - - - -1.9936 - 1.954 0.598 - 242.1 1 2 0 -0.0025 11 0 0 0 5.99E+06 1.37E+07 - - - 5.2692 0.9879 221125_WJC_METTL3_EV_vs_WT_F07.07254.07254.3 0.0265 Jul-36 K.C[160.03]LKNEYVENR.T sp|Q9NRP2|COXM2_HUMAN 1 1323.6241 1.07 95723 7254 3 1323.625166 442.2153 COX assembly mitochondrial protein 2 homolog OS=Homo sapiens OX=9606 GN=CMC2 PE=1 SV=1 6.14 1711.8 - 332846 - - - 0.7789 - 1.434 0.274 - 79.1 1 2 1 0.001 10 0 0 0 1.12E+07 1.05E+07 - - - 2.6473 0.9985 221125_WJC_METTL3_EV_vs_WT_F07.07257.07257.2 0.0789 20-Aug K.VEQATK[136.11]PSFER[166.11].G "sp|Q96E39|RMXL1_HUMAN,tr|A0A1B0GUK8|A0A1B0GUK8_HUMAN" 2 1308.6793 1.21 95725 7257 2 1308.680969 655.3469 "RNA binding motif protein, X-linked-like-1 OS=Homo sapiens OX=9606 GN=RBMXL1 PE=1 SV=1" 6.11 1712.2 - 125331 - - - 1.2868 - 1.509 0.306 - 107.4 1 2 0 0.0017 11 0 0 0 4.17E+06 3.46E+06 - - - 2.4136 0.9999 221125_WJC_METTL3_EV_vs_WT_F07.07258.07258.3 0.0028 13/40 K.VEQATKPSFER.G "sp|Q96E39|RMXL1_HUMAN,tr|A0A1B0GUK8|A0A1B0GUK8_HUMAN" 2 1290.6568 1.15 95726 7258 3 1290.655952 431.2262 "RNA binding motif protein, X-linked-like-1 OS=Homo sapiens OX=9606 GN=RBMXL1 PE=1 SV=1" 6.11 1712.3 - 3.02E+06 - - - -0.6687 - 2.343 0.353 - 236 1 2 0 -0.0009 11 0 0 0 8.83E+07 7.66E+07 - - - 4.8941 0.9996 221125_WJC_METTL3_EV_vs_WT_F07.07261.07261.3 0.0162 14/48 R.TGSAVAPVHPPNR[166.11].S "sp|Q8IZL8|PELP1_HUMAN,tr|I3L1P4|I3L1P4_HUMAN,tr|C9JFV4|C9JFV4_HUMAN,tr|I3L445|I3L445_HUMAN,tr|I3L4M7|I3L4M7_HUMAN" 5 1311.6923 5.98 95727 7261 3 1311.692852 438.238 "Proline-, glutamic acid- and leucine-rich protein 1 OS=Homo sapiens OX=9606 GN=PELP1 PE=1 SV=2" 9.44 1712.6 - 621703 - - - 0.4185 - 2.311 0.288 - 270.3 1 2 0 0.0005 13 0 0 0 1.96E+08 3.27E+07 - - - 4.022 1 221125_WJC_METTL3_EV_vs_WT_F07.07265.07265.2 1.58E-06 22-Dec K.VGGTSDVEVNEK[136.11].K "sp|P10809|CH60_HUMAN,tr|A0A7I2V2X6|A0A7I2V2X6_HUMAN,tr|A0A7I2YQK6|A0A7I2YQK6_HUMAN,tr|A0A7I2V599|A0A7I2V599_HUMAN" 4 1240.6027 1.38 95729 7265 2 1240.602069 621.3086 "60 kDa heat shock protein, mitochondrial OS=Homo sapiens OX=9606 GN=HSPD1 PE=1 SV=2" 4.14 1713.1 - 7.27E+06 - - - -0.4772 - 2.782 0.59 - 749 1 2 0 -0.0006 12 0 0 0 3.49E+08 2.53E+08 - - - 6.0907 0.9992 221125_WJC_METTL3_EV_vs_WT_F07.07269.07269.2 0.000846 14-Aug K.FQSFQDHK.L "sp|Q14331|FRG1_HUMAN,tr|E9PLY7|E9PLY7_HUMAN" 2 1035.4774 0.91 95731 7269 2 1035.478694 518.746 Protein FRG1 OS=Homo sapiens OX=9606 GN=FRG1 PE=1 SV=1 6.74 1713.5 - 498646 - - - 1.2555 - 1.302 0.423 - 169.4 1 2 0 0.0013 8 0 0 0 1.34E+07 1.47E+07 - - - 2.9608 0.9994 221125_WJC_METTL3_EV_vs_WT_F07.07270.07270.2 0.00404 18-Sep R.KAWENSPNVR.E "sp|Q9Y520|PRC2C_HUMAN,tr|E7EPN9|E7EPN9_HUMAN,tr|H7C5N8|H7C5N8_HUMAN,tr|A0A2R8Y7F4|A0A2R8Y7F4_HUMAN,tr|A0A2R8YET2|A0A2R8YET2_HUMAN" 5 1199.6047 0.4 95732 7270 2 1199.607164 600.8096 Protein PRRC2C OS=Homo sapiens OX=9606 GN=PRRC2C PE=1 SV=4 8.75 1713.6 - 399603 - - - 2.0373 - 1.804 0.413 - 355.8 1 2 0 0.0024 10 0 0 0 1.64E+07 4.11E+07 - - - 3.7375 0.9988 221125_WJC_METTL3_EV_vs_WT_F07.07276.07276.2 0.4 16-May K.DC[160.03]FTC[160.03]SNC[160.03]K[136.11].Q "sp|Q13642|FHL1_HUMAN,tr|Q5JXI2|Q5JXI2_HUMAN,tr|A0A0D9SFZ9|A0A0D9SFZ9_HUMAN,tr|A0A0D9SFI6|A0A0D9SFI6_HUMAN,tr|A0A494C0D6|A0A494C0D6_HUMAN,tr|Q5JXH7|Q5JXH7_HUMAN,tr|A0A0D9SGB2|A0A0D9SGB2_HUMAN,tr|Q5JXH9|Q5JXH9_HUMAN,tr|Q5JXI8|Q5JXI8_HUMAN,tr|A0A0D9SFB0|A0A0D9SFB0_HUMAN,tr|Q5JXI0|Q5JXI0_HUMAN,tr|Q5JXH8|Q5JXH8_HUMAN,tr|Q5JXI3|Q5JXI3_HUMAN" 13 1198.4297 0.72 95735 7276 2 1198.431767 600.2221 Four and a half LIM domains protein 1 OS=Homo sapiens OX=9606 GN=FHL1 PE=1 SV=4 5.82 1714.4 - 476281 - - - 1.754 - 1.21 0.437 - 62.4 1 2 0 0.0021 9 0 0 0 6.25E+06 8.74E+06 - - - 2.8195 0.9998 221125_WJC_METTL3_EV_vs_WT_F07.07278.07278.3 0.000425 13/36 R.ALHHGIDLEK[136.11].L "sp|P14868|SYDC_HUMAN,tr|H7BZ35|H7BZ35_HUMAN" 2 1139.6179 0.001 95737 7278 3 1139.617913 380.8799 "Aspartate--tRNA ligase, cytoplasmic OS=Homo sapiens OX=9606 GN=DARS1 PE=1 SV=2" 6 1714.6 - 4.34E+06 - - - 0.0491 - 1.845 0.391 - 138.3 1 2 0 0.0001 10 0 0 0 0.00E+00 9.87E+07 - - - 4.688 0.9996 221125_WJC_METTL3_EV_vs_WT_F07.07283.07283.3 1.80E-06 14/40 K.NSLTSK[136.11]DPDIK[136.11].A "sp|Q14974|IMB1_HUMAN,tr|J3QR48|J3QR48_HUMAN" 2 1232.6583 1.14 95740 7283 3 1232.65826 411.8934 Importin subunit beta-1 OS=Homo sapiens OX=9606 GN=KPNB1 PE=1 SV=2 5.96 1715.2 - 1.23E+07 - - - -0.0584 - 2.274 0.393 - 307.2 1 2 1 -0.0001 11 0 0 0 3.44E+08 3.01E+08 - - - 5.2554 0.9993 221125_WJC_METTL3_EV_vs_WT_F07.07285.07285.3 0.105 13/44 R.QVQSQAHGLQMR[166.11].L "sp|Q14683|SMC1A_HUMAN,tr|G8JLG1|G8JLG1_HUMAN,tr|A0A6Q8PHC3|A0A6Q8PHC3_HUMAN" 3 1391.6967 0.76 95742 7285 3 1391.69501 464.9062 Structural maintenance of chromosomes protein 1A OS=Homo sapiens OX=9606 GN=SMC1A PE=1 SV=2 9.76 1715.4 - 3.50E+06 - - - -1.2402 - 2.008 0.283 - 263.4 1 2 0 -0.0017 12 0 0 0 6.85E+07 9.00E+07 - - - 3.6271 0.9998 221125_WJC_METTL3_EV_vs_WT_F07.07286.07286.2 0.00154 22-Sep R.QVQSQAHGLQMR[166.11].L "sp|Q14683|SMC1A_HUMAN,tr|G8JLG1|G8JLG1_HUMAN,tr|A0A6Q8PHC3|A0A6Q8PHC3_HUMAN" 3 1391.6967 0.87 95743 7286 2 1391.69773 696.8556 Structural maintenance of chromosomes protein 1A OS=Homo sapiens OX=9606 GN=SMC1A PE=1 SV=2 9.76 1715.5 - 152229 - - - 0.7142 - 1.862 0.472 - 312.8 1 2 0 0.001 12 0 0 0 2.17E+06 2.51E+06 - - - 4.1625 0.9971 221125_WJC_METTL3_EV_vs_WT_F07.07287.07287.2 0.0511 26-Jul R.VEGTPSDPNPNDPR[166.11].A "sp|Q96IJ6|GMPPA_HUMAN,tr|A0A0U1RRC2|A0A0U1RRC2_HUMAN,tr|A0A804HIS0|A0A804HIS0_HUMAN" 3 1503.6829 1.02 95744 7287 2 1503.681117 752.8487 Mannose-1-phosphate guanyltransferase alpha OS=Homo sapiens OX=9606 GN=GMPPA PE=1 SV=1 4.03 1715.7 - 146202 - - - -1.1991 - 1.325 0.266 - 104.7 1 2 0 -0.0018 14 0 0 0 2.09E+07 2.05E+07 - - - 1.7113 0.9232 221125_WJC_METTL3_EV_vs_WT_F07.07291.07291.2 7.09E-06 18-Nov N.SLTSKDPDIK.A "sp|Q14974|IMB1_HUMAN,tr|J3QR48|J3QR48_HUMAN" 2 1102.587 1.28 95746 7291 2 1102.587004 552.3008 Importin subunit beta-1 OS=Homo sapiens OX=9606 GN=KPNB1 PE=1 SV=2 5.68 1716.2 - 441545 - - - 0 - 2.324 0.463 - 463.4 1 1 1 0 10 0 0 0 6.22E+06 4.87E+06 - - - 4.8146 0.9998 221125_WJC_METTL3_EV_vs_WT_F07.07299.07299.2 0.000104 18-Nov R.ALHHGIDLEK.L "sp|P14868|SYDC_HUMAN,tr|H7BZ35|H7BZ35_HUMAN" 2 1131.6037 0.89 95753 7299 2 1131.604464 566.8091 "Aspartate--tRNA ligase, cytoplasmic OS=Homo sapiens OX=9606 GN=DARS1 PE=1 SV=2" 6 1717 - 393506 - - - 0.7131 - 2.06 0.415 - 407 1 2 0 0.0008 10 0 0 0 5.82E+06 6.57E+06 - - - 4.1232 0.9993 221125_WJC_METTL3_EV_vs_WT_F07.07306.07306.2 0.00792 26-Aug R.VEGTPSDPNPNDPR.A "sp|Q96IJ6|GMPPA_HUMAN,tr|A0A0U1RRC2|A0A0U1RRC2_HUMAN,tr|A0A804HIS0|A0A804HIS0_HUMAN" 3 1493.6746 1.02 95759 7306 2 1493.677495 747.8446 Mannose-1-phosphate guanyltransferase alpha OS=Homo sapiens OX=9606 GN=GMPPA PE=1 SV=1 4.03 1717.8 - 212171 - - - 1.9047 - 1.707 0.419 - 115.9 1 2 0 0.0028 14 0 0 0 2.09E+07 2.05E+07 - - - 3.4767 0.9778 221125_WJC_METTL3_EV_vs_WT_F07.07311.07311.2 0.00285 18-Aug R.STSHK[136.11]PDEIY.G sp|Q86U44|MTA70_HUMAN 1 1183.5601 0.03 95762 7311 2 1183.560733 592.7873 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 5.3 1718.4 - 7.21E+06 - - - 0.5619 - 1.538 0.432 - 186.9 1 1 0 0.0007 10 0 0 0 6.17E+06 2.13E+08 - - - 3.4332 0.9958 221125_WJC_METTL3_EV_vs_WT_F07.07312.07312.2 0.000164 20-Nov K.NSLTSKDPDIK.A "sp|Q14974|IMB1_HUMAN,tr|J3QR48|J3QR48_HUMAN" 2 1216.6299 1.4 95763 7312 2 1216.630152 609.3222 Importin subunit beta-1 OS=Homo sapiens OX=9606 GN=KPNB1 PE=1 SV=2 5.96 1718.5 - 2.23E+06 - - - 0.1808 - 2.027 0.322 - 360 1 2 1 0.0002 11 0 0 0 6.21E+07 4.43E+07 - - - 3.3306 0.9977 221125_WJC_METTL3_EV_vs_WT_F07.07318.07318.2 0.0054 13/20 K.NSLTSK[136.11]DPDIK[136.11].A "sp|Q14974|IMB1_HUMAN,tr|J3QR48|J3QR48_HUMAN" 2 1232.6583 1.4 95767 7318 2 1232.65892 617.3364 Importin subunit beta-1 OS=Homo sapiens OX=9606 GN=KPNB1 PE=1 SV=2 5.96 1719.3 - 1.24E+06 - - - 0.477 - 2.384 0.376 - 627.3 1 2 1 0.0006 11 0 0 0 6.21E+07 4.43E+07 - - - 4.1682 0.9999 221125_WJC_METTL3_EV_vs_WT_F07.07320.07320.3 0.000315 15/48 R.TGSAVAPVHPPNR.S "sp|Q8IZL8|PELP1_HUMAN,tr|I3L1P4|I3L1P4_HUMAN,tr|C9JFV4|C9JFV4_HUMAN,tr|I3L445|I3L445_HUMAN,tr|I3L4M7|I3L4M7_HUMAN" 5 1301.684 3.42 95768 7320 3 1301.68451 434.902 "Proline-, glutamic acid- and leucine-rich protein 1 OS=Homo sapiens OX=9606 GN=PELP1 PE=1 SV=2" 9.44 1719.5 - 496354 - - - 0.3664 - 2.447 0.379 - 345.1 1 2 0 0.0005 13 0 0 0 9.78E+07 2.86E+07 - - - 5.1916 0.9996 221125_WJC_METTL3_EV_vs_WT_F07.07321.07321.2 0.00485 14-Sep R.KWQQLQAK.R "sp|Q6P2Q9|PRP8_HUMAN,tr|I3L0J9|I3L0J9_HUMAN" 2 1028.5767 1.77 95769 7321 2 1028.577412 515.2956 Pre-mRNA-processing-splicing factor 8 OS=Homo sapiens OX=9606 GN=PRPF8 PE=1 SV=2 10 1719.6 - 465118 - - - 0.6786 - 1.848 0.358 - 320.1 1 2 0 0.0007 8 0 0 0 1.91E+07 1.08E+07 - - - 3.5371 0.9997 221125_WJC_METTL3_EV_vs_WT_F07.07330.07330.3 0.0649 Dec-52 R.GLSGPSGPGHMASR[166.11].G sp|Q14151|SAFB2_HUMAN 1 1319.628 1.46 95774 7330 3 1319.62991 440.8833 Scaffold attachment factor B2 OS=Homo sapiens OX=9606 GN=SAFB2 PE=1 SV=1 9.76 1720.8 - 201823 - - - 1.4565 - 2.093 0.353 - 128.6 1 2 0 0.0019 14 0 0 0 7.79E+06 5.32E+06 - - - 4.4379 0.9852 221125_WJC_METTL3_EV_vs_WT_F07.07332.07332.2 0.0355 18-Jun K.QQQLPDGTGR[166.11].D sp|O15020|SPTN2_HUMAN 1 1108.5501 1 95776 7332 2 1108.555001 555.2823 "Spectrin beta chain, non-erythrocytic 2 OS=Homo sapiens OX=9606 GN=SPTBN2 PE=1 SV=3" 5.84 1721 - 137067 - - - 4.4617 - 1.45 0.297 - 147.6 1 2 0 0.0049 10 0 0 0 4.45E+06 4.46E+06 - - - 2.2702 1 221125_WJC_METTL3_EV_vs_WT_F07.07334.07334.2 1.80E-07 26-Dec K.FQGSGAATETAESR[166.11].R "sp|O15047|SET1A_HUMAN,tr|A0A804HLA6|A0A804HLA6_HUMAN" 2 1420.6458 1.41 95778 7334 2 1420.64437 711.3302 Histone-lysine N-methyltransferase SETD1A OS=Homo sapiens OX=9606 GN=SETD1A PE=1 SV=3 4.53 1721.3 - 68718.5 - - - -1.0108 - 2.264 0.642 - 393.2 1 2 0 -0.0014 14 0 0 0 1.06E+07 7.55E+06 - - - 5.8329 1 221125_WJC_METTL3_EV_vs_WT_F07.07339.07339.2 1.05E-07 13/20 R.HAAC[160.03]PVLVGNK.W sp|P13674|P4HA1_HUMAN 1 1164.6074 1.29 95781 7339 2 1164.613099 583.311 Prolyl 4-hydroxylase subunit alpha-1 OS=Homo sapiens OX=9606 GN=P4HA1 PE=1 SV=2 8.23 1722 - 256818 - - - 4.9253 - 2.557 0.605 - 454.1 1 2 0 0.0057 11 0 0 0 1.51E+07 1.17E+07 - - - 6.0475 1 221125_WJC_METTL3_EV_vs_WT_F07.07340.07340.2 8.28E-09 13/26 K.FQGSGAATETAESR.R "sp|O15047|SET1A_HUMAN,tr|A0A804HLA6|A0A804HLA6_HUMAN" 2 1410.6375 1.41 95782 7340 2 1410.637939 706.326 Histone-lysine N-methyltransferase SETD1A OS=Homo sapiens OX=9606 GN=SETD1A PE=1 SV=3 4.53 1722.1 - 218810 - - - 0.2857 - 2.728 0.706 - 420 1 2 0 0.0004 14 0 0 0 1.06E+07 7.55E+06 - - - 6.7738 0.9995 221125_WJC_METTL3_EV_vs_WT_F07.07341.07341.2 0.000114 22-Aug K.C[160.03]EDLETQTQSEK[136.11].Q sp|O00592|PODXL_HUMAN 1 1474.6337 1.28 95783 7341 2 1474.638111 738.3241 Podocalyxin OS=Homo sapiens OX=9606 GN=PODXL PE=1 SV=2 4 1722.2 - 115001 - - - 2.9892 - 1.931 0.586 - 205.5 1 2 0 0.0044 12 0 0 0 3.29E+06 2.57E+06 - - - 5.0992 0.9989 221125_WJC_METTL3_EV_vs_WT_F07.07342.07342.2 0.000182 28-Sep K.TTTAAAVASTGPSSR.S "sp|P27816|MAP4_HUMAN,tr|H0Y2V1|H0Y2V1_HUMAN,tr|E7EVA0|E7EVA0_HUMAN,tr|F8W9U4|F8W9U4_HUMAN,tr|H7C4C5|H7C4C5_HUMAN,tr|A0A804HKE7|A0A804HKE7_HUMAN,tr|B5MEG9|B5MEG9_HUMAN" 7 1376.6896 0.53 95784 7342 2 1376.693441 689.3521 Microtubule-associated protein 4 OS=Homo sapiens OX=9606 GN=MAP4 PE=1 SV=3 9.41 1722.4 - 107945 - - - 2.8104 - 1.606 0.473 - 274.5 1 2 0 0.0039 15 0 0 0 7.73E+06 1.45E+07 - - - 3.6981 0.9996 221125_WJC_METTL3_EV_vs_WT_F07.07346.07346.2 0.00208 14-Oct R.K[136.11]WQQLQAK[136.11].R "sp|Q6P2Q9|PRP8_HUMAN,tr|I3L0J9|I3L0J9_HUMAN" 2 1044.6051 1.77 95786 7346 2 1044.606183 523.3098 Pre-mRNA-processing-splicing factor 8 OS=Homo sapiens OX=9606 GN=PRPF8 PE=1 SV=2 10 1722.9 - 723267 - - - 1.0234 - 1.781 0.364 - 240.2 1 2 0 0.0011 8 0 0 0 1.91E+07 1.08E+07 - - - 3.4699 1 221125_WJC_METTL3_EV_vs_WT_F07.07348.07348.2 5.39E-08 14/20 R.HAAC[160.03]PVLVGNK[136.11].W sp|P13674|P4HA1_HUMAN 1 1172.6216 1.31 95788 7348 2 1172.625412 587.3181 Prolyl 4-hydroxylase subunit alpha-1 OS=Homo sapiens OX=9606 GN=P4HA1 PE=1 SV=2 8.23 1723.1 - 333343 - - - 3.2824 - 2.801 0.573 - 604.8 1 2 0 0.0038 11 0 0 0 1.51E+07 1.15E+07 - - - 6.0583 0.8011 221125_WJC_METTL3_EV_vs_WT_F07.07354.07354.3 0.61 Jul-44 R.EGPDLDRPGSDR.Q "sp|Q7Z4V5|HDGR2_HUMAN,tr|A0A087WZ99|A0A087WZ99_HUMAN" 2 1312.6008 0.94 95791 7354 3 1312.603371 438.5409 Hepatoma-derived growth factor-related protein 2 OS=Homo sapiens OX=9606 GN=HDGFL2 PE=1 SV=1 4.23 1723.8 - 681271 - - - 1.9915 - 1.575 0.051 - 98.3 1 2 0 0.0026 12 0 0 0 1.22E+07 1.30E+07 - - - 0.367 0.9896 221125_WJC_METTL3_EV_vs_WT_F07.07356.07356.3 0.404 Oct-40 R.R[166.11]LGELPADHPK[136.11].G sp|Q16512|PKN1_HUMAN 1 1249.6898 8.1 95793 7356 3 1249.691146 417.5705 Serine\threonine-protein kinase N1 OS=Homo sapiens OX=9606 GN=PKN1 PE=1 SV=2 6.75 1724 - 967398 - - - 1.0851 - 2 0.122 - 179 1 2 0 0.0014 11 0 0 0 4.89E+07 6.03E+06 - - - 1.8689 0.9997 221125_WJC_METTL3_EV_vs_WT_F07.07362.07362.3 0.000932 Oct-40 R.HAAC[160.03]PVLVGNK.W sp|P13674|P4HA1_HUMAN 1 1164.6074 1.66 95797 7362 3 1164.608972 389.2097 Prolyl 4-hydroxylase subunit alpha-1 OS=Homo sapiens OX=9606 GN=P4HA1 PE=1 SV=2 8.23 1724.8 - 881457 - - - 1.3816 - 2.11 0.333 - 128.7 1 2 0 0.0016 11 0 0 0 2.03E+07 1.23E+07 - - - 4.3734 0.9981 221125_WJC_METTL3_EV_vs_WT_F07.07364.07364.2 0.00654 16-Sep K.ENLPISGHK.H sp|P20930|FILA_HUMAN 1 993.5243 0.11 95799 7364 2 993.526684 497.7694 Filaggrin OS=Homo sapiens OX=9606 GN=FLG PE=1 SV=3 6.85 1725 - 1.23E+06 - - - 2.3553 - 1.726 0.291 - 339 1 2 0 0.0023 9 0 0 0 2.22E+07 2.03E+08 - - - 2.7686 0.9987 221125_WJC_METTL3_EV_vs_WT_F07.07365.07365.3 0.00815 Sep-40 R.HAAC[160.03]PVLVGNK[136.11].W sp|P13674|P4HA1_HUMAN 1 1172.6216 1.69 95800 7365 3 1172.623428 391.8811 Prolyl 4-hydroxylase subunit alpha-1 OS=Homo sapiens OX=9606 GN=P4HA1 PE=1 SV=2 8.23 1725.1 - 632485 - - - 1.5905 - 1.98 0.264 - 138 1 2 0 0.0019 11 0 0 0 2.07E+07 1.23E+07 - - - 3.4234 0.9975 221125_WJC_METTL3_EV_vs_WT_F07.07366.07366.3 0.00914 Nov-40 K.QVHEIQSC[160.03]MGR.L "sp|O14653|GOSR2_HUMAN,tr|I3NI02|I3NI02_HUMAN,tr|E7EQ34|E7EQ34_HUMAN,tr|A0A1W2PPP5|A0A1W2PPP5_HUMAN,tr|A0A1W2PPG5|A0A1W2PPG5_HUMAN,tr|I3L0K1|I3L0K1_HUMAN,tr|A0A1W2PR23|A0A1W2PR23_HUMAN,tr|A0A1W2PRC2|A0A1W2PRC2_HUMAN,tr|A0A1W2PRP7|A0A1W2PRP7_HUMAN,tr|A0A1W2PR02|A0A1W2PR02_HUMAN,tr|A0A1X7SBU8|A0A1X7SBU8_HUMAN,tr|A0A1W2PS81|A0A1W2PS81_HUMAN,tr|I3L4Z6|I3L4Z6_HUMAN,tr|A0A1W2PQ77|A0A1W2PQ77_HUMAN,tr|A0A1W2PPJ0|A0A1W2PPJ0_HUMAN,tr|A0A1W2PPG1|A0A1W2PPG1_HUMAN,tr|A0A1W2PRV0|A0A1W2PRV0_HUMAN,tr|A0A1W2PQ06|A0A1W2PQ06_HUMAN,tr|A0A1W2PPW8|A0A1W2PPW8_HUMAN,tr|A0A1W2PQM3|A0A1W2PQM3_HUMAN,tr|I3L1K7|I3L1K7_HUMAN" 21 1343.6074 0.95 95801 7366 3 1343.607081 448.8764 Golgi SNAP receptor complex member 2 OS=Homo sapiens OX=9606 GN=GOSR2 PE=1 SV=2 6.74 1725.2 - 349202 - - - -0.2664 - 1.654 0.244 - 172.3 1 2 0 -0.0004 11 0 0 0 7.28E+06 7.66E+06 - - - 2.6898 1 221125_WJC_METTL3_EV_vs_WT_F07.07368.07368.2 4.86E-08 22-Nov K.VDC[160.03]QAYAQTC[160.03]QK.A "sp|Q8IXB1|DJC10_HUMAN,tr|A0A7P0Z431|A0A7P0Z431_HUMAN,tr|A0A7P0TB97|A0A7P0TB97_HUMAN,tr|A0A7P0TAQ9|A0A7P0TAQ9_HUMAN" 4 1470.6231 0.89 95803 7368 2 1470.625895 736.3189 DnaJ homolog subfamily C member 10 OS=Homo sapiens OX=9606 GN=DNAJC10 PE=1 SV=2 5.79 1725.4 - 216437 - - - 1.8672 - 2.279 0.644 - 565.2 1 2 0 0.0027 12 0 0 0 4.18E+06 4.69E+06 - - - 5.9641 0.9926 221125_WJC_METTL3_EV_vs_WT_F07.07369.07369.3 0.000268 Nov-52 R.ALAAPAAEEKEEAR.E sp|Q01650|LAT1_HUMAN 1 1454.7365 1.22 95804 7369 3 1454.743192 485.9195 Large neutral amino acids transporter small subunit 1 OS=Homo sapiens OX=9606 GN=SLC7A5 PE=1 SV=2 4.49 1725.6 - 147785 - - - 4.585 - 2.144 0.392 - 163.8 1 2 1 0.0067 14 0 0 0 2.69E+06 2.20E+06 - - - 4.9354 0.9986 221125_WJC_METTL3_EV_vs_WT_F07.07370.07370.2 0.000874 20-Aug K.VEETTEHLVTK.S "sp|P52732|KIF11_HUMAN,tr|A0A7I2V3A9|A0A7I2V3A9_HUMAN" 2 1284.6561 0.21 95805 7370 2 1284.659988 643.3353 Kinesin-like protein KIF11 OS=Homo sapiens OX=9606 GN=KIF11 PE=1 SV=2 4.75 1725.7 - 72184.6 - - - 2.9907 - 1.715 0.413 - 119.4 1 2 0 0.0038 11 0 0 0 5.72E+05 2.67E+06 - - - 3.5495 0.9666 221125_WJC_METTL3_EV_vs_WT_F07.07371.07371.2 0.287 20-May R.QNQIPTEDGSR[166.11].V "sp|Q86TU7|SETD3_HUMAN,tr|Q6NXR6|Q6NXR6_HUMAN" 2 1253.5876 0.11 95806 7371 2 1253.590786 627.8011 Actin-histidine N-methyltransferase OS=Homo sapiens OX=9606 GN=SETD3 PE=1 SV=1 4.37 1725.8 - 60777.3 - - - 2.571 - 0.974 0.223 - 83.5 1 2 0 0.0032 11 0 0 0 6.68E+04 6.00E+05 - - - 0.6158 0.9977 221125_WJC_METTL3_EV_vs_WT_F07.07377.07377.3 0.00736 Nov-48 R.ELQHAALGGTATR[166.11].Q sp|O14828|SCAM3_HUMAN 1 1333.6978 1.18 95810 7377 3 1333.700521 445.5732 Secretory carrier-associated membrane protein 3 OS=Homo sapiens OX=9606 GN=SCAMP3 PE=1 SV=3 6.85 1726.5 - 628470 - - - 2.0537 - 1.973 0.253 - 134.1 1 2 0 0.0027 13 0 0 0 7.29E+06 6.18E+06 - - - 3.2024 0.9955 221125_WJC_METTL3_EV_vs_WT_F07.07378.07378.2 1.78E-06 15/28 K.TTTAAAVASTGPSSR[166.11].S "sp|P27816|MAP4_HUMAN,tr|H0Y2V1|H0Y2V1_HUMAN,tr|E7EVA0|E7EVA0_HUMAN,tr|F8W9U4|F8W9U4_HUMAN,tr|H7C4C5|H7C4C5_HUMAN,tr|A0A804HKE7|A0A804HKE7_HUMAN,tr|B5MEG9|B5MEG9_HUMAN" 7 1386.6978 0.53 95811 7378 2 1386.706163 694.3562 Microtubule-associated protein 4 OS=Homo sapiens OX=9606 GN=MAP4 PE=1 SV=3 9.41 1726.6 - 447319 - - - 6.0006 - 2.621 0.477 - 651.2 1 2 0 0.0083 15 0 0 0 7.73E+06 1.45E+07 - - - 4.9305 0.9963 221125_WJC_METTL3_EV_vs_WT_F07.07383.07383.2 2.45E-05 24-Aug K.STNTSQTGLVGTK[136.11].H sp|Q96R06|SPAG5_HUMAN 1 1300.6714 1.42 95816 7383 2 1300.677809 651.343 Sperm-associated antigen 5 OS=Homo sapiens OX=9606 GN=SPAG5 PE=1 SV=2 8.47 1727.2 - 178459 - - - 4.9205 - 1.854 0.471 - 208.6 1 2 0 0.0064 13 0 0 0 3.76E+06 2.65E+06 - - - 4.1022 0.9986 221125_WJC_METTL3_EV_vs_WT_F07.07386.07386.2 0.000104 30-Sep R.ASAAEGVGEPGASAGR[166.11].A "tr|A0A7I2V3I7|A0A7I2V3I7_HUMAN,tr|A0A7I2YQQ9|A0A7I2YQQ9_HUMAN,tr|A0A499FIZ0|A0A499FIZ0_HUMAN" 3 1395.6618 3.4 95819 7386 2 1395.666889 698.8382 WD repeat-containing protein 26 OS=Homo sapiens OX=9606 GN=WDR26 PE=1 SV=1 4.53 1727.6 - 116938 - - - 3.6527 - 1.738 0.509 - 201.5 1 2 0 0.0051 16 0 0 0 8.68E+06 2.55E+06 - - - 4.1578 0.9972 221125_WJC_METTL3_EV_vs_WT_F07.07393.07393.2 0.000288 18-Nov R.NRGPPPSWGR.R sp|P84103|SRSF3_HUMAN 1 1122.5683 1.23 95824 7393 2 1122.57061 562.2914 Serine\arginine-rich splicing factor 3 OS=Homo sapiens OX=9606 GN=SRSF3 PE=1 SV=1 12 1728.4 - 509037 - - - 2.0801 - 2.339 0.514 - 195.5 1 2 1 0.0023 10 0 0 0 1.38E+07 1.12E+07 - - - 5.2085 0.9989 221125_WJC_METTL3_EV_vs_WT_F07.07394.07394.2 0.0121 18-Sep K.RVDELQQQVK.L sp|Q8TBA6|GOGA5_HUMAN 1 1241.6728 1.85 95825 7394 2 1241.675063 621.8437 Golgin subfamily A member 5 OS=Homo sapiens OX=9606 GN=GOLGA5 PE=1 SV=3 6.07 1728.6 - 467913 - - - 1.8225 - 1.957 0.282 - 240.7 1 2 0 0.0023 10 0 0 0 4.62E+06 2.50E+06 - - - 2.9973 0.9995 221125_WJC_METTL3_EV_vs_WT_F07.07395.07395.3 5.59E-05 Oct-48 R.IPGVNK[136.11]EEETESR[166.11].E sp|O60318|GANP_HUMAN 1 1504.7488 1.8 95826 7395 3 1504.750956 502.5902 Germinal-center associated nuclear protein OS=Homo sapiens OX=9606 GN=MCM3AP PE=1 SV=2 4.49 1728.7 - 446255 - - - 1.4188 - 1.773 0.477 - 88.9 1 2 1 0.0021 13 0 0 0 1.30E+07 7.24E+06 - - - 5.4102 0.961 221125_WJC_METTL3_EV_vs_WT_F07.07396.07396.2 0.000699 18-Oct R.NR[166.11]GPPPSWGR[166.11].R sp|P84103|SRSF3_HUMAN 1 1142.5848 1.23 95827 7396 2 1142.588318 572.2997 Serine\arginine-rich splicing factor 3 OS=Homo sapiens OX=9606 GN=SRSF3 PE=1 SV=1 12 1728.8 - 382039 - - - 3.0659 - 2.065 0.212 - 156 1 2 1 0.0035 10 0 0 0 1.42E+07 1.15E+07 - - - 2.6298 0.9999 221125_WJC_METTL3_EV_vs_WT_F07.07398.07398.2 8.78E-06 22-Oct K.VDC[160.03]QAYAQTC[160.03]QK[136.11].A "sp|Q8IXB1|DJC10_HUMAN,tr|A0A7P0Z431|A0A7P0Z431_HUMAN,tr|A0A7P0TB97|A0A7P0TB97_HUMAN,tr|A0A7P0TAQ9|A0A7P0TAQ9_HUMAN" 4 1478.6373 0.89 95829 7398 2 1478.637502 740.326 DnaJ homolog subfamily C member 10 OS=Homo sapiens OX=9606 GN=DNAJC10 PE=1 SV=2 5.79 1729.1 - 291176 - - - 0.1035 - 1.898 0.619 - 424.5 1 2 0 0.0002 12 0 0 0 4.18E+06 4.69E+06 - - - 5.2989 0.996 221125_WJC_METTL3_EV_vs_WT_F07.07406.07406.3 0.000625 Nov-44 K.GK[136.11]GGEIQPVSVK[136.11].V "sp|P61604|CH10_HUMAN,tr|B8ZZL8|B8ZZL8_HUMAN" 2 1213.7001 1.01 95835 7406 3 1213.703457 405.574 "10 kDa heat shock protein, mitochondrial OS=Homo sapiens OX=9606 GN=HSPE1 PE=1 SV=2" 8.59 1729.9 - 833445 - - - 2.7354 - 1.95 0.35 - 145 1 2 1 0.0033 12 0 0 0 3.90E+07 3.88E+07 - - - 4.2924 0.9825 221125_WJC_METTL3_EV_vs_WT_F07.07407.07407.3 0.00598 Sep-44 K.GKGGEIQPVSVK.V "sp|P61604|CH10_HUMAN,tr|B8ZZL8|B8ZZL8_HUMAN" 2 1197.6717 0.91 95836 7407 3 1197.673622 400.2312 "10 kDa heat shock protein, mitochondrial OS=Homo sapiens OX=9606 GN=HSPE1 PE=1 SV=2" 8.59 1730 - 732321 - - - 1.5739 - 1.63 0.248 - 87.9 1 2 1 0.0019 12 0 0 0 3.32E+07 3.63E+07 - - - 2.6587 0.996 221125_WJC_METTL3_EV_vs_WT_F07.07418.07418.3 0.087 13/36 R.NR[166.11]GPPPSWGR[166.11].R sp|P84103|SRSF3_HUMAN 1 1142.5848 0.001 95845 7418 3 1142.585401 381.8689 Serine\arginine-rich splicing factor 3 OS=Homo sapiens OX=9606 GN=SRSF3 PE=1 SV=1 12 1731.3 - 1.97E+06 - - - 0.5129 - 2.674 0.179 - 252.7 1 2 1 0.0006 10 0 0 0 0.00E+00 3.94E+07 - - - 3.408 0.9999 221125_WJC_METTL3_EV_vs_WT_F07.07419.07419.3 0.000436 Sep-44 K.HLIPAANTGESK.V sp|P62258|1433E_HUMAN 1 1236.6463 1.14 95846 7419 3 1236.647132 413.2227 14-3-3 protein epsilon OS=Homo sapiens OX=9606 GN=YWHAE PE=1 SV=1 6.75 1731.4 - 913129 - - - 0.7132 - 1.726 0.469 - 130.1 1 2 0 0.0009 12 0 0 0 1.14E+08 1.00E+08 - - - 5.2815 0.9996 221125_WJC_METTL3_EV_vs_WT_F07.07421.07421.2 7.34E-07 22-Aug R.GSSSANPVNSVR.R "sp|Q99661|KIF2C_HUMAN,tr|Q5JR89|Q5JR89_HUMAN" 2 1173.5738 1.71 95848 7421 2 1173.576163 587.7942 Kinesin-like protein KIF2C OS=Homo sapiens OX=9606 GN=KIF2C PE=1 SV=2 9.75 1731.7 - 588032 - - - 2.0016 - 1.806 0.498 - 171.1 1 2 0 0.0023 12 0 0 0 1.63E+07 9.53E+06 - - - 4.2738 0.9992 221125_WJC_METTL3_EV_vs_WT_F07.07424.07424.3 0.0151 Sep-44 K.VMSQNFTNC[160.03]HTK[136.11].L "sp|Q13283|G3BP1_HUMAN,tr|A0A7I2YQB1|A0A7I2YQB1_HUMAN,tr|A0A7I2V5M7|A0A7I2V5M7_HUMAN,tr|E5RH42|E5RH42_HUMAN,tr|A0A7I2V533|A0A7I2V533_HUMAN,tr|A0A7P0P2U7|A0A7P0P2U7_HUMAN,tr|A0A7I2V2S5|A0A7I2V2S5_HUMAN,tr|A0A7I2YQU8|A0A7I2YQU8_HUMAN,tr|E5RJU8|E5RJU8_HUMAN,tr|A0A7I2YQQ8|A0A7I2YQQ8_HUMAN,tr|A0A7I2V651|A0A7I2V651_HUMAN,tr|E5RIF8|E5RIF8_HUMAN,tr|A0A7I2YQN9|A0A7I2YQN9_HUMAN" 13 1473.6584 1.17 95851 7424 3 1473.658088 492.2267 Ras GTPase-activating protein-binding protein 1 OS=Homo sapiens OX=9606 GN=G3BP1 PE=1 SV=1 8.2 1732 - 430995 - - - -0.2246 - 1.911 0.284 - 93.8 1 2 0 -0.0003 12 0 0 0 1.81E+07 1.54E+07 - - - 3.5014 0.9999 221125_WJC_METTL3_EV_vs_WT_F07.07425.07425.3 0.00447 Aug-44 K.VMSQNFTNC[160.03]HTK.L "sp|Q13283|G3BP1_HUMAN,tr|A0A7I2YQB1|A0A7I2YQB1_HUMAN,tr|A0A7I2V5M7|A0A7I2V5M7_HUMAN,tr|E5RH42|E5RH42_HUMAN,tr|A0A7I2V533|A0A7I2V533_HUMAN,tr|A0A7P0P2U7|A0A7P0P2U7_HUMAN,tr|A0A7I2V2S5|A0A7I2V2S5_HUMAN,tr|A0A7I2YQU8|A0A7I2YQU8_HUMAN,tr|E5RJU8|E5RJU8_HUMAN,tr|A0A7I2YQQ8|A0A7I2YQQ8_HUMAN,tr|A0A7I2V651|A0A7I2V651_HUMAN,tr|E5RIF8|E5RIF8_HUMAN,tr|A0A7I2YQN9|A0A7I2YQN9_HUMAN" 13 1465.6442 1.12 95852 7425 3 1465.644292 489.5553 Ras GTPase-activating protein-binding protein 1 OS=Homo sapiens OX=9606 GN=G3BP1 PE=1 SV=1 8.2 1732.2 - 360151 - - - 0.0498 - 1.747 0.452 - 75.6 1 2 0 0.0001 12 0 0 0 1.65E+07 1.47E+07 - - - 5.1257 0.9996 221125_WJC_METTL3_EV_vs_WT_F07.07433.07433.2 0.000164 20-Oct K.C[160.03]NTC[160.03]GEPITDR.M "sp|Q15942|ZYX_HUMAN,tr|H0Y2Y8|H0Y2Y8_HUMAN,tr|C9JJK5|C9JJK5_HUMAN" 3 1321.5391 3.3 95857 7433 2 1321.54299 661.7768 Zyxin OS=Homo sapiens OX=9606 GN=ZYX PE=1 SV=1 4.37 1733.2 - 2.22E+06 - - - 2.9549 - 1.659 0.671 - 313 1 2 0 0.0039 11 0 0 0 2.66E+07 8.04E+06 - - - 5.3652 0.9958 221125_WJC_METTL3_EV_vs_WT_F07.07435.07435.3 0.0776 Sep-36 K.K[136.11]SLDQDPVVR[166.11].A "sp|Q92598|HS105_HUMAN,tr|Q5TBM3|Q5TBM3_HUMAN,tr|A0A0A0MSM0|A0A0A0MSM0_HUMAN" 3 1173.6473 0.62 95859 7435 3 1173.650189 392.223 Heat shock protein 105 kDa OS=Homo sapiens OX=9606 GN=HSPH1 PE=1 SV=1 5.96 1733.4 - 513669 - - - 2.4982 - 1.911 0.231 - 146.3 1 2 0 0.0029 10 0 0 0 5.09E+06 8.16E+06 - - - 3.006 0.9999 221125_WJC_METTL3_EV_vs_WT_F07.07437.07437.3 2.07E-05 Nov-48 K.R[166.11]PAMLDNEADGNK[136.11].T "sp|Q93009|UBP7_HUMAN,tr|A0A669KBL1|A0A669KBL1_HUMAN,tr|H3BND8|H3BND8_HUMAN" 3 1447.6844 1.43 95861 7437 3 1447.682917 483.5688 Ubiquitin carboxyl-terminal hydrolase 7 OS=Homo sapiens OX=9606 GN=USP7 PE=1 SV=2 4.56 1733.7 - 196314 - - - -1.0569 - 2.031 0.484 - 199.5 1 2 0 -0.0015 13 0 0 0 3.03E+06 2.12E+06 - - - 5.8567 0.9999 221125_WJC_METTL3_EV_vs_WT_F07.07442.07442.2 4.83E-07 18-Nov K.DANGNSFATR[166.11].L "sp|P62701|RS4X_HUMAN,sp|P22090|RS4Y1_HUMAN,sp|Q8TD47|RS4Y2_HUMAN,tr|C9JEH7|C9JEH7_HUMAN" 4 1061.4766 1.12 95864 7442 2 1061.476689 531.7456 "40S ribosomal protein S4, X isoform OS=Homo sapiens OX=9606 GN=RPS4X PE=1 SV=2" 5.84 1734.3 - 515550 - - - 0.1253 - 2.071 0.565 - 483.8 1 2 0 0.0001 10 0 0 0 1.34E+07 1.19E+07 - - - 5.2462 0.9999 221125_WJC_METTL3_EV_vs_WT_F07.07443.07443.2 9.69E-07 18-Sep K.DANGNSFATR.L "sp|P62701|RS4X_HUMAN,sp|P22090|RS4Y1_HUMAN,sp|Q8TD47|RS4Y2_HUMAN,tr|C9JEH7|C9JEH7_HUMAN" 4 1051.4683 1.04 95865 7443 2 1051.468232 526.7414 "40S ribosomal protein S4, X isoform OS=Homo sapiens OX=9606 GN=RPS4X PE=1 SV=2" 5.84 1734.4 - 527485 - - - -0.0514 - 1.949 0.546 - 365.6 1 2 0 -0.0001 10 0 0 0 1.34E+07 1.29E+07 - - - 4.9364 0.7883 221125_WJC_METTL3_EV_vs_WT_F07.07447.07447.2 0.161 24-Feb K.REEGSDIEDEDME.E "sp|Q8NHQ9|DDX55_HUMAN,tr|F5H5U2|F5H5U2_HUMAN" 2 1552.5835 1.72 95869 7447 2 1552.582897 777.299 ATP-dependent RNA helicase DDX55 OS=Homo sapiens OX=9606 GN=DDX55 PE=1 SV=3 3.77 1735 - 152466 - - - -0.3955 - 0.866 0.402 - 5.4 10 1 0 -0.0006 13 0 0 0 6.52E+07 3.80E+07 - - - 1.194 0.999 221125_WJC_METTL3_EV_vs_WT_F07.07450.07450.3 0.164 Nov-44 K.KEVELAPGASDR.V "sp|P22735|TGM1_HUMAN,tr|H0YMQ8|H0YMQ8_HUMAN" 2 1270.6517 2.05 95870 7450 3 1270.650946 424.5579 Protein-glutamine gamma-glutamyltransferase K OS=Homo sapiens OX=9606 GN=TGM1 PE=1 SV=4 4.68 1735.4 - 1.26E+06 - - - -0.617 - 2.092 0.247 - 223.9 1 2 0 -0.0008 12 0 0 0 2.39E+07 1.17E+07 - - - 3.3396 0.9998 221125_WJC_METTL3_EV_vs_WT_F07.07453.07453.2 2.87E-05 20-Aug K.ENAGEDPGLAR.Q sp|P81605|DCD_HUMAN 1 1127.5207 999 95873 7453 2 1127.518983 564.7676 Dermcidin OS=Homo sapiens OX=9606 GN=DCD PE=1 SV=2 4.14 1735.7 - 605618 - - - -1.537 - 1.987 0.546 - 144.6 1 2 0 -0.0017 11 0 0 0 1.33E+07 0.00E+00 - - - 4.9307 0.9998 221125_WJC_METTL3_EV_vs_WT_F07.07454.07454.2 0.000207 20-Jul K.C[160.03]NTC[160.03]GEPITDR[166.11].M "sp|Q15942|ZYX_HUMAN,tr|H0Y2Y8|H0Y2Y8_HUMAN,tr|C9JJK5|C9JJK5_HUMAN" 3 1331.5474 3.34 95874 7454 2 1331.545846 666.781 Zyxin OS=Homo sapiens OX=9606 GN=ZYX PE=1 SV=1 4.37 1735.9 - 410574 - - - -1.1333 - 1.86 0.484 - 189.8 1 2 0 -0.0015 11 0 0 0 2.89E+07 8.66E+06 - - - 4.2942 0.9967 221125_WJC_METTL3_EV_vs_WT_F07.07455.07455.2 0.0114 18-Aug R.ADILEDKDGK.S "sp|P52272|HNRPM_HUMAN,tr|M0R019|M0R019_HUMAN,tr|M0R0N3|M0R0N3_HUMAN,tr|A0A087X0X3|A0A087X0X3_HUMAN,tr|M0QZM1|M0QZM1_HUMAN,tr|M0QYQ7|M0QYQ7_HUMAN,tr|M0R2T0|M0R2T0_HUMAN" 7 1102.5506 2.06 95875 7455 2 1102.550641 552.2826 Heterogeneous nuclear ribonucleoprotein M OS=Homo sapiens OX=9606 GN=HNRNPM PE=1 SV=3 4.23 1736 - 287057 - - - 0.02 - 1.982 0.356 - 185 1 2 1 0 10 0 0 0 2.41E+07 1.17E+07 - - - 3.58 0.9998 221125_WJC_METTL3_EV_vs_WT_F07.07459.07459.2 0.000465 24-Oct R.YSTSGSSGLTTGK.L "sp|Q16891|MIC60_HUMAN,tr|B9A067|B9A067_HUMAN,tr|A0A087WYS0|A0A087WYS0_HUMAN,tr|D6RAW4|D6RAW4_HUMAN" 4 1244.5885 1.18 95877 7459 2 1244.588436 623.3015 MICOS complex subunit MIC60 OS=Homo sapiens OX=9606 GN=IMMT PE=1 SV=1 8.59 1736.4 - 3.51E+06 - - - -0.0201 - 1.798 0.475 - 241.1 1 2 0 0 13 0 0 0 3.56E+08 3.02E+08 - - - 4.0551 0.9983 221125_WJC_METTL3_EV_vs_WT_F07.07462.07462.2 0.0251 20-Jul K.SSPVPVSDTQK[136.11].L "sp|Q76FK4|NOL8_HUMAN,tr|F5GWN9|F5GWN9_HUMAN,tr|F5H101|F5H101_HUMAN,tr|F8WE42|F8WE42_HUMAN" 4 1151.5914 2.27 95880 7462 2 1151.590821 576.803 Nucleolar protein 8 OS=Homo sapiens OX=9606 GN=NOL8 PE=1 SV=1 5.55 1736.8 - 198304 - - - -0.475 - 1.144 0.341 - 120.2 1 2 0 -0.0005 11 0 0 0 7.99E+06 3.52E+06 - - - 1.9234 0.9994 221125_WJC_METTL3_EV_vs_WT_F07.07467.07467.3 0.00717 13/32 R.R[166.11]R[166.11]EEEMMIR[166.11].Q "sp|P23246|SFPQ_HUMAN,tr|H0Y9K7|H0Y9K7_HUMAN" 2 1278.6315 0.33 95883 7467 3 1278.631717 427.2178 "Splicing factor, proline- and glutamine-rich OS=Homo sapiens OX=9606 GN=SFPQ PE=1 SV=2" 6.23 1737.4 - 1.15E+06 - - - 0.1533 - 1.833 0.417 - 248.6 1 2 1 0.0002 9 0 0 0 1.18E+07 3.63E+07 - - - 5.0153 0.9974 221125_WJC_METTL3_EV_vs_WT_F07.07477.07477.2 0.000132 18-Sep R.ADILEDK[136.11]DGK[136.11].S "sp|P52272|HNRPM_HUMAN,tr|M0R019|M0R019_HUMAN,tr|M0R0N3|M0R0N3_HUMAN,tr|A0A087X0X3|A0A087X0X3_HUMAN,tr|M0QZM1|M0QZM1_HUMAN,tr|M0QYQ7|M0QYQ7_HUMAN,tr|M0R2T0|M0R2T0_HUMAN" 7 1118.579 2.16 95891 7477 2 1118.580172 560.2968 Heterogeneous nuclear ribonucleoprotein M OS=Homo sapiens OX=9606 GN=HNRNPM PE=1 SV=3 4.23 1738.7 - 409143 - - - 1.0308 - 2.047 0.44 - 241.1 1 2 1 0.0012 10 0 0 0 2.40E+07 1.11E+07 - - - 4.2901 1 221125_WJC_METTL3_EV_vs_WT_F07.07481.07481.3 2.42E-06 13/44 K.HLIPAANTGESK[136.11].V sp|P62258|1433E_HUMAN 1 1244.6605 1.15 95893 7481 3 1244.660682 415.8941 14-3-3 protein epsilon OS=Homo sapiens OX=9606 GN=YWHAE PE=1 SV=1 6.75 1739.2 - 4.52E+06 - - - 0.1864 - 2.436 0.584 - 259.4 1 2 0 0.0002 12 0 0 0 1.16E+08 1.00E+08 - - - 7.5189 0.9961 221125_WJC_METTL3_EV_vs_WT_F07.07486.07486.2 0.017 18-Jun R.IVGHLTHALK.Q "sp|P24752|THIL_HUMAN,tr|A0A5F9ZHD4|A0A5F9ZHD4_HUMAN,tr|A0A5F9ZHJ0|A0A5F9ZHJ0_HUMAN,tr|A0A5F9ZHL1|A0A5F9ZHL1_HUMAN,tr|A0A5F9ZI66|A0A5F9ZI66_HUMAN" 5 1087.6502 1.37 95898 7486 2 1087.651284 544.8324 "Acetyl-CoA acetyltransferase, mitochondrial OS=Homo sapiens OX=9606 GN=ACAT1 PE=1 SV=1" 8.76 1739.7 - 297952 - - - 0.9838 - 1.257 0.262 - 83.6 2 2 0 0.0011 10 0 0 0 3.82E+06 2.78E+06 - - - 1.4798 0.9999 221125_WJC_METTL3_EV_vs_WT_F07.07487.07487.2 0.000511 24-Oct R.GGGEQETQELASK[136.11].R sp|Q96QR8|PURB_HUMAN 1 1340.6299 1.42 95899 7487 2 1340.629278 671.3222 Transcriptional activator protein Pur-beta OS=Homo sapiens OX=9606 GN=PURB PE=1 SV=3 4.25 1739.9 - 211936 - - - -0.4923 - 2.322 0.527 - 370.7 1 2 0 -0.0007 13 0 0 0 1.42E+07 9.94E+06 - - - 5.0953 0.9914 221125_WJC_METTL3_EV_vs_WT_F07.07488.07488.2 2.63E-05 14-Jul R.EQDKYYYR.Y "sp|Q16875|F263_HUMAN,tr|A0A1W2PR17|A0A1W2PR17_HUMAN,tr|Q5W015|Q5W015_HUMAN,tr|F2Z2I2|F2Z2I2_HUMAN,tr|Q5VX20|Q5VX20_HUMAN" 5 1163.5247 5.51 95900 7488 2 1163.523904 582.7696 "6-phosphofructo-2-kinase\fructose-2,6-bisphosphatase 3 OS=Homo sapiens OX=9606 GN=PFKFB3 PE=1 SV=1" 6.17 1740 - 206254 - - - -0.7168 - 1.743 0.265 - 296.3 1 2 1 -0.0008 8 0 0 0 1.09E+07 1.99E+06 - - - 2.6737 0.998 221125_WJC_METTL3_EV_vs_WT_F07.07489.07489.2 1.06E-08 28-Dec R.VPQDVTQGPGATGGK.E sp|Q8N0Y2|ZN444_HUMAN 1 1410.7103 1.24 95901 7489 2 1410.71762 706.3624 Zinc finger protein 444 OS=Homo sapiens OX=9606 GN=ZNF444 PE=1 SV=1 5.81 1740.1 - 158468 - - - 5.1839 - 2.416 0.579 - 233.1 1 2 0 0.0073 15 0 0 0 2.43E+07 1.96E+07 - - - 5.4839 0.9999 221125_WJC_METTL3_EV_vs_WT_F07.07491.07491.2 9.76E-05 20-Dec K.DSYVGDEAQSK.R "sp|P63261|ACTG_HUMAN,sp|P68133|ACTS_HUMAN,sp|P62736|ACTA_HUMAN,sp|P68032|ACTC_HUMAN,sp|P60709|ACTB_HUMAN,sp|P63267|ACTH_HUMAN,tr|A0A804GS07|A0A804GS07_HUMAN,tr|I3L3I0|I3L3I0_HUMAN,tr|G5E9R0|G5E9R0_HUMAN,tr|E7EVS6|E7EVS6_HUMAN,tr|A0A6Q8PFE4|A0A6Q8PFE4_HUMAN,tr|B8ZZJ2|B8ZZJ2_HUMAN,tr|J3KT65|J3KT65_HUMAN,tr|I3L3R2|I3L3R2_HUMAN,tr|K7EM38|K7EM38_HUMAN,tr|F6QUT6|F6QUT6_HUMAN,tr|C9JTX5|C9JTX5_HUMAN,tr|A0A6Q8PH58|A0A6Q8PH58_HUMAN,tr|F6UVQ4|F6UVQ4_HUMAN,tr|F8WB63|F8WB63_HUMAN,tr|I3L1U9|I3L1U9_HUMAN,tr|A0A804HKV3|A0A804HKV3_HUMAN,tr|A0A2R8Y793|A0A2R8Y793_HUMAN,tr|I3L4N8|I3L4N8_HUMAN,tr|C9JUM1|C9JUM1_HUMAN,tr|C9JZR7|C9JZR7_HUMAN,tr|C9JFL5|C9JFL5_HUMAN,tr|A0A2R8YGF8|A0A2R8YGF8_HUMAN,tr|A6NL76|A6NL76_HUMAN" 29 1197.515 1.01 95902 7491 2 1197.516223 599.7648 "Actin, cytoplasmic 2 OS=Homo sapiens OX=9606 GN=ACTG1 PE=1 SV=1" 4.03 1740.4 - 7.21E+06 - - - 1.0538 - 2.215 0.589 - 303.4 1 2 0 0.0013 11 0 0 0 9.48E+08 9.35E+08 - - - 5.5423 0.9999 221125_WJC_METTL3_EV_vs_WT_F07.07495.07495.2 1.65E-05 13/24 R.GGGEQETQELASK.R sp|Q96QR8|PURB_HUMAN 1 1332.6157 1.41 95906 7495 2 1332.617206 667.3151 Transcriptional activator protein Pur-beta OS=Homo sapiens OX=9606 GN=PURB PE=1 SV=3 4.25 1740.9 - 584793 - - - 1.1016 - 2.459 0.506 - 637.2 1 2 0 0.0015 13 0 0 0 1.42E+07 1.00E+07 - - - 5.0871 1 221125_WJC_METTL3_EV_vs_WT_F07.07503.07503.2 1.10E-08 15/24 K.STVNC[160.03]STTPVAER[166.11].F "sp|Q99567|NUP88_HUMAN,tr|J3KMX1|J3KMX1_HUMAN,tr|I3L245|I3L245_HUMAN" 3 1430.6699 1.76 95912 7503 2 1430.671958 716.3422 Nuclear pore complex protein Nup88 OS=Homo sapiens OX=9606 GN=NUP88 PE=1 SV=2 5.72 1742 - 765058 - - - 1.4294 - 2.79 0.649 - 1067.4 1 2 0 0.002 13 0 0 0 3.72E+07 2.11E+07 - - - 6.4672 0.9891 221125_WJC_METTL3_EV_vs_WT_F07.07505.07505.2 0.00024 15/18 V.KVDPEIQNVK.A sp|P35908|K22E_HUMAN 1 1168.6452 999 95914 7505 2 1168.646214 585.3299 "Keratin, type II cytoskeletal 2 epidermal OS=Homo sapiens OX=9606 GN=KRT2 PE=1 SV=2" 6.07 1742.2 - 675214 - - - 0.8779 - 2.715 0.367 - 791.8 1 1 0 0.001 10 0 0 0 3.22E+07 0.00E+00 - - - 4.5393 0.9997 221125_WJC_METTL3_EV_vs_WT_F07.07513.07513.3 0.00227 Dec-36 R.SGLNQIPNRR.F "sp|Q6P2Q9|PRP8_HUMAN,tr|I3L3Z8|I3L3Z8_HUMAN" 2 1153.6316 1.21 95919 7513 3 1153.633771 385.5511 Pre-mRNA-processing-splicing factor 8 OS=Homo sapiens OX=9606 GN=PRPF8 PE=1 SV=2 12 1743.2 - 1.13E+06 - - - 1.8793 - 2.243 0.343 - 252 1 2 0 0.0022 10 0 0 0 1.06E+08 8.79E+07 - - - 4.7227 0.9551 221125_WJC_METTL3_EV_vs_WT_F07.07516.07516.2 0.000416 20-Nov K.DSSLGLSKEDK.A sp|O00443|P3C2A_HUMAN 1 1177.5826 1.47 95922 7516 2 1177.587066 589.7986 Phosphatidylinositol 4-phosphate 3-kinase C2 domain-containing subunit alpha OS=Homo sapiens OX=9606 GN=PIK3C2A PE=1 SV=2 4.56 1743.6 - 358246 - - - 3.7526 - 1.619 0.356 - 326.8 1 2 1 0.0044 11 0 0 0 4.05E+06 2.76E+06 - - - 2.9724 0.9998 221125_WJC_METTL3_EV_vs_WT_F07.07517.07517.3 7.89E-06 Dec-52 R.IREDEGAVASSTVK.E "sp|Q9P0U4|CXXC1_HUMAN,tr|K7EQZ1|K7EQZ1_HUMAN,tr|K7EQ21|K7EQ21_HUMAN,tr|K7EKZ6|K7EKZ6_HUMAN,tr|A0A669KB29|A0A669KB29_HUMAN" 5 1460.7471 1.39 95923 7517 3 1460.746313 487.923 CXXC-type zinc finger protein 1 OS=Homo sapiens OX=9606 GN=CXXC1 PE=1 SV=2 4.68 1743.7 - 348867 - - - -0.5299 - 2.513 0.465 - 258.3 1 2 1 -0.0008 14 0 0 0 6.73E+06 4.86E+06 - - - 6.1729 0.9999 221125_WJC_METTL3_EV_vs_WT_F07.07525.07525.2 0.0132 24-Sep K.EDIYSGGGGGGSR.S sp|Q13151|ROA0_HUMAN 1 1210.5214 1.47 95928 7525 2 1210.521146 606.268 Heterogeneous nuclear ribonucleoprotein A0 OS=Homo sapiens OX=9606 GN=HNRNPA0 PE=1 SV=1 4.37 1744.7 - 505233 - - - -0.2462 - 2.102 0.512 - 246.8 1 2 0 -0.0003 13 0 0 0 1.09E+08 7.40E+07 - - - 4.7292 0.9991 221125_WJC_METTL3_EV_vs_WT_F07.07526.07526.3 0.0314 Sep-44 K.LVPTHTQVPVHR[166.11].R sp|Q96RF0|SNX18_HUMAN 1 1392.7865 0.72 95929 7526 3 1392.789242 465.2695 Sorting nexin-18 OS=Homo sapiens OX=9606 GN=SNX18 PE=1 SV=2 9.76 1744.8 - 416964 - - - 1.9414 - 2.025 0.298 - 91.8 1 2 0 0.0027 12 0 0 0 4.06E+06 5.67E+06 - - - 3.8174 0.9152 221125_WJC_METTL3_EV_vs_WT_F07.07527.07527.2 0.0484 24-Jun H.NTPYGTASEPSEK.A sp|Q9NXV2|KCTD5_HUMAN 1 1379.6205 20.94 95930 7527 2 1379.620658 690.8175 BTB\POZ domain-containing protein KCTD5 OS=Homo sapiens OX=9606 GN=KCTD5 PE=1 SV=1 4.53 1744.9 - 246856 - - - 0.1225 - 1.314 0.307 - 44.9 1 1 0 0.0002 13 0 0 0 1.37E+07 6.56E+05 - - - 2.0093 0.9999 221125_WJC_METTL3_EV_vs_WT_F07.07531.07531.2 0.000144 18-Oct K.NC[160.03]TYTQVQTR.S "sp|P23193|TCEA1_HUMAN,sp|Q15560|TCEA2_HUMAN,tr|B7Z4S1|B7Z4S1_HUMAN,tr|A0A0A0MT58|A0A0A0MT58_HUMAN,tr|A0A1W2PRL9|A0A1W2PRL9_HUMAN,tr|A0A1W2PPZ5|A0A1W2PPZ5_HUMAN" 6 1269.5772 1.13 95932 7531 2 1269.576259 635.7959 Transcription elongation factor A protein 1 OS=Homo sapiens OX=9606 GN=TCEA1 PE=1 SV=2 8.22 1745.5 - 523827 - - - -0.7294 - 2.052 0.505 - 503.7 1 2 0 -0.0009 10 0 0 0 3.84E+07 3.39E+07 - - - 4.7771 0.9999 221125_WJC_METTL3_EV_vs_WT_F07.07532.07532.2 8.02E-07 18-Oct K.NC[160.03]TYTQVQTR[166.11].S "sp|P23193|TCEA1_HUMAN,sp|Q15560|TCEA2_HUMAN,tr|B7Z4S1|B7Z4S1_HUMAN,tr|A0A0A0MT58|A0A0A0MT58_HUMAN,tr|A0A1W2PRL9|A0A1W2PRL9_HUMAN,tr|A0A1W2PPZ5|A0A1W2PPZ5_HUMAN" 6 1279.5855 1.13 95933 7532 2 1279.586817 640.8 Transcription elongation factor A protein 1 OS=Homo sapiens OX=9606 GN=TCEA1 PE=1 SV=2 8.22 1745.6 - 597264 - - - 1.0644 - 2.303 0.546 - 541.7 1 2 0 0.0014 10 0 0 0 3.84E+07 3.39E+07 - - - 5.4019 1 221125_WJC_METTL3_EV_vs_WT_F07.07535.07535.3 0.000684 14/40 R.KVVGC[160.03]SC[160.03]VVVK.D sp|P25398|RS12_HUMAN 1 1233.6573 0.96 95934 7535 3 1233.656424 412.2264 40S ribosomal protein S12 OS=Homo sapiens OX=9606 GN=RPS12 PE=1 SV=3 8.9 1746 - 3.21E+06 - - - -0.7506 - 3.003 0.458 - 429.7 1 2 0 -0.0009 11 0 0 0 4.79E+07 4.97E+07 - - - 6.7698 0.9992 221125_WJC_METTL3_EV_vs_WT_F07.07537.07537.3 0.002 Jul-40 R.GC[160.03]SNQYLVTHK.Q sp|Q96L58|B3GT6_HUMAN 1 1305.6136 0.63 95936 7537 3 1305.613863 436.2118 "Beta-1,3-galactosyltransferase 6 OS=Homo sapiens OX=9606 GN=B3GALT6 PE=1 SV=2" 8.21 1746.2 - 1.16E+06 - - - 0.2244 - 1.57 0.329 - 49.4 1 2 0 0.0003 11 0 0 0 2.37E+07 3.79E+07 - - - 3.4894 1 221125_WJC_METTL3_EV_vs_WT_F07.07543.07543.2 5.52E-07 24-Nov K.EDIYSGGGGGGSR[166.11].S sp|Q13151|ROA0_HUMAN 1 1220.5297 1.47 95940 7543 2 1220.527879 611.2721 Heterogeneous nuclear ribonucleoprotein A0 OS=Homo sapiens OX=9606 GN=HNRNPA0 PE=1 SV=1 4.37 1747 - 2.08E+06 - - - -1.5034 - 2.448 0.636 - 327.3 1 2 0 -0.0018 13 0 0 0 1.09E+08 7.40E+07 - - - 6.0357 0.9999 221125_WJC_METTL3_EV_vs_WT_F07.07544.07544.2 3.84E-07 18-Dec R.K[136.11]IGDTSVSYK[136.11].Y sp|P20700|LMNB1_HUMAN 1 1112.6048 1.2 95941 7544 2 1112.60455 557.3097 Lamin-B1 OS=Homo sapiens OX=9606 GN=LMNB1 PE=1 SV=2 8.5 1747.1 - 558567 - - - -0.2606 - 2.322 0.583 - 416.8 1 2 0 -0.0003 10 0 0 0 1.85E+07 1.54E+07 - - - 5.6984 0.9979 221125_WJC_METTL3_EV_vs_WT_F07.07545.07545.2 0.00587 20-Jul R.GC[160.03]SNQYLVTHK[136.11].Q sp|Q96L58|B3GT6_HUMAN 1 1313.6278 0.37 95942 7545 2 1313.628837 657.8212 "Beta-1,3-galactosyltransferase 6 OS=Homo sapiens OX=9606 GN=B3GALT6 PE=1 SV=2" 8.21 1747.2 - 236045 - - - 0.8123 - 1.418 0.262 - 124.9 1 2 0 0.0011 11 0 0 0 2.06E+06 5.53E+06 - - - 1.9206 0.9996 221125_WJC_METTL3_EV_vs_WT_F07.07554.07554.2 0.000455 20-Jul R.GC[160.03]SNQYLVTHK.Q sp|Q96L58|B3GT6_HUMAN 1 1305.6136 0.35 95949 7554 2 1305.612786 653.8141 "Beta-1,3-galactosyltransferase 6 OS=Homo sapiens OX=9606 GN=B3GALT6 PE=1 SV=2" 8.21 1748.4 - 184255 - - - -0.6005 - 1.387 0.452 - 196 1 2 0 -0.0008 11 0 0 0 2.06E+06 5.81E+06 - - - 3.2642 0.9998 221125_WJC_METTL3_EV_vs_WT_F07.07557.07557.3 0.00136 Sep-44 K.ALEHSALAINHK[136.11].L "sp|P17812|PYRG1_HUMAN,sp|Q9NRF8|PYRG2_HUMAN,tr|A0A3B3ITF6|A0A3B3ITF6_HUMAN,tr|B4E1E0|B4E1E0_HUMAN,tr|A0A3B3IRQ8|A0A3B3IRQ8_HUMAN,tr|A0A3B3ITB8|A0A3B3ITB8_HUMAN,tr|A0A3B3IRI2|A0A3B3IRI2_HUMAN,tr|A0A3B3ISY3|A0A3B3ISY3_HUMAN" 8 1310.7186 0.9 95950 7557 3 1310.71813 437.9135 CTP synthase 1 OS=Homo sapiens OX=9606 GN=CTPS1 PE=1 SV=2 6.96 1748.8 - 1.75E+06 - - - -0.3845 - 1.932 0.376 - 103 1 2 0 -0.0005 12 0 0 0 2.64E+07 2.95E+07 - - - 4.5573 0.9998 221125_WJC_METTL3_EV_vs_WT_F07.07561.07561.2 7.99E-07 26-Sep R.STGSATSLASQGER[166.11].R "sp|Q5SW79|CE170_HUMAN,tr|H0Y2V6|H0Y2V6_HUMAN" 2 1360.6458 1.05 95954 7561 2 1360.643085 681.3302 Centrosomal protein of 170 kDa OS=Homo sapiens OX=9606 GN=CEP170 PE=1 SV=1 5.72 1749.2 - 198168 - - - -1.9998 - 2.238 0.579 - 238.3 1 2 0 -0.0027 14 0 0 0 1.10E+07 1.05E+07 - - - 5.3382 0.9454 221125_WJC_METTL3_EV_vs_WT_F07.07564.07564.3 0.721 Sep-40 R.ESAINVAEGK[136.11]K[136.11].Q "sp|Q9UJZ1|STML2_HUMAN,tr|A0A087WYB4|A0A087WYB4_HUMAN,tr|F2Z2I8|F2Z2I8_HUMAN" 3 1160.6372 1.32 95955 7564 3 1160.636881 387.8863 "Stomatin-like protein 2, mitochondrial OS=Homo sapiens OX=9606 GN=STOML2 PE=1 SV=1" 6.24 1749.6 - 1.09E+06 - - - -0.2766 - 1.499 0.1 - 74.5 1 2 0 -0.0003 11 0 0 0 1.02E+08 7.70E+07 - - - 0.8048 1 221125_WJC_METTL3_EV_vs_WT_F07.07565.07565.3 0.000133 14/52 R.NVIHASDSVEGAQR.E "sp|O00746|NDKM_HUMAN,tr|Q4TT34|Q4TT34_HUMAN,tr|A0A087WVT9|A0A087WVT9_HUMAN,tr|F2Z2X0|F2Z2X0_HUMAN" 4 1481.7223 1.16 95956 7565 3 1481.721581 494.9147 "Nucleoside diphosphate kinase, mitochondrial OS=Homo sapiens OX=9606 GN=NME4 PE=1 SV=1" 5.32 1749.6 - 1.04E+06 - - - -0.4643 - 2.433 0.546 - 218.8 1 2 0 -0.0007 14 0 0 0 4.76E+07 4.11E+07 - - - 6.99 0.9998 221125_WJC_METTL3_EV_vs_WT_F07.07566.07566.3 0.00187 Oct-40 K.TGSNSFTVHPR[166.11].G sp|Q4KMQ1|TPRN_HUMAN 1 1211.5923 1.12 95957 7566 3 1211.59219 404.8714 Taperin OS=Homo sapiens OX=9606 GN=TPRN PE=1 SV=2 9.44 1749.7 - 1.27E+06 - - - -0.0528 - 2.116 0.347 - 173.3 1 2 0 -0.0001 11 0 0 0 5.19E+07 4.62E+07 - - - 4.538 1 221125_WJC_METTL3_EV_vs_WT_F07.07567.07567.2 7.52E-09 15/28 R.VPQDVTQGPGATGGK[136.11].E sp|Q8N0Y2|ZN444_HUMAN 1 1418.7245 1.24 95958 7567 2 1418.724344 710.3695 Zinc finger protein 444 OS=Homo sapiens OX=9606 GN=ZNF444 PE=1 SV=1 5.81 1749.8 - 569538 - - - -0.1149 - 2.684 0.625 - 904.8 1 2 0 -0.0002 15 0 0 0 2.43E+07 1.96E+07 - - - 6.0845 0.9862 221125_WJC_METTL3_EV_vs_WT_F07.07568.07568.3 6.90E-06 15/56 L.LVQAGADVDAADNRK.L "sp|O75179|ANR17_HUMAN,sp|Q8IWZ3|ANKH1_HUMAN,tr|E9PDP5|E9PDP5_HUMAN,tr|H0YM23|H0YM23_HUMAN,tr|H3BLS9|H3BLS9_HUMAN,tr|H0YLQ3|H0YLQ3_HUMAN,tr|H7C2F5|H7C2F5_HUMAN" 7 1541.7798 1.53 95959 7568 3 1541.784789 514.9339 Ankyrin repeat domain-containing protein 17 OS=Homo sapiens OX=9606 GN=ANKRD17 PE=1 SV=3 4.43 1750 - 355158 - - - 3.2462 - 2.648 0.491 - 261.8 1 1 0 0.005 15 0 0 0 8.66E+06 5.67E+06 - - - 6.5538 0.9853 221125_WJC_METTL3_EV_vs_WT_F07.07569.07569.3 0.000134 Dec-56 L.LVQAGADVDAADNR[166.11]K[136.11].L "sp|O75179|ANR17_HUMAN,sp|Q8IWZ3|ANKH1_HUMAN,tr|E9PDP5|E9PDP5_HUMAN,tr|H0YM23|H0YM23_HUMAN,tr|H3BLS9|H3BLS9_HUMAN,tr|H0YLQ3|H0YLQ3_HUMAN,tr|H7C2F5|H7C2F5_HUMAN" 7 1559.8023 1.53 95960 7569 3 1559.800476 520.9414 Ankyrin repeat domain-containing protein 17 OS=Homo sapiens OX=9606 GN=ANKRD17 PE=1 SV=3 4.43 1750.1 - 290637 - - - -1.1399 - 2.232 0.385 - 157.3 1 1 0 -0.0018 15 0 0 0 8.66E+06 5.67E+06 - - - 4.9269 1 221125_WJC_METTL3_EV_vs_WT_F07.07571.07571.3 1.30E-06 14/44 K.ALEHSALAINHK.L "sp|P17812|PYRG1_HUMAN,sp|Q9NRF8|PYRG2_HUMAN,tr|A0A3B3ITF6|A0A3B3ITF6_HUMAN,tr|B4E1E0|B4E1E0_HUMAN,tr|A0A3B3IRQ8|A0A3B3IRQ8_HUMAN,tr|A0A3B3ITB8|A0A3B3ITB8_HUMAN,tr|A0A3B3IRI2|A0A3B3IRI2_HUMAN,tr|A0A3B3ISY3|A0A3B3ISY3_HUMAN" 8 1302.7044 0.89 95961 7571 3 1302.703673 435.2421 CTP synthase 1 OS=Homo sapiens OX=9606 GN=CTPS1 PE=1 SV=2 6.96 1750.3 - 1.59E+06 - - - -0.5842 - 2.709 0.463 - 289.9 1 2 0 -0.0008 12 0 0 0 2.62E+07 2.95E+07 - - - 6.4642 1 221125_WJC_METTL3_EV_vs_WT_F07.07574.07574.3 2.73E-05 13/40 R.RGGPNYQEGLR.V "sp|P53396|ACLY_HUMAN,tr|K7EIE7|K7EIE7_HUMAN" 2 1245.6214 0.59 95963 7574 3 1245.620212 416.2144 ATP-citrate synthase OS=Homo sapiens OX=9606 GN=ACLY PE=1 SV=3 8.75 1750.6 - 1.08E+06 - - - -0.9802 - 2.329 0.474 - 296.9 1 2 0 -0.0012 11 0 0 0 1.65E+07 2.79E+07 - - - 6.226 0.9999 221125_WJC_METTL3_EV_vs_WT_F07.07576.07576.2 0.00925 16/26 R.STGSATSLASQGER.R "sp|Q5SW79|CE170_HUMAN,tr|H0Y2V6|H0Y2V6_HUMAN" 2 1350.6375 1.05 95965 7576 2 1350.637186 676.326 Centrosomal protein of 170 kDa OS=Homo sapiens OX=9606 GN=CEP170 PE=1 SV=1 5.72 1750.8 - 608765 - - - -0.2591 - 2.99 0.525 - 1148.9 1 2 0 -0.0004 14 0 0 0 1.10E+07 1.05E+07 - - - 5.6671 1 221125_WJC_METTL3_EV_vs_WT_F07.07578.07578.2 1.16E-06 14/24 K.GGPAEGQLQENDR.V "sp|Q07157|ZO1_HUMAN,tr|A0A087X0K9|A0A087X0K9_HUMAN,tr|G5E9E7|G5E9E7_HUMAN,tr|A0A0G2JNH2|A0A0G2JNH2_HUMAN,tr|H0YKB1|H0YKB1_HUMAN,tr|G3V1L9|G3V1L9_HUMAN,tr|A0A7I2V5U5|A0A7I2V5U5_HUMAN" 7 1369.6222 0.7 95967 7578 2 1369.623592 685.8184 Tight junction protein ZO-1 OS=Homo sapiens OX=9606 GN=TJP1 PE=1 SV=3 4.14 1751.1 - 415911 - - - 1.001 - 2.856 0.603 - 787.5 1 2 0 0.0014 13 0 0 0 8.41E+06 1.20E+07 - - - 6.1877 0.9998 221125_WJC_METTL3_EV_vs_WT_F07.07583.07583.3 0.0323 Oct-40 R.R[166.11]GGPNYQEGLR[166.11].V "sp|P53396|ACLY_HUMAN,tr|K7EIE7|K7EIE7_HUMAN" 2 1265.638 0.61 95970 7583 3 1265.637711 422.8866 ATP-citrate synthase OS=Homo sapiens OX=9606 GN=ACLY PE=1 SV=3 8.75 1751.7 - 1.94E+06 - - - -0.207 - 2.069 0.344 - 133.5 1 2 0 -0.0003 11 0 0 0 1.65E+07 2.70E+07 - - - 4.4407 0.9967 221125_WJC_METTL3_EV_vs_WT_F07.07585.07585.2 0.0152 18-Sep K.QDTVELQNQK.S sp|Q5VT06|CE350_HUMAN 1 1201.5939 2.34 95972 7585 2 1201.591271 601.8042 Centrosome-associated protein 350 OS=Homo sapiens OX=9606 GN=CEP350 PE=1 SV=1 4.37 1751.9 - 1.24E+06 - - - -2.1721 - 1.739 0.206 - 287.3 1 2 0 -0.0026 10 0 0 0 2.87E+07 1.23E+07 - - - 2.1062 0.9997 221125_WJC_METTL3_EV_vs_WT_F07.07586.07586.2 0.000671 20-Oct R.ESAINVAEGK[136.11]K[136.11].Q "sp|Q9UJZ1|STML2_HUMAN,tr|A0A087WYB4|A0A087WYB4_HUMAN,tr|F2Z2I8|F2Z2I8_HUMAN" 3 1160.6372 1.46 95973 7586 2 1160.638539 581.3259 "Stomatin-like protein 2, mitochondrial OS=Homo sapiens OX=9606 GN=STOML2 PE=1 SV=1" 6.24 1752 - 537116 - - - 1.152 - 2.04 0.398 - 360.4 1 2 0 0.0013 11 0 0 0 2.04E+07 1.40E+07 - - - 3.9089 1 221125_WJC_METTL3_EV_vs_WT_F07.07587.07587.2 2.35E-07 20-Nov K.ADTSQEIC[160.03]SPR.L "sp|P52948|NUP98_HUMAN,tr|A0A3B3ITD8|A0A3B3ITD8_HUMAN,tr|H7C3P6|H7C3P6_HUMAN" 3 1262.5561 0.62 95974 7587 2 1262.557579 632.2853 Nuclear pore complex protein Nup98-Nup96 OS=Homo sapiens OX=9606 GN=NUP98 PE=1 SV=4 4.37 1752.2 - 448658 - - - 1.1596 - 2.487 0.608 - 738.9 1 2 0 0.0015 11 0 0 0 2.07E+07 3.37E+07 - - - 5.9959 1 221125_WJC_METTL3_EV_vs_WT_F07.07588.07588.2 3.46E-09 26-Dec R.NVIHASDSVEGAQR.E "sp|O00746|NDKM_HUMAN,tr|Q4TT34|Q4TT34_HUMAN,tr|A0A087WVT9|A0A087WVT9_HUMAN,tr|F2Z2X0|F2Z2X0_HUMAN" 4 1481.7223 1.79 95975 7588 2 1481.726479 741.8684 "Nucleoside diphosphate kinase, mitochondrial OS=Homo sapiens OX=9606 GN=NME4 PE=1 SV=1" 5.32 1752.3 - 315472 - - - 2.8413 - 2.514 0.675 - 510.3 1 2 0 0.0042 14 0 0 0 5.15E+06 2.89E+06 - - - 6.3386 0.9987 221125_WJC_METTL3_EV_vs_WT_F07.07593.07593.3 8.61E-06 Dec-52 R.NVIHASDSVEGAQR[166.11].E "sp|O00746|NDKM_HUMAN,tr|Q4TT34|Q4TT34_HUMAN,tr|A0A087WVT9|A0A087WVT9_HUMAN,tr|F2Z2X0|F2Z2X0_HUMAN" 4 1491.7305 1.16 95978 7593 3 1492.732668 498.2508 "Nucleoside diphosphate kinase, mitochondrial OS=Homo sapiens OX=9606 GN=NME4 PE=1 SV=1" 5.32 1752.9 - 1.40E+06 - - - 671.7896 - 2.302 0.494 - 208.7 1 2 0 1.0021 14 0 0 0 4.76E+07 4.11E+07 - - - 5.9858 0.9953 221125_WJC_METTL3_EV_vs_WT_F07.07594.07594.3 0.00655 Sep-44 K.LK[136.11]GELESSDQVR[166.11].E "sp|Q9P2E9|RRBP1_HUMAN,tr|A0A087WU26|A0A087WU26_HUMAN,tr|A0A087WVV2|A0A087WVV2_HUMAN,tr|F8W7S5|F8W7S5_HUMAN" 4 1377.7219 0.19 95979 7594 3 1377.722051 460.2479 Ribosome-binding protein 1 OS=Homo sapiens OX=9606 GN=RRBP1 PE=1 SV=5 4.68 1753 - 869093 - - - 0.1256 - 1.944 0.261 - 152.4 1 2 1 0.0002 12 0 0 0 2.08E+06 1.12E+07 - - - 3.2924 0.9993 221125_WJC_METTL3_EV_vs_WT_F07.07596.07596.3 0.00353 Oct-48 R.EFGNPNRPVASTR.L sp|Q9UJK0|TSR3_HUMAN 1 1443.7219 1.29 95981 7596 3 1443.72289 482.2479 18S rRNA aminocarboxypropyltransferase OS=Homo sapiens OX=9606 GN=TSR3 PE=1 SV=1 9.7 1753.2 - 504776 - - - 0.703 - 1.729 0.318 - 110.2 1 2 0 0.001 13 0 0 0 1.54E+07 1.20E+07 - - - 3.5697 0.993 221125_WJC_METTL3_EV_vs_WT_F07.07598.07598.2 0.000247 22-Nov L.QAAAQSLNVQSK.S "sp|P14859|PO2F1_HUMAN,tr|A0A0A0MT46|A0A0A0MT46_HUMAN" 2 1243.6521 2.05 95983 7598 2 1243.653226 622.8333 "POU domain, class 2, transcription factor 1 OS=Homo sapiens OX=9606 GN=POU2F1 PE=1 SV=2" 8.75 1753.4 - 291420 - - - 0.9343 - 2.626 0.519 - 464.4 1 1 0 0.0012 12 0 0 0 5.85E+06 2.86E+06 - - - 5.4143 0.9993 221125_WJC_METTL3_EV_vs_WT_F07.07600.07600.2 0.000262 26-May R.LGPSTGSTAETQC[160.03]R.N "sp|Q5T200|ZC3HD_HUMAN,tr|A0A7I2V4I5|A0A7I2V4I5_HUMAN" 2 1463.6675 0.53 95985 7600 2 1463.667879 732.841 Zinc finger CCCH domain-containing protein 13 OS=Homo sapiens OX=9606 GN=ZC3H13 PE=1 SV=1 5.99 1753.7 - 80468.8 - - - 0.289 - 1.224 0.426 - 39 1 2 0 0.0004 14 0 0 0 2.03E+06 3.85E+06 - - - 2.6945 0.9996 221125_WJC_METTL3_EV_vs_WT_F07.07605.07605.3 2.44E-05 Dec-48 R.EFGNPNR[166.11]PVASTR[166.11].L sp|Q9UJK0|TSR3_HUMAN 1 1463.7384 1.57 95988 7605 3 1463.741766 488.9201 18S rRNA aminocarboxypropyltransferase OS=Homo sapiens OX=9606 GN=TSR3 PE=1 SV=1 9.7 1754.4 - 700976 - - - 2.2893 - 1.76 0.41 - 167 1 2 0 0.0034 13 0 0 0 1.92E+07 1.22E+07 - - - 4.6429 0.9975 221125_WJC_METTL3_EV_vs_WT_F07.07607.07607.3 0.000131 Dec-48 R.VC[160.03]DATYDK[136.11]APVEK[136.11].E "sp|Q12974|TP4A2_HUMAN,tr|E9PRR9|E9PRR9_HUMAN,tr|E9PMY3|E9PMY3_HUMAN,tr|E9PJC0|E9PJC0_HUMAN,tr|E9PML8|E9PML8_HUMAN" 5 1510.7308 0.97 95990 7607 3 1510.725565 504.5842 Protein tyrosine phosphatase type IVA 2 OS=Homo sapiens OX=9606 GN=PTP4A2 PE=1 SV=1 4.56 1754.6 - 303186 - - - -3.495 - 2.097 0.415 - 196.4 1 2 1 -0.0053 13 0 0 0 8.80E+06 9.08E+06 - - - 5.1731 0.9997 221125_WJC_METTL3_EV_vs_WT_F07.07610.07610.2 0.000191 26-Sep R.NVIHASDSVEGAQR[166.11].E "sp|O00746|NDKM_HUMAN,tr|Q4TT34|Q4TT34_HUMAN,tr|A0A087WVT9|A0A087WVT9_HUMAN,tr|F2Z2X0|F2Z2X0_HUMAN" 4 1491.7305 1.79 95993 7610 2 1491.731111 746.8725 "Nucleoside diphosphate kinase, mitochondrial OS=Homo sapiens OX=9606 GN=NME4 PE=1 SV=1" 5.32 1755 - 153477 - - - 0.3834 - 2.21 0.33 - 241 1 2 0 0.0006 14 0 0 0 5.15E+06 2.89E+06 - - - 3.4682 1 221125_WJC_METTL3_EV_vs_WT_F07.07617.07617.2 2.13E-07 14/22 R.VSSDNVADLHEK.Y sp|P28074|PSB5_HUMAN 1 1312.6259 0.83 95998 7617 2 1312.62904 657.3202 Proteasome subunit beta type-5 OS=Homo sapiens OX=9606 GN=PSMB5 PE=1 SV=3 4.54 1756 - 241781 - - - 2.3853 - 2.876 0.607 - 829.5 1 2 0 0.0031 12 0 0 0 5.57E+06 6.75E+06 - - - 6.3029 0.9997 221125_WJC_METTL3_EV_vs_WT_F07.07618.07618.2 6.17E-06 18-Aug R.K[136.11]GPEADSEWR[166.11].R sp|Q14152|EIF3A_HUMAN 1 1191.5639 0.82 95999 7618 2 1191.562246 596.7892 Eukaryotic translation initiation factor 3 subunit A OS=Homo sapiens OX=9606 GN=EIF3A PE=1 SV=1 4.68 1756.2 - 179899 - - - -1.4057 - 1.967 0.436 - 238.7 1 2 0 -0.0017 10 0 0 0 6.00E+06 7.34E+06 - - - 4.1491 0.9999 221125_WJC_METTL3_EV_vs_WT_F07.07624.07624.3 5.88E-07 14/48 R.VC[160.03]DATYDKAPVEK.E "sp|Q12974|TP4A2_HUMAN,tr|E9PRR9|E9PRR9_HUMAN,tr|E9PMY3|E9PMY3_HUMAN,tr|E9PJC0|E9PJC0_HUMAN,tr|E9PML8|E9PML8_HUMAN" 5 1494.7024 0.97 96003 7624 3 1494.703299 499.2414 Protein tyrosine phosphatase type IVA 2 OS=Homo sapiens OX=9606 GN=PTP4A2 PE=1 SV=1 4.56 1756.9 - 976791 - - - 0.5714 - 2.56 0.551 - 364.2 1 2 1 0.0009 13 0 0 0 8.80E+06 9.08E+06 - - - 7.2315 0.9999 221125_WJC_METTL3_EV_vs_WT_F07.07625.07625.3 3.01E-06 Dec-36 R.K[136.11]GPEADSEWR[166.11].R sp|Q14152|EIF3A_HUMAN 1 1191.5639 0.9 96004 7625 3 1191.566824 398.1953 Eukaryotic translation initiation factor 3 subunit A OS=Homo sapiens OX=9606 GN=EIF3A PE=1 SV=1 4.68 1757 - 894808 - - - 2.4363 - 2.31 0.484 - 206.4 1 2 0 0.0029 10 0 0 0 2.08E+07 2.30E+07 - - - 6.3804 0.9006 221125_WJC_METTL3_EV_vs_WT_F07.07628.07628.2 3.13 14-May R.RPTWAEER.R "sp|Q8ND56|LS14A_HUMAN,tr|A0A096LP11|A0A096LP11_HUMAN,tr|A0A140TA76|A0A140TA76_HUMAN,tr|A0A0G2JQ95|A0A0G2JQ95_HUMAN" 4 1043.5148 1.04 96007 7628 2 1043.517404 522.7647 Protein LSM14 homolog A OS=Homo sapiens OX=9606 GN=LSM14A PE=1 SV=3 6.14 1757.4 - 198826 - - - 2.4552 - 1.239 0.046 - 82.1 3 2 0 0.0026 8 0 0 0 4.22E+07 4.05E+07 - - - -0.1868 0.9998 221125_WJC_METTL3_EV_vs_WT_F07.07632.07632.3 1.45E-05 13/44 R.VSSDNVADLHEK.Y sp|P28074|PSB5_HUMAN 1 1312.6259 0.7 96009 7632 3 1312.629315 438.5492 Proteasome subunit beta type-5 OS=Homo sapiens OX=9606 GN=PSMB5 PE=1 SV=3 4.54 1758 - 5.58E+06 - - - 2.5948 - 2.6 0.419 - 302.7 1 2 0 0.0034 12 0 0 0 5.78E+07 8.24E+07 - - - 5.859 0.9996 221125_WJC_METTL3_EV_vs_WT_F07.07634.07634.2 0.000415 18-Nov K.QDTVELQNQK[136.11].S sp|Q5VT06|CE350_HUMAN 1 1209.6081 2.32 96011 7634 2 1209.610504 605.8113 Centrosome-associated protein 350 OS=Homo sapiens OX=9606 GN=CEP350 PE=1 SV=1 4.37 1758.2 - 405114 - - - 2.0031 - 1.666 0.504 - 512.5 1 2 0 0.0024 10 0 0 0 2.84E+07 1.22E+07 - - - 4.1875 0.9994 221125_WJC_METTL3_EV_vs_WT_F07.07638.07638.3 1.42E-05 Sep-44 R.VSSDNVADLHEK[136.11].Y sp|P28074|PSB5_HUMAN 1 1320.6401 0.71 96014 7638 3 1320.64621 441.2206 Proteasome subunit beta type-5 OS=Homo sapiens OX=9606 GN=PSMB5 PE=1 SV=3 4.54 1758.7 - 7.47E+06 - - - 4.6197 - 2.067 0.484 - 171.7 1 2 0 0.0061 12 0 0 0 5.82E+07 8.24E+07 - - - 5.9471 0.9994 221125_WJC_METTL3_EV_vs_WT_F07.07640.07640.3 6.09E-07 14/48 K.IFSGSSHQDLSQK[136.11].L "sp|P60891|PRPS1_HUMAN,sp|P21108|PRPS3_HUMAN,tr|A0A2R8Y7H4|A0A2R8Y7H4_HUMAN,tr|Q15244|Q15244_HUMAN,tr|A0A6Q8PHK9|A0A6Q8PHK9_HUMAN,tr|B1ALA9|B1ALA9_HUMAN,tr|A0A6Q8PGF9|A0A6Q8PGF9_HUMAN,tr|B1ALA7|B1ALA7_HUMAN,tr|A0A0B4J207|A0A0B4J207_HUMAN" 9 1440.7089 0.55 96015 7640 3 1440.71428 481.2436 Ribose-phosphate pyrophosphokinase 1 OS=Homo sapiens OX=9606 GN=PRPS1 PE=1 SV=2 6.74 1758.9 - 1.23E+06 - - - 3.7641 - 2.334 0.404 - 199.2 1 2 0 0.0054 13 0 0 0 3.13E+07 5.68E+07 - - - 5.3407 0.9995 221125_WJC_METTL3_EV_vs_WT_F07.07641.07641.2 0.00094 20-Nov R.ESAINVAEGKK.Q "sp|Q9UJZ1|STML2_HUMAN,tr|A0A087WYB4|A0A087WYB4_HUMAN,tr|F2Z2I8|F2Z2I8_HUMAN" 3 1144.6088 1.46 96016 7641 2 1144.612162 573.3117 "Stomatin-like protein 2, mitochondrial OS=Homo sapiens OX=9606 GN=STOML2 PE=1 SV=1" 6.24 1759 - 791182 - - - 2.9355 - 2.463 0.474 - 483.5 1 2 0 0.0034 11 0 0 0 2.04E+07 1.40E+07 - - - 4.9794 0.9999 221125_WJC_METTL3_EV_vs_WT_F07.07642.07642.3 4.07E-07 16/48 K.IFSGSSHQDLSQK.L "sp|P60891|PRPS1_HUMAN,sp|P21108|PRPS3_HUMAN,tr|A0A2R8Y7H4|A0A2R8Y7H4_HUMAN,tr|Q15244|Q15244_HUMAN,tr|A0A6Q8PHK9|A0A6Q8PHK9_HUMAN,tr|B1ALA9|B1ALA9_HUMAN,tr|A0A6Q8PGF9|A0A6Q8PGF9_HUMAN,tr|B1ALA7|B1ALA7_HUMAN,tr|A0A0B4J207|A0A0B4J207_HUMAN" 9 1432.6947 0.55 96017 7642 3 1432.69865 478.5722 Ribose-phosphate pyrophosphokinase 1 OS=Homo sapiens OX=9606 GN=PRPS1 PE=1 SV=2 6.74 1759.1 - 784625 - - - 2.7871 - 2.995 0.463 - 272 1 2 0 0.004 13 0 0 0 3.13E+07 5.68E+07 - - - 6.675 0.9982 221125_WJC_METTL3_EV_vs_WT_F07.07644.07644.2 0.00274 20-Nov K.DKLDETGNSLK.V sp|P11388|TOP2A_HUMAN 1 1218.6092 0.62 96019 7644 2 1218.60895 610.3119 DNA topoisomerase 2-alpha OS=Homo sapiens OX=9606 GN=TOP2A PE=1 SV=3 4.56 1759.4 - 497651 - - - -0.2019 - 2.312 0.416 - 310.8 1 2 1 -0.0002 11 0 0 0 4.25E+06 6.87E+06 - - - 4.3808 0.9956 221125_WJC_METTL3_EV_vs_WT_F07.07645.07645.2 1.03E-05 18-Oct K.NRQEYDALAK.V "sp|Q6I9Y2|THOC7_HUMAN,tr|A0A5S6STF9|A0A5S6STF9_HUMAN" 2 1206.5993 0.64 96020 7645 2 1206.601325 604.3069 THO complex subunit 7 homolog OS=Homo sapiens OX=9606 GN=THOC7 PE=1 SV=3 6.07 1759.5 - 420706 - - - 1.6783 - 2.221 0.375 - 412.3 1 2 1 0.002 10 0 0 0 4.92E+06 7.68E+06 - - - 4.0375 0.9995 221125_WJC_METTL3_EV_vs_WT_F07.07647.07647.2 0.000773 24-Jul K.ETSMTEPSEPGSK.A sp|Q9UKJ3|GPTC8_HUMAN 1 1378.5922 0.35 96022 7647 2 1378.593878 690.3034 G patch domain-containing protein 8 OS=Homo sapiens OX=9606 GN=GPATCH8 PE=1 SV=2 4.25 1759.7 - 124137 - - - 1.1983 - 1.475 0.465 - 128.8 1 2 0 0.0017 13 0 0 0 1.86E+06 5.25E+06 - - - 3.4725 0.9993 221125_WJC_METTL3_EV_vs_WT_F07.07648.07648.2 0.00404 16-Jun K.KDWDDDQND.- "sp|P50990|TCPQ_HUMAN,tr|H7C2U0|H7C2U0_HUMAN" 2 1149.4211 0.31 96023 7648 2 1149.423422 575.7178 T-complex protein 1 subunit theta OS=Homo sapiens OX=9606 GN=CCT8 PE=1 SV=4 3.82 1759.9 - 73707.6 - - - 2.0541 - 1.158 0.57 - 136 1 2 0 0.0024 9 0 0 0 2.59E+06 8.39E+06 - - - 3.6747 0.9998 221125_WJC_METTL3_EV_vs_WT_F07.07651.07651.2 1.19E-05 22-Nov R.VSSDNVADLHEK[136.11].Y sp|P28074|PSB5_HUMAN 1 1320.6401 0.88 96025 7651 2 1320.642642 661.3273 Proteasome subunit beta type-5 OS=Homo sapiens OX=9606 GN=PSMB5 PE=1 SV=3 4.54 1760.2 - 345699 - - - 1.918 - 2.497 0.566 - 448.2 1 2 0 0.0025 12 0 0 0 5.98E+06 6.75E+06 - - - 5.6284 0.9942 221125_WJC_METTL3_EV_vs_WT_F07.07653.07653.2 0.00876 14-Oct R.R[166.11]PTWAEER[166.11].R "sp|Q8ND56|LS14A_HUMAN,tr|A0A096LP11|A0A096LP11_HUMAN,tr|A0A140TA76|A0A140TA76_HUMAN,tr|A0A0G2JQ95|A0A0G2JQ95_HUMAN" 4 1063.5314 1.13 96026 7653 2 1063.533723 532.773 Protein LSM14 homolog A OS=Homo sapiens OX=9606 GN=LSM14A PE=1 SV=3 6.14 1760.5 - 2.16E+06 - - - 2.2012 - 1.901 0.099 - 307.3 1 2 0 0.0023 8 0 0 0 4.63E+07 4.09E+07 - - - 1.7089 0.9999 221125_WJC_METTL3_EV_vs_WT_F07.07654.07654.3 9.95E-05 Oct-40 K.ETGFSHSQITR.L "sp|Q99653|CHP1_HUMAN,tr|F5GX29|F5GX29_HUMAN,tr|H0YKE7|H0YKE7_HUMAN,tr|H0YNG9|H0YNG9_HUMAN" 4 1261.6051 1.37 96027 7654 3 1261.60703 421.5423 Calcineurin B homologous protein 1 OS=Homo sapiens OX=9606 GN=CHP1 PE=1 SV=3 6.85 1760.6 - 894645 - - - 1.5187 - 2.103 0.469 - 183 1 2 0 0.0019 11 0 0 0 1.12E+07 8.17E+06 - - - 5.8801 0.9805 221125_WJC_METTL3_EV_vs_WT_F07.07656.07656.3 0.0205 Oct-40 K.GVLEQEEK[136.11]EEK[136.11].A sp|O14967|CLGN_HUMAN 1 1332.6744 7.49 96029 7656 3 1332.676915 445.2321 Calmegin OS=Homo sapiens OX=9606 GN=CLGN PE=1 SV=1 4.33 1760.9 - 379124 - - - 1.9052 - 1.639 0.249 - 89.3 1 2 1 0.0025 11 0 0 0 1.54E+08 2.05E+07 - - - 2.719 0.9998 221125_WJC_METTL3_EV_vs_WT_F07.07658.07658.2 9.71E-05 16-Aug K.K[136.11]DWDDDQND.- "sp|P50990|TCPQ_HUMAN,tr|H7C2U0|H7C2U0_HUMAN" 2 1157.4353 0.31 96031 7658 2 1157.437118 579.7249 T-complex protein 1 subunit theta OS=Homo sapiens OX=9606 GN=CCT8 PE=1 SV=4 3.82 1761.1 - 322817 - - - 1.6044 - 1.618 0.618 - 262.9 1 2 0 0.0019 9 0 0 0 2.10E+06 6.71E+06 - - - 4.9971 1 221125_WJC_METTL3_EV_vs_WT_F07.07659.07659.2 3.40E-06 14-Nov T.C[160.03]FHMDTC[160.03]K[136.11].Y "sp|Q86U44|MTA70_HUMAN,tr|H0YFV6|H0YFV6_HUMAN" 2 1105.4235 0.001 96032 7659 2 1105.421675 553.719 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 6.73 1761.2 - 291908 - - - -1.6121 - 1.947 0.655 - 545.2 1 1 0 -0.0018 8 0 0 0 0.00E+00 2.42E+06 - - - 5.8878 0.9998 221125_WJC_METTL3_EV_vs_WT_F07.07663.07663.2 1.19E-09 26-Dec R.GISSSNEGVEEPSK[136.11].K sp|Q9NXV6|CARF_HUMAN 1 1426.6667 0.27 96036 7663 2 1426.669101 714.3406 CDKN2A-interacting protein OS=Homo sapiens OX=9606 GN=CDKN2AIP PE=1 SV=3 4.25 1761.8 - 209933 - - - 1.6703 - 2.389 0.606 - 384.2 1 2 0 0.0024 14 0 0 0 4.86E+05 1.77E+06 - - - 5.7016 1 221125_WJC_METTL3_EV_vs_WT_F07.07667.07667.2 6.28E-07 13/20 K.TEELNKEVASN.S "sp|P08779|K1C16_HUMAN,sp|P19012|K1C15_HUMAN,tr|C9JTG5|C9JTG5_HUMAN,tr|A8MT21|A8MT21_HUMAN,tr|K7ENW6|K7ENW6_HUMAN" 5 1232.5885 12.17 96039 7667 2 1232.590227 617.3015 "Keratin, type I cytoskeletal 16 OS=Homo sapiens OX=9606 GN=KRT16 PE=1 SV=4" 4.25 1762.2 - 851511 - - - 1.4328 - 2.504 0.577 - 509.9 1 1 1 0.0018 11 0 0 0 8.32E+06 6.84E+05 - - - 5.7853 0.9999 221125_WJC_METTL3_EV_vs_WT_F07.07669.07669.3 0.000162 13/36 K.VQEFEHVNGR[166.11].W "sp|Q14839|CHD4_HUMAN,tr|A0A2R8Y4X2|A0A2R8Y4X2_HUMAN,tr|A0A2U3TZM0|A0A2U3TZM0_HUMAN,tr|A0A2R8Y5M9|A0A2R8Y5M9_HUMAN,tr|A0A2R8Y445|A0A2R8Y445_HUMAN,tr|A0A2R8YD40|A0A2R8YD40_HUMAN,tr|A0A2R8Y5J0|A0A2R8Y5J0_HUMAN,tr|A0A2R8Y425|A0A2R8Y425_HUMAN,tr|A0A2R8YFK9|A0A2R8YFK9_HUMAN,tr|A0A2R8Y8C1|A0A2R8Y8C1_HUMAN,tr|A0A0C4DGG9|A0A0C4DGG9_HUMAN,tr|A0A2R8YFD8|A0A2R8YFD8_HUMAN,tr|A0A2R8YDW2|A0A2R8YDW2_HUMAN,tr|A0A2R8Y7I0|A0A2R8Y7I0_HUMAN,tr|F5GWX5|F5GWX5_HUMAN,tr|A0A2R8YER1|A0A2R8YER1_HUMAN,tr|A0A2R8Y7M9|A0A2R8Y7M9_HUMAN,tr|A0A2R8Y521|A0A2R8Y521_HUMAN,tr|A0A2R8YDJ9|A0A2R8YDJ9_HUMAN,tr|A0A2R8Y212|A0A2R8Y212_HUMAN,tr|A0A2R8YE38|A0A2R8YE38_HUMAN" 21 1223.5923 0.98 96041 7669 3 1223.59441 408.8714 Chromodomain-helicase-DNA-binding protein 4 OS=Homo sapiens OX=9606 GN=CHD4 PE=1 SV=2 5.4 1762.4 - 2.13E+06 - - - 1.762 - 2.103 0.449 - 205.8 1 2 0 0.0022 10 0 0 0 1.85E+07 1.88E+07 - - - 5.7163 0.9762 221125_WJC_METTL3_EV_vs_WT_F07.07670.07670.3 0.00463 Oct-36 K.GWENHVEGQK.L "sp|Q14204|DYHC1_HUMAN,tr|A0A7P0T8N2|A0A7P0T8N2_HUMAN,tr|A0A7P0T9C4|A0A7P0T9C4_HUMAN,tr|A0A7P0TBJ7|A0A7P0TBJ7_HUMAN,tr|A0A804HHY6|A0A804HHY6_HUMAN,tr|A0A7P0T9K2|A0A7P0T9K2_HUMAN,tr|A0A7P0TB64|A0A7P0TB64_HUMAN,tr|A0A2R8Y706|A0A2R8Y706_HUMAN,tr|A0A7P0T916|A0A7P0T916_HUMAN,tr|A0A7P0TB75|A0A7P0TB75_HUMAN,tr|A0A7P0T8W5|A0A7P0T8W5_HUMAN,tr|A0A7P0T9S3|A0A7P0T9S3_HUMAN,tr|A0A7P0TAF3|A0A7P0TAF3_HUMAN,tr|A0A7P0T9F1|A0A7P0T9F1_HUMAN,tr|A0A7P0TAW9|A0A7P0TAW9_HUMAN,tr|A0A2R8YGC7|A0A2R8YGC7_HUMAN,tr|A0A7P0TA13|A0A7P0TA13_HUMAN,tr|A0A7P0T934|A0A7P0T934_HUMAN,tr|A0A7P0TAV5|A0A7P0TAV5_HUMAN,tr|A0A7P0T9Y3|A0A7P0T9Y3_HUMAN,tr|A0A7P0T7V5|A0A7P0T7V5_HUMAN,tr|A0A7P0T9R4|A0A7P0T9R4_HUMAN,tr|A0A2R8Y5T0|A0A2R8Y5T0_HUMAN,tr|A0A7P0T990|A0A7P0T990_HUMAN,tr|A0A7P0T942|A0A7P0T942_HUMAN,tr|A0A2R8YFZ7|A0A2R8YFZ7_HUMAN,tr|A0A7P0T825|A0A7P0T825_HUMAN,tr|A0A2R8Y6H2|A0A2R8Y6H2_HUMAN,tr|A0A7P0TBC9|A0A7P0TBC9_HUMAN,tr|A0A7P0TAM4|A0A7P0TAM4_HUMAN" 30 1182.5418 0.69 96042 7670 3 1182.544576 395.1879 Cytoplasmic dynein 1 heavy chain 1 OS=Homo sapiens OX=9606 GN=DYNC1H1 PE=1 SV=5 5.4 1762.5 - 832840 - - - 2.3602 - 1.726 0.151 - 163.2 1 2 0 0.0028 10 0 0 0 1.47E+07 2.14E+07 - - - 1.8167 0.9997 221125_WJC_METTL3_EV_vs_WT_F07.07672.07672.3 2.74E-06 Dec-40 R.DPNDVR[166.11]PIQAR[166.11].L "sp|Q9H307|PININ_HUMAN,tr|G3V5F0|G3V5F0_HUMAN,tr|G3V579|G3V579_HUMAN" 3 1299.6798 1.85 96044 7672 3 1299.682383 434.2339 Pinin OS=Homo sapiens OX=9606 GN=PNN PE=1 SV=5 5.96 1762.6 - 794003 - - - 1.9589 - 2.346 0.34 - 233.3 1 2 0 0.0025 11 0 0 0 2.36E+08 1.28E+08 - - - 4.7524 0.9995 221125_WJC_METTL3_EV_vs_WT_F07.07673.07673.3 0.00194 13/40 R.DPNDVRPIQAR.L "sp|Q9H307|PININ_HUMAN,tr|G3V5F0|G3V5F0_HUMAN,tr|G3V579|G3V579_HUMAN" 3 1279.6633 1.85 96045 7673 3 1279.666338 427.5617 Pinin OS=Homo sapiens OX=9606 GN=PNN PE=1 SV=5 5.96 1762.7 - 713196 - - - 2.3764 - 2.024 0.365 - 242.5 1 2 0 0.003 11 0 0 0 2.36E+08 1.28E+08 - - - 4.6115 1 221125_WJC_METTL3_EV_vs_WT_F07.07675.07675.2 2.34E-08 24-Dec K.IFSGSSHQDLSQK[136.11].L "sp|P60891|PRPS1_HUMAN,sp|P21108|PRPS3_HUMAN,tr|A0A2R8Y7H4|A0A2R8Y7H4_HUMAN,tr|Q15244|Q15244_HUMAN,tr|A0A6Q8PHK9|A0A6Q8PHK9_HUMAN,tr|B1ALA9|B1ALA9_HUMAN,tr|A0A6Q8PGF9|A0A6Q8PGF9_HUMAN,tr|B1ALA7|B1ALA7_HUMAN,tr|A0A0B4J207|A0A0B4J207_HUMAN" 9 1440.7089 0.68 96047 7675 2 1440.711224 721.3617 Ribose-phosphate pyrophosphokinase 1 OS=Homo sapiens OX=9606 GN=PRPS1 PE=1 SV=2 6.74 1763 - 348202 - - - 1.6429 - 2.476 0.6 - 365.3 1 2 0 0.0024 13 0 0 0 2.57E+06 3.81E+06 - - - 5.7988 0.975 221125_WJC_METTL3_EV_vs_WT_F07.07677.07677.2 0.509 16-Jun R.R[166.11]SLQAQLQR[166.11].L "sp|Q9NTJ5|SAC1_HUMAN,tr|E9PGZ4|E9PGZ4_HUMAN,tr|A0A5F9ZHN7|A0A5F9ZHN7_HUMAN,tr|C9JV50|C9JV50_HUMAN" 4 1118.6423 2.73 96049 7677 2 1118.644147 560.3284 Phosphatidylinositol-3-phosphatase SAC1 OS=Homo sapiens OX=9606 GN=SACM1L PE=1 SV=2 12 1763.2 - 247191 - - - 1.6243 - 1.298 0.101 - 57.9 2 2 0 0.0018 9 0 0 0 3.37E+06 1.23E+06 - - - 0.4065 0.9948 221125_WJC_METTL3_EV_vs_WT_F07.07681.07681.2 0.000522 22-Dec L.FSGSSHQDLSQK[136.11].L "sp|P60891|PRPS1_HUMAN,sp|P21108|PRPS3_HUMAN,tr|A0A2R8Y7H4|A0A2R8Y7H4_HUMAN,tr|Q15244|Q15244_HUMAN,tr|A0A6Q8PHK9|A0A6Q8PHK9_HUMAN,tr|B1ALA9|B1ALA9_HUMAN,tr|A0A6Q8PGF9|A0A6Q8PGF9_HUMAN,tr|B1ALA7|B1ALA7_HUMAN,tr|A0A0B4J207|A0A0B4J207_HUMAN" 9 1327.6248 0.96 96053 7681 2 1327.624895 664.8197 Ribose-phosphate pyrophosphokinase 1 OS=Homo sapiens OX=9606 GN=PRPS1 PE=1 SV=2 6.74 1763.8 - 120902 - - - 0.0768 - 2.617 0.537 - 400.9 1 1 0 0.0001 12 0 0 0 9.42E+05 9.77E+05 - - - 5.5385 1 221125_WJC_METTL3_EV_vs_WT_F07.07682.07682.2 8.09E-11 Oct-34 R.LVSGGGAC[160.03]SDTGAC[160.03]TPAR.S sp|Q9UJC3|HOOK1_HUMAN 1 1735.7618 1.78 96054 7682 2 1735.764751 868.8882 Protein Hook homolog 1 OS=Homo sapiens OX=9606 GN=HOOK1 PE=1 SV=2 5.82 1763.9 - 104835 - - - 1.7186 - 2.552 0.636 - 277.3 1 2 0 0.003 18 0 0 0 1.96E+06 1.10E+06 - - - 6.0409 1 221125_WJC_METTL3_EV_vs_WT_F07.07683.07683.2 1.83E-10 13/34 R.LVSGGGAC[160.03]SDTGAC[160.03]TPAR[166.11].S sp|Q9UJC3|HOOK1_HUMAN 1 1745.77 1.78 96055 7683 2 1745.774666 873.8923 Protein Hook homolog 1 OS=Homo sapiens OX=9606 GN=HOOK1 PE=1 SV=2 5.82 1764 - 81794.8 - - - 2.651 - 2.842 0.744 - 495.5 1 2 0 0.0046 18 0 0 0 1.96E+06 1.10E+06 - - - 7.1027 0.9855 221125_WJC_METTL3_EV_vs_WT_F07.07684.07684.2 0.000548 26-Jul K.VANPSSDADGQSLK[136.11].V sp|Q8IWI9|MGAP_HUMAN 1 1395.6721 1.39 96056 7684 2 1395.681186 698.8433 MAX gene-associated protein OS=Homo sapiens OX=9606 GN=MGA PE=1 SV=4 4.21 1764.2 - 79038.4 - - - 6.4836 - 1.632 0.459 - 124 1 2 0 0.009 14 0 0 0 2.80E+06 2.02E+06 - - - 3.6575 0.8632 221125_WJC_METTL3_EV_vs_WT_F07.07686.07686.2 0.0324 20-Jun K.EFSNSNNLDNK[136.11].S "sp|O60315|ZEB2_HUMAN,tr|U3KQ51|U3KQ51_HUMAN,tr|A0JP08|A0JP08_HUMAN,tr|A0A6Q8PH34|A0A6Q8PH34_HUMAN,tr|A0A1B0GW50|A0A1B0GW50_HUMAN,tr|A0A1B0GV02|A0A1B0GV02_HUMAN,tr|A0A1B0GVV8|A0A1B0GVV8_HUMAN" 7 1288.5775 0.93 96057 7686 2 1289.582295 645.296 Zinc finger E-box-binding homeobox 2 OS=Homo sapiens OX=9606 GN=ZEB2 PE=1 SV=1 4.37 1764.4 - 167333 - - - 779.7637 - 1.046 0.365 - 86.7 1 2 0 1.0048 11 0 0 0 4.84E+06 5.22E+06 - - - 1.5431 0.9994 221125_WJC_METTL3_EV_vs_WT_F07.07689.07689.3 0.00134 Jul-36 K.YNHIDESEMK[136.11].K "sp|Q92598|HS105_HUMAN,tr|Q5TBM3|Q5TBM3_HUMAN,tr|A0A0A0MSM0|A0A0A0MSM0_HUMAN" 3 1272.5536 0.16 96059 7689 3 1272.556568 425.1918 Heat shock protein 105 kDa OS=Homo sapiens OX=9606 GN=HSPH1 PE=1 SV=1 4.65 1764.7 - 1.90E+06 - - - 2.3307 - 1.397 0.438 - 49.5 1 2 0 0.003 10 0 0 0 8.44E+06 5.30E+07 - - - 4.3988 0.9999 221125_WJC_METTL3_EV_vs_WT_F07.07690.07690.3 3.93E-05 16/48 R.LAQDGAHVVVSSR[166.11].K "sp|Q9BTZ2|DHRS4_HUMAN,tr|F5GWZ1|F5GWZ1_HUMAN" 2 1347.7134 1.49 96060 7690 3 1347.716339 450.2451 Dehydrogenase\reductase SDR family member 4 OS=Homo sapiens OX=9606 GN=DHRS4 PE=1 SV=3 6.74 1764.7 - 1.11E+06 - - - 2.157 - 2.863 0.468 - 536.6 1 2 0 0.0029 13 0 0 0 1.94E+08 1.31E+08 - - - 6.6089 0.9997 221125_WJC_METTL3_EV_vs_WT_F07.07694.07694.2 0.00993 18-Sep R.SISQSISGQK.- "sp|Q8WXI9|P66B_HUMAN,tr|A0A0U1RRM1|A0A0U1RRM1_HUMAN" 2 1033.5404 2.2 96063 7694 2 1033.540721 517.7775 Transcriptional repressor p66-beta OS=Homo sapiens OX=9606 GN=GATAD2B PE=1 SV=1 8.47 1765.1 - 506338 - - - 0.3222 - 1.744 0.404 - 189.5 1 2 0 0.0003 10 0 0 0 1.23E+07 5.58E+06 - - - 3.5773 0.9942 221125_WJC_METTL3_EV_vs_WT_F07.07698.07698.2 0.000345 18-Jul K.GWENHVEGQK.L "sp|Q14204|DYHC1_HUMAN,tr|A0A7P0T8N2|A0A7P0T8N2_HUMAN,tr|A0A7P0T9C4|A0A7P0T9C4_HUMAN,tr|A0A7P0TBJ7|A0A7P0TBJ7_HUMAN,tr|A0A804HHY6|A0A804HHY6_HUMAN,tr|A0A7P0T9K2|A0A7P0T9K2_HUMAN,tr|A0A7P0TB64|A0A7P0TB64_HUMAN,tr|A0A2R8Y706|A0A2R8Y706_HUMAN,tr|A0A7P0T916|A0A7P0T916_HUMAN,tr|A0A7P0TB75|A0A7P0TB75_HUMAN,tr|A0A7P0T8W5|A0A7P0T8W5_HUMAN,tr|A0A7P0T9S3|A0A7P0T9S3_HUMAN,tr|A0A7P0TAF3|A0A7P0TAF3_HUMAN,tr|A0A7P0T9F1|A0A7P0T9F1_HUMAN,tr|A0A7P0TAW9|A0A7P0TAW9_HUMAN,tr|A0A2R8YGC7|A0A2R8YGC7_HUMAN,tr|A0A7P0TA13|A0A7P0TA13_HUMAN,tr|A0A7P0T934|A0A7P0T934_HUMAN,tr|A0A7P0TAV5|A0A7P0TAV5_HUMAN,tr|A0A7P0T9Y3|A0A7P0T9Y3_HUMAN,tr|A0A7P0T7V5|A0A7P0T7V5_HUMAN,tr|A0A7P0T9R4|A0A7P0T9R4_HUMAN,tr|A0A2R8Y5T0|A0A2R8Y5T0_HUMAN,tr|A0A7P0T990|A0A7P0T990_HUMAN,tr|A0A7P0T942|A0A7P0T942_HUMAN,tr|A0A2R8YFZ7|A0A2R8YFZ7_HUMAN,tr|A0A7P0T825|A0A7P0T825_HUMAN,tr|A0A2R8Y6H2|A0A2R8Y6H2_HUMAN,tr|A0A7P0TBC9|A0A7P0TBC9_HUMAN,tr|A0A7P0TAM4|A0A7P0TAM4_HUMAN" 30 1182.5418 0.35 96067 7698 2 1182.545912 592.2782 Cytoplasmic dynein 1 heavy chain 1 OS=Homo sapiens OX=9606 GN=DYNC1H1 PE=1 SV=5 5.4 1765.6 - 258727 - - - 3.4899 - 1.702 0.265 - 184.2 1 2 0 0.0041 10 0 0 0 1.87E+06 5.40E+06 - - - 2.4814 0.9998 221125_WJC_METTL3_EV_vs_WT_F07.07699.07699.2 0.000406 16-Sep K.GHEFYNPQK.K sp|P78406|RAE1L_HUMAN 1 1118.5145 1.72 96068 7699 2 1118.515108 560.2645 mRNA export factor OS=Homo sapiens OX=9606 GN=RAE1 PE=1 SV=1 6.75 1765.8 - 217496 - - - 0.5364 - 1.961 0.481 - 328.7 1 2 0 0.0006 9 0 0 0 1.73E+07 1.01E+07 - - - 4.5418 1 221125_WJC_METTL3_EV_vs_WT_F07.07702.07702.2 3.72E-07 28-Nov L.QTTQSVEGATGSAVK.S "sp|Q14157|UBP2L_HUMAN,tr|F8W726|F8W726_HUMAN" 2 1462.7264 2.26 96071 7702 2 1462.729628 732.3705 Ubiquitin-associated protein 2-like OS=Homo sapiens OX=9606 GN=UBAP2L PE=1 SV=2 6 1766.1 - 155616 - - - 2.2403 - 2.671 0.621 - 431.9 1 1 0 0.0033 15 0 0 0 8.09E+06 3.57E+06 - - - 6.0421 0.9999 221125_WJC_METTL3_EV_vs_WT_F07.07703.07703.2 1.77E-09 17/24 R.LAQDGAHVVVSSR.K "sp|Q9BTZ2|DHRS4_HUMAN,tr|F5GWZ1|F5GWZ1_HUMAN" 2 1337.7052 1.54 96072 7703 2 1337.706636 669.8599 Dehydrogenase\reductase SDR family member 4 OS=Homo sapiens OX=9606 GN=DHRS4 PE=1 SV=3 6.74 1766.3 - 134714 - - - 1.1019 - 3.239 0.469 - 1371.3 1 2 0 0.0015 13 0 0 0 2.64E+07 1.71E+07 - - - 5.5209 0.9997 221125_WJC_METTL3_EV_vs_WT_F07.07706.07706.2 7.93E-06 22-Oct R.AQAALQAQQVNR[166.11].T "sp|P49848|TAF6_HUMAN,tr|J3KR72|J3KR72_HUMAN" 2 1306.6981 0.42 96075 7706 2 1306.700693 654.3563 Transcription initiation factor TFIID subunit 6 OS=Homo sapiens OX=9606 GN=TAF6 PE=1 SV=1 9.79 1766.7 - 84118 - - - 1.9714 - 2.052 0.555 - 371.8 1 2 0 0.0026 12 0 0 0 5.21E+05 1.23E+06 - - - 5.0307 0.9999 221125_WJC_METTL3_EV_vs_WT_F07.07709.07709.3 0.000777 13/32 R.SFQDNLHNR[166.11].K sp|Q9UDW3|ZMAT5_HUMAN 1 1139.5347 0.001 96076 7709 3 1139.535224 380.8522 Zinc finger matrin-type protein 5 OS=Homo sapiens OX=9606 GN=ZMAT5 PE=1 SV=1 6.46 1767.1 - 1.04E+06 - - - 0.4247 - 1.896 0.408 - 267.3 1 2 0 0.0005 9 0 0 0 0.00E+00 1.13E+07 - - - 5.0167 0.9015 221125_WJC_METTL3_EV_vs_WT_F07.07710.07710.2 2.43 20-Aug R.DPNDVR[166.11]PIQAR[166.11].L "sp|Q9H307|PININ_HUMAN,tr|G3V5F0|G3V5F0_HUMAN,tr|G3V579|G3V579_HUMAN" 3 1299.6798 2.24 96077 7710 2 1299.68392 650.8472 Pinin OS=Homo sapiens OX=9606 GN=PNN PE=1 SV=5 5.96 1767.2 - 871416 - - - 3.1415 - 1.113 0.108 - 70.9 1 2 0 0.0041 11 0 0 0 2.55E+07 1.14E+07 - - - 0.127 0.9895 221125_WJC_METTL3_EV_vs_WT_F07.07713.07713.3 0.016 Jul-36 K.YNHIDESEMK.K "sp|Q92598|HS105_HUMAN,tr|Q5TBM3|Q5TBM3_HUMAN,tr|A0A0A0MSM0|A0A0A0MSM0_HUMAN" 3 1264.5394 0.16 96080 7713 3 1264.542279 422.5204 Heat shock protein 105 kDa OS=Homo sapiens OX=9606 GN=HSPH1 PE=1 SV=1 4.65 1767.5 - 888993 - - - 2.2751 - 1.387 0.251 - 46.9 1 2 0 0.0029 10 0 0 0 8.35E+06 5.31E+07 - - - 2.293 1 221125_WJC_METTL3_EV_vs_WT_F07.07714.07714.2 9.31E-07 16/24 R.LAQDGAHVVVSSR[166.11].K "sp|Q9BTZ2|DHRS4_HUMAN,tr|F5GWZ1|F5GWZ1_HUMAN" 2 1347.7134 1.54 96081 7714 2 1347.715168 674.864 Dehydrogenase\reductase SDR family member 4 OS=Homo sapiens OX=9606 GN=DHRS4 PE=1 SV=3 6.74 1767.7 - 780099 - - - 1.2881 - 3.062 0.57 - 1187.4 1 2 0 0.0017 13 0 0 0 2.64E+07 1.71E+07 - - - 6.1226 1 221125_WJC_METTL3_EV_vs_WT_F07.07715.07715.3 0.000394 Dec-48 K.IIHEDGYSEDEC[160.03]K[136.11].Q sp|P08754|GNAI3_HUMAN 1 1601.6759 1.01 96082 7715 3 1601.676192 534.8992 Guanine nucleotide-binding protein G(i) subunit alpha-3 OS=Homo sapiens OX=9606 GN=GNAI3 PE=1 SV=3 4.17 1767.8 - 757895 - - - 0.1811 - 1.653 0.561 - 128.6 1 2 0 0.0003 13 0 0 0 5.80E+06 5.73E+06 - - - 6.1572 0.9947 221125_WJC_METTL3_EV_vs_WT_F07.07716.07716.3 0.0993 Sep-40 R.SPPLHEHPLYK.D "sp|Q9BZE1|RM37_HUMAN,tr|S4R369|S4R369_HUMAN" 2 1316.6877 1.11 96083 7716 3 1316.691 439.9032 "39S ribosomal protein L37, mitochondrial OS=Homo sapiens OX=9606 GN=MRPL37 PE=1 SV=2" 6.66 1767.9 - 381537 - - - 2.4903 - 1.631 0.261 - 106.2 1 2 0 0.0033 11 0 0 0 8.59E+06 7.77E+06 - - - 2.8387 0.9901 221125_WJC_METTL3_EV_vs_WT_F07.07718.07718.3 0.111 Nov-36 K.TYIPPK[136.11]GETK[136.11].K "sp|B2RPK0|HGB1A_HUMAN,sp|P09429|HMGB1_HUMAN,tr|Q5T7C4|Q5T7C4_HUMAN" 3 1148.6412 0.001 96085 7718 3 1148.642699 383.8877 Putative high mobility group protein B1-like 1 OS=Homo sapiens OX=9606 GN=HMGB1P1 PE=5 SV=1 8.17 1768.2 - 336024 - - - 1.2833 - 1.717 0.253 - 171.6 1 2 1 0.0015 10 0 0 0 0.00E+00 5.35E+06 - - - 2.939 1 221125_WJC_METTL3_EV_vs_WT_F07.07719.07719.2 6.28E-08 28-Dec L.QTTQSVEGATGSAVK[136.11].S "sp|Q14157|UBP2L_HUMAN,tr|F8W726|F8W726_HUMAN" 2 1470.7406 2.26 96086 7719 2 1470.741375 736.3776 Ubiquitin-associated protein 2-like OS=Homo sapiens OX=9606 GN=UBAP2L PE=1 SV=2 6 1768.3 - 323678 - - - 0.5603 - 2.682 0.627 - 509.7 1 1 0 0.0008 15 0 0 0 8.09E+06 3.57E+06 - - - 6.0973 0.9999 221125_WJC_METTL3_EV_vs_WT_F07.07720.07720.2 3.68E-06 16-Sep R.SFQDNLHNR.K sp|Q9UDW3|ZMAT5_HUMAN 1 1129.5265 1.89 96087 7720 2 1129.526389 565.7705 Zinc finger matrin-type protein 5 OS=Homo sapiens OX=9606 GN=ZMAT5 PE=1 SV=1 6.46 1768.4 - 283783 - - - -0.0717 - 1.833 0.503 - 298.8 1 2 0 -0.0001 9 0 0 0 4.28E+06 2.26E+06 - - - 4.5092 0.9294 221125_WJC_METTL3_EV_vs_WT_F07.07721.07721.2 0.673 20-May K.EFSNSNNLDNK[136.11].S "sp|O60315|ZEB2_HUMAN,tr|U3KQ51|U3KQ51_HUMAN,tr|A0JP08|A0JP08_HUMAN,tr|A0A6Q8PH34|A0A6Q8PH34_HUMAN,tr|A0A1B0GW50|A0A1B0GW50_HUMAN,tr|A0A1B0GV02|A0A1B0GV02_HUMAN,tr|A0A1B0GVV8|A0A1B0GVV8_HUMAN" 7 1288.5775 0.93 96088 7721 2 1288.58039 645.296 Zinc finger E-box-binding homeobox 2 OS=Homo sapiens OX=9606 GN=ZEB2 PE=1 SV=1 4.37 1768.5 - 182296 - - - 2.2358 - 0.978 0.132 - 74 1 2 0 0.0029 11 0 0 0 4.84E+06 5.22E+06 - - - -0.0451 0.9998 221125_WJC_METTL3_EV_vs_WT_F07.07728.07728.2 2.93E-05 18-Oct K.YNHIDESEMK[136.11].K "sp|Q92598|HS105_HUMAN,tr|Q5TBM3|Q5TBM3_HUMAN,tr|A0A0A0MSM0|A0A0A0MSM0_HUMAN" 3 1272.5536 0.06 96093 7728 2 1272.555549 637.2841 Heat shock protein 105 kDa OS=Homo sapiens OX=9606 GN=HSPH1 PE=1 SV=1 4.65 1769.3 - 1.15E+06 - - - 1.53 - 1.907 0.551 - 485.9 1 2 0 0.0019 10 0 0 0 9.37E+05 1.55E+07 - - - 4.9119 0.9948 221125_WJC_METTL3_EV_vs_WT_F07.07729.07729.2 1.49E-05 16/26 L.ALTQSVGGDSSADR[166.11].L "sp|Q86U44|MTA70_HUMAN,tr|H0YFV6|H0YFV6_HUMAN" 2 1372.6458 0.001 96094 7729 2 1372.645871 687.3302 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 4.21 1769.4 - 1.02E+06 - - - 0.0474 - 2.914 0.517 - 866 1 1 0 0.0001 14 0 0 0 0.00E+00 1.26E+07 - - - 5.5435 0.9921 221125_WJC_METTL3_EV_vs_WT_F07.07733.07733.2 1.68E-06 20-Sep A.QDGAHVVVSSR[166.11].K "sp|Q9BTZ2|DHRS4_HUMAN,tr|F5GWZ1|F5GWZ1_HUMAN" 2 1163.5923 2.14 96098 7733 2 1163.592512 582.8034 Dehydrogenase\reductase SDR family member 4 OS=Homo sapiens OX=9606 GN=DHRS4 PE=1 SV=3 6.74 1769.9 - 366578 - - - 0.2217 - 2.017 0.514 - 219.5 1 1 0 0.0003 11 0 0 0 4.68E+06 2.19E+06 - - - 4.7353 0.9972 221125_WJC_METTL3_EV_vs_WT_F07.07734.07734.2 0.0139 16-Jul K.ITITNDQNR[166.11].L "sp|P11021|BIP_HUMAN,tr|A0A7P0TB36|A0A7P0TB36_HUMAN,tr|A0A7P0TAI0|A0A7P0TAI0_HUMAN" 3 1083.5548 0.52 96099 7734 2 1083.557014 542.7847 Endoplasmic reticulum chaperone BiP OS=Homo sapiens OX=9606 GN=HSPA5 PE=1 SV=2 5.84 1770 - 315024 - - - 2.0377 - 1.516 0.268 - 120.9 1 2 0 0.0022 9 0 0 0 1.11E+06 2.15E+06 - - - 2.2235 0.9921 221125_WJC_METTL3_EV_vs_WT_F07.07735.07735.2 0.000572 20-Aug R.TKQPIPAAYNR.Y "sp|Q6P1J9|CDC73_HUMAN,tr|A0A2R8YHB3|A0A2R8YHB3_HUMAN,tr|A0A3B3IRP5|A0A3B3IRP5_HUMAN" 3 1257.683 1.42 96100 7735 2 1257.682716 629.8488 Parafibromin OS=Homo sapiens OX=9606 GN=CDC73 PE=1 SV=1 9.99 1770.1 - 308962 - - - -0.202 - 1.902 0.256 - 227.1 1 2 1 -0.0003 11 0 0 0 5.52E+06 3.89E+06 - - - 2.6709 0.9997 221125_WJC_METTL3_EV_vs_WT_F07.07736.07736.2 9.75E-05 16-Sep R.SFQDNLHNR[166.11].K sp|Q9UDW3|ZMAT5_HUMAN 1 1139.5347 1.93 96101 7736 2 1139.533708 570.7746 Zinc finger matrin-type protein 5 OS=Homo sapiens OX=9606 GN=ZMAT5 PE=1 SV=1 6.46 1770.3 - 305219 - - - -0.9056 - 1.484 0.512 - 292.1 1 2 0 -0.001 9 0 0 0 4.28E+06 2.21E+06 - - - 3.9643 0.994 221125_WJC_METTL3_EV_vs_WT_F07.07740.07740.3 0.00653 Dec-36 K.LNSIK[136.11]DVEQK[136.11].K sp|P61221|ABCE1_HUMAN 1 1188.6685 0.91 96103 7740 3 1188.669092 397.2301 ATP-binding cassette sub-family E member 1 OS=Homo sapiens OX=9606 GN=ABCE1 PE=1 SV=1 6.07 1770.8 - 960787 - - - 0.4964 - 1.612 0.286 - 130.1 1 2 1 0.0006 10 0 0 0 8.38E+06 9.25E+06 - - - 3.1229 0.9995 221125_WJC_METTL3_EV_vs_WT_F07.07746.07746.3 0.0239 Aug-36 R.ADVQHLEDDR.H "sp|Q53EZ4|CEP55_HUMAN,tr|H0Y432|H0Y432_HUMAN" 2 1196.5422 1.76 96109 7746 3 1196.541846 399.8547 Centrosomal protein of 55 kDa OS=Homo sapiens OX=9606 GN=CEP55 PE=1 SV=3 4.22 1771.5 - 373920 - - - -0.2783 - 1.731 0.335 - 105.7 1 2 0 -0.0003 10 0 0 0 2.66E+06 1.51E+06 - - - 3.8773 1 221125_WJC_METTL3_EV_vs_WT_F07.07754.07754.3 1.33E-05 13/52 K.LHDSSGSQVGTGFK.S sp|P49792|RBP2_HUMAN 1 1418.679 1 96115 7754 3 1418.681287 473.9003 E3 SUMO-protein ligase RanBP2 OS=Homo sapiens OX=9606 GN=RANBP2 PE=1 SV=2 6.74 1772.4 - 991488 - - - 1.6071 - 2.57 0.518 - 277.4 1 2 0 0.0023 14 0 0 0 2.27E+07 2.26E+07 - - - 6.823 0.998 221125_WJC_METTL3_EV_vs_WT_F07.07755.07755.3 0.0232 Oct-36 K.LNSIKDVEQK.K sp|P61221|ABCE1_HUMAN 1 1172.6401 0.91 96116 7755 3 1172.639435 391.8873 ATP-binding cassette sub-family E member 1 OS=Homo sapiens OX=9606 GN=ABCE1 PE=1 SV=1 6.07 1772.5 - 804875 - - - -0.5688 - 1.94 0.309 - 85.1 1 2 1 -0.0007 10 0 0 0 8.38E+06 9.25E+06 - - - 3.9202 0.9999 221125_WJC_METTL3_EV_vs_WT_F07.07756.07756.2 2.10E-05 16-Sep K.GHEFYNPQK[136.11].K sp|P78406|RAE1L_HUMAN 1 1126.5287 1.78 96117 7756 2 1126.528309 564.2716 mRNA export factor OS=Homo sapiens OX=9606 GN=RAE1 PE=1 SV=1 6.75 1772.6 - 551319 - - - -0.3542 - 2.275 0.569 - 316 1 2 0 -0.0004 9 0 0 0 1.62E+07 9.11E+06 - - - 5.6215 0.9982 221125_WJC_METTL3_EV_vs_WT_F07.07758.07758.3 0.00884 Sep-40 R.SPPLHEHPLYK[136.11].D "sp|Q9BZE1|RM37_HUMAN,tr|S4R369|S4R369_HUMAN" 2 1324.7019 1.17 96119 7758 3 1324.703802 442.5746 "39S ribosomal protein L37, mitochondrial OS=Homo sapiens OX=9606 GN=MRPL37 PE=1 SV=2" 6.66 1772.8 - 363407 - - - 1.4199 - 1.633 0.287 - 79.4 1 2 0 0.0019 11 0 0 0 9.25E+06 7.91E+06 - - - 3.1324 0.8451 221125_WJC_METTL3_EV_vs_WT_F07.07760.07760.3 0.824 Jul-44 K.ILITTSDRPHGR.T sp|Q9H9Y2|RPF1_HUMAN 1 1364.7524 1.3 96121 7760 3 1364.751982 455.9248 Ribosome production factor 1 OS=Homo sapiens OX=9606 GN=RPF1 PE=1 SV=2 9.61 1773.1 - 286463 - - - -0.3407 - 1.783 0.028 - 73.1 4 2 0 -0.0005 12 0 0 0 3.11E+06 2.39E+06 - - - 0.1764 0.9989 221125_WJC_METTL3_EV_vs_WT_F07.07766.07766.3 0.000123 Sep-48 K.LEDYDK[136.11]AETEASK[136.11].A "sp|Q9H3U1|UN45A_HUMAN,tr|A0A1W2PNX8|A0A1W2PNX8_HUMAN" 2 1513.7119 0.5 96125 7766 3 1513.711864 505.5779 Protein unc-45 homolog A OS=Homo sapiens OX=9606 GN=UNC45A PE=1 SV=1 4.18 1773.9 - 283324 - - - -0.0126 - 1.885 0.374 - 88.7 1 2 1 0 13 0 0 0 4.00E+06 8.07E+06 - - - 4.4285 0.9998 221125_WJC_METTL3_EV_vs_WT_F07.07768.07768.2 0.0833 20-Sep R.C[160.03]EVC[160.03]NYSTTTK.G "sp|Q86UP3|ZFHX4_HUMAN,sp|Q15911|ZFHX3_HUMAN,tr|E5RI93|E5RI93_HUMAN,tr|E7EVZ1|E7EVZ1_HUMAN" 4 1361.5592 1.41 96127 7768 2 1361.557885 681.7869 Zinc finger homeobox protein 4 OS=Homo sapiens OX=9606 GN=ZFHX4 PE=1 SV=1 5.99 1774.2 - 201506 - - - -0.9306 - 1.902 0.47 - 249 1 2 0 -0.0013 11 0 0 0 2.74E+06 1.94E+06 - - - 4.2512 0.9999 221125_WJC_METTL3_EV_vs_WT_F07.07769.07769.2 4.78E-05 26-Nov K.SAQQEASADVATPK.M sp|Q8WYP5|ELYS_HUMAN 1 1401.6736 1.11 96128 7769 2 1401.673175 701.8441 Protein ELYS OS=Homo sapiens OX=9606 GN=AHCTF1 PE=1 SV=3 4.37 1774.3 - 198438 - - - -0.2939 - 2.419 0.478 - 128.9 1 2 0 -0.0004 14 0 0 0 2.15E+06 1.94E+06 - - - 4.7881 0.9999 221125_WJC_METTL3_EV_vs_WT_F07.07770.07770.2 4.68E-06 26-Oct K.SAQQEASADVATPK[136.11].M sp|Q8WYP5|ELYS_HUMAN 1 1409.6878 1.11 96129 7770 2 1409.686586 705.8512 Protein ELYS OS=Homo sapiens OX=9606 GN=AHCTF1 PE=1 SV=3 4.37 1774.4 - 132096 - - - -0.852 - 2.282 0.533 - 311.1 1 2 0 -0.0012 14 0 0 0 2.15E+06 1.94E+06 - - - 5.0478 0.9984 221125_WJC_METTL3_EV_vs_WT_F07.07774.07774.3 0.03 13/40 K.EETQPPVALKK.E sp|Q8NC51|PAIRB_HUMAN 1 1238.6871 0.8 96131 7774 3 1238.689502 413.903 Plasminogen activator inhibitor 1 RNA-binding protein OS=Homo sapiens OX=9606 GN=SERBP1 PE=1 SV=2 6.24 1775 - 1.63E+06 - - - 1.9771 - 2.154 0.245 - 242.3 1 2 0 0.0024 11 0 0 0 1.59E+09 2.00E+09 - - - 3.4507 0.8066 221125_WJC_METTL3_EV_vs_WT_F07.07775.07775.3 0.00345 Nov-44 K.SR[166.11]AEAALEEESR[166.11].Q "sp|Q969G3|SMCE1_HUMAN,tr|A0A2R8Y855|A0A2R8Y855_HUMAN,tr|A0A2R8YES3|A0A2R8YES3_HUMAN,tr|A0A2U3TZQ7|A0A2U3TZQ7_HUMAN,tr|A0A2R8Y7U4|A0A2R8Y7U4_HUMAN,tr|B4DGM3|B4DGM3_HUMAN,tr|A0A2R8YD78|A0A2R8YD78_HUMAN,tr|J3QKS7|J3QKS7_HUMAN,tr|A0A2R8Y4T4|A0A2R8Y4T4_HUMAN,tr|A0A2R8Y7I9|A0A2R8Y7I9_HUMAN,tr|J3QR61|J3QR61_HUMAN,tr|A0A2R8Y765|A0A2R8Y765_HUMAN,tr|J3KT85|J3KT85_HUMAN" 13 1366.6592 2.09 96132 7775 3 1366.668463 456.5603 SWI\SNF-related matrix-associated actin-dependent regulator of chromatin subfamily E member 1 OS=Homo sapiens OX=9606 GN=SMARCE1 PE=1 SV=2 4.49 1775.1 - 638971 - - - 6.8056 - 2.423 0.209 - 280.5 1 2 1 0.0093 12 0 0 0 3.33E+07 1.59E+07 - - - 3.3207 0.999 221125_WJC_METTL3_EV_vs_WT_F07.07776.07776.3 0.00847 13/56 R.HVAAGTQQPYTDGVR.M sp|P14923|PLAK_HUMAN 1 1598.7801 7.11 96133 7776 3 1598.782242 533.934 Junction plakoglobin OS=Homo sapiens OX=9606 GN=JUP PE=1 SV=3 6.74 1775.2 - 329504 - - - 1.3285 - 1.74 0.315 - 212.7 1 2 0 0.0021 15 0 0 0 3.31E+06 4.65E+05 - - - 3.4966 0.92 221125_WJC_METTL3_EV_vs_WT_F07.07778.07778.2 0.00308 18-Jul K.EGVK[136.11]FDESEK[136.11].T "sp|P14625|ENPL_HUMAN,tr|A0A7P0T917|A0A7P0T917_HUMAN,tr|A0A7P0T823|A0A7P0T823_HUMAN,tr|A0A7P0TAE1|A0A7P0TAE1_HUMAN,tr|H0YIV0|H0YIV0_HUMAN,tr|A0A7P0TAY2|A0A7P0TAY2_HUMAN,tr|A0A087WT78|A0A087WT78_HUMAN,tr|A0A7P0TAT8|A0A7P0TAT8_HUMAN" 8 1182.5739 1.4 96135 7778 2 1182.578487 592.2942 Endoplasmin OS=Homo sapiens OX=9606 GN=HSP90B1 PE=1 SV=1 4.41 1775.4 - 90352.8 - - - 3.8509 - 1.265 0.374 - 129.7 1 2 1 0.0046 10 0 0 0 5.49E+06 3.92E+06 - - - 2.4581 0.9805 221125_WJC_METTL3_EV_vs_WT_F07.07779.07779.2 0.0199 18-Jun K.EGVKFDESEK.T "sp|P14625|ENPL_HUMAN,tr|A0A7P0T917|A0A7P0T917_HUMAN,tr|A0A7P0T823|A0A7P0T823_HUMAN,tr|A0A7P0TAE1|A0A7P0TAE1_HUMAN,tr|H0YIV0|H0YIV0_HUMAN,tr|A0A7P0TAY2|A0A7P0TAY2_HUMAN,tr|A0A087WT78|A0A087WT78_HUMAN,tr|A0A7P0TAT8|A0A7P0TAT8_HUMAN" 8 1166.5455 3.39 96136 7779 2 1166.546222 584.28 Endoplasmin OS=Homo sapiens OX=9606 GN=HSP90B1 PE=1 SV=1 4.41 1775.6 - 86299.1 - - - 0.5906 - 1.155 0.344 - 87.9 1 2 1 0.0007 10 0 0 0 1.46E+07 4.32E+06 - - - 1.9838 0.9998 221125_WJC_METTL3_EV_vs_WT_F07.07781.07781.2 3.60E-06 22-Nov R.QDYASTSASVSR.H "sp|Q8ND83|SLAI1_HUMAN,tr|X6RGK9|X6RGK9_HUMAN,tr|B7Z326|B7Z326_HUMAN,tr|C9JUW9|C9JUW9_HUMAN,tr|X6RDJ2|X6RDJ2_HUMAN,tr|C9JP03|C9JP03_HUMAN,tr|Q5T6P2|Q5T6P2_HUMAN,tr|A0A0A0MSS3|A0A0A0MSS3_HUMAN,tr|Q5T6P1|Q5T6P1_HUMAN,tr|A0A0C4DFN6|A0A0C4DFN6_HUMAN,tr|C9JD09|C9JD09_HUMAN" 11 1270.579 1.2 96137 7781 2 1270.580849 636.2968 SLAIN motif-containing protein 1 OS=Homo sapiens OX=9606 GN=SLAIN1 PE=1 SV=3 5.84 1775.8 - 1.18E+06 - - - 1.4875 - 2.17 0.548 - 397.8 1 2 0 0.0019 12 0 0 0 1.25E+07 1.05E+07 - - - 5.1264 0.9999 221125_WJC_METTL3_EV_vs_WT_F07.07782.07782.2 4.07E-06 22-Dec R.QDYASTSASVSR[166.11].H "sp|Q8ND83|SLAI1_HUMAN,tr|X6RGK9|X6RGK9_HUMAN,tr|B7Z326|B7Z326_HUMAN,tr|C9JUW9|C9JUW9_HUMAN,tr|X6RDJ2|X6RDJ2_HUMAN,tr|C9JP03|C9JP03_HUMAN,tr|Q5T6P2|Q5T6P2_HUMAN,tr|A0A0A0MSS3|A0A0A0MSS3_HUMAN,tr|Q5T6P1|Q5T6P1_HUMAN,tr|A0A0C4DFN6|A0A0C4DFN6_HUMAN,tr|C9JD09|C9JD09_HUMAN" 11 1280.5872 1.2 96138 7782 2 1280.587624 641.3009 SLAIN motif-containing protein 1 OS=Homo sapiens OX=9606 GN=SLAIN1 PE=1 SV=3 5.84 1775.9 - 847000 - - - 0.3085 - 2.125 0.61 - 526.9 1 2 0 0.0004 12 0 0 0 1.25E+07 1.05E+07 - - - 5.5296 0.9997 221125_WJC_METTL3_EV_vs_WT_F07.07783.07783.3 0.0187 Dec-40 K.EETQPPVALK[136.11]K[136.11].E sp|Q8NC51|PAIRB_HUMAN 1 1254.7155 0.8 96139 7783 3 1254.716713 419.2458 Plasminogen activator inhibitor 1 RNA-binding protein OS=Homo sapiens OX=9606 GN=SERBP1 PE=1 SV=2 6.24 1775.9 - 2.81E+06 - - - 1.0042 - 1.975 0.343 - 253.3 1 2 0 0.0013 11 0 0 0 1.59E+09 2.00E+09 - - - 4.2971 0.9961 221125_WJC_METTL3_EV_vs_WT_F07.07784.07784.3 7.40E-05 Aug-44 K.SRAEAALEEESR.Q "sp|Q969G3|SMCE1_HUMAN,tr|A0A2R8Y855|A0A2R8Y855_HUMAN,tr|A0A2R8YES3|A0A2R8YES3_HUMAN,tr|A0A2U3TZQ7|A0A2U3TZQ7_HUMAN,tr|A0A2R8Y7U4|A0A2R8Y7U4_HUMAN,tr|B4DGM3|B4DGM3_HUMAN,tr|A0A2R8YD78|A0A2R8YD78_HUMAN,tr|J3QKS7|J3QKS7_HUMAN,tr|A0A2R8Y4T4|A0A2R8Y4T4_HUMAN,tr|A0A2R8Y7I9|A0A2R8Y7I9_HUMAN,tr|J3QR61|J3QR61_HUMAN,tr|A0A2R8Y765|A0A2R8Y765_HUMAN,tr|J3KT85|J3KT85_HUMAN" 13 1346.6426 2.09 96140 7784 3 1346.642291 449.8882 SWI\SNF-related matrix-associated actin-dependent regulator of chromatin subfamily E member 1 OS=Homo sapiens OX=9606 GN=SMARCE1 PE=1 SV=2 4.49 1776 - 1.49E+06 - - - -0.2458 - 2.208 0.242 - 131.1 1 2 1 -0.0003 12 0 0 0 3.33E+07 1.59E+07 - - - 3.4335 0.9942 221125_WJC_METTL3_EV_vs_WT_F07.07785.07785.3 0.0773 Sep-36 K.EGVKFDESEK.T "sp|P14625|ENPL_HUMAN,tr|A0A7P0T917|A0A7P0T917_HUMAN,tr|A0A7P0T823|A0A7P0T823_HUMAN,tr|A0A7P0TAE1|A0A7P0TAE1_HUMAN,tr|H0YIV0|H0YIV0_HUMAN,tr|A0A7P0TAY2|A0A7P0TAY2_HUMAN,tr|A0A087WT78|A0A087WT78_HUMAN,tr|A0A7P0TAT8|A0A7P0TAT8_HUMAN" 8 1166.5455 0.66 96141 7785 3 1166.544624 389.8558 Endoplasmin OS=Homo sapiens OX=9606 GN=HSP90B1 PE=1 SV=1 4.41 1776.1 - 672851 - - - -0.7792 - 1.691 0.275 - 81.9 1 2 1 -0.0009 10 0 0 0 1.36E+07 2.04E+07 - - - 3.1399 0.9983 221125_WJC_METTL3_EV_vs_WT_F07.07787.07787.2 8.11E-06 14/22 K.SRAEAALEEESR.Q "sp|Q969G3|SMCE1_HUMAN,tr|A0A2R8Y855|A0A2R8Y855_HUMAN,tr|A0A2R8YES3|A0A2R8YES3_HUMAN,tr|A0A2U3TZQ7|A0A2U3TZQ7_HUMAN,tr|A0A2R8Y7U4|A0A2R8Y7U4_HUMAN,tr|B4DGM3|B4DGM3_HUMAN,tr|A0A2R8YD78|A0A2R8YD78_HUMAN,tr|J3QKS7|J3QKS7_HUMAN,tr|A0A2R8Y4T4|A0A2R8Y4T4_HUMAN,tr|A0A2R8Y7I9|A0A2R8Y7I9_HUMAN,tr|J3QR61|J3QR61_HUMAN,tr|A0A2R8Y765|A0A2R8Y765_HUMAN,tr|J3KT85|J3KT85_HUMAN" 13 1346.6426 2.39 96143 7787 2 1346.644067 674.3286 SWI\SNF-related matrix-associated actin-dependent regulator of chromatin subfamily E member 1 OS=Homo sapiens OX=9606 GN=SMARCE1 PE=1 SV=2 4.49 1776.3 - 398438 - - - 1.073 - 3.083 0.414 - 273.9 1 2 1 0.0014 12 0 0 0 1.14E+07 4.78E+06 - - - 5.0608 0.9982 221125_WJC_METTL3_EV_vs_WT_F07.07788.07788.2 0.000109 14/22 K.SR[166.11]AEAALEEESR[166.11].Q "sp|Q969G3|SMCE1_HUMAN,tr|A0A2R8Y855|A0A2R8Y855_HUMAN,tr|A0A2R8YES3|A0A2R8YES3_HUMAN,tr|A0A2U3TZQ7|A0A2U3TZQ7_HUMAN,tr|A0A2R8Y7U4|A0A2R8Y7U4_HUMAN,tr|B4DGM3|B4DGM3_HUMAN,tr|A0A2R8YD78|A0A2R8YD78_HUMAN,tr|J3QKS7|J3QKS7_HUMAN,tr|A0A2R8Y4T4|A0A2R8Y4T4_HUMAN,tr|A0A2R8Y7I9|A0A2R8Y7I9_HUMAN,tr|J3QR61|J3QR61_HUMAN,tr|A0A2R8Y765|A0A2R8Y765_HUMAN,tr|J3KT85|J3KT85_HUMAN" 13 1366.6592 2.39 96144 7788 2 1366.660256 684.3369 SWI\SNF-related matrix-associated actin-dependent regulator of chromatin subfamily E member 1 OS=Homo sapiens OX=9606 GN=SMARCE1 PE=1 SV=2 4.49 1776.5 - 255870 - - - 0.8005 - 2.964 0.384 - 253.4 1 2 1 0.0011 12 0 0 0 1.14E+07 4.78E+06 - - - 4.7358 0.9998 221125_WJC_METTL3_EV_vs_WT_F07.07793.07793.3 0.000211 16/48 R.LAQDGAHVVVSSR.K "sp|Q9BTZ2|DHRS4_HUMAN,tr|F5GWZ1|F5GWZ1_HUMAN" 2 1337.7052 1.49 96148 7793 3 1337.708468 446.909 Dehydrogenase\reductase SDR family member 4 OS=Homo sapiens OX=9606 GN=DHRS4 PE=1 SV=3 6.74 1777 - 1.14E+06 - - - 2.4714 - 2.893 0.368 - 370.5 1 2 0 0.0033 13 0 0 0 1.94E+08 1.31E+08 - - - 5.5221 0.9928 221125_WJC_METTL3_EV_vs_WT_F07.07795.07795.3 6.15E-06 13/44 H.TSDEQNHLVVAR[166.11].V "sp|Q16576|RBBP7_HUMAN,tr|C9J7L0|C9J7L0_HUMAN,tr|E9PC52|E9PC52_HUMAN" 3 1377.6876 1.45 96150 7795 3 1377.690172 460.2365 Histone-binding protein RBBP7 OS=Homo sapiens OX=9606 GN=RBBP7 PE=1 SV=1 5.29 1777.2 - 653112 - - - 1.8589 - 2.191 0.491 - 219.2 1 1 0 0.0026 12 0 0 0 8.70E+06 6.01E+06 - - - 6.1876 0.9984 221125_WJC_METTL3_EV_vs_WT_F07.07797.07797.3 0.000136 Nov-56 R.MGPGAASGGER[166.11]PNLK[136.11].L "sp|Q9H0U4|RAB1B_HUMAN,sp|Q92928|RAB1C_HUMAN,tr|E9PLD0|E9PLD0_HUMAN" 3 1458.7368 1.16 96152 7797 3 1458.740574 487.2529 Ras-related protein Rab-1B OS=Homo sapiens OX=9606 GN=RAB1B PE=1 SV=1 8.5 1777.5 - 313217 - - - 2.5755 - 2.291 0.273 - 133.7 1 2 0 0.0038 15 0 0 0 3.27E+08 2.82E+08 - - - 3.7458 0.9999 221125_WJC_METTL3_EV_vs_WT_F07.07798.07798.2 2.88E-07 26-Oct R.SGDETPGSEVPGDK.A "sp|Q1KMD3|HNRL2_HUMAN,tr|H3BQZ7|H3BQZ7_HUMAN" 2 1373.5947 1.15 96153 7798 2 1373.595684 687.8046 Heterogeneous nuclear ribonucleoprotein U-like protein 2 OS=Homo sapiens OX=9606 GN=HNRNPUL2 PE=1 SV=1 3.92 1777.6 - 246144 - - - 0.7397 - 2.236 0.599 - 239.5 1 2 0 0.001 14 0 0 0 2.76E+06 2.40E+06 - - - 5.4842 0.9965 221125_WJC_METTL3_EV_vs_WT_F07.07799.07799.2 0.00316 20-Jul K.EETQPPVALKK.E sp|Q8NC51|PAIRB_HUMAN 1 1238.6871 0.82 96154 7799 2 1238.688357 620.3508 Plasminogen activator inhibitor 1 RNA-binding protein OS=Homo sapiens OX=9606 GN=SERBP1 PE=1 SV=2 6.24 1777.7 - 211730 - - - 1.0527 - 1.352 0.235 - 117.4 1 2 0 0.0013 11 0 0 0 2.10E+08 2.58E+08 - - - 1.5922 0.9846 221125_WJC_METTL3_EV_vs_WT_F07.07800.07800.2 0.00601 26-Nov L.EGGQEDFESSGAGK.L "sp|P35527|K1C9_HUMAN,tr|K7EQQ3|K7EQQ3_HUMAN" 2 1396.5743 999 96155 7800 2 1396.576827 699.2944 "Keratin, type I cytoskeletal 9 OS=Homo sapiens OX=9606 GN=KRT9 PE=1 SV=3" 4 1777.8 - 191670 - - - 1.8331 - 2.067 0.534 - 359.1 1 1 0 0.0026 14 0 0 0 1.72E+06 0.00E+00 - - - 4.8064 0.9936 221125_WJC_METTL3_EV_vs_WT_F07.07801.07801.2 0.0108 20-Jun K.GK[136.11]DAFPVAGQK[136.11].L "sp|P54727|RD23B_HUMAN,tr|Q5W0S4|Q5W0S4_HUMAN,tr|Q5W0S5|Q5W0S5_HUMAN" 3 1132.6212 1.48 96156 7801 2 1132.62148 567.3179 UV excision repair protein RAD23 homolog B OS=Homo sapiens OX=9606 GN=RAD23B PE=1 SV=1 8.59 1778 - 134714 - - - 0.2843 - 1.304 0.427 - 87.3 1 2 1 0.0003 11 0 0 0 2.00E+06 1.35E+06 - - - 2.9128 0.9914 221125_WJC_METTL3_EV_vs_WT_F07.07802.07802.2 1.48E-05 16-Sep T.TAC[160.03]QHVFC[160.03]R[166.11].K "sp|Q8WVD3|RN138_HUMAN,tr|J3QKM8|J3QKM8_HUMAN,tr|J3KSI2|J3KSI2_HUMAN" 3 1187.5204 3.05 96157 7802 2 1187.521272 594.7675 E3 ubiquitin-protein ligase RNF138 OS=Homo sapiens OX=9606 GN=RNF138 PE=1 SV=1 7.78 1778.1 - 123394 - - - 0.7747 - 1.757 0.569 - 449.3 1 1 0 0.0009 9 0 0 0 2.64E+06 8.63E+05 - - - 4.8739 0.9999 221125_WJC_METTL3_EV_vs_WT_F07.07808.07808.3 3.89E-06 13/52 K.LHDSSGSQVGTGFK[136.11].S sp|P49792|RBP2_HUMAN 1 1426.6932 1 96161 7808 3 1426.696475 476.5717 E3 SUMO-protein ligase RanBP2 OS=Homo sapiens OX=9606 GN=RANBP2 PE=1 SV=2 6.74 1778.8 - 1.31E+06 - - - 2.2906 - 2.131 0.52 - 222.5 1 2 0 0.0033 14 0 0 0 2.27E+07 2.26E+07 - - - 6.3472 0.9992 221125_WJC_METTL3_EV_vs_WT_F07.07810.07810.2 0.00112 16-Sep K.QDSGHLDLR[166.11].N "sp|Q86U44|MTA70_HUMAN,tr|B4E349|B4E349_HUMAN,tr|F5H6D8|F5H6D8_HUMAN,tr|B4DTN4|B4DTN4_HUMAN" 4 1049.5129 -1 96163 7810 2 1049.515254 525.7637 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 5.21 1779 - 678096 - - - 2.2039 - 1.762 0.398 - 253.8 1 2 0 0.0023 9 0 0 0 0.00E+00 0.00E+00 - - - 3.6187 0.9999 221125_WJC_METTL3_EV_vs_WT_F07.07811.07811.3 3.79E-08 14/48 K.LEDYDKAETEASK.A "sp|Q9H3U1|UN45A_HUMAN,tr|A0A1W2PNX8|A0A1W2PNX8_HUMAN" 2 1497.6835 0.5 96164 7811 3 1497.683932 500.2351 Protein unc-45 homolog A OS=Homo sapiens OX=9606 GN=UNC45A PE=1 SV=1 4.18 1779.1 - 525045 - - - 0.2998 - 2.571 0.574 - 306.4 1 2 1 0.0004 13 0 0 0 4.00E+06 8.07E+06 - - - 7.4997 0.9964 221125_WJC_METTL3_EV_vs_WT_F07.07812.07812.2 0.00524 20-Aug K.EETQPPVALK[136.11]K[136.11].E sp|Q8NC51|PAIRB_HUMAN 1 1254.7155 0.82 96165 7812 2 1254.717554 628.365 Plasminogen activator inhibitor 1 RNA-binding protein OS=Homo sapiens OX=9606 GN=SERBP1 PE=1 SV=2 6.24 1779.2 - 347908 - - - 1.6745 - 1.338 0.27 - 149.4 1 2 0 0.0021 11 0 0 0 2.09E+08 2.56E+08 - - - 1.8223 0.9858 221125_WJC_METTL3_EV_vs_WT_F07.07813.07813.2 0.00127 22-Aug R.IISSIEQK[136.11]EENK[136.11].G "sp|P62258|1433E_HUMAN,tr|B4DJF2|B4DJF2_HUMAN,tr|I3L3T1|I3L3T1_HUMAN,tr|K7EIT4|K7EIT4_HUMAN" 4 1432.7744 1.11 96166 7813 2 1432.775992 717.3945 14-3-3 protein epsilon OS=Homo sapiens OX=9606 GN=YWHAE PE=1 SV=1 4.79 1779.3 - 206470 - - - 1.0944 - 1.502 0.315 - 141.6 1 2 1 0.0016 12 0 0 0 1.83E+06 1.65E+06 - - - 2.4375 0.8613 221125_WJC_METTL3_EV_vs_WT_F07.07815.07815.2 0.00086 16-Aug T.TAC[160.03]QHVFC[160.03]R.K "sp|Q8WVD3|RN138_HUMAN,tr|J3QKM8|J3QKM8_HUMAN,tr|J3KSI2|J3KSI2_HUMAN" 3 1177.5121 3.09 96168 7815 2 1177.516649 589.7633 E3 ubiquitin-protein ligase RNF138 OS=Homo sapiens OX=9606 GN=RNF138 PE=1 SV=1 7.78 1779.6 - 128625 - - - 3.8785 - 1.432 0.47 - 219.5 1 1 0 0.0046 9 0 0 0 2.67E+06 8.63E+05 - - - 3.5498 0.9999 221125_WJC_METTL3_EV_vs_WT_F07.07816.07816.2 2.98E-05 20-Nov R.K[136.11]PEVTC[160.03]TLEDK[136.11].K "sp|Q96EI5|TCAL4_HUMAN,tr|D6RD44|D6RD44_HUMAN,tr|D6RCE9|D6RCE9_HUMAN,tr|J3KQY4|J3KQY4_HUMAN,tr|A2RQR6|A2RQR6_HUMAN,tr|D6RIH3|D6RIH3_HUMAN,tr|D6RHZ1|D6RHZ1_HUMAN" 7 1334.6723 1.41 96169 7816 2 1334.672523 668.3434 Transcription elongation factor A protein-like 4 OS=Homo sapiens OX=9606 GN=TCEAL4 PE=1 SV=2 4.68 1779.7 - 116601 - - - 0.1918 - 2.352 0.565 - 489 1 2 0 0.0003 11 0 0 0 1.86E+07 1.32E+07 - - - 5.5277 0.9999 221125_WJC_METTL3_EV_vs_WT_F07.07821.07821.3 1.89E-06 13/36 R.TTAC[160.03]QHVFC[160.03]R.K "sp|Q8WVD3|RN138_HUMAN,tr|J3QKM8|J3QKM8_HUMAN,tr|J3KSI2|J3KSI2_HUMAN" 3 1278.5598 1.29 96173 7821 3 1278.562826 427.1939 E3 ubiquitin-protein ligase RNF138 OS=Homo sapiens OX=9606 GN=RNF138 PE=1 SV=1 7.78 1780.4 - 3.02E+06 - - - 2.3972 - 2.198 0.448 - 390 1 2 0 0.0031 10 0 0 0 6.04E+07 4.69E+07 - - - 5.8339 0.9958 221125_WJC_METTL3_EV_vs_WT_F07.07822.07822.3 0.0268 Jul-52 R.QSLGHPPPEPGPDR.V "sp|P13861|KAP2_HUMAN,tr|C9J830|C9J830_HUMAN" 2 1482.7215 2.31 96174 7822 3 1482.725501 495.2478 cAMP-dependent protein kinase type II-alpha regulatory subunit OS=Homo sapiens OX=9606 GN=PRKAR2A PE=1 SV=2 5.32 1780.5 - 1.68E+06 - - - 2.6708 - 1.764 0.284 - 53.8 2 2 0 0.004 14 0 0 0 7.31E+07 3.16E+07 - - - 3.0743 0.8265 221125_WJC_METTL3_EV_vs_WT_F07.07824.07824.2 1.69 12-Sep D.SGHLDLR[166.11].N "sp|Q86U44|MTA70_HUMAN,tr|D6R9M9|D6R9M9_HUMAN,tr|B4E349|B4E349_HUMAN,tr|F5H6D8|F5H6D8_HUMAN,tr|B4DTN4|B4DTN4_HUMAN,tr|D6R9X6|D6R9X6_HUMAN" 6 806.4274 0.02 96176 7824 2 806.429154 404.221 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 6.46 1780.6 - 1.38E+06 - - - 2.149 - 1.527 0.233 - 386.2 1 1 0 0.0017 7 0 0 0 6.35E+07 2.74E+09 - - - 2.1027 0.9693 221125_WJC_METTL3_EV_vs_WT_F07.07826.07826.3 0.0142 Jul-44 R.EKAEGDVAALNR.R "sp|P67936|TPM4_HUMAN,tr|A0A2R8Y5V9|A0A2R8Y5V9_HUMAN,tr|A0A2R8YGX3|A0A2R8YGX3_HUMAN,tr|A0A2R8YH90|A0A2R8YH90_HUMAN" 4 1271.647 0.67 96178 7826 3 1271.648626 424.8896 Tropomyosin alpha-4 chain OS=Homo sapiens OX=9606 GN=TPM4 PE=1 SV=3 4.68 1780.8 - 695055 - - - 1.2952 - 1.536 0.221 - 77.8 1 2 1 0.0016 12 0 0 0 1.05E+07 1.58E+07 - - - 2.1931 0.9994 221125_WJC_METTL3_EV_vs_WT_F07.07827.07827.3 0.00203 Nov-52 R.ALER[166.11]DPTEDDVESK[136.11].K "sp|Q86YP4|P66A_HUMAN,tr|V9GY85|V9GY85_HUMAN,tr|V9GYX5|V9GYX5_HUMAN,tr|C9JJK9|C9JJK9_HUMAN,tr|H7C3H1|H7C3H1_HUMAN,tr|C9JVY3|C9JVY3_HUMAN,tr|C9JMI3|C9JMI3_HUMAN,tr|C9JGN4|C9JGN4_HUMAN" 8 1620.7598 1.79 96179 7827 3 1620.763498 541.2605 Transcriptional repressor p66-alpha OS=Homo sapiens OX=9606 GN=GATAD2A PE=1 SV=1 4.02 1780.9 - 392116 - - - 2.294 - 2.398 0.441 - 137.3 1 2 1 0.0037 14 0 0 0 1.53E+07 8.55E+06 - - - 5.7801 1 221125_WJC_METTL3_EV_vs_WT_F07.07828.07828.2 3.23E-08 22-Dec R.GQVSESEDSITK[136.11].Q sp|O95239|KIF4A_HUMAN 1 1286.6081 0.4 96180 7828 2 1286.608619 644.3113 Chromosome-associated kinesin KIF4A OS=Homo sapiens OX=9606 GN=KIF4A PE=1 SV=3 4.14 1781 - 379754 - - - 0.3723 - 2.554 0.625 - 400.5 1 2 0 0.0005 12 0 0 0 2.18E+06 5.40E+06 - - - 6.1242 0.993 221125_WJC_METTL3_EV_vs_WT_F07.07830.07830.2 4.51E-09 16/28 S.GGGGGGGLGSGGSIR.S sp|P35527|K1C9_HUMAN 1 1144.5585 333.33 96182 7830 2 1144.559385 573.2865 "Keratin, type I cytoskeletal 9 OS=Homo sapiens OX=9606 GN=KRT9 PE=1 SV=3" 9.75 1781.3 - 293221 - - - 0.775 - 3.036 0.475 - 744.3 1 1 0 0.0009 15 0 0 0 3.79E+07 1.14E+05 - - - 5.2794 0.9199 221125_WJC_METTL3_EV_vs_WT_F07.07835.07835.2 1.05 14-Aug Q.DSGHLDLR[166.11].N "sp|Q86U44|MTA70_HUMAN,tr|B4E349|B4E349_HUMAN,tr|F5H6D8|F5H6D8_HUMAN,tr|B4DTN4|B4DTN4_HUMAN" 4 921.4544 0.02 96185 7835 2 921.454732 461.7345 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 5.21 1781.9 - 1.11E+07 - - - 0.3994 - 1.912 0.15 - 253.3 1 1 0 0.0004 8 0 0 0 1.03E+08 4.25E+09 - - - 2.1036 0.9999 221125_WJC_METTL3_EV_vs_WT_F07.07841.07841.2 0.0134 18-Nov R.DHALLEEQSK.Q "sp|O43707|ACTN4_HUMAN,tr|F5GXS2|F5GXS2_HUMAN,tr|H7C144|H7C144_HUMAN" 3 1168.5724 2.47 96191 7841 2 1168.573345 585.2935 Alpha-actinin-4 OS=Homo sapiens OX=9606 GN=ACTN4 PE=1 SV=2 4.65 1782.5 - 456640 - - - 0.7941 - 2.335 0.474 - 512.5 1 2 0 0.0009 10 0 0 0 9.03E+06 3.66E+06 - - - 4.9087 0.989 221125_WJC_METTL3_EV_vs_WT_F07.07846.07846.2 0.00358 16-Sep K.QDSGHLDLR.N "sp|Q86U44|MTA70_HUMAN,tr|B4E349|B4E349_HUMAN,tr|F5H6D8|F5H6D8_HUMAN,tr|B4DTN4|B4DTN4_HUMAN" 4 1039.5047 0.02 96194 7846 2 1039.497926 520.7596 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 5.21 1783 - 1.12E+06 - - - -6.4887 - 1.987 0.409 - 274.5 1 2 0 -0.0067 9 0 0 0 4.56E+08 1.93E+10 - - - 4.0462 0.9996 221125_WJC_METTL3_EV_vs_WT_F07.07848.07848.2 0.123 18-Sep R.DHALLEEQSK[136.11].Q "sp|O43707|ACTN4_HUMAN,tr|F5GXS2|F5GXS2_HUMAN,tr|H7C144|H7C144_HUMAN" 3 1176.5866 2.47 96196 7848 2 1176.584303 589.3006 Alpha-actinin-4 OS=Homo sapiens OX=9606 GN=ACTN4 PE=1 SV=2 4.65 1783.3 - 488165 - - - -1.9667 - 1.979 0.431 - 308.1 1 2 0 -0.0023 10 0 0 0 9.03E+06 3.66E+06 - - - 4.129 0.919 221125_WJC_METTL3_EV_vs_WT_F07.07868.07868.2 0.0222 14-Oct Q.DSGHLDLR.N "sp|Q86U44|MTA70_HUMAN,tr|B4E349|B4E349_HUMAN,tr|F5H6D8|F5H6D8_HUMAN,tr|B4DTN4|B4DTN4_HUMAN" 4 911.4461 0.02 96207 7868 2 911.443638 456.7303 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 5.21 1785.9 - 2.00E+06 - - - -2.6946 - 2.184 0.248 - 381 1 1 0 -0.0025 8 0 0 0 1.03E+08 4.25E+09 - - - 3.2279 0.9972 221125_WJC_METTL3_EV_vs_WT_F07.07869.07869.3 0.0274 Dec-32 K.HVVFIAQR[166.11]R[166.11].L "sp|P62081|RS7_HUMAN,tr|B5MCP9|B5MCP9_HUMAN,tr|A0A2R8Y623|A0A2R8Y623_HUMAN" 3 1144.6732 0.001 96208 7869 3 1144.670218 382.565 40S ribosomal protein S7 OS=Homo sapiens OX=9606 GN=RPS7 PE=1 SV=1 12 1786.1 - 1.65E+06 - - - -2.6366 - 1.773 0.274 - 119.6 1 2 0 -0.003 9 0 0 0 0.00E+00 3.75E+07 - - - 3.3199 1 221125_WJC_METTL3_EV_vs_WT_F07.07870.07870.3 2.13E-08 17/48 L.TTSAGIMDHEEAR[166.11].R sp|P62244|RS15A_HUMAN 1 1426.6386 0.83 96209 7870 3 1426.636693 476.5535 40S ribosomal protein S15a OS=Homo sapiens OX=9606 GN=RPS15A PE=1 SV=2 4.65 1786.2 - 1.25E+06 - - - -1.3451 - 3.124 0.633 - 470.2 1 1 0 -0.0019 13 0 0 0 7.17E+07 8.63E+07 - - - 8.6853 1 221125_WJC_METTL3_EV_vs_WT_F07.07877.07877.3 2.19E-06 19/48 L.TTSAGIMDHEEAR.R sp|P62244|RS15A_HUMAN 1 1416.6303 0.83 96213 7877 3 1416.62776 473.2174 40S ribosomal protein S15a OS=Homo sapiens OX=9606 GN=RPS15A PE=1 SV=2 4.65 1787.1 - 1.87E+06 - - - -1.8226 - 3.411 0.646 - 581 1 1 0 -0.0026 13 0 0 0 7.17E+07 8.63E+07 - - - 9.0683 0.9963 221125_WJC_METTL3_EV_vs_WT_F07.07891.07891.2 0.000301 26-Dec K.SNTAGSQSQVETEA.- sp|Q02790|FKBP4_HUMAN 1 1407.6114 - 96221 7891 2 1407.604377 704.813 Peptidyl-prolyl cis-trans isomerase FKBP4 OS=Homo sapiens OX=9606 GN=FKBP4 PE=1 SV=3 3.79 1788.7 - 1.42E+06 - - - -4.9758 - 2.023 0.446 - 334.4 1 2 0 -0.007 14 0 0 0 - - - - - 4.1011 0.9999 221125_WJC_METTL3_EV_vs_WT_F07.07894.07894.3 4.87E-06 15/56 R.MGPGAASGGERPNLK.L "sp|Q9H0U4|RAB1B_HUMAN,sp|Q92928|RAB1C_HUMAN,tr|E9PLD0|E9PLD0_HUMAN" 3 1440.7143 1.15 96223 7894 3 1440.710489 481.2454 Ras-related protein Rab-1B OS=Homo sapiens OX=9606 GN=RAB1B PE=1 SV=1 8.5 1789 - 8.49E+06 - - - -2.6778 - 2.594 0.507 - 226.2 1 2 0 -0.0039 15 0 0 0 3.23E+08 2.82E+08 - - - 6.6787 0.9931 221125_WJC_METTL3_EV_vs_WT_F07.07897.07897.3 0.0013 Nov-40 R.KPEVTC[160.03]TLEDK.K "sp|Q96EI5|TCAL4_HUMAN,tr|D6RD44|D6RD44_HUMAN,tr|D6RCE9|D6RCE9_HUMAN,tr|J3KQY4|J3KQY4_HUMAN,tr|A2RQR6|A2RQR6_HUMAN,tr|D6RIH3|D6RIH3_HUMAN,tr|D6RHZ1|D6RHZ1_HUMAN" 7 1318.6439 4.53 96224 7897 3 1318.639192 440.5552 Transcription elongation factor A protein-like 4 OS=Homo sapiens OX=9606 GN=TCEAL4 PE=1 SV=2 4.68 1789.3 - 1.28E+06 - - - -3.5453 - 1.941 0.245 - 223.7 1 2 0 -0.0047 11 0 0 0 1.43E+08 3.16E+07 - - - 3.1543 0.9999 221125_WJC_METTL3_EV_vs_WT_F07.07908.07908.3 1.42E-07 13/40 R.K[136.11]PVEELTEEEK[136.11].Y "sp|Q9Y2R9|RT07_HUMAN,tr|J3QKW2|J3QKW2_HUMAN,tr|J3QLS3|J3QLS3_HUMAN" 3 1345.6948 1.22 96230 7908 3 1345.691994 449.5722 "28S ribosomal protein S7, mitochondrial OS=Homo sapiens OX=9606 GN=MRPS7 PE=1 SV=2" 4.33 1790.6 - 1.49E+06 - - - -2.0681 - 2.548 0.477 - 395.4 1 2 0 -0.0028 11 0 0 0 3.88E+07 3.18E+07 - - - 6.5144 0.9983 221125_WJC_METTL3_EV_vs_WT_F07.07909.07909.2 1.82E-05 20-Nov K.GSQTEFEQQER[166.11].L "sp|Q96EA4|SPDLY_HUMAN,tr|H0YBG5|H0YBG5_HUMAN" 2 1347.593 0.24 96231 7909 2 1347.587468 674.8038 Protein Spindly OS=Homo sapiens OX=9606 GN=SPDL1 PE=1 SV=2 4.25 1790.8 - 1.19E+06 - - - -4.1363 - 2.137 0.447 - 577.2 1 2 0 -0.0056 11 0 0 0 7.85E+06 3.26E+07 - - - 4.3952 0.8282 221125_WJC_METTL3_EV_vs_WT_F07.07910.07910.2 0.254 14-Aug R.STLEPVEK[136.11].A "sp|P48741|HSP77_HUMAN,sp|P0DMV8|HS71A_HUMAN,sp|P0DMV9|HS71B_HUMAN,sp|P17066|HSP76_HUMAN,tr|V9GZ37|V9GZ37_HUMAN,tr|A0A0G2JIW1|A0A0G2JIW1_HUMAN" 6 909.4899 0.04 96232 7910 2 909.485501 455.7522 Putative heat shock 70 kDa protein 7 OS=Homo sapiens OX=9606 GN=HSPA7 PE=5 SV=2 4.53 1790.9 - 2.51E+06 - - - -4.7961 - 1.348 0.073 - 203.2 1 2 0 -0.0044 8 0 0 0 7.97E+05 2.09E+07 - - - 0.4794 0.9991 221125_WJC_METTL3_EV_vs_WT_F07.07915.07915.3 0.0169 14/40 K.EETQPPVALKK[136.11].E sp|Q8NC51|PAIRB_HUMAN 1 1246.7013 - 96234 7915 3 1246.700933 416.5744 Plasminogen activator inhibitor 1 RNA-binding protein OS=Homo sapiens OX=9606 GN=SERBP1 PE=1 SV=2 6.24 1791.5 - 2.00E+06 - - - -0.2567 - 1.815 0.285 - 222.5 1 2 0 -0.0003 11 0 0 0 - - - - - 3.4108 0.9997 221125_WJC_METTL3_EV_vs_WT_F07.07917.07917.2 0.000159 19/20 R.KPVEELTEEEK.Y "sp|Q9Y2R9|RT07_HUMAN,tr|J3QKW2|J3QKW2_HUMAN,tr|J3QLS3|J3QLS3_HUMAN" 3 1329.6664 1.21 96236 7917 2 1329.663018 665.8405 "28S ribosomal protein S7, mitochondrial OS=Homo sapiens OX=9606 GN=MRPS7 PE=1 SV=2" 4.33 1791.8 - 1.46E+06 - - - -2.5262 - 3.17 0.443 - 1121.3 1 2 0 -0.0034 11 0 0 0 3.64E+07 3.01E+07 - - - 5.4331 0.9599 221125_WJC_METTL3_EV_vs_WT_F07.07926.07926.3 0.505 Dec-40 R.KPVEELTEEEK.Y "sp|Q9Y2R9|RT07_HUMAN,tr|J3QKW2|J3QKW2_HUMAN,tr|J3QLS3|J3QLS3_HUMAN" 3 1329.6664 1.21 96240 7926 3 1329.669981 444.2294 "28S ribosomal protein S7, mitochondrial OS=Homo sapiens OX=9606 GN=MRPS7 PE=1 SV=2" 4.33 1793 - 1.43E+06 - - - 2.7105 - 1.453 0.183 - 144.6 1 2 0 0.0036 11 0 0 0 3.90E+07 3.22E+07 - - - 1.6407 0.9999 221125_WJC_METTL3_EV_vs_WT_F07.07927.07927.2 8.85E-05 15/20 R.K[136.11]PVEELTEEEK[136.11].Y "sp|Q9Y2R9|RT07_HUMAN,tr|J3QKW2|J3QKW2_HUMAN,tr|J3QLS3|J3QLS3_HUMAN" 3 1345.6948 1.21 96241 7927 2 1345.6957 673.8547 "28S ribosomal protein S7, mitochondrial OS=Homo sapiens OX=9606 GN=MRPS7 PE=1 SV=2" 4.33 1793.2 - 598134 - - - 0.6859 - 2.682 0.481 - 903.1 1 2 0 0.0009 11 0 0 0 3.64E+07 3.01E+07 - - - 5.2623 0.9932 221125_WJC_METTL3_EV_vs_WT_F07.07929.07929.3 0.00103 Dec-44 R.GGGQEERPFVAR.F "sp|Q9HA64|KT3K_HUMAN,tr|I3L2G3|I3L2G3_HUMAN" 2 1301.6476 0.66 96243 7929 3 1301.646953 434.8898 Ketosamine-3-kinase OS=Homo sapiens OX=9606 GN=FN3KRP PE=1 SV=2 6.14 1793.3 - 1.42E+06 - - - -0.5332 - 2.075 0.133 - 293.7 1 2 0 -0.0007 12 0 0 0 7.61E+07 1.16E+08 - - - 2.046 0.9997 221125_WJC_METTL3_EV_vs_WT_F07.07934.07934.2 1.49 18-Dec R.K[136.11]QEELVQQVR[166.11].K "sp|O95983|MBD3_HUMAN,tr|K7EIE8|K7EIE8_HUMAN" 2 1273.7109 1.18 96245 7934 2 1273.709074 637.8627 Methyl-CpG-binding domain protein 3 OS=Homo sapiens OX=9606 GN=MBD3 PE=1 SV=1 6.14 1793.9 - 673516 - - - -1.4493 - 2.604 0.306 - 615.5 1 2 0 -0.0018 10 0 0 0 5.93E+07 5.03E+07 - - - 3.972 0.9996 221125_WJC_METTL3_EV_vs_WT_F07.07940.07940.3 0.125 Oct-36 R.K[136.11]QEELVQQVR[166.11].K "sp|O95983|MBD3_HUMAN,tr|K7EIE8|K7EIE8_HUMAN" 2 1273.7109 1.02 96248 7940 3 1273.70853 425.5776 Methyl-CpG-binding domain protein 3 OS=Homo sapiens OX=9606 GN=MBD3 PE=1 SV=1 6.14 1794.7 - 4.77E+06 - - - -1.8764 - 2.311 0.307 - 194 1 2 0 -0.0024 10 0 0 0 2.56E+08 2.51E+08 - - - 4.4085 0.9997 221125_WJC_METTL3_EV_vs_WT_F07.07941.07941.2 0.0351 16-Aug K.SETINC[160.03]HFK.S sp|O75635|SPB7_HUMAN 1 1134.5128 999 96249 7941 2 1134.511643 568.2637 Serpin B7 OS=Homo sapiens OX=9606 GN=SERPINB7 PE=1 SV=1 6.46 1794.8 - 339087 - - - -1.0145 - 2.096 0.337 - 335 1 2 0 -0.0011 9 0 0 0 5.15E+06 0.00E+00 - - - 3.6707 0.9986 221125_WJC_METTL3_EV_vs_WT_F07.07949.07949.2 0.000961 22-Aug K.NC[160.03]PHVVVGTPGR[166.11].L "sp|O00148|DX39A_HUMAN,tr|K7EPJ3|K7EPJ3_HUMAN,tr|K7EQN7|K7EQN7_HUMAN,tr|A0A0D9SEM9|A0A0D9SEM9_HUMAN" 4 1301.6538 0.33 96254 7949 2 1301.650135 651.8342 ATP-dependent RNA helicase DDX39A OS=Homo sapiens OX=9606 GN=DDX39A PE=1 SV=2 8.26 1795.8 - 326353 - - - -2.8226 - 1.587 0.419 - 99.7 1 2 0 -0.0037 12 0 0 0 1.63E+06 4.94E+06 - - - 3.3498 1 221125_WJC_METTL3_EV_vs_WT_F07.07951.07951.2 5.80E-11 17/30 R.SGGGGGGGLGSGGSIR.S sp|P35527|K1C9_HUMAN 1 1231.5905 540113.44 96255 7951 2 1231.589324 616.8025 "Keratin, type I cytoskeletal 9 OS=Homo sapiens OX=9606 GN=KRT9 PE=1 SV=3" 9.47 1796.1 - 7.91E+07 - - - -0.976 - 3.543 0.693 - 763 1 2 0 -0.0012 16 0 0 0 2.30E+10 4.26E+04 - - - 7.2691 0.9998 221125_WJC_METTL3_EV_vs_WT_F07.07955.07955.2 0.002 18-Oct R.KQEELVQQVR.K "sp|O95983|MBD3_HUMAN,tr|K7EIE8|K7EIE8_HUMAN" 2 1255.6885 1.18 96256 7955 2 1255.689288 628.8515 Methyl-CpG-binding domain protein 3 OS=Homo sapiens OX=9606 GN=MBD3 PE=1 SV=1 6.14 1796.6 - 2.28E+06 - - - 0.6674 - 2.168 0.44 - 403.6 1 2 0 0.0008 10 0 0 0 5.93E+07 5.03E+07 - - - 4.4505 0.9972 221125_WJC_METTL3_EV_vs_WT_F07.07962.07962.2 1.74 14-Sep K.RLEFENQK.T "sp|Q14683|SMC1A_HUMAN,tr|G8JLG1|G8JLG1_HUMAN,tr|A0A6Q8PHC3|A0A6Q8PHC3_HUMAN" 3 1062.5458 0.72 96261 7962 2 1062.546141 532.2802 Structural maintenance of chromosomes protein 1A OS=Homo sapiens OX=9606 GN=SMC1A PE=1 SV=2 6.14 1797.3 - 436296 - - - 0.3134 - 1.507 0.174 - 235 1 2 0 0.0003 8 0 0 0 7.45E+06 1.03E+07 - - - 1.563 0.9997 221125_WJC_METTL3_EV_vs_WT_F07.07963.07963.3 0.000507 Nov-36 R.KQEELVQQVR.K "sp|O95983|MBD3_HUMAN,tr|K7EIE8|K7EIE8_HUMAN" 2 1255.6885 1.03 96262 7963 3 1255.692244 419.5701 Methyl-CpG-binding domain protein 3 OS=Homo sapiens OX=9606 GN=MBD3 PE=1 SV=1 6.14 1797.4 - 1.58E+07 - - - 3.0215 - 2.352 0.412 - 253.8 1 2 0 0.0038 10 0 0 0 2.56E+08 2.49E+08 - - - 5.6301 0.992 221125_WJC_METTL3_EV_vs_WT_F07.07966.07966.2 0.164 20-Jun K.SQALNVTAQQK.W "sp|Q9UID6|ZN639_HUMAN,tr|J3KR59|J3KR59_HUMAN,tr|J3KR68|J3KR68_HUMAN" 3 1186.6306 0.61 96265 7966 2 1186.629619 594.3226 Zinc finger protein 639 OS=Homo sapiens OX=9606 GN=ZNF639 PE=1 SV=1 8.47 1797.8 - 124619 - - - -0.8267 - 1.364 0.131 - 97.5 1 2 0 -0.001 11 0 0 0 1.26E+06 2.07E+06 - - - 0.848 0.9999 221125_WJC_METTL3_EV_vs_WT_F07.07970.07970.3 6.68E-05 Dec-40 R.TFTEMDSHEEK[136.11].V "sp|P48444|COPD_HUMAN,tr|B0YIW6|B0YIW6_HUMAN,tr|Q6P1Q5|Q6P1Q5_HUMAN" 3 1360.5696 0.77 96267 7970 3 1360.56951 454.5305 Coatomer subunit delta OS=Homo sapiens OX=9606 GN=ARCN1 PE=1 SV=1 4.4 1798.2 - 872000 - - - -0.1 - 1.603 0.533 - 151.7 1 2 0 -0.0001 11 0 0 0 1.09E+07 1.42E+07 - - - 5.8229 0.9982 221125_WJC_METTL3_EV_vs_WT_F07.07973.07973.2 0.0117 14-Jul K.HQAVQLPR.E sp|O95758|PTBP3_HUMAN 1 947.5301 1.23 96270 7973 2 947.529167 474.7723 Polypyrimidine tract-binding protein 3 OS=Homo sapiens OX=9606 GN=PTBP3 PE=1 SV=2 9.76 1798.6 - 525077 - - - -0.9826 - 1.498 0.24 - 123.2 1 2 0 -0.0009 8 0 0 0 1.49E+07 1.21E+07 - - - 2.0322 0.9936 221125_WJC_METTL3_EV_vs_WT_F07.07976.07976.3 0.0238 Dec-48 R.RGIPPEEPGAPPR.R sp|P48634|PRC2A_HUMAN 1 1371.7259 3.1 96273 7976 3 1371.726157 458.2492 Protein PRRC2A OS=Homo sapiens OX=9606 GN=PRRC2A PE=1 SV=3 6.14 1798.9 - 335646 - - - 0.1888 - 2.024 0.146 - 193.8 1 2 0 0.0003 13 0 0 0 7.69E+06 2.48E+06 - - - 2.0794 0.9996 221125_WJC_METTL3_EV_vs_WT_F07.07978.07978.2 4.12E-06 28-Nov R.SPPGAEEPQAPPASR.D "sp|Q86VR2|RETR3_HUMAN,tr|K7EQI9|K7EQI9_HUMAN" 2 1489.7161 3 96275 7978 2 1489.72023 745.8653 Reticulophagy regulator 3 OS=Homo sapiens OX=9606 GN=RETREG3 PE=1 SV=1 4.53 1799.2 - 197995 - - - 2.7582 - 2.088 0.589 - 248.6 1 2 0 0.0041 15 0 0 0 4.59E+06 1.53E+06 - - - 5.2001 0.9998 221125_WJC_METTL3_EV_vs_WT_F07.07982.07982.2 4.50E-06 18-Oct K.NHEEEMNALR.G "sp|Q04695|K1C17_HUMAN,sp|P02533|K1C14_HUMAN,tr|K7EPJ9|K7EPJ9_HUMAN,tr|K7ESE1|K7ESE1_HUMAN,tr|F5GWP8|F5GWP8_HUMAN" 5 1241.5459 254.68 96277 7982 2 1241.54583 621.7802 "Keratin, type I cytoskeletal 17 OS=Homo sapiens OX=9606 GN=KRT17 PE=1 SV=2" 4.75 1799.7 - 1.89E+06 - - - -0.0435 - 2.104 0.413 - 414.6 1 2 0 -0.0001 10 0 0 0 4.26E+08 1.67E+06 - - - 4.1677 0.9999 221125_WJC_METTL3_EV_vs_WT_F07.07983.07983.3 0.000148 14/44 K.NC[160.03]PHVVVGTPGR.L "sp|O00148|DX39A_HUMAN,tr|K7EPJ3|K7EPJ3_HUMAN,tr|K7EQN7|K7EQN7_HUMAN,tr|A0A0D9SEM9|A0A0D9SEM9_HUMAN" 4 1291.6455 0.34 96278 7983 3 1291.647673 431.5558 ATP-dependent RNA helicase DDX39A OS=Homo sapiens OX=9606 GN=DDX39A PE=1 SV=2 8.26 1799.8 - 1.11E+06 - - - 1.6522 - 2.586 0.47 - 379.8 1 2 0 0.0021 12 0 0 0 4.24E+07 1.25E+08 - - - 6.413 0.9999 221125_WJC_METTL3_EV_vs_WT_F07.07984.07984.3 4.10E-05 Sep-36 K.NHEEEMNALR.G "sp|Q04695|K1C17_HUMAN,sp|P02533|K1C14_HUMAN,tr|K7EPJ9|K7EPJ9_HUMAN,tr|K7ESE1|K7ESE1_HUMAN,tr|F5GWP8|F5GWP8_HUMAN" 5 1241.5459 1653.76 96279 7984 3 1241.547887 414.8559 "Keratin, type I cytoskeletal 17 OS=Homo sapiens OX=9606 GN=KRT17 PE=1 SV=2" 4.75 1799.8 - 3.18E+06 - - - 1.6133 - 1.752 0.494 - 201.5 1 2 0 0.002 10 0 0 0 5.04E+08 3.05E+05 - - - 5.6847 0.9951 221125_WJC_METTL3_EV_vs_WT_F07.07985.07985.3 0.0812 Nov-48 R.VVTVSGEPEQVHK.A "sp|Q9UNW9|NOVA2_HUMAN,tr|A0A6Q8PFC2|A0A6Q8PFC2_HUMAN" 2 1407.7358 1.04 96280 7985 3 1407.736566 470.2525 RNA-binding protein Nova-2 OS=Homo sapiens OX=9606 GN=NOVA2 PE=1 SV=1 5.4 1799.9 - 726373 - - - 0.5484 - 1.692 0.205 - 112 1 2 0 0.0008 13 0 0 0 1.61E+07 1.55E+07 - - - 2.2512 0.9567 221125_WJC_METTL3_EV_vs_WT_F07.07987.07987.3 0.459 Oct-48 R.VVTVSGEPEQVHK[136.11].A "sp|Q9UNW9|NOVA2_HUMAN,tr|A0A6Q8PFC2|A0A6Q8PFC2_HUMAN" 2 1415.75 1.35 96282 7987 3 1415.750022 472.9239 RNA-binding protein Nova-2 OS=Homo sapiens OX=9606 GN=NOVA2 PE=1 SV=1 5.4 1800.2 - 602041 - - - 0.0198 - 1.58 0.104 - 49.8 1 2 0 0 13 0 0 0 1.17E+07 8.65E+06 - - - 0.9397 1 221125_WJC_METTL3_EV_vs_WT_F07.07989.07989.3 7.21E-06 Dec-40 R.TFTEMDSHEEK.V "sp|P48444|COPD_HUMAN,tr|B0YIW6|B0YIW6_HUMAN,tr|Q6P1Q5|Q6P1Q5_HUMAN" 3 1352.5554 0.78 96284 7989 3 1352.55611 451.8591 Coatomer subunit delta OS=Homo sapiens OX=9606 GN=ARCN1 PE=1 SV=1 4.4 1800.4 - 544872 - - - 0.4909 - 1.989 0.577 - 174.6 1 2 0 0.0007 11 0 0 0 1.10E+07 1.42E+07 - - - 6.9262 0.9999 221125_WJC_METTL3_EV_vs_WT_F07.07991.07991.2 4.09E-05 14/24 K.EVYQQQQYGSGGR.G "sp|Q99729|ROAA_HUMAN,tr|D6R9P3|D6R9P3_HUMAN,tr|D6RD18|D6RD18_HUMAN,tr|D6RBZ0|D6RBZ0_HUMAN" 4 1498.6801 1.31 96286 7991 2 1498.68027 750.3473 Heterogeneous nuclear ribonucleoprotein A\B OS=Homo sapiens OX=9606 GN=HNRNPAB PE=1 SV=2 6.1 1800.6 - 435325 - - - 0.1335 - 2.486 0.567 - 684.2 1 2 0 0.0002 13 0 0 0 4.84E+07 3.71E+07 - - - 5.5661 0.9999 221125_WJC_METTL3_EV_vs_WT_F07.07993.07993.2 7.50E-05 24-Dec K.EVYQQQQYGSGGR[166.11].G "sp|Q99729|ROAA_HUMAN,tr|D6R9P3|D6R9P3_HUMAN,tr|D6RD18|D6RD18_HUMAN,tr|D6RBZ0|D6RBZ0_HUMAN" 4 1508.6883 1.31 96288 7993 2 1508.687655 755.3514 Heterogeneous nuclear ribonucleoprotein A\B OS=Homo sapiens OX=9606 GN=HNRNPAB PE=1 SV=2 6.1 1800.9 - 369694 - - - -0.454 - 2.328 0.518 - 433.4 1 2 0 -0.0007 13 0 0 0 4.84E+07 3.71E+07 - - - 5.0355 1 221125_WJC_METTL3_EV_vs_WT_F07.07996.07996.2 2.87E-08 13/34 K.AGVVNGTGAPGQSPGAGR.A "sp|Q13330|MTA1_HUMAN,tr|H0Y4T7|H0Y4T7_HUMAN,tr|E7ESY4|E7ESY4_HUMAN" 3 1551.7754 1.17 96291 7996 2 1551.775119 776.895 Metastasis-associated protein MTA1 OS=Homo sapiens OX=9606 GN=MTA1 PE=1 SV=2 9.79 1801.2 - 222532 - - - -0.1598 - 2.694 0.619 - 349.4 1 2 0 -0.0002 18 0 0 0 4.04E+06 3.44E+06 - - - 6.0493 0.7843 221125_WJC_METTL3_EV_vs_WT_F07.07997.07997.2 0.000779 20-Sep G.FREVVETQEGK.T "sp|Q9NVS2|RT18A_HUMAN,tr|Q5QPA5|Q5QPA5_HUMAN" 2 1320.6674 1.49 96292 7997 2 1320.666156 661.341 "39S ribosomal protein S18a, mitochondrial OS=Homo sapiens OX=9606 GN=MRPS18A PE=1 SV=1" 4.79 1801.4 - 215831 - - - -0.9268 - 2.004 0.335 - 207.4 1 1 1 -0.0012 11 0 0 0 3.30E+06 2.22E+06 - - - 3.3955 0.999 221125_WJC_METTL3_EV_vs_WT_F07.07999.07999.3 0.00122 Oct-48 K.YDAGEHGLQEAEK.G "sp|Q93009|UBP7_HUMAN,tr|A0A669KBL1|A0A669KBL1_HUMAN,tr|F5H2X1|F5H2X1_HUMAN,tr|H3BND8|H3BND8_HUMAN" 4 1445.6423 0.95 96294 7999 3 1445.646749 482.888 Ubiquitin carboxyl-terminal hydrolase 7 OS=Homo sapiens OX=9606 GN=USP7 PE=1 SV=2 4.4 1801.6 - 211027 - - - 3.0865 - 1.739 0.393 - 67.1 1 2 0 0.0045 13 0 0 0 3.57E+06 3.77E+06 - - - 4.4205 0.9969 221125_WJC_METTL3_EV_vs_WT_F07.08005.08005.2 0.0787 16-Aug R.R[166.11]FDGVQDPR[166.11].L sp|O00264|PGRC1_HUMAN 1 1108.5528 1.47 96298 8005 2 1108.553656 555.2837 Membrane-associated progesterone receptor component 1 OS=Homo sapiens OX=9606 GN=PGRMC1 PE=1 SV=3 5.96 1802.3 - 560435 - - - 0.7307 - 1.468 0.192 - 182.1 1 2 0 0.0008 9 0 0 0 2.69E+07 1.83E+07 - - - 1.5695 0.9971 221125_WJC_METTL3_EV_vs_WT_F07.08006.08006.3 0.0349 Nov-48 K.EVYQQQQYGSGGR[166.11].G "sp|Q99729|ROAA_HUMAN,tr|D6R9P3|D6R9P3_HUMAN,tr|D6RD18|D6RD18_HUMAN,tr|D6RBZ0|D6RBZ0_HUMAN" 4 1508.6883 0.98 96299 8006 3 1508.694846 503.9034 Heterogeneous nuclear ribonucleoprotein A\B OS=Homo sapiens OX=9606 GN=HNRNPAB PE=1 SV=2 6.1 1802.5 - 529160 - - - 4.3124 - 1.98 0.346 - 126.9 1 2 0 0.0065 13 0 0 0 5.75E+06 5.85E+06 - - - 4.2478 1 221125_WJC_METTL3_EV_vs_WT_F07.08009.08009.2 6.56E-10 14/34 K.AGVVNGTGAPGQSPGAGR[166.11].A "sp|Q13330|MTA1_HUMAN,tr|H0Y4T7|H0Y4T7_HUMAN,tr|E7ESY4|E7ESY4_HUMAN" 3 1561.7836 1.17 96302 8009 2 1561.784417 781.8991 Metastasis-associated protein MTA1 OS=Homo sapiens OX=9606 GN=MTA1 PE=1 SV=2 9.79 1802.9 - 441892 - - - 0.4994 - 2.815 0.673 - 372.7 1 2 0 0.0008 18 0 0 0 4.04E+06 3.44E+06 - - - 6.556 0.9915 221125_WJC_METTL3_EV_vs_WT_F07.08016.08016.3 0.164 Sep-60 K.ELHNTPYGTASEPSEK.A sp|Q9NXV2|KCTD5_HUMAN 1 1758.8061 6.05 96309 8016 3 1758.806566 587.276 BTB\POZ domain-containing protein KCTD5 OS=Homo sapiens OX=9606 GN=KCTD5 PE=1 SV=1 4.75 1803.8 - 188842 - - - 0.2888 - 1.199 0.26 - 25.5 1 2 0 0.0005 16 0 0 0 1.81E+06 2.99E+05 - - - 1.9043 0.9976 221125_WJC_METTL3_EV_vs_WT_F07.08017.08017.2 0.0403 22-Aug K.AQGPLPNQHSLK.G sp|Q4VCS5|AMOT_HUMAN 1 1288.6888 14.39 96310 8017 2 1288.689922 645.3517 Angiomotin OS=Homo sapiens OX=9606 GN=AMOT PE=1 SV=1 8.8 1803.9 - 103575 - - - 0.8831 - 1.347 0.272 - 155.4 1 2 0 0.0011 12 0 0 0 1.94E+06 1.35E+05 - - - 1.8334 0.9996 221125_WJC_METTL3_EV_vs_WT_F07.08021.08021.2 0.000101 22-Oct R.ELTNQQEASVER.Q "sp|Q14203|DCTN1_HUMAN,tr|A0A804CDA6|A0A804CDA6_HUMAN,tr|E7EX90|E7EX90_HUMAN,tr|A0A7P0Z4C3|A0A7P0Z4C3_HUMAN,tr|Q6AWB1|Q6AWB1_HUMAN" 5 1402.6688 3.47 96313 8021 2 1402.672631 702.3417 Dynactin subunit 1 OS=Homo sapiens OX=9606 GN=DCTN1 PE=1 SV=3 4.25 1804.4 - 180993 - - - 2.7056 - 2.419 0.496 - 452.5 1 2 0 0.0038 12 0 0 0 1.56E+06 4.51E+05 - - - 5.0275 0.988 221125_WJC_METTL3_EV_vs_WT_F07.08022.08022.2 0.0212 18-Jun K.HLPDNEC[160.03]IEK[136.11].V sp|P54136|SYRC_HUMAN 1 1261.5852 2.94 96314 8022 2 1261.588817 631.7999 "Arginine--tRNA ligase, cytoplasmic OS=Homo sapiens OX=9606 GN=RARS1 PE=1 SV=2" 4.65 1804.5 - 184315 - - - 2.8377 - 1.13 0.285 - 98.3 1 2 0 0.0036 10 0 0 0 1.96E+07 6.66E+06 - - - 1.486 0.9999 221125_WJC_METTL3_EV_vs_WT_F07.08032.08032.2 0.000283 18-Dec K.STTTGHLIYK[136.11].C "sp|Q05639|EF1A2_HUMAN,sp|P68104|EF1A1_HUMAN,sp|Q5VTE0|EF1A3_HUMAN,tr|A0A2R8Y488|A0A2R8Y488_HUMAN,tr|A0A2R8YDN5|A0A2R8YDN5_HUMAN,tr|A0A7I2V659|A0A7I2V659_HUMAN,tr|A0A7I2V3H3|A0A7I2V3H3_HUMAN,tr|Q5JR01|Q5JR01_HUMAN,tr|A0A2U3TZH3|A0A2U3TZH3_HUMAN,tr|A0A7I2V5N4|A0A7I2V5N4_HUMAN,tr|A0A087WVQ9|A0A087WVQ9_HUMAN,tr|A6PW80|A6PW80_HUMAN,tr|A0A087WV01|A0A087WV01_HUMAN,tr|A0A2R8Y660|A0A2R8Y660_HUMAN,tr|A0A6Q8PFK6|A0A6Q8PFK6_HUMAN" 15 1127.6066 0.42 96324 8032 2 1127.606245 564.8106 Elongation factor 1-alpha 2 OS=Homo sapiens OX=9606 GN=EEF1A2 PE=1 SV=1 8.33 1805.3 - 790938 - - - -0.3361 - 2.456 0.454 - 807.7 1 2 0 -0.0004 10 0 0 0 8.86E+06 2.09E+07 - - - 4.9022 0.9859 221125_WJC_METTL3_EV_vs_WT_F07.08033.08033.2 0.11 18-Sep K.SVEDRFDQQK.N sp|P15924|DESP_HUMAN 1 1250.5891 999 96325 8033 2 1250.588865 626.3018 Desmoplakin OS=Homo sapiens OX=9606 GN=DSP PE=1 SV=3 4.56 1805.5 - 704159 - - - -0.2111 - 1.604 0.243 - 219.6 1 2 1 -0.0003 10 0 0 0 4.01E+06 0.00E+00 - - - 2.1546 1 221125_WJC_METTL3_EV_vs_WT_F07.08034.08034.2 0.000274 13/26 K.SAVEAQNEVTENPK[136.11].Q sp|Q32MZ4|LRRF1_HUMAN 1 1522.7355 0.9 96326 8034 2 1522.737845 762.375 Leucine-rich repeat flightless-interacting protein 1 OS=Homo sapiens OX=9606 GN=LRRFIP1 PE=1 SV=2 4.25 1805.6 - 567749 - - - 1.5623 - 3.021 0.573 - 788.1 1 2 0 0.0024 14 0 0 0 5.08E+06 5.64E+06 - - - 6.0468 1 221125_WJC_METTL3_EV_vs_WT_F07.08036.08036.2 6.64E-07 14/26 K.SAVEAQNEVTENPK.Q sp|Q32MZ4|LRRF1_HUMAN 1 1514.7213 0.7 96328 8036 2 1514.724203 758.3679 Leucine-rich repeat flightless-interacting protein 1 OS=Homo sapiens OX=9606 GN=LRRFIP1 PE=1 SV=2 4.25 1805.8 - 355065 - - - 1.939 - 2.97 0.599 - 1007.4 1 2 0 0.0029 14 0 0 0 3.92E+06 5.64E+06 - - - 6.196 0.9997 221125_WJC_METTL3_EV_vs_WT_F07.08043.08043.3 0.00497 Oct-40 R.KTNPEIQSTLR.K sp|P31944|CASPE_HUMAN 1 1285.699 63.22 96333 8043 3 1285.699124 429.5736 Caspase-14 OS=Homo sapiens OX=9606 GN=CASP14 PE=1 SV=2 8.75 1806.5 - 2.92E+06 - - - 0.0856 - 2.29 0.296 - 225.6 1 2 0 0.0001 11 0 0 0 9.56E+07 1.51E+06 - - - 4.1939 1 221125_WJC_METTL3_EV_vs_WT_F07.08044.08044.3 1.97E-06 Dec-36 R.SC[160.03]YDLSC[160.03]HAR.A "sp|P41250|GARS_HUMAN,tr|H7C443|H7C443_HUMAN,tr|A0A6Q8PGI6|A0A6Q8PGI6_HUMAN,tr|A0A6Q8PGA8|A0A6Q8PGA8_HUMAN,tr|A0A6Q8PGW4|A0A6Q8PGW4_HUMAN,tr|A0A6Q8PGZ8|A0A6Q8PGZ8_HUMAN,tr|A0A6Q8PHH9|A0A6Q8PHH9_HUMAN,tr|A0A6Q8PHI7|A0A6Q8PHI7_HUMAN,tr|A0A6Q8PFZ6|A0A6Q8PFZ6_HUMAN" 9 1267.5074 0.4 96334 8044 3 1267.507001 423.5097 Glycine--tRNA ligase OS=Homo sapiens OX=9606 GN=GARS1 PE=1 SV=3 6.45 1806.6 - 2.74E+06 - - - -0.3077 - 2.66 0.609 - 280 1 2 0 -0.0004 10 0 0 0 2.29E+07 5.72E+07 - - - 8.1868 0.9981 221125_WJC_METTL3_EV_vs_WT_F07.08046.08046.2 0.00418 16-Sep K.K[136.11]YEPPVPTR[166.11].V sp|P62191|PRS4_HUMAN 1 1103.6094 0.61 96336 8046 2 1103.612376 552.812 26S proteasome regulatory subunit 4 OS=Homo sapiens OX=9606 GN=PSMC1 PE=1 SV=1 8.59 1806.7 - 784865 - - - 2.683 - 1.98 0.266 - 356.2 1 2 0 0.003 9 0 0 0 3.78E+06 6.22E+06 - - - 2.981 0.9999 221125_WJC_METTL3_EV_vs_WT_F07.08048.08048.2 2.12E-06 20-Dec R.SGELAQEYDK[136.11]R[166.11].K "sp|Q14683|SMC1A_HUMAN,tr|G8JLG1|G8JLG1_HUMAN" 2 1312.6378 1 96338 8048 2 1312.63757 657.3262 Structural maintenance of chromosomes protein 1A OS=Homo sapiens OX=9606 GN=SMC1A PE=1 SV=2 4.68 1807 - 687204 - - - -0.1859 - 2.627 0.529 - 722 1 2 0 -0.0002 11 0 0 0 7.41E+06 7.44E+06 - - - 5.5609 0.9998 221125_WJC_METTL3_EV_vs_WT_F07.08049.08049.2 1.56E-05 20-Dec R.KTNPEIQSTLR.K sp|P31944|CASPE_HUMAN 1 1285.699 999 96339 8049 2 1285.70081 643.8568 Caspase-14 OS=Homo sapiens OX=9606 GN=CASP14 PE=1 SV=2 8.75 1807.1 - 482940 - - - 1.3969 - 2.427 0.516 - 558.2 1 2 0 0.0018 11 0 0 0 1.90E+07 0.00E+00 - - - 5.2502 0.9997 221125_WJC_METTL3_EV_vs_WT_F07.08050.08050.2 9.59E-06 16-Sep K.DYGNSPLHR[166.11].F "sp|P26599|PTBP1_HUMAN,tr|A0A0U1RRM4|A0A0U1RRM4_HUMAN,tr|A6NLN1|A6NLN1_HUMAN,tr|K7ELW5|K7ELW5_HUMAN,tr|A0A0D9SF20|A0A0D9SF20_HUMAN,tr|A0A7I2V621|A0A7I2V621_HUMAN,tr|A0A087WUW5|A0A087WUW5_HUMAN" 7 1067.5024 1.16 96340 8050 2 1067.504003 534.7585 Polypyrimidine tract-binding protein 1 OS=Homo sapiens OX=9606 GN=PTBP1 PE=1 SV=1 6.74 1807.3 - 464267 - - - 1.5232 - 1.841 0.488 - 321 1 2 0 0.0016 9 0 0 0 4.52E+07 3.91E+07 - - - 4.4105 0.9931 221125_WJC_METTL3_EV_vs_WT_F07.08053.08053.3 0.0507 Aug-44 R.C[160.03]GNNPLIGR[166.11]PNK[136.11].V sp|O60306|AQR_HUMAN 1 1356.7051 4.12 96343 8053 3 1356.705489 453.2423 RNA helicase aquarius OS=Homo sapiens OX=9606 GN=AQR PE=1 SV=4 9.51 1807.6 - 443038 - - - 0.2698 - 1.422 0.238 - 52 2 2 0 0.0004 12 0 0 0 1.55E+07 3.76E+06 - - - 2.0299 1 221125_WJC_METTL3_EV_vs_WT_F07.08056.08056.2 0.00434 13/20 R.SAEELK[136.11]EMQDK[136.11].V "sp|O95347|SMC2_HUMAN,tr|Q5T821|Q5T821_HUMAN" 2 1322.6359 0.81 96346 8056 2 1322.632709 662.3252 Structural maintenance of chromosomes protein 2 OS=Homo sapiens OX=9606 GN=SMC2 PE=1 SV=2 4.41 1808 - 244960 - - - -2.399 - 2.847 0.537 - 686.4 1 2 1 -0.0032 11 0 0 0 1.07E+06 1.32E+06 - - - 5.8367 1 221125_WJC_METTL3_EV_vs_WT_F07.08061.08061.3 8.68E-05 14/48 K.LMELHGEGSSSGK.A "sp|P61247|RS3A_HUMAN,tr|D6R9B6|D6R9B6_HUMAN,tr|H0Y9Y4|H0Y9Y4_HUMAN,tr|D6RAT0|D6RAT0_HUMAN,tr|D6RG13|D6RG13_HUMAN" 5 1330.6187 0.92 96349 8061 3 1330.617673 444.5468 40S ribosomal protein S3a OS=Homo sapiens OX=9606 GN=RPS3A PE=1 SV=2 5.4 1808.6 - 4.25E+06 - - - -0.7831 - 2.488 0.475 - 273.1 1 2 0 -0.001 13 0 0 0 2.38E+08 2.60E+08 - - - 6.3068 0.9977 221125_WJC_METTL3_EV_vs_WT_F07.08065.08065.3 0.00306 13/48 K.ETGYVVERPSTTK.D "sp|Q9NYF8|BCLF1_HUMAN,tr|E9PKI6|E9PKI6_HUMAN,tr|A0A1W2PQ43|A0A1W2PQ43_HUMAN,tr|E9PK91|E9PK91_HUMAN,tr|E9PK09|E9PK09_HUMAN,tr|E9PQN2|E9PQN2_HUMAN" 6 1465.7413 2.17 96353 8065 3 1465.739643 489.5877 Bcl-2-associated transcription factor 1 OS=Homo sapiens OX=9606 GN=BCLAF1 PE=1 SV=2 6.24 1808.8 - 1.73E+06 - - - -1.1121 - 2.087 0.201 - 184.2 1 2 0 -0.0016 13 0 0 0 8.05E+09 3.71E+09 - - - 2.7753 0.9999 221125_WJC_METTL3_EV_vs_WT_F07.08066.08066.3 5.25E-05 Dec-40 R.HQGVMVGMGQK[136.11].D "sp|P63261|ACTG_HUMAN,sp|P68133|ACTS_HUMAN,sp|P62736|ACTA_HUMAN,sp|P68032|ACTC_HUMAN,sp|Q562R1|ACTBL_HUMAN,sp|P60709|ACTB_HUMAN,sp|P63267|ACTH_HUMAN,tr|I3L3I0|I3L3I0_HUMAN,tr|G5E9R0|G5E9R0_HUMAN,tr|E7EVS6|E7EVS6_HUMAN,tr|B8ZZJ2|B8ZZJ2_HUMAN,tr|J3KT65|J3KT65_HUMAN,tr|I3L3R2|I3L3R2_HUMAN,tr|K7EM38|K7EM38_HUMAN,tr|F6QUT6|F6QUT6_HUMAN,tr|C9JTX5|C9JTX5_HUMAN,tr|A0A6Q8PH58|A0A6Q8PH58_HUMAN,tr|F6UVQ4|F6UVQ4_HUMAN,tr|F8WB63|F8WB63_HUMAN,tr|I3L1U9|I3L1U9_HUMAN,tr|A0A2R8Y793|A0A2R8Y793_HUMAN,tr|I3L4N8|I3L4N8_HUMAN,tr|C9JUM1|C9JUM1_HUMAN,tr|C9JZR7|C9JZR7_HUMAN,tr|C9JFL5|C9JFL5_HUMAN,tr|A0A2R8YGF8|A0A2R8YGF8_HUMAN,tr|A6NL76|A6NL76_HUMAN" 27 1178.578 1.03 96354 8066 3 1178.577696 393.8666 "Actin, cytoplasmic 2 OS=Homo sapiens OX=9606 GN=ACTG1 PE=1 SV=1" 8.76 1808.9 - 1.54E+06 - - - -0.2435 - 2.296 0.423 - 300.7 1 2 0 -0.0003 11 0 0 0 5.16E+07 4.99E+07 - - - 5.6172 0.9999 221125_WJC_METTL3_EV_vs_WT_F07.08068.08068.2 0.00912 18-Nov K.STTTGHLIYK.C "sp|Q05639|EF1A2_HUMAN,sp|P68104|EF1A1_HUMAN,sp|Q5VTE0|EF1A3_HUMAN,tr|A0A2R8Y488|A0A2R8Y488_HUMAN,tr|A0A2R8YDN5|A0A2R8YDN5_HUMAN,tr|A0A7I2V659|A0A7I2V659_HUMAN,tr|A0A7I2V3H3|A0A7I2V3H3_HUMAN,tr|Q5JR01|Q5JR01_HUMAN,tr|A0A2U3TZH3|A0A2U3TZH3_HUMAN,tr|A0A7I2V5N4|A0A7I2V5N4_HUMAN,tr|A0A087WVQ9|A0A087WVQ9_HUMAN,tr|A6PW80|A6PW80_HUMAN,tr|A0A087WV01|A0A087WV01_HUMAN,tr|A0A2R8Y660|A0A2R8Y660_HUMAN,tr|A0A6Q8PFK6|A0A6Q8PFK6_HUMAN" 15 1119.5924 0.42 96356 8068 2 1119.591816 560.8035 Elongation factor 1-alpha 2 OS=Homo sapiens OX=9606 GN=EEF1A2 PE=1 SV=1 8.33 1809.1 - 1.22E+06 - - - -0.5431 - 2.389 0.417 - 624.5 1 2 0 -0.0006 10 0 0 0 8.86E+06 2.09E+07 - - - 4.5516 0.9998 221125_WJC_METTL3_EV_vs_WT_F07.08069.08069.3 0.000534 14/48 R.ALLQQQPEDDSK[136.11]R[166.11].S sp|Q9UHB9|SRP68_HUMAN 1 1544.7914 1.02 96357 8069 3 1544.791124 515.9377 Signal recognition particle subunit SRP68 OS=Homo sapiens OX=9606 GN=SRP68 PE=1 SV=2 4.56 1809.2 - 1.01E+06 - - - -0.1495 - 2.098 0.363 - 133.7 1 2 0 -0.0002 13 0 0 0 1.00E+07 9.78E+06 - - - 4.5961 0.7904 221125_WJC_METTL3_EV_vs_WT_F07.08070.08070.2 0.435 16-Aug F.SSQR[166.11]PVVDR[166.11].Q "sp|Q5JSZ5|PRC2B_HUMAN,tr|A0A804HKC3|A0A804HKC3_HUMAN,tr|A0A804HJR4|A0A804HJR4_HUMAN" 3 1062.5685 1.95 96358 8070 2 1062.567618 532.2915 Protein PRRC2B OS=Homo sapiens OX=9606 GN=PRRC2B PE=1 SV=2 9.31 1809.3 - 444121 - - - -0.8263 - 1.359 0.201 - 138.6 2 1 0 -0.0009 9 0 0 0 5.53E+06 2.83E+06 - - - 1.2783 0.9998 221125_WJC_METTL3_EV_vs_WT_F07.08071.08071.2 2.81E-05 18-Sep R.SC[160.03]YDLSC[160.03]HAR.A "sp|P41250|GARS_HUMAN,tr|H7C443|H7C443_HUMAN,tr|A0A6Q8PGI6|A0A6Q8PGI6_HUMAN,tr|A0A6Q8PGA8|A0A6Q8PGA8_HUMAN,tr|A0A6Q8PGW4|A0A6Q8PGW4_HUMAN,tr|A0A6Q8PGZ8|A0A6Q8PGZ8_HUMAN,tr|A0A6Q8PHH9|A0A6Q8PHH9_HUMAN,tr|A0A6Q8PHI7|A0A6Q8PHI7_HUMAN,tr|A0A6Q8PFZ6|A0A6Q8PFZ6_HUMAN" 9 1267.5074 2.04 96359 8071 2 1267.509137 634.761 Glycine--tRNA ligase OS=Homo sapiens OX=9606 GN=GARS1 PE=1 SV=3 6.45 1809.5 - 279762 - - - 1.3775 - 1.815 0.546 - 376 1 2 0 0.0017 10 0 0 0 2.29E+06 1.12E+06 - - - 4.7371 0.9947 221125_WJC_METTL3_EV_vs_WT_F07.08072.08072.2 0.202 24-Jun K.LQGGTPQEPPNPR.M "sp|Q9H0B6|KLC2_HUMAN,tr|A8MZ87|A8MZ87_HUMAN" 2 1389.7001 7.13 96360 8072 2 1389.700938 695.8573 Kinesin light chain 2 OS=Homo sapiens OX=9606 GN=KLC2 PE=1 SV=1 6 1809.6 - 256214 - - - 0.6196 - 1.363 0.178 - 92.6 1 2 0 0.0009 13 0 0 0 1.64E+06 2.29E+05 - - - 1.1503 1 221125_WJC_METTL3_EV_vs_WT_F07.08073.08073.2 1.26E-07 14/24 K.LMELHGEGSSSGK.A "sp|P61247|RS3A_HUMAN,tr|D6R9B6|D6R9B6_HUMAN,tr|H0Y9Y4|H0Y9Y4_HUMAN,tr|D6RAT0|D6RAT0_HUMAN,tr|D6RG13|D6RG13_HUMAN" 5 1330.6187 0.88 96361 8073 2 1330.613629 666.3166 40S ribosomal protein S3a OS=Homo sapiens OX=9606 GN=RPS3A PE=1 SV=2 5.4 1809.7 - 253606 - - - -3.8223 - 2.798 0.641 - 794.3 1 2 0 -0.0051 13 0 0 0 2.38E+07 2.69E+07 - - - 6.4145 0.9881 221125_WJC_METTL3_EV_vs_WT_F07.08077.08077.2 1.58 16-Jun R.RFDGVQDPR.L sp|O00264|PGRC1_HUMAN 1 1088.5363 0.9 96364 8077 2 1088.535434 545.2754 Membrane-associated progesterone receptor component 1 OS=Homo sapiens OX=9606 GN=PGRMC1 PE=1 SV=3 5.96 1810.2 - 2.03E+06 - - - -0.8011 - 1.187 0.14 - 113.9 1 2 0 -0.0009 9 0 0 0 2.45E+07 2.73E+07 - - - 0.5707 1 221125_WJC_METTL3_EV_vs_WT_F07.08079.08079.3 1.16E-06 14/48 K.LMELHGEGSSSGK[136.11].A "sp|P61247|RS3A_HUMAN,tr|D6R9B6|D6R9B6_HUMAN,tr|H0Y9Y4|H0Y9Y4_HUMAN,tr|D6RAT0|D6RAT0_HUMAN,tr|D6RG13|D6RG13_HUMAN" 5 1338.6329 0.92 96365 8079 3 1338.632131 447.2182 40S ribosomal protein S3a OS=Homo sapiens OX=9606 GN=RPS3A PE=1 SV=2 5.4 1810.5 - 1.41E+07 - - - -0.5857 - 2.674 0.529 - 266.8 1 2 0 -0.0008 13 0 0 0 2.39E+08 2.61E+08 - - - 7.1044 0.9991 221125_WJC_METTL3_EV_vs_WT_F07.08080.08080.3 0.00403 Oct-56 R.MFGGPGTASRPSSSR.S "sp|P08670|VIME_HUMAN,tr|B0YJC4|B0YJC4_HUMAN,tr|A0A1B0GVG8|A0A1B0GVG8_HUMAN,tr|A0A1B0GTT5|A0A1B0GTT5_HUMAN" 4 1493.7045 1.7 96366 8080 3 1493.703501 498.9088 Vimentin OS=Homo sapiens OX=9606 GN=VIM PE=1 SV=4 12 1810.5 - 3.03E+06 - - - -0.6755 - 1.903 0.282 - 107.6 1 2 0 -0.001 15 0 0 0 2.87E+09 1.69E+09 - - - 3.3627 0.9991 221125_WJC_METTL3_EV_vs_WT_F07.08081.08081.3 3.74E-05 Dec-56 R.MFGGPGTASR[166.11]PSSSR[166.11].S "sp|P08670|VIME_HUMAN,tr|B0YJC4|B0YJC4_HUMAN,tr|A0A1B0GVG8|A0A1B0GVG8_HUMAN,tr|A0A1B0GTT5|A0A1B0GTT5_HUMAN" 4 1513.7211 1.7 96367 8081 3 1513.720004 505.581 Vimentin OS=Homo sapiens OX=9606 GN=VIM PE=1 SV=4 12 1810.6 - 2.03E+06 - - - -0.691 - 2.028 0.272 - 151.2 1 2 0 -0.001 15 0 0 0 2.87E+09 1.69E+09 - - - 3.4172 0.9998 221125_WJC_METTL3_EV_vs_WT_F07.08082.08082.3 0.00148 Nov-44 K.IGEEEIQKPEEK.V sp|Q15459|SF3A1_HUMAN 1 1427.7144 1.58 96368 8082 3 1427.714846 476.9121 Splicing factor 3A subunit 1 OS=Homo sapiens OX=9606 GN=SF3A1 PE=1 SV=1 4.33 1810.6 - 1.98E+06 - - - 0.3194 - 2.032 0.375 - 173 1 2 0 0.0005 12 0 0 0 1.36E+08 8.62E+07 - - - 4.6861 1 221125_WJC_METTL3_EV_vs_WT_F07.08083.08083.3 1.19E-05 15/48 K.ETGYVVER[166.11]PSTTK[136.11].D "sp|Q9NYF8|BCLF1_HUMAN,tr|E9PKI6|E9PKI6_HUMAN,tr|A0A1W2PQ43|A0A1W2PQ43_HUMAN,tr|E9PK91|E9PK91_HUMAN,tr|E9PK09|E9PK09_HUMAN,tr|E9PQN2|E9PQN2_HUMAN" 6 1483.7637 2.17 96369 8083 3 1483.765497 495.5952 Bcl-2-associated transcription factor 1 OS=Homo sapiens OX=9606 GN=BCLAF1 PE=1 SV=2 6.24 1810.7 - 1.36E+06 - - - 1.1821 - 2.656 0.475 - 220.8 1 2 0 0.0018 13 0 0 0 8.04E+09 3.71E+09 - - - 6.4837 0.9925 221125_WJC_METTL3_EV_vs_WT_F07.08084.08084.2 6.81E-05 24-Dec S.VTSSTISSNVASK.A sp|P35908|K22E_HUMAN 1 1279.662 11.21 96370 8084 2 1279.661626 640.8383 "Keratin, type II cytoskeletal 2 epidermal OS=Homo sapiens OX=9606 GN=KRT2 PE=1 SV=2" 8.72 1810.8 - 1.31E+06 - - - -0.261 - 2.322 0.485 - 489.1 1 1 0 -0.0003 13 0 0 0 3.16E+07 2.82E+06 - - - 4.7852 0.9999 221125_WJC_METTL3_EV_vs_WT_F07.08085.08085.3 0.00633 15/48 R.ALLQQQPEDDSKR.S sp|Q9UHB9|SRP68_HUMAN 1 1526.7689 1.02 96371 8085 3 1526.767376 509.9302 Signal recognition particle subunit SRP68 OS=Homo sapiens OX=9606 GN=SRP68 PE=1 SV=2 4.56 1810.9 - 1.08E+06 - - - -0.9884 - 2.512 0.348 - 348.6 1 2 0 -0.0015 13 0 0 0 1.00E+07 9.78E+06 - - - 4.9168 1 221125_WJC_METTL3_EV_vs_WT_F07.08087.08087.2 1.43E-05 18/30 R.QAEQLSAAGEGGDAGR[166.11].M "sp|Q9NRX1|PNO1_HUMAN,tr|F8WBJ6|F8WBJ6_HUMAN" 2 1525.6996 0.92 96373 8087 2 1525.696779 763.8571 RNA-binding protein PNO1 OS=Homo sapiens OX=9606 GN=PNO1 PE=1 SV=1 4.14 1811.2 - 914279 - - - -1.8706 - 3.368 0.624 - 1137.4 1 2 0 -0.0029 16 0 0 0 2.53E+07 2.77E+07 - - - 6.6344 0.9991 221125_WJC_METTL3_EV_vs_WT_F07.08088.08088.3 0.0171 Jul-36 R.SWGNNYPQHR.Q "sp|Q9BTL3|RAMAC_HUMAN,tr|A0A3B3IU46|A0A3B3IU46_HUMAN" 2 1257.5639 1.1 96374 8088 3 1257.562452 420.1952 RNA guanine-N7 methyltransferase activating subunit OS=Homo sapiens OX=9606 GN=RAMAC PE=1 SV=1 8.49 1811.2 - 886712 - - - -1.1657 - 1.592 0.319 - 74.2 1 2 0 -0.0015 10 0 0 0 8.24E+06 7.52E+06 - - - 3.4541 0.9987 221125_WJC_METTL3_EV_vs_WT_F07.08089.08089.3 0.000843 Nov-44 K.LDPHNHVLYSNR[166.11].S "sp|P31948|STIP1_HUMAN,tr|F5GXD8|F5GXD8_HUMAN,tr|F5H783|F5H783_HUMAN" 3 1473.7352 115.29 96375 8089 3 1473.734272 492.2524 Stress-induced-phosphoprotein 1 OS=Homo sapiens OX=9606 GN=STIP1 PE=1 SV=1 6.92 1811.3 - 863903 - - - -0.65 - 2.041 0.233 - 166.1 1 2 0 -0.001 12 0 0 0 5.55E+09 4.82E+07 - - - 3.115 0.9998 221125_WJC_METTL3_EV_vs_WT_F07.08090.08090.2 2.98 20-Nov R.SGELAQEYDKR.K "sp|Q14683|SMC1A_HUMAN,tr|G8JLG1|G8JLG1_HUMAN" 2 1294.6153 1 96376 8090 2 1294.614231 648.3149 Structural maintenance of chromosomes protein 1A OS=Homo sapiens OX=9606 GN=SMC1A PE=1 SV=2 4.68 1811.5 - 861899 - - - -0.8597 - 2.625 0.391 - 590.4 1 2 0 -0.0011 11 0 0 0 7.41E+06 7.44E+06 - - - 4.5393 1 221125_WJC_METTL3_EV_vs_WT_F07.08091.08091.2 2.20E-08 16/30 R.QAEQLSAAGEGGDAGR.M "sp|Q9NRX1|PNO1_HUMAN,tr|F8WBJ6|F8WBJ6_HUMAN" 2 1515.6914 0.92 96377 8091 2 1515.685065 758.853 RNA-binding protein PNO1 OS=Homo sapiens OX=9606 GN=PNO1 PE=1 SV=1 4.14 1811.6 - 767062 - - - -4.1552 - 3.486 0.622 - 735.4 1 2 0 -0.0063 16 0 0 0 2.53E+07 2.77E+07 - - - 6.7032 0.9999 221125_WJC_METTL3_EV_vs_WT_F07.08092.08092.2 2.23E-06 13/20 R.K[136.11]LDSDVYPSSK[136.11].Q "sp|Q2KHR3|QSER1_HUMAN,tr|A0A3B3IRW6|A0A3B3IRW6_HUMAN" 2 1253.6474 3.75 96378 8092 2 1253.647795 627.831 Glutamine and serine-rich protein 1 OS=Homo sapiens OX=9606 GN=QSER1 PE=1 SV=3 5.96 1811.7 - 440840 - - - 0.2888 - 2.238 0.502 - 363.7 1 2 0 0.0004 11 0 0 0 9.04E+06 2.41E+06 - - - 4.9279 1 221125_WJC_METTL3_EV_vs_WT_F07.08093.08093.2 2.80E-09 14/22 L.MELHGEGSSSGK.A "sp|P61247|RS3A_HUMAN,tr|D6R9B6|D6R9B6_HUMAN,tr|H0Y9Y4|H0Y9Y4_HUMAN,tr|D6RAT0|D6RAT0_HUMAN,tr|D6RG13|D6RG13_HUMAN" 5 1217.5347 1.02 96379 8093 2 1217.536192 609.7746 40S ribosomal protein S3a OS=Homo sapiens OX=9606 GN=RPS3A PE=1 SV=2 5.38 1811.9 - 418126 - - - 1.2657 - 2.456 0.622 - 765.1 1 1 0 0.0015 12 0 0 0 6.83E+06 6.73E+06 - - - 5.9988 1 221125_WJC_METTL3_EV_vs_WT_F07.08094.08094.2 5.26E-06 23/38 S.AAPGSAAPAAGSAPAAAEEK.K "sp|P05387|RLA2_HUMAN,tr|H0YDD8|H0YDD8_HUMAN" 2 1693.8271 2.89 96380 8094 2 1693.829179 847.9208 60S acidic ribosomal protein P2 OS=Homo sapiens OX=9606 GN=RPLP2 PE=1 SV=1 4.53 1812 - 323514 - - - 1.2109 - 3.626 0.655 - 1269.4 1 1 0 0.0021 20 0 0 0 1.38E+07 4.76E+06 - - - 7.0451 0.9999 221125_WJC_METTL3_EV_vs_WT_F07.08095.08095.2 8.18E-06 30-Oct R.SPQPVC[160.03]SPAGSEGTPK.G "sp|Q6KC79|NIPBL_HUMAN,tr|A0A590UJS4|A0A590UJS4_HUMAN" 2 1597.7406 3.21 96381 8095 2 1597.739653 799.8776 Nipped-B-like protein OS=Homo sapiens OX=9606 GN=NIPBL PE=1 SV=2 5.72 1812.1 - 319058 - - - -0.6059 - 2.174 0.614 - 213.7 1 2 0 -0.001 16 0 0 0 1.59E+07 4.94E+06 - - - 5.4849 0.9899 221125_WJC_METTL3_EV_vs_WT_F07.08096.08096.2 0.0432 22-Sep R.GKGEITPAAIQK.M "sp|Q15532|SSXT_HUMAN,tr|X6R3J2|X6R3J2_HUMAN,tr|J3QS72|J3QS72_HUMAN,tr|J3QQM2|J3QQM2_HUMAN,tr|J3KT74|J3KT74_HUMAN,tr|J3QQW2|J3QQW2_HUMAN,tr|F5GWN1|F5GWN1_HUMAN,tr|J3KRP6|J3KRP6_HUMAN" 8 1211.6874 1.68 96382 8096 2 1211.68788 606.851 Protein SSXT OS=Homo sapiens OX=9606 GN=SS18 PE=1 SV=3 8.59 1812.3 - 242638 - - - 0.4069 - 1.587 0.305 - 138.2 1 2 1 0.0005 12 0 0 0 2.54E+06 1.51E+06 - - - 2.5088 0.9999 221125_WJC_METTL3_EV_vs_WT_F07.08100.08100.2 7.94E-05 13/24 K.ETGYVVERPSTTK.D "sp|Q9NYF8|BCLF1_HUMAN,tr|E9PKI6|E9PKI6_HUMAN,tr|A0A1W2PQ43|A0A1W2PQ43_HUMAN,tr|E9PK91|E9PK91_HUMAN,tr|E9PK09|E9PK09_HUMAN,tr|E9PQN2|E9PQN2_HUMAN" 6 1465.7413 2.19 96385 8100 2 1465.741684 733.8779 Bcl-2-associated transcription factor 1 OS=Homo sapiens OX=9606 GN=BCLAF1 PE=1 SV=2 6.24 1812.7 - 492025 - - - 0.2804 - 2.465 0.496 - 600.8 1 2 0 0.0004 13 0 0 0 8.45E+08 3.86E+08 - - - 5.0198 1 221125_WJC_METTL3_EV_vs_WT_F07.08103.08103.3 0.000253 16/44 R.AAPGAEFAPNK[136.11]R[166.11].R "sp|Q15233|NONO_HUMAN,tr|A0A7I2V535|A0A7I2V535_HUMAN,tr|A0A7I2V4K9|A0A7I2V4K9_HUMAN,tr|A0A7I2V4J2|A0A7I2V4J2_HUMAN,tr|A0A7I2V5Y7|A0A7I2V5Y7_HUMAN" 5 1245.6585 11.54 96387 8103 3 1245.656614 416.2268 Non-POU domain-containing octamer-binding protein OS=Homo sapiens OX=9606 GN=NONO PE=1 SV=4 8.79 1813 - 7.89E+06 - - - -1.506 - 2.748 0.562 - 437.1 1 2 0 -0.0019 12 0 0 0 2.15E+09 1.86E+08 - - - 7.6072 0.9996 221125_WJC_METTL3_EV_vs_WT_F07.08105.08105.2 0.00167 16-Sep K.QDSGHLDLR[166.11].N "sp|Q86U44|MTA70_HUMAN,tr|B4E349|B4E349_HUMAN,tr|F5H6D8|F5H6D8_HUMAN,tr|B4DTN4|B4DTN4_HUMAN" 4 1049.5129 0 96389 8105 2 1049.512625 525.7637 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 5.21 1813.1 - 1.95E+06 - - - -0.3011 - 1.671 0.385 - 251.6 1 2 0 -0.0003 9 0 0 0 5.59E+05 2.33E+08 - - - 3.3699 0.9999 221125_WJC_METTL3_EV_vs_WT_F07.08106.08106.2 3.46E-05 13/24 K.LMELHGEGSSSGK[136.11].A "sp|P61247|RS3A_HUMAN,tr|D6R9B6|D6R9B6_HUMAN,tr|H0Y9Y4|H0Y9Y4_HUMAN,tr|D6RAT0|D6RAT0_HUMAN,tr|D6RG13|D6RG13_HUMAN" 5 1338.6329 0.88 96390 8106 2 1338.633093 670.3237 40S ribosomal protein S3a OS=Homo sapiens OX=9606 GN=RPS3A PE=1 SV=2 5.4 1813.2 - 1.59E+06 - - - 0.133 - 2.664 0.496 - 691.2 1 2 0 0.0002 13 0 0 0 2.38E+07 2.70E+07 - - - 5.2192 0.9487 221125_WJC_METTL3_EV_vs_WT_F07.08108.08108.2 6.56E-05 13/18 A.PGAEFAPNK[136.11]R[166.11].R "sp|Q15233|NONO_HUMAN,tr|A0A7I2V535|A0A7I2V535_HUMAN,tr|A0A7I2V4K9|A0A7I2V4K9_HUMAN,tr|A0A7I2V4J2|A0A7I2V4J2_HUMAN,tr|A0A7I2V5Y7|A0A7I2V5Y7_HUMAN" 5 1103.5843 0.84 96392 8108 2 1103.579752 552.7994 Non-POU domain-containing octamer-binding protein OS=Homo sapiens OX=9606 GN=NONO PE=1 SV=4 9.18 1813.3 - 1.23E+06 - - - -4.0867 - 2.498 0.522 - 1021 1 1 0 -0.0045 10 0 0 0 2.08E+07 2.47E+07 - - - 5.4505 0.9997 221125_WJC_METTL3_EV_vs_WT_F07.08111.08111.2 2.93E-06 24-Dec K.TSDVNETQPPQSE.- sp|P35580|MYH10_HUMAN 1 1430.6161 - 96395 8111 2 1430.612464 716.3153 Myosin-10 OS=Homo sapiens OX=9606 GN=MYH10 PE=1 SV=3 3.91 1813.7 - 585069 - - - -2.5639 - 2.21 0.6 - 321.1 1 2 0 -0.0037 13 0 0 0 - - - - - 5.5067 0.9998 221125_WJC_METTL3_EV_vs_WT_F07.08120.08120.2 4.39E-05 22-Oct R.AAPGAEFAPNK[136.11]R[166.11].R "sp|Q15233|NONO_HUMAN,tr|A0A7I2V535|A0A7I2V535_HUMAN,tr|A0A7I2V4K9|A0A7I2V4K9_HUMAN,tr|A0A7I2V4J2|A0A7I2V4J2_HUMAN,tr|A0A7I2V5Y7|A0A7I2V5Y7_HUMAN" 5 1245.6585 1.47 96402 8120 2 1245.656807 623.8365 Non-POU domain-containing octamer-binding protein OS=Homo sapiens OX=9606 GN=NONO PE=1 SV=4 8.79 1814.7 - 1.03E+06 - - - -1.3511 - 1.902 0.491 - 294.7 1 2 0 -0.0017 12 0 0 0 3.52E+07 2.39E+07 - - - 4.3586 1 221125_WJC_METTL3_EV_vs_WT_F07.08122.08122.2 5.13E-05 15/18 A.PGAEFAPNKR.R "sp|Q15233|NONO_HUMAN,tr|A0A7I2V535|A0A7I2V535_HUMAN,tr|A0A7I2V4K9|A0A7I2V4K9_HUMAN,tr|A0A7I2V4J2|A0A7I2V4J2_HUMAN,tr|A0A7I2V5Y7|A0A7I2V5Y7_HUMAN" 5 1085.5618 0.84 96404 8122 2 1085.560767 543.7882 Non-POU domain-containing octamer-binding protein OS=Homo sapiens OX=9606 GN=NONO PE=1 SV=4 9.18 1814.9 - 1.00E+06 - - - -0.9442 - 2.63 0.559 - 1359.9 1 1 0 -0.001 10 0 0 0 2.08E+07 2.47E+07 - - - 5.8686 0.999 221125_WJC_METTL3_EV_vs_WT_F07.08124.08124.3 7.58E-10 20/76 S.AAPGSAAPAAGSAPAAAEEK.K "sp|P05387|RLA2_HUMAN,tr|H0YDD8|H0YDD8_HUMAN" 2 1693.8271 10.57 96406 8124 3 1693.825547 565.6163 60S acidic ribosomal protein P2 OS=Homo sapiens OX=9606 GN=RPLP2 PE=1 SV=1 4.53 1815.1 - 609457 - - - -0.9334 - 3.605 0.605 - 474.8 1 1 0 -0.0016 20 0 0 0 5.84E+06 5.53E+05 - - - 8.3957 0.9998 221125_WJC_METTL3_EV_vs_WT_F07.08125.08125.2 1.74E-06 30-Aug R.SPQPVC[160.03]SPAGSEGTPK[136.11].G "sp|Q6KC79|NIPBL_HUMAN,tr|A0A590UJS4|A0A590UJS4_HUMAN" 2 1605.7548 3.21 96407 8125 2 1605.751699 803.8847 Nipped-B-like protein OS=Homo sapiens OX=9606 GN=NIPBL PE=1 SV=2 5.72 1815.3 - 270414 - - - -1.9443 - 1.955 0.566 - 171.1 1 2 0 -0.0031 16 0 0 0 1.59E+07 4.94E+06 - - - 4.8687 0.9999 221125_WJC_METTL3_EV_vs_WT_F07.08131.08131.3 0.000248 13/36 R.K[136.11]PSYAEIC[160.03]QR[166.11].T "sp|Q92615|LAR4B_HUMAN,tr|A0A087X183|A0A087X183_HUMAN,tr|H0Y4V9|H0Y4V9_HUMAN" 3 1268.6302 1.06 96411 8131 3 1268.628666 423.884 La-related protein 4B OS=Homo sapiens OX=9606 GN=LARP4B PE=1 SV=3 8.2 1815.9 - 1.79E+06 - - - -1.2305 - 2.363 0.423 - 424 1 2 0 -0.0016 10 0 0 0 1.96E+08 1.86E+08 - - - 5.767 0.9997 221125_WJC_METTL3_EV_vs_WT_F07.08133.08133.2 0.000888 28-Sep R.MFGGPGTASRPSSSR.S "sp|P08670|VIME_HUMAN,tr|B0YJC4|B0YJC4_HUMAN,tr|A0A1B0GVG8|A0A1B0GVG8_HUMAN,tr|A0A1B0GTT5|A0A1B0GTT5_HUMAN" 4 1493.7045 1.73 96413 8133 2 1493.702391 747.8595 Vimentin OS=Homo sapiens OX=9606 GN=VIM PE=1 SV=4 12 1816.2 - 627403 - - - -1.4186 - 1.816 0.459 - 40.6 1 2 0 -0.0021 15 0 0 0 1.83E+08 1.06E+08 - - - 3.8974 0.9998 221125_WJC_METTL3_EV_vs_WT_F07.08137.08137.2 1.26E-06 16-Oct K.DYGNSPLHR.F "sp|P26599|PTBP1_HUMAN,tr|A0A0U1RRM4|A0A0U1RRM4_HUMAN,tr|A6NLN1|A6NLN1_HUMAN,tr|K7ELW5|K7ELW5_HUMAN,tr|A0A0D9SF20|A0A0D9SF20_HUMAN,tr|A0A7I2V621|A0A7I2V621_HUMAN,tr|A0A087WUW5|A0A087WUW5_HUMAN" 7 1057.4941 1.16 96415 8137 2 1057.492773 529.7543 Polypyrimidine tract-binding protein 1 OS=Homo sapiens OX=9606 GN=PTBP1 PE=1 SV=1 6.74 1816.7 - 1.71E+06 - - - -1.2615 - 1.957 0.478 - 336.6 1 2 0 -0.0013 9 0 0 0 4.52E+07 3.91E+07 - - - 4.5135 1 221125_WJC_METTL3_EV_vs_WT_F07.08140.08140.2 8.49E-08 15/24 K.ETGYVVER[166.11]PSTTK[136.11].D "sp|Q9NYF8|BCLF1_HUMAN,tr|E9PKI6|E9PKI6_HUMAN,tr|A0A1W2PQ43|A0A1W2PQ43_HUMAN,tr|E9PK91|E9PK91_HUMAN,tr|E9PK09|E9PK09_HUMAN,tr|E9PQN2|E9PQN2_HUMAN" 6 1483.7637 2.19 96418 8140 2 1483.761082 742.8891 Bcl-2-associated transcription factor 1 OS=Homo sapiens OX=9606 GN=BCLAF1 PE=1 SV=2 6.24 1817 - 1.10E+06 - - - -1.7934 - 2.582 0.613 - 761.4 1 2 0 -0.0027 13 0 0 0 8.45E+08 3.86E+08 - - - 6.0023 0.9997 221125_WJC_METTL3_EV_vs_WT_F07.08141.08141.2 0.00125 16-Oct R.VTDALNATR[166.11].A "sp|P10809|CH60_HUMAN,tr|A0A7I2V2X6|A0A7I2V2X6_HUMAN,tr|A0A7I2YQK6|A0A7I2YQK6_HUMAN,tr|A0A7I2V599|A0A7I2V599_HUMAN" 4 969.5119 1.27 96419 8141 2 969.510307 485.7632 "60 kDa heat shock protein, mitochondrial OS=Homo sapiens OX=9606 GN=HSPD1 PE=1 SV=2" 5.81 1817.2 - 1.09E+06 - - - -1.6214 - 2.208 0.371 - 303.4 1 2 0 -0.0016 9 0 0 0 2.94E+07 2.31E+07 - - - 4.0723 0.9996 221125_WJC_METTL3_EV_vs_WT_F07.08147.08147.3 1.12E-06 17/48 K.AMAPLHPHPAGMR[166.11].L "sp|Q9BY77|PDIP3_HUMAN,tr|F6VRR5|F6VRR5_HUMAN,tr|F8WCX5|F8WCX5_HUMAN" 3 1394.6939 1.77 96422 8147 3 1394.689929 465.9052 Polymerase delta-interacting protein 3 OS=Homo sapiens OX=9606 GN=POLDIP3 PE=1 SV=2 9.81 1818 - 904779 - - - -2.8472 - 2.849 0.33 - 344.5 1 2 0 -0.004 13 0 0 0 3.42E+07 1.94E+07 - - - 5.0567 0.8713 221125_WJC_METTL3_EV_vs_WT_F07.08148.08148.2 0.445 14-Sep Q.DSGHLDLR[166.11].N "sp|Q86U44|MTA70_HUMAN,tr|B4E349|B4E349_HUMAN,tr|F5H6D8|F5H6D8_HUMAN,tr|B4DTN4|B4DTN4_HUMAN" 4 921.4544 0 96423 8148 2 921.451827 461.7345 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 5.21 1818 - 2.70E+06 - - - -2.7533 - 2.053 0.209 - 300.6 1 1 0 -0.0025 8 0 0 0 1.91E+05 1.08E+08 - - - 2.7533 0.8589 221125_WJC_METTL3_EV_vs_WT_F07.08153.08153.2 0.315 16-May K.EDKYEEEIK.L "sp|P67936|TPM4_HUMAN,sp|P06753|TPM3_HUMAN,sp|P07951|TPM2_HUMAN,tr|A7XZE4|A7XZE4_HUMAN,tr|A0A2R8Y5V9|A0A2R8Y5V9_HUMAN,tr|A0A5F9UN72|A0A5F9UN72_HUMAN,tr|K7EPB9|K7EPB9_HUMAN,tr|A0A2R8Y6A3|A0A2R8Y6A3_HUMAN,tr|A0A2R2Y2Q3|A0A2R2Y2Q3_HUMAN,tr|K7ENT6|K7ENT6_HUMAN,tr|J3KN67|J3KN67_HUMAN,tr|A0A2R8YH90|A0A2R8YH90_HUMAN,tr|Q5TCU3|Q5TCU3_HUMAN,tr|A0A2R8YE05|A0A2R8YE05_HUMAN,tr|U3KQK2|U3KQK2_HUMAN,tr|A0A2R8YHD2|A0A2R8YHD2_HUMAN,tr|A0A494C034|A0A494C034_HUMAN" 17 1181.5452 1.84 96426 8153 2 1181.545333 591.7799 Tropomyosin alpha-4 chain OS=Homo sapiens OX=9606 GN=TPM4 PE=1 SV=3 4.25 1818.6 - 600876 - - - 0.1134 - 1.023 0.172 - 69.6 1 2 1 0.0001 9 0 0 0 4.97E+06 2.69E+06 - - - 0.3771 0.9999 221125_WJC_METTL3_EV_vs_WT_F07.08163.08163.3 3.81E-09 18/52 K.YTAQVDAEEK[136.11]EDVK[136.11].S sp|O75947|ATP5H_HUMAN 1 1639.7912 1.4 96432 8163 3 1639.788336 547.6043 "ATP synthase subunit d, mitochondrial OS=Homo sapiens OX=9606 GN=ATP5PD PE=1 SV=3" 4.18 1819.7 - 833921 - - - -1.7441 - 3.066 0.56 - 303.8 1 2 1 -0.0029 14 0 0 0 4.46E+07 3.19E+07 - - - 7.7601 0.9618 221125_WJC_METTL3_EV_vs_WT_F07.08170.08170.2 0.0938 28-Aug R.MFGGPGTASR[166.11]PSSSR[166.11].S "sp|P08670|VIME_HUMAN,tr|B0YJC4|B0YJC4_HUMAN,tr|A0A1B0GVG8|A0A1B0GVG8_HUMAN,tr|A0A1B0GTT5|A0A1B0GTT5_HUMAN" 4 1513.7211 1.76 96436 8170 2 1513.715449 757.8678 Vimentin OS=Homo sapiens OX=9606 GN=VIM PE=1 SV=4 12 1820.6 - 2.32E+06 - - - -3.7002 - 1.514 0.165 - 29.1 3 2 0 -0.0056 15 0 0 0 1.83E+08 1.04E+08 - - - 1.0645 0.9999 221125_WJC_METTL3_EV_vs_WT_F07.08172.08172.2 0.025 18-Nov R.K[136.11]PSYAEIC[160.03]QR[166.11].T "sp|Q92615|LAR4B_HUMAN,tr|A0A087X183|A0A087X183_HUMAN,tr|H0Y4V9|H0Y4V9_HUMAN" 3 1268.6302 1.34 96438 8172 2 1268.630162 635.3224 La-related protein 4B OS=Homo sapiens OX=9606 GN=LARP4B PE=1 SV=3 8.2 1820.9 - 1.26E+06 - - - -0.0512 - 2.227 0.488 - 395.2 1 2 0 -0.0001 10 0 0 0 4.54E+07 3.38E+07 - - - 4.8802 0.9947 221125_WJC_METTL3_EV_vs_WT_F07.08175.08175.2 1.32E-07 13/28 F.YGQTLGQAQAHSQEQ.- sp|Q96I24|FUBP3_HUMAN 1 1644.7492 - 96441 8175 2 1644.748418 823.3819 Far upstream element-binding protein 3 OS=Homo sapiens OX=9606 GN=FUBP3 PE=1 SV=2 5.24 1821.3 - 479257 - - - -0.4827 - 2.638 0.559 - 558.8 1 1 0 -0.0008 15 0 0 0 - - - - - 5.5544 0.9973 221125_WJC_METTL3_EV_vs_WT_F07.08177.08177.3 0.00155 13/48 R.LAQDGAHVVVSSR[166.11].K "sp|Q9BTZ2|DHRS4_HUMAN,tr|F5GWZ1|F5GWZ1_HUMAN" 2 1347.7134 5.4 96442 8177 3 1347.70731 450.2451 Dehydrogenase\reductase SDR family member 4 OS=Homo sapiens OX=9606 GN=DHRS4 PE=1 SV=3 6.74 1821.5 - 1.10E+06 - - - -4.5425 - 2.3 0.326 - 207.9 1 2 0 -0.0061 13 0 0 0 5.62E+07 1.04E+07 - - - 4.4311 0.9999 221125_WJC_METTL3_EV_vs_WT_F07.08180.08180.3 0.00688 18/48 K.TAMEVEAPSK[136.11]PAR[166.11].T sp|E9PRG8|CK098_HUMAN 1 1403.7198 2.24 96444 8180 3 1403.716549 468.9139 Uncharacterized protein C11orf98 OS=Homo sapiens OX=9606 GN=C11orf98 PE=4 SV=2 5.81 1821.8 - 1.56E+06 - - - -2.2946 - 3.099 0.473 - 518.1 1 2 0 -0.0032 13 0 0 0 1.20E+08 5.37E+07 - - - 6.8793 1 221125_WJC_METTL3_EV_vs_WT_F07.08184.08184.2 4.44E-07 24-Dec K.SSLSNNEC[160.03]GSLDK[136.11].T sp|Q5UIP0|RIF1_HUMAN 1 1417.6235 0.91 96446 8184 2 1417.622966 709.819 Telomere-associated protein RIF1 OS=Homo sapiens OX=9606 GN=RIF1 PE=1 SV=2 4.37 1822.3 - 483448 - - - -0.3576 - 2.79 0.595 - 615.1 1 2 0 -0.0005 13 0 0 0 5.90E+06 6.45E+06 - - - 6.0689 0.9999 221125_WJC_METTL3_EV_vs_WT_F07.08185.08185.2 0.00299 18-Nov R.K[136.11]EQELTQAIK[136.11].K sp|Q9H501|ESF1_HUMAN 1 1202.6842 0.94 96447 8185 2 1202.683415 602.3494 ESF1 homolog OS=Homo sapiens OX=9606 GN=ESF1 PE=1 SV=1 6.14 1822.4 - 0 - - - -0.6128 - 2.537 0.407 - 373 1 2 0 -0.0007 10 0 0 0 1.62E+07 1.72E+07 - - - 4.6455 1 221125_WJC_METTL3_EV_vs_WT_F07.08186.08186.2 9.75E-06 13/20 T.GYVVERPSTTK.D "sp|Q9NYF8|BCLF1_HUMAN,tr|E9PKI6|E9PKI6_HUMAN,tr|A0A1W2PQ43|A0A1W2PQ43_HUMAN,tr|E9PK91|E9PK91_HUMAN,tr|E9PK09|E9PK09_HUMAN,tr|E9PQN2|E9PQN2_HUMAN" 6 1235.651 2.44 96448 8186 2 1235.655119 618.8328 Bcl-2-associated transcription factor 1 OS=Homo sapiens OX=9606 GN=BCLAF1 PE=1 SV=2 8.59 1822.5 - 1.72E+06 - - - 3.3327 - 2.659 0.584 - 288.9 1 1 0 0.0041 11 0 0 0 1.47E+08 6.00E+07 - - - 5.9987 0.9999 221125_WJC_METTL3_EV_vs_WT_F07.08190.08190.3 1.06E-07 19/52 K.YTAQVDAEEKEDVK.S sp|O75947|ATP5H_HUMAN 1 1623.7628 1.4 96451 8190 3 1623.761102 542.2615 "ATP synthase subunit d, mitochondrial OS=Homo sapiens OX=9606 GN=ATP5PD PE=1 SV=3" 4.18 1823 - 2.04E+06 - - - -1.0433 - 3.452 0.561 - 367 1 2 1 -0.0017 14 0 0 0 4.46E+07 3.19E+07 - - - 8.0867 0.9999 221125_WJC_METTL3_EV_vs_WT_F07.08192.08192.3 0.00121 14/36 R.DAPQDFHPDR.V "sp|P21333|FLNA_HUMAN,tr|A0A7P0NMY4|A0A7P0NMY4_HUMAN,tr|Q60FE5|Q60FE5_HUMAN" 3 1196.5211 1.19 96452 8192 3 1196.517789 399.8476 Filamin-A OS=Homo sapiens OX=9606 GN=FLNA PE=1 SV=4 4.41 1823.2 - 1.86E+06 - - - -2.7254 - 1.935 0.52 - 245.9 1 2 0 -0.0033 10 0 0 0 7.69E+07 6.46E+07 - - - 6.2644 0.9999 221125_WJC_METTL3_EV_vs_WT_F07.08194.08194.3 0.000513 Dec-48 R.EGVGPVEQEGVRR.A sp|Q969Y2|GTPB3_HUMAN 1 1410.7215 1.99 96454 8194 3 1410.721306 471.2478 "tRNA modification GTPase GTPBP3, mitochondrial OS=Homo sapiens OX=9606 GN=GTPBP3 PE=1 SV=2" 4.79 1823.4 - 1.36E+06 - - - -0.1666 - 2.375 0.388 - 237.6 1 2 0 -0.0002 13 0 0 0 3.63E+07 1.83E+07 - - - 5.211 1 221125_WJC_METTL3_EV_vs_WT_F07.08196.08196.2 1.08E-08 16/22 E.TGYVVERPSTTK.D "sp|Q9NYF8|BCLF1_HUMAN,tr|E9PKI6|E9PKI6_HUMAN,tr|A0A1W2PQ43|A0A1W2PQ43_HUMAN,tr|E9PK91|E9PK91_HUMAN,tr|E9PK09|E9PK09_HUMAN,tr|E9PQN2|E9PQN2_HUMAN" 6 1336.6987 2.5 96456 8196 2 1336.697876 669.3566 Bcl-2-associated transcription factor 1 OS=Homo sapiens OX=9606 GN=BCLAF1 PE=1 SV=2 8.26 1823.6 - 805409 - - - -0.6015 - 2.702 0.611 - 660.6 1 1 0 -0.0008 12 0 0 0 5.41E+07 2.17E+07 - - - 6.169 0.9999 221125_WJC_METTL3_EV_vs_WT_F07.08200.08200.2 0.753 14/18 R.KEQELTQAIK.K sp|Q9H501|ESF1_HUMAN 1 1186.6558 0.94 96460 8200 2 1186.65528 594.3352 ESF1 homolog OS=Homo sapiens OX=9606 GN=ESF1 PE=1 SV=1 6.14 1824.2 - 538063 - - - -0.3978 - 3.018 0.413 - 701.6 1 2 0 -0.0005 10 0 0 0 1.62E+07 1.72E+07 - - - 5.1745 0.9999 221125_WJC_METTL3_EV_vs_WT_F07.08205.08205.3 5.51E-05 16/56 K.VASLEESEGNKQDLK.A sp|Q07065|CKAP4_HUMAN 1 1645.8159 1.49 96463 8205 3 1645.812878 549.6126 Cytoskeleton-associated protein 4 OS=Homo sapiens OX=9606 GN=CKAP4 PE=1 SV=2 4.41 1824.8 - 1.61E+06 - - - -1.8331 - 3.473 0.502 - 349.2 1 2 1 -0.003 15 0 0 0 1.03E+08 6.94E+07 - - - 7.3847 0.9997 221125_WJC_METTL3_EV_vs_WT_F07.08212.08212.3 1.68E-05 15/56 K.VASLEESEGNK[136.11]QDLK[136.11].A sp|Q07065|CKAP4_HUMAN 1 1661.8443 1.49 96468 8212 3 1661.840997 554.9554 Cytoskeleton-associated protein 4 OS=Homo sapiens OX=9606 GN=CKAP4 PE=1 SV=2 4.41 1825.6 - 2.17E+06 - - - -1.9845 - 3.256 0.425 - 263.1 1 2 1 -0.0033 15 0 0 0 1.03E+08 6.94E+07 - - - 6.3578 0.9995 221125_WJC_METTL3_EV_vs_WT_F07.08213.08213.3 0.00153 Nov-48 K.TAMEVEAPSKPAR.T sp|E9PRG8|CK098_HUMAN 1 1385.6973 4.54 96469 8213 3 1385.696854 462.9064 Uncharacterized protein C11orf98 OS=Homo sapiens OX=9606 GN=C11orf98 PE=4 SV=2 5.81 1825.6 - 1.23E+06 - - - -0.3219 - 2.069 0.297 - 144.6 1 2 0 -0.0004 13 0 0 0 8.19E+07 1.80E+07 - - - 3.8224 0.9598 221125_WJC_METTL3_EV_vs_WT_F07.08215.08215.3 0.062 Dec-36 R.ER[166.11]LEQEQLER[166.11].E "sp|Q8N8S7|ENAH_HUMAN,tr|A0A0U1RQP7|A0A0U1RQP7_HUMAN,tr|A0A075B6E5|A0A075B6E5_HUMAN,tr|A0A0U1RRM6|A0A0U1RRM6_HUMAN" 4 1348.685 1.23 96471 8215 3 1348.678499 450.5689 Protein enabled homolog OS=Homo sapiens OX=9606 GN=ENAH PE=1 SV=2 4.49 1825.8 - 1.52E+06 - - - -4.8069 - 2.502 0.216 - 360.2 1 2 1 -0.0065 10 0 0 0 5.11E+07 4.15E+07 - - - 3.6247 0.9603 221125_WJC_METTL3_EV_vs_WT_F07.08216.08216.2 0.702 16-Jul K.TLHMDFEQK.Y "sp|Q02224|CENPE_HUMAN,tr|A0A087X0P0|A0A087X0P0_HUMAN" 2 1147.5332 2.78 96472 8216 2 1147.534213 574.7739 Centromere-associated protein E OS=Homo sapiens OX=9606 GN=CENPE PE=1 SV=2 5.29 1825.9 - 1.20E+06 - - - 0.888 - 1.269 0.017 - 190.4 1 2 0 0.001 9 0 0 0 2.03E+07 7.30E+06 - - - -0.1445 0.9968 221125_WJC_METTL3_EV_vs_WT_F07.08217.08217.3 0.318 14/40 K.LSHRPQPELLK.S sp|Q99583|MNT_HUMAN 1 1316.7565 3.44 96473 8217 3 1316.753926 439.9261 Max-binding protein MNT OS=Homo sapiens OX=9606 GN=MNT PE=1 SV=1 8.75 1826 - 840248 - - - -1.932 - 2.105 0.199 - 230 1 2 0 -0.0025 11 0 0 0 9.07E+06 2.63E+06 - - - 2.8724 0.9965 221125_WJC_METTL3_EV_vs_WT_F07.08222.08222.3 0.000159 15/36 R.ERLEQEQLER.E "sp|Q8N8S7|ENAH_HUMAN,tr|A0A0U1RQP7|A0A0U1RQP7_HUMAN,tr|A0A075B6E5|A0A075B6E5_HUMAN,tr|A0A0U1RRM6|A0A0U1RRM6_HUMAN" 4 1328.6684 1.22 96476 8222 3 1328.666926 443.8968 Protein enabled homolog OS=Homo sapiens OX=9606 GN=ENAH PE=1 SV=2 4.49 1826.6 - 2.06E+06 - - - -1.141 - 2.452 0.215 - 541.9 1 2 1 -0.0015 10 0 0 0 5.06E+07 4.15E+07 - - - 3.556 0.9992 221125_WJC_METTL3_EV_vs_WT_F07.08224.08224.2 2.62E-05 16-Sep R.HENYDEALR[166.11].L sp|Q9HCS7|SYF1_HUMAN 1 1155.5184 0.62 96478 8224 2 1155.515221 578.7665 Pre-mRNA-splicing factor SYF1 OS=Homo sapiens OX=9606 GN=XAB2 PE=1 SV=2 4.65 1826.8 - 946810 - - - -2.7693 - 1.817 0.434 - 206.5 1 2 0 -0.0032 9 0 0 0 1.92E+07 3.10E+07 - - - 3.9732 0.984 221125_WJC_METTL3_EV_vs_WT_F07.08229.08229.3 0.276 Aug-32 R.HEHQVMLMR[166.11].Q "sp|Q15233|NONO_HUMAN,tr|A0A7I2V535|A0A7I2V535_HUMAN,tr|A0A7I2V4N2|A0A7I2V4N2_HUMAN,tr|A0A7I2V4K9|A0A7I2V4K9_HUMAN,tr|A0A7I2V464|A0A7I2V464_HUMAN,tr|A0A7P0MRW0|A0A7P0MRW0_HUMAN,tr|H7C367|H7C367_HUMAN,tr|A0A7I2V4J2|A0A7I2V4J2_HUMAN,tr|A0A7I2V5Y7|A0A7I2V5Y7_HUMAN,tr|C9JYS8|C9JYS8_HUMAN" 10 1189.5724 0.69 96482 8229 3 1189.569165 397.5314 Non-POU domain-containing octamer-binding protein OS=Homo sapiens OX=9606 GN=NONO PE=1 SV=4 6.92 1827.4 - 672391 - - - -2.7085 - 1.568 0.206 - 92.1 1 2 0 -0.0032 9 0 0 0 9.90E+07 1.44E+08 - - - 2.1914 0.9822 221125_WJC_METTL3_EV_vs_WT_F07.08232.08232.2 0.0141 13/18 G.YVVERPSTTK.D "sp|Q9NYF8|BCLF1_HUMAN,tr|E9PKI6|E9PKI6_HUMAN,tr|A0A1W2PQ43|A0A1W2PQ43_HUMAN,tr|E9PK91|E9PK91_HUMAN,tr|E9PK09|E9PK09_HUMAN,tr|E9PQN2|E9PQN2_HUMAN" 6 1178.6295 2.46 96484 8232 2 1178.629301 590.322 Bcl-2-associated transcription factor 1 OS=Homo sapiens OX=9606 GN=BCLAF1 PE=1 SV=2 8.59 1827.7 - 476916 - - - -0.2011 - 1.919 0.366 - 354.3 1 1 0 -0.0002 10 0 0 0 1.85E+07 7.53E+06 - - - 3.5636 1 221125_WJC_METTL3_EV_vs_WT_F07.08233.08233.2 7.84E-06 17/22 E.TGYVVER[166.11]PSTTK[136.11].D "sp|Q9NYF8|BCLF1_HUMAN,tr|E9PKI6|E9PKI6_HUMAN,tr|A0A1W2PQ43|A0A1W2PQ43_HUMAN,tr|E9PK91|E9PK91_HUMAN,tr|E9PK09|E9PK09_HUMAN,tr|E9PQN2|E9PQN2_HUMAN" 6 1354.7212 2.53 96485 8233 2 1354.720283 678.3679 Bcl-2-associated transcription factor 1 OS=Homo sapiens OX=9606 GN=BCLAF1 PE=1 SV=2 8.26 1827.9 - 610982 - - - -0.64 - 3.312 0.511 - 731.7 1 1 0 -0.0009 12 0 0 0 5.41E+07 2.14E+07 - - - 5.9659 0.9991 221125_WJC_METTL3_EV_vs_WT_F07.08234.08234.3 0.0364 15/44 R.QGLQTTQAHLER.L "sp|Q14C86|GAPD1_HUMAN,tr|F8W9S7|F8W9S7_HUMAN" 2 1380.711 0.69 96486 8234 3 1380.712223 461.2443 GTPase-activating protein and VPS9 domain-containing protein 1 OS=Homo sapiens OX=9606 GN=GAPVD1 PE=1 SV=2 6.75 1828 - 1.38E+06 - - - 0.9032 - 2.113 0.251 - 213.3 1 2 0 0.0012 12 0 0 0 1.48E+07 2.14E+07 - - - 3.4117 0.9999 221125_WJC_METTL3_EV_vs_WT_F07.08244.08244.3 4.56E-05 Nov-52 K.SLTK[136.11]PLAENEEGEK[136.11].Q "sp|Q9NRY5|F1142_HUMAN,tr|E7ESJ7|E7ESJ7_HUMAN" 2 1559.8014 1.37 96492 8244 3 1559.799683 520.9411 Protein FAM114A2 OS=Homo sapiens OX=9606 GN=FAM114A2 PE=1 SV=4 4.49 1829.1 - 805720 - - - -1.0796 - 2.159 0.431 - 82 1 2 0 -0.0017 14 0 0 0 4.17E+07 3.04E+07 - - - 5.3901 1 221125_WJC_METTL3_EV_vs_WT_F07.08245.08245.2 1.23E-06 14/20 T.GYVVER[166.11]PSTTK[136.11].D "sp|Q9NYF8|BCLF1_HUMAN,tr|E9PKI6|E9PKI6_HUMAN,tr|A0A1W2PQ43|A0A1W2PQ43_HUMAN,tr|E9PK91|E9PK91_HUMAN,tr|E9PK09|E9PK09_HUMAN,tr|E9PQN2|E9PQN2_HUMAN" 6 1253.6735 2.44 96493 8245 2 1253.673402 627.844 Bcl-2-associated transcription factor 1 OS=Homo sapiens OX=9606 GN=BCLAF1 PE=1 SV=2 8.59 1829.3 - 1.09E+06 - - - -0.055 - 2.716 0.604 - 647.6 1 1 0 -0.0001 11 0 0 0 1.47E+08 6.00E+07 - - - 6.2051 0.9562 221125_WJC_METTL3_EV_vs_WT_F07.08246.08246.3 2.83 Aug-36 K.FQHPSHELLK.E "sp|Q6PKG0|LARP1_HUMAN,sp|Q659C4|LAR1B_HUMAN,tr|A0A3B3ISF0|A0A3B3ISF0_HUMAN" 3 1234.6459 1.12 96494 8246 3 1234.644898 412.5559 La-related protein 1 OS=Homo sapiens OX=9606 GN=LARP1 PE=1 SV=2 6.92 1829.3 - 1.09E+06 - - - -0.7759 - 1.177 0.172 - 65.4 1 2 0 -0.001 10 0 0 0 4.39E+07 3.93E+07 - - - 0.9333 0.9998 221125_WJC_METTL3_EV_vs_WT_F07.08247.08247.3 3.60E-06 16/60 R.EGVLTGSPEQK[136.11]EEAAK[136.11].A sp|Q92616|GCN1_HUMAN 1 1687.8599 0.92 96495 8247 3 1687.85612 563.6273 eIF-2-alpha kinase activator GCN1 OS=Homo sapiens OX=9606 GN=GCN1 PE=1 SV=6 4.49 1829.4 - 563942 - - - -2.2662 - 3.14 0.493 - 411.7 1 2 1 -0.0038 16 0 0 0 1.30E+07 1.42E+07 - - - 6.9713 0.9986 221125_WJC_METTL3_EV_vs_WT_F07.08248.08248.2 5.28E-05 20-Nov R.K[136.11]LEEDDQAK[136.11]DI.- "sp|O95619|YETS4_HUMAN,tr|F8W0J4|F8W0J4_HUMAN" 2 1318.6587 1.38 96496 8248 2 1318.658694 660.3366 YEATS domain-containing protein 4 OS=Homo sapiens OX=9606 GN=YEATS4 PE=1 SV=1 4.11 1829.6 - 404327 - - - -0.0243 - 2.062 0.518 - 241.8 1 2 1 0 11 0 0 0 3.69E+07 2.66E+07 - - - 4.8247 0.8043 221125_WJC_METTL3_EV_vs_WT_F07.08251.08251.2 0.0431 14-Nov V.VERPSTTK.D "sp|Q9NYF8|BCLF1_HUMAN,tr|E9PKI6|E9PKI6_HUMAN,tr|A0A1W2PQ43|A0A1W2PQ43_HUMAN,tr|E9PK91|E9PK91_HUMAN,tr|E9PK09|E9PK09_HUMAN,tr|E9PQN2|E9PQN2_HUMAN" 6 916.4978 1.25 96497 8251 2 916.494252 459.2562 Bcl-2-associated transcription factor 1 OS=Homo sapiens OX=9606 GN=BCLAF1 PE=1 SV=2 8.72 1830 - 2.60E+06 - - - -3.8658 - 2.153 0.232 - 485.2 1 1 0 -0.0035 8 0 0 0 5.95E+07 4.76E+07 - - - 3.0663 1 221125_WJC_METTL3_EV_vs_WT_F07.08252.08252.2 1.12E-05 15/20 R.KLEEDDQAKDI.- "sp|O95619|YETS4_HUMAN,tr|F8W0J4|F8W0J4_HUMAN" 2 1302.6303 1.38 96498 8252 2 1302.632239 652.3224 YEATS domain-containing protein 4 OS=Homo sapiens OX=9606 GN=YEATS4 PE=1 SV=1 4.11 1830.1 - 633552 - - - 1.4686 - 2.713 0.566 - 500.5 1 2 1 0.0019 11 0 0 0 3.69E+07 2.66E+07 - - - 5.9208 0.9997 221125_WJC_METTL3_EV_vs_WT_F07.08256.08256.3 3.75E-06 13/36 K.FQHPSHELLK[136.11].E "sp|Q6PKG0|LARP1_HUMAN,sp|Q659C4|LAR1B_HUMAN,tr|A0A3B3ISF0|A0A3B3ISF0_HUMAN" 3 1242.6601 1.12 96502 8256 3 1242.655141 415.2273 La-related protein 1 OS=Homo sapiens OX=9606 GN=LARP1 PE=1 SV=2 6.92 1830.5 - 794303 - - - -3.9552 - 2.225 0.473 - 162.4 1 2 0 -0.0049 10 0 0 0 4.61E+07 4.10E+07 - - - 6.1478 0.9998 221125_WJC_METTL3_EV_vs_WT_F07.08260.08260.3 0.000109 Dec-40 K.SETELKDTYAR.W "sp|Q13200|PSMD2_HUMAN,tr|H7C1H2|H7C1H2_HUMAN" 2 1311.6307 0.54 96504 8260 3 1311.628612 438.2175 26S proteasome non-ATPase regulatory subunit 2 OS=Homo sapiens OX=9606 GN=PSMD2 PE=1 SV=3 4.68 1831 - 1.25E+06 - - - -1.5614 - 2.337 0.493 - 268.9 1 2 1 -0.002 11 0 0 0 3.76E+07 7.00E+07 - - - 6.4474 0.9987 221125_WJC_METTL3_EV_vs_WT_F07.08262.08262.3 0.00481 Sep-48 K.LK[136.11]PAHEGLVATVK[136.11].E "sp|Q9Y618|NCOR2_HUMAN,tr|C9JQE8|C9JQE8_HUMAN,tr|C9J7T7|C9J7T7_HUMAN,tr|C9JE98|C9JE98_HUMAN,tr|C9J0Q5|C9J0Q5_HUMAN,tr|A0A384DVL6|A0A384DVL6_HUMAN" 6 1377.8315 1.97 96506 8262 3 1377.828662 460.2844 Nuclear receptor corepressor 2 OS=Homo sapiens OX=9606 GN=NCOR2 PE=1 SV=3 8.6 1831.3 - 891174 - - - -2.0489 - 1.798 0.311 - 44.3 1 2 0 -0.0028 13 0 0 0 2.73E+07 1.39E+07 - - - 3.5972 0.9724 221125_WJC_METTL3_EV_vs_WT_F07.08264.08264.2 0.00208 18-Sep G.YVVER[166.11]PSTTK[136.11].D "sp|Q9NYF8|BCLF1_HUMAN,tr|E9PKI6|E9PKI6_HUMAN,tr|A0A1W2PQ43|A0A1W2PQ43_HUMAN,tr|E9PK91|E9PK91_HUMAN,tr|E9PK09|E9PK09_HUMAN,tr|E9PQN2|E9PQN2_HUMAN" 6 1196.652 2.46 96508 8264 2 1196.651907 599.3333 Bcl-2-associated transcription factor 1 OS=Homo sapiens OX=9606 GN=BCLAF1 PE=1 SV=2 8.59 1831.6 - 313614 - - - -0.0844 - 1.701 0.345 - 221.3 1 1 0 -0.0001 10 0 0 0 1.85E+07 7.53E+06 - - - 3.0719 0.9977 221125_WJC_METTL3_EV_vs_WT_F07.08265.08265.2 0.286 18-Jun R.K[136.11]VIDDTNITR[166.11].L "sp|P05783|K1C18_HUMAN,tr|F8VZY9|F8VZY9_HUMAN" 2 1191.6578 1.87 96509 8265 2 1191.656688 596.8362 "Keratin, type I cytoskeletal 18 OS=Homo sapiens OX=9606 GN=KRT18 PE=1 SV=2" 5.96 1831.7 - 0 - - - -0.9508 - 1.385 0.25 - 116.4 1 2 0 -0.0011 10 0 0 0 1.60E+07 8.57E+06 - - - 1.7963 0.9993 221125_WJC_METTL3_EV_vs_WT_F07.08269.08269.2 0.00694 20-Sep R.ADTQTYQPYNK.D sp|P84090|ERH_HUMAN 1 1327.6044 2.4 96511 8269 2 1327.60171 664.8095 Enhancer of rudimentary homolog OS=Homo sapiens OX=9606 GN=ERH PE=1 SV=1 5.88 1832.2 - 1.74E+06 - - - -2.0601 - 1.767 0.392 - 259.6 1 2 0 -0.0027 11 0 0 0 5.34E+09 2.23E+09 - - - 3.4755 1 221125_WJC_METTL3_EV_vs_WT_F07.08270.08270.3 5.96E-07 13/44 K.R[166.11]AGELTEDEVER[166.11].V sp|P62269|RS18_HUMAN 1 1422.6854 0.99 96512 8270 3 1422.684163 475.2357 40S ribosomal protein S18 OS=Homo sapiens OX=9606 GN=RPS18 PE=1 SV=3 4.25 1832.2 - 902635 - - - -0.8526 - 2.462 0.519 - 321.6 1 2 0 -0.0012 12 0 0 0 4.23E+08 4.26E+08 - - - 6.8234 0.9998 221125_WJC_METTL3_EV_vs_WT_F07.08271.08271.3 6.89E-06 17/60 R.EGVLTGSPEQKEEAAK.A sp|Q92616|GCN1_HUMAN 1 1671.8315 0.92 96513 8271 3 1671.82803 558.2845 eIF-2-alpha kinase activator GCN1 OS=Homo sapiens OX=9606 GN=GCN1 PE=1 SV=6 4.49 1832.3 - 564472 - - - -2.1025 - 2.92 0.484 - 420 1 2 1 -0.0035 16 0 0 0 1.30E+07 1.42E+07 - - - 6.6847 0.9996 221125_WJC_METTL3_EV_vs_WT_F07.08272.08272.2 0.147 18-Oct R.KVIDDTNITR.L "sp|P05783|K1C18_HUMAN,tr|F8VZY9|F8VZY9_HUMAN" 2 1173.6354 1.43 96514 8272 2 1173.636692 587.825 "Keratin, type I cytoskeletal 18 OS=Homo sapiens OX=9606 GN=KRT18 PE=1 SV=2" 5.96 1832.5 - 495630 - - - 1.1426 - 2.21 0.309 - 326.6 1 2 0 0.0013 10 0 0 0 1.61E+07 1.13E+07 - - - 3.5363 0.9467 221125_WJC_METTL3_EV_vs_WT_F07.08273.08273.3 0.000556 13/44 E.TGYVVERPSTTK.D "sp|Q9NYF8|BCLF1_HUMAN,tr|E9PKI6|E9PKI6_HUMAN,tr|A0A1W2PQ43|A0A1W2PQ43_HUMAN,tr|E9PK91|E9PK91_HUMAN,tr|E9PK09|E9PK09_HUMAN,tr|E9PQN2|E9PQN2_HUMAN" 6 1336.6987 2.62 96515 8273 3 1336.70062 446.5735 Bcl-2-associated transcription factor 1 OS=Homo sapiens OX=9606 GN=BCLAF1 PE=1 SV=2 8.26 1832.6 - 490051 - - - 1.4513 - 2.134 0.304 - 170.7 1 1 0 0.0019 12 0 0 0 6.61E+06 2.53E+06 - - - 4.0298 0.9999 221125_WJC_METTL3_EV_vs_WT_F07.08278.08278.3 4.71E-05 Dec-44 K.RAGELTEDEVER.V sp|P62269|RS18_HUMAN 1 1402.6688 0.99 96518 8278 3 1402.666216 468.5636 40S ribosomal protein S18 OS=Homo sapiens OX=9606 GN=RPS18 PE=1 SV=3 4.25 1833.2 - 2.62E+06 - - - -1.8679 - 2.695 0.455 - 259.8 1 2 0 -0.0026 12 0 0 0 4.23E+08 4.29E+08 - - - 6.3601 0.9992 221125_WJC_METTL3_EV_vs_WT_F07.08279.08279.2 0.00202 20-Sep R.ADTQTYQPYNK[136.11].D sp|P84090|ERH_HUMAN 1 1335.6186 2.4 96519 8279 2 1335.616318 668.8166 Enhancer of rudimentary homolog OS=Homo sapiens OX=9606 GN=ERH PE=1 SV=1 5.88 1833.3 - 2.11E+06 - - - -1.7423 - 1.384 0.429 - 258.7 1 2 0 -0.0023 11 0 0 0 5.34E+09 2.23E+09 - - - 3.088 0.9997 221125_WJC_METTL3_EV_vs_WT_F07.08280.08280.2 0.00339 22-Nov K.R[166.11]AGELTEDEVER[166.11].V sp|P62269|RS18_HUMAN 1 1422.6854 0.97 96520 8280 2 1422.685871 712.35 40S ribosomal protein S18 OS=Homo sapiens OX=9606 GN=RPS18 PE=1 SV=3 4.25 1833.4 - 386290 - - - 0.3479 - 2.185 0.338 - 117 1 2 0 0.0005 12 0 0 0 8.61E+07 8.86E+07 - - - 3.5939 0.9998 221125_WJC_METTL3_EV_vs_WT_F07.08285.08285.2 2.83E-06 24-Nov R.SAAVSEQQQLEQK.T "sp|O75376|NCOR1_HUMAN,tr|E7EVK1|E7EVK1_HUMAN,tr|A0A088AWL3|A0A088AWL3_HUMAN" 3 1444.7158 3.83 96523 8285 2 1444.714484 723.3652 Nuclear receptor corepressor 1 OS=Homo sapiens OX=9606 GN=NCOR1 PE=1 SV=2 4.53 1834.1 - 298851 - - - -0.9019 - 2.425 0.451 - 364 1 2 0 -0.0013 13 0 0 0 1.13E+07 2.94E+06 - - - 4.6452 0.816 221125_WJC_METTL3_EV_vs_WT_F07.08288.08288.2 1.18 26-May R.REVQSESAQEPGAR.D tr|A8MTF4|A8MTF4_HUMAN 1 1542.7386 4.35 96524 8288 2 1542.736037 772.3766 Baculoviral IAP repeat-containing protein 7 OS=Homo sapiens OX=9606 GN=BIRC7 PE=4 SV=1 4.79 1834.5 - 548639 - - - -1.6918 - 1.079 0.031 - 23 10 2 0 -0.0026 14 0 0 0 1.06E+07 2.44E+06 - - - -0.9867 0.9996 221125_WJC_METTL3_EV_vs_WT_F07.08294.08294.2 1.05E-05 16/22 K.RAGELTEDEVER.V sp|P62269|RS18_HUMAN 1 1402.6688 0.97 96529 8294 2 1402.664921 702.3417 40S ribosomal protein S18 OS=Homo sapiens OX=9606 GN=RPS18 PE=1 SV=3 4.25 1835.1 - 1.42E+06 - - - -2.7911 - 2.965 0.436 - 339.8 1 2 0 -0.0039 12 0 0 0 8.61E+07 8.86E+07 - - - 5.1198 0.9995 221125_WJC_METTL3_EV_vs_WT_F07.08298.08298.2 0.00566 22-Oct R.SPSPAHLPDDPK.V "sp|Q92615|LAR4B_HUMAN,tr|A0A087X183|A0A087X183_HUMAN,tr|H0Y641|H0Y641_HUMAN,tr|H0Y4V9|H0Y4V9_HUMAN" 4 1259.6146 0.17 96531 8298 2 1259.61427 630.8146 La-related protein 4B OS=Homo sapiens OX=9606 GN=LARP4B PE=1 SV=3 5.19 1835.7 - 275048 - - - -0.2747 - 1.513 0.382 - 214.8 1 2 0 -0.0003 12 0 0 0 3.97E+06 2.30E+07 - - - 2.9519 0.9999 221125_WJC_METTL3_EV_vs_WT_F07.08301.08301.2 0.000144 20-Nov K.ESQTQDNITVR[166.11].W sp|Q92900|RENT1_HUMAN 1 1299.6294 1.17 96533 8301 2 1299.62779 650.822 Regulator of nonsense transcripts 1 OS=Homo sapiens OX=9606 GN=UPF1 PE=1 SV=2 4.37 1835.9 - 1.68E+06 - - - -1.2604 - 2.338 0.509 - 612.5 1 2 0 -0.0016 11 0 0 0 4.26E+07 3.63E+07 - - - 5.0975 0.9998 221125_WJC_METTL3_EV_vs_WT_F07.08302.08302.2 2.11E-06 24-Nov R.SAAVSEQQQLEQK[136.11].T "sp|O75376|NCOR1_HUMAN,tr|E7EVK1|E7EVK1_HUMAN,tr|A0A088AWL3|A0A088AWL3_HUMAN" 3 1452.73 3.51 96534 8302 2 1452.732772 727.3723 Nuclear receptor corepressor 1 OS=Homo sapiens OX=9606 GN=NCOR1 PE=1 SV=2 4.53 1836.1 - 268158 - - - 1.9171 - 2.365 0.576 - 327.2 1 2 0 0.0028 13 0 0 0 1.03E+07 2.94E+06 - - - 5.5037 0.9992 221125_WJC_METTL3_EV_vs_WT_F07.08309.08309.3 0.000104 14/40 K.NILNKPEVNQK.L "sp|P52732|KIF11_HUMAN,tr|A0A7I2YQY4|A0A7I2YQY4_HUMAN,tr|A0A7I2V3A9|A0A7I2V3A9_HUMAN,tr|A0A7I2V3V3|A0A7I2V3V3_HUMAN" 4 1295.7197 4.83 96539 8309 3 1295.718372 432.9139 Kinesin-like protein KIF11 OS=Homo sapiens OX=9606 GN=KIF11 PE=1 SV=2 8.59 1836.8 - 1.02E+06 - - - -1.0635 - 2.203 0.247 - 187.8 1 2 0 -0.0014 11 0 0 0 3.52E+09 7.30E+08 - - - 3.5372 0.9997 221125_WJC_METTL3_EV_vs_WT_F07.08310.08310.2 1.20E-05 16-Nov K.HFTEDIQTR[166.11].Q "sp|Q96SB4|SRPK1_HUMAN,sp|Q9UPE1|SRPK3_HUMAN,sp|P78362|SRPK2_HUMAN,tr|H7C5L6|H7C5L6_HUMAN,tr|H7C2I2|H7C2I2_HUMAN,tr|H3BLV9|H3BLV9_HUMAN,tr|A8MPP7|A8MPP7_HUMAN,tr|A8MPY5|A8MPY5_HUMAN,tr|E7ETV6|E7ETV6_HUMAN,tr|H7C521|H7C521_HUMAN" 10 1155.5548 0.77 96540 8310 2 1155.551935 578.7847 SRSF protein kinase 1 OS=Homo sapiens OX=9606 GN=SRPK1 PE=1 SV=2 5.32 1836.9 - 311413 - - - -2.4845 - 1.988 0.608 - 366 1 2 0 -0.0029 9 0 0 0 1.92E+07 2.48E+07 - - - 5.5187 0.9997 221125_WJC_METTL3_EV_vs_WT_F07.08311.08311.2 0.00203 16-Sep K.HFTEDIQTR.Q "sp|Q96SB4|SRPK1_HUMAN,sp|Q9UPE1|SRPK3_HUMAN,sp|P78362|SRPK2_HUMAN,tr|H7C5L6|H7C5L6_HUMAN,tr|H7C2I2|H7C2I2_HUMAN,tr|H3BLV9|H3BLV9_HUMAN,tr|A8MPP7|A8MPP7_HUMAN,tr|A8MPY5|A8MPY5_HUMAN,tr|E7ETV6|E7ETV6_HUMAN,tr|H7C521|H7C521_HUMAN" 10 1145.5465 0.78 96541 8311 2 1145.545654 573.7805 SRSF protein kinase 1 OS=Homo sapiens OX=9606 GN=SRPK1 PE=1 SV=2 5.32 1837.1 - 202292 - - - -0.7699 - 1.795 0.421 - 271.3 1 2 0 -0.0009 9 0 0 0 1.92E+07 2.47E+07 - - - 3.8427 0.9999 221125_WJC_METTL3_EV_vs_WT_F07.08314.08314.3 0.000252 13/36 R.KPSYAEIC[160.03]QR.T "sp|Q92615|LAR4B_HUMAN,tr|A0A087X183|A0A087X183_HUMAN,tr|H0Y4V9|H0Y4V9_HUMAN" 3 1250.6078 0.73 96543 8314 3 1250.605713 417.8765 La-related protein 4B OS=Homo sapiens OX=9606 GN=LARP4B PE=1 SV=3 8.2 1837.4 - 1.07E+06 - - - -1.6344 - 2.563 0.357 - 402.7 1 2 0 -0.002 10 0 0 0 2.39E+08 3.26E+08 - - - 5.2683 0.9998 221125_WJC_METTL3_EV_vs_WT_F07.08316.08316.3 0.00223 Sep-40 R.ADTQTYQPYNK.D sp|P84090|ERH_HUMAN 1 1327.6044 2.53 96544 8316 3 1327.60414 443.5421 Enhancer of rudimentary homolog OS=Homo sapiens OX=9606 GN=ERH PE=1 SV=1 5.88 1837.6 - 828478 - - - -0.2297 - 2.007 0.347 - 90.6 1 2 0 -0.0003 11 0 0 0 1.23E+08 4.87E+07 - - - 4.3877 0.9987 221125_WJC_METTL3_EV_vs_WT_F07.08318.08318.3 0.201 Oct-44 K.RAGELTEDEVER[166.11].V sp|P62269|RS18_HUMAN 1 1412.6771 - 96546 8318 3 1412.675258 471.8996 40S ribosomal protein S18 OS=Homo sapiens OX=9606 GN=RPS18 PE=1 SV=3 4.25 1837.9 - 509663 - - - -1.3082 - 1.745 0.284 - 135.9 1 2 0 -0.0018 12 0 0 0 - - - - - 3.249 0.9999 221125_WJC_METTL3_EV_vs_WT_F07.08320.08320.3 1.96E-05 Oct-48 K.IIHEDGYSEEEC[160.03]R.Q sp|P04899|GNAI2_HUMAN 1 1635.6835 1.24 96548 8320 3 1635.681832 546.2351 Guanine nucleotide-binding protein G(i) subunit alpha-2 OS=Homo sapiens OX=9606 GN=GNAI2 PE=1 SV=3 4.25 1838.2 - 341501 - - - -1.0204 - 1.939 0.444 - 171.8 1 2 0 -0.0017 13 0 0 0 5.89E+06 4.73E+06 - - - 5.285 1 221125_WJC_METTL3_EV_vs_WT_F07.08321.08321.2 3.43E-07 18-Dec K.K[136.11]ADNVVNIAR[166.11].Y sp|Q92621|NU205_HUMAN 1 1116.637 1.67 96549 8321 2 1116.636804 559.3258 Nuclear pore complex protein Nup205 OS=Homo sapiens OX=9606 GN=NUP205 PE=1 SV=3 8.75 1838.3 - 201083 - - - -0.1988 - 2.86 0.589 - 511.5 1 2 0 -0.0002 10 0 0 0 1.16E+07 6.96E+06 - - - 6.3244 0.9999 221125_WJC_METTL3_EV_vs_WT_F07.08324.08324.3 0.00253 Nov-40 K.NILNK[136.11]PEVNQK[136.11].L "sp|P52732|KIF11_HUMAN,tr|A0A7I2YQY4|A0A7I2YQY4_HUMAN,tr|A0A7I2V3A9|A0A7I2V3A9_HUMAN,tr|A0A7I2V3V3|A0A7I2V3V3_HUMAN" 4 1311.7481 4.83 96550 8324 3 1311.746745 438.2567 Kinesin-like protein KIF11 OS=Homo sapiens OX=9606 GN=KIF11 PE=1 SV=2 8.59 1838.7 - 3.20E+06 - - - -1.0711 - 2.2 0.417 - 153.3 1 2 0 -0.0014 11 0 0 0 3.52E+09 7.30E+08 - - - 5.4286 0.9999 221125_WJC_METTL3_EV_vs_WT_F07.08327.08327.2 0.00184 13/18 K.KADNVVNIAR.Y sp|Q92621|NU205_HUMAN 1 1098.6146 1.67 96553 8327 2 1098.613511 550.3146 Nuclear pore complex protein Nup205 OS=Homo sapiens OX=9606 GN=NUP205 PE=1 SV=3 8.75 1839 - 723984 - - - -0.9512 - 2.14 0.502 - 641.6 1 2 0 -0.001 10 0 0 0 1.16E+07 6.96E+06 - - - 4.8721 0.9999 221125_WJC_METTL3_EV_vs_WT_F07.08334.08334.3 0.00368 13/48 K.ETGYVVERPSTTK.D "sp|Q9NYF8|BCLF1_HUMAN,tr|E9PKI6|E9PKI6_HUMAN,tr|A0A1W2PQ43|A0A1W2PQ43_HUMAN,tr|E9PK91|E9PK91_HUMAN,tr|E9PK09|E9PK09_HUMAN,tr|E9PQN2|E9PQN2_HUMAN" 6 1465.7413 2.17 96559 8334 3 1465.740013 489.5877 Bcl-2-associated transcription factor 1 OS=Homo sapiens OX=9606 GN=BCLAF1 PE=1 SV=2 6.24 1839.8 - 2.17E+07 - - - -0.8596 - 2.279 0.377 - 172 1 2 0 -0.0013 13 0 0 0 8.04E+09 3.71E+09 - - - 4.9762 0.984 221125_WJC_METTL3_EV_vs_WT_F07.08338.08338.2 0.000577 16-Dec L.LNKPEVNQK.L "sp|P52732|KIF11_HUMAN,tr|A0A7I2YQY4|A0A7I2YQY4_HUMAN,tr|A0A7I2V3A9|A0A7I2V3A9_HUMAN,tr|A0A7I2V3V3|A0A7I2V3V3_HUMAN" 4 1068.5928 5.03 96563 8338 2 1068.591878 535.3037 Kinesin-like protein KIF11 OS=Homo sapiens OX=9606 GN=KIF11 PE=1 SV=2 8.59 1840.1 - 1.60E+06 - - - -0.8235 - 2.188 0.342 - 369 1 1 0 -0.0009 9 0 0 0 2.43E+08 4.82E+07 - - - 3.832 0.9997 221125_WJC_METTL3_EV_vs_WT_F07.08340.08340.2 0.0509 20-Nov K.NILNK[136.11]PEVNQK[136.11].L "sp|P52732|KIF11_HUMAN,tr|A0A7I2YQY4|A0A7I2YQY4_HUMAN,tr|A0A7I2V3A9|A0A7I2V3A9_HUMAN,tr|A0A7I2V3V3|A0A7I2V3V3_HUMAN" 4 1311.7481 4.97 96565 8340 2 1311.747712 656.8814 Kinesin-like protein KIF11 OS=Homo sapiens OX=9606 GN=KIF11 PE=1 SV=2 8.59 1840.4 - 686556 - - - -0.3339 - 2.03 0.333 - 271.8 1 2 0 -0.0004 11 0 0 0 5.50E+08 1.11E+08 - - - 3.4158 0.9997 221125_WJC_METTL3_EV_vs_WT_F07.08342.08342.2 0.0139 22-Sep R.SPSPAHLPDDPK[136.11].V "sp|Q92615|LAR4B_HUMAN,tr|A0A087X183|A0A087X183_HUMAN,tr|H0Y641|H0Y641_HUMAN,tr|H0Y4V9|H0Y4V9_HUMAN" 4 1267.6288 1.51 96567 8342 2 1267.630816 634.8217 La-related protein 4B OS=Homo sapiens OX=9606 GN=LARP4B PE=1 SV=3 5.19 1840.6 - 359400 - - - 1.5777 - 1.949 0.484 - 167 1 2 0 0.002 12 0 0 0 3.99E+07 2.64E+07 - - - 4.371 1 221125_WJC_METTL3_EV_vs_WT_F07.08345.08345.3 1.57E-05 15/48 K.ETGYVVER[166.11]PSTTK[136.11].D "sp|Q9NYF8|BCLF1_HUMAN,tr|E9PKI6|E9PKI6_HUMAN,tr|A0A1W2PQ43|A0A1W2PQ43_HUMAN,tr|E9PK91|E9PK91_HUMAN,tr|E9PK09|E9PK09_HUMAN,tr|E9PQN2|E9PQN2_HUMAN" 6 1483.7637 2.17 96569 8345 3 1483.76359 495.5952 Bcl-2-associated transcription factor 1 OS=Homo sapiens OX=9606 GN=BCLAF1 PE=1 SV=2 6.24 1841 - 3.02E+06 - - - -0.1031 - 2.498 0.48 - 223.1 1 2 0 -0.0002 13 0 0 0 8.03E+09 3.71E+09 - - - 6.3736 0.9998 221125_WJC_METTL3_EV_vs_WT_F07.08347.08347.2 0.0141 20-Nov K.NILNKPEVNQK.L "sp|P52732|KIF11_HUMAN,tr|A0A7I2YQY4|A0A7I2YQY4_HUMAN,tr|A0A7I2V3A9|A0A7I2V3A9_HUMAN,tr|A0A7I2V3V3|A0A7I2V3V3_HUMAN" 4 1295.7197 4.97 96571 8347 2 1295.718392 648.8672 Kinesin-like protein KIF11 OS=Homo sapiens OX=9606 GN=KIF11 PE=1 SV=2 8.59 1841.1 - 6.24E+06 - - - -1.0481 - 2.37 0.406 - 339.3 1 2 0 -0.0014 11 0 0 0 5.50E+08 1.11E+08 - - - 4.3736 0.9378 221125_WJC_METTL3_EV_vs_WT_F07.08349.08349.2 0.00752 16-Aug L.LNK[136.11]PEVNQK[136.11].L "sp|P52732|KIF11_HUMAN,tr|A0A7I2YQY4|A0A7I2YQY4_HUMAN,tr|A0A7I2V3A9|A0A7I2V3A9_HUMAN,tr|A0A7I2V3V3|A0A7I2V3V3_HUMAN" 4 1084.6212 5.03 96573 8349 2 1084.61877 543.3179 Kinesin-like protein KIF11 OS=Homo sapiens OX=9606 GN=KIF11 PE=1 SV=2 8.59 1841.4 - 789058 - - - -2.2017 - 1.463 0.407 - 183.9 1 1 0 -0.0024 9 0 0 0 2.43E+08 4.82E+07 - - - 3.1471 0.9992 221125_WJC_METTL3_EV_vs_WT_F07.08354.08354.3 0.000975 Nov-40 K.TK[136.11]DGVVEITGK[136.11].H "sp|P04792|HSPB1_HUMAN,tr|A0A6Q8PHJ6|A0A6Q8PHJ6_HUMAN,tr|A0A6Q8PFK8|A0A6Q8PFK8_HUMAN" 3 1161.6576 2.05 96576 8354 3 1161.65632 388.2265 Heat shock protein beta-1 OS=Homo sapiens OX=9606 GN=HSPB1 PE=1 SV=2 5.73 1841.9 - 6.07E+06 - - - -1.1045 - 2.251 0.353 - 181.2 1 2 1 -0.0013 11 0 0 0 5.98E+08 2.93E+08 - - - 4.7802 0.9889 221125_WJC_METTL3_EV_vs_WT_F07.08355.08355.2 0.00252 13/20 K.TKDGVVEITGK.H "sp|P04792|HSPB1_HUMAN,tr|A0A6Q8PHJ6|A0A6Q8PHJ6_HUMAN,tr|A0A6Q8PFK8|A0A6Q8PFK8_HUMAN" 3 1145.6292 2.1 96577 8355 2 1145.63385 573.8219 Heat shock protein beta-1 OS=Homo sapiens OX=9606 GN=HSPB1 PE=1 SV=2 5.73 1841.9 - 4.59E+06 - - - 4.0563 - 2.325 0.527 - 368.3 1 2 1 0.0046 11 0 0 0 2.47E+08 1.18E+08 - - - 5.2144 0.9772 221125_WJC_METTL3_EV_vs_WT_F07.08356.08356.2 0.00378 14/20 K.TK[136.11]DGVVEITGK[136.11].H "sp|P04792|HSPB1_HUMAN,tr|A0A6Q8PHJ6|A0A6Q8PHJ6_HUMAN,tr|A0A6Q8PFK8|A0A6Q8PFK8_HUMAN" 3 1161.6576 2.1 96578 8356 2 1161.663324 581.8361 Heat shock protein beta-1 OS=Homo sapiens OX=9606 GN=HSPB1 PE=1 SV=2 5.73 1842 - 2.86E+06 - - - 4.9249 - 2.377 0.492 - 367.1 1 2 1 0.0057 11 0 0 0 2.47E+08 1.18E+08 - - - 5.0154 0.9145 221125_WJC_METTL3_EV_vs_WT_F07.08360.08360.3 2.15 16/40 K.NILNK[136.11]PEVNQK.L "sp|P52732|KIF11_HUMAN,tr|A0A7I2YQY4|A0A7I2YQY4_HUMAN,tr|A0A7I2V3A9|A0A7I2V3A9_HUMAN,tr|A0A7I2V3V3|A0A7I2V3V3_HUMAN" 4 1303.734 - 96581 8360 3 1303.730782 435.5853 Kinesin-like protein KIF11 OS=Homo sapiens OX=9606 GN=KIF11 PE=1 SV=2 8.59 1842.5 - 900472 - - - -2.4299 - 1.66 0.095 - 297.9 1 2 0 -0.0032 11 0 0 0 - - - - - 1.0381 0.9996 221125_WJC_METTL3_EV_vs_WT_F07.08364.08364.3 0.00624 Dec-40 K.TKDGVVEITGK.H "sp|P04792|HSPB1_HUMAN,tr|A0A6Q8PHJ6|A0A6Q8PHJ6_HUMAN,tr|A0A6Q8PFK8|A0A6Q8PFK8_HUMAN" 3 1145.6292 2.05 96583 8364 3 1145.630493 382.8837 Heat shock protein beta-1 OS=Homo sapiens OX=9606 GN=HSPB1 PE=1 SV=2 5.73 1843 - 1.54E+07 - - - 1.126 - 2.152 0.431 - 275.9 1 2 1 0.0013 11 0 0 0 5.98E+08 2.93E+08 - - - 5.5221 0.9676 221125_WJC_METTL3_EV_vs_WT_F07.08366.08366.2 0.217 18-Nov N.ILNKPEVNQK.L "sp|P52732|KIF11_HUMAN,tr|A0A7I2YQY4|A0A7I2YQY4_HUMAN,tr|A0A7I2V3A9|A0A7I2V3A9_HUMAN,tr|A0A7I2V3V3|A0A7I2V3V3_HUMAN" 4 1181.6768 5 96585 8366 2 1181.674816 591.8457 Kinesin-like protein KIF11 OS=Homo sapiens OX=9606 GN=KIF11 PE=1 SV=2 8.59 1843.2 - 873112 - - - -1.6976 - 2.162 0.314 - 378.9 1 1 0 -0.002 10 0 0 0 2.58E+07 5.15E+06 - - - 3.5118 0.9105 221125_WJC_METTL3_EV_vs_WT_F07.08367.08367.3 0.0941 Aug-36 R.AQFEQLK[136.11]DGK[136.11].T "sp|Q15149|PLEC_HUMAN,tr|H0YDN1|H0YDN1_HUMAN" 2 1178.6266 0.91 96586 8367 3 1178.624535 393.8828 Plectin OS=Homo sapiens OX=9606 GN=PLEC PE=1 SV=3 6.11 1843.3 - 526263 - - - -1.7843 - 1.345 0.199 - 100.4 1 2 1 -0.0021 10 0 0 0 1.48E+07 1.62E+07 - - - 1.6237 1 221125_WJC_METTL3_EV_vs_WT_F07.08373.08373.3 2.17E-05 13/56 R.AAHSEGNTTAGLDMR[166.11].E sp|P78371|TCPB_HUMAN 1 1539.6975 0.42 96590 8373 3 1539.69776 514.2398 T-complex protein 1 subunit beta OS=Homo sapiens OX=9606 GN=CCT2 PE=1 SV=4 5.32 1843.9 - 1.15E+06 - - - 0.1533 - 2.479 0.556 - 165.1 1 2 0 0.0002 15 0 0 0 2.70E+07 6.38E+07 - - - 7.1077 0.9983 221125_WJC_METTL3_EV_vs_WT_F07.08379.08379.2 0.00162 16/22 K.LKAEQEALESQR.Q sp|Q5VT06|CE350_HUMAN 1 1400.726 2.41 96594 8379 2 1400.724208 701.3703 Centrosome-associated protein 350 OS=Homo sapiens OX=9606 GN=CEP350 PE=1 SV=1 4.79 1844.6 - 1.77E+06 - - - -1.2486 - 2.552 0.465 - 650.1 1 2 1 -0.0018 12 0 0 0 2.07E+07 8.56E+06 - - - 4.94 0.9998 221125_WJC_METTL3_EV_vs_WT_F07.08381.08381.3 0.0825 Nov-36 K.FHNELNAHIK.L sp|P12270|TPR_HUMAN 1 1221.6255 0.54 96595 8381 3 1221.623194 408.2158 Nucleoprotein TPR OS=Homo sapiens OX=9606 GN=TPR PE=1 SV=3 6.92 1844.8 - 7.31E+06 - - - -1.8508 - 2.071 0.394 - 177.8 1 2 0 -0.0023 10 0 0 0 9.61E+07 1.79E+08 - - - 5.0583 1 221125_WJC_METTL3_EV_vs_WT_F07.08384.08384.3 4.92E-06 16/52 R.NIIHGSDSVESAEK.E sp|P15531|NDKA_HUMAN 1 1484.7107 1.57 96598 8384 3 1484.709745 495.9108 Nucleoside diphosphate kinase A OS=Homo sapiens OX=9606 GN=NME1 PE=1 SV=1 4.65 1845 - 1.19E+06 - - - -0.6439 - 2.739 0.472 - 325.7 1 2 0 -0.001 14 0 0 0 7.44E+08 4.75E+08 - - - 6.4798 0.9955 221125_WJC_METTL3_EV_vs_WT_F07.08385.08385.2 0.000364 16-Sep K.EHVIEALRR.A "sp|P27635|RL10_HUMAN,sp|Q96L21|RL10L_HUMAN,tr|H7C123|H7C123_HUMAN,tr|H7C2C5|H7C2C5_HUMAN,tr|F8W7C6|F8W7C6_HUMAN,tr|X1WI28|X1WI28_HUMAN" 6 1121.6305 0.9 96599 8385 2 1121.627605 561.8225 60S ribosomal protein L10 OS=Homo sapiens OX=9606 GN=RPL10 PE=1 SV=4 6.86 1845.1 - 892104 - - - -2.6176 - 1.824 0.182 - 231.5 1 2 0 -0.0029 9 0 0 0 2.43E+07 2.69E+07 - - - 2.1231 0.8667 221125_WJC_METTL3_EV_vs_WT_F07.08391.08391.3 4.36 Jul-40 K.KLTGGSNWQPK.V "sp|Q13492|PICAL_HUMAN,tr|H0YE97|H0YE97_HUMAN,tr|H0YD48|H0YD48_HUMAN,tr|H0YEY8|H0YEY8_HUMAN,tr|H0YEF7|H0YEF7_HUMAN,tr|H0YCY1|H0YCY1_HUMAN,tr|H0YEH1|H0YEH1_HUMAN" 7 1214.6408 10.36 96603 8391 3 1214.638599 405.8875 Phosphatidylinositol-binding clathrin assembly protein OS=Homo sapiens OX=9606 GN=PICALM PE=1 SV=2 10 1845.8 - 1.64E+06 - - - -1.7882 - 1.207 0.129 - 56.9 1 2 0 -0.0022 11 0 0 0 2.11E+07 2.03E+06 - - - 0.5121 1 221125_WJC_METTL3_EV_vs_WT_F07.08392.08392.3 4.47E-08 13/52 R.NIIHGSDSVESAEK[136.11].E sp|P15531|NDKA_HUMAN 1 1492.7249 1.57 96604 8392 3 1492.723781 498.5822 Nucleoside diphosphate kinase A OS=Homo sapiens OX=9606 GN=NME1 PE=1 SV=1 4.65 1845.8 - 2.69E+06 - - - -0.7503 - 2.613 0.584 - 198.1 1 2 0 -0.0011 14 0 0 0 7.44E+08 4.75E+08 - - - 7.6033 0.9999 221125_WJC_METTL3_EV_vs_WT_F07.08394.08394.3 1.74E-06 Dec-56 K.YYEDK[136.11]PQGGAC[160.03]AGLK[136.11].E "sp|Q86WW8|COA5_HUMAN,tr|B9A057|B9A057_HUMAN" 2 1671.7898 1.68 96606 8394 3 1671.786117 558.2705 Cytochrome c oxidase assembly factor 5 OS=Homo sapiens OX=9606 GN=COA5 PE=1 SV=1 6.06 1846 - 831766 - - - -2.1773 - 2.006 0.553 - 76.3 1 2 0 -0.0036 15 0 0 0 1.17E+07 6.94E+06 - - - 6.5209 0.7993 221125_WJC_METTL3_EV_vs_WT_F07.08396.08396.3 0.496 Sep-44 R.SPSPAHLPDDPK[136.11].V "sp|Q92615|LAR4B_HUMAN,tr|A0A087X183|A0A087X183_HUMAN,tr|H0Y641|H0Y641_HUMAN,tr|H0Y4V9|H0Y4V9_HUMAN" 4 1267.6288 1.43 96607 8396 3 1267.627463 423.5502 La-related protein 4B OS=Homo sapiens OX=9606 GN=LARP4B PE=1 SV=3 5.19 1846.3 - 6.14E+06 - - - -1.0673 - 1.348 0.059 - 95.6 1 2 0 -0.0014 12 0 0 0 3.02E+08 2.11E+08 - - - 0.0252 0.9999 221125_WJC_METTL3_EV_vs_WT_F07.08398.08398.3 3.95E-06 13/56 R.AAHSEGNTTAGLDMR.E sp|P78371|TCPB_HUMAN 1 1529.6893 0.42 96608 8398 3 1529.685828 510.9037 T-complex protein 1 subunit beta OS=Homo sapiens OX=9606 GN=CCT2 PE=1 SV=4 5.32 1846.5 - 1.92E+06 - - - -2.2397 - 2.24 0.528 - 214.4 1 2 0 -0.0034 15 0 0 0 2.70E+07 6.39E+07 - - - 6.5301 0.7827 221125_WJC_METTL3_EV_vs_WT_F07.08399.08399.2 0.442 20-Nov K.QHGVNVSVNAS.A "sp|Q14157|UBP2L_HUMAN,tr|F8W726|F8W726_HUMAN,tr|H7C2T8|H7C2T8_HUMAN,tr|H0Y5H6|H0Y5H6_HUMAN" 4 1110.5418 - 96609 8399 2 1110.540195 556.2782 Ubiquitin-associated protein 2-like OS=Homo sapiens OX=9606 GN=UBAP2L PE=1 SV=2 6.74 1846.6 - 1.19E+06 - - - -1.4317 - 1.289 0.234 - 216.1 1 1 0 -0.0016 11 0 0 0 - - - - - 1.4556 0.9998 221125_WJC_METTL3_EV_vs_WT_F07.08401.08401.3 4.43E-07 13/52 K.IVADK[136.11]DYSVTANSK[136.11].L "sp|P07195|LDHB_HUMAN,tr|A8MW50|A8MW50_HUMAN,tr|A0A3B3IS95|A0A3B3IS95_HUMAN,tr|C9J7H8|C9J7H8_HUMAN,tr|F5H793|F5H793_HUMAN,tr|A0A5F9ZHM4|A0A5F9ZHM4_HUMAN" 6 1525.7959 0.71 96611 8401 3 1525.792159 509.6059 L-lactate dehydrogenase B chain OS=Homo sapiens OX=9606 GN=LDHB PE=1 SV=2 5.96 1846.7 - 2.11E+06 - - - -2.444 - 2.955 0.499 - 224.8 1 2 1 -0.0037 14 0 0 0 9.70E+07 1.36E+08 - - - 6.9818 1 221125_WJC_METTL3_EV_vs_WT_F07.08402.08402.2 1.47E-06 16/24 L.ATQVEGQATNLQR.L "sp|P14923|PLAK_HUMAN,tr|C9JKY1|C9JKY1_HUMAN,tr|C9JK18|C9JK18_HUMAN,tr|C9JTX4|C9JTX4_HUMAN,tr|C9J826|C9J826_HUMAN" 5 1414.7165 2.31 96612 8402 2 1414.714394 708.3655 Junction plakoglobin OS=Homo sapiens OX=9606 GN=JUP PE=1 SV=3 6.05 1846.9 - 1.24E+06 - - - -1.4568 - 3.071 0.578 - 927.3 1 1 0 -0.0021 13 0 0 0 1.47E+07 6.36E+06 - - - 6.1891 0.9868 221125_WJC_METTL3_EV_vs_WT_F07.08404.08404.2 2.33E-05 16-Oct N.TC[160.03]FHMDTC[160.03]K[136.11].Y "sp|Q86U44|MTA70_HUMAN,tr|H0YFV6|H0YFV6_HUMAN" 2 1206.4711 0.001 96614 8404 2 1206.468375 604.2428 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 6.4 1847.1 - 579050 - - - -2.2877 - 2.08 0.608 - 428.6 1 1 0 -0.0028 9 0 0 0 0.00E+00 1.15E+07 - - - 5.6496 0.9984 221125_WJC_METTL3_EV_vs_WT_F07.08405.08405.2 0.0327 16-May K.RAQAWC[160.03]YSK.N "sp|P51149|RAB7A_HUMAN,tr|C9J592|C9J592_HUMAN,tr|C9J4V0|C9J4V0_HUMAN,tr|A0A6Q8PH84|A0A6Q8PH84_HUMAN,tr|C9J8S3|C9J8S3_HUMAN,tr|A0A6Q8PGE6|A0A6Q8PGE6_HUMAN,tr|A0A6Q8PG52|A0A6Q8PG52_HUMAN" 7 1168.5448 0.66 96615 8405 2 1168.544479 585.2797 Ras-related protein Rab-7a OS=Homo sapiens OX=9606 GN=RAB7A PE=1 SV=1 9.31 1847.3 - 494420 - - - -0.2422 - 1.293 0.295 - 92.9 1 2 0 -0.0003 9 0 0 0 2.85E+06 4.29E+06 - - - 1.9632 1 221125_WJC_METTL3_EV_vs_WT_F07.08410.08410.2 7.10E-07 19/26 R.NIIHGSDSVESAEK.E sp|P15531|NDKA_HUMAN 1 1484.7107 1.59 96618 8410 2 1484.708637 743.3626 Nucleoside diphosphate kinase A OS=Homo sapiens OX=9606 GN=NME1 PE=1 SV=1 4.65 1847.8 - 2.92E+06 - - - -1.3902 - 3.53 0.674 - 1152.1 1 2 0 -0.0021 14 0 0 0 1.22E+08 7.70E+07 - - - 7.1837 0.9998 221125_WJC_METTL3_EV_vs_WT_F07.08411.08411.3 9.11E-06 14/52 K.IVADKDYSVTANSK.L "sp|P07195|LDHB_HUMAN,tr|A8MW50|A8MW50_HUMAN,tr|A0A3B3IS95|A0A3B3IS95_HUMAN,tr|C9J7H8|C9J7H8_HUMAN,tr|F5H793|F5H793_HUMAN,tr|A0A5F9ZHM4|A0A5F9ZHM4_HUMAN" 6 1509.7675 0.71 96619 8411 3 1509.768815 504.2631 L-lactate dehydrogenase B chain OS=Homo sapiens OX=9606 GN=LDHB PE=1 SV=2 5.96 1847.9 - 2.38E+06 - - - 0.8789 - 2.553 0.443 - 233.8 1 2 1 0.0013 14 0 0 0 9.70E+07 1.36E+08 - - - 5.9695 0.9999 221125_WJC_METTL3_EV_vs_WT_F07.08412.08412.2 2.22E-05 13/22 R.FSNSSSSNEFSK.C sp|Q5D862|FILA2_HUMAN 1 1319.563 999 96620 8412 2 1319.562158 660.7888 Filaggrin-2 OS=Homo sapiens OX=9606 GN=FLG2 PE=1 SV=1 6 1848 - 1.94E+06 - - - -0.6184 - 2.527 0.441 - 419.9 1 2 0 -0.0008 12 0 0 0 2.40E+08 0.00E+00 - - - 4.7372 0.9992 221125_WJC_METTL3_EV_vs_WT_F07.08413.08413.3 0.014 Sep-40 K.KEETQPPVALK.K sp|Q8NC51|PAIRB_HUMAN 1 1238.6871 0.92 96621 8413 3 1238.687669 413.903 Plasminogen activator inhibitor 1 RNA-binding protein OS=Homo sapiens OX=9606 GN=SERBP1 PE=1 SV=2 6.14 1848.1 - 1.11E+06 - - - 0.4973 - 1.702 0.307 - 95.3 1 2 0 0.0006 11 0 0 0 2.73E+07 2.99E+07 - - - 3.4733 0.778 221125_WJC_METTL3_EV_vs_WT_F07.08414.08414.2 0.945 22-Aug R.TGQK[136.11]VNPGNTGK.L sp|Q9NQV7|PRDM9_HUMAN 1 1207.64 - 96622 8414 2 1207.640986 604.8273 Histone-lysine N-methyltransferase PRDM9 OS=Homo sapiens OX=9606 GN=PRDM9 PE=1 SV=2 10 1848.2 - 637646 - - - 0.7759 - 1.211 0.098 - 110.7 2 2 1 0.0009 12 0 0 0 - - - - - 0.1338 1 221125_WJC_METTL3_EV_vs_WT_F07.08417.08417.2 3.98E-09 18/26 R.NIIHGSDSVESAEK[136.11].E sp|P15531|NDKA_HUMAN 1 1492.7249 1.58 96623 8417 2 1492.723893 747.3697 Nucleoside diphosphate kinase A OS=Homo sapiens OX=9606 GN=NME1 PE=1 SV=1 4.65 1848.6 - 4.14E+06 - - - -0.6753 - 3.399 0.58 - 887.4 1 2 0 -0.001 14 0 0 0 1.22E+08 7.70E+07 - - - 6.3948 0.9999 221125_WJC_METTL3_EV_vs_WT_F07.08419.08419.2 2.92E-05 16/20 R.K[136.11]ITIGQAPTEK[136.11].G "sp|P11586|C1TC_HUMAN,tr|F5H2F4|F5H2F4_HUMAN,tr|V9GZ78|V9GZ78_HUMAN,tr|V9GYY3|V9GYY3_HUMAN,tr|A0A494C1T2|A0A494C1T2_HUMAN" 5 1200.7049 1.74 96625 8419 2 1200.70442 601.3597 "C-1-tetrahydrofolate synthase, cytoplasmic OS=Homo sapiens OX=9606 GN=MTHFD1 PE=1 SV=4" 8.59 1848.8 - 1.54E+06 - - - -0.3898 - 2.542 0.463 - 681.1 1 2 0 -0.0005 11 0 0 0 4.44E+07 2.55E+07 - - - 4.9844 1 221125_WJC_METTL3_EV_vs_WT_F07.08420.08420.3 0.000124 15/56 K.YYEDKPQGGAC[160.03]AGLK.E "sp|Q86WW8|COA5_HUMAN,tr|B9A057|B9A057_HUMAN" 2 1655.7614 1.68 96626 8420 3 1655.761299 552.9277 Cytochrome c oxidase assembly factor 5 OS=Homo sapiens OX=9606 GN=COA5 PE=1 SV=1 6.06 1848.9 - 964425 - - - -0.035 - 2.171 0.495 - 149.9 1 2 0 -0.0001 15 0 0 0 1.17E+07 6.94E+06 - - - 6.0815 1 221125_WJC_METTL3_EV_vs_WT_F07.08421.08421.2 1.41E-05 17/26 K.IVADK[136.11]DYSVTANSK[136.11].L "sp|P07195|LDHB_HUMAN,tr|A8MW50|A8MW50_HUMAN,tr|A0A3B3IS95|A0A3B3IS95_HUMAN,tr|C9J7H8|C9J7H8_HUMAN,tr|F5H793|F5H793_HUMAN,tr|A0A5F9ZHM4|A0A5F9ZHM4_HUMAN" 6 1525.7959 0.58 96627 8421 2 1525.793513 763.9052 L-lactate dehydrogenase B chain OS=Homo sapiens OX=9606 GN=LDHB PE=1 SV=2 5.96 1849 - 829281 - - - -1.5566 - 3.303 0.591 - 935.4 1 2 1 -0.0024 14 0 0 0 7.86E+06 1.35E+07 - - - 6.4037 1 221125_WJC_METTL3_EV_vs_WT_F07.08423.08423.2 2.30E-09 16/26 K.IVADKDYSVTANSK.L "sp|P07195|LDHB_HUMAN,tr|A8MW50|A8MW50_HUMAN,tr|A0A3B3IS95|A0A3B3IS95_HUMAN,tr|C9J7H8|C9J7H8_HUMAN,tr|F5H793|F5H793_HUMAN,tr|A0A5F9ZHM4|A0A5F9ZHM4_HUMAN" 6 1509.7675 0.58 96629 8423 2 1509.766429 755.891 L-lactate dehydrogenase B chain OS=Homo sapiens OX=9606 GN=LDHB PE=1 SV=2 5.96 1849.2 - 589877 - - - -0.7014 - 3.112 0.665 - 866.4 1 2 1 -0.0011 14 0 0 0 7.86E+06 1.35E+07 - - - 6.8012 1 221125_WJC_METTL3_EV_vs_WT_F07.08425.08425.2 1.37E-07 13/30 R.SGGGGGGGLGSGGSIR.S sp|P35527|K1C9_HUMAN 1 1231.5905 999 96631 8425 2 1231.588494 616.8025 "Keratin, type I cytoskeletal 9 OS=Homo sapiens OX=9606 GN=KRT9 PE=1 SV=3" 9.47 1849.5 - 493092 - - - -1.6499 - 2.677 0.604 - 424.4 1 2 0 -0.002 16 0 0 0 1.18E+07 0.00E+00 - - - 5.9224 0.8045 221125_WJC_METTL3_EV_vs_WT_F07.08426.08426.2 0.228 18-May K.FHNELNAHIK.L sp|P12270|TPR_HUMAN 1 1221.6255 1.1 96632 8426 2 1221.623509 611.82 Nucleoprotein TPR OS=Homo sapiens OX=9606 GN=TPR PE=1 SV=3 6.92 1849.6 - 337424 - - - -1.593 - 0.999 0.014 - 59.5 3 2 0 -0.0019 10 0 0 0 4.69E+06 4.28E+06 - - - -1.0721 0.9999 221125_WJC_METTL3_EV_vs_WT_F07.08432.08432.2 9.66E-05 13/20 R.KITIGQAPTEK.G "sp|P11586|C1TC_HUMAN,tr|F5H2F4|F5H2F4_HUMAN,tr|V9GZ78|V9GZ78_HUMAN,tr|V9GYY3|V9GYY3_HUMAN,tr|A0A494C1T2|A0A494C1T2_HUMAN" 5 1184.6765 1.74 96636 8432 2 1184.67531 593.3455 "C-1-tetrahydrofolate synthase, cytoplasmic OS=Homo sapiens OX=9606 GN=MTHFD1 PE=1 SV=4" 8.59 1850.4 - 2.89E+06 - - - -0.9944 - 2.422 0.511 - 456.6 1 2 0 -0.0012 11 0 0 0 4.44E+07 2.55E+07 - - - 5.2079 0.9999 221125_WJC_METTL3_EV_vs_WT_F07.08434.08434.3 9.76E-05 20/48 R.ALQSLAC[160.03]GKPTQR.V "sp|Q13618|CUL3_HUMAN,tr|A0A087WTG3|A0A087WTG3_HUMAN" 2 1428.7507 1.71 96638 8434 3 1428.749083 477.2575 Cullin-3 OS=Homo sapiens OX=9606 GN=CUL3 PE=1 SV=2 9.51 1850.5 - 1.63E+06 - - - -1.1549 - 2.92 0.403 - 668.2 1 2 0 -0.0016 13 0 0 0 2.32E+07 1.36E+07 - - - 5.938 0.9999 221125_WJC_METTL3_EV_vs_WT_F07.08438.08438.3 0.00292 21/48 R.ALQSLAC[160.03]GK[136.11]PTQR[166.11].V "sp|Q13618|CUL3_HUMAN,tr|A0A087WTG3|A0A087WTG3_HUMAN" 2 1446.7732 1.71 96642 8438 3 1446.772167 483.265 Cullin-3 OS=Homo sapiens OX=9606 GN=CUL3 PE=1 SV=2 9.51 1850.8 - 897894 - - - -0.7161 - 2.584 0.336 - 752.8 1 2 0 -0.001 13 0 0 0 2.32E+07 1.36E+07 - - - 4.8597 0.9991 221125_WJC_METTL3_EV_vs_WT_F07.08445.08445.3 0.000439 Dec-52 K.IVADKDYSVTANSK[136.11].L "sp|P07195|LDHB_HUMAN,tr|A8MW50|A8MW50_HUMAN,tr|A0A3B3IS95|A0A3B3IS95_HUMAN,tr|C9J7H8|C9J7H8_HUMAN,tr|F5H793|F5H793_HUMAN,tr|A0A5F9ZHM4|A0A5F9ZHM4_HUMAN" 6 1517.7817 - 96647 8445 3 1517.781422 506.9345 L-lactate dehydrogenase B chain OS=Homo sapiens OX=9606 GN=LDHB PE=1 SV=2 5.96 1851.7 - 518902 - - - -0.1753 - 2.074 0.37 - 156 1 2 1 -0.0003 14 0 0 0 - - - - - 4.6037 0.9725 221125_WJC_METTL3_EV_vs_WT_F07.08448.08448.2 0.042 18-Nov K.NKELEIAQDR.N sp|P12270|TPR_HUMAN 1 1214.6255 3.4 96650 8448 2 1214.624052 608.32 Nucleoprotein TPR OS=Homo sapiens OX=9606 GN=TPR PE=1 SV=3 4.68 1852.1 - 386279 - - - -1.2045 - 1.965 0.122 - 564.4 1 2 1 -0.0015 10 0 0 0 2.39E+07 7.03E+06 - - - 1.8271 0.9788 221125_WJC_METTL3_EV_vs_WT_F07.08449.08449.2 0.0877 18-Aug K.LLEQYK[136.11]EESK[136.11].K "sp|Q00839|HNRPU_HUMAN,tr|A0A1W2PQL0|A0A1W2PQL0_HUMAN,tr|A0A1W2PPL4|A0A1W2PPL4_HUMAN,tr|Q5RI18|Q5RI18_HUMAN,tr|A0A1W2PP35|A0A1W2PP35_HUMAN,tr|A0A1W2PPS1|A0A1W2PPS1_HUMAN,tr|A0A1W2PPH7|A0A1W2PPH7_HUMAN,tr|A0A1W2PQD4|A0A1W2PQD4_HUMAN,tr|A0A1W2PP34|A0A1W2PP34_HUMAN,tr|A0A1X7SBS1|A0A1X7SBS1_HUMAN" 10 1281.6787 0.81 96651 8449 2 1281.679663 641.8466 Heterogeneous nuclear ribonucleoprotein U OS=Homo sapiens OX=9606 GN=HNRNPU PE=1 SV=6 4.79 1852.2 - 219255 - - - 0.7256 - 1.495 0.242 - 214.8 1 2 1 0.0009 10 0 0 0 4.50E+06 5.56E+06 - - - 1.9506 0.9965 221125_WJC_METTL3_EV_vs_WT_F07.08452.08452.3 0.0158 Nov-32 K.EHVIEALR[166.11]R[166.11].A "sp|P27635|RL10_HUMAN,sp|Q96L21|RL10L_HUMAN,tr|H7C123|H7C123_HUMAN,tr|H7C2C5|H7C2C5_HUMAN,tr|F8W7C6|F8W7C6_HUMAN,tr|X1WI28|X1WI28_HUMAN" 6 1141.6471 0.001 96652 8452 3 1141.646877 381.5563 60S ribosomal protein L10 OS=Homo sapiens OX=9606 GN=RPL10 PE=1 SV=4 6.86 1852.6 - 6.61E+06 - - - -0.1787 - 1.659 0.215 - 174.4 1 2 0 -0.0002 9 0 0 0 0.00E+00 1.96E+08 - - - 2.4626 0.9997 221125_WJC_METTL3_EV_vs_WT_F07.08453.08453.2 5.24E-05 26-Oct R.EQLQTEQDAPAATR.Q "sp|Q96K19|RN170_HUMAN,tr|E9PP55|E9PP55_HUMAN" 2 1556.7431 5.45 96653 8453 2 1556.746325 779.3788 E3 ubiquitin-protein ligase RNF170 OS=Homo sapiens OX=9606 GN=RNF170 PE=1 SV=2 4.14 1852.8 - 480548 - - - 2.0948 - 1.979 0.535 - 226.6 1 2 0 0.0033 14 0 0 0 3.05E+06 5.60E+05 - - - 4.7044 0.9998 221125_WJC_METTL3_EV_vs_WT_F07.08455.08455.3 0.0121 14/44 R.QLVSEGNIHADK.L sp|O15020|SPTN2_HUMAN 1 1309.6626 0.84 96655 8455 3 1309.664024 437.5615 "Spectrin beta chain, non-erythrocytic 2 OS=Homo sapiens OX=9606 GN=SPTBN2 PE=1 SV=3" 5.32 1853 - 671455 - - - 1.0652 - 2.416 0.329 - 297.5 1 2 0 0.0014 12 0 0 0 7.33E+06 8.71E+06 - - - 4.6527 0.9999 221125_WJC_METTL3_EV_vs_WT_F07.08457.08457.2 0.000128 20-Dec K.KEETQPPVALK.K sp|Q8NC51|PAIRB_HUMAN 1 1238.6871 0.65 96657 8457 2 1238.685646 620.3508 Plasminogen activator inhibitor 1 RNA-binding protein OS=Homo sapiens OX=9606 GN=SERBP1 PE=1 SV=2 6.14 1853.3 - 378673 - - - -1.1359 - 2.689 0.516 - 440 1 2 0 -0.0014 11 0 0 0 4.34E+06 6.68E+06 - - - 5.5277 0.9998 221125_WJC_METTL3_EV_vs_WT_F07.08459.08459.2 0.000225 22-Aug R.FEPPQSDSDGQR.R "sp|O15042|SR140_HUMAN,tr|E7EW00|E7EW00_HUMAN,tr|E7ET15|E7ET15_HUMAN,tr|H0Y8D9|H0Y8D9_HUMAN" 4 1361.5848 1.49 96659 8459 2 1361.583768 681.7997 U2 snRNP-associated SURP motif-containing protein OS=Homo sapiens OX=9606 GN=U2SURP PE=1 SV=2 4.03 1853.5 - 249913 - - - -0.7374 - 1.524 0.551 - 99 1 2 0 -0.001 12 0 0 0 5.02E+06 3.36E+06 - - - 4.219 0.9825 221125_WJC_METTL3_EV_vs_WT_F07.08462.08462.2 2.84E-05 28-Sep R.GDVTAEEAAGASPAK[136.11].A sp|P49006|MRP_HUMAN 1 1380.6612 0.25 96662 8462 2 1380.651058 691.3379 MARCKS-related protein OS=Homo sapiens OX=9606 GN=MARCKSL1 PE=1 SV=2 4.14 1853.9 - 165239 - - - -7.3733 - 1.831 0.494 - 149.4 1 2 0 -0.0102 15 0 0 0 6.87E+05 2.78E+06 - - - 4.1736 0.9922 221125_WJC_METTL3_EV_vs_WT_F07.08465.08465.3 0.0258 Sep-36 K.LLEQYK[136.11]EESK[136.11].K "sp|Q00839|HNRPU_HUMAN,tr|A0A1W2PQL0|A0A1W2PQL0_HUMAN,tr|A0A1W2PPL4|A0A1W2PPL4_HUMAN,tr|Q5RI18|Q5RI18_HUMAN,tr|A0A1W2PP35|A0A1W2PP35_HUMAN,tr|A0A1W2PPS1|A0A1W2PPS1_HUMAN,tr|A0A1W2PPH7|A0A1W2PPH7_HUMAN,tr|A0A1W2PQD4|A0A1W2PQD4_HUMAN,tr|A0A1W2PP34|A0A1W2PP34_HUMAN,tr|A0A1X7SBS1|A0A1X7SBS1_HUMAN" 10 1281.6787 0.82 96663 8465 3 1281.679623 428.2335 Heterogeneous nuclear ribonucleoprotein U OS=Homo sapiens OX=9606 GN=HNRNPU PE=1 SV=6 4.79 1854.3 - 3.12E+06 - - - 0.6944 - 1.93 0.222 - 134.9 1 2 1 0.0009 10 0 0 0 2.83E+07 3.45E+07 - - - 2.9351 0.9997 221125_WJC_METTL3_EV_vs_WT_F07.08466.08466.2 0.000284 18-Oct R.DSYESYGNSR.S "sp|Q96E39|RMXL1_HUMAN,sp|P38159|RBMX_HUMAN,tr|H3BUY5|H3BUY5_HUMAN" 3 1176.4683 1.49 96664 8466 2 1176.469094 589.2414 "RNA binding motif protein, X-linked-like-1 OS=Homo sapiens OX=9606 GN=RBMXL1 PE=1 SV=1" 4.37 1854.4 - 2.39E+06 - - - 0.6358 - 1.714 0.461 - 266.5 1 2 0 0.0007 10 0 0 0 2.70E+08 1.81E+08 - - - 3.9497 0.9999 221125_WJC_METTL3_EV_vs_WT_F07.08467.08467.2 4.47E-05 18-Sep R.DSYESYGNSR[166.11].S "sp|Q96E39|RMXL1_HUMAN,sp|P38159|RBMX_HUMAN,tr|H3BUY5|H3BUY5_HUMAN" 3 1186.4766 1.49 96665 8467 2 1186.476631 594.2456 "RNA binding motif protein, X-linked-like-1 OS=Homo sapiens OX=9606 GN=RBMXL1 PE=1 SV=1" 4.37 1854.4 - 2.22E+06 - - - 0.0126 - 1.476 0.592 - 178.4 1 2 0 0 10 0 0 0 2.70E+08 1.81E+08 - - - 4.5003 1 221125_WJC_METTL3_EV_vs_WT_F07.08469.08469.2 1.80E-07 20-Nov Q.SSSYGQQSSFR[166.11].Q "sp|Q01844|EWS_HUMAN,tr|B0QYJ7|B0QYJ7_HUMAN,tr|B0QYK0|B0QYK0_HUMAN,tr|F8WC90|F8WC90_HUMAN" 4 1242.5504 0.58 96667 8469 2 1242.550043 622.2825 RNA-binding protein EWS OS=Homo sapiens OX=9606 GN=EWSR1 PE=1 SV=1 8.46 1854.7 - 613152 - - - -0.3267 - 2.236 0.643 - 497.2 1 1 0 -0.0004 11 0 0 0 6.68E+06 1.16E+07 - - - 5.9669 0.9999 221125_WJC_METTL3_EV_vs_WT_F07.08471.08471.3 0.00477 Sep-48 K.MMNGGHYTYSENR.V "sp|Q99497|PARK7_HUMAN,tr|K7ELW0|K7ELW0_HUMAN" 2 1558.6293 1.88 96669 8471 3 1558.627395 520.5504 Parkinson disease protein 7 OS=Homo sapiens OX=9606 GN=PARK7 PE=1 SV=2 6.5 1854.9 - 477692 - - - -1.2203 - 1.919 0.447 - 86.1 1 2 0 -0.0019 13 0 0 0 2.47E+07 1.32E+07 - - - 5.2903 0.9984 221125_WJC_METTL3_EV_vs_WT_F07.08474.08474.2 4.74E-05 18-Nov K.LLEQYKEESK.K "sp|Q00839|HNRPU_HUMAN,tr|A0A1W2PQL0|A0A1W2PQL0_HUMAN,tr|A0A1W2PPL4|A0A1W2PPL4_HUMAN,tr|Q5RI18|Q5RI18_HUMAN,tr|A0A1W2PP35|A0A1W2PP35_HUMAN,tr|A0A1W2PPS1|A0A1W2PPS1_HUMAN,tr|A0A1W2PPH7|A0A1W2PPH7_HUMAN,tr|A0A1W2PQD4|A0A1W2PQD4_HUMAN,tr|A0A1W2PP34|A0A1W2PP34_HUMAN,tr|A0A1X7SBS1|A0A1X7SBS1_HUMAN" 10 1265.6503 0.81 96672 8474 2 1265.651213 633.8324 Heterogeneous nuclear ribonucleoprotein U OS=Homo sapiens OX=9606 GN=HNRNPU PE=1 SV=6 4.79 1855.3 - 330301 - - - 0.6953 - 2.366 0.458 - 457.3 1 2 1 0.0009 10 0 0 0 4.50E+06 5.56E+06 - - - 4.8274 0.7859 221125_WJC_METTL3_EV_vs_WT_F07.08475.08475.2 0.073 16-Aug R.EHVELLR[166.11]AR[166.11].R sp|Q9H3N8|HRH4_HUMAN 1 1141.6471 0.9 96673 8475 2 1141.648033 571.8308 Histamine H4 receptor OS=Homo sapiens OX=9606 GN=HRH4 PE=1 SV=2 6.86 1855.4 - 315100 - - - 0.8339 - 1.482 0 - 128.9 1 2 1 0.001 9 0 0 0 2.43E+07 2.69E+07 - - - 0.1788 0.9999 221125_WJC_METTL3_EV_vs_WT_F07.08476.08476.3 4.64E-05 Nov-44 R.AEMYDDVHSDGR.Y "sp|Q8IX01|SUGP2_HUMAN,tr|M0R216|M0R216_HUMAN,tr|M0R065|M0R065_HUMAN,tr|M0R2Z9|M0R2Z9_HUMAN,tr|M0R3F6|M0R3F6_HUMAN" 5 1393.5568 0.35 96674 8476 3 1393.552669 465.5262 SURP and G-patch domain-containing protein 2 OS=Homo sapiens OX=9606 GN=SUGP2 PE=1 SV=2 4.22 1855.6 - 410330 - - - -2.9952 - 2.002 0.513 - 127.2 1 2 0 -0.0042 12 0 0 0 7.56E+06 2.18E+07 - - - 6.1824 0.8044 221125_WJC_METTL3_EV_vs_WT_F07.08477.08477.2 0.0046 16-Sep L.LEQYKEESK.K "sp|Q00839|HNRPU_HUMAN,tr|A0A1W2PQL0|A0A1W2PQL0_HUMAN,tr|A0A1W2PPL4|A0A1W2PPL4_HUMAN,tr|Q5RI18|Q5RI18_HUMAN,tr|A0A1W2PP35|A0A1W2PP35_HUMAN,tr|A0A1W2PPS1|A0A1W2PPS1_HUMAN,tr|A0A1W2PPH7|A0A1W2PPH7_HUMAN,tr|A0A1W2PQD4|A0A1W2PQD4_HUMAN,tr|A0A1W2PP34|A0A1W2PP34_HUMAN,tr|A0A1X7SBS1|A0A1X7SBS1_HUMAN" 10 1152.5663 -1 96675 8477 2 1152.56582 577.2904 Heterogeneous nuclear ribonucleoprotein U OS=Homo sapiens OX=9606 GN=HNRNPU PE=1 SV=6 4.79 1855.7 - 159546 - - - -0.3896 - 1.596 0.404 - 290.2 1 1 1 -0.0004 9 0 0 0 0.00E+00 0.00E+00 - - - 3.3773 0.9993 221125_WJC_METTL3_EV_vs_WT_F07.08481.08481.3 0.00045 Oct-36 K.LLEQYKEESK.K "sp|Q00839|HNRPU_HUMAN,tr|A0A1W2PQL0|A0A1W2PQL0_HUMAN,tr|A0A1W2PPL4|A0A1W2PPL4_HUMAN,tr|Q5RI18|Q5RI18_HUMAN,tr|A0A1W2PP35|A0A1W2PP35_HUMAN,tr|A0A1W2PPS1|A0A1W2PPS1_HUMAN,tr|A0A1W2PPH7|A0A1W2PPH7_HUMAN,tr|A0A1W2PQD4|A0A1W2PQD4_HUMAN,tr|A0A1W2PP34|A0A1W2PP34_HUMAN,tr|A0A1X7SBS1|A0A1X7SBS1_HUMAN" 10 1265.6503 0.81 96677 8481 3 1265.650635 422.8907 Heterogeneous nuclear ribonucleoprotein U OS=Homo sapiens OX=9606 GN=HNRNPU PE=1 SV=6 4.79 1856.2 - 4.84E+06 - - - 0.2386 - 1.947 0.384 - 206.2 1 2 1 0.0003 10 0 0 0 2.86E+07 3.54E+07 - - - 4.767 0.9999 221125_WJC_METTL3_EV_vs_WT_F07.08482.08482.3 0.00131 Dec-36 K.RLEIEHSVPK.K sp|Q9NZI8|IF2B1_HUMAN 1 1206.6721 1.97 96678 8482 3 1206.67318 403.2313 Insulin-like growth factor 2 mRNA-binding protein 1 OS=Homo sapiens OX=9606 GN=IGF2BP1 PE=1 SV=2 6.76 1856.3 - 3.15E+06 - - - 0.9191 - 2.12 0.436 - 275.2 1 2 0 0.0011 10 0 0 0 6.21E+07 3.14E+07 - - - 5.5951 0.9999 221125_WJC_METTL3_EV_vs_WT_F07.08484.08484.2 9.70E-08 16-Oct R.MHVQLSTSR.L "sp|Q9BWF3|RBM4_HUMAN,sp|Q9BQ04|RBM4B_HUMAN,tr|E9PB51|E9PB51_HUMAN" 3 1057.5339 1.18 96680 8484 2 1057.535182 529.7742 RNA-binding protein 4 OS=Homo sapiens OX=9606 GN=RBM4 PE=1 SV=1 9.52 1856.4 - 1.94E+06 - - - 1.2472 - 1.928 0.605 - 432.2 1 2 0 0.0013 9 0 0 0 1.58E+07 1.34E+07 - - - 5.4084 1 221125_WJC_METTL3_EV_vs_WT_F07.08485.08485.3 1.54E-05 Dec-32 K.NQLC[160.03]EIPKR.M sp|Q9H9A6|LRC40_HUMAN 1 1156.6023 2.48 96681 8485 3 1156.602558 386.5414 Leucine-rich repeat-containing protein 40 OS=Homo sapiens OX=9606 GN=LRRC40 PE=1 SV=1 8.22 1856.5 - 1.21E+06 - - - 0.243 - 2.348 0.455 - 286 1 2 0 0.0003 9 0 0 0 1.33E+07 5.37E+06 - - - 6.1852 1 221125_WJC_METTL3_EV_vs_WT_F07.08490.08490.3 4.78E-07 14/48 K.MMNGGHYTYSENR[166.11].V "sp|Q99497|PARK7_HUMAN,tr|K7ELW0|K7ELW0_HUMAN" 2 1568.6376 1.88 96686 8490 3 1568.638743 523.8865 Parkinson disease protein 7 OS=Homo sapiens OX=9606 GN=PARK7 PE=1 SV=2 6.5 1856.9 - 928648 - - - 0.7497 - 2.798 0.579 - 283.7 1 2 0 0.0012 13 0 0 0 2.47E+07 1.32E+07 - - - 7.7846 0.9822 221125_WJC_METTL3_EV_vs_WT_F07.08491.08491.2 3.57E-06 20-Nov Q.SSSYGQQSSFR.Q "sp|Q01844|EWS_HUMAN,tr|B0QYJ7|B0QYJ7_HUMAN,tr|B0QYK0|B0QYK0_HUMAN,tr|F8WC90|F8WC90_HUMAN" 4 1232.5422 0.58 96687 8491 2 1232.545276 617.2784 RNA-binding protein EWS OS=Homo sapiens OX=9606 GN=EWSR1 PE=1 SV=1 8.46 1857 - 761202 - - - 2.5127 - 2.169 0.578 - 507.7 1 1 0 0.0031 11 0 0 0 6.68E+06 1.16E+07 - - - 5.4037 0.9999 221125_WJC_METTL3_EV_vs_WT_F07.08493.08493.3 0.00136 14/32 K.NQLC[160.03]EIPK[136.11]R[166.11].M sp|Q9H9A6|LRC40_HUMAN 1 1174.6247 2.94 96689 8493 3 1174.625824 392.5489 Leucine-rich repeat-containing protein 40 OS=Homo sapiens OX=9606 GN=LRRC40 PE=1 SV=1 8.22 1857.3 - 559338 - - - 0.9169 - 2.214 0.417 - 361.3 1 2 0 0.0011 9 0 0 0 1.34E+07 4.56E+06 - - - 5.5842 0.9999 221125_WJC_METTL3_EV_vs_WT_F07.08494.08494.2 0.0387 22-Dec R.SAEYGSSLQSSR.S sp|Q6KB66|K2C80_HUMAN 1 1270.579 999 96690 8494 2 1270.578667 636.2968 "Keratin, type II cytoskeletal 80 OS=Homo sapiens OX=9606 GN=KRT80 PE=1 SV=2" 5.72 1857.4 - 331211 - - - -0.2298 - 2.638 0.485 - 607.1 1 2 0 -0.0003 12 0 0 0 7.55E+06 0.00E+00 - - - 5.1754 0.9999 221125_WJC_METTL3_EV_vs_WT_F07.08495.08495.2 7.35E-05 22-Dec K.SGGVGGSNTNWK.T "sp|P27694|RFA1_HUMAN,tr|I3L4R8|I3L4R8_HUMAN" 2 1162.5367 1.21 96691 8495 2 1162.537805 582.2756 Replication protein A 70 kDa DNA-binding subunit OS=Homo sapiens OX=9606 GN=RPA1 PE=1 SV=2 8.47 1857.5 - 322564 - - - 0.9505 - 2.163 0.537 - 391.4 1 2 0 0.0011 12 0 0 0 2.24E+07 1.85E+07 - - - 5.0369 0.9967 221125_WJC_METTL3_EV_vs_WT_F07.08496.08496.2 3.73E-05 18-Nov R.SVEQEENKWK.V "sp|Q86UP2|KTN1_HUMAN,tr|B7Z6P3|B7Z6P3_HUMAN,tr|G3V5P0|G3V5P0_HUMAN,tr|G3V4Y7|G3V4Y7_HUMAN" 4 1275.6095 2.03 96692 8496 2 1275.612334 638.812 Kinectin OS=Homo sapiens OX=9606 GN=KTN1 PE=1 SV=1 4.78 1857.7 - 209680 - - - 2.1974 - 2.129 0.518 - 360.1 1 2 1 0.0028 10 0 0 0 1.83E+06 9.00E+05 - - - 4.9753 0.9999 221125_WJC_METTL3_EV_vs_WT_F07.08503.08503.3 8.88E-05 18/32 R.HRPQLLVER.Y "sp|P47897|SYQ_HUMAN,tr|A0A0U1RQL2|A0A0U1RQL2_HUMAN,tr|A0A0U1RRI9|A0A0U1RRI9_HUMAN,tr|C9J165|C9J165_HUMAN,tr|A0A0U1RQT0|A0A0U1RQT0_HUMAN,tr|A0A1B0GVU9|A0A1B0GVU9_HUMAN,tr|A0A0U1RQE9|A0A0U1RQE9_HUMAN,tr|A0A0U1RQM8|A0A0U1RQM8_HUMAN,tr|A0A0U1RQU2|A0A0U1RQU2_HUMAN" 9 1146.6622 1.05 96698 8503 3 1146.664606 383.228 Glutamine--tRNA ligase OS=Homo sapiens OX=9606 GN=QARS1 PE=1 SV=1 9.61 1858.4 - 1.24E+06 - - - 2.1201 - 3.415 0.344 - 747.8 1 2 0 0.0024 9 0 0 0 2.66E+07 2.52E+07 - - - 6.0761 1 221125_WJC_METTL3_EV_vs_WT_F07.08504.08504.2 1.78E-06 13/22 K.SGGVGGSNTNWK[136.11].T "sp|P27694|RFA1_HUMAN,tr|I3L4R8|I3L4R8_HUMAN" 2 1170.5509 1.21 96699 8504 2 1170.552436 586.2827 Replication protein A 70 kDa DNA-binding subunit OS=Homo sapiens OX=9606 GN=RPA1 PE=1 SV=2 8.47 1858.5 - 916666 - - - 1.3122 - 2.449 0.59 - 553.6 1 2 0 0.0015 12 0 0 0 2.24E+07 1.85E+07 - - - 5.7549 0.9992 221125_WJC_METTL3_EV_vs_WT_F07.08516.08516.3 0.0236 Nov-36 K.MVQFEENGR[166.11]K[136.11].E "sp|P49368|TCPG_HUMAN,tr|Q5SZW8|Q5SZW8_HUMAN,tr|E9PRC8|E9PRC8_HUMAN,tr|B4DUR8|B4DUR8_HUMAN,tr|E9PQ35|E9PQ35_HUMAN,tr|Q5SZX6|Q5SZX6_HUMAN" 6 1254.6146 0.34 96708 8516 3 1254.616436 419.2121 T-complex protein 1 subunit gamma OS=Homo sapiens OX=9606 GN=CCT3 PE=1 SV=4 5.9 1859.8 - 2.19E+06 - - - 1.4825 - 1.859 0.302 - 159.9 1 2 0 0.0019 10 0 0 0 1.09E+07 3.19E+07 - - - 3.7173 0.9999 221125_WJC_METTL3_EV_vs_WT_F07.08517.08517.3 4.79E-05 Dec-44 K.TNPPLIQEKPAK.T "sp|P78344|IF4G2_HUMAN,tr|E9PKF8|E9PKF8_HUMAN,tr|H0Y3P2|H0Y3P2_HUMAN,tr|D3DQV9|D3DQV9_HUMAN" 4 1334.7558 2.41 96709 8517 3 1334.758051 445.9259 Eukaryotic translation initiation factor 4 gamma 2 OS=Homo sapiens OX=9606 GN=EIF4G2 PE=1 SV=1 8.26 1859.9 - 1.14E+06 - - - 1.6857 - 2.456 0.417 - 256.6 1 2 0 0.0022 12 0 0 0 7.49E+08 3.10E+08 - - - 5.6791 0.9854 221125_WJC_METTL3_EV_vs_WT_F07.08520.08520.3 0.00723 Oct-44 R.EEEDR[166.11]EVAAAVR[166.11].A "sp|Q86UK7|ZN598_HUMAN,tr|H3BQQ2|H3BQQ2_HUMAN,tr|H3BPG6|H3BPG6_HUMAN" 3 1392.6748 0.75 96712 8520 3 1392.677068 465.2322 E3 ubiquitin-protein ligase ZNF598 OS=Homo sapiens OX=9606 GN=ZNF598 PE=1 SV=1 4.25 1860.2 - 663062 - - - 1.6199 - 1.736 0.245 - 184.2 1 2 1 0.0023 12 0 0 0 6.60E+06 8.78E+06 - - - 2.7998 0.9999 221125_WJC_METTL3_EV_vs_WT_F07.08522.08522.2 0.000342 24-Aug K.NTENNDVEISETK.K "sp|Q5UIP0|RIF1_HUMAN,tr|H7C2B5|H7C2B5_HUMAN" 2 1491.6689 1.08 96714 8522 2 1491.669435 746.8417 Telomere-associated protein RIF1 OS=Homo sapiens OX=9606 GN=RIF1 PE=1 SV=2 4 1860.5 - 444380 - - - 0.3613 - 2.198 0.572 - 206.5 1 2 0 0.0005 13 0 0 0 5.79E+06 5.35E+06 - - - 5.2869 1 221125_WJC_METTL3_EV_vs_WT_F07.08523.08523.2 1.42E-06 24-Dec K.NTENNDVEISETK[136.11].K "sp|Q5UIP0|RIF1_HUMAN,tr|H7C2B5|H7C2B5_HUMAN" 2 1499.6831 1.08 96715 8523 2 1499.686143 750.8488 Telomere-associated protein RIF1 OS=Homo sapiens OX=9606 GN=RIF1 PE=1 SV=2 4 1860.6 - 404094 - - - 2.0318 - 2.702 0.644 - 626.2 1 2 0 0.003 13 0 0 0 5.79E+06 5.35E+06 - - - 6.3477 0.9985 221125_WJC_METTL3_EV_vs_WT_F07.08525.08525.2 0.000103 16-Oct R.HSEIQQLER[166.11].S sp|Q12846|STX4_HUMAN 1 1148.5814 1.64 96717 8525 2 1148.586027 575.298 Syntaxin-4 OS=Homo sapiens OX=9606 GN=STX4 PE=1 SV=2 5.4 1860.9 - 209522 - - - 4.0676 - 1.875 0.492 - 233.1 1 2 0 0.0047 9 0 0 0 6.88E+06 4.19E+06 - - - 4.492 0.997 221125_WJC_METTL3_EV_vs_WT_F07.08526.08526.3 0.0117 Sep-52 R.QVEVHQEPGAAVPR.G "sp|Q9HBR0|S38AA_HUMAN,tr|H0YF92|H0YF92_HUMAN,tr|I3L0Q8|I3L0Q8_HUMAN" 3 1515.7794 0.62 96718 8526 3 1515.780492 506.2671 Putative sodium-coupled neutral amino acid transporter 10 OS=Homo sapiens OX=9606 GN=SLC38A10 PE=1 SV=2 5.4 1861 - 152361 - - - 0.727 - 1.619 0.245 - 90.1 1 2 0 0.0011 14 0 0 0 2.18E+06 3.53E+06 - - - 2.5516 0.9999 221125_WJC_METTL3_EV_vs_WT_F07.08530.08530.3 8.63E-06 Nov-40 R.GLDNTEFQGKR.M "sp|Q9BWF3|RBM4_HUMAN,sp|Q9BQ04|RBM4B_HUMAN,tr|E9PB51|E9PB51_HUMAN" 3 1263.6208 1.14 96720 8530 3 1263.622716 422.2142 RNA-binding protein 4 OS=Homo sapiens OX=9606 GN=RBM4 PE=1 SV=1 6.07 1861.5 - 3.62E+06 - - - 1.5448 - 2.207 0.464 - 144.4 1 2 0 0.002 11 0 0 0 8.55E+07 7.47E+07 - - - 5.9615 1 221125_WJC_METTL3_EV_vs_WT_F07.08531.08531.3 2.63E-08 17/44 R.QSPVDIDTHTAK[136.11].Y "sp|P00918|CAH2_HUMAN,tr|E5RID5|E5RID5_HUMAN,tr|E5RK37|E5RK37_HUMAN" 3 1318.6608 1.26 96721 8531 3 1318.662819 440.5609 Carbonic anhydrase 2 OS=Homo sapiens OX=9606 GN=CA2 PE=1 SV=2 5.21 1861.6 - 2.08E+06 - - - 1.4977 - 2.917 0.551 - 526.7 1 2 0 0.002 12 0 0 0 2.79E+07 2.21E+07 - - - 7.65 0.9999 221125_WJC_METTL3_EV_vs_WT_F07.08532.08532.2 9.92E-10 14/26 K.LAVDEEENADNNTK.A "sp|P02786|TFR1_HUMAN,tr|F8WBE5|F8WBE5_HUMAN" 2 1560.6904 1.34 96722 8532 2 1560.691769 781.3525 Transferrin receptor protein 1 OS=Homo sapiens OX=9606 GN=TFRC PE=1 SV=2 3.83 1861.7 - 959132 - - - 0.9028 - 3.035 0.507 - 556 1 2 0 0.0014 14 0 0 0 1.39E+07 1.04E+07 - - - 5.5713 0.9744 221125_WJC_METTL3_EV_vs_WT_F07.08533.08533.3 0.161 Nov-44 K.GQIEEQKEMMEK.A sp|O94906|PRP6_HUMAN 1 1478.6745 2.19 96723 8533 3 1478.675423 493.8988 Pre-mRNA-processing factor 6 OS=Homo sapiens OX=9606 GN=PRPF6 PE=1 SV=1 4.49 1861.8 - 635126 - - - 0.6141 - 1.496 0.224 - 98.6 1 2 1 0.0009 12 0 0 0 5.94E+06 2.71E+06 - - - 2.1536 0.9994 221125_WJC_METTL3_EV_vs_WT_F07.08534.08534.2 0.0136 16-Oct R.HSEIQQLER.S sp|Q12846|STX4_HUMAN 1 1138.5731 1.64 96724 8534 2 1138.574689 570.2938 Syntaxin-4 OS=Homo sapiens OX=9606 GN=STX4 PE=1 SV=2 5.4 1862 - 516615 - - - 1.4088 - 1.739 0.379 - 243.4 1 2 0 0.0016 9 0 0 0 6.88E+06 4.19E+06 - - - 3.4405 0.9908 221125_WJC_METTL3_EV_vs_WT_F07.08535.08535.3 0.0476 Dec-44 R.EEEDREVAAAVR.A "sp|Q86UK7|ZN598_HUMAN,tr|H3BQQ2|H3BQQ2_HUMAN,tr|H3BPG6|H3BPG6_HUMAN" 3 1372.6583 0.28 96725 8535 3 1372.658861 458.56 E3 ubiquitin-protein ligase ZNF598 OS=Homo sapiens OX=9606 GN=ZNF598 PE=1 SV=1 4.25 1862.1 - 484562 - - - 0.4291 - 1.87 0.229 - 217 1 2 1 0.0006 12 0 0 0 6.85E+06 2.48E+07 - - - 2.828 0.9993 221125_WJC_METTL3_EV_vs_WT_F07.08536.08536.2 0.000157 20-Sep R.GLDNTEFQGK[136.11]R[166.11].M "sp|Q9BWF3|RBM4_HUMAN,sp|Q9BQ04|RBM4B_HUMAN,tr|E9PB51|E9PB51_HUMAN" 3 1281.6432 1.21 96726 8536 2 1281.639058 641.8289 RNA-binding protein 4 OS=Homo sapiens OX=9606 GN=RBM4 PE=1 SV=1 6.07 1862.2 - 369339 - - - -3.2583 - 2.096 0.5 - 268.2 1 2 0 -0.0042 11 0 0 0 9.17E+06 7.60E+06 - - - 4.7346 0.9934 221125_WJC_METTL3_EV_vs_WT_F07.08537.08537.2 1.66E-05 14/22 Q.QSSSYGQQSSFR[166.11].Q "sp|Q01844|EWS_HUMAN,tr|B0QYJ7|B0QYJ7_HUMAN,tr|B0QYK0|B0QYK0_HUMAN,tr|F8WC90|F8WC90_HUMAN" 4 1370.609 0.94 96727 8537 2 1370.609754 686.3118 RNA-binding protein EWS OS=Homo sapiens OX=9606 GN=EWSR1 PE=1 SV=1 8.75 1862.3 - 319920 - - - 0.5304 - 2.725 0.479 - 882.2 1 1 0 0.0007 12 0 0 0 3.16E+06 3.35E+06 - - - 5.2163 0.9998 221125_WJC_METTL3_EV_vs_WT_F07.08538.08538.2 9.70E-06 26-Dec R.SGAQASSTPLSPTR.L "sp|P02545|LMNA_HUMAN,tr|A0A6Q8PFF5|A0A6Q8PFF5_HUMAN,tr|A0A6Q8PF80|A0A6Q8PF80_HUMAN,tr|A0A804HL68|A0A804HL68_HUMAN,tr|A0A6Q8PFM1|A0A6Q8PFM1_HUMAN,tr|A0A6Q8PF59|A0A6Q8PF59_HUMAN,tr|A0A6Q8PFJ0|A0A6Q8PFJ0_HUMAN,tr|A0A6Q8PHQ9|A0A6Q8PHQ9_HUMAN,tr|A0A6Q8PGH0|A0A6Q8PGH0_HUMAN,tr|Q3BDU5|Q3BDU5_HUMAN" 10 1358.679 2.43 96728 8538 2 1358.681865 680.3468 Prelamin-A\C OS=Homo sapiens OX=9606 GN=LMNA PE=1 SV=1 9.47 1862.4 - 314945 - - - 2.1035 - 2.623 0.523 - 494.3 1 2 0 0.0029 14 0 0 0 4.36E+07 1.79E+07 - - - 5.3229 0.9999 221125_WJC_METTL3_EV_vs_WT_F07.08539.08539.3 0.000209 Nov-52 K.VLDANSC[160.03]QSELHEK[136.11].Y "sp|Q7KZI7|MARK2_HUMAN,tr|A0A0A0MRU9|A0A0A0MRU9_HUMAN,tr|E7ETY4|E7ETY4_HUMAN,tr|A0A7I2YQR3|A0A7I2YQR3_HUMAN,tr|E9PC69|E9PC69_HUMAN" 5 1636.7606 0.68 96729 8539 3 1636.759416 546.5942 Serine\threonine-protein kinase MARK2 OS=Homo sapiens OX=9606 GN=MARK2 PE=1 SV=2 4.65 1862.6 - 273474 - - - -0.7448 - 2.081 0.417 - 140.8 1 2 0 -0.0012 14 0 0 0 3.22E+06 4.75E+06 - - - 5.1364 0.9999 221125_WJC_METTL3_EV_vs_WT_F07.08543.08543.3 0.000495 Nov-40 R.GLDNTEFQGK[136.11]R[166.11].M "sp|Q9BWF3|RBM4_HUMAN,sp|Q9BQ04|RBM4B_HUMAN,tr|E9PB51|E9PB51_HUMAN" 3 1281.6432 1.15 96731 8543 3 1281.643826 428.2217 RNA-binding protein 4 OS=Homo sapiens OX=9606 GN=RBM4 PE=1 SV=1 6.07 1863.1 - 5.72E+06 - - - 0.4619 - 1.925 0.405 - 139.6 1 2 0 0.0006 11 0 0 0 8.53E+07 7.44E+07 - - - 4.9157 0.9999 221125_WJC_METTL3_EV_vs_WT_F07.08546.08546.3 2.14E-06 13/48 K.FVTSNTQELGK[136.11]DK[136.11].W "sp|Q9BXP5|SRRT_HUMAN,tr|H7C3A1|H7C3A1_HUMAN" 2 1481.7697 1.48 96734 8546 3 1481.771058 494.9305 Serrate RNA effector molecule homolog OS=Homo sapiens OX=9606 GN=SRRT PE=1 SV=1 6.07 1863.3 - 1.10E+06 - - - 0.9347 - 2.41 0.528 - 107.3 1 2 1 0.0014 13 0 0 0 4.08E+07 2.76E+07 - - - 6.8112 0.9829 221125_WJC_METTL3_EV_vs_WT_F07.08547.08547.3 0.427 Sep-40 K.SQEDTEAVFK[136.11]K[136.11].A sp|Q9NYH9|UTP6_HUMAN 1 1296.6532 3.04 96735 8547 3 1296.655295 433.225 U3 small nucleolar RNA-associated protein 6 homolog OS=Homo sapiens OX=9606 GN=UTP6 PE=1 SV=2 4.68 1863.3 - 997647 - - - 1.5802 - 1.473 0.187 - 95.7 1 2 0 0.002 11 0 0 0 3.19E+07 1.05E+07 - - - 1.7246 0.9861 221125_WJC_METTL3_EV_vs_WT_F07.08551.08551.2 0.000723 18-Aug K.YK[136.11]DLVPDNSK[136.11].T "sp|Q9Y224|RTRAF_HUMAN,tr|G3V4C6|G3V4C6_HUMAN,tr|H0YJB9|H0YJB9_HUMAN" 3 1193.6263 1.23 96739 8551 2 1193.629779 597.8204 "RNA transcription, translation and transport factor protein OS=Homo sapiens OX=9606 GN=RTRAF PE=1 SV=1" 5.96 1863.8 - 335989 - - - 2.9121 - 1.787 0.4 - 156.1 1 2 1 0.0035 10 0 0 0 2.48E+07 2.03E+07 - - - 3.6148 0.9995 221125_WJC_METTL3_EV_vs_WT_F07.08552.08552.3 0.000385 Oct-52 R.VVGPQQLHSETNER[166.11].L sp|Q9BSF4|TIM29_HUMAN 1 1602.799 0.69 96740 8552 3 1602.802572 535.2736 Mitochondrial import inner membrane translocase subunit Tim29 OS=Homo sapiens OX=9606 GN=TIMM29 PE=1 SV=2 5.4 1863.9 - 284579 - - - 2.2579 - 1.806 0.397 - 116.7 1 2 0 0.0036 14 0 0 0 7.53E+06 1.09E+07 - - - 4.5361 0.9997 221125_WJC_METTL3_EV_vs_WT_F07.08553.08553.3 0.000195 Nov-52 K.VLDANSC[160.03]QSELHEK.Y "sp|Q7KZI7|MARK2_HUMAN,tr|A0A0A0MRU9|A0A0A0MRU9_HUMAN,tr|E7ETY4|E7ETY4_HUMAN,tr|A0A7I2YQR3|A0A7I2YQR3_HUMAN,tr|E9PC69|E9PC69_HUMAN" 5 1628.7464 0.68 96741 8553 3 1628.751524 543.9228 Serine\threonine-protein kinase MARK2 OS=Homo sapiens OX=9606 GN=MARK2 PE=1 SV=2 4.65 1864.1 - 266164 - - - 3.1245 - 2.065 0.458 - 148.3 1 2 0 0.0051 14 0 0 0 3.22E+06 4.75E+06 - - - 5.5719 0.9991 221125_WJC_METTL3_EV_vs_WT_F07.08554.08554.2 0.000161 20-Aug R.ADTQTYQPYNK.D sp|P84090|ERH_HUMAN 1 1327.6044 2.25 96742 8554 2 1327.605279 664.8095 Enhancer of rudimentary homolog OS=Homo sapiens OX=9606 GN=ERH PE=1 SV=1 5.88 1864.2 - 237645 - - - 0.6282 - 1.719 0.28 - 238.4 1 2 0 0.0008 11 0 0 0 3.84E+06 1.71E+06 - - - 2.5744 0.9856 221125_WJC_METTL3_EV_vs_WT_F07.08555.08555.3 3.27E-06 14/60 Q.LTALAAQQQAAGKEEK.S sp|Q96A49|SYAP1_HUMAN 1 1655.8842 1.95 96743 8555 3 1655.885609 552.9687 Synapse-associated protein 1 OS=Homo sapiens OX=9606 GN=SYAP1 PE=1 SV=1 6.14 1864.3 - 226655 - - - 0.8213 - 2.711 0.487 - 235.2 1 1 1 0.0014 16 0 0 0 4.49E+06 2.30E+06 - - - 6.5282 0.9985 221125_WJC_METTL3_EV_vs_WT_F07.08557.08557.2 0.00405 22-Jun K.TNPPLIQEKPAK.T "sp|P78344|IF4G2_HUMAN,tr|E9PKF8|E9PKF8_HUMAN,tr|H0Y3P2|H0Y3P2_HUMAN,tr|D3DQV9|D3DQV9_HUMAN" 4 1334.7558 2.5 96745 8557 2 1334.758798 668.3852 Eukaryotic translation initiation factor 4 gamma 2 OS=Homo sapiens OX=9606 GN=EIF4G2 PE=1 SV=1 8.26 1864.6 - 194676 - - - 2.2454 - 1.595 0.362 - 80.2 1 2 0 0.003 12 0 0 0 4.69E+07 1.87E+07 - - - 2.9422 0.9986 221125_WJC_METTL3_EV_vs_WT_F07.08561.08561.3 0.00056 Dec-40 K.NKFDVDAADEK.F sp|Q9H0D6|XRN2_HUMAN 1 1250.5779 1.15 96747 8561 3 1250.580504 417.8666 5'-3' exoribonuclease 2 OS=Homo sapiens OX=9606 GN=XRN2 PE=1 SV=1 4.23 1865.1 - 3.44E+06 - - - 2.0854 - 2.36 0.343 - 321.8 1 2 1 0.0026 11 0 0 0 1.11E+08 9.63E+07 - - - 4.8027 0.9987 221125_WJC_METTL3_EV_vs_WT_F07.08563.08563.2 2.07E-07 20-Dec K.NK[136.11]FDVDAADEK[136.11].F sp|Q9H0D6|XRN2_HUMAN 1 1266.6063 1.16 96749 8563 2 1266.607112 634.3104 5'-3' exoribonuclease 2 OS=Homo sapiens OX=9606 GN=XRN2 PE=1 SV=1 4.23 1865.3 - 1.21E+06 - - - 0.6442 - 2.477 0.498 - 460.8 1 2 1 0.0008 11 0 0 0 4.75E+07 4.08E+07 - - - 5.1728 1 221125_WJC_METTL3_EV_vs_WT_F07.08564.08564.2 3.97E-06 20-Nov K.NKFDVDAADEK.F sp|Q9H0D6|XRN2_HUMAN 1 1250.5779 1.16 96750 8564 2 1250.579525 626.2962 5'-3' exoribonuclease 2 OS=Homo sapiens OX=9606 GN=XRN2 PE=1 SV=1 4.23 1865.3 - 1.20E+06 - - - 1.3026 - 2.558 0.59 - 342.9 1 2 1 0.0016 11 0 0 0 4.75E+07 4.08E+07 - - - 5.9391 0.995 221125_WJC_METTL3_EV_vs_WT_F07.08566.08566.3 0.00459 Oct-44 R.SAEEVEEIKAEK.E sp|Q8WUA2|PPIL4_HUMAN 1 1360.6722 0.61 96752 8566 3 1360.673414 454.5647 Peptidyl-prolyl cis-trans isomerase-like 4 OS=Homo sapiens OX=9606 GN=PPIL4 PE=1 SV=1 4.32 1865.6 - 510237 - - - 0.8996 - 1.594 0.31 - 114.6 1 2 1 0.0012 12 0 0 0 1.52E+07 2.50E+07 - - - 3.2882 0.9928 221125_WJC_METTL3_EV_vs_WT_F07.08568.08568.2 9.93E-07 13/18 N.PPLIQEKPAK.T "sp|P78344|IF4G2_HUMAN,tr|E9PKF8|E9PKF8_HUMAN,tr|H0Y3P2|H0Y3P2_HUMAN,tr|D3DQV9|D3DQV9_HUMAN" 4 1119.6652 2.66 96754 8568 2 1119.666325 560.8399 Eukaryotic translation initiation factor 4 gamma 2 OS=Homo sapiens OX=9606 GN=EIF4G2 PE=1 SV=1 9.01 1865.7 - 459087 - - - 1.0092 - 2.433 0.531 - 620.8 1 1 0 0.0011 10 0 0 0 5.55E+07 2.08E+07 - - - 5.4444 1 221125_WJC_METTL3_EV_vs_WT_F07.08570.08570.2 3.20E-08 13/26 R.SGAQASSTPLSPTR[166.11].L "sp|P02545|LMNA_HUMAN,tr|A0A6Q8PFF5|A0A6Q8PFF5_HUMAN,tr|A0A6Q8PF80|A0A6Q8PF80_HUMAN,tr|A0A804HL68|A0A804HL68_HUMAN,tr|A0A6Q8PFM1|A0A6Q8PFM1_HUMAN,tr|A0A6Q8PF59|A0A6Q8PF59_HUMAN,tr|A0A6Q8PFJ0|A0A6Q8PFJ0_HUMAN,tr|A0A6Q8PHQ9|A0A6Q8PHQ9_HUMAN,tr|A0A6Q8PGH0|A0A6Q8PGH0_HUMAN,tr|Q3BDU5|Q3BDU5_HUMAN" 10 1368.6873 2.43 96756 8570 2 1368.689535 685.3509 Prelamin-A\C OS=Homo sapiens OX=9606 GN=LMNA PE=1 SV=1 9.47 1866 - 361419 - - - 1.6498 - 2.718 0.576 - 667.2 1 2 0 0.0023 14 0 0 0 4.36E+07 1.79E+07 - - - 5.8038 0.9995 221125_WJC_METTL3_EV_vs_WT_F07.08576.08576.2 0.00139 16-Aug K.QDSGHLDLR[166.11].N "sp|Q86U44|MTA70_HUMAN,tr|B4E349|B4E349_HUMAN,tr|F5H6D8|F5H6D8_HUMAN,tr|B4DTN4|B4DTN4_HUMAN" 4 1049.5129 0 96760 8576 2 1049.514433 525.7637 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 5.21 1866.8 - 1.62E+06 - - - 1.4216 - 1.748 0.396 - 200.5 1 2 0 0.0015 9 0 0 0 5.73E+04 3.08E+07 - - - 3.5811 1 221125_WJC_METTL3_EV_vs_WT_F07.08580.08580.2 8.32E-06 26-Dec K.LAVDEEENADNNTK[136.11].A "sp|P02786|TFR1_HUMAN,tr|F8WBE5|F8WBE5_HUMAN" 2 1568.7046 1.34 96764 8580 2 1568.705316 785.3596 Transferrin receptor protein 1 OS=Homo sapiens OX=9606 GN=TFRC PE=1 SV=2 3.83 1867.3 - 418381 - - - 0.4819 - 2.785 0.612 - 371.9 1 2 0 0.0008 14 0 0 0 1.39E+07 1.04E+07 - - - 6.1313 1 221125_WJC_METTL3_EV_vs_WT_F07.08581.08581.2 1.59E-08 13/22 K.LFQEC[160.03]C[160.03]PHSTDR.V "sp|P61978|HNRPK_HUMAN,tr|Q5T6W2|Q5T6W2_HUMAN" 2 1548.6449 1.46 96765 8581 2 1548.644841 775.3297 Heterogeneous nuclear ribonucleoprotein K OS=Homo sapiens OX=9606 GN=HNRNPK PE=1 SV=1 5.32 1867.4 - 387354 - - - -0.0684 - 2.551 0.642 - 686.6 1 2 0 -0.0001 12 0 0 0 1.38E+07 9.47E+06 - - - 6.2468 0.9976 221125_WJC_METTL3_EV_vs_WT_F07.08583.08583.2 0.0458 18-Aug R.RGTTVYLC[160.03]EK.R "sp|Q9Y2L1|RRP44_HUMAN,tr|F2Z2C0|F2Z2C0_HUMAN,tr|G3V1J5|G3V1J5_HUMAN" 3 1225.6125 1.01 96767 8583 2 1225.609486 613.8135 Exosome complex exonuclease RRP44 OS=Homo sapiens OX=9606 GN=DIS3 PE=1 SV=2 8.2 1867.7 - 189090 - - - -2.4657 - 1.774 0.262 - 223.3 1 2 0 -0.003 10 0 0 0 3.80E+06 3.78E+06 - - - 2.5753 1 221125_WJC_METTL3_EV_vs_WT_F07.08584.08584.2 6.99E-06 18-Nov F.QEC[160.03]C[160.03]PHSTDR.V "sp|P61978|HNRPK_HUMAN,tr|Q5T6W2|Q5T6W2_HUMAN" 2 1288.4925 2.02 96768 8584 2 1288.49083 645.2535 Heterogeneous nuclear ribonucleoprotein K OS=Homo sapiens OX=9606 GN=HNRNPK PE=1 SV=1 5.32 1867.8 - 91329.5 - - - -1.272 - 2.19 0.666 - 601 1 1 0 -0.0016 10 0 0 0 3.86E+06 1.91E+06 - - - 6.1477 0.9978 221125_WJC_METTL3_EV_vs_WT_F07.08589.08589.2 4.05E-05 18-Dec K.YKDLVPDNSK.T "sp|Q9Y224|RTRAF_HUMAN,tr|G3V4C6|G3V4C6_HUMAN,tr|H0YJB9|H0YJB9_HUMAN" 3 1177.5979 1.23 96771 8589 2 1177.59924 589.8062 "RNA transcription, translation and transport factor protein OS=Homo sapiens OX=9606 GN=RTRAF PE=1 SV=1" 5.96 1868.3 - 903794 - - - 1.1354 - 1.947 0.506 - 413.7 1 2 1 0.0013 10 0 0 0 2.48E+07 2.03E+07 - - - 4.6377 0.9998 221125_WJC_METTL3_EV_vs_WT_F07.08592.08592.2 0.000911 22-Nov K.TNPPLIQEK[136.11]PAK[136.11].T "sp|P78344|IF4G2_HUMAN,tr|E9PKF8|E9PKF8_HUMAN,tr|H0Y3P2|H0Y3P2_HUMAN,tr|D3DQV9|D3DQV9_HUMAN" 4 1350.7842 2.5 96774 8592 2 1350.784831 676.3994 Eukaryotic translation initiation factor 4 gamma 2 OS=Homo sapiens OX=9606 GN=EIF4G2 PE=1 SV=1 8.26 1868.7 - 456907 - - - 0.4664 - 1.605 0.507 - 264 1 2 0 0.0006 12 0 0 0 4.69E+07 1.87E+07 - - - 4.0304 0.9856 221125_WJC_METTL3_EV_vs_WT_F07.08595.08595.2 0.193 18-Jul R.R[166.11]GTTVYLC[160.03]EK[136.11].R "sp|Q9Y2L1|RRP44_HUMAN,tr|F2Z2C0|F2Z2C0_HUMAN,tr|G3V1J5|G3V1J5_HUMAN" 3 1243.635 1.62 96777 8595 2 1243.639302 622.8248 Exosome complex exonuclease RRP44 OS=Homo sapiens OX=9606 GN=DIS3 PE=1 SV=2 8.2 1869.1 - 183607 - - - 3.4769 - 1.619 0.178 - 175.8 1 2 0 0.0043 10 0 0 0 3.70E+06 2.29E+06 - - - 1.6992 0.9992 221125_WJC_METTL3_EV_vs_WT_F07.08598.08598.3 0.000759 Nov-40 R.QAHLTNQYMQR.M "sp|P11940|PABP1_HUMAN,tr|A0A7I2YQE4|A0A7I2YQE4_HUMAN,tr|A0A7I2V649|A0A7I2V649_HUMAN,tr|H0YB86|H0YB86_HUMAN,tr|H0YAR2|H0YAR2_HUMAN,tr|E7ERJ7|E7ERJ7_HUMAN,tr|A0A7I2YQ88|A0A7I2YQ88_HUMAN,tr|A0A087WTT1|A0A087WTT1_HUMAN,tr|A0A7I2YQ90|A0A7I2YQ90_HUMAN,tr|A0A7I2V4N4|A0A7I2V4N4_HUMAN,tr|E7EQV3|E7EQV3_HUMAN" 11 1388.6619 0.92 96778 8598 3 1388.665966 463.8946 Polyadenylate-binding protein 1 OS=Homo sapiens OX=9606 GN=PABPC1 PE=1 SV=2 8.75 1869.5 - 3.22E+06 - - - 2.9158 - 1.88 0.376 - 192 1 2 0 0.004 11 0 0 0 6.45E+08 7.03E+08 - - - 4.5242 1 221125_WJC_METTL3_EV_vs_WT_F07.08599.08599.3 7.09E-05 13/44 R.NMSVIAHVDHGK[136.11].S sp|P13639|EF2_HUMAN 1 1314.6594 0.26 96779 8599 3 1314.660908 439.2271 Elongation factor 2 OS=Homo sapiens OX=9606 GN=EEF2 PE=1 SV=4 6.92 1869.6 - 1.18E+06 - - - 1.1433 - 3.124 0.434 - 317.7 1 2 0 0.0015 12 0 0 0 9.95E+06 3.78E+07 - - - 6.5357 1 221125_WJC_METTL3_EV_vs_WT_F07.08602.08602.2 1.07E-09 22-Dec K.LFQEC[160.03]C[160.03]PHSTDR[166.11].V "sp|P61978|HNRPK_HUMAN,tr|Q5T6W2|Q5T6W2_HUMAN" 2 1558.6532 1.46 96782 8602 2 1558.654172 780.3339 Heterogeneous nuclear ribonucleoprotein K OS=Homo sapiens OX=9606 GN=HNRNPK PE=1 SV=1 5.32 1869.8 - 760264 - - - 0.6127 - 2.674 0.672 - 684.5 1 2 0 0.001 12 0 0 0 1.38E+07 9.47E+06 - - - 6.592 0.98 221125_WJC_METTL3_EV_vs_WT_F07.08606.08606.2 0.000807 22-Aug R.SAEEVEEIK[136.11]AEK[136.11].E sp|Q8WUA2|PPIL4_HUMAN 1 1376.7006 1.06 96786 8606 2 1376.705847 689.3576 Peptidyl-prolyl cis-trans isomerase-like 4 OS=Homo sapiens OX=9606 GN=PPIL4 PE=1 SV=1 4.32 1870.3 - 225431 - - - 3.8185 - 1.96 0.428 - 196.4 1 2 1 0.0053 12 0 0 0 2.73E+06 2.57E+06 - - - 3.9712 0.9998 221125_WJC_METTL3_EV_vs_WT_F07.08609.08609.3 1.60E-05 Nov-48 K.FVTSNTQELGKDK.W "sp|Q9BXP5|SRRT_HUMAN,tr|H7C3A1|H7C3A1_HUMAN" 2 1465.7413 1.14 96788 8609 3 1465.741787 489.5877 Serrate RNA effector molecule homolog OS=Homo sapiens OX=9606 GN=SRRT PE=1 SV=1 6.07 1870.7 - 1.65E+06 - - - 0.3507 - 2.035 0.48 - 91.8 1 2 1 0.0005 13 0 0 0 4.01E+07 3.53E+07 - - - 5.8177 0.9999 221125_WJC_METTL3_EV_vs_WT_F07.08611.08611.3 0.000373 Oct-40 R.VPLHK[136.11]PTDWQK[136.11].K "sp|Q96A26|F162A_HUMAN,tr|F8W7Q4|F8W7Q4_HUMAN,tr|E9PH05|E9PH05_HUMAN" 3 1363.7583 1.11 96789 8611 3 1363.760209 455.5934 Protein FAM162A OS=Homo sapiens OX=9606 GN=FAM162A PE=1 SV=2 8.57 1870.9 - 1.22E+06 - - - 1.3851 - 1.905 0.436 - 141.4 1 2 0 0.0019 11 0 0 0 2.76E+07 2.48E+07 - - - 5.2313 0.9999 221125_WJC_METTL3_EV_vs_WT_F07.08613.08613.2 1.81E-08 20-Dec R.QAHLTNQYMQR.M "sp|P11940|PABP1_HUMAN,tr|A0A7I2YQE4|A0A7I2YQE4_HUMAN,tr|A0A7I2V649|A0A7I2V649_HUMAN,tr|H0YB86|H0YB86_HUMAN,tr|H0YAR2|H0YAR2_HUMAN,tr|E7ERJ7|E7ERJ7_HUMAN,tr|A0A7I2YQ88|A0A7I2YQ88_HUMAN,tr|A0A087WTT1|A0A087WTT1_HUMAN,tr|A0A7I2YQ90|A0A7I2YQ90_HUMAN,tr|A0A7I2V4N4|A0A7I2V4N4_HUMAN,tr|E7EQV3|E7EQV3_HUMAN" 11 1388.6619 1.03 96791 8613 2 1388.662445 695.3382 Polyadenylate-binding protein 1 OS=Homo sapiens OX=9606 GN=PABPC1 PE=1 SV=2 8.75 1871.1 - 695855 - - - 0.3802 - 2.264 0.567 - 556.7 1 2 0 0.0005 11 0 0 0 4.78E+07 4.63E+07 - - - 5.4392 0.9868 221125_WJC_METTL3_EV_vs_WT_F07.08617.08617.2 8.34E-06 20-Sep L.FQEC[160.03]C[160.03]PHSTDR.V "sp|P61978|HNRPK_HUMAN,tr|Q5T6W2|Q5T6W2_HUMAN" 2 1435.5609 1.56 96795 8617 2 1435.563593 718.7877 Heterogeneous nuclear ribonucleoprotein K OS=Homo sapiens OX=9606 GN=HNRNPK PE=1 SV=1 5.32 1871.6 - 180517 - - - 1.8878 - 1.924 0.589 - 199.9 1 1 0 0.0027 11 0 0 0 1.59E+06 1.02E+06 - - - 5.1608 0.9998 221125_WJC_METTL3_EV_vs_WT_F07.08622.08622.2 0.39 20-Dec R.QAHLTNQYMQR[166.11].M "sp|P11940|PABP1_HUMAN,tr|A0A7I2YQE4|A0A7I2YQE4_HUMAN,tr|A0A7I2V649|A0A7I2V649_HUMAN,tr|H0YB86|H0YB86_HUMAN,tr|H0YAR2|H0YAR2_HUMAN,tr|E7ERJ7|E7ERJ7_HUMAN,tr|A0A7I2YQ88|A0A7I2YQ88_HUMAN,tr|A0A087WTT1|A0A087WTT1_HUMAN,tr|A0A7I2YQ90|A0A7I2YQ90_HUMAN,tr|A0A7I2V4N4|A0A7I2V4N4_HUMAN,tr|E7EQV3|E7EQV3_HUMAN" 11 1398.6702 1.03 96798 8622 2 1398.671386 700.3424 Polyadenylate-binding protein 1 OS=Homo sapiens OX=9606 GN=PABPC1 PE=1 SV=2 8.75 1872.2 - 1.29E+06 - - - 0.8572 - 2.274 0.442 - 564 1 2 0 0.0012 11 0 0 0 4.78E+07 4.63E+07 - - - 4.5277 1 221125_WJC_METTL3_EV_vs_WT_F07.08624.08624.2 8.30E-05 28-Dec K.AEQLGAEGNVDESQK.L "sp|Q9NQ29|LUC7L_HUMAN,tr|A8MYV2|A8MYV2_HUMAN,tr|B8ZZ09|B8ZZ09_HUMAN,tr|B8ZZ10|B8ZZ10_HUMAN" 4 1573.722 1.48 96800 8624 2 1573.722429 787.8683 Putative RNA-binding protein Luc7-like 1 OS=Homo sapiens OX=9606 GN=LUC7L PE=1 SV=1 4 1872.5 - 399666 - - - 0.2764 - 2.701 0.595 - 442.4 1 2 0 0.0004 15 0 0 0 4.64E+06 3.12E+06 - - - 5.8784 1 221125_WJC_METTL3_EV_vs_WT_F07.08626.08626.2 6.05E-07 28-Oct K.AEQLGAEGNVDESQK[136.11].L "sp|Q9NQ29|LUC7L_HUMAN,tr|A8MYV2|A8MYV2_HUMAN,tr|B8ZZ09|B8ZZ09_HUMAN,tr|B8ZZ10|B8ZZ10_HUMAN" 4 1581.7362 1.43 96802 8626 2 1581.734984 791.8754 Putative RNA-binding protein Luc7-like 1 OS=Homo sapiens OX=9606 GN=LUC7L PE=1 SV=1 4 1872.8 - 265684 - - - -0.765 - 2.46 0.633 - 277.7 1 2 0 -0.0012 15 0 0 0 4.47E+06 3.12E+06 - - - 5.929 0.9968 221125_WJC_METTL3_EV_vs_WT_F07.08632.08632.3 5.94E-05 13/36 V.VGDAQYHHFR.H sp|P47929|LEG7_HUMAN 1 1228.5738 10.6 96806 8632 3 1228.573982 410.5319 Galectin-7 OS=Homo sapiens OX=9606 GN=LGALS7 PE=1 SV=2 6.89 1873.5 - 1.61E+06 - - - 0.1856 - 2.159 0.512 - 401.9 1 1 0 0.0002 10 0 0 0 3.36E+07 3.17E+06 - - - 6.4959 0.9899 221125_WJC_METTL3_EV_vs_WT_F07.08633.08633.2 0.00223 16-Nov V.GDAQYHHFR.H sp|P47929|LEG7_HUMAN 1 1129.5053 999 96807 8633 2 1129.50729 565.7599 Galectin-7 OS=Homo sapiens OX=9606 GN=LGALS7 PE=1 SV=2 6.92 1873.6 - 837239 - - - 1.7264 - 2.352 0.548 - 784.6 1 1 0 0.0019 9 0 0 0 1.92E+07 0.00E+00 - - - 5.5622 0.9998 221125_WJC_METTL3_EV_vs_WT_F07.08634.08634.4 0.00982 13/78 R.EC[160.03]MHGALSKPAVVR.G "tr|F8W726|F8W726_HUMAN,tr|Q5VU77|Q5VU77_HUMAN" 2 1553.7807 1.8 96808 8634 4 1553.782858 389.4524 Ubiquitin-associated protein 2-like OS=Homo sapiens OX=9606 GN=UBAP2L PE=1 SV=2 8.33 1873.7 - 758191 - - - 1.4191 - 2.378 0.369 - 128.3 1 2 0 0.0022 14 0 0 0 9.95E+06 5.53E+06 - - - 2.7524 1 221125_WJC_METTL3_EV_vs_WT_F07.08635.08635.2 2.94E-06 13/18 V.VGDAQYHHFR.H sp|P47929|LEG7_HUMAN 1 1228.5738 999 96809 8635 2 1228.574982 615.2942 Galectin-7 OS=Homo sapiens OX=9606 GN=LGALS7 PE=1 SV=2 6.89 1873.9 - 494521 - - - 0.9995 - 2.916 0.597 - 1088.4 1 1 0 0.0012 10 0 0 0 1.63E+07 0.00E+00 - - - 6.4373 0.9883 221125_WJC_METTL3_EV_vs_WT_F07.08636.08636.3 0.0117 Dec-44 K.DSLLGDK[136.11]GQTAR[166.11].T sp|P33993|MCM7_HUMAN 1 1277.6694 0.56 96810 8636 3 1277.673279 426.8971 DNA replication licensing factor MCM7 OS=Homo sapiens OX=9606 GN=MCM7 PE=1 SV=4 5.96 1874 - 408326 - - - 2.9976 - 2.081 0.272 - 218.7 1 2 1 0.0038 12 0 0 0 5.03E+06 8.97E+06 - - - 3.6028 0.9965 221125_WJC_METTL3_EV_vs_WT_F07.08641.08641.3 0.00082 Dec-52 R.ADAGHAGVSANMMK.K sp|Q9Y657|SPIN1_HUMAN 1 1358.6071 2.04 96813 8641 3 1358.608587 453.8763 Spindlin-1 OS=Homo sapiens OX=9606 GN=SPIN1 PE=1 SV=3 6.79 1874.7 - 2.05E+06 - - - 1.0908 - 1.824 0.217 - 212.9 1 2 0 0.0015 14 0 0 0 2.98E+07 1.46E+07 - - - 2.5562 0.9999 221125_WJC_METTL3_EV_vs_WT_F07.08648.08648.3 7.64E-06 Dec-48 K.HLPSTEPDPHVVR[166.11].L "sp|Q9BUJ2|HNRL1_HUMAN,tr|M0QYZ0|M0QYZ0_HUMAN,tr|A0A0A0MRA5|A0A0A0MRA5_HUMAN,tr|M0R3F1|M0R3F1_HUMAN,tr|B7Z4B8|B7Z4B8_HUMAN,tr|M0QYI8|M0QYI8_HUMAN,tr|M0QYM5|M0QYM5_HUMAN" 7 1492.7662 1.82 96818 8648 3 1492.76906 498.596 Heterogeneous nuclear ribonucleoprotein U-like protein 1 OS=Homo sapiens OX=9606 GN=HNRNPUL1 PE=1 SV=2 5.99 1875.6 - 580203 - - - 1.9186 - 2.334 0.486 - 225 1 2 0 0.0029 13 0 0 0 1.27E+08 7.00E+07 - - - 6.2557 0.9991 221125_WJC_METTL3_EV_vs_WT_F07.08649.08649.3 0.00446 Sep-44 K.TQNDVLHAENVK[136.11].A "sp|P35241|RADI_HUMAN,tr|A0A2R8Y5S7|A0A2R8Y5S7_HUMAN,tr|A0A2R8Y4H6|A0A2R8Y4H6_HUMAN" 3 1374.6983 0.25 96819 8649 3 1374.701154 459.24 Radixin OS=Homo sapiens OX=9606 GN=RDX PE=1 SV=1 5.29 1875.6 - 788980 - - - 2.0812 - 1.867 0.327 - 75 1 2 0 0.0029 12 0 0 0 7.69E+06 3.02E+07 - - - 3.9155 0.9984 221125_WJC_METTL3_EV_vs_WT_F07.08651.08651.2 0.0232 18-Oct K.R[166.11]FPGYDSESK[136.11].E "sp|P46777|RL5_HUMAN,tr|A0A2R8Y6J3|A0A2R8Y6J3_HUMAN" 2 1202.5687 0.62 96821 8651 2 1202.570581 602.2916 60S ribosomal protein L5 OS=Homo sapiens OX=9606 GN=RPL5 PE=1 SV=3 6.07 1875.9 - 405025 - - - 1.5874 - 1.876 0.225 - 370.4 1 2 0 0.0019 10 0 0 0 8.54E+06 1.37E+07 - - - 2.4584 0.9969 221125_WJC_METTL3_EV_vs_WT_F07.08653.08653.2 0.217 22-Sep K.TEADAEK[136.11]TFEEK[136.11].Q "sp|P19338|NUCL_HUMAN,tr|A0A7I2V506|A0A7I2V506_HUMAN,tr|A0A7I2V2U7|A0A7I2V2U7_HUMAN,tr|A0A7I2V3F3|A0A7I2V3F3_HUMAN,tr|A0A7I2V428|A0A7I2V428_HUMAN,tr|A0A7I2V349|A0A7I2V349_HUMAN,tr|H7BY16|H7BY16_HUMAN,tr|A0A7I2V5M5|A0A7I2V5M5_HUMAN,tr|C9JLB1|C9JLB1_HUMAN" 9 1412.6642 0.84 96823 8653 2 1412.664836 707.3394 Nucleolin OS=Homo sapiens OX=9606 GN=NCL PE=1 SV=3 4.25 1876.1 - 166059 - - - 0.4467 - 2.086 0.376 - 214.3 1 2 1 0.0006 12 0 0 0 1.22E+07 1.46E+07 - - - 3.7525 0.9952 221125_WJC_METTL3_EV_vs_WT_F07.08658.08658.2 0.00047 18-Dec R.SAKEEIAEYR.R "sp|P07197|NFM_HUMAN,tr|E7ESP9|E7ESP9_HUMAN,tr|E7EMV2|E7EMV2_HUMAN" 3 1194.5881 3.62 96826 8658 2 1194.588444 598.3013 Neurofilament medium polypeptide OS=Homo sapiens OX=9606 GN=NEFM PE=1 SV=3 4.78 1876.8 - 651557 - - - 0.3156 - 2.067 0.291 - 489.5 1 2 1 0.0004 10 0 0 0 9.87E+06 2.72E+06 - - - 3.217 0.9999 221125_WJC_METTL3_EV_vs_WT_F07.08663.08663.2 0.00253 20-Nov K.STESLQANVQR[166.11].L "sp|P26373|RL13_HUMAN,tr|J3QSB4|J3QSB4_HUMAN" 2 1241.6239 1 96831 8663 2 1241.623249 621.8193 60S ribosomal protein L13 OS=Homo sapiens OX=9606 GN=RPL13 PE=1 SV=4 5.72 1877.4 - 292938 - - - -0.5638 - 2.417 0.43 - 586.4 1 2 0 -0.0007 11 0 0 0 3.09E+07 3.09E+07 - - - 4.6042 0.9967 221125_WJC_METTL3_EV_vs_WT_F07.08664.08664.2 0.0309 22-May K.SEGDGTQDIVDK.S sp|Q5UIP0|RIF1_HUMAN 1 1262.5626 0.9 96832 8664 2 1262.563864 632.2886 Telomere-associated protein RIF1 OS=Homo sapiens OX=9606 GN=RIF1 PE=1 SV=2 3.84 1877.5 - 131772 - - - 0.9695 - 1.079 0.321 - 72.2 1 2 0 0.0012 12 0 0 0 2.34E+06 2.60E+06 - - - 1.6116 0.9986 221125_WJC_METTL3_EV_vs_WT_F07.08667.08667.3 0.00384 Oct-36 R.SAKEEIAEYR.R "sp|P07197|NFM_HUMAN,tr|E7ESP9|E7ESP9_HUMAN,tr|E7EMV2|E7EMV2_HUMAN" 3 1194.5881 1.43 96833 8667 3 1194.587825 399.2033 Neurofilament medium polypeptide OS=Homo sapiens OX=9606 GN=NEFM PE=1 SV=3 4.78 1877.9 - 1.99E+06 - - - -0.2026 - 1.996 0.326 - 164.5 1 2 1 -0.0002 10 0 0 0 1.74E+07 1.22E+07 - - - 4.193 0.9914 221125_WJC_METTL3_EV_vs_WT_F07.08668.08668.2 0.00958 15/18 N.PPLIQEK[136.11]PAK[136.11].T "sp|P78344|IF4G2_HUMAN,tr|E9PKF8|E9PKF8_HUMAN,tr|H0Y3P2|H0Y3P2_HUMAN,tr|D3DQV9|D3DQV9_HUMAN" 4 1135.6936 2.66 96834 8668 2 1135.694949 568.8541 Eukaryotic translation initiation factor 4 gamma 2 OS=Homo sapiens OX=9606 GN=EIF4G2 PE=1 SV=1 9.01 1878.1 - 681667 - - - 1.1922 - 2.769 0.455 - 1207.5 1 1 0 0.0014 10 0 0 0 5.55E+07 2.08E+07 - - - 5.2441 0.9968 221125_WJC_METTL3_EV_vs_WT_F07.08671.08671.2 0.308 18-Sep K.RFPGYDSESK.E "sp|P46777|RL5_HUMAN,tr|A0A2R8Y6J3|A0A2R8Y6J3_HUMAN" 2 1184.5462 0.62 96837 8671 2 1184.543905 593.2804 60S ribosomal protein L5 OS=Homo sapiens OX=9606 GN=RPL5 PE=1 SV=3 6.07 1878.4 - 363910 - - - -1.9391 - 1.625 0.217 - 273.8 1 2 0 -0.0023 10 0 0 0 8.54E+06 1.37E+07 - - - 1.9982 0.9969 221125_WJC_METTL3_EV_vs_WT_F07.08672.08672.3 0.00324 Sep-44 R.LQEIHPEC[160.03]GPC[160.03]K[136.11].T sp|Q12789|TF3C1_HUMAN 1 1474.6788 0.96 96838 8672 3 1474.680895 492.5669 General transcription factor 3C polypeptide 1 OS=Homo sapiens OX=9606 GN=GTF3C1 PE=1 SV=4 5.4 1878.5 - 319816 - - - 1.4071 - 1.531 0.271 - 78.3 1 2 0 0.0021 12 0 0 0 5.60E+06 5.81E+06 - - - 2.7414 0.9851 221125_WJC_METTL3_EV_vs_WT_F07.08673.08673.2 0.00101 18-Sep R.SAK[136.11]EEIAEYR[166.11].R "sp|P07197|NFM_HUMAN,tr|E7ESP9|E7ESP9_HUMAN,tr|E7EMV2|E7EMV2_HUMAN" 3 1212.6105 3.62 96839 8673 2 1212.61393 607.3125 Neurofilament medium polypeptide OS=Homo sapiens OX=9606 GN=NEFM PE=1 SV=3 4.78 1878.7 - 281151 - - - 2.7981 - 1.653 0.405 - 154.5 1 2 1 0.0034 10 0 0 0 9.87E+06 2.72E+06 - - - 3.4342 0.9992 221125_WJC_METTL3_EV_vs_WT_F07.08678.08678.2 0.00711 20-Oct K.STESLQANVQR.L "sp|P26373|RL13_HUMAN,tr|J3QSB4|J3QSB4_HUMAN" 2 1231.6157 1 96842 8678 2 1231.618601 616.8151 60S ribosomal protein L13 OS=Homo sapiens OX=9606 GN=RPL13 PE=1 SV=4 5.72 1879.2 - 1.50E+06 - - - 2.3725 - 2.353 0.319 - 504.6 1 2 0 0.0029 11 0 0 0 3.08E+07 3.09E+07 - - - 3.7111 0.9999 221125_WJC_METTL3_EV_vs_WT_F07.08680.08680.3 0.0347 13/36 R.GDDSFGDKYR.D "sp|P23588|IF4B_HUMAN,tr|E7EX17|E7EX17_HUMAN" 2 1158.4942 2.35 96844 8680 3 1158.495802 387.172 Eukaryotic translation initiation factor 4B OS=Homo sapiens OX=9606 GN=EIF4B PE=1 SV=2 4.43 1879.4 - 768980 - - - 1.4122 - 2.854 0.509 - 369 1 2 1 0.0016 10 0 0 0 9.02E+06 3.84E+06 - - - 7.2771 0.9972 221125_WJC_METTL3_EV_vs_WT_F07.08683.08683.2 0.00138 18-Aug K.GK[136.11]EVDNFVDK[136.11].L "sp|P48444|COPD_HUMAN,tr|B0YIW6|B0YIW6_HUMAN" 2 1165.595 0.48 96847 8683 2 1165.594437 583.8048 Coatomer subunit delta OS=Homo sapiens OX=9606 GN=ARCN1 PE=1 SV=1 4.56 1879.8 - 348698 - - - -0.4856 - 1.758 0.433 - 152.2 1 2 1 -0.0006 10 0 0 0 1.72E+06 3.60E+06 - - - 3.8137 0.9978 221125_WJC_METTL3_EV_vs_WT_F07.08686.08686.2 0.0277 18-Jun K.SDIASHFSNK[136.11].R "sp|Q9H2P0|ADNP_HUMAN,tr|A0A2R8Y6X0|A0A2R8Y6X0_HUMAN,tr|A0A669KBJ7|A0A669KBJ7_HUMAN" 3 1112.5342 0.89 96850 8686 2 1112.537438 557.2744 Activity-dependent neuroprotector homeobox protein OS=Homo sapiens OX=9606 GN=ADNP PE=1 SV=1 6.46 1880.1 - 255526 - - - 2.9222 - 1.62 0.355 - 81.2 1 2 0 0.0033 10 0 0 0 2.56E+06 2.86E+06 - - - 3.0086 1 221125_WJC_METTL3_EV_vs_WT_F07.08687.08687.2 3.13E-11 17/40 A.AGAAPAGGPAPSTAAAPAEEK.K sp|P05386|RLA1_HUMAN 1 1790.8799 1.79 96851 8687 2 1790.883583 896.4472 60S acidic ribosomal protein P1 OS=Homo sapiens OX=9606 GN=RPLP1 PE=1 SV=1 4.53 1880.3 - 185924 - - - 2.061 - 3.063 0.688 - 550.2 1 1 0 0.0037 21 0 0 0 3.16E+06 1.77E+06 - - - 6.8735 0.9765 221125_WJC_METTL3_EV_vs_WT_F07.08696.08696.3 0.0473 Nov-48 K.QKLDPAASVTGSK.R "sp|P46013|KI67_HUMAN,sp|P46013|KI67_HUMAN" 2 1300.6987 0.84 96858 8696 3 1300.699742 434.5735 Proliferation marker protein Ki-67 OS=Homo sapiens OX=9606 GN=MKI67 PE=1 SV=2 8.59 1881.4 - 382892 - - - 0.8165 - 1.862 0.179 - 154.4 1 2 1 0.0011 13 0 0 0 8.51E+06 1.01E+07 - - - 2.2209 0.9999 221125_WJC_METTL3_EV_vs_WT_F07.08701.08701.3 2.73E-05 Oct-48 K.NC[160.03]TAGAVYTYHEK[136.11].K "sp|Q9Y314|NOSIP_HUMAN,tr|M0QX85|M0QX85_HUMAN,tr|M0R1K2|M0R1K2_HUMAN,tr|M0R3B2|M0R3B2_HUMAN,tr|A0A075B6F9|A0A075B6F9_HUMAN,tr|M0R1T7|M0R1T7_HUMAN" 6 1520.6809 0.6 96863 8701 3 1520.676829 507.9009 Nitric oxide synthase-interacting protein OS=Homo sapiens OX=9606 GN=NOSIP PE=1 SV=1 6.74 1882.1 - 235707 - - - -2.6955 - 1.831 0.559 - 131.3 1 2 0 -0.0041 13 0 0 0 1.83E+06 3.05E+06 - - - 6.4111 0.9998 221125_WJC_METTL3_EV_vs_WT_F07.08703.08703.2 6.36E-06 26-Oct K.SPQPDPVDTPASTK.Q sp|P46013|KI67_HUMAN 1 1438.694 1.38 96865 8703 2 1438.691323 720.3543 Proliferation marker protein Ki-67 OS=Homo sapiens OX=9606 GN=MKI67 PE=1 SV=2 4.21 1882.3 - 160301 - - - -1.8531 - 2.171 0.563 - 246 1 2 0 -0.0027 14 0 0 0 2.68E+06 1.95E+06 - - - 5.1438 0.9985 221125_WJC_METTL3_EV_vs_WT_F07.08704.08704.2 0.0107 20-Aug K.QTYSTEPNNLK[136.11].A "sp|P46779|RL28_HUMAN,tr|H0YMF4|H0YMF4_HUMAN,tr|H0YLP6|H0YLP6_HUMAN,tr|H0YKD8|H0YKD8_HUMAN" 4 1301.6343 0.76 96866 8704 2 1301.634907 651.8244 60S ribosomal protein L28 OS=Homo sapiens OX=9606 GN=RPL28 PE=1 SV=3 6 1882.5 - 156153 - - - 0.4702 - 1.236 0.338 - 163.5 1 2 0 0.0006 11 0 0 0 2.22E+06 2.92E+06 - - - 2.1105 0.9953 221125_WJC_METTL3_EV_vs_WT_F07.08705.08705.2 0.0644 18-Oct K.GKEVDNFVDK.L "sp|P48444|COPD_HUMAN,tr|B0YIW6|B0YIW6_HUMAN" 2 1149.5666 0.48 96867 8705 2 1149.566688 575.7906 Coatomer subunit delta OS=Homo sapiens OX=9606 GN=ARCN1 PE=1 SV=1 4.56 1882.6 - 134814 - - - 0.0739 - 1.9 0.32 - 289.1 1 2 1 0.0001 10 0 0 0 1.69E+06 3.55E+06 - - - 3.1961 0.993 221125_WJC_METTL3_EV_vs_WT_F07.08706.08706.2 1.09E-06 Aug-40 A.AGAAPAGGPAPSTAAAPAEEK[136.11].K sp|P05386|RLA1_HUMAN 1 1798.8941 1.79 96868 8706 2 1798.892698 900.4543 60S acidic ribosomal protein P1 OS=Homo sapiens OX=9606 GN=RPLP1 PE=1 SV=1 4.53 1882.7 - 131954 - - - -0.7749 - 2.2 0.556 - 131.1 1 1 0 -0.0014 21 0 0 0 3.16E+06 1.77E+06 - - - 5.0856 1 221125_WJC_METTL3_EV_vs_WT_F07.08707.08707.2 1.25E-06 13/26 K.NSLQEQQEEEEEAR[166.11].K sp|P35580|MYH10_HUMAN 1 1727.7474 1.32 96869 8707 2 1727.74594 864.881 Myosin-10 OS=Homo sapiens OX=9606 GN=MYH10 PE=1 SV=3 3.9 1882.8 - 103387 - - - -0.8282 - 3.031 0.586 - 835.2 1 2 0 -0.0014 14 0 0 0 1.81E+06 1.37E+06 - - - 6.1515 0.8163 221125_WJC_METTL3_EV_vs_WT_F07.08708.08708.2 1.24 28-Mar R.ASLPC[160.03]SQEEATGGAK.D sp|Q8TF76|HASP_HUMAN 1 1504.6828 0.6 96870 8708 2 1504.686532 753.3487 Serine\threonine-protein kinase haspin OS=Homo sapiens OX=9606 GN=HASPIN PE=1 SV=3 4.53 1883 - 97715.6 - - - 2.4989 - 0.904 0.11 - 14.5 3 2 0 0.0038 15 0 0 0 1.22E+06 2.03E+06 - - - -0.609 0.9991 221125_WJC_METTL3_EV_vs_WT_F07.08709.08709.2 1.19E-06 26-Nov K.SPQPDPVDTPASTK[136.11].Q sp|P46013|KI67_HUMAN 1 1446.7082 1.41 96871 8709 2 1446.712616 724.3614 Proliferation marker protein Ki-67 OS=Homo sapiens OX=9606 GN=MKI67 PE=1 SV=2 4.21 1883.1 - 83227 - - - 3.0601 - 2.148 0.438 - 218.9 1 2 0 0.0044 14 0 0 0 2.49E+06 1.76E+06 - - - 4.1932 0.9988 221125_WJC_METTL3_EV_vs_WT_F07.08713.08713.2 2.86E-08 16/22 K.TEADAEKTFEEK.Q "sp|P19338|NUCL_HUMAN,tr|A0A7I2V506|A0A7I2V506_HUMAN,tr|A0A7I2V2U7|A0A7I2V2U7_HUMAN,tr|A0A7I2V3F3|A0A7I2V3F3_HUMAN,tr|A0A7I2V428|A0A7I2V428_HUMAN,tr|A0A7I2V349|A0A7I2V349_HUMAN,tr|H7BY16|H7BY16_HUMAN,tr|A0A7I2V5M5|A0A7I2V5M5_HUMAN,tr|C9JLB1|C9JLB1_HUMAN" 9 1396.6358 0.84 96873 8713 2 1396.636931 699.3252 Nucleolin OS=Homo sapiens OX=9606 GN=NCL PE=1 SV=3 4.25 1883.6 - 1.14E+06 - - - 0.8062 - 3.25 0.445 - 816.2 1 2 1 0.0011 12 0 0 0 1.22E+07 1.45E+07 - - - 5.4287 0.9998 221125_WJC_METTL3_EV_vs_WT_F07.08714.08714.3 6.03E-05 14/48 R.IRTDENGLC[160.03]PAC[160.03]R.K sp|O95628|CNOT4_HUMAN 1 1560.7137 1.83 96874 8714 3 1560.716196 521.2452 CCR4-NOT transcription complex subunit 4 OS=Homo sapiens OX=9606 GN=CNOT4 PE=1 SV=3 6.06 1883.8 - 475101 - - - 1.6025 - 2.544 0.475 - 268.8 1 2 1 0.0025 13 0 0 0 1.10E+07 6.03E+06 - - - 6.3667 0.9993 221125_WJC_METTL3_EV_vs_WT_F07.08715.08715.3 9.51E-05 Dec-48 R.IR[166.11]TDENGLC[160.03]PAC[160.03]R[166.11].K sp|O95628|CNOT4_HUMAN 1 1580.7302 1.86 96875 8715 3 1580.731289 527.9174 CCR4-NOT transcription complex subunit 4 OS=Homo sapiens OX=9606 GN=CNOT4 PE=1 SV=3 6.06 1883.9 - 375309 - - - 0.6668 - 2.19 0.366 - 205.6 1 2 1 0.0011 13 0 0 0 1.10E+07 5.95E+06 - - - 4.7456 0.9947 221125_WJC_METTL3_EV_vs_WT_F07.08716.08716.3 0.108 Oct-36 R.QTTITSHFAK[136.11].G "sp|P26358|DNMT1_HUMAN,tr|A0A7I2V5D0|A0A7I2V5D0_HUMAN,tr|K7EJL0|K7EJL0_HUMAN,tr|A0A7I2V5F1|A0A7I2V5F1_HUMAN,tr|A0A7I2V5F6|A0A7I2V5F6_HUMAN,tr|A0A7I2V2G5|A0A7I2V2G5_HUMAN,tr|A0A7I2YQA8|A0A7I2YQA8_HUMAN,tr|A0A7I2YQQ0|A0A7I2YQQ0_HUMAN,tr|A0A7I2V311|A0A7I2V311_HUMAN,tr|K7ERQ1|K7ERQ1_HUMAN,tr|K7ENQ6|K7ENQ6_HUMAN,tr|A0A7I2V490|A0A7I2V490_HUMAN,tr|K7ELB1|K7ELB1_HUMAN" 13 1140.6019 0.001 96876 8716 3 1140.60299 381.2079 DNA (cytosine-5)-methyltransferase 1 OS=Homo sapiens OX=9606 GN=DNMT1 PE=1 SV=2 8.76 1884 - 300437 - - - 0.9793 - 1.493 0.228 - 87 1 2 0 0.0011 10 0 0 0 0.00E+00 2.04E+06 - - - 2.2521 1 221125_WJC_METTL3_EV_vs_WT_F07.08718.08718.2 1.10E-09 14/26 K.NSLQEQQEEEEEAR.K sp|P35580|MYH10_HUMAN 1 1717.7391 1.32 96878 8718 2 1717.741756 859.8768 Myosin-10 OS=Homo sapiens OX=9606 GN=MYH10 PE=1 SV=3 3.9 1884.3 - 217183 - - - 1.5456 - 3.077 0.686 - 922.8 1 2 0 0.0027 14 0 0 0 1.81E+06 1.37E+06 - - - 6.9275 0.9998 221125_WJC_METTL3_EV_vs_WT_F07.08720.08720.2 0.000663 30-Jul R.GGPASVPSSSPGTSVK[136.11].K "sp|O43237|DC1L2_HUMAN,tr|J3KRI4|J3KRI4_HUMAN,tr|J3KRZ2|J3KRZ2_HUMAN" 3 1421.7242 0.001 96880 8720 2 1421.724371 711.8694 Cytoplasmic dynein 1 light intermediate chain 2 OS=Homo sapiens OX=9606 GN=DYNC1LI2 PE=1 SV=1 8.75 1884.6 - 162589 - - - 0.1393 - 1.704 0.505 - 86 1 2 0 0.0002 16 0 0 0 0.00E+00 1.19E+06 - - - 4.0812 0.9996 221125_WJC_METTL3_EV_vs_WT_F07.08726.08726.2 6.31E-08 15/28 R.GGDSIGETPTPGASK[136.11].R sp|O75533|SF3B1_HUMAN 1 1380.6612 1.45 96885 8726 2 1380.665338 691.3379 Splicing factor 3B subunit 1 OS=Homo sapiens OX=9606 GN=SF3B1 PE=1 SV=3 4.37 1885.4 - 1.58E+06 - - - 2.9696 - 2.533 0.588 - 661.7 1 2 0 0.0041 15 0 0 0 2.78E+07 1.92E+07 - - - 5.6677 0.9999 221125_WJC_METTL3_EV_vs_WT_F07.08728.08728.3 0.000589 Dec-40 K.IDR[166.11]PEAISEER[166.11].L "sp|Q9Y6B6|SAR1B_HUMAN,tr|D6RD69|D6RD69_HUMAN,tr|D6R9R5|D6R9R5_HUMAN,tr|Q9H029|Q9H029_HUMAN" 4 1333.6741 1.46 96886 8728 3 1333.674352 445.5653 GTP-binding protein SAR1b OS=Homo sapiens OX=9606 GN=SAR1B PE=1 SV=1 4.41 1885.6 - 1.19E+06 - - - 0.2017 - 2.164 0.382 - 266.6 1 2 0 0.0003 11 0 0 0 4.17E+07 2.85E+07 - - - 4.9918 0.9999 221125_WJC_METTL3_EV_vs_WT_F07.08729.08729.3 1.83E-06 13/40 K.EFLHAQEEVK[136.11]R[166.11].L sp|P43686|PRS6B_HUMAN 1 1402.7324 1.04 96887 8729 3 1402.734557 468.5847 26S proteasome regulatory subunit 6B OS=Homo sapiens OX=9606 GN=PSMC4 PE=1 SV=2 5.5 1885.7 - 1.12E+06 - - - 1.5498 - 2.596 0.363 - 341.6 1 2 0 0.0022 11 0 0 0 1.10E+07 1.06E+07 - - - 5.2966 0.9987 221125_WJC_METTL3_EV_vs_WT_F07.08731.08731.3 0.00127 Oct-56 K.YASETLQAQSEEARR.L sp|Q9ULR0|ISY1_HUMAN 1 1737.8282 1.76 96889 8731 3 1737.831342 580.2833 Pre-mRNA-splicing factor ISY1 homolog OS=Homo sapiens OX=9606 GN=ISY1 PE=1 SV=3 4.79 1885.9 - 483382 - - - 1.8132 - 1.729 0.319 - 106.5 1 2 0 0.0032 15 0 0 0 5.00E+06 2.84E+06 - - - 3.5244 1 221125_WJC_METTL3_EV_vs_WT_F07.08732.08732.3 8.00E-08 Dec-48 K.NHIPITEQGDAPR[166.11].T sp|Q8WXD5|GEMI6_HUMAN 1 1456.7298 1.16 96890 8732 3 1456.730723 486.5839 Gem-associated protein 6 OS=Homo sapiens OX=9606 GN=GEMIN6 PE=1 SV=1 5.32 1886.1 - 314595 - - - 0.6261 - 2.657 0.558 - 278.6 1 2 0 0.0009 13 0 0 0 1.20E+07 1.04E+07 - - - 7.4104 0.9996 221125_WJC_METTL3_EV_vs_WT_F07.08733.08733.3 0.00209 Sep-48 K.NC[160.03]TAGAVYTYHEK.K "sp|Q9Y314|NOSIP_HUMAN,tr|M0QX85|M0QX85_HUMAN,tr|M0R1K2|M0R1K2_HUMAN,tr|M0R3B2|M0R3B2_HUMAN,tr|A0A075B6F9|A0A075B6F9_HUMAN,tr|M0R1T7|M0R1T7_HUMAN" 6 1512.6667 0.6 96891 8733 3 1512.670173 505.2295 Nitric oxide synthase-interacting protein OS=Homo sapiens OX=9606 GN=NOSIP PE=1 SV=1 6.74 1886.2 - 284076 - - - 2.2774 - 1.549 0.455 - 97.7 1 2 0 0.0034 13 0 0 0 1.83E+06 3.05E+06 - - - 4.7983 0.798 221125_WJC_METTL3_EV_vs_WT_F07.08734.08734.2 0.695 14-May D.EHTDMC[160.03]K[136.11]R.L "sp|Q6GYQ0|RGPA1_HUMAN,tr|A0A7P0TAR5|A0A7P0TAR5_HUMAN,tr|A0A1B0GUI1|A0A1B0GUI1_HUMAN,tr|H0YJB5|H0YJB5_HUMAN" 4 1083.4681 - 96892 8734 2 1083.468129 542.7413 Ral GTPase-activating protein subunit alpha-1 OS=Homo sapiens OX=9606 GN=RALGAPA1 PE=1 SV=1 6.84 1886.3 - 258947 - - - 0.0277 - 0.883 0.347 - 64.5 1 1 0 0 8 0 0 0 - - - - - 1.2287 0.9997 221125_WJC_METTL3_EV_vs_WT_F07.08736.08736.2 0.00015 16-Oct K.HEQEYMEVR.E "sp|Q15363|TMED2_HUMAN,tr|F5GX39|F5GX39_HUMAN,tr|E7EQ72|E7EQ72_HUMAN" 3 1219.5292 1.48 96894 8736 2 1219.531807 610.7719 Transmembrane emp24 domain-containing protein 2 OS=Homo sapiens OX=9606 GN=TMED2 PE=1 SV=1 4.75 1886.6 - 202255 - - - 2.1607 - 1.778 0.612 - 347.9 1 2 0 0.0026 9 0 0 0 2.54E+06 1.72E+06 - - - 5.2253 0.9997 221125_WJC_METTL3_EV_vs_WT_F07.08746.08746.3 0.00771 13/44 K.TEADAEKTFEEK.Q "sp|P19338|NUCL_HUMAN,tr|A0A7I2V506|A0A7I2V506_HUMAN,tr|A0A7I2V2U7|A0A7I2V2U7_HUMAN,tr|A0A7I2V3F3|A0A7I2V3F3_HUMAN,tr|A0A7I2V428|A0A7I2V428_HUMAN,tr|A0A7I2V349|A0A7I2V349_HUMAN,tr|H7BY16|H7BY16_HUMAN,tr|A0A7I2V5M5|A0A7I2V5M5_HUMAN,tr|C9JLB1|C9JLB1_HUMAN" 9 1396.6358 0.92 96903 8746 3 1396.638919 466.5525 Nucleolin OS=Homo sapiens OX=9606 GN=NCL PE=1 SV=3 4.25 1887.8 - 1.53E+06 - - - 2.2296 - 2.808 0.45 - 300.6 1 2 1 0.0031 12 0 0 0 9.62E+07 1.04E+08 - - - 6.4181 1 221125_WJC_METTL3_EV_vs_WT_F07.08747.08747.3 7.01E-06 14/48 R.KGDEVDGVDEVAK.K "sp|P09874|PARP1_HUMAN,tr|A0A7I2V5E9|A0A7I2V5E9_HUMAN,tr|A0A7I2V625|A0A7I2V625_HUMAN,tr|A0A7I2V3E1|A0A7I2V3E1_HUMAN" 4 1359.6518 1.07 96904 8747 3 1359.655328 454.2245 Poly [ADP-ribose] polymerase 1 OS=Homo sapiens OX=9606 GN=PARP1 PE=1 SV=4 4.11 1887.9 - 2.20E+06 - - - 2.6029 - 3.02 0.556 - 417.5 1 2 0 0.0035 13 0 0 0 2.10E+07 1.97E+07 - - - 7.7345 0.9995 221125_WJC_METTL3_EV_vs_WT_F07.08748.08748.3 0.00369 13/44 R.AVAEQVLHSQSR[166.11].H sp|Q01804|OTUD4_HUMAN 1 1333.6978 2.08 96905 8748 3 1333.702289 445.5732 OTU domain-containing protein 4 OS=Homo sapiens OX=9606 GN=OTUD4 PE=1 SV=4 6.79 1887.9 - 1.16E+06 - - - 3.3793 - 2.081 0.423 - 225.8 1 2 0 0.0045 12 0 0 0 3.65E+07 1.75E+07 - - - 5.2861 0.963 221125_WJC_METTL3_EV_vs_WT_F07.08749.08749.3 0.217 Aug-40 K.FTSDTKPIINK.V "sp|Q8N1F7|NUP93_HUMAN,tr|H3BVG0|H3BVG0_HUMAN" 2 1262.6871 1.29 96906 8749 3 1262.688652 421.903 Nuclear pore complex protein Nup93 OS=Homo sapiens OX=9606 GN=NUP93 PE=1 SV=2 8.59 1888 - 899805 - - - 1.2663 - 1.127 0.205 - 50.1 1 2 0 0.0016 11 0 0 0 7.91E+06 6.13E+06 - - - 1.1648 1 221125_WJC_METTL3_EV_vs_WT_F07.08751.08751.2 4.76E-11 23/24 R.KGDEVDGVDEVAK.K "sp|P09874|PARP1_HUMAN,tr|A0A7I2V5E9|A0A7I2V5E9_HUMAN,tr|A0A7I2V625|A0A7I2V625_HUMAN,tr|A0A7I2V3E1|A0A7I2V3E1_HUMAN" 4 1359.6518 1.55 96908 8751 2 1359.653231 680.8332 Poly [ADP-ribose] polymerase 1 OS=Homo sapiens OX=9606 GN=PARP1 PE=1 SV=4 4.11 1888.2 - 772746 - - - 1.0606 - 4.133 0.693 - 2286.8 1 2 0 0.0014 13 0 0 0 6.13E+06 3.96E+06 - - - 7.801 0.9999 221125_WJC_METTL3_EV_vs_WT_F07.08752.08752.3 9.21E-08 13/48 K.NHIPITEQGDAPR.T sp|Q8WXD5|GEMI6_HUMAN 1 1446.7215 0.7 96909 8752 3 1446.716872 483.2478 Gem-associated protein 6 OS=Homo sapiens OX=9606 GN=GEMIN6 PE=1 SV=1 5.32 1888.3 - 558073 - - - -3.2273 - 2.546 0.532 - 317.3 1 2 0 -0.0047 13 0 0 0 1.38E+07 1.97E+07 - - - 7.0037 0.9999 221125_WJC_METTL3_EV_vs_WT_F07.08753.08753.2 0.00317 14/22 R.AVAEQVLHSQSR.H sp|Q01804|OTUD4_HUMAN 1 1323.6895 2.02 96910 8753 2 1323.691432 662.852 OTU domain-containing protein 4 OS=Homo sapiens OX=9606 GN=OTUD4 PE=1 SV=4 6.79 1888.4 - 531097 - - - 1.4505 - 2.974 0.505 - 959.1 1 2 0 0.0019 12 0 0 0 9.82E+06 4.86E+06 - - - 5.6381 0.9999 221125_WJC_METTL3_EV_vs_WT_F07.08754.08754.3 2.20E-05 Dec-40 R.YSLSGSVAHSR[166.11].D "sp|Q8IX01|SUGP2_HUMAN,tr|M0R216|M0R216_HUMAN,tr|M0R065|M0R065_HUMAN,tr|M0R2Z9|M0R2Z9_HUMAN,tr|M0R3F6|M0R3F6_HUMAN" 5 1172.5814 1.71 96911 8754 3 1172.58254 391.8677 SURP and G-patch domain-containing protein 2 OS=Homo sapiens OX=9606 GN=SUGP2 PE=1 SV=2 8.75 1888.5 - 486433 - - - 1.0106 - 2.295 0.457 - 151.3 1 2 0 0.0012 11 0 0 0 1.69E+07 9.91E+06 - - - 5.9947 0.9999 221125_WJC_METTL3_EV_vs_WT_F07.08755.08755.2 0.000468 14/22 R.AVAEQVLHSQSR[166.11].H sp|Q01804|OTUD4_HUMAN 1 1333.6978 2.02 96912 8755 2 1333.69925 667.8562 OTU domain-containing protein 4 OS=Homo sapiens OX=9606 GN=OTUD4 PE=1 SV=4 6.79 1888.7 - 346021 - - - 1.1007 - 2.923 0.509 - 1016.7 1 2 0 0.0015 12 0 0 0 9.82E+06 4.86E+06 - - - 5.6222 0.8743 221125_WJC_METTL3_EV_vs_WT_F07.08760.08760.3 0.0541 Nov-36 K.TYIPPK[136.11]GETK[136.11].K "sp|B2RPK0|HGB1A_HUMAN,sp|P09429|HMGB1_HUMAN,tr|Q5T7C4|Q5T7C4_HUMAN" 3 1148.6412 0.001 96916 8760 3 1148.642693 383.8877 Putative high mobility group protein B1-like 1 OS=Homo sapiens OX=9606 GN=HMGB1P1 PE=5 SV=1 8.17 1889.2 - 309306 - - - 1.278 - 1.657 0.114 - 169.3 1 2 1 0.0015 10 0 0 0 0.00E+00 3.43E+06 - - - 1.2854 0.9999 221125_WJC_METTL3_EV_vs_WT_F07.08761.08761.3 6.90E-05 Nov-56 K.YASETLQAQSEEAR[166.11]R[166.11].L sp|Q9ULR0|ISY1_HUMAN 1 1757.8447 1.76 96917 8761 3 1757.84692 586.9555 Pre-mRNA-splicing factor ISY1 homolog OS=Homo sapiens OX=9606 GN=ISY1 PE=1 SV=3 4.79 1889.4 - 365479 - - - 1.2453 - 1.855 0.445 - 113.5 1 2 0 0.0022 15 0 0 0 5.00E+06 2.84E+06 - - - 5.113 0.9996 221125_WJC_METTL3_EV_vs_WT_F07.08762.08762.3 0.00335 15/44 R.AVAEQVLHSQSR.H sp|Q01804|OTUD4_HUMAN 1 1323.6895 2.09 96918 8762 3 1323.691365 442.2371 OTU domain-containing protein 4 OS=Homo sapiens OX=9606 GN=OTUD4 PE=1 SV=4 6.79 1889.4 - 4.01E+06 - - - 1.3999 - 2.178 0.319 - 296.5 1 2 0 0.0019 12 0 0 0 3.66E+07 1.75E+07 - - - 4.2537 0.9655 221125_WJC_METTL3_EV_vs_WT_F07.08765.08765.2 0.000678 18-Oct V.AEQVLHSQSR.H sp|Q01804|OTUD4_HUMAN 1 1153.584 0.58 96921 8765 2 1153.587037 577.7993 OTU domain-containing protein 4 OS=Homo sapiens OX=9606 GN=OTUD4 PE=1 SV=4 6.79 1889.7 - 277913 - - - 2.6465 - 2.087 0.44 - 507.1 1 1 0 0.0031 10 0 0 0 2.95E+06 5.09E+06 - - - 4.3435 1 221125_WJC_METTL3_EV_vs_WT_F07.08766.08766.2 1.60E-07 13/24 K.SEDDESGAGELTR.E sp|P33993|MCM7_HUMAN 1 1364.5692 1.13 96922 8766 2 1364.568633 683.2919 DNA replication licensing factor MCM7 OS=Homo sapiens OX=9606 GN=MCM7 PE=1 SV=4 3.83 1889.9 - 220819 - - - -0.4023 - 2.877 0.539 - 731.1 1 2 0 -0.0005 13 0 0 0 5.40E+06 4.77E+06 - - - 5.7341 0.9806 221125_WJC_METTL3_EV_vs_WT_F07.08771.08771.3 0.303 Sep-40 K.SYYK[136.11]PDSPEYK[136.11].A "sp|Q86U86|PB1_HUMAN,tr|H0Y5B5|H0Y5B5_HUMAN,tr|E7EVG2|E7EVG2_HUMAN,tr|C9JPI5|C9JPI5_HUMAN,tr|C9JQF1|C9JQF1_HUMAN" 5 1391.658 1.35 96926 8771 3 1391.663262 464.8933 Protein polybromo-1 OS=Homo sapiens OX=9606 GN=PBRM1 PE=1 SV=1 5.79 1890.5 - 1.08E+06 - - - 3.7833 - 1.457 0.267 - 74.2 1 2 0 0.0053 11 0 0 0 1.66E+07 1.23E+07 - - - 2.5846 0.9999 221125_WJC_METTL3_EV_vs_WT_F07.08777.08777.3 2.08E-05 Dec-44 R.LNQSPSLAPVKR.T "sp|Q9H2P0|ADNP_HUMAN,tr|A0A2R8Y6X0|A0A2R8Y6X0_HUMAN,tr|A0A669KBJ7|A0A669KBJ7_HUMAN" 3 1308.7514 0.88 96931 8777 3 1308.75407 437.2577 Activity-dependent neuroprotector homeobox protein OS=Homo sapiens OX=9606 GN=ADNP PE=1 SV=1 11 1891.2 - 414676 - - - 2.0523 - 2.62 0.456 - 267.7 1 2 0 0.0027 12 0 0 0 4.64E+06 5.30E+06 - - - 6.293 0.9998 221125_WJC_METTL3_EV_vs_WT_F07.08779.08779.2 0.000105 20-Sep K.TPSSWNENPSK.D "sp|Q9UPQ9|TNR6B_HUMAN,tr|H0Y720|H0Y720_HUMAN" 2 1245.5626 1.84 96933 8779 2 1245.564856 623.7886 Trinucleotide repeat-containing gene 6B protein OS=Homo sapiens OX=9606 GN=TNRC6B PE=1 SV=4 5.66 1891.5 - 382867 - - - 1.8273 - 2.005 0.55 - 359.6 1 2 0 0.0023 11 0 0 0 6.53E+06 3.54E+06 - - - 4.9845 0.9998 221125_WJC_METTL3_EV_vs_WT_F07.08782.08782.3 0.0005 Nov-56 R.LTTSPAQNAQQLHER[166.11].L "sp|Q92556|ELMO1_HUMAN,tr|C9JIW2|C9JIW2_HUMAN,tr|C9IZR8|C9IZR8_HUMAN" 3 1702.8626 0.4 96936 8782 3 1702.865948 568.6281 Engulfment and cell motility protein 1 OS=Homo sapiens OX=9606 GN=ELMO1 PE=1 SV=2 6.75 1891.9 - 192658 - - - 1.9567 - 2.162 0.425 - 121.7 1 2 0 0.0033 15 0 0 0 4.89E+05 1.22E+06 - - - 5.2893 0.9315 221125_WJC_METTL3_EV_vs_WT_F07.08783.08783.2 0.0681 18-Apr K.YSQSDLEQTK.T "sp|Q14683|SMC1A_HUMAN,tr|G8JLG1|G8JLG1_HUMAN,tr|A0A6Q8PHC3|A0A6Q8PHC3_HUMAN" 3 1197.5513 0.9 96937 8783 2 1197.556507 599.7829 Structural maintenance of chromosomes protein 1A OS=Homo sapiens OX=9606 GN=SMC1A PE=1 SV=2 4.37 1892 - 166962 - - - 4.3088 - 0.939 0.313 - 31.1 3 2 0 0.0052 10 0 0 0 7.93E+05 8.84E+05 - - - 0.9624 1 221125_WJC_METTL3_EV_vs_WT_F07.08785.08785.2 1.69E-06 26-Nov R.MNSC[160.03]NSSSFGPSGR[166.11].R sp|P17509|HXB6_HUMAN 1 1496.6012 1.89 96939 8785 2 1496.604939 749.3079 Homeobox protein Hox-B6 OS=Homo sapiens OX=9606 GN=HOXB6 PE=1 SV=4 8 1892.3 - 108990 - - - 2.511 - 2.314 0.702 - 339.7 1 2 0 0.0038 14 0 0 0 2.43E+06 1.28E+06 - - - 6.3302 0.9996 221125_WJC_METTL3_EV_vs_WT_F07.08788.08788.3 0.000316 Oct-40 K.SYYKPDSPEYK.A "sp|Q86U86|PB1_HUMAN,tr|H0Y5B5|H0Y5B5_HUMAN,tr|E7EVG2|E7EVG2_HUMAN,tr|C9JPI5|C9JPI5_HUMAN,tr|C9JQF1|C9JQF1_HUMAN" 5 1375.6296 1.1 96940 8788 3 1375.6324 459.5505 Protein polybromo-1 OS=Homo sapiens OX=9606 GN=PBRM1 PE=1 SV=1 5.79 1892.7 - 1.81E+06 - - - 2.0376 - 1.661 0.416 - 84 1 2 0 0.0028 11 0 0 0 1.75E+07 1.59E+07 - - - 4.6187 0.9997 221125_WJC_METTL3_EV_vs_WT_F07.08790.08790.2 0.000299 20-Nov K.QQNEGDSIISK.L "sp|Q15643|TRIPB_HUMAN,tr|H0YJ97|H0YJ97_HUMAN" 2 1217.5888 1.21 96942 8790 2 1217.591126 609.8017 Thyroid receptor-interacting protein 11 OS=Homo sapiens OX=9606 GN=TRIP11 PE=1 SV=3 4.37 1892.8 - 1.07E+06 - - - 1.9144 - 2.114 0.519 - 473.4 1 2 0 0.0023 11 0 0 0 1.32E+08 1.09E+08 - - - 4.8987 0.8421 221125_WJC_METTL3_EV_vs_WT_F07.08791.08791.2 0.0164 16-Jul K.VSELK[136.11]EELK[136.11].K "sp|Q00839|HNRPU_HUMAN,tr|A0A1W2PPS1|A0A1W2PPS1_HUMAN,tr|A0A1X7SBS1|A0A1X7SBS1_HUMAN" 3 1089.6252 0.76 96943 8791 2 1089.628999 545.8199 Heterogeneous nuclear ribonucleoprotein U OS=Homo sapiens OX=9606 GN=HNRNPU PE=1 SV=6 4.79 1893 - 196667 - - - 3.4489 - 1.433 0.203 - 178.6 1 2 1 0.0038 9 0 0 0 1.55E+06 2.06E+06 - - - 1.58 1 221125_WJC_METTL3_EV_vs_WT_F07.08792.08792.2 1.33E-10 14/26 K.TADSEVNTDQDIEK.N "sp|Q8ND24|RN214_HUMAN,tr|E9PN76|E9PN76_HUMAN" 2 1563.69 2.43 96944 8792 2 1563.690719 782.8523 RING finger protein 214 OS=Homo sapiens OX=9606 GN=RNF214 PE=1 SV=2 3.77 1893.1 - 138634 - - - 0.4438 - 2.925 0.681 - 618.7 1 2 0 0.0007 14 0 0 0 1.00E+07 4.12E+06 - - - 6.764 0.9999 221125_WJC_METTL3_EV_vs_WT_F07.08794.08794.2 2.40E-07 22-Nov R.DSDENLTDAEGK[136.11].V "sp|Q69YH5|CDCA2_HUMAN,tr|E9PEI0|E9PEI0_HUMAN" 2 1300.551 0.89 96946 8794 2 1300.552313 651.2828 Cell division cycle-associated protein 2 OS=Homo sapiens OX=9606 GN=CDCA2 PE=1 SV=2 3.77 1893.4 - 125130 - - - 0.995 - 2.358 0.549 - 621.1 1 2 0 0.0013 12 0 0 0 1.12E+06 1.26E+06 - - - 5.3526 1 221125_WJC_METTL3_EV_vs_WT_F07.08795.08795.2 4.46E-08 30-Dec K.IAAESSENVDC[160.03]PENPK[136.11].L sp|Q32MZ4|LRRF1_HUMAN 1 1766.7872 0.77 96947 8795 2 1766.785946 884.4009 Leucine-rich repeat flightless-interacting protein 1 OS=Homo sapiens OX=9606 GN=LRRFIP1 PE=1 SV=2 4 1893.5 - 98798.4 - - - -0.7347 - 2.755 0.703 - 467.7 1 2 0 -0.0013 16 0 0 0 1.58E+06 2.05E+06 - - - 6.7245 0.9998 221125_WJC_METTL3_EV_vs_WT_F07.08797.08797.2 1.55E-06 30-Sep K.IAAESSENVDC[160.03]PENPK.L sp|Q32MZ4|LRRF1_HUMAN 1 1758.773 0.77 96949 8797 2 1758.776698 880.3938 Leucine-rich repeat flightless-interacting protein 1 OS=Homo sapiens OX=9606 GN=LRRFIP1 PE=1 SV=2 4 1893.8 - 72715.2 - - - 2.0776 - 2.226 0.598 - 240 1 2 0 0.0037 16 0 0 0 1.58E+06 2.05E+06 - - - 5.424 1 221125_WJC_METTL3_EV_vs_WT_F07.08799.08799.3 7.86E-06 17/48 K.HLPSTEPDPHVVR.L "sp|Q9BUJ2|HNRL1_HUMAN,tr|M0QYZ0|M0QYZ0_HUMAN,tr|A0A0A0MRA5|A0A0A0MRA5_HUMAN,tr|M0R3F1|M0R3F1_HUMAN,tr|B7Z4B8|B7Z4B8_HUMAN,tr|M0QYI8|M0QYI8_HUMAN,tr|M0QYM5|M0QYM5_HUMAN" 7 1482.7579 1.72 96950 8799 3 1482.761376 495.2599 Heterogeneous nuclear ribonucleoprotein U-like protein 1 OS=Homo sapiens OX=9606 GN=HNRNPUL1 PE=1 SV=2 5.99 1894 - 5.92E+06 - - - 2.3267 - 3.082 0.586 - 472.2 1 2 0 0.0034 13 0 0 0 1.20E+08 6.99E+07 - - - 8.1241 0.9781 221125_WJC_METTL3_EV_vs_WT_F07.08803.08803.3 0.023 Aug-44 R.AQQHWGSGVGVK[136.11].K "sp|P49005|DPOD2_HUMAN,tr|A0A087WWF6|A0A087WWF6_HUMAN,tr|C9J8Z7|C9J8Z7_HUMAN,tr|F8W8R3|F8W8R3_HUMAN,tr|C9IZD2|C9IZD2_HUMAN,tr|C9JLE1|C9JLE1_HUMAN" 6 1260.6455 1.14 96953 8803 3 1260.64986 421.2224 DNA polymerase delta subunit 2 OS=Homo sapiens OX=9606 GN=POLD2 PE=1 SV=1 8.8 1894.4 - 954187 - - - 3.4831 - 1.519 0.239 - 84.3 1 2 0 0.0044 12 0 0 0 8.16E+06 7.15E+06 - - - 2.3622 0.9816 221125_WJC_METTL3_EV_vs_WT_F07.08806.08806.2 0.000236 20-Nov L.SQTQGPPDYPR[166.11].F "sp|Q13405|RM49_HUMAN,tr|E9PNF1|E9PNF1_HUMAN,tr|E9PI78|E9PI78_HUMAN" 3 1254.5868 0.59 96956 8806 2 1254.583905 628.3007 "39S ribosomal protein L49, mitochondrial OS=Homo sapiens OX=9606 GN=MRPL49 PE=1 SV=1" 5.55 1894.7 - 252266 - - - -2.3354 - 2.317 0.496 - 557.1 1 1 0 -0.0029 11 0 0 0 1.90E+06 3.23E+06 - - - 4.9767 1 221125_WJC_METTL3_EV_vs_WT_F07.08808.08808.2 5.47E-09 13/26 K.TADSEVNTDQDIEK[136.11].N "sp|Q8ND24|RN214_HUMAN,tr|E9PN76|E9PN76_HUMAN" 2 1571.7042 2.43 96958 8808 2 1571.707838 786.8594 RING finger protein 214 OS=Homo sapiens OX=9606 GN=RNF214 PE=1 SV=2 3.77 1895 - 163012 - - - 2.2988 - 2.738 0.675 - 583.7 1 2 0 0.0036 14 0 0 0 1.00E+07 4.12E+06 - - - 6.553 0.9905 221125_WJC_METTL3_EV_vs_WT_F07.08809.08809.2 0.0168 20-Jul K.K[136.11]IDASQTEFEK[136.11].N "sp|O94979|SC31A_HUMAN,tr|H0Y9K1|H0Y9K1_HUMAN,tr|H7BXG7|H7BXG7_HUMAN,tr|D6RHZ5|D6RHZ5_HUMAN,tr|D6REX3|D6REX3_HUMAN,tr|H0YAB3|H0YAB3_HUMAN,tr|H0Y8V7|H0Y8V7_HUMAN" 7 1310.6689 6.64 96959 8809 2 1310.672531 656.3417 Protein transport protein Sec31A OS=Homo sapiens OX=9606 GN=SEC31A PE=1 SV=3 4.68 1895.1 - 152521 - - - 2.7734 - 1.485 0.206 - 111.3 1 2 0 0.0036 11 0 0 0 7.49E+06 1.13E+06 - - - 1.6311 0.9999 221125_WJC_METTL3_EV_vs_WT_F07.08811.08811.2 0.00136 18-Oct K.YEELQQTAGR.H "sp|P13647|K2C5_HUMAN,tr|H0YI76|H0YI76_HUMAN,tr|H0YIN9|H0YIN9_HUMAN" 3 1193.5677 0.23 96961 8811 2 1193.56759 597.7911 "Keratin, type II cytoskeletal 5 OS=Homo sapiens OX=9606 GN=KRT5 PE=1 SV=3" 4.53 1895.4 - 92860.5 - - - -0.0637 - 2.151 0.483 - 337.7 1 2 0 -0.0001 10 0 0 0 3.82E+06 1.70E+07 - - - 4.7464 0.9993 221125_WJC_METTL3_EV_vs_WT_F07.08812.08812.2 0.0286 22-Jun R.AQQHWGSGVGVK[136.11].K "sp|P49005|DPOD2_HUMAN,tr|A0A087WWF6|A0A087WWF6_HUMAN,tr|C9J8Z7|C9J8Z7_HUMAN,tr|F8W8R3|F8W8R3_HUMAN,tr|C9IZD2|C9IZD2_HUMAN,tr|C9JLE1|C9JLE1_HUMAN" 6 1260.6455 2.28 96962 8812 2 1260.646092 631.33 DNA polymerase delta subunit 2 OS=Homo sapiens OX=9606 GN=POLD2 PE=1 SV=1 8.8 1895.5 - 80155.4 - - - 0.4942 - 1.271 0.421 - 101 1 2 0 0.0006 12 0 0 0 1.15E+06 5.05E+05 - - - 2.7813 1 221125_WJC_METTL3_EV_vs_WT_F07.08816.08816.3 4.20E-08 13/48 R.ASNGDAWVEAHGK[136.11].L "sp|P38646|GRP75_HUMAN,tr|H0Y8K0|H0Y8K0_HUMAN,tr|A0A7I2V2S7|A0A7I2V2S7_HUMAN,tr|A0A7I2V2G2|A0A7I2V2G2_HUMAN,tr|A0A3B3ITI4|A0A3B3ITI4_HUMAN,tr|A0A7I2V3F7|A0A7I2V3F7_HUMAN,tr|A0A7I2YQB2|A0A7I2YQB2_HUMAN,tr|D6RCD7|D6RCD7_HUMAN" 8 1348.6251 0.38 96964 8816 3 1348.626924 450.549 "Stress-70 protein, mitochondrial OS=Homo sapiens OX=9606 GN=HSPA9 PE=1 SV=2" 5.32 1896.1 - 1.49E+06 - - - 1.3317 - 2.472 0.584 - 270.7 1 2 0 0.0018 13 0 0 0 3.66E+08 9.71E+08 - - - 7.5043 0.9999 221125_WJC_METTL3_EV_vs_WT_F07.08817.08817.3 5.33E-05 Oct-40 K.AAPPQIPDTRR.E sp|Q9HAF1|EAF6_HUMAN 1 1220.6626 1.49 96965 8817 3 1220.664251 407.8948 Chromatin modification-related protein MEAF6 OS=Homo sapiens OX=9606 GN=MEAF6 PE=1 SV=1 9.64 1896.2 - 1.09E+06 - - - 1.3779 - 1.845 0.44 - 131.5 1 2 0 0.0017 11 0 0 0 1.75E+07 1.17E+07 - - - 5.185 0.9997 221125_WJC_METTL3_EV_vs_WT_F07.08822.08822.3 0.00401 Oct-40 K.K[136.11]IDASQTEFEK[136.11].N "sp|O94979|SC31A_HUMAN,tr|H0Y9K1|H0Y9K1_HUMAN,tr|H7BXG7|H7BXG7_HUMAN,tr|D6RHZ5|D6RHZ5_HUMAN,tr|D6REX3|D6REX3_HUMAN,tr|H0YAB3|H0YAB3_HUMAN,tr|H0Y8V7|H0Y8V7_HUMAN" 7 1310.6689 1.65 96970 8822 3 1310.670487 437.8969 Protein transport protein Sec31A OS=Homo sapiens OX=9606 GN=SEC31A PE=1 SV=3 4.68 1896.6 - 544269 - - - 1.2139 - 1.949 0.353 - 155.5 1 2 0 0.0016 11 0 0 0 6.18E+06 3.74E+06 - - - 4.3709 1 221125_WJC_METTL3_EV_vs_WT_F07.08823.08823.3 1.41E-06 Dec-48 R.ASNGDAWVEAHGK.L "sp|P38646|GRP75_HUMAN,tr|H0Y8K0|H0Y8K0_HUMAN,tr|A0A7I2V2S7|A0A7I2V2S7_HUMAN,tr|A0A7I2V2G2|A0A7I2V2G2_HUMAN,tr|A0A3B3ITI4|A0A3B3ITI4_HUMAN,tr|A0A7I2V3F7|A0A7I2V3F7_HUMAN,tr|A0A7I2YQB2|A0A7I2YQB2_HUMAN,tr|D6RCD7|D6RCD7_HUMAN" 8 1340.6109 0.38 96971 8823 3 1340.613553 447.8776 "Stress-70 protein, mitochondrial OS=Homo sapiens OX=9606 GN=HSPA9 PE=1 SV=2" 5.32 1896.7 - 506390 - - - 1.9581 - 2.26 0.543 - 217.3 1 2 0 0.0026 13 0 0 0 3.66E+08 9.70E+08 - - - 6.8039 0.999 221125_WJC_METTL3_EV_vs_WT_F07.08825.08825.3 0.0082 14/40 K.DREVAEGGLPR.A "sp|Q9BUA3|SPNDC_HUMAN,tr|H0YGK9|H0YGK9_HUMAN,tr|H0YGY5|H0YGY5_HUMAN" 3 1197.6102 3.27 96973 8825 3 1197.612596 400.2107 Spindlin interactor and repressor of chromatin-binding protein OS=Homo sapiens OX=9606 GN=SPINDOC PE=1 SV=3 4.68 1896.9 - 412294 - - - 2.0015 - 2.696 0.332 - 280.8 1 2 1 0.0024 11 0 0 0 6.27E+06 1.92E+06 - - - 5.0583 0.9655 221125_WJC_METTL3_EV_vs_WT_F07.08826.08826.3 0.0413 Jun-44 R.YSK[136.11]EEEMDDMDR[166.11].D "sp|Q9HD45|TM9S3_HUMAN,tr|Q5TB53|Q5TB53_HUMAN" 2 1564.614 1.15 96974 8826 3 1564.617636 522.5453 Transmembrane 9 superfamily member 3 OS=Homo sapiens OX=9606 GN=TM9SF3 PE=1 SV=2 4.02 1897.1 - 209028 - - - 2.2958 - 1.26 0.298 - 39.8 1 2 1 0.0036 12 0 0 0 1.73E+06 1.51E+06 - - - 2.502 1 221125_WJC_METTL3_EV_vs_WT_F07.08827.08827.2 1.58E-05 14/24 A.QLSVQQQAAQPTR.W sp|Q9Y5A9|YTHD2_HUMAN 1 1453.7637 1.59 96975 8827 2 1453.767167 727.8891 YTH domain-containing family protein 2 OS=Homo sapiens OX=9606 GN=YTHDF2 PE=1 SV=2 9.75 1897.2 - 190962 - - - 2.3573 - 2.744 0.57 - 804.7 1 1 0 0.0034 13 0 0 0 1.60E+06 1.01E+06 - - - 5.8406 0.8879 221125_WJC_METTL3_EV_vs_WT_F07.08829.08829.2 1.48E-05 24-Nov A.QLSVQQQAAQPTR[166.11].W sp|Q9Y5A9|YTHD2_HUMAN 1 1463.772 1.59 96977 8829 2 1463.779122 732.8933 YTH domain-containing family protein 2 OS=Homo sapiens OX=9606 GN=YTHDF2 PE=1 SV=2 9.75 1897.5 - 140320 - - - 4.8587 - 2.441 0.485 - 413.2 1 1 0 0.0071 13 0 0 0 1.60E+06 1.01E+06 - - - 4.9114 0.9999 221125_WJC_METTL3_EV_vs_WT_F07.08830.08830.2 0.000197 24-Oct R.ASNGDAWVEAHGK[136.11].L "sp|P38646|GRP75_HUMAN,tr|H0Y8K0|H0Y8K0_HUMAN,tr|A0A7I2V2S7|A0A7I2V2S7_HUMAN,tr|A0A7I2V2G2|A0A7I2V2G2_HUMAN,tr|A0A3B3ITI4|A0A3B3ITI4_HUMAN,tr|A0A7I2V3F7|A0A7I2V3F7_HUMAN,tr|A0A7I2YQB2|A0A7I2YQB2_HUMAN,tr|D6RCD7|D6RCD7_HUMAN" 8 1348.6251 0.36 96978 8830 2 1348.623854 675.3198 "Stress-70 protein, mitochondrial OS=Homo sapiens OX=9606 GN=HSPA9 PE=1 SV=2" 5.32 1897.6 - 92137.7 - - - -0.9447 - 2.4 0.578 - 457.6 1 2 0 -0.0013 13 0 0 0 3.36E+07 9.26E+07 - - - 5.5566 0.9998 221125_WJC_METTL3_EV_vs_WT_F07.08832.08832.2 8.02E-05 20-Nov K.QQNEGDSIISK[136.11].L "sp|Q15643|TRIPB_HUMAN,tr|H0YJ97|H0YJ97_HUMAN" 2 1225.603 1.21 96979 8832 2 1225.604982 613.8088 Thyroid receptor-interacting protein 11 OS=Homo sapiens OX=9606 GN=TRIP11 PE=1 SV=3 4.37 1897.8 - 8.84E+06 - - - 1.6212 - 2.337 0.552 - 475.1 1 2 0 0.002 11 0 0 0 1.32E+08 1.09E+08 - - - 5.4138 0.9956 221125_WJC_METTL3_EV_vs_WT_F07.08834.08834.3 0.0054 Nov-40 K.AAPPQIPDTR[166.11]R[166.11].E sp|Q9HAF1|EAF6_HUMAN 1 1240.6791 1.47 96981 8834 3 1240.681936 414.567 Chromatin modification-related protein MEAF6 OS=Homo sapiens OX=9606 GN=MEAF6 PE=1 SV=1 9.64 1898 - 720126 - - - 2.2786 - 1.842 0.233 - 166.3 1 2 0 0.0028 11 0 0 0 1.51E+07 1.03E+07 - - - 2.8723 0.9997 221125_WJC_METTL3_EV_vs_WT_F07.08835.08835.3 0.00354 Oct-40 R.VR[166.11]EEEIEVDSR[166.11].V "sp|Q14978|NOLC1_HUMAN,tr|A0A0A0MRM9|A0A0A0MRM9_HUMAN" 2 1379.6796 3.97 96982 8835 3 1379.679071 460.9005 Nucleolar and coiled-body phosphoprotein 1 OS=Homo sapiens OX=9606 GN=NOLC1 PE=1 SV=2 4.25 1898.1 - 706942 - - - -0.3566 - 2.333 0.406 - 195.2 1 2 1 -0.0005 11 0 0 0 8.55E+08 2.15E+08 - - - 5.473 0.999 221125_WJC_METTL3_EV_vs_WT_F07.08837.08837.3 2.66E-05 13/56 K.AIQEEEERDQALQAK.A "sp|P13994|YJU2B_HUMAN,tr|K7ELI4|K7ELI4_HUMAN,tr|K7ES43|K7ES43_HUMAN" 3 1756.8592 0.81 96984 8837 3 1756.864308 586.627 Probable splicing factor YJU2B OS=Homo sapiens OX=9606 GN=YJU2B PE=1 SV=2 4.25 1898.3 - 493212 - - - 2.9325 - 2.427 0.432 - 178.3 1 2 1 0.0052 15 0 0 0 2.58E+06 3.18E+06 - - - 5.6686 0.9999 221125_WJC_METTL3_EV_vs_WT_F07.08838.08838.3 2.47E-05 13/56 R.LETLGSASTSTPGRR.S "sp|Q96FF9|CDCA5_HUMAN,tr|B5MBX0|B5MBX0_HUMAN" 2 1531.7954 0.87 96985 8838 3 1531.797725 511.6058 Sororin OS=Homo sapiens OX=9606 GN=CDCA5 PE=1 SV=1 9.6 1898.4 - 345792 - - - 1.4956 - 2.609 0.464 - 213.3 1 2 0 0.0023 15 0 0 0 2.66E+06 3.05E+06 - - - 6.2148 0.9999 221125_WJC_METTL3_EV_vs_WT_F07.08839.08839.2 2.93E-05 13/28 K.AQAAAPASVPAQAPK[136.11].R "sp|P47914|RL29_HUMAN,tr|A0A3B3ITT5|A0A3B3ITT5_HUMAN" 2 1384.7554 0.8 96986 8839 2 1384.755057 693.385 60S ribosomal protein L29 OS=Homo sapiens OX=9606 GN=RPL29 PE=1 SV=2 8.8 1898.6 - 315751 - - - -0.2571 - 2.34 0.538 - 474.4 1 2 0 -0.0004 15 0 0 0 9.15E+07 1.14E+08 - - - 5.1047 0.9997 221125_WJC_METTL3_EV_vs_WT_F07.08840.08840.2 9.90E-06 26-Dec R.APVSIC[160.03]GGGENTSK.S sp|Q8NG27|PJA1_HUMAN 1 1375.6402 1.88 96987 8840 2 1375.64252 688.8274 E3 ubiquitin-protein ligase Praja-1 OS=Homo sapiens OX=9606 GN=PJA1 PE=1 SV=2 6.04 1898.7 - 312048 - - - 1.7018 - 1.848 0.514 - 457.1 1 2 0 0.0023 14 0 0 0 3.53E+06 1.88E+06 - - - 4.3777 0.9897 221125_WJC_METTL3_EV_vs_WT_F07.08841.08841.2 0.0018 20-Dec L.RGLDNTEFQGK.R "sp|Q9BWF3|RBM4_HUMAN,sp|Q9BQ04|RBM4B_HUMAN,tr|E9PB51|E9PB51_HUMAN" 3 1263.6208 1.79 96988 8841 2 1263.621383 632.8177 RNA-binding protein 4 OS=Homo sapiens OX=9606 GN=RBM4 PE=1 SV=1 6.07 1898.8 - 296819 - - - 0.4899 - 2.26 0.427 - 560.8 1 1 0 0.0006 11 0 0 0 5.27E+06 2.94E+06 - - - 4.4004 1 221125_WJC_METTL3_EV_vs_WT_F07.08843.08843.2 2.52E-08 24-Dec R.TAPGMGDQSGC[160.03]YR.C "sp|Q9BWF3|RBM4_HUMAN,sp|Q9BQ04|RBM4B_HUMAN,tr|E9PB51|E9PB51_HUMAN" 3 1398.5656 1.35 96990 8843 2 1398.566482 700.2901 RNA-binding protein 4 OS=Homo sapiens OX=9606 GN=RBM4 PE=1 SV=1 5.5 1899.1 - 253699 - - - 0.6063 - 2.092 0.704 - 413.5 1 2 0 0.0008 13 0 0 0 3.88E+06 2.87E+06 - - - 6.1349 0.9907 221125_WJC_METTL3_EV_vs_WT_F07.08844.08844.2 0.0332 14/20 L.R[166.11]GLDNTEFQGK[136.11].R "sp|Q9BWF3|RBM4_HUMAN,sp|Q9BQ04|RBM4B_HUMAN,tr|E9PB51|E9PB51_HUMAN" 3 1281.6432 1.79 96991 8844 2 1281.643941 641.8289 RNA-binding protein 4 OS=Homo sapiens OX=9606 GN=RBM4 PE=1 SV=1 6.07 1899.2 - 195462 - - - 0.5516 - 2.516 0.413 - 792.9 1 1 0 0.0007 11 0 0 0 5.27E+06 2.94E+06 - - - 4.5872 1 221125_WJC_METTL3_EV_vs_WT_F07.08845.08845.2 0.000625 15/24 K.TFQGHTNEVNAIK[136.11].W "sp|Q9BZK7|TBL1R_HUMAN,sp|O60907|TBL1X_HUMAN,sp|Q9BQ87|TBL1Y_HUMAN,tr|A0A1B0GVH3|A0A1B0GVH3_HUMAN,tr|A0A804HJZ5|A0A804HJZ5_HUMAN,tr|A0A2R8YFW3|A0A2R8YFW3_HUMAN,tr|A0A0D9SF63|A0A0D9SF63_HUMAN" 7 1465.7405 1.6 96992 8845 2 1465.738843 733.8775 F-box-like\WD repeat-containing protein TBL1XR1 OS=Homo sapiens OX=9606 GN=TBL1XR1 PE=1 SV=1 6.41 1899.3 - 184935 - - - -1.125 - 3.189 0.524 - 707.2 1 2 0 -0.0016 13 0 0 0 5.32E+06 3.32E+06 - - - 5.8872 0.9889 221125_WJC_METTL3_EV_vs_WT_F07.08851.08851.2 1.68E-06 22-Sep R.ENATNGVQQLSK.K sp|Q9P2D1|CHD7_HUMAN 1 1287.6419 1.42 96998 8851 2 1287.650804 644.8282 Chromodomain-helicase-DNA-binding protein 7 OS=Homo sapiens OX=9606 GN=CHD7 PE=1 SV=3 6.1 1900.1 - 81777.6 - - - 6.9204 - 2.048 0.461 - 185.6 1 2 0 0.0089 12 0 0 0 2.41E+07 1.70E+07 - - - 4.3293 0.9998 221125_WJC_METTL3_EV_vs_WT_F07.08854.08854.3 2.00E-05 15/44 K.QR[166.11]YPDGIISK[136.11]PK[136.11].N sp|Q86U44|MTA70_HUMAN 1 1426.8143 0.01 96999 8854 3 1426.814112 476.612 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 9.7 1900.6 - 1.61E+06 - - - -0.11 - 2.259 0.48 - 343.4 1 2 1 -0.0002 12 0 0 0 3.14E+05 4.71E+07 - - - 6.1503 1 221125_WJC_METTL3_EV_vs_WT_F07.08855.08855.2 2.32E-09 14/24 R.ASNGDAWVEAHGK.L "sp|P38646|GRP75_HUMAN,tr|H0Y8K0|H0Y8K0_HUMAN,tr|A0A7I2V2S7|A0A7I2V2S7_HUMAN,tr|A0A7I2V2G2|A0A7I2V2G2_HUMAN,tr|A0A3B3ITI4|A0A3B3ITI4_HUMAN,tr|A0A7I2V3F7|A0A7I2V3F7_HUMAN,tr|A0A7I2YQB2|A0A7I2YQB2_HUMAN,tr|D6RCD7|D6RCD7_HUMAN" 8 1340.6109 0.36 97000 8855 2 1340.610816 671.3127 "Stress-70 protein, mitochondrial OS=Homo sapiens OX=9606 GN=HSPA9 PE=1 SV=2" 5.32 1900.7 - 1.15E+06 - - - -0.0835 - 2.968 0.687 - 847.1 1 2 0 -0.0001 13 0 0 0 3.36E+07 9.25E+07 - - - 6.9072 0.9998 221125_WJC_METTL3_EV_vs_WT_F07.08856.08856.2 6.95E-05 15/28 K.AQAAAPASVPAQAPK.R "sp|P47914|RL29_HUMAN,tr|A0A3B3ITT5|A0A3B3ITT5_HUMAN" 2 1376.7412 0.8 97001 8856 2 1376.740629 689.3779 60S ribosomal protein L29 OS=Homo sapiens OX=9606 GN=RPL29 PE=1 SV=2 8.8 1900.8 - 799781 - - - -0.4242 - 2.595 0.381 - 554.5 1 2 0 -0.0006 15 0 0 0 9.15E+07 1.14E+08 - - - 4.1993 0.8598 221125_WJC_METTL3_EV_vs_WT_F07.08857.08857.3 0.00882 15/36 K.IKIIAPPERK.Y "sp|P63261|ACTG_HUMAN,sp|P68133|ACTS_HUMAN,sp|P62736|ACTA_HUMAN,sp|P68032|ACTC_HUMAN,sp|Q562R1|ACTBL_HUMAN,sp|P60709|ACTB_HUMAN,sp|P63267|ACTH_HUMAN,tr|A0A2R8YFE2|A0A2R8YFE2_HUMAN,tr|A0A804GS07|A0A804GS07_HUMAN,tr|A0A6Q8PFE4|A0A6Q8PFE4_HUMAN,tr|A0A804HKV3|A0A804HKV3_HUMAN,tr|I3L4N8|I3L4N8_HUMAN" 12 1163.739 0.99 97002 8857 3 1163.738462 388.9203 "Actin, cytoplasmic 2 OS=Homo sapiens OX=9606 GN=ACTG1 PE=1 SV=1" 9.99 1900.9 - 769224 - - - -0.4872 - 2.167 0.025 - 253.4 1 2 1 -0.0006 10 0 0 0 4.13E+06 4.17E+06 - - - 1.0771 1 221125_WJC_METTL3_EV_vs_WT_F07.08858.08858.2 3.81E-08 13/20 S.NGDAWVEAHGK[136.11].L "sp|P38646|GRP75_HUMAN,tr|H0Y8K0|H0Y8K0_HUMAN,tr|A0A7I2V2S7|A0A7I2V2S7_HUMAN,tr|A0A7I2V2G2|A0A7I2V2G2_HUMAN,tr|A0A3B3ITI4|A0A3B3ITI4_HUMAN,tr|A0A7I2V3F7|A0A7I2V3F7_HUMAN,tr|A0A7I2YQB2|A0A7I2YQB2_HUMAN,tr|D6RCD7|D6RCD7_HUMAN" 8 1190.556 1.2 97003 8858 2 1190.555303 596.2853 "Stress-70 protein, mitochondrial OS=Homo sapiens OX=9606 GN=HSPA9 PE=1 SV=2" 5.32 1901.1 - 764991 - - - -0.5728 - 2.582 0.617 - 899 1 1 0 -0.0007 11 0 0 0 2.72E+07 2.26E+07 - - - 6.164 1 221125_WJC_METTL3_EV_vs_WT_F07.08859.08859.2 1.55E-07 15/22 A.SNGDAWVEAHGK[136.11].L "sp|P38646|GRP75_HUMAN,tr|H0Y8K0|H0Y8K0_HUMAN,tr|A0A7I2V2S7|A0A7I2V2S7_HUMAN,tr|A0A7I2V2G2|A0A7I2V2G2_HUMAN,tr|A0A3B3ITI4|A0A3B3ITI4_HUMAN,tr|A0A7I2V3F7|A0A7I2V3F7_HUMAN,tr|A0A7I2YQB2|A0A7I2YQB2_HUMAN,tr|D6RCD7|D6RCD7_HUMAN" 8 1277.588 0.46 97004 8859 2 1277.585072 639.8013 "Stress-70 protein, mitochondrial OS=Homo sapiens OX=9606 GN=HSPA9 PE=1 SV=2" 5.3 1901.2 - 664877 - - - -2.3028 - 2.78 0.648 - 1167 1 1 0 -0.0029 12 0 0 0 9.54E+06 2.07E+07 - - - 6.5164 0.9852 221125_WJC_METTL3_EV_vs_WT_F07.08860.08860.3 0.0454 15/36 K.IK[136.11]IIAPPER[166.11]K[136.11].Y "sp|P63261|ACTG_HUMAN,sp|P68133|ACTS_HUMAN,sp|P62736|ACTA_HUMAN,sp|P68032|ACTC_HUMAN,sp|Q562R1|ACTBL_HUMAN,sp|P60709|ACTB_HUMAN,sp|P63267|ACTH_HUMAN,tr|A0A2R8YFE2|A0A2R8YFE2_HUMAN,tr|A0A804GS07|A0A804GS07_HUMAN,tr|A0A6Q8PFE4|A0A6Q8PFE4_HUMAN,tr|A0A804HKV3|A0A804HKV3_HUMAN,tr|I3L4N8|I3L4N8_HUMAN" 12 1189.7757 0.99 97005 8860 3 1189.776568 397.5992 "Actin, cytoplasmic 2 OS=Homo sapiens OX=9606 GN=ACTG1 PE=1 SV=1" 9.99 1901.3 - 650838 - - - 0.7304 - 2.011 0.173 - 302.2 1 2 1 0.0009 10 0 0 0 4.15E+06 4.17E+06 - - - 2.5089 0.9996 221125_WJC_METTL3_EV_vs_WT_F07.08866.08866.2 2.34E-06 22-Oct R.ENATNGVQQLSK[136.11].K sp|Q9P2D1|CHD7_HUMAN 1 1295.6561 1.43 97011 8866 2 1295.653662 648.8353 Chromodomain-helicase-DNA-binding protein 7 OS=Homo sapiens OX=9606 GN=CHD7 PE=1 SV=3 6.1 1902.1 - 332459 - - - -1.8763 - 1.83 0.485 - 215.2 1 2 0 -0.0024 12 0 0 0 2.41E+07 1.69E+07 - - - 4.2125 1 221125_WJC_METTL3_EV_vs_WT_F07.08871.08871.3 1.40E-05 Dec-48 K.TFQGHTNEVNAIK[136.11].W "sp|Q9BZK7|TBL1R_HUMAN,sp|O60907|TBL1X_HUMAN,sp|Q9BQ87|TBL1Y_HUMAN,tr|A0A1B0GVH3|A0A1B0GVH3_HUMAN,tr|A0A804HJZ5|A0A804HJZ5_HUMAN,tr|A0A2R8YFW3|A0A2R8YFW3_HUMAN,tr|A0A0D9SF63|A0A0D9SF63_HUMAN" 7 1465.7405 1.75 97015 8871 3 1465.740601 489.5874 F-box-like\WD repeat-containing protein TBL1XR1 OS=Homo sapiens OX=9606 GN=TBL1XR1 PE=1 SV=1 6.41 1902.7 - 5.09E+06 - - - 0.0744 - 1.95 0.498 - 112.1 1 2 0 0.0001 13 0 0 0 8.24E+07 4.71E+07 - - - 5.9029 0.9982 221125_WJC_METTL3_EV_vs_WT_F07.08876.08876.2 0.000153 20-Dec R.VR[166.11]EEEIEVDSR[166.11].V "sp|Q14978|NOLC1_HUMAN,tr|A0A0A0MRM9|A0A0A0MRM9_HUMAN" 2 1379.6796 3.18 97020 8876 2 1379.679111 690.8471 Nucleolar and coiled-body phosphoprotein 1 OS=Homo sapiens OX=9606 GN=NOLC1 PE=1 SV=2 4.25 1903 - 1.95E+06 - - - -0.3276 - 2.107 0.45 - 297.7 1 2 1 -0.0005 11 0 0 0 1.00E+08 3.15E+07 - - - 4.3807 0.9998 221125_WJC_METTL3_EV_vs_WT_F07.08878.08878.2 3.21E-05 16-Oct K.SFQQSSLSR.D "sp|P43243|MATR3_HUMAN,tr|A0A1B0GX04|A0A1B0GX04_HUMAN,tr|D6RBS2|D6RBS2_HUMAN,tr|A8MXP9|A8MXP9_HUMAN,tr|D6R991|D6R991_HUMAN,tr|D6REK4|D6REK4_HUMAN,tr|D6R9F3|D6R9F3_HUMAN,tr|A0A0R4J2E8|A0A0R4J2E8_HUMAN,tr|D6RB45|D6RB45_HUMAN,tr|D6RCM3|D6RCM3_HUMAN,tr|D6R8Z5|D6R8Z5_HUMAN,tr|D6REM6|D6REM6_HUMAN" 12 1038.5094 1 97022 8878 2 1038.508589 520.262 Matrin-3 OS=Homo sapiens OX=9606 GN=MATR3 PE=1 SV=2 9.47 1903.2 - 942503 - - - -0.8031 - 1.695 0.455 - 379.8 1 2 0 -0.0008 9 0 0 0 1.97E+07 1.98E+07 - - - 3.928 0.9997 221125_WJC_METTL3_EV_vs_WT_F07.08880.08880.2 0.00111 16-Sep K.SFQQSSLSR[166.11].D "sp|P43243|MATR3_HUMAN,tr|A0A1B0GX04|A0A1B0GX04_HUMAN,tr|D6RBS2|D6RBS2_HUMAN,tr|A8MXP9|A8MXP9_HUMAN,tr|D6R991|D6R991_HUMAN,tr|D6REK4|D6REK4_HUMAN,tr|D6R9F3|D6R9F3_HUMAN,tr|A0A0R4J2E8|A0A0R4J2E8_HUMAN,tr|D6RB45|D6RB45_HUMAN,tr|D6RCM3|D6RCM3_HUMAN,tr|D6R8Z5|D6R8Z5_HUMAN,tr|D6REM6|D6REM6_HUMAN" 12 1048.5177 0.97 97024 8880 2 1048.517378 525.2661 Matrin-3 OS=Homo sapiens OX=9606 GN=MATR3 PE=1 SV=2 9.47 1903.4 - 769928 - - - -0.3004 - 1.483 0.475 - 310.9 1 2 0 -0.0003 9 0 0 0 1.97E+07 2.04E+07 - - - 3.6893 0.9933 221125_WJC_METTL3_EV_vs_WT_F07.08882.08882.2 0.000392 13/22 A.SNGDAWVEAHGK.L "sp|P38646|GRP75_HUMAN,tr|H0Y8K0|H0Y8K0_HUMAN,tr|A0A7I2V2S7|A0A7I2V2S7_HUMAN,tr|A0A7I2V2G2|A0A7I2V2G2_HUMAN,tr|A0A3B3ITI4|A0A3B3ITI4_HUMAN,tr|A0A7I2V3F7|A0A7I2V3F7_HUMAN,tr|A0A7I2YQB2|A0A7I2YQB2_HUMAN,tr|D6RCD7|D6RCD7_HUMAN" 8 1269.5738 0.46 97026 8882 2 1269.572357 635.7942 "Stress-70 protein, mitochondrial OS=Homo sapiens OX=9606 GN=HSPA9 PE=1 SV=2" 5.3 1903.7 - 484428 - - - -1.1476 - 2.565 0.541 - 818.5 1 1 0 -0.0015 12 0 0 0 9.54E+06 2.07E+07 - - - 5.5148 1 221125_WJC_METTL3_EV_vs_WT_F07.08888.08888.3 1.36E-07 13/40 K.GIPHLVTHDAR.T "sp|P62701|RS4X_HUMAN,sp|P22090|RS4Y1_HUMAN,sp|Q8TD47|RS4Y2_HUMAN,tr|C9JEH7|C9JEH7_HUMAN" 4 1214.652 0.96 97030 8888 3 1214.65054 405.8913 "40S ribosomal protein S4, X isoform OS=Homo sapiens OX=9606 GN=RPS4X PE=1 SV=2" 6.92 1904.3 - 4.02E+06 - - - -1.2053 - 2.512 0.439 - 277.6 1 2 0 -0.0015 11 0 0 0 4.24E+08 4.43E+08 - - - 6.0506 0.99 221125_WJC_METTL3_EV_vs_WT_F07.08891.08891.3 0.23 Sep-56 K.ALQDSAPDRPSPVER.L "sp|Q9H9B1|EHMT1_HUMAN,tr|A0A1B0GWF6|A0A1B0GWF6_HUMAN,tr|A0A0C4DGF8|A0A0C4DGF8_HUMAN,tr|A0A1B0GU48|A0A1B0GU48_HUMAN,tr|A0A1B0GV09|A0A1B0GV09_HUMAN" 5 1636.8169 0.91 97033 8891 3 1636.816488 546.6129 Histone-lysine N-methyltransferase EHMT1 OS=Homo sapiens OX=9606 GN=EHMT1 PE=1 SV=4 4.56 1904.7 - 746551 - - - -0.2505 - 1.58 0.186 - 94.8 1 2 0 -0.0004 15 0 0 0 7.00E+06 7.72E+06 - - - 1.8072 0.9764 221125_WJC_METTL3_EV_vs_WT_F07.08892.08892.3 0.0562 Oct-36 R.DK[136.11]DGTQVDFR[166.11].G "sp|P78332|RBM6_HUMAN,tr|F8WCA5|F8WCA5_HUMAN,tr|E9PGM9|E9PGM9_HUMAN" 3 1197.5745 1.75 97034 8892 3 1197.570945 400.1988 RNA-binding protein 6 OS=Homo sapiens OX=9606 GN=RBM6 PE=1 SV=5 4.43 1904.9 - 737842 - - - -2.9568 - 1.685 0.268 - 149.7 1 2 1 -0.0035 10 0 0 0 1.87E+07 1.07E+07 - - - 3.0507 0.9782 221125_WJC_METTL3_EV_vs_WT_F07.08893.08893.2 6.22E-05 18-Nov N.GDAWVEAHGK[136.11].L "sp|P38646|GRP75_HUMAN,tr|H0Y8K0|H0Y8K0_HUMAN,tr|A0A7I2V2S7|A0A7I2V2S7_HUMAN,tr|A0A7I2V2G2|A0A7I2V2G2_HUMAN,tr|A0A3B3ITI4|A0A3B3ITI4_HUMAN,tr|A0A7I2V3F7|A0A7I2V3F7_HUMAN,tr|A0A7I2YQB2|A0A7I2YQB2_HUMAN,tr|D6RCD7|D6RCD7_HUMAN" 8 1076.5131 0.27 97035 8893 2 1076.510773 539.2638 "Stress-70 protein, mitochondrial OS=Homo sapiens OX=9606 GN=HSPA9 PE=1 SV=2" 5.32 1905 - 586257 - - - -2.1226 - 1.863 0.494 - 424.6 1 1 0 -0.0023 10 0 0 0 2.19E+06 8.21E+06 - - - 4.4257 0.9961 221125_WJC_METTL3_EV_vs_WT_F07.08902.08902.3 0.0216 Sep-36 R.DREEALHQFR.S "sp|O00571|DDX3X_HUMAN,sp|O15523|DDX3Y_HUMAN,tr|A0A2R8YFR4|A0A2R8YFR4_HUMAN,tr|A0A2R8YCW1|A0A2R8YCW1_HUMAN,tr|A0A2R8YDH3|A0A2R8YDH3_HUMAN,tr|A0A2R8YDT5|A0A2R8YDT5_HUMAN,tr|A0A2R8Y645|A0A2R8Y645_HUMAN,tr|A0A2R8YF78|A0A2R8YF78_HUMAN,tr|A0A0D9SFB3|A0A0D9SFB3_HUMAN,tr|A0A2R8YFS5|A0A2R8YFS5_HUMAN,tr|A0A0D9SF53|A0A0D9SF53_HUMAN,tr|A0A087WVZ1|A0A087WVZ1_HUMAN,tr|A0A0J9YVQ7|A0A0J9YVQ7_HUMAN,tr|A0A2R8Y5G6|A0A2R8Y5G6_HUMAN,tr|A0A2R8Y7T2|A0A2R8Y7T2_HUMAN,tr|A0A0D9SG12|A0A0D9SG12_HUMAN,tr|F6S8Q4|F6S8Q4_HUMAN,tr|A0A2U3TZJ9|A0A2U3TZJ9_HUMAN,tr|A0A2R8Y4A4|A0A2R8Y4A4_HUMAN" 19 1299.632 1.34 97042 8902 3 1299.631051 434.2179 ATP-dependent RNA helicase DDX3X OS=Homo sapiens OX=9606 GN=DDX3X PE=1 SV=3 5.45 1905.9 - 1.77E+06 - - - -0.7279 - 1.772 0.289 - 110.1 1 2 1 -0.0009 10 0 0 0 2.00E+07 1.49E+07 - - - 3.4326 0.9958 221125_WJC_METTL3_EV_vs_WT_F07.08903.08903.3 0.00175 Oct-36 R.TEVSQWEK[136.11]PK[136.11].E "sp|Q9BTA9|WAC_HUMAN,tr|A0A494C0B7|A0A494C0B7_HUMAN,tr|A0A0A0MRT2|A0A0A0MRT2_HUMAN,tr|A0A494C0C1|A0A494C0C1_HUMAN,tr|A0A494C0S5|A0A494C0S5_HUMAN,tr|A0A0A0MSR1|A0A0A0MSR1_HUMAN,tr|J3QTA0|J3QTA0_HUMAN,tr|C9JVK6|C9JVK6_HUMAN" 8 1246.6529 20.81 97043 8903 3 1246.647692 416.5582 WW domain-containing adapter protein with coiled-coil OS=Homo sapiens OX=9606 GN=WAC PE=1 SV=3 5.81 1906 - 896069 - - - -4.1391 - 2.021 0.292 - 221.3 1 2 0 -0.0052 10 0 0 0 2.79E+08 1.34E+07 - - - 3.8489 1 221125_WJC_METTL3_EV_vs_WT_F07.08911.08911.2 1.55E-06 14/24 K.TLSNSSQSELENR[166.11].L "sp|Q8TBA6|GOGA5_HUMAN,tr|H0YK03|H0YK03_HUMAN" 2 1473.6935 1.77 97049 8911 2 1473.6923 737.854 Golgin subfamily A member 5 OS=Homo sapiens OX=9606 GN=GOLGA5 PE=1 SV=3 4.53 1906.9 - 851140 - - - -0.8041 - 2.66 0.627 - 521.4 1 2 0 -0.0012 13 0 0 0 4.63E+07 2.62E+07 - - - 6.1826 0.9994 221125_WJC_METTL3_EV_vs_WT_F07.08912.08912.3 0.001 Dec-40 K.VSNRFSGVPDR.F "sp|A0A075B6R9|KVD24_HUMAN,sp|A0A075B6S2|KVD29_HUMAN,sp|A0A0A0MRZ7|KVD26_HUMAN" 3 1232.6262 79.48 97050 8912 3 1232.624327 411.8827 Probable non-functional immunoglobulin kappa variable 2D-24 OS=Homo sapiens OX=9606 GN=IGKV2D-24 PE=1 SV=1 9.57 1906.9 - 3.65E+06 - - - -1.5065 - 2.155 0.402 - 215.3 1 2 1 -0.0019 11 0 0 0 4.55E+08 5.72E+06 - - - 5.2026 0.9964 221125_WJC_METTL3_EV_vs_WT_F07.08913.08913.3 0.00768 Nov-40 K.NIQVSHQEFSK.M sp|Q8WUM4|PDC6I_HUMAN 1 1315.6521 1.09 97051 8913 3 1315.652807 439.558 Programmed cell death 6-interacting protein OS=Homo sapiens OX=9606 GN=PDCD6IP PE=1 SV=1 6.75 1907 - 2.44E+06 - - - 0.5647 - 1.7 0.215 - 164.1 1 2 0 0.0007 11 0 0 0 3.42E+07 3.13E+07 - - - 2.4443 1 221125_WJC_METTL3_EV_vs_WT_F07.08916.08916.2 1.42E-07 14/24 K.TLSNSSQSELENR.L "sp|Q8TBA6|GOGA5_HUMAN,tr|H0YK03|H0YK03_HUMAN" 2 1463.6852 1.77 97054 8916 2 1463.683098 732.8499 Golgin subfamily A member 5 OS=Homo sapiens OX=9606 GN=GOLGA5 PE=1 SV=3 4.53 1907.3 - 1.53E+06 - - - -1.4463 - 2.641 0.623 - 524.2 1 2 0 -0.0021 13 0 0 0 4.63E+07 2.62E+07 - - - 6.1343 0.9789 221125_WJC_METTL3_EV_vs_WT_F07.08917.08917.3 0.222 Nov-40 K.TQHNGMNNIIR[166.11].L sp|Q7Z6Z7|HUWE1_HUMAN 1 1306.644 0.92 97055 8917 3 1306.639604 436.5553 E3 ubiquitin-protein ligase HUWE1 OS=Homo sapiens OX=9606 GN=HUWE1 PE=1 SV=3 9.44 1907.4 - 478758 - - - -3.3429 - 1.846 0.182 - 156.9 1 2 0 -0.0044 11 0 0 0 1.45E+07 1.58E+07 - - - 2.3094 0.9994 221125_WJC_METTL3_EV_vs_WT_F07.08923.08923.3 1.51E-05 Dec-40 K.TKDGVVEITGK.H "sp|P04792|HSPB1_HUMAN,tr|A0A6Q8PHJ6|A0A6Q8PHJ6_HUMAN,tr|A0A6Q8PFK8|A0A6Q8PFK8_HUMAN" 3 1145.6292 11.27 97059 8923 3 1145.627233 382.8837 Heat shock protein beta-1 OS=Homo sapiens OX=9606 GN=HSPB1 PE=1 SV=2 5.73 1908 - 620271 - - - -1.7196 - 2.471 0.382 - 195.7 1 2 1 -0.002 11 0 0 0 1.91E+07 1.69E+06 - - - 5.3683 0.9831 221125_WJC_METTL3_EV_vs_WT_F07.08927.08927.3 5.14E-07 14/68 S.LVSGLNSSASEPAK[136.11]EPAK[136.11].K "sp|Q86U44|MTA70_HUMAN,tr|F5H6D8|F5H6D8_HUMAN,tr|H0YFV6|H0YFV6_HUMAN,tr|B4DTN4|B4DTN4_HUMAN" 4 1799.96 0 97061 8927 3 1799.955464 600.9939 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 6.14 1908.5 - 4.23E+06 - - - -2.5162 - 2.598 0.607 - 131.3 1 1 1 -0.0045 18 0 0 0 7.96E+04 9.13E+07 - - - 7.6836 0.8731 221125_WJC_METTL3_EV_vs_WT_F07.08928.08928.2 0.000731 18-Nov V.SNRFSGVPDR.F "sp|A0A075B6R9|KVD24_HUMAN,sp|A0A0C4DH68|KV224_HUMAN,sp|A0A075B6S2|KVD29_HUMAN,sp|A0A0A0MRZ7|KVD26_HUMAN" 4 1133.5578 999 97062 8928 2 1133.557533 567.7862 Probable non-functional immunoglobulin kappa variable 2D-24 OS=Homo sapiens OX=9606 GN=IGKV2D-24 PE=1 SV=1 9.31 1908.6 - 1.03E+06 - - - -0.2091 - 1.974 0.411 - 235.5 1 1 1 -0.0002 10 0 0 0 3.34E+07 0.00E+00 - - - 3.9748 0.985 221125_WJC_METTL3_EV_vs_WT_F07.08930.08930.3 0.0602 Sep-36 R.SEHNLVNIQK.T "sp|Q96ES7|SGF29_HUMAN,tr|H3BPL5|H3BPL5_HUMAN" 2 1180.62 1.19 97064 8930 3 1180.617954 394.5473 SAGA-associated factor 29 OS=Homo sapiens OX=9606 GN=SGF29 PE=1 SV=1 6.47 1908.8 - 877931 - - - -1.7635 - 1.533 0.182 - 125.1 1 2 0 -0.0021 10 0 0 0 3.75E+07 3.14E+07 - - - 1.8162 0.996 221125_WJC_METTL3_EV_vs_WT_F07.08931.08931.3 0.0277 Oct-36 R.SEHNLVNIQK[136.11].T "sp|Q96ES7|SGF29_HUMAN,tr|H3BPL5|H3BPL5_HUMAN" 2 1188.6342 1.19 97065 8931 3 1188.633498 397.2187 SAGA-associated factor 29 OS=Homo sapiens OX=9606 GN=SGF29 PE=1 SV=1 6.47 1908.9 - 840276 - - - -0.6209 - 1.789 0.191 - 144.8 1 2 0 -0.0007 10 0 0 0 3.75E+07 3.14E+07 - - - 2.3679 0.9997 221125_WJC_METTL3_EV_vs_WT_F07.08937.08937.3 8.54E-05 16/48 K.IEQVDKEDEITEK.K sp|Q9Y2X3|NOP58_HUMAN 1 1574.7675 0.83 97069 8937 3 1574.76709 525.9298 Nucleolar protein 58 OS=Homo sapiens OX=9606 GN=NOP58 PE=1 SV=1 4.08 1909.7 - 1.33E+06 - - - -0.2902 - 2.525 0.426 - 337.5 1 2 1 -0.0005 13 0 0 0 1.34E+07 1.62E+07 - - - 5.8007 0.994 221125_WJC_METTL3_EV_vs_WT_F07.08938.08938.2 0.0176 20-Sep K.VSNRFSGVPDR.F "sp|A0A075B6R9|KVD24_HUMAN,sp|A0A075B6S2|KVD29_HUMAN,sp|A0A0A0MRZ7|KVD26_HUMAN" 3 1232.6262 5.76 97070 8938 2 1232.625882 617.3204 Probable non-functional immunoglobulin kappa variable 2D-24 OS=Homo sapiens OX=9606 GN=IGKV2D-24 PE=1 SV=1 9.57 1909.8 - 2.10E+06 - - - -0.245 - 1.87 0.299 - 100.4 1 2 1 -0.0003 11 0 0 0 4.06E+07 7.05E+06 - - - 2.9426 0.9999 221125_WJC_METTL3_EV_vs_WT_F07.08940.08940.3 5.95E-08 18/48 K.IEQVDK[136.11]EDEITEK[136.11].K sp|Q9Y2X3|NOP58_HUMAN 1 1590.7959 0.83 97072 8940 3 1590.79422 531.2726 Nucleolar protein 58 OS=Homo sapiens OX=9606 GN=NOP58 PE=1 SV=1 4.08 1910 - 915845 - - - -1.0856 - 3.115 0.436 - 577.4 1 2 1 -0.0017 13 0 0 0 1.34E+07 1.62E+07 - - - 6.4811 0.9948 221125_WJC_METTL3_EV_vs_WT_F07.08942.08942.3 0.0219 Aug-36 K.R[166.11]FPGYDSESK[136.11].E "sp|P46777|RL5_HUMAN,tr|A0A2R8Y6J3|A0A2R8Y6J3_HUMAN" 2 1202.5687 0.81 97074 8942 3 1202.567249 401.8635 60S ribosomal protein L5 OS=Homo sapiens OX=9606 GN=RPL5 PE=1 SV=3 6.07 1910.2 - 659292 - - - -1.1833 - 1.402 0.246 - 81.9 1 2 0 -0.0014 10 0 0 0 1.36E+07 1.68E+07 - - - 2.2691 0.976 221125_WJC_METTL3_EV_vs_WT_F07.08943.08943.2 0.172 20-Jul K.NIQVSHQEFSK[136.11].M sp|Q8WUM4|PDC6I_HUMAN 1 1323.6663 1.39 97075 8943 2 1323.661565 662.8404 Programmed cell death 6-interacting protein OS=Homo sapiens OX=9606 GN=PDCD6IP PE=1 SV=1 6.75 1910.3 - 462497 - - - -3.55 - 1.537 0.153 - 121.6 1 2 0 -0.0047 11 0 0 0 6.14E+06 4.43E+06 - - - 1.3324 0.9998 221125_WJC_METTL3_EV_vs_WT_F07.08947.08947.2 1.85E-06 13/20 K.GIPHLVTHDAR.T "sp|P62701|RS4X_HUMAN,sp|P22090|RS4Y1_HUMAN,sp|Q8TD47|RS4Y2_HUMAN,tr|C9JEH7|C9JEH7_HUMAN" 4 1214.652 1.01 97077 8947 2 1214.650544 608.3333 "40S ribosomal protein S4, X isoform OS=Homo sapiens OX=9606 GN=RPS4X PE=1 SV=2" 6.92 1910.9 - 1.34E+06 - - - -1.202 - 1.919 0.543 - 599.2 1 2 0 -0.0015 11 0 0 0 3.42E+07 3.40E+07 - - - 4.8144 0.9871 221125_WJC_METTL3_EV_vs_WT_F07.08948.08948.2 3.26E-06 16-Oct L.PHLVTHDAR.T "sp|P62701|RS4X_HUMAN,sp|P22090|RS4Y1_HUMAN,sp|Q8TD47|RS4Y2_HUMAN,tr|C9JEH7|C9JEH7_HUMAN" 4 1044.5465 0.93 97078 8948 2 1044.544237 523.2805 "40S ribosomal protein S4, X isoform OS=Homo sapiens OX=9606 GN=RPS4X PE=1 SV=2" 7.33 1911 - 894915 - - - -2.1445 - 2.313 0.537 - 493.5 1 1 0 -0.0022 9 0 0 0 1.97E+07 2.11E+07 - - - 5.4325 0.9994 221125_WJC_METTL3_EV_vs_WT_F07.08949.08949.3 0.00189 14/36 K.EEVKLETHIR.V sp|Q9NZI8|IF2B1_HUMAN 1 1252.6776 1.41 97079 8949 3 1252.679715 418.5665 Insulin-like growth factor 2 mRNA-binding protein 1 OS=Homo sapiens OX=9606 GN=IGF2BP1 PE=1 SV=2 5.5 1911.1 - 2.07E+06 - - - 1.7275 - 2.553 0.375 - 348.7 1 2 1 0.0022 10 0 0 0 5.09E+07 3.62E+07 - - - 5.4575 0.9999 221125_WJC_METTL3_EV_vs_WT_F07.08952.08952.2 3.31E-09 22-Dec K.GTDDSMTLQSQK.F "sp|O00422|SAP18_HUMAN,tr|H7BZW6|H7BZW6_HUMAN" 2 1309.582 1.55 97082 8952 2 1309.582074 655.7983 Histone deacetylase complex subunit SAP18 OS=Homo sapiens OX=9606 GN=SAP18 PE=1 SV=1 4.21 1911.4 - 656686 - - - 0.0603 - 2.515 0.465 - 727.8 1 2 0 0.0001 12 0 0 0 1.04E+07 6.68E+06 - - - 4.9021 0.999 221125_WJC_METTL3_EV_vs_WT_F07.08958.08958.3 0.00242 Oct-36 K.EEVK[136.11]LETHIR[166.11].V sp|Q9NZI8|IF2B1_HUMAN 1 1270.7 1.41 97086 8958 3 1270.699111 424.574 Insulin-like growth factor 2 mRNA-binding protein 1 OS=Homo sapiens OX=9606 GN=IGF2BP1 PE=1 SV=2 5.5 1912.2 - 2.83E+06 - - - -0.7161 - 2.334 0.313 - 180.3 1 2 1 -0.0009 10 0 0 0 5.09E+07 3.61E+07 - - - 4.5047 1 221125_WJC_METTL3_EV_vs_WT_F07.08959.08959.3 1.95E-09 17/52 K.YLANIEQQHGNSGR.N sp|Q9UKX7|NUP50_HUMAN 1 1585.7597 1.43 97087 8959 3 1585.759262 529.5938 Nuclear pore complex protein Nup50 OS=Homo sapiens OX=9606 GN=NUP50 PE=1 SV=2 6.75 1912.3 - 1.88E+06 - - - -0.2869 - 3.001 0.648 - 299.4 1 2 0 -0.0005 14 0 0 0 4.06E+07 2.84E+07 - - - 8.6849 0.9999 221125_WJC_METTL3_EV_vs_WT_F07.08960.08960.3 5.06E-05 14/52 K.YLANIEQQHGNSGR[166.11].N sp|Q9UKX7|NUP50_HUMAN 1 1595.768 1.43 97088 8960 3 1595.765439 532.9299 Nuclear pore complex protein Nup50 OS=Homo sapiens OX=9606 GN=NUP50 PE=1 SV=2 6.75 1912.3 - 1.51E+06 - - - -1.5967 - 2.15 0.486 - 154.3 1 2 0 -0.0025 14 0 0 0 4.06E+07 2.84E+07 - - - 5.992 0.9998 221125_WJC_METTL3_EV_vs_WT_F07.08961.08961.2 3.36E-07 15/20 R.HQVEQLSSSLK[136.11].Q "sp|Q14980|NUMA1_HUMAN,tr|A0A087WY61|A0A087WY61_HUMAN,tr|F5H4J1|F5H4J1_HUMAN,tr|F5H6Y5|F5H6Y5_HUMAN" 4 1262.671 0.84 97089 8961 2 1262.672427 632.3428 Nuclear mitotic apparatus protein 1 OS=Homo sapiens OX=9606 GN=NUMA1 PE=1 SV=2 6.75 1912.5 - 668951 - - - 1.1183 - 2.596 0.432 - 532.4 1 2 0 0.0014 11 0 0 0 8.46E+06 1.00E+07 - - - 4.812 0.9999 221125_WJC_METTL3_EV_vs_WT_F07.08969.08969.3 0.00802 17/44 K.VTARPSQPPLPR.R "sp|Q9ULV3|CIZ1_HUMAN,tr|Q5SYW2|Q5SYW2_HUMAN,tr|F5H2X7|F5H2X7_HUMAN,tr|H0Y5D5|H0Y5D5_HUMAN,tr|Q9BTG3|Q9BTG3_HUMAN" 5 1317.7517 3.1 97095 8969 3 1317.751611 440.2578 Cip1-interacting zinc finger protein OS=Homo sapiens OX=9606 GN=CIZ1 PE=1 SV=2 12 1913.4 - 2.44E+06 - - - -0.082 - 2.897 0.392 - 625.1 1 2 0 -0.0001 12 0 0 0 5.80E+07 1.87E+07 - - - 5.8587 0.9852 221125_WJC_METTL3_EV_vs_WT_F07.08972.08972.2 0.0168 20-Oct L.TNFNSAHDTDR.N "sp|Q08188|TGM3_HUMAN,tr|A0A494C0J7|A0A494C0J7_HUMAN" 2 1276.5432 4.19 97098 8972 2 1276.540969 639.2789 Protein-glutamine gamma-glutamyltransferase E OS=Homo sapiens OX=9606 GN=TGM3 PE=1 SV=4 5.18 1913.7 - 598425 - - - -1.7806 - 2.234 0.468 - 442.3 1 1 0 -0.0023 11 0 0 0 7.13E+06 1.70E+06 - - - 4.6714 0.9995 221125_WJC_METTL3_EV_vs_WT_F07.08974.08974.2 0.0017 18-Sep R.GPLPLSSQHR[166.11].G "sp|P43243|MATR3_HUMAN,tr|A8MXP9|A8MXP9_HUMAN,tr|D6R991|D6R991_HUMAN,tr|A0A0R4J2E8|A0A0R4J2E8_HUMAN,tr|D6R8Z5|D6R8Z5_HUMAN,tr|D6REM6|D6REM6_HUMAN" 6 1100.5966 1.49 97100 8974 2 1100.594802 551.3056 Matrin-3 OS=Homo sapiens OX=9606 GN=MATR3 PE=1 SV=2 9.76 1913.9 - 435352 - - - -1.6446 - 1.751 0.402 - 300.6 1 2 0 -0.0018 10 0 0 0 1.65E+07 1.11E+07 - - - 3.5733 0.9972 221125_WJC_METTL3_EV_vs_WT_F07.08975.08975.2 0.198 16-Aug K.KSSETLTFK.R "sp|Q9NPF5|DMAP1_HUMAN,tr|Q5TG39|Q5TG39_HUMAN,tr|Q5TG38|Q5TG38_HUMAN,tr|Q5TG40|Q5TG40_HUMAN,tr|Q5TG36|Q5TG36_HUMAN,tr|Q5TG37|Q5TG37_HUMAN" 6 1039.555 4.57 97101 8975 2 1039.553707 520.7848 DNA methyltransferase 1-associated protein 1 OS=Homo sapiens OX=9606 GN=DMAP1 PE=1 SV=1 8.59 1914 - 353061 - - - -1.2207 - 1.439 0.225 - 156.3 1 2 0 -0.0013 9 0 0 0 4.90E+06 1.07E+06 - - - 1.7554 0.9999 221125_WJC_METTL3_EV_vs_WT_F07.08980.08980.3 1.18E-05 28-Oct K.K[136.11]PFEEHWR[166.11].K "sp|P31040|SDHA_HUMAN,tr|A0A087X1I3|A0A087X1I3_HUMAN,tr|D6RFM5|D6RFM5_HUMAN" 3 1145.5737 0.001 97104 8980 3 1145.573661 382.8652 "Succinate dehydrogenase [ubiquinone] flavoprotein subunit, mitochondrial OS=Homo sapiens OX=9606 GN=SDHA PE=1 SV=2" 6.76 1914.6 - 827105 - - - -0.0323 - 2.112 0.416 - 151.9 1 2 0 0 8 0 0 0 0.00E+00 1.33E+07 - - - 5.5147 0.985 221125_WJC_METTL3_EV_vs_WT_F07.08991.08991.2 0.000453 14-Oct P.HLVTHDAR.T "sp|P62701|RS4X_HUMAN,sp|P22090|RS4Y1_HUMAN,sp|Q8TD47|RS4Y2_HUMAN,tr|C9JEH7|C9JEH7_HUMAN" 4 947.4937 0.85 97113 8991 2 947.49444 474.7541 "40S ribosomal protein S4, X isoform OS=Homo sapiens OX=9606 GN=RPS4X PE=1 SV=2" 6.92 1916.1 - 1.38E+06 - - - 0.7673 - 1.886 0.413 - 418.3 1 1 0 0.0007 8 0 0 0 1.91E+07 2.26E+07 - - - 4.0047 0.7643 221125_WJC_METTL3_EV_vs_WT_F07.08992.08992.2 0.00923 24-Sep R.NPQQHLNAQPQVT.M "sp|P11940|PABP1_HUMAN,tr|H0YAS6|H0YAS6_HUMAN,tr|H0YB75|H0YB75_HUMAN,tr|H0YAS7|H0YAS7_HUMAN,tr|A0A7I2YQE4|A0A7I2YQE4_HUMAN,tr|H0YAW6|H0YAW6_HUMAN,tr|A0A7I2V649|A0A7I2V649_HUMAN,tr|H0YAR2|H0YAR2_HUMAN,tr|E7ERJ7|E7ERJ7_HUMAN,tr|A0A7I2YQ88|A0A7I2YQ88_HUMAN,tr|A0A087WTT1|A0A087WTT1_HUMAN,tr|A0A7I2YQ90|A0A7I2YQ90_HUMAN,tr|A0A7I2V4N4|A0A7I2V4N4_HUMAN,tr|E7EQV3|E7EQV3_HUMAN" 14 1473.7324 - 97114 8992 2 1473.738026 737.8735 Polyadenylate-binding protein 1 OS=Homo sapiens OX=9606 GN=PABPC1 PE=1 SV=2 6.74 1916.2 - 600173 - - - 3.7904 - 1.609 0.344 - 150.6 1 1 0 0.0056 13 0 0 0 - - - - - 2.8007 0.9994 221125_WJC_METTL3_EV_vs_WT_F07.08994.08994.3 0.00392 Nov-52 K.NIVQHTTDSSLEEK[136.11].Q sp|Q9H501|ESF1_HUMAN 1 1607.7882 1.57 97116 8994 3 1607.790295 536.9367 ESF1 homolog OS=Homo sapiens OX=9606 GN=ESF1 PE=1 SV=1 4.65 1916.4 - 314960 - - - 1.2844 - 1.792 0.335 - 110 1 2 0 0.0021 14 0 0 0 2.15E+07 1.37E+07 - - - 3.8246 0.9989 221125_WJC_METTL3_EV_vs_WT_F07.08997.08997.2 0.00204 24-Nov K.NLIHGSDSVESAR.R "sp|Q13232|NDK3_HUMAN,tr|H3BPR2|H3BPR2_HUMAN" 2 1383.6743 1.77 97119 8997 2 1383.678366 692.8444 Nucleoside diphosphate kinase 3 OS=Homo sapiens OX=9606 GN=NME3 PE=1 SV=2 5.32 1916.8 - 258596 - - - 2.9704 - 1.974 0.411 - 417.5 1 2 0 0.0041 13 0 0 0 2.78E+06 1.57E+06 - - - 3.8208 0.9852 221125_WJC_METTL3_EV_vs_WT_F07.08999.08999.2 0.0247 24-Sep R.R[166.11]GDIIGVQGNPGK[136.11].T "sp|Q15046|SYK_HUMAN,tr|H3BVA8|H3BVA8_HUMAN,tr|J3KRL2|J3KRL2_HUMAN,tr|H3BPV7|H3BPV7_HUMAN" 4 1327.7327 0.7 97121 8999 2 1327.727249 664.8736 Lysine--tRNA ligase OS=Homo sapiens OX=9606 GN=KARS1 PE=1 SV=3 8.75 1917.1 - 303534 - - - -4.1191 - 1.675 0.227 - 173.9 1 2 0 -0.0055 13 0 0 0 3.59E+06 5.13E+06 - - - 2.0398 0.9993 221125_WJC_METTL3_EV_vs_WT_F07.09004.09004.3 0.002 Sep-36 R.GYDDRDYYSR.S "sp|P62995|TRA2B_HUMAN,tr|H7BXF3|H7BXF3_HUMAN,tr|H7C2L4|H7C2L4_HUMAN" 3 1308.5371 1.56 97124 9004 3 1308.53697 437.1863 Transformer-2 protein homolog beta OS=Homo sapiens OX=9606 GN=TRA2B PE=1 SV=1 4.43 1917.7 - 1.21E+06 - - - -0.0948 - 1.432 0.467 - 114.2 1 2 1 -0.0001 10 0 0 0 6.97E+07 4.47E+07 - - - 4.7952 1 221125_WJC_METTL3_EV_vs_WT_F07.09006.09006.2 3.98E-09 13/24 R.VITNFNSAHDTDR.N "sp|Q08188|TGM3_HUMAN,tr|A0A494C0J7|A0A494C0J7_HUMAN" 2 1488.6957 24.78 97126 9006 2 1488.697824 745.3551 Protein-glutamine gamma-glutamyltransferase E OS=Homo sapiens OX=9606 GN=TGM3 PE=1 SV=4 5.21 1917.8 - 767343 - - - 1.4133 - 2.812 0.664 - 576.4 1 2 0 0.0021 13 0 0 0 1.72E+07 6.95E+05 - - - 6.5982 0.9998 221125_WJC_METTL3_EV_vs_WT_F07.09007.09007.2 1.55E-05 22-Oct K.YKPESEELTAER.L "sp|P07237|PDIA1_HUMAN,tr|A0A7P0TA97|A0A7P0TA97_HUMAN,tr|A0A7P0T8C0|A0A7P0T8C0_HUMAN,tr|H7BZ94|H7BZ94_HUMAN,tr|B3KTQ9|B3KTQ9_HUMAN,tr|A0A7P0TA71|A0A7P0TA71_HUMAN,tr|I3L4M2|I3L4M2_HUMAN,tr|A0A7P0T9D6|A0A7P0T9D6_HUMAN,tr|A0A7P0T9K9|A0A7P0T9K9_HUMAN,tr|H0Y3Z3|H0Y3Z3_HUMAN,tr|A0A7P0TA35|A0A7P0TA35_HUMAN,tr|I3L514|I3L514_HUMAN,tr|A0A7P0TB26|A0A7P0TB26_HUMAN,tr|A0A7P0T9U6|A0A7P0T9U6_HUMAN,tr|I3L0S0|I3L0S0_HUMAN,tr|I3L3P5|I3L3P5_HUMAN,tr|A0A7P0T8J3|A0A7P0T8J3_HUMAN,tr|A0A7P0T8X1|A0A7P0T8X1_HUMAN" 18 1450.694 1.65 97127 9007 2 1450.694554 726.3543 Protein disulfide-isomerase OS=Homo sapiens OX=9606 GN=P4HB PE=1 SV=3 4.49 1918 - 561004 - - - 0.3895 - 1.866 0.474 - 212.2 1 2 0 0.0006 12 0 0 0 1.31E+07 7.93E+06 - - - 4.1831 0.9993 221125_WJC_METTL3_EV_vs_WT_F07.09008.09008.2 0.000113 22-Aug K.YK[136.11]PESEELTAER[166.11].L "sp|P07237|PDIA1_HUMAN,tr|A0A7P0TA97|A0A7P0TA97_HUMAN,tr|A0A7P0T8C0|A0A7P0T8C0_HUMAN,tr|H7BZ94|H7BZ94_HUMAN,tr|B3KTQ9|B3KTQ9_HUMAN,tr|A0A7P0TA71|A0A7P0TA71_HUMAN,tr|I3L4M2|I3L4M2_HUMAN,tr|A0A7P0T9D6|A0A7P0T9D6_HUMAN,tr|A0A7P0T9K9|A0A7P0T9K9_HUMAN,tr|H0Y3Z3|H0Y3Z3_HUMAN,tr|A0A7P0TA35|A0A7P0TA35_HUMAN,tr|I3L514|I3L514_HUMAN,tr|A0A7P0TB26|A0A7P0TB26_HUMAN,tr|A0A7P0T9U6|A0A7P0T9U6_HUMAN,tr|I3L0S0|I3L0S0_HUMAN,tr|I3L3P5|I3L3P5_HUMAN,tr|A0A7P0T8J3|A0A7P0T8J3_HUMAN,tr|A0A7P0T8X1|A0A7P0T8X1_HUMAN" 18 1468.7165 1.65 97128 9008 2 1468.720405 735.3655 Protein disulfide-isomerase OS=Homo sapiens OX=9606 GN=P4HB PE=1 SV=3 4.49 1918.1 - 373103 - - - 2.6867 - 1.669 0.521 - 119.1 1 2 0 0.0039 12 0 0 0 1.31E+07 7.93E+06 - - - 4.2356 0.963 221125_WJC_METTL3_EV_vs_WT_F07.09011.09011.3 0.00198 Sep-36 G.IPHLVTHDAR[166.11].T "sp|P62701|RS4X_HUMAN,sp|P22090|RS4Y1_HUMAN,sp|Q8TD47|RS4Y2_HUMAN,tr|C9JEH7|C9JEH7_HUMAN" 4 1167.6388 0.72 97131 9011 3 1167.640633 390.2202 "40S ribosomal protein S4, X isoform OS=Homo sapiens OX=9606 GN=RPS4X PE=1 SV=2" 6.92 1918.5 - 231852 - - - 1.5604 - 1.956 0.349 - 80.1 1 1 0 0.0018 10 0 0 0 2.24E+06 3.11E+06 - - - 4.3898 0.9994 221125_WJC_METTL3_EV_vs_WT_F07.09014.09014.2 8.39E-05 24-Jul K.QPC[160.03]QPPPVC[160.03]PTPK.C "sp|P22531|SPR2E_HUMAN,sp|P35326|SPR2A_HUMAN,sp|P22532|SPR2D_HUMAN,sp|P35325|SPR2B_HUMAN,sp|Q9BYE4|SPR2G_HUMAN" 5 1504.7167 547.96 97134 9014 2 1504.719681 753.3656 Small proline-rich protein 2E OS=Homo sapiens OX=9606 GN=SPRR2E PE=2 SV=2 8.06 1918.9 - 141842 - - - 2.0103 - 1.458 0.511 - 158.1 1 2 0 0.003 13 0 0 0 2.12E+08 3.86E+05 - - - 3.782 1 221125_WJC_METTL3_EV_vs_WT_F07.09016.09016.3 0.00159 Nov-44 K.YKPESEELTAER.L "sp|P07237|PDIA1_HUMAN,tr|A0A7P0TA97|A0A7P0TA97_HUMAN,tr|A0A7P0T8C0|A0A7P0T8C0_HUMAN,tr|H7BZ94|H7BZ94_HUMAN,tr|B3KTQ9|B3KTQ9_HUMAN,tr|A0A7P0TA71|A0A7P0TA71_HUMAN,tr|I3L4M2|I3L4M2_HUMAN,tr|A0A7P0T9D6|A0A7P0T9D6_HUMAN,tr|A0A7P0T9K9|A0A7P0T9K9_HUMAN,tr|H0Y3Z3|H0Y3Z3_HUMAN,tr|A0A7P0TA35|A0A7P0TA35_HUMAN,tr|I3L514|I3L514_HUMAN,tr|A0A7P0TB26|A0A7P0TB26_HUMAN,tr|A0A7P0T9U6|A0A7P0T9U6_HUMAN,tr|I3L0S0|I3L0S0_HUMAN,tr|I3L3P5|I3L3P5_HUMAN,tr|A0A7P0T8J3|A0A7P0T8J3_HUMAN,tr|A0A7P0T8X1|A0A7P0T8X1_HUMAN" 18 1450.694 1.53 97135 9016 3 1450.694309 484.5719 Protein disulfide-isomerase OS=Homo sapiens OX=9606 GN=P4HB PE=1 SV=3 4.49 1919.1 - 1.19E+07 - - - 0.2206 - 2.315 0.47 - 181.8 1 2 0 0.0003 12 0 0 0 1.22E+08 7.93E+07 - - - 6.1067 1 221125_WJC_METTL3_EV_vs_WT_F07.09017.09017.3 3.69E-06 14/44 R.SQLLGSAHEVQR[166.11].F "sp|Q13813|SPTN1_HUMAN,tr|A0A0D9SF54|A0A0D9SF54_HUMAN,tr|A0A0D9SGF6|A0A0D9SGF6_HUMAN" 3 1333.6978 1.17 97136 9017 3 1333.69812 445.5732 "Spectrin alpha chain, non-erythrocytic 1 OS=Homo sapiens OX=9606 GN=SPTAN1 PE=1 SV=3" 6.47 1919.2 - 1.30E+06 - - - 0.2534 - 2.396 0.504 - 315 1 2 0 0.0003 12 0 0 0 3.02E+07 2.57E+07 - - - 6.5811 0.9992 221125_WJC_METTL3_EV_vs_WT_F07.09018.09018.3 0.000479 Sep-36 R.GYDDR[166.11]DYYSR[166.11].S "sp|P62995|TRA2B_HUMAN,tr|H7BXF3|H7BXF3_HUMAN,tr|H7C2L4|H7C2L4_HUMAN" 3 1328.5536 1.56 97137 9018 3 1328.554459 443.8585 Transformer-2 protein homolog beta OS=Homo sapiens OX=9606 GN=TRA2B PE=1 SV=1 4.43 1919.2 - 3.17E+06 - - - 0.621 - 1.418 0.457 - 117.2 1 2 1 0.0008 10 0 0 0 6.96E+07 4.47E+07 - - - 4.6548 0.9998 221125_WJC_METTL3_EV_vs_WT_F07.09019.09019.2 4.50E-05 20-Dec K.GIPHLVTHDAR[166.11].T "sp|P62701|RS4X_HUMAN,sp|P22090|RS4Y1_HUMAN,sp|Q8TD47|RS4Y2_HUMAN,tr|C9JEH7|C9JEH7_HUMAN" 4 1224.6603 1.01 97138 9019 2 1224.659713 613.3374 "40S ribosomal protein S4, X isoform OS=Homo sapiens OX=9606 GN=RPS4X PE=1 SV=2" 6.92 1919.3 - 2.00E+06 - - - -0.4581 - 2.024 0.473 - 476.4 1 2 0 -0.0006 11 0 0 0 3.42E+07 3.40E+07 - - - 4.4418 0.9822 221125_WJC_METTL3_EV_vs_WT_F07.09020.09020.2 0.00171 14-Dec P.HLVTHDAR[166.11].T "sp|P62701|RS4X_HUMAN,sp|P22090|RS4Y1_HUMAN,sp|Q8TD47|RS4Y2_HUMAN,tr|C9JEH7|C9JEH7_HUMAN" 4 957.502 0.84 97139 9020 2 957.50308 479.7583 "40S ribosomal protein S4, X isoform OS=Homo sapiens OX=9606 GN=RPS4X PE=1 SV=2" 6.92 1919.3 - 1.68E+06 - - - 1.1457 - 2.113 0.366 - 627.6 1 1 0 0.0011 8 0 0 0 1.91E+07 2.27E+07 - - - 4.0002 0.9985 221125_WJC_METTL3_EV_vs_WT_F07.09023.09023.3 0.00689 Dec-44 R.LR[166.11]LEEDK[136.11]PAVER[166.11].C sp|Q9Y5J1|UTP18_HUMAN 1 1481.8196 0.98 97142 9023 3 1481.819836 494.9472 U3 small nucleolar RNA-associated protein 18 homolog OS=Homo sapiens OX=9606 GN=UTP18 PE=1 SV=3 4.87 1919.6 - 813040 - - - 0.1377 - 1.984 0.334 - 243.9 1 2 1 0.0002 12 0 0 0 3.71E+06 3.77E+06 - - - 4.1627 0.9998 221125_WJC_METTL3_EV_vs_WT_F07.09027.09027.2 4.45E-06 24-Nov R.AENQSTTLPGPGR.N sp|Q7Z353|HDX_HUMAN 1 1326.6528 3.13 97146 9027 2 1326.65331 664.3337 Highly divergent homeobox OS=Homo sapiens OX=9606 GN=HDX PE=1 SV=1 6.05 1920.1 - 464361 - - - 0.3905 - 2.095 0.476 - 290.9 1 2 0 0.0005 13 0 0 0 2.40E+07 7.67E+06 - - - 4.4547 0.9955 221125_WJC_METTL3_EV_vs_WT_F07.09028.09028.2 0.0241 18-Jun R.GPLPLSSQHR.G "sp|P43243|MATR3_HUMAN,tr|A8MXP9|A8MXP9_HUMAN,tr|D6R991|D6R991_HUMAN,tr|A0A0R4J2E8|A0A0R4J2E8_HUMAN,tr|D6R8Z5|D6R8Z5_HUMAN,tr|D6REM6|D6REM6_HUMAN" 6 1090.5883 1.36 97147 9028 2 1090.590702 546.3014 Matrin-3 OS=Homo sapiens OX=9606 GN=MATR3 PE=1 SV=2 9.76 1920.2 - 408368 - - - 2.164 - 1.266 0.299 - 128.9 1 2 0 0.0024 10 0 0 0 1.86E+07 1.37E+07 - - - 1.907 1 221125_WJC_METTL3_EV_vs_WT_F07.09029.09029.2 2.67E-11 15/24 R.TPC[160.03]NAGTFSQPEK.V "sp|O43684|BUB3_HUMAN,tr|J3QT28|J3QT28_HUMAN,tr|J3QSX4|J3QSX4_HUMAN" 3 1435.6402 0.6 97148 9029 2 1435.640142 718.8274 Mitotic checkpoint protein BUB3 OS=Homo sapiens OX=9606 GN=BUB3 PE=1 SV=1 5.66 1920.3 - 346304 - - - -0.0258 - 3.006 0.722 - 771.7 1 2 0 0 13 0 0 0 1.05E+07 1.75E+07 - - - 7.1984 0.9999 221125_WJC_METTL3_EV_vs_WT_F07.09031.09031.2 2.06E-06 26-Nov K.NIVQHTTDSSLEEK[136.11].Q sp|Q9H501|ESF1_HUMAN 1 1607.7882 0.83 97150 9031 2 1607.786932 804.9014 ESF1 homolog OS=Homo sapiens OX=9606 GN=ESF1 PE=1 SV=1 4.65 1920.6 - 310408 - - - -0.8073 - 2.628 0.478 - 264 1 2 0 -0.0013 14 0 0 0 2.37E+06 2.85E+06 - - - 4.9958 1 221125_WJC_METTL3_EV_vs_WT_F07.09032.09032.2 5.50E-08 26-Oct K.NIVQHTTDSSLEEK.Q sp|Q9H501|ESF1_HUMAN 1 1599.774 0.83 97151 9032 2 1599.773947 800.8943 ESF1 homolog OS=Homo sapiens OX=9606 GN=ESF1 PE=1 SV=1 4.65 1920.7 - 268087 - - - -0.0519 - 2.553 0.602 - 271 1 2 0 -0.0001 14 0 0 0 2.37E+06 2.85E+06 - - - 5.8394 0.9999 221125_WJC_METTL3_EV_vs_WT_F07.09038.09038.2 0.000454 24-Dec K.GPGEVAGTVTGQK[136.11].R "sp|Q86U44|MTA70_HUMAN,tr|F5H6D8|F5H6D8_HUMAN,tr|H0YFV6|H0YFV6_HUMAN,tr|B4DTN4|B4DTN4_HUMAN" 4 1207.6288 0.02 97156 9038 2 1207.629543 604.8217 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 6 1921.4 - 2.53E+06 - - - 0.602 - 2.49 0.483 - 588.7 1 2 0 0.0007 13 0 0 0 7.88E+06 4.50E+08 - - - 4.9496 0.9803 221125_WJC_METTL3_EV_vs_WT_F07.09039.09039.2 1.49E-05 16-Dec L.PHLVTHDAR[166.11].T "sp|P62701|RS4X_HUMAN,sp|P22090|RS4Y1_HUMAN,sp|Q8TD47|RS4Y2_HUMAN,tr|C9JEH7|C9JEH7_HUMAN" 4 1054.5547 1.36 97157 9039 2 1054.55505 528.2846 "40S ribosomal protein S4, X isoform OS=Homo sapiens OX=9606 GN=RPS4X PE=1 SV=2" 7.33 1921.5 - 1.68E+06 - - - 0.2873 - 2.398 0.26 - 626.4 1 1 0 0.0003 9 0 0 0 1.86E+07 1.37E+07 - - - 3.4916 0.994 221125_WJC_METTL3_EV_vs_WT_F07.09044.09044.2 0.00253 18-Sep R.GYDDRDYYSR.S "sp|P62995|TRA2B_HUMAN,tr|H7BXF3|H7BXF3_HUMAN,tr|H7C2L4|H7C2L4_HUMAN" 3 1308.5371 1.64 97162 9044 2 1308.537595 655.2758 Transformer-2 protein homolog beta OS=Homo sapiens OX=9606 GN=TRA2B PE=1 SV=1 4.43 1922 - 728694 - - - 0.3829 - 1.364 0.419 - 160.6 1 2 1 0.0005 10 0 0 0 7.31E+06 4.46E+06 - - - 3.0021 0.9938 221125_WJC_METTL3_EV_vs_WT_F07.09046.09046.2 0.0673 13/16 R.ENLRQEIEK.F sp|P15924|DESP_HUMAN 1 1157.6041 74.3 97164 9046 2 1157.603912 579.8093 Desmoplakin OS=Homo sapiens OX=9606 GN=DSP PE=1 SV=3 4.79 1922.3 - 498892 - - - -0.1201 - 2.314 0.195 - 713.7 1 2 1 -0.0001 9 0 0 0 8.57E+06 1.15E+05 - - - 2.9084 0.9997 221125_WJC_METTL3_EV_vs_WT_F07.09048.09048.2 0.00974 18-Nov K.RFPGYDSESK.E "sp|P46777|RL5_HUMAN,tr|A0A2R8Y6J3|A0A2R8Y6J3_HUMAN" 2 1184.5462 0.93 97166 9048 2 1184.547176 593.2804 60S ribosomal protein L5 OS=Homo sapiens OX=9606 GN=RPL5 PE=1 SV=3 6.07 1922.5 - 324103 - - - 0.8223 - 1.814 0.421 - 414.3 1 2 0 0.001 10 0 0 0 2.43E+07 2.63E+07 - - - 3.8125 1 221125_WJC_METTL3_EV_vs_WT_F07.09052.09052.3 4.20E-09 17/36 R.TKYEHELALR.Q sp|P08779|K1C16_HUMAN 1 1258.667 30174.48 97168 9052 3 1258.667777 420.5629 "Keratin, type I cytoskeletal 16 OS=Homo sapiens OX=9606 GN=KRT16 PE=1 SV=4" 6.42 1923.1 - 1.92E+06 - - - 0.6284 - 2.928 0.59 - 431.1 1 2 1 0.0008 10 0 0 0 3.44E+09 1.14E+05 - - - 8.2552 0.9899 221125_WJC_METTL3_EV_vs_WT_F07.09054.09054.3 0.000622 Aug-40 F.VTFDDHDSVDK[136.11].L "sp|Q32P51|RA1L2_HUMAN,sp|P09651|ROA1_HUMAN,tr|A0A7I2YQX9|A0A7I2YQX9_HUMAN,tr|F8VZ49|F8VZ49_HUMAN,tr|A0A7I2V3R8|A0A7I2V3R8_HUMAN,tr|F8VTQ5|F8VTQ5_HUMAN,tr|F8W6I7|F8W6I7_HUMAN,tr|H0YH80|H0YH80_HUMAN,tr|A0A7I2V2L6|A0A7I2V2L6_HUMAN,tr|A0A7I2V3W0|A0A7I2V3W0_HUMAN,tr|A0A7I2V5U9|A0A7I2V5U9_HUMAN,tr|A0A2R8Y4L2|A0A2R8Y4L2_HUMAN" 12 1284.5714 2.94 97170 9054 3 1284.573554 429.1977 Heterogeneous nuclear ribonucleoprotein A1-like 2 OS=Homo sapiens OX=9606 GN=HNRNPA1L2 PE=2 SV=2 4.13 1923.2 - 774394 - - - 1.7072 - 1.89 0.481 - 85.1 1 1 0 0.0022 11 0 0 0 1.50E+07 5.09E+06 - - - 5.7105 0.9951 221125_WJC_METTL3_EV_vs_WT_F07.09058.09058.2 0.00236 16-Oct K.KQEYLEVQR.Q "sp|O14964|HGS_HUMAN,tr|A0A7I2V2K2|A0A7I2V2K2_HUMAN,tr|A0A7I2V637|A0A7I2V637_HUMAN,tr|A0A7I2V6E0|A0A7I2V6E0_HUMAN,tr|A0A7I2V307|A0A7I2V307_HUMAN,tr|A0A7I2V3Z1|A0A7I2V3Z1_HUMAN,tr|A0A7I2V5A3|A0A7I2V5A3_HUMAN,tr|A0A7I2V2R9|A0A7I2V2R9_HUMAN,tr|A0A7I2V3I8|A0A7I2V3I8_HUMAN,tr|A0A7I2V2D8|A0A7I2V2D8_HUMAN,tr|A0A7I2V2W5|A0A7I2V2W5_HUMAN,tr|I3L1E3|I3L1E3_HUMAN,tr|A0A7I2V5A2|A0A7I2V5A2_HUMAN,tr|A0A7I2V3J3|A0A7I2V3J3_HUMAN,tr|A0A7I2V3F9|A0A7I2V3F9_HUMAN" 15 1191.6248 999 97174 9058 2 1191.627741 596.8197 Hepatocyte growth factor-regulated tyrosine kinase substrate OS=Homo sapiens OX=9606 GN=HGS PE=1 SV=1 6.14 1923.8 - 376464 - - - 2.479 - 1.858 0.158 - 353.3 1 2 0 0.003 9 0 0 0 2.33E+06 0.00E+00 - - - 1.9993 1 221125_WJC_METTL3_EV_vs_WT_F07.09060.09060.3 2.76E-09 14/52 K.C[160.03]GFC[160.03]HVGEEENEAR.G "sp|Q8IWS0|PHF6_HUMAN,tr|Q5JRC6|Q5JRC6_HUMAN,tr|A0A0D9SGE8|A0A0D9SGE8_HUMAN" 3 1692.6621 0.81 97176 9060 3 1692.659108 565.228 PHD finger protein 6 OS=Homo sapiens OX=9606 GN=PHF6 PE=1 SV=1 4.48 1924 - 266184 - - - -1.7405 - 2.91 0.687 - 260.6 1 2 0 -0.0029 14 0 0 0 2.56E+07 3.16E+07 - - - 9.0372 0.9927 221125_WJC_METTL3_EV_vs_WT_F07.09062.09062.2 0.0863 20-Aug K.HIEVQVAQETR[166.11].N "sp|O60271|JIP4_HUMAN,tr|A0A087X2D8|A0A087X2D8_HUMAN" 2 1318.6869 0.97 97178 9062 2 1318.690441 660.3507 C-Jun-amino-terminal kinase-interacting protein 4 OS=Homo sapiens OX=9606 GN=SPAG9 PE=1 SV=4 5.4 1924.3 - 172399 - - - 2.6981 - 1.5 0.226 - 210.4 1 2 0 0.0036 11 0 0 0 1.00E+06 1.03E+06 - - - 1.806 0.9998 221125_WJC_METTL3_EV_vs_WT_F07.09063.09063.2 0.00182 18-Aug K.TTESHMDWEK.V "sp|P17480|UBF1_HUMAN,tr|E9PMM2|E9PMM2_HUMAN,tr|E9PKP7|E9PKP7_HUMAN" 3 1262.5238 1 97179 9063 2 1262.522998 632.2692 Nucleolar transcription factor 1 OS=Homo sapiens OX=9606 GN=UBTF PE=1 SV=1 4.65 1924.4 - 148982 - - - -0.5972 - 1.752 0.498 - 170.3 1 2 0 -0.0008 10 0 0 0 1.15E+06 1.14E+06 - - - 4.2842 0.9999 221125_WJC_METTL3_EV_vs_WT_F07.09064.09064.2 2.34E-07 28-Nov K.AQGATGEVYC[160.03]PSGEK.C sp|Q9H1B7|I2BPL_HUMAN 1 1552.6828 1.82 97180 9064 2 1552.683558 777.3487 Probable E3 ubiquitin-protein ligase IRF2BPL OS=Homo sapiens OX=9606 GN=IRF2BPL PE=1 SV=1 4.53 1924.5 - 138474 - - - 0.5062 - 2.398 0.573 - 412.5 1 2 0 0.0008 15 0 0 0 3.63E+06 1.99E+06 - - - 5.4233 1 221125_WJC_METTL3_EV_vs_WT_F07.09069.09069.3 5.65E-09 15/56 R.VFLKPAEENSGNASR.C sp|Q5T3J3|LRIF1_HUMAN 1 1617.8111 1.83 97183 9069 3 1617.812301 540.2776 Ligand-dependent nuclear receptor-interacting factor 1 OS=Homo sapiens OX=9606 GN=LRIF1 PE=1 SV=1 6.11 1925.1 - 1.32E+06 - - - 0.7523 - 2.705 0.612 - 255.9 1 2 0 0.0012 15 0 0 0 5.46E+07 2.98E+07 - - - 7.9594 0.9976 221125_WJC_METTL3_EV_vs_WT_F07.09072.09072.2 1.68E-05 18-Oct R.TKYEHELALR.Q sp|P08779|K1C16_HUMAN 1 1258.667 999 97186 9072 2 1258.66883 630.3408 "Keratin, type I cytoskeletal 16 OS=Homo sapiens OX=9606 GN=KRT16 PE=1 SV=4" 6.42 1925.4 - 374284 - - - 1.465 - 2.033 0.508 - 352.6 1 2 1 0.0018 10 0 0 0 1.66E+08 0.00E+00 - - - 4.773 0.9997 221125_WJC_METTL3_EV_vs_WT_F07.09075.09075.2 0.292 18-Oct K.R[166.11]FPGYDSESK[136.11].E "sp|P46777|RL5_HUMAN,tr|A0A2R8Y6J3|A0A2R8Y6J3_HUMAN" 2 1202.5687 0.56 97189 9075 2 1202.569324 602.2916 60S ribosomal protein L5 OS=Homo sapiens OX=9606 GN=RPL5 PE=1 SV=3 6.07 1925.8 - 285261 - - - 0.5422 - 2.173 0.318 - 317.9 1 2 0 0.0007 10 0 0 0 1.52E+06 2.71E+06 - - - 3.5559 1 221125_WJC_METTL3_EV_vs_WT_F07.09076.09076.2 8.70E-07 15/28 K.VDNSSLTGESEPQTR.S "sp|P05023|AT1A1_HUMAN,sp|P13637|AT1A3_HUMAN,sp|P50993|AT1A2_HUMAN,sp|P20648|ATP4A_HUMAN,tr|A0A0A0MT26|A0A0A0MT26_HUMAN,tr|M0QXF2|M0QXF2_HUMAN,tr|A0A2R8YEY8|A0A2R8YEY8_HUMAN,tr|B1AKY9|B1AKY9_HUMAN,tr|M0R116|M0R116_HUMAN" 9 1618.7435 1.31 97190 9076 2 1618.745704 810.379 Sodium\potassium-transporting ATPase subunit alpha-1 OS=Homo sapiens OX=9606 GN=ATP1A1 PE=1 SV=1 4.14 1925.9 - 252486 - - - 1.3875 - 2.511 0.614 - 408 1 2 0 0.0022 15 0 0 0 6.82E+07 5.20E+07 - - - 5.8388 1 221125_WJC_METTL3_EV_vs_WT_F07.09077.09077.2 2.09E-08 28-Dec K.VDNSSLTGESEPQTR[166.11].S "sp|P05023|AT1A1_HUMAN,sp|P13637|AT1A3_HUMAN,sp|P50993|AT1A2_HUMAN,sp|P20648|ATP4A_HUMAN,tr|A0A0A0MT26|A0A0A0MT26_HUMAN,tr|M0QXF2|M0QXF2_HUMAN,tr|A0A2R8YEY8|A0A2R8YEY8_HUMAN,tr|B1AKY9|B1AKY9_HUMAN,tr|M0R116|M0R116_HUMAN" 9 1628.7517 1.31 97191 9077 2 1628.757076 815.3831 Sodium\potassium-transporting ATPase subunit alpha-1 OS=Homo sapiens OX=9606 GN=ATP1A1 PE=1 SV=1 4.14 1926 - 237655 - - - 3.2835 - 2.615 0.625 - 503.3 1 2 0 0.0053 15 0 0 0 6.82E+07 5.20E+07 - - - 6.0189 0.9979 221125_WJC_METTL3_EV_vs_WT_F07.09079.09079.2 0.00838 24-Aug R.AENQSTTLPGPGR[166.11].N sp|Q7Z353|HDX_HUMAN 1 1336.6611 2.92 97193 9079 2 1336.663155 669.3378 Highly divergent homeobox OS=Homo sapiens OX=9606 GN=HDX PE=1 SV=1 6.05 1926.3 - 492409 - - - 1.5658 - 1.397 0.313 - 106.3 1 2 0 0.0021 13 0 0 0 2.24E+07 7.67E+06 - - - 2.2102 1 221125_WJC_METTL3_EV_vs_WT_F07.09081.09081.3 0.000111 14/40 K.GIPHLVTHDAR[166.11].T "sp|P62701|RS4X_HUMAN,sp|P22090|RS4Y1_HUMAN,sp|Q8TD47|RS4Y2_HUMAN,tr|C9JEH7|C9JEH7_HUMAN" 4 1224.6603 1.06 97194 9081 3 1224.660915 409.2274 "40S ribosomal protein S4, X isoform OS=Homo sapiens OX=9606 GN=RPS4X PE=1 SV=2" 6.92 1926.6 - 1.84E+07 - - - 0.5234 - 2.558 0.513 - 324.5 1 2 0 0.0006 11 0 0 0 2.91E+08 2.74E+08 - - - 6.9274 1 221125_WJC_METTL3_EV_vs_WT_F07.09085.09085.3 2.93E-09 20/52 K.C[160.03]GFC[160.03]HVGEEENEAR[166.11].G "sp|Q8IWS0|PHF6_HUMAN,tr|Q5JRC6|Q5JRC6_HUMAN,tr|A0A0D9SGE8|A0A0D9SGE8_HUMAN" 3 1702.6703 0.81 97197 9085 3 1702.671619 568.5641 PHD finger protein 6 OS=Homo sapiens OX=9606 GN=PHF6 PE=1 SV=1 4.48 1926.9 - 2.69E+06 - - - 0.7606 - 3.618 0.737 - 769.7 1 2 0 0.0013 14 0 0 0 2.56E+07 3.15E+07 - - - 10.1738 0.9999 221125_WJC_METTL3_EV_vs_WT_F07.09086.09086.3 0.0017 16/44 K.QIDQLSKDEVGK.L "sp|Q15643|TRIPB_HUMAN,tr|H0YJ97|H0YJ97_HUMAN" 2 1358.7042 1.3 97198 9086 3 1358.704673 453.9087 Thyroid receptor-interacting protein 11 OS=Homo sapiens OX=9606 GN=TRIP11 PE=1 SV=3 4.56 1927 - 1.44E+06 - - - 0.3783 - 2.947 0.463 - 463.9 1 2 1 0.0005 12 0 0 0 2.10E+08 1.62E+08 - - - 6.6976 0.9995 221125_WJC_METTL3_EV_vs_WT_F07.09089.09089.3 0.000741 Dec-40 R.DLYDDKDGLRK.E sp|Q12874|SF3A3_HUMAN 1 1336.6623 4.32 97201 9089 3 1336.663046 446.5614 Splicing factor 3A subunit 3 OS=Homo sapiens OX=9606 GN=SF3A3 PE=1 SV=1 4.58 1927.3 - 981119 - - - 0.5626 - 2.363 0.365 - 151.9 1 2 1 0.0008 11 0 0 0 1.08E+08 2.50E+07 - - - 5.0521 0.9997 221125_WJC_METTL3_EV_vs_WT_F07.09090.09090.2 1.95E-05 14-Oct K.YEHELALR.Q sp|P08779|K1C16_HUMAN 1 1029.5243 159.48 97202 9090 2 1029.525033 515.7694 "Keratin, type I cytoskeletal 16 OS=Homo sapiens OX=9606 GN=KRT16 PE=1 SV=4" 5.4 1927.4 - 908224 - - - 0.6692 - 1.646 0.431 - 486.2 1 2 0 0.0007 8 0 0 0 7.89E+07 4.95E+05 - - - 3.7271 0.8631 221125_WJC_METTL3_EV_vs_WT_F07.09095.09095.3 0.0688 Nov-40 R.DHPLPEVAHVK.H "sp|P13073|COX41_HUMAN,tr|Q86WV2|Q86WV2_HUMAN,tr|H3BN72|H3BN72_HUMAN,tr|H3BPG0|H3BPG0_HUMAN,tr|H3BNV9|H3BNV9_HUMAN" 5 1240.6564 1.72 97207 9095 3 1240.656582 414.5594 "Cytochrome c oxidase subunit 4 isoform 1, mitochondrial OS=Homo sapiens OX=9606 GN=COX4I1 PE=1 SV=1" 5.99 1928.1 - 447820 - - - 0.1298 - 1.807 0.003 - 122.2 1 2 0 0.0002 11 0 0 0 2.74E+08 1.59E+08 - - - 0.2542 0.9503 221125_WJC_METTL3_EV_vs_WT_F07.09097.09097.2 0.166 24-Jul K.DTDGGPKEEESPV.- sp|P53985|MOT1_HUMAN 1 1358.5838 1.04 97209 9097 2 1358.585745 680.2992 Monocarboxylate transporter 1 OS=Homo sapiens OX=9606 GN=SLC16A1 PE=1 SV=3 3.83 1928.3 - 336733 - - - 1.4545 - 1.151 0.289 - 87 1 2 1 0.002 13 0 0 0 5.12E+06 4.91E+06 - - - 1.5359 1 221125_WJC_METTL3_EV_vs_WT_F07.09099.09099.2 2.40E-08 28-Oct K.AQGATGEVYC[160.03]PSGEK[136.11].C sp|Q9H1B7|I2BPL_HUMAN 1 1560.697 1.82 97211 9099 2 1560.698896 781.3558 Probable E3 ubiquitin-protein ligase IRF2BPL OS=Homo sapiens OX=9606 GN=IRF2BPL PE=1 SV=1 4.53 1928.6 - 241691 - - - 1.2328 - 2.307 0.63 - 277.9 1 2 0 0.0019 15 0 0 0 3.63E+06 1.99E+06 - - - 5.7488 0.9763 221125_WJC_METTL3_EV_vs_WT_F07.09100.09100.2 0.00966 30-Jun R.SGGGGGGGLGSGGSIR.S sp|P35527|K1C9_HUMAN 1 1231.5905 999 97212 9100 2 1231.591774 616.8025 "Keratin, type I cytoskeletal 9 OS=Homo sapiens OX=9606 GN=KRT9 PE=1 SV=3" 9.47 1928.7 - 81154.3 - - - 1.0133 - 1.312 0.107 - 63.3 4 2 0 0.0012 16 0 0 0 7.60E+05 0.00E+00 - - - 0.2296 0.9995 221125_WJC_METTL3_EV_vs_WT_F07.09104.09104.3 2.92E-05 14/40 K.GTEVQVDDIK[136.11]R[166.11].V sp|Q9Y230|RUVB2_HUMAN 1 1276.6742 15.02 97214 9104 3 1276.670838 426.5653 RuvB-like 2 OS=Homo sapiens OX=9606 GN=RUVBL2 PE=1 SV=3 4.56 1929.2 - 2.54E+06 - - - -2.6334 - 2.471 0.314 - 525.1 1 2 0 -0.0034 11 0 0 0 5.69E+08 3.79E+07 - - - 4.6097 1 221125_WJC_METTL3_EV_vs_WT_F07.09106.09106.3 1.83E-06 13/36 R.R[166.11]GEDMMHPLK[136.11].V "sp|O60884|DNJA2_HUMAN,tr|A0A087WT48|A0A087WT48_HUMAN" 2 1230.5968 1.21 97216 9106 3 1230.596831 411.2062 DnaJ homolog subfamily A member 2 OS=Homo sapiens OX=9606 GN=DNAJA2 PE=1 SV=1 6.75 1929.3 - 1.82E+06 - - - 0.0106 - 2.127 0.532 - 238.1 1 2 0 0 10 0 0 0 1.80E+07 1.49E+07 - - - 6.6754 0.999 221125_WJC_METTL3_EV_vs_WT_F07.09108.09108.2 0.00653 13/22 K.QIDQLSK[136.11]DEVGK[136.11].L "sp|Q15643|TRIPB_HUMAN,tr|H0YJ97|H0YJ97_HUMAN" 2 1374.7326 1.2 97218 9108 2 1374.731951 688.3736 Thyroid receptor-interacting protein 11 OS=Homo sapiens OX=9606 GN=TRIP11 PE=1 SV=3 4.56 1929.5 - 766844 - - - -0.4423 - 2.747 0.529 - 694.1 1 2 1 -0.0006 12 0 0 0 2.75E+07 2.29E+07 - - - 5.6068 1 221125_WJC_METTL3_EV_vs_WT_F07.09110.09110.2 1.69E-06 16/22 K.QIDQLSKDEVGK.L "sp|Q15643|TRIPB_HUMAN,tr|H0YJ97|H0YJ97_HUMAN" 2 1358.7042 1.02 97220 9110 2 1358.703353 680.3594 Thyroid receptor-interacting protein 11 OS=Homo sapiens OX=9606 GN=TRIP11 PE=1 SV=3 4.56 1929.8 - 717720 - - - -0.5932 - 2.686 0.562 - 839.4 1 2 1 -0.0008 12 0 0 0 2.27E+07 2.23E+07 - - - 5.7914 0.9644 221125_WJC_METTL3_EV_vs_WT_F07.09112.09112.2 0.00719 12-Jul W.SSIQAHK[136.11].K "sp|Q86U44|MTA70_HUMAN,tr|B4E349|B4E349_HUMAN,tr|F5H6D8|F5H6D8_HUMAN,tr|B4DTN4|B4DTN4_HUMAN" 4 777.4225 0.001 97222 9112 2 777.422178 389.7185 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 8.49 1930 - 356498 - - - -0.3524 - 1.371 0.377 - 166.6 1 1 0 -0.0003 7 0 0 0 0.00E+00 3.80E+06 - - - 2.8252 0.9999 221125_WJC_METTL3_EV_vs_WT_F07.09115.09115.2 3.60E-06 20-Nov K.GTEVQVDDIK[136.11]R[166.11].V sp|Q9Y230|RUVB2_HUMAN 1 1276.6742 0.001 97225 9115 2 1276.673474 639.3444 RuvB-like 2 OS=Homo sapiens OX=9606 GN=RUVBL2 PE=1 SV=3 4.56 1930.4 - 138821 - - - -0.5687 - 2.355 0.454 - 627 1 2 0 -0.0007 11 0 0 0 0.00E+00 2.83E+06 - - - 4.7112 0.9998 221125_WJC_METTL3_EV_vs_WT_F07.09118.09118.2 0.00178 20-Oct K.EQELNQSISEK.E "sp|Q15643|TRIPB_HUMAN,tr|H0YJ97|H0YJ97_HUMAN" 2 1303.6256 1.32 97226 9118 2 1303.625127 652.8201 Thyroid receptor-interacting protein 11 OS=Homo sapiens OX=9606 GN=TRIP11 PE=1 SV=3 4.25 1930.9 - 544778 - - - -0.3437 - 2.039 0.388 - 375.2 1 2 0 -0.0004 11 0 0 0 4.91E+07 3.72E+07 - - - 3.834 0.9949 221125_WJC_METTL3_EV_vs_WT_F07.09122.09122.3 0.00583 Nov-40 R.ASRDEIFAQSK.E sp|P35580|MYH10_HUMAN 1 1250.6255 0.91 97230 9122 3 1250.626792 417.8824 Myosin-10 OS=Homo sapiens OX=9606 GN=MYH10 PE=1 SV=3 6.11 1931.2 - 1.41E+06 - - - 1.0211 - 1.71 0.292 - 157.1 1 2 1 0.0013 11 0 0 0 6.83E+07 7.49E+07 - - - 3.3192 0.9992 221125_WJC_METTL3_EV_vs_WT_F07.09124.09124.2 1.45 20-Oct K.EQELNQSISEK[136.11].E "sp|Q15643|TRIPB_HUMAN,tr|H0YJ97|H0YJ97_HUMAN" 2 1311.6398 1.32 97232 9124 2 1311.6392 656.8272 Thyroid receptor-interacting protein 11 OS=Homo sapiens OX=9606 GN=TRIP11 PE=1 SV=3 4.25 1931.5 - 399255 - - - -0.4384 - 1.919 0.243 - 370.5 1 2 0 -0.0006 11 0 0 0 4.91E+07 3.72E+07 - - - 2.5989 0.9956 221125_WJC_METTL3_EV_vs_WT_F07.09130.09130.2 0.000457 20-Nov R.ASRDEIFAQSK.E sp|P35580|MYH10_HUMAN 1 1250.6255 0.89 97236 9130 2 1250.624593 626.32 Myosin-10 OS=Homo sapiens OX=9606 GN=MYH10 PE=1 SV=3 6.11 1932.3 - 284431 - - - -0.7372 - 1.995 0.331 - 405.7 1 2 1 -0.0009 11 0 0 0 1.33E+07 1.49E+07 - - - 3.3538 0.999 221125_WJC_METTL3_EV_vs_WT_F07.09140.09140.3 2.63E-08 19/60 R.TPVEASHPVENASVPR.P sp|Q8TBA6|GOGA5_HUMAN 1 1688.8482 1.87 97244 9140 3 1688.847208 563.9567 Golgin subfamily A member 5 OS=Homo sapiens OX=9606 GN=GOLGA5 PE=1 SV=3 5.37 1933.4 - 2.32E+06 - - - -0.5862 - 3.503 0.592 - 475.2 1 1 0 -0.001 16 0 0 0 3.69E+07 1.97E+07 - - - 8.3566 0.9994 221125_WJC_METTL3_EV_vs_WT_F07.09144.09144.3 3.84E-05 Dec-48 K.TVIKPESC[160.03]VPC[160.03]GK.R "sp|Q9H0H5|RGAP1_HUMAN,tr|F8VRL2|F8VRL2_HUMAN" 2 1473.732 1.57 97248 9144 3 1473.728587 492.2513 Rac GTPase-activating protein 1 OS=Homo sapiens OX=9606 GN=RACGAP1 PE=1 SV=1 7.72 1933.9 - 415623 - - - -2.2962 - 2.044 0.34 - 154.7 1 2 0 -0.0034 13 0 0 0 1.64E+07 1.04E+07 - - - 4.2681 1 221125_WJC_METTL3_EV_vs_WT_F07.09150.09150.3 1.36E-06 13/40 K.GIPHLVTHDAR.T "sp|P62701|RS4X_HUMAN,sp|P22090|RS4Y1_HUMAN,sp|Q8TD47|RS4Y2_HUMAN,tr|C9JEH7|C9JEH7_HUMAN" 4 1214.652 1.05 97252 9150 3 1214.650299 405.8913 "40S ribosomal protein S4, X isoform OS=Homo sapiens OX=9606 GN=RPS4X PE=1 SV=2" 6.92 1934.6 - 3.18E+06 - - - -1.4037 - 2.411 0.538 - 303.1 1 2 0 -0.0017 11 0 0 0 2.93E+08 2.78E+08 - - - 7.0377 0.9985 221125_WJC_METTL3_EV_vs_WT_F07.09151.09151.3 1.11E-05 17/60 R.TPVEASHPVENASVPR[166.11].P sp|Q8TBA6|GOGA5_HUMAN 1 1698.8565 1.87 97253 9151 3 1698.854508 567.2928 Golgin subfamily A member 5 OS=Homo sapiens OX=9606 GN=GOLGA5 PE=1 SV=3 5.37 1934.7 - 1.57E+06 - - - -1.1537 - 3.317 0.546 - 337.3 1 1 0 -0.002 16 0 0 0 3.69E+07 1.97E+07 - - - 7.7034 0.9952 221125_WJC_METTL3_EV_vs_WT_F07.09152.09152.2 0.0636 20-Dec R.ASR[166.11]DEIFAQSK[136.11].E sp|P35580|MYH10_HUMAN 1 1268.648 0.89 97254 9152 2 1268.648179 635.3313 Myosin-10 OS=Homo sapiens OX=9606 GN=MYH10 PE=1 SV=3 6.11 1934.8 - 1.10E+06 - - - 0.1529 - 2.082 0.292 - 615.3 1 2 1 0.0002 11 0 0 0 1.33E+07 1.49E+07 - - - 3.1815 0.7868 221125_WJC_METTL3_EV_vs_WT_F07.09155.09155.3 0.175 Aug-56 K.VDNSSLTGESEPQTR[166.11].S "sp|P05023|AT1A1_HUMAN,sp|P13637|AT1A3_HUMAN,sp|P50993|AT1A2_HUMAN,sp|P20648|ATP4A_HUMAN,tr|A0A0A0MT26|A0A0A0MT26_HUMAN,tr|M0QXF2|M0QXF2_HUMAN,tr|A0A2R8YEY8|A0A2R8YEY8_HUMAN,tr|B1AKY9|B1AKY9_HUMAN,tr|M0R116|M0R116_HUMAN" 9 1628.7517 1.67 97257 9155 3 1628.743702 543.9245 Sodium\potassium-transporting ATPase subunit alpha-1 OS=Homo sapiens OX=9606 GN=ATP1A1 PE=1 SV=1 4.14 1935.2 - 276171 - - - -4.9277 - 1.422 0.181 - 50.6 1 2 0 -0.008 15 0 0 0 8.96E+06 5.38E+06 - - - 1.4744 0.9997 221125_WJC_METTL3_EV_vs_WT_F07.09157.09157.2 0.00244 16-Aug K.ESEFDDEPK[136.11].F "sp|Q9Y2W1|TR150_HUMAN,tr|A0A3B3ITZ9|A0A3B3ITZ9_HUMAN" 2 1102.4546 3.71 97259 9157 2 1102.455098 552.2346 Thyroid hormone receptor-associated protein 3 OS=Homo sapiens OX=9606 GN=THRAP3 PE=1 SV=2 3.83 1935.4 - 182934 - - - 0.4517 - 1.515 0.487 - 259.6 1 2 0 0.0005 9 0 0 0 2.19E+07 5.89E+06 - - - 3.8396 0.9947 221125_WJC_METTL3_EV_vs_WT_F07.09160.09160.3 0.000438 Dec-40 R.ASR[166.11]DEIFAQSK[136.11].E sp|P35580|MYH10_HUMAN 1 1268.648 0.91 97260 9160 3 1268.644683 423.8899 Myosin-10 OS=Homo sapiens OX=9606 GN=MYH10 PE=1 SV=3 6.11 1935.9 - 6.08E+06 - - - -2.6028 - 1.898 0.324 - 225.1 1 2 1 -0.0033 11 0 0 0 6.83E+07 7.49E+07 - - - 3.9718 0.9986 221125_WJC_METTL3_EV_vs_WT_F07.09161.09161.3 0.00683 Dec-40 R.QAEEQIEHLQR[166.11].K "sp|O75150|BRE1B_HUMAN,tr|H3BP71|H3BP71_HUMAN" 2 1389.6876 12.78 97261 9161 3 1389.684123 464.2365 E3 ubiquitin-protein ligase BRE1B OS=Homo sapiens OX=9606 GN=RNF40 PE=1 SV=5 4.75 1935.9 - 1.09E+06 - - - -2.5099 - 2.047 0.289 - 279.1 1 2 0 -0.0035 11 0 0 0 2.43E+08 1.90E+07 - - - 3.7962 0.9858 221125_WJC_METTL3_EV_vs_WT_F07.09162.09162.3 0.0134 Oct-36 R.TKFETEQALR.L "sp|Q04695|K1C17_HUMAN,sp|P08727|K1C19_HUMAN,tr|C9JM50|C9JM50_HUMAN,tr|F5GWP8|F5GWP8_HUMAN" 4 1221.6354 1.31 97262 9162 3 1221.638108 408.2191 "Keratin, type I cytoskeletal 17 OS=Homo sapiens OX=9606 GN=KRT17 PE=1 SV=2" 5.81 1936 - 1.92E+06 - - - 2.2568 - 1.727 0.265 - 149.8 1 2 1 0.0028 10 0 0 0 7.46E+07 5.69E+07 - - - 3.0894 1 221125_WJC_METTL3_EV_vs_WT_F07.09166.09166.3 6.89E-07 13/48 K.TVIK[136.11]PESC[160.03]VPC[160.03]GK[136.11].R "sp|Q9H0H5|RGAP1_HUMAN,tr|F8VRL2|F8VRL2_HUMAN" 2 1489.7604 1.68 97266 9166 3 1489.759842 497.5941 Rac GTPase-activating protein 1 OS=Homo sapiens OX=9606 GN=RACGAP1 PE=1 SV=1 7.72 1936.4 - 756891 - - - -0.3551 - 2.546 0.5 - 154.4 1 2 0 -0.0005 13 0 0 0 1.64E+07 9.77E+06 - - - 6.6481 0.9897 221125_WJC_METTL3_EV_vs_WT_F07.09168.09168.2 0.0298 20-Jul R.QQLLEQQQPQK.A "sp|Q9UPN6|SCAF8_HUMAN,tr|A0A0A0MT33|A0A0A0MT33_HUMAN" 2 1366.7205 0.19 97268 9168 2 1366.726251 684.3675 SR-related and CTD-associated factor 8 OS=Homo sapiens OX=9606 GN=SCAF8 PE=1 SV=1 6 1936.7 - 232986 - - - 4.224 - 1.507 0.311 - 147.7 1 2 0 0.0058 11 0 0 0 4.34E+06 2.29E+07 - - - 2.4457 0.9995 221125_WJC_METTL3_EV_vs_WT_F07.09171.09171.3 0.00121 Sep-44 R.RGVTIKPTVDDD.- "sp|Q2VIR3|IF2GL_HUMAN,sp|P41091|IF2G_HUMAN" 2 1314.6779 0.97 97269 9171 3 1314.676907 439.2333 Eukaryotic translation initiation factor 2 subunit 3B OS=Homo sapiens OX=9606 GN=EIF2S3B PE=2 SV=2 4.68 1937.1 - 4.08E+06 - - - -0.7895 - 1.437 0.388 - 91.2 1 2 0 -0.001 12 0 0 0 6.56E+07 6.79E+07 - - - 3.8705 0.9994 221125_WJC_METTL3_EV_vs_WT_F07.09172.09172.3 0.00114 Sep-44 R.R[166.11]GVTIK[136.11]PTVDDD.- "sp|Q2VIR3|IF2GL_HUMAN,sp|P41091|IF2G_HUMAN" 2 1332.7004 0.97 97270 9172 3 1332.699915 445.2407 Eukaryotic translation initiation factor 2 subunit 3B OS=Homo sapiens OX=9606 GN=EIF2S3B PE=2 SV=2 4.68 1937.1 - 4.24E+06 - - - -0.3752 - 1.547 0.357 - 125 1 2 0 -0.0005 12 0 0 0 6.56E+07 6.79E+07 - - - 3.7295 0.9895 221125_WJC_METTL3_EV_vs_WT_F07.09176.09176.2 0.25 18-Oct R.TKFETEQALR.L "sp|Q04695|K1C17_HUMAN,sp|P08727|K1C19_HUMAN,tr|C9JM50|C9JM50_HUMAN,tr|F5GWP8|F5GWP8_HUMAN" 4 1221.6354 4.37 97274 9176 2 1221.637914 611.825 "Keratin, type I cytoskeletal 17 OS=Homo sapiens OX=9606 GN=KRT17 PE=1 SV=2" 5.81 1937.5 - 649789 - - - 2.098 - 1.87 0.341 - 239.8 1 2 1 0.0026 10 0 0 0 1.93E+07 4.43E+06 - - - 3.306 0.9999 221125_WJC_METTL3_EV_vs_WT_F07.09179.09179.2 2.84E-05 18-Oct R.K[136.11]IYFTDSSSK[136.11].W "sp|Q9HDC9|APMAP_HUMAN,tr|H0Y512|H0Y512_HUMAN" 2 1190.6154 1.31 97277 9179 2 1190.616205 596.315 Adipocyte plasma membrane-associated protein OS=Homo sapiens OX=9606 GN=APMAP PE=1 SV=2 8.5 1937.9 - 268781 - - - 0.6728 - 2.158 0.515 - 328.7 1 2 0 0.0008 10 0 0 0 9.66E+06 7.39E+06 - - - 4.9916 0.9996 221125_WJC_METTL3_EV_vs_WT_F07.09186.09186.3 5.57E-05 14/36 R.SER[166.11]EEVSSWR[166.11].R sp|Q14152|EIF3A_HUMAN 1 1283.6009 0.75 97281 9186 3 1283.599489 428.8742 Eukaryotic translation initiation factor 3 subunit A OS=Homo sapiens OX=9606 GN=EIF3A PE=1 SV=1 4.78 1938.7 - 1.13E+06 - - - -1.1133 - 2.237 0.401 - 395 1 2 1 -0.0014 10 0 0 0 1.90E+07 2.53E+07 - - - 5.3617 0.9998 221125_WJC_METTL3_EV_vs_WT_F07.09188.09188.2 4.11E-05 18-Nov R.KIYFTDSSSK.W "sp|Q9HDC9|APMAP_HUMAN,tr|H0Y512|H0Y512_HUMAN" 2 1174.587 1.31 97282 9188 2 1174.588414 588.3008 Adipocyte plasma membrane-associated protein OS=Homo sapiens OX=9606 GN=APMAP PE=1 SV=2 8.5 1938.9 - 440239 - - - 1.2004 - 2.136 0.541 - 384.3 1 2 0 0.0014 10 0 0 0 9.66E+06 7.39E+06 - - - 5.1548 0.9978 221125_WJC_METTL3_EV_vs_WT_F07.09189.09189.3 0.0555 Sep-52 R.SPESRPSVVYPSTK.F "sp|P42694|HELZ_HUMAN,tr|J3QS41|J3QS41_HUMAN" 2 1532.7835 1.79 97283 9189 3 1532.784285 511.9351 Probable helicase with zinc finger domain OS=Homo sapiens OX=9606 GN=HELZ PE=1 SV=2 8.31 1939.1 - 278437 - - - 0.5304 - 1.794 0.239 - 97.3 1 2 0 0.0008 14 0 0 0 1.23E+07 6.90E+06 - - - 2.7576 0.9954 221125_WJC_METTL3_EV_vs_WT_F07.09190.09190.2 0.00445 22-Sep K.IKGEELSEANVR.L "sp|Q14203|DCTN1_HUMAN,tr|A0A804CDA6|A0A804CDA6_HUMAN,tr|E7EX90|E7EX90_HUMAN,tr|A0A7P0Z4C3|A0A7P0Z4C3_HUMAN" 4 1343.7045 2.47 97284 9190 2 1343.705665 672.8595 Dynactin subunit 1 OS=Homo sapiens OX=9606 GN=DCTN1 PE=1 SV=3 4.79 1939.2 - 234870 - - - 0.8715 - 1.95 0.361 - 168.3 1 2 1 0.0012 12 0 0 0 5.39E+06 2.18E+06 - - - 3.4642 1 221125_WJC_METTL3_EV_vs_WT_F07.09199.09199.3 1.27E-09 16/48 K.QPC[160.03]QPPPVC[160.03]PTPK.C "sp|P22531|SPR2E_HUMAN,sp|P35326|SPR2A_HUMAN,sp|P22532|SPR2D_HUMAN,sp|P35325|SPR2B_HUMAN,sp|Q9BYE4|SPR2G_HUMAN" 5 1504.7167 2.79 97291 9199 3 1504.715729 502.5795 Small proline-rich protein 2E OS=Homo sapiens OX=9606 GN=SPRR2E PE=2 SV=2 8.06 1940.3 - 849855 - - - -0.6161 - 2.79 0.514 - 441.8 1 2 0 -0.0009 13 0 0 0 9.78E+07 3.50E+07 - - - 7.0522 0.9963 221125_WJC_METTL3_EV_vs_WT_F07.09200.09200.3 0.00213 Sep-32 K.QKDYDFEER.M sp|Q96NC0|ZMAT2_HUMAN 1 1228.536 0.82 97292 9200 3 1228.536915 410.5193 Zinc finger matrin-type protein 2 OS=Homo sapiens OX=9606 GN=ZMAT2 PE=1 SV=1 4.32 1940.3 - 751042 - - - 0.7196 - 1.807 0.282 - 125.5 1 2 1 0.0009 9 0 0 0 2.87E+07 3.51E+07 - - - 3.4669 0.9998 221125_WJC_METTL3_EV_vs_WT_F07.09204.09204.2 0.000265 20-Oct R.DNTSVYHISGK[136.11].K "sp|Q9NTJ3|SMC4_HUMAN,tr|E9PD53|E9PD53_HUMAN,tr|C9JR83|C9JR83_HUMAN,tr|C9JVD8|C9JVD8_HUMAN,tr|C9J578|C9J578_HUMAN,tr|C9J9E4|C9J9E4_HUMAN" 6 1227.5975 0.79 97296 9204 2 1227.598507 614.806 Structural maintenance of chromosomes protein 4 OS=Homo sapiens OX=9606 GN=SMC4 PE=1 SV=2 6.74 1940.9 - 211105 - - - 0.8073 - 2.06 0.488 - 379.4 1 2 0 0.001 11 0 0 0 4.23E+06 5.38E+06 - - - 4.6001 0.9999 221125_WJC_METTL3_EV_vs_WT_F07.09206.09206.3 0.00949 13/40 R.DHPLPEVAHVK[136.11].H "sp|P13073|COX41_HUMAN,tr|Q86WV2|Q86WV2_HUMAN,tr|H3BN72|H3BN72_HUMAN,tr|H3BPG0|H3BPG0_HUMAN,tr|H3BNV9|H3BNV9_HUMAN" 5 1248.6706 1.71 97297 9206 3 1248.672953 417.2308 "Cytochrome c oxidase subunit 4 isoform 1, mitochondrial OS=Homo sapiens OX=9606 GN=COX4I1 PE=1 SV=1" 5.99 1941.1 - 7.89E+06 - - - 1.8676 - 2.517 0.458 - 273.3 1 2 0 0.0023 11 0 0 0 2.73E+08 1.59E+08 - - - 6.2679 0.9993 221125_WJC_METTL3_EV_vs_WT_F07.09210.09210.2 0.00269 22-Oct R.R[166.11]GVTIK[136.11]PTVDDD.- "sp|Q2VIR3|IF2GL_HUMAN,sp|P41091|IF2G_HUMAN" 2 1332.7004 0.92 97301 9210 2 1332.699189 667.3575 Eukaryotic translation initiation factor 2 subunit 3B OS=Homo sapiens OX=9606 GN=EIF2S3B PE=2 SV=2 4.68 1941.4 - 940514 - - - -0.9199 - 1.387 0.391 - 201.3 1 2 0 -0.0012 12 0 0 0 2.29E+07 2.49E+07 - - - 2.7893 0.9935 221125_WJC_METTL3_EV_vs_WT_F07.09211.09211.2 0.0866 20-Nov K.SDQSRLDSELK.N sp|P04264|K2C1_HUMAN 1 1276.6259 999 97302 9211 2 1276.624801 639.3202 "Keratin, type II cytoskeletal 1 OS=Homo sapiens OX=9606 GN=KRT1 PE=1 SV=6" 4.56 1941.6 - 712676 - - - -0.8679 - 2.069 0.27 - 368.7 1 2 1 -0.0011 11 0 0 0 2.60E+07 0.00E+00 - - - 3.0018 0.9999 221125_WJC_METTL3_EV_vs_WT_F07.09212.09212.3 0.249 13/52 R.HYPAPYGPGPGQDK.G sp|P17509|HXB6_HUMAN 1 1482.6892 1.26 97303 9212 3 1482.690497 495.237 Homeobox protein Hox-B6 OS=Homo sapiens OX=9606 GN=HOXB6 PE=1 SV=4 6.74 1941.7 - 708638 - - - 0.8896 - 2.301 0.369 - 215.5 1 2 0 0.0013 14 0 0 0 1.41E+07 1.12E+07 - - - 4.8683 0.9983 221125_WJC_METTL3_EV_vs_WT_F07.09213.09213.2 0.000102 16-Aug K.QK[136.11]DYDFEER[166.11].M sp|Q96NC0|ZMAT2_HUMAN 1 1246.5585 0.74 97304 9213 2 1246.558246 624.2865 Zinc finger matrin-type protein 2 OS=Homo sapiens OX=9606 GN=ZMAT2 PE=1 SV=1 4.32 1941.8 - 338809 - - - -0.2046 - 1.745 0.517 - 257.6 1 2 1 -0.0003 9 0 0 0 3.40E+06 4.57E+06 - - - 4.4702 0.9953 221125_WJC_METTL3_EV_vs_WT_F07.09216.09216.3 0.125 Sep-40 K.SDQSRLDSELK.N sp|P04264|K2C1_HUMAN 1 1276.6259 31.26 97305 9216 3 1276.624006 426.5492 "Keratin, type II cytoskeletal 1 OS=Homo sapiens OX=9606 GN=KRT1 PE=1 SV=6" 4.56 1942.2 - 7.14E+06 - - - -1.4906 - 1.837 0.288 - 142.9 1 2 1 -0.0019 11 0 0 0 1.28E+08 4.11E+06 - - - 3.478 0.9944 221125_WJC_METTL3_EV_vs_WT_F07.09218.09218.3 0.223 Nov-56 R.FR[166.11]PAGAAPR[166.11]PPPK[136.11]PM.- "sp|Q5JNZ5|RS26L_HUMAN,sp|P62854|RS26_HUMAN" 2 1616.8968 0.85 97307 9218 3 1616.892636 539.9729 Putative 40S ribosomal protein S26-like 1 OS=Homo sapiens OX=9606 GN=RPS26P11 PE=5 SV=1 12.01 1942.4 - 344040 - - - -2.5611 - 1.582 0.275 - 109.4 1 2 0 -0.0041 15 0 0 0 5.13E+06 6.06E+06 - - - 2.8017 0.9268 221125_WJC_METTL3_EV_vs_WT_F07.09225.09225.3 0.0702 Jul-36 R.YRNPVSQC[160.03]MR.G "sp|Q13148|TADBP_HUMAN,tr|A0A087WX29|A0A087WX29_HUMAN,tr|K7EJ99|K7EJ99_HUMAN,tr|G3V162|G3V162_HUMAN,tr|A0A0A0MSV7|A0A0A0MSV7_HUMAN,tr|A0A087WYY0|A0A087WYY0_HUMAN,tr|K7EN94|K7EN94_HUMAN,tr|A0A0A0N0M3|A0A0A0N0M3_HUMAN,tr|B1AKP7|B1AKP7_HUMAN,tr|K7EJM5|K7EJM5_HUMAN,tr|A0A087X260|A0A087X260_HUMAN" 11 1309.602 0.4 97312 9225 3 1309.602159 437.5413 TAR DNA-binding protein 43 OS=Homo sapiens OX=9606 GN=TARDBP PE=1 SV=1 9.5 1943.2 - 3.28E+06 - - - 0.152 - 1.271 0.202 - 93.2 1 2 1 0.0002 10 0 0 0 1.64E+08 4.04E+08 - - - 1.4924 1 221125_WJC_METTL3_EV_vs_WT_F07.09226.09226.2 0.000133 16/26 R.MVSALQQQQQQQQR.Q "sp|Q9UPQ9|TNR6B_HUMAN,tr|H0Y720|H0Y720_HUMAN" 2 1699.8424 3.07 97313 9226 2 1699.838769 850.9285 Trinucleotide repeat-containing gene 6B protein OS=Homo sapiens OX=9606 GN=TNRC6B PE=1 SV=4 9.5 1943.3 - 513730 - - - -2.1367 - 3.373 0.635 - 1324.9 1 2 0 -0.0036 14 0 0 0 7.66E+06 2.50E+06 - - - 6.781 0.9725 221125_WJC_METTL3_EV_vs_WT_F07.09227.09227.4 0.198 13/84 R.FRPAGAAPRPPPKPM.- "sp|Q5JNZ5|RS26L_HUMAN,sp|P62854|RS26_HUMAN" 2 1588.866 1.02 97314 9227 4 1588.866437 398.2238 Putative 40S ribosomal protein S26-like 1 OS=Homo sapiens OX=9606 GN=RPS26P11 PE=5 SV=1 12.01 1943.4 - 492328 - - - 0.2518 - 1.756 0.16 - 100.4 1 2 0 0.0004 15 0 0 0 6.47E+07 6.35E+07 - - - 0.82 0.9935 221125_WJC_METTL3_EV_vs_WT_F07.09228.09228.2 0.868 22-Jul R.RGVTIKPTVDDD.- "sp|Q2VIR3|IF2GL_HUMAN,sp|P41091|IF2G_HUMAN" 2 1314.6779 0.87 97315 9228 2 1314.678674 658.3462 Eukaryotic translation initiation factor 2 subunit 3B OS=Homo sapiens OX=9606 GN=EIF2S3B PE=2 SV=2 4.68 1943.5 - 424966 - - - 0.5545 - 1.183 0.204 - 102.3 1 2 0 0.0007 12 0 0 0 2.18E+07 2.49E+07 - - - 0.9897 0.9999 221125_WJC_METTL3_EV_vs_WT_F07.09229.09229.2 0.000109 26-Dec R.MVSALQQQQQQQQR[166.11].Q "sp|Q9UPQ9|TNR6B_HUMAN,tr|H0Y720|H0Y720_HUMAN" 2 1709.8507 3.07 97316 9229 2 1709.849461 855.9326 Trinucleotide repeat-containing gene 6B protein OS=Homo sapiens OX=9606 GN=TNRC6B PE=1 SV=4 9.5 1943.7 - 174085 - - - -0.7077 - 2.621 0.556 - 428.5 1 2 0 -0.0012 14 0 0 0 7.66E+06 2.50E+06 - - - 5.5652 0.9985 221125_WJC_METTL3_EV_vs_WT_F07.09237.09237.2 2.36E-05 18-Dec R.YRNPVSQC[160.03]MR.G "sp|Q13148|TADBP_HUMAN,tr|A0A087WX29|A0A087WX29_HUMAN,tr|K7EJ99|K7EJ99_HUMAN,tr|G3V162|G3V162_HUMAN,tr|A0A0A0MSV7|A0A0A0MSV7_HUMAN,tr|A0A087WYY0|A0A087WYY0_HUMAN,tr|K7EN94|K7EN94_HUMAN,tr|A0A0A0N0M3|A0A0A0N0M3_HUMAN,tr|B1AKP7|B1AKP7_HUMAN,tr|K7EJM5|K7EJM5_HUMAN,tr|A0A087X260|A0A087X260_HUMAN" 11 1309.602 1.04 97322 9237 2 1309.601513 655.8083 TAR DNA-binding protein 43 OS=Homo sapiens OX=9606 GN=TARDBP PE=1 SV=1 9.5 1944.5 - 490597 - - - -0.3413 - 2.146 0.482 - 228.5 1 2 1 -0.0004 10 0 0 0 2.38E+07 2.29E+07 - - - 4.7324 0.9906 221125_WJC_METTL3_EV_vs_WT_F07.09240.09240.2 0.185 18-Oct R.YR[166.11]NPVSQC[160.03]MR[166.11].G "sp|Q13148|TADBP_HUMAN,tr|A0A087WX29|A0A087WX29_HUMAN,tr|K7EJ99|K7EJ99_HUMAN,tr|G3V162|G3V162_HUMAN,tr|A0A0A0MSV7|A0A0A0MSV7_HUMAN,tr|A0A087WYY0|A0A087WYY0_HUMAN,tr|K7EN94|K7EN94_HUMAN,tr|A0A0A0N0M3|A0A0A0N0M3_HUMAN,tr|B1AKP7|B1AKP7_HUMAN,tr|K7EJM5|K7EJM5_HUMAN,tr|A0A087X260|A0A087X260_HUMAN" 11 1329.6185 1.04 97325 9240 2 1329.617835 665.8165 TAR DNA-binding protein 43 OS=Homo sapiens OX=9606 GN=TARDBP PE=1 SV=1 9.5 1944.9 - 364915 - - - -0.5001 - 1.76 0.261 - 147.4 1 2 1 -0.0007 10 0 0 0 2.38E+07 2.29E+07 - - - 2.5465 0.9996 221125_WJC_METTL3_EV_vs_WT_F07.09244.09244.3 0.00748 Nov-44 K.LPQTSDDEKKDF.- sp|Q9GZT3|SLIRP_HUMAN 1 1421.6674 1.37 97327 9244 3 1421.66571 474.8964 "SRA stem-loop-interacting RNA-binding protein, mitochondrial OS=Homo sapiens OX=9606 GN=SLIRP PE=1 SV=1" 4.23 1945.5 - 6.99E+06 - - - -1.2162 - 1.844 0.458 - 105.3 1 2 1 -0.0017 12 0 0 0 2.19E+09 1.60E+09 - - - 5.342 1 221125_WJC_METTL3_EV_vs_WT_F07.09247.09247.3 6.53E-08 21/56 R.VGQAVDVVGQAGK[136.11]PK[136.11].T sp|Q13200|PSMD2_HUMAN 1 1467.838 0.59 97330 9247 3 1467.83606 490.2866 26S proteasome non-ATPase regulatory subunit 2 OS=Homo sapiens OX=9606 GN=PSMD2 PE=1 SV=3 8.56 1945.7 - 1.53E+06 - - - -1.3401 - 3.651 0.574 - 659.5 1 2 0 -0.002 15 0 0 0 8.21E+07 1.40E+08 - - - 8.3181 0.9907 221125_WJC_METTL3_EV_vs_WT_F07.09249.09249.2 6.79E-05 12-Oct L.PEVAHVK[136.11].H "sp|P13073|COX41_HUMAN,tr|Q86WV2|Q86WV2_HUMAN,tr|H3BN72|H3BN72_HUMAN,tr|H3BPG0|H3BPG0_HUMAN,tr|H3BNV9|H3BNV9_HUMAN" 5 786.4479 1.25 97332 9249 2 786.44722 394.2312 "Cytochrome c oxidase subunit 4 isoform 1, mitochondrial OS=Homo sapiens OX=9606 GN=COX4I1 PE=1 SV=1" 7.17 1945.9 - 1.18E+06 - - - -0.913 - 1.818 0.505 - 259.6 1 1 0 -0.0007 7 0 0 0 2.67E+07 2.13E+07 - - - 4.6647 0.9997 221125_WJC_METTL3_EV_vs_WT_F07.09252.09252.3 0.0507 Aug-40 R.RSTSSFSC[160.03]LSR.H sp|P35908|K22E_HUMAN 1 1286.6037 0.79 97335 9252 3 1286.604963 429.8752 "Keratin, type II cytoskeletal 2 epidermal OS=Homo sapiens OX=9606 GN=KRT2 PE=1 SV=2" 10.35 1946.1 - 899575 - - - 0.9552 - 1.649 0.378 - 83.7 1 2 0 0.0012 11 0 0 0 8.16E+06 1.04E+07 - - - 4.1749 0.9999 221125_WJC_METTL3_EV_vs_WT_F07.09253.09253.3 2.43E-05 17/56 R.LQAAYAGDKADDIQK.R "sp|Q01082|SPTB2_HUMAN,tr|A0A087WUZ3|A0A087WUZ3_HUMAN" 2 1605.7999 1.76 97336 9253 3 1605.79852 536.2739 "Spectrin beta chain, non-erythrocytic 1 OS=Homo sapiens OX=9606 GN=SPTBN1 PE=1 SV=2" 4.43 1946.2 - 888626 - - - -0.8289 - 3.299 0.452 - 310.3 1 2 1 -0.0013 15 0 0 0 1.21E+07 6.89E+06 - - - 6.6936 0.9991 221125_WJC_METTL3_EV_vs_WT_F07.09254.09254.3 3.35E-05 16/56 R.LQAAYAGDK[136.11]ADDIQK[136.11].R "sp|Q01082|SPTB2_HUMAN,tr|A0A087WUZ3|A0A087WUZ3_HUMAN" 2 1621.8283 1.76 97337 9254 3 1621.823476 541.6167 "Spectrin beta chain, non-erythrocytic 1 OS=Homo sapiens OX=9606 GN=SPTBN1 PE=1 SV=2" 4.43 1946.4 - 780767 - - - -2.9442 - 2.869 0.404 - 223.5 1 2 1 -0.0048 15 0 0 0 1.21E+07 6.89E+06 - - - 5.7931 0.9963 221125_WJC_METTL3_EV_vs_WT_F07.09256.09256.2 0.00136 28-Nov K.AINGPTSASGDDISK[136.11].L "sp|P51114|FXR1_HUMAN,tr|H7C4S4|H7C4S4_HUMAN,tr|B4DXZ6|B4DXZ6_HUMAN" 3 1439.6984 0.35 97339 9256 2 1439.699295 720.8565 Fragile X mental retardation syndrome-related protein 1 OS=Homo sapiens OX=9606 GN=FXR1 PE=1 SV=3 4.21 1946.6 - 619413 - - - 0.655 - 2.096 0.095 - 226.8 2 2 0 0.0009 15 0 0 0 2.35E+07 6.78E+07 - - - 1.4273 0.9998 221125_WJC_METTL3_EV_vs_WT_F07.09259.09259.2 2.55E-06 24-Sep K.GPGEVAGTVTGQK.R "sp|Q86U44|MTA70_HUMAN,tr|F5H6D8|F5H6D8_HUMAN,tr|H0YFV6|H0YFV6_HUMAN,tr|B4DTN4|B4DTN4_HUMAN" 4 1199.6146 0.02 97342 9259 2 1199.613266 600.8146 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 6 1947 - 249128 - - - -1.1254 - 2.202 0.511 - 240.1 1 2 0 -0.0014 13 0 0 0 6.92E+06 4.10E+08 - - - 4.8408 1 221125_WJC_METTL3_EV_vs_WT_F07.09265.09265.2 3.12E-05 15/28 K.GSC[160.03]GIGGGIGGGSSR.L "sp|P02533|K1C14_HUMAN,sp|P08779|K1C16_HUMAN,tr|K7ENV3|K7ENV3_HUMAN" 3 1277.5782 999 97346 9265 2 1277.576881 639.7964 "Keratin, type I cytoskeletal 14 OS=Homo sapiens OX=9606 GN=KRT14 PE=1 SV=4" 8.25 1947.8 - 1.47E+07 - - - -1.0692 - 2.646 0.64 - 442.9 1 2 0 -0.0014 15 0 0 0 9.31E+09 0.00E+00 - - - 6.1599 0.9989 221125_WJC_METTL3_EV_vs_WT_F07.09266.09266.3 0.00125 15/36 K.EEVKLEAHIR.V "sp|O00425|IF2B3_HUMAN,sp|Q9Y6M1|IF2B2_HUMAN,tr|F8W930|F8W930_HUMAN" 3 1222.667 7.18 97347 9266 3 1222.667989 408.5629 Insulin-like growth factor 2 mRNA-binding protein 3 OS=Homo sapiens OX=9606 GN=IGF2BP3 PE=1 SV=2 5.5 1947.9 - 3.01E+06 - - - 0.8203 - 2.337 0.307 - 394.3 1 2 1 0.001 10 0 0 0 3.11E+07 4.33E+06 - - - 4.4415 1 221125_WJC_METTL3_EV_vs_WT_F07.09269.09269.2 4.96E-09 17/22 K.LPQTSDDEKKDF.- sp|Q9GZT3|SLIRP_HUMAN 1 1421.6674 1.28 97350 9269 2 1421.66399 711.841 "SRA stem-loop-interacting RNA-binding protein, mitochondrial OS=Homo sapiens OX=9606 GN=SLIRP PE=1 SV=1" 4.23 1948.1 - 2.59E+06 - - - -2.426 - 2.605 0.619 - 928 1 2 1 -0.0034 12 0 0 0 2.44E+08 1.91E+08 - - - 6.131 0.9998 221125_WJC_METTL3_EV_vs_WT_F07.09270.09270.2 0.000173 16-Sep K.ESEFDDEPK.F "sp|Q9Y2W1|TR150_HUMAN,tr|A0A3B3ITZ9|A0A3B3ITZ9_HUMAN" 2 1094.4404 8.08 97351 9270 2 1094.439414 548.2275 Thyroid hormone receptor-associated protein 3 OS=Homo sapiens OX=9606 GN=THRAP3 PE=1 SV=2 3.83 1948.2 - 978579 - - - -0.9009 - 1.601 0.541 - 342.3 1 2 0 -0.001 9 0 0 0 1.79E+07 2.21E+06 - - - 4.3981 0.9999 221125_WJC_METTL3_EV_vs_WT_F07.09272.09272.3 0.000547 Nov-32 K.HLTDAYFK[136.11]K[136.11].K sp|Q02878|RL6_HUMAN 1 1137.6153 0.001 97353 9272 3 1137.614189 380.2124 60S ribosomal protein L6 OS=Homo sapiens OX=9606 GN=RPL6 PE=1 SV=3 8.51 1948.5 - 530848 - - - -1.0162 - 1.611 0.436 - 187.5 1 2 0 -0.0012 9 0 0 0 0.00E+00 6.10E+06 - - - 4.8378 0.9306 221125_WJC_METTL3_EV_vs_WT_F07.09273.09273.3 0.103 Aug-36 K.AREESWGPPR.E sp|Q14152|EIF3A_HUMAN 1 1183.5734 0.96 97354 9273 3 1183.570247 395.5317 Eukaryotic translation initiation factor 3 subunit A OS=Homo sapiens OX=9606 GN=EIF3A PE=1 SV=1 6.19 1948.6 - 413833 - - - -2.6809 - 1.491 0.222 - 139.3 1 2 1 -0.0032 10 0 0 0 5.38E+06 5.63E+06 - - - 2.1808 0.9992 221125_WJC_METTL3_EV_vs_WT_F07.09277.09277.3 0.00164 13/44 K.LPQTSDDEK[136.11]K[136.11]DF.- sp|Q9GZT3|SLIRP_HUMAN 1 1437.6958 1.36 97356 9277 3 1437.692616 480.2392 "SRA stem-loop-interacting RNA-binding protein, mitochondrial OS=Homo sapiens OX=9606 GN=SLIRP PE=1 SV=1" 4.23 1949.1 - 4.78E+07 - - - -2.2418 - 1.859 0.463 - 171.9 1 2 1 -0.0032 12 0 0 0 2.18E+09 1.60E+09 - - - 5.4198 0.9999 221125_WJC_METTL3_EV_vs_WT_F07.09278.09278.2 3.81E-06 24-Oct K.QPC[160.03]QPPPVC[160.03]PTPK.C "sp|P22531|SPR2E_HUMAN,sp|P35326|SPR2A_HUMAN,sp|P22532|SPR2D_HUMAN,sp|P35325|SPR2B_HUMAN,sp|Q9BYE4|SPR2G_HUMAN" 5 1504.7167 545.84 97357 9278 2 1504.715861 753.3656 Small proline-rich protein 2E OS=Homo sapiens OX=9606 GN=SPRR2E PE=2 SV=2 8.06 1949.1 - 5.73E+06 - - - -0.5283 - 2.08 0.522 - 269 1 2 0 -0.0008 13 0 0 0 2.11E+08 3.86E+05 - - - 4.7759 0.9999 221125_WJC_METTL3_EV_vs_WT_F07.09280.09280.3 1.55E-06 19/52 K.GLNTDELGQKEEAK.N sp|Q8N0X7|SPART_HUMAN 1 1530.7526 1.09 97359 9280 3 1530.751057 511.2581 Spartin OS=Homo sapiens OX=9606 GN=SPART PE=1 SV=1 4.41 1949.2 - 4.12E+06 - - - -0.9858 - 3.23 0.546 - 335.4 1 2 1 -0.0015 14 0 0 0 1.55E+08 1.42E+08 - - - 7.7429 0.9999 221125_WJC_METTL3_EV_vs_WT_F07.09285.09285.3 1.90E-05 15/52 K.GLNTDELGQK[136.11]EEAK[136.11].N sp|Q8N0X7|SPART_HUMAN 1 1546.781 1.09 97362 9285 3 1546.778422 516.6009 Spartin OS=Homo sapiens OX=9606 GN=SPART PE=1 SV=1 4.41 1949.8 - 4.87E+06 - - - -1.6447 - 2.938 0.576 - 193.3 1 2 1 -0.0025 14 0 0 0 1.55E+08 1.42E+08 - - - 7.8252 1 221125_WJC_METTL3_EV_vs_WT_F07.09286.09286.3 9.96E-09 20/56 R.VGQAVDVVGQAGKPK.T sp|Q13200|PSMD2_HUMAN 1 1451.8096 0.59 97363 9286 3 1451.807083 484.9438 26S proteasome non-ATPase regulatory subunit 2 OS=Homo sapiens OX=9606 GN=PSMD2 PE=1 SV=3 8.56 1949.8 - 4.40E+06 - - - -1.7523 - 3.627 0.571 - 615.9 1 2 0 -0.0025 15 0 0 0 8.21E+07 1.40E+08 - - - 8.2673 1 221125_WJC_METTL3_EV_vs_WT_F07.09288.09288.3 1.67E-06 16/48 R.YESHPVC[160.03]ADLQAK.L "sp|Q9NX63|MIC19_HUMAN,tr|C9JRZ6|C9JRZ6_HUMAN" 2 1516.698 0.7 97365 9288 3 1516.696954 506.5733 MICOS complex subunit MIC19 OS=Homo sapiens OX=9606 GN=CHCHD3 PE=1 SV=1 5.32 1949.9 - 2.84E+06 - - - -0.7081 - 2.765 0.595 - 190.9 1 2 0 -0.0011 13 0 0 0 4.36E+08 6.24E+08 - - - 7.9309 1 221125_WJC_METTL3_EV_vs_WT_F07.09289.09289.3 4.42E-05 17/44 R.VTAIHIDPATHR[166.11].Q "sp|P49327|FAS_HUMAN,tr|A0A0U1RQF0|A0A0U1RQF0_HUMAN" 2 1339.7236 0.61 97366 9289 3 1339.722571 447.5818 Fatty acid synthase OS=Homo sapiens OX=9606 GN=FASN PE=1 SV=3 6.89 1949.9 - 1.91E+06 - - - -0.7703 - 2.72 0.467 - 457.2 1 2 0 -0.001 12 0 0 0 5.32E+07 8.67E+07 - - - 6.5199 1 221125_WJC_METTL3_EV_vs_WT_F07.09291.09291.2 7.81E-09 16/28 R.VGQAVDVVGQAGK[136.11]PK[136.11].T sp|Q13200|PSMD2_HUMAN 1 1467.838 0.5 97368 9291 2 1467.835082 734.9263 26S proteasome non-ATPase regulatory subunit 2 OS=Homo sapiens OX=9606 GN=PSMD2 PE=1 SV=3 8.56 1950.2 - 504975 - - - -2.0064 - 3.351 0.638 - 1078.3 1 2 0 -0.0029 15 0 0 0 5.45E+06 1.09E+07 - - - 6.7254 0.9997 221125_WJC_METTL3_EV_vs_WT_F07.09296.09296.3 1.47E-05 17/56 R.APQEFMTSHSEAGSR.L sp|Q9BRR6|ADPGK_HUMAN 1 1633.7155 1.04 97371 9296 3 1633.709174 545.5791 ADP-dependent glucokinase OS=Homo sapiens OX=9606 GN=ADPGK PE=1 SV=1 5.4 1950.9 - 701313 - - - -3.8532 - 2.304 0.475 - 207.4 1 2 0 -0.0063 15 0 0 0 6.48E+07 6.21E+07 - - - 6.0119 1 221125_WJC_METTL3_EV_vs_WT_F07.09297.09297.2 4.35E-07 13/26 K.GLNTDELGQK[136.11]EEAK[136.11].N sp|Q8N0X7|SPART_HUMAN 1 1546.781 0.97 97372 9297 2 1546.780913 774.3978 Spartin OS=Homo sapiens OX=9606 GN=SPART PE=1 SV=1 4.41 1951 - 653860 - - - -0.0343 - 2.914 0.624 - 472.3 1 2 1 -0.0001 14 0 0 0 1.13E+07 1.16E+07 - - - 6.3338 1 221125_WJC_METTL3_EV_vs_WT_F07.09302.09302.3 6.32E-08 Dec-44 K.EDVFVHQTAIK[136.11]K[136.11].N "sp|P67809|YBOX1_HUMAN,sp|P16989|YBOX3_HUMAN,tr|H0Y449|H0Y449_HUMAN,tr|A0A0D9SEI8|A0A0D9SEI8_HUMAN" 4 1429.79 1.04 97375 9302 3 1429.787583 477.6039 Y-box-binding protein 1 OS=Homo sapiens OX=9606 GN=YBX1 PE=1 SV=3 6.85 1951.6 - 4.98E+06 - - - -1.7009 - 2.352 0.568 - 178.5 1 2 0 -0.0024 12 0 0 0 8.06E+07 7.76E+07 - - - 7.2426 1 221125_WJC_METTL3_EV_vs_WT_F07.09303.09303.3 1.35E-07 13/44 K.EDVFVHQTAIKK.N "sp|P67809|YBOX1_HUMAN,sp|P16989|YBOX3_HUMAN,tr|H0Y449|H0Y449_HUMAN,tr|A0A0D9SEI8|A0A0D9SEI8_HUMAN" 4 1413.7616 1.04 97376 9303 3 1413.76 472.2611 Y-box-binding protein 1 OS=Homo sapiens OX=9606 GN=YBX1 PE=1 SV=3 6.85 1951.7 - 5.09E+06 - - - -1.1423 - 2.373 0.531 - 237.7 1 2 0 -0.0016 12 0 0 0 8.06E+07 7.76E+07 - - - 6.855 0.9998 221125_WJC_METTL3_EV_vs_WT_F07.09305.09305.2 5.09E-05 13/24 K.GPGEVAGTVTGQK[136.11].R "sp|Q86U44|MTA70_HUMAN,tr|F5H6D8|F5H6D8_HUMAN,tr|H0YFV6|H0YFV6_HUMAN,tr|B4DTN4|B4DTN4_HUMAN" 4 1207.6288 0.02 97378 9305 2 1207.626731 604.8217 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 6 1951.8 - 3.96E+06 - - - -1.7265 - 2.699 0.54 - 778.2 1 2 0 -0.0021 13 0 0 0 7.88E+06 4.50E+08 - - - 5.577 0.9999 221125_WJC_METTL3_EV_vs_WT_F07.09306.09306.3 0.000906 19/56 K.GSC[160.03]GIGGGIGGGSSR.L "sp|P02533|K1C14_HUMAN,sp|P08779|K1C16_HUMAN,tr|K7ENV3|K7ENV3_HUMAN" 3 1277.5782 999 97379 9306 3 1277.575555 426.8667 "Keratin, type I cytoskeletal 14 OS=Homo sapiens OX=9606 GN=KRT14 PE=1 SV=4" 8.25 1951.9 - 2.15E+06 - - - -2.1071 - 3.179 0.456 - 381.8 1 2 0 -0.0027 15 0 0 0 7.60E+07 0.00E+00 - - - 6.6411 0.9997 221125_WJC_METTL3_EV_vs_WT_F07.09307.09307.4 0.00184 18/84 R.FR[166.11]PAGAAPR[166.11]PPPK[136.11]PM.- "sp|Q5JNZ5|RS26L_HUMAN,sp|P62854|RS26_HUMAN" 2 1616.8968 1.03 97380 9307 4 1616.893841 405.2315 Putative 40S ribosomal protein S26-like 1 OS=Homo sapiens OX=9606 GN=RPS26P11 PE=5 SV=1 12.01 1952.1 - 1.76E+06 - - - -1.8158 - 1.963 0.37 - 161.8 1 2 0 -0.0029 15 0 0 0 7.00E+07 6.78E+07 - - - 2.687 1 221125_WJC_METTL3_EV_vs_WT_F07.09308.09308.3 2.05E-11 20/56 R.APQEFMTSHSEAGSR[166.11].L sp|Q9BRR6|ADPGK_HUMAN 1 1643.7237 1.05 97381 9308 3 1643.71887 548.9152 ADP-dependent glucokinase OS=Homo sapiens OX=9606 GN=ADPGK PE=1 SV=1 5.4 1952.2 - 1.34E+06 - - - -2.9622 - 3.638 0.592 - 735.3 1 2 0 -0.0049 15 0 0 0 6.35E+07 6.05E+07 - - - 8.5087 1 221125_WJC_METTL3_EV_vs_WT_F07.09309.09309.2 4.50E-09 14/20 L.PQTSDDEK[136.11]K[136.11]DF.- sp|Q9GZT3|SLIRP_HUMAN 1 1324.6118 1.99 97382 9309 2 1324.606668 663.3132 "SRA stem-loop-interacting RNA-binding protein, mitochondrial OS=Homo sapiens OX=9606 GN=SLIRP PE=1 SV=1" 4.23 1952.3 - 817826 - - - -3.8555 - 2.625 0.638 - 568.3 1 1 1 -0.0051 11 0 0 0 3.84E+07 1.93E+07 - - - 6.3624 1 221125_WJC_METTL3_EV_vs_WT_F07.09310.09310.2 2.91E-08 18/26 K.GLNTDELGQKEEAK.N sp|Q8N0X7|SPART_HUMAN 1 1530.7526 0.97 97383 9310 2 1530.75143 766.3836 Spartin OS=Homo sapiens OX=9606 GN=SPART PE=1 SV=1 4.41 1952.5 - 750336 - - - -0.7421 - 3.416 0.666 - 1285.9 1 2 1 -0.0011 14 0 0 0 1.13E+07 1.16E+07 - - - 7.0425 1 221125_WJC_METTL3_EV_vs_WT_F07.09316.09316.3 1.35E-06 18/52 R.SSSLGSTPHEELER[166.11].L "sp|Q9NRA8|4ET_HUMAN,tr|B1AKL4|B1AKL4_HUMAN" 2 1537.7248 3.24 97387 9316 3 1537.721426 513.5822 Eukaryotic translation initiation factor 4E transporter OS=Homo sapiens OX=9606 GN=EIF4ENIF1 PE=1 SV=2 4.75 1953.2 - 7.29E+06 - - - -2.1844 - 2.733 0.558 - 574 1 2 0 -0.0034 14 0 0 0 4.20E+08 1.30E+08 - - - 7.4321 0.9994 221125_WJC_METTL3_EV_vs_WT_F07.09317.09317.2 0.199 12-Aug R.FSGVPDR.F "sp|A0A075B6R9|KVD24_HUMAN,sp|A0A0C4DH68|KV224_HUMAN,sp|A2NJV5|KV229_HUMAN,sp|A0A075B6S2|KVD29_HUMAN,sp|A0A0A0MRZ7|KVD26_HUMAN" 5 776.3817 84.62 97388 9317 2 776.380926 389.1981 Probable non-functional immunoglobulin kappa variable 2D-24 OS=Homo sapiens OX=9606 GN=IGKV2D-24 PE=1 SV=1 5.84 1953.2 - 2.84E+06 - - - -1.0008 - 1.76 0.293 - 206.3 1 2 0 -0.0008 7 0 0 0 4.17E+08 4.93E+06 - - - 2.9961 1 221125_WJC_METTL3_EV_vs_WT_F07.09320.09320.2 6.26E-07 24-Dec K.EVASNSELVQSSR.S "sp|P08779|K1C16_HUMAN,tr|K7ENW6|K7ENW6_HUMAN" 2 1404.6845 999 97391 9320 2 1404.679598 703.3495 "Keratin, type I cytoskeletal 16 OS=Homo sapiens OX=9606 GN=KRT16 PE=1 SV=4" 4.53 1953.6 - 956764 - - - -3.4798 - 2.623 0.602 - 571.1 1 2 0 -0.0049 13 0 0 0 6.12E+07 0.00E+00 - - - 5.9608 0.9995 221125_WJC_METTL3_EV_vs_WT_F07.09321.09321.3 0.000282 Dec-36 R.TKYEHELALR.Q sp|P08779|K1C16_HUMAN 1 1258.667 16.42 97392 9321 3 1258.665019 420.5629 "Keratin, type I cytoskeletal 16 OS=Homo sapiens OX=9606 GN=KRT16 PE=1 SV=4" 6.42 1953.7 - 647063 - - - -1.5628 - 2.407 0.385 - 229.6 1 2 1 -0.002 10 0 0 0 1.20E+07 7.32E+05 - - - 5.3971 0.9875 221125_WJC_METTL3_EV_vs_WT_F07.09322.09322.3 0.0582 Sep-44 K.K[136.11]FAEALGSTEAK[136.11].A "sp|P78347|GTF2I_HUMAN,tr|A0A494C0Q7|A0A494C0Q7_HUMAN,tr|A0A494C1K3|A0A494C1K3_HUMAN" 3 1266.6791 0.77 97393 9322 3 1266.675544 423.2336 General transcription factor II-I OS=Homo sapiens OX=9606 GN=GTF2I PE=1 SV=2 6.14 1953.9 - 504006 - - - -2.7813 - 1.631 0.223 - 122.1 1 2 0 -0.0035 12 0 0 0 2.51E+07 3.26E+07 - - - 2.3812 1 221125_WJC_METTL3_EV_vs_WT_F07.09326.09326.2 2.68E-07 16/24 R.YESHPVC[160.03]ADLQAK.L "sp|Q9NX63|MIC19_HUMAN,tr|C9JRZ6|C9JRZ6_HUMAN" 2 1516.698 1.33 97395 9326 2 1516.702541 759.3563 MICOS complex subunit MIC19 OS=Homo sapiens OX=9606 GN=CHCHD3 PE=1 SV=1 5.32 1954.4 - 1.82E+06 - - - 2.9755 - 3.409 0.636 - 648.1 1 2 0 0.0045 13 0 0 0 3.09E+07 2.33E+07 - - - 6.8847 0.9854 221125_WJC_METTL3_EV_vs_WT_F07.09328.09328.3 0.00576 15/48 K.QIEELKGQEVSPK.V "sp|P09936|UCHL1_HUMAN,tr|D6R956|D6R956_HUMAN,tr|D6RE83|D6RE83_HUMAN,tr|D6R974|D6R974_HUMAN" 4 1483.7882 0.69 97397 9328 3 1483.783183 495.6034 Ubiquitin carboxyl-terminal hydrolase isozyme L1 OS=Homo sapiens OX=9606 GN=UCHL1 PE=1 SV=2 4.79 1954.6 - 1.11E+06 - - - -3.3967 - 2.07 0.28 - 273.9 1 2 1 -0.005 13 0 0 0 2.49E+07 3.59E+07 - - - 3.6329 0.9998 221125_WJC_METTL3_EV_vs_WT_F07.09329.09329.2 2.92E-05 26-Nov R.SSSLGSTPHEELER[166.11].L "sp|Q9NRA8|4ET_HUMAN,tr|B1AKL4|B1AKL4_HUMAN" 2 1537.7248 5.77 97398 9329 2 1537.722036 769.8697 Eukaryotic translation initiation factor 4E transporter OS=Homo sapiens OX=9606 GN=EIF4ENIF1 PE=1 SV=2 4.75 1954.7 - 849391 - - - -1.7877 - 2.206 0.569 - 340.1 1 2 0 -0.0027 14 0 0 0 5.66E+07 9.80E+06 - - - 5.2282 0.9999 221125_WJC_METTL3_EV_vs_WT_F07.09332.09332.3 0.000151 13/36 K.QQEELDALKK.T sp|O95347|SMC2_HUMAN 1 1200.635 0.84 97399 9332 3 1200.632609 401.2189 Structural maintenance of chromosomes protein 2 OS=Homo sapiens OX=9606 GN=SMC2 PE=1 SV=2 4.68 1955.1 - 831355 - - - -2.0056 - 2.139 0.479 - 242.2 1 2 0 -0.0024 10 0 0 0 2.52E+07 2.99E+07 - - - 6.1002 0.9999 221125_WJC_METTL3_EV_vs_WT_F07.09333.09333.2 5.92E-06 26-Dec R.SSSLGSTPHEELER.L "sp|Q9NRA8|4ET_HUMAN,tr|B1AKL4|B1AKL4_HUMAN" 2 1527.7165 9.62 97400 9333 2 1527.715423 764.8655 Eukaryotic translation initiation factor 4E transporter OS=Homo sapiens OX=9606 GN=EIF4ENIF1 PE=1 SV=2 4.75 1955.3 - 1.20E+06 - - - -0.7148 - 2.457 0.499 - 387.7 1 2 0 -0.0011 14 0 0 0 9.43E+07 9.80E+06 - - - 4.9821 0.9998 221125_WJC_METTL3_EV_vs_WT_F07.09334.09334.3 0.0114 Nov-52 R.SSSLGSTPHEELER.L "sp|Q9NRA8|4ET_HUMAN,tr|B1AKL4|B1AKL4_HUMAN" 2 1527.7165 4.65 97401 9334 3 1527.714537 510.2461 Eukaryotic translation initiation factor 4E transporter OS=Homo sapiens OX=9606 GN=EIF4ENIF1 PE=1 SV=2 4.75 1955.3 - 1.15E+07 - - - -1.2947 - 2.208 0.382 - 97.2 1 2 0 -0.002 14 0 0 0 6.03E+08 1.30E+08 - - - 4.9034 0.9999 221125_WJC_METTL3_EV_vs_WT_F07.09340.09340.3 0.00126 19/56 R.LIQSHPESAEDLQEK[136.11].C "sp|Q13813|SPTN1_HUMAN,tr|A0A0D9SF54|A0A0D9SF54_HUMAN,tr|A0A0D9SGF6|A0A0D9SGF6_HUMAN" 3 1730.8566 1.53 97405 9340 3 1730.855897 577.9595 "Spectrin alpha chain, non-erythrocytic 1 OS=Homo sapiens OX=9606 GN=SPTAN1 PE=1 SV=3" 4.4 1956.1 - 2.81E+06 - - - -0.4316 - 2.426 0.411 - 314.6 1 2 0 -0.0007 15 0 0 0 6.33E+07 4.14E+07 - - - 5.4346 0.9999 221125_WJC_METTL3_EV_vs_WT_F07.09341.09341.3 0.00104 17/60 K.AGVQSVGEKESLEAAK.E "sp|Q86VM9|ZCH18_HUMAN,tr|E7ERS3|E7ERS3_HUMAN" 2 1601.8261 3.7 97406 9341 3 1601.823779 534.9493 Zinc finger CCCH domain-containing protein 18 OS=Homo sapiens OX=9606 GN=ZC3H18 PE=1 SV=2 4.79 1956.2 - 1.19E+06 - - - -1.4271 - 3.368 0.492 - 405.9 1 2 1 -0.0023 16 0 0 0 2.31E+07 6.24E+06 - - - 7.1405 0.9997 221125_WJC_METTL3_EV_vs_WT_F07.09344.09344.3 0.000664 Dec-48 K.K[136.11]GGPSPGDVEAIK[136.11].N "sp|P09661|RU2A_HUMAN,tr|H0YMA0|H0YMA0_HUMAN,tr|H0YLR3|H0YLR3_HUMAN" 3 1269.69 1.26 97409 9344 3 1269.688263 424.2373 U2 small nuclear ribonucleoprotein A' OS=Homo sapiens OX=9606 GN=SNRPA1 PE=1 SV=2 6.07 1956.5 - 748834 - - - -1.3413 - 2.39 0.304 - 178 1 2 0 -0.0017 13 0 0 0 4.30E+07 3.42E+07 - - - 4.2912 0.9999 221125_WJC_METTL3_EV_vs_WT_F07.09347.09347.3 0.00524 16/48 R.LDDHALTGASDSR.V "sp|Q12788|TBL3_HUMAN,tr|J3KNP2|J3KNP2_HUMAN" 2 1356.627 1.67 97410 9347 3 1356.623898 453.2163 Transducin beta-like protein 3 OS=Homo sapiens OX=9606 GN=TBL3 PE=1 SV=2 4.41 1956.9 - 940132 - - - -2.2659 - 2.872 0.479 - 310.9 1 2 0 -0.0031 13 0 0 0 5.73E+07 3.43E+07 - - - 6.74 1 221125_WJC_METTL3_EV_vs_WT_F07.09348.09348.2 2.53E-10 17/24 K.GEFKDEEETVTTK.H sp|Q14677|EPN4_HUMAN 1 1511.6991 1.6 97411 9348 2 1511.696796 756.8568 Clathrin interactor 1 OS=Homo sapiens OX=9606 GN=CLINT1 PE=1 SV=1 4.25 1957 - 1.32E+06 - - - -1.5466 - 3.199 0.671 - 796.6 1 2 1 -0.0023 13 0 0 0 2.61E+08 1.63E+08 - - - 6.9807 0.9998 221125_WJC_METTL3_EV_vs_WT_F07.09350.09350.2 0.0083 22-Nov K.KFAEALGSTEAK.A "sp|P78347|GTF2I_HUMAN,tr|A0A494C0Q7|A0A494C0Q7_HUMAN,tr|A0A494C1K3|A0A494C1K3_HUMAN" 3 1250.6507 2.06 97413 9350 2 1250.650714 626.3326 General transcription factor II-I OS=Homo sapiens OX=9606 GN=GTF2I PE=1 SV=2 6.14 1957.3 - 358993 - - - 0.0376 - 2.202 0.425 - 354.2 1 2 0 0 12 0 0 0 3.81E+06 1.85E+06 - - - 4.257 0.9999 221125_WJC_METTL3_EV_vs_WT_F07.09355.09355.3 0.000654 Dec-44 K.SHFVAASLSNQK.A "sp|Q86XP3|DDX42_HUMAN,tr|A0A0A0MSJ0|A0A0A0MSJ0_HUMAN" 2 1287.6571 0.59 97416 9355 3 1287.657513 430.2263 ATP-dependent RNA helicase DDX42 OS=Homo sapiens OX=9606 GN=DDX42 PE=1 SV=1 8.49 1957.9 - 1.31E+06 - - - 0.2827 - 2.471 0.405 - 300.7 1 2 0 0.0004 12 0 0 0 4.31E+07 7.31E+07 - - - 5.5627 0.9933 221125_WJC_METTL3_EV_vs_WT_F07.09356.09356.2 0.000111 18-Aug K.QQEELDALK[136.11]K[136.11].T sp|O95347|SMC2_HUMAN 1 1216.6634 0.65 97417 9356 2 1216.656705 609.339 Structural maintenance of chromosomes protein 2 OS=Homo sapiens OX=9606 GN=SMC2 PE=1 SV=2 4.68 1958 - 383751 - - - -5.5167 - 1.515 0.492 - 193.2 1 2 0 -0.0067 10 0 0 0 2.82E+06 4.31E+06 - - - 3.8324 0.9998 221125_WJC_METTL3_EV_vs_WT_F07.09357.09357.2 8.97E-07 15/22 K.SHFVAASLSNQK.A "sp|Q86XP3|DDX42_HUMAN,tr|A0A0A0MSJ0|A0A0A0MSJ0_HUMAN" 2 1287.6571 1.15 97418 9357 2 1287.654657 644.8359 ATP-dependent RNA helicase DDX42 OS=Homo sapiens OX=9606 GN=DDX42 PE=1 SV=1 8.49 1958.2 - 342131 - - - -1.9353 - 2.69 0.498 - 692 1 2 0 -0.0025 12 0 0 0 1.49E+07 1.29E+07 - - - 5.3221 1 221125_WJC_METTL3_EV_vs_WT_F07.09360.09360.3 2.81E-08 14/56 R.LIQSHPESAEDLQEK.C "sp|Q13813|SPTN1_HUMAN,tr|A0A0D9SF54|A0A0D9SF54_HUMAN,tr|A0A0D9SGF6|A0A0D9SGF6_HUMAN" 3 1722.8424 1.51 97420 9360 3 1722.840569 575.2881 "Spectrin alpha chain, non-erythrocytic 1 OS=Homo sapiens OX=9606 GN=SPTAN1 PE=1 SV=3" 4.4 1958.5 - 3.33E+06 - - - -1.0883 - 2.8 0.561 - 188.7 1 2 0 -0.0019 15 0 0 0 6.26E+07 4.14E+07 - - - 7.4807 0.9273 221125_WJC_METTL3_EV_vs_WT_F07.09361.09361.3 0.00809 13/40 V.TAIHIDPATHR[166.11].Q "sp|P49327|FAS_HUMAN,tr|A0A0U1RQF0|A0A0U1RQF0_HUMAN" 2 1240.6552 0.03 97421 9361 3 1240.654018 414.559 Fatty acid synthase OS=Homo sapiens OX=9606 GN=FASN PE=1 SV=3 6.61 1958.6 - 311378 - - - -0.9439 - 2.535 0.21 - 208.7 1 1 0 -0.0012 11 0 0 0 9.56E+06 2.73E+08 - - - 3.5235 1 221125_WJC_METTL3_EV_vs_WT_F07.09366.09366.3 9.01E-09 16/48 K.GEFKDEEETVTTK.H sp|Q14677|EPN4_HUMAN 1 1511.6991 1.1 97424 9366 3 1511.697468 504.907 Clathrin interactor 1 OS=Homo sapiens OX=9606 GN=CLINT1 PE=1 SV=1 4.25 1959.3 - 1.85E+07 - - - -1.1021 - 3.106 0.642 - 330.5 1 2 1 -0.0017 13 0 0 0 7.89E+08 7.15E+08 - - - 8.77 0.9995 221125_WJC_METTL3_EV_vs_WT_F07.09368.09368.3 0.00209 Dec-44 K.ETAENYLGHTAK[136.11].N "sp|P38646|GRP75_HUMAN,tr|H0Y8K0|H0Y8K0_HUMAN,tr|A0A7I2V2S7|A0A7I2V2S7_HUMAN,tr|A0A7I2V2G2|A0A7I2V2G2_HUMAN,tr|A0A7I2V3F7|A0A7I2V3F7_HUMAN,tr|A0A7I2YQB2|A0A7I2YQB2_HUMAN,tr|D6RCD7|D6RCD7_HUMAN" 7 1340.6452 0.5 97426 9368 3 1340.642834 447.889 "Stress-70 protein, mitochondrial OS=Homo sapiens OX=9606 GN=HSPA9 PE=1 SV=2" 5.4 1959.4 - 3.19E+06 - - - -1.7603 - 1.829 0.36 - 194.6 1 2 0 -0.0024 12 0 0 0 3.50E+08 7.02E+08 - - - 4.2265 0.9997 221125_WJC_METTL3_EV_vs_WT_F07.09370.09370.2 5.12E-05 24-Nov K.SSSQIPAQPSVAK[136.11].V "sp|Q9Y520|PRC2C_HUMAN,tr|A0A0A0MS30|A0A0A0MS30_HUMAN,tr|E7EPN9|E7EPN9_HUMAN" 3 1306.6972 1.2 97428 9370 2 1306.696687 654.3559 Protein PRRC2C OS=Homo sapiens OX=9606 GN=PRRC2C PE=1 SV=4 8.47 1959.6 - 1.02E+06 - - - -0.4156 - 1.725 0.42 - 287.6 1 2 0 -0.0005 13 0 0 0 1.48E+08 1.23E+08 - - - 3.5423 0.9998 221125_WJC_METTL3_EV_vs_WT_F07.09371.09371.3 0.000914 17/52 K.QGIETPEDQNDLR[166.11]K[136.11].M "sp|Q15637|SF01_HUMAN,tr|A0A7P0T9U7|A0A7P0T9U7_HUMAN" 2 1659.8183 1.24 97429 9371 3 1659.818828 554.28 Splicing factor 1 OS=Homo sapiens OX=9606 GN=SF1 PE=1 SV=4 4.32 1959.7 - 867711 - - - 0.3193 - 2.826 0.307 - 348.1 1 2 0 0.0005 14 0 0 0 7.06E+07 5.68E+07 - - - 4.7234 0.9995 221125_WJC_METTL3_EV_vs_WT_F07.09375.09375.2 1.08E-08 22-Dec K.SNVSDAVAQSTR[166.11].L sp|P60174|TPIS_HUMAN 1 1243.6032 1.36 97433 9375 2 1243.599462 622.8089 Triosephosphate isomerase OS=Homo sapiens OX=9606 GN=TPI1 PE=1 SV=4 5.55 1960.2 - 315194 - - - -3.0162 - 2.447 0.488 - 497.1 1 2 0 -0.0038 12 0 0 0 5.96E+07 4.38E+07 - - - 4.9987 0.9999 221125_WJC_METTL3_EV_vs_WT_F07.09378.09378.3 1.99E-05 13/48 R.LDDHALTGASDSR[166.11].V "sp|Q12788|TBL3_HUMAN,tr|J3KNP2|J3KNP2_HUMAN" 2 1366.6352 1.68 97434 9378 3 1366.631183 456.5524 Transducin beta-like protein 3 OS=Homo sapiens OX=9606 GN=TBL3 PE=1 SV=2 4.41 1960.6 - 3.38E+06 - - - -2.9701 - 2.754 0.51 - 213.6 1 2 0 -0.0041 13 0 0 0 5.78E+07 3.44E+07 - - - 6.9716 1 221125_WJC_METTL3_EV_vs_WT_F07.09379.09379.3 0.000319 16/52 K.QGIETPEDQNDLRK.M "sp|Q15637|SF01_HUMAN,tr|A0A7P0T9U7|A0A7P0T9U7_HUMAN" 2 1641.7958 1.24 97435 9379 3 1641.794781 548.2726 Splicing factor 1 OS=Homo sapiens OX=9606 GN=SF1 PE=1 SV=4 4.32 1960.7 - 1.51E+06 - - - -0.6377 - 2.749 0.453 - 418.8 1 2 0 -0.001 14 0 0 0 7.06E+07 5.68E+07 - - - 6.2776 1 221125_WJC_METTL3_EV_vs_WT_F07.09380.09380.3 1.53E-05 13/40 K.TQPTVINNLK[136.11]K[136.11].G sp|O15226|NKRF_HUMAN 1 1270.758 1.05 97436 9380 3 1270.756814 424.5933 NF-kappa-B-repressing factor OS=Homo sapiens OX=9606 GN=NKRF PE=1 SV=2 10 1960.8 - 1.09E+06 - - - -0.9223 - 2.471 0.432 - 255.4 1 2 0 -0.0012 11 0 0 0 4.35E+07 4.14E+07 - - - 5.9259 1 221125_WJC_METTL3_EV_vs_WT_F07.09383.09383.2 0.000641 14/22 K.SNVSDAVAQSTR.L sp|P60174|TPIS_HUMAN 1 1233.5949 1.36 97439 9383 2 1233.59713 617.8047 Triosephosphate isomerase OS=Homo sapiens OX=9606 GN=TPI1 PE=1 SV=4 5.55 1961 - 817678 - - - 1.7729 - 2.685 0.592 - 633 1 2 0 0.0022 12 0 0 0 5.96E+07 4.38E+07 - - - 6.0116 0.9999 221125_WJC_METTL3_EV_vs_WT_F07.09385.09385.2 6.08E-07 22-Dec K.SNVSDAVAQSTR[166.11].L sp|P60174|TPIS_HUMAN 1 1243.6032 1.36 97441 9385 2 1243.603164 622.8089 Triosephosphate isomerase OS=Homo sapiens OX=9606 GN=TPI1 PE=1 SV=4 5.55 1961.3 - 594086 - - - -0.0394 - 2.467 0.497 - 493.8 1 2 0 0 12 0 0 0 5.96E+07 4.38E+07 - - - 5.0878 0.9987 221125_WJC_METTL3_EV_vs_WT_F07.09386.09386.2 8.72E-05 24-Dec R.LDDHALTGASDSR[166.11].V "sp|Q12788|TBL3_HUMAN,tr|J3KNP2|J3KNP2_HUMAN" 2 1366.6352 1.47 97442 9386 2 1366.629476 684.3249 Transducin beta-like protein 3 OS=Homo sapiens OX=9606 GN=TBL3 PE=1 SV=2 4.41 1961.4 - 547450 - - - -4.2191 - 2.269 0.509 - 468.8 1 2 0 -0.0058 13 0 0 0 6.99E+06 4.75E+06 - - - 4.9015 1 221125_WJC_METTL3_EV_vs_WT_F07.09387.09387.2 4.95E-08 14/24 R.EVATNSELVQSGK.S "sp|Q04695|K1C17_HUMAN,sp|P02533|K1C14_HUMAN,tr|K7ESE1|K7ESE1_HUMAN,tr|F5GWP8|F5GWP8_HUMAN" 4 1360.6834 999 97443 9387 2 1360.685423 681.349 "Keratin, type I cytoskeletal 17 OS=Homo sapiens OX=9606 GN=KRT17 PE=1 SV=2" 4.53 1961.6 - 505763 - - - 1.4691 - 2.838 0.607 - 694.2 1 2 0 0.002 13 0 0 0 6.16E+07 0.00E+00 - - - 6.2008 0.9994 221125_WJC_METTL3_EV_vs_WT_F07.09388.09388.2 0.000863 18-Oct K.AEAESLYQSK.Y sp|P04264|K2C1_HUMAN 1 1124.535 140.43 97444 9388 2 1124.537411 563.2748 "Keratin, type II cytoskeletal 1 OS=Homo sapiens OX=9606 GN=KRT1 PE=1 SV=6" 4.53 1961.7 - 329935 - - - 2.1716 - 2.061 0.373 - 381 1 2 0 0.0024 10 0 0 0 1.39E+07 9.91E+04 - - - 3.8139 0.9999 221125_WJC_METTL3_EV_vs_WT_F07.09391.09391.3 0.019 13/48 K.KGGPSPGDVEAIK.N "sp|P09661|RU2A_HUMAN,tr|H0YMA0|H0YMA0_HUMAN,tr|H0YLR3|H0YLR3_HUMAN" 3 1253.6616 1.24 97446 9391 3 1253.66061 418.8945 U2 small nuclear ribonucleoprotein A' OS=Homo sapiens OX=9606 GN=SNRPA1 PE=1 SV=2 6.07 1962 - 1.28E+06 - - - -0.7626 - 2.399 0.375 - 234.6 1 2 0 -0.001 13 0 0 0 4.33E+07 3.49E+07 - - - 5.0931 0.9988 221125_WJC_METTL3_EV_vs_WT_F07.09393.09393.3 0.0753 Nov-44 K.ETAENYLGHTAK.N "sp|P38646|GRP75_HUMAN,tr|H0Y8K0|H0Y8K0_HUMAN,tr|A0A7I2V2S7|A0A7I2V2S7_HUMAN,tr|A0A7I2V2G2|A0A7I2V2G2_HUMAN,tr|A0A7I2V3F7|A0A7I2V3F7_HUMAN,tr|A0A7I2YQB2|A0A7I2YQB2_HUMAN,tr|D6RCD7|D6RCD7_HUMAN" 7 1332.631 0.46 97447 9393 3 1332.630473 445.2176 "Stress-70 protein, mitochondrial OS=Homo sapiens OX=9606 GN=HSPA9 PE=1 SV=2" 5.4 1962.2 - 9.69E+06 - - - -0.391 - 1.785 0.271 - 167.2 1 2 0 -0.0005 12 0 0 0 3.24E+08 6.97E+08 - - - 3.1673 0.9998 221125_WJC_METTL3_EV_vs_WT_F07.09394.09394.3 0.000906 Nov-44 K.SHFVAASLSNQK[136.11].A "sp|Q86XP3|DDX42_HUMAN,tr|A0A0A0MSJ0|A0A0A0MSJ0_HUMAN" 2 1295.6713 0.5 97448 9394 3 1295.670159 432.8977 ATP-dependent RNA helicase DDX42 OS=Homo sapiens OX=9606 GN=DDX42 PE=1 SV=1 8.49 1962.3 - 4.15E+06 - - - -0.9184 - 1.909 0.374 - 174 1 2 0 -0.0012 12 0 0 0 4.40E+07 8.81E+07 - - - 4.5016 0.9999 221125_WJC_METTL3_EV_vs_WT_F07.09395.09395.2 0.000472 22-Sep K.ETAENYLGHTAK[136.11].N "sp|P38646|GRP75_HUMAN,tr|H0Y8K0|H0Y8K0_HUMAN,tr|A0A7I2V2S7|A0A7I2V2S7_HUMAN,tr|A0A7I2V2G2|A0A7I2V2G2_HUMAN,tr|A0A7I2V3F7|A0A7I2V3F7_HUMAN,tr|A0A7I2YQB2|A0A7I2YQB2_HUMAN,tr|D6RCD7|D6RCD7_HUMAN" 7 1340.6452 0.46 97449 9395 2 1340.644237 671.3299 "Stress-70 protein, mitochondrial OS=Homo sapiens OX=9606 GN=HSPA9 PE=1 SV=2" 5.4 1962.4 - 2.94E+06 - - - -0.7138 - 2.136 0.499 - 304.3 1 2 0 -0.001 12 0 0 0 5.30E+07 1.14E+08 - - - 4.7232 0.9998 221125_WJC_METTL3_EV_vs_WT_F07.09396.09396.3 0.00127 Oct-40 K.TQPTVINNLKK.G sp|O15226|NKRF_HUMAN 1 1254.7296 1.05 97450 9396 3 1254.72922 419.2505 NF-kappa-B-repressing factor OS=Homo sapiens OX=9606 GN=NKRF PE=1 SV=2 10 1962.4 - 1.98E+06 - - - -0.2917 - 1.936 0.369 - 139.3 1 2 0 -0.0004 11 0 0 0 4.32E+07 4.12E+07 - - - 4.5306 0.9835 221125_WJC_METTL3_EV_vs_WT_F07.09397.09397.3 0.062 Dec-36 R.LQAELDHLRK.C "sp|Q14687|GSE1_HUMAN,tr|H0Y613|H0Y613_HUMAN" 2 1221.683 2.8 97451 9397 3 1221.682277 408.2349 Genetic suppressor element 1 OS=Homo sapiens OX=9606 GN=GSE1 PE=1 SV=3 6.75 1962.5 - 1.09E+06 - - - -0.5673 - 2.272 0.051 - 164 1 2 0 -0.0007 10 0 0 0 1.68E+07 6.01E+06 - - - 1.5051 0.9952 221125_WJC_METTL3_EV_vs_WT_F07.09399.09399.3 0.459 Oct-40 K.YFHPPAHLQAK.L "sp|Q9NR56|MBNL1_HUMAN,sp|Q5VZF2|MBNL2_HUMAN,tr|H7C4T5|H7C4T5_HUMAN,tr|Q86VM6|Q86VM6_HUMAN,tr|H7C4Y1|H7C4Y1_HUMAN,tr|A0A0A0MQX8|A0A0A0MQX8_HUMAN,tr|A0A7P0T9I3|A0A7P0T9I3_HUMAN,tr|C9JCX1|C9JCX1_HUMAN,tr|C9JP00|C9JP00_HUMAN,tr|O95205|O95205_HUMAN" 10 1307.6775 0.51 97453 9399 3 1307.678986 436.8998 Muscleblind-like protein 1 OS=Homo sapiens OX=9606 GN=MBNL1 PE=1 SV=2 8.61 1962.7 - 953178 - - - 1.1432 - 1.898 0.18 - 119.4 1 2 0 0.0015 11 0 0 0 1.33E+07 2.62E+07 - - - 2.3668 1 221125_WJC_METTL3_EV_vs_WT_F07.09400.09400.2 7.20E-07 15/20 E.FKDEEETVTTK.H sp|Q14677|EPN4_HUMAN 1 1325.6351 999 97454 9400 2 1325.635872 663.8248 Clathrin interactor 1 OS=Homo sapiens OX=9606 GN=CLINT1 PE=1 SV=1 4.41 1962.8 - 542152 - - - 0.5997 - 2.622 0.615 - 481.8 1 1 1 0.0008 11 0 0 0 9.50E+06 0.00E+00 - - - 6.1908 0.9976 221125_WJC_METTL3_EV_vs_WT_F07.09401.09401.2 0.000439 14/26 K.TGQAPGYSYTAANK.N "sp|P99999|CYC_HUMAN,tr|C9JFR7|C9JFR7_HUMAN" 2 1427.6681 0.07 97455 9401 2 1427.661162 714.8413 Cytochrome c OS=Homo sapiens OX=9606 GN=CYCS PE=1 SV=2 8.17 1962.9 - 376816 - - - -4.8653 - 2.442 0.456 - 560.7 1 2 0 -0.0069 14 0 0 0 8.92E+06 1.35E+08 - - - 4.6473 1 221125_WJC_METTL3_EV_vs_WT_F07.09402.09402.2 1.10E-07 13/20 K.HADYIASYGSK[136.11].K "sp|P53611|PGTB2_HUMAN,tr|Q5T4U8|Q5T4U8_HUMAN" 2 1218.5761 0.9 97456 9402 2 1218.571973 610.2953 Geranylgeranyl transferase type-2 subunit beta OS=Homo sapiens OX=9606 GN=RABGGTB PE=1 SV=2 6.74 1963.1 - 366806 - - - -3.3473 - 2.803 0.634 - 443.5 1 2 0 -0.0041 11 0 0 0 9.29E+06 1.03E+07 - - - 6.5107 0.9998 221125_WJC_METTL3_EV_vs_WT_F07.09408.09408.3 0.0198 Oct-40 R.K[136.11]DDPTLLSSGR[166.11].V "sp|P22061|PIMT_HUMAN,tr|F6S8N6|F6S8N6_HUMAN,tr|A0A3F2YNX8|A0A3F2YNX8_HUMAN,tr|A0A0A0MRJ6|A0A0A0MRJ6_HUMAN" 4 1205.6371 0.81 97460 9408 3 1205.635433 402.8863 Protein-L-isoaspartate(D-aspartate) O-methyltransferase OS=Homo sapiens OX=9606 GN=PCMT1 PE=1 SV=4 5.96 1963.8 - 841982 - - - -1.3711 - 2.273 0.357 - 140.8 1 2 0 -0.0017 11 0 0 0 3.33E+07 4.14E+07 - - - 4.8523 0.9998 221125_WJC_METTL3_EV_vs_WT_F07.09410.09410.2 0.00283 20-Oct R.K[136.11]DDPTLLSSGR[166.11].V "sp|P22061|PIMT_HUMAN,tr|F6S8N6|F6S8N6_HUMAN,tr|A0A3F2YNX8|A0A3F2YNX8_HUMAN,tr|A0A0A0MRJ6|A0A0A0MRJ6_HUMAN" 4 1205.6371 0.89 97462 9410 2 1205.637981 603.8258 Protein-L-isoaspartate(D-aspartate) O-methyltransferase OS=Homo sapiens OX=9606 GN=PCMT1 PE=1 SV=4 5.96 1964 - 327996 - - - 0.7423 - 2.258 0.455 - 334 1 2 0 0.0009 11 0 0 0 1.73E+07 1.95E+07 - - - 4.6047 0.9997 221125_WJC_METTL3_EV_vs_WT_F07.09411.09411.2 0.078 24-Oct K.KGGPSPGDVEAIK.N "sp|P09661|RU2A_HUMAN,tr|H0YMA0|H0YMA0_HUMAN,tr|H0YLR3|H0YLR3_HUMAN" 3 1253.6616 1.31 97463 9411 2 1253.661508 627.8381 U2 small nuclear ribonucleoprotein A' OS=Homo sapiens OX=9606 GN=SNRPA1 PE=1 SV=2 6.07 1964.2 - 324823 - - - -0.0463 - 2.233 0.317 - 235.7 1 2 0 -0.0001 13 0 0 0 7.22E+06 5.51E+06 - - - 3.4442 0.9323 221125_WJC_METTL3_EV_vs_WT_F07.09412.09412.2 0.105 24-Mar R.ENQVSIEC[160.03]DTTC[160.03]K[136.11].E sp|Q6ZNB6|NFXL1_HUMAN 1 1590.6745 0.27 97464 9412 2 1590.669716 796.3445 NF-X1-type zinc finger protein NFXL1 OS=Homo sapiens OX=9606 GN=NFXL1 PE=1 SV=2 4.14 1964.3 - 305671 - - - -3.022 - 0.942 0.23 - 13 4 2 0 -0.0048 13 0 0 0 1.18E+06 4.29E+06 - - - 0.316 0.9893 221125_WJC_METTL3_EV_vs_WT_F07.09413.09413.3 2.20E-07 Oct-52 A.AGYPGQQQNFHSVR[166.11].E sp|Q12948|FOXC1_HUMAN 1 1597.7625 2.34 97465 9413 3 1597.765594 533.5948 Forkhead box protein C1 OS=Homo sapiens OX=9606 GN=FOXC1 PE=1 SV=3 8.8 1964.4 - 249794 - - - 1.9315 - 1.964 0.49 - 82.5 1 1 0 0.0031 14 0 0 0 6.02E+06 2.57E+06 - - - 5.7959 0.9998 221125_WJC_METTL3_EV_vs_WT_F07.09414.09414.2 0.0841 24-Nov K.K[136.11]GGPSPGDVEAIK[136.11].N "sp|P09661|RU2A_HUMAN,tr|H0YMA0|H0YMA0_HUMAN,tr|H0YLR3|H0YLR3_HUMAN" 3 1269.69 1.31 97466 9414 2 1269.688438 635.8523 U2 small nuclear ribonucleoprotein A' OS=Homo sapiens OX=9606 GN=SNRPA1 PE=1 SV=2 6.07 1964.6 - 214900 - - - -1.2034 - 2.29 0.46 - 362.5 1 2 0 -0.0015 13 0 0 0 7.22E+06 5.51E+06 - - - 4.5646 0.9998 221125_WJC_METTL3_EV_vs_WT_F07.09419.09419.3 1.15E-05 17/52 K.QLVSDEDK[136.11]AQLASK[136.11].L "sp|P09001|RM03_HUMAN,tr|E7ETU7|E7ETU7_HUMAN,tr|H0Y9G6|H0Y9G6_HUMAN,tr|E9PF06|E9PF06_HUMAN" 4 1546.8174 1.17 97469 9419 3 1546.817301 516.6131 "39S ribosomal protein L3, mitochondrial OS=Homo sapiens OX=9606 GN=MRPL3 PE=1 SV=1" 4.56 1965.2 - 1.91E+06 - - - -0.033 - 3.068 0.433 - 476.7 1 2 1 -0.0001 14 0 0 0 4.34E+07 3.72E+07 - - - 6.3467 0.9922 221125_WJC_METTL3_EV_vs_WT_F07.09421.09421.2 1.77E-06 18-Oct T.AENYLGHTAK[136.11].N "sp|P38646|GRP75_HUMAN,tr|H0Y8K0|H0Y8K0_HUMAN,tr|A0A7I2V2S7|A0A7I2V2S7_HUMAN,tr|A0A7I2V2G2|A0A7I2V2G2_HUMAN,tr|A0A7I2V3F7|A0A7I2V3F7_HUMAN,tr|A0A7I2YQB2|A0A7I2YQB2_HUMAN,tr|D6RCD7|D6RCD7_HUMAN" 7 1110.5549 2.68 97471 9421 2 1110.554228 556.2847 "Stress-70 protein, mitochondrial OS=Homo sapiens OX=9606 GN=HSPA9 PE=1 SV=2" 6.79 1965.4 - 983339 - - - -0.6258 - 1.967 0.526 - 441.2 1 1 0 -0.0007 10 0 0 0 4.44E+07 1.66E+07 - - - 4.8142 0.9999 221125_WJC_METTL3_EV_vs_WT_F07.09424.09424.3 2.19E-05 14/68 R.AADGGERPLAASPPGTVK.A "sp|O95785|WIZ_HUMAN,tr|A0A669KBG4|A0A669KBG4_HUMAN,tr|A0A2R8YFV2|A0A2R8YFV2_HUMAN,tr|A0A669KAV7|A0A669KAV7_HUMAN,tr|M0QXA7|M0QXA7_HUMAN,tr|A0A669KBH9|A0A669KBH9_HUMAN,tr|B9EGQ5|B9EGQ5_HUMAN" 7 1692.8795 1.6 97474 9424 3 1692.881808 565.3004 Protein Wiz OS=Homo sapiens OX=9606 GN=WIZ PE=1 SV=2 6.11 1965.8 - 452110 - - - 1.3645 - 2.544 0.449 - 253.8 1 2 0 0.0023 18 0 0 0 1.16E+08 7.28E+07 - - - 5.8704 0.9998 221125_WJC_METTL3_EV_vs_WT_F07.09425.09425.2 0.00631 20-Oct R.KDDPTLLSSGR.V "sp|P22061|PIMT_HUMAN,tr|F6S8N6|F6S8N6_HUMAN,tr|A0A3F2YNX8|A0A3F2YNX8_HUMAN,tr|A0A0A0MRJ6|A0A0A0MRJ6_HUMAN" 4 1187.6146 0.89 97475 9425 2 1187.614744 594.8146 Protein-L-isoaspartate(D-aspartate) O-methyltransferase OS=Homo sapiens OX=9606 GN=PCMT1 PE=1 SV=4 5.96 1965.9 - 342052 - - - 0.1078 - 2.136 0.382 - 312.1 1 2 0 0.0001 11 0 0 0 1.73E+07 1.95E+07 - - - 3.9155 0.9999 221125_WJC_METTL3_EV_vs_WT_F07.09428.09428.2 6.11E-06 24-Dec K.SSSQIPAQPSVAK.V "sp|Q9Y520|PRC2C_HUMAN,tr|A0A0A0MS30|A0A0A0MS30_HUMAN,tr|E7EPN9|E7EPN9_HUMAN" 3 1298.683 1.2 97477 9428 2 1298.683379 650.3488 Protein PRRC2C OS=Homo sapiens OX=9606 GN=PRRC2C PE=1 SV=4 8.47 1966.3 - 4.60E+06 - - - 0.2687 - 2.031 0.531 - 349.2 1 2 0 0.0003 13 0 0 0 1.48E+08 1.23E+08 - - - 4.7813 0.9985 221125_WJC_METTL3_EV_vs_WT_F07.09431.09431.3 0.0043 Dec-68 R.AADGGER[166.11]PLAASPPGTVK[136.11].A "sp|O95785|WIZ_HUMAN,tr|A0A669KBG4|A0A669KBG4_HUMAN,tr|A0A2R8YFV2|A0A2R8YFV2_HUMAN,tr|A0A669KAV7|A0A669KAV7_HUMAN,tr|M0QXA7|M0QXA7_HUMAN,tr|A0A669KBH9|A0A669KBH9_HUMAN,tr|B9EGQ5|B9EGQ5_HUMAN" 7 1710.902 1.6 97479 9431 3 1710.901129 571.3079 Protein Wiz OS=Homo sapiens OX=9606 GN=WIZ PE=1 SV=2 6.11 1966.7 - 453559 - - - -0.4904 - 1.87 0.264 - 110.2 1 2 0 -0.0008 18 0 0 0 1.16E+08 7.28E+07 - - - 3.0418 0.9988 221125_WJC_METTL3_EV_vs_WT_F07.09436.09436.2 3.60E-05 13/26 K.QLVSDEDK[136.11]AQLASK[136.11].L "sp|P09001|RM03_HUMAN,tr|E7ETU7|E7ETU7_HUMAN,tr|H0Y9G6|H0Y9G6_HUMAN,tr|E9PF06|E9PF06_HUMAN" 4 1546.8174 0.28 97484 9436 2 1546.818607 774.416 "39S ribosomal protein L3, mitochondrial OS=Homo sapiens OX=9606 GN=MRPL3 PE=1 SV=1" 4.56 1967.2 - 210009 - - - 0.8113 - 2.542 0.549 - 627.2 1 2 1 0.0013 14 0 0 0 5.54E+05 1.97E+06 - - - 5.4367 1 221125_WJC_METTL3_EV_vs_WT_F07.09442.09442.3 1.84E-05 17/52 R.C[160.03]QLQQAAALNAQHK.Q sp|Q96DF8|ESS2_HUMAN 1 1579.7889 0.92 97487 9442 3 1579.790112 527.6036 Splicing factor ESS-2 homolog OS=Homo sapiens OX=9606 GN=ESS2 PE=1 SV=1 8.23 1968 - 2.94E+06 - - - 0.7615 - 3.501 0.566 - 649.8 1 2 0 0.0012 14 0 0 0 4.19E+07 4.54E+07 - - - 8.18 1 221125_WJC_METTL3_EV_vs_WT_F07.09451.09451.3 1.76E-06 16/76 R.AAAAAATAPPSPGPAQPGPR.A sp|Q6SPF0|SAMD1_HUMAN 1 1754.9064 2.43 97494 9451 3 1754.910849 585.9761 Sterile alpha motif domain-containing protein 1 OS=Homo sapiens OX=9606 GN=SAMD1 PE=1 SV=1 9.79 1969 - 188515 - - - 2.546 - 3.089 0.554 - 345.6 1 2 0 0.0045 20 0 0 0 4.67E+07 1.92E+07 - - - 7.4515 1 221125_WJC_METTL3_EV_vs_WT_F07.09468.09468.2 1.19E-08 Oct-34 R.LALSQNQQSSGAAGPTGK.N "sp|O95232|LC7L3_HUMAN,tr|J3KPP4|J3KPP4_HUMAN,tr|D6RDI2|D6RDI2_HUMAN" 3 1713.8646 1.67 97510 9468 2 1713.863629 857.9396 Luc7-like protein 3 OS=Homo sapiens OX=9606 GN=LUC7L3 PE=1 SV=2 8.75 1970.6 - 139674 - - - -0.5526 - 2.514 0.606 - 277.6 1 2 0 -0.0009 18 0 0 0 2.81E+06 1.68E+06 - - - 5.7831 0.9914 221125_WJC_METTL3_EV_vs_WT_F07.09469.09469.2 0.189 24-May K.K[136.11]NSVVEASEAAYK[136.11].E "sp|Q04917|1433F_HUMAN,tr|A2IDB2|A2IDB2_HUMAN" 2 1410.7326 -1 97511 9469 2 1410.733234 706.3736 14-3-3 protein eta OS=Homo sapiens OX=9606 GN=YWHAH PE=1 SV=4 6.14 1970.7 - 123200 - - - 0.4785 - 1.166 0.182 - 66.6 1 2 0 0.0007 13 0 0 0 0.00E+00 0.00E+00 - - - 0.7792 0.9999 221125_WJC_METTL3_EV_vs_WT_F07.09472.09472.3 0.000435 Dec-40 R.KDDPTLLSSGR.V "sp|P22061|PIMT_HUMAN,tr|F6S8N6|F6S8N6_HUMAN,tr|A0A3F2YNX8|A0A3F2YNX8_HUMAN,tr|A0A0A0MRJ6|A0A0A0MRJ6_HUMAN" 4 1187.6146 0.8 97512 9472 3 1187.614934 396.8788 Protein-L-isoaspartate(D-aspartate) O-methyltransferase OS=Homo sapiens OX=9606 GN=PCMT1 PE=1 SV=4 5.96 1971.2 - 1.41E+06 - - - 0.2678 - 2.388 0.432 - 188.4 1 2 0 0.0003 11 0 0 0 3.32E+07 4.13E+07 - - - 5.8291 0.9999 221125_WJC_METTL3_EV_vs_WT_F07.09475.09475.2 1.11E-05 13/26 R.GNLGAGNGNLQGPR.H "sp|P43243|MATR3_HUMAN,tr|D6RE02|D6RE02_HUMAN,tr|B3KM87|B3KM87_HUMAN,tr|A8MXP9|A8MXP9_HUMAN,tr|D6RAY2|D6RAY2_HUMAN,tr|D6R991|D6R991_HUMAN,tr|A0A0R4J2E8|A0A0R4J2E8_HUMAN,tr|D6RAM9|D6RAM9_HUMAN,tr|D6RIA2|D6RIA2_HUMAN,tr|H0Y8T4|H0Y8T4_HUMAN,tr|D6REM6|D6REM6_HUMAN,tr|D6RBI2|D6RBI2_HUMAN" 12 1323.6644 1.41 97515 9475 2 1323.664962 662.8395 Matrin-3 OS=Homo sapiens OX=9606 GN=MATR3 PE=1 SV=2 9.75 1971.4 - 405778 - - - 0.4548 - 2.581 0.571 - 573.4 1 2 0 0.0006 14 0 0 0 1.54E+08 1.09E+08 - - - 5.6376 0.9999 221125_WJC_METTL3_EV_vs_WT_F07.09479.09479.2 0.000241 13/38 R.AAAAAATAPPSPGPAQPGPR.A sp|Q6SPF0|SAMD1_HUMAN 1 1754.9064 4 97519 9479 2 1754.908996 878.4605 Sterile alpha motif domain-containing protein 1 OS=Homo sapiens OX=9606 GN=SAMD1 PE=1 SV=1 9.79 1971.9 - 105579 - - - 1.4901 - 2.529 0.576 - 262.2 1 2 0 0.0026 20 0 0 0 1.68E+07 4.21E+06 - - - 5.5756 0.9939 221125_WJC_METTL3_EV_vs_WT_F07.09481.09481.3 0.000181 Oct-44 R.SKDEAEALYQTK.Y sp|Q7Z794|K2C1B_HUMAN 1 1381.6725 23.13 97520 9481 3 1381.675812 461.5648 "Keratin, type II cytoskeletal 1b OS=Homo sapiens OX=9606 GN=KRT77 PE=1 SV=3" 4.68 1972.2 - 2.86E+06 - - - 2.379 - 2.573 0.234 - 134.5 1 2 1 0.0033 12 0 0 0 1.37E+08 5.93E+06 - - - 3.7676 0.9967 221125_WJC_METTL3_EV_vs_WT_F07.09483.09483.3 0.0168 Sep-44 R.SIRPDNMSEYSK.Q "sp|Q92769|HDAC2_HUMAN,sp|Q13547|HDAC1_HUMAN,tr|E5RHE7|E5RHE7_HUMAN,tr|E5RGV4|E5RGV4_HUMAN,tr|H3BM24|H3BM24_HUMAN,tr|E5RJ04|E5RJ04_HUMAN,tr|E5RG37|E5RG37_HUMAN,tr|E5RH52|E5RH52_HUMAN,tr|E5RFP9|E5RFP9_HUMAN,tr|E5RFI6|E5RFI6_HUMAN,tr|Q5TEE2|Q5TEE2_HUMAN" 11 1425.6558 0.23 97521 9483 3 1425.65167 476.2259 Histone deacetylase 2 OS=Homo sapiens OX=9606 GN=HDAC2 PE=1 SV=2 5.79 1972.4 - 3.73E+06 - - - -2.9173 - 1.64 0.309 - 159.4 1 2 0 -0.0042 12 0 0 0 1.33E+09 5.83E+09 - - - 3.3551 0.9998 221125_WJC_METTL3_EV_vs_WT_F07.09484.09484.2 4.43E-06 24-Oct K.TQTPPVEENVTQK[136.11].L sp|Q6P1Q9|MET2B_HUMAN 1 1477.7504 0.8 97522 9484 2 1477.751957 739.8825 tRNA N(3)-methylcytidine methyltransferase METTL2B OS=Homo sapiens OX=9606 GN=METTL2B PE=1 SV=3 4.53 1972.5 - 248659 - - - 1.0617 - 2.094 0.53 - 286.7 1 2 0 0.0016 13 0 0 0 2.80E+06 3.53E+06 - - - 4.8519 0.9996 221125_WJC_METTL3_EV_vs_WT_F07.09487.09487.3 0.00215 13/56 R.FR[166.11]PAGAAPR[166.11]PPPK[136.11]PM.- "sp|Q5JNZ5|RS26L_HUMAN,sp|P62854|RS26_HUMAN" 2 1616.8968 1.04 97524 9487 3 1616.897402 539.9729 Putative 40S ribosomal protein S26-like 1 OS=Homo sapiens OX=9606 GN=RPS26P11 PE=5 SV=1 12.01 1972.8 - 588597 - - - 0.3865 - 1.868 0.342 - 147.2 1 2 0 0.0006 15 0 0 0 3.15E+07 3.03E+07 - - - 3.9833 0.9977 221125_WJC_METTL3_EV_vs_WT_F07.09489.09489.2 0.0775 22-Nov R.SIRPDNMSEYSK.Q "sp|Q92769|HDAC2_HUMAN,sp|Q13547|HDAC1_HUMAN,tr|E5RHE7|E5RHE7_HUMAN,tr|E5RGV4|E5RGV4_HUMAN,tr|H3BM24|H3BM24_HUMAN,tr|E5RJ04|E5RJ04_HUMAN,tr|E5RG37|E5RG37_HUMAN,tr|E5RH52|E5RH52_HUMAN,tr|E5RFP9|E5RFP9_HUMAN,tr|E5RFI6|E5RFI6_HUMAN,tr|Q5TEE2|Q5TEE2_HUMAN" 11 1425.6558 0.21 97525 9489 2 1425.65763 713.8352 Histone deacetylase 2 OS=Homo sapiens OX=9606 GN=HDAC2 PE=1 SV=2 5.79 1973 - 1.06E+06 - - - 1.2633 - 1.77 0.199 - 127 1 2 0 0.0018 12 0 0 0 2.83E+08 1.37E+09 - - - 2.0126 0.9912 221125_WJC_METTL3_EV_vs_WT_F07.09492.09492.2 0.0476 24-Nov K.DASLVVTTSGDHK[136.11].A "sp|Q13685|AAMP_HUMAN,tr|H7C0R2|H7C0R2_HUMAN,tr|C9JG97|C9JG97_HUMAN,tr|C9JEH3|C9JEH3_HUMAN" 4 1336.6714 0.53 97528 9492 2 1336.675728 669.343 Angio-associated migratory cell protein OS=Homo sapiens OX=9606 GN=AAMP PE=1 SV=2 5.21 1973.3 - 636262 - - - 3.2312 - 2.276 0.127 - 499.5 2 2 0 0.0043 13 0 0 0 1.40E+07 2.64E+07 - - - 1.954 0.9712 221125_WJC_METTL3_EV_vs_WT_F07.09499.09499.2 0.313 18-Aug R.KEEMDKLLDK.L sp|Q96SB3|NEB2_HUMAN 1 1247.6431 44.99 97534 9499 2 1247.643884 624.8288 Neurabin-2 OS=Homo sapiens OX=9606 GN=PPP1R9B PE=1 SV=3 4.78 1974.2 - 756979 - - - 0.5971 - 1.682 0.159 - 238.2 1 2 1 0.0007 10 0 0 0 1.37E+07 3.06E+05 - - - 1.6666 0.9988 221125_WJC_METTL3_EV_vs_WT_F07.09500.09500.3 0.00136 Dec-44 R.EKLTPEQLHSMR.Q "sp|Q9Y2R0|COA3_HUMAN,tr|K7EPV0|K7EPV0_HUMAN" 2 1467.7504 1.64 97535 9500 3 1467.752778 490.2574 "Cytochrome c oxidase assembly factor 3 homolog, mitochondrial OS=Homo sapiens OX=9606 GN=COA3 PE=1 SV=1" 6.86 1974.2 - 511497 - - - 1.6215 - 2.238 0.356 - 199.8 1 2 1 0.0024 12 0 0 0 1.45E+07 8.82E+06 - - - 4.7413 1 221125_WJC_METTL3_EV_vs_WT_F07.09501.09501.3 9.65E-06 Dec-48 K.DASLVVTTSGDHK.A "sp|Q13685|AAMP_HUMAN,tr|H7C0R2|H7C0R2_HUMAN,tr|C9JG97|C9JG97_HUMAN,tr|C9JEH3|C9JEH3_HUMAN" 4 1328.6572 0.98 97536 9501 3 1328.657306 443.893 Angio-associated migratory cell protein OS=Homo sapiens OX=9606 GN=AAMP PE=1 SV=2 5.21 1974.3 - 2.95E+06 - - - 0.073 - 2.346 0.498 - 176.8 1 2 0 0.0001 13 0 0 0 6.01E+07 6.14E+07 - - - 6.4041 0.9997 221125_WJC_METTL3_EV_vs_WT_F07.09502.09502.3 0.00189 Aug-48 K.DASLVVTTSGDHK[136.11].A "sp|Q13685|AAMP_HUMAN,tr|H7C0R2|H7C0R2_HUMAN,tr|C9JG97|C9JG97_HUMAN,tr|C9JEH3|C9JEH3_HUMAN" 4 1336.6714 1 97537 9502 3 1336.671736 446.5644 Angio-associated migratory cell protein OS=Homo sapiens OX=9606 GN=AAMP PE=1 SV=2 5.21 1974.3 - 2.51E+06 - - - 0.2446 - 1.562 0.406 - 75.3 1 2 0 0.0003 13 0 0 0 6.01E+07 6.04E+07 - - - 4.2756 0.9202 221125_WJC_METTL3_EV_vs_WT_F07.09503.09503.3 0.848 Aug-36 K.KNEFQGELEK.Q "sp|Q8NBJ4|GOLM1_HUMAN,tr|F8WAT9|F8WAT9_HUMAN,tr|C9J941|C9J941_HUMAN,tr|C9JYM4|C9JYM4_HUMAN" 4 1220.6037 1.86 97538 9503 3 1220.603455 407.8752 Golgi membrane protein 1 OS=Homo sapiens OX=9606 GN=GOLM1 PE=1 SV=1 4.79 1974.4 - 1.08E+06 - - - -0.2146 - 1.471 0.082 - 95.3 1 2 0 -0.0003 10 0 0 0 6.27E+07 3.37E+07 - - - 0.5813 0.9971 221125_WJC_METTL3_EV_vs_WT_F07.09504.09504.4 0.0231 18/84 R.FRPAGAAPRPPPKPM.- "sp|Q5JNZ5|RS26L_HUMAN,sp|P62854|RS26_HUMAN" 2 1588.866 1.25 97539 9504 4 1588.867174 398.2238 Putative 40S ribosomal protein S26-like 1 OS=Homo sapiens OX=9606 GN=RPS26P11 PE=5 SV=1 12.01 1974.5 - 1.03E+06 - - - 0.7156 - 1.812 0.251 - 152.5 1 2 0 0.0011 15 0 0 0 3.31E+07 2.65E+07 - - - 1.6231 0.9987 221125_WJC_METTL3_EV_vs_WT_F07.09506.09506.2 0.135 18-Jul K.K[136.11]NEFQGELEK[136.11].Q "sp|Q8NBJ4|GOLM1_HUMAN,tr|F8WAT9|F8WAT9_HUMAN,tr|C9J941|C9J941_HUMAN,tr|C9JYM4|C9JYM4_HUMAN" 4 1236.6321 2.87 97541 9506 2 1236.634047 619.3233 Golgi membrane protein 1 OS=Homo sapiens OX=9606 GN=GOLM1 PE=1 SV=1 4.79 1974.7 - 264804 - - - 1.5607 - 1.698 0.291 - 132.7 1 2 0 0.0019 10 0 0 0 3.64E+07 1.27E+07 - - - 2.6676 0.9982 221125_WJC_METTL3_EV_vs_WT_F07.09507.09507.2 0.00706 24-Jun K.TQTPPVEENVTQK.L sp|Q6P1Q9|MET2B_HUMAN 1 1469.7362 0.66 97542 9507 2 1469.736315 735.8754 tRNA N(3)-methylcytidine methyltransferase METTL2B OS=Homo sapiens OX=9606 GN=METTL2B PE=1 SV=3 4.53 1974.8 - 190226 - - - 0.0864 - 1.351 0.277 - 100.9 1 2 0 0.0001 13 0 0 0 2.21E+06 3.35E+06 - - - 1.859 0.9922 221125_WJC_METTL3_EV_vs_WT_F07.09511.09511.3 0.00012 13/36 Y.FHPPAHLQAK[136.11].L "sp|Q9NR56|MBNL1_HUMAN,sp|Q5VZF2|MBNL2_HUMAN,tr|H7C4T5|H7C4T5_HUMAN,tr|Q86VM6|Q86VM6_HUMAN,tr|H7C4Y1|H7C4Y1_HUMAN,tr|A0A0A0MQX8|A0A0A0MQX8_HUMAN,tr|A0A7P0T9I3|A0A7P0T9I3_HUMAN,tr|C9JCX1|C9JCX1_HUMAN,tr|C9JP00|C9JP00_HUMAN,tr|O95205|O95205_HUMAN" 10 1152.6284 1.79 97544 9511 3 1152.626709 385.2167 Muscleblind-like protein 1 OS=Homo sapiens OX=9606 GN=MBNL1 PE=1 SV=2 8.76 1975.4 - 339197 - - - -1.4341 - 2.079 0.451 - 243.6 1 1 0 -0.0017 10 0 0 0 6.16E+07 3.44E+07 - - - 5.7052 1 221125_WJC_METTL3_EV_vs_WT_F07.09512.09512.2 6.22E-05 16/26 R.GNLGAGNGNLQGPR[166.11].H "sp|P43243|MATR3_HUMAN,tr|D6RE02|D6RE02_HUMAN,tr|B3KM87|B3KM87_HUMAN,tr|A8MXP9|A8MXP9_HUMAN,tr|D6RAY2|D6RAY2_HUMAN,tr|D6R991|D6R991_HUMAN,tr|A0A0R4J2E8|A0A0R4J2E8_HUMAN,tr|D6RAM9|D6RAM9_HUMAN,tr|D6RIA2|D6RIA2_HUMAN,tr|H0Y8T4|H0Y8T4_HUMAN,tr|D6REM6|D6REM6_HUMAN,tr|D6RBI2|D6RBI2_HUMAN" 12 1333.6726 1.41 97545 9512 2 1333.672797 667.8436 Matrin-3 OS=Homo sapiens OX=9606 GN=MATR3 PE=1 SV=2 9.75 1975.4 - 1.74E+06 - - - 0.1252 - 2.756 0.563 - 886.4 1 2 0 0.0002 14 0 0 0 1.54E+08 1.09E+08 - - - 5.7433 0.9997 221125_WJC_METTL3_EV_vs_WT_F07.09516.09516.2 4.25E-05 Sep-38 R.AAAAAATAPPSPGPAQPGPR[166.11].A sp|Q6SPF0|SAMD1_HUMAN 1 1764.9147 3.95 97549 9516 2 1764.913797 883.4646 Sterile alpha motif domain-containing protein 1 OS=Homo sapiens OX=9606 GN=SAMD1 PE=1 SV=1 9.79 1975.8 - 197697 - - - -0.4839 - 2.124 0.39 - 120.1 1 2 0 -0.0009 20 0 0 0 1.66E+07 4.21E+06 - - - 3.7733 0.9643 221125_WJC_METTL3_EV_vs_WT_F07.09517.09517.2 7.26 24-May K.SSGSVASLPQSDR.S "sp|O75122|CLAP2_HUMAN,tr|E7ERI8|E7ERI8_HUMAN,tr|E7ENG2|E7ENG2_HUMAN,tr|A0A804HJG7|A0A804HJG7_HUMAN,tr|J3KR49|J3KR49_HUMAN,tr|B3KR06|B3KR06_HUMAN,tr|E7EW49|E7EW49_HUMAN,tr|E3W994|E3W994_HUMAN,tr|A0A0U1RQI6|A0A0U1RQI6_HUMAN" 9 1289.6212 1.58 97550 9517 2 1289.619855 645.8179 CLIP-associating protein 2 OS=Homo sapiens OX=9606 GN=CLASP2 PE=1 SV=3 5.55 1976 - 165141 - - - -1.0104 - 1.235 0.085 - 62.8 5 2 0 -0.0013 13 0 0 0 4.76E+06 3.02E+06 - - - -0.1021 0.9998 221125_WJC_METTL3_EV_vs_WT_F07.09518.09518.2 2.19E-05 Jun-32 K.ADPDGPEAQAEAC[160.03]SGER.T "sp|Q9NX24|NHP2_HUMAN,tr|J3QSY4|J3QSY4_HUMAN,tr|D6RCB9|D6RCB9_HUMAN,tr|D6RC52|D6RC52_HUMAN" 4 1758.7115 1.62 97551 9518 2 1758.714525 880.363 H\ACA ribonucleoprotein complex subunit 2 OS=Homo sapiens OX=9606 GN=NHP2 PE=1 SV=1 3.83 1976.1 - 87022 - - - 1.7166 - 1.554 0.665 - 61 1 2 0 0.003 17 0 0 0 1.84E+06 1.13E+06 - - - 5.0355 0.9975 221125_WJC_METTL3_EV_vs_WT_F07.09521.09521.3 0.00273 Sep-36 K.K[136.11]NEFQGELEK[136.11].Q "sp|Q8NBJ4|GOLM1_HUMAN,tr|F8WAT9|F8WAT9_HUMAN,tr|C9J941|C9J941_HUMAN,tr|C9JYM4|C9JYM4_HUMAN" 4 1236.6321 2.56 97552 9521 3 1236.63087 413.218 Golgi membrane protein 1 OS=Homo sapiens OX=9606 GN=GOLM1 PE=1 SV=1 4.79 1976.5 - 1.31E+06 - - - -1.0084 - 1.53 0.26 - 116.3 1 2 0 -0.0012 10 0 0 0 8.83E+07 3.45E+07 - - - 2.6804 0.9998 221125_WJC_METTL3_EV_vs_WT_F07.09526.09526.2 4.18E-05 28-Jul K.EASDPQPEEADGGLK[136.11].S sp|P52907|CAZA1_HUMAN 1 1549.6987 1.48 97557 9526 2 1549.700073 775.8566 F-actin-capping protein subunit alpha-1 OS=Homo sapiens OX=9606 GN=CAPZA1 PE=1 SV=3 3.83 1977.1 - 381995 - - - 0.8563 - 1.55 0.606 - 78.5 1 2 0 0.0013 15 0 0 0 2.11E+07 1.42E+07 - - - 4.594 0.9941 221125_WJC_METTL3_EV_vs_WT_F07.09535.09535.3 0.000147 14/40 K.YFHPPAHLQAK[136.11].L "sp|Q9NR56|MBNL1_HUMAN,sp|Q5VZF2|MBNL2_HUMAN,tr|H7C4T5|H7C4T5_HUMAN,tr|Q86VM6|Q86VM6_HUMAN,tr|H7C4Y1|H7C4Y1_HUMAN,tr|A0A0A0MQX8|A0A0A0MQX8_HUMAN,tr|A0A7P0T9I3|A0A7P0T9I3_HUMAN,tr|C9JCX1|C9JCX1_HUMAN,tr|C9JP00|C9JP00_HUMAN,tr|O95205|O95205_HUMAN" 10 1315.6917 1.54 97562 9535 3 1315.690622 439.5712 Muscleblind-like protein 1 OS=Homo sapiens OX=9606 GN=MBNL1 PE=1 SV=2 8.61 1978.1 - 1.04E+07 - - - -0.8125 - 2.338 0.106 - 228.9 1 2 0 -0.0011 11 0 0 0 6.21E+08 4.03E+08 - - - 2.1342 1 221125_WJC_METTL3_EV_vs_WT_F07.09536.09536.2 8.62E-06 14/28 K.GSC[160.03]GIGGGIGGGSSR.L "sp|P02533|K1C14_HUMAN,sp|P08779|K1C16_HUMAN,tr|K7ENV3|K7ENV3_HUMAN" 3 1277.5782 999 97563 9536 2 1277.576911 639.7964 "Keratin, type I cytoskeletal 14 OS=Homo sapiens OX=9606 GN=KRT14 PE=1 SV=4" 8.25 1978.1 - 1.38E+06 - - - -1.0457 - 2.389 0.623 - 420.5 1 2 0 -0.0013 15 0 0 0 4.48E+07 0.00E+00 - - - 5.7831 1 221125_WJC_METTL3_EV_vs_WT_F07.09537.09537.2 3.48E-09 28-Oct K.EASDPQPEEADGGLK.S sp|P52907|CAZA1_HUMAN 1 1541.6845 1.48 97564 9537 2 1541.682361 771.8495 F-actin-capping protein subunit alpha-1 OS=Homo sapiens OX=9606 GN=CAPZA1 PE=1 SV=3 3.83 1978.3 - 846956 - - - -1.4173 - 2.157 0.675 - 171.1 1 2 0 -0.0022 15 0 0 0 2.11E+07 1.42E+07 - - - 5.9158 1 221125_WJC_METTL3_EV_vs_WT_F07.09540.09540.2 5.84E-12 13/26 R.YGDGGSSFQSTTGH.C sp|P55795|HNRH2_HUMAN 1 1399.564 - 97567 9540 2 1399.564216 700.7893 Heterogeneous nuclear ribonucleoprotein H2 OS=Homo sapiens OX=9606 GN=HNRNPH2 PE=1 SV=1 5.08 1978.7 - 407111 - - - 0.1279 - 2.731 0.666 - 358.5 1 1 0 0.0002 14 0 0 0 - - - - - 6.4812 0.9999 221125_WJC_METTL3_EV_vs_WT_F07.09544.09544.3 0.00644 Dec-68 K.ALVSGK[136.11]PAESSAVAATEK[136.11].K sp|O95182|NDUA7_HUMAN 1 1730.9385 1.86 97569 9544 3 1730.934682 577.9868 NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 7 OS=Homo sapiens OX=9606 GN=NDUFA7 PE=1 SV=3 6.19 1979.1 - 1.21E+06 - - - -2.2225 - 2.689 0.435 - 99.5 1 2 0 -0.0038 18 0 0 0 5.33E+07 2.86E+07 - - - 5.8519 1 221125_WJC_METTL3_EV_vs_WT_F07.09547.09547.3 1.86E-07 17/68 K.ALVSGKPAESSAVAATEK.K sp|O95182|NDUA7_HUMAN 1 1714.9101 1.87 97572 9547 3 1714.907483 572.644 NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 7 OS=Homo sapiens OX=9606 GN=NDUFA7 PE=1 SV=3 6.19 1979.3 - 1.67E+06 - - - -1.5429 - 3.341 0.534 - 246.5 1 2 0 -0.0026 18 0 0 0 5.35E+07 2.86E+07 - - - 7.4966 0.9998 221125_WJC_METTL3_EV_vs_WT_F07.09548.09548.3 0.000763 13/48 R.LLDHRPVIQGETR.Y "sp|Q8TDH9|BL1S5_HUMAN,tr|G5E931|G5E931_HUMAN,tr|H3BN57|H3BN57_HUMAN,tr|A0A0D9SEU2|A0A0D9SEU2_HUMAN,tr|A0A0A0MTN6|A0A0A0MTN6_HUMAN" 5 1532.8423 2.02 97573 9548 3 1532.84091 511.9547 Biogenesis of lysosome-related organelles complex 1 subunit 5 OS=Homo sapiens OX=9606 GN=BLOC1S5 PE=1 SV=1 6.75 1979.4 - 968453 - - - -0.9231 - 2.084 0.362 - 196.2 1 2 0 -0.0014 13 0 0 0 1.43E+07 7.09E+06 - - - 4.5664 0.9998 221125_WJC_METTL3_EV_vs_WT_F07.09550.09550.2 1.47E-06 24-Nov K.QPC[160.03]QPPPVC[160.03]PTPK.C "sp|P22531|SPR2E_HUMAN,sp|P35326|SPR2A_HUMAN,sp|P22532|SPR2D_HUMAN,sp|P35325|SPR2B_HUMAN,sp|Q9BYE4|SPR2G_HUMAN" 5 1504.7167 999 97574 9550 2 1504.713599 753.3656 Small proline-rich protein 2E OS=Homo sapiens OX=9606 GN=SPRR2E PE=2 SV=2 8.06 1979.7 - 714497 - - - -2.0316 - 1.998 0.615 - 351.4 1 2 0 -0.0031 13 0 0 0 1.73E+07 0.00E+00 - - - 5.3588 1 221125_WJC_METTL3_EV_vs_WT_F07.09552.09552.3 6.20E-05 17/48 K.AFSQNSGLINHQR.L sp|P17028|ZNF24_HUMAN 1 1470.7328 0.73 97575 9552 3 1470.729738 491.2515 Zinc finger protein 24 OS=Homo sapiens OX=9606 GN=ZNF24 PE=1 SV=4 9.8 1979.9 - 1.62E+06 - - - -2.0643 - 3.239 0.519 - 273.8 1 2 0 -0.003 13 0 0 0 5.59E+07 7.69E+07 - - - 7.512 1 221125_WJC_METTL3_EV_vs_WT_F07.09554.09554.3 2.94E-09 20/52 R.IVEDEPNK[136.11]IC[160.03]EADR[166.11].V sp|P55060|XPO2_HUMAN 1 1704.8108 0.92 97577 9554 3 1704.810676 569.2775 Exportin-2 OS=Homo sapiens OX=9606 GN=CSE1L PE=1 SV=3 4.18 1980.1 - 1.94E+06 - - - -0.0551 - 3.173 0.59 - 489.5 1 2 1 -0.0001 14 0 0 0 9.99E+07 1.08E+08 - - - 8.1865 0.9986 221125_WJC_METTL3_EV_vs_WT_F07.09555.09555.2 0.000114 20-Oct K.YFHPPAHLQAK[136.11].L "sp|Q9NR56|MBNL1_HUMAN,sp|Q5VZF2|MBNL2_HUMAN,tr|H7C4T5|H7C4T5_HUMAN,tr|Q86VM6|Q86VM6_HUMAN,tr|H7C4Y1|H7C4Y1_HUMAN,tr|A0A0A0MQX8|A0A0A0MQX8_HUMAN,tr|A0A7P0T9I3|A0A7P0T9I3_HUMAN,tr|C9JCX1|C9JCX1_HUMAN,tr|C9JP00|C9JP00_HUMAN,tr|O95205|O95205_HUMAN" 10 1315.6917 1.38 97578 9555 2 1315.688652 658.8531 Muscleblind-like protein 1 OS=Homo sapiens OX=9606 GN=MBNL1 PE=1 SV=2 8.61 1980.2 - 740066 - - - -2.3098 - 1.932 0.294 - 257.6 1 2 0 -0.003 11 0 0 0 2.79E+07 2.02E+07 - - - 2.9931 0.9999 221125_WJC_METTL3_EV_vs_WT_F07.09557.09557.3 1.09E-05 15/44 R.HILEAPQHGLER.R sp|Q9NVK5|FGOP2_HUMAN 1 1398.7368 0.67 97580 9557 3 1398.737558 467.2529 FGFR1 oncogene partner 2 OS=Homo sapiens OX=9606 GN=FGFR1OP2 PE=1 SV=1 6 1980.4 - 698798 - - - 0.5441 - 2.451 0.423 - 251.4 1 2 0 0.0008 12 0 0 0 2.86E+07 4.27E+07 - - - 5.7408 1 221125_WJC_METTL3_EV_vs_WT_F07.09558.09558.3 7.77E-06 Dec-36 K.THEDIEAQIR.E "sp|O75533|SF3B1_HUMAN,tr|B4DGZ4|B4DGZ4_HUMAN,tr|F8WC19|F8WC19_HUMAN,tr|A0A494C1M2|A0A494C1M2_HUMAN" 4 1210.5942 0.18 97581 9558 3 1210.592418 404.5387 Splicing factor 3B subunit 1 OS=Homo sapiens OX=9606 GN=SF3B1 PE=1 SV=3 4.65 1980.6 - 538565 - - - -1.4844 - 2.547 0.509 - 350.2 1 2 0 -0.0018 10 0 0 0 2.27E+07 1.25E+08 - - - 6.9447 1 221125_WJC_METTL3_EV_vs_WT_F07.09568.09568.3 8.22E-07 16/40 R.ENPPVK[136.11]PDFSK[136.11].L sp|Q9Y294|ASF1A_HUMAN 1 1272.6685 0.98 97588 9568 3 1272.670583 425.2301 Histone chaperone ASF1A OS=Homo sapiens OX=9606 GN=ASF1A PE=1 SV=1 6.17 1981.8 - 588908 - - - 1.6351 - 2.664 0.521 - 351.8 1 2 0 0.0021 11 0 0 0 6.18E+07 6.31E+07 - - - 7.1316 0.9925 221125_WJC_METTL3_EV_vs_WT_F07.09570.09570.3 2.45E-08 13/56 A.AAGYPGQQQNFHSVR.E sp|Q12948|FOXC1_HUMAN 1 1658.7914 1.08 97590 9570 3 1658.786826 553.9377 Forkhead box protein C1 OS=Homo sapiens OX=9606 GN=FOXC1 PE=1 SV=3 8.8 1982.1 - 311033 - - - -2.7285 - 2.505 0.53 - 181.6 1 1 0 -0.0045 15 0 0 0 8.18E+06 7.60E+06 - - - 6.8439 0.9991 221125_WJC_METTL3_EV_vs_WT_F07.09573.09573.2 0.000331 28-Sep R.YQSAPSQAPGNTIER.G sp|Q86XZ4|SPAS2_HUMAN 1 1617.7747 1.55 97591 9573 2 1617.779541 809.8946 Spermatogenesis-associated serine-rich protein 2 OS=Homo sapiens OX=9606 GN=SPATS2 PE=1 SV=1 6 1982.4 - 645552 - - - 2.9936 - 1.819 0.48 - 227.5 1 2 0 0.0048 15 0 0 0 8.17E+06 5.26E+06 - - - 4.0557 0.9999 221125_WJC_METTL3_EV_vs_WT_F07.09576.09576.3 4.71E-07 14/40 R.ENPPVKPDFSK.L sp|Q9Y294|ASF1A_HUMAN 1 1256.6401 0.99 97594 9576 3 1256.636543 419.8873 Histone chaperone ASF1A OS=Homo sapiens OX=9606 GN=ASF1A PE=1 SV=1 6.17 1982.8 - 732746 - - - -2.8322 - 2.491 0.484 - 339 1 2 0 -0.0036 11 0 0 0 6.18E+07 6.22E+07 - - - 6.5279 0.9999 221125_WJC_METTL3_EV_vs_WT_F07.09581.09581.2 3.45E-06 13/18 K.THEDIEAQIR.E "sp|O75533|SF3B1_HUMAN,tr|B4DGZ4|B4DGZ4_HUMAN,tr|F8WC19|F8WC19_HUMAN,tr|A0A494C1M2|A0A494C1M2_HUMAN" 4 1210.5942 0.26 97597 9581 2 1210.593324 606.3044 Splicing factor 3B subunit 1 OS=Homo sapiens OX=9606 GN=SF3B1 PE=1 SV=3 4.65 1983.4 - 665376 - - - -0.736 - 2.251 0.553 - 523.4 1 2 0 -0.0009 10 0 0 0 1.26E+07 4.88E+07 - - - 5.39 1 221125_WJC_METTL3_EV_vs_WT_F07.09583.09583.2 9.60E-10 26-Dec R.IVEDEPNK[136.11]IC[160.03]EADR[166.11].V sp|P55060|XPO2_HUMAN 1 1704.8108 0.82 97599 9583 2 1704.810858 853.4127 Exportin-2 OS=Homo sapiens OX=9606 GN=CSE1L PE=1 SV=3 4.18 1983.7 - 317340 - - - 0.0516 - 2.637 0.651 - 424.8 1 2 1 0.0001 14 0 0 0 6.54E+06 8.01E+06 - - - 6.2825 1 221125_WJC_METTL3_EV_vs_WT_F07.09584.09584.2 2.11E-07 16/26 R.IVEDEPNKIC[160.03]EADR.V sp|P55060|XPO2_HUMAN 1 1686.7883 0.82 97600 9584 2 1686.788378 844.4014 Exportin-2 OS=Homo sapiens OX=9606 GN=CSE1L PE=1 SV=3 4.18 1983.8 - 306180 - - - 0.0462 - 2.887 0.597 - 795.6 1 2 1 0.0001 14 0 0 0 6.54E+06 8.01E+06 - - - 6.111 1 221125_WJC_METTL3_EV_vs_WT_F07.09589.09589.3 2.20E-06 13/48 K.AFSQNSGLINHQR[166.11].L sp|P17028|ZNF24_HUMAN 1 1480.741 0.74 97602 9589 3 1480.7395 494.5876 Zinc finger protein 24 OS=Homo sapiens OX=9606 GN=ZNF24 PE=1 SV=4 9.8 1984.4 - 4.66E+06 - - - -1.0427 - 2.457 0.573 - 160.6 1 2 0 -0.0015 13 0 0 0 5.71E+07 7.70E+07 - - - 7.3652 0.9985 221125_WJC_METTL3_EV_vs_WT_F07.09590.09590.3 0.093 Oct-36 K.TSLK[136.11]PAHLLR[166.11].H sp|Q8N0Y2|ZN444_HUMAN 1 1152.7098 0.01 97603 9590 3 1152.708523 385.2439 Zinc finger protein 444 OS=Homo sapiens OX=9606 GN=ZNF444 PE=1 SV=1 11 1984.5 - 2.15E+06 - - - -1.1052 - 1.997 0.224 - 144.4 1 2 0 -0.0013 10 0 0 0 1.88E+05 2.81E+07 - - - 3.0569 0.9359 221125_WJC_METTL3_EV_vs_WT_F07.09592.09592.2 0.0994 16-Jul R.K[136.11]QDSGHLDL.R "sp|Q86U44|MTA70_HUMAN,tr|B4E349|B4E349_HUMAN,tr|F5H6D8|F5H6D8_HUMAN,tr|B4DTN4|B4DTN4_HUMAN" 4 1019.5127 0.03 97605 9592 2 1019.512969 510.7636 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 5.21 1984.7 - 1.03E+06 - - - 0.2413 - 1.326 0.328 - 131.5 1 1 0 0.0002 9 0 0 0 1.84E+06 5.36E+07 - - - 2.2799 0.9999 221125_WJC_METTL3_EV_vs_WT_F07.09597.09597.3 0.00191 14/44 R.YQIDDK[136.11]PNNQIR[166.11].L sp|Q9NP92|RT30_HUMAN 1 1520.7702 1.14 97608 9597 3 1520.767436 507.9307 "39S ribosomal protein S30, mitochondrial OS=Homo sapiens OX=9606 GN=MRPS30 PE=1 SV=2" 5.96 1985.4 - 663529 - - - -1.8339 - 2.553 0.439 - 154.6 1 2 0 -0.0028 12 0 0 0 1.76E+07 1.54E+07 - - - 6.0316 0.9999 221125_WJC_METTL3_EV_vs_WT_F07.09599.09599.3 0.000174 Dec-36 R.KNNIPANFTR.S "sp|Q96QD9|UIF_HUMAN,tr|H9KVC6|H9KVC6_HUMAN" 2 1173.6255 0.5 97610 9599 3 1173.624103 392.2158 UAP56-interacting factor OS=Homo sapiens OX=9606 GN=FYTTD1 PE=1 SV=3 11 1985.7 - 760629 - - - -1.152 - 2.278 0.36 - 243.2 1 2 0 -0.0014 10 0 0 0 1.19E+07 2.39E+07 - - - 4.9577 1 221125_WJC_METTL3_EV_vs_WT_F07.09603.09603.2 7.05E-10 13/24 K.TFQGPNC[160.03]PATC[160.03]GR[166.11].V "sp|Q13685|AAMP_HUMAN,tr|C9JG97|C9JG97_HUMAN,tr|C9JEH3|C9JEH3_HUMAN,tr|C9JTS3|C9JTS3_HUMAN" 4 1474.6321 0.7 97614 9603 2 1474.632536 738.3233 Angio-associated migratory cell protein OS=Homo sapiens OX=9606 GN=AAMP PE=1 SV=2 7.75 1986.2 - 374072 - - - 0.3038 - 2.545 0.588 - 563 1 2 0 0.0004 13 0 0 0 6.38E+06 9.10E+06 - - - 5.7813 0.9993 221125_WJC_METTL3_EV_vs_WT_F07.09604.09604.3 5.05E-05 Oct-44 R.GSDASGQLFHGR[166.11].A "sp|P19174|PLCG1_HUMAN,tr|V9GYH5|V9GYH5_HUMAN,tr|V9GY71|V9GY71_HUMAN" 3 1240.5824 1.17 97615 9604 3 1240.582372 414.5347 "1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma-1 OS=Homo sapiens OX=9606 GN=PLCG1 PE=1 SV=1" 6.74 1986.3 - 366713 - - - -0.0371 - 2 0.275 - 130.2 1 2 0 0 12 0 0 0 1.08E+07 9.25E+06 - - - 3.5273 0.999 221125_WJC_METTL3_EV_vs_WT_F07.09605.09605.2 0.000346 20-Jul R.ENPPVKPDFSK.L sp|Q9Y294|ASF1A_HUMAN 1 1256.6401 1.15 97616 9605 2 1256.636752 629.3273 Histone chaperone ASF1A OS=Homo sapiens OX=9606 GN=ASF1A PE=1 SV=1 6.17 1986.5 - 252203 - - - -2.6658 - 1.683 0.434 - 158.1 1 2 0 -0.0034 11 0 0 0 5.92E+06 5.14E+06 - - - 3.6538 0.9968 221125_WJC_METTL3_EV_vs_WT_F07.09606.09606.2 8.53E-07 24-Oct K.TFQGPNC[160.03]PATC[160.03]GR.V "sp|Q13685|AAMP_HUMAN,tr|C9JG97|C9JG97_HUMAN,tr|C9JEH3|C9JEH3_HUMAN,tr|C9JTS3|C9JTS3_HUMAN" 4 1464.6238 0.55 97617 9606 2 1464.615117 733.3192 Angio-associated migratory cell protein OS=Homo sapiens OX=9606 GN=AAMP PE=1 SV=2 7.75 1986.6 - 353052 - - - -5.9408 - 1.805 0.679 - 234.2 1 2 0 -0.0087 13 0 0 0 2.87E+06 5.25E+06 - - - 5.5691 0.9997 221125_WJC_METTL3_EV_vs_WT_F07.09607.09607.2 2.23E-07 30-Dec K.AVASPEATVSQTDENK.A "sp|Q641Q2|WAC2A_HUMAN,sp|Q9Y4E1|WAC2C_HUMAN,tr|F8W7U3|F8W7U3_HUMAN,tr|J3KP36|J3KP36_HUMAN,tr|E7ESD2|E7ESD2_HUMAN,tr|A0A0A0MR88|A0A0A0MR88_HUMAN,tr|A0A087WYF6|A0A087WYF6_HUMAN,tr|A0A096LPC5|A0A096LPC5_HUMAN" 8 1645.7795 4.8 97618 9607 2 1645.775895 823.897 WASH complex subunit 2A OS=Homo sapiens OX=9606 GN=WASHC2A PE=1 SV=3 4.14 1986.7 - 182566 - - - -2.1959 - 2.484 0.513 - 443.3 1 2 0 -0.0036 16 0 0 0 7.36E+06 1.53E+06 - - - 5.0658 0.9999 221125_WJC_METTL3_EV_vs_WT_F07.09610.09610.2 3.89E-08 26-Nov K.AVTEQGAELSNEER.N "sp|P27348|1433T_HUMAN,tr|E9PG15|E9PG15_HUMAN" 2 1531.7114 3.21 97621 9610 2 1531.711259 766.863 14-3-3 protein theta OS=Homo sapiens OX=9606 GN=YWHAQ PE=1 SV=1 4.09 1987.1 - 126407 - - - -0.1116 - 2.487 0.58 - 398.9 1 2 0 -0.0002 14 0 0 0 3.39E+06 1.06E+06 - - - 5.6111 0.9998 221125_WJC_METTL3_EV_vs_WT_F07.09613.09613.3 0.00225 Dec-40 K.DLEAHIDSANK[136.11].N sp|P35579|MYH9_HUMAN 1 1219.5924 0.91 97622 9613 3 1219.593246 407.5381 Myosin-9 OS=Homo sapiens OX=9606 GN=MYH9 PE=1 SV=4 4.54 1987.5 - 3.58E+06 - - - 0.6691 - 2.02 0.361 - 146.3 1 2 0 0.0008 11 0 0 0 1.03E+08 1.12E+08 - - - 4.5619 0.9999 221125_WJC_METTL3_EV_vs_WT_F07.09616.09616.3 2.40E-08 Dec-52 K.YEDFK[136.11]EEGSENAVK[136.11].A "sp|Q9NTK5|OLA1_HUMAN,tr|J3KQ32|J3KQ32_HUMAN" 2 1659.7599 1 97625 9616 3 1659.757894 554.2606 Obg-like ATPase 1 OS=Homo sapiens OX=9606 GN=OLA1 PE=1 SV=2 4.25 1987.8 - 832438 - - - -1.2062 - 2.246 0.608 - 83 1 2 1 -0.002 14 0 0 0 9.37E+06 9.37E+06 - - - 7.4684 0.9999 221125_WJC_METTL3_EV_vs_WT_F07.09617.09617.3 1.10E-06 15/52 K.YEDFKEEGSENAVK.A "sp|Q9NTK5|OLA1_HUMAN,tr|J3KQ32|J3KQ32_HUMAN" 2 1643.7315 1.32 97626 9617 3 1643.733837 548.9178 Obg-like ATPase 1 OS=Homo sapiens OX=9606 GN=OLA1 PE=1 SV=2 4.25 1987.9 - 684311 - - - 1.4242 - 2.835 0.599 - 146 1 2 1 0.0023 14 0 0 0 1.24E+07 9.37E+06 - - - 7.9869 0.9999 221125_WJC_METTL3_EV_vs_WT_F07.09625.09625.2 0.185 15/28 K.QGGGGGGGSVPGIER[166.11].M "sp|P52272|HNRPM_HUMAN,tr|M0R019|M0R019_HUMAN,tr|A0A087X0X3|A0A087X0X3_HUMAN,tr|M0R2T0|M0R2T0_HUMAN" 4 1293.6301 1.69 97634 9625 2 1293.631083 647.8223 Heterogeneous nuclear ribonucleoprotein M OS=Homo sapiens OX=9606 GN=HNRNPM PE=1 SV=3 6 1988.9 - 102344 - - - 0.7622 - 2.87 0.454 - 572 1 2 0 0.001 15 0 0 0 1.90E+09 1.13E+09 - - - 4.986 0.9999 221125_WJC_METTL3_EV_vs_WT_F07.09628.09628.2 0.000254 14/22 R.RTEEGPTLSYGR.D "sp|P43243|MATR3_HUMAN,tr|A8MXP9|A8MXP9_HUMAN,tr|D6R991|D6R991_HUMAN,tr|A0A0R4J2E8|A0A0R4J2E8_HUMAN,tr|D6REM6|D6REM6_HUMAN" 5 1364.6684 1.36 97635 9628 2 1364.669848 683.3415 Matrin-3 OS=Homo sapiens OX=9606 GN=MATR3 PE=1 SV=2 6.14 1989.3 - 1.50E+06 - - - 1.0303 - 2.726 0.492 - 158.4 1 2 0 0.0014 12 0 0 0 7.77E+08 5.70E+08 - - - 5.3131 0.9573 221125_WJC_METTL3_EV_vs_WT_F07.09629.09629.2 0.018 28-Jul K.VASVESQGQEISGNR.R "sp|Q5VU43|MYOME_HUMAN,tr|E9PQG4|E9PQG4_HUMAN,tr|A0A087WX83|A0A087WX83_HUMAN,tr|A0A075B749|A0A075B749_HUMAN" 4 1559.754 9.86 97636 9629 2 1559.763405 780.8843 Myomegalin OS=Homo sapiens OX=9606 GN=PDE4DIP PE=1 SV=3 4.53 1989.5 - 130358 - - - 6.0535 - 1.273 0.359 - 31.4 1 2 0 0.0094 15 0 0 0 1.43E+06 1.45E+05 - - - 2.283 1 221125_WJC_METTL3_EV_vs_WT_F07.09630.09630.3 0.000145 Nov-44 R.YQIDDKPNNQIR.L sp|Q9NP92|RT30_HUMAN 1 1502.7478 1.08 97637 9630 3 1502.748932 501.9232 "39S ribosomal protein S30, mitochondrial OS=Homo sapiens OX=9606 GN=MRPS30 PE=1 SV=2" 5.96 1989.5 - 2.08E+06 - - - 0.7832 - 2.427 0.444 - 91.5 1 2 0 0.0012 12 0 0 0 1.76E+07 1.63E+07 - - - 5.9475 0.9414 221125_WJC_METTL3_EV_vs_WT_F07.09631.09631.3 0.011 Aug-48 R.SEQAVAQLEEEKK.H "sp|Q9NSK0|KLC4_HUMAN,tr|C9JZE5|C9JZE5_HUMAN,tr|C9J8T5|C9J8T5_HUMAN" 3 1487.7468 8.83 97638 9631 3 1487.748117 496.9229 Kinesin light chain 4 OS=Homo sapiens OX=9606 GN=KLC4 PE=1 SV=3 4.49 1989.6 - 905070 - - - 0.9175 - 1.928 0.078 - 56.8 7 2 0 0.0014 13 0 0 0 1.41E+07 1.60E+06 - - - 0.798 0.9997 221125_WJC_METTL3_EV_vs_WT_F07.09632.09632.2 0.000941 20-Jul R.ENPPVK[136.11]PDFSK[136.11].L sp|Q9Y294|ASF1A_HUMAN 1 1272.6685 1.15 97639 9632 2 1272.669338 637.3415 Histone chaperone ASF1A OS=Homo sapiens OX=9606 GN=ASF1A PE=1 SV=1 6.17 1989.7 - 327862 - - - 0.6569 - 1.591 0.484 - 134.5 1 2 0 0.0008 11 0 0 0 5.92E+06 5.14E+06 - - - 3.8718 0.9995 221125_WJC_METTL3_EV_vs_WT_F07.09633.09633.2 6.84E-07 24-Nov R.SNVPSASEVPDNR.A "sp|Q9H992|MARH7_HUMAN,tr|F5H6W4|F5H6W4_HUMAN" 2 1370.6426 1.98 97640 9633 2 1370.638033 686.3286 E3 ubiquitin-protein ligase MARCHF7 OS=Homo sapiens OX=9606 GN=MARCHF7 PE=1 SV=1 4.37 1989.8 - 240802 - - - -3.3481 - 2.276 0.596 - 365.7 1 2 0 -0.0046 13 0 0 0 1.45E+07 7.34E+06 - - - 5.5524 0.98 221125_WJC_METTL3_EV_vs_WT_F07.09634.09634.3 1.49 Jul-64 R.VIPEDGPAAQNPENVK[136.11]R[166.11].L "sp|Q02218|ODO1_HUMAN,tr|E9PFG7|E9PFG7_HUMAN,tr|E9PDF2|E9PDF2_HUMAN,tr|A0A0D9SFS3|A0A0D9SFS3_HUMAN,tr|E9PCR7|E9PCR7_HUMAN" 5 1850.9605 2.14 97641 9634 3 1850.957674 617.9941 "2-oxoglutarate dehydrogenase, mitochondrial OS=Homo sapiens OX=9606 GN=OGDH PE=1 SV=3" 4.68 1990 - 201970 - - - -1.5511 - 1.31 0.21 - 42.7 1 2 0 -0.0029 17 0 0 0 2.43E+06 1.14E+06 - - - 1.5627 0.9421 221125_WJC_METTL3_EV_vs_WT_F07.09642.09642.3 0.332 Jun-48 R.GFSNSSNLC[160.03]MHQR.V sp|Q8N3J9|ZN664_HUMAN 1 1536.6562 1.17 97647 9642 3 1536.657433 513.226 Zinc finger protein 664 OS=Homo sapiens OX=9606 GN=ZNF664 PE=1 SV=1 8.26 1991 - 192576 - - - 0.8154 - 1.118 0.174 - 22.2 1 2 0 0.0013 13 0 0 0 1.79E+06 1.53E+06 - - - 0.782 0.9988 221125_WJC_METTL3_EV_vs_WT_F07.09643.09643.2 0.00225 26-Jun K.SNTEPQSPPIASPK[136.11].A "sp|P82094|TMF1_HUMAN,tr|F8WF45|F8WF45_HUMAN,tr|A0A2R8Y7M0|A0A2R8Y7M0_HUMAN" 3 1459.7398 2.23 97648 9643 2 1459.742033 730.8772 TATA element modulatory factor OS=Homo sapiens OX=9606 GN=TMF1 PE=1 SV=2 5.72 1991.1 - 115615 - - - 1.514 - 1.307 0.407 - 72.2 1 2 0 0.0022 14 0 0 0 2.46E+07 1.10E+07 - - - 2.7183 0.9996 221125_WJC_METTL3_EV_vs_WT_F07.09657.09657.2 0.0028 22-Nov R.R[166.11]TEEGPTLSYGR[166.11].D "sp|P43243|MATR3_HUMAN,tr|A8MXP9|A8MXP9_HUMAN,tr|D6R991|D6R991_HUMAN,tr|A0A0R4J2E8|A0A0R4J2E8_HUMAN,tr|D6REM6|D6REM6_HUMAN" 5 1384.685 1.36 97658 9657 2 1384.683982 693.3498 Matrin-3 OS=Homo sapiens OX=9606 GN=MATR3 PE=1 SV=2 6.14 1992.9 - 9.69E+06 - - - -0.7222 - 1.771 0.394 - 94.9 1 2 0 -0.001 12 0 0 0 7.76E+08 5.70E+08 - - - 3.4546 0.9993 221125_WJC_METTL3_EV_vs_WT_F07.09660.09660.3 0.0703 Dec-40 R.TAIHEVMEQGR[166.11].V "sp|P25205|MCM3_HUMAN,tr|J3KQ69|J3KQ69_HUMAN,tr|A0A499FHX9|A0A499FHX9_HUMAN" 3 1279.6218 0.65 97661 9660 3 1279.622096 427.5479 DNA replication licensing factor MCM3 OS=Homo sapiens OX=9606 GN=MCM3 PE=1 SV=3 5.37 1993.3 - 764119 - - - 0.2001 - 1.961 0.284 - 257.7 1 2 0 0.0003 11 0 0 0 3.54E+06 5.41E+06 - - - 3.6194 0.9999 221125_WJC_METTL3_EV_vs_WT_F07.09662.09662.2 3.71E-06 26-Nov R.LQETSSQSYVEEQK[136.11].Q "sp|Q8N9T8|KRI1_HUMAN,tr|F8WFC1|F8WFC1_HUMAN,tr|H0YFD2|H0YFD2_HUMAN,tr|A0A494C108|A0A494C108_HUMAN" 4 1662.7828 1.03 97663 9662 2 1662.784282 832.3987 Protein KRI1 homolog OS=Homo sapiens OX=9606 GN=KRI1 PE=1 SV=3 4.25 1993.5 - 208412 - - - 0.8853 - 2.533 0.52 - 348 1 2 0 0.0015 14 0 0 0 9.31E+06 9.01E+06 - - - 5.2136 1 221125_WJC_METTL3_EV_vs_WT_F07.09664.09664.2 1.24E-07 15/20 K.DLEAHIDSANK[136.11].N sp|P35579|MYH9_HUMAN 1 1219.5924 0.94 97664 9664 2 1219.591929 610.8035 Myosin-9 OS=Homo sapiens OX=9606 GN=MYH9 PE=1 SV=4 4.54 1993.7 - 1.23E+06 - - - -0.4108 - 3.152 0.644 - 730.1 1 2 0 -0.0005 11 0 0 0 4.32E+07 4.60E+07 - - - 6.9031 1 221125_WJC_METTL3_EV_vs_WT_F07.09670.09670.2 8.56E-06 26-Nov R.LQETSSQSYVEEQK.Q "sp|Q8N9T8|KRI1_HUMAN,tr|F8WFC1|F8WFC1_HUMAN,tr|H0YFD2|H0YFD2_HUMAN,tr|A0A494C108|A0A494C108_HUMAN" 4 1654.7686 1.03 97669 9670 2 1654.768907 828.3916 Protein KRI1 homolog OS=Homo sapiens OX=9606 GN=KRI1 PE=1 SV=3 4.25 1994.4 - 414211 - - - 0.1795 - 2.568 0.602 - 371.8 1 2 0 0.0003 14 0 0 0 9.31E+06 9.01E+06 - - - 5.854 1 221125_WJC_METTL3_EV_vs_WT_F07.09678.09678.3 1.48E-08 16/56 R.SFGGGC[160.03]HVTAAVSSR[166.11].R "sp|Q9NRA8|4ET_HUMAN,tr|B1AKL5|B1AKL5_HUMAN,tr|B1AKL4|B1AKL4_HUMAN" 3 1501.6971 1.13 97675 9678 3 1501.695905 501.573 Eukaryotic translation initiation factor 4E transporter OS=Homo sapiens OX=9606 GN=EIF4ENIF1 PE=1 SV=2 7.99 1995.3 - 821004 - - - -0.8164 - 2.508 0.63 - 191.9 1 2 0 -0.0012 15 0 0 0 2.08E+08 1.83E+08 - - - 7.9628 0.9973 221125_WJC_METTL3_EV_vs_WT_F07.09684.09684.3 0.000248 Nov-40 K.DK[136.11]DAYSSFGSR[166.11].S "sp|O00571|DDX3X_HUMAN,sp|O15523|DDX3Y_HUMAN,tr|A0A2R8YFR4|A0A2R8YFR4_HUMAN,tr|A0A2R8YCW1|A0A2R8YCW1_HUMAN,tr|A0A2R8YDH3|A0A2R8YDH3_HUMAN,tr|A0A2R8Y645|A0A2R8Y645_HUMAN,tr|A0A2R8YF78|A0A2R8YF78_HUMAN,tr|C9J8G5|C9J8G5_HUMAN,tr|A0A2R8YCU0|A0A2R8YCU0_HUMAN,tr|A0A0D9SFB3|A0A0D9SFB3_HUMAN,tr|A0A2R8YFS5|A0A2R8YFS5_HUMAN,tr|A0A0D9SF53|A0A0D9SF53_HUMAN,tr|A0A2R8Y650|A0A2R8Y650_HUMAN,tr|A0A087WX09|A0A087WX09_HUMAN,tr|C9J081|C9J081_HUMAN,tr|A0A2R8Y5G6|A0A2R8Y5G6_HUMAN,tr|A0A0D9SG12|A0A0D9SG12_HUMAN,tr|F6S8Q4|F6S8Q4_HUMAN,tr|A0A2U3TZJ9|A0A2U3TZJ9_HUMAN,tr|A0A2R8Y4A4|A0A2R8Y4A4_HUMAN,tr|A0A2R8YF89|A0A2R8YF89_HUMAN" 21 1249.5694 0.98 97679 9684 3 1249.564582 417.5304 ATP-dependent RNA helicase DDX3X OS=Homo sapiens OX=9606 GN=DDX3X PE=1 SV=3 5.96 1996 - 1.40E+06 - - - -3.8557 - 1.633 0.488 - 167.4 1 2 1 -0.0048 11 0 0 0 1.38E+08 1.40E+08 - - - 5.3726 1 221125_WJC_METTL3_EV_vs_WT_F07.09687.09687.3 1.33E-10 20/60 K.VDDEPMDVDKGPGSTK.E "sp|Q13123|RED_HUMAN,tr|A0A0C4DGW5|A0A0C4DGW5_HUMAN" 2 1688.7563 1.37 97682 9687 3 1688.747673 563.9261 Protein Red OS=Homo sapiens OX=9606 GN=IK PE=1 SV=3 4.04 1996.4 - 561954 - - - -5.1268 - 3.502 0.684 - 572.4 1 2 1 -0.0087 16 0 0 0 1.31E+07 9.56E+06 - - - 9.3794 1 221125_WJC_METTL3_EV_vs_WT_F07.09689.09689.2 2.10E-07 22-Dec R.GC[160.03]C[160.03]QEEAQFETK[136.11].K "sp|O60613|SEP15_HUMAN,tr|A0A3B3IT39|A0A3B3IT39_HUMAN,tr|A8MZD0|A8MZD0_HUMAN,tr|A0A087X1G7|A0A087X1G7_HUMAN,tr|A0A0J9YX89|A0A0J9YX89_HUMAN,tr|A0A087WXL0|A0A087WXL0_HUMAN" 6 1493.6006 0.04 97684 9689 2 1493.596539 747.8076 Selenoprotein F OS=Homo sapiens OX=9606 GN=SELENOF PE=1 SV=4 4.25 1996.7 - 508253 - - - -2.7383 - 2.475 0.613 - 740.3 1 2 0 -0.0041 12 0 0 0 1.11E+06 2.96E+07 - - - 5.9518 0.9998 221125_WJC_METTL3_EV_vs_WT_F07.09693.09693.3 8.00E-06 Nov-56 R.SFGGGC[160.03]HVTAAVSSR.R "sp|Q9NRA8|4ET_HUMAN,tr|B1AKL5|B1AKL5_HUMAN,tr|B1AKL4|B1AKL4_HUMAN" 3 1491.6889 1.13 97686 9693 3 1491.686752 498.2369 Eukaryotic translation initiation factor 4E transporter OS=Homo sapiens OX=9606 GN=EIF4ENIF1 PE=1 SV=2 7.99 1997.2 - 5.17E+06 - - - -1.4138 - 1.901 0.41 - 83.6 1 2 0 -0.0021 15 0 0 0 2.08E+08 1.83E+08 - - - 4.7867 0.9999 221125_WJC_METTL3_EV_vs_WT_F07.09694.09694.3 2.85E-06 Dec-40 K.DKDAYSSFGSR.S "sp|O00571|DDX3X_HUMAN,sp|O15523|DDX3Y_HUMAN,tr|A0A2R8YFR4|A0A2R8YFR4_HUMAN,tr|A0A2R8YCW1|A0A2R8YCW1_HUMAN,tr|A0A2R8YDH3|A0A2R8YDH3_HUMAN,tr|A0A2R8Y645|A0A2R8Y645_HUMAN,tr|A0A2R8YF78|A0A2R8YF78_HUMAN,tr|C9J8G5|C9J8G5_HUMAN,tr|A0A2R8YCU0|A0A2R8YCU0_HUMAN,tr|A0A0D9SFB3|A0A0D9SFB3_HUMAN,tr|A0A2R8YFS5|A0A2R8YFS5_HUMAN,tr|A0A0D9SF53|A0A0D9SF53_HUMAN,tr|A0A2R8Y650|A0A2R8Y650_HUMAN,tr|A0A087WX09|A0A087WX09_HUMAN,tr|C9J081|C9J081_HUMAN,tr|A0A2R8Y5G6|A0A2R8Y5G6_HUMAN,tr|A0A0D9SG12|A0A0D9SG12_HUMAN,tr|F6S8Q4|F6S8Q4_HUMAN,tr|A0A2U3TZJ9|A0A2U3TZJ9_HUMAN,tr|A0A2R8Y4A4|A0A2R8Y4A4_HUMAN,tr|A0A2R8YF89|A0A2R8YF89_HUMAN" 21 1231.5469 0.98 97687 9694 3 1231.546279 411.5229 ATP-dependent RNA helicase DDX3X OS=Homo sapiens OX=9606 GN=DDX3X PE=1 SV=3 5.96 1997.3 - 2.63E+06 - - - -0.5286 - 2.047 0.535 - 216.2 1 2 1 -0.0007 11 0 0 0 1.38E+08 1.40E+08 - - - 6.5396 0.9971 221125_WJC_METTL3_EV_vs_WT_F07.09696.09696.2 0.368 20-Sep K.DK[136.11]DAYSSFGSR[166.11].S "sp|O00571|DDX3X_HUMAN,sp|O15523|DDX3Y_HUMAN,tr|A0A2R8YFR4|A0A2R8YFR4_HUMAN,tr|A0A2R8YCW1|A0A2R8YCW1_HUMAN,tr|A0A2R8YDH3|A0A2R8YDH3_HUMAN,tr|A0A2R8Y645|A0A2R8Y645_HUMAN,tr|A0A2R8YF78|A0A2R8YF78_HUMAN,tr|C9J8G5|C9J8G5_HUMAN,tr|A0A2R8YCU0|A0A2R8YCU0_HUMAN,tr|A0A0D9SFB3|A0A0D9SFB3_HUMAN,tr|A0A2R8YFS5|A0A2R8YFS5_HUMAN,tr|A0A0D9SF53|A0A0D9SF53_HUMAN,tr|A0A2R8Y650|A0A2R8Y650_HUMAN,tr|A0A087WX09|A0A087WX09_HUMAN,tr|C9J081|C9J081_HUMAN,tr|A0A2R8Y5G6|A0A2R8Y5G6_HUMAN,tr|A0A0D9SG12|A0A0D9SG12_HUMAN,tr|F6S8Q4|F6S8Q4_HUMAN,tr|A0A2U3TZJ9|A0A2U3TZJ9_HUMAN,tr|A0A2R8Y4A4|A0A2R8Y4A4_HUMAN,tr|A0A2R8YF89|A0A2R8YF89_HUMAN" 21 1249.5694 1.05 97689 9696 2 1249.569793 625.792 ATP-dependent RNA helicase DDX3X OS=Homo sapiens OX=9606 GN=DDX3X PE=1 SV=3 5.96 1997.5 - 919927 - - - 0.3145 - 2.058 0.377 - 266.8 1 2 1 0.0004 11 0 0 0 5.12E+07 4.87E+07 - - - 3.7779 0.9993 221125_WJC_METTL3_EV_vs_WT_F07.09697.09697.2 0.0423 14-Sep K.VGEVIVTK.D "sp|P10809|CH60_HUMAN,tr|A0A7I2V2X6|A0A7I2V2X6_HUMAN,tr|A0A7I2YQK6|A0A7I2YQK6_HUMAN,tr|A0A7I2V599|A0A7I2V599_HUMAN" 4 843.5066 1.24 97690 9697 2 843.504797 422.7606 "60 kDa heat shock protein, mitochondrial OS=Homo sapiens OX=9606 GN=HSPD1 PE=1 SV=2" 5.97 1997.6 - 785629 - - - -2.1008 - 1.957 0.33 - 209.6 1 2 0 -0.0018 8 0 0 0 1.19E+07 9.67E+06 - - - 3.5028 0.9947 221125_WJC_METTL3_EV_vs_WT_F07.09706.09706.2 2.86E-05 13/20 K.DKDAYSSFGSR.S "sp|O00571|DDX3X_HUMAN,sp|O15523|DDX3Y_HUMAN,tr|A0A2R8YFR4|A0A2R8YFR4_HUMAN,tr|A0A2R8YCW1|A0A2R8YCW1_HUMAN,tr|A0A2R8YDH3|A0A2R8YDH3_HUMAN,tr|A0A2R8Y645|A0A2R8Y645_HUMAN,tr|A0A2R8YF78|A0A2R8YF78_HUMAN,tr|C9J8G5|C9J8G5_HUMAN,tr|A0A2R8YCU0|A0A2R8YCU0_HUMAN,tr|A0A0D9SFB3|A0A0D9SFB3_HUMAN,tr|A0A2R8YFS5|A0A2R8YFS5_HUMAN,tr|A0A0D9SF53|A0A0D9SF53_HUMAN,tr|A0A2R8Y650|A0A2R8Y650_HUMAN,tr|A0A087WX09|A0A087WX09_HUMAN,tr|C9J081|C9J081_HUMAN,tr|A0A2R8Y5G6|A0A2R8Y5G6_HUMAN,tr|A0A0D9SG12|A0A0D9SG12_HUMAN,tr|F6S8Q4|F6S8Q4_HUMAN,tr|A0A2U3TZJ9|A0A2U3TZJ9_HUMAN,tr|A0A2R8Y4A4|A0A2R8Y4A4_HUMAN,tr|A0A2R8YF89|A0A2R8YF89_HUMAN" 21 1231.5469 1.05 97697 9706 2 1231.543445 616.7807 ATP-dependent RNA helicase DDX3X OS=Homo sapiens OX=9606 GN=DDX3X PE=1 SV=3 5.96 1998.6 - 1.18E+06 - - - -2.8298 - 2.346 0.477 - 618 1 2 1 -0.0035 11 0 0 0 5.12E+07 4.87E+07 - - - 4.8698 0.9993 221125_WJC_METTL3_EV_vs_WT_F07.09707.09707.3 0.000604 Nov-40 K.TK[136.11]EGVLYVGSK[136.11].T "sp|Q16143|SYUB_HUMAN,sp|P37840|SYUA_HUMAN,tr|A0A669KB41|A0A669KB41_HUMAN,tr|D6RA31|D6RA31_HUMAN,tr|A0A669KBH5|A0A669KBH5_HUMAN,tr|E7EPV7|E7EPV7_HUMAN" 6 1195.6783 1.28 97698 9707 3 1195.67693 399.5667 Beta-synuclein OS=Homo sapiens OX=9606 GN=SNCB PE=1 SV=1 8.17 1998.7 - 735084 - - - -1.1784 - 2.167 0.376 - 150.3 1 2 1 -0.0014 11 0 0 0 2.11E+07 1.64E+07 - - - 4.9286 0.9996 221125_WJC_METTL3_EV_vs_WT_F07.09710.09710.3 0.000264 15/48 K.VTNSTELQHQLDK[136.11].T sp|Q15075|EEA1_HUMAN 1 1519.7722 1.24 97699 9710 3 1519.770297 507.598 Early endosome antigen 1 OS=Homo sapiens OX=9606 GN=EEA1 PE=1 SV=2 5.32 1999.1 - 575588 - - - -1.2429 - 2.562 0.264 - 286 1 2 0 -0.0019 13 0 0 0 1.13E+07 9.13E+06 - - - 4.0336 0.9999 221125_WJC_METTL3_EV_vs_WT_F07.09712.09712.2 0.000813 13/28 K.QGGGGGGGSVPGIER.M "sp|P52272|HNRPM_HUMAN,tr|M0R019|M0R019_HUMAN,tr|A0A087X0X3|A0A087X0X3_HUMAN,tr|M0R2T0|M0R2T0_HUMAN" 4 1283.6218 1.69 97700 9712 2 1283.620474 642.8182 Heterogeneous nuclear ribonucleoprotein M OS=Homo sapiens OX=9606 GN=HNRNPM PE=1 SV=3 6 1999.3 - 3.85E+07 - - - -1.054 - 2.546 0.529 - 343.2 1 2 0 -0.0014 15 0 0 0 1.90E+09 1.13E+09 - - - 5.2453 0.9401 221125_WJC_METTL3_EV_vs_WT_F07.09716.09716.2 0.0223 12-Jul G.PTLSYGR[166.11].D "sp|P43243|MATR3_HUMAN,tr|A8MXP9|A8MXP9_HUMAN,tr|D6R991|D6R991_HUMAN,tr|A0A0R4J2E8|A0A0R4J2E8_HUMAN,tr|D6REM6|D6REM6_HUMAN" 5 802.4213 0.94 97703 9716 2 802.420763 402.2179 Matrin-3 OS=Homo sapiens OX=9606 GN=MATR3 PE=1 SV=2 9.18 1999.8 - 785625 - - - -0.6356 - 1.451 0.291 - 153.8 1 1 0 -0.0005 7 0 0 0 2.35E+07 2.49E+07 - - - 2.3697 0.9999 221125_WJC_METTL3_EV_vs_WT_F07.09725.09725.2 3.32E-05 13/22 R.SQEDEISSPVNK.V "sp|Q5UIP0|RIF1_HUMAN,tr|H7C2B5|H7C2B5_HUMAN" 2 1331.6205 1.34 97710 9725 2 1331.619044 666.8175 Telomere-associated protein RIF1 OS=Homo sapiens OX=9606 GN=RIF1 PE=1 SV=2 4.14 2001 - 828293 - - - -1.0851 - 2.625 0.56 - 672.7 1 2 0 -0.0014 12 0 0 0 2.60E+07 1.94E+07 - - - 5.716 0.9999 221125_WJC_METTL3_EV_vs_WT_F07.09727.09727.3 0.00136 Dec-48 K.VTNSTELQHQLDK.T sp|Q15075|EEA1_HUMAN 1 1511.758 1.17 97712 9727 3 1511.757718 504.9266 Early endosome antigen 1 OS=Homo sapiens OX=9606 GN=EEA1 PE=1 SV=2 5.32 2001.2 - 744073 - - - -0.1773 - 2.489 0.36 - 157.3 1 2 0 -0.0003 13 0 0 0 1.14E+07 9.77E+06 - - - 5.0259 0.9999 221125_WJC_METTL3_EV_vs_WT_F07.09729.09729.3 7.03E-05 13/36 R.NGVMPSHFSR[166.11].G "sp|P39019|RS19_HUMAN,tr|A0A075B6E2|A0A075B6E2_HUMAN" 2 1140.5374 0.001 97714 9729 3 1140.539344 381.1864 40S ribosomal protein S19 OS=Homo sapiens OX=9606 GN=RPS19 PE=1 SV=2 9.76 2001.4 - 609919 - - - 1.7202 - 2.375 0.381 - 441.1 1 2 0 0.002 10 0 0 0 0.00E+00 2.35E+07 - - - 5.3134 1 221125_WJC_METTL3_EV_vs_WT_F07.09733.09733.3 0.00112 Nov-40 R.NTFDHPYPTTK.L sp|P61962|DCAF7_HUMAN 1 1319.6146 1.36 97716 9733 3 1319.615569 440.8788 DDB1- and CUL4-associated factor 7 OS=Homo sapiens OX=9606 GN=DCAF7 PE=1 SV=1 6.74 2001.9 - 2.68E+06 - - - 0.7222 - 2.214 0.46 - 193.6 1 2 0 0.001 11 0 0 0 3.11E+07 2.28E+07 - - - 5.9262 0.9998 221125_WJC_METTL3_EV_vs_WT_F07.09734.09734.3 0.00115 Dec-40 R.NTFDHPYPTTK[136.11].L sp|P61962|DCAF7_HUMAN 1 1327.6288 1.36 97717 9734 3 1327.629547 443.5502 DDB1- and CUL4-associated factor 7 OS=Homo sapiens OX=9606 GN=DCAF7 PE=1 SV=1 6.74 2001.9 - 2.51E+06 - - - 0.5506 - 1.752 0.381 - 228.6 1 2 0 0.0007 11 0 0 0 3.11E+07 2.28E+07 - - - 4.3806 0.9777 221125_WJC_METTL3_EV_vs_WT_F07.09738.09738.2 0.000144 20-Oct K.TK[136.11]EGVLYVGSK[136.11].T "sp|Q16143|SYUB_HUMAN,sp|P37840|SYUA_HUMAN,tr|A0A669KB41|A0A669KB41_HUMAN,tr|D6RA31|D6RA31_HUMAN,tr|A0A669KBH5|A0A669KBH5_HUMAN,tr|E7EPV7|E7EPV7_HUMAN" 6 1195.6783 3.54 97721 9738 2 1195.682972 598.8464 Beta-synuclein OS=Homo sapiens OX=9606 GN=SNCB PE=1 SV=1 8.17 2002.4 - 341980 - - - 3.8748 - 1.8 0.44 - 231.9 1 2 1 0.0046 11 0 0 0 6.99E+06 1.97E+06 - - - 3.8795 1 221125_WJC_METTL3_EV_vs_WT_F07.09740.09740.3 0.0281 14/44 R.R[166.11]TEEGPTLSYGR[166.11].D "sp|P43243|MATR3_HUMAN,tr|A8MXP9|A8MXP9_HUMAN,tr|D6R991|D6R991_HUMAN,tr|A0A0R4J2E8|A0A0R4J2E8_HUMAN,tr|D6REM6|D6REM6_HUMAN" 5 1384.685 1.35 97722 9740 3 1384.684134 462.5689 Matrin-3 OS=Homo sapiens OX=9606 GN=MATR3 PE=1 SV=2 6.14 2002.7 - 5.31E+07 - - - -0.6124 - 2.767 0.417 - 337.8 1 2 0 -0.0008 12 0 0 0 5.13E+09 3.82E+09 - - - 6.01 1 221125_WJC_METTL3_EV_vs_WT_F07.09743.09743.2 2.88E-10 19/28 R.SFGGGC[160.03]HVTAAVSSR[166.11].R "sp|Q9NRA8|4ET_HUMAN,tr|B1AKL5|B1AKL5_HUMAN,tr|B1AKL4|B1AKL4_HUMAN" 3 1501.6971 0.96 97724 9743 2 1501.696874 751.8558 Eukaryotic translation initiation factor 4E transporter OS=Homo sapiens OX=9606 GN=EIF4ENIF1 PE=1 SV=2 7.99 2003 - 769180 - - - -0.1711 - 3.285 0.681 - 1099.9 1 2 0 -0.0003 15 0 0 0 1.71E+07 1.79E+07 - - - 6.9949 0.9999 221125_WJC_METTL3_EV_vs_WT_F07.09744.09744.3 3.14E-07 17/64 K.GAVAEDGDELR[166.11]TEPEAK[136.11].K "sp|P27695|APEX1_HUMAN,tr|G3V3C7|G3V3C7_HUMAN,tr|G3V5D9|G3V5D9_HUMAN,tr|G3V3M6|G3V3M6_HUMAN,tr|A0A0C4DGK8|A0A0C4DGK8_HUMAN,tr|G3V5Q1|G3V5Q1_HUMAN" 6 1803.8606 0.2 97725 9744 3 1803.85846 602.2941 DNA-(apurinic or apyrimidinic site) endonuclease OS=Homo sapiens OX=9606 GN=APEX1 PE=1 SV=2 4.08 2003.1 - 1.86E+06 - - - -1.1625 - 3.12 0.589 - 399.2 1 2 1 -0.0021 17 0 0 0 5.32E+06 2.67E+07 - - - 7.9807 0.9986 221125_WJC_METTL3_EV_vs_WT_F07.09745.09745.3 0.0115 Dec-40 K.TKEGVLYVGSK.T "sp|Q16143|SYUB_HUMAN,sp|P37840|SYUA_HUMAN,tr|A0A669KB41|A0A669KB41_HUMAN,tr|D6RA31|D6RA31_HUMAN,tr|A0A669KBH5|A0A669KBH5_HUMAN,tr|E7EPV7|E7EPV7_HUMAN" 6 1179.6499 1.29 97726 9745 3 1179.648283 394.2239 Beta-synuclein OS=Homo sapiens OX=9606 GN=SNCB PE=1 SV=1 8.17 2003.2 - 1.09E+06 - - - -1.4038 - 1.836 0.371 - 166.5 1 2 1 -0.0017 11 0 0 0 2.12E+07 1.64E+07 - - - 4.4019 0.9985 221125_WJC_METTL3_EV_vs_WT_F07.09746.09746.3 0.0122 Nov-56 K.QGGGGGGGSVPGIER[166.11].M "sp|P52272|HNRPM_HUMAN,tr|M0R019|M0R019_HUMAN,tr|A0A087X0X3|A0A087X0X3_HUMAN,tr|M0R2T0|M0R2T0_HUMAN" 4 1293.6301 1.75 97727 9746 3 1293.628876 432.2173 Heterogeneous nuclear ribonucleoprotein M OS=Homo sapiens OX=9606 GN=HNRNPM PE=1 SV=3 6 2003.3 - 845466 - - - -0.9439 - 1.488 0.308 - 113.3 1 2 0 -0.0012 15 0 0 0 2.66E+07 1.52E+07 - - - 3.0106 0.9993 221125_WJC_METTL3_EV_vs_WT_F07.09747.09747.2 0.000488 20-Sep R.NNNQQLAQLQK[136.11].E sp|Q9Y2A7|NCKP1_HUMAN 1 1305.6881 0.001 97728 9747 2 1305.685071 653.8513 Nck-associated protein 1 OS=Homo sapiens OX=9606 GN=NCKAP1 PE=1 SV=1 8.75 2003.4 - 439093 - - - -2.2907 - 1.93 0.393 - 310.7 1 2 0 -0.003 11 0 0 0 0.00E+00 4.27E+06 - - - 3.7215 0.9996 221125_WJC_METTL3_EV_vs_WT_F07.09748.09748.3 0.00221 13/52 K.DGGAQHAQYVGPYR[166.11].L sp|Q8IWQ3|BRSK2_HUMAN 1 1527.7094 2.56 97729 9748 3 1527.706065 510.2437 Serine\threonine-protein kinase BRSK2 OS=Homo sapiens OX=9606 GN=BRSK2 PE=1 SV=3 6.74 2003.6 - 438849 - - - -2.1896 - 1.896 0.388 - 134.9 1 2 0 -0.0033 14 0 0 0 2.10E+07 8.20E+06 - - - 4.565 0.9999 221125_WJC_METTL3_EV_vs_WT_F07.09749.09749.2 3.02E-06 20-Oct R.NTFDHPYPTTK.L sp|P61962|DCAF7_HUMAN 1 1319.6146 1.29 97730 9749 2 1319.615422 660.8146 DDB1- and CUL4-associated factor 7 OS=Homo sapiens OX=9606 GN=DCAF7 PE=1 SV=1 6.74 2003.7 - 294765 - - - 0.6108 - 2.036 0.567 - 249.6 1 2 0 0.0008 11 0 0 0 3.30E+06 2.55E+06 - - - 5.152 0.9998 221125_WJC_METTL3_EV_vs_WT_F07.09753.09753.2 0.000219 16/20 R.KGLSEDVSISK.F "sp|Q15029|U5S1_HUMAN,tr|K7EP67|K7EP67_HUMAN" 2 1161.6241 1.39 97732 9753 2 1161.621958 581.8193 116 kDa U5 small nuclear ribonucleoprotein component OS=Homo sapiens OX=9606 GN=EFTUD2 PE=1 SV=1 6.07 2004.2 - 846276 - - - -1.8595 - 2.656 0.481 - 309.3 1 2 0 -0.0022 11 0 0 0 9.40E+06 6.79E+06 - - - 5.2355 1 221125_WJC_METTL3_EV_vs_WT_F07.09755.09755.3 0.000154 Dec-40 R.HVGSNLC[160.03]LDSR[166.11].T sp|Q10471|GALT2_HUMAN 1 1266.6014 3.29 97734 9755 3 1266.600226 423.2078 Polypeptide N-acetylgalactosaminyltransferase 2 OS=Homo sapiens OX=9606 GN=GALNT2 PE=1 SV=1 6.74 2004.4 - 1.05E+06 - - - -0.9577 - 2.216 0.459 - 261.9 1 2 0 -0.0012 11 0 0 0 4.44E+07 1.35E+07 - - - 5.9175 0.9938 221125_WJC_METTL3_EV_vs_WT_F07.09756.09756.3 0.161 Oct-32 R.TSYEEFTHK[136.11].D sp|Q6P2Q9|PRP8_HUMAN 1 1148.523 1.6 97735 9756 3 1148.522351 383.8483 Pre-mRNA-processing-splicing factor 8 OS=Homo sapiens OX=9606 GN=PRPF8 PE=1 SV=2 5.37 2004.5 - 732288 - - - -0.525 - 1.63 0.187 - 147.9 1 2 0 -0.0006 9 0 0 0 1.11E+07 6.91E+06 - - - 2.0972 0.8967 221125_WJC_METTL3_EV_vs_WT_F07.09757.09757.3 0.00447 Nov-48 Q.LDDPSC[160.03]PR[166.11]PEC[160.03]YR[166.11].S "sp|Q2VIR3|IF2GL_HUMAN,sp|P41091|IF2G_HUMAN,tr|H7BZU1|H7BZU1_HUMAN" 3 1683.7248 0.96 97736 9757 3 1683.723799 562.2489 Eukaryotic translation initiation factor 2 subunit 3B OS=Homo sapiens OX=9606 GN=EIF2S3B PE=2 SV=2 4.56 2004.7 - 652472 - - - -0.604 - 1.687 0.295 - 85.3 1 1 0 -0.001 13 0 0 0 6.20E+07 6.45E+07 - - - 3.2466 0.9997 221125_WJC_METTL3_EV_vs_WT_F07.09758.09758.2 4.32E-05 13/20 R.HVGSNLC[160.03]LDSR[166.11].T sp|Q10471|GALT2_HUMAN 1 1266.6014 2.06 97737 9758 2 1266.59976 634.308 Polypeptide N-acetylgalactosaminyltransferase 2 OS=Homo sapiens OX=9606 GN=GALNT2 PE=1 SV=1 6.74 2004.8 - 643851 - - - -1.3256 - 1.863 0.428 - 441.1 1 2 0 -0.0017 11 0 0 0 2.94E+07 1.43E+07 - - - 3.8848 0.9999 221125_WJC_METTL3_EV_vs_WT_F07.09759.09759.3 1.50E-05 14/40 R.KGLSEDVSISK.F "sp|Q15029|U5S1_HUMAN,tr|K7EP67|K7EP67_HUMAN" 2 1161.6241 0.41 97738 9759 3 1161.620576 388.2153 116 kDa U5 small nuclear ribonucleoprotein component OS=Homo sapiens OX=9606 GN=EFTUD2 PE=1 SV=1 6.07 2004.9 - 542913 - - - -3.0492 - 2.598 0.463 - 272 1 2 0 -0.0035 11 0 0 0 7.23E+06 1.76E+07 - - - 6.4133 1 221125_WJC_METTL3_EV_vs_WT_F07.09760.09760.2 6.65E-07 24-Sep R.EEQNGEDEDGGWR.L "sp|Q6Y7W6|GGYF2_HUMAN,tr|I1E4Y6|I1E4Y6_HUMAN,tr|A0A7I2V516|A0A7I2V516_HUMAN,tr|A0A7I2V3H0|A0A7I2V3H0_HUMAN,tr|C9JHW1|C9JHW1_HUMAN,tr|E7ESB6|E7ESB6_HUMAN" 6 1519.5811 11.23 97739 9760 2 1519.582832 760.7978 GRB10-interacting GYF protein 2 OS=Homo sapiens OX=9606 GN=GIGYF2 PE=1 SV=1 3.77 2005 - 436819 - - - 1.1108 - 1.991 0.699 - 264.8 1 2 0 0.0017 13 0 0 0 5.23E+06 4.66E+05 - - - 5.9707 0.9985 221125_WJC_METTL3_EV_vs_WT_F07.09761.09761.3 0.149 Sep-44 R.SDKPGVYTNIC[160.03]R.Y "sp|O60259|KLK8_HUMAN,tr|A0A0A0MQY9|A0A0A0MQY9_HUMAN" 2 1408.6769 9.78 97740 9761 3 1408.677304 470.5662 Kallikrein-8 OS=Homo sapiens OX=9606 GN=KLK8 PE=1 SV=1 7.92 2005.1 - 424571 - - - 0.2875 - 1.836 0.251 - 92 1 2 0 0.0004 12 0 0 0 3.44E+06 3.52E+05 - - - 3.0224 0.9992 221125_WJC_METTL3_EV_vs_WT_F07.09763.09763.2 0.00283 26-Jun R.GGGGGPC[160.03]GFQPASR[166.11].G sp|Q96QR8|PURB_HUMAN 1 1313.581 3.8 97742 9763 2 1313.57991 657.7978 Transcriptional activator protein Pur-beta OS=Homo sapiens OX=9606 GN=PURB PE=1 SV=3 8.25 2005.4 - 172384 - - - -0.8587 - 1.386 0.375 - 82.9 1 2 0 -0.0011 14 0 0 0 3.05E+06 8.02E+05 - - - 2.6295 1 221125_WJC_METTL3_EV_vs_WT_F07.09766.09766.3 1.04E-05 13/44 R.RTEEGPTLSYGR.D "sp|P43243|MATR3_HUMAN,tr|A8MXP9|A8MXP9_HUMAN,tr|D6R991|D6R991_HUMAN,tr|A0A0R4J2E8|A0A0R4J2E8_HUMAN,tr|D6REM6|D6REM6_HUMAN" 5 1364.6684 1.35 97743 9766 3 1364.667833 455.8968 Matrin-3 OS=Homo sapiens OX=9606 GN=MATR3 PE=1 SV=2 6.14 2005.8 - 1.13E+07 - - - -0.4463 - 2.461 0.514 - 269.8 1 2 0 -0.0006 12 0 0 0 5.14E+09 3.82E+09 - - - 6.7667 0.9811 221125_WJC_METTL3_EV_vs_WT_F07.09770.09770.3 0.0108 13/48 Q.LDDPSC[160.03]PRPEC[160.03]YR.S "sp|Q2VIR3|IF2GL_HUMAN,sp|P41091|IF2G_HUMAN,tr|H7BZU1|H7BZU1_HUMAN" 3 1663.7083 0.96 97747 9770 3 1663.706251 555.5767 Eukaryotic translation initiation factor 2 subunit 3B OS=Homo sapiens OX=9606 GN=EIF2S3B PE=2 SV=2 4.56 2006.1 - 1.30E+06 - - - -1.2172 - 2.008 0.386 - 172.7 1 1 0 -0.002 13 0 0 0 6.20E+07 6.45E+07 - - - 4.7331 0.9999 221125_WJC_METTL3_EV_vs_WT_F07.09771.09771.3 0.000579 13/48 K.KAISSTEAVLNNR.F "sp|Q5T8P6|RBM26_HUMAN,sp|Q9P2N5|RBM27_HUMAN,tr|U3KPZ7|U3KPZ7_HUMAN,tr|A0A087X0H9|A0A087X0H9_HUMAN" 4 1401.7576 0.27 97748 9771 3 1401.757948 468.2598 RNA-binding protein 26 OS=Homo sapiens OX=9606 GN=RBM26 PE=1 SV=3 8.75 2006.2 - 1.11E+06 - - - 0.254 - 2.431 0.418 - 294.2 1 2 0 0.0004 13 0 0 0 1.33E+07 4.90E+07 - - - 5.6086 1 221125_WJC_METTL3_EV_vs_WT_F07.09774.09774.3 5.68E-08 19/60 R.VDEEPTTLPSGEAKPR.K "sp|Q641Q2|WAC2A_HUMAN,sp|Q9Y4E1|WAC2C_HUMAN,tr|F8W7U3|F8W7U3_HUMAN,tr|J3KP36|J3KP36_HUMAN,tr|E7ESD2|E7ESD2_HUMAN,tr|A0A0A0MT65|A0A0A0MT65_HUMAN,tr|A0A0A0MR88|A0A0A0MR88_HUMAN,tr|A0A096LPC5|A0A096LPC5_HUMAN" 8 1724.8581 2.64 97751 9774 3 1724.86 575.96 WASH complex subunit 2A OS=Homo sapiens OX=9606 GN=WASHC2A PE=1 SV=3 4.41 2006.5 - 772421 - - - 1.105 - 3.592 0.535 - 383.7 1 2 0 0.0019 16 0 0 0 4.17E+06 1.58E+06 - - - 7.7852 0.9999 221125_WJC_METTL3_EV_vs_WT_F07.09775.09775.3 0.00149 20/56 K.ALAAAGYDVEK[136.11]NNSR[166.11].L "sp|P10412|H14_HUMAN,sp|Q02539|H11_HUMAN,sp|P22492|H1T_HUMAN,sp|P16403|H12_HUMAN,sp|P16402|H13_HUMAN" 5 1595.8023 0.78 97752 9775 3 1595.800884 532.9414 Histone H1.4 OS=Homo sapiens OX=9606 GN=H1-4 PE=1 SV=2 6.11 2006.6 - 664620 - - - -0.8585 - 3.633 0.472 - 587.2 1 2 1 -0.0014 15 0 0 0 8.11E+06 1.05E+07 - - - 7.1682 0.9999 221125_WJC_METTL3_EV_vs_WT_F07.09777.09777.3 4.25E-06 24/56 K.ALAAAGYDVEKNNSR.L "sp|P10412|H14_HUMAN,sp|Q02539|H11_HUMAN,sp|P22492|H1T_HUMAN,sp|P16403|H12_HUMAN,sp|P16402|H13_HUMAN" 5 1577.7798 0.78 97754 9777 3 1577.778387 526.9339 Histone H1.4 OS=Homo sapiens OX=9606 GN=H1-4 PE=1 SV=2 6.11 2006.9 - 538802 - - - -0.8854 - 3.946 0.524 - 925.3 1 2 1 -0.0014 15 0 0 0 8.11E+06 1.05E+07 - - - 7.9636 1 221125_WJC_METTL3_EV_vs_WT_F07.09784.09784.2 2.42E-05 13/34 R.AGGPPQVAGAQAAC[160.03]SEDR.M "sp|Q9H3R5|CENPH_HUMAN,tr|B3KVZ3|B3KVZ3_HUMAN,tr|D6RBJ6|D6RBJ6_HUMAN" 3 1740.7849 0.38 97761 9784 2 1740.784049 871.3997 Centromere protein H OS=Homo sapiens OX=9606 GN=CENPH PE=1 SV=1 4.37 2007.7 - 196896 - - - -0.5153 - 2.957 0.677 - 392.8 1 2 0 -0.0009 18 0 0 0 7.80E+06 2.07E+07 - - - 6.7065 0.9999 221125_WJC_METTL3_EV_vs_WT_F07.09790.09790.3 0.000899 Dec-48 K.K[136.11]AISSTEAVLNNR[166.11].F "sp|Q5T8P6|RBM26_HUMAN,sp|Q9P2N5|RBM27_HUMAN,tr|U3KPZ7|U3KPZ7_HUMAN,tr|A0A087X0H9|A0A087X0H9_HUMAN" 4 1419.7801 0.24 97765 9790 3 1419.779877 474.2673 RNA-binding protein 26 OS=Homo sapiens OX=9606 GN=RBM26 PE=1 SV=3 8.75 2008.4 - 1.58E+06 - - - -0.1303 - 2.369 0.403 - 237.2 1 2 0 -0.0002 13 0 0 0 1.44E+07 5.93E+07 - - - 5.3714 1 221125_WJC_METTL3_EV_vs_WT_F07.09791.09791.3 1.11E-05 13/56 R.ETPHSPGVEDAPIAK.V "sp|Q9UHB6|LIMA1_HUMAN,tr|F8VQE1|F8VQE1_HUMAN,tr|F8VS07|F8VS07_HUMAN" 3 1546.7627 1.64 97766 9791 3 1546.763 516.5949 LIM domain and actin-binding protein 1 OS=Homo sapiens OX=9606 GN=LIMA1 PE=1 SV=1 4.65 2008.5 - 884641 - - - 0.17 - 2.119 0.506 - 207.6 1 2 0 0.0003 15 0 0 0 2.83E+07 1.73E+07 - - - 6.1408 0.9999 221125_WJC_METTL3_EV_vs_WT_F07.09792.09792.3 2.22E-05 14/44 K.NC[160.03]PHIVVGTPGR[166.11].L "sp|Q13838|DX39B_HUMAN,tr|A0A140TA18|A0A140TA18_HUMAN,tr|F6UJC5|F6UJC5_HUMAN,tr|F6TRA5|F6TRA5_HUMAN,tr|F6WLT2|F6WLT2_HUMAN,tr|Q5STU3|Q5STU3_HUMAN,tr|A0A140T973|A0A140T973_HUMAN,tr|A0A140T9X9|A0A140T9X9_HUMAN,tr|A0A140T996|A0A140T996_HUMAN,tr|A0A140T9L4|A0A140T9L4_HUMAN,tr|A0A0G2JJZ9|A0A0G2JJZ9_HUMAN,tr|A0A140T9K1|A0A140T9K1_HUMAN,tr|A0A140T9X3|A0A140T9X3_HUMAN,tr|F6S4E6|F6S4E6_HUMAN,tr|A0A0A0MT12|A0A0A0MT12_HUMAN" 15 1315.6695 1.08 97767 9792 3 1315.669901 439.5638 Spliceosome RNA helicase DDX39B OS=Homo sapiens OX=9606 GN=DDX39B PE=1 SV=1 8.26 2008.6 - 789696 - - - 0.336 - 2.649 0.389 - 361 1 2 0 0.0004 12 0 0 0 1.57E+07 1.46E+07 - - - 5.5771 0.9999 221125_WJC_METTL3_EV_vs_WT_F07.09793.09793.3 0.00175 Oct-44 K.NC[160.03]PHIVVGTPGR.L "sp|Q13838|DX39B_HUMAN,tr|A0A140TA18|A0A140TA18_HUMAN,tr|F6UJC5|F6UJC5_HUMAN,tr|F6TRA5|F6TRA5_HUMAN,tr|F6WLT2|F6WLT2_HUMAN,tr|Q5STU3|Q5STU3_HUMAN,tr|A0A140T973|A0A140T973_HUMAN,tr|A0A140T9X9|A0A140T9X9_HUMAN,tr|A0A140T996|A0A140T996_HUMAN,tr|A0A140T9L4|A0A140T9L4_HUMAN,tr|A0A0G2JJZ9|A0A0G2JJZ9_HUMAN,tr|A0A140T9K1|A0A140T9K1_HUMAN,tr|A0A140T9X3|A0A140T9X3_HUMAN,tr|F6S4E6|F6S4E6_HUMAN,tr|A0A0A0MT12|A0A0A0MT12_HUMAN" 15 1305.6612 1.08 97768 9793 3 1305.662144 436.2277 Spliceosome RNA helicase DDX39B OS=Homo sapiens OX=9606 GN=DDX39B PE=1 SV=1 8.26 2008.7 - 617757 - - - 0.7314 - 2.107 0.4 - 189.8 1 2 0 0.001 12 0 0 0 1.57E+07 1.46E+07 - - - 5.0651 0.9999 221125_WJC_METTL3_EV_vs_WT_F07.09794.09794.3 2.26E-06 15/52 R.DTPGHGSGWAETPR.T sp|O75533|SF3B1_HUMAN 1 1466.6539 1.14 97769 9794 3 1466.649092 489.8919 Splicing factor 3B subunit 1 OS=Homo sapiens OX=9606 GN=SF3B1 PE=1 SV=3 5.32 2008.8 - 582010 - - - -3.2475 - 2.514 0.527 - 305.7 1 2 0 -0.0048 14 0 0 0 4.30E+07 3.79E+07 - - - 6.8641 0.9997 221125_WJC_METTL3_EV_vs_WT_F07.09795.09795.3 0.00183 Dec-44 R.FEEEIKAEQEER.K sp|Q96C19|EFHD2_HUMAN 1 1535.7104 1.89 97770 9795 3 1535.710497 512.9107 EF-hand domain-containing protein D2 OS=Homo sapiens OX=9606 GN=EFHD2 PE=1 SV=1 4.21 2008.9 - 556483 - - - 0.0847 - 2.397 0.427 - 145.3 1 2 1 0.0001 12 0 0 0 9.49E+06 5.03E+06 - - - 5.7238 1 221125_WJC_METTL3_EV_vs_WT_F07.09796.09796.2 0.0055 13/24 K.KAISSTEAVLNNR.F "sp|Q5T8P6|RBM26_HUMAN,sp|Q9P2N5|RBM27_HUMAN,tr|U3KPZ7|U3KPZ7_HUMAN,tr|A0A087X0H9|A0A087X0H9_HUMAN" 4 1401.7576 0.62 97771 9796 2 1401.756593 701.8861 RNA-binding protein 26 OS=Homo sapiens OX=9606 GN=RBM26 PE=1 SV=3 8.75 2009 - 427628 - - - -0.7127 - 2.913 0.542 - 572.7 1 2 0 -0.001 13 0 0 0 1.86E+06 3.02E+06 - - - 5.788 0.9995 221125_WJC_METTL3_EV_vs_WT_F07.09798.09798.3 0.000972 Nov-40 R.R[166.11]GGPISFSSSR[166.11].S sp|P35580|MYH10_HUMAN 1 1169.6056 0.82 97773 9798 3 1169.609589 390.8758 Myosin-10 OS=Homo sapiens OX=9606 GN=MYH10 PE=1 SV=3 12 2009.2 - 232400 - - - 3.402 - 1.917 0.427 - 188 1 2 0 0.004 11 0 0 0 1.47E+07 1.79E+07 - - - 5.1482 0.9832 221125_WJC_METTL3_EV_vs_WT_F07.09799.09799.2 0.00502 20-Jul K.SKWEMDTSEAK.L "sp|P49750|YLPM1_HUMAN,tr|F8VU51|F8VU51_HUMAN" 2 1310.5813 -1 97774 9799 2 1310.582631 656.2979 YLP motif-containing protein 1 OS=Homo sapiens OX=9606 GN=YLPM1 PE=1 SV=4 4.68 2009.4 - 153462 - - - 1.0408 - 1.392 0.315 - 93.9 1 2 1 0.0014 11 0 0 0 0.00E+00 0.00E+00 - - - 2.2619 0.9998 221125_WJC_METTL3_EV_vs_WT_F07.09801.09801.2 0.000709 28-Nov K.GSC[160.03]GIGGGIGGGSSR.L "sp|P02533|K1C14_HUMAN,sp|P08779|K1C16_HUMAN,tr|K7ENV3|K7ENV3_HUMAN" 3 1277.5782 999 97775 9801 2 1277.576032 639.7964 "Keratin, type I cytoskeletal 14 OS=Homo sapiens OX=9606 GN=KRT14 PE=1 SV=4" 8.25 2009.6 - 582649 - - - -1.7337 - 2.122 0.533 - 241.9 1 2 0 -0.0022 15 0 0 0 7.61E+06 0.00E+00 - - - 4.8268 0.9999 221125_WJC_METTL3_EV_vs_WT_F07.09805.09805.3 3.84E-05 Nov-52 R.DTPGHGSGWAETPR[166.11].T sp|O75533|SF3B1_HUMAN 1 1476.6621 1.14 97779 9805 3 1476.665174 493.228 Splicing factor 3B subunit 1 OS=Homo sapiens OX=9606 GN=SF3B1 PE=1 SV=3 5.32 2009.9 - 1.42E+06 - - - 2.0648 - 2.554 0.473 - 156.3 1 2 0 0.003 14 0 0 0 4.30E+07 3.79E+07 - - - 6.3045 0.9997 221125_WJC_METTL3_EV_vs_WT_F07.09806.09806.3 0.000792 Dec-40 K.KEEELQGALAR.G sp|P35580|MYH10_HUMAN 1 1242.6568 0.65 97780 9806 3 1242.657233 415.2262 Myosin-10 OS=Homo sapiens OX=9606 GN=MYH10 PE=1 SV=3 4.79 2010 - 836402 - - - 0.3364 - 2.111 0.32 - 245.6 1 2 0 0.0004 11 0 0 0 8.87E+06 1.37E+07 - - - 4.2301 1 221125_WJC_METTL3_EV_vs_WT_F07.09810.09810.2 1.31E-07 13/24 F.STASDNQPTVTIK[136.11].V "sp|P11021|BIP_HUMAN,tr|A0A7P0TB36|A0A7P0TB36_HUMAN,tr|A0A7P0TAI0|A0A7P0TAI0_HUMAN" 3 1368.6976 2.08 97784 9810 2 1368.696422 685.3561 Endoplasmic reticulum chaperone BiP OS=Homo sapiens OX=9606 GN=HSPA5 PE=1 SV=2 5.55 2010.5 - 389099 - - - -0.8782 - 2.435 0.609 - 544.1 1 1 0 -0.0012 13 0 0 0 1.37E+07 6.58E+06 - - - 5.8228 0.9999 221125_WJC_METTL3_EV_vs_WT_F07.09814.09814.3 5.17E-05 Dec-56 R.ETPHSPGVEDAPIAK[136.11].V "sp|Q9UHB6|LIMA1_HUMAN,tr|F8VQE1|F8VQE1_HUMAN,tr|F8VS07|F8VS07_HUMAN" 3 1554.7769 1.81 97786 9814 3 1554.777974 519.2663 LIM domain and actin-binding protein 1 OS=Homo sapiens OX=9606 GN=LIMA1 PE=1 SV=1 4.65 2011 - 1.24E+06 - - - 0.667 - 2.033 0.49 - 109.6 1 2 0 0.001 15 0 0 0 3.13E+07 1.73E+07 - - - 5.8541 1 221125_WJC_METTL3_EV_vs_WT_F07.09824.09824.3 8.98E-05 Oct-40 R.NHYNEEMSNLR.N sp|P15924|DESP_HUMAN 1 1405.6045 15.72 97794 9824 3 1405.607103 469.5421 Desmoplakin OS=Homo sapiens OX=9606 GN=DSP PE=1 SV=3 5.4 2012.2 - 1.18E+06 - - - 1.8789 - 2.132 0.556 - 229.4 1 2 0 0.0026 11 0 0 0 3.03E+07 1.93E+06 - - - 6.8888 0.9991 221125_WJC_METTL3_EV_vs_WT_F07.09826.09826.3 0.00278 Nov-40 K.K[136.11]EEELQGALAR[166.11].G sp|P35580|MYH10_HUMAN 1 1260.6793 0.87 97796 9826 3 1260.681794 421.2337 Myosin-10 OS=Homo sapiens OX=9606 GN=MYH10 PE=1 SV=3 4.79 2012.3 - 1.03E+06 - - - 1.9902 - 2.049 0.299 - 268.7 1 2 0 0.0025 11 0 0 0 8.98E+06 1.03E+07 - - - 3.9107 0.9999 221125_WJC_METTL3_EV_vs_WT_F07.09827.09827.2 1.68E-05 13/20 R.RGGPISFSSSR.S sp|P35580|MYH10_HUMAN 1 1149.5891 0.84 97797 9827 2 1149.589327 575.8018 Myosin-10 OS=Homo sapiens OX=9606 GN=MYH10 PE=1 SV=3 12 2012.4 - 973124 - - - 0.2236 - 2.606 0.498 - 167.2 1 2 0 0.0003 11 0 0 0 1.55E+07 1.85E+07 - - - 5.3103 1 221125_WJC_METTL3_EV_vs_WT_F07.09828.09828.3 3.79E-06 15/40 R.RGGPISFSSSR.S sp|P35580|MYH10_HUMAN 1 1149.5891 0.82 97798 9828 3 1149.588501 384.2036 Myosin-10 OS=Homo sapiens OX=9606 GN=MYH10 PE=1 SV=3 12 2012.5 - 840727 - - - -0.495 - 2.827 0.514 - 343.4 1 2 0 -0.0006 11 0 0 0 1.47E+07 1.79E+07 - - - 7.2227 0.9998 221125_WJC_METTL3_EV_vs_WT_F07.09830.09830.3 1.35E-05 15/40 K.TSFGSLK[136.11]DEDR[166.11].L "sp|P49821|NDUV1_HUMAN,tr|G3V0I5|G3V0I5_HUMAN,tr|E9PMX3|E9PMX3_HUMAN,tr|E9PPS5|E9PPS5_HUMAN" 4 1271.6113 4.96 97800 9830 3 1271.610887 424.8777 "NADH dehydrogenase [ubiquinone] flavoprotein 1, mitochondrial OS=Homo sapiens OX=9606 GN=NDUFV1 PE=1 SV=4" 4.56 2012.8 - 406744 - - - -0.2973 - 2.872 0.427 - 461.6 1 2 1 -0.0004 11 0 0 0 3.01E+07 6.08E+06 - - - 6.2976 0.9654 221125_WJC_METTL3_EV_vs_WT_F07.09833.09833.3 0.0383 Aug-52 K.LSDEPVEAK[136.11]EDYTK[136.11].F "sp|Q5TBB1|RNH2B_HUMAN,tr|A0A087WXR7|A0A087WXR7_HUMAN,tr|A0A2R8Y6M7|A0A2R8Y6M7_HUMAN,tr|A0A2R8Y687|A0A2R8Y687_HUMAN,tr|A0A2R8YEH2|A0A2R8YEH2_HUMAN,tr|A0A2R8YCX2|A0A2R8YCX2_HUMAN,tr|A0A2R8YCJ4|A0A2R8YCJ4_HUMAN,tr|A0A2R8Y7R8|A0A2R8Y7R8_HUMAN,tr|A0A2R8Y4S2|A0A2R8Y4S2_HUMAN,tr|A0A2R8YEB4|A0A2R8YEB4_HUMAN,tr|A0A2R8Y6Q6|A0A2R8Y6Q6_HUMAN,tr|A0A2R8Y6Y1|A0A2R8Y6Y1_HUMAN,tr|A0A2R8Y4Y9|A0A2R8Y4Y9_HUMAN,tr|A0A2R8Y761|A0A2R8Y761_HUMAN,tr|A0A087WZJ6|A0A087WZJ6_HUMAN,tr|A0A2R8YGP2|A0A2R8YGP2_HUMAN" 16 1638.7959 2.82 97803 9833 3 1638.797915 547.2726 Ribonuclease H2 subunit B OS=Homo sapiens OX=9606 GN=RNASEH2B PE=1 SV=1 4.18 2013.2 - 226537 - - - 1.2009 - 1.669 0.196 - 79.5 1 2 1 0.002 14 0 0 0 4.17E+06 1.48E+06 - - - 2.0859 0.9962 221125_WJC_METTL3_EV_vs_WT_F07.09834.09834.2 1.49E-08 20-Sep R.NHYNEEMSNLR.N sp|P15924|DESP_HUMAN 1 1405.6045 144.57 97804 9834 2 1405.596973 703.8095 Desmoplakin OS=Homo sapiens OX=9606 GN=DSP PE=1 SV=3 5.4 2013.3 - 210391 - - - -5.328 - 2.028 0.473 - 265.6 1 2 0 -0.0075 11 0 0 0 7.27E+06 5.03E+04 - - - 4.445 0.9997 221125_WJC_METTL3_EV_vs_WT_F07.09841.09841.3 1.94E-06 13/44 R.IHSLTHLDSVTK[136.11].L "sp|P46736|BRCC3_HUMAN,tr|A0A0D9SF50|A0A0D9SF50_HUMAN,tr|A0A087WZR3|A0A087WZR3_HUMAN,tr|H9KVA9|H9KVA9_HUMAN" 4 1357.7445 0.72 97809 9841 3 1357.748614 453.5888 Lys-63-specific deubiquitinase BRCC36 OS=Homo sapiens OX=9606 GN=BRCC3 PE=1 SV=2 6.92 2014 - 516953 - - - 3.0197 - 2.321 0.427 - 147.8 1 2 0 0.0041 12 0 0 0 6.21E+06 8.68E+06 - - - 5.6334 0.9985 221125_WJC_METTL3_EV_vs_WT_F07.09842.09842.3 0.000382 14/48 K.IC[160.03]R[166.11]DPQTPVLQTK[136.11].H sp|Q9ULW0|TPX2_HUMAN 1 1572.8413 0.03 97810 9842 3 1572.844805 525.2877 Targeting protein for Xklp2 OS=Homo sapiens OX=9606 GN=TPX2 PE=1 SV=2 8.22 2014.2 - 506506 - - - 2.2399 - 2.294 0.365 - 406.4 1 2 1 0.0035 13 0 0 0 1.86E+05 7.20E+06 - - - 4.8596 0.9993 221125_WJC_METTL3_EV_vs_WT_F07.09846.09846.3 0.00346 Oct-40 R.NHYNEEMSNLR[166.11].N sp|P15924|DESP_HUMAN 1 1415.6127 15.62 97814 9846 3 1415.608677 472.8782 Desmoplakin OS=Homo sapiens OX=9606 GN=DSP PE=1 SV=3 5.4 2014.7 - 247531 - - - -2.8645 - 1.817 0.389 - 223.6 1 2 0 -0.0041 11 0 0 0 3.01E+07 1.93E+06 - - - 4.5723 0.9999 221125_WJC_METTL3_EV_vs_WT_F07.09847.09847.2 0.000322 13/26 R.QEAESQPC[160.03]TSTLPR[166.11].E "sp|Q6ZN17|LN28B_HUMAN,tr|A0A1B0GVD3|A0A1B0GVD3_HUMAN" 2 1612.7391 1.23 97815 9847 2 1612.740519 807.3768 Protein lin-28 homolog B OS=Homo sapiens OX=9606 GN=LIN28B PE=1 SV=1 4.53 2014.8 - 212353 - - - 0.9078 - 2.799 0.508 - 392.8 1 2 0 0.0015 14 0 0 0 5.01E+06 4.09E+06 - - - 5.3755 0.9972 221125_WJC_METTL3_EV_vs_WT_F07.09848.09848.2 0.000734 26-May R.DTPGHGSGWAETPR[166.11].T sp|O75533|SF3B1_HUMAN 1 1476.6621 1.44 97816 9848 2 1476.667786 739.3383 Splicing factor 3B subunit 1 OS=Homo sapiens OX=9606 GN=SF3B1 PE=1 SV=3 5.32 2014.9 - 172632 - - - 3.8336 - 1.397 0.484 - 45.3 1 2 0 0.0057 14 0 0 0 2.16E+06 1.51E+06 - - - 3.453 0.9999 221125_WJC_METTL3_EV_vs_WT_F07.09854.09854.3 9.62E-06 14/44 K.QGNLSSQVPLK[136.11]R[166.11].L sp|P78527|PRKDC_HUMAN 1 1343.764 0.67 97820 9854 3 1343.767437 448.9286 DNA-dependent protein kinase catalytic subunit OS=Homo sapiens OX=9606 GN=PRKDC PE=1 SV=3 11 2015.8 - 1.68E+06 - - - 2.5443 - 2.173 0.516 - 250.2 1 2 0 0.0034 12 0 0 0 1.47E+07 2.21E+07 - - - 6.4432 1 221125_WJC_METTL3_EV_vs_WT_F07.09855.09855.3 0.000517 17/52 K.GETVNDC[160.03]HAEIISR[166.11].R "sp|P55265|DSRAD_HUMAN,tr|A0A3B3IRQ9|A0A3B3IRQ9_HUMAN,tr|A0A3B3ISU1|A0A3B3ISU1_HUMAN,tr|A0A7P0Z4K3|A0A7P0Z4K3_HUMAN,tr|A0A7P0Z4F9|A0A7P0Z4F9_HUMAN" 5 1609.7394 0.9 97821 9855 3 1609.74341 537.5871 Double-stranded RNA-specific adenosine deaminase OS=Homo sapiens OX=9606 GN=ADAR PE=1 SV=4 4.65 2015.8 - 1.28E+06 - - - 2.4979 - 3.603 0.559 - 620.3 1 2 0 0.004 14 0 0 0 9.97E+06 1.11E+07 - - - 8.1775 0.9996 221125_WJC_METTL3_EV_vs_WT_F07.09856.09856.2 0.00021 20-Oct R.R[166.11]GGPISFSSSR[166.11].S sp|P35580|MYH10_HUMAN 1 1169.6056 0.84 97822 9856 2 1169.607881 585.8101 Myosin-10 OS=Homo sapiens OX=9606 GN=MYH10 PE=1 SV=3 12 2015.9 - 1.84E+06 - - - 1.9417 - 2.079 0.428 - 88.7 1 2 0 0.0023 11 0 0 0 1.55E+07 1.85E+07 - - - 4.1814 1 221125_WJC_METTL3_EV_vs_WT_F07.09858.09858.3 3.87E-07 16/52 K.GETVNDC[160.03]HAEIISR.R "sp|P55265|DSRAD_HUMAN,tr|A0A3B3IRQ9|A0A3B3IRQ9_HUMAN,tr|A0A3B3ISU1|A0A3B3ISU1_HUMAN,tr|A0A7P0Z4K3|A0A7P0Z4K3_HUMAN,tr|A0A7P0Z4F9|A0A7P0Z4F9_HUMAN" 5 1599.7311 0.9 97824 9858 3 1599.735349 534.251 Double-stranded RNA-specific adenosine deaminase OS=Homo sapiens OX=9606 GN=ADAR PE=1 SV=4 4.65 2016.1 - 901125 - - - 2.6442 - 3.348 0.514 - 520.5 1 2 0 0.0042 14 0 0 0 9.97E+06 1.11E+07 - - - 7.4807 1 221125_WJC_METTL3_EV_vs_WT_F07.09859.09859.3 2.69E-05 14/40 K.EAIEGTYIDKK.C "sp|P62280|RS11_HUMAN,tr|M0QZC5|M0QZC5_HUMAN" 2 1265.6503 0.76 97825 9859 3 1265.65091 422.8907 40S ribosomal protein S11 OS=Homo sapiens OX=9606 GN=RPS11 PE=1 SV=3 4.68 2016.1 - 881292 - - - 0.4559 - 2.458 0.469 - 298.5 1 2 0 0.0006 11 0 0 0 1.16E+07 1.52E+07 - - - 6.3236 0.9998 221125_WJC_METTL3_EV_vs_WT_F07.09863.09863.2 2.17E-06 22-Sep R.NSMPASSFQQQK.L "sp|Q9Y383|LC7L2_HUMAN,sp|Q9NQ29|LUC7L_HUMAN,tr|A8MYV2|A8MYV2_HUMAN,tr|A0A0A6YYJ8|A0A0A6YYJ8_HUMAN,tr|B8ZZ10|B8ZZ10_HUMAN" 5 1351.619 0.92 97829 9863 2 1351.617673 676.8168 Putative RNA-binding protein Luc7-like 2 OS=Homo sapiens OX=9606 GN=LUC7L2 PE=1 SV=2 8.75 2016.7 - 309861 - - - -1.018 - 1.969 0.539 - 244.9 1 2 0 -0.0014 12 0 0 0 3.06E+06 3.33E+06 - - - 4.8043 0.9967 221125_WJC_METTL3_EV_vs_WT_F07.09865.09865.2 0.00439 30-Jun K.SSTTTTPVQSGANVVK.L "sp|Q02086|SP2_HUMAN,tr|Q9BRW5|Q9BRW5_HUMAN" 2 1575.8104 0.79 97831 9865 2 1575.8108 788.9125 Transcription factor Sp2 OS=Homo sapiens OX=9606 GN=SP2 PE=1 SV=3 8.47 2016.9 - 246956 - - - 0.2443 - 1.213 0.259 - 62.8 1 2 0 0.0004 16 0 0 0 1.94E+06 2.44E+06 - - - 1.4286 0.9992 221125_WJC_METTL3_EV_vs_WT_F07.09869.09869.3 0.0108 Jul-60 R.SQMNSQTEDHALAPVR[166.11].N sp|O15091|MRPP3_HUMAN 1 1792.8402 -1 97835 9869 3 1792.839136 598.6207 Mitochondrial ribonuclease P catalytic subunit OS=Homo sapiens OX=9606 GN=PRORP PE=1 SV=2 5.3 2017.4 - 102965 - - - -0.5745 - 1.503 0.351 - 61.4 1 2 0 -0.001 16 0 0 0 0.00E+00 0.00E+00 - - - 3.4985 0.9686 221125_WJC_METTL3_EV_vs_WT_F07.09870.09870.2 2.09 20-Apr R.KAEYPFSSEQK.W "sp|P98194|AT2C1_HUMAN,tr|H0Y9V7|H0Y9V7_HUMAN,tr|H0Y8X9|H0Y8X9_HUMAN,tr|B4E2Q0|B4E2Q0_HUMAN,tr|H0Y9S7|H0Y9S7_HUMAN" 5 1312.6299 0.67 97836 9870 2 1312.629845 657.3222 Calcium-transporting ATPase type 2C member 1 OS=Homo sapiens OX=9606 GN=ATP2C1 PE=1 SV=3 6.14 2017.6 - 99773.6 - - - -0.0663 - 0.911 0.174 - 43.1 3 2 0 -0.0001 11 0 0 0 6.16E+05 9.24E+05 - - - -0.1392 1 221125_WJC_METTL3_EV_vs_WT_F07.09874.09874.3 3.26E-06 16/44 K.QGNLSSQVPLKR.L sp|P78527|PRKDC_HUMAN 1 1325.7415 0.59 97838 9874 3 1325.74458 442.9211 DNA-dependent protein kinase catalytic subunit OS=Homo sapiens OX=9606 GN=PRKDC PE=1 SV=3 11 2018 - 2.43E+06 - - - 2.287 - 2.706 0.518 - 310.8 1 2 0 0.003 12 0 0 0 1.47E+07 2.50E+07 - - - 7.0736 0.9996 221125_WJC_METTL3_EV_vs_WT_F07.09875.09875.3 0.000313 Sep-40 K.EAIEGTYIDK[136.11]K[136.11].C "sp|P62280|RS11_HUMAN,tr|M0QZC5|M0QZC5_HUMAN" 2 1281.6787 0.77 97839 9875 3 1281.681257 428.2335 40S ribosomal protein S11 OS=Homo sapiens OX=9606 GN=RPS11 PE=1 SV=3 4.68 2018.1 - 2.36E+06 - - - 1.9693 - 1.857 0.38 - 132.3 1 2 0 0.0025 11 0 0 0 1.16E+07 1.50E+07 - - - 4.5343 0.9999 221125_WJC_METTL3_EV_vs_WT_F07.09876.09876.3 0.00769 15/48 R.RVAEELALEQAKK.E "sp|Q9NX63|MIC19_HUMAN,tr|A0A286YEX5|A0A286YEX5_HUMAN,tr|F8WAR4|F8WAR4_HUMAN,tr|C9JRZ6|C9JRZ6_HUMAN" 4 1483.8358 1.66 97840 9876 3 1483.838044 495.6192 MICOS complex subunit MIC19 OS=Homo sapiens OX=9606 GN=CHCHD3 PE=1 SV=1 6.23 2018.2 - 947948 - - - 1.484 - 2.684 0.415 - 366.7 1 2 0 0.0022 13 0 0 0 4.25E+06 2.56E+06 - - - 5.8431 0.9999 221125_WJC_METTL3_EV_vs_WT_F07.09877.09877.2 3.96E-07 22-Nov R.NSMPASSFQQQK[136.11].L "sp|Q9Y383|LC7L2_HUMAN,sp|Q9NQ29|LUC7L_HUMAN,tr|A8MYV2|A8MYV2_HUMAN,tr|A0A0A6YYJ8|A0A0A6YYJ8_HUMAN,tr|B8ZZ10|B8ZZ10_HUMAN" 5 1359.6332 0.92 97841 9877 2 1359.633337 680.8239 Putative RNA-binding protein Luc7-like 2 OS=Homo sapiens OX=9606 GN=LUC7L2 PE=1 SV=2 8.75 2018.3 - 469858 - - - 0.0647 - 1.93 0.571 - 352.2 1 2 0 0.0001 12 0 0 0 3.06E+06 3.33E+06 - - - 4.9884 0.9996 221125_WJC_METTL3_EV_vs_WT_F07.09878.09878.2 1.61E-05 20-Oct K.EAIEGTYIDKK.C "sp|P62280|RS11_HUMAN,tr|M0QZC5|M0QZC5_HUMAN" 2 1265.6503 0.87 97842 9878 2 1265.653434 633.8324 40S ribosomal protein S11 OS=Homo sapiens OX=9606 GN=RPS11 PE=1 SV=3 4.68 2018.4 - 411939 - - - 2.4501 - 2.203 0.493 - 459.7 1 2 0 0.0031 11 0 0 0 2.35E+06 2.71E+06 - - - 4.818 0.9996 221125_WJC_METTL3_EV_vs_WT_F07.09879.09879.2 6.34E-09 15/26 R.QEAESQPC[160.03]TSTLPR.E "sp|Q6ZN17|LN28B_HUMAN,tr|A0A1B0GVD3|A0A1B0GVD3_HUMAN" 2 1602.7308 1.03 97843 9879 2 1602.734978 802.3727 Protein lin-28 homolog B OS=Homo sapiens OX=9606 GN=LIN28B PE=1 SV=1 4.53 2018.6 - 387714 - - - 2.6162 - 2.751 0.482 - 590.1 1 2 0 0.0042 14 0 0 0 3.71E+06 3.61E+06 - - - 5.1392 0.9995 221125_WJC_METTL3_EV_vs_WT_F07.09880.09880.2 0.000204 28-Aug R.INPPSSGGTSSSPIK.A "sp|P14859|PO2F1_HUMAN,tr|A0A0C4DG88|A0A0C4DG88_HUMAN,tr|A0A0A0MT46|A0A0A0MT46_HUMAN" 3 1427.7256 2.7 97844 9880 2 1427.72463 714.8701 "POU domain, class 2, transcription factor 1 OS=Homo sapiens OX=9606 GN=POU2F1 PE=1 SV=2" 8.75 2018.7 - 355901 - - - -0.6955 - 1.762 0.364 - 84.3 1 2 0 -0.001 15 0 0 0 4.77E+06 1.77E+06 - - - 3.1218 0.9998 221125_WJC_METTL3_EV_vs_WT_F07.09888.09888.2 1.61E-06 13/26 K.SNTEPQSPPIASPK.A "sp|P82094|TMF1_HUMAN,tr|F8WF45|F8WF45_HUMAN,tr|A0A2R8Y7M0|A0A2R8Y7M0_HUMAN" 3 1451.7256 1.78 97851 9888 2 1451.728278 726.8701 TATA element modulatory factor OS=Homo sapiens OX=9606 GN=TMF1 PE=1 SV=2 5.72 2019.7 - 1.42E+06 - - - 1.8289 - 2.276 0.586 - 524.2 1 2 0 0.0027 14 0 0 0 2.88E+07 1.62E+07 - - - 5.4322 0.9958 221125_WJC_METTL3_EV_vs_WT_F07.09889.09889.2 0.271 28-Jul K.QGGGGGGGSVPGIER[166.11].M "sp|P52272|HNRPM_HUMAN,tr|M0R019|M0R019_HUMAN,tr|A0A087X0X3|A0A087X0X3_HUMAN,tr|M0R2T0|M0R2T0_HUMAN" 4 1293.6301 2.6 97852 9889 2 1293.632382 647.8223 Heterogeneous nuclear ribonucleoprotein M OS=Homo sapiens OX=9606 GN=HNRNPM PE=1 SV=3 6 2019.8 - 211999 - - - 1.7663 - 1.32 0.276 - 68.3 1 2 0 0.0023 15 0 0 0 1.57E+06 6.05E+05 - - - 1.7614 0.9945 221125_WJC_METTL3_EV_vs_WT_F07.09890.09890.3 0.177 Sep-52 K.EAEKPAVPETAGIK.F sp|Q9NPF5|DMAP1_HUMAN 1 1438.7668 1.29 97853 9890 3 1438.769577 480.5962 DNA methyltransferase 1-associated protein 1 OS=Homo sapiens OX=9606 GN=DMAP1 PE=1 SV=1 4.79 2019.9 - 3.41E+06 - - - 1.9579 - 1.634 0.245 - 130.7 1 2 0 0.0028 14 0 0 0 2.59E+07 2.00E+07 - - - 2.5757 0.9904 221125_WJC_METTL3_EV_vs_WT_F07.09891.09891.2 4.70E-08 13/28 R.SDSPVPTAPTSGGPK[136.11].P "sp|Q86U44|MTA70_HUMAN,tr|B4E349|B4E349_HUMAN,tr|F5H6D8|F5H6D8_HUMAN,tr|B4DTN4|B4DTN4_HUMAN" 4 1404.6976 0.03 97854 9891 2 1404.69992 703.3561 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 5.55 2019.9 - 1.36E+06 - - - 1.6345 - 2.329 0.599 - 345.4 1 1 0 0.0023 15 0 0 0 2.02E+09 7.55E+10 - - - 5.543 1 221125_WJC_METTL3_EV_vs_WT_F07.09892.09892.3 1.99E-05 15/48 R.R[166.11]VAEELALEQAK[136.11]K[136.11].E "sp|Q9NX63|MIC19_HUMAN,tr|A0A286YEX5|A0A286YEX5_HUMAN,tr|F8WAR4|F8WAR4_HUMAN,tr|C9JRZ6|C9JRZ6_HUMAN" 4 1509.8725 3.19 97855 9892 3 1509.87436 504.2981 MICOS complex subunit MIC19 OS=Homo sapiens OX=9606 GN=CHCHD3 PE=1 SV=1 6.23 2020 - 643340 - - - 1.2239 - 3.091 0.539 - 418.2 1 2 0 0.0018 13 0 0 0 1.42E+07 4.45E+06 - - - 7.6085 0.9997 221125_WJC_METTL3_EV_vs_WT_F07.09893.09893.3 8.87E-06 Dec-40 R.TADK[136.11]GWQNSIR[166.11].H "sp|P85037|FOXK1_HUMAN,sp|Q01167|FOXK2_HUMAN,tr|E9PM37|E9PM37_HUMAN,tr|E9PPI7|E9PPI7_HUMAN" 4 1292.6592 1.06 97856 9893 3 1292.660743 431.8937 Forkhead box protein K1 OS=Homo sapiens OX=9606 GN=FOXK1 PE=1 SV=1 8.41 2020.2 - 585410 - - - 1.1797 - 2.203 0.451 - 246.8 1 2 1 0.0015 11 0 0 0 9.96E+06 9.39E+06 - - - 5.8115 0.9984 221125_WJC_METTL3_EV_vs_WT_F07.09894.09894.3 0.0343 Oct-40 K.EC[160.03]GEHFEEMAK.E "sp|Q6ZRP7|QSOX2_HUMAN,tr|H0Y430|H0Y430_HUMAN" 2 1365.5329 1.44 97857 9894 3 1365.537069 456.1849 Sulfhydryl oxidase 2 OS=Homo sapiens OX=9606 GN=QSOX2 PE=1 SV=3 4.48 2020.3 - 479251 - - - 3.0259 - 1.698 0.352 - 134.5 1 2 0 0.0041 11 0 0 0 2.61E+06 1.82E+06 - - - 3.9674 0.9995 221125_WJC_METTL3_EV_vs_WT_F07.09896.09896.2 0.000577 20-Nov K.EAIEGTYIDK[136.11]K[136.11].C "sp|P62280|RS11_HUMAN,tr|M0QZC5|M0QZC5_HUMAN" 2 1281.6787 0.87 97859 9896 2 1281.682417 641.8466 40S ribosomal protein S11 OS=Homo sapiens OX=9606 GN=RPS11 PE=1 SV=3 4.68 2020.6 - 375278 - - - 2.8744 - 2.304 0.466 - 602.1 1 2 0 0.0037 11 0 0 0 2.35E+06 2.71E+06 - - - 4.7396 0.9548 221125_WJC_METTL3_EV_vs_WT_F07.09898.09898.3 0.124 Sep-40 R.R[166.11]DDDEPGPWTK[136.11].E "sp|Q96T88|UHRF1_HUMAN,tr|A0A087WWG9|A0A087WWG9_HUMAN,tr|A0A087WTW0|A0A087WTW0_HUMAN,tr|A0A087WVR3|A0A087WVR3_HUMAN" 4 1332.6065 2.55 97861 9898 3 1332.606503 445.2094 E3 ubiquitin-protein ligase UHRF1 OS=Homo sapiens OX=9606 GN=UHRF1 PE=1 SV=1 4.23 2020.8 - 458902 - - - -0.0083 - 1.435 0.121 - 72.8 1 2 0 0 11 0 0 0 9.08E+06 3.55E+06 - - - 0.915 0.9992 221125_WJC_METTL3_EV_vs_WT_F07.09899.09899.2 6.04E-05 22-Nov R.QAASSLQQASLK[136.11].L "sp|P38646|GRP75_HUMAN,tr|A0A7I2V2S7|A0A7I2V2S7_HUMAN,tr|A0A7I2V2G2|A0A7I2V2G2_HUMAN,tr|A0A7I2V3F7|A0A7I2V3F7_HUMAN,tr|A0A7I2YQB2|A0A7I2YQB2_HUMAN,tr|D6RCD7|D6RCD7_HUMAN" 6 1238.671 0.09 97862 9899 2 1238.67562 620.3428 "Stress-70 protein, mitochondrial OS=Homo sapiens OX=9606 GN=HSPA9 PE=1 SV=2" 8.75 2020.9 - 250427 - - - 3.7177 - 2.521 0.511 - 431.5 1 2 0 0.0046 12 0 0 0 1.32E+05 1.48E+06 - - - 5.2467 0.9995 221125_WJC_METTL3_EV_vs_WT_F07.09903.09903.2 9.86E-06 22-Sep K.QGNLSSQVPLKR.L sp|P78527|PRKDC_HUMAN 1 1325.7415 -1 97866 9903 2 1325.744872 663.8781 DNA-dependent protein kinase catalytic subunit OS=Homo sapiens OX=9606 GN=PRKDC PE=1 SV=3 11 2021.4 - 156676 - - - 2.5073 - 1.921 0.496 - 323.3 1 2 0 0.0033 12 0 0 0 0.00E+00 0.00E+00 - - - 4.4212 0.9995 221125_WJC_METTL3_EV_vs_WT_F07.09905.09905.2 0.000144 26-Jul R.ESTGNMVTGQTVC[160.03]K[136.11].N "sp|Q15021|CND1_HUMAN,tr|E7EN77|E7EN77_HUMAN" 2 1518.6898 0.46 97868 9905 2 1518.691264 760.3522 Condensin complex subunit 1 OS=Homo sapiens OX=9606 GN=NCAPD2 PE=1 SV=3 6.09 2021.7 - 124115 - - - 0.9785 - 1.804 0.374 - 132.4 1 2 0 0.0015 14 0 0 0 4.52E+05 9.84E+05 - - - 3.2835 0.9997 221125_WJC_METTL3_EV_vs_WT_F07.09908.09908.2 4.57E-07 26-Dec K.SNTEPQSPPIASPK[136.11].A "sp|P82094|TMF1_HUMAN,tr|F8WF45|F8WF45_HUMAN,tr|A0A2R8Y7M0|A0A2R8Y7M0_HUMAN" 3 1459.7398 2.71 97870 9908 2 1459.743684 730.8772 TATA element modulatory factor OS=Homo sapiens OX=9606 GN=TMF1 PE=1 SV=2 5.72 2022.2 - 643775 - - - 2.645 - 2.21 0.617 - 435.3 1 2 0 0.0039 14 0 0 0 5.39E+07 1.99E+07 - - - 5.5869 1 221125_WJC_METTL3_EV_vs_WT_F07.09910.09910.3 3.41E-10 16/48 K.VDNDENEHQLSLR[166.11].T "sp|P06748|NPM_HUMAN,tr|A0A7I2V4G8|A0A7I2V4G8_HUMAN,tr|A0A7I2YQC0|A0A7I2YQC0_HUMAN,tr|A0A7I2V433|A0A7I2V433_HUMAN,tr|A0A7I2V579|A0A7I2V579_HUMAN,tr|A0A7I2V2X9|A0A7I2V2X9_HUMAN,tr|A0A7I2V3G5|A0A7I2V3G5_HUMAN,tr|A0A7I2V5S2|A0A7I2V5S2_HUMAN,tr|A0A7I2V3U2|A0A7I2V3U2_HUMAN,tr|E5RGW4|E5RGW4_HUMAN" 10 1577.7309 0.99 97872 9910 3 1577.732698 526.9176 Nucleophosmin OS=Homo sapiens OX=9606 GN=NPM1 PE=1 SV=2 4.31 2022.3 - 9.09E+06 - - - 1.1187 - 3.14 0.673 - 681.9 1 2 0 0.0018 13 0 0 0 2.23E+09 2.26E+09 - - - 9.1451 1 221125_WJC_METTL3_EV_vs_WT_F07.09911.09911.3 4.99E-08 13/48 K.VDNDENEHQLSLR.T "sp|P06748|NPM_HUMAN,tr|A0A7I2V4G8|A0A7I2V4G8_HUMAN,tr|A0A7I2YQC0|A0A7I2YQC0_HUMAN,tr|A0A7I2V433|A0A7I2V433_HUMAN,tr|A0A7I2V579|A0A7I2V579_HUMAN,tr|A0A7I2V2X9|A0A7I2V2X9_HUMAN,tr|A0A7I2V3G5|A0A7I2V3G5_HUMAN,tr|A0A7I2V5S2|A0A7I2V5S2_HUMAN,tr|A0A7I2V3U2|A0A7I2V3U2_HUMAN,tr|E5RGW4|E5RGW4_HUMAN" 10 1567.7227 0.99 97873 9911 3 1567.726962 523.5815 Nucleophosmin OS=Homo sapiens OX=9606 GN=NPM1 PE=1 SV=2 4.31 2022.4 - 6.58E+06 - - - 2.7422 - 3.125 0.574 - 352.5 1 2 0 0.0043 13 0 0 0 2.23E+09 2.26E+09 - - - 8.0277 1 221125_WJC_METTL3_EV_vs_WT_F07.09912.09912.3 0.000285 13/36 K.EHFAQFGHVR[166.11].R "sp|Q9GZT3|SLIRP_HUMAN,tr|H0YJW7|H0YJW7_HUMAN,tr|A0A087WUN7|A0A087WUN7_HUMAN,tr|G3V2S9|G3V2S9_HUMAN,tr|H0YJU7|H0YJU7_HUMAN,tr|H0YJ07|H0YJ07_HUMAN,tr|H0YJ40|H0YJ40_HUMAN,tr|G3V4X6|G3V4X6_HUMAN" 8 1236.6028 1.29 97874 9912 3 1236.604469 413.2082 "SRA stem-loop-interacting RNA-binding protein, mitochondrial OS=Homo sapiens OX=9606 GN=SLIRP PE=1 SV=1" 7.02 2022.5 - 1.23E+06 - - - 1.382 - 2.261 0.51 - 293.9 1 2 0 0.0017 10 0 0 0 1.23E+09 9.56E+08 - - - 6.608 1 221125_WJC_METTL3_EV_vs_WT_F07.09916.09916.3 1.33E-05 25/56 R.IMVHPHVTAVSEQPR.A sp|Q96T58|MINT_HUMAN 1 1699.8828 1.23 97878 9916 3 1699.887457 567.6349 Msx2-interacting protein OS=Homo sapiens OX=9606 GN=SPEN PE=1 SV=1 6.92 2023 - 365532 - - - 2.7343 - 3.788 0.517 - 1283.7 1 2 0 0.0046 15 0 0 0 8.50E+06 6.89E+06 - - - 7.778 1 221125_WJC_METTL3_EV_vs_WT_F07.09918.09918.3 1.32E-05 18/56 R.IMVHPHVTAVSEQPR[166.11].A sp|Q96T58|MINT_HUMAN 1 1709.8911 1.23 97880 9918 3 1709.894088 570.971 Msx2-interacting protein OS=Homo sapiens OX=9606 GN=SPEN PE=1 SV=1 6.92 2023.2 - 340106 - - - 1.7598 - 3.354 0.487 - 340.6 1 2 0 0.003 15 0 0 0 8.50E+06 6.89E+06 - - - 7.1265 0.998 221125_WJC_METTL3_EV_vs_WT_F07.09922.09922.3 0.021 Jul-48 K.EAC[160.03]DQHGPDLYPK[136.11].F sp|P36551|HEM6_HUMAN 1 1536.6758 1.23 97884 9922 3 1536.679223 513.2326 "Oxygen-dependent coproporphyrinogen-III oxidase, mitochondrial OS=Homo sapiens OX=9606 GN=CPOX PE=1 SV=3" 4.54 2023.8 - 219709 - - - 2.1996 - 1.351 0.362 - 48.3 1 2 0 0.0034 13 0 0 0 2.62E+07 2.13E+07 - - - 3.3907 1 221125_WJC_METTL3_EV_vs_WT_F07.09923.09923.2 2.31E-10 16/24 K.VDNDENEHQLSLR.T "sp|P06748|NPM_HUMAN,tr|A0A7I2V4G8|A0A7I2V4G8_HUMAN,tr|A0A7I2YQC0|A0A7I2YQC0_HUMAN,tr|A0A7I2V433|A0A7I2V433_HUMAN,tr|A0A7I2V579|A0A7I2V579_HUMAN,tr|A0A7I2V2X9|A0A7I2V2X9_HUMAN,tr|A0A7I2V3G5|A0A7I2V3G5_HUMAN,tr|A0A7I2V5S2|A0A7I2V5S2_HUMAN,tr|A0A7I2V3U2|A0A7I2V3U2_HUMAN,tr|E5RGW4|E5RGW4_HUMAN" 10 1567.7227 0.98 97885 9923 2 1567.726949 784.8686 Nucleophosmin OS=Homo sapiens OX=9606 GN=NPM1 PE=1 SV=2 4.31 2023.9 - 189947 - - - 2.7339 - 3.232 0.639 - 1228.3 1 2 0 0.0043 13 0 0 0 1.23E+08 1.26E+08 - - - 6.7701 1 221125_WJC_METTL3_EV_vs_WT_F07.09924.09924.2 4.63E-10 13/32 M.SQGAVANANSTPPPYER.T sp|Q96PK6|RBM14_HUMAN 1 1757.8333 3.44 97886 9924 2 1757.835558 879.9239 RNA-binding protein 14 OS=Homo sapiens OX=9606 GN=RBM14 PE=1 SV=2 5.72 2024 - 168586 - - - 1.2982 - 3.301 0.7 - 374.8 1 1 0 0.0023 17 0 0 0 2.80E+06 8.13E+05 - - - 7.1465 0.9995 221125_WJC_METTL3_EV_vs_WT_F07.09927.09927.2 0.000371 26-May R.ESTGNMVTGQTVC[160.03]K.N "sp|Q15021|CND1_HUMAN,tr|E7EN77|E7EN77_HUMAN" 2 1510.6756 -1 97889 9927 2 1510.674438 756.3451 Condensin complex subunit 1 OS=Homo sapiens OX=9606 GN=NCAPD2 PE=1 SV=3 6.09 2024.4 - 84583.2 - - - -0.7546 - 1.394 0.433 - 67.7 1 2 0 -0.0011 14 0 0 0 0.00E+00 0.00E+00 - - - 3.0724 1 221125_WJC_METTL3_EV_vs_WT_F07.09930.09930.2 1.71E-05 16/24 K.VDNDENEHQLSLR[166.11].T "sp|P06748|NPM_HUMAN,tr|A0A7I2V4G8|A0A7I2V4G8_HUMAN,tr|A0A7I2YQC0|A0A7I2YQC0_HUMAN,tr|A0A7I2V433|A0A7I2V433_HUMAN,tr|A0A7I2V579|A0A7I2V579_HUMAN,tr|A0A7I2V2X9|A0A7I2V2X9_HUMAN,tr|A0A7I2V3G5|A0A7I2V3G5_HUMAN,tr|A0A7I2V5S2|A0A7I2V5S2_HUMAN,tr|A0A7I2V3U2|A0A7I2V3U2_HUMAN,tr|E5RGW4|E5RGW4_HUMAN" 10 1577.7309 0.99 97890 9930 2 1577.730921 789.8727 Nucleophosmin OS=Homo sapiens OX=9606 GN=NPM1 PE=1 SV=2 4.31 2024.8 - 2.29E+06 - - - -0.0076 - 3.411 0.632 - 1214.3 1 2 0 0 13 0 0 0 1.23E+08 1.24E+08 - - - 6.8581 0.9987 221125_WJC_METTL3_EV_vs_WT_F07.09931.09931.3 0.057 Nov-36 R.RLAELSDYRR.L sp|Q96PK6|RBM14_HUMAN 1 1277.684 2.04 97891 9931 3 1277.683925 426.902 RNA-binding protein 14 OS=Homo sapiens OX=9606 GN=RBM14 PE=1 SV=2 8.74 2024.9 - 1.96E+06 - - - -0.0845 - 1.851 0.252 - 140.2 1 2 0 -0.0001 10 0 0 0 6.18E+07 3.02E+07 - - - 3.1477 0.9998 221125_WJC_METTL3_EV_vs_WT_F07.09932.09932.3 0.0119 14/36 R.R[166.11]LAELSDYR[166.11]R[166.11].L sp|Q96PK6|RBM14_HUMAN 1 1307.7088 2.04 97892 9932 3 1307.70958 436.9102 RNA-binding protein 14 OS=Homo sapiens OX=9606 GN=RBM14 PE=1 SV=2 8.74 2024.9 - 1.67E+06 - - - 0.5636 - 1.968 0.354 - 228.9 1 2 0 0.0007 10 0 0 0 6.18E+07 3.02E+07 - - - 4.4637 0.9999 221125_WJC_METTL3_EV_vs_WT_F07.09933.09933.3 0.000383 Nov-48 K.SEHPGLSIGDTAK[136.11].K "sp|P26583|HMGB2_HUMAN,tr|D6R9A6|D6R9A6_HUMAN" 2 1318.6608 0.24 97893 9933 3 1318.660806 440.5609 High mobility group protein B2 OS=Homo sapiens OX=9606 GN=HMGB2 PE=1 SV=2 5.3 2025 - 1.17E+06 - - - -0.0288 - 2.08 0.427 - 130.4 1 2 0 0 13 0 0 0 8.12E+07 3.33E+08 - - - 5.2863 1 221125_WJC_METTL3_EV_vs_WT_F07.09935.09935.2 1.17E-10 19/22 V.DNDENEHQLSLR.T "sp|P06748|NPM_HUMAN,tr|A0A7I2V4G8|A0A7I2V4G8_HUMAN,tr|A0A7I2YQC0|A0A7I2YQC0_HUMAN,tr|A0A7I2V433|A0A7I2V433_HUMAN,tr|A0A7I2V579|A0A7I2V579_HUMAN,tr|A0A7I2V2X9|A0A7I2V2X9_HUMAN,tr|A0A7I2V3G5|A0A7I2V3G5_HUMAN,tr|A0A7I2V5S2|A0A7I2V5S2_HUMAN,tr|A0A7I2V3U2|A0A7I2V3U2_HUMAN,tr|E5RGW4|E5RGW4_HUMAN" 10 1468.6542 1.13 97895 9935 2 1468.653248 735.3344 Nucleophosmin OS=Homo sapiens OX=9606 GN=NPM1 PE=1 SV=2 4.31 2025.2 - 760389 - - - -0.6816 - 3.613 0.706 - 2161.7 1 1 0 -0.001 12 0 0 0 3.60E+07 3.18E+07 - - - 7.635 1 221125_WJC_METTL3_EV_vs_WT_F07.09937.09937.3 1.09E-05 13/52 R.KPVSIVSPEPGTTR.D sp|Q969Y2|GTPB3_HUMAN 1 1466.8093 1.78 97897 9937 3 1466.809908 489.9437 "tRNA modification GTPase GTPBP3, mitochondrial OS=Homo sapiens OX=9606 GN=GTPBP3 PE=1 SV=2" 8.75 2025.4 - 991467 - - - 0.4193 - 2.506 0.485 - 233.7 1 2 0 0.0006 14 0 0 0 3.80E+07 2.14E+07 - - - 6.3885 0.9998 221125_WJC_METTL3_EV_vs_WT_F07.09941.09941.2 0.00076 18-Nov K.EHFAQFGHVR.R "sp|Q9GZT3|SLIRP_HUMAN,tr|H0YJW7|H0YJW7_HUMAN,tr|A0A087WUN7|A0A087WUN7_HUMAN,tr|G3V2S9|G3V2S9_HUMAN,tr|H0YJU7|H0YJU7_HUMAN,tr|H0YJ07|H0YJ07_HUMAN,tr|H0YJ40|H0YJ40_HUMAN,tr|G3V4X6|G3V4X6_HUMAN" 8 1226.5945 1.32 97901 9941 2 1226.592472 614.3045 "SRA stem-loop-interacting RNA-binding protein, mitochondrial OS=Homo sapiens OX=9606 GN=SLIRP PE=1 SV=1" 7.02 2026 - 496833 - - - -1.6452 - 2.209 0.472 - 610.6 1 2 0 -0.002 10 0 0 0 1.03E+08 7.83E+07 - - - 4.7388 0.9999 221125_WJC_METTL3_EV_vs_WT_F07.09942.09942.2 6.62E-06 18-Oct K.EHFAQFGHVR[166.11].R "sp|Q9GZT3|SLIRP_HUMAN,tr|H0YJW7|H0YJW7_HUMAN,tr|A0A087WUN7|A0A087WUN7_HUMAN,tr|G3V2S9|G3V2S9_HUMAN,tr|H0YJU7|H0YJU7_HUMAN,tr|H0YJ07|H0YJ07_HUMAN,tr|H0YJ40|H0YJ40_HUMAN,tr|G3V4X6|G3V4X6_HUMAN" 8 1236.6028 1.32 97902 9942 2 1236.601843 619.3087 "SRA stem-loop-interacting RNA-binding protein, mitochondrial OS=Homo sapiens OX=9606 GN=SLIRP PE=1 SV=1" 7.02 2026.1 - 478290 - - - -0.7415 - 1.928 0.547 - 417.6 1 2 0 -0.0009 10 0 0 0 1.03E+08 7.83E+07 - - - 4.9133 0.9999 221125_WJC_METTL3_EV_vs_WT_F07.09952.09952.3 0.000295 Dec-44 K.DLLHPSPEEEK[136.11]R[166.11].K sp|P42677|RS27_HUMAN 1 1466.7484 0.91 97910 9952 3 1466.747578 489.9234 40S ribosomal protein S27 OS=Homo sapiens OX=9606 GN=RPS27 PE=1 SV=3 4.83 2027.3 - 2.20E+06 - - - -0.5788 - 2.252 0.41 - 216 1 2 0 -0.0008 12 0 0 0 2.44E+08 2.68E+08 - - - 5.3611 0.9874 221125_WJC_METTL3_EV_vs_WT_F07.09955.09955.2 9.51E-08 28-Dec R.SDSPVPTAPTSGGPK.P "sp|Q86U44|MTA70_HUMAN,tr|B4E349|B4E349_HUMAN,tr|F5H6D8|F5H6D8_HUMAN,tr|B4DTN4|B4DTN4_HUMAN" 4 1396.6834 0.03 97913 9955 2 1396.680354 699.349 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 5.55 2027.7 - 859057 - - - -2.1981 - 2.401 0.595 - 262.2 1 1 0 -0.0031 15 0 0 0 2.02E+09 7.55E+10 - - - 5.5881 1 221125_WJC_METTL3_EV_vs_WT_F07.09967.09967.2 6.49E-10 15/20 D.NDENEHQLSLR[166.11].T "sp|P06748|NPM_HUMAN,tr|A0A7I2V4G8|A0A7I2V4G8_HUMAN,tr|A0A7I2YQC0|A0A7I2YQC0_HUMAN,tr|A0A7I2V433|A0A7I2V433_HUMAN,tr|A0A7I2V579|A0A7I2V579_HUMAN,tr|A0A7I2V2X9|A0A7I2V2X9_HUMAN,tr|A0A7I2V3G5|A0A7I2V3G5_HUMAN,tr|A0A7I2V5S2|A0A7I2V5S2_HUMAN,tr|A0A7I2V3U2|A0A7I2V3U2_HUMAN,tr|E5RGW4|E5RGW4_HUMAN" 10 1363.6356 0.72 97923 9967 2 1363.630696 682.8251 Nucleophosmin OS=Homo sapiens OX=9606 GN=NPM1 PE=1 SV=2 4.65 2029.1 - 911670 - - - -3.5787 - 2.996 0.579 - 1302.3 1 1 0 -0.0049 11 0 0 0 9.71E+06 1.34E+07 - - - 6.2844 0.9999 221125_WJC_METTL3_EV_vs_WT_F07.09968.09968.3 1.99E-05 16/52 K.GEEDEGEEKYEVVK.L "sp|Q7L3S4|ZN771_HUMAN,tr|I3L3L5|I3L3L5_HUMAN,tr|H3BRY2|H3BRY2_HUMAN" 3 1638.7261 1.42 97924 9968 3 1638.727014 547.2493 Zinc finger protein 771 OS=Homo sapiens OX=9606 GN=ZNF771 PE=1 SV=1 4.06 2029.2 - 1.03E+06 - - - 0.5718 - 2.565 0.508 - 353.1 1 2 1 0.0009 14 0 0 0 1.04E+07 7.28E+06 - - - 6.7067 1 221125_WJC_METTL3_EV_vs_WT_F07.09974.09974.3 2.63E-05 Dec-48 K.SEHPGLSIGDTAK.K "sp|P26583|HMGB2_HUMAN,tr|D6R9A6|D6R9A6_HUMAN" 2 1310.6466 0.24 97928 9974 3 1310.645347 437.8895 High mobility group protein B2 OS=Homo sapiens OX=9606 GN=HMGB2 PE=1 SV=2 5.3 2029.9 - 3.23E+06 - - - -0.9896 - 2.219 0.547 - 172.4 1 2 0 -0.0013 13 0 0 0 8.12E+07 3.33E+08 - - - 6.7992 1 221125_WJC_METTL3_EV_vs_WT_F07.09976.09976.3 6.69E-05 15/44 K.DLLHPSPEEEKR.K sp|P42677|RS27_HUMAN 1 1448.726 0.59 97930 9976 3 1448.72517 483.9159 40S ribosomal protein S27 OS=Homo sapiens OX=9606 GN=RPS27 PE=1 SV=3 4.83 2030 - 2.81E+06 - - - -0.5432 - 2.446 0.462 - 339.3 1 2 0 -0.0008 12 0 0 0 1.54E+08 2.61E+08 - - - 6.1699 0.9997 221125_WJC_METTL3_EV_vs_WT_F07.09979.09979.3 0.000105 13/52 K.GEEDEGEEK[136.11]YEVVK[136.11].L "sp|Q7L3S4|ZN771_HUMAN,tr|I3L3L5|I3L3L5_HUMAN,tr|H3BRY2|H3BRY2_HUMAN" 3 1654.7545 1.45 97933 9979 3 1654.751676 552.5921 Zinc finger protein 771 OS=Homo sapiens OX=9606 GN=ZNF771 PE=1 SV=1 4.06 2030.3 - 480316 - - - -1.6927 - 2.453 0.451 - 209 1 2 1 -0.0028 14 0 0 0 1.06E+07 7.31E+06 - - - 5.9521 0.9988 221125_WJC_METTL3_EV_vs_WT_F07.09980.09980.3 0.0176 Aug-32 R.HLYIC[160.03]DYHK.N sp|O75446|SAP30_HUMAN 1 1247.5757 0.78 97934 9980 3 1247.575343 416.8659 Histone deacetylase complex subunit SAP30 OS=Homo sapiens OX=9606 GN=SAP30 PE=1 SV=1 6.91 2030.4 - 364742 - - - -0.3086 - 1.625 0.284 - 87.2 1 2 0 -0.0004 9 0 0 0 2.94E+07 3.80E+07 - - - 3.1694 0.9949 221125_WJC_METTL3_EV_vs_WT_F07.09983.09983.3 0.000534 Dec-36 R.LR[166.11]EEIEELK[136.11]R[166.11].N sp|O60763|USO1_HUMAN 1 1341.7611 0.76 97935 9983 3 1341.754765 448.261 General vesicular transport factor p115 OS=Homo sapiens OX=9606 GN=USO1 PE=1 SV=2 4.95 2030.8 - 1.59E+06 - - - -4.6871 - 2.461 0.373 - 348 1 2 1 -0.0063 10 0 0 0 1.59E+07 2.09E+07 - - - 5.3269 1 221125_WJC_METTL3_EV_vs_WT_F07.09984.09984.3 1.95E-05 16/52 R.LQFQQQQNSIHAAK.Q "sp|Q6PJT7|ZC3HE_HUMAN,tr|G3V3Y4|G3V3Y4_HUMAN,tr|G3V256|G3V256_HUMAN,tr|G3V5I6|G3V5I6_HUMAN,tr|A0A3B3IT62|A0A3B3IT62_HUMAN,tr|H0YJA2|H0YJA2_HUMAN" 6 1639.8431 1.34 97936 9984 3 1639.842539 547.6216 Zinc finger CCCH domain-containing protein 14 OS=Homo sapiens OX=9606 GN=ZC3H14 PE=1 SV=1 8.76 2031 - 1.32E+06 - - - -0.3134 - 2.802 0.461 - 339.8 1 2 0 -0.0005 14 0 0 0 1.87E+07 1.40E+07 - - - 6.4177 0.9902 221125_WJC_METTL3_EV_vs_WT_F07.09985.09985.3 0.238 14/52 R.LQFQQQQNSIHAAK[136.11].Q "sp|Q6PJT7|ZC3HE_HUMAN,tr|G3V3Y4|G3V3Y4_HUMAN,tr|G3V256|G3V256_HUMAN,tr|G3V5I6|G3V5I6_HUMAN,tr|A0A3B3IT62|A0A3B3IT62_HUMAN,tr|H0YJA2|H0YJA2_HUMAN" 6 1647.8573 1.34 97937 9985 3 1647.852907 550.293 Zinc finger CCCH domain-containing protein 14 OS=Homo sapiens OX=9606 GN=ZC3H14 PE=1 SV=1 8.76 2031.1 - 1.46E+06 - - - -2.6374 - 2.178 0.167 - 244.9 1 2 0 -0.0043 14 0 0 0 1.87E+07 1.40E+07 - - - 2.4693 1 221125_WJC_METTL3_EV_vs_WT_F07.09986.09986.2 8.85E-09 16/26 K.QVQPQLQQEAEPQK.Q "sp|Q9ULV3|CIZ1_HUMAN,tr|Q5SYW2|Q5SYW2_HUMAN,tr|F5H2X7|F5H2X7_HUMAN,tr|H0Y5D5|H0Y5D5_HUMAN,tr|A0A494C0L7|A0A494C0L7_HUMAN,tr|Q9BTG3|Q9BTG3_HUMAN" 6 1649.8373 4.13 97938 9986 2 1649.834814 825.9259 Cip1-interacting zinc finger protein OS=Homo sapiens OX=9606 GN=CIZ1 PE=1 SV=2 4.53 2031.2 - 1.15E+06 - - - -1.5062 - 2.768 0.588 - 872.9 1 2 0 -0.0025 14 0 0 0 1.32E+08 3.19E+07 - - - 5.9381 0.9999 221125_WJC_METTL3_EV_vs_WT_F07.09990.09990.2 1.20E-06 14/26 K.QVQPQLQQEAEPQK[136.11].Q "sp|Q9ULV3|CIZ1_HUMAN,tr|Q5SYW2|Q5SYW2_HUMAN,tr|F5H2X7|F5H2X7_HUMAN,tr|H0Y5D5|H0Y5D5_HUMAN,tr|A0A494C0L7|A0A494C0L7_HUMAN,tr|Q9BTG3|Q9BTG3_HUMAN" 6 1657.8515 4.13 97942 9990 2 1657.848879 829.933 Cip1-interacting zinc finger protein OS=Homo sapiens OX=9606 GN=CIZ1 PE=1 SV=2 4.53 2031.7 - 443985 - - - -1.5804 - 2.705 0.561 - 524.2 1 2 0 -0.0026 14 0 0 0 1.32E+08 3.19E+07 - - - 5.6809 0.9948 221125_WJC_METTL3_EV_vs_WT_F07.09991.09991.3 0.0965 Sep-40 K.VK[136.11]DLVLSVHNR[166.11].A "sp|Q15020|SART3_HUMAN,tr|A0A499FI31|A0A499FI31_HUMAN" 2 1296.7633 3.6 97943 9991 3 1296.760497 433.2617 Squamous cell carcinoma antigen recognized by T-cells 3 OS=Homo sapiens OX=9606 GN=SART3 PE=1 SV=1 8.73 2031.8 - 495124 - - - -2.1538 - 1.717 0.328 - 99 1 2 1 -0.0028 11 0 0 0 2.28E+07 6.32E+06 - - - 3.7318 1 221125_WJC_METTL3_EV_vs_WT_F07.09995.09995.3 0.000655 14/36 K.EHFAQFGHVR.R "sp|Q9GZT3|SLIRP_HUMAN,tr|H0YJW7|H0YJW7_HUMAN,tr|A0A087WUN7|A0A087WUN7_HUMAN,tr|G3V2S9|G3V2S9_HUMAN,tr|H0YJU7|H0YJU7_HUMAN,tr|H0YJ07|H0YJ07_HUMAN,tr|H0YJ40|H0YJ40_HUMAN,tr|G3V4X6|G3V4X6_HUMAN" 8 1226.5945 1.29 97945 9995 3 1226.592871 409.8721 "SRA stem-loop-interacting RNA-binding protein, mitochondrial OS=Homo sapiens OX=9606 GN=SLIRP PE=1 SV=1" 7.02 2032.3 - 6.07E+07 - - - -1.3199 - 2.223 0.496 - 346 1 2 0 -0.0016 10 0 0 0 1.23E+09 9.57E+08 - - - 6.4025 0.9999 221125_WJC_METTL3_EV_vs_WT_F07.10003.10003.2 4.08E-06 24-Oct K.SEHPGLSIGDTAK.K "sp|P26583|HMGB2_HUMAN,tr|D6R9A6|D6R9A6_HUMAN" 2 1310.6466 0.19 97951 10003 2 1310.647248 656.3306 High mobility group protein B2 OS=Homo sapiens OX=9606 GN=HMGB2 PE=1 SV=2 5.3 2033.2 - 863298 - - - 0.4608 - 2.091 0.53 - 220.7 1 2 0 0.0006 13 0 0 0 1.33E+07 6.86E+07 - - - 4.8486 0.8712 221125_WJC_METTL3_EV_vs_WT_F07.10004.10004.3 0.0876 Dec-52 K.QVQPQLQQEAEPQK[136.11].Q "sp|Q9ULV3|CIZ1_HUMAN,tr|Q5SYW2|Q5SYW2_HUMAN,tr|F5H2X7|F5H2X7_HUMAN,tr|H0Y5D5|H0Y5D5_HUMAN,tr|A0A494C0L7|A0A494C0L7_HUMAN,tr|Q9BTG3|Q9BTG3_HUMAN" 6 1657.8515 3.83 97952 10004 3 1657.848506 553.6244 Cip1-interacting zinc finger protein OS=Homo sapiens OX=9606 GN=CIZ1 PE=1 SV=2 4.53 2033.3 - 667004 - - - -1.8053 - 1.81 0.038 - 82.6 1 2 0 -0.003 14 0 0 0 6.96E+07 1.82E+07 - - - 0.5396 0.9999 221125_WJC_METTL3_EV_vs_WT_F07.10008.10008.3 0.000504 13/32 R.HLYIC[160.03]DYHK[136.11].N sp|O75446|SAP30_HUMAN 1 1255.5899 0.78 97956 10008 3 1255.587315 419.5373 Histone deacetylase complex subunit SAP30 OS=Homo sapiens OX=9606 GN=SAP30 PE=1 SV=1 6.91 2033.6 - 1.12E+06 - - - -2.0811 - 2.042 0.466 - 253.7 1 2 0 -0.0026 9 0 0 0 2.94E+07 3.80E+07 - - - 5.8864 0.9999 221125_WJC_METTL3_EV_vs_WT_F07.10013.10013.3 4.09E-05 Dec-44 R.VSVADHSLHLSK[136.11].A "sp|Q13162|PRDX4_HUMAN,tr|A6NG45|A6NG45_HUMAN" 2 1299.7026 0.45 97959 10013 3 1299.700649 434.2415 Peroxiredoxin-4 OS=Homo sapiens OX=9606 GN=PRDX4 PE=1 SV=1 6.89 2034.2 - 1.39E+06 - - - -1.5396 - 2.772 0.417 - 186.8 1 2 0 -0.002 12 0 0 0 5.11E+07 1.14E+08 - - - 6.0147 0.9999 221125_WJC_METTL3_EV_vs_WT_F07.10014.10014.3 2.59E-06 Dec-40 K.SNSHAAIDWGK.M sp|Q7KZ85|SPT6H_HUMAN 1 1184.5574 1.28 97960 10014 3 1184.553522 395.8598 Transcription elongation factor SPT6 OS=Homo sapiens OX=9606 GN=SUPT6H PE=1 SV=2 6.46 2034.4 - 1.04E+06 - - - -3.3033 - 2.165 0.514 - 112.8 1 2 0 -0.0039 11 0 0 0 1.50E+07 1.17E+07 - - - 6.4638 0.9968 221125_WJC_METTL3_EV_vs_WT_F07.10019.10019.3 1.80E-05 15/56 R.SDSPVPTAPTSGGPK[136.11].P "sp|Q86U44|MTA70_HUMAN,tr|B4E349|B4E349_HUMAN,tr|F5H6D8|F5H6D8_HUMAN,tr|B4DTN4|B4DTN4_HUMAN" 4 1404.6976 0.02 97963 10019 3 1404.69591 469.2398 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 5.55 2035 - 4.74E+06 - - - -1.2202 - 2.609 0.5 - 285.7 1 1 0 -0.0017 15 0 0 0 1.28E+07 5.12E+08 - - - 6.6163 0.9995 221125_WJC_METTL3_EV_vs_WT_F07.10022.10022.3 0.0308 14/44 R.VSVADHSLHLSK.A "sp|Q13162|PRDX4_HUMAN,tr|A6NG45|A6NG45_HUMAN" 2 1291.6885 0.45 97965 10022 3 1291.685887 431.5701 Peroxiredoxin-4 OS=Homo sapiens OX=9606 GN=PRDX4 PE=1 SV=1 6.89 2035.3 - 1.11E+06 - - - -1.9842 - 2.647 0.27 - 305 1 2 0 -0.0026 12 0 0 0 5.11E+07 1.14E+08 - - - 4.2477 0.9999 221125_WJC_METTL3_EV_vs_WT_F07.10028.10028.3 0.00519 13/44 R.KGIQEAQVELQK.A "sp|Q6P996|PDXD1_HUMAN,tr|H3BND4|H3BND4_HUMAN" 2 1369.7565 0.75 97969 10028 3 1369.75652 457.5928 Pyridoxal-dependent decarboxylase domain-containing protein 1 OS=Homo sapiens OX=9606 GN=PDXDC1 PE=1 SV=2 6.14 2036 - 1.36E+06 - - - -0.0066 - 2.726 0.353 - 420.2 1 2 0 0 12 0 0 0 2.95E+07 3.94E+07 - - - 5.2553 0.9379 221125_WJC_METTL3_EV_vs_WT_F07.10029.10029.2 0.104 14-Aug L.KWLDSDAR.N "sp|P34913|HYES_HUMAN,tr|E5RFU2|E5RFU2_HUMAN,tr|E5RFH6|E5RFH6_HUMAN" 3 989.493 2024.32 97970 10029 2 989.491242 495.7538 Bifunctional epoxide hydrolase 2 OS=Homo sapiens OX=9606 GN=EPHX2 PE=1 SV=2 5.96 2036.1 - 2.89E+06 - - - -1.8211 - 1.538 0.344 - 347.5 1 1 0 -0.0018 8 0 0 0 1.43E+09 7.07E+05 - - - 2.8795 0.9997 221125_WJC_METTL3_EV_vs_WT_F07.10034.10034.2 0.00459 18-Aug K.NC[160.03]NDFQYESK[136.11].V "sp|Q04917|1433F_HUMAN,tr|A2IDB2|A2IDB2_HUMAN" 2 1311.5281 0.76 97973 10034 2 1311.526814 656.7713 14-3-3 protein eta OS=Homo sapiens OX=9606 GN=YWHAH PE=1 SV=4 4.37 2036.7 - 609797 - - - -0.9927 - 1.47 0.511 - 171.4 1 2 0 -0.0013 10 0 0 0 6.28E+06 8.24E+06 - - - 3.8902 0.9989 221125_WJC_METTL3_EV_vs_WT_F07.10043.10043.3 5.27E-07 33/68 S.LAASYAAQQHPQAAASYR[166.11].G sp|Q96PK6|RBM14_HUMAN 1 1912.9419 2.45 97979 10043 3 1912.943849 638.6546 RNA-binding protein 14 OS=Homo sapiens OX=9606 GN=RBM14 PE=1 SV=2 8.6 2037.8 - 1.01E+06 - - - 1.0037 - 3.979 0.582 - 1587.4 1 1 0 0.0019 18 0 0 0 1.41E+08 5.76E+07 - - - 8.4671 0.9995 221125_WJC_METTL3_EV_vs_WT_F07.10045.10045.3 0.00166 Sep-36 R.DLEFSHSDSR.D "sp|Q8IX01|SUGP2_HUMAN,tr|M0R216|M0R216_HUMAN,tr|M0R2Z9|M0R2Z9_HUMAN,tr|M0R3F6|M0R3F6_HUMAN" 4 1191.5156 1.38 97980 10045 3 1191.512808 398.1792 SURP and G-patch domain-containing protein 2 OS=Homo sapiens OX=9606 GN=SUGP2 PE=1 SV=2 4.54 2038 - 795201 - - - -2.3684 - 1.756 0.389 - 119.3 1 2 0 -0.0028 10 0 0 0 1.76E+07 1.27E+07 - - - 4.5205 0.9997 221125_WJC_METTL3_EV_vs_WT_F07.10047.10047.3 0.00268 13/40 K.YFHPPAHLQAR.L "sp|Q9NUK0|MBNL3_HUMAN,tr|B1AKI2|B1AKI2_HUMAN,tr|B1AKI6|B1AKI6_HUMAN,tr|B1AKI4|B1AKI4_HUMAN,tr|B1AKI5|B1AKI5_HUMAN" 5 1335.6836 2.16 97982 10047 3 1335.680309 446.2352 Muscleblind-like protein 3 OS=Homo sapiens OX=9606 GN=MBNL3 PE=1 SV=2 8.76 2038.2 - 2.30E+06 - - - -2.4931 - 2.528 0.349 - 273.9 1 2 0 -0.0033 11 0 0 0 6.77E+07 3.14E+07 - - - 5.0647 1 221125_WJC_METTL3_EV_vs_WT_F07.10054.10054.3 2.84E-13 24/68 S.LAASYAAQQHPQAAASYR.G sp|Q96PK6|RBM14_HUMAN 1 1902.9337 2.47 97985 10054 3 1902.927646 635.3185 RNA-binding protein 14 OS=Homo sapiens OX=9606 GN=RBM14 PE=1 SV=2 8.6 2039.2 - 2.77E+06 - - - -3.1599 - 4.386 0.633 - 660.1 1 1 0 -0.006 18 0 0 0 1.42E+08 5.76E+07 - - - 9.2771 0.999 221125_WJC_METTL3_EV_vs_WT_F07.10067.10067.3 0.17 Oct-56 R.LVAC[160.03]FQGQHGTDAER[166.11].R "sp|Q68EM7|RHG17_HUMAN,tr|I3L1S9|I3L1S9_HUMAN,tr|I3L4P0|I3L4P0_HUMAN,tr|C9IZD3|C9IZD3_HUMAN" 4 1697.7819 1.62 97992 10067 3 1697.779735 566.9346 Rho GTPase-activating protein 17 OS=Homo sapiens OX=9606 GN=ARHGAP17 PE=1 SV=1 5.32 2041 - 855542 - - - -1.2887 - 1.473 0.346 - 68.2 1 2 0 -0.0022 15 0 0 0 1.66E+07 1.03E+07 - - - 3.4076 1 221125_WJC_METTL3_EV_vs_WT_F07.10068.10068.3 7.72E-09 21/56 R.DLIHGAPVGK[136.11]PAANR[166.11].A "sp|Q14683|SMC1A_HUMAN,tr|G8JLG1|G8JLG1_HUMAN,tr|A0A6Q8PHC3|A0A6Q8PHC3_HUMAN" 3 1532.8542 1.22 97993 10068 3 1532.853343 511.9587 Structural maintenance of chromosomes protein 1A OS=Homo sapiens OX=9606 GN=SMC1A PE=1 SV=2 8.75 2041.1 - 1.38E+06 - - - -0.5787 - 3.589 0.568 - 460.9 1 2 0 -0.0009 15 0 0 0 4.95E+07 4.06E+07 - - - 8.2068 0.9999 221125_WJC_METTL3_EV_vs_WT_F07.10073.10073.3 2.11E-05 14/56 R.LTPQHDQIQTQPLGK.G sp|Q9NPI6|DCP1A_HUMAN 1 1702.9002 2.4 97996 10073 3 1702.895538 568.6407 mRNA-decapping enzyme 1A OS=Homo sapiens OX=9606 GN=DCP1A PE=1 SV=3 6.74 2041.8 - 1.65E+06 - - - -2.7571 - 2.732 0.484 - 202.9 1 2 0 -0.0047 15 0 0 0 3.20E+08 1.33E+08 - - - 6.5573 1 221125_WJC_METTL3_EV_vs_WT_F07.10085.10085.2 2.13E-06 14/26 K.SVTEQGAELSNEER.N "sp|P63104|1433Z_HUMAN,tr|E7EX29|E7EX29_HUMAN,tr|E5RIR4|E5RIR4_HUMAN,tr|E7EVZ2|E7EVZ2_HUMAN,tr|E5RGE1|E5RGE1_HUMAN,tr|E9PD24|E9PD24_HUMAN,tr|E7ESK7|E7ESK7_HUMAN" 7 1547.7063 2.25 98001 10085 2 1547.700544 774.8604 14-3-3 protein zeta\delta OS=Homo sapiens OX=9606 GN=YWHAZ PE=1 SV=1 4.09 2043.4 - 1.29E+06 - - - -3.7475 - 3.182 0.546 - 619.9 1 2 0 -0.0058 14 0 0 0 4.04E+07 1.79E+07 - - - 5.9766 0.9953 221125_WJC_METTL3_EV_vs_WT_F07.10086.10086.3 9.84E-06 17/44 K.SKVTLLEGDHVR.F "sp|O75534|CSDE1_HUMAN,tr|E9PLT0|E9PLT0_HUMAN" 2 1352.7412 0.6 98002 10086 3 1352.738099 451.921 Cold shock domain-containing protein E1 OS=Homo sapiens OX=9606 GN=CSDE1 PE=1 SV=2 6.47 2043.6 - 831791 - - - -2.302 - 2.373 0.265 - 216.8 1 2 1 -0.0031 12 0 0 0 4.68E+07 7.81E+07 - - - 3.8889 0.9996 221125_WJC_METTL3_EV_vs_WT_F07.10093.10093.3 0.000108 17/44 K.SKVTLLEGDHVR.F "sp|O75534|CSDE1_HUMAN,tr|E9PLT0|E9PLT0_HUMAN" 2 1352.7412 0.6 98005 10093 3 1352.742596 451.921 Cold shock domain-containing protein E1 OS=Homo sapiens OX=9606 GN=CSDE1 PE=1 SV=2 6.47 2044.5 - 1.19E+06 - - - 1.0224 - 2.676 0.372 - 372.8 1 2 1 0.0014 12 0 0 0 4.68E+07 7.81E+07 - - - 5.4154 1 221125_WJC_METTL3_EV_vs_WT_F07.10094.10094.2 4.26E-07 15/24 K.LHVGNISPTC[160.03]TNK.E "sp|Q9BWF3|RBM4_HUMAN,tr|D6R9K7|D6R9K7_HUMAN,tr|J3QRR5|J3QRR5_HUMAN,tr|E9PB51|E9PB51_HUMAN" 4 1439.7191 1.24 98006 10094 2 1439.713358 720.8668 RNA-binding protein 4 OS=Homo sapiens OX=9606 GN=RBM4 PE=1 SV=1 8.23 2044.6 - 1.57E+06 - - - -3.9869 - 3.044 0.632 - 636.3 1 2 0 -0.0057 13 0 0 0 2.22E+08 1.79E+08 - - - 6.5641 0.9988 221125_WJC_METTL3_EV_vs_WT_F07.10105.10105.3 9.90E-05 15/60 K.LDSPAGTALSPSGHTK.L "sp|P32322|P5CR1_HUMAN,tr|E2QRB3|E2QRB3_HUMAN" 2 1537.7736 0.9 98011 10105 3 1537.76801 513.5985 "Pyrroline-5-carboxylate reductase 1, mitochondrial OS=Homo sapiens OX=9606 GN=PYCR1 PE=1 SV=2" 6.74 2046 - 1.25E+06 - - - -3.6585 - 2.959 0.294 - 304 1 2 0 -0.0056 16 0 0 0 5.30E+07 5.88E+07 - - - 4.5998 1 221125_WJC_METTL3_EV_vs_WT_F07.10106.10106.2 5.13E-07 14/26 K.SVTEQGAELSNEER[166.11].N "sp|P63104|1433Z_HUMAN,tr|E7EX29|E7EX29_HUMAN,tr|E5RIR4|E5RIR4_HUMAN,tr|E7EVZ2|E7EVZ2_HUMAN,tr|E5RGE1|E5RGE1_HUMAN,tr|E9PD24|E9PD24_HUMAN,tr|E7ESK7|E7ESK7_HUMAN" 7 1557.7146 2.25 98012 10106 2 1557.715766 779.8646 14-3-3 protein zeta\delta OS=Homo sapiens OX=9606 GN=YWHAZ PE=1 SV=1 4.09 2046.1 - 735532 - - - 0.7395 - 2.916 0.595 - 588.4 1 2 0 0.0012 14 0 0 0 4.04E+07 1.79E+07 - - - 6.121 1 221125_WJC_METTL3_EV_vs_WT_F07.10110.10110.3 0.00285 15/52 K.KPPLLNNADSVQAK.V "sp|P09874|PARP1_HUMAN,tr|A0A7I2V3E1|A0A7I2V3E1_HUMAN" 2 1493.8202 1.07 98014 10110 3 1493.818476 498.9473 Poly [ADP-ribose] polymerase 1 OS=Homo sapiens OX=9606 GN=PARP1 PE=1 SV=4 8.59 2046.6 - 1.94E+06 - - - -1.1487 - 2.963 0.484 - 452.7 1 2 0 -0.0017 14 0 0 0 1.74E+08 1.62E+08 - - - 6.8223 1 221125_WJC_METTL3_EV_vs_WT_F07.10114.10114.2 7.42E-07 22-Dec K.NNASTDYDLSDK[136.11].S "sp|P39023|RL3_HUMAN,tr|G5E9G0|G5E9G0_HUMAN,tr|B5MCW2|B5MCW2_HUMAN" 3 1349.5827 1.07 98016 10114 2 1349.579241 675.7986 60S ribosomal protein L3 OS=Homo sapiens OX=9606 GN=RPL3 PE=1 SV=2 3.93 2047 - 1.42E+06 - - - -2.5289 - 2.598 0.631 - 424 1 2 0 -0.0034 12 0 0 0 1.65E+08 1.54E+08 - - - 6.2126 0.9965 221125_WJC_METTL3_EV_vs_WT_F07.10115.10115.3 6.63E-09 22/52 K.HALLEADVAAHQDR.L "sp|Q13813|SPTN1_HUMAN,tr|A0A0D9SF54|A0A0D9SF54_HUMAN,tr|A0A0D9SGF6|A0A0D9SGF6_HUMAN" 3 1544.7696 1.89 98017 10115 3 1545.779496 515.9305 "Spectrin alpha chain, non-erythrocytic 1 OS=Homo sapiens OX=9606 GN=SPTAN1 PE=1 SV=3" 5.21 2047.1 - 1.48E+06 - - - 653.7817 - 4.534 0.499 - 879.4 1 2 0 1.0099 14 0 0 0 4.78E+07 2.52E+07 - - - 7.8407 0.9999 221125_WJC_METTL3_EV_vs_WT_F07.10116.10116.3 4.09E-05 15/40 R.QLTAHLQDVNR[166.11].E "sp|Q14203|DCTN1_HUMAN,tr|A0A804CDA6|A0A804CDA6_HUMAN,tr|E7EX90|E7EX90_HUMAN,tr|A0A7P0Z4C3|A0A7P0Z4C3_HUMAN,tr|Q6AWB1|Q6AWB1_HUMAN" 5 1303.6872 2.47 98018 10116 3 1303.686103 435.5697 Dynactin subunit 1 OS=Homo sapiens OX=9606 GN=DCTN1 PE=1 SV=3 6.74 2047.3 - 1.41E+06 - - - -0.8553 - 2.429 0.38 - 369.7 1 2 0 -0.0011 11 0 0 0 9.01E+07 3.64E+07 - - - 5.2975 1 221125_WJC_METTL3_EV_vs_WT_F07.10119.10119.3 3.68E-05 Dec-48 K.LHVGNISPTC[160.03]TNK[136.11].E "sp|Q9BWF3|RBM4_HUMAN,tr|D6R9K7|D6R9K7_HUMAN,tr|J3QRR5|J3QRR5_HUMAN,tr|E9PB51|E9PB51_HUMAN" 4 1447.7333 1.32 98019 10119 3 1447.732362 483.585 RNA-binding protein 4 OS=Homo sapiens OX=9606 GN=RBM4 PE=1 SV=1 8.23 2047.6 - 2.30E+07 - - - -0.6465 - 2.637 0.507 - 259.8 1 2 0 -0.0009 13 0 0 0 1.21E+09 9.15E+08 - - - 6.8213 1 221125_WJC_METTL3_EV_vs_WT_F07.10120.10120.3 8.27E-09 22/48 R.HLAEHSPYYEAMK.K "sp|Q12931|TRAP1_HUMAN,tr|I3L0K7|I3L0K7_HUMAN" 2 1574.7188 2.51 98020 10120 3 1574.717938 525.9135 "Heat shock protein 75 kDa, mitochondrial OS=Homo sapiens OX=9606 GN=TRAP1 PE=1 SV=3" 6 2047.8 - 2.67E+06 - - - -0.5245 - 3.705 0.644 - 656.8 1 2 0 -0.0008 13 0 0 0 1.00E+08 4.00E+07 - - - 9.2707 1 221125_WJC_METTL3_EV_vs_WT_F07.10121.10121.2 1.17E-09 22-Dec K.NNASTDYDLSDK.S "sp|P39023|RL3_HUMAN,tr|G5E9G0|G5E9G0_HUMAN,tr|B5MCW2|B5MCW2_HUMAN" 3 1341.5685 1.07 98021 10121 2 1341.565853 671.7915 60S ribosomal protein L3 OS=Homo sapiens OX=9606 GN=RPL3 PE=1 SV=2 3.93 2047.9 - 4.72E+06 - - - -1.9388 - 2.631 0.71 - 594.6 1 2 0 -0.0026 12 0 0 0 1.65E+08 1.54E+08 - - - 6.8295 0.9948 221125_WJC_METTL3_EV_vs_WT_F07.10126.10126.3 2.29E-06 15/40 C.SIC[160.03]DLPVHSNK.E "sp|P43243|MATR3_HUMAN,tr|A8MXP9|A8MXP9_HUMAN,tr|D6R991|D6R991_HUMAN,tr|A0A0R4J2E8|A0A0R4J2E8_HUMAN,tr|H0Y8T4|H0Y8T4_HUMAN,tr|D6REM6|D6REM6_HUMAN" 6 1268.6183 1.44 98024 10126 3 1268.615792 423.8801 Matrin-3 OS=Homo sapiens OX=9606 GN=MATR3 PE=1 SV=2 6.46 2048.5 - 841197 - - - -1.9935 - 2.206 0.522 - 216.5 1 1 0 -0.0025 11 0 0 0 4.51E+07 3.13E+07 - - - 6.6067 1 221125_WJC_METTL3_EV_vs_WT_F07.10127.10127.3 1.77E-09 23/52 K.HALLEADVAAHQDR[166.11].L "sp|Q13813|SPTN1_HUMAN,tr|A0A0D9SF54|A0A0D9SF54_HUMAN,tr|A0A0D9SGF6|A0A0D9SGF6_HUMAN" 3 1554.7778 1.89 98025 10127 3 1554.775763 519.2666 "Spectrin alpha chain, non-erythrocytic 1 OS=Homo sapiens OX=9606 GN=SPTAN1 PE=1 SV=3" 5.21 2048.6 - 1.64E+06 - - - -1.3256 - 4.003 0.641 - 985 1 2 0 -0.0021 14 0 0 0 4.78E+07 2.52E+07 - - - 9.3721 0.999 221125_WJC_METTL3_EV_vs_WT_F07.10128.10128.3 0.000723 Dec-36 K.K[136.11]IDK[136.11]YTEVLK[136.11].T "sp|P40429|RL13A_HUMAN,tr|M0QYS1|M0QYS1_HUMAN,tr|Q8J015|Q8J015_HUMAN,tr|A0A7I2V2L9|A0A7I2V2L9_HUMAN" 4 1259.7551 0.78 98026 10128 3 1259.751207 420.9257 60S ribosomal protein L13a OS=Homo sapiens OX=9606 GN=RPL13A PE=1 SV=2 8.43 2048.8 - 908637 - - - -3.1212 - 2.257 0.44 - 169.9 1 2 1 -0.0039 10 0 0 0 1.62E+07 2.07E+07 - - - 5.8218 1 221125_WJC_METTL3_EV_vs_WT_F07.10131.10131.3 2.65E-05 18/44 R.TLVAVK[136.11]PDGVQR[166.11].R "sp|O00746|NDKM_HUMAN,tr|Q4TT34|Q4TT34_HUMAN,tr|A0A087WVT9|A0A087WVT9_HUMAN,tr|H0Y6J0|H0Y6J0_HUMAN,tr|F2Z2X0|F2Z2X0_HUMAN" 5 1299.763 1.88 98027 10131 3 1299.760086 434.2616 "Nucleoside diphosphate kinase, mitochondrial OS=Homo sapiens OX=9606 GN=NME4 PE=1 SV=1" 8.41 2049.2 - 2.29E+06 - - - -2.2073 - 2.782 0.504 - 368.5 1 2 0 -0.0029 12 0 0 0 6.57E+07 3.50E+07 - - - 6.9944 1 221125_WJC_METTL3_EV_vs_WT_F07.10132.10132.2 9.06E-07 19/26 K.KPPLLNNADSVQAK.V "sp|P09874|PARP1_HUMAN,tr|A0A7I2V3E1|A0A7I2V3E1_HUMAN" 2 1493.8202 1.06 98028 10132 2 1493.815307 747.9174 Poly [ADP-ribose] polymerase 1 OS=Homo sapiens OX=9606 GN=PARP1 PE=1 SV=4 8.59 2049.3 - 1.01E+06 - - - -3.2701 - 3.572 0.572 - 978.8 1 2 0 -0.0049 14 0 0 0 2.57E+07 2.42E+07 - - - 6.4591 1 221125_WJC_METTL3_EV_vs_WT_F07.10133.10133.3 1.19E-05 16/44 R.TLVAVKPDGVQR.R "sp|O00746|NDKM_HUMAN,tr|Q4TT34|Q4TT34_HUMAN,tr|A0A087WVT9|A0A087WVT9_HUMAN,tr|H0Y6J0|H0Y6J0_HUMAN,tr|F2Z2X0|F2Z2X0_HUMAN" 5 1281.7405 1.87 98029 10133 3 1281.740337 428.2541 "Nucleoside diphosphate kinase, mitochondrial OS=Homo sapiens OX=9606 GN=NME4 PE=1 SV=1" 8.41 2049.4 - 2.40E+06 - - - -0.1155 - 2.676 0.517 - 283 1 2 0 -0.0001 12 0 0 0 6.54E+07 3.50E+07 - - - 7.0324 0.9997 221125_WJC_METTL3_EV_vs_WT_F07.10134.10134.3 0.000695 13/36 K.KIDKYTEVLK.T "sp|P40429|RL13A_HUMAN,tr|M0QYS1|M0QYS1_HUMAN,tr|Q8J015|Q8J015_HUMAN,tr|A0A7I2V2L9|A0A7I2V2L9_HUMAN" 4 1235.7125 0.78 98030 10134 3 1235.710601 412.9115 60S ribosomal protein L13a OS=Homo sapiens OX=9606 GN=RPL13A PE=1 SV=2 8.43 2049.6 - 891221 - - - -1.5683 - 2.709 0.41 - 273.2 1 2 1 -0.0019 10 0 0 0 1.62E+07 2.07E+07 - - - 6.021 0.9991 221125_WJC_METTL3_EV_vs_WT_F07.10136.10136.2 9.87E-06 28-Nov R.LTPQHDQIQTQPLGK.G sp|Q9NPI6|DCP1A_HUMAN 1 1702.9002 12.74 98032 10136 2 1702.895657 852.4574 mRNA-decapping enzyme 1A OS=Homo sapiens OX=9606 GN=DCP1A PE=1 SV=3 6.74 2049.8 - 605144 - - - -2.6872 - 1.905 0.425 - 287.5 1 2 0 -0.0046 15 0 0 0 7.28E+06 5.72E+05 - - - 3.7631 0.9944 221125_WJC_METTL3_EV_vs_WT_F07.10139.10139.2 4.44E-07 28-Dec R.SDSPVPTAPTSGGPK[136.11].P "sp|Q86U44|MTA70_HUMAN,tr|B4E349|B4E349_HUMAN,tr|F5H6D8|F5H6D8_HUMAN,tr|B4DTN4|B4DTN4_HUMAN" 4 1404.6976 0.03 98033 10139 2 1404.696982 703.3561 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 5.55 2050.2 - 3.76E+08 - - - -0.457 - 2.169 0.605 - 269.6 1 1 0 -0.0006 15 0 0 0 2.02E+09 7.55E+10 - - - 5.4129 1 221125_WJC_METTL3_EV_vs_WT_F07.10141.10141.2 9.24E-10 14/24 K.LHVGNISPTC[160.03]TNK[136.11].E "sp|Q9BWF3|RBM4_HUMAN,tr|D6R9K7|D6R9K7_HUMAN,tr|J3QRR5|J3QRR5_HUMAN,tr|E9PB51|E9PB51_HUMAN" 4 1447.7333 1.24 98035 10141 2 1447.730497 724.8739 RNA-binding protein 4 OS=Homo sapiens OX=9606 GN=RBM4 PE=1 SV=1 8.23 2050.3 - 7.11E+06 - - - -1.9347 - 2.764 0.686 - 484.8 1 2 0 -0.0028 13 0 0 0 2.22E+08 1.79E+08 - - - 6.7163 1 221125_WJC_METTL3_EV_vs_WT_F07.10142.10142.3 4.66E-06 15/40 R.R[166.11]PVHLDQAAFR[166.11].T sp|Q9H0D6|XRN2_HUMAN 1 1328.7216 0.78 98036 10142 3 1328.719367 443.9145 5'-3' exoribonuclease 2 OS=Homo sapiens OX=9606 GN=XRN2 PE=1 SV=1 9.61 2050.3 - 4.32E+06 - - - -1.7129 - 2.719 0.462 - 492.7 1 2 0 -0.0023 11 0 0 0 1.21E+08 1.55E+08 - - - 6.5318 0.9999 221125_WJC_METTL3_EV_vs_WT_F07.10145.10145.4 3.91E-05 Nov-78 K.LLYNR[166.11]PGTVSSLK[136.11]K[136.11].N "sp|P35659|DEK_HUMAN,tr|H0Y8X0|H0Y8X0_HUMAN,tr|H0Y993|H0Y993_HUMAN,tr|A0A494C028|A0A494C028_HUMAN,tr|D6RDA2|D6RDA2_HUMAN,tr|B4DFG0|B4DFG0_HUMAN" 6 1600.9511 0.55 98037 10145 4 1600.947883 401.2451 Protein DEK OS=Homo sapiens OX=9606 GN=DEK PE=1 SV=1 10.29 2050.7 - 764591 - - - -2.0076 - 2.079 0.437 - 67.1 1 2 0 -0.0032 14 0 0 0 1.32E+07 2.39E+07 - - - 3.2951 0.9925 221125_WJC_METTL3_EV_vs_WT_F07.10146.10146.3 0.0516 Sep-52 K.LLYNR[166.11]PGTVSSLK[136.11]K[136.11].N "sp|P35659|DEK_HUMAN,tr|H0Y8X0|H0Y8X0_HUMAN,tr|H0Y993|H0Y993_HUMAN,tr|A0A494C028|A0A494C028_HUMAN,tr|D6RDA2|D6RDA2_HUMAN,tr|B4DFG0|B4DFG0_HUMAN" 6 1600.9511 0.75 98038 10146 3 1600.948435 534.6576 Protein DEK OS=Homo sapiens OX=9606 GN=DEK PE=1 SV=1 10.29 2050.9 - 693965 - - - -1.6628 - 1.469 0.237 - 66.4 1 2 0 -0.0027 14 0 0 0 1.23E+07 1.66E+07 - - - 2.2036 0.9998 221125_WJC_METTL3_EV_vs_WT_F07.10148.10148.2 2.46E-06 15/26 K.K[136.11]PPLLNNADSVQAK[136.11].V "sp|P09874|PARP1_HUMAN,tr|A0A7I2V3E1|A0A7I2V3E1_HUMAN" 2 1509.8486 1.06 98040 10148 2 1509.84516 755.9316 Poly [ADP-ribose] polymerase 1 OS=Homo sapiens OX=9606 GN=PARP1 PE=1 SV=4 8.59 2051.1 - 734023 - - - -2.2731 - 2.675 0.563 - 542.3 1 2 0 -0.0034 14 0 0 0 2.57E+07 2.42E+07 - - - 5.6674 0.9996 221125_WJC_METTL3_EV_vs_WT_F07.10150.10150.3 0.000769 Sep-44 K.KQAEESMVASMR.L "sp|Q8N6H7|ARFG2_HUMAN,tr|E9PIY6|E9PIY6_HUMAN,tr|E9PQP3|E9PQP3_HUMAN,tr|G5E9L0|G5E9L0_HUMAN,tr|A0A0D9SF70|A0A0D9SF70_HUMAN" 5 1365.6381 0.34 98042 10150 3 1365.633786 456.22 ADP-ribosylation factor GTPase-activating protein 2 OS=Homo sapiens OX=9606 GN=ARFGAP2 PE=1 SV=1 6.14 2051.4 - 339491 - - - -3.137 - 2.15 0.406 - 88 1 2 0 -0.0043 12 0 0 0 7.20E+06 2.09E+07 - - - 5.1871 0.9522 221125_WJC_METTL3_EV_vs_WT_F07.10152.10152.2 1.82 20-Jun R.RPVHLDQAAFR.T sp|Q9H0D6|XRN2_HUMAN 1 1308.7051 0.64 98044 10152 2 1308.703228 655.3598 5'-3' exoribonuclease 2 OS=Homo sapiens OX=9606 GN=XRN2 PE=1 SV=1 9.61 2051.6 - 0 - - - -1.4327 - 1.202 0.07 - 38.4 3 2 0 -0.0019 11 0 0 0 4.45E+06 6.97E+06 - - - -0.158 0.9999 221125_WJC_METTL3_EV_vs_WT_F07.10156.10156.4 0.00135 13/78 K.LLYNRPGTVSSLKK.N "sp|P35659|DEK_HUMAN,tr|H0Y8X0|H0Y8X0_HUMAN,tr|H0Y993|H0Y993_HUMAN,tr|A0A494C028|A0A494C028_HUMAN,tr|D6RDA2|D6RDA2_HUMAN,tr|B4DFG0|B4DFG0_HUMAN" 6 1574.9144 0.55 98046 10156 4 1574.91269 394.7359 Protein DEK OS=Homo sapiens OX=9606 GN=DEK PE=1 SV=1 10.29 2052.1 - 1.03E+06 - - - -1.1029 - 2.244 0.415 - 85.8 1 2 0 -0.0017 14 0 0 0 1.32E+07 2.39E+07 - - - 3.1318 1 221125_WJC_METTL3_EV_vs_WT_F07.10157.10157.3 9.56E-07 15/40 R.KEMEQLVLDKK.Q sp|Q96A49|SYAP1_HUMAN 1 1359.7432 1.23 98047 10157 3 1359.741641 454.255 Synapse-associated protein 1 OS=Homo sapiens OX=9606 GN=SYAP1 PE=1 SV=1 6.18 2052.3 - 967247 - - - -1.137 - 2.723 0.566 - 417.8 1 2 0 -0.0015 11 0 0 0 3.79E+07 3.07E+07 - - - 7.6957 0.9998 221125_WJC_METTL3_EV_vs_WT_F07.10158.10158.2 0.000251 22-Oct R.TLVAVKPDGVQR.R "sp|O00746|NDKM_HUMAN,tr|Q4TT34|Q4TT34_HUMAN,tr|A0A087WVT9|A0A087WVT9_HUMAN,tr|H0Y6J0|H0Y6J0_HUMAN,tr|F2Z2X0|F2Z2X0_HUMAN" 5 1281.7405 3.15 98048 10158 2 1281.739739 641.8775 "Nucleoside diphosphate kinase, mitochondrial OS=Homo sapiens OX=9606 GN=NME4 PE=1 SV=1" 8.41 2052.4 - 670673 - - - -0.582 - 2.288 0.429 - 448.6 1 2 0 -0.0007 12 0 0 0 8.63E+06 2.74E+06 - - - 4.3871 1 221125_WJC_METTL3_EV_vs_WT_F07.10160.10160.3 0.000109 Dec-40 R.R[166.11]FHLGDAPGPR[166.11].E "sp|Q8N0Y2|ZN444_HUMAN,tr|K7EK55|K7EK55_HUMAN,tr|K7ELZ3|K7ELZ3_HUMAN,tr|K7EMV5|K7EMV5_HUMAN,tr|K7EJH4|K7EJH4_HUMAN,tr|K7ESL2|K7ESL2_HUMAN,tr|K7EJ91|K7EJ91_HUMAN" 7 1241.6532 1.51 98050 10160 3 1241.653438 414.8917 Zinc finger protein 444 OS=Homo sapiens OX=9606 GN=ZNF444 PE=1 SV=1 9.61 2052.7 - 281376 - - - 0.1683 - 2.679 0.466 - 169.7 1 2 0 0.0002 11 0 0 0 6.95E+06 4.59E+06 - - - 6.5349 0.9992 221125_WJC_METTL3_EV_vs_WT_F07.10163.10163.3 1.92E-06 Oct-48 K.VDNDENEHQLSLR.T "sp|P06748|NPM_HUMAN,tr|A0A7I2V4G8|A0A7I2V4G8_HUMAN,tr|A0A7I2YQC0|A0A7I2YQC0_HUMAN,tr|A0A7I2V433|A0A7I2V433_HUMAN,tr|A0A7I2V579|A0A7I2V579_HUMAN,tr|A0A7I2V2X9|A0A7I2V2X9_HUMAN,tr|A0A7I2V3G5|A0A7I2V3G5_HUMAN,tr|A0A7I2V5S2|A0A7I2V5S2_HUMAN,tr|A0A7I2V3U2|A0A7I2V3U2_HUMAN,tr|E5RGW4|E5RGW4_HUMAN" 10 1567.7227 0.99 98052 10163 3 1567.714163 523.5815 Nucleophosmin OS=Homo sapiens OX=9606 GN=NPM1 PE=1 SV=2 4.31 2053 - 1.27E+06 - - - -5.4219 - 2.383 0.476 - 140.8 1 2 0 -0.0085 13 0 0 0 2.23E+09 2.26E+09 - - - 6.199 0.9222 221125_WJC_METTL3_EV_vs_WT_F07.10165.10165.2 1.51E-06 20-Oct K.SKELTTEIDNN.L "sp|P13645|K1C10_HUMAN,tr|A0A1B0GVI3|A0A1B0GVI3_HUMAN" 2 1262.599 14.09 98053 10165 2 1262.599971 632.3068 "Keratin, type I cytoskeletal 10 OS=Homo sapiens OX=9606 GN=KRT10 PE=1 SV=6" 4.14 2053.2 - 1.74E+06 - - - 0.7485 - 2.391 0.503 - 325.5 1 1 1 0.0009 11 0 0 0 2.37E+07 1.68E+06 - - - 5.114 0.9999 221125_WJC_METTL3_EV_vs_WT_F07.10166.10166.2 0.000127 16-Sep K.VTMQNLNDR.L "sp|P13645|K1C10_HUMAN,sp|Q7Z3Z0|K1C25_HUMAN,sp|Q7Z3Y9|K1C26_HUMAN,sp|P02533|K1C14_HUMAN,sp|Q7Z3Y8|K1C27_HUMAN,sp|P08779|K1C16_HUMAN,sp|Q7Z3Y7|K1C28_HUMAN,tr|A0A1B0GVI3|A0A1B0GVI3_HUMAN" 8 1089.5237 314.77 98054 10166 2 1089.523447 545.7691 "Keratin, type I cytoskeletal 10 OS=Homo sapiens OX=9606 GN=KRT10 PE=1 SV=6" 5.81 2053.3 - 803106 - - - -0.2249 - 2.025 0.52 - 504.1 1 2 0 -0.0002 9 0 0 0 1.64E+07 5.21E+04 - - - 4.9229 1 221125_WJC_METTL3_EV_vs_WT_F07.10167.10167.3 5.76E-07 14/40 R.K[136.11]EMEQLVLDK[136.11]K[136.11].Q sp|Q96A49|SYAP1_HUMAN 1 1383.7858 1.25 98055 10167 3 1383.784873 462.2692 Synapse-associated protein 1 OS=Homo sapiens OX=9606 GN=SYAP1 PE=1 SV=1 6.18 2053.4 - 1.62E+06 - - - -0.6605 - 2.581 0.497 - 387.4 1 2 0 -0.0009 11 0 0 0 3.82E+07 3.07E+07 - - - 6.7744 0.998 221125_WJC_METTL3_EV_vs_WT_F07.10168.10168.3 0.0124 Sep-32 K.YK[136.11]PLDLR[166.11]PK[136.11].K sp|P42766|RL35_HUMAN 1 1154.7022 0.001 98056 10168 3 1154.700623 385.908 60S ribosomal protein L35 OS=Homo sapiens OX=9606 GN=RPL35 PE=1 SV=2 9.7 2053.5 - 984301 - - - -1.3649 - 1.843 0.243 - 90.3 2 2 0 -0.0016 9 0 0 0 0.00E+00 9.04E+07 - - - 2.9521 1 221125_WJC_METTL3_EV_vs_WT_F07.10169.10169.2 0.000458 13/26 R.GFSSGSAVVSGGSR.R sp|P35908|K22E_HUMAN 1 1253.6 1.74 98057 10169 2 1253.598957 627.8073 "Keratin, type II cytoskeletal 2 epidermal OS=Homo sapiens OX=9606 GN=KRT2 PE=1 SV=2" 9.75 2053.7 - 828007 - - - -0.8551 - 2.729 0.579 - 621.4 1 2 0 -0.0011 14 0 0 0 2.24E+07 1.28E+07 - - - 5.8365 0.9999 221125_WJC_METTL3_EV_vs_WT_F07.10174.10174.2 2.75E-05 24-Dec K.LNLGTDSDSSPQK.S "sp|Q16512|PKN1_HUMAN,tr|K7EN76|K7EN76_HUMAN" 2 1360.647 4.45 98062 10174 2 1360.648352 681.3308 Serine\threonine-protein kinase N1 OS=Homo sapiens OX=9606 GN=PKN1 PE=1 SV=2 4.21 2054.3 - 269731 - - - 0.9657 - 2.436 0.595 - 454.8 1 2 0 0.0013 13 0 0 0 4.02E+06 9.02E+05 - - - 5.7204 0.9986 221125_WJC_METTL3_EV_vs_WT_F07.10175.10175.2 0.0414 26-May R.AAQPPAQPC[160.03]QLC[160.03]GR[166.11].S "sp|Q96B54|ZN428_HUMAN,tr|M0QXZ5|M0QXZ5_HUMAN" 2 1562.7321 1.67 98063 10175 2 1562.732051 782.3733 Zinc finger protein 428 OS=Homo sapiens OX=9606 GN=ZNF428 PE=1 SV=2 8.11 2054.4 - 230537 - - - -0.0544 - 1.126 0.372 - 43.5 1 2 0 -0.0001 14 0 0 0 1.92E+06 1.15E+06 - - - 2.0864 0.9999 221125_WJC_METTL3_EV_vs_WT_F07.10177.10177.3 6.52E-06 Dec-56 R.LTPQHDQIQTQPLGK[136.11].G sp|Q9NPI6|DCP1A_HUMAN 1 1710.9144 2.4 98064 10177 3 1710.911609 571.3121 mRNA-decapping enzyme 1A OS=Homo sapiens OX=9606 GN=DCP1A PE=1 SV=3 6.74 2054.6 - 1.01E+06 - - - -1.6506 - 2.203 0.413 - 140.2 1 2 0 -0.0028 15 0 0 0 3.20E+08 1.33E+08 - - - 5.2047 1 221125_WJC_METTL3_EV_vs_WT_F07.10179.10179.3 6.77E-08 14/52 K.K[136.11]PPLLNNADSVQAK[136.11].V "sp|P09874|PARP1_HUMAN,tr|A0A7I2V3E1|A0A7I2V3E1_HUMAN" 2 1509.8486 1.07 98065 10179 3 1509.848338 504.2901 Poly [ADP-ribose] polymerase 1 OS=Homo sapiens OX=9606 GN=PARP1 PE=1 SV=4 8.59 2054.9 - 7.88E+06 - - - -0.1682 - 2.828 0.475 - 438 1 2 0 -0.0003 14 0 0 0 1.74E+08 1.62E+08 - - - 6.5984 0.9998 221125_WJC_METTL3_EV_vs_WT_F07.10180.10180.3 1.34E-05 13/40 R.KAEEVQAWAQR.K sp|Q9BYN8|RT26_HUMAN 1 1314.668 1.28 98066 10180 3 1314.669771 439.23 "28S ribosomal protein S26, mitochondrial OS=Homo sapiens OX=9606 GN=MRPS26 PE=1 SV=1" 6.14 2054.9 - 2.18E+06 - - - 1.3106 - 2.547 0.328 - 361.2 1 2 0 0.0017 11 0 0 0 6.63E+07 5.19E+07 - - - 4.8523 0.9997 221125_WJC_METTL3_EV_vs_WT_F07.10181.10181.2 9.79E-05 24-Oct K.GADVNAPPVPSSR[166.11].D "sp|O75179|ANR17_HUMAN,sp|Q8IWZ3|ANKH1_HUMAN,tr|E9PDP5|E9PDP5_HUMAN,tr|H0YM23|H0YM23_HUMAN,tr|H3BLS9|H3BLS9_HUMAN,tr|H0YLQ3|H0YLQ3_HUMAN,tr|H7C2F5|H7C2F5_HUMAN" 7 1275.6447 1.99 98067 10181 2 1275.646441 638.8296 Ankyrin repeat domain-containing protein 17 OS=Homo sapiens OX=9606 GN=ANKRD17 PE=1 SV=3 5.84 2055.1 - 583135 - - - 1.3773 - 1.879 0.449 - 266.3 1 2 0 0.0018 13 0 0 0 1.35E+07 6.78E+06 - - - 3.9756 0.9999 221125_WJC_METTL3_EV_vs_WT_F07.10184.10184.2 5.43E-06 15/20 R.K[136.11]AEEVQAWAQR[166.11].K sp|Q9BYN8|RT26_HUMAN 1 1332.6905 1.22 98070 10184 2 1332.688732 667.3525 "28S ribosomal protein S26, mitochondrial OS=Homo sapiens OX=9606 GN=MRPS26 PE=1 SV=1" 6.14 2055.4 - 321081 - - - -1.3401 - 2.842 0.442 - 941.2 1 2 0 -0.0018 11 0 0 0 9.93E+06 8.16E+06 - - - 5.1307 0.9991 221125_WJC_METTL3_EV_vs_WT_F07.10187.10187.3 0.00581 Sep-56 K.LITQTFSHHNQLAQK[136.11].T "sp|Q9Y266|NUDC_HUMAN,tr|A0A0A0MSS4|A0A0A0MSS4_HUMAN,tr|A0A0A0MSU9|A0A0A0MSU9_HUMAN" 3 1772.9413 1.68 98073 10187 3 1772.942041 591.9877 Nuclear migration protein nudC OS=Homo sapiens OX=9606 GN=NUDC PE=1 SV=1 8.76 2055.8 - 246517 - - - 0.4084 - 1.762 0.304 - 48.3 1 2 0 0.0007 15 0 0 0 8.46E+07 5.03E+07 - - - 3.4072 1 221125_WJC_METTL3_EV_vs_WT_F07.10189.10189.3 8.93E-05 18/40 R.RPVHLDQAAFR.T sp|Q9H0D6|XRN2_HUMAN 1 1308.7051 0.72 98074 10189 3 1308.704898 437.2423 5'-3' exoribonuclease 2 OS=Homo sapiens OX=9606 GN=XRN2 PE=1 SV=1 9.61 2056.1 - 5.94E+06 - - - -0.1566 - 3.041 0.514 - 740.7 1 2 0 -0.0002 11 0 0 0 1.05E+08 1.47E+08 - - - 7.4301 0.9997 221125_WJC_METTL3_EV_vs_WT_F07.10191.10191.4 0.00179 14/84 K.LTGVFAPR[166.11]PSTGPHK[136.11].L "sp|P62701|RS4X_HUMAN,sp|P22090|RS4Y1_HUMAN,sp|Q8TD47|RS4Y2_HUMAN,tr|C9JEH7|C9JEH7_HUMAN" 4 1581.8746 0.98 98075 10191 4 1581.876202 396.4759 "40S ribosomal protein S4, X isoform OS=Homo sapiens OX=9606 GN=RPS4X PE=1 SV=2" 11 2056.3 - 1.26E+06 - - - 0.9931 - 2.649 0.348 - 113.5 1 2 0 0.0016 15 0 0 0 1.30E+08 1.33E+08 - - - 2.6031 0.9962 221125_WJC_METTL3_EV_vs_WT_F07.10193.10193.3 0.000121 Dec-40 R.K[136.11]AEEVQAWAQR[166.11].K sp|Q9BYN8|RT26_HUMAN 1 1332.6905 1.28 98077 10193 3 1333.692138 445.2374 "28S ribosomal protein S26, mitochondrial OS=Homo sapiens OX=9606 GN=MRPS26 PE=1 SV=1" 6.14 2056.4 - 3.20E+06 - - - 751.5773 - 2.241 0.405 - 330 1 2 0 1.0016 11 0 0 0 6.63E+07 5.19E+07 - - - 5.0702 0.997 221125_WJC_METTL3_EV_vs_WT_F07.10194.10194.4 0.00736 13/84 K.LTGVFAPRPSTGPHK.L "sp|P62701|RS4X_HUMAN,sp|P22090|RS4Y1_HUMAN,sp|Q8TD47|RS4Y2_HUMAN,tr|C9JEH7|C9JEH7_HUMAN" 4 1563.8522 0.98 98078 10194 4 1563.853444 391.9703 "40S ribosomal protein S4, X isoform OS=Homo sapiens OX=9606 GN=RPS4X PE=1 SV=2" 11 2056.5 - 1.03E+06 - - - 0.8204 - 2.44 0.237 - 127.6 1 2 0 0.0013 15 0 0 0 1.30E+08 1.33E+08 - - - 1.6077 0.9984 221125_WJC_METTL3_EV_vs_WT_F07.10195.10195.3 5.91E-08 17/56 Y.LDDNQKPPVGEGLNR.K "sp|P52948|NUP98_HUMAN,tr|A0A3B3ITD8|A0A3B3ITD8_HUMAN" 2 1650.8325 2.09 98079 10195 3 1650.833838 551.2848 Nuclear pore complex protein Nup98-Nup96 OS=Homo sapiens OX=9606 GN=NUP98 PE=1 SV=4 4.56 2056.6 - 659343 - - - 0.7814 - 3.277 0.529 - 345.3 1 1 0 0.0013 15 0 0 0 7.63E+06 3.64E+06 - - - 7.5346 1 221125_WJC_METTL3_EV_vs_WT_F07.10196.10196.3 4.67E-08 19/56 K.LITQTFSHHNQLAQK.T "sp|Q9Y266|NUDC_HUMAN,tr|A0A0A0MSS4|A0A0A0MSS4_HUMAN,tr|A0A0A0MSU9|A0A0A0MSU9_HUMAN" 3 1764.9271 1.68 98080 10196 3 1764.928344 589.3163 Nuclear migration protein nudC OS=Homo sapiens OX=9606 GN=NUDC PE=1 SV=1 8.76 2056.8 - 552477 - - - 0.6952 - 3.608 0.553 - 354.1 1 2 0 0.0012 15 0 0 0 8.46E+07 5.03E+07 - - - 8.0533 1 221125_WJC_METTL3_EV_vs_WT_F07.10197.10197.3 2.52E-06 20/60 K.QLQQAQAAGAEQEVEK.F "sp|P39748|FEN1_HUMAN,tr|F5H1Y3|F5H1Y3_HUMAN" 2 1726.8486 0.72 98081 10197 3 1726.852711 576.6235 Flap endonuclease 1 OS=Homo sapiens OX=9606 GN=FEN1 PE=1 SV=1 4.25 2056.9 - 503547 - - - 2.3853 - 3.977 0.525 - 781.5 1 2 0 0.0041 16 0 0 0 1.60E+07 2.22E+07 - - - 7.9343 1 221125_WJC_METTL3_EV_vs_WT_F07.10198.10198.2 0.000336 14/20 R.KAEEVQAWAQR.K sp|Q9BYN8|RT26_HUMAN 1 1314.668 1.22 98082 10198 2 1314.670131 658.3413 "28S ribosomal protein S26, mitochondrial OS=Homo sapiens OX=9606 GN=MRPS26 PE=1 SV=1" 6.14 2057 - 480074 - - - 1.5844 - 2.855 0.525 - 764.4 1 2 0 0.0021 11 0 0 0 9.93E+06 8.16E+06 - - - 5.756 1 221125_WJC_METTL3_EV_vs_WT_F07.10199.10199.3 9.54E-06 17/56 K.LITQTFSHHNQLAQK[136.11].T "sp|Q9Y266|NUDC_HUMAN,tr|A0A0A0MSS4|A0A0A0MSS4_HUMAN,tr|A0A0A0MSU9|A0A0A0MSU9_HUMAN" 3 1772.9413 1.68 98083 10199 3 1772.943462 591.9877 Nuclear migration protein nudC OS=Homo sapiens OX=9606 GN=NUDC PE=1 SV=1 8.76 2057.2 - 468126 - - - 1.2099 - 3.128 0.575 - 265.6 1 2 0 0.0021 15 0 0 0 8.46E+07 5.03E+07 - - - 7.9258 0.9996 221125_WJC_METTL3_EV_vs_WT_F07.10200.10200.3 0.00402 13/52 R.LQEAQLYKEEGNQR.Y "sp|Q8N5M4|TTC9C_HUMAN,tr|E9PKV8|E9PKV8_HUMAN,tr|E7EST3|E7EST3_HUMAN" 3 1704.8431 1.22 98084 10200 3 1704.845098 569.2883 Tetratricopeptide repeat protein 9C OS=Homo sapiens OX=9606 GN=TTC9C PE=1 SV=1 4.79 2057.2 - 789630 - - - 1.1649 - 2.373 0.415 - 178.9 1 2 1 0.002 14 0 0 0 1.41E+07 1.16E+07 - - - 5.4628 1 221125_WJC_METTL3_EV_vs_WT_F07.10201.10201.2 4.39E-06 15/30 K.QLQQAQAAGAEQEVEK[136.11].F "sp|P39748|FEN1_HUMAN,tr|F5H1Y3|F5H1Y3_HUMAN" 2 1734.8628 0.59 98085 10201 2 1734.862017 868.4387 Flap endonuclease 1 OS=Homo sapiens OX=9606 GN=FEN1 PE=1 SV=1 4.25 2057.4 - 383722 - - - -0.4467 - 3.108 0.554 - 762.3 1 2 0 -0.0008 16 0 0 0 7.47E+06 1.26E+07 - - - 5.9205 0.9521 221125_WJC_METTL3_EV_vs_WT_F07.10204.10204.3 0.00177 Nov-56 Y.LDDNQK[136.11]PPVGEGLNR[166.11].K "sp|P52948|NUP98_HUMAN,tr|A0A3B3ITD8|A0A3B3ITD8_HUMAN" 2 1668.855 2.09 98088 10204 3 1668.858484 557.2923 Nuclear pore complex protein Nup98-Nup96 OS=Homo sapiens OX=9606 GN=NUP98 PE=1 SV=4 4.56 2057.7 - 250980 - - - 2.0769 - 2.353 0.328 - 127.5 1 1 0 0.0035 15 0 0 0 7.63E+06 3.64E+06 - - - 4.4287 1 221125_WJC_METTL3_EV_vs_WT_F07.10205.10205.2 0.000912 18/30 K.QLQQAQAAGAEQEVEK.F "sp|P39748|FEN1_HUMAN,tr|F5H1Y3|F5H1Y3_HUMAN" 2 1726.8486 0.59 98089 10205 2 1726.84537 864.4316 Flap endonuclease 1 OS=Homo sapiens OX=9606 GN=FEN1 PE=1 SV=1 4.25 2057.9 - 165744 - - - -1.8658 - 3.572 0.563 - 1278.9 1 2 0 -0.0032 16 0 0 0 7.47E+06 1.26E+07 - - - 6.3283 0.9741 221125_WJC_METTL3_EV_vs_WT_F07.10208.10208.2 4.95E-06 28-Aug R.SDSPVPTAPTSGGPK.P "sp|Q86U44|MTA70_HUMAN,tr|B4E349|B4E349_HUMAN,tr|F5H6D8|F5H6D8_HUMAN,tr|B4DTN4|B4DTN4_HUMAN" 4 1396.6834 0.03 98091 10208 2 1396.683831 699.349 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 5.55 2058.2 - 296099 - - - 0.2914 - 1.698 0.385 - 135 1 1 0 0.0004 15 0 0 0 2.02E+09 7.54E+10 - - - 3.1862 0.9999 221125_WJC_METTL3_EV_vs_WT_F07.10209.10209.3 0.000261 Dec-40 R.K[136.11]AEEVQAWAQR[166.11].K sp|Q9BYN8|RT26_HUMAN 1 1332.6905 1.28 98092 10209 3 1332.691642 445.2374 "28S ribosomal protein S26, mitochondrial OS=Homo sapiens OX=9606 GN=MRPS26 PE=1 SV=1" 6.14 2058.2 - 5.73E+06 - - - 0.8434 - 2.172 0.458 - 320.6 1 2 0 0.0011 11 0 0 0 6.63E+07 5.19E+07 - - - 5.8494 0.9995 221125_WJC_METTL3_EV_vs_WT_F07.10210.10210.3 2.18E-06 16/56 K.LTGVFAPR[166.11]PSTGPHK[136.11].L "sp|P62701|RS4X_HUMAN,sp|P22090|RS4Y1_HUMAN,sp|Q8TD47|RS4Y2_HUMAN,tr|C9JEH7|C9JEH7_HUMAN" 4 1581.8746 1.09 98093 10210 3 1581.880781 528.2988 "40S ribosomal protein S4, X isoform OS=Homo sapiens OX=9606 GN=RPS4X PE=1 SV=2" 11 2058.3 - 1.98E+06 - - - 3.8878 - 2.965 0.383 - 408.8 1 2 0 0.0062 15 0 0 0 8.00E+07 7.34E+07 - - - 5.6444 0.9996 221125_WJC_METTL3_EV_vs_WT_F07.10211.10211.3 0.114 14/52 R.DLEDKEGEIQAGAK.L "sp|Q13409|DC1I2_HUMAN,tr|E7EQL5|E7EQL5_HUMAN" 2 1501.726 0.97 98094 10211 3 1501.72681 501.5826 Cytoplasmic dynein 1 intermediate chain 2 OS=Homo sapiens OX=9606 GN=DYNC1I2 PE=1 SV=3 4.18 2058.3 - 1.86E+06 - - - 0.5281 - 2.262 0.419 - 172.8 1 2 1 0.0008 14 0 0 0 1.36E+07 1.41E+07 - - - 5.3804 1 221125_WJC_METTL3_EV_vs_WT_F07.10212.10212.3 1.69E-08 19/60 K.QLQQAQAAGAEQEVEK[136.11].F "sp|P39748|FEN1_HUMAN,tr|F5H1Y3|F5H1Y3_HUMAN" 2 1734.8628 0.72 98095 10212 3 1734.86358 579.2949 Flap endonuclease 1 OS=Homo sapiens OX=9606 GN=FEN1 PE=1 SV=1 4.25 2058.4 - 1.78E+06 - - - 0.4542 - 4.192 0.567 - 711.3 1 2 0 0.0008 16 0 0 0 1.60E+07 2.22E+07 - - - 8.5386 0.9998 221125_WJC_METTL3_EV_vs_WT_F07.10213.10213.3 0.00672 13/56 K.LTGVFAPRPSTGPHK.L "sp|P62701|RS4X_HUMAN,sp|P22090|RS4Y1_HUMAN,sp|Q8TD47|RS4Y2_HUMAN,tr|C9JEH7|C9JEH7_HUMAN" 4 1563.8522 1.09 98096 10213 3 1563.853092 522.2913 "40S ribosomal protein S4, X isoform OS=Homo sapiens OX=9606 GN=RPS4X PE=1 SV=2" 11 2058.5 - 1.67E+06 - - - 0.5953 - 2.531 0.339 - 211.9 1 2 0 0.0009 15 0 0 0 8.00E+07 7.34E+07 - - - 4.7424 0.9996 221125_WJC_METTL3_EV_vs_WT_F07.10214.10214.3 6.03E-05 Nov-52 R.DLEDK[136.11]EGEIQAGAK[136.11].L "sp|Q13409|DC1I2_HUMAN,tr|E7EQL5|E7EQL5_HUMAN" 2 1517.7544 0.95 98097 10214 3 1517.755809 506.9254 Cytoplasmic dynein 1 intermediate chain 2 OS=Homo sapiens OX=9606 GN=DYNC1I2 PE=1 SV=3 4.18 2058.5 - 1.59E+06 - - - 0.9171 - 2.058 0.443 - 90.5 1 2 1 0.0014 14 0 0 0 1.36E+07 1.44E+07 - - - 5.3967 1 221125_WJC_METTL3_EV_vs_WT_F07.10216.10216.3 9.32E-07 13/48 K.GPSTVTDLEDTKR.D "sp|O94973|AP2A2_HUMAN,tr|A0A0G2JS82|A0A0G2JS82_HUMAN,tr|A0A0G2JQM1|A0A0G2JQM1_HUMAN" 3 1417.7049 0.55 98099 10216 3 1417.706238 473.5756 AP-2 complex subunit alpha-2 OS=Homo sapiens OX=9606 GN=AP2A2 PE=1 SV=2 4.56 2058.7 - 597022 - - - 0.9522 - 2.905 0.461 - 275.1 1 2 0 0.0014 13 0 0 0 4.59E+06 8.38E+06 - - - 6.5707 1 221125_WJC_METTL3_EV_vs_WT_F07.10219.10219.3 0.000185 15/60 K.QLLTPATGAPK[136.11]PQGTK[136.11].L "sp|O95602|RPA1_HUMAN,tr|B9ZVN9|B9ZVN9_HUMAN" 2 1622.9327 0.75 98102 10219 3 1622.933071 541.9848 DNA-directed RNA polymerase I subunit RPA1 OS=Homo sapiens OX=9606 GN=POLR1A PE=1 SV=2 10 2059.1 - 465828 - - - 0.2557 - 2.812 0.425 - 372.7 1 2 0 0.0004 16 0 0 0 6.87E+06 9.11E+06 - - - 5.9311 0.9961 221125_WJC_METTL3_EV_vs_WT_F07.10220.10220.3 0.0078 Oct-60 K.QLLTPATGAPKPQGTK.L "sp|O95602|RPA1_HUMAN,tr|B9ZVN9|B9ZVN9_HUMAN" 2 1606.9043 0.75 98103 10220 3 1606.909857 536.642 DNA-directed RNA polymerase I subunit RPA1 OS=Homo sapiens OX=9606 GN=POLR1A PE=1 SV=2 10 2059.2 - 325646 - - - 3.4856 - 2.145 0.274 - 84.7 1 2 0 0.0056 16 0 0 0 6.87E+06 9.11E+06 - - - 3.5514 0.9465 221125_WJC_METTL3_EV_vs_WT_F07.10221.10221.3 0.206 Jul-40 R.RDEYGLPSQPK.Q "sp|Q8IZH2|XRN1_HUMAN,tr|H7C5E4|H7C5E4_HUMAN" 2 1288.6412 17.31 98104 10221 3 1288.646545 430.5543 5'-3' exoribonuclease 1 OS=Homo sapiens OX=9606 GN=XRN1 PE=1 SV=1 6.07 2059.3 - 257907 - - - 4.1749 - 1.45 0.225 - 48.6 1 2 0 0.0054 11 0 0 0 7.23E+06 4.17E+05 - - - 2.1026 0.9998 221125_WJC_METTL3_EV_vs_WT_F07.10224.10224.2 1.61E-05 26-Aug K.DALNENSQLQESQK[136.11].Q "sp|Q96PC5|MIA2_HUMAN,tr|G3V599|G3V599_HUMAN" 2 1610.7627 0.65 98107 10224 2 1610.762056 806.3886 Melanoma inhibitory activity protein 2 OS=Homo sapiens OX=9606 GN=MIA2 PE=1 SV=4 4.14 2059.7 - 120175 - - - -0.4265 - 1.914 0.484 - 91.5 1 2 0 -0.0007 14 0 0 0 5.74E+05 8.76E+05 - - - 4.2447 0.9999 221125_WJC_METTL3_EV_vs_WT_F07.10227.10227.4 3.70E-05 Dec-84 K.LITQTFSHHNQLAQK.T "sp|Q9Y266|NUDC_HUMAN,tr|A0A0A0MSS4|A0A0A0MSS4_HUMAN,tr|A0A0A0MSU9|A0A0A0MSU9_HUMAN" 3 1764.9271 1.58 98108 10227 4 1764.929282 442.2391 Nuclear migration protein nudC OS=Homo sapiens OX=9606 GN=NUDC PE=1 SV=1 8.76 2060.1 - 4.46E+06 - - - 1.2267 - 2.297 0.445 - 107 1 2 0 0.0022 15 0 0 0 7.40E+07 4.68E+07 - - - 3.3962 0.9998 221125_WJC_METTL3_EV_vs_WT_F07.10228.10228.3 8.38E-05 14/60 K.TANLAEANASEEDK[136.11]IK[136.11].A "sp|Q7Z6E9|RBBP6_HUMAN,tr|A0A2R8Y880|A0A2R8Y880_HUMAN,tr|I3L3Y2|I3L3Y2_HUMAN,tr|H3BUN0|H3BUN0_HUMAN" 4 1718.8658 2.22 98109 10228 3 1718.862982 573.9625 E3 ubiquitin-protein ligase RBBP6 OS=Homo sapiens OX=9606 GN=RBBP6 PE=1 SV=1 4.41 2060.2 - 1.40E+06 - - - -1.615 - 3.207 0.428 - 178.3 1 2 1 -0.0028 16 0 0 0 1.69E+07 7.61E+06 - - - 6.3011 0.9998 221125_WJC_METTL3_EV_vs_WT_F07.10229.10229.3 2.44E-05 16/36 R.LKDIDEDFKR.E "sp|Q8NHH9|ATLA2_HUMAN,tr|B5MCN0|B5MCN0_HUMAN,tr|H7C3A2|H7C3A2_HUMAN,tr|C9JQQ5|C9JQQ5_HUMAN" 4 1277.6616 0.87 98110 10229 3 1277.663948 426.8945 Atlastin-2 OS=Homo sapiens OX=9606 GN=ATL2 PE=1 SV=2 4.68 2060.3 - 752539 - - - 1.8643 - 2.997 0.466 - 388.6 1 2 1 0.0024 10 0 0 0 4.54E+06 5.22E+06 - - - 6.9403 0.9966 221125_WJC_METTL3_EV_vs_WT_F07.10235.10235.3 0.0295 Oct-60 R.GASTFKEEPQTVPEAR.S sp|P17275|JUNB_HUMAN 1 1745.8584 17.55 98116 10235 3 1745.861287 582.9601 Transcription factor jun-B OS=Homo sapiens OX=9606 GN=JUNB PE=1 SV=1 4.79 2061.1 - 270528 - - - 1.6376 - 1.922 0.326 - 115.1 1 2 1 0.0029 16 0 0 0 1.93E+06 1.10E+05 - - - 3.8502 0.9999 221125_WJC_METTL3_EV_vs_WT_F07.10240.10240.3 1.52E-06 13/48 K.LHVGNISPTC[160.03]TNK.E "sp|Q9BWF3|RBM4_HUMAN,tr|D6R9K7|D6R9K7_HUMAN,tr|J3QRR5|J3QRR5_HUMAN,tr|E9PB51|E9PB51_HUMAN" 4 1439.7191 1.31 98120 10240 3 1439.722091 480.9136 RNA-binding protein 4 OS=Homo sapiens OX=9606 GN=RBM4 PE=1 SV=1 8.23 2061.7 - 3.08E+06 - - - 2.0789 - 2.436 0.496 - 321.7 1 2 0 0.003 13 0 0 0 1.25E+09 9.53E+08 - - - 6.4831 0.9955 221125_WJC_METTL3_EV_vs_WT_F07.10242.10242.3 2.67E-05 Dec-44 K.LDLR[166.11]DDK[136.11]DTIEK[136.11].L "sp|P63000|RAC1_HUMAN,sp|P15153|RAC2_HUMAN,tr|B1AH77|B1AH77_HUMAN,tr|B1AH78|B1AH78_HUMAN,tr|B1AH80|B1AH80_HUMAN" 5 1485.7885 1.06 98122 10242 3 1485.791113 496.2701 Ras-related C3 botulinum toxin substrate 1 OS=Homo sapiens OX=9606 GN=RAC1 PE=1 SV=1 4.36 2061.8 - 1.20E+06 - - - 1.7533 - 2.393 0.245 - 241.8 1 2 2 0.0026 12 0 0 0 5.16E+07 4.86E+07 - - - 3.6894 0.9908 221125_WJC_METTL3_EV_vs_WT_F07.10243.10243.3 3.02 Dec-44 K.LDLRDDKDTIEK.L "sp|P63000|RAC1_HUMAN,sp|P15153|RAC2_HUMAN,tr|B1AH77|B1AH77_HUMAN,tr|B1AH78|B1AH78_HUMAN,tr|B1AH80|B1AH80_HUMAN" 5 1459.7518 1.04 98123 10243 3 1459.752529 487.5912 Ras-related C3 botulinum toxin substrate 1 OS=Homo sapiens OX=9606 GN=RAC1 PE=1 SV=1 4.36 2061.9 - 1.10E+06 - - - 0.4734 - 2.371 0.17 - 202.7 1 2 2 0.0007 12 0 0 0 5.07E+07 4.86E+07 - - - 2.8281 1 221125_WJC_METTL3_EV_vs_WT_F07.10246.10246.3 7.15E-05 14/36 K.HVLTEDIVHR.E "sp|Q9Y255|PRLD1_HUMAN,tr|D6REW1|D6REW1_HUMAN" 2 1217.6517 2.45 98126 10246 3 1217.652518 406.8912 "PRELI domain-containing protein 1, mitochondrial OS=Homo sapiens OX=9606 GN=PRELID1 PE=1 SV=1" 5.99 2062.3 - 431244 - - - 0.6964 - 2.602 0.477 - 326.7 1 2 0 0.0008 10 0 0 0 5.16E+06 2.11E+06 - - - 6.6506 0.8348 221125_WJC_METTL3_EV_vs_WT_F07.10248.10248.2 0.0345 20-Jul R.NEELK[136.11]EVEEER[166.11].K "sp|Q92878|RAD50_HUMAN,tr|A0A1W2PQ90|A0A1W2PQ90_HUMAN" 2 1420.6801 0.1 98128 10248 2 1420.68853 711.3473 DNA repair protein RAD50 OS=Homo sapiens OX=9606 GN=RAD50 PE=1 SV=1 4.21 2062.5 - 227727 - - - 5.9528 - 1.619 0.373 - 133.7 1 2 1 0.0085 11 0 0 0 2.30E+05 2.37E+06 - - - 3.0967 0.8249 221125_WJC_METTL3_EV_vs_WT_F07.10250.10250.3 0.315 13/48 T.GVFAPRPSTGPHK.L "sp|P62701|RS4X_HUMAN,sp|P22090|RS4Y1_HUMAN,sp|Q8TD47|RS4Y2_HUMAN,tr|C9JEH7|C9JEH7_HUMAN" 4 1349.7204 1.19 98130 10250 3 1349.719704 450.9141 "40S ribosomal protein S4, X isoform OS=Homo sapiens OX=9606 GN=RPS4X PE=1 SV=2" 11 2062.8 - 250644 - - - -0.529 - 1.864 0.233 - 144.7 1 1 0 -0.0007 13 0 0 0 3.11E+06 2.62E+06 - - - 2.8259 1 221125_WJC_METTL3_EV_vs_WT_F07.10251.10251.2 7.29E-11 15/34 K.FGQGVDNAAGQAGNEAGR.F sp|Q6UWP8|SBSN_HUMAN 1 1717.7768 999 98131 10251 2 1717.783447 859.8957 Suprabasin OS=Homo sapiens OX=9606 GN=SBSN PE=1 SV=2 4.37 2062.9 - 159753 - - - 3.8556 - 3.698 0.521 - 607.3 1 2 0 0.0066 18 0 0 0 3.86E+07 0.00E+00 - - - 6.1023 0.9998 221125_WJC_METTL3_EV_vs_WT_F07.10254.10254.3 3.30E-05 16/48 R.GGNRFEPYANPTK.R "sp|P52272|HNRPM_HUMAN,tr|M0R019|M0R019_HUMAN,tr|M0R0Y6|M0R0Y6_HUMAN,tr|M0R0N3|M0R0N3_HUMAN,tr|A0A087X0X3|A0A087X0X3_HUMAN,tr|M0QYQ7|M0QYQ7_HUMAN,tr|M0R2T0|M0R2T0_HUMAN" 7 1449.7001 1.66 98132 10254 3 1449.700176 484.2406 Heterogeneous nuclear ribonucleoprotein M OS=Homo sapiens OX=9606 GN=HNRNPM PE=1 SV=3 8.59 2063.3 - 1.33E+06 - - - 0.0683 - 2.557 0.46 - 397.5 1 2 1 0.0001 13 0 0 0 1.86E+08 1.12E+08 - - - 6.214 0.8998 221125_WJC_METTL3_EV_vs_WT_F07.10255.10255.3 3.12 Jul-40 K.EAKPEDLMDSK.L sp|O95292|VAPB_HUMAN 1 1261.586 0.72 98133 10255 3 1261.586703 421.5359 Vesicle-associated membrane protein-associated protein B\C OS=Homo sapiens OX=9606 GN=VAPB PE=1 SV=3 4.32 2063.4 - 873048 - - - 0.543 - 1.28 0.108 - 71.7 1 2 0 0.0007 11 0 0 0 1.35E+07 1.87E+07 - - - 0.4452 0.9847 221125_WJC_METTL3_EV_vs_WT_F07.10256.10256.4 0.257 Sep-84 K.LITQTFSHHNQLAQK[136.11].T "sp|Q9Y266|NUDC_HUMAN,tr|A0A0A0MSS4|A0A0A0MSS4_HUMAN,tr|A0A0A0MSU9|A0A0A0MSU9_HUMAN" 3 1772.9413 1.58 98134 10256 4 1772.942403 444.2426 Nuclear migration protein nudC OS=Homo sapiens OX=9606 GN=NUDC PE=1 SV=1 8.76 2063.4 - 3.56E+06 - - - 0.6125 - 1.411 0.192 - 50.1 1 2 0 0.0011 15 0 0 0 7.40E+07 4.68E+07 - - - 1.0201 0.9225 221125_WJC_METTL3_EV_vs_WT_F07.10257.10257.3 1.26 Aug-40 K.EAK[136.11]PEDLMDSK[136.11].L sp|O95292|VAPB_HUMAN 1 1277.6144 1.04 98135 10257 3 1277.616113 426.8787 Vesicle-associated membrane protein-associated protein B\C OS=Homo sapiens OX=9606 GN=VAPB PE=1 SV=3 4.32 2063.5 - 918428 - - - 1.3267 - 1.352 0.121 - 91.1 1 2 0 0.0017 11 0 0 0 1.32E+07 1.27E+07 - - - 0.7453 0.9981 221125_WJC_METTL3_EV_vs_WT_F07.10258.10258.3 2.98E-05 Dec-52 T.AGDTHLGGEDFDNR[166.11].L "sp|P48741|HSP77_HUMAN,sp|P54652|HSP72_HUMAN,sp|P0DMV8|HS71A_HUMAN,sp|P34931|HS71L_HUMAN,sp|P11142|HSP7C_HUMAN,sp|P0DMV9|HS71B_HUMAN,sp|P17066|HSP76_HUMAN,tr|E9PKE3|E9PKE3_HUMAN,tr|E9PN89|E9PN89_HUMAN,tr|Q53FA3|Q53FA3_HUMAN,tr|V9GZ37|V9GZ37_HUMAN,tr|A0A0G2JIW1|A0A0G2JIW1_HUMAN" 12 1512.6469 0.23 98136 10258 3 1512.647254 505.2229 Putative heat shock 70 kDa protein 7 OS=Homo sapiens OX=9606 GN=HSPA7 PE=5 SV=2 4.22 2063.6 - 914584 - - - 0.2545 - 2.067 0.601 - 172.6 1 1 0 0.0004 14 0 0 0 3.52E+06 1.54E+07 - - - 7.1701 0.9999 221125_WJC_METTL3_EV_vs_WT_F07.10259.10259.3 4.79E-05 Oct-36 K.K[136.11]LYK[136.11]PEVQLR[166.11].R "sp|O60610|DIAP1_HUMAN,tr|A0A2R8Y5N1|A0A2R8Y5N1_HUMAN,tr|A0A140T8Z0|A0A140T8Z0_HUMAN,tr|A0A0G2JH68|A0A0G2JH68_HUMAN,tr|H9KV28|H9KV28_HUMAN" 5 1298.7921 0.91 98137 10259 3 1298.79396 433.938 Protein diaphanous homolog 1 OS=Homo sapiens OX=9606 GN=DIAPH1 PE=1 SV=2 9.7 2063.7 - 498860 - - - 1.4498 - 2.332 0.418 - 134.3 1 2 0 0.0019 10 0 0 0 7.28E+06 8.01E+06 - - - 5.6726 0.9986 221125_WJC_METTL3_EV_vs_WT_F07.10260.10260.3 0.00803 Nov-40 R.NEELKEVEEER.K "sp|Q92878|RAD50_HUMAN,tr|A0A1W2PQ90|A0A1W2PQ90_HUMAN" 2 1402.6576 0.28 98138 10260 3 1402.657505 468.5598 DNA repair protein RAD50 OS=Homo sapiens OX=9606 GN=RAD50 PE=1 SV=1 4.21 2063.9 - 415755 - - - -0.0699 - 2.088 0.323 - 191.1 1 2 1 -0.0001 11 0 0 0 4.44E+06 1.60E+07 - - - 4.2325 1 221125_WJC_METTL3_EV_vs_WT_F07.10261.10261.2 8.01E-05 15/30 R.LNQSDSIEDPNSPAGR.R sp|Q86VS8|HOOK3_HUMAN 1 1698.7809 15.08 98139 10261 2 1698.783818 850.3977 Protein Hook homolog 3 OS=Homo sapiens OX=9606 GN=HOOK3 PE=1 SV=2 4.03 2064 - 276672 - - - 1.7142 - 2.996 0.629 - 481.3 1 2 0 0.0029 16 0 0 0 1.10E+07 7.28E+05 - - - 6.3836 0.9958 221125_WJC_METTL3_EV_vs_WT_F07.10264.10264.2 0.235 20-May R.R[166.11]DEYGLPSQPK[136.11].Q "sp|Q8IZH2|XRN1_HUMAN,tr|H7C5E4|H7C5E4_HUMAN" 2 1306.6636 1.28 98142 10264 2 1306.665443 654.3391 5'-3' exoribonuclease 1 OS=Homo sapiens OX=9606 GN=XRN1 PE=1 SV=1 6.07 2064.4 - 104813 - - - 1.3837 - 1.278 0.254 - 95.3 1 2 0 0.0018 11 0 0 0 8.09E+06 6.31E+06 - - - 1.5801 0.9996 221125_WJC_METTL3_EV_vs_WT_F07.10267.10267.3 0.000177 16/48 R.GGNR[166.11]FEPYANPTK[136.11].R "sp|P52272|HNRPM_HUMAN,tr|M0R019|M0R019_HUMAN,tr|M0R0Y6|M0R0Y6_HUMAN,tr|M0R0N3|M0R0N3_HUMAN,tr|A0A087X0X3|A0A087X0X3_HUMAN,tr|M0QYQ7|M0QYQ7_HUMAN,tr|M0R2T0|M0R2T0_HUMAN" 7 1467.7225 1.65 98143 10267 3 1467.725793 490.2481 Heterogeneous nuclear ribonucleoprotein M OS=Homo sapiens OX=9606 GN=HNRNPM PE=1 SV=3 8.59 2064.8 - 2.29E+06 - - - 2.2116 - 2.389 0.474 - 426.1 1 2 1 0.0032 13 0 0 0 1.86E+08 1.13E+08 - - - 6.1849 1 221125_WJC_METTL3_EV_vs_WT_F07.10269.10269.3 1.13E-07 Nov-56 K.SEDSSGAAGLSGLHR.T "sp|Q86U86|PB1_HUMAN,tr|H0Y5B5|H0Y5B5_HUMAN,tr|E7EVG2|E7EVG2_HUMAN" 3 1442.675 2.27 98145 10269 3 1442.676295 481.8989 Protein polybromo-1 OS=Homo sapiens OX=9606 GN=PBRM1 PE=1 SV=1 5.3 2064.9 - 1.62E+06 - - - 0.9087 - 2.984 0.588 - 138.1 1 2 0 0.0013 15 0 0 0 1.66E+07 7.32E+06 - - - 7.948 0.9998 221125_WJC_METTL3_EV_vs_WT_F07.10270.10270.2 2.27E-05 26-Dec R.SLLEGEGSSGGGGR.G "sp|P13645|K1C10_HUMAN,tr|A0A1B0GVI3|A0A1B0GVI3_HUMAN" 2 1261.5899 999 98146 10270 2 1261.590064 631.8022 "Keratin, type I cytoskeletal 10 OS=Homo sapiens OX=9606 GN=KRT10 PE=1 SV=6" 4.53 2065 - 1.25E+06 - - - 0.1633 - 2.317 0.434 - 423.2 1 2 0 0.0002 14 0 0 0 2.10E+07 0.00E+00 - - - 4.3551 0.9975 221125_WJC_METTL3_EV_vs_WT_F07.10271.10271.3 0.0311 Oct-48 K.QIANEIPVSSNR[166.11]R[166.11].D "sp|Q8IZH2|XRN1_HUMAN,tr|H7C5E4|H7C5E4_HUMAN" 2 1502.8068 8.23 98147 10271 3 1502.808989 501.9429 5'-3' exoribonuclease 1 OS=Homo sapiens OX=9606 GN=XRN1 PE=1 SV=1 9.6 2065.1 - 657106 - - - 1.4373 - 1.916 0.233 - 153.4 1 2 0 0.0022 13 0 0 0 4.97E+07 6.04E+06 - - - 2.9001 0.8925 221125_WJC_METTL3_EV_vs_WT_F07.10273.10273.3 0.278 Aug-52 R.HGGAGGSPSVTWAR.A "sp|Q9NZM4|BICRA_HUMAN,tr|A0A087WWH3|A0A087WWH3_HUMAN" 2 1338.6429 1.33 98149 10273 3 1338.638152 447.2216 BRD4-interacting chromatin-remodeling complex-associated protein OS=Homo sapiens OX=9606 GN=BICRA PE=1 SV=2 9.76 2065.3 - 513462 - - - -3.5439 - 1.169 0.216 - 43.7 1 2 0 -0.0047 14 0 0 0 5.48E+06 4.12E+06 - - - 1.3618 0.993 221125_WJC_METTL3_EV_vs_WT_F07.10274.10274.3 0.00185 Oct-44 R.LR[166.11]AEPDHMVLGK[136.11].R "sp|P41252|SYIC_HUMAN,tr|A0A804HL54|A0A804HL54_HUMAN,tr|A0A804HIV9|A0A804HIV9_HUMAN,tr|A0A804HJN6|A0A804HJN6_HUMAN,tr|A0A804HHW9|A0A804HHW9_HUMAN,tr|A0A0A0MSX9|A0A0A0MSX9_HUMAN,tr|J3KR24|J3KR24_HUMAN,tr|A0A804HJ36|A0A804HJ36_HUMAN" 8 1382.7459 1.9 98150 10274 3 1382.74536 461.9226 "Isoleucine--tRNA ligase, cytoplasmic OS=Homo sapiens OX=9606 GN=IARS1 PE=1 SV=2" 6.75 2065.4 - 448250 - - - -0.4086 - 1.914 0.24 - 143.8 1 2 1 -0.0006 12 0 0 0 5.83E+06 3.07E+06 - - - 3.0151 0.9842 221125_WJC_METTL3_EV_vs_WT_F07.10276.10276.2 0.00478 24-Dec T.GVFAPRPSTGPHK.L "sp|P62701|RS4X_HUMAN,sp|P22090|RS4Y1_HUMAN,sp|Q8TD47|RS4Y2_HUMAN,tr|C9JEH7|C9JEH7_HUMAN" 4 1349.7204 1.34 98152 10276 2 1349.721169 675.8675 "40S ribosomal protein S4, X isoform OS=Homo sapiens OX=9606 GN=RPS4X PE=1 SV=2" 11 2065.6 - 275016 - - - 0.5564 - 1.912 0.425 - 251.6 1 1 0 0.0008 13 0 0 0 2.43E+06 1.82E+06 - - - 3.8433 1 221125_WJC_METTL3_EV_vs_WT_F07.10278.10278.2 3.25E-07 13/24 R.DQTPDENDQVVVK.L sp|O00425|IF2B3_HUMAN 1 1485.6947 1.66 98154 10278 2 1485.698808 743.8546 Insulin-like growth factor 2 mRNA-binding protein 3 OS=Homo sapiens OX=9606 GN=IGF2BP3 PE=1 SV=2 3.84 2065.9 - 197318 - - - 2.7536 - 2.391 0.609 - 534.9 1 2 0 0.0041 13 0 0 0 4.71E+07 2.84E+07 - - - 5.7751 0.9997 221125_WJC_METTL3_EV_vs_WT_F07.10279.10279.2 5.01E-07 24-Oct R.DQTPDENDQVVVK[136.11].L sp|O00425|IF2B3_HUMAN 1 1493.7089 1.66 98155 10279 2 1493.712855 747.8617 Insulin-like growth factor 2 mRNA-binding protein 3 OS=Homo sapiens OX=9606 GN=IGF2BP3 PE=1 SV=2 3.84 2066 - 176689 - - - 2.6364 - 2.163 0.59 - 267.5 1 2 0 0.0039 13 0 0 0 4.69E+07 2.83E+07 - - - 5.3776 0.9994 221125_WJC_METTL3_EV_vs_WT_F07.10280.10280.2 0.00712 28-Aug K.LITQTFSHHNQLAQK.T "sp|Q9Y266|NUDC_HUMAN,tr|A0A0A0MSS4|A0A0A0MSS4_HUMAN,tr|A0A0A0MSU9|A0A0A0MSU9_HUMAN" 3 1764.9271 4.12 98156 10280 2 1764.928111 883.4708 Nuclear migration protein nudC OS=Homo sapiens OX=9606 GN=NUDC PE=1 SV=1 8.76 2066.2 - 119019 - - - 0.5632 - 1.569 0.372 - 143.2 1 2 0 0.001 15 0 0 0 1.48E+06 3.60E+05 - - - 2.8957 0.9998 221125_WJC_METTL3_EV_vs_WT_F07.10283.10283.3 1.97E-05 13/40 R.SESHTDLTFSR[166.11].E sp|O15226|NKRF_HUMAN 1 1288.5923 0.89 98157 10283 3 1288.595588 430.538 NF-kappa-B-repressing factor OS=Homo sapiens OX=9606 GN=NKRF PE=1 SV=2 5.3 2066.6 - 1.13E+06 - - - 2.5408 - 2.467 0.41 - 315.4 1 2 0 0.0033 11 0 0 0 3.25E+07 3.64E+07 - - - 5.6755 1 221125_WJC_METTL3_EV_vs_WT_F07.10284.10284.3 2.10E-07 17/56 R.QAVTNPNNTFYATK[136.11]R[166.11].L "sp|P38646|GRP75_HUMAN,tr|H0Y8K0|H0Y8K0_HUMAN,tr|A0A7I2V2S7|A0A7I2V2S7_HUMAN,tr|A0A7I2V2G2|A0A7I2V2G2_HUMAN,tr|A0A3B3ITI4|A0A3B3ITI4_HUMAN,tr|A0A7I2V3F7|A0A7I2V3F7_HUMAN,tr|A0A7I2YQB2|A0A7I2YQB2_HUMAN,tr|D6RCD7|D6RCD7_HUMAN" 8 1741.8867 1.2 98158 10284 3 1741.887807 581.6362 "Stress-70 protein, mitochondrial OS=Homo sapiens OX=9606 GN=HSPA9 PE=1 SV=2" 9.99 2066.7 - 713842 - - - 0.6631 - 3.167 0.51 - 579.2 1 2 0 0.0012 15 0 0 0 4.95E+07 4.13E+07 - - - 7.2337 1 221125_WJC_METTL3_EV_vs_WT_F07.10285.10285.3 6.34E-09 17/68 K.FGQGVDNAAGQAGNEAGR.F sp|Q6UWP8|SBSN_HUMAN 1 1717.7768 439.37 98159 10285 3 1717.778637 573.5996 Suprabasin OS=Homo sapiens OX=9606 GN=SBSN PE=1 SV=2 4.37 2066.8 - 2.38E+06 - - - 1.0554 - 2.666 0.603 - 322.2 1 2 0 0.0018 18 0 0 0 2.24E+07 5.09E+04 - - - 7.7041 0.9923 221125_WJC_METTL3_EV_vs_WT_F07.10287.10287.2 0.00314 24-Nov R.GGNRFEPYANPTK.R "sp|P52272|HNRPM_HUMAN,tr|M0R019|M0R019_HUMAN,tr|M0R0Y6|M0R0Y6_HUMAN,tr|M0R0N3|M0R0N3_HUMAN,tr|A0A087X0X3|A0A087X0X3_HUMAN,tr|M0QYQ7|M0QYQ7_HUMAN,tr|M0R2T0|M0R2T0_HUMAN" 7 1449.7001 2 98161 10287 2 1449.70136 725.8573 Heterogeneous nuclear ribonucleoprotein M OS=Homo sapiens OX=9606 GN=HNRNPM PE=1 SV=3 8.59 2067 - 505387 - - - 0.885 - 2.161 0.258 - 382.1 1 2 1 0.0013 13 0 0 0 1.44E+07 7.17E+06 - - - 2.9239 0.9998 221125_WJC_METTL3_EV_vs_WT_F07.10288.10288.2 3.18E-05 20-Oct R.VEIIANDQGNR[166.11].L "sp|P11021|BIP_HUMAN,sp|P48741|HSP77_HUMAN,sp|P54652|HSP72_HUMAN,sp|P0DMV8|HS71A_HUMAN,sp|P34931|HS71L_HUMAN,sp|P11142|HSP7C_HUMAN,sp|P0DMV9|HS71B_HUMAN,sp|P17066|HSP76_HUMAN,tr|E9PQQ4|E9PQQ4_HUMAN,tr|E9PNE6|E9PNE6_HUMAN,tr|E9PKE3|E9PKE3_HUMAN,tr|A0A7P0TB36|A0A7P0TB36_HUMAN,tr|E9PLF4|E9PLF4_HUMAN,tr|A0A7P0TAI0|A0A7P0TAI0_HUMAN,tr|Q53FA3|Q53FA3_HUMAN,tr|E9PI65|E9PI65_HUMAN,tr|E9PK54|E9PK54_HUMAN,tr|E9PN25|E9PN25_HUMAN,tr|E9PPY6|E9PPY6_HUMAN,tr|E9PQK7|E9PQK7_HUMAN,tr|A0A0G2JIW1|A0A0G2JIW1_HUMAN" 21 1237.629 0.17 98162 10288 2 1237.629709 619.8218 Endoplasmic reticulum chaperone BiP OS=Homo sapiens OX=9606 GN=HSPA5 PE=1 SV=2 4.37 2067.1 - 492113 - - - 0.5454 - 2.265 0.45 - 298.7 1 2 0 0.0007 11 0 0 0 4.74E+06 2.79E+07 - - - 4.5762 0.9988 221125_WJC_METTL3_EV_vs_WT_F07.10289.10289.3 0.00865 Oct-40 R.R[166.11]DEYGLPSQPK[136.11].Q "sp|Q8IZH2|XRN1_HUMAN,tr|H7C5E4|H7C5E4_HUMAN" 2 1306.6636 1.28 98163 10289 3 1306.664887 436.5618 5'-3' exoribonuclease 1 OS=Homo sapiens OX=9606 GN=XRN1 PE=1 SV=1 6.07 2067.3 - 392679 - - - 0.9582 - 1.94 0.254 - 178.6 1 2 0 0.0013 11 0 0 0 1.96E+07 1.53E+07 - - - 3.2541 0.9949 221125_WJC_METTL3_EV_vs_WT_F07.10291.10291.2 0.0155 24-Sep R.GGNR[166.11]FEPYANPTK[136.11].R "sp|P52272|HNRPM_HUMAN,tr|M0R019|M0R019_HUMAN,tr|M0R0Y6|M0R0Y6_HUMAN,tr|M0R0N3|M0R0N3_HUMAN,tr|A0A087X0X3|A0A087X0X3_HUMAN,tr|M0QYQ7|M0QYQ7_HUMAN,tr|M0R2T0|M0R2T0_HUMAN" 7 1467.7225 2 98165 10291 2 1467.724155 734.8685 Heterogeneous nuclear ribonucleoprotein M OS=Homo sapiens OX=9606 GN=HNRNPM PE=1 SV=3 8.59 2067.5 - 331872 - - - 1.0956 - 1.838 0.388 - 279.2 1 2 1 0.0016 13 0 0 0 1.44E+07 7.17E+06 - - - 3.4685 0.9998 221125_WJC_METTL3_EV_vs_WT_F07.10293.10293.2 0.0239 13/22 K.NQNSWGTGEDVK[136.11].V sp|P20700|LMNB1_HUMAN 1 1341.6041 1.22 98167 10293 2 1341.60651 671.8093 Lamin-B1 OS=Homo sapiens OX=9606 GN=LMNB1 PE=1 SV=2 4.37 2067.8 - 305512 - - - 1.8277 - 2.522 0.473 - 700.3 1 2 0 0.0025 12 0 0 0 1.63E+07 1.33E+07 - - - 4.9678 0.9997 221125_WJC_METTL3_EV_vs_WT_F07.10296.10296.2 8.33E-07 Sep-32 R.LVAGEMGQNEPDQGGQR[166.11].G "sp|Q99714|HCD2_HUMAN,tr|Q5H928|Q5H928_HUMAN,tr|A0A804HHW5|A0A804HHW5_HUMAN" 3 1794.8194 0.48 98170 10296 2 1794.814877 898.417 3-hydroxyacyl-CoA dehydrogenase type-2 OS=Homo sapiens OX=9606 GN=HSD17B10 PE=1 SV=3 4.14 2068.2 - 146591 - - - -2.5367 - 2.184 0.589 - 201.4 1 2 0 -0.0046 17 0 0 0 1.38E+06 2.88E+06 - - - 5.3104 1 221125_WJC_METTL3_EV_vs_WT_F07.10299.10299.3 7.46E-05 Nov-40 R.SESHTDLTFSR.E sp|O15226|NKRF_HUMAN 1 1278.584 0.89 98171 10299 3 1278.585671 427.202 NF-kappa-B-repressing factor OS=Homo sapiens OX=9606 GN=NKRF PE=1 SV=2 5.3 2068.6 - 2.02E+06 - - - 1.2725 - 2.354 0.473 - 323.2 1 2 0 0.0016 11 0 0 0 3.25E+07 3.64E+07 - - - 6.2451 0.9993 221125_WJC_METTL3_EV_vs_WT_F07.10301.10301.3 0.615 Dec-32 K.NIHLNLDRR.T "sp|Q9Y5S9|RBM8A_HUMAN,tr|A0A0J9YW13|A0A0J9YW13_HUMAN" 2 1149.6367 1.52 98173 10301 3 1149.636585 384.2195 RNA-binding protein 8A OS=Homo sapiens OX=9606 GN=RBM8A PE=1 SV=1 9.61 2068.7 - 2.53E+06 - - - -0.0905 - 2.016 0.26 - 277.5 1 2 0 -0.0001 9 0 0 0 7.34E+07 4.82E+07 - - - 3.5517 1 221125_WJC_METTL3_EV_vs_WT_F07.10303.10303.2 4.13E-07 22-Dec K.NQNSWGTGEDVK.V sp|P20700|LMNB1_HUMAN 1 1333.5899 1.22 98175 10303 2 1333.589617 667.8022 Lamin-B1 OS=Homo sapiens OX=9606 GN=LMNB1 PE=1 SV=2 4.37 2068.9 - 951371 - - - -0.1807 - 2.824 0.624 - 572.1 1 2 0 -0.0002 12 0 0 0 1.63E+07 1.33E+07 - - - 6.3813 0.999 221125_WJC_METTL3_EV_vs_WT_F07.10305.10305.4 0.000712 Nov-90 R.TIQRPVTMGDEGGLRR.L "sp|Q14527|HLTF_HUMAN,tr|H7C5K0|H7C5K0_HUMAN,tr|A0A0C4DGA6|A0A0C4DGA6_HUMAN" 3 1784.9316 1.03 98177 10305 4 1784.931791 447.2402 Helicase-like transcription factor OS=Homo sapiens OX=9606 GN=HLTF PE=1 SV=2 9.17 2069.1 - 625331 - - - 0.135 - 2.056 0.296 - 77 1 2 0 0.0002 16 0 0 0 3.98E+06 3.87E+06 - - - 2.0562 0.9864 221125_WJC_METTL3_EV_vs_WT_F07.10308.10308.2 0.00315 20-Aug R.SESHTDLTFSR[166.11].E sp|O15226|NKRF_HUMAN 1 1288.5923 1.19 98180 10308 2 1288.590761 645.3034 NF-kappa-B-repressing factor OS=Homo sapiens OX=9606 GN=NKRF PE=1 SV=2 5.3 2069.4 - 338890 - - - -1.2052 - 1.437 0.078 - 146.5 1 2 0 -0.0016 11 0 0 0 6.21E+06 5.23E+06 - - - 0.5974 0.9997 221125_WJC_METTL3_EV_vs_WT_F07.10309.10309.3 0.000446 Nov-52 R.MQEGEGHSQLC[160.03]LDR[166.11].L "sp|Q8WUA4|TF3C2_HUMAN,tr|H0Y4Q6|H0Y4Q6_HUMAN,tr|H7C1A9|H7C1A9_HUMAN,tr|H7C318|H7C318_HUMAN" 4 1668.7224 0.65 98181 10309 3 1668.725683 557.2481 General transcription factor 3C polypeptide 2 OS=Homo sapiens OX=9606 GN=GTF3C2 PE=1 SV=2 4.65 2069.5 - 319607 - - - 1.9919 - 1.649 0.437 - 166.4 1 2 0 0.0033 14 0 0 0 1.25E+06 1.92E+06 - - - 4.7404 1 221125_WJC_METTL3_EV_vs_WT_F07.10310.10310.3 2.13E-05 15/56 K.AHNNELEPTPGNTLR.Q "sp|P24928|RPB1_HUMAN,tr|A0A6Q8PGB0|A0A6Q8PGB0_HUMAN" 2 1661.8121 1.93 98182 10310 3 1661.810602 554.9447 DNA-directed RNA polymerase II subunit RPB1 OS=Homo sapiens OX=9606 GN=POLR2A PE=1 SV=2 5.4 2069.6 - 261671 - - - -0.9297 - 3.057 0.495 - 326.5 1 2 0 -0.0015 15 0 0 0 2.28E+07 1.18E+07 - - - 6.9741 0.9879 221125_WJC_METTL3_EV_vs_WT_F07.10311.10311.3 2.82E-06 14/84 F.ASSLVSGLNSSASEPAK[136.11]EPAK[136.11]K[136.11].S "sp|Q86U44|MTA70_HUMAN,tr|F5H6D8|F5H6D8_HUMAN,tr|H0YFV6|H0YFV6_HUMAN,tr|B4DTN4|B4DTN4_HUMAN" 4 2181.1703 0.001 98183 10311 3 2181.169289 728.0641 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 8.54 2069.8 - 260199 - - - -0.4759 - 2.573 0.533 - 148 1 1 1 -0.001 22 0 0 0 0.00E+00 2.06E+06 - - - 6.7227 0.9994 221125_WJC_METTL3_EV_vs_WT_F07.10313.10313.2 4.45E-06 28-Sep K.SQAPGQPGASQWGSR.V "sp|Q96EP5|DAZP1_HUMAN,tr|K7EK33|K7EK33_HUMAN,tr|K7EQ55|K7EQ55_HUMAN,tr|K7EQ02|K7EQ02_HUMAN" 4 1512.707 1.36 98185 10313 2 1512.711405 757.3608 DAZ-associated protein 1 OS=Homo sapiens OX=9606 GN=DAZAP1 PE=1 SV=1 9.47 2070 - 154416 - - - 2.9431 - 1.822 0.58 - 156.5 1 2 0 0.0045 15 0 0 0 2.58E+07 1.89E+07 - - - 4.7984 0.9992 221125_WJC_METTL3_EV_vs_WT_F07.10318.10318.3 0.214 Nov-32 K.NIHLNLDR[166.11]R[166.11].T "sp|Q9Y5S9|RBM8A_HUMAN,tr|A0A0J9YW13|A0A0J9YW13_HUMAN" 2 1169.6532 1.52 98188 10318 3 1169.652989 390.8917 RNA-binding protein 8A OS=Homo sapiens OX=9606 GN=RBM8A PE=1 SV=1 9.61 2070.6 - 4.95E+06 - - - -0.2052 - 1.806 0.283 - 257.1 1 2 0 -0.0002 9 0 0 0 7.34E+07 4.82E+07 - - - 3.4766 1 221125_WJC_METTL3_EV_vs_WT_F07.10319.10319.3 4.88E-05 13/40 R.DGWGGYGSDK[136.11]R[166.11].L "sp|Q14151|SAFB2_HUMAN,sp|Q15424|SAFB1_HUMAN" 2 1214.5435 1.32 98189 10319 3 1214.543666 405.8551 Scaffold attachment factor B2 OS=Homo sapiens OX=9606 GN=SAFB2 PE=1 SV=1 5.96 2070.7 - 2.03E+06 - - - 0.1202 - 2.471 0.512 - 253.2 1 2 0 0.0001 11 0 0 0 3.29E+07 2.48E+07 - - - 6.8181 0.8715 221125_WJC_METTL3_EV_vs_WT_F07.10320.10320.3 0.0358 Oct-44 K.DLVIER[166.11]PR[166.11]PDSR[166.11].P "sp|Q9Y520|PRC2C_HUMAN,tr|E7EPN9|E7EPN9_HUMAN" 2 1481.8093 1.21 98190 10320 3 1481.810418 494.9437 Protein PRRC2C OS=Homo sapiens OX=9606 GN=PRRC2C PE=1 SV=4 6.12 2070.8 - 2.18E+06 - - - 0.7646 - 1.685 0.277 - 120.5 1 1 0 0.0011 12 0 0 0 2.67E+07 2.20E+07 - - - 3.0742 0.9987 221125_WJC_METTL3_EV_vs_WT_F07.10321.10321.3 0.000273 Oct-48 K.ELR[166.11]DEEQTAESIK[136.11].N sp|Q14566|MCM6_HUMAN 1 1564.77 0.85 98191 10321 3 1564.770263 522.5973 DNA replication licensing factor MCM6 OS=Homo sapiens OX=9606 GN=MCM6 PE=1 SV=1 4.25 2070.8 - 1.10E+06 - - - 0.1994 - 2.044 0.342 - 217.4 1 2 1 0.0003 13 0 0 0 6.27E+06 7.38E+06 - - - 4.2912 0.9994 221125_WJC_METTL3_EV_vs_WT_F07.10325.10325.2 8.30E-05 13/20 R.SESHTDLTFSR.E sp|O15226|NKRF_HUMAN 1 1278.584 0.96 98195 10325 2 1278.579713 640.2993 NF-kappa-B-repressing factor OS=Homo sapiens OX=9606 GN=NKRF PE=1 SV=2 5.3 2071.2 - 567452 - - - -3.3873 - 2.309 0.518 - 672.6 1 2 0 -0.0043 11 0 0 0 4.79E+06 4.99E+06 - - - 5.1294 0.9998 221125_WJC_METTL3_EV_vs_WT_F07.10327.10327.3 7.70E-05 13/56 K.AHNNELEPTPGNTLR[166.11].Q "sp|P24928|RPB1_HUMAN,tr|A0A6Q8PGB0|A0A6Q8PGB0_HUMAN" 2 1671.8204 2.94 98197 10327 3 1671.824512 558.2807 DNA-directed RNA polymerase II subunit RPB1 OS=Homo sapiens OX=9606 GN=POLR2A PE=1 SV=2 5.4 2071.4 - 456214 - - - 2.4494 - 2.458 0.431 - 230.8 1 2 0 0.0041 15 0 0 0 3.64E+07 1.24E+07 - - - 5.6908 0.9998 221125_WJC_METTL3_EV_vs_WT_F07.10328.10328.2 0.0151 20-Nov R.VEIIANDQGNR.L "sp|P11021|BIP_HUMAN,sp|P48741|HSP77_HUMAN,sp|P54652|HSP72_HUMAN,sp|P0DMV8|HS71A_HUMAN,sp|P34931|HS71L_HUMAN,sp|P11142|HSP7C_HUMAN,sp|P0DMV9|HS71B_HUMAN,sp|P17066|HSP76_HUMAN,tr|E9PQQ4|E9PQQ4_HUMAN,tr|E9PNE6|E9PNE6_HUMAN,tr|E9PKE3|E9PKE3_HUMAN,tr|A0A7P0TB36|A0A7P0TB36_HUMAN,tr|E9PLF4|E9PLF4_HUMAN,tr|A0A7P0TAI0|A0A7P0TAI0_HUMAN,tr|Q53FA3|Q53FA3_HUMAN,tr|E9PI65|E9PI65_HUMAN,tr|E9PK54|E9PK54_HUMAN,tr|E9PN25|E9PN25_HUMAN,tr|E9PPY6|E9PPY6_HUMAN,tr|E9PQK7|E9PQK7_HUMAN,tr|A0A0G2JIW1|A0A0G2JIW1_HUMAN" 21 1227.6208 0.17 98198 10328 2 1227.621913 614.8177 Endoplasmic reticulum chaperone BiP OS=Homo sapiens OX=9606 GN=HSPA5 PE=1 SV=2 4.37 2071.6 - 455281 - - - 0.936 - 2.253 0.392 - 451.6 1 2 0 0.0011 11 0 0 0 4.74E+06 2.79E+07 - - - 4.1333 0.9909 221125_WJC_METTL3_EV_vs_WT_F07.10329.10329.4 0.00932 Nov-90 R.TIQR[166.11]PVTMGDEGGLR[166.11]R[166.11].L "sp|Q14527|HLTF_HUMAN,tr|H7C5K0|H7C5K0_HUMAN,tr|A0A0C4DGA6|A0A0C4DGA6_HUMAN" 3 1814.9564 1.29 98199 10329 4 1814.956522 454.7464 Helicase-like transcription factor OS=Homo sapiens OX=9606 GN=HLTF PE=1 SV=2 9.17 2071.7 - 448447 - - - 0.0893 - 1.949 0.2 - 81.7 1 2 0 0.0002 16 0 0 0 5.07E+06 3.94E+06 - - - 1.2018 0.9999 221125_WJC_METTL3_EV_vs_WT_F07.10330.10330.2 1.69E-05 20-Aug R.DGWGGYGSDK[136.11]R[166.11].L "sp|Q14151|SAFB2_HUMAN,sp|Q15424|SAFB1_HUMAN" 2 1214.5435 1.24 98200 10330 2 1214.542897 608.279 Scaffold attachment factor B2 OS=Homo sapiens OX=9606 GN=SAFB2 PE=1 SV=1 5.96 2071.8 - 388537 - - - -0.5129 - 1.746 0.591 - 141.9 1 2 0 -0.0006 11 0 0 0 6.22E+06 5.01E+06 - - - 4.9136 0.9994 221125_WJC_METTL3_EV_vs_WT_F07.10332.10332.3 0.000174 14/48 K.VVTKPGHIINPIK.A sp|Q9BVJ6|UT14A_HUMAN 1 1414.866 1.79 98202 10332 3 1414.869989 472.6293 U3 small nucleolar RNA-associated protein 14 homolog A OS=Homo sapiens OX=9606 GN=UTP14A PE=1 SV=1 10 2072.1 - 325771 - - - 2.8052 - 2.344 0.345 - 177.8 1 2 0 0.004 13 0 0 0 1.88E+07 1.05E+07 - - - 4.6949 0.9972 221125_WJC_METTL3_EV_vs_WT_F07.10333.10333.2 2.30E-08 15/28 K.INNLNVEENSSGDQR.R sp|Q9Y5V3|MAGD1_HUMAN 1 1687.7762 1.07 98203 10333 2 1687.785152 844.8954 Melanoma-associated antigen D1 OS=Homo sapiens OX=9606 GN=MAGED1 PE=1 SV=3 4.14 2072.2 - 290024 - - - 5.3307 - 3.159 0.42 - 781.3 1 2 0 0.009 15 0 0 0 8.09E+06 7.53E+06 - - - 4.9683 0.9998 221125_WJC_METTL3_EV_vs_WT_F07.10338.10338.3 1.80E-05 Nov-48 K.ELRDEEQTAESIK.N sp|Q14566|MCM6_HUMAN 1 1546.7475 0.84 98206 10338 3 1546.746475 516.5898 DNA replication licensing factor MCM6 OS=Homo sapiens OX=9606 GN=MCM6 PE=1 SV=1 4.25 2072.9 - 1.40E+06 - - - -0.6504 - 2.339 0.465 - 256.1 1 2 1 -0.001 13 0 0 0 6.18E+06 7.38E+06 - - - 6.0279 0.9999 221125_WJC_METTL3_EV_vs_WT_F07.10339.10339.2 0.000365 20-Oct R.DSYDSYATHNE.- sp|Q14011|CIRBP_HUMAN 1 1300.4844 - 98207 10339 2 1300.485584 651.2495 Cold-inducible RNA-binding protein OS=Homo sapiens OX=9606 GN=CIRBP PE=1 SV=1 4.31 2073 - 1.06E+06 - - - 0.9181 - 1.834 0.584 - 224 1 2 0 0.0012 11 0 0 0 - - - - - 4.9948 0.9995 221125_WJC_METTL3_EV_vs_WT_F07.10340.10340.3 0.00664 Nov-36 K.EISTPTHWSK.L "sp|Q8IX12|CCAR1_HUMAN,tr|F5H2E6|F5H2E6_HUMAN,tr|F5H1H2|F5H1H2_HUMAN,tr|A0A0C4DGG8|A0A0C4DGG8_HUMAN" 4 1184.5826 5.35 98208 10340 3 1184.583249 395.8681 Cell division cycle and apoptosis regulator protein 1 OS=Homo sapiens OX=9606 GN=CCAR1 PE=1 SV=2 6.85 2073.1 - 918495 - - - 0.558 - 1.771 0.318 - 135.3 1 2 0 0.0007 10 0 0 0 1.33E+07 2.49E+06 - - - 3.7544 1 221125_WJC_METTL3_EV_vs_WT_F07.10341.10341.2 6.18E-09 16/28 K.SQAPGQPGASQWGSR[166.11].V "sp|Q96EP5|DAZP1_HUMAN,tr|K7EK33|K7EK33_HUMAN,tr|K7EQ55|K7EQ55_HUMAN,tr|K7EQ02|K7EQ02_HUMAN" 4 1522.7152 1.36 98209 10341 2 1522.716468 762.3649 DAZ-associated protein 1 OS=Homo sapiens OX=9606 GN=DAZAP1 PE=1 SV=1 9.47 2073.2 - 736504 - - - 0.8176 - 2.672 0.638 - 542.5 1 2 0 0.0012 15 0 0 0 2.57E+07 1.89E+07 - - - 6.1692 1 221125_WJC_METTL3_EV_vs_WT_F07.10342.10342.3 0.000585 15/48 K.GHTSFVNSC[160.03]YPAR.R sp|Q96DI7|SNR40_HUMAN 1 1494.6674 1.66 98210 10342 3 1494.667434 499.2297 U5 small nuclear ribonucleoprotein 40 kDa protein OS=Homo sapiens OX=9606 GN=SNRNP40 PE=1 SV=1 8.23 2073.4 - 580350 - - - 0.0248 - 2.817 0.542 - 419.3 1 2 0 0 13 0 0 0 6.10E+07 3.67E+07 - - - 7.3908 0.9834 221125_WJC_METTL3_EV_vs_WT_F07.10343.10343.3 0.127 Sep-36 K.EKTQMITINR.D "sp|Q8IX12|CCAR1_HUMAN,tr|H0YFJ7|H0YFJ7_HUMAN,tr|A0A0C4DGG8|A0A0C4DGG8_HUMAN" 3 1232.6547 0.87 98211 10343 3 1232.654993 411.8922 Cell division cycle and apoptosis regulator protein 1 OS=Homo sapiens OX=9606 GN=CCAR1 PE=1 SV=2 8.85 2073.5 - 536322 - - - 0.232 - 1.358 0.269 - 109.1 1 2 1 0.0003 10 0 0 0 2.84E+06 3.28E+06 - - - 2.4327 1 221125_WJC_METTL3_EV_vs_WT_F07.10345.10345.2 4.16E-09 26-Dec S.LQC[160.03]YNC[160.03]PNPTADC[160.03]K.T "sp|P13987|CD59_HUMAN,tr|A0A499FJN7|A0A499FJN7_HUMAN,tr|A0A494C059|A0A494C059_HUMAN,tr|E9PNW4|E9PNW4_HUMAN,tr|A0A2U3TZL5|A0A2U3TZL5_HUMAN,tr|E9PI80|E9PI80_HUMAN" 6 1739.7066 1.76 98213 10345 2 1739.709316 870.8606 CD59 glycoprotein OS=Homo sapiens OX=9606 GN=CD59 PE=1 SV=1 5.81 2073.8 - 425174 - - - 1.5836 - 2.846 0.702 - 496.6 1 1 0 0.0028 14 0 0 0 8.44E+06 4.78E+06 - - - 6.8498 0.9998 221125_WJC_METTL3_EV_vs_WT_F07.10348.10348.3 1.34E-05 14/56 K.SQAPGQPGASQWGSR.V "sp|Q96EP5|DAZP1_HUMAN,tr|K7EK33|K7EK33_HUMAN,tr|K7EQ55|K7EQ55_HUMAN,tr|K7EQ02|K7EQ02_HUMAN" 4 1512.707 0.64 98216 10348 3 1512.712261 505.2429 DAZ-associated protein 1 OS=Homo sapiens OX=9606 GN=DAZAP1 PE=1 SV=1 9.47 2074.1 - 326365 - - - 3.5089 - 2.463 0.481 - 249.9 1 2 0 0.0053 15 0 0 0 8.42E+06 1.31E+07 - - - 6.2532 0.997 221125_WJC_METTL3_EV_vs_WT_F07.10350.10350.2 0.0221 28-May K.NDVLAHQATVETVNK.A "sp|Q9UPN3|MACF1_HUMAN,tr|A0A804HL78|A0A804HL78_HUMAN,tr|H3BQK9|H3BQK9_HUMAN,tr|A0A7P0MQR8|A0A7P0MQR8_HUMAN,tr|H0Y390|H0Y390_HUMAN,tr|H3BPE1|H3BPE1_HUMAN,tr|A0A590UJG2|A0A590UJG2_HUMAN" 7 1637.8373 -1 98218 10350 2 1637.83793 819.9259 "Microtubule-actin cross-linking factor 1, isoforms 1\2\3\5 OS=Homo sapiens OX=9606 GN=MACF1 PE=1 SV=4" 5.32 2074.4 - 110629 - - - 0.3853 - 1.125 0.298 - 80.3 1 2 0 0.0006 15 0 0 0 0.00E+00 0.00E+00 - - - 1.5314 1 221125_WJC_METTL3_EV_vs_WT_F07.10351.10351.2 6.52E-09 13/30 R.VAGTQAC[160.03]ATETIDTSR.V sp|Q9BRR6|ADPGK_HUMAN 1 1679.7785 0.7 98219 10351 2 1679.780122 840.8965 ADP-dependent glucokinase OS=Homo sapiens OX=9606 GN=ADPGK PE=1 SV=1 4.37 2074.5 - 103722 - - - 0.987 - 2.392 0.629 - 482.4 1 2 0 0.0017 16 0 0 0 4.16E+06 5.98E+06 - - - 5.8304 0.7724 221125_WJC_METTL3_EV_vs_WT_F07.10356.10356.2 0.108 14/18 K.QR[166.11]YPDGIISK[136.11].P sp|Q86U44|MTA70_HUMAN 1 1193.6523 0.03 98222 10356 2 1193.653247 597.8334 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 8.59 2075.1 - 2.30E+06 - - - 0.7582 - 2.506 0.236 - 695.4 1 1 1 0.0009 10 0 0 0 1.23E+06 4.05E+07 - - - 3.3481 0.9984 221125_WJC_METTL3_EV_vs_WT_F07.10358.10358.3 0.0297 Nov-52 K.QIATLHAQVADMK[136.11]K[136.11].K sp|P35579|MYH9_HUMAN 1 1568.8679 0.85 98224 10358 3 1568.871121 523.9633 Myosin-9 OS=Homo sapiens OX=9606 GN=MYH9 PE=1 SV=4 8.6 2075.3 - 1.09E+06 - - - 2.0231 - 2.209 0.251 - 110.4 1 2 0 0.0032 14 0 0 0 6.36E+06 7.49E+06 - - - 3.4437 0.9998 221125_WJC_METTL3_EV_vs_WT_F07.10359.10359.3 0.000147 16/52 K.QIATLHAQVADMKK.K sp|P35579|MYH9_HUMAN 1 1552.8395 0.85 98225 10359 3 1552.843855 518.6205 Myosin-9 OS=Homo sapiens OX=9606 GN=MYH9 PE=1 SV=4 8.6 2075.3 - 923953 - - - 2.7743 - 2.678 0.423 - 275.1 1 2 0 0.0043 14 0 0 0 6.36E+06 7.49E+06 - - - 5.8727 0.9999 221125_WJC_METTL3_EV_vs_WT_F07.10360.10360.2 6.88E-08 24-Dec K.SSSSTNTSLLTSK[136.11].S sp|Q9NXV6|CARF_HUMAN 1 1319.666 0.87 98226 10360 2 1319.666593 660.8403 CDKN2A-interacting protein OS=Homo sapiens OX=9606 GN=CDKN2AIP PE=1 SV=3 8.47 2075.4 - 577717 - - - 0.4577 - 2.346 0.542 - 460.6 1 2 0 0.0006 13 0 0 0 5.76E+06 6.62E+06 - - - 5.2325 0.9994 221125_WJC_METTL3_EV_vs_WT_F07.10361.10361.2 0.00368 20-Sep R.RDEYGLPSQPK.Q "sp|Q8IZH2|XRN1_HUMAN,tr|H7C5E4|H7C5E4_HUMAN" 2 1288.6412 1.27 98227 10361 2 1288.64253 645.3279 5'-3' exoribonuclease 1 OS=Homo sapiens OX=9606 GN=XRN1 PE=1 SV=1 6.07 2075.6 - 575652 - - - 1.0593 - 1.782 0.35 - 239.1 1 2 0 0.0014 11 0 0 0 7.99E+06 6.31E+06 - - - 3.1886 0.9999 221125_WJC_METTL3_EV_vs_WT_F07.10362.10362.2 2.28E-05 13/24 K.SSSSTNTSLLTSK.S sp|Q9NXV6|CARF_HUMAN 1 1311.6518 0.87 98228 10362 2 1311.652394 656.8332 CDKN2A-interacting protein OS=Homo sapiens OX=9606 GN=CDKN2AIP PE=1 SV=3 8.47 2075.7 - 560142 - - - 0.4613 - 2.47 0.508 - 457.4 1 2 0 0.0006 13 0 0 0 5.76E+06 6.62E+06 - - - 5.1136 0.9999 221125_WJC_METTL3_EV_vs_WT_F07.10363.10363.3 0.000164 14/52 R.DVLETEDEEPPPRR.W "sp|Q9ULV3|CIZ1_HUMAN,tr|Q5SYW2|Q5SYW2_HUMAN,tr|F5H2X7|F5H2X7_HUMAN,tr|H0Y5D5|H0Y5D5_HUMAN,tr|A0A0U1RQR2|A0A0U1RQR2_HUMAN,tr|A0A494C0L7|A0A494C0L7_HUMAN,tr|Q9BTG3|Q9BTG3_HUMAN" 7 1680.7955 3.11 98229 10363 3 1680.791882 561.2724 Cip1-interacting zinc finger protein OS=Homo sapiens OX=9606 GN=CIZ1 PE=1 SV=2 4.08 2075.8 - 495365 - - - -2.149 - 2.434 0.46 - 273.8 1 2 0 -0.0036 14 0 0 0 5.56E+07 1.79E+07 - - - 6.0315 1 221125_WJC_METTL3_EV_vs_WT_F07.10364.10364.2 9.12E-08 15/26 S.LQC[160.03]YNC[160.03]PNPTADC[160.03]K[136.11].T "sp|P13987|CD59_HUMAN,tr|A0A499FJN7|A0A499FJN7_HUMAN,tr|A0A494C059|A0A494C059_HUMAN,tr|E9PNW4|E9PNW4_HUMAN,tr|A0A2U3TZL5|A0A2U3TZL5_HUMAN,tr|E9PI80|E9PI80_HUMAN" 6 1747.7208 1.76 98230 10364 2 1747.722157 874.8677 CD59 glycoprotein OS=Homo sapiens OX=9606 GN=CD59 PE=1 SV=1 5.81 2076 - 493427 - - - 0.7988 - 2.916 0.696 - 924.9 1 1 0 0.0014 14 0 0 0 8.44E+06 4.78E+06 - - - 6.8669 0.9999 221125_WJC_METTL3_EV_vs_WT_F07.10365.10365.2 1.55E-06 26-Nov R.LQQQQQQQQLAQMK.L "sp|Q6Y7W6|GGYF2_HUMAN,tr|A0A7I2V3H7|A0A7I2V3H7_HUMAN,tr|I1E4Y6|I1E4Y6_HUMAN,tr|A0A7I2V516|A0A7I2V516_HUMAN,tr|A0A7I2V3H0|A0A7I2V3H0_HUMAN,tr|A0A7I2V361|A0A7I2V361_HUMAN" 6 1726.8785 2.35 98231 10365 2 1726.880079 864.4465 GRB10-interacting GYF protein 2 OS=Homo sapiens OX=9606 GN=GIGYF2 PE=1 SV=1 8.75 2076.1 - 458499 - - - 0.9422 - 2.488 0.503 - 391.6 1 2 0 0.0016 14 0 0 0 1.48E+07 6.30E+06 - - - 5.043 0.9987 221125_WJC_METTL3_EV_vs_WT_F07.10366.10366.3 0.000139 Dec-56 K.INNLNVEENSSGDQR.R sp|Q9Y5V3|MAGD1_HUMAN 1 1687.7762 2.26 98232 10366 3 1687.780323 563.5993 Melanoma-associated antigen D1 OS=Homo sapiens OX=9606 GN=MAGED1 PE=1 SV=3 4.14 2076.2 - 409424 - - - 2.4695 - 1.803 0.339 - 155 1 2 0 0.0042 15 0 0 0 3.19E+06 1.41E+06 - - - 3.8565 1 221125_WJC_METTL3_EV_vs_WT_F07.10368.10368.2 4.63E-10 15/38 K.SYLSGGAGAAGGGGADPGNK.K "sp|P25490|TYY1_HUMAN,tr|H0YJU4|H0YJU4_HUMAN,tr|H0YJV7|H0YJV7_HUMAN" 3 1662.7598 0.94 98234 10368 2 1662.754606 832.3872 Transcriptional repressor protein YY1 OS=Homo sapiens OX=9606 GN=YY1 PE=1 SV=2 5.55 2076.5 - 380365 - - - -3.1099 - 2.797 0.681 - 342.3 1 2 0 -0.0052 20 0 0 0 3.23E+06 3.45E+06 - - - 6.598 1 221125_WJC_METTL3_EV_vs_WT_F07.10370.10370.2 5.05E-11 17/38 K.SYLSGGAGAAGGGGADPGNK[136.11].K "sp|P25490|TYY1_HUMAN,tr|H0YJU4|H0YJU4_HUMAN,tr|H0YJV7|H0YJV7_HUMAN" 3 1670.774 0.94 98236 10370 2 1670.777327 836.3943 Transcriptional repressor protein YY1 OS=Homo sapiens OX=9606 GN=YY1 PE=1 SV=2 5.55 2076.7 - 335854 - - - 2.0051 - 3.239 0.688 - 442.5 1 2 0 0.0034 20 0 0 0 3.23E+06 3.45E+06 - - - 7.011 0.9999 221125_WJC_METTL3_EV_vs_WT_F07.10371.10371.2 5.47E-06 13/26 R.ETANAIVSQQTPQR.L "sp|P40938|RFC3_HUMAN,tr|A0A087X270|A0A087X270_HUMAN" 2 1541.7798 1 98237 10371 2 1541.77962 771.8972 Replication factor C subunit 3 OS=Homo sapiens OX=9606 GN=RFC3 PE=1 SV=2 6.1 2076.9 - 227424 - - - -0.1064 - 2.412 0.544 - 452.3 1 2 0 -0.0002 14 0 0 0 7.60E+06 7.56E+06 - - - 5.2684 0.999 221125_WJC_METTL3_EV_vs_WT_F07.10374.10374.2 4.73E-07 14/26 R.ETANAIVSQQTPQR[166.11].L "sp|P40938|RFC3_HUMAN,tr|A0A087X270|A0A087X270_HUMAN" 2 1551.7881 1 98240 10374 2 1551.781586 776.9013 Replication factor C subunit 3 OS=Homo sapiens OX=9606 GN=RFC3 PE=1 SV=2 6.1 2077.3 - 179183 - - - -4.1681 - 2.669 0.534 - 628.2 1 2 0 -0.0065 14 0 0 0 7.60E+06 7.56E+06 - - - 5.4466 0.9976 221125_WJC_METTL3_EV_vs_WT_F07.10377.10377.3 0.048 Oct-48 K.SIIQSAQQDSIK[136.11]K[136.11].A sp|Q92616|GCN1_HUMAN 1 1460.817 1 98241 10377 3 1460.818719 487.9463 eIF-2-alpha kinase activator GCN1 OS=Homo sapiens OX=9606 GN=GCN1 PE=1 SV=6 8.31 2077.7 - 2.50E+06 - - - 1.2055 - 1.858 0.235 - 72.7 1 2 0 0.0018 13 0 0 0 2.01E+07 2.00E+07 - - - 2.8392 0.9998 221125_WJC_METTL3_EV_vs_WT_F07.10378.10378.3 2.66E-07 14/56 R.K[136.11]PALVSTVEGGQDPK[136.11].N "sp|Q14690|RRP5_HUMAN,tr|A0A3B3IUD7|A0A3B3IUD7_HUMAN" 2 1540.8432 0.86 98242 10378 3 1540.848859 514.6217 Protein RRP5 homolog OS=Homo sapiens OX=9606 GN=PDCD11 PE=1 SV=3 6.07 2077.8 - 1.46E+06 - - - 3.6908 - 2.309 0.514 - 223.6 1 2 0 0.0057 15 0 0 0 9.42E+06 1.10E+07 - - - 6.4526 0.9999 221125_WJC_METTL3_EV_vs_WT_F07.10380.10380.3 3.83E-05 17/44 K.HLVGGLHTVYTK.L "sp|Q9UI36|DACH1_HUMAN,sp|Q96NX9|DACH2_HUMAN,tr|D6RFG7|D6RFG7_HUMAN,tr|D6REJ4|D6REJ4_HUMAN" 4 1323.7299 1.71 98244 10380 3 1323.733818 442.2506 Dachshund homolog 1 OS=Homo sapiens OX=9606 GN=DACH1 PE=1 SV=4 8.61 2078 - 929858 - - - 2.9447 - 2.835 0.462 - 258.9 1 2 0 0.0039 12 0 0 0 1.03E+07 5.98E+06 - - - 6.5781 0.9999 221125_WJC_METTL3_EV_vs_WT_F07.10383.10383.2 1.74E-07 13/30 R.VAGTQAC[160.03]ATETIDTSR[166.11].V sp|Q9BRR6|ADPGK_HUMAN 1 1689.7867 0.7 98247 10383 2 1689.787387 845.9006 ADP-dependent glucokinase OS=Homo sapiens OX=9606 GN=ADPGK PE=1 SV=1 4.37 2078.4 - 549559 - - - 0.3864 - 2.947 0.468 - 631 1 2 0 0.0007 16 0 0 0 4.16E+06 5.98E+06 - - - 5.1546 1 221125_WJC_METTL3_EV_vs_WT_F07.10384.10384.3 2.49E-06 17/52 R.DHAVVVGVYRPPPK.V sp|P22087|FBRL_HUMAN 1 1532.8463 0.93 98248 10384 3 1532.847888 511.9561 rRNA 2'-O-methyltransferase fibrillarin OS=Homo sapiens OX=9606 GN=FBL PE=1 SV=2 8.6 2078.4 - 456556 - - - 1.0053 - 2.786 0.448 - 440.5 1 2 0 0.0015 14 0 0 0 2.25E+08 2.42E+08 - - - 6.2573 0.7818 221125_WJC_METTL3_EV_vs_WT_F07.10385.10385.3 0.178 Jul-40 K.WK[136.11]PGSLASHVK[136.11].N "sp|P06493|CDK1_HUMAN,tr|A0A024QZP7|A0A024QZP7_HUMAN" 2 1224.695 1.12 98249 10385 3 1224.699914 409.2389 Cyclin-dependent kinase 1 OS=Homo sapiens OX=9606 GN=CDK1 PE=1 SV=3 10 2078.6 - 416370 - - - 4.019 - 1.428 0.178 - 43.7 9 2 0 0.0049 11 0 0 0 3.43E+06 3.07E+06 - - - 1.0936 0.9349 221125_WJC_METTL3_EV_vs_WT_F07.10386.10386.3 1.01 Oct-56 K.NDVLAHQATVETVNK.A "sp|Q9UPN3|MACF1_HUMAN,tr|A0A804HL78|A0A804HL78_HUMAN,tr|H3BQK9|H3BQK9_HUMAN,tr|A0A7P0MQR8|A0A7P0MQR8_HUMAN,tr|H0Y390|H0Y390_HUMAN,tr|H3BPE1|H3BPE1_HUMAN,tr|A0A590UJG2|A0A590UJG2_HUMAN" 7 1637.8373 0.77 98250 10386 3 1637.839524 546.953 "Microtubule-actin cross-linking factor 1, isoforms 1\2\3\5 OS=Homo sapiens OX=9606 GN=MACF1 PE=1 SV=4" 5.32 2078.7 - 408089 - - - 1.3585 - 1.666 0.101 - 69.8 2 2 0 0.0022 15 0 0 0 6.65E+06 8.67E+06 - - - 0.858 0.905 221125_WJC_METTL3_EV_vs_WT_F07.10389.10389.2 0.961 18-Jun K.EISTPTHWSK.L "sp|Q8IX12|CCAR1_HUMAN,tr|F5H2E6|F5H2E6_HUMAN,tr|F5H1H2|F5H1H2_HUMAN,tr|A0A0C4DGG8|A0A0C4DGG8_HUMAN" 4 1184.5826 0.24 98253 10389 2 1184.586481 593.2986 Cell division cycle and apoptosis regulator protein 1 OS=Homo sapiens OX=9606 GN=CCAR1 PE=1 SV=2 6.85 2079.1 - 297169 - - - 3.2864 - 1.264 0.1 - 95.1 3 2 0 0.0039 10 0 0 0 2.43E+06 1.03E+07 - - - 0.2192 0.9992 221125_WJC_METTL3_EV_vs_WT_F07.10392.10392.2 3.61E-05 22-Aug K.NDEC[160.03]VLEDNSQR.T "sp|Q9UPN3|MACF1_HUMAN,tr|H3BQK9|H3BQK9_HUMAN,tr|A0A7P0MQR8|A0A7P0MQR8_HUMAN,tr|E9PNZ4|E9PNZ4_HUMAN,tr|H0Y390|H0Y390_HUMAN,tr|E9PLY5|E9PLY5_HUMAN,tr|H3BPE1|H3BPE1_HUMAN,tr|A0A669KBB0|A0A669KBB0_HUMAN,tr|A0A590UJG2|A0A590UJG2_HUMAN,tr|A0A5F9ZGX0|A0A5F9ZGX0_HUMAN" 10 1477.6103 3.11 98255 10392 2 1477.615757 739.8124 "Microtubule-actin cross-linking factor 1, isoforms 1\2\3\5 OS=Homo sapiens OX=9606 GN=MACF1 PE=1 SV=4" 3.92 2079.5 - 150261 - - - 3.6688 - 1.694 0.637 - 234.5 1 2 0 0.0054 12 0 0 0 1.32E+06 4.25E+05 - - - 5.1311 1 221125_WJC_METTL3_EV_vs_WT_F07.10395.10395.3 6.50E-08 14/48 K.VDNDENEHQLSLR[166.11].T "sp|P06748|NPM_HUMAN,tr|A0A7I2V4G8|A0A7I2V4G8_HUMAN,tr|A0A7I2YQC0|A0A7I2YQC0_HUMAN,tr|A0A7I2V433|A0A7I2V433_HUMAN,tr|A0A7I2V579|A0A7I2V579_HUMAN,tr|A0A7I2V2X9|A0A7I2V2X9_HUMAN,tr|A0A7I2V3G5|A0A7I2V3G5_HUMAN,tr|A0A7I2V5S2|A0A7I2V5S2_HUMAN,tr|A0A7I2V3U2|A0A7I2V3U2_HUMAN,tr|E5RGW4|E5RGW4_HUMAN" 10 1577.7309 0.77 98257 10395 3 1577.734355 526.9176 Nucleophosmin OS=Homo sapiens OX=9606 GN=NPM1 PE=1 SV=2 4.31 2079.8 - 783275 - - - 2.1689 - 3.029 0.596 - 418 1 2 0 0.0034 13 0 0 0 2.08E+07 2.71E+07 - - - 8.1886 0.9996 221125_WJC_METTL3_EV_vs_WT_F07.10397.10397.3 7.23E-07 15/44 K.KPHIYYGSLEEK.E sp|O43172|PRP4_HUMAN 1 1462.7456 3.04 98259 10397 3 1462.749226 488.5892 U4\U6 small nuclear ribonucleoprotein Prp4 OS=Homo sapiens OX=9606 GN=PRPF4 PE=1 SV=2 6.75 2080 - 4.62E+06 - - - 2.4584 - 2.564 0.334 - 272.6 1 2 0 0.0036 12 0 0 0 6.45E+07 2.12E+07 - - - 4.8727 1 221125_WJC_METTL3_EV_vs_WT_F07.10398.10398.3 1.71E-07 14/48 K.SIIQSAQQDSIKK.A sp|Q92616|GCN1_HUMAN 1 1444.7886 1 98260 10398 3 1444.792198 482.6035 eIF-2-alpha kinase activator GCN1 OS=Homo sapiens OX=9606 GN=GCN1 PE=1 SV=6 8.31 2080.1 - 3.14E+06 - - - 2.5194 - 2.909 0.535 - 176.8 1 2 0 0.0036 13 0 0 0 2.05E+07 2.06E+07 - - - 7.3989 0.9999 221125_WJC_METTL3_EV_vs_WT_F07.10399.10399.3 1.24E-06 18/60 R.IAEC[160.03]SSQLAEEEEK[136.11]AK[136.11].N sp|P35580|MYH10_HUMAN 1 1836.8746 0.99 98261 10399 3 1836.876383 613.2988 Myosin-10 OS=Homo sapiens OX=9606 GN=MYH10 PE=1 SV=3 4.33 2080.2 - 948753 - - - 0.9658 - 3.356 0.537 - 512.5 1 2 1 0.0018 16 0 0 0 2.99E+07 3.02E+07 - - - 7.6331 0.9998 221125_WJC_METTL3_EV_vs_WT_F07.10400.10400.3 7.51E-06 17/48 K.VVTK[136.11]PGHIINPIK[136.11].A sp|Q9BVJ6|UT14A_HUMAN 1 1430.8944 1.77 98262 10400 3 1430.897575 477.9721 U3 small nucleolar RNA-associated protein 14 homolog A OS=Homo sapiens OX=9606 GN=UTP14A PE=1 SV=1 10 2080.3 - 932720 - - - 2.2049 - 2.962 0.366 - 235.7 1 2 0 0.0032 13 0 0 0 1.86E+07 1.05E+07 - - - 5.5638 0.9994 221125_WJC_METTL3_EV_vs_WT_F07.10401.10401.3 1.14E-05 Nov-56 R.VASVFANADKGDDEK.N "sp|Q86U86|PB1_HUMAN,tr|H0Y5B5|H0Y5B5_HUMAN,tr|E7EVG2|E7EVG2_HUMAN" 3 1564.7369 1.6 98263 10401 3 1564.738242 522.5862 Protein polybromo-1 OS=Homo sapiens OX=9606 GN=PBRM1 PE=1 SV=1 4.23 2080.3 - 854446 - - - 0.8474 - 2.26 0.384 - 154.4 1 2 1 0.0013 15 0 0 0 4.49E+06 2.80E+06 - - - 4.9484 1 221125_WJC_METTL3_EV_vs_WT_F07.10404.10404.3 1.32E-06 16/44 K.HLVGGLHTVYTK[136.11].L "sp|Q9UI36|DACH1_HUMAN,sp|Q96NX9|DACH2_HUMAN,tr|D6RFG7|D6RFG7_HUMAN,tr|D6REJ4|D6REJ4_HUMAN" 4 1331.7441 1.77 98266 10404 3 1331.746389 444.922 Dachshund homolog 1 OS=Homo sapiens OX=9606 GN=DACH1 PE=1 SV=4 8.61 2080.6 - 607221 - - - 1.7038 - 2.631 0.502 - 248.6 1 2 0 0.0023 12 0 0 0 1.07E+07 6.01E+06 - - - 6.8176 1 221125_WJC_METTL3_EV_vs_WT_F07.10405.10405.3 4.87E-11 23/60 R.IAEC[160.03]SSQLAEEEEKAK.N sp|P35580|MYH10_HUMAN 1 1820.8462 0.99 98267 10405 3 1820.853451 607.956 Myosin-10 OS=Homo sapiens OX=9606 GN=MYH10 PE=1 SV=3 4.33 2080.8 - 552329 - - - 3.9773 - 3.74 0.622 - 952.4 1 2 1 0.0072 16 0 0 0 2.99E+07 3.02E+07 - - - 8.8573 0.9994 221125_WJC_METTL3_EV_vs_WT_F07.10408.10408.2 0.000831 24-Nov K.SIIQSAQQDSIK[136.11]K[136.11].A sp|Q92616|GCN1_HUMAN 1 1460.817 1.18 98270 10408 2 1460.821276 731.4158 eIF-2-alpha kinase activator GCN1 OS=Homo sapiens OX=9606 GN=GCN1 PE=1 SV=6 8.31 2081.1 - 181897 - - - 2.9559 - 2.359 0.472 - 388.4 1 2 0 0.0043 13 0 0 0 1.43E+06 1.21E+06 - - - 4.7285 1 221125_WJC_METTL3_EV_vs_WT_F07.10412.10412.2 1.10E-09 28-Dec R.SDSPVPTAPTSGGPK[136.11].P "sp|Q86U44|MTA70_HUMAN,tr|B4E349|B4E349_HUMAN,tr|F5H6D8|F5H6D8_HUMAN,tr|B4DTN4|B4DTN4_HUMAN" 4 1404.6976 0.001 98273 10412 2 1404.698679 703.3561 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 5.55 2081.7 - 629914 - - - 0.7511 - 2.469 0.636 - 279.4 1 1 0 0.0011 15 0 0 0 0.00E+00 1.52E+07 - - - 5.9602 0.9857 221125_WJC_METTL3_EV_vs_WT_F07.10415.10415.4 0.0121 Sep-72 R.LYK[136.11]EELEQTYHAK[136.11].L "sp|P20700|LMNB1_HUMAN,tr|E9PBF6|E9PBF6_HUMAN,tr|A0A0D9SFE5|A0A0D9SFE5_HUMAN" 3 1666.8537 1.15 98275 10415 4 1666.856002 417.7207 Lamin-B1 OS=Homo sapiens OX=9606 GN=LMNB1 PE=1 SV=2 5.5 2082 - 2.27E+06 - - - 1.3588 - 1.792 0.244 - 62.3 1 2 1 0.0023 13 0 0 0 6.94E+07 6.04E+07 - - - 1.5654 0.9975 221125_WJC_METTL3_EV_vs_WT_F07.10417.10417.3 0.0241 Sep-56 R.KPALVSTVEGGQDPK.N "sp|Q14690|RRP5_HUMAN,tr|A0A3B3IUD7|A0A3B3IUD7_HUMAN" 2 1524.8148 0.84 98277 10417 3 1524.818327 509.2789 Protein RRP5 homolog OS=Homo sapiens OX=9606 GN=PDCD11 PE=1 SV=3 6.07 2082.1 - 1.15E+06 - - - 2.3314 - 1.661 0.306 - 90.2 1 2 0 0.0036 15 0 0 0 9.24E+06 1.10E+07 - - - 3.2747 0.9997 221125_WJC_METTL3_EV_vs_WT_F07.10419.10419.3 0.000704 13/56 R.EAETFK[136.11]EQGNAYYAK[136.11].K "sp|Q99615|DNJC7_HUMAN,tr|K7ESP1|K7ESP1_HUMAN,tr|A0A6I8PR89|A0A6I8PR89_HUMAN,tr|A0A6I8PIK4|A0A6I8PIK4_HUMAN,tr|K7ELJ8|K7ELJ8_HUMAN,tr|A0A6I8PS32|A0A6I8PS32_HUMAN,tr|A0A6I8PUD4|A0A6I8PUD4_HUMAN,tr|K7EIH8|K7EIH8_HUMAN,tr|A0A6I8PU73|A0A6I8PU73_HUMAN,tr|K7EK03|K7EK03_HUMAN,tr|A0A6I8PU89|A0A6I8PU89_HUMAN" 11 1763.8337 0.63 98279 10419 3 1763.836229 588.9519 DnaJ homolog subfamily C member 7 OS=Homo sapiens OX=9606 GN=DNAJC7 PE=1 SV=2 4.79 2082.4 - 425610 - - - 1.4168 - 2.186 0.488 - 181.8 1 2 1 0.0025 15 0 0 0 8.67E+06 1.39E+07 - - - 6.0207 0.9557 221125_WJC_METTL3_EV_vs_WT_F07.10420.10420.3 0.624 Aug-40 K.WKPGSLASHVK.N "sp|P06493|CDK1_HUMAN,tr|A0A024QZP7|A0A024QZP7_HUMAN" 2 1208.6666 1.09 98280 10420 3 1208.670168 403.8961 Cyclin-dependent kinase 1 OS=Homo sapiens OX=9606 GN=CDK1 PE=1 SV=3 10 2082.5 - 222877 - - - 2.9586 - 1.458 0.186 - 70.5 1 2 0 0.0036 11 0 0 0 3.59E+06 3.29E+06 - - - 1.6839 0.9988 221125_WJC_METTL3_EV_vs_WT_F07.10421.10421.2 5.50E-05 22-Oct K.KPHIYYGSLEEK.E sp|O43172|PRP4_HUMAN 1 1462.7456 4.22 98281 10421 2 1462.749921 732.3801 U4\U6 small nuclear ribonucleoprotein Prp4 OS=Homo sapiens OX=9606 GN=PRPF4 PE=1 SV=2 6.75 2082.6 - 213825 - - - 2.9335 - 2.151 0.351 - 409 1 2 0 0.0043 12 0 0 0 1.85E+06 4.39E+05 - - - 3.6474 1 221125_WJC_METTL3_EV_vs_WT_F07.10428.10428.3 2.45E-05 15/48 K.QEYDESGPSIVHR.K "sp|Q6S8J3|POTEE_HUMAN,sp|P63261|ACTG_HUMAN,sp|Q9BYX7|ACTBM_HUMAN,sp|P60709|ACTB_HUMAN,sp|A5A3E0|POTEF_HUMAN,sp|P0CG38|POTEI_HUMAN,sp|P0CG39|POTEJ_HUMAN,tr|A0A2R8YFE2|A0A2R8YFE2_HUMAN,tr|A0A804GS07|A0A804GS07_HUMAN,tr|A0A6Q8PFE4|A0A6Q8PFE4_HUMAN,tr|I3L4N8|I3L4N8_HUMAN" 11 1515.6954 1.04 98286 10428 3 1515.699884 506.2391 POTE ankyrin domain family member E OS=Homo sapiens OX=9606 GN=POTEE PE=2 SV=3 4.65 2083.6 - 2.01E+06 - - - 2.9676 - 2.85 0.606 - 356.6 1 2 0 0.0045 13 0 0 0 7.99E+08 7.69E+08 - - - 8.1346 1 221125_WJC_METTL3_EV_vs_WT_F07.10429.10429.3 7.33E-05 13/44 R.DNPK[136.11]PNVSEALR[166.11].S sp|P82909|RT36_HUMAN 1 1356.7116 1.99 98287 10429 3 1356.71255 453.2445 "28S ribosomal protein S36, mitochondrial OS=Homo sapiens OX=9606 GN=MRPS36 PE=1 SV=2" 6.07 2083.7 - 898914 - - - 0.6648 - 2.483 0.464 - 262.1 1 2 0 0.0009 12 0 0 0 9.90E+07 4.98E+07 - - - 6.2338 0.9995 221125_WJC_METTL3_EV_vs_WT_F07.10430.10430.3 3.94E-08 15/48 R.LYK[136.11]EELEQTYHAK[136.11].L "sp|P20700|LMNB1_HUMAN,tr|E9PBF6|E9PBF6_HUMAN,tr|A0A0D9SFE5|A0A0D9SFE5_HUMAN" 3 1666.8537 1.25 98288 10430 3 1666.858605 556.6252 Lamin-B1 OS=Homo sapiens OX=9606 GN=LMNB1 PE=1 SV=2 5.5 2083.7 - 3.27E+06 - - - 2.9205 - 2.864 0.452 - 262 1 2 1 0.0049 13 0 0 0 6.30E+07 5.06E+07 - - - 6.4309 0.9999 221125_WJC_METTL3_EV_vs_WT_F07.10432.10432.3 4.63E-07 14/56 R.EAETFKEQGNAYYAK.K "sp|Q99615|DNJC7_HUMAN,tr|K7ESP1|K7ESP1_HUMAN,tr|A0A6I8PR89|A0A6I8PR89_HUMAN,tr|A0A6I8PIK4|A0A6I8PIK4_HUMAN,tr|K7ELJ8|K7ELJ8_HUMAN,tr|A0A6I8PS32|A0A6I8PS32_HUMAN,tr|A0A6I8PUD4|A0A6I8PUD4_HUMAN,tr|K7EIH8|K7EIH8_HUMAN,tr|A0A6I8PU73|A0A6I8PU73_HUMAN,tr|K7EK03|K7EK03_HUMAN,tr|A0A6I8PU89|A0A6I8PU89_HUMAN" 11 1747.8053 0.62 98290 10432 3 1747.806481 583.6091 DnaJ homolog subfamily C member 7 OS=Homo sapiens OX=9606 GN=DNAJC7 PE=1 SV=2 4.79 2083.9 - 477080 - - - 0.6585 - 2.688 0.587 - 238.1 1 2 1 0.0012 15 0 0 0 8.67E+06 1.40E+07 - - - 7.6643 0.996 221125_WJC_METTL3_EV_vs_WT_F07.10433.10433.3 0.0287 Oct-44 R.KFSPSQVPVQTR.S sp|Q9P1Y5|CAMP3_HUMAN 1 1372.7463 1.47 98291 10433 3 1372.74677 458.5894 Calmodulin-regulated spectrin-associated protein 3 OS=Homo sapiens OX=9606 GN=CAMSAP3 PE=1 SV=2 11 2084 - 407812 - - - 0.3431 - 1.724 0.208 - 124 1 2 0 0.0005 12 0 0 0 7.55E+06 5.13E+06 - - - 2.3685 0.9974 221125_WJC_METTL3_EV_vs_WT_F07.10434.10434.2 0.00142 18-Sep R.RQLDNIVGER.G sp|P04259|K2C6B_HUMAN 1 1198.6418 999 98292 10434 2 1198.64648 600.3282 "Keratin, type II cytoskeletal 6B OS=Homo sapiens OX=9606 GN=KRT6B PE=1 SV=5" 6.07 2084.2 - 257012 - - - 3.8761 - 2.106 0.331 - 127.1 1 2 0 0.0046 10 0 0 0 2.26E+06 0.00E+00 - - - 3.5632 0.995 221125_WJC_METTL3_EV_vs_WT_F07.10435.10435.2 0.136 22-Jun R.DNPKPNVSEALR.S sp|P82909|RT36_HUMAN 1 1338.6892 2.48 98293 10435 2 1338.691017 670.3519 "28S ribosomal protein S36, mitochondrial OS=Homo sapiens OX=9606 GN=MRPS36 PE=1 SV=2" 6.07 2084.3 - 128940 - - - 1.3737 - 1.165 0.272 - 73.8 1 2 0 0.0018 12 0 0 0 1.24E+07 5.00E+06 - - - 1.4512 0.9918 221125_WJC_METTL3_EV_vs_WT_F07.10437.10437.2 0.00612 May-32 R.LPPNTNDEVDEDPTGNK.A sp|Q15393|SF3B3_HUMAN 1 1853.8279 1.6 98295 10437 2 1853.834495 927.9212 Splicing factor 3B subunit 3 OS=Homo sapiens OX=9606 GN=SF3B3 PE=1 SV=4 3.77 2084.6 - 114793 - - - 3.5489 - 0.912 0.46 - 46.8 1 2 0 0.0066 17 0 0 0 4.80E+06 3.01E+06 - - - 2.21 1 221125_WJC_METTL3_EV_vs_WT_F07.10439.10439.3 1.05E-05 16/44 K.K[136.11]PHIYYGSLEEK[136.11].E sp|O43172|PRP4_HUMAN 1 1478.774 3.1 98296 10439 3 1478.776006 493.932 U4\U6 small nuclear ribonucleoprotein Prp4 OS=Homo sapiens OX=9606 GN=PRPF4 PE=1 SV=2 6.75 2084.8 - 1.74E+06 - - - 1.3362 - 2.698 0.472 - 277.6 1 2 0 0.002 12 0 0 0 6.45E+07 2.08E+07 - - - 6.5529 0.9832 221125_WJC_METTL3_EV_vs_WT_F07.10445.10445.3 0.000233 13/48 A.ANTFTITGHAETK[136.11].Q "sp|P20290|BTF3_HUMAN,tr|A0A7I2V3T6|A0A7I2V3T6_HUMAN,tr|D6RDG3|D6RDG3_HUMAN,tr|A0A7I2V5Y3|A0A7I2V5Y3_HUMAN,tr|H0Y9Y1|H0Y9Y1_HUMAN,tr|A0A7I2YQL2|A0A7I2YQL2_HUMAN" 6 1397.703 0.8 98301 10445 3 1397.706007 466.9083 Transcription factor BTF3 OS=Homo sapiens OX=9606 GN=BTF3 PE=1 SV=1 6.79 2085.5 - 518195 - - - 2.1199 - 2.445 0.402 - 236.1 1 1 0 0.003 13 0 0 0 4.75E+06 5.97E+06 - - - 5.4451 0.9997 221125_WJC_METTL3_EV_vs_WT_F07.10447.10447.4 0.226 17/78 R.DHAVVVGVYR[166.11]PPPK[136.11].V sp|P22087|FBRL_HUMAN 1 1550.8688 0.88 98303 10447 4 1550.871285 388.7245 rRNA 2'-O-methyltransferase fibrillarin OS=Homo sapiens OX=9606 GN=FBL PE=1 SV=2 8.6 2085.8 - 341136 - - - 1.5914 - 3.066 0.354 - 290.4 1 2 0 0.0025 14 0 0 0 8.57E+07 9.70E+07 - - - 2.7143 0.9995 221125_WJC_METTL3_EV_vs_WT_F07.10448.10448.4 0.011 Dec-78 R.DHAVVVGVYRPPPK.V sp|P22087|FBRL_HUMAN 1 1532.8463 0.87 98304 10448 4 1532.848155 384.2189 rRNA 2'-O-methyltransferase fibrillarin OS=Homo sapiens OX=9606 GN=FBL PE=1 SV=2 8.6 2085.9 - 304752 - - - 1.1795 - 2.172 0.331 - 129.1 1 2 0 0.0018 14 0 0 0 8.39E+07 9.64E+07 - - - 2.3888 0.9997 221125_WJC_METTL3_EV_vs_WT_F07.10449.10449.2 0.00198 18-Sep R.TNQELQEINR.V "sp|P07355|ANXA2_HUMAN,sp|A6NMY6|AXA2L_HUMAN,tr|H0YL33|H0YL33_HUMAN,tr|H0YMU9|H0YMU9_HUMAN,tr|H0YNA0|H0YNA0_HUMAN,tr|H0YMM1|H0YMM1_HUMAN,tr|H0YM50|H0YM50_HUMAN,tr|H0YMD0|H0YMD0_HUMAN,tr|H0YMW4|H0YMW4_HUMAN,tr|H0YLE2|H0YLE2_HUMAN,tr|H0YN42|H0YN42_HUMAN,tr|H0YN28|H0YN28_HUMAN,tr|A0A7I2V4P4|A0A7I2V4P4_HUMAN,tr|H0YNP5|H0YNP5_HUMAN,tr|H0YNB8|H0YNB8_HUMAN,tr|H0YKS4|H0YKS4_HUMAN" 16 1243.6157 999 98305 10449 2 1243.616471 622.8151 Annexin A2 OS=Homo sapiens OX=9606 GN=ANXA2 PE=1 SV=2 4.53 2086 - 170694 - - - 0.6369 - 2.024 0.374 - 333.2 1 2 0 0.0008 10 0 0 0 1.49E+06 0.00E+00 - - - 3.7712 0.9969 221125_WJC_METTL3_EV_vs_WT_F07.10452.10452.2 0.000555 24-Sep R.LYKEELEQTYHAK.L "sp|P20700|LMNB1_HUMAN,tr|E9PBF6|E9PBF6_HUMAN,tr|A0A0D9SFE5|A0A0D9SFE5_HUMAN" 3 1650.8253 2.03 98308 10452 2 1650.828339 826.4199 Lamin-B1 OS=Homo sapiens OX=9606 GN=LMNB1 PE=1 SV=2 5.5 2086.4 - 126324 - - - 1.8185 - 2.047 0.515 - 180.2 1 2 1 0.003 13 0 0 0 1.02E+06 5.01E+05 - - - 4.6824 0.8642 221125_WJC_METTL3_EV_vs_WT_F07.10454.10454.2 0.128 30-Apr R.IAEC[160.03]SSQLAEEEEK[136.11]AK[136.11].N sp|P35580|MYH10_HUMAN 1 1836.8746 0.93 98310 10454 2 1836.877838 919.4446 Myosin-10 OS=Homo sapiens OX=9606 GN=MYH10 PE=1 SV=3 4.33 2086.7 - 73424.6 - - - 1.7579 - 1.004 0.246 - 31.5 1 2 1 0.0032 16 0 0 0 5.86E+05 6.28E+05 - - - 0.8668 1 221125_WJC_METTL3_EV_vs_WT_F07.10461.10461.2 3.98E-10 14/24 K.QEYDESGPSIVHR.K "sp|Q6S8J3|POTEE_HUMAN,sp|P63261|ACTG_HUMAN,sp|Q9BYX7|ACTBM_HUMAN,sp|P60709|ACTB_HUMAN,sp|A5A3E0|POTEF_HUMAN,sp|P0CG38|POTEI_HUMAN,sp|P0CG39|POTEJ_HUMAN,tr|A0A2R8YFE2|A0A2R8YFE2_HUMAN,tr|A0A804GS07|A0A804GS07_HUMAN,tr|A0A6Q8PFE4|A0A6Q8PFE4_HUMAN,tr|I3L4N8|I3L4N8_HUMAN" 11 1515.6954 1.03 98315 10461 2 1515.695845 758.855 POTE ankyrin domain family member E OS=Homo sapiens OX=9606 GN=POTEE PE=2 SV=3 4.65 2087.6 - 916770 - - - 0.3028 - 3.004 0.703 - 1004.4 1 2 0 0.0005 13 0 0 0 4.16E+07 4.02E+07 - - - 7.0563 1 221125_WJC_METTL3_EV_vs_WT_F07.10462.10462.2 1.19E-08 14/24 K.QEYDESGPSIVHR[166.11].K "sp|Q6S8J3|POTEE_HUMAN,sp|P63261|ACTG_HUMAN,sp|Q9BYX7|ACTBM_HUMAN,sp|P60709|ACTB_HUMAN,sp|A5A3E0|POTEF_HUMAN,sp|P0CG38|POTEI_HUMAN,sp|P0CG39|POTEJ_HUMAN,tr|A0A2R8YFE2|A0A2R8YFE2_HUMAN,tr|A0A804GS07|A0A804GS07_HUMAN,tr|A0A6Q8PFE4|A0A6Q8PFE4_HUMAN,tr|I3L4N8|I3L4N8_HUMAN" 11 1525.7037 1.03 98316 10462 2 1525.702907 763.8591 POTE ankyrin domain family member E OS=Homo sapiens OX=9606 GN=POTEE PE=2 SV=3 4.65 2087.7 - 1.05E+06 - - - -0.4909 - 2.941 0.608 - 1028.8 1 2 0 -0.0007 13 0 0 0 4.16E+07 4.02E+07 - - - 6.3001 1 221125_WJC_METTL3_EV_vs_WT_F07.10464.10464.3 8.21E-06 18/48 R.KLASASLLDTDKR.Y "sp|Q9NY61|AATF_HUMAN,tr|A0A7P0T868|A0A7P0T868_HUMAN,tr|A0A7P0TAR0|A0A7P0TAR0_HUMAN,tr|A0A7P0TBG4|A0A7P0TBG4_HUMAN,tr|A0A7P0Z4N2|A0A7P0Z4N2_HUMAN,tr|A0A087WTH8|A0A087WTH8_HUMAN,tr|A0A7P0Z434|A0A7P0Z434_HUMAN" 7 1416.7936 1.33 98318 10464 3 1416.796869 473.2718 Protein AATF OS=Homo sapiens OX=9606 GN=AATF PE=1 SV=1 8.59 2087.9 - 728839 - - - 2.277 - 3.404 0.55 - 473.5 1 2 0 0.0032 13 0 0 0 7.08E+06 5.32E+06 - - - 7.9923 0.9993 221125_WJC_METTL3_EV_vs_WT_F07.10468.10468.2 0.00125 22-Sep K.QSSSTNYTNELK[136.11].A "sp|Q9UHB6|LIMA1_HUMAN,tr|F8VRN8|F8VRN8_HUMAN,tr|F8VQE1|F8VQE1_HUMAN" 3 1378.6456 1.22 98322 10468 2 1378.648244 690.3301 LIM domain and actin-binding protein 1 OS=Homo sapiens OX=9606 GN=LIMA1 PE=1 SV=1 6 2088.4 - 175326 - - - 1.9265 - 2.355 0.3 - 425.4 1 2 0 0.0027 12 0 0 0 2.00E+07 1.64E+07 - - - 3.5097 0.9962 221125_WJC_METTL3_EV_vs_WT_F07.10470.10470.2 0.000392 24-Aug K.GHTSFVNSC[160.03]YPAR.R sp|Q96DI7|SNR40_HUMAN 1 1494.6674 2.14 98324 10470 2 1494.675528 748.341 U5 small nuclear ribonucleoprotein 40 kDa protein OS=Homo sapiens OX=9606 GN=SNRNP40 PE=1 SV=1 8.23 2088.7 - 123395 - - - 5.44 - 1.667 0.573 - 175 1 2 0 0.0081 13 0 0 0 3.17E+06 1.48E+06 - - - 4.5822 0.9998 221125_WJC_METTL3_EV_vs_WT_F07.10478.10478.3 0.00114 Nov-52 R.YTSIPTSVEESGK[136.11]K[136.11].E "sp|Q9NVI1|FANCI_HUMAN,tr|F8W7R3|F8W7R3_HUMAN,tr|A0A6Q8PGF4|A0A6Q8PGF4_HUMAN,tr|A0A6Q8PH09|A0A6Q8PH09_HUMAN,tr|H3BP78|H3BP78_HUMAN" 5 1540.7956 0.27 98330 10478 3 1540.79472 514.6058 Fanconi anemia group I protein OS=Homo sapiens OX=9606 GN=FANCI PE=1 SV=4 6.14 2089.6 - 547123 - - - -0.5413 - 1.969 0.377 - 84.3 1 2 0 -0.0008 14 0 0 0 1.65E+06 6.04E+06 - - - 4.5435 1 221125_WJC_METTL3_EV_vs_WT_F07.10480.10480.2 1.92E-06 14/22 K.QSSSTNYTNELK.A "sp|Q9UHB6|LIMA1_HUMAN,tr|F8VRN8|F8VRN8_HUMAN,tr|F8VQE1|F8VQE1_HUMAN" 3 1370.6314 1.22 98332 10480 2 1370.62979 686.323 LIM domain and actin-binding protein 1 OS=Homo sapiens OX=9606 GN=LIMA1 PE=1 SV=1 6 2089.8 - 415838 - - - -1.1659 - 3.009 0.574 - 1226.8 1 2 0 -0.0016 12 0 0 0 2.00E+07 1.64E+07 - - - 6.1786 0.9979 221125_WJC_METTL3_EV_vs_WT_F07.10484.10484.2 0.00115 30-Aug R.TVTQVVPAEGQENGQR.E "sp|Q9UKV3|ACINU_HUMAN,tr|G3V3B0|G3V3B0_HUMAN,tr|S4R3H4|S4R3H4_HUMAN,tr|E7EQT4|E7EQT4_HUMAN,tr|G3V3T3|G3V3T3_HUMAN" 5 1711.8489 1.55 98336 10484 2 1711.852879 856.9317 Apoptotic chromatin condensation inducer in the nucleus OS=Homo sapiens OX=9606 GN=ACIN1 PE=1 SV=2 4.53 2090.3 - 153589 - - - 2.3092 - 1.478 0.359 - 109.6 1 2 0 0.004 16 0 0 0 2.22E+06 1.43E+06 - - - 2.6519 0.9997 221125_WJC_METTL3_EV_vs_WT_F07.10487.10487.3 0.199 Nov-44 R.MQHNLEQQIQAR.N "sp|Q13813|SPTN1_HUMAN,tr|A0A0D9SF54|A0A0D9SF54_HUMAN,tr|A0A0D9SGF6|A0A0D9SGF6_HUMAN" 3 1494.7361 1.39 98337 10487 3 1494.738957 499.2527 "Spectrin alpha chain, non-erythrocytic 1 OS=Homo sapiens OX=9606 GN=SPTAN1 PE=1 SV=3" 6.5 2090.7 - 2.94E+06 - - - 1.8813 - 2.298 0.346 - 296.4 1 2 0 0.0028 12 0 0 0 2.99E+07 2.14E+07 - - - 4.7031 1 221125_WJC_METTL3_EV_vs_WT_F07.10488.10488.3 0.00374 16/40 K.WVPEITHHC[160.03]PK[136.11].T "sp|P60953|CDC42_HUMAN,tr|A0A494C1M1|A0A494C1M1_HUMAN,tr|A0A494BZX6|A0A494BZX6_HUMAN,tr|A0A590UJK8|A0A590UJK8_HUMAN,tr|Q5JYX0|Q5JYX0_HUMAN" 5 1410.6958 0.72 98338 10488 3 1410.697615 471.2392 Cell division control protein 42 homolog OS=Homo sapiens OX=9606 GN=CDC42 PE=1 SV=2 6.91 2090.8 - 1.18E+06 - - - 1.2937 - 2.868 0.424 - 535.1 1 2 0 0.0018 11 0 0 0 1.29E+07 1.79E+07 - - - 6.2598 1 221125_WJC_METTL3_EV_vs_WT_F07.10489.10489.3 6.96E-10 17/40 R.HPGSFDVVHVK[136.11].D "sp|P62701|RS4X_HUMAN,sp|P22090|RS4Y1_HUMAN,tr|C9JEH7|C9JEH7_HUMAN" 3 1228.6444 1.01 98339 10489 3 1228.643918 410.5554 "40S ribosomal protein S4, X isoform OS=Homo sapiens OX=9606 GN=RPS4X PE=1 SV=2" 6.92 2090.9 - 929879 - - - -0.3972 - 2.279 0.573 - 345.1 1 2 0 -0.0005 11 0 0 0 5.89E+08 5.85E+08 - - - 7.2683 0.997 221125_WJC_METTL3_EV_vs_WT_F07.10490.10490.4 0.012 14/84 R.IAPRPASGPIRPIVR.C "sp|P26373|RL13_HUMAN,tr|J3QSB4|J3QSB4_HUMAN" 2 1598.9733 1.2 98340 10490 4 1598.974901 400.7506 60S ribosomal protein L13 OS=Homo sapiens OX=9606 GN=RPL13 PE=1 SV=4 12.3 2091 - 506608 - - - 1.0144 - 1.829 0.249 - 127.1 1 2 0 0.0016 15 0 0 0 5.27E+06 4.41E+06 - - - 1.6089 1 221125_WJC_METTL3_EV_vs_WT_F07.10492.10492.2 1.29E-08 28-Nov R.YGDGGSTFQSTTGHC[160.03].V "sp|P31943|HNRH1_HUMAN,tr|H0YBD7|H0YBD7_HUMAN,tr|H0YB39|H0YB39_HUMAN,tr|H0YBG7|H0YBG7_HUMAN,tr|E9PCY7|E9PCY7_HUMAN,tr|D6RIT2|D6RIT2_HUMAN,tr|G8JLB6|G8JLB6_HUMAN" 7 1573.6103 - 98342 10492 2 1573.610966 787.8124 Heterogeneous nuclear ribonucleoprotein H OS=Homo sapiens OX=9606 GN=HNRNPH1 PE=1 SV=4 5.08 2091.2 - 289692 - - - 0.4004 - 2.469 0.763 - 300.1 1 1 0 0.0006 15 0 0 0 - - - - - 6.8984 0.9993 221125_WJC_METTL3_EV_vs_WT_F07.10493.10493.2 7.68E-05 Jul-32 R.LPPNTNDEVDEDPTGNK[136.11].A sp|Q15393|SF3B3_HUMAN 1 1861.8421 1.53 98343 10493 2 1861.845639 931.9283 Splicing factor 3B subunit 3 OS=Homo sapiens OX=9606 GN=SF3B3 PE=1 SV=4 3.77 2091.4 - 253190 - - - 1.8922 - 1.354 0.502 - 69.1 1 2 0 0.0035 17 0 0 0 4.87E+06 3.18E+06 - - - 3.4928 0.9973 221125_WJC_METTL3_EV_vs_WT_F07.10494.10494.3 0.0595 Sep-64 R.LPPNTNDEVDEDPTGNK[136.11].A sp|Q15393|SF3B3_HUMAN 1 1861.8421 1.63 98344 10494 3 1861.842019 621.6213 Splicing factor 3B subunit 3 OS=Homo sapiens OX=9606 GN=SF3B3 PE=1 SV=4 3.77 2091.5 - 201132 - - - -0.0521 - 1.367 0.297 - 18.1 1 2 0 -0.0001 17 0 0 0 4.05E+06 2.49E+06 - - - 2.641 0.9905 221125_WJC_METTL3_EV_vs_WT_F07.10498.10498.2 0.000179 16-Oct Y.PDGIISK[136.11]PK[136.11].N sp|Q86U44|MTA70_HUMAN 1 969.583 0.001 98346 10498 2 969.582792 485.7988 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 9.01 2092 - 2.60E+06 - - - -0.196 - 2.088 0.437 - 319.7 1 1 0 -0.0002 9 0 0 0 0.00E+00 7.52E+07 - - - 4.3985 1 221125_WJC_METTL3_EV_vs_WT_F07.10499.10499.3 7.34E-08 13/60 R.DGQVINETSQHHDDLE.- sp|P08670|VIME_HUMAN 1 1835.7922 - 98347 10499 3 1835.791954 612.938 Vimentin OS=Homo sapiens OX=9606 GN=VIM PE=1 SV=4 4.28 2092.1 - 686772 - - - -0.1335 - 2.636 0.59 - 159.7 1 2 0 -0.0002 16 0 0 0 - - - - - 7.6048 1 221125_WJC_METTL3_EV_vs_WT_F07.10500.10500.3 6.47E-11 25/68 R.LVHQNSASDDAEASMISK[136.11].L "sp|Q13616|CUL1_HUMAN,tr|A0A0C4DGX4|A0A0C4DGX4_HUMAN,tr|A0A590UJ21|A0A590UJ21_HUMAN,tr|A0A590UJ50|A0A590UJ50_HUMAN,tr|A0A590UJ56|A0A590UJ56_HUMAN,tr|A0A590UJC4|A0A590UJC4_HUMAN,tr|A0A590UK34|A0A590UK34_HUMAN" 7 1909.8931 0.65 98348 10500 3 1909.893972 637.6383 Cullin-1 OS=Homo sapiens OX=9606 GN=CUL1 PE=1 SV=2 4.54 2092.2 - 633673 - - - 0.4534 - 4.379 0.693 - 1045.3 1 2 0 0.0009 18 0 0 0 3.93E+06 6.02E+06 - - - 9.9435 0.9976 221125_WJC_METTL3_EV_vs_WT_F07.10504.10504.3 0.121 Sep-40 K.GK[136.11]PVLELPER[166.11]K[136.11].V "sp|Q14527|HLTF_HUMAN,tr|H7C5K0|H7C5K0_HUMAN,tr|A0A0C4DGA6|A0A0C4DGA6_HUMAN" 3 1290.787 1.42 98352 10504 3 1290.785333 431.2696 Helicase-like transcription factor OS=Homo sapiens OX=9606 GN=HLTF PE=1 SV=2 8.59 2092.7 - 403660 - - - -1.2853 - 1.622 0.259 - 71.9 1 2 0 -0.0017 11 0 0 0 9.12E+06 6.43E+06 - - - 2.8011 0.9986 221125_WJC_METTL3_EV_vs_WT_F07.10505.10505.2 0.000393 24-Dec R.VKEVLTDNNLGQR.L "sp|P39880|CUX1_HUMAN,sp|O14529|CUX2_HUMAN,tr|A0A2R8Y852|A0A2R8Y852_HUMAN,tr|A0A2R8YDI1|A0A2R8YDI1_HUMAN" 4 1484.7947 1.63 98353 10505 2 1484.793817 743.4046 Homeobox protein cut-like 1 OS=Homo sapiens OX=9606 GN=CUX1 PE=1 SV=3 6.04 2092.9 - 278831 - - - -0.5987 - 2.26 0.512 - 405.5 1 2 1 -0.0009 13 0 0 0 3.75E+06 2.30E+06 - - - 4.915 0.9988 221125_WJC_METTL3_EV_vs_WT_F07.10511.10511.3 0.00248 Sep-48 R.LYKEELEQTYHAK.L "sp|P20700|LMNB1_HUMAN,tr|E9PBF6|E9PBF6_HUMAN,tr|A0A0D9SFE5|A0A0D9SFE5_HUMAN" 3 1650.8253 1.25 98358 10511 3 1650.825965 551.2824 Lamin-B1 OS=Homo sapiens OX=9606 GN=LMNB1 PE=1 SV=2 5.5 2093.6 - 365097 - - - 0.3804 - 1.802 0.378 - 68.5 1 2 1 0.0006 13 0 0 0 6.30E+07 5.06E+07 - - - 4.3508 1 221125_WJC_METTL3_EV_vs_WT_F07.10513.10513.3 3.36E-05 15/40 R.HPGSFDVVHVK.D "sp|P62701|RS4X_HUMAN,sp|P22090|RS4Y1_HUMAN,tr|C9JEH7|C9JEH7_HUMAN" 3 1220.6302 1.01 98359 10513 3 1220.629962 407.884 "40S ribosomal protein S4, X isoform OS=Homo sapiens OX=9606 GN=RPS4X PE=1 SV=2" 6.92 2093.8 - 8.84E+06 - - - -0.1999 - 2.571 0.515 - 233.1 1 2 0 -0.0002 11 0 0 0 5.90E+08 5.86E+08 - - - 6.9643 0.9999 221125_WJC_METTL3_EV_vs_WT_F07.10514.10514.3 6.90E-11 14/52 K.VDDSSEDKTEFTVK.N "sp|P49588|SYAC_HUMAN,tr|A0A6Q8PGR9|A0A6Q8PGR9_HUMAN,tr|A0A6Q8PFY2|A0A6Q8PFY2_HUMAN,tr|A0A6Q8PFK3|A0A6Q8PFK3_HUMAN,tr|H3BPK7|H3BPK7_HUMAN,tr|A0A6Q8PHJ2|A0A6Q8PHJ2_HUMAN,tr|A0A6Q8PGB5|A0A6Q8PGB5_HUMAN,tr|A0A6Q8PGN5|A0A6Q8PGN5_HUMAN,tr|A0A6Q8PH44|A0A6Q8PH44_HUMAN" 9 1598.7312 1.06 98360 10514 3 1598.734574 533.9177 "Alanine--tRNA ligase, cytoplasmic OS=Homo sapiens OX=9606 GN=AARS1 PE=1 SV=2" 4.11 2093.9 - 1.52E+06 - - - 2.1342 - 2.676 0.65 - 159.2 1 2 1 0.0034 14 0 0 0 1.54E+07 1.45E+07 - - - 8.4018 1 221125_WJC_METTL3_EV_vs_WT_F07.10515.10515.3 1.82E-06 Dec-40 R.HQEGEIFDTEK.E sp|Q02878|RL6_HUMAN 1 1331.5994 0.91 98361 10515 3 1331.59901 444.8737 60S ribosomal protein L6 OS=Homo sapiens OX=9606 GN=RPL6 PE=1 SV=3 4.4 2094 - 981329 - - - -0.2628 - 2.006 0.508 - 241.9 1 2 0 -0.0003 11 0 0 0 1.83E+07 2.02E+07 - - - 6.1812 0.9999 221125_WJC_METTL3_EV_vs_WT_F07.10516.10516.3 6.70E-09 20/68 R.LVHQNSASDDAEASMISK.L "sp|Q13616|CUL1_HUMAN,tr|A0A0C4DGX4|A0A0C4DGX4_HUMAN,tr|A0A590UJ21|A0A590UJ21_HUMAN,tr|A0A590UJ50|A0A590UJ50_HUMAN,tr|A0A590UJ56|A0A590UJ56_HUMAN,tr|A0A590UJC4|A0A590UJC4_HUMAN,tr|A0A590UK34|A0A590UK34_HUMAN" 7 1901.8789 0.65 98362 10516 3 1901.885886 634.9669 Cullin-1 OS=Homo sapiens OX=9606 GN=CUL1 PE=1 SV=2 4.54 2094.2 - 767617 - - - 3.6701 - 2.796 0.568 - 438.2 1 2 0 0.007 18 0 0 0 3.93E+06 6.02E+06 - - - 7.431 0.9996 221125_WJC_METTL3_EV_vs_WT_F07.10517.10517.3 5.99E-05 Dec-48 K.ASAHSIVEC[160.03]DPVR.K "sp|P52732|KIF11_HUMAN,tr|A0A7I2YQY4|A0A7I2YQY4_HUMAN,tr|A0A7I2V3V3|A0A7I2V3V3_HUMAN" 3 1439.6827 3.47 98363 10517 3 1439.687193 480.9015 Kinesin-like protein KIF11 OS=Homo sapiens OX=9606 GN=KIF11 PE=1 SV=2 5.32 2094.3 - 625890 - - - 3.1118 - 2.198 0.404 - 145 1 2 0 0.0045 13 0 0 0 4.95E+07 1.42E+07 - - - 5.1782 0.9519 221125_WJC_METTL3_EV_vs_WT_F07.10518.10518.2 0.765 14-Jul P.DGIISK[136.11]PK[136.11].N sp|Q86U44|MTA70_HUMAN 1 872.5302 0.26 98364 10518 2 872.531024 437.2724 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 8.59 2094.4 - 415570 - - - 0.9238 - 1.446 0.352 - 145.3 1 1 0 0.0008 8 0 0 0 1.55E+06 6.03E+06 - - - 2.7529 0.9938 221125_WJC_METTL3_EV_vs_WT_F07.10519.10519.2 0.000347 18-Aug R.HSDPESDFYR[166.11].G sp|O94864|ST65G_HUMAN 1 1261.5239 1.36 98365 10519 2 1261.515939 631.7692 STAGA complex 65 subunit gamma OS=Homo sapiens OX=9606 GN=SUPT7L PE=1 SV=1 4.54 2094.5 - 404177 - - - -6.3106 - 1.928 0.523 - 138.5 1 2 0 -0.008 10 0 0 0 2.37E+07 1.75E+07 - - - 4.7338 0.9999 221125_WJC_METTL3_EV_vs_WT_F07.10520.10520.2 4.01E-06 28-Nov R.AGGNQAASQLEEAGR.A sp|Q9HBR0|S38AA_HUMAN 1 1457.6859 2.22 98366 10520 2 1457.686247 729.8502 Putative sodium-coupled neutral amino acid transporter 10 OS=Homo sapiens OX=9606 GN=SLC38A10 PE=1 SV=2 4.53 2094.7 - 399884 - - - 0.2497 - 2.271 0.552 - 338.9 1 2 0 0.0004 15 0 0 0 2.72E+06 1.23E+06 - - - 5.1345 0.9999 221125_WJC_METTL3_EV_vs_WT_F07.10521.10521.3 3.11E-05 Dec-68 R.QVVAVTGDGTNDGPALKK.A "sp|Q01814|AT2B2_HUMAN,sp|P20020|AT2B1_HUMAN,sp|Q16720|AT2B3_HUMAN,sp|P23634|AT2B4_HUMAN,tr|A0A804HKZ0|A0A804HKZ0_HUMAN,tr|E7ERY9|E7ERY9_HUMAN,tr|A0A2R8Y4R4|A0A2R8Y4R4_HUMAN,tr|A0A2U3TZI3|A0A2U3TZI3_HUMAN,tr|A0A2U3U055|A0A2U3U055_HUMAN" 9 1768.9319 1.56 98367 10521 3 1768.932969 590.6513 Plasma membrane calcium-transporting ATPase 2 OS=Homo sapiens OX=9606 GN=ATP2B2 PE=1 SV=2 5.96 2094.8 - 349053 - - - 0.5891 - 2.252 0.417 - 105.1 1 2 0 0.001 18 0 0 0 3.28E+06 2.10E+06 - - - 5.2104 1 221125_WJC_METTL3_EV_vs_WT_F07.10522.10522.2 1.43E-08 16/20 R.HQEGEIFDTEK.E sp|Q02878|RL6_HUMAN 1 1331.5994 1.21 98368 10522 2 1331.599715 666.807 60S ribosomal protein L6 OS=Homo sapiens OX=9606 GN=RPL6 PE=1 SV=3 4.4 2094.9 - 327874 - - - 0.2666 - 3.22 0.532 - 761.5 1 2 0 0.0004 11 0 0 0 1.08E+07 8.91E+06 - - - 6.1337 0.9978 221125_WJC_METTL3_EV_vs_WT_F07.10523.10523.2 0.0216 24-Nov R.VK[136.11]EVLTDNNLGQR[166.11].L "sp|P39880|CUX1_HUMAN,sp|O14529|CUX2_HUMAN,tr|A0A2R8Y852|A0A2R8Y852_HUMAN,tr|A0A2R8YDI1|A0A2R8YDI1_HUMAN" 4 1502.8172 1.63 98369 10523 2 1502.815386 752.4159 Homeobox protein cut-like 1 OS=Homo sapiens OX=9606 GN=CUX1 PE=1 SV=3 6.04 2095.1 - 288515 - - - -1.1911 - 2.381 0.434 - 255.1 1 2 1 -0.0018 13 0 0 0 3.75E+06 2.30E+06 - - - 4.4725 0.9998 221125_WJC_METTL3_EV_vs_WT_F07.10524.10524.2 8.80E-06 28-Nov R.AGGNQAASQLEEAGR[166.11].A sp|Q9HBR0|S38AA_HUMAN 1 1467.6942 2.56 98370 10524 2 1467.695255 734.8544 Putative sodium-coupled neutral amino acid transporter 10 OS=Homo sapiens OX=9606 GN=SLC38A10 PE=1 SV=2 4.53 2095.2 - 202765 - - - 0.7508 - 2.03 0.455 - 275.7 1 2 0 0.0011 15 0 0 0 3.14E+06 1.23E+06 - - - 4.142 0.9993 221125_WJC_METTL3_EV_vs_WT_F07.10527.10527.3 2.86E-08 15/48 R.VK[136.11]EVLTDNNLGQR[166.11].L "sp|P39880|CUX1_HUMAN,sp|O14529|CUX2_HUMAN,tr|A0A2R8Y852|A0A2R8Y852_HUMAN,tr|A0A2R8YDI1|A0A2R8YDI1_HUMAN" 4 1502.8172 1.51 98372 10527 3 1502.822025 501.9463 Homeobox protein cut-like 1 OS=Homo sapiens OX=9606 GN=CUX1 PE=1 SV=3 6.04 2095.6 - 4.18E+06 - - - 3.2266 - 2.726 0.466 - 278.4 1 2 1 0.0048 13 0 0 0 4.99E+07 3.31E+07 - - - 6.4531 0.9993 221125_WJC_METTL3_EV_vs_WT_F07.10528.10528.3 0.00444 14/40 K.WVPEITHHC[160.03]PK.T "sp|P60953|CDC42_HUMAN,tr|A0A494C1M1|A0A494C1M1_HUMAN,tr|A0A494BZX6|A0A494BZX6_HUMAN,tr|A0A590UJK8|A0A590UJK8_HUMAN,tr|Q5JYX0|Q5JYX0_HUMAN" 5 1402.6816 0.69 98373 10528 3 1402.678717 468.5678 Cell division control protein 42 homolog OS=Homo sapiens OX=9606 GN=CDC42 PE=1 SV=2 6.91 2095.6 - 1.91E+06 - - - -2.0482 - 2.315 0.278 - 360.2 1 2 0 -0.0029 11 0 0 0 1.27E+07 1.84E+07 - - - 4.0233 1 221125_WJC_METTL3_EV_vs_WT_F07.10532.10532.2 2.22E-07 18-Nov R.HSDPESDFYR.G sp|O94864|ST65G_HUMAN 1 1251.5156 1.33 98377 10532 2 1251.51479 626.7651 STAGA complex 65 subunit gamma OS=Homo sapiens OX=9606 GN=SUPT7L PE=1 SV=1 4.54 2096 - 1.03E+06 - - - -0.6712 - 2.317 0.662 - 341.8 1 2 0 -0.0008 10 0 0 0 2.32E+07 1.75E+07 - - - 6.2757 1 221125_WJC_METTL3_EV_vs_WT_F07.10536.10536.2 1.88E-06 15/20 R.HQEGEIFDTEK[136.11].E sp|Q02878|RL6_HUMAN 1 1339.6136 1.21 98381 10536 2 1339.61392 670.8141 60S ribosomal protein L6 OS=Homo sapiens OX=9606 GN=RPL6 PE=1 SV=3 4.4 2096.5 - 641842 - - - 0.2687 - 2.853 0.602 - 612 1 2 0 0.0004 11 0 0 0 1.08E+07 8.91E+06 - - - 6.3234 0.9998 221125_WJC_METTL3_EV_vs_WT_F07.10539.10539.3 7.78E-05 Sep-36 R.HSDPESDFYR.G sp|O94864|ST65G_HUMAN 1 1251.5156 1.25 98384 10539 3 1251.51234 418.1792 STAGA complex 65 subunit gamma OS=Homo sapiens OX=9606 GN=SUPT7L PE=1 SV=1 4.54 2096.9 - 414606 - - - -2.6288 - 1.711 0.499 - 178.4 1 2 0 -0.0033 10 0 0 0 7.44E+06 5.95E+06 - - - 5.6709 0.9999 221125_WJC_METTL3_EV_vs_WT_F07.10547.10547.3 0.000528 13/44 R.ESLSTSSDLYKR.S sp|Q8TB72|PUM2_HUMAN 1 1384.6834 1.93 98390 10547 3 1384.684211 462.5684 Pumilio homolog 2 OS=Homo sapiens OX=9606 GN=PUM2 PE=1 SV=2 6.17 2097.8 - 4.06E+06 - - - 0.5684 - 2.861 0.385 - 389.3 1 2 0 0.0008 12 0 0 0 4.19E+07 2.17E+07 - - - 5.7458 0.9997 221125_WJC_METTL3_EV_vs_WT_F07.10548.10548.3 0.000123 13/44 R.ESLSTSSDLYK[136.11]R[166.11].S sp|Q8TB72|PUM2_HUMAN 1 1402.7059 2.15 98391 10548 3 1402.70941 468.5759 Pumilio homolog 2 OS=Homo sapiens OX=9606 GN=PUM2 PE=1 SV=2 6.17 2097.9 - 2.37E+06 - - - 2.5066 - 3.04 0.307 - 399.1 1 2 0 0.0035 12 0 0 0 3.43E+07 1.59E+07 - - - 5.0437 0.9999 221125_WJC_METTL3_EV_vs_WT_F07.10550.10550.3 7.35E-06 14/52 R.MEEKDYTVTQVPPK.H "sp|Q8N5Z5|KCD17_HUMAN,tr|A0A087WX35|A0A087WX35_HUMAN,tr|H0Y731|H0Y731_HUMAN" 3 1663.8127 5.71 98393 10550 3 1663.81344 555.6115 BTB\POZ domain-containing protein KCTD17 OS=Homo sapiens OX=9606 GN=KCTD17 PE=1 SV=3 4.68 2098 - 2.38E+06 - - - 0.4303 - 2.201 0.596 - 195.8 1 2 1 0.0007 14 0 0 0 3.52E+07 6.16E+06 - - - 7.2812 0.9995 221125_WJC_METTL3_EV_vs_WT_F07.10551.10551.3 0.00214 13/32 R.RKVDWLTEK.M "sp|Q14240|IF4A2_HUMAN,sp|P38919|IF4A3_HUMAN,sp|P60842|IF4A1_HUMAN,tr|J3QL52|J3QL52_HUMAN,tr|J3KT12|J3KT12_HUMAN,tr|J3QS69|J3QS69_HUMAN,tr|I3L3H2|I3L3H2_HUMAN,tr|J3QL43|J3QL43_HUMAN,tr|J3KTN0|J3KTN0_HUMAN,tr|E7EQG2|E7EQG2_HUMAN,tr|J3KSZ0|J3KSZ0_HUMAN" 11 1173.6506 1.14 98394 10551 3 1173.650467 392.2241 Eukaryotic initiation factor 4A-II OS=Homo sapiens OX=9606 GN=EIF4A2 PE=1 SV=2 8.59 2098.1 - 1.60E+06 - - - -0.1193 - 2.433 0.353 - 343.3 1 2 1 -0.0001 9 0 0 0 3.04E+07 2.66E+07 - - - 5.1552 0.9987 221125_WJC_METTL3_EV_vs_WT_F07.10553.10553.3 0.207 Nov-32 R.R[166.11]K[136.11]VDWLTEK[136.11].M "sp|Q14240|IF4A2_HUMAN,sp|P38919|IF4A3_HUMAN,sp|P60842|IF4A1_HUMAN,tr|J3QL52|J3QL52_HUMAN,tr|J3KT12|J3KT12_HUMAN,tr|J3QS69|J3QS69_HUMAN,tr|I3L3H2|I3L3H2_HUMAN,tr|J3QL43|J3QL43_HUMAN,tr|J3KTN0|J3KTN0_HUMAN,tr|E7EQG2|E7EQG2_HUMAN,tr|J3KSZ0|J3KSZ0_HUMAN" 11 1199.6873 1.27 98396 10553 3 1199.687754 400.903 Eukaryotic initiation factor 4A-II OS=Homo sapiens OX=9606 GN=EIF4A2 PE=1 SV=2 8.59 2098.2 - 1.46E+06 - - - 0.3976 - 2.223 0.299 - 212.7 1 2 1 0.0005 9 0 0 0 3.37E+07 2.66E+07 - - - 4.281 0.9996 221125_WJC_METTL3_EV_vs_WT_F07.10556.10556.2 0.00226 22-Aug R.ESLSTSSDLYKR.S sp|Q8TB72|PUM2_HUMAN 1 1384.6834 2.56 98399 10556 2 1384.684194 693.349 Pumilio homolog 2 OS=Homo sapiens OX=9606 GN=PUM2 PE=1 SV=2 6.17 2098.6 - 356305 - - - 0.5561 - 1.87 0.382 - 234.6 1 2 0 0.0008 12 0 0 0 2.83E+06 1.10E+06 - - - 3.5092 0.9994 221125_WJC_METTL3_EV_vs_WT_F07.10562.10562.3 0.000569 14/52 K.EAEPIPETVKPEEK.E "sp|O75586|MED6_HUMAN,tr|G3V4A5|G3V4A5_HUMAN,tr|A0A087WYL7|A0A087WYL7_HUMAN" 3 1594.809 1.82 98403 10562 3 1594.8095 532.6103 Mediator of RNA polymerase II transcription subunit 6 OS=Homo sapiens OX=9606 GN=MED6 PE=1 SV=2 4.33 2099.4 - 970813 - - - 0.3022 - 2.159 0.278 - 274 1 2 0 0.0005 14 0 0 0 1.52E+07 8.34E+06 - - - 3.6846 1 221125_WJC_METTL3_EV_vs_WT_F07.10564.10564.3 0.000631 18/56 K.LEHTAQTYSELQGER[166.11].L "sp|O95071|UBR5_HUMAN,tr|E7EMW7|E7EMW7_HUMAN" 2 1770.8412 0.65 98405 10564 3 1770.842799 591.2877 E3 ubiquitin-protein ligase UBR5 OS=Homo sapiens OX=9606 GN=UBR5 PE=1 SV=2 4.75 2099.6 - 706134 - - - 0.8962 - 3.093 0.503 - 371.5 1 2 0 0.0016 15 0 0 0 7.44E+06 1.15E+07 - - - 7.0939 0.9996 221125_WJC_METTL3_EV_vs_WT_F07.10567.10567.2 1.11E-05 24-Nov K.ASAHSIVEC[160.03]DPVR.K "sp|P52732|KIF11_HUMAN,tr|A0A7I2YQY4|A0A7I2YQY4_HUMAN,tr|A0A7I2V3V3|A0A7I2V3V3_HUMAN" 3 1439.6827 9.13 98408 10567 2 1439.685509 720.8486 Kinesin-like protein KIF11 OS=Homo sapiens OX=9606 GN=KIF11 PE=1 SV=2 5.32 2100 - 192902 - - - 1.9421 - 2.082 0.467 - 298.7 1 2 0 0.0028 13 0 0 0 5.11E+06 5.60E+05 - - - 4.3715 0.9996 221125_WJC_METTL3_EV_vs_WT_F07.10568.10568.2 0.0209 26-Jul R.TNFYAEQGGQASDR.G sp|Q5JTZ9|SYAM_HUMAN 1 1542.6699 1.01 98409 10568 2 1542.670185 772.3422 "Alanine--tRNA ligase, mitochondrial OS=Homo sapiens OX=9606 GN=AARS2 PE=1 SV=1" 4.37 2100.1 - 162284 - - - 0.1854 - 1.697 0.388 - 78.6 1 2 0 0.0003 14 0 0 0 9.22E+06 9.16E+06 - - - 3.2338 0.9999 221125_WJC_METTL3_EV_vs_WT_F07.10570.10570.3 0.0037 Dec-44 R.DNPKPNVSEALR.S sp|P82909|RT36_HUMAN 1 1338.6892 1.8 98410 10570 3 1338.689151 447.237 "28S ribosomal protein S36, mitochondrial OS=Homo sapiens OX=9606 GN=MRPS36 PE=1 SV=2" 6.07 2100.4 - 2.20E+06 - - - -0.0202 - 2.238 0.426 - 226.5 1 2 0 0 12 0 0 0 1.01E+08 5.60E+07 - - - 5.5224 0.9998 221125_WJC_METTL3_EV_vs_WT_F07.10571.10571.3 0.00619 Sep-48 K.QEYDESGPSIVHR[166.11].K "sp|Q6S8J3|POTEE_HUMAN,sp|P63261|ACTG_HUMAN,sp|Q9BYX7|ACTBM_HUMAN,sp|P60709|ACTB_HUMAN,sp|A5A3E0|POTEF_HUMAN,sp|P0CG38|POTEI_HUMAN,sp|P0CG39|POTEJ_HUMAN,tr|A0A2R8YFE2|A0A2R8YFE2_HUMAN,tr|A0A804GS07|A0A804GS07_HUMAN,tr|A0A6Q8PFE4|A0A6Q8PFE4_HUMAN,tr|I3L4N8|I3L4N8_HUMAN" 11 1525.7037 1.04 98411 10571 3 1525.706838 509.5752 POTE ankyrin domain family member E OS=Homo sapiens OX=9606 GN=POTEE PE=2 SV=3 4.65 2100.5 - 2.00E+06 - - - 2.0856 - 1.839 0.456 - 121.4 1 2 0 0.0032 13 0 0 0 7.98E+08 7.69E+08 - - - 5.2748 0.9998 221125_WJC_METTL3_EV_vs_WT_F07.10573.10573.3 0.0194 17/56 R.NYLEPGK[136.11]EC[160.03]VQPATK[136.11].S "sp|P16615|AT2A2_HUMAN,tr|H7C5W9|H7C5W9_HUMAN" 2 1748.8738 1.33 98413 10573 3 1748.872316 583.9652 Sarcoplasmic\endoplasmic reticulum calcium ATPase 2 OS=Homo sapiens OX=9606 GN=ATP2A2 PE=1 SV=1 6.13 2100.7 - 567976 - - - -0.8606 - 2.499 0.469 - 373.3 1 2 1 -0.0015 15 0 0 0 5.43E+07 4.07E+07 - - - 6.1584 0.9999 221125_WJC_METTL3_EV_vs_WT_F07.10574.10574.3 3.63E-06 Oct-56 K.LEHTAQTYSELQGER.L "sp|O95071|UBR5_HUMAN,tr|E7EMW7|E7EMW7_HUMAN" 2 1760.8329 0.57 98414 10574 3 1760.832063 587.9516 E3 ubiquitin-protein ligase UBR5 OS=Homo sapiens OX=9606 GN=UBR5 PE=1 SV=2 4.75 2100.8 - 491441 - - - -0.4992 - 1.88 0.502 - 61 1 2 0 -0.0009 15 0 0 0 6.51E+06 1.14E+07 - - - 5.7838 0.9999 221125_WJC_METTL3_EV_vs_WT_F07.10578.10578.2 0.338 13/18 R.YPDGIISK[136.11]PK[136.11].N sp|Q86U44|MTA70_HUMAN 1 1132.6463 0.01 98417 10578 2 1132.646195 567.3304 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 8.5 2101.3 - 1.35E+07 - - - -0.1015 - 2.139 0.536 - 635.8 1 2 0 -0.0001 10 0 0 0 3.00E+06 3.24E+08 - - - 5.1222 0.9993 221125_WJC_METTL3_EV_vs_WT_F07.10582.10582.3 0.000747 Oct-32 R.MDYEDDRLR.D "sp|P43243|MATR3_HUMAN,tr|A8MXP9|A8MXP9_HUMAN,tr|D6R991|D6R991_HUMAN,tr|A0A0R4J2E8|A0A0R4J2E8_HUMAN,tr|D6REM6|D6REM6_HUMAN" 5 1211.5241 1.28 98421 10582 3 1211.525428 404.8486 Matrin-3 OS=Homo sapiens OX=9606 GN=MATR3 PE=1 SV=2 4.23 2101.7 - 838257 - - - 1.1077 - 1.836 0.406 - 271 1 2 1 0.0013 9 0 0 0 1.92E+07 1.50E+07 - - - 4.8973 0.9999 221125_WJC_METTL3_EV_vs_WT_F07.10587.10587.2 3.44E-07 26-Oct R.STSQGSINSPVYSR[166.11].H "sp|O14639|ABLM1_HUMAN,tr|F8W8M4|F8W8M4_HUMAN,tr|A0A494C1G0|A0A494C1G0_HUMAN,tr|J3QSX6|J3QSX6_HUMAN,tr|A0A3B3IS55|A0A3B3IS55_HUMAN,tr|H0Y7N6|H0Y7N6_HUMAN,tr|A0A0A0MRL6|A0A0A0MRL6_HUMAN,tr|A0A494C1P1|A0A494C1P1_HUMAN,tr|F6XFR5|F6XFR5_HUMAN" 9 1491.7193 1.03 98426 10587 2 1491.720171 746.8669 Actin-binding LIM protein 1 OS=Homo sapiens OX=9606 GN=ABLIM1 PE=1 SV=3 8.46 2102.3 - 241659 - - - 0.5799 - 2.22 0.591 - 412.2 1 2 0 0.0009 14 0 0 0 2.83E+06 2.75E+06 - - - 5.4072 0.9999 221125_WJC_METTL3_EV_vs_WT_F07.10589.10589.2 1.80E-05 13/20 R.HPGSFDVVHVK[136.11].D "sp|P62701|RS4X_HUMAN,sp|P22090|RS4Y1_HUMAN,tr|C9JEH7|C9JEH7_HUMAN" 3 1228.6444 1.95 98427 10589 2 1228.645348 615.3295 "40S ribosomal protein S4, X isoform OS=Homo sapiens OX=9606 GN=RPS4X PE=1 SV=2" 6.92 2102.5 - 800505 - - - 0.7667 - 2.292 0.581 - 348.3 1 2 0 0.0009 11 0 0 0 3.21E+07 1.64E+07 - - - 5.5758 1 221125_WJC_METTL3_EV_vs_WT_F07.10591.10591.3 1.87E-05 15/48 K.SLSSSLDDTEVK[136.11]K[136.11].V sp|O95292|VAPB_HUMAN 1 1423.7377 1.21 98428 10591 3 1423.738435 475.5865 Vesicle-associated membrane protein-associated protein B\C OS=Homo sapiens OX=9606 GN=VAPB PE=1 SV=3 4.56 2102.7 - 1.40E+06 - - - 0.5134 - 2.422 0.481 - 181 1 2 0 0.0007 13 0 0 0 1.01E+08 8.36E+07 - - - 6.3009 1 221125_WJC_METTL3_EV_vs_WT_F07.10593.10593.3 9.54E-08 15/48 K.SLSSSLDDTEVKK.V sp|O95292|VAPB_HUMAN 1 1407.7093 1.21 98430 10593 3 1407.709266 470.2437 Vesicle-associated membrane protein-associated protein B\C OS=Homo sapiens OX=9606 GN=VAPB PE=1 SV=3 4.56 2102.9 - 1.37E+06 - - - -0.027 - 2.816 0.582 - 168.9 1 2 0 0 13 0 0 0 1.01E+08 8.36E+07 - - - 7.8358 0.9998 221125_WJC_METTL3_EV_vs_WT_F07.10594.10594.3 1.38E-05 Dec-44 -.MGHQQLYWSHPR.K "sp|P62273|RS29_HUMAN,tr|A0A2R8Y851|A0A2R8Y851_HUMAN" 2 1538.7201 3.42 98431 10594 3 1538.723592 513.914 40S ribosomal protein S29 OS=Homo sapiens OX=9606 GN=RPS29 PE=1 SV=2 8.54 2103 - 1.93E+06 - - - 2.2688 - 1.857 0.447 - 188.2 1 2 0 0.0035 12 0 0 0 1.86E+07 5.45E+06 - - - 5.2383 0.9997 221125_WJC_METTL3_EV_vs_WT_F07.10595.10595.3 0.000712 Oct-48 R.AK[136.11]SDLLGK[136.11]PLGPR[166.11].T "sp|Q8IY67|RAVR1_HUMAN,tr|E9PAU2|E9PAU2_HUMAN,tr|A0A087WZ13|A0A087WZ13_HUMAN" 3 1376.835 0.88 98432 10595 3 1376.834915 459.9523 Ribonucleoprotein PTB-binding 1 OS=Homo sapiens OX=9606 GN=RAVER1 PE=1 SV=1 9.99 2103 - 784399 - - - -0.0646 - 2.265 0.441 - 98.3 1 2 1 -0.0001 13 0 0 0 1.01E+08 1.15E+08 - - - 5.6734 0.9999 221125_WJC_METTL3_EV_vs_WT_F07.10596.10596.2 2.70E-06 26-Nov R.STSQGSINSPVYSR.H "sp|O14639|ABLM1_HUMAN,tr|F8W8M4|F8W8M4_HUMAN,tr|A0A494C1G0|A0A494C1G0_HUMAN,tr|J3QSX6|J3QSX6_HUMAN,tr|A0A3B3IS55|A0A3B3IS55_HUMAN,tr|H0Y7N6|H0Y7N6_HUMAN,tr|A0A0A0MRL6|A0A0A0MRL6_HUMAN,tr|A0A494C1P1|A0A494C1P1_HUMAN,tr|F6XFR5|F6XFR5_HUMAN" 9 1481.711 0.99 98433 10596 2 1481.709536 741.8628 Actin-binding LIM protein 1 OS=Homo sapiens OX=9606 GN=ABLIM1 PE=1 SV=3 8.46 2103.2 - 267635 - - - -1.0123 - 2.372 0.609 - 444 1 2 0 -0.0015 14 0 0 0 2.83E+06 2.86E+06 - - - 5.7061 0.9979 221125_WJC_METTL3_EV_vs_WT_F07.10600.10600.3 0.000188 Oct-32 K.YK[136.11]DDPVDLR[166.11].L "sp|Q9Y2W1|TR150_HUMAN,tr|A0A3B3ITZ9|A0A3B3ITZ9_HUMAN" 2 1137.5785 0.001 98435 10600 3 1137.578741 380.2001 Thyroid hormone receptor-associated protein 3 OS=Homo sapiens OX=9606 GN=THRAP3 PE=1 SV=2 4.43 2103.7 - 2.88E+06 - - - 0.2048 - 1.77 0.326 - 174.7 1 2 1 0.0002 9 0 0 0 0.00E+00 3.33E+07 - - - 3.8953 0.998 221125_WJC_METTL3_EV_vs_WT_F07.10603.10603.3 0.29 21/72 A.AAAAAAGYPGQQQNFHSVR.E sp|Q12948|FOXC1_HUMAN 1 1942.9398 1.31 98438 10603 3 1942.941677 648.6539 Forkhead box protein C1 OS=Homo sapiens OX=9606 GN=FOXC1 PE=1 SV=3 8.8 2104.1 - 443232 - - - 0.9625 - 3.464 0.511 - 504.1 1 1 0 0.0019 19 0 0 0 3.58E+06 2.74E+06 - - - 7.289 0.9805 221125_WJC_METTL3_EV_vs_WT_F07.10604.10604.3 2.06E-05 Oct-60 A.SASC[160.03]AHDPAAAAAALK.S sp|Q96F45|ZN503_HUMAN 1 1510.7198 0.3 98439 10604 3 1510.723479 504.5806 Zinc finger protein 503 OS=Homo sapiens OX=9606 GN=ZNF503 PE=1 SV=1 6.46 2104.1 - 423514 - - - 2.4181 - 1.998 0.464 - 89.5 1 1 0 0.0037 16 0 0 0 9.47E+06 3.17E+07 - - - 5.4881 0.9999 221125_WJC_METTL3_EV_vs_WT_F07.10605.10605.2 0.00011 24-Dec K.SLSSSLDDTEVK[136.11]K[136.11].V sp|O95292|VAPB_HUMAN 1 1423.7377 1.45 98440 10605 2 1423.737149 712.8761 Vesicle-associated membrane protein-associated protein B\C OS=Homo sapiens OX=9606 GN=VAPB PE=1 SV=3 4.56 2104.3 - 316748 - - - -0.3898 - 2.398 0.475 - 330.3 1 2 0 -0.0006 13 0 0 0 1.27E+07 8.72E+06 - - - 4.794 0.9978 221125_WJC_METTL3_EV_vs_WT_F07.10606.10606.2 1.07E-05 26-Aug K.DDPENDNSELPTAK[136.11].E "sp|Q93009|UBP7_HUMAN,tr|A0A669KBL1|A0A669KBL1_HUMAN,tr|H3BND8|H3BND8_HUMAN" 3 1551.678 1.33 98441 10606 2 1551.670186 776.8463 Ubiquitin carboxyl-terminal hydrolase 7 OS=Homo sapiens OX=9606 GN=USP7 PE=1 SV=2 3.77 2104.4 - 199105 - - - -5.0429 - 1.633 0.641 - 133.2 1 2 0 -0.0078 14 0 0 0 1.18E+07 8.86E+06 - - - 5.0037 0.9997 221125_WJC_METTL3_EV_vs_WT_F07.10609.10609.3 0.000106 Dec-44 R.SRAEAESWYQTK.Y "sp|P48668|K2C6C_HUMAN,sp|P04259|K2C6B_HUMAN,sp|O95678|K2C75_HUMAN,sp|P02538|K2C6A_HUMAN" 4 1454.679 762.98 98442 10609 3 1454.679766 485.9003 "Keratin, type II cytoskeletal 6C OS=Homo sapiens OX=9606 GN=KRT6C PE=1 SV=3" 5.86 2104.8 - 2.32E+06 - - - 0.5218 - 2.293 0.443 - 239.5 1 2 1 0.0008 12 0 0 0 4.08E+09 5.34E+06 - - - 5.7791 1 221125_WJC_METTL3_EV_vs_WT_F07.10610.10610.3 6.39E-09 15/56 R.TLHSDDEGTVLDDSR.A "sp|O00170|AIP_HUMAN,tr|A0A804HKP8|A0A804HKP8_HUMAN,tr|E9PMH2|E9PMH2_HUMAN,tr|V9GYQ3|V9GYQ3_HUMAN,tr|A0A804HKH9|A0A804HKH9_HUMAN,tr|A0A804HIX8|A0A804HIX8_HUMAN,tr|A0A804HJ38|A0A804HJ38_HUMAN" 7 1658.7384 1.43 98443 10610 3 1658.739338 553.9201 AH receptor-interacting protein OS=Homo sapiens OX=9606 GN=AIP PE=1 SV=2 4.03 2104.9 - 1.73E+06 - - - 0.5818 - 2.867 0.621 - 280.9 1 2 0 0.001 15 0 0 0 4.38E+07 3.06E+07 - - - 8.2116 0.9983 221125_WJC_METTL3_EV_vs_WT_F07.10611.10611.3 0.00139 Nov-48 K.GSVHSVSFSPDGR.K "sp|Q15269|PWP2_HUMAN,tr|A0A0B4J2E5|A0A0B4J2E5_HUMAN" 2 1330.6266 1.3 98444 10611 3 1330.627621 444.5495 Periodic tryptophan protein 2 homolog OS=Homo sapiens OX=9606 GN=PWP2 PE=2 SV=2 6.74 2105 - 1.33E+06 - - - 0.7838 - 1.837 0.248 - 120.1 1 2 0 0.001 13 0 0 0 2.17E+07 1.67E+07 - - - 2.9535 0.9819 221125_WJC_METTL3_EV_vs_WT_F07.10612.10612.3 0.248 Jul-48 K.GSVHSVSFSPDGR[166.11].K "sp|Q15269|PWP2_HUMAN,tr|A0A0B4J2E5|A0A0B4J2E5_HUMAN" 2 1340.6348 1.33 98445 10612 3 1340.635104 447.8856 Periodic tryptophan protein 2 homolog OS=Homo sapiens OX=9606 GN=PWP2 PE=2 SV=2 6.74 2105 - 1.18E+06 - - - 0.191 - 1.259 0.205 - 66.8 1 2 0 0.0003 13 0 0 0 2.13E+07 1.60E+07 - - - 1.4499 0.9999 221125_WJC_METTL3_EV_vs_WT_F07.10613.10613.3 8.11E-06 13/56 R.TLHSDDEGTVLDDSR[166.11].A "sp|O00170|AIP_HUMAN,tr|A0A804HKP8|A0A804HKP8_HUMAN,tr|E9PMH2|E9PMH2_HUMAN,tr|V9GYQ3|V9GYQ3_HUMAN,tr|A0A804HKH9|A0A804HKH9_HUMAN,tr|A0A804HIX8|A0A804HIX8_HUMAN,tr|A0A804HJ38|A0A804HJ38_HUMAN" 7 1668.7466 1.42 98446 10613 3 1668.749568 557.2562 AH receptor-interacting protein OS=Homo sapiens OX=9606 GN=AIP PE=1 SV=2 4.03 2105.1 - 1.14E+06 - - - 1.7528 - 2.495 0.492 - 228.7 1 2 0 0.0029 15 0 0 0 4.41E+07 3.11E+07 - - - 6.4102 0.9988 221125_WJC_METTL3_EV_vs_WT_F07.10614.10614.3 0.0084 Nov-52 K.EQIVPKPEEEVAQK.K "sp|P18621|RL17_HUMAN,tr|J3QLC8|J3QLC8_HUMAN,tr|J3QQT2|J3QQT2_HUMAN,tr|A0A0A0MRF8|A0A0A0MRF8_HUMAN,tr|J3KRX5|J3KRX5_HUMAN,tr|A0A087WXM6|A0A087WXM6_HUMAN,tr|A0A0A6YYL6|A0A0A6YYL6_HUMAN" 7 1622.8516 1.05 98447 10614 3 1622.852748 541.9578 60S ribosomal protein L17 OS=Homo sapiens OX=9606 GN=RPL17 PE=1 SV=3 4.49 2105.2 - 575913 - - - 0.737 - 1.915 0.264 - 108.6 1 2 0 0.0012 14 0 0 0 9.32E+08 8.88E+08 - - - 3.2097 0.9998 221125_WJC_METTL3_EV_vs_WT_F07.10615.10615.3 4.62E-06 18/68 R.VLEQAEGKVEEPENPAAK.E sp|Q9P2D1|CHD7_HUMAN 1 1936.9742 1.79 98448 10615 3 1936.97965 646.6653 Chromodomain-helicase-DNA-binding protein 7 OS=Homo sapiens OX=9606 GN=CHD7 PE=1 SV=3 4.33 2105.3 - 383109 - - - 2.8209 - 2.913 0.585 - 304.2 1 2 1 0.0055 18 0 0 0 4.99E+07 2.79E+07 - - - 7.723 0.9999 221125_WJC_METTL3_EV_vs_WT_F07.10617.10617.2 1.38E-07 28-Oct K.TTDDTTTDNYIAQGK[136.11].R sp|Q7Z2T5|TRM1L_HUMAN 1 1650.7464 0.38 98450 10617 2 1650.74675 826.3805 TRMT1-like protein OS=Homo sapiens OX=9606 GN=TRMT1L PE=1 SV=2 3.93 2105.6 - 278244 - - - 0.1969 - 2.085 0.645 - 300.2 1 2 0 0.0003 15 0 0 0 2.03E+06 5.35E+06 - - - 5.6113 0.9999 221125_WJC_METTL3_EV_vs_WT_F07.10618.10618.2 0.000567 26-Sep R.DHAVVVGVYRPPPK.V sp|P22087|FBRL_HUMAN 1 1532.8463 7.62 98451 10618 2 1532.847322 767.4304 rRNA 2'-O-methyltransferase fibrillarin OS=Homo sapiens OX=9606 GN=FBL PE=1 SV=2 8.6 2105.7 - 82795.3 - - - 0.6361 - 2.196 0.525 - 315.2 1 2 0 0.001 14 0 0 0 1.30E+07 1.71E+06 - - - 4.8924 1 221125_WJC_METTL3_EV_vs_WT_F07.10620.10620.3 2.69E-10 23/52 R.DHAVVVGVYR[166.11]PPPK[136.11].V sp|P22087|FBRL_HUMAN 1 1550.8688 1.21 98452 10620 3 1550.870319 517.9635 rRNA 2'-O-methyltransferase fibrillarin OS=Homo sapiens OX=9606 GN=FBL PE=1 SV=2 8.6 2105.9 - 9.30E+06 - - - 0.9685 - 3.726 0.676 - 878.4 1 2 0 0.0015 14 0 0 0 4.29E+08 3.55E+08 - - - 9.5719 0.9988 221125_WJC_METTL3_EV_vs_WT_F07.10622.10622.2 7.76E-10 17/22 R.SRAEAESWYQTK.Y "sp|P48668|K2C6C_HUMAN,sp|P04259|K2C6B_HUMAN,sp|O95678|K2C75_HUMAN,sp|P02538|K2C6A_HUMAN" 4 1454.679 3032.7 98453 10622 2 1454.68031 728.3468 "Keratin, type II cytoskeletal 6C OS=Homo sapiens OX=9606 GN=KRT6C PE=1 SV=3" 5.86 2106.1 - 1.18E+06 - - - 0.8957 - 2.785 0.538 - 884.3 1 2 1 0.0013 12 0 0 0 7.39E+08 2.44E+05 - - - 5.7092 1 221125_WJC_METTL3_EV_vs_WT_F07.10623.10623.3 1.00E-08 17/52 K.TGTITTFEHAHNMR[166.11].V sp|P13639|EF2_HUMAN 1 1624.7655 0.53 98454 10623 3 1624.765278 542.5958 Elongation factor 2 OS=Homo sapiens OX=9606 GN=EEF2 PE=1 SV=4 6.61 2106.2 - 956362 - - - -0.1637 - 3.154 0.565 - 406.8 1 2 0 -0.0003 14 0 0 0 1.77E+07 3.35E+07 - - - 7.8917 1 221125_WJC_METTL3_EV_vs_WT_F07.10624.10624.3 4.57E-06 15/48 R.VQYTETEPYHNYR[166.11].E "sp|Q86VM9|ZCH18_HUMAN,tr|E7ERS3|E7ERS3_HUMAN" 2 1708.7721 1.28 98455 10624 3 1708.772193 570.598 Zinc finger CCCH domain-containing protein 18 OS=Homo sapiens OX=9606 GN=ZC3H18 PE=1 SV=2 5.4 2106.3 - 935996 - - - 0.0726 - 2.785 0.548 - 322.6 1 2 0 0.0001 13 0 0 0 2.39E+07 1.86E+07 - - - 7.4267 0.9867 221125_WJC_METTL3_EV_vs_WT_F07.10625.10625.3 0.17 Oct-40 K.TYQDIQNTIK[136.11]K[136.11].A "sp|P24928|RPB1_HUMAN,tr|A0A6Q8PGB0|A0A6Q8PGB0_HUMAN" 2 1366.7427 1.57 98456 10625 3 1366.742417 456.5882 DNA-directed RNA polymerase II subunit RPB1 OS=Homo sapiens OX=9606 GN=POLR2A PE=1 SV=2 8.17 2106.4 - 858662 - - - -0.229 - 1.36 0.199 - 80.8 1 2 0 -0.0003 11 0 0 0 2.35E+07 1.50E+07 - - - 1.6321 0.9998 221125_WJC_METTL3_EV_vs_WT_F07.10626.10626.2 1.19E-07 28-Sep K.TTDDTTTDNYIAQGK.R sp|Q7Z2T5|TRM1L_HUMAN 1 1642.7322 0.38 98457 10626 2 1642.733883 822.3734 TRMT1-like protein OS=Homo sapiens OX=9606 GN=TRMT1L PE=1 SV=2 3.93 2106.5 - 159845 - - - 1.0093 - 2.331 0.502 - 271.3 1 2 0 0.0017 15 0 0 0 2.03E+06 5.35E+06 - - - 4.8289 0.9998 221125_WJC_METTL3_EV_vs_WT_F07.10628.10628.2 9.01E-05 28-Aug R.TLHSDDEGTVLDDSR[166.11].A "sp|O00170|AIP_HUMAN,tr|A0A804HKP8|A0A804HKP8_HUMAN,tr|E9PMH2|E9PMH2_HUMAN,tr|V9GYQ3|V9GYQ3_HUMAN,tr|A0A804HKH9|A0A804HKH9_HUMAN,tr|A0A804HIX8|A0A804HIX8_HUMAN,tr|A0A804HJ38|A0A804HJ38_HUMAN" 7 1668.7466 2.16 98459 10628 2 1668.745334 835.3806 AH receptor-interacting protein OS=Homo sapiens OX=9606 GN=AIP PE=1 SV=2 4.03 2106.7 - 99893.7 - - - -0.7844 - 1.648 0.533 - 174.9 1 2 0 -0.0013 15 0 0 0 2.30E+06 1.07E+06 - - - 4.2055 1 221125_WJC_METTL3_EV_vs_WT_F07.10631.10631.3 8.16E-08 15/52 K.ITESVAETAQTIKK.S sp|Q96A49|SYAP1_HUMAN 1 1517.8301 0.76 98460 10631 3 1517.83174 506.9506 Synapse-associated protein 1 OS=Homo sapiens OX=9606 GN=SYAP1 PE=1 SV=1 6.14 2107.1 - 3.61E+06 - - - 1.0884 - 3.361 0.598 - 380 1 2 0 0.0017 14 0 0 0 3.00E+08 3.96E+08 - - - 8.4282 1 221125_WJC_METTL3_EV_vs_WT_F07.10633.10633.3 1.04E-05 15/36 K.KLDEEALLKK.M sp|O43290|SNUT1_HUMAN 1 1185.6969 2.35 98462 10633 3 1185.697772 396.2396 U4\U6.U5 tri-snRNP-associated protein 1 OS=Homo sapiens OX=9606 GN=SART1 PE=1 SV=1 6.18 2107.4 - 607257 - - - 0.7447 - 2.77 0.541 - 374.6 1 2 0 0.0009 10 0 0 0 3.92E+07 1.67E+07 - - - 7.5468 1 221125_WJC_METTL3_EV_vs_WT_F07.10634.10634.3 1.10E-07 16/72 R.AASAGQEPLHNEELAGAGR.V "sp|Q96HY6|DDRGK_HUMAN,tr|A0A0A0MRX2|A0A0A0MRX2_HUMAN" 2 1876.9028 1.72 98463 10634 3 1876.907241 626.6415 DDRGK domain-containing protein 1 OS=Homo sapiens OX=9606 GN=DDRGK1 PE=1 SV=2 4.75 2107.5 - 533003 - - - 2.3912 - 2.822 0.555 - 129.8 1 2 0 0.0045 19 0 0 0 8.97E+06 5.23E+06 - - - 7.2753 0.9999 221125_WJC_METTL3_EV_vs_WT_F07.10635.10635.3 5.14E-06 15/52 K.TGTITTFEHAHNMR.V sp|P13639|EF2_HUMAN 1 1614.7573 0.47 98464 10635 3 1614.762245 539.2597 Elongation factor 2 OS=Homo sapiens OX=9606 GN=EEF2 PE=1 SV=4 6.61 2107.7 - 448141 - - - 3.0785 - 2.384 0.571 - 157.7 1 2 0 0.005 14 0 0 0 1.57E+07 3.30E+07 - - - 7.2135 0.9998 221125_WJC_METTL3_EV_vs_WT_F07.10636.10636.2 0.000106 26-Sep K.ITESVAETAQTIKK.S sp|Q96A49|SYAP1_HUMAN 1 1517.8301 1.25 98465 10636 2 1517.827811 759.9223 Synapse-associated protein 1 OS=Homo sapiens OX=9606 GN=SYAP1 PE=1 SV=1 6.14 2107.8 - 198196 - - - -1.5002 - 2.121 0.498 - 203.3 1 2 0 -0.0023 14 0 0 0 2.12E+07 1.70E+07 - - - 4.6053 0.9999 221125_WJC_METTL3_EV_vs_WT_F07.10637.10637.2 4.15E-05 28-Oct K.NLQEGNEVDSQSSIR.T "sp|O75152|ZC11A_HUMAN,tr|E9PQ61|E9PQ61_HUMAN" 2 1674.7809 1.73 98466 10637 2 1674.782541 838.3977 Zinc finger CCCH domain-containing protein 11A OS=Homo sapiens OX=9606 GN=ZC3H11A PE=1 SV=3 4.14 2107.9 - 88892.9 - - - 0.9762 - 2.495 0.582 - 290.3 1 2 0 0.0016 15 0 0 0 2.39E+06 1.38E+06 - - - 5.587 0.9994 221125_WJC_METTL3_EV_vs_WT_F07.10640.10640.3 0.00114 13/48 R.AKSDLLGKPLGPR.T "sp|Q8IY67|RAVR1_HUMAN,tr|E9PAU2|E9PAU2_HUMAN,tr|A0A087WZ13|A0A087WZ13_HUMAN" 3 1350.7983 0.88 98467 10640 3 1350.797724 451.2734 Ribonucleoprotein PTB-binding 1 OS=Homo sapiens OX=9606 GN=RAVER1 PE=1 SV=1 9.99 2108.3 - 2.54E+06 - - - -0.4516 - 2.195 0.381 - 142 1 2 1 -0.0006 13 0 0 0 1.01E+08 1.15E+08 - - - 4.9192 1 221125_WJC_METTL3_EV_vs_WT_F07.10641.10641.3 9.71E-07 15/48 R.VQYTETEPYHNYR.E "sp|Q86VM9|ZCH18_HUMAN,tr|E7ERS3|E7ERS3_HUMAN" 2 1698.7638 1.28 98468 10641 3 1698.763795 567.2619 Zinc finger CCCH domain-containing protein 18 OS=Homo sapiens OX=9606 GN=ZC3H18 PE=1 SV=2 5.4 2108.4 - 1.59E+06 - - - -0.0024 - 3.111 0.574 - 291.3 1 2 0 0 13 0 0 0 2.39E+07 1.86E+07 - - - 8.0167 0.9999 221125_WJC_METTL3_EV_vs_WT_F07.10642.10642.3 0.000586 13/36 K.K[136.11]LDEEALLK[136.11]K[136.11].M sp|O43290|SNUT1_HUMAN 1 1209.7395 2.35 98469 10642 3 1209.739554 404.2538 U4\U6.U5 tri-snRNP-associated protein 1 OS=Homo sapiens OX=9606 GN=SART1 PE=1 SV=1 6.18 2108.5 - 680354 - - - 0.0537 - 2.246 0.378 - 286.5 1 2 0 0.0001 10 0 0 0 3.92E+07 1.67E+07 - - - 5.1174 0.9998 221125_WJC_METTL3_EV_vs_WT_F07.10645.10645.3 6.82E-05 16/52 R.VK[136.11]GGGHVAQIYAIR[166.11].Q "sp|P62249|RS16_HUMAN,tr|M0R210|M0R210_HUMAN,tr|M0R3H0|M0R3H0_HUMAN,tr|M0QX76|M0QX76_HUMAN,tr|M0R1M5|M0R1M5_HUMAN" 5 1485.8535 0.72 98472 10645 3 1485.852793 496.2918 40S ribosomal protein S16 OS=Homo sapiens OX=9606 GN=RPS16 PE=1 SV=2 9.99 2108.9 - 465085 - - - -0.4772 - 2.435 0.468 - 234.7 1 2 1 -0.0007 14 0 0 0 6.24E+07 8.70E+07 - - - 6.1226 1 221125_WJC_METTL3_EV_vs_WT_F07.10648.10648.2 4.71E-09 13/32 V.FAGTNTGPNNSNTTFQK.R "sp|Q9NYF8|BCLF1_HUMAN,tr|H0YF14|H0YF14_HUMAN" 2 1797.8282 2.38 98475 10648 2 1797.827413 899.9214 Bcl-2-associated transcription factor 1 OS=Homo sapiens OX=9606 GN=BCLAF1 PE=1 SV=2 8.75 2109.3 - 179746 - - - -0.4327 - 2.98 0.649 - 599 1 1 0 -0.0008 17 0 0 0 4.49E+07 1.89E+07 - - - 6.5188 0.9999 221125_WJC_METTL3_EV_vs_WT_F07.10650.10650.2 9.28E-06 28-Sep K.NLQEGNEVDSQSSIR[166.11].T "sp|O75152|ZC11A_HUMAN,tr|E9PQ61|E9PQ61_HUMAN" 2 1684.7892 1.73 98477 10650 2 1684.789488 843.4019 Zinc finger CCCH domain-containing protein 11A OS=Homo sapiens OX=9606 GN=ZC3H11A PE=1 SV=3 4.14 2109.5 - 136475 - - - 0.1852 - 2.14 0.617 - 259.4 1 2 0 0.0003 15 0 0 0 2.39E+06 1.38E+06 - - - 5.4685 0.9998 221125_WJC_METTL3_EV_vs_WT_F07.10654.10654.3 8.60E-10 15/52 K.ITESVAETAQTIK[136.11]K[136.11].S sp|Q96A49|SYAP1_HUMAN 1 1533.8585 0.64 98479 10654 3 1533.855056 512.2934 Synapse-associated protein 1 OS=Homo sapiens OX=9606 GN=SYAP1 PE=1 SV=1 6.14 2109.9 - 2.00E+07 - - - -2.2375 - 3.088 0.335 - 417.9 1 2 0 -0.0034 14 0 0 0 3.00E+08 4.70E+08 - - - 5.2704 1 221125_WJC_METTL3_EV_vs_WT_F07.10655.10655.3 4.86E-06 14/52 K.EQIVPK[136.11]PEEEVAQK[136.11].K "sp|P18621|RL17_HUMAN,tr|J3QLC8|J3QLC8_HUMAN,tr|J3QQT2|J3QQT2_HUMAN,tr|A0A0A0MRF8|A0A0A0MRF8_HUMAN,tr|J3KRX5|J3KRX5_HUMAN,tr|A0A087WXM6|A0A087WXM6_HUMAN,tr|A0A0A6YYL6|A0A0A6YYL6_HUMAN" 7 1638.88 1.05 98480 10655 3 1638.87758 547.3006 60S ribosomal protein L17 OS=Homo sapiens OX=9606 GN=RPL17 PE=1 SV=3 4.49 2110 - 3.81E+06 - - - -1.4473 - 2.54 0.501 - 183.8 1 2 0 -0.0024 14 0 0 0 9.31E+08 8.88E+08 - - - 6.6023 0.9999 221125_WJC_METTL3_EV_vs_WT_F07.10657.10657.3 0.000698 19/52 R.VKGGGHVAQIYAIR.Q "sp|P62249|RS16_HUMAN,tr|M0R210|M0R210_HUMAN,tr|M0R3H0|M0R3H0_HUMAN,tr|M0QX76|M0QX76_HUMAN,tr|M0R1M5|M0R1M5_HUMAN" 5 1467.831 0.72 98482 10657 3 1467.82993 490.2843 40S ribosomal protein S16 OS=Homo sapiens OX=9606 GN=RPS16 PE=1 SV=2 9.99 2110.2 - 1.15E+06 - - - -0.7508 - 3.334 0.461 - 321.5 1 2 1 -0.0011 14 0 0 0 6.24E+07 8.70E+07 - - - 6.8795 0.9983 221125_WJC_METTL3_EV_vs_WT_F07.10658.10658.3 0.00775 Dec-44 K.K[136.11]ANAEELANNLK[136.11].Q "sp|Q86XP3|DDX42_HUMAN,tr|A0A0A0MSJ0|A0A0A0MSJ0_HUMAN" 2 1329.7223 1.51 98483 10658 3 1329.72496 444.2481 ATP-dependent RNA helicase DDX42 OS=Homo sapiens OX=9606 GN=DDX42 PE=1 SV=1 6.14 2110.3 - 620129 - - - 1.9786 - 1.817 0.288 - 107.4 1 2 0 0.0026 12 0 0 0 1.19E+07 7.91E+06 - - - 3.4055 1 221125_WJC_METTL3_EV_vs_WT_F07.10660.10660.2 8.62E-07 19/22 K.KANAEELANNLK.Q "sp|Q86XP3|DDX42_HUMAN,tr|A0A0A0MSJ0|A0A0A0MSJ0_HUMAN" 2 1313.6939 2.44 98485 10660 2 1313.693884 657.8542 ATP-dependent RNA helicase DDX42 OS=Homo sapiens OX=9606 GN=DDX42 PE=1 SV=1 6.14 2110.5 - 414759 - - - -0.0343 - 3.99 0.65 - 1232.4 1 2 0 0 12 0 0 0 4.85E+06 1.99E+06 - - - 7.4829 1 221125_WJC_METTL3_EV_vs_WT_F07.10667.10667.2 2.42E-12 16/32 V.FAGTNTGPNNSNTTFQK[136.11].R "sp|Q9NYF8|BCLF1_HUMAN,tr|H0YF14|H0YF14_HUMAN" 2 1805.8424 2.38 98490 10667 2 1805.842621 903.9285 Bcl-2-associated transcription factor 1 OS=Homo sapiens OX=9606 GN=BCLAF1 PE=1 SV=2 8.75 2111.4 - 545389 - - - 0.1274 - 3.732 0.717 - 892.8 1 1 0 0.0002 17 0 0 0 4.49E+07 1.89E+07 - - - 7.5745 0.9934 221125_WJC_METTL3_EV_vs_WT_F07.10668.10668.4 0.00283 10/108 R.SLYASSPGGVYATRSSAVR.L "sp|P08670|VIME_HUMAN,tr|B0YJC4|B0YJC4_HUMAN,tr|A0A1B0GVG8|A0A1B0GVG8_HUMAN,tr|A0A1B0GTT5|A0A1B0GTT5_HUMAN" 4 1927.9752 1.83 98491 10668 4 1927.981023 483.0011 Vimentin OS=Homo sapiens OX=9606 GN=VIM PE=1 SV=4 9.98 2111.6 - 461523 - - - 3.026 - 1.941 0.332 - 51 1 2 1 0.0058 19 0 0 0 2.71E+06 1.48E+06 - - - 2.3385 0.9997 221125_WJC_METTL3_EV_vs_WT_F07.10669.10669.2 5.30E-06 22-Nov K.K[136.11]ANAEELANNLK[136.11].Q "sp|Q86XP3|DDX42_HUMAN,tr|A0A0A0MSJ0|A0A0A0MSJ0_HUMAN" 2 1329.7223 2.44 98492 10669 2 1329.71928 665.8684 ATP-dependent RNA helicase DDX42 OS=Homo sapiens OX=9606 GN=DDX42 PE=1 SV=1 6.14 2111.7 - 256505 - - - -2.293 - 2.589 0.453 - 293.1 1 2 0 -0.003 12 0 0 0 4.85E+06 1.99E+06 - - - 4.8889 0.7933 221125_WJC_METTL3_EV_vs_WT_F07.10671.10671.3 2.89 Jul-32 R.HMYHSLYLK[136.11].V "sp|P84098|RL19_HUMAN,tr|J3KTE4|J3KTE4_HUMAN,tr|A0A7I2YQG2|A0A7I2YQG2_HUMAN,tr|J3QR09|J3QR09_HUMAN" 4 1198.6048 0.83 98494 10671 3 1198.605785 400.5422 60S ribosomal protein L19 OS=Homo sapiens OX=9606 GN=RPL19 PE=1 SV=1 8.51 2111.9 - 201930 - - - 0.7801 - 1.135 0.096 - 64 1 2 0 0.0009 9 0 0 0 2.89E+06 3.47E+06 - - - -0.0083 0.9998 221125_WJC_METTL3_EV_vs_WT_F07.10675.10675.3 3.80E-07 15/52 K.GQPDVVVK[136.11]EDEEYK[136.11].R "sp|P24752|THIL_HUMAN,tr|A0A5F9ZHJ7|A0A5F9ZHJ7_HUMAN,tr|A0A5F9ZHD4|A0A5F9ZHD4_HUMAN,tr|A0A5F9ZHJ0|A0A5F9ZHJ0_HUMAN,tr|A0A5F9ZHL1|A0A5F9ZHL1_HUMAN,tr|A0A5F9ZI66|A0A5F9ZI66_HUMAN" 6 1649.8119 1.16 98496 10675 3 1649.80955 550.9446 "Acetyl-CoA acetyltransferase, mitochondrial OS=Homo sapiens OX=9606 GN=ACAT1 PE=1 SV=1" 4.18 2112.4 - 1.11E+06 - - - -1.4438 - 2.353 0.516 - 259.1 1 2 1 -0.0024 14 0 0 0 7.69E+07 6.64E+07 - - - 6.5663 1 221125_WJC_METTL3_EV_vs_WT_F07.10678.10678.3 3.90E-08 16/52 K.AIHTLQDVSTC[160.03]ETK.E "sp|Q5VWN6|TASO2_HUMAN,tr|A0A2R8YH03|A0A2R8YH03_HUMAN" 2 1601.7719 1.5 98499 10678 3 1601.770205 534.9313 Protein TASOR 2 OS=Homo sapiens OX=9606 GN=TASOR2 PE=1 SV=1 5.32 2112.7 - 1.35E+06 - - - -1.0719 - 2.733 0.542 - 323.6 1 2 0 -0.0017 14 0 0 0 2.19E+07 1.46E+07 - - - 7.2542 0.9997 221125_WJC_METTL3_EV_vs_WT_F07.10679.10679.3 0.00269 Dec-44 K.KANAEELANNLK.Q "sp|Q86XP3|DDX42_HUMAN,tr|A0A0A0MSJ0|A0A0A0MSJ0_HUMAN" 2 1313.6939 1.51 98500 10679 3 1313.697365 438.9053 ATP-dependent RNA helicase DDX42 OS=Homo sapiens OX=9606 GN=DDX42 PE=1 SV=1 6.14 2112.9 - 956080 - - - 2.6155 - 2.372 0.385 - 229.4 1 2 0 0.0034 12 0 0 0 1.25E+07 8.25E+06 - - - 5.2256 0.9997 221125_WJC_METTL3_EV_vs_WT_F07.10681.10681.2 0.000106 26-Dec K.EQIVPK[136.11]PEEEVAQK[136.11].K "sp|P18621|RL17_HUMAN,tr|J3QLC8|J3QLC8_HUMAN,tr|J3QQT2|J3QQT2_HUMAN,tr|A0A0A0MRF8|A0A0A0MRF8_HUMAN,tr|J3KRX5|J3KRX5_HUMAN,tr|A0A087WXM6|A0A087WXM6_HUMAN,tr|A0A0A6YYL6|A0A0A6YYL6_HUMAN" 7 1638.88 1.05 98502 10681 2 1638.876558 820.4473 60S ribosomal protein L17 OS=Homo sapiens OX=9606 GN=RPL17 PE=1 SV=3 4.49 2113.1 - 607603 - - - -2.0709 - 2.362 0.501 - 395 1 2 0 -0.0034 14 0 0 0 7.55E+07 7.20E+07 - - - 4.8972 1 221125_WJC_METTL3_EV_vs_WT_F07.10685.10685.3 5.43E-06 Nov-44 R.TNHIYVSSDDIK.E sp|Q6P2Q9|PRP8_HUMAN 1 1390.6729 1.42 98504 10685 3 1390.670805 464.5649 Pre-mRNA-processing-splicing factor 8 OS=Homo sapiens OX=9606 GN=PRPF8 PE=1 SV=2 5.18 2113.6 - 2.42E+06 - - - -1.477 - 2.189 0.516 - 228.8 1 2 0 -0.0021 12 0 0 0 1.03E+08 7.31E+07 - - - 6.4639 1 221125_WJC_METTL3_EV_vs_WT_F07.10686.10686.3 3.98E-06 Dec-48 K.DHLQGLDPGEPNK.S sp|Q9UKJ3|GPTC8_HUMAN 1 1418.679 1.22 98505 10686 3 1418.679657 473.9003 G patch domain-containing protein 8 OS=Homo sapiens OX=9606 GN=GPATCH8 PE=1 SV=2 4.54 2113.6 - 1.15E+06 - - - 0.4582 - 2.451 0.517 - 237.2 1 2 0 0.0006 13 0 0 0 2.30E+07 1.88E+07 - - - 6.7345 1 221125_WJC_METTL3_EV_vs_WT_F07.10687.10687.3 2.93E-11 18/64 R.AMIGHTDSAEAAPGTIR.G "sp|O00746|NDKM_HUMAN,tr|Q4TT34|Q4TT34_HUMAN,tr|A0A087WVT9|A0A087WVT9_HUMAN,tr|H0Y6J0|H0Y6J0_HUMAN,tr|F2Z2X0|F2Z2X0_HUMAN" 5 1696.8203 2.53 98506 10687 3 1696.819409 566.614 "Nucleoside diphosphate kinase, mitochondrial OS=Homo sapiens OX=9606 GN=NME4 PE=1 SV=1" 5.32 2113.7 - 871083 - - - -0.5068 - 3.353 0.627 - 286 1 2 0 -0.0009 17 0 0 0 8.13E+07 3.21E+07 - - - 8.5867 0.8503 221125_WJC_METTL3_EV_vs_WT_F07.10689.10689.3 0.688 Sep-36 K.K[136.11]YAELLEEHR[166.11].N sp|P40222|TXLNA_HUMAN 1 1304.6844 1.04 98508 10689 3 1304.680501 435.9021 Alpha-taxilin OS=Homo sapiens OX=9606 GN=TXLNA PE=1 SV=3 5.5 2114 - 571461 - - - -2.9655 - 1.535 0.1 - 138.2 1 2 0 -0.0039 10 0 0 0 6.97E+06 6.70E+06 - - - 0.9053 0.9997 221125_WJC_METTL3_EV_vs_WT_F07.10693.10693.3 5.75E-06 14/48 R.EDLQLDK[136.11]PASGVK[136.11].E "sp|P78347|GTF2I_HUMAN,tr|A0A494C0Q7|A0A494C0Q7_HUMAN,tr|A0A494C1K3|A0A494C1K3_HUMAN" 3 1414.7639 1.36 98510 10693 3 1414.764225 472.5952 General transcription factor II-I OS=Homo sapiens OX=9606 GN=GTF2I PE=1 SV=2 4.56 2114.5 - 908565 - - - 0.2587 - 2.727 0.278 - 252.5 1 2 0 0.0004 13 0 0 0 6.65E+07 4.89E+07 - - - 4.3593 0.9999 221125_WJC_METTL3_EV_vs_WT_F07.10694.10694.3 7.67E-06 14/52 K.NLLIQNK[136.11]PGDDPNK[136.11].L "sp|P35658|NU214_HUMAN,tr|A0A494BZU9|A0A494BZU9_HUMAN,tr|A0A494C1F2|A0A494C1F2_HUMAN" 3 1580.8493 2.37 98511 10694 3 1580.847442 527.957 Nuclear pore complex protein Nup214 OS=Homo sapiens OX=9606 GN=NUP214 PE=1 SV=2 5.96 2114.6 - 1.04E+06 - - - -1.188 - 2.442 0.453 - 219 1 2 0 -0.0019 14 0 0 0 8.24E+07 3.48E+07 - - - 5.9627 0.9989 221125_WJC_METTL3_EV_vs_WT_F07.10695.10695.3 0.000377 Nov-40 K.TVYTGIDHHWK[136.11].E "sp|Q9NV06|DCA13_HUMAN,tr|E5RHM4|E5RHM4_HUMAN,tr|A0A087WT20|A0A087WT20_HUMAN,tr|B3KME9|B3KME9_HUMAN,tr|A0A087X1F8|A0A087X1F8_HUMAN" 5 1363.6764 1.21 98512 10695 3 1363.668832 455.5661 DDB1- and CUL4-associated factor 13 OS=Homo sapiens OX=9606 GN=DCAF13 PE=1 SV=2 6.61 2114.7 - 625425 - - - -5.5754 - 2.295 0.46 - 126.5 1 2 0 -0.0076 11 0 0 0 1.94E+07 1.60E+07 - - - 6.0264 1 221125_WJC_METTL3_EV_vs_WT_F07.10698.10698.2 3.98E-07 Nov-32 R.LPPNTNDEVDEDPTGNK.A sp|Q15393|SF3B3_HUMAN 1 1853.8279 1.51 98514 10698 2 1853.82918 927.9212 Splicing factor 3B subunit 3 OS=Homo sapiens OX=9606 GN=SF3B3 PE=1 SV=4 3.77 2115.1 - 726087 - - - 0.6818 - 2.286 0.697 - 222.3 1 2 0 0.0013 17 0 0 0 3.07E+07 2.03E+07 - - - 6.2214 1 221125_WJC_METTL3_EV_vs_WT_F07.10701.10701.3 1.02E-05 Dec-44 K.SGSSFVHQASFK[136.11].F sp|P49792|RBP2_HUMAN 1 1288.6291 0.81 98516 10701 3 1288.627063 430.5503 E3 SUMO-protein ligase RanBP2 OS=Homo sapiens OX=9606 GN=RANBP2 PE=1 SV=2 8.49 2115.4 - 1.09E+06 - - - -1.6196 - 2.463 0.512 - 202.9 1 2 0 -0.0021 12 0 0 0 1.36E+07 1.68E+07 - - - 6.7462 1 221125_WJC_METTL3_EV_vs_WT_F07.10705.10705.2 3.61E-08 14/22 R.TNHIYVSSDDIK[136.11].E sp|Q6P2Q9|PRP8_HUMAN 1 1398.6871 2.9 98520 10705 2 1398.682786 700.3508 Pre-mRNA-processing-splicing factor 8 OS=Homo sapiens OX=9606 GN=PRPF8 PE=1 SV=2 5.18 2115.9 - 370747 - - - -3.055 - 2.543 0.611 - 679.6 1 2 0 -0.0043 12 0 0 0 1.26E+07 4.35E+06 - - - 6.0083 0.9869 221125_WJC_METTL3_EV_vs_WT_F07.10706.10706.3 0.000701 14/40 R.DTLLALHQHGH.S sp|Q7Z5L9|I2BP2_HUMAN 1 1240.6313 - 98521 10706 3 1240.629127 414.551 Interferon regulatory factor 2-binding protein 2 OS=Homo sapiens OX=9606 GN=IRF2BP2 PE=1 SV=2 6.25 2116 - 338101 - - - -1.7265 - 2.571 0.371 - 259.2 1 1 0 -0.0021 11 0 0 0 - - - - - 5.3583 0.9998 221125_WJC_METTL3_EV_vs_WT_F07.10709.10709.3 0.000534 Oct-44 R.TNHIYVSSDDIK[136.11].E sp|Q6P2Q9|PRP8_HUMAN 1 1398.6871 1.46 98523 10709 3 1398.68566 467.2363 Pre-mRNA-processing-splicing factor 8 OS=Homo sapiens OX=9606 GN=PRPF8 PE=1 SV=2 5.18 2116.3 - 4.44E+06 - - - -1.0002 - 1.823 0.388 - 177.5 1 2 0 -0.0014 12 0 0 0 1.03E+08 7.06E+07 - - - 4.5299 0.9999 221125_WJC_METTL3_EV_vs_WT_F07.10711.10711.3 6.21E-05 Nov-52 K.NLLIQNKPGDDPNK.L "sp|P35658|NU214_HUMAN,tr|A0A494BZU9|A0A494BZU9_HUMAN,tr|A0A494C1F2|A0A494C1F2_HUMAN" 3 1564.8209 2.37 98525 10711 3 1564.821288 522.6142 Nuclear pore complex protein Nup214 OS=Homo sapiens OX=9606 GN=NUP214 PE=1 SV=2 5.96 2116.4 - 4.20E+06 - - - 0.2352 - 1.94 0.417 - 124.7 1 2 0 0.0004 14 0 0 0 8.24E+07 3.48E+07 - - - 4.9501 0.9999 221125_WJC_METTL3_EV_vs_WT_F07.10712.10712.4 8.46E-06 15/78 R.DHAVVVGVYRPPPK.V sp|P22087|FBRL_HUMAN 1 1532.8463 0.92 98526 10712 4 1532.844167 384.2189 rRNA 2'-O-methyltransferase fibrillarin OS=Homo sapiens OX=9606 GN=FBL PE=1 SV=2 8.6 2116.6 - 848594 - - - -1.4222 - 2.524 0.426 - 233.6 1 2 0 -0.0022 14 0 0 0 1.01E+08 1.10E+08 - - - 3.2703 0.9997 221125_WJC_METTL3_EV_vs_WT_F07.10713.10713.4 0.0245 17/78 R.DHAVVVGVYR[166.11]PPPK[136.11].V sp|P22087|FBRL_HUMAN 1 1550.8688 0.92 98527 10713 4 1550.869652 388.7245 rRNA 2'-O-methyltransferase fibrillarin OS=Homo sapiens OX=9606 GN=FBL PE=1 SV=2 8.6 2116.7 - 737553 - - - 0.5384 - 3.013 0.337 - 351 1 2 0 0.0008 14 0 0 0 1.01E+08 1.10E+08 - - - 2.5604 0.9839 221125_WJC_METTL3_EV_vs_WT_F07.10715.10715.2 0.00089 22-Dec L.RQTVEADVNGLR.R sp|P08779|K1C16_HUMAN 1 1356.711 48.31 98529 10715 2 1356.711477 679.3628 "Keratin, type I cytoskeletal 16 OS=Homo sapiens OX=9606 GN=KRT16 PE=1 SV=4" 6.07 2117 - 469159 - - - 0.3693 - 2.671 0.288 - 181.7 1 1 0 0.0005 12 0 0 0 1.38E+08 2.86E+06 - - - 3.753 0.9983 221125_WJC_METTL3_EV_vs_WT_F07.10716.10716.2 0.00248 24-Jul R.IQFK[136.11]PDDGTTPER[166.11].L "sp|Q96AE4|FUBP1_HUMAN,tr|E9PEB5|E9PEB5_HUMAN" 2 1520.759 1.49 98530 10716 2 1520.763673 761.3868 Far upstream element-binding protein 1 OS=Homo sapiens OX=9606 GN=FUBP1 PE=1 SV=3 4.56 2117.1 - 379684 - - - 3.0781 - 1.718 0.4 - 129.4 1 2 0 0.0047 13 0 0 0 8.66E+06 5.81E+06 - - - 3.3828 0.9985 221125_WJC_METTL3_EV_vs_WT_F07.10719.10719.3 0.000131 17/44 L.RQTVEADVNGLR.R sp|P08779|K1C16_HUMAN 1 1356.711 13.06 98531 10719 3 1356.709787 453.2443 "Keratin, type I cytoskeletal 16 OS=Homo sapiens OX=9606 GN=KRT16 PE=1 SV=4" 6.07 2117.5 - 4.40E+06 - - - -0.8764 - 3.268 0.517 - 658.3 1 1 0 -0.0012 12 0 0 0 6.26E+08 4.79E+07 - - - 7.5861 1 221125_WJC_METTL3_EV_vs_WT_F07.10722.10722.2 2.69E-06 20-Oct R.SQYEQLAEQNR.K "sp|P13645|K1C10_HUMAN,tr|A0A1B0GVI3|A0A1B0GVI3_HUMAN" 2 1364.6321 999 98534 10722 2 1364.630612 683.3233 "Keratin, type I cytoskeletal 10 OS=Homo sapiens OX=9606 GN=KRT10 PE=1 SV=6" 4.53 2117.7 - 1.30E+06 - - - -1.0589 - 2.363 0.59 - 365.5 1 2 0 -0.0014 11 0 0 0 3.58E+08 0.00E+00 - - - 5.7246 0.9998 221125_WJC_METTL3_EV_vs_WT_F07.10723.10723.2 0.000559 13/26 K.EQIVPKPEEEVAQK.K "sp|P18621|RL17_HUMAN,tr|J3QLC8|J3QLC8_HUMAN,tr|J3QQT2|J3QQT2_HUMAN,tr|A0A0A0MRF8|A0A0A0MRF8_HUMAN,tr|J3KRX5|J3KRX5_HUMAN,tr|A0A087WXM6|A0A087WXM6_HUMAN,tr|A0A0A6YYL6|A0A0A6YYL6_HUMAN" 7 1622.8516 1.05 98535 10723 2 1622.851637 812.4331 60S ribosomal protein L17 OS=Homo sapiens OX=9606 GN=RPL17 PE=1 SV=3 4.49 2117.8 - 835324 - - - 0.0524 - 1.897 0.476 - 248.4 1 2 0 0.0001 14 0 0 0 7.55E+07 7.20E+07 - - - 4.1634 0.9985 221125_WJC_METTL3_EV_vs_WT_F07.10724.10724.2 2.08E-05 24-Oct R.EDLQLDK[136.11]PASGVK[136.11].E "sp|P78347|GTF2I_HUMAN,tr|A0A494C0Q7|A0A494C0Q7_HUMAN,tr|A0A494C1K3|A0A494C1K3_HUMAN" 3 1414.7639 0.98 98536 10724 2 1414.757568 708.3892 General transcription factor II-I OS=Homo sapiens OX=9606 GN=GTF2I PE=1 SV=2 4.56 2118 - 196952 - - - -4.4467 - 2.149 0.531 - 367.6 1 2 0 -0.0063 13 0 0 0 3.49E+06 3.55E+06 - - - 4.9244 0.9997 221125_WJC_METTL3_EV_vs_WT_F07.10728.10728.2 0.00906 18-Oct K.KFWETDESSK.D "sp|Q14671|PUM1_HUMAN,tr|Q5T1Z8|Q5T1Z8_HUMAN,tr|H0YEH2|H0YEH2_HUMAN,tr|Q5T1Z4|Q5T1Z4_HUMAN" 4 1255.5721 2.83 98538 10728 2 1255.570165 628.7933 Pumilio homolog 1 OS=Homo sapiens OX=9606 GN=PUM1 PE=1 SV=3 4.68 2118.4 - 553469 - - - -1.5268 - 2.128 0.43 - 282.9 1 2 0 -0.0019 10 0 0 0 9.81E+06 3.46E+06 - - - 4.3243 0.9816 221125_WJC_METTL3_EV_vs_WT_F07.10729.10729.2 5.76E-08 28-Dec R.SDSPVPTAPTSGGPK[136.11].P "sp|Q86U44|MTA70_HUMAN,tr|B4E349|B4E349_HUMAN,tr|F5H6D8|F5H6D8_HUMAN,tr|B4DTN4|B4DTN4_HUMAN" 4 1404.6976 0.12 98539 10729 2 1404.694054 703.3561 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 5.55 2118.5 - 385020 - - - -2.5415 - 2.076 0.602 - 295.4 1 1 0 -0.0036 15 0 0 0 2.02E+06 1.68E+07 - - - 5.2821 0.9871 221125_WJC_METTL3_EV_vs_WT_F07.10730.10730.3 0.0326 Nov-48 R.EDLQLDKPASGVK.E "sp|P78347|GTF2I_HUMAN,tr|A0A494C0Q7|A0A494C0Q7_HUMAN,tr|A0A494C1K3|A0A494C1K3_HUMAN" 3 1398.7355 1.36 98540 10730 3 1398.735536 467.2524 General transcription factor II-I OS=Homo sapiens OX=9606 GN=GTF2I PE=1 SV=2 4.56 2118.6 - 5.95E+06 - - - 0.055 - 1.566 0.17 - 150.9 1 2 0 0.0001 13 0 0 0 6.65E+07 4.89E+07 - - - 1.6514 0.9999 221125_WJC_METTL3_EV_vs_WT_F07.10731.10731.3 0.00198 16/48 K.KLDEAVAEAHLGK.L sp|P23526|SAHH_HUMAN 1 1379.7409 1.94 98541 10731 3 1379.740385 460.9209 Adenosylhomocysteinase OS=Homo sapiens OX=9606 GN=AHCY PE=1 SV=4 5.45 2118.6 - 3.59E+06 - - - -0.358 - 2.619 0.411 - 285.4 1 2 0 -0.0005 13 0 0 0 8.90E+07 4.60E+07 - - - 5.7325 1 221125_WJC_METTL3_EV_vs_WT_F07.10732.10732.3 3.82E-05 13/48 R.IQFK[136.11]PDDGTTPER[166.11].L "sp|Q96AE4|FUBP1_HUMAN,tr|E9PEB5|E9PEB5_HUMAN" 2 1520.759 1.29 98542 10732 3 1520.758696 507.9269 Far upstream element-binding protein 1 OS=Homo sapiens OX=9606 GN=FUBP1 PE=1 SV=3 4.56 2118.7 - 2.59E+06 - - - -0.1946 - 2.357 0.505 - 179.5 1 2 0 -0.0003 13 0 0 0 1.33E+08 1.03E+08 - - - 6.4948 1 221125_WJC_METTL3_EV_vs_WT_F07.10733.10733.3 3.63E-06 14/64 R.AMIGHTDSAEAAPGTIR[166.11].G "sp|O00746|NDKM_HUMAN,tr|Q4TT34|Q4TT34_HUMAN,tr|A0A087WVT9|A0A087WVT9_HUMAN,tr|H0Y6J0|H0Y6J0_HUMAN,tr|F2Z2X0|F2Z2X0_HUMAN" 5 1706.8285 2.53 98543 10733 3 1706.825517 569.9501 "Nucleoside diphosphate kinase, mitochondrial OS=Homo sapiens OX=9606 GN=NME4 PE=1 SV=1" 5.32 2118.7 - 2.22E+06 - - - -1.7705 - 2.917 0.619 - 170.5 1 2 0 -0.003 17 0 0 0 8.16E+07 3.23E+07 - - - 8.1449 0.9997 221125_WJC_METTL3_EV_vs_WT_F07.10734.10734.3 6.94E-08 16/68 R.VLEQAEGK[136.11]VEEPENPAAK[136.11].E sp|Q9P2D1|CHD7_HUMAN 1 1953.0026 1.79 98544 10734 3 1952.998086 652.0081 Chromodomain-helicase-DNA-binding protein 7 OS=Homo sapiens OX=9606 GN=CHD7 PE=1 SV=3 4.33 2118.9 - 1.40E+06 - - - -2.3041 - 2.689 0.492 - 214.1 1 2 1 -0.0045 18 0 0 0 4.98E+07 2.79E+07 - - - 6.4872 0.978 221125_WJC_METTL3_EV_vs_WT_F07.10740.10740.3 0.292 Jul-40 R.SQYEQLAEQNR.K "sp|P13645|K1C10_HUMAN,tr|A0A1B0GVI3|A0A1B0GVI3_HUMAN" 2 1364.6321 17.27 98548 10740 3 1364.631383 455.8846 "Keratin, type I cytoskeletal 10 OS=Homo sapiens OX=9606 GN=KRT10 PE=1 SV=6" 4.53 2119.6 - 962006 - - - -0.4939 - 1.549 0.159 - 48.5 3 2 0 -0.0007 11 0 0 0 4.68E+07 2.71E+06 - - - 1.3349 0.9998 221125_WJC_METTL3_EV_vs_WT_F07.10748.10748.3 0.00599 13/60 K.QALLNEHGAAQEQLNK.L sp|O75330|HMMR_HUMAN 1 1762.8962 1.42 98554 10748 3 1762.896062 588.6393 Hyaluronan mediated motility receptor OS=Homo sapiens OX=9606 GN=HMMR PE=1 SV=2 5.4 2120.6 - 1.00E+06 - - - -0.0845 - 2.458 0.317 - 168.3 1 2 0 -0.0001 16 0 0 0 1.36E+07 9.63E+06 - - - 4.3818 0.9999 221125_WJC_METTL3_EV_vs_WT_F07.10750.10750.3 5.54E-06 Dec-56 K.QGTFHSQQALEYGTK.L "sp|P53597|SUCA_HUMAN,tr|A0A494C0D1|A0A494C0D1_HUMAN" 2 1693.806 2.19 98556 10750 3 1693.804106 565.6093 "Succinate--CoA ligase [ADP\GDP-forming] subunit alpha, mitochondrial OS=Homo sapiens OX=9606 GN=SUCLG1 PE=1 SV=4" 6.75 2120.7 - 9.50E+06 - - - -1.1176 - 2.497 0.439 - 249.9 1 2 0 -0.0019 15 0 0 0 2.36E+08 1.08E+08 - - - 5.8217 1 221125_WJC_METTL3_EV_vs_WT_F07.10755.10755.3 5.16E-06 13/44 R.RLDQC[160.03]PESPLQR.C sp|Q5T749|KPRP_HUMAN 1 1497.7358 0.64 98560 10755 3 1497.735713 500.2525 Keratinocyte proline-rich protein OS=Homo sapiens OX=9606 GN=KPRP PE=1 SV=1 6.06 2121.3 - 1.48E+06 - - - -0.0654 - 2.465 0.483 - 269.2 1 2 0 -0.0001 12 0 0 0 5.99E+07 9.29E+07 - - - 6.4257 0.9993 221125_WJC_METTL3_EV_vs_WT_F07.10756.10756.3 0.00587 Jul-40 R.HPGSFDVVHVK[136.11].D "sp|P62701|RS4X_HUMAN,sp|P22090|RS4Y1_HUMAN,tr|C9JEH7|C9JEH7_HUMAN" 3 1228.6444 1.01 98561 10756 3 1228.643385 410.5554 "40S ribosomal protein S4, X isoform OS=Homo sapiens OX=9606 GN=RPS4X PE=1 SV=2" 6.92 2121.4 - 183053 - - - -0.831 - 1.574 0.365 - 44 4 2 0 -0.001 11 0 0 0 5.91E+08 5.87E+08 - - - 3.6191 0.9998 221125_WJC_METTL3_EV_vs_WT_F07.10760.10760.2 4.00E-06 13/28 K.QGTFHSQQALEYGTK.L "sp|P53597|SUCA_HUMAN,tr|A0A494C0D1|A0A494C0D1_HUMAN" 2 1693.806 2.26 98565 10760 2 1693.802543 847.9103 "Succinate--CoA ligase [ADP\GDP-forming] subunit alpha, mitochondrial OS=Homo sapiens OX=9606 GN=SUCLG1 PE=1 SV=4" 6.75 2121.9 - 420566 - - - -2.0404 - 2.613 0.55 - 494.9 1 2 0 -0.0035 15 0 0 0 7.41E+06 3.28E+06 - - - 5.4636 0.9996 221125_WJC_METTL3_EV_vs_WT_F07.10762.10762.2 2.96E-05 28-Jul K.QGTFHSQQALEYGTK[136.11].L "sp|P53597|SUCA_HUMAN,tr|A0A494C0D1|A0A494C0D1_HUMAN" 2 1701.8202 2.26 98567 10762 2 1701.824082 851.9174 "Succinate--CoA ligase [ADP\GDP-forming] subunit alpha, mitochondrial OS=Homo sapiens OX=9606 GN=SUCLG1 PE=1 SV=4" 6.75 2122.2 - 268310 - - - 2.2817 - 1.872 0.556 - 135.4 1 2 0 0.0039 15 0 0 0 7.41E+06 3.28E+06 - - - 4.6879 1 221125_WJC_METTL3_EV_vs_WT_F07.10766.10766.3 9.94E-06 16/48 K.K[136.11]LDEAVAEAHLGK[136.11].L sp|P23526|SAHH_HUMAN 1 1395.7693 1.93 98569 10766 3 1395.768329 466.2637 Adenosylhomocysteinase OS=Homo sapiens OX=9606 GN=AHCY PE=1 SV=4 5.45 2122.6 - 2.52E+06 - - - -0.6806 - 2.921 0.46 - 495.2 1 2 0 -0.0009 13 0 0 0 8.82E+07 4.57E+07 - - - 6.5746 1 221125_WJC_METTL3_EV_vs_WT_F07.10769.10769.2 3.47E-07 13/20 K.GQTHTLEDFQR.V "sp|Q99714|HCD2_HUMAN,tr|Q5H928|Q5H928_HUMAN,tr|A0A804HHW5|A0A804HHW5_HUMAN" 3 1330.6266 0.51 98572 10769 2 1330.62507 666.3206 3-hydroxyacyl-CoA dehydrogenase type-2 OS=Homo sapiens OX=9606 GN=HSD17B10 PE=1 SV=3 5.32 2123 - 566676 - - - -1.1333 - 2.604 0.561 - 863.1 1 2 0 -0.0015 11 0 0 0 4.76E+06 9.40E+06 - - - 5.7731 1 221125_WJC_METTL3_EV_vs_WT_F07.10770.10770.2 1.77E-10 13/32 R.LPPNTNDEVDEDPTGNK[136.11].A sp|Q15393|SF3B3_HUMAN 1 1861.8421 1.43 98573 10770 2 1861.839606 931.9283 Splicing factor 3B subunit 3 OS=Homo sapiens OX=9606 GN=SF3B3 PE=1 SV=4 3.77 2123.1 - 496390 - - - -1.3481 - 2.373 0.689 - 294.1 1 2 0 -0.0025 17 0 0 0 1.97E+07 1.38E+07 - - - 6.2537 0.9991 221125_WJC_METTL3_EV_vs_WT_F07.10773.10773.2 0.0016 28-Aug R.DGTQC[160.03]LSGSSDGTIR[166.11].L sp|Q8TAF3|WDR48_HUMAN 1 1562.687 0.62 98576 10773 2 1562.683988 782.3508 WD repeat-containing protein 48 OS=Homo sapiens OX=9606 GN=WDR48 PE=1 SV=1 4.21 2123.5 - 295826 - - - -1.9396 - 1.521 0.423 - 91.6 1 2 0 -0.003 15 0 0 0 2.68E+06 4.30E+06 - - - 3.1954 0.999 221125_WJC_METTL3_EV_vs_WT_F07.10775.10775.3 0.162 Dec-44 K.KNYQSQADIPIR.S sp|Q14966|ZN638_HUMAN 1 1431.747 20.59 98577 10775 3 1431.747873 478.2563 Zinc finger protein 638 OS=Homo sapiens OX=9606 GN=ZNF638 PE=1 SV=2 8.59 2123.7 - 516033 - - - 0.5909 - 2.159 0.237 - 237.1 1 2 0 0.0008 12 0 0 0 2.84E+07 1.38E+06 - - - 3.3154 0.9999 221125_WJC_METTL3_EV_vs_WT_F07.10778.10778.3 4.87E-05 18/40 R.RIDISPSTLRK.H "sp|Q9NYF8|BCLF1_HUMAN,tr|E9PKI6|E9PKI6_HUMAN,tr|A0A1W2PQ43|A0A1W2PQ43_HUMAN,tr|E9PK91|E9PK91_HUMAN,tr|E9PK09|E9PK09_HUMAN,tr|E9PQN2|E9PQN2_HUMAN" 6 1284.7514 1.94 98579 10778 3 1284.751869 429.2577 Bcl-2-associated transcription factor 1 OS=Homo sapiens OX=9606 GN=BCLAF1 PE=1 SV=2 10.84 2124 - 2.05E+06 - - - 0.3775 - 3.13 0.336 - 623.3 1 2 0 0.0005 11 0 0 0 7.63E+07 3.94E+07 - - - 5.5274 1 221125_WJC_METTL3_EV_vs_WT_F07.10788.10788.3 0.000161 14/48 R.QASVADYEETVKK.A "sp|P49419|AL7A1_HUMAN,tr|H0YHM6|H0YHM6_HUMAN,tr|A0A1B0GUA1|A0A1B0GUA1_HUMAN,tr|A0A1B0GTG2|A0A1B0GTG2_HUMAN,tr|A0A1B0GW82|A0A1B0GW82_HUMAN,tr|A0A1B0GW77|A0A1B0GW77_HUMAN,tr|A0A1B0GTY9|A0A1B0GTY9_HUMAN,tr|A0A0J9YWF7|A0A0J9YWF7_HUMAN,tr|F8WDY6|F8WDY6_HUMAN" 9 1466.7253 0.75 98587 10788 3 1466.724849 489.9157 Alpha-aminoadipic semialdehyde dehydrogenase OS=Homo sapiens OX=9606 GN=ALDH7A1 PE=1 SV=5 4.68 2125.2 - 1.28E+06 - - - -0.3 - 2.672 0.501 - 246 1 2 0 -0.0004 13 0 0 0 2.32E+07 3.11E+07 - - - 6.7903 0.9998 221125_WJC_METTL3_EV_vs_WT_F07.10790.10790.3 0.000404 14/36 K.YKDAIHFYNK.S sp|P31948|STIP1_HUMAN 1 1297.6455 0.9 98589 10790 3 1297.647323 433.5558 Stress-induced-phosphoprotein 1 OS=Homo sapiens OX=9606 GN=STIP1 PE=1 SV=1 8.44 2125.3 - 1.08E+06 - - - 1.3879 - 2.549 0.452 - 178.7 1 2 1 0.0018 10 0 0 0 2.33E+07 2.59E+07 - - - 6.3115 0.9999 221125_WJC_METTL3_EV_vs_WT_F07.10792.10792.3 7.38E-09 15/48 K.FWETDESSK[136.11]DGPK[136.11].G "sp|Q14671|PUM1_HUMAN,tr|Q5T1Z8|Q5T1Z8_HUMAN,tr|H0YEH2|H0YEH2_HUMAN,tr|Q5T1Z4|Q5T1Z4_HUMAN" 4 1540.7017 2.62 98591 10792 3 1540.699591 514.5745 Pumilio homolog 1 OS=Homo sapiens OX=9606 GN=PUM1 PE=1 SV=3 4.32 2125.5 - 819244 - - - -1.3384 - 3.255 0.536 - 240.9 1 2 1 -0.0021 13 0 0 0 7.67E+07 2.92E+07 - - - 7.7151 1 221125_WJC_METTL3_EV_vs_WT_F07.10798.10798.3 3.69E-07 14/64 R.LPPNTNDEVDEDPTGNK.A sp|Q15393|SF3B3_HUMAN 1 1853.8279 0.91 98595 10798 3 1853.831521 618.9499 Splicing factor 3B subunit 3 OS=Homo sapiens OX=9606 GN=SF3B3 PE=1 SV=4 3.77 2126.2 - 668505 - - - 1.9446 - 2.587 0.548 - 175.5 1 2 0 0.0036 17 0 0 0 1.13E+07 1.24E+07 - - - 7.0499 0.9797 221125_WJC_METTL3_EV_vs_WT_F07.10801.10801.3 0.954 Sep-40 R.R[166.11]IDISPSTLR[166.11]K[136.11].H "sp|Q9NYF8|BCLF1_HUMAN,tr|E9PKI6|E9PKI6_HUMAN,tr|A0A1W2PQ43|A0A1W2PQ43_HUMAN,tr|E9PK91|E9PK91_HUMAN,tr|E9PK09|E9PK09_HUMAN,tr|E9PQN2|E9PQN2_HUMAN" 6 1312.7821 1.96 98596 10801 3 1312.781898 438.6013 Bcl-2-associated transcription factor 1 OS=Homo sapiens OX=9606 GN=BCLAF1 PE=1 SV=2 10.84 2126.6 - 1.81E+06 - - - -0.1722 - 1.733 0.115 - 107.6 1 2 0 -0.0002 11 0 0 0 7.74E+07 3.95E+07 - - - 1.3841 0.9998 221125_WJC_METTL3_EV_vs_WT_F07.10802.10802.3 0.0187 17/64 R.VGMVETNSQDR[166.11]PVDDVK[136.11].L sp|Q9Y3C6|PPIL1_HUMAN 1 1905.9221 1.08 98597 10802 3 1905.915238 636.3146 Peptidyl-prolyl cis-trans isomerase-like 1 OS=Homo sapiens OX=9606 GN=PPIL1 PE=1 SV=1 4.23 2126.7 - 715685 - - - -3.6061 - 2.976 0.472 - 361.4 1 2 0 -0.0069 17 0 0 0 2.43E+07 2.26E+07 - - - 6.5556 1 221125_WJC_METTL3_EV_vs_WT_F07.10805.10805.3 5.54E-08 15/56 R.EDC[160.03]SPADKPYIDEAR.R sp|Q96DG6|CMBL_HUMAN 1 1764.7625 1.33 98600 10805 3 1764.767104 589.2614 Carboxymethylenebutenolidase homolog OS=Homo sapiens OX=9606 GN=CMBL PE=1 SV=1 4.11 2127 - 345158 - - - 2.6207 - 3.008 0.636 - 275.4 1 2 0 0.0046 15 0 0 0 1.25E+07 9.40E+06 - - - 8.5031 0.9997 221125_WJC_METTL3_EV_vs_WT_F07.10813.10813.3 0.00583 13/44 K.LDLR[166.11]DDK[136.11]DTIER[166.11].L "sp|P60763|RAC3_HUMAN,tr|J3KSC4|J3KSC4_HUMAN,tr|J3QLK0|J3QLK0_HUMAN" 3 1515.7887 0.99 98606 10813 3 1515.789835 506.2702 Ras-related C3 botulinum toxin substrate 3 OS=Homo sapiens OX=9606 GN=RAC3 PE=1 SV=1 4.36 2127.9 - 491168 - - - 0.7316 - 2.526 0.392 - 365.9 1 2 2 0.0011 12 0 0 0 1.00E+07 1.01E+07 - - - 5.4786 0.9999 221125_WJC_METTL3_EV_vs_WT_F07.10814.10814.3 1.83E-05 Nov-60 K.ATAGDTHLGGEDFDNR[166.11].L "sp|P48741|HSP77_HUMAN,sp|P0DMV8|HS71A_HUMAN,sp|P34931|HS71L_HUMAN,sp|P0DMV9|HS71B_HUMAN,sp|P17066|HSP76_HUMAN,tr|Q53FA3|Q53FA3_HUMAN,tr|V9GZ37|V9GZ37_HUMAN,tr|A0A0G2JIW1|A0A0G2JIW1_HUMAN" 8 1684.7317 0.15 98607 10814 3 1684.733683 562.5845 Putative heat shock 70 kDa protein 7 OS=Homo sapiens OX=9606 GN=HSPA7 PE=5 SV=2 4.22 2128 - 775477 - - - 1.2002 - 1.992 0.484 - 141.2 1 2 0 0.002 16 0 0 0 3.47E+08 2.26E+09 - - - 5.7038 0.9976 221125_WJC_METTL3_EV_vs_WT_F07.10816.10816.2 0.000137 24-Nov K.FWETDESSKDGPK.G "sp|Q14671|PUM1_HUMAN,tr|Q5T1Z8|Q5T1Z8_HUMAN,tr|H0YEH2|H0YEH2_HUMAN,tr|Q5T1Z4|Q5T1Z4_HUMAN" 4 1524.6733 2.58 98609 10816 2 1524.675724 763.3439 Pumilio homolog 1 OS=Homo sapiens OX=9606 GN=PUM1 PE=1 SV=3 4.32 2128.2 - 285065 - - - 1.6207 - 2.102 0.541 - 328.1 1 2 1 0.0025 13 0 0 0 5.33E+06 2.06E+06 - - - 4.9427 0.9997 221125_WJC_METTL3_EV_vs_WT_F07.10822.10822.3 3.00E-05 Nov-52 R.MEEKDYTVTQVPPK.H "sp|Q8N5Z5|KCD17_HUMAN,tr|A0A087WX35|A0A087WX35_HUMAN,tr|H0Y731|H0Y731_HUMAN" 3 1663.8127 5.4 98614 10822 3 1663.81329 555.6115 BTB\POZ domain-containing protein KCTD17 OS=Homo sapiens OX=9606 GN=KCTD17 PE=1 SV=3 4.68 2129 - 1.04E+06 - - - 0.3402 - 1.936 0.466 - 110 1 2 1 0.0006 14 0 0 0 2.14E+07 3.97E+06 - - - 5.4909 0.9999 221125_WJC_METTL3_EV_vs_WT_F07.10831.10831.2 1.10E-07 13/32 K.SVEEPTQPGGTGLSDSR.T sp|Q9H0B6|KLC2_HUMAN 1 1715.7962 2.59 98622 10831 2 1715.796888 858.9054 Kinesin light chain 2 OS=Homo sapiens OX=9606 GN=KLC2 PE=1 SV=1 4.14 2129.9 - 246715 - - - 0.3882 - 2.772 0.564 - 301.8 1 2 0 0.0007 17 0 0 0 7.07E+06 2.73E+06 - - - 5.7132 0.9931 221125_WJC_METTL3_EV_vs_WT_F07.10833.10833.2 0.000842 24-Jul K.FWETDESSK[136.11]DGPK[136.11].G "sp|Q14671|PUM1_HUMAN,tr|Q5T1Z8|Q5T1Z8_HUMAN,tr|H0YEH2|H0YEH2_HUMAN,tr|Q5T1Z4|Q5T1Z4_HUMAN" 4 1540.7017 2.58 98624 10833 2 1540.703442 771.3581 Pumilio homolog 1 OS=Homo sapiens OX=9606 GN=PUM1 PE=1 SV=3 4.32 2130.2 - 140800 - - - 1.1612 - 1.669 0.382 - 125.3 1 2 1 0.0018 13 0 0 0 5.33E+06 2.06E+06 - - - 3.1765 0.9996 221125_WJC_METTL3_EV_vs_WT_F07.10834.10834.2 7.46E-06 Sep-32 K.SVEEPTQPGGTGLSDSR[166.11].T sp|Q9H0B6|KLC2_HUMAN 1 1725.8045 2.59 98625 10834 2 1725.809487 863.9095 Kinesin light chain 2 OS=Homo sapiens OX=9606 GN=KLC2 PE=1 SV=1 4.14 2130.3 - 119057 - - - 2.8943 - 2.098 0.614 - 132.6 1 2 0 0.005 17 0 0 0 7.07E+06 2.73E+06 - - - 5.3962 1 221125_WJC_METTL3_EV_vs_WT_F07.10837.10837.3 9.37E-06 18/64 R.VGMVETNSQDRPVDDVK.L sp|Q9Y3C6|PPIL1_HUMAN 1 1887.8996 1.05 98626 10837 3 1887.899814 630.3072 Peptidyl-prolyl cis-trans isomerase-like 1 OS=Homo sapiens OX=9606 GN=PPIL1 PE=1 SV=1 4.23 2130.8 - 2.93E+06 - - - 0.0916 - 3.263 0.559 - 436.1 1 2 0 0.0002 17 0 0 0 2.55E+07 2.43E+07 - - - 7.76 0.9999 221125_WJC_METTL3_EV_vs_WT_F07.10838.10838.3 0.00042 Nov-44 R.SRTEAESWYQTK.Y "sp|P13647|K2C5_HUMAN,tr|H0YI76|H0YI76_HUMAN,tr|H0YIN9|H0YIN9_HUMAN" 3 1484.6896 662.86 98627 10838 3 1484.689988 495.9038 "Keratin, type II cytoskeletal 5 OS=Homo sapiens OX=9606 GN=KRT5 PE=1 SV=3" 5.86 2130.8 - 1.78E+06 - - - 0.2802 - 2.688 0.524 - 244.1 1 2 1 0.0004 12 0 0 0 5.36E+08 8.09E+05 - - - 7.1228 0.9999 221125_WJC_METTL3_EV_vs_WT_F07.10839.10839.3 7.75E-05 Oct-44 R.NHLLESEDSYTR.E "sp|Q15643|TRIPB_HUMAN,tr|H0YJI2|H0YJI2_HUMAN,tr|H0YJ97|H0YJ97_HUMAN" 3 1462.6688 1.07 98628 10839 3 1462.668479 488.5636 Thyroid receptor-interacting protein 11 OS=Homo sapiens OX=9606 GN=TRIP11 PE=1 SV=3 4.65 2130.9 - 1.07E+06 - - - -0.2441 - 2.123 0.438 - 240 1 2 0 -0.0004 12 0 0 0 1.74E+07 1.63E+07 - - - 5.5099 0.9999 221125_WJC_METTL3_EV_vs_WT_F07.10840.10840.3 0.00752 15/44 R.K[136.11]DPGVPNSAPFK[136.11].E "sp|Q9BVP2|GNL3_HUMAN,tr|C9JYH9|C9JYH9_HUMAN,tr|B4DMU5|B4DMU5_HUMAN,tr|C9JZT7|C9JZT7_HUMAN" 4 1271.6845 1.35 98629 10840 3 1271.68194 424.9021 Guanine nucleotide-binding protein-like 3 OS=Homo sapiens OX=9606 GN=GNL3 PE=1 SV=2 8.59 2131 - 743783 - - - -2.0029 - 2.997 0.398 - 477.7 1 2 0 -0.0025 12 0 0 0 1.31E+07 9.70E+06 - - - 6.019 0.9999 221125_WJC_METTL3_EV_vs_WT_F07.10841.10841.2 6.24E-05 13/22 K.R[166.11]YDGSQQALDLK[136.11].G "sp|Q9UBU9|NXF1_HUMAN,tr|B4E227|B4E227_HUMAN,tr|E9PIN3|E9PIN3_HUMAN" 3 1410.7222 0.65 98630 10841 2 1410.722434 706.3684 Nuclear RNA export factor 1 OS=Homo sapiens OX=9606 GN=NXF1 PE=1 SV=1 5.96 2131.2 - 682971 - - - 0.1567 - 2.562 0.436 - 571.3 1 2 0 0.0002 12 0 0 0 6.19E+06 9.53E+06 - - - 4.7366 0.9999 221125_WJC_METTL3_EV_vs_WT_F07.10842.10842.3 0.000154 13/60 R.IQPEEKPVEVSPAVTK.G sp|Q8N0X7|SPART_HUMAN 1 1749.9513 1.39 98631 10842 3 1749.950279 584.3244 Spartin OS=Homo sapiens OX=9606 GN=SPART PE=1 SV=1 4.79 2131.3 - 668325 - - - -0.564 - 2.291 0.449 - 170.8 1 2 0 -0.001 16 0 0 0 1.92E+07 1.38E+07 - - - 5.6727 0.9726 221125_WJC_METTL3_EV_vs_WT_F07.10843.10843.3 0.165 Jul-60 K.STAGDTHLGGEDFDNR[166.11].M "sp|P54652|HSP72_HUMAN,sp|P11142|HSP7C_HUMAN,tr|E9PKE3|E9PKE3_HUMAN,tr|E9PN89|E9PN89_HUMAN" 4 1700.7266 0.23 98632 10843 3 1700.725589 567.9161 Heat shock-related 70 kDa protein 2 OS=Homo sapiens OX=9606 GN=HSPA2 PE=1 SV=1 4.22 2131.4 - 1.17E+06 - - - -0.5803 - 1.387 0.164 - 49.1 1 2 0 -0.001 16 0 0 0 2.12E+06 9.26E+06 - - - 1.2076 1 221125_WJC_METTL3_EV_vs_WT_F07.10844.10844.2 1.14E-10 19/36 R.EGQGEGETQEAAAATAAAR.R "sp|P58107|EPIPL_HUMAN,sp|P58107|EPIPL_HUMAN,tr|A0A075B730|A0A075B730_HUMAN,tr|A0A075B730|A0A075B730_HUMAN" 4 1816.8187 1.9 98633 10844 2 1816.819125 909.4167 Epiplakin OS=Homo sapiens OX=9606 GN=EPPK1 PE=1 SV=3 4.09 2131.5 - 425330 - - - 0.2075 - 3.736 0.719 - 1372.4 1 2 0 0.0004 19 0 0 0 1.55E+07 8.14E+06 - - - 7.5918 1 221125_WJC_METTL3_EV_vs_WT_F07.10845.10845.2 6.17E-11 18/30 K.ATAGDTHLGGEDFDNR[166.11].L "sp|P48741|HSP77_HUMAN,sp|P0DMV8|HS71A_HUMAN,sp|P34931|HS71L_HUMAN,sp|P0DMV9|HS71B_HUMAN,sp|P17066|HSP76_HUMAN,tr|Q53FA3|Q53FA3_HUMAN,tr|V9GZ37|V9GZ37_HUMAN,tr|A0A0G2JIW1|A0A0G2JIW1_HUMAN" 8 1684.7317 0.14 98634 10845 2 1684.72853 843.3731 Putative heat shock 70 kDa protein 7 OS=Homo sapiens OX=9606 GN=HSPA7 PE=5 SV=2 4.22 2131.6 - 390174 - - - -1.8585 - 3.364 0.75 - 660.6 1 2 0 -0.0031 16 0 0 0 1.56E+07 1.15E+08 - - - 7.5621 1 221125_WJC_METTL3_EV_vs_WT_F07.10847.10847.2 2.19E-13 17/36 R.EGQGEGETQEAAAATAAAR[166.11].R "sp|P58107|EPIPL_HUMAN,sp|P58107|EPIPL_HUMAN,tr|A0A075B730|A0A075B730_HUMAN,tr|A0A075B730|A0A075B730_HUMAN" 4 1826.827 1.9 98636 10847 2 1826.83418 914.4208 Epiplakin OS=Homo sapiens OX=9606 GN=EPPK1 PE=1 SV=3 4.09 2131.9 - 238324 - - - 3.9205 - 3.739 0.639 - 1002.4 1 2 0 0.0072 19 0 0 0 1.55E+07 8.14E+06 - - - 7.0008 1 221125_WJC_METTL3_EV_vs_WT_F07.10849.10849.3 1.51E-06 15/48 K.FWETDESSKDGPK.G "sp|Q14671|PUM1_HUMAN,tr|Q5T1Z8|Q5T1Z8_HUMAN,tr|H0YEH2|H0YEH2_HUMAN,tr|Q5T1Z4|Q5T1Z4_HUMAN" 4 1524.6733 2.63 98637 10849 3 1524.673967 509.2317 Pumilio homolog 1 OS=Homo sapiens OX=9606 GN=PUM1 PE=1 SV=3 4.32 2132.1 - 5.36E+06 - - - 0.4683 - 2.929 0.613 - 221.9 1 2 1 0.0007 13 0 0 0 7.69E+07 2.92E+07 - - - 8.2879 1 221125_WJC_METTL3_EV_vs_WT_F07.10851.10851.3 1.03E-05 14/60 K.ATAGDTHLGGEDFDNR.L "sp|P48741|HSP77_HUMAN,sp|P0DMV8|HS71A_HUMAN,sp|P34931|HS71L_HUMAN,sp|P0DMV9|HS71B_HUMAN,sp|P17066|HSP76_HUMAN,tr|Q53FA3|Q53FA3_HUMAN,tr|V9GZ37|V9GZ37_HUMAN,tr|A0A0G2JIW1|A0A0G2JIW1_HUMAN" 8 1674.7234 0.15 98639 10851 3 1674.723757 559.2484 Putative heat shock 70 kDa protein 7 OS=Homo sapiens OX=9606 GN=HSPA7 PE=5 SV=2 4.22 2132.2 - 4.76E+06 - - - 0.2185 - 2.822 0.57 - 280.7 1 2 0 0.0004 16 0 0 0 3.47E+08 2.26E+09 - - - 7.5568 0.9999 221125_WJC_METTL3_EV_vs_WT_F07.10852.10852.2 3.30E-05 14/26 K.GDATVSYEDPPTAK.A "sp|Q01844|EWS_HUMAN,tr|B0QYK0|B0QYK0_HUMAN,tr|H7BY36|H7BY36_HUMAN,tr|A0A0D9SFL3|A0A0D9SFL3_HUMAN,tr|C9JGE3|C9JGE3_HUMAN" 5 1449.6624 0.7 98640 10852 2 1449.661822 725.8385 RNA-binding protein EWS OS=Homo sapiens OX=9606 GN=EWSR1 PE=1 SV=1 4.03 2132.3 - 1.33E+06 - - - -0.367 - 2.285 0.565 - 404.9 1 2 0 -0.0005 14 0 0 0 3.08E+07 4.39E+07 - - - 5.2876 1 221125_WJC_METTL3_EV_vs_WT_F07.10855.10855.3 8.32E-05 14/44 R.KDPGVPNSAPFK.E "sp|Q9BVP2|GNL3_HUMAN,tr|C9JYH9|C9JYH9_HUMAN,tr|B4DMU5|B4DMU5_HUMAN,tr|C9JZT7|C9JZT7_HUMAN" 4 1255.6561 1.34 98643 10855 3 1255.654916 419.5593 Guanine nucleotide-binding protein-like 3 OS=Homo sapiens OX=9606 GN=GNL3 PE=1 SV=2 8.59 2132.6 - 727077 - - - -0.9326 - 2.65 0.453 - 426.5 1 2 0 -0.0012 12 0 0 0 1.30E+07 9.70E+06 - - - 6.2915 0.9997 221125_WJC_METTL3_EV_vs_WT_F07.10856.10856.3 0.000103 Sep-40 K.TYKDEGNDYFK.E sp|O95801|TTC4_HUMAN 1 1378.6041 0.92 98644 10856 3 1378.604864 460.542 Tetratricopeptide repeat protein 4 OS=Homo sapiens OX=9606 GN=TTC4 PE=1 SV=3 4.56 2132.7 - 643723 - - - 0.5462 - 1.785 0.496 - 85.1 1 2 1 0.0008 11 0 0 0 8.59E+06 9.33E+06 - - - 5.7157 0.9998 221125_WJC_METTL3_EV_vs_WT_F07.10857.10857.2 0.000874 22-Oct K.RYDGSQQALDLK.G "sp|Q9UBU9|NXF1_HUMAN,tr|B4E227|B4E227_HUMAN,tr|E9PIN3|E9PIN3_HUMAN" 3 1392.6997 0.66 98645 10857 2 1392.698727 697.3571 Nuclear RNA export factor 1 OS=Homo sapiens OX=9606 GN=NXF1 PE=1 SV=1 5.96 2132.9 - 579729 - - - -0.7295 - 2.266 0.427 - 300.3 1 2 0 -0.001 12 0 0 0 6.19E+06 9.40E+06 - - - 4.3468 1 221125_WJC_METTL3_EV_vs_WT_F07.10858.10858.3 2.64E-10 15/48 R.RLDEC[160.03]EEAFQGTK.V "sp|P61289|PSME3_HUMAN,tr|K7ENH2|K7ENH2_HUMAN,tr|B3KQ25|B3KQ25_HUMAN,tr|K7ESG5|K7ESG5_HUMAN,tr|K9J957|K9J957_HUMAN,tr|K7EMD0|K7EMD0_HUMAN,tr|K7EKR3|K7EKR3_HUMAN,tr|K7EPX6|K7EPX6_HUMAN" 8 1581.7093 1.06 98646 10858 3 1581.70503 528.2437 Proteasome activator complex subunit 3 OS=Homo sapiens OX=9606 GN=PSME3 PE=1 SV=1 4.41 2133 - 506047 - - - -2.7129 - 3.258 0.557 - 464.5 1 2 0 -0.0043 13 0 0 0 3.95E+07 3.74E+07 - - - 7.9512 1 221125_WJC_METTL3_EV_vs_WT_F07.10861.10861.2 1.82E-09 19/26 T.AGDTHLGGEDFDNR[166.11].L "sp|P48741|HSP77_HUMAN,sp|P54652|HSP72_HUMAN,sp|P0DMV8|HS71A_HUMAN,sp|P34931|HS71L_HUMAN,sp|P11142|HSP7C_HUMAN,sp|P0DMV9|HS71B_HUMAN,sp|P17066|HSP76_HUMAN,tr|E9PKE3|E9PKE3_HUMAN,tr|E9PN89|E9PN89_HUMAN,tr|Q53FA3|Q53FA3_HUMAN,tr|V9GZ37|V9GZ37_HUMAN,tr|A0A0G2JIW1|A0A0G2JIW1_HUMAN" 12 1512.6469 0.08 98649 10861 2 1512.649399 757.3307 Putative heat shock 70 kDa protein 7 OS=Homo sapiens OX=9606 GN=HSPA7 PE=5 SV=2 4.22 2133.3 - 359654 - - - 1.6726 - 2.99 0.697 - 1132.7 1 1 0 0.0025 14 0 0 0 2.19E+06 2.70E+07 - - - 6.9368 0.9999 221125_WJC_METTL3_EV_vs_WT_F07.10866.10866.3 0.000219 Dec-60 R.IQPEEK[136.11]PVEVSPAVTK[136.11].G sp|Q8N0X7|SPART_HUMAN 1 1765.9797 1.39 98652 10866 3 1765.978048 589.6672 Spartin OS=Homo sapiens OX=9606 GN=SPART PE=1 SV=1 4.79 2133.9 - 1.32E+06 - - - -0.9162 - 2.242 0.403 - 172.4 1 2 0 -0.0016 16 0 0 0 1.92E+07 1.38E+07 - - - 5.1042 1 221125_WJC_METTL3_EV_vs_WT_F07.10867.10867.2 5.69E-07 15/22 R.SRTEAESWYQTK.Y "sp|P13647|K2C5_HUMAN,tr|H0YI76|H0YI76_HUMAN,tr|H0YIN9|H0YIN9_HUMAN" 3 1484.6896 999 98653 10867 2 1484.688977 743.3521 "Keratin, type II cytoskeletal 5 OS=Homo sapiens OX=9606 GN=KRT5 PE=1 SV=3" 5.86 2134.1 - 1.62E+06 - - - -0.4008 - 2.578 0.621 - 574.6 1 2 1 -0.0006 12 0 0 0 7.26E+07 0.00E+00 - - - 6.1193 1 221125_WJC_METTL3_EV_vs_WT_F07.10868.10868.3 5.76E-11 17/72 R.EGQGEGETQEAAAATAAAR.R "sp|P58107|EPIPL_HUMAN,sp|P58107|EPIPL_HUMAN,tr|A0A075B730|A0A075B730_HUMAN,tr|A0A075B730|A0A075B730_HUMAN" 4 1816.8187 1.87 98654 10868 3 1816.818372 606.6135 Epiplakin OS=Homo sapiens OX=9606 GN=EPPK1 PE=1 SV=3 4.09 2134.1 - 1.13E+06 - - - -0.207 - 2.518 0.663 - 234 1 2 0 -0.0004 19 0 0 0 1.21E+07 6.48E+06 - - - 8.2005 1 221125_WJC_METTL3_EV_vs_WT_F07.10869.10869.3 4.55E-06 14/40 M.SDTWSSIQAHK[136.11].K "sp|Q86U44|MTA70_HUMAN,tr|B4E349|B4E349_HUMAN,tr|F5H6D8|F5H6D8_HUMAN,tr|B4DTN4|B4DTN4_HUMAN" 4 1266.6084 0.03 98655 10869 3 1266.607824 423.2101 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 6.46 2134.2 - 1.07E+06 - - - -0.4666 - 2.517 0.557 - 350 1 2 0 -0.0006 11 0 0 0 1.07E+08 3.39E+09 - - - 7.3721 1 221125_WJC_METTL3_EV_vs_WT_F07.10873.10873.2 2.31E-11 18/30 K.ATAGDTHLGGEDFDNR.L "sp|P48741|HSP77_HUMAN,sp|P0DMV8|HS71A_HUMAN,sp|P34931|HS71L_HUMAN,sp|P0DMV9|HS71B_HUMAN,sp|P17066|HSP76_HUMAN,tr|Q53FA3|Q53FA3_HUMAN,tr|V9GZ37|V9GZ37_HUMAN,tr|A0A0G2JIW1|A0A0G2JIW1_HUMAN" 8 1674.7234 0.14 98659 10873 2 1674.722124 838.369 Putative heat shock 70 kDa protein 7 OS=Homo sapiens OX=9606 GN=HSPA7 PE=5 SV=2 4.22 2134.6 - 582175 - - - -0.7565 - 3.315 0.707 - 797.6 1 2 0 -0.0013 16 0 0 0 1.56E+07 1.15E+08 - - - 7.209 0.9982 221125_WJC_METTL3_EV_vs_WT_F07.10874.10874.4 0.00152 13/78 K.EIAVHIGDR[166.11]DNAVR[166.11].N sp|Q14008|CKAP5_HUMAN 1 1583.8283 1.17 98660 10874 4 1583.827451 396.9643 Cytoskeleton-associated protein 5 OS=Homo sapiens OX=9606 GN=CKAP5 PE=1 SV=3 5.38 2134.8 - 565341 - - - -0.5316 - 2.071 0.336 - 157 1 2 1 -0.0008 14 0 0 0 8.16E+06 6.97E+06 - - - 2.4153 0.9978 221125_WJC_METTL3_EV_vs_WT_F07.10875.10875.3 0.000364 14/56 A.TAGDTHLGGEDFDNR[166.11].L "sp|P48741|HSP77_HUMAN,sp|P54652|HSP72_HUMAN,sp|P0DMV8|HS71A_HUMAN,sp|P34931|HS71L_HUMAN,sp|P11142|HSP7C_HUMAN,sp|P0DMV9|HS71B_HUMAN,sp|P17066|HSP76_HUMAN,tr|E9PKE3|E9PKE3_HUMAN,tr|E9PN89|E9PN89_HUMAN,tr|Q53FA3|Q53FA3_HUMAN,tr|V9GZ37|V9GZ37_HUMAN,tr|A0A0G2JIW1|A0A0G2JIW1_HUMAN" 12 1613.6945 0.14 98661 10875 3 1613.693737 538.9055 Putative heat shock 70 kDa protein 7 OS=Homo sapiens OX=9606 GN=HSPA7 PE=5 SV=2 4.22 2134.9 - 432982 - - - -0.502 - 2.369 0.558 - 199.3 1 1 0 -0.0008 15 0 0 0 1.07E+06 7.56E+06 - - - 7.0114 0.8481 221125_WJC_METTL3_EV_vs_WT_F07.10876.10876.4 0.941 13/78 K.EIAVHIGDRDNAVR.N sp|Q14008|CKAP5_HUMAN 1 1563.8118 1.17 98662 10876 4 1563.813392 391.9602 Cytoskeleton-associated protein 5 OS=Homo sapiens OX=9606 GN=CKAP5 PE=1 SV=3 5.38 2135 - 393733 - - - 1.0481 - 1.728 0.143 - 176.9 1 2 1 0.0016 14 0 0 0 8.16E+06 6.97E+06 - - - 0.6693 0.9999 221125_WJC_METTL3_EV_vs_WT_F07.10880.10880.3 0.000217 15/52 K.EQIVPKPEEEVAQK.K "sp|P18621|RL17_HUMAN,tr|J3QLC8|J3QLC8_HUMAN,tr|J3QQT2|J3QQT2_HUMAN,tr|A0A0A0MRF8|A0A0A0MRF8_HUMAN,tr|J3KRX5|J3KRX5_HUMAN,tr|A0A087WXM6|A0A087WXM6_HUMAN,tr|A0A0A6YYL6|A0A0A6YYL6_HUMAN" 7 1622.8516 1.05 98665 10880 3 1622.852601 541.9578 60S ribosomal protein L17 OS=Homo sapiens OX=9606 GN=RPL17 PE=1 SV=3 4.49 2135.5 - 684305 - - - 0.6464 - 2.556 0.397 - 229.6 1 2 0 0.001 14 0 0 0 9.31E+08 8.84E+08 - - - 5.4598 1 221125_WJC_METTL3_EV_vs_WT_F07.10882.10882.3 1.20E-06 Oct-48 R.R[166.11]LDEC[160.03]EEAFQGTK[136.11].V "sp|P61289|PSME3_HUMAN,tr|K7ENH2|K7ENH2_HUMAN,tr|B3KQ25|B3KQ25_HUMAN,tr|K7ESG5|K7ESG5_HUMAN,tr|K9J957|K9J957_HUMAN,tr|K7EMD0|K7EMD0_HUMAN,tr|K7EKR3|K7EKR3_HUMAN,tr|K7EPX6|K7EPX6_HUMAN" 8 1599.7318 1.06 98666 10882 3 1599.731448 534.2512 Proteasome activator complex subunit 3 OS=Homo sapiens OX=9606 GN=PSME3 PE=1 SV=1 4.41 2135.7 - 2.94E+06 - - - -0.2144 - 2.362 0.571 - 211.7 1 2 0 -0.0003 13 0 0 0 3.95E+07 3.74E+07 - - - 7.2364 0.9995 221125_WJC_METTL3_EV_vs_WT_F07.10883.10883.3 0.0011 15/36 R.NKLDHYAIIK.F "sp|P62750|RL23A_HUMAN,tr|H7BY10|H7BY10_HUMAN,tr|K7ERT8|K7ERT8_HUMAN,tr|A8MUS3|A8MUS3_HUMAN,tr|K7EJV9|K7EJV9_HUMAN" 5 1213.6819 0.65 98667 10883 3 1213.679916 405.5679 60S ribosomal protein L23a OS=Homo sapiens OX=9606 GN=RPL23A PE=1 SV=1 8.51 2135.8 - 1.43E+06 - - - -1.6413 - 2.926 0.335 - 272.5 1 2 1 -0.002 10 0 0 0 6.11E+07 9.36E+07 - - - 5.4099 0.8649 221125_WJC_METTL3_EV_vs_WT_F07.10884.10884.4 1.31 May-84 Q.GSDPSGWEDC[160.03]SFDNR.L "sp|B2RTY4|MYO9A_HUMAN,tr|H3BMM1|H3BMM1_HUMAN,tr|H3BRD5|H3BRD5_HUMAN" 3 1727.6482 0.16 98668 10884 4 1727.635901 432.9193 Unconventional myosin-IXa OS=Homo sapiens OX=9606 GN=MYO9A PE=1 SV=2 3.84 2135.9 - 1.74E+06 - - - -7.1062 - 1.208 0.571 - 25.3 1 1 0 -0.0123 15 0 0 0 1.82E+07 1.16E+08 - - - 4.2602 1 221125_WJC_METTL3_EV_vs_WT_F07.10885.10885.3 6.88E-12 15/72 R.EGQGEGETQEAAAATAAAR[166.11].R "sp|P58107|EPIPL_HUMAN,sp|P58107|EPIPL_HUMAN,tr|A0A075B730|A0A075B730_HUMAN,tr|A0A075B730|A0A075B730_HUMAN" 4 1826.827 1.87 98669 10885 3 1826.82578 609.9496 Epiplakin OS=Homo sapiens OX=9606 GN=EPPK1 PE=1 SV=3 4.09 2136 - 828654 - - - -0.6777 - 2.98 0.669 - 288.6 1 2 0 -0.0012 19 0 0 0 1.21E+07 6.48E+06 - - - 8.681 1 221125_WJC_METTL3_EV_vs_WT_F07.10886.10886.3 1.25E-05 14/48 R.NALANQSDC[160.03]VLHR.L "sp|Q9UJX3|APC7_HUMAN,tr|H0YIW2|H0YIW2_HUMAN" 2 1496.7154 1.17 98670 10886 3 1496.713186 499.9124 Anaphase-promoting complex subunit 7 OS=Homo sapiens OX=9606 GN=ANAPC7 PE=1 SV=4 6.74 2136.2 - 748114 - - - -1.4859 - 2.773 0.47 - 362.1 1 2 0 -0.0022 13 0 0 0 5.40E+06 4.60E+06 - - - 6.5447 0.9998 221125_WJC_METTL3_EV_vs_WT_F07.10888.10888.2 6.02E-08 26-Nov R.SGNYPSSLSNETDR[166.11].L sp|Q9NS86|LANC2_HUMAN 1 1535.6727 0.84 98672 10888 2 1535.669201 768.8437 LanC-like protein 2 OS=Homo sapiens OX=9606 GN=LANCL2 PE=1 SV=1 4.37 2136.4 - 398437 - - - -2.3104 - 2.243 0.592 - 239.4 1 2 0 -0.0035 14 0 0 0 2.83E+06 3.37E+06 - - - 5.4396 1 221125_WJC_METTL3_EV_vs_WT_F07.10891.10891.2 1.37E-07 15/26 K.GDATVSYEDPPTAK[136.11].A "sp|Q01844|EWS_HUMAN,tr|B0QYK0|B0QYK0_HUMAN,tr|H7BY36|H7BY36_HUMAN,tr|A0A0D9SFL3|A0A0D9SFL3_HUMAN,tr|C9JGE3|C9JGE3_HUMAN" 5 1457.6766 0.7 98674 10891 2 1457.675013 729.8456 RNA-binding protein EWS OS=Homo sapiens OX=9606 GN=EWSR1 PE=1 SV=1 4.03 2136.8 - 1.74E+06 - - - -1.0572 - 2.641 0.627 - 442.7 1 2 0 -0.0015 14 0 0 0 2.92E+07 4.18E+07 - - - 6.1086 0.9999 221125_WJC_METTL3_EV_vs_WT_F07.10897.10897.3 2.70E-06 Nov-32 R.LHIC[160.03]DHFTR.G "sp|Q7Z2W4|ZCCHV_HUMAN,tr|C9J6P4|C9J6P4_HUMAN,tr|A0A7P0T8C6|A0A7P0T8C6_HUMAN" 3 1197.5713 1.53 98679 10897 3 1197.571066 400.1977 Zinc finger CCCH-type antiviral protein 1 OS=Homo sapiens OX=9606 GN=ZC3HAV1 PE=1 SV=3 6.91 2137.3 - 991560 - - - -0.2054 - 2.324 0.398 - 218 1 2 0 -0.0002 9 0 0 0 2.23E+07 1.46E+07 - - - 5.5187 0.9999 221125_WJC_METTL3_EV_vs_WT_F07.10898.10898.3 2.19E-05 15/40 R.NR[166.11]DHDTFLAVR[166.11].Y "sp|Q12907|LMAN2_HUMAN,tr|D6RBV2|D6RBV2_HUMAN,tr|D6RDX1|D6RDX1_HUMAN,tr|D6RIU4|D6RIU4_HUMAN" 4 1362.6907 1.26 98680 10898 3 1362.688617 455.2375 Vesicular integral-membrane protein VIP36 OS=Homo sapiens OX=9606 GN=LMAN2 PE=1 SV=1 6.75 2137.4 - 909623 - - - -1.555 - 2.934 0.539 - 573.9 1 2 1 -0.0021 11 0 0 0 2.53E+07 2.01E+07 - - - 7.6065 1 221125_WJC_METTL3_EV_vs_WT_F07.10899.10899.3 3.88E-11 21/52 R.DHAVVVGVYR[166.11]PPPK[136.11].V sp|P22087|FBRL_HUMAN 1 1550.8688 0.59 98681 10899 3 1550.866668 517.9635 rRNA 2'-O-methyltransferase fibrillarin OS=Homo sapiens OX=9606 GN=FBL PE=1 SV=2 8.6 2137.6 - 799790 - - - -1.3857 - 3.473 0.538 - 704.1 1 2 0 -0.0021 14 0 0 0 8.57E+06 1.46E+07 - - - 7.8463 0.9999 221125_WJC_METTL3_EV_vs_WT_F07.10900.10900.3 0.000749 Dec-40 M.SDTWSSIQAHK.K "sp|Q86U44|MTA70_HUMAN,tr|B4E349|B4E349_HUMAN,tr|F5H6D8|F5H6D8_HUMAN,tr|B4DTN4|B4DTN4_HUMAN" 4 1258.5942 0.03 98682 10900 3 1258.592435 420.5387 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 6.46 2137.7 - 620537 - - - -1.4143 - 2.058 0.494 - 265.6 1 2 0 -0.0018 11 0 0 0 1.06E+08 3.39E+09 - - - 6.0974 1 221125_WJC_METTL3_EV_vs_WT_F07.10902.10902.2 0.00112 14/24 R.RLDEC[160.03]EEAFQGTK.V "sp|P61289|PSME3_HUMAN,tr|K7ENH2|K7ENH2_HUMAN,tr|B3KQ25|B3KQ25_HUMAN,tr|K7ESG5|K7ESG5_HUMAN,tr|K9J957|K9J957_HUMAN,tr|K7EMD0|K7EMD0_HUMAN,tr|K7EKR3|K7EKR3_HUMAN,tr|K7EPX6|K7EPX6_HUMAN" 8 1581.7093 0.92 98684 10902 2 1581.707271 791.8619 Proteasome activator complex subunit 3 OS=Homo sapiens OX=9606 GN=PSME3 PE=1 SV=1 4.41 2137.9 - 512671 - - - -1.2961 - 2.961 0.574 - 374.2 1 2 0 -0.0021 13 0 0 0 5.81E+06 6.28E+06 - - - 6.066 0.9998 221125_WJC_METTL3_EV_vs_WT_F07.10907.10907.3 0.000599 14/36 R.NK[136.11]LDHYAIIK[136.11].F "sp|P62750|RL23A_HUMAN,tr|H7BY10|H7BY10_HUMAN,tr|K7ERT8|K7ERT8_HUMAN,tr|A8MUS3|A8MUS3_HUMAN,tr|K7EJV9|K7EJV9_HUMAN" 5 1229.7103 0.65 98687 10907 3 1229.7092 410.9107 60S ribosomal protein L23a OS=Homo sapiens OX=9606 GN=RPL23A PE=1 SV=1 8.51 2138.5 - 5.55E+06 - - - -0.901 - 2.453 0.451 - 290 1 2 1 -0.0011 10 0 0 0 6.11E+07 9.36E+07 - - - 6.1884 0.9998 221125_WJC_METTL3_EV_vs_WT_F07.10908.10908.3 5.19E-05 Dec-48 K.LTRDETNYGIPQR.A "sp|P63244|RACK1_HUMAN,tr|D6RFX4|D6RFX4_HUMAN,tr|D6RFZ9|D6RFZ9_HUMAN,tr|D6RAU2|D6RAU2_HUMAN,tr|D6R9Z1|D6R9Z1_HUMAN,tr|D6R9L0|D6R9L0_HUMAN,tr|D6RHH4|D6RHH4_HUMAN,tr|D6RBD0|D6RBD0_HUMAN,tr|D6R909|D6R909_HUMAN,tr|D6RAC2|D6RAC2_HUMAN,tr|D6RGK8|D6RGK8_HUMAN,tr|E9PD14|E9PD14_HUMAN,tr|D6REE5|D6REE5_HUMAN" 13 1561.7849 1.04 98688 10908 3 1561.783524 521.6022 Receptor of activated protein C kinase 1 OS=Homo sapiens OX=9606 GN=RACK1 PE=1 SV=3 6.07 2138.6 - 1.81E+06 - - - -0.8612 - 2.669 0.463 - 196.2 1 2 1 -0.0013 13 0 0 0 6.30E+07 6.08E+07 - - - 6.3633 0.9999 221125_WJC_METTL3_EV_vs_WT_F07.10910.10910.3 0.000171 14/44 K.LDIPTGTTPQRK.S "sp|P52732|KIF11_HUMAN,tr|A0A7I2V3A9|A0A7I2V3A9_HUMAN" 2 1325.7303 3.88 98690 10910 3 1325.730618 442.9174 Kinesin-like protein KIF11 OS=Homo sapiens OX=9606 GN=KIF11 PE=1 SV=2 8.75 2138.7 - 2.23E+06 - - - 0.2293 - 2.549 0.418 - 332.3 1 2 0 0.0003 12 0 0 0 3.27E+08 8.42E+07 - - - 5.7938 0.9999 221125_WJC_METTL3_EV_vs_WT_F07.10911.10911.3 5.82E-05 13/48 K.NPSDSAVHSPFTK.R "sp|Q14157|UBP2L_HUMAN,tr|F8W726|F8W726_HUMAN" 2 1385.6575 2.37 98691 10911 3 1385.655879 462.8931 Ubiquitin-associated protein 2-like OS=Homo sapiens OX=9606 GN=UBAP2L PE=1 SV=2 6.74 2138.7 - 1.64E+06 - - - -1.2009 - 2.316 0.407 - 281.5 1 2 0 -0.0017 13 0 0 0 2.52E+09 1.07E+09 - - - 5.3542 1 221125_WJC_METTL3_EV_vs_WT_F07.10915.10915.3 1.46E-05 13/48 K.NNIDVC[160.03]PEC[160.03]GHLK.Q sp|Q9BYC8|RM32_HUMAN 1 1554.6919 1.33 98695 10915 3 1554.691687 519.2379 "39S ribosomal protein L32, mitochondrial OS=Homo sapiens OX=9606 GN=MRPL32 PE=1 SV=1" 5.32 2139.1 - 691227 - - - -0.1351 - 2.315 0.471 - 184.5 1 2 0 -0.0002 13 0 0 0 1.45E+07 1.09E+07 - - - 6.067 0.9984 221125_WJC_METTL3_EV_vs_WT_F07.10922.10922.3 0.000535 Oct-48 K.NPSDSAVHSPFTK[136.11].R "sp|Q14157|UBP2L_HUMAN,tr|F8W726|F8W726_HUMAN" 2 1393.6717 2.87 98700 10922 3 1393.677188 465.5645 Ubiquitin-associated protein 2-like OS=Homo sapiens OX=9606 GN=UBAP2L PE=1 SV=2 6.74 2140 - 1.04E+06 - - - 3.9069 - 1.907 0.38 - 141.6 1 2 0 0.0054 13 0 0 0 3.57E+09 1.24E+09 - - - 4.5253 0.9998 221125_WJC_METTL3_EV_vs_WT_F07.10923.10923.3 7.13E-07 14/48 K.LTR[166.11]DETNYGIPQR[166.11].A "sp|P63244|RACK1_HUMAN,tr|D6RFX4|D6RFX4_HUMAN,tr|D6RFZ9|D6RFZ9_HUMAN,tr|D6RAU2|D6RAU2_HUMAN,tr|D6R9Z1|D6R9Z1_HUMAN,tr|D6R9L0|D6R9L0_HUMAN,tr|D6RHH4|D6RHH4_HUMAN,tr|D6RBD0|D6RBD0_HUMAN,tr|D6R909|D6R909_HUMAN,tr|D6RAC2|D6RAC2_HUMAN,tr|D6RGK8|D6RGK8_HUMAN,tr|E9PD14|E9PD14_HUMAN,tr|D6REE5|D6REE5_HUMAN" 13 1581.8014 1.03 98701 10923 3 1581.802049 528.2744 Receptor of activated protein C kinase 1 OS=Homo sapiens OX=9606 GN=RACK1 PE=1 SV=3 6.07 2140 - 3.26E+06 - - - 0.4046 - 2.637 0.46 - 286.8 1 2 1 0.0006 13 0 0 0 6.33E+07 6.14E+07 - - - 6.2973 0.9885 221125_WJC_METTL3_EV_vs_WT_F07.10924.10924.2 5.87E-06 18-Oct S.DTWSSIQAHK[136.11].K "sp|Q86U44|MTA70_HUMAN,tr|B4E349|B4E349_HUMAN,tr|F5H6D8|F5H6D8_HUMAN,tr|B4DTN4|B4DTN4_HUMAN" 4 1179.5764 0.01 98702 10924 2 1179.575847 590.7955 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 6.74 2140.1 - 2.07E+06 - - - -0.4569 - 2.042 0.423 - 261.8 1 1 0 -0.0005 10 0 0 0 5.83E+05 5.69E+07 - - - 4.1579 0.9998 221125_WJC_METTL3_EV_vs_WT_F07.10927.10927.2 0.000205 18-Dec R.RQLDSIVGER.G "sp|P48668|K2C6C_HUMAN,sp|P13647|K2C5_HUMAN,sp|P02538|K2C6A_HUMAN,tr|F8W0C6|F8W0C6_HUMAN" 4 1171.6309 999 98705 10927 2 1171.629249 586.8227 "Keratin, type II cytoskeletal 6C OS=Homo sapiens OX=9606 GN=KRT6C PE=1 SV=3" 6.07 2140.4 - 573606 - - - -1.439 - 2.371 0.414 - 274 1 2 0 -0.0017 10 0 0 0 1.10E+07 0.00E+00 - - - 4.508 0.9998 221125_WJC_METTL3_EV_vs_WT_F07.10928.10928.2 1.32E-05 Aug-34 K.VAQPPLSAQATGSGQPTR[166.11].K "sp|Q86UK7|ZN598_HUMAN,tr|H3BR87|H3BR87_HUMAN,tr|H3BQQ2|H3BQQ2_HUMAN,tr|H3BPG6|H3BPG6_HUMAN" 4 1774.9201 0.6 98706 10928 2 1774.921602 888.4673 E3 ubiquitin-protein ligase ZNF598 OS=Homo sapiens OX=9606 GN=ZNF598 PE=1 SV=1 9.72 2140.6 - 191444 - - - 0.8288 - 1.94 0.563 - 75.5 1 2 0 0.0015 18 0 0 0 2.41E+06 4.05E+06 - - - 4.8281 0.9987 221125_WJC_METTL3_EV_vs_WT_F07.10931.10931.3 0.555 Dec-44 K.LDIPTGTTPQR[166.11]K[136.11].S "sp|P52732|KIF11_HUMAN,tr|A0A7I2V3A9|A0A7I2V3A9_HUMAN" 2 1343.7528 3.86 98707 10931 3 1343.750802 448.9249 Kinesin-like protein KIF11 OS=Homo sapiens OX=9606 GN=KIF11 PE=1 SV=2 8.75 2140.9 - 1.70E+06 - - - -1.475 - 2.152 0.238 - 271.9 1 2 0 -0.002 12 0 0 0 3.27E+08 8.47E+07 - - - 3.3173 0.9994 221125_WJC_METTL3_EV_vs_WT_F07.10932.10932.3 0.01 13/36 K.HSLNIGDYNR.T "sp|Q8NDV7|TNR6A_HUMAN,tr|H7C269|H7C269_HUMAN" 2 1187.5683 0.75 98708 10932 3 1187.565695 396.8634 Trinucleotide repeat-containing gene 6A protein OS=Homo sapiens OX=9606 GN=TNRC6A PE=1 SV=2 6.74 2141.1 - 1.16E+06 - - - -2.2222 - 1.936 0.341 - 264.5 1 2 0 -0.0026 10 0 0 0 1.67E+07 2.23E+07 - - - 4.2704 0.9997 221125_WJC_METTL3_EV_vs_WT_F07.10934.10934.2 9.13E-05 22-Sep K.LDIPTGTTPQRK.S "sp|P52732|KIF11_HUMAN,tr|A0A7I2V3A9|A0A7I2V3A9_HUMAN" 2 1325.7303 6.11 98710 10934 2 1325.730537 663.8724 Kinesin-like protein KIF11 OS=Homo sapiens OX=9606 GN=KIF11 PE=1 SV=2 8.75 2141.3 - 467453 - - - 0.1682 - 1.791 0.387 - 214.4 1 2 0 0.0002 12 0 0 0 2.86E+07 4.67E+06 - - - 3.4327 0.9682 221125_WJC_METTL3_EV_vs_WT_F07.10941.10941.3 0.00306 17/64 M.AEVDAAMAAR[166.11]PHSIDGR[166.11].V "sp|P22626|ROA2_HUMAN,tr|A0A7I2YQN4|A0A7I2YQN4_HUMAN,tr|A0A7I2V4N0|A0A7I2V4N0_HUMAN,tr|A0A024RA28|A0A024RA28_HUMAN,tr|A0A7I2V4N1|A0A7I2V4N1_HUMAN,tr|A0A7I2V4I6|A0A7I2V4I6_HUMAN,tr|A0A087WUI2|A0A087WUI2_HUMAN,tr|A0A7I2V4S4|A0A7I2V4S4_HUMAN,tr|A0A7I2V323|A0A7I2V323_HUMAN,tr|A0A7I2V3P1|A0A7I2V3P1_HUMAN,tr|A0A7I2V3P7|A0A7I2V3P7_HUMAN" 11 1785.8695 0.47 98714 10941 3 1785.86544 596.2971 Heterogeneous nuclear ribonucleoproteins A2\B1 OS=Homo sapiens OX=9606 GN=HNRNPA2B1 PE=1 SV=2 5.38 2142 - 992511 - - - -2.2768 - 2.705 0.342 - 370 1 1 0 -0.0041 17 0 0 0 1.65E+07 3.50E+07 - - - 4.8658 1 221125_WJC_METTL3_EV_vs_WT_F07.10942.10942.3 1.34E-05 15/48 K.SGNALFHASTLHR.L sp|Q14152|EIF3A_HUMAN 1 1409.7164 1.96 98715 10942 3 1409.715599 470.9127 Eukaryotic translation initiation factor 3 subunit A OS=Homo sapiens OX=9606 GN=EIF3A PE=1 SV=1 9.51 2142.1 - 1.63E+06 - - - -0.5654 - 2.63 0.494 - 314.1 1 2 0 -0.0008 13 0 0 0 7.17E+07 3.66E+07 - - - 6.6692 0.9998 221125_WJC_METTL3_EV_vs_WT_F07.10944.10944.2 1.66E-07 14/28 K.LSGWGNVSKPSGTTK.S "sp|Q6Y7W6|GGYF2_HUMAN,tr|A0A7I2V3H7|A0A7I2V3H7_HUMAN,tr|I1E4Y6|I1E4Y6_HUMAN,tr|A0A7I2V516|A0A7I2V516_HUMAN,tr|A0A7I2V3H0|A0A7I2V3H0_HUMAN,tr|A0A7I2V361|A0A7I2V361_HUMAN" 6 1517.7838 4.03 98717 10944 2 1517.78028 759.8992 GRB10-interacting GYF protein 2 OS=Homo sapiens OX=9606 GN=GIGYF2 PE=1 SV=1 10 2142.3 - 398510 - - - -2.3238 - 2.426 0.588 - 483.5 1 2 0 -0.0035 15 0 0 0 1.66E+07 4.13E+06 - - - 5.5617 0.9996 221125_WJC_METTL3_EV_vs_WT_F07.10948.10948.2 0.00138 22-Sep K.DGNLASTLGQHK[136.11].G "sp|Q9BZK7|TBL1R_HUMAN,sp|O60907|TBL1X_HUMAN,tr|A0A1B0GVH3|A0A1B0GVH3_HUMAN,tr|A0A804HJZ5|A0A804HJZ5_HUMAN,tr|A0A2R8YFW3|A0A2R8YFW3_HUMAN,tr|A0A0D9SF63|A0A0D9SF63_HUMAN" 6 1247.635 2.11 98719 10948 2 1247.637186 624.8248 F-box-like\WD repeat-containing protein TBL1XR1 OS=Homo sapiens OX=9606 GN=TBL1XR1 PE=1 SV=1 6.74 2142.9 - 381127 - - - 1.781 - 1.733 0.474 - 295.8 1 2 0 0.0022 12 0 0 0 1.77E+07 8.39E+06 - - - 3.988 0.9174 221125_WJC_METTL3_EV_vs_WT_F07.10949.10949.2 0.0128 12-Jul W.SSIQAHK[136.11].K "sp|Q86U44|MTA70_HUMAN,tr|B4E349|B4E349_HUMAN,tr|F5H6D8|F5H6D8_HUMAN,tr|B4DTN4|B4DTN4_HUMAN" 4 777.4225 0.04 98720 10949 2 777.420973 389.7185 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 8.49 2142.9 - 1.19E+06 - - - -1.9024 - 1.302 0.374 - 159 1 1 0 -0.0015 7 0 0 0 6.15E+05 1.65E+07 - - - 2.6391 0.9997 221125_WJC_METTL3_EV_vs_WT_F07.10951.10951.3 4.62E-05 14/48 K.EIESTK[136.11]GELSIQR[166.11].M sp|Q96EA4|SPDLY_HUMAN 1 1506.8009 1.43 98722 10951 3 1506.799763 503.2742 Protein Spindly OS=Homo sapiens OX=9606 GN=SPDL1 PE=1 SV=2 4.79 2143.2 - 370537 - - - -0.726 - 2.344 0.443 - 285.3 1 2 1 -0.0011 13 0 0 0 8.77E+06 6.14E+06 - - - 5.7883 1 221125_WJC_METTL3_EV_vs_WT_F07.10954.10954.3 8.92E-06 Nov-52 R.LLEGEDAHLTQYKK.E "sp|Q04695|K1C17_HUMAN,tr|A0A3B3IS58|A0A3B3IS58_HUMAN,tr|F5GWP8|F5GWP8_HUMAN" 3 1643.8519 47.73 98723 10954 3 1643.851638 548.9579 "Keratin, type I cytoskeletal 17 OS=Homo sapiens OX=9606 GN=KRT17 PE=1 SV=2" 5.45 2143.6 - 4.15E+06 - - - -0.1509 - 2.466 0.455 - 94.5 1 2 0 -0.0002 14 0 0 0 6.29E+08 1.32E+07 - - - 6.0114 0.9852 221125_WJC_METTL3_EV_vs_WT_F07.10955.10955.3 2.01E-06 15/60 K.IK[136.11]ELNNTC[160.03]EPVVTQPK[136.11].P "sp|Q92598|HS105_HUMAN,tr|Q5TBM3|Q5TBM3_HUMAN,tr|A0A0A0MSM0|A0A0A0MSM0_HUMAN" 3 1884.995 0.04 98724 10955 3 1884.991319 629.3389 Heat shock protein 105 kDa OS=Homo sapiens OX=9606 GN=HSPH1 PE=1 SV=1 6.14 2143.7 - 1.53E+06 - - - -1.9523 - 2.809 0.542 - 322.1 1 1 1 -0.0037 16 0 0 0 7.20E+05 1.82E+07 - - - 7.2318 0.9994 221125_WJC_METTL3_EV_vs_WT_F07.10956.10956.4 0.00227 Sep-78 R.LLEGEDAHLTQYKK.E "sp|Q04695|K1C17_HUMAN,tr|A0A3B3IS58|A0A3B3IS58_HUMAN,tr|F5GWP8|F5GWP8_HUMAN" 3 1643.8519 40.51 98725 10956 4 1643.850961 411.9702 "Keratin, type I cytoskeletal 17 OS=Homo sapiens OX=9606 GN=KRT17 PE=1 SV=2" 5.45 2143.8 - 4.96E+06 - - - -0.5627 - 2.158 0.317 - 48.1 1 2 0 -0.0009 14 0 0 0 6.61E+08 1.63E+07 - - - 2.2649 0.9996 221125_WJC_METTL3_EV_vs_WT_F07.10958.10958.4 0.00409 Dec-72 R.TLAHFRPIEDNEK.S "sp|Q99653|CHP1_HUMAN,tr|H0YLY7|H0YLY7_HUMAN,tr|F5GX29|F5GX29_HUMAN,tr|H0YKE7|H0YKE7_HUMAN,tr|H0YNG9|H0YNG9_HUMAN" 5 1568.7947 1.33 98727 10958 4 1568.794428 393.206 Calcineurin B homologous protein 1 OS=Homo sapiens OX=9606 GN=CHP1 PE=1 SV=3 5.41 2144 - 609020 - - - -0.1772 - 2.098 0.346 - 77.8 1 2 0 -0.0003 13 0 0 0 6.66E+06 5.02E+06 - - - 2.5122 0.9999 221125_WJC_METTL3_EV_vs_WT_F07.10960.10960.2 2.55E-05 Nov-36 K.EAGSEPAPEQESTEATPAE.- "sp|Q6UN15|FIP1_HUMAN,tr|H0Y8P7|H0Y8P7_HUMAN" 2 1928.8123 - 98729 10960 2 1928.811726 965.4134 Pre-mRNA 3'-end-processing factor FIP1 OS=Homo sapiens OX=9606 GN=FIP1L1 PE=1 SV=1 3.71 2144.3 - 485771 - - - -0.3111 - 1.672 0.584 - 147.9 1 2 0 -0.0006 19 0 0 0 - - - - - 4.618 1 221125_WJC_METTL3_EV_vs_WT_F07.10963.10963.3 8.71E-09 16/56 K.LSGWGNVSK[136.11]PSGTTK[136.11].S "sp|Q6Y7W6|GGYF2_HUMAN,tr|A0A7I2V3H7|A0A7I2V3H7_HUMAN,tr|I1E4Y6|I1E4Y6_HUMAN,tr|A0A7I2V516|A0A7I2V516_HUMAN,tr|A0A7I2V3H0|A0A7I2V3H0_HUMAN,tr|A0A7I2V361|A0A7I2V361_HUMAN" 6 1533.8122 2.73 98730 10963 3 1533.81053 512.278 GRB10-interacting GYF protein 2 OS=Homo sapiens OX=9606 GN=GIGYF2 PE=1 SV=1 10 2144.7 - 6.00E+06 - - - -1.0934 - 3.376 0.546 - 347.1 1 2 0 -0.0017 15 0 0 0 2.83E+08 1.04E+08 - - - 7.8017 1 221125_WJC_METTL3_EV_vs_WT_F07.10964.10964.3 1.66E-07 15/44 K.DGNLASTLGQHK[136.11].G "sp|Q9BZK7|TBL1R_HUMAN,sp|O60907|TBL1X_HUMAN,tr|A0A1B0GVH3|A0A1B0GVH3_HUMAN,tr|A0A804HJZ5|A0A804HJZ5_HUMAN,tr|A0A2R8YFW3|A0A2R8YFW3_HUMAN,tr|A0A0D9SF63|A0A0D9SF63_HUMAN" 6 1247.635 1.71 98731 10964 3 1247.633096 416.8856 F-box-like\WD repeat-containing protein TBL1XR1 OS=Homo sapiens OX=9606 GN=TBL1XR1 PE=1 SV=1 6.74 2144.7 - 3.88E+06 - - - -1.4972 - 2.725 0.576 - 479.9 1 2 0 -0.0019 12 0 0 0 8.65E+07 5.06E+07 - - - 7.74 0.9996 221125_WJC_METTL3_EV_vs_WT_F07.10965.10965.3 0.000314 17/52 R.DTALTIAADKGHYK.F "sp|O75179|ANR17_HUMAN,sp|Q8IWZ3|ANKH1_HUMAN,tr|E9PDP5|E9PDP5_HUMAN,tr|H0YM23|H0YM23_HUMAN,tr|H3BLS9|H3BLS9_HUMAN,tr|H0YLQ3|H0YLQ3_HUMAN,tr|H7C2F5|H7C2F5_HUMAN" 7 1502.7729 0.45 98732 10965 3 1502.773953 501.9316 Ankyrin repeat domain-containing protein 17 OS=Homo sapiens OX=9606 GN=ANKRD17 PE=1 SV=3 6.75 2144.9 - 1.38E+06 - - - 0.6954 - 3.648 0.307 - 471.6 1 2 1 0.001 14 0 0 0 8.67E+07 1.94E+08 - - - 5.4018 0.9996 221125_WJC_METTL3_EV_vs_WT_F07.10966.10966.3 0.00067 13/36 R.R[166.11]IEVNVELR[166.11]K[136.11].A "sp|P52292|IMA1_HUMAN,tr|J3QLL0|J3QLL0_HUMAN,tr|J3KS65|J3KS65_HUMAN,tr|A0A7I2V3Z3|A0A7I2V3Z3_HUMAN,tr|A0A7I2YQE1|A0A7I2YQE1_HUMAN,tr|A0A7I2V487|A0A7I2V487_HUMAN,tr|A0A7I2V351|A0A7I2V351_HUMAN" 7 1282.7716 1.21 98733 10966 3 1282.767936 428.5978 Importin subunit alpha-1 OS=Homo sapiens OX=9606 GN=KPNA2 PE=1 SV=1 8.75 2145 - 1.33E+06 - - - -2.8251 - 2.401 0.352 - 290.9 1 2 0 -0.0036 10 0 0 0 1.91E+07 1.57E+07 - - - 5.0214 0.9998 221125_WJC_METTL3_EV_vs_WT_F07.10970.10970.2 1.36E-08 28-Dec K.LSGWGNVSK[136.11]PSGTTK[136.11].S "sp|Q6Y7W6|GGYF2_HUMAN,tr|A0A7I2V3H7|A0A7I2V3H7_HUMAN,tr|I1E4Y6|I1E4Y6_HUMAN,tr|A0A7I2V516|A0A7I2V516_HUMAN,tr|A0A7I2V3H0|A0A7I2V3H0_HUMAN,tr|A0A7I2V361|A0A7I2V361_HUMAN" 6 1533.8122 4.03 98737 10970 2 1533.809129 767.9134 GRB10-interacting GYF protein 2 OS=Homo sapiens OX=9606 GN=GIGYF2 PE=1 SV=1 10 2145.5 - 306019 - - - -2.0068 - 2.361 0.574 - 324.6 1 2 0 -0.0031 15 0 0 0 1.66E+07 4.13E+06 - - - 5.3917 0.9997 221125_WJC_METTL3_EV_vs_WT_F07.10971.10971.2 0.000179 22-Aug K.LDIPTGTTPQR[166.11]K[136.11].S "sp|P52732|KIF11_HUMAN,tr|A0A7I2V3A9|A0A7I2V3A9_HUMAN" 2 1343.7528 6.11 98738 10971 2 1343.751569 672.8837 Kinesin-like protein KIF11 OS=Homo sapiens OX=9606 GN=KIF11 PE=1 SV=2 8.75 2145.6 - 292344 - - - -0.9042 - 1.634 0.487 - 190.2 1 2 0 -0.0012 12 0 0 0 2.86E+07 4.67E+06 - - - 3.9296 1 221125_WJC_METTL3_EV_vs_WT_F07.10974.10974.2 2.21E-07 14/32 R.LPPNTNDEVDEDPTGNK.A sp|Q15393|SF3B3_HUMAN 1 1853.8279 1.58 98740 10974 2 1853.827023 927.9212 Splicing factor 3B subunit 3 OS=Homo sapiens OX=9606 GN=SF3B3 PE=1 SV=4 3.77 2146.1 - 589764 - - - -0.4817 - 2.413 0.716 - 358.9 1 2 0 -0.0009 17 0 0 0 1.88E+07 1.19E+07 - - - 6.4948 0.9997 221125_WJC_METTL3_EV_vs_WT_F07.10976.10976.3 1.42E-06 13/52 K.LTLQHVNSNQC[160.03]LDK.A sp|Q10472|GALT1_HUMAN 1 1668.8254 1.45 98741 10976 3 1668.834256 557.2824 Polypeptide N-acetylgalactosaminyltransferase 1 OS=Homo sapiens OX=9606 GN=GALNT1 PE=1 SV=1 6.73 2146.3 - 2.06E+06 - - - 5.3343 - 2.636 0.583 - 262.2 1 2 0 0.0089 14 0 0 0 1.29E+08 8.84E+07 - - - 7.6133 0.9999 221125_WJC_METTL3_EV_vs_WT_F07.10977.10977.2 0.00679 22-Nov K.DGNLASTLGQHK.G "sp|Q9BZK7|TBL1R_HUMAN,sp|O60907|TBL1X_HUMAN,tr|A0A1B0GVH3|A0A1B0GVH3_HUMAN,tr|A0A804HJZ5|A0A804HJZ5_HUMAN,tr|A0A2R8YFW3|A0A2R8YFW3_HUMAN,tr|A0A0D9SF63|A0A0D9SF63_HUMAN" 6 1239.6208 2.11 98742 10977 2 1239.621247 620.8177 F-box-like\WD repeat-containing protein TBL1XR1 OS=Homo sapiens OX=9606 GN=TBL1XR1 PE=1 SV=1 6.74 2146.5 - 1.24E+06 - - - 0.3896 - 2.457 0.462 - 457.2 1 2 0 0.0005 12 0 0 0 1.77E+07 8.39E+06 - - - 4.8184 1 221125_WJC_METTL3_EV_vs_WT_F07.10979.10979.3 6.76E-07 15/44 K.DGNLASTLGQHK.G "sp|Q9BZK7|TBL1R_HUMAN,sp|O60907|TBL1X_HUMAN,tr|A0A1B0GVH3|A0A1B0GVH3_HUMAN,tr|A0A804HJZ5|A0A804HJZ5_HUMAN,tr|A0A2R8YFW3|A0A2R8YFW3_HUMAN,tr|A0A0D9SF63|A0A0D9SF63_HUMAN" 6 1239.6208 1.54 98744 10979 3 1239.619571 414.2142 F-box-like\WD repeat-containing protein TBL1XR1 OS=Homo sapiens OX=9606 GN=TBL1XR1 PE=1 SV=1 6.74 2146.5 - 7.08E+06 - - - -0.9624 - 2.898 0.524 - 401.2 1 2 0 -0.0012 12 0 0 0 8.70E+07 5.65E+07 - - - 7.3311 0.9315 221125_WJC_METTL3_EV_vs_WT_F07.10984.10984.4 0.0802 17/78 K.IDRLDGAHAPELTK.K sp|O76003|GLRX3_HUMAN 1 1534.8104 1.22 98749 10984 4 1534.809401 384.7099 Glutaredoxin-3 OS=Homo sapiens OX=9606 GN=GLRX3 PE=1 SV=2 5.38 2147.1 - 545730 - - - -0.6222 - 2.331 0.164 - 162.7 1 2 1 -0.001 14 0 0 0 2.32E+07 1.90E+07 - - - 0.9612 0.9994 221125_WJC_METTL3_EV_vs_WT_F07.10986.10986.3 0.00528 Oct-52 R.SIPLDEGEDEAQRR.R "sp|Q14204|DYHC1_HUMAN,tr|A0A7P0T8N2|A0A7P0T8N2_HUMAN,tr|A0A7P0T9C4|A0A7P0T9C4_HUMAN,tr|A0A7P0TBJ7|A0A7P0TBJ7_HUMAN,tr|A0A804HHY6|A0A804HHY6_HUMAN,tr|A0A7P0T9K2|A0A7P0T9K2_HUMAN,tr|A0A7P0TB64|A0A7P0TB64_HUMAN,tr|A0A2R8Y706|A0A2R8Y706_HUMAN,tr|A0A7P0T916|A0A7P0T916_HUMAN,tr|A0A7P0TB75|A0A7P0TB75_HUMAN,tr|A0A7P0T8W5|A0A7P0T8W5_HUMAN,tr|A0A7P0TAF3|A0A7P0TAF3_HUMAN,tr|A0A7P0T9F1|A0A7P0T9F1_HUMAN,tr|A0A7P0TAW9|A0A7P0TAW9_HUMAN,tr|A0A2R8YGC7|A0A2R8YGC7_HUMAN,tr|A0A7P0TA13|A0A7P0TA13_HUMAN,tr|A0A7P0TAV5|A0A7P0TAV5_HUMAN,tr|A0A7P0T7V5|A0A7P0T7V5_HUMAN,tr|A0A7P0T9R4|A0A7P0T9R4_HUMAN,tr|A0A2R8Y5T0|A0A2R8Y5T0_HUMAN,tr|A0A7P0T990|A0A7P0T990_HUMAN,tr|A0A7P0T942|A0A7P0T942_HUMAN,tr|A0A2R8YFZ7|A0A2R8YFZ7_HUMAN,tr|A0A7P0T825|A0A7P0T825_HUMAN,tr|A0A2R8Y6H2|A0A2R8Y6H2_HUMAN,tr|A0A7P0TAM4|A0A7P0TAM4_HUMAN" 26 1613.7645 1.46 98751 10986 3 1613.764518 538.9288 Cytoplasmic dynein 1 heavy chain 1 OS=Homo sapiens OX=9606 GN=DYNC1H1 PE=1 SV=5 4.18 2147.4 - 409371 - - - -0.0062 - 1.78 0.326 - 143.7 1 2 0 0 14 0 0 0 3.35E+07 2.30E+07 - - - 3.7069 1 221125_WJC_METTL3_EV_vs_WT_F07.10991.10991.3 7.69E-06 14/52 K.LTLQHVNSNQC[160.03]LDK[136.11].A sp|Q10472|GALT1_HUMAN 1 1676.8396 1.44 98754 10991 3 1676.83787 559.9538 Polypeptide N-acetylgalactosaminyltransferase 1 OS=Homo sapiens OX=9606 GN=GALNT1 PE=1 SV=1 6.73 2147.9 - 3.21E+06 - - - -1.0043 - 2.822 0.485 - 277.8 1 2 0 -0.0017 14 0 0 0 1.28E+08 8.90E+07 - - - 6.7039 1 221125_WJC_METTL3_EV_vs_WT_F07.10997.10997.2 1.36E-11 19/26 R.LLEGEDAHLTQYKK.E "sp|Q04695|K1C17_HUMAN,tr|A0A3B3IS58|A0A3B3IS58_HUMAN,tr|F5GWP8|F5GWP8_HUMAN" 3 1643.8519 999 98760 10997 2 1643.850902 822.9332 "Keratin, type I cytoskeletal 17 OS=Homo sapiens OX=9606 GN=KRT17 PE=1 SV=2" 5.45 2148.5 - 862459 - - - -0.5986 - 3.589 0.657 - 984.7 1 2 0 -0.001 14 0 0 0 2.04E+07 0.00E+00 - - - 7.1001 1 221125_WJC_METTL3_EV_vs_WT_F07.10998.10998.2 2.65E-07 18/22 L.EGEDAHLTQYKK.E "sp|Q04695|K1C17_HUMAN,tr|A0A3B3IS58|A0A3B3IS58_HUMAN,tr|F5GWP8|F5GWP8_HUMAN" 3 1417.6838 999 98761 10998 2 1417.681866 709.8492 "Keratin, type I cytoskeletal 17 OS=Homo sapiens OX=9606 GN=KRT17 PE=1 SV=2" 5.45 2148.6 - 781880 - - - -1.3346 - 3.274 0.601 - 841.3 1 1 0 -0.0019 12 0 0 0 1.39E+07 0.00E+00 - - - 6.6 0.8355 221125_WJC_METTL3_EV_vs_WT_F07.10999.10999.3 0.0805 Sep-40 E.GEDAHLTQYKK.E "sp|Q04695|K1C17_HUMAN,tr|A0A3B3IS58|A0A3B3IS58_HUMAN,tr|F5GWP8|F5GWP8_HUMAN" 3 1288.6412 1.46 98762 10999 3 1288.641399 430.5543 "Keratin, type I cytoskeletal 17 OS=Homo sapiens OX=9606 GN=KRT17 PE=1 SV=2" 6.75 2148.7 - 333170 - - - 0.1816 - 1.463 0.292 - 78.5 1 1 0 0.0002 11 0 0 0 2.01E+06 1.38E+06 - - - 2.8763 0.9688 221125_WJC_METTL3_EV_vs_WT_F07.11001.11001.2 7.21E-08 13/28 R.SDSPVPTAPTSGGPK[136.11].P "sp|Q86U44|MTA70_HUMAN,tr|B4E349|B4E349_HUMAN,tr|F5H6D8|F5H6D8_HUMAN,tr|B4DTN4|B4DTN4_HUMAN" 4 1404.6976 0.03 98763 11001 2 1404.694326 703.3561 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 5.55 2149 - 760383 - - - -2.3478 - 2.348 0.405 - 484.3 1 1 0 -0.0033 15 0 0 0 5.51E+05 1.80E+07 - - - 4.1298 1 221125_WJC_METTL3_EV_vs_WT_F07.11006.11006.3 9.93E-06 Dec-52 R.SIPLDEGEDEAQR[166.11]R[166.11].R "sp|Q14204|DYHC1_HUMAN,tr|A0A7P0T8N2|A0A7P0T8N2_HUMAN,tr|A0A7P0T9C4|A0A7P0T9C4_HUMAN,tr|A0A7P0TBJ7|A0A7P0TBJ7_HUMAN,tr|A0A804HHY6|A0A804HHY6_HUMAN,tr|A0A7P0T9K2|A0A7P0T9K2_HUMAN,tr|A0A7P0TB64|A0A7P0TB64_HUMAN,tr|A0A2R8Y706|A0A2R8Y706_HUMAN,tr|A0A7P0T916|A0A7P0T916_HUMAN,tr|A0A7P0TB75|A0A7P0TB75_HUMAN,tr|A0A7P0T8W5|A0A7P0T8W5_HUMAN,tr|A0A7P0TAF3|A0A7P0TAF3_HUMAN,tr|A0A7P0T9F1|A0A7P0T9F1_HUMAN,tr|A0A7P0TAW9|A0A7P0TAW9_HUMAN,tr|A0A2R8YGC7|A0A2R8YGC7_HUMAN,tr|A0A7P0TA13|A0A7P0TA13_HUMAN,tr|A0A7P0TAV5|A0A7P0TAV5_HUMAN,tr|A0A7P0T7V5|A0A7P0T7V5_HUMAN,tr|A0A7P0T9R4|A0A7P0T9R4_HUMAN,tr|A0A2R8Y5T0|A0A2R8Y5T0_HUMAN,tr|A0A7P0T990|A0A7P0T990_HUMAN,tr|A0A7P0T942|A0A7P0T942_HUMAN,tr|A0A2R8YFZ7|A0A2R8YFZ7_HUMAN,tr|A0A7P0T825|A0A7P0T825_HUMAN,tr|A0A2R8Y6H2|A0A2R8Y6H2_HUMAN,tr|A0A7P0TAM4|A0A7P0TAM4_HUMAN" 26 1633.7811 1.53 98767 11006 3 1633.779647 545.601 Cytoplasmic dynein 1 heavy chain 1 OS=Homo sapiens OX=9606 GN=DYNC1H1 PE=1 SV=5 4.18 2149.4 - 1.12E+06 - - - -0.8698 - 2.034 0.494 - 190 1 2 0 -0.0014 14 0 0 0 3.51E+07 2.30E+07 - - - 5.9341 0.9998 221125_WJC_METTL3_EV_vs_WT_F07.11010.11010.2 2.00E-05 26-Aug K.LTLQHVNSNQC[160.03]LDK[136.11].A sp|Q10472|GALT1_HUMAN 1 1676.8396 2.13 98771 11010 2 1676.837987 839.4271 Polypeptide N-acetylgalactosaminyltransferase 1 OS=Homo sapiens OX=9606 GN=GALNT1 PE=1 SV=1 6.73 2150 - 327469 - - - -0.9345 - 1.86 0.544 - 234.6 1 2 0 -0.0016 14 0 0 0 5.30E+06 2.49E+06 - - - 4.6158 0.9012 221125_WJC_METTL3_EV_vs_WT_F07.11016.11016.3 0.0867 Oct-52 R.SSTTSMTSVPK[136.11]PLK[136.11].F "sp|Q13200|PSMD2_HUMAN,tr|C9JPC0|C9JPC0_HUMAN,tr|H7C2Q3|H7C2Q3_HUMAN" 3 1478.7985 0.28 98775 11016 3 1478.79878 493.9401 26S proteasome non-ATPase regulatory subunit 2 OS=Homo sapiens OX=9606 GN=PSMD2 PE=1 SV=3 10 2150.5 - 3.98E+06 - - - 0.1691 - 1.475 0.079 - 67.5 1 2 0 0.0003 14 0 0 0 1.27E+07 4.54E+07 - - - 0.4536 0.9136 221125_WJC_METTL3_EV_vs_WT_F07.11020.11020.2 0.116 24-Aug R.VRNESSFSASLGR.A sp|Q5JSZ5|PRC2B_HUMAN 1 1408.7059 5.91 98779 11020 2 1408.702576 705.3602 Protein PRRC2B OS=Homo sapiens OX=9606 GN=PRRC2B PE=1 SV=2 9.57 2151.1 - 663780 - - - -2.3532 - 1.228 0.258 - 48.5 1 2 1 -0.0033 13 0 0 0 1.43E+07 2.41E+06 - - - 1.4727 0.9999 221125_WJC_METTL3_EV_vs_WT_F07.11021.11021.4 0.000108 13/90 K.NLPLADQGSSHHITVK.L sp|P15924|DESP_HUMAN 1 1715.8955 58.29 98780 11021 4 1715.894643 429.9811 Desmoplakin OS=Homo sapiens OX=9606 GN=DSP PE=1 SV=3 6.92 2151.2 - 610407 - - - -0.489 - 2.377 0.397 - 86.5 1 2 0 -0.0008 16 0 0 0 1.43E+07 2.45E+05 - - - 2.9863 1 221125_WJC_METTL3_EV_vs_WT_F07.11023.11023.3 0.000173 13/60 R.ASGNYATVISHNPETK[136.11].K "sp|P62917|RL8_HUMAN,tr|G3V1A1|G3V1A1_HUMAN,tr|E9PKZ0|E9PKZ0_HUMAN" 3 1695.8308 1.57 98781 11023 3 1695.830101 566.2842 60S ribosomal protein L8 OS=Homo sapiens OX=9606 GN=RPL8 PE=1 SV=2 6.79 2151.4 - 2.21E+06 - - - -0.3904 - 2.894 0.525 - 201.4 1 2 0 -0.0007 16 0 0 0 8.22E+07 5.22E+07 - - - 7.1196 1 221125_WJC_METTL3_EV_vs_WT_F07.11028.11028.3 2.96E-11 18/48 K.LR[166.11]ENVFQEHQTLK[136.11].E sp|Q14247|SRC8_HUMAN 1 1658.8859 1.02 98785 11028 3 1658.882127 553.9693 Src substrate cortactin OS=Homo sapiens OX=9606 GN=CTTN PE=1 SV=2 6.76 2151.9 - 969482 - - - -2.2889 - 3.418 0.594 - 354.3 1 2 1 -0.0038 13 0 0 0 1.77E+07 1.73E+07 - - - 8.4938 1 221125_WJC_METTL3_EV_vs_WT_F07.11029.11029.2 6.15E-10 15/38 K.MEEESGAPGVPSGNGAPGPK.G "sp|P52272|HNRPM_HUMAN,tr|M0R019|M0R019_HUMAN,tr|M0R0Y6|M0R0Y6_HUMAN,tr|M0R0N3|M0R0N3_HUMAN,tr|A0A087X0X3|A0A087X0X3_HUMAN,tr|M0QYQ7|M0QYQ7_HUMAN,tr|M0R2T0|M0R2T0_HUMAN" 7 1866.8418 2.2 98786 11029 2 1866.844135 934.4282 Heterogeneous nuclear ribonucleoprotein M OS=Homo sapiens OX=9606 GN=HNRNPM PE=1 SV=3 4.25 2152 - 515548 - - - 1.2551 - 2.893 0.673 - 400.1 1 2 0 0.0023 20 0 0 0 1.61E+08 7.33E+07 - - - 6.6227 0.9994 221125_WJC_METTL3_EV_vs_WT_F07.11032.11032.3 0.0999 Nov-60 R.ASGNYATVISHNPETK.K "sp|P62917|RL8_HUMAN,tr|G3V1A1|G3V1A1_HUMAN,tr|E9PKZ0|E9PKZ0_HUMAN" 3 1687.8166 1.14 98787 11032 3 1687.816754 563.6128 60S ribosomal protein L8 OS=Homo sapiens OX=9606 GN=RPL8 PE=1 SV=2 6.79 2152.4 - 4.71E+06 - - - 0.1132 - 1.936 0.312 - 115.5 1 2 0 0.0002 16 0 0 0 8.39E+07 7.33E+07 - - - 3.7135 0.9997 221125_WJC_METTL3_EV_vs_WT_F07.11034.11034.3 0.000539 14/40 K.HGGVIHIYVDK[136.11].N "sp|Q14498|RBM39_HUMAN,tr|H0Y4X3|H0Y4X3_HUMAN" 2 1244.6757 1.42 98789 11034 3 1244.671082 415.8992 RNA-binding protein 39 OS=Homo sapiens OX=9606 GN=RBM39 PE=1 SV=2 6.92 2152.6 - 1.17E+06 - - - -3.7158 - 2.448 0.445 - 248.9 1 2 0 -0.0046 11 0 0 0 1.99E+07 1.40E+07 - - - 6.0433 1 221125_WJC_METTL3_EV_vs_WT_F07.11039.11039.3 2.00E-07 16/76 K.MEEESGAPGVPSGNGAPGPK.G "sp|P52272|HNRPM_HUMAN,tr|M0R019|M0R019_HUMAN,tr|M0R0Y6|M0R0Y6_HUMAN,tr|M0R0N3|M0R0N3_HUMAN,tr|A0A087X0X3|A0A087X0X3_HUMAN,tr|M0QYQ7|M0QYQ7_HUMAN,tr|M0R2T0|M0R2T0_HUMAN" 7 1866.8418 3.05 98792 11039 3 1866.840109 623.2879 Heterogeneous nuclear ribonucleoprotein M OS=Homo sapiens OX=9606 GN=HNRNPM PE=1 SV=3 4.25 2153.2 - 1.33E+06 - - - -0.9015 - 2.809 0.581 - 260.1 1 2 0 -0.0017 20 0 0 0 1.87E+08 6.11E+07 - - - 7.5228 0.9977 221125_WJC_METTL3_EV_vs_WT_F07.11040.11040.3 7.28E-07 14/44 L.EGEDAHLTQYKK.E "sp|Q04695|K1C17_HUMAN,tr|A0A3B3IS58|A0A3B3IS58_HUMAN,tr|F5GWP8|F5GWP8_HUMAN" 3 1417.6838 147.84 98793 11040 3 1417.681694 473.5685 "Keratin, type I cytoskeletal 17 OS=Homo sapiens OX=9606 GN=KRT17 PE=1 SV=2" 5.45 2153.4 - 630381 - - - -1.4559 - 2.676 0.541 - 227.8 1 1 0 -0.0021 12 0 0 0 2.07E+07 1.40E+05 - - - 7.2994 0.9998 221125_WJC_METTL3_EV_vs_WT_F07.11043.11043.3 1.51E-05 13/52 R.GK[136.11]ATISNDGATILK[136.11].L "sp|Q99832|TCPH_HUMAN,tr|F8WAM2|F8WAM2_HUMAN" 2 1403.7955 0.001 98796 11043 3 1403.795165 468.9391 T-complex protein 1 subunit eta OS=Homo sapiens OX=9606 GN=CCT7 PE=1 SV=2 8.59 2153.6 - 1.43E+06 - - - -0.2344 - 2.396 0.479 - 217.4 1 2 1 -0.0003 14 0 0 0 0.00E+00 1.92E+07 - - - 6.2024 0.9884 221125_WJC_METTL3_EV_vs_WT_F07.11044.11044.3 0.0124 Sep-44 K.GISVHISNAEPK[136.11].H "sp|Q13148|TADBP_HUMAN,tr|A0A087WX67|A0A087WX67_HUMAN,tr|A0A087WX29|A0A087WX29_HUMAN,tr|G3V162|G3V162_HUMAN,tr|A0A087WV68|A0A087WV68_HUMAN,tr|A0A087WXV3|A0A087WXV3_HUMAN,tr|A0A087WYY0|A0A087WYY0_HUMAN,tr|A0A087WTZ4|A0A087WTZ4_HUMAN,tr|A0A087WW61|A0A087WW61_HUMAN,tr|A0A087WYE7|A0A087WYE7_HUMAN,tr|B1AKP7|B1AKP7_HUMAN,tr|K7EL26|K7EL26_HUMAN,tr|A0A087WZC9|A0A087WZC9_HUMAN,tr|A0A087WXQ5|A0A087WXQ5_HUMAN,tr|A0A087X260|A0A087X260_HUMAN" 15 1258.6761 1.41 98797 11044 3 1258.675097 420.566 TAR DNA-binding protein 43 OS=Homo sapiens OX=9606 GN=TARDBP PE=1 SV=1 6.75 2153.7 - 859597 - - - -0.7969 - 1.621 0.165 - 76.8 1 2 0 -0.001 12 0 0 0 7.13E+07 5.06E+07 - - - 1.7182 1 221125_WJC_METTL3_EV_vs_WT_F07.11045.11045.2 3.01E-12 18/38 K.MEEESGAPGVPSGNGAPGPK[136.11].G "sp|P52272|HNRPM_HUMAN,tr|M0R019|M0R019_HUMAN,tr|M0R0Y6|M0R0Y6_HUMAN,tr|M0R0N3|M0R0N3_HUMAN,tr|A0A087X0X3|A0A087X0X3_HUMAN,tr|M0QYQ7|M0QYQ7_HUMAN,tr|M0R2T0|M0R2T0_HUMAN" 7 1874.856 2.2 98798 11045 2 1874.851961 938.4353 Heterogeneous nuclear ribonucleoprotein M OS=Homo sapiens OX=9606 GN=HNRNPM PE=1 SV=3 4.25 2153.9 - 509400 - - - -2.15 - 3.026 0.788 - 567.9 1 2 0 -0.004 20 0 0 0 1.61E+08 7.33E+07 - - - 7.5821 0.9992 221125_WJC_METTL3_EV_vs_WT_F07.11049.11049.3 0.0799 Sep-44 K.GISVHISNAEPK.H "sp|Q13148|TADBP_HUMAN,tr|A0A087WX67|A0A087WX67_HUMAN,tr|A0A087WX29|A0A087WX29_HUMAN,tr|G3V162|G3V162_HUMAN,tr|A0A087WV68|A0A087WV68_HUMAN,tr|A0A087WXV3|A0A087WXV3_HUMAN,tr|A0A087WYY0|A0A087WYY0_HUMAN,tr|A0A087WTZ4|A0A087WTZ4_HUMAN,tr|A0A087WW61|A0A087WW61_HUMAN,tr|A0A087WYE7|A0A087WYE7_HUMAN,tr|B1AKP7|B1AKP7_HUMAN,tr|K7EL26|K7EL26_HUMAN,tr|A0A087WZC9|A0A087WZC9_HUMAN,tr|A0A087WXQ5|A0A087WXQ5_HUMAN,tr|A0A087X260|A0A087X260_HUMAN" 15 1250.6619 1.41 98800 11049 3 1250.660792 417.8946 TAR DNA-binding protein 43 OS=Homo sapiens OX=9606 GN=TARDBP PE=1 SV=1 6.75 2154.4 - 2.21E+06 - - - -0.8859 - 1.435 0.35 - 62.9 1 2 0 -0.0011 12 0 0 0 7.15E+07 5.07E+07 - - - 3.4429 1 221125_WJC_METTL3_EV_vs_WT_F07.11051.11051.3 2.80E-07 15/76 K.MEEESGAPGVPSGNGAPGPK[136.11].G "sp|P52272|HNRPM_HUMAN,tr|M0R019|M0R019_HUMAN,tr|M0R0Y6|M0R0Y6_HUMAN,tr|M0R0N3|M0R0N3_HUMAN,tr|A0A087X0X3|A0A087X0X3_HUMAN,tr|M0QYQ7|M0QYQ7_HUMAN,tr|M0R2T0|M0R2T0_HUMAN" 7 1874.856 3.05 98802 11051 3 1874.857244 625.9593 Heterogeneous nuclear ribonucleoprotein M OS=Homo sapiens OX=9606 GN=HNRNPM PE=1 SV=3 4.25 2154.6 - 1.25E+06 - - - 0.6678 - 2.308 0.603 - 248.6 1 2 0 0.0013 20 0 0 0 1.87E+08 6.11E+07 - - - 7.2916 0.9999 221125_WJC_METTL3_EV_vs_WT_F07.11056.11056.2 0.000111 Aug-36 R.KPVTVSPTTPTSPTEGEAS.- "sp|Q9Y6G9|DC1L1_HUMAN,tr|E9PHI6|E9PHI6_HUMAN" 2 1884.9317 0.72 98807 11056 2 1884.930258 943.4731 Cytoplasmic dynein 1 light intermediate chain 1 OS=Homo sapiens OX=9606 GN=DYNC1LI1 PE=1 SV=3 4.53 2155.3 - 278276 - - - -0.7401 - 1.956 0.558 - 119.3 1 2 0 -0.0014 19 0 0 0 6.97E+06 9.73E+06 - - - 4.8114 1 221125_WJC_METTL3_EV_vs_WT_F07.11059.11059.3 6.91E-07 19/60 R.AFQNTATAC[160.03]APVSHYR[166.11].A sp|Q9H814|PHAX_HUMAN 1 1802.8398 0.73 98808 11059 3 1802.839519 601.9539 Phosphorylated adapter RNA export protein OS=Homo sapiens OX=9606 GN=PHAX PE=1 SV=1 8.27 2155.7 - 797652 - - - -0.1403 - 3.21 0.66 - 465.6 1 2 0 -0.0003 16 0 0 0 7.25E+06 9.88E+06 - - - 8.8908 1 221125_WJC_METTL3_EV_vs_WT_F07.11060.11060.2 2.87E-08 13/36 R.K[136.11]PVTVSPTTPTSPTEGEAS.- "sp|Q9Y6G9|DC1L1_HUMAN,tr|E9PHI6|E9PHI6_HUMAN" 2 1892.9459 0.71 98809 11060 2 1892.945299 947.4802 Cytoplasmic dynein 1 light intermediate chain 1 OS=Homo sapiens OX=9606 GN=DYNC1LI1 PE=1 SV=3 4.53 2155.8 - 406384 - - - -0.2927 - 3.148 0.692 - 382.1 1 2 0 -0.0006 19 0 0 0 6.97E+06 9.85E+06 - - - 6.9713 0.9997 221125_WJC_METTL3_EV_vs_WT_F07.11062.11062.3 0.0302 Nov-52 K.YDEELEGER[166.11]PHSFR[166.11].L sp|O43290|SNUT1_HUMAN 1 1782.8076 2.57 98811 11062 3 1782.803977 595.2765 U4\U6.U5 tri-snRNP-associated protein 1 OS=Homo sapiens OX=9606 GN=SART1 PE=1 SV=1 4.57 2156.1 - 336946 - - - -2.0417 - 2.221 0.356 - 137.3 1 2 0 -0.0036 14 0 0 0 2.39E+07 9.31E+06 - - - 4.6286 0.9806 221125_WJC_METTL3_EV_vs_WT_F07.11065.11065.3 0.338 Nov-52 H.K[136.11]LLYNR[166.11]PGTVSSLK[136.11].K "sp|P35659|DEK_HUMAN,tr|H0Y8X0|H0Y8X0_HUMAN,tr|H0Y993|H0Y993_HUMAN,tr|A0A494C028|A0A494C028_HUMAN,tr|D6RDA2|D6RDA2_HUMAN,tr|B4DFG0|B4DFG0_HUMAN" 6 1600.9511 0.62 98812 11065 3 1600.950371 534.6576 Protein DEK OS=Homo sapiens OX=9606 GN=DEK PE=1 SV=1 10.29 2156.5 - 912361 - - - -0.4535 - 2 0.38 - 130.7 1 1 0 -0.0007 14 0 0 0 1.22E+07 1.95E+07 - - - 4.6185 0.9999 221125_WJC_METTL3_EV_vs_WT_F07.11066.11066.3 0.000719 Oct-52 K.YDEELEGERPHSFR.L sp|O43290|SNUT1_HUMAN 1 1762.7911 2.57 98813 11066 3 1762.790588 588.6043 U4\U6.U5 tri-snRNP-associated protein 1 OS=Homo sapiens OX=9606 GN=SART1 PE=1 SV=1 4.57 2156.6 - 509317 - - - -0.2774 - 2.144 0.478 - 112.1 1 2 0 -0.0005 14 0 0 0 2.39E+07 9.31E+06 - - - 5.8959 1 221125_WJC_METTL3_EV_vs_WT_F07.11068.11068.3 5.87E-07 Nov-40 R.HSEAFEALQQK[136.11].S sp|Q07065|CKAP4_HUMAN 1 1294.6397 1.8 98815 11068 3 1294.638585 432.5538 Cytoskeleton-associated protein 4 OS=Homo sapiens OX=9606 GN=CKAP4 PE=1 SV=2 5.4 2156.9 - 313800 - - - -0.8728 - 2.363 0.55 - 167 1 2 0 -0.0011 11 0 0 0 6.31E+07 3.50E+07 - - - 7.1146 0.9908 221125_WJC_METTL3_EV_vs_WT_F07.11070.11070.3 0.00744 Sep-36 R.HKPLLIDMNK.V "sp|Q15149|PLEC_HUMAN,tr|E9PMV1|E9PMV1_HUMAN,tr|E9PKG0|E9PKG0_HUMAN,tr|H0YDN1|H0YDN1_HUMAN" 4 1207.6747 3.19 98817 11070 3 1207.672424 403.5655 Plectin OS=Homo sapiens OX=9606 GN=PLEC PE=1 SV=3 8.6 2157.1 - 261977 - - - -1.8962 - 1.517 0.217 - 91.2 1 2 0 -0.0023 10 0 0 0 1.01E+07 3.16E+06 - - - 2.1757 1 221125_WJC_METTL3_EV_vs_WT_F07.11075.11075.3 3.10E-06 15/56 K.IGSC[160.03]TQQDVELHVQK[136.11].L "sp|P14868|SYDC_HUMAN,tr|C9JQM9|C9JQM9_HUMAN,tr|C9J7S3|C9J7S3_HUMAN,tr|H7C278|H7C278_HUMAN,tr|C9JLC1|C9JLC1_HUMAN" 5 1748.8607 1.36 98820 11075 3 1748.861399 583.9608 "Aspartate--tRNA ligase, cytoplasmic OS=Homo sapiens OX=9606 GN=DARS1 PE=1 SV=2" 5.32 2157.8 - 1.75E+06 - - - 0.4088 - 2.631 0.47 - 324.6 1 2 0 0.0007 15 0 0 0 5.06E+07 3.70E+07 - - - 6.304 1 221125_WJC_METTL3_EV_vs_WT_F07.11076.11076.3 9.85E-08 Nov-56 K.IGSC[160.03]TQQDVELHVQK.L "sp|P14868|SYDC_HUMAN,tr|C9JQM9|C9JQM9_HUMAN,tr|C9J7S3|C9J7S3_HUMAN,tr|H7C278|H7C278_HUMAN,tr|C9JLC1|C9JLC1_HUMAN" 5 1740.8465 1.41 98821 11076 3 1740.844262 581.2894 "Aspartate--tRNA ligase, cytoplasmic OS=Homo sapiens OX=9606 GN=DARS1 PE=1 SV=2" 5.32 2157.9 - 1.90E+06 - - - -1.2764 - 2.77 0.514 - 187.9 1 2 0 -0.0022 15 0 0 0 5.71E+07 4.06E+07 - - - 6.9285 1 221125_WJC_METTL3_EV_vs_WT_F07.11078.11078.3 0.000112 15/40 R.HSEAFEALQQK.S sp|Q07065|CKAP4_HUMAN 1 1286.6255 1.65 98823 11078 3 1286.625378 429.8824 Cytoskeleton-associated protein 4 OS=Homo sapiens OX=9606 GN=CKAP4 PE=1 SV=2 5.4 2158 - 1.65E+06 - - - -0.1065 - 2.844 0.523 - 294.5 1 2 0 -0.0001 11 0 0 0 6.65E+07 4.03E+07 - - - 7.3402 0.9977 221125_WJC_METTL3_EV_vs_WT_F07.11079.11079.3 0.0086 Oct-44 R.QMFHDALREPGK.A sp|Q8IU81|I2BP1_HUMAN 1 1427.698 1.57 98824 11079 3 1427.699183 476.9066 Interferon regulatory factor 2-binding protein 1 OS=Homo sapiens OX=9606 GN=IRF2BP1 PE=1 SV=1 6.75 2158.1 - 1.08E+06 - - - 0.851 - 1.868 0.322 - 145.1 1 2 1 0.0012 12 0 0 0 1.85E+07 1.18E+07 - - - 3.8617 0.9939 221125_WJC_METTL3_EV_vs_WT_F07.11082.11082.3 0.0239 Dec-44 N.PSDSAVHSPFTK.R "sp|Q14157|UBP2L_HUMAN,tr|F8W726|F8W726_HUMAN" 2 1271.6146 1.99 98827 11082 3 1271.615152 424.8788 Ubiquitin-associated protein 2-like OS=Homo sapiens OX=9606 GN=UBAP2L PE=1 SV=2 7.17 2158.4 - 444595 - - - 0.4215 - 2.672 0.401 - 123.5 1 1 0 0.0005 12 0 0 0 6.04E+06 3.03E+06 - - - 5.7349 0.856 221125_WJC_METTL3_EV_vs_WT_F07.11084.11084.3 0.000136 Nov-44 N.PSDSAVHSPFTK[136.11].R "sp|Q14157|UBP2L_HUMAN,tr|F8W726|F8W726_HUMAN" 2 1279.6288 2.07 98829 11084 3 1279.621965 427.5502 Ubiquitin-associated protein 2-like OS=Homo sapiens OX=9606 GN=UBAP2L PE=1 SV=2 7.17 2158.7 - 271124 - - - -5.3539 - 2.069 0.439 - 130.6 1 1 0 -0.0069 12 0 0 0 9.07E+06 4.37E+06 - - - 5.4478 1 221125_WJC_METTL3_EV_vs_WT_F07.11086.11086.3 2.79E-05 Nov-60 K.ATAGDTHLGGEDFDNR[166.11].L "sp|P48741|HSP77_HUMAN,sp|P0DMV8|HS71A_HUMAN,sp|P34931|HS71L_HUMAN,sp|P0DMV9|HS71B_HUMAN,sp|P17066|HSP76_HUMAN,tr|Q53FA3|Q53FA3_HUMAN,tr|V9GZ37|V9GZ37_HUMAN,tr|A0A0G2JIW1|A0A0G2JIW1_HUMAN" 8 1684.7317 0.001 98830 11086 3 1684.732263 562.5845 Putative heat shock 70 kDa protein 7 OS=Homo sapiens OX=9606 GN=HSPA7 PE=5 SV=2 4.22 2158.9 - 926917 - - - 0.3573 - 2.197 0.52 - 165.8 1 2 0 0.0006 16 0 0 0 0.00E+00 3.93E+07 - - - 6.3569 0.9999 221125_WJC_METTL3_EV_vs_WT_F07.11090.11090.2 5.13E-07 24-Dec K.NPSDSAVHSPFTK[136.11].R "sp|Q14157|UBP2L_HUMAN,tr|F8W726|F8W726_HUMAN" 2 1393.6717 2.61 98833 11090 2 1393.671806 697.8431 Ubiquitin-associated protein 2-like OS=Homo sapiens OX=9606 GN=UBAP2L PE=1 SV=2 6.74 2159.2 - 2.10E+06 - - - 0.0452 - 2.199 0.595 - 411.7 1 2 0 0.0001 13 0 0 0 2.67E+08 1.02E+08 - - - 5.4581 1 221125_WJC_METTL3_EV_vs_WT_F07.11091.11091.3 1.41E-05 Dec-44 K.EENNHLQEELER.L "sp|Q15643|TRIPB_HUMAN,tr|H0YJ97|H0YJ97_HUMAN" 2 1538.6961 0.53 98834 11091 3 1538.695744 513.906 Thyroid receptor-interacting protein 11 OS=Homo sapiens OX=9606 GN=TRIP11 PE=1 SV=3 4.32 2159.3 - 1.22E+06 - - - -0.2405 - 2.233 0.51 - 269.4 1 2 0 -0.0004 12 0 0 0 5.39E+07 1.01E+08 - - - 6.4526 0.9999 221125_WJC_METTL3_EV_vs_WT_F07.11093.11093.3 0.00024 Aug-44 K.TWNHFSDNEAER[166.11].V sp|Q99543|DNJC2_HUMAN 1 1514.6414 0.07 98836 11093 3 1514.641699 505.8877 DnaJ homolog subfamily C member 2 OS=Homo sapiens OX=9606 GN=DNAJC2 PE=1 SV=4 4.65 2159.4 - 960292 - - - 0.204 - 1.843 0.426 - 97.7 1 2 0 0.0003 12 0 0 0 2.29E+06 3.19E+07 - - - 4.9841 1 221125_WJC_METTL3_EV_vs_WT_F07.11094.11094.3 2.49E-09 21/72 K.VVQVSAGDSHTAALTDDGR[166.11].V "sp|P18754|RCC1_HUMAN,tr|C9JQZ4|C9JQZ4_HUMAN,tr|C9J3R0|C9J3R0_HUMAN,tr|C9JMJ4|C9JMJ4_HUMAN,tr|C9JW69|C9JW69_HUMAN,tr|C9JRH2|C9JRH2_HUMAN" 6 1907.9213 0.71 98837 11094 3 1907.923067 636.981 Regulator of chromosome condensation OS=Homo sapiens OX=9606 GN=RCC1 PE=1 SV=1 4.41 2159.6 - 646063 - - - 0.9508 - 3.853 0.424 - 570.5 1 2 0 0.0018 19 0 0 0 4.97E+07 7.05E+07 - - - 6.5805 0.9999 221125_WJC_METTL3_EV_vs_WT_F07.11097.11097.3 0.00032 Oct-44 K.TWNHFSDNEAER.V sp|Q99543|DNJC2_HUMAN 1 1504.6331 0.3 98840 11097 3 1504.63589 502.5516 DnaJ homolog subfamily C member 2 OS=Homo sapiens OX=9606 GN=DNAJC2 PE=1 SV=4 4.65 2159.9 - 428632 - - - 1.841 - 2.169 0.479 - 124.7 1 2 0 0.0028 12 0 0 0 9.86E+06 3.28E+07 - - - 6.0258 0.9998 221125_WJC_METTL3_EV_vs_WT_F07.11098.11098.3 2.31E-06 Nov-60 R.AFQNTATAC[160.03]APVSHYR.A sp|Q9H814|PHAX_HUMAN 1 1792.8315 0.72 98841 11098 3 1792.823439 598.6178 Phosphorylated adapter RNA export protein OS=Homo sapiens OX=9606 GN=PHAX PE=1 SV=1 8.27 2160.1 - 372413 - - - -4.4974 - 2.279 0.572 - 129.5 1 2 0 -0.0081 16 0 0 0 7.25E+06 1.00E+07 - - - 7.0286 1 221125_WJC_METTL3_EV_vs_WT_F07.11099.11099.3 0.000183 16/48 K.HLQHLAEVSAEVR[166.11].E "sp|O95229|ZWINT_HUMAN,tr|A6NH27|A6NH27_HUMAN" 2 1497.7927 4.75 98842 11099 3 1497.791942 500.2715 ZW10 interactor OS=Homo sapiens OX=9606 GN=ZWINT PE=1 SV=2 6 2160.2 - 304582 - - - -0.5361 - 3.666 0.417 - 486.9 1 2 0 -0.0008 13 0 0 0 2.93E+07 6.17E+06 - - - 6.7112 0.9997 221125_WJC_METTL3_EV_vs_WT_F07.11106.11106.4 9.00E-05 13/78 K.YDEELEGERPHSFR.L sp|O43290|SNUT1_HUMAN 1 1762.7911 2.44 98847 11106 4 1762.791773 441.705 U4\U6.U5 tri-snRNP-associated protein 1 OS=Homo sapiens OX=9606 GN=SART1 PE=1 SV=1 4.57 2160.9 - 2.50E+06 - - - 0.3948 - 2.281 0.346 - 108 1 2 0 0.0007 14 0 0 0 3.76E+07 1.54E+07 - - - 2.5375 1 221125_WJC_METTL3_EV_vs_WT_F07.11107.11107.3 2.44E-10 19/56 K.FELQHGTEEQQEEVR.K sp|O94906|PRP6_HUMAN 1 1857.8493 0.62 98848 11107 3 1857.848961 620.2904 Pre-mRNA-processing factor 6 OS=Homo sapiens OX=9606 GN=PRPF6 PE=1 SV=1 4.32 2161 - 2.39E+06 - - - -0.1932 - 3.856 0.629 - 593.2 1 2 0 -0.0004 15 0 0 0 9.30E+07 1.51E+08 - - - 9.0743 1 221125_WJC_METTL3_EV_vs_WT_F07.11108.11108.3 2.14E-08 16/72 K.VVQVSAGDSHTAALTDDGR.V "sp|P18754|RCC1_HUMAN,tr|C9JQZ4|C9JQZ4_HUMAN,tr|C9J3R0|C9J3R0_HUMAN,tr|C9JMJ4|C9JMJ4_HUMAN,tr|C9JW69|C9JW69_HUMAN,tr|C9JRH2|C9JRH2_HUMAN" 6 1897.913 0.71 98849 11108 3 1897.912288 633.6449 Regulator of chromosome condensation OS=Homo sapiens OX=9606 GN=RCC1 PE=1 SV=1 4.41 2161.1 - 1.26E+06 - - - -0.3662 - 3.476 0.679 - 265.9 1 2 0 -0.0007 19 0 0 0 4.86E+07 6.81E+07 - - - 9.1709 1 221125_WJC_METTL3_EV_vs_WT_F07.11109.11109.2 3.40E-09 17/20 R.HSEAFEALQQK[136.11].S sp|Q07065|CKAP4_HUMAN 1 1294.6397 1.49 98850 11109 2 1294.639945 648.3271 Cytoskeleton-associated protein 4 OS=Homo sapiens OX=9606 GN=CKAP4 PE=1 SV=2 5.4 2161.2 - 855853 - - - 0.1777 - 3.581 0.59 - 744.2 1 2 0 0.0002 11 0 0 0 2.60E+07 1.74E+07 - - - 6.8496 1 221125_WJC_METTL3_EV_vs_WT_F07.11110.11110.3 6.11E-10 18/68 A.AASASC[160.03]AHDPAAAAAALK.S sp|Q96F45|ZN503_HUMAN 1 1652.7941 0.13 98851 11110 3 1652.794643 551.9386 Zinc finger protein 503 OS=Homo sapiens OX=9606 GN=ZNF503 PE=1 SV=1 6.78 2161.4 - 607796 - - - 0.3564 - 3.307 0.635 - 374.1 1 1 0 0.0006 18 0 0 0 8.73E+06 6.85E+07 - - - 8.5977 1 221125_WJC_METTL3_EV_vs_WT_F07.11116.11116.3 1.09E-06 15/48 K.HLQHLAEVSAEVR.E "sp|O95229|ZWINT_HUMAN,tr|A6NH27|A6NH27_HUMAN" 2 1487.7845 4.09 98855 11116 3 1487.784149 496.9354 ZW10 interactor OS=Homo sapiens OX=9606 GN=ZWINT PE=1 SV=2 6 2162.1 - 1.88E+06 - - - -0.2191 - 3.083 0.481 - 471.7 1 2 0 -0.0003 13 0 0 0 2.96E+07 7.24E+06 - - - 6.9552 0.9993 221125_WJC_METTL3_EV_vs_WT_F07.11117.11117.3 5.46E-05 Nov-44 K.INNFSADIK[136.11]DSK[136.11].A sp|P13797|PLST_HUMAN 1 1366.7063 0.57 98856 11117 3 1366.705997 456.5761 Plastin-3 OS=Homo sapiens OX=9606 GN=PLS3 PE=1 SV=4 5.96 2162.1 - 853786 - - - -0.2546 - 2.222 0.361 - 178.4 1 2 1 -0.0003 12 0 0 0 1.67E+07 2.95E+07 - - - 4.7778 0.9083 221125_WJC_METTL3_EV_vs_WT_F07.11124.11124.3 0.138 Oct-48 K.ATFIK[136.11]VPQNQNGK[136.11].S "sp|P19338|NUCL_HUMAN,tr|A0A7I2V506|A0A7I2V506_HUMAN,tr|A0A7I2V699|A0A7I2V699_HUMAN,tr|A0A7I2V2U7|A0A7I2V2U7_HUMAN,tr|A0A7I2V3F3|A0A7I2V3F3_HUMAN,tr|A0A7I2V428|A0A7I2V428_HUMAN,tr|A0A7I2V349|A0A7I2V349_HUMAN,tr|H7BY16|H7BY16_HUMAN,tr|A0A7I2V5M5|A0A7I2V5M5_HUMAN,tr|C9JLB1|C9JLB1_HUMAN" 10 1459.8118 1.03 98861 11124 3 1459.812974 487.6112 Nucleolin OS=Homo sapiens OX=9606 GN=NCL PE=1 SV=3 10 2163 - 518590 - - - 0.7953 - 1.733 0.119 - 91 1 2 1 0.0012 13 0 0 0 1.42E+07 1.39E+07 - - - 1.3572 0.9998 221125_WJC_METTL3_EV_vs_WT_F07.11126.11126.3 6.04E-07 Dec-44 K.INNFSADIKDSK.A sp|P13797|PLST_HUMAN 1 1350.6779 0.56 98863 11126 3 1350.679896 451.2333 Plastin-3 OS=Homo sapiens OX=9606 GN=PLS3 PE=1 SV=4 5.96 2163.1 - 575036 - - - 1.4445 - 2.47 0.467 - 139.1 1 2 1 0.002 12 0 0 0 1.65E+07 2.95E+07 - - - 6.2524 0.9997 221125_WJC_METTL3_EV_vs_WT_F07.11127.11127.3 0.000625 13/36 K.AK[136.11]DPFAHLPK[136.11].S sp|P26641|EF1G_HUMAN 1 1138.647 0.001 98864 11127 3 1138.646906 380.5563 Elongation factor 1-gamma OS=Homo sapiens OX=9606 GN=EEF1G PE=1 SV=3 8.64 2163.2 - 462538 - - - -0.0641 - 2.096 0.455 - 163.7 1 2 1 -0.0001 10 0 0 0 0.00E+00 5.82E+07 - - - 5.774 0.9983 221125_WJC_METTL3_EV_vs_WT_F07.11133.11133.3 0.412 Aug-44 K.EENNHLQEELER[166.11].L "sp|Q15643|TRIPB_HUMAN,tr|H0YJ97|H0YJ97_HUMAN" 2 1548.7044 0.53 98868 11133 3 1548.705228 517.2421 Thyroid receptor-interacting protein 11 OS=Homo sapiens OX=9606 GN=TRIP11 PE=1 SV=3 4.32 2163.8 - 2.74E+06 - - - 0.545 - 1.654 0.27 - 104.8 1 2 0 0.0008 12 0 0 0 5.39E+07 1.01E+08 - - - 2.9448 0.9941 221125_WJC_METTL3_EV_vs_WT_F07.11134.11134.3 4.08E-06 Nov-48 Q.EFC[160.03]DYGTK[136.11]EEC[160.03]MK[136.11].A "sp|Q86U44|MTA70_HUMAN,tr|H0YFV6|H0YFV6_HUMAN" 2 1711.6863 0 98869 11134 3 1711.686163 571.5694 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 4.41 2163.9 - 3.40E+06 - - - -0.0684 - 2.717 0.593 - 153.8 1 1 1 -0.0001 13 0 0 0 1.32E+05 7.96E+07 - - - 7.8613 0.9967 221125_WJC_METTL3_EV_vs_WT_F07.11135.11135.3 0.0059 Sep-44 K.EIR[166.11]EDLPVNTSK[136.11].T "sp|Q86UE4|LYRIC_HUMAN,tr|E5RJU9|E5RJU9_HUMAN" 2 1417.7532 0.58 98870 11135 3 1417.754418 473.5917 Protein LYRIC OS=Homo sapiens OX=9606 GN=MTDH PE=1 SV=2 4.68 2164 - 497895 - - - 0.8746 - 2.048 0.274 - 142.2 1 2 1 0.0012 12 0 0 0 8.64E+06 1.49E+07 - - - 3.5815 0.992 221125_WJC_METTL3_EV_vs_WT_F07.11136.11136.3 0.275 Oct-40 R.SK[136.11]VDISQGIPK[136.11].Q "sp|Q96D46|NMD3_HUMAN,tr|C9IZW9|C9IZW9_HUMAN,tr|C9J0B9|C9J0B9_HUMAN,tr|C9IY70|C9IY70_HUMAN,tr|C9JA08|C9JA08_HUMAN,tr|C9K0C2|C9K0C2_HUMAN" 6 1186.6892 0.56 98871 11136 3 1186.687912 396.5704 60S ribosomal export protein NMD3 OS=Homo sapiens OX=9606 GN=NMD3 PE=1 SV=1 8.31 2164.1 - 484280 - - - -1.1174 - 1.586 0.279 - 105.6 1 2 1 -0.0013 11 0 0 0 5.38E+06 9.62E+06 - - - 2.9604 0.9997 221125_WJC_METTL3_EV_vs_WT_F07.11138.11138.2 1.78E-06 22-Oct K.EENNHLQEELER.L "sp|Q15643|TRIPB_HUMAN,tr|H0YJ97|H0YJ97_HUMAN" 2 1538.6961 1.65 98873 11138 2 1538.699444 770.3553 Thyroid receptor-interacting protein 11 OS=Homo sapiens OX=9606 GN=TRIP11 PE=1 SV=3 4.32 2164.3 - 439229 - - - 2.1642 - 1.913 0.556 - 237.3 1 2 0 0.0033 12 0 0 0 5.24E+06 3.17E+06 - - - 4.8533 0.9973 221125_WJC_METTL3_EV_vs_WT_F07.11141.11141.3 0.0329 Aug-36 R.KHEEFIATIR.A sp|Q96GY0|ZC21A_HUMAN 1 1242.6721 1.97 98876 11141 3 1242.671378 415.2313 Zinc finger C2HC domain-containing protein 1A OS=Homo sapiens OX=9606 GN=ZC2HC1A PE=1 SV=2 6.76 2164.7 - 284778 - - - -0.5577 - 1.558 0.25 - 73.7 1 2 0 -0.0007 10 0 0 0 1.77E+07 8.96E+06 - - - 2.622 0.9999 221125_WJC_METTL3_EV_vs_WT_F07.11145.11145.3 1.07E-05 15/48 K.ASLENSLEETKGR.Y "sp|P02533|K1C14_HUMAN,sp|P08779|K1C16_HUMAN,tr|K7ENW6|K7ENW6_HUMAN" 3 1432.7158 1070.59 98878 11145 3 1432.715631 478.5792 "Keratin, type I cytoskeletal 14 OS=Homo sapiens OX=9606 GN=KRT14 PE=1 SV=4" 4.79 2165.3 - 6.75E+06 - - - -0.1089 - 3.078 0.473 - 426.1 1 2 1 -0.0002 13 0 0 0 7.14E+08 6.67E+05 - - - 6.8617 0.9985 221125_WJC_METTL3_EV_vs_WT_F07.11148.11148.2 1.33E-06 13/32 R.ATGGGLSSVGGGSSTIK.Y sp|P04259|K2C6B_HUMAN 1 1434.7314 104.62 98881 11148 2 1434.731969 718.373 "Keratin, type II cytoskeletal 6B OS=Homo sapiens OX=9606 GN=KRT6B PE=1 SV=5" 8.8 2165.6 - 476743 - - - 0.3708 - 2.351 0.126 - 409.6 1 2 0 0.0005 17 0 0 0 3.25E+07 3.11E+05 - - - 2.0731 0.9621 221125_WJC_METTL3_EV_vs_WT_F07.11149.11149.3 8.19E-05 17/44 F.TTFDLGGHEQAR[166.11].R "sp|Q9NR31|SAR1A_HUMAN,tr|Q5SQT8|Q5SQT8_HUMAN" 2 1340.6348 1.51 98882 11149 3 1340.634227 447.8856 GTP-binding protein SAR1a OS=Homo sapiens OX=9606 GN=SAR1A PE=1 SV=1 5.29 2165.7 - 472227 - - - -0.4632 - 2.975 0.223 - 406.7 1 1 0 -0.0006 12 0 0 0 8.02E+06 5.32E+06 - - - 4.0481 1 221125_WJC_METTL3_EV_vs_WT_F07.11156.11156.3 6.13E-11 20/76 K.IVAERPGTNSTGPAPMAPPR.A "sp|Q13263|TIF1B_HUMAN,tr|M0R0K9|M0R0K9_HUMAN" 2 2018.0367 0.71 98887 11156 3 2018.037521 673.6862 Transcription intermediary factor 1-beta OS=Homo sapiens OX=9606 GN=TRIM28 PE=1 SV=5 9.6 2166.5 - 820871 - - - 0.385 - 3.899 0.666 - 419.6 1 2 0 0.0008 20 0 0 0 6.71E+07 9.45E+07 - - - 9.2662 0.9999 221125_WJC_METTL3_EV_vs_WT_F07.11158.11158.3 0.00643 13/52 K.K[136.11]FEEEGNPYYSSAR[166.11].V "sp|Q9HCC0|MCCB_HUMAN,tr|A0A804HJC1|A0A804HJC1_HUMAN,tr|A0A804HK37|A0A804HK37_HUMAN,tr|A0A804HJ24|A0A804HJ24_HUMAN,tr|A0A804HL02|A0A804HL02_HUMAN,tr|A0A804HKE8|A0A804HKE8_HUMAN,tr|A0A804HJ84|A0A804HJ84_HUMAN,tr|A0A804HLJ9|A0A804HLJ9_HUMAN,tr|A0A804HJL2|A0A804HJL2_HUMAN,tr|A0A804HJ31|A0A804HJ31_HUMAN" 10 1693.7703 1.38 98889 11158 3 1693.768772 565.5974 "Methylcrotonoyl-CoA carboxylase beta chain, mitochondrial OS=Homo sapiens OX=9606 GN=MCCC2 PE=1 SV=1" 4.79 2166.8 - 398911 - - - -0.8933 - 2.288 0.375 - 218.2 1 2 0 -0.0015 14 0 0 0 1.42E+07 1.03E+07 - - - 4.92 1 221125_WJC_METTL3_EV_vs_WT_F07.11160.11160.2 6.79E-09 Oct-32 R.SGGGAGSNGSVLDPAER.A "tr|E9PMV1|E9PMV1_HUMAN,tr|H0YDN1|H0YDN1_HUMAN" 2 1529.707 1.66 98891 11160 2 1529.704189 765.8608 Plectin (Fragment) OS=Homo sapiens OX=9606 GN=PLEC PE=1 SV=1 4.37 2167.1 - 270635 - - - -1.8461 - 2.446 0.651 - 142.3 1 2 0 -0.0028 17 0 0 0 5.78E+06 3.49E+06 - - - 6.0475 1 221125_WJC_METTL3_EV_vs_WT_F07.11165.11165.3 8.83E-07 13/56 K.FHPNSNYLATGSTDK.T sp|O75529|TAF5L_HUMAN 1 1650.7638 0.41 98894 11165 3 1650.764373 551.2619 TAF5-like RNA polymerase II p300\CBP-associated factor-associated factor 65 kDa subunit 5L OS=Homo sapiens OX=9606 GN=TAF5L PE=1 SV=1 6.74 2167.7 - 1.16E+06 - - - 0.3477 - 2.481 0.496 - 179.7 1 2 0 0.0006 15 0 0 0 2.17E+07 5.30E+07 - - - 6.4408 1 221125_WJC_METTL3_EV_vs_WT_F07.11167.11167.3 6.62E-11 18/60 K.LSTLLNHNNDTEEEER[166.11].L "sp|Q6KC79|NIPBL_HUMAN,tr|A0A590UJS4|A0A590UJS4_HUMAN" 2 1922.8845 1.44 98896 11167 3 1922.883862 641.9688 Nipped-B-like protein OS=Homo sapiens OX=9606 GN=NIPBL PE=1 SV=2 4.25 2168 - 857280 - - - -0.349 - 3.765 0.639 - 576.1 1 2 0 -0.0007 16 0 0 0 1.96E+07 1.36E+07 - - - 9.0657 0.976 221125_WJC_METTL3_EV_vs_WT_F07.11169.11169.3 0.000184 18/48 A.GK[136.11]AEELHYPLGER[166.11].R "sp|Q14257|RCN2_HUMAN,tr|H0YL43|H0YL43_HUMAN,tr|A8MXP8|A8MXP8_HUMAN" 3 1515.7801 0.78 98898 11169 3 1515.782718 506.2673 Reticulocalbin-2 OS=Homo sapiens OX=9606 GN=RCN2 PE=1 SV=1 5.5 2168.2 - 613646 - - - 1.7522 - 2.668 0.474 - 382.2 1 1 1 0.0027 13 0 0 0 1.77E+07 2.27E+07 - - - 6.4846 0.9306 221125_WJC_METTL3_EV_vs_WT_F07.11172.11172.2 4.07E-08 24-Nov Q.EFC[160.03]DYGTK[136.11]EEC[160.03]MK[136.11].A "sp|Q86U44|MTA70_HUMAN,tr|H0YFV6|H0YFV6_HUMAN" 2 1711.6863 0.001 98901 11172 2 1711.68519 856.8504 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 4.41 2168.6 - 381469 - - - -0.6368 - 2.137 0.561 - 347.8 1 1 1 -0.0011 13 0 0 0 0.00E+00 3.10E+06 - - - 5.1332 1 221125_WJC_METTL3_EV_vs_WT_F07.11177.11177.3 2.15E-07 13/48 K.NPSDSAVHSPFTK.R "sp|Q14157|UBP2L_HUMAN,tr|F8W726|F8W726_HUMAN" 2 1385.6575 2.37 98905 11177 3 1385.658539 462.8931 Ubiquitin-associated protein 2-like OS=Homo sapiens OX=9606 GN=UBAP2L PE=1 SV=2 6.74 2169.2 - 8.10E+07 - - - 0.7188 - 2.559 0.63 - 306.4 1 2 0 0.001 13 0 0 0 2.52E+09 1.07E+09 - - - 8.1112 1 221125_WJC_METTL3_EV_vs_WT_F07.11179.11179.3 6.70E-10 13/56 K.VHPEIINENGNPSYK[136.11].Y sp|O95881|TXD12_HUMAN 1 1717.8515 1.4 98906 11179 3 1717.848809 573.6244 Thioredoxin domain-containing protein 12 OS=Homo sapiens OX=9606 GN=TXNDC12 PE=1 SV=1 5.4 2169.4 - 5.15E+06 - - - -1.5659 - 2.787 0.645 - 282 1 2 0 -0.0027 15 0 0 0 1.85E+09 1.32E+09 - - - 8.4049 1 221125_WJC_METTL3_EV_vs_WT_F07.11180.11180.3 3.42E-08 16/56 K.VHPEIINENGNPSYK.Y sp|O95881|TXD12_HUMAN 1 1709.8373 1.4 98907 11180 3 1709.836464 570.953 Thioredoxin domain-containing protein 12 OS=Homo sapiens OX=9606 GN=TXNDC12 PE=1 SV=1 5.4 2169.5 - 5.56E+06 - - - -0.4884 - 2.796 0.578 - 388.5 1 2 0 -0.0008 15 0 0 0 1.85E+09 1.32E+09 - - - 7.6668 1 221125_WJC_METTL3_EV_vs_WT_F07.11182.11182.3 7.64E-07 21/76 K.IVAER[166.11]PGTNSTGPAPMAPPR[166.11].A "sp|Q13263|TIF1B_HUMAN,tr|M0R0K9|M0R0K9_HUMAN" 2 2038.0533 0.71 98909 11182 3 2038.051452 680.3584 Transcription intermediary factor 1-beta OS=Homo sapiens OX=9606 GN=TRIM28 PE=1 SV=5 9.6 2169.6 - 3.21E+06 - - - -0.8989 - 3.608 0.632 - 377.5 1 2 0 -0.0018 20 0 0 0 6.71E+07 9.45E+07 - - - 8.6986 0.9997 221125_WJC_METTL3_EV_vs_WT_F07.11183.11183.3 0.000392 13/56 R.HLYLR[166.11]GGAGVGSMTK[136.11].L sp|P39019|RS19_HUMAN 1 1563.8311 0.64 98910 11183 3 1563.830944 522.2843 40S ribosomal protein S19 OS=Homo sapiens OX=9606 GN=RPS19 PE=1 SV=2 9.99 2169.6 - 607673 - - - -0.0691 - 2.385 0.424 - 148.2 1 2 1 -0.0001 15 0 0 0 5.30E+06 8.31E+06 - - - 5.5352 1 221125_WJC_METTL3_EV_vs_WT_F07.11184.11184.3 4.18E-05 16/40 K.TPVEPEVAIHR.L "sp|P60866|RS20_HUMAN,tr|E5RJX2|E5RJX2_HUMAN,tr|E5RIP1|E5RIP1_HUMAN,tr|A0A7P0S5H5|A0A7P0S5H5_HUMAN" 4 1246.667 1.21 98911 11184 3 1246.66726 416.5629 40S ribosomal protein S20 OS=Homo sapiens OX=9606 GN=RPS20 PE=1 SV=1 5.37 2169.8 - 534194 - - - 0.2198 - 3.262 0.467 - 703.2 1 2 0 0.0003 11 0 0 0 1.95E+07 1.61E+07 - - - 7.1053 1 221125_WJC_METTL3_EV_vs_WT_F07.11189.11189.3 4.83E-08 13/48 K.NPSDSAVHSPFTK[136.11].R "sp|Q14157|UBP2L_HUMAN,tr|F8W726|F8W726_HUMAN" 2 1393.6717 2.87 98914 11189 3 1393.670495 465.5645 Ubiquitin-associated protein 2-like OS=Homo sapiens OX=9606 GN=UBAP2L PE=1 SV=2 6.74 2170.3 - 2.77E+07 - - - -0.8955 - 2.702 0.635 - 253.2 1 2 0 -0.0012 13 0 0 0 3.57E+09 1.24E+09 - - - 8.3143 1 221125_WJC_METTL3_EV_vs_WT_F07.11191.11191.3 4.17E-10 17/52 K.DMYNDTLNGSTEKR.S sp|Q96PU8|QKI_HUMAN 1 1642.7257 3.28 98916 11191 3 1642.724711 548.5825 Protein quaking OS=Homo sapiens OX=9606 GN=QKI PE=1 SV=1 4.56 2170.4 - 5.07E+06 - - - -0.6014 - 3.366 0.713 - 343.4 1 2 0 -0.001 14 0 0 0 6.75E+07 2.06E+07 - - - 9.7145 0.9824 221125_WJC_METTL3_EV_vs_WT_F07.11192.11192.4 0.171 13/96 K.FMSVQRPGPYDRPGTAR.R sp|P52597|HNRPF_HUMAN 1 1933.9581 0.77 98917 11192 4 1933.957214 484.4968 Heterogeneous nuclear ribonucleoprotein F OS=Homo sapiens OX=9606 GN=HNRNPF PE=1 SV=3 10.74 2170.5 - 2.49E+06 - - - -0.4576 - 1.759 0.178 - 87.5 1 2 0 -0.0009 17 0 0 0 3.81E+08 4.97E+08 - - - 0.9711 1 221125_WJC_METTL3_EV_vs_WT_F07.11193.11193.3 7.37E-07 19/60 K.LSTLLNHNNDTEEEER.L "sp|Q6KC79|NIPBL_HUMAN,tr|A0A590UJS4|A0A590UJS4_HUMAN" 2 1912.8763 1.44 98918 11193 3 1912.876724 638.6327 Nipped-B-like protein OS=Homo sapiens OX=9606 GN=NIPBL PE=1 SV=2 4.25 2170.6 - 1.64E+06 - - - 0.241 - 3.225 0.478 - 633.8 1 2 0 0.0005 16 0 0 0 1.96E+07 1.36E+07 - - - 6.8736 0.9999 221125_WJC_METTL3_EV_vs_WT_F07.11195.11195.3 6.51E-06 14/52 K.KFEEEGNPYYSSAR.V "sp|Q9HCC0|MCCB_HUMAN,tr|A0A804HJC1|A0A804HJC1_HUMAN,tr|A0A804HK37|A0A804HK37_HUMAN,tr|A0A804HJ24|A0A804HJ24_HUMAN,tr|A0A804HL02|A0A804HL02_HUMAN,tr|A0A804HKE8|A0A804HKE8_HUMAN,tr|A0A804HJ84|A0A804HJ84_HUMAN,tr|A0A804HLJ9|A0A804HLJ9_HUMAN,tr|A0A804HJL2|A0A804HJL2_HUMAN,tr|A0A804HJ31|A0A804HJ31_HUMAN" 10 1675.7478 1.48 98920 11195 3 1675.750022 559.5899 "Methylcrotonoyl-CoA carboxylase beta chain, mitochondrial OS=Homo sapiens OX=9606 GN=MCCC2 PE=1 SV=1" 4.79 2170.7 - 1.20E+06 - - - 1.317 - 2.058 0.448 - 233.6 1 2 0 0.0022 14 0 0 0 1.54E+07 1.04E+07 - - - 5.4522 1 221125_WJC_METTL3_EV_vs_WT_F07.11197.11197.2 1.06E-13 20/36 K.GAEAANVTGPGGVPVQGSK.Y "sp|P67809|YBOX1_HUMAN,tr|H0Y449|H0Y449_HUMAN,tr|C9J5V9|C9J5V9_HUMAN" 3 1694.8588 1.14 98922 11197 2 1694.858459 848.4367 Y-box-binding protein 1 OS=Homo sapiens OX=9606 GN=YBX1 PE=1 SV=3 6 2170.9 - 701088 - - - -0.1794 - 3.828 0.724 - 871.3 1 2 0 -0.0003 19 0 0 0 1.28E+09 1.12E+09 - - - 7.6886 1 221125_WJC_METTL3_EV_vs_WT_F07.11198.11198.2 2.80E-09 17/28 K.VHPEIINENGNPSYK.Y sp|O95881|TXD12_HUMAN 1 1709.8373 0.91 98923 11198 2 1709.831677 855.9259 Thioredoxin domain-containing protein 12 OS=Homo sapiens OX=9606 GN=TXNDC12 PE=1 SV=1 5.4 2171.1 - 695572 - - - -3.288 - 3.051 0.692 - 553.1 1 2 0 -0.0056 15 0 0 0 1.04E+08 1.15E+08 - - - 6.8928 1 221125_WJC_METTL3_EV_vs_WT_F07.11199.11199.2 9.23E-10 20/36 K.GAEAANVTGPGGVPVQGSK[136.11].Y "sp|P67809|YBOX1_HUMAN,tr|H0Y449|H0Y449_HUMAN,tr|C9J5V9|C9J5V9_HUMAN" 3 1702.873 1.14 98924 11199 2 1702.871379 852.4438 Y-box-binding protein 1 OS=Homo sapiens OX=9606 GN=YBX1 PE=1 SV=3 6 2171.2 - 646453 - - - -0.9302 - 3.836 0.605 - 731.6 1 2 0 -0.0016 19 0 0 0 1.28E+09 1.12E+09 - - - 6.8144 1 221125_WJC_METTL3_EV_vs_WT_F07.11201.11201.2 7.96E-07 16/28 K.VHPEIINENGNPSYK[136.11].Y sp|O95881|TXD12_HUMAN 1 1717.8515 0.91 98926 11201 2 1717.849265 859.933 Thioredoxin domain-containing protein 12 OS=Homo sapiens OX=9606 GN=TXNDC12 PE=1 SV=1 5.4 2171.4 - 596089 - - - -1.3005 - 2.938 0.633 - 504.2 1 2 0 -0.0022 15 0 0 0 1.04E+08 1.15E+08 - - - 6.3653 1 221125_WJC_METTL3_EV_vs_WT_F07.11205.11205.2 7.18E-08 26-Dec K.DMYNDTLNGSTEKR.S sp|Q96PU8|QKI_HUMAN 1 1642.7257 4.67 98930 11205 2 1642.729099 822.3701 Protein quaking OS=Homo sapiens OX=9606 GN=QKI PE=1 SV=1 4.56 2171.9 - 265687 - - - 2.0697 - 2.91 0.727 - 418.2 1 2 0 0.0034 14 0 0 0 3.18E+06 6.81E+05 - - - 7.09 0.9969 221125_WJC_METTL3_EV_vs_WT_F07.11208.11208.4 0.0552 Dec-96 K.FMSVQR[166.11]PGPYDR[166.11]PGTAR[166.11].R sp|P52597|HNRPF_HUMAN 1 1963.9829 0.77 98931 11208 4 1963.981206 492.003 Heterogeneous nuclear ribonucleoprotein F OS=Homo sapiens OX=9606 GN=HNRNPF PE=1 SV=3 10.74 2172.3 - 6.95E+06 - - - -0.8671 - 1.696 0.252 - 69 1 2 0 -0.0017 17 0 0 0 3.81E+08 4.97E+08 - - - 1.6024 1 221125_WJC_METTL3_EV_vs_WT_F07.11209.11209.2 3.37E-07 24-Nov K.NPSDSAVHSPFTK.R "sp|Q14157|UBP2L_HUMAN,tr|F8W726|F8W726_HUMAN" 2 1385.6575 2.4 98932 11209 2 1385.656448 693.836 Ubiquitin-associated protein 2-like OS=Homo sapiens OX=9606 GN=UBAP2L PE=1 SV=2 6.74 2172.4 - 4.84E+06 - - - -0.7902 - 2.567 0.607 - 536.8 1 2 0 -0.0011 13 0 0 0 3.43E+08 1.43E+08 - - - 5.9435 1 221125_WJC_METTL3_EV_vs_WT_F07.11211.11211.3 1.24E-07 13/52 K.DMYNDTLNGSTEK[136.11]R[166.11].S sp|Q96PU8|QKI_HUMAN 1 1660.7482 3.32 98934 11211 3 1660.749665 554.59 Protein quaking OS=Homo sapiens OX=9606 GN=QKI PE=1 SV=1 4.56 2172.5 - 1.99E+06 - - - 0.9008 - 2.358 0.622 - 146.1 1 2 0 0.0015 14 0 0 0 6.75E+07 2.03E+07 - - - 7.7539 0.9998 221125_WJC_METTL3_EV_vs_WT_F07.11212.11212.3 7.98E-07 13/48 K.SGDK[136.11]NDDGLVEIK[136.11].V tr|A8MXP9|A8MXP9_HUMAN 1 1404.7067 1.54 98935 11212 3 1404.704155 469.2429 Matrin-3 OS=Homo sapiens OX=9606 GN=MATR3 PE=1 SV=1 4.23 2172.5 - 1.99E+06 - - - -1.8388 - 2.34 0.507 - 256 1 2 1 -0.0026 13 0 0 0 6.35E+08 4.11E+08 - - - 6.4968 0.9976 221125_WJC_METTL3_EV_vs_WT_F07.11213.11213.3 0.00277 Nov-64 K.FMSVQR[166.11]PGPYDR[166.11]PGTAR[166.11].R sp|P52597|HNRPF_HUMAN 1 1963.9829 0.79 98936 11213 3 1963.979702 655.6682 Heterogeneous nuclear ribonucleoprotein F OS=Homo sapiens OX=9606 GN=HNRNPF PE=1 SV=3 10.74 2172.6 - 1.95E+06 - - - -1.6329 - 1.557 0.295 - 46.9 1 2 0 -0.0032 17 0 0 0 1.20E+08 1.52E+08 - - - 2.9466 1 221125_WJC_METTL3_EV_vs_WT_F07.11214.11214.3 1.88E-08 21/48 K.NDFTEEEEAQVR[166.11]K[136.11].E "sp|P63208|SKP1_HUMAN,tr|E5RJR5|E5RJR5_HUMAN" 2 1611.7495 0.84 98937 11214 3 1611.748904 538.2571 S-phase kinase-associated protein 1 OS=Homo sapiens OX=9606 GN=SKP1 PE=1 SV=2 4.25 2172.7 - 1.25E+06 - - - -0.4008 - 3.63 0.61 - 813.3 1 2 0 -0.0006 13 0 0 0 1.40E+07 1.68E+07 - - - 8.8362 0.8565 221125_WJC_METTL3_EV_vs_WT_F07.11216.11216.2 0.15 18-Oct L.ENSLEETKGR.Y "sp|P02533|K1C14_HUMAN,sp|P08779|K1C16_HUMAN,tr|K7ENW6|K7ENW6_HUMAN" 3 1161.5626 999 98939 11216 2 1161.563602 581.7886 "Keratin, type I cytoskeletal 14 OS=Homo sapiens OX=9606 GN=KRT14 PE=1 SV=4" 4.79 2172.9 - 711379 - - - 0.8798 - 2.109 0.402 - 427 1 1 1 0.001 10 0 0 0 9.33E+06 0.00E+00 - - - 4.0928 1 221125_WJC_METTL3_EV_vs_WT_F07.11222.11222.3 2.10E-06 14/44 K.C[160.03]YSC[160.03]GEFGHIQK.D sp|P62633|CNBP_HUMAN 1 1484.6177 1.02 98943 11222 3 1484.616867 495.8798 CCHC-type zinc finger nucleic acid binding protein OS=Homo sapiens OX=9606 GN=CNBP PE=1 SV=1 6.73 2173.7 - 6.24E+06 - - - -0.5409 - 1.918 0.628 - 218 1 2 0 -0.0008 12 0 0 0 1.88E+08 1.84E+08 - - - 7.3466 0.9999 221125_WJC_METTL3_EV_vs_WT_F07.11225.11225.3 1.72E-06 14/48 K.SEEQLKEEGIEYK.V "sp|P09622|DLDH_HUMAN,tr|E9PEX6|E9PEX6_HUMAN" 2 1580.757 2.13 98946 11225 3 1580.757631 527.9263 "Dihydrolipoyl dehydrogenase, mitochondrial OS=Homo sapiens OX=9606 GN=DLD PE=1 SV=2" 4.32 2174 - 1.28E+06 - - - 0.4099 - 2.713 0.553 - 276.9 1 2 1 0.0006 13 0 0 0 4.91E+07 2.31E+07 - - - 7.4112 1 221125_WJC_METTL3_EV_vs_WT_F07.11230.11230.2 5.39E-11 13/22 K.C[160.03]YSC[160.03]GEFGHIQK[136.11].D sp|P62633|CNBP_HUMAN 1 1492.6319 0.68 98951 11230 2 1492.630393 747.3232 CCHC-type zinc finger nucleic acid binding protein OS=Homo sapiens OX=9606 GN=CNBP PE=1 SV=1 6.73 2174.6 - 612210 - - - -0.9895 - 2.375 0.777 - 394.3 1 2 0 -0.0015 12 0 0 0 8.48E+06 1.24E+07 - - - 7.0554 0.9999 221125_WJC_METTL3_EV_vs_WT_F07.11231.11231.2 1.64E-07 Sep-34 K.GPASTPTYSPAPTQPAPR[166.11].L "sp|Q6P1N0|C2D1A_HUMAN,tr|K7EJY5|K7EJY5_HUMAN" 2 1804.8983 1.11 98952 11231 2 1804.897957 903.4564 Coiled-coil and C2 domain-containing protein 1A OS=Homo sapiens OX=9606 GN=CC2D1A PE=1 SV=1 8.75 2174.7 - 279385 - - - -0.2083 - 2.054 0.622 - 140.7 1 2 0 -0.0004 18 0 0 0 2.39E+06 2.15E+06 - - - 5.4046 0.9999 221125_WJC_METTL3_EV_vs_WT_F07.11235.11235.3 5.40E-05 17/44 K.C[160.03]RIEISSPC[160.03]C[160.03]PR.Q sp|Q5T749|KPRP_HUMAN 1 1533.685 398.54 98954 11235 3 1533.682658 512.2356 Keratinocyte proline-rich protein OS=Homo sapiens OX=9606 GN=KPRP PE=1 SV=1 7.97 2175.2 - 819562 - - - -1.5518 - 2.8 0.516 - 600.3 1 2 1 -0.0024 12 0 0 0 1.21E+08 3.02E+05 - - - 7.1462 0.9996 221125_WJC_METTL3_EV_vs_WT_F07.11237.11237.3 0.0235 16/52 K.YSNSALGHVNC[160.03]TIK[136.11].E "sp|Q9NQC3|RTN4_HUMAN,tr|A0A0U1RQR6|A0A0U1RQR6_HUMAN,tr|F8W914|F8W914_HUMAN,tr|H7C106|H7C106_HUMAN" 4 1570.7653 1.74 98956 11237 3 1570.765226 524.5957 Reticulon-4 OS=Homo sapiens OX=9606 GN=RTN4 PE=1 SV=2 8.21 2175.3 - 1.05E+06 - - - -0.0643 - 2.184 0.309 - 151.5 1 2 0 -0.0001 14 0 0 0 2.45E+07 1.40E+07 - - - 4.061 1 221125_WJC_METTL3_EV_vs_WT_F07.11239.11239.3 4.64E-07 15/52 K.YSNSALGHVNC[160.03]TIK.E "sp|Q9NQC3|RTN4_HUMAN,tr|A0A0U1RQR6|A0A0U1RQR6_HUMAN,tr|F8W914|F8W914_HUMAN,tr|H7C106|H7C106_HUMAN" 4 1562.7511 1.28 98958 11239 3 1562.7468 521.9243 Reticulon-4 OS=Homo sapiens OX=9606 GN=RTN4 PE=1 SV=2 8.21 2175.6 - 839165 - - - -2.7688 - 2.837 0.57 - 141 1 2 0 -0.0043 14 0 0 0 1.52E+07 1.18E+07 - - - 7.6649 0.9999 221125_WJC_METTL3_EV_vs_WT_F07.11243.11243.4 5.21E-07 16/72 K.NLDDTIDDEKLRK.E "sp|Q13310|PABP4_HUMAN,tr|A0A7I2V5W9|A0A7I2V5W9_HUMAN,tr|H0YEU6|H0YEU6_HUMAN,tr|B1ANR0|B1ANR0_HUMAN,tr|A0A7I2V4L7|A0A7I2V4L7_HUMAN,tr|A0A7I2V598|A0A7I2V598_HUMAN,tr|H0Y5F5|H0Y5F5_HUMAN" 7 1573.7948 1.49 98962 11243 4 1573.793405 394.456 Polyadenylate-binding protein 4 OS=Homo sapiens OX=9606 GN=PABPC4 PE=1 SV=1 4.36 2176.1 - 342171 - - - -0.8642 - 2.743 0.517 - 270.2 1 2 1 -0.0014 13 0 0 0 2.01E+07 1.35E+07 - - - 4.0997 0.9999 221125_WJC_METTL3_EV_vs_WT_F07.11248.11248.3 0.000927 14/60 R.DREEDGGGLEPAAVAR.D sp|Q96EU6|RRP36_HUMAN 1 1640.7754 0.95 98965 11248 3 1640.775018 547.9324 Ribosomal RNA processing protein 36 homolog OS=Homo sapiens OX=9606 GN=RRP36 PE=1 SV=1 4.18 2176.6 - 2.43E+06 - - - -0.2493 - 2.77 0.559 - 243.9 1 2 1 -0.0004 16 0 0 0 6.44E+07 6.81E+07 - - - 7.3864 0.9968 221125_WJC_METTL3_EV_vs_WT_F07.11260.11260.3 8.76E-05 Nov-48 K.SGDKNDDGLVEIK.V tr|A8MXP9|A8MXP9_HUMAN 1 1388.6783 1.51 98973 11260 3 1388.677058 463.9001 Matrin-3 OS=Homo sapiens OX=9606 GN=MATR3 PE=1 SV=1 4.23 2177.9 - 2.45E+07 - - - -0.9217 - 1.93 0.291 - 185 1 2 1 -0.0013 13 0 0 0 6.20E+08 4.11E+08 - - - 3.5667 0.8495 221125_WJC_METTL3_EV_vs_WT_F07.11263.11263.2 0.000726 22-Oct S.GDKNDDGLVEIK.V tr|A8MXP9|A8MXP9_HUMAN 1 1301.6463 13.35 98976 11263 2 1301.648041 651.8304 Matrin-3 OS=Homo sapiens OX=9606 GN=MATR3 PE=1 SV=1 4.23 2178.3 - 255847 - - - 1.3299 - 2.014 0.466 - 218.5 1 1 1 0.0017 12 0 0 0 2.75E+06 2.06E+05 - - - 4.3245 1 221125_WJC_METTL3_EV_vs_WT_F07.11271.11271.3 2.94E-06 16/40 R.KNHEEEMLALR.G "sp|P08779|K1C16_HUMAN,tr|K7ENW6|K7ENW6_HUMAN" 2 1368.682 14857.34 98981 11271 3 1368.683793 457.2346 "Keratin, type I cytoskeletal 16 OS=Homo sapiens OX=9606 GN=KRT16 PE=1 SV=4" 5.5 2179.1 - 2.66E+06 - - - 1.3217 - 3.045 0.54 - 480.6 1 2 0 0.0018 11 0 0 0 1.38E+09 9.31E+04 - - - 7.7232 0.9984 221125_WJC_METTL3_EV_vs_WT_F07.11272.11272.3 0.00697 Nov-48 R.SGISTGHWSGEVK.D "sp|Q9BYC5|FUT8_HUMAN,tr|G3XAD2|G3XAD2_HUMAN,tr|A0A669KAW1|A0A669KAW1_HUMAN" 3 1343.647 0.89 98982 11272 3 1343.642695 448.8896 "Alpha-(1,6)-fucosyltransferase OS=Homo sapiens OX=9606 GN=FUT8 PE=1 SV=2" 6.47 2179.2 - 620047 - - - -3.1883 - 2 0.328 - 140.3 1 2 0 -0.0043 13 0 0 0 1.10E+07 1.23E+07 - - - 4.075 1 221125_WJC_METTL3_EV_vs_WT_F07.11274.11274.2 4.08E-06 15/24 K.SGDK[136.11]NDDGLVEIK[136.11].V tr|A8MXP9|A8MXP9_HUMAN 1 1404.7067 1.39 98983 11274 2 1404.705535 703.3606 Matrin-3 OS=Homo sapiens OX=9606 GN=MATR3 PE=1 SV=1 4.23 2179.4 - 1.79E+06 - - - -0.8564 - 2.911 0.557 - 607 1 2 1 -0.0012 13 0 0 0 9.43E+07 6.80E+07 - - - 5.897 0.9612 221125_WJC_METTL3_EV_vs_WT_F07.11290.11290.3 0.0745 Oct-64 K.FMSVQRPGPYDRPGTAR.R sp|P52597|HNRPF_HUMAN 1 1933.9581 0.79 98993 11290 3 1933.955226 645.66 Heterogeneous nuclear ribonucleoprotein F OS=Homo sapiens OX=9606 GN=HNRNPF PE=1 SV=3 10.74 2181.3 - 3.74E+06 - - - -1.4856 - 1.326 0.17 - 29.3 1 2 0 -0.0029 17 0 0 0 1.20E+08 1.52E+08 - - - 1.1474 1 221125_WJC_METTL3_EV_vs_WT_F07.11293.11293.3 2.01E-08 18/68 R.AALAHSEEVTASQVAATK.T "sp|Q15149|PLEC_HUMAN,tr|H0YDN1|H0YDN1_HUMAN" 2 1782.9112 1.74 98996 11293 3 1782.908543 595.311 Plectin OS=Homo sapiens OX=9606 GN=PLEC PE=1 SV=3 5.4 2181.4 - 3.16E+06 - - - -1.4858 - 3.266 0.621 - 472 1 2 0 -0.0026 18 0 0 0 5.82E+07 3.36E+07 - - - 8.41 0.9999 221125_WJC_METTL3_EV_vs_WT_F07.11294.11294.2 0.0673 15/20 R.KNHEEEMLALR.G "sp|P08779|K1C16_HUMAN,tr|K7ENW6|K7ENW6_HUMAN" 2 1368.682 999 98997 11294 2 1368.679975 685.3483 "Keratin, type I cytoskeletal 16 OS=Homo sapiens OX=9606 GN=KRT16 PE=1 SV=4" 5.5 2181.6 - 919020 - - - -1.4678 - 2.708 0.49 - 1002 1 2 0 -0.002 11 0 0 0 7.94E+07 0.00E+00 - - - 5.3545 1 221125_WJC_METTL3_EV_vs_WT_F07.11297.11297.3 6.74E-11 20/72 K.GAEAANVTGPGGVPVQGSK.Y "sp|P67809|YBOX1_HUMAN,tr|H0Y449|H0Y449_HUMAN,tr|C9J5V9|C9J5V9_HUMAN" 3 1694.8588 1.22 98999 11297 3 1694.857678 565.9602 Y-box-binding protein 1 OS=Homo sapiens OX=9606 GN=YBX1 PE=1 SV=3 6 2181.9 - 1.53E+07 - - - -0.6402 - 3.672 0.526 - 208.2 1 2 0 -0.0011 19 0 0 0 5.08E+08 4.16E+08 - - - 7.5997 1 221125_WJC_METTL3_EV_vs_WT_F07.11300.11300.2 8.00E-09 16/26 K.SSGASVTTQPTEFK[136.11].L "sp|Q9BY77|PDIP3_HUMAN,tr|F6VRR5|F6VRR5_HUMAN" 2 1446.7082 1.46 99001 11300 2 1446.708143 724.3614 Polymerase delta-interacting protein 3 OS=Homo sapiens OX=9606 GN=POLDIP3 PE=1 SV=2 5.72 2182.2 - 1.48E+06 - - - -0.0318 - 2.811 0.619 - 851.5 1 2 0 0 14 0 0 0 4.48E+08 3.08E+08 - - - 6.2065 0.9999 221125_WJC_METTL3_EV_vs_WT_F07.11303.11303.3 3.48E-05 21/60 K.LPSR[166.11]PGAQGVEPQNLR[166.11].T "sp|Q8WXI9|P66B_HUMAN,tr|A0A0U1RRM1|A0A0U1RRM1_HUMAN" 2 1737.9389 1.92 99004 11303 3 1737.934909 580.3202 Transcriptional repressor p66-beta OS=Homo sapiens OX=9606 GN=GATAD2B PE=1 SV=1 9.6 2182.6 - 917660 - - - -2.2999 - 3.535 0.437 - 531.7 1 2 0 -0.004 16 0 0 0 2.74E+08 1.43E+08 - - - 6.651 0.9981 221125_WJC_METTL3_EV_vs_WT_F07.11306.11306.2 0.006 22-Nov R.QTVEADVNGLRR.V sp|P08779|K1C16_HUMAN 1 1356.711 301.59 99005 11306 2 1356.708387 679.3628 "Keratin, type I cytoskeletal 16 OS=Homo sapiens OX=9606 GN=KRT16 PE=1 SV=4" 6.07 2182.9 - 853588 - - - -1.9083 - 1.655 0.281 - 156.5 1 2 0 -0.0026 12 0 0 0 1.45E+08 4.79E+05 - - - 2.4412 1 221125_WJC_METTL3_EV_vs_WT_F07.11313.11313.3 1.03E-08 14/72 K.GAEAANVTGPGGVPVQGSK[136.11].Y "sp|P67809|YBOX1_HUMAN,tr|H0Y449|H0Y449_HUMAN,tr|C9J5V9|C9J5V9_HUMAN" 3 1702.873 1.24 99010 11313 3 1702.870459 568.6316 Y-box-binding protein 1 OS=Homo sapiens OX=9606 GN=YBX1 PE=1 SV=3 6 2183.8 - 1.26E+07 - - - -1.4705 - 3.229 0.646 - 132.4 1 2 0 -0.0025 19 0 0 0 5.07E+08 4.07E+08 - - - 8.6214 0.9999 221125_WJC_METTL3_EV_vs_WT_F07.11315.11315.3 0.000376 15/64 K.QVSQAQTTVQPSATLQR[166.11].S sp|O00268|TAF4_HUMAN 1 1851.9678 1.63 99012 11315 3 1851.965606 618.3299 Transcription initiation factor TFIID subunit 4 OS=Homo sapiens OX=9606 GN=TAF4 PE=1 SV=2 9.75 2184 - 590693 - - - -1.1895 - 2.839 0.394 - 183.1 1 2 0 -0.0022 17 0 0 0 3.19E+07 1.96E+07 - - - 5.5682 1 221125_WJC_METTL3_EV_vs_WT_F07.11320.11320.3 7.82E-07 23/68 R.APEQRPAPNAAPVDPTLR.T "sp|Q6P1J9|CDC73_HUMAN,tr|A0A2R8YHB3|A0A2R8YHB3_HUMAN,tr|A0A3B3IRP5|A0A3B3IRP5_HUMAN" 3 1898.9963 1.6 99015 11320 3 1898.993522 634.006 Parafibromin OS=Homo sapiens OX=9606 GN=CDC73 PE=1 SV=1 6.12 2184.6 - 1.02E+06 - - - -1.4413 - 3.891 0.526 - 520.3 1 2 0 -0.0027 18 0 0 0 1.39E+08 8.71E+07 - - - 7.7868 0.9999 221125_WJC_METTL3_EV_vs_WT_F07.11323.11323.3 0.00739 20/64 K.QVSQAQTTVQPSATLQR.S sp|O00268|TAF4_HUMAN 1 1841.9595 1.63 99016 11323 3 1841.960748 614.9938 Transcription initiation factor TFIID subunit 4 OS=Homo sapiens OX=9606 GN=TAF4 PE=1 SV=2 9.75 2185 - 1.66E+06 - - - 0.6564 - 3.122 0.35 - 222.2 1 2 0 0.0012 17 0 0 0 3.19E+07 1.96E+07 - - - 5.3179 1 221125_WJC_METTL3_EV_vs_WT_F07.11330.11330.3 8.66E-08 17/60 K.LPSRPGAQGVEPQNLR.T "sp|Q8WXI9|P66B_HUMAN,tr|A0A0U1RRM1|A0A0U1RRM1_HUMAN" 2 1717.9224 1.92 99021 11330 3 1717.920942 573.6481 Transcriptional repressor p66-beta OS=Homo sapiens OX=9606 GN=GATAD2B PE=1 SV=1 9.6 2185.9 - 7.26E+06 - - - -0.8289 - 2.981 0.536 - 280.6 1 2 0 -0.0014 16 0 0 0 2.74E+08 1.43E+08 - - - 7.3181 1 221125_WJC_METTL3_EV_vs_WT_F07.11332.11332.3 1.46E-09 22/68 R.APEQR[166.11]PAPNAAPVDPTLR[166.11].T "sp|Q6P1J9|CDC73_HUMAN,tr|A0A2R8YHB3|A0A2R8YHB3_HUMAN,tr|A0A3B3IRP5|A0A3B3IRP5_HUMAN" 3 1919.0128 1.6 99022 11332 3 1919.0104 640.6782 Parafibromin OS=Homo sapiens OX=9606 GN=CDC73 PE=1 SV=1 6.12 2186.1 - 2.40E+06 - - - -1.2501 - 3.185 0.619 - 418.3 1 2 0 -0.0024 18 0 0 0 1.39E+08 8.71E+07 - - - 8.3252 1 221125_WJC_METTL3_EV_vs_WT_F07.11336.11336.2 1.38E-10 20/32 K.QVSQAQTTVQPSATLQR.S sp|O00268|TAF4_HUMAN 1 1841.9595 1.67 99026 11336 2 1841.95772 921.987 Transcription initiation factor TFIID subunit 4 OS=Homo sapiens OX=9606 GN=TAF4 PE=1 SV=2 9.75 2186.6 - 801274 - - - -0.9875 - 3.586 0.668 - 1037.4 1 2 0 -0.0018 17 0 0 0 1.40E+07 8.38E+06 - - - 7.1139 1 221125_WJC_METTL3_EV_vs_WT_F07.11340.11340.2 0.000121 15/26 K.SSGASVTTQPTEFK.L "sp|Q9BY77|PDIP3_HUMAN,tr|F6VRR5|F6VRR5_HUMAN" 2 1438.694 1.46 99028 11340 2 1438.693386 720.3543 Polymerase delta-interacting protein 3 OS=Homo sapiens OX=9606 GN=POLDIP3 PE=1 SV=2 5.72 2187.1 - 2.20E+07 - - - -0.4191 - 2.934 0.57 - 753.8 1 2 0 -0.0006 14 0 0 0 4.49E+08 3.08E+08 - - - 5.9519 0.9234 221125_WJC_METTL3_EV_vs_WT_F07.11343.11343.4 0.158 Jul-72 K.DLEEDHAC[160.03]IPIK[136.11]K[136.11].S sp|P13639|EF2_HUMAN 1 1582.7996 0.35 99031 11343 4 1582.795843 396.7072 Elongation factor 2 OS=Homo sapiens OX=9606 GN=EEF2 PE=1 SV=4 4.75 2187.4 - 874709 - - - -2.3692 - 1.268 0.199 - 27.6 3 2 0 -0.0038 13 0 0 0 2.30E+07 6.66E+07 - - - 0.6815 0.995 221125_WJC_METTL3_EV_vs_WT_F07.11347.11347.3 0.00737 Aug-52 R.LRQEEPQSLQAAVR.T "sp|P29590|PML_HUMAN,tr|H3BUJ5|H3BUJ5_HUMAN,tr|H3BT29|H3BT29_HUMAN,tr|H3BVD2|H3BVD2_HUMAN,tr|H3BT57|H3BT57_HUMAN" 5 1623.8693 0.82 99033 11347 3 1623.869218 542.297 Protein PML OS=Homo sapiens OX=9606 GN=PML PE=1 SV=3 6.14 2187.9 - 1.11E+06 - - - -0.0308 - 1.805 0.282 - 89.1 1 2 1 -0.0001 14 0 0 0 1.25E+07 1.53E+07 - - - 3.2534 1 221125_WJC_METTL3_EV_vs_WT_F07.11348.11348.3 4.87E-06 14/48 K.DLEEDHAC[160.03]IPIK[136.11]K[136.11].S sp|P13639|EF2_HUMAN 1 1582.7996 0.42 99034 11348 3 1582.796782 528.6071 Elongation factor 2 OS=Homo sapiens OX=9606 GN=EEF2 PE=1 SV=4 4.75 2188 - 1.24E+06 - - - -1.776 - 2.61 0.603 - 158.1 1 2 0 -0.0028 13 0 0 0 2.33E+07 5.54E+07 - - - 7.8632 1 221125_WJC_METTL3_EV_vs_WT_F07.11353.11353.3 0.000153 13/52 R.FGQGVHHGLSEGWK.E "sp|Q6UWP8|SBSN_HUMAN,sp|Q6UWP8|SBSN_HUMAN" 2 1537.7426 2.99 99037 11353 3 1537.741887 513.5881 Suprabasin OS=Homo sapiens OX=9606 GN=SBSN PE=1 SV=2 6.92 2188.6 - 2.73E+06 - - - -0.4702 - 2.938 0.478 - 118.7 1 2 0 -0.0007 14 0 0 0 4.63E+07 1.55E+07 - - - 6.7331 0.9995 221125_WJC_METTL3_EV_vs_WT_F07.11354.11354.3 0.00244 14/56 K.QANKEYLLGSTAEEK.A "sp|O43324|MCA3_HUMAN,tr|C9J1V9|C9J1V9_HUMAN,tr|H0YAL7|H0YAL7_HUMAN,tr|D6RBD7|D6RBD7_HUMAN,tr|D6RCQ0|D6RCQ0_HUMAN" 5 1679.8366 0.08 99038 11354 3 1679.837202 560.9528 Eukaryotic translation elongation factor 1 epsilon-1 OS=Homo sapiens OX=9606 GN=EEF1E1 PE=1 SV=1 4.79 2188.8 - 948588 - - - 0.3405 - 1.998 0.436 - 239.8 1 2 1 0.0006 15 0 0 0 3.41E+07 4.42E+08 - - - 5.2069 1 221125_WJC_METTL3_EV_vs_WT_F07.11356.11356.4 3.78E-06 14/78 R.FGQGVHHGLSEGWK.E "sp|Q6UWP8|SBSN_HUMAN,sp|Q6UWP8|SBSN_HUMAN" 2 1537.7426 2.23 99040 11356 4 1537.741686 385.4429 Suprabasin OS=Homo sapiens OX=9606 GN=SBSN PE=1 SV=2 6.92 2188.9 - 1.84E+06 - - - -0.6009 - 2.373 0.5 - 77.1 1 2 0 -0.0009 14 0 0 0 2.32E+07 1.04E+07 - - - 3.8922 0.9902 221125_WJC_METTL3_EV_vs_WT_F07.11357.11357.4 0.102 Nov-72 K.DLEEDHAC[160.03]IPIKK.S sp|P13639|EF2_HUMAN 1 1566.7712 0.35 99041 11357 4 1566.768898 392.7001 Elongation factor 2 OS=Homo sapiens OX=9606 GN=EEF2 PE=1 SV=4 4.75 2189 - 936455 - - - -1.4648 - 1.362 0.212 - 66.3 1 2 0 -0.0023 13 0 0 0 2.30E+07 6.65E+07 - - - 1.1852 0.9999 221125_WJC_METTL3_EV_vs_WT_F07.11358.11358.3 2.94E-05 Nov-44 K.LSAMMGAVAEK[136.11]K[136.11].G "sp|Q86U44|MTA70_HUMAN,tr|F5H6D8|F5H6D8_HUMAN,tr|H0YFV6|H0YFV6_HUMAN,tr|B4DTN4|B4DTN4_HUMAN" 4 1250.6698 0.01 99042 11358 3 1250.667426 417.8972 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 8.59 2189.1 - 873192 - - - -1.8702 - 2.259 0.464 - 164 1 2 0 -0.0023 12 0 0 0 6.98E+04 1.36E+07 - - - 5.9713 0.9999 221125_WJC_METTL3_EV_vs_WT_F07.11361.11361.2 2.45E-05 13/32 K.QVSQAQTTVQPSATLQR[166.11].S sp|O00268|TAF4_HUMAN 1 1851.9678 1.67 99045 11361 2 1851.96531 926.9912 Transcription initiation factor TFIID subunit 4 OS=Homo sapiens OX=9606 GN=TAF4 PE=1 SV=2 9.75 2189.5 - 367480 - - - -1.3494 - 2.22 0.596 - 138.3 1 2 0 -0.0025 17 0 0 0 1.40E+07 8.38E+06 - - - 5.403 0.9999 221125_WJC_METTL3_EV_vs_WT_F07.11372.11372.3 6.73E-06 14/48 K.YEVDDIDEEGKER.H sp|Q96ES7|SGF29_HUMAN 1 1595.6951 1.44 99054 11372 3 1595.693574 532.9056 SAGA-associated factor 29 OS=Homo sapiens OX=9606 GN=SGF29 PE=1 SV=1 3.95 2190.8 - 519267 - - - -0.9632 - 2.481 0.525 - 178 1 2 1 -0.0015 13 0 0 0 6.71E+06 4.68E+06 - - - 6.8565 1 221125_WJC_METTL3_EV_vs_WT_F07.11375.11375.2 1.12E-09 14/34 R.TSGADGLVGEDGAADASK[136.11].G sp|Q9ULL5|PRR12_HUMAN 1 1627.7417 2.71 99057 11375 2 1627.739659 814.8781 Proline-rich protein 12 OS=Homo sapiens OX=9606 GN=PRR12 PE=1 SV=3 3.84 2191.2 - 332732 - - - -1.2379 - 2.991 0.634 - 447.8 1 2 0 -0.002 18 0 0 0 9.19E+06 3.40E+06 - - - 6.4167 0.9999 221125_WJC_METTL3_EV_vs_WT_F07.11376.11376.2 1.13E-05 22-Nov K.NQDVSISNVQPK[136.11].T "sp|Q96EV2|RBM33_HUMAN,tr|H0Y3K4|H0Y3K4_HUMAN" 2 1335.6874 0.49 99058 11376 2 1335.687275 668.851 RNA-binding protein 33 OS=Homo sapiens OX=9606 GN=RBM33 PE=1 SV=3 5.84 2191.3 - 273119 - - - -0.0883 - 2.146 0.539 - 542.2 1 2 0 -0.0001 12 0 0 0 3.12E+06 6.38E+06 - - - 5.0312 0.9994 221125_WJC_METTL3_EV_vs_WT_F07.11381.11381.4 0.000196 13/84 K.VGNGHSNEAALILHR[166.11].K sp|Q16706|MA2A1_HUMAN 1 1596.836 1.21 99061 11381 4 1596.834455 400.2163 Alpha-mannosidase 2 OS=Homo sapiens OX=9606 GN=MAN2A1 PE=1 SV=2 6.89 2191.9 - 852326 - - - -0.9719 - 2.357 0.318 - 151.2 1 2 0 -0.0016 15 0 0 0 1.53E+07 1.27E+07 - - - 2.3002 0.9936 221125_WJC_METTL3_EV_vs_WT_F07.11382.11382.3 0.235 Oct-40 R.FK[136.11]EEGVR[166.11]DVLK[136.11].D "sp|P41252|SYIC_HUMAN,tr|A0A804HL54|A0A804HL54_HUMAN,tr|A0A804HKU1|A0A804HKU1_HUMAN,tr|A0A804HK69|A0A804HK69_HUMAN,tr|A0A804HIV9|A0A804HIV9_HUMAN,tr|A0A804HJN6|A0A804HJN6_HUMAN,tr|A0A804HHW9|A0A804HHW9_HUMAN,tr|A0A0A0MSX9|A0A0A0MSX9_HUMAN,tr|J3KR24|J3KR24_HUMAN,tr|A0A804HJ36|A0A804HJ36_HUMAN" 10 1344.7612 0.78 99062 11382 3 1344.761225 449.261 "Isoleucine--tRNA ligase, cytoplasmic OS=Homo sapiens OX=9606 GN=IARS1 PE=1 SV=2" 6.18 2192 - 1.18E+06 - - - 0.0402 - 1.996 0.231 - 98.1 1 2 2 0.0001 11 0 0 0 1.33E+07 1.70E+07 - - - 3.0788 1 221125_WJC_METTL3_EV_vs_WT_F07.11384.11384.3 1.38E-05 13/48 R.ELLKPNASVALHK.H sp|P43686|PRS6B_HUMAN 1 1418.8245 1.44 99064 11384 3 1418.825629 473.9488 26S proteasome regulatory subunit 6B OS=Homo sapiens OX=9606 GN=PSMC4 PE=1 SV=2 8.69 2192.2 - 883187 - - - 0.7612 - 2.521 0.441 - 168.7 1 2 0 0.0011 13 0 0 0 1.55E+07 1.08E+07 - - - 5.9634 0.9999 221125_WJC_METTL3_EV_vs_WT_F07.11385.11385.4 1.09E-05 14/84 R.KPIVPQKEPSPLLEK.K "sp|Q86U86|PB1_HUMAN,tr|E7EVG2|E7EVG2_HUMAN" 2 1702.0029 1.64 99065 11385 4 1702.00337 426.508 Protein polybromo-1 OS=Homo sapiens OX=9606 GN=PBRM1 PE=1 SV=1 8.5 2192.3 - 857087 - - - 0.2714 - 2.857 0.5 - 194.5 1 2 1 0.0005 15 0 0 0 4.70E+07 2.86E+07 - - - 3.9535 1 221125_WJC_METTL3_EV_vs_WT_F07.11389.11389.2 1.82E-10 18/34 R.TSGADGLVGEDGAADASK.G sp|Q9ULL5|PRR12_HUMAN 1 1619.7275 2.71 99069 11389 2 1619.728958 810.871 Proline-rich protein 12 OS=Homo sapiens OX=9606 GN=PRR12 PE=1 SV=3 3.84 2192.7 - 551150 - - - 0.9162 - 3.872 0.722 - 874.3 1 2 0 0.0015 18 0 0 0 9.19E+06 3.40E+06 - - - 7.7015 1 221125_WJC_METTL3_EV_vs_WT_F07.11393.11393.3 6.57E-05 Dec-40 K.QLPHFTSEHIK.R sp|O75643|U520_HUMAN 1 1335.6935 3.28 99071 11393 3 1335.693192 446.2385 U5 small nuclear ribonucleoprotein 200 kDa helicase OS=Homo sapiens OX=9606 GN=SNRNP200 PE=1 SV=2 6.92 2193.3 - 2.01E+06 - - - -0.2568 - 2.268 0.455 - 225 1 2 0 -0.0003 11 0 0 0 8.46E+07 2.58E+07 - - - 5.9391 0.9999 221125_WJC_METTL3_EV_vs_WT_F07.11394.11394.3 4.32E-06 15/56 R.K[136.11]PIVPQK[136.11]EPSPLLEK[136.11].K "sp|Q86U86|PB1_HUMAN,tr|E7EVG2|E7EVG2_HUMAN" 2 1726.0455 1.8 99072 11394 3 1726.046617 576.3558 Protein polybromo-1 OS=Homo sapiens OX=9606 GN=PBRM1 PE=1 SV=1 8.5 2193.4 - 1.20E+06 - - - 0.6425 - 2.962 0.534 - 257.6 1 2 1 0.0011 15 0 0 0 6.13E+07 3.40E+07 - - - 7.3267 0.9998 221125_WJC_METTL3_EV_vs_WT_F07.11395.11395.4 4.03E-05 15/84 R.K[136.11]PIVPQK[136.11]EPSPLLEK[136.11].K "sp|Q86U86|PB1_HUMAN,tr|E7EVG2|E7EVG2_HUMAN" 2 1726.0455 1.64 99073 11395 4 1726.044689 432.5187 Protein polybromo-1 OS=Homo sapiens OX=9606 GN=PBRM1 PE=1 SV=1 8.5 2193.5 - 800445 - - - -0.4745 - 3.192 0.466 - 235.6 1 2 1 -0.0008 15 0 0 0 4.70E+07 2.86E+07 - - - 3.6971 0.9941 221125_WJC_METTL3_EV_vs_WT_F07.11400.11400.3 0.0311 Aug-44 R.QTVEADVNGLRR.V sp|P08779|K1C16_HUMAN 1 1356.711 542.19 99077 11400 3 1356.71045 453.2443 "Keratin, type I cytoskeletal 16 OS=Homo sapiens OX=9606 GN=KRT16 PE=1 SV=4" 6.07 2194.1 - 9.53E+06 - - - -0.3877 - 1.763 0.181 - 115.4 1 2 0 -0.0005 12 0 0 0 1.37E+09 2.53E+06 - - - 2.1295 1 221125_WJC_METTL3_EV_vs_WT_F07.11406.11406.3 1.87E-06 23/56 K.VGNGHSNEAALILHR[166.11].K sp|Q16706|MA2A1_HUMAN 1 1596.836 1.38 99082 11406 3 1596.83443 533.2859 Alpha-mannosidase 2 OS=Homo sapiens OX=9606 GN=MAN2A1 PE=1 SV=2 6.89 2194.8 - 688432 - - - -0.9876 - 3.5 0.538 - 683.6 1 2 0 -0.0016 15 0 0 0 1.29E+07 9.35E+06 - - - 7.8067 0.9996 221125_WJC_METTL3_EV_vs_WT_F07.11411.11411.3 0.00492 15/48 R.K[136.11]NVTLNPDPNEIK[136.11].S sp|Q13907|IDI1_HUMAN 1 1496.817 0.94 99087 11411 3 1496.821449 499.9463 Isopentenyl-diphosphate Delta-isomerase 1 OS=Homo sapiens OX=9606 GN=IDI1 PE=1 SV=2 6.07 2195.4 - 322061 - - - 3.0004 - 2.477 0.381 - 310 1 2 0 0.0045 13 0 0 0 6.40E+06 6.82E+06 - - - 5.2458 0.9892 221125_WJC_METTL3_EV_vs_WT_F07.11413.11413.2 4.67E-05 26-Oct Q.SQTQPVSLANTQPR.G "sp|Q15942|ZYX_HUMAN,tr|H7C3D3|H7C3D3_HUMAN,tr|H0Y2Y8|H0Y2Y8_HUMAN" 3 1525.7849 37.35 99089 11413 2 1525.787191 763.8997 Zyxin OS=Homo sapiens OX=9606 GN=ZYX PE=1 SV=1 9.47 2195.7 - 259461 - - - 1.5218 - 2.27 0.546 - 212.1 1 1 0 0.0023 14 0 0 0 4.02E+06 1.08E+05 - - - 5.1302 0.9999 221125_WJC_METTL3_EV_vs_WT_F07.11418.11418.3 3.73E-08 18/56 R.KPIVPQKEPSPLLEK.K "sp|Q86U86|PB1_HUMAN,tr|E7EVG2|E7EVG2_HUMAN" 2 1702.0029 1.8 99092 11418 3 1702.002955 568.3416 Protein polybromo-1 OS=Homo sapiens OX=9606 GN=PBRM1 PE=1 SV=1 8.5 2196.3 - 3.18E+06 - - - 0.0276 - 2.861 0.6 - 399.4 1 2 1 0 15 0 0 0 6.13E+07 3.40E+07 - - - 7.9723 1 221125_WJC_METTL3_EV_vs_WT_F07.11425.11425.3 2.37E-08 18/52 R.DNAGYC[160.03]ALHEAC[160.03]AR[166.11].G "sp|Q6W2J9|BCOR_HUMAN,tr|H7BZ37|H7BZ37_HUMAN,tr|H7C2V9|H7C2V9_HUMAN,tr|H7C231|H7C231_HUMAN" 4 1616.6699 1.82 99099 11425 3 1617.669376 539.8973 BCL-6 corepressor OS=Homo sapiens OX=9606 GN=BCOR PE=1 SV=1 5.32 2197.1 - 579483 - - - 618.2128 - 3.115 0.718 - 540.8 1 2 0 0.9994 14 0 0 0 3.38E+07 1.85E+07 - - - 9.2877 1 221125_WJC_METTL3_EV_vs_WT_F07.11431.11431.3 6.48E-05 18/52 R.DNAGYC[160.03]ALHEAC[160.03]AR.G "sp|Q6W2J9|BCOR_HUMAN,tr|H7BZ37|H7BZ37_HUMAN,tr|H7C2V9|H7C2V9_HUMAN,tr|H7C231|H7C231_HUMAN" 4 1606.6617 1.82 99103 11431 3 1606.661166 536.5612 BCL-6 corepressor OS=Homo sapiens OX=9606 GN=BCOR PE=1 SV=1 5.32 2197.8 - 1.70E+06 - - - -0.3075 - 3.188 0.634 - 629.2 1 2 0 -0.0005 14 0 0 0 3.38E+07 1.86E+07 - - - 8.6895 1 221125_WJC_METTL3_EV_vs_WT_F07.11434.11434.2 1.16E-15 17/30 K.FNDSEGDDTEETEDYR.Q "sp|Q9NYF8|BCLF1_HUMAN,tr|E9PKI6|E9PKI6_HUMAN,tr|A0A1W2PQ43|A0A1W2PQ43_HUMAN,tr|E9PK91|E9PK91_HUMAN,tr|E9PK09|E9PK09_HUMAN,tr|E9PQN2|E9PQN2_HUMAN" 6 1920.7133 2.98 99106 11434 2 1920.716041 961.3639 Bcl-2-associated transcription factor 1 OS=Homo sapiens OX=9606 GN=BCLAF1 PE=1 SV=2 3.58 2198.1 - 1.01E+06 - - - 1.4062 - 3.665 0.807 - 933.9 1 2 0 0.0027 16 0 0 0 5.51E+07 1.85E+07 - - - 8.1939 0.9882 221125_WJC_METTL3_EV_vs_WT_F07.11436.11436.2 3.71E-06 15/28 K.QTAISQPASGNTFSH.H "sp|Q14157|UBP2L_HUMAN,tr|F8W726|F8W726_HUMAN,tr|Q5VU77|Q5VU77_HUMAN" 3 1544.7219 - 99108 11436 2 1544.721429 773.3682 Ubiquitin-associated protein 2-like OS=Homo sapiens OX=9606 GN=UBAP2L PE=1 SV=2 6.74 2198.3 - 675830 - - - -0.3276 - 2.093 0.438 - 521.9 1 1 0 -0.0005 15 0 0 0 - - - - - 4.0918 1 221125_WJC_METTL3_EV_vs_WT_F07.11440.11440.3 0.263 13/48 R.HEVLLISAEQDKR.A "sp|Q00341|VIGLN_HUMAN,tr|A0A024R4E5|A0A024R4E5_HUMAN,tr|C9JIZ1|C9JIZ1_HUMAN,tr|H7C0A4|H7C0A4_HUMAN,tr|H0Y394|H0Y394_HUMAN" 5 1536.826 1.29 99110 11440 3 1536.826334 513.2826 Vigilin OS=Homo sapiens OX=9606 GN=HDLBP PE=1 SV=2 5.45 2198.8 - 1.93E+06 - - - 0.2134 - 3.055 0.431 - 384.1 1 2 0 0.0003 13 0 0 0 3.50E+07 2.70E+07 - - - 6.373 1 221125_WJC_METTL3_EV_vs_WT_F07.11442.11442.2 2.26E-09 15/30 K.FNDSEGDDTEETEDYR[166.11].Q "sp|Q9NYF8|BCLF1_HUMAN,tr|E9PKI6|E9PKI6_HUMAN,tr|A0A1W2PQ43|A0A1W2PQ43_HUMAN,tr|E9PK91|E9PK91_HUMAN,tr|E9PK09|E9PK09_HUMAN,tr|E9PQN2|E9PQN2_HUMAN" 6 1930.7216 2.97 99112 11442 2 1930.718549 966.3681 Bcl-2-associated transcription factor 1 OS=Homo sapiens OX=9606 GN=BCLAF1 PE=1 SV=2 3.58 2199.1 - 1.00E+06 - - - -1.5854 - 3.144 0.77 - 589.3 1 2 0 -0.0031 16 0 0 0 5.48E+07 1.85E+07 - - - 7.5435 0.9999 221125_WJC_METTL3_EV_vs_WT_F07.11443.11443.2 1.80E-11 16/34 K.SADGSAPAGEGEGVTLQR.N sp|Q01650|LAT1_HUMAN 1 1700.7966 1.45 99113 11443 2 1700.795079 851.4056 Large neutral amino acids transporter small subunit 1 OS=Homo sapiens OX=9606 GN=SLC7A5 PE=1 SV=2 4.14 2199.2 - 782303 - - - -0.8684 - 3.25 0.497 - 494 1 2 0 -0.0015 18 0 0 0 2.25E+07 1.56E+07 - - - 5.6092 1 221125_WJC_METTL3_EV_vs_WT_F07.11445.11445.3 5.78E-12 17/48 K.KPLPDHVSIVEPK.D "sp|P23396|RS3_HUMAN,tr|H0YEU2|H0YEU2_HUMAN,tr|E9PSF4|E9PSF4_HUMAN,tr|E9PL09|E9PL09_HUMAN,tr|E9PPU1|E9PPU1_HUMAN" 5 1457.8242 0.72 99115 11445 3 1457.824503 486.9487 40S ribosomal protein S3 OS=Homo sapiens OX=9606 GN=RPS3 PE=1 SV=2 6.75 2199.5 - 696095 - - - 0.1976 - 3.604 0.604 - 361.1 1 2 0 0.0003 13 0 0 0 8.46E+07 1.18E+08 - - - 8.7499 0.9995 221125_WJC_METTL3_EV_vs_WT_F07.11446.11446.4 0.000876 13/78 K.AVQLK[136.11]PR[166.11]PPQGLVR[166.11].V "sp|Q13724|MOGS_HUMAN,tr|A0A3B3IRK6|A0A3B3IRK6_HUMAN,tr|A0A3B3IRW2|A0A3B3IRW2_HUMAN" 3 1585.9775 0.68 99116 11446 4 1585.976004 397.5016 Mannosyl-oligosaccharide glucosidase OS=Homo sapiens OX=9606 GN=MOGS PE=1 SV=5 12.01 2199.6 - 628335 - - - -0.9244 - 2.044 0.327 - 135.6 1 2 0 -0.0015 14 0 0 0 4.14E+07 6.10E+07 - - - 2.332 0.9832 221125_WJC_METTL3_EV_vs_WT_F07.11447.11447.4 0.0673 Nov-78 K.AVQLKPRPPQGLVR.V "sp|Q13724|MOGS_HUMAN,tr|A0A3B3IRK6|A0A3B3IRK6_HUMAN,tr|A0A3B3IRW2|A0A3B3IRW2_HUMAN" 3 1557.9467 0.6 99117 11447 4 1557.945103 390.494 Mannosyl-oligosaccharide glucosidase OS=Homo sapiens OX=9606 GN=MOGS PE=1 SV=5 12.01 2199.7 - 522951 - - - -1.0443 - 1.674 0.181 - 81.4 1 2 0 -0.0016 14 0 0 0 5.21E+06 8.62E+06 - - - 0.9885 0.9999 221125_WJC_METTL3_EV_vs_WT_F07.11448.11448.3 1.36E-05 Nov-44 R.R[166.11]QQEQQVPILEK[136.11].F "sp|P49327|FAS_HUMAN,tr|A0A0U1RQF0|A0A0U1RQF0_HUMAN" 2 1512.8379 0.89 99118 11448 3 1512.837757 505.2866 Fatty acid synthase OS=Homo sapiens OX=9606 GN=FASN PE=1 SV=3 6.14 2199.9 - 348553 - - - -0.1018 - 2.374 0.368 - 202.4 1 2 0 -0.0002 12 0 0 0 1.45E+07 1.63E+07 - - - 5.0393 0.9994 221125_WJC_METTL3_EV_vs_WT_F07.11449.11449.3 0.00407 Dec-44 R.R[166.11]QQEQQVPILEK[136.11].F "sp|P49327|FAS_HUMAN,tr|A0A0U1RQF0|A0A0U1RQF0_HUMAN" 2 1512.8379 0.89 99119 11449 3 1512.837757 505.2866 Fatty acid synthase OS=Homo sapiens OX=9606 GN=FASN PE=1 SV=3 6.14 2200 - 348553 - - - -0.1018 - 2.217 0.265 - 207.6 1 2 0 -0.0002 12 0 0 0 1.45E+07 1.63E+07 - - - 3.7013 0.9978 221125_WJC_METTL3_EV_vs_WT_F07.11452.11452.3 0.00308 Nov-40 K.QLPHFTSEHIK[136.11].R sp|O75643|U520_HUMAN 1 1343.7077 2.37 99121 11452 3 1343.706372 448.9099 U5 small nuclear ribonucleoprotein 200 kDa helicase OS=Homo sapiens OX=9606 GN=SNRNP200 PE=1 SV=2 6.92 2200.5 - 585124 - - - -1.0144 - 2.157 0.184 - 179 1 2 0 -0.0014 11 0 0 0 3.46E+07 1.46E+07 - - - 2.7748 0.9989 221125_WJC_METTL3_EV_vs_WT_F07.11453.11453.3 0.11 13/44 K.HFVGMLPEKDC[160.03]R.Y "sp|P60981|DEST_HUMAN,tr|F6RFD5|F6RFD5_HUMAN" 2 1487.7013 16.57 99122 11453 3 1487.699133 496.9077 Destrin OS=Homo sapiens OX=9606 GN=DSTN PE=1 SV=3 6.74 2200.6 - 403195 - - - -1.4835 - 2.427 0.324 - 261.7 1 2 1 -0.0022 12 0 0 0 2.51E+07 1.51E+06 - - - 4.6093 1 221125_WJC_METTL3_EV_vs_WT_F07.11455.11455.3 1.51E-08 19/48 K.K[136.11]PLPDHVSIVEPK[136.11].D "sp|P23396|RS3_HUMAN,tr|H0YEU2|H0YEU2_HUMAN,tr|E9PSF4|E9PSF4_HUMAN,tr|E9PL09|E9PL09_HUMAN,tr|E9PPU1|E9PPU1_HUMAN" 5 1473.8526 0.72 99124 11455 3 1473.851662 492.2915 40S ribosomal protein S3 OS=Homo sapiens OX=9606 GN=RPS3 PE=1 SV=2 6.75 2200.8 - 1.47E+06 - - - -0.6466 - 3.475 0.537 - 515.5 1 2 0 -0.001 13 0 0 0 8.46E+07 1.18E+08 - - - 7.9039 1 221125_WJC_METTL3_EV_vs_WT_F07.11456.11456.3 4.93E-07 13/44 R.SQPVYIQYSNHR[166.11].E "sp|O95758|PTBP3_HUMAN,tr|X6R242|X6R242_HUMAN" 2 1500.7349 1.14 99125 11456 3 1500.735177 501.2522 Polypyrimidine tract-binding protein 3 OS=Homo sapiens OX=9606 GN=PTBP3 PE=1 SV=2 8.33 2200.9 - 1.14E+06 - - - 0.1872 - 2.44 0.543 - 238.8 1 2 0 0.0003 12 0 0 0 7.31E+07 6.41E+07 - - - 7.0663 0.9999 221125_WJC_METTL3_EV_vs_WT_F07.11458.11458.3 8.91E-05 Nov-40 K.TSLMNQYVNKK.F "sp|P51149|RAB7A_HUMAN,tr|C9J592|C9J592_HUMAN,tr|C9J4V0|C9J4V0_HUMAN,tr|C9J7D1|C9J7D1_HUMAN,tr|A0A6Q8PH84|A0A6Q8PH84_HUMAN,tr|C9J8S3|C9J8S3_HUMAN,tr|C9IZZ0|C9IZZ0_HUMAN,tr|C9J4S4|C9J4S4_HUMAN,tr|A0A6Q8PG52|A0A6Q8PG52_HUMAN" 9 1324.6809 0.5 99127 11458 3 1324.679835 442.5676 Ras-related protein Rab-7a OS=Homo sapiens OX=9606 GN=RAB7A PE=1 SV=1 9.7 2201.2 - 614204 - - - -0.8198 - 2.462 0.37 - 226.7 1 2 0 -0.0011 11 0 0 0 9.51E+06 1.90E+07 - - - 5.2243 0.9999 221125_WJC_METTL3_EV_vs_WT_F07.11465.11465.3 8.41E-07 13/52 R.AELYK[136.11]EPTNEELNR[166.11].L "sp|Q9H6R4|NOL6_HUMAN,tr|A0A0A0MRW6|A0A0A0MRW6_HUMAN" 2 1722.8543 1.07 99132 11465 3 1722.85494 575.2921 Nucleolar protein 6 OS=Homo sapiens OX=9606 GN=NOL6 PE=1 SV=2 4.49 2202 - 2.30E+06 - - - 0.343 - 2.779 0.533 - 209.2 1 2 1 0.0006 14 0 0 0 2.04E+07 1.90E+07 - - - 7.1985 1 221125_WJC_METTL3_EV_vs_WT_F07.11466.11466.3 1.21E-06 Dec-60 K.FNDSEGDDTEETEDYR.Q "sp|Q9NYF8|BCLF1_HUMAN,tr|E9PKI6|E9PKI6_HUMAN,tr|A0A1W2PQ43|A0A1W2PQ43_HUMAN,tr|E9PK91|E9PK91_HUMAN,tr|E9PK09|E9PK09_HUMAN,tr|E9PQN2|E9PQN2_HUMAN" 6 1920.7133 2.34 99133 11466 3 1920.707379 641.2451 Bcl-2-associated transcription factor 1 OS=Homo sapiens OX=9606 GN=BCLAF1 PE=1 SV=2 3.58 2202.1 - 1.04E+06 - - - -3.1035 - 2.325 0.775 - 152.9 1 2 0 -0.006 16 0 0 0 7.11E+06 3.04E+06 - - - 9.3437 0.9999 221125_WJC_METTL3_EV_vs_WT_F07.11467.11467.2 8.36E-12 17/34 K.SADGSAPAGEGEGVTLQR[166.11].N sp|Q01650|LAT1_HUMAN 1 1710.8048 1.45 99134 11467 2 1710.804332 856.4097 Large neutral amino acids transporter small subunit 1 OS=Homo sapiens OX=9606 GN=SLC7A5 PE=1 SV=2 4.14 2202.2 - 883036 - - - -0.2888 - 3.072 0.517 - 620.1 1 2 0 -0.0005 18 0 0 0 2.25E+07 1.56E+07 - - - 5.6187 0.9997 221125_WJC_METTL3_EV_vs_WT_F07.11469.11469.3 0.000506 Dec-44 R.SQYEALVETNRR.E "sp|Q15323|K1H1_HUMAN,sp|O76009|KT33A_HUMAN,tr|A0A140TA62|A0A140TA62_HUMAN,tr|A0A140TA69|A0A140TA69_HUMAN" 4 1464.7321 14.71 99136 11469 3 1464.733149 489.2513 "Keratin, type I cuticular Ha1 OS=Homo sapiens OX=9606 GN=KRT31 PE=1 SV=3" 5.86 2202.5 - 591909 - - - 0.7128 - 1.901 0.34 - 249.9 1 2 0 0.001 12 0 0 0 5.42E+06 3.68E+05 - - - 4.111 0.9996 221125_WJC_METTL3_EV_vs_WT_F07.11471.11471.3 0.00023 Oct-84 K.LVSTATTAPPSTAPSGPGSVQK[136.11].Y "sp|P49848|TAF6_HUMAN,tr|J3KR72|J3KR72_HUMAN" 2 2061.0833 1.93 99138 11471 3 2061.085126 688.0351 Transcription initiation factor TFIID subunit 6 OS=Homo sapiens OX=9606 GN=TAF6 PE=1 SV=1 8.75 2202.8 - 333898 - - - 0.8622 - 1.942 0.356 - 54.4 1 2 0 0.0018 22 0 0 0 7.41E+06 3.84E+06 - - - 4.0821 1 221125_WJC_METTL3_EV_vs_WT_F07.11472.11472.2 9.29E-08 26-Oct R.DNAGYC[160.03]ALHEAC[160.03]AR.G "sp|Q6W2J9|BCOR_HUMAN,tr|H7BZ37|H7BZ37_HUMAN,tr|H7C2V9|H7C2V9_HUMAN,tr|H7C231|H7C231_HUMAN" 4 1606.6617 -1 99139 11472 2 1606.662798 804.3381 BCL-6 corepressor OS=Homo sapiens OX=9606 GN=BCOR PE=1 SV=1 5.32 2202.9 - 259341 - - - 0.7083 - 2.481 0.624 - 71.9 1 2 0 0.0011 14 0 0 0 0.00E+00 0.00E+00 - - - 5.9297 0.9917 221125_WJC_METTL3_EV_vs_WT_F07.11474.11474.3 0.000173 Nov-52 R.MEEKDYTVTQVPPK.H "sp|Q8N5Z5|KCD17_HUMAN,tr|A0A087WX35|A0A087WX35_HUMAN,tr|H0Y731|H0Y731_HUMAN" 3 1663.8127 0.69 99140 11474 3 1663.820384 555.6115 BTB\POZ domain-containing protein KCTD17 OS=Homo sapiens OX=9606 GN=KCTD17 PE=1 SV=3 4.68 2203.1 - 668370 - - - 4.6039 - 2.029 0.397 - 131.8 1 2 1 0.0077 14 0 0 0 1.11E+07 1.62E+07 - - - 4.8444 0.9999 221125_WJC_METTL3_EV_vs_WT_F07.11476.11476.3 0.00892 15/52 R.AELYKEPTNEELNR.L "sp|Q9H6R4|NOL6_HUMAN,tr|A0A0A0MRW6|A0A0A0MRW6_HUMAN" 2 1704.8319 1.07 99141 11476 3 1704.830162 569.2846 Nucleolar protein 6 OS=Homo sapiens OX=9606 GN=NOL6 PE=1 SV=2 4.49 2203.3 - 2.34E+06 - - - -1.0071 - 2.951 0.472 - 261.4 1 2 1 -0.0017 14 0 0 0 2.04E+07 1.90E+07 - - - 6.6777 1 221125_WJC_METTL3_EV_vs_WT_F07.11477.11477.3 1.25E-06 17/76 R.GRPAGGNGSGLC[160.03]GGGVLGAR.S sp|Q5JSZ5|PRC2B_HUMAN 1 1768.8751 0.86 99142 11477 3 1768.875193 590.6323 Protein PRRC2B OS=Homo sapiens OX=9606 GN=PRRC2B PE=1 SV=2 10.35 2203.4 - 1.52E+06 - - - 0.0537 - 3.079 0.526 - 293 1 2 0 0.0001 20 0 0 0 1.11E+07 1.29E+07 - - - 7.1327 1 221125_WJC_METTL3_EV_vs_WT_F07.11478.11478.3 3.86E-07 14/48 R.HYTFASGSPDNIK[136.11].Q "sp|O43660|PLRG1_HUMAN,tr|H0YAA2|H0YAA2_HUMAN" 2 1443.6874 1.35 99143 11478 3 1443.687409 482.2364 Pleiotropic regulator 1 OS=Homo sapiens OX=9606 GN=PLRG1 PE=1 SV=1 6.74 2203.5 - 2.05E+06 - - - 0.0111 - 2.649 0.54 - 381.6 1 2 0 0 13 0 0 0 2.84E+07 2.10E+07 - - - 7.2018 1 221125_WJC_METTL3_EV_vs_WT_F07.11479.11479.3 0.0036 14/44 R.DSLTGSSDLYKR.T "sp|Q14671|PUM1_HUMAN,tr|Q5T1Z8|Q5T1Z8_HUMAN,tr|H0YDK8|H0YDK8_HUMAN,tr|Q5T1Z4|Q5T1Z4_HUMAN,tr|E9PR38|E9PR38_HUMAN" 5 1340.6572 3.67 99144 11479 3 1340.656333 447.893 Pumilio homolog 1 OS=Homo sapiens OX=9606 GN=PUM1 PE=1 SV=3 5.96 2203.6 - 915915 - - - -0.6534 - 3.143 0.388 - 550 1 2 0 -0.0009 12 0 0 0 8.38E+06 2.28E+06 - - - 6.0398 1 221125_WJC_METTL3_EV_vs_WT_F07.11480.11480.2 6.08E-11 18/24 R.HYTFASGSPDNIK[136.11].Q "sp|O43660|PLRG1_HUMAN,tr|H0YAA2|H0YAA2_HUMAN" 2 1443.6874 0.95 99145 11480 2 1443.685946 722.851 Pleiotropic regulator 1 OS=Homo sapiens OX=9606 GN=PLRG1 PE=1 SV=1 6.74 2203.7 - 676549 - - - -1.0023 - 3.458 0.624 - 841.8 1 2 0 -0.0014 13 0 0 0 9.02E+06 9.46E+06 - - - 6.8337 1 221125_WJC_METTL3_EV_vs_WT_F07.11482.11482.2 3.28E-10 13/28 R.NGPSSSPFSSPASSR.S "sp|Q96HA1|P121A_HUMAN,sp|A6NF01|P121B_HUMAN,sp|A8CG34|P121C_HUMAN,tr|C9JFL1|C9JFL1_HUMAN" 4 1463.6641 1.59 99147 11482 2 1463.66201 732.8393 Nuclear envelope pore membrane protein POM 121 OS=Homo sapiens OX=9606 GN=POM121 PE=1 SV=2 9.75 2203.9 - 533427 - - - -1.4177 - 2.755 0.569 - 354.1 1 2 0 -0.0021 15 0 0 0 2.82E+07 1.77E+07 - - - 5.7345 0.9998 221125_WJC_METTL3_EV_vs_WT_F07.11483.11483.3 0.00294 15/84 K.LVSTATTAPPSTAPSGPGSVQK.Y "sp|P49848|TAF6_HUMAN,tr|J3KR72|J3KR72_HUMAN" 2 2053.0691 1.93 99148 11483 3 2053.068325 685.3637 Transcription initiation factor TFIID subunit 6 OS=Homo sapiens OX=9606 GN=TAF6 PE=1 SV=1 8.75 2204.1 - 477957 - - - -0.4014 - 2.585 0.355 - 91.5 1 2 0 -0.0008 22 0 0 0 7.41E+06 3.84E+06 - - - 4.7493 0.9998 221125_WJC_METTL3_EV_vs_WT_F07.11485.11485.2 5.21E-06 22-Oct R.SQPVYIQYSNHR[166.11].E "sp|O95758|PTBP3_HUMAN,tr|X6R242|X6R242_HUMAN" 2 1500.7349 0.98 99150 11485 2 1500.732128 751.3747 Polypyrimidine tract-binding protein 3 OS=Homo sapiens OX=9606 GN=PTBP3 PE=1 SV=2 8.33 2204.3 - 281672 - - - -1.8444 - 2.02 0.551 - 356.2 1 2 0 -0.0028 12 0 0 0 4.01E+06 4.08E+06 - - - 4.9598 0.9944 221125_WJC_METTL3_EV_vs_WT_F07.11486.11486.2 6.90E-08 18-Oct Q.PVYIQYSNHR.E "sp|O95758|PTBP3_HUMAN,tr|X6R242|X6R242_HUMAN" 2 1275.636 1.22 99151 11486 2 1275.636458 638.8253 Polypyrimidine tract-binding protein 3 OS=Homo sapiens OX=9606 GN=PTBP3 PE=1 SV=2 9.01 2204.5 - 248260 - - - 0.3434 - 2.135 0.584 - 442 1 1 0 0.0004 10 0 0 0 3.99E+06 3.26E+06 - - - 5.4714 1 221125_WJC_METTL3_EV_vs_WT_F07.11490.11490.2 2.35E-11 18/32 K.VPEPC[160.03]PSTVTPAPAQQK.T sp|P35321|SPR1A_HUMAN 1 1805.8982 999 99154 11490 2 1805.898131 903.9564 Cornifin-A OS=Homo sapiens OX=9606 GN=SPRR1A PE=1 SV=2 5.97 2204.9 - 1.37E+06 - - - -0.0299 - 3.106 0.737 - 859.6 1 2 0 -0.0001 17 0 0 0 6.44E+07 0.00E+00 - - - 7.2708 0.9998 221125_WJC_METTL3_EV_vs_WT_F07.11493.11493.3 9.87E-05 Nov-40 R.NKYETEINITK.T sp|P15924|DESP_HUMAN 1 1351.6983 12.37 99157 11493 3 1351.698284 451.5734 Desmoplakin OS=Homo sapiens OX=9606 GN=DSP PE=1 SV=3 6.14 2205.2 - 1.09E+06 - - - -0.0459 - 2.395 0.431 - 256.9 1 2 1 -0.0001 11 0 0 0 1.50E+08 1.21E+07 - - - 5.8263 0.9955 221125_WJC_METTL3_EV_vs_WT_F07.11495.11495.3 0.00653 Dec-40 K.QDSSKELEELR.A "sp|Q15020|SART3_HUMAN,tr|A0A499FI31|A0A499FI31_HUMAN" 2 1332.6521 4.7 99159 11495 3 1332.649568 445.2247 Squamous cell carcinoma antigen recognized by T-cells 3 OS=Homo sapiens OX=9606 GN=SART3 PE=1 SV=1 4.41 2205.4 - 866589 - - - -1.918 - 1.943 0.295 - 196.6 1 2 1 -0.0026 11 0 0 0 1.21E+07 2.58E+06 - - - 3.7152 0.9995 221125_WJC_METTL3_EV_vs_WT_F07.11496.11496.2 0.00199 12-Jul K.DNNLLGR[166.11].F "sp|P0DMV8|HS71A_HUMAN,sp|P34931|HS71L_HUMAN,sp|P0DMV9|HS71B_HUMAN,sp|P17066|HSP76_HUMAN,tr|Q53FA3|Q53FA3_HUMAN,tr|V9GZ37|V9GZ37_HUMAN,tr|A0A0G2JIW1|A0A0G2JIW1_HUMAN" 7 810.4223 0.32 99160 11496 2 810.420922 406.2184 Heat shock 70 kDa protein 1A OS=Homo sapiens OX=9606 GN=HSPA1A PE=1 SV=1 5.84 2205.5 - 655080 - - - -1.7448 - 1.393 0.475 - 308.5 1 2 0 -0.0014 7 0 0 0 2.11E+06 6.61E+06 - - - 3.5992 0.9728 221125_WJC_METTL3_EV_vs_WT_F07.11498.11498.3 0.0847 Jul-60 R.K[136.11]PSVGVPPPASPSYPR[166.11].A sp|Q9P206|K1522_HUMAN 1 1652.9005 0.07 99162 11498 3 1652.901947 551.9741 Uncharacterized protein KIAA1522 OS=Homo sapiens OX=9606 GN=KIAA1522 PE=1 SV=2 9.99 2205.8 - 461367 - - - 0.8688 - 1.415 0.197 - 39.3 7 2 0 0.0014 16 0 0 0 8.17E+05 1.16E+07 - - - 1.2355 0.9998 221125_WJC_METTL3_EV_vs_WT_F07.11499.11499.2 8.19E-05 28-Oct R.NGPSSSPFSSPASSR[166.11].S "sp|Q96HA1|P121A_HUMAN,sp|A6NF01|P121B_HUMAN,sp|A8CG34|P121C_HUMAN,tr|C9JFL1|C9JFL1_HUMAN" 4 1473.6724 1.61 99163 11499 2 1473.669256 737.8435 Nuclear envelope pore membrane protein POM 121 OS=Homo sapiens OX=9606 GN=POM121 PE=1 SV=2 9.75 2205.9 - 406081 - - - -2.1029 - 2.228 0.568 - 208.6 1 2 0 -0.0031 15 0 0 0 2.82E+07 1.75E+07 - - - 5.2048 0.9994 221125_WJC_METTL3_EV_vs_WT_F07.11500.11500.2 2.10E-06 22-Oct R.SQPVYIQYSNHR.E "sp|O95758|PTBP3_HUMAN,tr|X6R242|X6R242_HUMAN" 2 1490.7266 0.98 99164 11500 2 1490.721705 746.3706 Polypyrimidine tract-binding protein 3 OS=Homo sapiens OX=9606 GN=PTBP3 PE=1 SV=2 8.33 2206 - 372733 - - - -3.3011 - 2.018 0.555 - 446.9 1 2 0 -0.0049 12 0 0 0 4.01E+06 4.08E+06 - - - 4.986 1 221125_WJC_METTL3_EV_vs_WT_F07.11502.11502.3 1.50E-10 15/48 R.HYTFASGSPDNIK.Q "sp|O43660|PLRG1_HUMAN,tr|H0YAA2|H0YAA2_HUMAN" 2 1435.6732 1.42 99165 11502 3 1435.672915 479.565 Pleiotropic regulator 1 OS=Homo sapiens OX=9606 GN=PLRG1 PE=1 SV=1 6.74 2206.2 - 2.38E+06 - - - -0.1936 - 2.65 0.607 - 448.8 1 2 0 -0.0003 13 0 0 0 2.55E+07 1.79E+07 - - - 7.9497 0.9999 221125_WJC_METTL3_EV_vs_WT_F07.11503.11503.3 5.43E-06 14/64 K.VPEPC[160.03]PSTVTPAPAQQK.T sp|P35321|SPR1A_HUMAN 1 1805.8982 999 99166 11503 3 1805.901211 602.9733 Cornifin-A OS=Homo sapiens OX=9606 GN=SPRR1A PE=1 SV=2 5.97 2206.3 - 1.51E+06 - - - 1.6756 - 2.379 0.479 - 179 1 2 0 0.003 17 0 0 0 6.65E+07 0.00E+00 - - - 6.069 0.9988 221125_WJC_METTL3_EV_vs_WT_F07.11505.11505.2 7.47E-05 14/20 R.NKYETEINITK.T sp|P15924|DESP_HUMAN 1 1351.6983 66.76 99168 11505 2 1351.69918 676.8564 Desmoplakin OS=Homo sapiens OX=9606 GN=DSP PE=1 SV=3 6.14 2206.5 - 941888 - - - 0.617 - 2.525 0.52 - 646.2 1 2 1 0.0008 11 0 0 0 3.39E+07 5.08E+05 - - - 5.3872 0.9999 221125_WJC_METTL3_EV_vs_WT_F07.11507.11507.3 0.000289 13/36 R.HHSLALTSFK[136.11].R "sp|Q9BSV6|SEN34_HUMAN,tr|A0A590UJ73|A0A590UJ73_HUMAN,tr|E7EQB3|E7EQB3_HUMAN,tr|A0A0G2JNK5|A0A0G2JNK5_HUMAN,tr|A0A0G2JNL0|A0A0G2JNL0_HUMAN,tr|A0A590UJW4|A0A590UJW4_HUMAN,tr|B0V3J0|B0V3J0_HUMAN" 7 1147.6229 1.78 99170 11507 3 1147.622746 383.5483 tRNA-splicing endonuclease subunit Sen34 OS=Homo sapiens OX=9606 GN=TSEN34 PE=1 SV=1 8.76 2206.8 - 394665 - - - -0.1717 - 2.225 0.406 - 229.8 1 2 0 -0.0002 10 0 0 0 3.13E+07 1.76E+07 - - - 5.4021 1 221125_WJC_METTL3_EV_vs_WT_F07.11509.11509.2 9.10E-09 17/24 R.HYTFASGSPDNIK.Q "sp|O43660|PLRG1_HUMAN,tr|H0YAA2|H0YAA2_HUMAN" 2 1435.6732 0.95 99171 11509 2 1435.671741 718.8439 Pleiotropic regulator 1 OS=Homo sapiens OX=9606 GN=PLRG1 PE=1 SV=1 6.74 2207 - 631779 - - - -1.0114 - 3.17 0.639 - 832.9 1 2 0 -0.0015 13 0 0 0 9.02E+06 9.46E+06 - - - 6.7213 0.9999 221125_WJC_METTL3_EV_vs_WT_F07.11522.11522.3 5.57E-06 13/48 R.NVMEEGK[136.11]DFQPSR[166.11].S "sp|P35606|COPB2_HUMAN,tr|H0Y938|H0Y938_HUMAN,tr|A0A7I2V258|A0A7I2V258_HUMAN,tr|H0YAC7|H0YAC7_HUMAN" 4 1553.7263 0.53 99181 11522 3 1553.724507 518.916 Coatomer subunit beta' OS=Homo sapiens OX=9606 GN=COPB2 PE=1 SV=2 4.68 2208.3 - 1.04E+06 - - - -1.1617 - 2.542 0.56 - 252.2 1 2 1 -0.0018 13 0 0 0 1.86E+07 3.49E+07 - - - 7.3124 0.9999 221125_WJC_METTL3_EV_vs_WT_F07.11523.11523.3 1.50E-05 15/36 R.HHSLALTSFK.R "sp|Q9BSV6|SEN34_HUMAN,tr|A0A590UJ73|A0A590UJ73_HUMAN,tr|E7EQB3|E7EQB3_HUMAN,tr|A0A0G2JNK5|A0A0G2JNK5_HUMAN,tr|A0A0G2JNL0|A0A0G2JNL0_HUMAN,tr|A0A590UJW4|A0A590UJW4_HUMAN,tr|B0V3J0|B0V3J0_HUMAN" 7 1139.6087 1.74 99182 11523 3 1139.608582 380.8769 tRNA-splicing endonuclease subunit Sen34 OS=Homo sapiens OX=9606 GN=TSEN34 PE=1 SV=1 8.76 2208.5 - 946747 - - - -0.1413 - 2.283 0.433 - 366.3 1 2 0 -0.0002 10 0 0 0 3.15E+07 1.82E+07 - - - 5.7783 0.9996 221125_WJC_METTL3_EV_vs_WT_F07.11525.11525.4 0.00281 17/84 R.LTGVSISQVNHKPLR.T "sp|O75955|FLOT1_HUMAN,tr|A0A140T9W4|A0A140T9W4_HUMAN,tr|A0A140T9R1|A0A140T9R1_HUMAN,tr|A0A140T974|A0A140T974_HUMAN" 4 1647.942 1.53 99184 11525 4 1647.941529 412.9928 Flotillin-1 OS=Homo sapiens OX=9606 GN=FLOT1 PE=1 SV=3 11 2208.7 - 567453 - - - -0.3095 - 2.685 0.328 - 177.7 1 2 0 -0.0005 15 0 0 0 3.69E+07 2.41E+07 - - - 2.4342 0.9976 221125_WJC_METTL3_EV_vs_WT_F07.11526.11526.3 0.103 Sep-36 K.DQHSFELDEK.A "sp|Q6DD88|ATLA3_HUMAN,tr|F5GWF8|F5GWF8_HUMAN,tr|F5H6I7|F5H6I7_HUMAN" 3 1246.5466 1.27 99185 11526 3 1246.545008 416.5228 Atlastin-3 OS=Homo sapiens OX=9606 GN=ATL3 PE=1 SV=1 4.31 2208.8 - 516964 - - - -1.2739 - 1.8 0.229 - 141.8 1 2 0 -0.0016 10 0 0 0 1.13E+07 8.93E+06 - - - 2.8093 1 221125_WJC_METTL3_EV_vs_WT_F07.11532.11532.3 0.0337 17/40 K.K[136.11]EDLYLK[136.11]PIQR[166.11].T sp|P13639|EF2_HUMAN 1 1427.8347 0.44 99189 11532 3 1427.835182 476.9522 Elongation factor 2 OS=Homo sapiens OX=9606 GN=EEF2 PE=1 SV=4 8.5 2209.4 - 2.41E+06 - - - 0.3586 - 2.915 0.489 - 465.7 1 2 0 0.0005 11 0 0 0 3.48E+07 7.84E+07 - - - 7.031 0.9986 221125_WJC_METTL3_EV_vs_WT_F07.11533.11533.4 5.15E-05 13/84 K.LGETYK[136.11]DHENIVIAK[136.11].M "sp|P07237|PDIA1_HUMAN,tr|A0A7P0TA97|A0A7P0TA97_HUMAN,tr|A0A7P0T8C0|A0A7P0T8C0_HUMAN,tr|H7BZ94|H7BZ94_HUMAN,tr|B3KTQ9|B3KTQ9_HUMAN,tr|A0A7P0TA71|A0A7P0TA71_HUMAN,tr|I3L4M2|I3L4M2_HUMAN,tr|A0A7P0T9K9|A0A7P0T9K9_HUMAN,tr|H0Y3Z3|H0Y3Z3_HUMAN,tr|A0A7P0TA35|A0A7P0TA35_HUMAN,tr|A0A7P0TB26|A0A7P0TB26_HUMAN,tr|A0A7P0T9U6|A0A7P0T9U6_HUMAN,tr|I3L0S0|I3L0S0_HUMAN,tr|I3L3P5|I3L3P5_HUMAN,tr|A0A7P0T8J3|A0A7P0T8J3_HUMAN,tr|A0A7P0T8X1|A0A7P0T8X1_HUMAN" 16 1744.9331 1.32 99190 11533 4 1744.93115 437.2405 Protein disulfide-isomerase OS=Homo sapiens OX=9606 GN=P4HB PE=1 SV=3 5.45 2209.5 - 1.18E+06 - - - -1.0889 - 2.533 0.34 - 110.6 1 2 1 -0.0019 15 0 0 0 1.38E+08 1.04E+08 - - - 2.5174 0.9999 221125_WJC_METTL3_EV_vs_WT_F07.11534.11534.3 1.17E-05 14/52 R.YANNSNYKNDVMIR.K "sp|Q96A72|MGN2_HUMAN,sp|P61326|MGN_HUMAN,tr|F5H6N1|F5H6N1_HUMAN" 3 1700.7941 0.49 99191 11534 3 1700.795441 567.9386 Protein mago nashi homolog 2 OS=Homo sapiens OX=9606 GN=MAGOHB PE=1 SV=1 8.5 2209.6 - 1.10E+06 - - - 0.8155 - 2.57 0.588 - 134.8 1 2 1 0.0014 14 0 0 0 2.12E+07 4.35E+07 - - - 7.6037 0.9994 221125_WJC_METTL3_EV_vs_WT_F07.11535.11535.4 0.00112 16/84 K.LGETYKDHENIVIAK.M "sp|P07237|PDIA1_HUMAN,tr|A0A7P0TA97|A0A7P0TA97_HUMAN,tr|A0A7P0T8C0|A0A7P0T8C0_HUMAN,tr|H7BZ94|H7BZ94_HUMAN,tr|B3KTQ9|B3KTQ9_HUMAN,tr|A0A7P0TA71|A0A7P0TA71_HUMAN,tr|I3L4M2|I3L4M2_HUMAN,tr|A0A7P0T9K9|A0A7P0T9K9_HUMAN,tr|H0Y3Z3|H0Y3Z3_HUMAN,tr|A0A7P0TA35|A0A7P0TA35_HUMAN,tr|A0A7P0TB26|A0A7P0TB26_HUMAN,tr|A0A7P0T9U6|A0A7P0T9U6_HUMAN,tr|I3L0S0|I3L0S0_HUMAN,tr|I3L3P5|I3L3P5_HUMAN,tr|A0A7P0T8J3|A0A7P0T8J3_HUMAN,tr|A0A7P0T8X1|A0A7P0T8X1_HUMAN" 16 1728.9046 1.3 99192 11535 4 1728.906071 433.2334 Protein disulfide-isomerase OS=Homo sapiens OX=9606 GN=P4HB PE=1 SV=3 5.45 2209.7 - 1.04E+06 - - - 0.8219 - 2.636 0.387 - 219.8 1 2 1 0.0014 15 0 0 0 1.39E+08 1.07E+08 - - - 2.9409 0.9999 221125_WJC_METTL3_EV_vs_WT_F07.11536.11536.3 2.91E-06 20/56 K.LGETYKDHENIVIAK.M "sp|P07237|PDIA1_HUMAN,tr|A0A7P0TA97|A0A7P0TA97_HUMAN,tr|A0A7P0T8C0|A0A7P0T8C0_HUMAN,tr|H7BZ94|H7BZ94_HUMAN,tr|B3KTQ9|B3KTQ9_HUMAN,tr|A0A7P0TA71|A0A7P0TA71_HUMAN,tr|I3L4M2|I3L4M2_HUMAN,tr|A0A7P0T9K9|A0A7P0T9K9_HUMAN,tr|H0Y3Z3|H0Y3Z3_HUMAN,tr|A0A7P0TA35|A0A7P0TA35_HUMAN,tr|A0A7P0TB26|A0A7P0TB26_HUMAN,tr|A0A7P0T9U6|A0A7P0T9U6_HUMAN,tr|I3L0S0|I3L0S0_HUMAN,tr|I3L3P5|I3L3P5_HUMAN,tr|A0A7P0T8J3|A0A7P0T8J3_HUMAN,tr|A0A7P0T8X1|A0A7P0T8X1_HUMAN" 16 1728.9046 1.4 99193 11536 3 1728.907924 577.3088 Protein disulfide-isomerase OS=Homo sapiens OX=9606 GN=P4HB PE=1 SV=3 5.45 2209.9 - 870920 - - - 1.8937 - 3.732 0.509 - 454.2 1 2 1 0.0033 15 0 0 0 9.66E+07 6.90E+07 - - - 7.6503 1 221125_WJC_METTL3_EV_vs_WT_F07.11538.11538.3 1.06E-05 21/56 K.LGETYK[136.11]DHENIVIAK[136.11].M "sp|P07237|PDIA1_HUMAN,tr|A0A7P0TA97|A0A7P0TA97_HUMAN,tr|A0A7P0T8C0|A0A7P0T8C0_HUMAN,tr|H7BZ94|H7BZ94_HUMAN,tr|B3KTQ9|B3KTQ9_HUMAN,tr|A0A7P0TA71|A0A7P0TA71_HUMAN,tr|I3L4M2|I3L4M2_HUMAN,tr|A0A7P0T9K9|A0A7P0T9K9_HUMAN,tr|H0Y3Z3|H0Y3Z3_HUMAN,tr|A0A7P0TA35|A0A7P0TA35_HUMAN,tr|A0A7P0TB26|A0A7P0TB26_HUMAN,tr|A0A7P0T9U6|A0A7P0T9U6_HUMAN,tr|I3L0S0|I3L0S0_HUMAN,tr|I3L3P5|I3L3P5_HUMAN,tr|A0A7P0T8J3|A0A7P0T8J3_HUMAN,tr|A0A7P0T8X1|A0A7P0T8X1_HUMAN" 16 1744.9331 1.44 99195 11538 3 1744.934129 582.6516 Protein disulfide-isomerase OS=Homo sapiens OX=9606 GN=P4HB PE=1 SV=3 5.45 2210.1 - 685398 - - - 0.6184 - 3.885 0.547 - 673.8 1 2 1 0.0011 15 0 0 0 1.00E+08 6.96E+07 - - - 8.1794 0.9998 221125_WJC_METTL3_EV_vs_WT_F07.11542.11542.3 0.000421 Nov-52 K.AVQLK[136.11]PR[166.11]PPQGLVR[166.11].V "sp|Q13724|MOGS_HUMAN,tr|A0A3B3IRK6|A0A3B3IRK6_HUMAN,tr|A0A3B3IRW2|A0A3B3IRW2_HUMAN" 3 1585.9775 0.76 99197 11542 3 1585.977951 529.6664 Mannosyl-oligosaccharide glucosidase OS=Homo sapiens OX=9606 GN=MOGS PE=1 SV=5 12.01 2210.7 - 1.59E+06 - - - 0.3033 - 2.178 0.358 - 199.3 1 2 0 0.0005 14 0 0 0 2.79E+07 3.66E+07 - - - 4.5999 0.9999 221125_WJC_METTL3_EV_vs_WT_F07.11547.11547.3 0.000103 Nov-48 K.VADWTGATYQDK[136.11]R[166.11].Y "sp|O15371|EIF3D_HUMAN,tr|B0QYA8|B0QYA8_HUMAN,tr|B0QYA6|B0QYA6_HUMAN,tr|B0QYA5|B0QYA5_HUMAN" 4 1527.7437 1.07 99202 11547 3 1527.742131 510.2552 Eukaryotic translation initiation factor 3 subunit D OS=Homo sapiens OX=9606 GN=EIF3D PE=1 SV=1 5.93 2211 - 695912 - - - -1.0113 - 2.29 0.39 - 224.5 1 2 0 -0.0015 13 0 0 0 1.55E+07 1.45E+07 - - - 5.1341 0.9985 221125_WJC_METTL3_EV_vs_WT_F07.11549.11549.2 0.0699 14-Jul K.VGVNGFGR.L sp|P04406|G3P_HUMAN 1 804.4242 0.98 99204 11549 2 804.42269 403.2194 Glyceraldehyde-3-phosphate dehydrogenase OS=Homo sapiens OX=9606 GN=GAPDH PE=1 SV=3 9.72 2211.3 - 338159 - - - -1.9219 - 1.459 0.334 - 122 1 2 0 -0.0015 8 0 0 0 5.85E+06 5.99E+06 - - - 2.6467 0.9995 221125_WJC_METTL3_EV_vs_WT_F07.11554.11554.3 0.00765 Nov-52 K.AVQLKPRPPQGLVR.V "sp|Q13724|MOGS_HUMAN,tr|A0A3B3IRK6|A0A3B3IRK6_HUMAN,tr|A0A3B3IRW2|A0A3B3IRW2_HUMAN" 3 1557.9467 0.75 99207 11554 3 1557.947446 520.3229 Mannosyl-oligosaccharide glucosidase OS=Homo sapiens OX=9606 GN=MOGS PE=1 SV=5 12.01 2211.9 - 1.52E+06 - - - 0.4596 - 1.842 0.334 - 152 1 2 0 0.0007 14 0 0 0 2.84E+07 3.79E+07 - - - 3.8869 0.9045 221125_WJC_METTL3_EV_vs_WT_F07.11555.11555.3 2.94 Aug-48 K.LGHPDTLNQGEFK.E sp|P06702|S10A9_HUMAN 1 1454.7154 1.79 99208 11555 3 1454.716607 485.9124 Protein S100-A9 OS=Homo sapiens OX=9606 GN=S100A9 PE=1 SV=1 5.32 2212 - 971694 - - - 0.8345 - 1.418 0.09 - 60.6 1 2 0 0.0012 13 0 0 0 2.19E+07 1.22E+07 - - - 0.49 1 221125_WJC_METTL3_EV_vs_WT_F07.11556.11556.3 5.99E-07 13/48 K.VADWTGATYQDKR.Y "sp|O15371|EIF3D_HUMAN,tr|B0QYA8|B0QYA8_HUMAN,tr|B0QYA6|B0QYA6_HUMAN,tr|B0QYA5|B0QYA5_HUMAN" 4 1509.7212 0.99 99209 11556 3 1509.719901 504.2477 Eukaryotic translation initiation factor 3 subunit D OS=Homo sapiens OX=9606 GN=EIF3D PE=1 SV=1 5.93 2212.1 - 1.04E+06 - - - -0.8644 - 2.596 0.482 - 260.5 1 2 0 -0.0013 13 0 0 0 1.41E+07 1.43E+07 - - - 6.5 0.9999 221125_WJC_METTL3_EV_vs_WT_F07.11557.11557.4 5.30E-05 Nov-72 M.PAYFQR[166.11]PENALK[136.11]R[166.11].A sp|Q14152|EIF3A_HUMAN 1 1616.8782 1.11 99210 11557 4 1616.877224 405.2268 Eukaryotic translation initiation factor 3 subunit A OS=Homo sapiens OX=9606 GN=EIF3A PE=1 SV=1 10 2212.2 - 325961 - - - -0.5727 - 2.028 0.418 - 85.3 1 2 0 -0.0009 13 0 0 0 4.43E+07 3.98E+07 - - - 3.1262 1 221125_WJC_METTL3_EV_vs_WT_F07.11558.11558.2 4.04E-09 24-Sep K.EWNDSTSVQNPTR[166.11].L "sp|Q9Y3Z3|SAMH1_HUMAN,tr|A0A2R8YDI8|A0A2R8YDI8_HUMAN" 2 1542.6938 0.39 99211 11558 2 1542.702079 772.3542 Deoxynucleoside triphosphate triphosphohydrolase SAMHD1 OS=Homo sapiens OX=9606 GN=SAMHD1 PE=1 SV=2 4.37 2212.3 - 284854 - - - 5.3543 - 2.195 0.647 - 305.2 1 2 0 0.0083 13 0 0 0 3.62E+06 9.26E+06 - - - 5.8349 0.9999 221125_WJC_METTL3_EV_vs_WT_F07.11559.11559.2 6.17E-05 22-Nov R.SLASDITDEQKK.V "sp|P16083|NQO2_HUMAN,tr|Q5TD07|Q5TD07_HUMAN,tr|Q5TD05|Q5TD05_HUMAN" 3 1333.6725 0.42 99212 11559 2 1333.670889 667.8435 Ribosyldihydronicotinamide dehydrogenase [quinone] OS=Homo sapiens OX=9606 GN=NQO2 PE=1 SV=5 4.56 2212.5 - 232244 - - - -1.2267 - 2.237 0.521 - 295.7 1 2 0 -0.0016 12 0 0 0 1.39E+07 3.28E+07 - - - 5.007 0.9999 221125_WJC_METTL3_EV_vs_WT_F07.11564.11564.3 8.69E-08 17/48 R.NVMEEGKDFQPSR.S "sp|P35606|COPB2_HUMAN,tr|H0Y938|H0Y938_HUMAN,tr|A0A7I2V258|A0A7I2V258_HUMAN,tr|H0YAC7|H0YAC7_HUMAN" 4 1535.7038 0.48 99215 11564 3 1535.704962 512.9086 Coatomer subunit beta' OS=Homo sapiens OX=9606 GN=COPB2 PE=1 SV=2 4.68 2213.1 - 952014 - - - 0.7293 - 2.745 0.535 - 376.5 1 2 1 0.0011 13 0 0 0 1.65E+07 3.47E+07 - - - 7.2422 1 221125_WJC_METTL3_EV_vs_WT_F07.11565.11565.3 0.00149 14/60 R.NDIASHPPVEGSYAPR[166.11].R "sp|Q7KZF4|SND1_HUMAN,tr|H7C597|H7C597_HUMAN" 2 1718.8252 0.68 99216 11565 3 1718.825332 573.949 Staphylococcal nuclease domain-containing protein 1 OS=Homo sapiens OX=9606 GN=SND1 PE=1 SV=1 5.32 2213.2 - 2.53E+06 - - - 0.0954 - 2.865 0.446 - 241.4 1 2 0 0.0002 16 0 0 0 2.77E+07 4.10E+07 - - - 6.2132 0.9999 221125_WJC_METTL3_EV_vs_WT_F07.11567.11567.3 2.19E-06 16/44 R.RQQEQQVPILEK.F "sp|P49327|FAS_HUMAN,tr|A0A0U1RQF0|A0A0U1RQF0_HUMAN" 2 1494.8154 0.66 99218 11567 3 1494.815248 499.2791 Fatty acid synthase OS=Homo sapiens OX=9606 GN=FASN PE=1 SV=3 6.14 2213.4 - 599761 - - - -0.1291 - 3.022 0.348 - 533.5 1 2 0 -0.0002 12 0 0 0 8.34E+06 1.27E+07 - - - 5.4852 0.9872 221125_WJC_METTL3_EV_vs_WT_F07.11570.11570.3 2.58E-07 15/52 L.GETYKDHENIVIAK.M "sp|P07237|PDIA1_HUMAN,tr|A0A7P0TA97|A0A7P0TA97_HUMAN,tr|A0A7P0T8C0|A0A7P0T8C0_HUMAN,tr|H7BZ94|H7BZ94_HUMAN,tr|B3KTQ9|B3KTQ9_HUMAN,tr|A0A7P0TA71|A0A7P0TA71_HUMAN,tr|I3L4M2|I3L4M2_HUMAN,tr|A0A7P0T9K9|A0A7P0T9K9_HUMAN,tr|H0Y3Z3|H0Y3Z3_HUMAN,tr|A0A7P0TA35|A0A7P0TA35_HUMAN,tr|A0A7P0TB26|A0A7P0TB26_HUMAN,tr|A0A7P0T9U6|A0A7P0T9U6_HUMAN,tr|I3L0S0|I3L0S0_HUMAN,tr|I3L3P5|I3L3P5_HUMAN,tr|A0A7P0T8J3|A0A7P0T8J3_HUMAN,tr|A0A7P0T8X1|A0A7P0T8X1_HUMAN" 16 1615.8206 1.09 99221 11570 3 1615.820839 539.6141 Protein disulfide-isomerase OS=Homo sapiens OX=9606 GN=P4HB PE=1 SV=3 5.45 2213.8 - 274815 - - - 0.1566 - 2.397 0.519 - 261.4 1 1 1 0.0003 14 0 0 0 4.47E+06 4.11E+06 - - - 6.6495 1 221125_WJC_METTL3_EV_vs_WT_F07.11574.11574.3 9.42E-08 14/52 K.KEISEGDEVEVYSR.A "sp|P51114|FXR1_HUMAN,tr|C9JAJ4|C9JAJ4_HUMAN,tr|B4DXZ6|B4DXZ6_HUMAN" 3 1638.7737 2.49 99223 11574 3 1638.775522 547.2652 Fragile X mental retardation syndrome-related protein 1 OS=Homo sapiens OX=9606 GN=FXR1 PE=1 SV=3 4.25 2214.3 - 1.52E+06 - - - 1.1149 - 2.619 0.568 - 332.7 1 2 0 0.0018 14 0 0 0 2.20E+07 8.84E+06 - - - 7.4308 1 221125_WJC_METTL3_EV_vs_WT_F07.11575.11575.3 0.00151 20/48 R.EHFQHVAAPYIAK[136.11].A "sp|Q9H2P0|ADNP_HUMAN,tr|A0A669KBJ7|A0A669KBJ7_HUMAN" 2 1517.787 1.41 99224 11575 3 1517.78817 506.9363 Activity-dependent neuroprotector homeobox protein OS=Homo sapiens OX=9606 GN=ADNP PE=1 SV=1 7.01 2214.5 - 1.17E+06 - - - 0.7392 - 3.492 0.535 - 591.8 1 2 0 0.0011 13 0 0 0 3.39E+07 2.41E+07 - - - 7.8948 0.9999 221125_WJC_METTL3_EV_vs_WT_F07.11576.11576.3 0.000219 16/52 K.K[136.11]EISEGDEVEVYSR[166.11].A "sp|P51114|FXR1_HUMAN,tr|C9JAJ4|C9JAJ4_HUMAN,tr|B4DXZ6|B4DXZ6_HUMAN" 3 1656.7962 2.49 99225 11576 3 1656.797623 553.2727 Fragile X mental retardation syndrome-related protein 1 OS=Homo sapiens OX=9606 GN=FXR1 PE=1 SV=3 4.25 2214.6 - 804997 - - - 0.88 - 2.416 0.37 - 467.1 1 2 0 0.0015 14 0 0 0 2.20E+07 8.84E+06 - - - 5.009 1 221125_WJC_METTL3_EV_vs_WT_F07.11578.11578.2 3.61E-11 14/28 K.TYTSTSNNSISGSLK.R "sp|P55197|AF10_HUMAN,tr|Q5JT35|Q5JT35_HUMAN" 2 1558.7475 4.09 99227 11578 2 1558.746315 780.381 Protein AF-10 OS=Homo sapiens OX=9606 GN=MLLT10 PE=1 SV=2 8.26 2214.8 - 736365 - - - -0.748 - 2.736 0.72 - 421 1 2 0 -0.0012 15 0 0 0 9.53E+06 2.33E+06 - - - 6.8331 0.9994 221125_WJC_METTL3_EV_vs_WT_F07.11581.11581.3 0.000918 Sep-56 R.ISDHSETPNMELSC[160.03]R.N sp|Q96BU1|S1PBP_HUMAN 1 1774.7614 1.89 99230 11581 3 1774.764683 592.5944 S100P-binding protein OS=Homo sapiens OX=9606 GN=S100PBP PE=1 SV=1 4.65 2215.2 - 470712 - - - 1.8312 - 1.766 0.369 - 68.1 1 2 0 0.0032 15 0 0 0 3.48E+06 1.84E+06 - - - 4.1371 0.9993 221125_WJC_METTL3_EV_vs_WT_F07.11583.11583.3 0.00964 Nov-60 K.LIQNNHYAMEDVATRR.D "sp|Q13813|SPTN1_HUMAN,tr|A0A0D9SF54|A0A0D9SF54_HUMAN,tr|A0A0D9SGF6|A0A0D9SGF6_HUMAN" 3 1929.9479 1.91 99232 11583 3 1929.950355 644.3233 "Spectrin alpha chain, non-erythrocytic 1 OS=Homo sapiens OX=9606 GN=SPTAN1 PE=1 SV=3" 6.75 2215.5 - 409434 - - - 1.257 - 1.904 0.322 - 135.4 1 2 0 0.0024 16 0 0 0 4.17E+06 2.18E+06 - - - 3.7816 1 221125_WJC_METTL3_EV_vs_WT_F07.11585.11585.2 2.88E-09 13/30 K.TIAQGNLSNTDVQAAK.N "sp|P22695|QCR2_HUMAN,tr|H3BRG4|H3BRG4_HUMAN" 2 1629.8322 1.98 99234 11585 2 1629.832673 815.9234 "Cytochrome b-c1 complex subunit 2, mitochondrial OS=Homo sapiens OX=9606 GN=UQCRC2 PE=1 SV=3" 5.5 2215.7 - 307658 - - - 0.2822 - 2.909 0.569 - 399.6 1 2 0 0.0005 16 0 0 0 5.18E+06 2.61E+06 - - - 5.8687 0.7942 221125_WJC_METTL3_EV_vs_WT_F07.11586.11586.3 0.314 Aug-60 K.LIQNNHYAMEDVATR[166.11]R[166.11].D "sp|Q13813|SPTN1_HUMAN,tr|A0A0D9SF54|A0A0D9SF54_HUMAN,tr|A0A0D9SGF6|A0A0D9SGF6_HUMAN" 3 1949.9645 1.79 99235 11586 3 1949.966345 650.9954 "Spectrin alpha chain, non-erythrocytic 1 OS=Homo sapiens OX=9606 GN=SPTAN1 PE=1 SV=3" 6.75 2215.9 - 291147 - - - 0.9621 - 1.405 0.056 - 59.5 1 2 0 0.0019 16 0 0 0 3.90E+06 2.18E+06 - - - 0.0363 1 221125_WJC_METTL3_EV_vs_WT_F07.11587.11587.2 7.05E-10 14/28 K.TYTSTSNNSISGSLK[136.11].R "sp|P55197|AF10_HUMAN,tr|Q5JT35|Q5JT35_HUMAN" 2 1566.7617 4.68 99236 11587 2 1566.76854 784.3881 Protein AF-10 OS=Homo sapiens OX=9606 GN=MLLT10 PE=1 SV=2 8.26 2216 - 194464 - - - 4.3778 - 2.536 0.656 - 421.8 1 2 0 0.0069 15 0 0 0 9.53E+06 2.04E+06 - - - 6.172 0.9979 221125_WJC_METTL3_EV_vs_WT_F07.11590.11590.3 3.21E-08 13/56 F.SVNGSGHFC[160.03]GVAEMK.S "sp|Q9Y5A9|YTHD2_HUMAN,sp|Q9BYJ9|YTHD1_HUMAN,sp|Q7Z739|YTHD3_HUMAN,tr|A0A087X0Q1|A0A087X0Q1_HUMAN,tr|A0A024R7W5|A0A024R7W5_HUMAN,tr|A0A087WY31|A0A087WY31_HUMAN" 6 1578.6919 0.75 99238 11590 3 1578.691059 527.2379 YTH domain-containing family protein 2 OS=Homo sapiens OX=9606 GN=YTHDF2 PE=1 SV=2 6.46 2216.3 - 1.15E+06 - - - -0.5308 - 2.488 0.553 - 115.5 1 1 0 -0.0008 15 0 0 0 7.02E+06 9.31E+06 - - - 7.0836 1 221125_WJC_METTL3_EV_vs_WT_F07.11591.11591.3 4.28E-05 18/64 K.R[166.11]LETPEPGQQGLQAAAR[166.11].S "sp|Q9BSJ6|PIMRE_HUMAN,tr|I3L156|I3L156_HUMAN,tr|I3L419|I3L419_HUMAN" 3 1840.9658 1.4 99239 11591 3 1840.963949 614.6626 Protein PIMREG OS=Homo sapiens OX=9606 GN=PIMREG PE=1 SV=1 6.14 2216.5 - 835353 - - - -1.0321 - 3.221 0.461 - 363.7 1 2 0 -0.0019 17 0 0 0 3.04E+07 2.17E+07 - - - 6.6342 1 221125_WJC_METTL3_EV_vs_WT_F07.11592.11592.3 0.000111 16/44 R.SLASDITDEQK[136.11]K[136.11].V "sp|P16083|NQO2_HUMAN,tr|Q5TD07|Q5TD07_HUMAN,tr|Q5TD05|Q5TD05_HUMAN" 3 1349.7009 0.53 99240 11592 3 1349.700668 450.9076 Ribosyldihydronicotinamide dehydrogenase [quinone] OS=Homo sapiens OX=9606 GN=NQO2 PE=1 SV=5 4.56 2216.5 - 7.28E+06 - - - -0.1904 - 3.318 0.546 - 259.2 1 2 0 -0.0003 12 0 0 0 8.63E+07 1.63E+08 - - - 7.9517 0.9999 221125_WJC_METTL3_EV_vs_WT_F07.11593.11593.3 3.02E-06 16/56 K.IK[136.11]GEHPGLSIGDVAK[136.11].K "sp|B2RPK0|HGB1A_HUMAN,sp|P09429|HMGB1_HUMAN,tr|Q5T7C4|Q5T7C4_HUMAN" 3 1535.8642 0.19 99241 11593 3 1535.864866 512.962 Putative high mobility group protein B1-like 1 OS=Homo sapiens OX=9606 GN=HMGB1P1 PE=5 SV=1 6.75 2216.5 - 4.19E+06 - - - 0.4063 - 3.1 0.529 - 204.6 1 2 1 0.0006 15 0 0 0 9.58E+07 4.93E+08 - - - 7.3899 1 221125_WJC_METTL3_EV_vs_WT_F07.11594.11594.2 3.95E-09 15/32 F.GGGAGGGDGGILTANEK.S sp|P35527|K1C9_HUMAN 1 1429.6797 999 99242 11594 2 1429.680263 715.8471 "Keratin, type I cytoskeletal 9 OS=Homo sapiens OX=9606 GN=KRT9 PE=1 SV=3" 4.37 2216.6 - 1.54E+06 - - - 0.3693 - 3.357 0.669 - 769.8 1 1 0 0.0005 17 0 0 0 5.10E+07 0.00E+00 - - - 6.9595 0.9999 221125_WJC_METTL3_EV_vs_WT_F07.11595.11595.4 1.70E-05 13/72 M.PAYFQRPENALKR.A sp|Q14152|EIF3A_HUMAN 1 1588.8474 1.11 99243 11595 4 1588.844418 398.2191 Eukaryotic translation initiation factor 3 subunit A OS=Homo sapiens OX=9606 GN=EIF3A PE=1 SV=1 10 2216.7 - 1.43E+06 - - - -1.8831 - 2.147 0.46 - 124.5 1 2 0 -0.003 13 0 0 0 4.43E+07 3.98E+07 - - - 3.5123 0.9996 221125_WJC_METTL3_EV_vs_WT_F07.11596.11596.4 0.00113 15/84 K.IK[136.11]GEHPGLSIGDVAK[136.11].K "sp|B2RPK0|HGB1A_HUMAN,sp|P09429|HMGB1_HUMAN,tr|Q5T7C4|Q5T7C4_HUMAN" 3 1535.8642 0.19 99244 11596 4 1535.864661 384.9733 Putative high mobility group protein B1-like 1 OS=Homo sapiens OX=9606 GN=HMGB1P1 PE=5 SV=1 6.75 2216.8 - 1.26E+06 - - - 0.2728 - 2.439 0.421 - 116.5 1 2 1 0.0004 15 0 0 0 2.84E+07 1.50E+08 - - - 3.2093 0.9999 221125_WJC_METTL3_EV_vs_WT_F07.11597.11597.2 0.00111 13/22 R.SLASDITDEQK[136.11]K[136.11].V "sp|P16083|NQO2_HUMAN,tr|Q5TD07|Q5TD07_HUMAN,tr|Q5TD05|Q5TD05_HUMAN" 3 1349.7009 0.42 99245 11597 2 1349.700007 675.8577 Ribosyldihydronicotinamide dehydrogenase [quinone] OS=Homo sapiens OX=9606 GN=NQO2 PE=1 SV=5 4.56 2216.9 - 1.10E+06 - - - -0.6802 - 2.764 0.453 - 436.2 1 2 0 -0.0009 12 0 0 0 1.39E+07 3.33E+07 - - - 5.0616 1 221125_WJC_METTL3_EV_vs_WT_F07.11598.11598.3 1.71E-09 23/64 K.RLETPEPGQQGLQAAAR.S "sp|Q9BSJ6|PIMRE_HUMAN,tr|I3L156|I3L156_HUMAN,tr|I3L419|I3L419_HUMAN" 3 1820.9493 1.4 99246 11598 3 1820.948719 607.9904 Protein PIMREG OS=Homo sapiens OX=9606 GN=PIMREG PE=1 SV=1 6.14 2217 - 2.27E+06 - - - -0.324 - 4.145 0.548 - 670 1 2 0 -0.0006 17 0 0 0 3.04E+07 2.17E+07 - - - 8.2417 0.9999 221125_WJC_METTL3_EV_vs_WT_F07.11602.11602.2 5.71E-06 30-Oct K.TIAQGNLSNTDVQAAK[136.11].N "sp|P22695|QCR2_HUMAN,tr|H3BRG4|H3BRG4_HUMAN" 2 1637.8464 1.98 99250 11602 2 1637.846596 819.9305 "Cytochrome b-c1 complex subunit 2, mitochondrial OS=Homo sapiens OX=9606 GN=UQCRC2 PE=1 SV=3" 5.5 2217.5 - 405427 - - - 0.1117 - 2.047 0.563 - 190 1 2 0 0.0002 16 0 0 0 5.18E+06 2.61E+06 - - - 4.9605 0.9998 221125_WJC_METTL3_EV_vs_WT_F07.11607.11607.3 1.51E-05 22/48 K.HFSQGSALILHQR[166.11].L sp|P17028|ZNF24_HUMAN 1 1502.7982 0.75 99253 11607 3 1502.796904 501.94 Zinc finger protein 24 OS=Homo sapiens OX=9606 GN=ZNF24 PE=1 SV=4 9.76 2218.1 - 1.64E+06 - - - -0.8391 - 3.759 0.234 - 802.7 1 2 0 -0.0013 13 0 0 0 3.09E+07 4.12E+07 - - - 4.7387 0.9994 221125_WJC_METTL3_EV_vs_WT_F07.11608.11608.3 0.00514 Sep-48 M.PAYFQR[166.11]PENALK[136.11]R[166.11].A sp|Q14152|EIF3A_HUMAN 1 1616.8782 1.53 99254 11608 3 1616.881437 539.9667 Eukaryotic translation initiation factor 3 subunit A OS=Homo sapiens OX=9606 GN=EIF3A PE=1 SV=1 10 2218.3 - 999365 - - - 2.0329 - 2.046 0.331 - 131.4 1 2 0 0.0033 13 0 0 0 2.89E+07 1.88E+07 - - - 4.1704 0.9999 221125_WJC_METTL3_EV_vs_WT_F07.11609.11609.3 6.24E-06 14/56 K.IKGEHPGLSIGDVAK.K "sp|B2RPK0|HGB1A_HUMAN,sp|P09429|HMGB1_HUMAN,tr|Q5T7C4|Q5T7C4_HUMAN" 3 1519.8358 0.19 99255 11609 3 1519.835969 507.6192 Putative high mobility group protein B1-like 1 OS=Homo sapiens OX=9606 GN=HMGB1P1 PE=5 SV=1 6.75 2218.3 - 1.99E+06 - - - 0.0836 - 2.807 0.472 - 165.8 1 2 1 0.0001 15 0 0 0 9.46E+07 4.92E+08 - - - 6.4955 0.9998 221125_WJC_METTL3_EV_vs_WT_F07.11610.11610.4 0.00245 16/84 R.LTGVSISQVNHK[136.11]PLR[166.11].T "sp|O75955|FLOT1_HUMAN,tr|A0A140T9W4|A0A140T9W4_HUMAN,tr|A0A140T9R1|A0A140T9R1_HUMAN,tr|A0A140T974|A0A140T974_HUMAN" 4 1665.9645 1.54 99256 11610 4 1665.964206 417.4984 Flotillin-1 OS=Homo sapiens OX=9606 GN=FLOT1 PE=1 SV=3 11 2218.5 - 882205 - - - -0.1819 - 2.984 0.368 - 277.8 1 2 0 -0.0003 15 0 0 0 3.70E+07 2.41E+07 - - - 2.8202 0.9999 221125_WJC_METTL3_EV_vs_WT_F07.11611.11611.3 6.02E-05 15/40 R.YSWNVKPNASR.A sp|O75319|DUS11_HUMAN 1 1320.6575 1.02 99257 11611 3 1320.656295 441.2264 RNA\RNP complex-1-interacting phosphatase OS=Homo sapiens OX=9606 GN=DUSP11 PE=1 SV=2 9.99 2218.6 - 791962 - - - -0.9003 - 1.988 0.414 - 261.3 1 2 0 -0.0012 11 0 0 0 3.13E+07 3.07E+07 - - - 5.1074 0.9997 221125_WJC_METTL3_EV_vs_WT_F07.11612.11612.3 0.000151 Dec-36 K.FK[136.11]LNYAVDK[136.11]R[166.11].G sp|Q9H501|ESF1_HUMAN 1 1278.7295 0.74 99258 11612 3 1278.728561 427.2504 ESF1 homolog OS=Homo sapiens OX=9606 GN=ESF1 PE=1 SV=1 9.7 2218.7 - 516942 - - - -0.7163 - 2.048 0.434 - 229.9 1 2 1 -0.0009 10 0 0 0 2.64E+06 3.58E+06 - - - 5.472 0.9992 221125_WJC_METTL3_EV_vs_WT_F07.11614.11614.2 0.00158 13/26 K.QAEETYENIPGQSK[136.11].L "sp|O00410|IPO5_HUMAN,tr|E7ETV3|E7ETV3_HUMAN,tr|E7ETV8|E7ETV8_HUMAN,tr|C9JXE0|C9JXE0_HUMAN,tr|C9JQT6|C9JQT6_HUMAN,tr|C9JZD8|C9JZD8_HUMAN,tr|E7EWK4|E7EWK4_HUMAN,tr|E7EV12|E7EV12_HUMAN,tr|E7EX05|E7EX05_HUMAN,tr|C9J875|C9J875_HUMAN,tr|E7EQT5|E7EQT5_HUMAN,tr|E7ESZ1|E7ESZ1_HUMAN" 12 1600.746 1.15 99260 11614 2 1600.740336 801.3803 Importin-5 OS=Homo sapiens OX=9606 GN=IPO5 PE=1 SV=4 4.25 2219 - 348768 - - - -3.5577 - 2.506 0.49 - 330.6 1 2 0 -0.0057 14 0 0 0 8.73E+06 7.58E+06 - - - 4.9638 1 221125_WJC_METTL3_EV_vs_WT_F07.11615.11615.2 2.06E-06 13/28 K.IK[136.11]GEHPGLSIGDVAK[136.11].K "sp|B2RPK0|HGB1A_HUMAN,sp|P09429|HMGB1_HUMAN,tr|Q5T7C4|Q5T7C4_HUMAN" 3 1535.8642 0.13 99261 11615 2 1535.864587 768.9394 Putative high mobility group protein B1-like 1 OS=Homo sapiens OX=9606 GN=HMGB1P1 PE=5 SV=1 6.75 2219.1 - 168384 - - - 0.2246 - 3.192 0.523 - 466.6 1 2 1 0.0003 15 0 0 0 1.65E+06 1.30E+07 - - - 5.7573 0.9997 221125_WJC_METTL3_EV_vs_WT_F07.11619.11619.3 0.0116 Aug-48 M.PAYFQRPENALKR.A sp|Q14152|EIF3A_HUMAN 1 1588.8474 1.54 99263 11619 3 1588.846445 530.6231 Eukaryotic translation initiation factor 3 subunit A OS=Homo sapiens OX=9606 GN=EIF3A PE=1 SV=1 10 2219.6 - 1.75E+06 - - - -0.6074 - 1.953 0.351 - 104.4 1 2 0 -0.001 13 0 0 0 2.90E+07 1.88E+07 - - - 4.2679 0.9998 221125_WJC_METTL3_EV_vs_WT_F07.11626.11626.2 3.59E-05 24-Oct K.K[136.11]PLPDHVSIVEPK[136.11].D "sp|P23396|RS3_HUMAN,tr|H0YEU2|H0YEU2_HUMAN,tr|E9PSF4|E9PSF4_HUMAN,tr|E9PL09|E9PL09_HUMAN,tr|E9PPU1|E9PPU1_HUMAN" 5 1473.8526 0.53 99270 11626 2 1473.852125 737.9336 40S ribosomal protein S3 OS=Homo sapiens OX=9606 GN=RPS3 PE=1 SV=2 6.75 2220.4 - 241853 - - - -0.3325 - 2.325 0.427 - 268.5 1 2 0 -0.0005 13 0 0 0 3.55E+06 6.64E+06 - - - 4.3601 0.9992 221125_WJC_METTL3_EV_vs_WT_F07.11632.11632.3 0.000108 16/48 K.HFSQGSALILHQR.L sp|P17028|ZNF24_HUMAN 1 1492.7899 0.74 99274 11632 3 1492.790994 498.6039 Zinc finger protein 24 OS=Homo sapiens OX=9606 GN=ZNF24 PE=1 SV=4 9.76 2221.2 - 3.46E+06 - - - 0.7362 - 3.093 0.167 - 444.6 1 2 0 0.0011 13 0 0 0 3.09E+07 4.19E+07 - - - 3.463 1 221125_WJC_METTL3_EV_vs_WT_F07.11633.11633.2 2.79E-09 26-Nov K.QAEETYENIPGQSK.L "sp|O00410|IPO5_HUMAN,tr|E7ETV3|E7ETV3_HUMAN,tr|E7ETV8|E7ETV8_HUMAN,tr|C9JXE0|C9JXE0_HUMAN,tr|C9JQT6|C9JQT6_HUMAN,tr|C9JZD8|C9JZD8_HUMAN,tr|E7EWK4|E7EWK4_HUMAN,tr|E7EV12|E7EV12_HUMAN,tr|E7EX05|E7EX05_HUMAN,tr|C9J875|C9J875_HUMAN,tr|E7EQT5|E7EQT5_HUMAN,tr|E7ESZ1|E7ESZ1_HUMAN" 12 1592.7318 1.16 99275 11633 2 1592.729813 797.3732 Importin-5 OS=Homo sapiens OX=9606 GN=IPO5 PE=1 SV=4 4.25 2221.3 - 733221 - - - -1.267 - 2.408 0.613 - 238.3 1 2 0 -0.002 14 0 0 0 8.90E+06 7.69E+06 - - - 5.7733 0.9997 221125_WJC_METTL3_EV_vs_WT_F07.11643.11643.3 6.22E-07 Dec-52 R.NGALDQQKDELDVR.L sp|P12270|TPR_HUMAN 1 1599.7853 1.96 99283 11643 3 1599.78868 534.269 Nucleoprotein TPR OS=Homo sapiens OX=9606 GN=TPR PE=1 SV=3 4.23 2222.6 - 1.51E+06 - - - 2.1359 - 2.494 0.494 - 158.4 1 2 1 0.0034 14 0 0 0 3.65E+07 1.86E+07 - - - 6.4754 1 221125_WJC_METTL3_EV_vs_WT_F07.11647.11647.3 1.34E-05 Dec-60 R.NEQNGAAAHVIAEDVK[136.11].L "sp|P24928|RPB1_HUMAN,tr|A0A6Q8PGB0|A0A6Q8PGB0_HUMAN" 2 1672.826 3.19 99287 11647 3 1672.82609 558.6159 DNA-directed RNA polymerase II subunit RPB1 OS=Homo sapiens OX=9606 GN=POLR2A PE=1 SV=2 4.65 2222.9 - 658435 - - - 0.0466 - 2.624 0.495 - 178.1 1 2 0 0.0001 16 0 0 0 3.50E+07 1.09E+07 - - - 6.534 0.9839 221125_WJC_METTL3_EV_vs_WT_F07.11648.11648.3 0.0222 Dec-36 R.K[136.11]IELFGR[166.11]PHN.V sp|Q86U44|MTA70_HUMAN 1 1227.6843 0.33 99288 11648 3 1227.684362 410.2354 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 8.75 2223 - 509517 - - - 0.0415 - 2.387 0.332 - 163.5 1 1 0 0.0001 10 0 0 0 3.75E+07 1.14E+08 - - - 4.7823 1 221125_WJC_METTL3_EV_vs_WT_F07.11653.11653.3 2.72E-05 13/40 R.YSWNVK[136.11]PNASR[166.11].A sp|O75319|DUS11_HUMAN 1 1338.68 1.03 99292 11653 3 1338.680098 447.2339 RNA\RNP complex-1-interacting phosphatase OS=Homo sapiens OX=9606 GN=DUSP11 PE=1 SV=2 9.99 2223.6 - 2.61E+06 - - - 0.1076 - 2.236 0.501 - 179.3 1 2 0 0.0001 11 0 0 0 3.13E+07 3.03E+07 - - - 6.4116 0.9999 221125_WJC_METTL3_EV_vs_WT_F07.11655.11655.3 3.52E-05 15/48 R.LQEKEDLQELNDR.L "sp|P02545|LMNA_HUMAN,tr|A0A6Q8PF80|A0A6Q8PF80_HUMAN,tr|A0A804HL68|A0A804HL68_HUMAN,tr|A0A6Q8PFM1|A0A6Q8PFM1_HUMAN,tr|A0A6Q8PF59|A0A6Q8PF59_HUMAN,tr|A0A6Q8PFJ0|A0A6Q8PFJ0_HUMAN,tr|A0A6Q8PHQ9|A0A6Q8PHQ9_HUMAN,tr|A0A6Q8PGH0|A0A6Q8PGH0_HUMAN,tr|Q3BDU5|Q3BDU5_HUMAN" 9 1628.8006 1.58 99294 11655 3 1628.801191 543.9408 Prelamin-A\C OS=Homo sapiens OX=9606 GN=LMNA PE=1 SV=1 4.18 2223.8 - 1.80E+06 - - - 0.3757 - 3.309 0.476 - 465.8 1 2 1 0.0006 13 0 0 0 4.61E+07 2.92E+07 - - - 7.0912 0.9999 221125_WJC_METTL3_EV_vs_WT_F07.11657.11657.4 1.06E-06 13/72 R.IHQESELHSYLSR[166.11].L "sp|Q9UNE7|CHIP_HUMAN,tr|H3BUD0|H3BUD0_HUMAN,tr|H3BS86|H3BS86_HUMAN,tr|H3BTA3|H3BTA3_HUMAN" 4 1607.7931 0.26 99296 11657 4 1607.792723 402.9556 E3 ubiquitin-protein ligase CHIP OS=Homo sapiens OX=9606 GN=STUB1 PE=1 SV=2 6 2224.1 - 818357 - - - -0.2587 - 3.116 0.417 - 214.6 1 2 0 -0.0004 13 0 0 0 2.03E+06 7.85E+06 - - - 3.2769 0.9934 221125_WJC_METTL3_EV_vs_WT_F07.11663.11663.4 0.000905 Dec-84 R.VFYELQHSDKPVGTK.K "sp|Q93009|UBP7_HUMAN,tr|A0A669KBL1|A0A669KBL1_HUMAN,tr|F5H2X1|F5H2X1_HUMAN,tr|H3BND8|H3BND8_HUMAN" 4 1746.8941 1.15 99300 11663 4 1746.888444 437.7308 Ubiquitin carboxyl-terminal hydrolase 7 OS=Homo sapiens OX=9606 GN=USP7 PE=1 SV=2 6.72 2224.8 - 1.90E+06 - - - -3.2292 - 2.271 0.262 - 74.8 1 2 0 -0.0056 15 0 0 0 3.84E+07 3.36E+07 - - - 1.7984 1 221125_WJC_METTL3_EV_vs_WT_F07.11664.11664.3 2.17E-06 15/56 R.VFYELQHSDKPVGTK.K "sp|Q93009|UBP7_HUMAN,tr|A0A669KBL1|A0A669KBL1_HUMAN,tr|F5H2X1|F5H2X1_HUMAN,tr|H3BND8|H3BND8_HUMAN" 4 1746.8941 0.97 99301 11664 3 1746.892855 583.3053 Ubiquitin carboxyl-terminal hydrolase 7 OS=Homo sapiens OX=9606 GN=USP7 PE=1 SV=2 6.72 2224.8 - 2.43E+06 - - - -0.7041 - 3.039 0.604 - 301.4 1 2 0 -0.0012 15 0 0 0 4.24E+07 4.36E+07 - - - 8.174 1 221125_WJC_METTL3_EV_vs_WT_F07.11667.11667.4 5.38E-13 22/84 K.KLLVPAAEGEDSLKK.M "sp|Q96PU8|QKI_HUMAN,tr|F5GYM3|F5GYM3_HUMAN,tr|F5GXS8|F5GXS8_HUMAN,tr|H0YG47|H0YG47_HUMAN,tr|H0YGD6|H0YGD6_HUMAN" 5 1596.9087 2.43 99304 11667 4 1596.909092 400.2344 Protein quaking OS=Homo sapiens OX=9606 GN=QKI PE=1 SV=1 6.18 2225.1 - 779693 - - - 0.2624 - 3.876 0.642 - 478.7 1 2 0 0.0004 15 0 0 0 2.98E+07 1.23E+07 - - - 5.2986 1 221125_WJC_METTL3_EV_vs_WT_F07.11668.11668.3 4.91E-08 20/60 R.R[166.11]IPPPGSQPPVLNTSR[166.11].E "sp|Q5JSZ5|PRC2B_HUMAN,tr|A0A804HKU3|A0A804HKU3_HUMAN,tr|A0A804HJR4|A0A804HJR4_HUMAN" 3 1734.9644 2.63 99305 11668 3 1734.967448 579.3287 Protein PRRC2B OS=Homo sapiens OX=9606 GN=PRRC2B PE=1 SV=2 12 2225.3 - 718094 - - - 1.7614 - 3.495 0.574 - 666.5 1 2 0 0.0031 16 0 0 0 3.65E+07 1.39E+07 - - - 8.1494 0.9629 221125_WJC_METTL3_EV_vs_WT_F07.11671.11671.2 0.728 14-Jun K.LGDYGLAK.K "sp|Q8TD19|NEK9_HUMAN,tr|A0A7I2V5R1|A0A7I2V5R1_HUMAN,tr|G3V2Z5|G3V2Z5_HUMAN,tr|A0A7I2V454|A0A7I2V454_HUMAN,tr|G3V5V0|G3V5V0_HUMAN" 5 835.444 2.48 99308 11671 2 835.44229 418.7293 Serine\threonine-protein kinase Nek9 OS=Homo sapiens OX=9606 GN=NEK9 PE=1 SV=2 5.83 2225.7 - 587618 - - - -2.0097 - 1.404 0.054 - 51.4 3 2 0 -0.0017 8 0 0 0 8.04E+06 3.25E+06 - - - 0.2496 0.9997 221125_WJC_METTL3_EV_vs_WT_F07.11676.11676.4 0.000227 14/84 R.VFYELQHSDK[136.11]PVGTK[136.11].K "sp|Q93009|UBP7_HUMAN,tr|A0A669KBL1|A0A669KBL1_HUMAN,tr|F5H2X1|F5H2X1_HUMAN,tr|H3BND8|H3BND8_HUMAN" 4 1762.9225 1.15 99311 11676 4 1762.923727 441.7379 Ubiquitin carboxyl-terminal hydrolase 7 OS=Homo sapiens OX=9606 GN=USP7 PE=1 SV=2 6.72 2226.4 - 2.97E+06 - - - 0.7045 - 2.37 0.353 - 89.6 1 2 0 0.0012 15 0 0 0 3.84E+07 3.36E+07 - - - 2.6069 0.9981 221125_WJC_METTL3_EV_vs_WT_F07.11679.11679.3 0.0671 Nov-36 K.KLEDLGDLRR.Q sp|Q86VS8|HOOK3_HUMAN 1 1213.6779 3.87 99314 11679 3 1213.678572 405.5666 Protein Hook homolog 3 OS=Homo sapiens OX=9606 GN=HOOK3 PE=1 SV=2 6.12 2226.5 - 1.49E+06 - - - 0.566 - 1.946 0.215 - 202.8 1 2 0 0.0007 10 0 0 0 1.45E+07 3.74E+06 - - - 2.8812 0.9999 221125_WJC_METTL3_EV_vs_WT_F07.11682.11682.3 5.72E-05 14/76 K.TPASGLQTPTSTPAPGSATR.T sp|Q96DF8|ESS2_HUMAN 1 1896.9541 1.87 99317 11682 3 1896.955087 633.3253 Splicing factor ESS-2 homolog OS=Homo sapiens OX=9606 GN=ESS2 PE=1 SV=1 9.41 2226.7 - 836949 - - - 0.5098 - 2.469 0.452 - 159.9 1 2 0 0.001 20 0 0 0 8.53E+07 4.56E+07 - - - 5.7718 1 221125_WJC_METTL3_EV_vs_WT_F07.11684.11684.3 5.28E-06 22/76 K.TPASGLQTPTSTPAPGSATR[166.11].T sp|Q96DF8|ESS2_HUMAN 1 1906.9624 1.87 99319 11684 3 1906.965414 636.6614 Splicing factor ESS-2 homolog OS=Homo sapiens OX=9606 GN=ESS2 PE=1 SV=1 9.41 2227 - 542194 - - - 1.5858 - 3.913 0.492 - 455.4 1 2 0 0.003 20 0 0 0 8.53E+07 4.56E+07 - - - 7.3343 1 221125_WJC_METTL3_EV_vs_WT_F07.11685.11685.2 6.06E-09 16/38 K.TPASGLQTPTSTPAPGSATR.T sp|Q96DF8|ESS2_HUMAN 1 1896.9541 1.92 99320 11685 2 1896.955236 949.4843 Splicing factor ESS-2 homolog OS=Homo sapiens OX=9606 GN=ESS2 PE=1 SV=1 9.41 2227.1 - 368371 - - - 0.5883 - 3.58 0.686 - 441.9 1 2 0 0.0011 20 0 0 0 4.55E+07 2.37E+07 - - - 7.243 0.9989 221125_WJC_METTL3_EV_vs_WT_F07.11686.11686.2 4.67E-06 24-Dec R.LQEKEDLQELNDR.L "sp|P02545|LMNA_HUMAN,tr|A0A6Q8PF80|A0A6Q8PF80_HUMAN,tr|A0A804HL68|A0A804HL68_HUMAN,tr|A0A6Q8PFM1|A0A6Q8PFM1_HUMAN,tr|A0A6Q8PF59|A0A6Q8PF59_HUMAN,tr|A0A6Q8PFJ0|A0A6Q8PFJ0_HUMAN,tr|A0A6Q8PHQ9|A0A6Q8PHQ9_HUMAN,tr|A0A6Q8PGH0|A0A6Q8PGH0_HUMAN,tr|Q3BDU5|Q3BDU5_HUMAN" 9 1628.8006 4.49 99321 11686 2 1628.801538 815.4076 Prelamin-A\C OS=Homo sapiens OX=9606 GN=LMNA PE=1 SV=1 4.18 2227.2 - 360038 - - - 0.5888 - 2.773 0.535 - 519.1 1 2 1 0.001 13 0 0 0 2.58E+06 5.74E+05 - - - 5.6099 0.9977 221125_WJC_METTL3_EV_vs_WT_F07.11687.11687.2 1.34E-05 24-Nov R.EVQTNDLKEVVNK.L "sp|P61247|RS3A_HUMAN,tr|D6R9B6|D6R9B6_HUMAN,tr|H0Y9Y4|H0Y9Y4_HUMAN,tr|D6RB09|D6RB09_HUMAN,tr|E9PFI5|E9PFI5_HUMAN,tr|D6RAT0|D6RAT0_HUMAN,tr|D6RG13|D6RG13_HUMAN" 7 1514.794 1.18 99322 11687 2 1514.79562 758.4043 40S ribosomal protein S3a OS=Homo sapiens OX=9606 GN=RPS3A PE=1 SV=2 4.68 2227.4 - 203573 - - - 1.045 - 2.067 0.483 - 332.1 1 2 1 0.0016 13 0 0 0 3.15E+06 2.66E+06 - - - 4.4715 0.9996 221125_WJC_METTL3_EV_vs_WT_F07.11691.11691.3 0.000295 Dec-48 R.LQEK[136.11]EDLQELNDR[166.11].L "sp|P02545|LMNA_HUMAN,tr|A0A6Q8PF80|A0A6Q8PF80_HUMAN,tr|A0A804HL68|A0A804HL68_HUMAN,tr|A0A6Q8PFM1|A0A6Q8PFM1_HUMAN,tr|A0A6Q8PF59|A0A6Q8PF59_HUMAN,tr|A0A6Q8PFJ0|A0A6Q8PFJ0_HUMAN,tr|A0A6Q8PHQ9|A0A6Q8PHQ9_HUMAN,tr|A0A6Q8PGH0|A0A6Q8PGH0_HUMAN,tr|Q3BDU5|Q3BDU5_HUMAN" 9 1646.823 1.55 99324 11691 3 1646.824706 549.9483 Prelamin-A\C OS=Homo sapiens OX=9606 GN=LMNA PE=1 SV=1 4.18 2227.8 - 2.04E+06 - - - 1.0062 - 2.629 0.385 - 255 1 2 1 0.0017 13 0 0 0 4.61E+07 2.97E+07 - - - 5.4527 1 221125_WJC_METTL3_EV_vs_WT_F07.11692.11692.3 0.000128 13/44 R.SQQQQLVESLHK.V sp|Q7Z3B4|NUP54_HUMAN 1 1423.7419 1.87 99325 11692 3 1423.743188 475.5879 Nucleoporin p54 OS=Homo sapiens OX=9606 GN=NUP54 PE=1 SV=2 6.47 2227.9 - 2.80E+06 - - - 0.8752 - 2.611 0.462 - 339.1 1 2 0 0.0012 12 0 0 0 4.50E+08 2.41E+08 - - - 6.3507 0.9999 221125_WJC_METTL3_EV_vs_WT_F07.11693.11693.3 1.84E-06 13/44 R.SQQQQLVESLHK[136.11].V sp|Q7Z3B4|NUP54_HUMAN 1 1431.7561 1.87 99326 11693 3 1431.758965 478.2593 Nucleoporin p54 OS=Homo sapiens OX=9606 GN=NUP54 PE=1 SV=2 6.47 2227.9 - 1.82E+06 - - - 1.9717 - 2.373 0.502 - 319.8 1 2 0 0.0028 12 0 0 0 4.50E+08 2.41E+08 - - - 6.5313 1 221125_WJC_METTL3_EV_vs_WT_F07.11694.11694.3 0.00294 18/56 K.K[136.11]LLVPAAEGEDSLK[136.11]K[136.11].M "sp|Q96PU8|QKI_HUMAN,tr|F5GYM3|F5GYM3_HUMAN,tr|F5GXS8|F5GXS8_HUMAN,tr|H0YG47|H0YG47_HUMAN,tr|H0YGD6|H0YGD6_HUMAN" 5 1620.9513 2.58 99327 11694 3 1620.951928 541.3244 Protein quaking OS=Homo sapiens OX=9606 GN=QKI PE=1 SV=1 6.18 2228 - 1.00E+06 - - - 0.4041 - 3.328 0.546 - 360.9 1 2 0 0.0007 15 0 0 0 5.74E+07 2.22E+07 - - - 7.7646 1 221125_WJC_METTL3_EV_vs_WT_F07.11697.11697.2 1.22E-09 19/38 K.TPASGLQTPTSTPAPGSATR[166.11].T sp|Q96DF8|ESS2_HUMAN 1 1906.9624 1.92 99330 11697 2 1906.965413 954.4885 Splicing factor ESS-2 homolog OS=Homo sapiens OX=9606 GN=ESS2 PE=1 SV=1 9.41 2228.4 - 284740 - - - 1.5852 - 3.965 0.671 - 708.2 1 2 0 0.003 20 0 0 0 4.55E+07 2.37E+07 - - - 7.3827 1 221125_WJC_METTL3_EV_vs_WT_F07.11698.11698.2 8.41E-07 28-Dec K.SGAIMC[160.03]ENC[160.03]MTTNQK[136.11].K sp|Q86YP4|P66A_HUMAN 1 1751.719 1.12 99331 11698 2 1751.720286 876.8668 Transcriptional repressor p66-alpha OS=Homo sapiens OX=9606 GN=GATAD2A PE=1 SV=1 5.71 2228.5 - 278475 - - - 0.7073 - 2.623 0.676 - 423.7 1 2 0 0.0012 15 0 0 0 6.67E+06 5.96E+06 - - - 6.4044 1 221125_WJC_METTL3_EV_vs_WT_F07.11699.11699.2 1.62E-08 28-Nov K.SGAIMC[160.03]ENC[160.03]MTTNQK.K sp|Q86YP4|P66A_HUMAN 1 1743.7048 1.12 99332 11699 2 1743.707051 872.8597 Transcriptional repressor p66-alpha OS=Homo sapiens OX=9606 GN=GATAD2A PE=1 SV=1 5.71 2228.6 - 228282 - - - 1.264 - 2.467 0.714 - 311.6 1 2 0 0.0022 15 0 0 0 6.67E+06 5.96E+06 - - - 6.534 0.9921 221125_WJC_METTL3_EV_vs_WT_F07.11703.11703.3 4.25E-06 Nov-72 A.SLAASYAAQQHPQAAASYR[166.11].G sp|Q96PK6|RBM14_HUMAN 1 1999.974 2.75 99336 11703 3 1999.972718 667.6653 RNA-binding protein 14 OS=Homo sapiens OX=9606 GN=RBM14 PE=1 SV=2 8.33 2229.2 - 133055 - - - -0.6195 - 2.147 0.453 - 91.3 1 1 0 -0.0012 19 0 0 0 3.45E+06 1.25E+06 - - - 5.4673 1 221125_WJC_METTL3_EV_vs_WT_F07.11706.11706.3 1.45E-12 23/56 K.KLLVPAAEGEDSLKK.M "sp|Q96PU8|QKI_HUMAN,tr|F5GYM3|F5GYM3_HUMAN,tr|F5GXS8|F5GXS8_HUMAN,tr|H0YG47|H0YG47_HUMAN,tr|H0YGD6|H0YGD6_HUMAN" 5 1596.9087 2.55 99337 11706 3 1596.909672 533.3102 Protein quaking OS=Homo sapiens OX=9606 GN=QKI PE=1 SV=1 6.18 2229.6 - 3.56E+06 - - - 0.6256 - 3.913 0.691 - 886.5 1 2 0 0.001 15 0 0 0 5.68E+07 2.22E+07 - - - 9.8037 0.9997 221125_WJC_METTL3_EV_vs_WT_F07.11707.11707.3 0.0303 14/32 R.EHLLDQLK[136.11]R[166.11].K "sp|P52732|KIF11_HUMAN,tr|A0A7I2V3A9|A0A7I2V3A9_HUMAN" 2 1168.6683 4.39 99338 11707 3 1168.668318 390.5634 Kinesin-like protein KIF11 OS=Homo sapiens OX=9606 GN=KIF11 PE=1 SV=2 6.85 2229.7 - 1.08E+06 - - - -0.0068 - 2.622 0.251 - 389.2 1 2 0 0 9 0 0 0 1.03E+09 2.35E+08 - - - 4.2435 1 221125_WJC_METTL3_EV_vs_WT_F07.11710.11710.2 9.35E-09 22-Dec R.SQQQQLVESLHK[136.11].V sp|Q7Z3B4|NUP54_HUMAN 1 1431.7561 1.84 99341 11710 2 1431.757742 716.8853 Nucleoporin p54 OS=Homo sapiens OX=9606 GN=NUP54 PE=1 SV=2 6.47 2230.1 - 258425 - - - 1.1175 - 2.55 0.624 - 585.6 1 2 0 0.0016 12 0 0 0 2.28E+07 1.24E+07 - - - 6.1124 1 221125_WJC_METTL3_EV_vs_WT_F07.11714.11714.3 1.13E-08 22/48 K.KPLPDHVSIVEPK.D "sp|P23396|RS3_HUMAN,tr|H0YEU2|H0YEU2_HUMAN,tr|E9PSF4|E9PSF4_HUMAN,tr|E9PL09|E9PL09_HUMAN,tr|E9PPU1|E9PPU1_HUMAN" 5 1457.8242 0.76 99344 11714 3 1457.826853 486.9487 40S ribosomal protein S3 OS=Homo sapiens OX=9606 GN=RPS3 PE=1 SV=2 6.75 2230.6 - 9.72E+06 - - - 1.8095 - 3.754 0.632 - 724.3 1 2 0 0.0026 13 0 0 0 2.11E+08 2.79E+08 - - - 9.172 0.9999 221125_WJC_METTL3_EV_vs_WT_F07.11716.11716.3 0.00126 13/44 R.WEYMHSPSENSK[136.11].E sp|P36551|HEM6_HUMAN 1 1501.6387 1.16 99345 11716 3 1501.640712 501.5535 "Oxygen-dependent coproporphyrinogen-III oxidase, mitochondrial OS=Homo sapiens OX=9606 GN=CPOX PE=1 SV=3" 5.4 2230.8 - 1.42E+06 - - - 1.3206 - 2.403 0.446 - 191.9 1 2 0 0.002 12 0 0 0 3.35E+07 2.89E+07 - - - 5.942 1 221125_WJC_METTL3_EV_vs_WT_F07.11717.11717.3 6.85E-09 20/52 R.QDPQSTAAATVLKR.A "sp|Q8WV92|MITD1_HUMAN,tr|F8WED5|F8WED5_HUMAN,tr|B8ZZL5|B8ZZL5_HUMAN,tr|A0A1W2PP14|A0A1W2PP14_HUMAN" 4 1484.7947 1.29 99346 11717 3 1484.797237 495.9388 MIT domain-containing protein 1 OS=Homo sapiens OX=9606 GN=MITD1 PE=1 SV=1 8.75 2230.9 - 652846 - - - 1.7046 - 3.647 0.62 - 558.1 1 2 0 0.0025 14 0 0 0 4.96E+07 3.85E+07 - - - 8.8903 0.9999 221125_WJC_METTL3_EV_vs_WT_F07.11718.11718.2 0.000252 22-Dec R.SQQQQLVESLHK.V sp|Q7Z3B4|NUP54_HUMAN 1 1423.7419 1.84 99347 11718 2 1423.74312 712.8782 Nucleoporin p54 OS=Homo sapiens OX=9606 GN=NUP54 PE=1 SV=2 6.47 2231 - 870020 - - - 0.8274 - 2.5 0.474 - 619.4 1 2 0 0.0012 12 0 0 0 2.28E+07 1.24E+07 - - - 4.9525 1 221125_WJC_METTL3_EV_vs_WT_F07.11722.11722.3 1.19E-10 21/48 K.K[136.11]PLPDHVSIVEPK[136.11].D "sp|P23396|RS3_HUMAN,tr|H0YEU2|H0YEU2_HUMAN,tr|E9PSF4|E9PSF4_HUMAN,tr|E9PL09|E9PL09_HUMAN,tr|E9PPU1|E9PPU1_HUMAN" 5 1473.8526 0.76 99350 11722 3 1473.853887 492.2915 40S ribosomal protein S3 OS=Homo sapiens OX=9606 GN=RPS3 PE=1 SV=2 6.75 2231.5 - 1.62E+07 - - - 0.863 - 3.86 0.635 - 635.9 1 2 0 0.0013 13 0 0 0 2.11E+08 2.79E+08 - - - 9.2813 1 221125_WJC_METTL3_EV_vs_WT_F07.11724.11724.3 0.000114 21/40 R.SLHDALC[160.03]VVK[136.11]R[166.11].V "sp|P17987|TCPA_HUMAN,tr|F5GZ03|F5GZ03_HUMAN,tr|F5H282|F5H282_HUMAN,tr|E7EQR6|E7EQR6_HUMAN,tr|E7ERF2|E7ERF2_HUMAN" 5 1314.7197 0.31 99351 11724 3 1314.720963 439.2472 T-complex protein 1 subunit alpha OS=Homo sapiens OX=9606 GN=TCP1 PE=1 SV=1 7.97 2231.7 - 2.33E+06 - - - 0.9531 - 3.312 0.581 - 910.2 1 2 0 0.0013 11 0 0 0 1.83E+07 5.95E+07 - - - 8.4193 1 221125_WJC_METTL3_EV_vs_WT_F07.11725.11725.3 3.07E-06 Dec-44 K.EYSGFAGVSRPR.G "sp|Q9NYF8|BCLF1_HUMAN,tr|H0YF63|H0YF63_HUMAN,tr|E9PK91|E9PK91_HUMAN,tr|H0YF14|H0YF14_HUMAN" 4 1324.6524 1.75 99352 11725 3 1324.652566 442.5581 Bcl-2-associated transcription factor 1 OS=Homo sapiens OX=9606 GN=BCLAF1 PE=1 SV=2 8.85 2231.7 - 2.41E+06 - - - 0.1268 - 1.966 0.577 - 171.1 1 2 0 0.0002 12 0 0 0 4.64E+07 2.66E+07 - - - 6.8467 0.9999 221125_WJC_METTL3_EV_vs_WT_F07.11726.11726.3 2.66E-05 Dec-44 K.EYSGFAGVSR[166.11]PR[166.11].G "sp|Q9NYF8|BCLF1_HUMAN,tr|H0YF63|H0YF63_HUMAN,tr|E9PK91|E9PK91_HUMAN,tr|H0YF14|H0YF14_HUMAN" 4 1344.6689 1.79 99353 11726 3 1344.670955 449.2303 Bcl-2-associated transcription factor 1 OS=Homo sapiens OX=9606 GN=BCLAF1 PE=1 SV=2 8.85 2231.8 - 1.53E+06 - - - 1.5 - 1.781 0.525 - 229.3 1 2 0 0.002 12 0 0 0 4.61E+07 2.58E+07 - - - 5.9925 1 221125_WJC_METTL3_EV_vs_WT_F07.11727.11727.3 1.55E-07 22/60 R.RIPPPGSQPPVLNTSR.E "sp|Q5JSZ5|PRC2B_HUMAN,tr|A0A804HKU3|A0A804HKU3_HUMAN,tr|A0A804HJR4|A0A804HJR4_HUMAN" 3 1714.9479 2.63 99354 11727 3 1714.949643 572.6566 Protein PRRC2B OS=Homo sapiens OX=9606 GN=PRRC2B PE=1 SV=2 12 2231.9 - 1.32E+06 - - - 1.0443 - 3.554 0.596 - 850.8 1 2 0 0.0018 16 0 0 0 3.65E+07 1.39E+07 - - - 8.438 1 221125_WJC_METTL3_EV_vs_WT_F07.11729.11729.3 1.69E-05 18/56 K.GPNGVYDFSQAHNAK.D sp|Q9Y5V3|MAGD1_HUMAN 1 1603.7379 1.55 99356 11729 3 1603.739308 535.5866 Melanoma-associated antigen D1 OS=Homo sapiens OX=9606 GN=MAGED1 PE=1 SV=3 6.74 2232.1 - 762954 - - - 0.8661 - 3.18 0.579 - 401.7 1 2 0 0.0014 15 0 0 0 7.04E+07 4.54E+07 - - - 8.0136 1 221125_WJC_METTL3_EV_vs_WT_F07.11731.11731.3 1.16E-07 13/44 K.LHGVNINVEASK.N "sp|Q9BWF3|RBM4_HUMAN,sp|Q9BQ04|RBM4B_HUMAN,tr|E9PM61|E9PM61_HUMAN,tr|D6R9K7|D6R9K7_HUMAN,tr|J3QRR5|J3QRR5_HUMAN,tr|E9PB51|E9PB51_HUMAN,tr|U3KQD5|U3KQD5_HUMAN,tr|E9PLB0|E9PLB0_HUMAN" 8 1279.6885 1.41 99358 11731 3 1279.689463 427.5701 RNA-binding protein 4 OS=Homo sapiens OX=9606 GN=RBM4 PE=1 SV=1 6.75 2232.4 - 609700 - - - 0.7916 - 2.723 0.476 - 379.6 1 2 0 0.001 12 0 0 0 3.87E+07 2.75E+07 - - - 6.6233 0.993 221125_WJC_METTL3_EV_vs_WT_F07.11732.11732.4 0.0446 Nov-72 K.LTDIHGNVLQYHK[136.11].D "sp|O95861|BPNT1_HUMAN,tr|A6NF51|A6NF51_HUMAN" 2 1544.8191 0.74 99359 11732 4 1544.823584 387.212 "3'(2'),5'-bisphosphate nucleotidase 1 OS=Homo sapiens OX=9606 GN=BPNT1 PE=1 SV=1" 6.92 2232.5 - 474098 - - - 2.9181 - 1.951 0.256 - 70.2 1 2 0 0.0045 13 0 0 0 1.36E+07 1.83E+07 - - - 1.7008 1 221125_WJC_METTL3_EV_vs_WT_F07.11733.11733.3 1.64E-05 13/44 K.LHGVNINVEASK[136.11].N "sp|Q9BWF3|RBM4_HUMAN,sp|Q9BQ04|RBM4B_HUMAN,tr|E9PM61|E9PM61_HUMAN,tr|D6R9K7|D6R9K7_HUMAN,tr|J3QRR5|J3QRR5_HUMAN,tr|E9PB51|E9PB51_HUMAN,tr|U3KQD5|U3KQD5_HUMAN,tr|E9PLB0|E9PLB0_HUMAN" 8 1287.7026 1.41 99360 11733 3 1287.70262 430.2415 RNA-binding protein 4 OS=Homo sapiens OX=9606 GN=RBM4 PE=1 SV=1 6.75 2232.6 - 412655 - - - -0.0233 - 2.913 0.468 - 417.9 1 2 0 0 12 0 0 0 3.87E+07 2.75E+07 - - - 6.7213 0.9966 221125_WJC_METTL3_EV_vs_WT_F07.11734.11734.3 0.000894 Nov-48 R.GK[136.11]FNTSDVSAIEK[136.11].N sp|P19367|HXK1_HUMAN 1 1410.7326 0.71 99361 11734 3 1410.734582 471.2515 Hexokinase-1 OS=Homo sapiens OX=9606 GN=HK1 PE=1 SV=3 6.07 2232.8 - 393663 - - - 1.434 - 2.15 0.283 - 148.8 1 2 1 0.002 13 0 0 0 4.43E+06 6.24E+06 - - - 3.77 0.9997 221125_WJC_METTL3_EV_vs_WT_F07.11739.11739.3 0.000833 Sep-44 K.DVSHEIIQHEVK[136.11].S "sp|Q7Z6E9|RBBP6_HUMAN,tr|A0A2R8Y880|A0A2R8Y880_HUMAN" 2 1440.7452 0.001 99364 11739 3 1440.745779 481.2557 E3 ubiquitin-protein ligase RBBP6 OS=Homo sapiens OX=9606 GN=RBBP6 PE=1 SV=1 5.27 2233.4 - 1.13E+06 - - - 0.372 - 1.857 0.369 - 75.6 1 2 0 0.0005 12 0 0 0 0.00E+00 1.09E+07 - - - 4.3695 0.9995 221125_WJC_METTL3_EV_vs_WT_F07.11740.11740.2 0.047 16-Sep R.EHLLDQLK[136.11]R[166.11].K "sp|P52732|KIF11_HUMAN,tr|A0A7I2V3A9|A0A7I2V3A9_HUMAN" 2 1168.6683 4.88 99365 11740 2 1168.669149 585.3414 Kinesin-like protein KIF11 OS=Homo sapiens OX=9606 GN=KIF11 PE=1 SV=2 6.85 2233.5 - 726645 - - - 0.7042 - 1.883 0.327 - 402.8 1 2 0 0.0008 9 0 0 0 1.12E+08 2.30E+07 - - - 3.2869 0.9995 221125_WJC_METTL3_EV_vs_WT_F07.11741.11741.2 0.06 16-Sep R.EHLLDQLKR.K "sp|P52732|KIF11_HUMAN,tr|A0A7I2V3A9|A0A7I2V3A9_HUMAN" 2 1150.6459 4.88 99366 11741 2 1150.646498 576.3302 Kinesin-like protein KIF11 OS=Homo sapiens OX=9606 GN=KIF11 PE=1 SV=2 6.85 2233.6 - 2.88E+06 - - - 0.5579 - 1.981 0.291 - 473.9 1 2 0 0.0006 9 0 0 0 1.12E+08 2.30E+07 - - - 3.1678 0.9358 221125_WJC_METTL3_EV_vs_WT_F07.11743.11743.3 0.437 Oct-56 R.AFGHHAVSLLDGGLR.H "sp|P25325|THTM_HUMAN,tr|B1AH49|B1AH49_HUMAN" 2 1548.8161 10.62 99368 11743 3 1548.817563 517.2793 3-mercaptopyruvate sulfurtransferase OS=Homo sapiens OX=9606 GN=MPST PE=1 SV=3 6.96 2233.8 - 1.11E+06 - - - 0.9381 - 1.391 0.121 - 67.2 1 2 0 0.0015 15 0 0 0 1.73E+07 1.63E+06 - - - 0.7498 1 221125_WJC_METTL3_EV_vs_WT_F07.11744.11744.3 3.50E-05 Dec-48 K.LTDIHGNVLQYHK.D "sp|O95861|BPNT1_HUMAN,tr|A6NF51|A6NF51_HUMAN" 2 1536.8049 0.39 99369 11744 3 1536.806724 513.2756 "3'(2'),5'-bisphosphate nucleotidase 1 OS=Homo sapiens OX=9606 GN=BPNT1 PE=1 SV=1" 6.92 2233.8 - 673564 - - - 1.2025 - 2.764 0.454 - 141.5 1 2 0 0.0018 13 0 0 0 1.29E+07 3.30E+07 - - - 6.3577 0.9999 221125_WJC_METTL3_EV_vs_WT_F07.11747.11747.4 1.76E-05 Dec-84 K.K[136.11]LLVPAAEGEDSLK[136.11]K[136.11].M "sp|Q96PU8|QKI_HUMAN,tr|F5GYM3|F5GYM3_HUMAN,tr|F5GXS8|F5GXS8_HUMAN,tr|H0YG47|H0YG47_HUMAN,tr|H0YGD6|H0YGD6_HUMAN" 5 1620.9513 2.43 99372 11747 4 1620.951437 406.2451 Protein quaking OS=Homo sapiens OX=9606 GN=QKI PE=1 SV=1 6.18 2234.1 - 622063 - - - 0.1012 - 2.665 0.455 - 121.3 1 2 0 0.0002 15 0 0 0 2.98E+07 1.23E+07 - - - 3.537 0.8711 221125_WJC_METTL3_EV_vs_WT_F07.11748.11748.3 0.211 Aug-52 R.MEEKDYTVTQVPPK.H "sp|Q8N5Z5|KCD17_HUMAN,tr|A0A087WX35|A0A087WX35_HUMAN,tr|H0Y731|H0Y731_HUMAN" 3 1663.8127 5.73 99373 11748 3 1663.819265 555.6115 BTB\POZ domain-containing protein KCTD17 OS=Homo sapiens OX=9606 GN=KCTD17 PE=1 SV=3 4.68 2234.2 - 567604 - - - 3.9313 - 1.498 0.245 - 66.4 1 2 1 0.0065 14 0 0 0 1.23E+07 2.15E+06 - - - 2.3437 0.9907 221125_WJC_METTL3_EV_vs_WT_F07.11749.11749.3 0.0206 Aug-40 R.DASNWSTDKLK.T "sp|O95433|AHSA1_HUMAN,tr|G3V3W9|G3V3W9_HUMAN" 2 1263.6095 1.66 99374 11749 3 1263.609646 422.2105 Activator of 90 kDa heat shock protein ATPase homolog 1 OS=Homo sapiens OX=9606 GN=AHSA1 PE=1 SV=1 5.96 2234.3 - 529197 - - - 0.091 - 1.501 0.28 - 90 1 2 1 0.0001 11 0 0 0 9.33E+06 5.62E+06 - - - 2.8154 0.9519 221125_WJC_METTL3_EV_vs_WT_F07.11750.11750.3 0.0613 Sep-76 K.GEPGGGPGELAPVGPDEKEK.G sp|P55316|FOXG1_HUMAN 1 1918.9272 15.61 99375 11750 3 1918.932241 640.6497 Forkhead box protein G1 OS=Homo sapiens OX=9606 GN=FOXG1 PE=1 SV=2 4.25 2234.4 - 434108 - - - 2.6082 - 1.895 0.241 - 36 6 2 1 0.005 20 0 0 0 1.01E+07 6.49E+05 - - - 2.4161 0.9996 221125_WJC_METTL3_EV_vs_WT_F07.11753.11753.3 0.000163 13/48 K.LTDIHGNVLQYHK[136.11].D "sp|O95861|BPNT1_HUMAN,tr|A6NF51|A6NF51_HUMAN" 2 1544.8191 0.39 99376 11753 3 1544.821615 515.947 "3'(2'),5'-bisphosphate nucleotidase 1 OS=Homo sapiens OX=9606 GN=BPNT1 PE=1 SV=1" 6.92 2234.8 - 1.35E+06 - - - 1.6436 - 2.335 0.317 - 160.9 1 2 0 0.0025 13 0 0 0 1.29E+07 3.32E+07 - - - 4.3727 0.9707 221125_WJC_METTL3_EV_vs_WT_F07.11754.11754.3 0.107 Sep-36 R.EKLQEEMLQR.E "sp|P08670|VIME_HUMAN,tr|B0YJC4|B0YJC4_HUMAN" 2 1302.6602 0.44 99377 11754 3 1302.661131 435.2273 Vimentin OS=Homo sapiens OX=9606 GN=VIM PE=1 SV=4 4.79 2235 - 854541 - - - 0.7254 - 1.621 0.19 - 134.2 1 2 1 0.0009 10 0 0 0 8.29E+06 1.88E+07 - - - 2.0687 0.9998 221125_WJC_METTL3_EV_vs_WT_F07.11757.11757.2 7.49E-07 24-Dec R.DQTPDENDQVIVK[136.11].L sp|Q9NZI8|IF2B1_HUMAN 1 1507.7246 1.82 99380 11757 2 1507.721749 754.8696 Insulin-like growth factor 2 mRNA-binding protein 1 OS=Homo sapiens OX=9606 GN=IGF2BP1 PE=1 SV=2 3.84 2235.4 - 501190 - - - -1.869 - 2.327 0.559 - 377 1 2 0 -0.0028 13 0 0 0 4.77E+07 2.63E+07 - - - 5.3365 0.9998 221125_WJC_METTL3_EV_vs_WT_F07.11760.11760.2 0.000117 13/22 K.LHGVNINVEASK[136.11].N "sp|Q9BWF3|RBM4_HUMAN,sp|Q9BQ04|RBM4B_HUMAN,tr|E9PM61|E9PM61_HUMAN,tr|D6R9K7|D6R9K7_HUMAN,tr|J3QRR5|J3QRR5_HUMAN,tr|E9PB51|E9PB51_HUMAN,tr|U3KQD5|U3KQD5_HUMAN,tr|E9PLB0|E9PLB0_HUMAN" 8 1287.7026 2.03 99383 11760 2 1287.704451 644.8586 RNA-binding protein 4 OS=Homo sapiens OX=9606 GN=RBM4 PE=1 SV=1 6.75 2235.8 - 317867 - - - 1.3986 - 2.382 0.455 - 532.2 1 2 0 0.0018 12 0 0 0 5.06E+06 2.49E+06 - - - 4.6848 0.9987 221125_WJC_METTL3_EV_vs_WT_F07.11764.11764.2 2.41E-05 22-Dec R.TNTPVKEDWNVR.L "sp|P78347|GTF2I_HUMAN,tr|A0A494C0Q7|A0A494C0Q7_HUMAN,tr|A0A494C1K3|A0A494C1K3_HUMAN" 3 1457.7263 1.52 99385 11764 2 1457.726084 729.8704 General transcription factor II-I OS=Homo sapiens OX=9606 GN=GTF2I PE=1 SV=2 5.74 2236.3 - 946561 - - - -0.1427 - 2.173 0.513 - 572.1 1 2 1 -0.0002 12 0 0 0 1.21E+08 7.99E+07 - - - 4.872 1 221125_WJC_METTL3_EV_vs_WT_F07.11768.11768.2 8.78E-10 15/28 K.TYDPSGDSTLPTC[160.03]SK.K sp|Q9Y2X3|NOP58_HUMAN 1 1627.7036 1.06 99389 11768 2 1627.704359 814.8591 Nucleolar protein 58 OS=Homo sapiens OX=9606 GN=NOP58 PE=1 SV=1 4.21 2236.8 - 902418 - - - 0.4866 - 2.932 0.709 - 609.2 1 2 0 0.0008 15 0 0 0 2.58E+07 2.43E+07 - - - 6.922 1 221125_WJC_METTL3_EV_vs_WT_F07.11769.11769.2 4.26E-05 13/28 K.TYDPSGDSTLPTC[160.03]SK[136.11].K sp|Q9Y2X3|NOP58_HUMAN 1 1635.7178 1.06 99390 11769 2 1635.71931 818.8662 Nucleolar protein 58 OS=Homo sapiens OX=9606 GN=NOP58 PE=1 SV=1 4.21 2236.9 - 790691 - - - 0.9433 - 2.519 0.642 - 411.4 1 2 0 0.0015 15 0 0 0 2.58E+07 2.43E+07 - - - 6.0537 0.9998 221125_WJC_METTL3_EV_vs_WT_F07.11775.11775.3 0.00992 13/32 R.EHLLDQLKR.K "sp|P52732|KIF11_HUMAN,tr|A0A7I2V3A9|A0A7I2V3A9_HUMAN" 2 1150.6459 4.39 99395 11775 3 1150.646513 384.5559 Kinesin-like protein KIF11 OS=Homo sapiens OX=9606 GN=KIF11 PE=1 SV=2 6.85 2237.7 - 1.01E+08 - - - 0.571 - 2.362 0.295 - 386.4 1 2 0 0.0007 9 0 0 0 1.03E+09 2.35E+08 - - - 4.4192 0.9999 221125_WJC_METTL3_EV_vs_WT_F07.11777.11777.3 3.05E-07 15/44 R.TNTPVK[136.11]EDWNVR[166.11].L "sp|P78347|GTF2I_HUMAN,tr|A0A494C0Q7|A0A494C0Q7_HUMAN,tr|A0A494C1K3|A0A494C1K3_HUMAN" 3 1475.7488 1.55 99397 11777 3 1475.749129 492.9235 General transcription factor II-I OS=Homo sapiens OX=9606 GN=GTF2I PE=1 SV=2 5.74 2237.8 - 3.12E+07 - - - 0.2487 - 2.997 0.572 - 495.7 1 2 1 0.0004 12 0 0 0 1.53E+09 9.86E+08 - - - 7.9595 0.9991 221125_WJC_METTL3_EV_vs_WT_F07.11778.11778.2 2.01E-08 14/22 R.TNTPVK[136.11]EDWNVR[166.11].L "sp|P78347|GTF2I_HUMAN,tr|A0A494C0Q7|A0A494C0Q7_HUMAN,tr|A0A494C1K3|A0A494C1K3_HUMAN" 3 1475.7488 1.52 99398 11778 2 1475.748775 738.8817 General transcription factor II-I OS=Homo sapiens OX=9606 GN=GTF2I PE=1 SV=2 5.74 2237.8 - 1.93E+06 - - - 0.0088 - 2.37 0.589 - 772.9 1 2 1 0 12 0 0 0 1.21E+08 7.99E+07 - - - 5.6618 1 221125_WJC_METTL3_EV_vs_WT_F07.11779.11779.3 8.02E-09 19/56 K.EQSGTIYLQHADEER.E "sp|P37198|NUP62_HUMAN,tr|M0QXN5|M0QXN5_HUMAN" 2 1774.8122 2.07 99399 11779 3 1774.812132 592.6113 Nuclear pore glycoprotein p62 OS=Homo sapiens OX=9606 GN=NUP62 PE=1 SV=3 4.4 2238 - 1.15E+06 - - - -0.0417 - 3.422 0.58 - 760.4 1 2 0 -0.0001 15 0 0 0 1.33E+08 6.44E+07 - - - 8.2165 1 221125_WJC_METTL3_EV_vs_WT_F07.11782.11782.3 5.25E-09 18/56 K.EQSGTIYLQHADEER[166.11].E "sp|P37198|NUP62_HUMAN,tr|M0QXN5|M0QXN5_HUMAN" 2 1784.8205 2.06 99402 11782 3 1784.826033 595.9474 Nuclear pore glycoprotein p62 OS=Homo sapiens OX=9606 GN=NUP62 PE=1 SV=3 4.4 2238.3 - 660958 - - - 3.1135 - 3.475 0.592 - 581 1 2 0 0.0056 15 0 0 0 1.33E+08 6.43E+07 - - - 8.3889 1 221125_WJC_METTL3_EV_vs_WT_F07.11783.11783.3 1.51E-06 13/64 R.VFQSSTSQEQVYNDC[160.03]AK.K sp|P33176|KINH_HUMAN 1 1989.8738 1.01 99403 11783 3 1989.873633 664.2986 Kinesin-1 heavy chain OS=Homo sapiens OX=9606 GN=KIF5B PE=1 SV=1 4.37 2238.5 - 487719 - - - -0.0945 - 2.452 0.577 - 165.3 1 2 0 -0.0002 17 0 0 0 5.33E+06 5.27E+06 - - - 7.2388 1 221125_WJC_METTL3_EV_vs_WT_F07.11784.11784.3 6.08E-05 Nov-64 R.VFQSSTSQEQVYNDC[160.03]AK[136.11].K sp|P33176|KINH_HUMAN 1 1997.888 1.01 99404 11784 3 1997.886431 666.97 Kinesin-1 heavy chain OS=Homo sapiens OX=9606 GN=KIF5B PE=1 SV=1 4.37 2238.6 - 459226 - - - -0.7958 - 2.01 0.536 - 143.4 1 2 0 -0.0016 17 0 0 0 5.33E+06 5.27E+06 - - - 6.2791 0.9999 221125_WJC_METTL3_EV_vs_WT_F07.11791.11791.3 2.61E-07 17/44 K.K[136.11]LEELEK[136.11]EEELR[166.11].T sp|Q9BZE4|GTPB4_HUMAN 1 1569.846 1.77 99410 11791 3 1569.84504 524.2893 GTP-binding protein 4 OS=Homo sapiens OX=9606 GN=GTPBP4 PE=1 SV=3 4.48 2239.3 - 1.69E+06 - - - -0.6262 - 3.248 0.546 - 447.1 1 2 1 -0.001 12 0 0 0 3.38E+07 1.91E+07 - - - 7.8924 0.9986 221125_WJC_METTL3_EV_vs_WT_F07.11793.11793.4 0.00837 13/66 K.K[136.11]LEELEK[136.11]EEELR[166.11].T sp|Q9BZE4|GTPB4_HUMAN 1 1569.846 1.73 99412 11793 4 1569.845442 393.4688 GTP-binding protein 4 OS=Homo sapiens OX=9606 GN=GTPBP4 PE=1 SV=3 4.48 2239.5 - 455828 - - - -0.3701 - 2.047 0.348 - 169.4 1 2 1 -0.0006 12 0 0 0 7.49E+06 4.34E+06 - - - 2.5259 1 221125_WJC_METTL3_EV_vs_WT_F07.11794.11794.2 1.72E-09 Nov-32 R.VFQSSTSQEQVYNDC[160.03]AK.K sp|P33176|KINH_HUMAN 1 1989.8738 1.16 99413 11794 2 1989.878686 995.9442 Kinesin-1 heavy chain OS=Homo sapiens OX=9606 GN=KIF5B PE=1 SV=1 4.37 2239.6 - 266503 - - - 2.4449 - 2.886 0.652 - 309 1 2 0 0.0049 17 0 0 0 3.29E+06 2.83E+06 - - - 6.4609 0.9851 221125_WJC_METTL3_EV_vs_WT_F07.11795.11795.2 0.000169 24-Jul F.SSSSSQLPLGQER[166.11].Q "sp|O75127|PTCD1_HUMAN,tr|G3V325|G3V325_HUMAN,tr|C9JGL8|C9JGL8_HUMAN,tr|C9JQN9|C9JQN9_HUMAN,tr|C9JWL7|C9JWL7_HUMAN" 5 1384.6822 0.25 99414 11795 2 1384.681994 693.3484 "Pentatricopeptide repeat-containing protein 1, mitochondrial OS=Homo sapiens OX=9606 GN=PTCD1 PE=1 SV=2" 5.72 2239.7 - 177918 - - - -0.143 - 1.715 0.454 - 113.2 1 1 0 -0.0002 13 0 0 0 1.29E+06 5.28E+06 - - - 3.7786 1 221125_WJC_METTL3_EV_vs_WT_F07.11797.11797.3 3.70E-05 20/40 R.SLHDALC[160.03]VVKR.V "sp|P17987|TCPA_HUMAN,tr|F5GZ03|F5GZ03_HUMAN,tr|F5H282|F5H282_HUMAN,tr|E7EQR6|E7EQR6_HUMAN,tr|E7ERF2|E7ERF2_HUMAN" 5 1296.6972 0.31 99415 11797 3 1296.69743 433.2397 T-complex protein 1 subunit alpha OS=Homo sapiens OX=9606 GN=TCP1 PE=1 SV=1 7.97 2240 - 1.13E+06 - - - 0.1465 - 3.35 0.57 - 639.7 1 2 0 0.0002 11 0 0 0 1.83E+07 5.96E+07 - - - 8.3293 0.9406 221125_WJC_METTL3_EV_vs_WT_F07.11799.11799.2 4.62E-07 16-Nov T.PVK[136.11]EDWNVR[166.11].L "sp|P78347|GTF2I_HUMAN,tr|A0A494C0Q7|A0A494C0Q7_HUMAN,tr|A0A494C1K3|A0A494C1K3_HUMAN" 3 1159.6105 1.59 99416 11799 2 1159.610183 580.8125 General transcription factor II-I OS=Homo sapiens OX=9606 GN=GTF2I PE=1 SV=2 6.49 2240.2 - 825048 - - - -0.2535 - 2.155 0.555 - 468.4 1 1 1 -0.0003 9 0 0 0 2.33E+07 1.46E+07 - - - 5.3614 1 221125_WJC_METTL3_EV_vs_WT_F07.11806.11806.2 1.88E-07 Nov-32 R.VFQSSTSQEQVYNDC[160.03]AK[136.11].K sp|P33176|KINH_HUMAN 1 1997.888 1.16 99423 11806 2 1997.8884 999.9513 Kinesin-1 heavy chain OS=Homo sapiens OX=9606 GN=KIF5B PE=1 SV=1 4.37 2240.9 - 228031 - - - 0.1897 - 2.634 0.643 - 325.9 1 2 0 0.0004 17 0 0 0 3.29E+06 2.83E+06 - - - 6.1712 0.9998 221125_WJC_METTL3_EV_vs_WT_F07.11809.11809.3 0.00135 Nov-48 K.SEPKPGLPEDLQK.L "sp|Q9BQ75|CMS1_HUMAN,tr|C9J384|C9J384_HUMAN" 2 1436.7511 0.95 99424 11809 3 1436.753531 479.9243 Protein CMSS1 OS=Homo sapiens OX=9606 GN=CMSS1 PE=1 SV=2 4.68 2241.3 - 1.67E+06 - - - 1.6857 - 2.077 0.389 - 101.9 1 2 0 0.0024 13 0 0 0 3.81E+07 3.99E+07 - - - 4.858 0.9999 221125_WJC_METTL3_EV_vs_WT_F07.11817.11817.3 1.93E-07 15/44 R.TNTPVKEDWNVR.L "sp|P78347|GTF2I_HUMAN,tr|A0A494C0Q7|A0A494C0Q7_HUMAN,tr|A0A494C1K3|A0A494C1K3_HUMAN" 3 1457.7263 1.55 99430 11817 3 1457.728166 486.916 General transcription factor II-I OS=Homo sapiens OX=9606 GN=GTF2I PE=1 SV=2 5.74 2242.3 - 1.28E+08 - - - 1.2856 - 3.033 0.546 - 577 1 2 1 0.0019 12 0 0 0 1.53E+09 9.86E+08 - - - 7.7024 0.9261 221125_WJC_METTL3_EV_vs_WT_F07.11818.11818.2 1.16E-08 13/20 T.NTPVKEDWNVR.L "sp|P78347|GTF2I_HUMAN,tr|A0A494C0Q7|A0A494C0Q7_HUMAN,tr|A0A494C1K3|A0A494C1K3_HUMAN" 3 1356.6786 7.2 99431 11818 2 1356.676768 679.3466 General transcription factor II-I OS=Homo sapiens OX=9606 GN=GTF2I PE=1 SV=2 6.07 2242.4 - 936578 - - - -1.3599 - 2.407 0.577 - 714.9 1 1 1 -0.0018 11 0 0 0 1.31E+07 1.82E+06 - - - 5.6784 0.9999 221125_WJC_METTL3_EV_vs_WT_F07.11822.11822.2 3.97E-08 28-Dec K.EQSGTIYLQHADEER.E "sp|P37198|NUP62_HUMAN,tr|M0QXN5|M0QXN5_HUMAN" 2 1774.8122 4.72 99435 11822 2 1774.812086 888.4134 Nuclear pore glycoprotein p62 OS=Homo sapiens OX=9606 GN=NUP62 PE=1 SV=3 4.4 2242.9 - 292825 - - - -0.0676 - 2.71 0.466 - 572.3 1 2 0 -0.0001 15 0 0 0 4.27E+06 9.04E+05 - - - 4.9339 1 221125_WJC_METTL3_EV_vs_WT_F07.11828.11828.3 1.94E-08 18/60 R.SSGPYGGGGQYFAKPR.N "sp|P09651|ROA1_HUMAN,tr|A0A7I2YQX9|A0A7I2YQX9_HUMAN,tr|A0A7I2V5N7|A0A7I2V5N7_HUMAN,tr|A0A7I2V661|A0A7I2V661_HUMAN,tr|A0A7I2V520|A0A7I2V520_HUMAN,tr|A0A7I2V2F1|A0A7I2V2F1_HUMAN,tr|A0A7I2V497|A0A7I2V497_HUMAN,tr|A0A7I2V3K5|A0A7I2V3K5_HUMAN,tr|A0A7I2V2M7|A0A7I2V2M7_HUMAN,tr|A0A7I2V4P7|A0A7I2V4P7_HUMAN,tr|A0A7I2V5P1|A0A7I2V5P1_HUMAN,tr|A0A7I2V334|A0A7I2V334_HUMAN,tr|A0A7I2V4E2|A0A7I2V4E2_HUMAN,tr|A0A7I2V4F8|A0A7I2V4F8_HUMAN,tr|A0A7I2V3R8|A0A7I2V3R8_HUMAN,tr|F8W6I7|F8W6I7_HUMAN,tr|A0A7I2V666|A0A7I2V666_HUMAN,tr|A0A7I2V2Q7|A0A7I2V2Q7_HUMAN,tr|A0A7I2V459|A0A7I2V459_HUMAN,tr|A0A7I2YQY2|A0A7I2YQY2_HUMAN,tr|H0YH80|H0YH80_HUMAN,tr|A0A7I2V3W0|A0A7I2V3W0_HUMAN,tr|A0A7I2V3U8|A0A7I2V3U8_HUMAN,tr|A0A7I2V2R4|A0A7I2V2R4_HUMAN,tr|A0A7I2V2X1|A0A7I2V2X1_HUMAN,tr|A0A7I2V453|A0A7I2V453_HUMAN,tr|A0A7I2V360|A0A7I2V360_HUMAN" 27 1627.7743 1.26 99439 11828 3 1627.767275 543.5987 Heterogeneous nuclear ribonucleoprotein A1 OS=Homo sapiens OX=9606 GN=HNRNPA1 PE=1 SV=5 9.7 2243.7 - 1.30E+06 - - - -4.3188 - 3.313 0.641 - 454.7 1 2 0 -0.007 16 0 0 0 3.09E+09 2.46E+09 - - - 8.7581 1 221125_WJC_METTL3_EV_vs_WT_F07.11830.11830.4 6.12E-07 13/78 R.VQPGHC[160.03]YHLYNGLR[166.11].A "sp|Q9H2U1|DHX36_HUMAN,tr|E7EWK3|E7EWK3_HUMAN,tr|H7C5F5|H7C5F5_HUMAN" 3 1722.8288 1.38 99441 11830 4 1722.829132 431.7145 ATP-dependent DNA\RNA helicase DHX36 OS=Homo sapiens OX=9606 GN=DHX36 PE=1 SV=2 8.19 2243.9 - 490398 - - - 0.1852 - 2.357 0.524 - 153.6 1 2 0 0.0003 14 0 0 0 7.34E+06 5.33E+06 - - - 4.0988 0.9999 221125_WJC_METTL3_EV_vs_WT_F07.11832.11832.4 3.43E-05 Nov-78 R.VQPGHC[160.03]YHLYNGLR.A "sp|Q9H2U1|DHX36_HUMAN,tr|E7EWK3|E7EWK3_HUMAN,tr|H7C5F5|H7C5F5_HUMAN" 3 1712.8205 0.73 99443 11832 4 1712.816626 429.2124 ATP-dependent DNA\RNA helicase DHX36 OS=Homo sapiens OX=9606 GN=DHX36 PE=1 SV=2 8.19 2244.2 - 386147 - - - -2.2869 - 2.259 0.478 - 81.3 1 2 0 -0.0039 14 0 0 0 3.65E+06 5.02E+06 - - - 3.682 0.9999 221125_WJC_METTL3_EV_vs_WT_F07.11833.11833.3 2.87E-05 Oct-60 K.STQPISSVGK[136.11]PASVIK[136.11].N "sp|Q7Z6E9|RBBP6_HUMAN,tr|A0A2R8Y880|A0A2R8Y880_HUMAN" 2 1613.9323 2.62 99444 11833 3 1613.929988 538.9847 E3 ubiquitin-protein ligase RBBP6 OS=Homo sapiens OX=9606 GN=RBBP6 PE=1 SV=1 10 2244.3 - 418686 - - - -1.4462 - 2.168 0.423 - 94.6 1 2 0 -0.0023 16 0 0 0 1.42E+07 5.42E+06 - - - 5.2409 0.9999 221125_WJC_METTL3_EV_vs_WT_F07.11838.11838.4 0.000191 18/78 K.VLAQYYTVTDEHHR[166.11].S sp|Q9NX58|LYAR_HUMAN 1 1740.8459 0.58 99447 11838 4 1740.847562 436.2188 Cell growth-regulating nucleolar protein OS=Homo sapiens OX=9606 GN=LYAR PE=1 SV=2 5.99 2245 - 864784 - - - 0.953 - 2.815 0.433 - 237.3 1 2 0 0.0017 14 0 0 0 1.42E+07 2.45E+07 - - - 3.371 1 221125_WJC_METTL3_EV_vs_WT_F07.11840.11840.2 6.87E-09 24-Dec R.SEDQNC[160.03]VPPLQER.K sp|Q5JSZ5|PRC2B_HUMAN 1 1570.7046 1.91 99449 11840 2 1570.708278 786.3596 Protein PRRC2B OS=Homo sapiens OX=9606 GN=PRRC2B PE=1 SV=2 4.14 2245.2 - 502566 - - - 2.3607 - 2.555 0.658 - 284 1 2 0 0.0037 13 0 0 0 3.70E+07 1.94E+07 - - - 6.3074 0.9999 221125_WJC_METTL3_EV_vs_WT_F07.11841.11841.2 5.46E-06 28-Nov R.SAQGSSSPVPSMVQK.S "sp|P35658|NU214_HUMAN,tr|A0A0A0MSW3|A0A0A0MSW3_HUMAN,tr|A0A494BZU9|A0A494BZU9_HUMAN,tr|A0A494C1F2|A0A494C1F2_HUMAN" 4 1488.7242 1.91 99450 11841 2 1488.725132 745.3694 Nuclear pore complex protein Nup214 OS=Homo sapiens OX=9606 GN=NUP214 PE=1 SV=2 8.47 2245.4 - 453201 - - - 0.5972 - 2.548 0.586 - 274.6 1 2 0 0.0009 15 0 0 0 7.99E+07 4.19E+07 - - - 5.6684 1 221125_WJC_METTL3_EV_vs_WT_F07.11843.11843.2 2.22E-08 24-Dec R.SEDQNC[160.03]VPPLQER[166.11].K sp|Q5JSZ5|PRC2B_HUMAN 1 1580.7128 1.93 99452 11843 2 1580.714216 791.3637 Protein PRRC2B OS=Homo sapiens OX=9606 GN=PRRC2B PE=1 SV=2 4.14 2245.6 - 372260 - - - 0.8705 - 2.553 0.684 - 295.9 1 2 0 0.0014 13 0 0 0 3.55E+07 1.84E+07 - - - 6.4981 0.9999 221125_WJC_METTL3_EV_vs_WT_F07.11844.11844.4 2.12E-05 15/78 K.VLAQYYTVTDEHHR.S sp|Q9NX58|LYAR_HUMAN 1 1730.8376 0.58 99453 11844 4 1730.839852 433.7167 Cell growth-regulating nucleolar protein OS=Homo sapiens OX=9606 GN=LYAR PE=1 SV=2 5.99 2245.7 - 496640 - - - 1.282 - 2.71 0.467 - 144.7 1 2 0 0.0022 14 0 0 0 1.42E+07 2.45E+07 - - - 3.653 0.9985 221125_WJC_METTL3_EV_vs_WT_F07.11845.11845.3 0.00626 14/52 R.IQK[136.11]EEEEILMANK[136.11]R[166.11].C "sp|Q4VCS5|AMOT_HUMAN,tr|A6NP16|A6NP16_HUMAN,tr|E7ERM3|E7ERM3_HUMAN" 3 1755.9399 2.16 99454 11845 3 1755.947045 586.3206 Angiomotin OS=Homo sapiens OX=9606 GN=AMOT PE=1 SV=1 4.95 2245.9 - 240987 - - - 4.0463 - 2.509 0.465 - 222.2 1 2 1 0.0071 14 0 0 0 8.03E+06 3.72E+06 - - - 6.1669 1 221125_WJC_METTL3_EV_vs_WT_F07.11849.11849.3 1.26E-09 18/60 R.SSGPYGGGGQYFAK[136.11]PR[166.11].N "sp|P09651|ROA1_HUMAN,tr|A0A7I2YQX9|A0A7I2YQX9_HUMAN,tr|A0A7I2V5N7|A0A7I2V5N7_HUMAN,tr|A0A7I2V661|A0A7I2V661_HUMAN,tr|A0A7I2V520|A0A7I2V520_HUMAN,tr|A0A7I2V2F1|A0A7I2V2F1_HUMAN,tr|A0A7I2V497|A0A7I2V497_HUMAN,tr|A0A7I2V3K5|A0A7I2V3K5_HUMAN,tr|A0A7I2V2M7|A0A7I2V2M7_HUMAN,tr|A0A7I2V4P7|A0A7I2V4P7_HUMAN,tr|A0A7I2V5P1|A0A7I2V5P1_HUMAN,tr|A0A7I2V334|A0A7I2V334_HUMAN,tr|A0A7I2V4E2|A0A7I2V4E2_HUMAN,tr|A0A7I2V4F8|A0A7I2V4F8_HUMAN,tr|A0A7I2V3R8|A0A7I2V3R8_HUMAN,tr|F8W6I7|F8W6I7_HUMAN,tr|A0A7I2V666|A0A7I2V666_HUMAN,tr|A0A7I2V2Q7|A0A7I2V2Q7_HUMAN,tr|A0A7I2V459|A0A7I2V459_HUMAN,tr|A0A7I2YQY2|A0A7I2YQY2_HUMAN,tr|H0YH80|H0YH80_HUMAN,tr|A0A7I2V3W0|A0A7I2V3W0_HUMAN,tr|A0A7I2V3U8|A0A7I2V3U8_HUMAN,tr|A0A7I2V2R4|A0A7I2V2R4_HUMAN,tr|A0A7I2V2X1|A0A7I2V2X1_HUMAN,tr|A0A7I2V453|A0A7I2V453_HUMAN,tr|A0A7I2V360|A0A7I2V360_HUMAN" 27 1645.7968 1.26 99456 11849 3 1645.797662 549.6062 Heterogeneous nuclear ribonucleoprotein A1 OS=Homo sapiens OX=9606 GN=HNRNPA1 PE=1 SV=5 9.7 2246.4 - 5.24E+06 - - - 0.5389 - 3.451 0.651 - 546.3 1 2 0 0.0009 16 0 0 0 3.09E+09 2.46E+09 - - - 8.976 1 221125_WJC_METTL3_EV_vs_WT_F07.11850.11850.3 1.03E-07 15/52 K.VLAQYYTVTDEHHR[166.11].S sp|Q9NX58|LYAR_HUMAN 1 1740.8459 0.43 99457 11850 3 1740.845831 581.2892 Cell growth-regulating nucleolar protein OS=Homo sapiens OX=9606 GN=LYAR PE=1 SV=2 5.99 2246.5 - 1.21E+06 - - - -0.0414 - 2.932 0.523 - 320.5 1 2 0 -0.0001 14 0 0 0 1.22E+07 2.84E+07 - - - 7.2296 1 221125_WJC_METTL3_EV_vs_WT_F07.11851.11851.3 8.24E-08 Dec-48 R.AHSSMVGVNLPQK[136.11].A sp|P00558|PGK1_HUMAN 1 1374.7169 0.96 99458 11851 3 1374.717753 459.2462 Phosphoglycerate kinase 1 OS=Homo sapiens OX=9606 GN=PGK1 PE=1 SV=3 8.8 2246.5 - 1.18E+06 - - - 0.6067 - 2.417 0.572 - 213.6 1 2 0 0.0008 13 0 0 0 5.84E+06 6.07E+06 - - - 7.3098 1 221125_WJC_METTL3_EV_vs_WT_F07.11856.11856.2 8.40E-06 28-Dec R.EATSSTSNFSSLSSK[136.11].F sp|Q9P2D1|CHD7_HUMAN 1 1539.7144 1.32 99463 11856 2 1539.714103 770.8645 Chromodomain-helicase-DNA-binding protein 7 OS=Homo sapiens OX=9606 GN=CHD7 PE=1 SV=3 6.1 2247.1 - 408942 - - - -0.1903 - 2.83 0.584 - 548.3 1 2 0 -0.0003 15 0 0 0 5.00E+07 3.78E+07 - - - 5.9119 0.9997 221125_WJC_METTL3_EV_vs_WT_F07.11857.11857.3 0.0168 Oct-48 R.SEDQNC[160.03]VPPLQER.K sp|Q5JSZ5|PRC2B_HUMAN 1 1570.7046 4.17 99464 11857 3 1570.708425 524.5755 Protein PRRC2B OS=Homo sapiens OX=9606 GN=PRRC2B PE=1 SV=2 4.14 2247.3 - 325017 - - - 2.4543 - 1.822 0.449 - 129.9 1 2 0 0.0039 13 0 0 0 3.21E+07 7.70E+06 - - - 5.1714 0.9998 221125_WJC_METTL3_EV_vs_WT_F07.11864.11864.4 0.000144 16/72 K.YK[136.11]R[166.11]PGYGAYDAFK[136.11].H "sp|P05198|IF2A_HUMAN,tr|H0YJS4|H0YJS4_HUMAN,tr|G3V4T5|G3V4T5_HUMAN" 3 1560.7935 0.77 99470 11864 4 1560.792106 391.2057 Eukaryotic translation initiation factor 2 subunit 1 OS=Homo sapiens OX=9606 GN=EIF2S1 PE=1 SV=3 9.4 2248.1 - 1.07E+06 - - - -0.9149 - 2.395 0.481 - 121.7 1 2 1 -0.0014 13 0 0 0 5.87E+06 7.65E+06 - - - 3.7361 1 221125_WJC_METTL3_EV_vs_WT_F07.11865.11865.3 7.94E-08 21/52 K.VLAQYYTVTDEHHR.S sp|Q9NX58|LYAR_HUMAN 1 1730.8376 0.44 99471 11865 3 1730.837546 577.9532 Cell growth-regulating nucleolar protein OS=Homo sapiens OX=9606 GN=LYAR PE=1 SV=2 5.99 2248.2 - 1.04E+06 - - - -0.0503 - 3.564 0.559 - 753.6 1 2 0 -0.0001 14 0 0 0 1.22E+07 2.76E+07 - - - 8.1497 1 221125_WJC_METTL3_EV_vs_WT_F07.11867.11867.2 5.80E-08 15/28 R.EATSSTSNFSSLSSK.F sp|Q9P2D1|CHD7_HUMAN 1 1531.7002 1.32 99473 11867 2 1531.699477 766.8574 Chromodomain-helicase-DNA-binding protein 7 OS=Homo sapiens OX=9606 GN=CHD7 PE=1 SV=3 6.1 2248.5 - 928307 - - - -0.4694 - 3.173 0.651 - 1078.6 1 2 0 -0.0007 15 0 0 0 5.00E+07 3.78E+07 - - - 6.6879 1 221125_WJC_METTL3_EV_vs_WT_F07.11868.11868.2 2.04E-08 14/30 R.SDSPVPTAPTSGGPK[136.11]P.S "sp|Q86U44|MTA70_HUMAN,tr|B4E349|B4E349_HUMAN,tr|F5H6D8|F5H6D8_HUMAN,tr|B4DTN4|B4DTN4_HUMAN" 4 1501.7504 0.24 99474 11868 2 1501.750207 751.8825 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 5.55 2248.6 - 747786 - - - -0.1205 - 2.701 0.639 - 377.4 1 1 0 -0.0002 16 0 0 0 6.82E+06 2.87E+07 - - - 6.2035 0.9999 221125_WJC_METTL3_EV_vs_WT_F07.11870.11870.3 0.00355 13/44 R.QGSFSEDVISHK.G "sp|Q9UPN3|MACF1_HUMAN,tr|H3BQK9|H3BQK9_HUMAN,tr|A0A7P0MQR8|A0A7P0MQR8_HUMAN,tr|E9PNZ4|E9PNZ4_HUMAN,tr|H0Y390|H0Y390_HUMAN,tr|H3BPE1|H3BPE1_HUMAN,tr|A0A590UJG2|A0A590UJG2_HUMAN" 7 1332.631 1.58 99476 11870 3 1332.629758 445.2176 "Microtubule-actin cross-linking factor 1, isoforms 1\2\3\5 OS=Homo sapiens OX=9606 GN=MACF1 PE=1 SV=4" 5.32 2248.9 - 639866 - - - -0.9275 - 2.085 0.396 - 130.6 1 2 0 -0.0012 12 0 0 0 5.30E+06 3.36E+06 - - - 4.9913 1 221125_WJC_METTL3_EV_vs_WT_F07.11871.11871.3 2.93E-05 13/52 R.KLDPGSEETQTLVR.E sp|P26641|EF1G_HUMAN 1 1571.8155 1.1 99477 11871 3 1571.816551 524.9458 Elongation factor 1-gamma OS=Homo sapiens OX=9606 GN=EEF1G PE=1 SV=3 4.68 2249 - 585884 - - - 0.668 - 2.625 0.459 - 300 1 2 0 0.0011 14 0 0 0 1.26E+07 1.14E+07 - - - 6.2218 0.9965 221125_WJC_METTL3_EV_vs_WT_F07.11872.11872.4 0.0166 13/78 R.IQK[136.11]EEEEILMANK[136.11]R[166.11].C "sp|Q4VCS5|AMOT_HUMAN,tr|A6NP16|A6NP16_HUMAN,tr|E7ERM3|E7ERM3_HUMAN" 3 1755.9399 2.34 99478 11872 4 1755.943014 439.9923 Angiomotin OS=Homo sapiens OX=9606 GN=AMOT PE=1 SV=1 4.95 2249.1 - 449774 - - - 1.7506 - 1.971 0.318 - 174 1 2 1 0.0031 14 0 0 0 3.47E+06 1.48E+06 - - - 2.24 0.9891 221125_WJC_METTL3_EV_vs_WT_F07.11875.11875.3 0.0998 Sep-44 R.QGSFSEDVISHK[136.11].G "sp|Q9UPN3|MACF1_HUMAN,tr|H3BQK9|H3BQK9_HUMAN,tr|A0A7P0MQR8|A0A7P0MQR8_HUMAN,tr|E9PNZ4|E9PNZ4_HUMAN,tr|H0Y390|H0Y390_HUMAN,tr|H3BPE1|H3BPE1_HUMAN,tr|A0A590UJG2|A0A590UJG2_HUMAN" 7 1340.6452 1.58 99481 11875 3 1340.642743 447.889 "Microtubule-actin cross-linking factor 1, isoforms 1\2\3\5 OS=Homo sapiens OX=9606 GN=MACF1 PE=1 SV=4" 5.32 2249.5 - 279283 - - - -1.8282 - 1.483 0.216 - 82 1 2 0 -0.0025 12 0 0 0 5.30E+06 3.36E+06 - - - 2.0398 1 221125_WJC_METTL3_EV_vs_WT_F07.11876.11876.2 2.67E-10 30-Dec R.SSGPYGGGGQYFAK[136.11]PR[166.11].N "sp|P09651|ROA1_HUMAN,tr|A0A7I2YQX9|A0A7I2YQX9_HUMAN,tr|A0A7I2V5N7|A0A7I2V5N7_HUMAN,tr|A0A7I2V661|A0A7I2V661_HUMAN,tr|A0A7I2V520|A0A7I2V520_HUMAN,tr|A0A7I2V2F1|A0A7I2V2F1_HUMAN,tr|A0A7I2V497|A0A7I2V497_HUMAN,tr|A0A7I2V3K5|A0A7I2V3K5_HUMAN,tr|A0A7I2V2M7|A0A7I2V2M7_HUMAN,tr|A0A7I2V4P7|A0A7I2V4P7_HUMAN,tr|A0A7I2V5P1|A0A7I2V5P1_HUMAN,tr|A0A7I2V334|A0A7I2V334_HUMAN,tr|A0A7I2V4E2|A0A7I2V4E2_HUMAN,tr|A0A7I2V4F8|A0A7I2V4F8_HUMAN,tr|A0A7I2V3R8|A0A7I2V3R8_HUMAN,tr|F8W6I7|F8W6I7_HUMAN,tr|A0A7I2V666|A0A7I2V666_HUMAN,tr|A0A7I2V2Q7|A0A7I2V2Q7_HUMAN,tr|A0A7I2V459|A0A7I2V459_HUMAN,tr|A0A7I2YQY2|A0A7I2YQY2_HUMAN,tr|H0YH80|H0YH80_HUMAN,tr|A0A7I2V3W0|A0A7I2V3W0_HUMAN,tr|A0A7I2V3U8|A0A7I2V3U8_HUMAN,tr|A0A7I2V2R4|A0A7I2V2R4_HUMAN,tr|A0A7I2V2X1|A0A7I2V2X1_HUMAN,tr|A0A7I2V453|A0A7I2V453_HUMAN,tr|A0A7I2V360|A0A7I2V360_HUMAN" 27 1645.7968 1.3 99482 11876 2 1645.795284 823.9057 Heterogeneous nuclear ribonucleoprotein A1 OS=Homo sapiens OX=9606 GN=HNRNPA1 PE=1 SV=5 9.7 2249.6 - 275152 - - - -0.9059 - 2.565 0.678 - 383.1 1 2 0 -0.0015 16 0 0 0 1.37E+08 1.05E+08 - - - 6.3641 1 221125_WJC_METTL3_EV_vs_WT_F07.11879.11879.3 2.05E-08 16/52 R.QDPQSTAAATVLK[136.11]R[166.11].A "sp|Q8WV92|MITD1_HUMAN,tr|F8WED5|F8WED5_HUMAN,tr|B8ZZL5|B8ZZL5_HUMAN,tr|A0A1W2PP14|A0A1W2PP14_HUMAN" 4 1502.8172 1.28 99484 11879 3 1502.815383 501.9463 MIT domain-containing protein 1 OS=Homo sapiens OX=9606 GN=MITD1 PE=1 SV=1 8.75 2250 - 525127 - - - -1.1931 - 2.816 0.609 - 281.5 1 2 0 -0.0018 14 0 0 0 4.92E+07 3.84E+07 - - - 8.0806 1 221125_WJC_METTL3_EV_vs_WT_F07.11880.11880.3 9.72E-10 13/52 R.K[136.11]LDPGSEETQTLVR[166.11].E sp|P26641|EF1G_HUMAN 1 1589.838 1.1 99485 11880 3 1589.83807 530.9533 Elongation factor 1-gamma OS=Homo sapiens OX=9606 GN=EEF1G PE=1 SV=3 4.68 2250.1 - 1.28E+06 - - - 0.0623 - 3.131 0.569 - 288.6 1 2 0 0.0001 14 0 0 0 1.26E+07 1.14E+07 - - - 7.9169 0.9999 221125_WJC_METTL3_EV_vs_WT_F07.11881.11881.3 3.79E-07 13/48 K.YKRPGYGAYDAFK.H "sp|P05198|IF2A_HUMAN,tr|H0YJS4|H0YJS4_HUMAN,tr|G3V4T5|G3V4T5_HUMAN" 3 1534.7569 0.51 99486 11881 3 1534.755735 512.5929 Eukaryotic translation initiation factor 2 subunit 1 OS=Homo sapiens OX=9606 GN=EIF2S1 PE=1 SV=3 9.4 2250.1 - 3.36E+06 - - - -0.7356 - 2.983 0.574 - 131.6 1 2 1 -0.0011 13 0 0 0 1.53E+07 3.00E+07 - - - 7.9025 0.999 221125_WJC_METTL3_EV_vs_WT_F07.11883.11883.4 0.00383 Nov-72 K.YKRPGYGAYDAFK.H "sp|P05198|IF2A_HUMAN,tr|H0YJS4|H0YJS4_HUMAN,tr|G3V4T5|G3V4T5_HUMAN" 3 1534.7569 0.58 99488 11883 4 1534.756002 384.6965 Eukaryotic translation initiation factor 2 subunit 1 OS=Homo sapiens OX=9606 GN=EIF2S1 PE=1 SV=3 9.4 2250.3 - 1.28E+06 - - - -0.5617 - 1.943 0.368 - 59.3 1 2 1 -0.0009 13 0 0 0 5.94E+06 1.02E+07 - - - 2.6751 1 221125_WJC_METTL3_EV_vs_WT_F07.11885.11885.2 3.83E-09 15/28 R.SAQGSSSPVPSMVQK[136.11].S "sp|P35658|NU214_HUMAN,tr|A0A0A0MSW3|A0A0A0MSW3_HUMAN,tr|A0A494BZU9|A0A494BZU9_HUMAN,tr|A0A494C1F2|A0A494C1F2_HUMAN" 4 1496.7384 1.91 99490 11885 2 1496.737814 749.3765 Nuclear pore complex protein Nup214 OS=Homo sapiens OX=9606 GN=NUP214 PE=1 SV=2 8.47 2250.5 - 813120 - - - -0.4202 - 3.001 0.646 - 548.9 1 2 0 -0.0006 15 0 0 0 7.99E+07 4.19E+07 - - - 6.514 1 221125_WJC_METTL3_EV_vs_WT_F07.11887.11887.2 8.05E-14 18/30 R.SSGPYGGGGQYFAKPR.N "sp|P09651|ROA1_HUMAN,tr|A0A7I2YQX9|A0A7I2YQX9_HUMAN,tr|A0A7I2V5N7|A0A7I2V5N7_HUMAN,tr|A0A7I2V661|A0A7I2V661_HUMAN,tr|A0A7I2V520|A0A7I2V520_HUMAN,tr|A0A7I2V2F1|A0A7I2V2F1_HUMAN,tr|A0A7I2V497|A0A7I2V497_HUMAN,tr|A0A7I2V3K5|A0A7I2V3K5_HUMAN,tr|A0A7I2V2M7|A0A7I2V2M7_HUMAN,tr|A0A7I2V4P7|A0A7I2V4P7_HUMAN,tr|A0A7I2V5P1|A0A7I2V5P1_HUMAN,tr|A0A7I2V334|A0A7I2V334_HUMAN,tr|A0A7I2V4E2|A0A7I2V4E2_HUMAN,tr|A0A7I2V4F8|A0A7I2V4F8_HUMAN,tr|A0A7I2V3R8|A0A7I2V3R8_HUMAN,tr|F8W6I7|F8W6I7_HUMAN,tr|A0A7I2V666|A0A7I2V666_HUMAN,tr|A0A7I2V2Q7|A0A7I2V2Q7_HUMAN,tr|A0A7I2V459|A0A7I2V459_HUMAN,tr|A0A7I2YQY2|A0A7I2YQY2_HUMAN,tr|H0YH80|H0YH80_HUMAN,tr|A0A7I2V3W0|A0A7I2V3W0_HUMAN,tr|A0A7I2V3U8|A0A7I2V3U8_HUMAN,tr|A0A7I2V2R4|A0A7I2V2R4_HUMAN,tr|A0A7I2V2X1|A0A7I2V2X1_HUMAN,tr|A0A7I2V453|A0A7I2V453_HUMAN,tr|A0A7I2V360|A0A7I2V360_HUMAN" 27 1627.7743 1.3 99492 11887 2 1627.775226 814.8944 Heterogeneous nuclear ribonucleoprotein A1 OS=Homo sapiens OX=9606 GN=HNRNPA1 PE=1 SV=5 9.7 2250.7 - 581060 - - - 0.5658 - 3.139 0.703 - 992 1 2 0 0.0009 16 0 0 0 1.37E+08 1.05E+08 - - - 7.0454 1 221125_WJC_METTL3_EV_vs_WT_F07.11896.11896.3 0.000116 13/48 R.AHSSMVGVNLPQK.A sp|P00558|PGK1_HUMAN 1 1366.7027 0.7 99500 11896 3 1366.703353 456.5748 Phosphoglycerate kinase 1 OS=Homo sapiens OX=9606 GN=PGK1 PE=1 SV=3 8.8 2251.9 - 1.01E+06 - - - 0.4639 - 2.264 0.552 - 235.8 1 2 0 0.0006 13 0 0 0 1.35E+07 1.93E+07 - - - 6.9096 0.9997 221125_WJC_METTL3_EV_vs_WT_F07.11897.11897.3 0.000569 Nov-56 R.EALQQQHSVQVDQLR.M "sp|Q9Y6K9|NEMO_HUMAN,tr|C9JN51|C9JN51_HUMAN,tr|A0A087X1B1|A0A087X1B1_HUMAN,tr|C9J2V2|C9J2V2_HUMAN,tr|A0A087WUW6|A0A087WUW6_HUMAN,tr|A0A087WV30|A0A087WV30_HUMAN,tr|A0A087X0G7|A0A087X0G7_HUMAN" 7 1777.9071 0.5 99501 11897 3 1777.911444 593.643 NF-kappa-B essential modulator OS=Homo sapiens OX=9606 GN=IKBKG PE=1 SV=2 5.32 2252 - 720774 - - - 2.4377 - 2.47 0.378 - 201.9 1 2 0 0.0043 15 0 0 0 4.08E+06 8.15E+06 - - - 5.1126 1 221125_WJC_METTL3_EV_vs_WT_F07.11904.11904.3 9.58E-08 Nov-56 R.IAEQEHTQEDLQQLR.S "sp|Q9UPN3|MACF1_HUMAN,tr|H3BQK9|H3BQK9_HUMAN,tr|A0A7P0MQR8|A0A7P0MQR8_HUMAN,tr|E9PNZ4|E9PNZ4_HUMAN,tr|H0Y390|H0Y390_HUMAN,tr|E9PLY5|E9PLY5_HUMAN,tr|H3BPE1|H3BPE1_HUMAN,tr|A0A669KBB0|A0A669KBB0_HUMAN,tr|A0A590UJG2|A0A590UJG2_HUMAN,tr|A0A5F9ZGX0|A0A5F9ZGX0_HUMAN" 10 1836.8966 2.18 99506 11904 3 1836.897185 613.3061 "Microtubule-actin cross-linking factor 1, isoforms 1\2\3\5 OS=Homo sapiens OX=9606 GN=MACF1 PE=1 SV=4" 4.4 2252.9 - 1.24E+06 - - - 0.3157 - 2.941 0.546 - 200 1 2 0 0.0006 15 0 0 0 1.82E+07 8.33E+06 - - - 7.4421 1 221125_WJC_METTL3_EV_vs_WT_F07.11905.11905.3 1.68E-06 14/36 R.K[136.11]MR[166.11]PFEGFQR[166.11].K "sp|Q9BUJ2|HNRL1_HUMAN,tr|A0A0A0MRA5|A0A0A0MRA5_HUMAN,tr|M0R3F1|M0R3F1_HUMAN,tr|B7Z4B8|B7Z4B8_HUMAN" 4 1322.6912 2 99507 11905 3 1322.690909 441.9043 Heterogeneous nuclear ribonucleoprotein U-like protein 1 OS=Homo sapiens OX=9606 GN=HNRNPUL1 PE=1 SV=2 10.84 2253 - 834217 - - - -0.2208 - 2.567 0.474 - 364.2 1 2 0 -0.0003 10 0 0 0 1.24E+07 6.20E+06 - - - 6.5778 0.9999 221125_WJC_METTL3_EV_vs_WT_F07.11908.11908.3 2.99E-06 Dec-56 R.NGLTHQLGGLSQGSR.N "sp|Q8N5F7|NKAP_HUMAN,tr|A0A494C050|A0A494C050_HUMAN" 2 1523.7805 0.55 99510 11908 3 1523.780571 508.9341 NF-kappa-B-activating protein OS=Homo sapiens OX=9606 GN=NKAP PE=1 SV=1 9.76 2253.3 - 714845 - - - 0.0774 - 2.319 0.438 - 178.5 1 2 0 0.0001 15 0 0 0 1.84E+07 3.37E+07 - - - 5.6181 0.914 221125_WJC_METTL3_EV_vs_WT_F07.11910.11910.3 0.0957 Jul-32 R.LSC[160.03]C[160.03]LYKPR.M sp|Q9Y6X9|MORC2_HUMAN 1 1195.5842 14.67 99512 11910 3 1195.580728 399.5353 ATPase MORC2 OS=Homo sapiens OX=9606 GN=MORC2 PE=1 SV=2 8.9 2253.5 - 305244 - - - -2.8915 - 1.36 0.158 - 72.1 1 2 0 -0.0035 9 0 0 0 5.13E+06 3.50E+05 - - - 1.2273 1 221125_WJC_METTL3_EV_vs_WT_F07.11913.11913.3 8.41E-07 Dec-44 K.K[136.11]DYNEAYNYYTK[136.11].A "sp|Q99615|DNJC7_HUMAN,tr|K7ESP1|K7ESP1_HUMAN,tr|A0A6I8PLE7|A0A6I8PLE7_HUMAN,tr|A0A6I8PR89|A0A6I8PR89_HUMAN,tr|A0A6I8PIK4|A0A6I8PIK4_HUMAN,tr|K7ELJ8|K7ELJ8_HUMAN,tr|A0A6I8PS32|A0A6I8PS32_HUMAN,tr|A0A6I8PUD4|A0A6I8PUD4_HUMAN,tr|K7EIH8|K7EIH8_HUMAN,tr|A0A6I8PU73|A0A6I8PU73_HUMAN,tr|K7EK03|K7EK03_HUMAN,tr|A0A6I8PU89|A0A6I8PU89_HUMAN" 12 1586.7224 1.08 99513 11913 3 1586.721983 529.9147 DnaJ homolog subfamily C member 7 OS=Homo sapiens OX=9606 GN=DNAJC7 PE=1 SV=2 6.07 2253.9 - 1.68E+06 - - - -0.2559 - 2.448 0.572 - 176.6 1 2 0 -0.0004 12 0 0 0 4.37E+07 4.06E+07 - - - 7.3987 0.9937 221125_WJC_METTL3_EV_vs_WT_F07.11918.11918.3 0.0816 Sep-40 R.HGESAWNLENR.F sp|P18669|PGAM1_HUMAN 1 1311.5956 1.27 99518 11918 3 1311.596462 438.2058 Phosphoglycerate mutase 1 OS=Homo sapiens OX=9606 GN=PGAM1 PE=1 SV=2 5.4 2254.3 - 385691 - - - 0.6481 - 1.636 0.193 - 95.9 1 2 0 0.0008 11 0 0 0 2.20E+07 1.73E+07 - - - 2.0899 1 221125_WJC_METTL3_EV_vs_WT_F07.11921.11921.2 4.89E-10 14/22 P.YGGGGQYFAKPR.N "sp|P09651|ROA1_HUMAN,tr|A0A7I2YQX9|A0A7I2YQX9_HUMAN,tr|A0A7I2V5N7|A0A7I2V5N7_HUMAN,tr|A0A7I2V661|A0A7I2V661_HUMAN,tr|A0A7I2V520|A0A7I2V520_HUMAN,tr|A0A7I2V2F1|A0A7I2V2F1_HUMAN,tr|A0A7I2V497|A0A7I2V497_HUMAN,tr|A0A7I2V3K5|A0A7I2V3K5_HUMAN,tr|A0A7I2V2M7|A0A7I2V2M7_HUMAN,tr|A0A7I2V4P7|A0A7I2V4P7_HUMAN,tr|A0A7I2V5P1|A0A7I2V5P1_HUMAN,tr|A0A7I2V334|A0A7I2V334_HUMAN,tr|A0A7I2V4E2|A0A7I2V4E2_HUMAN,tr|A0A7I2V4F8|A0A7I2V4F8_HUMAN,tr|A0A7I2V3R8|A0A7I2V3R8_HUMAN,tr|F8W6I7|F8W6I7_HUMAN,tr|A0A7I2V666|A0A7I2V666_HUMAN,tr|A0A7I2V2Q7|A0A7I2V2Q7_HUMAN,tr|A0A7I2V459|A0A7I2V459_HUMAN,tr|A0A7I2YQY2|A0A7I2YQY2_HUMAN,tr|H0YH80|H0YH80_HUMAN,tr|A0A7I2V3W0|A0A7I2V3W0_HUMAN,tr|A0A7I2V3U8|A0A7I2V3U8_HUMAN,tr|A0A7I2V2R4|A0A7I2V2R4_HUMAN,tr|A0A7I2V2X1|A0A7I2V2X1_HUMAN,tr|A0A7I2V453|A0A7I2V453_HUMAN,tr|A0A7I2V360|A0A7I2V360_HUMAN" 27 1299.636 1.68 99521 11921 2 1299.63677 650.8253 Heterogeneous nuclear ribonucleoprotein A1 OS=Homo sapiens OX=9606 GN=HNRNPA1 PE=1 SV=5 9.7 2254.7 - 169937 - - - 0.5771 - 2.68 0.67 - 642.4 1 1 0 0.0008 12 0 0 0 5.95E+06 3.54E+06 - - - 6.5832 1 221125_WJC_METTL3_EV_vs_WT_F07.11922.11922.2 1.44E-08 14/26 S.GPYGGGGQYFAKPR.N "sp|P09651|ROA1_HUMAN,tr|A0A7I2YQX9|A0A7I2YQX9_HUMAN,tr|A0A7I2V5N7|A0A7I2V5N7_HUMAN,tr|A0A7I2V661|A0A7I2V661_HUMAN,tr|A0A7I2V520|A0A7I2V520_HUMAN,tr|A0A7I2V2F1|A0A7I2V2F1_HUMAN,tr|A0A7I2V497|A0A7I2V497_HUMAN,tr|A0A7I2V3K5|A0A7I2V3K5_HUMAN,tr|A0A7I2V2M7|A0A7I2V2M7_HUMAN,tr|A0A7I2V4P7|A0A7I2V4P7_HUMAN,tr|A0A7I2V5P1|A0A7I2V5P1_HUMAN,tr|A0A7I2V334|A0A7I2V334_HUMAN,tr|A0A7I2V4E2|A0A7I2V4E2_HUMAN,tr|A0A7I2V4F8|A0A7I2V4F8_HUMAN,tr|A0A7I2V3R8|A0A7I2V3R8_HUMAN,tr|F8W6I7|F8W6I7_HUMAN,tr|A0A7I2V666|A0A7I2V666_HUMAN,tr|A0A7I2V2Q7|A0A7I2V2Q7_HUMAN,tr|A0A7I2V459|A0A7I2V459_HUMAN,tr|A0A7I2YQY2|A0A7I2YQY2_HUMAN,tr|H0YH80|H0YH80_HUMAN,tr|A0A7I2V3W0|A0A7I2V3W0_HUMAN,tr|A0A7I2V3U8|A0A7I2V3U8_HUMAN,tr|A0A7I2V2R4|A0A7I2V2R4_HUMAN,tr|A0A7I2V2X1|A0A7I2V2X1_HUMAN,tr|A0A7I2V453|A0A7I2V453_HUMAN,tr|A0A7I2V360|A0A7I2V360_HUMAN" 27 1453.7102 1.49 99522 11922 2 1453.709377 727.8624 Heterogeneous nuclear ribonucleoprotein A1 OS=Homo sapiens OX=9606 GN=HNRNPA1 PE=1 SV=5 9.7 2254.9 - 132557 - - - -0.5992 - 2.831 0.666 - 610.9 1 1 0 -0.0009 14 0 0 0 9.72E+06 6.53E+06 - - - 6.5712 0.9999 221125_WJC_METTL3_EV_vs_WT_F07.11926.11926.3 0.000757 Dec-56 R.NGLTHQLGGLSQGSR[166.11].N "sp|Q8N5F7|NKAP_HUMAN,tr|A0A494C050|A0A494C050_HUMAN" 2 1533.7887 0.57 99525 11926 3 1533.787782 512.2702 NF-kappa-B-activating protein OS=Homo sapiens OX=9606 GN=NKAP PE=1 SV=1 9.76 2255.3 - 2.72E+06 - - - -0.6135 - 2.643 0.39 - 157.7 1 2 0 -0.0009 15 0 0 0 1.94E+07 3.42E+07 - - - 5.4239 0.9866 221125_WJC_METTL3_EV_vs_WT_F07.11929.11929.3 0.152 Sep-56 K.AIR[166.11]DGVIEASINHEK[136.11].G sp|O43242|PSMD3_HUMAN 1 1668.8914 0.53 99528 11929 3 1668.888695 557.3044 26S proteasome non-ATPase regulatory subunit 3 OS=Homo sapiens OX=9606 GN=PSMD3 PE=1 SV=2 5.45 2255.6 - 420421 - - - -1.6226 - 1.826 0.241 - 71 1 2 1 -0.0027 15 0 0 0 1.36E+06 2.55E+06 - - - 2.7973 0.9983 221125_WJC_METTL3_EV_vs_WT_F07.11930.11930.2 0.125 24-Aug K.K[136.11]PLPDHVSIVEPK[136.11].D "sp|P23396|RS3_HUMAN,tr|H0YEU2|H0YEU2_HUMAN,tr|E9PSF4|E9PSF4_HUMAN,tr|E9PL09|E9PL09_HUMAN,tr|E9PPU1|E9PPU1_HUMAN" 5 1473.8526 0.6 99529 11930 2 1473.854488 737.9336 40S ribosomal protein S3 OS=Homo sapiens OX=9606 GN=RPS3 PE=1 SV=2 6.75 2255.7 - 416562 - - - 1.2708 - 1.332 0.336 - 155.7 1 2 0 0.0019 13 0 0 0 1.99E+06 3.34E+06 - - - 2.2579 0.9999 221125_WJC_METTL3_EV_vs_WT_F07.11936.11936.3 5.53E-07 21/56 K.EAALVQQEEEKAEQR.K "sp|Q15020|SART3_HUMAN,tr|A0A499FI31|A0A499FI31_HUMAN" 2 1756.8592 4.28 99533 11936 3 1756.861495 586.627 Squamous cell carcinoma antigen recognized by T-cells 3 OS=Homo sapiens OX=9606 GN=SART3 PE=1 SV=1 4.33 2256.4 - 1.24E+06 - - - 1.3314 - 3.5 0.577 - 720.4 1 2 1 0.0023 15 0 0 0 1.44E+08 3.36E+07 - - - 8.2413 0.9999 221125_WJC_METTL3_EV_vs_WT_F07.11937.11937.4 4.13E-06 17/84 R.SLDPADER[166.11]DDVLAK[136.11]R[166.11].L "sp|Q8WXI9|P66B_HUMAN,tr|A0A0U1RR34|A0A0U1RR34_HUMAN,tr|A0A0U1RRM1|A0A0U1RRM1_HUMAN,tr|A0A0U1RRK3|A0A0U1RRK3_HUMAN" 4 1726.8844 1.78 99534 11937 4 1726.884882 432.7284 Transcriptional repressor p66-beta OS=Homo sapiens OX=9606 GN=GATAD2B PE=1 SV=1 4.36 2256.5 - 940917 - - - 0.2693 - 2.931 0.491 - 199.2 1 2 1 0.0005 15 0 0 0 6.80E+07 3.81E+07 - - - 3.8843 0.999 221125_WJC_METTL3_EV_vs_WT_F07.11940.11940.3 0.0106 Oct-48 K.K[136.11]SGGATIEELTEK[136.11].C "sp|P18583|SON_HUMAN,tr|H7C1M2|H7C1M2_HUMAN,tr|H7C2G8|H7C2G8_HUMAN,tr|J3QSZ5|J3QSZ5_HUMAN" 4 1377.7322 0.13 99537 11940 3 1377.735384 460.2514 Protein SON OS=Homo sapiens OX=9606 GN=SON PE=1 SV=4 4.79 2256.8 - 573285 - - - 2.2929 - 2.157 0.301 - 127.2 1 2 0 0.0032 13 0 0 0 8.69E+06 6.49E+07 - - - 3.9792 1 221125_WJC_METTL3_EV_vs_WT_F07.11941.11941.2 9.56E-11 14/26 S.GPYGGGGQYFAK[136.11]PR[166.11].N "sp|P09651|ROA1_HUMAN,tr|A0A7I2YQX9|A0A7I2YQX9_HUMAN,tr|A0A7I2V5N7|A0A7I2V5N7_HUMAN,tr|A0A7I2V661|A0A7I2V661_HUMAN,tr|A0A7I2V520|A0A7I2V520_HUMAN,tr|A0A7I2V2F1|A0A7I2V2F1_HUMAN,tr|A0A7I2V497|A0A7I2V497_HUMAN,tr|A0A7I2V3K5|A0A7I2V3K5_HUMAN,tr|A0A7I2V2M7|A0A7I2V2M7_HUMAN,tr|A0A7I2V4P7|A0A7I2V4P7_HUMAN,tr|A0A7I2V5P1|A0A7I2V5P1_HUMAN,tr|A0A7I2V334|A0A7I2V334_HUMAN,tr|A0A7I2V4E2|A0A7I2V4E2_HUMAN,tr|A0A7I2V4F8|A0A7I2V4F8_HUMAN,tr|A0A7I2V3R8|A0A7I2V3R8_HUMAN,tr|F8W6I7|F8W6I7_HUMAN,tr|A0A7I2V666|A0A7I2V666_HUMAN,tr|A0A7I2V2Q7|A0A7I2V2Q7_HUMAN,tr|A0A7I2V459|A0A7I2V459_HUMAN,tr|A0A7I2YQY2|A0A7I2YQY2_HUMAN,tr|H0YH80|H0YH80_HUMAN,tr|A0A7I2V3W0|A0A7I2V3W0_HUMAN,tr|A0A7I2V3U8|A0A7I2V3U8_HUMAN,tr|A0A7I2V2R4|A0A7I2V2R4_HUMAN,tr|A0A7I2V2X1|A0A7I2V2X1_HUMAN,tr|A0A7I2V453|A0A7I2V453_HUMAN,tr|A0A7I2V360|A0A7I2V360_HUMAN" 27 1471.7327 1.51 99538 11941 2 1471.73006 736.8736 Heterogeneous nuclear ribonucleoprotein A1 OS=Homo sapiens OX=9606 GN=HNRNPA1 PE=1 SV=5 9.7 2257 - 478636 - - - -1.806 - 2.88 0.622 - 531.8 1 1 0 -0.0027 14 0 0 0 9.85E+06 6.53E+06 - - - 6.2887 1 221125_WJC_METTL3_EV_vs_WT_F07.11948.11948.3 0.0224 14/44 R.DQGPTFDYSHPR.D sp|O60512|B4GT3_HUMAN 1 1418.6215 1.24 99543 11948 3 1418.621178 473.8811 "Beta-1,4-galactosyltransferase 3 OS=Homo sapiens OX=9606 GN=B4GALT3 PE=1 SV=2" 5.21 2257.8 - 949118 - - - -0.2213 - 2.566 0.53 - 320 1 2 0 -0.0003 12 0 0 0 1.40E+07 1.13E+07 - - - 7.0609 1 221125_WJC_METTL3_EV_vs_WT_F07.11950.11950.2 1.80E-09 16/26 S.GPYGGGGQYFAKPR.N "sp|P09651|ROA1_HUMAN,tr|A0A7I2YQX9|A0A7I2YQX9_HUMAN,tr|A0A7I2V5N7|A0A7I2V5N7_HUMAN,tr|A0A7I2V661|A0A7I2V661_HUMAN,tr|A0A7I2V520|A0A7I2V520_HUMAN,tr|A0A7I2V2F1|A0A7I2V2F1_HUMAN,tr|A0A7I2V497|A0A7I2V497_HUMAN,tr|A0A7I2V3K5|A0A7I2V3K5_HUMAN,tr|A0A7I2V2M7|A0A7I2V2M7_HUMAN,tr|A0A7I2V4P7|A0A7I2V4P7_HUMAN,tr|A0A7I2V5P1|A0A7I2V5P1_HUMAN,tr|A0A7I2V334|A0A7I2V334_HUMAN,tr|A0A7I2V4E2|A0A7I2V4E2_HUMAN,tr|A0A7I2V4F8|A0A7I2V4F8_HUMAN,tr|A0A7I2V3R8|A0A7I2V3R8_HUMAN,tr|F8W6I7|F8W6I7_HUMAN,tr|A0A7I2V666|A0A7I2V666_HUMAN,tr|A0A7I2V2Q7|A0A7I2V2Q7_HUMAN,tr|A0A7I2V459|A0A7I2V459_HUMAN,tr|A0A7I2YQY2|A0A7I2YQY2_HUMAN,tr|H0YH80|H0YH80_HUMAN,tr|A0A7I2V3W0|A0A7I2V3W0_HUMAN,tr|A0A7I2V3U8|A0A7I2V3U8_HUMAN,tr|A0A7I2V2R4|A0A7I2V2R4_HUMAN,tr|A0A7I2V2X1|A0A7I2V2X1_HUMAN,tr|A0A7I2V453|A0A7I2V453_HUMAN,tr|A0A7I2V360|A0A7I2V360_HUMAN" 27 1453.7102 1.49 99545 11950 2 1453.712153 727.8624 Heterogeneous nuclear ribonucleoprotein A1 OS=Homo sapiens OX=9606 GN=HNRNPA1 PE=1 SV=5 9.7 2258 - 469808 - - - 1.3104 - 3.02 0.648 - 836.4 1 1 0 0.0019 14 0 0 0 9.72E+06 6.53E+06 - - - 6.6001 0.9998 221125_WJC_METTL3_EV_vs_WT_F07.11952.11952.2 0.000109 26-Aug K.IQSSHNFQLESVNK[136.11].L "sp|Q8NBJ4|GOLM1_HUMAN,tr|F8WAT9|F8WAT9_HUMAN,tr|C9JYM4|C9JYM4_HUMAN" 3 1637.8253 0.001 99547 11952 2 1637.824106 819.9199 Golgi membrane protein 1 OS=Homo sapiens OX=9606 GN=GOLM1 PE=1 SV=1 6.75 2258.3 - 239670 - - - -0.7192 - 1.917 0.472 - 189.9 1 2 0 -0.0012 14 0 0 0 0.00E+00 1.68E+06 - - - 4.1599 0.9995 221125_WJC_METTL3_EV_vs_WT_F07.11955.11955.3 0.0004 13/56 R.SLDPADER[166.11]DDVLAK[136.11]R[166.11].L "sp|Q8WXI9|P66B_HUMAN,tr|A0A0U1RR34|A0A0U1RR34_HUMAN,tr|A0A0U1RRM1|A0A0U1RRM1_HUMAN,tr|A0A0U1RRK3|A0A0U1RRK3_HUMAN" 4 1726.8844 2.88 99548 11955 3 1726.886682 576.6354 Transcriptional repressor p66-beta OS=Homo sapiens OX=9606 GN=GATAD2B PE=1 SV=1 4.36 2258.7 - 1.58E+06 - - - 1.3116 - 1.904 0.456 - 180.1 1 2 1 0.0023 15 0 0 0 6.87E+07 2.39E+07 - - - 5.3036 1 221125_WJC_METTL3_EV_vs_WT_F07.11956.11956.3 2.16E-08 17/48 K.GSGNLEAIHIIKK.L "sp|P78371|TCPB_HUMAN,tr|F8VQ14|F8VQ14_HUMAN,tr|F5GWF6|F5GWF6_HUMAN" 3 1378.7932 0.46 99549 11956 3 1378.791739 460.605 T-complex protein 1 subunit beta OS=Homo sapiens OX=9606 GN=CCT2 PE=1 SV=4 8.6 2258.8 - 1.23E+06 - - - -1.0952 - 3.07 0.508 - 405.5 1 2 0 -0.0015 13 0 0 0 1.78E+07 3.83E+07 - - - 7.2445 0.9995 221125_WJC_METTL3_EV_vs_WT_F07.11957.11957.3 2.93E-05 Nov-44 K.DR[166.11]EDYVPYTGEK[136.11].K sp|Q9NYL9|TMOD3_HUMAN 1 1488.6852 1.21 99550 11957 3 1488.680949 497.2357 Tropomodulin-3 OS=Homo sapiens OX=9606 GN=TMOD3 PE=1 SV=1 4.32 2258.9 - 842666 - - - -2.8273 - 2.115 0.508 - 207.4 1 2 1 -0.0042 12 0 0 0 1.94E+07 1.61E+07 - - - 6.2788 1 221125_WJC_METTL3_EV_vs_WT_F07.11965.11965.3 1.19E-07 13/48 K.GSGNLEAIHIIK[136.11]K[136.11].L "sp|P78371|TCPB_HUMAN,tr|F8VQ14|F8VQ14_HUMAN,tr|F5GWF6|F5GWF6_HUMAN" 3 1394.8216 0.47 99556 11965 3 1394.820396 465.9478 T-complex protein 1 subunit beta OS=Homo sapiens OX=9606 GN=CCT2 PE=1 SV=4 8.6 2259.9 - 4.56E+06 - - - -0.8983 - 2.938 0.58 - 207.4 1 2 0 -0.0013 13 0 0 0 1.79E+07 3.83E+07 - - - 7.9281 0.9992 221125_WJC_METTL3_EV_vs_WT_F07.11971.11971.3 0.0981 Dec-56 R.IFHTVTTTDDPVIRK.L "sp|O15371|EIF3D_HUMAN,tr|B0QYA5|B0QYA5_HUMAN,tr|B0QYA4|B0QYA4_HUMAN" 3 1741.9363 0.96 99562 11971 3 1741.934182 581.6527 Eukaryotic translation initiation factor 3 subunit D OS=Homo sapiens OX=9606 GN=EIF3D PE=1 SV=1 6.75 2260.4 - 795002 - - - -1.2073 - 2.436 0.238 - 195.4 1 2 0 -0.0021 15 0 0 0 5.96E+06 6.23E+06 - - - 3.5162 1 221125_WJC_METTL3_EV_vs_WT_F07.11974.11974.2 9.88E-09 28-Dec K.EAALVQQEEEKAEQR.K "sp|Q15020|SART3_HUMAN,tr|A0A499FI31|A0A499FI31_HUMAN" 2 1756.8592 9.95 99565 11974 2 1756.861205 879.4369 Squamous cell carcinoma antigen recognized by T-cells 3 OS=Homo sapiens OX=9606 GN=SART3 PE=1 SV=1 4.33 2260.8 - 230971 - - - 1.1663 - 2.795 0.579 - 489.3 1 2 1 0.002 15 0 0 0 4.68E+06 4.70E+05 - - - 5.8438 1 221125_WJC_METTL3_EV_vs_WT_F07.11978.11978.3 6.46E-10 18/48 K.KPLPDHVSIVEPK.D "sp|P23396|RS3_HUMAN,tr|H0YEU2|H0YEU2_HUMAN,tr|E9PSF4|E9PSF4_HUMAN,tr|E9PL09|E9PL09_HUMAN,tr|E9PPU1|E9PPU1_HUMAN" 5 1457.8242 0.76 99568 11978 3 1457.82316 486.9487 40S ribosomal protein S3 OS=Homo sapiens OX=9606 GN=RPS3 PE=1 SV=2 6.75 2261.2 - 4.64E+06 - - - -0.7237 - 3.608 0.585 - 432.7 1 2 0 -0.0011 13 0 0 0 1.28E+08 1.67E+08 - - - 8.5409 1 221125_WJC_METTL3_EV_vs_WT_F07.11979.11979.3 5.59E-05 13/44 R.TNAENEFVTIKK.D sp|P04264|K2C1_HUMAN 1 1392.7249 999 99569 11979 3 1392.723817 465.2489 "Keratin, type II cytoskeletal 1 OS=Homo sapiens OX=9606 GN=KRT1 PE=1 SV=6" 5.81 2261.2 - 6.22E+06 - - - -0.774 - 2.431 0.534 - 246.6 1 2 0 -0.0011 12 0 0 0 4.28E+09 0.00E+00 - - - 6.9555 0.9998 221125_WJC_METTL3_EV_vs_WT_F07.11980.11980.4 6.69E-07 17/84 R.SLDPADERDDVLAKR.L "sp|Q8WXI9|P66B_HUMAN,tr|A0A0U1RR34|A0A0U1RR34_HUMAN,tr|A0A0U1RRM1|A0A0U1RRM1_HUMAN,tr|A0A0U1RRK3|A0A0U1RRK3_HUMAN" 4 1698.8537 1.7 99570 11980 4 1698.851763 425.7207 Transcriptional repressor p66-beta OS=Homo sapiens OX=9606 GN=GATAD2B PE=1 SV=1 4.36 2261.3 - 6.03E+06 - - - -1.1266 - 2.373 0.473 - 202.9 1 2 1 -0.0019 15 0 0 0 6.83E+07 4.03E+07 - - - 3.6517 0.994 221125_WJC_METTL3_EV_vs_WT_F07.11981.11981.3 0.115 Sep-36 R.K[136.11]MVDQLFC[160.03]K[136.11]K[136.11].F "sp|P78347|GTF2I_HUMAN,tr|A0A494C0Q7|A0A494C0Q7_HUMAN,tr|A0A494C1K3|A0A494C1K3_HUMAN" 3 1319.7156 1.3 99571 11981 3 1319.716723 440.9125 General transcription factor II-I OS=Homo sapiens OX=9606 GN=GTF2I PE=1 SV=2 9.2 2261.4 - 1.35E+06 - - - 0.8509 - 1.59 0.202 - 127.2 1 2 0 0.0011 10 0 0 0 3.50E+07 2.70E+07 - - - 2.1461 0.9994 221125_WJC_METTL3_EV_vs_WT_F07.11982.11982.2 0.000367 26-Aug R.SSFYPDGGDQETAK[136.11].T "sp|Q9NYF8|BCLF1_HUMAN,tr|H0YF00|H0YF00_HUMAN,tr|E9PKI6|E9PKI6_HUMAN,tr|A0A1W2PQ43|A0A1W2PQ43_HUMAN,tr|E9PK91|E9PK91_HUMAN,tr|E9PJA7|E9PJA7_HUMAN,tr|E9PK09|E9PK09_HUMAN,tr|E9PQN2|E9PQN2_HUMAN" 8 1508.6511 2.22 99572 11982 2 1508.654398 755.3328 Bcl-2-associated transcription factor 1 OS=Homo sapiens OX=9606 GN=BCLAF1 PE=1 SV=2 4.03 2261.5 - 636091 - - - 2.2073 - 1.407 0.556 - 82.3 1 2 0 0.0033 14 0 0 0 2.06E+08 9.25E+07 - - - 4.0034 0.9999 221125_WJC_METTL3_EV_vs_WT_F07.11984.11984.2 4.03E-07 26-Dec R.SSFYPDGGDQETAK.T "sp|Q9NYF8|BCLF1_HUMAN,tr|H0YF00|H0YF00_HUMAN,tr|E9PKI6|E9PKI6_HUMAN,tr|A0A1W2PQ43|A0A1W2PQ43_HUMAN,tr|E9PK91|E9PK91_HUMAN,tr|E9PJA7|E9PJA7_HUMAN,tr|E9PK09|E9PK09_HUMAN,tr|E9PQN2|E9PQN2_HUMAN" 8 1500.6369 2.22 99574 11984 2 1500.635295 751.3257 Bcl-2-associated transcription factor 1 OS=Homo sapiens OX=9606 GN=BCLAF1 PE=1 SV=2 4.03 2261.7 - 578507 - - - -1.0482 - 1.919 0.619 - 274.5 1 2 0 -0.0016 14 0 0 0 2.06E+08 9.25E+07 - - - 5.2481 1 221125_WJC_METTL3_EV_vs_WT_F07.11985.11985.2 0.00964 14/22 R.TNAENEFVTIKK.D sp|P04264|K2C1_HUMAN 1 1392.7249 999 99575 11985 2 1392.726436 697.3697 "Keratin, type II cytoskeletal 1 OS=Homo sapiens OX=9606 GN=KRT1 PE=1 SV=6" 5.81 2261.9 - 483093 - - - 1.1065 - 2.855 0.591 - 671.1 1 2 0 0.0015 12 0 0 0 4.64E+08 0.00E+00 - - - 6.1659 0.9998 221125_WJC_METTL3_EV_vs_WT_F07.11986.11986.4 5.46E-05 13/90 R.SSGPYGGGGQYFAKPR.N "sp|P09651|ROA1_HUMAN,tr|A0A7I2YQX9|A0A7I2YQX9_HUMAN,tr|A0A7I2V5N7|A0A7I2V5N7_HUMAN,tr|A0A7I2V661|A0A7I2V661_HUMAN,tr|A0A7I2V520|A0A7I2V520_HUMAN,tr|A0A7I2V2F1|A0A7I2V2F1_HUMAN,tr|A0A7I2V497|A0A7I2V497_HUMAN,tr|A0A7I2V3K5|A0A7I2V3K5_HUMAN,tr|A0A7I2V2M7|A0A7I2V2M7_HUMAN,tr|A0A7I2V4P7|A0A7I2V4P7_HUMAN,tr|A0A7I2V5P1|A0A7I2V5P1_HUMAN,tr|A0A7I2V334|A0A7I2V334_HUMAN,tr|A0A7I2V4E2|A0A7I2V4E2_HUMAN,tr|A0A7I2V4F8|A0A7I2V4F8_HUMAN,tr|A0A7I2V3R8|A0A7I2V3R8_HUMAN,tr|F8W6I7|F8W6I7_HUMAN,tr|A0A7I2V666|A0A7I2V666_HUMAN,tr|A0A7I2V2Q7|A0A7I2V2Q7_HUMAN,tr|A0A7I2V459|A0A7I2V459_HUMAN,tr|A0A7I2YQY2|A0A7I2YQY2_HUMAN,tr|H0YH80|H0YH80_HUMAN,tr|A0A7I2V3W0|A0A7I2V3W0_HUMAN,tr|A0A7I2V3U8|A0A7I2V3U8_HUMAN,tr|A0A7I2V2R4|A0A7I2V2R4_HUMAN,tr|A0A7I2V2X1|A0A7I2V2X1_HUMAN,tr|A0A7I2V453|A0A7I2V453_HUMAN,tr|A0A7I2V360|A0A7I2V360_HUMAN" 27 1627.7743 0.94 99576 11986 4 1627.769846 407.9509 Heterogeneous nuclear ribonucleoprotein A1 OS=Homo sapiens OX=9606 GN=HNRNPA1 PE=1 SV=5 9.7 2262 - 482941 - - - -2.7393 - 2.389 0.438 - 109.8 1 2 0 -0.0045 16 0 0 0 5.59E+06 5.92E+06 - - - 3.3439 1 221125_WJC_METTL3_EV_vs_WT_F07.11987.11987.2 5.52E-09 24-Nov R.NSQSSSVSYLESK[136.11].S "sp|Q92576|PHF3_HUMAN,tr|E9PE34|E9PE34_HUMAN,tr|E7EVH3|E7EVH3_HUMAN,tr|D6R9X2|D6R9X2_HUMAN,tr|A0A1B0GX99|A0A1B0GX99_HUMAN" 5 1422.6718 0.53 99577 11987 2 1422.67025 712.3432 PHD finger protein 3 OS=Homo sapiens OX=9606 GN=PHF3 PE=1 SV=3 6 2262.1 - 445186 - - - -1.0916 - 2.541 0.614 - 478.3 1 2 0 -0.0016 13 0 0 0 3.26E+06 6.13E+06 - - - 5.969 1 221125_WJC_METTL3_EV_vs_WT_F07.11991.11991.3 1.40E-09 20/48 K.K[136.11]PLPDHVSIVEPK[136.11].D "sp|P23396|RS3_HUMAN,tr|H0YEU2|H0YEU2_HUMAN,tr|E9PSF4|E9PSF4_HUMAN,tr|E9PL09|E9PL09_HUMAN,tr|E9PPU1|E9PPU1_HUMAN" 5 1473.8526 0.79 99580 11991 3 1473.851808 492.2915 40S ribosomal protein S3 OS=Homo sapiens OX=9606 GN=RPS3 PE=1 SV=2 6.75 2262.5 - 6.63E+06 - - - -0.5475 - 3.651 0.59 - 574.5 1 2 0 -0.0008 13 0 0 0 8.78E+07 1.11E+08 - - - 8.6288 0.9999 221125_WJC_METTL3_EV_vs_WT_F07.11995.11995.3 9.06E-07 Dec-52 K.DAHSQGEVVSC[160.03]LEK[136.11].G "sp|Q92896|GSLG1_HUMAN,tr|H3BQT1|H3BQT1_HUMAN,tr|H3BM42|H3BM42_HUMAN" 3 1565.7235 1.63 99584 11995 3 1565.718622 522.9151 Golgi apparatus protein 1 OS=Homo sapiens OX=9606 GN=GLG1 PE=1 SV=2 4.65 2262.9 - 938119 - - - -3.1289 - 2.559 0.5 - 218.3 1 2 0 -0.0049 14 0 0 0 2.13E+07 1.31E+07 - - - 6.6102 0.9998 221125_WJC_METTL3_EV_vs_WT_F07.11996.11996.3 1.74E-05 Dec-48 R.SLENYHFVDEHGK.D sp|Q14677|EPN4_HUMAN 1 1573.7161 1.78 99585 11996 3 1573.71094 525.5793 Clathrin interactor 1 OS=Homo sapiens OX=9606 GN=CLINT1 PE=1 SV=1 5.26 2263 - 886787 - - - -3.2922 - 2.297 0.496 - 138.5 1 2 0 -0.0052 13 0 0 0 8.64E+07 4.85E+07 - - - 6.3232 0.9999 221125_WJC_METTL3_EV_vs_WT_F07.11997.11997.4 2.83E-05 13/72 R.SLENYHFVDEHGK.D sp|Q14677|EPN4_HUMAN 1 1573.7161 1.75 99586 11997 4 1573.714954 394.4363 Clathrin interactor 1 OS=Homo sapiens OX=9606 GN=CLINT1 PE=1 SV=1 5.26 2263.1 - 673642 - - - -0.7416 - 2.332 0.399 - 89.3 1 2 0 -0.0012 13 0 0 0 9.72E+07 5.55E+07 - - - 3.0125 0.9996 221125_WJC_METTL3_EV_vs_WT_F07.12002.12002.3 0.000868 Dec-56 R.SLDPADERDDVLAKR.L "sp|Q8WXI9|P66B_HUMAN,tr|A0A0U1RR34|A0A0U1RR34_HUMAN,tr|A0A0U1RRM1|A0A0U1RRM1_HUMAN,tr|A0A0U1RRK3|A0A0U1RRK3_HUMAN" 4 1698.8537 2.8 99589 12002 3 1698.851195 567.2918 Transcriptional repressor p66-beta OS=Homo sapiens OX=9606 GN=GATAD2B PE=1 SV=1 4.36 2263.7 - 3.97E+06 - - - -1.461 - 1.806 0.49 - 149.7 1 2 1 -0.0025 15 0 0 0 6.90E+07 2.46E+07 - - - 5.5448 0.9999 221125_WJC_METTL3_EV_vs_WT_F07.12009.12009.3 1.89E-06 13/40 K.KLLELDPEHQR.A sp|P13674|P4HA1_HUMAN 1 1376.7412 21.57 99594 12009 3 1376.742968 459.921 Prolyl 4-hydroxylase subunit alpha-1 OS=Homo sapiens OX=9606 GN=P4HA1 PE=1 SV=2 5.45 2264.5 - 1.69E+06 - - - 1.2747 - 2.664 0.42 - 314.8 1 2 0 0.0018 11 0 0 0 7.90E+07 3.66E+06 - - - 6.0056 1 221125_WJC_METTL3_EV_vs_WT_F07.12010.12010.4 8.11E-07 17/72 R.SLENYHFVDEHGK[136.11].D sp|Q14677|EPN4_HUMAN 1 1581.7303 1.75 99595 12010 4 1581.729064 396.4399 Clathrin interactor 1 OS=Homo sapiens OX=9606 GN=CLINT1 PE=1 SV=1 5.26 2264.6 - 2.22E+06 - - - -0.7947 - 2.71 0.509 - 173.1 1 2 0 -0.0013 13 0 0 0 9.69E+07 5.55E+07 - - - 4.0256 0.9884 221125_WJC_METTL3_EV_vs_WT_F07.12013.12013.2 8.64E-06 18-Nov A.AENEFVTLKK.D "sp|P48668|K2C6C_HUMAN,sp|P12035|K2C3_HUMAN,sp|P04264|K2C1_HUMAN,sp|P04259|K2C6B_HUMAN,sp|P02538|K2C6A_HUMAN" 5 1177.6343 999 99598 12013 2 1177.635495 589.8244 "Keratin, type II cytoskeletal 6C OS=Homo sapiens OX=9606 GN=KRT6C PE=1 SV=3" 6.19 2264.9 - 770796 - - - 1.0241 - 2.299 0.43 - 546.4 1 1 0 0.0012 10 0 0 0 4.67E+07 0.00E+00 - - - 4.5403 1 221125_WJC_METTL3_EV_vs_WT_F07.12019.12019.3 0.000504 17/56 R.LQQSHPLSATQIQVK.R "sp|Q13813|SPTN1_HUMAN,tr|A0A0D9SF54|A0A0D9SF54_HUMAN,tr|A0A0D9SGF6|A0A0D9SGF6_HUMAN" 3 1676.921 1.36 99602 12019 3 1676.919927 559.9809 "Spectrin alpha chain, non-erythrocytic 1 OS=Homo sapiens OX=9606 GN=SPTAN1 PE=1 SV=3" 8.76 2265.8 - 3.31E+06 - - - -0.6214 - 3.218 0.509 - 367 1 2 0 -0.001 15 0 0 0 4.96E+07 3.64E+07 - - - 7.2643 1 221125_WJC_METTL3_EV_vs_WT_F07.12020.12020.3 5.51E-05 Dec-56 R.LQQSHPLSATQIQVK[136.11].R "sp|Q13813|SPTN1_HUMAN,tr|A0A0D9SF54|A0A0D9SF54_HUMAN,tr|A0A0D9SGF6|A0A0D9SGF6_HUMAN" 3 1684.9352 1.35 99603 12020 3 1684.9347 562.6523 "Spectrin alpha chain, non-erythrocytic 1 OS=Homo sapiens OX=9606 GN=SPTAN1 PE=1 SV=3" 8.76 2265.8 - 2.67E+06 - - - -0.2783 - 2.48 0.475 - 208.8 1 2 0 -0.0005 15 0 0 0 4.93E+07 3.64E+07 - - - 6.2056 0.9992 221125_WJC_METTL3_EV_vs_WT_F07.12021.12021.3 0.000194 Sep-60 K.VGEEFEEQTVDGRPC[160.03]K.S sp|P29373|RABP2_HUMAN 1 1878.8418 11.07 99604 12021 3 1878.838862 627.2879 Cellular retinoic acid-binding protein 2 OS=Homo sapiens OX=9606 GN=CRABP2 PE=1 SV=2 4.25 2265.9 - 1.31E+06 - - - -1.5595 - 2.124 0.287 - 105.8 1 2 0 -0.0029 16 0 0 0 2.54E+07 2.30E+06 - - - 3.6718 1 221125_WJC_METTL3_EV_vs_WT_F07.12022.12022.2 1.46E-07 16/20 T.NAENEFVTIKK.D sp|P04264|K2C1_HUMAN 1 1291.6772 999 99605 12022 2 1291.682542 646.8459 "Keratin, type II cytoskeletal 1 OS=Homo sapiens OX=9606 GN=KRT1 PE=1 SV=6" 6.14 2266 - 1.08E+06 - - - 4.1233 - 2.944 0.591 - 1070 1 1 0 0.0053 11 0 0 0 2.81E+07 0.00E+00 - - - 6.3255 0.9999 221125_WJC_METTL3_EV_vs_WT_F07.12028.12028.3 0.00594 14/64 R.EIVHLQAGQC[160.03]GNQIGAK.F "sp|P04350|TBB4A_HUMAN,sp|Q9BVA1|TBB2B_HUMAN,sp|P07437|TBB5_HUMAN,sp|Q13509|TBB3_HUMAN,sp|Q13885|TBB2A_HUMAN,sp|P68371|TBB4B_HUMAN,tr|M0R2D3|M0R2D3_HUMAN,tr|G3V3W7|G3V3W7_HUMAN,tr|M0R2T4|M0R2T4_HUMAN,tr|G3V3R4|G3V3R4_HUMAN,tr|M0R042|M0R042_HUMAN,tr|M0QY85|M0QY85_HUMAN,tr|M0QZL7|M0QZL7_HUMAN,tr|G3V5W4|G3V5W4_HUMAN,tr|M0R0X0|M0R0X0_HUMAN,tr|M0QYM7|M0QYM7_HUMAN,tr|G3V4U2|G3V4U2_HUMAN,tr|M0R278|M0R278_HUMAN,tr|M0QY37|M0QY37_HUMAN,tr|G3V2R8|G3V2R8_HUMAN,tr|G3V3J6|G3V3J6_HUMAN,tr|M0QX14|M0QX14_HUMAN,tr|G3V2N6|G3V2N6_HUMAN" 23 1821.9156 0.61 99609 12028 3 1821.913734 608.3125 Tubulin beta-4A chain OS=Homo sapiens OX=9606 GN=TUBB4A PE=1 SV=2 6.83 2266.8 - 2.55E+06 - - - -1.0055 - 2.824 0.391 - 319.3 1 2 0 -0.0018 17 0 0 0 3.74E+08 6.15E+08 - - - 5.5214 0.9999 221125_WJC_METTL3_EV_vs_WT_F07.12029.12029.3 0.0002 Nov-36 R.KMVDQLFC[160.03]KK.F "sp|P78347|GTF2I_HUMAN,tr|A0A494C0Q7|A0A494C0Q7_HUMAN,tr|A0A494C1K3|A0A494C1K3_HUMAN" 3 1295.673 1.09 99610 12029 3 1295.671846 432.8983 General transcription factor II-I OS=Homo sapiens OX=9606 GN=GTF2I PE=1 SV=2 9.2 2266.8 - 1.23E+06 - - - -0.8907 - 2.034 0.424 - 194.5 1 2 0 -0.0012 10 0 0 0 2.87E+07 2.62E+07 - - - 5.3404 0.9998 221125_WJC_METTL3_EV_vs_WT_F07.12030.12030.2 1.86E-05 13/22 R.EDITQSAQHALR[166.11].L sp|Q12906|ILF3_HUMAN 1 1377.6876 1.16 99611 12030 2 1377.685405 689.8511 Interleukin enhancer-binding factor 3 OS=Homo sapiens OX=9606 GN=ILF3 PE=1 SV=3 5.32 2267 - 970841 - - - -1.6012 - 2.667 0.433 - 849.6 1 2 0 -0.0022 12 0 0 0 6.51E+07 5.60E+07 - - - 4.8195 1 221125_WJC_METTL3_EV_vs_WT_F07.12037.12037.3 2.25E-06 15/64 R.LVK[136.11]PGNQNTQVTEAWNK[136.11].V "sp|Q9UQ80|PA2G4_HUMAN,tr|F8W0A3|F8W0A3_HUMAN,tr|F8VR77|F8VR77_HUMAN,tr|H0YIN7|H0YIN7_HUMAN" 4 1942.0243 0.14 99616 12037 3 1942.022485 648.3487 Proliferation-associated protein 2G4 OS=Homo sapiens OX=9606 GN=PA2G4 PE=1 SV=3 8.59 2267.9 - 1.70E+06 - - - -0.9475 - 2.52 0.466 - 169.2 1 2 0 -0.0018 17 0 0 0 2.97E+07 2.11E+08 - - - 6.0699 1 221125_WJC_METTL3_EV_vs_WT_F07.12038.12038.3 1.41E-05 16/72 R.MESQLSASKPTGGLPETAR.E "sp|Q9UPN3|MACF1_HUMAN,tr|A0A804HL78|A0A804HL78_HUMAN,tr|H3BQK9|H3BQK9_HUMAN,tr|A0A7P0MQR8|A0A7P0MQR8_HUMAN,tr|H0Y390|H0Y390_HUMAN,tr|H3BPE1|H3BPE1_HUMAN,tr|A0A590UJG2|A0A590UJG2_HUMAN" 7 1958.9731 1.9 99617 12038 3 1958.973223 653.9983 "Microtubule-actin cross-linking factor 1, isoforms 1\2\3\5 OS=Homo sapiens OX=9606 GN=MACF1 PE=1 SV=4" 5.9 2268 - 462278 - - - 0.0424 - 2.368 0.49 - 141.5 1 2 0 0.0001 19 0 0 0 4.72E+06 2.49E+06 - - - 6.1209 1 221125_WJC_METTL3_EV_vs_WT_F07.12045.12045.2 1.33E-08 15/32 R.EIVHLQAGQC[160.03]GNQIGAK[136.11].F "sp|P04350|TBB4A_HUMAN,sp|Q9BVA1|TBB2B_HUMAN,sp|P07437|TBB5_HUMAN,sp|Q13509|TBB3_HUMAN,sp|Q13885|TBB2A_HUMAN,sp|P68371|TBB4B_HUMAN,tr|M0R2D3|M0R2D3_HUMAN,tr|G3V3W7|G3V3W7_HUMAN,tr|M0R2T4|M0R2T4_HUMAN,tr|G3V3R4|G3V3R4_HUMAN,tr|M0R042|M0R042_HUMAN,tr|M0QY85|M0QY85_HUMAN,tr|M0QZL7|M0QZL7_HUMAN,tr|G3V5W4|G3V5W4_HUMAN,tr|M0R0X0|M0R0X0_HUMAN,tr|M0QYM7|M0QYM7_HUMAN,tr|G3V4U2|G3V4U2_HUMAN,tr|M0R278|M0R278_HUMAN,tr|M0QY37|M0QY37_HUMAN,tr|G3V2R8|G3V2R8_HUMAN,tr|G3V3J6|G3V3J6_HUMAN,tr|M0QX14|M0QX14_HUMAN,tr|G3V2N6|G3V2N6_HUMAN" 23 1829.9298 0.53 99622 12045 2 1829.92943 915.9722 Tubulin beta-4A chain OS=Homo sapiens OX=9606 GN=TUBB4A PE=1 SV=2 6.83 2268.9 - 647713 - - - -0.1836 - 3.113 0.584 - 569.7 1 2 0 -0.0003 17 0 0 0 1.21E+07 2.27E+07 - - - 6.1462 1 221125_WJC_METTL3_EV_vs_WT_F07.12047.12047.2 6.47E-06 13/26 K.K[136.11]ITESVAETAQTIK[136.11].K sp|Q96A49|SYAP1_HUMAN 1 1533.8585 1.48 99624 12047 2 1533.855694 767.9365 Synapse-associated protein 1 OS=Homo sapiens OX=9606 GN=SYAP1 PE=1 SV=1 6.14 2269.1 - 277626 - - - -1.8216 - 2.944 0.566 - 321.5 1 2 0 -0.0028 14 0 0 0 4.19E+08 2.83E+08 - - - 5.9302 0.9998 221125_WJC_METTL3_EV_vs_WT_F07.12052.12052.3 9.28E-05 14/56 K.MQEHSDQVPVGNIPR[166.11].S "sp|P33993|MCM7_HUMAN,tr|C9J8M6|C9J8M6_HUMAN" 2 1715.8289 6.07 99627 12052 3 1715.823825 572.9502 DNA replication licensing factor MCM7 OS=Homo sapiens OX=9606 GN=MCM7 PE=1 SV=4 5.3 2269.7 - 766996 - - - -2.942 - 2.201 0.484 - 205.2 1 2 0 -0.005 15 0 0 0 2.45E+08 4.04E+07 - - - 5.9933 0.9999 221125_WJC_METTL3_EV_vs_WT_F07.12053.12053.3 3.30E-05 Dec-52 K.K[136.11]ITESVAETAQTIK[136.11].K sp|Q96A49|SYAP1_HUMAN 1 1533.8585 1.34 99628 12053 3 1533.855585 512.2934 Synapse-associated protein 1 OS=Homo sapiens OX=9606 GN=SYAP1 PE=1 SV=1 6.14 2269.7 - 1.11E+06 - - - -1.8926 - 2.399 0.466 - 245.2 1 2 0 -0.0029 14 0 0 0 7.16E+08 5.33E+08 - - - 6.0601 0.9706 221125_WJC_METTL3_EV_vs_WT_F07.12056.12056.3 0.108 Nov-44 K.QQIESEVANLKK.T sp|Q9UBW8|CSN7A_HUMAN 1 1385.7514 0.68 99631 12056 3 1385.756362 462.9244 COP9 signalosome complex subunit 7a OS=Homo sapiens OX=9606 GN=COPS7A PE=1 SV=1 6.14 2270.1 - 606992 - - - 3.549 - 2.027 0.153 - 184.9 1 2 0 0.0049 12 0 0 0 1.54E+07 2.26E+07 - - - 2.2029 0.9999 221125_WJC_METTL3_EV_vs_WT_F07.12059.12059.3 5.14E-05 13/52 K.KITESVAETAQTIK.K sp|Q96A49|SYAP1_HUMAN 1 1517.8301 1.34 99632 12059 3 1517.831998 506.9506 Synapse-associated protein 1 OS=Homo sapiens OX=9606 GN=SYAP1 PE=1 SV=1 6.14 2270.5 - 1.92E+06 - - - 1.2584 - 2.616 0.353 - 292.9 1 2 0 0.0019 14 0 0 0 7.16E+08 5.33E+08 - - - 5.0307 1 221125_WJC_METTL3_EV_vs_WT_F07.12060.12060.2 3.43E-11 20/26 K.KITESVAETAQTIK.K sp|Q96A49|SYAP1_HUMAN 1 1517.8301 1.48 99633 12060 2 1517.82905 759.9223 Synapse-associated protein 1 OS=Homo sapiens OX=9606 GN=SYAP1 PE=1 SV=1 6.14 2270.7 - 992036 - - - -0.6839 - 4.227 0.6 - 1064.9 1 2 0 -0.001 14 0 0 0 4.19E+08 2.83E+08 - - - 7.0896 1 221125_WJC_METTL3_EV_vs_WT_F07.12065.12065.2 1.66E-07 16/32 R.EIVHLQAGQC[160.03]GNQIGAK.F "sp|P04350|TBB4A_HUMAN,sp|Q9BVA1|TBB2B_HUMAN,sp|P07437|TBB5_HUMAN,sp|Q13509|TBB3_HUMAN,sp|Q13885|TBB2A_HUMAN,sp|P68371|TBB4B_HUMAN,tr|M0R2D3|M0R2D3_HUMAN,tr|G3V3W7|G3V3W7_HUMAN,tr|M0R2T4|M0R2T4_HUMAN,tr|G3V3R4|G3V3R4_HUMAN,tr|M0R042|M0R042_HUMAN,tr|M0QY85|M0QY85_HUMAN,tr|M0QZL7|M0QZL7_HUMAN,tr|G3V5W4|G3V5W4_HUMAN,tr|M0R0X0|M0R0X0_HUMAN,tr|M0QYM7|M0QYM7_HUMAN,tr|G3V4U2|G3V4U2_HUMAN,tr|M0R278|M0R278_HUMAN,tr|M0QY37|M0QY37_HUMAN,tr|G3V2R8|G3V2R8_HUMAN,tr|G3V3J6|G3V3J6_HUMAN,tr|M0QX14|M0QX14_HUMAN,tr|G3V2N6|G3V2N6_HUMAN" 23 1821.9156 0.53 99638 12065 2 1821.912905 911.9651 Tubulin beta-4A chain OS=Homo sapiens OX=9606 GN=TUBB4A PE=1 SV=2 6.83 2271.2 - 645056 - - - -1.4606 - 3.52 0.589 - 686.6 1 2 0 -0.0027 17 0 0 0 1.21E+07 2.27E+07 - - - 6.4845 0.9929 221125_WJC_METTL3_EV_vs_WT_F07.12066.12066.4 1.05E-06 15/90 Y.ATVEEVDAAMNARPHK.V "sp|P09651|ROA1_HUMAN,tr|A0A7I2YQX9|A0A7I2YQX9_HUMAN,tr|A0A7I2V3W4|A0A7I2V3W4_HUMAN,tr|F8W646|F8W646_HUMAN,tr|F8VZ49|F8VZ49_HUMAN,tr|A0A7I2V3R8|A0A7I2V3R8_HUMAN,tr|F8W6I7|F8W6I7_HUMAN,tr|F8VYN5|F8VYN5_HUMAN,tr|A0A7I2V2L6|A0A7I2V2L6_HUMAN,tr|A0A7I2V3C7|A0A7I2V3C7_HUMAN,tr|A0A7I2V3W0|A0A7I2V3W0_HUMAN,tr|A0A7I2YQV3|A0A7I2YQV3_HUMAN,tr|A0A2R8Y4L2|A0A2R8Y4L2_HUMAN,tr|A0A7I2V2Z4|A0A7I2V2Z4_HUMAN,tr|A0A7I2V4M0|A0A7I2V4M0_HUMAN" 15 1737.8468 1.51 99639 12066 4 1737.844641 435.469 Heterogeneous nuclear ribonucleoprotein A1 OS=Homo sapiens OX=9606 GN=HNRNPA1 PE=1 SV=5 5.45 2271.4 - 636756 - - - -1.2527 - 3.066 0.448 - 267.4 1 1 0 -0.0022 16 0 0 0 1.79E+08 1.19E+08 - - - 3.5194 0.9999 221125_WJC_METTL3_EV_vs_WT_F07.12067.12067.3 2.01E-05 19/68 R.LRGPSGGGEEPALSQYQR.L "sp|Q99567|NUP88_HUMAN,tr|J3KMX1|J3KMX1_HUMAN" 2 1900.9391 1.89 99640 12067 3 1900.938766 634.6537 Nuclear pore complex protein Nup88 OS=Homo sapiens OX=9606 GN=NUP88 PE=1 SV=2 6.14 2271.5 - 612909 - - - -0.1957 - 3.313 0.516 - 517.9 1 2 1 -0.0004 18 0 0 0 8.34E+07 4.42E+07 - - - 7.2756 0.9999 221125_WJC_METTL3_EV_vs_WT_F07.12069.12069.3 1.10E-06 13/64 R.LVKPGNQNTQVTEAWNK.V "sp|Q9UQ80|PA2G4_HUMAN,tr|F8W0A3|F8W0A3_HUMAN,tr|F8VR77|F8VR77_HUMAN,tr|H0YIN7|H0YIN7_HUMAN" 4 1925.9959 0.14 99642 12069 3 1925.999935 643.0059 Proliferation-associated protein 2G4 OS=Homo sapiens OX=9606 GN=PA2G4 PE=1 SV=3 8.59 2271.7 - 554130 - - - 2.082 - 2.322 0.46 - 197.9 1 2 0 0.004 17 0 0 0 2.97E+07 2.11E+08 - - - 5.7957 0.9808 221125_WJC_METTL3_EV_vs_WT_F07.12073.12073.2 0.00489 16-Sep R.K[136.11]IELFGR[166.11]PH.N sp|Q86U44|MTA70_HUMAN 1 1113.6414 0 99644 12073 2 1113.640678 557.828 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 8.75 2272.3 - 3.26E+06 - - - -0.6331 - 2 0.338 - 258.5 1 1 0 -0.0007 9 0 0 0 1.26E+05 7.09E+08 - - - 3.5426 1 221125_WJC_METTL3_EV_vs_WT_F07.12074.12074.3 0.0148 15/56 K.DGVPEGAQLQGPVHR.N sp|P16989|YBOX3_HUMAN 1 1558.7852 1.14 99645 12074 3 1558.784911 520.6023 Y-box-binding protein 3 OS=Homo sapiens OX=9606 GN=YBX3 PE=1 SV=4 5.32 2272.3 - 1.91E+06 - - - -0.188 - 3.133 0.454 - 333 1 2 0 -0.0003 15 0 0 0 2.31E+08 2.02E+08 - - - 6.5814 0.9988 221125_WJC_METTL3_EV_vs_WT_F07.12076.12076.2 0.0749 12-Jun R.LAADDFR.T "sp|Q04695|K1C17_HUMAN,sp|P13645|K1C10_HUMAN,sp|O76015|KRT38_HUMAN,sp|Q2M2I5|K1C24_HUMAN,sp|Q15323|K1H1_HUMAN,sp|P02533|K1C14_HUMAN,sp|P05783|K1C18_HUMAN,sp|P08727|K1C19_HUMAN,sp|P08779|K1C16_HUMAN,sp|Q7Z3Y7|K1C28_HUMAN,sp|Q14532|K1H2_HUMAN,sp|P19012|K1C15_HUMAN,sp|O76013|KRT36_HUMAN,sp|Q14525|KT33B_HUMAN,sp|Q92764|KRT35_HUMAN,sp|O76014|KRT37_HUMAN,sp|P13646|K1C13_HUMAN,tr|F8VZY9|F8VZY9_HUMAN,tr|K7EPJ9|K7EPJ9_HUMAN,tr|C9JM50|C9JM50_HUMAN,tr|A0A1B0GVI3|A0A1B0GVI3_HUMAN,tr|K7EMD9|K7EMD9_HUMAN,tr|F5GWP8|F5GWP8_HUMAN,tr|K7ERE3|K7ERE3_HUMAN,tr|C4AM86|C4AM86_HUMAN" 25 806.3923 13.42 99647 12076 2 806.391855 404.2034 "Keratin, type I cytoskeletal 17 OS=Homo sapiens OX=9606 GN=KRT17 PE=1 SV=2" 4.21 2272.6 - 1.08E+06 - - - -0.5109 - 1.56 0.237 - 123.1 1 2 0 -0.0004 7 0 0 0 1.83E+07 1.36E+06 - - - 2.2004 1 221125_WJC_METTL3_EV_vs_WT_F07.12077.12077.3 0.00073 23/76 K.LPQQSHSAFGATSSSSGFGK.S "sp|Q86XP3|DDX42_HUMAN,tr|J3QRI2|J3QRI2_HUMAN,tr|J3KTK9|J3KTK9_HUMAN" 3 1979.9337 1.13 99648 12077 3 1979.931978 660.9852 ATP-dependent RNA helicase DDX42 OS=Homo sapiens OX=9606 GN=DDX42 PE=1 SV=1 8.76 2272.7 - 928681 - - - -0.8788 - 3.839 0.566 - 600.1 1 2 0 -0.0017 20 0 0 0 2.72E+07 2.41E+07 - - - 8.1134 0.9988 221125_WJC_METTL3_EV_vs_WT_F07.12078.12078.3 3.71E-05 24/76 K.LPQQSHSAFGATSSSSGFGK[136.11].S "sp|Q86XP3|DDX42_HUMAN,tr|J3QRI2|J3QRI2_HUMAN,tr|J3KTK9|J3KTK9_HUMAN" 3 1987.9479 1.03 99649 12078 3 1988.957115 663.6566 ATP-dependent RNA helicase DDX42 OS=Homo sapiens OX=9606 GN=DDX42 PE=1 SV=1 8.76 2272.9 - 789911 - - - 507.6577 - 4.347 0.559 - 906.6 1 2 0 1.0092 20 0 0 0 2.74E+07 2.66E+07 - - - 8.0578 0.9999 221125_WJC_METTL3_EV_vs_WT_F07.12079.12079.3 2.05E-05 Nov-48 K.GFSEEHNTWEPEK.N "sp|P45973|CBX5_HUMAN,tr|F8VNY3|F8VNY3_HUMAN" 2 1588.6794 0.63 99650 12079 3 1588.675799 530.5671 Chromobox protein homolog 5 OS=Homo sapiens OX=9606 GN=CBX5 PE=1 SV=1 4.48 2273 - 746297 - - - -2.2673 - 1.836 0.489 - 85.5 1 2 0 -0.0036 13 0 0 0 3.27E+07 5.19E+07 - - - 5.6382 0.9909 221125_WJC_METTL3_EV_vs_WT_F07.12080.12080.4 3.27E-05 18/90 Y.ATVEEVDAAMNAR[166.11]PHK[136.11].V "sp|P09651|ROA1_HUMAN,tr|A0A7I2YQX9|A0A7I2YQX9_HUMAN,tr|A0A7I2V3W4|A0A7I2V3W4_HUMAN,tr|F8W646|F8W646_HUMAN,tr|F8VZ49|F8VZ49_HUMAN,tr|A0A7I2V3R8|A0A7I2V3R8_HUMAN,tr|F8W6I7|F8W6I7_HUMAN,tr|F8VYN5|F8VYN5_HUMAN,tr|A0A7I2V2L6|A0A7I2V2L6_HUMAN,tr|A0A7I2V3C7|A0A7I2V3C7_HUMAN,tr|A0A7I2V3W0|A0A7I2V3W0_HUMAN,tr|A0A7I2YQV3|A0A7I2YQV3_HUMAN,tr|A0A2R8Y4L2|A0A2R8Y4L2_HUMAN,tr|A0A7I2V2Z4|A0A7I2V2Z4_HUMAN,tr|A0A7I2V4M0|A0A7I2V4M0_HUMAN" 15 1755.8693 1.51 99651 12080 4 1755.870126 439.9746 Heterogeneous nuclear ribonucleoprotein A1 OS=Homo sapiens OX=9606 GN=HNRNPA1 PE=1 SV=5 5.45 2273.1 - 745250 - - - 0.4773 - 3.363 0.426 - 393.6 1 1 0 0.0008 16 0 0 0 1.79E+08 1.19E+08 - - - 3.3609 1 221125_WJC_METTL3_EV_vs_WT_F07.12081.12081.2 2.17E-10 17/36 S.SLVSGLNSSASEPAK[136.11]EPAK[136.11].K "sp|Q86U44|MTA70_HUMAN,tr|F5H6D8|F5H6D8_HUMAN,tr|H0YFV6|H0YFV6_HUMAN,tr|B4DTN4|B4DTN4_HUMAN" 4 1886.992 0.001 99652 12081 2 1886.990419 944.5033 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 5.86 2273.3 - 702490 - - - -0.8495 - 3.537 0.542 - 710.4 1 1 1 -0.0016 19 0 0 0 0.00E+00 2.76E+07 - - - 6.1495 0.9989 221125_WJC_METTL3_EV_vs_WT_F07.12083.12083.3 1.29E-06 18/60 Y.ATVEEVDAAMNARPHK.V "sp|P09651|ROA1_HUMAN,tr|A0A7I2YQX9|A0A7I2YQX9_HUMAN,tr|A0A7I2V3W4|A0A7I2V3W4_HUMAN,tr|F8W646|F8W646_HUMAN,tr|F8VZ49|F8VZ49_HUMAN,tr|A0A7I2V3R8|A0A7I2V3R8_HUMAN,tr|F8W6I7|F8W6I7_HUMAN,tr|F8VYN5|F8VYN5_HUMAN,tr|A0A7I2V2L6|A0A7I2V2L6_HUMAN,tr|A0A7I2V3C7|A0A7I2V3C7_HUMAN,tr|A0A7I2V3W0|A0A7I2V3W0_HUMAN,tr|A0A7I2YQV3|A0A7I2YQV3_HUMAN,tr|A0A2R8Y4L2|A0A2R8Y4L2_HUMAN,tr|A0A7I2V2Z4|A0A7I2V2Z4_HUMAN,tr|A0A7I2V4M0|A0A7I2V4M0_HUMAN" 15 1737.8468 1.25 99654 12083 3 1737.847356 580.2895 Heterogeneous nuclear ribonucleoprotein A1 OS=Homo sapiens OX=9606 GN=HNRNPA1 PE=1 SV=5 5.45 2273.5 - 482173 - - - 0.3096 - 3.856 0.557 - 532.1 1 1 0 0.0005 16 0 0 0 1.06E+08 8.49E+07 - - - 8.2128 1 221125_WJC_METTL3_EV_vs_WT_F07.12088.12088.3 0.000329 13/60 R.SSGPYGGGGQYFAKPR.N "sp|P09651|ROA1_HUMAN,tr|A0A7I2YQX9|A0A7I2YQX9_HUMAN,tr|A0A7I2V5N7|A0A7I2V5N7_HUMAN,tr|A0A7I2V661|A0A7I2V661_HUMAN,tr|A0A7I2V520|A0A7I2V520_HUMAN,tr|A0A7I2V2F1|A0A7I2V2F1_HUMAN,tr|A0A7I2V497|A0A7I2V497_HUMAN,tr|A0A7I2V3K5|A0A7I2V3K5_HUMAN,tr|A0A7I2V2M7|A0A7I2V2M7_HUMAN,tr|A0A7I2V4P7|A0A7I2V4P7_HUMAN,tr|A0A7I2V5P1|A0A7I2V5P1_HUMAN,tr|A0A7I2V334|A0A7I2V334_HUMAN,tr|A0A7I2V4E2|A0A7I2V4E2_HUMAN,tr|A0A7I2V4F8|A0A7I2V4F8_HUMAN,tr|A0A7I2V3R8|A0A7I2V3R8_HUMAN,tr|F8W6I7|F8W6I7_HUMAN,tr|A0A7I2V666|A0A7I2V666_HUMAN,tr|A0A7I2V2Q7|A0A7I2V2Q7_HUMAN,tr|A0A7I2V459|A0A7I2V459_HUMAN,tr|A0A7I2YQY2|A0A7I2YQY2_HUMAN,tr|H0YH80|H0YH80_HUMAN,tr|A0A7I2V3W0|A0A7I2V3W0_HUMAN,tr|A0A7I2V3U8|A0A7I2V3U8_HUMAN,tr|A0A7I2V2R4|A0A7I2V2R4_HUMAN,tr|A0A7I2V2X1|A0A7I2V2X1_HUMAN,tr|A0A7I2V453|A0A7I2V453_HUMAN,tr|A0A7I2V360|A0A7I2V360_HUMAN" 27 1627.7743 1.26 99658 12088 3 1627.775673 543.5987 Heterogeneous nuclear ribonucleoprotein A1 OS=Homo sapiens OX=9606 GN=HNRNPA1 PE=1 SV=5 9.7 2274.1 - 1.58E+06 - - - 0.8404 - 2.672 0.56 - 282.9 1 2 0 0.0014 16 0 0 0 3.09E+09 2.46E+09 - - - 7.3049 1 221125_WJC_METTL3_EV_vs_WT_F07.12092.12092.3 3.92E-08 17/56 K.DGVPEGAQLQGPVHR[166.11].N sp|P16989|YBOX3_HUMAN 1 1568.7935 1.14 99661 12092 3 1568.79501 523.9384 Y-box-binding protein 3 OS=Homo sapiens OX=9606 GN=YBX3 PE=1 SV=4 5.32 2274.4 - 3.67E+06 - - - 0.9791 - 3.069 0.595 - 434.5 1 2 0 0.0015 15 0 0 0 2.30E+08 2.02E+08 - - - 8.0993 1 221125_WJC_METTL3_EV_vs_WT_F07.12093.12093.3 8.65E-05 15/52 R.IEDVTPIPSDSTR[166.11]R[166.11].K "sp|P62263|RS14_HUMAN,tr|A0A2R8Y811|A0A2R8Y811_HUMAN" 2 1604.8273 1.37 99662 12093 3 1604.830302 535.9497 40S ribosomal protein S14 OS=Homo sapiens OX=9606 GN=RPS14 PE=1 SV=3 4.56 2274.5 - 2.96E+06 - - - 1.8768 - 3.046 0.469 - 371.6 1 2 0 0.003 14 0 0 0 2.94E+09 2.14E+09 - - - 6.7281 1 221125_WJC_METTL3_EV_vs_WT_F07.12094.12094.2 5.46E-10 19/32 R.GSGGLGGAC[160.03]GGAGFGSR.S "sp|P48668|K2C6C_HUMAN,sp|P04259|K2C6B_HUMAN,sp|P02538|K2C6A_HUMAN" 3 1423.6263 999 99663 12094 2 1423.626091 712.8204 "Keratin, type II cytoskeletal 6C OS=Homo sapiens OX=9606 GN=KRT6C PE=1 SV=3" 8.25 2274.5 - 2.95E+06 - - - -0.1187 - 3.592 0.611 - 923.7 1 2 0 -0.0002 17 0 0 0 9.36E+07 0.00E+00 - - - 6.6976 1 221125_WJC_METTL3_EV_vs_WT_F07.12095.12095.3 3.13E-11 20/68 R.LR[166.11]GPSGGGEEPALSQYQR[166.11].L "sp|Q99567|NUP88_HUMAN,tr|J3KMX1|J3KMX1_HUMAN" 2 1920.9557 1.89 99664 12095 3 1920.953835 641.3258 Nuclear pore complex protein Nup88 OS=Homo sapiens OX=9606 GN=NUP88 PE=1 SV=2 6.14 2274.7 - 1.89E+06 - - - -0.9594 - 4.166 0.622 - 471.1 1 2 1 -0.0018 18 0 0 0 8.34E+07 4.42E+07 - - - 9.0274 0.9316 221125_WJC_METTL3_EV_vs_WT_F07.12102.12102.2 0.0839 14-Sep K.IELFGR[166.11]PH.N sp|Q86U44|MTA70_HUMAN 1 977.5322 0.01 99669 12102 2 977.532117 489.7734 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 6.75 2275.6 - 1.69E+06 - - - -0.1054 - 1.678 0.215 - 263.5 1 1 0 -0.0001 8 0 0 0 7.39E+05 7.67E+07 - - - 2.19 0.9999 221125_WJC_METTL3_EV_vs_WT_F07.12103.12103.3 0.000162 15/52 R.IEDVTPIPSDSTRR.K "sp|P62263|RS14_HUMAN,tr|A0A2R8Y811|A0A2R8Y811_HUMAN" 2 1584.8108 1.37 99670 12103 3 1584.811711 529.2775 40S ribosomal protein S14 OS=Homo sapiens OX=9606 GN=RPS14 PE=1 SV=3 4.56 2275.6 - 6.71E+06 - - - 0.6064 - 2.883 0.346 - 363.3 1 2 0 0.001 14 0 0 0 2.94E+09 2.14E+09 - - - 5.2112 1 221125_WJC_METTL3_EV_vs_WT_F07.12104.12104.3 1.42E-05 Dec-48 K.RVC[160.03]EEIAIIPSKK.L "sp|P08708|RS17_HUMAN,tr|H0YN73|H0YN73_HUMAN,tr|H3BNC9|H3BNC9_HUMAN,tr|H0YN88|H0YN88_HUMAN,tr|A0A075B716|A0A075B716_HUMAN" 5 1541.8599 1.5 99671 12104 3 1541.859151 514.9606 40S ribosomal protein S17 OS=Homo sapiens OX=9606 GN=RPS17 PE=1 SV=2 8.2 2275.7 - 860697 - - - -0.5176 - 2.412 0.559 - 207.9 1 2 0 -0.0008 13 0 0 0 4.04E+07 2.70E+07 - - - 7.1592 0.9999 221125_WJC_METTL3_EV_vs_WT_F07.12107.12107.3 2.04E-09 18/56 R.GKETEYQALQETNMK.F "sp|Q15643|TRIPB_HUMAN,tr|H0YJ97|H0YJ97_HUMAN" 2 1768.8302 1.34 99674 12107 3 1768.828162 590.6173 Thyroid receptor-interacting protein 11 OS=Homo sapiens OX=9606 GN=TRIP11 PE=1 SV=3 4.79 2276 - 614757 - - - -1.1324 - 3.287 0.554 - 487.6 1 2 1 -0.002 15 0 0 0 6.88E+07 5.14E+07 - - - 7.8211 0.9998 221125_WJC_METTL3_EV_vs_WT_F07.12111.12111.3 1.23E-05 13/56 R.GK[136.11]ETEYQALQETNMK[136.11].F "sp|Q15643|TRIPB_HUMAN,tr|H0YJ97|H0YJ97_HUMAN" 2 1784.8586 1.34 99676 12111 3 1784.860062 595.9601 Thyroid receptor-interacting protein 11 OS=Homo sapiens OX=9606 GN=TRIP11 PE=1 SV=3 4.79 2276.5 - 1.33E+06 - - - 0.8387 - 2.897 0.427 - 244.2 1 2 1 0.0015 15 0 0 0 6.88E+07 5.14E+07 - - - 6.0757 1 221125_WJC_METTL3_EV_vs_WT_F07.12112.12112.3 5.71E-07 21/60 Y.ATVEEVDAAMNAR[166.11]PHK[136.11].V "sp|P09651|ROA1_HUMAN,tr|A0A7I2YQX9|A0A7I2YQX9_HUMAN,tr|A0A7I2V3W4|A0A7I2V3W4_HUMAN,tr|F8W646|F8W646_HUMAN,tr|F8VZ49|F8VZ49_HUMAN,tr|A0A7I2V3R8|A0A7I2V3R8_HUMAN,tr|F8W6I7|F8W6I7_HUMAN,tr|F8VYN5|F8VYN5_HUMAN,tr|A0A7I2V2L6|A0A7I2V2L6_HUMAN,tr|A0A7I2V3C7|A0A7I2V3C7_HUMAN,tr|A0A7I2V3W0|A0A7I2V3W0_HUMAN,tr|A0A7I2YQV3|A0A7I2YQV3_HUMAN,tr|A0A2R8Y4L2|A0A2R8Y4L2_HUMAN,tr|A0A7I2V2Z4|A0A7I2V2Z4_HUMAN,tr|A0A7I2V4M0|A0A7I2V4M0_HUMAN" 15 1755.8693 1.48 99677 12112 3 1755.872163 586.297 Heterogeneous nuclear ribonucleoprotein A1 OS=Homo sapiens OX=9606 GN=HNRNPA1 PE=1 SV=5 5.45 2276.6 - 1.18E+06 - - - 1.6374 - 4.296 0.569 - 927.9 1 1 0 0.0029 16 0 0 0 1.03E+08 6.94E+07 - - - 8.6232 0.9999 221125_WJC_METTL3_EV_vs_WT_F07.12115.12115.3 1.52E-05 Dec-52 K.K[136.11]ITESVAETAQTIK.K sp|Q96A49|SYAP1_HUMAN 1 1525.8443 - 99680 12115 3 1525.844689 509.622 Synapse-associated protein 1 OS=Homo sapiens OX=9606 GN=SYAP1 PE=1 SV=1 6.14 2276.9 - 643022 - - - 0.2628 - 2.39 0.435 - 201.9 1 2 0 0.0004 14 0 0 0 - - - - - 5.7052 0.9995 221125_WJC_METTL3_EV_vs_WT_F07.12116.12116.2 0.106 13/26 R.IEDVTPIPSDSTRR.K "sp|P62263|RS14_HUMAN,tr|A0A2R8Y811|A0A2R8Y811_HUMAN" 2 1584.8108 1.44 99681 12116 2 1584.812604 793.4127 40S ribosomal protein S14 OS=Homo sapiens OX=9606 GN=RPS14 PE=1 SV=3 4.56 2277 - 602946 - - - 1.1699 - 2.173 0.342 - 261.7 1 2 0 0.0019 14 0 0 0 2.37E+08 1.64E+08 - - - 3.514 0.9997 221125_WJC_METTL3_EV_vs_WT_F07.12117.12117.2 0.00116 Sep-32 R.LVK[136.11]PGNQNTQVTEAWNK[136.11].V "sp|Q9UQ80|PA2G4_HUMAN,tr|F8W0A3|F8W0A3_HUMAN,tr|F8VR77|F8VR77_HUMAN,tr|H0YIN7|H0YIN7_HUMAN" 4 1942.0243 0.001 99682 12117 2 1942.02564 972.0194 Proliferation-associated protein 2G4 OS=Homo sapiens OX=9606 GN=PA2G4 PE=1 SV=3 8.59 2277.1 - 310072 - - - 0.6771 - 1.591 0.497 - 107.3 1 2 0 0.0013 17 0 0 0 0.00E+00 2.89E+06 - - - 3.8531 1 221125_WJC_METTL3_EV_vs_WT_F07.12119.12119.3 1.35E-07 16/44 R.EDITQSAQHALR[166.11].L sp|Q12906|ILF3_HUMAN 1 1377.6876 1.12 99683 12119 3 1377.689229 460.2365 Interleukin enhancer-binding factor 3 OS=Homo sapiens OX=9606 GN=ILF3 PE=1 SV=3 5.32 2277.4 - 2.71E+06 - - - 1.1744 - 2.952 0.522 - 680.8 1 2 0 0.0016 12 0 0 0 4.52E+08 4.01E+08 - - - 7.3598 0.9996 221125_WJC_METTL3_EV_vs_WT_F07.12121.12121.2 0.000402 26-Oct R.IEDVTPIPSDSTR[166.11]R[166.11].K "sp|P62263|RS14_HUMAN,tr|A0A2R8Y811|A0A2R8Y811_HUMAN" 2 1604.8273 1.45 99684 12121 2 1604.82674 803.4209 40S ribosomal protein S14 OS=Homo sapiens OX=9606 GN=RPS14 PE=1 SV=3 4.56 2277.6 - 934110 - - - -0.3427 - 1.774 0.391 - 168.7 1 2 0 -0.0006 14 0 0 0 2.39E+08 1.64E+08 - - - 3.3673 0.9998 221125_WJC_METTL3_EV_vs_WT_F07.12122.12122.2 4.94E-06 28-Oct K.DGVPEGAQLQGPVHR[166.11].N sp|P16989|YBOX3_HUMAN 1 1568.7935 0.98 99685 12122 2 1568.793385 785.404 Y-box-binding protein 3 OS=Homo sapiens OX=9606 GN=YBX3 PE=1 SV=4 5.32 2277.7 - 422155 - - - -0.0567 - 2.176 0.477 - 236.1 1 2 0 -0.0001 15 0 0 0 1.11E+07 1.13E+07 - - - 4.4756 0.9976 221125_WJC_METTL3_EV_vs_WT_F07.12125.12125.2 0.165 26-Jul K.KITESVAETAQTIK[136.11].K sp|Q96A49|SYAP1_HUMAN 1 1525.8443 - 99688 12125 2 1525.843468 763.9294 Synapse-associated protein 1 OS=Homo sapiens OX=9606 GN=SYAP1 PE=1 SV=1 6.14 2278.1 - 322935 - - - -0.5374 - 1.673 0.182 - 104.7 1 2 0 -0.0008 14 0 0 0 - - - - - 1.6764 0.9997 221125_WJC_METTL3_EV_vs_WT_F07.12130.12130.3 0.0015 Dec-36 R.LKYENEVALR.Q "sp|P13645|K1C10_HUMAN,tr|A0A1B0GVI3|A0A1B0GVI3_HUMAN" 2 1233.6717 8.62 99691 12130 3 1233.671095 412.2312 "Keratin, type I cytoskeletal 10 OS=Homo sapiens OX=9606 GN=KRT10 PE=1 SV=6" 6.14 2278.6 - 2.54E+06 - - - -0.5204 - 2.477 0.414 - 167.8 1 2 1 -0.0006 10 0 0 0 1.20E+08 1.39E+07 - - - 5.8045 0.9999 221125_WJC_METTL3_EV_vs_WT_F07.12141.12141.4 0.00087 14/72 R.VSHYIINSLPNR[166.11]R[166.11].F sp|P46109|CRKL_HUMAN 1 1587.8748 0.38 99700 12141 4 1587.874074 397.976 Crk-like protein OS=Homo sapiens OX=9606 GN=CRKL PE=1 SV=1 10.83 2279.9 - 644937 - - - -0.4881 - 2.298 0.427 - 252.5 1 2 0 -0.0008 13 0 0 0 5.74E+06 1.51E+07 - - - 3.2509 0.9999 221125_WJC_METTL3_EV_vs_WT_F07.12146.12146.3 0.000285 16/48 K.VIQYLAHVASSHK[136.11].G sp|P35580|MYH10_HUMAN 1 1459.8027 0.89 99703 12146 3 1459.800508 487.6082 Myosin-10 OS=Homo sapiens OX=9606 GN=MYH10 PE=1 SV=3 8.58 2280.5 - 4.23E+06 - - - -1.5002 - 2.936 0.342 - 344.7 1 2 0 -0.0022 13 0 0 0 1.71E+08 1.92E+08 - - - 5.2725 0.9974 221125_WJC_METTL3_EV_vs_WT_F07.12150.12150.2 0.000335 18-Nov R.LKYENEVALR.Q "sp|P13645|K1C10_HUMAN,tr|A0A1B0GVI3|A0A1B0GVI3_HUMAN" 2 1233.6717 999 99707 12150 2 1233.669878 617.8431 "Keratin, type I cytoskeletal 10 OS=Homo sapiens OX=9606 GN=KRT10 PE=1 SV=6" 6.14 2280.9 - 1.03E+06 - - - -1.5069 - 2.037 0.469 - 292.4 1 2 1 -0.0019 10 0 0 0 1.99E+07 0.00E+00 - - - 4.4904 1 221125_WJC_METTL3_EV_vs_WT_F07.12151.12151.2 3.63E-09 28-Dec K.DGVPEGAQLQGPVHR.N sp|P16989|YBOX3_HUMAN 1 1558.7852 0.98 99708 12151 2 1558.787284 780.3999 Y-box-binding protein 3 OS=Homo sapiens OX=9606 GN=YBX3 PE=1 SV=4 5.32 2281.1 - 422811 - - - 1.3344 - 2.548 0.625 - 386.1 1 2 0 0.0021 15 0 0 0 1.11E+07 1.13E+07 - - - 5.9561 0.9917 221125_WJC_METTL3_EV_vs_WT_F07.12154.12154.3 0.251 17/64 R.EIVHLQAGQC[160.03]GNQIGAK[136.11].F "sp|P04350|TBB4A_HUMAN,sp|Q9BVA1|TBB2B_HUMAN,sp|P07437|TBB5_HUMAN,sp|Q13509|TBB3_HUMAN,sp|Q13885|TBB2A_HUMAN,sp|P68371|TBB4B_HUMAN,tr|M0R2D3|M0R2D3_HUMAN,tr|G3V3W7|G3V3W7_HUMAN,tr|M0R2T4|M0R2T4_HUMAN,tr|G3V3R4|G3V3R4_HUMAN,tr|M0R042|M0R042_HUMAN,tr|M0QY85|M0QY85_HUMAN,tr|M0QZL7|M0QZL7_HUMAN,tr|G3V5W4|G3V5W4_HUMAN,tr|M0R0X0|M0R0X0_HUMAN,tr|M0QYM7|M0QYM7_HUMAN,tr|G3V4U2|G3V4U2_HUMAN,tr|M0R278|M0R278_HUMAN,tr|M0QY37|M0QY37_HUMAN,tr|G3V2R8|G3V2R8_HUMAN,tr|G3V3J6|G3V3J6_HUMAN,tr|M0QX14|M0QX14_HUMAN,tr|G3V2N6|G3V2N6_HUMAN" 23 1829.9298 0.84 99710 12154 3 1829.936172 610.9839 Tubulin beta-4A chain OS=Homo sapiens OX=9606 GN=TUBB4A PE=1 SV=2 6.83 2281.4 - 841342 - - - 3.5007 - 2.537 0.191 - 292.3 1 2 0 0.0064 17 0 0 0 4.42E+08 5.23E+08 - - - 3.0196 0.9999 221125_WJC_METTL3_EV_vs_WT_F07.12156.12156.3 0.00215 14/60 K.EAIESAIGGNAYQHSK[136.11].V sp|P63172|DYLT1_HUMAN 1 1681.8151 0.94 99711 12156 3 1681.812089 561.6123 Dynein light chain Tctex-type 1 OS=Homo sapiens OX=9606 GN=DYNLT1 PE=1 SV=1 5.4 2281.6 - 1.77E+06 - - - -1.7981 - 2.732 0.466 - 244.3 1 2 0 -0.003 16 0 0 0 9.04E+07 9.59E+07 - - - 6.3134 1 221125_WJC_METTL3_EV_vs_WT_F07.12158.12158.3 7.58E-07 19/44 R.HNAEVAAFHLDR[166.11].L sp|O75063|XYLK_HUMAN 1 1388.6825 1.14 99712 12158 3 1388.68067 463.9014 Glycosaminoglycan xylosylkinase OS=Homo sapiens OX=9606 GN=FAM20B PE=1 SV=1 5.99 2281.8 - 883596 - - - -1.2933 - 3.489 0.588 - 514.9 1 2 0 -0.0018 12 0 0 0 6.57E+07 5.76E+07 - - - 8.5589 1 221125_WJC_METTL3_EV_vs_WT_F07.12160.12160.3 1.25E-05 16/48 K.VIQYLAHVASSHK.G sp|P35580|MYH10_HUMAN 1 1451.7885 0.89 99714 12160 3 1451.7872 484.9368 Myosin-10 OS=Homo sapiens OX=9606 GN=MYH10 PE=1 SV=3 8.58 2282 - 4.46E+06 - - - -0.8941 - 2.863 0.491 - 364.9 1 2 0 -0.0013 13 0 0 0 1.71E+08 1.92E+08 - - - 6.8657 1 221125_WJC_METTL3_EV_vs_WT_F07.12165.12165.3 0.0131 17/52 R.IEDVTPIPSDSTRR[166.11].K "sp|P62263|RS14_HUMAN,tr|A0A2R8Y811|A0A2R8Y811_HUMAN" 2 1594.819 - 99717 12165 3 1594.817298 532.6136 40S ribosomal protein S14 OS=Homo sapiens OX=9606 GN=RPS14 PE=1 SV=3 4.56 2282.6 - 1.61E+06 - - - -1.0797 - 2.971 0.44 - 367.5 1 2 0 -0.0017 14 0 0 0 - - - - - 6.3389 0.9157 221125_WJC_METTL3_EV_vs_WT_F07.12168.12168.3 0.0708 Dec-44 R.STSHK[136.11]PDEIYGM.L sp|Q86U44|MTA70_HUMAN 1 1371.622 0.01 99718 12168 3 1371.619095 458.2146 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 5.3 2283 - 2.07E+06 - - - -2.1296 - 1.753 0.343 - 126.6 1 1 0 -0.0029 12 0 0 0 7.22E+06 5.53E+08 - - - 3.9192 0.9961 221125_WJC_METTL3_EV_vs_WT_F07.12169.12169.3 4.20E-09 17/60 T.TVTSHLNSTSVDPYDR.H sp|Q9BQ04|RBM4B_HUMAN 1 1790.8435 0.28 99719 12169 3 1790.838554 597.9551 RNA-binding protein 4B OS=Homo sapiens OX=9606 GN=RBM4B PE=1 SV=1 5.18 2283.1 - 865890 - - - -2.7652 - 2.763 0.611 - 250 1 1 0 -0.005 16 0 0 0 5.13E+07 1.80E+08 - - - 7.9584 0.9753 221125_WJC_METTL3_EV_vs_WT_F07.12175.12175.2 5.02E-06 22-Sep R.STSHK[136.11]PDEIYGM.L sp|Q86U44|MTA70_HUMAN 1 1371.622 0 99722 12175 2 1371.618262 686.8183 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 5.3 2283.8 - 1.14E+06 - - - -2.7369 - 1.925 0.568 - 204.1 1 1 0 -0.0038 12 0 0 0 4.43E+05 2.03E+08 - - - 4.9583 1 221125_WJC_METTL3_EV_vs_WT_F07.12177.12177.3 1.71E-08 14/52 R.K[136.11]SGYAIQADEEQLR[166.11].V sp|Q7Z3B4|NUP54_HUMAN 1 1624.8176 0.001 99723 12177 3 1624.818254 542.6131 Nucleoporin p54 OS=Homo sapiens OX=9606 GN=NUP54 PE=1 SV=2 4.68 2284 - 2.03E+06 - - - 0.421 - 2.778 0.515 - 376.6 1 2 0 0.0007 14 0 0 0 0.00E+00 4.60E+07 - - - 6.9968 1 221125_WJC_METTL3_EV_vs_WT_F07.12184.12184.3 9.82E-10 19/60 T.TVTSHLNSTSVDPYDR[166.11].H sp|Q9BQ04|RBM4B_HUMAN 1 1800.8518 0.25 99727 12184 3 1800.84446 601.2912 RNA-binding protein 4B OS=Homo sapiens OX=9606 GN=RBM4B PE=1 SV=1 5.18 2284.9 - 1.17E+06 - - - -4.0625 - 3.362 0.631 - 337.5 1 1 0 -0.0073 16 0 0 0 5.13E+07 2.04E+08 - - - 8.6842 1 221125_WJC_METTL3_EV_vs_WT_F07.12191.12191.3 8.32E-11 18/68 K.QGVTSVTC[160.03]HGGYVYTTGR[166.11].D "sp|Q9NNW5|WDR6_HUMAN,tr|E9PDU5|E9PDU5_HUMAN,tr|A0A087X295|A0A087X295_HUMAN" 3 1951.9086 2.66 99731 12191 3 1951.900962 651.6435 WD repeat-containing protein 6 OS=Homo sapiens OX=9606 GN=WDR6 PE=1 SV=1 8.21 2285.7 - 691138 - - - -3.9028 - 4.17 0.647 - 418 1 2 0 -0.0076 18 0 0 0 3.77E+07 1.42E+07 - - - 9.307 0.9956 221125_WJC_METTL3_EV_vs_WT_F07.12192.12192.3 0.0205 13/44 R.EQVEVVEFHSNK.K "sp|Q8NDD1|CA131_HUMAN,tr|Q5TBI2|Q5TBI2_HUMAN,tr|Q5TBH9|Q5TBH9_HUMAN" 3 1443.6994 12.34 99732 12192 3 1443.700092 482.2404 Uncharacterized protein C1orf131 OS=Homo sapiens OX=9606 GN=C1orf131 PE=1 SV=4 4.75 2285.8 - 805942 - - - 0.4738 - 1.842 0.187 - 203.7 1 2 0 0.0007 12 0 0 0 1.58E+07 1.28E+06 - - - 2.3179 1 221125_WJC_METTL3_EV_vs_WT_F07.12196.12196.3 2.97E-07 18/68 K.QGVTSVTC[160.03]HGGYVYTTGR.D "sp|Q9NNW5|WDR6_HUMAN,tr|E9PDU5|E9PDU5_HUMAN,tr|A0A087X295|A0A087X295_HUMAN" 3 1941.9003 3.67 99734 12196 3 1941.895181 648.3074 WD repeat-containing protein 6 OS=Homo sapiens OX=9606 GN=WDR6 PE=1 SV=1 8.21 2286.3 - 1.42E+06 - - - -2.6412 - 3.423 0.55 - 361.5 1 2 0 -0.0051 18 0 0 0 5.87E+07 1.60E+07 - - - 7.7347 1 221125_WJC_METTL3_EV_vs_WT_F07.12197.12197.3 1.08E-05 17/44 R.DNIQGITK[136.11]PAIR[166.11].R sp|P62805|H4_HUMAN 1 1342.7688 1.11 99735 12197 3 1342.767472 448.5969 Histone H4 OS=Homo sapiens OX=9606 GN=H4C1 PE=1 SV=2 8.75 2286.4 - 1.17E+06 - - - -0.9659 - 2.845 0.509 - 513.3 1 2 0 -0.0013 12 0 0 0 2.12E+08 1.92E+08 - - - 7.1126 0.9998 221125_WJC_METTL3_EV_vs_WT_F07.12198.12198.3 0.000177 14/68 K.LSPPVASGGIPHQSPPTK.V sp|Q96T58|MINT_HUMAN 1 1768.9472 1.63 99736 12198 3 1768.946233 590.6563 Msx2-interacting protein OS=Homo sapiens OX=9606 GN=SPEN PE=1 SV=1 8.76 2286.6 - 1.02E+06 - - - -0.5376 - 2.254 0.358 - 122.7 1 2 0 -0.0009 18 0 0 0 2.88E+07 1.77E+07 - - - 4.5548 0.9999 221125_WJC_METTL3_EV_vs_WT_F07.12199.12199.3 1.98E-05 15/44 R.R[166.11]HEQFIPIAADK[136.11].R "sp|Q9Y520|PRC2C_HUMAN,tr|E7EPN9|E7EPN9_HUMAN" 2 1441.7797 0.99 99737 12199 3 1441.775676 481.6005 Protein PRRC2C OS=Homo sapiens OX=9606 GN=PRRC2C PE=1 SV=4 6.75 2286.7 - 872329 - - - -2.7688 - 2.688 0.441 - 410.6 1 2 0 -0.004 12 0 0 0 2.83E+07 2.85E+07 - - - 6.1964 0.999 221125_WJC_METTL3_EV_vs_WT_F07.12202.12202.3 4.35E-06 14/52 T.EC[160.03]C[160.03]HGDLLEC[160.03]ADDR.A "sp|P02768|ALBU_HUMAN,tr|B7WNR0|B7WNR0_HUMAN,tr|H0YA55|H0YA55_HUMAN,tr|A0A0C4DGB6|A0A0C4DGB6_HUMAN,tr|D6RHD5|D6RHD5_HUMAN,tr|C9JKR2|C9JKR2_HUMAN" 6 1748.6553 57.64 99738 12202 3 1748.65339 583.8924 Albumin OS=Homo sapiens OX=9606 GN=ALB PE=1 SV=2 4.1 2287.1 - 1.76E+06 - - - -1.066 - 2.455 0.672 - 230.7 1 1 0 -0.0019 14 0 0 0 9.51E+07 1.65E+06 - - - 8.4184 0.9998 221125_WJC_METTL3_EV_vs_WT_F07.12206.12206.4 2.35E-07 24/90 K.IFVGGIK[136.11]EDTEEHHLR[166.11].D "sp|Q32P51|RA1L2_HUMAN,sp|P09651|ROA1_HUMAN,sp|P22626|ROA2_HUMAN,tr|A0A7I2YQN4|A0A7I2YQN4_HUMAN,tr|A0A7I2YQX9|A0A7I2YQX9_HUMAN,tr|A0A7I2V4N0|A0A7I2V4N0_HUMAN,tr|A0A024RA28|A0A024RA28_HUMAN,tr|A0A7I2V4N1|A0A7I2V4N1_HUMAN,tr|A0A7I2V4I6|A0A7I2V4I6_HUMAN,tr|F8VZ49|F8VZ49_HUMAN,tr|A0A7I2V3R8|A0A7I2V3R8_HUMAN,tr|A0A087WUI2|A0A087WUI2_HUMAN,tr|A0A7I2V4S4|A0A7I2V4S4_HUMAN,tr|F8VTQ5|F8VTQ5_HUMAN,tr|F8W6I7|F8W6I7_HUMAN,tr|A0A7I2V2L6|A0A7I2V2L6_HUMAN,tr|A0A7I2V323|A0A7I2V323_HUMAN,tr|A0A7I2V3W0|A0A7I2V3W0_HUMAN,tr|A0A7I2V5U9|A0A7I2V5U9_HUMAN,tr|A0A2R8Y4L2|A0A2R8Y4L2_HUMAN,tr|A0A7I2V3P1|A0A7I2V3P1_HUMAN,tr|A0A7I2V3P7|A0A7I2V3P7_HUMAN" 22 1896.9813 0.39 99739 12206 4 1896.975786 475.2526 Heterogeneous nuclear ribonucleoprotein A1-like 2 OS=Homo sapiens OX=9606 GN=HNRNPA1L2 PE=2 SV=2 5.36 2287.6 - 2.93E+06 - - - -2.8967 - 3.804 0.577 - 502.3 1 2 1 -0.0055 16 0 0 0 1.33E+08 3.44E+08 - - - 4.7173 1 221125_WJC_METTL3_EV_vs_WT_F07.12207.12207.3 5.07E-10 20/60 K.IFVGGIK[136.11]EDTEEHHLR[166.11].D "sp|Q32P51|RA1L2_HUMAN,sp|P09651|ROA1_HUMAN,sp|P22626|ROA2_HUMAN,tr|A0A7I2YQN4|A0A7I2YQN4_HUMAN,tr|A0A7I2YQX9|A0A7I2YQX9_HUMAN,tr|A0A7I2V4N0|A0A7I2V4N0_HUMAN,tr|A0A024RA28|A0A024RA28_HUMAN,tr|A0A7I2V4N1|A0A7I2V4N1_HUMAN,tr|A0A7I2V4I6|A0A7I2V4I6_HUMAN,tr|F8VZ49|F8VZ49_HUMAN,tr|A0A7I2V3R8|A0A7I2V3R8_HUMAN,tr|A0A087WUI2|A0A087WUI2_HUMAN,tr|A0A7I2V4S4|A0A7I2V4S4_HUMAN,tr|F8VTQ5|F8VTQ5_HUMAN,tr|F8W6I7|F8W6I7_HUMAN,tr|A0A7I2V2L6|A0A7I2V2L6_HUMAN,tr|A0A7I2V323|A0A7I2V323_HUMAN,tr|A0A7I2V3W0|A0A7I2V3W0_HUMAN,tr|A0A7I2V5U9|A0A7I2V5U9_HUMAN,tr|A0A2R8Y4L2|A0A2R8Y4L2_HUMAN,tr|A0A7I2V3P1|A0A7I2V3P1_HUMAN,tr|A0A7I2V3P7|A0A7I2V3P7_HUMAN" 22 1896.9813 1.79 99740 12207 3 1896.985664 633.3344 Heterogeneous nuclear ribonucleoprotein A1-like 2 OS=Homo sapiens OX=9606 GN=HNRNPA1L2 PE=2 SV=2 5.36 2287.8 - 910366 - - - 2.3105 - 3.419 0.636 - 558.5 1 2 1 0.0044 16 0 0 0 5.06E+07 2.83E+07 - - - 8.7839 0.9995 221125_WJC_METTL3_EV_vs_WT_F07.12208.12208.3 6.07E-07 16/60 K.EAIESAIGGNAYQHSK.V sp|P63172|DYLT1_HUMAN 1 1673.8009 0.94 99741 12208 3 1673.792202 558.9409 Dynein light chain Tctex-type 1 OS=Homo sapiens OX=9606 GN=DYNLT1 PE=1 SV=1 5.4 2287.8 - 3.20E+06 - - - -5.2043 - 2.832 0.483 - 349.7 1 2 0 -0.0087 16 0 0 0 9.04E+07 9.59E+07 - - - 6.5936 1 221125_WJC_METTL3_EV_vs_WT_F07.12209.12209.2 0.000114 17/34 K.TAENATSGETLEENEAGD.- sp|Q9UQ80|PA2G4_HUMAN 1 1836.7497 - 99742 12209 2 1836.751837 919.3821 Proliferation-associated protein 2G4 OS=Homo sapiens OX=9606 GN=PA2G4 PE=1 SV=3 3.61 2287.9 - 1.93E+06 - - - 1.1499 - 3.133 0.585 - 729.6 1 2 0 0.0021 18 0 0 0 - - - - - 6.1688 0.9999 221125_WJC_METTL3_EV_vs_WT_F07.12215.12215.2 2.96E-08 15/24 R.DAVSNTTNQLESK[136.11].Q sp|Q86UP2|KTN1_HUMAN 1 1413.6827 2.05 99746 12215 2 1413.680995 707.8486 Kinectin OS=Homo sapiens OX=9606 GN=KTN1 PE=1 SV=1 4.37 2288.6 - 1.47E+06 - - - -1.2075 - 2.886 0.466 - 719.4 1 2 0 -0.0017 13 0 0 0 1.35E+08 6.58E+07 - - - 5.2025 0.9996 221125_WJC_METTL3_EV_vs_WT_F07.12221.12221.3 0.000229 13/40 R.K[136.11]K[136.11]LDASILEDR[166.11].D "sp|Q92785|REQU_HUMAN,tr|J3KMZ8|J3KMZ8_HUMAN" 2 1312.7561 1.2 99750 12221 3 1312.754108 438.5926 Zinc finger protein ubi-d4 OS=Homo sapiens OX=9606 GN=DPF2 PE=1 SV=2 6.12 2289.3 - 947210 - - - -1.506 - 2.438 0.414 - 366.3 1 2 1 -0.002 11 0 0 0 2.22E+07 1.86E+07 - - - 5.6868 1 221125_WJC_METTL3_EV_vs_WT_F07.12222.12222.3 1.82E-12 26/76 R.RGLGAGAGAGEESPATSLPR.M sp|O15173|PGRC2_HUMAN 1 1852.9391 0.78 99751 12222 3 1852.936481 618.6537 Membrane-associated progesterone receptor component 2 OS=Homo sapiens OX=9606 GN=PGRMC2 PE=1 SV=1 6.14 2289.4 - 653098 - - - -1.4339 - 4.402 0.631 - 872.5 1 2 0 -0.0027 20 0 0 0 2.66E+07 3.43E+07 - - - 9.1698 0.9982 221125_WJC_METTL3_EV_vs_WT_F07.12224.12224.3 2.28E-05 14/40 R.KKLDASILEDR.D "sp|Q92785|REQU_HUMAN,tr|J3KMZ8|J3KMZ8_HUMAN" 2 1286.7194 1.2 99753 12224 3 1286.718209 429.9137 Zinc finger protein ubi-d4 OS=Homo sapiens OX=9606 GN=DPF2 PE=1 SV=2 6.12 2289.6 - 747466 - - - -0.9373 - 2.524 0.254 - 397.7 1 2 1 -0.0012 11 0 0 0 2.22E+07 1.86E+07 - - - 4.0017 0.9999 221125_WJC_METTL3_EV_vs_WT_F07.12225.12225.3 3.60E-05 14/68 K.LSPPVASGGIPHQSPPTK[136.11].V sp|Q96T58|MINT_HUMAN 1 1776.9614 1.82 99754 12225 3 1776.959032 593.3277 Msx2-interacting protein OS=Homo sapiens OX=9606 GN=SPEN PE=1 SV=1 8.76 2289.8 - 600949 - - - -1.3236 - 2.674 0.403 - 226.2 1 2 0 -0.0024 18 0 0 0 4.32E+07 2.37E+07 - - - 5.4816 0.9999 221125_WJC_METTL3_EV_vs_WT_F07.12229.12229.3 0.000131 17/44 R.DNIQGITKPAIR.R sp|P62805|H4_HUMAN 1 1324.7463 1.1 99756 12229 3 1324.743751 442.5894 Histone H4 OS=Homo sapiens OX=9606 GN=H4C1 PE=1 SV=2 8.75 2290.3 - 7.86E+06 - - - -1.9234 - 2.673 0.445 - 492.2 1 2 0 -0.0025 12 0 0 0 2.13E+08 1.93E+08 - - - 6.2259 0.9993 221125_WJC_METTL3_EV_vs_WT_F07.12231.12231.3 0.00964 13/40 R.NSKIEISELNR.V sp|P04264|K2C1_HUMAN 1 1301.6939 911.08 99758 12231 3 1301.691545 434.9053 "Keratin, type II cytoskeletal 1 OS=Homo sapiens OX=9606 GN=KRT1 PE=1 SV=6" 6.14 2290.4 - 5.11E+06 - - - -1.8315 - 2.587 0.36 - 317.1 1 2 1 -0.0024 11 0 0 0 2.92E+08 3.20E+05 - - - 5.2532 0.9988 221125_WJC_METTL3_EV_vs_WT_F07.12232.12232.3 8.08E-05 17/56 K.NVSEELDR[166.11]TPPEVSK[136.11].K sp|Q15393|SF3B3_HUMAN 1 1716.8649 1.45 99759 12232 3 1716.861578 573.2956 Splicing factor 3B subunit 3 OS=Homo sapiens OX=9606 GN=SF3B3 PE=1 SV=4 4.41 2290.5 - 1.19E+06 - - - -1.9431 - 2.15 0.382 - 247.4 1 2 1 -0.0033 15 0 0 0 1.71E+08 1.18E+08 - - - 4.7954 0.9999 221125_WJC_METTL3_EV_vs_WT_F07.12233.12233.2 8.38E-05 24-Nov K.EHIAASVSIPSEK.Q "sp|P46379|BAG6_HUMAN,tr|F6UR09|F6UR09_HUMAN,tr|A0A7I2V508|A0A7I2V508_HUMAN,tr|F6U1F2|F6U1F2_HUMAN,tr|F6U341|F6U341_HUMAN,tr|F6WML8|F6WML8_HUMAN,tr|A0A0G2JJM1|A0A0G2JJM1_HUMAN,tr|X6REW1|X6REW1_HUMAN,tr|A0A7I2V3H1|A0A7I2V3H1_HUMAN,tr|A0A7P0MQS5|A0A7P0MQS5_HUMAN,tr|F6XTU0|F6XTU0_HUMAN,tr|F6X9W3|F6X9W3_HUMAN,tr|F6VEM6|F6VEM6_HUMAN,tr|A0A0G2JJR8|A0A0G2JJR8_HUMAN,tr|F6S6P2|F6S6P2_HUMAN,tr|F6TC96|F6TC96_HUMAN,tr|A0A0G2JL47|A0A0G2JL47_HUMAN,tr|A0A024RCR6|A0A024RCR6_HUMAN,tr|A0A0G2JK23|A0A0G2JK23_HUMAN,tr|A0A1B0GX79|A0A1B0GX79_HUMAN" 20 1366.7092 1.99 99760 12233 2 1366.707934 684.3619 Large proline-rich protein BAG6 OS=Homo sapiens OX=9606 GN=BAG6 PE=1 SV=2 5.4 2290.7 - 711550 - - - -0.9592 - 2.309 0.527 - 254.7 1 2 0 -0.0013 13 0 0 0 1.58E+07 7.97E+06 - - - 5.0807 1 221125_WJC_METTL3_EV_vs_WT_F07.12239.12239.3 1.01E-08 15/60 K.IFVGGIKEDTEEHHLR.D "sp|Q32P51|RA1L2_HUMAN,sp|P09651|ROA1_HUMAN,sp|P22626|ROA2_HUMAN,tr|A0A7I2YQN4|A0A7I2YQN4_HUMAN,tr|A0A7I2YQX9|A0A7I2YQX9_HUMAN,tr|A0A7I2V4N0|A0A7I2V4N0_HUMAN,tr|A0A024RA28|A0A024RA28_HUMAN,tr|A0A7I2V4N1|A0A7I2V4N1_HUMAN,tr|A0A7I2V4I6|A0A7I2V4I6_HUMAN,tr|F8VZ49|F8VZ49_HUMAN,tr|A0A7I2V3R8|A0A7I2V3R8_HUMAN,tr|A0A087WUI2|A0A087WUI2_HUMAN,tr|A0A7I2V4S4|A0A7I2V4S4_HUMAN,tr|F8VTQ5|F8VTQ5_HUMAN,tr|F8W6I7|F8W6I7_HUMAN,tr|A0A7I2V2L6|A0A7I2V2L6_HUMAN,tr|A0A7I2V323|A0A7I2V323_HUMAN,tr|A0A7I2V3W0|A0A7I2V3W0_HUMAN,tr|A0A7I2V5U9|A0A7I2V5U9_HUMAN,tr|A0A2R8Y4L2|A0A2R8Y4L2_HUMAN,tr|A0A7I2V3P1|A0A7I2V3P1_HUMAN,tr|A0A7I2V3P7|A0A7I2V3P7_HUMAN" 22 1878.9588 2.18 99764 12239 3 1878.958422 627.3269 Heterogeneous nuclear ribonucleoprotein A1-like 2 OS=Homo sapiens OX=9606 GN=HNRNPA1L2 PE=2 SV=2 5.36 2291.3 - 1.95E+06 - - - -0.207 - 3.135 0.612 - 291.8 1 2 1 -0.0004 16 0 0 0 6.16E+07 2.83E+07 - - - 8.2949 0.9979 221125_WJC_METTL3_EV_vs_WT_F07.12242.12242.2 0.00148 14/20 R.NSKIEISELNR.V sp|P04264|K2C1_HUMAN 1 1301.6939 999 99767 12242 2 1301.692139 651.8542 "Keratin, type II cytoskeletal 1 OS=Homo sapiens OX=9606 GN=KRT1 PE=1 SV=6" 6.14 2291.7 - 1.46E+06 - - - -1.3751 - 2.353 0.461 - 658.4 1 2 1 -0.0018 11 0 0 0 4.91E+07 0.00E+00 - - - 4.7602 0.9998 221125_WJC_METTL3_EV_vs_WT_F07.12243.12243.3 9.91E-06 18/68 R.DAPVHGSPTGPGAWTASK.L sp|Q9BRP1|PDD2L_HUMAN 1 1734.8325 2.59 99768 12243 3 1734.834872 579.2848 Programmed cell death protein 2-like OS=Homo sapiens OX=9606 GN=PDCD2L PE=1 SV=1 6.74 2291.8 - 870172 - - - 1.3396 - 3.086 0.293 - 475.3 1 2 0 0.0023 18 0 0 0 1.10E+08 4.24E+07 - - - 4.6121 0.9535 221125_WJC_METTL3_EV_vs_WT_F07.12252.12252.3 0.197 Sep-48 K.QK[136.11]EGNFDIVSGTR[166.11].Y "sp|O60762|DPM1_HUMAN,tr|A0A804HJ93|A0A804HJ93_HUMAN,tr|H0Y368|H0Y368_HUMAN,tr|A0A804HIK9|A0A804HIK9_HUMAN,tr|Q5QPK2|Q5QPK2_HUMAN" 5 1467.7437 0.99 99775 12252 3 1467.745191 490.2552 Dolichol-phosphate mannosyltransferase subunit 1 OS=Homo sapiens OX=9606 GN=DPM1 PE=1 SV=1 6.07 2292.8 - 796525 - - - 1.0322 - 1.747 0.161 - 88.8 1 2 1 0.0015 13 0 0 0 1.47E+07 1.49E+07 - - - 1.8472 0.9975 221125_WJC_METTL3_EV_vs_WT_F07.12257.12257.3 0.00212 Sep-48 K.QKEGNFDIVSGTR.Y "sp|O60762|DPM1_HUMAN,tr|A0A804HJ93|A0A804HJ93_HUMAN,tr|H0Y368|H0Y368_HUMAN,tr|A0A804HIK9|A0A804HIK9_HUMAN,tr|Q5QPK2|Q5QPK2_HUMAN" 5 1449.7212 0.99 99778 12257 3 1449.720394 484.2477 Dolichol-phosphate mannosyltransferase subunit 1 OS=Homo sapiens OX=9606 GN=DPM1 PE=1 SV=1 6.07 2293.4 - 1.21E+06 - - - -0.5601 - 1.725 0.335 - 80.5 1 2 1 -0.0008 13 0 0 0 1.47E+07 1.49E+07 - - - 3.753 0.9996 221125_WJC_METTL3_EV_vs_WT_F07.12258.12258.3 0.00577 13/60 R.LAQQMENRPSVQAALK.L "sp|Q9Y3Y2|CHTOP_HUMAN,tr|Q5T7Y7|Q5T7Y7_HUMAN,tr|A0A087X1B7|A0A087X1B7_HUMAN,tr|X6R700|X6R700_HUMAN" 4 1782.9411 1.75 99779 12258 3 1782.943832 595.321 Chromatin target of PRMT1 protein OS=Homo sapiens OX=9606 GN=CHTOP PE=1 SV=2 8.75 2293.6 - 766418 - - - 1.5592 - 2.487 0.316 - 172.7 1 2 0 0.0028 16 0 0 0 1.56E+07 8.88E+06 - - - 4.4 0.9972 221125_WJC_METTL3_EV_vs_WT_F07.12260.12260.3 0.00166 Dec-52 R.TRVTDSSVSVQLRE.- sp|Q6ZVX7|FBX50_HUMAN 1 1575.8216 10.11 99781 12260 3 1575.827275 526.2812 F-box only protein 50 OS=Homo sapiens OX=9606 GN=NCCRP1 PE=1 SV=1 5.91 2293.8 - 567315 - - - 3.5702 - 2.4 0.384 - 188.8 1 2 1 0.0056 14 0 0 0 9.54E+06 9.43E+05 - - - 5.1462 0.9999 221125_WJC_METTL3_EV_vs_WT_F07.12261.12261.3 0.000427 Nov-44 R.SSSSGHYVSWVK[136.11].R "sp|P54578|UBP14_HUMAN,tr|A6NJA2|A6NJA2_HUMAN" 2 1330.6397 0.91 99782 12261 3 1330.638064 444.5538 Ubiquitin carboxyl-terminal hydrolase 14 OS=Homo sapiens OX=9606 GN=USP14 PE=1 SV=3 8.33 2293.9 - 535932 - - - -1.2408 - 1.943 0.424 - 103.6 1 2 0 -0.0017 12 0 0 0 7.92E+06 8.75E+06 - - - 5.1079 0.9998 221125_WJC_METTL3_EV_vs_WT_F07.12264.12264.3 0.000187 13/56 K.NVSEELDRTPPEVSK.K sp|Q15393|SF3B3_HUMAN 1 1698.8424 1.45 99784 12264 3 1698.842393 567.2881 Splicing factor 3B subunit 3 OS=Homo sapiens OX=9606 GN=SF3B3 PE=1 SV=4 4.41 2294.3 - 4.89E+06 - - - -0.03 - 2.299 0.485 - 147.5 1 2 1 -0.0001 15 0 0 0 1.71E+08 1.18E+08 - - - 6.1195 0.9996 221125_WJC_METTL3_EV_vs_WT_F07.12269.12269.3 3.99E-05 Dec-36 R.DKHLEFSSLR.R "sp|Q09472|EP300_HUMAN,tr|A0A669KB12|A0A669KB12_HUMAN" 2 1230.6357 0.17 99788 12269 3 1230.63553 411.2192 Histone acetyltransferase p300 OS=Homo sapiens OX=9606 GN=EP300 PE=1 SV=2 6.75 2294.9 - 586408 - - - -0.1268 - 2.246 0.408 - 191.1 1 2 1 -0.0002 10 0 0 0 2.10E+07 1.22E+08 - - - 5.4518 1 221125_WJC_METTL3_EV_vs_WT_F07.12279.12279.2 7.63E-10 28-Dec K.NVSEELDR[166.11]TPPEVSK[136.11].K sp|Q15393|SF3B3_HUMAN 1 1716.8649 1.58 99796 12279 2 1716.868142 859.4397 Splicing factor 3B subunit 3 OS=Homo sapiens OX=9606 GN=SF3B3 PE=1 SV=4 4.41 2296.1 - 181100 - - - 1.8802 - 3.021 0.707 - 281.1 1 2 1 0.0032 15 0 0 0 5.64E+06 3.56E+06 - - - 6.98 0.9998 221125_WJC_METTL3_EV_vs_WT_F07.12283.12283.3 2.25E-12 19/64 K.VAQPTITDNK[136.11]DGTVTVR[166.11].Y "sp|P21333|FLNA_HUMAN,tr|Q60FE5|Q60FE5_HUMAN,tr|H0Y5F3|H0Y5F3_HUMAN" 3 1831.9759 8.34 99798 12283 3 1831.981297 611.6659 Filamin-A OS=Homo sapiens OX=9606 GN=FLNA PE=1 SV=4 5.93 2296.6 - 3.18E+06 - - - 2.9673 - 4.021 0.563 - 603.4 1 2 1 0.0054 17 0 0 0 4.44E+08 5.33E+07 - - - 8.3308 1 221125_WJC_METTL3_EV_vs_WT_F07.12284.12284.3 0.000575 17/68 R.DAPVHGSPTGPGAWTASK[136.11].L sp|Q9BRP1|PDD2L_HUMAN 1 1742.8467 2.41 99799 12284 3 1742.850123 581.9562 Programmed cell death protein 2-like OS=Homo sapiens OX=9606 GN=PDCD2L PE=1 SV=1 6.74 2296.7 - 1.30E+06 - - - 1.9365 - 3.362 0.493 - 451.8 1 2 0 0.0034 18 0 0 0 1.01E+08 4.20E+07 - - - 7.0549 0.962 221125_WJC_METTL3_EV_vs_WT_F07.12287.12287.4 0.018 Jul-66 K.YNPDKHYIYVVR.L sp|O00443|P3C2A_HUMAN 1 1565.7991 1.01 99802 12287 4 1565.80089 392.457 Phosphatidylinositol 4-phosphate 3-kinase C2 domain-containing subunit alpha OS=Homo sapiens OX=9606 GN=PIK3C2A PE=1 SV=2 8.44 2297 - 319061 - - - 1.1668 - 1.408 0.209 - 32.4 1 2 1 0.0018 12 0 0 0 4.33E+06 4.27E+06 - - - 1.1741 0.9999 221125_WJC_METTL3_EV_vs_WT_F07.12289.12289.3 0.000239 Oct-72 K.NVAAYTEQEEADSQGC[160.03]VQK[136.11].T "sp|Q13439|GOGA4_HUMAN,tr|H0Y6I0|H0Y6I0_HUMAN" 2 2133.9364 0.98 99804 12289 3 2133.93403 712.3194 Golgin subfamily A member 4 OS=Homo sapiens OX=9606 GN=GOLGA4 PE=1 SV=1 4 2297.3 - 213965 - - - -1.1233 - 1.764 0.477 - 91.4 1 2 0 -0.0024 19 0 0 0 2.36E+06 2.42E+06 - - - 5.2519 0.8495 221125_WJC_METTL3_EV_vs_WT_F07.12296.12296.3 0.0498 Oct-48 R.K[136.11]TEELEEESFPER[166.11].S "sp|Q9Y2W1|TR150_HUMAN,tr|A0A3B3ITZ9|A0A3B3ITZ9_HUMAN" 2 1639.7696 2.86 99809 12296 3 1639.769171 547.5971 Thyroid hormone receptor-associated protein 3 OS=Homo sapiens OX=9606 GN=THRAP3 PE=1 SV=2 4.21 2298.1 - 590635 - - - -0.2714 - 1.375 0.071 - 110.7 1 2 0 -0.0004 13 0 0 0 1.38E+10 4.81E+09 - - - 0.1949 1 221125_WJC_METTL3_EV_vs_WT_F07.12298.12298.3 0.000196 16/48 K.K[136.11]PLPDHVSIVEPK[136.11].D "sp|P23396|RS3_HUMAN,tr|H0YEU2|H0YEU2_HUMAN,tr|E9PSF4|E9PSF4_HUMAN,tr|E9PL09|E9PL09_HUMAN,tr|E9PPU1|E9PPU1_HUMAN" 5 1473.8526 0.71 99811 12298 3 1473.85119 492.2915 40S ribosomal protein S3 OS=Homo sapiens OX=9606 GN=RPS3 PE=1 SV=2 6.75 2298.3 - 461792 - - - -0.9669 - 2.734 0.46 - 306.8 1 2 0 -0.0014 13 0 0 0 4.67E+07 6.61E+07 - - - 6.3951 0.9964 221125_WJC_METTL3_EV_vs_WT_F07.12299.12299.3 6.09E-05 15/48 S.GFSLEDPQTHSNR[166.11].L sp|P08238|HS90B_HUMAN 1 1496.6883 1.97 99812 12299 3 1496.689803 499.9034 Heat shock protein HSP 90-beta OS=Homo sapiens OX=9606 GN=HSP90AB1 PE=1 SV=4 5.32 2298.5 - 451090 - - - 0.9775 - 2.571 0.479 - 202.4 1 1 0 0.0015 13 0 0 0 1.97E+07 1.00E+07 - - - 6.4402 0.9996 221125_WJC_METTL3_EV_vs_WT_F07.12305.12305.3 0.0346 Dec-52 K.GAVDGGLSIPHSTK.R "sp|P46777|RL5_HUMAN,tr|A0A2R8Y6J3|A0A2R8Y6J3_HUMAN,tr|Q5T7N0|Q5T7N0_HUMAN" 3 1337.6939 0.76 99816 12305 3 1337.693904 446.9053 60S ribosomal protein L5 OS=Homo sapiens OX=9606 GN=RPL5 PE=1 SV=3 6.74 2299.2 - 1.51E+06 - - - -0.0187 - 1.878 0.333 - 150 1 2 0 0 14 0 0 0 3.01E+07 3.93E+07 - - - 3.9274 0.9998 221125_WJC_METTL3_EV_vs_WT_F07.12306.12306.3 0.00211 Nov-52 K.GAVDGGLSIPHSTK[136.11].R "sp|P46777|RL5_HUMAN,tr|A0A2R8Y6J3|A0A2R8Y6J3_HUMAN,tr|Q5T7N0|Q5T7N0_HUMAN" 3 1345.7081 0.67 99817 12306 3 1345.707022 449.5767 60S ribosomal protein L5 OS=Homo sapiens OX=9606 GN=RPL5 PE=1 SV=3 6.74 2299.3 - 1.58E+06 - - - -0.8226 - 1.818 0.414 - 146.9 1 2 0 -0.0011 14 0 0 0 3.02E+07 4.54E+07 - - - 4.7439 1 221125_WJC_METTL3_EV_vs_WT_F07.12308.12308.3 4.61E-08 18/48 R.GEC[160.03]QAC[160.03]DQLHFC[160.03]R[166.11].R sp|Q96H79|ZCCHL_HUMAN 1 1689.6686 1.03 99819 12308 3 1689.668185 564.2301 Zinc finger CCCH-type antiviral protein 1-like OS=Homo sapiens OX=9606 GN=ZC3HAV1L PE=1 SV=2 5.32 2299.5 - 797557 - - - -0.216 - 3.268 0.702 - 654.4 1 2 0 -0.0004 13 0 0 0 1.51E+07 1.47E+07 - - - 9.5772 1 221125_WJC_METTL3_EV_vs_WT_F07.12313.12313.3 2.12E-08 14/72 R.ELHTADSVVNGSAQADVPK.E "sp|Q96EK9|KTI12_HUMAN,tr|A0A3B3IU88|A0A3B3IU88_HUMAN" 2 1936.949 0.42 99824 12313 3 1936.950415 646.657 Protein KTI12 homolog OS=Homo sapiens OX=9606 GN=KTI12 PE=1 SV=1 4.54 2300.1 - 226608 - - - 0.713 - 2.734 0.572 - 212.8 1 2 0 0.0014 19 0 0 0 4.35E+06 1.03E+07 - - - 7.3878 0.9998 221125_WJC_METTL3_EV_vs_WT_F07.12319.12319.3 0.000529 Nov-48 K.GHSLSDGLEEVQK[136.11].A "sp|O75431|MTX2_HUMAN,tr|C9JAZ1|C9JAZ1_HUMAN,tr|C9JNK6|C9JNK6_HUMAN" 3 1405.6929 1.36 99828 12319 3 1405.691866 469.5716 Metaxin-2 OS=Homo sapiens OX=9606 GN=MTX2 PE=1 SV=1 4.65 2300.7 - 1.34E+06 - - - -0.7164 - 2.264 0.362 - 262.1 1 2 0 -0.001 13 0 0 0 4.82E+07 3.55E+07 - - - 4.7911 1 221125_WJC_METTL3_EV_vs_WT_F07.12321.12321.2 1.44E-07 16/34 R.LLEGEDAHLSSQQASGQS.Y sp|P08779|K1C16_HUMAN 1 1855.8548 - 99830 12321 2 1855.856414 928.9347 "Keratin, type I cytoskeletal 16 OS=Homo sapiens OX=9606 GN=KRT16 PE=1 SV=4" 4.13 2300.9 - 747188 - - - 0.8702 - 3.238 0.628 - 553.4 1 1 0 0.0016 18 0 0 0 - - - - - 6.5676 0.9999 221125_WJC_METTL3_EV_vs_WT_F07.12327.12327.3 3.70E-05 Dec-52 K.ITNDFYPEEDGKTK.G "sp|P55884|EIF3B_HUMAN,tr|C9JZG1|C9JZG1_HUMAN" 2 1655.7679 1.52 99834 12327 3 1655.766901 552.9299 Eukaryotic translation initiation factor 3 subunit B OS=Homo sapiens OX=9606 GN=EIF3B PE=1 SV=3 4.32 2301.6 - 2.67E+06 - - - -0.5925 - 2.437 0.507 - 189.2 1 2 1 -0.001 14 0 0 0 6.31E+07 4.15E+07 - - - 6.5595 0.9998 221125_WJC_METTL3_EV_vs_WT_F07.12329.12329.3 2.87E-05 14/48 K.TSLTVADKIEDQK.K "sp|P52732|KIF11_HUMAN,tr|A0A7I2V3A9|A0A7I2V3A9_HUMAN" 2 1446.7566 4.77 99836 12329 3 1446.756761 483.2595 Kinesin-like protein KIF11 OS=Homo sapiens OX=9606 GN=KIF11 PE=1 SV=2 4.56 2301.7 - 1.48E+06 - - - 0.1189 - 2.692 0.429 - 297.5 1 2 1 0.0002 13 0 0 0 4.49E+07 9.41E+06 - - - 6.0078 0.984 221125_WJC_METTL3_EV_vs_WT_F07.12331.12331.3 0.0834 Nov-48 K.ASVSITFDNSDK[136.11]K[136.11].Q sp|O95347|SMC2_HUMAN 1 1426.7275 1.22 99838 12331 3 1426.721648 476.5831 Structural maintenance of chromosomes protein 2 OS=Homo sapiens OX=9606 GN=SMC2 PE=1 SV=2 6 2301.9 - 839506 - - - -4.0835 - 1.839 0.238 - 103.9 1 2 0 -0.0058 13 0 0 0 1.98E+07 1.62E+07 - - - 2.8436 0.8149 221125_WJC_METTL3_EV_vs_WT_F07.12332.12332.3 0.0287 Nov-44 R.QRPSEIKDYSPY.F sp|P08779|K1C16_HUMAN 1 1481.7151 6.3 99839 12332 3 1481.716131 494.9123 "Keratin, type I cytoskeletal 16 OS=Homo sapiens OX=9606 GN=KRT16 PE=1 SV=4" 6.07 2302 - 818174 - - - 0.7242 - 1.765 0.337 - 148.4 1 1 1 0.0011 12 0 0 0 1.80E+07 2.86E+06 - - - 3.8717 1 221125_WJC_METTL3_EV_vs_WT_F07.12335.12335.3 2.72E-09 20/96 R.VANTSTQTMGPRPAAAAAAATPAVR.T "sp|P11940|PABP1_HUMAN,tr|H0YAS6|H0YAS6_HUMAN,tr|H0YB75|H0YB75_HUMAN,tr|A0A7I2YQE4|A0A7I2YQE4_HUMAN,tr|H0YAW6|H0YAW6_HUMAN,tr|A0A7I2V649|A0A7I2V649_HUMAN,tr|E7ERJ7|E7ERJ7_HUMAN,tr|A0A7I2YQ88|A0A7I2YQ88_HUMAN,tr|A0A087WTT1|A0A087WTT1_HUMAN,tr|A0A7I2YQ90|A0A7I2YQ90_HUMAN,tr|A0A7I2V4N4|A0A7I2V4N4_HUMAN,tr|E7EQV3|E7EQV3_HUMAN" 12 2380.2281 1.98 99842 12335 3 2380.230349 794.4167 Polyadenylate-binding protein 1 OS=Homo sapiens OX=9606 GN=PABPC1 PE=1 SV=2 12 2302.4 - 442458 - - - 0.9339 - 4.012 0.638 - 498.4 1 2 0 0.0022 25 0 0 0 9.05E+06 4.56E+06 - - - 8.8487 1 221125_WJC_METTL3_EV_vs_WT_F07.12336.12336.3 2.95E-08 15/96 R.VANTSTQTMGPR[166.11]PAAAAAAATPAVR[166.11].T "sp|P11940|PABP1_HUMAN,tr|H0YAS6|H0YAS6_HUMAN,tr|H0YB75|H0YB75_HUMAN,tr|A0A7I2YQE4|A0A7I2YQE4_HUMAN,tr|H0YAW6|H0YAW6_HUMAN,tr|A0A7I2V649|A0A7I2V649_HUMAN,tr|E7ERJ7|E7ERJ7_HUMAN,tr|A0A7I2YQ88|A0A7I2YQ88_HUMAN,tr|A0A087WTT1|A0A087WTT1_HUMAN,tr|A0A7I2YQ90|A0A7I2YQ90_HUMAN,tr|A0A7I2V4N4|A0A7I2V4N4_HUMAN,tr|E7EQV3|E7EQV3_HUMAN" 12 2400.2447 2.09 99843 12336 3 2400.239845 801.0888 Polyadenylate-binding protein 1 OS=Homo sapiens OX=9606 GN=PABPC1 PE=1 SV=2 12 2302.5 - 245629 - - - -2.0085 - 3.209 0.613 - 213.6 1 2 0 -0.0048 25 0 0 0 9.53E+06 4.56E+06 - - - 8.0555 0.9999 221125_WJC_METTL3_EV_vs_WT_F07.12339.12339.3 0.00136 Dec-48 K.GHSLSDGLEEVQK.A "sp|O75431|MTX2_HUMAN,tr|C9JAZ1|C9JAZ1_HUMAN,tr|C9JNK6|C9JNK6_HUMAN" 3 1397.6787 1.36 99844 12339 3 1397.678139 466.9002 Metaxin-2 OS=Homo sapiens OX=9606 GN=MTX2 PE=1 SV=1 4.65 2302.9 - 3.26E+06 - - - -0.3821 - 2.303 0.396 - 301.5 1 2 0 -0.0005 13 0 0 0 4.72E+07 3.46E+07 - - - 5.2167 0.9531 221125_WJC_METTL3_EV_vs_WT_F07.12341.12341.3 1.20E-05 13/52 A.SSEAPPLINEDVKR.T "sp|P04843|RPN1_HUMAN,tr|F8WF32|F8WF32_HUMAN" 2 1553.8049 1.23 99846 12341 3 1553.800623 518.9423 Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit 1 OS=Homo sapiens OX=9606 GN=RPN1 PE=1 SV=1 4.68 2303.1 - 2.99E+06 - - - -2.7758 - 2.224 0.374 - 173.1 1 1 0 -0.0043 14 0 0 0 2.62E+08 2.13E+08 - - - 4.8327 0.9998 221125_WJC_METTL3_EV_vs_WT_F07.12343.12343.4 0.00041 20/84 R.QASTLIDRPAPHFER.T "sp|O43491|E41L2_HUMAN,tr|A0A2R8Y5B3|A0A2R8Y5B3_HUMAN,tr|E9PII3|E9PII3_HUMAN,tr|E9PHY5|E9PHY5_HUMAN,tr|H0Y5B0|H0Y5B0_HUMAN,tr|E9PK52|E9PK52_HUMAN" 6 1736.8958 0.68 99848 12343 4 1736.899416 435.2312 Band 4.1-like protein 2 OS=Homo sapiens OX=9606 GN=EPB41L2 PE=1 SV=1 6.75 2303.3 - 875659 - - - 2.0721 - 3.211 0.385 - 407.7 1 2 0 0.0036 15 0 0 0 1.39E+07 2.04E+07 - - - 2.9935 1 221125_WJC_METTL3_EV_vs_WT_F07.12345.12345.3 4.82E-07 17/56 R.QASTLIDR[166.11]PAPHFER[166.11].T "sp|O43491|E41L2_HUMAN,tr|A0A2R8Y5B3|A0A2R8Y5B3_HUMAN,tr|E9PII3|E9PII3_HUMAN,tr|E9PHY5|E9PHY5_HUMAN,tr|H0Y5B0|H0Y5B0_HUMAN,tr|E9PK52|E9PK52_HUMAN" 6 1756.9124 1.74 99850 12345 3 1756.913002 586.6447 Band 4.1-like protein 2 OS=Homo sapiens OX=9606 GN=EPB41L2 PE=1 SV=1 6.75 2303.5 - 549796 - - - 0.3671 - 2.729 0.522 - 530.2 1 2 0 0.0006 15 0 0 0 1.57E+07 8.99E+06 - - - 6.9792 1 221125_WJC_METTL3_EV_vs_WT_F07.12346.12346.3 2.30E-10 18/68 K.YPPQEAEQLSHQAAPGPR.R "sp|O94761|RECQ4_HUMAN,tr|A0A087X072|A0A087X072_HUMAN,tr|V9GZ64|V9GZ64_HUMAN" 3 1974.9548 0.21 99851 12346 3 1974.955591 659.3255 ATP-dependent DNA helicase Q4 OS=Homo sapiens OX=9606 GN=RECQL4 PE=1 SV=2 5.4 2303.6 - 414044 - - - 0.4066 - 3.083 0.598 - 428.6 1 2 0 0.0008 18 0 0 0 7.34E+06 3.52E+07 - - - 8.0105 0.9894 221125_WJC_METTL3_EV_vs_WT_F07.12347.12347.3 0.198 Nov-52 K.ATIAGGGVIPHIHK[136.11].S "sp|P0C0S5|H2AZ_HUMAN,sp|Q71UI9|H2AV_HUMAN" 2 1377.7972 1.33 99852 12347 3 1377.797655 460.273 Histone H2A.Z OS=Homo sapiens OX=9606 GN=H2AZ1 PE=1 SV=2 8.81 2303.7 - 399270 - - - 0.3164 - 2.089 0.114 - 142.9 1 2 0 0.0004 14 0 0 0 7.77E+08 5.86E+08 - - - 1.7686 1 221125_WJC_METTL3_EV_vs_WT_F07.12354.12354.3 2.62E-11 28/104 A.GGAVAVSAAPGSAAPAAGSAPAAAEEK.K "sp|P05387|RLA2_HUMAN,tr|H0YDD8|H0YDD8_HUMAN" 2 2235.1131 1.74 99857 12354 3 2235.112971 746.045 60S acidic ribosomal protein P2 OS=Homo sapiens OX=9606 GN=RPLP2 PE=1 SV=1 4.53 2304.6 - 1.34E+06 - - - -0.0752 - 4.566 0.631 - 700.9 1 1 0 -0.0002 27 0 0 0 1.76E+07 1.01E+07 - - - 9.0688 0.9999 221125_WJC_METTL3_EV_vs_WT_F07.12356.12356.3 1.70E-08 17/64 K.VYVGNLGNNGNKTELER.A "sp|P84103|SRSF3_HUMAN,tr|A0A087X2D0|A0A087X2D0_HUMAN" 2 1875.9439 1.69 99859 12356 3 1875.946351 626.3219 Serine\arginine-rich splicing factor 3 OS=Homo sapiens OX=9606 GN=SRSF3 PE=1 SV=1 6.11 2304.8 - 1.02E+06 - - - 1.3124 - 3.289 0.587 - 290.4 1 2 1 0.0025 17 0 0 0 1.07E+08 6.31E+07 - - - 8.0916 0.9999 221125_WJC_METTL3_EV_vs_WT_F07.12357.12357.3 0.000131 Oct-68 K.VTDTQEAEC[160.03]AGPPVPDPK[136.11].N "sp|Q99614|TTC1_HUMAN,tr|A0A804HKC5|A0A804HKC5_HUMAN,tr|A0A804HL30|A0A804HL30_HUMAN,tr|A0A804HHT7|A0A804HHT7_HUMAN,tr|A0A804HKI4|A0A804HKI4_HUMAN" 5 1917.887 1.02 99860 12357 3 1917.887717 640.3029 Tetratricopeptide repeat protein 1 OS=Homo sapiens OX=9606 GN=TTC1 PE=1 SV=1 3.92 2305 - 482038 - - - 0.3957 - 1.765 0.501 - 78.8 1 2 0 0.0008 18 0 0 0 3.40E+07 3.33E+07 - - - 5.5402 1 221125_WJC_METTL3_EV_vs_WT_F07.12358.12358.2 2.34E-08 28-Nov K.TGQPEELVSC[160.03]SDC[160.03]GR[166.11].S "sp|Q92785|REQU_HUMAN,tr|J3KMZ8|J3KMZ8_HUMAN" 2 1703.7119 1.12 99861 12358 2 1703.714261 852.8632 Zinc finger protein ubi-d4 OS=Homo sapiens OX=9606 GN=DPF2 PE=1 SV=2 4.14 2305.1 - 205013 - - - 1.4128 - 2.388 0.639 - 366.6 1 2 0 0.0024 15 0 0 0 6.28E+07 5.63E+07 - - - 5.9 0.9573 221125_WJC_METTL3_EV_vs_WT_F07.12361.12361.3 0.151 Sep-52 R.SPSK[136.11]PLPEVTDEYK[136.11].N "sp|P05455|LA_HUMAN,tr|E9PGX9|E9PGX9_HUMAN,tr|E9PFL9|E9PFL9_HUMAN,tr|E7ERC4|E7ERC4_HUMAN" 4 1604.8269 1.24 99863 12361 3 1604.825836 535.9496 Lupus La protein OS=Homo sapiens OX=9606 GN=SSB PE=1 SV=2 4.68 2305.4 - 511237 - - - -0.6343 - 1.704 0.089 - 72.9 1 2 0 -0.001 14 0 0 0 1.48E+09 1.19E+09 - - - 0.9484 0.9905 221125_WJC_METTL3_EV_vs_WT_F07.12363.12363.3 0.0847 15/52 A.SSEAPPLINEDVK[136.11]R[166.11].T "sp|P04843|RPN1_HUMAN,tr|F8WF32|F8WF32_HUMAN" 2 1571.8274 1.2 99864 12363 3 1571.826573 524.9497 Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit 1 OS=Homo sapiens OX=9606 GN=RPN1 PE=1 SV=1 4.68 2305.7 - 5.67E+06 - - - -0.53 - 2.687 0.369 - 273.8 1 1 0 -0.0008 14 0 0 0 2.62E+08 2.19E+08 - - - 5.2805 0.9999 221125_WJC_METTL3_EV_vs_WT_F07.12365.12365.3 6.17E-07 16/64 K.VYVGNLGNNGNK[136.11]TELER[166.11].A "sp|P84103|SRSF3_HUMAN,tr|A0A087X2D0|A0A087X2D0_HUMAN" 2 1893.9664 1.69 99866 12365 3 1893.96588 632.3294 Serine\arginine-rich splicing factor 3 OS=Homo sapiens OX=9606 GN=SRSF3 PE=1 SV=1 6.11 2305.8 - 1.72E+06 - - - -0.2529 - 3.256 0.587 - 243.9 1 2 1 -0.0005 17 0 0 0 1.07E+08 6.31E+07 - - - 8.0666 0.9999 221125_WJC_METTL3_EV_vs_WT_F07.12366.12366.3 0.000831 14/56 R.QASTLIDRPAPHFER.T "sp|O43491|E41L2_HUMAN,tr|A0A2R8Y5B3|A0A2R8Y5B3_HUMAN,tr|E9PII3|E9PII3_HUMAN,tr|E9PHY5|E9PHY5_HUMAN,tr|H0Y5B0|H0Y5B0_HUMAN,tr|E9PK52|E9PK52_HUMAN" 6 1736.8958 1.49 99867 12366 3 1736.894711 579.9725 Band 4.1-like protein 2 OS=Homo sapiens OX=9606 GN=EPB41L2 PE=1 SV=1 6.75 2305.9 - 876604 - - - -0.6368 - 2.568 0.411 - 300.8 1 2 0 -0.0011 15 0 0 0 1.34E+07 8.99E+06 - - - 5.5829 1 221125_WJC_METTL3_EV_vs_WT_F07.12367.12367.2 9.60E-10 17/24 R.K[136.11]TEELEEESFPER[166.11].S "sp|Q9Y2W1|TR150_HUMAN,tr|A0A3B3ITZ9|A0A3B3ITZ9_HUMAN" 2 1639.7696 2.79 99868 12367 2 1639.770079 820.8921 Thyroid hormone receptor-associated protein 3 OS=Homo sapiens OX=9606 GN=THRAP3 PE=1 SV=2 4.21 2306 - 722455 - - - 0.2824 - 3.479 0.688 - 1217.3 1 2 0 0.0005 13 0 0 0 1.72E+09 6.17E+08 - - - 7.3222 0.9989 221125_WJC_METTL3_EV_vs_WT_F07.12368.12368.3 0.0116 15/48 K.TSLTVADK[136.11]IEDQK[136.11].K "sp|P52732|KIF11_HUMAN,tr|A0A7I2V3A9|A0A7I2V3A9_HUMAN" 2 1462.785 5.03 99869 12368 3 1462.781549 488.6023 Kinesin-like protein KIF11 OS=Homo sapiens OX=9606 GN=KIF11 PE=1 SV=2 4.56 2306.1 - 712327 - - - -2.3517 - 2.632 0.36 - 322.7 1 2 1 -0.0034 13 0 0 0 4.43E+07 8.81E+06 - - - 5.1765 1 221125_WJC_METTL3_EV_vs_WT_F07.12369.12369.2 6.29E-07 13/24 K.GHSLSDGLEEVQK.A "sp|O75431|MTX2_HUMAN,tr|C9JAZ1|C9JAZ1_HUMAN,tr|C9JNK6|C9JNK6_HUMAN" 3 1397.6787 1.52 99870 12369 2 1397.679549 699.8466 Metaxin-2 OS=Homo sapiens OX=9606 GN=MTX2 PE=1 SV=1 4.65 2306.2 - 628981 - - - 0.6268 - 2.772 0.617 - 382.5 1 2 0 0.0009 13 0 0 0 8.01E+06 5.28E+06 - - - 6.2146 1 221125_WJC_METTL3_EV_vs_WT_F07.12371.12371.2 2.61E-05 20/36 Q.ATQLQTTQSVEGATGSAVK.S "sp|Q14157|UBP2L_HUMAN,tr|F8W726|F8W726_HUMAN" 2 1875.9538 3.1 99872 12371 2 1875.949454 938.9842 Ubiquitin-associated protein 2-like OS=Homo sapiens OX=9606 GN=UBAP2L PE=1 SV=2 6.05 2306.5 - 440528 - - - -2.3087 - 3.698 0.63 - 1304.8 1 1 0 -0.0043 19 0 0 0 1.31E+07 4.24E+06 - - - 6.9081 0.9812 221125_WJC_METTL3_EV_vs_WT_F07.12373.12373.2 0.000694 26-Jun K.ITNDFYPEEDGKTK.G "sp|P55884|EIF3B_HUMAN,tr|C9JZG1|C9JZG1_HUMAN" 2 1655.7679 2 99874 12373 2 1655.769732 828.8912 Eukaryotic translation initiation factor 3 subunit B OS=Homo sapiens OX=9606 GN=EIF3B PE=1 SV=3 4.32 2306.7 - 206348 - - - 1.1173 - 1.356 0.324 - 68.5 1 2 1 0.0019 14 0 0 0 1.34E+06 6.70E+05 - - - 2.1977 1 221125_WJC_METTL3_EV_vs_WT_F07.12375.12375.3 3.41E-05 17/48 R.KTEELEEESFPER.S "sp|Q9Y2W1|TR150_HUMAN,tr|A0A3B3ITZ9|A0A3B3ITZ9_HUMAN" 2 1621.7471 2.85 99875 12375 3 1621.747952 541.5897 Thyroid hormone receptor-associated protein 3 OS=Homo sapiens OX=9606 GN=THRAP3 PE=1 SV=2 4.21 2306.9 - 3.70E+07 - - - 0.497 - 3.188 0.557 - 476.3 1 2 0 0.0008 13 0 0 0 1.37E+10 4.80E+09 - - - 7.8932 1 221125_WJC_METTL3_EV_vs_WT_F07.12377.12377.2 3.78E-06 17/24 R.KTEELEEESFPER.S "sp|Q9Y2W1|TR150_HUMAN,tr|A0A3B3ITZ9|A0A3B3ITZ9_HUMAN" 2 1621.7471 2.78 99876 12377 2 1621.746754 811.8808 Thyroid hormone receptor-associated protein 3 OS=Homo sapiens OX=9606 GN=THRAP3 PE=1 SV=2 4.21 2307.2 - 3.04E+06 - - - -0.2417 - 3.534 0.623 - 1143.8 1 2 0 -0.0004 13 0 0 0 1.55E+09 5.57E+08 - - - 6.8824 0.9984 221125_WJC_METTL3_EV_vs_WT_F07.12378.12378.3 6.17E-07 24/104 A.GGAVAVSAAPGSAAPAAGSAPAAAEEK[136.11].K "sp|P05387|RLA2_HUMAN,tr|H0YDD8|H0YDD8_HUMAN" 2 2243.1273 1.74 99877 12378 3 2243.126678 748.7164 60S acidic ribosomal protein P2 OS=Homo sapiens OX=9606 GN=RPLP2 PE=1 SV=1 4.53 2307.3 - 1.12E+06 - - - -0.2947 - 3.95 0.522 - 475.8 1 1 0 -0.0007 27 0 0 0 1.76E+07 1.01E+07 - - - 7.52 0.9994 221125_WJC_METTL3_EV_vs_WT_F07.12382.12382.3 0.0106 14/40 K.HFTILDAPGHK.S "sp|Q8IYD1|ERF3B_HUMAN,sp|P15170|ERF3A_HUMAN,tr|H3BR35|H3BR35_HUMAN,tr|H3BSV8|H3BSV8_HUMAN" 4 1234.6459 0.53 99881 12382 3 1234.645529 412.5559 Eukaryotic peptide chain release factor GTP-binding subunit ERF3B OS=Homo sapiens OX=9606 GN=GSPT2 PE=1 SV=2 6.92 2307.8 - 640895 - - - -0.2649 - 1.581 0.346 - 244 1 2 0 -0.0003 11 0 0 0 2.35E+07 4.45E+07 - - - 3.6987 0.9971 221125_WJC_METTL3_EV_vs_WT_F07.12383.12383.3 1.23E-06 17/72 Q.ATQLQTTQSVEGATGSAVK[136.11].S "sp|Q14157|UBP2L_HUMAN,tr|F8W726|F8W726_HUMAN" 2 1883.968 19.86 99882 12383 3 1883.967615 628.9966 Ubiquitin-associated protein 2-like OS=Homo sapiens OX=9606 GN=UBAP2L PE=1 SV=2 6.05 2307.9 - 640506 - - - -0.1964 - 3.115 0.472 - 437.2 1 1 0 -0.0004 19 0 0 0 1.03E+08 5.21E+06 - - - 6.5937 0.9998 221125_WJC_METTL3_EV_vs_WT_F07.12384.12384.2 0.000541 26-Oct R.ESEGFEEHVPSDNS.- sp|P62699|YPEL5_HUMAN 1 1561.6169 - 99883 12384 2 1561.615181 781.8157 Protein yippee-like 5 OS=Homo sapiens OX=9606 GN=YPEL5 PE=1 SV=1 3.9 2308 - 533798 - - - -1.0752 - 1.642 0.524 - 258.6 1 2 0 -0.0017 14 0 0 0 - - - - - 4.1552 1 221125_WJC_METTL3_EV_vs_WT_F07.12386.12386.2 1.61E-07 20/36 Q.ATQLQTTQSVEGATGSAVK[136.11].S "sp|Q14157|UBP2L_HUMAN,tr|F8W726|F8W726_HUMAN" 2 1883.968 3.1 99885 12386 2 1883.968189 942.9913 Ubiquitin-associated protein 2-like OS=Homo sapiens OX=9606 GN=UBAP2L PE=1 SV=2 6.05 2308.3 - 434097 - - - 0.1083 - 3.83 0.663 - 1428.1 1 1 0 0.0002 19 0 0 0 1.31E+07 4.24E+06 - - - 7.2393 0.9933 221125_WJC_METTL3_EV_vs_WT_F07.12388.12388.2 2.31E-08 26-Dec A.SSEAPPLINEDVK[136.11]R[166.11].T "sp|P04843|RPN1_HUMAN,tr|F8WF32|F8WF32_HUMAN" 2 1571.8274 1.35 99887 12388 2 1571.828589 786.921 Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit 1 OS=Homo sapiens OX=9606 GN=RPN1 PE=1 SV=1 4.68 2308.6 - 343738 - - - 0.7526 - 2.324 0.566 - 272.7 1 1 0 0.0012 14 0 0 0 1.09E+07 8.07E+06 - - - 5.3373 1 221125_WJC_METTL3_EV_vs_WT_F07.12389.12389.2 5.19E-09 Oct-34 K.VTDTQEAEC[160.03]AGPPVPDPK.N "sp|Q99614|TTC1_HUMAN,tr|A0A804HKC5|A0A804HKC5_HUMAN,tr|A0A804HL30|A0A804HL30_HUMAN,tr|A0A804HHT7|A0A804HHT7_HUMAN,tr|A0A804HKI4|A0A804HKI4_HUMAN" 5 1909.8728 0.87 99888 12389 2 1909.872963 955.9437 Tetratricopeptide repeat protein 1 OS=Homo sapiens OX=9606 GN=TTC1 PE=1 SV=1 3.92 2308.7 - 139929 - - - 0.1073 - 2.32 0.702 - 141 1 2 0 0.0002 18 0 0 0 6.32E+06 7.28E+06 - - - 6.2949 0.9999 221125_WJC_METTL3_EV_vs_WT_F07.12392.12392.3 8.73E-06 14/48 R.TNEKVELQELNDR.F "sp|P08670|VIME_HUMAN,sp|P17661|DESM_HUMAN,tr|B0YJC4|B0YJC4_HUMAN,tr|A0A1B0GTT5|A0A1B0GTT5_HUMAN" 4 1586.79 1.98 99889 12392 3 1586.789397 529.9373 Vimentin OS=Homo sapiens OX=9606 GN=VIM PE=1 SV=4 4.41 2309.1 - 7.61E+06 - - - -0.3888 - 2.863 0.514 - 378.2 1 2 1 -0.0006 13 0 0 0 4.29E+09 2.17E+09 - - - 7.1223 0.9996 221125_WJC_METTL3_EV_vs_WT_F07.12393.12393.3 0.0153 14/40 R.RIDISPSTFRK.H "sp|Q9Y2W1|TR150_HUMAN,tr|A0A3B3ITZ9|A0A3B3ITZ9_HUMAN" 2 1318.7357 1.67 99890 12393 3 1318.736682 440.5859 Thyroid hormone receptor-associated protein 3 OS=Homo sapiens OX=9606 GN=THRAP3 PE=1 SV=2 10.84 2309.1 - 3.23E+06 - - - 0.7189 - 2.271 0.274 - 350.9 1 2 0 0.0009 11 0 0 0 1.07E+08 6.43E+07 - - - 3.9247 0.9997 221125_WJC_METTL3_EV_vs_WT_F07.12397.12397.3 0.000649 17/72 K.LSPQGYASPVSQSPQTSSK.Q "sp|P43694|GATA4_HUMAN,tr|B3KUF4|B3KUF4_HUMAN,tr|A0A087WZ09|A0A087WZ09_HUMAN" 3 1947.9538 2.97 99894 12397 3 1947.960459 650.3252 Transcription factor GATA-4 OS=Homo sapiens OX=9606 GN=GATA4 PE=1 SV=2 8.59 2309.4 - 1.06E+06 - - - 3.4262 - 2.744 0.437 - 295.2 1 2 0 0.0067 19 0 0 0 1.69E+07 5.69E+06 - - - 5.8902 0.9999 221125_WJC_METTL3_EV_vs_WT_F07.12398.12398.3 0.0044 14/40 K.HFTILDAPGHK[136.11].S "sp|Q8IYD1|ERF3B_HUMAN,sp|P15170|ERF3A_HUMAN,tr|H3BR35|H3BR35_HUMAN,tr|H3BSV8|H3BSV8_HUMAN" 4 1242.6601 0.65 99895 12398 3 1242.658909 415.2273 Eukaryotic peptide chain release factor GTP-binding subunit ERF3B OS=Homo sapiens OX=9606 GN=GSPT2 PE=1 SV=2 6.92 2309.5 - 879303 - - - -0.923 - 2.506 0.376 - 230.4 1 2 0 -0.0011 11 0 0 0 2.24E+07 3.47E+07 - - - 5.3415 0.9997 221125_WJC_METTL3_EV_vs_WT_F07.12399.12399.3 0.0172 15/48 R.ENLVR[166.11]PGIDHLGR[166.11].R "sp|Q9UPN6|SCAF8_HUMAN,tr|A0A0A0MT33|A0A0A0MT33_HUMAN" 2 1494.817 0.96 99896 12399 3 1494.819596 499.2796 SR-related and CTD-associated factor 8 OS=Homo sapiens OX=9606 GN=SCAF8 PE=1 SV=1 6.85 2309.7 - 665163 - - - 1.7367 - 2.509 0.318 - 330.9 1 2 0 0.0026 13 0 0 0 4.92E+06 5.11E+06 - - - 4.5787 1 221125_WJC_METTL3_EV_vs_WT_F07.12402.12402.2 1.07E-07 14/36 K.LSPQGYASPVSQSPQTSSK.Q "sp|P43694|GATA4_HUMAN,tr|B3KUF4|B3KUF4_HUMAN,tr|A0A087WZ09|A0A087WZ09_HUMAN" 3 1947.9538 3.68 99899 12402 2 1947.956242 974.9842 Transcription factor GATA-4 OS=Homo sapiens OX=9606 GN=GATA4 PE=1 SV=2 8.59 2310 - 432442 - - - 1.2613 - 2.494 0.653 - 418.1 1 2 0 0.0025 19 0 0 0 4.63E+06 1.26E+06 - - - 6.1101 0.9999 221125_WJC_METTL3_EV_vs_WT_F07.12407.12407.3 1.59E-06 Dec-52 K.GFYDKDSSGWSSSK.D "sp|O00571|DDX3X_HUMAN,tr|A0A2R8YFR4|A0A2R8YFR4_HUMAN,tr|A0A2R8YCW1|A0A2R8YCW1_HUMAN,tr|A0A2R8YDH3|A0A2R8YDH3_HUMAN,tr|A0A2R8Y645|A0A2R8Y645_HUMAN,tr|A0A2R8YF78|A0A2R8YF78_HUMAN,tr|A0A2R8YCU0|A0A2R8YCU0_HUMAN,tr|A0A0D9SFB3|A0A0D9SFB3_HUMAN,tr|A0A2R8YFS5|A0A2R8YFS5_HUMAN,tr|A0A0D9SF53|A0A0D9SF53_HUMAN,tr|A0A2R8Y650|A0A2R8Y650_HUMAN,tr|A0A087WX09|A0A087WX09_HUMAN,tr|A0A2R8Y5G6|A0A2R8Y5G6_HUMAN,tr|A0A0D9SG12|A0A0D9SG12_HUMAN,tr|F6S8Q4|F6S8Q4_HUMAN,tr|A0A2U3TZJ9|A0A2U3TZJ9_HUMAN,tr|A0A2R8Y4A4|A0A2R8Y4A4_HUMAN,tr|A0A2R8YF89|A0A2R8YF89_HUMAN" 18 1549.6685 1.51 99902 12407 3 1549.667712 517.5634 ATP-dependent RNA helicase DDX3X OS=Homo sapiens OX=9606 GN=DDX3X PE=1 SV=3 5.96 2310.6 - 3.21E+06 - - - -0.5098 - 2.404 0.622 - 128.8 1 2 1 -0.0008 14 0 0 0 8.15E+07 5.40E+07 - - - 7.8055 1 221125_WJC_METTL3_EV_vs_WT_F07.12409.12409.2 3.49E-08 16/24 R.TNEK[136.11]VELQELNDR[166.11].F "sp|P08670|VIME_HUMAN,sp|P17661|DESM_HUMAN,tr|B0YJC4|B0YJC4_HUMAN,tr|A0A1B0GTT5|A0A1B0GTT5_HUMAN" 4 1604.8125 1.97 99904 12409 2 1604.810943 803.4135 Vimentin OS=Homo sapiens OX=9606 GN=VIM PE=1 SV=4 4.41 2310.8 - 972799 - - - -0.9602 - 3.204 0.602 - 1095.3 1 2 1 -0.0015 13 0 0 0 3.96E+08 2.01E+08 - - - 6.4754 1 221125_WJC_METTL3_EV_vs_WT_F07.12413.12413.2 7.46E-12 15/30 S.NTPNSGYTQSQFSAPR[166.11].D "sp|Q14444|CAPR1_HUMAN,tr|G3V153|G3V153_HUMAN" 2 1763.8102 1.26 99908 12413 2 1763.80642 882.9124 Caprin-1 OS=Homo sapiens OX=9606 GN=CAPRIN1 PE=1 SV=2 8.75 2311.3 - 399233 - - - -2.1692 - 3.191 0.72 - 890.5 1 1 0 -0.0038 16 0 0 0 1.73E+07 1.37E+07 - - - 7.2105 0.9997 221125_WJC_METTL3_EV_vs_WT_F07.12418.12418.3 0.102 Dec-52 K.ATIAGGGVIPHIHK.S "sp|P0C0S5|H2AZ_HUMAN,sp|Q71UI9|H2AV_HUMAN" 2 1369.783 1.33 99911 12418 3 1369.781394 457.6016 Histone H2A.Z OS=Homo sapiens OX=9606 GN=H2AZ1 PE=1 SV=2 8.81 2312 - 4.63E+06 - - - -1.1863 - 2.71 0.278 - 175.4 1 2 0 -0.0016 14 0 0 0 7.77E+08 5.86E+08 - - - 4.2884 0.9999 221125_WJC_METTL3_EV_vs_WT_F07.12421.12421.4 0.000295 15/72 R.KTEELEEESFPER.S "sp|Q9Y2W1|TR150_HUMAN,tr|A0A3B3ITZ9|A0A3B3ITZ9_HUMAN" 2 1621.7471 3.71 99914 12421 4 1621.744899 406.4441 Thyroid hormone receptor-associated protein 3 OS=Homo sapiens OX=9606 GN=THRAP3 PE=1 SV=2 4.21 2312.3 - 1.19E+06 - - - -1.3855 - 2.446 0.412 - 162.3 1 2 0 -0.0022 13 0 0 0 7.87E+07 2.12E+07 - - - 3.1431 0.9999 221125_WJC_METTL3_EV_vs_WT_F07.12422.12422.4 0.000244 20/96 K.SWAQLNGKPVGHEGGLR.G sp|Q5JSZ5|PRC2B_HUMAN 1 1804.9333 1.12 99915 12422 4 1804.933828 452.2406 Protein PRRC2B OS=Homo sapiens OX=9606 GN=PRRC2B PE=1 SV=2 8.49 2312.4 - 1.14E+06 - - - 0.3119 - 2.747 0.393 - 274.6 1 2 0 0.0006 17 0 0 0 4.72E+07 4.24E+07 - - - 2.9974 1 221125_WJC_METTL3_EV_vs_WT_F07.12423.12423.2 1.53E-10 17/32 K.TFDEC[160.03]VAEGGSDC[160.03]APEK[136.11].L sp|Q7LGA3|HS2ST_HUMAN 1 1878.7491 1.4 99916 12423 2 1878.747785 940.3818 Heparan sulfate 2-O-sulfotransferase 1 OS=Homo sapiens OX=9606 GN=HS2ST1 PE=1 SV=1 3.83 2312.6 - 1.08E+06 - - - -0.7234 - 3.478 0.786 - 887.9 1 2 0 -0.0014 17 0 0 0 5.05E+07 3.61E+07 - - - 7.9104 1 221125_WJC_METTL3_EV_vs_WT_F07.12425.12425.2 4.08E-11 20/34 K.FSGEEGEIEDDESGTENR.E sp|Q9Y2W1|TR150_HUMAN 1 1998.7927 8.66 99918 12425 2 1998.791433 1000.4036 Thyroid hormone receptor-associated protein 3 OS=Homo sapiens OX=9606 GN=THRAP3 PE=1 SV=2 3.67 2312.8 - 676266 - - - -0.6104 - 3.937 0.731 - 1242.1 1 2 0 -0.0012 18 0 0 0 1.16E+07 1.34E+06 - - - 7.809 0.9999 221125_WJC_METTL3_EV_vs_WT_F07.12428.12428.3 0.000101 17/56 R.QASALIDR[166.11]PAPHFER[166.11].T "sp|P11171|EPB41_HUMAN,tr|A0A2R8Y6D0|A0A2R8Y6D0_HUMAN,tr|A0A2R8YFR9|A0A2R8YFR9_HUMAN,tr|A0A2R8Y420|A0A2R8Y420_HUMAN,tr|A0A2R8YCW8|A0A2R8YCW8_HUMAN,tr|A0A2R8Y7N0|A0A2R8Y7N0_HUMAN,tr|A0A3B3ITP0|A0A3B3ITP0_HUMAN,tr|A0A3B3IU06|A0A3B3IU06_HUMAN,tr|A0A2R8Y5G2|A0A2R8Y5G2_HUMAN,tr|A0A1B0GWG0|A0A1B0GWG0_HUMAN,tr|A0A2U3TZH6|A0A2U3TZH6_HUMAN,tr|A0A3B3IUD6|A0A3B3IUD6_HUMAN,tr|A0A2R8Y7Y3|A0A2R8Y7Y3_HUMAN,tr|A0A2R8Y570|A0A2R8Y570_HUMAN,tr|A0A2R8Y6G5|A0A2R8Y6G5_HUMAN,tr|A0A2R8Y5Z6|A0A2R8Y5Z6_HUMAN,tr|A0A2R8YD30|A0A2R8YD30_HUMAN,tr|A0A2R8Y4N6|A0A2R8Y4N6_HUMAN" 18 1726.9018 1 99919 12428 3 1726.901406 576.6412 Protein 4.1 OS=Homo sapiens OX=9606 GN=EPB41 PE=1 SV=4 6.75 2313.2 - 1.97E+06 - - - -0.2235 - 2.771 0.408 - 545.2 1 2 0 -0.0004 15 0 0 0 1.65E+07 1.64E+07 - - - 5.7482 1 221125_WJC_METTL3_EV_vs_WT_F07.12431.12431.3 5.02E-08 13/52 K.GFYDK[136.11]DSSGWSSSK[136.11].D "sp|O00571|DDX3X_HUMAN,tr|A0A2R8YFR4|A0A2R8YFR4_HUMAN,tr|A0A2R8YCW1|A0A2R8YCW1_HUMAN,tr|A0A2R8YDH3|A0A2R8YDH3_HUMAN,tr|A0A2R8Y645|A0A2R8Y645_HUMAN,tr|A0A2R8YF78|A0A2R8YF78_HUMAN,tr|A0A2R8YCU0|A0A2R8YCU0_HUMAN,tr|A0A0D9SFB3|A0A0D9SFB3_HUMAN,tr|A0A2R8YFS5|A0A2R8YFS5_HUMAN,tr|A0A0D9SF53|A0A0D9SF53_HUMAN,tr|A0A2R8Y650|A0A2R8Y650_HUMAN,tr|A0A087WX09|A0A087WX09_HUMAN,tr|A0A2R8Y5G6|A0A2R8Y5G6_HUMAN,tr|A0A0D9SG12|A0A0D9SG12_HUMAN,tr|F6S8Q4|F6S8Q4_HUMAN,tr|A0A2U3TZJ9|A0A2U3TZJ9_HUMAN,tr|A0A2R8Y4A4|A0A2R8Y4A4_HUMAN,tr|A0A2R8YF89|A0A2R8YF89_HUMAN" 18 1565.6969 1.49 99922 12431 3 1565.696829 522.9062 ATP-dependent RNA helicase DDX3X OS=Homo sapiens OX=9606 GN=DDX3X PE=1 SV=3 5.96 2313.5 - 2.44E+06 - - - -0.0466 - 2.777 0.633 - 146.4 1 2 1 -0.0001 14 0 0 0 8.04E+07 5.40E+07 - - - 8.3116 1 221125_WJC_METTL3_EV_vs_WT_F07.12432.12432.3 1.43E-06 19/56 R.QASALIDRPAPHFER.T "sp|P11171|EPB41_HUMAN,tr|A0A2R8Y6D0|A0A2R8Y6D0_HUMAN,tr|A0A2R8YFR9|A0A2R8YFR9_HUMAN,tr|A0A2R8Y420|A0A2R8Y420_HUMAN,tr|A0A2R8YCW8|A0A2R8YCW8_HUMAN,tr|A0A2R8Y7N0|A0A2R8Y7N0_HUMAN,tr|A0A3B3ITP0|A0A3B3ITP0_HUMAN,tr|A0A3B3IU06|A0A3B3IU06_HUMAN,tr|A0A2R8Y5G2|A0A2R8Y5G2_HUMAN,tr|A0A1B0GWG0|A0A1B0GWG0_HUMAN,tr|A0A2U3TZH6|A0A2U3TZH6_HUMAN,tr|A0A3B3IUD6|A0A3B3IUD6_HUMAN,tr|A0A2R8Y7Y3|A0A2R8Y7Y3_HUMAN,tr|A0A2R8Y570|A0A2R8Y570_HUMAN,tr|A0A2R8Y6G5|A0A2R8Y6G5_HUMAN,tr|A0A2R8Y5Z6|A0A2R8Y5Z6_HUMAN,tr|A0A2R8YD30|A0A2R8YD30_HUMAN,tr|A0A2R8Y4N6|A0A2R8Y4N6_HUMAN" 18 1706.8853 1 99923 12432 3 1706.884296 569.969 Protein 4.1 OS=Homo sapiens OX=9606 GN=EPB41 PE=1 SV=4 6.75 2313.6 - 2.00E+06 - - - -0.5601 - 2.969 0.469 - 652.2 1 2 0 -0.001 15 0 0 0 1.65E+07 1.64E+07 - - - 6.6082 1 221125_WJC_METTL3_EV_vs_WT_F07.12434.12434.2 1.42E-12 17/32 K.TFDEC[160.03]VAEGGSDC[160.03]APEK.L sp|Q7LGA3|HS2ST_HUMAN 1 1870.7349 1.4 99925 12434 2 1870.732039 936.3747 Heparan sulfate 2-O-sulfotransferase 1 OS=Homo sapiens OX=9606 GN=HS2ST1 PE=1 SV=1 3.83 2313.8 - 1.56E+06 - - - -1.5529 - 3.597 0.708 - 786.2 1 2 0 -0.0029 17 0 0 0 5.05E+07 3.61E+07 - - - 7.4166 1 221125_WJC_METTL3_EV_vs_WT_F07.12435.12435.3 1.16E-09 16/68 K.VTDTQEAEC[160.03]AGPPVPDPK.N "sp|Q99614|TTC1_HUMAN,tr|A0A804HKC5|A0A804HKC5_HUMAN,tr|A0A804HL30|A0A804HL30_HUMAN,tr|A0A804HHT7|A0A804HHT7_HUMAN,tr|A0A804HKI4|A0A804HKI4_HUMAN" 5 1909.8728 0.96 99926 12435 3 1909.868982 637.6315 Tetratricopeptide repeat protein 1 OS=Homo sapiens OX=9606 GN=TTC1 PE=1 SV=1 3.92 2314 - 1.06E+06 - - - -1.9771 - 2.473 0.651 - 86.9 1 2 0 -0.0038 18 0 0 0 3.21E+07 3.33E+07 - - - 8.0516 0.9947 221125_WJC_METTL3_EV_vs_WT_F07.12438.12438.2 3.35E-07 26-Dec A.SSEAPPLINEDVKR.T "sp|P04843|RPN1_HUMAN,tr|F8WF32|F8WF32_HUMAN" 2 1553.8049 1.35 99929 12438 2 1553.804631 777.9097 Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit 1 OS=Homo sapiens OX=9606 GN=RPN1 PE=1 SV=1 4.68 2314.4 - 630792 - - - -0.1963 - 2.405 0.573 - 259.3 1 1 0 -0.0003 14 0 0 0 1.09E+07 8.07E+06 - - - 5.4752 1 221125_WJC_METTL3_EV_vs_WT_F07.12441.12441.4 5.31E-08 23/84 R.QASALIDRPAPHFER.T "sp|P11171|EPB41_HUMAN,tr|A0A2R8Y6D0|A0A2R8Y6D0_HUMAN,tr|A0A2R8YFR9|A0A2R8YFR9_HUMAN,tr|A0A2R8Y420|A0A2R8Y420_HUMAN,tr|A0A2R8YCW8|A0A2R8YCW8_HUMAN,tr|A0A2R8Y7N0|A0A2R8Y7N0_HUMAN,tr|A0A3B3ITP0|A0A3B3ITP0_HUMAN,tr|A0A3B3IU06|A0A3B3IU06_HUMAN,tr|A0A2R8Y5G2|A0A2R8Y5G2_HUMAN,tr|A0A1B0GWG0|A0A1B0GWG0_HUMAN,tr|A0A2U3TZH6|A0A2U3TZH6_HUMAN,tr|A0A3B3IUD6|A0A3B3IUD6_HUMAN,tr|A0A2R8Y7Y3|A0A2R8Y7Y3_HUMAN,tr|A0A2R8Y570|A0A2R8Y570_HUMAN,tr|A0A2R8Y6G5|A0A2R8Y6G5_HUMAN,tr|A0A2R8Y5Z6|A0A2R8Y5Z6_HUMAN,tr|A0A2R8YD30|A0A2R8YD30_HUMAN,tr|A0A2R8Y4N6|A0A2R8Y4N6_HUMAN" 18 1706.8853 0.96 99930 12441 4 1706.883689 427.7286 Protein 4.1 OS=Homo sapiens OX=9606 GN=EPB41 PE=1 SV=4 6.75 2314.7 - 3.54E+06 - - - -0.9157 - 3.722 0.516 - 614.5 1 2 0 -0.0016 15 0 0 0 3.25E+07 3.37E+07 - - - 4.1871 0.9994 221125_WJC_METTL3_EV_vs_WT_F07.12443.12443.3 0.000283 13/48 R.TNEKVELQELNDR[166.11].F "sp|P08670|VIME_HUMAN,sp|P17661|DESM_HUMAN,tr|B0YJC4|B0YJC4_HUMAN,tr|A0A1B0GTT5|A0A1B0GTT5_HUMAN" 4 1596.7983 - 99932 12443 3 1596.799726 533.2734 Vimentin OS=Homo sapiens OX=9606 GN=VIM PE=1 SV=4 4.41 2314.9 - 2.67E+06 - - - 0.9031 - 2.569 0.366 - 218.5 2 2 1 0.0014 13 0 0 0 - - - - - 5.039 0.9955 221125_WJC_METTL3_EV_vs_WT_F07.12444.12444.2 0.000288 18-Nov K.QK[136.11]VENLFNEK[136.11].C "sp|P78347|GTF2I_HUMAN,tr|A0A494C1K3|A0A494C1K3_HUMAN" 2 1263.6794 1.74 99933 12444 2 1263.677465 632.847 General transcription factor II-I OS=Homo sapiens OX=9606 GN=GTF2I PE=1 SV=2 6.14 2315 - 2.09E+06 - - - -1.532 - 1.994 0.381 - 396.2 1 2 1 -0.0019 10 0 0 0 5.48E+07 3.15E+07 - - - 3.7809 0.9998 221125_WJC_METTL3_EV_vs_WT_F07.12445.12445.2 0.00174 15/20 K.KDLSQLQENLK.L sp|Q8IX12|CCAR1_HUMAN 1 1314.7143 66.99 99934 12445 2 1314.711653 658.3644 Cell division cycle and apoptosis regulator protein 1 OS=Homo sapiens OX=9606 GN=CCAR1 PE=1 SV=2 6.07 2315.2 - 1.41E+06 - - - -2.0362 - 3.168 0.424 - 553.3 1 2 0 -0.0027 11 0 0 0 1.68E+07 2.51E+05 - - - 5.2912 0.9999 221125_WJC_METTL3_EV_vs_WT_F07.12447.12447.3 1.73E-08 14/64 K.TFDEC[160.03]VAEGGSDC[160.03]APEK[136.11].L sp|Q7LGA3|HS2ST_HUMAN 1 1878.7491 1.98 99936 12447 3 1878.742645 627.257 Heparan sulfate 2-O-sulfotransferase 1 OS=Homo sapiens OX=9606 GN=HS2ST1 PE=1 SV=1 3.83 2315.4 - 2.80E+06 - - - -3.4592 - 2.288 0.621 - 136.5 1 2 0 -0.0065 17 0 0 0 1.67E+07 8.42E+06 - - - 7.5527 0.9993 221125_WJC_METTL3_EV_vs_WT_F07.12451.12451.3 0.00199 Sep-40 K.KDLSQLQENLK.L sp|Q8IX12|CCAR1_HUMAN 1 1314.7143 4.7 99938 12451 3 1314.713411 439.2454 Cell division cycle and apoptosis regulator protein 1 OS=Homo sapiens OX=9606 GN=CCAR1 PE=1 SV=2 6.07 2315.9 - 3.72E+06 - - - -0.699 - 1.856 0.293 - 178.9 1 2 0 -0.0009 11 0 0 0 4.52E+07 9.63E+06 - - - 3.5632 0.9963 221125_WJC_METTL3_EV_vs_WT_F07.12453.12453.2 0.000131 18-Nov K.QKVENLFNEK.C "sp|P78347|GTF2I_HUMAN,tr|A0A494C1K3|A0A494C1K3_HUMAN" 2 1247.651 1.74 99940 12453 2 1247.649768 624.8328 General transcription factor II-I OS=Homo sapiens OX=9606 GN=GTF2I PE=1 SV=2 6.14 2316 - 3.10E+06 - - - -0.9883 - 2.065 0.351 - 442.5 1 2 1 -0.0012 10 0 0 0 5.48E+07 3.15E+07 - - - 3.6572 1 221125_WJC_METTL3_EV_vs_WT_F07.12458.12458.2 8.44E-09 15/26 K.DC[160.03]DLQEDAC[160.03]YNC[160.03]GR[166.11].G sp|P62633|CNBP_HUMAN 1 1784.6428 1.07 99943 12458 2 1784.641171 893.3287 CCHC-type zinc finger nucleic acid binding protein OS=Homo sapiens OX=9606 GN=CNBP PE=1 SV=1 3.84 2316.6 - 1.59E+06 - - - -0.9066 - 2.68 0.725 - 258 1 2 0 -0.0016 14 0 0 0 4.34E+07 4.06E+07 - - - 6.8692 1 221125_WJC_METTL3_EV_vs_WT_F07.12462.12462.3 4.91E-06 16/76 K.NQAAIQGR[166.11]PPYAASAEEVAK[136.11].E "sp|Q9NZB2|F120A_HUMAN,tr|A0A0C4DG79|A0A0C4DG79_HUMAN,tr|A0A494C0Y9|A0A494C0Y9_HUMAN" 3 2088.0719 1.36 99947 12462 3 2088.074158 697.0312 Constitutive coactivator of PPAR-gamma-like protein 1 OS=Homo sapiens OX=9606 GN=FAM120A PE=1 SV=2 6.14 2317.1 - 1.30E+06 - - - 1.0876 - 3.414 0.493 - 306.5 1 2 0 0.0023 20 0 0 0 6.60E+07 4.86E+07 - - - 7.0147 1 221125_WJC_METTL3_EV_vs_WT_F07.12464.12464.2 1.68E-08 14/30 S.NTPNSGYTQSQFSAPR.D "sp|Q14444|CAPR1_HUMAN,tr|G3V153|G3V153_HUMAN" 2 1753.802 1.3 99949 12464 2 1753.805575 877.9083 Caprin-1 OS=Homo sapiens OX=9606 GN=CAPRIN1 PE=1 SV=2 8.75 2317.4 - 785248 - - - 2.0521 - 2.776 0.645 - 524.8 1 1 0 0.0036 16 0 0 0 1.78E+07 1.37E+07 - - - 6.314 1 221125_WJC_METTL3_EV_vs_WT_F07.12469.12469.2 1.26E-13 15/26 K.DC[160.03]DLQEDAC[160.03]YNC[160.03]GR.G sp|P62633|CNBP_HUMAN 1 1774.6345 1.07 99952 12469 2 1774.633982 888.3245 CCHC-type zinc finger nucleic acid binding protein OS=Homo sapiens OX=9606 GN=CNBP PE=1 SV=1 3.84 2317.9 - 1.93E+06 - - - -0.3026 - 3.125 0.816 - 805.2 1 2 0 -0.0005 14 0 0 0 4.34E+07 4.06E+07 - - - 7.9272 0.9987 221125_WJC_METTL3_EV_vs_WT_F07.12472.12472.2 0.000341 14/26 K.ATIAGGGVIPHIHK.S "sp|P0C0S5|H2AZ_HUMAN,sp|Q71UI9|H2AV_HUMAN" 2 1369.783 1.23 99955 12472 2 1369.777538 685.8988 Histone H2A.Z OS=Homo sapiens OX=9606 GN=H2AZ1 PE=1 SV=2 8.81 2318.2 - 944706 - - - -4.0014 - 2.514 0.437 - 517.3 1 2 0 -0.0055 14 0 0 0 5.21E+07 4.25E+07 - - - 4.5804 1 221125_WJC_METTL3_EV_vs_WT_F07.12473.12473.3 0.000249 20/64 K.LHETVDATSETHIYQVR[166.11].L "sp|Q9P2I0|CPSF2_HUMAN,tr|H0YJF4|H0YJF4_HUMAN" 2 2007.9889 6.34 99956 12473 3 2007.991093 670.3369 Cleavage and polyadenylation specificity factor subunit 2 OS=Homo sapiens OX=9606 GN=CPSF2 PE=1 SV=2 5.27 2318.3 - 598398 - - - 1.0727 - 3.791 0.602 - 490.9 1 2 0 0.0022 17 0 0 0 6.17E+07 9.74E+06 - - - 8.6177 1 221125_WJC_METTL3_EV_vs_WT_F07.12477.12477.3 4.30E-07 18/76 K.NQAAIQGRPPYAASAEEVAK.E "sp|Q9NZB2|F120A_HUMAN,tr|A0A0C4DG79|A0A0C4DG79_HUMAN,tr|A0A494C0Y9|A0A494C0Y9_HUMAN" 3 2070.0494 1.37 99958 12477 3 2070.049865 691.0237 Constitutive coactivator of PPAR-gamma-like protein 1 OS=Homo sapiens OX=9606 GN=FAM120A PE=1 SV=2 6.14 2318.9 - 2.27E+06 - - - 0.2164 - 3.415 0.482 - 323 1 2 0 0.0004 20 0 0 0 6.65E+07 4.86E+07 - - - 6.8933 0.9829 221125_WJC_METTL3_EV_vs_WT_F07.12479.12479.2 0.00473 12-Aug E.EESFPER.S "sp|Q9Y2W1|TR150_HUMAN,tr|A0A3B3ITZ9|A0A3B3ITZ9_HUMAN" 2 892.3927 4.16 99960 12479 2 892.392333 447.2036 Thyroid hormone receptor-associated protein 3 OS=Homo sapiens OX=9606 GN=THRAP3 PE=1 SV=2 4.25 2319.1 - 1.31E+06 - - - -0.3676 - 1.565 0.429 - 283.1 1 1 0 -0.0003 7 0 0 0 2.27E+07 5.45E+06 - - - 3.6286 1 221125_WJC_METTL3_EV_vs_WT_F07.12480.12480.3 1.24E-08 15/52 K.DC[160.03]DLQEDAC[160.03]YNC[160.03]GR[166.11].G sp|P62633|CNBP_HUMAN 1 1784.6428 3.78 99961 12480 3 1784.643069 595.8882 CCHC-type zinc finger nucleic acid binding protein OS=Homo sapiens OX=9606 GN=CNBP PE=1 SV=1 3.84 2319.3 - 1.18E+06 - - - 0.1569 - 2.877 0.685 - 435.4 1 2 0 0.0003 14 0 0 0 5.53E+07 1.46E+07 - - - 8.9853 0.9999 221125_WJC_METTL3_EV_vs_WT_F07.12484.12484.3 2.32E-05 19/56 K.TREGVVQGVASVAEK.T sp|Q16143|SYUB_HUMAN 1 1528.8209 1.4 99963 12484 3 1528.819427 510.6142 Beta-synuclein OS=Homo sapiens OX=9606 GN=SNCB PE=1 SV=1 5.81 2319.8 - 1.89E+06 - - - -0.9766 - 2.99 0.484 - 560.4 1 2 1 -0.0015 15 0 0 0 3.45E+08 2.47E+08 - - - 6.7937 0.9999 221125_WJC_METTL3_EV_vs_WT_F07.12486.12486.3 1.27E-05 13/68 K.YPPQEAEQLSHQAAPGPR[166.11].R "sp|O94761|RECQ4_HUMAN,tr|A0A087X072|A0A087X072_HUMAN,tr|V9GZ64|V9GZ64_HUMAN" 3 1984.9631 0.37 99965 12486 3 1984.969278 662.6616 ATP-dependent DNA helicase Q4 OS=Homo sapiens OX=9606 GN=RECQL4 PE=1 SV=2 5.4 2320 - 1.15E+06 - - - 3.1336 - 2.422 0.5 - 181.6 1 2 0 0.0062 18 0 0 0 1.32E+07 3.61E+07 - - - 6.3155 0.9997 221125_WJC_METTL3_EV_vs_WT_F07.12492.12492.3 0.000355 20/56 K.TR[166.11]EGVVQGVASVAEK[136.11].T sp|Q16143|SYUB_HUMAN 1 1546.8434 1.4 99969 12492 3 1546.842727 516.6217 Beta-synuclein OS=Homo sapiens OX=9606 GN=SNCB PE=1 SV=1 5.81 2320.7 - 4.31E+06 - - - -0.4286 - 3.06 0.386 - 613.4 1 2 1 -0.0007 15 0 0 0 3.45E+08 2.47E+08 - - - 5.7617 0.9561 221125_WJC_METTL3_EV_vs_WT_F07.12496.12496.2 0.00574 18-Oct A.GGGVIPHIHK.S "sp|P0C0S5|H2AZ_HUMAN,sp|Q71UI9|H2AV_HUMAN" 2 1013.577 1.31 99973 12496 2 1013.575193 507.7958 Histone H2A.Z OS=Homo sapiens OX=9606 GN=H2AZ1 PE=1 SV=2 8.76 2321.1 - 1.08E+06 - - - -1.8311 - 1.844 0.34 - 322.3 1 1 0 -0.0019 10 0 0 0 3.60E+07 2.75E+07 - - - 3.2598 1 221125_WJC_METTL3_EV_vs_WT_F07.12504.12504.2 2.22E-07 21/30 K.LKGEATVSFDDPPSAK.A "sp|P35637|FUS_HUMAN,tr|H3BPE7|H3BPE7_HUMAN" 2 1660.8308 1.04 99979 12504 2 1660.827901 831.4227 RNA-binding protein FUS OS=Homo sapiens OX=9606 GN=FUS PE=1 SV=1 4.56 2322 - 2.17E+06 - - - -1.7551 - 3.283 0.615 - 883.7 1 2 1 -0.0029 16 0 0 0 2.33E+08 2.24E+08 - - - 6.5051 0.9997 221125_WJC_METTL3_EV_vs_WT_F07.12507.12507.3 0.00883 15/44 K.K[136.11]LNK[136.11]EELPVIPK[136.11].G sp|Q9H6F5|CCD86_HUMAN 1 1430.8923 15.44 99982 12507 3 1430.889211 477.9714 Coiled-coil domain-containing protein 86 OS=Homo sapiens OX=9606 GN=CCDC86 PE=1 SV=1 8.5 2322.4 - 1.02E+06 - - - -2.1595 - 2.834 0.464 - 299.4 1 2 1 -0.0031 12 0 0 0 9.55E+08 6.18E+07 - - - 6.5997 0.9959 221125_WJC_METTL3_EV_vs_WT_F07.12509.12509.2 0.0919 18/28 K.TR[166.11]EGVVQGVASVAEK[136.11].T sp|Q16143|SYUB_HUMAN 1 1546.8434 1.44 99984 12509 2 1546.840264 774.429 Beta-synuclein OS=Homo sapiens OX=9606 GN=SNCB PE=1 SV=1 5.81 2322.6 - 746341 - - - -2.0209 - 2.939 0.356 - 373.7 1 2 1 -0.0031 15 0 0 0 5.35E+07 3.70E+07 - - - 4.3199 0.9904 221125_WJC_METTL3_EV_vs_WT_F07.12512.12512.3 7.59E-05 15/60 K.LK[136.11]GEATVSFDDPPSAK[136.11].A "sp|P35637|FUS_HUMAN,tr|H3BPE7|H3BPE7_HUMAN" 2 1676.8592 0.98 99985 12512 3 1676.856017 559.9603 RNA-binding protein FUS OS=Homo sapiens OX=9606 GN=FUS PE=1 SV=1 4.56 2323 - 6.70E+07 - - - -1.9077 - 2.396 0.213 - 225 1 2 1 -0.0032 16 0 0 0 2.71E+09 2.78E+09 - - - 3.1559 0.9979 221125_WJC_METTL3_EV_vs_WT_F07.12513.12513.2 1.43E-07 20/30 K.LK[136.11]GEATVSFDDPPSAK[136.11].A "sp|P35637|FUS_HUMAN,tr|H3BPE7|H3BPE7_HUMAN" 2 1676.8592 1.03 99986 12513 2 1676.856626 839.4369 RNA-binding protein FUS OS=Homo sapiens OX=9606 GN=FUS PE=1 SV=1 4.56 2323.1 - 4.26E+06 - - - -1.5446 - 3.342 0.395 - 779.7 1 2 1 -0.0026 16 0 0 0 2.33E+08 2.26E+08 - - - 4.9241 0.9997 221125_WJC_METTL3_EV_vs_WT_F07.12517.12517.4 6.33E-05 18/72 K.NKFDVDAADEKFR.R sp|Q9H0D6|XRN2_HUMAN 1 1553.7474 0.94 99990 12517 4 1553.743288 389.4441 5'-3' exoribonuclease 2 OS=Homo sapiens OX=9606 GN=XRN2 PE=1 SV=1 4.68 2323.5 - 1.38E+06 - - - -2.66 - 3.315 0.484 - 399.3 1 2 2 -0.0041 13 0 0 0 1.69E+07 1.81E+07 - - - 3.8819 0.9999 221125_WJC_METTL3_EV_vs_WT_F07.12518.12518.4 4.77E-07 20/72 K.NK[136.11]FDVDAADEK[136.11]FR[166.11].R sp|Q9H0D6|XRN2_HUMAN 1 1579.7841 0.95 99991 12518 4 1579.783633 395.9533 5'-3' exoribonuclease 2 OS=Homo sapiens OX=9606 GN=XRN2 PE=1 SV=1 4.68 2323.6 - 845770 - - - -0.2899 - 3.505 0.497 - 683.4 1 2 2 -0.0005 13 0 0 0 1.69E+07 1.79E+07 - - - 4.0168 0.9999 221125_WJC_METTL3_EV_vs_WT_F07.12521.12521.3 1.20E-07 21/76 K.QSAQLTALAAQQQAAGK[136.11]EEK[136.11].S sp|Q96A49|SYAP1_HUMAN 1 2086.0989 2.28 99992 12521 3 2086.095114 696.3736 Synapse-associated protein 1 OS=Homo sapiens OX=9606 GN=SYAP1 PE=1 SV=1 6.14 2324 - 4.40E+06 - - - -1.8369 - 4.243 0.566 - 578.1 1 2 1 -0.0038 20 0 0 0 1.56E+08 6.83E+07 - - - 8.3555 0.9986 221125_WJC_METTL3_EV_vs_WT_F07.12523.12523.2 0.000103 18/28 K.TREGVVQGVASVAEK.T sp|Q16143|SYUB_HUMAN 1 1528.8209 1.44 99994 12523 2 1528.81876 765.4177 Beta-synuclein OS=Homo sapiens OX=9606 GN=SNCB PE=1 SV=1 5.81 2324.2 - 2.39E+06 - - - -1.4129 - 3.45 0.481 - 450.1 1 2 1 -0.0022 15 0 0 0 5.35E+07 3.70E+07 - - - 5.6376 0.9989 221125_WJC_METTL3_EV_vs_WT_F07.12524.12524.2 1.28E-07 28-Dec K.TGQPEELVSC[160.03]SDC[160.03]GR.S "sp|Q92785|REQU_HUMAN,tr|J3KMZ8|J3KMZ8_HUMAN" 2 1693.7036 1.12 99995 12524 2 1693.695978 847.8591 Zinc finger protein ubi-d4 OS=Homo sapiens OX=9606 GN=DPF2 PE=1 SV=2 4.14 2324.3 - 2.33E+06 - - - -4.4908 - 2.289 0.62 - 324.8 1 2 0 -0.0076 15 0 0 0 6.28E+07 5.63E+07 - - - 5.6539 1 221125_WJC_METTL3_EV_vs_WT_F07.12526.12526.3 6.09E-07 18/68 R.AVDLVEEESGAPGEEQR[166.11]R[166.11].W "sp|O60231|DHX16_HUMAN,tr|A0A140T947|A0A140T947_HUMAN,tr|A2AB15|A2AB15_HUMAN" 3 1989.9507 1.93 99997 12526 3 1989.949631 664.3242 Pre-mRNA-splicing factor ATP-dependent RNA helicase DHX16 OS=Homo sapiens OX=9606 GN=DHX16 PE=1 SV=2 4.14 2324.6 - 1.65E+06 - - - -0.5131 - 3.185 0.468 - 374.8 1 2 0 -0.001 18 0 0 0 4.71E+07 2.44E+07 - - - 6.6421 0.9998 221125_WJC_METTL3_EV_vs_WT_F07.12529.12529.3 1.08E-05 13/52 R.TKDTPLSLAC[160.03]SGGR.Q "sp|O75179|ANR17_HUMAN,sp|Q8IWZ3|ANKH1_HUMAN,tr|E9PDP5|E9PDP5_HUMAN,tr|H0YM23|H0YM23_HUMAN,tr|H3BLS9|H3BLS9_HUMAN,tr|H0YLQ3|H0YLQ3_HUMAN,tr|H7C2F5|H7C2F5_HUMAN" 7 1461.7246 1.35 99998 12529 3 1461.722357 488.2488 Ankyrin repeat domain-containing protein 17 OS=Homo sapiens OX=9606 GN=ANKRD17 PE=1 SV=3 7.89 2324.9 - 3.15E+06 - - - -1.5188 - 2.379 0.517 - 227.8 1 2 1 -0.0022 14 0 0 0 2.11E+08 1.56E+08 - - - 6.6067 1 221125_WJC_METTL3_EV_vs_WT_F07.12530.12530.3 1.79E-05 28/48 K.NKFDVDAADEKFR.R sp|Q9H0D6|XRN2_HUMAN 1 1553.7474 2.2 99999 12530 3 1553.743199 518.9231 5'-3' exoribonuclease 2 OS=Homo sapiens OX=9606 GN=XRN2 PE=1 SV=1 4.68 2325.1 - 2.93E+06 - - - -2.7173 - 4.282 0.606 - 1290.5 1 2 2 -0.0042 13 0 0 0 5.19E+07 2.36E+07 - - - 9.2385 0.9999 221125_WJC_METTL3_EV_vs_WT_F07.12532.12532.3 7.47E-07 22/48 K.NK[136.11]FDVDAADEK[136.11]FR[166.11].R sp|Q9H0D6|XRN2_HUMAN 1 1579.7841 2.17 100001 12532 3 1579.785461 527.602 5'-3' exoribonuclease 2 OS=Homo sapiens OX=9606 GN=XRN2 PE=1 SV=1 4.68 2325.2 - 2.21E+06 - - - 0.8672 - 3.651 0.547 - 809.6 1 2 2 0.0014 13 0 0 0 5.11E+07 2.36E+07 - - - 8.1493 0.9998 221125_WJC_METTL3_EV_vs_WT_F07.12535.12535.3 6.41E-08 17/52 K.LSVHDMK[136.11]PLDSPGR[166.11].R "sp|Q15643|TRIPB_HUMAN,tr|H0YJ97|H0YJ97_HUMAN" 2 1568.81 1.57 100004 12535 3 1568.803162 523.9439 Thyroid receptor-interacting protein 11 OS=Homo sapiens OX=9606 GN=TRIP11 PE=1 SV=3 6.75 2325.6 - 868582 - - - -4.3472 - 2.741 0.544 - 248 1 2 0 -0.0068 14 0 0 0 2.55E+07 1.63E+07 - - - 7.2828 0.999 221125_WJC_METTL3_EV_vs_WT_F07.12536.12536.3 0.157 13/44 K.QSLRPFC[160.03]TVC[160.03]NR.Y "sp|Q9ULV3|CIZ1_HUMAN,tr|Q5SYW2|Q5SYW2_HUMAN,tr|F5H2X7|F5H2X7_HUMAN,tr|H0Y5D5|H0Y5D5_HUMAN,tr|A0A0U1RQR2|A0A0U1RQR2_HUMAN,tr|A0A494C0L7|A0A494C0L7_HUMAN,tr|Q9BTG3|Q9BTG3_HUMAN" 7 1536.729 5.09 100005 12536 3 1536.725307 513.2503 Cip1-interacting zinc finger protein OS=Homo sapiens OX=9606 GN=CIZ1 PE=1 SV=2 9.02 2325.7 - 895435 - - - -2.3719 - 2.306 0.279 - 191.6 1 2 0 -0.0036 12 0 0 0 1.39E+08 2.74E+07 - - - 3.9655 0.9999 221125_WJC_METTL3_EV_vs_WT_F07.12539.12539.3 2.19E-07 19/52 R.TK[136.11]DTPLSLAC[160.03]SGGR[166.11].Q "sp|O75179|ANR17_HUMAN,sp|Q8IWZ3|ANKH1_HUMAN,tr|E9PDP5|E9PDP5_HUMAN,tr|H0YM23|H0YM23_HUMAN,tr|H3BLS9|H3BLS9_HUMAN,tr|H0YLQ3|H0YLQ3_HUMAN,tr|H7C2F5|H7C2F5_HUMAN" 7 1479.747 1.35 100006 12539 3 1479.748161 494.2563 Ankyrin repeat domain-containing protein 17 OS=Homo sapiens OX=9606 GN=ANKRD17 PE=1 SV=3 7.89 2326.1 - 3.15E+06 - - - 0.7528 - 2.772 0.512 - 569.5 1 2 1 0.0011 14 0 0 0 2.11E+08 1.56E+08 - - - 6.9575 0.9999 221125_WJC_METTL3_EV_vs_WT_F07.12541.12541.3 0.0537 16/68 R.AVDLVEEESGAPGEEQRR.W "sp|O60231|DHX16_HUMAN,tr|A0A140T947|A0A140T947_HUMAN,tr|A2AB15|A2AB15_HUMAN" 3 1969.9341 1.55 100008 12541 3 1969.929844 657.652 Pre-mRNA-splicing factor ATP-dependent RNA helicase DHX16 OS=Homo sapiens OX=9606 GN=DHX16 PE=1 SV=2 4.14 2326.3 - 3.56E+06 - - - -2.1666 - 2.98 0.481 - 335.8 1 2 0 -0.0043 18 0 0 0 4.75E+07 3.07E+07 - - - 6.6205 1 221125_WJC_METTL3_EV_vs_WT_F07.12543.12543.3 2.63E-05 16/48 R.KTEELEEESFPER[166.11].S "sp|Q9Y2W1|TR150_HUMAN,tr|A0A3B3ITZ9|A0A3B3ITZ9_HUMAN" 2 1631.7554 - 100010 12543 3 1631.756129 544.9257 Thyroid hormone receptor-associated protein 3 OS=Homo sapiens OX=9606 GN=THRAP3 PE=1 SV=2 4.21 2326.5 - 3.04E+06 - - - 0.437 - 3.148 0.433 - 353.3 2 2 0 0.0007 13 0 0 0 - - - - - 6.3372 1 221125_WJC_METTL3_EV_vs_WT_F07.12544.12544.2 2.56E-07 16/32 K.AASSQTPTMC[160.03]TTTVTVK.L sp|Q08554|DSC1_HUMAN 1 1782.8492 999 100011 12544 2 1782.849754 892.4319 Desmocollin-1 OS=Homo sapiens OX=9606 GN=DSC1 PE=1 SV=2 8.27 2326.7 - 1.52E+06 - - - 0.3186 - 2.647 0.611 - 209.7 1 2 0 0.0006 17 0 0 0 2.90E+07 0.00E+00 - - - 5.9469 0.9979 221125_WJC_METTL3_EV_vs_WT_F07.12548.12548.3 0.0112 Dec-56 K.QTLENER[166.11]GELANEVK[136.11].V sp|P35579|MYH9_HUMAN 1 1746.8867 0.99 100013 12548 3 1746.883968 583.3028 Myosin-9 OS=Homo sapiens OX=9606 GN=MYH9 PE=1 SV=4 4.49 2327.2 - 5.13E+06 - - - -1.5708 - 2.445 0.293 - 174.9 1 2 1 -0.0027 15 0 0 0 4.97E+08 5.00E+08 - - - 4.1388 0.9999 221125_WJC_METTL3_EV_vs_WT_F07.12560.12560.4 1.11E-05 15/78 K.VAVNDAHLLQYNHR.V sp|P17931|LEG3_HUMAN 1 1648.8434 2 100021 12560 4 1648.842927 413.2181 Galectin-3 OS=Homo sapiens OX=9606 GN=LGALS3 PE=1 SV=5 6.89 2328.7 - 1.18E+06 - - - -0.279 - 2.622 0.396 - 190 1 2 0 -0.0005 14 0 0 0 2.11E+07 1.05E+07 - - - 3.0235 0.9107 221125_WJC_METTL3_EV_vs_WT_F07.12567.12567.2 5.51E-07 18/28 A.PVPLDDSNRPASLTK.D "sp|Q9NYF8|BCLF1_HUMAN,tr|E9PKI6|E9PKI6_HUMAN,tr|A0A1W2PQ43|A0A1W2PQ43_HUMAN,tr|E9PK91|E9PK91_HUMAN,tr|E9PJA7|E9PJA7_HUMAN,tr|E9PK09|E9PK09_HUMAN,tr|E9PQN2|E9PQN2_HUMAN" 7 1608.8471 4.58 100025 12567 2 1608.840919 805.4308 Bcl-2-associated transcription factor 1 OS=Homo sapiens OX=9606 GN=BCLAF1 PE=1 SV=2 6.38 2329.5 - 4.90E+06 - - - -3.8636 - 2.325 0.408 - 404.7 1 1 0 -0.0062 15 0 0 0 1.80E+08 3.93E+07 - - - 4.1269 0.999 221125_WJC_METTL3_EV_vs_WT_F07.12571.12571.3 0.000355 Nov-56 K.QTLENERGELANEVK.V sp|P35579|MYH9_HUMAN 1 1728.8642 1 100027 12571 3 1728.863785 577.2954 Myosin-9 OS=Homo sapiens OX=9606 GN=MYH9 PE=1 SV=4 4.49 2329.9 - 1.12E+07 - - - -0.2643 - 2.186 0.348 - 156.8 1 2 1 -0.0005 15 0 0 0 4.97E+08 4.95E+08 - - - 4.4604 1 221125_WJC_METTL3_EV_vs_WT_F07.12573.12573.4 6.57E-09 17/78 K.LSVHDMKPLDSPGR.R "sp|Q15643|TRIPB_HUMAN,tr|H0YJ97|H0YJ97_HUMAN" 2 1550.7875 1.24 100029 12573 4 1550.785315 388.7042 Thyroid receptor-interacting protein 11 OS=Homo sapiens OX=9606 GN=TRIP11 PE=1 SV=3 6.75 2330.2 - 1.07E+06 - - - -1.4167 - 3.015 0.564 - 280.4 1 2 0 -0.0022 14 0 0 0 2.59E+07 2.08E+07 - - - 4.5361 0.9999 221125_WJC_METTL3_EV_vs_WT_F07.12576.12576.3 0.000385 Nov-52 K.STNPGISIGDVAK[136.11]K[136.11].L "sp|O15347|HMGB3_HUMAN,tr|E9PES6|E9PES6_HUMAN,tr|E7EQU1|E7EQU1_HUMAN,tr|E7ES08|E7ES08_HUMAN" 4 1401.7798 0.15 100030 12576 3 1401.781186 468.2672 High mobility group protein B3 OS=Homo sapiens OX=9606 GN=HMGB3 PE=1 SV=4 8.31 2330.5 - 2.58E+06 - - - 0.9574 - 2.401 0.423 - 155 1 2 0 0.0013 14 0 0 0 9.92E+06 6.52E+07 - - - 5.5834 1 221125_WJC_METTL3_EV_vs_WT_F07.12578.12578.3 2.64E-06 19/64 R.C[160.03]SAGLGALAQRPGSVSK.W "sp|Q9NXV2|KCTD5_HUMAN,tr|H3BSS5|H3BSS5_HUMAN" 2 1657.857 4.14 100032 12578 3 1657.854656 553.6263 BTB\POZ domain-containing protein KCTD5 OS=Homo sapiens OX=9606 GN=KCTD5 PE=1 SV=1 9.51 2330.7 - 6.87E+07 - - - -1.4072 - 3.803 0.611 - 646.7 1 2 0 -0.0023 17 0 0 0 8.63E+09 2.08E+09 - - - 8.726 0.9904 221125_WJC_METTL3_EV_vs_WT_F07.12581.12581.2 0.000674 28-Sep K.QTLENER[166.11]GELANEVK[136.11].V sp|P35579|MYH9_HUMAN 1 1746.8867 1 100035 12581 2 1746.882145 874.4506 Myosin-9 OS=Homo sapiens OX=9606 GN=MYH9 PE=1 SV=4 4.49 2330.9 - 902463 - - - -2.6144 - 2.256 0.369 - 99.4 1 2 1 -0.0046 15 0 0 0 2.52E+07 2.52E+07 - - - 3.7653 1 221125_WJC_METTL3_EV_vs_WT_F07.12585.12585.2 3.85E-11 24/32 R.C[160.03]SAGLGALAQRPGSVSK.W "sp|Q9NXV2|KCTD5_HUMAN,tr|H3BSS5|H3BSS5_HUMAN" 2 1657.857 5.51 100037 12585 2 1657.854235 829.9358 BTB\POZ domain-containing protein KCTD5 OS=Homo sapiens OX=9606 GN=KCTD5 PE=1 SV=1 9.51 2331.4 - 5.16E+06 - - - -1.6612 - 3.899 0.675 - 1521.3 1 2 0 -0.0028 17 0 0 0 4.85E+08 8.81E+07 - - - 7.3711 0.7701 221125_WJC_METTL3_EV_vs_WT_F07.12595.12595.2 0.131 30-Sep A.QDQEASEQFGSPVAER[166.11].G sp|Q86W50|MET16_HUMAN 1 1786.7997 0.001 100044 12595 2 1786.802617 894.4071 RNA N6-adenosine-methyltransferase METTL16 OS=Homo sapiens OX=9606 GN=METTL16 PE=1 SV=2 4 2332.5 - 1.33E+06 - - - 1.6096 - 1.344 0.242 - 77.7 1 1 0 0.0029 16 0 0 0 0.00E+00 5.63E+07 - - - 1.5544 1 221125_WJC_METTL3_EV_vs_WT_F07.12596.12596.3 1.33E-08 19/52 R.YESLTDPSKLDSGK.E "sp|Q58FF8|H90B2_HUMAN,sp|P08238|HS90B_HUMAN,sp|Q58FF7|H90B3_HUMAN,sp|P07900|HS90A_HUMAN,sp|Q14568|HS902_HUMAN,tr|G3V2J8|G3V2J8_HUMAN" 6 1538.7464 0.72 100045 12596 3 1538.745951 513.9227 Putative heat shock protein HSP 90-beta 2 OS=Homo sapiens OX=9606 GN=HSP90AB2P PE=1 SV=2 4.56 2332.7 - 1.05E+06 - - - -0.3035 - 3.327 0.596 - 348.3 1 2 1 -0.0005 14 0 0 0 2.14E+08 2.95E+08 - - - 8.3792 0.9861 221125_WJC_METTL3_EV_vs_WT_F07.12601.12601.2 2.62E-07 14/28 A.PVPLDDSNR[166.11]PASLTK[136.11].D "sp|Q9NYF8|BCLF1_HUMAN,tr|E9PKI6|E9PKI6_HUMAN,tr|A0A1W2PQ43|A0A1W2PQ43_HUMAN,tr|E9PK91|E9PK91_HUMAN,tr|E9PJA7|E9PJA7_HUMAN,tr|E9PK09|E9PK09_HUMAN,tr|E9PQN2|E9PQN2_HUMAN" 7 1626.8696 4.57 100046 12601 2 1626.866189 814.4421 Bcl-2-associated transcription factor 1 OS=Homo sapiens OX=9606 GN=BCLAF1 PE=1 SV=2 6.38 2333.4 - 831539 - - - -2.0997 - 2.255 0.563 - 323.5 1 1 0 -0.0034 15 0 0 0 1.79E+08 3.93E+07 - - - 5.1974 1 221125_WJC_METTL3_EV_vs_WT_F07.12605.12605.2 4.16E-11 14/32 R.C[160.03]SAGLGALAQR[166.11]PGSVSK[136.11].W "sp|Q9NXV2|KCTD5_HUMAN,tr|H3BSS5|H3BSS5_HUMAN" 2 1675.8795 5.51 100049 12605 2 1675.875165 838.947 BTB\POZ domain-containing protein KCTD5 OS=Homo sapiens OX=9606 GN=KCTD5 PE=1 SV=1 9.51 2333.7 - 2.79E+06 - - - -2.5622 - 3.097 0.652 - 519.7 1 2 0 -0.0043 17 0 0 0 4.85E+08 8.81E+07 - - - 6.6345 1 221125_WJC_METTL3_EV_vs_WT_F07.12609.12609.3 1.58E-07 22/60 R.IFREEQNGEDEDGGWR.L "sp|Q6Y7W6|GGYF2_HUMAN,tr|I1E4Y6|I1E4Y6_HUMAN,tr|A0A7I2V516|A0A7I2V516_HUMAN,tr|A0A7I2V3H0|A0A7I2V3H0_HUMAN,tr|C9JHW1|C9JHW1_HUMAN,tr|E7ESB6|E7ESB6_HUMAN" 6 1935.8347 2.66 100051 12609 3 1935.833253 646.2855 GRB10-interacting GYF protein 2 OS=Homo sapiens OX=9606 GN=GIGYF2 PE=1 SV=1 4.08 2334.2 - 1.73E+06 - - - -0.7645 - 2.847 0.634 - 276.6 1 2 1 -0.0015 16 0 0 0 9.74E+07 3.66E+07 - - - 8.2926 1 221125_WJC_METTL3_EV_vs_WT_F07.12616.12616.3 4.13E-11 18/60 R.IFR[166.11]EEQNGEDEDGGWR[166.11].L "sp|Q6Y7W6|GGYF2_HUMAN,tr|I1E4Y6|I1E4Y6_HUMAN,tr|A0A7I2V516|A0A7I2V516_HUMAN,tr|A0A7I2V3H0|A0A7I2V3H0_HUMAN,tr|C9JHW1|C9JHW1_HUMAN,tr|E7ESB6|E7ESB6_HUMAN" 6 1955.8513 2.66 100054 12616 3 1955.848342 652.9577 GRB10-interacting GYF protein 2 OS=Homo sapiens OX=9606 GN=GIGYF2 PE=1 SV=1 4.08 2335 - 1.09E+06 - - - -1.4986 - 3.475 0.655 - 492.8 1 2 1 -0.0029 16 0 0 0 9.73E+07 3.66E+07 - - - 9.0378 0.9998 221125_WJC_METTL3_EV_vs_WT_F07.12621.12621.4 2.81E-06 17/78 R.QIILEKEETEELKR.F "sp|P12956|XRCC6_HUMAN,tr|B1AHC9|B1AHC9_HUMAN" 2 1756.9571 0.98 100056 12621 4 1756.960053 440.2465 X-ray repair cross-complementing protein 6 OS=Homo sapiens OX=9606 GN=XRCC6 PE=1 SV=2 4.65 2335.6 - 1.83E+06 - - - 1.6921 - 3.156 0.506 - 249.6 1 2 1 0.003 14 0 0 0 1.20E+08 1.21E+08 - - - 4.0477 1 221125_WJC_METTL3_EV_vs_WT_F07.12625.12625.2 4.36E-10 17/24 R.K[136.11]TEELEEESFPER[166.11].S "sp|Q9Y2W1|TR150_HUMAN,tr|A0A3B3ITZ9|A0A3B3ITZ9_HUMAN" 2 1639.7696 3.05 100058 12625 2 1639.767879 820.8921 Thyroid hormone receptor-associated protein 3 OS=Homo sapiens OX=9606 GN=THRAP3 PE=1 SV=2 4.21 2336.1 - 4.48E+06 - - - -1.0593 - 3.465 0.68 - 1049.8 1 2 0 -0.0017 13 0 0 0 2.05E+09 6.73E+08 - - - 7.2524 1 221125_WJC_METTL3_EV_vs_WT_F07.12627.12627.2 2.55E-10 17/26 G.RIEDVTPIPSDSTR.R "sp|P62263|RS14_HUMAN,tr|A0A2R8Y811|A0A2R8Y811_HUMAN" 2 1584.8108 0.06 100059 12627 2 1584.807973 793.4127 40S ribosomal protein S14 OS=Homo sapiens OX=9606 GN=RPS14 PE=1 SV=3 4.56 2336.3 - 1.38E+06 - - - -1.7523 - 3.227 0.618 - 406.5 1 1 0 -0.0028 14 0 0 0 6.20E+07 1.01E+09 - - - 6.5446 0.9999 221125_WJC_METTL3_EV_vs_WT_F07.12628.12628.3 1.01E-07 22/52 R.QIILEKEETEELKR.F "sp|P12956|XRCC6_HUMAN,tr|B1AHC9|B1AHC9_HUMAN" 2 1756.9571 1.13 100060 12628 3 1756.95626 586.6596 X-ray repair cross-complementing protein 6 OS=Homo sapiens OX=9606 GN=XRCC6 PE=1 SV=2 4.65 2336.4 - 1.27E+06 - - - -0.4667 - 3.976 0.471 - 953.4 1 2 1 -0.0008 14 0 0 0 9.46E+07 8.34E+07 - - - 7.4591 1 221125_WJC_METTL3_EV_vs_WT_F07.12632.12632.3 3.82E-10 16/44 R.TAAENEFVTLKK.D "sp|P48668|K2C6C_HUMAN,sp|P12035|K2C3_HUMAN,sp|P04259|K2C6B_HUMAN,sp|P02538|K2C6A_HUMAN" 4 1349.7191 279.41 100062 12632 3 1349.717681 450.9136 "Keratin, type II cytoskeletal 6C OS=Homo sapiens OX=9606 GN=KRT6C PE=1 SV=3" 5.81 2336.9 - 2.67E+06 - - - -1.0373 - 2.987 0.59 - 358.8 1 2 0 -0.0014 12 0 0 0 1.01E+08 3.63E+05 - - - 8.1507 0.9998 221125_WJC_METTL3_EV_vs_WT_F07.12633.12633.3 0.00288 20/52 R.QIILEK[136.11]EETEELK[136.11]R[166.11].F "sp|P12956|XRCC6_HUMAN,tr|B1AHC9|B1AHC9_HUMAN" 2 1782.9938 1.13 100063 12633 3 1782.989804 595.3385 X-ray repair cross-complementing protein 6 OS=Homo sapiens OX=9606 GN=XRCC6 PE=1 SV=2 4.65 2337 - 2.44E+06 - - - -2.2131 - 3.884 0.453 - 717.7 1 2 1 -0.0039 14 0 0 0 9.46E+07 8.34E+07 - - - 7.1953 0.9999 221125_WJC_METTL3_EV_vs_WT_F07.12634.12634.4 3.12E-08 22/78 R.QIILEK[136.11]EETEELK[136.11]R[166.11].F "sp|P12956|XRCC6_HUMAN,tr|B1AHC9|B1AHC9_HUMAN" 2 1782.9938 0.99 100064 12634 4 1782.991915 446.7557 X-ray repair cross-complementing protein 6 OS=Homo sapiens OX=9606 GN=XRCC6 PE=1 SV=2 4.65 2337 - 3.29E+06 - - - -1.0292 - 3.62 0.53 - 493.8 1 2 1 -0.0018 14 0 0 0 1.20E+08 1.21E+08 - - - 4.3068 1 221125_WJC_METTL3_EV_vs_WT_F07.12636.12636.3 3.40E-07 18/48 R.KTEELEEESFPER.S "sp|Q9Y2W1|TR150_HUMAN,tr|A0A3B3ITZ9|A0A3B3ITZ9_HUMAN" 2 1621.7471 3.04 100065 12636 3 1621.746943 541.5897 Thyroid hormone receptor-associated protein 3 OS=Homo sapiens OX=9606 GN=THRAP3 PE=1 SV=2 4.21 2337.2 - 1.30E+08 - - - -0.1252 - 3.285 0.532 - 541.4 1 2 0 -0.0002 13 0 0 0 1.58E+10 5.21E+09 - - - 7.6959 1 221125_WJC_METTL3_EV_vs_WT_F07.12643.12643.2 3.15E-06 13/26 R.QAVTNPNNTFYATK[136.11].R "sp|P38646|GRP75_HUMAN,tr|H0Y8K0|H0Y8K0_HUMAN,tr|A0A7I2V2S7|A0A7I2V2S7_HUMAN,tr|A0A7I2V2G2|A0A7I2V2G2_HUMAN,tr|A0A3B3ITI4|A0A3B3ITI4_HUMAN,tr|A0A7I2V3F7|A0A7I2V3F7_HUMAN,tr|A0A7I2YQB2|A0A7I2YQB2_HUMAN,tr|D6RCD7|D6RCD7_HUMAN" 8 1575.7773 0.18 100070 12643 2 1575.777738 788.8959 "Stress-70 protein, mitochondrial OS=Homo sapiens OX=9606 GN=HSPA9 PE=1 SV=2" 8.59 2338.2 - 499927 - - - 0.2964 - 2.718 0.59 - 573.2 1 2 0 0.0005 14 0 0 0 1.93E+06 1.05E+07 - - - 5.9078 1 221125_WJC_METTL3_EV_vs_WT_F07.12651.12651.2 1.33E-13 17/38 K.TSGLPANPSPGPAPQATSVK.L "sp|Q9P2N6|KANL3_HUMAN,tr|A0A590UJ53|A0A590UJ53_HUMAN" 2 1875.969 3.34 100075 12651 2 1875.971976 938.9918 KAT8 regulatory NSL complex subunit 3 OS=Homo sapiens OX=9606 GN=KANSL3 PE=1 SV=2 8.41 2339.1 - 649939 - - - 1.5645 - 3.029 0.717 - 506.6 1 2 0 0.0029 20 0 0 0 1.97E+07 5.90E+06 - - - 7.0605 0.9957 221125_WJC_METTL3_EV_vs_WT_F07.12653.12653.2 1.70E-05 13/26 R.YESLTDPSK[136.11]LDSGK[136.11].E "sp|Q58FF8|H90B2_HUMAN,sp|P08238|HS90B_HUMAN,sp|Q58FF7|H90B3_HUMAN,sp|P07900|HS90A_HUMAN,sp|Q14568|HS902_HUMAN,tr|G3V2J8|G3V2J8_HUMAN" 6 1554.7748 0.7 100077 12653 2 1554.770451 778.3947 Putative heat shock protein HSP 90-beta 2 OS=Homo sapiens OX=9606 GN=HSP90AB2P PE=1 SV=2 4.56 2339.4 - 631449 - - - -2.8088 - 2.413 0.539 - 535.7 1 2 1 -0.0044 14 0 0 0 1.25E+07 1.79E+07 - - - 5.2312 1 221125_WJC_METTL3_EV_vs_WT_F07.12656.12656.2 1.73E-14 17/30 K.TGSGDIENYNDATQVR.D "sp|P0DTE8|AMY1C_HUMAN,sp|P0DTE7|AMY1B_HUMAN,sp|P04746|AMYP_HUMAN,sp|P0DUB6|AMY1A_HUMAN,sp|P19961|AMY2B_HUMAN,tr|A0A804HHZ3|A0A804HHZ3_HUMAN" 6 1738.7758 307.85 100078 12656 2 1738.774282 870.3952 Alpha-amylase 1C OS=Homo sapiens OX=9606 GN=AMY1C PE=1 SV=1 4.03 2339.8 - 1.22E+06 - - - -0.8851 - 3.502 0.738 - 1050.7 1 2 0 -0.0015 16 0 0 0 4.54E+07 1.47E+05 - - - 7.5728 0.9971 221125_WJC_METTL3_EV_vs_WT_F07.12662.12662.3 1.77E-05 14/52 G.R[166.11]IEDVTPIPSDSTR[166.11].R "sp|P62263|RS14_HUMAN,tr|A0A2R8Y811|A0A2R8Y811_HUMAN" 2 1604.8273 1.25 100082 12662 3 1604.827632 535.9497 40S ribosomal protein S14 OS=Homo sapiens OX=9606 GN=RPS14 PE=1 SV=3 4.56 2340.5 - 1.20E+07 - - - 0.2131 - 2.767 0.483 - 315.7 1 1 0 0.0003 14 0 0 0 4.52E+08 3.63E+08 - - - 6.6296 0.9747 221125_WJC_METTL3_EV_vs_WT_F07.12665.12665.3 3.23E-06 15/52 R.GSDIK[136.11]DLTVC[160.03]EPPK[136.11].P "sp|Q8ND56|LS14A_HUMAN,sp|Q9BX40|LS14B_HUMAN,tr|I3L4Q1|I3L4Q1_HUMAN,tr|Q5TBQ1|Q5TBQ1_HUMAN,tr|A0A140TA76|A0A140TA76_HUMAN,tr|K7EMZ9|K7EMZ9_HUMAN,tr|A0A0C4DFV2|A0A0C4DFV2_HUMAN,tr|Q5TBQ0|Q5TBQ0_HUMAN" 8 1573.7993 1.76 100085 12665 3 1573.798262 525.607 Protein LSM14 homolog A OS=Homo sapiens OX=9606 GN=LSM14A PE=1 SV=3 4.56 2340.9 - 753585 - - - -0.6335 - 2.677 0.419 - 257 1 1 1 -0.001 14 0 0 0 7.18E+07 4.08E+07 - - - 5.828 0.997 221125_WJC_METTL3_EV_vs_WT_F07.12667.12667.2 4.25E-10 26-Dec R.YESLTDPSKLDSGK.E "sp|Q58FF8|H90B2_HUMAN,sp|P08238|HS90B_HUMAN,sp|Q58FF7|H90B3_HUMAN,sp|P07900|HS90A_HUMAN,sp|Q14568|HS902_HUMAN,tr|G3V2J8|G3V2J8_HUMAN" 6 1538.7464 0.7 100087 12667 2 1538.742472 770.3805 Putative heat shock protein HSP 90-beta 2 OS=Homo sapiens OX=9606 GN=HSP90AB2P PE=1 SV=2 4.56 2341.1 - 498648 - - - -2.5644 - 2.439 0.598 - 409.2 1 2 1 -0.0039 14 0 0 0 1.26E+07 1.79E+07 - - - 5.694 1 221125_WJC_METTL3_EV_vs_WT_F07.12673.12673.2 8.92E-11 13/34 M.ASGGGVPTDEEQATGLER.E sp|P10606|COX5B_HUMAN 1 1772.8177 1.43 100091 12673 2 1772.812635 887.4161 "Cytochrome c oxidase subunit 5B, mitochondrial OS=Homo sapiens OX=9606 GN=COX5B PE=1 SV=2" 4 2341.8 - 738639 - - - -2.8491 - 2.701 0.689 - 268.2 1 1 0 -0.005 18 0 0 0 2.08E+07 1.46E+07 - - - 6.5712 0.9998 221125_WJC_METTL3_EV_vs_WT_F07.12676.12676.4 0.00373 Dec-72 R.QADVFPDRDHFGR.T "sp|Q9HCC0|MCCB_HUMAN,tr|A0A804HJW5|A0A804HJW5_HUMAN,tr|A0A0G2JM88|A0A0G2JM88_HUMAN,tr|A0A804HK37|A0A804HK37_HUMAN,tr|A0A804HIH3|A0A804HIH3_HUMAN,tr|A0A804HJ24|A0A804HJ24_HUMAN,tr|A0A804HL02|A0A804HL02_HUMAN,tr|A0A804HKE8|A0A804HKE8_HUMAN,tr|D6RDF7|D6RDF7_HUMAN,tr|A0A804HJ84|A0A804HJ84_HUMAN,tr|A0A804HJW2|A0A804HJW2_HUMAN,tr|A0A804HLJ9|A0A804HLJ9_HUMAN,tr|D6R9R1|D6R9R1_HUMAN,tr|A0A804HHS4|A0A804HHS4_HUMAN,tr|A0A0S2Z5R4|A0A0S2Z5R4_HUMAN,tr|A0A804HJ31|A0A804HJ31_HUMAN" 16 1558.7277 1.01 100094 12676 4 1558.726309 390.6892 "Methylcrotonoyl-CoA carboxylase beta chain, mitochondrial OS=Homo sapiens OX=9606 GN=MCCC2 PE=1 SV=1" 5.3 2342.2 - 437610 - - - -0.8853 - 1.789 0.474 - 88.7 1 2 1 -0.0014 13 0 0 0 1.87E+07 1.85E+07 - - - 3.567 0.9997 221125_WJC_METTL3_EV_vs_WT_F07.12682.12682.3 4.47E-07 Sep-52 K.IEDDNDNAPYFEHR.V sp|Q08554|DSC1_HUMAN 1 1733.7281 999 100098 12682 3 1733.731236 578.9167 Desmocollin-1 OS=Homo sapiens OX=9606 GN=DSC1 PE=1 SV=2 4.1 2342.9 - 2.10E+06 - - - 1.7846 - 1.876 0.395 - 96.4 1 2 0 0.0031 14 0 0 0 1.25E+08 0.00E+00 - - - 4.615 0.999 221125_WJC_METTL3_EV_vs_WT_F07.12687.12687.4 0.0051 Dec-72 R.QADVFPDR[166.11]DHFGR[166.11].T "sp|Q9HCC0|MCCB_HUMAN,tr|A0A804HJW5|A0A804HJW5_HUMAN,tr|A0A0G2JM88|A0A0G2JM88_HUMAN,tr|A0A804HK37|A0A804HK37_HUMAN,tr|A0A804HIH3|A0A804HIH3_HUMAN,tr|A0A804HJ24|A0A804HJ24_HUMAN,tr|A0A804HL02|A0A804HL02_HUMAN,tr|A0A804HKE8|A0A804HKE8_HUMAN,tr|D6RDF7|D6RDF7_HUMAN,tr|A0A804HJ84|A0A804HJ84_HUMAN,tr|A0A804HJW2|A0A804HJW2_HUMAN,tr|A0A804HLJ9|A0A804HLJ9_HUMAN,tr|D6R9R1|D6R9R1_HUMAN,tr|A0A804HHS4|A0A804HHS4_HUMAN,tr|A0A0S2Z5R4|A0A0S2Z5R4_HUMAN,tr|A0A804HJ31|A0A804HJ31_HUMAN" 16 1578.7442 1.01 100103 12687 4 1578.743057 395.6933 "Methylcrotonoyl-CoA carboxylase beta chain, mitochondrial OS=Homo sapiens OX=9606 GN=MCCC2 PE=1 SV=1" 5.3 2343.5 - 661177 - - - -0.7424 - 2.117 0.367 - 97.5 1 2 1 -0.0012 13 0 0 0 1.87E+07 1.85E+07 - - - 2.6981 0.9999 221125_WJC_METTL3_EV_vs_WT_F07.12689.12689.2 1.12E-07 28-Oct K.TGQPEELVSC[160.03]SDC[160.03]GR[166.11].S "sp|Q92785|REQU_HUMAN,tr|J3KMZ8|J3KMZ8_HUMAN" 2 1703.7119 1.89 100105 12689 2 1703.713469 852.8632 Zinc finger protein ubi-d4 OS=Homo sapiens OX=9606 GN=DPF2 PE=1 SV=2 4.14 2343.7 - 242012 - - - 0.9479 - 2.191 0.562 - 294.1 1 2 0 0.0016 15 0 0 0 5.36E+07 2.83E+07 - - - 5.1198 1 221125_WJC_METTL3_EV_vs_WT_F07.12692.12692.3 5.31E-07 Nov-44 R.R[166.11]FDDAVVQSDMK[136.11].H "sp|P11142|HSP7C_HUMAN,tr|E9PQQ4|E9PQQ4_HUMAN,tr|E9PNE6|E9PNE6_HUMAN,tr|E9PKE3|E9PKE3_HUMAN,tr|E9PN89|E9PN89_HUMAN,tr|E9PLF4|E9PLF4_HUMAN,tr|E9PK54|E9PK54_HUMAN,tr|E9PN25|E9PN25_HUMAN,tr|E9PPY6|E9PPY6_HUMAN,tr|E9PQK7|E9PQK7_HUMAN" 10 1427.6834 0.1 100106 12692 3 1427.683715 476.9017 Heat shock cognate 71 kDa protein OS=Homo sapiens OX=9606 GN=HSPA8 PE=1 SV=1 4.43 2344.1 - 3.63E+06 - - - 0.2318 - 2.535 0.511 - 233.7 1 2 0 0.0003 12 0 0 0 4.57E+06 4.69E+07 - - - 6.8154 1 221125_WJC_METTL3_EV_vs_WT_F07.12696.12696.3 0.000255 14/32 K.HHPDLIFC[160.03]R.K sp|Q7RTV0|PHF5A_HUMAN 1 1193.5764 0.9 100110 12696 3 1193.577436 398.8661 PHD finger-like domain-containing protein 5A OS=Homo sapiens OX=9606 GN=PHF5A PE=1 SV=1 6.91 2344.4 - 1.06E+06 - - - 0.8705 - 2.314 0.477 - 340.2 1 2 0 0.001 9 0 0 0 1.64E+07 1.83E+07 - - - 6.3863 0.9997 221125_WJC_METTL3_EV_vs_WT_F07.12699.12699.3 0.0015 Sep-52 R.TK[136.11]PFC[160.03]C[160.03]SAC[160.03]PFSSK[136.11].F "sp|Q9H2P0|ADNP_HUMAN,tr|A0A669KBJ7|A0A669KBJ7_HUMAN" 2 1691.7441 0.22 100113 12699 3 1691.747512 564.922 Activity-dependent neuroprotector homeobox protein OS=Homo sapiens OX=9606 GN=ADNP PE=1 SV=1 8.65 2344.7 - 733071 - - - 2.0346 - 1.875 0.421 - 80.4 1 2 0 0.0034 14 0 0 0 3.40E+06 1.54E+07 - - - 4.9033 0.9927 221125_WJC_METTL3_EV_vs_WT_F07.12700.12700.4 0.196 Oct-72 R.KTEELEEESFPER.S "sp|Q9Y2W1|TR150_HUMAN,tr|A0A3B3ITZ9|A0A3B3ITZ9_HUMAN" 2 1621.7471 3.53 100114 12700 4 1621.74833 406.4441 Thyroid hormone receptor-associated protein 3 OS=Homo sapiens OX=9606 GN=THRAP3 PE=1 SV=2 4.21 2344.9 - 239126 - - - 0.7301 - 1.565 0.217 - 63.9 1 2 0 0.0012 13 0 0 0 8.20E+07 2.33E+07 - - - 1.2805 0.9999 221125_WJC_METTL3_EV_vs_WT_F07.12706.12706.3 0.000785 Dec-32 K.HHPDLIFC[160.03]R[166.11].K sp|Q7RTV0|PHF5A_HUMAN 1 1203.5847 0.95 100118 12706 3 1203.584116 402.2022 PHD finger-like domain-containing protein 5A OS=Homo sapiens OX=9606 GN=PHF5A PE=1 SV=1 6.91 2345.5 - 1.17E+06 - - - -0.4578 - 2.056 0.446 - 226.3 1 2 0 -0.0006 9 0 0 0 1.64E+07 1.73E+07 - - - 5.6845 1 221125_WJC_METTL3_EV_vs_WT_F07.12709.12709.3 9.52E-08 19/64 K.TQLQENETHSQLTNLER.K sp|Q96LB3|IFT74_HUMAN 1 2039.9872 3.29 100121 12709 3 2039.988052 681.003 Intraflagellar transport protein 74 homolog OS=Homo sapiens OX=9606 GN=IFT74 PE=1 SV=1 4.75 2345.8 - 753075 - - - 0.4123 - 3.518 0.542 - 460.3 1 2 0 0.0008 17 0 0 0 8.56E+06 2.60E+06 - - - 7.7603 1 221125_WJC_METTL3_EV_vs_WT_F07.12710.12710.3 8.67E-08 23/72 K.VNPFRPGDSEPPPAPGAQR.A "sp|Q15942|ZYX_HUMAN,tr|H0Y2Y8|H0Y2Y8_HUMAN,tr|C9IZ41|C9IZ41_HUMAN" 3 1987.9864 3.77 100122 12710 3 1987.988077 663.6694 Zyxin OS=Homo sapiens OX=9606 GN=ZYX PE=1 SV=1 6.04 2346 - 649031 - - - 0.832 - 3.614 0.556 - 562.2 1 2 0 0.0017 19 0 0 0 2.59E+08 6.86E+07 - - - 7.8949 0.9999 221125_WJC_METTL3_EV_vs_WT_F07.12711.12711.4 1.92E-05 Dec-84 K.KVNPDLQVEVKPSIR.A sp|Q96KR1|ZFR_HUMAN 1 1720.9836 1.18 100123 12711 4 1720.986983 431.2532 Zinc finger RNA-binding protein OS=Homo sapiens OX=9606 GN=ZFR PE=1 SV=2 8.59 2346.1 - 374935 - - - 1.9837 - 2.64 0.452 - 106.4 1 2 0 0.0034 15 0 0 0 6.97E+06 5.91E+06 - - - 3.5066 0.9999 221125_WJC_METTL3_EV_vs_WT_F07.12712.12712.4 0.00939 13/84 K.K[136.11]VNPDLQVEVK[136.11]PSIR[166.11].A sp|Q96KR1|ZFR_HUMAN 1 1747.0202 1.18 100124 12712 4 1747.022564 437.7623 Zinc finger RNA-binding protein OS=Homo sapiens OX=9606 GN=ZFR PE=1 SV=2 8.59 2346.2 - 227266 - - - 1.3308 - 2.482 0.437 - 151.9 1 2 0 0.0023 15 0 0 0 6.97E+06 5.91E+06 - - - 3.3543 0.9999 221125_WJC_METTL3_EV_vs_WT_F07.12713.12713.2 2.20E-06 Oct-32 K.TTPTPSTNSVLSTSTNR.S "sp|Q7KZI7|MARK2_HUMAN,tr|A0A0A0MRU9|A0A0A0MRU9_HUMAN,tr|E7ETY4|E7ETY4_HUMAN,tr|A0A7I2YQR3|A0A7I2YQR3_HUMAN,tr|E9PC69|E9PC69_HUMAN,tr|A0A7I2V3R3|A0A7I2V3R3_HUMAN" 6 1762.8697 9.38 100125 12713 2 1762.870161 882.4421 Serine\threonine-protein kinase MARK2 OS=Homo sapiens OX=9606 GN=MARK2 PE=1 SV=2 9.41 2346.4 - 224638 - - - 0.2496 - 1.977 0.554 - 147.4 1 2 0 0.0004 17 0 0 0 2.77E+06 2.96E+05 - - - 4.8084 0.9955 221125_WJC_METTL3_EV_vs_WT_F07.12718.12718.4 0.0164 14/84 K.NLSDSEKELYIQHAK.E sp|Q00059|TFAM_HUMAN 1 1773.8897 1.68 100128 12718 4 1773.89194 444.4797 "Transcription factor A, mitochondrial OS=Homo sapiens OX=9606 GN=TFAM PE=1 SV=1" 5.45 2346.9 - 2.12E+06 - - - 1.247 - 1.987 0.291 - 126.6 1 2 1 0.0022 15 0 0 0 3.29E+07 1.96E+07 - - - 2.0039 0.9992 221125_WJC_METTL3_EV_vs_WT_F07.12719.12719.4 0.000213 Dec-84 K.NLSDSEK[136.11]ELYIQHAK[136.11].E sp|Q00059|TFAM_HUMAN 1 1789.9181 1.68 100129 12719 4 1789.920591 448.4868 "Transcription factor A, mitochondrial OS=Homo sapiens OX=9606 GN=TFAM PE=1 SV=1" 5.45 2346.9 - 1.61E+06 - - - 1.376 - 2.199 0.386 - 77.4 1 2 1 0.0025 15 0 0 0 3.29E+07 1.96E+07 - - - 2.867 0.9999 221125_WJC_METTL3_EV_vs_WT_F07.12720.12720.3 6.09E-08 15/56 K.NLSDSEK[136.11]ELYIQHAK[136.11].E sp|Q00059|TFAM_HUMAN 1 1789.9181 1.17 100130 12720 3 1789.917876 597.6467 "Transcription factor A, mitochondrial OS=Homo sapiens OX=9606 GN=TFAM PE=1 SV=1" 5.45 2347 - 1.49E+06 - - - -0.1408 - 2.545 0.536 - 218.4 1 2 1 -0.0003 15 0 0 0 2.44E+07 2.08E+07 - - - 6.9533 0.9999 221125_WJC_METTL3_EV_vs_WT_F07.12722.12722.3 1.05E-07 19/60 K.IFVGGIK[136.11]EDTEEHHLR[166.11].D "sp|Q32P51|RA1L2_HUMAN,sp|P09651|ROA1_HUMAN,sp|P22626|ROA2_HUMAN,tr|A0A7I2YQN4|A0A7I2YQN4_HUMAN,tr|A0A7I2YQX9|A0A7I2YQX9_HUMAN,tr|A0A7I2V4N0|A0A7I2V4N0_HUMAN,tr|A0A024RA28|A0A024RA28_HUMAN,tr|A0A7I2V4N1|A0A7I2V4N1_HUMAN,tr|A0A7I2V4I6|A0A7I2V4I6_HUMAN,tr|F8VZ49|F8VZ49_HUMAN,tr|A0A7I2V3R8|A0A7I2V3R8_HUMAN,tr|A0A087WUI2|A0A087WUI2_HUMAN,tr|A0A7I2V4S4|A0A7I2V4S4_HUMAN,tr|F8VTQ5|F8VTQ5_HUMAN,tr|F8W6I7|F8W6I7_HUMAN,tr|A0A7I2V2L6|A0A7I2V2L6_HUMAN,tr|A0A7I2V323|A0A7I2V323_HUMAN,tr|A0A7I2V3W0|A0A7I2V3W0_HUMAN,tr|A0A7I2V5U9|A0A7I2V5U9_HUMAN,tr|A0A2R8Y4L2|A0A2R8Y4L2_HUMAN,tr|A0A7I2V3P1|A0A7I2V3P1_HUMAN,tr|A0A7I2V3P7|A0A7I2V3P7_HUMAN" 22 1896.9813 1.42 100132 12722 3 1896.983372 633.3344 Heterogeneous nuclear ribonucleoprotein A1-like 2 OS=Homo sapiens OX=9606 GN=HNRNPA1L2 PE=2 SV=2 5.36 2347.3 - 489484 - - - 1.1023 - 3.479 0.575 - 417.2 1 2 1 0.0021 16 0 0 0 3.86E+07 2.73E+07 - - - 8.1491 0.9999 221125_WJC_METTL3_EV_vs_WT_F07.12725.12725.3 1.16E-06 Nov-44 R.K[136.11]LFNLSK[136.11]EDDVR[166.11].Q "sp|P62753|RS6_HUMAN,tr|A2A3R5|A2A3R5_HUMAN" 2 1488.8147 0.91 100135 12725 3 1488.812603 497.2788 40S ribosomal protein S6 OS=Homo sapiens OX=9606 GN=RPS6 PE=1 SV=1 6.12 2347.6 - 352624 - - - -1.3837 - 2.633 0.559 - 197.1 1 2 1 -0.0021 12 0 0 0 5.81E+06 6.41E+06 - - - 7.4552 0.9999 221125_WJC_METTL3_EV_vs_WT_F07.12731.12731.3 2.43E-06 18/60 K.IFVGGIKEDTEEHHLR.D "sp|Q32P51|RA1L2_HUMAN,sp|P09651|ROA1_HUMAN,sp|P22626|ROA2_HUMAN,tr|A0A7I2YQN4|A0A7I2YQN4_HUMAN,tr|A0A7I2YQX9|A0A7I2YQX9_HUMAN,tr|A0A7I2V4N0|A0A7I2V4N0_HUMAN,tr|A0A024RA28|A0A024RA28_HUMAN,tr|A0A7I2V4N1|A0A7I2V4N1_HUMAN,tr|A0A7I2V4I6|A0A7I2V4I6_HUMAN,tr|F8VZ49|F8VZ49_HUMAN,tr|A0A7I2V3R8|A0A7I2V3R8_HUMAN,tr|A0A087WUI2|A0A087WUI2_HUMAN,tr|A0A7I2V4S4|A0A7I2V4S4_HUMAN,tr|F8VTQ5|F8VTQ5_HUMAN,tr|F8W6I7|F8W6I7_HUMAN,tr|A0A7I2V2L6|A0A7I2V2L6_HUMAN,tr|A0A7I2V323|A0A7I2V323_HUMAN,tr|A0A7I2V3W0|A0A7I2V3W0_HUMAN,tr|A0A7I2V5U9|A0A7I2V5U9_HUMAN,tr|A0A2R8Y4L2|A0A2R8Y4L2_HUMAN,tr|A0A7I2V3P1|A0A7I2V3P1_HUMAN,tr|A0A7I2V3P7|A0A7I2V3P7_HUMAN" 22 1878.9588 1.4 100139 12731 3 1878.961675 627.3269 Heterogeneous nuclear ribonucleoprotein A1-like 2 OS=Homo sapiens OX=9606 GN=HNRNPA1L2 PE=2 SV=2 5.36 2348.4 - 1.23E+06 - - - 1.5242 - 3.078 0.545 - 408.8 1 2 1 0.0029 16 0 0 0 3.81E+07 2.73E+07 - - - 7.5002 1 221125_WJC_METTL3_EV_vs_WT_F07.12732.12732.2 5.90E-08 16/24 R.KTEELEEESFPER.S "sp|Q9Y2W1|TR150_HUMAN,tr|A0A3B3ITZ9|A0A3B3ITZ9_HUMAN" 2 1621.7471 3.04 100140 12732 2 1621.749636 811.8808 Thyroid hormone receptor-associated protein 3 OS=Homo sapiens OX=9606 GN=THRAP3 PE=1 SV=2 4.21 2348.5 - 940769 - - - 1.5354 - 3.492 0.629 - 914.3 1 2 0 0.0025 13 0 0 0 2.23E+09 7.33E+08 - - - 6.8954 1 221125_WJC_METTL3_EV_vs_WT_F07.12733.12733.4 3.14E-10 23/90 K.IFVGGIK[136.11]EDTEEHHLR[166.11].D "sp|Q32P51|RA1L2_HUMAN,sp|P09651|ROA1_HUMAN,sp|P22626|ROA2_HUMAN,tr|A0A7I2YQN4|A0A7I2YQN4_HUMAN,tr|A0A7I2YQX9|A0A7I2YQX9_HUMAN,tr|A0A7I2V4N0|A0A7I2V4N0_HUMAN,tr|A0A024RA28|A0A024RA28_HUMAN,tr|A0A7I2V4N1|A0A7I2V4N1_HUMAN,tr|A0A7I2V4I6|A0A7I2V4I6_HUMAN,tr|F8VZ49|F8VZ49_HUMAN,tr|A0A7I2V3R8|A0A7I2V3R8_HUMAN,tr|A0A087WUI2|A0A087WUI2_HUMAN,tr|A0A7I2V4S4|A0A7I2V4S4_HUMAN,tr|F8VTQ5|F8VTQ5_HUMAN,tr|F8W6I7|F8W6I7_HUMAN,tr|A0A7I2V2L6|A0A7I2V2L6_HUMAN,tr|A0A7I2V323|A0A7I2V323_HUMAN,tr|A0A7I2V3W0|A0A7I2V3W0_HUMAN,tr|A0A7I2V5U9|A0A7I2V5U9_HUMAN,tr|A0A2R8Y4L2|A0A2R8Y4L2_HUMAN,tr|A0A7I2V3P1|A0A7I2V3P1_HUMAN,tr|A0A7I2V3P7|A0A7I2V3P7_HUMAN" 22 1896.9813 1.35 100141 12733 4 1896.984584 475.2526 Heterogeneous nuclear ribonucleoprotein A1-like 2 OS=Homo sapiens OX=9606 GN=HNRNPA1L2 PE=2 SV=2 5.36 2348.5 - 5.11E+06 - - - 1.7412 - 3.554 0.632 - 524.4 1 2 1 0.0033 16 0 0 0 1.46E+08 1.08E+08 - - - 5.1727 0.9999 221125_WJC_METTL3_EV_vs_WT_F07.12735.12735.3 8.39E-05 Dec-44 K.VQISQLHQEIQR.L sp|Q8N1N4|K2C78_HUMAN 1 1477.8001 4.45 100143 12735 3 1477.802324 493.6073 "Keratin, type II cytoskeletal 78 OS=Homo sapiens OX=9606 GN=KRT78 PE=1 SV=2" 6.72 2348.7 - 891965 - - - 1.488 - 2.77 0.416 - 294.4 1 2 0 0.0022 12 0 0 0 1.34E+07 3.01E+06 - - - 6.0015 1 221125_WJC_METTL3_EV_vs_WT_F07.12737.12737.3 2.39E-13 19/72 K.IHAVGAPSVC[160.03]SSC[160.03]GQSYYR.A sp|Q6DD87|ZN787_HUMAN 1 2097.936 0.35 100145 12737 3 2097.949855 700.3193 Zinc finger protein 787 OS=Homo sapiens OX=9606 GN=ZNF787 PE=1 SV=4 8.05 2348.9 - 854717 - - - 6.5831 - 3.797 0.685 - 416.5 1 2 0 0.0138 19 0 0 0 3.94E+06 1.13E+07 - - - 9.4511 0.9992 221125_WJC_METTL3_EV_vs_WT_F07.12740.12740.3 0.00278 13/36 R.NNR[166.11]YPNLQLR[166.11].E "sp|Q14671|PUM1_HUMAN,tr|Q5T1Z8|Q5T1Z8_HUMAN,tr|H0YDK8|H0YDK8_HUMAN,tr|H0YEH2|H0YEH2_HUMAN,tr|Q5T1Z4|Q5T1Z4_HUMAN,tr|E9PR38|E9PR38_HUMAN" 6 1306.7009 2.11 100148 12740 3 1306.703752 436.5742 Pumilio homolog 1 OS=Homo sapiens OX=9606 GN=PUM1 PE=1 SV=3 10.84 2349.3 - 540166 - - - 2.1772 - 2.319 0.396 - 384.6 1 2 1 0.0028 10 0 0 0 2.09E+07 9.91E+06 - - - 5.4107 0.9998 221125_WJC_METTL3_EV_vs_WT_F07.12745.12745.3 0.00201 14/28 R.R[166.11]DYLHYIR[166.11].K "sp|P62280|RS11_HUMAN,tr|M0R1H5|M0R1H5_HUMAN,tr|M0QZC5|M0QZC5_HUMAN" 3 1154.61 0.04 100151 12745 3 1154.610123 385.8773 40S ribosomal protein S11 OS=Homo sapiens OX=9606 GN=RPS11 PE=1 SV=3 8.6 2349.9 - 2.21E+06 - - - 0.1351 - 2.26 0.296 - 375.9 1 2 0 0.0002 8 0 0 0 1.24E+06 3.30E+07 - - - 4.3885 0.9999 221125_WJC_METTL3_EV_vs_WT_F07.12746.12746.3 0.000109 13/36 R.NNRYPNLQLR.E "sp|Q14671|PUM1_HUMAN,tr|Q5T1Z8|Q5T1Z8_HUMAN,tr|H0YDK8|H0YDK8_HUMAN,tr|H0YEH2|H0YEH2_HUMAN,tr|Q5T1Z4|Q5T1Z4_HUMAN,tr|E9PR38|E9PR38_HUMAN" 6 1286.6844 2.12 100152 12746 3 1286.684429 429.9021 Pumilio homolog 1 OS=Homo sapiens OX=9606 GN=PUM1 PE=1 SV=3 10.84 2350 - 1.27E+06 - - - 0.0482 - 2.781 0.5 - 414.3 1 2 1 0.0001 10 0 0 0 2.08E+07 9.83E+06 - - - 7.1015 1 221125_WJC_METTL3_EV_vs_WT_F07.12747.12747.3 3.30E-10 17/60 K.HLSPYATLTVGDSSHK.T sp|Q9BSJ8|ESYT1_HUMAN 1 1711.8529 1.32 100153 12747 3 1711.856238 571.6249 Extended synaptotagmin-1 OS=Homo sapiens OX=9606 GN=ESYT1 PE=1 SV=1 6.92 2350 - 1.25E+06 - - - 1.9213 - 3.432 0.589 - 518.2 1 2 0 0.0033 16 0 0 0 1.61E+07 1.22E+07 - - - 8.2699 1 221125_WJC_METTL3_EV_vs_WT_F07.12748.12748.3 0.00176 Dec-48 K.GEDFYC[160.03]VTC[160.03]HETK[136.11].F "sp|Q13642|FHL1_HUMAN,tr|Q5JXI2|Q5JXI2_HUMAN,tr|A0A0D9SFZ9|A0A0D9SFZ9_HUMAN,tr|A0A494C0D6|A0A494C0D6_HUMAN,tr|Q5JXH7|Q5JXH7_HUMAN,tr|Q5JXI8|Q5JXI8_HUMAN,tr|Q5JXH8|Q5JXH8_HUMAN,tr|Q5JXI3|Q5JXI3_HUMAN" 8 1652.669 0.73 100154 12748 3 1652.669463 551.897 Four and a half LIM domains protein 1 OS=Homo sapiens OX=9606 GN=FHL1 PE=1 SV=4 4.65 2350.1 - 1.18E+06 - - - 0.2541 - 2.38 0.551 - 192.5 1 2 0 0.0004 13 0 0 0 1.09E+07 1.49E+07 - - - 7.0339 1 221125_WJC_METTL3_EV_vs_WT_F07.12749.12749.3 0.000253 19/72 K.VNPFR[166.11]PGDSEPPPAPGAQR[166.11].A "sp|Q15942|ZYX_HUMAN,tr|H0Y2Y8|H0Y2Y8_HUMAN,tr|C9IZ41|C9IZ41_HUMAN" 3 2008.003 2.95 100155 12749 3 2008.00239 670.3416 Zyxin OS=Homo sapiens OX=9606 GN=ZYX PE=1 SV=1 6.04 2350.3 - 937215 - - - -0.2854 - 3.448 0.542 - 460.9 1 2 0 -0.0006 19 0 0 0 5.43E+07 1.84E+07 - - - 7.6236 0.8816 221125_WJC_METTL3_EV_vs_WT_F07.12750.12750.4 0.13 16/84 W.LDANTLAEKDEFEHK.R "sp|P0DMV8|HS71A_HUMAN,sp|P0DMV9|HS71B_HUMAN,tr|V9GZ37|V9GZ37_HUMAN,tr|A0A0G2JIW1|A0A0G2JIW1_HUMAN" 4 1758.8424 0.14 100156 12750 4 1758.842525 440.7179 Heat shock 70 kDa protein 1A OS=Homo sapiens OX=9606 GN=HSPA1A PE=1 SV=1 4.5 2350.4 - 822228 - - - 0.0461 - 2.736 0.35 - 230.9 1 1 1 0.0001 15 0 0 0 2.00E+07 1.43E+08 - - - 2.6325 1 221125_WJC_METTL3_EV_vs_WT_F07.12751.12751.3 2.61E-09 15/72 R.GVITDQNSDGYC[160.03]QTGTMSR.H "sp|P15924|DESP_HUMAN,tr|A0A804HL18|A0A804HL18_HUMAN" 2 2088.8841 0.15 100157 12751 3 2088.885814 697.302 Desmoplakin OS=Homo sapiens OX=9606 GN=DSP PE=1 SV=3 4.21 2350.5 - 780892 - - - 0.8359 - 3.335 0.589 - 263.3 1 2 0 0.0017 19 0 0 0 1.35E+07 9.21E+07 - - - 8.0654 0.9999 221125_WJC_METTL3_EV_vs_WT_F07.12758.12758.4 2.90E-10 19/90 K.IFVGGIKEDTEEHHLR.D "sp|Q32P51|RA1L2_HUMAN,sp|P09651|ROA1_HUMAN,sp|P22626|ROA2_HUMAN,tr|A0A7I2YQN4|A0A7I2YQN4_HUMAN,tr|A0A7I2YQX9|A0A7I2YQX9_HUMAN,tr|A0A7I2V4N0|A0A7I2V4N0_HUMAN,tr|A0A024RA28|A0A024RA28_HUMAN,tr|A0A7I2V4N1|A0A7I2V4N1_HUMAN,tr|A0A7I2V4I6|A0A7I2V4I6_HUMAN,tr|F8VZ49|F8VZ49_HUMAN,tr|A0A7I2V3R8|A0A7I2V3R8_HUMAN,tr|A0A087WUI2|A0A087WUI2_HUMAN,tr|A0A7I2V4S4|A0A7I2V4S4_HUMAN,tr|F8VTQ5|F8VTQ5_HUMAN,tr|F8W6I7|F8W6I7_HUMAN,tr|A0A7I2V2L6|A0A7I2V2L6_HUMAN,tr|A0A7I2V323|A0A7I2V323_HUMAN,tr|A0A7I2V3W0|A0A7I2V3W0_HUMAN,tr|A0A7I2V5U9|A0A7I2V5U9_HUMAN,tr|A0A2R8Y4L2|A0A2R8Y4L2_HUMAN,tr|A0A7I2V3P1|A0A7I2V3P1_HUMAN,tr|A0A7I2V3P7|A0A7I2V3P7_HUMAN" 22 1878.9588 1.35 100162 12758 4 1878.960882 470.747 Heterogeneous nuclear ribonucleoprotein A1-like 2 OS=Homo sapiens OX=9606 GN=HNRNPA1L2 PE=2 SV=2 5.36 2351.4 - 1.23E+07 - - - 1.1022 - 3.818 0.6 - 414.4 1 2 1 0.0021 16 0 0 0 1.48E+08 1.10E+08 - - - 4.9198 0.9866 221125_WJC_METTL3_EV_vs_WT_F07.12760.12760.3 0.00297 17/56 W.LDANTLAEKDEFEHK.R "sp|P0DMV8|HS71A_HUMAN,sp|P0DMV9|HS71B_HUMAN,tr|V9GZ37|V9GZ37_HUMAN,tr|A0A0G2JIW1|A0A0G2JIW1_HUMAN" 4 1758.8424 0.19 100164 12760 3 1758.845788 587.2881 Heat shock 70 kDa protein 1A OS=Homo sapiens OX=9606 GN=HSPA1A PE=1 SV=1 4.5 2351.6 - 1.32E+06 - - - 1.9013 - 3.545 0.504 - 476.7 1 1 1 0.0033 15 0 0 0 1.72E+07 9.22E+07 - - - 7.4604 1 221125_WJC_METTL3_EV_vs_WT_F07.12763.12763.3 3.05E-08 18/48 R.HVHADSTDFLAVK[136.11].R "sp|O94761|RECQ4_HUMAN,tr|A0A087X072|A0A087X072_HUMAN,tr|V9GZ64|V9GZ64_HUMAN" 3 1446.7347 0.66 100167 12763 3 1446.735398 483.2522 ATP-dependent DNA helicase Q4 OS=Homo sapiens OX=9606 GN=RECQL4 PE=1 SV=2 5.98 2351.9 - 773509 - - - 0.4977 - 3.404 0.439 - 386 1 2 0 0.0007 13 0 0 0 6.94E+06 1.05E+07 - - - 6.7554 1 221125_WJC_METTL3_EV_vs_WT_F07.12765.12765.3 1.46E-08 21/48 R.HVHADSTDFLAVK.R "sp|O94761|RECQ4_HUMAN,tr|A0A087X072|A0A087X072_HUMAN,tr|V9GZ64|V9GZ64_HUMAN" 3 1438.7205 0.26 100169 12765 3 1438.725208 480.5808 ATP-dependent DNA helicase Q4 OS=Homo sapiens OX=9606 GN=RECQL4 PE=1 SV=2 5.98 2352.1 - 554681 - - - 3.2876 - 3.285 0.62 - 678.7 1 2 0 0.0047 13 0 0 0 7.45E+06 2.83E+07 - - - 8.6758 0.9997 221125_WJC_METTL3_EV_vs_WT_F07.12773.12773.3 2.48E-05 17/60 K.HLSPYATLTVGDSSHK[136.11].T sp|Q9BSJ8|ESYT1_HUMAN 1 1719.8671 1.32 100175 12773 3 1719.869309 574.2963 Extended synaptotagmin-1 OS=Homo sapiens OX=9606 GN=ESYT1 PE=1 SV=1 6.92 2353.2 - 1.45E+06 - - - 1.2559 - 3.175 0.268 - 460.1 1 2 0 0.0022 16 0 0 0 1.61E+07 1.22E+07 - - - 4.4917 0.9999 221125_WJC_METTL3_EV_vs_WT_F07.12774.12774.3 0.00127 Dec-56 R.ELRPEDDMKPGSFDR.S sp|P22466|GALA_HUMAN 1 1790.8257 0.17 100176 12774 3 1790.829754 597.9492 Galanin peptides OS=Homo sapiens OX=9606 GN=GAL PE=1 SV=3 4.44 2353.3 - 1.23E+06 - - - 2.237 - 2.329 0.479 - 167.4 1 2 0 0.004 15 0 0 0 1.26E+07 7.58E+07 - - - 6.0853 0.9998 221125_WJC_METTL3_EV_vs_WT_F07.12775.12775.4 0.00247 Dec-84 R.ELRPEDDMKPGSFDR.S sp|P22466|GALA_HUMAN 1 1790.8257 0.25 100177 12775 4 1790.828196 448.7137 Galanin peptides OS=Homo sapiens OX=9606 GN=GAL PE=1 SV=3 4.44 2353.3 - 1.48E+06 - - - 1.367 - 2.311 0.379 - 86.2 1 2 0 0.0024 15 0 0 0 1.26E+07 4.98E+07 - - - 2.8239 0.9482 221125_WJC_METTL3_EV_vs_WT_F07.12777.12777.3 0.159 Oct-36 K.KKDYEVELLR.F "sp|P17480|UBF1_HUMAN,tr|E9PKP7|E9PKP7_HUMAN" 2 1291.7136 1.2 100179 12777 3 1291.717235 431.5785 Nucleolar transcription factor 1 OS=Homo sapiens OX=9606 GN=UBTF PE=1 SV=1 6.18 2353.5 - 1.30E+06 - - - 2.8125 - 1.925 0.18 - 190.1 1 2 1 0.0036 10 0 0 0 1.36E+07 1.13E+07 - - - 2.4585 0.9641 221125_WJC_METTL3_EV_vs_WT_F07.12778.12778.2 0.00139 14-Aug R.YPDGIISK[136.11].P sp|Q86U44|MTA70_HUMAN 1 899.4844 0.04 100180 12778 2 899.485116 450.7495 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 5.83 2353.6 - 1.09E+06 - - - 0.8149 - 1.527 0.364 - 161.6 1 1 0 0.0007 8 0 0 0 6.83E+05 1.91E+07 - - - 3.0059 1 221125_WJC_METTL3_EV_vs_WT_F07.12781.12781.2 1.21E-15 16/36 R.GVITDQNSDGYC[160.03]QTGTMSR.H "sp|P15924|DESP_HUMAN,tr|A0A804HL18|A0A804HL18_HUMAN" 2 2088.8841 2.17 100183 12781 2 2088.887399 1045.4493 Desmoplakin OS=Homo sapiens OX=9606 GN=DSP PE=1 SV=3 4.21 2354 - 550470 - - - 1.5946 - 3.786 0.632 - 808 1 2 0 0.0033 19 0 0 0 7.42E+06 3.41E+06 - - - 6.981 1 221125_WJC_METTL3_EV_vs_WT_F07.12786.12786.3 8.44E-08 21/64 K.QLLC[160.03]GAAIGTHEDDK[136.11]YR[166.11].L "sp|P12268|IMDH2_HUMAN,tr|A0A7I2YQK5|A0A7I2YQK5_HUMAN,tr|H0Y4R1|H0Y4R1_HUMAN,tr|A0A7I2V2T3|A0A7I2V2T3_HUMAN,tr|E7ETK5|E7ETK5_HUMAN" 5 1963.9541 1.07 100188 12786 3 1963.959849 655.6586 Inosine-5'-monophosphate dehydrogenase 2 OS=Homo sapiens OX=9606 GN=IMPDH2 PE=1 SV=2 5.38 2354.7 - 221629 - - - 2.9374 - 3.965 0.587 - 838 1 2 1 0.0058 17 0 0 0 1.91E+06 1.78E+06 - - - 8.5629 0.9992 221125_WJC_METTL3_EV_vs_WT_F07.12789.12789.2 0.000765 26-Jul K.QPC[160.03]QPPPQEPC[160.03]IPK.T "sp|P35321|SPR1A_HUMAN,sp|P22528|SPR1B_HUMAN" 2 1674.7858 72.48 100191 12789 2 1674.788024 838.4002 Cornifin-A OS=Homo sapiens OX=9606 GN=SPRR1A PE=1 SV=2 5.99 2355.1 - 170059 - - - 1.3291 - 1.492 0.402 - 160.8 1 2 0 0.0022 14 0 0 0 3.02E+07 4.17E+05 - - - 3.0135 0.9983 221125_WJC_METTL3_EV_vs_WT_F07.12792.12792.2 0.0121 30-Aug K.QGSDAYDAQTYDVASK[136.11].E sp|Q9NU22|MDN1_HUMAN 1 1725.7573 0.7 100193 12792 2 1725.755903 863.8859 Midasin OS=Homo sapiens OX=9606 GN=MDN1 PE=1 SV=2 3.93 2355.6 - 207790 - - - -0.8234 - 1.178 0.348 - 117.7 1 2 0 -0.0014 16 0 0 0 4.74E+06 6.79E+06 - - - 2.0136 0.9999 221125_WJC_METTL3_EV_vs_WT_F07.12797.12797.4 5.03E-10 19/96 K.QLLC[160.03]GAAIGTHEDDK[136.11]YR[166.11].L "sp|P12268|IMDH2_HUMAN,tr|A0A7I2YQK5|A0A7I2YQK5_HUMAN,tr|H0Y4R1|H0Y4R1_HUMAN,tr|A0A7I2V2T3|A0A7I2V2T3_HUMAN,tr|E7ETK5|E7ETK5_HUMAN" 5 1963.9541 0.64 100197 12797 4 1963.956034 491.9958 Inosine-5'-monophosphate dehydrogenase 2 OS=Homo sapiens OX=9606 GN=IMPDH2 PE=1 SV=2 5.38 2355.9 - 1.33E+06 - - - 0.9949 - 4.039 0.556 - 416.5 1 2 1 0.002 17 0 0 0 3.21E+06 4.98E+06 - - - 4.5496 0.9998 221125_WJC_METTL3_EV_vs_WT_F07.12800.12800.4 9.98E-06 18/96 K.QLLC[160.03]GAAIGTHEDDKYR.L "sp|P12268|IMDH2_HUMAN,tr|A0A7I2YQK5|A0A7I2YQK5_HUMAN,tr|H0Y4R1|H0Y4R1_HUMAN,tr|A0A7I2V2T3|A0A7I2V2T3_HUMAN,tr|E7ETK5|E7ETK5_HUMAN" 5 1945.9316 0.38 100200 12800 4 1945.936397 487.4902 Inosine-5'-monophosphate dehydrogenase 2 OS=Homo sapiens OX=9606 GN=IMPDH2 PE=1 SV=2 5.38 2356.2 - 902477 - - - 2.46 - 3.832 0.544 - 347 1 2 1 0.0048 17 0 0 0 4.38E+06 1.15E+07 - - - 4.4261 1 221125_WJC_METTL3_EV_vs_WT_F07.12801.12801.3 8.88E-08 19/64 K.KGTGIAAQTAGIAAAAR.A sp|P82912|RT11_HUMAN 1 1526.8529 1.16 100201 12801 3 1526.853591 509.9582 "28S ribosomal protein S11, mitochondrial OS=Homo sapiens OX=9606 GN=MRPS11 PE=1 SV=2" 11 2356.3 - 880006 - - - 0.4598 - 3.152 0.539 - 339.6 1 2 0 0.0007 17 0 0 0 6.03E+06 5.20E+06 - - - 7.4494 1 221125_WJC_METTL3_EV_vs_WT_F07.12802.12802.3 3.76E-07 19/64 K.K[136.11]GTGIAAQTAGIAAAAR[166.11].A sp|P82912|RT11_HUMAN 1 1544.8754 1.19 100202 12802 3 1544.877811 515.9657 "28S ribosomal protein S11, mitochondrial OS=Homo sapiens OX=9606 GN=MRPS11 PE=1 SV=2" 11 2356.3 - 815468 - - - 1.5872 - 3.574 0.558 - 523.9 1 2 0 0.0025 17 0 0 0 6.19E+06 5.20E+06 - - - 7.9782 1 221125_WJC_METTL3_EV_vs_WT_F07.12803.12803.3 7.74E-05 18/44 K.LLTHNLLSSHVR.G sp|Q9UI30|TR112_HUMAN 1 1388.7888 0.92 100203 12803 3 1388.791095 463.9369 Multifunctional methyltransferase subunit TRM112-like protein OS=Homo sapiens OX=9606 GN=TRMT112 PE=1 SV=1 9.76 2356.5 - 642818 - - - 1.6295 - 3.129 0.499 - 612.9 1 2 0 0.0023 12 0 0 0 1.66E+07 1.79E+07 - - - 7.2646 0.9941 221125_WJC_METTL3_EV_vs_WT_F07.12805.12805.4 0.00809 Dec-72 K.IEELGSELKEHYK.L "sp|Q14181|DPOA2_HUMAN,tr|A0A3B3ITS5|A0A3B3ITS5_HUMAN" 2 1573.7988 0.64 100205 12805 4 1573.801651 394.457 DNA polymerase alpha subunit B OS=Homo sapiens OX=9606 GN=POLA2 PE=1 SV=2 4.91 2356.7 - 589464 - - - 1.8192 - 1.837 0.296 - 144.1 1 2 1 0.0029 13 0 0 0 1.91E+06 3.00E+06 - - - 2.0271 1 221125_WJC_METTL3_EV_vs_WT_F07.12808.12808.2 8.08E-10 19/34 R.SSEAPATVELSSAPSAQK.R "sp|Q96AV8|E2F7_HUMAN,tr|F8VSE7|F8VSE7_HUMAN" 2 1758.8636 2.53 100208 12808 2 1758.86543 880.4391 Transcription factor E2F7 OS=Homo sapiens OX=9606 GN=E2F7 PE=1 SV=3 4.53 2357.1 - 475217 - - - 1.0558 - 3.426 0.641 - 1024.5 1 2 0 0.0019 18 0 0 0 6.11E+06 2.41E+06 - - - 6.8023 0.9996 221125_WJC_METTL3_EV_vs_WT_F07.12809.12809.4 0.000169 15/72 K.IEELGSELK[136.11]EHYK[136.11].L "sp|Q14181|DPOA2_HUMAN,tr|A0A3B3ITS5|A0A3B3ITS5_HUMAN" 2 1589.8272 0.64 100209 12809 4 1589.827364 398.4641 DNA polymerase alpha subunit B OS=Homo sapiens OX=9606 GN=POLA2 PE=1 SV=2 4.91 2357.2 - 457139 - - - 0.1107 - 2.173 0.421 - 199.5 1 2 1 0.0002 13 0 0 0 1.91E+06 3.00E+06 - - - 3.1781 0.9886 221125_WJC_METTL3_EV_vs_WT_F07.12810.12810.3 0.44 14/48 K.IEELGSELK[136.11]EHYK[136.11].L "sp|Q14181|DPOA2_HUMAN,tr|A0A3B3ITS5|A0A3B3ITS5_HUMAN" 2 1589.8272 7.77 100210 12810 3 1589.824821 530.9497 DNA polymerase alpha subunit B OS=Homo sapiens OX=9606 GN=POLA2 PE=1 SV=2 4.91 2357.3 - 445886 - - - -1.4888 - 2.096 0.207 - 171 1 2 1 -0.0024 13 0 0 0 2.03E+07 2.61E+06 - - - 2.8536 0.9999 221125_WJC_METTL3_EV_vs_WT_F07.12816.12816.3 1.04E-05 16/64 K.QLLC[160.03]GAAIGTHEDDKYR.L "sp|P12268|IMDH2_HUMAN,tr|A0A7I2YQK5|A0A7I2YQK5_HUMAN,tr|H0Y4R1|H0Y4R1_HUMAN,tr|A0A7I2V2T3|A0A7I2V2T3_HUMAN,tr|E7ETK5|E7ETK5_HUMAN" 5 1945.9316 1.07 100215 12816 3 1945.934478 649.6511 Inosine-5'-monophosphate dehydrogenase 2 OS=Homo sapiens OX=9606 GN=IMPDH2 PE=1 SV=2 5.38 2358 - 229671 - - - 1.4738 - 3.468 0.549 - 393.2 1 2 1 0.0029 17 0 0 0 1.91E+06 1.78E+06 - - - 7.8017 1 221125_WJC_METTL3_EV_vs_WT_F07.12822.12822.2 9.63E-10 19/36 R.VQDLSAGGQGSLTDSGPER.R sp|P40222|TXLNA_HUMAN 1 1872.8813 1.68 100221 12822 2 1872.886769 937.448 Alpha-taxilin OS=Homo sapiens OX=9606 GN=TXLNA PE=1 SV=3 4.03 2358.6 - 693205 - - - 2.8939 - 3.2 0.686 - 859.1 1 2 0 0.0054 19 0 0 0 8.42E+06 5.02E+06 - - - 6.9658 0.9824 221125_WJC_METTL3_EV_vs_WT_F07.12826.12826.2 0.00638 30-Sep K.GSPGSC[160.03]C[160.03]TSIVTGGSN.L sp|Q8N1N4|K2C78_HUMAN 1 1539.6294 - 100225 12826 2 1539.629762 770.822 "Keratin, type II cytoskeletal 78 OS=Homo sapiens OX=9606 GN=KRT78 PE=1 SV=2" 5.51 2359.1 - 213917 - - - 0.2631 - 1.795 0.425 - 213.3 1 1 0 0.0004 16 0 0 0 - - - - - 3.6182 1 221125_WJC_METTL3_EV_vs_WT_F07.12835.12835.3 2.66E-09 15/72 R.VQDLSAGGQGSLTDSGPER[166.11].R sp|P40222|TXLNA_HUMAN 1 1882.8896 1.31 100232 12835 3 1882.888263 628.6371 Alpha-taxilin OS=Homo sapiens OX=9606 GN=TXLNA PE=1 SV=3 4.03 2360.1 - 860862 - - - -0.7202 - 3.043 0.54 - 283.4 1 2 0 -0.0014 19 0 0 0 6.32E+06 4.82E+06 - - - 7.2941 0.9997 221125_WJC_METTL3_EV_vs_WT_F07.12836.12836.3 0.000187 Nov-44 K.KAVIFC[160.03]LSADKK.C "sp|P60981|DEST_HUMAN,tr|F6RFD5|F6RFD5_HUMAN" 2 1378.7643 1.68 100233 12836 3 1378.760872 460.5954 Destrin OS=Homo sapiens OX=9606 GN=DSTN PE=1 SV=3 9.2 2360.3 - 464525 - - - -2.4551 - 2.157 0.403 - 181.2 1 2 0 -0.0034 12 0 0 0 3.76E+06 2.24E+06 - - - 5.1629 1 221125_WJC_METTL3_EV_vs_WT_F07.12839.12839.2 2.88E-06 13/28 R.EDQSILC[160.03]TGESGAGK[136.11].T "sp|Q7Z406|MYH14_HUMAN,sp|P35580|MYH10_HUMAN,sp|P35749|MYH11_HUMAN,sp|P35579|MYH9_HUMAN,tr|Q5BKV1|Q5BKV1_HUMAN,tr|E7ERA5|E7ERA5_HUMAN,tr|A0A2R8Y4C3|A0A2R8Y4C3_HUMAN,tr|M0QY43|M0QY43_HUMAN,tr|A0A494C024|A0A494C024_HUMAN" 9 1558.7025 0.99 100236 12839 2 1558.701789 780.3585 Myosin-14 OS=Homo sapiens OX=9606 GN=MYH14 PE=1 SV=2 4.14 2360.7 - 314186 - - - -0.4254 - 2.491 0.623 - 398.9 1 2 0 -0.0007 15 0 0 0 3.31E+07 3.35E+07 - - - 5.8861 1 221125_WJC_METTL3_EV_vs_WT_F07.12840.12840.2 8.71E-08 Nov-34 R.SSEAPATVELSSAPSAQK[136.11].R "sp|Q96AV8|E2F7_HUMAN,tr|F8VSE7|F8VSE7_HUMAN" 2 1766.8778 2.53 100237 12840 2 1766.87464 884.4462 Transcription factor E2F7 OS=Homo sapiens OX=9606 GN=E2F7 PE=1 SV=3 4.53 2360.8 - 302174 - - - -1.7732 - 2.384 0.635 - 280.9 1 2 0 -0.0031 18 0 0 0 6.11E+06 2.41E+06 - - - 5.8661 0.9999 221125_WJC_METTL3_EV_vs_WT_F07.12844.12844.3 2.16E-07 16/48 R.VSISEGDDKIEYR.A "sp|P22087|FBRL_HUMAN,tr|M0R299|M0R299_HUMAN,tr|M0R0P1|M0R0P1_HUMAN,tr|M0R1H0|M0R1H0_HUMAN,tr|M0QXL5|M0QXL5_HUMAN,tr|M0R2Q4|M0R2Q4_HUMAN,tr|M0R2B0|M0R2B0_HUMAN,tr|M0R2U2|M0R2U2_HUMAN" 8 1509.7311 0.84 100239 12844 3 1509.731434 504.251 rRNA 2'-O-methyltransferase fibrillarin OS=Homo sapiens OX=9606 GN=FBL PE=1 SV=2 4.32 2361.3 - 1.11E+06 - - - 0.2199 - 3.215 0.52 - 389.6 1 2 1 0.0003 13 0 0 0 2.32E+07 2.75E+07 - - - 7.5037 1 221125_WJC_METTL3_EV_vs_WT_F07.12846.12846.4 9.63E-08 14/78 R.LVLTQEQLHQLHSR.L "sp|Q14203|DCTN1_HUMAN,tr|A0A804CDA6|A0A804CDA6_HUMAN,tr|E7EX90|E7EX90_HUMAN,tr|A0A7P0Z4C3|A0A7P0Z4C3_HUMAN,tr|E7EWF7|E7EWF7_HUMAN" 5 1700.9322 1.7 100241 12846 4 1700.930525 426.2403 Dynactin subunit 1 OS=Homo sapiens OX=9606 GN=DCTN1 PE=1 SV=3 6.92 2361.5 - 969447 - - - -0.9859 - 2.871 0.525 - 176.5 1 2 0 -0.0017 14 0 0 0 1.20E+08 7.07E+07 - - - 4.179 1 221125_WJC_METTL3_EV_vs_WT_F07.12850.12850.2 4.24E-09 16/28 R.EDQSILC[160.03]TGESGAGK.T "sp|Q7Z406|MYH14_HUMAN,sp|P35580|MYH10_HUMAN,sp|P35749|MYH11_HUMAN,sp|P35579|MYH9_HUMAN,tr|Q5BKV1|Q5BKV1_HUMAN,tr|E7ERA5|E7ERA5_HUMAN,tr|A0A2R8Y4C3|A0A2R8Y4C3_HUMAN,tr|M0QY43|M0QY43_HUMAN,tr|A0A494C024|A0A494C024_HUMAN" 9 1550.6883 0.99 100245 12850 2 1550.687724 776.3514 Myosin-14 OS=Homo sapiens OX=9606 GN=MYH14 PE=1 SV=2 4.14 2362.1 - 492602 - - - -0.3405 - 2.997 0.561 - 902.4 1 2 0 -0.0005 15 0 0 0 3.31E+07 3.35E+07 - - - 5.8829 0.9248 221125_WJC_METTL3_EV_vs_WT_F07.12854.12854.4 0.00621 Dec-78 R.K[136.11]IELFGR[166.11]PHNVQPN.W sp|Q86U44|MTA70_HUMAN 1 1665.907 0.01 100247 12854 4 1665.905541 417.484 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 8.75 2362.6 - 1.88E+06 - - - -0.8722 - 2.158 0.312 - 139.6 1 1 0 -0.0015 14 0 0 0 2.33E+06 1.76E+08 - - - 2.2212 1 221125_WJC_METTL3_EV_vs_WT_F07.12855.12855.3 1.94E-09 17/52 R.LVLTQEQLHQLHSR.L "sp|Q14203|DCTN1_HUMAN,tr|A0A804CDA6|A0A804CDA6_HUMAN,tr|E7EX90|E7EX90_HUMAN,tr|A0A7P0Z4C3|A0A7P0Z4C3_HUMAN,tr|E7EWF7|E7EWF7_HUMAN" 5 1700.9322 1.66 100248 12855 3 1700.930305 567.9847 Dynactin subunit 1 OS=Homo sapiens OX=9606 GN=DCTN1 PE=1 SV=3 6.92 2362.7 - 1.32E+06 - - - -1.1153 - 3.271 0.57 - 396 1 2 0 -0.0019 14 0 0 0 1.04E+08 6.24E+07 - - - 8.0438 1 221125_WJC_METTL3_EV_vs_WT_F07.12863.12863.3 2.25E-09 17/52 R.LVLTQEQLHQLHSR[166.11].L "sp|Q14203|DCTN1_HUMAN,tr|A0A804CDA6|A0A804CDA6_HUMAN,tr|E7EX90|E7EX90_HUMAN,tr|A0A7P0Z4C3|A0A7P0Z4C3_HUMAN,tr|E7EWF7|E7EWF7_HUMAN" 5 1710.9405 1.66 100254 12863 3 1710.940799 571.3208 Dynactin subunit 1 OS=Homo sapiens OX=9606 GN=DCTN1 PE=1 SV=3 6.92 2363.7 - 1.91E+06 - - - 0.1911 - 3.265 0.61 - 400.5 1 2 0 0.0003 14 0 0 0 1.04E+08 6.24E+07 - - - 8.4854 0.9999 221125_WJC_METTL3_EV_vs_WT_F07.12870.12870.4 4.77E-05 17/102 R.GIEQAVQSHAVAEEEAR[166.11]K[136.11].A "sp|Q16891|MIC60_HUMAN,tr|B9A067|B9A067_HUMAN,tr|C9J406|C9J406_HUMAN,tr|H7C463|H7C463_HUMAN" 4 1968.9984 3.64 100258 12870 4 1968.995495 493.2569 MICOS complex subunit MIC60 OS=Homo sapiens OX=9606 GN=IMMT PE=1 SV=1 4.91 2364.6 - 1.65E+06 - - - -1.4693 - 2.818 0.446 - 123.8 1 2 0 -0.0029 18 0 0 0 1.25E+08 3.44E+07 - - - 3.4621 1 221125_WJC_METTL3_EV_vs_WT_F07.12872.12872.4 8.28E-07 15/78 R.LVLTQEQLHQLHSR[166.11].L "sp|Q14203|DCTN1_HUMAN,tr|A0A804CDA6|A0A804CDA6_HUMAN,tr|E7EX90|E7EX90_HUMAN,tr|A0A7P0Z4C3|A0A7P0Z4C3_HUMAN,tr|E7EWF7|E7EWF7_HUMAN" 5 1710.9405 1.7 100260 12872 4 1710.938753 428.7424 Dynactin subunit 1 OS=Homo sapiens OX=9606 GN=DCTN1 PE=1 SV=3 6.92 2364.7 - 3.11E+06 - - - -1.0047 - 2.835 0.541 - 164.2 1 2 0 -0.0017 14 0 0 0 1.20E+08 7.07E+07 - - - 4.3136 0.8193 221125_WJC_METTL3_EV_vs_WT_F07.12876.12876.2 0.00694 14/16 V.QPTKRPEGR.T "sp|P84090|ERH_HUMAN,tr|G3V279|G3V279_HUMAN" 2 1067.5836 2.73 100262 12876 2 1067.582701 534.7991 Enhancer of rudimentary homolog OS=Homo sapiens OX=9606 GN=ERH PE=1 SV=1 10.84 2365.3 - 1.57E+06 - - - -0.8337 - 2.089 0.33 - 297.7 1 1 1 -0.0009 9 0 0 0 4.34E+07 1.59E+07 - - - 3.6094 1 221125_WJC_METTL3_EV_vs_WT_F07.12887.12887.2 5.08E-08 26-Dec K.STSC[160.03]VLSSAVHSQC[160.03].V "sp|Q9BQA1|MEP50_HUMAN,tr|H0Y711|H0Y711_HUMAN" 2 1521.6552 - 100269 12887 2 1521.654231 761.8349 Methylosome protein 50 OS=Homo sapiens OX=9606 GN=WDR77 PE=1 SV=1 6.45 2366.5 - 602113 - - - -0.6223 - 2.575 0.637 - 497.1 1 1 0 -0.0009 14 0 0 0 - - - - - 6.1191 0.9908 221125_WJC_METTL3_EV_vs_WT_F07.12889.12889.2 0.000657 26-Sep R.K[136.11]IELFGR[166.11]PHNVQPN.W sp|Q86U44|MTA70_HUMAN 1 1665.907 0.001 100271 12889 2 1665.906839 833.9608 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 8.75 2366.8 - 314302 - - - -0.093 - 2.139 0.473 - 180 1 1 0 -0.0002 14 0 0 0 0.00E+00 8.52E+06 - - - 4.4426 1 221125_WJC_METTL3_EV_vs_WT_F07.12892.12892.4 2.98E-09 18/96 R.VLLDHGAGINTHSNEFK.E "sp|Q8IWZ3|ANKH1_HUMAN,tr|E9PDP5|E9PDP5_HUMAN,tr|D6RHC4|D6RHC4_HUMAN" 3 1850.9275 1.88 100272 12892 4 1850.928034 463.7392 Ankyrin repeat and KH domain-containing protein 1 OS=Homo sapiens OX=9606 GN=ANKHD1 PE=1 SV=1 5.99 2367.1 - 4.59E+06 - - - 0.2826 - 3.394 0.602 - 259.9 1 2 0 0.0005 17 0 0 0 1.16E+08 6.18E+07 - - - 4.8899 0.9999 221125_WJC_METTL3_EV_vs_WT_F07.12893.12893.3 2.70E-05 Dec-36 R.DENWDKEIEK.M sp|Q96A49|SYAP1_HUMAN 1 1304.5885 1.34 100273 12893 3 1304.58857 435.8701 Synapse-associated protein 1 OS=Homo sapiens OX=9606 GN=SYAP1 PE=1 SV=1 4.18 2367.3 - 1.23E+06 - - - 0.0836 - 2.222 0.54 - 261.3 1 2 1 0.0001 10 0 0 0 6.87E+08 5.12E+08 - - - 6.8921 1 221125_WJC_METTL3_EV_vs_WT_F07.12894.12894.3 3.12E-11 18/64 R.VLLDHGAGINTHSNEFK.E "sp|Q8IWZ3|ANKH1_HUMAN,tr|E9PDP5|E9PDP5_HUMAN,tr|D6RHC4|D6RHC4_HUMAN" 3 1850.9275 1.69 100274 12894 3 1850.929628 617.9831 Ankyrin repeat and KH domain-containing protein 1 OS=Homo sapiens OX=9606 GN=ANKHD1 PE=1 SV=1 5.99 2367.3 - 2.47E+06 - - - 1.1438 - 4.138 0.683 - 327.6 1 2 0 0.0021 17 0 0 0 6.38E+07 3.78E+07 - - - 9.7421 0.9999 221125_WJC_METTL3_EV_vs_WT_F07.12895.12895.3 9.25E-06 Dec-36 R.DENWDK[136.11]EIEK[136.11].M sp|Q96A49|SYAP1_HUMAN 1 1320.6169 1.34 100275 12895 3 1320.615388 441.2129 Synapse-associated protein 1 OS=Homo sapiens OX=9606 GN=SYAP1 PE=1 SV=1 4.18 2367.4 - 1.16E+06 - - - -1.1154 - 2.483 0.535 - 243.6 1 2 1 -0.0015 10 0 0 0 6.90E+08 5.13E+08 - - - 7.1604 0.9985 221125_WJC_METTL3_EV_vs_WT_F07.12898.12898.3 0.000713 Nov-44 K.VK[136.11]VEHVVSVLEK[136.11].K sp|Q9NYU2|UGGG1_HUMAN 1 1380.8312 0.06 100278 12898 3 1380.833839 461.2843 UDP-glucose:glycoprotein glucosyltransferase 1 OS=Homo sapiens OX=9606 GN=UGGT1 PE=1 SV=3 6.73 2367.8 - 449809 - - - 1.9467 - 2.098 0.365 - 136.9 1 2 1 0.0027 12 0 0 0 1.84E+06 3.17E+07 - - - 4.6625 0.8216 221125_WJC_METTL3_EV_vs_WT_F07.12899.12899.3 2.31 Aug-44 K.YNQATQTFHQWR.D "sp|Q8N8S7|ENAH_HUMAN,tr|A0A0U1RQP7|A0A0U1RQP7_HUMAN,tr|A0A075B6E5|A0A075B6E5_HUMAN,tr|A0A0U1RRM6|A0A0U1RRM6_HUMAN" 4 1578.7328 1.56 100279 12899 3 1578.733415 527.2515 Protein enabled homolog OS=Homo sapiens OX=9606 GN=ENAH PE=1 SV=2 8.75 2367.9 - 734467 - - - 0.406 - 1.256 0.082 - 28.3 1 2 0 0.0006 12 0 0 0 7.17E+06 4.59E+06 - - - 0.0858 1 221125_WJC_METTL3_EV_vs_WT_F07.12904.12904.2 7.02E-09 14/36 F.SSC[160.03]GGGGGSFGAGGGFGSR.S sp|P04264|K2C1_HUMAN 1 1617.659 999 100282 12904 2 1617.65626 809.8368 "Keratin, type II cytoskeletal 1 OS=Homo sapiens OX=9606 GN=KRT1 PE=1 SV=6" 7.96 2368.6 - 810915 - - - -1.7043 - 3.452 0.676 - 602.8 1 1 0 -0.0028 19 0 0 0 2.20E+07 0.00E+00 - - - 7.0791 1 221125_WJC_METTL3_EV_vs_WT_F07.12905.12905.3 9.75E-09 15/64 R.NLSNNC[160.03]DTGEK[136.11]PVVTFK[136.11].E "sp|Q92540|SMG7_HUMAN,tr|E9PD50|E9PD50_HUMAN,tr|B1ALB4|B1ALB4_HUMAN" 3 1937.9488 2.2 100283 12905 3 1937.951158 646.9902 Protein SMG7 OS=Homo sapiens OX=9606 GN=SMG7 PE=1 SV=2 6.06 2368.7 - 814874 - - - 1.2286 - 2.755 0.656 - 177.1 1 2 0 0.0024 17 0 0 0 3.95E+07 1.79E+07 - - - 8.4133 0.9984 221125_WJC_METTL3_EV_vs_WT_F07.12906.12906.2 2.79E-07 18-Nov R.DENWDK[136.11]EIEK[136.11].M sp|Q96A49|SYAP1_HUMAN 1 1320.6169 1.35 100284 12906 2 1320.618803 661.3157 Synapse-associated protein 1 OS=Homo sapiens OX=9606 GN=SYAP1 PE=1 SV=1 4.18 2368.9 - 725888 - - - 1.4705 - 2.494 0.553 - 579.6 1 2 1 0.0019 10 0 0 0 1.24E+08 9.17E+07 - - - 5.6758 1 221125_WJC_METTL3_EV_vs_WT_F07.12908.12908.3 8.02E-07 14/56 R.GGSHDAPENTLAAIR.Q "sp|Q9NZC3|GDE1_HUMAN,tr|H3BU22|H3BU22_HUMAN" 2 1507.7379 0.52 100286 12908 3 1507.735347 503.5866 Glycerophosphodiester phosphodiesterase 1 OS=Homo sapiens OX=9606 GN=GDE1 PE=1 SV=1 5.32 2369.1 - 509995 - - - -1.7059 - 2.49 0.516 - 259.6 1 2 0 -0.0026 15 0 0 0 1.25E+07 2.43E+07 - - - 6.6727 1 221125_WJC_METTL3_EV_vs_WT_F07.12910.12910.3 3.27E-07 17/68 R.GIEQAVQSHAVAEEEAR[166.11]K[136.11].A "sp|Q16891|MIC60_HUMAN,tr|B9A067|B9A067_HUMAN,tr|C9J406|C9J406_HUMAN,tr|H7C463|H7C463_HUMAN" 4 1968.9984 4.15 100288 12910 3 1968.996777 657.3401 MICOS complex subunit MIC60 OS=Homo sapiens OX=9606 GN=IMMT PE=1 SV=1 4.91 2369.4 - 336761 - - - -0.8182 - 2.966 0.493 - 232.8 1 2 0 -0.0016 18 0 0 0 3.12E+07 7.51E+06 - - - 6.7433 0.9995 221125_WJC_METTL3_EV_vs_WT_F07.12917.12917.3 0.141 Dec-48 R.KTEELEEESFPER.S "sp|Q9Y2W1|TR150_HUMAN,tr|A0A3B3ITZ9|A0A3B3ITZ9_HUMAN" 2 1621.7471 2.62 100293 12917 3 1621.745563 541.5897 Thyroid hormone receptor-associated protein 3 OS=Homo sapiens OX=9606 GN=THRAP3 PE=1 SV=2 4.21 2370.2 - 1.00E+06 - - - -0.9761 - 1.953 0.308 - 144 1 2 0 -0.0016 13 0 0 0 4.51E+07 1.72E+07 - - - 3.7883 1 221125_WJC_METTL3_EV_vs_WT_F07.12921.12921.3 4.11E-10 21/64 R.VLLDHGAGINTHSNEFK[136.11].E "sp|Q8IWZ3|ANKH1_HUMAN,tr|E9PDP5|E9PDP5_HUMAN,tr|D6RHC4|D6RHC4_HUMAN" 3 1858.9417 1.69 100295 12921 3 1858.941577 620.6545 Ankyrin repeat and KH domain-containing protein 1 OS=Homo sapiens OX=9606 GN=ANKHD1 PE=1 SV=1 5.99 2370.8 - 2.49E+06 - - - -0.0721 - 4.085 0.681 - 463.4 1 2 0 -0.0001 17 0 0 0 6.37E+07 3.77E+07 - - - 9.6878 0.9989 221125_WJC_METTL3_EV_vs_WT_F07.12922.12922.2 1.54E-05 13/18 R.DENWDKEIEK.M sp|Q96A49|SYAP1_HUMAN 1 1304.5885 1.34 100296 12922 2 1304.587619 653.3015 Synapse-associated protein 1 OS=Homo sapiens OX=9606 GN=SYAP1 PE=1 SV=1 4.18 2370.8 - 2.70E+06 - - - -0.6454 - 2.714 0.498 - 845.3 1 2 1 -0.0008 10 0 0 0 1.24E+08 9.25E+07 - - - 5.5059 1 221125_WJC_METTL3_EV_vs_WT_F07.12924.12924.3 4.94E-05 15/40 R.SLGTADVHFER[166.11].K "sp|Q86V81|THOC4_HUMAN,tr|E9PB61|E9PB61_HUMAN" 2 1240.6076 0.72 100298 12924 3 1240.60855 414.5431 THO complex subunit 4 OS=Homo sapiens OX=9606 GN=ALYREF PE=1 SV=3 5.3 2371.1 - 475071 - - - 0.7899 - 2.684 0.488 - 287.4 1 2 0 0.001 11 0 0 0 2.59E+07 3.61E+07 - - - 6.7852 1 221125_WJC_METTL3_EV_vs_WT_F07.12926.12926.3 4.62E-10 15/60 V.HYEIDAC[160.03]MDSEAPGSK[136.11].D "sp|Q86U44|MTA70_HUMAN,tr|H0YFV6|H0YFV6_HUMAN" 2 1816.7487 0.17 100300 12926 3 1816.747827 606.5902 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 4.31 2371.3 - 397377 - - - -0.5081 - 2.89 0.681 - 297 1 1 0 -0.0009 16 0 0 0 1.46E+06 8.75E+06 - - - 8.8553 1 221125_WJC_METTL3_EV_vs_WT_F07.12928.12928.2 2.53E-09 16/36 R.SAAPSTLDSSSTAPAQLGK.K "sp|Q9Y5M8|SRPRB_HUMAN,tr|H7C4H2|H7C4H2_HUMAN" 2 1787.8901 1.33 100302 12928 2 1787.893445 894.9523 Signal recognition particle receptor subunit beta OS=Homo sapiens OX=9606 GN=SRPRB PE=1 SV=3 5.55 2371.6 - 208045 - - - 1.8586 - 3.071 0.543 - 641.5 1 2 0 0.0033 19 0 0 0 4.76E+07 3.59E+07 - - - 5.8091 0.999 221125_WJC_METTL3_EV_vs_WT_F07.12931.12931.3 4.23E-09 14/64 R.YGDSEFTVQSTTGHC[160.03]VH.M sp|P52597|HNRPF_HUMAN 1 1923.8057 - 100303 12931 3 1923.805501 642.2759 Heterogeneous nuclear ribonucleoprotein F OS=Homo sapiens OX=9606 GN=HNRNPF PE=1 SV=3 5.15 2372 - 1.69E+06 - - - -0.1248 - 2.4 0.686 - 136.6 1 1 0 -0.0002 17 0 0 0 - - - - - 8.3999 1 221125_WJC_METTL3_EV_vs_WT_F07.12933.12933.2 1.74E-10 13/24 R.ETENDDVTNVIQK.M sp|O15397|IPO8_HUMAN 1 1503.7053 1.74 100305 12933 2 1503.707183 752.8599 Importin-8 OS=Homo sapiens OX=9606 GN=IPO8 PE=1 SV=2 3.92 2372.3 - 555708 - - - 1.2642 - 2.844 0.626 - 764.5 1 2 0 0.0019 13 0 0 0 2.44E+07 1.40E+07 - - - 6.3466 1 221125_WJC_METTL3_EV_vs_WT_F07.12934.12934.2 4.02E-09 24-Nov R.ETENDDVTNVIQK[136.11].M sp|O15397|IPO8_HUMAN 1 1511.7195 1.74 100306 12934 2 1511.720528 756.867 Importin-8 OS=Homo sapiens OX=9606 GN=IPO8 PE=1 SV=2 3.92 2372.4 - 504489 - - - 0.6919 - 2.388 0.613 - 525.2 1 2 0 0.001 13 0 0 0 2.44E+07 1.40E+07 - - - 5.8023 0.9998 221125_WJC_METTL3_EV_vs_WT_F07.12935.12935.3 0.000291 Nov-36 R.DENWDKEIEK[136.11].M sp|Q96A49|SYAP1_HUMAN 1 1312.6027 - 100307 12935 3 1312.602151 438.5415 Synapse-associated protein 1 OS=Homo sapiens OX=9606 GN=SYAP1 PE=1 SV=1 4.18 2372.5 - 473568 - - - -0.3885 - 2.554 0.441 - 199.9 1 2 1 -0.0005 10 0 0 0 - - - - - 6.195 1 221125_WJC_METTL3_EV_vs_WT_F07.12936.12936.2 1.52E-07 17/36 R.SAAPSTLDSSSTAPAQLGK[136.11].K "sp|Q9Y5M8|SRPRB_HUMAN,tr|H7C4H2|H7C4H2_HUMAN" 2 1795.9043 1.33 100308 12936 2 1795.903178 898.9594 Signal recognition particle receptor subunit beta OS=Homo sapiens OX=9606 GN=SRPRB PE=1 SV=3 5.55 2372.6 - 472750 - - - -0.637 - 3.612 0.618 - 656.8 1 2 0 -0.0011 19 0 0 0 4.76E+07 3.59E+07 - - - 6.7626 1 221125_WJC_METTL3_EV_vs_WT_F07.12940.12940.3 1.10E-05 17/40 R.SLGTADVHFER.K "sp|Q86V81|THOC4_HUMAN,tr|E9PB61|E9PB61_HUMAN" 2 1230.5993 0.73 100310 12940 3 1230.599588 411.207 THO complex subunit 4 OS=Homo sapiens OX=9606 GN=ALYREF PE=1 SV=3 5.3 2373.2 - 961237 - - - 0.234 - 2.765 0.482 - 381.4 1 2 0 0.0003 11 0 0 0 2.62E+07 3.58E+07 - - - 6.803 0.9999 221125_WJC_METTL3_EV_vs_WT_F07.12943.12943.3 5.50E-07 14/52 K.QLIFTTEDNGKENK.T "sp|Q99598|TSNAX_HUMAN,tr|C4P0D6|C4P0D6_HUMAN,tr|C4P0D8|C4P0D8_HUMAN" 3 1635.8104 1.09 100313 12943 3 1635.810693 546.2774 Translin-associated protein X OS=Homo sapiens OX=9606 GN=TSNAX PE=1 SV=1 4.68 2373.5 - 558881 - - - 0.1699 - 2.834 0.521 - 172.9 1 2 1 0.0003 14 0 0 0 6.84E+06 6.26E+06 - - - 7.1169 1 221125_WJC_METTL3_EV_vs_WT_F07.12952.12952.3 6.66E-09 22/68 R.GGPPC[160.03]KPPAPEDEDEAWR.Q sp|P48634|PRC2A_HUMAN 1 2006.8792 1.87 100320 12952 3 2006.879008 669.967 Protein PRRC2A OS=Homo sapiens OX=9606 GN=PRRC2A PE=1 SV=3 4.18 2374.4 - 1.39E+06 - - - -0.1156 - 3.772 0.716 - 833.1 1 2 0 -0.0002 18 0 0 0 3.07E+07 1.64E+07 - - - 9.8285 1 221125_WJC_METTL3_EV_vs_WT_F07.12955.12955.3 1.71E-06 18/68 R.GGPPC[160.03]K[136.11]PPAPEDEDEAWR[166.11].Q sp|P48634|PRC2A_HUMAN 1 2024.9017 1.74 100323 12955 3 2024.895698 675.9745 Protein PRRC2A OS=Homo sapiens OX=9606 GN=PRRC2A PE=1 SV=3 4.18 2374.7 - 679690 - - - -2.969 - 3.538 0.659 - 368 1 2 0 -0.006 18 0 0 0 5.39E+07 3.09E+07 - - - 9.0319 1 221125_WJC_METTL3_EV_vs_WT_F07.12964.12964.2 8.71E-12 14/34 S.SC[160.03]GGGGGSFGAGGGFGSR.S sp|P04264|K2C1_HUMAN 1 1530.627 999 100330 12964 2 1530.625799 766.3208 "Keratin, type II cytoskeletal 1 OS=Homo sapiens OX=9606 GN=KRT1 PE=1 SV=6" 7.96 2375.8 - 508279 - - - -0.7775 - 3.064 0.783 - 547.8 1 1 0 -0.0012 18 0 0 0 1.25E+07 0.00E+00 - - - 7.5768 0.9999 221125_WJC_METTL3_EV_vs_WT_F07.12968.12968.3 0.0127 14/72 K.VNPFRPGDSEPPPAPGAQR.A "sp|Q15942|ZYX_HUMAN,tr|H0Y2Y8|H0Y2Y8_HUMAN,tr|C9IZ41|C9IZ41_HUMAN" 3 1987.9864 4.07 100333 12968 3 1987.989401 663.6694 Zyxin OS=Homo sapiens OX=9606 GN=ZYX PE=1 SV=1 6.04 2376.3 - 2.47E+06 - - - 1.498 - 2.792 0.433 - 214.7 1 2 0 0.003 19 0 0 0 2.13E+08 5.22E+07 - - - 5.8892 1 221125_WJC_METTL3_EV_vs_WT_F07.12970.12970.3 5.85E-06 16/52 K.ETTESLHGDISSLK[136.11].T "sp|P35658|NU214_HUMAN,tr|A0A0A0MSW3|A0A0A0MSW3_HUMAN,tr|A0A494BZU9|A0A494BZU9_HUMAN,tr|A0A494C1F2|A0A494C1F2_HUMAN" 4 1523.7559 1.66 100334 12970 3 1523.754035 508.9259 Nuclear pore complex protein Nup214 OS=Homo sapiens OX=9606 GN=NUP214 PE=1 SV=2 4.65 2376.5 - 797573 - - - -1.2023 - 2.356 0.473 - 379 1 2 0 -0.0018 14 0 0 0 4.19E+07 2.52E+07 - - - 6.0904 0.9999 221125_WJC_METTL3_EV_vs_WT_F07.12972.12972.4 1.31E-09 20/102 R.VLGTEAVQDPTKVEAHVR.A sp|O43395|PRPF3_HUMAN 1 1948.0378 2.31 100336 12972 4 1948.038948 488.0167 U4\U6 small nuclear ribonucleoprotein Prp3 OS=Homo sapiens OX=9606 GN=PRPF3 PE=1 SV=2 5.44 2376.7 - 1.65E+06 - - - 0.5944 - 3.663 0.57 - 363.6 1 2 1 0.0012 18 0 0 0 3.23E+08 1.40E+08 - - - 4.6317 0.9999 221125_WJC_METTL3_EV_vs_WT_F07.12973.12973.3 2.21E-09 14/48 K.HFNVNTDYQNPVR.S sp|Q9H7E2|TDRD3_HUMAN 1 1602.7539 1.23 100337 12973 3 1602.761271 535.2586 Tudor domain-containing protein 3 OS=Homo sapiens OX=9606 GN=TDRD3 PE=1 SV=1 6.74 2376.8 - 1.44E+06 - - - 4.5971 - 2.577 0.626 - 237.9 1 2 0 0.0074 13 0 0 0 1.46E+07 1.18E+07 - - - 8.0838 1 221125_WJC_METTL3_EV_vs_WT_F07.12974.12974.3 1.49E-07 16/52 K.ETTESLHGDISSLK.T "sp|P35658|NU214_HUMAN,tr|A0A0A0MSW3|A0A0A0MSW3_HUMAN,tr|A0A494BZU9|A0A494BZU9_HUMAN,tr|A0A494C1F2|A0A494C1F2_HUMAN" 4 1515.7417 1.47 100338 12974 3 1515.741711 506.2545 Nuclear pore complex protein Nup214 OS=Homo sapiens OX=9606 GN=NUP214 PE=1 SV=2 4.65 2376.9 - 1.24E+06 - - - 0.029 - 2.738 0.434 - 390.1 1 2 0 0 14 0 0 0 4.30E+07 2.93E+07 - - - 6.0554 0.9998 221125_WJC_METTL3_EV_vs_WT_F07.12975.12975.4 9.44E-09 21/102 R.VLGTEAVQDPTK[136.11]VEAHVR[166.11].A sp|O43395|PRPF3_HUMAN 1 1966.0603 2.29 100339 12975 4 1966.062398 492.5223 U4\U6 small nuclear ribonucleoprotein Prp3 OS=Homo sapiens OX=9606 GN=PRPF3 PE=1 SV=2 5.44 2377 - 821297 - - - 1.0875 - 3.799 0.439 - 405.4 1 2 1 0.0021 18 0 0 0 3.20E+08 1.39E+08 - - - 3.5037 1 221125_WJC_METTL3_EV_vs_WT_F07.12979.12979.2 1.84E-08 14/32 R.DSENLASPSEYPENGER.F "sp|P52948|NUP98_HUMAN,tr|A0A3B3ITD8|A0A3B3ITD8_HUMAN" 2 1892.8024 4.45 100343 12979 2 1892.805403 947.4085 Nuclear pore complex protein Nup98-Nup96 OS=Homo sapiens OX=9606 GN=NUP98 PE=1 SV=4 3.91 2377.5 - 241646 - - - 1.5712 - 2.918 0.726 - 438.2 1 2 0 0.003 17 0 0 0 3.97E+07 8.92E+06 - - - 7.0352 1 221125_WJC_METTL3_EV_vs_WT_F07.12980.12980.2 9.75E-08 13/36 R.AGSSTPGDAPPAVAEVQGR[166.11].S sp|Q7Z6Z7|HUWE1_HUMAN 1 1775.8678 0.99 100344 12980 2 1775.864897 888.9412 E3 ubiquitin-protein ligase HUWE1 OS=Homo sapiens OX=9606 GN=HUWE1 PE=1 SV=3 4.37 2377.6 - 166959 - - - -1.6127 - 2.408 0.668 - 337.1 1 2 0 -0.0029 19 0 0 0 8.79E+06 8.88E+06 - - - 6.1345 0.9999 221125_WJC_METTL3_EV_vs_WT_F07.12982.12982.3 1.09E-08 Nov-56 K.VC[160.03]GDSDK[136.11]GFVVINQK[136.11].G sp|P40227|TCPZ_HUMAN 1 1680.8476 0.46 100345 12982 3 1680.848361 561.2898 T-complex protein 1 subunit zeta OS=Homo sapiens OX=9606 GN=CCT6A PE=1 SV=3 5.92 2377.9 - 7.60E+06 - - - 0.4492 - 2.823 0.564 - 165.6 1 2 1 0.0008 15 0 0 0 9.16E+07 2.01E+08 - - - 7.5358 0.9999 221125_WJC_METTL3_EV_vs_WT_F07.12984.12984.3 3.08E-09 14/56 K.VC[160.03]GDSDKGFVVINQK.G sp|P40227|TCPZ_HUMAN 1 1664.8192 0.45 100347 12984 3 1664.821593 555.947 T-complex protein 1 subunit zeta OS=Homo sapiens OX=9606 GN=CCT6A PE=1 SV=3 5.92 2378 - 2.86E+06 - - - 1.4338 - 2.745 0.598 - 258.3 1 2 1 0.0024 15 0 0 0 8.99E+07 2.01E+08 - - - 7.8413 1 221125_WJC_METTL3_EV_vs_WT_F07.12985.12985.3 6.03E-11 16/72 R.SAAPSTLDSSSTAPAQLGK.K "sp|Q9Y5M8|SRPRB_HUMAN,tr|H7C4H2|H7C4H2_HUMAN" 2 1787.8901 1.26 100348 12985 3 1787.892817 596.9707 Signal recognition particle receptor subunit beta OS=Homo sapiens OX=9606 GN=SRPRB PE=1 SV=3 5.55 2378.1 - 2.17E+06 - - - 1.5074 - 3.198 0.656 - 282.9 1 2 0 0.0027 19 0 0 0 2.77E+07 2.20E+07 - - - 8.7091 1 221125_WJC_METTL3_EV_vs_WT_F07.12987.12987.3 3.62E-10 18/60 L.TC[160.03]EVDALKGTNESLER.Q "sp|P08670|VIME_HUMAN,tr|B0YJC5|B0YJC5_HUMAN,tr|B0YJC4|B0YJC4_HUMAN" 3 1820.8574 1.76 100350 12987 3 1820.860063 607.9598 Vimentin OS=Homo sapiens OX=9606 GN=VIM PE=1 SV=4 4.41 2378.3 - 827567 - - - 1.4394 - 3.764 0.634 - 446.3 1 1 1 0.0026 16 0 0 0 1.99E+07 1.13E+07 - - - 9.0088 0.9999 221125_WJC_METTL3_EV_vs_WT_F07.12988.12988.3 7.34E-08 21/68 R.VLGTEAVQDPTKVEAHVR.A sp|O43395|PRPF3_HUMAN 1 1948.0378 2.44 100351 12988 3 1948.039818 650.3532 U4\U6 small nuclear ribonucleoprotein Prp3 OS=Homo sapiens OX=9606 GN=PRPF3 PE=1 SV=2 5.44 2378.3 - 803531 - - - 1.041 - 3.638 0.593 - 555.2 1 2 1 0.002 18 0 0 0 1.27E+08 5.22E+07 - - - 8.3666 1 221125_WJC_METTL3_EV_vs_WT_F07.12990.12990.2 4.12E-07 15/28 K.VC[160.03]GDSDK[136.11]GFVVINQK[136.11].G sp|P40227|TCPZ_HUMAN 1 1680.8476 0.33 100353 12990 2 1680.849623 841.4311 T-complex protein 1 subunit zeta OS=Homo sapiens OX=9606 GN=CCT6A PE=1 SV=3 5.92 2378.6 - 300929 - - - 1.2 - 3.347 0.612 - 750.9 1 2 1 0.002 15 0 0 0 2.49E+06 7.58E+06 - - - 6.5307 1 221125_WJC_METTL3_EV_vs_WT_F07.12991.12991.2 2.39E-08 16/32 R.DSENLASPSEYPENGER[166.11].F "sp|P52948|NUP98_HUMAN,tr|A0A3B3ITD8|A0A3B3ITD8_HUMAN" 2 1902.8107 4.36 100354 12991 2 1902.813918 952.4126 Nuclear pore complex protein Nup98-Nup96 OS=Homo sapiens OX=9606 GN=NUP98 PE=1 SV=4 3.91 2378.7 - 205176 - - - 1.6917 - 3.078 0.642 - 659 1 2 0 0.0032 17 0 0 0 3.61E+07 8.26E+06 - - - 6.5459 0.9995 221125_WJC_METTL3_EV_vs_WT_F07.12999.12999.3 1.86E-06 Dec-52 K.TNETYGKLEAVQYK.T "sp|P01040|CYTA_HUMAN,tr|C9J0E4|C9J0E4_HUMAN" 2 1642.8203 47.02 100360 12999 3 1642.824906 548.614 Cystatin-A OS=Homo sapiens OX=9606 GN=CSTA PE=1 SV=1 5.81 2379.6 - 891226 - - - 2.8329 - 2.624 0.488 - 187.2 1 2 1 0.0047 14 0 0 0 4.63E+07 9.85E+05 - - - 6.5431 0.9996 221125_WJC_METTL3_EV_vs_WT_F07.13001.13001.2 0.00156 18-Sep K.YEELQVTAGR.H "sp|P48668|K2C6C_HUMAN,sp|O95678|K2C75_HUMAN,sp|P02538|K2C6A_HUMAN" 3 1164.5775 27.62 100362 13001 2 1164.579609 583.296 "Keratin, type II cytoskeletal 6C OS=Homo sapiens OX=9606 GN=KRT6C PE=1 SV=3" 4.53 2379.9 - 374151 - - - 1.8092 - 2.134 0.416 - 320 1 2 0 0.0021 10 0 0 0 6.03E+06 2.18E+05 - - - 4.2287 1 221125_WJC_METTL3_EV_vs_WT_F07.13008.13008.3 2.09E-09 19/60 L.TC[160.03]EVDALK[136.11]GTNESLER[166.11].Q "sp|P08670|VIME_HUMAN,tr|B0YJC5|B0YJC5_HUMAN,tr|B0YJC4|B0YJC4_HUMAN" 3 1838.8799 1.75 100367 13008 3 1838.88263 613.9672 Vimentin OS=Homo sapiens OX=9606 GN=VIM PE=1 SV=4 4.41 2380.8 - 933161 - - - 1.4781 - 3.005 0.646 - 574.5 1 1 1 0.0027 16 0 0 0 1.97E+07 1.13E+07 - - - 8.5647 1 221125_WJC_METTL3_EV_vs_WT_F07.13009.13009.3 7.42E-06 Dec-64 R.DSENLASPSEYPENGER.F "sp|P52948|NUP98_HUMAN,tr|A0A3B3ITD8|A0A3B3ITD8_HUMAN" 2 1892.8024 1.19 100368 13009 3 1892.802979 631.9414 Nuclear pore complex protein Nup98-Nup96 OS=Homo sapiens OX=9606 GN=NUP98 PE=1 SV=4 3.91 2380.9 - 650635 - - - 0.2906 - 2.235 0.602 - 106 1 2 0 0.0006 17 0 0 0 2.35E+07 1.97E+07 - - - 7.2833 0.9996 221125_WJC_METTL3_EV_vs_WT_F07.13010.13010.2 4.87E-08 30-Dec K.EVNVSPC[160.03]PTQPC[160.03]QLSK.G "sp|P61916|NPC2_HUMAN,tr|G3V2V8|G3V2V8_HUMAN,tr|G3V3D1|G3V3D1_HUMAN,tr|J3KMY5|J3KMY5_HUMAN,tr|E7EMS2|E7EMS2_HUMAN,tr|G3V3E8|G3V3E8_HUMAN,tr|H0YIZ1|H0YIZ1_HUMAN" 7 1842.8604 4.16 100369 13010 2 1842.866193 922.4375 NPC intracellular cholesterol transporter 2 OS=Homo sapiens OX=9606 GN=NPC2 PE=1 SV=1 6.08 2381 - 357897 - - - 3.1332 - 2.297 0.619 - 399.4 1 2 0 0.0058 16 0 0 0 6.84E+06 1.64E+06 - - - 5.6557 0.9999 221125_WJC_METTL3_EV_vs_WT_F07.13013.13013.3 4.05E-07 14/72 R.AGSSTPGDAPPAVAEVQGR.S sp|Q7Z6Z7|HUWE1_HUMAN 1 1765.8595 0.73 100372 13013 3 1765.865971 589.6271 E3 ubiquitin-protein ligase HUWE1 OS=Homo sapiens OX=9606 GN=HUWE1 PE=1 SV=3 4.37 2381.4 - 277362 - - - 3.6696 - 2.789 0.519 - 210.7 1 2 0 0.0065 19 0 0 0 6.88E+06 9.45E+06 - - - 6.8444 0.9998 221125_WJC_METTL3_EV_vs_WT_F07.13014.13014.2 2.31E-05 30-Oct K.EVNVSPC[160.03]PTQPC[160.03]QLSK[136.11].G "sp|P61916|NPC2_HUMAN,tr|G3V2V8|G3V2V8_HUMAN,tr|G3V3D1|G3V3D1_HUMAN,tr|J3KMY5|J3KMY5_HUMAN,tr|E7EMS2|E7EMS2_HUMAN,tr|G3V3E8|G3V3E8_HUMAN,tr|H0YIZ1|H0YIZ1_HUMAN" 7 1850.8746 4.16 100373 13014 2 1850.87597 926.4446 NPC intracellular cholesterol transporter 2 OS=Homo sapiens OX=9606 GN=NPC2 PE=1 SV=1 6.08 2381.5 - 134516 - - - 0.7299 - 1.882 0.485 - 260.4 1 2 0 0.0014 16 0 0 0 6.84E+06 1.64E+06 - - - 4.1774 0.9999 221125_WJC_METTL3_EV_vs_WT_F07.13019.13019.3 4.20E-07 21/68 R.VLGTEAVQDPTK[136.11]VEAHVR[166.11].A sp|O43395|PRPF3_HUMAN 1 1966.0603 2.43 100376 13019 3 1966.064411 656.3607 U4\U6 small nuclear ribonucleoprotein Prp3 OS=Homo sapiens OX=9606 GN=PRPF3 PE=1 SV=2 5.44 2382.1 - 1.57E+06 - - - 2.1113 - 3.587 0.513 - 499.2 1 2 1 0.0042 18 0 0 0 1.27E+08 5.22E+07 - - - 7.4389 1 221125_WJC_METTL3_EV_vs_WT_F07.13031.13031.3 1.70E-10 18/72 K.LNSVAAAANGLGAEKDPGR.S sp|Q9H7S9|ZN703_HUMAN 1 1809.9333 1.75 100386 13031 3 1809.937694 604.3184 Zinc finger protein 703 OS=Homo sapiens OX=9606 GN=ZNF703 PE=1 SV=1 6.07 2383.5 - 2.92E+06 - - - 2.4145 - 3.725 0.603 - 209.6 1 2 1 0.0044 19 0 0 0 4.71E+08 2.69E+08 - - - 8.4925 0.9993 221125_WJC_METTL3_EV_vs_WT_F07.13032.13032.4 0.000443 19/66 K.TRLEQEIATYRR.L "sp|Q04695|K1C17_HUMAN,sp|P02533|K1C14_HUMAN,sp|P35900|K1C20_HUMAN,sp|P08779|K1C16_HUMAN,tr|A0A3B3IS58|A0A3B3IS58_HUMAN,tr|F5GWP8|F5GWP8_HUMAN" 6 1534.8216 254.12 100387 13032 4 1534.822921 384.7127 "Keratin, type I cytoskeletal 17 OS=Homo sapiens OX=9606 GN=KRT17 PE=1 SV=2" 8.41 2383.6 - 1.19E+06 - - - 0.8679 - 2.758 0.373 - 397.1 1 2 1 0.0013 12 0 0 0 1.44E+08 5.67E+05 - - - 2.8561 0.9995 221125_WJC_METTL3_EV_vs_WT_F07.13035.13035.2 2.86E-08 Oct-36 R.AGSSTPGDAPPAVAEVQGR.S sp|Q7Z6Z7|HUWE1_HUMAN 1 1765.8595 0.99 100390 13035 2 1765.864806 883.937 E3 ubiquitin-protein ligase HUWE1 OS=Homo sapiens OX=9606 GN=HUWE1 PE=1 SV=3 4.37 2384 - 282300 - - - 3.0099 - 1.825 0.595 - 174.7 1 2 0 0.0053 19 0 0 0 8.79E+06 8.88E+06 - - - 4.913 0.9376 221125_WJC_METTL3_EV_vs_WT_F07.13037.13037.2 0.112 28-Jun K.VC[160.03]GDSDKGFVVINQK.G sp|P40227|TCPZ_HUMAN 1 1664.8192 0.33 100392 13037 2 1664.823244 833.4169 T-complex protein 1 subunit zeta OS=Homo sapiens OX=9606 GN=CCT6A PE=1 SV=3 5.92 2384.3 - 221754 - - - 2.4255 - 1.41 0.262 - 98.8 1 2 1 0.004 15 0 0 0 2.49E+06 7.58E+06 - - - 1.8196 1 221125_WJC_METTL3_EV_vs_WT_F07.13038.13038.2 9.59E-09 26-Sep K.TNETYGKLEAVQYK.T "sp|P01040|CYTA_HUMAN,tr|C9J0E4|C9J0E4_HUMAN" 2 1642.8203 999 100393 13038 2 1642.822912 822.4174 Cystatin-A OS=Homo sapiens OX=9606 GN=CSTA PE=1 SV=1 5.81 2384.4 - 179909 - - - 1.6192 - 2.531 0.592 - 258.9 1 2 1 0.0027 14 0 0 0 1.98E+06 0.00E+00 - - - 5.743 1 221125_WJC_METTL3_EV_vs_WT_F07.13048.13048.3 1.24E-07 17/60 K.K[136.11]PLTSNC[160.03]TIQIATPGK[136.11].G "sp|Q15061|WDR43_HUMAN,tr|C9IZK7|C9IZK7_HUMAN" 2 1743.9524 0.84 100401 13048 3 1743.954859 582.3247 WD repeat-containing protein 43 OS=Homo sapiens OX=9606 GN=WDR43 PE=1 SV=3 9.31 2385.4 - 363320 - - - 1.4066 - 3.586 0.574 - 357.5 1 2 0 0.0025 16 0 0 0 4.02E+07 4.76E+07 - - - 8.2156 1 221125_WJC_METTL3_EV_vs_WT_F07.13050.13050.2 5.32E-11 15/34 R.SPSDSSTASTPVAEQIER.A "sp|Q16643|DREB_HUMAN,tr|D6R9Q9|D6R9Q9_HUMAN" 2 1860.8701 0.99 100403 13050 2 1860.873991 931.4423 Drebrin OS=Homo sapiens OX=9606 GN=DBN1 PE=1 SV=4 4.14 2385.7 - 251983 - - - 2.0829 - 3.393 0.692 - 578.8 1 2 0 0.0039 18 0 0 0 9.63E+06 9.75E+06 - - - 7.1545 1 221125_WJC_METTL3_EV_vs_WT_F07.13051.13051.2 9.91E-10 16/34 R.SPSDSSTASTPVAEQIER[166.11].A "sp|Q16643|DREB_HUMAN,tr|D6R9Q9|D6R9Q9_HUMAN" 2 1870.8784 0.99 100404 13051 2 1870.883714 936.4465 Drebrin OS=Homo sapiens OX=9606 GN=DBN1 PE=1 SV=4 4.14 2385.8 - 236748 - - - 2.8484 - 3.626 0.705 - 713.5 1 2 0 0.0053 18 0 0 0 9.63E+06 9.75E+06 - - - 7.4134 0.9044 221125_WJC_METTL3_EV_vs_WT_F07.13052.13052.3 0.000762 Oct-36 Y.SK[136.11]DNEGSWFR[166.11].S "sp|Q9BPW8|NIPS1_HUMAN,tr|H7C2U6|H7C2U6_HUMAN,tr|F8WCR5|F8WCR5_HUMAN" 3 1242.5748 1.3 100405 13052 3 1242.573334 415.1989 Protein NipSnap homolog 1 OS=Homo sapiens OX=9606 GN=NIPSNAP1 PE=1 SV=1 5.79 2386 - 203427 - - - -1.1959 - 1.927 0.369 - 136 1 1 1 -0.0015 10 0 0 0 1.63E+07 1.26E+07 - - - 4.5693 0.9987 221125_WJC_METTL3_EV_vs_WT_F07.13055.13055.3 0.0205 17/44 K.TRLEQEIATYRR.L "sp|Q04695|K1C17_HUMAN,sp|P02533|K1C14_HUMAN,sp|P35900|K1C20_HUMAN,sp|P08779|K1C16_HUMAN,tr|A0A3B3IS58|A0A3B3IS58_HUMAN,tr|F5GWP8|F5GWP8_HUMAN" 6 1534.8216 5617.83 100406 13055 3 1534.824404 512.6145 "Keratin, type I cytoskeletal 17 OS=Homo sapiens OX=9606 GN=KRT17 PE=1 SV=2" 8.41 2386.4 - 1.09E+07 - - - 1.8341 - 2.692 0.308 - 260.1 1 2 1 0.0028 12 0 0 0 3.18E+08 5.66E+04 - - - 4.718 1 221125_WJC_METTL3_EV_vs_WT_F07.13059.13059.3 5.32E-11 20/60 L.GTEAVQDPTKVEAHVR.A sp|O43395|PRPF3_HUMAN 1 1735.8853 9.93 100410 13059 3 1735.892518 579.6357 U4\U6 small nuclear ribonucleoprotein Prp3 OS=Homo sapiens OX=9606 GN=PRPF3 PE=1 SV=2 5.45 2386.7 - 874100 - - - 4.1512 - 4.1 0.624 - 840.1 1 1 1 0.0072 16 0 0 0 9.83E+06 9.90E+05 - - - 9.1154 0.9976 221125_WJC_METTL3_EV_vs_WT_F07.13060.13060.3 0.00622 Oct-40 R.NSYEPIKEFQK.E sp|Q5VT06|CE350_HUMAN 1 1381.6878 2.26 100411 13060 3 1381.689317 461.5699 Centrosome-associated protein 350 OS=Homo sapiens OX=9606 GN=CEP350 PE=1 SV=1 6.14 2386.8 - 608258 - - - 1.1117 - 1.869 0.322 - 139.1 1 2 1 0.0015 11 0 0 0 1.08E+07 4.80E+06 - - - 3.9062 0.9995 221125_WJC_METTL3_EV_vs_WT_F07.13061.13061.3 2.69E-05 Nov-40 K.DR[166.11]VTDALNATR[166.11].A "sp|P10809|CH60_HUMAN,tr|A0A7I2V2X6|A0A7I2V2X6_HUMAN,tr|A0A7I2YQK6|A0A7I2YQK6_HUMAN,tr|A0A7I2V599|A0A7I2V599_HUMAN" 4 1250.6482 1.37 100412 13061 3 1250.64977 417.89 "60 kDa heat shock protein, mitochondrial OS=Homo sapiens OX=9606 GN=HSPD1 PE=1 SV=2" 5.96 2386.9 - 538331 - - - 1.253 - 2.334 0.385 - 231.8 1 2 1 0.0016 11 0 0 0 2.31E+07 1.68E+07 - - - 5.2398 1 221125_WJC_METTL3_EV_vs_WT_F07.13066.13066.2 5.48E-07 17/36 K.LNSVAAAANGLGAEKDPGR.S sp|Q9H7S9|ZN703_HUMAN 1 1809.9333 1.84 100417 13066 2 1809.93825 905.9739 Zinc finger protein 703 OS=Homo sapiens OX=9606 GN=ZNF703 PE=1 SV=1 6.07 2387.6 - 356835 - - - 2.7216 - 3.852 0.622 - 363.4 1 2 1 0.0049 19 0 0 0 9.90E+06 5.38E+06 - - - 6.9491 0.9998 221125_WJC_METTL3_EV_vs_WT_F07.13073.13073.3 5.24E-06 Dec-40 K.DRVTDALNATR.A "sp|P10809|CH60_HUMAN,tr|A0A7I2V2X6|A0A7I2V2X6_HUMAN,tr|A0A7I2YQK6|A0A7I2YQK6_HUMAN,tr|A0A7I2V599|A0A7I2V599_HUMAN" 4 1230.6317 1.37 100422 13073 3 1230.632187 411.2178 "60 kDa heat shock protein, mitochondrial OS=Homo sapiens OX=9606 GN=HSPD1 PE=1 SV=2" 5.96 2388.4 - 1.57E+06 - - - 0.4258 - 2.125 0.501 - 240.6 1 2 1 0.0005 11 0 0 0 2.31E+07 1.68E+07 - - - 6.2668 1 221125_WJC_METTL3_EV_vs_WT_F07.13076.13076.3 2.45E-06 19/60 K.KPLTSNC[160.03]TIQIATPGK.G "sp|Q15061|WDR43_HUMAN,tr|C9IZK7|C9IZK7_HUMAN" 2 1727.924 0.76 100425 13076 3 1727.928301 576.9819 WD repeat-containing protein 43 OS=Homo sapiens OX=9606 GN=WDR43 PE=1 SV=3 9.31 2388.6 - 901320 - - - 2.4856 - 3.606 0.603 - 442.4 1 2 0 0.0043 16 0 0 0 4.07E+07 5.35E+07 - - - 8.5526 0.9999 221125_WJC_METTL3_EV_vs_WT_F07.13082.13082.2 0.000368 24-Nov R.DALNQATSQVESK.Q "sp|Q9P2E9|RRBP1_HUMAN,tr|A0A087WVV2|A0A087WVV2_HUMAN,tr|F8W7S5|F8W7S5_HUMAN" 3 1389.6736 1.57 100431 13082 2 1389.673798 695.8441 Ribosome-binding protein 1 OS=Homo sapiens OX=9606 GN=RRBP1 PE=1 SV=5 4.37 2389.4 - 371271 - - - 0.1518 - 2.593 0.519 - 555.1 1 2 0 0.0002 13 0 0 0 1.02E+07 6.50E+06 - - - 5.3197 0.9995 221125_WJC_METTL3_EV_vs_WT_F07.13091.13091.4 0.000902 18/108 K.LNSVAAAANGLGAEKDPGR.S sp|Q9H7S9|ZN703_HUMAN 1 1809.9333 1.53 100439 13091 4 1809.933625 453.4906 Zinc finger protein 703 OS=Homo sapiens OX=9606 GN=ZNF703 PE=1 SV=1 6.07 2390.3 - 823372 - - - 0.1663 - 3.393 0.397 - 141.7 1 2 1 0.0003 19 0 0 0 7.44E+06 4.85E+06 - - - 3.0947 0.9907 221125_WJC_METTL3_EV_vs_WT_F07.13093.13093.3 0.000599 15/44 R.K[136.11]HAASDVDLEIE.S "sp|Q86U44|MTA70_HUMAN,tr|F5H6D8|F5H6D8_HUMAN,tr|H0YFV6|H0YFV6_HUMAN,tr|B4DTN4|B4DTN4_HUMAN" 4 1333.6605 0.04 100441 13093 3 1333.660012 445.5608 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 4.53 2390.5 - 656877 - - - -0.3734 - 2.627 0.366 - 211.9 1 1 0 -0.0005 12 0 0 0 3.06E+05 7.64E+06 - - - 5.2976 1 221125_WJC_METTL3_EV_vs_WT_F07.13094.13094.3 8.52E-08 18/48 K.C[160.03]DSVC[160.03]VNPYHYER.V "sp|Q13485|SMAD4_HUMAN,tr|K7EIU8|K7EIU8_HUMAN,tr|K7EIJ2|K7EIJ2_HUMAN,tr|K7ES96|K7ES96_HUMAN" 4 1697.6926 2.73 100442 13094 3 1697.692088 566.9048 Mothers against decapentaplegic homolog 4 OS=Homo sapiens OX=9606 GN=SMAD4 PE=1 SV=1 5.32 2390.6 - 490263 - - - -0.3169 - 3.065 0.654 - 657.7 1 2 0 -0.0005 13 0 0 0 1.61E+07 5.89E+06 - - - 8.8681 0.9992 221125_WJC_METTL3_EV_vs_WT_F07.13098.13098.4 0.000671 13/78 K.LKEENFFGPKEEVK.L sp|Q9NZI8|IF2B1_HUMAN 1 1692.8723 1.6 100444 13098 4 1692.8716 424.2253 Insulin-like growth factor 2 mRNA-binding protein 1 OS=Homo sapiens OX=9606 GN=IGF2BP1 PE=1 SV=2 4.95 2391.2 - 911530 - - - -0.4058 - 1.945 0.38 - 99.8 1 2 2 -0.0007 14 0 0 0 1.61E+08 1.01E+08 - - - 2.7754 0.9974 221125_WJC_METTL3_EV_vs_WT_F07.13104.13104.3 0.0302 Oct-52 K.LK[136.11]EENFFGPK[136.11]EEVK[136.11].L sp|Q9NZI8|IF2B1_HUMAN 1 1716.9149 1.77 100450 13104 3 1716.915212 573.3122 Insulin-like growth factor 2 mRNA-binding protein 1 OS=Homo sapiens OX=9606 GN=IGF2BP1 PE=1 SV=2 4.95 2391.8 - 506297 - - - 0.1893 - 2.064 0.293 - 58.6 1 2 2 0.0003 14 0 0 0 1.43E+08 8.08E+07 - - - 3.7323 0.9989 221125_WJC_METTL3_EV_vs_WT_F07.13107.13107.2 2.83E-06 Oct-36 K.LNSVAAAANGLGAEK[136.11]DPGR[166.11].S sp|Q9H7S9|ZN703_HUMAN 1 1827.9558 1.84 100453 13107 2 1827.956728 914.9852 Zinc finger protein 703 OS=Homo sapiens OX=9606 GN=ZNF703 PE=1 SV=1 6.07 2392.2 - 442340 - - - 0.511 - 2.453 0.577 - 109.2 1 2 1 0.0009 19 0 0 0 9.90E+06 5.38E+06 - - - 5.5085 0.9999 221125_WJC_METTL3_EV_vs_WT_F07.13109.13109.3 0.00111 14/72 K.VNPFR[166.11]PGDSEPPPAPGAQR[166.11].A "sp|Q15942|ZYX_HUMAN,tr|H0Y2Y8|H0Y2Y8_HUMAN,tr|C9IZ41|C9IZ41_HUMAN" 3 2008.003 2.29 100455 13109 3 2008.001555 670.3416 Zyxin OS=Homo sapiens OX=9606 GN=ZYX PE=1 SV=1 6.04 2392.5 - 342810 - - - -0.7012 - 2.633 0.443 - 170.4 1 2 0 -0.0014 19 0 0 0 2.61E+07 1.14E+07 - - - 5.8571 0.9994 221125_WJC_METTL3_EV_vs_WT_F07.13115.13115.4 0.000203 Dec-78 K.LK[136.11]EENFFGPK[136.11]EEVK[136.11].L sp|Q9NZI8|IF2B1_HUMAN 1 1716.9149 1.61 100459 13115 4 1716.914658 430.236 Insulin-like growth factor 2 mRNA-binding protein 1 OS=Homo sapiens OX=9606 GN=IGF2BP1 PE=1 SV=2 4.95 2393.1 - 1.64E+06 - - - -0.1334 - 2.64 0.387 - 85.3 1 2 2 -0.0002 14 0 0 0 1.61E+08 9.99E+07 - - - 2.9477 1 221125_WJC_METTL3_EV_vs_WT_F07.13122.13122.3 9.24E-07 17/56 R.DNGLLAK[136.11]PTHGDIIR[166.11].F sp|P04181|OAT_HUMAN 1 1636.9016 1.23 100466 13122 3 1636.904107 546.6411 "Ornithine aminotransferase, mitochondrial OS=Homo sapiens OX=9606 GN=OAT PE=1 SV=1" 6.75 2393.9 - 292909 - - - 1.5474 - 3.343 0.491 - 389.6 1 2 0 0.0025 15 0 0 0 1.58E+07 1.29E+07 - - - 7.1626 1 221125_WJC_METTL3_EV_vs_WT_F07.13125.13125.3 8.84E-05 20/76 R.AGGDAEPR[166.11]PAEPPAWAGGAR[166.11].P sp|Q96HS1|PGAM5_HUMAN 1 1951.9404 2.09 100467 13125 3 1951.940609 651.6541 "Serine\threonine-protein phosphatase PGAM5, mitochondrial OS=Homo sapiens OX=9606 GN=PGAM5 PE=1 SV=2" 4.68 2394.3 - 1.92E+06 - - - 0.1265 - 3.815 0.605 - 555.2 1 1 0 0.0002 20 0 0 0 1.06E+08 5.06E+07 - - - 8.5334 1 221125_WJC_METTL3_EV_vs_WT_F07.13127.13127.3 6.93E-06 14/48 K.KPWQLQGEVTAQK.R "sp|O00566|MPP10_HUMAN,tr|U3KQ48|U3KQ48_HUMAN" 2 1511.8096 1.14 100469 13127 3 1511.809862 504.9438 U3 small nucleolar ribonucleoprotein protein MPP10 OS=Homo sapiens OX=9606 GN=MPHOSPH10 PE=1 SV=2 8.59 2394.4 - 1.18E+06 - - - 0.1554 - 2.931 0.501 - 422.3 1 2 0 0.0002 13 0 0 0 2.63E+07 2.30E+07 - - - 7.0412 0.9998 221125_WJC_METTL3_EV_vs_WT_F07.13129.13129.3 0.000905 15/60 R.GRFPESSAVQSSSFER.R "sp|Q9NWH9|SLTM_HUMAN,tr|H0YMM0|H0YMM0_HUMAN,tr|H7C3F4|H7C3F4_HUMAN" 3 1769.8333 1.44 100471 13129 3 1769.835528 590.9517 SAFB-like transcription modulator OS=Homo sapiens OX=9606 GN=SLTM PE=1 SV=2 6.14 2394.7 - 602178 - - - 1.2724 - 2.929 0.478 - 333.9 1 2 1 0.0023 16 0 0 0 2.34E+07 1.63E+07 - - - 6.626 0.9988 221125_WJC_METTL3_EV_vs_WT_F07.13133.13133.3 2.31E-07 18/44 L.RQSVEADINGLR.R "sp|P13645|K1C10_HUMAN,sp|Q2M2I5|K1C24_HUMAN,sp|P13646|K1C13_HUMAN,tr|A0A1B0GVI3|A0A1B0GVI3_HUMAN,tr|K7EMD9|K7EMD9_HUMAN,tr|K7ERE3|K7ERE3_HUMAN" 6 1356.711 166.89 100473 13133 3 1356.711199 453.2443 "Keratin, type I cytoskeletal 10 OS=Homo sapiens OX=9606 GN=KRT10 PE=1 SV=6" 6.07 2395.2 - 4.50E+06 - - - 0.1644 - 3.336 0.543 - 734 1 1 0 0.0002 12 0 0 0 1.09E+09 6.53E+06 - - - 7.9333 1 221125_WJC_METTL3_EV_vs_WT_F07.13135.13135.3 4.21E-06 14/52 K.K[136.11]AEHQVGEDGFLLK[136.11].L "sp|P51692|STA5B_HUMAN,sp|P42229|STA5A_HUMAN,tr|C9J4I3|C9J4I3_HUMAN,tr|A0A7I2YQY3|A0A7I2YQY3_HUMAN,tr|K7EK35|K7EK35_HUMAN,tr|A0A7I2V380|A0A7I2V380_HUMAN,tr|A0A7I2YQF1|A0A7I2YQF1_HUMAN" 7 1585.8435 0.25 100475 13135 3 1585.84479 529.6218 Signal transducer and activator of transcription 5B OS=Homo sapiens OX=9606 GN=STAT5B PE=1 SV=2 5.45 2395.3 - 836899 - - - 0.809 - 2.968 0.506 - 238.7 1 2 0 0.0013 14 0 0 0 4.62E+06 1.87E+07 - - - 7.0721 0.9998 221125_WJC_METTL3_EV_vs_WT_F07.13136.13136.3 0.0122 Dec-68 R.KAVTAFSSTETGSAEGFK.S tr|A0A804HKC3|A0A804HKC3_HUMAN 1 1816.8843 4.6 100476 13136 3 1816.884934 606.6354 Protein PRRC2B (Fragment) OS=Homo sapiens OX=9606 GN=PRRC2B PE=4 SV=1 6.14 2395.4 - 745186 - - - 0.344 - 2.279 0.354 - 151.7 1 2 0 0.0006 18 0 0 0 3.15E+07 6.85E+06 - - - 4.5378 1 221125_WJC_METTL3_EV_vs_WT_F07.13137.13137.3 6.17E-09 16/68 R.ELQSMADQEQVSPAAIKK.T "sp|P32322|P5CR1_HUMAN,tr|E2QRB3|E2QRB3_HUMAN" 2 1971.9935 3.92 100477 13137 3 1971.995325 658.3385 "Pyrroline-5-carboxylate reductase 1, mitochondrial OS=Homo sapiens OX=9606 GN=PYCR1 PE=1 SV=2" 4.68 2395.5 - 629024 - - - 0.9042 - 2.753 0.623 - 246.1 1 2 0 0.0018 18 0 0 0 1.70E+07 4.33E+06 - - - 8.007 1 221125_WJC_METTL3_EV_vs_WT_F07.13143.13143.2 8.84E-08 20/22 L.RQSVEADINGLR.R "sp|P13645|K1C10_HUMAN,sp|Q2M2I5|K1C24_HUMAN,sp|P13646|K1C13_HUMAN,tr|A0A1B0GVI3|A0A1B0GVI3_HUMAN,tr|K7EMD9|K7EMD9_HUMAN,tr|K7ERE3|K7ERE3_HUMAN" 6 1356.711 2689.37 100481 13143 2 1356.710801 679.3628 "Keratin, type I cytoskeletal 10 OS=Homo sapiens OX=9606 GN=KRT10 PE=1 SV=6" 6.07 2396.3 - 1.70E+06 - - - -0.129 - 3.467 0.515 - 629.4 1 1 0 -0.0002 12 0 0 0 2.49E+08 9.27E+04 - - - 6.116 0.999 221125_WJC_METTL3_EV_vs_WT_F07.13145.13145.4 0.000995 18/84 R.DNGLLAKPTHGDIIR.F sp|P04181|OAT_HUMAN 1 1618.8791 1.4 100483 13145 4 1618.876793 405.7271 "Ornithine aminotransferase, mitochondrial OS=Homo sapiens OX=9606 GN=OAT PE=1 SV=1" 6.75 2396.5 - 554612 - - - -1.4275 - 2.986 0.281 - 261.5 1 2 0 -0.0023 15 0 0 0 1.17E+07 8.35E+06 - - - 2.0626 1 221125_WJC_METTL3_EV_vs_WT_F07.13146.13146.4 4.64E-06 16/78 K.K[136.11]AEHQVGEDGFLLK[136.11].L "sp|P51692|STA5B_HUMAN,sp|P42229|STA5A_HUMAN,tr|C9J4I3|C9J4I3_HUMAN,tr|A0A7I2YQY3|A0A7I2YQY3_HUMAN,tr|K7EK35|K7EK35_HUMAN,tr|A0A7I2V380|A0A7I2V380_HUMAN,tr|A0A7I2YQF1|A0A7I2YQF1_HUMAN" 7 1585.8435 0.02 100484 13146 4 1585.842044 397.4682 Signal transducer and activator of transcription 5B OS=Homo sapiens OX=9606 GN=STAT5B PE=1 SV=2 5.45 2396.6 - 430739 - - - -0.9225 - 2.733 0.478 - 159.4 1 2 0 -0.0015 14 0 0 0 1.35E+05 5.73E+06 - - - 3.752 1 221125_WJC_METTL3_EV_vs_WT_F07.13147.13147.2 1.90E-07 30-Oct K.TNSLTDSTC[160.03]DDSSEFK[136.11].S "sp|O75592|MYCB2_HUMAN,tr|A0A804HL12|A0A804HL12_HUMAN,tr|A0A499FJI4|A0A499FJI4_HUMAN,tr|A0A804HIR9|A0A804HIR9_HUMAN,tr|A0A804HJ25|A0A804HJ25_HUMAN,tr|A0A804HKQ1|A0A804HKQ1_HUMAN" 6 1813.7404 0.91 100485 13147 2 1813.741168 907.8775 E3 ubiquitin-protein ligase MYCBP2 OS=Homo sapiens OX=9606 GN=MYCBP2 PE=1 SV=4 3.84 2396.8 - 204636 - - - 0.4493 - 2.448 0.662 - 236 1 2 0 0.0008 16 0 0 0 2.89E+06 3.17E+06 - - - 6.1313 0.9999 221125_WJC_METTL3_EV_vs_WT_F07.13151.13151.3 6.53E-05 17/40 K.LK[136.11]VSELK[136.11]EELK[136.11].K "sp|Q00839|HNRPU_HUMAN,tr|A0A1W2PPS1|A0A1W2PPS1_HUMAN,tr|A0A1X7SBS1|A0A1X7SBS1_HUMAN" 3 1338.8185 0.89 100487 13151 3 1338.818272 447.2801 Heterogeneous nuclear ribonucleoprotein U OS=Homo sapiens OX=9606 GN=HNRNPU PE=1 SV=6 6.23 2397.3 - 1.76E+06 - - - -0.1464 - 3.089 0.524 - 260 1 2 2 -0.0002 11 0 0 0 1.67E+08 1.87E+08 - - - 7.586 1 221125_WJC_METTL3_EV_vs_WT_F07.13152.13152.3 1.23E-06 20/56 R.DNGLLAKPTHGDIIR.F sp|P04181|OAT_HUMAN 1 1618.8791 1.23 100488 13152 3 1618.878685 540.6336 "Ornithine aminotransferase, mitochondrial OS=Homo sapiens OX=9606 GN=OAT PE=1 SV=1" 6.75 2397.4 - 951658 - - - -0.2588 - 3.73 0.508 - 579.4 1 2 0 -0.0004 15 0 0 0 1.58E+07 1.29E+07 - - - 7.6386 0.9999 221125_WJC_METTL3_EV_vs_WT_F07.13154.13154.3 2.32E-06 18/40 K.LKVSELKEELK.K "sp|Q00839|HNRPU_HUMAN,tr|A0A1W2PPS1|A0A1W2PPS1_HUMAN,tr|A0A1X7SBS1|A0A1X7SBS1_HUMAN" 3 1314.7759 0.89 100490 13154 3 1314.775606 439.2659 Heterogeneous nuclear ribonucleoprotein U OS=Homo sapiens OX=9606 GN=HNRNPU PE=1 SV=6 6.23 2397.7 - 766061 - - - -0.1993 - 3.378 0.502 - 318.9 1 2 2 -0.0003 11 0 0 0 1.67E+08 1.87E+08 - - - 7.5948 0.9997 221125_WJC_METTL3_EV_vs_WT_F07.13160.13160.3 0.00117 Nov-44 K.YSIWC[160.03]STEHGNK.R "sp|Q9BYJ9|YTHD1_HUMAN,sp|Q7Z739|YTHD3_HUMAN,tr|A0A087X0Q1|A0A087X0Q1_HUMAN,tr|A0A024R7W5|A0A024R7W5_HUMAN,tr|A0A087WY31|A0A087WY31_HUMAN" 5 1480.6405 1.37 100494 13160 3 1480.638968 494.5541 YTH domain-containing family protein 1 OS=Homo sapiens OX=9606 GN=YTHDF1 PE=1 SV=1 6.74 2398.4 - 969952 - - - -1.0435 - 1.79 0.37 - 105.1 1 2 0 -0.0015 12 0 0 0 2.34E+07 1.71E+07 - - - 4.2785 0.9981 221125_WJC_METTL3_EV_vs_WT_F07.13168.13168.3 0.0286 Jul-44 K.YSIWC[160.03]STEHGNK[136.11].R "sp|Q9BYJ9|YTHD1_HUMAN,sp|Q7Z739|YTHD3_HUMAN,tr|A0A087X0Q1|A0A087X0Q1_HUMAN,tr|A0A024R7W5|A0A024R7W5_HUMAN,tr|A0A087WY31|A0A087WY31_HUMAN" 5 1488.6547 1.37 100499 13168 3 1488.653329 497.2255 YTH domain-containing family protein 1 OS=Homo sapiens OX=9606 GN=YTHDF1 PE=1 SV=1 6.74 2399.3 - 891006 - - - -0.9297 - 1.466 0.292 - 36.4 1 2 0 -0.0014 12 0 0 0 2.34E+07 1.71E+07 - - - 2.8555 0.9867 221125_WJC_METTL3_EV_vs_WT_F07.13169.13169.2 0.597 14-May R.EGEAGPAR.S sp|Q9NVR5|KTU_HUMAN 1 785.3668 6.39 100500 13169 2 785.36587 393.6907 Protein kintoun OS=Homo sapiens OX=9606 GN=DNAAF2 PE=1 SV=2 4.53 2399.5 - 491138 - - - -1.16 - 1.062 0.186 - 86.8 1 2 0 -0.0009 8 0 0 0 7.40E+06 1.16E+06 - - - 0.5959 0.9786 221125_WJC_METTL3_EV_vs_WT_F07.13173.13173.2 5.96 14-Jul K.SISISVAR.G sp|P04264|K2C1_HUMAN 1 831.4814 211.98 100502 13173 2 831.480719 416.748 "Keratin, type II cytoskeletal 1 OS=Homo sapiens OX=9606 GN=KRT1 PE=1 SV=6" 9.47 2400 - 737902 - - - -0.8395 - 1.276 0.056 - 132.5 1 2 0 -0.0007 8 0 0 0 1.40E+07 6.59E+04 - - - 0.1895 0.9996 221125_WJC_METTL3_EV_vs_WT_F07.13174.13174.3 0.00374 Sep-48 R.TDSTSDGR[166.11]PAWMR[166.11].T "sp|Q14204|DYHC1_HUMAN,tr|A0A7P0T9C4|A0A7P0T9C4_HUMAN,tr|A0A2R8Y706|A0A2R8Y706_HUMAN,tr|A0A7P0TAW9|A0A7P0TAW9_HUMAN,tr|A0A7P0TA13|A0A7P0TA13_HUMAN,tr|A0A7P0T7V5|A0A7P0T7V5_HUMAN,tr|A0A7P0T9R4|A0A7P0T9R4_HUMAN,tr|A0A2R8Y5T0|A0A2R8Y5T0_HUMAN" 8 1498.6738 0.81 100503 13174 3 1498.67331 500.5652 Cytoplasmic dynein 1 heavy chain 1 OS=Homo sapiens OX=9606 GN=DYNC1H1 PE=1 SV=5 5.63 2400.1 - 483112 - - - -0.3043 - 1.804 0.347 - 136.3 1 2 0 -0.0005 13 0 0 0 1.36E+07 1.68E+07 - - - 4.0083 0.926 221125_WJC_METTL3_EV_vs_WT_F07.13175.13175.4 0.575 Sep-72 K.LVEHGLNETIHIR.G sp|Q7Z3B4|NUP54_HUMAN 1 1529.8314 1.63 100504 13175 4 1529.829468 383.4651 Nucleoporin p54 OS=Homo sapiens OX=9606 GN=NUP54 PE=1 SV=2 6 2400.2 - 250501 - - - -1.2792 - 1.761 0.121 - 47.7 1 2 0 -0.002 13 0 0 0 8.78E+06 5.39E+06 - - - 0.4885 1 221125_WJC_METTL3_EV_vs_WT_F07.13179.13179.2 6.60E-10 16/26 R.K[136.11]LDDAIEDC[160.03]TNAVK[136.11].L "sp|Q99615|DNJC7_HUMAN,tr|A0A6I8PRZ0|A0A6I8PRZ0_HUMAN,tr|A0A6I8PLE7|A0A6I8PLE7_HUMAN,tr|A0A6I8PR89|A0A6I8PR89_HUMAN,tr|A0A6I8PIK4|A0A6I8PIK4_HUMAN,tr|A0A6I8PUC2|A0A6I8PUC2_HUMAN,tr|A0A6I8PS32|A0A6I8PS32_HUMAN,tr|A0A6I8PUD4|A0A6I8PUD4_HUMAN,tr|A0A6I8PU73|A0A6I8PU73_HUMAN,tr|A0A6I8PU89|A0A6I8PU89_HUMAN" 10 1606.7843 0.64 100506 13179 2 1606.780524 804.3994 DnaJ homolog subfamily C member 7 OS=Homo sapiens OX=9606 GN=DNAJC7 PE=1 SV=2 4.23 2400.8 - 892333 - - - -2.3731 - 3.304 0.589 - 632.1 1 2 0 -0.0038 14 0 0 0 1.18E+07 1.84E+07 - - - 6.3893 1 221125_WJC_METTL3_EV_vs_WT_F07.13180.13180.2 3.19E-06 14/26 R.KLDDAIEDC[160.03]TNAVK.L "sp|Q99615|DNJC7_HUMAN,tr|A0A6I8PRZ0|A0A6I8PRZ0_HUMAN,tr|A0A6I8PLE7|A0A6I8PLE7_HUMAN,tr|A0A6I8PR89|A0A6I8PR89_HUMAN,tr|A0A6I8PIK4|A0A6I8PIK4_HUMAN,tr|A0A6I8PUC2|A0A6I8PUC2_HUMAN,tr|A0A6I8PS32|A0A6I8PS32_HUMAN,tr|A0A6I8PUD4|A0A6I8PUD4_HUMAN,tr|A0A6I8PU73|A0A6I8PU73_HUMAN,tr|A0A6I8PU89|A0A6I8PU89_HUMAN" 10 1590.7559 0.64 100507 13180 2 1590.755687 796.3852 DnaJ homolog subfamily C member 7 OS=Homo sapiens OX=9606 GN=DNAJC7 PE=1 SV=2 4.23 2400.9 - 538319 - - - -0.1572 - 3.354 0.615 - 397.9 1 2 0 -0.0003 14 0 0 0 1.18E+07 1.84E+07 - - - 6.6201 1 221125_WJC_METTL3_EV_vs_WT_F07.13182.13182.3 3.36E-05 13/68 R.NLIATAQAQNQQQTEGVK.T sp|O94864|ST65G_HUMAN 1 1940.9916 1.33 100509 13182 3 1940.991921 648.0045 STAGA complex 65 subunit gamma OS=Homo sapiens OX=9606 GN=SUPT7L PE=1 SV=1 6 2401.1 - 971649 - - - 0.1819 - 2.698 0.479 - 147.5 1 2 0 0.0004 18 0 0 0 1.21E+07 9.09E+06 - - - 6.3517 0.9996 221125_WJC_METTL3_EV_vs_WT_F07.13187.13187.3 0.000451 Oct-44 R.RSDTSLTWNSVK.G "sp|P02788|TRFL_HUMAN,tr|E7EQB2|E7EQB2_HUMAN,tr|E7ER44|E7ER44_HUMAN" 3 1392.6997 19.59 100512 13187 3 1392.697352 465.2405 Lactotransferrin OS=Homo sapiens OX=9606 GN=LTF PE=1 SV=6 8.75 2401.7 - 1.04E+06 - - - -1.7168 - 1.81 0.371 - 100.2 1 2 0 -0.0024 12 0 0 0 1.18E+07 6.01E+05 - - - 4.3202 0.997 221125_WJC_METTL3_EV_vs_WT_F07.13188.13188.2 0.0409 20-Dec K.LK[136.11]VSELK[136.11]EELK[136.11].K "sp|Q00839|HNRPU_HUMAN,tr|A0A1W2PPS1|A0A1W2PPS1_HUMAN,tr|A0A1X7SBS1|A0A1X7SBS1_HUMAN" 3 1338.8185 0.86 100513 13188 2 1338.817702 670.4165 Heterogeneous nuclear ribonucleoprotein U OS=Homo sapiens OX=9606 GN=HNRNPU PE=1 SV=6 6.23 2401.9 - 736011 - - - -0.5721 - 1.957 0.393 - 325.1 1 2 2 -0.0008 11 0 0 0 1.43E+07 1.67E+07 - - - 3.7598 1 221125_WJC_METTL3_EV_vs_WT_F07.13192.13192.3 9.80E-07 15/72 K.VAPSWPESHSSADSASLAK.K sp|Q7LBC6|KDM3B_HUMAN 1 1925.9119 0.59 100515 13192 3 1925.909475 642.9779 Lysine-specific demethylase 3B OS=Homo sapiens OX=9606 GN=KDM3B PE=1 SV=2 5.32 2402.4 - 1.63E+06 - - - -1.2695 - 2.972 0.616 - 204.4 1 2 0 -0.0024 19 0 0 0 3.03E+07 5.15E+07 - - - 8.0831 1 221125_WJC_METTL3_EV_vs_WT_F07.13195.13195.2 9.40E-10 13/26 K.DNGNGTYSC[160.03]SYVPR[166.11].K "sp|P21333|FLNA_HUMAN,tr|A0A7P0NMY4|A0A7P0NMY4_HUMAN,tr|Q60FE5|Q60FE5_HUMAN" 3 1598.6659 1.06 100518 13195 2 1598.664191 800.3402 Filamin-A OS=Homo sapiens OX=9606 GN=FLNA PE=1 SV=4 5.83 2402.8 - 446449 - - - -1.0628 - 2.885 0.713 - 572.8 1 2 0 -0.0017 14 0 0 0 1.20E+07 1.13E+07 - - - 6.9655 0.9412 221125_WJC_METTL3_EV_vs_WT_F07.13203.13203.3 0.0168 13/60 K.TLPAHSDPVSAVHFNR[166.11].D sp|P61964|WDR5_HUMAN 1 1756.8884 1.33 100524 13203 3 1757.88299 586.6368 WD repeat-containing protein 5 OS=Homo sapiens OX=9606 GN=WDR5 PE=1 SV=1 6.61 2403.8 - 535984 - - - 566.0877 - 2.525 0.384 - 167.9 1 2 0 0.9946 16 0 0 0 2.87E+07 2.17E+07 - - - 4.9223 0.9922 221125_WJC_METTL3_EV_vs_WT_F07.13207.13207.2 0.000103 Aug-38 K.QSHAASAAPQASSPPDYTMA.W sp|Q96I24|FUBP3_HUMAN 1 1986.8742 - 100528 13207 2 1986.874336 994.4444 Far upstream element-binding protein 3 OS=Homo sapiens OX=9606 GN=FUBP3 PE=1 SV=2 5.08 2404.3 - 221478 - - - 0.0911 - 1.626 0.607 - 83.3 1 1 0 0.0002 20 0 0 0 - - - - - 4.7194 1 221125_WJC_METTL3_EV_vs_WT_F07.13210.13210.3 2.78E-05 18/48 R.EDPNLVPSISNKR.L sp|P10606|COX5B_HUMAN 1 1467.7682 0.6 100529 13210 3 1467.768528 490.2633 "Cytochrome c oxidase subunit 5B, mitochondrial OS=Homo sapiens OX=9606 GN=COX5B PE=1 SV=2" 6.17 2404.7 - 833179 - - - 0.2528 - 2.476 0.484 - 500.8 1 2 0 0.0004 13 0 0 0 3.40E+07 5.62E+07 - - - 6.3942 0.9997 221125_WJC_METTL3_EV_vs_WT_F07.13211.13211.3 0.0012 Nov-60 K.LQQAAQQHIQQQLLAK[136.11].Q sp|Q9UKJ3|GPTC8_HUMAN 1 1853.0363 0.76 100530 13211 3 1853.035585 618.686 G patch domain-containing protein 8 OS=Homo sapiens OX=9606 GN=GPATCH8 PE=1 SV=2 8.76 2404.8 - 923994 - - - -0.3751 - 1.921 0.366 - 142.4 1 2 0 -0.0007 16 0 0 0 1.31E+07 1.73E+07 - - - 4.2955 1 221125_WJC_METTL3_EV_vs_WT_F07.13213.13213.3 2.31E-06 17/60 K.TLPAHSDPVSAVHFNR.D sp|P61964|WDR5_HUMAN 1 1746.8802 1.35 100532 13213 3 1746.881972 583.3007 WD repeat-containing protein 5 OS=Homo sapiens OX=9606 GN=WDR5 PE=1 SV=1 6.61 2404.9 - 917768 - - - 1.0333 - 3.178 0.534 - 318.6 1 2 0 0.0018 16 0 0 0 2.91E+07 2.17E+07 - - - 7.4599 0.9749 221125_WJC_METTL3_EV_vs_WT_F07.13218.13218.3 7.18E-07 14/52 K.LKEENFFGPKEEVK.L sp|Q9NZI8|IF2B1_HUMAN 1 1692.8723 1.73 100536 13218 3 1692.873191 565.298 Insulin-like growth factor 2 mRNA-binding protein 1 OS=Homo sapiens OX=9606 GN=IGF2BP1 PE=1 SV=2 4.95 2405.5 - 2.93E+06 - - - 0.534 - 2.562 0.101 - 153.5 1 2 2 0.0009 14 0 0 0 1.40E+08 8.08E+07 - - - 2.166 0.9999 221125_WJC_METTL3_EV_vs_WT_F07.13222.13222.3 0.0016 17/44 K.ANKLDHVVTIIK.G "sp|Q99873|ANM1_HUMAN,tr|E9PQ98|E9PQ98_HUMAN,tr|E9PKG1|E9PKG1_HUMAN,tr|E9PNR9|E9PNR9_HUMAN,tr|H0YDE4|H0YDE4_HUMAN,tr|E9PIX6|E9PIX6_HUMAN" 6 1349.8031 2.05 100539 13222 3 1349.803418 450.9416 Protein arginine N-methyltransferase 1 OS=Homo sapiens OX=9606 GN=PRMT1 PE=1 SV=3 8.64 2406 - 1.36E+06 - - - 0.2467 - 3.592 0.488 - 374.7 1 2 1 0.0003 12 0 0 0 1.12E+08 5.46E+07 - - - 7.525 0.9997 221125_WJC_METTL3_EV_vs_WT_F07.13224.13224.3 3.21E-07 17/52 K.NKLNDLEDALQQAK.E sp|P04264|K2C1_HUMAN 1 1598.8264 2.49 100541 13224 3 1598.829265 533.9494 "Keratin, type II cytoskeletal 1 OS=Homo sapiens OX=9606 GN=KRT1 PE=1 SV=6" 4.56 2406.2 - 1.02E+06 - - - 1.7919 - 2.635 0.466 - 512.9 1 2 1 0.0029 14 0 0 0 1.57E+07 6.29E+06 - - - 6.3095 0.9747 221125_WJC_METTL3_EV_vs_WT_F07.13225.13225.4 0.23 13/96 K.LC[160.03]TDLEEKHEASEIQIK.Q sp|Q15643|TRIPB_HUMAN 1 2041.999 1.33 100542 13225 4 2042.000915 511.507 Thyroid receptor-interacting protein 11 OS=Homo sapiens OX=9606 GN=TRIP11 PE=1 SV=3 4.57 2406.3 - 909642 - - - 0.9275 - 2.405 0.206 - 149.8 1 2 1 0.0019 17 0 0 0 1.45E+07 1.09E+07 - - - 1.3232 1 221125_WJC_METTL3_EV_vs_WT_F07.13226.13226.2 1.82E-12 14/26 K.DNGNGTYSC[160.03]SYVPR.K "sp|P21333|FLNA_HUMAN,tr|A0A7P0NMY4|A0A7P0NMY4_HUMAN,tr|Q60FE5|Q60FE5_HUMAN" 3 1588.6576 1.06 100543 13226 2 1588.660459 795.3361 Filamin-A OS=Homo sapiens OX=9606 GN=FLNA PE=1 SV=4 5.83 2406.4 - 599197 - - - 1.787 - 2.665 0.777 - 663.8 1 2 0 0.0028 14 0 0 0 1.20E+07 1.13E+07 - - - 7.2388 0.9998 221125_WJC_METTL3_EV_vs_WT_F07.13227.13227.3 0.000183 13/48 R.EDPNLVPSISNK[136.11]R[166.11].L sp|P10606|COX5B_HUMAN 1 1485.7906 0.61 100544 13227 3 1485.787006 496.2708 "Cytochrome c oxidase subunit 5B, mitochondrial OS=Homo sapiens OX=9606 GN=COX5B PE=1 SV=2" 6.17 2406.5 - 488285 - - - -2.4371 - 2.144 0.445 - 215.1 1 2 0 -0.0036 13 0 0 0 3.45E+07 5.66E+07 - - - 5.5681 0.9999 221125_WJC_METTL3_EV_vs_WT_F07.13228.13228.3 2.21E-07 14/64 K.LC[160.03]TDLEEKHEASEIQIK.Q sp|Q15643|TRIPB_HUMAN 1 2041.999 1.32 100545 13228 3 2042.000592 681.6736 Thyroid receptor-interacting protein 11 OS=Homo sapiens OX=9606 GN=TRIP11 PE=1 SV=3 4.57 2406.6 - 422783 - - - 0.7693 - 2.939 0.54 - 227.6 1 2 1 0.0016 17 0 0 0 4.73E+06 3.59E+06 - - - 7.2836 0.9775 221125_WJC_METTL3_EV_vs_WT_F07.13233.13233.3 1.37 14/44 K.ESHRLPVDIAYK.R sp|P15924|DESP_HUMAN 1 1426.7569 15.7 100548 13233 3 1426.762665 476.5929 Desmoplakin OS=Homo sapiens OX=9606 GN=DSP PE=1 SV=3 6.85 2407.3 - 2.33E+06 - - - 4.0659 - 2.594 0.225 - 210 1 2 1 0.0058 12 0 0 0 1.28E+08 8.13E+06 - - - 3.6891 1 221125_WJC_METTL3_EV_vs_WT_F07.13234.13234.3 3.98E-09 20/68 K.VQEQVHTLLSQDQAQAAR[166.11].L sp|Q07065|CKAP4_HUMAN 1 2031.0373 1.66 100549 13234 3 2031.040798 678.0197 Cytoskeleton-associated protein 4 OS=Homo sapiens OX=9606 GN=CKAP4 PE=1 SV=2 5.32 2407.4 - 1.66E+06 - - - 1.7292 - 3.524 0.613 - 394.5 1 2 0 0.0035 18 0 0 0 9.12E+07 5.48E+07 - - - 8.5099 0.9943 221125_WJC_METTL3_EV_vs_WT_F07.13238.13238.2 0.00567 20-Nov K.LKVSELKEELK.K "sp|Q00839|HNRPU_HUMAN,tr|A0A1W2PPS1|A0A1W2PPS1_HUMAN,tr|A0A1X7SBS1|A0A1X7SBS1_HUMAN" 3 1314.7759 0.86 100553 13238 2 1314.777861 658.3952 Heterogeneous nuclear ribonucleoprotein U OS=Homo sapiens OX=9606 GN=HNRNPU PE=1 SV=6 6.23 2407.7 - 484730 - - - 1.5158 - 1.907 0.379 - 207.2 1 2 2 0.002 11 0 0 0 1.43E+07 1.67E+07 - - - 3.586 0.9008 221125_WJC_METTL3_EV_vs_WT_F07.13239.13239.4 1.94 Aug-96 R.TLPMSPPSERVQEQSAR[166.11].M sp|O15062|ZBTB5_HUMAN 1 1921.9555 - 100554 13239 4 1921.958953 481.4962 Zinc finger and BTB domain-containing protein 5 OS=Homo sapiens OX=9606 GN=ZBTB5 PE=1 SV=1 5.81 2407.8 - 461045 - - - 1.781 - 1.576 0.178 - 27 1 2 1 0.0034 17 0 0 0 - - - - - 0.9323 0.9996 221125_WJC_METTL3_EV_vs_WT_F07.13244.13244.3 0.00531 13/44 K.ANK[136.11]LDHVVTIIK[136.11].G "sp|Q99873|ANM1_HUMAN,tr|E9PQ98|E9PQ98_HUMAN,tr|E9PKG1|E9PKG1_HUMAN,tr|E9PNR9|E9PNR9_HUMAN,tr|H0YDE4|H0YDE4_HUMAN,tr|E9PIX6|E9PIX6_HUMAN" 6 1365.8315 2.05 100557 13244 3 1365.832736 456.2844 Protein arginine N-methyltransferase 1 OS=Homo sapiens OX=9606 GN=PRMT1 PE=1 SV=3 8.64 2408.4 - 1.17E+06 - - - 0.9159 - 1.904 0.459 - 164.3 1 2 1 0.0013 12 0 0 0 1.12E+08 5.46E+07 - - - 5.442 0.9993 221125_WJC_METTL3_EV_vs_WT_F07.13250.13250.3 0.00942 Sep-48 R.TDSTSDGRPAWMR.T "sp|Q14204|DYHC1_HUMAN,tr|A0A7P0T9C4|A0A7P0T9C4_HUMAN,tr|A0A2R8Y706|A0A2R8Y706_HUMAN,tr|A0A7P0TAW9|A0A7P0TAW9_HUMAN,tr|A0A7P0TA13|A0A7P0TA13_HUMAN,tr|A0A7P0T7V5|A0A7P0T7V5_HUMAN,tr|A0A7P0T9R4|A0A7P0T9R4_HUMAN,tr|A0A2R8Y5T0|A0A2R8Y5T0_HUMAN" 8 1478.6572 1.38 100563 13250 3 1478.658172 493.893 Cytoplasmic dynein 1 heavy chain 1 OS=Homo sapiens OX=9606 GN=DYNC1H1 PE=1 SV=5 5.63 2409 - 515383 - - - 0.6398 - 1.639 0.327 - 116 1 2 0 0.0009 13 0 0 0 5.77E+06 4.19E+06 - - - 3.5251 0.9963 221125_WJC_METTL3_EV_vs_WT_F07.13258.13258.3 0.305 Jun-72 K.EPGDQGPAHPPGADMSHSL.- sp|Q9Y399|RT02_HUMAN 1 1898.8217 - 100569 13258 3 1898.82254 633.9479 "28S ribosomal protein S2, mitochondrial OS=Homo sapiens OX=9606 GN=MRPS2 PE=1 SV=1" 4.52 2409.8 - 910022 - - - 0.4292 - 1.216 0.306 - 26.8 1 2 0 0.0008 19 0 0 0 - - - - - 2.4318 1 221125_WJC_METTL3_EV_vs_WT_F07.13263.13263.3 7.13E-10 22/64 K.DVGR[166.11]PNFEEGGPTSVGR[166.11].K "sp|Q6Y7W6|GGYF2_HUMAN,tr|E7ESB6|E7ESB6_HUMAN" 2 1792.8607 3.19 100572 13263 3 1792.861306 598.6275 GRB10-interacting GYF protein 2 OS=Homo sapiens OX=9606 GN=GIGYF2 PE=1 SV=1 4.68 2410.5 - 1.61E+06 - - - 0.3296 - 4.116 0.642 - 592.2 1 2 0 0.0006 17 0 0 0 4.73E+08 1.48E+08 - - - 9.2719 0.9934 221125_WJC_METTL3_EV_vs_WT_F07.13264.13264.3 0.0394 Nov-44 R.YDGVHFSVNDSK[136.11].Y "sp|O15047|SET1A_HUMAN,tr|A0A804HLA6|A0A804HLA6_HUMAN,tr|C9J2Z9|C9J2Z9_HUMAN" 3 1374.6295 1.18 100573 13264 3 1374.628994 459.2171 Histone-lysine N-methyltransferase SETD1A OS=Homo sapiens OX=9606 GN=SETD1A PE=1 SV=3 5.21 2410.7 - 434739 - - - -0.4001 - 1.217 0.267 - 88.5 1 2 0 -0.0006 12 0 0 0 7.66E+06 6.49E+06 - - - 2.061 0.9996 221125_WJC_METTL3_EV_vs_WT_F07.13265.13265.4 0.00255 16/126 R.LASEAKPAAVAAENEEIGSHIK.H sp|Q9Y490|TLN1_HUMAN 1 2234.1543 1.13 100574 13265 4 2234.15958 559.5458 Talin-1 OS=Homo sapiens OX=9606 GN=TLN1 PE=1 SV=3 4.91 2410.8 - 633834 - - - 2.3741 - 3.125 0.376 - 138.6 1 2 0 0.0053 22 0 0 0 2.38E+07 2.11E+07 - - - 2.8701 0.9999 221125_WJC_METTL3_EV_vs_WT_F07.13267.13267.3 5.79E-05 13/72 K.VNPFRPGDSEPPPAPGAQR.A "sp|Q15942|ZYX_HUMAN,tr|H0Y2Y8|H0Y2Y8_HUMAN,tr|C9IZ41|C9IZ41_HUMAN" 3 1987.9864 2.41 100576 13267 3 1987.986825 663.6694 Zyxin OS=Homo sapiens OX=9606 GN=ZYX PE=1 SV=1 6.04 2411 - 285663 - - - 0.2022 - 2.709 0.434 - 215.5 1 2 0 0.0004 19 0 0 0 2.70E+07 1.12E+07 - - - 5.827 0.9999 221125_WJC_METTL3_EV_vs_WT_F07.13271.13271.4 3.38E-05 16/90 K.TLPAHSDPVSAVHFNR.D sp|P61964|WDR5_HUMAN 1 1746.8802 1.53 100578 13271 4 1746.881321 437.7273 WD repeat-containing protein 5 OS=Homo sapiens OX=9606 GN=WDR5 PE=1 SV=1 6.61 2411.5 - 3.57E+06 - - - 0.6606 - 2.302 0.447 - 151.8 1 2 0 0.0012 16 0 0 0 6.88E+07 4.49E+07 - - - 3.4101 1 221125_WJC_METTL3_EV_vs_WT_F07.13273.13273.3 1.96E-08 19/64 K.DVGRPNFEEGGPTSVGR.K "sp|Q6Y7W6|GGYF2_HUMAN,tr|E7ESB6|E7ESB6_HUMAN" 2 1772.8442 3.19 100580 13273 3 1772.848175 591.9553 GRB10-interacting GYF protein 2 OS=Homo sapiens OX=9606 GN=GIGYF2 PE=1 SV=1 4.68 2411.6 - 5.88E+06 - - - 2.2563 - 3.974 0.569 - 385.9 1 2 0 0.004 17 0 0 0 4.73E+08 1.48E+08 - - - 8.3684 0.9665 221125_WJC_METTL3_EV_vs_WT_F07.13279.13279.4 0.0254 Aug-90 R.LSHLKPSSEGLAIVTK.Y sp|P10155|RO60_HUMAN 1 1678.9618 0.67 100586 13279 4 1678.960663 420.7477 60 kDa SS-A\Ro ribonucleoprotein OS=Homo sapiens OX=9606 GN=RO60 PE=1 SV=2 8.6 2412.3 - 271458 - - - -0.6599 - 1.896 0.176 - 64.3 2 2 0 -0.0011 16 0 0 0 3.41E+06 5.11E+06 - - - 0.7535 1 221125_WJC_METTL3_EV_vs_WT_F07.13285.13285.3 1.01E-06 13/44 K.YNIWC[160.03]STEHGNK.R sp|Q9Y5A9|YTHD2_HUMAN 1 1507.6514 1.4 100590 13285 3 1507.651882 503.5577 YTH domain-containing family protein 2 OS=Homo sapiens OX=9606 GN=YTHDF2 PE=1 SV=2 6.74 2413.1 - 722977 - - - 0.3117 - 2.198 0.539 - 155.9 1 2 0 0.0005 12 0 0 0 9.53E+07 6.79E+07 - - - 6.7322 0.9992 221125_WJC_METTL3_EV_vs_WT_F07.13286.13286.2 1.22E-05 Oct-32 K.DVGRPNFEEGGPTSVGR.K "sp|Q6Y7W6|GGYF2_HUMAN,tr|E7ESB6|E7ESB6_HUMAN" 2 1772.8442 39.01 100591 13286 2 1772.849594 887.4294 GRB10-interacting GYF protein 2 OS=Homo sapiens OX=9606 GN=GIGYF2 PE=1 SV=1 4.68 2413.2 - 410520 - - - 3.0567 - 2.042 0.487 - 57.7 1 2 0 0.0054 17 0 0 0 1.95E+07 5.00E+05 - - - 4.3915 0.9916 221125_WJC_METTL3_EV_vs_WT_F07.13287.13287.2 0.000523 22-Nov K.ESHRLPVDIAYK.R sp|P15924|DESP_HUMAN 1 1426.7569 999 100592 13287 2 1426.755699 714.3857 Desmoplakin OS=Homo sapiens OX=9606 GN=DSP PE=1 SV=3 6.85 2413.3 - 352984 - - - -0.8165 - 2.197 0.219 - 404 1 2 1 -0.0012 12 0 0 0 4.01E+06 0.00E+00 - - - 2.7291 0.9988 221125_WJC_METTL3_EV_vs_WT_F07.13292.13292.3 0.00963 13/44 K.ESHR[166.11]LPVDIAYK[136.11].R sp|P15924|DESP_HUMAN 1 1444.7793 15.7 100596 13292 3 1444.779593 482.6004 Desmoplakin OS=Homo sapiens OX=9606 GN=DSP PE=1 SV=3 6.85 2413.9 - 573359 - - - 0.1793 - 2.146 0.33 - 156.9 1 2 1 0.0003 12 0 0 0 1.28E+08 8.13E+06 - - - 4.3357 1 221125_WJC_METTL3_EV_vs_WT_F07.13294.13294.4 1.24E-05 21/126 R.LASEAK[136.11]PAAVAAENEEIGSHIK[136.11].H sp|Q9Y490|TLN1_HUMAN 1 2250.1827 1.13 100597 13294 4 2250.183929 563.5529 Talin-1 OS=Homo sapiens OX=9606 GN=TLN1 PE=1 SV=3 4.91 2414.1 - 1.49E+06 - - - 0.5568 - 3.666 0.506 - 304.2 1 2 0 0.0013 22 0 0 0 2.38E+07 2.11E+07 - - - 4.0549 1 221125_WJC_METTL3_EV_vs_WT_F07.13295.13295.3 7.26E-07 15/64 R.EAEETQSTLQAEC[160.03]DQYR.S "sp|Q9P2E9|RRBP1_HUMAN,tr|A0A087WU26|A0A087WU26_HUMAN,tr|A0A087WVV2|A0A087WVV2_HUMAN,tr|F8W7S5|F8W7S5_HUMAN" 4 2056.8644 0.77 100598 13295 3 2056.865995 686.6287 Ribosome-binding protein 1 OS=Homo sapiens OX=9606 GN=RRBP1 PE=1 SV=5 3.91 2414.3 - 797377 - - - 0.7861 - 2.914 0.593 - 293.9 1 2 0 0.0016 17 0 0 0 8.53E+06 1.11E+07 - - - 7.8529 1 221125_WJC_METTL3_EV_vs_WT_F07.13298.13298.3 8.07E-07 15/44 K.YNIWC[160.03]STEHGNK[136.11].R sp|Q9Y5A9|YTHD2_HUMAN 1 1515.6656 1.42 100601 13298 3 1515.665367 506.2291 YTH domain-containing family protein 2 OS=Homo sapiens OX=9606 GN=YTHDF2 PE=1 SV=2 6.74 2414.5 - 1.28E+06 - - - -0.1616 - 2.54 0.539 - 222.9 1 2 0 -0.0002 12 0 0 0 9.58E+07 6.74E+07 - - - 7.1331 1 221125_WJC_METTL3_EV_vs_WT_F07.13304.13304.2 6.43E-07 Dec-32 R.EAEETQSTLQAEC[160.03]DQYR.S "sp|Q9P2E9|RRBP1_HUMAN,tr|A0A087WU26|A0A087WU26_HUMAN,tr|A0A087WVV2|A0A087WVV2_HUMAN,tr|F8W7S5|F8W7S5_HUMAN" 4 2056.8644 1.05 100607 13304 2 2056.86613 1029.4395 Ribosome-binding protein 1 OS=Homo sapiens OX=9606 GN=RRBP1 PE=1 SV=5 3.91 2415.3 - 296231 - - - 0.8518 - 3.087 0.615 - 404.4 1 2 0 0.0018 17 0 0 0 4.43E+06 4.20E+06 - - - 6.3541 1 221125_WJC_METTL3_EV_vs_WT_F07.13308.13308.3 7.31E-08 20/68 K.VQEQVHTLLSQDQAQAAR.L sp|Q07065|CKAP4_HUMAN 1 2021.029 1.69 100610 13308 3 2021.029231 674.6836 Cytoskeleton-associated protein 4 OS=Homo sapiens OX=9606 GN=CKAP4 PE=1 SV=2 5.32 2415.8 - 2.52E+06 - - - 0.1064 - 3.644 0.609 - 438.7 1 2 0 0.0002 18 0 0 0 9.26E+07 5.48E+07 - - - 8.5496 0.9998 221125_WJC_METTL3_EV_vs_WT_F07.13310.13310.2 0.0195 13/22 R.ALEESNYELEGK.L "sp|P13645|K1C10_HUMAN,tr|A0A1B0GVI3|A0A1B0GVI3_HUMAN" 2 1380.6409 999 100611 13310 2 1380.639577 691.3277 "Keratin, type I cytoskeletal 10 OS=Homo sapiens OX=9606 GN=KRT10 PE=1 SV=6" 4.09 2416 - 1.98E+06 - - - -0.951 - 2.5 0.408 - 508.7 1 2 0 -0.0013 12 0 0 0 2.70E+07 0.00E+00 - - - 4.465 1 221125_WJC_METTL3_EV_vs_WT_F07.13312.13312.2 6.84E-08 17/32 R.TDYNASVSVPDSSGPER.L "sp|P61978|HNRPK_HUMAN,tr|Q5T6W2|Q5T6W2_HUMAN" 2 1779.7911 1.39 100613 13312 2 1779.791107 890.9028 Heterogeneous nuclear ribonucleoprotein K OS=Homo sapiens OX=9606 GN=HNRNPK PE=1 SV=1 4.03 2416.2 - 2.29E+06 - - - -0.0163 - 3.173 0.687 - 653 1 2 0 0 17 0 0 0 1.56E+09 1.12E+09 - - - 6.954 1 221125_WJC_METTL3_EV_vs_WT_F07.13314.13314.2 2.95E-09 18/32 R.TDYNASVSVPDSSGPER[166.11].L "sp|P61978|HNRPK_HUMAN,tr|Q5T6W2|Q5T6W2_HUMAN" 2 1789.7994 1.39 100615 13314 2 1789.79652 895.907 Heterogeneous nuclear ribonucleoprotein K OS=Homo sapiens OX=9606 GN=HNRNPK PE=1 SV=1 4.03 2416.4 - 2.00E+06 - - - -1.6125 - 3.391 0.636 - 815.7 1 2 0 -0.0029 17 0 0 0 1.55E+09 1.12E+09 - - - 6.7398 0.9999 221125_WJC_METTL3_EV_vs_WT_F07.13315.13315.3 7.15E-05 14/52 R.EQLQDLHDQIAGQK[136.11].A sp|Q8TBA6|GOGA5_HUMAN 1 1629.8202 1.7 100616 13315 3 1629.820716 544.2807 Golgin subfamily A member 5 OS=Homo sapiens OX=9606 GN=GOLGA5 PE=1 SV=3 4.54 2416.4 - 1.85E+06 - - - 0.3172 - 2.998 0.382 - 211.7 1 2 0 0.0005 14 0 0 0 9.23E+07 5.44E+07 - - - 5.7166 1 221125_WJC_METTL3_EV_vs_WT_F07.13320.13320.2 1.89E-13 16/36 R.SSLGQSASETEEDTVSVSK.K "sp|Q13435|SF3B2_HUMAN,tr|E9PPJ0|E9PPJ0_HUMAN,tr|H0YCG1|H0YCG1_HUMAN,tr|E9PJ04|E9PJ04_HUMAN" 4 1939.8858 1.54 100621 13320 2 1939.887624 970.9502 Splicing factor 3B subunit 2 OS=Homo sapiens OX=9606 GN=SF3B2 PE=1 SV=2 4 2417 - 319000 - - - 0.9274 - 3.385 0.667 - 730.8 1 2 0 0.0018 19 0 0 0 1.06E+07 6.87E+06 - - - 6.9647 1 221125_WJC_METTL3_EV_vs_WT_F07.13323.13323.3 6.97E-05 Dec-64 R.TDYNASVSVPDSSGPER.L "sp|P61978|HNRPK_HUMAN,tr|Q5T6W2|Q5T6W2_HUMAN" 2 1779.7911 1.55 100622 13323 3 1779.789872 594.271 Heterogeneous nuclear ribonucleoprotein K OS=Homo sapiens OX=9606 GN=HNRNPK PE=1 SV=1 4.03 2417.4 - 1.57E+06 - - - -0.7102 - 2.217 0.532 - 159.3 1 2 0 -0.0013 17 0 0 0 4.04E+08 2.61E+08 - - - 6.4822 0.9744 221125_WJC_METTL3_EV_vs_WT_F07.13325.13325.4 0.175 17/90 R.VLDGPEKVPVVHVDEK.G sp|Q8TEM1|PO210_HUMAN 1 1758.9516 2.86 100624 13325 4 1758.950163 440.7452 Nuclear pore membrane glycoprotein 210 OS=Homo sapiens OX=9606 GN=NUP210 PE=1 SV=3 4.75 2417.6 - 921734 - - - -0.817 - 2.074 0.211 - 122.8 1 2 1 -0.0014 16 0 0 0 4.56E+07 1.59E+07 - - - 1.3191 0.9999 221125_WJC_METTL3_EV_vs_WT_F07.13327.13327.3 1.49E-05 16/36 K.R[166.11]LHVSNIPFR[166.11].F "sp|O43251|RFOX2_HUMAN,sp|Q9NWB1|RFOX1_HUMAN,sp|A6NFN3|RFOX3_HUMAN,tr|A0A6Q8PGE0|A0A6Q8PGE0_HUMAN,tr|A0A6Q8PH77|A0A6Q8PH77_HUMAN,tr|A0A286YEU2|A0A286YEU2_HUMAN,tr|A0A087X2B1|A0A087X2B1_HUMAN,tr|F8VR27|F8VR27_HUMAN,tr|B7Z1U7|B7Z1U7_HUMAN,tr|B0QYY6|B0QYY6_HUMAN,tr|B0QYV1|B0QYV1_HUMAN,tr|A0A6Q8PHA3|A0A6Q8PHA3_HUMAN,tr|A0A3B3ITL7|A0A3B3ITL7_HUMAN,tr|F8VZY7|F8VZY7_HUMAN,tr|B0QYY4|B0QYY4_HUMAN,tr|J3KNW3|J3KNW3_HUMAN,tr|F8VZG9|F8VZG9_HUMAN,tr|J3QRF4|J3QRF4_HUMAN,tr|F8VRS4|F8VRS4_HUMAN,tr|A0A6Q8PFM4|A0A6Q8PFM4_HUMAN,tr|S4R469|S4R469_HUMAN,tr|A0A804HKG7|A0A804HKG7_HUMAN,tr|A0A0G2JRA5|A0A0G2JRA5_HUMAN,tr|A0A804HJM2|A0A804HJM2_HUMAN,tr|J3QQZ2|J3QQZ2_HUMAN,tr|I3L1D4|I3L1D4_HUMAN,tr|B0QYY7|B0QYY7_HUMAN,tr|A0A0G2JSB3|A0A0G2JSB3_HUMAN" 28 1257.7209 1.14 100626 13327 3 1257.72139 420.2476 RNA binding protein fox-1 homolog 2 OS=Homo sapiens OX=9606 GN=RBFOX2 PE=1 SV=3 12 2417.8 - 495956 - - - 0.3785 - 3.452 0.318 - 623.7 1 2 0 0.0005 10 0 0 0 5.38E+08 4.73E+08 - - - 5.7035 1 221125_WJC_METTL3_EV_vs_WT_F07.13328.13328.2 1.30E-10 19/36 R.SSLGQSASETEEDTVSVSK[136.11].K "sp|Q13435|SF3B2_HUMAN,tr|E9PPJ0|E9PPJ0_HUMAN,tr|H0YCG1|H0YCG1_HUMAN,tr|E9PJ04|E9PJ04_HUMAN" 4 1947.9 1.54 100627 13328 2 1947.898969 974.9573 Splicing factor 3B subunit 2 OS=Homo sapiens OX=9606 GN=SF3B2 PE=1 SV=2 4 2418 - 485532 - - - -0.5421 - 3.691 0.745 - 1076.6 1 2 0 -0.0011 19 0 0 0 1.06E+07 6.87E+06 - - - 7.7538 1 221125_WJC_METTL3_EV_vs_WT_F07.13329.13329.2 6.45E-10 14/28 K.MEEFK[136.11]DQLPADEC[160.03]NK[136.11].L "sp|P38646|GRP75_HUMAN,tr|A0A7I2V2S7|A0A7I2V2S7_HUMAN,tr|A0A7I2V2G2|A0A7I2V2G2_HUMAN,tr|A0A7I2V3F7|A0A7I2V3F7_HUMAN,tr|A0A7I2YQB2|A0A7I2YQB2_HUMAN,tr|D6RCD7|D6RCD7_HUMAN" 6 1868.8256 0.33 100628 13329 2 1868.823782 935.4201 "Stress-70 protein, mitochondrial OS=Homo sapiens OX=9606 GN=HSPA9 PE=1 SV=2" 4.18 2418.1 - 470548 - - - -0.946 - 2.88 0.694 - 506.5 1 2 1 -0.0018 15 0 0 0 6.07E+06 1.83E+07 - - - 6.767 1 221125_WJC_METTL3_EV_vs_WT_F07.13333.13333.3 3.53E-10 19/44 K.KAVLFC[160.03]LSEDKK.N "sp|P23528|COF1_HUMAN,tr|E9PP50|E9PP50_HUMAN,tr|G3V1A4|G3V1A4_HUMAN,tr|E9PQB7|E9PQB7_HUMAN,tr|E9PK25|E9PK25_HUMAN,tr|E9PLJ3|E9PLJ3_HUMAN,tr|E9PS23|E9PS23_HUMAN" 7 1436.7697 1.54 100630 13333 3 1436.767393 479.9305 Cofilin-1 OS=Homo sapiens OX=9606 GN=CFL1 PE=1 SV=3 8.18 2418.6 - 2.41E+06 - - - -1.6314 - 3.025 0.622 - 715.5 1 2 0 -0.0023 12 0 0 0 1.21E+08 7.84E+07 - - - 8.5422 1 221125_WJC_METTL3_EV_vs_WT_F07.13334.13334.3 4.09E-06 15/48 R.SIFQHIQSAQSQR.S "sp|Q9Y2W1|TR150_HUMAN,tr|A0A3B3ITZ9|A0A3B3ITZ9_HUMAN" 2 1528.7746 2.58 100631 13334 3 1528.772696 510.5988 Thyroid hormone receptor-associated protein 3 OS=Homo sapiens OX=9606 GN=THRAP3 PE=1 SV=2 9.49 2418.7 - 2.47E+06 - - - -1.271 - 2.385 0.501 - 203.9 1 2 0 -0.0019 13 0 0 0 4.88E+10 1.89E+10 - - - 6.4818 0.9986 221125_WJC_METTL3_EV_vs_WT_F07.13335.13335.3 1.37E-06 16/52 D.R[166.11]FSGSGSGTDFTLK.L "sp|A2NJV5|KV229_HUMAN,sp|A0A087WW87|KV240_HUMAN,sp|P06310|KV230_HUMAN,sp|A0A075B6S2|KVD29_HUMAN,sp|P01614|KVD40_HUMAN,sp|P01615|KVD28_HUMAN,sp|A0A075B6S6|KVD30_HUMAN,sp|A0A075B6P5|KV228_HUMAN,sp|A0A0A0MRZ7|KVD26_HUMAN" 9 1468.7186 - 100632 13335 3 1468.717659 490.5801 Immunoglobulin kappa variable 2-29 OS=Homo sapiens OX=9606 GN=IGKV2-29 PE=3 SV=2 8.75 2418.8 - 1.02E+06 - - - -0.625 - 3.455 0.525 - 444.8 1 1 0 -0.0009 14 0 0 0 - - - - - 7.6878 1 221125_WJC_METTL3_EV_vs_WT_F07.13338.13338.2 1.66E-07 15/34 K.LSETISEGTSNSLSTC[160.03]TK.S "sp|O75179|ANR17_HUMAN,tr|H0YM23|H0YM23_HUMAN" 2 1913.8888 5.07 100635 13338 2 1913.88516 957.9517 Ankyrin repeat domain-containing protein 17 OS=Homo sapiens OX=9606 GN=ANKRD17 PE=1 SV=3 4.53 2419.2 - 578146 - - - -1.9029 - 3.267 0.689 - 677.7 1 2 0 -0.0036 18 0 0 0 1.92E+07 3.78E+06 - - - 7.0394 0.9999 221125_WJC_METTL3_EV_vs_WT_F07.13342.13342.3 9.39E-05 13/48 R.SIFQHIQSAQSQR[166.11].S "sp|Q9Y2W1|TR150_HUMAN,tr|A0A3B3ITZ9|A0A3B3ITZ9_HUMAN" 2 1538.7829 2.58 100637 13342 3 1538.78084 513.9349 Thyroid hormone receptor-associated protein 3 OS=Homo sapiens OX=9606 GN=THRAP3 PE=1 SV=2 9.49 2419.6 - 4.00E+06 - - - -1.3446 - 2.009 0.457 - 161.5 1 2 0 -0.0021 13 0 0 0 4.85E+10 1.88E+10 - - - 5.526 1 221125_WJC_METTL3_EV_vs_WT_F07.13345.13345.2 9.44E-10 17/24 R.SIFQHIQSAQSQR.S "sp|Q9Y2W1|TR150_HUMAN,tr|A0A3B3ITZ9|A0A3B3ITZ9_HUMAN" 2 1528.7746 2.51 100640 13345 2 1528.773447 765.3946 Thyroid hormone receptor-associated protein 3 OS=Homo sapiens OX=9606 GN=THRAP3 PE=1 SV=2 9.49 2419.9 - 1.03E+06 - - - -0.7797 - 3.173 0.632 - 1268.9 1 2 0 -0.0012 13 0 0 0 8.93E+09 3.56E+09 - - - 6.6721 1 221125_WJC_METTL3_EV_vs_WT_F07.13347.13347.2 2.24E-11 15/36 R.SSLGQSASETEEDTVSVSK.K "sp|Q13435|SF3B2_HUMAN,tr|E9PPJ0|E9PPJ0_HUMAN,tr|H0YCG1|H0YCG1_HUMAN,tr|E9PJ04|E9PJ04_HUMAN" 4 1939.8858 1.54 100642 13347 2 1939.884756 970.9502 Splicing factor 3B subunit 2 OS=Homo sapiens OX=9606 GN=SF3B2 PE=1 SV=2 4 2420.2 - 812213 - - - -0.5511 - 3.401 0.661 - 642.2 1 2 0 -0.0011 19 0 0 0 1.06E+07 6.87E+06 - - - 6.9322 1 221125_WJC_METTL3_EV_vs_WT_F07.13352.13352.3 0.000266 14/64 R.TDYNASVSVPDSSGPER[166.11].L "sp|P61978|HNRPK_HUMAN,tr|Q5T6W2|Q5T6W2_HUMAN" 2 1789.7994 1.55 100645 13352 3 1789.79818 597.6071 Heterogeneous nuclear ribonucleoprotein K OS=Homo sapiens OX=9606 GN=HNRNPK PE=1 SV=1 4.03 2420.8 - 9.51E+06 - - - -0.685 - 2.724 0.529 - 223.6 1 2 0 -0.0012 17 0 0 0 4.04E+08 2.61E+08 - - - 6.9691 1 221125_WJC_METTL3_EV_vs_WT_F07.13353.13353.2 0.00195 16/24 R.SIFQHIQSAQSQR[166.11].S "sp|Q9Y2W1|TR150_HUMAN,tr|A0A3B3ITZ9|A0A3B3ITZ9_HUMAN" 2 1538.7829 2.51 100646 13353 2 1538.781269 770.3987 Thyroid hormone receptor-associated protein 3 OS=Homo sapiens OX=9606 GN=THRAP3 PE=1 SV=2 9.49 2420.9 - 2.09E+06 - - - -1.0658 - 3.12 0.554 - 1101.7 1 2 0 -0.0016 13 0 0 0 8.93E+09 3.56E+09 - - - 6.0526 1 221125_WJC_METTL3_EV_vs_WT_F07.13354.13354.3 2.84E-05 17/44 K.K[136.11]AVLFC[160.03]LSEDK[136.11]K[136.11].N "sp|P23528|COF1_HUMAN,tr|E9PP50|E9PP50_HUMAN,tr|G3V1A4|G3V1A4_HUMAN,tr|E9PQB7|E9PQB7_HUMAN,tr|E9PK25|E9PK25_HUMAN,tr|E9PLJ3|E9PLJ3_HUMAN,tr|E9PS23|E9PS23_HUMAN" 7 1460.8123 1.54 100647 13354 3 1460.811194 487.9447 Cofilin-1 OS=Homo sapiens OX=9606 GN=CFL1 PE=1 SV=3 8.18 2420.9 - 4.09E+06 - - - -0.7824 - 2.921 0.6 - 517.4 1 2 0 -0.0011 12 0 0 0 1.21E+08 7.84E+07 - - - 8.2003 1 221125_WJC_METTL3_EV_vs_WT_F07.13355.13355.3 8.61E-07 16/64 K.AAYLQETGKPLDETLKK.A "sp|P04083|ANXA1_HUMAN,tr|Q5T3N1|Q5T3N1_HUMAN,tr|Q5T3N0|Q5T3N0_HUMAN" 3 1904.0255 999 100648 13355 3 1904.026162 635.6824 Annexin A1 OS=Homo sapiens OX=9606 GN=ANXA1 PE=1 SV=2 6.22 2421 - 948650 - - - 0.3508 - 2.704 0.471 - 177.9 1 2 0 0.0007 17 0 0 0 3.23E+07 0.00E+00 - - - 6.304 0.9863 221125_WJC_METTL3_EV_vs_WT_F07.13357.13357.2 4.02E-07 13/20 L.FQHIQSAQSQR.S "sp|Q9Y2W1|TR150_HUMAN,tr|A0A3B3ITZ9|A0A3B3ITZ9_HUMAN" 2 1328.6585 2.49 100650 13357 2 1328.656977 665.3365 Thyroid hormone receptor-associated protein 3 OS=Homo sapiens OX=9606 GN=THRAP3 PE=1 SV=2 9.76 2421.3 - 817100 - - - -1.1809 - 2.091 0.435 - 734.6 1 1 0 -0.0016 11 0 0 0 1.73E+09 6.94E+08 - - - 4.2489 0.9998 221125_WJC_METTL3_EV_vs_WT_F07.13363.13363.3 1.59E-06 Nov-56 K.MEEFKDQLPADEC[160.03]NK.L "sp|P38646|GRP75_HUMAN,tr|A0A7I2V2S7|A0A7I2V2S7_HUMAN,tr|A0A7I2V2G2|A0A7I2V2G2_HUMAN,tr|A0A7I2V3F7|A0A7I2V3F7_HUMAN,tr|A0A7I2YQB2|A0A7I2YQB2_HUMAN,tr|D6RCD7|D6RCD7_HUMAN" 6 1852.7972 0.41 100654 13363 3 1852.794759 618.6063 "Stress-70 protein, mitochondrial OS=Homo sapiens OX=9606 GN=HSPA9 PE=1 SV=2" 4.18 2422 - 9.51E+06 - - - -1.2905 - 2.354 0.519 - 163.8 1 2 1 -0.0024 15 0 0 0 1.68E+08 4.08E+08 - - - 6.5596 1 221125_WJC_METTL3_EV_vs_WT_F07.13368.13368.3 2.06E-08 18/72 R.TAGPLESSETEEASQLKER.L "sp|Q9P2E9|RRBP1_HUMAN,tr|A0A087WU26|A0A087WU26_HUMAN,tr|A0A087WVV2|A0A087WVV2_HUMAN,tr|F8W7S5|F8W7S5_HUMAN" 4 2060.9862 1.28 100659 13368 3 2060.987069 688.0027 Ribosome-binding protein 1 OS=Homo sapiens OX=9606 GN=RRBP1 PE=1 SV=5 4.32 2422.6 - 486127 - - - 0.4178 - 3.768 0.568 - 204.6 1 2 1 0.0009 19 0 0 0 2.16E+07 1.69E+07 - - - 8.1315 0.9998 221125_WJC_METTL3_EV_vs_WT_F07.13369.13369.2 1.80E-05 Jul-32 R.NTNSVPETAPAAIPETK.R "sp|P55265|DSRAD_HUMAN,tr|A0A3B3ITG9|A0A3B3ITG9_HUMAN,tr|A0A3B3IRQ9|A0A3B3IRQ9_HUMAN,tr|A0A3B3ISU1|A0A3B3ISU1_HUMAN,tr|A0A7P0Z4K3|A0A7P0Z4K3_HUMAN,tr|A0A7P0TA14|A0A7P0TA14_HUMAN,tr|A0A3B3ISX1|A0A3B3ISX1_HUMAN,tr|A0A7P0Z4F9|A0A7P0Z4F9_HUMAN" 8 1738.8737 1.14 100660 13369 2 1738.872987 870.4441 Double-stranded RNA-specific adenosine deaminase OS=Homo sapiens OX=9606 GN=ADAR PE=1 SV=4 4.53 2422.7 - 481283 - - - -0.4353 - 1.569 0.52 - 127.1 1 2 0 -0.0008 17 0 0 0 6.24E+07 5.45E+07 - - - 3.9889 0.9844 221125_WJC_METTL3_EV_vs_WT_F07.13373.13373.2 0.00245 14/20 L.FQHIQSAQSQR[166.11].S "sp|Q9Y2W1|TR150_HUMAN,tr|A0A3B3ITZ9|A0A3B3ITZ9_HUMAN" 2 1338.6668 2.49 100662 13373 2 1338.664555 670.3407 Thyroid hormone receptor-associated protein 3 OS=Homo sapiens OX=9606 GN=THRAP3 PE=1 SV=2 9.76 2423.2 - 2.95E+06 - - - -1.689 - 2.116 0.463 - 835.8 1 1 0 -0.0023 11 0 0 0 1.73E+09 6.93E+08 - - - 4.4877 0.9999 221125_WJC_METTL3_EV_vs_WT_F07.13375.13375.3 0.00229 Dec-52 R.EQLQDLHDQIAGQK.A sp|Q8TBA6|GOGA5_HUMAN 1 1621.806 1.69 100664 13375 3 1621.805761 541.6093 Golgin subfamily A member 5 OS=Homo sapiens OX=9606 GN=GOLGA5 PE=1 SV=3 4.54 2423.4 - 2.31E+06 - - - -0.1467 - 2.508 0.42 - 173.3 1 2 0 -0.0002 14 0 0 0 9.23E+07 5.45E+07 - - - 5.6661 0.9999 221125_WJC_METTL3_EV_vs_WT_F07.13380.13380.3 0.0325 16/36 K.RLHVSNIPFR.F "sp|O43251|RFOX2_HUMAN,sp|Q9NWB1|RFOX1_HUMAN,sp|A6NFN3|RFOX3_HUMAN,tr|A0A6Q8PGE0|A0A6Q8PGE0_HUMAN,tr|A0A6Q8PH77|A0A6Q8PH77_HUMAN,tr|A0A286YEU2|A0A286YEU2_HUMAN,tr|A0A087X2B1|A0A087X2B1_HUMAN,tr|F8VR27|F8VR27_HUMAN,tr|B7Z1U7|B7Z1U7_HUMAN,tr|B0QYY6|B0QYY6_HUMAN,tr|B0QYV1|B0QYV1_HUMAN,tr|A0A6Q8PHA3|A0A6Q8PHA3_HUMAN,tr|A0A3B3ITL7|A0A3B3ITL7_HUMAN,tr|F8VZY7|F8VZY7_HUMAN,tr|B0QYY4|B0QYY4_HUMAN,tr|J3KNW3|J3KNW3_HUMAN,tr|F8VZG9|F8VZG9_HUMAN,tr|J3QRF4|J3QRF4_HUMAN,tr|F8VRS4|F8VRS4_HUMAN,tr|A0A6Q8PFM4|A0A6Q8PFM4_HUMAN,tr|S4R469|S4R469_HUMAN,tr|A0A804HKG7|A0A804HKG7_HUMAN,tr|A0A0G2JRA5|A0A0G2JRA5_HUMAN,tr|A0A804HJM2|A0A804HJM2_HUMAN,tr|J3QQZ2|J3QQZ2_HUMAN,tr|I3L1D4|I3L1D4_HUMAN,tr|B0QYY7|B0QYY7_HUMAN,tr|A0A0G2JSB3|A0A0G2JSB3_HUMAN" 28 1237.7044 1.14 100667 13380 3 1237.701671 413.5754 RNA binding protein fox-1 homolog 2 OS=Homo sapiens OX=9606 GN=RBFOX2 PE=1 SV=3 12 2424.1 - 6.66E+06 - - - -2.1839 - 2.848 0.432 - 592 1 2 0 -0.0027 10 0 0 0 5.38E+08 4.73E+08 - - - 6.4122 0.9999 221125_WJC_METTL3_EV_vs_WT_F07.13387.13387.2 5.88E-06 Oct-32 R.NTNSVPETAPAAIPETK[136.11].R "sp|P55265|DSRAD_HUMAN,tr|A0A3B3ITG9|A0A3B3ITG9_HUMAN,tr|A0A3B3IRQ9|A0A3B3IRQ9_HUMAN,tr|A0A3B3ISU1|A0A3B3ISU1_HUMAN,tr|A0A7P0Z4K3|A0A7P0Z4K3_HUMAN,tr|A0A7P0TA14|A0A7P0TA14_HUMAN,tr|A0A3B3ISX1|A0A3B3ISX1_HUMAN,tr|A0A7P0Z4F9|A0A7P0Z4F9_HUMAN" 8 1746.8879 1.14 100672 13387 2 1746.886076 874.4512 Double-stranded RNA-specific adenosine deaminase OS=Homo sapiens OX=9606 GN=ADAR PE=1 SV=4 4.53 2424.9 - 1.08E+06 - - - -1.0693 - 1.999 0.634 - 196.8 1 2 0 -0.0019 17 0 0 0 6.24E+07 5.45E+07 - - - 5.426 0.9999 221125_WJC_METTL3_EV_vs_WT_F07.13398.13398.3 5.99E-06 13/56 K.MEEFK[136.11]DQLPADEC[160.03]NK[136.11].L "sp|P38646|GRP75_HUMAN,tr|A0A7I2V2S7|A0A7I2V2S7_HUMAN,tr|A0A7I2V2G2|A0A7I2V2G2_HUMAN,tr|A0A7I2V3F7|A0A7I2V3F7_HUMAN,tr|A0A7I2YQB2|A0A7I2YQB2_HUMAN,tr|D6RCD7|D6RCD7_HUMAN" 6 1868.8256 0.41 100678 13398 3 1868.821511 623.9491 "Stress-70 protein, mitochondrial OS=Homo sapiens OX=9606 GN=HSPA9 PE=1 SV=2" 4.18 2426.3 - 5.82E+06 - - - -2.1613 - 2.626 0.594 - 216.4 1 2 1 -0.004 15 0 0 0 1.68E+08 4.08E+08 - - - 7.6806 0.9882 221125_WJC_METTL3_EV_vs_WT_F07.13399.13399.3 0.129 14/68 R.C[160.03]QAAEPQIITGSHDTTIR.L "sp|O43660|PLRG1_HUMAN,tr|H0YA24|H0YA24_HUMAN" 2 1996.9636 1.32 100679 13399 3 1996.966799 666.6618 Pleiotropic regulator 1 OS=Homo sapiens OX=9606 GN=PLRG1 PE=1 SV=1 5.32 2426.3 - 1.87E+07 - - - 1.5824 - 1.551 0.208 - 86.8 1 2 0 0.0032 18 0 0 0 1.02E+08 7.68E+07 - - - 1.951 0.9656 221125_WJC_METTL3_EV_vs_WT_F07.13417.13417.2 0.000118 15/18 F.QHIQSAQSQR.S "sp|Q9Y2W1|TR150_HUMAN,tr|A0A3B3ITZ9|A0A3B3ITZ9_HUMAN" 2 1181.5901 2.9 100692 13417 2 1181.586379 591.8023 Thyroid hormone receptor-associated protein 3 OS=Homo sapiens OX=9606 GN=THRAP3 PE=1 SV=2 9.76 2428.3 - 2.97E+06 - - - -3.1762 - 2.253 0.49 - 651.4 1 1 0 -0.0038 10 0 0 0 1.39E+08 4.82E+07 - - - 4.9262 0.9923 221125_WJC_METTL3_EV_vs_WT_F07.13418.13418.3 3.98E-06 16/40 L.FQHIQSAQSQR.S "sp|Q9Y2W1|TR150_HUMAN,tr|A0A3B3ITZ9|A0A3B3ITZ9_HUMAN" 2 1328.6585 2.52 100693 13418 3 1328.655324 443.8935 Thyroid hormone receptor-associated protein 3 OS=Homo sapiens OX=9606 GN=THRAP3 PE=1 SV=2 9.76 2428.4 - 1.59E+06 - - - -2.425 - 2.562 0.475 - 363.1 1 1 0 -0.0032 11 0 0 0 3.99E+07 1.58E+07 - - - 6.5075 1 221125_WJC_METTL3_EV_vs_WT_F07.13425.13425.3 1.77E-08 17/72 K.QNLEGDHSDAPMETETSFK[136.11].N "sp|O95757|HS74L_HUMAN,tr|D6RJ96|D6RJ96_HUMAN,tr|E9PDE8|E9PDE8_HUMAN" 3 2142.9255 0.04 100698 13425 3 2142.919662 715.3158 Heat shock 70 kDa protein 4L OS=Homo sapiens OX=9606 GN=HSPA4L PE=1 SV=3 4.17 2429.3 - 1.80E+06 - - - -2.7374 - 3.367 0.595 - 370 1 2 0 -0.0059 19 0 0 0 1.94E+06 5.24E+07 - - - 8.1546 0.9401 221125_WJC_METTL3_EV_vs_WT_F07.13434.13434.3 0.0112 14/60 K.EK[136.11]LPGELEPVQATQNK[136.11].T "sp|O75821|EIF3G_HUMAN,tr|K7ER90|K7ER90_HUMAN,tr|K7EL20|K7EL20_HUMAN,tr|K7EP16|K7EP16_HUMAN" 4 1795.9651 1.22 100702 13434 3 1795.960097 599.6623 Eukaryotic translation initiation factor 3 subunit G OS=Homo sapiens OX=9606 GN=EIF3G PE=1 SV=2 4.79 2430.5 - 1.41E+06 - - - -2.774 - 1.717 0.215 - 48.5 1 2 1 -0.005 16 0 0 0 1.19E+08 9.76E+07 - - - 2.3227 0.9997 221125_WJC_METTL3_EV_vs_WT_F07.13446.13446.3 5.57E-06 17/60 K.EKLPGELEPVQATQNK.T "sp|O75821|EIF3G_HUMAN,tr|K7ER90|K7ER90_HUMAN,tr|K7EL20|K7EL20_HUMAN,tr|K7EP16|K7EP16_HUMAN" 4 1779.9367 1.22 100709 13446 3 1779.940962 594.3195 Eukaryotic translation initiation factor 3 subunit G OS=Homo sapiens OX=9606 GN=EIF3G PE=1 SV=2 4.79 2431.9 - 2.03E+06 - - - 2.4063 - 3.069 0.461 - 493.4 1 2 1 0.0043 16 0 0 0 1.19E+08 9.76E+07 - - - 6.5557 0.9705 221125_WJC_METTL3_EV_vs_WT_F07.13447.13447.2 0.00145 18-Nov F.QHIQSAQSQR[166.11].S "sp|Q9Y2W1|TR150_HUMAN,tr|A0A3B3ITZ9|A0A3B3ITZ9_HUMAN" 2 1191.5984 2.9 100710 13447 2 1191.595616 596.8065 Thyroid hormone receptor-associated protein 3 OS=Homo sapiens OX=9606 GN=THRAP3 PE=1 SV=2 9.76 2432 - 1.05E+06 - - - -2.338 - 1.821 0.472 - 426.9 1 1 0 -0.0028 10 0 0 0 1.39E+08 4.82E+07 - - - 4.1994 0.9999 221125_WJC_METTL3_EV_vs_WT_F07.13451.13451.3 0.000298 13/48 R.K[136.11]ASGPPVSELITK[136.11].A "sp|P10412|H14_HUMAN,sp|P16403|H12_HUMAN,sp|P16402|H13_HUMAN" 3 1341.7839 1.14 100712 13451 3 1341.780007 448.2686 Histone H1.4 OS=Homo sapiens OX=9606 GN=H1-4 PE=1 SV=2 8.59 2432.6 - 879086 - - - -2.8768 - 2.686 0.516 - 273.4 1 2 0 -0.0039 13 0 0 0 3.26E+07 2.87E+07 - - - 6.9707 0.9996 221125_WJC_METTL3_EV_vs_WT_F07.13456.13456.3 3.69E-06 15/52 R.HQSFVLVGETGSGK[136.11].T sp|O43143|DHX15_HUMAN 1 1452.7452 0.91 100715 13456 3 1452.743704 485.2557 Pre-mRNA-splicing factor ATP-dependent RNA helicase DHX15 OS=Homo sapiens OX=9606 GN=DHX15 PE=1 SV=2 6.75 2433.2 - 1.62E+06 - - - -1.0594 - 2.572 0.266 - 419.2 1 2 0 -0.0015 14 0 0 0 1.16E+08 1.27E+08 - - - 4.0157 0.999 221125_WJC_METTL3_EV_vs_WT_F07.13457.13457.3 1.29E-05 14/56 K.INEKPQVIADYESGR.A sp|O60869|EDF1_HUMAN 1 1717.8635 0.61 100716 13457 3 1717.864196 573.6284 Endothelial differentiation-related factor 1 OS=Homo sapiens OX=9606 GN=EDF1 PE=1 SV=1 4.68 2433.3 - 669058 - - - 0.397 - 2.036 0.259 - 189.8 1 2 0 0.0007 15 0 0 0 1.77E+07 2.90E+07 - - - 3.2826 0.9999 221125_WJC_METTL3_EV_vs_WT_F07.13458.13458.3 1.51E-09 20/56 K.INEK[136.11]PQVIADYESGR[166.11].A sp|O60869|EDF1_HUMAN 1 1735.886 0.6 100717 13458 3 1735.881414 579.6359 Endothelial differentiation-related factor 1 OS=Homo sapiens OX=9606 GN=EDF1 PE=1 SV=1 4.68 2433.5 - 1.52E+06 - - - -2.6327 - 3.268 0.425 - 544.5 1 2 0 -0.0046 15 0 0 0 1.75E+07 2.90E+07 - - - 6.367 1 221125_WJC_METTL3_EV_vs_WT_F07.13459.13459.2 1.36E-15 19/34 Y.GNQPSSYGAQAASSYGVR.A sp|Q96PK6|RBM14_HUMAN 1 1798.8234 2.76 100718 13459 2 1798.819473 900.419 RNA-binding protein 14 OS=Homo sapiens OX=9606 GN=RBM14 PE=1 SV=2 8.59 2433.6 - 801686 - - - -2.2053 - 3.832 0.732 - 1188.2 1 1 0 -0.004 18 0 0 0 2.02E+07 7.33E+06 - - - 7.7491 1 221125_WJC_METTL3_EV_vs_WT_F07.13462.13462.3 7.81E-12 20/60 K.SSEHINEGETAMLVC[160.03]K.S "sp|P35613|BASI_HUMAN,tr|A0A7P0T8A7|A0A7P0T8A7_HUMAN,tr|A0A087WUV8|A0A087WUV8_HUMAN,tr|A0A7P0TA85|A0A7P0TA85_HUMAN,tr|A0A7P0TB04|A0A7P0TB04_HUMAN,tr|R4GMX5|R4GMX5_HUMAN,tr|R4GN83|R4GN83_HUMAN,tr|I3L192|I3L192_HUMAN" 8 1803.8131 0.86 100719 13462 3 1803.810905 602.2783 Basigin OS=Homo sapiens OX=9606 GN=BSG PE=1 SV=2 4.75 2434 - 2.16E+06 - - - -1.2363 - 3.781 0.661 - 580.6 1 2 0 -0.0022 16 0 0 0 1.89E+08 2.18E+08 - - - 9.3214 0.9999 221125_WJC_METTL3_EV_vs_WT_F07.13464.13464.3 0.000153 21/60 R.TK[136.11]AEEPSDLIGPEAPK[136.11].T "sp|Q8N5F7|NKAP_HUMAN,tr|A0A494C050|A0A494C050_HUMAN" 2 1696.8854 0.94 100720 13464 3 1696.884664 566.6358 NF-kappa-B-activating protein OS=Homo sapiens OX=9606 GN=NKAP PE=1 SV=1 4.41 2434.2 - 2.11E+06 - - - -0.452 - 3.366 0.478 - 578.3 1 2 1 -0.0008 16 0 0 0 6.38E+07 6.82E+07 - - - 6.9833 0.9992 221125_WJC_METTL3_EV_vs_WT_F07.13467.13467.3 0.000163 13/48 R.NDKDKPLPPLLAR.V "sp|Q14839|CHD4_HUMAN,tr|A0A2R8Y4X2|A0A2R8Y4X2_HUMAN,tr|A0A2U3TZM0|A0A2U3TZM0_HUMAN,tr|A0A2R8Y5M9|A0A2R8Y5M9_HUMAN,tr|A0A2R8Y445|A0A2R8Y445_HUMAN,tr|A0A2R8YD40|A0A2R8YD40_HUMAN,tr|A0A2R8Y5J0|A0A2R8Y5J0_HUMAN,tr|A0A2R8Y425|A0A2R8Y425_HUMAN,tr|A0A2R8YFK9|A0A2R8YFK9_HUMAN,tr|A0A2R8Y8C1|A0A2R8Y8C1_HUMAN,tr|A0A0C4DGG9|A0A0C4DGG9_HUMAN,tr|A0A2R8YFD8|A0A2R8YFD8_HUMAN,tr|A0A2R8YDW2|A0A2R8YDW2_HUMAN,tr|A0A2R8Y7I0|A0A2R8Y7I0_HUMAN,tr|F5GWX5|F5GWX5_HUMAN,tr|A0A2R8YER1|A0A2R8YER1_HUMAN,tr|A0A2R8Y7M9|A0A2R8Y7M9_HUMAN,tr|A0A2R8Y521|A0A2R8Y521_HUMAN,tr|A0A2R8YDJ9|A0A2R8YDJ9_HUMAN,tr|A0A2R8Y212|A0A2R8Y212_HUMAN,tr|A0A2R8YE38|A0A2R8YE38_HUMAN" 21 1475.846 1.31 100722 13467 3 1475.843482 492.9559 Chromodomain-helicase-DNA-binding protein 4 OS=Homo sapiens OX=9606 GN=CHD4 PE=1 SV=2 8.59 2434.5 - 1.23E+06 - - - -1.7149 - 2.5 0.362 - 228.2 1 2 1 -0.0025 13 0 0 0 3.98E+07 3.04E+07 - - - 5.0596 1 221125_WJC_METTL3_EV_vs_WT_F07.13471.13471.3 1.44E-07 15/44 K.QQHVIETLIGK[136.11]K[136.11].Q "sp|P48643|TCPE_HUMAN,tr|E9PCA1|E9PCA1_HUMAN,tr|B7ZAR1|B7ZAR1_HUMAN,tr|E7ENZ3|E7ENZ3_HUMAN" 4 1408.8373 0.63 100724 13471 3 1408.8362 470.6197 T-complex protein 1 subunit epsilon OS=Homo sapiens OX=9606 GN=CCT5 PE=1 SV=1 8.6 2435 - 2.70E+06 - - - -0.7801 - 2.423 0.584 - 356.6 1 2 0 -0.0011 12 0 0 0 1.68E+08 2.67E+08 - - - 7.5038 0.9998 221125_WJC_METTL3_EV_vs_WT_F07.13472.13472.3 1.50E-07 18/60 R.TKAEEPSDLIGPEAPK.T "sp|Q8N5F7|NKAP_HUMAN,tr|A0A494C050|A0A494C050_HUMAN" 2 1680.857 0.94 100725 13472 3 1680.852864 561.293 NF-kappa-B-activating protein OS=Homo sapiens OX=9606 GN=NKAP PE=1 SV=1 4.41 2435.1 - 2.22E+06 - - - -2.4791 - 3.231 0.557 - 398.4 1 2 1 -0.0042 16 0 0 0 6.38E+07 6.82E+07 - - - 7.7581 0.9995 221125_WJC_METTL3_EV_vs_WT_F07.13473.13473.3 0.000424 15/52 K.VSGQEDFSHQLYQR[166.11].K "sp|Q9UNK9|ANGE1_HUMAN,tr|G3V414|G3V414_HUMAN" 2 1702.7939 0.11 100726 13473 3 1702.799537 568.6052 Protein angel homolog 1 OS=Homo sapiens OX=9606 GN=ANGEL1 PE=1 SV=1 5.32 2435.2 - 1.34E+06 - - - 3.3292 - 2.653 0.356 - 290 1 2 0 0.0057 14 0 0 0 2.19E+06 2.03E+07 - - - 5.1004 0.9996 221125_WJC_METTL3_EV_vs_WT_F07.13474.13474.3 3.83E-08 16/72 K.VDATR[166.11]PEATTEVGPQIGVK[136.11].E sp|Q96T58|MINT_HUMAN 1 1985.0548 1.76 100727 13474 3 1985.043349 662.6922 Msx2-interacting protein OS=Homo sapiens OX=9606 GN=SPEN PE=1 SV=1 4.68 2435.3 - 1.02E+06 - - - -5.7888 - 3.266 0.544 - 268.5 1 2 0 -0.0115 19 0 0 0 4.61E+07 2.62E+07 - - - 7.5097 1 221125_WJC_METTL3_EV_vs_WT_F07.13478.13478.3 1.43E-07 15/52 R.HQSFVLVGETGSGK.T sp|O43143|DHX15_HUMAN 1 1444.731 0.92 100729 13478 3 1444.729212 482.5843 Pre-mRNA-splicing factor ATP-dependent RNA helicase DHX15 OS=Homo sapiens OX=9606 GN=DHX15 PE=1 SV=2 6.75 2435.8 - 3.47E+06 - - - -1.2674 - 2.827 0.596 - 443.1 1 2 0 -0.0018 14 0 0 0 1.15E+08 1.25E+08 - - - 7.9461 1 221125_WJC_METTL3_EV_vs_WT_F07.13480.13480.3 1.54E-10 17/56 K.AVDQHNAEAQDIFGK.N "sp|P52732|KIF11_HUMAN,tr|A0A7I2YQY4|A0A7I2YQY4_HUMAN,tr|A0A7I2V3A9|A0A7I2V3A9_HUMAN" 3 1641.7747 5.01 100731 13480 3 1641.774169 548.2655 Kinesin-like protein KIF11 OS=Homo sapiens OX=9606 GN=KIF11 PE=1 SV=2 4.54 2436 - 3.43E+06 - - - -0.3222 - 3.448 0.6 - 293.5 1 2 0 -0.0005 15 0 0 0 1.64E+09 3.28E+08 - - - 8.4591 1 221125_WJC_METTL3_EV_vs_WT_F07.13481.13481.3 0.00139 18/44 K.QQHVIETLIGKK.Q "sp|P48643|TCPE_HUMAN,tr|E9PCA1|E9PCA1_HUMAN,tr|B7ZAR1|B7ZAR1_HUMAN,tr|E7ENZ3|E7ENZ3_HUMAN" 4 1392.8089 0.63 100732 13481 3 1392.807873 465.2769 T-complex protein 1 subunit epsilon OS=Homo sapiens OX=9606 GN=CCT5 PE=1 SV=1 8.6 2436.2 - 1.86E+06 - - - -0.7366 - 2.765 0.461 - 419.4 1 2 0 -0.001 12 0 0 0 1.68E+08 2.67E+08 - - - 6.4985 1 221125_WJC_METTL3_EV_vs_WT_F07.13482.13482.3 5.94E-09 24/72 K.VDATRPEATTEVGPQIGVK.E sp|Q96T58|MINT_HUMAN 1 1967.0324 1.76 100733 13482 3 1967.032705 656.6847 Msx2-interacting protein OS=Homo sapiens OX=9606 GN=SPEN PE=1 SV=1 4.68 2436.3 - 1.40E+06 - - - 0.1703 - 3.208 0.529 - 569.5 1 2 0 0.0003 19 0 0 0 4.61E+07 2.62E+07 - - - 7.3015 0.9999 221125_WJC_METTL3_EV_vs_WT_F07.13485.13485.3 3.99E-06 14/48 R.NREEEWDPEYTPK.S "sp|Q9Y2W1|TR150_HUMAN,tr|A0A3B3ITZ9|A0A3B3ITZ9_HUMAN" 2 1691.7427 2.98 100734 13485 3 1691.740485 564.9215 Thyroid hormone receptor-associated protein 3 OS=Homo sapiens OX=9606 GN=THRAP3 PE=1 SV=2 4.25 2436.7 - 2.00E+06 - - - -1.327 - 2.722 0.547 - 364.5 1 2 1 -0.0022 13 0 0 0 2.42E+10 8.14E+09 - - - 7.3529 0.9971 221125_WJC_METTL3_EV_vs_WT_F07.13486.13486.3 0.117 Dec-56 K.QASIQHIQNAIDTEK[136.11].S "sp|P24539|AT5F1_HUMAN,tr|Q5QNZ2|Q5QNZ2_HUMAN" 2 1702.873 1.28 100735 13486 3 1702.872222 568.6316 "ATP synthase F(0) complex subunit B1, mitochondrial OS=Homo sapiens OX=9606 GN=ATP5PB PE=1 SV=2" 5.32 2436.7 - 1.73E+06 - - - -0.4351 - 2.253 0.172 - 210.2 1 2 0 -0.0007 15 0 0 0 5.43E+07 4.25E+07 - - - 2.5769 1 221125_WJC_METTL3_EV_vs_WT_F07.13487.13487.3 2.77E-10 17/56 K.AVDQHNAEAQDIFGK[136.11].N "sp|P52732|KIF11_HUMAN,tr|A0A7I2YQY4|A0A7I2YQY4_HUMAN,tr|A0A7I2V3A9|A0A7I2V3A9_HUMAN" 3 1649.7889 5.01 100736 13487 3 1649.794561 550.9369 Kinesin-like protein KIF11 OS=Homo sapiens OX=9606 GN=KIF11 PE=1 SV=2 4.54 2436.9 - 1.66E+06 - - - 3.4326 - 3.327 0.626 - 249.9 1 2 0 0.0057 15 0 0 0 1.64E+09 3.28E+08 - - - 8.6544 0.9996 221125_WJC_METTL3_EV_vs_WT_F07.13488.13488.3 4.07E-05 16/48 R.NDK[136.11]DK[136.11]PLPPLLAR[166.11].V "sp|Q14839|CHD4_HUMAN,tr|A0A2R8Y4X2|A0A2R8Y4X2_HUMAN,tr|A0A2U3TZM0|A0A2U3TZM0_HUMAN,tr|A0A2R8Y5M9|A0A2R8Y5M9_HUMAN,tr|A0A2R8Y445|A0A2R8Y445_HUMAN,tr|A0A2R8YD40|A0A2R8YD40_HUMAN,tr|A0A2R8Y5J0|A0A2R8Y5J0_HUMAN,tr|A0A2R8Y425|A0A2R8Y425_HUMAN,tr|A0A2R8YFK9|A0A2R8YFK9_HUMAN,tr|A0A2R8Y8C1|A0A2R8Y8C1_HUMAN,tr|A0A0C4DGG9|A0A0C4DGG9_HUMAN,tr|A0A2R8YFD8|A0A2R8YFD8_HUMAN,tr|A0A2R8YDW2|A0A2R8YDW2_HUMAN,tr|A0A2R8Y7I0|A0A2R8Y7I0_HUMAN,tr|F5GWX5|F5GWX5_HUMAN,tr|A0A2R8YER1|A0A2R8YER1_HUMAN,tr|A0A2R8Y7M9|A0A2R8Y7M9_HUMAN,tr|A0A2R8Y521|A0A2R8Y521_HUMAN,tr|A0A2R8YDJ9|A0A2R8YDJ9_HUMAN,tr|A0A2R8Y212|A0A2R8Y212_HUMAN,tr|A0A2R8YE38|A0A2R8YE38_HUMAN" 21 1501.8827 1.52 100737 13488 3 1501.886302 501.6348 Chromodomain-helicase-DNA-binding protein 4 OS=Homo sapiens OX=9606 GN=CHD4 PE=1 SV=2 8.59 2437 - 909512 - - - 2.4096 - 2.345 0.496 - 349.7 1 2 1 0.0036 13 0 0 0 7.07E+07 4.64E+07 - - - 6.3797 0.941 221125_WJC_METTL3_EV_vs_WT_F07.13489.13489.3 0.929 Oct-44 K.QLLLQEVENHK[136.11]K[136.11].Q sp|Q12981|SEC20_HUMAN 1 1493.8537 0.92 100738 13489 3 1493.849124 498.9585 Vesicle transport protein SEC20 OS=Homo sapiens OX=9606 GN=BNIP1 PE=1 SV=3 6.76 2437.1 - 868776 - - - -3.0478 - 1.532 0.162 - 109.5 1 2 0 -0.0046 12 0 0 0 6.96E+06 7.54E+06 - - - 1.5273 0.9999 221125_WJC_METTL3_EV_vs_WT_F07.13495.13495.3 2.32E-08 15/48 R.NR[166.11]EEEWDPEYTPK[136.11].S "sp|Q9Y2W1|TR150_HUMAN,tr|A0A3B3ITZ9|A0A3B3ITZ9_HUMAN" 2 1709.7652 2.98 100740 13495 3 1709.761333 570.929 Thyroid hormone receptor-associated protein 3 OS=Homo sapiens OX=9606 GN=THRAP3 PE=1 SV=2 4.25 2437.9 - 2.54E+06 - - - -2.2617 - 2.712 0.596 - 420.3 1 2 1 -0.0039 13 0 0 0 2.42E+10 8.14E+09 - - - 7.8888 0.9976 221125_WJC_METTL3_EV_vs_WT_F07.13500.13500.3 0.0166 Dec-36 R.K[136.11]R[166.11]EEIPLDFK[136.11].T "sp|Q99549|MPP8_HUMAN,tr|A0A0A0MT47|A0A0A0MT47_HUMAN" 2 1299.7397 0.52 100745 13500 3 1299.737327 434.2538 M-phase phosphoprotein 8 OS=Homo sapiens OX=9606 GN=MPHOSPH8 PE=1 SV=2 6.18 2438.5 - 580990 - - - -1.8311 - 2.261 0.29 - 282.2 1 2 1 -0.0024 10 0 0 0 6.51E+06 1.26E+07 - - - 4.1551 1 221125_WJC_METTL3_EV_vs_WT_F07.13503.13503.3 9.16E-07 14/56 K.KAEAGAGSATEFQFR.G "sp|Q9NQ39|RS10L_HUMAN,sp|P46783|RS10_HUMAN" 2 1568.7583 1.24 100746 13503 3 1568.758841 523.9267 Putative 40S ribosomal protein S10-like OS=Homo sapiens OX=9606 GN=RPS10P5 PE=5 SV=1 6.14 2438.9 - 2.74E+06 - - - 0.3321 - 2.695 0.479 - 318.6 1 2 0 0.0005 15 0 0 0 7.74E+09 6.24E+09 - - - 6.4672 1 221125_WJC_METTL3_EV_vs_WT_F07.13504.13504.4 1.39E-05 22/96 R.YLQAHTQSVYNYHLSPR.A sp|P50548|ERF_HUMAN 1 2076.0177 1.82 100747 13504 4 2076.015596 520.0117 ETS domain-containing transcription factor ERF OS=Homo sapiens OX=9606 GN=ERF PE=1 SV=2 8.51 2439 - 1.69E+06 - - - -1.0246 - 3.725 0.505 - 407.3 1 2 0 -0.0021 17 0 0 0 2.94E+07 1.62E+07 - - - 4.0775 1 221125_WJC_METTL3_EV_vs_WT_F07.13505.13505.3 9.32E-14 21/72 K.TEELNREVATNSELVQSGK.S "sp|Q04695|K1C17_HUMAN,sp|P02533|K1C14_HUMAN,tr|K7ESE1|K7ESE1_HUMAN,tr|F5GWP8|F5GWP8_HUMAN" 4 2103.0444 999 100748 13505 3 2103.045581 702.0221 "Keratin, type I cytoskeletal 17 OS=Homo sapiens OX=9606 GN=KRT17 PE=1 SV=2" 4.49 2439.2 - 2.23E+06 - - - 0.5658 - 4.535 0.645 - 529.5 1 2 1 0.0012 19 0 0 0 1.87E+08 0.00E+00 - - - 9.445 1 221125_WJC_METTL3_EV_vs_WT_F07.13507.13507.2 2.56E-09 19/28 K.AVDQHNAEAQDIFGK.N "sp|P52732|KIF11_HUMAN,tr|A0A7I2YQY4|A0A7I2YQY4_HUMAN,tr|A0A7I2V3A9|A0A7I2V3A9_HUMAN" 3 1641.7747 5.82 100750 13507 2 1641.774348 821.8946 Kinesin-like protein KIF11 OS=Homo sapiens OX=9606 GN=KIF11 PE=1 SV=2 4.54 2439.4 - 1.38E+06 - - - -0.2132 - 4.118 0.668 - 1332.5 1 2 0 -0.0003 15 0 0 0 1.31E+08 2.25E+07 - - - 7.4545 1 221125_WJC_METTL3_EV_vs_WT_F07.13514.13514.2 2.05E-09 16/24 R.NREEEWDPEYTPK.S "sp|Q9Y2W1|TR150_HUMAN,tr|A0A3B3ITZ9|A0A3B3ITZ9_HUMAN" 2 1691.7427 2.96 100755 13514 2 1691.742269 846.8786 Thyroid hormone receptor-associated protein 3 OS=Homo sapiens OX=9606 GN=THRAP3 PE=1 SV=2 4.25 2440.4 - 2.14E+06 - - - -0.2725 - 3.013 0.696 - 720.3 1 2 1 -0.0005 13 0 0 0 3.46E+09 1.17E+09 - - - 7.0122 1 221125_WJC_METTL3_EV_vs_WT_F07.13515.13515.2 2.79E-11 14/24 R.NR[166.11]EEEWDPEYTPK[136.11].S "sp|Q9Y2W1|TR150_HUMAN,tr|A0A3B3ITZ9|A0A3B3ITZ9_HUMAN" 2 1709.7652 2.96 100756 13515 2 1709.764301 855.8899 Thyroid hormone receptor-associated protein 3 OS=Homo sapiens OX=9606 GN=THRAP3 PE=1 SV=2 4.25 2440.6 - 970868 - - - -0.5258 - 2.835 0.711 - 517.3 1 2 1 -0.0009 13 0 0 0 3.46E+09 1.17E+09 - - - 6.9666 0.9996 221125_WJC_METTL3_EV_vs_WT_F07.13516.13516.4 6.27E-05 Dec-84 K.FLQEHGSDSFLAEHK[136.11].L sp|Q00688|FKBP3_HUMAN 1 1751.8358 0.11 100757 13516 4 1751.834151 438.9662 Peptidyl-prolyl cis-trans isomerase FKBP3 OS=Homo sapiens OX=9606 GN=FKBP3 PE=1 SV=1 5.27 2440.7 - 1.60E+06 - - - -0.9693 - 1.933 0.35 - 118.5 1 2 0 -0.0017 15 0 0 0 1.26E+07 1.10E+08 - - - 2.5078 1 221125_WJC_METTL3_EV_vs_WT_F07.13519.13519.2 5.68E-10 23/28 K.K[136.11]AEAGAGSATEFQFR[166.11].G "sp|Q9NQ39|RS10L_HUMAN,sp|P46783|RS10_HUMAN" 2 1586.7808 1.25 100760 13519 2 1586.775634 794.3977 Putative 40S ribosomal protein S10-like OS=Homo sapiens OX=9606 GN=RPS10P5 PE=5 SV=1 6.14 2441.1 - 814232 - - - -3.2493 - 4.491 0.643 - 1921.5 1 2 0 -0.0052 15 0 0 0 8.63E+08 6.88E+08 - - - 7.4815 1 221125_WJC_METTL3_EV_vs_WT_F07.13524.13524.3 6.24E-06 17/56 K.K[136.11]AEAGAGSATEFQFR[166.11].G "sp|Q9NQ39|RS10L_HUMAN,sp|P46783|RS10_HUMAN" 2 1586.7808 1.24 100763 13524 3 1586.777986 529.9342 Putative 40S ribosomal protein S10-like OS=Homo sapiens OX=9606 GN=RPS10P5 PE=5 SV=1 6.14 2441.6 - 3.08E+07 - - - -1.7671 - 2.869 0.572 - 426.5 1 2 0 -0.0028 15 0 0 0 7.74E+09 6.24E+09 - - - 7.6666 1 221125_WJC_METTL3_EV_vs_WT_F07.13526.13526.2 3.98E-10 22/28 K.KAEAGAGSATEFQFR.G "sp|Q9NQ39|RS10L_HUMAN,sp|P46783|RS10_HUMAN" 2 1568.7583 1.25 100765 13526 2 1568.755827 785.3864 Putative 40S ribosomal protein S10-like OS=Homo sapiens OX=9606 GN=RPS10P5 PE=5 SV=1 6.14 2441.8 - 2.10E+06 - - - -1.5892 - 4.423 0.569 - 1649.3 1 2 0 -0.0025 15 0 0 0 8.63E+08 6.88E+08 - - - 6.8983 1 221125_WJC_METTL3_EV_vs_WT_F07.13528.13528.3 1.20E-06 17/52 K.NAC[160.03]DHLSGFNVC[160.03]NR[166.11].Y sp|Q9Y3B4|SF3B6_HUMAN 1 1672.7074 1.26 100767 13528 3 1672.70923 558.5764 Splicing factor 3B subunit 6 OS=Homo sapiens OX=9606 GN=SF3B6 PE=1 SV=1 6.73 2442 - 1.15E+06 - - - 1.1072 - 2.444 0.49 - 269.5 1 2 0 0.0019 14 0 0 0 1.66E+08 1.32E+08 - - - 6.3774 1 221125_WJC_METTL3_EV_vs_WT_F07.13531.13531.2 3.07E-10 19/28 K.AVDQHNAEAQDIFGK[136.11].N "sp|P52732|KIF11_HUMAN,tr|A0A7I2YQY4|A0A7I2YQY4_HUMAN,tr|A0A7I2V3A9|A0A7I2V3A9_HUMAN" 3 1649.7889 5.82 100770 13531 2 1650.785499 825.9017 Kinesin-like protein KIF11 OS=Homo sapiens OX=9606 GN=KIF11 PE=1 SV=2 4.54 2442.4 - 955826 - - - 604.0779 - 3.063 0.687 - 539.2 1 2 0 0.9966 15 0 0 0 1.31E+08 2.25E+07 - - - 6.5543 1 221125_WJC_METTL3_EV_vs_WT_F07.13532.13532.2 1.06E-09 19/24 V.DQHNAEAQDIFGK.N "sp|P52732|KIF11_HUMAN,tr|A0A7I2YQY4|A0A7I2YQY4_HUMAN,tr|A0A7I2V3A9|A0A7I2V3A9_HUMAN" 3 1471.6692 43.03 100771 13532 2 1471.669178 736.8419 Kinesin-like protein KIF11 OS=Homo sapiens OX=9606 GN=KIF11 PE=1 SV=2 4.54 2442.5 - 718453 - - - 0.0048 - 3.593 0.658 - 821.2 1 1 0 0 13 0 0 0 9.32E+06 2.17E+05 - - - 7.1835 1 221125_WJC_METTL3_EV_vs_WT_F07.13533.13533.3 9.51E-07 14/44 K.K[136.11]QQISLATQMVR[166.11].M "sp|P48643|TCPE_HUMAN,tr|E9PCA1|E9PCA1_HUMAN,tr|B7ZAR1|B7ZAR1_HUMAN,tr|E7ENZ3|E7ENZ3_HUMAN" 4 1419.7987 0.64 100772 13533 3 1419.801887 474.2735 T-complex protein 1 subunit epsilon OS=Homo sapiens OX=9606 GN=CCT5 PE=1 SV=1 11 2442.6 - 618502 - - - 2.2524 - 2.687 0.518 - 363.9 1 2 0 0.0032 12 0 0 0 5.33E+06 8.38E+06 - - - 7.0541 1 221125_WJC_METTL3_EV_vs_WT_F07.13537.13537.3 1.97E-06 28/80 R.AVYEDR[166.11]PPGSVVPTSAAEASR[166.11].A sp|Q9H1Z4|WDR13_HUMAN 1 2178.082 1.13 100774 13537 3 2178.079357 727.0346 WD repeat-containing protein 13 OS=Homo sapiens OX=9606 GN=WDR13 PE=1 SV=2 4.68 2443.2 - 1.34E+06 - - - -1.2139 - 3.752 0.501 - 503 1 2 0 -0.0026 21 0 0 0 4.94E+07 4.36E+07 - - - 7.2951 0.9994 221125_WJC_METTL3_EV_vs_WT_F07.13538.13538.3 0.00037 Oct-40 K.HNMDIGTWDNK.G "sp|Q9Y5A9|YTHD2_HUMAN,sp|Q9BYJ9|YTHD1_HUMAN" 2 1329.5772 1.4 100775 13538 3 1329.573617 444.1997 YTH domain-containing family protein 2 OS=Homo sapiens OX=9606 GN=YTHDF2 PE=1 SV=2 5.21 2443.3 - 1.21E+06 - - - -2.6836 - 1.689 0.404 - 145.7 1 2 0 -0.0036 11 0 0 0 7.60E+07 5.42E+07 - - - 4.5322 1 221125_WJC_METTL3_EV_vs_WT_F07.13540.13540.3 4.56E-11 16/52 K.NAC[160.03]DHLSGFNVC[160.03]NR.Y sp|Q9Y3B4|SF3B6_HUMAN 1 1662.6991 1.25 100777 13540 3 1662.698962 555.2403 Splicing factor 3B subunit 6 OS=Homo sapiens OX=9606 GN=SF3B6 PE=1 SV=1 6.73 2443.4 - 3.52E+06 - - - -0.0878 - 2.99 0.69 - 290.3 1 2 0 -0.0001 14 0 0 0 1.65E+08 1.32E+08 - - - 9.1435 1 221125_WJC_METTL3_EV_vs_WT_F07.13541.13541.3 9.18E-13 21/56 K.FLQEHGSDSFLAEHK[136.11].L sp|Q00688|FKBP3_HUMAN 1 1751.8358 0.07 100778 13541 3 1751.832489 584.9526 Peptidyl-prolyl cis-trans isomerase FKBP3 OS=Homo sapiens OX=9606 GN=FKBP3 PE=1 SV=1 5.27 2443.5 - 3.33E+06 - - - -1.918 - 3.468 0.618 - 538.6 1 2 0 -0.0034 15 0 0 0 6.68E+06 9.06E+07 - - - 8.6741 0.9992 221125_WJC_METTL3_EV_vs_WT_F07.13546.13546.3 1.54E-06 14/60 K.SSEHINEGETAMLVC[160.03]K[136.11].S "sp|P35613|BASI_HUMAN,tr|A0A7P0T8A7|A0A7P0T8A7_HUMAN,tr|A0A087WUV8|A0A087WUV8_HUMAN,tr|A0A7P0TA85|A0A7P0TA85_HUMAN,tr|A0A7P0TB04|A0A7P0TB04_HUMAN,tr|R4GMX5|R4GMX5_HUMAN,tr|R4GN83|R4GN83_HUMAN,tr|I3L192|I3L192_HUMAN" 8 1811.8273 1.14 100781 13546 3 1811.829908 604.9497 Basigin OS=Homo sapiens OX=9606 GN=BSG PE=1 SV=2 4.75 2444.1 - 1.98E+06 - - - 1.4201 - 2.732 0.231 - 282.1 1 2 0 0.0026 16 0 0 0 1.83E+08 1.61E+08 - - - 3.6935 0.9999 221125_WJC_METTL3_EV_vs_WT_F07.13550.13550.3 0.0004 Nov-40 K.HNMDIGTWDNK[136.11].G "sp|Q9Y5A9|YTHD2_HUMAN,sp|Q9BYJ9|YTHD1_HUMAN" 2 1337.5914 1.4 100785 13550 3 1337.593439 446.8711 YTH domain-containing family protein 2 OS=Homo sapiens OX=9606 GN=YTHDF2 PE=1 SV=2 5.21 2444.5 - 1.06E+06 - - - 1.5356 - 2.108 0.454 - 197.6 1 2 0 0.0021 11 0 0 0 7.58E+07 5.42E+07 - - - 5.7196 0.9998 221125_WJC_METTL3_EV_vs_WT_F07.13562.13562.3 0.00101 15/64 K.SELVANNVTLPAGEQRK.D "sp|P42166|LAP2A_HUMAN,sp|P42167|LAP2B_HUMAN,tr|G5E972|G5E972_HUMAN" 3 1824.9694 1.37 100793 13562 3 1824.966405 609.3304 "Lamina-associated polypeptide 2, isoform alpha OS=Homo sapiens OX=9606 GN=TMPO PE=1 SV=2" 5.86 2445.9 - 1.41E+06 - - - -1.628 - 2.321 0.394 - 147 1 2 0 -0.003 17 0 0 0 3.17E+07 2.32E+07 - - - 5.059 0.9999 221125_WJC_METTL3_EV_vs_WT_F07.13565.13565.2 4.75E-05 16/20 K.HNMDIGTWDNK[136.11].G "sp|Q9Y5A9|YTHD2_HUMAN,sp|Q9BYJ9|YTHD1_HUMAN" 2 1337.5914 1.46 100795 13565 2 1337.59108 669.803 YTH domain-containing family protein 2 OS=Homo sapiens OX=9606 GN=YTHDF2 PE=1 SV=2 5.21 2446.2 - 1.29E+06 - - - -0.228 - 2 0.54 - 442.1 1 2 0 -0.0003 11 0 0 0 4.71E+07 3.22E+07 - - - 4.9045 0.9998 221125_WJC_METTL3_EV_vs_WT_F07.13568.13568.3 2.88E-05 14/48 R.NR[166.11]EEEWDPEYTPK.S "sp|Q9Y2W1|TR150_HUMAN,tr|A0A3B3ITZ9|A0A3B3ITZ9_HUMAN" 2 1701.751 - 100798 13568 3 1701.748771 568.2576 Thyroid hormone receptor-associated protein 3 OS=Homo sapiens OX=9606 GN=THRAP3 PE=1 SV=2 4.25 2446.5 - 1.87E+06 - - - -1.3098 - 2.375 0.509 - 218.3 1 2 1 -0.0022 13 0 0 0 - - - - - 6.5595 0.9998 221125_WJC_METTL3_EV_vs_WT_F07.13573.13573.2 0.000118 15/20 K.HNMDIGTWDNK.G "sp|Q9Y5A9|YTHD2_HUMAN,sp|Q9BYJ9|YTHD1_HUMAN" 2 1329.5772 1.46 100801 13573 2 1329.579003 665.7959 YTH domain-containing family protein 2 OS=Homo sapiens OX=9606 GN=YTHDF2 PE=1 SV=2 5.21 2447.1 - 2.24E+06 - - - 1.3674 - 1.899 0.507 - 423.7 1 2 0 0.0018 11 0 0 0 4.71E+07 3.22E+07 - - - 4.5201 0.9998 221125_WJC_METTL3_EV_vs_WT_F07.13578.13578.3 0.000485 13/44 K.DDGTVIHFNNPK.V "sp|Q96K17|BT3L4_HUMAN,tr|E9PL10|E9PL10_HUMAN" 2 1355.647 0.63 100804 13578 3 1355.644848 452.8896 Transcription factor BTF3 homolog 4 OS=Homo sapiens OX=9606 GN=BTF3L4 PE=1 SV=1 5.21 2447.6 - 847292 - - - -1.5719 - 2.122 0.389 - 208 1 2 0 -0.0021 12 0 0 0 2.97E+07 4.69E+07 - - - 4.9618 1 221125_WJC_METTL3_EV_vs_WT_F07.13579.13579.3 0.000719 16/52 R.FAQHGTFEYEYSQR[166.11].W "sp|P23246|SFPQ_HUMAN,tr|H0Y9K7|H0Y9K7_HUMAN" 2 1771.783 0.68 100805 13579 3 1771.783431 591.6016 "Splicing factor, proline- and glutamine-rich OS=Homo sapiens OX=9606 GN=SFPQ PE=1 SV=2" 5.4 2447.8 - 1.74E+06 - - - 0.2613 - 2.699 0.444 - 247.7 1 2 0 0.0005 14 0 0 0 9.29E+06 1.37E+07 - - - 6.1286 0.9999 221125_WJC_METTL3_EV_vs_WT_F07.13582.13582.4 4.83E-06 19/84 K.KAEAGAGSATEFQFR.G "sp|Q9NQ39|RS10L_HUMAN,sp|P46783|RS10_HUMAN" 2 1568.7583 1.25 100808 13582 4 1568.755151 393.1969 Putative 40S ribosomal protein S10-like OS=Homo sapiens OX=9606 GN=RPS10P5 PE=5 SV=1 6.14 2448.2 - 892673 - - - -2.0201 - 3.13 0.484 - 231.1 1 2 0 -0.0032 15 0 0 0 2.27E+07 1.82E+07 - - - 3.8461 0.9999 221125_WJC_METTL3_EV_vs_WT_F07.13588.13588.3 3.35E-05 Dec-48 R.SIFQHIQSAQSQR.S "sp|Q9Y2W1|TR150_HUMAN,tr|A0A3B3ITZ9|A0A3B3ITZ9_HUMAN" 2 1528.7746 2.58 100810 13588 3 1528.772589 510.5988 Thyroid hormone receptor-associated protein 3 OS=Homo sapiens OX=9606 GN=THRAP3 PE=1 SV=2 9.49 2448.9 - 2.69E+07 - - - -1.3409 - 2.053 0.493 - 145.3 1 2 0 -0.0021 13 0 0 0 4.88E+10 1.89E+10 - - - 5.9861 1 221125_WJC_METTL3_EV_vs_WT_F07.13590.13590.3 7.45E-06 16/56 K.KAEAGAGSATEFQFR[166.11].G "sp|Q9NQ39|RS10L_HUMAN,sp|P46783|RS10_HUMAN" 2 1578.7666 - 100812 13590 3 1578.768749 527.2628 Putative 40S ribosomal protein S10-like OS=Homo sapiens OX=9606 GN=RPS10P5 PE=5 SV=1 6.14 2449 - 4.21E+06 - - - 1.3675 - 2.802 0.498 - 379.7 1 2 0 0.0022 15 0 0 0 - - - - - 6.7801 0.9999 221125_WJC_METTL3_EV_vs_WT_F07.13591.13591.3 8.74E-06 16/64 K.SELVANNVTLPAGEQR[166.11]K[136.11].D "sp|P42166|LAP2A_HUMAN,sp|P42167|LAP2B_HUMAN,tr|G5E972|G5E972_HUMAN" 3 1842.9918 1.37 100813 13591 3 1842.990554 615.3379 "Lamina-associated polypeptide 2, isoform alpha OS=Homo sapiens OX=9606 GN=TMPO PE=1 SV=2" 5.86 2449.2 - 1.91E+06 - - - -0.701 - 2.636 0.426 - 218.8 1 2 0 -0.0013 17 0 0 0 3.17E+07 2.32E+07 - - - 5.7378 0.9999 221125_WJC_METTL3_EV_vs_WT_F07.13599.13599.3 0.000167 Nov-48 R.SIFQHIQSAQSQR[166.11].S "sp|Q9Y2W1|TR150_HUMAN,tr|A0A3B3ITZ9|A0A3B3ITZ9_HUMAN" 2 1538.7829 2.58 100818 13599 3 1538.783979 513.9349 Thyroid hormone receptor-associated protein 3 OS=Homo sapiens OX=9606 GN=THRAP3 PE=1 SV=2 9.49 2450.2 - 6.00E+06 - - - 0.6954 - 2.01 0.471 - 109.4 1 2 0 0.0011 13 0 0 0 4.88E+10 1.89E+10 - - - 5.6837 1 221125_WJC_METTL3_EV_vs_WT_F07.13600.13600.2 4.13E-09 17/24 R.SIFQHIQSAQSQR.S "sp|Q9Y2W1|TR150_HUMAN,tr|A0A3B3ITZ9|A0A3B3ITZ9_HUMAN" 2 1528.7746 2.51 100819 13600 2 1528.77245 765.3946 Thyroid hormone receptor-associated protein 3 OS=Homo sapiens OX=9606 GN=THRAP3 PE=1 SV=2 9.49 2450.3 - 2.81E+06 - - - -1.4319 - 3.044 0.626 - 1281.2 1 2 0 -0.0022 13 0 0 0 8.98E+09 3.58E+09 - - - 6.5209 0.9996 221125_WJC_METTL3_EV_vs_WT_F07.13601.13601.2 2.57E-05 13/22 R.AQVQEFC[160.03]DYGTK[136.11].E "sp|Q86U44|MTA70_HUMAN,tr|H0YFV6|H0YFV6_HUMAN" 2 1452.6435 0.01 100820 13601 2 1452.639676 727.329 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 4.37 2450.3 - 5.36E+06 - - - -2.6187 - 2.57 0.476 - 497.8 1 2 0 -0.0038 12 0 0 0 1.15E+07 8.62E+08 - - - 5.0391 0.9999 221125_WJC_METTL3_EV_vs_WT_F07.13602.13602.3 1.45E-06 17/60 K.VTVAGLAGKDPVQC[160.03]SR.D "sp|Q99497|PARK7_HUMAN,tr|K7ELW0|K7ELW0_HUMAN" 2 1656.8617 2.69 100821 13602 3 1656.863989 553.2945 Parkinson disease protein 7 OS=Homo sapiens OX=9606 GN=PARK7 PE=1 SV=2 8.19 2450.4 - 4.52E+06 - - - 1.3574 - 3.257 0.555 - 255 1 2 1 0.0022 16 0 0 0 1.51E+08 5.62E+07 - - - 7.7569 0.976 221125_WJC_METTL3_EV_vs_WT_F07.13615.13615.2 0.00749 12-Aug W.DPEYTPK.S "sp|Q9NYF8|BCLF1_HUMAN,sp|Q9Y2W1|TR150_HUMAN,tr|A0A3B3ITZ9|A0A3B3ITZ9_HUMAN,tr|H0YF14|H0YF14_HUMAN" 4 848.3916 4.18 100830 13615 2 848.390458 425.2031 Bcl-2-associated transcription factor 1 OS=Homo sapiens OX=9606 GN=BCLAF1 PE=1 SV=2 4.37 2451.9 - 1.42E+06 - - - -1.3449 - 1.735 0.384 - 252.7 1 1 0 -0.0011 7 0 0 0 5.56E+07 1.33E+07 - - - 3.6228 0.9985 221125_WJC_METTL3_EV_vs_WT_F07.13622.13622.3 0.000728 16/60 R.QISDGER[166.11]EELNLTANR[166.11].L sp|O95816|BAG2_HUMAN 1 1863.919 0.25 100835 13622 3 1863.917023 622.3136 BAG family molecular chaperone regulator 2 OS=Homo sapiens OX=9606 GN=BAG2 PE=1 SV=1 4.41 2452.8 - 2.40E+06 - - - -1.0381 - 2.195 0.323 - 299.1 1 2 1 -0.0019 16 0 0 0 6.90E+07 2.77E+08 - - - 4.1578 0.9875 221125_WJC_METTL3_EV_vs_WT_F07.13627.13627.3 0.197 Dec-80 K.ADPPPEESQAPQAQTAAAEAP.- "sp|O95785|WIZ_HUMAN,tr|A0A669KBG4|A0A669KBG4_HUMAN,tr|A0A2R8YFV2|A0A2R8YFV2_HUMAN,tr|A0A669KAV7|A0A669KAV7_HUMAN,tr|M0QXA7|M0QXA7_HUMAN,tr|A0A669KBH9|A0A669KBH9_HUMAN,tr|B9EGQ5|B9EGQ5_HUMAN" 7 2074.9443 - 100838 13627 3 2074.941655 692.6554 Protein Wiz OS=Homo sapiens OX=9606 GN=WIZ PE=1 SV=2 3.5 2453.5 - 1.17E+06 - - - -1.2955 - 1.672 0.178 - 104.2 1 2 0 -0.0027 21 0 0 0 - - - - - 1.7561 0.8156 221125_WJC_METTL3_EV_vs_WT_F07.13632.13632.3 0.0035 Dec-48 R.THGMAFIRAR[166.11]QGA.V sp|Q8N1G0|ZN687_HUMAN 1 1424.7335 - 100841 13632 3 1424.733557 475.9184 Zinc finger protein 687 OS=Homo sapiens OX=9606 GN=ZNF687 PE=1 SV=1 12 2454.1 - 2.55E+06 - - - 0.0709 - 2.008 0.309 - 109.1 1 1 2 0.0001 13 0 0 0 - - - - - 3.8752 0.9981 221125_WJC_METTL3_EV_vs_WT_F07.13639.13639.3 0.00658 18/64 R.FSALQQAVPTESTDNR[166.11]R[166.11].V "sp|Q04637|IF4G1_HUMAN,tr|H7C044|H7C044_HUMAN,tr|E7EUU4|E7EUU4_HUMAN,tr|E9PGM1|E9PGM1_HUMAN,tr|E7EX73|E7EX73_HUMAN,tr|A0A7I2Y1C3|A0A7I2Y1C3_HUMAN" 6 1938.9662 0.83 100844 13639 3 1938.954692 647.3294 Eukaryotic translation initiation factor 4 gamma 1 OS=Homo sapiens OX=9606 GN=EIF4G1 PE=1 SV=4 6.07 2455 - 1.80E+06 - - - -5.9573 - 2.986 0.396 - 395.6 1 2 0 -0.0116 17 0 0 0 8.15E+07 9.86E+07 - - - 5.7154 0.9998 221125_WJC_METTL3_EV_vs_WT_F07.13640.13640.4 0.000159 16/72 R.K[136.11]LDALC[160.03]NIHENIR[166.11].V "sp|P53621|COPA_HUMAN,tr|A0A3B3ISC6|A0A3B3ISC6_HUMAN,tr|A0A3B3ITV3|A0A3B3ITV3_HUMAN,tr|A0A3B3IS84|A0A3B3IS84_HUMAN,tr|A0A3B3IU89|A0A3B3IU89_HUMAN,tr|A0A3B3IT15|A0A3B3IT15_HUMAN" 6 1612.8474 0.88 100845 13640 4 1612.84956 404.2191 Coatomer subunit alpha OS=Homo sapiens OX=9606 GN=COPA PE=1 SV=2 6.74 2455.1 - 702014 - - - 1.3206 - 2.355 0.395 - 196.1 1 2 0 0.0021 13 0 0 0 4.82E+06 5.44E+06 - - - 2.9811 0.9998 221125_WJC_METTL3_EV_vs_WT_F07.13641.13641.4 0.000424 16/78 R.FGLESHAHTIQIC[160.03]K[136.11].L "sp|Q8NE71|ABCF1_HUMAN,tr|A0A0G2JIC2|A0A0G2JIC2_HUMAN,tr|Q5STZ8|Q5STZ8_HUMAN,tr|H0YGW7|H0YGW7_HUMAN" 4 1647.8283 0.81 100846 13641 4 1647.82379 412.9643 ATP-binding cassette sub-family F member 1 OS=Homo sapiens OX=9606 GN=ABCF1 PE=1 SV=2 6.91 2455.3 - 2.11E+06 - - - -2.7133 - 2.623 0.424 - 94.6 1 2 0 -0.0045 14 0 0 0 2.93E+07 3.63E+07 - - - 3.2662 0.9999 221125_WJC_METTL3_EV_vs_WT_F07.13644.13644.3 0.0136 Dec-52 R.FGLESHAHTIQIC[160.03]K[136.11].L "sp|Q8NE71|ABCF1_HUMAN,tr|A0A0G2JIC2|A0A0G2JIC2_HUMAN,tr|Q5STZ8|Q5STZ8_HUMAN,tr|H0YGW7|H0YGW7_HUMAN" 4 1647.8283 1.07 100847 13644 3 1647.82885 550.2834 ATP-binding cassette sub-family F member 1 OS=Homo sapiens OX=9606 GN=ABCF1 PE=1 SV=2 6.91 2455.6 - 2.37E+06 - - - 0.3574 - 2.636 0.356 - 90.7 1 2 0 0.0006 14 0 0 0 2.72E+07 2.54E+07 - - - 5.0847 0.9996 221125_WJC_METTL3_EV_vs_WT_F07.13646.13646.3 4.04E-06 16/60 R.QISDGEREELNLTANR.L sp|O95816|BAG2_HUMAN 1 1843.9024 0.22 100849 13646 3 1843.897747 615.6414 BAG family molecular chaperone regulator 2 OS=Homo sapiens OX=9606 GN=BAG2 PE=1 SV=1 4.41 2455.9 - 1.45E+06 - - - -2.5332 - 2.245 0.518 - 247.8 1 2 1 -0.0047 16 0 0 0 6.06E+07 2.70E+08 - - - 6.3889 0.9957 221125_WJC_METTL3_EV_vs_WT_F07.13649.13649.3 0.0543 Aug-52 R.FGLESHAHTIQIC[160.03]K.L "sp|Q8NE71|ABCF1_HUMAN,tr|A0A0G2JIC2|A0A0G2JIC2_HUMAN,tr|Q5STZ8|Q5STZ8_HUMAN,tr|H0YGW7|H0YGW7_HUMAN" 4 1639.8141 1.07 100850 13649 3 1639.812274 547.612 ATP-binding cassette sub-family F member 1 OS=Homo sapiens OX=9606 GN=ABCF1 PE=1 SV=2 6.91 2456.3 - 2.61E+06 - - - -1.0898 - 1.635 0.225 - 37.9 1 2 0 -0.0018 14 0 0 0 2.72E+07 2.54E+07 - - - 2.3546 1 221125_WJC_METTL3_EV_vs_WT_F07.13650.13650.3 0.00319 16/48 R.K[136.11]LDALC[160.03]NIHENIR[166.11].V "sp|P53621|COPA_HUMAN,tr|A0A3B3ISC6|A0A3B3ISC6_HUMAN,tr|A0A3B3ITV3|A0A3B3ITV3_HUMAN,tr|A0A3B3IS84|A0A3B3IS84_HUMAN,tr|A0A3B3IU89|A0A3B3IU89_HUMAN,tr|A0A3B3IT15|A0A3B3IT15_HUMAN" 6 1612.8474 0.53 100851 13650 3 1612.849083 538.6231 Coatomer subunit alpha OS=Homo sapiens OX=9606 GN=COPA PE=1 SV=2 6.74 2456.4 - 632025 - - - 1.0249 - 3.087 0.46 - 333.7 1 2 0 0.0017 13 0 0 0 7.73E+06 1.45E+07 - - - 6.7243 0.9999 221125_WJC_METTL3_EV_vs_WT_F07.13651.13651.4 1.83E-06 18/84 R.LLLEGISSTHAHHLR.C "sp|Q9Y371|SHLB1_HUMAN,tr|A0A087WW40|A0A087WW40_HUMAN" 2 1682.9216 1.06 100852 13651 4 1682.917804 421.7377 Endophilin-B1 OS=Homo sapiens OX=9606 GN=SH3GLB1 PE=1 SV=1 7.03 2456.5 - 856852 - - - -2.2782 - 3.184 0.454 - 324.2 1 2 0 -0.0038 15 0 0 0 2.56E+07 2.41E+07 - - - 3.5909 0.9999 221125_WJC_METTL3_EV_vs_WT_F07.13656.13656.3 8.96E-05 15/60 R.FAEVEC[160.03]LAESHQHLSK[136.11].E "sp|Q14839|CHD4_HUMAN,tr|A0A2R8Y4X2|A0A2R8Y4X2_HUMAN,tr|A0A2U3TZM0|A0A2U3TZM0_HUMAN,tr|A0A2R8YD40|A0A2R8YD40_HUMAN,tr|A0A2R8Y5J0|A0A2R8Y5J0_HUMAN,tr|A0A2R8Y425|A0A2R8Y425_HUMAN,tr|A0A2R8YFK9|A0A2R8YFK9_HUMAN,tr|A0A0C4DGG9|A0A0C4DGG9_HUMAN,tr|A0A2R8YFD8|A0A2R8YFD8_HUMAN,tr|A0A2R8YDW2|A0A2R8YDW2_HUMAN,tr|A0A2R8Y7I0|A0A2R8Y7I0_HUMAN,tr|F5GWX5|F5GWX5_HUMAN,tr|A0A2R8Y7M9|A0A2R8Y7M9_HUMAN,tr|A0A2R8Y521|A0A2R8Y521_HUMAN,tr|A0A2R8YDJ9|A0A2R8YDJ9_HUMAN,tr|A0A2R8Y212|A0A2R8Y212_HUMAN" 16 1891.8978 1.99 100855 13656 3 1891.89998 631.6399 Chromodomain-helicase-DNA-binding protein 4 OS=Homo sapiens OX=9606 GN=CHD4 PE=1 SV=2 5.33 2457.2 - 861299 - - - 1.1539 - 2.47 0.428 - 97.1 1 2 0 0.0022 16 0 0 0 4.35E+07 2.19E+07 - - - 5.6313 0.9998 221125_WJC_METTL3_EV_vs_WT_F07.13657.13657.3 0.00024 15/64 R.FSALQQAVPTESTDNRR.V "sp|Q04637|IF4G1_HUMAN,tr|H7C044|H7C044_HUMAN,tr|E7EUU4|E7EUU4_HUMAN,tr|E9PGM1|E9PGM1_HUMAN,tr|E7EX73|E7EX73_HUMAN,tr|A0A7I2Y1C3|A0A7I2Y1C3_HUMAN" 6 1918.9497 0.83 100856 13657 3 1918.955009 640.6572 Eukaryotic translation initiation factor 4 gamma 1 OS=Homo sapiens OX=9606 GN=EIF4G1 PE=1 SV=4 6.07 2457.2 - 2.31E+06 - - - 2.7651 - 2.582 0.433 - 168.9 1 2 0 0.0053 17 0 0 0 8.15E+07 9.86E+07 - - - 5.7624 1 221125_WJC_METTL3_EV_vs_WT_F07.13663.13663.4 9.49E-07 17/90 R.FAEVEC[160.03]LAESHQHLSK.E "sp|Q14839|CHD4_HUMAN,tr|A0A2R8Y4X2|A0A2R8Y4X2_HUMAN,tr|A0A2U3TZM0|A0A2U3TZM0_HUMAN,tr|A0A2R8YD40|A0A2R8YD40_HUMAN,tr|A0A2R8Y5J0|A0A2R8Y5J0_HUMAN,tr|A0A2R8Y425|A0A2R8Y425_HUMAN,tr|A0A2R8YFK9|A0A2R8YFK9_HUMAN,tr|A0A0C4DGG9|A0A0C4DGG9_HUMAN,tr|A0A2R8YFD8|A0A2R8YFD8_HUMAN,tr|A0A2R8YDW2|A0A2R8YDW2_HUMAN,tr|A0A2R8Y7I0|A0A2R8Y7I0_HUMAN,tr|F5GWX5|F5GWX5_HUMAN,tr|A0A2R8Y7M9|A0A2R8Y7M9_HUMAN,tr|A0A2R8Y521|A0A2R8Y521_HUMAN,tr|A0A2R8YDJ9|A0A2R8YDJ9_HUMAN,tr|A0A2R8Y212|A0A2R8Y212_HUMAN" 16 1883.8836 1.07 100860 13663 4 1883.883419 471.9782 Chromodomain-helicase-DNA-binding protein 4 OS=Homo sapiens OX=9606 GN=CHD4 PE=1 SV=2 5.33 2458 - 1.55E+06 - - - -0.0945 - 3.231 0.494 - 312.8 1 2 0 -0.0002 16 0 0 0 4.29E+07 4.01E+07 - - - 3.9389 1 221125_WJC_METTL3_EV_vs_WT_F07.13667.13667.4 2.87E-05 17/84 R.LLLEGISSTHAHHLR[166.11].C "sp|Q9Y371|SHLB1_HUMAN,tr|A0A087WW40|A0A087WW40_HUMAN" 2 1692.9299 1.19 100864 13667 4 1692.929002 424.2398 Endophilin-B1 OS=Homo sapiens OX=9606 GN=SH3GLB1 PE=1 SV=1 7.03 2458.4 - 857758 - - - -0.5346 - 2.93 0.501 - 280.6 1 2 0 -0.0009 15 0 0 0 2.99E+07 2.51E+07 - - - 3.9711 0.9532 221125_WJC_METTL3_EV_vs_WT_F07.13668.13668.2 0.00429 30-Sep R.QISDGER[166.11]EELNLTANR[166.11].L sp|O95816|BAG2_HUMAN 1 1863.919 0.06 100865 13668 2 1863.912875 932.9668 BAG family molecular chaperone regulator 2 OS=Homo sapiens OX=9606 GN=BAG2 PE=1 SV=1 4.41 2458.6 - 407154 - - - -3.2636 - 1.628 0.315 - 56.3 1 2 1 -0.0061 16 0 0 0 4.50E+05 7.40E+06 - - - 2.5639 1 221125_WJC_METTL3_EV_vs_WT_F07.13671.13671.4 3.23E-09 15/90 R.FAEVEC[160.03]LAESHQHLSK[136.11].E "sp|Q14839|CHD4_HUMAN,tr|A0A2R8Y4X2|A0A2R8Y4X2_HUMAN,tr|A0A2U3TZM0|A0A2U3TZM0_HUMAN,tr|A0A2R8YD40|A0A2R8YD40_HUMAN,tr|A0A2R8Y5J0|A0A2R8Y5J0_HUMAN,tr|A0A2R8Y425|A0A2R8Y425_HUMAN,tr|A0A2R8YFK9|A0A2R8YFK9_HUMAN,tr|A0A0C4DGG9|A0A0C4DGG9_HUMAN,tr|A0A2R8YFD8|A0A2R8YFD8_HUMAN,tr|A0A2R8YDW2|A0A2R8YDW2_HUMAN,tr|A0A2R8Y7I0|A0A2R8Y7I0_HUMAN,tr|F5GWX5|F5GWX5_HUMAN,tr|A0A2R8Y7M9|A0A2R8Y7M9_HUMAN,tr|A0A2R8Y521|A0A2R8Y521_HUMAN,tr|A0A2R8YDJ9|A0A2R8YDJ9_HUMAN,tr|A0A2R8Y212|A0A2R8Y212_HUMAN" 16 1891.8978 1.07 100866 13671 4 1891.897992 473.9817 Chromodomain-helicase-DNA-binding protein 4 OS=Homo sapiens OX=9606 GN=CHD4 PE=1 SV=2 5.33 2459 - 3.36E+06 - - - 0.1031 - 3.167 0.512 - 297.8 1 2 0 0.0002 16 0 0 0 4.29E+07 4.01E+07 - - - 4.0885 1 221125_WJC_METTL3_EV_vs_WT_F07.13672.13672.3 1.48E-08 17/60 R.FAEVEC[160.03]LAESHQHLSK.E "sp|Q14839|CHD4_HUMAN,tr|A0A2R8Y4X2|A0A2R8Y4X2_HUMAN,tr|A0A2U3TZM0|A0A2U3TZM0_HUMAN,tr|A0A2R8YD40|A0A2R8YD40_HUMAN,tr|A0A2R8Y5J0|A0A2R8Y5J0_HUMAN,tr|A0A2R8Y425|A0A2R8Y425_HUMAN,tr|A0A2R8YFK9|A0A2R8YFK9_HUMAN,tr|A0A0C4DGG9|A0A0C4DGG9_HUMAN,tr|A0A2R8YFD8|A0A2R8YFD8_HUMAN,tr|A0A2R8YDW2|A0A2R8YDW2_HUMAN,tr|A0A2R8Y7I0|A0A2R8Y7I0_HUMAN,tr|F5GWX5|F5GWX5_HUMAN,tr|A0A2R8Y7M9|A0A2R8Y7M9_HUMAN,tr|A0A2R8Y521|A0A2R8Y521_HUMAN,tr|A0A2R8YDJ9|A0A2R8YDJ9_HUMAN,tr|A0A2R8Y212|A0A2R8Y212_HUMAN" 16 1883.8836 1.19 100867 13672 3 1883.885537 628.9685 Chromodomain-helicase-DNA-binding protein 4 OS=Homo sapiens OX=9606 GN=CHD4 PE=1 SV=2 5.33 2459 - 1.56E+06 - - - 1.0298 - 2.951 0.596 - 157.6 1 2 0 0.0019 16 0 0 0 2.40E+07 2.01E+07 - - - 7.9609 1 221125_WJC_METTL3_EV_vs_WT_F07.13675.13675.3 0.000329 13/60 R.FFDENESPVDPQHGSK.L "sp|Q6P4E1|GOLM2_HUMAN,tr|A0A3B3IRW9|A0A3B3IRW9_HUMAN" 2 1831.8013 2.13 100870 13675 3 1831.800802 611.6077 Protein GOLM2 OS=Homo sapiens OX=9606 GN=GOLM2 PE=1 SV=2 4.31 2459.4 - 503190 - - - -0.2757 - 2.428 0.566 - 163.8 1 2 0 -0.0005 16 0 0 0 3.42E+07 1.60E+07 - - - 7.1263 1 221125_WJC_METTL3_EV_vs_WT_F07.13676.13676.2 6.31E-07 24-Nov K.SQGLSQLYHNQSQ.G "sp|P78344|IF4G2_HUMAN,tr|D3DQV9|D3DQV9_HUMAN" 2 1488.6957 - 100871 13676 2 1488.696894 745.3551 Eukaryotic translation initiation factor 4 gamma 2 OS=Homo sapiens OX=9606 GN=EIF4G2 PE=1 SV=1 6.46 2459.5 - 500118 - - - 0.7886 - 2.473 0.648 - 378.3 1 1 0 0.0012 13 0 0 0 - - - - - 6.1506 1 221125_WJC_METTL3_EV_vs_WT_F07.13678.13678.3 5.13E-05 15/56 R.LLLEGISSTHAHHLR.C "sp|Q9Y371|SHLB1_HUMAN,tr|A0A087WW40|A0A087WW40_HUMAN" 2 1682.9216 18.85 100873 13678 3 1682.924519 561.9812 Endophilin-B1 OS=Homo sapiens OX=9606 GN=SH3GLB1 PE=1 SV=1 7.03 2459.8 - 304636 - - - 1.7119 - 3.187 0.508 - 263.5 1 2 0 0.0029 15 0 0 0 6.80E+06 3.61E+05 - - - 7.2274 0.9436 221125_WJC_METTL3_EV_vs_WT_F07.13681.13681.4 1.74E-06 16/90 R.ADFREPNAEVPRPIPH.L "sp|Q9NX40|OCAD1_HUMAN,tr|D6RA54|D6RA54_HUMAN,tr|D6RF01|D6RF01_HUMAN,tr|D6RBC5|D6RBC5_HUMAN,tr|D6R918|D6R918_HUMAN,tr|D6RF07|D6RF07_HUMAN,tr|D6RG39|D6RG39_HUMAN,tr|D6RDI5|D6RDI5_HUMAN,tr|D6RIT9|D6RIT9_HUMAN,tr|D6RC55|D6RC55_HUMAN" 10 1843.9329 1.78 100874 13681 4 1843.933474 461.9905 OCIA domain-containing protein 1 OS=Homo sapiens OX=9606 GN=OCIAD1 PE=1 SV=1 5.45 2460.2 - 809107 - - - 0.295 - 2.424 0.405 - 201.7 1 1 1 0.0005 16 0 0 0 2.80E+07 1.58E+07 - - - 3.0629 0.9796 221125_WJC_METTL3_EV_vs_WT_F07.13686.13686.3 0.988 Oct-52 K.QGLETFK[136.11]PDYSEQK[136.11].G sp|Q7Z417|NUFP2_HUMAN 1 1684.8279 1.71 100879 13686 3 1684.832385 562.6166 Nuclear fragile X mental retardation-interacting protein 2 OS=Homo sapiens OX=9606 GN=NUFIP2 PE=1 SV=1 4.68 2460.8 - 489679 - - - 2.6525 - 1.888 0.162 - 84.4 1 2 0 0.0045 14 0 0 0 7.81E+07 4.57E+07 - - - 2.0338 0.9997 221125_WJC_METTL3_EV_vs_WT_F07.13689.13689.2 7.01E-05 24-Nov R.SIFQHIQSAQSQR[166.11].S "sp|Q9Y2W1|TR150_HUMAN,tr|A0A3B3ITZ9|A0A3B3ITZ9_HUMAN" 2 1538.7829 2.51 100882 13689 2 1538.78121 770.3987 Thyroid hormone receptor-associated protein 3 OS=Homo sapiens OX=9606 GN=THRAP3 PE=1 SV=2 9.49 2461.1 - 256483 - - - -1.1041 - 2.278 0.366 - 435.6 1 2 0 -0.0017 13 0 0 0 8.98E+09 3.58E+09 - - - 3.8568 0.9967 221125_WJC_METTL3_EV_vs_WT_F07.13695.13695.3 2.42E-06 13/48 L.KDQIVDLTVGNNK.T sp|P35527|K1C9_HUMAN 1 1442.7729 999 100886 13695 3 1442.775161 481.9316 "Keratin, type I cytoskeletal 9 OS=Homo sapiens OX=9606 GN=KRT9 PE=1 SV=3" 5.96 2461.9 - 1.48E+06 - - - 1.5616 - 3.055 0.486 - 269 1 1 0 0.0023 13 0 0 0 4.35E+07 0.00E+00 - - - 6.9857 0.9999 221125_WJC_METTL3_EV_vs_WT_F07.13696.13696.3 3.60E-05 16/52 K.QGLETFKPDYSEQK.G sp|Q7Z417|NUFP2_HUMAN 1 1668.7995 1.7 100887 13696 3 1668.803705 557.2738 Nuclear fragile X mental retardation-interacting protein 2 OS=Homo sapiens OX=9606 GN=NUFIP2 PE=1 SV=1 4.68 2462.1 - 1.08E+06 - - - 2.5102 - 2.66 0.476 - 240.4 1 2 0 0.0042 14 0 0 0 7.81E+07 4.60E+07 - - - 6.4457 0.9996 221125_WJC_METTL3_EV_vs_WT_F07.13700.13700.2 0.000605 Nov-36 R.SAVQKPPSTGSAPAIESVD.- sp|Q9NUQ3|TXLNG_HUMAN 1 1839.9214 1.66 100891 13700 2 1839.924475 920.968 Gamma-taxilin OS=Homo sapiens OX=9606 GN=TXLNG PE=1 SV=2 4.67 2462.5 - 444177 - - - 1.6593 - 2.128 0.401 - 290 1 2 0 0.0031 19 0 0 0 5.21E+06 3.15E+06 - - - 3.8585 0.9941 221125_WJC_METTL3_EV_vs_WT_F07.13701.13701.3 0.00632 Dec-56 R.DVDIIDHHDNTYTVK[136.11].Y "sp|P21333|FLNA_HUMAN,tr|A0A7P0NMY4|A0A7P0NMY4_HUMAN,tr|Q60FE5|Q60FE5_HUMAN" 3 1791.8519 1.1 100892 13701 3 1791.856798 598.2912 Filamin-A OS=Homo sapiens OX=9606 GN=FLNA PE=1 SV=4 4.54 2462.6 - 427268 - - - 2.7374 - 2.059 0.221 - 73 1 2 0 0.0049 15 0 0 0 7.25E+07 6.59E+07 - - - 2.8871 0.9997 221125_WJC_METTL3_EV_vs_WT_F07.13706.13706.2 0.00115 Aug-34 R.VPSLTTVPQTQGQTTAQK[136.11].V sp|Q9BW19|KIFC1_HUMAN 1 1892.0095 0.42 100897 13706 2 1892.008115 947.012 Kinesin-like protein KIFC1 OS=Homo sapiens OX=9606 GN=KIFC1 PE=1 SV=2 8.72 2463.2 - 204750 - - - -0.7088 - 1.622 0.467 - 94.5 1 2 0 -0.0013 18 0 0 0 5.69E+05 1.36E+06 - - - 3.6789 0.9387 221125_WJC_METTL3_EV_vs_WT_F07.13712.13712.3 0.00237 14/68 R.TQSSASLAASYAAQQHPQ.A sp|Q96PK6|RBM14_HUMAN 1 1844.8653 - 100901 13712 3 1844.857386 615.9624 RNA-binding protein 14 OS=Homo sapiens OX=9606 GN=RBM14 PE=1 SV=2 6.4 2463.9 - 2.66E+06 - - - -4.2919 - 2.635 0.42 - 145.2 1 1 0 -0.0079 18 0 0 0 - - - - - 5.633 1 221125_WJC_METTL3_EV_vs_WT_F07.13715.13715.3 0.00019 23/80 K.SPAVATSTAAPPPPSSPLPSK.S "sp|Q14157|UBP2L_HUMAN,tr|F8W726|F8W726_HUMAN" 2 1959.0313 2.84 100904 13715 3 1959.030925 654.0177 Ubiquitin-associated protein 2-like OS=Homo sapiens OX=9606 GN=UBAP2L PE=1 SV=2 8.47 2464.2 - 1.27E+06 - - - -0.195 - 4.235 0.502 - 727.7 1 2 0 -0.0004 21 0 0 0 1.94E+09 6.82E+08 - - - 7.5971 1 221125_WJC_METTL3_EV_vs_WT_F07.13723.13723.3 0.000504 14/56 R.DVDIIDHHDNTYTVK.Y "sp|P21333|FLNA_HUMAN,tr|A0A7P0NMY4|A0A7P0NMY4_HUMAN,tr|Q60FE5|Q60FE5_HUMAN" 3 1783.8377 1.1 100910 13723 3 1783.837894 595.6198 Filamin-A OS=Homo sapiens OX=9606 GN=FLNA PE=1 SV=4 4.54 2465.1 - 1.99E+06 - - - 0.1127 - 2.886 0.499 - 146.1 1 2 0 0.0002 15 0 0 0 7.25E+07 6.59E+07 - - - 6.8689 1 221125_WJC_METTL3_EV_vs_WT_F07.13724.13724.4 3.27E-05 Dec-84 R.DVDIIDHHDNTYTVK.Y "sp|P21333|FLNA_HUMAN,tr|A0A7P0NMY4|A0A7P0NMY4_HUMAN,tr|Q60FE5|Q60FE5_HUMAN" 3 1783.8377 1.48 100911 13724 4 1783.835731 446.9667 Filamin-A OS=Homo sapiens OX=9606 GN=FLNA PE=1 SV=4 4.54 2465.2 - 1.73E+06 - - - -1.0999 - 2.478 0.53 - 79 1 2 0 -0.002 15 0 0 0 6.99E+07 4.73E+07 - - - 4.1633 1 221125_WJC_METTL3_EV_vs_WT_F07.13729.13729.2 2.43E-15 21/40 K.SPAVATSTAAPPPPSSPLPSK.S "sp|Q14157|UBP2L_HUMAN,tr|F8W726|F8W726_HUMAN" 2 1959.0313 2.8 100914 13729 2 1959.032198 980.5229 Ubiquitin-associated protein 2-like OS=Homo sapiens OX=9606 GN=UBAP2L PE=1 SV=2 8.47 2465.9 - 1.38E+06 - - - 0.4548 - 4.352 0.621 - 738.4 1 2 0 0.0009 21 0 0 0 9.04E+08 3.23E+08 - - - 7.2431 1 221125_WJC_METTL3_EV_vs_WT_F07.13732.13732.2 4.74E-11 17/28 Q.VQEFC[160.03]DYGTK[136.11]EEC[160.03]MK[136.11].A "sp|Q86U44|MTA70_HUMAN,tr|H0YFV6|H0YFV6_HUMAN" 2 1938.8133 0.001 100917 13732 2 1938.806751 970.4139 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 4.41 2466.3 - 949430 - - - -3.3629 - 3.434 0.689 - 879.3 1 1 1 -0.0065 15 0 0 0 0.00E+00 8.00E+07 - - - 7.1611 1 221125_WJC_METTL3_EV_vs_WT_F07.13741.13741.4 9.04E-11 20/96 R.AQVQEFC[160.03]DYGTK[136.11]EEC[160.03]MK[136.11].A "sp|Q86U44|MTA70_HUMAN,tr|H0YFV6|H0YFV6_HUMAN" 2 2137.909 0.001 100921 13741 4 2137.905556 535.4845 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 4.41 2467.3 - 3.08E+06 - - - -1.5936 - 3.99 0.71 - 370.1 1 2 1 -0.0034 17 0 0 0 0.00E+00 1.40E+08 - - - 5.8853 1 221125_WJC_METTL3_EV_vs_WT_F07.13744.13744.2 4.32E-10 21/32 R.AQVQEFC[160.03]DYGTK[136.11]EEC[160.03]MK.A "sp|Q86U44|MTA70_HUMAN,tr|H0YFV6|H0YFV6_HUMAN" 2 2129.8948 - 100922 13744 2 2130.883962 1065.9547 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 4.41 2467.7 - 6.39E+06 - - - 464.4356 - 4.003 0.686 - 1036.3 1 2 1 0.9892 17 0 0 0 - - - - - 7.2073 1 221125_WJC_METTL3_EV_vs_WT_F07.13746.13746.3 2.38E-05 20/80 K.SPAVATSTAAPPPPSSPLPSK[136.11].S "sp|Q14157|UBP2L_HUMAN,tr|F8W726|F8W726_HUMAN" 2 1967.0455 2.85 100923 13746 3 1967.045005 656.6891 Ubiquitin-associated protein 2-like OS=Homo sapiens OX=9606 GN=UBAP2L PE=1 SV=2 8.47 2467.9 - 4.07E+06 - - - -0.2552 - 3.691 0.493 - 495.7 1 2 0 -0.0005 21 0 0 0 1.95E+09 6.86E+08 - - - 7.1672 1 221125_WJC_METTL3_EV_vs_WT_F07.13748.13748.3 1.74E-11 20/64 R.AQVQEFC[160.03]DYGTKEEC[160.03]MK.A "sp|Q86U44|MTA70_HUMAN,tr|H0YFV6|H0YFV6_HUMAN" 2 2121.8806 0.01 100924 13748 3 2122.886675 708.3008 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 4.41 2468.1 - 1.03E+07 - - - 474.1605 - 4.078 0.678 - 444.8 1 2 1 1.0061 17 0 0 0 5.05E+08 7.71E+10 - - - 9.3713 1 221125_WJC_METTL3_EV_vs_WT_F07.13752.13752.3 7.55E-11 24/64 R.VEAAQETVADYQQTIK[136.11]K[136.11].Y "sp|Q14203|DCTN1_HUMAN,tr|A0A804CDA6|A0A804CDA6_HUMAN,tr|E7EX90|E7EX90_HUMAN,tr|A0A7P0Z4C3|A0A7P0Z4C3_HUMAN,tr|Q6AWB1|Q6AWB1_HUMAN" 5 1937.0077 1.63 100926 13752 3 1937.005447 646.6765 Dynactin subunit 1 OS=Homo sapiens OX=9606 GN=DCTN1 PE=1 SV=3 4.68 2468.6 - 3.03E+06 - - - -1.1487 - 4.161 0.539 - 763.8 1 2 0 -0.0022 17 0 0 0 2.41E+08 1.48E+08 - - - 8.1506 1 221125_WJC_METTL3_EV_vs_WT_F07.13758.13758.3 2.28E-09 19/56 K.KAEAGAGSATEFQFR.G "sp|Q9NQ39|RS10L_HUMAN,sp|P46783|RS10_HUMAN" 2 1568.7583 1.34 100928 13758 3 1568.75669 523.9267 Putative 40S ribosomal protein S10-like OS=Homo sapiens OX=9606 GN=RPS10P5 PE=5 SV=1 6.14 2469.4 - 4.45E+06 - - - -1.039 - 3.323 0.619 - 551.4 1 2 0 -0.0016 15 0 0 0 3.48E+08 2.61E+08 - - - 8.5743 1 221125_WJC_METTL3_EV_vs_WT_F07.13763.13763.2 7.72E-10 19/40 K.SPAVATSTAAPPPPSSPLPSK[136.11].S "sp|Q14157|UBP2L_HUMAN,tr|F8W726|F8W726_HUMAN" 2 1967.0455 2.81 100929 13763 2 1967.047361 984.53 Ubiquitin-associated protein 2-like OS=Homo sapiens OX=9606 GN=UBAP2L PE=1 SV=2 8.47 2470.1 - 5.65E+06 - - - 0.9425 - 3.995 0.598 - 532 1 2 0 0.0019 21 0 0 0 9.08E+08 3.23E+08 - - - 6.8624 1 221125_WJC_METTL3_EV_vs_WT_F07.13782.13782.4 9.39E-11 26/108 R.ALVDHENVISC[160.03]PHLGASTK.E "sp|O43175|SERA_HUMAN,tr|A0A286YF78|A0A286YF78_HUMAN,tr|A0A2C9F2M7|A0A2C9F2M7_HUMAN,tr|A0A286YF22|A0A286YF22_HUMAN,tr|A0A286YFL2|A0A286YFL2_HUMAN,tr|A0A286YFA2|A0A286YFA2_HUMAN" 6 2047.0157 1.47 100938 13782 4 2047.012847 512.7612 D-3-phosphoglycerate dehydrogenase OS=Homo sapiens OX=9606 GN=PHGDH PE=1 SV=4 5.99 2472.3 - 1.22E+07 - - - -1.381 - 4.26 0.638 - 496.5 1 2 0 -0.0028 19 0 0 0 3.21E+08 2.19E+08 - - - 5.2686 1 221125_WJC_METTL3_EV_vs_WT_F07.13784.13784.4 4.19E-10 26/108 R.ALVDHENVISC[160.03]PHLGASTK[136.11].E "sp|O43175|SERA_HUMAN,tr|A0A286YF78|A0A286YF78_HUMAN,tr|A0A2C9F2M7|A0A2C9F2M7_HUMAN,tr|A0A286YF22|A0A286YF22_HUMAN,tr|A0A286YFL2|A0A286YFL2_HUMAN,tr|A0A286YFA2|A0A286YFA2_HUMAN" 6 2055.0299 1.47 100940 13784 4 2055.026339 514.7647 D-3-phosphoglycerate dehydrogenase OS=Homo sapiens OX=9606 GN=PHGDH PE=1 SV=4 5.99 2472.5 - 8.18E+06 - - - -1.7202 - 4.046 0.583 - 471.1 1 2 0 -0.0035 19 0 0 0 3.21E+08 2.19E+08 - - - 4.7723 1 221125_WJC_METTL3_EV_vs_WT_F07.13787.13787.3 9.96E-10 23/72 R.ALVDHENVISC[160.03]PHLGASTK.E "sp|O43175|SERA_HUMAN,tr|A0A286YF78|A0A286YF78_HUMAN,tr|A0A2C9F2M7|A0A2C9F2M7_HUMAN,tr|A0A286YF22|A0A286YF22_HUMAN,tr|A0A286YFL2|A0A286YFL2_HUMAN,tr|A0A286YFA2|A0A286YFA2_HUMAN" 6 2047.0157 1.48 100941 13787 3 2047.013755 683.3458 D-3-phosphoglycerate dehydrogenase OS=Homo sapiens OX=9606 GN=PHGDH PE=1 SV=4 5.99 2472.9 - 5.23E+06 - - - -0.9375 - 4.626 0.697 - 835.5 1 2 0 -0.0019 19 0 0 0 1.40E+08 9.47E+07 - - - 10.0734 1 221125_WJC_METTL3_EV_vs_WT_F07.13789.13789.3 1.52E-11 26/72 R.ALVDHENVISC[160.03]PHLGASTK[136.11].E "sp|O43175|SERA_HUMAN,tr|A0A286YF78|A0A286YF78_HUMAN,tr|A0A2C9F2M7|A0A2C9F2M7_HUMAN,tr|A0A286YF22|A0A286YF22_HUMAN,tr|A0A286YFL2|A0A286YFL2_HUMAN,tr|A0A286YFA2|A0A286YFA2_HUMAN" 6 2055.0299 1.48 100942 13789 3 2055.024913 686.0172 D-3-phosphoglycerate dehydrogenase OS=Homo sapiens OX=9606 GN=PHGDH PE=1 SV=4 5.99 2473.1 - 4.79E+06 - - - -2.4141 - 4.581 0.591 - 1010 1 2 0 -0.005 19 0 0 0 1.40E+08 9.47E+07 - - - 8.8667 1 221125_WJC_METTL3_EV_vs_WT_F07.13794.13794.2 5.10E-22 30/48 R.NMGGPYGGGNYGPGGSGGSGGYGGR[166.11].S "sp|P22626|ROA2_HUMAN,tr|A0A024RA28|A0A024RA28_HUMAN,tr|A0A7I2V4N1|A0A7I2V4N1_HUMAN,tr|A0A7I2V4I6|A0A7I2V4I6_HUMAN,tr|A0A7I2V323|A0A7I2V323_HUMAN,tr|A0A7I2V3P1|A0A7I2V3P1_HUMAN" 6 2198.9063 1.09 100945 13794 2 2198.899438 1100.4605 Heterogeneous nuclear ribonucleoproteins A2\B1 OS=Homo sapiens OX=9606 GN=HNRNPA2B1 PE=1 SV=2 8.5 2473.6 - 2.33E+06 - - - -3.1425 - 5.139 0.826 - 2025 1 2 0 -0.0069 25 0 0 0 8.70E+07 7.95E+07 - - - 9.164 1 221125_WJC_METTL3_EV_vs_WT_F07.13798.13798.3 1.12E-09 25/80 R.LPLSTPSPGNGSQGSHPLVSR.T sp|Q6ZU65|UBN2_HUMAN 1 2087.076 2.15 100947 13798 3 2087.079882 696.6993 Ubinuclein-2 OS=Homo sapiens OX=9606 GN=UBN2 PE=1 SV=2 9.76 2474.1 - 2.55E+06 - - - 1.8763 - 4.027 0.604 - 603.6 1 2 0 0.0039 21 0 0 0 9.79E+07 4.54E+07 - - - 8.6126 0.9999 221125_WJC_METTL3_EV_vs_WT_F07.13799.13799.3 9.11E-10 22/56 R.LQAQQDAVNIVC[160.03]HSK.T "sp|P55036|PSMD4_HUMAN,tr|A6PVX3|A6PVX3_HUMAN,tr|Q5VWC4|Q5VWC4_HUMAN" 3 1709.8519 1.16 100948 13799 3 1709.85784 570.9579 26S proteasome non-ATPase regulatory subunit 4 OS=Homo sapiens OX=9606 GN=PSMD4 PE=1 SV=1 6.73 2474.1 - 2.95E+06 - - - 3.4722 - 3.751 0.576 - 1007.7 1 2 0 0.0059 15 0 0 0 2.81E+08 2.43E+08 - - - 8.4098 1 221125_WJC_METTL3_EV_vs_WT_F07.13801.13801.3 2.84E-08 15/56 R.LQAQQDAVNIVC[160.03]HSK[136.11].T "sp|P55036|PSMD4_HUMAN,tr|A6PVX3|A6PVX3_HUMAN,tr|Q5VWC4|Q5VWC4_HUMAN" 3 1717.8661 1.16 100950 13801 3 1717.865399 573.6293 26S proteasome non-ATPase regulatory subunit 4 OS=Homo sapiens OX=9606 GN=PSMD4 PE=1 SV=1 6.73 2474.2 - 3.29E+06 - - - -0.4098 - 3.236 0.463 - 493.9 1 2 0 -0.0007 15 0 0 0 2.82E+08 2.43E+08 - - - 6.7661 1 221125_WJC_METTL3_EV_vs_WT_F07.13805.13805.3 1.21E-09 23/96 R.NMGGPYGGGNYGPGGSGGSGGYGGR[166.11].S "sp|P22626|ROA2_HUMAN,tr|A0A024RA28|A0A024RA28_HUMAN,tr|A0A7I2V4N1|A0A7I2V4N1_HUMAN,tr|A0A7I2V4I6|A0A7I2V4I6_HUMAN,tr|A0A7I2V323|A0A7I2V323_HUMAN,tr|A0A7I2V3P1|A0A7I2V3P1_HUMAN" 6 2198.9063 1.13 100952 13805 3 2198.907652 733.9761 Heterogeneous nuclear ribonucleoproteins A2\B1 OS=Homo sapiens OX=9606 GN=HNRNPA2B1 PE=1 SV=2 8.5 2474.8 - 5.55E+06 - - - 0.593 - 4.152 0.614 - 585.8 1 2 0 0.0013 25 0 0 0 2.09E+08 1.85E+08 - - - 8.6603 0.9998 221125_WJC_METTL3_EV_vs_WT_F07.13807.13807.3 4.31E-08 15/52 K.HEK[136.11]EDGAISTIVLR[166.11].G sp|P50990|TCPQ_HUMAN 1 1584.859 0.36 100954 13807 3 1584.854425 529.2936 T-complex protein 1 subunit theta OS=Homo sapiens OX=9606 GN=CCT8 PE=1 SV=4 5.45 2474.9 - 4.50E+06 - - - -2.9119 - 2.878 0.593 - 285.7 1 2 1 -0.0046 14 0 0 0 1.45E+08 4.00E+08 - - - 7.9594 1 221125_WJC_METTL3_EV_vs_WT_F07.13808.13808.3 0.00237 20/60 K.LHVGNISPTC[160.03]TNQELR.A "sp|Q9BQ04|RBM4B_HUMAN,tr|E9PM61|E9PM61_HUMAN,tr|U3KQD5|U3KQD5_HUMAN,tr|E9PLB0|E9PLB0_HUMAN" 4 1837.9105 1.32 100955 13808 3 1837.907898 613.6441 RNA-binding protein 4B OS=Homo sapiens OX=9606 GN=RBM4B PE=1 SV=1 6.74 2475 - 2.73E+06 - - - -1.4054 - 3.677 0.559 - 759.8 1 2 0 -0.0026 16 0 0 0 6.13E+07 4.66E+07 - - - 8.1126 1 221125_WJC_METTL3_EV_vs_WT_F07.13813.13813.3 5.62E-09 18/60 K.LHVGNISPTC[160.03]TNQELR[166.11].A "sp|Q9BQ04|RBM4B_HUMAN,tr|E9PM61|E9PM61_HUMAN,tr|U3KQD5|U3KQD5_HUMAN,tr|E9PLB0|E9PLB0_HUMAN" 4 1847.9188 1.3 100958 13813 3 1847.914832 616.9802 RNA-binding protein 4B OS=Homo sapiens OX=9606 GN=RBM4B PE=1 SV=1 6.74 2475.6 - 3.25E+06 - - - -2.1208 - 3.611 0.562 - 574.9 1 2 0 -0.0039 16 0 0 0 6.27E+07 4.84E+07 - - - 8.0992 0.9999 221125_WJC_METTL3_EV_vs_WT_F07.13815.13815.3 6.16E-06 17/56 R.NGETVPIDEQFDKEK.A sp|P33176|KINH_HUMAN 1 1747.8265 1.65 100960 13815 3 1747.823935 583.6161 Kinesin-1 heavy chain OS=Homo sapiens OX=9606 GN=KIF5B PE=1 SV=1 4.18 2475.9 - 1.80E+06 - - - -1.4441 - 3.106 0.527 - 428.2 1 2 1 -0.0025 15 0 0 0 2.54E+07 1.54E+07 - - - 7.3721 1 221125_WJC_METTL3_EV_vs_WT_F07.13816.13816.3 5.81E-06 18/48 R.IQFKPDDGISPER.A sp|Q96I24|FUBP3_HUMAN 1 1500.7573 1.46 100961 13816 3 1500.755582 501.2597 Far upstream element-binding protein 3 OS=Homo sapiens OX=9606 GN=FUBP3 PE=1 SV=2 4.56 2476 - 1.69E+06 - - - -1.1161 - 3.062 0.45 - 424.1 1 2 0 -0.0017 13 0 0 0 5.44E+07 3.73E+07 - - - 6.5907 1 221125_WJC_METTL3_EV_vs_WT_F07.13820.13820.3 2.45E-11 27/72 K.VVNVANVGAVPSGQDNIHR.F "sp|O00203|AP3B1_HUMAN,tr|H0YBD0|H0YBD0_HUMAN" 2 1945.013 0.85 100963 13820 3 1945.009219 649.3449 AP-3 complex subunit beta-1 OS=Homo sapiens OX=9606 GN=AP3B1 PE=1 SV=3 6.71 2476.5 - 2.37E+06 - - - -1.9296 - 4.092 0.632 - 649.1 1 2 0 -0.0038 19 0 0 0 4.84E+07 5.69E+07 - - - 9.0469 1 221125_WJC_METTL3_EV_vs_WT_F07.13828.13828.2 4.95E-13 16/32 R.AQVQEFC[160.03]DYGTK[136.11]EEC[160.03]MK[136.11].A "sp|Q86U44|MTA70_HUMAN,tr|H0YFV6|H0YFV6_HUMAN" 2 2137.909 0 100969 13828 2 2137.905727 1069.9618 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 4.41 2477.6 - 7.70E+06 - - - -1.5136 - 3.633 0.748 - 599.7 1 2 1 -0.0032 17 0 0 0 7.03E+06 8.00E+09 - - - 7.7364 1 221125_WJC_METTL3_EV_vs_WT_F07.13829.13829.2 3.03E-14 28/48 R.NMGGPYGGGNYGPGGSGGSGGYGGR.S "sp|P22626|ROA2_HUMAN,tr|A0A024RA28|A0A024RA28_HUMAN,tr|A0A7I2V4N1|A0A7I2V4N1_HUMAN,tr|A0A7I2V4I6|A0A7I2V4I6_HUMAN,tr|A0A7I2V323|A0A7I2V323_HUMAN,tr|A0A7I2V3P1|A0A7I2V3P1_HUMAN" 6 2188.8981 1.09 100970 13829 2 2188.897115 1095.4563 Heterogeneous nuclear ribonucleoproteins A2\B1 OS=Homo sapiens OX=9606 GN=HNRNPA2B1 PE=1 SV=2 8.5 2477.7 - 3.63E+06 - - - -0.4399 - 5.092 0.82 - 1725.6 1 2 0 -0.001 25 0 0 0 8.70E+07 7.95E+07 - - - 9.0989 0.9999 221125_WJC_METTL3_EV_vs_WT_F07.13830.13830.3 2.25E-07 15/52 K.HEKEDGAISTIVLR.G sp|P50990|TCPQ_HUMAN 1 1566.8366 0.36 100971 13830 3 1566.835405 523.2861 T-complex protein 1 subunit theta OS=Homo sapiens OX=9606 GN=CCT8 PE=1 SV=4 5.45 2477.7 - 4.93E+06 - - - -0.7435 - 2.637 0.577 - 317.1 1 2 1 -0.0012 14 0 0 0 1.46E+08 4.00E+08 - - - 7.5495 0.9997 221125_WJC_METTL3_EV_vs_WT_F07.13834.13834.3 1.58E-07 15/56 R.NGETVPIDEQFDK[136.11]EK[136.11].A sp|P33176|KINH_HUMAN 1 1763.8549 1.62 100975 13834 3 1763.852647 588.9589 Kinesin-1 heavy chain OS=Homo sapiens OX=9606 GN=KIF5B PE=1 SV=1 4.18 2478.2 - 1.29E+06 - - - -1.2541 - 2.695 0.402 - 329 1 2 1 -0.0022 15 0 0 0 2.46E+07 1.52E+07 - - - 5.6082 1 221125_WJC_METTL3_EV_vs_WT_F07.13835.13835.2 4.54E-05 16/28 R.LQAQQDAVNIVC[160.03]HSK[136.11].T "sp|P55036|PSMD4_HUMAN,tr|A6PVX3|A6PVX3_HUMAN,tr|Q5VWC4|Q5VWC4_HUMAN" 3 1717.8661 1.18 100976 13835 2 1717.864755 859.9403 26S proteasome non-ATPase regulatory subunit 4 OS=Homo sapiens OX=9606 GN=PSMD4 PE=1 SV=1 6.73 2478.3 - 595443 - - - -0.7847 - 3.023 0.608 - 913.8 1 2 0 -0.0013 15 0 0 0 1.08E+07 9.19E+06 - - - 6.251 1 221125_WJC_METTL3_EV_vs_WT_F07.13839.13839.3 0.149 23/96 R.NMGGPYGGGNYGPGGSGGSGGYGGR.S "sp|P22626|ROA2_HUMAN,tr|A0A024RA28|A0A024RA28_HUMAN,tr|A0A7I2V4N1|A0A7I2V4N1_HUMAN,tr|A0A7I2V4I6|A0A7I2V4I6_HUMAN,tr|A0A7I2V323|A0A7I2V323_HUMAN,tr|A0A7I2V3P1|A0A7I2V3P1_HUMAN" 6 2188.8981 1.13 100978 13839 3 2188.898038 730.64 Heterogeneous nuclear ribonucleoproteins A2\B1 OS=Homo sapiens OX=9606 GN=HNRNPA2B1 PE=1 SV=2 8.5 2478.8 - 1.33E+07 - - - -0.0183 - 4.1 0.614 - 587.5 1 2 0 0 25 0 0 0 2.09E+08 1.85E+08 - - - 8.6317 0.9998 221125_WJC_METTL3_EV_vs_WT_F07.13840.13840.4 2.64E-06 16/78 K.HEK[136.11]EDGAISTIVLR[166.11].G sp|P50990|TCPQ_HUMAN 1 1584.859 0.36 100979 13840 4 1584.857458 397.222 T-complex protein 1 subunit theta OS=Homo sapiens OX=9606 GN=CCT8 PE=1 SV=4 5.45 2478.8 - 2.66E+06 - - - -0.9982 - 2.774 0.481 - 157.4 1 2 1 -0.0016 14 0 0 0 1.87E+07 5.18E+07 - - - 3.7835 0.9902 221125_WJC_METTL3_EV_vs_WT_F07.13843.13843.3 0.01 Jul-48 R.IQEDYNDKYWDQR.Y "sp|Q9BSJ2|GCP2_HUMAN,tr|A0A804HJH7|A0A804HJH7_HUMAN,tr|F2Z2B9|F2Z2B9_HUMAN,tr|A0A804HK74|A0A804HK74_HUMAN,tr|A0A804HL95|A0A804HL95_HUMAN,tr|A0A804HJ08|A0A804HJ08_HUMAN,tr|A0A804HJQ4|A0A804HJQ4_HUMAN,tr|A0A804HJS9|A0A804HJS9_HUMAN,tr|A0A804HI27|A0A804HI27_HUMAN" 9 1771.7802 2.62 100982 13843 3 1771.783017 591.6007 Gamma-tubulin complex component 2 OS=Homo sapiens OX=9606 GN=TUBGCP2 PE=1 SV=2 4.23 2479.2 - 426144 - - - 1.6023 - 1.594 0.293 - 78.7 1 2 1 0.0028 13 0 0 0 1.06E+07 4.04E+06 - - - 3.07 1 221125_WJC_METTL3_EV_vs_WT_F07.13847.13847.3 1.31E-11 18/72 R.YLTEHPDPNNENIVGYNNK.K sp|Q6P2Q9|PRP8_HUMAN 1 2230.0291 1.97 100984 13847 3 2230.026049 744.3503 Pre-mRNA-processing-splicing factor 8 OS=Homo sapiens OX=9606 GN=PRPF8 PE=1 SV=2 4.65 2479.7 - 1.60E+06 - - - -1.3569 - 3.38 0.688 - 357.3 1 2 0 -0.003 19 0 0 0 3.58E+07 1.82E+07 - - - 9.2018 1 221125_WJC_METTL3_EV_vs_WT_F07.13848.13848.3 1.80E-08 25/80 K.VGVGTC[160.03]GIADK[136.11]PMTQYQDTSK[136.11].Y sp|O75940|SPF30_HUMAN 1 2271.0846 0.78 100985 13848 3 2271.083795 758.0355 Survival of motor neuron-related-splicing factor 30 OS=Homo sapiens OX=9606 GN=SMNDC1 PE=1 SV=1 5.92 2479.8 - 1.52E+06 - - - -0.3624 - 4.614 0.63 - 852.9 1 2 0 -0.0008 21 0 0 0 1.75E+07 2.24E+07 - - - 9.2296 1 221125_WJC_METTL3_EV_vs_WT_F07.13849.13849.4 6.10E-06 18/120 K.SPAVATSTAAPPPPSSPLPSK.S "sp|Q14157|UBP2L_HUMAN,tr|F8W726|F8W726_HUMAN" 2 1959.0313 4.45 100986 13849 4 1959.034939 490.7651 Ubiquitin-associated protein 2-like OS=Homo sapiens OX=9606 GN=UBAP2L PE=1 SV=2 8.47 2480 - 750996 - - - 1.854 - 3.795 0.5 - 225.1 1 2 0 0.0036 21 0 0 0 3.02E+07 6.77E+06 - - - 4.018 0.985 221125_WJC_METTL3_EV_vs_WT_F07.13851.13851.2 0.0286 17/20 A.PPPPSSPLPSK.S "sp|Q14157|UBP2L_HUMAN,tr|F8W726|F8W726_HUMAN" 2 1102.6023 10.35 100988 13851 2 1102.60469 552.3084 Ubiquitin-associated protein 2-like OS=Homo sapiens OX=9606 GN=UBAP2L PE=1 SV=2 9.18 2480.2 - 639361 - - - 2.2039 - 2.633 0.495 - 1207.9 1 1 0 0.0024 11 0 0 0 1.30E+07 1.26E+06 - - - 5.3153 0.9999 221125_WJC_METTL3_EV_vs_WT_F07.13852.13852.3 0.000148 14/52 R.SFEEEFGTASDKER.V "sp|Q9BZJ0|CRNL1_HUMAN,tr|Q5JY65|Q5JY65_HUMAN" 2 1630.7111 1.47 100989 13852 3 1630.708548 544.5776 Crooked neck-like protein 1 OS=Homo sapiens OX=9606 GN=CRNKL1 PE=1 SV=4 4.25 2480.4 - 495924 - - - -1.5619 - 2.809 0.569 - 173.6 1 2 1 -0.0025 14 0 0 0 7.90E+06 5.37E+06 - - - 7.6279 0.9953 221125_WJC_METTL3_EV_vs_WT_F07.13853.13853.2 0.0659 16-Jul K.LSDGVAVLK[136.11].V "sp|P10809|CH60_HUMAN,tr|A0A7I2V2X6|A0A7I2V2X6_HUMAN,tr|A0A7I2YQK6|A0A7I2YQK6_HUMAN,tr|A0A7I2V599|A0A7I2V599_HUMAN" 4 908.5422 1.39 100990 13853 2 908.540981 455.2784 "60 kDa heat shock protein, mitochondrial OS=Homo sapiens OX=9606 GN=HSPD1 PE=1 SV=2" 5.84 2480.5 - 319934 - - - -1.378 - 1.395 0.192 - 76.9 1 2 0 -0.0013 9 0 0 0 1.20E+07 8.70E+06 - - - 1.4218 0.9994 221125_WJC_METTL3_EV_vs_WT_F07.13858.13858.4 0.00031 15/78 K.HEKEDGAISTIVLR.G sp|P50990|TCPQ_HUMAN 1 1566.8366 0.36 100993 13858 4 1566.835045 392.7164 T-complex protein 1 subunit theta OS=Homo sapiens OX=9606 GN=CCT8 PE=1 SV=4 5.45 2481.1 - 1.21E+06 - - - -0.9733 - 2.222 0.398 - 167 1 2 1 -0.0015 14 0 0 0 1.88E+07 5.20E+07 - - - 2.9803 1 221125_WJC_METTL3_EV_vs_WT_F07.13860.13860.3 5.37E-06 21/80 K.VGVGTC[160.03]GIADKPMTQYQDTSK.Y sp|O75940|SPF30_HUMAN 1 2255.0562 0.78 100995 13860 3 2255.057898 752.6927 Survival of motor neuron-related-splicing factor 30 OS=Homo sapiens OX=9606 GN=SMNDC1 PE=1 SV=1 5.92 2481.4 - 1.25E+06 - - - 0.745 - 4.341 0.518 - 465.5 1 2 0 0.0017 21 0 0 0 1.75E+07 2.24E+07 - - - 7.8344 1 221125_WJC_METTL3_EV_vs_WT_F07.13861.13861.3 5.74E-05 15/68 K.ASTPK[136.11]PPGTGPVPSFAEK[136.11].V sp|O94761|RECQ4_HUMAN 1 1782.9487 1.03 100996 13861 3 1782.947188 595.3235 ATP-dependent DNA helicase Q4 OS=Homo sapiens OX=9606 GN=RECQL4 PE=1 SV=2 8.64 2481.5 - 761554 - - - -0.848 - 2.846 0.428 - 176.8 1 2 0 -0.0015 18 0 0 0 1.99E+07 1.94E+07 - - - 5.9158 1 221125_WJC_METTL3_EV_vs_WT_F07.13863.13863.2 0.000114 30-Dec K.SSTGEASENGLEDIDR.L "sp|Q9BQ70|TCF25_HUMAN,tr|H3BTU3|H3BTU3_HUMAN,tr|H3BMJ8|H3BMJ8_HUMAN,tr|Q9H7D3|Q9H7D3_HUMAN,tr|H3BS87|H3BS87_HUMAN,tr|H3BSP8|H3BSP8_HUMAN" 6 1678.7282 1.08 100998 13863 2 1678.724597 840.3714 Transcription factor 25 OS=Homo sapiens OX=9606 GN=TCF25 PE=1 SV=1 3.83 2481.7 - 516999 - - - -2.1475 - 2.944 0.57 - 477.9 1 2 0 -0.0036 16 0 0 0 5.96E+06 5.50E+06 - - - 5.9046 1 221125_WJC_METTL3_EV_vs_WT_F07.13864.13864.2 1.30E-08 15/30 K.SSTGEASENGLEDIDR[166.11].L "sp|Q9BQ70|TCF25_HUMAN,tr|H3BTU3|H3BTU3_HUMAN,tr|H3BMJ8|H3BMJ8_HUMAN,tr|Q9H7D3|Q9H7D3_HUMAN,tr|H3BS87|H3BS87_HUMAN,tr|H3BSP8|H3BSP8_HUMAN" 6 1688.7365 1.08 100999 13864 2 1688.740042 845.3755 Transcription factor 25 OS=Homo sapiens OX=9606 GN=TCF25 PE=1 SV=1 3.83 2481.9 - 486431 - - - 2.114 - 2.951 0.619 - 865 1 2 0 0.0036 16 0 0 0 5.96E+06 5.50E+06 - - - 6.2723 1 221125_WJC_METTL3_EV_vs_WT_F07.13865.13865.3 2.37E-08 17/56 R.KYPSIIVNC[160.03]VEEKPK.E sp|Q9H0D6|XRN2_HUMAN 1 1802.9601 1.65 101000 13865 3 1802.962701 601.994 5'-3' exoribonuclease 2 OS=Homo sapiens OX=9606 GN=XRN2 PE=1 SV=1 8.16 2482 - 485858 - - - 1.4665 - 2.997 0.537 - 273.5 1 2 0 0.0026 15 0 0 0 1.23E+07 7.44E+06 - - - 7.3904 1 221125_WJC_METTL3_EV_vs_WT_F07.13867.13867.2 3.78E-08 Dec-32 K.TTWGDGGENSPC[160.03]NVVSK.Q "sp|O00161|SNP23_HUMAN,tr|H3BP15|H3BP15_HUMAN,tr|H3BM38|H3BM38_HUMAN,tr|H3BQY9|H3BQY9_HUMAN,tr|H3BV99|H3BV99_HUMAN" 5 1806.7843 1.77 101002 13867 2 1806.782495 904.3994 Synaptosomal-associated protein 23 OS=Homo sapiens OX=9606 GN=SNAP23 PE=1 SV=1 4.37 2482.3 - 360461 - - - -0.9863 - 2.65 0.682 - 291.6 1 2 0 -0.0018 17 0 0 0 4.46E+06 2.52E+06 - - - 6.4737 0.9769 221125_WJC_METTL3_EV_vs_WT_F07.13877.13877.3 0.00544 Oct-44 R.QPWSIPVLPDDK.G "sp|Q68DC2|ANKS6_HUMAN,tr|A0A0A0MRS7|A0A0A0MRS7_HUMAN" 2 1393.7242 17.08 101010 13877 3 1393.717489 465.582 Ankyrin repeat and SAM domain-containing protein 6 OS=Homo sapiens OX=9606 GN=ANKS6 PE=1 SV=2 4.21 2483.5 - 496305 - - - -4.7908 - 1.941 0.23 - 172 1 2 0 -0.0067 12 0 0 0 7.25E+07 4.24E+06 - - - 2.9407 0.9952 221125_WJC_METTL3_EV_vs_WT_F07.13878.13878.3 6.29E-05 Oct-48 R.IQEDYNDK[136.11]YWDQR[166.11].Y "sp|Q9BSJ2|GCP2_HUMAN,tr|A0A804HJH7|A0A804HJH7_HUMAN,tr|F2Z2B9|F2Z2B9_HUMAN,tr|A0A804HK74|A0A804HK74_HUMAN,tr|A0A804HL95|A0A804HL95_HUMAN,tr|A0A804HJ08|A0A804HJ08_HUMAN,tr|A0A804HJQ4|A0A804HJQ4_HUMAN,tr|A0A804HJS9|A0A804HJS9_HUMAN,tr|A0A804HI27|A0A804HI27_HUMAN" 9 1789.8026 2.65 101011 13878 3 1789.796359 597.6082 Gamma-tubulin complex component 2 OS=Homo sapiens OX=9606 GN=TUBGCP2 PE=1 SV=2 4.23 2483.6 - 433295 - - - -3.5138 - 1.849 0.394 - 107.3 1 2 1 -0.0063 13 0 0 0 1.07E+07 4.04E+06 - - - 4.5974 1 221125_WJC_METTL3_EV_vs_WT_F07.13879.13879.2 1.58E-07 13/28 R.LQAQQDAVNIVC[160.03]HSK.T "sp|P55036|PSMD4_HUMAN,tr|A6PVX3|A6PVX3_HUMAN,tr|Q5VWC4|Q5VWC4_HUMAN" 3 1709.8519 1.18 101012 13879 2 1709.849226 855.9332 26S proteasome non-ATPase regulatory subunit 4 OS=Homo sapiens OX=9606 GN=PSMD4 PE=1 SV=1 6.73 2483.7 - 402035 - - - -1.5656 - 2.814 0.582 - 635.1 1 2 0 -0.0027 15 0 0 0 1.08E+07 9.19E+06 - - - 5.8824 1 221125_WJC_METTL3_EV_vs_WT_F07.13884.13884.3 0.000221 16/64 R.HGSYGSADYDYGESGFR.H sp|P20930|FILA_HUMAN 1 1866.7445 999 101015 13884 3 1866.743812 623.2555 Filaggrin OS=Homo sapiens OX=9606 GN=FLG PE=1 SV=3 4.54 2484.3 - 1.45E+06 - - - -0.3798 - 3.151 0.66 - 255 1 2 0 -0.0007 17 0 0 0 1.94E+07 0.00E+00 - - - 8.7976 1 221125_WJC_METTL3_EV_vs_WT_F07.13885.13885.3 1.13E-05 20/52 K.HELLSLASSNHLGK.N "sp|O15372|EIF3H_HUMAN,tr|B3KS98|B3KS98_HUMAN,tr|A0A087WZK9|A0A087WZK9_HUMAN,tr|E5RJT0|E5RJT0_HUMAN" 4 1504.7998 1.65 101016 13885 3 1504.800952 502.6072 Eukaryotic translation initiation factor 3 subunit H OS=Homo sapiens OX=9606 GN=EIF3H PE=1 SV=1 6.92 2484.4 - 3.47E+06 - - - 0.7715 - 3.2 0.536 - 704.1 1 2 0 0.0012 14 0 0 0 4.16E+07 2.52E+07 - - - 7.6067 0.9075 221125_WJC_METTL3_EV_vs_WT_F07.13888.13888.3 0.0752 Aug-60 K.TKNGIAGSSLPPPPIK.H sp|Q9Y5A9|YTHD2_HUMAN 1 1575.8984 1.93 101019 13888 3 1575.904394 526.3068 YTH domain-containing family protein 2 OS=Homo sapiens OX=9606 GN=YTHDF2 PE=1 SV=2 10 2484.6 - 856287 - - - 3.7769 - 1.814 0.219 - 77.3 1 2 1 0.006 16 0 0 0 8.83E+06 4.56E+06 - - - 2.508 0.9999 221125_WJC_METTL3_EV_vs_WT_F07.13889.13889.3 0.000145 15/68 K.ASTPKPPGTGPVPSFAEK.V sp|O94761|RECQ4_HUMAN 1 1766.9203 0.96 101020 13889 3 1766.925107 589.9807 ATP-dependent DNA helicase Q4 OS=Homo sapiens OX=9606 GN=RECQL4 PE=1 SV=2 8.64 2484.7 - 855699 - - - 2.7206 - 3.215 0.459 - 171.2 1 2 0 0.0048 18 0 0 0 1.99E+07 2.08E+07 - - - 6.5641 1 221125_WJC_METTL3_EV_vs_WT_F07.13891.13891.3 0.000219 16/48 K.C[160.03]C[160.03]LTYC[160.03]FNK[136.11]PEDK[136.11].- "sp|P62979|RS27A_HUMAN,tr|A0A2R8Y422|A0A2R8Y422_HUMAN" 2 1749.7495 0.79 101022 13891 3 1749.751905 584.2571 Ubiquitin-40S ribosomal protein S27a OS=Homo sapiens OX=9606 GN=RPS27A PE=1 SV=2 6.05 2485 - 703205 - - - 1.3465 - 2.936 0.599 - 394.8 1 2 0 0.0024 13 0 0 0 1.79E+07 2.26E+07 - - - 8.1378 1 221125_WJC_METTL3_EV_vs_WT_F07.13892.13892.3 2.39E-06 18/56 K.IPDTLQDQLNEQQKR.Q "sp|Q86UP3|ZFHX4_HUMAN,tr|A0A494BZV7|A0A494BZV7_HUMAN,tr|E5RI93|E5RI93_HUMAN,tr|E7EVZ1|E7EVZ1_HUMAN" 4 1824.933 4.18 101023 13892 3 1824.934639 609.3183 Zinc finger homeobox protein 4 OS=Homo sapiens OX=9606 GN=ZFHX4 PE=1 SV=1 4.56 2485.1 - 659197 - - - 0.9036 - 3.391 0.51 - 378.3 1 2 0 0.0016 15 0 0 0 1.07E+07 2.55E+06 - - - 7.4119 1 221125_WJC_METTL3_EV_vs_WT_F07.13893.13893.3 8.74E-10 19/64 K.TPGDFSYAYQKPEETTR.S sp|P46821|MAP1B_HUMAN 1 1988.9116 0.75 101024 13893 3 1988.912558 663.9778 Microtubule-associated protein 1B OS=Homo sapiens OX=9606 GN=MAP1B PE=1 SV=2 4.68 2485.2 - 535084 - - - 0.4887 - 3.59 0.605 - 335.2 1 2 0 0.001 17 0 0 0 6.50E+06 8.67E+06 - - - 8.5139 1 221125_WJC_METTL3_EV_vs_WT_F07.13894.13894.3 1.59E-09 17/48 K.C[160.03]C[160.03]LTYC[160.03]FNKPEDK.- "sp|P62979|RS27A_HUMAN,tr|A0A2R8Y422|A0A2R8Y422_HUMAN" 2 1733.7211 0.8 101025 13894 3 1733.722863 578.9143 Ubiquitin-40S ribosomal protein S27a OS=Homo sapiens OX=9606 GN=RPS27A PE=1 SV=2 6.05 2485.3 - 526485 - - - 0.9886 - 3.253 0.676 - 533.1 1 2 0 0.0017 13 0 0 0 1.79E+07 2.24E+07 - - - 9.2744 0.9999 221125_WJC_METTL3_EV_vs_WT_F07.13895.13895.4 1.06E-05 16/84 R.KYPSIIVNC[160.03]VEEKPK.E sp|Q9H0D6|XRN2_HUMAN 1 1802.9601 0.77 101026 13895 4 1802.964798 451.7473 5'-3' exoribonuclease 2 OS=Homo sapiens OX=9606 GN=XRN2 PE=1 SV=1 8.16 2485.5 - 454388 - - - 2.6296 - 3.142 0.511 - 276 1 2 0 0.0047 15 0 0 0 4.03E+06 5.26E+06 - - - 4.0821 1 221125_WJC_METTL3_EV_vs_WT_F07.13901.13901.3 1.32E-07 15/48 R.NREEEWDPEYTPK.S "sp|Q9Y2W1|TR150_HUMAN,tr|A0A3B3ITZ9|A0A3B3ITZ9_HUMAN" 2 1691.7427 4.58 101030 13901 3 1691.744423 564.9215 Thyroid hormone receptor-associated protein 3 OS=Homo sapiens OX=9606 GN=THRAP3 PE=1 SV=2 4.25 2486.3 - 1.37E+06 - - - 1.0007 - 2.691 0.643 - 424.6 1 2 1 0.0017 13 0 0 0 1.91E+08 4.16E+07 - - - 8.3923 1 221125_WJC_METTL3_EV_vs_WT_F07.13905.13905.4 3.26E-09 26/138 R.VGGVGPADTHEPLRPEAEPGELER.E "sp|Q6WCQ1|MPRIP_HUMAN,tr|A0A494BZV2|A0A494BZV2_HUMAN,tr|H0Y2S9|H0Y2S9_HUMAN,tr|J3KSW8|J3KSW8_HUMAN" 4 2511.2354 1.22 101034 13905 4 2511.236973 628.8161 Myosin phosphatase Rho-interacting protein OS=Homo sapiens OX=9606 GN=MPRIP PE=1 SV=3 4.41 2486.8 - 654885 - - - 0.6343 - 3.997 0.564 - 477.4 1 2 0 0.0016 24 0 0 0 5.63E+06 4.61E+06 - - - 4.5793 0.9998 221125_WJC_METTL3_EV_vs_WT_F07.13906.13906.3 2.15E-07 16/64 K.TATPEIVDNK[136.11]DGTVTVR[166.11].Y "sp|O75369|FLNB_HUMAN,tr|E7EN95|E7EN95_HUMAN,tr|A0A804HL72|A0A804HL72_HUMAN" 3 1832.9599 0.85 101035 13906 3 1832.963464 611.9939 Filamin-B OS=Homo sapiens OX=9606 GN=FLNB PE=1 SV=2 4.56 2486.9 - 595277 - - - 1.9569 - 3.291 0.476 - 223.1 1 2 1 0.0036 17 0 0 0 5.62E+06 6.61E+06 - - - 6.8552 0.9999 221125_WJC_METTL3_EV_vs_WT_F07.13910.13910.3 4.48E-07 16/64 K.TATPEIVDNKDGTVTVR.Y "sp|O75369|FLNB_HUMAN,tr|E7EN95|E7EN95_HUMAN,tr|A0A804HL72|A0A804HL72_HUMAN" 3 1814.9374 0.85 101039 13910 3 1814.936941 605.9864 Filamin-B OS=Homo sapiens OX=9606 GN=FLNB PE=1 SV=2 4.56 2487.4 - 360732 - - - -0.2568 - 3.314 0.532 - 296.5 1 2 1 -0.0005 17 0 0 0 5.62E+06 6.61E+06 - - - 7.498 0.9989 221125_WJC_METTL3_EV_vs_WT_F07.13917.13917.4 0.000149 22/90 R.LNSWFQHRPPGAPPER.Y "sp|Q13724|MOGS_HUMAN,tr|A0A3B3IS52|A0A3B3IS52_HUMAN,tr|A0A3B3IRK6|A0A3B3IRK6_HUMAN,tr|A0A3B3IRW2|A0A3B3IRW2_HUMAN" 4 1887.9492 0.82 101045 13917 4 1887.953267 472.9946 Mannosyl-oligosaccharide glucosidase OS=Homo sapiens OX=9606 GN=MOGS PE=1 SV=5 9.61 2488.3 - 353950 - - - 2.1282 - 3.119 0.303 - 414.6 1 2 0 0.004 16 0 0 0 1.42E+07 1.73E+07 - - - 2.2629 1 221125_WJC_METTL3_EV_vs_WT_F07.13919.13919.3 1.97E-08 21/52 K.HELLSLASSNHLGK[136.11].N "sp|O15372|EIF3H_HUMAN,tr|B3KS98|B3KS98_HUMAN,tr|A0A087WZK9|A0A087WZK9_HUMAN,tr|E5RJT0|E5RJT0_HUMAN" 4 1512.814 1.65 101046 13919 3 1512.815395 505.2786 Eukaryotic translation initiation factor 3 subunit H OS=Homo sapiens OX=9606 GN=EIF3H PE=1 SV=1 6.92 2488.5 - 2.49E+06 - - - 0.9281 - 3.415 0.593 - 817.9 1 2 0 0.0014 14 0 0 0 4.16E+07 2.52E+07 - - - 8.4149 1 221125_WJC_METTL3_EV_vs_WT_F07.13923.13923.4 4.01E-09 19/114 R.IMRPDDANVAGNVHGGTILK.M sp|O00154|BACH_HUMAN 1 2077.0739 1.44 101050 13923 4 2077.077174 520.2757 Cytosolic acyl coenzyme A thioester hydrolase OS=Homo sapiens OX=9606 GN=ACOT7 PE=1 SV=3 6.75 2488.9 - 543638 - - - 1.5965 - 3.736 0.477 - 301.1 1 2 0 0.0033 20 0 0 0 5.27E+06 3.66E+06 - - - 3.8175 0.9999 221125_WJC_METTL3_EV_vs_WT_F07.13925.13925.4 5.87E-07 19/90 R.LNSWFQHR[166.11]PPGAPPER[166.11].Y "sp|Q13724|MOGS_HUMAN,tr|A0A3B3IS52|A0A3B3IS52_HUMAN,tr|A0A3B3IRK6|A0A3B3IRK6_HUMAN,tr|A0A3B3IRW2|A0A3B3IRW2_HUMAN" 4 1907.9658 0.82 101052 13925 4 1907.968694 477.9987 Mannosyl-oligosaccharide glucosidase OS=Homo sapiens OX=9606 GN=MOGS PE=1 SV=5 9.61 2489.2 - 485690 - - - 1.5226 - 3.132 0.464 - 369.4 1 2 0 0.0029 16 0 0 0 1.42E+07 1.73E+07 - - - 3.666 0.9999 221125_WJC_METTL3_EV_vs_WT_F07.13926.13926.4 4.63E-06 18/90 K.KDVDAAYMNKVELEAK.V "sp|P13647|K2C5_HUMAN,sp|O95678|K2C75_HUMAN,tr|H0YIN9|H0YIN9_HUMAN" 3 1822.9135 26.89 101053 13926 4 1822.916624 456.7357 "Keratin, type II cytoskeletal 5 OS=Homo sapiens OX=9606 GN=KRT5 PE=1 SV=3" 4.78 2489.3 - 483867 - - - 1.7137 - 3.511 0.53 - 287.7 1 2 1 0.0031 16 0 0 0 5.41E+06 2.01E+05 - - - 4.2807 0.9963 221125_WJC_METTL3_EV_vs_WT_F07.13927.13927.3 0.000666 Nov-60 R.SLVLQNYTRPEGGQSR.N "sp|P10071|GLI3_HUMAN,tr|A0A2R8YGX0|A0A2R8YGX0_HUMAN,tr|A0A7I2V4X9|A0A7I2V4X9_HUMAN" 3 1803.9228 -1 101054 13927 3 1803.911413 602.3149 Transcriptional activator GLI3 OS=Homo sapiens OX=9606 GN=GLI3 PE=1 SV=6 8.46 2489.4 - 437449 - - - -6.2902 - 2.186 0.423 - 139.9 1 2 0 -0.0113 16 0 0 0 0.00E+00 0.00E+00 - - - 5.2596 0.9994 221125_WJC_METTL3_EV_vs_WT_F07.13929.13929.3 7.04E-09 16/52 K.R[166.11]PLLAFAC[160.03]DDK[136.11]DGK[136.11].Y "sp|Q96J01|THOC3_HUMAN,tr|D6REC9|D6REC9_HUMAN" 2 1630.8347 0.89 101056 13929 3 1630.827958 544.6189 THO complex subunit 3 OS=Homo sapiens OX=9606 GN=THOC3 PE=1 SV=1 6.03 2489.7 - 314388 - - - -4.1629 - 2.597 0.574 - 257.5 1 2 1 -0.0068 14 0 0 0 1.03E+07 1.16E+07 - - - 7.4739 0.9999 221125_WJC_METTL3_EV_vs_WT_F07.13938.13938.3 0.00043 13/48 R.SIFQHIQSAQSQR.S "sp|Q9Y2W1|TR150_HUMAN,tr|A0A3B3ITZ9|A0A3B3ITZ9_HUMAN" 2 1528.7746 3.91 101064 13938 3 1528.776923 510.5988 Thyroid hormone receptor-associated protein 3 OS=Homo sapiens OX=9606 GN=THRAP3 PE=1 SV=2 9.49 2490.8 - 846251 - - - 1.494 - 2.284 0.467 - 157.1 1 2 0 0.0023 13 0 0 0 1.05E+08 2.70E+07 - - - 5.9853 0.9686 221125_WJC_METTL3_EV_vs_WT_F07.13939.13939.3 0.00314 Dec-80 R.LLEGEDAHLSSQQASGQSYSS.R sp|P08779|K1C16_HUMAN 1 2192.9822 - 101065 13939 3 2192.987979 732.0013 "Keratin, type I cytoskeletal 16 OS=Homo sapiens OX=9606 GN=KRT16 PE=1 SV=4" 4.13 2490.9 - 826768 - - - 2.6421 - 2.217 0.423 - 74.2 1 1 0 0.0058 21 0 0 0 - - - - - 5.1632 0.9999 221125_WJC_METTL3_EV_vs_WT_F07.13941.13941.2 0.000104 14/26 K.VQALEEANNDLENK.L sp|P35527|K1C9_HUMAN 1 1585.7584 999 101067 13941 2 1585.757798 793.8865 "Keratin, type I cytoskeletal 9 OS=Homo sapiens OX=9606 GN=KRT9 PE=1 SV=3" 4 2491.1 - 504787 - - - -0.367 - 2.755 0.555 - 612.6 1 2 0 -0.0006 14 0 0 0 3.85E+07 0.00E+00 - - - 5.6832 1 221125_WJC_METTL3_EV_vs_WT_F07.13942.13942.2 8.77E-11 18/28 K.QISNLQQSISDAEQR.G sp|P04264|K2C1_HUMAN 1 1715.8438 999 101068 13942 2 1715.845578 858.9292 "Keratin, type II cytoskeletal 1 OS=Homo sapiens OX=9606 GN=KRT1 PE=1 SV=6" 4.37 2491.3 - 472266 - - - 1.0123 - 3.414 0.661 - 1198.8 1 2 0 0.0017 15 0 0 0 7.64E+06 0.00E+00 - - - 6.9414 1 221125_WJC_METTL3_EV_vs_WT_F07.13943.13943.4 4.98E-08 21/96 K.TGTIVVEGHELHDEDIR[166.11].L "sp|P41252|SYIC_HUMAN,tr|A0A804HL54|A0A804HL54_HUMAN,tr|A0A804HIV9|A0A804HIV9_HUMAN,tr|A0A804HJN6|A0A804HJN6_HUMAN,tr|A0A804HHW9|A0A804HHW9_HUMAN,tr|A0A0A0MSX9|A0A0A0MSX9_HUMAN,tr|J3KR24|J3KR24_HUMAN,tr|A0A804HJ36|A0A804HJ36_HUMAN" 8 1928.9467 1 101069 13943 4 1928.949454 483.244 "Isoleucine--tRNA ligase, cytoplasmic OS=Homo sapiens OX=9606 GN=IARS1 PE=1 SV=2" 4.49 2491.4 - 383023 - - - 1.4075 - 3.922 0.52 - 250.1 1 2 0 0.0027 17 0 0 0 9.59E+07 9.60E+07 - - - 4.2258 1 221125_WJC_METTL3_EV_vs_WT_F07.13944.13944.2 5.54E-14 17/32 R.MSGEC[160.03]APNVSVSVSTSH.T sp|P04264|K2C1_HUMAN 1 1747.7505 - 101070 13944 2 1747.753477 874.8825 "Keratin, type II cytoskeletal 1 OS=Homo sapiens OX=9606 GN=KRT1 PE=1 SV=6" 5.22 2491.5 - 380580 - - - 1.6839 - 3.337 0.781 - 757 1 1 0 0.0029 17 0 0 0 - - - - - 7.7713 0.9998 221125_WJC_METTL3_EV_vs_WT_F07.13946.13946.3 4.70E-06 13/48 R.SIFQHIQSAQSQR[166.11].S "sp|Q9Y2W1|TR150_HUMAN,tr|A0A3B3ITZ9|A0A3B3ITZ9_HUMAN" 2 1538.7829 2.5 101072 13946 3 1538.784326 513.9349 Thyroid hormone receptor-associated protein 3 OS=Homo sapiens OX=9606 GN=THRAP3 PE=1 SV=2 9.49 2491.8 - 310698 - - - 0.9209 - 2.313 0.36 - 164.5 1 2 0 0.0014 13 0 0 0 1.46E+07 5.85E+06 - - - 4.8268 1 221125_WJC_METTL3_EV_vs_WT_F07.13947.13947.2 1.69E-12 17/40 R.LLEGEDAHLSSQQASGQSYSS.R sp|P08779|K1C16_HUMAN 1 2192.9822 - 101073 13947 2 2192.984035 1097.4984 "Keratin, type I cytoskeletal 16 OS=Homo sapiens OX=9606 GN=KRT16 PE=1 SV=4" 4.13 2491.9 - 228024 - - - 0.8436 - 3.456 0.72 - 726.8 1 1 0 0.0019 21 0 0 0 - - - - - 7.4072 0.9995 221125_WJC_METTL3_EV_vs_WT_F07.13948.13948.2 2.43E-10 Nov-32 K.TGIEQGSDAGYLC[160.03]ESQK[136.11].F "sp|P40939|ECHA_HUMAN,tr|A0A2R8YG21|A0A2R8YG21_HUMAN,tr|H0YFD6|H0YFD6_HUMAN,tr|A0A2R8Y4F5|A0A2R8Y4F5_HUMAN" 4 1849.8244 -1 101074 13948 2 1849.818002 925.9195 "Trifunctional enzyme subunit alpha, mitochondrial OS=Homo sapiens OX=9606 GN=HADHA PE=1 SV=2" 4.14 2492 - 141819 - - - -3.436 - 2.545 0.562 - 397.1 1 2 0 -0.0064 17 0 0 0 0.00E+00 0.00E+00 - - - 5.4865 0.9687 221125_WJC_METTL3_EV_vs_WT_F07.13950.13950.3 0.0071 Oct-36 K.LSPWIRPDSK.V "sp|O14744|ANM5_HUMAN,tr|C9JSX3|C9JSX3_HUMAN,tr|G3V580|G3V580_HUMAN,tr|G3V2L6|G3V2L6_HUMAN,tr|G3V2X6|G3V2X6_HUMAN,tr|G3V5L5|G3V5L5_HUMAN" 6 1197.6506 1.91 101075 13950 3 1197.653901 400.2241 Protein arginine N-methyltransferase 5 OS=Homo sapiens OX=9606 GN=PRMT5 PE=1 SV=4 8.75 2492.3 - 238238 - - - 2.7504 - 2.023 0.109 - 116.4 1 2 0 0.0033 10 0 0 0 2.42E+06 1.27E+06 - - - 1.812 1 221125_WJC_METTL3_EV_vs_WT_F07.13952.13952.4 1.65E-12 21/96 K.TGTIVVEGHELHDEDIR.L "sp|P41252|SYIC_HUMAN,tr|A0A804HL54|A0A804HL54_HUMAN,tr|A0A804HIV9|A0A804HIV9_HUMAN,tr|A0A804HJN6|A0A804HJN6_HUMAN,tr|A0A804HHW9|A0A804HHW9_HUMAN,tr|A0A0A0MSX9|A0A0A0MSX9_HUMAN,tr|J3KR24|J3KR24_HUMAN,tr|A0A804HJ36|A0A804HJ36_HUMAN" 8 1918.9385 0.99 101076 13952 4 1918.94228 480.7419 "Isoleucine--tRNA ligase, cytoplasmic OS=Homo sapiens OX=9606 GN=IARS1 PE=1 SV=2" 4.49 2492.5 - 1.66E+06 - - - 1.986 - 3.758 0.64 - 301.4 1 2 0 0.0038 17 0 0 0 9.60E+07 9.69E+07 - - - 5.2552 1 221125_WJC_METTL3_EV_vs_WT_F07.13953.13953.3 4.57E-08 14/40 R.NHPSFYVFNHR.G sp|Q8N4V1|EMC5_HUMAN 1 1416.6687 1.27 101077 13953 3 1416.671083 473.2302 ER membrane protein complex subunit 5 OS=Homo sapiens OX=9606 GN=MMGT1 PE=1 SV=1 8.76 2492.6 - 1.06E+06 - - - 1.6701 - 2.621 0.626 - 304.1 1 2 0 0.0024 11 0 0 0 1.43E+07 1.12E+07 - - - 8.2559 0.9891 221125_WJC_METTL3_EV_vs_WT_F07.13958.13958.4 0.0161 15/96 K.ILHSYVPEEIRDGNQVR.V sp|Q96CB9|NSUN4_HUMAN 1 2024.0439 1.04 101082 13958 4 2024.047647 507.0183 5-methylcytosine rRNA methyltransferase NSUN4 OS=Homo sapiens OX=9606 GN=NSUN4 PE=1 SV=2 5.45 2493.1 - 468997 - - - 1.8325 - 2.615 0.255 - 168.5 1 2 1 0.0037 17 0 0 0 1.57E+07 1.52E+07 - - - 1.7782 1 221125_WJC_METTL3_EV_vs_WT_F07.13964.13964.3 4.25E-12 18/64 K.TGTIVVEGHELHDEDIR[166.11].L "sp|P41252|SYIC_HUMAN,tr|A0A804HL54|A0A804HL54_HUMAN,tr|A0A804HIV9|A0A804HIV9_HUMAN,tr|A0A804HJN6|A0A804HJN6_HUMAN,tr|A0A804HHW9|A0A804HHW9_HUMAN,tr|A0A0A0MSX9|A0A0A0MSX9_HUMAN,tr|J3KR24|J3KR24_HUMAN,tr|A0A804HJ36|A0A804HJ36_HUMAN" 8 1928.9467 1.14 101086 13964 3 1928.950955 643.9895 "Isoleucine--tRNA ligase, cytoplasmic OS=Homo sapiens OX=9606 GN=IARS1 PE=1 SV=2" 4.49 2493.9 - 1.32E+06 - - - 2.1856 - 3.825 0.643 - 311.8 1 2 0 0.0042 17 0 0 0 4.31E+07 3.78E+07 - - - 9.0968 0.9997 221125_WJC_METTL3_EV_vs_WT_F07.13965.13965.4 8.70E-08 15/90 K.VNLQNNPGAMEHFHMK[136.11].L "sp|P51572|BAP31_HUMAN,tr|A0A2R8Y5M6|A0A2R8Y5M6_HUMAN,tr|C9JM14|C9JM14_HUMAN,tr|C9J0M4|C9J0M4_HUMAN,tr|C9JQ75|C9JQ75_HUMAN,tr|C9JSP1|C9JSP1_HUMAN,tr|C9JMD7|C9JMD7_HUMAN" 7 1873.8807 1.05 101087 13965 4 1873.88351 469.4775 B-cell receptor-associated protein 31 OS=Homo sapiens OX=9606 GN=BCAP31 PE=1 SV=3 6.89 2494 - 1.06E+06 - - - 1.4958 - 3.142 0.359 - 197.4 1 2 0 0.0028 16 0 0 0 2.63E+07 2.49E+07 - - - 2.7532 0.9999 221125_WJC_METTL3_EV_vs_WT_F07.13967.13967.3 6.24E-07 13/60 K.VNLQNNPGAMEHFHMK[136.11].L "sp|P51572|BAP31_HUMAN,tr|A0A2R8Y5M6|A0A2R8Y5M6_HUMAN,tr|C9JM14|C9JM14_HUMAN,tr|C9J0M4|C9J0M4_HUMAN,tr|C9JQ75|C9JQ75_HUMAN,tr|C9JSP1|C9JSP1_HUMAN,tr|C9JMD7|C9JMD7_HUMAN" 7 1873.8807 1.06 101089 13967 3 1873.88371 625.6342 B-cell receptor-associated protein 31 OS=Homo sapiens OX=9606 GN=BCAP31 PE=1 SV=3 6.89 2494.2 - 578034 - - - 1.6026 - 2.694 0.421 - 216 1 2 0 0.003 16 0 0 0 1.52E+07 1.44E+07 - - - 5.7757 0.9998 221125_WJC_METTL3_EV_vs_WT_F07.13970.13970.4 1.41E-06 Dec-84 K.GVIVDKDFSHPQMPK.K "sp|P48643|TCPE_HUMAN,tr|E9PCA1|E9PCA1_HUMAN,tr|B7ZAR1|B7ZAR1_HUMAN,tr|E7ENZ3|E7ENZ3_HUMAN" 4 1696.8607 0.59 101092 13970 4 1696.862176 425.2224 T-complex protein 1 subunit epsilon OS=Homo sapiens OX=9606 GN=CCT5 PE=1 SV=1 6.75 2494.6 - 378171 - - - 0.8834 - 2.358 0.487 - 65.9 1 2 1 0.0015 15 0 0 0 3.68E+08 6.29E+08 - - - 3.7714 1 221125_WJC_METTL3_EV_vs_WT_F07.13972.13972.3 7.66E-08 22/80 K.SPAVATSTAAPPPPSSPLPSK.S "sp|Q14157|UBP2L_HUMAN,tr|F8W726|F8W726_HUMAN" 2 1959.0313 3.9 101093 13972 3 1959.034746 654.0177 Ubiquitin-associated protein 2-like OS=Homo sapiens OX=9606 GN=UBAP2L PE=1 SV=2 8.47 2494.8 - 2.29E+06 - - - 1.7555 - 4.158 0.597 - 686 1 2 0 0.0034 21 0 0 0 3.43E+07 8.78E+06 - - - 8.6115 0.9065 221125_WJC_METTL3_EV_vs_WT_F07.13977.13977.3 1.2 Aug-64 K.SSTKPAAGGTAPLPPWK.S "sp|Q15942|ZYX_HUMAN,tr|H7C3D3|H7C3D3_HUMAN,tr|H0Y2Y8|H0Y2Y8_HUMAN,tr|H7C3R3|H7C3R3_HUMAN" 4 1664.8886 1.59 101098 13977 3 1664.890195 555.9701 Zyxin OS=Homo sapiens OX=9606 GN=ZYX PE=1 SV=1 10 2495.4 - 424952 - - - 0.9544 - 1.733 0.079 - 54.2 4 2 0 0.0016 17 0 0 0 1.81E+07 1.14E+07 - - - 0.5308 0.9999 221125_WJC_METTL3_EV_vs_WT_F07.13978.13978.3 1.42E-05 15/52 R.GLSQNLFSNSDHQR[166.11].D sp|Q6UVJ0|SAS6_HUMAN 1 1611.7629 1.22 101099 13978 3 1611.767124 538.2616 Spindle assembly abnormal protein 6 homolog OS=Homo sapiens OX=9606 GN=SASS6 PE=1 SV=1 6.74 2495.5 - 325740 - - - 2.6195 - 2.622 0.463 - 232.8 1 2 0 0.0042 14 0 0 0 5.67E+06 4.65E+06 - - - 6.2625 0.9997 221125_WJC_METTL3_EV_vs_WT_F07.13981.13981.3 0.0718 13/44 R.QSVEADINGLRR.V "sp|P13645|K1C10_HUMAN,sp|Q7Z3Y8|K1C27_HUMAN,sp|P13646|K1C13_HUMAN,tr|A0A1B0GVI3|A0A1B0GVI3_HUMAN,tr|K7EMD9|K7EMD9_HUMAN,tr|K7ERE3|K7ERE3_HUMAN" 6 1356.711 1055.94 101100 13981 3 1356.710317 453.2443 "Keratin, type I cytoskeletal 10 OS=Homo sapiens OX=9606 GN=KRT10 PE=1 SV=6" 6.07 2495.9 - 1.61E+06 - - - -0.4857 - 2.113 0.336 - 275 1 2 0 -0.0007 12 0 0 0 5.33E+08 5.05E+05 - - - 4.3595 1 221125_WJC_METTL3_EV_vs_WT_F07.13982.13982.3 0.0081 16/40 K.RLDYITAEIKR.Y sp|O15212|PFD6_HUMAN 1 1376.7776 4.66 101101 13982 3 1376.776537 459.9331 Prefoldin subunit 6 OS=Homo sapiens OX=9606 GN=PFDN6 PE=1 SV=1 8.59 2496 - 1.26E+06 - - - -0.7714 - 2.664 0.417 - 533.9 1 2 0 -0.0011 11 0 0 0 1.71E+07 3.68E+06 - - - 5.9724 1 221125_WJC_METTL3_EV_vs_WT_F07.13984.13984.3 1.93E-10 15/56 R.LQTEAQEDDWYDC[160.03]HR[166.11].E sp|Q9UHI6|DDX20_HUMAN 1 1974.8042 1.03 101103 13984 3 1974.807187 659.2753 Probable ATP-dependent RNA helicase DDX20 OS=Homo sapiens OX=9606 GN=DDX20 PE=1 SV=2 4.1 2496.2 - 1.16E+06 - - - 1.5252 - 3.232 0.698 - 456 1 2 0 0.003 15 0 0 0 1.13E+07 1.10E+07 - - - 9.3822 0.9987 221125_WJC_METTL3_EV_vs_WT_F07.13985.13985.3 0.0279 Dec-52 R.TYSLGSALRPSTSR.S "sp|P08670|VIME_HUMAN,tr|B0YJC4|B0YJC4_HUMAN,tr|A0A1B0GVG8|A0A1B0GVG8_HUMAN,tr|A0A1B0GTT5|A0A1B0GTT5_HUMAN" 4 1494.7791 1.76 101104 13985 3 1494.778849 499.267 Vimentin OS=Homo sapiens OX=9606 GN=VIM PE=1 SV=4 10.83 2496.3 - 999046 - - - -0.1385 - 1.582 0.3 - 150.6 1 2 0 -0.0002 14 0 0 0 3.44E+08 1.96E+08 - - - 3.1036 1 221125_WJC_METTL3_EV_vs_WT_F07.13986.13986.3 9.17E-08 18/72 K.IVSSSDVGHDEYSTQSLVK.K "sp|Q01082|SPTB2_HUMAN,tr|A0A087WUZ3|A0A087WUZ3_HUMAN" 2 2049.9855 1.28 101105 13986 3 2049.990471 684.3358 "Spectrin beta chain, non-erythrocytic 1 OS=Homo sapiens OX=9606 GN=SPTBN1 PE=1 SV=2" 4.54 2496.4 - 910152 - - - 2.4351 - 2.972 0.568 - 264.3 1 2 0 0.005 19 0 0 0 1.15E+07 9.05E+06 - - - 7.5473 0.9999 221125_WJC_METTL3_EV_vs_WT_F07.13987.13987.3 2.67E-06 13/60 K.VNLQNNPGAMEHFHMK.L "sp|P51572|BAP31_HUMAN,tr|A0A2R8Y5M6|A0A2R8Y5M6_HUMAN,tr|C9JM14|C9JM14_HUMAN,tr|C9J0M4|C9J0M4_HUMAN,tr|C9JQ75|C9JQ75_HUMAN,tr|C9JSP1|C9JSP1_HUMAN,tr|C9JMD7|C9JMD7_HUMAN" 7 1865.8665 1.06 101106 13987 3 1865.864235 622.9628 B-cell receptor-associated protein 31 OS=Homo sapiens OX=9606 GN=BCAP31 PE=1 SV=3 6.89 2496.5 - 871642 - - - -1.2177 - 2.458 0.418 - 210.8 1 2 0 -0.0023 16 0 0 0 1.52E+07 1.44E+07 - - - 5.5073 1 221125_WJC_METTL3_EV_vs_WT_F07.13993.13993.2 6.94E-06 17/40 K.SPAVATSTAAPPPPSSPLPSK.S "sp|Q14157|UBP2L_HUMAN,tr|F8W726|F8W726_HUMAN" 2 1959.0313 5.84 101110 13993 2 1959.032544 980.5229 Ubiquitin-associated protein 2-like OS=Homo sapiens OX=9606 GN=UBAP2L PE=1 SV=2 8.47 2497.2 - 416082 - - - 0.6314 - 3.815 0.637 - 452.2 1 2 0 0.0012 21 0 0 0 1.21E+07 2.07E+06 - - - 7.0373 0.9997 221125_WJC_METTL3_EV_vs_WT_F07.13996.13996.3 0.000407 Dec-56 K.GVIVDK[136.11]DFSHPQMPK[136.11].K "sp|P48643|TCPE_HUMAN,tr|E9PCA1|E9PCA1_HUMAN,tr|B7ZAR1|B7ZAR1_HUMAN,tr|E7ENZ3|E7ENZ3_HUMAN" 4 1712.8891 0.61 101112 13996 3 1712.887402 571.9703 T-complex protein 1 subunit epsilon OS=Homo sapiens OX=9606 GN=CCT5 PE=1 SV=1 6.75 2497.5 - 1.68E+06 - - - -0.9779 - 2.439 0.442 - 163.2 1 2 1 -0.0017 15 0 0 0 2.65E+08 4.35E+08 - - - 5.7939 1 221125_WJC_METTL3_EV_vs_WT_F07.13997.13997.3 1.66E-07 20/60 R.EANFTVSSMHGDMPQK.E "sp|P38919|IF4A3_HUMAN,tr|I3L3H2|I3L3H2_HUMAN" 2 1777.7764 1.64 101113 13997 3 1777.775557 593.5994 Eukaryotic initiation factor 4A-III OS=Homo sapiens OX=9606 GN=EIF4A3 PE=1 SV=4 5.32 2497.6 - 1.93E+06 - - - -0.4489 - 3.83 0.589 - 674.9 1 2 0 -0.0008 16 0 0 0 1.20E+08 7.31E+07 - - - 8.5522 0.9972 221125_WJC_METTL3_EV_vs_WT_F07.13998.13998.4 0.0199 13/96 K.ILHSYVPEEIR[166.11]DGNQVR[166.11].V sp|Q96CB9|NSUN4_HUMAN 1 2044.0605 1.04 101114 13998 4 2044.061138 512.0224 5-methylcytosine rRNA methyltransferase NSUN4 OS=Homo sapiens OX=9606 GN=NSUN4 PE=1 SV=2 5.45 2497.7 - 1.31E+06 - - - 0.3229 - 2.164 0.312 - 119.7 1 2 1 0.0007 17 0 0 0 1.57E+07 1.52E+07 - - - 2.2095 1 221125_WJC_METTL3_EV_vs_WT_F07.14006.14006.3 5.96E-10 18/64 R.AQVQEFC[160.03]DYGTK[136.11]EEC[160.03]MK[136.11].A "sp|Q86U44|MTA70_HUMAN,tr|H0YFV6|H0YFV6_HUMAN" 2 2137.909 0.05 101120 14006 3 2137.904241 713.6436 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 4.41 2498.6 - 4.38E+06 - - - -2.2087 - 3.84 0.683 - 312.4 1 2 1 -0.0047 17 0 0 0 4.04E+06 8.95E+07 - - - 9.5525 1 221125_WJC_METTL3_EV_vs_WT_F07.14007.14007.3 0.000112 19/60 R.EANFTVSSMHGDMPQK[136.11].E "sp|P38919|IF4A3_HUMAN,tr|I3L3H2|I3L3H2_HUMAN" 2 1785.7906 1.64 101121 14007 3 1785.78954 596.2708 Eukaryotic initiation factor 4A-III OS=Homo sapiens OX=9606 GN=EIF4A3 PE=1 SV=4 5.32 2498.6 - 2.61E+06 - - - -0.5684 - 3.242 0.581 - 679.1 1 2 0 -0.001 16 0 0 0 1.20E+08 7.31E+07 - - - 8.0352 1 221125_WJC_METTL3_EV_vs_WT_F07.14008.14008.3 2.21E-07 19/76 R.ELATNLNVGTSSSAASSLKK.Q "sp|O14497|ARI1A_HUMAN,sp|Q8NFD5|ARI1B_HUMAN,tr|A0A3F2YNW7|A0A3F2YNW7_HUMAN,tr|A0A1B0GTJ8|A0A1B0GTJ8_HUMAN,tr|H0Y2R3|H0Y2R3_HUMAN,tr|H0Y3S9|H0Y3S9_HUMAN,tr|H0Y488|H0Y488_HUMAN,tr|A0A6Q8NVI4|A0A6Q8NVI4_HUMAN,tr|A0A1B0GTU5|A0A1B0GTU5_HUMAN,tr|A0A1B0GVK1|A0A1B0GVK1_HUMAN,tr|H0Y7H8|H0Y7H8_HUMAN,tr|A0A087WUV6|A0A087WUV6_HUMAN,tr|A0A1B0GV63|A0A1B0GV63_HUMAN,tr|A0A1B0GWJ2|A0A1B0GWJ2_HUMAN" 14 1977.0378 1.37 101122 14008 3 1977.039572 660.0199 AT-rich interactive domain-containing protein 1A OS=Homo sapiens OX=9606 GN=ARID1A PE=1 SV=3 8.69 2498.8 - 1.09E+06 - - - 0.8715 - 3.715 0.574 - 372.5 1 2 0 0.0017 20 0 0 0 1.17E+07 8.53E+06 - - - 8.1229 1 221125_WJC_METTL3_EV_vs_WT_F07.14010.14010.3 0.0221 20/76 R.ELATNLNVGTSSSAASSLK[136.11]K[136.11].Q "sp|O14497|ARI1A_HUMAN,sp|Q8NFD5|ARI1B_HUMAN,tr|A0A3F2YNW7|A0A3F2YNW7_HUMAN,tr|A0A1B0GTJ8|A0A1B0GTJ8_HUMAN,tr|H0Y2R3|H0Y2R3_HUMAN,tr|H0Y3S9|H0Y3S9_HUMAN,tr|H0Y488|H0Y488_HUMAN,tr|A0A6Q8NVI4|A0A6Q8NVI4_HUMAN,tr|A0A1B0GTU5|A0A1B0GTU5_HUMAN,tr|A0A1B0GVK1|A0A1B0GVK1_HUMAN,tr|H0Y7H8|H0Y7H8_HUMAN,tr|A0A087WUV6|A0A087WUV6_HUMAN,tr|A0A1B0GV63|A0A1B0GV63_HUMAN,tr|A0A1B0GWJ2|A0A1B0GWJ2_HUMAN" 14 1993.0662 1.37 101124 14010 3 1993.067551 665.3627 AT-rich interactive domain-containing protein 1A OS=Homo sapiens OX=9606 GN=ARID1A PE=1 SV=3 8.69 2499 - 632191 - - - 0.6533 - 3.562 0.462 - 373 1 2 0 0.0013 20 0 0 0 1.17E+07 8.53E+06 - - - 6.7723 0.9998 221125_WJC_METTL3_EV_vs_WT_F07.14015.14015.3 0.000116 14/52 K.GKPIFEVNKQDIYK.S "sp|Q6P3W7|SCYL2_HUMAN,tr|F8VSC5|F8VSC5_HUMAN,tr|A0A0U1RQQ9|A0A0U1RQQ9_HUMAN" 3 1677.909 2.8 101127 14015 3 1677.906828 560.3103 SCY1-like protein 2 OS=Homo sapiens OX=9606 GN=SCYL2 PE=1 SV=1 8.43 2499.7 - 2.48E+06 - - - -1.2986 - 2.929 0.443 - 141.7 1 2 1 -0.0022 14 0 0 0 6.15E+07 2.20E+07 - - - 6.3344 1 221125_WJC_METTL3_EV_vs_WT_F07.14016.14016.3 1.33E-07 24/56 K.GVIVDKDFSHPQMPK.K "sp|P48643|TCPE_HUMAN,tr|E9PCA1|E9PCA1_HUMAN,tr|B7ZAR1|B7ZAR1_HUMAN,tr|E7ENZ3|E7ENZ3_HUMAN" 4 1696.8607 0.61 101128 14016 3 1696.862226 566.6275 T-complex protein 1 subunit epsilon OS=Homo sapiens OX=9606 GN=CCT5 PE=1 SV=1 6.75 2499.8 - 1.13E+06 - - - 0.9129 - 4.157 0.639 - 633.7 1 2 1 0.0015 15 0 0 0 2.65E+08 4.35E+08 - - - 9.3816 1 221125_WJC_METTL3_EV_vs_WT_F07.14017.14017.3 2.25E-07 Dec-48 K.KFMDQHPEMDFSK.A sp|Q9Y266|NUDC_HUMAN 1 1638.717 2.08 101129 14017 3 1638.714158 547.2463 Nuclear migration protein nudC OS=Homo sapiens OX=9606 GN=NUDC PE=1 SV=1 5.38 2499.9 - 917484 - - - -1.7642 - 2.87 0.504 - 154.9 1 2 0 -0.0029 13 0 0 0 7.74E+06 3.72E+06 - - - 7.0168 1 221125_WJC_METTL3_EV_vs_WT_F07.14018.14018.4 4.16E-05 16/90 R.DSDSGLEQMSIGHHIR.D sp|Q15773|MLF2_HUMAN 1 1780.8162 1.09 101130 14018 4 1780.813739 446.2113 Myeloid leukemia factor 2 OS=Homo sapiens OX=9606 GN=MLF2 PE=1 SV=1 5.21 2500.1 - 697929 - - - -1.4078 - 2.076 0.48 - 165.1 1 2 0 -0.0025 16 0 0 0 4.39E+06 4.03E+06 - - - 3.6605 1 221125_WJC_METTL3_EV_vs_WT_F07.14022.14022.3 2.37E-11 19/60 R.SEDLDNSIDKTEAGIK.E sp|Q9UQE7|SMC3_HUMAN 1 1733.8319 0.88 101134 14022 3 1733.826622 578.9513 Structural maintenance of chromosomes protein 3 OS=Homo sapiens OX=9606 GN=SMC3 PE=1 SV=2 4.1 2500.6 - 585747 - - - -3.0666 - 3.934 0.681 - 437 1 2 1 -0.0053 16 0 0 0 6.06E+07 6.86E+07 - - - 9.6454 1 221125_WJC_METTL3_EV_vs_WT_F07.14025.14025.2 3.42E-05 15/36 K.SSELDASDSSSSSNLSLAK[136.11].V "sp|P27448|MARK3_HUMAN,tr|A0A7I2V3C6|A0A7I2V3C6_HUMAN,tr|A0A7I2V3I9|A0A7I2V3I9_HUMAN,tr|A0A7I2V5G3|A0A7I2V5G3_HUMAN,tr|A0A7I2YQF7|A0A7I2YQF7_HUMAN,tr|A0A7I2V4K8|A0A7I2V4K8_HUMAN,tr|A0A7I2V3K2|A0A7I2V3K2_HUMAN,tr|A0A7I2V2U9|A0A7I2V2U9_HUMAN,tr|A0A7I2V4G7|A0A7I2V4G7_HUMAN,tr|H0YNV4|H0YNV4_HUMAN,tr|A0A7I2V2N8|A0A7I2V2N8_HUMAN,tr|A0A7I2V409|A0A7I2V409_HUMAN,tr|A0A7I2V4T2|A0A7I2V4T2_HUMAN,tr|A0A7I2V3B9|A0A7I2V3B9_HUMAN,tr|A0A7I2V639|A0A7I2V639_HUMAN,tr|A0A7I2V2E3|A0A7I2V2E3_HUMAN,tr|A0A7I2V2I9|A0A7I2V2I9_HUMAN,tr|J3KNR0|J3KNR0_HUMAN,tr|H0YKP9|H0YKP9_HUMAN" 19 1891.8738 0.9 101137 14025 2 1891.873802 946.9442 MAP\microtubule affinity-regulating kinase 3 OS=Homo sapiens OX=9606 GN=MARK3 PE=1 SV=5 4.03 2501 - 342281 - - - -0.0042 - 3.547 0.666 - 580.9 1 2 0 0 19 0 0 0 5.31E+06 5.89E+06 - - - 7.0728 0.9999 221125_WJC_METTL3_EV_vs_WT_F07.14026.14026.3 4.95E-06 13/52 K.LLVPAAEGEDSLKK.M "sp|Q96PU8|QKI_HUMAN,tr|F5GYM3|F5GYM3_HUMAN,tr|F5GXS8|F5GXS8_HUMAN,tr|H0YG47|H0YG47_HUMAN,tr|H0YGD6|H0YGD6_HUMAN" 5 1468.8137 0.55 101138 14026 3 1468.813439 490.6118 Protein quaking OS=Homo sapiens OX=9606 GN=QKI PE=1 SV=1 4.68 2501.1 - 264339 - - - -0.1845 - 2.247 0.373 - 232.8 1 2 0 -0.0003 14 0 0 0 3.69E+06 6.74E+06 - - - 4.85 0.9998 221125_WJC_METTL3_EV_vs_WT_F07.14029.14029.2 0.000511 14/22 R.QSVEADINGLRR.V "sp|P13645|K1C10_HUMAN,sp|Q7Z3Y8|K1C27_HUMAN,sp|P13646|K1C13_HUMAN,tr|A0A1B0GVI3|A0A1B0GVI3_HUMAN,tr|K7EMD9|K7EMD9_HUMAN,tr|K7ERE3|K7ERE3_HUMAN" 6 1356.711 999 101139 14029 2 1356.709648 679.3628 "Keratin, type I cytoskeletal 10 OS=Homo sapiens OX=9606 GN=KRT10 PE=1 SV=6" 6.07 2501.5 - 5.00E+06 - - - -0.9788 - 2.154 0.4 - 264.8 1 2 0 -0.0013 12 0 0 0 5.53E+07 0.00E+00 - - - 4.0139 1 221125_WJC_METTL3_EV_vs_WT_F07.14030.14030.3 4.72E-09 17/60 R.SEDLDNSIDK[136.11]TEAGIK[136.11].E sp|Q9UQE7|SMC3_HUMAN 1 1749.8603 0.9 101140 14030 3 1749.857746 584.2941 Structural maintenance of chromosomes protein 3 OS=Homo sapiens OX=9606 GN=SMC3 PE=1 SV=2 4.1 2501.6 - 2.86E+06 - - - -1.4818 - 3.448 0.615 - 312.1 1 2 1 -0.0026 16 0 0 0 5.96E+07 6.66E+07 - - - 8.5719 1 221125_WJC_METTL3_EV_vs_WT_F07.14035.14035.3 7.10E-08 27/72 R.LRGIEQAVQSHAVAEEEAR.K "sp|Q16891|MIC60_HUMAN,tr|B9A067|B9A067_HUMAN,tr|C9J406|C9J406_HUMAN,tr|H7C463|H7C463_HUMAN" 4 2092.0661 1.39 101145 14035 3 2092.068766 698.3627 MICOS complex subunit MIC60 OS=Homo sapiens OX=9606 GN=IMMT PE=1 SV=1 4.91 2502 - 1.41E+06 - - - 1.26 - 4.449 0.607 - 776.4 1 2 1 0.0026 19 0 0 0 5.48E+07 3.93E+07 - - - 8.9739 0.9928 221125_WJC_METTL3_EV_vs_WT_F07.14038.14038.2 0.0895 26-Jun R.TYSLGSALRPSTSR.S "sp|P08670|VIME_HUMAN,tr|B0YJC4|B0YJC4_HUMAN,tr|A0A1B0GVG8|A0A1B0GVG8_HUMAN,tr|A0A1B0GTT5|A0A1B0GTT5_HUMAN" 4 1494.7791 2.02 101148 14038 2 1494.779542 748.3968 Vimentin OS=Homo sapiens OX=9606 GN=VIM PE=1 SV=4 10.83 2502.4 - 733463 - - - 0.3251 - 1.156 0.217 - 25.1 2 2 0 0.0005 14 0 0 0 2.66E+07 1.32E+07 - - - 0.8729 1 221125_WJC_METTL3_EV_vs_WT_F07.14040.14040.2 2.86E-10 14/30 R.EANFTVSSMHGDMPQK.E "sp|P38919|IF4A3_HUMAN,tr|I3L3H2|I3L3H2_HUMAN" 2 1777.7764 1.87 101150 14040 2 1777.773294 889.8955 Eukaryotic initiation factor 4A-III OS=Homo sapiens OX=9606 GN=EIF4A3 PE=1 SV=4 5.32 2502.7 - 289843 - - - -1.7218 - 3.085 0.735 - 567 1 2 0 -0.0031 16 0 0 0 3.46E+06 1.85E+06 - - - 7.2384 1 221125_WJC_METTL3_EV_vs_WT_F07.14042.14042.3 9.69E-07 13/64 K.TGTIVVEGHELHDEDIR.L "sp|P41252|SYIC_HUMAN,tr|A0A804HL54|A0A804HL54_HUMAN,tr|A0A804HIV9|A0A804HIV9_HUMAN,tr|A0A804HJN6|A0A804HJN6_HUMAN,tr|A0A804HHW9|A0A804HHW9_HUMAN,tr|A0A0A0MSX9|A0A0A0MSX9_HUMAN,tr|J3KR24|J3KR24_HUMAN,tr|A0A804HJ36|A0A804HJ36_HUMAN" 8 1918.9385 1.14 101151 14042 3 1918.936159 640.6534 "Isoleucine--tRNA ligase, cytoplasmic OS=Homo sapiens OX=9606 GN=IARS1 PE=1 SV=2" 4.49 2502.9 - 805758 - - - -1.2038 - 3.18 0.475 - 171.8 1 2 0 -0.0023 17 0 0 0 4.26E+07 3.75E+07 - - - 6.7578 0.9994 221125_WJC_METTL3_EV_vs_WT_F07.14044.14044.3 1.90E-08 14/52 K.GK[136.11]PIFEVNK[136.11]QDIYK[136.11].S "sp|Q6P3W7|SCYL2_HUMAN,tr|F8VSC5|F8VSC5_HUMAN,tr|A0A0U1RQQ9|A0A0U1RQQ9_HUMAN" 3 1701.9516 2.55 101152 14044 3 1701.945559 568.3245 SCY1-like protein 2 OS=Homo sapiens OX=9606 GN=SCYL2 PE=1 SV=1 8.43 2503.1 - 2.29E+06 - - - -3.5536 - 2.823 0.491 - 146 1 2 1 -0.006 14 0 0 0 5.60E+07 2.19E+07 - - - 6.7705 0.9933 221125_WJC_METTL3_EV_vs_WT_F07.14046.14046.2 1.38E-07 22-Oct R.R[166.11]AEQDSTTVAAF.A "sp|Q86U44|MTA70_HUMAN,tr|F5H6D8|F5H6D8_HUMAN,tr|H0YFV6|H0YFV6_HUMAN,tr|B4DTN4|B4DTN4_HUMAN" 4 1304.6236 0.06 101154 14046 2 1304.623199 653.3191 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 4.37 2503.3 - 2.30E+06 - - - -0.3181 - 2.138 0.534 - 316.4 1 1 0 -0.0004 12 0 0 0 2.22E+06 3.78E+07 - - - 4.9843 1 221125_WJC_METTL3_EV_vs_WT_F07.14047.14047.3 2.44E-10 29/72 R.LR[166.11]GIEQAVQSHAVAEEEAR[166.11].K "sp|Q16891|MIC60_HUMAN,tr|B9A067|B9A067_HUMAN,tr|C9J406|C9J406_HUMAN,tr|H7C463|H7C463_HUMAN" 4 2112.0827 1.39 101155 14047 3 2112.080594 705.0348 MICOS complex subunit MIC60 OS=Homo sapiens OX=9606 GN=IMMT PE=1 SV=1 4.91 2503.4 - 1.63E+06 - - - -0.9829 - 4.533 0.663 - 1175.7 1 2 1 -0.0021 19 0 0 0 5.48E+07 3.93E+07 - - - 9.6444 0.9996 221125_WJC_METTL3_EV_vs_WT_F07.14048.14048.3 0.000654 15/64 K.IQVLQQQADDAEERAER.L "tr|Q5VU61|Q5VU61_HUMAN,tr|A0A087WWU8|A0A087WWU8_HUMAN,tr|D6R904|D6R904_HUMAN" 3 1997.9766 0.87 101156 14048 3 1997.982512 666.9995 Tropomyosin alpha-3 chain OS=Homo sapiens OX=9606 GN=TPM3 PE=1 SV=3 4.18 2503.5 - 1.23E+06 - - - 2.936 - 3.057 0.493 - 265.4 1 2 1 0.0059 17 0 0 0 1.24E+07 1.43E+07 - - - 6.8578 1 221125_WJC_METTL3_EV_vs_WT_F07.14051.14051.2 6.41E-11 17/36 K.SSELDASDSSSSSNLSLAK.V "sp|P27448|MARK3_HUMAN,tr|A0A7I2V3C6|A0A7I2V3C6_HUMAN,tr|A0A7I2V3I9|A0A7I2V3I9_HUMAN,tr|A0A7I2V5G3|A0A7I2V5G3_HUMAN,tr|A0A7I2YQF7|A0A7I2YQF7_HUMAN,tr|A0A7I2V4K8|A0A7I2V4K8_HUMAN,tr|A0A7I2V3K2|A0A7I2V3K2_HUMAN,tr|A0A7I2V2U9|A0A7I2V2U9_HUMAN,tr|A0A7I2V4G7|A0A7I2V4G7_HUMAN,tr|H0YNV4|H0YNV4_HUMAN,tr|A0A7I2V2N8|A0A7I2V2N8_HUMAN,tr|A0A7I2V409|A0A7I2V409_HUMAN,tr|A0A7I2V4T2|A0A7I2V4T2_HUMAN,tr|A0A7I2V3B9|A0A7I2V3B9_HUMAN,tr|A0A7I2V639|A0A7I2V639_HUMAN,tr|A0A7I2V2E3|A0A7I2V2E3_HUMAN,tr|A0A7I2V2I9|A0A7I2V2I9_HUMAN,tr|J3KNR0|J3KNR0_HUMAN,tr|H0YKP9|H0YKP9_HUMAN" 19 1883.8596 0.9 101159 14051 2 1883.861007 942.9371 MAP\microtubule affinity-regulating kinase 3 OS=Homo sapiens OX=9606 GN=MARK3 PE=1 SV=5 4.03 2503.9 - 497479 - - - 0.7416 - 3.572 0.711 - 849.8 1 2 0 0.0014 19 0 0 0 5.31E+06 5.89E+06 - - - 7.422 1 221125_WJC_METTL3_EV_vs_WT_F07.14053.14053.3 1.45E-05 Dec-56 R.K[136.11]YPSIIVNC[160.03]VEEK[136.11]PK[136.11].E sp|Q9H0D6|XRN2_HUMAN 1 1827.0027 1.25 101161 14053 3 1827.003212 610.0082 5'-3' exoribonuclease 2 OS=Homo sapiens OX=9606 GN=XRN2 PE=1 SV=1 8.16 2504.1 - 359726 - - - 0.3038 - 2.78 0.473 - 151.1 1 2 0 0.0006 15 0 0 0 1.34E+07 1.07E+07 - - - 6.4813 0.9999 221125_WJC_METTL3_EV_vs_WT_F07.14057.14057.4 1.60E-06 18/90 R.DYVPDSYRHPDAFGGR.G sp|Q5JSZ5|PRC2B_HUMAN 1 1850.8336 0.96 101163 14057 4 1850.832772 463.7157 Protein PRRC2B OS=Homo sapiens OX=9606 GN=PRRC2B PE=1 SV=2 5.3 2504.6 - 1.95E+06 - - - -0.4528 - 2.486 0.513 - 239.1 1 2 1 -0.0008 16 0 0 0 2.61E+07 2.72E+07 - - - 4.0117 0.9999 221125_WJC_METTL3_EV_vs_WT_F07.14058.14058.4 3.56E-06 25/108 R.LR[166.11]GIEQAVQSHAVAEEEAR[166.11].K "sp|Q16891|MIC60_HUMAN,tr|B9A067|B9A067_HUMAN,tr|C9J406|C9J406_HUMAN,tr|H7C463|H7C463_HUMAN" 4 2112.0827 1.41 101164 14058 4 2112.082685 529.0279 MICOS complex subunit MIC60 OS=Homo sapiens OX=9606 GN=IMMT PE=1 SV=1 4.91 2504.6 - 2.64E+06 - - - 0.0071 - 4.355 0.596 - 710.7 1 2 1 0 19 0 0 0 5.75E+07 4.07E+07 - - - 4.9113 0.9999 221125_WJC_METTL3_EV_vs_WT_F07.14059.14059.4 7.43E-07 18/90 R.DYVPDSYR[166.11]HPDAFGGR[166.11].G sp|Q5JSZ5|PRC2B_HUMAN 1 1870.8501 0.29 101165 14059 4 1870.850208 468.7198 Protein PRRC2B OS=Homo sapiens OX=9606 GN=PRRC2B PE=1 SV=2 5.3 2504.7 - 1.71E+06 - - - 0.031 - 2.48 0.497 - 231.6 1 2 1 0.0001 16 0 0 0 7.32E+06 2.55E+07 - - - 3.8718 1 221125_WJC_METTL3_EV_vs_WT_F07.14064.14064.3 4.76E-08 20/52 K.NRPFMGSISQQNIR.S "sp|Q9NWS0|PIHD1_HUMAN,tr|M0QXD5|M0QXD5_HUMAN,tr|M0R3A4|M0R3A4_HUMAN,tr|M0R2P8|M0R2P8_HUMAN,tr|M0QYA2|M0QYA2_HUMAN" 5 1646.8311 6.57 101170 14064 3 1646.833127 549.951 PIH1 domain-containing protein 1 OS=Homo sapiens OX=9606 GN=PIH1D1 PE=1 SV=1 12 2505.4 - 546040 - - - 1.226 - 3.201 0.529 - 651.3 1 2 0 0.002 14 0 0 0 2.41E+07 3.66E+06 - - - 7.5292 0.9908 221125_WJC_METTL3_EV_vs_WT_F07.14068.14068.2 2.73E-05 Aug-34 R.MSGEC[160.03]APNVSVSVSTSHT.T sp|P04264|K2C1_HUMAN 1 1848.7982 - 101174 14068 2 1848.800484 925.4064 "Keratin, type II cytoskeletal 1 OS=Homo sapiens OX=9606 GN=KRT1 PE=1 SV=6" 5.22 2505.9 - 310391 - - - 1.2284 - 1.874 0.616 - 140.4 1 1 0 0.0023 18 0 0 0 - - - - - 5.1342 1 221125_WJC_METTL3_EV_vs_WT_F07.14069.14069.2 7.27E-09 14/30 R.SEDLDNSIDK[136.11]TEAGIK[136.11].E sp|Q9UQE7|SMC3_HUMAN 1 1749.8603 0.79 101175 14069 2 1749.862987 875.9374 Structural maintenance of chromosomes protein 3 OS=Homo sapiens OX=9606 GN=SMC3 PE=1 SV=2 4.1 2506 - 299576 - - - 1.5133 - 2.953 0.649 - 571.1 1 2 1 0.0026 16 0 0 0 2.35E+06 2.98E+06 - - - 6.4958 1 221125_WJC_METTL3_EV_vs_WT_F07.14071.14071.2 2.74E-09 15/30 R.SEDLDNSIDKTEAGIK.E sp|Q9UQE7|SMC3_HUMAN 1 1733.8319 0.79 101177 14071 2 1733.829994 867.9232 Structural maintenance of chromosomes protein 3 OS=Homo sapiens OX=9606 GN=SMC3 PE=1 SV=2 4.1 2506.3 - 254003 - - - -1.1218 - 3.141 0.641 - 639.2 1 2 1 -0.0019 16 0 0 0 2.35E+06 2.98E+06 - - - 6.5887 1 221125_WJC_METTL3_EV_vs_WT_F07.14074.14074.4 4.86E-12 24/108 R.LRGIEQAVQSHAVAEEEAR.K "sp|Q16891|MIC60_HUMAN,tr|B9A067|B9A067_HUMAN,tr|C9J406|C9J406_HUMAN,tr|H7C463|H7C463_HUMAN" 4 2092.0661 1.41 101178 14074 4 2092.067003 524.0238 MICOS complex subunit MIC60 OS=Homo sapiens OX=9606 GN=IMMT PE=1 SV=1 4.91 2506.7 - 4.26E+06 - - - 0.4173 - 4.183 0.626 - 685.4 1 2 1 0.0009 19 0 0 0 5.73E+07 4.07E+07 - - - 5.1586 1 221125_WJC_METTL3_EV_vs_WT_F07.14075.14075.3 1.78E-10 20/64 K.RVEAAQETVADYQQTIK.K "sp|Q14203|DCTN1_HUMAN,tr|A0A804CDA6|A0A804CDA6_HUMAN,tr|E7EX90|E7EX90_HUMAN,tr|A0A7P0Z4C3|A0A7P0Z4C3_HUMAN,tr|Q6AWB1|Q6AWB1_HUMAN" 5 1948.9854 2.97 101179 14075 3 1948.983129 650.6691 Dynactin subunit 1 OS=Homo sapiens OX=9606 GN=DCTN1 PE=1 SV=3 4.68 2506.7 - 2.84E+06 - - - -1.1755 - 3.646 0.629 - 681.9 1 2 0 -0.0023 17 0 0 0 8.81E+07 2.96E+07 - - - 8.8202 1 221125_WJC_METTL3_EV_vs_WT_F07.14076.14076.3 2.13E-10 18/64 K.R[166.11]VEAAQETVADYQQTIK[136.11].K "sp|Q14203|DCTN1_HUMAN,tr|A0A804CDA6|A0A804CDA6_HUMAN,tr|E7EX90|E7EX90_HUMAN,tr|A0A7P0Z4C3|A0A7P0Z4C3_HUMAN,tr|Q6AWB1|Q6AWB1_HUMAN" 5 1967.0079 2.96 101180 14076 3 1967.006549 656.6766 Dynactin subunit 1 OS=Homo sapiens OX=9606 GN=DCTN1 PE=1 SV=3 4.68 2506.8 - 1.64E+06 - - - -0.6817 - 3.87 0.574 - 486.3 1 2 0 -0.0013 17 0 0 0 8.77E+07 2.96E+07 - - - 8.3579 0.9998 221125_WJC_METTL3_EV_vs_WT_F07.14078.14078.3 0.00659 15/48 K.SLGDQYVKDEFRR.H "sp|Q9NRP4|SDHF3_HUMAN,tr|F8W9V1|F8W9V1_HUMAN" 2 1611.8005 1.05 101182 14078 3 1611.801971 538.2741 "Succinate dehydrogenase assembly factor 3, mitochondrial OS=Homo sapiens OX=9606 GN=SDHAF3 PE=1 SV=1" 5.84 2506.9 - 1.41E+06 - - - 0.9009 - 2.416 0.461 - 216.4 1 2 1 0.0015 13 0 0 0 1.51E+07 1.44E+07 - - - 6.071 0.9993 221125_WJC_METTL3_EV_vs_WT_F07.14079.14079.4 9.56E-07 18/72 K.SLGDQYVKDEFRR.H "sp|Q9NRP4|SDHF3_HUMAN,tr|F8W9V1|F8W9V1_HUMAN" 2 1611.8005 1.21 101183 14079 4 1611.800446 403.9574 "Succinate dehydrogenase assembly factor 3, mitochondrial OS=Homo sapiens OX=9606 GN=SDHAF3 PE=1 SV=1" 5.84 2507 - 1.40E+06 - - - -0.0453 - 2.977 0.373 - 255.2 1 2 1 -0.0001 13 0 0 0 1.61E+07 1.33E+07 - - - 2.8771 0.9997 221125_WJC_METTL3_EV_vs_WT_F07.14080.14080.4 5.24E-05 19/72 K.SLGDQYVK[136.11]DEFR[166.11]R[166.11].H "sp|Q9NRP4|SDHF3_HUMAN,tr|F8W9V1|F8W9V1_HUMAN" 2 1639.8313 1.21 101184 14080 4 1639.832175 410.9651 "Succinate dehydrogenase assembly factor 3, mitochondrial OS=Homo sapiens OX=9606 GN=SDHAF3 PE=1 SV=1" 5.84 2507.1 - 977205 - - - 0.5586 - 2.523 0.439 - 243.7 1 2 1 0.0009 13 0 0 0 1.69E+07 1.39E+07 - - - 3.3899 1 221125_WJC_METTL3_EV_vs_WT_F07.14084.14084.2 2.75E-15 14/38 K.IGGDAGTSLNSNDYGYGGQK.R "sp|Q96AE4|FUBP1_HUMAN,tr|E9PEB5|E9PEB5_HUMAN,tr|C9JSZ1|C9JSZ1_HUMAN" 3 1972.8763 1.3 101188 14084 2 1972.874979 987.4454 Far upstream element-binding protein 1 OS=Homo sapiens OX=9606 GN=FUBP1 PE=1 SV=3 4.21 2507.6 - 311649 - - - -0.6508 - 3.392 0.758 - 607.4 1 2 0 -0.0013 20 0 0 0 2.96E+06 2.28E+06 - - - 7.6421 0.9996 221125_WJC_METTL3_EV_vs_WT_F07.14090.14090.3 7.98E-05 Nov-48 R.EK[136.11]NGVYISEENFR[166.11].V "sp|P52732|KIF11_HUMAN,tr|A0A7I2YQY4|A0A7I2YQY4_HUMAN,tr|A0A7I2V3A9|A0A7I2V3A9_HUMAN,tr|A0A7I2V3V3|A0A7I2V3V3_HUMAN" 4 1601.7805 6.76 101192 14090 3 1601.778012 534.9341 Kinesin-like protein KIF11 OS=Homo sapiens OX=9606 GN=KIF11 PE=1 SV=2 4.79 2508.3 - 1.40E+06 - - - -1.5258 - 2.116 0.462 - 166.5 1 2 1 -0.0024 13 0 0 0 7.64E+07 1.13E+07 - - - 5.7224 1 221125_WJC_METTL3_EV_vs_WT_F07.14095.14095.4 5.49E-05 17/96 K.K[136.11]LEVAMEEEGLADEEK[136.11]K[136.11].L "sp|Q9Y2H1|ST38L_HUMAN,tr|F5GY51|F5GY51_HUMAN,tr|I3L0D0|I3L0D0_HUMAN,tr|F5H7Z3|F5H7Z3_HUMAN" 4 1970.9933 4.69 101197 14095 4 1970.994278 493.7556 Serine\threonine-protein kinase 38-like OS=Homo sapiens OX=9606 GN=STK38L PE=1 SV=3 4.31 2508.9 - 552300 - - - 0.5094 - 3.479 0.506 - 279.9 1 2 0 0.001 17 0 0 0 2.41E+07 5.13E+06 - - - 4.0628 0.9707 221125_WJC_METTL3_EV_vs_WT_F07.14096.14096.4 0.13 Nov-78 K.LKEENFFNPKEEVK.L "sp|Q9Y6M1|IF2B2_HUMAN,tr|F8W930|F8W930_HUMAN" 2 1749.8938 1.53 101198 14096 4 1749.892954 438.4807 Insulin-like growth factor 2 mRNA-binding protein 2 OS=Homo sapiens OX=9606 GN=IGF2BP2 PE=1 SV=2 4.95 2509 - 586607 - - - -0.4555 - 1.768 0.211 - 56.5 1 2 2 -0.0008 14 0 0 0 8.41E+06 5.51E+06 - - - 1.2697 0.9998 221125_WJC_METTL3_EV_vs_WT_F07.14099.14099.2 8.33E-05 28-Jul R.NDSPTQIPVSSDVC[160.03]R[166.11].L sp|Q8TC07|TBC15_HUMAN 1 1683.7762 0.57 101201 14099 2 1683.775793 842.8954 TBC1 domain family member 15 OS=Homo sapiens OX=9606 GN=TBC1D15 PE=1 SV=2 4.21 2509.3 - 349568 - - - -0.2233 - 1.863 0.484 - 75.7 1 2 0 -0.0004 15 0 0 0 1.52E+06 2.68E+06 - - - 4.1454 0.9991 221125_WJC_METTL3_EV_vs_WT_F07.14108.14108.3 0.000118 15/68 K.LQIASDENYK[136.11]DPTNLQGK[136.11].L "sp|Q13813|SPTN1_HUMAN,tr|A0A0D9SFF6|A0A0D9SFF6_HUMAN,tr|A0A0D9SF54|A0A0D9SF54_HUMAN,tr|A0A0D9SGF6|A0A0D9SGF6_HUMAN" 4 2049.0349 1.72 101209 14108 3 2049.04214 684.0189 "Spectrin alpha chain, non-erythrocytic 1 OS=Homo sapiens OX=9606 GN=SPTAN1 PE=1 SV=3" 4.56 2510.4 - 468078 - - - 3.5095 - 2.869 0.465 - 235 1 2 1 0.0072 18 0 0 0 5.45E+07 3.17E+07 - - - 6.3468 0.8443 221125_WJC_METTL3_EV_vs_WT_F07.14113.14113.2 4.33E-05 26-Nov R.R[166.11]AEQDSTTVAAFAS.S "sp|Q86U44|MTA70_HUMAN,tr|F5H6D8|F5H6D8_HUMAN,tr|H0YFV6|H0YFV6_HUMAN,tr|B4DTN4|B4DTN4_HUMAN" 4 1462.6928 0.001 101212 14113 2 1462.685612 732.3537 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 4.37 2511.1 - 1.08E+06 - - - -4.8841 - 1.887 0.494 - 193.2 1 1 0 -0.0071 14 0 0 0 0.00E+00 1.66E+07 - - - 4.2809 1 221125_WJC_METTL3_EV_vs_WT_F07.14121.14121.2 3.02E-12 13/28 K.GVIVDK[136.11]DFSHPQMPK[136.11].K "sp|P48643|TCPE_HUMAN,tr|E9PCA1|E9PCA1_HUMAN,tr|B7ZAR1|B7ZAR1_HUMAN,tr|E7ENZ3|E7ENZ3_HUMAN" 4 1712.8891 0.38 101220 14121 2 1712.8921 857.4518 T-complex protein 1 subunit epsilon OS=Homo sapiens OX=9606 GN=CCT5 PE=1 SV=1 6.75 2512 - 222432 - - - 1.7649 - 2.739 0.656 - 499.8 1 2 1 0.003 15 0 0 0 2.59E+06 6.86E+06 - - - 6.3625 1 221125_WJC_METTL3_EV_vs_WT_F07.14122.14122.2 5.96E-10 13/32 K.RVEAAQETVADYQQTIK.K "sp|Q14203|DCTN1_HUMAN,tr|A0A804CDA6|A0A804CDA6_HUMAN,tr|E7EX90|E7EX90_HUMAN,tr|A0A7P0Z4C3|A0A7P0Z4C3_HUMAN,tr|Q6AWB1|Q6AWB1_HUMAN" 5 1948.9854 12.95 101221 14122 2 1948.985126 975.5 Dynactin subunit 1 OS=Homo sapiens OX=9606 GN=DCTN1 PE=1 SV=3 4.68 2512.2 - 206552 - - - -0.1508 - 2.83 0.574 - 263.4 1 2 0 -0.0003 17 0 0 0 3.00E+06 2.32E+05 - - - 5.838 0.9992 221125_WJC_METTL3_EV_vs_WT_F07.14125.14125.2 0.00101 30-Jul R.DSSDTTPLLNGSSQDR.M "tr|B4DQA8|B4DQA8_HUMAN,tr|E9PCW1|E9PCW1_HUMAN" 2 1691.7598 2.88 101223 14125 2 1691.755333 846.8872 28 kDa Golgi SNARE protein OS=Homo sapiens OX=9606 GN=GOSR1 PE=1 SV=1 3.93 2512.5 - 183045 - - - -2.6617 - 1.432 0.535 - 95.7 1 2 0 -0.0045 16 0 0 0 8.20E+06 2.85E+06 - - - 3.8739 1 221125_WJC_METTL3_EV_vs_WT_F07.14127.14127.3 4.14E-09 20/72 R.AIGSASEGAQSSLQEVYHK.S sp|P28066|PSA5_HUMAN 1 1960.949 0.81 101224 14127 3 1960.951356 654.657 Proteasome subunit alpha type-5 OS=Homo sapiens OX=9606 GN=PSMA5 PE=1 SV=3 5.4 2512.7 - 4.25E+06 - - - 1.1841 - 3.806 0.605 - 329.3 1 2 0 0.0023 19 0 0 0 1.58E+08 1.95E+08 - - - 8.5682 0.9991 221125_WJC_METTL3_EV_vs_WT_F07.14128.14128.3 0.000444 Dec-64 K.TVTLPENEDELESTNRR.Y "sp|P30876|RPB2_HUMAN,tr|C9J4M6|C9J4M6_HUMAN,tr|C9J2Y9|C9J2Y9_HUMAN" 3 2001.9603 1.11 101225 14128 3 2001.969868 668.3274 DNA-directed RNA polymerase II subunit RPB2 OS=Homo sapiens OX=9606 GN=POLR2B PE=1 SV=1 4.25 2512.8 - 1.54E+06 - - - 4.7658 - 2.03 0.476 - 144.8 1 2 0 0.0095 17 0 0 0 3.18E+07 2.85E+07 - - - 5.633 1 221125_WJC_METTL3_EV_vs_WT_F07.14129.14129.3 9.46E-06 Dec-72 R.AIGSASEGAQSSLQEVYHK[136.11].S sp|P28066|PSA5_HUMAN 1 1968.9632 0.79 101226 14129 3 1968.960136 657.3284 Proteasome subunit alpha type-5 OS=Homo sapiens OX=9606 GN=PSMA5 PE=1 SV=3 5.4 2512.8 - 5.16E+06 - - - -1.5734 - 2.6 0.528 - 97.1 1 2 0 -0.0031 19 0 0 0 1.59E+08 2.00E+08 - - - 6.7733 0.9999 221125_WJC_METTL3_EV_vs_WT_F07.14131.14131.3 1.89E-08 19/68 K.LQIASDENYKDPTNLQGK.L "sp|Q13813|SPTN1_HUMAN,tr|A0A0D9SFF6|A0A0D9SFF6_HUMAN,tr|A0A0D9SF54|A0A0D9SF54_HUMAN,tr|A0A0D9SGF6|A0A0D9SGF6_HUMAN" 4 2033.0065 1.81 101228 14131 3 2033.008781 678.6761 "Spectrin alpha chain, non-erythrocytic 1 OS=Homo sapiens OX=9606 GN=SPTAN1 PE=1 SV=3" 4.56 2513 - 1.30E+06 - - - 1.0979 - 3.605 0.598 - 340.8 1 2 1 0.0022 18 0 0 0 5.74E+07 3.17E+07 - - - 8.3996 1 221125_WJC_METTL3_EV_vs_WT_F07.14137.14137.4 9.31E-07 23/96 R.VVSHPTLPVTITAHEDR.H sp|Q13033|STRN3_HUMAN 1 1870.9901 1.22 101232 14137 4 1870.987143 468.7548 Striatin-3 OS=Homo sapiens OX=9606 GN=STRN3 PE=1 SV=3 5.99 2513.7 - 570198 - - - -1.5863 - 3.96 0.527 - 535.8 1 2 0 -0.003 17 0 0 0 1.34E+07 1.10E+07 - - - 4.29 0.9988 221125_WJC_METTL3_EV_vs_WT_F07.14138.14138.3 4.67E-05 Oct-64 K.TVTLPENEDELESTNR[166.11]R[166.11].Y "sp|P30876|RPB2_HUMAN,tr|C9J4M6|C9J4M6_HUMAN,tr|C9J2Y9|C9J2Y9_HUMAN" 3 2021.9769 1.13 101233 14138 3 2021.978596 674.9996 DNA-directed RNA polymerase II subunit RPB2 OS=Homo sapiens OX=9606 GN=POLR2B PE=1 SV=1 4.25 2513.8 - 1.33E+06 - - - 0.8551 - 1.934 0.27 - 105.8 1 2 0 0.0017 17 0 0 0 3.17E+07 2.80E+07 - - - 3.2161 0.9996 221125_WJC_METTL3_EV_vs_WT_F07.14140.14140.3 0.000204 14/64 K.QSAQLTALAAQQQAAGK.E sp|Q96A49|SYAP1_HUMAN 1 1683.8904 1.23 101235 14140 3 1683.897197 562.3041 Synapse-associated protein 1 OS=Homo sapiens OX=9606 GN=SYAP1 PE=1 SV=1 8.75 2514.1 - 430589 - - - 4.0383 - 2.863 0.417 - 255.6 1 2 0 0.0068 17 0 0 0 6.61E+06 5.37E+06 - - - 5.8446 1 221125_WJC_METTL3_EV_vs_WT_F07.14141.14141.2 1.29E-14 15/36 R.GVFAGTNTGPNNSNTTFQK.R "sp|Q9NYF8|BCLF1_HUMAN,tr|H0YF14|H0YF14_HUMAN" 2 1953.9181 2.99 101236 14141 2 1953.918931 977.9663 Bcl-2-associated transcription factor 1 OS=Homo sapiens OX=9606 GN=BCLAF1 PE=1 SV=2 8.75 2514.2 - 263111 - - - 0.4417 - 3.426 0.704 - 743.5 1 2 0 0.0009 19 0 0 0 1.61E+07 5.37E+06 - - - 7.2679 1 221125_WJC_METTL3_EV_vs_WT_F07.14142.14142.2 8.37E-07 13/32 K.QSAQLTALAAQQQAAGK.E sp|Q96A49|SYAP1_HUMAN 1 1683.8904 1.61 101237 14142 2 1683.896599 842.9525 Synapse-associated protein 1 OS=Homo sapiens OX=9606 GN=SYAP1 PE=1 SV=1 8.75 2514.3 - 235931 - - - 3.6831 - 2.983 0.633 - 555.1 1 2 0 0.0062 17 0 0 0 4.43E+06 2.75E+06 - - - 6.4014 0.8103 221125_WJC_METTL3_EV_vs_WT_F07.14143.14143.3 0.519 Sep-44 R.TGHSLLHTLYGR[166.11].S "sp|P31040|SDHA_HUMAN,tr|D6RFM5|D6RFM5_HUMAN,tr|A0A494C1T6|A0A494C1T6_HUMAN" 3 1363.7236 68.65 101238 14143 3 1363.719274 455.5818 "Succinate dehydrogenase [ubiquinone] flavoprotein subunit, mitochondrial OS=Homo sapiens OX=9606 GN=SDHA PE=1 SV=2" 8.47 2514.5 - 233323 - - - -3.1744 - 1.378 0.126 - 76.1 1 2 0 -0.0043 12 0 0 0 3.08E+08 4.48E+06 - - - 0.8323 1 221125_WJC_METTL3_EV_vs_WT_F07.14144.14144.2 8.82E-09 Dec-34 R.SSSVGSSSSYPISPAVSR[166.11].T "sp|Q15149|PLEC_HUMAN,tr|H0YDN1|H0YDN1_HUMAN" 2 1763.8565 2.04 101239 14144 2 1763.853708 882.9355 Plectin OS=Homo sapiens OX=9606 GN=PLEC PE=1 SV=3 8.46 2514.6 - 223232 - - - -1.5982 - 2.499 0.662 - 320.3 1 2 0 -0.0028 18 0 0 0 9.25E+06 4.53E+06 - - - 6.1814 1 221125_WJC_METTL3_EV_vs_WT_F07.14150.14150.4 6.58E-10 18/96 R.VVSHPTLPVTITAHEDR[166.11].H sp|Q13033|STRN3_HUMAN 1 1880.9984 1.22 101243 14150 4 1880.999749 471.2569 Striatin-3 OS=Homo sapiens OX=9606 GN=STRN3 PE=1 SV=3 5.99 2515.3 - 574429 - - - 0.7273 - 3.96 0.572 - 319.5 1 2 0 0.0014 17 0 0 0 1.34E+07 1.10E+07 - - - 4.6821 1 221125_WJC_METTL3_EV_vs_WT_F07.14151.14151.2 1.66E-09 13/34 R.SSSVGSSSSYPISPAVSR.T "sp|Q15149|PLEC_HUMAN,tr|H0YDN1|H0YDN1_HUMAN" 2 1753.8483 2.04 101244 14151 2 1753.850537 877.9314 Plectin OS=Homo sapiens OX=9606 GN=PLEC PE=1 SV=3 8.46 2515.4 - 357860 - - - 1.3 - 2.587 0.601 - 352.6 1 2 0 0.0023 18 0 0 0 9.25E+06 4.53E+06 - - - 5.8161 0.964 221125_WJC_METTL3_EV_vs_WT_F07.14159.14159.3 0.0197 Sep-36 R.KDAEAWFNEK.S "sp|P13645|K1C10_HUMAN,sp|Q7Z3Y7|K1C28_HUMAN,tr|A0A1B0GVI3|A0A1B0GVI3_HUMAN" 3 1236.5775 999 101250 14159 3 1236.579961 413.1998 "Keratin, type I cytoskeletal 10 OS=Homo sapiens OX=9606 GN=KRT10 PE=1 SV=6" 4.68 2516.4 - 139110 - - - 1.9886 - 1.716 0.117 - 96.4 1 2 0 0.0025 10 0 0 0 1.15E+07 0.00E+00 - - - 1.4208 1 221125_WJC_METTL3_EV_vs_WT_F07.14164.14164.3 3.55E-11 17/72 R.GVFAGTNTGPNNSNTTFQK.R "sp|Q9NYF8|BCLF1_HUMAN,tr|H0YF14|H0YF14_HUMAN" 2 1953.9181 3.49 101253 14164 3 1953.92101 652.3133 Bcl-2-associated transcription factor 1 OS=Homo sapiens OX=9606 GN=BCLAF1 PE=1 SV=2 8.75 2517 - 2.25E+06 - - - 1.5057 - 3.616 0.612 - 438.8 1 2 0 0.0029 19 0 0 0 3.45E+07 9.91E+06 - - - 8.5203 0.9229 221125_WJC_METTL3_EV_vs_WT_F07.14165.14165.3 1.99E-06 15/44 L.VDK[136.11]DFSHPQMPK[136.11].K "sp|P48643|TCPE_HUMAN,tr|E9PCA1|E9PCA1_HUMAN,tr|B7ZAR1|B7ZAR1_HUMAN,tr|E7ENZ3|E7ENZ3_HUMAN" 4 1443.7151 0.61 101254 14165 3 1443.720822 482.2457 T-complex protein 1 subunit epsilon OS=Homo sapiens OX=9606 GN=CCT5 PE=1 SV=1 6.72 2517.1 - 629065 - - - 3.9391 - 2.688 0.503 - 229.3 1 1 1 0.0057 12 0 0 0 1.01E+07 1.66E+07 - - - 6.8872 1 221125_WJC_METTL3_EV_vs_WT_F07.14167.14167.2 4.14E-09 18/38 K.NNPATPSTAMGSSVPYSTAK.T "sp|P35658|NU214_HUMAN,tr|A0A0A0MSW3|A0A0A0MSW3_HUMAN,tr|A0A494C1F2|A0A494C1F2_HUMAN,tr|A0A494C104|A0A494C104_HUMAN" 4 1979.9259 1.71 101256 14167 2 1979.929582 990.9702 Nuclear pore complex protein Nup214 OS=Homo sapiens OX=9606 GN=NUP214 PE=1 SV=2 8.59 2517.4 - 448776 - - - 1.8819 - 3.311 0.73 - 664.7 1 2 0 0.0037 20 0 0 0 1.70E+07 9.92E+06 - - - 7.3751 0.9882 221125_WJC_METTL3_EV_vs_WT_F07.14168.14168.2 6.18E-08 13/36 R.GVFAGTNTGPNNSNTTFQK[136.11].R "sp|Q9NYF8|BCLF1_HUMAN,tr|H0YF14|H0YF14_HUMAN" 2 1961.9323 2.99 101257 14168 2 1961.94214 981.9734 Bcl-2-associated transcription factor 1 OS=Homo sapiens OX=9606 GN=BCLAF1 PE=1 SV=2 8.75 2517.5 - 423748 - - - 5.0318 - 2.908 0.162 - 478.3 1 2 0 0.0099 19 0 0 0 1.61E+07 5.37E+06 - - - 2.8588 0.9999 221125_WJC_METTL3_EV_vs_WT_F07.14169.14169.3 2.53E-06 13/64 R.VVSHPTLPVTITAHEDR.H sp|Q13033|STRN3_HUMAN 1 1870.9901 1.53 101258 14169 3 1870.994594 624.6706 Striatin-3 OS=Homo sapiens OX=9606 GN=STRN3 PE=1 SV=3 5.99 2517.7 - 379308 - - - 2.3961 - 2.6 0.51 - 207.1 1 2 0 0.0045 17 0 0 0 3.65E+06 2.38E+06 - - - 6.6387 0.9999 221125_WJC_METTL3_EV_vs_WT_F07.14170.14170.3 4.13E-05 Dec-76 K.NNPATPSTAMGSSVPYSTAK[136.11].T "sp|P35658|NU214_HUMAN,tr|A0A0A0MSW3|A0A0A0MSW3_HUMAN,tr|A0A494C1F2|A0A494C1F2_HUMAN,tr|A0A494C104|A0A494C104_HUMAN" 4 1987.9401 0.51 101259 14170 3 1987.94249 663.654 Nuclear pore complex protein Nup214 OS=Homo sapiens OX=9606 GN=NUP214 PE=1 SV=2 8.59 2517.8 - 368640 - - - 1.2244 - 2.229 0.423 - 118.4 1 2 0 0.0024 20 0 0 0 1.30E+07 2.55E+07 - - - 5.1999 0.9982 221125_WJC_METTL3_EV_vs_WT_F07.14171.14171.2 0.0196 Sep-32 K.QSAQLTALAAQQQAAGK[136.11].E sp|Q96A49|SYAP1_HUMAN 1 1691.9046 1.61 101260 14171 2 1691.905791 846.9596 Synapse-associated protein 1 OS=Homo sapiens OX=9606 GN=SYAP1 PE=1 SV=1 8.75 2517.9 - 245574 - - - 0.7057 - 1.444 0.276 - 105.8 1 2 0 0.0012 17 0 0 0 4.43E+06 2.75E+06 - - - 1.9825 0.9867 221125_WJC_METTL3_EV_vs_WT_F07.14172.14172.2 0.0706 30-Jun K.SSSSSGVPYSPAIPNK[136.11].R "sp|Q9UPT5|EXOC7_HUMAN,tr|A0A0A0MSB8|A0A0A0MSB8_HUMAN,tr|B4DJ07|B4DJ07_HUMAN,tr|A0A0A0MRE1|A0A0A0MRE1_HUMAN" 4 1584.7875 0.84 101261 14172 2 1584.78922 793.401 Exocyst complex component 7 OS=Homo sapiens OX=9606 GN=EXOC7 PE=1 SV=3 8.31 2518.1 - 234666 - - - 1.0841 - 1.133 0.175 - 68.8 1 2 0 0.0017 16 0 0 0 2.17E+06 2.58E+06 - - - 0.64 1 221125_WJC_METTL3_EV_vs_WT_F07.14173.14173.2 2.92E-10 Dec-36 R.AIGSASEGAQSSLQEVYHK[136.11].S sp|P28066|PSA5_HUMAN 1 1968.9632 0.45 101262 14173 2 1968.968393 985.4889 Proteasome subunit alpha type-5 OS=Homo sapiens OX=9606 GN=PSMA5 PE=1 SV=3 5.4 2518.2 - 230196 - - - 2.6202 - 2.914 0.664 - 409.1 1 2 0 0.0052 19 0 0 0 1.36E+06 2.99E+06 - - - 6.5732 1 221125_WJC_METTL3_EV_vs_WT_F07.14174.14174.2 1.36E-12 17/38 K.NNPATPSTAMGSSVPYSTAK[136.11].T "sp|P35658|NU214_HUMAN,tr|A0A0A0MSW3|A0A0A0MSW3_HUMAN,tr|A0A494C1F2|A0A494C1F2_HUMAN,tr|A0A494C104|A0A494C104_HUMAN" 4 1987.9401 1.71 101263 14174 2 1987.94042 994.9773 Nuclear pore complex protein Nup214 OS=Homo sapiens OX=9606 GN=NUP214 PE=1 SV=2 8.59 2518.3 - 199500 - - - 0.1831 - 3.234 0.71 - 560.8 1 2 0 0.0004 20 0 0 0 1.70E+07 9.92E+06 - - - 7.1706 0.9999 221125_WJC_METTL3_EV_vs_WT_F07.14176.14176.4 1.05E-07 13/84 K.GVIVDK[136.11]DFSHPQMPK[136.11].K "sp|P48643|TCPE_HUMAN,tr|E9PCA1|E9PCA1_HUMAN,tr|B7ZAR1|B7ZAR1_HUMAN,tr|E7ENZ3|E7ENZ3_HUMAN" 4 1712.8891 0.59 101264 14176 4 1712.890628 429.2295 T-complex protein 1 subunit epsilon OS=Homo sapiens OX=9606 GN=CCT5 PE=1 SV=1 6.75 2518.5 - 2.17E+07 - - - 0.9055 - 2.727 0.528 - 94.1 1 2 1 0.0016 15 0 0 0 3.74E+08 6.37E+08 - - - 4.1802 1 221125_WJC_METTL3_EV_vs_WT_F07.14178.14178.3 2.41E-09 16/52 K.DHASIQMNVAEVDK[136.11].V "sp|P63220|RS21_HUMAN,tr|Q9BYK1|Q9BYK1_HUMAN,tr|Q8WVC2|Q8WVC2_HUMAN" 3 1563.7443 0.36 101265 14178 3 1563.746147 522.2554 40S ribosomal protein S21 OS=Homo sapiens OX=9606 GN=RPS21 PE=1 SV=1 4.54 2518.8 - 3.11E+06 - - - 1.2093 - 3.402 0.64 - 606 1 2 0 0.0019 14 0 0 0 1.88E+07 5.27E+07 - - - 8.9286 0.9998 221125_WJC_METTL3_EV_vs_WT_F07.14179.14179.3 0.000154 13/52 R.DKFQETSDEFEAAR.K "sp|Q14683|SMC1A_HUMAN,tr|G8JLG1|G8JLG1_HUMAN,tr|A0A6Q8PHC3|A0A6Q8PHC3_HUMAN,tr|V9GY57|V9GY57_HUMAN" 4 1671.7376 1.06 101266 14179 3 1671.740173 558.2532 Structural maintenance of chromosomes protein 1A OS=Homo sapiens OX=9606 GN=SMC1A PE=1 SV=2 4.18 2518.8 - 1.83E+06 - - - 1.5128 - 2.18 0.522 - 252.8 1 2 1 0.0025 14 0 0 0 4.48E+07 4.24E+07 - - - 6.4302 0.8741 221125_WJC_METTL3_EV_vs_WT_F07.14181.14181.2 0.0433 12-Jun T.VGEQLLK.S "sp|Q4ADV7|RIC1_HUMAN,tr|H0YFN7|H0YFN7_HUMAN" 2 785.4647 999 101268 14181 2 785.465217 393.7396 Guanine nucleotide exchange factor subunit RIC1 OS=Homo sapiens OX=9606 GN=RIC1 PE=1 SV=2 5.97 2519.1 - 679951 - - - 0.6531 - 1.304 0.254 - 107.9 1 1 0 0.0005 7 0 0 0 7.55E+06 0.00E+00 - - - 1.7579 1 221125_WJC_METTL3_EV_vs_WT_F07.14184.14184.4 1.14E-05 15/72 R.DWQSYYYHHPQDR.D sp|Q1KMD3|HNRL2_HUMAN 1 1793.7546 1.28 101271 14184 4 1793.756126 449.4459 Heterogeneous nuclear ribonucleoprotein U-like protein 2 OS=Homo sapiens OX=9606 GN=HNRNPUL2 PE=1 SV=1 5.98 2519.5 - 470037 - - - 0.8329 - 2.614 0.518 - 191.7 1 2 0 0.0015 13 0 0 0 9.83E+06 7.66E+06 - - - 4.0905 0.9999 221125_WJC_METTL3_EV_vs_WT_F07.14185.14185.4 0.000504 13/72 R.DWQSYYYHHPQDR[166.11].D sp|Q1KMD3|HNRL2_HUMAN 1 1803.7629 1.31 101272 14185 4 1803.763092 451.948 Heterogeneous nuclear ribonucleoprotein U-like protein 2 OS=Homo sapiens OX=9606 GN=HNRNPUL2 PE=1 SV=1 5.98 2519.6 - 464978 - - - 0.1053 - 2.369 0.469 - 136.3 1 2 0 0.0002 13 0 0 0 9.90E+06 7.58E+06 - - - 3.6279 1 221125_WJC_METTL3_EV_vs_WT_F07.14186.14186.2 3.62E-05 18/26 K.DHASIQMNVAEVDK[136.11].V "sp|P63220|RS21_HUMAN,tr|Q9BYK1|Q9BYK1_HUMAN,tr|Q8WVC2|Q8WVC2_HUMAN" 3 1563.7443 0.34 101273 14186 2 1563.74695 782.8794 40S ribosomal protein S21 OS=Homo sapiens OX=9606 GN=RPS21 PE=1 SV=1 4.54 2519.7 - 383044 - - - 1.7228 - 3.778 0.712 - 941.4 1 2 0 0.0027 14 0 0 0 1.58E+06 4.69E+06 - - - 7.6345 1 221125_WJC_METTL3_EV_vs_WT_F07.14187.14187.3 3.96E-06 Dec-60 R.LAQMISDHNDADFEEK.V "sp|Q14157|UBP2L_HUMAN,tr|Q5VU78|Q5VU78_HUMAN,tr|F8W726|F8W726_HUMAN,tr|Q5VU81|Q5VU81_HUMAN,tr|Q5VU79|Q5VU79_HUMAN,tr|Q5VU80|Q5VU80_HUMAN,tr|Q5VU77|Q5VU77_HUMAN" 7 1861.8152 2.69 101274 14187 3 1861.819297 621.6124 Ubiquitin-associated protein 2-like OS=Homo sapiens OX=9606 GN=UBAP2L PE=1 SV=2 4.1 2519.9 - 282141 - - - 2.1774 - 2.627 0.533 - 190.9 1 2 0 0.0041 16 0 0 0 1.36E+07 5.04E+06 - - - 6.9595 0.9349 221125_WJC_METTL3_EV_vs_WT_F07.14188.14188.3 0.00279 Sep-76 Q.VQSTTVTSHLNSTSVDPYDR[166.11].H sp|Q9BQ04|RBM4B_HUMAN 1 2216.0585 2.47 101275 14188 3 2216.057598 739.6934 RNA-binding protein 4B OS=Homo sapiens OX=9606 GN=RBM4B PE=1 SV=1 5.21 2520 - 248582 - - - -0.3957 - 1.657 0.345 - 52.3 1 1 0 -0.0009 20 0 0 0 4.62E+06 1.87E+06 - - - 3.6113 1 221125_WJC_METTL3_EV_vs_WT_F07.14193.14193.3 5.72E-08 16/48 R.HLDTLTEHYDIPK.V "sp|Q9Y421|FA32A_HUMAN,tr|K7EIY1|K7EIY1_HUMAN" 2 1580.7835 0.85 101278 14193 3 1580.782792 527.9351 Protein FAM32A OS=Homo sapiens OX=9606 GN=FAM32A PE=1 SV=2 5.21 2520.7 - 2.02E+06 - - - -0.4302 - 2.677 0.563 - 295.4 1 2 0 -0.0007 13 0 0 0 2.64E+07 3.10E+07 - - - 7.4865 0.9998 221125_WJC_METTL3_EV_vs_WT_F07.14195.14195.3 1.68E-05 Nov-48 K.SVEEGK[136.11]IDGIIDK[136.11].T sp|Q96A49|SYAP1_HUMAN 1 1417.7635 1.59 101280 14195 3 1417.764693 473.5951 Synapse-associated protein 1 OS=Homo sapiens OX=9606 GN=SYAP1 PE=1 SV=1 4.32 2520.8 - 1.97E+06 - - - 0.8238 - 2.131 0.483 - 98.7 1 2 1 0.0012 13 0 0 0 3.88E+07 2.44E+07 - - - 5.976 1 221125_WJC_METTL3_EV_vs_WT_F07.14198.14198.3 3.91E-11 17/76 K.NNPATPSTAMGSSVPYSTAK.T "sp|P35658|NU214_HUMAN,tr|A0A0A0MSW3|A0A0A0MSW3_HUMAN,tr|A0A494C1F2|A0A494C1F2_HUMAN,tr|A0A494C104|A0A494C104_HUMAN" 4 1979.9259 0.52 101282 14198 3 1979.931849 660.9826 Nuclear pore complex protein Nup214 OS=Homo sapiens OX=9606 GN=NUP214 PE=1 SV=2 8.59 2521.1 - 1.00E+06 - - - 3.0269 - 2.971 0.622 - 256 1 2 0 0.006 20 0 0 0 1.23E+07 2.38E+07 - - - 8.1147 1 221125_WJC_METTL3_EV_vs_WT_F07.14199.14199.3 5.98E-05 21/76 K.TNVNGGAIALGHPLGGSGSR[166.11].L "sp|P42765|THIM_HUMAN,tr|K7EME0|K7EME0_HUMAN,tr|A0A0B4J2A4|A0A0B4J2A4_HUMAN" 3 1843.9528 1.41 101283 14199 3 1843.956026 615.6582 "3-ketoacyl-CoA thiolase, mitochondrial OS=Homo sapiens OX=9606 GN=ACAA2 PE=1 SV=2" 9.44 2521.2 - 784088 - - - 1.7343 - 3.683 0.527 - 411 1 2 0 0.0032 20 0 0 0 1.50E+07 1.06E+07 - - - 7.5775 1 221125_WJC_METTL3_EV_vs_WT_F07.14200.14200.3 2.17E-07 16/48 R.DWQSYYYHHPQDR.D sp|Q1KMD3|HNRL2_HUMAN 1 1793.7546 1.47 101284 14200 3 1793.754312 598.9255 Heterogeneous nuclear ribonucleoprotein U-like protein 2 OS=Homo sapiens OX=9606 GN=HNRNPUL2 PE=1 SV=1 5.98 2521.3 - 682371 - - - -0.1784 - 2.615 0.588 - 427.9 1 2 0 -0.0003 13 0 0 0 5.80E+06 3.95E+06 - - - 7.7018 1 221125_WJC_METTL3_EV_vs_WT_F07.14201.14201.2 6.71E-09 15/26 R.DKFQETSDEFEAAR.K "sp|Q14683|SMC1A_HUMAN,tr|G8JLG1|G8JLG1_HUMAN,tr|A0A6Q8PHC3|A0A6Q8PHC3_HUMAN,tr|V9GY57|V9GY57_HUMAN" 4 1671.7376 0.61 101285 14201 2 1671.736349 836.8761 Structural maintenance of chromosomes protein 1A OS=Homo sapiens OX=9606 GN=SMC1A PE=1 SV=2 4.18 2521.4 - 501665 - - - -0.7746 - 3.117 0.603 - 1057.9 1 2 1 -0.0013 14 0 0 0 5.23E+06 8.55E+06 - - - 6.3473 0.9997 221125_WJC_METTL3_EV_vs_WT_F07.14202.14202.2 8.60E-07 28-Dec R.SNTPSPLNLSSTSSK.N "sp|O60315|ZEB2_HUMAN,tr|U3KQ51|U3KQ51_HUMAN,tr|A0JP08|A0JP08_HUMAN,tr|A0A1B0GW50|A0A1B0GW50_HUMAN,tr|A0A1B0GV02|A0A1B0GV02_HUMAN,tr|A0A1B0GVV8|A0A1B0GVV8_HUMAN" 6 1518.7526 2.15 101286 14202 2 1518.755471 760.3836 Zinc finger E-box-binding homeobox 2 OS=Homo sapiens OX=9606 GN=ZEB2 PE=1 SV=1 8.47 2521.6 - 441910 - - - 1.9128 - 2.189 0.51 - 423.9 1 2 0 0.0029 15 0 0 0 8.37E+06 3.89E+06 - - - 4.7331 1 221125_WJC_METTL3_EV_vs_WT_F07.14205.14205.2 6.85E-06 13/26 K.DHASIQMNVAEVDK.V "sp|P63220|RS21_HUMAN,tr|Q9BYK1|Q9BYK1_HUMAN,tr|Q8WVC2|Q8WVC2_HUMAN" 3 1555.7301 0.34 101289 14205 2 1555.733613 778.8723 40S ribosomal protein S21 OS=Homo sapiens OX=9606 GN=RPS21 PE=1 SV=1 4.54 2522 - 238800 - - - 2.2864 - 2.795 0.619 - 417.2 1 2 0 0.0036 14 0 0 0 1.58E+06 4.69E+06 - - - 6.1911 0.9991 221125_WJC_METTL3_EV_vs_WT_F07.14208.14208.3 0.000513 Oct-48 K.SVEEGKIDGIIDK.T sp|Q96A49|SYAP1_HUMAN 1 1401.7351 1.62 101290 14208 3 1401.735592 468.2523 Synapse-associated protein 1 OS=Homo sapiens OX=9606 GN=SYAP1 PE=1 SV=1 4.32 2522.4 - 3.69E+06 - - - 0.3332 - 1.952 0.383 - 71.6 1 2 1 0.0005 13 0 0 0 4.04E+07 2.49E+07 - - - 4.6234 0.9891 221125_WJC_METTL3_EV_vs_WT_F07.14209.14209.4 1.99E-05 10/102 G.LLQDDAHPTLVTYADHSK[136.11].L "sp|Q86U44|MTA70_HUMAN,tr|F5H6D8|F5H6D8_HUMAN,tr|H0YFV6|H0YFV6_HUMAN,tr|B4DTN4|B4DTN4_HUMAN" 4 2031.0153 0.12 101291 14209 4 2031.016293 508.7611 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 5.13 2522.4 - 2.65E+06 - - - 0.5037 - 2.036 0.434 - 67.5 1 1 0 0.001 18 0 0 0 1.96E+06 1.61E+07 - - - 3.2468 1 221125_WJC_METTL3_EV_vs_WT_F07.14210.14210.3 1.30E-09 16/52 K.DHASIQMNVAEVDK.V "sp|P63220|RS21_HUMAN,tr|Q9BYK1|Q9BYK1_HUMAN,tr|Q8WVC2|Q8WVC2_HUMAN" 3 1555.7301 0.36 101292 14210 3 1555.73291 519.584 40S ribosomal protein S21 OS=Homo sapiens OX=9606 GN=RPS21 PE=1 SV=1 4.54 2522.5 - 2.12E+06 - - - 1.8345 - 3.318 0.619 - 575 1 2 0 0.0029 14 0 0 0 1.88E+07 5.19E+07 - - - 8.6278 0.9998 221125_WJC_METTL3_EV_vs_WT_F07.14212.14212.3 4.49E-10 17/48 R.HLDTLTEHYDIPK[136.11].V "sp|Q9Y421|FA32A_HUMAN,tr|K7EIY1|K7EIY1_HUMAN" 2 1588.7977 0.83 101294 14212 3 1588.795777 530.6065 Protein FAM32A OS=Homo sapiens OX=9606 GN=FAM32A PE=1 SV=2 5.21 2522.6 - 1.43E+06 - - - -1.1927 - 2.907 0.274 - 286.7 1 2 0 -0.0019 13 0 0 0 2.69E+07 3.25E+07 - - - 4.4876 1 221125_WJC_METTL3_EV_vs_WT_F07.14213.14213.3 1.71E-06 15/76 K.TNVNGGAIALGHPLGGSGSR.L "sp|P42765|THIM_HUMAN,tr|K7EME0|K7EME0_HUMAN,tr|A0A0B4J2A4|A0A0B4J2A4_HUMAN" 3 1833.9446 1.36 101295 14213 3 1833.946273 612.3221 "3-ketoacyl-CoA thiolase, mitochondrial OS=Homo sapiens OX=9606 GN=ACAA2 PE=1 SV=2" 9.44 2522.6 - 1.18E+06 - - - 0.9351 - 2.303 0.496 - 202.2 1 2 0 0.0017 20 0 0 0 1.44E+07 1.06E+07 - - - 6.0933 0.9999 221125_WJC_METTL3_EV_vs_WT_F07.14216.14216.3 5.67E-06 Nov-48 R.DWQSYYYHHPQDR[166.11].D sp|Q1KMD3|HNRL2_HUMAN 1 1803.7629 1.47 101298 14216 3 1803.767119 602.2616 Heterogeneous nuclear ribonucleoprotein U-like protein 2 OS=Homo sapiens OX=9606 GN=HNRNPUL2 PE=1 SV=1 5.98 2523 - 497262 - - - 2.3379 - 2.186 0.528 - 178.9 1 2 0 0.0042 13 0 0 0 5.80E+06 3.95E+06 - - - 6.5459 0.9999 221125_WJC_METTL3_EV_vs_WT_F07.14218.14218.3 3.17E-06 17/84 R.ILQGPHANPVAVPQPGASVQTK[136.11].G "sp|Q6NSI4|RADX_HUMAN,tr|B1AQ74|B1AQ74_HUMAN" 2 2216.2157 0.8 101300 14218 3 2216.213547 739.7458 RPA-related protein RADX OS=Homo sapiens OX=9606 GN=RADX PE=1 SV=2 8.76 2523.3 - 387539 - - - -0.9719 - 2.402 0.431 - 196.5 1 2 0 -0.0022 22 0 0 0 6.83E+06 8.50E+06 - - - 5.4222 0.9999 221125_WJC_METTL3_EV_vs_WT_F07.14219.14219.3 0.00156 15/84 R.ILQGPHANPVAVPQPGASVQTK.G "sp|Q6NSI4|RADX_HUMAN,tr|B1AQ74|B1AQ74_HUMAN" 2 2208.2015 0.79 101301 14219 3 2208.207757 737.0744 RPA-related protein RADX OS=Homo sapiens OX=9606 GN=RADX PE=1 SV=2 8.76 2523.4 - 371296 - - - 2.8331 - 2.751 0.464 - 146.7 1 2 0 0.0063 22 0 0 0 6.73E+06 8.50E+06 - - - 6.1106 0.9997 221125_WJC_METTL3_EV_vs_WT_F07.14226.14226.3 1.63E-06 14/52 R.DK[136.11]FQETSDEFEAAR[166.11].K "sp|Q14683|SMC1A_HUMAN,tr|G8JLG1|G8JLG1_HUMAN,tr|A0A6Q8PHC3|A0A6Q8PHC3_HUMAN,tr|V9GY57|V9GY57_HUMAN" 4 1689.7601 1.05 101306 14226 3 1689.763301 564.2606 Structural maintenance of chromosomes protein 1A OS=Homo sapiens OX=9606 GN=SMC1A PE=1 SV=2 4.18 2524.3 - 3.48E+06 - - - 1.8861 - 2.782 0.444 - 262.4 1 2 1 0.0032 14 0 0 0 4.47E+07 4.24E+07 - - - 6.2084 1 221125_WJC_METTL3_EV_vs_WT_F07.14227.14227.3 5.99E-05 14/52 R.NALQQENHIIDGVK.V "sp|Q9GZT3|SLIRP_HUMAN,tr|H0YJW7|H0YJW7_HUMAN,tr|A0A087WUN7|A0A087WUN7_HUMAN,tr|G3V2S9|G3V2S9_HUMAN,tr|H0YJ40|H0YJ40_HUMAN,tr|G3V4X6|G3V4X6_HUMAN" 6 1577.8162 2.54 101307 14227 3 1577.816579 526.946 "SRA stem-loop-interacting RNA-binding protein, mitochondrial OS=Homo sapiens OX=9606 GN=SLIRP PE=1 SV=1" 5.32 2524.4 - 3.10E+06 - - - 0.2599 - 2.482 0.445 - 268.1 1 2 0 0.0004 14 0 0 0 3.59E+07 1.41E+07 - - - 5.9171 0.9837 221125_WJC_METTL3_EV_vs_WT_F07.14229.14229.3 0.0181 Oct-52 R.NALQQENHIIDGVK[136.11].V "sp|Q9GZT3|SLIRP_HUMAN,tr|H0YJW7|H0YJW7_HUMAN,tr|A0A087WUN7|A0A087WUN7_HUMAN,tr|G3V2S9|G3V2S9_HUMAN,tr|H0YJ40|H0YJ40_HUMAN,tr|G3V4X6|G3V4X6_HUMAN" 6 1585.8304 2.54 101309 14229 3 1585.836811 529.6174 "SRA stem-loop-interacting RNA-binding protein, mitochondrial OS=Homo sapiens OX=9606 GN=SLIRP PE=1 SV=1" 5.32 2524.5 - 1.77E+06 - - - 4.0622 - 1.798 0.246 - 135.8 1 2 0 0.0064 14 0 0 0 3.58E+07 1.41E+07 - - - 2.84 0.9998 221125_WJC_METTL3_EV_vs_WT_F07.14234.14234.4 3.31E-06 18/84 K.LRNEYGPVLHMPTSK.E "sp|O43660|PLRG1_HUMAN,tr|D6RA26|D6RA26_HUMAN,tr|B7Z982|B7Z982_HUMAN" 3 1740.8981 9.69 101314 14234 4 1740.899859 436.2318 Pleiotropic regulator 1 OS=Homo sapiens OX=9606 GN=PLRG1 PE=1 SV=1 8.6 2525.1 - 694579 - - - 0.996 - 3.036 0.459 - 216.7 1 2 1 0.0017 15 0 0 0 2.46E+07 2.54E+06 - - - 3.618 0.9999 221125_WJC_METTL3_EV_vs_WT_F07.14235.14235.3 5.47E-10 20/52 R.QRPSEIKDYSPYFK.T sp|P08779|K1C16_HUMAN 1 1756.8784 189.19 101315 14235 3 1756.877245 586.6334 "Keratin, type I cytoskeletal 16 OS=Homo sapiens OX=9606 GN=KRT16 PE=1 SV=4" 8.43 2525.2 - 684033 - - - -0.6773 - 3.459 0.532 - 459.9 1 2 1 -0.0012 14 0 0 0 3.44E+08 1.82E+06 - - - 7.7689 1 221125_WJC_METTL3_EV_vs_WT_F07.14236.14236.4 7.94E-05 22/78 K.NQDHYAVLGLGHVR[166.11].Y "sp|Q99543|DNJC2_HUMAN,tr|F2Z3H0|F2Z3H0_HUMAN,tr|C9IZ83|C9IZ83_HUMAN,tr|H7C3L7|H7C3L7_HUMAN,tr|F2Z3N9|F2Z3N9_HUMAN" 5 1587.8145 0.83 101316 14236 4 1587.816704 397.9609 DnaJ homolog subfamily C member 2 OS=Homo sapiens OX=9606 GN=DNAJC2 PE=1 SV=4 6.92 2525.4 - 634004 - - - 1.361 - 3.072 0.495 - 565.1 1 2 0 0.0022 14 0 0 0 1.36E+07 1.65E+07 - - - 3.9423 0.9997 221125_WJC_METTL3_EV_vs_WT_F07.14237.14237.3 0.0052 Dec-60 R.KLTALDYHNPAGFNC[160.03]K.D "sp|Q9Y224|RTRAF_HUMAN,tr|G3V4C6|G3V4C6_HUMAN,tr|G3V4E7|G3V4E7_HUMAN" 3 1847.8989 1.15 101317 14237 3 1847.901897 616.9736 "RNA transcription, translation and transport factor protein OS=Homo sapiens OX=9606 GN=RTRAF PE=1 SV=1" 8.18 2525.5 - 600956 - - - 1.6473 - 2.112 0.363 - 132.6 1 2 0 0.003 16 0 0 0 4.73E+06 4.11E+06 - - - 4.5046 0.9999 221125_WJC_METTL3_EV_vs_WT_F07.14239.14239.4 6.68E-05 18/78 K.NQDHYAVLGLGHVR.Y "sp|Q99543|DNJC2_HUMAN,tr|F2Z3H0|F2Z3H0_HUMAN,tr|C9IZ83|C9IZ83_HUMAN,tr|H7C3L7|H7C3L7_HUMAN,tr|F2Z3N9|F2Z3N9_HUMAN" 5 1577.8063 0.83 101319 14239 4 1577.80805 395.4588 DnaJ homolog subfamily C member 2 OS=Homo sapiens OX=9606 GN=DNAJC2 PE=1 SV=4 6.92 2525.7 - 455862 - - - 1.1262 - 3.046 0.453 - 324.6 1 2 0 0.0018 14 0 0 0 1.35E+07 1.63E+07 - - - 3.5738 0.9997 221125_WJC_METTL3_EV_vs_WT_F07.14241.14241.3 0.000221 19/56 K.LRNEYGPVLHMPTSK.E "sp|O43660|PLRG1_HUMAN,tr|D6RA26|D6RA26_HUMAN,tr|B7Z982|B7Z982_HUMAN" 3 1740.8981 11.56 101321 14241 3 1740.90338 581.3067 Pleiotropic regulator 1 OS=Homo sapiens OX=9606 GN=PLRG1 PE=1 SV=1 8.6 2526 - 386424 - - - 3.0186 - 3.455 0.488 - 470.6 1 2 1 0.0053 15 0 0 0 1.44E+07 1.25E+06 - - - 7.2144 0.9801 221125_WJC_METTL3_EV_vs_WT_F07.14243.14243.3 0.264 Oct-64 R.KPEDVLDDDDAGSAPLK.S "sp|P35613|BASI_HUMAN,tr|A0A087WUV8|A0A087WUV8_HUMAN,tr|A0A7P0TA85|A0A7P0TA85_HUMAN" 3 1783.8476 4.86 101323 14243 3 1783.848878 595.6231 Basigin OS=Homo sapiens OX=9606 GN=BSG PE=1 SV=2 3.9 2526.3 - 310338 - - - 0.7226 - 1.753 0.129 - 86.9 1 2 0 0.0013 17 0 0 0 4.78E+06 9.83E+05 - - - 1.396 0.9998 221125_WJC_METTL3_EV_vs_WT_F07.14245.14245.4 1.01E-05 Dec-84 K.GVIVDKDFSHPQMPK.K "sp|P48643|TCPE_HUMAN,tr|E9PCA1|E9PCA1_HUMAN,tr|B7ZAR1|B7ZAR1_HUMAN,tr|E7ENZ3|E7ENZ3_HUMAN" 4 1696.8607 0.59 101324 14245 4 1696.863887 425.2224 T-complex protein 1 subunit epsilon OS=Homo sapiens OX=9606 GN=CCT5 PE=1 SV=1 6.75 2526.5 - 2.03E+06 - - - 1.8917 - 2.474 0.521 - 60.1 1 2 1 0.0032 15 0 0 0 3.73E+08 6.36E+08 - - - 4.084 0.9991 221125_WJC_METTL3_EV_vs_WT_F07.14247.14247.4 0.00546 Dec-78 R.QRPSEIKDYSPYFK.T sp|P08779|K1C16_HUMAN 1 1756.8784 3857.37 101326 14247 4 1756.880918 440.2269 "Keratin, type I cytoskeletal 16 OS=Homo sapiens OX=9606 GN=KRT16 PE=1 SV=4" 8.43 2526.7 - 6.61E+06 - - - 1.4133 - 2.384 0.376 - 135.3 1 2 1 0.0025 14 0 0 0 4.67E+08 1.21E+05 - - - 2.8142 0.9995 221125_WJC_METTL3_EV_vs_WT_F07.14249.14249.3 0.00489 16/64 K.MAPVPLDDSNRPASLTK.D "sp|Q9NYF8|BCLF1_HUMAN,tr|E9PKI6|E9PKI6_HUMAN,tr|A0A1W2PQ43|A0A1W2PQ43_HUMAN,tr|E9PK91|E9PK91_HUMAN,tr|E9PJA7|E9PJA7_HUMAN,tr|E9PK09|E9PK09_HUMAN,tr|E9PQN2|E9PQN2_HUMAN" 7 1810.9247 2.52 101328 14249 3 1810.927793 604.6489 Bcl-2-associated transcription factor 1 OS=Homo sapiens OX=9606 GN=BCLAF1 PE=1 SV=2 5.71 2526.8 - 798065 - - - 1.6892 - 2.368 0.305 - 204.1 1 2 0 0.0031 17 0 0 0 9.91E+07 3.94E+07 - - - 4.1174 1 221125_WJC_METTL3_EV_vs_WT_F07.14250.14250.3 4.86E-11 23/72 K.THSVNGITEEADPTIYSGK.V "sp|O75534|CSDE1_HUMAN,tr|E9PLT0|E9PLT0_HUMAN" 2 2017.9593 0.56 101329 14250 3 2017.963067 673.6604 Cold shock domain-containing protein E1 OS=Homo sapiens OX=9606 GN=CSDE1 PE=1 SV=2 4.65 2526.9 - 608821 - - - 1.8841 - 4.257 0.613 - 783 1 2 0 0.0038 19 0 0 0 3.10E+07 5.51E+07 - - - 8.9321 0.9999 221125_WJC_METTL3_EV_vs_WT_F07.14252.14252.3 0.000154 19/80 K.AEPAAPPAAPSTPAPPPAVPK[136.11].E sp|P48634|PRC2A_HUMAN 1 1941.0451 1.65 101331 14252 3 1941.044134 648.0223 Protein PRRC2A OS=Homo sapiens OX=9606 GN=PRRC2A PE=1 SV=3 6.05 2527.2 - 319290 - - - -0.5044 - 2.605 0.436 - 292.1 1 2 0 -0.001 21 0 0 0 1.48E+07 8.95E+06 - - - 5.6961 1 221125_WJC_METTL3_EV_vs_WT_F07.14257.14257.3 3.64E-07 20/56 M.PGHLQEGFGC[160.03]VVTNR[166.11].F sp|Q8NC51|PAIRB_HUMAN 1 1679.8077 0.79 101334 14257 3 1679.808678 560.9432 Plasminogen activator inhibitor 1 RNA-binding protein OS=Homo sapiens OX=9606 GN=SERBP1 PE=1 SV=2 7.13 2527.8 - 1.01E+06 - - - 0.556 - 3.422 0.554 - 572.8 1 2 0 0.0009 15 0 0 0 6.59E+06 8.36E+06 - - - 7.9264 0.9985 221125_WJC_METTL3_EV_vs_WT_F07.14258.14258.3 7.81E-09 21/76 R.TQSSASLAASYAAQQHPQAA.A sp|Q96PK6|RBM14_HUMAN 1 1986.9395 - 101335 14258 3 1986.942069 663.3205 RNA-binding protein 14 OS=Homo sapiens OX=9606 GN=RBM14 PE=1 SV=2 6.4 2527.9 - 1.46E+06 - - - 1.2768 - 3.861 0.562 - 678.5 1 1 0 0.0025 20 0 0 0 - - - - - 8.0824 1 221125_WJC_METTL3_EV_vs_WT_F07.14260.14260.3 1.13E-05 15/44 R.K[136.11]QMVIDVLHPGK[136.11].A "sp|P62847|RS24_HUMAN,tr|A0A2R8YD14|A0A2R8YD14_HUMAN,tr|A0A2R8Y849|A0A2R8Y849_HUMAN,tr|E7ETK0|E7ETK0_HUMAN" 4 1379.793 0.89 101337 14260 3 1379.794817 460.9383 40S ribosomal protein S24 OS=Homo sapiens OX=9606 GN=RPS24 PE=1 SV=1 8.6 2528.1 - 1.44E+06 - - - 1.3234 - 3.28 0.53 - 353.4 1 2 0 0.0018 12 0 0 0 1.88E+07 2.12E+07 - - - 7.741 1 221125_WJC_METTL3_EV_vs_WT_F07.14261.14261.3 2.99E-08 17/44 R.KQMVIDVLHPGK.A "sp|P62847|RS24_HUMAN,tr|A0A2R8YD14|A0A2R8YD14_HUMAN,tr|A0A2R8Y849|A0A2R8Y849_HUMAN,tr|E7ETK0|E7ETK0_HUMAN" 4 1363.7646 0.88 101338 14261 3 1363.766625 455.5955 40S ribosomal protein S24 OS=Homo sapiens OX=9606 GN=RPS24 PE=1 SV=1 8.6 2528.1 - 1.19E+06 - - - 1.4915 - 3.122 0.589 - 490.5 1 2 0 0.002 12 0 0 0 1.88E+07 2.14E+07 - - - 8.2619 1 221125_WJC_METTL3_EV_vs_WT_F07.14262.14262.2 1.11E-11 18/32 K.LNQVC[160.03]FDDDGTSSPQDR.L "sp|Q8N1F7|NUP93_HUMAN,tr|H3BPA9|H3BPA9_HUMAN,tr|H3BVG0|H3BVG0_HUMAN" 3 1952.817 2.49 101339 14262 2 1952.818721 977.4158 Nuclear pore complex protein Nup93 OS=Homo sapiens OX=9606 GN=NUP93 PE=1 SV=2 3.77 2528.3 - 1.16E+06 - - - 0.8639 - 3.424 0.765 - 1269 1 2 0 0.0017 17 0 0 0 1.57E+07 6.31E+06 - - - 7.7168 0.9998 221125_WJC_METTL3_EV_vs_WT_F07.14263.14263.4 0.000253 16/84 K.ILQINK[136.11]DDVTALHC[160.03]K[136.11].V "sp|O76094|SRP72_HUMAN,tr|R4GNC1|R4GNC1_HUMAN,tr|D6RDY6|D6RDY6_HUMAN" 3 1782.9633 0.47 101340 14263 4 1782.962678 446.7481 Signal recognition particle subunit SRP72 OS=Homo sapiens OX=9606 GN=SRP72 PE=1 SV=3 6.74 2528.4 - 844319 - - - -0.3517 - 2.749 0.467 - 251 1 2 1 -0.0006 15 0 0 0 6.10E+06 1.29E+07 - - - 3.6524 1 221125_WJC_METTL3_EV_vs_WT_F07.14264.14264.3 1.75E-07 18/64 K.LNQVC[160.03]FDDDGTSSPQDR.L "sp|Q8N1F7|NUP93_HUMAN,tr|H3BPA9|H3BPA9_HUMAN,tr|H3BVG0|H3BVG0_HUMAN" 3 1952.817 2.29 101341 14264 3 1952.822018 651.9463 Nuclear pore complex protein Nup93 OS=Homo sapiens OX=9606 GN=NUP93 PE=1 SV=2 3.77 2528.5 - 832058 - - - 2.5522 - 3.079 0.672 - 485.4 1 2 0 0.005 17 0 0 0 9.66E+06 4.21E+06 - - - 8.8718 1 221125_WJC_METTL3_EV_vs_WT_F07.14265.14265.2 3.74E-07 14/32 F.ASSLVSGLNSSASEPAK[136.11].E "sp|Q86U44|MTA70_HUMAN,tr|F5H6D8|F5H6D8_HUMAN,tr|H0YFV6|H0YFV6_HUMAN,tr|B4DTN4|B4DTN4_HUMAN" 4 1611.8195 0.001 101342 14265 2 1611.818966 806.917 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 6.05 2528.6 - 620803 - - - -0.3499 - 2.978 0.596 - 546.6 1 1 0 -0.0006 17 0 0 0 0.00E+00 1.23E+07 - - - 6.1258 0.9992 221125_WJC_METTL3_EV_vs_WT_F07.14266.14266.4 0.000197 13/90 R.GTFHDDR[166.11]DDGVDYWAK[136.11].R "tr|H0YF63|H0YF63_HUMAN,tr|E9PK91|E9PK91_HUMAN" 2 1913.8299 1.56 101343 14266 4 1913.835047 479.4648 Bcl-2-associated transcription factor 1 (Fragment) OS=Homo sapiens OX=9606 GN=BCLAF1 PE=1 SV=1 4.28 2528.7 - 555739 - - - 2.6763 - 2.178 0.438 - 89.6 1 2 1 0.0051 16 0 0 0 1.58E+07 1.01E+07 - - - 3.3111 0.9997 221125_WJC_METTL3_EV_vs_WT_F07.14267.14267.4 0.00159 13/84 K.NILLVHYNSVSHLHK.M "sp|Q9C0A1|ZFHX2_HUMAN,sp|Q86UP3|ZFHX4_HUMAN,sp|Q15911|ZFHX3_HUMAN,tr|A0A494BZV7|A0A494BZV7_HUMAN,tr|E5RI93|E5RI93_HUMAN,tr|E7EVZ1|E7EVZ1_HUMAN" 6 1772.9686 3.15 101344 14267 4 1772.969903 444.2494 Zinc finger homeobox protein 2 OS=Homo sapiens OX=9606 GN=ZFHX2 PE=1 SV=3 8.61 2528.8 - 548018 - - - 0.7417 - 2.03 0.354 - 65.7 1 2 0 0.0013 15 0 0 0 7.69E+06 2.44E+06 - - - 2.5602 0.9997 221125_WJC_METTL3_EV_vs_WT_F07.14268.14268.3 5.64E-08 15/56 K.ILQINK[136.11]DDVTALHC[160.03]K[136.11].V "sp|O76094|SRP72_HUMAN,tr|R4GNC1|R4GNC1_HUMAN,tr|D6RDY6|D6RDY6_HUMAN" 3 1782.9633 0.47 101345 14268 3 1782.968238 595.3284 Signal recognition particle subunit SRP72 OS=Homo sapiens OX=9606 GN=SRP72 PE=1 SV=3 6.74 2529 - 545465 - - - 2.7667 - 2.698 0.514 - 214.1 1 2 1 0.0049 15 0 0 0 3.19E+06 6.81E+06 - - - 6.859 1 221125_WJC_METTL3_EV_vs_WT_F07.14269.14269.3 4.11E-06 16/64 K.SQLLSNHQQQLQADSFK[136.11].A sp|Q9ULD9|ZN608_HUMAN 1 1978.9952 3.29 101346 14269 3 1978.995291 660.6723 Zinc finger protein 608 OS=Homo sapiens OX=9606 GN=ZNF608 PE=1 SV=4 6.46 2529.1 - 482630 - - - 0.0445 - 3.06 0.486 - 304.3 1 2 0 0.0001 17 0 0 0 1.19E+07 3.61E+06 - - - 6.7838 0.9995 221125_WJC_METTL3_EV_vs_WT_F07.14270.14270.3 4.37E-07 16/60 R.GTFHDDRDDGVDYWAK.R "tr|H0YF63|H0YF63_HUMAN,tr|E9PK91|E9PK91_HUMAN" 2 1895.8075 1.46 101347 14270 3 1895.801428 632.9431 Bcl-2-associated transcription factor 1 (Fragment) OS=Homo sapiens OX=9606 GN=BCLAF1 PE=1 SV=1 4.28 2529.2 - 685968 - - - -3.1791 - 2.662 0.519 - 243.6 1 2 1 -0.006 16 0 0 0 1.31E+07 8.97E+06 - - - 6.8368 0.9995 221125_WJC_METTL3_EV_vs_WT_F07.14271.14271.3 0.0153 Sep-48 R.SIFQHIQSAQSQR.S "sp|Q9Y2W1|TR150_HUMAN,tr|A0A3B3ITZ9|A0A3B3ITZ9_HUMAN" 2 1528.7746 2.72 101348 14271 3 1528.775496 510.5988 Thyroid hormone receptor-associated protein 3 OS=Homo sapiens OX=9606 GN=THRAP3 PE=1 SV=2 9.49 2529.3 - 452885 - - - 0.5606 - 1.817 0.327 - 77.2 1 2 0 0.0009 13 0 0 0 4.29E+07 1.58E+07 - - - 3.8046 1 221125_WJC_METTL3_EV_vs_WT_F07.14272.14272.2 5.30E-09 14/32 K.LNQVC[160.03]FDDDGTSSPQDR[166.11].L "sp|Q8N1F7|NUP93_HUMAN,tr|H3BPA9|H3BPA9_HUMAN,tr|H3BVG0|H3BVG0_HUMAN" 3 1962.8253 2.49 101349 14272 2 1962.824598 982.4199 Nuclear pore complex protein Nup93 OS=Homo sapiens OX=9606 GN=NUP93 PE=1 SV=2 3.77 2529.4 - 421510 - - - -0.3597 - 3.075 0.691 - 642.7 1 2 0 -0.0007 17 0 0 0 1.57E+07 6.31E+06 - - - 6.9062 0.9999 221125_WJC_METTL3_EV_vs_WT_F07.14278.14278.3 0.00022 17/64 K.MAPVPLDDSNR[166.11]PASLTK[136.11].D "sp|Q9NYF8|BCLF1_HUMAN,tr|E9PKI6|E9PKI6_HUMAN,tr|A0A1W2PQ43|A0A1W2PQ43_HUMAN,tr|E9PK91|E9PK91_HUMAN,tr|E9PJA7|E9PJA7_HUMAN,tr|E9PK09|E9PK09_HUMAN,tr|E9PQN2|E9PQN2_HUMAN" 7 1828.9472 2.52 101353 14278 3 1828.943253 610.6563 Bcl-2-associated transcription factor 1 OS=Homo sapiens OX=9606 GN=BCLAF1 PE=1 SV=2 5.71 2530 - 2.02E+06 - - - -2.1603 - 2.73 0.453 - 274.4 1 2 0 -0.004 17 0 0 0 9.93E+07 3.94E+07 - - - 6.1266 1 221125_WJC_METTL3_EV_vs_WT_F07.14280.14280.3 2.99E-07 17/64 R.AQVQEFC[160.03]DYGTK[136.11]EEC[160.03]MK[136.11].A "sp|Q86U44|MTA70_HUMAN,tr|H0YFV6|H0YFV6_HUMAN" 2 2137.909 1.09 101355 14280 3 2137.906381 713.6436 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 4.41 2530.2 - 1.36E+06 - - - -1.2077 - 3.765 0.638 - 278.3 1 2 1 -0.0026 17 0 0 0 1.10E+08 1.01E+08 - - - 9.0016 0.9997 221125_WJC_METTL3_EV_vs_WT_F07.14281.14281.4 0.000107 16/84 K.ILQINKDDVTALHC[160.03]K.V "sp|O76094|SRP72_HUMAN,tr|R4GNC1|R4GNC1_HUMAN,tr|D6RDY6|D6RDY6_HUMAN" 3 1766.9349 0.47 101356 14281 4 1766.934336 442.741 Signal recognition particle subunit SRP72 OS=Homo sapiens OX=9606 GN=SRP72 PE=1 SV=3 6.74 2530.3 - 831743 - - - -0.322 - 2.619 0.442 - 220.4 1 2 1 -0.0006 15 0 0 0 6.05E+06 1.28E+07 - - - 3.4175 0.9999 221125_WJC_METTL3_EV_vs_WT_F07.14283.14283.4 1.48E-05 14/96 K.LAASIAPEIYGHEDVK[136.11]K[136.11].A sp|P33993|MCM7_HUMAN 1 1856.0015 0.97 101358 14283 4 1856.003248 465.0076 DNA replication licensing factor MCM7 OS=Homo sapiens OX=9606 GN=MCM7 PE=1 SV=4 5.45 2530.5 - 657306 - - - 0.9612 - 3.131 0.398 - 148.4 1 2 0 0.0018 17 0 0 0 6.76E+06 7.00E+06 - - - 3.086 0.9916 221125_WJC_METTL3_EV_vs_WT_F07.14284.14284.3 0.0132 Oct-52 R.NLLFQDC[160.03]EK[136.11]EQDNK[136.11].T sp|Q8WWK9|CKAP2_HUMAN 1 1795.8382 0.59 101359 14284 3 1795.833395 599.62 Cytoskeleton-associated protein 2 OS=Homo sapiens OX=9606 GN=CKAP2 PE=1 SV=1 4.32 2530.7 - 595396 - - - -2.6556 - 1.795 0.318 - 87.6 1 2 1 -0.0048 14 0 0 0 1.05E+07 1.79E+07 - - - 3.6387 0.9991 221125_WJC_METTL3_EV_vs_WT_F07.14287.14287.4 3.13E-05 16/102 R.GPALTPIR[166.11]DEEWGGHSPR[166.11].S "sp|Q86X29|LSR_HUMAN,tr|S4R3V8|S4R3V8_HUMAN" 2 1993.9873 1.48 101362 14287 4 1993.986182 499.5041 Lipolysis-stimulated lipoprotein receptor OS=Homo sapiens OX=9606 GN=LSR PE=1 SV=4 5.45 2531.1 - 280651 - - - -0.5672 - 2.903 0.36 - 194.7 1 2 1 -0.0011 18 0 0 0 4.18E+06 2.83E+06 - - - 2.7242 0.9999 221125_WJC_METTL3_EV_vs_WT_F07.14293.14293.3 0.00124 13/44 R.VC[160.03]EEIAIIPSKK.L "sp|P08708|RS17_HUMAN,tr|H0YN73|H0YN73_HUMAN,tr|H3BNC9|H3BNC9_HUMAN,tr|H0YN88|H0YN88_HUMAN,tr|A0A075B716|A0A075B716_HUMAN" 5 1385.7588 1.38 101366 14293 3 1385.760792 462.9269 40S ribosomal protein S17 OS=Homo sapiens OX=9606 GN=RPS17 PE=1 SV=2 6.11 2531.8 - 1.49E+06 - - - 1.4101 - 2.486 0.455 - 242.2 1 2 0 0.002 12 0 0 0 1.49E+07 1.08E+07 - - - 6.1365 1 221125_WJC_METTL3_EV_vs_WT_F07.14294.14294.3 1.52E-09 19/56 K.K[136.11]AQEGGGSEVFQELK[136.11].G "sp|Q8NCA5|FA98A_HUMAN,tr|E9PH82|E9PH82_HUMAN" 2 1621.8283 1.55 101367 14294 3 1621.82878 541.6167 Protein FAM98A OS=Homo sapiens OX=9606 GN=FAM98A PE=1 SV=2 4.79 2531.9 - 1.14E+06 - - - 0.3262 - 3.346 0.596 - 520.6 1 2 0 0.0005 15 0 0 0 1.75E+07 1.13E+07 - - - 8.3362 1 221125_WJC_METTL3_EV_vs_WT_F07.14297.14297.4 1.45E-08 15/78 R.K[136.11]VVVVVPNEEDWK[136.11]K[136.11].R "sp|Q1KMD3|HNRL2_HUMAN,tr|H3BQZ7|H3BQZ7_HUMAN" 2 1691.9673 1.73 101370 14297 4 1691.967582 423.9991 Heterogeneous nuclear ribonucleoprotein U-like protein 2 OS=Homo sapiens OX=9606 GN=HNRNPUL2 PE=1 SV=1 6.18 2532.3 - 623148 - - - 0.1921 - 2.76 0.58 - 236.1 1 2 0 0.0003 14 0 0 0 2.06E+07 1.19E+07 - - - 4.6437 1 221125_WJC_METTL3_EV_vs_WT_F07.14298.14298.2 1.50E-07 26-Nov R.QRPSEIKDYSPYFK.T sp|P08779|K1C16_HUMAN 1 1756.8784 999 101371 14298 2 1756.88023 879.4465 "Keratin, type I cytoskeletal 16 OS=Homo sapiens OX=9606 GN=KRT16 PE=1 SV=4" 8.43 2532.5 - 568681 - - - 1.0217 - 2.791 0.588 - 276.9 1 2 1 0.0018 14 0 0 0 7.37E+06 0.00E+00 - - - 5.9591 0.9963 221125_WJC_METTL3_EV_vs_WT_F07.14300.14300.3 3.12E-05 Sep-56 K.ILQINKDDVTALHC[160.03]K.V "sp|O76094|SRP72_HUMAN,tr|R4GNC1|R4GNC1_HUMAN,tr|D6RDY6|D6RDY6_HUMAN" 3 1766.9349 0.47 101373 14300 3 1766.93049 589.9856 Signal recognition particle subunit SRP72 OS=Homo sapiens OX=9606 GN=SRP72 PE=1 SV=3 6.74 2532.7 - 374693 - - - -2.4987 - 1.954 0.351 - 95.3 1 2 1 -0.0044 15 0 0 0 3.19E+06 6.81E+06 - - - 4.2 1 221125_WJC_METTL3_EV_vs_WT_F07.14306.14306.3 1.62E-06 17/52 R.KVVVVVPNEEDWKK.R "sp|Q1KMD3|HNRL2_HUMAN,tr|H3BQZ7|H3BQZ7_HUMAN" 2 1667.9247 1.03 101377 14306 3 1667.923293 556.9822 Heterogeneous nuclear ribonucleoprotein U-like protein 2 OS=Homo sapiens OX=9606 GN=HNRNPUL2 PE=1 SV=1 6.18 2533.4 - 1.13E+06 - - - -0.8178 - 2.57 0.528 - 454 1 2 0 -0.0014 14 0 0 0 1.71E+07 1.66E+07 - - - 6.9348 0.9999 221125_WJC_METTL3_EV_vs_WT_F07.14307.14307.3 1.12E-06 18/68 R.LSTPSSVTK[136.11]PANSVFTTK[136.11].W "sp|Q7Z2W4|ZCCHV_HUMAN,tr|H7C5K1|H7C5K1_HUMAN,tr|C9J6P4|C9J6P4_HUMAN,tr|A0A7P0T8C6|A0A7P0T8C6_HUMAN" 4 1880.0226 0.94 101378 14307 3 1880.028578 627.6815 Zinc finger CCCH-type antiviral protein 1 OS=Homo sapiens OX=9606 GN=ZC3HAV1 PE=1 SV=3 10 2533.5 - 1.09E+06 - - - 3.1835 - 3.382 0.554 - 425.4 1 2 0 0.006 18 0 0 0 1.34E+07 1.42E+07 - - - 7.749 0.9999 221125_WJC_METTL3_EV_vs_WT_F07.14311.14311.4 3.74E-09 16/84 R.GC[160.03]GVVEFK[136.11]DEEFVK[136.11]K[136.11].A "sp|Q9P2K5|MYEF2_HUMAN,tr|A0A0A0MR39|A0A0A0MR39_HUMAN,tr|A0A0A0MQW0|A0A0A0MQW0_HUMAN" 3 1793.9084 1.05 101382 14311 4 1793.906411 449.4844 Myelin expression factor 2 OS=Homo sapiens OX=9606 GN=MYEF2 PE=1 SV=3 4.87 2534 - 373318 - - - -1.121 - 3.301 0.605 - 160.2 1 2 1 -0.002 15 0 0 0 4.53E+07 4.32E+07 - - - 4.9187 0.9998 221125_WJC_METTL3_EV_vs_WT_F07.14315.14315.3 6.92E-05 Nov-56 K.TK[136.11]PYIQVDIGGGQTK[136.11].T "sp|P11021|BIP_HUMAN,tr|A0A7P0TB36|A0A7P0TB36_HUMAN,tr|A0A7P0TAI0|A0A7P0TAI0_HUMAN" 3 1619.8854 0.54 101384 14315 3 1619.885555 540.9691 Endoplasmic reticulum chaperone BiP OS=Homo sapiens OX=9606 GN=HSPA5 PE=1 SV=2 8.17 2534.4 - 1.95E+06 - - - 0.113 - 2.183 0.368 - 140.7 1 2 0 0.0002 15 0 0 0 1.61E+08 2.96E+08 - - - 4.6799 0.9981 221125_WJC_METTL3_EV_vs_WT_F07.14316.14316.3 0.000668 13/44 R.SMQDVVEDFKNK.Y sp|P08729|K2C7_HUMAN 1 1438.6762 192.29 101385 14316 3 1438.675682 480.566 "Keratin, type II cytoskeletal 7 OS=Homo sapiens OX=9606 GN=KRT7 PE=1 SV=5" 4.56 2534.6 - 1.46E+06 - - - -0.3809 - 2.26 0.284 - 210.2 1 2 1 -0.0005 12 0 0 0 3.24E+07 1.69E+05 - - - 3.9662 1 221125_WJC_METTL3_EV_vs_WT_F07.14318.14318.3 2.76E-06 15/56 K.KAQEGGGSEVFQELK.G "sp|Q8NCA5|FA98A_HUMAN,tr|E9PH82|E9PH82_HUMAN" 2 1605.7999 1.55 101387 14318 3 1605.800001 536.2739 Protein FAM98A OS=Homo sapiens OX=9606 GN=FAM98A PE=1 SV=2 4.79 2534.7 - 1.50E+06 - - - 0.0934 - 2.511 0.467 - 313.2 1 2 0 0.0001 15 0 0 0 1.75E+07 1.13E+07 - - - 6.1489 0.9996 221125_WJC_METTL3_EV_vs_WT_F07.14320.14320.3 0.000727 Nov-64 K.SSTKPAAGGTAPLPPWK.S "sp|Q15942|ZYX_HUMAN,tr|H7C3D3|H7C3D3_HUMAN,tr|H0Y2Y8|H0Y2Y8_HUMAN,tr|H7C3R3|H7C3R3_HUMAN" 4 1664.8886 3.14 101389 14320 3 1664.888201 555.9701 Zyxin OS=Homo sapiens OX=9606 GN=ZYX PE=1 SV=1 10 2534.9 - 1.20E+06 - - - -0.2433 - 2.002 0.34 - 82.5 1 2 0 -0.0004 17 0 0 0 1.15E+07 3.67E+06 - - - 4.0842 0.9999 221125_WJC_METTL3_EV_vs_WT_F07.14321.14321.3 1.03E-09 20/68 R.LSTPSSVTKPANSVFTTK.W "sp|Q7Z2W4|ZCCHV_HUMAN,tr|H7C5K1|H7C5K1_HUMAN,tr|C9J6P4|C9J6P4_HUMAN,tr|A0A7P0T8C6|A0A7P0T8C6_HUMAN" 4 1863.9942 0.94 101390 14321 3 1864.001108 622.3387 Zinc finger CCCH-type antiviral protein 1 OS=Homo sapiens OX=9606 GN=ZC3HAV1 PE=1 SV=3 10 2535 - 844444 - - - 3.7098 - 4.15 0.53 - 411 1 2 0 0.0069 18 0 0 0 1.34E+07 1.42E+07 - - - 7.9907 0.9999 221125_WJC_METTL3_EV_vs_WT_F07.14322.14322.4 4.70E-07 16/84 R.GC[160.03]GVVEFKDEEFVKK.A "sp|Q9P2K5|MYEF2_HUMAN,tr|A0A0A0MR39|A0A0A0MR39_HUMAN,tr|A0A0A0MQW0|A0A0A0MQW0_HUMAN" 3 1769.8658 1.05 101391 14322 4 1769.865655 443.4737 Myelin expression factor 2 OS=Homo sapiens OX=9606 GN=MYEF2 PE=1 SV=3 4.87 2535.1 - 633021 - - - -0.0944 - 2.887 0.534 - 125.2 1 2 1 -0.0002 15 0 0 0 4.53E+07 4.32E+07 - - - 4.2532 1 221125_WJC_METTL3_EV_vs_WT_F07.14323.14323.3 2.91E-08 19/64 R.RC[160.03]VYTIPAHQNLVTGVK.F sp|O43172|PRP4_HUMAN 1 1955.0411 4.77 101392 14323 3 1955.04383 652.6876 U4\U6 small nuclear ribonucleoprotein Prp4 OS=Homo sapiens OX=9606 GN=PRPF4 PE=1 SV=2 9.31 2535.3 - 474239 - - - 1.3959 - 3.775 0.546 - 541.6 1 2 0 0.0027 17 0 0 0 1.21E+07 2.54E+06 - - - 7.9825 0.9999 221125_WJC_METTL3_EV_vs_WT_F07.14329.14329.3 7.09E-07 13/56 R.GC[160.03]GVVEFK[136.11]DEEFVK[136.11]K[136.11].A "sp|Q9P2K5|MYEF2_HUMAN,tr|A0A0A0MR39|A0A0A0MR39_HUMAN,tr|A0A0A0MQW0|A0A0A0MQW0_HUMAN" 3 1793.9084 0.92 101396 14329 3 1793.909432 598.9768 Myelin expression factor 2 OS=Homo sapiens OX=9606 GN=MYEF2 PE=1 SV=3 4.87 2536.1 - 1.58E+06 - - - 0.563 - 2.535 0.572 - 154.1 1 2 1 0.001 15 0 0 0 3.16E+07 3.41E+07 - - - 7.3442 0.9999 221125_WJC_METTL3_EV_vs_WT_F07.14330.14330.3 4.55E-06 15/52 R.NLLFQDC[160.03]EKEQDNK.T sp|Q8WWK9|CKAP2_HUMAN 1 1779.8098 0.59 101397 14330 3 1779.80705 594.2772 Cytoskeleton-associated protein 2 OS=Homo sapiens OX=9606 GN=CKAP2 PE=1 SV=1 4.32 2536.2 - 1.24E+06 - - - -1.5249 - 2.941 0.56 - 220.4 1 2 1 -0.0027 14 0 0 0 1.04E+07 1.76E+07 - - - 7.6495 0.9999 221125_WJC_METTL3_EV_vs_WT_F07.14332.14332.3 2.62E-05 15/56 R.GC[160.03]GVVEFKDEEFVKK.A "sp|Q9P2K5|MYEF2_HUMAN,tr|A0A0A0MR39|A0A0A0MR39_HUMAN,tr|A0A0A0MQW0|A0A0A0MQW0_HUMAN" 3 1769.8658 0.92 101399 14332 3 1769.864471 590.9626 Myelin expression factor 2 OS=Homo sapiens OX=9606 GN=MYEF2 PE=1 SV=3 4.87 2536.4 - 1.23E+06 - - - -0.7633 - 3.308 0.504 - 251.8 1 2 1 -0.0014 15 0 0 0 3.14E+07 3.41E+07 - - - 7.2804 1 221125_WJC_METTL3_EV_vs_WT_F07.14333.14333.3 3.50E-07 23/60 K.NQLTSNPENTVFDAK[136.11]R[166.11].L "sp|P11021|BIP_HUMAN,tr|A0A7P0TB36|A0A7P0TB36_HUMAN,tr|A0A7P0TAI0|A0A7P0TAI0_HUMAN" 3 1850.9242 0.56 101400 14333 3 1850.922149 617.982 Endoplasmic reticulum chaperone BiP OS=Homo sapiens OX=9606 GN=HSPA5 PE=1 SV=2 6.07 2536.5 - 1.04E+06 - - - -1.0865 - 3.56 0.564 - 785.3 1 2 0 -0.002 16 0 0 0 2.32E+07 4.12E+07 - - - 8.0855 0.9999 221125_WJC_METTL3_EV_vs_WT_F07.14337.14337.3 0.00187 Aug-40 K.HGFTILNSMHK[136.11].Y sp|Q13207|TBX2_HUMAN 1 1291.6587 1.11 101404 14337 3 1291.65816 431.5602 T-box transcription factor TBX2 OS=Homo sapiens OX=9606 GN=TBX2 PE=1 SV=3 8.76 2537 - 541023 - - - -0.3995 - 1.829 0.43 - 93.2 1 2 0 -0.0005 11 0 0 0 8.32E+06 7.47E+06 - - - 5.0491 0.9997 221125_WJC_METTL3_EV_vs_WT_F07.14342.14342.2 8.09E-06 28-Nov K.TK[136.11]PYIQVDIGGGQTK[136.11].T "sp|P11021|BIP_HUMAN,tr|A0A7P0TB36|A0A7P0TB36_HUMAN,tr|A0A7P0TAI0|A0A7P0TAI0_HUMAN" 3 1619.8854 0.49 101409 14342 2 1619.881769 810.95 Endoplasmic reticulum chaperone BiP OS=Homo sapiens OX=9606 GN=HSPA5 PE=1 SV=2 8.17 2537.7 - 319344 - - - -2.2242 - 2.525 0.524 - 267.1 1 2 0 -0.0036 15 0 0 0 6.89E+06 1.40E+07 - - - 5.1873 0.9999 221125_WJC_METTL3_EV_vs_WT_F07.14345.14345.4 1.37E-06 24/102 R.ILENEKDLEEAEEYKEAR.L "sp|O75347|TBCA_HUMAN,tr|E5RIW3|E5RIW3_HUMAN,tr|E5RJD8|E5RJD8_HUMAN,tr|E5RHG6|E5RHG6_HUMAN" 4 2207.0594 0.32 101410 14345 4 2207.06136 552.7721 Tubulin-specific chaperone A OS=Homo sapiens OX=9606 GN=TBCA PE=1 SV=3 4.22 2538.1 - 1.65E+06 - - - 0.9003 - 4.245 0.533 - 607.9 1 2 2 0.002 18 0 0 0 1.21E+07 3.78E+07 - - - 4.3599 0.8499 221125_WJC_METTL3_EV_vs_WT_F07.14346.14346.3 3.55E-07 18/72 R.TSFTSVSRSGGGGGGGFGR.V "sp|P13647|K2C5_HUMAN,tr|F8VV57|F8VV57_HUMAN,tr|F8VU69|F8VU69_HUMAN" 3 1729.8132 2.23 101411 14346 3 1730.803981 577.6117 "Keratin, type II cytoskeletal 5 OS=Homo sapiens OX=9606 GN=KRT5 PE=1 SV=3" 12 2538.1 - 1.25E+06 - - - 572.7624 - 3.097 0.556 - 311.5 1 2 1 0.9908 19 0 0 0 2.28E+06 1.02E+06 - - - 7.2417 1 221125_WJC_METTL3_EV_vs_WT_F07.14347.14347.4 1.91E-05 19/102 R.EAHSPGPLVKPFETASVK.S "sp|P35548|MSX2_HUMAN,tr|D6RIS4|D6RIS4_HUMAN" 2 1892.9996 0.13 101412 14347 4 1893.001713 474.2572 Homeobox protein MSX-2 OS=Homo sapiens OX=9606 GN=MSX2 PE=1 SV=3 6.85 2538.2 - 1.17E+06 - - - 1.1094 - 2.834 0.489 - 272.6 1 2 0 0.0021 18 0 0 0 5.37E+07 4.05E+08 - - - 3.8385 1 221125_WJC_METTL3_EV_vs_WT_F07.14350.14350.3 2.25E-07 14/52 R.K[136.11]VVVVVPNEEDWK[136.11]K[136.11].R "sp|Q1KMD3|HNRL2_HUMAN,tr|H3BQZ7|H3BQZ7_HUMAN" 2 1691.9673 1.03 101415 14350 3 1691.969793 564.9964 Heterogeneous nuclear ribonucleoprotein U-like protein 2 OS=Homo sapiens OX=9606 GN=HNRNPUL2 PE=1 SV=1 6.18 2538.6 - 631106 - - - 1.4988 - 2.487 0.5 - 292.3 1 2 0 0.0025 14 0 0 0 1.72E+07 1.66E+07 - - - 6.535 0.9999 221125_WJC_METTL3_EV_vs_WT_F07.14353.14353.3 3.07E-05 16/56 K.EFEDDLVK[136.11]ESSSC[160.03]GK[136.11].D "sp|O43148|MCES_HUMAN,tr|K7EPP5|K7EPP5_HUMAN" 2 1744.7796 1.5 101418 14353 3 1744.777114 582.6005 mRNA cap guanine-N7 methyltransferase OS=Homo sapiens OX=9606 GN=RNMT PE=1 SV=1 4.18 2539 - 404214 - - - -1.4512 - 2.896 0.592 - 318.8 1 2 1 -0.0025 15 0 0 0 5.51E+06 3.68E+06 - - - 7.9141 0.9998 221125_WJC_METTL3_EV_vs_WT_F07.14354.14354.2 0.00158 13/28 K.TKPYIQVDIGGGQTK.T "sp|P11021|BIP_HUMAN,tr|A0A7P0TB36|A0A7P0TB36_HUMAN,tr|A0A7P0TAI0|A0A7P0TAI0_HUMAN" 3 1603.857 0.49 101419 14354 2 1603.856989 802.9358 Endoplasmic reticulum chaperone BiP OS=Homo sapiens OX=9606 GN=HSPA5 PE=1 SV=2 8.17 2539.1 - 404049 - - - 0.0106 - 2.207 0.444 - 406 1 2 0 0 15 0 0 0 6.89E+06 1.40E+07 - - - 4.2666 0.9999 221125_WJC_METTL3_EV_vs_WT_F07.14355.14355.3 1.13E-07 14/96 K.ADGLGGK[136.11]GEPGGGPGELAPVGPDEK[136.11].E sp|P55316|FOXG1_HUMAN 1 2276.1256 1.02 101420 14355 3 2276.12415 759.7158 Forkhead box protein G1 OS=Homo sapiens OX=9606 GN=FOXG1 PE=1 SV=2 4.18 2539.3 - 304660 - - - -0.6173 - 2.945 0.574 - 133.3 1 2 1 -0.0014 25 0 0 0 3.39E+06 3.32E+06 - - - 7.4241 0.9859 221125_WJC_METTL3_EV_vs_WT_F07.14358.14358.3 0.00737 Nov-44 R.DADETKEWIEEK.N "sp|Q13813|SPTN1_HUMAN,tr|A0A0D9SF54|A0A0D9SF54_HUMAN,tr|A0A0D9SGF6|A0A0D9SGF6_HUMAN" 3 1491.6729 1.03 101423 14358 3 1491.679485 498.2316 "Spectrin alpha chain, non-erythrocytic 1 OS=Homo sapiens OX=9606 GN=SPTAN1 PE=1 SV=3" 4.08 2539.7 - 234784 - - - 4.4018 - 2.235 0.313 - 145.8 1 2 1 0.0066 12 0 0 0 2.28E+06 2.21E+06 - - - 4.2571 0.9992 221125_WJC_METTL3_EV_vs_WT_F07.14360.14360.3 0.0327 Aug-32 K.ELWDQFHK[136.11]R[166.11].G sp|O15119|TBX3_HUMAN 1 1275.6479 0.49 101425 14360 3 1275.648154 426.2233 T-box transcription factor TBX3 OS=Homo sapiens OX=9606 GN=TBX3 PE=1 SV=4 6.85 2539.9 - 201765 - - - 0.1795 - 1.841 0.277 - 109.5 1 2 0 0.0002 9 0 0 0 1.13E+06 2.30E+06 - - - 3.4676 0.9999 221125_WJC_METTL3_EV_vs_WT_F07.14364.14364.4 0.000285 13/78 R.INSYGYGDHYIHIK[136.11].L sp|Q96EY1|DNJA3_HUMAN 1 1686.8246 1.16 101427 14364 4 1686.824827 422.7134 "DnaJ homolog subfamily A member 3, mitochondrial OS=Homo sapiens OX=9606 GN=DNAJA3 PE=1 SV=2" 6.92 2540.5 - 751806 - - - 0.1607 - 2.53 0.457 - 103.7 1 2 0 0.0003 14 0 0 0 7.63E+06 6.59E+06 - - - 3.5415 0.9992 221125_WJC_METTL3_EV_vs_WT_F07.14365.14365.3 0.000949 Nov-40 K.HGFTILNSMHK.Y sp|Q13207|TBX2_HUMAN 1 1283.6445 1.1 101428 14365 3 1283.64732 428.8888 T-box transcription factor TBX2 OS=Homo sapiens OX=9606 GN=TBX2 PE=1 SV=3 8.76 2540.6 - 650357 - - - 2.2156 - 1.761 0.355 - 182.7 1 2 0 0.0028 11 0 0 0 8.18E+06 7.47E+06 - - - 4.1047 0.9347 221125_WJC_METTL3_EV_vs_WT_F07.14368.14368.2 0.0112 28-Jul R.R[166.11]AEQDSTTVAAFASS.L "sp|Q86U44|MTA70_HUMAN,tr|F5H6D8|F5H6D8_HUMAN,tr|H0YFV6|H0YFV6_HUMAN,tr|B4DTN4|B4DTN4_HUMAN" 4 1549.7248 0.001 101431 14368 2 1549.722228 775.8697 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 4.37 2541 - 257900 - - - -1.65 - 1.422 0.381 - 87.9 1 1 0 -0.0026 15 0 0 0 0.00E+00 7.43E+06 - - - 2.7198 1 221125_WJC_METTL3_EV_vs_WT_F07.14373.14373.3 1.82E-07 13/60 K.NQLTSNPENTVFDAKR.L "sp|P11021|BIP_HUMAN,tr|A0A7P0TB36|A0A7P0TB36_HUMAN,tr|A0A7P0TAI0|A0A7P0TAI0_HUMAN" 3 1832.9017 0.56 101434 14373 3 1832.905941 611.9745 Endoplasmic reticulum chaperone BiP OS=Homo sapiens OX=9606 GN=HSPA5 PE=1 SV=2 6.07 2541.6 - 2.42E+06 - - - 2.3193 - 2.945 0.562 - 259.7 1 2 0 0.0043 16 0 0 0 2.32E+07 4.15E+07 - - - 7.576 1 221125_WJC_METTL3_EV_vs_WT_F07.14375.14375.3 7.67E-07 18/68 R.EAHSPGPLVKPFETASVK.S "sp|P35548|MSX2_HUMAN,tr|D6RIS4|D6RIS4_HUMAN" 2 1892.9996 1.22 101436 14375 3 1893.003242 632.0071 Homeobox protein MSX-2 OS=Homo sapiens OX=9606 GN=MSX2 PE=1 SV=3 6.85 2541.8 - 1.24E+06 - - - 1.9171 - 2.954 0.517 - 360.7 1 2 0 0.0036 18 0 0 0 2.27E+07 1.86E+07 - - - 7.0002 0.8645 221125_WJC_METTL3_EV_vs_WT_F07.14377.14377.3 0.00186 13/68 Y.YISTQQAPSEADLEQYKK.A "sp|Q8WVM8|SCFD1_HUMAN,tr|A0A7I2V4U2|A0A7I2V4U2_HUMAN,tr|A0A7I2V4B8|A0A7I2V4B8_HUMAN,tr|H0YIZ7|H0YIZ7_HUMAN,tr|A0A7I2V5Z4|A0A7I2V5Z4_HUMAN,tr|B7Z5N7|B7Z5N7_HUMAN,tr|A0A7I2V5I2|A0A7I2V5I2_HUMAN,tr|A0A7I2V590|A0A7I2V590_HUMAN,tr|A0A7I2V2U5|A0A7I2V2U5_HUMAN,tr|A0A7I2V448|A0A7I2V448_HUMAN,tr|A0A7I2V320|A0A7I2V320_HUMAN,tr|A0A7I2V3G4|A0A7I2V3G4_HUMAN,tr|A0A7I2V3B4|A0A7I2V3B4_HUMAN,tr|G3V2M8|G3V2M8_HUMAN,tr|A0A7I2V4R0|A0A7I2V4R0_HUMAN" 15 2098.0219 1.4 101438 14377 3 2098.029004 700.3479 Sec1 family domain-containing protein 1 OS=Homo sapiens OX=9606 GN=SCFD1 PE=1 SV=4 4.68 2542 - 687216 - - - 3.4027 - 2.392 0.318 - 133.2 1 1 0 0.0071 18 0 0 0 6.01E+06 4.28E+06 - - - 4.2551 0.9959 221125_WJC_METTL3_EV_vs_WT_F07.14379.14379.3 6.80E-08 14/68 Y.YISTQQAPSEADLEQYK[136.11]K[136.11].A "sp|Q8WVM8|SCFD1_HUMAN,tr|A0A7I2V4U2|A0A7I2V4U2_HUMAN,tr|A0A7I2V4B8|A0A7I2V4B8_HUMAN,tr|H0YIZ7|H0YIZ7_HUMAN,tr|A0A7I2V5Z4|A0A7I2V5Z4_HUMAN,tr|B7Z5N7|B7Z5N7_HUMAN,tr|A0A7I2V5I2|A0A7I2V5I2_HUMAN,tr|A0A7I2V590|A0A7I2V590_HUMAN,tr|A0A7I2V2U5|A0A7I2V2U5_HUMAN,tr|A0A7I2V448|A0A7I2V448_HUMAN,tr|A0A7I2V320|A0A7I2V320_HUMAN,tr|A0A7I2V3G4|A0A7I2V3G4_HUMAN,tr|A0A7I2V3B4|A0A7I2V3B4_HUMAN,tr|G3V2M8|G3V2M8_HUMAN,tr|A0A7I2V4R0|A0A7I2V4R0_HUMAN" 15 2114.0503 1.4 101440 14379 3 2114.053045 705.6907 Sec1 family domain-containing protein 1 OS=Homo sapiens OX=9606 GN=SCFD1 PE=1 SV=4 4.68 2542.2 - 490116 - - - 1.315 - 2.848 0.481 - 146.4 1 1 0 0.0028 18 0 0 0 6.01E+06 4.28E+06 - - - 6.5081 0.9998 221125_WJC_METTL3_EV_vs_WT_F07.14380.14380.4 2.98E-06 15/72 K.LK[136.11]DVLLQVDDER[166.11]R[166.11].N sp|P35579|MYH9_HUMAN 1 1625.9095 1.01 101441 14380 4 1625.910661 407.4847 Myosin-9 OS=Homo sapiens OX=9606 GN=MYH9 PE=1 SV=4 4.68 2542.4 - 433933 - - - 0.7079 - 2.727 0.447 - 344.2 1 2 1 0.0012 13 0 0 0 5.34E+06 5.28E+06 - - - 3.4883 0.99 221125_WJC_METTL3_EV_vs_WT_F07.14381.14381.2 8.93E-07 24-Nov R.IEDVTPIPSDSTR[166.11].R "sp|P62263|RS14_HUMAN,tr|A0A2R8Y811|A0A2R8Y811_HUMAN" 2 1438.7179 3.88 101442 14381 2 1438.728606 720.3662 40S ribosomal protein S14 OS=Homo sapiens OX=9606 GN=RPS14 PE=1 SV=3 4.03 2542.5 - 378031 - - - 7.4351 - 2.31 0.504 - 333.5 1 2 0 0.0107 13 0 0 0 9.76E+06 2.52E+06 - - - 4.909 1 221125_WJC_METTL3_EV_vs_WT_F07.14382.14382.2 3.23E-09 15/32 Y.VHYEIDAC[160.03]MDSEAPGSK[136.11].D "sp|Q86U44|MTA70_HUMAN,tr|H0YFV6|H0YFV6_HUMAN" 2 1915.8172 0.001 101443 14382 2 1915.818736 958.9159 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 4.31 2542.6 - 339092 - - - 0.8205 - 3.029 0.741 - 418.6 1 1 0 0.0016 17 0 0 0 0.00E+00 5.83E+07 - - - 7.2382 0.9919 221125_WJC_METTL3_EV_vs_WT_F07.14384.14384.4 6.20E-06 14/72 K.LKDVLLQVDDERR.N sp|P35579|MYH9_HUMAN 1 1597.8788 1.04 101445 14384 4 1597.888179 400.477 Myosin-9 OS=Homo sapiens OX=9606 GN=MYH9 PE=1 SV=4 4.68 2542.9 - 321609 - - - 5.8884 - 2.705 0.427 - 271.2 1 2 1 0.0094 13 0 0 0 5.47E+06 5.28E+06 - - - 3.309 0.9994 221125_WJC_METTL3_EV_vs_WT_F07.14389.14389.3 3.26E-05 Oct-40 K.MK[136.11]EIAEAYLGK[136.11].T "sp|P11142|HSP7C_HUMAN,tr|E9PQQ4|E9PQQ4_HUMAN,tr|E9PKE3|E9PKE3_HUMAN,tr|E9PN89|E9PN89_HUMAN,tr|E9PLF4|E9PLF4_HUMAN,tr|E9PI65|E9PI65_HUMAN,tr|E9PK54|E9PK54_HUMAN,tr|E9PPY6|E9PPY6_HUMAN,tr|E9PQK7|E9PQK7_HUMAN" 9 1267.6817 0.16 101448 14389 3 1267.683588 423.5678 Heat shock cognate 71 kDa protein OS=Homo sapiens OX=9606 GN=HSPA8 PE=1 SV=1 5.9 2543.6 - 829417 - - - 1.4814 - 2.333 0.383 - 143.5 1 2 1 0.0019 11 0 0 0 1.46E+06 9.16E+06 - - - 5.2162 0.9872 221125_WJC_METTL3_EV_vs_WT_F07.14390.14390.3 0.114 Nov-36 R.R[166.11]K[136.11]PFYPALIR[166.11].Y "sp|O00746|NDKM_HUMAN,tr|Q4TT34|Q4TT34_HUMAN,tr|H0Y6J0|H0Y6J0_HUMAN,tr|F2Z2X0|F2Z2X0_HUMAN,tr|A2IDC9|A2IDC9_HUMAN" 5 1287.781 1.83 101449 14390 3 1287.783826 430.2676 "Nucleoside diphosphate kinase, mitochondrial OS=Homo sapiens OX=9606 GN=NME4 PE=1 SV=1" 11 2543.7 - 615645 - - - 2.1929 - 1.579 0.203 - 175 1 2 0 0.0028 10 0 0 0 6.48E+07 3.54E+07 - - - 2.1365 0.9998 221125_WJC_METTL3_EV_vs_WT_F07.14391.14391.4 8.90E-05 18/102 R.EAHSPGPLVK[136.11]PFETASVK[136.11].S "sp|P35548|MSX2_HUMAN,tr|D6RIS4|D6RIS4_HUMAN" 2 1909.028 -1 101450 14391 4 1909.03284 478.2643 Homeobox protein MSX-2 OS=Homo sapiens OX=9606 GN=MSX2 PE=1 SV=3 6.85 2543.7 - 1.91E+06 - - - 2.5285 - 2.903 0.416 - 181.2 1 2 0 0.0048 18 0 0 0 0.00E+00 0.00E+00 - - - 3.2106 0.9997 221125_WJC_METTL3_EV_vs_WT_F07.14395.14395.3 7.17E-07 Oct-52 K.FDEK[136.11]ENVSNC[160.03]IQLK[136.11].T sp|Q9ULC4|MCTS1_HUMAN 1 1738.8531 1.07 101454 14395 3 1738.856296 580.625 Malignant T-cell-amplified sequence 1 OS=Homo sapiens OX=9606 GN=MCTS1 PE=1 SV=1 4.68 2544.1 - 527756 - - - 1.8466 - 2.264 0.486 - 87.8 1 2 1 0.0032 14 0 0 0 9.53E+06 8.89E+06 - - - 6.1291 0.9998 221125_WJC_METTL3_EV_vs_WT_F07.14397.14397.2 7.65E-06 14/32 R.AIGGGLSSVGGGSSTIK.Y "sp|P48668|K2C6C_HUMAN,sp|P02538|K2C6A_HUMAN" 2 1446.7678 999 101456 14397 2 1446.770405 724.3912 "Keratin, type II cytoskeletal 6C OS=Homo sapiens OX=9606 GN=KRT6C PE=1 SV=3" 8.8 2544.4 - 345730 - - - 1.7854 - 2.718 0.516 - 462.4 1 2 0 0.0026 17 0 0 0 5.77E+06 0.00E+00 - - - 5.3097 0.9998 221125_WJC_METTL3_EV_vs_WT_F07.14398.14398.3 1.24E-05 15/88 K.EATAQKPTGSVGSTVTTPPPLVR.G sp|Q86YP4|P66A_HUMAN 1 2293.2278 1.87 101457 14398 3 2293.234309 765.4165 Transcriptional repressor p66-alpha OS=Homo sapiens OX=9606 GN=GATAD2A PE=1 SV=1 8.85 2544.5 - 337127 - - - 2.8493 - 2.634 0.459 - 143.2 1 2 0 0.0065 23 0 0 0 3.12E+07 1.67E+07 - - - 5.9276 0.9998 221125_WJC_METTL3_EV_vs_WT_F07.14400.14400.4 8.56E-06 14/96 K.IQVHYYEDGNVQLVSHK.D "sp|P52907|CAZA1_HUMAN,sp|P47755|CAZA2_HUMAN" 2 2028.0065 1.8 101459 14400 4 2028.009419 508.0089 F-actin-capping protein subunit alpha-1 OS=Homo sapiens OX=9606 GN=CAPZA1 PE=1 SV=3 5.99 2544.8 - 319202 - - - 1.4448 - 2.837 0.379 - 161.1 1 2 0 0.0029 17 0 0 0 6.23E+06 3.46E+06 - - - 2.886 1 221125_WJC_METTL3_EV_vs_WT_F07.14401.14401.3 2.60E-06 14/60 R.QLQEERPELSESELTR.L "sp|P17480|UBF1_HUMAN,tr|E9PKP7|E9PKP7_HUMAN,tr|E9PLT2|E9PLT2_HUMAN" 3 1942.9596 1.42 101460 14401 3 1942.960663 648.6605 Nucleolar transcription factor 1 OS=Homo sapiens OX=9606 GN=UBTF PE=1 SV=1 4.33 2544.9 - 294251 - - - 0.5476 - 2.615 0.472 - 301.5 1 2 0 0.0011 16 0 0 0 2.13E+06 1.50E+06 - - - 6.2685 0.9981 221125_WJC_METTL3_EV_vs_WT_F07.14403.14403.3 0.000437 Sep-64 R.R[166.11]C[160.03]VYTIPAHQNLVTGVK[136.11].F sp|O43172|PRP4_HUMAN 1 1973.0636 5.72 101462 14403 3 1973.069347 658.6951 U4\U6 small nuclear ribonucleoprotein Prp4 OS=Homo sapiens OX=9606 GN=PRPF4 PE=1 SV=2 9.31 2545.2 - 238024 - - - 2.9274 - 1.949 0.319 - 96 1 2 0 0.0058 17 0 0 0 1.52E+07 2.67E+06 - - - 3.7808 0.9924 221125_WJC_METTL3_EV_vs_WT_F07.14404.14404.4 0.0437 Aug-72 R.MEDGHQMLTHWTR.K "sp|Q9Y4A5|TRRAP_HUMAN,tr|H0Y4W2|H0Y4W2_HUMAN,tr|F2Z2U4|F2Z2U4_HUMAN" 3 1640.7188 1.17 101463 14404 4 1640.722936 411.187 Transformation\transcription domain-associated protein OS=Homo sapiens OX=9606 GN=TRRAP PE=1 SV=3 5.95 2545.3 - 236092 - - - 2.533 - 1.622 0.248 - 64.3 1 2 0 0.0042 13 0 0 0 1.83E+06 1.57E+06 - - - 1.5628 0.8893 221125_WJC_METTL3_EV_vs_WT_F07.14406.14406.3 0.885 Aug-72 K.GDVEEDETIPDSEQDIR[166.11]PR[166.11].F "sp|Q92973|TNPO1_HUMAN,tr|A0A7P0T9C0|A0A7P0T9C0_HUMAN,tr|A0A7P0TBF0|A0A7P0TBF0_HUMAN,tr|A0A7P0T944|A0A7P0T944_HUMAN,tr|A0A7P0Z4D3|A0A7P0Z4D3_HUMAN" 5 2219.0093 0.88 101465 14406 3 2219.010044 740.677 Transportin-1 OS=Homo sapiens OX=9606 GN=TNPO1 PE=1 SV=2 3.85 2545.6 - 207007 - - - 0.3398 - 1.377 0.095 - 64.9 1 2 0 0.0008 19 0 0 0 6.94E+06 7.87E+06 - - - 0.3849 1 221125_WJC_METTL3_EV_vs_WT_F07.14407.14407.3 6.82E-08 13/88 K.EATAQK[136.11]PTGSVGSTVTTPPPLVR[166.11].G sp|Q86YP4|P66A_HUMAN 1 2311.2502 1.87 101466 14407 3 2311.255217 771.424 Transcriptional repressor p66-alpha OS=Homo sapiens OX=9606 GN=GATAD2A PE=1 SV=1 8.85 2545.7 - 202690 - - - 2.1512 - 2.621 0.65 - 110.8 1 2 0 0.005 23 0 0 0 3.12E+07 1.67E+07 - - - 8.0459 0.9986 221125_WJC_METTL3_EV_vs_WT_F07.14411.14411.4 1.92E-05 16/90 R.GTFHDDRDDGVDYWAK.R "tr|H0YF63|H0YF63_HUMAN,tr|E9PK91|E9PK91_HUMAN" 2 1895.8075 2.18 101468 14411 4 1895.815633 474.9591 Bcl-2-associated transcription factor 1 (Fragment) OS=Homo sapiens OX=9606 GN=BCLAF1 PE=1 SV=1 4.28 2546.3 - 7.81E+06 - - - 4.3137 - 2.438 0.484 - 193.9 1 2 1 0.0082 16 0 0 0 1.34E+09 6.15E+08 - - - 3.7504 0.9905 221125_WJC_METTL3_EV_vs_WT_F07.14412.14412.3 3.03E-10 16/64 Y.VHYEIDAC[160.03]MDSEAPGSK[136.11].D "sp|Q86U44|MTA70_HUMAN,tr|H0YFV6|H0YFV6_HUMAN" 2 1915.8172 0.02 101469 14412 3 1915.823677 639.613 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 4.31 2546.3 - 4.91E+06 - - - 3.3996 - 3.224 0.515 - 334.1 1 1 0 0.0065 17 0 0 0 5.09E+06 3.23E+08 - - - 7.2373 1 221125_WJC_METTL3_EV_vs_WT_F07.14413.14413.3 8.72E-08 16/60 R.EALLSSAVDHGSDEVK[136.11].F "sp|P78371|TCPB_HUMAN,tr|F8VQ14|F8VQ14_HUMAN,tr|F5GWF6|F5GWF6_HUMAN" 3 1663.8144 0.55 101470 14413 3 1663.819642 555.6121 T-complex protein 1 subunit beta OS=Homo sapiens OX=9606 GN=CCT2 PE=1 SV=4 4.31 2546.4 - 2.94E+06 - - - 3.1235 - 3.211 0.603 - 449.5 1 2 0 0.0052 16 0 0 0 1.63E+07 2.95E+07 - - - 8.2547 0.9803 221125_WJC_METTL3_EV_vs_WT_F07.14414.14414.3 0.00367 Nov-36 R.RKPFYPALIR.Y "sp|O00746|NDKM_HUMAN,tr|Q4TT34|Q4TT34_HUMAN,tr|H0Y6J0|H0Y6J0_HUMAN,tr|F2Z2X0|F2Z2X0_HUMAN,tr|A2IDC9|A2IDC9_HUMAN" 5 1259.7503 1.83 101471 14414 3 1259.753285 420.924 "Nucleoside diphosphate kinase, mitochondrial OS=Homo sapiens OX=9606 GN=NME4 PE=1 SV=1" 11 2546.5 - 1.52E+06 - - - 2.3997 - 1.899 0.138 - 169.1 1 2 0 0.003 10 0 0 0 6.48E+07 3.54E+07 - - - 1.9507 0.9999 221125_WJC_METTL3_EV_vs_WT_F07.14415.14415.3 7.26E-08 19/60 R.EALLSSAVDHGSDEVK.F "sp|P78371|TCPB_HUMAN,tr|F8VQ14|F8VQ14_HUMAN,tr|F5GWF6|F5GWF6_HUMAN" 3 1655.8002 0.42 101472 14415 3 1655.807235 552.9407 T-complex protein 1 subunit beta OS=Homo sapiens OX=9606 GN=CCT2 PE=1 SV=4 4.31 2546.5 - 1.31E+06 - - - 4.2215 - 3.839 0.579 - 645.6 1 2 0 0.007 16 0 0 0 1.67E+07 4.03E+07 - - - 8.445 0.988 221125_WJC_METTL3_EV_vs_WT_F07.14417.14417.3 0.000291 17/80 R.TQSSASLAASYAAQQHPQAAA.S sp|Q96PK6|RBM14_HUMAN 1 2057.9766 - 101474 14417 3 2057.984592 686.9995 RNA-binding protein 14 OS=Homo sapiens OX=9606 GN=RBM14 PE=1 SV=2 6.4 2546.8 - 535402 - - - 3.8611 - 3.777 0.509 - 327.8 1 1 0 0.0079 21 0 0 0 - - - - - 7.3987 0.9998 221125_WJC_METTL3_EV_vs_WT_F07.14419.14419.3 0.0136 13/68 R.SGGGFSSGSAGIINYQRR.T sp|P04264|K2C1_HUMAN 1 1812.8867 0.14 101476 14419 3 1812.88929 605.3028 "Keratin, type II cytoskeletal 1 OS=Homo sapiens OX=9606 GN=KRT1 PE=1 SV=6" 10.83 2547 - 392336 - - - 1.4237 - 2.395 0.37 - 167.1 1 2 0 0.0026 18 0 0 0 2.69E+06 1.95E+07 - - - 4.8392 1 221125_WJC_METTL3_EV_vs_WT_F07.14421.14421.3 5.79E-11 18/68 K.STLADYSAQKDLEPESDR.S "sp|Q9UKV3|ACINU_HUMAN,tr|S4R3H4|S4R3H4_HUMAN,tr|E7EQT4|E7EQT4_HUMAN" 3 2023.9334 1.24 101478 14421 3 2023.937815 675.6518 Apoptotic chromatin condensation inducer in the nucleus OS=Homo sapiens OX=9606 GN=ACIN1 PE=1 SV=2 4.1 2547.3 - 289156 - - - 2.1597 - 3.687 0.626 - 382.4 1 2 1 0.0044 18 0 0 0 2.98E+06 2.41E+06 - - - 8.7672 0.9976 221125_WJC_METTL3_EV_vs_WT_F07.14422.14422.4 0.000579 9/102 K.GK[136.11]PVGLVGVTELSDAQK[136.11]K[136.11].Q sp|Q8IWZ8|SUGP1_HUMAN 1 1849.0735 1.08 101479 14422 4 1849.080797 463.2757 SURP and G-patch domain-containing protein 1 OS=Homo sapiens OX=9606 GN=SUGP1 PE=1 SV=2 8.5 2547.4 - 175390 - - - 3.9393 - 1.844 0.35 - 48.1 1 2 0 0.0073 18 0 0 0 1.43E+06 1.32E+06 - - - 2.48 0.9999 221125_WJC_METTL3_EV_vs_WT_F07.14428.14428.3 7.95E-05 13/72 K.SVVSLKNEEENENSISQYK.E sp|P82673|RT35_HUMAN 1 2196.0546 0.91 101483 14428 3 2196.058578 733.0255 "28S ribosomal protein S35, mitochondrial OS=Homo sapiens OX=9606 GN=MRPS35 PE=1 SV=1" 4.49 2548 - 855419 - - - 1.8014 - 3.025 0.531 - 149 1 2 1 0.004 19 0 0 0 1.09E+07 1.20E+07 - - - 7.1785 0.9997 221125_WJC_METTL3_EV_vs_WT_F07.14429.14429.4 0.0012 15/78 R.LHISQLQHENSILK.G "sp|Q14203|DCTN1_HUMAN,tr|A0A804CDA6|A0A804CDA6_HUMAN,tr|E7EX90|E7EX90_HUMAN,tr|A0A7P0Z4C3|A0A7P0Z4C3_HUMAN,tr|E7EWF7|E7EWF7_HUMAN" 5 1658.9104 1.76 101484 14429 4 1658.91416 415.7349 Dynactin subunit 1 OS=Homo sapiens OX=9606 GN=DCTN1 PE=1 SV=3 6.92 2548.2 - 590791 - - - 2.2641 - 2.217 0.39 - 165.7 1 2 0 0.0038 14 0 0 0 9.28E+07 5.27E+07 - - - 2.9093 1 221125_WJC_METTL3_EV_vs_WT_F07.14430.14430.3 2.49E-09 16/60 R.TSIHEAMEQQSISISK.A "sp|P49736|MCM2_HUMAN,tr|H0Y8E6|H0Y8E6_HUMAN" 2 1787.8724 1.1 101485 14430 3 1787.87458 596.9647 DNA replication licensing factor MCM2 OS=Homo sapiens OX=9606 GN=MCM2 PE=1 SV=4 5.37 2548.3 - 538524 - - - 1.2395 - 2.851 0.57 - 462.1 1 2 0 0.0022 16 0 0 0 1.26E+07 1.14E+07 - - - 7.5825 0.9989 221125_WJC_METTL3_EV_vs_WT_F07.14432.14432.3 1.67E-05 Oct-68 R.AKGPGGTSDAYAVIQVGK.E sp|Q6WKZ4|RFIP1_HUMAN 1 1717.8999 1.04 101487 14432 3 1717.906043 573.6406 Rab11 family-interacting protein 1 OS=Homo sapiens OX=9606 GN=RAB11FIP1 PE=1 SV=3 8.54 2548.5 - 476288 - - - 3.5765 - 2.409 0.48 - 83.5 1 2 1 0.0061 18 0 0 0 1.90E+07 1.82E+07 - - - 6.0792 1 221125_WJC_METTL3_EV_vs_WT_F07.14435.14435.3 1.09E-07 15/76 R.QGAIVAVTGDGVNDSPALKK.A "sp|P05023|AT1A1_HUMAN,sp|P13637|AT1A3_HUMAN,sp|P50993|AT1A2_HUMAN,tr|A0A0A0MT26|A0A0A0MT26_HUMAN,tr|H0Y7C1|H0Y7C1_HUMAN,tr|A0A2R8YEY8|A0A2R8YEY8_HUMAN,tr|B1AKY9|B1AKY9_HUMAN,tr|M0R116|M0R116_HUMAN" 8 1939.0375 4.32 101490 14435 3 1939.039519 647.3531 Sodium\potassium-transporting ATPase subunit alpha-1 OS=Homo sapiens OX=9606 GN=ATP1A1 PE=1 SV=1 5.96 2548.9 - 277431 - - - 1.0644 - 2.96 0.561 - 259.9 1 2 0 0.0021 20 0 0 0 8.10E+06 1.87E+06 - - - 7.4267 1 221125_WJC_METTL3_EV_vs_WT_F07.14437.14437.2 1.11E-08 28-Sep K.YNDDSDDSYFTSSSR[166.11].P tr|H0Y6A0|H0Y6A0_HUMAN 1 1767.6735 -1 101492 14437 2 1767.673702 884.844 ADP-ribosylation factor GTPase-activating protein 3 (Fragment) OS=Homo sapiens OX=9606 GN=ARFGAP3 PE=1 SV=1 3.77 2549.1 - 77865.6 - - - 0.0933 - 2.303 0.79 - 180.7 1 1 0 0.0002 15 0 0 0 0.00E+00 0.00E+00 - - - 6.9268 0.9129 221125_WJC_METTL3_EV_vs_WT_F07.14444.14444.2 0.0813 20-Aug R.GTGFDGDQC[160.03]LG.V sp|O75717|WDHD1_HUMAN 1 1125.4397 - 101497 14444 2 1125.436933 563.7271 WD repeat and HMG-box DNA-binding protein 1 OS=Homo sapiens OX=9606 GN=WDHD1 PE=1 SV=1 3.56 2549.9 - 840911 - - - -2.4479 - 1.334 0.425 - 88.5 1 1 0 -0.0028 11 0 0 0 - - - - - 2.9588 1 221125_WJC_METTL3_EV_vs_WT_F07.14445.14445.2 1.26E-06 20/30 R.GTFHDDRDDGVDYWAK.R "tr|H0YF63|H0YF63_HUMAN,tr|E9PK91|E9PK91_HUMAN" 2 1895.8075 2.31 101498 14445 2 1895.810147 948.911 Bcl-2-associated transcription factor 1 (Fragment) OS=Homo sapiens OX=9606 GN=BCLAF1 PE=1 SV=1 4.28 2550.1 - 750212 - - - 1.42 - 3.237 0.7 - 1066.2 1 2 1 0.0027 16 0 0 0 3.16E+07 1.37E+07 - - - 7.0983 0.9808 221125_WJC_METTL3_EV_vs_WT_F07.14448.14448.4 0.0094 Oct-78 R.QHLASIYEK[136.11]EEDWR[166.11].N "sp|Q9BT78|CSN4_HUMAN,tr|D6RFN0|D6RFN0_HUMAN,tr|D6RAX7|D6RAX7_HUMAN" 3 1820.8812 0.72 101501 14448 4 1820.877153 456.2276 COP9 signalosome complex subunit 4 OS=Homo sapiens OX=9606 GN=COPS4 PE=1 SV=1 4.83 2550.4 - 239518 - - - -2.2407 - 1.723 0.254 - 65.7 1 2 1 -0.0041 14 0 0 0 2.62E+06 3.65E+06 - - - 1.6337 0.9999 221125_WJC_METTL3_EV_vs_WT_F07.14449.14449.3 0.015 Oct-36 K.K[136.11]SDVEAIFSK[136.11].Y "sp|P0DMR1|HNRC4_HUMAN,sp|P07910|HNRPC_HUMAN,sp|O60812|HNRC1_HUMAN,sp|B2RXH8|HNRC2_HUMAN,sp|B7ZW38|HNRC3_HUMAN,tr|G3V251|G3V251_HUMAN,tr|B4DY08|B4DY08_HUMAN,tr|G3V575|G3V575_HUMAN,tr|B4DSU6|B4DSU6_HUMAN,tr|G3V3K6|G3V3K6_HUMAN,tr|B2R5W2|B2R5W2_HUMAN,tr|G3V4C1|G3V4C1_HUMAN,tr|A0A0G2JPF8|A0A0G2JPF8_HUMAN,tr|A0A0G2JNQ3|A0A0G2JNQ3_HUMAN,tr|G3V576|G3V576_HUMAN,tr|G3V5X6|G3V5X6_HUMAN,tr|G3V2H6|G3V2H6_HUMAN,tr|G3V4W0|G3V4W0_HUMAN,tr|G3V555|G3V555_HUMAN,tr|G3V4M8|G3V4M8_HUMAN,tr|G3V2Q1|G3V2Q1_HUMAN" 21 1138.6205 0.001 101502 14449 3 1138.621511 380.5474 Heterogeneous nuclear ribonucleoprotein C-like 4 OS=Homo sapiens OX=9606 GN=HNRNPCL4 PE=3 SV=1 6.07 2550.6 - 156517 - - - 0.8967 - 2.119 0.407 - 170.3 1 2 0 0.001 10 0 0 0 0.00E+00 5.17E+06 - - - 5.2704 1 221125_WJC_METTL3_EV_vs_WT_F07.14453.14453.3 1.48E-08 15/52 R.LHISQLQHENSILK.G "sp|Q14203|DCTN1_HUMAN,tr|A0A804CDA6|A0A804CDA6_HUMAN,tr|E7EX90|E7EX90_HUMAN,tr|A0A7P0Z4C3|A0A7P0Z4C3_HUMAN,tr|E7EWF7|E7EWF7_HUMAN" 5 1658.9104 1.96 101504 14453 3 1658.911225 553.9774 Dynactin subunit 1 OS=Homo sapiens OX=9606 GN=DCTN1 PE=1 SV=3 6.92 2551.1 - 2.66E+06 - - - 0.4949 - 3.032 0.535 - 248.5 1 2 0 0.0008 14 0 0 0 1.32E+08 6.73E+07 - - - 7.4523 0.999 221125_WJC_METTL3_EV_vs_WT_F07.14455.14455.3 0.000674 Sep-48 R.ENDEEKVTFNLSK.G sp|O60870|KIN17_HUMAN 1 1551.7417 0.83 101506 14455 3 1551.739943 518.2545 DNA\RNA-binding protein KIN17 OS=Homo sapiens OX=9606 GN=KIN PE=1 SV=2 4.41 2551.3 - 730333 - - - -1.111 - 1.758 0.397 - 102.7 1 2 1 -0.0017 13 0 0 0 1.15E+07 1.38E+07 - - - 4.4953 1 221125_WJC_METTL3_EV_vs_WT_F07.14457.14457.2 3.60E-10 15/30 R.GTFHDDR[166.11]DDGVDYWAK[136.11].R "tr|H0YF63|H0YF63_HUMAN,tr|E9PK91|E9PK91_HUMAN" 2 1913.8299 2.31 101508 14457 2 1913.828894 957.9222 Bcl-2-associated transcription factor 1 (Fragment) OS=Homo sapiens OX=9606 GN=BCLAF1 PE=1 SV=1 4.28 2551.6 - 667504 - - - -0.5387 - 2.743 0.754 - 542.2 1 2 1 -0.001 16 0 0 0 3.16E+07 1.37E+07 - - - 7.0905 0.9976 221125_WJC_METTL3_EV_vs_WT_F07.14458.14458.3 0.0771 Nov-56 K.TKPYIQVDIGGGQTK.T "sp|P11021|BIP_HUMAN,tr|A0A7P0TB36|A0A7P0TB36_HUMAN,tr|A0A7P0TAI0|A0A7P0TAI0_HUMAN" 3 1603.857 0.54 101509 14458 3 1603.85767 535.6263 Endoplasmic reticulum chaperone BiP OS=Homo sapiens OX=9606 GN=HSPA5 PE=1 SV=2 8.17 2551.7 - 666880 - - - 0.4352 - 2.032 0.207 - 129.7 1 2 0 0.0007 15 0 0 0 1.34E+07 2.48E+07 - - - 2.6977 0.9935 221125_WJC_METTL3_EV_vs_WT_F07.14461.14461.3 0.00461 Aug-52 R.QHLASIYEKEEDWR.N "sp|Q9BT78|CSN4_HUMAN,tr|D6RFN0|D6RFN0_HUMAN,tr|D6RAX7|D6RAX7_HUMAN" 3 1802.8588 1.23 101512 14461 3 1802.857654 601.9602 COP9 signalosome complex subunit 4 OS=Homo sapiens OX=9606 GN=COPS4 PE=1 SV=1 4.83 2552.1 - 159345 - - - -0.6151 - 1.463 0.315 - 81.7 1 2 1 -0.0011 14 0 0 0 2.42E+06 1.96E+06 - - - 3.0628 0.9999 221125_WJC_METTL3_EV_vs_WT_F07.14464.14464.2 0.000377 20-Dec K.LSAMMGAVAEK[136.11].K "sp|Q86U44|MTA70_HUMAN,tr|F5H6D8|F5H6D8_HUMAN,tr|H0YFV6|H0YFV6_HUMAN,tr|B4DTN4|B4DTN4_HUMAN" 4 1114.5606 0.03 101513 14464 2 1114.560953 558.2876 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 6 2552.5 - 2.98E+06 - - - 0.3149 - 2.234 0.511 - 446.7 1 2 0 0.0004 11 0 0 0 5.18E+06 1.86E+08 - - - 4.9896 0.9998 221125_WJC_METTL3_EV_vs_WT_F07.14467.14467.3 7.94E-06 14/56 K.KAEAGAGSATEFQFR.G "sp|Q9NQ39|RS10L_HUMAN,sp|P46783|RS10_HUMAN" 2 1568.7583 1.95 101516 14467 3 1568.763088 523.9267 Putative 40S ribosomal protein S10-like OS=Homo sapiens OX=9606 GN=RPS10P5 PE=5 SV=1 6.14 2552.8 - 663967 - - - 3.0393 - 2.563 0.424 - 280 1 2 0 0.0048 15 0 0 0 1.73E+07 8.84E+06 - - - 5.7217 0.9991 221125_WJC_METTL3_EV_vs_WT_F07.14473.14473.3 4.68E-05 Dec-68 R.AK[136.11]GPGGTSDAYAVIQVGK[136.11].E sp|Q6WKZ4|RFIP1_HUMAN 1 1733.9283 1.05 101520 14473 3 1733.933567 578.9834 Rab11 family-interacting protein 1 OS=Homo sapiens OX=9606 GN=RAB11FIP1 PE=1 SV=3 8.54 2553.6 - 793825 - - - 3.0382 - 2.362 0.47 - 121.9 1 2 1 0.0053 18 0 0 0 2.08E+07 1.99E+07 - - - 5.9188 0.9999 221125_WJC_METTL3_EV_vs_WT_F07.14479.14479.3 0.00142 Oct-40 K.HIYFINC[160.03]GDSR.A "sp|O75688|PPM1B_HUMAN,tr|B8ZZF0|B8ZZF0_HUMAN,tr|A0A3B3IS24|A0A3B3IS24_HUMAN,tr|C9JIR6|C9JIR6_HUMAN" 4 1380.6245 2.99 101524 14479 3 1380.627095 461.2154 Protein phosphatase 1B OS=Homo sapiens OX=9606 GN=PPM1B PE=1 SV=1 6.73 2554.4 - 427817 - - - 1.902 - 2.001 0.515 - 213.1 1 2 0 0.0026 11 0 0 0 2.38E+07 7.98E+06 - - - 6.2515 0.9985 221125_WJC_METTL3_EV_vs_WT_F07.14484.14484.3 0.00171 Dec-44 R.DTPITHISFHPK.R "sp|Q969X6|UTP4_HUMAN,tr|H3BSH7|H3BSH7_HUMAN,tr|A0A0J9YWK2|A0A0J9YWK2_HUMAN,tr|A0A0J9YXV4|A0A0J9YXV4_HUMAN,tr|A0A0J9YWM9|A0A0J9YWM9_HUMAN" 5 1391.7197 24.47 101529 14484 3 1391.719673 464.9139 U3 small nucleolar RNA-associated protein 4 homolog OS=Homo sapiens OX=9606 GN=UTP4 PE=1 SV=1 6.92 2555 - 631589 - - - -0.0553 - 2.353 0.189 - 169.7 1 2 0 -0.0001 12 0 0 0 2.65E+07 1.08E+06 - - - 3.019 0.9913 221125_WJC_METTL3_EV_vs_WT_F07.14490.14490.3 0.0035 14/44 S.HK[136.11]PDEIYGMIER[166.11].L sp|Q86U44|MTA70_HUMAN 1 1504.7463 0.001 101533 14490 3 1504.743766 502.5894 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 5.45 2555.7 - 1.16E+06 - - - -1.6966 - 2.54 0.417 - 247.9 1 1 0 -0.0026 12 0 0 0 0.00E+00 8.04E+07 - - - 5.7723 0.9998 221125_WJC_METTL3_EV_vs_WT_F07.14491.14491.3 7.11E-09 15/64 K.DPQALSEHLKNPVIAQK.L sp|P31948|STIP1_HUMAN 1 1887.0214 1.43 101534 14491 3 1887.026002 630.0144 Stress-induced-phosphoprotein 1 OS=Homo sapiens OX=9606 GN=STIP1 PE=1 SV=1 6.75 2555.9 - 977425 - - - 2.4329 - 3.184 0.552 - 366.1 1 2 1 0.0046 17 0 0 0 1.99E+07 1.40E+07 - - - 7.6188 0.9998 221125_WJC_METTL3_EV_vs_WT_F07.14492.14492.3 2.32E-05 14/64 K.DPQALSEHLK[136.11]NPVIAQK[136.11].L sp|P31948|STIP1_HUMAN 1 1903.0498 1.43 101535 14492 3 1903.04902 635.3572 Stress-induced-phosphoprotein 1 OS=Homo sapiens OX=9606 GN=STIP1 PE=1 SV=1 6.75 2556 - 861956 - - - -0.4156 - 2.304 0.473 - 165.6 1 2 1 -0.0008 17 0 0 0 1.99E+07 1.40E+07 - - - 5.9218 0.9952 221125_WJC_METTL3_EV_vs_WT_F07.14495.14495.3 6.46E-06 14/56 F.WGQK[136.11]PWSQHYHQGYY.- "sp|Q00839|HNRPU_HUMAN,tr|A0A1W2PPL4|A0A1W2PPL4_HUMAN,tr|A0A087WVI9|A0A087WVI9_HUMAN,tr|Q5RI18|Q5RI18_HUMAN,tr|A0A1W2PP35|A0A1W2PP35_HUMAN,tr|A0A1W2PPH7|A0A1W2PPH7_HUMAN,tr|A0A1W2PQD4|A0A1W2PQD4_HUMAN,tr|A0A1X7SBS1|A0A1X7SBS1_HUMAN" 8 1971.8896 0.9 101536 14495 3 1971.888683 658.3038 Heterogeneous nuclear ribonucleoprotein U OS=Homo sapiens OX=9606 GN=HNRNPU PE=1 SV=6 8.45 2556.4 - 1.05E+06 - - - -0.4732 - 2.83 0.426 - 164.2 1 1 0 -0.0009 15 0 0 0 2.22E+07 2.47E+07 - - - 6.0037 0.9998 221125_WJC_METTL3_EV_vs_WT_F07.14498.14498.3 0.00793 16/60 K.VQQLQISVDQHGDNLK.N sp|P19013|K2C4_HUMAN 1 1820.9381 280.94 101539 14498 3 1820.940937 607.9866 "Keratin, type II cytoskeletal 4 OS=Homo sapiens OX=9606 GN=KRT4 PE=1 SV=5" 5.21 2556.6 - 1.76E+06 - - - 1.5717 - 2.341 0.361 - 342 1 2 0 0.0029 16 0 0 0 3.29E+07 1.17E+05 - - - 4.7465 1 221125_WJC_METTL3_EV_vs_WT_F07.14499.14499.3 0.000232 15/80 R.TYFSC[160.03]TSAHTSTGDGTAMITR[166.11].A "sp|P31040|SDHA_HUMAN,tr|D6RFM5|D6RFM5_HUMAN,tr|A0A494C1T6|A0A494C1T6_HUMAN" 3 2273.9921 0.7 101540 14499 3 2273.991943 759.0046 "Succinate dehydrogenase [ubiquinone] flavoprotein subunit, mitochondrial OS=Homo sapiens OX=9606 GN=SDHA PE=1 SV=2" 6.4 2556.7 - 433006 - - - -0.0479 - 3.271 0.685 - 120.9 1 2 0 -0.0001 21 0 0 0 1.85E+07 2.63E+07 - - - 9.0183 0.991 221125_WJC_METTL3_EV_vs_WT_F07.14502.14502.3 0.00377 13/56 F.WGQKPWSQHYHQGYY.- "sp|Q00839|HNRPU_HUMAN,tr|A0A1W2PPL4|A0A1W2PPL4_HUMAN,tr|A0A087WVI9|A0A087WVI9_HUMAN,tr|Q5RI18|Q5RI18_HUMAN,tr|A0A1W2PP35|A0A1W2PP35_HUMAN,tr|A0A1W2PPH7|A0A1W2PPH7_HUMAN,tr|A0A1W2PQD4|A0A1W2PQD4_HUMAN,tr|A0A1X7SBS1|A0A1X7SBS1_HUMAN" 8 1963.8754 0.9 101541 14502 3 1963.875077 655.6324 Heterogeneous nuclear ribonucleoprotein U OS=Homo sapiens OX=9606 GN=HNRNPU PE=1 SV=6 8.45 2557.1 - 1.16E+06 - - - -0.1726 - 2.197 0.425 - 97.4 1 1 0 -0.0003 15 0 0 0 2.22E+07 2.46E+07 - - - 5.332 0.8136 221125_WJC_METTL3_EV_vs_WT_F07.14510.14510.2 5.58 26-Apr R.LHISQLQHENSILK.G "sp|Q14203|DCTN1_HUMAN,tr|A0A804CDA6|A0A804CDA6_HUMAN,tr|E7EX90|E7EX90_HUMAN,tr|A0A7P0Z4C3|A0A7P0Z4C3_HUMAN,tr|E7EWF7|E7EWF7_HUMAN" 5 1658.9104 5.56 101549 14510 2 1658.914533 830.4625 Dynactin subunit 1 OS=Homo sapiens OX=9606 GN=DCTN1 PE=1 SV=3 6.92 2558.1 - 168173 - - - 2.489 - 1.057 0.063 - 41.8 4 2 0 0.0041 14 0 0 0 2.40E+06 4.32E+05 - - - -0.6248 0.9996 221125_WJC_METTL3_EV_vs_WT_F07.14511.14511.3 0.002 Sep-48 R.SIFQHIQSAQSQR[166.11].S "sp|Q9Y2W1|TR150_HUMAN,tr|A0A3B3ITZ9|A0A3B3ITZ9_HUMAN" 2 1538.7829 2.48 101550 14511 3 1538.782183 513.9349 Thyroid hormone receptor-associated protein 3 OS=Homo sapiens OX=9606 GN=THRAP3 PE=1 SV=2 9.49 2558.2 - 142789 - - - -0.4718 - 1.852 0.343 - 61.5 1 2 0 -0.0007 13 0 0 0 1.74E+07 7.00E+06 - - - 4.0348 0.8827 221125_WJC_METTL3_EV_vs_WT_F07.14514.14514.3 1.05E-05 14/48 T.SHK[136.11]PDEIYGMIER[166.11].L sp|Q86U44|MTA70_HUMAN 1 1591.7783 0.02 101551 14514 3 1591.786807 531.6001 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 5.42 2558.6 - 1.13E+06 - - - 5.3148 - 2.223 0.447 - 300.4 1 1 0 0.0085 13 0 0 0 6.14E+06 3.32E+08 - - - 5.6872 1 221125_WJC_METTL3_EV_vs_WT_F07.14516.14516.4 5.08E-10 21/96 R.AFDQDGDGHITVDELRR.A sp|Q9NZT1|CALL5_HUMAN 1 1942.9133 14.17 101553 14516 4 1942.914138 486.7356 Calmodulin-like protein 5 OS=Homo sapiens OX=9606 GN=CALML5 PE=1 SV=2 4.35 2558.8 - 2.91E+06 - - - 0.4226 - 3.301 0.633 - 373.1 1 2 0 0.0008 17 0 0 0 4.68E+07 3.30E+06 - - - 5.15 0.9999 221125_WJC_METTL3_EV_vs_WT_F07.14518.14518.3 4.05E-05 Nov-44 R.TFIAIKPDGVQR.G "sp|P15531|NDKA_HUMAN,sp|P22392|NDKB_HUMAN,tr|Q32Q12|Q32Q12_HUMAN,tr|Q32Q12|Q32Q12_HUMAN,tr|J3KPD9|J3KPD9_HUMAN,tr|F6XY72|F6XY72_HUMAN,tr|E5RHP0|E5RHP0_HUMAN,tr|E7ERL0|E7ERL0_HUMAN,tr|C9K028|C9K028_HUMAN" 9 1343.7561 1.39 101555 14518 3 1343.75607 448.926 Nucleoside diphosphate kinase A OS=Homo sapiens OX=9606 GN=NME1 PE=1 SV=1 8.41 2559 - 604106 - - - -0.0484 - 2.115 0.454 - 134.7 1 2 0 -0.0001 12 0 0 0 1.48E+07 1.06E+07 - - - 5.6779 0.9999 221125_WJC_METTL3_EV_vs_WT_F07.14519.14519.3 9.01E-07 14/72 R.C[160.03]SVC[160.03]SEPIMPEPGR[166.11]DETVR[166.11].V "sp|Q15942|ZYX_HUMAN,tr|H0Y2Y8|H0Y2Y8_HUMAN" 2 2237.9982 4.43 101556 14519 3 2237.998252 747.0067 Zyxin OS=Homo sapiens OX=9606 GN=ZYX PE=1 SV=1 4.41 2559.2 - 410932 - - - 0.017 - 2.578 0.591 - 193.7 1 2 1 0 19 0 0 0 1.32E+08 2.97E+07 - - - 7.4557 1 221125_WJC_METTL3_EV_vs_WT_F07.14521.14521.3 7.53E-08 18/60 R.GTFHDDRDDGVDYWAK.R "tr|H0YF63|H0YF63_HUMAN,tr|E9PK91|E9PK91_HUMAN" 2 1895.8075 1.99 101557 14521 3 1895.809974 632.9431 Bcl-2-associated transcription factor 1 (Fragment) OS=Homo sapiens OX=9606 GN=BCLAF1 PE=1 SV=1 4.28 2559.4 - 1.42E+07 - - - 1.3287 - 3.069 0.674 - 306.1 1 2 1 0.0025 16 0 0 0 1.09E+09 5.49E+08 - - - 8.931 0.9999 221125_WJC_METTL3_EV_vs_WT_F07.14523.14523.4 0.00196 13/78 R.LHISQLQHENSILK[136.11].G "sp|Q14203|DCTN1_HUMAN,tr|A0A804CDA6|A0A804CDA6_HUMAN,tr|E7EX90|E7EX90_HUMAN,tr|A0A7P0Z4C3|A0A7P0Z4C3_HUMAN,tr|E7EWF7|E7EWF7_HUMAN" 5 1666.9246 1.77 101558 14523 4 1666.924848 417.7384 Dynactin subunit 1 OS=Homo sapiens OX=9606 GN=DCTN1 PE=1 SV=3 6.92 2559.6 - 1.64E+06 - - - 0.1464 - 2.677 0.422 - 123.1 1 2 0 0.0002 14 0 0 0 9.29E+07 5.26E+07 - - - 3.2574 1 221125_WJC_METTL3_EV_vs_WT_F07.14525.14525.3 2.37E-07 14/64 R.AFDQDGDGHITVDELRR.A sp|Q9NZT1|CALL5_HUMAN 1 1942.9133 9.71 101560 14525 3 1942.914509 648.645 Calmodulin-like protein 5 OS=Homo sapiens OX=9606 GN=CALML5 PE=1 SV=2 4.35 2559.8 - 996267 - - - 0.6135 - 2.5 0.529 - 207.9 1 2 0 0.0012 17 0 0 0 1.67E+07 1.72E+06 - - - 6.7523 1 221125_WJC_METTL3_EV_vs_WT_F07.14526.14526.3 1.87E-13 19/80 R.TYFSC[160.03]TSAHTSTGDGTAMITR.A "sp|P31040|SDHA_HUMAN,tr|D6RFM5|D6RFM5_HUMAN,tr|A0A494C1T6|A0A494C1T6_HUMAN" 3 2263.9838 0.7 101561 14526 3 2263.986949 755.6685 "Succinate dehydrogenase [ubiquinone] flavoprotein subunit, mitochondrial OS=Homo sapiens OX=9606 GN=SDHA PE=1 SV=2" 6.4 2559.9 - 576433 - - - 1.3989 - 3.511 0.703 - 235.7 1 2 0 0.0032 21 0 0 0 1.85E+07 2.63E+07 - - - 9.3878 0.9971 221125_WJC_METTL3_EV_vs_WT_F07.14527.14527.4 0.00675 Nov-78 K.VFIQHITLSDEER[166.11]K[136.11].L "sp|Q14527|HLTF_HUMAN,tr|H7C5K0|H7C5K0_HUMAN,tr|A0A0C4DGA6|A0A0C4DGA6_HUMAN" 3 1731.9275 1.23 101562 14527 4 1731.926003 433.9891 Helicase-like transcription factor OS=Homo sapiens OX=9606 GN=HLTF PE=1 SV=2 5.44 2560.1 - 471552 - - - -0.8378 - 1.928 0.275 - 55.8 2 2 0 -0.0015 14 0 0 0 1.65E+07 1.35E+07 - - - 1.6287 0.9917 221125_WJC_METTL3_EV_vs_WT_F07.14528.14528.3 4.95E-06 14/36 L.VNHFVEEFK[136.11]R[166.11].K "sp|P0DMV8|HS71A_HUMAN,sp|P0DMV9|HS71B_HUMAN,tr|V9GZ37|V9GZ37_HUMAN,tr|A0A0G2JIW1|A0A0G2JIW1_HUMAN" 4 1321.6898 0.11 101563 14528 3 1321.69121 441.5705 Heat shock 70 kDa protein 1A OS=Homo sapiens OX=9606 GN=HSPA1A PE=1 SV=1 6.73 2560.2 - 459308 - - - 1.0744 - 2.825 0.357 - 436.6 1 1 0 0.0014 10 0 0 0 1.99E+06 1.84E+07 - - - 5.5527 0.9999 221125_WJC_METTL3_EV_vs_WT_F07.14530.14530.2 5.39E-07 Jul-34 R.SQANGAGALSYVSPNTSK[136.11].C "sp|O95453|PARN_HUMAN,tr|A0A494C0Q6|A0A494C0Q6_HUMAN,tr|A0A494BZW7|A0A494BZW7_HUMAN,tr|A0A494C0Q2|A0A494C0Q2_HUMAN,tr|A0A494BZU6|A0A494BZU6_HUMAN,tr|A0A494C1G3|A0A494C1G3_HUMAN,tr|A0A494C002|A0A494C002_HUMAN,tr|A0A494C1K5|A0A494C1K5_HUMAN,tr|A0A494C156|A0A494C156_HUMAN,tr|F5H1Z4|F5H1Z4_HUMAN,tr|A0A494C1N1|A0A494C1N1_HUMAN,tr|A0A494C0W0|A0A494C0W0_HUMAN,tr|A0A494C0P9|A0A494C0P9_HUMAN,tr|A0A494C0K5|A0A494C0K5_HUMAN" 14 1758.8628 0.95 101565 14530 2 1758.861597 880.4387 Poly(A)-specific ribonuclease PARN OS=Homo sapiens OX=9606 GN=PARN PE=1 SV=1 8.31 2560.5 - 184996 - - - -0.6794 - 1.956 0.574 - 113.2 1 2 0 -0.0012 18 0 0 0 7.47E+06 7.87E+06 - - - 4.9296 1 221125_WJC_METTL3_EV_vs_WT_F07.14535.14535.3 3.52E-11 19/48 K.HVMSNTGNWMHIR.Y sp|Q8NFH5|NUP35_HUMAN 1 1581.7293 52.42 101568 14535 3 1581.729406 528.2504 Nucleoporin NUP35 OS=Homo sapiens OX=9606 GN=NUP35 PE=1 SV=1 9.76 2561.1 - 867696 - - - 0.0765 - 3.511 0.65 - 523.1 1 2 0 0.0001 13 0 0 0 1.59E+07 3.03E+05 - - - 9.1919 0.9784 221125_WJC_METTL3_EV_vs_WT_F07.14537.14537.4 1.48E-05 15/72 T.SHK[136.11]PDEIYGMIER[166.11].L sp|Q86U44|MTA70_HUMAN 1 1591.7783 0 101570 14537 4 1591.77528 398.9519 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 5.42 2561.3 - 740336 - - - -1.9268 - 2.525 0.398 - 180.1 1 1 0 -0.0031 13 0 0 0 2.37E+05 6.04E+07 - - - 3.0328 0.9999 221125_WJC_METTL3_EV_vs_WT_F07.14538.14538.4 3.10E-05 17/84 R.STSHK[136.11]PDEIYGMIER[166.11].L sp|Q86U44|MTA70_HUMAN 1 1779.8581 0.1 101571 14538 4 1779.858691 445.9718 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 5.42 2561.5 - 704564 - - - 0.3579 - 2.572 0.462 - 185.6 1 2 0 0.0006 15 0 0 0 1.66E+07 1.61E+08 - - - 3.5851 0.9999 221125_WJC_METTL3_EV_vs_WT_F07.14539.14539.3 0.000269 Oct-44 R.TFIAIK[136.11]PDGVQR[166.11].G "sp|P15531|NDKA_HUMAN,sp|P22392|NDKB_HUMAN,tr|Q32Q12|Q32Q12_HUMAN,tr|Q32Q12|Q32Q12_HUMAN,tr|J3KPD9|J3KPD9_HUMAN,tr|F6XY72|F6XY72_HUMAN,tr|E5RHP0|E5RHP0_HUMAN,tr|E7ERL0|E7ERL0_HUMAN,tr|C9K028|C9K028_HUMAN" 9 1361.7786 1.41 101572 14539 3 1361.779712 454.9335 Nucleoside diphosphate kinase A OS=Homo sapiens OX=9606 GN=NME1 PE=1 SV=1 8.41 2561.6 - 603086 - - - 0.8129 - 1.917 0.441 - 106.8 1 2 0 0.0011 12 0 0 0 1.45E+07 1.03E+07 - - - 5.2602 1 221125_WJC_METTL3_EV_vs_WT_F07.14542.14542.2 8.75E-09 Oct-34 R.SQANGAGALSYVSPNTSK.C "sp|O95453|PARN_HUMAN,tr|A0A494C0Q6|A0A494C0Q6_HUMAN,tr|A0A494BZW7|A0A494BZW7_HUMAN,tr|A0A494C0Q2|A0A494C0Q2_HUMAN,tr|A0A494BZU6|A0A494BZU6_HUMAN,tr|A0A494C1G3|A0A494C1G3_HUMAN,tr|A0A494C002|A0A494C002_HUMAN,tr|A0A494C1K5|A0A494C1K5_HUMAN,tr|A0A494C156|A0A494C156_HUMAN,tr|F5H1Z4|F5H1Z4_HUMAN,tr|A0A494C1N1|A0A494C1N1_HUMAN,tr|A0A494C0W0|A0A494C0W0_HUMAN,tr|A0A494C0P9|A0A494C0P9_HUMAN,tr|A0A494C0K5|A0A494C0K5_HUMAN" 14 1750.8486 0.95 101575 14542 2 1750.849594 876.4316 Poly(A)-specific ribonuclease PARN OS=Homo sapiens OX=9606 GN=PARN PE=1 SV=1 8.31 2562 - 155410 - - - 0.5723 - 2.494 0.657 - 225.5 1 2 0 0.001 18 0 0 0 7.47E+06 7.87E+06 - - - 6.1401 0.9993 221125_WJC_METTL3_EV_vs_WT_F07.14549.14549.4 0.016 14/78 K.VFIQHITLSDEERK.L "sp|Q14527|HLTF_HUMAN,tr|H7C5K0|H7C5K0_HUMAN,tr|A0A0C4DGA6|A0A0C4DGA6_HUMAN" 3 1713.905 1.22 101580 14549 4 1713.905432 429.4835 Helicase-like transcription factor OS=Homo sapiens OX=9606 GN=HLTF PE=1 SV=2 5.44 2562.8 - 631733 - - - 0.2614 - 2.217 0.307 - 101.1 1 2 0 0.0004 14 0 0 0 1.64E+07 1.34E+07 - - - 2.1878 0.9749 221125_WJC_METTL3_EV_vs_WT_F07.14554.14554.4 0.138 14/78 K.LQEELDK[136.11]YSQALR[166.11]K[136.11].N "sp|Q15643|TRIPB_HUMAN,tr|H0YJ97|H0YJ97_HUMAN" 2 1745.9522 0.99 101583 14554 4 1745.950037 437.4953 Thyroid receptor-interacting protein 11 OS=Homo sapiens OX=9606 GN=TRIP11 PE=1 SV=3 6.18 2563.5 - 880957 - - - -1.2497 - 2.439 0.204 - 182 1 2 1 -0.0022 14 0 0 0 1.70E+07 1.72E+07 - - - 1.3255 1 221125_WJC_METTL3_EV_vs_WT_F07.14561.14561.3 5.66E-07 22/64 K.QRDETALQLSVSQEQVK.Q "sp|Q15643|TRIPB_HUMAN,tr|H0YJI2|H0YJI2_HUMAN,tr|H0YJ97|H0YJ97_HUMAN" 3 1958.0069 1.17 101588 14561 3 1958.006816 653.6762 Thyroid receptor-interacting protein 11 OS=Homo sapiens OX=9606 GN=TRIP11 PE=1 SV=3 4.68 2564.3 - 2.93E+06 - - - -0.0342 - 4.312 0.567 - 691.7 1 2 1 -0.0001 17 0 0 0 1.79E+08 1.53E+08 - - - 8.5534 0.9997 221125_WJC_METTL3_EV_vs_WT_F07.14563.14563.4 5.93E-06 19/96 K.NLLNANLSEDEKEQLKK.L "sp|Q9UPS8|ANR26_HUMAN,tr|A0A6Q8PG48|A0A6Q8PG48_HUMAN,tr|E7ESJ3|E7ESJ3_HUMAN" 3 1985.0429 5.03 101590 14563 4 1985.04319 497.268 Ankyrin repeat domain-containing protein 26 OS=Homo sapiens OX=9606 GN=ANKRD26 PE=1 SV=4 4.87 2564.6 - 737118 - - - 0.1285 - 3.16 0.44 - 258.7 1 2 1 0.0003 17 0 0 0 1.36E+07 2.69E+06 - - - 3.4552 0.9999 221125_WJC_METTL3_EV_vs_WT_F07.14568.14568.2 6.08E-08 22-Dec R.FLEQQNQVLQTK.W "sp|Q7Z794|K2C1B_HUMAN,sp|P04264|K2C1_HUMAN,sp|P35908|K22E_HUMAN" 3 1474.778 999 101593 14568 2 1474.776983 738.3963 "Keratin, type II cytoskeletal 1b OS=Homo sapiens OX=9606 GN=KRT77 PE=1 SV=3" 6 2565.1 - 3.08E+06 - - - -0.6848 - 2.606 0.55 - 478.9 1 2 0 -0.001 12 0 0 0 8.57E+07 0.00E+00 - - - 5.6232 0.9978 221125_WJC_METTL3_EV_vs_WT_F07.14569.14569.4 0.000248 16/78 K.LQEELDKYSQALRK.N "sp|Q15643|TRIPB_HUMAN,tr|H0YJ97|H0YJ97_HUMAN" 2 1719.9155 0.99 101594 14569 4 1719.914526 430.9862 Thyroid receptor-interacting protein 11 OS=Homo sapiens OX=9606 GN=TRIP11 PE=1 SV=3 6.18 2565.3 - 1.09E+06 - - - -0.5948 - 2.501 0.316 - 249.2 1 2 1 -0.001 14 0 0 0 1.70E+07 1.72E+07 - - - 2.3098 0.9715 221125_WJC_METTL3_EV_vs_WT_F07.14573.14573.3 0.536 Oct-64 K.SSTKPAAGGTAPLPPWK.S "sp|Q15942|ZYX_HUMAN,tr|H7C3D3|H7C3D3_HUMAN,tr|H0Y2Y8|H0Y2Y8_HUMAN,tr|H7C3R3|H7C3R3_HUMAN" 4 1664.8886 4.98 101596 14573 3 1664.886282 555.9701 Zyxin OS=Homo sapiens OX=9606 GN=ZYX PE=1 SV=1 10 2565.8 - 525850 - - - -1.3959 - 1.779 0.117 - 68.4 1 2 0 -0.0023 17 0 0 0 1.67E+07 3.37E+06 - - - 1.2991 0.9999 221125_WJC_METTL3_EV_vs_WT_F07.14574.14574.2 1.39E-07 14/20 R.LVNHFVEEFK[136.11]R[166.11].K "sp|P0DMV8|HS71A_HUMAN,sp|P0DMV9|HS71B_HUMAN,tr|V9GZ37|V9GZ37_HUMAN,tr|A0A0G2JIW1|A0A0G2JIW1_HUMAN" 4 1434.7739 0.02 101597 14574 2 1434.77565 718.3942 Heat shock 70 kDa protein 1A OS=Homo sapiens OX=9606 GN=HSPA1A PE=1 SV=1 6.76 2565.9 - 524928 - - - 1.2518 - 2.39 0.548 - 711 1 2 0 0.0018 11 0 0 0 3.71E+05 1.98E+07 - - - 5.445 0.9866 221125_WJC_METTL3_EV_vs_WT_F07.14577.14577.2 1.85E-05 24-Oct T.SHK[136.11]PDEIYGMIER[166.11].L sp|Q86U44|MTA70_HUMAN 1 1591.7783 0.001 101600 14577 2 1591.780753 796.8964 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 5.42 2566.3 - 444149 - - - 1.5115 - 1.891 0.548 - 218.1 1 1 0 0.0024 13 0 0 0 0.00E+00 1.14E+07 - - - 4.7229 0.9943 221125_WJC_METTL3_EV_vs_WT_F07.14578.14578.3 3.82E-06 Nov-68 S.FSNTPNSGYTQSQFSAPR.D "sp|Q14444|CAPR1_HUMAN,tr|G3V153|G3V153_HUMAN" 2 1987.9024 0.92 101601 14578 3 1987.90374 663.6414 Caprin-1 OS=Homo sapiens OX=9606 GN=CAPRIN1 PE=1 SV=2 8.75 2566.4 - 371136 - - - 0.665 - 2.298 0.466 - 164.8 1 1 0 0.0013 18 0 0 0 5.85E+06 6.33E+06 - - - 5.8069 0.9999 221125_WJC_METTL3_EV_vs_WT_F07.14581.14581.2 1.84E-05 28-Sep R.STSHK[136.11]PDEIYGMIER[166.11].L sp|Q86U44|MTA70_HUMAN 1 1779.8581 0.001 101602 14581 2 1779.857392 890.9363 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 5.42 2566.8 - 336803 - - - -0.3719 - 2.02 0.513 - 158.7 1 2 0 -0.0007 15 0 0 0 0.00E+00 8.63E+06 - - - 4.5584 1 221125_WJC_METTL3_EV_vs_WT_F07.14584.14584.3 1.83E-05 23/60 K.SQLPDLSGPHSYSPGR.N "sp|Q86XL3|ANKL2_HUMAN,tr|F5H1D4|F5H1D4_HUMAN" 2 1696.8169 1.44 101605 14584 3 1696.820786 566.6129 Ankyrin repeat and LEM domain-containing protein 2 OS=Homo sapiens OX=9606 GN=ANKLE2 PE=1 SV=4 6.46 2567.2 - 483786 - - - 2.2913 - 3.292 0.531 - 696.6 1 2 0 0.0039 16 0 0 0 3.15E+07 2.18E+07 - - - 7.5163 0.9619 221125_WJC_METTL3_EV_vs_WT_F07.14585.14585.4 0.0359 Aug-96 R.VHLPTQPAADTYSEFHK[136.11].H "sp|Q6W2J9|BCOR_HUMAN,tr|H7BZ37|H7BZ37_HUMAN,tr|H7C2V9|H7C2V9_HUMAN,tr|H7BYY2|H7BYY2_HUMAN,tr|H7C231|H7C231_HUMAN" 5 1947.957 1.69 101606 14585 4 1947.960352 487.9965 BCL-6 corepressor OS=Homo sapiens OX=9606 GN=BCOR PE=1 SV=1 5.99 2567.4 - 279513 - - - 1.7069 - 1.702 0.186 - 43.9 2 2 0 0.0033 17 0 0 0 1.30E+08 7.69E+07 - - - 0.7992 0.7854 221125_WJC_METTL3_EV_vs_WT_F07.14589.14589.3 3.00E-05 14/64 R.AQVQEFC[160.03]DYGTK[136.11]EEC[160.03]MK[136.11].A "sp|Q86U44|MTA70_HUMAN,tr|H0YFV6|H0YFV6_HUMAN" 2 2137.909 0.06 101608 14589 3 2138.893986 713.6436 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 4.41 2567.8 - 809297 - - - 460.7413 - 2.482 0.615 - 146.9 1 2 1 0.985 17 0 0 0 1.97E+06 3.46E+07 - - - 7.4204 1 221125_WJC_METTL3_EV_vs_WT_F07.14595.14595.3 2.60E-11 29/76 K.AATGEEVSAEDLGGADLHC[160.03]R[166.11].K "sp|Q9HCC0|MCCB_HUMAN,tr|A0A804HJW5|A0A804HJW5_HUMAN,tr|A0A804HJC1|A0A804HJC1_HUMAN,tr|A0A804HK37|A0A804HK37_HUMAN,tr|A0A804HIH3|A0A804HIH3_HUMAN,tr|A0A804HJ24|A0A804HJ24_HUMAN,tr|A0A804HL02|A0A804HL02_HUMAN,tr|D6RD67|D6RD67_HUMAN,tr|A0A804HKE8|A0A804HKE8_HUMAN,tr|D6RDF7|D6RDF7_HUMAN,tr|A0A804HJ84|A0A804HJ84_HUMAN,tr|A0A804HJW2|A0A804HJW2_HUMAN,tr|A0A804HLJ9|A0A804HLJ9_HUMAN,tr|D6R9R1|D6R9R1_HUMAN,tr|A0A804HHS4|A0A804HHS4_HUMAN,tr|A0A804HJL2|A0A804HJL2_HUMAN,tr|A0A0S2Z5R4|A0A0S2Z5R4_HUMAN,tr|A0A804HJ31|A0A804HJ31_HUMAN" 18 2066.9203 1.13 101612 14595 3 2066.917686 689.9807 "Methylcrotonoyl-CoA carboxylase beta chain, mitochondrial OS=Homo sapiens OX=9606 GN=MCCC2 PE=1 SV=1" 4.17 2568.6 - 1.66E+06 - - - -1.2487 - 4.954 0.675 - 1107 1 2 0 -0.0026 20 0 0 0 3.74E+07 3.29E+07 - - - 9.947 0.9164 221125_WJC_METTL3_EV_vs_WT_F07.14598.14598.3 0.167 Jul-44 R.FLEQQNQVLQTK.W "sp|Q7Z794|K2C1B_HUMAN,sp|P04264|K2C1_HUMAN,sp|P35908|K22E_HUMAN" 3 1474.778 5.28 101615 14598 3 1474.779106 492.5999 "Keratin, type II cytoskeletal 1b OS=Homo sapiens OX=9606 GN=KRT77 PE=1 SV=3" 6 2568.9 - 543274 - - - 0.7547 - 1.411 0.095 - 62.1 1 2 0 0.0011 12 0 0 0 8.34E+06 1.58E+06 - - - 0.5532 1 221125_WJC_METTL3_EV_vs_WT_F07.14599.14599.4 9.33E-08 18/96 K.AVEHMFETEDGSKDEWR.G sp|Q9Y657|SPIN1_HUMAN 1 2064.8847 2.6 101616 14599 4 2064.888047 517.2285 Spindlin-1 OS=Homo sapiens OX=9606 GN=SPIN1 PE=1 SV=3 4.35 2569 - 463424 - - - 1.6117 - 4.029 0.618 - 345.1 1 2 1 0.0033 17 0 0 0 3.62E+07 1.39E+07 - - - 5.088 0.9994 221125_WJC_METTL3_EV_vs_WT_F07.14604.14604.3 2.77E-06 15/52 R.LKGSGNLEAIHIIK.K "sp|P78371|TCPB_HUMAN,tr|F8VQ14|F8VQ14_HUMAN,tr|F5GWF6|F5GWF6_HUMAN" 3 1491.8773 0.47 101619 14604 3 1491.878094 498.2997 T-complex protein 1 subunit beta OS=Homo sapiens OX=9606 GN=CCT2 PE=1 SV=4 8.6 2569.7 - 462090 - - - 0.5235 - 2.495 0.353 - 148.8 1 2 1 0.0008 14 0 0 0 1.64E+07 3.45E+07 - - - 4.9051 1 221125_WJC_METTL3_EV_vs_WT_F07.14605.14605.3 5.93E-12 24/76 K.AATGEEVSAEDLGGADLHC[160.03]R.K "sp|Q9HCC0|MCCB_HUMAN,tr|A0A804HJW5|A0A804HJW5_HUMAN,tr|A0A804HJC1|A0A804HJC1_HUMAN,tr|A0A804HK37|A0A804HK37_HUMAN,tr|A0A804HIH3|A0A804HIH3_HUMAN,tr|A0A804HJ24|A0A804HJ24_HUMAN,tr|A0A804HL02|A0A804HL02_HUMAN,tr|D6RD67|D6RD67_HUMAN,tr|A0A804HKE8|A0A804HKE8_HUMAN,tr|D6RDF7|D6RDF7_HUMAN,tr|A0A804HJ84|A0A804HJ84_HUMAN,tr|A0A804HJW2|A0A804HJW2_HUMAN,tr|A0A804HLJ9|A0A804HLJ9_HUMAN,tr|D6R9R1|D6R9R1_HUMAN,tr|A0A804HHS4|A0A804HHS4_HUMAN,tr|A0A804HJL2|A0A804HJL2_HUMAN,tr|A0A0S2Z5R4|A0A0S2Z5R4_HUMAN,tr|A0A804HJ31|A0A804HJ31_HUMAN" 18 2056.912 1.13 101620 14605 3 2056.911105 686.6446 "Methylcrotonoyl-CoA carboxylase beta chain, mitochondrial OS=Homo sapiens OX=9606 GN=MCCC2 PE=1 SV=1" 4.17 2569.7 - 2.21E+06 - - - -0.4337 - 4.443 0.543 - 619.5 1 2 0 -0.0009 20 0 0 0 3.74E+07 3.29E+07 - - - 8.2117 0.9992 221125_WJC_METTL3_EV_vs_WT_F07.14611.14611.4 7.31E-07 15/114 R.VVIVDPETNKEMSVQEAYKK.G sp|P15924|DESP_HUMAN 1 2306.1828 8.51 101624 14611 4 2306.192367 577.553 Desmoplakin OS=Homo sapiens OX=9606 GN=DSP PE=1 SV=3 4.87 2570.4 - 1.16E+06 - - - 4.1488 - 2.695 0.53 - 125.7 1 2 1 0.0096 20 0 0 0 3.30E+07 3.88E+06 - - - 4.1679 1 221125_WJC_METTL3_EV_vs_WT_F07.14615.14615.2 1.77E-07 16/32 Y.NQNLLTQQSIGAAGSQK[136.11].E "sp|Q92879|CELF1_HUMAN,tr|G5EA30|G5EA30_HUMAN" 2 1764.921 1.54 101628 14615 2 1764.919198 883.4678 CUGBP Elav-like family member 1 OS=Homo sapiens OX=9606 GN=CELF1 PE=1 SV=2 8.75 2571 - 318808 - - - -1.0068 - 3.284 0.608 - 862.5 1 1 0 -0.0018 17 0 0 0 6.06E+06 3.93E+06 - - - 6.4545 0.9946 221125_WJC_METTL3_EV_vs_WT_F07.14616.14616.4 0.00725 Nov-66 R.LKVNELREELQR.R "sp|Q9BUJ2|HNRL1_HUMAN,tr|A0A087X1I2|A0A087X1I2_HUMAN,tr|M0R247|M0R247_HUMAN" 3 1525.8576 1.5 101629 14616 4 1525.854511 382.4717 Heterogeneous nuclear ribonucleoprotein U-like protein 1 OS=Homo sapiens OX=9606 GN=HNRNPUL1 PE=1 SV=2 6.23 2571.1 - 314811 - - - -2.0507 - 1.951 0.301 - 99.9 1 2 2 -0.0031 12 0 0 0 1.11E+07 7.40E+06 - - - 2.098 0.9997 221125_WJC_METTL3_EV_vs_WT_F07.14618.14618.3 0.0293 Sep-32 R.EFADFEYRK.T "sp|Q8ND56|LS14A_HUMAN,tr|A0A140TA66|A0A140TA66_HUMAN" 2 1203.556 1.06 101631 14618 3 1203.557022 402.1926 Protein LSM14 homolog A OS=Homo sapiens OX=9606 GN=LSM14A PE=1 SV=3 4.68 2571.4 - 261723 - - - 0.8176 - 1.747 0.356 - 98.6 1 2 0 0.001 9 0 0 0 4.66E+06 4.40E+06 - - - 4.1902 0.9955 221125_WJC_METTL3_EV_vs_WT_F07.14623.14623.3 5.56E-06 14/64 Y.NQNLLTQQSIGAAGSQK.E "sp|Q92879|CELF1_HUMAN,tr|G5EA30|G5EA30_HUMAN" 2 1756.9068 0.64 101634 14623 3 1756.908286 586.6429 CUGBP Elav-like family member 1 OS=Homo sapiens OX=9606 GN=CELF1 PE=1 SV=2 8.75 2571.9 - 753886 - - - 0.86 - 2.761 0.45 - 266.5 1 1 0 0.0015 17 0 0 0 9.07E+06 1.43E+07 - - - 6.1223 0.9999 221125_WJC_METTL3_EV_vs_WT_F07.14624.14624.3 3.61E-09 20/56 K.K[136.11]NNVNVASLTQSEIR[166.11].D sp|Q6P2Q9|PRP8_HUMAN 1 1689.9129 0.92 101635 14624 3 1689.920559 564.3116 Pre-mRNA-processing-splicing factor 8 OS=Homo sapiens OX=9606 GN=PRPF8 PE=1 SV=2 8.75 2572 - 899195 - - - 4.5517 - 3.426 0.567 - 795.4 1 2 0 0.0077 15 0 0 0 1.40E+07 1.52E+07 - - - 8.0725 1 221125_WJC_METTL3_EV_vs_WT_F07.14626.14626.4 2.01E-10 22/96 K.AVEHMFETEDGSK[136.11]DEWR[166.11].G sp|Q9Y657|SPIN1_HUMAN 1 2082.9072 2.6 101637 14626 4 2082.910773 521.7341 Spindlin-1 OS=Homo sapiens OX=9606 GN=SPIN1 PE=1 SV=3 4.35 2572.2 - 803176 - - - 1.7207 - 4.254 0.658 - 530.8 1 2 1 0.0036 17 0 0 0 3.61E+07 1.39E+07 - - - 5.4549 0.9999 221125_WJC_METTL3_EV_vs_WT_F07.14628.14628.3 5.17E-06 19/52 R.KSEQEFSFDTPADR.S "sp|Q99590|SCAFB_HUMAN,tr|F8VXG7|F8VXG7_HUMAN" 2 1655.7427 1.31 101639 14628 3 1655.744347 552.9215 Protein SCAF11 OS=Homo sapiens OX=9606 GN=SCAF11 PE=1 SV=2 4.32 2572.4 - 580416 - - - 0.9766 - 2.942 0.4 - 375.6 1 2 0 0.0016 14 0 0 0 2.43E+07 1.86E+07 - - - 5.8669 1 221125_WJC_METTL3_EV_vs_WT_F07.14629.14629.2 2.82E-06 28-Dec R.AQVQEFC[160.03]DYGTK[136.11]EEC[160.03].M "sp|Q86U44|MTA70_HUMAN,tr|H0YFV6|H0YFV6_HUMAN" 2 1870.7593 0.001 101640 14629 2 1870.754101 936.3869 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 4 2572.6 - 475292 - - - -2.7871 - 2.544 0.618 - 293.1 1 1 1 -0.0052 15 0 0 0 0.00E+00 2.35E+07 - - - 5.8995 0.9996 221125_WJC_METTL3_EV_vs_WT_F07.14631.14631.4 0.000507 Dec-66 R.LK[136.11]VNELR[166.11]EELQR[166.11].R "sp|Q9BUJ2|HNRL1_HUMAN,tr|A0A087X1I2|A0A087X1I2_HUMAN,tr|M0R247|M0R247_HUMAN" 3 1553.8884 1.5 101642 14631 4 1553.886296 389.4794 Heterogeneous nuclear ribonucleoprotein U-like protein 1 OS=Homo sapiens OX=9606 GN=HNRNPUL1 PE=1 SV=2 6.23 2572.8 - 327195 - - - -1.3412 - 2.338 0.414 - 142.9 1 2 2 -0.0021 12 0 0 0 1.11E+07 7.40E+06 - - - 3.1503 1 221125_WJC_METTL3_EV_vs_WT_F07.14633.14633.3 7.26E-09 15/64 R.VHLPTQPAADTYSEFHK[136.11].H "sp|Q6W2J9|BCOR_HUMAN,tr|H7BZ37|H7BZ37_HUMAN,tr|H7C2V9|H7C2V9_HUMAN,tr|H7BYY2|H7BYY2_HUMAN,tr|H7C231|H7C231_HUMAN" 5 1947.957 1.68 101644 14633 3 1947.953615 650.3263 BCL-6 corepressor OS=Homo sapiens OX=9606 GN=BCOR PE=1 SV=1 5.99 2573.1 - 415990 - - - -1.7516 - 3.025 0.595 - 282.9 1 2 0 -0.0034 17 0 0 0 9.39E+06 5.58E+06 - - - 7.9691 1 221125_WJC_METTL3_EV_vs_WT_F07.14638.14638.4 2.00E-08 15/96 R.VHLPTQPAADTYSEFHK.H "sp|Q6W2J9|BCOR_HUMAN,tr|H7BZ37|H7BZ37_HUMAN,tr|H7C2V9|H7C2V9_HUMAN,tr|H7BYY2|H7BYY2_HUMAN,tr|H7C231|H7C231_HUMAN" 5 1939.9428 1.67 101647 14638 4 1939.946728 485.993 BCL-6 corepressor OS=Homo sapiens OX=9606 GN=BCOR PE=1 SV=1 5.99 2573.6 - 1.07E+06 - - - 2.0109 - 2.946 0.551 - 150.9 1 2 0 0.0039 17 0 0 0 1.32E+08 7.91E+07 - - - 4.396 0.9997 221125_WJC_METTL3_EV_vs_WT_F07.14639.14639.3 0.00037 Dec-52 R.LK[136.11]GSGNLEAIHIIK[136.11].K "sp|P78371|TCPB_HUMAN,tr|F8VQ14|F8VQ14_HUMAN,tr|F5GWF6|F5GWF6_HUMAN" 3 1507.9057 0.49 101648 14639 3 1507.906963 503.6425 T-complex protein 1 subunit beta OS=Homo sapiens OX=9606 GN=CCT2 PE=1 SV=4 8.6 2573.6 - 1.85E+06 - - - 0.829 - 2.605 0.401 - 114.2 1 2 1 0.0013 14 0 0 0 1.68E+07 3.45E+07 - - - 5.5548 0.9997 221125_WJC_METTL3_EV_vs_WT_F07.14640.14640.4 0.0183 Nov-90 R.GTFHDDR[166.11]DDGVDYWAK[136.11].R "tr|H0YF63|H0YF63_HUMAN,tr|E9PK91|E9PK91_HUMAN" 2 1913.8299 2.18 101649 14640 4 1913.830159 479.4648 Bcl-2-associated transcription factor 1 (Fragment) OS=Homo sapiens OX=9606 GN=BCLAF1 PE=1 SV=1 4.28 2573.8 - 607384 - - - 0.1223 - 2.161 0.458 - 86.2 1 2 1 0.0002 16 0 0 0 1.34E+09 6.15E+08 - - - 3.4838 0.9999 221125_WJC_METTL3_EV_vs_WT_F07.14641.14641.3 4.66E-07 17/64 R.VK[136.11]EGYVPQEEVPVYENK[136.11].Y sp|Q9BRP8|PYM1_HUMAN 1 2022.0281 0.34 101650 14641 3 2022.02777 675.0166 Partner of Y14 and mago OS=Homo sapiens OX=9606 GN=PYM1 PE=1 SV=1 4.49 2573.9 - 531881 - - - -0.1498 - 2.955 0.512 - 284.7 1 2 1 -0.0003 17 0 0 0 3.72E+06 1.09E+07 - - - 6.9855 0.9897 221125_WJC_METTL3_EV_vs_WT_F07.14642.14642.3 0.000285 16/64 Y.NQNLLTQQSIGAAGSQK[136.11].E "sp|Q92879|CELF1_HUMAN,tr|G5EA30|G5EA30_HUMAN" 2 1764.921 0.64 101651 14642 3 1764.922063 589.3143 CUGBP Elav-like family member 1 OS=Homo sapiens OX=9606 GN=CELF1 PE=1 SV=2 8.75 2574 - 511810 - - - 0.6165 - 2.581 0.383 - 312.8 1 1 0 0.0011 17 0 0 0 9.07E+06 1.43E+07 - - - 5.2052 0.9924 221125_WJC_METTL3_EV_vs_WT_F07.14644.14644.2 5.97E-06 14/32 Y.NQNLLTQQSIGAAGSQK.E "sp|Q92879|CELF1_HUMAN,tr|G5EA30|G5EA30_HUMAN" 2 1756.9068 1.54 101653 14644 2 1756.909032 879.4607 CUGBP Elav-like family member 1 OS=Homo sapiens OX=9606 GN=CELF1 PE=1 SV=2 8.75 2574.3 - 433448 - - - 1.2846 - 3.043 0.526 - 569.3 1 1 0 0.0023 17 0 0 0 6.06E+06 3.93E+06 - - - 5.6613 1 221125_WJC_METTL3_EV_vs_WT_F07.14645.14645.3 3.30E-15 25/64 K.AVEHMFETEDGSK[136.11]DEWR[166.11].G sp|Q9Y657|SPIN1_HUMAN 1 2082.9072 2.26 101654 14645 3 2082.909784 695.3097 Spindlin-1 OS=Homo sapiens OX=9606 GN=SPIN1 PE=1 SV=3 4.35 2574.4 - 428123 - - - 1.2459 - 4.838 0.718 - 1227.3 1 2 1 0.0026 17 0 0 0 1.54E+07 6.78E+06 - - - 10.527 1 221125_WJC_METTL3_EV_vs_WT_F07.14646.14646.3 0.000398 17/48 K.SHSGPIHVLLINK.E "sp|Q15329|E2F5_HUMAN,tr|E5RHD4|E5RHD4_HUMAN,tr|C9JYE9|C9JYE9_HUMAN,tr|H0YBK0|H0YBK0_HUMAN" 4 1413.8092 84.85 101655 14646 3 1413.807744 472.277 Transcription factor E2F5 OS=Homo sapiens OX=9606 GN=E2F5 PE=1 SV=1 8.51 2574.5 - 394802 - - - -1.0532 - 2.947 0.452 - 391.6 1 2 0 -0.0015 13 0 0 0 1.08E+07 1.28E+05 - - - 6.5093 0.9975 221125_WJC_METTL3_EV_vs_WT_F07.14651.14651.4 0.000256 Nov-78 R.QRPAEIKDYSPYFK.T sp|P02533|K1C14_HUMAN 1 1740.8835 578.11 101658 14651 4 1740.887065 436.2282 "Keratin, type I cytoskeletal 14 OS=Homo sapiens OX=9606 GN=KRT14 PE=1 SV=4" 8.43 2575.1 - 1.09E+06 - - - 2.0357 - 2.033 0.344 - 110.7 1 2 1 0.0035 14 0 0 0 4.42E+08 7.65E+05 - - - 2.4774 0.9997 221125_WJC_METTL3_EV_vs_WT_F07.14652.14652.4 0.000646 16/96 K.MNEYTVHLGSDTLGDRR.A "sp|P49862|KLK7_HUMAN,tr|M0QYU8|M0QYU8_HUMAN" 2 1962.9218 7.37 101659 14652 4 1962.928876 491.7377 Kallikrein-7 OS=Homo sapiens OX=9606 GN=KLK7 PE=1 SV=1 5.36 2575.2 - 659736 - - - 3.6181 - 2.946 0.458 - 263.8 1 2 0 0.0071 17 0 0 0 9.48E+06 1.29E+06 - - - 3.5856 0.9993 221125_WJC_METTL3_EV_vs_WT_F07.14654.14654.4 4.73E-07 15/96 K.NR[166.11]EELGFR[166.11]PEYSASQLK[136.11].G "sp|P09874|PARP1_HUMAN,tr|A0A7I2V5E9|A0A7I2V5E9_HUMAN,tr|A0A7I2V625|A0A7I2V625_HUMAN,tr|A0A7I2V3E1|A0A7I2V3E1_HUMAN" 4 2051.043 1.03 101661 14654 4 2051.047809 513.768 Poly [ADP-ribose] polymerase 1 OS=Homo sapiens OX=9606 GN=PARP1 PE=1 SV=4 6.23 2575.5 - 407403 - - - 2.3237 - 2.414 0.424 - 182.1 1 2 1 0.0048 17 0 0 0 3.39E+07 3.30E+07 - - - 3.2212 0.9999 221125_WJC_METTL3_EV_vs_WT_F07.14659.14659.4 1.83E-08 20/114 K.R[166.11]GLLQDDAHPTLVTYADHSK[136.11].L "sp|Q86U44|MTA70_HUMAN,tr|F5H6D8|F5H6D8_HUMAN,tr|H0YFV6|H0YFV6_HUMAN,tr|B4DTN4|B4DTN4_HUMAN" 4 2254.1461 0.01 101664 14659 4 2254.148569 564.5438 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 5.99 2576.1 - 2.07E+06 - - - 1.0887 - 3.808 0.437 - 363.3 1 2 0 0.0025 20 0 0 0 7.84E+05 5.76E+07 - - - 3.476 1 221125_WJC_METTL3_EV_vs_WT_F07.14660.14660.3 4.17E-07 24/64 K.AVEHMFETEDGSKDEWR.G sp|Q9Y657|SPIN1_HUMAN 1 2064.8847 2.26 101665 14660 3 2064.889902 689.3022 Spindlin-1 OS=Homo sapiens OX=9606 GN=SPIN1 PE=1 SV=3 4.35 2576.2 - 1.19E+06 - - - 2.5101 - 4.729 0.656 - 1133.3 1 2 1 0.0052 17 0 0 0 1.54E+07 6.78E+06 - - - 9.7775 1 221125_WJC_METTL3_EV_vs_WT_F07.14661.14661.3 1.43E-09 17/72 R.C[160.03]SVC[160.03]SEPIMPEPGRDETVR.V "sp|Q15942|ZYX_HUMAN,tr|H0Y2Y8|H0Y2Y8_HUMAN" 2 2217.9817 4.44 101666 14661 3 2217.985063 740.3345 Zyxin OS=Homo sapiens OX=9606 GN=ZYX PE=1 SV=1 4.41 2576.3 - 1.58E+06 - - - 1.528 - 3.087 0.668 - 300.4 1 2 1 0.0034 19 0 0 0 1.32E+08 2.97E+07 - - - 8.7559 0.9992 221125_WJC_METTL3_EV_vs_WT_F07.14662.14662.3 1.32E-08 16/56 K.DKYVGVSSDSVGGFR.Y sp|Q14677|EPN4_HUMAN 1 1571.758 0.07 101667 14662 3 1571.761462 524.9266 Clathrin interactor 1 OS=Homo sapiens OX=9606 GN=CLINT1 PE=1 SV=1 5.96 2576.4 - 1.13E+06 - - - 2.2115 - 2.867 0.371 - 292.7 1 2 1 0.0035 15 0 0 0 1.71E+07 2.56E+08 - - - 5.4237 1 221125_WJC_METTL3_EV_vs_WT_F07.14664.14664.3 4.61E-09 23/52 R.QRPAEIKDYSPYFK.T sp|P02533|K1C14_HUMAN 1 1740.8835 210.56 101669 14664 3 1740.888317 581.3018 "Keratin, type I cytoskeletal 14 OS=Homo sapiens OX=9606 GN=KRT14 PE=1 SV=4" 8.43 2576.6 - 1.07E+06 - - - 2.7549 - 3.533 0.626 - 772 1 2 1 0.0048 14 0 0 0 3.13E+08 1.49E+06 - - - 8.8722 1 221125_WJC_METTL3_EV_vs_WT_F07.14666.14666.3 6.35E-06 Nov-76 R.VSVC[160.03]AETYNPDEEEEDTDPR.V sp|P13861|KAP2_HUMAN 1 2353.9492 2.16 101671 14666 3 2353.952628 785.657 cAMP-dependent protein kinase type II-alpha regulatory subunit OS=Homo sapiens OX=9606 GN=PRKAR2A PE=1 SV=2 3.62 2576.8 - 483158 - - - 1.4435 - 2.401 0.587 - 47.3 1 2 0 0.0034 20 0 0 0 7.71E+06 3.56E+06 - - - 7.2084 0.9972 221125_WJC_METTL3_EV_vs_WT_F07.14668.14668.3 0.233 Jul-40 R.ERPAAISIEIK.S sp|Q15208|STK38_HUMAN 1 1225.703 5.18 101673 14668 3 1225.704888 409.575 Serine\threonine-protein kinase 38 OS=Homo sapiens OX=9606 GN=STK38 PE=1 SV=1 6.24 2577.1 - 269446 - - - 1.5102 - 1.459 0.29 - 59 1 2 0 0.0019 11 0 0 0 3.01E+06 5.80E+05 - - - 2.8458 0.9999 221125_WJC_METTL3_EV_vs_WT_F07.14669.14669.3 0.00026 Aug-76 R.VSVC[160.03]AETYNPDEEEEDTDPR[166.11].V sp|P13861|KAP2_HUMAN 1 2363.9575 2.16 101674 14669 3 2363.96374 788.9931 cAMP-dependent protein kinase type II-alpha regulatory subunit OS=Homo sapiens OX=9606 GN=PRKAR2A PE=1 SV=2 3.62 2577.2 - 228655 - - - 2.6396 - 1.848 0.55 - 34.3 1 2 0 0.0062 20 0 0 0 7.71E+06 3.56E+06 - - - 6.1601 1 221125_WJC_METTL3_EV_vs_WT_F07.14673.14673.3 1.27E-14 24/76 K.TC[160.03]TTVAFTQVNSEDK[136.11]GALAK[136.11].L "sp|P62424|RL7A_HUMAN,tr|Q5T8U2|Q5T8U2_HUMAN" 2 2156.0754 0.56 101676 14673 3 2156.077698 719.6991 60S ribosomal protein L7a OS=Homo sapiens OX=9606 GN=RPL7A PE=1 SV=2 5.73 2577.7 - 2.06E+06 - - - 1.0501 - 4.814 0.679 - 634.4 1 2 1 0.0023 20 0 0 0 2.18E+07 3.86E+07 - - - 9.9221 1 221125_WJC_METTL3_EV_vs_WT_F07.14674.14674.3 4.40E-07 20/76 K.TC[160.03]TTVAFTQVNSEDKGALAK.L "sp|P62424|RL7A_HUMAN,tr|Q5T8U2|Q5T8U2_HUMAN" 2 2140.047 0.57 101677 14674 3 2140.051461 714.3563 60S ribosomal protein L7a OS=Homo sapiens OX=9606 GN=RPL7A PE=1 SV=2 5.73 2577.8 - 1.36E+06 - - - 2.0686 - 3.773 0.602 - 526.9 1 2 1 0.0044 20 0 0 0 2.18E+07 3.82E+07 - - - 8.4719 0.9993 221125_WJC_METTL3_EV_vs_WT_F07.14675.14675.3 0.000323 13/44 R.LKVNELREELQR.R "sp|Q9BUJ2|HNRL1_HUMAN,tr|A0A087X1I2|A0A087X1I2_HUMAN,tr|M0R247|M0R247_HUMAN" 3 1525.8576 1.38 101678 14675 3 1525.860736 509.6265 Heterogeneous nuclear ribonucleoprotein U-like protein 1 OS=Homo sapiens OX=9606 GN=HNRNPUL1 PE=1 SV=2 6.23 2577.9 - 1.63E+06 - - - 2.029 - 2.1 0.435 - 227.7 1 2 2 0.0031 12 0 0 0 2.99E+07 2.17E+07 - - - 5.4455 0.9997 221125_WJC_METTL3_EV_vs_WT_F07.14677.14677.4 5.12E-08 14/96 K.NREELGFRPEYSASQLK.G "sp|P09874|PARP1_HUMAN,tr|A0A7I2V5E9|A0A7I2V5E9_HUMAN,tr|A0A7I2V625|A0A7I2V625_HUMAN,tr|A0A7I2V3E1|A0A7I2V3E1_HUMAN" 4 2023.0123 1.03 101680 14677 4 2023.018236 506.7604 Poly [ADP-ribose] polymerase 1 OS=Homo sapiens OX=9606 GN=PARP1 PE=1 SV=4 6.23 2578.1 - 860225 - - - 2.9328 - 2.912 0.542 - 159.6 1 2 1 0.0059 17 0 0 0 3.39E+07 3.30E+07 - - - 4.313 0.9953 221125_WJC_METTL3_EV_vs_WT_F07.14682.14682.3 1.23E-05 15/48 T.HLLEHITTNEDFR.A "sp|O75688|PPM1B_HUMAN,tr|B8ZZF0|B8ZZF0_HUMAN,tr|A0A3B3IS24|A0A3B3IS24_HUMAN,tr|C9JIR6|C9JIR6_HUMAN" 4 1623.8005 3.43 101685 14682 3 1623.80292 542.2741 Protein phosphatase 1B OS=Homo sapiens OX=9606 GN=PPM1B PE=1 SV=1 5.27 2578.7 - 514594 - - - 1.4786 - 2.701 0.466 - 366.8 1 1 0 0.0024 13 0 0 0 1.62E+07 4.71E+06 - - - 6.4288 0.9999 221125_WJC_METTL3_EV_vs_WT_F07.14684.14684.2 1.44E-07 Nov-38 R.LAEDAPNFDGPAAEGQPGQK.Q "sp|P78344|IF4G2_HUMAN,tr|H0YEC5|H0YEC5_HUMAN,tr|H0Y3P2|H0Y3P2_HUMAN,tr|H0YCH5|H0YCH5_HUMAN,tr|H0YD77|H0YD77_HUMAN,tr|D3DQV9|D3DQV9_HUMAN" 6 2010.9283 9.52 101687 14684 2 2010.929285 1006.4714 Eukaryotic translation initiation factor 4 gamma 2 OS=Homo sapiens OX=9606 GN=EIF4G2 PE=1 SV=1 3.92 2579 - 131386 - - - 0.4903 - 2.329 0.482 - 186.3 1 2 0 0.001 20 0 0 0 3.26E+06 3.43E+05 - - - 4.6793 0.9999 221125_WJC_METTL3_EV_vs_WT_F07.14687.14687.3 1.83E-05 18/64 K.NR[166.11]EELGFR[166.11]PEYSASQLK[136.11].G "sp|P09874|PARP1_HUMAN,tr|A0A7I2V5E9|A0A7I2V5E9_HUMAN,tr|A0A7I2V625|A0A7I2V625_HUMAN,tr|A0A7I2V3E1|A0A7I2V3E1_HUMAN" 4 2051.043 1.2 101688 14687 3 2051.043905 684.6883 Poly [ADP-ribose] polymerase 1 OS=Homo sapiens OX=9606 GN=PARP1 PE=1 SV=4 6.23 2579.4 - 1.44E+06 - - - 0.4203 - 2.816 0.496 - 265 1 2 1 0.0009 17 0 0 0 4.17E+07 3.46E+07 - - - 6.6852 0.9995 221125_WJC_METTL3_EV_vs_WT_F07.14688.14688.3 8.48E-09 15/60 R.QVEGMEDWKQDSQLQK.A "sp|P25311|ZA2G_HUMAN,tr|C9JEV0|C9JEV0_HUMAN" 2 1947.8996 31.09 101689 14688 3 1947.892329 650.3072 Zinc-alpha-2-glycoprotein OS=Homo sapiens OX=9606 GN=AZGP1 PE=1 SV=2 4.32 2579.4 - 971317 - - - -3.7538 - 2.682 0.573 - 229.2 1 2 1 -0.0073 16 0 0 0 4.54E+07 1.46E+06 - - - 7.4577 0.9999 221125_WJC_METTL3_EV_vs_WT_F07.14689.14689.2 3.44E-08 14/30 R.SSTPLPTISSSAENTR.Q "sp|P42166|LAP2A_HUMAN,sp|P42167|LAP2B_HUMAN,tr|G5E972|G5E972_HUMAN,tr|H0YJH7|H0YJH7_HUMAN" 4 1646.8111 1.14 101690 14689 2 1646.813061 824.4128 "Lamina-associated polypeptide 2, isoform alpha OS=Homo sapiens OX=9606 GN=TMPO PE=1 SV=2" 5.72 2579.6 - 710088 - - - 1.1641 - 2.418 0.549 - 346.4 1 2 0 0.0019 16 0 0 0 1.06E+08 9.30E+07 - - - 5.2661 0.9812 221125_WJC_METTL3_EV_vs_WT_F07.14691.14691.3 2.02E-05 Oct-56 R.AQVQEFC[160.03]DYGTK[136.11]EEC[160.03].M "sp|Q86U44|MTA70_HUMAN,tr|H0YFV6|H0YFV6_HUMAN" 2 1870.7593 0.01 101692 14691 3 1870.762915 624.5937 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 4 2579.8 - 495092 - - - 1.9244 - 1.908 0.604 - 105.3 1 1 1 0.0036 15 0 0 0 6.23E+04 1.14E+07 - - - 6.9588 0.9972 221125_WJC_METTL3_EV_vs_WT_F07.14692.14692.3 0.155 Oct-52 R.SSDPWSNSHFPHEN.- sp|Q92545|TM131_HUMAN 1 1639.6651 - 101693 14692 3 1639.669486 547.5623 Transmembrane protein 131 OS=Homo sapiens OX=9606 GN=TMEM131 PE=1 SV=3 5.14 2579.9 - 388636 - - - 2.6457 - 1.391 0.353 - 76.9 1 2 0 0.0043 14 0 0 0 - - - - - 3.3514 0.9993 221125_WJC_METTL3_EV_vs_WT_F07.14693.14693.3 0.00152 Nov-60 R.SSTPLPTISSSAENTR.Q "sp|P42166|LAP2A_HUMAN,sp|P42167|LAP2B_HUMAN,tr|G5E972|G5E972_HUMAN,tr|H0YJH7|H0YJH7_HUMAN" 4 1646.8111 1.51 101694 14693 3 1646.815366 549.9443 "Lamina-associated polypeptide 2, isoform alpha OS=Homo sapiens OX=9606 GN=TMPO PE=1 SV=2" 5.72 2580 - 305154 - - - 2.5637 - 2.154 0.351 - 101.5 1 2 0 0.0042 16 0 0 0 3.63E+07 2.40E+07 - - - 4.421 0.9999 221125_WJC_METTL3_EV_vs_WT_F07.14697.14697.2 7.07E-08 16/30 R.SSTPLPTISSSAENTR[166.11].Q "sp|P42166|LAP2A_HUMAN,sp|P42167|LAP2B_HUMAN,tr|G5E972|G5E972_HUMAN,tr|H0YJH7|H0YJH7_HUMAN" 4 1656.8194 1.14 101696 14697 2 1656.82001 829.417 "Lamina-associated polypeptide 2, isoform alpha OS=Homo sapiens OX=9606 GN=TMPO PE=1 SV=2" 5.72 2580.6 - 758328 - - - 0.3597 - 2.557 0.56 - 518.5 1 2 0 0.0006 16 0 0 0 1.06E+08 9.30E+07 - - - 5.4851 0.9998 221125_WJC_METTL3_EV_vs_WT_F07.14698.14698.3 3.87E-08 14/64 K.EKEAEDGIIAYDDC[160.03]GVK.L "sp|O75534|CSDE1_HUMAN,tr|E9PLT0|E9PLT0_HUMAN" 2 1910.8568 0.18 101697 14698 3 1910.859708 637.9595 Cold shock domain-containing protein E1 OS=Homo sapiens OX=9606 GN=CSDE1 PE=1 SV=2 4.02 2580.7 - 815849 - - - 1.5354 - 2.492 0.542 - 298.8 1 2 1 0.0029 17 0 0 0 9.22E+06 5.26E+07 - - - 6.8887 1 221125_WJC_METTL3_EV_vs_WT_F07.14700.14700.3 6.90E-07 Dec-52 R.K[136.11]SEQEFSFDTPADR[166.11].S "sp|Q99590|SCAFB_HUMAN,tr|F8VXG7|F8VXG7_HUMAN" 2 1673.7652 1.31 101699 14700 3 1673.768941 558.929 Protein SCAF11 OS=Homo sapiens OX=9606 GN=SCAF11 PE=1 SV=2 4.32 2580.8 - 678151 - - - 2.2351 - 2.49 0.541 - 141 1 2 0 0.0037 14 0 0 0 2.43E+07 1.86E+07 - - - 6.995 0.9998 221125_WJC_METTL3_EV_vs_WT_F07.14701.14701.3 7.68E-07 20/56 R.HRYEVVTELGPEEVR.W sp|Q8NEL9|DDHD1_HUMAN 1 1811.9166 1.42 101700 14701 3 1811.922021 604.9795 Phospholipase DDHD1 OS=Homo sapiens OX=9606 GN=DDHD1 PE=1 SV=2 4.91 2580.9 - 537281 - - - 2.9852 - 3.996 0.551 - 648.6 1 2 1 0.0054 15 0 0 0 1.06E+07 7.46E+06 - - - 8.2963 0.9969 221125_WJC_METTL3_EV_vs_WT_F07.14702.14702.3 0.0266 Oct-56 K.LKPNLGNGADLPNYR.W "sp|Q9Y266|NUDC_HUMAN,tr|A0A0A0MSS4|A0A0A0MSS4_HUMAN,tr|A0A0A0MSU9|A0A0A0MSU9_HUMAN" 3 1640.8635 1.1 101701 14702 3 1640.86941 547.9618 Nuclear migration protein nudC OS=Homo sapiens OX=9606 GN=NUDC PE=1 SV=1 8.59 2581.1 - 451994 - - - 3.6298 - 1.736 0.343 - 80.7 1 2 0 0.006 15 0 0 0 1.62E+07 1.47E+07 - - - 3.8017 0.9999 221125_WJC_METTL3_EV_vs_WT_F07.14704.14704.3 0.0218 16/72 K.TSPLVLDSNTVTQGHTAGR[166.11].K sp|Q92545|TM131_HUMAN 1 1962.9998 1.08 101703 14704 3 1963.00378 655.3406 Transmembrane protein 131 OS=Homo sapiens OX=9606 GN=TMEM131 PE=1 SV=3 6.41 2581.3 - 408584 - - - 2.0082 - 2.793 0.427 - 269.6 1 2 0 0.0039 19 0 0 0 1.30E+07 1.21E+07 - - - 5.823 0.9999 221125_WJC_METTL3_EV_vs_WT_F07.14711.14711.3 7.05E-05 14/92 R.VGDSTPVSEKPVSAAVDANASESP.- sp|Q9H8Y8|GORS2_HUMAN 1 2313.0972 1.8 101708 14711 3 2313.101188 772.0397 Golgi reassembly-stacking protein 2 OS=Homo sapiens OX=9606 GN=GORASP2 PE=1 SV=3 3.92 2582.2 - 627597 - - - 1.7176 - 2.447 0.457 - 114.8 1 2 0 0.004 24 0 0 0 2.01E+07 1.11E+07 - - - 5.7124 0.9998 221125_WJC_METTL3_EV_vs_WT_F07.14714.14714.4 2.78E-07 16/84 R.HRYEVVTELGPEEVR.W sp|Q8NEL9|DDHD1_HUMAN 1 1811.9166 1.58 101711 14714 4 1811.91902 453.9864 Phospholipase DDHD1 OS=Homo sapiens OX=9606 GN=DDHD1 PE=1 SV=2 4.91 2582.6 - 277104 - - - 1.329 - 3.042 0.45 - 353.3 1 2 1 0.0024 15 0 0 0 3.88E+06 2.45E+06 - - - 3.5402 0.9999 221125_WJC_METTL3_EV_vs_WT_F07.14717.14717.3 1.78E-06 19/56 R.HR[166.11]YEVVTELGPEEVR[166.11].W sp|Q8NEL9|DDHD1_HUMAN 1 1831.9332 1.45 101712 14717 3 1831.935204 611.6517 Phospholipase DDHD1 OS=Homo sapiens OX=9606 GN=DDHD1 PE=1 SV=2 4.91 2583 - 546082 - - - 1.1201 - 4.195 0.53 - 561.4 1 2 1 0.0021 15 0 0 0 1.06E+07 7.32E+06 - - - 8.19 0.9995 221125_WJC_METTL3_EV_vs_WT_F07.14718.14718.3 2.99E-05 14/76 K.KPSAAPEAGASALPNPPALK.K "sp|P39880|CUX1_HUMAN,tr|A0A2R8Y852|A0A2R8Y852_HUMAN,tr|A0A2R8YDI1|A0A2R8YDI1_HUMAN" 3 1886.0262 1.6 101713 14718 3 1886.032416 629.6827 Homeobox protein cut-like 1 OS=Homo sapiens OX=9606 GN=CUX1 PE=1 SV=3 8.59 2583.2 - 391882 - - - 3.316 - 2.344 0.41 - 129.9 1 2 0 0.0063 20 0 0 0 8.23E+06 5.15E+06 - - - 5.176 0.9808 221125_WJC_METTL3_EV_vs_WT_F07.14727.14727.4 0.000987 14/90 K.EQPRPDVPITDQHILR.E "sp|Q5D1E8|ZC12A_HUMAN,tr|A0A1W2PQC8|A0A1W2PQC8_HUMAN" 2 1913.0119 3.31 101720 14727 4 1913.014074 479.2603 Endoribonuclease ZC3H12A OS=Homo sapiens OX=9606 GN=ZC3H12A PE=1 SV=1 5.38 2584.4 - 461724 - - - 1.1317 - 2.22 0.165 - 142.1 1 2 0 0.0022 16 0 0 0 8.54E+06 2.58E+06 - - - 0.9425 0.9986 221125_WJC_METTL3_EV_vs_WT_F07.14729.14729.3 0.00337 Sep-36 K.NYGFVHIEDK.T "sp|Q9BWF3|RBM4_HUMAN,sp|Q9BQ04|RBM4B_HUMAN,tr|E9PM61|E9PM61_HUMAN,tr|D6R9K7|D6R9K7_HUMAN,tr|J3QRR5|J3QRR5_HUMAN,tr|E9PB51|E9PB51_HUMAN,tr|U3KQD5|U3KQD5_HUMAN,tr|E9PLB0|E9PLB0_HUMAN" 8 1220.5826 1.54 101722 14729 3 1220.582359 407.8681 RNA-binding protein 4 OS=Homo sapiens OX=9606 GN=RBM4 PE=1 SV=1 5.32 2584.6 - 321525 - - - -0.1876 - 2.03 0.223 - 141.5 1 2 0 -0.0002 10 0 0 0 7.70E+06 4.99E+06 - - - 3.0939 0.9997 221125_WJC_METTL3_EV_vs_WT_F07.14731.14731.3 0.000469 Sep-36 K.NYGFVHIEDK[136.11].T "sp|Q9BWF3|RBM4_HUMAN,sp|Q9BQ04|RBM4B_HUMAN,tr|E9PM61|E9PM61_HUMAN,tr|D6R9K7|D6R9K7_HUMAN,tr|J3QRR5|J3QRR5_HUMAN,tr|E9PB51|E9PB51_HUMAN,tr|U3KQD5|U3KQD5_HUMAN,tr|E9PLB0|E9PLB0_HUMAN" 8 1228.5968 1.55 101724 14731 3 1228.598037 410.5395 RNA-binding protein 4 OS=Homo sapiens OX=9606 GN=RBM4 PE=1 SV=1 5.32 2584.9 - 292252 - - - 1.0166 - 2.035 0.328 - 131.6 1 2 0 0.0012 10 0 0 0 7.72E+06 4.99E+06 - - - 4.2715 0.9998 221125_WJC_METTL3_EV_vs_WT_F07.14739.14739.3 0.000132 Oct-68 K.MTLDQQHIETPGQNIPTK[136.11].V "sp|Q2KHR3|QSER1_HUMAN,tr|A0A3B3IRW6|A0A3B3IRW6_HUMAN" 2 2058.0295 2.34 101730 14739 3 2058.028744 687.0171 Glutamine and serine-rich protein 1 OS=Homo sapiens OX=9606 GN=QSER1 PE=1 SV=3 5.3 2585.9 - 322928 - - - -0.3868 - 1.961 0.403 - 86.9 1 2 0 -0.0008 18 0 0 0 2.66E+07 1.13E+07 - - - 4.7098 0.9974 221125_WJC_METTL3_EV_vs_WT_F07.14740.14740.4 0.00719 Oct-96 R.IPEPQK[136.11]PQLK[136.11]PPEDIVR[166.11].S "sp|Q07157|ZO1_HUMAN,tr|A0A087X0K9|A0A087X0K9_HUMAN,tr|G5E9E7|G5E9E7_HUMAN,tr|A0A0G2JNH2|A0A0G2JNH2_HUMAN,tr|G3V1L9|G3V1L9_HUMAN,tr|A0A7I2V5U5|A0A7I2V5U5_HUMAN" 6 2009.152 1.32 101731 14740 4 2009.15931 503.2953 Tight junction protein ZO-1 OS=Homo sapiens OX=9606 GN=TJP1 PE=1 SV=3 6.18 2586 - 201079 - - - 3.6473 - 2.052 0.329 - 50.6 1 2 0 0.0073 17 0 0 0 1.69E+07 1.29E+07 - - - 2.3372 0.9945 221125_WJC_METTL3_EV_vs_WT_F07.14741.14741.3 0.161 Aug-32 K.KNNLRDWLR.V "sp|Q6P5R6|RL22L_HUMAN,sp|P35268|RL22_HUMAN,tr|H0Y8C2|H0Y8C2_HUMAN,tr|K7ERI7|K7ERI7_HUMAN,tr|K7EMH1|K7EMH1_HUMAN,tr|K7ELC4|K7ELC4_HUMAN,tr|C9JYQ9|C9JYQ9_HUMAN" 7 1213.668 1.24 101732 14741 3 1213.66892 405.5633 60S ribosomal protein L22-like 1 OS=Homo sapiens OX=9606 GN=RPL22L1 PE=1 SV=2 10.84 2586.1 - 183391 - - - 0.7671 - 1.585 0.292 - 104.6 1 2 1 0.0009 9 0 0 0 6.18E+06 4.98E+06 - - - 3.1834 0.9999 221125_WJC_METTL3_EV_vs_WT_F07.14753.14753.4 3.20E-05 18/84 R.VLSAPPHFHFGQTNR.T sp|P26641|EF1G_HUMAN 1 1706.8641 1.01 101740 14753 4 1706.868316 427.7233 Elongation factor 1-gamma OS=Homo sapiens OX=9606 GN=EEF1G PE=1 SV=3 9.73 2587.6 - 1.28E+06 - - - 2.4566 - 3.013 0.436 - 433.5 1 2 0 0.0042 15 0 0 0 2.11E+08 2.10E+08 - - - 3.4144 1 221125_WJC_METTL3_EV_vs_WT_F07.14754.14754.3 2.31E-07 25/56 R.R[166.11]VHVTQEDFEMAVAK[136.11].V sp|P62195|PRS8_HUMAN 1 1776.8948 0.74 101741 14754 3 1776.898032 593.3055 26S proteasome regulatory subunit 8 OS=Homo sapiens OX=9606 GN=PSMC5 PE=1 SV=1 5.45 2587.7 - 999354 - - - 1.8335 - 4.596 0.64 - 1153.2 1 2 0 0.0033 15 0 0 0 7.98E+06 1.08E+07 - - - 9.6542 0.9083 221125_WJC_METTL3_EV_vs_WT_F07.14757.14757.3 0.28 Nov-56 L.PPPPALEDLPLPPPK.E sp|Q702N8|XIRP1_HUMAN 1 1576.8865 83.78 101744 14757 3 1576.884983 526.6361 Xin actin-binding repeat-containing protein 1 OS=Homo sapiens OX=9606 GN=XIRP1 PE=1 SV=1 4.37 2588 - 715484 - - - -0.95 - 1.887 0.282 - 139.9 1 1 0 -0.0015 15 0 0 0 3.08E+07 3.68E+05 - - - 3.3405 0.9994 221125_WJC_METTL3_EV_vs_WT_F07.14761.14761.4 5.52E-06 20/102 K.AKLEATLQEEAAIQQEHR.E sp|O95202|LETM1_HUMAN 1 2064.06 1.22 101748 14761 4 2064.065452 517.0223 Mitochondrial proton\calcium exchanger protein OS=Homo sapiens OX=9606 GN=LETM1 PE=1 SV=1 4.91 2588.5 - 308958 - - - 2.6501 - 3.731 0.44 - 405.1 1 2 1 0.0055 18 0 0 0 5.51E+06 4.54E+06 - - - 3.5053 0.9999 221125_WJC_METTL3_EV_vs_WT_F07.14767.14767.3 1.26E-06 18/56 R.VLSAPPHFHFGQTNR.T sp|P26641|EF1G_HUMAN 1 1706.8641 1.11 101752 14767 3 1706.869559 569.962 Elongation factor 1-gamma OS=Homo sapiens OX=9606 GN=EEF1G PE=1 SV=3 9.73 2589.2 - 1.65E+06 - - - 3.1848 - 3.058 0.472 - 460.7 1 2 0 0.0054 15 0 0 0 1.03E+08 9.23E+07 - - - 6.7175 0.9999 221125_WJC_METTL3_EV_vs_WT_F07.14768.14768.4 2.61E-06 20/102 K.AK[136.11]LEATLQEEAAIQQEHR[166.11].E sp|O95202|LETM1_HUMAN 1 2082.0825 1.22 101753 14768 4 2082.086038 521.5279 Mitochondrial proton\calcium exchanger protein OS=Homo sapiens OX=9606 GN=LETM1 PE=1 SV=1 4.91 2589.3 - 589949 - - - 1.7223 - 3.459 0.54 - 421.4 1 2 1 0.0036 18 0 0 0 5.31E+06 4.37E+06 - - - 4.3503 0.9982 221125_WJC_METTL3_EV_vs_WT_F07.14771.14771.4 0.000715 Oct-90 R.GTFHDDRDDGVDYWAK.R "tr|H0YF63|H0YF63_HUMAN,tr|E9PK91|E9PK91_HUMAN" 2 1895.8075 2.3 101756 14771 4 1895.814077 474.9591 Bcl-2-associated transcription factor 1 (Fragment) OS=Homo sapiens OX=9606 GN=BCLAF1 PE=1 SV=1 4.28 2589.6 - 940697 - - - 3.493 - 1.754 0.431 - 62.6 1 2 1 0.0066 16 0 0 0 1.95E+07 8.46E+06 - - - 3.1735 1 221125_WJC_METTL3_EV_vs_WT_F07.14772.14772.3 5.85E-08 25/68 K.AKLEATLQEEAAIQQEHR.E sp|O95202|LETM1_HUMAN 1 2064.06 1.14 101757 14772 3 2064.063083 689.0273 Mitochondrial proton\calcium exchanger protein OS=Homo sapiens OX=9606 GN=LETM1 PE=1 SV=1 4.91 2589.7 - 481044 - - - 1.5024 - 4.507 0.645 - 1092.4 1 2 1 0.0031 18 0 0 0 5.09E+06 4.46E+06 - - - 9.4794 0.9999 221125_WJC_METTL3_EV_vs_WT_F07.14773.14773.3 0.00118 14/68 K.SSQIGAVVSHQSSVIPDR[166.11].E "sp|Q9NVS9|PNPO_HUMAN,tr|J3QQZ9|J3QQZ9_HUMAN,tr|J3QQV6|J3QQV6_HUMAN" 3 1875.9678 0.61 101758 14773 3 1875.966415 626.3299 Pyridoxine-5'-phosphate oxidase OS=Homo sapiens OX=9606 GN=PNPO PE=1 SV=1 6.46 2589.9 - 413740 - - - -0.7431 - 2.788 0.396 - 210.3 1 2 0 -0.0014 18 0 0 0 4.93E+06 8.14E+06 - - - 5.5078 0.9999 221125_WJC_METTL3_EV_vs_WT_F07.14774.14774.4 0.00126 14/96 R.IPEPQKPQLKPPEDIVR.S "sp|Q07157|ZO1_HUMAN,tr|A0A087X0K9|A0A087X0K9_HUMAN,tr|G5E9E7|G5E9E7_HUMAN,tr|A0A0G2JNH2|A0A0G2JNH2_HUMAN,tr|G3V1L9|G3V1L9_HUMAN,tr|A0A7I2V5U5|A0A7I2V5U5_HUMAN" 6 1983.1153 1.29 101759 14774 4 1983.119215 496.7861 Tight junction protein ZO-1 OS=Homo sapiens OX=9606 GN=TJP1 PE=1 SV=3 6.18 2590 - 383054 - - - 1.9681 - 2.856 0.425 - 132.1 1 2 0 0.0039 17 0 0 0 1.66E+07 1.29E+07 - - - 3.2885 0.9909 221125_WJC_METTL3_EV_vs_WT_F07.14777.14777.3 0.000183 Aug-40 Q.PAADTYSEFHK.H "sp|Q6W2J9|BCOR_HUMAN,tr|H7BZ37|H7BZ37_HUMAN,tr|H7C2V9|H7C2V9_HUMAN,tr|H7BYY2|H7BYY2_HUMAN,tr|H7C231|H7C231_HUMAN" 5 1264.5724 0.1 101762 14777 3 1264.571687 422.5314 BCL-6 corepressor OS=Homo sapiens OX=9606 GN=BCOR PE=1 SV=1 5.33 2590.4 - 171878 - - - -0.5773 - 1.705 0.473 - 57.3 1 1 0 -0.0007 11 0 0 0 2.25E+06 2.17E+07 - - - 5.329 1 221125_WJC_METTL3_EV_vs_WT_F07.14783.14783.3 7.62E-09 17/64 R.VHLPTQPAADTYSEFHK[136.11].H "sp|Q6W2J9|BCOR_HUMAN,tr|H7BZ37|H7BZ37_HUMAN,tr|H7C2V9|H7C2V9_HUMAN,tr|H7BYY2|H7BYY2_HUMAN,tr|H7C231|H7C231_HUMAN" 5 1947.957 2.71 101766 14783 3 1947.959498 650.3263 BCL-6 corepressor OS=Homo sapiens OX=9606 GN=BCOR PE=1 SV=1 5.99 2591.1 - 2.52E+06 - - - 1.2685 - 3.461 0.607 - 371.1 1 2 0 0.0025 17 0 0 0 7.03E+07 2.60E+07 - - - 8.4433 1 221125_WJC_METTL3_EV_vs_WT_F07.14784.14784.3 6.11E-05 17/60 R.SSTPLPTISSSAENTR[166.11].Q "sp|P42166|LAP2A_HUMAN,sp|P42167|LAP2B_HUMAN,tr|G5E972|G5E972_HUMAN,tr|H0YJH7|H0YJH7_HUMAN" 4 1656.8194 1.47 101767 14784 3 1656.821312 553.2804 "Lamina-associated polypeptide 2, isoform alpha OS=Homo sapiens OX=9606 GN=TMPO PE=1 SV=2" 5.72 2591.1 - 1.38E+06 - - - 1.1456 - 3.024 0.486 - 456.5 1 2 0 0.0019 16 0 0 0 3.46E+07 2.35E+07 - - - 6.7972 1 221125_WJC_METTL3_EV_vs_WT_F07.14787.14787.3 1.55E-08 18/64 K.HQAFEAEVQANSGAIVK.L "sp|Q13813|SPTN1_HUMAN,tr|A0A0D9SFF6|A0A0D9SFF6_HUMAN,tr|A0A0D9SF54|A0A0D9SF54_HUMAN,tr|A0A0D9SGF6|A0A0D9SGF6_HUMAN,tr|A0A5F9ZHC3|A0A5F9ZHC3_HUMAN" 5 1797.901 1.73 101770 14787 3 1797.905786 600.3076 "Spectrin alpha chain, non-erythrocytic 1 OS=Homo sapiens OX=9606 GN=SPTAN1 PE=1 SV=3" 5.4 2591.5 - 691758 - - - 2.6831 - 3.04 0.626 - 361.5 1 2 0 0.0048 17 0 0 0 2.76E+07 1.60E+07 - - - 8.3268 1 221125_WJC_METTL3_EV_vs_WT_F07.14799.14799.4 3.70E-06 19/84 R.VLSAPPHFHFGQTNR[166.11].T sp|P26641|EF1G_HUMAN 1 1716.8724 1.02 101780 14799 4 1716.873714 430.2254 Elongation factor 1-gamma OS=Homo sapiens OX=9606 GN=EEF1G PE=1 SV=3 9.73 2593 - 1.03E+07 - - - 0.7694 - 3.335 0.506 - 470.2 1 2 0 0.0013 15 0 0 0 2.75E+08 2.70E+08 - - - 4.0608 0.9999 221125_WJC_METTL3_EV_vs_WT_F07.14800.14800.3 7.13E-08 15/64 K.STLPDVVSHPSDASSYR[166.11].R sp|P31271|HXA13_HUMAN 1 1826.8674 2.42 101781 14800 3 1826.859812 609.9631 Homeobox protein Hox-A13 OS=Homo sapiens OX=9606 GN=HOXA13 PE=1 SV=3 5.19 2593 - 1.03E+06 - - - -4.1678 - 3.096 0.575 - 252 1 2 0 -0.0076 17 0 0 0 7.89E+07 3.26E+07 - - - 7.8036 0.9998 221125_WJC_METTL3_EV_vs_WT_F07.14803.14803.4 0.00021 16/96 R.RFDAERPVDC[160.03]SVIVVNK.Q "sp|Q9HCD5|NCOA5_HUMAN,tr|Q5JY17|Q5JY17_HUMAN" 2 2003.0258 1.88 101784 14803 4 2003.028423 501.7637 Nuclear receptor coactivator 5 OS=Homo sapiens OX=9606 GN=NCOA5 PE=1 SV=2 6.11 2593.3 - 803314 - - - 1.2871 - 2.662 0.378 - 228.1 1 2 0 0.0026 17 0 0 0 4.17E+07 2.22E+07 - - - 2.8553 0.9999 221125_WJC_METTL3_EV_vs_WT_F07.14806.14806.3 0.000146 16/64 R.R[166.11]FDAER[166.11]PVDC[160.03]SVIVVNK[136.11].Q "sp|Q9HCD5|NCOA5_HUMAN,tr|Q5JY17|Q5JY17_HUMAN" 2 2031.0566 1.97 101787 14806 3 2031.056233 678.0261 Nuclear receptor coactivator 5 OS=Homo sapiens OX=9606 GN=NCOA5 PE=1 SV=2 6.11 2593.6 - 525564 - - - -0.1733 - 2.794 0.394 - 352.9 1 2 0 -0.0004 17 0 0 0 4.04E+07 2.05E+07 - - - 5.5283 1 221125_WJC_METTL3_EV_vs_WT_F07.14813.14813.3 2.48E-05 17/64 R.RFDAERPVDC[160.03]SVIVVNK.Q "sp|Q9HCD5|NCOA5_HUMAN,tr|Q5JY17|Q5JY17_HUMAN" 2 2003.0258 1.97 101792 14813 3 2003.028501 668.6826 Nuclear receptor coactivator 5 OS=Homo sapiens OX=9606 GN=NCOA5 PE=1 SV=2 6.11 2594.5 - 1.42E+06 - - - 1.326 - 2.865 0.488 - 391.9 1 2 0 0.0027 17 0 0 0 4.03E+07 2.05E+07 - - - 6.6391 1 221125_WJC_METTL3_EV_vs_WT_F07.14814.14814.4 1.64E-08 20/96 R.R[166.11]FDAER[166.11]PVDC[160.03]SVIVVNK[136.11].Q "sp|Q9HCD5|NCOA5_HUMAN,tr|Q5JY17|Q5JY17_HUMAN" 2 2031.0566 1.88 101793 14814 4 2031.056149 508.7714 Nuclear receptor coactivator 5 OS=Homo sapiens OX=9606 GN=NCOA5 PE=1 SV=2 6.11 2594.6 - 1.23E+06 - - - -0.2147 - 2.947 0.496 - 381.8 1 2 0 -0.0004 17 0 0 0 4.18E+07 2.22E+07 - - - 3.9183 0.9872 221125_WJC_METTL3_EV_vs_WT_F07.14815.14815.3 0.0179 14/52 V.LSAPPHFHFGQTNR[166.11].T sp|P26641|EF1G_HUMAN 1 1617.804 1.51 101794 14815 3 1617.801716 540.2753 Elongation factor 1-gamma OS=Homo sapiens OX=9606 GN=EEF1G PE=1 SV=3 9.76 2594.7 - 554687 - - - -1.3988 - 2.831 0.348 - 331.5 1 1 0 -0.0023 14 0 0 0 1.18E+07 7.82E+06 - - - 5.1847 1 221125_WJC_METTL3_EV_vs_WT_F07.14821.14821.4 3.77E-07 17/84 K.THINIVVIGHVDSGK[136.11].S "sp|Q05639|EF1A2_HUMAN,sp|P68104|EF1A1_HUMAN,sp|Q5VTE0|EF1A3_HUMAN,tr|A0A2R8Y488|A0A2R8Y488_HUMAN,tr|A0A2R8YDN5|A0A2R8YDN5_HUMAN,tr|A0A7I2V659|A0A7I2V659_HUMAN,tr|A0A7I2V3H3|A0A7I2V3H3_HUMAN,tr|Q5JR01|Q5JR01_HUMAN,tr|A0A2U3TZH3|A0A2U3TZH3_HUMAN,tr|A0A7I2V5N4|A0A7I2V5N4_HUMAN,tr|A0A087WVQ9|A0A087WVQ9_HUMAN,tr|A6PW80|A6PW80_HUMAN,tr|A0A087WV01|A0A087WV01_HUMAN,tr|A0A2R8Y660|A0A2R8Y660_HUMAN,tr|A0A6Q8PFK6|A0A6Q8PFK6_HUMAN" 15 1595.8875 0.38 101798 14821 4 1595.886262 399.9791 Elongation factor 1-alpha 2 OS=Homo sapiens OX=9606 GN=EEF1A2 PE=1 SV=1 6.61 2595.5 - 1.03E+06 - - - -0.7695 - 3.353 0.566 - 402.7 1 2 0 -0.0012 15 0 0 0 2.49E+08 6.59E+08 - - - 4.585 0.998 221125_WJC_METTL3_EV_vs_WT_F07.14822.14822.3 1.66E-06 15/48 L.SAPPHFHFGQTNR.T sp|P26641|EF1G_HUMAN 1 1494.7116 1.14 101799 14822 3 1494.711548 499.2445 Elongation factor 1-gamma OS=Homo sapiens OX=9606 GN=EEF1G PE=1 SV=3 9.51 2595.6 - 786926 - - - -0.0649 - 2.86 0.514 - 398.5 1 1 0 -0.0001 13 0 0 0 1.65E+07 1.45E+07 - - - 7.1196 1 221125_WJC_METTL3_EV_vs_WT_F07.14823.14823.3 0.000268 17/52 K.LGAQLADLHLDNK[136.11]K[136.11].L "sp|Q9HA64|KT3K_HUMAN,tr|I3L2G3|I3L2G3_HUMAN,tr|I3L139|I3L139_HUMAN" 3 1550.8751 0.28 101800 14823 3 1550.875133 517.9657 Ketosamine-3-kinase OS=Homo sapiens OX=9606 GN=FN3KRP PE=1 SV=2 6.75 2595.7 - 756961 - - - -0.0052 - 3.344 0.425 - 472.2 1 2 0 0 14 0 0 0 4.03E+06 1.41E+07 - - - 6.4864 0.995 221125_WJC_METTL3_EV_vs_WT_F07.14824.14824.3 7.01E-06 13/52 V.LSAPPHFHFGQTNR.T sp|P26641|EF1G_HUMAN 1 1607.7957 1.59 101801 14824 3 1607.794625 536.9392 Elongation factor 1-gamma OS=Homo sapiens OX=9606 GN=EEF1G PE=1 SV=3 9.76 2595.9 - 492748 - - - -0.6742 - 2.793 0.421 - 242.7 1 1 0 -0.0011 14 0 0 0 1.37E+07 8.66E+06 - - - 5.963 0.9999 221125_WJC_METTL3_EV_vs_WT_F07.14826.14826.3 1.96E-07 22/76 R.LQQQAALSPTTAPAVSSVSK.Q "sp|Q8WXI9|P66B_HUMAN,tr|A0A0U1RRM1|A0A0U1RRM1_HUMAN,tr|A0A0U1RR30|A0A0U1RR30_HUMAN" 3 1983.0637 1.92 101803 14826 3 1983.056916 662.0285 Transcriptional repressor p66-beta OS=Homo sapiens OX=9606 GN=GATAD2B PE=1 SV=1 8.75 2596.1 - 326590 - - - -3.4058 - 3.773 0.511 - 380.8 1 2 0 -0.0068 20 0 0 0 8.14E+06 4.24E+06 - - - 7.4567 1 221125_WJC_METTL3_EV_vs_WT_F07.14827.14827.3 3.40E-06 Nov-48 R.R[166.11]LESIATTLVSHK[136.11].A sp|Q9P2R3|ANFY1_HUMAN 1 1471.8477 1.36 101804 14827 3 1471.847112 491.6232 Rabankyrin-5 OS=Homo sapiens OX=9606 GN=ANKFY1 PE=1 SV=2 8.75 2596.2 - 318185 - - - -0.4314 - 2.652 0.425 - 180.2 1 2 0 -0.0006 13 0 0 0 5.17E+06 3.80E+06 - - - 5.9225 1 221125_WJC_METTL3_EV_vs_WT_F07.14828.14828.3 5.14E-07 16/76 R.LQQQAALSPTTAPAVSSVSK[136.11].Q "sp|Q8WXI9|P66B_HUMAN,tr|A0A0U1RRM1|A0A0U1RRM1_HUMAN,tr|A0A0U1RR30|A0A0U1RR30_HUMAN" 3 1991.0779 1.92 101805 14828 3 1991.075842 664.6999 Transcriptional repressor p66-beta OS=Homo sapiens OX=9606 GN=GATAD2B PE=1 SV=1 8.75 2596.4 - 254013 - - - -1.0185 - 3.306 0.508 - 239.3 1 2 0 -0.002 20 0 0 0 8.14E+06 4.24E+06 - - - 7.104 0.9998 221125_WJC_METTL3_EV_vs_WT_F07.14833.14833.3 0.00364 Oct-40 K.IWHHTFYNELR.V "sp|Q6S8J3|POTEE_HUMAN,sp|P63261|ACTG_HUMAN,sp|P68133|ACTS_HUMAN,sp|Q9BYX7|ACTBM_HUMAN,sp|P68032|ACTC_HUMAN,sp|P60709|ACTB_HUMAN,sp|A5A3E0|POTEF_HUMAN,sp|P0CG38|POTEI_HUMAN,sp|P0CG39|POTEJ_HUMAN,tr|A0A804GS07|A0A804GS07_HUMAN,tr|I3L3I0|I3L3I0_HUMAN,tr|G5E9R0|G5E9R0_HUMAN,tr|E7EVS6|E7EVS6_HUMAN,tr|A0A6Q8PFE4|A0A6Q8PFE4_HUMAN,tr|J3KT65|J3KT65_HUMAN,tr|I3L3R2|I3L3R2_HUMAN,tr|K7EM38|K7EM38_HUMAN,tr|A0A6Q8PH58|A0A6Q8PH58_HUMAN,tr|I3L1U9|I3L1U9_HUMAN,tr|A0A804HKV3|A0A804HKV3_HUMAN,tr|A0A2R8Y793|A0A2R8Y793_HUMAN,tr|I3L4N8|I3L4N8_HUMAN,tr|C9JUM1|C9JUM1_HUMAN,tr|C9JZR7|C9JZR7_HUMAN,tr|A0A2R8YGF8|A0A2R8YGF8_HUMAN,tr|A6NL76|A6NL76_HUMAN" 26 1514.7419 0.94 101808 14833 3 1514.743093 505.9212 POTE ankyrin domain family member E OS=Homo sapiens OX=9606 GN=POTEE PE=2 SV=3 6.92 2597 - 2.29E+06 - - - 0.7995 - 1.886 0.393 - 168.8 1 2 0 0.0012 11 0 0 0 4.12E+07 4.37E+07 - - - 4.7236 1 221125_WJC_METTL3_EV_vs_WT_F07.14834.14834.3 6.39E-10 19/56 K.THINIVVIGHVDSGK.S "sp|Q05639|EF1A2_HUMAN,sp|P68104|EF1A1_HUMAN,sp|Q5VTE0|EF1A3_HUMAN,tr|A0A2R8Y488|A0A2R8Y488_HUMAN,tr|A0A2R8YDN5|A0A2R8YDN5_HUMAN,tr|A0A7I2V659|A0A7I2V659_HUMAN,tr|A0A7I2V3H3|A0A7I2V3H3_HUMAN,tr|Q5JR01|Q5JR01_HUMAN,tr|A0A2U3TZH3|A0A2U3TZH3_HUMAN,tr|A0A7I2V5N4|A0A7I2V5N4_HUMAN,tr|A0A087WVQ9|A0A087WVQ9_HUMAN,tr|A6PW80|A6PW80_HUMAN,tr|A0A087WV01|A0A087WV01_HUMAN,tr|A0A2R8Y660|A0A2R8Y660_HUMAN,tr|A0A6Q8PFK6|A0A6Q8PFK6_HUMAN" 15 1587.8733 0.38 101809 14834 3 1587.875176 530.2984 Elongation factor 1-alpha 2 OS=Homo sapiens OX=9606 GN=EEF1A2 PE=1 SV=1 6.61 2597.1 - 1.73E+06 - - - 1.1878 - 3.827 0.504 - 731.2 1 2 0 0.0019 15 0 0 0 4.92E+08 1.30E+09 - - - 7.6606 0.9982 221125_WJC_METTL3_EV_vs_WT_F07.14838.14838.4 0.000391 16/78 K.LGAQLADLHLDNK[136.11]K[136.11].L "sp|Q9HA64|KT3K_HUMAN,tr|I3L2G3|I3L2G3_HUMAN,tr|I3L139|I3L139_HUMAN" 3 1550.8751 0.33 101813 14838 4 1550.875539 388.7261 Ketosamine-3-kinase OS=Homo sapiens OX=9606 GN=FN3KRP PE=1 SV=2 6.75 2597.4 - 1.11E+06 - - - 0.2566 - 2.526 0.259 - 304.4 1 2 0 0.0004 14 0 0 0 3.69E+06 1.13E+07 - - - 1.8175 1 221125_WJC_METTL3_EV_vs_WT_F07.14839.14839.4 5.42E-06 13/90 R.FHMDSETHDPIDLQTK[136.11].E "sp|Q9Y2L1|RRP44_HUMAN,tr|G3V1J5|G3V1J5_HUMAN" 2 1920.8767 1.72 101814 14839 4 1920.87919 481.2265 Exosome complex exonuclease RRP44 OS=Homo sapiens OX=9606 GN=DIS3 PE=1 SV=2 4.64 2597.4 - 956017 - - - 1.2822 - 2.118 0.533 - 131 1 2 0 0.0025 16 0 0 0 1.88E+07 1.09E+07 - - - 4.1289 0.9991 221125_WJC_METTL3_EV_vs_WT_F07.14840.14840.4 0.00241 13/60 K.IWHHTFYNELR[166.11].V "sp|Q6S8J3|POTEE_HUMAN,sp|P63261|ACTG_HUMAN,sp|P68133|ACTS_HUMAN,sp|Q9BYX7|ACTBM_HUMAN,sp|P68032|ACTC_HUMAN,sp|P60709|ACTB_HUMAN,sp|A5A3E0|POTEF_HUMAN,sp|P0CG38|POTEI_HUMAN,sp|P0CG39|POTEJ_HUMAN,tr|A0A804GS07|A0A804GS07_HUMAN,tr|I3L3I0|I3L3I0_HUMAN,tr|G5E9R0|G5E9R0_HUMAN,tr|E7EVS6|E7EVS6_HUMAN,tr|A0A6Q8PFE4|A0A6Q8PFE4_HUMAN,tr|J3KT65|J3KT65_HUMAN,tr|I3L3R2|I3L3R2_HUMAN,tr|K7EM38|K7EM38_HUMAN,tr|A0A6Q8PH58|A0A6Q8PH58_HUMAN,tr|I3L1U9|I3L1U9_HUMAN,tr|A0A804HKV3|A0A804HKV3_HUMAN,tr|A0A2R8Y793|A0A2R8Y793_HUMAN,tr|I3L4N8|I3L4N8_HUMAN,tr|C9JUM1|C9JUM1_HUMAN,tr|C9JZR7|C9JZR7_HUMAN,tr|A0A2R8YGF8|A0A2R8YGF8_HUMAN,tr|A6NL76|A6NL76_HUMAN" 26 1524.7502 0.04 101815 14840 4 1524.749722 382.1948 POTE ankyrin domain family member E OS=Homo sapiens OX=9606 GN=POTEE PE=2 SV=3 6.92 2597.6 - 900714 - - - -0.282 - 2.157 0.297 - 127.9 1 2 0 -0.0004 11 0 0 0 4.78E+05 1.12E+07 - - - 2.1086 1 221125_WJC_METTL3_EV_vs_WT_F07.14841.14841.3 2.06E-12 21/84 K.TEGDEEAEEEQEENLEASGDYK.Y sp|P12956|XRCC6_HUMAN 1 2499.9885 1.33 101816 14841 3 2499.992431 834.3368 X-ray repair cross-complementing protein 6 OS=Homo sapiens OX=9606 GN=XRCC6 PE=1 SV=2 3.55 2597.7 - 662530 - - - 1.5676 - 3.89 0.765 - 687.1 1 2 0 0.0039 22 0 0 0 1.91E+07 1.43E+07 - - - 10.2885 1 221125_WJC_METTL3_EV_vs_WT_F07.14842.14842.3 2.61E-10 15/68 R.VK[136.11]LESPTVSTLTPSSPGK[136.11].L "sp|Q96C36|P5CR2_HUMAN,tr|A0A087WZR9|A0A087WZR9_HUMAN,tr|A0A087WTV6|A0A087WTV6_HUMAN" 3 1843.0273 0.82 101817 14842 3 1843.02811 615.3497 Pyrroline-5-carboxylate reductase 2 OS=Homo sapiens OX=9606 GN=PYCR2 PE=1 SV=1 8.56 2597.8 - 554226 - - - 0.4156 - 3.079 0.612 - 239.7 1 2 1 0.0008 18 0 0 0 4.40E+07 5.38E+07 - - - 8.1634 0.9978 221125_WJC_METTL3_EV_vs_WT_F07.14844.14844.3 0.117 16/52 K.LGAQLADLHLDNKK.L "sp|Q9HA64|KT3K_HUMAN,tr|I3L2G3|I3L2G3_HUMAN,tr|I3L139|I3L139_HUMAN" 3 1534.8467 0.29 101819 14844 3 1534.846059 512.6229 Ketosamine-3-kinase OS=Homo sapiens OX=9606 GN=FN3KRP PE=1 SV=2 6.75 2598.1 - 430074 - - - -0.4443 - 1.942 0.222 - 248.7 1 2 0 -0.0007 14 0 0 0 4.08E+06 1.43E+07 - - - 2.7787 0.9996 221125_WJC_METTL3_EV_vs_WT_F07.14847.14847.4 0.00214 13/78 K.LGAQLADLHLDNKK.L "sp|Q9HA64|KT3K_HUMAN,tr|I3L2G3|I3L2G3_HUMAN,tr|I3L139|I3L139_HUMAN" 3 1534.8467 0.33 101822 14847 4 1534.848701 384.719 Ketosamine-3-kinase OS=Homo sapiens OX=9606 GN=FN3KRP PE=1 SV=2 6.75 2598.5 - 383006 - - - 1.277 - 1.945 0.34 - 108.4 1 2 0 0.002 14 0 0 0 3.69E+06 1.12E+07 - - - 2.4269 0.8523 221125_WJC_METTL3_EV_vs_WT_F07.14850.14850.3 0.000388 19/80 R.LPLSTPSPGNGSQGSHPLVSR.T sp|Q6ZU65|UBN2_HUMAN 1 2087.076 -1 101823 14850 3 2088.06127 696.6993 Ubinuclein-2 OS=Homo sapiens OX=9606 GN=UBN2 PE=1 SV=2 9.76 2598.9 - 371182 - - - 472.0978 - 2.747 0.477 - 235.8 1 2 0 0.9853 21 0 0 0 0.00E+00 0.00E+00 - - - 6.0078 1 221125_WJC_METTL3_EV_vs_WT_F07.14851.14851.3 3.76E-09 Nov-80 R.SMMQDR[166.11]EDQSILC[160.03]TGESGAGK[136.11].T "sp|P35579|MYH9_HUMAN,tr|Q5BKV1|Q5BKV1_HUMAN" 2 2317.0104 0.92 101824 14851 3 2317.004796 773.3441 Myosin-9 OS=Homo sapiens OX=9606 GN=MYH9 PE=1 SV=4 4.32 2599 - 736386 - - - -2.3975 - 2.772 0.693 - 152.1 1 2 1 -0.0056 21 0 0 0 1.04E+07 1.13E+07 - - - 8.7091 1 221125_WJC_METTL3_EV_vs_WT_F07.14854.14854.3 2.60E-12 19/80 R.SMMQDREDQSILC[160.03]TGESGAGK.T "sp|P35579|MYH9_HUMAN,tr|Q5BKV1|Q5BKV1_HUMAN" 2 2298.9879 0.92 101827 14854 3 2298.985178 767.3366 Myosin-9 OS=Homo sapiens OX=9606 GN=MYH9 PE=1 SV=4 4.32 2599.4 - 551786 - - - -1.1757 - 3.531 0.764 - 501.4 1 2 1 -0.0027 21 0 0 0 1.04E+07 1.13E+07 - - - 10.0817 1 221125_WJC_METTL3_EV_vs_WT_F07.14861.14861.3 1.25E-10 21/64 R.AQVQEFC[160.03]DYGTK[136.11]EEC[160.03]MK[136.11].A "sp|Q86U44|MTA70_HUMAN,tr|H0YFV6|H0YFV6_HUMAN" 2 2137.909 0.04 101832 14861 3 2137.907428 713.6436 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 4.41 2600.1 - 692093 - - - -0.718 - 4.139 0.727 - 445.6 1 2 1 -0.0015 17 0 0 0 3.95E+05 1.11E+07 - - - 10.2334 0.9996 221125_WJC_METTL3_EV_vs_WT_F07.14863.14863.3 2.06E-05 Dec-68 R.SPLLAGGSPPQPVVPAHK.D "sp|Q8NFH5|NUP35_HUMAN,tr|F8WCF5|F8WCF5_HUMAN,tr|F8WEL4|F8WEL4_HUMAN,tr|C9JIY9|C9JIY9_HUMAN,tr|C9IYQ7|C9IYQ7_HUMAN" 5 1750.973 1.08 101834 14863 3 1750.978808 584.6649 Nucleoporin NUP35 OS=Homo sapiens OX=9606 GN=NUP35 PE=1 SV=1 8.49 2600.4 - 273245 - - - 3.3147 - 2.405 0.413 - 158.3 1 2 0 0.0058 18 0 0 0 6.91E+06 6.37E+06 - - - 5.3281 1 221125_WJC_METTL3_EV_vs_WT_F07.14867.14867.3 8.90E-06 15/56 K.THINIVVIGHVDSGK[136.11].S "sp|Q05639|EF1A2_HUMAN,sp|P68104|EF1A1_HUMAN,sp|Q5VTE0|EF1A3_HUMAN,tr|A0A2R8Y488|A0A2R8Y488_HUMAN,tr|A0A2R8YDN5|A0A2R8YDN5_HUMAN,tr|A0A7I2V659|A0A7I2V659_HUMAN,tr|A0A7I2V3H3|A0A7I2V3H3_HUMAN,tr|Q5JR01|Q5JR01_HUMAN,tr|A0A2U3TZH3|A0A2U3TZH3_HUMAN,tr|A0A7I2V5N4|A0A7I2V5N4_HUMAN,tr|A0A087WVQ9|A0A087WVQ9_HUMAN,tr|A6PW80|A6PW80_HUMAN,tr|A0A087WV01|A0A087WV01_HUMAN,tr|A0A2R8Y660|A0A2R8Y660_HUMAN,tr|A0A6Q8PFK6|A0A6Q8PFK6_HUMAN" 15 1595.8875 0.38 101836 14867 3 1595.886035 532.9698 Elongation factor 1-alpha 2 OS=Homo sapiens OX=9606 GN=EEF1A2 PE=1 SV=1 6.61 2601 - 3.34E+07 - - - -0.9117 - 3.288 0.566 - 361.1 1 2 0 -0.0015 15 0 0 0 4.92E+08 1.30E+09 - - - 7.9558 0.9999 221125_WJC_METTL3_EV_vs_WT_F07.14868.14868.3 0.0107 Dec-40 K.IWHHTFYNELR[166.11].V "sp|Q6S8J3|POTEE_HUMAN,sp|P63261|ACTG_HUMAN,sp|P68133|ACTS_HUMAN,sp|Q9BYX7|ACTBM_HUMAN,sp|P68032|ACTC_HUMAN,sp|P60709|ACTB_HUMAN,sp|A5A3E0|POTEF_HUMAN,sp|P0CG38|POTEI_HUMAN,sp|P0CG39|POTEJ_HUMAN,tr|A0A804GS07|A0A804GS07_HUMAN,tr|I3L3I0|I3L3I0_HUMAN,tr|G5E9R0|G5E9R0_HUMAN,tr|E7EVS6|E7EVS6_HUMAN,tr|A0A6Q8PFE4|A0A6Q8PFE4_HUMAN,tr|J3KT65|J3KT65_HUMAN,tr|I3L3R2|I3L3R2_HUMAN,tr|K7EM38|K7EM38_HUMAN,tr|A0A6Q8PH58|A0A6Q8PH58_HUMAN,tr|I3L1U9|I3L1U9_HUMAN,tr|A0A804HKV3|A0A804HKV3_HUMAN,tr|A0A2R8Y793|A0A2R8Y793_HUMAN,tr|I3L4N8|I3L4N8_HUMAN,tr|C9JUM1|C9JUM1_HUMAN,tr|C9JZR7|C9JZR7_HUMAN,tr|A0A2R8YGF8|A0A2R8YGF8_HUMAN,tr|A6NL76|A6NL76_HUMAN" 26 1524.7502 0.95 101837 14868 3 1524.748276 509.2573 POTE ankyrin domain family member E OS=Homo sapiens OX=9606 GN=POTEE PE=2 SV=3 6.92 2601 - 2.13E+06 - - - -1.2304 - 2.247 0.368 - 266.9 1 2 0 -0.0019 11 0 0 0 4.12E+07 4.35E+07 - - - 4.9422 1 221125_WJC_METTL3_EV_vs_WT_F07.14871.14871.2 0.00319 14/28 K.THINIVVIGHVDSGK.S "sp|Q05639|EF1A2_HUMAN,sp|P68104|EF1A1_HUMAN,sp|Q5VTE0|EF1A3_HUMAN,tr|A0A2R8Y488|A0A2R8Y488_HUMAN,tr|A0A2R8YDN5|A0A2R8YDN5_HUMAN,tr|A0A7I2V659|A0A7I2V659_HUMAN,tr|A0A7I2V3H3|A0A7I2V3H3_HUMAN,tr|Q5JR01|Q5JR01_HUMAN,tr|A0A2U3TZH3|A0A2U3TZH3_HUMAN,tr|A0A7I2V5N4|A0A7I2V5N4_HUMAN,tr|A0A087WVQ9|A0A087WVQ9_HUMAN,tr|A6PW80|A6PW80_HUMAN,tr|A0A087WV01|A0A087WV01_HUMAN,tr|A0A2R8Y660|A0A2R8Y660_HUMAN,tr|A0A6Q8PFK6|A0A6Q8PFK6_HUMAN" 15 1587.8733 0.28 101840 14871 2 1587.872229 794.9439 Elongation factor 1-alpha 2 OS=Homo sapiens OX=9606 GN=EEF1A2 PE=1 SV=1 6.61 2601.4 - 253456 - - - -0.6682 - 3.159 0.543 - 480.7 1 2 0 -0.0011 15 0 0 0 8.68E+06 3.10E+07 - - - 5.8792 1 221125_WJC_METTL3_EV_vs_WT_F07.14872.14872.2 2.36E-07 30-Nov K.QGAENMIQTYSNGSTK.D "sp|Q16512|PKN1_HUMAN,tr|K7EKY9|K7EKY9_HUMAN,tr|K7EM57|K7EM57_HUMAN" 3 1727.7785 4.13 101841 14872 2 1727.775004 864.8965 Serine\threonine-protein kinase N1 OS=Homo sapiens OX=9606 GN=PKN1 PE=1 SV=2 6 2601.5 - 153422 - - - -2.002 - 2.313 0.627 - 417 1 2 0 -0.0035 16 0 0 0 4.02E+06 9.73E+05 - - - 5.7325 1 221125_WJC_METTL3_EV_vs_WT_F07.14877.14877.3 1.49E-06 16/56 R.VLSAPPHFHFGQTNR[166.11].T sp|P26641|EF1G_HUMAN 1 1716.8724 1.12 101844 14877 3 1716.875338 573.2981 Elongation factor 1-gamma OS=Homo sapiens OX=9606 GN=EEF1G PE=1 SV=3 9.73 2602.1 - 3.00E+06 - - - 1.7153 - 2.715 0.549 - 386 1 2 0 0.0029 15 0 0 0 1.36E+08 1.21E+08 - - - 7.2662 1 221125_WJC_METTL3_EV_vs_WT_F07.14881.14881.3 1.68E-08 13/64 R.VNAQDNELSNVEFHC[160.03]GR.A "sp|Q8IZ69|TRM2A_HUMAN,tr|F2Z2W7|F2Z2W7_HUMAN,tr|H7C100|H7C100_HUMAN" 3 1987.8806 0.05 101848 14881 3 1987.881923 663.6342 tRNA (uracil-5-)-methyltransferase homolog A OS=Homo sapiens OX=9606 GN=TRMT2A PE=1 SV=2 4.65 2602.5 - 444980 - - - 0.6469 - 2.945 0.613 - 208.3 1 2 0 0.0013 17 0 0 0 6.03E+06 1.11E+08 - - - 8.1027 1 221125_WJC_METTL3_EV_vs_WT_F07.14886.14886.3 8.63E-05 15/52 K.TIDLGAAAHYTGDK.A sp|Q14677|EPN4_HUMAN 1 1431.6994 1.91 101851 14886 3 1431.701022 478.2404 Clathrin interactor 1 OS=Homo sapiens OX=9606 GN=CLINT1 PE=1 SV=1 5.18 2603.2 - 900250 - - - 1.1273 - 2.831 0.513 - 191.7 1 2 0 0.0016 14 0 0 0 1.57E+07 8.19E+06 - - - 7.0245 1 221125_WJC_METTL3_EV_vs_WT_F07.14889.14889.2 6.77E-09 18/30 R.QSSGENC[160.03]DVVVNTLGK.R sp|P01833|PIGR_HUMAN 1 1705.7941 999 101854 14889 2 1705.794563 853.9043 Polymeric immunoglobulin receptor OS=Homo sapiens OX=9606 GN=PIGR PE=1 SV=4 4.37 2603.6 - 714081 - - - 0.2632 - 3.626 0.708 - 1153.8 1 2 0 0.0004 16 0 0 0 1.48E+07 0.00E+00 - - - 7.4371 1 221125_WJC_METTL3_EV_vs_WT_F07.14890.14890.3 1.03E-08 20/76 K.K[136.11]PSAAPEAGASALPNPPALK[136.11].K "sp|P39880|CUX1_HUMAN,tr|A0A2R8Y852|A0A2R8Y852_HUMAN,tr|A0A2R8YDI1|A0A2R8YDI1_HUMAN" 3 1902.0546 2.07 101855 14890 3 1902.054623 635.0255 Homeobox protein cut-like 1 OS=Homo sapiens OX=9606 GN=CUX1 PE=1 SV=3 8.59 2603.7 - 589528 - - - 0.0321 - 3.525 0.592 - 400.7 1 2 0 0.0001 20 0 0 0 1.75E+07 8.47E+06 - - - 8.1967 0.9988 221125_WJC_METTL3_EV_vs_WT_F07.14891.14891.3 4.02E-09 15/88 F.SSVQATQLQTTQSVEGATGSAVK.S "sp|Q14157|UBP2L_HUMAN,tr|F8W726|F8W726_HUMAN" 2 2277.1448 3.01 101856 14891 3 2277.143619 760.0556 Ubiquitin-associated protein 2-like OS=Homo sapiens OX=9606 GN=UBAP2L PE=1 SV=2 5.72 2603.8 - 585533 - - - -0.5336 - 3.673 0.577 - 216 1 1 0 -0.0012 23 0 0 0 5.19E+06 1.72E+06 - - - 8.0247 1 221125_WJC_METTL3_EV_vs_WT_F07.14897.14897.3 2.57E-09 18/60 K.NQVAMNPTNTVFDAK[136.11]R[166.11].L "sp|P11142|HSP7C_HUMAN,tr|E9PQQ4|E9PQQ4_HUMAN,tr|E9PNE6|E9PNE6_HUMAN,tr|E9PKE3|E9PKE3_HUMAN,tr|E9PLF4|E9PLF4_HUMAN,tr|E9PK54|E9PK54_HUMAN,tr|E9PN25|E9PN25_HUMAN,tr|E9PPY6|E9PPY6_HUMAN,tr|E9PQK7|E9PQK7_HUMAN" 9 1822.9115 0.13 101860 14897 3 1822.912377 608.6444 Heat shock cognate 71 kDa protein OS=Homo sapiens OX=9606 GN=HSPA8 PE=1 SV=1 8.75 2604.6 - 4.34E+06 - - - 0.4882 - 3.262 0.616 - 511.8 1 2 0 0.0009 16 0 0 0 2.44E+07 1.93E+08 - - - 8.4413 0.9994 221125_WJC_METTL3_EV_vs_WT_F07.14898.14898.3 0.000415 Nov-40 K.IRLENEIQTYR.S "sp|P13645|K1C10_HUMAN,tr|A0A1B0GVI3|A0A1B0GVI3_HUMAN" 2 1433.7627 999 101861 14898 3 1433.762855 478.9282 "Keratin, type I cytoskeletal 10 OS=Homo sapiens OX=9606 GN=KRT10 PE=1 SV=6" 6.14 2604.7 - 1.43E+06 - - - 0.1241 - 2.052 0.388 - 256.1 1 2 1 0.0002 11 0 0 0 5.72E+07 0.00E+00 - - - 4.9078 1 221125_WJC_METTL3_EV_vs_WT_F07.14901.14901.2 0.000257 18/28 K.THINIVVIGHVDSGK[136.11].S "sp|Q05639|EF1A2_HUMAN,sp|P68104|EF1A1_HUMAN,sp|Q5VTE0|EF1A3_HUMAN,tr|A0A2R8Y488|A0A2R8Y488_HUMAN,tr|A0A2R8YDN5|A0A2R8YDN5_HUMAN,tr|A0A7I2V659|A0A7I2V659_HUMAN,tr|A0A7I2V3H3|A0A7I2V3H3_HUMAN,tr|Q5JR01|Q5JR01_HUMAN,tr|A0A2U3TZH3|A0A2U3TZH3_HUMAN,tr|A0A7I2V5N4|A0A7I2V5N4_HUMAN,tr|A0A087WVQ9|A0A087WVQ9_HUMAN,tr|A6PW80|A6PW80_HUMAN,tr|A0A087WV01|A0A087WV01_HUMAN,tr|A0A2R8Y660|A0A2R8Y660_HUMAN,tr|A0A6Q8PFK6|A0A6Q8PFK6_HUMAN" 15 1595.8875 0.28 101864 14901 2 1595.886823 798.951 Elongation factor 1-alpha 2 OS=Homo sapiens OX=9606 GN=EEF1A2 PE=1 SV=1 6.61 2605 - 780346 - - - -0.4179 - 3.609 0.679 - 856.9 1 2 0 -0.0007 15 0 0 0 8.68E+06 3.07E+07 - - - 7.2113 1 221125_WJC_METTL3_EV_vs_WT_F07.14903.14903.3 6.04E-09 14/84 K.TEGDEEAEEEQEENLEASGDYK[136.11].Y sp|P12956|XRCC6_HUMAN 1 2508.0027 1.33 101866 14903 3 2508.002085 837.0082 X-ray repair cross-complementing protein 6 OS=Homo sapiens OX=9606 GN=XRCC6 PE=1 SV=2 3.55 2605.3 - 471249 - - - -0.25 - 2.935 0.755 - 214.2 1 2 0 -0.0006 22 0 0 0 1.91E+07 1.43E+07 - - - 9.51 1 221125_WJC_METTL3_EV_vs_WT_F07.14904.14904.3 3.26E-07 19/48 R.GISHVIVDEIHER.D sp|Q08211|DHX9_HUMAN 1 1502.7841 1.01 101867 14904 3 1502.785597 501.9353 ATP-dependent RNA helicase A OS=Homo sapiens OX=9606 GN=DHX9 PE=1 SV=4 5.27 2605.4 - 463337 - - - 0.9689 - 3.283 0.525 - 541.6 1 2 0 0.0015 13 0 0 0 3.61E+07 3.58E+07 - - - 7.6159 0.9996 221125_WJC_METTL3_EV_vs_WT_F07.14905.14905.3 0.00184 Nov-76 K.GGDPLEK[136.11]QDQISGLSQSEVK[136.11].T "sp|Q99590|SCAFB_HUMAN,tr|F8VXG7|F8VXG7_HUMAN,tr|A0A0A0MTP7|A0A0A0MTP7_HUMAN" 3 2130.0775 5.54 101868 14905 3 2130.078464 711.0331 Protein SCAF11 OS=Homo sapiens OX=9606 GN=SCAF11 PE=1 SV=2 4.32 2605.6 - 271405 - - - 0.4328 - 2.45 0.404 - 91.9 1 2 1 0.0009 20 0 0 0 2.48E+07 4.47E+06 - - - 5.2179 1 221125_WJC_METTL3_EV_vs_WT_F07.14906.14906.2 4.85E-09 Dec-42 R.VTLLTPAGATGSGGGTSGDSSK[136.11].G sp|Q9BZI7|REN3B_HUMAN 1 1927.9578 1.39 101869 14906 2 1927.96187 964.9862 Regulator of nonsense transcripts 3B OS=Homo sapiens OX=9606 GN=UPF3B PE=1 SV=1 5.81 2605.7 - 168086 - - - 2.1038 - 2.643 0.658 - 263.2 1 2 0 0.0041 22 0 0 0 5.00E+06 3.60E+06 - - - 6.2892 1 221125_WJC_METTL3_EV_vs_WT_F07.14910.14910.3 2.37E-05 22/48 R.GISHVIVDEIHER[166.11].D sp|Q08211|DHX9_HUMAN 1 1512.7924 1.03 101872 14910 3 1512.793055 505.2714 ATP-dependent RNA helicase A OS=Homo sapiens OX=9606 GN=DHX9 PE=1 SV=4 5.27 2606.1 - 1.06E+06 - - - 0.4257 - 3.609 0.53 - 851.7 1 2 0 0.0006 13 0 0 0 3.59E+07 3.49E+07 - - - 7.9286 1 221125_WJC_METTL3_EV_vs_WT_F07.14911.14911.3 1.08E-06 19/60 K.NQVAMNPTNTVFDAKR.L "sp|P11142|HSP7C_HUMAN,tr|E9PQQ4|E9PQQ4_HUMAN,tr|E9PNE6|E9PNE6_HUMAN,tr|E9PKE3|E9PKE3_HUMAN,tr|E9PLF4|E9PLF4_HUMAN,tr|E9PK54|E9PK54_HUMAN,tr|E9PN25|E9PN25_HUMAN,tr|E9PPY6|E9PPY6_HUMAN,tr|E9PQK7|E9PQK7_HUMAN" 9 1804.889 0.13 101873 14911 3 1804.892158 602.6369 Heat shock cognate 71 kDa protein OS=Homo sapiens OX=9606 GN=HSPA8 PE=1 SV=1 8.75 2606.3 - 734850 - - - 1.7403 - 3.636 0.611 - 579.6 1 2 0 0.0031 16 0 0 0 2.44E+07 1.93E+08 - - - 8.6634 1 221125_WJC_METTL3_EV_vs_WT_F07.14914.14914.3 6.13E-08 17/68 K.SGVYQHVTGEMMGGHAIR[166.11].L "sp|P07858|CATB_HUMAN,tr|A0A7I2V4Z9|A0A7I2V4Z9_HUMAN,tr|A0A7I2V440|A0A7I2V440_HUMAN,tr|R4GMQ5|R4GMQ5_HUMAN,tr|E9PSG5|E9PSG5_HUMAN,tr|A0A7I2V668|A0A7I2V668_HUMAN,tr|A0A7I2YQK9|A0A7I2YQK9_HUMAN,tr|E9PHZ5|E9PHZ5_HUMAN,tr|A0A7I2V367|A0A7I2V367_HUMAN" 9 1938.9068 1.12 101876 14914 3 1938.911089 647.3095 Cathepsin B OS=Homo sapiens OX=9606 GN=CTSB PE=1 SV=3 6.66 2606.6 - 176876 - - - 2.209 - 3.237 0.685 - 349.4 1 2 0 0.0043 18 0 0 0 2.60E+06 2.32E+06 - - - 9.1009 1 221125_WJC_METTL3_EV_vs_WT_F07.14916.14916.3 1.18E-07 14/56 K.KAEAGAGSATEFQFR.G "sp|Q9NQ39|RS10L_HUMAN,sp|P46783|RS10_HUMAN" 2 1568.7583 1.25 101877 14916 3 1568.761434 523.9267 Putative 40S ribosomal protein S10-like OS=Homo sapiens OX=9606 GN=RPS10P5 PE=5 SV=1 6.14 2606.9 - 318699 - - - 1.985 - 2.493 0.564 - 236.6 1 2 0 0.0031 15 0 0 0 1.35E+07 1.08E+07 - - - 7.2108 0.9927 221125_WJC_METTL3_EV_vs_WT_F07.14918.14918.2 2.78E-05 16-Oct V.VIGHVDSGK[136.11].S "sp|Q05639|EF1A2_HUMAN,sp|P68104|EF1A1_HUMAN,sp|Q5VTE0|EF1A3_HUMAN,tr|A0A2R8Y488|A0A2R8Y488_HUMAN,tr|A0A2R8YDN5|A0A2R8YDN5_HUMAN,tr|A0A7I2V659|A0A7I2V659_HUMAN,tr|A0A7I2V3H3|A0A7I2V3H3_HUMAN,tr|Q5JR01|Q5JR01_HUMAN,tr|A0A2U3TZH3|A0A2U3TZH3_HUMAN,tr|A0A7I2V5N4|A0A7I2V5N4_HUMAN,tr|A0A087WVQ9|A0A087WVQ9_HUMAN,tr|A6PW80|A6PW80_HUMAN,tr|A0A087WV01|A0A087WV01_HUMAN,tr|A0A2R8Y660|A0A2R8Y660_HUMAN,tr|A0A6Q8PFK6|A0A6Q8PFK6_HUMAN" 15 918.5014 0.39 101878 14918 2 918.501366 460.258 Elongation factor 1-alpha 2 OS=Homo sapiens OX=9606 GN=EEF1A2 PE=1 SV=1 6.71 2607.1 - 6.14E+06 - - - -0.0697 - 2.021 0.508 - 274.3 1 1 0 -0.0001 9 0 0 0 6.60E+07 1.70E+08 - - - 4.8286 0.9383 221125_WJC_METTL3_EV_vs_WT_F07.14919.14919.4 0.0585 12/114 K.QLVAR[166.11]PDVVEMHDVTAQDPK[136.11].L "sp|Q13435|SF3B2_HUMAN,tr|E9PPJ0|E9PPJ0_HUMAN" 2 2265.1542 1.14 101879 14919 4 2265.156671 567.2958 Splicing factor 3B subunit 2 OS=Homo sapiens OX=9606 GN=SF3B2 PE=1 SV=2 4.66 2607.1 - 3.37E+06 - - - 1.075 - 1.561 0.135 - 42.9 1 2 0 0.0024 20 0 0 0 1.19E+08 1.05E+08 - - - 0.5492 1 221125_WJC_METTL3_EV_vs_WT_F07.14921.14921.3 6.23E-09 14/68 R.EQLSSANHSLQLASQIQK[136.11].A "sp|Q13948|CASP_HUMAN,sp|P39880|CUX1_HUMAN,tr|A0A2R8Y852|A0A2R8Y852_HUMAN,tr|A0A2R8YDI1|A0A2R8YDI1_HUMAN" 4 1989.0371 1.46 101881 14921 3 1989.037295 664.0196 Protein CASP OS=Homo sapiens OX=9606 GN=CUX1 PE=1 SV=2 6.85 2607.3 - 1.02E+06 - - - 0.1141 - 3.125 0.585 - 203 1 2 0 0.0002 18 0 0 0 1.90E+08 1.30E+08 - - - 7.8994 1 221125_WJC_METTL3_EV_vs_WT_F07.14922.14922.3 1.89E-08 17/68 R.EQLSSANHSLQLASQIQK.A "sp|Q13948|CASP_HUMAN,sp|P39880|CUX1_HUMAN,tr|A0A2R8Y852|A0A2R8Y852_HUMAN,tr|A0A2R8YDI1|A0A2R8YDI1_HUMAN" 4 1981.0229 1.46 101882 14922 3 1981.023748 661.3482 Protein CASP OS=Homo sapiens OX=9606 GN=CUX1 PE=1 SV=2 6.85 2607.4 - 913565 - - - 0.4442 - 3.13 0.55 - 357.3 1 2 0 0.0009 18 0 0 0 1.90E+08 1.30E+08 - - - 7.513 1 221125_WJC_METTL3_EV_vs_WT_F07.14925.14925.2 0.00124 13/30 L.AQDQTQDTQLITVDEK.L "sp|O43181|NDUS4_HUMAN,tr|D6RI09|D6RI09_HUMAN,tr|H0Y9M8|H0Y9M8_HUMAN,tr|D6R916|D6R916_HUMAN" 4 1831.88 1.53 101885 14925 2 1831.880762 916.9473 "NADH dehydrogenase [ubiquinone] iron-sulfur protein 4, mitochondrial OS=Homo sapiens OX=9606 GN=NDUFS4 PE=1 SV=1" 3.84 2607.8 - 263625 - - - 0.4422 - 3.084 0.62 - 492.5 1 1 0 0.0008 16 0 0 0 4.09E+06 2.68E+06 - - - 6.3889 1 221125_WJC_METTL3_EV_vs_WT_F07.14926.14926.2 9.02E-07 14/30 L.AQDQTQDTQLITVDEK[136.11].L "sp|O43181|NDUS4_HUMAN,tr|D6RI09|D6RI09_HUMAN,tr|H0Y9M8|H0Y9M8_HUMAN,tr|D6R916|D6R916_HUMAN" 4 1839.8942 1.53 101886 14926 2 1839.895399 920.9544 "NADH dehydrogenase [ubiquinone] iron-sulfur protein 4, mitochondrial OS=Homo sapiens OX=9606 GN=NDUFS4 PE=1 SV=1" 3.84 2607.9 - 211825 - - - 0.6778 - 3.021 0.665 - 518.1 1 1 0 0.0012 16 0 0 0 4.09E+06 2.68E+06 - - - 6.6704 1 221125_WJC_METTL3_EV_vs_WT_F07.14928.14928.2 1.12E-06 Nov-42 R.VTLLTPAGATGSGGGTSGDSSK.G sp|Q9BZI7|REN3B_HUMAN 1 1919.9436 1.39 101888 14928 2 1919.941107 960.9791 Regulator of nonsense transcripts 3B OS=Homo sapiens OX=9606 GN=UPF3B PE=1 SV=1 5.81 2608.2 - 165517 - - - -1.3058 - 2.613 0.614 - 163.7 1 2 0 -0.0025 22 0 0 0 5.00E+06 3.60E+06 - - - 5.9366 1 221125_WJC_METTL3_EV_vs_WT_F07.14931.14931.3 1.54E-13 28/76 K.QLVARPDVVEMHDVTAQDPK.L "sp|Q13435|SF3B2_HUMAN,tr|E9PPJ0|E9PPJ0_HUMAN" 2 2247.1318 1.12 101889 14931 3 2247.133796 750.0512 Splicing factor 3B subunit 2 OS=Homo sapiens OX=9606 GN=SF3B2 PE=1 SV=2 4.66 2608.6 - 1.16E+06 - - - 0.9034 - 4.598 0.701 - 599 1 2 0 0.002 20 0 0 0 3.16E+07 2.84E+07 - - - 10.0561 1 221125_WJC_METTL3_EV_vs_WT_F07.14933.14933.3 5.95E-13 23/76 K.QLVAR[166.11]PDVVEMHDVTAQDPK[136.11].L "sp|Q13435|SF3B2_HUMAN,tr|E9PPJ0|E9PPJ0_HUMAN" 2 2265.1542 1.12 101891 14933 3 2265.154019 756.0587 Splicing factor 3B subunit 2 OS=Homo sapiens OX=9606 GN=SF3B2 PE=1 SV=2 4.66 2608.8 - 1.31E+06 - - - -0.0958 - 3.795 0.669 - 349.6 1 2 0 -0.0002 20 0 0 0 3.16E+07 2.84E+07 - - - 9.2342 0.9693 221125_WJC_METTL3_EV_vs_WT_F07.14936.14936.2 0.0044 14-Aug V.IGHVDSGK.S "sp|Q05639|EF1A2_HUMAN,sp|P68104|EF1A1_HUMAN,sp|Q5VTE0|EF1A3_HUMAN,tr|A0A2R8Y488|A0A2R8Y488_HUMAN,tr|A0A2R8YDN5|A0A2R8YDN5_HUMAN,tr|A0A7I2V659|A0A7I2V659_HUMAN,tr|A0A7I2V3H3|A0A7I2V3H3_HUMAN,tr|Q5JR01|Q5JR01_HUMAN,tr|A0A2U3TZH3|A0A2U3TZH3_HUMAN,tr|A0A7I2V5N4|A0A7I2V5N4_HUMAN,tr|A0A087WVQ9|A0A087WVQ9_HUMAN,tr|A6PW80|A6PW80_HUMAN,tr|A0A087WV01|A0A087WV01_HUMAN,tr|A0A2R8Y660|A0A2R8Y660_HUMAN,tr|A0A6Q8PFK6|A0A6Q8PFK6_HUMAN" 15 811.4188 0.39 101894 14936 2 811.419255 406.7167 Elongation factor 1-alpha 2 OS=Homo sapiens OX=9606 GN=EEF1A2 PE=1 SV=1 6.74 2609.1 - 457585 - - - 0.5398 - 1.414 0.404 - 204.3 1 1 0 0.0004 8 0 0 0 1.38E+07 3.54E+07 - - - 3.0696 1 221125_WJC_METTL3_EV_vs_WT_F07.14939.14939.2 7.65E-15 18/36 R.TYGGEEDVLGDESQTTPNR.G sp|Q9UMR3|TBX20_HUMAN 1 2066.9029 2.43 101897 14939 2 2066.898772 1034.4587 T-box transcription factor TBX20 OS=Homo sapiens OX=9606 GN=TBX20 PE=1 SV=4 3.83 2609.5 - 234337 - - - -1.9836 - 3.541 0.636 - 693.8 1 2 0 -0.0041 19 0 0 0 4.94E+06 2.03E+06 - - - 6.8458 1 221125_WJC_METTL3_EV_vs_WT_F07.14942.14942.3 2.40E-07 19/88 R.IRPLEVPTTAGPASASTPTDGAK.K "sp|Q9ULL5|PRR12_HUMAN,tr|A0A3Q5ADB5|A0A3Q5ADB5_HUMAN" 2 2236.1699 2.14 101898 14942 3 2236.168926 746.3973 Proline-rich protein 12 OS=Homo sapiens OX=9606 GN=PRR12 PE=1 SV=3 6.07 2609.9 - 697636 - - - -0.4472 - 3.67 0.552 - 398.3 1 2 0 -0.001 23 0 0 0 2.31E+07 1.08E+07 - - - 7.7442 1 221125_WJC_METTL3_EV_vs_WT_F07.14944.14944.3 4.03E-08 16/60 K.FQEHIIQAPK[136.11]PVEAIK[136.11].R "sp|Q9UHD1|CHRD1_HUMAN,tr|E9PSD5|E9PSD5_HUMAN,tr|E9PIZ4|E9PIZ4_HUMAN,tr|E9PPQ5|E9PPQ5_HUMAN" 4 1863.0589 0.84 101900 14944 3 1863.058189 622.0269 Cysteine and histidine-rich domain-containing protein 1 OS=Homo sapiens OX=9606 GN=CHORDC1 PE=1 SV=2 6.76 2610.2 - 734289 - - - -0.3918 - 3.024 0.582 - 250.4 1 2 0 -0.0007 16 0 0 0 1.05E+07 1.25E+07 - - - 7.8679 0.9996 221125_WJC_METTL3_EV_vs_WT_F07.14945.14945.4 3.90E-05 15/108 K.VELKDQTKPTPLILDEQGR.T sp|O43395|PRPF3_HUMAN 1 2179.1848 2.3 101901 14945 4 2179.186932 545.8035 U4\U6 small nuclear ribonucleoprotein Prp3 OS=Homo sapiens OX=9606 GN=PRPF3 PE=1 SV=2 4.78 2610.3 - 692694 - - - 0.9563 - 2.351 0.424 - 132.2 1 2 1 0.0021 19 0 0 0 5.53E+07 2.40E+07 - - - 3.2051 0.9888 221125_WJC_METTL3_EV_vs_WT_F07.14950.14950.2 1.71E-06 24-Dec K.IELFGR[166.11]PHNVQPN.W sp|Q86U44|MTA70_HUMAN 1 1529.7978 0.001 101906 14950 2 1529.800481 765.9062 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 6.75 2610.9 - 203383 - - - 1.7323 - 2.396 0.546 - 302.4 1 1 0 0.0027 13 0 0 0 0.00E+00 1.01E+07 - - - 5.3156 1 221125_WJC_METTL3_EV_vs_WT_F07.14952.14952.3 4.05E-10 15/64 Y.VHYEIDAC[160.03]MDSEAPGSK[136.11].D "sp|Q86U44|MTA70_HUMAN,tr|H0YFV6|H0YFV6_HUMAN" 2 1915.8172 0.001 101907 14952 3 1915.820354 639.613 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 4.31 2611.2 - 306271 - - - 1.6651 - 3.171 0.654 - 276.2 1 1 0 0.0032 17 0 0 0 0.00E+00 7.52E+06 - - - 8.746 0.9999 221125_WJC_METTL3_EV_vs_WT_F07.14954.14954.4 0.00139 16/90 K.FQEHIIQAPK[136.11]PVEAIK[136.11].R "sp|Q9UHD1|CHRD1_HUMAN,tr|E9PSD5|E9PSD5_HUMAN,tr|E9PIZ4|E9PIZ4_HUMAN,tr|E9PPQ5|E9PPQ5_HUMAN" 4 1863.0589 0.39 101908 14954 4 1863.058994 466.772 Cysteine and histidine-rich domain-containing protein 1 OS=Homo sapiens OX=9606 GN=CHORDC1 PE=1 SV=2 6.76 2611.4 - 1.25E+06 - - - 0.0403 - 2.072 0.421 - 84.1 1 2 0 0.0001 16 0 0 0 7.72E+06 1.97E+07 - - - 3.147 0.8169 221125_WJC_METTL3_EV_vs_WT_F07.14957.14957.2 0.107 14-Jul K.IELFGR[166.11]PH.N sp|Q86U44|MTA70_HUMAN 1 977.5322 0.01 101911 14957 2 977.532929 489.7734 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 6.75 2611.8 - 448876 - - - 0.7253 - 1.418 0.182 - 138.5 1 1 0 0.0007 8 0 0 0 5.04E+04 5.65E+06 - - - 1.4383 1 221125_WJC_METTL3_EV_vs_WT_F07.14959.14959.2 4.78E-11 14/36 R.TYGGEEDVLGDESQTTPNR[166.11].G sp|Q9UMR3|TBX20_HUMAN 1 2076.9111 2.43 101913 14959 2 2076.902263 1039.4628 T-box transcription factor TBX20 OS=Homo sapiens OX=9606 GN=TBX20 PE=1 SV=4 3.83 2612 - 206847 - - - -4.2751 - 2.926 0.732 - 485.1 1 2 0 -0.0089 19 0 0 0 4.94E+06 2.03E+06 - - - 7.0843 0.9999 221125_WJC_METTL3_EV_vs_WT_F07.14961.14961.2 0.000199 30-Nov K.NQVAMNPTNTVFDAK[136.11]R[166.11].L "sp|P11142|HSP7C_HUMAN,tr|E9PQQ4|E9PQQ4_HUMAN,tr|E9PNE6|E9PNE6_HUMAN,tr|E9PKE3|E9PKE3_HUMAN,tr|E9PLF4|E9PLF4_HUMAN,tr|E9PK54|E9PK54_HUMAN,tr|E9PN25|E9PN25_HUMAN,tr|E9PPY6|E9PPY6_HUMAN,tr|E9PQK7|E9PQK7_HUMAN" 9 1822.9115 0.03 101915 14961 2 1822.910708 912.463 Heat shock cognate 71 kDa protein OS=Homo sapiens OX=9606 GN=HSPA8 PE=1 SV=1 8.75 2612.3 - 170161 - - - -0.4273 - 2.414 0.564 - 320.9 1 2 0 -0.0008 16 0 0 0 8.97E+04 2.85E+06 - - - 5.3731 1 221125_WJC_METTL3_EV_vs_WT_F07.14964.14964.3 1.76E-13 26/76 K.ESAC[160.03]ALSGADEQPPFHPEPR.K sp|P17509|HXB6_HUMAN 1 2193.9749 2.36 101916 14964 3 2193.977307 732.3323 Homeobox protein Hox-B6 OS=Homo sapiens OX=9606 GN=HOXB6 PE=1 SV=4 4.4 2612.7 - 2.87E+06 - - - 1.0825 - 4.201 0.713 - 646.4 1 2 0 0.0024 20 0 0 0 4.07E+07 1.72E+07 - - - 9.9707 0.9998 221125_WJC_METTL3_EV_vs_WT_F07.14966.14966.4 1.54E-06 15/108 K.VELK[136.11]DQTK[136.11]PTPLILDEQGR[166.11].T sp|O43395|PRPF3_HUMAN 1 2205.2215 2.3 101918 14966 4 2205.224762 552.3127 U4\U6 small nuclear ribonucleoprotein Prp3 OS=Homo sapiens OX=9606 GN=PRPF3 PE=1 SV=2 4.78 2612.9 - 1.16E+06 - - - 1.4711 - 2.627 0.496 - 134.5 1 2 1 0.0032 19 0 0 0 5.53E+07 2.40E+07 - - - 3.869 1 221125_WJC_METTL3_EV_vs_WT_F07.14972.14972.3 1.36E-06 16/60 R.DGTGHYLC[160.03]NAC[160.03]GLYSK.M sp|Q92908|GATA6_HUMAN 1 1814.7716 3 101924 14972 3 1814.771896 605.9311 Transcription factor GATA-6 OS=Homo sapiens OX=9606 GN=GATA6 PE=1 SV=2 6.72 2613.6 - 745552 - - - 0.1609 - 2.621 0.586 - 293.9 1 2 0 0.0003 16 0 0 0 7.31E+06 2.44E+06 - - - 7.5456 0.9999 221125_WJC_METTL3_EV_vs_WT_F07.14973.14973.4 1.33E-06 21/90 R.SKVDEAVAVLQAHQAK.E "sp|Q9H361|PABP3_HUMAN,sp|P11940|PABP1_HUMAN,tr|H0YAS6|H0YAS6_HUMAN,tr|H0YB75|H0YB75_HUMAN,tr|H0YAS7|H0YAS7_HUMAN,tr|A0A7I2YQE4|A0A7I2YQE4_HUMAN,tr|A0A7I2V649|A0A7I2V649_HUMAN,tr|H0YC10|H0YC10_HUMAN,tr|H0YAR2|H0YAR2_HUMAN,tr|E7ERJ7|E7ERJ7_HUMAN,tr|A0A7I2YQ88|A0A7I2YQ88_HUMAN,tr|A0A087WTT1|A0A087WTT1_HUMAN,tr|A0A7I2YQ90|A0A7I2YQ90_HUMAN,tr|A0A7I2V4N4|A0A7I2V4N4_HUMAN,tr|E7EQV3|E7EQV3_HUMAN" 15 1692.9159 1.47 101925 14973 4 1692.915668 424.2362 Polyadenylate-binding protein 3 OS=Homo sapiens OX=9606 GN=PABPC3 PE=1 SV=2 6.47 2613.7 - 496788 - - - -0.127 - 3.275 0.489 - 407.3 1 2 1 -0.0002 16 0 0 0 3.14E+08 2.14E+08 - - - 3.9001 0.9816 221125_WJC_METTL3_EV_vs_WT_F07.14974.14974.4 0.169 Nov-66 K.QR[166.11]VESHFDLELR[166.11].A "sp|Q6P2Q9|PRP8_HUMAN,tr|I3L0J9|I3L0J9_HUMAN" 2 1547.7959 1.42 101926 14974 4 1547.793899 387.9563 Pre-mRNA-processing-splicing factor 8 OS=Homo sapiens OX=9606 GN=PRPF8 PE=1 SV=2 5.45 2613.8 - 111989 - - - -1.3122 - 2.069 0.223 - 126.6 1 2 1 -0.002 12 0 0 0 1.46E+07 1.03E+07 - - - 1.4416 1 221125_WJC_METTL3_EV_vs_WT_F07.14976.14976.3 1.89E-09 20/76 K.KPSAAPEAGASALPNPPALK.K "sp|P39880|CUX1_HUMAN,tr|A0A2R8Y852|A0A2R8Y852_HUMAN,tr|A0A2R8YDI1|A0A2R8YDI1_HUMAN" 3 1886.0262 1.82 101927 14976 3 1886.02722 629.6827 Homeobox protein cut-like 1 OS=Homo sapiens OX=9606 GN=CUX1 PE=1 SV=3 8.59 2614.1 - 1.25E+06 - - - 0.561 - 3.64 0.596 - 362.7 1 2 0 0.0011 20 0 0 0 2.67E+07 1.47E+07 - - - 8.3189 0.9999 221125_WJC_METTL3_EV_vs_WT_F07.14978.14978.3 1.68E-09 17/60 R.SK[136.11]VDEAVAVLQAHQAK[136.11].E "sp|Q9H361|PABP3_HUMAN,sp|P11940|PABP1_HUMAN,tr|H0YAS6|H0YAS6_HUMAN,tr|H0YB75|H0YB75_HUMAN,tr|H0YAS7|H0YAS7_HUMAN,tr|A0A7I2YQE4|A0A7I2YQE4_HUMAN,tr|A0A7I2V649|A0A7I2V649_HUMAN,tr|H0YC10|H0YC10_HUMAN,tr|H0YAR2|H0YAR2_HUMAN,tr|E7ERJ7|E7ERJ7_HUMAN,tr|A0A7I2YQ88|A0A7I2YQ88_HUMAN,tr|A0A087WTT1|A0A087WTT1_HUMAN,tr|A0A7I2YQ90|A0A7I2YQ90_HUMAN,tr|A0A7I2V4N4|A0A7I2V4N4_HUMAN,tr|E7EQV3|E7EQV3_HUMAN" 15 1708.9443 1.42 101928 14978 3 1708.94339 570.6554 Polyadenylate-binding protein 3 OS=Homo sapiens OX=9606 GN=PABPC3 PE=1 SV=2 6.47 2614.3 - 3.82E+06 - - - -0.5225 - 3.213 0.545 - 306.4 1 2 1 -0.0009 16 0 0 0 8.34E+08 5.89E+08 - - - 7.6109 0.9876 221125_WJC_METTL3_EV_vs_WT_F07.14980.14980.3 0.236 Aug-36 K.QK[136.11]VEHIEWFR[166.11].N sp|Q92665|RT31_HUMAN 1 1388.732 1.68 101930 14980 3 1388.73255 463.9179 "28S ribosomal protein S31, mitochondrial OS=Homo sapiens OX=9606 GN=MRPS31 PE=1 SV=3" 6.76 2614.4 - 1.02E+06 - - - 0.404 - 1.788 0.214 - 91.3 1 2 1 0.0006 10 0 0 0 1.83E+07 1.09E+07 - - - 2.6228 0.9996 221125_WJC_METTL3_EV_vs_WT_F07.14982.14982.4 0.00388 17/78 R.DFKEERPEEYESWR.E "sp|Q14241|ELOA1_HUMAN,tr|A0A024RAC6|A0A024RAC6_HUMAN" 2 1898.8435 0.67 101932 14982 4 1898.842956 475.7182 Elongin-A OS=Homo sapiens OX=9606 GN=ELOA PE=1 SV=2 4.42 2614.6 - 742650 - - - -0.2896 - 2.256 0.415 - 179.7 1 2 1 -0.0006 14 0 0 0 7.64E+06 1.13E+07 - - - 3.1341 0.9985 221125_WJC_METTL3_EV_vs_WT_F07.14983.14983.3 9.53E-08 15/56 A.SAVPELATDPELEK[136.11]K[136.11].L "sp|Q86U44|MTA70_HUMAN,tr|B4E349|B4E349_HUMAN,tr|F5H6D8|F5H6D8_HUMAN,tr|H0YFV6|H0YFV6_HUMAN,tr|B4DTN4|B4DTN4_HUMAN" 5 1641.8796 1.67 101933 14983 3 1641.880723 548.3005 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 4.41 2614.8 - 664265 - - - 0.673 - 2.94 0.56 - 234.2 1 1 0 0.0011 15 0 0 0 1.55E+07 9.30E+06 - - - 7.5971 1 221125_WJC_METTL3_EV_vs_WT_F07.14986.14986.2 5.51E-09 17/34 R.EQLSSANHSLQLASQIQK.A "sp|Q13948|CASP_HUMAN,sp|P39880|CUX1_HUMAN,tr|A0A2R8Y852|A0A2R8Y852_HUMAN,tr|A0A2R8YDI1|A0A2R8YDI1_HUMAN" 4 1981.0229 1.79 101936 14986 2 1981.025889 991.5187 Protein CASP OS=Homo sapiens OX=9606 GN=CUX1 PE=1 SV=2 6.85 2615.1 - 280645 - - - 1.525 - 3.881 0.617 - 718.3 1 2 0 0.003 18 0 0 0 3.48E+06 1.95E+06 - - - 6.9312 1 221125_WJC_METTL3_EV_vs_WT_F07.14990.14990.3 7.69E-05 22/60 R.SKVDEAVAVLQAHQAK.E "sp|Q9H361|PABP3_HUMAN,sp|P11940|PABP1_HUMAN,tr|H0YAS6|H0YAS6_HUMAN,tr|H0YB75|H0YB75_HUMAN,tr|H0YAS7|H0YAS7_HUMAN,tr|A0A7I2YQE4|A0A7I2YQE4_HUMAN,tr|A0A7I2V649|A0A7I2V649_HUMAN,tr|H0YC10|H0YC10_HUMAN,tr|H0YAR2|H0YAR2_HUMAN,tr|E7ERJ7|E7ERJ7_HUMAN,tr|A0A7I2YQ88|A0A7I2YQ88_HUMAN,tr|A0A087WTT1|A0A087WTT1_HUMAN,tr|A0A7I2YQ90|A0A7I2YQ90_HUMAN,tr|A0A7I2V4N4|A0A7I2V4N4_HUMAN,tr|E7EQV3|E7EQV3_HUMAN" 15 1692.9159 1.42 101938 14990 3 1692.917415 565.3126 Polyadenylate-binding protein 3 OS=Homo sapiens OX=9606 GN=PABPC3 PE=1 SV=2 6.47 2615.6 - 7.97E+06 - - - 0.9049 - 3.922 0.563 - 658.4 1 2 1 0.0015 16 0 0 0 8.34E+08 5.89E+08 - - - 8.323 0.9998 221125_WJC_METTL3_EV_vs_WT_F07.14992.14992.4 1.40E-05 16/90 R.SK[136.11]VDEAVAVLQAHQAK[136.11].E "sp|Q9H361|PABP3_HUMAN,sp|P11940|PABP1_HUMAN,tr|H0YAS6|H0YAS6_HUMAN,tr|H0YB75|H0YB75_HUMAN,tr|H0YAS7|H0YAS7_HUMAN,tr|A0A7I2YQE4|A0A7I2YQE4_HUMAN,tr|A0A7I2V649|A0A7I2V649_HUMAN,tr|H0YC10|H0YC10_HUMAN,tr|H0YAR2|H0YAR2_HUMAN,tr|E7ERJ7|E7ERJ7_HUMAN,tr|A0A7I2YQ88|A0A7I2YQ88_HUMAN,tr|A0A087WTT1|A0A087WTT1_HUMAN,tr|A0A7I2YQ90|A0A7I2YQ90_HUMAN,tr|A0A7I2V4N4|A0A7I2V4N4_HUMAN,tr|E7EQV3|E7EQV3_HUMAN" 15 1708.9443 1.47 101940 14992 4 1708.942923 428.2433 Polyadenylate-binding protein 3 OS=Homo sapiens OX=9606 GN=PABPC3 PE=1 SV=2 6.47 2615.7 - 3.44E+06 - - - -0.7958 - 2.435 0.46 - 229.7 1 2 1 -0.0014 16 0 0 0 3.14E+08 2.14E+08 - - - 3.543 0.9998 221125_WJC_METTL3_EV_vs_WT_F07.15002.15002.4 2.61E-05 18/84 K.LKEDISQGVHISVYR.V sp|O43395|PRPF3_HUMAN 1 1742.9315 1.83 101948 15002 4 1742.93163 436.7402 U4\U6 small nuclear ribonucleoprotein Prp3 OS=Homo sapiens OX=9606 GN=PRPF3 PE=1 SV=2 6.75 2616.8 - 1.52E+06 - - - 0.0551 - 3.182 0.468 - 327.5 1 2 1 0.0001 15 0 0 0 9.43E+07 5.16E+07 - - - 3.7136 0.9999 221125_WJC_METTL3_EV_vs_WT_F07.15004.15004.3 1.13E-07 16/56 K.LKEDISQGVHISVYR.V sp|O43395|PRPF3_HUMAN 1 1742.9315 1.95 101950 15004 3 1742.933417 581.9845 U4\U6 small nuclear ribonucleoprotein Prp3 OS=Homo sapiens OX=9606 GN=PRPF3 PE=1 SV=2 6.75 2617 - 872524 - - - 1.0804 - 3.089 0.512 - 248 1 2 1 0.0019 15 0 0 0 6.09E+07 3.13E+07 - - - 7.1907 1 221125_WJC_METTL3_EV_vs_WT_F07.15005.15005.3 3.75E-12 23/64 R.TIEQNINNLNVSEADRK.C "sp|Q15003|CND2_HUMAN,tr|C9J470|C9J470_HUMAN,tr|E9PHA2|E9PHA2_HUMAN" 3 1956.9865 1.22 101951 15005 3 1956.986259 653.3361 Condensin complex subunit 2 OS=Homo sapiens OX=9606 GN=NCAPH PE=1 SV=3 4.68 2617.1 - 759871 - - - -0.114 - 3.513 0.685 - 342.1 1 2 0 -0.0002 17 0 0 0 3.64E+07 2.98E+07 - - - 9.3512 0.9564 221125_WJC_METTL3_EV_vs_WT_F07.15006.15006.2 0.00783 16-Oct V.AVLQAHQAK[136.11].E "sp|Q9H361|PABP3_HUMAN,sp|P11940|PABP1_HUMAN,tr|H0YAS6|H0YAS6_HUMAN,tr|H0YB75|H0YB75_HUMAN,tr|H0YAS7|H0YAS7_HUMAN,tr|A0A7I2YQE4|A0A7I2YQE4_HUMAN,tr|A0A7I2V649|A0A7I2V649_HUMAN,tr|H0YC10|H0YC10_HUMAN,tr|H0YAR2|H0YAR2_HUMAN,tr|E7ERJ7|E7ERJ7_HUMAN,tr|A0A7I2YQ88|A0A7I2YQ88_HUMAN,tr|A0A087WTT1|A0A087WTT1_HUMAN,tr|A0A7I2YQ90|A0A7I2YQ90_HUMAN,tr|A0A7I2V4N4|A0A7I2V4N4_HUMAN,tr|E7EQV3|E7EQV3_HUMAN" 15 972.5596 1.13 101952 15006 2 972.557915 487.2871 Polyadenylate-binding protein 3 OS=Homo sapiens OX=9606 GN=PABPC3 PE=1 SV=2 8.8 2617.3 - 520833 - - - -1.7469 - 1.791 0.336 - 338.8 1 1 0 -0.0017 9 0 0 0 2.83E+07 2.50E+07 - - - 3.2082 0.9884 221125_WJC_METTL3_EV_vs_WT_F07.15008.15008.3 0.0693 Nov-52 K.GSLAADK[136.11]VVEEIR[166.11]R[166.11].R "sp|P51659|DHB4_HUMAN,tr|A0A804HK88|A0A804HK88_HUMAN,tr|A0A2R8YD50|A0A2R8YD50_HUMAN,tr|A0A804HKB5|A0A804HKB5_HUMAN,tr|E7ER27|E7ER27_HUMAN,tr|A0A2R8YF45|A0A2R8YF45_HUMAN,tr|E7EPL9|E7EPL9_HUMAN,tr|A0A804HKU2|A0A804HKU2_HUMAN,tr|A0A2R8YDT8|A0A2R8YDT8_HUMAN,tr|A0A804HK65|A0A804HK65_HUMAN" 10 1569.8833 0.9 101954 15008 3 1569.884337 524.3017 Peroxisomal multifunctional enzyme type 2 OS=Homo sapiens OX=9606 GN=HSD17B4 PE=1 SV=3 6.18 2617.5 - 351085 - - - 0.6637 - 1.839 0.225 - 132 1 2 1 0.001 14 0 0 0 4.13E+06 4.60E+06 - - - 2.6673 1 221125_WJC_METTL3_EV_vs_WT_F07.15010.15010.2 4.72E-09 18/30 R.SK[136.11]VDEAVAVLQAHQAK[136.11].E "sp|Q9H361|PABP3_HUMAN,sp|P11940|PABP1_HUMAN,tr|H0YAS6|H0YAS6_HUMAN,tr|H0YB75|H0YB75_HUMAN,tr|H0YAS7|H0YAS7_HUMAN,tr|A0A7I2YQE4|A0A7I2YQE4_HUMAN,tr|A0A7I2V649|A0A7I2V649_HUMAN,tr|H0YC10|H0YC10_HUMAN,tr|H0YAR2|H0YAR2_HUMAN,tr|E7ERJ7|E7ERJ7_HUMAN,tr|A0A7I2YQ88|A0A7I2YQ88_HUMAN,tr|A0A087WTT1|A0A087WTT1_HUMAN,tr|A0A7I2YQ90|A0A7I2YQ90_HUMAN,tr|A0A7I2V4N4|A0A7I2V4N4_HUMAN,tr|E7EQV3|E7EQV3_HUMAN" 15 1708.9443 1.52 101956 15010 2 1708.947835 855.4794 Polyadenylate-binding protein 3 OS=Homo sapiens OX=9606 GN=PABPC3 PE=1 SV=2 6.47 2617.8 - 293216 - - - 2.0785 - 3.827 0.667 - 1255.4 1 2 1 0.0036 16 0 0 0 1.97E+07 1.30E+07 - - - 7.2659 0.9998 221125_WJC_METTL3_EV_vs_WT_F07.15011.15011.2 0.00239 Dec-34 K.ASSSSASSAGALESSLDR.K sp|Q5VT52|RPRD2_HUMAN 1 1681.7755 1.87 101957 15011 2 1681.779184 841.895 Regulation of nuclear pre-mRNA domain-containing protein 2 OS=Homo sapiens OX=9606 GN=RPRD2 PE=1 SV=1 4.37 2617.9 - 228502 - - - 2.1989 - 2.786 0.526 - 421.3 1 2 0 0.0037 18 0 0 0 5.16E+06 2.76E+06 - - - 5.4439 0.9978 221125_WJC_METTL3_EV_vs_WT_F07.15015.15015.3 0.0163 Dec-40 K.TRLEQEIATYR.R "sp|Q04695|K1C17_HUMAN,sp|P02533|K1C14_HUMAN,sp|P35900|K1C20_HUMAN,sp|P08779|K1C16_HUMAN,sp|P19012|K1C15_HUMAN,sp|P13646|K1C13_HUMAN,tr|A0A3B3IS58|A0A3B3IS58_HUMAN,tr|F5GWP8|F5GWP8_HUMAN,tr|K7ERE3|K7ERE3_HUMAN,tr|A8MT21|A8MT21_HUMAN" 10 1378.7205 124.21 101959 15015 3 1378.7203 460.5808 "Keratin, type I cytoskeletal 17 OS=Homo sapiens OX=9606 GN=KRT17 PE=1 SV=2" 5.81 2618.5 - 2.62E+06 - - - -0.1291 - 2.035 0.295 - 222.3 1 2 1 -0.0002 11 0 0 0 3.90E+07 3.14E+05 - - - 3.8473 0.9996 221125_WJC_METTL3_EV_vs_WT_F07.15016.15016.4 4.98E-06 15/84 K.LK[136.11]EDISQGVHISVYR[166.11].V sp|O43395|PRPF3_HUMAN 1 1760.954 1.83 101960 15016 4 1760.950687 441.2458 U4\U6 small nuclear ribonucleoprotein Prp3 OS=Homo sapiens OX=9606 GN=PRPF3 PE=1 SV=2 6.75 2618.5 - 2.23E+06 - - - -1.8836 - 2.509 0.44 - 229 1 2 1 -0.0033 15 0 0 0 9.56E+07 5.22E+07 - - - 3.384 0.9982 221125_WJC_METTL3_EV_vs_WT_F07.15017.15017.3 0.000289 Nov-36 K.QKVEHIEWFR.N sp|Q92665|RT31_HUMAN 1 1370.7095 1.69 101961 15017 3 1370.709122 457.9104 "28S ribosomal protein S31, mitochondrial OS=Homo sapiens OX=9606 GN=MRPS31 PE=1 SV=3" 6.76 2618.6 - 1.16E+06 - - - -0.2896 - 2.195 0.283 - 249.5 1 2 1 -0.0004 10 0 0 0 1.83E+07 1.09E+07 - - - 3.9911 0.9779 221125_WJC_METTL3_EV_vs_WT_F07.15018.15018.2 0.00399 16-Dec V.AVLQAHQAK.E "sp|Q9H361|PABP3_HUMAN,sp|P11940|PABP1_HUMAN,tr|H0YAS6|H0YAS6_HUMAN,tr|H0YB75|H0YB75_HUMAN,tr|H0YAS7|H0YAS7_HUMAN,tr|A0A7I2YQE4|A0A7I2YQE4_HUMAN,tr|A0A7I2V649|A0A7I2V649_HUMAN,tr|H0YC10|H0YC10_HUMAN,tr|H0YAR2|H0YAR2_HUMAN,tr|E7ERJ7|E7ERJ7_HUMAN,tr|A0A7I2YQ88|A0A7I2YQ88_HUMAN,tr|A0A087WTT1|A0A087WTT1_HUMAN,tr|A0A7I2YQ90|A0A7I2YQ90_HUMAN,tr|A0A7I2V4N4|A0A7I2V4N4_HUMAN,tr|E7EQV3|E7EQV3_HUMAN" 15 964.5454 1.13 101962 15018 2 964.546886 483.28 Polyadenylate-binding protein 3 OS=Homo sapiens OX=9606 GN=PABPC3 PE=1 SV=2 8.8 2618.7 - 1.12E+06 - - - 1.5261 - 2.054 0.387 - 482 1 1 0 0.0015 9 0 0 0 2.83E+07 2.50E+07 - - - 3.9813 1 221125_WJC_METTL3_EV_vs_WT_F07.15020.15020.2 5.63E-10 21/30 R.SKVDEAVAVLQAHQAK.E "sp|Q9H361|PABP3_HUMAN,sp|P11940|PABP1_HUMAN,tr|H0YAS6|H0YAS6_HUMAN,tr|H0YB75|H0YB75_HUMAN,tr|H0YAS7|H0YAS7_HUMAN,tr|A0A7I2YQE4|A0A7I2YQE4_HUMAN,tr|A0A7I2V649|A0A7I2V649_HUMAN,tr|H0YC10|H0YC10_HUMAN,tr|H0YAR2|H0YAR2_HUMAN,tr|E7ERJ7|E7ERJ7_HUMAN,tr|A0A7I2YQ88|A0A7I2YQ88_HUMAN,tr|A0A087WTT1|A0A087WTT1_HUMAN,tr|A0A7I2YQ90|A0A7I2YQ90_HUMAN,tr|A0A7I2V4N4|A0A7I2V4N4_HUMAN,tr|E7EQV3|E7EQV3_HUMAN" 15 1692.9159 1.52 101964 15020 2 1692.91517 847.4652 Polyadenylate-binding protein 3 OS=Homo sapiens OX=9606 GN=PABPC3 PE=1 SV=2 6.47 2619 - 584752 - - - -0.4212 - 4.086 0.677 - 1739.7 1 2 1 -0.0007 16 0 0 0 1.97E+07 1.30E+07 - - - 7.5017 0.9998 221125_WJC_METTL3_EV_vs_WT_F07.15021.15021.4 8.82E-06 18/78 R.SKEAEAAFLNVYKR.L "sp|Q13948|CASP_HUMAN,sp|P39880|CUX1_HUMAN,tr|A0A2R8Y852|A0A2R8Y852_HUMAN,tr|A0A2R8YDI1|A0A2R8YDI1_HUMAN" 4 1624.8573 1.8 101965 15021 4 1624.859496 407.2216 Protein CASP OS=Homo sapiens OX=9606 GN=CUX1 PE=1 SV=2 8.22 2619.1 - 486016 - - - 1.3478 - 2.957 0.479 - 239.8 1 2 1 0.0022 14 0 0 0 5.64E+06 3.14E+06 - - - 3.7892 0.9997 221125_WJC_METTL3_EV_vs_WT_F07.15022.15022.4 0.00424 Nov-66 R.FHWEQDQIAHMK[136.11].N sp|Q9UG63|ABCF2_HUMAN 1 1576.7336 0.63 101966 15022 4 1576.7344 395.1907 ATP-binding cassette sub-family F member 2 OS=Homo sapiens OX=9606 GN=ABCF2 PE=1 SV=2 5.99 2619.2 - 454498 - - - 0.4871 - 1.691 0.363 - 141.6 1 2 0 0.0008 12 0 0 0 3.20E+06 5.12E+06 - - - 2.5841 1 221125_WJC_METTL3_EV_vs_WT_F07.15023.15023.3 5.67E-08 18/96 R.VYFQSPPGAAGEGPGGADDEGPVR[166.11]R[166.11].Q sp|Q96C90|PP14B_HUMAN 1 2505.1788 1.43 101967 15023 3 2505.175795 836.0669 Protein phosphatase 1 regulatory subunit 14B OS=Homo sapiens OX=9606 GN=PPP1R14B PE=1 SV=3 4.32 2619.4 - 378086 - - - -1.1816 - 2.641 0.57 - 288 1 2 0 -0.003 25 0 0 0 6.13E+06 4.30E+06 - - - 7.1284 0.9999 221125_WJC_METTL3_EV_vs_WT_F07.15031.15031.3 3.13E-06 16/56 K.LK[136.11]EDISQGVHISVYR[166.11].V sp|O43395|PRPF3_HUMAN 1 1760.954 1.93 101973 15031 3 1760.951748 587.9919 U4\U6 small nuclear ribonucleoprotein Prp3 OS=Homo sapiens OX=9606 GN=PRPF3 PE=1 SV=2 6.75 2620.4 - 2.17E+06 - - - -1.2811 - 2.972 0.549 - 212.5 1 2 1 -0.0023 15 0 0 0 6.05E+07 3.13E+07 - - - 7.5024 0.9974 221125_WJC_METTL3_EV_vs_WT_F07.15035.15035.4 0.018 14/66 K.QRVESHFDLELR.A "sp|Q6P2Q9|PRP8_HUMAN,tr|I3L0J9|I3L0J9_HUMAN" 2 1527.7794 1.42 101977 15035 4 1527.779086 382.9521 Pre-mRNA-processing-splicing factor 8 OS=Homo sapiens OX=9606 GN=PRPF8 PE=1 SV=2 5.45 2620.8 - 959197 - - - -0.199 - 2.132 0.314 - 196.5 1 2 1 -0.0003 12 0 0 0 1.48E+07 1.04E+07 - - - 2.2455 0.9922 221125_WJC_METTL3_EV_vs_WT_F07.15037.15037.3 1.00E-06 16/56 L.SFETTDDSLREHFEK.W "sp|P51991|ROA3_HUMAN,tr|A0A7I2V5D8|A0A7I2V5D8_HUMAN,tr|A0A7I2V2R3|A0A7I2V2R3_HUMAN,tr|A0A7I2V4J6|A0A7I2V4J6_HUMAN,tr|A0A7I2V4G0|A0A7I2V4G0_HUMAN,tr|A0A7I2V402|A0A7I2V402_HUMAN" 6 1839.8275 1.92 101979 15037 3 1839.826317 614.2831 Heterogeneous nuclear ribonucleoprotein A3 OS=Homo sapiens OX=9606 GN=HNRNPA3 PE=1 SV=2 4.5 2621.1 - 788108 - - - -0.655 - 2.729 0.558 - 190.6 1 1 1 -0.0012 15 0 0 0 1.99E+07 1.04E+07 - - - 7.3804 0.9999 221125_WJC_METTL3_EV_vs_WT_F07.15038.15038.3 0.0089 20/44 K.FEK[136.11]DQIIDSLK[136.11]R[166.11].G "sp|Q6P3W7|SCYL2_HUMAN,tr|F8VSC5|F8VSC5_HUMAN,tr|A0A0U1RQQ9|A0A0U1RQQ9_HUMAN" 3 1516.846 4.74 101980 15038 3 1516.844633 506.6226 SCY1-like protein 2 OS=Homo sapiens OX=9606 GN=SCYL2 PE=1 SV=1 6.12 2621.2 - 694445 - - - -0.8768 - 3.38 0.424 - 604.3 1 2 1 -0.0013 12 0 0 0 1.20E+08 2.53E+07 - - - 6.6426 0.9615 221125_WJC_METTL3_EV_vs_WT_F07.15039.15039.3 2.97E-06 15/56 L.SFETTDDSLR[166.11]EHFEK[136.11].W "sp|P51991|ROA3_HUMAN,tr|A0A7I2V5D8|A0A7I2V5D8_HUMAN,tr|A0A7I2V2R3|A0A7I2V2R3_HUMAN,tr|A0A7I2V4J6|A0A7I2V4J6_HUMAN,tr|A0A7I2V4G0|A0A7I2V4G0_HUMAN,tr|A0A7I2V402|A0A7I2V402_HUMAN" 6 1857.85 1.88 101981 15039 3 1857.846719 620.2906 Heterogeneous nuclear ribonucleoprotein A3 OS=Homo sapiens OX=9606 GN=HNRNPA3 PE=1 SV=2 4.5 2621.3 - 672930 - - - -1.7617 - 3.064 0.391 - 134.6 1 1 1 -0.0033 15 0 0 0 1.86E+07 9.90E+06 - - - 5.8201 0.9999 221125_WJC_METTL3_EV_vs_WT_F07.15041.15041.4 2.90E-11 14/90 R.GYHQYAYDGK[136.11]DYIALK[136.11].E "tr|Q53Z42|Q53Z42_HUMAN,tr|A0A140T955|A0A140T955_HUMAN,tr|A0A140T913|A0A140T913_HUMAN,tr|A0A1W2PPQ2|A0A1W2PPQ2_HUMAN,tr|A0A140T933|A0A140T933_HUMAN,tr|A0A1W2PRT9|A0A1W2PRT9_HUMAN,tr|A0A140T9I0|A0A140T9I0_HUMAN,tr|A0A140T9X5|A0A140T9X5_HUMAN" 8 1919.9389 0.74 101983 15041 4 1919.940218 480.992 HLA class I antigen OS=Homo sapiens OX=9606 GN=HLA-A PE=1 SV=1 6.74 2621.6 - 538601 - - - 0.7052 - 3.046 0.62 - 109.8 1 2 1 0.0014 16 0 0 0 4.21E+06 5.67E+06 - - - 5.0145 0.9961 221125_WJC_METTL3_EV_vs_WT_F07.15043.15043.4 0.252 18/66 K.FEK[136.11]DQIIDSLK[136.11]R[166.11].G "sp|Q6P3W7|SCYL2_HUMAN,tr|F8VSC5|F8VSC5_HUMAN,tr|A0A0U1RQQ9|A0A0U1RQQ9_HUMAN" 3 1516.846 0.001 101985 15043 4 1516.8454 380.2188 SCY1-like protein 2 OS=Homo sapiens OX=9606 GN=SCYL2 PE=1 SV=1 6.12 2621.8 - 457669 - - - -0.3712 - 2.974 0.278 - 183.3 1 2 1 -0.0006 12 0 0 0 0.00E+00 1.24E+07 - - - 2.058 0.9997 221125_WJC_METTL3_EV_vs_WT_F07.15048.15048.3 3.29E-09 18/44 K.FEKDQIIDSLKR.G "sp|Q6P3W7|SCYL2_HUMAN,tr|F8VSC5|F8VSC5_HUMAN,tr|A0A0U1RQQ9|A0A0U1RQQ9_HUMAN" 3 1490.8093 1.71 101988 15048 3 1490.808629 497.9437 SCY1-like protein 2 OS=Homo sapiens OX=9606 GN=SCYL2 PE=1 SV=1 6.12 2622.5 - 2.90E+06 - - - -0.4454 - 3.14 0.356 - 474.6 1 2 1 -0.0007 12 0 0 0 3.61E+07 2.12E+07 - - - 5.6805 1 221125_WJC_METTL3_EV_vs_WT_F07.15051.15051.3 3.18E-07 Dec-64 R.TIEQNINNLNVSEADR[166.11]K[136.11].C "sp|Q15003|CND2_HUMAN,tr|C9J470|C9J470_HUMAN,tr|E9PHA2|E9PHA2_HUMAN" 3 1975.009 1.22 101991 15051 3 1975.006721 659.3436 Condensin complex subunit 2 OS=Homo sapiens OX=9606 GN=NCAPH PE=1 SV=3 4.68 2622.7 - 3.15E+06 - - - -1.1296 - 2.647 0.557 - 84.3 1 2 0 -0.0022 17 0 0 0 3.65E+07 2.98E+07 - - - 7.2086 1 221125_WJC_METTL3_EV_vs_WT_F07.15052.15052.3 3.91E-10 27/64 K.KILDSVGIEADDDRLNK.V sp|P05387|RLA2_HUMAN 1 1899.9902 1.3 101992 15052 3 1899.993579 634.3373 60S acidic ribosomal protein P2 OS=Homo sapiens OX=9606 GN=RPLP2 PE=1 SV=1 4.36 2622.8 - 1.37E+06 - - - 1.7937 - 5.082 0.565 - 1320.1 1 2 1 0.0034 17 0 0 0 4.70E+08 3.62E+08 - - - 8.9453 1 221125_WJC_METTL3_EV_vs_WT_F07.15053.15053.3 9.64E-13 24/64 K.K[136.11]ILDSVGIEADDDR[166.11]LNK[136.11].V sp|P05387|RLA2_HUMAN 1 1926.0268 1.3 101993 15053 3 1926.030593 643.0162 60S acidic ribosomal protein P2 OS=Homo sapiens OX=9606 GN=RPLP2 PE=1 SV=1 4.36 2622.9 - 1.26E+06 - - - 1.9481 - 4.438 0.688 - 606.8 1 2 1 0.0038 17 0 0 0 4.70E+08 3.62E+08 - - - 9.9742 0.9997 221125_WJC_METTL3_EV_vs_WT_F07.15054.15054.3 0.000724 17/60 R.RKTDFFIGGEEGMAEK.L "sp|Q9Y266|NUDC_HUMAN,tr|A0A0A0MSU9|A0A0A0MSU9_HUMAN" 2 1813.8669 2.36 101994 15054 3 1813.868692 605.6296 Nuclear migration protein nudC OS=Homo sapiens OX=9606 GN=NUDC PE=1 SV=1 4.87 2623 - 1.05E+06 - - - 0.9968 - 2.445 0.43 - 387.7 1 2 1 0.0018 16 0 0 0 2.67E+07 1.13E+07 - - - 5.6276 1 221125_WJC_METTL3_EV_vs_WT_F07.15055.15055.3 6.81E-10 16/68 R.TPQVIGVMQSQNSSAGNR.G "sp|O95639|CPSF4_HUMAN,tr|H7C419|H7C419_HUMAN,tr|B7Z7B0|B7Z7B0_HUMAN,tr|C9JEV9|C9JEV9_HUMAN" 4 1872.9112 1.31 101995 15055 3 1872.91089 625.311 Cleavage and polyadenylation specificity factor subunit 4 OS=Homo sapiens OX=9606 GN=CPSF4 PE=1 SV=1 9.41 2623.1 - 993363 - - - -0.1703 - 3.32 0.586 - 434.6 1 2 0 -0.0003 18 0 0 0 3.86E+07 2.95E+07 - - - 8.0613 0.9974 221125_WJC_METTL3_EV_vs_WT_F07.15056.15056.4 0.0526 Oct-90 R.RKTDFFIGGEEGMAEK.L "sp|Q9Y266|NUDC_HUMAN,tr|A0A0A0MSU9|A0A0A0MSU9_HUMAN" 2 1813.8669 1.88 101996 15056 4 1813.865662 454.474 Nuclear migration protein nudC OS=Homo sapiens OX=9606 GN=NUDC PE=1 SV=1 4.87 2623.2 - 742407 - - - -0.6737 - 1.693 0.324 - 73.6 1 2 1 -0.0012 16 0 0 0 1.46E+07 7.75E+06 - - - 2.2312 0.9997 221125_WJC_METTL3_EV_vs_WT_F07.15060.15060.3 5.20E-07 14/64 K.VKEPSVQEATSTSDILK.V "sp|Q8IYB3|SRRM1_HUMAN,tr|M0R088|M0R088_HUMAN,tr|E9PCT1|E9PCT1_HUMAN,tr|A9Z1X7|A9Z1X7_HUMAN" 4 1830.9575 0.62 102000 15060 3 1830.960496 611.3264 Serine\arginine repetitive matrix protein 1 OS=Homo sapiens OX=9606 GN=SRRM1 PE=1 SV=2 4.68 2623.8 - 309785 - - - 1.6505 - 2.663 0.475 - 182.1 1 2 1 0.003 17 0 0 0 1.09E+07 1.76E+07 - - - 6.3093 1 221125_WJC_METTL3_EV_vs_WT_F07.15061.15061.2 2.88E-09 19/34 R.TPQVIGVMQSQNSSAGNR.G "sp|O95639|CPSF4_HUMAN,tr|H7C419|H7C419_HUMAN,tr|B7Z7B0|B7Z7B0_HUMAN,tr|C9JEV9|C9JEV9_HUMAN" 4 1872.9112 1.39 102001 15061 2 1872.91288 937.4629 Cleavage and polyadenylation specificity factor subunit 4 OS=Homo sapiens OX=9606 GN=CPSF4 PE=1 SV=1 9.41 2623.9 - 247788 - - - 0.8922 - 3.653 0.685 - 983.1 1 2 0 0.0017 18 0 0 0 9.32E+06 6.70E+06 - - - 7.2851 0.9999 221125_WJC_METTL3_EV_vs_WT_F07.15063.15063.4 4.48E-07 19/96 K.KILDSVGIEADDDRLNK.V sp|P05387|RLA2_HUMAN 1 1899.9902 1.27 102002 15063 4 1899.991218 476.0048 60S acidic ribosomal protein P2 OS=Homo sapiens OX=9606 GN=RPLP2 PE=1 SV=1 4.36 2624.1 - 3.24E+06 - - - 0.5511 - 3.689 0.561 - 271.6 1 2 1 0.001 17 0 0 0 3.00E+08 2.36E+08 - - - 4.5619 0.9997 221125_WJC_METTL3_EV_vs_WT_F07.15065.15065.4 1.78E-05 18/96 K.K[136.11]ILDSVGIEADDDR[166.11]LNK[136.11].V sp|P05387|RLA2_HUMAN 1 1926.0268 1.27 102003 15065 4 1926.024872 482.514 60S acidic ribosomal protein P2 OS=Homo sapiens OX=9606 GN=RPLP2 PE=1 SV=1 4.36 2624.3 - 4.81E+06 - - - -1.0223 - 2.433 0.453 - 165.8 1 2 1 -0.002 17 0 0 0 3.00E+08 2.36E+08 - - - 3.4771 1 221125_WJC_METTL3_EV_vs_WT_F07.15066.15066.3 1.48E-06 14/68 R.TPQVIGVMQSQNSSAGNR[166.11].G "sp|O95639|CPSF4_HUMAN,tr|H7C419|H7C419_HUMAN,tr|B7Z7B0|B7Z7B0_HUMAN,tr|C9JEV9|C9JEV9_HUMAN" 4 1882.9195 1.31 102004 15066 3 1882.919273 628.6471 Cleavage and polyadenylation specificity factor subunit 4 OS=Homo sapiens OX=9606 GN=CPSF4 PE=1 SV=1 9.41 2624.4 - 1.38E+06 - - - -0.1094 - 3.107 0.519 - 308.6 1 2 0 -0.0002 18 0 0 0 3.86E+07 2.94E+07 - - - 7.1492 1 221125_WJC_METTL3_EV_vs_WT_F07.15067.15067.4 1.18E-05 19/84 R.VLSAPPHFHFGQTNR[166.11].T sp|P26641|EF1G_HUMAN 1 1716.8724 0.92 102005 15067 4 1716.87124 430.2254 Elongation factor 1-gamma OS=Homo sapiens OX=9606 GN=EEF1G PE=1 SV=3 9.73 2624.5 - 2.09E+06 - - - -0.6716 - 3.351 0.557 - 478.2 1 2 0 -0.0012 15 0 0 0 4.63E+07 5.04E+07 - - - 4.5065 1 221125_WJC_METTL3_EV_vs_WT_F07.15073.15073.3 1.39E-10 15/92 R.IR[166.11]GPEESQPPQLYAADEEEAPGTR[166.11].D sp|Q5RKV6|EXOS6_HUMAN 1 2659.2629 1.63 102011 15073 3 2659.266697 887.4282 Exosome complex component MTR3 OS=Homo sapiens OX=9606 GN=EXOSC6 PE=1 SV=1 4.14 2625.2 - 322520 - - - 1.4357 - 3.501 0.634 - 183.2 1 2 1 0.0038 24 0 0 0 4.46E+06 2.74E+06 - - - 8.5177 1 221125_WJC_METTL3_EV_vs_WT_F07.15074.15074.2 1.36E-12 17/34 K.SPGSSWQEYGPSDTC[160.03]GSR[166.11].R sp|Q5JSZ5|PRC2B_HUMAN 1 1966.7991 1.19 102012 15074 2 1966.799742 984.4068 Protein PRRC2B OS=Homo sapiens OX=9606 GN=PRRC2B PE=1 SV=2 4.37 2625.3 - 262676 - - - 0.332 - 3.511 0.799 - 690.2 1 2 0 0.0007 18 0 0 0 4.91E+06 4.13E+06 - - - 8.0299 1 221125_WJC_METTL3_EV_vs_WT_F07.15076.15076.4 0.0026 14/84 K.THINIVVIGHVDSGK[136.11].S "sp|Q05639|EF1A2_HUMAN,sp|P68104|EF1A1_HUMAN,sp|Q5VTE0|EF1A3_HUMAN,tr|A0A2R8Y488|A0A2R8Y488_HUMAN,tr|A0A2R8YDN5|A0A2R8YDN5_HUMAN,tr|A0A7I2V659|A0A7I2V659_HUMAN,tr|A0A7I2V3H3|A0A7I2V3H3_HUMAN,tr|Q5JR01|Q5JR01_HUMAN,tr|A0A2U3TZH3|A0A2U3TZH3_HUMAN,tr|A0A7I2V5N4|A0A7I2V5N4_HUMAN,tr|A0A087WVQ9|A0A087WVQ9_HUMAN,tr|A6PW80|A6PW80_HUMAN,tr|A0A087WV01|A0A087WV01_HUMAN,tr|A0A2R8Y660|A0A2R8Y660_HUMAN,tr|A0A6Q8PFK6|A0A6Q8PFK6_HUMAN" 15 1595.8875 0.38 102013 15076 4 1595.886441 399.9791 Elongation factor 1-alpha 2 OS=Homo sapiens OX=9606 GN=EEF1A2 PE=1 SV=1 6.61 2625.6 - 3.79E+06 - - - -0.6573 - 3.046 0.556 - 222.9 1 2 0 -0.001 15 0 0 0 2.49E+08 6.59E+08 - - - 4.4637 0.978 221125_WJC_METTL3_EV_vs_WT_F07.15079.15079.3 0.0133 Dec-60 A.K[136.11]NQVALNPQNTVFDAK[136.11].R "sp|P0DMV8|HS71A_HUMAN,sp|P0DMV9|HS71B_HUMAN,tr|A0A0G2JIW1|A0A0G2JIW1_HUMAN" 3 1801.9657 0.11 102015 15079 3 1801.965159 601.6625 Heat shock 70 kDa protein 1A OS=Homo sapiens OX=9606 GN=HSPA1A PE=1 SV=1 8.59 2625.9 - 799937 - - - -0.3263 - 2.142 0.36 - 138.7 1 1 0 -0.0006 16 0 0 0 1.51E+06 1.40E+07 - - - 4.508 0.9999 221125_WJC_METTL3_EV_vs_WT_F07.15080.15080.3 4.19E-07 14/64 K.VK[136.11]EPSVQEATSTSDILK[136.11].V "sp|Q8IYB3|SRRM1_HUMAN,tr|M0R088|M0R088_HUMAN,tr|E9PCT1|E9PCT1_HUMAN,tr|A9Z1X7|A9Z1X7_HUMAN" 4 1846.9859 0.62 102016 15080 3 1846.985387 616.6692 Serine\arginine repetitive matrix protein 1 OS=Homo sapiens OX=9606 GN=SRRM1 PE=1 SV=2 4.68 2626 - 1.25E+06 - - - -0.2637 - 3.038 0.562 - 236.6 1 2 1 -0.0005 17 0 0 0 1.09E+07 1.76E+07 - - - 7.6128 0.9997 221125_WJC_METTL3_EV_vs_WT_F07.15082.15082.3 0.582 17/60 K.DALAALETPGRPSQQK.R "sp|Q92547|TOPB1_HUMAN,tr|A0A2R8YD63|A0A2R8YD63_HUMAN" 2 1680.8795 0.75 102018 15082 3 1680.874499 561.3004 DNA topoisomerase 2-binding protein 1 OS=Homo sapiens OX=9606 GN=TOPBP1 PE=1 SV=3 6.07 2626.2 - 764590 - - - -2.974 - 3.254 0.343 - 452.4 1 2 0 -0.005 16 0 0 0 6.15E+06 8.22E+06 - - - 5.3902 0.9996 221125_WJC_METTL3_EV_vs_WT_F07.15084.15084.3 4.12E-07 17/64 R.HPGYSTQTHVNDLMLVK.L "sp|P49862|KLK7_HUMAN,tr|M0QYU8|M0QYU8_HUMAN" 2 1938.9622 38.58 102020 15084 3 1938.972087 647.328 Kallikrein-7 OS=Homo sapiens OX=9606 GN=KLK7 PE=1 SV=1 6.92 2626.5 - 663015 - - - 5.1084 - 2.781 0.53 - 285 1 2 0 0.0099 17 0 0 0 1.90E+07 4.92E+05 - - - 7.0302 1 221125_WJC_METTL3_EV_vs_WT_F07.15086.15086.2 7.31E-15 18/34 R.TPQVIGVMQSQNSSAGNR[166.11].G "sp|O95639|CPSF4_HUMAN,tr|H7C419|H7C419_HUMAN,tr|B7Z7B0|B7Z7B0_HUMAN,tr|C9JEV9|C9JEV9_HUMAN" 4 1882.9195 1.39 102022 15086 2 1882.916251 942.467 Cleavage and polyadenylation specificity factor subunit 4 OS=Homo sapiens OX=9606 GN=CPSF4 PE=1 SV=1 9.41 2626.7 - 438883 - - - -1.7144 - 3.874 0.753 - 912.9 1 2 0 -0.0032 18 0 0 0 9.32E+06 6.70E+06 - - - 7.9312 1 221125_WJC_METTL3_EV_vs_WT_F07.15087.15087.2 5.40E-11 19/34 K.SPGSSWQEYGPSDTC[160.03]GSR.R sp|Q5JSZ5|PRC2B_HUMAN 1 1956.7908 1.19 102023 15087 2 1956.794276 979.4027 Protein PRRC2B OS=Homo sapiens OX=9606 GN=PRRC2B PE=1 SV=2 4.37 2626.9 - 394010 - - - 1.7667 - 3.574 0.787 - 845.2 1 2 0 0.0035 18 0 0 0 4.91E+06 4.13E+06 - - - 7.9841 1 221125_WJC_METTL3_EV_vs_WT_F07.15090.15090.3 2.27E-08 16/68 K.GWSGPKPGFPEPTNNTPK.G "sp|Q9NUL3|STAU2_HUMAN,tr|E5RJN7|E5RJN7_HUMAN,tr|E7EVJ4|E7EVJ4_HUMAN,tr|E7EPX0|E7EPX0_HUMAN,tr|H0YBY0|H0YBY0_HUMAN,tr|E5RJ67|E5RJ67_HUMAN" 6 1909.9323 5.45 102024 15090 3 1909.933336 637.6514 Double-stranded RNA-binding protein Staufen homolog 2 OS=Homo sapiens OX=9606 GN=STAU2 PE=1 SV=2 8.59 2627.3 - 1.26E+06 - - - 0.5623 - 2.878 0.538 - 225 1 2 0 0.0011 18 0 0 0 2.65E+07 4.86E+06 - - - 7.1701 1 221125_WJC_METTL3_EV_vs_WT_F07.15092.15092.3 5.38E-06 15/68 R.QFDNLKPSGGYITGDQAR.N "sp|Q9NZM3|ITSN2_HUMAN,tr|A0A087WVF7|A0A087WVF7_HUMAN,tr|F8W719|F8W719_HUMAN,tr|E7EPJ2|E7EPJ2_HUMAN" 4 1965.9545 7.75 102026 15092 3 1965.953556 656.3254 Intersectin-2 OS=Homo sapiens OX=9606 GN=ITSN2 PE=1 SV=3 5.96 2627.5 - 1.16E+06 - - - -0.4568 - 2.203 0.502 - 193.3 1 2 0 -0.0009 18 0 0 0 1.87E+07 2.41E+06 - - - 6.1033 0.9998 221125_WJC_METTL3_EV_vs_WT_F07.15093.15093.4 3.04E-05 15/84 R.VK[136.11]EDDLDVVLSPQR[166.11]R[166.11].S "sp|Q9NRA8|4ET_HUMAN,tr|B1AKL5|B1AKL5_HUMAN,tr|B1AKL4|B1AKL4_HUMAN" 3 1795.9787 1.06 102027 15093 4 1795.977503 450.0019 Eukaryotic translation initiation factor 4E transporter OS=Homo sapiens OX=9606 GN=EIF4ENIF1 PE=1 SV=2 4.68 2627.6 - 570929 - - - -0.6398 - 2.788 0.448 - 193.6 1 2 1 -0.0011 15 0 0 0 1.63E+07 1.53E+07 - - - 3.4919 0.9511 221125_WJC_METTL3_EV_vs_WT_F07.15096.15096.3 0.00076 Dec-40 V.GIEADDDR[166.11]LNK[136.11].V sp|P05387|RLA2_HUMAN 1 1262.6222 1.9 102030 15096 3 1262.622805 421.8813 60S acidic ribosomal protein P2 OS=Homo sapiens OX=9606 GN=RPLP2 PE=1 SV=1 4.23 2628 - 277066 - - - 0.5077 - 1.983 0.417 - 125.2 1 1 1 0.0006 11 0 0 0 4.12E+06 2.17E+06 - - - 5.1338 1 221125_WJC_METTL3_EV_vs_WT_F07.15098.15098.3 1.61E-08 14/56 K.THINIVVIGHVDSGK.S "sp|Q05639|EF1A2_HUMAN,sp|P68104|EF1A1_HUMAN,sp|Q5VTE0|EF1A3_HUMAN,tr|A0A2R8Y488|A0A2R8Y488_HUMAN,tr|A0A2R8YDN5|A0A2R8YDN5_HUMAN,tr|A0A7I2V659|A0A7I2V659_HUMAN,tr|A0A7I2V3H3|A0A7I2V3H3_HUMAN,tr|Q5JR01|Q5JR01_HUMAN,tr|A0A2U3TZH3|A0A2U3TZH3_HUMAN,tr|A0A7I2V5N4|A0A7I2V5N4_HUMAN,tr|A0A087WVQ9|A0A087WVQ9_HUMAN,tr|A6PW80|A6PW80_HUMAN,tr|A0A087WV01|A0A087WV01_HUMAN,tr|A0A2R8Y660|A0A2R8Y660_HUMAN,tr|A0A6Q8PFK6|A0A6Q8PFK6_HUMAN" 15 1587.8733 0.38 102031 15098 3 1587.873327 530.2984 Elongation factor 1-alpha 2 OS=Homo sapiens OX=9606 GN=EEF1A2 PE=1 SV=1 6.61 2628.2 - 1.53E+06 - - - 0.0233 - 3.314 0.468 - 300.8 1 2 0 0 15 0 0 0 4.92E+08 1.30E+09 - - - 6.8842 0.9998 221125_WJC_METTL3_EV_vs_WT_F07.15103.15103.4 0.00142 17/84 R.VKEDDLDVVLSPQRR.S "sp|Q9NRA8|4ET_HUMAN,tr|B1AKL5|B1AKL5_HUMAN,tr|B1AKL4|B1AKL4_HUMAN" 3 1767.9479 1.03 102035 15103 4 1767.948453 442.9943 Eukaryotic translation initiation factor 4E transporter OS=Homo sapiens OX=9606 GN=EIF4ENIF1 PE=1 SV=2 4.68 2628.7 - 831575 - - - 0.306 - 2.751 0.464 - 234.4 1 2 1 0.0005 15 0 0 0 1.56E+07 1.51E+07 - - - 3.6266 1 221125_WJC_METTL3_EV_vs_WT_F07.15108.15108.2 0.067 17/32 K.K[136.11]ILDSVGIEADDDR[166.11]LNK[136.11].V sp|P05387|RLA2_HUMAN 1 1926.0268 1.4 102040 15108 2 1926.031073 964.0207 60S acidic ribosomal protein P2 OS=Homo sapiens OX=9606 GN=RPLP2 PE=1 SV=1 4.36 2629.4 - 476314 - - - 2.1973 - 3.754 0.664 - 584.9 1 2 1 0.0042 17 0 0 0 8.50E+06 6.08E+06 - - - 7.1962 1 221125_WJC_METTL3_EV_vs_WT_F07.15113.15113.3 1.69E-12 17/68 Y.HNLLEGGQEDFESSGAGK.L "sp|P35527|K1C9_HUMAN,tr|K7EQQ3|K7EQQ3_HUMAN" 2 1873.8442 427.04 102043 15113 3 1873.844881 625.622 "Keratin, type I cytoskeletal 9 OS=Homo sapiens OX=9606 GN=KRT9 PE=1 SV=3" 4.4 2630.1 - 4.06E+06 - - - 0.3447 - 3.621 0.624 - 575.4 1 1 0 0.0006 18 0 0 0 1.36E+08 3.18E+05 - - - 8.7009 0.9994 221125_WJC_METTL3_EV_vs_WT_F07.15114.15114.3 0.00239 Sep-52 K.ENYEKDEDFLSSTR.N "sp|O75970|MPDZ_HUMAN,tr|F5H1U9|F5H1U9_HUMAN" 2 1731.7588 1.96 102044 15114 3 1731.755156 578.2602 Multiple PDZ domain protein OS=Homo sapiens OX=9606 GN=MPDZ PE=1 SV=2 4.18 2630.1 - 723904 - - - -2.0892 - 1.835 0.488 - 91.3 1 2 1 -0.0036 14 0 0 0 1.28E+07 6.53E+06 - - - 5.593 0.7878 221125_WJC_METTL3_EV_vs_WT_F07.15117.15117.3 0.00928 Oct-60 R.R[166.11]K[136.11]TDFFIGGEEGMAEK[136.11].L "sp|Q9Y266|NUDC_HUMAN,tr|A0A0A0MSU9|A0A0A0MSU9_HUMAN" 2 1839.9036 2.31 102047 15117 3 1839.893383 614.3085 Nuclear migration protein nudC OS=Homo sapiens OX=9606 GN=NUDC PE=1 SV=1 4.87 2630.5 - 648624 - - - -5.528 - 1.789 0.238 - 97.9 1 2 1 -0.0102 16 0 0 0 2.59E+07 1.12E+07 - - - 2.6831 1 221125_WJC_METTL3_EV_vs_WT_F07.15121.15121.2 1.32E-06 13/32 K.GC[160.03]TSQEGGTTPTFPIQK[136.11].Q "sp|Q8IX18|DHX40_HUMAN,tr|J3KS08|J3KS08_HUMAN,tr|J3KSX9|J3KSX9_HUMAN,tr|J3KSW6|J3KSW6_HUMAN" 4 1815.8553 0.87 102051 15121 2 1815.854994 908.9349 Probable ATP-dependent RNA helicase DHX40 OS=Homo sapiens OX=9606 GN=DHX40 PE=1 SV=2 5.99 2631 - 286602 - - - -0.1487 - 2.751 0.642 - 376.9 1 2 0 -0.0003 17 0 0 0 4.81E+06 5.54E+06 - - - 6.2707 1 221125_WJC_METTL3_EV_vs_WT_F07.15123.15123.2 8.46E-09 Nov-32 K.GC[160.03]TSQEGGTTPTFPIQK.Q "sp|Q8IX18|DHX40_HUMAN,tr|J3KS08|J3KS08_HUMAN,tr|J3KSX9|J3KSX9_HUMAN,tr|J3KSW6|J3KSW6_HUMAN" 4 1807.8411 0.87 102053 15123 2 1807.840288 904.9278 Probable ATP-dependent RNA helicase DHX40 OS=Homo sapiens OX=9606 GN=DHX40 PE=1 SV=2 5.99 2631.3 - 189408 - - - -0.4292 - 2.303 0.642 - 257.7 1 2 0 -0.0008 17 0 0 0 4.81E+06 5.54E+06 - - - 5.8335 1 221125_WJC_METTL3_EV_vs_WT_F07.15125.15125.3 4.59E-06 16/56 K.THINIVVIGHVDSGK[136.11].S "sp|Q05639|EF1A2_HUMAN,sp|P68104|EF1A1_HUMAN,sp|Q5VTE0|EF1A3_HUMAN,tr|A0A2R8Y488|A0A2R8Y488_HUMAN,tr|A0A2R8YDN5|A0A2R8YDN5_HUMAN,tr|A0A7I2V659|A0A7I2V659_HUMAN,tr|A0A7I2V3H3|A0A7I2V3H3_HUMAN,tr|Q5JR01|Q5JR01_HUMAN,tr|A0A2U3TZH3|A0A2U3TZH3_HUMAN,tr|A0A7I2V5N4|A0A7I2V5N4_HUMAN,tr|A0A087WVQ9|A0A087WVQ9_HUMAN,tr|A6PW80|A6PW80_HUMAN,tr|A0A087WV01|A0A087WV01_HUMAN,tr|A0A2R8Y660|A0A2R8Y660_HUMAN,tr|A0A6Q8PFK6|A0A6Q8PFK6_HUMAN" 15 1595.8875 0.38 102054 15125 3 1595.88673 532.9698 Elongation factor 1-alpha 2 OS=Homo sapiens OX=9606 GN=EEF1A2 PE=1 SV=1 6.61 2631.5 - 2.63E+06 - - - -0.4762 - 3.435 0.611 - 465.5 1 2 0 -0.0008 15 0 0 0 4.92E+08 1.30E+09 - - - 8.5718 1 221125_WJC_METTL3_EV_vs_WT_F07.15127.15127.3 0.000374 Dec-64 R.NQELSQSVSSTTRPLLR.Q "sp|P82094|TMF1_HUMAN,tr|A0A2R8Y7M0|A0A2R8Y7M0_HUMAN" 2 1915.0123 1.59 102055 15127 3 1915.013327 639.3447 TATA element modulatory factor OS=Homo sapiens OX=9606 GN=TMF1 PE=1 SV=2 9.6 2631.7 - 6.07E+06 - - - 0.5347 - 2.577 0.45 - 165.7 1 2 0 0.001 17 0 0 0 1.46E+08 9.14E+07 - - - 5.9482 1 221125_WJC_METTL3_EV_vs_WT_F07.15128.15128.4 6.00E-07 20/84 R.VLSAPPHFHFGQTNR.T sp|P26641|EF1G_HUMAN 1 1706.8641 0.96 102056 15128 4 1706.865897 427.7233 Elongation factor 1-gamma OS=Homo sapiens OX=9606 GN=EEF1G PE=1 SV=3 9.73 2631.8 - 1.74E+06 - - - 1.0393 - 3.444 0.489 - 497.6 1 2 0 0.0018 15 0 0 0 2.25E+07 2.34E+07 - - - 3.9242 0.9991 221125_WJC_METTL3_EV_vs_WT_F07.15130.15130.3 0.00469 14/56 R.VKEDDLDVVLSPQRR.S "sp|Q9NRA8|4ET_HUMAN,tr|B1AKL5|B1AKL5_HUMAN,tr|B1AKL4|B1AKL4_HUMAN" 3 1767.9479 1.13 102058 15130 3 1767.948919 590.3232 Eukaryotic translation initiation factor 4E transporter OS=Homo sapiens OX=9606 GN=EIF4ENIF1 PE=1 SV=2 4.68 2632 - 719536 - - - 0.5696 - 2.061 0.369 - 181.4 1 2 1 0.001 15 0 0 0 1.41E+07 1.24E+07 - - - 4.5408 0.9998 221125_WJC_METTL3_EV_vs_WT_F07.15131.15131.3 0.00535 13/36 R.HTHQLYNFLR[166.11].F "sp|Q8WV92|MITD1_HUMAN,tr|H7C3Q6|H7C3Q6_HUMAN" 2 1337.6868 1.07 102059 15131 3 1337.686358 446.9029 MIT domain-containing protein 1 OS=Homo sapiens OX=9606 GN=MITD1 PE=1 SV=1 8.76 2632.1 - 565743 - - - -0.3484 - 2.431 0.323 - 354.1 1 2 0 -0.0005 10 0 0 0 1.16E+07 1.09E+07 - - - 4.7352 0.9983 221125_WJC_METTL3_EV_vs_WT_F07.15132.15132.3 0.00183 Nov-36 K.KKWDLSELPK.F "sp|Q92841|DDX17_HUMAN,tr|A0A5H1ZRQ2|A0A5H1ZRQ2_HUMAN,tr|A0A1X7SBZ2|A0A1X7SBZ2_HUMAN" 3 1242.6972 0.99 102060 15132 3 1242.697301 415.2397 Probable ATP-dependent RNA helicase DDX17 OS=Homo sapiens OX=9606 GN=DDX17 PE=1 SV=2 8.5 2632.3 - 425204 - - - 0.0628 - 1.908 0.324 - 178 1 2 1 0.0001 10 0 0 0 2.06E+07 2.08E+07 - - - 4.039 1 221125_WJC_METTL3_EV_vs_WT_F07.15137.15137.3 8.20E-06 19/56 R.VLSAPPHFHFGQTNR.T sp|P26641|EF1G_HUMAN 1 1706.8641 0.78 102063 15137 3 1706.863246 569.962 Elongation factor 1-gamma OS=Homo sapiens OX=9606 GN=EEF1G PE=1 SV=3 9.73 2632.9 - 852816 - - - -0.5138 - 3.116 0.489 - 495.8 1 2 0 -0.0009 15 0 0 0 1.94E+07 2.49E+07 - - - 6.9573 1 221125_WJC_METTL3_EV_vs_WT_F07.15138.15138.4 0.000115 17/90 K.YVLEAHGLKPVILKPK.E "sp|P42357|HUTH_HUMAN,tr|F8VNX0|F8VNX0_HUMAN" 2 1804.0975 999 102064 15138 4 1804.096895 452.0316 Histidine ammonia-lyase OS=Homo sapiens OX=9606 GN=HAL PE=1 SV=1 9.53 2633.1 - 950842 - - - -0.3226 - 2.971 0.507 - 121.1 1 2 0 -0.0006 16 0 0 0 1.08E+07 0.00E+00 - - - 4.0223 1 221125_WJC_METTL3_EV_vs_WT_F07.15139.15139.3 4.04E-06 19/64 K.LQENLQQLQHSTNQLAK.E "sp|Q86Y82|STX12_HUMAN,tr|B1AJQ6|B1AJQ6_HUMAN" 2 1992.0389 1.29 102065 15139 3 1992.035817 665.0202 Syntaxin-12 OS=Homo sapiens OX=9606 GN=STX12 PE=1 SV=1 6.75 2633.2 - 843166 - - - -1.5236 - 3.511 0.454 - 523.6 1 2 0 -0.003 17 0 0 0 5.02E+07 3.89E+07 - - - 6.7736 1 221125_WJC_METTL3_EV_vs_WT_F07.15140.15140.3 0.00189 19/60 R.SEVLHQVFISNC[160.03]DSSK[136.11].T "sp|Q86SF2|GALT7_HUMAN,tr|H0YAH3|H0YAH3_HUMAN" 2 1856.8818 1.36 102066 15140 3 1856.881888 619.9679 N-acetylgalactosaminyltransferase 7 OS=Homo sapiens OX=9606 GN=GALNT7 PE=1 SV=1 5.3 2633.3 - 565833 - - - 0.0404 - 3.352 0.502 - 550.4 1 2 0 0.0001 16 0 0 0 6.59E+07 4.84E+07 - - - 7.2403 0.9999 221125_WJC_METTL3_EV_vs_WT_F07.15141.15141.3 5.44E-06 15/64 R.AQVQEFC[160.03]DYGTK[136.11]EEC[160.03]MK[136.11].A "sp|Q86U44|MTA70_HUMAN,tr|H0YFV6|H0YFV6_HUMAN" 2 2137.909 0 102067 15141 3 2137.910044 713.6436 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 4.41 2633.4 - 509801 - - - 0.5056 - 2.867 0.598 - 219.8 1 2 1 0.0011 17 0 0 0 6.76E+04 1.56E+07 - - - 7.8677 0.9996 221125_WJC_METTL3_EV_vs_WT_F07.15143.15143.4 0.0607 Dec-66 K.DSEKEFHVLPYR.V sp|Q5SWX8|ODR4_HUMAN 1 1518.7467 1.28 102069 15143 4 1518.745707 380.6939 Protein odr-4 homolog OS=Homo sapiens OX=9606 GN=ODR4 PE=1 SV=1 5.45 2633.7 - 251324 - - - -0.6492 - 2.051 0.417 - 139.2 1 2 1 -0.001 12 0 0 0 1.52E+07 1.18E+07 - - - 3.1271 1 221125_WJC_METTL3_EV_vs_WT_F07.15146.15146.3 6.18E-07 17/64 K.LQENLQQLQHSTNQLAK[136.11].E "sp|Q86Y82|STX12_HUMAN,tr|B1AJQ6|B1AJQ6_HUMAN" 2 2000.0531 1.41 102070 15146 3 2000.052267 667.6916 Syntaxin-12 OS=Homo sapiens OX=9606 GN=STX12 PE=1 SV=1 6.75 2634.1 - 1.79E+06 - - - -0.3925 - 3.558 0.511 - 373.1 1 2 0 -0.0008 17 0 0 0 5.51E+07 3.89E+07 - - - 7.4433 0.9998 221125_WJC_METTL3_EV_vs_WT_F07.15147.15147.3 0.0315 15/36 K.K[136.11]K[136.11]WDLSELPK[136.11].F "sp|Q92841|DDX17_HUMAN,tr|A0A5H1ZRQ2|A0A5H1ZRQ2_HUMAN,tr|A0A1X7SBZ2|A0A1X7SBZ2_HUMAN" 3 1266.7398 0.99 102071 15147 3 1266.740571 423.2539 Probable ATP-dependent RNA helicase DDX17 OS=Homo sapiens OX=9606 GN=DDX17 PE=1 SV=2 8.5 2634.2 - 1.25E+06 - - - 0.5905 - 2.681 0.4 - 322.8 1 2 1 0.0007 10 0 0 0 2.06E+07 2.08E+07 - - - 5.8795 1 221125_WJC_METTL3_EV_vs_WT_F07.15148.15148.3 2.36E-09 14/60 R.SEVLHQVFISNC[160.03]DSSK.T "sp|Q86SF2|GALT7_HUMAN,tr|H0YAH3|H0YAH3_HUMAN" 2 1848.8676 1.33 102072 15148 3 1848.870808 617.2965 N-acetylgalactosaminyltransferase 7 OS=Homo sapiens OX=9606 GN=GALNT7 PE=1 SV=1 5.3 2634.3 - 1.31E+06 - - - 1.7281 - 2.815 0.664 - 281.8 1 2 0 0.0032 16 0 0 0 6.41E+07 4.83E+07 - - - 8.5976 0.9997 221125_WJC_METTL3_EV_vs_WT_F07.15149.15149.4 0.00173 21/96 K.SIQEIQELDK[136.11]DDESLR[166.11]K[136.11].Y "sp|P52565|GDIR1_HUMAN,tr|J3KS60|J3KS60_HUMAN,tr|J3KRY1|J3KRY1_HUMAN,tr|J3KRE2|J3KRE2_HUMAN,tr|J3QQX2|J3QQX2_HUMAN,tr|J3KTF8|J3KTF8_HUMAN" 6 2071.0643 2.23 102073 15149 4 2071.06819 518.7734 Rho GDP-dissociation inhibitor 1 OS=Homo sapiens OX=9606 GN=ARHGDIA PE=1 SV=3 4.3 2634.4 - 1.17E+06 - - - 1.8551 - 3.608 0.442 - 242.4 1 2 1 0.0038 17 0 0 0 3.23E+07 1.45E+07 - - - 3.5176 0.988 221125_WJC_METTL3_EV_vs_WT_F07.15150.15150.4 0.0195 14/96 K.SIQEIQELDKDDESLRK.Y "sp|P52565|GDIR1_HUMAN,tr|J3KS60|J3KS60_HUMAN,tr|J3KRY1|J3KRY1_HUMAN,tr|J3KRE2|J3KRE2_HUMAN,tr|J3QQX2|J3QQX2_HUMAN,tr|J3KTF8|J3KTF8_HUMAN" 6 2045.0277 2.25 102074 15150 4 2045.028991 512.2642 Rho GDP-dissociation inhibitor 1 OS=Homo sapiens OX=9606 GN=ARHGDIA PE=1 SV=3 4.3 2634.4 - 981315 - - - 0.642 - 1.942 0.247 - 91 1 2 1 0.0013 17 0 0 0 3.32E+07 1.48E+07 - - - 1.606 1 221125_WJC_METTL3_EV_vs_WT_F07.15151.15151.3 2.21E-10 20/84 K.VHELQGNAPSDPDAVSAEEALK.Y "sp|O95163|ELP1_HUMAN,tr|A0A6Q8PFB7|A0A6Q8PFB7_HUMAN,tr|A0A6Q8PFH9|A0A6Q8PFH9_HUMAN,tr|A0A6Q8PH48|A0A6Q8PH48_HUMAN,tr|A0A6Q8PHC9|A0A6Q8PHC9_HUMAN,tr|A0A6Q8PHI5|A0A6Q8PHI5_HUMAN,tr|A0A6Q8PF66|A0A6Q8PF66_HUMAN,tr|A0A6Q8PGW3|A0A6Q8PGW3_HUMAN,tr|A0A6Q8PG86|A0A6Q8PG86_HUMAN,tr|A0A6Q8PEX6|A0A6Q8PEX6_HUMAN,tr|F5H2T0|F5H2T0_HUMAN,tr|A0A6Q8PHF4|A0A6Q8PHF4_HUMAN,tr|A0A6Q8PFN8|A0A6Q8PFN8_HUMAN" 13 2276.0921 0.76 102075 15151 3 2276.093672 759.7046 Elongator complex protein 1 OS=Homo sapiens OX=9606 GN=ELP1 PE=1 SV=3 4.17 2634.6 - 957269 - - - 0.7038 - 3.949 0.628 - 387 1 2 0 0.0016 22 0 0 0 8.69E+06 1.14E+07 - - - 8.7974 1 221125_WJC_METTL3_EV_vs_WT_F07.15153.15153.2 4.24E-18 20/34 Y.HNLLEGGQEDFESSGAGK.L "sp|P35527|K1C9_HUMAN,tr|K7EQQ3|K7EQQ3_HUMAN" 2 1873.8442 999 102077 15153 2 1873.839042 937.9294 "Keratin, type I cytoskeletal 9 OS=Homo sapiens OX=9606 GN=KRT9 PE=1 SV=3" 4.4 2634.8 - 494202 - - - -2.7713 - 4.165 0.781 - 1095.5 1 1 0 -0.0052 18 0 0 0 4.74E+06 0.00E+00 - - - 8.3155 1 221125_WJC_METTL3_EV_vs_WT_F07.15159.15159.3 5.84E-07 16/52 K.SQIHDIVLVGGSTR.L "sp|P11142|HSP7C_HUMAN,tr|E9PNE6|E9PNE6_HUMAN,tr|A8K7Q2|A8K7Q2_HUMAN,tr|E9PKE3|E9PKE3_HUMAN,tr|E9PN89|E9PN89_HUMAN" 5 1480.7998 0.12 102081 15159 3 1480.802666 494.6072 Heat shock cognate 71 kDa protein OS=Homo sapiens OX=9606 GN=HSPA8 PE=1 SV=1 6.46 2635.7 - 1.91E+06 - - - 1.9415 - 2.931 0.514 - 297.8 1 2 0 0.0029 14 0 0 0 1.98E+07 1.65E+08 - - - 7.1276 0.9997 221125_WJC_METTL3_EV_vs_WT_F07.15160.15160.3 0.000451 22/68 R.ISC[160.03]YEASYQPLDPDKC[160.03]DR.D "sp|Q16875|F263_HUMAN,tr|A0A1W2PR17|A0A1W2PR17_HUMAN,tr|Q5W015|Q5W015_HUMAN,tr|F2Z2I2|F2Z2I2_HUMAN,tr|Q5VX20|Q5VX20_HUMAN" 5 2215.9514 5.06 102082 15160 3 2215.958482 739.6577 "6-phosphofructo-2-kinase\fructose-2,6-bisphosphatase 3 OS=Homo sapiens OX=9606 GN=PFKFB3 PE=1 SV=1" 4.23 2635.8 - 1.75E+06 - - - 3.1873 - 3.89 0.528 - 462.9 1 2 1 0.0071 18 0 0 0 4.85E+07 9.58E+06 - - - 7.8073 0.9979 221125_WJC_METTL3_EV_vs_WT_F07.15162.15162.4 0.0016 Nov-66 K.DSEK[136.11]EFHVLPYR[166.11].V sp|Q5SWX8|ODR4_HUMAN 1 1536.7692 1.28 102084 15162 4 1536.770175 385.1996 Protein odr-4 homolog OS=Homo sapiens OX=9606 GN=ODR4 PE=1 SV=1 5.45 2636 - 789915 - - - 0.6585 - 1.902 0.33 - 116.7 1 2 1 0.001 12 0 0 0 1.52E+07 1.18E+07 - - - 2.3413 0.9999 221125_WJC_METTL3_EV_vs_WT_F07.15163.15163.3 1.71E-06 19/64 K.SIQEIQELDK[136.11]DDESLR[166.11]K[136.11].Y "sp|P52565|GDIR1_HUMAN,tr|J3KS60|J3KS60_HUMAN,tr|J3KRY1|J3KRY1_HUMAN,tr|J3KRE2|J3KRE2_HUMAN,tr|J3QQX2|J3QQX2_HUMAN,tr|J3KTF8|J3KTF8_HUMAN" 6 2071.0643 4.98 102085 15163 3 2071.068906 691.3621 Rho GDP-dissociation inhibitor 1 OS=Homo sapiens OX=9606 GN=ARHGDIA PE=1 SV=3 4.3 2636.1 - 608866 - - - 2.2008 - 3.799 0.509 - 322.3 1 2 1 0.0046 17 0 0 0 2.94E+07 5.90E+06 - - - 7.5855 0.9999 221125_WJC_METTL3_EV_vs_WT_F07.15169.15169.3 0.000159 13/64 R.NQELSQSVSSTTR[166.11]PLLR[166.11].Q "sp|P82094|TMF1_HUMAN,tr|A0A2R8Y7M0|A0A2R8Y7M0_HUMAN" 2 1935.0288 1.59 102089 15169 3 1935.031589 646.0169 TATA element modulatory factor OS=Homo sapiens OX=9606 GN=TMF1 PE=1 SV=2 9.6 2636.8 - 4.33E+06 - - - 1.4191 - 2.871 0.409 - 227.5 1 2 0 0.0027 17 0 0 0 1.45E+08 9.11E+07 - - - 5.7636 1 221125_WJC_METTL3_EV_vs_WT_F07.15172.15172.3 0.00171 16/56 K.KLEEEQIILEDQNC[160.03]K.L sp|P35579|MYH9_HUMAN 1 1887.9248 1.17 102092 15172 3 1887.926447 630.3155 Myosin-9 OS=Homo sapiens OX=9606 GN=MYH9 PE=1 SV=4 4.25 2637 - 821309 - - - 0.8756 - 3.283 0.456 - 492.1 1 2 0 0.0017 15 0 0 0 5.33E+07 4.54E+07 - - - 6.7254 0.9998 221125_WJC_METTL3_EV_vs_WT_F07.15173.15173.3 0.000107 13/36 R.HTHQLYNFLR.F "sp|Q8WV92|MITD1_HUMAN,tr|H7C3Q6|H7C3Q6_HUMAN" 2 1327.6786 1.07 102093 15173 3 1327.679837 443.5668 MIT domain-containing protein 1 OS=Homo sapiens OX=9606 GN=MITD1 PE=1 SV=1 8.76 2637.1 - 724068 - - - 0.9663 - 2.418 0.318 - 411 1 2 0 0.0013 10 0 0 0 1.16E+07 1.09E+07 - - - 4.6636 0.9978 221125_WJC_METTL3_EV_vs_WT_F07.15176.15176.3 2.76E-07 13/84 Y.VLTGTEQGMTETFGTTC[160.03]HGAGR.A sp|Q9Y3I0|RTCB_HUMAN 1 2310.0369 1.83 102096 15176 3 2310.037529 771.0196 RNA-splicing ligase RtcB homolog OS=Homo sapiens OX=9606 GN=RTCB PE=1 SV=1 5.4 2637.5 - 420544 - - - 0.2809 - 2.63 0.55 - 144.4 1 1 0 0.0006 22 0 0 0 5.36E+06 2.92E+06 - - - 6.9643 1 221125_WJC_METTL3_EV_vs_WT_F07.15178.15178.2 7.48E-10 16/30 R.SEVLHQVFISNC[160.03]DSSK.T "sp|Q86SF2|GALT7_HUMAN,tr|H0YAH3|H0YAH3_HUMAN" 2 1848.8676 2.14 102098 15178 2 1848.873708 925.4411 N-acetylgalactosaminyltransferase 7 OS=Homo sapiens OX=9606 GN=GALNT7 PE=1 SV=1 5.3 2637.8 - 173882 - - - 3.2966 - 3.298 0.698 - 1121.8 1 2 0 0.0061 16 0 0 0 2.06E+06 9.63E+05 - - - 7.1283 0.9997 221125_WJC_METTL3_EV_vs_WT_F07.15181.15181.3 4.88E-07 18/44 K.DSEK[136.11]EFHVLPYR[166.11].V sp|Q5SWX8|ODR4_HUMAN 1 1536.7692 1.37 102099 15181 3 1536.773655 513.2637 Protein odr-4 homolog OS=Homo sapiens OX=9606 GN=ODR4 PE=1 SV=1 5.45 2638.2 - 1.81E+06 - - - 2.923 - 2.919 0.528 - 556.3 1 2 1 0.0045 12 0 0 0 3.84E+07 2.81E+07 - - - 7.3948 1 221125_WJC_METTL3_EV_vs_WT_F07.15183.15183.3 1.66E-05 15/56 K.K[136.11]LEEEQIILEDQNC[160.03]K[136.11].L sp|P35579|MYH9_HUMAN 1 1903.9532 1.16 102101 15183 3 1903.956349 635.6583 Myosin-9 OS=Homo sapiens OX=9606 GN=MYH9 PE=1 SV=4 4.25 2638.3 - 2.10E+06 - - - 1.6571 - 3.282 0.541 - 426.4 1 2 0 0.0032 15 0 0 0 5.28E+07 4.54E+07 - - - 7.6719 0.9971 221125_WJC_METTL3_EV_vs_WT_F07.15184.15184.3 6.52E-08 13/44 C.HNC[160.03]AVEFNFGQK[136.11].E "sp|Q00839|HNRPU_HUMAN,tr|A0A1W2PQL0|A0A1W2PQL0_HUMAN,tr|A0A1W2PPL4|A0A1W2PPL4_HUMAN,tr|A0A1W2PQ74|A0A1W2PQ74_HUMAN,tr|Q5RI18|Q5RI18_HUMAN,tr|A0A1W2PP35|A0A1W2PP35_HUMAN,tr|A0A1W2PPS1|A0A1W2PPS1_HUMAN,tr|A0A1W2PRZ7|A0A1W2PRZ7_HUMAN,tr|A0A1W2PPH7|A0A1W2PPH7_HUMAN,tr|A0A1W2PP34|A0A1W2PP34_HUMAN,tr|A0A1X7SBS1|A0A1X7SBS1_HUMAN" 11 1457.6601 1.03 102102 15184 3 1457.662795 486.894 Heterogeneous nuclear ribonucleoprotein U OS=Homo sapiens OX=9606 GN=HNRNPU PE=1 SV=6 6.74 2638.5 - 879167 - - - 1.8262 - 2.608 0.557 - 152 1 1 0 0.0027 12 0 0 0 1.06E+07 1.03E+07 - - - 7.4063 1 221125_WJC_METTL3_EV_vs_WT_F07.15185.15185.3 2.98E-10 17/44 C.HNC[160.03]AVEFNFGQK.E "sp|Q00839|HNRPU_HUMAN,tr|A0A1W2PQL0|A0A1W2PQL0_HUMAN,tr|A0A1W2PPL4|A0A1W2PPL4_HUMAN,tr|A0A1W2PQ74|A0A1W2PQ74_HUMAN,tr|Q5RI18|Q5RI18_HUMAN,tr|A0A1W2PP35|A0A1W2PP35_HUMAN,tr|A0A1W2PPS1|A0A1W2PPS1_HUMAN,tr|A0A1W2PRZ7|A0A1W2PRZ7_HUMAN,tr|A0A1W2PPH7|A0A1W2PPH7_HUMAN,tr|A0A1W2PP34|A0A1W2PP34_HUMAN,tr|A0A1X7SBS1|A0A1X7SBS1_HUMAN" 11 1449.6459 1.03 102103 15185 3 1449.648924 484.2226 Heterogeneous nuclear ribonucleoprotein U OS=Homo sapiens OX=9606 GN=HNRNPU PE=1 SV=6 6.74 2638.6 - 866371 - - - 2.0633 - 3.085 0.669 - 510.8 1 1 0 0.003 12 0 0 0 1.06E+07 1.03E+07 - - - 9.1205 0.9999 221125_WJC_METTL3_EV_vs_WT_F07.15193.15193.3 3.17E-06 19/44 K.DSEKEFHVLPYR.V sp|Q5SWX8|ODR4_HUMAN 1 1518.7467 1.37 102110 15193 3 1518.75011 507.2562 Protein odr-4 homolog OS=Homo sapiens OX=9606 GN=ODR4 PE=1 SV=1 5.45 2639.6 - 2.24E+06 - - - 2.2499 - 3.263 0.583 - 662.4 1 2 1 0.0034 12 0 0 0 3.87E+07 2.84E+07 - - - 8.317 1 221125_WJC_METTL3_EV_vs_WT_F07.15197.15197.3 2.27E-12 19/76 R.ETDC[160.03]GVHINAGPEIGVASTK.A "sp|Q06210|GFPT1_HUMAN,sp|O94808|GFPT2_HUMAN,tr|A0A6I8PRN4|A0A6I8PRN4_HUMAN,tr|A0A6I8PTT9|A0A6I8PTT9_HUMAN" 4 2053.9739 1.16 102113 15197 3 2053.976254 685.6652 Glutamine--fructose-6-phosphate aminotransferase [isomerizing] 1 OS=Homo sapiens OX=9606 GN=GFPT1 PE=1 SV=3 4.65 2640 - 1.02E+06 - - - 1.1612 - 3.48 0.616 - 381.2 1 2 0 0.0024 20 0 0 0 6.30E+07 5.45E+07 - - - 8.4325 1 221125_WJC_METTL3_EV_vs_WT_F07.15198.15198.3 5.21E-13 16/68 K.KLDVEEPDSANSSFYSTR.S "sp|Q14980|NUMA1_HUMAN,tr|A0A087WY61|A0A087WY61_HUMAN,tr|H0YFY6|H0YFY6_HUMAN" 3 2043.9385 2.5 102114 15198 3 2043.936589 682.3201 Nuclear mitotic apparatus protein 1 OS=Homo sapiens OX=9606 GN=NUMA1 PE=1 SV=2 4.32 2640.1 - 961628 - - - -0.9491 - 3.652 0.695 - 446.1 1 2 0 -0.0019 18 0 0 0 1.02E+07 4.08E+06 - - - 9.5134 1 221125_WJC_METTL3_EV_vs_WT_F07.15199.15199.3 1.80E-07 23/68 R.ISC[160.03]YEASYQPLDPDK[136.11]C[160.03]DR[166.11].D "sp|Q16875|F263_HUMAN,tr|A0A1W2PR17|A0A1W2PR17_HUMAN,tr|Q5W015|Q5W015_HUMAN,tr|F2Z2I2|F2Z2I2_HUMAN,tr|Q5VX20|Q5VX20_HUMAN" 5 2233.9739 4.95 102115 15199 3 2233.971546 745.6652 "6-phosphofructo-2-kinase\fructose-2,6-bisphosphatase 3 OS=Homo sapiens OX=9606 GN=PFKFB3 PE=1 SV=1" 4.23 2640.2 - 936228 - - - -1.0488 - 3.636 0.603 - 494.5 1 2 1 -0.0023 18 0 0 0 4.74E+07 9.58E+06 - - - 8.4766 0.9999 221125_WJC_METTL3_EV_vs_WT_F07.15200.15200.3 0.000118 15/68 K.SQPNLDTC[160.03]AFHEQPELQK.K "sp|P01037|CYTN_HUMAN,sp|P09228|CYTT_HUMAN,sp|P01036|CYTS_HUMAN" 3 2140.9848 19.49 102116 15200 3 2140.991476 714.6689 Cystatin-SN OS=Homo sapiens OX=9606 GN=CST1 PE=1 SV=3 4.65 2640.4 - 772401 - - - 3.1331 - 3.215 0.495 - 220.2 1 2 0 0.0067 18 0 0 0 3.18E+07 1.63E+06 - - - 6.9649 0.9999 221125_WJC_METTL3_EV_vs_WT_F07.15201.15201.4 3.16E-09 18/102 K.SLK[136.11]EEDGEEIVTYDHLC[160.03]K[136.11].N "sp|Q8WUH1|CHUR_HUMAN,tr|H0YHA3|H0YHA3_HUMAN,tr|B4DL54|B4DL54_HUMAN,tr|A0A0C4DGJ7|A0A0C4DGJ7_HUMAN,tr|H0YID9|H0YID9_HUMAN" 5 2180.0278 1.35 102117 15201 4 2180.030963 546.0142 Protein Churchill OS=Homo sapiens OX=9606 GN=CHURC1 PE=1 SV=2 4.35 2640.5 - 758068 - - - 1.444 - 3.065 0.583 - 204.7 1 2 1 0.0031 18 0 0 0 1.93E+07 1.43E+07 - - - 4.6832 1 221125_WJC_METTL3_EV_vs_WT_F07.15206.15206.3 0.000459 15/60 R.QETSVVNYIDQRPAAK.K sp|Q9H813|PACC1_HUMAN 1 1817.9272 0.63 102122 15206 3 1817.928131 606.983 Proton-activated chloride channel OS=Homo sapiens OX=9606 GN=PACC1 PE=1 SV=1 6.07 2641.1 - 330382 - - - 0.5253 - 2.54 0.525 - 281 1 2 0 0.001 16 0 0 0 2.11E+06 3.32E+06 - - - 6.7848 0.9995 221125_WJC_METTL3_EV_vs_WT_F07.15207.15207.3 0.00298 Dec-60 R.QETSVVNYIDQR[166.11]PAAK[136.11].K sp|Q9H813|PACC1_HUMAN 1 1835.9496 0.63 102123 15207 3 1835.947649 612.9905 Proton-activated chloride channel OS=Homo sapiens OX=9606 GN=PACC1 PE=1 SV=1 6.07 2641.2 - 296813 - - - -1.0877 - 2.18 0.292 - 157.4 1 2 0 -0.002 16 0 0 0 2.11E+06 3.32E+06 - - - 3.7946 1 221125_WJC_METTL3_EV_vs_WT_F07.15210.15210.2 8.94E-09 13/30 R.SEVLHQVFISNC[160.03]DSSK[136.11].T "sp|Q86SF2|GALT7_HUMAN,tr|H0YAH3|H0YAH3_HUMAN" 2 1856.8818 2.14 102126 15210 2 1856.888567 929.4482 N-acetylgalactosaminyltransferase 7 OS=Homo sapiens OX=9606 GN=GALNT7 PE=1 SV=1 5.3 2641.6 - 107980 - - - 3.6373 - 2.813 0.669 - 516.7 1 2 0 0.0068 16 0 0 0 2.06E+06 9.63E+05 - - - 6.5229 1 221125_WJC_METTL3_EV_vs_WT_F07.15211.15211.2 1.08E-08 14/28 K.K[136.11]LEEEQIILEDQNC[160.03]K[136.11].L sp|P35579|MYH9_HUMAN 1 1903.9532 0.88 102127 15211 2 1903.952703 952.9839 Myosin-9 OS=Homo sapiens OX=9606 GN=MYH9 PE=1 SV=4 4.25 2641.8 - 102507 - - - -0.2579 - 3.045 0.684 - 787.1 1 2 0 -0.0005 15 0 0 0 1.27E+06 1.45E+06 - - - 6.8305 0.9997 221125_WJC_METTL3_EV_vs_WT_F07.15215.15215.4 2.38E-08 18/102 K.SLKEEDGEEIVTYDHLC[160.03]K.N "sp|Q8WUH1|CHUR_HUMAN,tr|H0YHA3|H0YHA3_HUMAN,tr|B4DL54|B4DL54_HUMAN,tr|A0A0C4DGJ7|A0A0C4DGJ7_HUMAN,tr|H0YID9|H0YID9_HUMAN" 5 2163.9994 1.32 102129 15215 4 2164.006796 542.0071 Protein Churchill OS=Homo sapiens OX=9606 GN=CHURC1 PE=1 SV=2 4.35 2642.2 - 1.80E+06 - - - 3.4108 - 3.446 0.578 - 224.5 1 2 1 0.0074 18 0 0 0 1.87E+07 1.42E+07 - - - 4.6787 0.9971 221125_WJC_METTL3_EV_vs_WT_F07.15218.15218.3 0.0215 Nov-44 R.DLDELSRYPEDK.L "sp|P43243|MATR3_HUMAN,tr|A8MXP9|A8MXP9_HUMAN,tr|D6R991|D6R991_HUMAN,tr|A0A0R4J2E8|A0A0R4J2E8_HUMAN,tr|D6REM6|D6REM6_HUMAN" 5 1478.6889 1.31 102132 15218 3 1478.691702 493.9036 Matrin-3 OS=Homo sapiens OX=9606 GN=MATR3 PE=1 SV=2 4.11 2642.5 - 1.01E+06 - - - 1.8929 - 2.112 0.313 - 115.8 1 2 1 0.0028 12 0 0 0 3.33E+07 2.53E+07 - - - 4.1012 1 221125_WJC_METTL3_EV_vs_WT_F07.15222.15222.3 2.14E-07 22/68 K.SLKEEDGEEIVTYDHLC[160.03]K.N "sp|Q8WUH1|CHUR_HUMAN,tr|H0YHA3|H0YHA3_HUMAN,tr|B4DL54|B4DL54_HUMAN,tr|A0A0C4DGJ7|A0A0C4DGJ7_HUMAN,tr|H0YID9|H0YID9_HUMAN" 5 2163.9994 0.67 102136 15222 3 2164.002975 722.3404 Protein Churchill OS=Homo sapiens OX=9606 GN=CHURC1 PE=1 SV=2 4.35 2642.9 - 581924 - - - 1.6451 - 4.227 0.639 - 700.6 1 2 1 0.0036 18 0 0 0 7.46E+06 1.12E+07 - - - 9.2527 0.9999 221125_WJC_METTL3_EV_vs_WT_F07.15223.15223.3 4.16E-06 20/72 R.DRAPQTLPSPEADALAGSK.H sp|P31274|HXC9_HUMAN 1 1922.9698 2.11 102137 15223 3 1922.970414 641.9972 Homeobox protein Hox-C9 OS=Homo sapiens OX=9606 GN=HOXC9 PE=1 SV=3 4.56 2643.1 - 459344 - - - 0.3349 - 3.299 0.51 - 504.5 1 2 1 0.0006 19 0 0 0 1.86E+07 8.78E+06 - - - 7.1583 0.9995 221125_WJC_METTL3_EV_vs_WT_F07.15227.15227.3 0.00126 13/40 R.RQHAEELLEWK.R "sp|Q5VT06|CE350_HUMAN,tr|H0Y7F7|H0Y7F7_HUMAN" 2 1437.7365 2.06 102141 15227 3 1437.742102 480.2528 Centrosome-associated protein 350 OS=Homo sapiens OX=9606 GN=CEP350 PE=1 SV=1 5.5 2643.6 - 225935 - - - 3.9228 - 2.801 0.369 - 300 1 2 0 0.0056 11 0 0 0 3.48E+06 1.69E+06 - - - 5.5784 1 221125_WJC_METTL3_EV_vs_WT_F07.15230.15230.2 9.21E-10 28-Dec K.KLEEEQIILEDQNC[160.03]K.L sp|P35579|MYH9_HUMAN 1 1887.9248 0.88 102144 15230 2 1887.9289 944.9697 Myosin-9 OS=Homo sapiens OX=9606 GN=MYH9 PE=1 SV=4 4.25 2644 - 146127 - - - 2.1749 - 2.956 0.604 - 433.9 1 2 0 0.0041 15 0 0 0 1.27E+06 1.45E+06 - - - 6.1655 0.9995 221125_WJC_METTL3_EV_vs_WT_F07.15233.15233.3 7.48E-05 Dec-44 R.DLDELSR[166.11]YPEDK[136.11].L "sp|P43243|MATR3_HUMAN,tr|A8MXP9|A8MXP9_HUMAN,tr|D6R991|D6R991_HUMAN,tr|A0A0R4J2E8|A0A0R4J2E8_HUMAN,tr|D6REM6|D6REM6_HUMAN" 5 1496.7114 1.34 102145 15233 3 1496.714803 499.9111 Matrin-3 OS=Homo sapiens OX=9606 GN=MATR3 PE=1 SV=2 4.11 2644.4 - 1.03E+06 - - - 2.2917 - 2.254 0.462 - 130.7 1 2 1 0.0034 12 0 0 0 3.28E+07 2.45E+07 - - - 5.9426 1 221125_WJC_METTL3_EV_vs_WT_F07.15234.15234.3 2.27E-07 14/60 K.HSLEEDEGSDFITENR.N sp|Q9NUQ3|TXLNG_HUMAN 1 1876.8075 1.37 102146 15234 3 1876.813127 626.6098 Gamma-taxilin OS=Homo sapiens OX=9606 GN=TXLNG PE=1 SV=2 4.08 2644.5 - 755162 - - - 2.9902 - 3.197 0.629 - 293.4 1 2 0 0.0056 16 0 0 0 1.74E+07 1.27E+07 - - - 8.5333 0.9999 221125_WJC_METTL3_EV_vs_WT_F07.15235.15235.3 5.31E-05 16/80 R.TVSPGSVSPIHGQGQVVENLK.A "sp|Q9NZM3|ITSN2_HUMAN,tr|A0A087WVF7|A0A087WVF7_HUMAN" 2 2132.1226 2.88 102147 15235 3 2132.128131 711.7148 Intersectin-2 OS=Homo sapiens OX=9606 GN=ITSN2 PE=1 SV=3 6.41 2644.6 - 867176 - - - 2.6026 - 3.005 0.433 - 175.5 1 2 0 0.0056 21 0 0 0 1.17E+07 4.08E+06 - - - 6.0039 0.9983 221125_WJC_METTL3_EV_vs_WT_F07.15236.15236.4 0.0407 13/120 R.GGVGLTGRPPSGIRPLSGNIR.V "sp|Q96LB3|IFT74_HUMAN,tr|E5RJK3|E5RJK3_HUMAN,tr|E5RGX6|E5RGX6_HUMAN,tr|A0A3B3IT46|A0A3B3IT46_HUMAN,tr|E5RH29|E5RH29_HUMAN" 5 2060.1603 3.45 102148 15236 4 2060.1644 516.0474 Intraflagellar transport protein 74 homolog OS=Homo sapiens OX=9606 GN=IFT74 PE=1 SV=1 12.3 2644.7 - 479904 - - - 1.9877 - 2.012 0.294 - 70.6 1 2 0 0.0041 21 0 0 0 8.00E+06 2.32E+06 - - - 2.015 0.9988 221125_WJC_METTL3_EV_vs_WT_F07.15238.15238.3 0.00669 Dec-48 K.RPSRPINITSLVR.L sp|O75925|PIAS1_HUMAN 1 1507.8947 1.25 102150 15238 3 1507.896806 503.6388 E3 SUMO-protein ligase PIAS1 OS=Homo sapiens OX=9606 GN=PIAS1 PE=1 SV=2 12.3 2645 - 403306 - - - 1.4006 - 1.715 0.303 - 104.5 1 2 0 0.0021 13 0 0 0 1.20E+07 9.65E+06 - - - 3.3801 0.9971 221125_WJC_METTL3_EV_vs_WT_F07.15240.15240.3 0.000324 Sep-72 K.DC[160.03]GDDLSPIKPVPSGEGVK.A "sp|O95935|TBX18_HUMAN,tr|U3KQH2|U3KQH2_HUMAN,tr|U3KQ31|U3KQ31_HUMAN" 3 1968.9463 0.32 102152 15240 3 1968.955637 657.3227 T-box transcription factor TBX18 OS=Homo sapiens OX=9606 GN=TBX18 PE=1 SV=3 4.23 2645.3 - 229995 - - - 4.764 - 1.979 0.388 - 77.6 1 2 0 0.0094 19 0 0 0 4.41E+06 1.39E+07 - - - 4.5402 0.9984 221125_WJC_METTL3_EV_vs_WT_F07.15245.15245.3 0.000256 14/48 R.AKRPEVPFPEITR.M "sp|Q9NP66|HM20A_HUMAN,tr|H0YNS8|H0YNS8_HUMAN,tr|H0YMS9|H0YMS9_HUMAN,tr|H0YKM5|H0YKM5_HUMAN,tr|H0YK55|H0YK55_HUMAN" 5 1538.8569 2.8 102155 15245 3 1538.861438 513.9596 High mobility group protein 20A OS=Homo sapiens OX=9606 GN=HMG20A PE=1 SV=1 8.79 2645.9 - 610967 - - - 2.9411 - 2.282 0.403 - 227.4 1 2 1 0.0045 13 0 0 0 1.11E+07 3.97E+06 - - - 5.2688 0.998 221125_WJC_METTL3_EV_vs_WT_F07.15248.15248.3 0.00267 15/48 K.R[166.11]PSR[166.11]PINITSLVR[166.11].L sp|O75925|PIAS1_HUMAN 1 1537.9195 1.25 102158 15248 3 1537.923102 513.6471 E3 SUMO-protein ligase PIAS1 OS=Homo sapiens OX=9606 GN=PIAS1 PE=1 SV=2 12.3 2646.2 - 610967 - - - 2.3395 - 1.811 0.297 - 189.8 1 2 0 0.0036 13 0 0 0 1.20E+07 9.65E+06 - - - 3.4604 0.9998 221125_WJC_METTL3_EV_vs_WT_F07.15249.15249.3 3.34E-09 18/68 K.GKEDEGEEAASPMLQIQR.D "sp|Q14204|DYHC1_HUMAN,tr|A0A7P0T8N2|A0A7P0T8N2_HUMAN,tr|A0A7P0T9C4|A0A7P0T9C4_HUMAN,tr|A0A7P0TBJ7|A0A7P0TBJ7_HUMAN,tr|A0A804HHY6|A0A804HHY6_HUMAN,tr|A0A7P0T9K2|A0A7P0T9K2_HUMAN,tr|A0A7P0TB64|A0A7P0TB64_HUMAN,tr|A0A2R8Y706|A0A2R8Y706_HUMAN,tr|A0A7P0T916|A0A7P0T916_HUMAN,tr|A0A7P0TB75|A0A7P0TB75_HUMAN,tr|A0A7P0T8W5|A0A7P0T8W5_HUMAN,tr|A0A7P0TAF3|A0A7P0TAF3_HUMAN,tr|A0A7P0T9F1|A0A7P0T9F1_HUMAN,tr|A0A7P0TAW9|A0A7P0TAW9_HUMAN,tr|A0A2R8YGC7|A0A2R8YGC7_HUMAN,tr|A0A7P0TA13|A0A7P0TA13_HUMAN,tr|A0A7P0TAV5|A0A7P0TAV5_HUMAN,tr|A0A7P0T7V5|A0A7P0T7V5_HUMAN,tr|A0A7P0T9R4|A0A7P0T9R4_HUMAN,tr|A0A2R8Y5T0|A0A2R8Y5T0_HUMAN,tr|A0A7P0T990|A0A7P0T990_HUMAN,tr|A0A7P0T942|A0A7P0T942_HUMAN,tr|A0A2R8YFZ7|A0A2R8YFZ7_HUMAN,tr|A0A7P0T825|A0A7P0T825_HUMAN,tr|A0A2R8Y6H2|A0A2R8Y6H2_HUMAN,tr|A0A7P0TAM4|A0A7P0TAM4_HUMAN" 26 1986.9317 0.45 102159 15249 3 1986.931467 663.3178 Cytoplasmic dynein 1 heavy chain 1 OS=Homo sapiens OX=9606 GN=DYNC1H1 PE=1 SV=5 4.25 2646.3 - 532386 - - - -0.1022 - 3.4 0.406 - 358.8 1 2 1 -0.0002 18 0 0 0 7.15E+06 1.60E+07 - - - 6.1138 0.9996 221125_WJC_METTL3_EV_vs_WT_F07.15254.15254.2 2.74E-05 30-Oct K.GDNSSVSSLC[160.03]ISPDGK[136.11].M "sp|Q15061|WDR43_HUMAN,tr|C9JEE7|C9JEE7_HUMAN" 2 1629.7396 1.83 102164 15254 2 1629.744528 815.8771 WD repeat-containing protein 43 OS=Homo sapiens OX=9606 GN=WDR43 PE=1 SV=3 4.21 2647 - 157854 - - - 3.0453 - 2.187 0.61 - 281.1 1 2 0 0.005 16 0 0 0 5.69E+06 3.11E+06 - - - 5.4688 1 221125_WJC_METTL3_EV_vs_WT_F07.15257.15257.3 4.45E-14 18/48 L.C[160.03]HNC[160.03]AVEFNFGQK.E "sp|Q00839|HNRPU_HUMAN,tr|A0A1W2PQL0|A0A1W2PQL0_HUMAN,tr|A0A1W2PPL4|A0A1W2PPL4_HUMAN,tr|A0A1W2PQ74|A0A1W2PQ74_HUMAN,tr|Q5RI18|Q5RI18_HUMAN,tr|A0A1W2PP35|A0A1W2PP35_HUMAN,tr|A0A1W2PPS1|A0A1W2PPS1_HUMAN,tr|A0A1W2PRZ7|A0A1W2PRZ7_HUMAN,tr|A0A1W2PPH7|A0A1W2PPH7_HUMAN,tr|A0A1W2PP34|A0A1W2PP34_HUMAN,tr|A0A1X7SBS1|A0A1X7SBS1_HUMAN" 11 1609.6766 1.06 102165 15257 3 1609.680971 537.5661 Heterogeneous nuclear ribonucleoprotein U OS=Homo sapiens OX=9606 GN=HNRNPU PE=1 SV=6 6.73 2647.4 - 2.41E+06 - - - 2.7266 - 3.381 0.752 - 809.6 1 1 0 0.0044 13 0 0 0 9.13E+07 8.59E+07 - - - 10.2257 1 221125_WJC_METTL3_EV_vs_WT_F07.15258.15258.3 3.83E-12 16/48 L.C[160.03]HNC[160.03]AVEFNFGQK[136.11].E "sp|Q00839|HNRPU_HUMAN,tr|A0A1W2PQL0|A0A1W2PQL0_HUMAN,tr|A0A1W2PPL4|A0A1W2PPL4_HUMAN,tr|A0A1W2PQ74|A0A1W2PQ74_HUMAN,tr|Q5RI18|Q5RI18_HUMAN,tr|A0A1W2PP35|A0A1W2PP35_HUMAN,tr|A0A1W2PPS1|A0A1W2PPS1_HUMAN,tr|A0A1W2PRZ7|A0A1W2PRZ7_HUMAN,tr|A0A1W2PPH7|A0A1W2PPH7_HUMAN,tr|A0A1W2PP34|A0A1W2PP34_HUMAN,tr|A0A1X7SBS1|A0A1X7SBS1_HUMAN" 11 1617.6908 1.06 102166 15258 3 1617.694618 540.2375 Heterogeneous nuclear ribonucleoprotein U OS=Homo sapiens OX=9606 GN=HNRNPU PE=1 SV=6 6.73 2647.4 - 2.67E+06 - - - 2.3713 - 3.134 0.745 - 570.2 1 1 0 0.0038 13 0 0 0 9.13E+07 8.59E+07 - - - 9.9421 0.999 221125_WJC_METTL3_EV_vs_WT_F07.15263.15263.3 1.19E-07 Oct-64 K.TLEEEAKTHEAQIQEMR.Q sp|P35579|MYH9_HUMAN 1 2041.9739 0.08 102171 15263 3 2041.982446 681.6652 Myosin-9 OS=Homo sapiens OX=9606 GN=MYH9 PE=1 SV=4 4.64 2648 - 321401 - - - 4.2003 - 2.545 0.528 - 61.8 1 2 1 0.0086 17 0 0 0 2.35E+06 2.94E+07 - - - 6.7842 0.9962 221125_WJC_METTL3_EV_vs_WT_F07.15264.15264.4 0.0106 Nov-72 R.AKRPEVPFPEITR.M "sp|Q9NP66|HM20A_HUMAN,tr|H0YNS8|H0YNS8_HUMAN,tr|H0YMS9|H0YMS9_HUMAN,tr|H0YKM5|H0YKM5_HUMAN,tr|H0YK55|H0YK55_HUMAN" 5 1538.8569 3.52 102172 15264 4 1538.859918 385.7215 High mobility group protein 20A OS=Homo sapiens OX=9606 GN=HMG20A PE=1 SV=1 8.79 2648.1 - 264772 - - - 1.9534 - 1.878 0.322 - 93.7 1 2 1 0.003 13 0 0 0 5.17E+06 1.47E+06 - - - 2.2615 1 221125_WJC_METTL3_EV_vs_WT_F07.15268.15268.3 4.41E-11 17/72 K.LHISPSNMTNQNTPEYMEK.L sp|Q92769|HDAC2_HUMAN 1 2233.0144 1.72 102174 15268 3 2233.019094 745.3454 Histone deacetylase 2 OS=Homo sapiens OX=9606 GN=HDAC2 PE=1 SV=2 5.4 2648.7 - 2.76E+06 - - - 2.1231 - 3.669 0.689 - 319.6 1 2 0 0.0047 19 0 0 0 6.02E+07 3.51E+07 - - - 9.414 1 221125_WJC_METTL3_EV_vs_WT_F07.15269.15269.3 6.61E-09 25/76 R.DTTVISHSPNTSYDTALEAR.L "sp|Q4VCS5|AMOT_HUMAN,tr|A6NP16|A6NP16_HUMAN,tr|E7ERM3|E7ERM3_HUMAN" 3 2177.0237 3.31 102175 15269 3 2177.027882 726.6818 Angiomotin OS=Homo sapiens OX=9606 GN=AMOT PE=1 SV=1 4.54 2648.8 - 1.91E+06 - - - 1.9412 - 3.744 0.644 - 837.4 1 2 0 0.0042 20 0 0 0 3.95E+07 1.19E+07 - - - 8.9215 1 221125_WJC_METTL3_EV_vs_WT_F07.15270.15270.3 5.27E-07 Nov-60 K.HSLEEDEGSDFITENR[166.11].N sp|Q9NUQ3|TXLNG_HUMAN 1 1886.8158 1.4 102176 15270 3 1886.817652 629.9459 Gamma-taxilin OS=Homo sapiens OX=9606 GN=TXLNG PE=1 SV=2 4.08 2648.9 - 1.18E+06 - - - 0.9895 - 2.654 0.62 - 127.8 1 2 0 0.0019 16 0 0 0 1.77E+07 1.27E+07 - - - 7.9563 0.9999 221125_WJC_METTL3_EV_vs_WT_F07.15271.15271.4 2.04E-05 18/84 R.TLPHFIKDDYGPESR.G "sp|P24928|RPB1_HUMAN,tr|A0A6Q8PGB0|A0A6Q8PGB0_HUMAN" 2 1773.8686 1.67 102177 15271 4 1773.87233 444.4744 DNA-directed RNA polymerase II subunit RPB1 OS=Homo sapiens OX=9606 GN=POLR2A PE=1 SV=2 5.35 2649 - 970756 - - - 2.1033 - 3.157 0.569 - 221.9 1 2 1 0.0037 15 0 0 0 1.78E+07 1.06E+07 - - - 4.5889 0.9998 221125_WJC_METTL3_EV_vs_WT_F07.15273.15273.4 0.00762 Nov-78 R.KYFTC[160.03]DEGHGIFVR.Q "sp|Q14203|DCTN1_HUMAN,tr|C9JTE5|C9JTE5_HUMAN,tr|A0A804CDA6|A0A804CDA6_HUMAN,tr|C9JJN7|C9JJN7_HUMAN,tr|E7EX90|E7EX90_HUMAN,tr|C9JJD0|C9JJD0_HUMAN,tr|A0A7P0Z4C3|A0A7P0Z4C3_HUMAN,tr|Q6AWB1|Q6AWB1_HUMAN,tr|C9JZA4|C9JZA4_HUMAN,tr|E9PCY0|E9PCY0_HUMAN,tr|C9JKG6|C9JKG6_HUMAN" 11 1727.809 1.57 102179 15273 4 1727.810897 432.9595 Dynactin subunit 1 OS=Homo sapiens OX=9606 GN=DCTN1 PE=1 SV=3 6.74 2649.2 - 235653 - - - 1.1118 - 2.08 0.396 - 91.6 1 2 0 0.0019 14 0 0 0 1.68E+06 1.07E+06 - - - 2.9388 0.9995 221125_WJC_METTL3_EV_vs_WT_F07.15274.15274.3 0.000284 Oct-68 K.LK[136.11]SELVANNVTLPAGEQR[166.11].K "sp|P42166|LAP2A_HUMAN,sp|P42167|LAP2B_HUMAN,tr|G5E972|G5E972_HUMAN" 3 1956.0759 1.24 102180 15274 3 1956.077288 653.0326 "Lamina-associated polypeptide 2, isoform alpha OS=Homo sapiens OX=9606 GN=TMPO PE=1 SV=2" 6.14 2649.4 - 196995 - - - 0.7045 - 2.23 0.412 - 92.3 1 2 1 0.0014 18 0 0 0 4.11E+06 3.33E+06 - - - 5.1301 1 221125_WJC_METTL3_EV_vs_WT_F07.15276.15276.2 2.04E-13 14/24 L.C[160.03]HNC[160.03]AVEFNFGQK.E "sp|Q00839|HNRPU_HUMAN,tr|A0A1W2PQL0|A0A1W2PQL0_HUMAN,tr|A0A1W2PPL4|A0A1W2PPL4_HUMAN,tr|A0A1W2PQ74|A0A1W2PQ74_HUMAN,tr|Q5RI18|Q5RI18_HUMAN,tr|A0A1W2PP35|A0A1W2PP35_HUMAN,tr|A0A1W2PPS1|A0A1W2PPS1_HUMAN,tr|A0A1W2PRZ7|A0A1W2PRZ7_HUMAN,tr|A0A1W2PPH7|A0A1W2PPH7_HUMAN,tr|A0A1W2PP34|A0A1W2PP34_HUMAN,tr|A0A1X7SBS1|A0A1X7SBS1_HUMAN" 11 1609.6766 0.89 102182 15276 2 1609.672767 805.8456 Heterogeneous nuclear ribonucleoprotein U OS=Homo sapiens OX=9606 GN=HNRNPU PE=1 SV=6 6.73 2649.6 - 137780 - - - -2.37 - 3.062 0.771 - 611.7 1 1 0 -0.0038 13 0 0 0 3.60E+06 4.05E+06 - - - 7.6065 0.9999 221125_WJC_METTL3_EV_vs_WT_F07.15277.15277.2 8.49E-05 Aug-34 R.SSDEPMTTFVVC[160.03]NEC[160.03]GNR.W "sp|Q15560|TCEA2_HUMAN,tr|A0A0A0MT58|A0A0A0MT58_HUMAN" 2 2101.8503 0.93 102183 15277 2 2101.849517 1051.9324 Transcription elongation factor A protein 2 OS=Homo sapiens OX=9606 GN=TCEA2 PE=1 SV=1 4.14 2649.7 - 105867 - - - -0.3844 - 1.769 0.622 - 135.3 1 2 0 -0.0008 18 0 0 0 1.75E+06 1.88E+06 - - - 5.0372 0.9883 221125_WJC_METTL3_EV_vs_WT_F07.15285.15285.3 0.273 Nov-56 K.KAEAGAGSATEFQFR.G "sp|Q9NQ39|RS10L_HUMAN,sp|P46783|RS10_HUMAN" 2 1568.7583 1.58 102189 15285 3 1568.763661 523.9267 Putative 40S ribosomal protein S10-like OS=Homo sapiens OX=9606 GN=RPS10P5 PE=5 SV=1 6.14 2650.8 - 267108 - - - 3.4046 - 2.04 0.21 - 147.3 1 2 0 0.0053 15 0 0 0 7.14E+06 4.51E+06 - - - 2.7402 1 221125_WJC_METTL3_EV_vs_WT_F07.15286.15286.2 1.52E-14 15/24 L.C[160.03]HNC[160.03]AVEFNFGQK[136.11].E "sp|Q00839|HNRPU_HUMAN,tr|A0A1W2PQL0|A0A1W2PQL0_HUMAN,tr|A0A1W2PPL4|A0A1W2PPL4_HUMAN,tr|A0A1W2PQ74|A0A1W2PQ74_HUMAN,tr|Q5RI18|Q5RI18_HUMAN,tr|A0A1W2PP35|A0A1W2PP35_HUMAN,tr|A0A1W2PPS1|A0A1W2PPS1_HUMAN,tr|A0A1W2PRZ7|A0A1W2PRZ7_HUMAN,tr|A0A1W2PPH7|A0A1W2PPH7_HUMAN,tr|A0A1W2PP34|A0A1W2PP34_HUMAN,tr|A0A1X7SBS1|A0A1X7SBS1_HUMAN" 11 1617.6908 0.89 102190 15286 2 1617.692059 809.8527 Heterogeneous nuclear ribonucleoprotein U OS=Homo sapiens OX=9606 GN=HNRNPU PE=1 SV=6 6.73 2650.9 - 258763 - - - 0.7894 - 3.434 0.769 - 710.9 1 1 0 0.0013 13 0 0 0 3.60E+06 4.05E+06 - - - 7.8868 1 221125_WJC_METTL3_EV_vs_WT_F07.15287.15287.2 9.46E-10 30-Dec K.EILGTAQSVGC[160.03]NVDGR.H sp|P30050|RL12_HUMAN 1 1674.7995 2.5 102191 15287 2 1674.800139 838.407 60S ribosomal protein L12 OS=Homo sapiens OX=9606 GN=RPL12 PE=1 SV=1 4.37 2651.1 - 167999 - - - 0.3618 - 2.597 0.648 - 492.5 1 2 0 0.0006 16 0 0 0 1.91E+06 7.65E+05 - - - 6.1733 0.875 221125_WJC_METTL3_EV_vs_WT_F07.15288.15288.2 0.0864 Jun-32 K.ASESSKPWPDATYGTGS.A "sp|Q9Y2W1|TR150_HUMAN,tr|A0A3B3ITZ9|A0A3B3ITZ9_HUMAN" 2 1739.7639 11.34 102192 15288 2 1739.765385 870.8892 Thyroid hormone receptor-associated protein 3 OS=Homo sapiens OX=9606 GN=THRAP3 PE=1 SV=2 4.37 2651.2 - 165346 - - - 0.8771 - 1.288 0.294 - 40.2 1 1 0 0.0015 17 0 0 0 2.70E+06 2.38E+05 - - - 1.8342 0.9995 221125_WJC_METTL3_EV_vs_WT_F07.15289.15289.2 0.00222 30-Jun R.ELNNSTNGIVIEPSEK.A "sp|Q14681|KCTD2_HUMAN,tr|J3QSC8|J3QSC8_HUMAN" 2 1742.8687 999 102193 15289 2 1742.87028 872.4416 BTB\POZ domain-containing protein KCTD2 OS=Homo sapiens OX=9606 GN=KCTD2 PE=1 SV=3 4.25 2651.3 - 119722 - - - 0.9301 - 1.594 0.417 - 54.9 1 2 0 0.0016 16 0 0 0 1.86E+06 0.00E+00 - - - 3.2667 0.9992 221125_WJC_METTL3_EV_vs_WT_F07.15292.15292.2 0.000159 18-Nov K.YEELQITAGR.H "sp|P04264|K2C1_HUMAN,sp|P04259|K2C6B_HUMAN" 2 1178.5932 26.73 102194 15292 2 1178.595622 590.3039 "Keratin, type II cytoskeletal 1 OS=Homo sapiens OX=9606 GN=KRT1 PE=1 SV=6" 4.53 2651.8 - 1.32E+06 - - - 2.0957 - 2.274 0.293 - 493 1 2 0 0.0025 10 0 0 0 1.82E+07 6.80E+05 - - - 3.4975 1 221125_WJC_METTL3_EV_vs_WT_F07.15293.15293.3 2.61E-10 17/60 R.MTQNPNYYNLQGISHR.H sp|O75643|U520_HUMAN 1 1934.9057 1.08 102195 15293 3 1934.908813 645.9759 U5 small nuclear ribonucleoprotein 200 kDa helicase OS=Homo sapiens OX=9606 GN=SNRNP200 PE=1 SV=2 8.36 2651.9 - 1.13E+06 - - - 1.5939 - 3.12 0.625 - 410.4 1 2 0 0.0031 16 0 0 0 3.51E+07 3.24E+07 - - - 8.4268 0.9848 221125_WJC_METTL3_EV_vs_WT_F07.15297.15297.3 3.22E-05 Dec-68 K.YVHYEIDAC[160.03]MDSEAPGSK[136.11].D "sp|Q86U44|MTA70_HUMAN,tr|H0YFV6|H0YFV6_HUMAN" 2 2078.8805 0.01 102199 15297 3 2079.873605 693.9674 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 4.31 2652.4 - 375485 - - - 477.7153 - 2.473 0.52 - 153 1 2 0 0.9931 18 0 0 0 1.29E+06 9.65E+07 - - - 6.317 1 221125_WJC_METTL3_EV_vs_WT_F07.15298.15298.3 0.000692 24/68 R.ALQDLENAASGDAAVHQR.L "sp|Q96P16|RPR1A_HUMAN,tr|A0A0C4DGQ6|A0A0C4DGQ6_HUMAN,tr|K7EP82|K7EP82_HUMAN" 3 1864.9028 1.79 102200 15298 3 1864.906448 622.6415 Regulation of nuclear pre-mRNA domain-containing protein 1A OS=Homo sapiens OX=9606 GN=RPRD1A PE=1 SV=1 4.54 2652.5 - 349511 - - - 1.9813 - 3.934 0.528 - 894.2 1 2 0 0.0037 18 0 0 0 7.63E+07 4.26E+07 - - - 7.8362 0.8535 221125_WJC_METTL3_EV_vs_WT_F07.15299.15299.2 5.81 12-Jun R.SIFDHIK[136.11].L "sp|Q9NYF8|BCLF1_HUMAN,tr|E9PKI6|E9PKI6_HUMAN,tr|A0A1W2PQ43|A0A1W2PQ43_HUMAN,tr|E9PK91|E9PK91_HUMAN,tr|E9PJA7|E9PJA7_HUMAN,tr|E9PK09|E9PK09_HUMAN,tr|E9PQN2|E9PQN2_HUMAN" 7 866.4742 1.32 102201 15299 2 866.474223 434.2444 Bcl-2-associated transcription factor 1 OS=Homo sapiens OX=9606 GN=BCLAF1 PE=1 SV=2 6.46 2652.6 - 262690 - - - 0.0808 - 0.771 0.084 - 92.2 1 2 0 0.0001 7 0 0 0 4.71E+06 3.57E+06 - - - -1.1626 0.8186 221125_WJC_METTL3_EV_vs_WT_F07.15300.15300.2 0.00197 Jul-34 R.SSDEPMTTFVVC[160.03]NEC[160.03]GNR[166.11].W "sp|Q15560|TCEA2_HUMAN,tr|A0A0A0MT58|A0A0A0MT58_HUMAN" 2 2111.8586 0.93 102202 15300 2 2112.873316 1056.9366 Transcription elongation factor A protein 2 OS=Homo sapiens OX=9606 GN=TCEA2 PE=1 SV=1 4.14 2652.8 - 224950 - - - 480.4872 - 1.556 0.571 - 70.5 1 2 0 1.0147 18 0 0 0 1.75E+06 1.88E+06 - - - 4.0268 0.9995 221125_WJC_METTL3_EV_vs_WT_F07.15301.15301.3 0.000587 Nov-40 R.LLASTLVHSVK.K "sp|Q9NYF8|BCLF1_HUMAN,tr|E9PKI6|E9PKI6_HUMAN,tr|A0A1W2PQ43|A0A1W2PQ43_HUMAN,tr|E9PK91|E9PK91_HUMAN,tr|E9PJA7|E9PJA7_HUMAN,tr|E9PK09|E9PK09_HUMAN,tr|E9PQN2|E9PQN2_HUMAN" 7 1166.7023 2.09 102203 15301 3 1166.703688 389.908 Bcl-2-associated transcription factor 1 OS=Homo sapiens OX=9606 GN=BCLAF1 PE=1 SV=2 8.76 2652.9 - 195059 - - - 1.182 - 2.231 0.279 - 92 1 2 0 0.0014 11 0 0 0 1.36E+07 6.50E+06 - - - 3.9298 0.9999 221125_WJC_METTL3_EV_vs_WT_F07.15304.15304.3 5.76E-05 13/72 K.ITKPGSIDSNNQLFAPGGR.L "sp|Q04637|IF4G1_HUMAN,tr|E7EUU4|E7EUU4_HUMAN,tr|E9PGM1|E9PGM1_HUMAN,tr|E7EX73|E7EX73_HUMAN,tr|A0A7I2Y1C3|A0A7I2Y1C3_HUMAN" 5 1971.0174 0.78 102205 15304 3 1971.023144 658.0131 Eukaryotic translation initiation factor 4 gamma 1 OS=Homo sapiens OX=9606 GN=EIF4G1 PE=1 SV=4 8.75 2653.2 - 991570 - - - 2.9203 - 2.715 0.505 - 102.1 1 2 0 0.0058 19 0 0 0 1.81E+07 2.33E+07 - - - 6.6225 0.9998 221125_WJC_METTL3_EV_vs_WT_F07.15305.15305.3 1.33E-08 21/56 K.HLAGLGLTEAIDKNK.A "sp|P50454|SERPH_HUMAN,tr|E9PKH2|E9PKH2_HUMAN,tr|E9PJH8|E9PJH8_HUMAN" 3 1578.873 1.43 102206 15305 3 1578.8768 527.2983 Serpin H1 OS=Homo sapiens OX=9606 GN=SERPINH1 PE=1 SV=2 6.75 2653.3 - 3.16E+06 - - - 2.4346 - 3.757 0.477 - 737.7 1 2 1 0.0038 15 0 0 0 3.07E+07 2.15E+07 - - - 7.3108 0.9444 221125_WJC_METTL3_EV_vs_WT_F07.15308.15308.2 0.00507 22-Jul K.DHTPSQELALTQ.S "sp|Q86U44|MTA70_HUMAN,tr|H0YFV6|H0YFV6_HUMAN" 2 1338.6416 - 102209 15308 2 1338.638877 670.3281 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 4.35 2653.6 - 249890 - - - -2.0035 - 1.444 0.422 - 157.9 1 1 0 -0.0027 12 0 0 0 - - - - - 3.1238 0.9999 221125_WJC_METTL3_EV_vs_WT_F07.15309.15309.4 6.95E-06 15/72 K.ELHINLIPNK[136.11]QDR[166.11].T "sp|P07900|HS90A_HUMAN,tr|G3V2J8|G3V2J8_HUMAN" 2 1606.891 0.72 102210 15309 4 1606.891317 402.73 Heat shock protein HSP 90-alpha OS=Homo sapiens OX=9606 GN=HSP90AA1 PE=1 SV=5 6.85 2653.7 - 220895 - - - 0.1917 - 2.258 0.522 - 252.4 1 2 1 0.0003 13 0 0 0 7.72E+07 1.08E+08 - - - 4.0714 1 221125_WJC_METTL3_EV_vs_WT_F07.15310.15310.3 1.96E-05 Nov-92 R.APSTSPSFEGTQETYTVAHEENVR.F sp|Q9BUT9|MCRI2_HUMAN 1 2636.1991 26.6 102211 15310 3 2636.200163 879.7403 MAPK regulated corepressor interacting protein 2 OS=Homo sapiens OX=9606 GN=MCRIP2 PE=1 SV=2 4.48 2653.9 - 174251 - - - 0.4207 - 2.536 0.507 - 79.2 1 2 0 0.0011 24 0 0 0 1.86E+06 6.98E+04 - - - 6.3536 1 221125_WJC_METTL3_EV_vs_WT_F07.15315.15315.4 7.14E-07 16/84 R.AHQLVMEGYNWC[160.03]HDR[166.11].N "sp|P67775|PP2AA_HUMAN,sp|P62714|PP2AB_HUMAN,tr|H0YC23|H0YC23_HUMAN" 3 1924.8336 1.46 102214 15315 4 1924.834408 482.2157 Serine\threonine-protein phosphatase 2A catalytic subunit alpha isoform OS=Homo sapiens OX=9606 GN=PPP2CA PE=1 SV=1 5.99 2654.5 - 807080 - - - 0.3985 - 2.995 0.597 - 280.1 1 2 0 0.0008 15 0 0 0 1.15E+07 7.91E+06 - - - 4.8146 1 221125_WJC_METTL3_EV_vs_WT_F07.15316.15316.3 3.09E-05 Dec-68 K.GINSSNVENQLQATQAAR.K "sp|P52292|IMA1_HUMAN,tr|J3QLL0|J3QLL0_HUMAN,tr|J3KS65|J3KS65_HUMAN,tr|A0A7I2V3Z3|A0A7I2V3Z3_HUMAN,tr|A0A7I2YQE1|A0A7I2YQE1_HUMAN,tr|A0A7I2V487|A0A7I2V487_HUMAN,tr|A0A7I2V351|A0A7I2V351_HUMAN" 7 1899.9399 1.22 102215 15316 3 1899.940422 634.3206 Importin subunit alpha-1 OS=Homo sapiens OX=9606 GN=KPNA2 PE=1 SV=1 6 2654.6 - 826565 - - - 0.2926 - 2.61 0.468 - 159.7 1 2 0 0.0006 18 0 0 0 6.80E+07 5.59E+07 - - - 6.1465 0.9999 221125_WJC_METTL3_EV_vs_WT_F07.15320.15320.4 3.57E-06 13/84 K.DKFNEC[160.03]GHVLYADIK.M "sp|P52272|HNRPM_HUMAN,tr|A0A087X0X3|A0A087X0X3_HUMAN" 2 1807.8563 1.72 102219 15320 4 1807.856683 452.9714 Heterogeneous nuclear ribonucleoprotein M OS=Homo sapiens OX=9606 GN=HNRNPM PE=1 SV=3 5.38 2655.1 - 226149 - - - 0.2008 - 2.401 0.546 - 102 1 2 1 0.0004 15 0 0 0 2.99E+08 1.74E+08 - - - 4.2917 1 221125_WJC_METTL3_EV_vs_WT_F07.15321.15321.2 5.25E-12 16/34 K.GINSSNVENQLQATQAAR.K "sp|P52292|IMA1_HUMAN,tr|J3QLL0|J3QLL0_HUMAN,tr|J3KS65|J3KS65_HUMAN,tr|A0A7I2V3Z3|A0A7I2V3Z3_HUMAN,tr|A0A7I2YQE1|A0A7I2YQE1_HUMAN,tr|A0A7I2V487|A0A7I2V487_HUMAN,tr|A0A7I2V351|A0A7I2V351_HUMAN" 7 1899.9399 1.32 102220 15321 2 1899.93732 950.9772 Importin subunit alpha-1 OS=Homo sapiens OX=9606 GN=KPNA2 PE=1 SV=1 6 2655.2 - 205832 - - - -1.34 - 3.643 0.668 - 690.3 1 2 0 -0.0025 18 0 0 0 2.71E+07 2.05E+07 - - - 7.1525 0.9723 221125_WJC_METTL3_EV_vs_WT_F07.15322.15322.3 0.814 Jul-64 R.EDVTFEDHPLNPNPDSR.W sp|Q9NVG8|TBC13_HUMAN 1 1980.8813 0.97 102221 15322 3 1980.878036 661.3011 TBC1 domain family member 13 OS=Homo sapiens OX=9606 GN=TBC1D13 PE=1 SV=3 4.1 2655.4 - 190416 - - - -1.672 - 1.279 0.202 - 37.2 1 2 0 -0.0033 17 0 0 0 3.18E+06 3.27E+06 - - - 1.4129 1 221125_WJC_METTL3_EV_vs_WT_F07.15326.15326.4 7.51E-05 17/84 K.THINIVVIGHVDSGK[136.11].S "sp|Q05639|EF1A2_HUMAN,sp|P68104|EF1A1_HUMAN,sp|Q5VTE0|EF1A3_HUMAN,tr|A0A2R8Y488|A0A2R8Y488_HUMAN,tr|A0A2R8YDN5|A0A2R8YDN5_HUMAN,tr|A0A7I2V659|A0A7I2V659_HUMAN,tr|A0A7I2V3H3|A0A7I2V3H3_HUMAN,tr|Q5JR01|Q5JR01_HUMAN,tr|A0A2U3TZH3|A0A2U3TZH3_HUMAN,tr|A0A7I2V5N4|A0A7I2V5N4_HUMAN,tr|A0A087WVQ9|A0A087WVQ9_HUMAN,tr|A6PW80|A6PW80_HUMAN,tr|A0A087WV01|A0A087WV01_HUMAN,tr|A0A2R8Y660|A0A2R8Y660_HUMAN,tr|A0A6Q8PFK6|A0A6Q8PFK6_HUMAN" 15 1595.8875 0.37 102224 15326 4 1595.889797 399.9791 Elongation factor 1-alpha 2 OS=Homo sapiens OX=9606 GN=EEF1A2 PE=1 SV=1 6.61 2656 - 829142 - - - 1.4456 - 3.307 0.578 - 413 1 2 0 0.0023 15 0 0 0 2.57E+06 7.00E+06 - - - 4.6842 0.9931 221125_WJC_METTL3_EV_vs_WT_F07.15328.15328.3 3.80E-06 18/56 K.NVQDAIADAEQRGEH.A sp|P35908|K22E_HUMAN 1 1651.755 46.3 102225 15328 3 1651.756623 551.5923 "Keratin, type II cytoskeletal 2 epidermal OS=Homo sapiens OX=9606 GN=KRT2 PE=1 SV=2" 4.31 2656.2 - 1.55E+06 - - - 0.9669 - 3.256 0.549 - 249.5 1 1 1 0.0016 15 0 0 0 2.46E+07 5.31E+05 - - - 7.7407 0.9999 221125_WJC_METTL3_EV_vs_WT_F07.15331.15331.3 3.14E-06 15/56 K.DKFNEC[160.03]GHVLYADIK.M "sp|P52272|HNRPM_HUMAN,tr|A0A087X0X3|A0A087X0X3_HUMAN" 2 1807.8563 1.67 102228 15331 3 1807.857375 603.626 Heterogeneous nuclear ribonucleoprotein M OS=Homo sapiens OX=9606 GN=HNRNPM PE=1 SV=3 5.38 2656.5 - 793249 - - - 0.5836 - 2.969 0.566 - 197.7 1 2 1 0.0011 15 0 0 0 3.31E+08 1.98E+08 - - - 7.6896 1 221125_WJC_METTL3_EV_vs_WT_F07.15332.15332.2 6.32E-09 17/34 K.GINSSNVENQLQATQAAR[166.11].K "sp|P52292|IMA1_HUMAN,tr|J3QLL0|J3QLL0_HUMAN,tr|J3KS65|J3KS65_HUMAN,tr|A0A7I2V3Z3|A0A7I2V3Z3_HUMAN,tr|A0A7I2YQE1|A0A7I2YQE1_HUMAN,tr|A0A7I2V487|A0A7I2V487_HUMAN,tr|A0A7I2V351|A0A7I2V351_HUMAN" 7 1909.9481 1.32 102229 15332 2 1909.949112 955.9813 Importin subunit alpha-1 OS=Homo sapiens OX=9606 GN=KPNA2 PE=1 SV=1 6 2656.6 - 536115 - - - 0.511 - 3.863 0.637 - 933.1 1 2 0 0.001 18 0 0 0 2.71E+07 2.05E+07 - - - 7.0682 1 221125_WJC_METTL3_EV_vs_WT_F07.15339.15339.3 3.04E-06 21/48 K.RTGQPMIHIYLDK.E "sp|Q01844|EWS_HUMAN,tr|B0QYK0|B0QYK0_HUMAN,tr|H7BY36|H7BY36_HUMAN,tr|A0A0D9SFL3|A0A0D9SFL3_HUMAN,tr|C9JGE3|C9JGE3_HUMAN" 5 1570.829 0.94 102236 15339 3 1570.831529 524.6169 RNA-binding protein EWS OS=Homo sapiens OX=9606 GN=EWSR1 PE=1 SV=1 8.6 2657.4 - 365071 - - - 1.6208 - 3.788 0.51 - 742.6 1 2 0 0.0025 13 0 0 0 9.95E+06 1.06E+07 - - - 7.8363 0.9999 221125_WJC_METTL3_EV_vs_WT_F07.15343.15343.4 1.33E-07 14/84 K.DK[136.11]FNEC[160.03]GHVLYADIK[136.11].M "sp|P52272|HNRPM_HUMAN,tr|A0A087X0X3|A0A087X0X3_HUMAN" 2 1823.8847 1.72 102238 15343 4 1823.886148 456.9785 Heterogeneous nuclear ribonucleoprotein M OS=Homo sapiens OX=9606 GN=HNRNPM PE=1 SV=3 5.38 2658 - 2.58E+06 - - - 0.7829 - 2.951 0.546 - 144.4 1 2 1 0.0014 15 0 0 0 2.99E+08 1.74E+08 - - - 4.3652 1 221125_WJC_METTL3_EV_vs_WT_F07.15344.15344.3 1.19E-10 19/56 K.DK[136.11]FNEC[160.03]GHVLYADIK[136.11].M "sp|P52272|HNRPM_HUMAN,tr|A0A087X0X3|A0A087X0X3_HUMAN" 2 1823.8847 1.67 102239 15344 3 1823.885096 608.9688 Heterogeneous nuclear ribonucleoprotein M OS=Homo sapiens OX=9606 GN=HNRNPM PE=1 SV=3 5.38 2658 - 2.19E+06 - - - 0.2062 - 3.471 0.642 - 342 1 2 1 0.0004 15 0 0 0 3.32E+08 1.98E+08 - - - 8.9448 1 221125_WJC_METTL3_EV_vs_WT_F07.15345.15345.3 4.80E-12 24/68 R.ALQDLENAASGDAAVHQR[166.11].L "sp|Q96P16|RPR1A_HUMAN,tr|A0A0C4DGQ6|A0A0C4DGQ6_HUMAN,tr|K7EP82|K7EP82_HUMAN" 3 1874.911 1.79 102240 15345 3 1874.912267 625.9776 Regulation of nuclear pre-mRNA domain-containing protein 1A OS=Homo sapiens OX=9606 GN=RPRD1A PE=1 SV=1 4.54 2658.1 - 4.42E+06 - - - 0.6635 - 3.771 0.657 - 822.8 1 2 0 0.0012 18 0 0 0 7.63E+07 4.26E+07 - - - 9.1698 0.9996 221125_WJC_METTL3_EV_vs_WT_F07.15348.15348.3 0.000184 Dec-72 K.ITK[136.11]PGSIDSNNQLFAPGGR[166.11].L "sp|Q04637|IF4G1_HUMAN,tr|E7EUU4|E7EUU4_HUMAN,tr|E9PGM1|E9PGM1_HUMAN,tr|E7EX73|E7EX73_HUMAN,tr|A0A7I2Y1C3|A0A7I2Y1C3_HUMAN" 5 1989.0399 0.97 102243 15348 3 1989.044677 664.0206 Eukaryotic translation initiation factor 4 gamma 1 OS=Homo sapiens OX=9606 GN=EIF4G1 PE=1 SV=4 8.75 2658.4 - 1.29E+06 - - - 2.4228 - 2.137 0.393 - 118.6 1 2 0 0.0048 19 0 0 0 1.90E+07 1.95E+07 - - - 4.7859 1 221125_WJC_METTL3_EV_vs_WT_F07.15349.15349.4 8.82E-09 18/96 R.SHGVLLEVQYSSSIHDR.E "sp|Q8WV92|MITD1_HUMAN,tr|B8ZZL5|B8ZZL5_HUMAN,tr|H7C3Q6|H7C3Q6_HUMAN" 3 1925.9595 1.09 102244 15349 4 1925.960315 482.4972 MIT domain-containing protein 1 OS=Homo sapiens OX=9606 GN=MITD1 PE=1 SV=1 5.94 2658.4 - 940040 - - - 0.4029 - 3.856 0.585 - 332.9 1 2 0 0.0008 17 0 0 0 7.98E+06 7.30E+06 - - - 4.7862 1 221125_WJC_METTL3_EV_vs_WT_F07.15350.15350.3 1.47E-10 22/64 R.SHGVLLEVQYSSSIHDR.E "sp|Q8WV92|MITD1_HUMAN,tr|B8ZZL5|B8ZZL5_HUMAN,tr|H7C3Q6|H7C3Q6_HUMAN" 3 1925.9595 11.63 102245 15350 3 1925.959774 642.9938 MIT domain-containing protein 1 OS=Homo sapiens OX=9606 GN=MITD1 PE=1 SV=1 5.94 2658.5 - 786927 - - - 0.122 - 4.172 0.677 - 923.3 1 2 0 0.0002 17 0 0 0 7.00E+06 6.02E+05 - - - 9.6964 0.9981 221125_WJC_METTL3_EV_vs_WT_F07.15352.15352.4 0.00306 20/90 K.ELVEFAQDDDRLREER.K sp|Q14677|EPN4_HUMAN 1 2018.9657 1.89 102247 15352 4 2018.9712 505.7487 Clathrin interactor 1 OS=Homo sapiens OX=9606 GN=CLINT1 PE=1 SV=1 4.2 2658.8 - 685554 - - - 2.7009 - 2.765 0.374 - 359.9 1 2 2 0.0055 16 0 0 0 1.19E+07 6.30E+06 - - - 2.838 0.992 221125_WJC_METTL3_EV_vs_WT_F07.15353.15353.4 0.0967 17/90 K.ELVEFAQDDDR[166.11]LR[166.11]EER[166.11].K sp|Q14677|EPN4_HUMAN 1 2048.9906 1.89 102248 15353 4 2048.990372 513.2549 Clathrin interactor 1 OS=Homo sapiens OX=9606 GN=CLINT1 PE=1 SV=1 4.2 2658.9 - 600780 - - - -0.0903 - 2.784 0.25 - 320.9 1 2 2 -0.0002 16 0 0 0 1.19E+07 6.30E+06 - - - 1.7626 1 221125_WJC_METTL3_EV_vs_WT_F07.15356.15356.3 1.95E-07 16/60 R.KENGPVVETVQVPLSK.R sp|Q8TCS8|PNPT1_HUMAN 1 1722.9516 1.27 102251 15356 3 1722.951599 575.3245 "Polyribonucleotide nucleotidyltransferase 1, mitochondrial OS=Homo sapiens OX=9606 GN=PNPT1 PE=1 SV=2" 6.14 2659.3 - 394345 - - - -0.0006 - 3.191 0.526 - 305.3 1 2 0 0 16 0 0 0 8.82E+06 6.96E+06 - - - 7.3816 0.9763 221125_WJC_METTL3_EV_vs_WT_F07.15358.15358.3 1.74 Oct-52 K.DNGIR[166.11]PSSLEQMAK[136.11].L "sp|P55084|ECHB_HUMAN,tr|F5GZQ3|F5GZQ3_HUMAN,tr|B5MD38|B5MD38_HUMAN" 3 1562.7842 0.26 102253 15358 3 1562.789693 521.9353 "Trifunctional enzyme subunit beta, mitochondrial OS=Homo sapiens OX=9606 GN=HADHB PE=1 SV=3" 6.07 2659.5 - 230915 - - - 3.5398 - 2.083 0.166 - 106.9 1 2 0 0.0055 14 0 0 0 2.09E+06 8.07E+06 - - - 2.3393 0.9953 221125_WJC_METTL3_EV_vs_WT_F07.15360.15360.3 0.0045 17/48 K.R[166.11]TGQPMIHIYLDK[136.11].E "sp|Q01844|EWS_HUMAN,tr|B0QYK0|B0QYK0_HUMAN,tr|H7BY36|H7BY36_HUMAN,tr|A0A0D9SFL3|A0A0D9SFL3_HUMAN,tr|C9JGE3|C9JGE3_HUMAN" 5 1588.8515 0.82 102254 15360 3 1588.862818 530.6244 RNA-binding protein EWS OS=Homo sapiens OX=9606 GN=EWSR1 PE=1 SV=1 8.6 2659.7 - 1.84E+06 - - - 7.153 - 3.282 0.334 - 416.4 1 2 0 0.0114 13 0 0 0 6.64E+06 8.08E+06 - - - 5.4829 0.9997 221125_WJC_METTL3_EV_vs_WT_F07.15362.15362.4 2.42E-05 15/90 R.LHTLEEEK[136.11]EELAQYQK[136.11].W sp|Q9UQE7|SMC3_HUMAN 1 2003.0182 0.76 102255 15362 4 2003.019258 501.7618 Structural maintenance of chromosomes protein 3 OS=Homo sapiens OX=9606 GN=SMC3 PE=1 SV=2 4.64 2660 - 2.49E+06 - - - 0.5102 - 2.723 0.438 - 180.6 1 2 1 0.001 16 0 0 0 2.82E+07 3.71E+07 - - - 3.3909 1 221125_WJC_METTL3_EV_vs_WT_F07.15363.15363.3 8.00E-06 20/60 R.LHTLEEEK[136.11]EELAQYQK[136.11].W sp|Q9UQE7|SMC3_HUMAN 1 2003.0182 0.58 102256 15363 3 2003.018881 668.68 Structural maintenance of chromosomes protein 3 OS=Homo sapiens OX=9606 GN=SMC3 PE=1 SV=2 4.64 2660 - 2.39E+06 - - - 0.322 - 3.785 0.566 - 394.1 1 2 1 0.0006 16 0 0 0 2.40E+07 4.16E+07 - - - 8.2654 1 221125_WJC_METTL3_EV_vs_WT_F07.15364.15364.3 6.73E-09 19/68 K.GINSSNVENQLQATQAAR[166.11].K "sp|P52292|IMA1_HUMAN,tr|J3QLL0|J3QLL0_HUMAN,tr|J3KS65|J3KS65_HUMAN,tr|A0A7I2V3Z3|A0A7I2V3Z3_HUMAN,tr|A0A7I2YQE1|A0A7I2YQE1_HUMAN,tr|A0A7I2V487|A0A7I2V487_HUMAN,tr|A0A7I2V351|A0A7I2V351_HUMAN" 7 1909.9481 1.22 102257 15364 3 1909.947743 637.6567 Importin subunit alpha-1 OS=Homo sapiens OX=9606 GN=KPNA2 PE=1 SV=1 6 2660.1 - 6.08E+06 - - - -0.2058 - 3.379 0.596 - 366.8 1 2 0 -0.0004 18 0 0 0 6.81E+07 5.59E+07 - - - 8.2166 0.9991 221125_WJC_METTL3_EV_vs_WT_F07.15365.15365.4 0.000301 Dec-90 R.LHTLEEEKEELAQYQK.W sp|Q9UQE7|SMC3_HUMAN 1 1986.9898 0.76 102258 15365 4 1986.992069 497.7547 Structural maintenance of chromosomes protein 3 OS=Homo sapiens OX=9606 GN=SMC3 PE=1 SV=2 4.64 2660.1 - 1.86E+06 - - - 1.1238 - 2.527 0.367 - 91.7 1 2 1 0.0022 16 0 0 0 2.82E+07 3.70E+07 - - - 2.7463 1 221125_WJC_METTL3_EV_vs_WT_F07.15368.15368.4 2.32E-08 17/108 K.LC[160.03]LTLHNNEGSYLAHTQGK[136.11].K "sp|Q15428|SF3A2_HUMAN,tr|K7EMT0|K7EMT0_HUMAN" 2 2163.0622 1.03 102261 15368 4 2163.064037 541.7728 Splicing factor 3A subunit 2 OS=Homo sapiens OX=9606 GN=SF3A2 PE=1 SV=2 6.91 2660.4 - 1.19E+06 - - - 0.8322 - 3.25 0.528 - 204.7 1 2 0 0.0018 19 0 0 0 6.93E+06 6.73E+06 - - - 4.2199 0.9999 221125_WJC_METTL3_EV_vs_WT_F07.15369.15369.4 5.33E-07 19/102 K.LLNTVEETTKDVSGLHSK.L "sp|P52732|KIF11_HUMAN,tr|A0A7I2YQY4|A0A7I2YQY4_HUMAN,tr|A0A7I2V3A9|A0A7I2V3A9_HUMAN" 3 1970.032 4.57 102262 15369 4 1970.033779 493.5153 Kinesin-like protein KIF11 OS=Homo sapiens OX=9606 GN=KIF11 PE=1 SV=2 5.45 2660.4 - 1.09E+06 - - - 0.8848 - 3.304 0.497 - 245.2 1 2 1 0.0017 18 0 0 0 5.91E+08 1.29E+08 - - - 3.9608 1 221125_WJC_METTL3_EV_vs_WT_F07.15370.15370.3 9.39E-07 22/56 R.RNLGSINTELQDVQR.L "sp|O75396|SC22B_HUMAN,tr|A0A087X1A9|A0A087X1A9_HUMAN" 2 1741.9071 1.56 102263 15370 3 1741.911122 581.643 Vesicle-trafficking protein SEC22b OS=Homo sapiens OX=9606 GN=SEC22B PE=1 SV=5 6.07 2660.5 - 1.04E+06 - - - 2.3032 - 4.085 0.521 - 1057.7 1 2 0 0.004 15 0 0 0 1.11E+07 7.13E+06 - - - 8.0197 0.9991 221125_WJC_METTL3_EV_vs_WT_F07.15373.15373.3 0.000684 19/80 K.VVSTPPSVTEPPEK[136.11]ELSTVSK[136.11].L "sp|Q92667|AKAP1_HUMAN,tr|I3L364|I3L364_HUMAN,tr|I3L2A2|I3L2A2_HUMAN,tr|I3L0K6|I3L0K6_HUMAN,tr|I3L2N7|I3L2N7_HUMAN" 5 2226.1966 1 102266 15373 3 2226.199829 743.0728 "A-kinase anchor protein 1, mitochondrial OS=Homo sapiens OX=9606 GN=AKAP1 PE=1 SV=1" 4.79 2660.9 - 832676 - - - 1.4527 - 3.018 0.329 - 319.3 1 2 1 0.0032 21 0 0 0 1.22E+07 1.22E+07 - - - 4.8553 1 221125_WJC_METTL3_EV_vs_WT_F07.15375.15375.3 4.81E-08 16/52 K.LTFDSSFSPNTGKK.N "sp|P21796|VDAC1_HUMAN,tr|C9JI87|C9JI87_HUMAN" 2 1527.7569 1.26 102268 15375 3 1527.759547 510.2596 Voltage-dependent anion-selective channel protein 1 OS=Homo sapiens OX=9606 GN=VDAC1 PE=1 SV=2 8.59 2661.1 - 730032 - - - 1.7176 - 3.035 0.532 - 289.1 1 2 0 0.0026 14 0 0 0 2.00E+07 1.58E+07 - - - 7.421 0.9999 221125_WJC_METTL3_EV_vs_WT_F07.15377.15377.2 2.87E-07 30-Oct K.SQASKPAYGNSPYWTN.- sp|Q5T6F2|UBAP2_HUMAN 1 1769.8009 1.85 102270 15377 2 1769.801561 885.9077 Ubiquitin-associated protein 2 OS=Homo sapiens OX=9606 GN=UBAP2 PE=1 SV=1 8.22 2661.4 - 325692 - - - 0.3661 - 2.139 0.605 - 224.8 1 2 0 0.0006 16 0 0 0 2.72E+06 1.47E+06 - - - 5.3787 0.9998 221125_WJC_METTL3_EV_vs_WT_F07.15379.15379.2 8.76E-06 30-Aug K.SQASK[136.11]PAYGNSPYWTN.- sp|Q5T6F2|UBAP2_HUMAN 1 1777.8151 1.85 102272 15379 2 1777.813486 889.9148 Ubiquitin-associated protein 2 OS=Homo sapiens OX=9606 GN=UBAP2 PE=1 SV=1 8.22 2661.6 - 217036 - - - -0.9152 - 1.885 0.507 - 159.3 1 2 0 -0.0016 16 0 0 0 2.72E+06 1.47E+06 - - - 4.3437 1 221125_WJC_METTL3_EV_vs_WT_F07.15382.15382.3 4.30E-09 17/60 R.LHTLEEEKEELAQYQK.W sp|Q9UQE7|SMC3_HUMAN 1 1986.9898 0.58 102273 15382 3 1986.987918 663.3372 Structural maintenance of chromosomes protein 3 OS=Homo sapiens OX=9606 GN=SMC3 PE=1 SV=2 4.64 2662 - 3.04E+06 - - - -0.9653 - 3.442 0.59 - 334.9 1 2 1 -0.0019 16 0 0 0 2.40E+07 4.16E+07 - - - 8.2889 0.9998 221125_WJC_METTL3_EV_vs_WT_F07.15383.15383.3 2.72E-05 18/48 K.ELHINLIPNK[136.11]QDR[166.11].T "sp|P07900|HS90A_HUMAN,tr|G3V2J8|G3V2J8_HUMAN" 2 1606.891 0.81 102274 15383 3 1606.890598 536.6376 Heat shock protein HSP 90-alpha OS=Homo sapiens OX=9606 GN=HSP90AA1 PE=1 SV=5 6.85 2662.1 - 2.63E+06 - - - -0.2558 - 2.803 0.431 - 433.6 1 2 1 -0.0004 13 0 0 0 7.28E+07 8.96E+07 - - - 6.1396 1 221125_WJC_METTL3_EV_vs_WT_F07.15387.15387.3 2.89E-05 18/56 R.R[166.11]NLGSINTELQDVQR[166.11].L "sp|O75396|SC22B_HUMAN,tr|A0A087X1A9|A0A087X1A9_HUMAN" 2 1761.9236 1.56 102278 15387 3 1761.92404 588.3152 Vesicle-trafficking protein SEC22b OS=Homo sapiens OX=9606 GN=SEC22B PE=1 SV=5 6.07 2662.5 - 1.12E+06 - - - 0.2213 - 3.131 0.481 - 667.4 1 2 0 0.0004 15 0 0 0 1.11E+07 7.13E+06 - - - 6.8808 0.9998 221125_WJC_METTL3_EV_vs_WT_F07.15388.15388.3 4.11E-07 19/80 K.VVSTPPSVTEPPEKELSTVSK.L "sp|Q92667|AKAP1_HUMAN,tr|I3L364|I3L364_HUMAN,tr|I3L2A2|I3L2A2_HUMAN,tr|I3L0K6|I3L0K6_HUMAN,tr|I3L2N7|I3L2N7_HUMAN" 5 2210.1682 1.04 102279 15388 3 2210.171229 737.73 "A-kinase anchor protein 1, mitochondrial OS=Homo sapiens OX=9606 GN=AKAP1 PE=1 SV=1" 4.79 2662.6 - 733643 - - - 1.3727 - 2.686 0.525 - 302.8 1 2 1 0.003 21 0 0 0 1.22E+07 1.18E+07 - - - 6.7612 1 221125_WJC_METTL3_EV_vs_WT_F07.15389.15389.2 8.48E-05 16/28 K.DKFNEC[160.03]GHVLYADIK.M "sp|P52272|HNRPM_HUMAN,tr|A0A087X0X3|A0A087X0X3_HUMAN" 2 1807.8563 1.73 102280 15389 2 1807.858175 904.9354 Heterogeneous nuclear ribonucleoprotein M OS=Homo sapiens OX=9606 GN=HNRNPM PE=1 SV=3 5.38 2662.8 - 588804 - - - 1.0261 - 3.716 0.624 - 701 1 2 1 0.0019 15 0 0 0 8.11E+06 4.70E+06 - - - 6.8765 0.9998 221125_WJC_METTL3_EV_vs_WT_F07.15390.15390.4 0.00396 15/72 K.RTGQPMIHIYLDK.E "sp|Q01844|EWS_HUMAN,tr|B0QYK0|B0QYK0_HUMAN,tr|H7BY36|H7BY36_HUMAN,tr|A0A0D9SFL3|A0A0D9SFL3_HUMAN,tr|C9JGE3|C9JGE3_HUMAN" 5 1570.829 0.1 102281 15390 4 1570.82728 393.7145 RNA-binding protein EWS OS=Homo sapiens OX=9606 GN=EWSR1 PE=1 SV=1 8.6 2662.9 - 421145 - - - -1.0841 - 2.443 0.377 - 101.4 1 2 0 -0.0017 13 0 0 0 7.05E+06 6.87E+07 - - - 2.8381 0.9992 221125_WJC_METTL3_EV_vs_WT_F07.15391.15391.2 0.0121 30-Jun K.GGKPEPPAMPQPVPTA.- "sp|P23396|RS3_HUMAN,tr|H0YEU2|H0YEU2_HUMAN,tr|E9PL09|E9PL09_HUMAN,tr|E9PPU1|E9PPU1_HUMAN" 4 1572.797 0.8 102282 15391 2 1572.798747 787.4058 40S ribosomal protein S3 OS=Homo sapiens OX=9606 GN=RPS3 PE=1 SV=2 6 2663 - 220026 - - - 1.1019 - 1.654 0.354 - 63.3 1 2 0 0.0017 16 0 0 0 3.99E+06 4.96E+06 - - - 2.8922 0.9993 221125_WJC_METTL3_EV_vs_WT_F07.15393.15393.4 0.000131 18/84 R.VLSAPPHFHFGQTNR.T sp|P26641|EF1G_HUMAN 1 1706.8641 1.15 102283 15393 4 1706.865426 427.7233 Elongation factor 1-gamma OS=Homo sapiens OX=9606 GN=EEF1G PE=1 SV=3 9.73 2663.2 - 414172 - - - 0.7634 - 3.215 0.298 - 332.2 1 2 0 0.0013 15 0 0 0 6.58E+06 5.73E+06 - - - 2.2373 0.9999 221125_WJC_METTL3_EV_vs_WT_F07.15394.15394.4 0.00314 18/84 R.VLSAPPHFHFGQTNR[166.11].T sp|P26641|EF1G_HUMAN 1 1716.8724 1.1 102284 15394 4 1716.873198 430.2254 Elongation factor 1-gamma OS=Homo sapiens OX=9606 GN=EEF1G PE=1 SV=3 9.73 2663.4 - 549993 - - - 0.4689 - 3.431 0.448 - 377.2 1 2 0 0.0008 15 0 0 0 7.40E+06 6.70E+06 - - - 3.5663 0.9999 221125_WJC_METTL3_EV_vs_WT_F07.15395.15395.4 5.85E-05 15/102 K.LLNTVEETTK[136.11]DVSGLHSK[136.11].L "sp|P52732|KIF11_HUMAN,tr|A0A7I2YQY4|A0A7I2YQY4_HUMAN,tr|A0A7I2V3A9|A0A7I2V3A9_HUMAN" 3 1986.0604 4.57 102285 15395 4 1986.059124 497.5224 Kinesin-like protein KIF11 OS=Homo sapiens OX=9606 GN=KIF11 PE=1 SV=2 5.45 2663.4 - 5.66E+06 - - - -0.6606 - 2.721 0.511 - 146.3 1 2 1 -0.0013 18 0 0 0 5.91E+08 1.29E+08 - - - 4.0163 0.9999 221125_WJC_METTL3_EV_vs_WT_F07.15397.15397.4 6.18E-08 20/120 R.LTSTATKDPEGFVGHPVNAFK.L sp|P13674|P4HA1_HUMAN 1 2215.1273 1.64 102287 15397 4 2215.124495 554.7891 Prolyl 4-hydroxylase subunit alpha-1 OS=Homo sapiens OX=9606 GN=P4HA1 PE=1 SV=2 6.75 2663.5 - 1.93E+06 - - - -1.2812 - 3.492 0.541 - 205.8 1 2 1 -0.0028 21 0 0 0 1.11E+08 6.81E+07 - - - 4.3475 0.9999 221125_WJC_METTL3_EV_vs_WT_F07.15398.15398.4 7.89E-08 21/120 R.LTSTATK[136.11]DPEGFVGHPVNAFK[136.11].L sp|P13674|P4HA1_HUMAN 1 2231.1557 1.64 102288 15398 4 2231.156816 558.7962 Prolyl 4-hydroxylase subunit alpha-1 OS=Homo sapiens OX=9606 GN=P4HA1 PE=1 SV=2 6.75 2663.6 - 1.63E+06 - - - 0.4854 - 3.53 0.508 - 251.6 1 2 1 0.0011 21 0 0 0 1.11E+08 6.81E+07 - - - 4.0644 0.9999 221125_WJC_METTL3_EV_vs_WT_F07.15401.15401.4 1.21E-06 17/120 R.GPAWVGSHGVLQHTQGLPADR.G sp|Q15654|TRIP6_HUMAN 1 2182.1032 0.26 102291 15401 4 2182.101253 546.5331 Thyroid receptor-interacting protein 6 OS=Homo sapiens OX=9606 GN=TRIP6 PE=1 SV=3 6.92 2663.9 - 754610 - - - -0.8849 - 2.891 0.457 - 142.9 1 2 0 -0.0019 21 0 0 0 6.03E+06 2.35E+07 - - - 3.5542 0.9025 221125_WJC_METTL3_EV_vs_WT_F07.15404.15404.2 0.307 12-Aug F.SVTIHMK.E "sp|P52732|KIF11_HUMAN,tr|A0A7I2YQY4|A0A7I2YQY4_HUMAN,tr|A0A7I2V3A9|A0A7I2V3A9_HUMAN,tr|A0A7I2V3V3|A0A7I2V3V3_HUMAN" 4 814.4371 3.98 102294 15404 2 814.436048 408.2258 Kinesin-like protein KIF11 OS=Homo sapiens OX=9606 GN=KIF11 PE=1 SV=2 8.49 2664.3 - 547810 - - - -1.3027 - 1.187 0.347 - 176.7 1 1 0 -0.0011 7 0 0 0 1.58E+07 3.96E+06 - - - 2.1468 1 221125_WJC_METTL3_EV_vs_WT_F07.15405.15405.2 7.28E-06 15/28 K.DK[136.11]FNEC[160.03]GHVLYADIK[136.11].M "sp|P52272|HNRPM_HUMAN,tr|A0A087X0X3|A0A087X0X3_HUMAN" 2 1823.8847 1.73 102295 15405 2 1823.88664 912.9496 Heterogeneous nuclear ribonucleoprotein M OS=Homo sapiens OX=9606 GN=HNRNPM PE=1 SV=3 5.38 2664.4 - 366876 - - - 1.0527 - 3.874 0.622 - 714.1 1 2 1 0.0019 15 0 0 0 8.11E+06 4.70E+06 - - - 6.9641 1 221125_WJC_METTL3_EV_vs_WT_F07.15409.15409.3 6.43E-10 21/68 K.LLNTVEETTK[136.11]DVSGLHSK[136.11].L "sp|P52732|KIF11_HUMAN,tr|A0A7I2YQY4|A0A7I2YQY4_HUMAN,tr|A0A7I2V3A9|A0A7I2V3A9_HUMAN" 3 1986.0604 4.76 102297 15409 3 1986.059221 663.0274 Kinesin-like protein KIF11 OS=Homo sapiens OX=9606 GN=KIF11 PE=1 SV=2 5.45 2665 - 5.50E+06 - - - -0.6118 - 3.658 0.605 - 471.4 1 2 1 -0.0012 18 0 0 0 3.17E+08 6.67E+07 - - - 8.5143 1 221125_WJC_METTL3_EV_vs_WT_F07.15412.15412.3 1.01E-13 26/80 R.LTSTATKDPEGFVGHPVNAFK.L sp|P13674|P4HA1_HUMAN 1 2215.1273 1.53 102300 15412 3 2215.126902 739.3831 Prolyl 4-hydroxylase subunit alpha-1 OS=Homo sapiens OX=9606 GN=P4HA1 PE=1 SV=2 6.75 2665.2 - 1.73E+06 - - - -0.1946 - 4.907 0.641 - 580.9 1 2 1 -0.0004 21 0 0 0 3.36E+07 2.19E+07 - - - 9.4999 1 221125_WJC_METTL3_EV_vs_WT_F07.15413.15413.3 2.67E-06 13/56 K.DQTKPTPLILDEQGR.T sp|O43395|PRPF3_HUMAN 1 1709.8948 2.24 102301 15413 3 1709.895168 570.9722 U4\U6 small nuclear ribonucleoprotein Prp3 OS=Homo sapiens OX=9606 GN=PRPF3 PE=1 SV=2 4.56 2665.2 - 1.26E+06 - - - 0.207 - 2.465 0.467 - 236.4 1 2 0 0.0004 15 0 0 0 1.24E+08 5.56E+07 - - - 6.1006 1 221125_WJC_METTL3_EV_vs_WT_F07.15414.15414.3 1.09E-15 32/80 R.LTSTATK[136.11]DPEGFVGHPVNAFK[136.11].L sp|P13674|P4HA1_HUMAN 1 2231.1557 1.53 102302 15414 3 2231.153328 744.7259 Prolyl 4-hydroxylase subunit alpha-1 OS=Homo sapiens OX=9606 GN=P4HA1 PE=1 SV=2 6.75 2665.4 - 1.23E+06 - - - -1.0779 - 5.345 0.686 - 948.2 1 2 1 -0.0024 21 0 0 0 3.36E+07 2.19E+07 - - - 10.2061 1 221125_WJC_METTL3_EV_vs_WT_F07.15415.15415.3 4.22E-10 24/76 K.AEDPSQPDSAGYTALHYASR.N sp|Q53RE8|ANR39_HUMAN 1 2134.9556 1.66 102303 15415 3 2134.956887 712.6591 Ankyrin repeat domain-containing protein 39 OS=Homo sapiens OX=9606 GN=ANKRD39 PE=1 SV=1 4.54 2665.5 - 1.08E+06 - - - 0.6141 - 4.374 0.65 - 784.4 1 2 0 0.0013 20 0 0 0 1.28E+07 7.69E+06 - - - 9.3665 0.9982 221125_WJC_METTL3_EV_vs_WT_F07.15416.15416.2 0.0112 30-Jul K.GGK[136.11]PEPPAMPQPVPTA.- "sp|P23396|RS3_HUMAN,tr|H0YEU2|H0YEU2_HUMAN,tr|E9PL09|E9PL09_HUMAN,tr|E9PPU1|E9PPU1_HUMAN" 4 1580.8112 0.8 102304 15416 2 1580.809124 791.4129 40S ribosomal protein S3 OS=Homo sapiens OX=9606 GN=RPS3 PE=1 SV=2 6 2665.6 - 266381 - - - -1.3221 - 1.328 0.326 - 77.9 1 2 0 -0.0021 16 0 0 0 3.99E+06 4.96E+06 - - - 2.1456 1 221125_WJC_METTL3_EV_vs_WT_F07.15419.15419.3 1.16E-09 20/68 K.LLNTVEETTKDVSGLHSK.L "sp|P52732|KIF11_HUMAN,tr|A0A7I2YQY4|A0A7I2YQY4_HUMAN,tr|A0A7I2V3A9|A0A7I2V3A9_HUMAN" 3 1970.032 4.76 102305 15419 3 1970.031283 657.6846 Kinesin-like protein KIF11 OS=Homo sapiens OX=9606 GN=KIF11 PE=1 SV=2 5.45 2666 - 3.46E+07 - - - -0.3822 - 4.284 0.692 - 372.6 1 2 1 -0.0008 18 0 0 0 3.17E+08 6.67E+07 - - - 9.8777 1 221125_WJC_METTL3_EV_vs_WT_F07.15422.15422.3 0.000246 15/44 R.SHSVFSVTIHMK[136.11].E "sp|P52732|KIF11_HUMAN,tr|A0A7I2YQY4|A0A7I2YQY4_HUMAN,tr|A0A7I2V3A9|A0A7I2V3A9_HUMAN,tr|A0A7I2V3V3|A0A7I2V3V3_HUMAN" 4 1379.7111 3.61 102308 15422 3 1379.709215 460.911 Kinesin-like protein KIF11 OS=Homo sapiens OX=9606 GN=KIF11 PE=1 SV=2 8.51 2666.2 - 1.57E+06 - - - -1.3706 - 2.834 0.521 - 402.4 1 2 0 -0.0019 12 0 0 0 5.98E+07 1.65E+07 - - - 7.2355 0.9999 221125_WJC_METTL3_EV_vs_WT_F07.15423.15423.3 0.00015 15/56 K.DQTK[136.11]PTPLILDEQGR[166.11].T sp|O43395|PRPF3_HUMAN 1 1727.9173 2.24 102309 15423 3 1727.916172 576.9797 U4\U6 small nuclear ribonucleoprotein Prp3 OS=Homo sapiens OX=9606 GN=PRPF3 PE=1 SV=2 4.56 2666.3 - 1.41E+06 - - - -0.6435 - 2.704 0.422 - 276.4 1 2 0 -0.0011 15 0 0 0 1.24E+08 5.56E+07 - - - 5.8402 0.9999 221125_WJC_METTL3_EV_vs_WT_F07.15424.15424.3 0.00113 Nov-52 K.LTFDSSFSPNTGK[136.11]K[136.11].N "sp|P21796|VDAC1_HUMAN,tr|C9JI87|C9JI87_HUMAN" 2 1543.7853 1.27 102310 15424 3 1543.785805 515.6024 Voltage-dependent anion-selective channel protein 1 OS=Homo sapiens OX=9606 GN=VDAC1 PE=1 SV=2 8.59 2666.4 - 1.15E+06 - - - 0.3122 - 2.241 0.437 - 100.3 1 2 0 0.0005 14 0 0 0 2.01E+07 1.58E+07 - - - 5.5564 1 221125_WJC_METTL3_EV_vs_WT_F07.15434.15434.2 8.16E-12 15/34 K.LLNTVEETTKDVSGLHSK.L "sp|P52732|KIF11_HUMAN,tr|A0A7I2YQY4|A0A7I2YQY4_HUMAN,tr|A0A7I2V3A9|A0A7I2V3A9_HUMAN" 3 1970.032 18.02 102318 15434 2 1970.02984 986.0233 Kinesin-like protein KIF11 OS=Homo sapiens OX=9606 GN=KIF11 PE=1 SV=2 5.45 2667.6 - 396054 - - - -1.1147 - 3.925 0.701 - 505.9 1 2 1 -0.0022 18 0 0 0 4.54E+06 2.52E+05 - - - 7.5796 1 221125_WJC_METTL3_EV_vs_WT_F07.15438.15438.3 2.99E-14 27/76 R.KPYPEDPAVYKPLSQEELQR.L sp|O95628|CNOT4_HUMAN 1 2386.2169 1.99 102320 15438 3 2386.216355 796.4129 CCR4-NOT transcription complex subunit 4 OS=Homo sapiens OX=9606 GN=CNOT4 PE=1 SV=3 4.87 2668.1 - 1.30E+06 - - - -0.2183 - 4.393 0.666 - 652.1 1 2 0 -0.0005 20 0 0 0 1.49E+07 7.51E+06 - - - 9.5556 1 221125_WJC_METTL3_EV_vs_WT_F07.15440.15440.4 0.000124 14/96 R.SLYTHSYEVPDHDNWPK.G sp|Q9BY49|PECR_HUMAN 1 2086.9385 1.4 102321 15440 4 2086.937629 522.7419 Peroxisomal trans-2-enoyl-CoA reductase OS=Homo sapiens OX=9606 GN=PECR PE=1 SV=2 5.2 2668.3 - 1.59E+06 - - - -0.4025 - 2.499 0.473 - 96.7 1 2 0 -0.0008 17 0 0 0 6.06E+07 4.34E+07 - - - 3.6608 1 221125_WJC_METTL3_EV_vs_WT_F07.15441.15441.4 3.72E-07 17/96 R.SLYTHSYEVPDHDNWPK[136.11].G sp|Q9BY49|PECR_HUMAN 1 2094.9527 1.4 102322 15441 4 2094.954 524.7454 Peroxisomal trans-2-enoyl-CoA reductase OS=Homo sapiens OX=9606 GN=PECR PE=1 SV=2 5.2 2668.4 - 880151 - - - 0.6353 - 2.832 0.578 - 128.3 1 2 0 0.0013 17 0 0 0 6.06E+07 4.34E+07 - - - 4.618 1 221125_WJC_METTL3_EV_vs_WT_F07.15442.15442.3 1.71E-07 15/44 R.SHSVFSVTIHMK.E "sp|P52732|KIF11_HUMAN,tr|A0A7I2YQY4|A0A7I2YQY4_HUMAN,tr|A0A7I2V3A9|A0A7I2V3A9_HUMAN,tr|A0A7I2V3V3|A0A7I2V3V3_HUMAN" 4 1371.6969 3.62 102323 15442 3 1371.696897 458.2396 Kinesin-like protein KIF11 OS=Homo sapiens OX=9606 GN=KIF11 PE=1 SV=2 8.51 2668.4 - 5.75E+06 - - - -0.0066 - 2.762 0.576 - 376.7 1 2 0 0 12 0 0 0 5.97E+07 1.65E+07 - - - 7.7779 1 221125_WJC_METTL3_EV_vs_WT_F07.15448.15448.3 5.99E-06 21/76 R.K[136.11]PYPEDPAVYK[136.11]PLSQEELQR[166.11].L sp|O95628|CNOT4_HUMAN 1 2412.2535 1.99 102329 15448 3 2412.245989 805.0918 CCR4-NOT transcription complex subunit 4 OS=Homo sapiens OX=9606 GN=CNOT4 PE=1 SV=3 4.87 2669.2 - 683481 - - - -3.1328 - 4.003 0.592 - 365.4 1 2 0 -0.0076 20 0 0 0 1.49E+07 7.51E+06 - - - 8.5031 1 221125_WJC_METTL3_EV_vs_WT_F07.15452.15452.4 1.93E-09 24/114 R.KPYPEDPAVYKPLSQEELQR.L sp|O95628|CNOT4_HUMAN 1 2386.2169 2.08 102332 15452 4 2386.218938 597.5615 CCR4-NOT transcription complex subunit 4 OS=Homo sapiens OX=9606 GN=CNOT4 PE=1 SV=3 4.87 2669.6 - 5.04E+06 - - - 0.8641 - 4.294 0.642 - 430 1 2 0 0.0021 20 0 0 0 5.80E+07 2.79E+07 - - - 5.3006 0.9616 221125_WJC_METTL3_EV_vs_WT_F07.15453.15453.3 0.000233 15/60 L.NTVEETTKDVSGLHSK.L "sp|P52732|KIF11_HUMAN,tr|A0A7I2YQY4|A0A7I2YQY4_HUMAN,tr|A0A7I2V3A9|A0A7I2V3A9_HUMAN" 3 1743.8639 24.17 102333 15453 3 1743.860648 582.2952 Kinesin-like protein KIF11 OS=Homo sapiens OX=9606 GN=KIF11 PE=1 SV=2 5.45 2669.8 - 633447 - - - -1.8694 - 2.734 0.429 - 224.5 1 1 1 -0.0033 16 0 0 0 1.72E+07 7.12E+05 - - - 5.9027 1 221125_WJC_METTL3_EV_vs_WT_F07.15455.15455.2 6.58E-17 21/38 R.FSSC[160.03]GGGGGSFGAGGGFGSR.S sp|P04264|K2C1_HUMAN 1 1764.7274 999 102335 15455 2 1764.726897 883.371 "Keratin, type II cytoskeletal 1 OS=Homo sapiens OX=9606 GN=KRT1 PE=1 SV=6" 8.25 2670 - 1.22E+06 - - - -0.3026 - 4.135 0.777 - 1351.5 1 2 0 -0.0005 20 0 0 0 5.04E+07 0.00E+00 - - - 8.2696 1 221125_WJC_METTL3_EV_vs_WT_F07.15456.15456.3 2.64E-12 17/76 K.LLNGPGDVETGTSITVPQK[136.11]K[136.11].W "sp|Q9HC07|TM165_HUMAN,tr|V9GY93|V9GY93_HUMAN" 2 2069.1339 1.13 102336 15456 3 2069.133984 690.7186 Transmembrane protein 165 OS=Homo sapiens OX=9606 GN=TMEM165 PE=1 SV=1 6.07 2670.1 - 961793 - - - 0.0237 - 3.191 0.645 - 193.9 1 2 0 0 20 0 0 0 1.13E+07 9.99E+06 - - - 8.5461 1 221125_WJC_METTL3_EV_vs_WT_F07.15457.15457.3 8.44E-07 19/40 K.TK[136.11]PHLFYIPGR[166.11].M sp|Q9H307|PININ_HUMAN 1 1345.7626 2.48 102337 15457 3 1345.761658 449.5948 Pinin OS=Homo sapiens OX=9606 GN=PNN PE=1 SV=5 9.99 2670.2 - 934798 - - - -0.671 - 2.801 0.544 - 553.5 1 2 0 -0.0009 11 0 0 0 2.82E+07 1.14E+07 - - - 7.5308 1 221125_WJC_METTL3_EV_vs_WT_F07.15458.15458.3 9.09E-10 20/72 K.YR[166.11]DVAEC[160.03]GPQQELDLNSPR[166.11].N sp|Q9BTE3|MCMBP_HUMAN 1 2266.0551 1.04 102338 15458 3 2266.053949 756.359 Mini-chromosome maintenance complex-binding protein OS=Homo sapiens OX=9606 GN=MCMBP PE=1 SV=2 4.32 2670.4 - 677638 - - - -0.5234 - 3.981 0.624 - 692.8 1 2 1 -0.0012 19 0 0 0 6.22E+06 5.99E+06 - - - 8.8908 0.9963 221125_WJC_METTL3_EV_vs_WT_F07.15460.15460.3 7.40E-07 15/72 V.HHVVPTEPLPAPGPASVTE.- "sp|Q9BQA1|MEP50_HUMAN,tr|H0Y711|H0Y711_HUMAN" 2 1933.9898 - 102340 15460 3 1933.993021 645.6705 Methylosome protein 50 OS=Homo sapiens OX=9606 GN=WDR77 PE=1 SV=1 5.37 2670.6 - 618691 - - - 1.6774 - 2.766 0.526 - 245.8 1 1 0 0.0032 19 0 0 0 - - - - - 6.903 1 221125_WJC_METTL3_EV_vs_WT_F07.15463.15463.3 4.42E-05 Nov-76 R.FSSC[160.03]GGGGGSFGAGGGFGSR.S sp|P04264|K2C1_HUMAN 1 1764.7274 999 102343 15463 3 1764.727481 589.2498 "Keratin, type II cytoskeletal 1 OS=Homo sapiens OX=9606 GN=KRT1 PE=1 SV=6" 8.25 2671 - 525672 - - - 0.0283 - 2.245 0.571 - 93.7 1 2 0 0.0001 20 0 0 0 1.90E+07 0.00E+00 - - - 6.868 0.9998 221125_WJC_METTL3_EV_vs_WT_F07.15466.15466.2 9.98E-07 28-Nov K.DQTKPTPLILDEQGR.T sp|O43395|PRPF3_HUMAN 1 1709.8948 3.65 102346 15466 2 1709.891269 855.9547 U4\U6 small nuclear ribonucleoprotein Prp3 OS=Homo sapiens OX=9606 GN=PRPF3 PE=1 SV=2 4.56 2671.4 - 255535 - - - -2.0732 - 2.264 0.599 - 198.2 1 2 0 -0.0035 15 0 0 0 3.63E+06 9.94E+05 - - - 5.4731 0.9985 221125_WJC_METTL3_EV_vs_WT_F07.15471.15471.4 0.00156 18/102 K.AIQDHLLEVEQSKDQMEK.E sp|P12270|TPR_HUMAN 1 2140.047 3.82 102349 15471 4 2140.04929 536.019 Nucleoprotein TPR OS=Homo sapiens OX=9606 GN=TPR PE=1 SV=3 4.5 2672.1 - 4.37E+06 - - - 1.0542 - 2.518 0.339 - 145.7 1 2 1 0.0023 18 0 0 0 2.62E+07 6.85E+06 - - - 2.4924 1 221125_WJC_METTL3_EV_vs_WT_F07.15472.15472.3 1.61E-12 31/68 K.AIQDHLLEVEQSKDQMEK.E sp|P12270|TPR_HUMAN 1 2140.047 4.9 102350 15472 3 2140.048157 714.3563 Nucleoprotein TPR OS=Homo sapiens OX=9606 GN=TPR PE=1 SV=3 4.5 2672.1 - 2.51E+06 - - - 0.5248 - 6.056 0.683 - 1456 1 2 1 0.0011 18 0 0 0 1.83E+07 3.73E+06 - - - 10.6393 1 221125_WJC_METTL3_EV_vs_WT_F07.15473.15473.3 2.31E-10 21/64 R.SLYTHSYEVPDHDNWPK.G sp|Q9BY49|PECR_HUMAN 1 2086.9385 2.17 102351 15473 3 2086.941529 696.6534 Peroxisomal trans-2-enoyl-CoA reductase OS=Homo sapiens OX=9606 GN=PECR PE=1 SV=2 5.2 2672.2 - 2.20E+06 - - - 1.4663 - 4.2 0.657 - 516.3 1 2 0 0.0031 17 0 0 0 1.80E+07 8.30E+06 - - - 9.4895 1 221125_WJC_METTL3_EV_vs_WT_F07.15474.15474.3 1.65E-06 18/40 K.TKPHLFYIPGR.M sp|Q9H307|PININ_HUMAN 1 1327.7401 1.92 102352 15474 3 1327.739931 443.5873 Pinin OS=Homo sapiens OX=9606 GN=PNN PE=1 SV=5 9.99 2672.3 - 2.04E+06 - - - -0.1205 - 3.059 0.545 - 473.1 1 2 0 -0.0002 11 0 0 0 2.09E+07 1.09E+07 - - - 7.7925 1 221125_WJC_METTL3_EV_vs_WT_F07.15475.15475.4 4.37E-12 23/114 R.K[136.11]PYPEDPAVYK[136.11]PLSQEELQR[166.11].L sp|O95628|CNOT4_HUMAN 1 2412.2535 2.08 102353 15475 4 2412.254077 604.0707 CCR4-NOT transcription complex subunit 4 OS=Homo sapiens OX=9606 GN=CNOT4 PE=1 SV=3 4.87 2672.4 - 2.00E+06 - - - 0.2201 - 4.248 0.649 - 401.7 1 2 0 0.0005 20 0 0 0 5.80E+07 2.79E+07 - - - 5.3583 1 221125_WJC_METTL3_EV_vs_WT_F07.15476.15476.3 1.27E-07 20/64 R.SLYTHSYEVPDHDNWPK[136.11].G sp|Q9BY49|PECR_HUMAN 1 2094.9527 2.17 102354 15476 3 2094.95516 699.3248 Peroxisomal trans-2-enoyl-CoA reductase OS=Homo sapiens OX=9606 GN=PECR PE=1 SV=2 5.2 2672.4 - 1.66E+06 - - - 1.189 - 3.288 0.608 - 442.3 1 2 0 0.0025 17 0 0 0 1.80E+07 8.30E+06 - - - 8.3249 1 221125_WJC_METTL3_EV_vs_WT_F07.15478.15478.3 1.55E-09 18/48 R.HTGYVIELQHVVK.G "sp|P47897|SYQ_HUMAN,tr|B4DDN1|B4DDN1_HUMAN,tr|H7C0R3|H7C0R3_HUMAN,tr|A0A0U1RQX5|A0A0U1RQX5_HUMAN,tr|A0A1B0GVU9|A0A1B0GVU9_HUMAN,tr|A0A0U1RQX9|A0A0U1RQX9_HUMAN,tr|A0A0U1RRC8|A0A0U1RRC8_HUMAN" 7 1521.8304 1.34 102356 15478 3 1521.831936 508.2841 Glutamine--tRNA ligase OS=Homo sapiens OX=9606 GN=QARS1 PE=1 SV=1 6.92 2672.6 - 1.27E+06 - - - 1.0336 - 3.115 0.591 - 530.5 1 2 0 0.0016 13 0 0 0 1.37E+07 1.02E+07 - - - 8.2093 1 221125_WJC_METTL3_EV_vs_WT_F07.15479.15479.3 2.81E-07 19/76 K.LLNGPGDVETGTSITVPQKK.W "sp|Q9HC07|TM165_HUMAN,tr|V9GY93|V9GY93_HUMAN" 2 2053.1055 1.13 102357 15479 3 2053.106154 685.3758 Transmembrane protein 165 OS=Homo sapiens OX=9606 GN=TMEM165 PE=1 SV=1 6.07 2672.7 - 1.21E+06 - - - 0.3015 - 3.529 0.593 - 280.4 1 2 0 0.0006 20 0 0 0 1.13E+07 9.99E+06 - - - 8.2104 1 221125_WJC_METTL3_EV_vs_WT_F07.15482.15482.3 4.65E-08 19/60 K.NQVALNPQNTVFDAK[136.11]R[166.11].L "sp|P0DMV8|HS71A_HUMAN,sp|P0DMV9|HS71B_HUMAN,tr|A0A0G2JIW1|A0A0G2JIW1_HUMAN" 3 1831.966 0.15 102360 15482 3 1831.968139 611.6626 Heat shock 70 kDa protein 1A OS=Homo sapiens OX=9606 GN=HSPA1A PE=1 SV=1 8.75 2673 - 978144 - - - 1.1867 - 3.526 0.472 - 561.5 1 2 0 0.0022 16 0 0 0 7.93E+07 5.47E+08 - - - 7.0351 1 221125_WJC_METTL3_EV_vs_WT_F07.15487.15487.4 3.22E-06 19/108 K.VKPQPPLSDAYLSGMPAKR.R "sp|P46379|BAG6_HUMAN,tr|A0A7I2V508|A0A7I2V508_HUMAN,tr|H0Y710|H0Y710_HUMAN,tr|H0Y4L1|H0Y4L1_HUMAN,tr|A0A7P0MQS5|A0A7P0MQS5_HUMAN,tr|A0A0G2JL47|A0A0G2JL47_HUMAN,tr|A0A024RCR6|A0A024RCR6_HUMAN,tr|A0A0G2JK23|A0A0G2JK23_HUMAN" 8 2054.0983 1.38 102365 15487 4 2054.100693 514.5318 Large proline-rich protein BAG6 OS=Homo sapiens OX=9606 GN=BAG6 PE=1 SV=2 9.7 2673.6 - 392547 - - - 1.1742 - 3.179 0.518 - 229.6 1 2 0 0.0024 19 0 0 0 5.73E+06 4.14E+06 - - - 4.1252 0.999 221125_WJC_METTL3_EV_vs_WT_F07.15488.15488.3 2.56E-05 16/64 R.LREEMEEITQQQLVHDK.Y sp|P42345|MTOR_HUMAN 1 2125.0474 -1 102366 15488 3 2125.039935 709.3564 Serine\threonine-protein kinase mTOR OS=Homo sapiens OX=9606 GN=MTOR PE=1 SV=1 4.57 2673.7 - 201647 - - - -3.4978 - 2.789 0.45 - 300 1 2 1 -0.0074 17 0 0 0 0.00E+00 0.00E+00 - - - 6.1462 1 221125_WJC_METTL3_EV_vs_WT_F07.15490.15490.3 0.000307 15/68 R.R[166.11]YSDHAGPAIPSVVAYPK[136.11].R "sp|P27448|MARK3_HUMAN,tr|A0A7I2V3C6|A0A7I2V3C6_HUMAN,tr|A0A7I2V3I9|A0A7I2V3I9_HUMAN,tr|H0YIY6|H0YIY6_HUMAN,tr|A0A7I2V3P5|A0A7I2V3P5_HUMAN,tr|A0A7I2V5G3|A0A7I2V5G3_HUMAN,tr|A0A7I2YQF7|A0A7I2YQF7_HUMAN,tr|A0A7I2V4K8|A0A7I2V4K8_HUMAN,tr|A0A7I2V3K2|A0A7I2V3K2_HUMAN,tr|A0A7I2V2U9|A0A7I2V2U9_HUMAN,tr|A0A7I2V4G7|A0A7I2V4G7_HUMAN,tr|H0YNV4|H0YNV4_HUMAN,tr|A0A7I2V2N8|A0A7I2V2N8_HUMAN,tr|H0YJI9|H0YJI9_HUMAN,tr|A0A7I2V409|A0A7I2V409_HUMAN,tr|A0A7I2V4T2|A0A7I2V4T2_HUMAN,tr|A0A7I2V3B9|A0A7I2V3B9_HUMAN,tr|A0A7I2V639|A0A7I2V639_HUMAN,tr|A0A7I2V2E3|A0A7I2V2E3_HUMAN,tr|A0A7I2V2I9|A0A7I2V2I9_HUMAN,tr|J3KNR0|J3KNR0_HUMAN,tr|H0YKP9|H0YKP9_HUMAN" 22 1945.0177 1.86 102368 15490 3 1945.019959 649.3465 MAP\microtubule affinity-regulating kinase 3 OS=Homo sapiens OX=9606 GN=MARK3 PE=1 SV=5 8.5 2674 - 185878 - - - 1.1789 - 3.183 0.508 - 314.1 1 2 0 0.0023 18 0 0 0 2.91E+06 1.56E+06 - - - 7.0862 0.9989 221125_WJC_METTL3_EV_vs_WT_F07.15492.15492.2 0.0248 May-34 K.TSSSSPANSDVEIDGIGR.L sp|O60293|ZC3H1_HUMAN 1 1790.8283 2.34 102369 15492 2 1790.823848 896.4214 Zinc finger C3H1 domain-containing protein OS=Homo sapiens OX=9606 GN=ZFC3H1 PE=1 SV=3 4.03 2674.2 - 0 - - - -2.4581 - 1.099 0.555 - 47.1 1 2 0 -0.0044 18 0 0 0 2.24E+06 9.58E+05 - - - 3.3709 0.9996 221125_WJC_METTL3_EV_vs_WT_F07.15496.15496.4 0.000246 25/120 R.GLELLAASEAPRDPPGQAKPR.G "sp|Q86WX3|AROS_HUMAN,tr|F8WFE7|F8WFE7_HUMAN" 2 2172.1651 1.6 102372 15496 4 2172.170331 544.0486 Active regulator of SIRT1 OS=Homo sapiens OX=9606 GN=RPS19BP1 PE=1 SV=1 6.18 2674.6 - 1.30E+06 - - - 2.4013 - 3.583 0.464 - 663.2 1 2 1 0.0052 21 0 0 0 2.42E+07 1.51E+07 - - - 3.6852 1 221125_WJC_METTL3_EV_vs_WT_F07.15497.15497.3 8.45E-07 15/48 R.HTGYVIELQHVVK[136.11].G "sp|P47897|SYQ_HUMAN,tr|B4DDN1|B4DDN1_HUMAN,tr|H7C0R3|H7C0R3_HUMAN,tr|A0A0U1RQX5|A0A0U1RQX5_HUMAN,tr|A0A1B0GVU9|A0A1B0GVU9_HUMAN,tr|A0A0U1RQX9|A0A0U1RQX9_HUMAN,tr|A0A0U1RRC8|A0A0U1RRC8_HUMAN" 7 1529.8446 1.35 102373 15497 3 1529.848928 510.9555 Glutamine--tRNA ligase OS=Homo sapiens OX=9606 GN=QARS1 PE=1 SV=1 6.92 2674.7 - 980328 - - - 2.8532 - 3.001 0.56 - 303.8 1 2 0 0.0044 13 0 0 0 1.35E+07 1.00E+07 - - - 7.7618 0.9999 221125_WJC_METTL3_EV_vs_WT_F07.15498.15498.3 7.00E-05 15/56 R.QAAVGQGDFHLLDHR[166.11].G "sp|O43819|SCO2_HUMAN,tr|A0A1W2PQK0|A0A1W2PQK0_HUMAN" 2 1672.8309 1.07 102374 15498 3 1672.825964 558.6176 "Protein SCO2 homolog, mitochondrial OS=Homo sapiens OX=9606 GN=SCO2 PE=1 SV=3" 5.98 2674.8 - 898406 - - - -2.9638 - 2.711 0.457 - 209.8 1 2 0 -0.005 15 0 0 0 4.13E+07 3.88E+07 - - - 6.2361 1 221125_WJC_METTL3_EV_vs_WT_F07.15500.15500.4 9.85E-07 14/84 R.EYWMDPEGEMK[136.11]PGR[166.11]K[136.11].G sp|P53999|TCP4_HUMAN 1 1877.8651 4.61 102376 15500 4 1877.868894 470.4735 Activated RNA polymerase II transcriptional coactivator p15 OS=Homo sapiens OX=9606 GN=SUB1 PE=1 SV=3 4.87 2675 - 471840 - - - 2.0417 - 2.528 0.546 - 122.4 1 2 0 0.0038 15 0 0 0 6.48E+07 1.41E+07 - - - 4.3092 1 221125_WJC_METTL3_EV_vs_WT_F07.15504.15504.3 1.75E-07 Sep-96 K.EGVILTNESAASTGQPDNDVTEGQR.A sp|Q08J23|NSUN2_HUMAN 1 2587.1998 0.89 102380 15504 3 2587.200856 863.4072 RNA cytosine C(5)-methyltransferase NSUN2 OS=Homo sapiens OX=9606 GN=NSUN2 PE=1 SV=2 3.83 2675.6 - 159198 - - - 0.4151 - 2.219 0.608 - 56.4 1 2 0 0.0011 25 0 0 0 1.08E+06 1.22E+06 - - - 7.152 0.9998 221125_WJC_METTL3_EV_vs_WT_F07.15508.15508.4 4.61E-11 22/120 R.GLELLAASEAPR[166.11]DPPGQAK[136.11]PR[166.11].G "sp|Q86WX3|AROS_HUMAN,tr|F8WFE7|F8WFE7_HUMAN" 2 2200.1959 1.6 102382 15508 4 2200.201702 551.0562 Active regulator of SIRT1 OS=Homo sapiens OX=9606 GN=RPS19BP1 PE=1 SV=1 6.18 2676.1 - 1.43E+06 - - - 2.6575 - 3.702 0.542 - 502.1 1 2 1 0.0058 21 0 0 0 2.42E+07 1.51E+07 - - - 4.3747 0.9998 221125_WJC_METTL3_EV_vs_WT_F07.15509.15509.3 2.41E-06 18/80 R.GLELLAASEAPRDPPGQAKPR.G "sp|Q86WX3|AROS_HUMAN,tr|F8WFE7|F8WFE7_HUMAN" 2 2172.1651 2.13 102383 15509 3 2172.165842 725.0623 Active regulator of SIRT1 OS=Homo sapiens OX=9606 GN=RPS19BP1 PE=1 SV=1 6.18 2676.2 - 673080 - - - 0.3347 - 3.296 0.4 - 379.6 1 2 1 0.0007 21 0 0 0 7.60E+06 3.57E+06 - - - 5.8589 0.9999 221125_WJC_METTL3_EV_vs_WT_F07.15510.15510.3 4.43E-09 28/96 R.AGAPGIQEAEVSAAQGTTGTAPGAR.A sp|Q9H0W5|CCDC8_HUMAN 1 2267.1142 1.4 102384 15510 3 2267.124746 756.712 Coiled-coil domain-containing protein 8 OS=Homo sapiens OX=9606 GN=CCDC8 PE=1 SV=2 4.53 2676.3 - 1.76E+06 - - - 4.6508 - 4.552 0.577 - 867.5 1 2 0 0.0105 25 0 0 0 1.71E+07 1.22E+07 - - - 8.4568 0.9999 221125_WJC_METTL3_EV_vs_WT_F07.15511.15511.4 4.55E-06 16/84 K.C[160.03]WIADNR[166.11]PSVEFHER[166.11].G sp|O75554|WBP4_HUMAN 1 1934.8961 0.67 102385 15511 4 1934.899227 484.7313 WW domain-binding protein 4 OS=Homo sapiens OX=9606 GN=WBP4 PE=1 SV=1 5.45 2676.4 - 643756 - - - 1.6394 - 3.099 0.463 - 273.7 1 2 0 0.0032 15 0 0 0 2.58E+06 3.83E+06 - - - 3.6598 0.9986 221125_WJC_METTL3_EV_vs_WT_F07.15513.15513.4 0.00155 13/84 K.C[160.03]WIADNRPSVEFHER.G sp|O75554|WBP4_HUMAN 1 1914.8795 0.66 102387 15513 4 1914.887198 479.7272 WW domain-binding protein 4 OS=Homo sapiens OX=9606 GN=WBP4 PE=1 SV=1 5.45 2676.6 - 435417 - - - 4.0123 - 2.388 0.371 - 159.6 1 2 0 0.0077 15 0 0 0 2.58E+06 3.92E+06 - - - 2.7645 0.9985 221125_WJC_METTL3_EV_vs_WT_F07.15514.15514.3 0.00148 Nov-68 K.EAGELK[136.11]PEEEITVGPVQK[136.11].L sp|P53618|COPB_HUMAN 1 1968.0386 0.47 102388 15514 3 1968.046446 657.0202 Coatomer subunit beta OS=Homo sapiens OX=9606 GN=COPB1 PE=1 SV=3 4.33 2676.8 - 415809 - - - 3.9679 - 2.307 0.355 - 126.6 1 2 0 0.0078 18 0 0 0 6.24E+05 1.32E+06 - - - 4.5773 0.9942 221125_WJC_METTL3_EV_vs_WT_F07.15516.15516.3 0.00636 Oct-72 K.NETGGGEGIEVLKNEPYEK.D "sp|P48739|PIPNB_HUMAN,tr|B3KYB7|B3KYB7_HUMAN,tr|A0A0A0MSW4|A0A0A0MSW4_HUMAN" 3 2061.9855 2.96 102390 15516 3 2061.988873 688.3358 Phosphatidylinositol transfer protein beta isoform OS=Homo sapiens OX=9606 GN=PITPNB PE=1 SV=2 4.33 2677 - 366495 - - - 1.646 - 2.272 0.261 - 134 1 2 1 0.0034 19 0 0 0 5.24E+06 1.77E+06 - - - 3.4652 0.9996 221125_WJC_METTL3_EV_vs_WT_F07.15526.15526.3 1.61E-07 20/80 R.VVNTDHGSPEQLQIPVTDSGR[166.11].H sp|Q6IQ49|SDE2_HUMAN 1 2258.1167 0.87 102398 15526 3 2258.128869 753.7128 Replication stress response regulator SDE2 OS=Homo sapiens OX=9606 GN=SDE2 PE=1 SV=1 4.54 2678.3 - 960903 - - - 5.4076 - 3.4 0.506 - 281 1 2 0 0.0122 21 0 0 0 7.64E+06 8.81E+06 - - - 7.112 1 221125_WJC_METTL3_EV_vs_WT_F07.15527.15527.3 1.45E-10 20/80 R.VTGDHVDLTTC[160.03]PLAAGAQQEK.L sp|Q15828|CYTM_HUMAN 1 2210.0637 999 102399 15527 3 2210.068106 737.6952 Cystatin-M OS=Homo sapiens OX=9606 GN=CST6 PE=1 SV=1 4.54 2678.5 - 659112 - - - 1.9723 - 3.434 0.563 - 450 1 2 0 0.0044 21 0 0 0 8.43E+06 0.00E+00 - - - 7.7735 1 221125_WJC_METTL3_EV_vs_WT_F07.15530.15530.3 2.60E-09 18/60 K.YTVQDESHSEWVSC[160.03]VR[166.11].F "sp|P63244|RACK1_HUMAN,tr|H0YAM7|H0YAM7_HUMAN,tr|D6RFX4|D6RFX4_HUMAN,tr|D6RFZ9|D6RFZ9_HUMAN,tr|H0YAF8|H0YAF8_HUMAN,tr|D6R9Z1|D6R9Z1_HUMAN,tr|J3KPE3|J3KPE3_HUMAN,tr|D6R9L0|D6R9L0_HUMAN,tr|D6RHH4|D6RHH4_HUMAN,tr|D6RBD0|D6RBD0_HUMAN,tr|H0Y8W2|H0Y8W2_HUMAN" 11 1990.8719 1.64 102402 15530 3 1990.873261 664.6312 Receptor of activated protein C kinase 1 OS=Homo sapiens OX=9606 GN=RACK1 PE=1 SV=3 4.65 2678.8 - 456875 - - - 0.7037 - 3.213 0.673 - 540.3 1 2 0 0.0014 16 0 0 0 5.85E+06 3.57E+06 - - - 9.0378 0.9999 221125_WJC_METTL3_EV_vs_WT_F07.15531.15531.3 0.000246 17/80 R.GLELLAASEAPR[166.11]DPPGQAK[136.11]PR[166.11].G "sp|Q86WX3|AROS_HUMAN,tr|F8WFE7|F8WFE7_HUMAN" 2 2200.1959 2.13 102403 15531 3 2200.198723 734.4059 Active regulator of SIRT1 OS=Homo sapiens OX=9606 GN=RPS19BP1 PE=1 SV=1 6.18 2679 - 452575 - - - 1.3035 - 3.339 0.51 - 305.2 1 2 1 0.0029 21 0 0 0 7.60E+06 3.57E+06 - - - 7.1157 0.9931 221125_WJC_METTL3_EV_vs_WT_F07.15535.15535.3 0.00164 Sep-92 K.QPGPVTNGQLQQPTTGAASGGYIK.R "sp|O00161|SNP23_HUMAN,tr|H3BP15|H3BP15_HUMAN,tr|H3BQY9|H3BQY9_HUMAN,tr|H3BV99|H3BV99_HUMAN" 4 2369.1975 0.76 102407 15535 3 2369.206872 790.7398 Synaptosomal-associated protein 23 OS=Homo sapiens OX=9606 GN=SNAP23 PE=1 SV=1 8.59 2679.5 - 184287 - - - 3.9397 - 1.793 0.313 - 52 1 2 0 0.0093 24 0 0 0 2.75E+06 3.61E+06 - - - 3.3832 0.9935 221125_WJC_METTL3_EV_vs_WT_F07.15539.15539.3 2.48E-06 16/80 Q.STGPSEPGAFQPPPKPVIVDK.H "sp|P49406|RM19_HUMAN,tr|A0A0A0MRF4|A0A0A0MRF4_HUMAN" 2 2147.1263 1.21 102409 15539 3 2147.132092 716.716 "39S ribosomal protein L19, mitochondrial OS=Homo sapiens OX=9606 GN=MRPL19 PE=1 SV=2" 5.79 2679.9 - 1.56E+06 - - - 2.7115 - 2.77 0.546 - 169.1 1 1 0 0.0058 21 0 0 0 2.29E+07 1.89E+07 - - - 7.0684 1 221125_WJC_METTL3_EV_vs_WT_F07.15540.15540.3 1.11E-09 16/36 K.DHHFDMINIK[136.11].S sp|Q9P032|NDUF4_HUMAN 1 1276.6114 1.3 102410 15540 3 1276.612603 426.5444 NADH dehydrogenase [ubiquinone] 1 alpha subcomplex assembly factor 4 OS=Homo sapiens OX=9606 GN=NDUFAF4 PE=1 SV=1 5.98 2680 - 1.02E+06 - - - 0.9486 - 2.959 0.683 - 492.9 1 2 0 0.0012 10 0 0 0 1.34E+07 1.03E+07 - - - 9.3227 1 221125_WJC_METTL3_EV_vs_WT_F07.15542.15542.3 6.08E-10 18/88 R.VTTVASHTSDSDVPSGVTEVVVK.L "sp|P10909|CLUS_HUMAN,tr|H0YAS8|H0YAS8_HUMAN,tr|H0YC35|H0YC35_HUMAN" 3 2313.17 262.07 102412 15542 3 2313.175296 772.0639 Clusterin OS=Homo sapiens OX=9606 GN=CLU PE=1 SV=1 4.54 2680.2 - 676948 - - - 2.2956 - 3.033 0.618 - 302.4 1 2 0 0.0053 23 0 0 0 1.63E+07 6.21E+04 - - - 8.0316 0.999 221125_WJC_METTL3_EV_vs_WT_F07.15543.15543.2 0.000341 16-Nov K.VGLQVVAVK.A "sp|P10809|CH60_HUMAN,tr|A0A7I2V2X6|A0A7I2V2X6_HUMAN,tr|A0A7I2YQK6|A0A7I2YQK6_HUMAN,tr|A0A7I2V599|A0A7I2V599_HUMAN,tr|A0A7I2V5M1|A0A7I2V5M1_HUMAN" 5 911.5804 1.22 102413 15543 2 911.582478 456.7975 "60 kDa heat shock protein, mitochondrial OS=Homo sapiens OX=9606 GN=HSPD1 PE=1 SV=2" 8.72 2680.4 - 631504 - - - 2.2763 - 2.233 0.266 - 343.5 1 2 0 0.0021 9 0 0 0 5.82E+06 4.79E+06 - - - 3.3291 0.9986 221125_WJC_METTL3_EV_vs_WT_F07.15547.15547.2 0.000505 16-Sep K.VGLQVVAVK[136.11].A "sp|P10809|CH60_HUMAN,tr|A0A7I2V2X6|A0A7I2V2X6_HUMAN,tr|A0A7I2YQK6|A0A7I2YQK6_HUMAN,tr|A0A7I2V599|A0A7I2V599_HUMAN,tr|A0A7I2V5M1|A0A7I2V5M1_HUMAN" 5 919.5946 1.22 102417 15547 2 919.596493 460.8046 "60 kDa heat shock protein, mitochondrial OS=Homo sapiens OX=9606 GN=HSPD1 PE=1 SV=2" 8.72 2680.9 - 499479 - - - 2.0553 - 2.014 0.246 - 179.4 1 2 0 0.0019 9 0 0 0 5.82E+06 4.79E+06 - - - 2.8829 0.9999 221125_WJC_METTL3_EV_vs_WT_F07.15548.15548.4 6.78E-05 15/84 K.AFIAHFQDNLHSVNR[166.11].D "sp|Q6P2C8|MED27_HUMAN,tr|A0A494C0P0|A0A494C0P0_HUMAN,tr|A0A494C0K7|A0A494C0K7_HUMAN" 3 1777.8888 1.48 102418 15548 4 1777.889477 445.4795 Mediator of RNA polymerase II transcription subunit 27 OS=Homo sapiens OX=9606 GN=MED27 PE=1 SV=1 6.96 2681 - 438397 - - - 0.3971 - 2.311 0.395 - 92.1 1 2 0 0.0007 15 0 0 0 3.15E+06 2.13E+06 - - - 2.9636 0.9999 221125_WJC_METTL3_EV_vs_WT_F07.15554.15554.3 6.24E-05 13/92 K.QPGPVTNGQLQQPTTGAASGGYIK[136.11].R "sp|O00161|SNP23_HUMAN,tr|H3BP15|H3BP15_HUMAN,tr|H3BQY9|H3BQY9_HUMAN,tr|H3BV99|H3BV99_HUMAN" 4 2377.2117 0.76 102424 15554 3 2377.21656 793.4112 Synaptosomal-associated protein 23 OS=Homo sapiens OX=9606 GN=SNAP23 PE=1 SV=1 8.59 2681.8 - 192834 - - - 2.0284 - 2.815 0.445 - 133 1 2 0 0.0048 24 0 0 0 2.75E+06 3.61E+06 - - - 5.9038 1 221125_WJC_METTL3_EV_vs_WT_F07.15560.15560.4 0.0004 22/102 R.VIAPSSSLPTSLTIHHPR.E sp|Q02413|DSG1_HUMAN 1 1912.053 999 102428 15560 4 1912.055205 479.0205 Desmoglein-1 OS=Homo sapiens OX=9606 GN=DSG1 PE=1 SV=2 9.73 2682.6 - 1.89E+06 - - - 1.1292 - 3.907 0.537 - 586.2 1 2 0 0.0022 18 0 0 0 2.36E+07 0.00E+00 - - - 4.3663 0.9999 221125_WJC_METTL3_EV_vs_WT_F07.15561.15561.4 4.26E-09 16/96 K.AGKFPSLLTHNENMVAK.V sp|P62906|RL10A_HUMAN 1 1855.9615 0.95 102429 15561 4 1855.965213 464.9976 60S ribosomal protein L10a OS=Homo sapiens OX=9606 GN=RPL10A PE=1 SV=2 8.64 2682.6 - 2.10E+06 - - - 2.0259 - 3.688 0.585 - 164.2 1 2 1 0.0038 17 0 0 0 4.19E+07 4.42E+07 - - - 4.7699 1 221125_WJC_METTL3_EV_vs_WT_F07.15562.15562.4 1.54E-05 24/120 R.VLAGQTLDINMAGEPK[136.11]PDR[166.11]PK[136.11].G "sp|Q9UKM9|RALY_HUMAN,tr|Q5QPM1|Q5QPM1_HUMAN,tr|Q5QPL9|Q5QPL9_HUMAN" 3 2275.2205 1.26 102430 15562 4 2275.224834 569.8124 RNA-binding protein Raly OS=Homo sapiens OX=9606 GN=RALY PE=1 SV=1 6.09 2682.8 - 1.19E+06 - - - 1.9172 - 4.227 0.545 - 472.9 1 2 0 0.0044 21 0 0 0 1.28E+08 1.02E+08 - - - 4.4451 0.9966 221125_WJC_METTL3_EV_vs_WT_F07.15563.15563.3 5.45E-06 19/80 Q.STGPSEPGAFQPPPK[136.11]PVIVDK[136.11].H "sp|P49406|RM19_HUMAN,tr|A0A0A0MRF4|A0A0A0MRF4_HUMAN" 2 2163.1547 1.21 102431 15563 3 2163.159665 722.0588 "39S ribosomal protein L19, mitochondrial OS=Homo sapiens OX=9606 GN=MRPL19 PE=1 SV=2" 5.79 2682.9 - 963834 - - - 2.3091 - 3.15 0.573 - 241.5 1 1 0 0.005 21 0 0 0 2.29E+07 1.89E+07 - - - 7.6778 0.8919 221125_WJC_METTL3_EV_vs_WT_F07.15567.15567.4 0.000778 10/102 K.VGGAEGTKLDDDFKEMEK.K sp|Q99961|SH3G1_HUMAN 1 1967.9146 1.41 102435 15567 4 1967.927313 492.9859 Endophilin-A2 OS=Homo sapiens OX=9606 GN=SH3GL1 PE=1 SV=1 4.3 2683.4 - 340027 - - - 6.4485 - 2.057 0.33 - 51.7 2 2 2 0.0127 18 0 0 0 4.50E+06 3.20E+06 - - - 2.1124 0.9961 221125_WJC_METTL3_EV_vs_WT_F07.15568.15568.3 0.0039 Oct-36 K.QNRPIPQWIR.M "sp|P62891|RL39_HUMAN,sp|Q59GN2|R39L5_HUMAN" 2 1306.7258 0.6 102436 15568 3 1306.72691 436.5826 60S ribosomal protein L39 OS=Homo sapiens OX=9606 GN=RPL39 PE=1 SV=2 12 2683.5 - 238701 - - - 0.8204 - 1.897 0.179 - 128.6 1 2 0 0.0011 10 0 0 0 6.54E+06 1.09E+07 - - - 2.4053 1 221125_WJC_METTL3_EV_vs_WT_F07.15569.15569.3 4.51E-09 14/92 R.VLR[166.11]PQVTAVAQQNQGEVPEPQDMK[136.11].V "sp|Q14204|DYHC1_HUMAN,tr|A0A7P0T8N2|A0A7P0T8N2_HUMAN,tr|A0A7P0T9C4|A0A7P0T9C4_HUMAN,tr|A0A7P0TBJ7|A0A7P0TBJ7_HUMAN,tr|A0A804HHY6|A0A804HHY6_HUMAN,tr|A0A7P0T9K2|A0A7P0T9K2_HUMAN,tr|A0A7P0TB64|A0A7P0TB64_HUMAN,tr|A0A2R8Y706|A0A2R8Y706_HUMAN,tr|A0A7P0T916|A0A7P0T916_HUMAN,tr|A0A7P0TB75|A0A7P0TB75_HUMAN,tr|A0A7P0T8W5|A0A7P0T8W5_HUMAN,tr|A0A7P0T9S3|A0A7P0T9S3_HUMAN,tr|A0A7P0TAF3|A0A7P0TAF3_HUMAN,tr|A0A7P0T9F1|A0A7P0T9F1_HUMAN,tr|A0A7P0TAW9|A0A7P0TAW9_HUMAN,tr|A0A2R8YGC7|A0A2R8YGC7_HUMAN,tr|A0A7P0TA13|A0A7P0TA13_HUMAN,tr|A0A7P0T934|A0A7P0T934_HUMAN,tr|A0A7P0TAV5|A0A7P0TAV5_HUMAN,tr|A0A7P0T9Y3|A0A7P0T9Y3_HUMAN,tr|A0A7P0T7V5|A0A7P0T7V5_HUMAN,tr|A0A7P0T9R4|A0A7P0T9R4_HUMAN,tr|A0A2R8Y5T0|A0A2R8Y5T0_HUMAN,tr|A0A7P0T990|A0A7P0T990_HUMAN,tr|A0A7P0T942|A0A7P0T942_HUMAN,tr|A0A2R8YFZ7|A0A2R8YFZ7_HUMAN,tr|A0A7P0T825|A0A7P0T825_HUMAN,tr|A0A2R8Y6H2|A0A2R8Y6H2_HUMAN,tr|A0A7P0TBC9|A0A7P0TBC9_HUMAN,tr|A0A7P0TAM4|A0A7P0TAM4_HUMAN" 30 2679.3769 2.04 102437 15569 3 2679.3763 894.1329 Cytoplasmic dynein 1 heavy chain 1 OS=Homo sapiens OX=9606 GN=DYNC1H1 PE=1 SV=5 4.68 2683.7 - 160985 - - - -0.231 - 2.78 0.669 - 135.3 1 2 0 -0.0006 24 0 0 0 9.59E+06 4.70E+06 - - - 8.3733 0.9992 221125_WJC_METTL3_EV_vs_WT_F07.15570.15570.3 0.000177 Aug-64 K.K[136.11]EGK[136.11]PTIVEEDDPELFK[136.11].Q sp|O75937|DNJC8_HUMAN 1 1997.0419 3.55 102438 15570 3 1997.049179 666.6879 DnaJ homolog subfamily C member 8 OS=Homo sapiens OX=9606 GN=DNAJC8 PE=1 SV=2 4.36 2683.8 - 152811 - - - 3.6259 - 1.934 0.427 - 74.7 1 2 0 0.0072 17 0 0 0 9.76E+06 2.75E+06 - - - 4.9649 1 221125_WJC_METTL3_EV_vs_WT_F07.15573.15573.3 3.15E-13 23/60 K.GHFGPINSVAFHPDGK.S "sp|Q13347|EIF3I_HUMAN,tr|A0A7I2YQT9|A0A7I2YQT9_HUMAN,tr|A0A7I2V613|A0A7I2V613_HUMAN,tr|A0A7I2V3N2|A0A7I2V3N2_HUMAN,tr|A0A7I2YQU2|A0A7I2YQU2_HUMAN,tr|A0A7I2YQF8|A0A7I2YQF8_HUMAN,tr|A0A7I2V3U3|A0A7I2V3U3_HUMAN,tr|A0A7I2V607|A0A7I2V607_HUMAN,tr|A0A7I2V640|A0A7I2V640_HUMAN,tr|A0A7P0MRT9|A0A7P0MRT9_HUMAN,tr|A0A7I2V5V8|A0A7I2V5V8_HUMAN,tr|A0A7I2V2M3|A0A7I2V2M3_HUMAN,tr|A0A7I2V4C2|A0A7I2V4C2_HUMAN,tr|A0A7I2YQI2|A0A7I2YQI2_HUMAN,tr|A0A7I2YQC8|A0A7I2YQC8_HUMAN,tr|A0A7I2V685|A0A7I2V685_HUMAN" 16 1678.8216 1.42 102439 15573 3 1678.822376 560.6145 Eukaryotic translation initiation factor 3 subunit I OS=Homo sapiens OX=9606 GN=EIF3I PE=1 SV=1 6.92 2684.2 - 2.74E+06 - - - 0.4688 - 3.991 0.661 - 753.6 1 2 0 0.0008 16 0 0 0 5.94E+07 4.20E+07 - - - 9.4605 0.9999 221125_WJC_METTL3_EV_vs_WT_F07.15574.15574.3 1.52E-08 18/64 K.AGK[136.11]FPSLLTHNENMVAK[136.11].V sp|P62906|RL10A_HUMAN 1 1871.9899 0.81 102440 15574 3 1871.991287 625.0039 60S ribosomal protein L10a OS=Homo sapiens OX=9606 GN=RPL10A PE=1 SV=2 8.64 2684.2 - 2.21E+06 - - - 0.766 - 3.018 0.575 - 214.4 1 2 1 0.0014 17 0 0 0 2.11E+07 2.60E+07 - - - 7.7408 1 221125_WJC_METTL3_EV_vs_WT_F07.15575.15575.4 2.01E-08 19/90 K.GHFGPINSVAFHPDGK[136.11].S "sp|Q13347|EIF3I_HUMAN,tr|A0A7I2YQT9|A0A7I2YQT9_HUMAN,tr|A0A7I2V613|A0A7I2V613_HUMAN,tr|A0A7I2V3N2|A0A7I2V3N2_HUMAN,tr|A0A7I2YQU2|A0A7I2YQU2_HUMAN,tr|A0A7I2YQF8|A0A7I2YQF8_HUMAN,tr|A0A7I2V3U3|A0A7I2V3U3_HUMAN,tr|A0A7I2V607|A0A7I2V607_HUMAN,tr|A0A7I2V640|A0A7I2V640_HUMAN,tr|A0A7P0MRT9|A0A7P0MRT9_HUMAN,tr|A0A7I2V5V8|A0A7I2V5V8_HUMAN,tr|A0A7I2V2M3|A0A7I2V2M3_HUMAN,tr|A0A7I2V4C2|A0A7I2V4C2_HUMAN,tr|A0A7I2YQI2|A0A7I2YQI2_HUMAN,tr|A0A7I2YQC8|A0A7I2YQC8_HUMAN,tr|A0A7I2V685|A0A7I2V685_HUMAN" 16 1686.8358 1.19 102441 15575 4 1686.83705 422.7162 Eukaryotic translation initiation factor 3 subunit I OS=Homo sapiens OX=9606 GN=EIF3I PE=1 SV=1 6.92 2684.3 - 2.39E+06 - - - 0.7476 - 2.942 0.583 - 375.8 1 2 0 0.0013 16 0 0 0 5.10E+07 4.29E+07 - - - 4.6802 0.9992 221125_WJC_METTL3_EV_vs_WT_F07.15576.15576.3 1.69E-05 15/64 K.AGKFPSLLTHNENMVAK.V sp|P62906|RL10A_HUMAN 1 1855.9615 0.81 102442 15576 3 1855.968535 619.6611 60S ribosomal protein L10a OS=Homo sapiens OX=9606 GN=RPL10A PE=1 SV=2 8.64 2684.4 - 2.08E+06 - - - 3.8158 - 2.832 0.502 - 148.2 1 2 1 0.0071 17 0 0 0 2.07E+07 2.55E+07 - - - 6.7647 1 221125_WJC_METTL3_EV_vs_WT_F07.15578.15578.3 4.68E-05 16/68 R.VIAPSSSLPTSLTIHHPR.E sp|Q02413|DSG1_HUMAN 1 1912.053 999 102444 15578 3 1912.055656 638.3583 Desmoglein-1 OS=Homo sapiens OX=9606 GN=DSG1 PE=1 SV=2 9.73 2684.5 - 814935 - - - 1.365 - 2.947 0.484 - 295 1 2 0 0.0026 18 0 0 0 5.81E+06 0.00E+00 - - - 6.6267 0.9999 221125_WJC_METTL3_EV_vs_WT_F07.15580.15580.3 0.000233 15/36 K.QNR[166.11]PIPQWIR[166.11].M "sp|P62891|RL39_HUMAN,sp|Q59GN2|R39L5_HUMAN" 2 1326.7424 0.63 102446 15580 3 1326.744532 443.2547 60S ribosomal protein L39 OS=Homo sapiens OX=9606 GN=RPL39 PE=1 SV=2 12 2684.8 - 733933 - - - 1.6235 - 2.368 0.43 - 467.8 1 2 0 0.0022 10 0 0 0 6.54E+06 1.03E+07 - - - 5.851 0.9999 221125_WJC_METTL3_EV_vs_WT_F07.15581.15581.3 7.07E-06 14/52 R.NLDIERPTYTNLNR.L "sp|Q9NY65|TBA8_HUMAN,sp|Q6PEY2|TBA3E_HUMAN,sp|P0DPH7|TBA3C_HUMAN,sp|Q71U36|TBA1A_HUMAN,sp|P0DPH8|TBA3D_HUMAN,sp|Q9H853|TBA4B_HUMAN,sp|P68366|TBA4A_HUMAN,sp|P68363|TBA1B_HUMAN,sp|Q9BQE3|TBA1C_HUMAN,tr|F8VVB9|F8VVB9_HUMAN,tr|C9JDS9|C9JDS9_HUMAN,tr|A0A7P0TA31|A0A7P0TA31_HUMAN,tr|F5H5D3|F5H5D3_HUMAN,tr|C9J2C0|C9J2C0_HUMAN,tr|F8VQQ4|F8VQQ4_HUMAN,tr|A0A7P0T945|A0A7P0T945_HUMAN" 16 1717.8747 0.92 102447 15581 3 1717.877955 573.6322 Tubulin alpha-8 chain OS=Homo sapiens OX=9606 GN=TUBA8 PE=1 SV=1 6.07 2684.9 - 677647 - - - 1.8674 - 2.53 0.396 - 263.7 1 2 0 0.0032 14 0 0 0 1.76E+07 1.92E+07 - - - 5.4209 1 221125_WJC_METTL3_EV_vs_WT_F07.15582.15582.3 2.83E-09 17/80 R.VLAGQTLDINMAGEPK[136.11]PDR[166.11]PK[136.11].G "sp|Q9UKM9|RALY_HUMAN,tr|Q5QPM1|Q5QPM1_HUMAN,tr|Q5QPL9|Q5QPL9_HUMAN" 3 2275.2205 3.31 102448 15582 3 2275.220406 759.4141 RNA-binding protein Raly OS=Homo sapiens OX=9606 GN=RALY PE=1 SV=1 6.09 2685 - 395819 - - - -0.029 - 3.783 0.591 - 303.8 1 2 0 -0.0001 21 0 0 0 4.15E+07 1.25E+07 - - - 8.3189 0.9999 221125_WJC_METTL3_EV_vs_WT_F07.15587.15587.3 3.17E-06 14/52 R.NLDIER[166.11]PTYTNLNR[166.11].L "sp|Q9NY65|TBA8_HUMAN,sp|Q6PEY2|TBA3E_HUMAN,sp|P0DPH7|TBA3C_HUMAN,sp|Q71U36|TBA1A_HUMAN,sp|P0DPH8|TBA3D_HUMAN,sp|Q9H853|TBA4B_HUMAN,sp|P68366|TBA4A_HUMAN,sp|P68363|TBA1B_HUMAN,sp|Q9BQE3|TBA1C_HUMAN,tr|F8VVB9|F8VVB9_HUMAN,tr|C9JDS9|C9JDS9_HUMAN,tr|A0A7P0TA31|A0A7P0TA31_HUMAN,tr|F5H5D3|F5H5D3_HUMAN,tr|C9J2C0|C9J2C0_HUMAN,tr|F8VQQ4|F8VQQ4_HUMAN,tr|A0A7P0T945|A0A7P0T945_HUMAN" 16 1737.8913 0.88 102451 15587 3 1737.895036 580.3044 Tubulin alpha-8 chain OS=Homo sapiens OX=9606 GN=TUBA8 PE=1 SV=1 6.07 2685.7 - 1.71E+06 - - - 2.1572 - 2.481 0.452 - 244.7 1 2 0 0.0037 14 0 0 0 1.69E+07 1.92E+07 - - - 5.9931 1 221125_WJC_METTL3_EV_vs_WT_F07.15589.15589.4 3.66E-06 19/90 K.GHFGPINSVAFHPDGK.S "sp|Q13347|EIF3I_HUMAN,tr|A0A7I2YQT9|A0A7I2YQT9_HUMAN,tr|A0A7I2V613|A0A7I2V613_HUMAN,tr|A0A7I2V3N2|A0A7I2V3N2_HUMAN,tr|A0A7I2YQU2|A0A7I2YQU2_HUMAN,tr|A0A7I2YQF8|A0A7I2YQF8_HUMAN,tr|A0A7I2V3U3|A0A7I2V3U3_HUMAN,tr|A0A7I2V607|A0A7I2V607_HUMAN,tr|A0A7I2V640|A0A7I2V640_HUMAN,tr|A0A7P0MRT9|A0A7P0MRT9_HUMAN,tr|A0A7I2V5V8|A0A7I2V5V8_HUMAN,tr|A0A7I2V2M3|A0A7I2V2M3_HUMAN,tr|A0A7I2V4C2|A0A7I2V4C2_HUMAN,tr|A0A7I2YQI2|A0A7I2YQI2_HUMAN,tr|A0A7I2YQC8|A0A7I2YQC8_HUMAN,tr|A0A7I2V685|A0A7I2V685_HUMAN" 16 1678.8216 1.16 102453 15589 4 1678.82252 420.7127 Eukaryotic translation initiation factor 3 subunit I OS=Homo sapiens OX=9606 GN=EIF3I PE=1 SV=1 6.92 2685.8 - 4.73E+06 - - - 0.5546 - 3.444 0.507 - 375.4 1 2 0 0.0009 16 0 0 0 5.12E+07 4.43E+07 - - - 4.0743 1 221125_WJC_METTL3_EV_vs_WT_F07.15591.15591.3 4.80E-05 15/48 R.EDAMAMVDHC[160.03]LKK.A "sp|P43243|MATR3_HUMAN,tr|B3KM87|B3KM87_HUMAN,tr|A8MXP9|A8MXP9_HUMAN,tr|A0A0R4J2E8|A0A0R4J2E8_HUMAN,tr|H0Y8T4|H0Y8T4_HUMAN,tr|D6REM6|D6REM6_HUMAN" 6 1546.6942 1.27 102455 15591 3 1546.697051 516.572 Matrin-3 OS=Homo sapiens OX=9606 GN=MATR3 PE=1 SV=2 5.38 2686 - 863792 - - - 1.8401 - 2.601 0.538 - 311.4 1 2 0 0.0028 13 0 0 0 1.11E+08 8.72E+07 - - - 7.1291 0.8245 221125_WJC_METTL3_EV_vs_WT_F07.15592.15592.3 0.269 Aug-80 K.QTAISQPASGNTFSHHSMVSM.L "sp|Q14157|UBP2L_HUMAN,tr|F8W726|F8W726_HUMAN" 2 2216.9943 - 102456 15592 3 2216.993281 740.0054 Ubiquitin-associated protein 2-like OS=Homo sapiens OX=9606 GN=UBAP2L PE=1 SV=2 6.92 2686.1 - 699466 - - - -0.4538 - 1.876 0.249 - 72.3 1 1 0 -0.001 21 0 0 0 - - - - - 2.8242 1 221125_WJC_METTL3_EV_vs_WT_F07.15596.15596.3 1.33E-06 16/48 R.EDAMAMVDHC[160.03]LK[136.11]K[136.11].A "sp|P43243|MATR3_HUMAN,tr|B3KM87|B3KM87_HUMAN,tr|A8MXP9|A8MXP9_HUMAN,tr|A0A0R4J2E8|A0A0R4J2E8_HUMAN,tr|H0Y8T4|H0Y8T4_HUMAN,tr|D6REM6|D6REM6_HUMAN" 6 1562.7226 1.29 102458 15596 3 1562.724271 521.9148 Matrin-3 OS=Homo sapiens OX=9606 GN=MATR3 PE=1 SV=2 5.38 2686.6 - 2.00E+06 - - - 1.0661 - 3.176 0.543 - 494.2 1 2 0 0.0017 13 0 0 0 1.11E+08 8.61E+07 - - - 7.7267 1 221125_WJC_METTL3_EV_vs_WT_F07.15599.15599.3 2.17E-10 18/52 K.DIHDDQDYLHSLGK.A "sp|O75955|FLOT1_HUMAN,tr|A2AB10|A2AB10_HUMAN,tr|A0A140T910|A0A140T910_HUMAN,tr|A2AB09|A2AB09_HUMAN,tr|A2AB11|A2AB11_HUMAN,tr|A0A140T9C3|A0A140T9C3_HUMAN,tr|A0A140T9R1|A0A140T9R1_HUMAN,tr|A0A140T957|A0A140T957_HUMAN,tr|A0A140T9B1|A0A140T9B1_HUMAN,tr|A0A140T959|A0A140T959_HUMAN,tr|A2AB12|A2AB12_HUMAN,tr|A0A0G2JJQ6|A0A0G2JJQ6_HUMAN,tr|A0A140T9X0|A0A140T9X0_HUMAN,tr|A2AB13|A2AB13_HUMAN" 14 1654.7587 1.76 102461 15599 3 1654.760671 552.5935 Flotillin-1 OS=Homo sapiens OX=9606 GN=FLOT1 PE=1 SV=3 4.54 2686.9 - 1.08E+06 - - - 1.1826 - 3.281 0.643 - 444.3 1 2 0 0.002 14 0 0 0 4.93E+07 2.80E+07 - - - 8.8658 1 221125_WJC_METTL3_EV_vs_WT_F07.15600.15600.3 0.00153 21/84 K.ETPGTLSSDTNDSGVELGEESR.S "sp|O75410|TACC1_HUMAN,tr|E7EVI4|E7EVI4_HUMAN,tr|E5RJU4|E5RJU4_HUMAN,tr|E5RFM9|E5RFM9_HUMAN,tr|R4GMT7|R4GMT7_HUMAN,tr|H0YAY0|H0YAY0_HUMAN,tr|E7ET87|E7ET87_HUMAN" 7 2279.0037 1.55 102462 15600 3 2279.002397 760.6752 Transforming acidic coiled-coil-containing protein 1 OS=Homo sapiens OX=9606 GN=TACC1 PE=1 SV=2 3.77 2687 - 896342 - - - -0.5753 - 3.399 0.585 - 400.9 1 2 0 -0.0013 22 0 0 0 2.70E+07 1.74E+07 - - - 7.9625 1 221125_WJC_METTL3_EV_vs_WT_F07.15601.15601.3 9.30E-10 24/80 R.VLAGQTLDINMAGEPKPDRPK.G "sp|Q9UKM9|RALY_HUMAN,tr|Q5QPM1|Q5QPM1_HUMAN,tr|Q5QPL9|Q5QPL9_HUMAN" 3 2249.1838 3.67 102463 15601 3 2249.196938 750.7352 RNA-binding protein Raly OS=Homo sapiens OX=9606 GN=RALY PE=1 SV=1 6.09 2687.2 - 848075 - - - 5.8403 - 4.204 0.596 - 573.2 1 2 0 0.0131 21 0 0 0 4.59E+07 1.25E+07 - - - 8.624 0.9997 221125_WJC_METTL3_EV_vs_WT_F07.15603.15603.3 0.00284 16/44 K.SKLPKPVQDLIK.M sp|P09874|PARP1_HUMAN 1 1364.8391 0.94 102465 15603 3 1364.840536 455.9537 Poly [ADP-ribose] polymerase 1 OS=Homo sapiens OX=9606 GN=PARP1 PE=1 SV=4 9.7 2687.4 - 626151 - - - 1.025 - 2.749 0.396 - 197.9 1 2 1 0.0014 12 0 0 0 1.95E+08 2.06E+08 - - - 5.7576 0.992 221125_WJC_METTL3_EV_vs_WT_F07.15604.15604.3 0.0258 15/56 R.QAAVGQGDFHLLDHR.G "sp|O43819|SCO2_HUMAN,tr|A0A1W2PQK0|A0A1W2PQK0_HUMAN" 2 1662.8227 1.07 102466 15604 3 1662.82733 555.2815 "Protein SCO2 homolog, mitochondrial OS=Homo sapiens OX=9606 GN=SCO2 PE=1 SV=3" 5.98 2687.5 - 574293 - - - 2.8133 - 1.728 0.246 - 215 1 2 0 0.0047 15 0 0 0 4.13E+07 3.85E+07 - - - 2.7086 0.9999 221125_WJC_METTL3_EV_vs_WT_F07.15605.15605.4 0.000172 Dec-96 K.K[136.11]EGK[136.11]PTIVEEDDPELFK[136.11].Q sp|O75937|DNJC8_HUMAN 1 1997.0419 0.48 102467 15605 4 1997.043172 500.2678 DnaJ homolog subfamily C member 8 OS=Homo sapiens OX=9606 GN=DNAJC8 PE=1 SV=2 4.36 2687.6 - 538518 - - - 0.6179 - 2.539 0.394 - 136.3 1 2 0 0.0012 17 0 0 0 1.78E+06 3.74E+06 - - - 2.9785 1 221125_WJC_METTL3_EV_vs_WT_F07.15606.15606.2 4.93E-14 19/34 K.YVHYEIDAC[160.03]MDSEAPGSK[136.11].D "sp|Q86U44|MTA70_HUMAN,tr|H0YFV6|H0YFV6_HUMAN" 2 2078.8805 0 102468 15606 2 2079.875909 1040.4475 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 4.31 2687.8 - 355436 - - - 478.8236 - 4.02 0.775 - 734.3 1 2 0 0.9954 18 0 0 0 2.59E+06 6.89E+08 - - - 7.8731 0.9999 221125_WJC_METTL3_EV_vs_WT_F07.15607.15607.4 2.89E-05 13/84 K.THINIVVIGHVDSGK[136.11].S "sp|Q05639|EF1A2_HUMAN,sp|P68104|EF1A1_HUMAN,sp|Q5VTE0|EF1A3_HUMAN,tr|A0A2R8Y488|A0A2R8Y488_HUMAN,tr|A0A2R8YDN5|A0A2R8YDN5_HUMAN,tr|A0A7I2V659|A0A7I2V659_HUMAN,tr|A0A7I2V3H3|A0A7I2V3H3_HUMAN,tr|Q5JR01|Q5JR01_HUMAN,tr|A0A2U3TZH3|A0A2U3TZH3_HUMAN,tr|A0A7I2V5N4|A0A7I2V5N4_HUMAN,tr|A0A087WVQ9|A0A087WVQ9_HUMAN,tr|A6PW80|A6PW80_HUMAN,tr|A0A087WV01|A0A087WV01_HUMAN,tr|A0A2R8Y660|A0A2R8Y660_HUMAN,tr|A0A6Q8PFK6|A0A6Q8PFK6_HUMAN" 15 1595.8875 0.53 102469 15607 4 1595.890314 399.9791 Elongation factor 1-alpha 2 OS=Homo sapiens OX=9606 GN=EEF1A2 PE=1 SV=1 6.61 2687.9 - 344710 - - - 1.7695 - 2.428 0.475 - 134.9 1 2 0 0.0028 15 0 0 0 2.90E+06 5.49E+06 - - - 3.677 1 221125_WJC_METTL3_EV_vs_WT_F07.15608.15608.3 4.44E-11 18/92 K.AQAVTQPVPLANKPVPAQSTFPSK.T "sp|P49750|YLPM1_HUMAN,tr|H0YIQ2|H0YIQ2_HUMAN" 2 2475.3486 6.12 102470 15608 3 2475.342632 826.1235 YLP motif-containing protein 1 OS=Homo sapiens OX=9606 GN=YLPM1 PE=1 SV=4 10 2688 - 196550 - - - -2.3944 - 3.567 0.649 - 239.1 1 2 0 -0.0059 24 0 0 0 3.56E+06 5.82E+05 - - - 8.7278 0.9999 221125_WJC_METTL3_EV_vs_WT_F07.15610.15610.3 4.76E-06 18/60 K.NQVALNPQNTVFDAKR.L "sp|P0DMV8|HS71A_HUMAN,sp|P0DMV9|HS71B_HUMAN,tr|A0A0G2JIW1|A0A0G2JIW1_HUMAN" 3 1813.9435 0.14 102471 15610 3 1813.949895 605.6551 Heat shock 70 kDa protein 1A OS=Homo sapiens OX=9606 GN=HSPA1A PE=1 SV=1 8.75 2688.2 - 4.27E+06 - - - 3.5282 - 3.301 0.503 - 514.8 1 2 0 0.0064 16 0 0 0 7.88E+07 5.44E+08 - - - 7.2104 1 221125_WJC_METTL3_EV_vs_WT_F07.15612.15612.4 5.90E-05 14/78 K.DIHDDQDYLHSLGK.A "sp|O75955|FLOT1_HUMAN,tr|A2AB10|A2AB10_HUMAN,tr|A0A140T910|A0A140T910_HUMAN,tr|A2AB09|A2AB09_HUMAN,tr|A2AB11|A2AB11_HUMAN,tr|A0A140T9C3|A0A140T9C3_HUMAN,tr|A0A140T9R1|A0A140T9R1_HUMAN,tr|A0A140T957|A0A140T957_HUMAN,tr|A0A140T9B1|A0A140T9B1_HUMAN,tr|A0A140T959|A0A140T959_HUMAN,tr|A2AB12|A2AB12_HUMAN,tr|A0A0G2JJQ6|A0A0G2JJQ6_HUMAN,tr|A0A140T9X0|A0A140T9X0_HUMAN,tr|A2AB13|A2AB13_HUMAN" 14 1654.7587 1.93 102472 15612 4 1654.758404 414.697 Flotillin-1 OS=Homo sapiens OX=9606 GN=FLOT1 PE=1 SV=3 4.54 2688.5 - 1.80E+06 - - - -0.1873 - 2.528 0.502 - 198.6 1 2 0 -0.0003 14 0 0 0 2.90E+07 1.50E+07 - - - 3.9329 1 221125_WJC_METTL3_EV_vs_WT_F07.15614.15614.3 6.54E-09 18/52 K.DIHDDQDYLHSLGK[136.11].A "sp|O75955|FLOT1_HUMAN,tr|A2AB10|A2AB10_HUMAN,tr|A0A140T910|A0A140T910_HUMAN,tr|A2AB09|A2AB09_HUMAN,tr|A2AB11|A2AB11_HUMAN,tr|A0A140T9C3|A0A140T9C3_HUMAN,tr|A0A140T9R1|A0A140T9R1_HUMAN,tr|A0A140T957|A0A140T957_HUMAN,tr|A0A140T9B1|A0A140T9B1_HUMAN,tr|A0A140T959|A0A140T959_HUMAN,tr|A2AB12|A2AB12_HUMAN,tr|A0A0G2JJQ6|A0A0G2JJQ6_HUMAN,tr|A0A140T9X0|A0A140T9X0_HUMAN,tr|A2AB13|A2AB13_HUMAN" 14 1662.7729 1.76 102474 15614 3 1662.773183 555.2649 Flotillin-1 OS=Homo sapiens OX=9606 GN=FLOT1 PE=1 SV=3 4.54 2688.7 - 1.97E+06 - - - 0.1618 - 3.362 0.677 - 490.2 1 2 0 0.0003 14 0 0 0 4.93E+07 2.80E+07 - - - 9.3102 1 221125_WJC_METTL3_EV_vs_WT_F07.15616.15616.3 1.38E-08 20/60 R.SQTEAVTFLANHDDSR[166.11].A "sp|Q9Y2S7|PDIP2_HUMAN,tr|B4DEM9|B4DEM9_HUMAN" 2 1799.8314 1.22 102476 15616 3 1799.834625 600.9511 Polymerase delta-interacting protein 2 OS=Homo sapiens OX=9606 GN=POLDIP2 PE=1 SV=1 4.53 2688.9 - 921708 - - - 1.8057 - 3.841 0.629 - 565.9 1 2 0 0.0032 16 0 0 0 2.35E+07 1.94E+07 - - - 9.0048 0.9975 221125_WJC_METTL3_EV_vs_WT_F07.15618.15618.4 5.23E-11 19/90 T.ANQIPIISAEHLTSHK.Y "sp|Q9NR56|MBNL1_HUMAN,tr|Q86VM6|Q86VM6_HUMAN,tr|A0A0A0MQX8|A0A0A0MQX8_HUMAN" 3 1757.9424 1.62 102478 15618 4 1757.940781 440.4929 Muscleblind-like protein 1 OS=Homo sapiens OX=9606 GN=MBNL1 PE=1 SV=2 6.96 2689.1 - 732845 - - - -0.9397 - 3.528 0.544 - 272 1 1 0 -0.0017 16 0 0 0 4.37E+07 2.70E+07 - - - 4.4046 1 221125_WJC_METTL3_EV_vs_WT_F07.15619.15619.3 5.05E-07 20/60 R.SQTEAVTFLANHDDSR.A "sp|Q9Y2S7|PDIP2_HUMAN,tr|B4DEM9|B4DEM9_HUMAN" 2 1789.8231 1.21 102479 15619 3 1789.824524 597.615 Polymerase delta-interacting protein 2 OS=Homo sapiens OX=9606 GN=POLDIP2 PE=1 SV=1 4.53 2689.3 - 658994 - - - 0.7928 - 2.977 0.584 - 530.1 1 2 0 0.0014 16 0 0 0 2.35E+07 1.94E+07 - - - 7.8498 1 221125_WJC_METTL3_EV_vs_WT_F07.15620.15620.2 2.54E-08 18/42 K.ETPGTLSSDTNDSGVELGEESR.S "sp|O75410|TACC1_HUMAN,tr|E7EVI4|E7EVI4_HUMAN,tr|E5RJU4|E5RJU4_HUMAN,tr|E5RFM9|E5RFM9_HUMAN,tr|R4GMT7|R4GMT7_HUMAN,tr|H0YAY0|H0YAY0_HUMAN,tr|E7ET87|E7ET87_HUMAN" 7 2279.0037 1.61 102480 15620 2 2279.007769 1140.5091 Transforming acidic coiled-coil-containing protein 1 OS=Homo sapiens OX=9606 GN=TACC1 PE=1 SV=2 3.77 2689.4 - 633548 - - - 1.7819 - 3.564 0.734 - 881.9 1 2 0 0.0041 22 0 0 0 9.09E+06 5.67E+06 - - - 7.5856 0.9997 221125_WJC_METTL3_EV_vs_WT_F07.15621.15621.3 0.000723 15/64 K.VAAQNLIQNTNIDNGQK[136.11].S "sp|Q9NX70|MED29_HUMAN,tr|M0R3F3|M0R3F3_HUMAN,tr|B4DUA7|B4DUA7_HUMAN" 3 1847.9581 0.46 102481 15621 3 1847.953768 616.9933 Mediator of RNA polymerase II transcription subunit 29 OS=Homo sapiens OX=9606 GN=MED29 PE=1 SV=1 5.81 2689.5 - 526945 - - - -2.3383 - 2.826 0.348 - 332.5 1 2 0 -0.0043 17 0 0 0 2.02E+06 4.41E+06 - - - 5.0431 0.9951 221125_WJC_METTL3_EV_vs_WT_F07.15623.15623.3 0.0884 Sep-60 K.EEYQQTWYHEGPNSLK.V sp|O43172|PRP4_HUMAN 1 2007.8963 3.03 102483 15623 3 2007.896478 670.306 U4\U6 small nuclear ribonucleoprotein Prp4 OS=Homo sapiens OX=9606 GN=PRPF4 PE=1 SV=2 4.75 2689.8 - 341571 - - - 0.1036 - 1.706 0.21 - 70.5 1 2 0 0.0002 16 0 0 0 2.66E+06 8.78E+05 - - - 2.2518 0.9998 221125_WJC_METTL3_EV_vs_WT_F07.15624.15624.2 0.00012 28-Nov R.TNVPTFSQSNLEQQK.Q sp|Q96BU1|S1PBP_HUMAN 1 1719.8428 1.74 102484 15624 2 1719.844851 860.9287 S100P-binding protein OS=Homo sapiens OX=9606 GN=S100PBP PE=1 SV=1 5.66 2689.9 - 327718 - - - 1.2053 - 2.407 0.513 - 226.9 1 2 0 0.0021 15 0 0 0 3.28E+06 1.89E+06 - - - 4.9889 1 221125_WJC_METTL3_EV_vs_WT_F07.15625.15625.2 4.25E-11 13/24 R.EDAMAMVDHC[160.03]LKK.A "sp|P43243|MATR3_HUMAN,tr|B3KM87|B3KM87_HUMAN,tr|A8MXP9|A8MXP9_HUMAN,tr|A0A0R4J2E8|A0A0R4J2E8_HUMAN,tr|H0Y8T4|H0Y8T4_HUMAN,tr|D6REM6|D6REM6_HUMAN" 6 1546.6942 0.91 102485 15625 2 1547.695016 774.3544 Matrin-3 OS=Homo sapiens OX=9606 GN=MATR3 PE=1 SV=2 5.38 2690 - 219381 - - - 647.0646 - 2.711 0.663 - 636.5 1 2 0 1.0008 13 0 0 0 3.29E+06 3.61E+06 - - - 6.1833 1 221125_WJC_METTL3_EV_vs_WT_F07.15629.15629.4 1.26E-07 23/120 R.VLAGQTLDINMAGEPKPDRPK.G "sp|Q9UKM9|RALY_HUMAN,tr|Q5QPM1|Q5QPM1_HUMAN,tr|Q5QPL9|Q5QPL9_HUMAN" 3 2249.1838 1.26 102487 15629 4 2249.183144 563.3032 RNA-binding protein Raly OS=Homo sapiens OX=9606 GN=RALY PE=1 SV=1 6.09 2690.6 - 8.35E+06 - - - -0.2926 - 3.566 0.56 - 449.2 1 2 0 -0.0007 21 0 0 0 1.28E+08 1.02E+08 - - - 4.5204 1 221125_WJC_METTL3_EV_vs_WT_F07.15630.15630.4 1.54E-08 15/72 R.EDAMAMVDHC[160.03]LK[136.11]K[136.11].A "sp|P43243|MATR3_HUMAN,tr|B3KM87|B3KM87_HUMAN,tr|A8MXP9|A8MXP9_HUMAN,tr|A0A0R4J2E8|A0A0R4J2E8_HUMAN,tr|H0Y8T4|H0Y8T4_HUMAN,tr|D6REM6|D6REM6_HUMAN" 6 1562.7226 1.25 102488 15630 4 1562.719282 391.6879 Matrin-3 OS=Homo sapiens OX=9606 GN=MATR3 PE=1 SV=2 5.38 2690.6 - 6.97E+06 - - - -2.1264 - 2.969 0.603 - 271.6 1 2 0 -0.0033 13 0 0 0 9.47E+07 7.59E+07 - - - 4.8771 1 221125_WJC_METTL3_EV_vs_WT_F07.15633.15633.4 1.89E-07 15/78 K.DIHDDQDYLHSLGK[136.11].A "sp|O75955|FLOT1_HUMAN,tr|A2AB10|A2AB10_HUMAN,tr|A0A140T910|A0A140T910_HUMAN,tr|A2AB09|A2AB09_HUMAN,tr|A2AB11|A2AB11_HUMAN,tr|A0A140T9C3|A0A140T9C3_HUMAN,tr|A0A140T9R1|A0A140T9R1_HUMAN,tr|A0A140T957|A0A140T957_HUMAN,tr|A0A140T9B1|A0A140T9B1_HUMAN,tr|A0A140T959|A0A140T959_HUMAN,tr|A2AB12|A2AB12_HUMAN,tr|A0A0G2JJQ6|A0A0G2JJQ6_HUMAN,tr|A0A140T9X0|A0A140T9X0_HUMAN,tr|A2AB13|A2AB13_HUMAN" 14 1662.7729 1.93 102491 15633 4 1662.768142 416.7005 Flotillin-1 OS=Homo sapiens OX=9606 GN=FLOT1 PE=1 SV=3 4.54 2690.8 - 2.40E+06 - - - -2.8699 - 2.792 0.627 - 221.4 1 2 0 -0.0048 14 0 0 0 2.90E+07 1.50E+07 - - - 5.0558 1 221125_WJC_METTL3_EV_vs_WT_F07.15635.15635.3 1.18E-11 22/80 K.NIDDGTSDRPYSHALVAGIDR.Y "sp|P61353|RL27_HUMAN,tr|K7ELC7|K7ELC7_HUMAN" 2 2271.088 1.26 102493 15635 3 2271.093379 758.0366 60S ribosomal protein L27 OS=Homo sapiens OX=9606 GN=RPL27 PE=1 SV=2 4.56 2691 - 1.51E+06 - - - 2.3742 - 3.605 0.675 - 383.6 1 2 0 0.0054 21 0 0 0 6.10E+07 4.83E+07 - - - 9.1384 0.9669 221125_WJC_METTL3_EV_vs_WT_F07.15638.15638.3 0.00106 Oct-72 K.GYK[136.11]PPDEGPSEYQTIPLNK[136.11].L "sp|Q92905|CSN5_HUMAN,tr|E5RHH5|E5RHH5_HUMAN,tr|E5RHF2|E5RHF2_HUMAN" 3 2148.071 4.36 102496 15638 3 2148.058002 717.0309 COP9 signalosome complex subunit 5 OS=Homo sapiens OX=9606 GN=COPS5 PE=1 SV=4 4.68 2691.3 - 755464 - - - -6.051 - 1.942 0.281 - 65.3 1 2 0 -0.013 19 0 0 0 1.81E+07 4.16E+06 - - - 3.2999 1 221125_WJC_METTL3_EV_vs_WT_F07.15639.15639.3 4.37E-14 23/60 K.R[166.11]SELEEQQMHLNVGLR[166.11].K "sp|Q14204|DYHC1_HUMAN,tr|A0A7P0T8N2|A0A7P0T8N2_HUMAN,tr|A0A7P0T9C4|A0A7P0T9C4_HUMAN,tr|A0A7P0TBJ7|A0A7P0TBJ7_HUMAN,tr|A0A7P0T9K2|A0A7P0T9K2_HUMAN,tr|A0A2R8Y706|A0A2R8Y706_HUMAN,tr|A0A7P0T916|A0A7P0T916_HUMAN,tr|A0A7P0TB75|A0A7P0TB75_HUMAN,tr|A0A7P0T8W5|A0A7P0T8W5_HUMAN,tr|A0A7P0TAF3|A0A7P0TAF3_HUMAN,tr|A0A7P0T9F1|A0A7P0T9F1_HUMAN,tr|A0A7P0TAW9|A0A7P0TAW9_HUMAN,tr|A0A7P0TA13|A0A7P0TA13_HUMAN,tr|A0A7P0T7V5|A0A7P0T7V5_HUMAN,tr|A0A7P0T9R4|A0A7P0T9R4_HUMAN,tr|A0A2R8Y5T0|A0A2R8Y5T0_HUMAN,tr|A0A2R8YFZ7|A0A2R8YFZ7_HUMAN,tr|A0A7P0T825|A0A7P0T825_HUMAN,tr|A0A2R8Y6H2|A0A2R8Y6H2_HUMAN,tr|A0A7P0TAM4|A0A7P0TAM4_HUMAN" 20 1957.9907 1.46 102497 15639 3 1957.992483 653.6708 Cytoplasmic dynein 1 heavy chain 1 OS=Homo sapiens OX=9606 GN=DYNC1H1 PE=1 SV=5 5.5 2691.4 - 747875 - - - 0.9193 - 3.937 0.65 - 874.5 1 2 0 0.0018 16 0 0 0 5.95E+06 4.06E+06 - - - 9.3027 0.9802 221125_WJC_METTL3_EV_vs_WT_F07.15640.15640.4 2.80E-05 17/90 T.ANQIPIISAEHLTSHK[136.11].Y "sp|Q9NR56|MBNL1_HUMAN,tr|Q86VM6|Q86VM6_HUMAN,tr|A0A0A0MQX8|A0A0A0MQX8_HUMAN" 3 1765.9566 1.62 102498 15640 4 1765.950914 442.4964 Muscleblind-like protein 1 OS=Homo sapiens OX=9606 GN=MBNL1 PE=1 SV=2 6.96 2691.6 - 563649 - - - -3.2385 - 3.244 0.466 - 274.3 1 1 0 -0.0057 16 0 0 0 4.05E+07 2.51E+07 - - - 3.695 1 221125_WJC_METTL3_EV_vs_WT_F07.15646.15646.4 2.88E-08 Dec-72 R.EDAMAMVDHC[160.03]LKK.A "sp|P43243|MATR3_HUMAN,tr|B3KM87|B3KM87_HUMAN,tr|A8MXP9|A8MXP9_HUMAN,tr|A0A0R4J2E8|A0A0R4J2E8_HUMAN,tr|H0Y8T4|H0Y8T4_HUMAN,tr|D6REM6|D6REM6_HUMAN" 6 1546.6942 1.25 102502 15646 4 1546.690152 387.6808 Matrin-3 OS=Homo sapiens OX=9606 GN=MATR3 PE=1 SV=2 5.38 2692.3 - 7.54E+06 - - - -2.6204 - 2.411 0.569 - 116.9 1 2 0 -0.0041 13 0 0 0 9.47E+07 7.58E+07 - - - 4.5037 1 221125_WJC_METTL3_EV_vs_WT_F07.15649.15649.3 7.36E-10 20/64 R.HQLEEC[160.03]LAGNNQLSLEK.N "sp|Q15643|TRIPB_HUMAN,tr|H0YJ97|H0YJ97_HUMAN" 2 1981.9527 1.44 102505 15649 3 1981.955134 661.6582 Thyroid receptor-interacting protein 11 OS=Homo sapiens OX=9606 GN=TRIP11 PE=1 SV=3 4.75 2692.6 - 2.19E+06 - - - 1.2079 - 3.838 0.702 - 626.5 1 2 0 0.0024 17 0 0 0 6.94E+07 4.83E+07 - - - 9.7637 0.9996 221125_WJC_METTL3_EV_vs_WT_F07.15650.15650.3 8.38E-07 14/44 K.SK[136.11]LPK[136.11]PVQDLIK[136.11].M sp|P09874|PARP1_HUMAN 1 1388.8817 0.95 102506 15650 3 1388.877297 463.9679 Poly [ADP-ribose] polymerase 1 OS=Homo sapiens OX=9606 GN=PARP1 PE=1 SV=4 9.7 2692.7 - 1.67E+06 - - - -3.1968 - 2.675 0.527 - 160.8 1 2 1 -0.0044 12 0 0 0 1.98E+08 2.10E+08 - - - 7.1417 1 221125_WJC_METTL3_EV_vs_WT_F07.15654.15654.3 7.67E-12 23/64 R.HQLEEC[160.03]LAGNNQLSLEK[136.11].N "sp|Q15643|TRIPB_HUMAN,tr|H0YJ97|H0YJ97_HUMAN" 2 1989.9669 1.44 102508 15654 3 1989.958978 664.3296 Thyroid receptor-interacting protein 11 OS=Homo sapiens OX=9606 GN=TRIP11 PE=1 SV=3 4.75 2693.2 - 2.64E+06 - - - -4.0011 - 4.056 0.657 - 1074 1 2 0 -0.008 17 0 0 0 6.94E+07 4.83E+07 - - - 9.4 1 221125_WJC_METTL3_EV_vs_WT_F07.15655.15655.3 1.04E-06 13/48 R.KDHPFGFVAVPTK.N "sp|P63279|UBC9_HUMAN,tr|B0QYN7|B0QYN7_HUMAN,tr|H3BPC4|H3BPC4_HUMAN,tr|H3BQQ9|H3BQQ9_HUMAN" 4 1441.7718 0.94 102509 15655 3 1441.770437 481.5979 SUMO-conjugating enzyme UBC9 OS=Homo sapiens OX=9606 GN=UBE2I PE=1 SV=1 8.6 2693.3 - 510415 - - - -0.935 - 2.472 0.458 - 204.7 1 2 0 -0.0013 13 0 0 0 6.33E+06 6.71E+06 - - - 6.0997 0.9994 221125_WJC_METTL3_EV_vs_WT_F07.15657.15657.2 3.75E-06 Dec-38 K.SSSGGGGGLLLHASEPESSS.- "sp|P78426|NKX61_HUMAN,tr|F8VWZ9|F8VWZ9_HUMAN" 2 1814.8283 - 102511 15657 2 1814.822072 908.4214 Homeobox protein Nkx-6.1 OS=Homo sapiens OX=9606 GN=NKX6-1 PE=1 SV=2 4.51 2693.6 - 680660 - - - -3.4042 - 2.621 0.525 - 217.3 1 2 0 -0.0062 20 0 0 0 - - - - - 5.2857 1 221125_WJC_METTL3_EV_vs_WT_F07.15658.15658.2 6.73E-13 19/34 K.YVHYEIDAC[160.03]MDSEAPGSK.D "sp|Q86U44|MTA70_HUMAN,tr|H0YFV6|H0YFV6_HUMAN" 2 2070.8663 -1 102512 15658 2 2071.860827 1036.4404 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 4.31 2693.7 - 594827 - - - 480.2507 - 3.803 0.738 - 710 1 2 0 0.9945 18 0 0 0 0.00E+00 0.00E+00 - - - 7.4637 0.9966 221125_WJC_METTL3_EV_vs_WT_F07.15661.15661.3 0.000419 Nov-36 R.IKFEMEQNLR.Q "sp|P35527|K1C9_HUMAN,tr|K7EQQ3|K7EQQ3_HUMAN" 2 1306.6704 999 102513 15661 3 1306.666442 436.5641 "Keratin, type I cytoskeletal 9 OS=Homo sapiens OX=9606 GN=KRT9 PE=1 SV=3" 6.14 2694.1 - 2.98E+06 - - - -2.9962 - 2.142 0.341 - 197.7 1 2 1 -0.0039 10 0 0 0 4.50E+07 0.00E+00 - - - 4.5653 0.9898 221125_WJC_METTL3_EV_vs_WT_F07.15662.15662.3 2.14E-07 16/60 K.LTEDKETLQYLQQNAK.E "sp|Q9BSJ2|GCP2_HUMAN,tr|A0A804HLH6|A0A804HLH6_HUMAN,tr|A0A804HJH7|A0A804HJH7_HUMAN,tr|F2Z2B9|F2Z2B9_HUMAN,tr|A0A804HK74|A0A804HK74_HUMAN,tr|A0A804HL95|A0A804HL95_HUMAN,tr|A0A804HJ08|A0A804HJ08_HUMAN,tr|A0A804HJQ4|A0A804HJQ4_HUMAN,tr|A0A804HJS9|A0A804HJS9_HUMAN,tr|A0A804HI27|A0A804HI27_HUMAN" 10 1920.9793 2.73 102514 15662 3 1920.965514 641.3337 Gamma-tubulin complex component 2 OS=Homo sapiens OX=9606 GN=TUBGCP2 PE=1 SV=2 4.68 2694.2 - 1.42E+06 - - - -7.162 - 2.738 0.476 - 288.3 1 2 1 -0.0138 16 0 0 0 9.01E+07 3.30E+07 - - - 6.4275 1 221125_WJC_METTL3_EV_vs_WT_F07.15663.15663.3 3.64E-14 19/72 K.LHISPSNMTNQNTNEYLEK.L sp|Q13547|HDAC1_HUMAN 1 2232.0481 2.33 102515 15663 3 2232.04044 745.0233 Histone deacetylase 1 OS=Homo sapiens OX=9606 GN=HDAC1 PE=1 SV=1 5.4 2694.3 - 2.43E+06 - - - -3.43 - 3.815 0.681 - 433.5 1 2 0 -0.0077 19 0 0 0 7.15E+08 3.07E+08 - - - 9.4199 0.9998 221125_WJC_METTL3_EV_vs_WT_F07.15665.15665.4 9.88E-08 21/120 K.EVVVYLDDNQKPPVGEGLNRK.A "sp|P52948|NUP98_HUMAN,tr|A0A3B3ITD8|A0A3B3ITD8_HUMAN" 2 2368.2387 3.08 102517 15665 4 2368.22959 593.0669 Nuclear pore complex protein Nup98-Nup96 OS=Homo sapiens OX=9606 GN=NUP98 PE=1 SV=4 4.78 2694.6 - 1.22E+06 - - - -3.8358 - 2.896 0.525 - 197 1 2 0 -0.0091 21 0 0 0 6.61E+07 2.15E+07 - - - 4.1447 0.9992 221125_WJC_METTL3_EV_vs_WT_F07.15669.15669.4 3.26E-08 19/102 K.YVHYEIDAC[160.03]MDSEAPGSK[136.11].D "sp|Q86U44|MTA70_HUMAN,tr|H0YFV6|H0YFV6_HUMAN" 2 2078.8805 0.01 102519 15669 4 2079.879295 520.7274 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 4.31 2695 - 2.36E+06 - - - 480.4523 - 3.475 0.621 - 288.1 1 2 0 0.9988 18 0 0 0 3.69E+05 4.69E+07 - - - 4.7812 0.9999 221125_WJC_METTL3_EV_vs_WT_F07.15674.15674.3 1.12E-06 19/44 K.VKELEEELQHLK.Q "sp|P82094|TMF1_HUMAN,tr|F8WF45|F8WF45_HUMAN,tr|A0A2R8Y7M0|A0A2R8Y7M0_HUMAN" 3 1493.809 1.4 102522 15674 3 1493.806327 498.9436 TATA element modulatory factor OS=Homo sapiens OX=9606 GN=TMF1 PE=1 SV=2 4.91 2695.7 - 1.46E+06 - - - -1.7619 - 3.453 0.532 - 382.9 1 2 1 -0.0026 12 0 0 0 1.77E+08 1.26E+08 - - - 7.9055 1 221125_WJC_METTL3_EV_vs_WT_F07.15683.15683.4 1.98E-07 14/120 K.NIDDGTSDRPYSHALVAGIDR.Y "sp|P61353|RL27_HUMAN,tr|K7ELC7|K7ELC7_HUMAN" 2 2271.088 1.16 102527 15683 4 2271.083133 568.7793 60S ribosomal protein L27 OS=Homo sapiens OX=9606 GN=RPL27 PE=1 SV=2 4.56 2696.8 - 6.04E+06 - - - -2.1373 - 2.194 0.583 - 97.5 1 2 0 -0.0049 21 0 0 0 2.06E+08 1.77E+08 - - - 4.5589 0.9998 221125_WJC_METTL3_EV_vs_WT_F07.15695.15695.3 1.79E-07 22/44 K.VK[136.11]ELEEELQHLK[136.11].Q "sp|P82094|TMF1_HUMAN,tr|F8WF45|F8WF45_HUMAN,tr|A0A2R8Y7M0|A0A2R8Y7M0_HUMAN" 3 1509.8374 1.4 102533 15695 3 1509.8333 504.2864 TATA element modulatory factor OS=Homo sapiens OX=9606 GN=TMF1 PE=1 SV=2 4.91 2698.1 - 2.36E+06 - - - -2.6884 - 3.391 0.548 - 417.1 1 2 1 -0.0041 12 0 0 0 1.76E+08 1.26E+08 - - - 8.0333 1 221125_WJC_METTL3_EV_vs_WT_F07.15751.15751.3 2.09E-16 23/72 K.NSASVQNSSVAVLSVNHIK.R "sp|O75179|ANR17_HUMAN,tr|H0YM23|H0YM23_HUMAN" 2 1953.028 3.29 102549 15751 3 1953.028455 652.0166 Ankyrin repeat domain-containing protein 17 OS=Homo sapiens OX=9606 GN=ANKRD17 PE=1 SV=3 8.76 2706.2 - 2.61E+06 - - - 0.257 - 4.129 0.695 - 676.5 1 2 0 0.0005 19 0 0 0 8.94E+07 2.72E+07 - - - 9.7723 1 221125_WJC_METTL3_EV_vs_WT_F07.15752.15752.3 3.87E-14 21/72 K.NSASVQNSSVAVLSVNHIK[136.11].R "sp|O75179|ANR17_HUMAN,tr|H0YM23|H0YM23_HUMAN" 2 1961.0422 3.31 102550 15752 3 1961.03792 654.688 Ankyrin repeat domain-containing protein 17 OS=Homo sapiens OX=9606 GN=ANKRD17 PE=1 SV=3 8.76 2706.3 - 1.05E+06 - - - -2.1585 - 4.113 0.671 - 595.1 1 2 0 -0.0042 19 0 0 0 8.86E+07 2.68E+07 - - - 9.4941 0.9999 221125_WJC_METTL3_EV_vs_WT_F07.15754.15754.3 1.42E-06 15/56 R.ADTQTYQPYNKDWIK.E sp|P84090|ERH_HUMAN 1 1869.8897 2.35 102552 15754 3 1869.889622 624.3039 Enhancer of rudimentary homolog OS=Homo sapiens OX=9606 GN=ERH PE=1 SV=1 6 2706.4 - 2.98E+06 - - - -0.0567 - 2.862 0.524 - 289.3 1 2 1 -0.0001 15 0 0 0 2.10E+09 8.93E+08 - - - 7.1259 1 221125_WJC_METTL3_EV_vs_WT_F07.15755.15755.4 2.40E-12 25/102 R.HGLLVPNNTTDQELQHIR.N "sp|P56537|IF6_HUMAN,tr|B7ZBH1|B7ZBH1_HUMAN" 2 2084.0763 3.07 102553 15755 4 2084.074929 522.0264 Eukaryotic translation initiation factor 6 OS=Homo sapiens OX=9606 GN=EIF6 PE=1 SV=1 5.99 2706.6 - 2.44E+06 - - - -0.6578 - 4.066 0.623 - 633.5 1 2 0 -0.0014 18 0 0 0 1.22E+08 3.95E+07 - - - 5.1287 0.9896 221125_WJC_METTL3_EV_vs_WT_F07.15761.15761.3 3.69E-09 16/60 Q.THISDTSVVLSMDNNR.N "sp|P48668|K2C6C_HUMAN,sp|P04259|K2C6B_HUMAN,sp|P02538|K2C6A_HUMAN" 3 1787.8472 17.33 102557 15761 3 1787.842117 596.9563 "Keratin, type II cytoskeletal 6C OS=Homo sapiens OX=9606 GN=KRT6C PE=1 SV=3" 5.18 2707.3 - 1.27E+06 - - - -2.8498 - 2.867 0.473 - 291.4 1 1 0 -0.0051 16 0 0 0 3.27E+07 1.89E+06 - - - 6.5146 1 221125_WJC_METTL3_EV_vs_WT_F07.15774.15774.3 4.10E-06 17/60 K.FSVC[160.03]VLGDQQHC[160.03]DEAK[136.11].A sp|P62906|RL10A_HUMAN 1 1899.8335 0.92 102565 15774 3 1899.831381 634.2851 60S ribosomal protein L10a OS=Homo sapiens OX=9606 GN=RPL10A PE=1 SV=2 4.54 2708.9 - 1.67E+06 - - - -1.1064 - 2.693 0.562 - 230.4 1 2 0 -0.0021 16 0 0 0 3.05E+08 3.31E+08 - - - 7.3471 0.9981 221125_WJC_METTL3_EV_vs_WT_F07.15775.15775.4 3.05E-07 19/114 F.SSMAEVDAAMAARPHSIDGR.V "sp|P22626|ROA2_HUMAN,tr|A0A7I2YQN4|A0A7I2YQN4_HUMAN,tr|A0A7I2V4N0|A0A7I2V4N0_HUMAN,tr|A0A024RA28|A0A024RA28_HUMAN,tr|A0A7I2V4N1|A0A7I2V4N1_HUMAN,tr|A0A7I2V4I6|A0A7I2V4I6_HUMAN,tr|A0A087WUI2|A0A087WUI2_HUMAN,tr|A0A7I2V4S4|A0A7I2V4S4_HUMAN,tr|A0A7I2V323|A0A7I2V323_HUMAN,tr|A0A7I2V3P1|A0A7I2V3P1_HUMAN,tr|A0A7I2V3P7|A0A7I2V3P7_HUMAN" 11 2070.9575 1.99 102566 15775 4 2070.95656 518.7467 Heterogeneous nuclear ribonucleoproteins A2\B1 OS=Homo sapiens OX=9606 GN=HNRNPA2B1 PE=1 SV=2 5.36 2709 - 1.95E+06 - - - -0.4573 - 2.893 0.587 - 224.4 1 1 0 -0.0009 20 0 0 0 2.71E+07 1.36E+07 - - - 4.6901 0.9501 221125_WJC_METTL3_EV_vs_WT_F07.15777.15777.2 0.00882 16-Sep Q.VINDGDK[136.11]PK[136.11].V "sp|P0DMV8|HS71A_HUMAN,sp|P0DMV9|HS71B_HUMAN,tr|A0A0G2JIW1|A0A0G2JIW1_HUMAN" 3 1000.5524 0.11 102568 15777 2 1000.554258 501.2835 Heat shock 70 kDa protein 1A OS=Homo sapiens OX=9606 GN=HSPA1A PE=1 SV=1 5.93 2709.3 - 1.03E+06 - - - 1.847 - 1.68 0.362 - 225.8 1 1 0 0.0018 9 0 0 0 3.20E+06 2.85E+07 - - - 3.215 0.9998 221125_WJC_METTL3_EV_vs_WT_F07.15783.15783.4 0.000478 15/90 R.ETNLDSLPLVDTHSK[136.11]R[166.11].T sp|P08670|VIME_HUMAN 1 1841.9602 1.62 102572 15783 4 1841.958835 461.4973 Vimentin OS=Homo sapiens OX=9606 GN=VIM PE=1 SV=4 5.38 2710 - 1.15E+06 - - - -0.747 - 2.559 0.373 - 145.6 1 2 0 -0.0014 16 0 0 0 1.04E+08 6.41E+07 - - - 2.8032 1 221125_WJC_METTL3_EV_vs_WT_F07.15784.15784.2 6.66E-10 16/32 R.ISIGGGSC[160.03]AISGGYGSR.A "sp|P48668|K2C6C_HUMAN,sp|P04259|K2C6B_HUMAN,sp|P02538|K2C6A_HUMAN" 3 1597.7519 999 102573 15784 2 1597.749007 799.8832 "Keratin, type II cytoskeletal 6C OS=Homo sapiens OX=9606 GN=KRT6C PE=1 SV=3" 8.22 2710.1 - 913983 - - - -1.7825 - 2.935 0.678 - 553.5 1 2 0 -0.0028 17 0 0 0 2.61E+07 0.00E+00 - - - 6.6949 1 221125_WJC_METTL3_EV_vs_WT_F07.15785.15785.4 1.74E-08 21/126 R.QMMVASGNQLVEC[160.03]QEC[160.03]HNLYHR.D "sp|Q96CB8|INT12_HUMAN,tr|A0A087WXN4|A0A087WXN4_HUMAN" 2 2703.1774 0.67 102574 15785 4 2703.171573 676.8016 Integrator complex subunit 12 OS=Homo sapiens OX=9606 GN=INTS12 PE=1 SV=1 6 2710.2 - 685265 - - - -2.1667 - 3.817 0.646 - 311.8 1 2 0 -0.0059 22 0 0 0 9.09E+06 1.35E+07 - - - 5.2854 1 221125_WJC_METTL3_EV_vs_WT_F07.15787.15787.2 3.01E-07 14/28 R.ADTQTYQPYNK[136.11]DWIK[136.11].E sp|P84090|ERH_HUMAN 1 1885.9181 2.3 102576 15787 2 1885.917839 943.9663 Enhancer of rudimentary homolog OS=Homo sapiens OX=9606 GN=ERH PE=1 SV=1 6 2710.5 - 489992 - - - -0.1532 - 2.725 0.62 - 497.8 1 2 1 -0.0003 15 0 0 0 8.12E+07 3.53E+07 - - - 6.0848 0.9986 221125_WJC_METTL3_EV_vs_WT_F07.15791.15791.3 4.06E-08 15/64 M.QTHISDTSVVLSMDNNR.N "sp|P48668|K2C6C_HUMAN,sp|P04259|K2C6B_HUMAN,sp|P02538|K2C6A_HUMAN" 3 1915.9058 341.52 102578 15791 3 1915.905006 639.6425 "Keratin, type II cytoskeletal 6C OS=Homo sapiens OX=9606 GN=KRT6C PE=1 SV=3" 5.21 2710.9 - 2.22E+06 - - - -0.4087 - 2.99 0.573 - 311.9 1 1 0 -0.0008 17 0 0 0 1.73E+08 5.05E+05 - - - 7.6952 1 221125_WJC_METTL3_EV_vs_WT_F07.15793.15793.2 6.03E-07 15/28 R.ADTQTYQPYNKDWIK.E sp|P84090|ERH_HUMAN 1 1869.8897 2.3 102580 15793 2 1869.8881 935.9521 Enhancer of rudimentary homolog OS=Homo sapiens OX=9606 GN=ERH PE=1 SV=1 6 2711.1 - 1.61E+06 - - - -0.8706 - 3.115 0.591 - 606.8 1 2 1 -0.0016 15 0 0 0 8.12E+07 3.53E+07 - - - 6.1991 1 221125_WJC_METTL3_EV_vs_WT_F07.15795.15795.3 2.25E-05 16/60 R.ETNLDSLPLVDTHSKR.T sp|P08670|VIME_HUMAN 1 1823.9377 1.17 102582 15795 3 1823.935865 608.9865 Vimentin OS=Homo sapiens OX=9606 GN=VIM PE=1 SV=4 5.38 2711.4 - 838024 - - - -1.0285 - 2.879 0.44 - 334.6 1 2 0 -0.0019 16 0 0 0 6.25E+07 5.35E+07 - - - 6.1583 0.9972 221125_WJC_METTL3_EV_vs_WT_F07.15796.15796.3 0.000324 14/64 R.AADEEAFEDNSEEYIR[166.11]R[166.11].D sp|P55060|XPO2_HUMAN 1 2062.8983 1.39 102583 15796 3 2062.890414 688.64 Exportin-2 OS=Homo sapiens OX=9606 GN=CSE1L PE=1 SV=3 4 2711.5 - 719451 - - - -3.8141 - 2.541 0.277 - 252.6 1 2 0 -0.0079 17 0 0 0 2.44E+07 1.76E+07 - - - 3.982 0.9992 221125_WJC_METTL3_EV_vs_WT_F07.15797.15797.4 3.02E-05 15/84 K.TFKPAIQELKPPTYK.L "sp|P82650|RT22_HUMAN,tr|G5E9W7|G5E9W7_HUMAN,tr|A0A7P0MKV3|A0A7P0MKV3_HUMAN,tr|H7C5F2|H7C5F2_HUMAN,tr|H7C5H3|H7C5H3_HUMAN" 5 1759.9873 0.99 102584 15797 4 1759.987662 441.0041 "28S ribosomal protein S22, mitochondrial OS=Homo sapiens OX=9606 GN=MRPS22 PE=1 SV=1" 9.52 2711.6 - 609514 - - - 0.2295 - 2.502 0.299 - 118.8 1 2 0 0.0004 15 0 0 0 2.45E+07 2.48E+07 - - - 2.1565 1 221125_WJC_METTL3_EV_vs_WT_F07.15803.15803.3 3.49E-11 19/84 K.DHTPSQELALTQSVGGDSSADR[166.11].L "sp|Q86U44|MTA70_HUMAN,tr|H0YFV6|H0YFV6_HUMAN" 2 2280.0494 0.02 102587 15803 3 2280.050662 761.0237 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 4.22 2712.4 - 966871 - - - 0.568 - 3.859 0.623 - 350.1 1 2 0 0.0013 22 0 0 0 8.83E+06 4.14E+08 - - - 8.6871 0.9321 221125_WJC_METTL3_EV_vs_WT_F07.15804.15804.3 0.427 14/64 R.KYGGISTASVDFEQPTR.D sp|P98175|RBM10_HUMAN 1 1854.9112 12.24 102588 15804 3 1854.907302 619.311 RNA-binding protein 10 OS=Homo sapiens OX=9606 GN=RBM10 PE=1 SV=3 6.07 2712.5 - 673119 - - - -2.0971 - 1.919 0.077 - 121.8 1 2 0 -0.0039 17 0 0 0 1.66E+07 1.35E+06 - - - 1.0441 0.9999 221125_WJC_METTL3_EV_vs_WT_F07.15808.15808.3 2.84E-08 23/56 K.SESQKEDPFNIAEPR.V sp|Q9Y2X9|ZN281_HUMAN 1 1745.822 1.21 102590 15808 3 1745.817455 582.948 Zinc finger protein 281 OS=Homo sapiens OX=9606 GN=ZNF281 PE=1 SV=1 4.41 2713 - 1.14E+06 - - - -2.628 - 3.449 0.585 - 722.7 1 2 1 -0.0046 15 0 0 0 1.25E+08 1.04E+08 - - - 8.2915 0.9998 221125_WJC_METTL3_EV_vs_WT_F07.15809.15809.3 2.40E-05 17/72 R.DTSVEGSEMVPGKVELQEK.V "sp|P18754|RCC1_HUMAN,tr|C9JQZ4|C9JQZ4_HUMAN,tr|C9J3R0|C9J3R0_HUMAN,tr|C9JMJ4|C9JMJ4_HUMAN,tr|C9JW69|C9JW69_HUMAN,tr|C9JRH2|C9JRH2_HUMAN" 6 2060.9936 0.73 102591 15809 3 2060.995218 688.0051 Regulator of chromosome condensation OS=Homo sapiens OX=9606 GN=RCC1 PE=1 SV=1 4.25 2713.2 - 910257 - - - 0.7846 - 2.504 0.457 - 239.6 1 2 1 0.0016 19 0 0 0 1.74E+07 2.38E+07 - - - 5.8897 0.9999 221125_WJC_METTL3_EV_vs_WT_F07.15812.15812.3 0.0131 18/44 R.HLREYQDLLNVK.M "sp|P08670|VIME_HUMAN,sp|P17661|DESM_HUMAN,sp|Q16352|AINX_HUMAN,sp|P07197|NFM_HUMAN,tr|B0YJC5|B0YJC5_HUMAN,tr|B0YJC4|B0YJC4_HUMAN,tr|E7ESP9|E7ESP9_HUMAN,tr|E7EMV2|E7EMV2_HUMAN" 8 1526.8205 1.73 102594 15812 3 1526.819102 509.9475 Vimentin OS=Homo sapiens OX=9606 GN=VIM PE=1 SV=4 6.75 2713.6 - 511567 - - - -0.9327 - 3.704 0.449 - 470.2 1 2 1 -0.0014 12 0 0 0 2.26E+07 1.31E+07 - - - 7.175 0.9995 221125_WJC_METTL3_EV_vs_WT_F07.15816.15816.4 0.00653 14/90 K.YSHLQPGDHLTDITLK.V "sp|Q15046|SYK_HUMAN,tr|H3BVA8|H3BVA8_HUMAN" 2 1836.937 1.67 102596 15816 4 1836.936018 460.2415 Lysine--tRNA ligase OS=Homo sapiens OX=9606 GN=KARS1 PE=1 SV=3 5.98 2714 - 1.44E+06 - - - -0.5417 - 2.271 0.332 - 109.2 1 2 0 -0.001 16 0 0 0 7.52E+07 4.50E+07 - - - 2.4044 1 221125_WJC_METTL3_EV_vs_WT_F07.15820.15820.2 1.58E-08 30-Dec K.FSVC[160.03]VLGDQQHC[160.03]DEAK[136.11].A sp|P62906|RL10A_HUMAN 1 1899.8335 0.81 102600 15820 2 1899.831153 950.924 60S ribosomal protein L10a OS=Homo sapiens OX=9606 GN=RPL10A PE=1 SV=2 4.54 2714.6 - 469204 - - - -1.2264 - 2.609 0.629 - 410.5 1 2 0 -0.0023 16 0 0 0 6.63E+06 8.23E+06 - - - 6.0437 0.9997 221125_WJC_METTL3_EV_vs_WT_F07.15823.15823.3 3.24E-06 Nov-56 R.ADTQTYQPYNK[136.11]DWIK[136.11].E sp|P84090|ERH_HUMAN 1 1885.9181 2.35 102602 15823 3 1885.916032 629.6467 Enhancer of rudimentary homolog OS=Homo sapiens OX=9606 GN=ERH PE=1 SV=1 6 2714.9 - 4.26E+07 - - - -1.1114 - 2.277 0.456 - 178.7 1 2 1 -0.0021 15 0 0 0 2.09E+09 8.93E+08 - - - 5.7705 1 221125_WJC_METTL3_EV_vs_WT_F07.15825.15825.3 3.10E-12 16/56 K.SESQK[136.11]EDPFNIAEPR[166.11].V sp|Q9Y2X9|ZN281_HUMAN 1 1763.8445 1.52 102603 15825 3 1763.839453 588.9554 Zinc finger protein 281 OS=Homo sapiens OX=9606 GN=ZNF281 PE=1 SV=1 4.41 2715.1 - 2.02E+06 - - - -2.8687 - 3.191 0.651 - 317.1 1 2 1 -0.0051 15 0 0 0 1.24E+08 8.14E+07 - - - 8.8243 0.9998 221125_WJC_METTL3_EV_vs_WT_F07.15827.15827.4 0.00139 Oct-90 K.TDVSTEHPPFYYNIHR[166.11].H sp|Q7Z2T5|TRM1L_HUMAN 1 1984.9307 0.56 102605 15827 4 1984.929425 497.24 TRMT1-like protein OS=Homo sapiens OX=9606 GN=TRMT1L PE=1 SV=2 5.92 2715.3 - 1.31E+06 - - - -0.6398 - 2.235 0.377 - 107.8 1 2 0 -0.0013 16 0 0 0 1.53E+07 2.75E+07 - - - 2.7904 1 221125_WJC_METTL3_EV_vs_WT_F07.15832.15832.3 3.89E-07 14/60 K.FSVC[160.03]VLGDQQHC[160.03]DEAK.A sp|P62906|RL10A_HUMAN 1 1891.8193 0.92 102608 15832 3 1891.816297 631.6137 60S ribosomal protein L10a OS=Homo sapiens OX=9606 GN=RPL10A PE=1 SV=2 4.54 2716 - 1.61E+07 - - - -1.5784 - 2.861 0.625 - 271.6 1 2 0 -0.003 16 0 0 0 3.05E+08 3.31E+08 - - - 8.2045 1 221125_WJC_METTL3_EV_vs_WT_F07.15836.15836.2 1.81E-09 14/28 R.SGDSEVYQLGDVSQK.T "sp|Q04837|SSBP_HUMAN,tr|C9K0U8|C9K0U8_HUMAN,tr|A0A0G2JLD8|A0A0G2JLD8_HUMAN,tr|E7EUY5|E7EUY5_HUMAN" 4 1610.7424 1.87 102612 15836 2 1610.742709 806.3785 "Single-stranded DNA-binding protein, mitochondrial OS=Homo sapiens OX=9606 GN=SSBP1 PE=1 SV=1" 4.03 2716.4 - 430307 - - - 0.1949 - 2.86 0.675 - 812.6 1 2 0 0.0003 15 0 0 0 1.58E+07 8.47E+06 - - - 6.6099 0.9999 221125_WJC_METTL3_EV_vs_WT_F07.15840.15840.3 0.000927 13/44 R.K[136.11]ALDDMISTLK[136.11]K[136.11].L "sp|P49368|TCPG_HUMAN,tr|E9PM09|E9PM09_HUMAN,tr|Q5SZW8|Q5SZW8_HUMAN,tr|E9PRC8|E9PRC8_HUMAN,tr|B4DUR8|B4DUR8_HUMAN,tr|E9PQ35|E9PQ35_HUMAN,tr|Q5SZX6|Q5SZX6_HUMAN" 7 1385.8014 0.18 102614 15840 3 1385.799049 462.9411 T-complex protein 1 subunit gamma OS=Homo sapiens OX=9606 GN=CCT3 PE=1 SV=4 8.5 2716.9 - 2.82E+06 - - - -1.7232 - 2.569 0.445 - 198.4 1 2 0 -0.0024 12 0 0 0 9.79E+06 5.56E+07 - - - 6.1159 0.9999 221125_WJC_METTL3_EV_vs_WT_F07.15841.15841.4 4.18E-09 17/84 R.LK[136.11]NEIPNSHILDQYR[166.11].N sp|P35520|CBS_HUMAN 1 1856.9864 2.66 102615 15841 4 1856.982303 465.2539 Cystathionine beta-synthase OS=Homo sapiens OX=9606 GN=CBS PE=1 SV=2 6.75 2717 - 1.18E+06 - - - -2.188 - 3.262 0.607 - 217.5 1 2 1 -0.0041 15 0 0 0 8.59E+07 3.23E+07 - - - 4.9313 1 221125_WJC_METTL3_EV_vs_WT_F07.15842.15842.4 6.21E-05 18/90 R.ETNLDSLPLVDTHSKR.T sp|P08670|VIME_HUMAN 1 1823.9377 1.43 102616 15842 4 1823.9372 456.9917 Vimentin OS=Homo sapiens OX=9606 GN=VIM PE=1 SV=4 5.38 2717.1 - 3.09E+06 - - - -0.2966 - 3.101 0.504 - 345.3 1 2 0 -0.0005 16 0 0 0 1.22E+08 8.54E+07 - - - 4.0113 1 221125_WJC_METTL3_EV_vs_WT_F07.15844.15844.3 1.93E-13 23/92 R.VLFR[166.11]PSDTANSSNQDALSSNTSLK[136.11].L sp|Q8N4V1|EMC5_HUMAN 1 2569.2739 1.14 102618 15844 3 2569.273943 857.4319 ER membrane protein complex subunit 5 OS=Homo sapiens OX=9606 GN=MMGT1 PE=1 SV=1 5.93 2717.3 - 1.03E+06 - - - 0.0191 - 4.268 0.636 - 587.7 1 2 0 0.0001 24 0 0 0 5.04E+07 4.40E+07 - - - 9.0012 1 221125_WJC_METTL3_EV_vs_WT_F07.15845.15845.3 2.08E-06 22/60 R.ETNLDSLPLVDTHSK[136.11]R[166.11].T sp|P08670|VIME_HUMAN 1 1841.9602 1.35 102619 15845 3 1841.962524 614.994 Vimentin OS=Homo sapiens OX=9606 GN=VIM PE=1 SV=4 5.38 2717.4 - 992124 - - - 1.2557 - 3.474 0.483 - 672.1 1 2 0 0.0023 16 0 0 0 5.84E+07 4.33E+07 - - - 7.1196 1 221125_WJC_METTL3_EV_vs_WT_F07.15846.15846.3 3.36E-15 24/92 R.VLFRPSDTANSSNQDALSSNTSLK.L sp|Q8N4V1|EMC5_HUMAN 1 2551.2514 1.15 102620 15846 3 2551.253899 851.4244 ER membrane protein complex subunit 5 OS=Homo sapiens OX=9606 GN=MMGT1 PE=1 SV=1 5.93 2717.5 - 964566 - - - 0.9701 - 4.292 0.694 - 602.3 1 2 0 0.0025 24 0 0 0 5.04E+07 4.37E+07 - - - 9.6602 1 221125_WJC_METTL3_EV_vs_WT_F07.15847.15847.2 5.62E-09 15/30 K.FSVC[160.03]VLGDQQHC[160.03]DEAK.A sp|P62906|RL10A_HUMAN 1 1891.8193 0.81 102621 15847 2 1891.811918 946.9169 60S ribosomal protein L10a OS=Homo sapiens OX=9606 GN=RPL10A PE=1 SV=2 4.54 2717.7 - 517389 - - - -3.8931 - 2.862 0.638 - 719 1 2 0 -0.0074 16 0 0 0 6.63E+06 8.23E+06 - - - 6.3362 1 221125_WJC_METTL3_EV_vs_WT_F07.15851.15851.4 0.0025 13/84 K.THINIVVIGHVDSGK[136.11].S "sp|Q05639|EF1A2_HUMAN,sp|P68104|EF1A1_HUMAN,sp|Q5VTE0|EF1A3_HUMAN,tr|A0A2R8Y488|A0A2R8Y488_HUMAN,tr|A0A2R8YDN5|A0A2R8YDN5_HUMAN,tr|A0A7I2V659|A0A7I2V659_HUMAN,tr|A0A7I2V3H3|A0A7I2V3H3_HUMAN,tr|Q5JR01|Q5JR01_HUMAN,tr|A0A2U3TZH3|A0A2U3TZH3_HUMAN,tr|A0A7I2V5N4|A0A7I2V5N4_HUMAN,tr|A0A087WVQ9|A0A087WVQ9_HUMAN,tr|A6PW80|A6PW80_HUMAN,tr|A0A087WV01|A0A087WV01_HUMAN,tr|A0A2R8Y660|A0A2R8Y660_HUMAN,tr|A0A6Q8PFK6|A0A6Q8PFK6_HUMAN" 15 1595.8875 0.62 102623 15851 4 1595.886748 399.9791 Elongation factor 1-alpha 2 OS=Homo sapiens OX=9606 GN=EEF1A2 PE=1 SV=1 6.61 2718.2 - 234313 - - - -0.4649 - 2.805 0.478 - 128.2 1 2 0 -0.0007 15 0 0 0 2.92E+06 4.70E+06 - - - 3.7554 0.9998 221125_WJC_METTL3_EV_vs_WT_F07.15855.15855.3 6.67E-06 Dec-56 R.LK[136.11]NEIPNSHILDQYR[166.11].N sp|P35520|CBS_HUMAN 1 1856.9864 2.05 102626 15855 3 1856.988945 620.0027 Cystathionine beta-synthase OS=Homo sapiens OX=9606 GN=CBS PE=1 SV=2 6.75 2718.6 - 981820 - - - 1.3888 - 2.701 0.473 - 106.8 1 2 1 0.0026 15 0 0 0 5.49E+07 2.68E+07 - - - 6.4055 1 221125_WJC_METTL3_EV_vs_WT_F07.15856.15856.4 6.86E-06 14/90 K.TDVSTEHPPFYYNIHR.H sp|Q7Z2T5|TRM1L_HUMAN 1 1974.9224 0.53 102627 15856 4 1974.922546 494.7379 TRMT1-like protein OS=Homo sapiens OX=9606 GN=TRMT1L PE=1 SV=2 5.92 2718.7 - 834470 - - - 0.0613 - 2.957 0.491 - 135.3 1 2 0 0.0001 16 0 0 0 1.67E+07 3.12E+07 - - - 3.8815 1 221125_WJC_METTL3_EV_vs_WT_F07.15857.15857.3 2.17E-10 17/60 R.HWILPQDYDHAQAEAR[166.11].H sp|Q15293|RCN1_HUMAN 1 1958.9263 0.79 102628 15857 3 1958.923887 653.9827 Reticulocalbin-1 OS=Homo sapiens OX=9606 GN=RCN1 PE=1 SV=1 5.21 2718.8 - 578073 - - - -1.2211 - 3.744 0.63 - 445.6 1 2 0 -0.0024 16 0 0 0 8.58E+06 1.08E+07 - - - 8.9506 1 221125_WJC_METTL3_EV_vs_WT_F07.15858.15858.3 4.32E-11 18/60 R.HWILPQDYDHAQAEAR.H sp|Q15293|RCN1_HUMAN 1 1948.918 0.79 102629 15858 3 1948.920923 650.6466 Reticulocalbin-1 OS=Homo sapiens OX=9606 GN=RCN1 PE=1 SV=1 5.21 2719 - 546791 - - - 1.4952 - 3.56 0.623 - 505.4 1 2 0 0.0029 16 0 0 0 8.58E+06 1.08E+07 - - - 8.7431 1 221125_WJC_METTL3_EV_vs_WT_F07.15862.15862.4 6.44E-08 15/84 K.TFK[136.11]PAIQELK[136.11]PPTYK[136.11].L "sp|P82650|RT22_HUMAN,tr|G5E9W7|G5E9W7_HUMAN,tr|A0A7P0MKV3|A0A7P0MKV3_HUMAN,tr|H7C5F2|H7C5F2_HUMAN,tr|H7C5H3|H7C5H3_HUMAN" 5 1784.0299 1.17 102631 15862 4 1784.027853 447.0147 "28S ribosomal protein S22, mitochondrial OS=Homo sapiens OX=9606 GN=MRPS22 PE=1 SV=1" 9.52 2719.5 - 1.14E+06 - - - -1.1239 - 2.76 0.536 - 105.9 1 2 0 -0.002 15 0 0 0 1.69E+07 1.45E+07 - - - 4.254 1 221125_WJC_METTL3_EV_vs_WT_F07.15866.15866.4 1.75E-06 18/96 K.ELEGWEPDDDPIEEHKK.H "sp|O15392|BIRC5_HUMAN,tr|A0A0B4J1S3|A0A0B4J1S3_HUMAN" 2 2064.9276 3.89 102635 15866 4 2064.929684 517.2392 Baculoviral IAP repeat-containing protein 5 OS=Homo sapiens OX=9606 GN=BIRC5 PE=1 SV=3 4.12 2719.9 - 811151 - - - 0.9947 - 3.171 0.545 - 295.7 1 2 0 0.0021 17 0 0 0 1.85E+07 4.75E+06 - - - 4.3698 0.9995 221125_WJC_METTL3_EV_vs_WT_F07.15867.15867.3 9.61E-07 14/48 R.IKDYHSYMLQISK.Q sp|O94864|ST65G_HUMAN 1 1624.8283 1.17 102636 15867 3 1624.827255 542.6167 STAGA complex 65 subunit gamma OS=Homo sapiens OX=9606 GN=SUPT7L PE=1 SV=1 8.44 2720 - 743016 - - - -0.6518 - 2.402 0.37 - 189.9 1 2 1 -0.0011 13 0 0 0 1.09E+07 9.33E+06 - - - 5.0408 1 221125_WJC_METTL3_EV_vs_WT_F07.15868.15868.3 3.63E-10 21/76 K.DILLQQQQQLGHGGPEAAPR.A sp|Q7Z5L9|I2BP2_HUMAN 1 2155.1134 1.84 102637 15868 3 2155.112784 719.3784 Interferon regulatory factor 2-binding protein 2 OS=Homo sapiens OX=9606 GN=IRF2BP2 PE=1 SV=2 5.32 2720.1 - 704184 - - - -0.2923 - 3.801 0.63 - 440.9 1 2 0 -0.0006 20 0 0 0 8.87E+06 4.82E+06 - - - 8.8031 1 221125_WJC_METTL3_EV_vs_WT_F07.15869.15869.3 2.40E-06 14/60 K.TDVSTEHPPFYYNIHR[166.11].H sp|Q7Z2T5|TRM1L_HUMAN 1 1984.9307 0.86 102638 15869 3 1984.928261 662.6508 TRMT1-like protein OS=Homo sapiens OX=9606 GN=TRMT1L PE=1 SV=2 5.92 2720.3 - 689854 - - - -1.2262 - 2.766 0.537 - 260 1 2 0 -0.0024 16 0 0 0 9.48E+06 1.11E+07 - - - 7.1369 0.996 221125_WJC_METTL3_EV_vs_WT_F07.15873.15873.4 0.106 Aug-72 R.IKDYHSYMLQISK.Q sp|O94864|ST65G_HUMAN 1 1624.8283 1.31 102642 15873 4 1624.826152 407.2144 STAGA complex 65 subunit gamma OS=Homo sapiens OX=9606 GN=SUPT7L PE=1 SV=1 8.44 2720.8 - 359968 - - - -1.3306 - 1.587 0.305 - 51.7 1 2 1 -0.0022 13 0 0 0 6.30E+06 4.79E+06 - - - 2.0514 0.9999 221125_WJC_METTL3_EV_vs_WT_F07.15874.15874.3 0.000203 Nov-40 K.QQHVIETLIGK[136.11].K "sp|P48643|TCPE_HUMAN,tr|E9PCA1|E9PCA1_HUMAN,tr|B7ZAR1|B7ZAR1_HUMAN,tr|E7ENZ3|E7ENZ3_HUMAN" 4 1272.7281 0.6 102643 15874 3 1272.726849 425.25 T-complex protein 1 subunit epsilon OS=Homo sapiens OX=9606 GN=CCT5 PE=1 SV=1 6.75 2720.9 - 355265 - - - -1.0112 - 1.99 0.447 - 203.8 1 2 0 -0.0013 11 0 0 0 5.18E+06 8.63E+06 - - - 5.4781 0.9994 221125_WJC_METTL3_EV_vs_WT_F07.15876.15876.2 5.61E-05 Aug-32 K.ANELPQPPVPEPANAGK[136.11].R "sp|P78347|GTF2I_HUMAN,tr|A0A494C1K3|A0A494C1K3_HUMAN" 2 1735.8984 1.93 102645 15876 2 1735.894807 868.9565 General transcription factor II-I OS=Homo sapiens OX=9606 GN=GTF2I PE=1 SV=2 4.53 2721.2 - 250370 - - - -2.098 - 1.754 0.465 - 133.4 1 2 0 -0.0036 17 0 0 0 9.07E+06 4.70E+06 - - - 3.8558 1 221125_WJC_METTL3_EV_vs_WT_F07.15881.15881.2 1.70E-05 15/24 R.FSGSGSGTDFTLK.L "sp|A2NJV5|KV229_HUMAN,sp|A0A087WW87|KV240_HUMAN,sp|P06310|KV230_HUMAN,sp|A0A075B6S2|KVD29_HUMAN,sp|P01614|KVD40_HUMAN,sp|P01615|KVD28_HUMAN,sp|A0A075B6S6|KVD30_HUMAN,sp|A0A075B6P5|KV228_HUMAN,sp|A0A0A0MRZ7|KVD26_HUMAN" 9 1302.6092 999 102648 15881 2 1302.610515 652.3119 Immunoglobulin kappa variable 2-29 OS=Homo sapiens OX=9606 GN=IGKV2-29 PE=3 SV=2 5.84 2721.7 - 3.44E+06 - - - 1.0126 - 2.899 0.663 - 493.8 1 2 0 0.0013 13 0 0 0 6.89E+08 0.00E+00 - - - 6.6692 1 221125_WJC_METTL3_EV_vs_WT_F07.15882.15882.3 2.72E-10 24/84 A.FASSLVSGLNSSASEPAK[136.11]EPAK[136.11].K "sp|Q86U44|MTA70_HUMAN,tr|F5H6D8|F5H6D8_HUMAN,tr|H0YFV6|H0YFV6_HUMAN,tr|B4DTN4|B4DTN4_HUMAN" 4 2192.1296 0 102649 15882 3 2192.128002 731.7171 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 6.14 2721.9 - 933000 - - - -0.7189 - 4.431 0.625 - 604.5 1 1 1 -0.0016 22 0 0 0 2.90E+06 7.19E+08 - - - 9.037 0.9999 221125_WJC_METTL3_EV_vs_WT_F07.15884.15884.4 0.00571 Nov-90 R.HWILPQDYDHAQAEAR[166.11].H sp|Q15293|RCN1_HUMAN 1 1958.9263 0.77 102651 15884 4 1958.92893 490.7388 Reticulocalbin-1 OS=Homo sapiens OX=9606 GN=RCN1 PE=1 SV=1 5.21 2722.1 - 385791 - - - 1.3533 - 2.105 0.409 - 98.2 1 2 0 0.0027 16 0 0 0 7.78E+06 1.01E+07 - - - 3.0474 0.9999 221125_WJC_METTL3_EV_vs_WT_F07.15885.15885.3 0.000118 Sep-32 R.VVHIMDFQR.G "sp|P43243|MATR3_HUMAN,tr|D6RE02|D6RE02_HUMAN,tr|B3KM87|B3KM87_HUMAN,tr|A8MXP9|A8MXP9_HUMAN,tr|D6RAY2|D6RAY2_HUMAN,tr|D6R991|D6R991_HUMAN,tr|A0A0R4J2E8|A0A0R4J2E8_HUMAN,tr|D6RAM9|D6RAM9_HUMAN,tr|D6RIA2|D6RIA2_HUMAN,tr|H0Y8T4|H0Y8T4_HUMAN,tr|D6REM6|D6REM6_HUMAN,tr|D6RBI2|D6RBI2_HUMAN" 12 1143.5859 1.16 102652 15885 3 1143.585471 382.2026 Matrin-3 OS=Homo sapiens OX=9606 GN=MATR3 PE=1 SV=2 6.71 2722.3 - 243642 - - - -0.3743 - 1.665 0.475 - 152.3 1 2 0 -0.0004 9 0 0 0 1.27E+07 1.10E+07 - - - 5.3722 0.9999 221125_WJC_METTL3_EV_vs_WT_F07.15889.15889.4 2.96E-09 14/102 R.HGLLVPNNTTDQELQHIR[166.11].N "sp|P56537|IF6_HUMAN,tr|B7ZBH1|B7ZBH1_HUMAN" 2 2094.0846 3.91 102654 15889 4 2094.092789 524.5284 Eukaryotic translation initiation factor 6 OS=Homo sapiens OX=9606 GN=EIF6 PE=1 SV=1 5.99 2722.7 - 463382 - - - 3.9249 - 2.991 0.544 - 195.4 1 2 0 0.0082 18 0 0 0 4.44E+07 1.14E+07 - - - 4.334 0.9998 221125_WJC_METTL3_EV_vs_WT_F07.15891.15891.3 0.0216 Dec-56 K.TFK[136.11]PAIQELK[136.11]PPTYK[136.11].L "sp|P82650|RT22_HUMAN,tr|G5E9W7|G5E9W7_HUMAN,tr|A0A7P0MKV3|A0A7P0MKV3_HUMAN,tr|H7C5F2|H7C5F2_HUMAN,tr|H7C5H3|H7C5H3_HUMAN" 5 1784.0299 1.46 102656 15891 3 1784.032837 595.6839 "28S ribosomal protein S22, mitochondrial OS=Homo sapiens OX=9606 GN=MRPS22 PE=1 SV=1" 9.52 2723 - 542783 - - - 1.6698 - 2.028 0.417 - 81.5 1 2 0 0.003 15 0 0 0 2.26E+07 1.56E+07 - - - 5.0333 0.9941 221125_WJC_METTL3_EV_vs_WT_F07.15894.15894.4 0.00923 13/90 R.HWILPQDYDHAQAEAR.H sp|Q15293|RCN1_HUMAN 1 1948.918 0.74 102659 15894 4 1948.923658 488.2368 Reticulocalbin-1 OS=Homo sapiens OX=9606 GN=RCN1 PE=1 SV=1 5.21 2723.4 - 318022 - - - 2.8985 - 1.913 0.265 - 137.4 1 2 0 0.0056 16 0 0 0 7.02E+06 9.51E+06 - - - 1.7595 0.9913 221125_WJC_METTL3_EV_vs_WT_F07.15896.15896.4 0.0238 14/102 K.VTFHIEPYSNRDDQNMYK.N sp|Q5SRI9|MANEA_HUMAN 1 2256.027 1.33 102661 15896 4 2256.028209 565.014 "Glycoprotein endo-alpha-1,2-mannosidase OS=Homo sapiens OX=9606 GN=MANEA PE=1 SV=1" 5.38 2723.6 - 264952 - - - 0.5505 - 2.074 0.259 - 97.7 1 2 1 0.0012 18 0 0 0 6.85E+06 5.17E+06 - - - 1.7299 1 221125_WJC_METTL3_EV_vs_WT_F07.15897.15897.2 5.31E-09 28-Dec K.SESQKEDPFNIAEPR.V sp|Q9Y2X9|ZN281_HUMAN 1 1745.822 2.22 102662 15897 2 1745.826575 873.9183 Zinc finger protein 281 OS=Homo sapiens OX=9606 GN=ZNF281 PE=1 SV=1 4.41 2723.8 - 130005 - - - 2.5959 - 2.502 0.619 - 380.1 1 2 1 0.0045 15 0 0 0 2.02E+06 9.10E+05 - - - 5.8662 0.9998 221125_WJC_METTL3_EV_vs_WT_F07.15899.15899.3 2.25E-05 15/44 K.SK[136.11]LPK[136.11]PVQDLIK[136.11].M sp|P09874|PARP1_HUMAN 1 1388.8817 1.14 102663 15899 3 1388.882648 463.9679 Poly [ADP-ribose] polymerase 1 OS=Homo sapiens OX=9606 GN=PARP1 PE=1 SV=4 9.7 2724 - 1.41E+06 - - - 0.6559 - 2.599 0.466 - 177.1 1 2 1 0.0009 12 0 0 0 8.62E+07 7.58E+07 - - - 6.3827 0.9999 221125_WJC_METTL3_EV_vs_WT_F07.15901.15901.3 5.60E-06 Oct-32 R.VVHIMDFQR[166.11].G "sp|P43243|MATR3_HUMAN,tr|D6RE02|D6RE02_HUMAN,tr|B3KM87|B3KM87_HUMAN,tr|A8MXP9|A8MXP9_HUMAN,tr|D6RAY2|D6RAY2_HUMAN,tr|D6R991|D6R991_HUMAN,tr|A0A0R4J2E8|A0A0R4J2E8_HUMAN,tr|D6RAM9|D6RAM9_HUMAN,tr|D6RIA2|D6RIA2_HUMAN,tr|H0Y8T4|H0Y8T4_HUMAN,tr|D6REM6|D6REM6_HUMAN,tr|D6RBI2|D6RBI2_HUMAN" 12 1153.5942 1.17 102664 15901 3 1153.594213 385.5387 Matrin-3 OS=Homo sapiens OX=9606 GN=MATR3 PE=1 SV=2 6.71 2724.2 - 574298 - - - 0.0381 - 1.922 0.465 - 165.6 1 2 0 0 9 0 0 0 1.26E+07 1.07E+07 - - - 5.6934 0.9999 221125_WJC_METTL3_EV_vs_WT_F07.15902.15902.3 0.000579 16/112 R.AAAAPGASPSPGGDAAWSEAGPGPR[166.11]PLAR[166.11].S "sp|P52701|MSH6_HUMAN,tr|F8W7G9|F8W7G9_HUMAN,tr|F8WAX8|F8WAX8_HUMAN" 3 2661.3163 1.01 102665 15902 3 2661.316727 888.1127 DNA mismatch repair protein Msh6 OS=Homo sapiens OX=9606 GN=MSH6 PE=1 SV=2 6.12 2724.4 - 366043 - - - 0.1789 - 2.295 0.46 - 145.2 1 2 0 0.0005 29 0 0 0 1.66E+07 1.63E+07 - - - 5.5796 0.9997 221125_WJC_METTL3_EV_vs_WT_F07.15903.15903.2 1.81E-05 20-Sep R.NPEAALSPTFR[166.11].S "sp|Q86U44|MTA70_HUMAN,tr|B4E349|B4E349_HUMAN,tr|F5H6D8|F5H6D8_HUMAN,tr|B4DTN4|B4DTN4_HUMAN" 4 1211.6174 0.02 102666 15903 2 1211.619983 606.816 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 6 2724.4 - 1.81E+06 - - - 2.1261 - 2.32 0.488 - 451.8 1 2 0 0.0026 11 0 0 0 9.54E+06 4.80E+08 - - - 4.9212 0.997 221125_WJC_METTL3_EV_vs_WT_F07.15905.15905.3 0.046 Sep-44 R.GQPIYIQFSNHK.E "sp|P26599|PTBP1_HUMAN,tr|A0A6Q8PEX4|A0A6Q8PEX4_HUMAN,tr|A0A0U1RRM4|A0A0U1RRM4_HUMAN,tr|A6NLN1|A6NLN1_HUMAN,tr|K7EKJ7|K7EKJ7_HUMAN,tr|K7ES59|K7ES59_HUMAN,tr|A0A7I2V4H6|A0A7I2V4H6_HUMAN,tr|A0A7I2V621|A0A7I2V621_HUMAN" 8 1430.7306 0.98 102668 15905 3 1430.73208 477.9175 Polypyrimidine tract-binding protein 1 OS=Homo sapiens OX=9606 GN=PTBP1 PE=1 SV=1 8.6 2724.7 - 580417 - - - 1.0002 - 1.794 0.221 - 100.6 1 2 0 0.0014 12 0 0 0 2.12E+07 2.16E+07 - - - 2.6235 1 221125_WJC_METTL3_EV_vs_WT_F07.15909.15909.3 1.64E-07 13/116 R.EVPEPGTAASGPGEGEGSEYGASGEDALSR[166.11].L "sp|Q9C0C7|AMRA1_HUMAN,tr|H0YE34|H0YE34_HUMAN,tr|A0A075B6T1|A0A075B6T1_HUMAN" 3 2872.251 0.7 102672 15909 3 2872.250647 958.4243 Activating molecule in BECN1-regulated autophagy protein 1 OS=Homo sapiens OX=9606 GN=AMBRA1 PE=1 SV=2 3.77 2725.2 - 268714 - - - -0.1365 - 2.288 0.695 - 100.9 1 2 0 -0.0004 30 0 0 0 1.23E+06 1.76E+06 - - - 8.1926 0.9999 221125_WJC_METTL3_EV_vs_WT_F07.15910.15910.3 5.19E-07 14/68 R.SPQPDPVGTPTIFK[136.11]PQSK[136.11].R sp|P46013|KI67_HUMAN 1 1939.0386 1.28 102673 15910 3 1939.040096 647.3535 Proliferation marker protein Ki-67 OS=Homo sapiens OX=9606 GN=MKI67 PE=1 SV=2 8.31 2725.3 - 167208 - - - 0.7829 - 2.598 0.419 - 239.8 1 2 0 0.0015 18 0 0 0 1.20E+07 9.38E+06 - - - 5.5884 1 221125_WJC_METTL3_EV_vs_WT_F07.15913.15913.3 6.67E-08 15/112 R.AAAAPGASPSPGGDAAWSEAGPGPRPLAR.S "sp|P52701|MSH6_HUMAN,tr|F8W7G9|F8W7G9_HUMAN,tr|F8WAX8|F8WAX8_HUMAN" 3 2641.2997 1.01 102674 15913 3 2641.300487 881.4405 DNA mismatch repair protein Msh6 OS=Homo sapiens OX=9606 GN=MSH6 PE=1 SV=2 6.12 2725.7 - 693912 - - - 0.2938 - 2.627 0.592 - 125.9 1 2 0 0.0008 29 0 0 0 1.66E+07 1.63E+07 - - - 7.3621 0.9998 221125_WJC_METTL3_EV_vs_WT_F07.15914.15914.4 9.91E-05 15/120 R.LTVNYEQC[160.03]ASGVHGPEGFHYK.C "sp|P19525|E2AK2_HUMAN,tr|A0A7P0TAL9|A0A7P0TAL9_HUMAN,tr|A0A7P0Z4M0|A0A7P0Z4M0_HUMAN,tr|A0A7P0TBA9|A0A7P0TBA9_HUMAN" 4 2392.0906 1.58 102675 15914 4 2392.09216 599.0299 "Interferon-induced, double-stranded RNA-activated protein kinase OS=Homo sapiens OX=9606 GN=EIF2AK2 PE=1 SV=2" 6 2725.8 - 639095 - - - 0.6396 - 2.649 0.367 - 134.8 1 2 0 0.0015 21 0 0 0 6.54E+06 4.13E+06 - - - 2.742 0.9748 221125_WJC_METTL3_EV_vs_WT_F07.15916.15916.3 0.0591 Oct-44 R.GQPIYIQFSNHK[136.11].E "sp|P26599|PTBP1_HUMAN,tr|A0A6Q8PEX4|A0A6Q8PEX4_HUMAN,tr|A0A0U1RRM4|A0A0U1RRM4_HUMAN,tr|A6NLN1|A6NLN1_HUMAN,tr|K7EKJ7|K7EKJ7_HUMAN,tr|K7ES59|K7ES59_HUMAN,tr|A0A7I2V4H6|A0A7I2V4H6_HUMAN,tr|A0A7I2V621|A0A7I2V621_HUMAN" 8 1438.7448 1.01 102677 15916 3 1438.746092 480.5889 Polypyrimidine tract-binding protein 1 OS=Homo sapiens OX=9606 GN=PTBP1 PE=1 SV=1 8.6 2726 - 995618 - - - 0.8639 - 1.741 0.108 - 133.6 1 2 0 0.0012 12 0 0 0 2.10E+07 2.07E+07 - - - 1.2806 0.9999 221125_WJC_METTL3_EV_vs_WT_F07.15918.15918.4 0.000405 13/120 R.LTVNYEQC[160.03]ASGVHGPEGFHYK[136.11].C "sp|P19525|E2AK2_HUMAN,tr|A0A7P0TAL9|A0A7P0TAL9_HUMAN,tr|A0A7P0Z4M0|A0A7P0Z4M0_HUMAN,tr|A0A7P0TBA9|A0A7P0TBA9_HUMAN" 4 2400.1048 1.58 102679 15918 4 2400.10492 601.0335 "Interferon-induced, double-stranded RNA-activated protein kinase OS=Homo sapiens OX=9606 GN=EIF2AK2 PE=1 SV=2" 6 2726.3 - 412153 - - - 0.0375 - 2.923 0.397 - 105.5 1 2 0 0.0001 21 0 0 0 6.54E+06 4.13E+06 - - - 3.0361 1 221125_WJC_METTL3_EV_vs_WT_F07.15919.15919.3 5.03E-05 16/64 K.ANELPQPPVPEPANAGK[136.11].R "sp|P78347|GTF2I_HUMAN,tr|A0A494C1K3|A0A494C1K3_HUMAN" 2 1735.8984 2.35 102680 15919 3 1735.897396 579.6401 General transcription factor II-I OS=Homo sapiens OX=9606 GN=GTF2I PE=1 SV=2 4.53 2726.4 - 634795 - - - -0.6066 - 3.076 0.476 - 326.5 1 2 0 -0.0011 17 0 0 0 3.22E+07 1.37E+07 - - - 6.6853 1 221125_WJC_METTL3_EV_vs_WT_F07.15920.15920.3 1.74E-06 16/88 K.GNDTPLALESTNTEK[136.11]ETSLEETK[136.11].L sp|Q7Z6Z7|HUWE1_HUMAN 1 2522.2206 0.41 102681 15920 3 2522.22137 841.7475 E3 ubiquitin-protein ligase HUWE1 OS=Homo sapiens OX=9606 GN=HUWE1 PE=1 SV=3 4.14 2726.6 - 370029 - - - 0.2906 - 3.63 0.619 - 203.9 1 2 1 0.0007 23 0 0 0 4.60E+06 1.13E+07 - - - 8.4655 0.9998 221125_WJC_METTL3_EV_vs_WT_F07.15922.15922.3 0.0147 Nov-40 R.NPEAALSPTFR[166.11].S "sp|Q86U44|MTA70_HUMAN,tr|B4E349|B4E349_HUMAN,tr|F5H6D8|F5H6D8_HUMAN,tr|B4DTN4|B4DTN4_HUMAN" 4 1211.6174 0.01 102683 15922 3 1211.616505 404.8797 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 6 2726.8 - 263941 - - - -0.7445 - 2.08 0.342 - 263.8 1 2 0 -0.0009 11 0 0 0 1.71E+05 2.71E+07 - - - 4.4332 1 221125_WJC_METTL3_EV_vs_WT_F07.15926.15926.3 1.97E-07 17/60 R.HSIAQLDPEALGNIKK.L sp|Q53HL2|BOREA_HUMAN 1 1732.9472 1.44 102685 15926 3 1732.948507 578.6563 Borealin OS=Homo sapiens OX=9606 GN=CDCA8 PE=1 SV=2 6.75 2727.4 - 923193 - - - 0.7634 - 3.196 0.526 - 434.6 1 2 0 0.0013 16 0 0 0 2.97E+07 2.06E+07 - - - 7.3853 0.9999 221125_WJC_METTL3_EV_vs_WT_F07.15927.15927.3 0.00402 16/48 K.DR[166.11]LLASTLVHSVK[136.11].K "sp|Q9NYF8|BCLF1_HUMAN,tr|E9PKI6|E9PKI6_HUMAN,tr|A0A1W2PQ43|A0A1W2PQ43_HUMAN,tr|E9PK91|E9PK91_HUMAN,tr|E9PJA7|E9PJA7_HUMAN,tr|E9PK09|E9PK09_HUMAN,tr|E9PQN2|E9PQN2_HUMAN" 7 1455.8528 2.27 102686 15927 3 1455.854628 486.2916 Bcl-2-associated transcription factor 1 OS=Homo sapiens OX=9606 GN=BCLAF1 PE=1 SV=2 8.75 2727.5 - 654566 - - - 1.233 - 3.333 0.484 - 441.3 1 2 1 0.0018 13 0 0 0 2.35E+07 1.03E+07 - - - 7.1997 1 221125_WJC_METTL3_EV_vs_WT_F07.15928.15928.4 5.01E-07 19/90 R.HSIAQLDPEALGNIKK.L sp|Q53HL2|BOREA_HUMAN 1 1732.9472 1.59 102687 15928 4 1732.95012 434.2441 Borealin OS=Homo sapiens OX=9606 GN=CDCA8 PE=1 SV=2 6.75 2727.6 - 913114 - - - 1.6942 - 3.304 0.521 - 427.7 1 2 0 0.0029 16 0 0 0 2.45E+07 1.54E+07 - - - 4.181 0.9998 221125_WJC_METTL3_EV_vs_WT_F07.15929.15929.4 0.000194 12/108 R.GLLQDDAHPTLVTYADHSK[136.11].L "sp|Q86U44|MTA70_HUMAN,tr|F5H6D8|F5H6D8_HUMAN,tr|H0YFV6|H0YFV6_HUMAN,tr|B4DTN4|B4DTN4_HUMAN" 4 2088.0367 0.01 102688 15929 4 2088.036305 523.0165 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 5.13 2727.7 - 826595 - - - -0.205 - 2.35 0.387 - 151.3 1 2 0 -0.0004 19 0 0 0 7.00E+04 6.10E+06 - - - 2.8834 0.9999 221125_WJC_METTL3_EV_vs_WT_F07.15931.15931.4 9.71E-06 14/90 R.HSIAQLDPEALGNIK[136.11]K[136.11].L sp|Q53HL2|BOREA_HUMAN 1 1748.9756 1.72 102690 15931 4 1748.975793 438.2512 Borealin OS=Homo sapiens OX=9606 GN=CDCA8 PE=1 SV=2 6.75 2728 - 578803 - - - 0.1195 - 2.424 0.413 - 198.4 1 2 0 0.0002 16 0 0 0 2.44E+07 1.42E+07 - - - 3.1326 1 221125_WJC_METTL3_EV_vs_WT_F07.15933.15933.3 1.70E-06 15/68 R.SPQPDPVGTPTIFKPQSK.R sp|P46013|KI67_HUMAN 1 1923.0102 1.28 102692 15933 3 1923.014568 642.0107 Proliferation marker protein Ki-67 OS=Homo sapiens OX=9606 GN=MKI67 PE=1 SV=2 8.31 2728.2 - 460747 - - - 2.2829 - 3.234 0.493 - 251.3 1 2 0 0.0044 18 0 0 0 1.20E+07 9.38E+06 - - - 6.9579 0.9768 221125_WJC_METTL3_EV_vs_WT_F07.15935.15935.4 0.00504 Nov-90 R.LLHK[136.11]YPFILPHQQVDK[136.11].G "sp|Q9ULC4|MCTS1_HUMAN,tr|A0A3B3IRV3|A0A3B3IRV3_HUMAN" 2 1991.1328 0.38 102694 15935 4 1991.136052 498.7905 Malignant T-cell-amplified sequence 1 OS=Homo sapiens OX=9606 GN=MCTS1 PE=1 SV=1 8.51 2728.5 - 239930 - - - 1.6568 - 2.045 0.226 - 90.6 1 2 1 0.0033 16 0 0 0 1.93E+06 5.01E+06 - - - 1.4442 1 221125_WJC_METTL3_EV_vs_WT_F07.15936.15936.4 1.91E-08 21/168 R.AAAAPGASPSPGGDAAWSEAGPGPR[166.11]PLAR[166.11].S "sp|P52701|MSH6_HUMAN,tr|F8W7G9|F8W7G9_HUMAN,tr|F8WAX8|F8WAX8_HUMAN" 3 2661.3163 0.95 102695 15936 4 2661.321523 666.3363 DNA mismatch repair protein Msh6 OS=Homo sapiens OX=9606 GN=MSH6 PE=1 SV=2 6.12 2728.6 - 223704 - - - 1.981 - 3.494 0.576 - 261 1 2 0 0.0053 29 0 0 0 1.89E+06 2.00E+06 - - - 4.6236 0.9999 221125_WJC_METTL3_EV_vs_WT_F07.15940.15940.3 8.54E-06 19/48 K.DRLLASTLVHSVK.K "sp|Q9NYF8|BCLF1_HUMAN,tr|E9PKI6|E9PKI6_HUMAN,tr|A0A1W2PQ43|A0A1W2PQ43_HUMAN,tr|E9PK91|E9PK91_HUMAN,tr|E9PJA7|E9PJA7_HUMAN,tr|E9PK09|E9PK09_HUMAN,tr|E9PQN2|E9PQN2_HUMAN" 7 1437.8304 2.24 102697 15940 3 1437.831648 480.2841 Bcl-2-associated transcription factor 1 OS=Homo sapiens OX=9606 GN=BCLAF1 PE=1 SV=2 8.75 2729.1 - 2.05E+06 - - - 0.8937 - 3.136 0.46 - 589 1 2 1 0.0013 13 0 0 0 2.32E+07 1.03E+07 - - - 6.7671 0.9999 221125_WJC_METTL3_EV_vs_WT_F07.15941.15941.3 6.34E-08 17/56 K.TFKPAIQELKPPTYK.L "sp|P82650|RT22_HUMAN,tr|G5E9W7|G5E9W7_HUMAN,tr|A0A7P0MKV3|A0A7P0MKV3_HUMAN,tr|H7C5F2|H7C5F2_HUMAN,tr|H7C5H3|H7C5H3_HUMAN" 5 1759.9873 1.38 102698 15941 3 1759.992451 587.6697 "28S ribosomal protein S22, mitochondrial OS=Homo sapiens OX=9606 GN=MRPS22 PE=1 SV=1" 9.52 2729.2 - 1.13E+06 - - - 2.9506 - 2.677 0.541 - 250.2 1 2 0 0.0052 15 0 0 0 2.09E+07 1.52E+07 - - - 7.1396 1 221125_WJC_METTL3_EV_vs_WT_F07.15942.15942.3 6.53E-09 17/80 R.C[160.03]MLQDR[166.11]EDQSILC[160.03]TGESGAGK[136.11].T "sp|P35580|MYH10_HUMAN,tr|E7ERA5|E7ERA5_HUMAN" 2 2372.0525 0.71 102699 15942 3 2372.053223 791.6915 Myosin-10 OS=Homo sapiens OX=9606 GN=MYH10 PE=1 SV=3 4.32 2729.3 - 747140 - - - 0.2837 - 3.733 0.702 - 302.7 1 2 1 0.0007 21 0 0 0 8.08E+06 1.14E+07 - - - 9.5244 0.9996 221125_WJC_METTL3_EV_vs_WT_F07.15945.15945.3 7.47E-06 Nov-52 K.SFFDNISC[160.03]DDNRER.R "sp|Q8ND56|LS14A_HUMAN,tr|A0A096LP11|A0A096LP11_HUMAN,tr|A0A140TA76|A0A140TA76_HUMAN,tr|A0A0G2JQ95|A0A0G2JQ95_HUMAN" 4 1773.7377 1.14 102702 15945 3 1773.742652 592.2532 Protein LSM14 homolog A OS=Homo sapiens OX=9606 GN=LSM14A PE=1 SV=3 4.23 2729.7 - 465390 - - - 2.8138 - 2.034 0.574 - 125.7 1 2 1 0.005 14 0 0 0 7.58E+06 6.66E+06 - - - 6.825 0.9999 221125_WJC_METTL3_EV_vs_WT_F07.15950.15950.3 2.33E-07 20/48 K.DK[136.11]ADFC[160.03]IIHYAGK[136.11].V "sp|P35580|MYH10_HUMAN,sp|P35579|MYH9_HUMAN" 2 1552.7679 0.99 102705 15950 3 1552.770528 518.5966 Myosin-10 OS=Homo sapiens OX=9606 GN=MYH10 PE=1 SV=3 6.74 2730.3 - 871991 - - - 1.6931 - 3.052 0.578 - 443.3 1 2 1 0.0026 13 0 0 0 4.47E+07 4.51E+07 - - - 8.0087 1 221125_WJC_METTL3_EV_vs_WT_F07.15951.15951.3 4.40E-11 18/56 K.DVYKEHFQDDVFNEK.G "sp|P43490|NAMPT_HUMAN,tr|A0A7P0TB17|A0A7P0TB17_HUMAN,tr|A0A7P0T931|A0A7P0T931_HUMAN,tr|A0A7P0TAI8|A0A7P0TAI8_HUMAN,tr|A0A7P0T8L3|A0A7P0T8L3_HUMAN,tr|A0A7P0T941|A0A7P0T941_HUMAN,tr|A0A7P0T9F0|A0A7P0T9F0_HUMAN,tr|A0A7P0T973|A0A7P0T973_HUMAN,tr|A0A7P0T895|A0A7P0T895_HUMAN,tr|A0A7P0TBB7|A0A7P0TBB7_HUMAN,tr|A0A7P0TA73|A0A7P0TA73_HUMAN,tr|A0A0C4DFS8|A0A0C4DFS8_HUMAN,tr|A0A7P0Z4N0|A0A7P0Z4N0_HUMAN,tr|A0A7P0TAS5|A0A7P0TAS5_HUMAN,tr|A0A7P0T9I9|A0A7P0T9I9_HUMAN,tr|A0A7P0T8Z3|A0A7P0T8Z3_HUMAN,tr|A0A7P0T8R4|A0A7P0T8R4_HUMAN,tr|A0A7P0Z466|A0A7P0Z466_HUMAN,tr|A0A7P0T8D2|A0A7P0T8D2_HUMAN" 19 1911.8639 0.88 102706 15951 3 1911.868408 638.2952 Nicotinamide phosphoribosyltransferase OS=Homo sapiens OX=9606 GN=NAMPT PE=1 SV=1 4.43 2730.5 - 622660 - - - 2.3537 - 3.752 0.695 - 261.6 1 2 1 0.0045 15 0 0 0 6.77E+06 7.70E+06 - - - 9.7377 0.9968 221125_WJC_METTL3_EV_vs_WT_F07.15952.15952.4 0.000956 Dec-72 K.DK[136.11]ADFC[160.03]IIHYAGK[136.11].V "sp|P35580|MYH10_HUMAN,sp|P35579|MYH9_HUMAN" 2 1552.7679 0.87 102707 15952 4 1552.768101 389.1993 Myosin-10 OS=Homo sapiens OX=9606 GN=MYH10 PE=1 SV=3 6.74 2730.6 - 446362 - - - 0.1301 - 2.604 0.295 - 107.3 1 2 1 0.0002 13 0 0 0 1.94E+07 2.23E+07 - - - 2.1485 1 221125_WJC_METTL3_EV_vs_WT_F07.15957.15957.3 5.45E-11 16/60 R.HSIAQLDPEALGNIK[136.11]K[136.11].L sp|Q53HL2|BOREA_HUMAN 1 1748.9756 1.44 102710 15957 3 1748.973183 583.9991 Borealin OS=Homo sapiens OX=9606 GN=CDCA8 PE=1 SV=2 6.75 2731.3 - 1.14E+06 - - - -1.3728 - 3.48 0.601 - 453.4 1 2 0 -0.0024 16 0 0 0 2.97E+07 2.06E+07 - - - 8.4396 1 221125_WJC_METTL3_EV_vs_WT_F07.15958.15958.3 5.65E-09 19/56 K.DVYK[136.11]EHFQDDVFNEK[136.11].G "sp|P43490|NAMPT_HUMAN,tr|A0A7P0TB17|A0A7P0TB17_HUMAN,tr|A0A7P0T931|A0A7P0T931_HUMAN,tr|A0A7P0TAI8|A0A7P0TAI8_HUMAN,tr|A0A7P0T8L3|A0A7P0T8L3_HUMAN,tr|A0A7P0T941|A0A7P0T941_HUMAN,tr|A0A7P0T9F0|A0A7P0T9F0_HUMAN,tr|A0A7P0T973|A0A7P0T973_HUMAN,tr|A0A7P0T895|A0A7P0T895_HUMAN,tr|A0A7P0TBB7|A0A7P0TBB7_HUMAN,tr|A0A7P0TA73|A0A7P0TA73_HUMAN,tr|A0A0C4DFS8|A0A0C4DFS8_HUMAN,tr|A0A7P0Z4N0|A0A7P0Z4N0_HUMAN,tr|A0A7P0TAS5|A0A7P0TAS5_HUMAN,tr|A0A7P0T9I9|A0A7P0T9I9_HUMAN,tr|A0A7P0T8Z3|A0A7P0T8Z3_HUMAN,tr|A0A7P0T8R4|A0A7P0T8R4_HUMAN,tr|A0A7P0Z466|A0A7P0Z466_HUMAN,tr|A0A7P0T8D2|A0A7P0T8D2_HUMAN" 19 1927.8923 0.89 102711 15958 3 1927.892062 643.638 Nicotinamide phosphoribosyltransferase OS=Homo sapiens OX=9606 GN=NAMPT PE=1 SV=1 4.43 2731.4 - 599816 - - - -0.1276 - 3.519 0.655 - 310.9 1 2 1 -0.0002 15 0 0 0 6.94E+06 7.79E+06 - - - 9.1256 1 221125_WJC_METTL3_EV_vs_WT_F07.15959.15959.3 6.21E-05 20/48 K.DKADFC[160.03]IIHYAGK.V "sp|P35580|MYH10_HUMAN,sp|P35579|MYH9_HUMAN" 2 1536.7395 1.05 102712 15959 3 1536.740841 513.2538 Myosin-10 OS=Homo sapiens OX=9606 GN=MYH10 PE=1 SV=3 6.74 2731.5 - 1.08E+06 - - - 0.8733 - 3.295 0.589 - 460.5 1 2 1 0.0013 13 0 0 0 4.76E+07 4.52E+07 - - - 8.3394 1 221125_WJC_METTL3_EV_vs_WT_F07.15960.15960.3 1.20E-13 26/80 R.C[160.03]MLQDREDQSILC[160.03]TGESGAGK.T "sp|P35580|MYH10_HUMAN,tr|E7ERA5|E7ERA5_HUMAN" 2 2354.0301 0.71 102713 15960 3 2354.031237 785.684 Myosin-10 OS=Homo sapiens OX=9606 GN=MYH10 PE=1 SV=3 4.32 2731.7 - 801874 - - - 0.4915 - 4.736 0.762 - 1086.2 1 2 1 0.0012 21 0 0 0 8.08E+06 1.14E+07 - - - 10.7637 0.9999 221125_WJC_METTL3_EV_vs_WT_F07.15961.15961.3 2.61E-08 13/52 K.SFFDNISC[160.03]DDNR[166.11]ER[166.11].R "sp|Q8ND56|LS14A_HUMAN,tr|A0A096LP11|A0A096LP11_HUMAN,tr|A0A140TA76|A0A140TA76_HUMAN,tr|A0A0G2JQ95|A0A0G2JQ95_HUMAN" 4 1793.7542 1.2 102714 15961 3 1793.757214 598.9253 Protein LSM14 homolog A OS=Homo sapiens OX=9606 GN=LSM14A PE=1 SV=3 4.23 2731.8 - 523387 - - - 1.6797 - 2.628 0.603 - 181.1 1 2 1 0.003 14 0 0 0 7.58E+06 6.30E+06 - - - 7.8298 0.9891 221125_WJC_METTL3_EV_vs_WT_F07.15967.15967.4 8.26E-10 22/126 A.FASSLVSGLNSSASEPAK[136.11]EPAK[136.11].K "sp|Q86U44|MTA70_HUMAN,tr|F5H6D8|F5H6D8_HUMAN,tr|H0YFV6|H0YFV6_HUMAN,tr|B4DTN4|B4DTN4_HUMAN" 4 2192.1296 0.02 102718 15967 4 2192.1309 549.0397 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 6.14 2732.6 - 2.16E+06 - - - 0.6031 - 3.981 0.529 - 347 1 1 1 0.0013 22 0 0 0 4.36E+05 2.21E+07 - - - 4.2821 0.9998 221125_WJC_METTL3_EV_vs_WT_F07.15969.15969.3 9.09E-05 15/56 R.NPNKLDINTLTGEER.V sp|Q9P2D1|CHD7_HUMAN 1 1712.8693 1.8 102720 15969 3 1712.870518 571.9637 Chromodomain-helicase-DNA-binding protein 7 OS=Homo sapiens OX=9606 GN=CHD7 PE=1 SV=3 4.68 2732.7 - 1.26E+06 - - - 0.6953 - 2.63 0.447 - 256.8 1 2 1 0.0012 15 0 0 0 2.46E+07 1.37E+07 - - - 6.0465 0.9997 221125_WJC_METTL3_EV_vs_WT_F07.15971.15971.4 0.00106 16/72 K.DKADFC[160.03]IIHYAGK.V "sp|P35580|MYH10_HUMAN,sp|P35579|MYH9_HUMAN" 2 1536.7395 0.87 102722 15971 4 1536.741312 385.1922 Myosin-10 OS=Homo sapiens OX=9606 GN=MYH10 PE=1 SV=3 6.74 2733 - 927942 - - - 1.1798 - 2.521 0.437 - 190.5 1 2 1 0.0018 13 0 0 0 1.94E+07 2.23E+07 - - - 3.372 0.9999 221125_WJC_METTL3_EV_vs_WT_F07.15973.15973.3 0.000114 13/40 R.K[136.11]LDPELHLDIK[136.11].V "sp|Q12905|ILF2_HUMAN,tr|B4DY09|B4DY09_HUMAN" 2 1335.7733 0.18 102724 15973 3 1335.774276 446.265 Interleukin enhancer-binding factor 2 OS=Homo sapiens OX=9606 GN=ILF2 PE=1 SV=2 5.38 2733.2 - 570627 - - - 0.7292 - 2.363 0.438 - 184.6 1 2 0 0.001 11 0 0 0 8.36E+06 4.57E+07 - - - 5.8659 0.9996 221125_WJC_METTL3_EV_vs_WT_F07.15974.15974.4 0.000363 19/96 R.LLASTLVHSVKKEQEFR.S "sp|Q9NYF8|BCLF1_HUMAN,tr|E9PKI6|E9PKI6_HUMAN,tr|A0A1W2PQ43|A0A1W2PQ43_HUMAN,tr|E9PK91|E9PK91_HUMAN,tr|E9PJA7|E9PJA7_HUMAN,tr|E9PK09|E9PK09_HUMAN,tr|E9PQN2|E9PQN2_HUMAN" 7 1984.1106 1.8 102725 15974 4 1984.114833 497.0349 Bcl-2-associated transcription factor 1 OS=Homo sapiens OX=9606 GN=BCLAF1 PE=1 SV=2 8.6 2733.3 - 438183 - - - 2.1531 - 3.483 0.456 - 289 1 2 1 0.0043 17 0 0 0 9.83E+06 5.47E+06 - - - 3.6271 1 221125_WJC_METTL3_EV_vs_WT_F07.15975.15975.3 2.82E-09 21/96 K.TPVVQNAASIVQPSPAHVGQQGLSK.L "sp|Q8WXI9|P66B_HUMAN,tr|A0A0U1RRM1|A0A0U1RRM1_HUMAN" 2 2512.3398 2.02 102726 15975 3 2512.338457 838.4539 Transcriptional repressor p66-beta OS=Homo sapiens OX=9606 GN=GATAD2B PE=1 SV=1 8.44 2733.5 - 378626 - - - -0.5286 - 4.214 0.641 - 228.5 1 2 0 -0.0013 25 0 0 0 1.54E+08 7.59E+07 - - - 8.9954 0.8983 221125_WJC_METTL3_EV_vs_WT_F07.15977.15977.4 0.037 Aug-72 R.INFDKYHPGYFGK.V "sp|P46776|RL27A_HUMAN,tr|E9PLL6|E9PLL6_HUMAN" 2 1584.7725 0.57 102728 15977 4 1584.775631 397.2004 60S ribosomal protein L27a OS=Homo sapiens OX=9606 GN=RPL27A PE=1 SV=2 8.44 2733.7 - 259547 - - - 1.9668 - 1.544 0.181 - 25.7 1 2 1 0.0031 13 0 0 0 2.10E+06 3.72E+06 - - - 0.9616 1 221125_WJC_METTL3_EV_vs_WT_F07.15978.15978.2 2.89E-09 18/36 R.QTSGGPVDASSEYQQELER[166.11].E "sp|P18859|ATP5J_HUMAN,tr|A8MUH2|A8MUH2_HUMAN" 2 2089.9428 1.8 102729 15978 2 2089.949629 1045.9787 "ATP synthase-coupling factor 6, mitochondrial OS=Homo sapiens OX=9606 GN=ATP5PF PE=1 SV=1" 4 2733.9 - 238612 - - - 3.279 - 3.501 0.689 - 989.2 1 2 0 0.0069 19 0 0 0 1.85E+07 1.03E+07 - - - 7.2085 0.7678 221125_WJC_METTL3_EV_vs_WT_F07.15982.15982.4 0.112 12/108 K.FNPDEDKQNLFVAGMSDKK.L "sp|O60508|PRP17_HUMAN,tr|Q5SRN1|Q5SRN1_HUMAN" 2 2182.0365 0.72 102731 15982 4 2182.043046 546.5164 Pre-mRNA-processing factor 17 OS=Homo sapiens OX=9606 GN=CDC40 PE=1 SV=1 4.68 2734.4 - 827988 - - - 3.0142 - 2.023 0.162 - 112.8 1 2 1 0.0066 19 0 0 0 4.69E+06 6.52E+06 - - - 0.8726 0.9998 221125_WJC_METTL3_EV_vs_WT_F07.15984.15984.3 1.79E-05 19/48 R.LNKDNDTLKDLLK.A sp|Q9H8Y8|GORS2_HUMAN 1 1528.8461 1.65 102733 15984 3 1528.85017 510.6226 Golgi reassembly-stacking protein 2 OS=Homo sapiens OX=9606 GN=GORASP2 PE=1 SV=3 6.04 2734.6 - 681624 - - - 2.6798 - 3.695 0.5 - 358.8 1 2 2 0.0041 13 0 0 0 1.35E+07 8.16E+06 - - - 7.657 1 221125_WJC_METTL3_EV_vs_WT_F07.15985.15985.2 4.86E-10 18/36 R.QTSGGPVDASSEYQQELER.E "sp|P18859|ATP5J_HUMAN,tr|A8MUH2|A8MUH2_HUMAN" 2 2079.9345 1.8 102734 15985 2 2079.941821 1040.9745 "ATP synthase-coupling factor 6, mitochondrial OS=Homo sapiens OX=9606 GN=ATP5PF PE=1 SV=1" 4 2734.8 - 606878 - - - 3.5169 - 3.59 0.684 - 1011.4 1 2 0 0.0073 19 0 0 0 1.85E+07 1.03E+07 - - - 7.2331 1 221125_WJC_METTL3_EV_vs_WT_F07.15986.15986.3 3.52E-08 17/40 R.KLDPELHLDIK.V "sp|Q12905|ILF2_HUMAN,tr|B4DY09|B4DY09_HUMAN" 2 1319.7449 0.33 102735 15986 3 1319.746591 440.9222 Interleukin enhancer-binding factor 2 OS=Homo sapiens OX=9606 GN=ILF2 PE=1 SV=2 5.38 2734.9 - 519884 - - - 1.2798 - 2.84 0.528 - 390.8 1 2 0 0.0017 11 0 0 0 8.25E+06 2.48E+07 - - - 7.3915 0.998 221125_WJC_METTL3_EV_vs_WT_F07.15987.15987.4 0.00171 Dec-90 K.QR[166.11]FDHIFYTGNTAVGK[136.11].L "sp|P51648|AL3A2_HUMAN,tr|I3L1M4|I3L1M4_HUMAN,tr|A0A5F9ZHI5|A0A5F9ZHI5_HUMAN,tr|A0A5F9ZI12|A0A5F9ZI12_HUMAN,tr|A0A5F9ZHZ9|A0A5F9ZHZ9_HUMAN,tr|A0A5F9ZHN9|A0A5F9ZHN9_HUMAN,tr|A0A5F9ZGX4|A0A5F9ZGX4_HUMAN,tr|J3QRD1|J3QRD1_HUMAN" 8 1870.9445 1.32 102736 15987 4 1870.944316 468.7434 Aldehyde dehydrogenase family 3 member A2 OS=Homo sapiens OX=9606 GN=ALDH3A2 PE=1 SV=1 8.6 2735 - 244951 - - - -0.0989 - 2.299 0.327 - 140.5 1 2 1 -0.0002 16 0 0 0 1.99E+06 1.51E+06 - - - 2.3654 1 221125_WJC_METTL3_EV_vs_WT_F07.15990.15990.3 2.45E-08 16/68 K.YVHYEIDAC[160.03]MDSEAPGSK[136.11].D "sp|Q86U44|MTA70_HUMAN,tr|H0YFV6|H0YFV6_HUMAN" 2 2078.8805 0.02 102737 15990 3 2079.872827 693.9674 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 4.31 2735.4 - 4.75E+06 - - - 477.3411 - 3.193 0.676 - 283.5 1 2 0 0.9923 18 0 0 0 2.83E+06 1.59E+08 - - - 8.6928 1 221125_WJC_METTL3_EV_vs_WT_F07.15993.15993.3 3.21E-10 26/96 K.TPVVQNAASIVQPSPAHVGQQGLSK[136.11].L "sp|Q8WXI9|P66B_HUMAN,tr|A0A0U1RRM1|A0A0U1RRM1_HUMAN" 2 2520.354 2.02 102740 15993 3 2520.357148 841.1253 Transcriptional repressor p66-beta OS=Homo sapiens OX=9606 GN=GATAD2B PE=1 SV=1 8.44 2735.8 - 745603 - - - 1.255 - 4.63 0.657 - 575.1 1 2 0 0.0032 25 0 0 0 1.54E+08 7.59E+07 - - - 9.3899 0.9994 221125_WJC_METTL3_EV_vs_WT_F07.15994.15994.4 0.00819 11/138 R.MTATGSGENSTVAEHLIAQHSAIK[136.11].M "sp|Q7L5N1|CSN6_HUMAN,tr|H7C3T0|H7C3T0_HUMAN,tr|E7EM64|E7EM64_HUMAN" 3 2460.2158 1.33 102741 15994 4 2460.209677 616.0612 COP9 signalosome complex subunit 6 OS=Homo sapiens OX=9606 GN=COPS6 PE=1 SV=1 5.96 2735.9 - 658853 - - - -2.5038 - 2.154 0.363 - 24.6 1 2 0 -0.0062 24 0 0 0 1.88E+07 1.41E+07 - - - 2.6301 1 221125_WJC_METTL3_EV_vs_WT_F07.15995.15995.2 1.08E-09 14/28 K.SSDTNIFDSNVPSNK.S "sp|Q6PJT7|ZC3HE_HUMAN,tr|G3V3Y4|G3V3Y4_HUMAN,tr|G3V473|G3V473_HUMAN,tr|G3V256|G3V256_HUMAN,tr|G3V572|G3V572_HUMAN,tr|G3V3R9|G3V3R9_HUMAN,tr|G3V240|G3V240_HUMAN,tr|A0A3B3IT62|A0A3B3IT62_HUMAN" 8 1623.7376 0.68 102742 15995 2 1623.737091 812.8761 Zinc finger CCCH domain-containing protein 14 OS=Homo sapiens OX=9606 GN=ZC3H14 PE=1 SV=1 4.21 2736 - 569200 - - - -0.3406 - 3.035 0.663 - 348.2 1 2 0 -0.0006 15 0 0 0 1.55E+07 2.27E+07 - - - 6.6673 1 221125_WJC_METTL3_EV_vs_WT_F07.16001.16001.4 1.28E-09 18/138 R.MTATGSGENSTVAEHLIAQHSAIK.M "sp|Q7L5N1|CSN6_HUMAN,tr|H7C3T0|H7C3T0_HUMAN,tr|E7EM64|E7EM64_HUMAN" 3 2452.2016 1.16 102746 16001 4 2452.202538 614.0577 COP9 signalosome complex subunit 6 OS=Homo sapiens OX=9606 GN=COPS6 PE=1 SV=1 5.96 2736.7 - 705933 - - - 0.3674 - 3.471 0.581 - 245.2 1 2 0 0.0009 24 0 0 0 1.61E+07 1.39E+07 - - - 4.6822 1 221125_WJC_METTL3_EV_vs_WT_F07.16004.16004.2 2.80E-07 28-Dec K.SSDTNIFDSNVPSNK[136.11].S "sp|Q6PJT7|ZC3HE_HUMAN,tr|G3V3Y4|G3V3Y4_HUMAN,tr|G3V473|G3V473_HUMAN,tr|G3V256|G3V256_HUMAN,tr|G3V572|G3V572_HUMAN,tr|G3V3R9|G3V3R9_HUMAN,tr|G3V240|G3V240_HUMAN,tr|A0A3B3IT62|A0A3B3IT62_HUMAN" 8 1631.7518 0.55 102749 16004 2 1631.751222 816.8832 Zinc finger CCCH domain-containing protein 14 OS=Homo sapiens OX=9606 GN=ZC3H14 PE=1 SV=1 4.21 2737 - 574171 - - - -0.3812 - 2.697 0.585 - 277.2 1 2 0 -0.0006 15 0 0 0 2.33E+07 4.23E+07 - - - 5.8008 0.9999 221125_WJC_METTL3_EV_vs_WT_F07.16007.16007.4 0.000883 Dec-78 K.RSELPIAELTGHTR.T "sp|Q9H7D7|WDR26_HUMAN,tr|A0A7P0SXD0|A0A7P0SXD0_HUMAN,tr|H0Y9R3|H0Y9R3_HUMAN,tr|A0A7I2YQL3|A0A7I2YQL3_HUMAN,tr|A0A499FIZ0|A0A499FIZ0_HUMAN" 5 1578.8478 0.95 102752 16007 4 1578.848175 395.7192 WD repeat-containing protein 26 OS=Homo sapiens OX=9606 GN=WDR26 PE=1 SV=3 6.76 2737.4 - 162143 - - - 0.235 - 2.134 0.417 - 150.7 1 2 0 0.0004 14 0 0 0 4.45E+06 4.68E+06 - - - 3.1313 1 221125_WJC_METTL3_EV_vs_WT_F07.16011.16011.4 1.37E-07 19/108 R.SFFHQHYLGGQEPTPSNIR.M "sp|P46379|BAG6_HUMAN,tr|A0A7I2V508|A0A7I2V508_HUMAN,tr|A0A7P0MQS5|A0A7P0MQS5_HUMAN,tr|A0A0G2JL47|A0A0G2JL47_HUMAN,tr|A0A024RCR6|A0A024RCR6_HUMAN,tr|A0A0G2JK23|A0A0G2JK23_HUMAN" 6 2214.0606 1.76 102754 16011 4 2214.060455 554.5224 Large proline-rich protein BAG6 OS=Homo sapiens OX=9606 GN=BAG6 PE=1 SV=2 6.66 2737.9 - 1.06E+06 - - - -0.0881 - 3.142 0.511 - 249.8 1 2 0 -0.0002 19 0 0 0 7.40E+07 4.20E+07 - - - 4.061 0.9966 221125_WJC_METTL3_EV_vs_WT_F07.16012.16012.3 1.69E-05 14/60 L.QDDAHPTLVTYADHSK[136.11].L "sp|Q86U44|MTA70_HUMAN,tr|F5H6D8|F5H6D8_HUMAN,tr|H0YFV6|H0YFV6_HUMAN,tr|B4DTN4|B4DTN4_HUMAN" 4 1804.8471 0.12 102755 16012 3 1804.848397 602.623 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 5.13 2737.9 - 803946 - - - 0.6953 - 2.503 0.494 - 241.8 1 1 0 0.0013 16 0 0 0 1.70E+06 1.48E+07 - - - 6.4014 1 221125_WJC_METTL3_EV_vs_WT_F07.16013.16013.3 6.95E-11 24/72 R.SFFHQHYLGGQEPTPSNIR.M "sp|P46379|BAG6_HUMAN,tr|A0A7I2V508|A0A7I2V508_HUMAN,tr|A0A7P0MQS5|A0A7P0MQS5_HUMAN,tr|A0A0G2JL47|A0A0G2JL47_HUMAN,tr|A0A024RCR6|A0A024RCR6_HUMAN,tr|A0A0G2JK23|A0A0G2JK23_HUMAN" 6 2214.0606 1.49 102756 16013 3 2214.051617 739.0275 Large proline-rich protein BAG6 OS=Homo sapiens OX=9606 GN=BAG6 PE=1 SV=2 6.66 2738.1 - 587543 - - - -4.0798 - 3.971 0.681 - 622.7 1 2 0 -0.009 19 0 0 0 4.14E+07 2.78E+07 - - - 9.5179 1 221125_WJC_METTL3_EV_vs_WT_F07.16023.16023.4 1.32E-09 24/144 K.TPVVQNAASIVQPSPAHVGQQGLSK.L "sp|Q8WXI9|P66B_HUMAN,tr|A0A0U1RRM1|A0A0U1RRM1_HUMAN" 2 2512.3398 2.14 102764 16023 4 2512.341649 629.0922 Transcriptional repressor p66-beta OS=Homo sapiens OX=9606 GN=GATAD2B PE=1 SV=1 8.44 2739.4 - 440379 - - - 0.7419 - 4.728 0.524 - 339 1 2 0 0.0019 25 0 0 0 1.51E+07 7.08E+06 - - - 4.2806 0.997 221125_WJC_METTL3_EV_vs_WT_F07.16025.16025.4 0.0149 14/102 K.STTWLHPVTGEAVVTGHR[166.11].R sp|Q9HAU0|PKHA5_HUMAN 1 1957.0045 3.08 102766 16025 4 1957.005974 490.2584 Pleckstrin homology domain-containing family A member 5 OS=Homo sapiens OX=9606 GN=PLEKHA5 PE=1 SV=1 6.66 2739.6 - 310668 - - - 0.7384 - 2.278 0.241 - 130.5 1 2 0 0.0014 18 0 0 0 1.52E+07 4.94E+06 - - - 1.6053 0.9998 221125_WJC_METTL3_EV_vs_WT_F07.16028.16028.2 9.97E-07 20-Oct R.TNAENEFVTIK.K sp|P04264|K2C1_HUMAN 1 1264.6299 51.95 102767 16028 2 1264.631958 633.3222 "Keratin, type II cytoskeletal 1 OS=Homo sapiens OX=9606 GN=KRT1 PE=1 SV=6" 4.53 2740 - 1.04E+06 - - - 1.602 - 2.231 0.59 - 417.1 1 2 0 0.002 11 0 0 0 2.48E+07 4.78E+05 - - - 5.5689 0.9999 221125_WJC_METTL3_EV_vs_WT_F07.16030.16030.4 0.000467 15/144 R.LK[136.11]PSASFGSPVQSEALAPDSMSHPR[166.11].S "sp|Q6BDS2|URFB1_HUMAN,tr|H7C1J4|H7C1J4_HUMAN" 2 2613.2976 1.2 102769 16030 4 2613.297181 654.3317 UHRF1-binding protein 1 OS=Homo sapiens OX=9606 GN=UHRF1BP1 PE=1 SV=1 6.75 2740.3 - 544098 - - - -0.1626 - 2.714 0.427 - 100.6 1 2 0 -0.0004 25 0 0 0 3.98E+06 3.31E+06 - - - 3.2601 1 221125_WJC_METTL3_EV_vs_WT_F07.16032.16032.3 6.14E-06 17/100 R.LGVPC[160.03]GEPAELGGDASEEDHPQVC[160.03]AK[136.11].C "tr|A0A087X1T9|A0A087X1T9_HUMAN,tr|F5H433|F5H433_HUMAN,tr|E7EW59|E7EW59_HUMAN" 3 2729.2152 1.77 102771 16032 3 2729.211208 910.7457 Sal-like protein 2 OS=Homo sapiens OX=9606 GN=SALL2 PE=1 SV=1 4.08 2740.6 - 351325 - - - -1.4792 - 2.401 0.554 - 179.1 1 2 0 -0.004 26 0 0 0 3.58E+07 2.03E+07 - - - 6.7305 0.9986 221125_WJC_METTL3_EV_vs_WT_F07.16037.16037.3 0.000409 22/72 R.SFFHQHYLGGQEPTPSNIR[166.11].M "sp|P46379|BAG6_HUMAN,tr|A0A7I2V508|A0A7I2V508_HUMAN,tr|A0A7P0MQS5|A0A7P0MQS5_HUMAN,tr|A0A0G2JL47|A0A0G2JL47_HUMAN,tr|A0A024RCR6|A0A024RCR6_HUMAN,tr|A0A0G2JK23|A0A0G2JK23_HUMAN" 6 2224.0689 1.53 102774 16037 3 2225.077435 742.3636 Large proline-rich protein BAG6 OS=Homo sapiens OX=9606 GN=BAG6 PE=1 SV=2 6.66 2741.1 - 1.04E+06 - - - 453.4549 - 3.537 0.506 - 414.5 1 2 0 1.0085 19 0 0 0 4.30E+07 2.80E+07 - - - 7.0057 0.9973 221125_WJC_METTL3_EV_vs_WT_F07.16039.16039.3 1.62E-07 17/64 L.LQDDAHPTLVTYADHSK[136.11].L "sp|Q86U44|MTA70_HUMAN,tr|F5H6D8|F5H6D8_HUMAN,tr|H0YFV6|H0YFV6_HUMAN,tr|B4DTN4|B4DTN4_HUMAN" 4 1917.9312 0.01 102776 16039 3 1917.92993 640.3177 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 5.13 2741.3 - 1.84E+06 - - - -0.6653 - 2.991 0.485 - 346.8 1 1 0 -0.0013 17 0 0 0 1.94E+05 2.47E+07 - - - 6.7148 1 221125_WJC_METTL3_EV_vs_WT_F07.16040.16040.3 2.25E-06 20/64 K.ANELPQPPVPEPANAGK.R "sp|P78347|GTF2I_HUMAN,tr|A0A494C1K3|A0A494C1K3_HUMAN" 2 1727.8842 2.37 102777 16040 3 1727.884711 576.9687 General transcription factor II-I OS=Homo sapiens OX=9606 GN=GTF2I PE=1 SV=2 4.53 2741.4 - 1.20E+06 - - - 0.2674 - 3.052 0.515 - 349 1 2 0 0.0005 17 0 0 0 3.35E+07 1.41E+07 - - - 7.1005 1 221125_WJC_METTL3_EV_vs_WT_F07.16042.16042.3 3.80E-07 17/56 K.KVPQVSTPTLVEVSR.N "sp|P02768|ALBU_HUMAN,tr|A0A087WWT3|A0A087WWT3_HUMAN,tr|B7WNR0|B7WNR0_HUMAN,tr|H0YA55|H0YA55_HUMAN,tr|A0A0C4DGB6|A0A0C4DGB6_HUMAN,tr|D6RHD5|D6RHD5_HUMAN,tr|C9JKR2|C9JKR2_HUMAN" 7 1638.9305 999 102779 16042 3 1638.931668 547.3174 Albumin OS=Homo sapiens OX=9606 GN=ALB PE=1 SV=2 8.75 2741.7 - 555627 - - - 0.7304 - 3.209 0.558 - 402.1 1 2 0 0.0012 15 0 0 0 1.63E+07 0.00E+00 - - - 7.8032 0.9999 221125_WJC_METTL3_EV_vs_WT_F07.16047.16047.2 1.93E-07 15/32 K.ANELPQPPVPEPANAGK.R "sp|P78347|GTF2I_HUMAN,tr|A0A494C1K3|A0A494C1K3_HUMAN" 2 1727.8842 1.96 102783 16047 2 1727.886132 864.9494 General transcription factor II-I OS=Homo sapiens OX=9606 GN=GTF2I PE=1 SV=2 4.53 2742.3 - 1.01E+06 - - - 1.0898 - 2.51 0.593 - 527.1 1 2 0 0.0019 17 0 0 0 6.07E+07 3.09E+07 - - - 5.6829 1 221125_WJC_METTL3_EV_vs_WT_F07.16048.16048.3 4.09E-12 24/100 R.LGVPC[160.03]GEPAELGGDASEEDHPQVC[160.03]AK.C "tr|A0A087X1T9|A0A087X1T9_HUMAN,tr|F5H433|F5H433_HUMAN,tr|E7EW59|E7EW59_HUMAN" 3 2721.201 1.77 102784 16048 3 2721.201834 908.0743 Sal-like protein 2 OS=Homo sapiens OX=9606 GN=SALL2 PE=1 SV=1 4.08 2742.4 - 1.06E+06 - - - 0.2899 - 3.389 0.717 - 348.5 1 2 0 0.0008 26 0 0 0 3.58E+07 2.03E+07 - - - 9.3416 0.9998 221125_WJC_METTL3_EV_vs_WT_F07.16050.16050.4 0.000486 15/84 K.VKELVEFAQDDDRLR.E sp|Q14677|EPN4_HUMAN 1 1831.9428 1.28 102786 16050 4 1831.94193 458.993 Clathrin interactor 1 OS=Homo sapiens OX=9606 GN=CLINT1 PE=1 SV=1 4.44 2742.7 - 640973 - - - -0.4896 - 2.628 0.454 - 291.2 1 2 2 -0.0009 15 0 0 0 2.91E+07 2.27E+07 - - - 3.5231 0.9996 221125_WJC_METTL3_EV_vs_WT_F07.16054.16054.3 0.145 17/40 R.R[166.11]K[136.11]QDSGHLDLR[166.11].N "sp|Q86U44|MTA70_HUMAN,tr|B4E349|B4E349_HUMAN,tr|F5H6D8|F5H6D8_HUMAN,tr|B4DTN4|B4DTN4_HUMAN" 4 1351.7315 0 102788 16054 3 1351.732252 451.5844 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 8.75 2743.2 - 535885 - - - 0.5667 - 2.716 0.352 - 412.3 1 2 1 0.0008 11 0 0 0 4.09E+04 1.26E+07 - - - 5.3027 0.9997 221125_WJC_METTL3_EV_vs_WT_F07.16057.16057.3 2.77E-08 19/56 K.VKELVEFAQDDDRLR.E sp|Q14677|EPN4_HUMAN 1 1831.9428 1.15 102791 16057 3 1831.948861 611.6549 Clathrin interactor 1 OS=Homo sapiens OX=9606 GN=CLINT1 PE=1 SV=1 4.44 2743.6 - 754825 - - - 3.2938 - 3.416 0.547 - 409.3 1 2 2 0.006 15 0 0 0 2.29E+07 2.00E+07 - - - 7.8424 0.9998 221125_WJC_METTL3_EV_vs_WT_F07.16058.16058.4 5.97E-07 14/78 K.AKAPIQDIWYHEDR.L "sp|Q9Y3D9|RT23_HUMAN,tr|J3QLR8|J3QLR8_HUMAN" 2 1740.8584 1.39 102792 16058 4 1740.857511 436.2219 "28S ribosomal protein S23, mitochondrial OS=Homo sapiens OX=9606 GN=MRPS23 PE=1 SV=2" 5.38 2743.7 - 627803 - - - -0.4929 - 2.295 0.495 - 105.5 1 2 1 -0.0009 14 0 0 0 3.23E+07 2.33E+07 - - - 3.8366 0.9998 221125_WJC_METTL3_EV_vs_WT_F07.16059.16059.4 2.87E-07 Dec-78 K.AK[136.11]APIQDIWYHEDR[166.11].L "sp|Q9Y3D9|RT23_HUMAN,tr|J3QLR8|J3QLR8_HUMAN" 2 1758.8808 1.39 102793 16059 4 1758.878795 440.7275 "28S ribosomal protein S23, mitochondrial OS=Homo sapiens OX=9606 GN=MRPS23 PE=1 SV=2" 5.38 2743.9 - 494853 - - - -1.1621 - 2.614 0.489 - 148.7 1 2 1 -0.002 14 0 0 0 3.23E+07 2.33E+07 - - - 3.8314 0.9999 221125_WJC_METTL3_EV_vs_WT_F07.16060.16060.3 6.73E-09 14/52 K.AK[136.11]APIQDIWYHEDR[166.11].L "sp|Q9Y3D9|RT23_HUMAN,tr|J3QLR8|J3QLR8_HUMAN" 2 1758.8808 1.31 102794 16060 3 1758.87934 587.3009 "28S ribosomal protein S23, mitochondrial OS=Homo sapiens OX=9606 GN=MRPS23 PE=1 SV=2" 5.38 2744 - 446370 - - - -0.8522 - 2.928 0.565 - 182.5 1 2 1 -0.0015 14 0 0 0 3.04E+07 2.32E+07 - - - 7.6938 1 221125_WJC_METTL3_EV_vs_WT_F07.16061.16061.4 4.65E-06 15/96 K.GYPHLC[160.03]SIC[160.03]DLPVHSNK.E "sp|P43243|MATR3_HUMAN,tr|A8MXP9|A8MXP9_HUMAN,tr|D6R991|D6R991_HUMAN,tr|A0A0R4J2E8|A0A0R4J2E8_HUMAN,tr|H0Y8T4|H0Y8T4_HUMAN,tr|D6REM6|D6REM6_HUMAN" 6 1995.9295 1.35 102795 16061 4 1995.92767 499.9897 Matrin-3 OS=Homo sapiens OX=9606 GN=MATR3 PE=1 SV=2 6.9 2744.1 - 427512 - - - -0.9179 - 2.202 0.553 - 114.7 1 2 0 -0.0018 17 0 0 0 9.22E+08 6.82E+08 - - - 4.3129 0.9999 221125_WJC_METTL3_EV_vs_WT_F07.16066.16066.3 1.03E-07 14/52 K.AKAPIQDIWYHEDR.L "sp|Q9Y3D9|RT23_HUMAN,tr|J3QLR8|J3QLR8_HUMAN" 2 1740.8584 1.1 102798 16066 3 1740.859403 581.2934 "28S ribosomal protein S23, mitochondrial OS=Homo sapiens OX=9606 GN=MRPS23 PE=1 SV=2" 5.38 2744.8 - 729599 - - - 0.594 - 3.003 0.595 - 234.6 1 2 1 0.001 14 0 0 0 3.06E+07 2.79E+07 - - - 8.0956 1 221125_WJC_METTL3_EV_vs_WT_F07.16067.16067.3 3.30E-09 19/72 R.GLLQDDAHPTLVTYADHSK[136.11].L "sp|Q86U44|MTA70_HUMAN,tr|F5H6D8|F5H6D8_HUMAN,tr|H0YFV6|H0YFV6_HUMAN,tr|B4DTN4|B4DTN4_HUMAN" 4 2088.0367 0 102799 16067 3 2088.036688 697.0195 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 5.13 2744.8 - 7.77E+06 - - - -0.0216 - 3.329 0.62 - 451.7 1 2 0 0 19 0 0 0 8.30E+05 4.83E+08 - - - 8.4071 1 221125_WJC_METTL3_EV_vs_WT_F07.16073.16073.2 2.41E-08 Oct-36 K.TTMESISNTSTQSLTAETK.D "sp|P82094|TMF1_HUMAN,tr|F8WF45|F8WF45_HUMAN,tr|A0A2R8Y7M0|A0A2R8Y7M0_HUMAN" 3 2028.9521 1.71 102805 16073 2 2028.955601 1015.4833 TATA element modulatory factor OS=Homo sapiens OX=9606 GN=TMF1 PE=1 SV=2 4.53 2745.5 - 199597 - - - 1.7107 - 2.716 0.661 - 188.9 1 2 0 0.0035 19 0 0 0 7.83E+06 4.58E+06 - - - 6.3785 0.9998 221125_WJC_METTL3_EV_vs_WT_F07.16080.16080.4 1.50E-05 15/84 K.VK[136.11]ELVEFAQDDDR[166.11]LR[166.11].E sp|Q14677|EPN4_HUMAN 1 1859.9736 1.27 102810 16080 4 1859.974371 466.0007 Clathrin interactor 1 OS=Homo sapiens OX=9606 GN=CLINT1 PE=1 SV=1 4.44 2746.3 - 1.29E+06 - - - 0.4323 - 2.856 0.462 - 288.2 1 2 2 0.0008 15 0 0 0 2.91E+07 2.30E+07 - - - 3.6225 1 221125_WJC_METTL3_EV_vs_WT_F07.16085.16085.3 2.35E-09 20/72 K.PSTASAVPELATDPELEK[136.11]K[136.11].L "sp|Q86U44|MTA70_HUMAN,tr|B4E349|B4E349_HUMAN,tr|F5H6D8|F5H6D8_HUMAN,tr|H0YFV6|H0YFV6_HUMAN,tr|B4DTN4|B4DTN4_HUMAN" 5 1998.0492 0.01 102813 16085 3 1998.050162 667.0237 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 4.41 2747 - 1.24E+06 - - - 0.4805 - 3.71 0.667 - 446.1 1 1 0 0.001 19 0 0 0 3.44E+06 2.32E+08 - - - 9.1971 1 221125_WJC_METTL3_EV_vs_WT_F07.16087.16087.3 5.65E-10 17/88 R.QAVINGPNVHPGASMVINEDGSR.T "sp|O95602|RPA1_HUMAN,tr|B9ZVN9|B9ZVN9_HUMAN" 2 2361.1495 1.81 102815 16087 3 2361.147036 788.0571 DNA-directed RNA polymerase I subunit RPA1 OS=Homo sapiens OX=9606 GN=POLR1A PE=1 SV=2 5.32 2747.2 - 463032 - - - -1.0613 - 3.71 0.636 - 208.9 1 2 0 -0.0025 23 0 0 0 6.77E+06 3.73E+06 - - - 8.7057 1 221125_WJC_METTL3_EV_vs_WT_F07.16088.16088.2 3.19E-12 17/36 K.TTMESISNTSTQSLTAETK[136.11].D "sp|P82094|TMF1_HUMAN,tr|F8WF45|F8WF45_HUMAN,tr|A0A2R8Y7M0|A0A2R8Y7M0_HUMAN" 3 2036.9663 1.71 102816 16088 2 2036.964259 1019.4904 TATA element modulatory factor OS=Homo sapiens OX=9606 GN=TMF1 PE=1 SV=2 4.53 2747.4 - 281526 - - - -1.0167 - 3.677 0.695 - 849.1 1 2 0 -0.0021 19 0 0 0 7.83E+06 4.58E+06 - - - 7.3749 0.9998 221125_WJC_METTL3_EV_vs_WT_F07.16090.16090.3 0.000305 Sep-72 K.TTMESISNTSTQSLTAETK.D "sp|P82094|TMF1_HUMAN,tr|F8WF45|F8WF45_HUMAN,tr|A0A2R8Y7M0|A0A2R8Y7M0_HUMAN" 3 2028.9521 1.38 102817 16090 3 2028.955178 677.3247 TATA element modulatory factor OS=Homo sapiens OX=9606 GN=TMF1 PE=1 SV=2 4.53 2747.6 - 901942 - - - 1.5023 - 2.316 0.4 - 83.2 1 2 0 0.003 19 0 0 0 1.70E+07 1.23E+07 - - - 5.0621 0.9417 221125_WJC_METTL3_EV_vs_WT_F07.16092.16092.4 0.0141 7/108 K.FAALDNEEEDKEEEIIKEK.E "sp|Q8NE71|ABCF1_HUMAN,tr|Q5STZ8|Q5STZ8_HUMAN,tr|A0A0G2JJB9|A0A0G2JJB9_HUMAN" 3 2278.0853 0.93 102818 16092 4 2278.089041 570.5286 ATP-binding cassette sub-family F member 1 OS=Homo sapiens OX=9606 GN=ABCF1 PE=1 SV=2 4.1 2747.8 - 673726 - - - 1.6628 - 1.789 0.246 - 26 4 2 2 0.0038 19 0 0 0 2.39E+07 2.57E+07 - - - 1.104 0.9985 221125_WJC_METTL3_EV_vs_WT_F07.16093.16093.4 0.00407 Oct-90 R.LSFPSIKPDTDQTLKK.E "sp|Q92785|REQU_HUMAN,tr|J3KMZ8|J3KMZ8_HUMAN" 2 1816.9935 1.31 102819 16093 4 1816.993449 455.2556 Zinc finger protein ubi-d4 OS=Homo sapiens OX=9606 GN=DPF2 PE=1 SV=2 8.5 2747.9 - 234925 - - - -0.0088 - 1.868 0.281 - 43.3 1 2 0 0 16 0 0 0 3.38E+08 2.57E+08 - - - 1.8919 0.9999 221125_WJC_METTL3_EV_vs_WT_F07.16103.16103.3 5.01E-05 17/52 K.AQIHDLVLVGGSTR[166.11].L "sp|P0DMV8|HS71A_HUMAN,sp|P0DMV9|HS71B_HUMAN,tr|V9GZ37|V9GZ37_HUMAN,tr|A0A0G2JIW1|A0A0G2JIW1_HUMAN" 4 1474.8131 0.37 102827 16103 3 1474.814727 492.6117 Heat shock 70 kDa protein 1A OS=Homo sapiens OX=9606 GN=HSPA1A PE=1 SV=1 6.79 2749.2 - 487804 - - - 1.072 - 2.827 0.396 - 336.7 1 2 0 0.0016 14 0 0 0 2.90E+07 7.88E+07 - - - 5.7163 0.9901 221125_WJC_METTL3_EV_vs_WT_F07.16105.16105.3 0.41 28-Oct R.R[166.11]R[166.11]FEFDFR[166.11].D "sp|Q6Y7W6|GGYF2_HUMAN,tr|A0A7I2V3H7|A0A7I2V3H7_HUMAN,tr|I1E4Y6|I1E4Y6_HUMAN,tr|A0A7I2V516|A0A7I2V516_HUMAN,tr|A0A7I2V3H0|A0A7I2V3H0_HUMAN,tr|C9JHW1|C9JHW1_HUMAN,tr|A0A7I2V361|A0A7I2V361_HUMAN,tr|E7ESB6|E7ESB6_HUMAN" 8 1201.6135 2.75 102829 16105 3 1201.614804 401.5451 GRB10-interacting GYF protein 2 OS=Homo sapiens OX=9606 GN=GIGYF2 PE=1 SV=1 9.51 2749.4 - 156959 - - - 1.0969 - 1.333 0.308 - 194.6 1 2 1 0.0013 8 0 0 0 5.22E+06 1.90E+06 - - - 2.8719 1 221125_WJC_METTL3_EV_vs_WT_F07.16108.16108.3 2.10E-05 14/52 K.RDPTAEQFQEELEK.F sp|P31944|CASPE_HUMAN 1 1718.8111 16.62 102830 16108 3 1718.812793 573.9443 Caspase-14 OS=Homo sapiens OX=9606 GN=CASP14 PE=1 SV=2 4.25 2749.8 - 4.34E+06 - - - 0.9594 - 2.688 0.527 - 345.7 1 2 0 0.0016 14 0 0 0 1.02E+08 6.11E+06 - - - 7.0428 1 221125_WJC_METTL3_EV_vs_WT_F07.16109.16109.3 2.34E-07 14/80 K.ITVPGNFQGHSGAQC[160.03]ITC[160.03]SYK[136.11].A sp|Q08945|SSRP1_HUMAN 1 2332.082 0.81 102831 16109 3 2332.081626 778.3679 FACT complex subunit SSRP1 OS=Homo sapiens OX=9606 GN=SSRP1 PE=1 SV=1 8.05 2750 - 711471 - - - -0.1544 - 2.985 0.624 - 126.4 1 2 0 -0.0004 21 0 0 0 1.74E+07 2.17E+07 - - - 8.1187 0.9997 221125_WJC_METTL3_EV_vs_WT_F07.16110.16110.3 1.69E-05 16/88 R.QAVINGPNVHPGASMVINEDGSR[166.11].T "sp|O95602|RPA1_HUMAN,tr|B9ZVN9|B9ZVN9_HUMAN" 2 2371.1578 1.89 102832 16110 3 2371.147758 791.3932 DNA-directed RNA polymerase I subunit RPA1 OS=Homo sapiens OX=9606 GN=POLR1A PE=1 SV=2 5.32 2750.1 - 516381 - - - -4.2401 - 2.912 0.469 - 212.4 1 2 0 -0.0101 23 0 0 0 6.77E+06 3.58E+06 - - - 6.2735 1 221125_WJC_METTL3_EV_vs_WT_F07.16114.16114.4 5.87E-07 14/96 K.GYPHLC[160.03]SIC[160.03]DLPVHSNK[136.11].E "sp|P43243|MATR3_HUMAN,tr|A8MXP9|A8MXP9_HUMAN,tr|D6R991|D6R991_HUMAN,tr|A0A0R4J2E8|A0A0R4J2E8_HUMAN,tr|H0Y8T4|H0Y8T4_HUMAN,tr|D6REM6|D6REM6_HUMAN" 6 2003.9437 1.35 102834 16114 4 2003.943152 501.9932 Matrin-3 OS=Homo sapiens OX=9606 GN=MATR3 PE=1 SV=2 6.9 2750.6 - 1.14E+06 - - - -0.2745 - 2.395 0.551 - 95.6 1 2 0 -0.0006 17 0 0 0 9.21E+08 6.81E+08 - - - 4.325 1 221125_WJC_METTL3_EV_vs_WT_F07.16115.16115.3 1.63E-08 16/80 K.ITVPGNFQGHSGAQC[160.03]ITC[160.03]SYK.A sp|Q08945|SSRP1_HUMAN 1 2324.0678 0.81 102835 16115 3 2324.070405 775.6965 FACT complex subunit SSRP1 OS=Homo sapiens OX=9606 GN=SSRP1 PE=1 SV=1 8.05 2750.7 - 706175 - - - 1.1269 - 2.67 0.654 - 108.9 1 2 0 0.0026 21 0 0 0 1.74E+07 2.17E+07 - - - 8.1852 0.9914 221125_WJC_METTL3_EV_vs_WT_F07.16123.16123.3 0.00296 16/48 R.EQDLPLAEAVRPK.T sp|Q96A49|SYAP1_HUMAN 1 1464.7936 2.98 102841 16123 3 1464.795918 489.2718 Synapse-associated protein 1 OS=Homo sapiens OX=9606 GN=SYAP1 PE=1 SV=1 4.68 2751.8 - 885824 - - - 1.5531 - 2.165 0.135 - 392.4 1 2 0 0.0023 13 0 0 0 3.38E+07 1.14E+07 - - - 2.1387 0.9999 221125_WJC_METTL3_EV_vs_WT_F07.16124.16124.2 6.22E-08 16/32 K.ANELPQPPVPEPANAGK[136.11].R "sp|P78347|GTF2I_HUMAN,tr|A0A494C1K3|A0A494C1K3_HUMAN" 2 1735.8984 1.96 102842 16124 2 1735.899039 868.9565 General transcription factor II-I OS=Homo sapiens OX=9606 GN=GTF2I PE=1 SV=2 4.53 2751.9 - 791752 - - - 0.3399 - 2.448 0.593 - 565.6 1 2 0 0.0006 17 0 0 0 6.88E+07 3.51E+07 - - - 5.6218 0.9939 221125_WJC_METTL3_EV_vs_WT_F07.16127.16127.2 0.00181 30-Jul K.ETDGSSQIK[136.11]QEPDPTW.- "sp|P78347|GTF2I_HUMAN,tr|A0A494C1K3|A0A494C1K3_HUMAN" 2 1824.8257 1.65 102845 16127 2 1824.828021 913.4201 General transcription factor II-I OS=Homo sapiens OX=9606 GN=GTF2I PE=1 SV=2 3.92 2752.3 - 237084 - - - 1.2511 - 1.533 0.442 - 110.2 1 2 1 0.0023 16 0 0 0 1.98E+07 1.20E+07 - - - 3.3553 0.9994 221125_WJC_METTL3_EV_vs_WT_F07.16128.16128.3 0.0589 Sep-64 R.TTSISAGNEEFQDAIRR.A sp|Q8TAP6|CEP76_HUMAN 1 1893.9181 7.31 102846 16128 3 1893.917519 632.3133 Centrosomal protein of 76 kDa OS=Homo sapiens OX=9606 GN=CEP76 PE=1 SV=1 4.68 2752.4 - 235808 - - - -0.2899 - 1.958 0.314 - 60.9 1 2 0 -0.0006 17 0 0 0 4.08E+06 5.59E+05 - - - 3.7381 1 221125_WJC_METTL3_EV_vs_WT_F07.16130.16130.4 1.52E-06 15/84 R.R[166.11]GEAHLAVNDFELAR[166.11].A sp|Q02790|FKBP4_HUMAN 1 1716.8811 1.22 102848 16130 4 1716.880315 430.2275 Peptidyl-prolyl cis-trans isomerase FKBP4 OS=Homo sapiens OX=9606 GN=FKBP4 PE=1 SV=3 5.45 2752.7 - 138830 - - - -0.4322 - 2.932 0.48 - 221.6 1 2 0 -0.0007 15 0 0 0 7.28E+06 5.95E+06 - - - 3.7886 1 221125_WJC_METTL3_EV_vs_WT_F07.16139.16139.3 6.55E-11 14/72 K.FAALDNEEEDKEEEIIKEK.E "sp|Q8NE71|ABCF1_HUMAN,tr|Q5STZ8|Q5STZ8_HUMAN,tr|A0A0G2JJB9|A0A0G2JJB9_HUMAN" 3 2278.0853 1.25 102854 16139 3 2278.088169 760.369 ATP-binding cassette sub-family F member 1 OS=Homo sapiens OX=9606 GN=ABCF1 PE=1 SV=2 4.1 2753.7 - 453761 - - - 1.28 - 3.147 0.648 - 236.2 1 2 2 0.0029 19 0 0 0 8.09E+06 6.45E+06 - - - 8.5804 1 221125_WJC_METTL3_EV_vs_WT_F07.16141.16141.4 1.47E-07 18/114 R.SFFQDEHVADSENAENR[166.11]PFR[166.11].R "sp|Q5JSZ5|PRC2B_HUMAN,tr|A0A804HKC3|A0A804HKC3_HUMAN" 2 2414.079 1.84 102855 16141 4 2414.080982 604.527 Protein PRRC2B OS=Homo sapiens OX=9606 GN=PRRC2B PE=1 SV=2 4.5 2753.9 - 2.28E+06 - - - 0.804 - 3.079 0.536 - 134.5 1 2 0 0.0019 20 0 0 0 6.05E+07 3.28E+07 - - - 4.2668 0.9942 221125_WJC_METTL3_EV_vs_WT_F07.16145.16145.4 0.000865 15/90 K.FILAPAKQEDEWDKPR.L sp|P13674|P4HA1_HUMAN 1 1941.9949 1.58 102859 16145 4 1942.001995 486.506 Prolyl 4-hydroxylase subunit alpha-1 OS=Homo sapiens OX=9606 GN=P4HA1 PE=1 SV=2 4.78 2754.4 - 633003 - - - 3.673 - 2.023 0.362 - 80.1 1 2 1 0.0071 16 0 0 0 5.95E+06 3.76E+06 - - - 2.6231 0.9995 221125_WJC_METTL3_EV_vs_WT_F07.16146.16146.4 0.00067 13/90 R.LSFPSIK[136.11]PDTDQTLK[136.11]K[136.11].E "sp|Q92785|REQU_HUMAN,tr|J3KMZ8|J3KMZ8_HUMAN" 2 1841.0361 1.06 102860 16146 4 1841.04173 461.2663 Zinc finger protein ubi-d4 OS=Homo sapiens OX=9606 GN=DPF2 PE=1 SV=2 8.5 2754.5 - 585450 - - - 3.0771 - 2.412 0.399 - 80.3 1 2 0 0.0057 16 0 0 0 1.04E+07 9.83E+06 - - - 3.0075 0.9999 221125_WJC_METTL3_EV_vs_WT_F07.16147.16147.3 6.55E-10 19/60 K.ILDSVGIEADDDRLNK.V sp|P05387|RLA2_HUMAN 1 1771.8952 1.41 102861 16147 3 1771.897455 591.639 60S acidic ribosomal protein P2 OS=Homo sapiens OX=9606 GN=RPLP2 PE=1 SV=1 4.04 2754.6 - 521319 - - - 1.2681 - 3.428 0.529 - 424.1 1 2 1 0.0022 16 0 0 0 1.55E+07 1.10E+07 - - - 7.5983 1 221125_WJC_METTL3_EV_vs_WT_F07.16148.16148.3 5.18E-07 21/60 K.R[166.11]NFILDQTNVSAAAQR[166.11].R "sp|Q00839|HNRPU_HUMAN,tr|A0A1W2PQL0|A0A1W2PQL0_HUMAN,tr|A0A1W2PPL4|A0A1W2PPL4_HUMAN,tr|A0A1W2PQ74|A0A1W2PQ74_HUMAN,tr|Q5RI18|Q5RI18_HUMAN,tr|A0A1W2PP35|A0A1W2PP35_HUMAN,tr|A0A1W2PPS1|A0A1W2PPS1_HUMAN,tr|A0A1W2PRZ7|A0A1W2PRZ7_HUMAN,tr|A0A1W2PPH7|A0A1W2PPH7_HUMAN,tr|A0A1W2PQD4|A0A1W2PQD4_HUMAN,tr|A0A1W2PP34|A0A1W2PP34_HUMAN,tr|A0A1X7SBS1|A0A1X7SBS1_HUMAN" 12 1822.9553 1.07 102862 16148 3 1822.95873 608.659 Heterogeneous nuclear ribonucleoprotein U OS=Homo sapiens OX=9606 GN=HNRNPU PE=1 SV=6 9.6 2754.8 - 375813 - - - 1.8903 - 4 0.517 - 645.8 1 2 0 0.0034 16 0 0 0 3.06E+07 2.86E+07 - - - 7.8601 0.999 221125_WJC_METTL3_EV_vs_WT_F07.16149.16149.3 0.00056 Oct-40 R.AVFPSIVGRPR.Q "sp|Q6S8J3|POTEE_HUMAN,sp|P63261|ACTG_HUMAN,sp|P68133|ACTS_HUMAN,sp|P62736|ACTA_HUMAN,sp|Q9BYX7|ACTBM_HUMAN,sp|P68032|ACTC_HUMAN,sp|P60709|ACTB_HUMAN,sp|P63267|ACTH_HUMAN,sp|A5A3E0|POTEF_HUMAN,sp|P0CG38|POTEI_HUMAN,tr|A0A804GS07|A0A804GS07_HUMAN,tr|I3L3I0|I3L3I0_HUMAN,tr|G5E9R0|G5E9R0_HUMAN,tr|E7EVS6|E7EVS6_HUMAN,tr|B8ZZJ2|B8ZZJ2_HUMAN,tr|J3KT65|J3KT65_HUMAN,tr|I3L3R2|I3L3R2_HUMAN,tr|K7EM38|K7EM38_HUMAN,tr|F6QUT6|F6QUT6_HUMAN,tr|C9JTX5|C9JTX5_HUMAN,tr|A0A6Q8PH58|A0A6Q8PH58_HUMAN,tr|F6UVQ4|F6UVQ4_HUMAN,tr|F8WB63|F8WB63_HUMAN,tr|I3L1U9|I3L1U9_HUMAN,tr|A0A2R8Y793|A0A2R8Y793_HUMAN,tr|I3L4N8|I3L4N8_HUMAN,tr|C9JUM1|C9JUM1_HUMAN,tr|F8WCH0|F8WCH0_HUMAN,tr|C9JZR7|C9JZR7_HUMAN,tr|C9JFL5|C9JFL5_HUMAN,tr|A0A2R8YGF8|A0A2R8YGF8_HUMAN,tr|A6NL76|A6NL76_HUMAN" 32 1197.6982 1.34 102863 16149 3 1197.704093 400.24 POTE ankyrin domain family member E OS=Homo sapiens OX=9606 GN=POTEE PE=2 SV=3 12 2754.9 - 324516 - - - 4.8986 - 1.971 0.466 - 156.1 1 2 0 0.0059 11 0 0 0 5.28E+06 3.93E+06 - - - 5.6614 0.8755 221125_WJC_METTL3_EV_vs_WT_F07.16150.16150.4 0.0446 Oct-90 K.VILHLKEDQTEYLEER.R "sp|P08238|HS90B_HUMAN,sp|Q58FF6|H90B4_HUMAN,sp|Q58FF7|H90B3_HUMAN,sp|P07900|HS90A_HUMAN,tr|G3V2J8|G3V2J8_HUMAN" 5 2014.0371 0.7 102864 16150 4 2014.04606 504.5166 Heat shock protein HSP 90-beta OS=Homo sapiens OX=9606 GN=HSP90AB1 PE=1 SV=4 4.57 2755 - 241365 - - - 4.4383 - 1.948 0.235 - 81 1 2 1 0.0089 16 0 0 0 1.22E+07 1.75E+07 - - - 1.5039 1 221125_WJC_METTL3_EV_vs_WT_F07.16155.16155.3 9.37E-07 21/60 K.RNFILDQTNVSAAAQR.R "sp|Q00839|HNRPU_HUMAN,tr|A0A1W2PQL0|A0A1W2PQL0_HUMAN,tr|A0A1W2PPL4|A0A1W2PPL4_HUMAN,tr|A0A1W2PQ74|A0A1W2PQ74_HUMAN,tr|Q5RI18|Q5RI18_HUMAN,tr|A0A1W2PP35|A0A1W2PP35_HUMAN,tr|A0A1W2PPS1|A0A1W2PPS1_HUMAN,tr|A0A1W2PRZ7|A0A1W2PRZ7_HUMAN,tr|A0A1W2PPH7|A0A1W2PPH7_HUMAN,tr|A0A1W2PQD4|A0A1W2PQD4_HUMAN,tr|A0A1W2PP34|A0A1W2PP34_HUMAN,tr|A0A1X7SBS1|A0A1X7SBS1_HUMAN" 12 1802.9387 1.07 102867 16155 3 1802.938986 601.9869 Heterogeneous nuclear ribonucleoprotein U OS=Homo sapiens OX=9606 GN=HNRNPU PE=1 SV=6 9.6 2755.7 - 939938 - - - 0.1342 - 4.159 0.57 - 660.4 1 2 0 0.0002 16 0 0 0 3.06E+07 2.86E+07 - - - 8.5519 0.9989 221125_WJC_METTL3_EV_vs_WT_F07.16159.16159.2 1.49E-07 30-Oct K.ETDGSSQIKQEPDPTW.- "sp|P78347|GTF2I_HUMAN,tr|A0A494C1K3|A0A494C1K3_HUMAN" 2 1816.8115 1.66 102871 16159 2 1816.810744 909.413 General transcription factor II-I OS=Homo sapiens OX=9606 GN=GTF2I PE=1 SV=2 3.92 2756.2 - 276983 - - - -0.437 - 2.142 0.608 - 248.8 1 2 1 -0.0008 16 0 0 0 1.99E+07 1.20E+07 - - - 5.4042 1 221125_WJC_METTL3_EV_vs_WT_F07.16161.16161.4 3.15E-06 20/114 R.SFFQDEHVADSENAENRPFR.R "sp|Q5JSZ5|PRC2B_HUMAN,tr|A0A804HKC3|A0A804HKC3_HUMAN" 2 2394.0625 1.91 102872 16161 4 2394.066338 599.5229 Protein PRRC2B OS=Homo sapiens OX=9606 GN=PRRC2B PE=1 SV=2 4.5 2756.5 - 1.99E+06 - - - 1.6027 - 2.835 0.601 - 192 1 2 0 0.0038 20 0 0 0 6.27E+07 3.28E+07 - - - 4.8044 0.9999 221125_WJC_METTL3_EV_vs_WT_F07.16163.16163.4 4.08E-08 18/84 R.RGEAHLAVNDFELAR.A sp|Q02790|FKBP4_HUMAN 1 1696.8645 1.22 102873 16163 4 1696.868564 425.2234 Peptidyl-prolyl cis-trans isomerase FKBP4 OS=Homo sapiens OX=9606 GN=FKBP4 PE=1 SV=3 5.45 2756.7 - 512010 - - - 2.385 - 3.076 0.51 - 267.6 1 2 0 0.004 15 0 0 0 7.28E+06 5.95E+06 - - - 4.066 1 221125_WJC_METTL3_EV_vs_WT_F07.16167.16167.3 1.35E-12 25/76 R.LAQIHIQQQDQC[160.03]VEITEESK.A "sp|O75935|DCTN3_HUMAN,tr|X6RCK5|X6RCK5_HUMAN" 2 2396.1642 4.99 102877 16167 3 2396.177033 799.7287 Dynactin subunit 3 OS=Homo sapiens OX=9606 GN=DCTN3 PE=1 SV=1 4.4 2757 - 826704 - - - 5.3602 - 4.453 0.693 - 1158.9 1 2 0 0.0128 20 0 0 0 8.53E+06 1.71E+06 - - - 9.8862 0.9994 221125_WJC_METTL3_EV_vs_WT_F07.16171.16171.4 5.05E-06 16/84 K.FK[136.11]VESEQQYFEIEK[136.11]R[166.11].L "sp|P12270|TPR_HUMAN,tr|Q5SWX9|Q5SWX9_HUMAN" 2 1985.0105 3.45 102881 16171 4 1985.015403 497.2599 Nucleoprotein TPR OS=Homo sapiens OX=9606 GN=TPR PE=1 SV=3 4.95 2757.6 - 466300 - - - 2.4892 - 2.66 0.448 - 315.3 1 2 1 0.0049 15 0 0 0 3.92E+07 1.14E+07 - - - 3.4741 0.9982 221125_WJC_METTL3_EV_vs_WT_F07.16172.16172.3 1.23E-06 15/68 R.EKTPLIDLC[160.03]DGQADQAAK.V "sp|Q9NZB2|F120A_HUMAN,tr|A0A0C4DG79|A0A0C4DG79_HUMAN,tr|A0A494C0Y9|A0A494C0Y9_HUMAN" 3 1971.9572 0.91 102882 16172 3 1971.967625 658.3263 Constitutive coactivator of PPAR-gamma-like protein 1 OS=Homo sapiens OX=9606 GN=FAM120A PE=1 SV=2 4.23 2757.7 - 379257 - - - 5.3089 - 2.763 0.543 - 345.3 1 2 1 0.0105 18 0 0 0 2.83E+07 3.10E+07 - - - 7.1217 0.9999 221125_WJC_METTL3_EV_vs_WT_F07.16178.16178.3 0.00011 15/60 K.ILDSVGIEADDDR[166.11]LNK[136.11].V sp|P05387|RLA2_HUMAN 1 1789.9177 1.41 102886 16178 3 1789.91802 597.6465 60S acidic ribosomal protein P2 OS=Homo sapiens OX=9606 GN=RPLP2 PE=1 SV=1 4.04 2758.4 - 1.24E+06 - - - 0.1911 - 2.953 0.524 - 250.3 1 2 1 0.0003 16 0 0 0 1.55E+07 1.10E+07 - - - 7.1604 1 221125_WJC_METTL3_EV_vs_WT_F07.16179.16179.3 4.87E-09 21/76 R.VDASTQKGEESETFDVELTK.N "sp|O75970|MPDZ_HUMAN,tr|F5H1U9|F5H1U9_HUMAN" 2 2212.0383 1.27 102887 16179 3 2212.046446 738.3534 Multiple PDZ domain protein OS=Homo sapiens OX=9606 GN=MPDZ PE=1 SV=2 4.08 2758.5 - 993891 - - - 3.6812 - 4.103 0.642 - 429.2 1 2 1 0.0081 20 0 0 0 1.03E+07 8.12E+06 - - - 9.1203 1 221125_WJC_METTL3_EV_vs_WT_F07.16180.16180.3 1.87E-11 22/56 K.FKVESEQQYFEIEKR.L "sp|P12270|TPR_HUMAN,tr|Q5SWX9|Q5SWX9_HUMAN" 2 1958.9738 4.13 102888 16180 3 1958.974964 653.9985 Nucleoprotein TPR OS=Homo sapiens OX=9606 GN=TPR PE=1 SV=3 4.95 2758.7 - 910229 - - - 0.5983 - 3.914 0.637 - 898.1 1 2 1 0.0012 15 0 0 0 1.85E+07 4.47E+06 - - - 9.2022 1 221125_WJC_METTL3_EV_vs_WT_F07.16182.16182.3 2.85E-10 17/60 K.VILHLK[136.11]EDQTEYLEER[166.11].R "sp|P08238|HS90B_HUMAN,sp|Q58FF6|H90B4_HUMAN,sp|Q58FF7|H90B3_HUMAN,sp|P07900|HS90A_HUMAN,tr|G3V2J8|G3V2J8_HUMAN" 5 2032.0596 0.47 102890 16182 3 2032.062108 678.3605 Heat shock protein HSP 90-beta OS=Homo sapiens OX=9606 GN=HSP90AB1 PE=1 SV=4 4.57 2758.9 - 639502 - - - 1.2386 - 3.4 0.655 - 430.4 1 2 1 0.0025 16 0 0 0 8.32E+06 1.78E+07 - - - 8.9819 0.9988 221125_WJC_METTL3_EV_vs_WT_F07.16183.16183.4 0.0047 Nov-84 R.DYNKYEEGINIHLAK.K "sp|Q12996|CSTF3_HUMAN,tr|E9PLP8|E9PLP8_HUMAN" 2 1805.8948 0.77 102891 16183 4 1805.895918 452.481 Cleavage stimulation factor subunit 3 OS=Homo sapiens OX=9606 GN=CSTF3 PE=1 SV=1 5.45 2759 - 515935 - - - 0.6113 - 1.948 0.36 - 59.4 1 2 1 0.0011 15 0 0 0 2.83E+07 3.70E+07 - - - 2.5977 0.9996 221125_WJC_METTL3_EV_vs_WT_F07.16184.16184.3 3.18E-07 13/60 K.VILHLKEDQTEYLEER.R "sp|P08238|HS90B_HUMAN,sp|Q58FF6|H90B4_HUMAN,sp|Q58FF7|H90B3_HUMAN,sp|P07900|HS90A_HUMAN,tr|G3V2J8|G3V2J8_HUMAN" 5 2014.0371 0.47 102892 16184 3 2014.045177 672.353 Heat shock protein HSP 90-beta OS=Homo sapiens OX=9606 GN=HSP90AB1 PE=1 SV=4 4.57 2759.1 - 495357 - - - 3.9999 - 3.019 0.585 - 237.8 1 2 1 0.0081 16 0 0 0 8.32E+06 1.77E+07 - - - 7.895 0.9916 221125_WJC_METTL3_EV_vs_WT_F07.16185.16185.3 0.00884 Aug-60 R.LSFPSIK[136.11]PDTDQTLK[136.11]K[136.11].E "sp|Q92785|REQU_HUMAN,tr|J3KMZ8|J3KMZ8_HUMAN" 2 1841.0361 1.33 102893 16185 3 1841.03961 614.686 Zinc finger protein ubi-d4 OS=Homo sapiens OX=9606 GN=DPF2 PE=1 SV=2 8.5 2759.3 - 237405 - - - 1.9255 - 1.597 0.229 - 51.8 1 2 0 0.0035 16 0 0 0 1.18E+08 8.89E+07 - - - 2.2933 0.9984 221125_WJC_METTL3_EV_vs_WT_F07.16186.16186.3 0.00157 Oct-64 R.LTEADYLSSHLTEGPHR[166.11].V "sp|Q9BRJ7|TIRR_HUMAN,tr|W4VSQ8|W4VSQ8_HUMAN,tr|K7EIN2|K7EIN2_HUMAN,tr|K7ENA3|K7ENA3_HUMAN" 4 1934.9362 5.05 102894 16186 3 1934.929753 645.986 Tudor-interacting repair regulator protein OS=Homo sapiens OX=9606 GN=NUDT16L1 PE=1 SV=1 5.27 2759.4 - 225421 - - - -3.319 - 1.881 0.359 - 27.9 1 2 0 -0.0064 17 0 0 0 3.65E+07 7.24E+06 - - - 4.1368 0.9998 221125_WJC_METTL3_EV_vs_WT_F07.16190.16190.4 5.48E-07 15/84 K.FKVESEQQYFEIEKR.L "sp|P12270|TPR_HUMAN,tr|Q5SWX9|Q5SWX9_HUMAN" 2 1958.9738 3.51 102896 16190 4 1958.975927 490.7507 Nucleoprotein TPR OS=Homo sapiens OX=9606 GN=TPR PE=1 SV=3 4.95 2759.9 - 2.37E+06 - - - 1.0899 - 2.853 0.476 - 268.7 1 2 1 0.0021 15 0 0 0 3.99E+07 1.14E+07 - - - 3.7436 0.9999 221125_WJC_METTL3_EV_vs_WT_F07.16195.16195.3 2.43E-07 15/68 R.EK[136.11]TPLIDLC[160.03]DGQADQAAK[136.11].V "sp|Q9NZB2|F120A_HUMAN,tr|A0A0C4DG79|A0A0C4DG79_HUMAN,tr|A0A494C0Y9|A0A494C0Y9_HUMAN" 3 1987.9856 0.88 102901 16195 3 1987.983339 663.6691 Constitutive coactivator of PPAR-gamma-like protein 1 OS=Homo sapiens OX=9606 GN=FAM120A PE=1 SV=2 4.23 2760.3 - 852409 - - - -1.1152 - 3.275 0.489 - 283 1 2 1 -0.0022 18 0 0 0 2.84E+07 3.23E+07 - - - 6.9453 0.9998 221125_WJC_METTL3_EV_vs_WT_F07.16198.16198.3 1.89E-05 13/96 R.ISSVLAGGSC[160.03]RAPSTYGGGLSVSSR.F sp|P08779|K1C16_HUMAN 1 2425.202 999 102904 16198 3 2425.201868 809.4079 "Keratin, type I cytoskeletal 16 OS=Homo sapiens OX=9606 GN=KRT16 PE=1 SV=4" 9.5 2760.7 - 451070 - - - -0.0429 - 2.636 0.487 - 125.3 1 2 1 -0.0001 25 0 0 0 3.61E+06 0.00E+00 - - - 6.1995 1 221125_WJC_METTL3_EV_vs_WT_F07.16203.16203.4 1.48E-06 18/114 R.LSPGGSLADAWAHQEGTHPK.D "sp|Q9UHD2|TBK1_HUMAN,tr|A0A7I2V646|A0A7I2V646_HUMAN,tr|A0A494C045|A0A494C045_HUMAN,tr|A0A494C1M6|A0A494C1M6_HUMAN,tr|A0A494C0A8|A0A494C0A8_HUMAN,tr|A0A7I2V4W4|A0A7I2V4W4_HUMAN,tr|A0A7I2V463|A0A7I2V463_HUMAN,tr|A0A494C148|A0A494C148_HUMAN,tr|A0A494C0X2|A0A494C0X2_HUMAN,tr|A0A7I2V387|A0A7I2V387_HUMAN,tr|A0A7I2V2N0|A0A7I2V2N0_HUMAN,tr|A0A494C167|A0A494C167_HUMAN,tr|A0A7I2V2F4|A0A7I2V2F4_HUMAN,tr|A0A494C0R4|A0A494C0R4_HUMAN,tr|A0A7I2V643|A0A7I2V643_HUMAN" 15 2057.9919 0.83 102908 16203 4 2057.992135 515.5053 Serine\threonine-protein kinase TBK1 OS=Homo sapiens OX=9606 GN=TBK1 PE=1 SV=1 5.99 2761.3 - 1.57E+06 - - - 0.1132 - 3.766 0.566 - 250.3 1 2 0 0.0002 20 0 0 0 2.84E+07 3.42E+07 - - - 4.5957 1 221125_WJC_METTL3_EV_vs_WT_F07.16204.16204.4 7.59E-05 11/108 R.GLLQDDAHPTLVTYADHSK[136.11].L "sp|Q86U44|MTA70_HUMAN,tr|F5H6D8|F5H6D8_HUMAN,tr|H0YFV6|H0YFV6_HUMAN,tr|B4DTN4|B4DTN4_HUMAN" 4 2088.0367 0.03 102909 16204 4 2088.036499 523.0165 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 5.13 2761.4 - 6.77E+06 - - - -0.1121 - 2.363 0.504 - 125.6 1 2 0 -0.0002 19 0 0 0 1.75E+06 5.74E+07 - - - 3.9036 0.9987 221125_WJC_METTL3_EV_vs_WT_F07.16205.16205.4 0.00131 Oct-90 K.VILHLK[136.11]EDQTEYLEER[166.11].R "sp|P08238|HS90B_HUMAN,sp|Q58FF6|H90B4_HUMAN,sp|Q58FF7|H90B3_HUMAN,sp|P07900|HS90A_HUMAN,tr|G3V2J8|G3V2J8_HUMAN" 5 2032.0596 0.7 102910 16205 4 2032.059942 509.0222 Heat shock protein HSP 90-beta OS=Homo sapiens OX=9606 GN=HSP90AB1 PE=1 SV=4 4.57 2761.5 - 1.10E+06 - - - 0.1727 - 1.865 0.357 - 91.3 1 2 1 0.0004 16 0 0 0 1.22E+07 1.75E+07 - - - 2.5528 0.9999 221125_WJC_METTL3_EV_vs_WT_F07.16206.16206.3 4.69E-06 15/60 K.TDEDEKTILNLENSNK.S sp|Q8IX12|CCAR1_HUMAN 1 1861.8905 0.93 102911 16206 3 1861.892544 621.6374 Cell division cycle and apoptosis regulator protein 1 OS=Homo sapiens OX=9606 GN=CCAR1 PE=1 SV=2 4.18 2761.6 - 907490 - - - 1.0892 - 3.124 0.573 - 301.9 1 2 1 0.002 16 0 0 0 1.77E+07 1.90E+07 - - - 7.8506 0.9997 221125_WJC_METTL3_EV_vs_WT_F07.16207.16207.4 0.00421 13/90 R.TTSNTLHYIHIEQLDK[136.11].L sp|Q7Z6Z7|HUWE1_HUMAN 1 1919.9832 0.63 102912 16207 4 1919.982869 481.0031 E3 ubiquitin-protein ligase HUWE1 OS=Homo sapiens OX=9606 GN=HUWE1 PE=1 SV=3 5.92 2761.7 - 781733 - - - -0.1938 - 3.039 0.352 - 141.8 1 2 0 -0.0004 16 0 0 0 6.42E+06 1.02E+07 - - - 2.6812 1 221125_WJC_METTL3_EV_vs_WT_F07.16208.16208.4 2.43E-08 19/96 R.LTEADYLSSHLTEGPHR[166.11].V "sp|Q9BRJ7|TIRR_HUMAN,tr|W4VSQ8|W4VSQ8_HUMAN,tr|K7EIN2|K7EIN2_HUMAN,tr|K7ENA3|K7ENA3_HUMAN" 4 1934.9362 1.28 102913 16208 4 1934.936218 484.7413 Tudor-interacting repair regulator protein OS=Homo sapiens OX=9606 GN=NUDT16L1 PE=1 SV=1 5.27 2761.8 - 689559 - - - 0.0222 - 3.294 0.637 - 292.1 1 2 0 0 17 0 0 0 1.16E+07 9.03E+06 - - - 5.1843 0.9999 221125_WJC_METTL3_EV_vs_WT_F07.16216.16216.3 3.37E-06 20/76 R.LSPGGSLADAWAHQEGTHPK.D "sp|Q9UHD2|TBK1_HUMAN,tr|A0A7I2V646|A0A7I2V646_HUMAN,tr|A0A494C045|A0A494C045_HUMAN,tr|A0A494C1M6|A0A494C1M6_HUMAN,tr|A0A494C0A8|A0A494C0A8_HUMAN,tr|A0A7I2V4W4|A0A7I2V4W4_HUMAN,tr|A0A7I2V463|A0A7I2V463_HUMAN,tr|A0A494C148|A0A494C148_HUMAN,tr|A0A494C0X2|A0A494C0X2_HUMAN,tr|A0A7I2V387|A0A7I2V387_HUMAN,tr|A0A7I2V2N0|A0A7I2V2N0_HUMAN,tr|A0A494C167|A0A494C167_HUMAN,tr|A0A7I2V2F4|A0A7I2V2F4_HUMAN,tr|A0A494C0R4|A0A494C0R4_HUMAN,tr|A0A7I2V643|A0A7I2V643_HUMAN" 15 2057.9919 4.07 102919 16216 3 2057.991539 687.0046 Serine\threonine-protein kinase TBK1 OS=Homo sapiens OX=9606 GN=TBK1 PE=1 SV=1 5.99 2762.8 - 563204 - - - -0.1764 - 3.638 0.377 - 450.8 1 2 0 -0.0004 20 0 0 0 8.96E+06 2.20E+06 - - - 5.8761 0.9974 221125_WJC_METTL3_EV_vs_WT_F07.16222.16222.2 0.79 12-Jul K.FASFIDK.V "sp|Q86Y46|K2C73_HUMAN,sp|Q7RTS7|K2C74_HUMAN,sp|Q9NSB2|KRT84_HUMAN,sp|P48668|K2C6C_HUMAN,sp|Q3SY84|K2C71_HUMAN,sp|P05787|K2C8_HUMAN,sp|Q01546|K22O_HUMAN,sp|P19013|K2C4_HUMAN,sp|Q7Z794|K2C1B_HUMAN,sp|Q8N1N4|K2C78_HUMAN,sp|P12035|K2C3_HUMAN,sp|P04264|K2C1_HUMAN,sp|P04259|K2C6B_HUMAN,sp|P13647|K2C5_HUMAN,sp|P35908|K22E_HUMAN,sp|Q14CN4|K2C72_HUMAN,sp|P08729|K2C7_HUMAN,sp|O95678|K2C75_HUMAN,sp|Q5XKE5|K2C79_HUMAN,sp|P02538|K2C6A_HUMAN,tr|F8VUG2|F8VUG2_HUMAN,tr|F8W0C6|F8W0C6_HUMAN,tr|F8W1U3|F8W1U3_HUMAN,tr|H0YHD9|H0YHD9_HUMAN,tr|F8W1S1|F8W1S1_HUMAN,tr|F8VS61|F8VS61_HUMAN" 26 826.4225 104.08 102923 16222 2 826.422703 414.2185 "Keratin, type II cytoskeletal 73 OS=Homo sapiens OX=9606 GN=KRT73 PE=1 SV=1" 5.84 2763.6 - 503677 - - - 0.2396 - 1.528 0.164 - 143 1 2 0 0.0002 7 0 0 0 2.37E+07 2.28E+05 - - - 1.5956 1 221125_WJC_METTL3_EV_vs_WT_F07.16226.16226.3 2.61E-10 20/80 K.GGGEEPGKLPEPAEEESQVLR.G "sp|Q6ZN17|LN28B_HUMAN,tr|A0A1B0GTK2|A0A1B0GTK2_HUMAN,tr|A0A1B0GVD3|A0A1B0GVD3_HUMAN" 3 2207.0706 2.22 102927 16226 3 2207.065282 736.6975 Protein lin-28 homolog B OS=Homo sapiens OX=9606 GN=LIN28B PE=1 SV=1 4.21 2764.1 - 455998 - - - -2.4122 - 3.782 0.635 - 666.1 1 2 1 -0.0053 21 0 0 0 2.68E+07 1.21E+07 - - - 8.8074 1 221125_WJC_METTL3_EV_vs_WT_F07.16231.16231.3 1.30E-10 21/64 K.GYPHLC[160.03]SIC[160.03]DLPVHSNK.E "sp|P43243|MATR3_HUMAN,tr|A8MXP9|A8MXP9_HUMAN,tr|D6R991|D6R991_HUMAN,tr|A0A0R4J2E8|A0A0R4J2E8_HUMAN,tr|H0Y8T4|H0Y8T4_HUMAN,tr|D6REM6|D6REM6_HUMAN" 6 1995.9295 1.34 102930 16231 3 1995.931192 666.3171 Matrin-3 OS=Homo sapiens OX=9606 GN=MATR3 PE=1 SV=2 6.9 2764.8 - 4.11E+06 - - - 0.8467 - 3.552 0.639 - 526.7 1 2 0 0.0017 17 0 0 0 3.86E+08 2.89E+08 - - - 8.8659 1 221125_WJC_METTL3_EV_vs_WT_F07.16232.16232.3 5.46E-09 25/84 R.AVKPEPTNSSVEVSPDIYQQVR.D "sp|Q9UPW6|SATB2_HUMAN,tr|C9JR56|C9JR56_HUMAN" 2 2442.2391 7.62 102931 16232 3 2442.23929 815.087 DNA-binding protein SATB2 OS=Homo sapiens OX=9606 GN=SATB2 PE=1 SV=2 4.68 2764.9 - 1.51E+06 - - - 0.0909 - 3.914 0.592 - 562 1 2 0 0.0002 22 0 0 0 1.98E+08 2.60E+07 - - - 8.3753 0.9999 221125_WJC_METTL3_EV_vs_WT_F07.16233.16233.4 0.000635 14/102 R.GSLDYR[166.11]PLTTADPIDEHR[166.11].L "sp|O00139|KIF2A_HUMAN,tr|D6R9M0|D6R9M0_HUMAN,tr|A0A6Q8PFA6|A0A6Q8PFA6_HUMAN,tr|A0A6Q8PGG1|A0A6Q8PGG1_HUMAN,tr|A0A6Q8PGH7|A0A6Q8PGH7_HUMAN,tr|A0A6Q8PG37|A0A6Q8PG37_HUMAN,tr|A0A6Q8PH57|A0A6Q8PH57_HUMAN" 7 2075.0187 0.22 102932 16233 4 2075.021107 519.7619 Kinesin-like protein KIF2A OS=Homo sapiens OX=9606 GN=KIF2A PE=1 SV=3 4.66 2765 - 1.16E+06 - - - 1.1735 - 2.374 0.433 - 165.9 1 2 0 0.0024 18 0 0 0 1.33E+08 6.00E+08 - - - 3.2903 1 221125_WJC_METTL3_EV_vs_WT_F07.16235.16235.3 1.13E-05 17/84 R.AVK[136.11]PEPTNSSVEVSPDIYQQVR[166.11].D "sp|Q9UPW6|SATB2_HUMAN,tr|C9JR56|C9JR56_HUMAN" 2 2460.2615 7.62 102934 16235 3 2460.265104 821.0945 DNA-binding protein SATB2 OS=Homo sapiens OX=9606 GN=SATB2 PE=1 SV=2 4.68 2765.2 - 335216 - - - 1.4494 - 3.488 0.535 - 226.1 1 2 0 0.0036 22 0 0 0 1.98E+08 2.60E+07 - - - 7.4657 1 221125_WJC_METTL3_EV_vs_WT_F07.16238.16238.3 2.10E-09 16/64 K.GYPHLC[160.03]SIC[160.03]DLPVHSNK[136.11].E "sp|P43243|MATR3_HUMAN,tr|A8MXP9|A8MXP9_HUMAN,tr|D6R991|D6R991_HUMAN,tr|A0A0R4J2E8|A0A0R4J2E8_HUMAN,tr|H0Y8T4|H0Y8T4_HUMAN,tr|D6REM6|D6REM6_HUMAN" 6 2003.9437 1.34 102935 16238 3 2003.945706 668.9885 Matrin-3 OS=Homo sapiens OX=9606 GN=MATR3 PE=1 SV=2 6.9 2765.6 - 3.77E+06 - - - 1 - 3.252 0.687 - 297.7 1 2 0 0.002 17 0 0 0 3.91E+08 2.91E+08 - - - 9.178 0.9999 221125_WJC_METTL3_EV_vs_WT_F07.16239.16239.4 3.39E-05 Nov-84 K.TVVLHIDGLDDTSRR.N "sp|Q9NVT9|ARMC1_HUMAN,tr|E5RJ86|E5RJ86_HUMAN" 2 1695.8904 1.54 102936 16239 4 1695.894242 424.9799 Armadillo repeat-containing protein 1 OS=Homo sapiens OX=9606 GN=ARMC1 PE=1 SV=1 5.27 2765.8 - 259377 - - - 2.2672 - 2.116 0.481 - 104.6 1 2 0 0.0038 15 0 0 0 2.07E+07 1.35E+07 - - - 3.6797 0.9999 221125_WJC_METTL3_EV_vs_WT_F07.16242.16242.3 1.57E-05 13/64 R.LTEADYLSSHLTEGPHR.V "sp|Q9BRJ7|TIRR_HUMAN,tr|W4VSQ8|W4VSQ8_HUMAN,tr|K7EIN2|K7EIN2_HUMAN,tr|K7ENA3|K7ENA3_HUMAN" 4 1924.9279 0.95 102939 16242 3 1924.929812 642.6499 Tudor-interacting repair regulator protein OS=Homo sapiens OX=9606 GN=NUDT16L1 PE=1 SV=1 5.27 2766.1 - 319413 - - - 0.9907 - 2.613 0.445 - 202 1 2 0 0.0019 17 0 0 0 5.59E+06 5.87E+06 - - - 5.9273 0.9996 221125_WJC_METTL3_EV_vs_WT_F07.16246.16246.3 2.23E-09 18/64 K.LDK[136.11]SQIHDIVLVGGSTR[166.11].L "sp|P11142|HSP7C_HUMAN,tr|E9PNE6|E9PNE6_HUMAN,tr|A8K7Q2|A8K7Q2_HUMAN,tr|E9PKE3|E9PKE3_HUMAN,tr|E9PN89|E9PN89_HUMAN" 5 1855.0282 0.15 102941 16246 3 1855.029365 619.35 Heat shock cognate 71 kDa protein OS=Homo sapiens OX=9606 GN=HSPA8 PE=1 SV=1 6.75 2766.6 - 1.07E+06 - - - 0.6113 - 3.456 0.332 - 335.9 1 2 1 0.0011 17 0 0 0 1.66E+08 1.11E+09 - - - 5.3741 1 221125_WJC_METTL3_EV_vs_WT_F07.16247.16247.3 8.60E-07 14/60 R.LSFPSIKPDTDQTLKK.E "sp|Q92785|REQU_HUMAN,tr|J3KMZ8|J3KMZ8_HUMAN" 2 1816.9935 1.32 102942 16247 3 1816.994676 606.6718 Zinc finger protein ubi-d4 OS=Homo sapiens OX=9606 GN=DPF2 PE=1 SV=2 8.5 2766.8 - 1.02E+06 - - - 0.6665 - 2.813 0.495 - 207.2 1 2 0 0.0012 16 0 0 0 1.19E+08 8.95E+07 - - - 6.7122 0.9999 221125_WJC_METTL3_EV_vs_WT_F07.16248.16248.4 9.02E-09 19/102 K.FLYQLHETEKEDLIREER.S "sp|O75643|U520_HUMAN,tr|A0A494C1A5|A0A494C1A5_HUMAN" 2 2347.1808 2.56 102943 16248 4 2347.182193 587.8025 U5 small nuclear ribonucleoprotein 200 kDa helicase OS=Homo sapiens OX=9606 GN=SNRNP200 PE=1 SV=2 4.7 2766.9 - 1.50E+06 - - - 0.5828 - 3.029 0.587 - 237.6 1 2 2 0.0014 18 0 0 0 9.23E+07 3.61E+07 - - - 4.7145 0.9999 221125_WJC_METTL3_EV_vs_WT_F07.16249.16249.4 2.24E-05 19/84 R.R[166.11]FELYFQGPSSNK[136.11]PR[166.11].V "sp|P33993|MCM7_HUMAN,tr|C9J8M6|C9J8M6_HUMAN" 2 1852.9579 1.26 102944 16249 4 1852.96017 464.2467 DNA replication licensing factor MCM7 OS=Homo sapiens OX=9606 GN=MCM7 PE=1 SV=4 9.99 2766.9 - 886544 - - - 1.2483 - 2.962 0.447 - 298.9 1 2 0 0.0023 15 0 0 0 2.80E+07 2.23E+07 - - - 3.5046 0.9997 221125_WJC_METTL3_EV_vs_WT_F07.16250.16250.3 0.00719 Dec-64 K.SSQGSEFLEEPDKLEEK.T sp|Q5W0B1|OBI1_HUMAN 1 1950.9058 2.19 102945 16250 3 1950.903147 651.3092 ORC ubiquitin ligase 1 OS=Homo sapiens OX=9606 GN=OBI1 PE=1 SV=1 4.14 2767.1 - 626162 - - - -1.3763 - 2.586 0.43 - 120.9 1 2 1 -0.0027 17 0 0 0 2.34E+07 1.07E+07 - - - 5.7336 0.9903 221125_WJC_METTL3_EV_vs_WT_F07.16253.16253.4 0.0395 Nov-72 R.QAIEDELR[166.11]EHIEK[136.11].L "sp|Q5VTR2|BRE1A_HUMAN,tr|C9JWJ4|C9JWJ4_HUMAN,tr|C9JXC9|C9JXC9_HUMAN,tr|C9J0A5|C9J0A5_HUMAN" 4 1626.8332 0.84 102948 16253 4 1626.832032 407.7156 E3 ubiquitin-protein ligase BRE1A OS=Homo sapiens OX=9606 GN=RNF20 PE=1 SV=2 4.57 2767.5 - 323300 - - - -0.7303 - 1.886 0.256 - 114.9 1 2 1 -0.0012 13 0 0 0 3.53E+06 4.21E+06 - - - 1.6891 0.9987 221125_WJC_METTL3_EV_vs_WT_F07.16257.16257.4 0.0182 17/96 K.LDK[136.11]SQIHDIVLVGGSTR[166.11].L "sp|P11142|HSP7C_HUMAN,tr|E9PNE6|E9PNE6_HUMAN,tr|A8K7Q2|A8K7Q2_HUMAN,tr|E9PKE3|E9PKE3_HUMAN,tr|E9PN89|E9PN89_HUMAN" 5 1855.0282 0.35 102950 16257 4 1855.027584 464.7643 Heat shock cognate 71 kDa protein OS=Homo sapiens OX=9606 GN=HSPA8 PE=1 SV=1 6.75 2767.9 - 3.04E+06 - - - -0.3488 - 2.891 0.339 - 182.1 1 2 1 -0.0006 17 0 0 0 3.20E+08 9.11E+08 - - - 2.5451 0.9603 221125_WJC_METTL3_EV_vs_WT_F07.16260.16260.2 7.35E-07 13/36 R.GLLQDDAHPTLVTYADHSK[136.11].L "sp|Q86U44|MTA70_HUMAN,tr|F5H6D8|F5H6D8_HUMAN,tr|H0YFV6|H0YFV6_HUMAN,tr|B4DTN4|B4DTN4_HUMAN" 4 2088.0367 0.01 102953 16260 2 2089.031248 1045.0256 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 5.13 2768.2 - 299399 - - - 476.2919 - 2.587 0.591 - 371.2 1 2 0 0.9945 19 0 0 0 6.17E+07 6.25E+09 - - - 5.4307 1 221125_WJC_METTL3_EV_vs_WT_F07.16265.16265.3 8.00E-06 Dec-56 R.K[136.11]FDFDAC[160.03]NEVPPAPK[136.11].E "sp|Q14151|SAFB2_HUMAN,sp|Q15424|SAFB1_HUMAN" 2 1749.8367 4.06 102956 16265 3 1749.837746 584.2862 Scaffold attachment factor B2 OS=Homo sapiens OX=9606 GN=SAFB2 PE=1 SV=1 4.56 2768.8 - 591606 - - - 0.5938 - 2.477 0.484 - 159.6 1 2 0 0.001 15 0 0 0 6.98E+07 1.72E+07 - - - 6.3027 0.9998 221125_WJC_METTL3_EV_vs_WT_F07.16266.16266.4 9.06E-08 20/84 R.RFELYFQGPSSNKPR.V "sp|P33993|MCM7_HUMAN,tr|C9J8M6|C9J8M6_HUMAN" 2 1824.9271 1.23 102957 16266 4 1824.925197 457.2391 DNA replication licensing factor MCM7 OS=Homo sapiens OX=9606 GN=MCM7 PE=1 SV=4 9.99 2768.9 - 995661 - - - -1.0521 - 3.52 0.37 - 374 1 2 0 -0.0019 15 0 0 0 2.73E+07 2.23E+07 - - - 2.8962 1 221125_WJC_METTL3_EV_vs_WT_F07.16267.16267.3 2.22E-14 19/96 K.LVQDVANNTNEEAGDGTTTATVLAR.S "sp|P10809|CH60_HUMAN,tr|C9JL25|C9JL25_HUMAN,tr|A0A7I2V2X6|A0A7I2V2X6_HUMAN,tr|A0A7I2YQK6|A0A7I2YQK6_HUMAN,tr|A0A7I2V599|A0A7I2V599_HUMAN,tr|E7EXB4|E7EXB4_HUMAN,tr|A0A7I2YQ71|A0A7I2YQ71_HUMAN,tr|E7ESH4|E7ESH4_HUMAN,tr|A0A7I2V5M1|A0A7I2V5M1_HUMAN,tr|A0A7I2V5K3|A0A7I2V5K3_HUMAN,tr|A0A7I2V369|A0A7I2V369_HUMAN" 11 2559.2413 1.38 102958 16267 3 2559.240964 854.0877 "60 kDa heat shock protein, mitochondrial OS=Homo sapiens OX=9606 GN=HSPD1 PE=1 SV=2" 3.92 2769 - 728696 - - - -0.1129 - 3.7 0.722 - 446.1 1 2 0 -0.0003 25 0 0 0 2.20E+09 1.59E+09 - - - 9.5995 0.99 221125_WJC_METTL3_EV_vs_WT_F07.16268.16268.4 3.67E-05 15/96 L.LQDDAHPTLVTYADHSK[136.11].L "sp|Q86U44|MTA70_HUMAN,tr|F5H6D8|F5H6D8_HUMAN,tr|H0YFV6|H0YFV6_HUMAN,tr|B4DTN4|B4DTN4_HUMAN" 4 1917.9312 0.01 102959 16268 4 1917.930041 480.4901 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 5.13 2769.1 - 643662 - - - -0.6074 - 2.589 0.43 - 127.7 1 1 0 -0.0012 17 0 0 0 1.42E+07 9.58E+08 - - - 3.2987 1 221125_WJC_METTL3_EV_vs_WT_F07.16271.16271.4 3.19E-10 21/114 K.ATDAMAHVAGFTVAHDVSAR.D "sp|Q6P2I3|FAH2B_HUMAN,sp|Q96GK7|FAH2A_HUMAN" 2 2025.9691 0.63 102960 16271 4 2025.966405 507.4995 Fumarylacetoacetate hydrolase domain-containing protein 2B OS=Homo sapiens OX=9606 GN=FAHD2B PE=1 SV=1 5.98 2769.5 - 556776 - - - -1.3095 - 3.61 0.573 - 384 1 2 0 -0.0027 20 0 0 0 3.17E+07 5.05E+07 - - - 4.6418 0.9826 221125_WJC_METTL3_EV_vs_WT_F07.16272.16272.2 0.00193 Jun-40 R.LLEGEDAHLSSSQFSSGSQSS.R sp|P02533|K1C14_HUMAN 1 2151.9556 - 102961 16272 2 2151.952419 1076.9851 "Keratin, type I cytoskeletal 14 OS=Homo sapiens OX=9606 GN=KRT14 PE=1 SV=4" 4.13 2769.6 - 339755 - - - -1.4949 - 1.737 0.508 - 63.2 1 1 0 -0.0032 21 0 0 0 - - - - - 4.1496 0.9888 221125_WJC_METTL3_EV_vs_WT_F07.16273.16273.3 3.28E-06 18/60 L.QDDAHPTLVTYADHSK[136.11].L "sp|Q86U44|MTA70_HUMAN,tr|F5H6D8|F5H6D8_HUMAN,tr|H0YFV6|H0YFV6_HUMAN,tr|B4DTN4|B4DTN4_HUMAN" 4 1804.8471 0.01 102962 16273 3 1804.840866 602.623 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 5.13 2769.7 - 2.67E+06 - - - -3.4773 - 2.716 0.532 - 410 1 1 0 -0.0063 16 0 0 0 2.58E+07 2.60E+09 - - - 7.0332 1 221125_WJC_METTL3_EV_vs_WT_F07.16281.16281.3 3.18E-13 22/96 K.LVQDVANNTNEEAGDGTTTATVLAR[166.11].S "sp|P10809|CH60_HUMAN,tr|C9JL25|C9JL25_HUMAN,tr|A0A7I2V2X6|A0A7I2V2X6_HUMAN,tr|A0A7I2YQK6|A0A7I2YQK6_HUMAN,tr|A0A7I2V599|A0A7I2V599_HUMAN,tr|E7EXB4|E7EXB4_HUMAN,tr|A0A7I2YQ71|A0A7I2YQ71_HUMAN,tr|E7ESH4|E7ESH4_HUMAN,tr|A0A7I2V5M1|A0A7I2V5M1_HUMAN,tr|A0A7I2V5K3|A0A7I2V5K3_HUMAN,tr|A0A7I2V369|A0A7I2V369_HUMAN" 11 2569.2495 1.38 102968 16281 3 2569.241834 857.4238 "60 kDa heat shock protein, mitochondrial OS=Homo sapiens OX=9606 GN=HSPD1 PE=1 SV=2" 3.92 2770.7 - 4.06E+06 - - - -2.9927 - 3.932 0.75 - 662.4 1 2 0 -0.0077 25 0 0 0 2.20E+09 1.59E+09 - - - 10.0495 1 221125_WJC_METTL3_EV_vs_WT_F07.16282.16282.3 3.28E-07 24/64 K.LDKSQIHDIVLVGGSTR.L "sp|P11142|HSP7C_HUMAN,tr|E9PNE6|E9PNE6_HUMAN,tr|A8K7Q2|A8K7Q2_HUMAN,tr|E9PKE3|E9PKE3_HUMAN,tr|E9PN89|E9PN89_HUMAN" 5 1837.0058 0.15 102969 16282 3 1837.002294 613.3425 Heat shock cognate 71 kDa protein OS=Homo sapiens OX=9606 GN=HSPA8 PE=1 SV=1 6.75 2770.8 - 2.19E+06 - - - -1.8873 - 3.982 0.603 - 811.7 1 2 1 -0.0035 17 0 0 0 1.66E+08 1.11E+09 - - - 8.7527 0.9995 221125_WJC_METTL3_EV_vs_WT_F07.16287.16287.4 6.38E-06 18/102 K.FLYQLHETEK[136.11]EDLIR[166.11]EER[166.11].S "sp|O75643|U520_HUMAN,tr|A0A494C1A5|A0A494C1A5_HUMAN" 2 2375.2116 2.51 102972 16287 4 2375.205006 594.8102 U5 small nuclear ribonucleoprotein 200 kDa helicase OS=Homo sapiens OX=9606 GN=SNRNP200 PE=1 SV=2 4.7 2771.4 - 2.33E+06 - - - -2.7614 - 3.324 0.464 - 258.4 1 2 2 -0.0066 18 0 0 0 9.04E+07 3.61E+07 - - - 3.6743 1 221125_WJC_METTL3_EV_vs_WT_F07.16289.16289.3 3.57E-10 21/64 K.ANELPQPPVPEPANAGK.R "sp|P78347|GTF2I_HUMAN,tr|A0A494C1K3|A0A494C1K3_HUMAN" 2 1727.8842 2.62 102973 16289 3 1727.880885 576.9687 General transcription factor II-I OS=Homo sapiens OX=9606 GN=GTF2I PE=1 SV=2 4.53 2771.6 - 5.29E+06 - - - -1.9469 - 3.895 0.629 - 567.2 1 2 0 -0.0034 17 0 0 0 3.29E+08 1.25E+08 - - - 8.9868 0.9995 221125_WJC_METTL3_EV_vs_WT_F07.16290.16290.4 3.65E-05 16/96 K.LDKSQIHDIVLVGGSTR.L "sp|P11142|HSP7C_HUMAN,tr|E9PNE6|E9PNE6_HUMAN,tr|A8K7Q2|A8K7Q2_HUMAN,tr|E9PKE3|E9PKE3_HUMAN,tr|E9PN89|E9PN89_HUMAN" 5 1837.0058 0.39 102974 16290 4 1837.00174 460.2587 Heat shock cognate 71 kDa protein OS=Homo sapiens OX=9606 GN=HSPA8 PE=1 SV=1 6.75 2771.6 - 2.74E+06 - - - -2.1889 - 2.849 0.435 - 128.8 1 2 1 -0.004 17 0 0 0 3.60E+08 9.13E+08 - - - 3.3746 0.9961 221125_WJC_METTL3_EV_vs_WT_F07.16291.16291.3 1.95E-10 17/56 Q.DDAHPTLVTYADHSK[136.11].L "sp|Q86U44|MTA70_HUMAN,tr|F5H6D8|F5H6D8_HUMAN,tr|H0YFV6|H0YFV6_HUMAN,tr|B4DTN4|B4DTN4_HUMAN" 4 1676.7886 0.01 102975 16291 3 1676.783457 559.9368 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 5.13 2771.7 - 3.50E+06 - - - -3.0457 - 3.196 0.611 - 414.7 1 1 0 -0.0051 15 0 0 0 4.44E+06 5.99E+08 - - - 8.3825 0.9999 221125_WJC_METTL3_EV_vs_WT_F07.16295.16295.3 6.60E-09 20/64 K.ANELPQPPVPEPANAGK[136.11].R "sp|P78347|GTF2I_HUMAN,tr|A0A494C1K3|A0A494C1K3_HUMAN" 2 1735.8984 2.61 102976 16295 3 1735.894084 579.6401 General transcription factor II-I OS=Homo sapiens OX=9606 GN=GTF2I PE=1 SV=2 4.53 2772.3 - 3.75E+06 - - - -2.5145 - 3.579 0.402 - 515 1 2 0 -0.0044 17 0 0 0 3.28E+08 1.25E+08 - - - 6.2419 0.9999 221125_WJC_METTL3_EV_vs_WT_F07.16297.16297.2 1.95E-08 15/32 K.ANELPQPPVPEPANAGK.R "sp|P78347|GTF2I_HUMAN,tr|A0A494C1K3|A0A494C1K3_HUMAN" 2 1727.8842 2.44 102977 16297 2 1727.884243 864.9494 General transcription factor II-I OS=Homo sapiens OX=9606 GN=GTF2I PE=1 SV=2 4.53 2772.5 - 5.28E+06 - - - -0.0035 - 2.467 0.565 - 532.3 1 2 0 0 17 0 0 0 4.32E+08 1.77E+08 - - - 5.4342 1 221125_WJC_METTL3_EV_vs_WT_F07.16301.16301.3 0.000707 23/76 R.QGQETAVAPSLVAPALNKPK.K sp|Q15691|MARE1_HUMAN 1 2018.116 0.85 102981 16301 3 2018.109361 673.7126 Microtubule-associated protein RP\EB family member 1 OS=Homo sapiens OX=9606 GN=MAPRE1 PE=1 SV=3 8.59 2772.9 - 872938 - - - -3.3095 - 4.325 0.579 - 496 1 2 0 -0.0067 20 0 0 0 2.30E+07 2.72E+07 - - - 8.5461 1 221125_WJC_METTL3_EV_vs_WT_F07.16305.16305.2 2.97E-09 20/32 K.LDK[136.11]SQIHDIVLVGGSTR[166.11].L "sp|P11142|HSP7C_HUMAN,tr|E9PNE6|E9PNE6_HUMAN,tr|A8K7Q2|A8K7Q2_HUMAN,tr|E9PKE3|E9PKE3_HUMAN,tr|E9PN89|E9PN89_HUMAN" 5 1855.0282 0.01 102982 16305 2 1855.029276 928.5214 Heat shock cognate 71 kDa protein OS=Homo sapiens OX=9606 GN=HSPA8 PE=1 SV=1 6.75 2773.4 - 3.04E+06 - - - 0.5633 - 3.208 0.603 - 526 1 2 1 0.001 17 0 0 0 1.04E+06 7.94E+07 - - - 6.3602 1 221125_WJC_METTL3_EV_vs_WT_F07.16306.16306.2 1.07E-11 19/30 L.QDDAHPTLVTYADHSK[136.11].L "sp|Q86U44|MTA70_HUMAN,tr|F5H6D8|F5H6D8_HUMAN,tr|H0YFV6|H0YFV6_HUMAN,tr|B4DTN4|B4DTN4_HUMAN" 4 1804.8471 0.001 102983 16306 2 1804.843416 903.4308 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 5.13 2773.6 - 1.51E+06 - - - -2.0644 - 3.087 0.666 - 844.3 1 1 0 -0.0037 16 0 0 0 0.00E+00 1.88E+08 - - - 6.7302 0.9999 221125_WJC_METTL3_EV_vs_WT_F07.16311.16311.4 9.09E-06 14/96 K.GYPHLC[160.03]SIC[160.03]DLPVHSNK.E "sp|P43243|MATR3_HUMAN,tr|A8MXP9|A8MXP9_HUMAN,tr|D6R991|D6R991_HUMAN,tr|A0A0R4J2E8|A0A0R4J2E8_HUMAN,tr|H0Y8T4|H0Y8T4_HUMAN,tr|D6REM6|D6REM6_HUMAN" 6 1995.9295 1.35 102985 16311 4 1995.924539 499.9897 Matrin-3 OS=Homo sapiens OX=9606 GN=MATR3 PE=1 SV=2 6.9 2774.2 - 1.15E+07 - - - -2.4866 - 2.374 0.518 - 93.2 1 2 0 -0.005 17 0 0 0 9.20E+08 6.80E+08 - - - 4.0335 1 221125_WJC_METTL3_EV_vs_WT_F07.16321.16321.2 2.68E-13 21/28 Q.DDAHPTLVTYADHSK[136.11].L "sp|Q86U44|MTA70_HUMAN,tr|F5H6D8|F5H6D8_HUMAN,tr|H0YFV6|H0YFV6_HUMAN,tr|B4DTN4|B4DTN4_HUMAN" 4 1676.7886 0.001 102990 16321 2 1676.781074 839.4016 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 5.13 2775.5 - 1.76E+06 - - - -4.4669 - 3.294 0.725 - 1244.1 1 1 0 -0.0075 15 0 0 0 0.00E+00 3.09E+08 - - - 7.3243 1 221125_WJC_METTL3_EV_vs_WT_F07.16325.16325.2 9.34E-17 29/48 K.LVQDVANNTNEEAGDGTTTATVLAR[166.11].S "sp|P10809|CH60_HUMAN,tr|C9JL25|C9JL25_HUMAN,tr|A0A7I2V2X6|A0A7I2V2X6_HUMAN,tr|A0A7I2YQK6|A0A7I2YQK6_HUMAN,tr|A0A7I2V599|A0A7I2V599_HUMAN,tr|E7EXB4|E7EXB4_HUMAN,tr|A0A7I2YQ71|A0A7I2YQ71_HUMAN,tr|E7ESH4|E7ESH4_HUMAN,tr|A0A7I2V5M1|A0A7I2V5M1_HUMAN,tr|A0A7I2V5K3|A0A7I2V5K3_HUMAN,tr|A0A7I2V369|A0A7I2V369_HUMAN" 11 2569.2495 2.41 102991 16325 2 2569.250577 1285.632 "60 kDa heat shock protein, mitochondrial OS=Homo sapiens OX=9606 GN=HSPD1 PE=1 SV=2" 3.92 2776.1 - 3.81E+06 - - - 0.4102 - 5.223 0.743 - 2690.2 1 2 0 0.0011 25 0 0 0 1.46E+08 6.04E+07 - - - 8.5926 0.9999 221125_WJC_METTL3_EV_vs_WT_F07.16330.16330.3 0.000308 19/72 R.GGGFFSGLGGKPSQDAANK.N "sp|P35658|NU214_HUMAN,tr|A0A494C0Y1|A0A494C0Y1_HUMAN,tr|A0A0A0MSW3|A0A0A0MSW3_HUMAN,tr|B7ZAV2|B7ZAV2_HUMAN,tr|A0A494C1F2|A0A494C1F2_HUMAN,tr|H0Y837|H0Y837_HUMAN" 6 1793.8697 3.84 102993 16330 3 1793.867099 598.9638 Nuclear pore complex protein Nup214 OS=Homo sapiens OX=9606 GN=NUP214 PE=1 SV=2 8.59 2776.7 - 3.55E+06 - - - -1.4288 - 2.682 0.395 - 313.8 1 2 0 -0.0026 19 0 0 0 3.52E+08 9.16E+07 - - - 5.3669 0.9977 221125_WJC_METTL3_EV_vs_WT_F07.16334.16334.4 6.08E-07 11/102 G.LLQDDAHPTLVTYADHSK[136.11].L "sp|Q86U44|MTA70_HUMAN,tr|F5H6D8|F5H6D8_HUMAN,tr|H0YFV6|H0YFV6_HUMAN,tr|B4DTN4|B4DTN4_HUMAN" 4 2031.0153 0.04 102995 16334 4 2031.012098 508.7611 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 5.13 2777.1 - 5.32E+06 - - - -1.5618 - 2.298 0.584 - 77.3 1 1 0 -0.0032 18 0 0 0 1.03E+07 2.75E+08 - - - 4.5933 1 221125_WJC_METTL3_EV_vs_WT_F07.16335.16335.2 8.30E-15 24/48 K.LVQDVANNTNEEAGDGTTTATVLAR.S "sp|P10809|CH60_HUMAN,tr|C9JL25|C9JL25_HUMAN,tr|A0A7I2V2X6|A0A7I2V2X6_HUMAN,tr|A0A7I2YQK6|A0A7I2YQK6_HUMAN,tr|A0A7I2V599|A0A7I2V599_HUMAN,tr|E7EXB4|E7EXB4_HUMAN,tr|A0A7I2YQ71|A0A7I2YQ71_HUMAN,tr|E7ESH4|E7ESH4_HUMAN,tr|A0A7I2V5M1|A0A7I2V5M1_HUMAN,tr|A0A7I2V5K3|A0A7I2V5K3_HUMAN,tr|A0A7I2V369|A0A7I2V369_HUMAN" 11 2559.2413 2.41 102996 16335 2 2559.23648 1280.6279 "60 kDa heat shock protein, mitochondrial OS=Homo sapiens OX=9606 GN=HSPD1 PE=1 SV=2" 3.92 2777.2 - 3.85E+06 - - - -1.865 - 4.747 0.769 - 1595.3 1 2 0 -0.0048 25 0 0 0 1.46E+08 6.04E+07 - - - 8.5486 1 221125_WJC_METTL3_EV_vs_WT_F07.16342.16342.4 1.02E-07 19/90 R.LSFPSIKPDTDQTLKK.E "sp|Q92785|REQU_HUMAN,tr|J3KMZ8|J3KMZ8_HUMAN" 2 1816.9935 1.31 102998 16342 4 1816.989935 455.2556 Zinc finger protein ubi-d4 OS=Homo sapiens OX=9606 GN=DPF2 PE=1 SV=2 8.5 2778.2 - 4.29E+06 - - - -1.9428 - 3.362 0.565 - 218.6 1 2 0 -0.0035 16 0 0 0 3.37E+08 2.57E+08 - - - 4.5699 1 221125_WJC_METTL3_EV_vs_WT_F07.16355.16355.3 2.97E-08 24/56 K.HIANYISGIQTIGHR[166.11].V sp|Q15393|SF3B3_HUMAN 1 1688.8986 0.7 102999 16355 3 1688.896126 563.9735 Splicing factor 3B subunit 3 OS=Homo sapiens OX=9606 GN=SF3B3 PE=1 SV=4 8.76 2780.4 - 6.59E+06 - - - -1.469 - 3.059 0.573 - 610.1 1 2 0 -0.0025 15 0 0 0 2.31E+08 3.31E+08 - - - 7.8452 0.9984 221125_WJC_METTL3_EV_vs_WT_F07.16359.16359.3 2.83E-07 14/48 D.AHPTLVTYADHSK[136.11].L "sp|Q86U44|MTA70_HUMAN,tr|F5H6D8|F5H6D8_HUMAN,tr|H0YFV6|H0YFV6_HUMAN,tr|B4DTN4|B4DTN4_HUMAN" 4 1446.7347 0 103001 16359 3 1446.73348 483.2522 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 6.96 2780.9 - 1.93E+06 - - - -0.8281 - 2.816 0.549 - 268.8 1 1 0 -0.0012 13 0 0 0 5.36E+05 1.28E+08 - - - 7.4675 0.9996 221125_WJC_METTL3_EV_vs_WT_F07.16361.16361.4 4.96E-05 15/96 K.GYPHLC[160.03]SIC[160.03]DLPVHSNK[136.11].E "sp|P43243|MATR3_HUMAN,tr|A8MXP9|A8MXP9_HUMAN,tr|D6R991|D6R991_HUMAN,tr|A0A0R4J2E8|A0A0R4J2E8_HUMAN,tr|H0Y8T4|H0Y8T4_HUMAN,tr|D6REM6|D6REM6_HUMAN" 6 2003.9437 1.35 103002 16361 4 2003.935081 501.9932 Matrin-3 OS=Homo sapiens OX=9606 GN=MATR3 PE=1 SV=2 6.9 2781.1 - 4.94E+06 - - - -4.302 - 2.051 0.479 - 104.3 1 2 0 -0.0086 17 0 0 0 9.17E+08 6.78E+08 - - - 3.6422 1 221125_WJC_METTL3_EV_vs_WT_F07.16371.16371.3 5.04E-09 30/128 K.LASVPAGGAVAVSAAPGSAAPAAGSAPAAAEEK.K "sp|P05387|RLA2_HUMAN,tr|H0YDD8|H0YDD8_HUMAN" 2 2773.4246 1.51 103005 16371 3 2773.425226 925.4822 60S acidic ribosomal protein P2 OS=Homo sapiens OX=9606 GN=RPLP2 PE=1 SV=1 4.53 2782.5 - 5.97E+06 - - - 0.2124 - 4.134 0.649 - 582.5 1 2 0 0.0006 33 0 0 0 2.62E+09 1.73E+09 - - - 9.0407 1 221125_WJC_METTL3_EV_vs_WT_F07.16373.16373.3 7.97E-07 18/60 R.EADSSSDYVNMDFTK[136.11]R[166.11].E "sp|O14654|IRS4_HUMAN,tr|A0A804CF45|A0A804CF45_HUMAN" 2 1881.817 0.62 103006 16373 3 1881.818422 628.2796 Insulin receptor substrate 4 OS=Homo sapiens OX=9606 GN=IRS4 PE=1 SV=1 4.23 2782.7 - 2.45E+06 - - - 0.7679 - 2.707 0.528 - 353.4 1 2 0 0.0014 16 0 0 0 1.32E+08 2.11E+08 - - - 6.9815 0.9995 221125_WJC_METTL3_EV_vs_WT_F07.16377.16377.3 0.482 22/128 K.LASVPAGGAVAVSAAPGSAAPAAGSAPAAAEEK[136.11].K "sp|P05387|RLA2_HUMAN,tr|H0YDD8|H0YDD8_HUMAN" 2 2781.4388 1.51 103007 16377 3 2781.430366 928.1536 60S acidic ribosomal protein P2 OS=Homo sapiens OX=9606 GN=RPLP2 PE=1 SV=1 4.53 2783.3 - 7.26E+06 - - - -3.0455 - 3.001 0.343 - 195.5 1 2 0 -0.0085 33 0 0 0 2.62E+09 1.73E+09 - - - 4.89 0.95 221125_WJC_METTL3_EV_vs_WT_F07.16381.16381.2 4.71E-06 13/20 H.PTLVTYADHSK[136.11].L "sp|Q86U44|MTA70_HUMAN,tr|F5H6D8|F5H6D8_HUMAN,tr|H0YFV6|H0YFV6_HUMAN,tr|B4DTN4|B4DTN4_HUMAN" 4 1238.6387 0.05 103009 16381 2 1238.6338 620.3266 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 7.16 2783.7 - 1.34E+06 - - - -3.9172 - 2.303 0.533 - 643 1 1 0 -0.0049 11 0 0 0 4.89E+06 1.00E+08 - - - 5.233 1 221125_WJC_METTL3_EV_vs_WT_F07.16388.16388.4 2.83E-07 Dec-96 R.R[166.11]APEEELPPLDPEEIR[166.11]K[136.11].R "sp|Q8IY67|RAVR1_HUMAN,tr|K7EKR9|K7EKR9_HUMAN,tr|E9PAU2|E9PAU2_HUMAN,tr|A0A087WZ13|A0A087WZ13_HUMAN" 4 2045.0788 1.12 103012 16388 4 2045.075889 512.277 Ribonucleoprotein PTB-binding 1 OS=Homo sapiens OX=9606 GN=RAVER1 PE=1 SV=1 4.42 2784.6 - 6.44E+06 - - - -1.4039 - 2.605 0.558 - 94.3 1 2 0 -0.0029 17 0 0 0 1.13E+09 1.02E+09 - - - 4.4145 1 221125_WJC_METTL3_EV_vs_WT_F07.16391.16391.3 2.28E-08 17/64 R.R[166.11]APEEELPPLDPEEIR[166.11]K[136.11].R "sp|Q8IY67|RAVR1_HUMAN,tr|K7EKR9|K7EKR9_HUMAN,tr|E9PAU2|E9PAU2_HUMAN,tr|A0A087WZ13|A0A087WZ13_HUMAN" 4 2045.0788 1.08 103013 16391 3 2045.0781 682.7002 Ribonucleoprotein PTB-binding 1 OS=Homo sapiens OX=9606 GN=RAVER1 PE=1 SV=1 4.42 2784.9 - 7.09E+06 - - - -0.3227 - 3.125 0.48 - 308.7 1 2 0 -0.0007 17 0 0 0 6.62E+08 6.10E+08 - - - 6.7699 1 221125_WJC_METTL3_EV_vs_WT_F07.16395.16395.4 6.53E-07 17/96 R.RAPEEELPPLDPEEIRK.R "sp|Q8IY67|RAVR1_HUMAN,tr|K7EKR9|K7EKR9_HUMAN,tr|E9PAU2|E9PAU2_HUMAN,tr|A0A087WZ13|A0A087WZ13_HUMAN" 4 2017.048 0.62 103015 16395 4 2017.043913 505.2693 Ribonucleoprotein PTB-binding 1 OS=Homo sapiens OX=9606 GN=RAVER1 PE=1 SV=1 4.42 2785.4 - 8.94E+06 - - - -2.0361 - 3.026 0.57 - 228.9 1 2 0 -0.0041 17 0 0 0 1.20E+09 1.94E+09 - - - 4.5706 1 221125_WJC_METTL3_EV_vs_WT_F07.16396.16396.3 5.14E-09 25/64 R.RAPEEELPPLDPEEIRK.R "sp|Q8IY67|RAVR1_HUMAN,tr|K7EKR9|K7EKR9_HUMAN,tr|E9PAU2|E9PAU2_HUMAN,tr|A0A087WZ13|A0A087WZ13_HUMAN" 4 2017.048 0.71 103016 16396 3 2017.042593 673.3566 Ribonucleoprotein PTB-binding 1 OS=Homo sapiens OX=9606 GN=RAVER1 PE=1 SV=1 4.42 2785.5 - 7.19E+06 - - - -2.6906 - 3.879 0.62 - 812.6 1 2 0 -0.0054 17 0 0 0 6.96E+08 9.79E+08 - - - 8.8755 1 221125_WJC_METTL3_EV_vs_WT_F07.16401.16401.3 7.43E-09 18/60 R.EADSSSDYVNMDFTKR.E "sp|O14654|IRS4_HUMAN,tr|A0A804CF45|A0A804CF45_HUMAN" 2 1863.7945 0.63 103018 16401 3 1863.787048 622.2721 Insulin receptor substrate 4 OS=Homo sapiens OX=9606 GN=IRS4 PE=1 SV=1 4.23 2786 - 2.43E+06 - - - -4.0021 - 3.373 0.643 - 408.9 1 2 0 -0.0075 16 0 0 0 1.32E+08 2.10E+08 - - - 8.8263 1 221125_WJC_METTL3_EV_vs_WT_F07.16405.16405.2 2.00E-06 24/36 R.GLLQDDAHPTLVTYADHSK.L "sp|Q86U44|MTA70_HUMAN,tr|F5H6D8|F5H6D8_HUMAN,tr|H0YFV6|H0YFV6_HUMAN,tr|B4DTN4|B4DTN4_HUMAN" 4 2080.0225 0.01 103019 16405 2 2080.015815 1041.0185 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 5.13 2786.6 - 1.28E+06 - - - -3.2298 - 3.665 0.605 - 824.2 1 2 0 -0.0067 19 0 0 0 6.17E+07 6.23E+09 - - - 6.7006 1 221125_WJC_METTL3_EV_vs_WT_F07.16411.16411.3 1.68E-11 30/72 R.AASPQDLAGGYTSSLAC[160.03]HR.A "sp|P51948|MAT1_HUMAN,tr|H0YJ92|H0YJ92_HUMAN" 2 1960.9061 3.07 103022 16411 3 1960.904381 654.6427 CDK-activating kinase assembly factor MAT1 OS=Homo sapiens OX=9606 GN=MNAT1 PE=1 SV=1 6.78 2787.4 - 2.47E+06 - - - -0.8889 - 4.926 0.637 - 1476.2 1 2 0 -0.0017 19 0 0 0 8.22E+07 2.67E+07 - - - 9.5589 1 221125_WJC_METTL3_EV_vs_WT_F07.16414.16414.2 9.24E-10 27/64 K.LASVPAGGAVAVSAAPGSAAPAAGSAPAAAEEK.K "sp|P05387|RLA2_HUMAN,tr|H0YDD8|H0YDD8_HUMAN" 2 2773.4246 4.13 103023 16414 2 2775.425447 1387.7196 60S acidic ribosomal protein P2 OS=Homo sapiens OX=9606 GN=RPLP2 PE=1 SV=1 4.53 2787.8 - 2.76E+06 - - - 721.4222 - 4.054 0.683 - 999.2 1 2 0 2.0008 33 0 0 0 8.80E+07 2.13E+07 - - - 6.8986 1 221125_WJC_METTL3_EV_vs_WT_F07.16440.16440.3 9.54E-15 17/80 K.NTDYTELHQQNTDLIYQTGPK.S sp|Q8TBA6|GOGA5_HUMAN 1 2478.1663 2.05 103032 16440 3 2478.157286 827.0627 Golgin subfamily A member 5 OS=Homo sapiens OX=9606 GN=GOLGA5 PE=1 SV=3 4.54 2791.4 - 3.98E+06 - - - -3.6362 - 3.561 0.709 - 323.2 1 2 0 -0.009 21 0 0 0 1.29E+08 6.28E+07 - - - 9.487 0.991 221125_WJC_METTL3_EV_vs_WT_F07.16444.16444.3 0.00025 14/64 K.K[136.11]IFVGGIK[136.11]EDTEEYNLR[166.11].D "sp|P51991|ROA3_HUMAN,tr|A0A7I2V5D8|A0A7I2V5D8_HUMAN,tr|A0A7I2V2R3|A0A7I2V2R3_HUMAN,tr|A0A7I2V4J6|A0A7I2V4J6_HUMAN,tr|A0A7I2V4G0|A0A7I2V4G0_HUMAN,tr|A0A7I2V402|A0A7I2V402_HUMAN" 6 2036.0789 0.75 103034 16444 3 2036.066556 679.7002 Heterogeneous nuclear ribonucleoprotein A3 OS=Homo sapiens OX=9606 GN=HNRNPA3 PE=1 SV=2 4.87 2791.9 - 1.33E+06 - - - -6.0508 - 3.139 0.386 - 302.9 1 2 1 -0.0123 17 0 0 0 2.00E+07 2.66E+07 - - - 5.73 1 221125_WJC_METTL3_EV_vs_WT_F07.16446.16446.4 4.19E-06 10/108 R.GLLQDDAHPTLVTYADHSK[136.11].L "sp|Q86U44|MTA70_HUMAN,tr|F5H6D8|F5H6D8_HUMAN,tr|H0YFV6|H0YFV6_HUMAN,tr|B4DTN4|B4DTN4_HUMAN" 4 2088.0367 0.03 103035 16446 4 2088.034506 523.0165 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 5.13 2792.1 - 1.05E+09 - - - -1.0666 - 2.334 0.551 - 85.3 1 2 0 -0.0022 19 0 0 0 4.24E+09 1.38E+11 - - - 4.308 0.9942 221125_WJC_METTL3_EV_vs_WT_F07.16447.16447.3 3.54E-06 15/64 L.LQDDAHPTLVTYADHSK[136.11].L "sp|Q86U44|MTA70_HUMAN,tr|F5H6D8|F5H6D8_HUMAN,tr|H0YFV6|H0YFV6_HUMAN,tr|B4DTN4|B4DTN4_HUMAN" 4 1917.9312 0.01 103036 16447 3 1917.925299 640.3177 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 5.13 2792.1 - 2.05E+07 - - - -3.0799 - 2.959 0.571 - 232.8 1 1 0 -0.0059 17 0 0 0 6.76E+07 4.86E+09 - - - 7.6451 0.9518 221125_WJC_METTL3_EV_vs_WT_F07.16449.16449.2 0.0129 16-Aug Q.VINDGDK[136.11]PK[136.11].V "sp|P0DMV8|HS71A_HUMAN,sp|P0DMV9|HS71B_HUMAN,tr|A0A0G2JIW1|A0A0G2JIW1_HUMAN" 3 1000.5524 0.05 103038 16449 2 1000.550423 501.2835 Heat shock 70 kDa protein 1A OS=Homo sapiens OX=9606 GN=HSPA1A PE=1 SV=1 5.93 2792.4 - 1.01E+06 - - - -1.9859 - 1.562 0.398 - 156.9 1 1 0 -0.002 9 0 0 0 1.26E+06 2.72E+07 - - - 3.2702 1 221125_WJC_METTL3_EV_vs_WT_F07.16454.16454.3 2.24E-12 21/80 K.NTDYTELHQQNTDLIYQTGPK[136.11].S sp|Q8TBA6|GOGA5_HUMAN 1 2486.1805 2.05 103039 16454 3 2486.177201 829.7341 Golgin subfamily A member 5 OS=Homo sapiens OX=9606 GN=GOLGA5 PE=1 SV=3 4.54 2793.1 - 3.24E+06 - - - -1.3257 - 3.299 0.614 - 173.7 1 2 0 -0.0033 21 0 0 0 1.29E+08 6.28E+07 - - - 8.2462 1 221125_WJC_METTL3_EV_vs_WT_F07.16466.16466.3 1.58E-07 18/68 K.EGPHYTPPIPNYQPPEGR[166.11].Y sp|Q9NQ50|RM40_HUMAN 1 2057.9835 1.75 103044 16466 3 2057.982039 687.0018 "39S ribosomal protein L40, mitochondrial OS=Homo sapiens OX=9606 GN=MRPL40 PE=1 SV=1" 5.4 2794.6 - 734286 - - - -0.69 - 3.289 0.543 - 314.5 1 2 0 -0.0014 18 0 0 0 1.69E+08 9.69E+07 - - - 7.5582 1 221125_WJC_METTL3_EV_vs_WT_F07.16477.16477.3 2.59E-12 18/64 R.SNAYHFPDEPYKDGYIR.N "sp|Q9NUQ7|UFSP2_HUMAN,tr|D6RGX2|D6RGX2_HUMAN,tr|H0YA18|H0YA18_HUMAN" 3 2070.9436 35.26 103049 16477 3 2070.95075 691.3218 Ufm1-specific protease 2 OS=Homo sapiens OX=9606 GN=UFSP2 PE=1 SV=3 5.36 2796.1 - 490119 - - - 3.4743 - 3.931 0.637 - 545.9 1 2 1 0.0072 17 0 0 0 1.66E+07 4.70E+05 - - - 9.0982 1 221125_WJC_METTL3_EV_vs_WT_F07.16478.16478.3 9.51E-07 17/56 K.NRPTSISWDGLDSGK.L sp|P30086|PEBP1_HUMAN 1 1631.7903 1.53 103050 16478 3 1631.787525 544.9374 Phosphatidylethanolamine-binding protein 1 OS=Homo sapiens OX=9606 GN=PEBP1 PE=1 SV=3 5.96 2796.3 - 1.53E+06 - - - -1.7306 - 3.074 0.555 - 477 1 2 0 -0.0028 15 0 0 0 3.75E+07 2.45E+07 - - - 7.6572 1 221125_WJC_METTL3_EV_vs_WT_F07.16479.16479.3 1.73E-14 24/92 K.LGLGLDDESNNQQAAATQSPGDSR.R "sp|Q09472|EP300_HUMAN,tr|A0A669KB12|A0A669KB12_HUMAN" 2 2443.1211 10.88 103051 16479 3 2443.111225 815.381 Histone acetyltransferase p300 OS=Homo sapiens OX=9606 GN=EP300 PE=1 SV=2 3.84 2796.4 - 918126 - - - -4.0575 - 4.433 0.651 - 542.1 1 2 0 -0.0099 24 0 0 0 1.58E+07 1.45E+06 - - - 9.2538 0.9999 221125_WJC_METTL3_EV_vs_WT_F07.16480.16480.4 1.80E-07 17/102 K.NK[136.11]PIVNIDPQTAELNHLK[136.11].Q sp|O95239|KIF4A_HUMAN 1 2059.1397 0.42 103052 16480 4 2059.13978 515.7922 Chromosome-associated kinesin KIF4A OS=Homo sapiens OX=9606 GN=KIF4A PE=1 SV=3 6.75 2796.5 - 589488 - - - 0.0442 - 3.305 0.425 - 222.4 1 2 0 0.0001 18 0 0 0 6.23E+06 1.48E+07 - - - 3.3347 1 221125_WJC_METTL3_EV_vs_WT_F07.16484.16484.3 9.10E-08 17/52 R.ADATNVNNWHWTER.D "sp|O95433|AHSA1_HUMAN,tr|G3V3W9|G3V3W9_HUMAN" 2 1712.7655 1.22 103054 16484 3 1712.765049 571.9291 Activator of 90 kDa heat shock protein ATPase homolog 1 OS=Homo sapiens OX=9606 GN=AHSA1 PE=1 SV=1 5.32 2797 - 2.22E+06 - - - -0.2814 - 3.013 0.555 - 532.4 1 2 0 -0.0005 14 0 0 0 4.98E+07 4.07E+07 - - - 7.6587 1 221125_WJC_METTL3_EV_vs_WT_F07.16492.16492.3 1.05E-05 16/56 K.NR[166.11]PTSISWDGLDSGK[136.11].L sp|P30086|PEBP1_HUMAN 1 1649.8128 1.53 103060 16492 3 1649.812655 550.9449 Phosphatidylethanolamine-binding protein 1 OS=Homo sapiens OX=9606 GN=PEBP1 PE=1 SV=3 5.96 2798.1 - 1.49E+06 - - - -0.0994 - 2.783 0.555 - 358.2 1 2 0 -0.0002 15 0 0 0 3.74E+07 2.45E+07 - - - 7.3984 0.9999 221125_WJC_METTL3_EV_vs_WT_F07.16494.16494.4 1.66E-05 15/96 R.SNAYHFPDEPYKDGYIR.N "sp|Q9NUQ7|UFSP2_HUMAN,tr|D6RGX2|D6RGX2_HUMAN,tr|H0YA18|H0YA18_HUMAN" 3 2070.9436 28.92 103062 16494 4 2070.945491 518.7432 Ufm1-specific protease 2 OS=Homo sapiens OX=9606 GN=UFSP2 PE=1 SV=3 5.36 2798.2 - 2.79E+06 - - - 0.9348 - 3.076 0.552 - 202.3 1 2 1 0.0019 17 0 0 0 7.90E+07 2.73E+06 - - - 4.4202 1 221125_WJC_METTL3_EV_vs_WT_F07.16495.16495.3 3.40E-06 13/52 R.ADATNVNNWHWTER[166.11].D "sp|O95433|AHSA1_HUMAN,tr|G3V3W9|G3V3W9_HUMAN" 2 1722.7738 1.25 103063 16495 3 1722.772747 575.2652 Activator of 90 kDa heat shock protein ATPase homolog 1 OS=Homo sapiens OX=9606 GN=AHSA1 PE=1 SV=1 5.32 2798.3 - 2.21E+06 - - - -0.6118 - 2.964 0.491 - 354.9 1 2 0 -0.0011 14 0 0 0 4.97E+07 3.99E+07 - - - 6.9014 1 221125_WJC_METTL3_EV_vs_WT_F07.16496.16496.3 3.64E-15 22/100 K.GPPDFSSDEER[166.11]EPTPVLGSGAAAAGR[166.11].S "sp|P42166|LAP2A_HUMAN,sp|P42167|LAP2B_HUMAN,tr|G5E972|G5E972_HUMAN" 3 2589.221 0.66 103064 16496 3 2589.221915 864.0809 "Lamina-associated polypeptide 2, isoform alpha OS=Homo sapiens OX=9606 GN=TMPO PE=1 SV=2" 4.18 2798.4 - 1.27E+06 - - - 0.348 - 4.127 0.724 - 226 1 2 1 0.0009 26 0 0 0 1.05E+07 1.60E+07 - - - 9.8729 0.8993 221125_WJC_METTL3_EV_vs_WT_F07.16498.16498.2 0.567 13/18 L.PPLDPEEIRK.R "sp|Q8IY67|RAVR1_HUMAN,tr|K7EKR9|K7EKR9_HUMAN,tr|E9PAU2|E9PAU2_HUMAN,tr|A0A087WZ13|A0A087WZ13_HUMAN" 4 1192.6452 0.94 103066 16498 2 1192.641861 597.3299 Ribonucleoprotein PTB-binding 1 OS=Homo sapiens OX=9606 GN=RAVER1 PE=1 SV=1 4.68 2798.7 - 818543 - - - -2.7896 - 1.858 0.309 - 537.7 1 1 0 -0.0033 10 0 0 0 9.51E+07 1.01E+08 - - - 3.0514 1 221125_WJC_METTL3_EV_vs_WT_F07.16500.16500.3 7.53E-13 18/80 R.SAGVQC[160.03]FGPTAEAAQLESSK[136.11]R[166.11].F "sp|P22102|PUR2_HUMAN,tr|F8WD69|F8WD69_HUMAN,tr|C9JKQ7|C9JKQ7_HUMAN,tr|C9JZG2|C9JZG2_HUMAN,tr|C9JTV6|C9JTV6_HUMAN,tr|C9JBJ1|C9JBJ1_HUMAN" 6 2211.0709 0.86 103068 16500 3 2211.077041 738.0309 Trifunctional purine biosynthetic protein adenosine-3 OS=Homo sapiens OX=9606 GN=GART PE=1 SV=1 5.86 2799 - 450569 - - - 2.7769 - 4.059 0.649 - 267.6 1 2 0 0.0061 21 0 0 0 3.06E+07 3.54E+07 - - - 9.1327 0.996 221125_WJC_METTL3_EV_vs_WT_F07.16501.16501.3 0.0699 Aug-44 R.LSVEADINGLRR.V "sp|Q04695|K1C17_HUMAN,tr|F5GWP8|F5GWP8_HUMAN" 2 1341.7365 999 103069 16501 3 1341.738129 448.2528 "Keratin, type I cytoskeletal 17 OS=Homo sapiens OX=9606 GN=KRT17 PE=1 SV=2" 6.07 2799.1 - 446347 - - - 1.2424 - 1.707 0.224 - 141.3 1 2 0 0.0017 12 0 0 0 6.62E+06 0.00E+00 - - - 2.5191 1 221125_WJC_METTL3_EV_vs_WT_F07.16502.16502.4 1.72E-05 14/90 K.YAEQLPVAQIIHQKPK.L "sp|Q92643|GPI8_HUMAN,tr|B1AK81|B1AK81_HUMAN" 2 1862.0414 1.31 103070 16502 4 1862.039232 466.5176 GPI-anchor transamidase OS=Homo sapiens OX=9606 GN=PIGK PE=1 SV=2 8.51 2799.2 - 310574 - - - -1.174 - 3.13 0.551 - 147.4 1 2 0 -0.0022 16 0 0 0 2.38E+06 1.82E+06 - - - 4.4232 1 221125_WJC_METTL3_EV_vs_WT_F07.16506.16506.3 1.87E-08 19/72 R.GLLQDDAHPTLVTYADHSK[136.11].L "sp|Q86U44|MTA70_HUMAN,tr|F5H6D8|F5H6D8_HUMAN,tr|H0YFV6|H0YFV6_HUMAN,tr|B4DTN4|B4DTN4_HUMAN" 4 2088.0367 0.02 103072 16506 3 2088.036029 697.0195 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 5.13 2799.7 - 3.16E+07 - - - -0.3372 - 3.528 0.646 - 377.4 1 2 0 -0.0007 19 0 0 0 1.57E+09 9.89E+10 - - - 8.8394 1 221125_WJC_METTL3_EV_vs_WT_F07.16509.16509.3 3.21E-08 14/56 R.DTSFEQHVLWHTGGK[136.11].G "sp|P49327|FAS_HUMAN,tr|A0A0U1RQF0|A0A0U1RQF0_HUMAN" 2 1748.8362 0.53 103075 16509 3 1748.836656 583.9527 Fatty acid synthase OS=Homo sapiens OX=9606 GN=FASN PE=1 SV=3 5.99 2800 - 1.13E+06 - - - 0.2705 - 2.679 0.593 - 272.8 1 2 0 0.0005 15 0 0 0 1.48E+07 2.81E+07 - - - 7.7226 1 221125_WJC_METTL3_EV_vs_WT_F07.16510.16510.4 1.15E-10 20/84 R.DTSFEQHVLWHTGGK[136.11].G "sp|P49327|FAS_HUMAN,tr|A0A0U1RQF0|A0A0U1RQF0_HUMAN" 2 1748.8362 0.61 103076 16510 4 1748.836757 438.2163 Fatty acid synthase OS=Homo sapiens OX=9606 GN=FASN PE=1 SV=3 5.99 2800.1 - 876047 - - - 0.3282 - 3.269 0.602 - 318.6 1 2 0 0.0006 15 0 0 0 1.28E+07 2.12E+07 - - - 4.8895 1 221125_WJC_METTL3_EV_vs_WT_F07.16511.16511.3 1.52E-11 17/64 K.HC[160.03]ASQYSELLETTETPK.R "sp|Q9H0E9|BRD8_HUMAN,tr|B5MCW3|B5MCW3_HUMAN,tr|H7C179|H7C179_HUMAN,tr|H7C128|H7C128_HUMAN,tr|H7C127|H7C127_HUMAN,tr|F8WBH2|F8WBH2_HUMAN" 6 1992.9099 1.01 103077 16511 3 1992.916578 665.3106 Bromodomain-containing protein 8 OS=Homo sapiens OX=9606 GN=BRD8 PE=1 SV=2 4.75 2800.2 - 584078 - - - 3.3649 - 3.669 0.663 - 438.7 1 2 0 0.0067 17 0 0 0 6.06E+06 6.01E+06 - - - 9.2139 1 221125_WJC_METTL3_EV_vs_WT_F07.16512.16512.4 8.87E-10 20/96 K.IDSFHITGLPDNSEK[136.11]PR[166.11].L sp|Q96RL7|VP13A_HUMAN 1 1942.9868 3.75 103078 16512 4 1942.986115 486.754 Vacuolar protein sorting-associated protein 13A OS=Homo sapiens OX=9606 GN=VPS13A PE=1 SV=2 5.38 2800.4 - 542640 - - - -0.332 - 4.206 0.566 - 334.3 1 2 0 -0.0006 17 0 0 0 2.61E+07 6.96E+06 - - - 4.651 1 221125_WJC_METTL3_EV_vs_WT_F07.16513.16513.3 0.00989 14/72 K.SSSSYHTWNTGTEGPFVER[166.11].V sp|Q8TEQ6|GEMI5_HUMAN 1 2150.9533 26.13 103079 16513 3 2150.952828 717.9917 Gem-associated protein 5 OS=Homo sapiens OX=9606 GN=GEMIN5 PE=1 SV=3 5.38 2800.5 - 516994 - - - -0.2106 - 2.743 0.444 - 228.3 1 2 0 -0.0005 19 0 0 0 4.67E+09 1.79E+08 - - - 5.9691 0.9998 221125_WJC_METTL3_EV_vs_WT_F07.16514.16514.4 0.000173 16/126 K.AQEPVKGPVSTKPGSC[160.03]PIILIR.C sp|P19957|ELAF_HUMAN 1 2346.3093 999 103080 16514 4 2346.311122 587.5846 Elafin OS=Homo sapiens OX=9606 GN=PI3 PE=1 SV=3 9.32 2800.6 - 507995 - - - 0.7608 - 2.921 0.473 - 153.6 1 2 1 0.0018 22 0 0 0 1.47E+07 0.00E+00 - - - 3.6932 0.9943 221125_WJC_METTL3_EV_vs_WT_F07.16515.16515.2 2.67E-05 Sep-36 R.GLLQDDAHPTLVTYADHSK[136.11].L "sp|Q86U44|MTA70_HUMAN,tr|F5H6D8|F5H6D8_HUMAN,tr|H0YFV6|H0YFV6_HUMAN,tr|B4DTN4|B4DTN4_HUMAN" 4 2088.0367 0.01 103081 16515 2 2089.040818 1045.0256 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 5.13 2800.8 - 351503 - - - 480.8752 - 2.159 0.553 - 166.9 1 2 0 1.0041 19 0 0 0 6.17E+07 6.25E+09 - - - 4.7024 1 221125_WJC_METTL3_EV_vs_WT_F07.16519.16519.3 5.22E-18 25/100 K.GPPDFSSDEEREPTPVLGSGAAAAGR.S "sp|P42166|LAP2A_HUMAN,sp|P42167|LAP2B_HUMAN,tr|G5E972|G5E972_HUMAN" 3 2569.2045 1.21 103083 16519 3 2569.205175 857.4088 "Lamina-associated polypeptide 2, isoform alpha OS=Homo sapiens OX=9606 GN=TMPO PE=1 SV=2" 4.18 2801.3 - 2.78E+06 - - - 0.2728 - 4.337 0.755 - 362.9 1 2 1 0.0007 26 0 0 0 7.51E+07 6.22E+07 - - - 10.3328 1 221125_WJC_METTL3_EV_vs_WT_F07.16520.16520.3 8.76E-06 13/56 R.DTSFEQHVLWHTGGK.G "sp|P49327|FAS_HUMAN,tr|A0A0U1RQF0|A0A0U1RQF0_HUMAN" 2 1740.822 0.53 103084 16520 3 1740.823749 581.2813 Fatty acid synthase OS=Homo sapiens OX=9606 GN=FASN PE=1 SV=3 5.99 2801.5 - 922059 - - - 1.0145 - 2.616 0.517 - 226.3 1 2 0 0.0018 15 0 0 0 1.48E+07 2.76E+07 - - - 6.8128 1 221125_WJC_METTL3_EV_vs_WT_F07.16521.16521.3 3.45E-08 15/64 K.KQEETAVLEEDSADWEK.E sp|Q96A49|SYAP1_HUMAN 1 2005.9116 1.4 103085 16521 3 2005.913105 669.6445 Synapse-associated protein 1 OS=Homo sapiens OX=9606 GN=SYAP1 PE=1 SV=1 4 2801.6 - 1.03E+06 - - - 0.7274 - 3.142 0.606 - 309.6 1 2 0 0.0015 17 0 0 0 2.51E+08 1.79E+08 - - - 8.1882 1 221125_WJC_METTL3_EV_vs_WT_F07.16522.16522.3 0.000171 19/72 R.HGSGPNIILTGDSSPGFSK[136.11].E "sp|Q53ET0|CRTC2_HUMAN,tr|Q5T4K5|Q5T4K5_HUMAN" 2 1877.9363 1.47 103086 16522 3 1877.936769 626.986 CREB-regulated transcription coactivator 2 OS=Homo sapiens OX=9606 GN=CRTC2 PE=1 SV=2 6.74 2801.7 - 885572 - - - 0.2545 - 3.711 0.507 - 430.9 1 2 0 0.0005 19 0 0 0 3.09E+07 2.10E+07 - - - 7.414 0.9606 221125_WJC_METTL3_EV_vs_WT_F07.16523.16523.3 0.0032 14/76 K.SSEFASIPANSSR[166.11]PLSNISK[136.11].S sp|Q9NYZ3|GTSE1_HUMAN 1 2109.0821 2.8 103087 16523 3 2109.085386 704.0346 G2 and S phase-expressed protein 1 OS=Homo sapiens OX=9606 GN=GTSE1 PE=1 SV=3 8.46 2801.8 - 550014 - - - 1.55 - 2.002 0.089 - 157.6 1 2 0 0.0033 20 0 0 0 3.16E+07 1.13E+07 - - - 1.2154 0.769 221125_WJC_METTL3_EV_vs_WT_F07.16525.16525.4 0.0832 Oct-90 R.EGSFLWIGSGVC[160.03]MEMA.S tr|E9PIN3|E9PIN3_HUMAN 1 1772.7572 - 103089 16525 4 1772.756532 444.1966 Nuclear RNA export factor 1 (Fragment) OS=Homo sapiens OX=9606 GN=NXF1 PE=1 SV=1 3.8 2802.1 - 430752 - - - -0.3768 - 1.379 0.269 - 32.6 1 1 0 -0.0007 16 0 0 0 - - - - - 1.6804 0.9493 221125_WJC_METTL3_EV_vs_WT_F07.16528.16528.4 0.00307 16/114 R.EAIVNSC[160.03]VFVHQTLHQANAR[166.11].L "sp|Q14204|DYHC1_HUMAN,tr|A0A7P0T8N2|A0A7P0T8N2_HUMAN,tr|A0A7P0T9C4|A0A7P0T9C4_HUMAN,tr|A0A7P0TBJ7|A0A7P0TBJ7_HUMAN,tr|A0A7P0T9K2|A0A7P0T9K2_HUMAN,tr|A0A2R8Y706|A0A2R8Y706_HUMAN,tr|A0A7P0T916|A0A7P0T916_HUMAN,tr|A0A7P0TB75|A0A7P0TB75_HUMAN,tr|A0A7P0T8W5|A0A7P0T8W5_HUMAN,tr|A0A7P0TAF3|A0A7P0TAF3_HUMAN,tr|A0A7P0T9F1|A0A7P0T9F1_HUMAN,tr|A0A7P0TAW9|A0A7P0TAW9_HUMAN,tr|A0A7P0TA13|A0A7P0TA13_HUMAN,tr|A0A7P0T7V5|A0A7P0T7V5_HUMAN,tr|A0A7P0T9R4|A0A7P0T9R4_HUMAN,tr|A0A2R8Y5T0|A0A2R8Y5T0_HUMAN,tr|A0A2R8YFZ7|A0A2R8YFZ7_HUMAN,tr|A0A7P0T825|A0A7P0T825_HUMAN,tr|A0A2R8Y6H2|A0A2R8Y6H2_HUMAN,tr|A0A7P0TAM4|A0A7P0TAM4_HUMAN" 20 2303.1469 0.52 103091 16528 4 2304.151181 576.794 Cytoplasmic dynein 1 heavy chain 1 OS=Homo sapiens OX=9606 GN=DYNC1H1 PE=1 SV=5 7 2802.4 - 825642 - - - 436.0677 - 2.689 0.28 - 117.4 1 2 0 1.0043 20 0 0 0 5.06E+06 9.76E+06 - - - 1.7156 1 221125_WJC_METTL3_EV_vs_WT_F07.16529.16529.3 1.81E-07 19/64 K.K[136.11]QEETAVLEEDSADWEK[136.11].E sp|Q96A49|SYAP1_HUMAN 1 2021.94 1.4 103092 16529 3 2021.939252 674.9873 Synapse-associated protein 1 OS=Homo sapiens OX=9606 GN=SYAP1 PE=1 SV=1 4 2802.5 - 1.96E+06 - - - -0.3927 - 3.442 0.559 - 513.9 1 2 0 -0.0008 17 0 0 0 2.51E+08 1.79E+08 - - - 7.8947 0.9737 221125_WJC_METTL3_EV_vs_WT_F07.16530.16530.3 0.0998 Dec-72 K.SSSSYHTWNTGTEGPFVER.V sp|Q8TEQ6|GEMI5_HUMAN 1 2140.945 26.34 103093 16530 3 2140.952897 714.6556 Gem-associated protein 5 OS=Homo sapiens OX=9606 GN=GEMIN5 PE=1 SV=3 5.38 2802.6 - 1.22E+06 - - - 3.6834 - 1.885 0.201 - 73.9 1 2 0 0.0079 19 0 0 0 4.68E+09 1.78E+08 - - - 2.3362 1 221125_WJC_METTL3_EV_vs_WT_F07.16531.16531.3 6.71E-07 26/96 T.GSSAQEEASGVALGEAPDHSYESLR.V "sp|Q13011|ECH1_HUMAN,tr|M0QYT0|M0QYT0_HUMAN,tr|M0QZW4|M0QZW4_HUMAN,tr|M0R248|M0R248_HUMAN" 4 2546.1521 13.18 103094 16531 3 2546.149612 849.7246 "Delta(3,5)-Delta(2,4)-dienoyl-CoA isomerase, mitochondrial OS=Homo sapiens OX=9606 GN=ECH1 PE=1 SV=2" 4.25 2802.8 - 955234 - - - -0.9787 - 4.839 0.628 - 766 1 1 0 -0.0025 25 0 0 0 1.31E+07 9.96E+05 - - - 9.1683 1 221125_WJC_METTL3_EV_vs_WT_F07.16534.16534.3 3.62E-09 16/56 K.HIANYISGIQTIGHR.V sp|Q15393|SF3B3_HUMAN 1 1678.8903 0.71 103097 16534 3 1678.891 560.6374 Splicing factor 3B subunit 3 OS=Homo sapiens OX=9606 GN=SF3B3 PE=1 SV=4 8.76 2803.1 - 590787 - - - 0.3949 - 3.095 0.549 - 380.6 1 2 0 0.0007 15 0 0 0 2.33E+08 3.29E+08 - - - 7.6087 0.9999 221125_WJC_METTL3_EV_vs_WT_F07.16535.16535.3 1.15E-06 Dec-44 R.STGHMFHIDFGK.F sp|O00443|P3C2A_HUMAN 1 1375.6343 1.34 103098 16535 3 1375.636584 459.552 Phosphatidylinositol 4-phosphate 3-kinase C2 domain-containing subunit alpha OS=Homo sapiens OX=9606 GN=PIK3C2A PE=1 SV=2 6.66 2803.3 - 397916 - - - 1.656 - 2.145 0.5 - 157.4 1 2 0 0.0023 12 0 0 0 8.95E+06 6.66E+06 - - - 6.2292 0.9997 221125_WJC_METTL3_EV_vs_WT_F07.16536.16536.3 5.44E-05 Sep-44 R.STGHMFHIDFGK[136.11].F sp|O00443|P3C2A_HUMAN 1 1383.6485 1.37 103099 16536 3 1383.644684 462.2234 Phosphatidylinositol 4-phosphate 3-kinase C2 domain-containing subunit alpha OS=Homo sapiens OX=9606 GN=PIK3C2A PE=1 SV=2 6.66 2803.4 - 308152 - - - -2.7623 - 1.592 0.486 - 84.3 1 2 0 -0.0038 12 0 0 0 8.95E+06 6.53E+06 - - - 5.2462 0.9999 221125_WJC_METTL3_EV_vs_WT_F07.16538.16538.2 0.0375 15/36 R.VIHLSNLPHSGYSDSAVLK[136.11].L "sp|P43243|MATR3_HUMAN,tr|B3KM87|B3KM87_HUMAN,tr|A8MXP9|A8MXP9_HUMAN,tr|D6RBK5|D6RBK5_HUMAN,tr|A0A0R4J2E8|A0A0R4J2E8_HUMAN,tr|H0Y8T4|H0Y8T4_HUMAN,tr|D6REM6|D6REM6_HUMAN" 7 2044.0833 1.46 103101 16538 2 2044.083015 1023.0489 Matrin-3 OS=Homo sapiens OX=9606 GN=MATR3 PE=1 SV=2 6.89 2803.7 - 242927 - - - -0.1345 - 3.029 0.515 - 450.9 1 2 0 -0.0003 19 0 0 0 6.24E+06 4.28E+06 - - - 5.5693 1 221125_WJC_METTL3_EV_vs_WT_F07.16541.16541.3 1.94E-07 20/72 R.HGSGPNIILTGDSSPGFSK.E "sp|Q53ET0|CRTC2_HUMAN,tr|Q5T4K5|Q5T4K5_HUMAN" 2 1869.9221 1.48 103102 16541 3 1869.92321 624.3146 CREB-regulated transcription coactivator 2 OS=Homo sapiens OX=9606 GN=CRTC2 PE=1 SV=2 6.74 2804.1 - 1.68E+06 - - - 0.5984 - 3.706 0.646 - 469.4 1 2 0 0.0011 19 0 0 0 3.10E+07 2.10E+07 - - - 8.9602 0.9999 221125_WJC_METTL3_EV_vs_WT_F07.16542.16542.2 7.56E-10 16/36 R.VIHLSNLPHSGYSDSAVLK.L "sp|P43243|MATR3_HUMAN,tr|B3KM87|B3KM87_HUMAN,tr|A8MXP9|A8MXP9_HUMAN,tr|D6RBK5|D6RBK5_HUMAN,tr|A0A0R4J2E8|A0A0R4J2E8_HUMAN,tr|H0Y8T4|H0Y8T4_HUMAN,tr|D6REM6|D6REM6_HUMAN" 7 2036.0691 1.46 103103 16542 2 2036.071128 1019.0418 Matrin-3 OS=Homo sapiens OX=9606 GN=MATR3 PE=1 SV=2 6.89 2804.2 - 448263 - - - 1.0009 - 3.367 0.49 - 556 1 2 0 0.002 19 0 0 0 6.24E+06 4.28E+06 - - - 5.6442 1 221125_WJC_METTL3_EV_vs_WT_F07.16548.16548.3 2.39E-06 13/96 K.LVQDVANNTNEEAGDGTTTATVLAR.S "sp|P10809|CH60_HUMAN,tr|C9JL25|C9JL25_HUMAN,tr|A0A7I2V2X6|A0A7I2V2X6_HUMAN,tr|A0A7I2YQK6|A0A7I2YQK6_HUMAN,tr|A0A7I2V599|A0A7I2V599_HUMAN,tr|E7EXB4|E7EXB4_HUMAN,tr|A0A7I2YQ71|A0A7I2YQ71_HUMAN,tr|E7ESH4|E7ESH4_HUMAN,tr|A0A7I2V5M1|A0A7I2V5M1_HUMAN,tr|A0A7I2V5K3|A0A7I2V5K3_HUMAN,tr|A0A7I2V369|A0A7I2V369_HUMAN" 11 2559.2413 999 103109 16548 3 2559.248153 854.0877 "60 kDa heat shock protein, mitochondrial OS=Homo sapiens OX=9606 GN=HSPD1 PE=1 SV=2" 3.92 2805 - 388344 - - - 2.6961 - 3.033 0.582 - 182.6 1 2 0 0.0069 25 0 0 0 7.24E+06 0.00E+00 - - - 7.5795 1 221125_WJC_METTL3_EV_vs_WT_F07.16551.16551.3 1.15E-06 14/68 R.NLTHNPPSDFSFQNMNSK.R sp|Q9Y2H1|ST38L_HUMAN 1 2076.9323 3.74 103110 16551 3 2076.935444 693.3181 Serine\threonine-protein kinase 38-like OS=Homo sapiens OX=9606 GN=STK38L PE=1 SV=3 6.74 2805.4 - 2.05E+06 - - - 1.4955 - 2.76 0.544 - 212.3 1 2 0 0.0031 18 0 0 0 1.90E+08 5.09E+07 - - - 7.1322 1 221125_WJC_METTL3_EV_vs_WT_F07.16554.16554.2 3.87E-12 20/32 K.K[136.11]QEETAVLEEDSADWEK[136.11].E sp|Q96A49|SYAP1_HUMAN 1 2021.94 1.56 103113 16554 2 2021.938347 1011.9773 Synapse-associated protein 1 OS=Homo sapiens OX=9606 GN=SYAP1 PE=1 SV=1 4 2805.8 - 268175 - - - -0.8403 - 4.195 0.748 - 1497.1 1 2 0 -0.0017 17 0 0 0 9.56E+06 6.12E+06 - - - 8.0905 1 221125_WJC_METTL3_EV_vs_WT_F07.16561.16561.3 8.42E-08 16/56 R.GPSLNPVLDYDHGSR[166.11].S "sp|P43243|MATR3_HUMAN,tr|A8MXP9|A8MXP9_HUMAN,tr|D6R991|D6R991_HUMAN,tr|A0A0R4J2E8|A0A0R4J2E8_HUMAN,tr|D6REM6|D6REM6_HUMAN" 5 1635.7881 1.37 103118 16561 3 1635.788736 546.27 Matrin-3 OS=Homo sapiens OX=9606 GN=MATR3 PE=1 SV=2 5.21 2806.6 - 835437 - - - 0.4169 - 3.186 0.539 - 409.4 1 2 0 0.0007 15 0 0 0 2.83E+07 2.06E+07 - - - 7.5728 1 221125_WJC_METTL3_EV_vs_WT_F07.16563.16563.3 2.51E-10 28/100 R.R[166.11]AAAASAAEAGIATTGTEDSDDALLK[136.11].M "sp|P55036|PSMD4_HUMAN,tr|H0Y3Y9|H0Y3Y9_HUMAN" 2 2493.2314 1.06 103120 16563 3 2494.23082 832.0844 26S proteasome non-ATPase regulatory subunit 4 OS=Homo sapiens OX=9606 GN=PSMD4 PE=1 SV=1 4.11 2806.9 - 435684 - - - 400.8693 - 5.249 0.683 - 790.4 1 2 0 0.9995 26 0 0 0 2.92E+07 2.75E+07 - - - 9.6925 1 221125_WJC_METTL3_EV_vs_WT_F07.16567.16567.3 8.03E-10 20/68 R.KDLLVENVPYC[160.03]DAPTQKQ.- "sp|Q5U5X0|LYRM7_HUMAN,tr|D6R994|D6R994_HUMAN" 2 2117.0463 1.15 103122 16567 3 2117.048972 706.6894 Complex III assembly factor LYRM7 OS=Homo sapiens OX=9606 GN=LYRM7 PE=1 SV=1 4.56 2807.4 - 869914 - - - 1.2593 - 3.745 0.657 - 682.2 1 2 0 0.0027 18 0 0 0 1.61E+07 1.40E+07 - - - 9.1521 1 221125_WJC_METTL3_EV_vs_WT_F07.16570.16570.2 1.57E-11 26/32 K.KQEETAVLEEDSADWEK.E sp|Q96A49|SYAP1_HUMAN 1 2005.9116 1.56 103125 16570 2 2005.909858 1003.9631 Synapse-associated protein 1 OS=Homo sapiens OX=9606 GN=SYAP1 PE=1 SV=1 4 2807.8 - 484466 - - - -0.8914 - 4.848 0.759 - 3084.6 1 2 0 -0.0018 17 0 0 0 9.56E+06 6.12E+06 - - - 8.5274 0.8126 221125_WJC_METTL3_EV_vs_WT_F07.16571.16571.4 0.0314 Oct-90 F.AYLEDLHSEFDEQHGK[136.11].K sp|O75396|SC22B_HUMAN 1 1924.8683 1.46 103126 16571 4 1924.867555 482.2243 Vesicle-trafficking protein SEC22b OS=Homo sapiens OX=9606 GN=SEC22B PE=1 SV=5 4.49 2807.9 - 308204 - - - -0.372 - 1.482 0.278 - 35.2 1 1 0 -0.0007 16 0 0 0 3.90E+06 2.66E+06 - - - 1.7841 0.9999 221125_WJC_METTL3_EV_vs_WT_F07.16573.16573.4 1.42E-06 14/108 R.VIHLSNLPHSGYSDSAVLK.L "sp|P43243|MATR3_HUMAN,tr|B3KM87|B3KM87_HUMAN,tr|A8MXP9|A8MXP9_HUMAN,tr|D6RBK5|D6RBK5_HUMAN,tr|A0A0R4J2E8|A0A0R4J2E8_HUMAN,tr|H0Y8T4|H0Y8T4_HUMAN,tr|D6REM6|D6REM6_HUMAN" 7 2036.0691 0.91 103127 16573 4 2036.072627 510.0245 Matrin-3 OS=Homo sapiens OX=9606 GN=MATR3 PE=1 SV=2 6.89 2808.1 - 6.21E+07 - - - 1.7372 - 2.905 0.412 - 167.8 1 2 0 0.0035 19 0 0 0 1.15E+09 1.26E+09 - - - 3.1718 1 221125_WJC_METTL3_EV_vs_WT_F07.16576.16576.3 2.59E-12 27/100 R.RAAAASAAEAGIATTGTEDSDDALLK.M "sp|P55036|PSMD4_HUMAN,tr|H0Y3Y9|H0Y3Y9_HUMAN" 2 2475.2089 1.06 103129 16576 3 2475.208781 826.0769 26S proteasome non-ATPase regulatory subunit 4 OS=Homo sapiens OX=9606 GN=PSMD4 PE=1 SV=1 4.11 2808.5 - 972468 - - - -0.044 - 5.114 0.678 - 709.6 1 2 0 -0.0001 26 0 0 0 2.89E+07 2.73E+07 - - - 9.8536 1 221125_WJC_METTL3_EV_vs_WT_F07.16577.16577.3 1.15E-09 18/68 R.K[136.11]DLLVENVPYC[160.03]DAPTQK[136.11]Q.- "sp|Q5U5X0|LYRM7_HUMAN,tr|D6R994|D6R994_HUMAN" 2 2133.0747 1.15 103130 16577 3 2133.07247 712.0322 Complex III assembly factor LYRM7 OS=Homo sapiens OX=9606 GN=LYRM7 PE=1 SV=1 4.56 2808.6 - 998756 - - - -1.0483 - 3.362 0.635 - 498.1 1 2 0 -0.0022 18 0 0 0 1.61E+07 1.40E+07 - - - 8.6383 1 221125_WJC_METTL3_EV_vs_WT_F07.16581.16581.3 1.11E-10 20/56 R.RTDIFGVEETAIGKK.L sp|Q15459|SF3A1_HUMAN 1 1662.8941 0.94 103134 16581 3 1662.894933 555.3053 Splicing factor 3A subunit 1 OS=Homo sapiens OX=9606 GN=SF3A1 PE=1 SV=1 6.18 2809.1 - 461180 - - - 0.51 - 3.288 0.592 - 642.9 1 2 0 0.0008 15 0 0 0 1.82E+07 1.94E+07 - - - 8.2459 1 221125_WJC_METTL3_EV_vs_WT_F07.16582.16582.4 2.38E-05 17/90 K.YAEQLPVAQIIHQK[136.11]PK[136.11].L "sp|Q92643|GPI8_HUMAN,tr|B1AK81|B1AK81_HUMAN" 2 1878.0698 1.15 103135 16582 4 1878.073132 470.5247 GPI-anchor transamidase OS=Homo sapiens OX=9606 GN=PIGK PE=1 SV=2 8.51 2809.2 - 438014 - - - 1.7646 - 3.12 0.519 - 229.7 1 2 0 0.0033 16 0 0 0 1.43E+07 1.24E+07 - - - 4.1433 1 221125_WJC_METTL3_EV_vs_WT_F07.16591.16591.3 1.26E-09 15/56 K.AADHLKPFLDDSTLR.F sp|O43395|PRPF3_HUMAN 1 1697.8737 3.41 103142 16591 3 1697.876527 566.9652 U4\U6 small nuclear ribonucleoprotein Prp3 OS=Homo sapiens OX=9606 GN=PRPF3 PE=1 SV=2 5.3 2810.2 - 1.03E+06 - - - 1.6744 - 2.853 0.54 - 327.2 1 2 0 0.0028 15 0 0 0 2.66E+07 7.79E+06 - - - 7.2953 1 221125_WJC_METTL3_EV_vs_WT_F07.16592.16592.4 2.33E-08 18/84 K.AADHLKPFLDDSTLR.F sp|O43395|PRPF3_HUMAN 1 1697.8737 2.58 103143 16592 4 1697.875845 425.4757 U4\U6 small nuclear ribonucleoprotein Prp3 OS=Homo sapiens OX=9606 GN=PRPF3 PE=1 SV=2 5.3 2810.4 - 797898 - - - 1.2728 - 3.111 0.527 - 293.5 1 2 0 0.0022 15 0 0 0 1.26E+07 4.87E+06 - - - 4.2185 1 221125_WJC_METTL3_EV_vs_WT_F07.16595.16595.4 1.27E-07 16/84 R.R[166.11]TDIFGVEETAIGK[136.11]K[136.11].L sp|Q15459|SF3A1_HUMAN 1 1688.9308 0.78 103146 16595 4 1688.930693 423.24 Splicing factor 3A subunit 1 OS=Homo sapiens OX=9606 GN=SF3A1 PE=1 SV=1 6.18 2810.7 - 365474 - - - -0.0367 - 2.518 0.555 - 155.3 1 2 0 -0.0001 15 0 0 0 6.44E+06 8.27E+06 - - - 4.3871 0.9999 221125_WJC_METTL3_EV_vs_WT_F07.16597.16597.4 0.000134 13/84 R.RTDIFGVEETAIGKK.L sp|Q15459|SF3A1_HUMAN 1 1662.8941 0.78 103148 16597 4 1662.893064 416.7308 Splicing factor 3A subunit 1 OS=Homo sapiens OX=9606 GN=SF3A1 PE=1 SV=1 6.18 2811 - 299743 - - - -0.614 - 2.054 0.412 - 96.3 1 2 0 -0.001 15 0 0 0 6.44E+06 8.27E+06 - - - 3.0693 1 221125_WJC_METTL3_EV_vs_WT_F07.16603.16603.3 4.47E-11 19/72 R.DSAWGTSDHSVSQPIMVQR.R "sp|Q14671|PUM1_HUMAN,tr|Q5T1Z8|Q5T1Z8_HUMAN,tr|H0YEH2|H0YEH2_HUMAN,tr|Q5T1Z4|Q5T1Z4_HUMAN" 4 2099.9695 2.14 103152 16603 3 2099.963789 700.9971 Pumilio homolog 1 OS=Homo sapiens OX=9606 GN=PUM1 PE=1 SV=3 5.21 2811.7 - 2.51E+06 - - - -2.6967 - 3.645 0.721 - 372.3 1 2 0 -0.0057 19 0 0 0 4.38E+08 2.04E+08 - - - 9.7544 1 221125_WJC_METTL3_EV_vs_WT_F07.16605.16605.3 3.10E-07 18/72 R.DSAWGTSDHSVSQPIMVQR[166.11].R "sp|Q14671|PUM1_HUMAN,tr|Q5T1Z8|Q5T1Z8_HUMAN,tr|H0YEH2|H0YEH2_HUMAN,tr|Q5T1Z4|Q5T1Z4_HUMAN" 4 2109.9777 2.15 103154 16605 3 2109.979875 704.3332 Pumilio homolog 1 OS=Homo sapiens OX=9606 GN=PUM1 PE=1 SV=3 5.21 2811.9 - 1.58E+06 - - - 1.0204 - 3.533 0.621 - 264.4 1 2 0 0.0022 19 0 0 0 4.38E+08 2.03E+08 - - - 8.5638 1 221125_WJC_METTL3_EV_vs_WT_F07.16606.16606.3 1.20E-08 19/56 R.R[166.11]TDIFGVEETAIGK[136.11]K[136.11].L sp|Q15459|SF3A1_HUMAN 1 1688.9308 0.94 103155 16606 3 1688.935861 563.9842 Splicing factor 3A subunit 1 OS=Homo sapiens OX=9606 GN=SF3A1 PE=1 SV=1 6.18 2812 - 1.29E+06 - - - 3.0232 - 3.826 0.63 - 558 1 2 0 0.0051 15 0 0 0 1.82E+07 1.94E+07 - - - 9.0638 1 221125_WJC_METTL3_EV_vs_WT_F07.16607.16607.3 1.48E-10 24/80 R.SAGVQC[160.03]FGPTAEAAQLESSKR.F "sp|P22102|PUR2_HUMAN,tr|F8WD69|F8WD69_HUMAN,tr|C9JKQ7|C9JKQ7_HUMAN,tr|C9JZG2|C9JZG2_HUMAN,tr|C9JTV6|C9JTV6_HUMAN,tr|C9JBJ1|C9JBJ1_HUMAN" 6 2193.0484 0.87 103156 16607 3 2193.051554 732.0234 Trifunctional purine biosynthetic protein adenosine-3 OS=Homo sapiens OX=9606 GN=GART PE=1 SV=1 5.86 2812.1 - 1.29E+06 - - - 1.424 - 4.4 0.677 - 707.8 1 2 0 0.0031 21 0 0 0 3.06E+07 3.53E+07 - - - 9.6391 1 221125_WJC_METTL3_EV_vs_WT_F07.16608.16608.3 1.70E-09 15/60 K.LRETLEEYNKEFAEVK.N "sp|Q13948|CASP_HUMAN,sp|P39880|CUX1_HUMAN,tr|A0A2R8Y852|A0A2R8Y852_HUMAN,tr|A0A2R8YDI1|A0A2R8YDI1_HUMAN" 4 1997.0106 3.48 103157 16608 3 1997.01293 666.6775 Protein CASP OS=Homo sapiens OX=9606 GN=CUX1 PE=1 SV=2 4.65 2812.3 - 497809 - - - 1.1808 - 3.529 0.635 - 334 1 2 2 0.0024 16 0 0 0 9.28E+06 2.67E+06 - - - 8.8546 1 221125_WJC_METTL3_EV_vs_WT_F07.16610.16610.2 7.75E-09 Dec-32 K.IISNASC[160.03]TTNC[160.03]LAPLAK[136.11].V "sp|P04406|G3P_HUMAN,tr|E7EUT5|E7EUT5_HUMAN" 2 1840.9267 1.22 103159 16610 2 1840.934062 921.4706 Glyceraldehyde-3-phosphate dehydrogenase OS=Homo sapiens OX=9606 GN=GAPDH PE=1 SV=3 8.06 2812.5 - 220152 - - - 4.0235 - 2.76 0.644 - 278.4 1 2 0 0.0074 17 0 0 0 2.49E+06 2.04E+06 - - - 6.2912 0.9988 221125_WJC_METTL3_EV_vs_WT_F07.16613.16613.3 3.13E-08 24/88 T.SGGPK[136.11]PSTASAVPELATDPELEK[136.11].K "sp|Q86U44|MTA70_HUMAN,tr|B4E349|B4E349_HUMAN,tr|F5H6D8|F5H6D8_HUMAN,tr|H0YFV6|H0YFV6_HUMAN,tr|B4DTN4|B4DTN4_HUMAN" 5 2296.1769 0 103160 16613 3 2296.178068 766.3996 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 4.41 2812.9 - 3.78E+06 - - - 0.4991 - 3.275 0.602 - 500 1 1 0 0.0011 23 0 0 0 1.82E+05 1.06E+08 - - - 8.0344 0.9982 221125_WJC_METTL3_EV_vs_WT_F07.16616.16616.3 0.007 17/76 R.ARDAAEAR[166.11]VAELPAAC[160.03]EEAR[166.11].Q sp|Q8TF21|ANR24_HUMAN 1 2175.0606 - 103163 16616 3 2175.059716 726.0275 Ankyrin repeat domain-containing protein 24 OS=Homo sapiens OX=9606 GN=ANKRD24 PE=2 SV=2 4.59 2813.3 - 1.23E+06 - - - -0.3853 - 2.501 0.291 - 248.9 1 2 2 -0.0008 20 0 0 0 - - - - - 4.008 0.9999 221125_WJC_METTL3_EV_vs_WT_F07.16619.16619.4 3.41E-07 16/90 K.LR[166.11]ETLEEYNK[136.11]EFAEVK[136.11].N "sp|Q13948|CASP_HUMAN,sp|P39880|CUX1_HUMAN,tr|A0A2R8Y852|A0A2R8Y852_HUMAN,tr|A0A2R8YDI1|A0A2R8YDI1_HUMAN" 4 2023.0472 0.95 103166 16619 4 2023.046464 506.7691 Protein CASP OS=Homo sapiens OX=9606 GN=CUX1 PE=1 SV=2 4.65 2813.6 - 792264 - - - -0.3846 - 3.294 0.516 - 225.9 1 2 2 -0.0008 16 0 0 0 1.09E+07 1.14E+07 - - - 4.137 1 221125_WJC_METTL3_EV_vs_WT_F07.16622.16622.2 7.52E-10 18-Dec R.LVNHFVEEFK[136.11].R "sp|P0DMV8|HS71A_HUMAN,sp|P0DMV9|HS71B_HUMAN,tr|V9GZ37|V9GZ37_HUMAN,tr|A0A0G2JIW1|A0A0G2JIW1_HUMAN" 4 1268.6645 0.04 103169 16622 2 1268.666662 635.3395 Heat shock 70 kDa protein 1A OS=Homo sapiens OX=9606 GN=HSPA1A PE=1 SV=1 5.4 2814 - 546667 - - - 1.7254 - 2.765 0.611 - 516.2 1 2 0 0.0022 10 0 0 0 5.40E+05 1.40E+07 - - - 6.392 0.9911 221125_WJC_METTL3_EV_vs_WT_F07.16628.16628.3 0.00516 Aug-36 R.LVNHFVEEFK[136.11].R "sp|P0DMV8|HS71A_HUMAN,sp|P0DMV9|HS71B_HUMAN,tr|V9GZ37|V9GZ37_HUMAN,tr|A0A0G2JIW1|A0A0G2JIW1_HUMAN" 4 1268.6645 0.1 103173 16628 3 1268.663666 423.8954 Heat shock 70 kDa protein 1A OS=Homo sapiens OX=9606 GN=HSPA1A PE=1 SV=1 5.4 2814.7 - 1.65E+06 - - - -0.6361 - 1.767 0.15 - 76.9 1 2 0 -0.0008 10 0 0 0 2.55E+06 2.68E+07 - - - 1.8747 0.9999 221125_WJC_METTL3_EV_vs_WT_F07.16632.16632.3 6.51E-07 Dec-88 K.NALPPVLTTVNGQSPPEHSAPAK[136.11].V "sp|Q6PKG0|LARP1_HUMAN,tr|A0A0B4J210|A0A0B4J210_HUMAN,tr|H0YBM7|H0YBM7_HUMAN" 3 2332.2267 1.67 103177 16632 3 2332.233661 778.4162 La-related protein 1 OS=Homo sapiens OX=9606 GN=LARP1 PE=1 SV=2 6.75 2815.3 - 522415 - - - 3.0019 - 2.653 0.554 - 130.5 1 2 0 0.007 23 0 0 0 3.55E+07 2.13E+07 - - - 7.0035 0.9962 221125_WJC_METTL3_EV_vs_WT_F07.16640.16640.4 0.00174 11/108 R.VIHLSNLPHSGYSDSAVLK[136.11].L "sp|P43243|MATR3_HUMAN,tr|B3KM87|B3KM87_HUMAN,tr|A8MXP9|A8MXP9_HUMAN,tr|D6RBK5|D6RBK5_HUMAN,tr|A0A0R4J2E8|A0A0R4J2E8_HUMAN,tr|H0Y8T4|H0Y8T4_HUMAN,tr|D6REM6|D6REM6_HUMAN" 7 2044.0833 1.03 103183 16640 4 2044.085706 512.0281 Matrin-3 OS=Homo sapiens OX=9606 GN=MATR3 PE=1 SV=2 6.89 2816.2 - 470819 - - - 1.1819 - 2.145 0.234 - 97.6 1 2 0 0.0024 19 0 0 0 2.35E+06 2.27E+06 - - - 1.5202 0.9967 221125_WJC_METTL3_EV_vs_WT_F07.16651.16651.3 3.43E-07 15/64 R.FSR[166.11]EEFPTLQAAGDQDK[136.11].A sp|P48634|PRC2A_HUMAN 1 1955.9344 1.13 103192 16651 3 1956.939483 652.9854 Protein PRRC2A OS=Homo sapiens OX=9606 GN=PRRC2A PE=1 SV=3 4.32 2817.5 - 399148 - - - 513.8685 - 2.94 0.524 - 338.6 1 2 1 1.0051 17 0 0 0 1.50E+07 1.32E+07 - - - 6.8281 1 221125_WJC_METTL3_EV_vs_WT_F07.16655.16655.4 1.21E-08 17/138 K.NLEEGHSSTVAAHYNELQEVGLEK.R sp|O43148|MCES_HUMAN 1 2653.262 1.28 103194 16655 4 2653.26177 664.3228 mRNA cap guanine-N7 methyltransferase OS=Homo sapiens OX=9606 GN=RNMT PE=1 SV=1 4.62 2818.1 - 1.38E+06 - - - -0.0825 - 3.344 0.593 - 120.1 1 2 0 -0.0002 24 0 0 0 1.90E+07 1.48E+07 - - - 4.7749 1 221125_WJC_METTL3_EV_vs_WT_F07.16656.16656.3 0.000805 18/64 R.K[136.11]DLLVENVPYC[160.03]DAPTQK[136.11].Q "sp|Q5U5X0|LYRM7_HUMAN,tr|D6R994|D6R994_HUMAN" 2 2005.0161 1.78 103195 16656 3 2005.013306 669.346 Complex III assembly factor LYRM7 OS=Homo sapiens OX=9606 GN=LYRM7 PE=1 SV=1 4.56 2818.2 - 566459 - - - -1.4075 - 3.185 0.509 - 487.2 1 2 0 -0.0028 17 0 0 0 1.01E+07 5.66E+06 - - - 7.1407 0.9998 221125_WJC_METTL3_EV_vs_WT_F07.16657.16657.4 6.74E-08 23/108 R.EDLQLDKPASGVKEEWYAR.L "sp|P78347|GTF2I_HUMAN,tr|A0A494C0Q7|A0A494C0Q7_HUMAN,tr|A0A494C1K3|A0A494C1K3_HUMAN" 3 2233.1015 1.49 103196 16657 4 2233.104694 559.2827 General transcription factor II-I OS=Homo sapiens OX=9606 GN=GTF2I PE=1 SV=2 4.51 2818.2 - 2.09E+06 - - - 1.4249 - 3.897 0.446 - 420 1 2 1 0.0032 19 0 0 0 2.47E+08 1.66E+08 - - - 3.5672 1 221125_WJC_METTL3_EV_vs_WT_F07.16658.16658.4 2.15E-10 19/138 K.NLEEGHSSTVAAHYNELQEVGLEK[136.11].R sp|O43148|MCES_HUMAN 1 2661.2762 1.28 103197 16658 4 2661.275226 666.3263 mRNA cap guanine-N7 methyltransferase OS=Homo sapiens OX=9606 GN=RNMT PE=1 SV=1 4.62 2818.4 - 1.78E+06 - - - -0.3619 - 3.496 0.573 - 164.6 1 2 0 -0.001 24 0 0 0 1.90E+07 1.48E+07 - - - 4.6149 0.9999 221125_WJC_METTL3_EV_vs_WT_F07.16661.16661.4 1.73E-07 17/108 K.KAESPVKEEAVAEVVTITK.S "sp|P07197|NFM_HUMAN,tr|E7ESP9|E7ESP9_HUMAN" 2 2027.115 5.21 103200 16661 4 2027.115334 507.786 Neurofilament medium polypeptide OS=Homo sapiens OX=9606 GN=NEFM PE=1 SV=3 4.95 2818.8 - 729039 - - - 0.1465 - 3.347 0.497 - 260.6 1 2 1 0.0003 19 0 0 0 6.22E+06 1.19E+06 - - - 3.9605 1 221125_WJC_METTL3_EV_vs_WT_F07.16662.16662.3 5.45E-19 23/92 K.NLEEGHSSTVAAHYNELQEVGLEK.R sp|O43148|MCES_HUMAN 1 2653.262 2.71 103201 16662 3 2653.260118 885.4279 mRNA cap guanine-N7 methyltransferase OS=Homo sapiens OX=9606 GN=RNMT PE=1 SV=1 4.62 2818.9 - 511104 - - - -0.7052 - 4.808 0.691 - 557.4 1 2 0 -0.0019 24 0 0 0 5.88E+06 2.17E+06 - - - 9.8906 0.9998 221125_WJC_METTL3_EV_vs_WT_F07.16666.16666.4 3.18E-09 22/108 R.EDLQLDK[136.11]PASGVK[136.11]EEWYAR[166.11].L "sp|P78347|GTF2I_HUMAN,tr|A0A494C0Q7|A0A494C0Q7_HUMAN,tr|A0A494C1K3|A0A494C1K3_HUMAN" 3 2259.1382 1.49 103203 16666 4 2259.136014 565.7918 General transcription factor II-I OS=Homo sapiens OX=9606 GN=GTF2I PE=1 SV=2 4.51 2819.4 - 6.22E+06 - - - -0.9597 - 4.016 0.459 - 360.4 1 2 1 -0.0022 19 0 0 0 2.47E+08 1.66E+08 - - - 3.6908 1 221125_WJC_METTL3_EV_vs_WT_F07.16667.16667.3 3.18E-11 24/72 R.EDLQLDKPASGVKEEWYAR.L "sp|P78347|GTF2I_HUMAN,tr|A0A494C0Q7|A0A494C0Q7_HUMAN,tr|A0A494C1K3|A0A494C1K3_HUMAN" 3 2233.1015 1.69 103204 16667 3 2233.101116 745.3744 General transcription factor II-I OS=Homo sapiens OX=9606 GN=GTF2I PE=1 SV=2 4.51 2819.5 - 2.42E+06 - - - -0.1773 - 4.306 0.625 - 865.5 1 2 1 -0.0004 19 0 0 0 1.04E+08 6.14E+07 - - - 9.095 1 221125_WJC_METTL3_EV_vs_WT_F07.16668.16668.3 6.23E-07 24/72 R.EDLQLDK[136.11]PASGVK[136.11]EEWYAR[166.11].L "sp|P78347|GTF2I_HUMAN,tr|A0A494C0Q7|A0A494C0Q7_HUMAN,tr|A0A494C1K3|A0A494C1K3_HUMAN" 3 2259.1382 1.69 103205 16668 3 2259.136757 754.0533 General transcription factor II-I OS=Homo sapiens OX=9606 GN=GTF2I PE=1 SV=2 4.51 2819.6 - 2.28E+06 - - - -0.6308 - 3.972 0.584 - 732.6 1 2 1 -0.0014 19 0 0 0 1.04E+08 6.14E+07 - - - 8.4392 0.9999 221125_WJC_METTL3_EV_vs_WT_F07.16671.16671.4 0.000657 18/102 K.ADSGSSLQPLPHHPFNFR.S "sp|Q9HAZ2|PRD16_HUMAN,tr|D6RDW0|D6RDW0_HUMAN,tr|D6RFY3|D6RFY3_HUMAN,tr|H0YA13|H0YA13_HUMAN" 4 2005.9759 1.42 103208 16671 4 2005.972432 502.5012 Histone-lysine N-methyltransferase PRDM16 OS=Homo sapiens OX=9606 GN=PRDM16 PE=1 SV=3 6.96 2819.9 - 690538 - - - -1.7079 - 2.954 0.404 - 183.3 1 2 0 -0.0034 18 0 0 0 6.84E+06 4.81E+06 - - - 3.1125 0.9998 221125_WJC_METTL3_EV_vs_WT_F07.16673.16673.3 2.61E-08 17/64 R.FSREEFPTLQAAGDQDK.A sp|P48634|PRC2A_HUMAN 1 1937.9119 1.15 103210 16673 3 1937.908278 646.9779 Protein PRRC2A OS=Homo sapiens OX=9606 GN=PRRC2A PE=1 SV=3 4.32 2820.2 - 470832 - - - -1.8793 - 3.181 0.488 - 437.5 1 2 1 -0.0036 17 0 0 0 1.52E+07 1.32E+07 - - - 6.9031 1 221125_WJC_METTL3_EV_vs_WT_F07.16679.16679.3 8.14E-11 23/76 R.SSPTVYNSPTDKEDYMTDLR.T sp|Q96SK2|TM209_HUMAN 1 2318.0373 2.43 103214 16679 3 2318.035554 773.6864 Transmembrane protein 209 OS=Homo sapiens OX=9606 GN=TMEM209 PE=1 SV=2 4.23 2820.8 - 1.49E+06 - - - -0.7347 - 4.59 0.649 - 505.9 1 2 1 -0.0017 20 0 0 0 1.27E+07 5.23E+06 - - - 9.4722 0.8885 221125_WJC_METTL3_EV_vs_WT_F07.16680.16680.4 242 Mar-78 R.C[160.03]NGQDDC[160.03]GDEEDER.D sp|Q9NZR2|LRP1B_HUMAN 1 1697.553 17.87 103215 16680 4 1697.554158 425.3955 Low-density lipoprotein receptor-related protein 1B OS=Homo sapiens OX=9606 GN=LRP1B PE=1 SV=2 3.62 2821 - 968304 - - - 0.7075 - 0.444 0.163 - 2.6 1 2 0 0.0012 14 0 0 0 1.52E+07 8.50E+05 - - - 0.3489 0.9928 221125_WJC_METTL3_EV_vs_WT_F07.16681.16681.4 2.89E-06 15/84 W.GVDLASVEQHINSHR.G sp|P15924|DESP_HUMAN 1 1660.8281 16.14 103216 16681 4 1660.825634 416.2143 Desmoplakin OS=Homo sapiens OX=9606 GN=DSP PE=1 SV=3 5.99 2821.1 - 948504 - - - -1.5035 - 2.896 0.453 - 156.9 1 1 0 -0.0025 15 0 0 0 1.02E+07 6.34E+05 - - - 3.5487 0.9996 221125_WJC_METTL3_EV_vs_WT_F07.16682.16682.3 8.96E-08 18/64 R.FSR[166.11]EEFPTLQAAGDQDK[136.11].A sp|P48634|PRC2A_HUMAN 1 1955.9344 1.13 103217 16682 3 1955.927005 652.9854 Protein PRRC2A OS=Homo sapiens OX=9606 GN=PRRC2A PE=1 SV=3 4.32 2821.2 - 632981 - - - -3.7757 - 3.045 0.593 - 448.3 1 2 1 -0.0074 17 0 0 0 1.50E+07 1.32E+07 - - - 7.9624 1 221125_WJC_METTL3_EV_vs_WT_F07.16683.16683.3 3.38E-05 Oct-92 R.QDHPSSMGVYGQESGGFSGPGENR[166.11].S "sp|Q01844|EWS_HUMAN,tr|B0QYK0|B0QYK0_HUMAN" 2 2489.0541 2.91 103218 16683 3 2489.05346 830.692 RNA-binding protein EWS OS=Homo sapiens OX=9606 GN=EWSR1 PE=1 SV=1 4.65 2821.4 - 613041 - - - -0.2712 - 1.988 0.596 - 50.9 1 2 0 -0.0007 24 0 0 0 1.76E+07 6.06E+06 - - - 6.7805 0.9956 221125_WJC_METTL3_EV_vs_WT_F07.16684.16684.3 3.33E-06 15/64 L.R[166.11]C[160.03]IPALDSLTPANEDQK[136.11].L "sp|P10809|CH60_HUMAN,tr|A0A7I2V2X6|A0A7I2V2X6_HUMAN,tr|A0A7I2YQK6|A0A7I2YQK6_HUMAN,tr|A0A7I2V599|A0A7I2V599_HUMAN" 4 1944.9694 2.03 103219 16684 3 1944.968421 649.3304 "60 kDa heat shock protein, mitochondrial OS=Homo sapiens OX=9606 GN=HSPD1 PE=1 SV=2" 4.56 2821.5 - 455420 - - - -0.5013 - 2.921 0.434 - 289.4 1 1 0 -0.001 17 0 0 0 1.08E+07 5.31E+06 - - - 6.0864 1 221125_WJC_METTL3_EV_vs_WT_F07.16688.16688.3 1.05E-18 34/108 R.ATAPVPTVGEGYGYGHESELSQASAAAR.N "sp|Q9BWF3|RBM4_HUMAN,tr|E9PB51|E9PB51_HUMAN" 2 2775.31 1.56 103221 16688 3 2775.308819 926.1106 RNA-binding protein 4 OS=Homo sapiens OX=9606 GN=RBM4 PE=1 SV=1 4.75 2822 - 2.25E+06 - - - -0.4259 - 5.304 0.755 - 807.9 1 2 0 -0.0012 28 0 0 0 2.68E+09 1.72E+09 - - - 10.7957 1 221125_WJC_METTL3_EV_vs_WT_F07.16690.16690.3 2.45E-10 19/72 K.MQQENMK[136.11]PQEQLTLEPYER[166.11].D "sp|P22087|FBRL_HUMAN,tr|M0R299|M0R299_HUMAN,tr|M0QXL5|M0QXL5_HUMAN" 3 2409.1424 0.85 103223 16690 3 2409.146074 804.0547 rRNA 2'-O-methyltransferase fibrillarin OS=Homo sapiens OX=9606 GN=FBL PE=1 SV=2 4.49 2822.1 - 1.53E+06 - - - 1.5454 - 3.635 0.68 - 362 1 2 0 0.0037 19 0 0 0 2.84E+07 3.34E+07 - - - 9.2911 1 221125_WJC_METTL3_EV_vs_WT_F07.16691.16691.3 1.03E-09 20/80 K.QVYIPNYNKPNPNQISVNNVK.A "sp|Q13330|MTA1_HUMAN,tr|H0Y4T7|H0Y4T7_HUMAN,tr|E7ESY4|E7ESY4_HUMAN" 3 2442.2656 1.01 103224 16691 3 2442.264286 815.0958 Metastasis-associated protein MTA1 OS=Homo sapiens OX=9606 GN=MTA1 PE=1 SV=2 9.53 2822.3 - 1.29E+06 - - - -0.5208 - 3.234 0.553 - 417.1 1 2 0 -0.0013 21 0 0 0 1.79E+07 1.77E+07 - - - 7.519 0.9988 221125_WJC_METTL3_EV_vs_WT_F07.16693.16693.3 5.20E-10 21/76 S.KGSLGGGFSSGGFSGGSFSR.G "sp|P13645|K1C10_HUMAN,tr|A0A1B0GVI3|A0A1B0GVI3_HUMAN" 2 1834.8598 61.17 103226 16693 3 1834.859104 612.6272 "Keratin, type I cytoskeletal 10 OS=Homo sapiens OX=9606 GN=KRT10 PE=1 SV=6" 11 2822.5 - 734687 - - - -0.3929 - 4.473 0.53 - 476.2 1 1 0 -0.0007 20 0 0 0 4.02E+07 6.58E+05 - - - 8.0831 1 221125_WJC_METTL3_EV_vs_WT_F07.16696.16696.4 7.34E-06 12/108 R.GLLQDDAHPTLVTYADHSK[136.11].L "sp|Q86U44|MTA70_HUMAN,tr|F5H6D8|F5H6D8_HUMAN,tr|H0YFV6|H0YFV6_HUMAN,tr|B4DTN4|B4DTN4_HUMAN" 4 2088.0367 0.13 103228 16696 4 2088.034116 523.0165 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 5.13 2822.9 - 5.09E+06 - - - -1.2533 - 2.691 0.526 - 121.5 1 2 0 -0.0026 19 0 0 0 2.23E+07 1.76E+08 - - - 4.1384 1 221125_WJC_METTL3_EV_vs_WT_F07.16701.16701.3 2.84E-10 20/76 K.DVTEAEQAEEQARQEEQVVR.Q "sp|Q12788|TBL3_HUMAN,tr|J3KNP2|J3KNP2_HUMAN" 2 2343.0939 1.1 103232 16701 3 2343.094125 782.0386 Transducin beta-like protein 3 OS=Homo sapiens OX=9606 GN=TBL3 PE=1 SV=2 4.06 2823.4 - 1.74E+06 - - - 0.1127 - 3.574 0.633 - 445.9 1 2 1 0.0003 20 0 0 0 2.57E+07 2.34E+07 - - - 8.6872 1 221125_WJC_METTL3_EV_vs_WT_F07.16707.16707.3 3.04E-15 28/108 R.ATAPVPTVGEGYGYGHESELSQASAAAR[166.11].N "sp|Q9BWF3|RBM4_HUMAN,tr|E9PB51|E9PB51_HUMAN" 2 2785.3183 1.56 103236 16707 3 2785.316285 929.4467 RNA-binding protein 4 OS=Homo sapiens OX=9606 GN=RBM4 PE=1 SV=1 4.75 2824.1 - 1.38E+07 - - - -0.713 - 4.459 0.733 - 521.1 1 2 0 -0.002 28 0 0 0 2.68E+09 1.72E+09 - - - 10.151 0.9999 221125_WJC_METTL3_EV_vs_WT_F07.16708.16708.3 3.09E-07 18/76 K.DVTEAEQAEEQAR[166.11]QEEQVVR[166.11].Q "sp|Q12788|TBL3_HUMAN,tr|J3KNP2|J3KNP2_HUMAN" 2 2363.1104 1.1 103237 16708 3 2363.109106 788.7107 Transducin beta-like protein 3 OS=Homo sapiens OX=9606 GN=TBL3 PE=1 SV=2 4.06 2824.2 - 2.66E+06 - - - -0.548 - 3.183 0.545 - 346.7 1 2 1 -0.0013 20 0 0 0 2.57E+07 2.34E+07 - - - 7.4248 1 221125_WJC_METTL3_EV_vs_WT_F07.16709.16709.4 1.87E-10 24/162 R.ATAPVPTVGEGYGYGHESELSQASAAAR.N "sp|Q9BWF3|RBM4_HUMAN,tr|E9PB51|E9PB51_HUMAN" 2 2775.31 1.89 103238 16709 4 2775.313812 694.8348 RNA-binding protein 4 OS=Homo sapiens OX=9606 GN=RBM4 PE=1 SV=1 4.75 2824.2 - 3.46E+06 - - - 1.3732 - 3.961 0.609 - 240.5 1 2 0 0.0038 28 0 0 0 3.55E+08 1.88E+08 - - - 4.9531 1 221125_WJC_METTL3_EV_vs_WT_F07.16710.16710.3 1.11E-07 21/80 S.SKGSLGGGFSSGGFSGGSFSR.G "sp|P13645|K1C10_HUMAN,tr|A0A1B0GVI3|A0A1B0GVI3_HUMAN" 2 1921.8919 7.52 103239 16710 3 1921.898096 641.6379 "Keratin, type I cytoskeletal 10 OS=Homo sapiens OX=9606 GN=KRT10 PE=1 SV=6" 11 2824.3 - 1.81E+06 - - - 3.2478 - 4.025 0.612 - 415.9 1 1 1 0.0062 21 0 0 0 4.43E+07 5.88E+06 - - - 8.7 0.8383 221125_WJC_METTL3_EV_vs_WT_F07.16711.16711.4 5.82E-11 16/102 K.R[166.11]GLLQDDAHPTLVTYADH.S "sp|Q86U44|MTA70_HUMAN,tr|F5H6D8|F5H6D8_HUMAN,tr|H0YFV6|H0YFV6_HUMAN,tr|B4DTN4|B4DTN4_HUMAN" 4 2031.0049 0.08 103240 16711 4 2032.002672 508.7585 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 5.13 2824.4 - 1.11E+06 - - - 491.2588 - 3.343 0.584 - 222.1 1 1 0 0.9977 18 0 0 0 9.86E+05 1.22E+07 - - - 4.4462 0.9998 221125_WJC_METTL3_EV_vs_WT_F07.16712.16712.4 0.000475 15/120 R.FGPDTQHLVLNENC[160.03]ASVHNLR.S "sp|Q9BQ52|RNZ2_HUMAN,tr|G5E9D5|G5E9D5_HUMAN,tr|E7ES68|E7ES68_HUMAN,tr|H7C2I4|H7C2I4_HUMAN" 4 2420.1655 0.59 103241 16712 4 2420.164637 606.0487 Zinc phosphodiesterase ELAC protein 2 OS=Homo sapiens OX=9606 GN=ELAC2 PE=1 SV=2 5.99 2824.6 - 1.09E+06 - - - -0.3673 - 2.964 0.379 - 137.1 1 2 0 -0.0009 21 0 0 0 8.32E+06 1.40E+07 - - - 2.8838 1 221125_WJC_METTL3_EV_vs_WT_F07.16713.16713.3 8.12E-10 19/88 K.NALPPVLTTVNGQSPPEHSAPAK.V "sp|Q6PKG0|LARP1_HUMAN,tr|A0A0B4J210|A0A0B4J210_HUMAN,tr|H0YBM7|H0YBM7_HUMAN" 3 2324.2125 1.67 103242 16713 3 2324.215946 775.7448 La-related protein 1 OS=Homo sapiens OX=9606 GN=LARP1 PE=1 SV=2 6.75 2824.7 - 1.07E+06 - - - 1.4999 - 3.8 0.632 - 362.7 1 2 0 0.0035 23 0 0 0 3.55E+07 2.13E+07 - - - 8.717 0.9805 221125_WJC_METTL3_EV_vs_WT_F07.16714.16714.2 0.000161 Sep-36 K.QHGVNVSVNASATPFQQPS.G "sp|Q14157|UBP2L_HUMAN,tr|F8W726|F8W726_HUMAN,tr|H7C2T8|H7C2T8_HUMAN,tr|H0Y5H6|H0Y5H6_HUMAN" 4 1966.9497 - 103243 16714 2 1966.946192 984.4821 Ubiquitin-associated protein 2-like OS=Homo sapiens OX=9606 GN=UBAP2L PE=1 SV=2 6.74 2824.8 - 654987 - - - -1.785 - 1.886 0.494 - 98 1 1 0 -0.0035 19 0 0 0 - - - - - 4.2484 1 221125_WJC_METTL3_EV_vs_WT_F07.16718.16718.3 2.09E-08 20/76 K.DQVTAQEIFQDNHEDGPTAK[136.11].K sp|P13010|XRCC5_HUMAN 1 2250.028 1.77 103245 16718 3 2250.030522 751.0166 X-ray repair cross-complementing protein 5 OS=Homo sapiens OX=9606 GN=XRCC5 PE=1 SV=3 4.1 2825.3 - 943428 - - - 1.1124 - 3.932 0.597 - 335.2 1 2 0 0.0025 20 0 0 0 2.85E+07 1.61E+07 - - - 8.5169 0.9988 221125_WJC_METTL3_EV_vs_WT_F07.16719.16719.3 0.0396 Dec-44 K.NKLEGLEDALQK.A "sp|P48668|K2C6C_HUMAN,sp|P04259|K2C6B_HUMAN,sp|P02538|K2C6A_HUMAN" 3 1356.7249 793.17 103246 16719 3 1356.725537 453.2489 "Keratin, type II cytoskeletal 6C OS=Homo sapiens OX=9606 GN=KRT6C PE=1 SV=3" 4.68 2825.5 - 724171 - - - 0.4732 - 2.361 0.305 - 355.7 1 2 1 0.0006 12 0 0 0 8.18E+07 1.03E+05 - - - 4.3215 0.9997 221125_WJC_METTL3_EV_vs_WT_F07.16720.16720.4 8.45E-05 Dec-78 R.FKVEESYDLKDTLR.T sp|P29508|SPB3_HUMAN 1 1741.8887 12.14 103247 16720 4 1741.890095 436.4794 Serpin B3 OS=Homo sapiens OX=9606 GN=SERPINB3 PE=1 SV=2 4.78 2825.6 - 444543 - - - 0.8204 - 2.643 0.428 - 124.5 1 2 2 0.0014 14 0 0 0 5.94E+06 4.89E+05 - - - 3.3046 1 221125_WJC_METTL3_EV_vs_WT_F07.16728.16728.4 7.66E-06 26/162 R.ATAPVPTVGEGYGYGHESELSQASAAAR[166.11].N "sp|Q9BWF3|RBM4_HUMAN,tr|E9PB51|E9PB51_HUMAN" 2 2785.3183 1.89 103253 16728 4 2785.317398 697.3368 RNA-binding protein 4 OS=Homo sapiens OX=9606 GN=RBM4 PE=1 SV=1 4.75 2826.6 - 1.31E+07 - - - -0.3134 - 3.566 0.561 - 304.7 1 2 0 -0.0009 28 0 0 0 3.54E+08 1.88E+08 - - - 4.5035 0.9999 221125_WJC_METTL3_EV_vs_WT_F07.16730.16730.4 0.00271 24/120 K.MRPEIAGLKPANPPVLPAPQK.A "sp|Q9UKM7|MA1B1_HUMAN,tr|A0A804HK28|A0A804HK28_HUMAN,tr|H0YG20|H0YG20_HUMAN,tr|A0A804HKS1|A0A804HKS1_HUMAN,tr|H0YGV7|H0YGV7_HUMAN,tr|A0A804HL65|A0A804HL65_HUMAN,tr|A0A804HIP1|A0A804HIP1_HUMAN,tr|A0A804HK01|A0A804HK01_HUMAN,tr|A0A804HJ23|A0A804HJ23_HUMAN,tr|A0A804HHU1|A0A804HHU1_HUMAN,tr|A0A804HK86|A0A804HK86_HUMAN,tr|A0A804HL61|A0A804HL61_HUMAN,tr|A0A804HJ66|A0A804HJ66_HUMAN,tr|H0YI64|H0YI64_HUMAN,tr|A0A804HJW0|A0A804HJW0_HUMAN" 15 2223.2562 2.31 103255 16730 4 2223.254668 556.8213 "Endoplasmic reticulum mannosyl-oligosaccharide 1,2-alpha-mannosidase OS=Homo sapiens OX=9606 GN=MAN1B1 PE=1 SV=2" 9.99 2826.8 - 939161 - - - -0.6796 - 3 0.448 - 176.8 1 2 0 -0.0015 21 0 0 0 1.41E+07 6.11E+06 - - - 3.4882 0.997 221125_WJC_METTL3_EV_vs_WT_F07.16741.16741.2 0.00642 16/22 K.NKLEGLEDALQK.A "sp|P48668|K2C6C_HUMAN,sp|P04259|K2C6B_HUMAN,sp|P02538|K2C6A_HUMAN" 3 1356.7249 999 103264 16741 2 1356.722424 679.3697 "Keratin, type II cytoskeletal 6C OS=Homo sapiens OX=9606 GN=KRT6C PE=1 SV=3" 4.68 2828.2 - 1.24E+06 - - - -1.8213 - 2.945 0.366 - 911 1 2 1 -0.0025 12 0 0 0 3.50E+07 0.00E+00 - - - 4.5855 1 221125_WJC_METTL3_EV_vs_WT_F07.16743.16743.2 2.32E-12 18/54 R.ATAPVPTVGEGYGYGHESELSQASAAAR[166.11].N "sp|Q9BWF3|RBM4_HUMAN,tr|E9PB51|E9PB51_HUMAN" 2 2785.3183 5.11 103266 16743 2 2785.30638 1393.6664 RNA-binding protein 4 OS=Homo sapiens OX=9606 GN=RBM4 PE=1 SV=1 4.75 2828.5 - 541943 - - - -4.2692 - 3.264 0.727 - 355.1 1 2 0 -0.0119 28 0 0 0 1.27E+07 2.49E+06 - - - 7.3152 1 221125_WJC_METTL3_EV_vs_WT_F07.16749.16749.3 9.87E-09 21/72 R.GSENGNEGSLLER[166.11]EESTLK[136.11].K sp|Q5JSZ5|PRC2B_HUMAN 1 2065.9883 1.54 103270 16749 3 2065.983902 689.67 Protein PRRC2B OS=Homo sapiens OX=9606 GN=PRRC2B PE=1 SV=2 4.33 2829.1 - 2.31E+06 - - - -2.1171 - 3.71 0.675 - 626.9 1 2 1 -0.0044 19 0 0 0 5.22E+07 3.39E+07 - - - 9.2853 1 221125_WJC_METTL3_EV_vs_WT_F07.16752.16752.2 1.87E-14 25/54 R.ATAPVPTVGEGYGYGHESELSQASAAAR.N "sp|Q9BWF3|RBM4_HUMAN,tr|E9PB51|E9PB51_HUMAN" 2 2775.31 5.11 103273 16752 2 2775.310998 1388.6623 RNA-binding protein 4 OS=Homo sapiens OX=9606 GN=RBM4 PE=1 SV=1 4.75 2829.4 - 751020 - - - 0.3592 - 4.329 0.79 - 783.8 1 2 0 0.001 28 0 0 0 1.27E+07 2.49E+06 - - - 8.4782 1 221125_WJC_METTL3_EV_vs_WT_F07.16755.16755.4 1.72E-07 17/96 R.VKPAPDETSFSEALLKR.N "sp|Q12905|ILF2_HUMAN,tr|B4DY09|B4DY09_HUMAN,tr|X6R6Z1|X6R6Z1_HUMAN,tr|A0A0A0MRL0|A0A0A0MRL0_HUMAN" 4 1887.0102 1.15 103274 16755 4 1887.009072 472.7598 Interleukin enhancer-binding factor 2 OS=Homo sapiens OX=9606 GN=ILF2 PE=1 SV=2 6.15 2829.8 - 1.23E+06 - - - -0.5861 - 3.332 0.562 - 275.1 1 2 0 -0.0011 17 0 0 0 4.36E+07 3.80E+07 - - - 4.5352 1 221125_WJC_METTL3_EV_vs_WT_F07.16756.16756.4 7.78E-07 21/96 R.VK[136.11]PAPDETSFSEALLK[136.11]R[166.11].N "sp|Q12905|ILF2_HUMAN,tr|B4DY09|B4DY09_HUMAN,tr|X6R6Z1|X6R6Z1_HUMAN,tr|A0A0A0MRL0|A0A0A0MRL0_HUMAN" 4 1913.0468 1.15 103275 16756 4 1913.04402 479.269 Interleukin enhancer-binding factor 2 OS=Homo sapiens OX=9606 GN=ILF2 PE=1 SV=2 6.15 2830 - 1.09E+06 - - - -1.4783 - 3.418 0.542 - 233.4 1 2 0 -0.0028 17 0 0 0 4.36E+07 3.80E+07 - - - 4.3695 0.9882 221125_WJC_METTL3_EV_vs_WT_F07.16761.16761.4 8.38E-06 17/108 K.R[166.11]GLLQDDAHPTLVTYADHS.K "sp|Q86U44|MTA70_HUMAN,tr|F5H6D8|F5H6D8_HUMAN,tr|H0YFV6|H0YFV6_HUMAN,tr|B4DTN4|B4DTN4_HUMAN" 4 2118.037 0.57 103280 16761 4 2118.032346 530.5165 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 5.13 2830.6 - 774278 - - - -2.1742 - 3.435 0.445 - 294.5 1 1 0 -0.0046 19 0 0 0 7.26E+06 1.28E+07 - - - 3.5154 0.9999 221125_WJC_METTL3_EV_vs_WT_F07.16766.16766.3 2.50E-09 14/64 R.VK[136.11]PAPDETSFSEALLK[136.11]R[166.11].N "sp|Q12905|ILF2_HUMAN,tr|B4DY09|B4DY09_HUMAN,tr|X6R6Z1|X6R6Z1_HUMAN,tr|A0A0A0MRL0|A0A0A0MRL0_HUMAN" 4 1913.0468 2.34 103283 16766 3 1913.039378 638.6896 Interleukin enhancer-binding factor 2 OS=Homo sapiens OX=9606 GN=ILF2 PE=1 SV=2 6.15 2831.2 - 554638 - - - -3.9048 - 3.273 0.524 - 130.7 1 2 0 -0.0075 17 0 0 0 4.08E+07 1.74E+07 - - - 7.3755 1 221125_WJC_METTL3_EV_vs_WT_F07.16768.16768.3 7.62E-08 20/72 K.GGLNTPLHESDFSGVTPQR[166.11].Q sp|Q99459|CDC5L_HUMAN 1 2020.9842 1.85 103285 16768 3 2020.989216 674.6687 Cell division cycle 5-like protein OS=Homo sapiens OX=9606 GN=CDC5L PE=1 SV=2 5.32 2831.5 - 718049 - - - 2.4879 - 3.463 0.587 - 372.5 1 2 0 0.005 19 0 0 0 3.07E+07 1.66E+07 - - - 8.1348 0.9995 221125_WJC_METTL3_EV_vs_WT_F07.16773.16773.3 0.00143 22/72 K.GGLNTPLHESDFSGVTPQR.Q sp|Q99459|CDC5L_HUMAN 1 2010.9759 1.89 103288 16773 3 2010.98621 671.3326 Cell division cycle 5-like protein OS=Homo sapiens OX=9606 GN=CDC5L PE=1 SV=2 5.32 2832.1 - 1.20E+06 - - - 5.1179 - 3.505 0.452 - 669.2 1 2 0 0.0103 19 0 0 0 3.21E+07 1.69E+07 - - - 6.6578 1 221125_WJC_METTL3_EV_vs_WT_F07.16781.16781.3 4.13E-05 23/96 K.LGHPEALSAGTGSPQPPSFTYAQQR.E "sp|Q15942|ZYX_HUMAN,tr|H7C3D3|H7C3D3_HUMAN,tr|H0Y2Y8|H0Y2Y8_HUMAN" 3 2596.267 6.52 103294 16781 3 2596.268905 866.4296 Zyxin OS=Homo sapiens OX=9606 GN=ZYX PE=1 SV=1 6.75 2833 - 1.19E+06 - - - 0.7284 - 4.161 0.561 - 305.2 1 2 0 0.0019 25 0 0 0 3.32E+07 5.10E+06 - - - 8.0742 0.9938 221125_WJC_METTL3_EV_vs_WT_F07.16782.16782.3 5.74E-06 15/100 T.APTSGGPK[136.11]PSTASAVPELATDPELEK[136.11].K "sp|Q86U44|MTA70_HUMAN,tr|B4E349|B4E349_HUMAN,tr|F5H6D8|F5H6D8_HUMAN,tr|H0YFV6|H0YFV6_HUMAN,tr|B4DTN4|B4DTN4_HUMAN" 5 2565.3145 0.001 103295 16782 3 2565.313209 856.1121 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 4.41 2833.1 - 671068 - - - -0.4947 - 3.005 0.417 - 117.3 1 1 0 -0.0013 26 0 0 0 0.00E+00 1.77E+07 - - - 5.7201 0.9994 221125_WJC_METTL3_EV_vs_WT_F07.16786.16786.4 7.83E-05 Nov-96 K.LK[136.11]DPEK[136.11]GPVPTFQPFQR[166.11].S "sp|P18615|NELFE_HUMAN,tr|A2ABK4|A2ABK4_HUMAN,tr|A0A0A0MSN9|A0A0A0MSN9_HUMAN,tr|E9PD43|E9PD43_HUMAN,tr|A0A0A0MT02|A0A0A0MT02_HUMAN,tr|A0A0G2JI50|A0A0G2JI50_HUMAN" 6 2009.0945 0.4 103299 16786 4 2009.093561 503.2809 Negative elongation factor E OS=Homo sapiens OX=9606 GN=NELFE PE=1 SV=3 8.59 2833.7 - 456581 - - - -0.4509 - 2.115 0.395 - 62.5 1 2 2 -0.0009 17 0 0 0 5.01E+06 1.25E+07 - - - 2.9239 0.998 221125_WJC_METTL3_EV_vs_WT_F07.16789.16789.3 0.00295 15/60 R.K[136.11]EAESC[160.03]DC[160.03]LQGFQLTH.S "sp|P04350|TBB4A_HUMAN,sp|A6NNZ2|TBB8B_HUMAN,sp|P07437|TBB5_HUMAN,sp|P68371|TBB4B_HUMAN,sp|Q3ZCM7|TBB8_HUMAN,tr|Q5ST81|Q5ST81_HUMAN,tr|Q5JP53|Q5JP53_HUMAN,tr|M0R042|M0R042_HUMAN,tr|A0A075B736|A0A075B736_HUMAN,tr|M0R1I1|M0R1I1_HUMAN,tr|Q5SQY0|Q5SQY0_HUMAN" 11 1929.844 0.52 103300 16789 3 1929.84229 644.2886 Tubulin beta-4A chain OS=Homo sapiens OX=9606 GN=TUBB4A PE=1 SV=2 4.65 2834.1 - 696377 - - - -0.911 - 3.032 0.512 - 413.5 1 1 0 -0.0018 16 0 0 0 3.51E+06 6.77E+06 - - - 7.0939 1 221125_WJC_METTL3_EV_vs_WT_F07.16791.16791.3 2.75E-06 21/88 K.IPMTPTSSFVSPPPPTASPHSNR.T sp|Q7Z5L9|I2BP2_HUMAN 1 2404.1845 1.7 103302 16791 3 2404.190378 802.4021 Interferon regulatory factor 2-binding protein 2 OS=Homo sapiens OX=9606 GN=IRF2BP2 PE=1 SV=2 9.76 2834.3 - 745079 - - - 2.4324 - 3.155 0.589 - 390.7 1 2 0 0.0058 23 0 0 0 1.61E+07 9.45E+06 - - - 7.8006 0.9985 221125_WJC_METTL3_EV_vs_WT_F07.16794.16794.3 6.75E-06 14/60 R.KEAESC[160.03]DC[160.03]LQGFQLTH.S "sp|P04350|TBB4A_HUMAN,sp|A6NNZ2|TBB8B_HUMAN,sp|P07437|TBB5_HUMAN,sp|P68371|TBB4B_HUMAN,sp|Q3ZCM7|TBB8_HUMAN,tr|Q5ST81|Q5ST81_HUMAN,tr|Q5JP53|Q5JP53_HUMAN,tr|M0R042|M0R042_HUMAN,tr|A0A075B736|A0A075B736_HUMAN,tr|M0R1I1|M0R1I1_HUMAN,tr|Q5SQY0|Q5SQY0_HUMAN" 11 1921.8298 0.52 103305 16794 3 1921.827293 641.6172 Tubulin beta-4A chain OS=Homo sapiens OX=9606 GN=TUBB4A PE=1 SV=2 4.65 2834.7 - 528945 - - - -1.3295 - 2.484 0.625 - 255.8 1 1 0 -0.0026 16 0 0 0 3.51E+06 6.77E+06 - - - 7.842 0.9999 221125_WJC_METTL3_EV_vs_WT_F07.16796.16796.3 0.000145 Nov-40 R.RAPFDLFENKK.K "sp|P08238|HS90B_HUMAN,sp|Q58FF7|H90B3_HUMAN" 2 1363.7248 0.95 103307 16796 3 1363.724603 455.5822 Heat shock protein HSP 90-beta OS=Homo sapiens OX=9606 GN=HSP90AB1 PE=1 SV=4 8.59 2835 - 214859 - - - -0.1701 - 2.325 0.35 - 136.6 1 2 0 -0.0002 11 0 0 0 1.25E+07 1.32E+07 - - - 4.839 1 221125_WJC_METTL3_EV_vs_WT_F07.16801.16801.3 4.86E-08 19/72 R.GLLQDDAHPTLVTYADHSK[136.11].L "sp|Q86U44|MTA70_HUMAN,tr|F5H6D8|F5H6D8_HUMAN,tr|H0YFV6|H0YFV6_HUMAN,tr|B4DTN4|B4DTN4_HUMAN" 4 2088.0367 0.001 103310 16801 3 2088.039858 697.0195 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 5.13 2835.6 - 8.45E+06 - - - 1.4966 - 3.497 0.592 - 386.6 1 2 0 0.0031 19 0 0 0 0.00E+00 2.01E+08 - - - 8.215 1 221125_WJC_METTL3_EV_vs_WT_F07.16803.16803.3 6.02E-06 23/72 K.GSR[166.11]PPLILQSQSLPC[160.03]SSPR[166.11].D "sp|Q6KC79|NIPBL_HUMAN,tr|A0A590UJS4|A0A590UJS4_HUMAN" 2 2099.106 1.12 103312 16803 3 2099.111348 700.7093 Nipped-B-like protein OS=Homo sapiens OX=9606 GN=NIPBL PE=1 SV=2 10.35 2835.8 - 1.05E+06 - - - 2.5249 - 4.479 0.622 - 553.7 1 2 0 0.0053 19 0 0 0 2.24E+07 1.99E+07 - - - 9.1569 1 221125_WJC_METTL3_EV_vs_WT_F07.16805.16805.2 3.71E-13 18/32 R.SGGGFSSGSAGIINYQR.R sp|P04264|K2C1_HUMAN 1 1656.7856 1.94 103314 16805 2 1656.786928 829.4001 "Keratin, type II cytoskeletal 1 OS=Homo sapiens OX=9606 GN=KRT1 PE=1 SV=6" 8.46 2836.1 - 409916 - - - 0.8028 - 3.505 0.701 - 1292.2 1 2 0 0.0013 17 0 0 0 1.45E+07 7.49E+06 - - - 7.3017 1 221125_WJC_METTL3_EV_vs_WT_F07.16810.16810.3 8.10E-11 21/72 K.GSRPPLILQSQSLPC[160.03]SSPR.D "sp|Q6KC79|NIPBL_HUMAN,tr|A0A590UJS4|A0A590UJS4_HUMAN" 2 2079.0895 1.14 103317 16810 3 2079.094351 694.0371 Nipped-B-like protein OS=Homo sapiens OX=9606 GN=NIPBL PE=1 SV=2 10.35 2836.6 - 1.68E+06 - - - 2.3294 - 3.462 0.531 - 431.7 1 2 0 0.0048 19 0 0 0 2.24E+07 1.95E+07 - - - 7.5098 0.9596 221125_WJC_METTL3_EV_vs_WT_F07.16811.16811.3 0.000456 14/64 L.LQDDAHPTLVTYADHSK[136.11].L "sp|Q86U44|MTA70_HUMAN,tr|F5H6D8|F5H6D8_HUMAN,tr|H0YFV6|H0YFV6_HUMAN,tr|B4DTN4|B4DTN4_HUMAN" 4 1917.9312 0.05 103318 16811 3 1917.92292 640.3177 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 5.13 2836.8 - 465351 - - - -4.3203 - 2.651 0.461 - 254.7 1 1 0 -0.0083 17 0 0 0 7.37E+05 1.38E+07 - - - 6.1404 0.9994 221125_WJC_METTL3_EV_vs_WT_F07.16812.16812.3 0.0128 14/44 R.TVITEEFKVPDK.M sp|Q96I24|FUBP3_HUMAN 1 1404.75 1.64 103319 16812 3 1404.751566 469.2573 Far upstream element-binding protein 3 OS=Homo sapiens OX=9606 GN=FUBP3 PE=1 SV=2 4.68 2836.9 - 903793 - - - 1.0813 - 2.768 0.331 - 197.9 1 2 1 0.0015 12 0 0 0 1.13E+07 6.88E+06 - - - 5.052 0.9996 221125_WJC_METTL3_EV_vs_WT_F07.16814.16814.3 6.14E-07 12/100 R.LSVGAVSSKPTTPTIATPQTVSVPNK.V sp|Q9HBM6|TAF9B_HUMAN 1 2579.417 1.32 103321 16814 3 2579.426229 860.813 Transcription initiation factor TFIID subunit 9B OS=Homo sapiens OX=9606 GN=TAF9B PE=1 SV=1 10 2837.1 - 328510 - - - 3.5651 - 2.287 0.455 - 102.8 1 2 0 0.0092 26 0 0 0 1.67E+07 1.27E+07 - - - 5.5134 0.9918 221125_WJC_METTL3_EV_vs_WT_F07.16815.16815.4 0.00451 9/102 K.TAEALDKDGWLHTGDIGK.W "sp|P33121|ACSL1_HUMAN,tr|H0Y9U7|H0Y9U7_HUMAN,tr|B7Z3Z9|B7Z3Z9_HUMAN,tr|E7EPM6|E7EPM6_HUMAN" 4 1925.9483 0.98 103322 16815 4 1925.950176 482.4944 Long-chain-fatty-acid--CoA ligase 1 OS=Homo sapiens OX=9606 GN=ACSL1 PE=1 SV=1 4.66 2837.3 - 234522 - - - 0.971 - 1.809 0.267 - 47.6 1 2 1 0.0019 18 0 0 0 1.81E+06 1.84E+06 - - - 1.7525 0.9671 221125_WJC_METTL3_EV_vs_WT_F07.16816.16816.2 0.654 Apr-34 K.GSGFSDPLTGAPSQYLER.L sp|P0DMQ9|CH089_HUMAN 1 1880.8905 3.58 103323 16816 2 1880.889479 941.4525 Putative uncharacterized protein C8orf89 OS=Homo sapiens OX=9606 GN=C8orf89 PE=2 SV=1 4.37 2837.4 - 219466 - - - -0.52 - 0.997 0.111 - 29.8 1 2 0 -0.001 18 0 0 0 1.98E+06 5.54E+05 - - - -0.1468 1 221125_WJC_METTL3_EV_vs_WT_F07.16819.16819.3 0.00024 15/72 K.VQASLAANTFTITGHAETK[136.11].Q "sp|P20290|BTF3_HUMAN,tr|A0A7I2V3T6|A0A7I2V3T6_HUMAN,tr|D6RDG3|D6RDG3_HUMAN,tr|A0A7I2V5Y3|A0A7I2V5Y3_HUMAN,tr|H0Y9Y1|H0Y9Y1_HUMAN,tr|A0A7I2YQL2|A0A7I2YQL2_HUMAN" 6 1967.0204 1.07 103324 16819 3 1967.022784 656.6807 Transcription factor BTF3 OS=Homo sapiens OX=9606 GN=BTF3 PE=1 SV=1 6.72 2837.8 - 697328 - - - 1.2349 - 3.361 0.497 - 218.4 1 2 0 0.0024 19 0 0 0 8.52E+06 7.98E+06 - - - 7.0586 0.9998 221125_WJC_METTL3_EV_vs_WT_F07.16821.16821.3 0.000466 14/72 K.VQASLAANTFTITGHAETK.Q "sp|P20290|BTF3_HUMAN,tr|A0A7I2V3T6|A0A7I2V3T6_HUMAN,tr|D6RDG3|D6RDG3_HUMAN,tr|A0A7I2V5Y3|A0A7I2V5Y3_HUMAN,tr|H0Y9Y1|H0Y9Y1_HUMAN,tr|A0A7I2YQL2|A0A7I2YQL2_HUMAN" 6 1959.0062 1.08 103326 16821 3 1959.011584 654.0093 Transcription factor BTF3 OS=Homo sapiens OX=9606 GN=BTF3 PE=1 SV=1 6.72 2838.1 - 673420 - - - 2.7713 - 2.635 0.427 - 171.7 1 2 0 0.0054 19 0 0 0 8.52E+06 7.89E+06 - - - 5.6795 0.9999 221125_WJC_METTL3_EV_vs_WT_F07.16822.16822.3 1.11E-07 16/56 K.HLEINPDHPIVETLR[166.11].Q sp|P08238|HS90B_HUMAN 1 1791.9507 1 103327 16822 3 1791.95548 598.3242 Heat shock protein HSP 90-beta OS=Homo sapiens OX=9606 GN=HSP90AB1 PE=1 SV=4 5.27 2838.2 - 472845 - - - 2.6658 - 3.017 0.497 - 310.1 1 2 0 0.0048 15 0 0 0 9.30E+06 9.31E+06 - - - 6.9612 0.9994 221125_WJC_METTL3_EV_vs_WT_F07.16823.16823.4 2.75E-05 17/108 R.C[160.03]VFELPAENDK[136.11]PHDVEINK[136.11].L sp|O95292|VAPB_HUMAN 1 2269.102 1.14 103328 16823 4 2269.109627 568.2828 Vesicle-associated membrane protein-associated protein B\C OS=Homo sapiens OX=9606 GN=VAPB PE=1 SV=3 4.5 2838.3 - 454621 - - - 3.3687 - 3.023 0.384 - 138.5 1 2 0 0.0076 19 0 0 0 2.01E+07 1.77E+07 - - - 2.9404 0.9997 221125_WJC_METTL3_EV_vs_WT_F07.16824.16824.3 5.45E-07 18/52 K.K[136.11]K[136.11]ELEEIVQPIISK[136.11].L "sp|P11021|BIP_HUMAN,tr|A0A7P0TB36|A0A7P0TB36_HUMAN,tr|A0A7P0TAI0|A0A7P0TAI0_HUMAN" 3 1677.0139 0.54 103329 16824 3 1677.017193 560.0119 Endoplasmic reticulum chaperone BiP OS=Homo sapiens OX=9606 GN=HSPA5 PE=1 SV=2 6.23 2838.4 - 454075 - - - 1.9797 - 2.681 0.465 - 569.6 1 2 1 0.0033 14 0 0 0 4.88E+07 9.03E+07 - - - 6.3442 0.9987 221125_WJC_METTL3_EV_vs_WT_F07.16826.16826.3 9.42E-07 Oct-64 R.SGGGFSSGSAGIINYQR.R sp|P04264|K2C1_HUMAN 1 1656.7856 2.81 103331 16826 3 1656.7883 553.2691 "Keratin, type II cytoskeletal 1 OS=Homo sapiens OX=9606 GN=KRT1 PE=1 SV=6" 8.46 2838.7 - 428318 - - - 1.6309 - 2.066 0.275 - 120.8 1 2 0 0.0027 17 0 0 0 4.31E+06 1.54E+06 - - - 3.4384 1 221125_WJC_METTL3_EV_vs_WT_F07.16828.16828.3 3.03E-05 16/96 K.LGHPEALSAGTGSPQPPSFTYAQQR[166.11].E "sp|Q15942|ZYX_HUMAN,tr|H7C3D3|H7C3D3_HUMAN,tr|H0Y2Y8|H0Y2Y8_HUMAN" 3 2606.2753 5.22 103333 16828 3 2606.279543 869.7657 Zyxin OS=Homo sapiens OX=9606 GN=ZYX PE=1 SV=1 6.75 2838.9 - 327701 - - - 1.6341 - 3.257 0.592 - 154 1 2 0 0.0043 25 0 0 0 2.47E+07 4.73E+06 - - - 7.8556 0.9999 221125_WJC_METTL3_EV_vs_WT_F07.16831.16831.2 2.51E-07 Oct-36 R.EANNGSSPAGSLADAMSQK[136.11].H "sp|P51692|STA5B_HUMAN,tr|C9J4I3|C9J4I3_HUMAN" 2 1841.8305 0.001 103336 16831 2 1841.830001 921.9225 Signal transducer and activator of transcription 5B OS=Homo sapiens OX=9606 GN=STAT5B PE=1 SV=2 4.37 2839.3 - 134335 - - - -0.2736 - 1.902 0.626 - 217.5 1 2 0 -0.0005 19 0 0 0 0.00E+00 1.44E+06 - - - 5.2451 0.9999 221125_WJC_METTL3_EV_vs_WT_F07.16834.16834.3 1.45E-06 17/52 K.SGKWEGLVYAPPGK.E "sp|Q9Y2W1|TR150_HUMAN,tr|A0A3B3ITZ9|A0A3B3ITZ9_HUMAN" 2 1487.7773 2.02 103337 16834 3 1487.778621 496.933 Thyroid hormone receptor-associated protein 3 OS=Homo sapiens OX=9606 GN=THRAP3 PE=1 SV=2 8.22 2839.7 - 3.14E+06 - - - 0.9114 - 2.971 0.508 - 309.8 1 2 1 0.0014 14 0 0 0 5.59E+07 2.77E+07 - - - 7.0971 1 221125_WJC_METTL3_EV_vs_WT_F07.16835.16835.3 1.08E-06 19/56 R.EHHTDEYEYDELIVR.R sp|P22735|TGM1_HUMAN 1 1946.8646 137.91 103338 16835 3 1946.867665 649.9622 Protein-glutamine gamma-glutamyltransferase K OS=Homo sapiens OX=9606 GN=TGM1 PE=1 SV=4 4.35 2839.8 - 1.61E+06 - - - 1.5558 - 3.281 0.623 - 449.1 1 2 0 0.003 15 0 0 0 1.38E+07 1.00E+05 - - - 8.5853 0.9997 221125_WJC_METTL3_EV_vs_WT_F07.16841.16841.4 2.85E-06 21/108 R.C[160.03]VFELPAENDKPHDVEINK.L sp|O95292|VAPB_HUMAN 1 2253.0736 1.13 103344 16841 4 2253.084278 564.2757 Vesicle-associated membrane protein-associated protein B\C OS=Homo sapiens OX=9606 GN=VAPB PE=1 SV=3 4.5 2840.6 - 472532 - - - 4.7468 - 3.442 0.533 - 248.4 1 2 0 0.0107 19 0 0 0 2.01E+07 1.79E+07 - - - 4.2804 1 221125_WJC_METTL3_EV_vs_WT_F07.16842.16842.4 2.93E-08 23/108 K.DRPENVHGGILADDMGLGK.T "sp|Q14527|HLTF_HUMAN,tr|A0A0C4DGA6|A0A0C4DGA6_HUMAN" 2 1992.9687 1.52 103345 16842 4 1992.971964 499.2495 Helicase-like transcription factor OS=Homo sapiens OX=9606 GN=HLTF PE=1 SV=2 4.66 2840.7 - 402114 - - - 1.6257 - 4.146 0.547 - 339.5 1 2 0 0.0032 19 0 0 0 1.72E+07 1.13E+07 - - - 4.4673 0.925 221125_WJC_METTL3_EV_vs_WT_F07.16843.16843.3 0.0054 Aug-72 K.R[166.11]GLLQDDAHPTLVTYADHS.K "sp|Q86U44|MTA70_HUMAN,tr|F5H6D8|F5H6D8_HUMAN,tr|H0YFV6|H0YFV6_HUMAN,tr|B4DTN4|B4DTN4_HUMAN" 4 2118.037 0.09 103346 16843 3 2118.03728 707.0196 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 5.13 2840.8 - 344180 - - - 0.1553 - 2.084 0.283 - 71.9 1 1 0 0.0003 19 0 0 0 7.99E+05 9.12E+06 - - - 3.4991 0.9998 221125_WJC_METTL3_EV_vs_WT_F07.16849.16849.3 5.08E-07 15/52 K.SGK[136.11]WEGLVYAPPGK[136.11].E "sp|Q9Y2W1|TR150_HUMAN,tr|A0A3B3ITZ9|A0A3B3ITZ9_HUMAN" 2 1503.8057 1.93 103351 16849 3 1503.809178 502.2758 Thyroid hormone receptor-associated protein 3 OS=Homo sapiens OX=9606 GN=THRAP3 PE=1 SV=2 8.22 2841.6 - 1.71E+06 - - - 2.3361 - 2.718 0.532 - 234.3 1 2 1 0.0035 14 0 0 0 5.59E+07 2.90E+07 - - - 7.1276 0.9999 221125_WJC_METTL3_EV_vs_WT_F07.16850.16850.3 1.88E-07 18/52 K.KKELEEIVQPIISK.L "sp|P11021|BIP_HUMAN,tr|A0A7P0TB36|A0A7P0TB36_HUMAN,tr|A0A7P0TAI0|A0A7P0TAI0_HUMAN" 3 1652.9713 0.54 103352 16850 3 1652.973163 551.9977 Endoplasmic reticulum chaperone BiP OS=Homo sapiens OX=9606 GN=HSPA5 PE=1 SV=2 6.23 2841.7 - 714688 - - - 1.1434 - 2.982 0.516 - 570.6 1 2 1 0.0019 14 0 0 0 4.88E+07 9.01E+07 - - - 7.196 1 221125_WJC_METTL3_EV_vs_WT_F07.16852.16852.4 1.51E-09 16/90 R.R[166.11]EPFFHGQDNYDQLVR[166.11].L "sp|P19784|CSK22_HUMAN,tr|H3BNI9|H3BNI9_HUMAN,tr|H3BSA1|H3BSA1_HUMAN" 3 2039.9717 1 103354 16852 4 2039.969915 511.0002 Casein kinase II subunit alpha' OS=Homo sapiens OX=9606 GN=CSNK2A2 PE=1 SV=1 5.38 2841.9 - 471317 - - - -0.8569 - 3.561 0.562 - 320.3 1 2 0 -0.0017 16 0 0 0 2.97E+06 2.98E+06 - - - 4.5645 0.9999 221125_WJC_METTL3_EV_vs_WT_F07.16853.16853.4 6.36E-05 16/84 K.HLEINPDHPIVETLR.Q sp|P08238|HS90B_HUMAN 1 1781.9424 1.25 103355 16853 4 1781.943694 446.4929 Heat shock protein HSP 90-beta OS=Homo sapiens OX=9606 GN=HSP90AB1 PE=1 SV=4 5.27 2842.1 - 396137 - - - 0.7077 - 2.673 0.45 - 233.4 1 2 0 0.0013 15 0 0 0 4.66E+06 3.74E+06 - - - 3.4943 0.9999 221125_WJC_METTL3_EV_vs_WT_F07.16854.16854.4 3.79E-07 15/90 R.REPFFHGQDNYDQLVR.L "sp|P19784|CSK22_HUMAN,tr|H3BNI9|H3BNI9_HUMAN,tr|H3BSA1|H3BSA1_HUMAN" 3 2019.9551 1 103356 16854 4 2019.956654 505.9961 Casein kinase II subunit alpha' OS=Homo sapiens OX=9606 GN=CSNK2A2 PE=1 SV=1 5.38 2842.2 - 383381 - - - 0.7579 - 3.183 0.454 - 291.2 1 2 0 0.0015 16 0 0 0 2.97E+06 2.98E+06 - - - 3.585 0.9731 221125_WJC_METTL3_EV_vs_WT_F07.16855.16855.3 7.54E-06 13/60 L.QDDAHPTLVTYADHSK[136.11].L "sp|Q86U44|MTA70_HUMAN,tr|F5H6D8|F5H6D8_HUMAN,tr|H0YFV6|H0YFV6_HUMAN,tr|B4DTN4|B4DTN4_HUMAN" 4 1804.8471 0.18 103357 16855 3 1804.852088 602.623 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 5.13 2842.3 - 379387 - - - 2.7404 - 2.315 0.421 - 208.9 1 1 0 0.0049 16 0 0 0 1.28E+06 7.13E+06 - - - 5.3862 1 221125_WJC_METTL3_EV_vs_WT_F07.16856.16856.3 2.73E-07 22/72 R.QHPQPYIFPDSPGGTSYER[166.11].Y "sp|Q9Y6M9|NDUB9_HUMAN,tr|A0A7I2V620|A0A7I2V620_HUMAN,tr|A0A3B3IT57|A0A3B3IT57_HUMAN,tr|E7EWZ0|E7EWZ0_HUMAN,tr|E9PF49|E9PF49_HUMAN,tr|E9PH64|E9PH64_HUMAN" 6 2185.0104 1.27 103358 16856 3 2184.998291 729.3441 NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 9 OS=Homo sapiens OX=9606 GN=NDUFB9 PE=1 SV=3 5.32 2842.4 - 378228 - - - -5.5428 - 3.724 0.609 - 589.9 1 2 0 -0.0121 19 0 0 0 6.02E+06 4.73E+06 - - - 8.5566 1 221125_WJC_METTL3_EV_vs_WT_F07.16862.16862.3 2.72E-10 26/72 K.DRPENVHGGILADDMGLGK.T "sp|Q14527|HLTF_HUMAN,tr|A0A0C4DGA6|A0A0C4DGA6_HUMAN" 2 1992.9687 0.56 103362 16862 3 1992.970308 665.3302 Helicase-like transcription factor OS=Homo sapiens OX=9606 GN=HLTF PE=1 SV=2 4.66 2843.1 - 1.33E+06 - - - 0.7948 - 4.698 0.614 - 1030.9 1 2 0 0.0016 19 0 0 0 1.66E+07 2.95E+07 - - - 9.1861 1 221125_WJC_METTL3_EV_vs_WT_F07.16864.16864.3 2.19E-09 27/100 R.AGEARPGPTAESASGPSEDPSVNFLK.N "sp|Q13501|SQSTM_HUMAN,tr|E9PFW8|E9PFW8_HUMAN,tr|E7EMC7|E7EMC7_HUMAN" 3 2570.2249 3.73 103364 16864 3 2570.229862 857.7489 Sequestosome-1 OS=Homo sapiens OX=9606 GN=SQSTM1 PE=1 SV=1 4.41 2843.4 - 1.10E+06 - - - 1.9403 - 5.13 0.58 - 630 1 2 0 0.005 26 0 0 0 1.04E+07 2.78E+06 - - - 8.7668 1 221125_WJC_METTL3_EV_vs_WT_F07.16865.16865.3 2.31E-12 16/80 K.NSESGTATTGTSLSAPDITVR.N "sp|Q7Z353|HDX_HUMAN,tr|E2QRN0|E2QRN0_HUMAN" 2 2063.9971 3.47 103365 16865 3 2064.001337 689.0063 Highly divergent homeobox OS=Homo sapiens OX=9606 GN=HDX PE=1 SV=1 4.37 2843.5 - 775309 - - - 2.0494 - 3.153 0.639 - 265.4 1 2 0 0.0042 21 0 0 0 1.32E+07 3.79E+06 - - - 8.4162 1 221125_WJC_METTL3_EV_vs_WT_F07.16866.16866.3 8.68E-12 22/92 R.EAPATQASSTTQLTDTQVLAAENK.S "sp|Q9UNF1|MAGD2_HUMAN,tr|Q5H909|Q5H909_HUMAN" 2 2474.2136 1.44 103366 16866 3 2474.213785 825.7452 Melanoma-associated antigen D2 OS=Homo sapiens OX=9606 GN=MAGED2 PE=1 SV=2 4.14 2843.6 - 693016 - - - 0.0582 - 3.988 0.648 - 562.6 1 2 0 0.0001 24 0 0 0 1.68E+07 1.16E+07 - - - 8.9773 0.9996 221125_WJC_METTL3_EV_vs_WT_F07.16869.16869.3 0.0426 13/64 K.QGTQYTFSSIER[166.11]EEYGK[136.11].L sp|Q08945|SSRP1_HUMAN 1 2039.9555 0.89 103369 16869 3 2039.959018 680.9924 FACT complex subunit SSRP1 OS=Homo sapiens OX=9606 GN=SSRP1 PE=1 SV=1 4.79 2844 - 540790 - - - 1.7147 - 3.08 0.397 - 271 1 2 1 0.0035 17 0 0 0 4.54E+06 5.11E+06 - - - 5.8071 0.9999 221125_WJC_METTL3_EV_vs_WT_F07.16872.16872.3 7.78E-05 Oct-52 R.K[136.11]LC[160.03]LNIC[160.03]VGESGDR[166.11].L "sp|P62913|RL11_HUMAN,tr|Q5VVC8|Q5VVC8_HUMAN" 2 1637.7984 1.62 103372 16872 3 1637.798944 546.9401 60S ribosomal protein L11 OS=Homo sapiens OX=9606 GN=RPL11 PE=1 SV=2 6.06 2844.4 - 399835 - - - 0.3132 - 2.167 0.398 - 130.8 1 2 0 0.0005 14 0 0 0 3.63E+06 2.24E+06 - - - 5.0324 1 221125_WJC_METTL3_EV_vs_WT_F07.16874.16874.2 1.15E-17 20/40 K.NSESGTATTGTSLSAPDITVR.N "sp|Q7Z353|HDX_HUMAN,tr|E2QRN0|E2QRN0_HUMAN" 2 2063.9971 14.53 103374 16874 2 2064.003066 1033.0058 Highly divergent homeobox OS=Homo sapiens OX=9606 GN=HDX PE=1 SV=1 4.37 2844.7 - 336648 - - - 2.8871 - 4.284 0.723 - 1124.5 1 2 0 0.006 21 0 0 0 8.71E+06 5.99E+05 - - - 7.9561 1 221125_WJC_METTL3_EV_vs_WT_F07.16876.16876.3 2.22E-09 20/76 K.GSLESPATDVFGSTEEGEK[136.11]R[166.11].W sp|O00232|PSD12_HUMAN 1 2112.993 0.87 103376 16876 3 2112.996683 705.3383 26S proteasome non-ATPase regulatory subunit 12 OS=Homo sapiens OX=9606 GN=PSMD12 PE=1 SV=3 4.25 2844.9 - 318732 - - - 1.7298 - 3.779 0.5 - 482.7 1 2 0 0.0037 20 0 0 0 2.88E+07 3.31E+07 - - - 7.3388 0.9999 221125_WJC_METTL3_EV_vs_WT_F07.16877.16877.3 2.29E-05 13/40 R.R[166.11]APFDLFENK[136.11]K[136.11].K "sp|P08238|HS90B_HUMAN,sp|Q58FF7|H90B3_HUMAN" 2 1389.7615 0.94 103377 16877 3 1389.762652 464.2611 Heat shock protein HSP 90-beta OS=Homo sapiens OX=9606 GN=HSP90AB1 PE=1 SV=4 8.59 2845.1 - 308345 - - - 0.8253 - 2.044 0.42 - 205.3 1 2 0 0.0011 11 0 0 0 9.28E+06 9.90E+06 - - - 5.2532 1 221125_WJC_METTL3_EV_vs_WT_F07.16881.16881.3 6.69E-12 19/72 K.EVTINPDTTC[160.03]GNDWVC[160.03]EHR.W "sp|P0DTE8|AMY1C_HUMAN,sp|P0DTE7|AMY1B_HUMAN,sp|P04746|AMYP_HUMAN,sp|P0DUB6|AMY1A_HUMAN,sp|P19961|AMY2B_HUMAN" 5 2301.9743 11.71 103379 16881 3 2301.977511 768.332 Alpha-amylase 1C OS=Homo sapiens OX=9606 GN=AMY1C PE=1 SV=1 4.31 2845.6 - 1.98E+06 - - - 1.4036 - 3.727 0.7 - 447.4 1 2 0 0.0032 19 0 0 0 3.00E+07 2.56E+06 - - - 9.5756 1 221125_WJC_METTL3_EV_vs_WT_F07.16882.16882.4 2.53E-10 23/108 K.DR[166.11]PENVHGGILADDMGLGK[136.11].T "sp|Q14527|HLTF_HUMAN,tr|A0A0C4DGA6|A0A0C4DGA6_HUMAN" 2 2010.9912 1.7 103380 16882 4 2010.994539 503.7551 Helicase-like transcription factor OS=Homo sapiens OX=9606 GN=HLTF PE=1 SV=2 4.66 2845.7 - 1.64E+06 - - - 1.6634 - 4.064 0.581 - 389.7 1 2 0 0.0033 19 0 0 0 1.96E+07 1.15E+07 - - - 4.7564 1 221125_WJC_METTL3_EV_vs_WT_F07.16886.16886.3 2.44E-08 22/72 R.QHPQPYIFPDSPGGTSYER.Y "sp|Q9Y6M9|NDUB9_HUMAN,tr|A0A7I2V620|A0A7I2V620_HUMAN,tr|A0A3B3IT57|A0A3B3IT57_HUMAN,tr|E7EWZ0|E7EWZ0_HUMAN,tr|E9PF49|E9PF49_HUMAN,tr|E9PH64|E9PH64_HUMAN" 6 2175.0021 0.91 103384 16886 3 2175.005424 726.008 NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 9 OS=Homo sapiens OX=9606 GN=NDUFB9 PE=1 SV=3 5.32 2846.1 - 877055 - - - 1.5136 - 3.851 0.628 - 601.6 1 2 0 0.0033 19 0 0 0 7.44E+06 8.16E+06 - - - 8.8533 1 221125_WJC_METTL3_EV_vs_WT_F07.16887.16887.3 4.36E-12 17/104 R.LAPASNMTSQRPVSSTGINFDNPSVQK.A sp|Q9HCD5|NCOA5_HUMAN 1 2845.4029 2.38 103385 16887 3 2845.407073 949.4749 Nuclear receptor coactivator 5 OS=Homo sapiens OX=9606 GN=NCOA5 PE=1 SV=2 8.75 2846.2 - 785266 - - - 1.482 - 3.349 0.627 - 284.1 1 2 0 0.0042 27 0 0 0 7.94E+06 3.33E+06 - - - 8.31 1 221125_WJC_METTL3_EV_vs_WT_F07.16889.16889.3 2.95E-12 16/64 R.SQSSHSYDDSTLPLIDR[166.11].N "sp|O60716|CTND1_HUMAN,tr|A0A669KB62|A0A669KB62_HUMAN,tr|A0A804HK15|A0A804HK15_HUMAN,tr|A0A669KB05|A0A669KB05_HUMAN,tr|C9JZR2|C9JZR2_HUMAN,tr|H0YC95|H0YC95_HUMAN,tr|A0A804HIL4|A0A804HIL4_HUMAN" 7 1929.8944 0.8 103387 16889 3 1929.901123 644.3054 Catenin delta-1 OS=Homo sapiens OX=9606 GN=CTNND1 PE=1 SV=1 4.41 2846.5 - 563626 - - - 3.4992 - 3.06 0.667 - 222.1 1 2 0 0.0068 17 0 0 0 1.28E+07 1.61E+07 - - - 8.8 0.9999 221125_WJC_METTL3_EV_vs_WT_F07.16890.16890.4 3.49E-07 18/78 K.K[136.11]K[136.11]ELEEIVQPIISK[136.11].L "sp|P11021|BIP_HUMAN,tr|A0A7P0TB36|A0A7P0TB36_HUMAN,tr|A0A7P0TAI0|A0A7P0TAI0_HUMAN" 3 1677.0139 0.62 103388 16890 4 1677.015085 420.2607 Endoplasmic reticulum chaperone BiP OS=Homo sapiens OX=9606 GN=HSPA5 PE=1 SV=2 6.23 2846.6 - 548267 - - - 0.7227 - 3.014 0.581 - 402.7 1 2 1 0.0012 14 0 0 0 6.40E+06 1.03E+07 - - - 4.6842 0.9999 221125_WJC_METTL3_EV_vs_WT_F07.16891.16891.4 0.000546 20/126 K.VLQPANLGSTLTPHHPPALPSK[136.11].L sp|Q96T58|MINT_HUMAN 1 2282.2627 1.58 103389 16891 4 2282.269044 571.5729 Msx2-interacting protein OS=Homo sapiens OX=9606 GN=SPEN PE=1 SV=1 8.74 2846.7 - 467697 - - - 2.8012 - 2.743 0.476 - 218.8 1 2 0 0.0064 22 0 0 0 2.01E+07 1.27E+07 - - - 3.6975 0.9992 221125_WJC_METTL3_EV_vs_WT_F07.16892.16892.4 0.00266 Nov-84 K.HLEINPDHPIVETLR[166.11].Q sp|P08238|HS90B_HUMAN 1 1791.9507 1.25 103390 16892 4 1791.951457 448.995 Heat shock protein HSP 90-beta OS=Homo sapiens OX=9606 GN=HSP90AB1 PE=1 SV=4 5.27 2846.8 - 337797 - - - 0.4208 - 1.78 0.312 - 111 1 2 0 0.0008 15 0 0 0 4.66E+06 3.74E+06 - - - 2.1478 0.9997 221125_WJC_METTL3_EV_vs_WT_F07.16893.16893.4 0.000256 16/78 K.KKELEEIVQPIISK.L "sp|P11021|BIP_HUMAN,tr|A0A7P0TB36|A0A7P0TB36_HUMAN,tr|A0A7P0TAI0|A0A7P0TAI0_HUMAN" 3 1652.9713 0.61 103391 16893 4 1652.973374 414.2501 Endoplasmic reticulum chaperone BiP OS=Homo sapiens OX=9606 GN=HSPA5 PE=1 SV=2 6.23 2847 - 306394 - - - 1.271 - 2.656 0.427 - 347.7 1 2 1 0.0021 14 0 0 0 6.21E+06 1.02E+07 - - - 3.2975 0.9943 221125_WJC_METTL3_EV_vs_WT_F07.16894.16894.4 0.0807 Aug-84 R.EHHTDEYEYDELIVR.R sp|P22735|TGM1_HUMAN 1 1946.8646 32.4 103392 16894 4 1946.867549 487.7234 Protein-glutamine gamma-glutamyltransferase K OS=Homo sapiens OX=9606 GN=TGM1 PE=1 SV=4 4.35 2847.1 - 229276 - - - 1.4963 - 1.308 0.242 - 38.6 1 2 0 0.0029 15 0 0 0 8.76E+06 2.70E+05 - - - 1.4276 1 221125_WJC_METTL3_EV_vs_WT_F07.16898.16898.4 7.14E-11 21/114 R.VHLDIQVGEHANNYPEIAAK.D sp|Q7Z7H5|TMED4_HUMAN 1 2217.1178 2.32 103395 16898 4 2217.120651 555.2867 Transmembrane emp24 domain-containing protein 4 OS=Homo sapiens OX=9606 GN=TMED4 PE=1 SV=1 5.27 2847.5 - 2.03E+06 - - - 1.2719 - 3.383 0.605 - 331.2 1 2 0 0.0028 20 0 0 0 2.61E+07 1.13E+07 - - - 4.8986 0.9999 221125_WJC_METTL3_EV_vs_WT_F07.16899.16899.4 2.67E-05 11/126 K.VLQPANLGSTLTPHHPPALPSK.L sp|Q96T58|MINT_HUMAN 1 2274.2485 1.57 103396 16899 4 2274.251848 569.5694 Msx2-interacting protein OS=Homo sapiens OX=9606 GN=SPEN PE=1 SV=1 8.74 2847.6 - 1.04E+06 - - - 1.4937 - 2.421 0.418 - 63.8 1 2 0 0.0034 22 0 0 0 2.03E+07 1.29E+07 - - - 3.1526 1 221125_WJC_METTL3_EV_vs_WT_F07.16901.16901.3 1.18E-11 17/104 R.LAPASNMTSQR[166.11]PVSSTGINFDNPSVQK[136.11].A sp|Q9HCD5|NCOA5_HUMAN 1 2863.4253 2.38 103398 16901 3 2863.424824 955.4824 Nuclear receptor coactivator 5 OS=Homo sapiens OX=9606 GN=NCOA5 PE=1 SV=2 8.75 2847.8 - 408437 - - - -0.1753 - 3.333 0.657 - 297.9 1 2 0 -0.0005 27 0 0 0 7.94E+06 3.33E+06 - - - 8.6344 0.9833 221125_WJC_METTL3_EV_vs_WT_F07.16902.16902.3 0.0147 Oct-52 R.NKDLEGQLSDLEQR.L "sp|Q86YM7|HOME1_HUMAN,tr|Q86YM6|Q86YM6_HUMAN" 2 1643.8115 0.9 103399 16902 3 1643.816598 548.9444 Homer protein homolog 1 OS=Homo sapiens OX=9606 GN=HOMER1 PE=1 SV=2 4.32 2847.9 - 358977 - - - 3.1147 - 1.966 0.275 - 128.8 1 2 1 0.0051 14 0 0 0 4.33E+06 4.82E+06 - - - 3.4011 1 221125_WJC_METTL3_EV_vs_WT_F07.16903.16903.3 3.79E-14 15/76 R.VEVKPYVLDDQMC[160.03]DEC[160.03]QGTR.C sp|Q8NE35|CPEB3_HUMAN 1 2441.0661 1.63 103400 16903 3 2441.067068 814.696 Cytoplasmic polyadenylation element-binding protein 3 OS=Homo sapiens OX=9606 GN=CPEB3 PE=1 SV=2 4.11 2848 - 338782 - - - 0.3834 - 3.183 0.737 - 247.8 1 2 0 0.0009 20 0 0 0 2.49E+06 1.53E+06 - - - 9.5655 0.9768 221125_WJC_METTL3_EV_vs_WT_F07.16905.16905.2 0.00701 Aug-36 R.GLLQDDAHPTLVTYADHSK[136.11].L "sp|Q86U44|MTA70_HUMAN,tr|F5H6D8|F5H6D8_HUMAN,tr|H0YFV6|H0YFV6_HUMAN,tr|B4DTN4|B4DTN4_HUMAN" 4 2088.0367 0.001 103402 16905 2 2089.037699 1045.0256 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 5.13 2848.3 - 141021 - - - 479.3814 - 1.681 0.423 - 112 1 2 0 1.001 19 0 0 0 0.00E+00 1.95E+06 - - - 3.1279 0.9932 221125_WJC_METTL3_EV_vs_WT_F07.16908.16908.4 0.071 Sep-96 R.GISTK[136.11]PVYIPEVELNHK[136.11].L "sp|Q14258|TRI25_HUMAN,tr|A0A3B3IUA7|A0A3B3IUA7_HUMAN" 2 1939.075 1.34 103403 16908 4 1939.074124 485.776 E3 ubiquitin\ISG15 ligase TRIM25 OS=Homo sapiens OX=9606 GN=TRIM25 PE=1 SV=2 6.76 2848.7 - 189724 - - - -0.4327 - 1.782 0.216 - 42.9 1 2 0 -0.0008 17 0 0 0 7.83E+06 5.83E+06 - - - 1.3064 0.9779 221125_WJC_METTL3_EV_vs_WT_F07.16909.16909.3 0.0602 Aug-44 R.LIDLHSPSEIVK[136.11].Q "sp|P60866|RS20_HUMAN,tr|A0A7P0S5H5|A0A7P0S5H5_HUMAN,tr|G3XAN0|G3XAN0_HUMAN" 3 1357.7697 1.73 103404 16909 3 1357.771154 453.5972 40S ribosomal protein S20 OS=Homo sapiens OX=9606 GN=RPS20 PE=1 SV=1 5.32 2848.8 - 303073 - - - 1.0952 - 1.794 0.113 - 70.1 1 2 0 0.0015 12 0 0 0 1.39E+07 8.04E+06 - - - 1.4194 1 221125_WJC_METTL3_EV_vs_WT_F07.16911.16911.3 1.82E-13 19/76 R.VHLDIQVGEHANNYPEIAAK.D sp|Q7Z7H5|TMED4_HUMAN 1 2217.1178 1.99 103406 16911 3 2217.114486 740.0466 Transmembrane emp24 domain-containing protein 4 OS=Homo sapiens OX=9606 GN=TMED4 PE=1 SV=1 5.27 2849 - 758274 - - - -1.5087 - 4.14 0.671 - 320.8 1 2 0 -0.0033 20 0 0 0 1.04E+07 5.22E+06 - - - 9.4667 1 221125_WJC_METTL3_EV_vs_WT_F07.16918.16918.3 1.14E-06 15/92 R.EAPATQASSTTQLTDTQVLAAENK[136.11].S "sp|Q9UNF1|MAGD2_HUMAN,tr|Q5H909|Q5H909_HUMAN" 2 2482.2278 1.44 103411 16918 3 2482.228087 828.4166 Melanoma-associated antigen D2 OS=Homo sapiens OX=9606 GN=MAGED2 PE=1 SV=2 4.14 2849.9 - 1.10E+06 - - - 0.0991 - 2.866 0.558 - 205.9 1 2 0 0.0002 24 0 0 0 1.68E+07 1.16E+07 - - - 7.2066 0.9666 221125_WJC_METTL3_EV_vs_WT_F07.16919.16919.3 0.302 Jul-44 R.LIDLHSPSEIVK.Q "sp|P60866|RS20_HUMAN,tr|A0A7P0S5H5|A0A7P0S5H5_HUMAN,tr|G3XAN0|G3XAN0_HUMAN" 3 1349.7555 1.74 103412 16919 3 1349.757294 450.9258 40S ribosomal protein S20 OS=Homo sapiens OX=9606 GN=RPS20 PE=1 SV=1 5.32 2850.1 - 482270 - - - 1.3536 - 1.403 0.159 - 64.7 1 2 0 0.0018 12 0 0 0 1.39E+07 8.00E+06 - - - 1.2508 0.9938 221125_WJC_METTL3_EV_vs_WT_F07.16920.16920.4 0.255 13/78 K.QEALKNDLVEALKR.K tr|B1AK88|B1AK88_HUMAN 1 1625.9101 0.87 103413 16920 4 1625.912131 407.4848 F-actin-capping protein subunit beta OS=Homo sapiens OX=9606 GN=CAPZB PE=1 SV=1 6.18 2850.2 - 389380 - - - 1.2676 - 2.347 0.269 - 178.8 1 2 1 0.0021 14 0 0 0 7.05E+06 8.10E+06 - - - 1.8773 1 221125_WJC_METTL3_EV_vs_WT_F07.16926.16926.3 1.78E-07 26/80 K.YQGDGIVEDEEETMENNEEKK.D "sp|Q9NYF8|BCLF1_HUMAN,tr|H0YF63|H0YF63_HUMAN,tr|E9PK91|E9PK91_HUMAN,tr|H0YF14|H0YF14_HUMAN" 4 2485.0439 2.59 103417 16926 3 2485.045306 829.3552 Bcl-2-associated transcription factor 1 OS=Homo sapiens OX=9606 GN=BCLAF1 PE=1 SV=2 3.89 2851 - 1.68E+06 - - - 0.5823 - 4.405 0.665 - 687.8 1 2 0 0.0014 21 0 0 0 1.45E+08 5.59E+07 - - - 9.5085 1 221125_WJC_METTL3_EV_vs_WT_F07.16927.16927.4 7.37E-07 22/126 K.TVGFGTNNSEHITYLEHNPYEK.F sp|Q99459|CDC5L_HUMAN 1 2549.1823 1.27 103418 16927 4 2549.186086 638.3028 Cell division cycle 5-like protein OS=Homo sapiens OX=9606 GN=CDC5L PE=1 SV=2 5.31 2851.1 - 1.04E+06 - - - 1.4922 - 4.098 0.589 - 262 1 2 0 0.0038 22 0 0 0 1.13E+08 8.92E+07 - - - 4.8131 1 221125_WJC_METTL3_EV_vs_WT_F07.16928.16928.3 0.00177 25/80 K.YQGDGIVEDEEETMENNEEK[136.11]K[136.11].D "sp|Q9NYF8|BCLF1_HUMAN,tr|H0YF63|H0YF63_HUMAN,tr|E9PK91|E9PK91_HUMAN,tr|H0YF14|H0YF14_HUMAN" 4 2501.0723 2.59 103419 16928 3 2501.071643 834.698 Bcl-2-associated transcription factor 1 OS=Homo sapiens OX=9606 GN=BCLAF1 PE=1 SV=2 3.89 2851.3 - 927012 - - - -0.2463 - 4.615 0.666 - 644.3 1 2 0 -0.0006 21 0 0 0 1.45E+08 5.59E+07 - - - 9.6315 0.9979 221125_WJC_METTL3_EV_vs_WT_F07.16931.16931.3 1.19E-06 14/88 A.VHVQGQEPLTASMLASAPPQEQK[136.11].Q "sp|P11940|PABP1_HUMAN,tr|H0YAS6|H0YAS6_HUMAN,tr|H0YB75|H0YB75_HUMAN,tr|H0YAS7|H0YAS7_HUMAN,tr|A0A7I2YQE4|A0A7I2YQE4_HUMAN,tr|A0A7I2V649|A0A7I2V649_HUMAN,tr|H0YAR2|H0YAR2_HUMAN,tr|E7ERJ7|E7ERJ7_HUMAN,tr|A0A7I2YQ88|A0A7I2YQ88_HUMAN,tr|A0A087WTT1|A0A087WTT1_HUMAN,tr|A0A7I2YQ90|A0A7I2YQ90_HUMAN,tr|A0A7I2V4N4|A0A7I2V4N4_HUMAN,tr|E7EQV3|E7EQV3_HUMAN" 13 2453.2464 1.94 103422 16931 3 2453.246509 818.7561 Polyadenylate-binding protein 1 OS=Homo sapiens OX=9606 GN=PABPC1 PE=1 SV=2 5.4 2851.7 - 429019 - - - 0.0408 - 2.89 0.539 - 109.8 1 1 0 0.0001 23 0 0 0 2.22E+07 1.14E+07 - - - 7.0389 0.9854 221125_WJC_METTL3_EV_vs_WT_F07.16935.16935.3 0.0314 Aug-84 K.VSGDSSHTETTAEEVPEDPLLK.A "sp|Q6W2J9|BCOR_HUMAN,tr|H7BZ37|H7BZ37_HUMAN,tr|H7C2V9|H7C2V9_HUMAN,tr|H7BYY2|H7BYY2_HUMAN,tr|H7C231|H7C231_HUMAN" 5 2340.0969 1.92 103426 16935 3 2340.109479 781.0396 BCL-6 corepressor OS=Homo sapiens OX=9606 GN=BCOR PE=1 SV=1 4.08 2852.2 - 190403 - - - 5.384 - 1.959 0.31 - 38.8 1 2 0 0.0126 22 0 0 0 2.40E+06 1.25E+06 - - - 3.5869 1 221125_WJC_METTL3_EV_vs_WT_F07.16938.16938.4 9.43E-08 31/144 K.LGHPEALSAGTGSPQPPSFTYAQQR.E "sp|Q15942|ZYX_HUMAN,tr|H7C3D3|H7C3D3_HUMAN,tr|H0Y2Y8|H0Y2Y8_HUMAN" 3 2596.267 3.93 103427 16938 4 2596.269935 650.074 Zyxin OS=Homo sapiens OX=9606 GN=ZYX PE=1 SV=1 6.75 2852.6 - 1.26E+06 - - - 1.1251 - 4.622 0.485 - 510.2 1 2 0 0.0029 25 0 0 0 1.03E+07 2.62E+06 - - - 3.9336 1 221125_WJC_METTL3_EV_vs_WT_F07.16940.16940.3 6.81E-09 19/76 K.GSLESPATDVFGSTEEGEKR.W sp|O00232|PSD12_HUMAN 1 2094.9706 0.87 103429 16940 3 2094.969457 699.3308 26S proteasome non-ATPase regulatory subunit 12 OS=Homo sapiens OX=9606 GN=PSMD12 PE=1 SV=3 4.25 2852.7 - 2.07E+06 - - - -0.5255 - 3.723 0.563 - 395.2 1 2 0 -0.0011 20 0 0 0 2.88E+07 3.31E+07 - - - 8.0057 0.9999 221125_WJC_METTL3_EV_vs_WT_F07.16941.16941.3 7.31E-06 16/52 R.ER[166.11]DFTSLENTVEER[166.11].L sp|Q07065|CKAP4_HUMAN 1 1743.8178 1.26 103430 16941 3 1743.820389 582.2799 Cytoskeleton-associated protein 4 OS=Homo sapiens OX=9606 GN=CKAP4 PE=1 SV=2 4.25 2852.9 - 788505 - - - 1.4577 - 3.354 0.514 - 570.6 1 2 1 0.0025 14 0 0 0 1.05E+07 8.34E+06 - - - 7.4859 1 221125_WJC_METTL3_EV_vs_WT_F07.16942.16942.3 1.58E-12 25/88 A.VHVQGQEPLTASMLASAPPQEQK.Q "sp|P11940|PABP1_HUMAN,tr|H0YAS6|H0YAS6_HUMAN,tr|H0YB75|H0YB75_HUMAN,tr|H0YAS7|H0YAS7_HUMAN,tr|A0A7I2YQE4|A0A7I2YQE4_HUMAN,tr|A0A7I2V649|A0A7I2V649_HUMAN,tr|H0YAR2|H0YAR2_HUMAN,tr|E7ERJ7|E7ERJ7_HUMAN,tr|A0A7I2YQ88|A0A7I2YQ88_HUMAN,tr|A0A087WTT1|A0A087WTT1_HUMAN,tr|A0A7I2YQ90|A0A7I2YQ90_HUMAN,tr|A0A7I2V4N4|A0A7I2V4N4_HUMAN,tr|E7EQV3|E7EQV3_HUMAN" 13 2445.2322 1.47 103431 16942 3 2445.236995 816.0847 Polyadenylate-binding protein 1 OS=Homo sapiens OX=9606 GN=PABPC1 PE=1 SV=2 5.4 2853 - 619804 - - - 1.9573 - 4.451 0.648 - 443.5 1 1 0 0.0048 23 0 0 0 1.32E+07 8.94E+06 - - - 9.266 0.9961 221125_WJC_METTL3_EV_vs_WT_F07.16947.16947.3 0.0393 Aug-32 K.LVKEEVFWR.N sp|Q96A49|SYAP1_HUMAN 1 1204.6604 1.14 103436 16947 3 1204.661888 402.5608 Synapse-associated protein 1 OS=Homo sapiens OX=9606 GN=SYAP1 PE=1 SV=1 6.14 2853.6 - 158613 - - - 1.1987 - 1.796 0.293 - 104.8 1 2 1 0.0014 9 0 0 0 2.69E+06 2.37E+06 - - - 3.571 1 221125_WJC_METTL3_EV_vs_WT_F07.16950.16950.3 2.41E-06 24/96 K.C[160.03]SLQAAAILDANDAHQTETSSSQVK[136.11].D sp|Q9UHB9|SRP68_HUMAN 1 2652.2541 1.17 103437 16950 3 2652.252999 885.092 Signal recognition particle subunit SRP68 OS=Homo sapiens OX=9606 GN=SRP68 PE=1 SV=2 4.54 2854.1 - 1.15E+06 - - - -0.4049 - 4.805 0.667 - 701.4 1 2 0 -0.0011 25 0 0 0 1.16E+07 9.86E+06 - - - 9.5873 1 221125_WJC_METTL3_EV_vs_WT_F07.16953.16953.3 1.79E-15 30/96 K.C[160.03]SLQAAAILDANDAHQTETSSSQVK.D sp|Q9UHB9|SRP68_HUMAN 1 2644.2399 1.17 103440 16953 3 2644.244103 882.4206 Signal recognition particle subunit SRP68 OS=Homo sapiens OX=9606 GN=SRP68 PE=1 SV=2 4.54 2854.4 - 1.13E+06 - - - 1.5997 - 6.161 0.728 - 1223.6 1 2 0 0.0042 25 0 0 0 1.16E+07 9.86E+06 - - - 10.8384 1 221125_WJC_METTL3_EV_vs_WT_F07.16955.16955.4 0.000199 18/108 R.FSGWYDADLSPAGHEEAKR.G sp|P18669|PGAM1_HUMAN 1 2134.9708 1.04 103442 16955 4 2134.974178 534.75 Phosphoglycerate mutase 1 OS=Homo sapiens OX=9606 GN=PGAM1 PE=1 SV=2 4.75 2854.5 - 910944 - - - 1.5672 - 3.19 0.499 - 196.5 1 2 0 0.0033 19 0 0 0 1.05E+07 1.01E+07 - - - 3.9608 0.9998 221125_WJC_METTL3_EV_vs_WT_F07.16956.16956.3 0.472 15/52 K.QEALKNDLVEALKR.K tr|B1AK88|B1AK88_HUMAN 1 1625.9101 1.14 103443 16956 3 1625.909889 542.9773 F-actin-capping protein subunit beta OS=Homo sapiens OX=9606 GN=CAPZB PE=1 SV=1 6.18 2854.7 - 680567 - - - -0.1113 - 2.707 0.419 - 314 1 2 1 -0.0002 14 0 0 0 7.33E+06 6.44E+06 - - - 5.8579 0.9996 221125_WJC_METTL3_EV_vs_WT_F07.16961.16961.3 6.17E-06 18/40 K.FAAQELIEVK[136.11]R[166.11].G "sp|Q86U44|MTA70_HUMAN,tr|F5H6D8|F5H6D8_HUMAN,tr|H0YFV6|H0YFV6_HUMAN,tr|B4DTN4|B4DTN4_HUMAN" 4 1320.7521 0.001 103448 16961 3 1320.754777 441.258 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 6.14 2855.3 - 262504 - - - 2.0602 - 2.657 0.291 - 329.3 1 2 0 0.0027 11 0 0 0 0.00E+00 7.78E+07 - - - 4.5597 1 221125_WJC_METTL3_EV_vs_WT_F07.16964.16964.4 1.71E-09 22/126 K.TVGFGTNNSEHITYLEHNPYEK[136.11].F sp|Q99459|CDC5L_HUMAN 1 2557.1965 1.27 103449 16964 4 2557.19652 640.3064 Cell division cycle 5-like protein OS=Homo sapiens OX=9606 GN=CDC5L PE=1 SV=2 5.31 2855.7 - 5.57E+06 - - - 0.0149 - 3.788 0.548 - 260.1 1 2 0 0 22 0 0 0 1.13E+08 8.96E+07 - - - 4.4316 1 221125_WJC_METTL3_EV_vs_WT_F07.16965.16965.3 2.61E-09 16/68 R.SGQGFHGNSEVNAILSPR[166.11].S "sp|Q8TB72|PUM2_HUMAN,tr|C9JW01|C9JW01_HUMAN" 2 1878.9212 1.37 103450 16965 3 1878.920744 627.3143 Pumilio homolog 2 OS=Homo sapiens OX=9606 GN=PUM2 PE=1 SV=2 6.47 2855.8 - 2.01E+06 - - - -0.239 - 2.829 0.601 - 295.9 1 2 0 -0.0004 18 0 0 0 1.69E+08 1.23E+08 - - - 7.8299 1 221125_WJC_METTL3_EV_vs_WT_F07.16966.16966.3 3.41E-11 24/76 K.EAEDVIWEDSASENQEGLRK.L sp|O75792|RNH2A_HUMAN 1 2304.0506 1.39 103451 16966 3 2304.054065 769.0241 Ribonuclease H2 subunit A OS=Homo sapiens OX=9606 GN=RNASEH2A PE=1 SV=2 4 2855.9 - 1.31E+06 - - - 1.5043 - 3.779 0.604 - 753.6 1 2 0 0.0035 20 0 0 0 7.85E+06 5.66E+06 - - - 8.4983 1 221125_WJC_METTL3_EV_vs_WT_F07.16967.16967.3 0.000241 15/72 K.QITSYGETC[160.03]PGLEQYAIK[136.11]K[136.11].F sp|P50990|TCPQ_HUMAN 1 2201.1009 0.51 103452 16967 3 2201.101631 734.7076 T-complex protein 1 subunit theta OS=Homo sapiens OX=9606 GN=CCT8 PE=1 SV=4 6.13 2856.1 - 1.29E+06 - - - 0.323 - 2.791 0.488 - 192.7 1 2 0 0.0007 19 0 0 0 5.43E+06 1.08E+07 - - - 6.5022 0.9998 221125_WJC_METTL3_EV_vs_WT_F07.16968.16968.4 5.92E-05 23/96 R.LKEDQQTVLKPQFYEIK.A sp|Q9BSC4|NOL10_HUMAN 1 2106.1361 1.04 103453 16968 4 2106.139118 527.5413 Nucleolar protein 10 OS=Homo sapiens OX=9606 GN=NOL10 PE=1 SV=1 6.18 2856.1 - 1.09E+06 - - - 1.4296 - 3.796 0.453 - 497.7 1 2 1 0.003 17 0 0 0 1.48E+07 1.42E+07 - - - 3.6312 1 221125_WJC_METTL3_EV_vs_WT_F07.16969.16969.4 1.00E-06 17/108 R.FSGWYDADLSPAGHEEAK[136.11]R[166.11].G sp|P18669|PGAM1_HUMAN 1 2152.9933 1.03 103454 16969 4 2152.992239 539.2556 Phosphoglycerate mutase 1 OS=Homo sapiens OX=9606 GN=PGAM1 PE=1 SV=2 4.75 2856.3 - 583240 - - - -0.4937 - 2.978 0.492 - 248.2 1 2 0 -0.0011 19 0 0 0 1.04E+07 1.01E+07 - - - 3.8772 0.9998 221125_WJC_METTL3_EV_vs_WT_F07.16973.16973.4 1.86E-05 14/90 R.AELHPVELK[136.11]PFQDYQK[136.11].L sp|P48634|PRC2A_HUMAN 1 1957.028 2.3 103458 16973 4 1957.026186 490.2643 Protein PRRC2A OS=Homo sapiens OX=9606 GN=PRRC2A PE=1 SV=3 5.45 2856.8 - 415586 - - - -0.9336 - 2.605 0.388 - 114 1 2 0 -0.0018 16 0 0 0 3.66E+07 1.59E+07 - - - 2.9399 1 221125_WJC_METTL3_EV_vs_WT_F07.16976.16976.3 2.41E-12 25/72 K.QTIDNSQGAYQEAFDISK[136.11]K[136.11].E sp|P27348|1433T_HUMAN 1 2158.0513 1.1 103459 16976 3 2158.052164 720.3577 14-3-3 protein theta OS=Homo sapiens OX=9606 GN=YWHAQ PE=1 SV=1 4.56 2857.2 - 2.15E+06 - - - 0.3878 - 3.74 0.665 - 813 1 2 0 0.0008 19 0 0 0 8.48E+07 7.74E+07 - - - 9.1946 1 221125_WJC_METTL3_EV_vs_WT_F07.16977.16977.3 2.35E-10 27/72 K.QTIDNSQGAYQEAFDISKK.E sp|P27348|1433T_HUMAN 1 2142.0229 1.1 103460 16977 3 2142.030585 715.0149 14-3-3 protein theta OS=Homo sapiens OX=9606 GN=YWHAQ PE=1 SV=1 4.56 2857.3 - 1.59E+06 - - - 3.5751 - 4.055 0.605 - 1161.5 1 2 0 0.0077 19 0 0 0 8.49E+07 7.73E+07 - - - 8.7224 1 221125_WJC_METTL3_EV_vs_WT_F07.16978.16978.4 3.96E-07 14/108 R.GLLQDDAHPTLVTYADHSK[136.11].L "sp|Q86U44|MTA70_HUMAN,tr|F5H6D8|F5H6D8_HUMAN,tr|H0YFV6|H0YFV6_HUMAN,tr|B4DTN4|B4DTN4_HUMAN" 4 2088.0367 0.03 103461 16978 4 2088.032667 523.0165 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 5.13 2857.3 - 5.70E+06 - - - -1.9473 - 2.814 0.544 - 206.7 1 2 0 -0.0041 19 0 0 0 1.07E+07 3.53E+08 - - - 4.3098 0.9999 221125_WJC_METTL3_EV_vs_WT_F07.16983.16983.3 4.02E-07 17/52 K.NKLEGLEDALQKAK.Q "sp|P48668|K2C6C_HUMAN,sp|P04259|K2C6B_HUMAN,sp|P02538|K2C6A_HUMAN" 3 1555.857 10.62 103466 16983 3 1555.858951 519.6263 "Keratin, type II cytoskeletal 6C OS=Homo sapiens OX=9606 GN=KRT6C PE=1 SV=3" 6.18 2857.9 - 509952 - - - 1.272 - 2.777 0.496 - 252.6 1 2 2 0.002 14 0 0 0 6.30E+06 5.94E+05 - - - 6.7837 1 221125_WJC_METTL3_EV_vs_WT_F07.16991.16991.3 1.37E-07 18/80 R.C[160.03]ESAPGC[160.03]GVWQRPVIDNPNYK.G "sp|P27824|CALX_HUMAN,tr|A0A7P0T937|A0A7P0T937_HUMAN,tr|A0A7P0T840|A0A7P0T840_HUMAN,tr|A0A7P0TB65|A0A7P0TB65_HUMAN,tr|A0A7P0TAE9|A0A7P0TAE9_HUMAN,tr|D6RGY2|D6RGY2_HUMAN,tr|A0A7P0T8G1|A0A7P0T8G1_HUMAN,tr|A0A7P0Z4D6|A0A7P0Z4D6_HUMAN,tr|A0A7P0Z484|A0A7P0Z484_HUMAN,tr|A0A7P0TAR9|A0A7P0TAR9_HUMAN,tr|A0A7P0T9L0|A0A7P0T9L0_HUMAN" 11 2446.1158 1.34 103472 16991 3 2446.117825 816.3792 Calnexin OS=Homo sapiens OX=9606 GN=CANX PE=1 SV=2 6.05 2859 - 3.16E+06 - - - 0.8283 - 2.934 0.613 - 280.5 1 2 0 0.002 21 0 0 0 4.83E+08 3.61E+08 - - - 7.9543 0.9999 221125_WJC_METTL3_EV_vs_WT_F07.16992.16992.3 0.000287 15/68 K.K[136.11]TDPSSLGATSASFNFGK[136.11].K sp|Q9UKX7|NUP50_HUMAN 1 1829.913 1.53 103473 16992 3 1829.914824 610.9783 Nuclear pore complex protein Nup50 OS=Homo sapiens OX=9606 GN=NUP50 PE=1 SV=2 8.59 2859.1 - 2.08E+06 - - - 0.9733 - 2.141 0.419 - 209.7 1 2 0 0.0018 18 0 0 0 1.06E+08 6.97E+07 - - - 5.1066 1 221125_WJC_METTL3_EV_vs_WT_F07.16993.16993.3 2.10E-07 16/80 R.C[160.03]ESAPGC[160.03]GVWQR[166.11]PVIDNPNYK[136.11].G "sp|P27824|CALX_HUMAN,tr|A0A7P0T937|A0A7P0T937_HUMAN,tr|A0A7P0T840|A0A7P0T840_HUMAN,tr|A0A7P0TB65|A0A7P0TB65_HUMAN,tr|A0A7P0TAE9|A0A7P0TAE9_HUMAN,tr|D6RGY2|D6RGY2_HUMAN,tr|A0A7P0T8G1|A0A7P0T8G1_HUMAN,tr|A0A7P0Z4D6|A0A7P0Z4D6_HUMAN,tr|A0A7P0Z484|A0A7P0Z484_HUMAN,tr|A0A7P0TAR9|A0A7P0TAR9_HUMAN,tr|A0A7P0T9L0|A0A7P0T9L0_HUMAN" 11 2464.1383 1.34 103474 16993 3 2464.137988 822.3867 Calnexin OS=Homo sapiens OX=9606 GN=CANX PE=1 SV=2 6.05 2859.1 - 3.31E+06 - - - -0.114 - 2.843 0.604 - 210.2 1 2 0 -0.0003 21 0 0 0 4.84E+08 3.61E+08 - - - 7.7789 1 221125_WJC_METTL3_EV_vs_WT_F07.16995.16995.4 5.90E-12 23/102 R.EALLSSAVDHGSDEVK[136.11]FR[166.11].Q "sp|P78371|TCPB_HUMAN,tr|F8VQ14|F8VQ14_HUMAN,tr|F5GWF6|F5GWF6_HUMAN" 3 1976.9922 0.35 103476 16995 4 1976.989553 495.2553 T-complex protein 1 subunit beta OS=Homo sapiens OX=9606 GN=CCT2 PE=1 SV=4 4.75 2859.4 - 1.10E+06 - - - -1.3591 - 4.766 0.633 - 641.3 1 2 1 -0.0027 18 0 0 0 3.53E+06 1.01E+07 - - - 5.2698 1 221125_WJC_METTL3_EV_vs_WT_F07.16996.16996.3 4.35E-08 25/76 R.AQTLPTSVVTITSESSPGK[136.11]R[166.11].E "sp|Q01082|SPTB2_HUMAN,tr|A0A087WUZ3|A0A087WUZ3_HUMAN" 2 2076.1182 1.4 103477 16996 3 2076.12008 693.0467 "Spectrin beta chain, non-erythrocytic 1 OS=Homo sapiens OX=9606 GN=SPTBN1 PE=1 SV=2" 8.79 2859.5 - 1.07E+06 - - - 0.9209 - 3.865 0.562 - 768.2 1 2 0 0.0019 20 0 0 0 6.06E+07 4.32E+07 - - - 8.0851 1 221125_WJC_METTL3_EV_vs_WT_F07.16998.16998.3 1.40E-07 17/80 K.QLSQTQSQQQVQEAEGALASK.S sp|Q9HCS4|TF7L1_HUMAN 1 2258.1139 2.39 103479 16998 3 2258.111209 753.7119 Transcription factor 7-like 1 OS=Homo sapiens OX=9606 GN=TCF7L1 PE=2 SV=1 4.53 2859.8 - 584154 - - - -1.1775 - 3.757 0.61 - 400.4 1 2 0 -0.0027 21 0 0 0 6.78E+06 2.84E+06 - - - 8.5135 0.9999 221125_WJC_METTL3_EV_vs_WT_F07.16999.16999.3 0.000726 15/64 R.LKEDQQTVLKPQFYEIK.A sp|Q9BSC4|NOL10_HUMAN 1 2106.1361 0.85 103480 16999 3 2106.136266 703.0526 Nucleolar protein 10 OS=Homo sapiens OX=9606 GN=NOL10 PE=1 SV=1 6.18 2859.9 - 574640 - - - 0.0755 - 3.403 0.475 - 283.9 1 2 1 0.0002 17 0 0 0 4.54E+06 5.35E+06 - - - 6.9296 0.9899 221125_WJC_METTL3_EV_vs_WT_F07.17001.17001.3 0.0761 Nov-64 R.LK[136.11]EDQQTVLK[136.11]PQFYEIK[136.11].A sp|Q9BSC4|NOL10_HUMAN 1 2130.1787 0.85 103482 17001 3 2130.172107 711.0668 Nucleolar protein 10 OS=Homo sapiens OX=9606 GN=NOL10 PE=1 SV=1 6.18 2860.1 - 356343 - - - -3.0983 - 2.167 0.292 - 132.1 1 2 1 -0.0066 17 0 0 0 4.54E+06 5.35E+06 - - - 3.7474 1 221125_WJC_METTL3_EV_vs_WT_F07.17005.17005.3 3.08E-08 23/76 R.AQTLPTSVVTITSESSPGKR.E "sp|Q01082|SPTB2_HUMAN,tr|A0A087WUZ3|A0A087WUZ3_HUMAN" 2 2058.0957 1.41 103484 17005 3 2058.096358 687.0392 "Spectrin beta chain, non-erythrocytic 1 OS=Homo sapiens OX=9606 GN=SPTBN1 PE=1 SV=2" 8.79 2860.7 - 2.46E+06 - - - 0.3207 - 3.579 0.567 - 292.3 1 2 0 0.0007 20 0 0 0 6.06E+07 4.30E+07 - - - 7.9547 1 221125_WJC_METTL3_EV_vs_WT_F07.17007.17007.4 4.27E-11 27/138 R.IVSR[166.11]PEELR[166.11]EDDVGTGAGLLEIK[136.11]K[136.11].L "sp|P49368|TCPG_HUMAN,tr|B4DUR8|B4DUR8_HUMAN" 2 2659.463 0.19 103486 17007 4 2659.46325 665.873 T-complex protein 1 subunit gamma OS=Homo sapiens OX=9606 GN=CCT3 PE=1 SV=4 4.66 2860.8 - 2.84E+06 - - - 0.0808 - 4.596 0.689 - 469.2 1 2 1 0.0002 24 0 0 0 9.67E+06 5.18E+07 - - - 5.7125 0.9999 221125_WJC_METTL3_EV_vs_WT_F07.17013.17013.3 0.000165 Nov-60 R.AELHPVELKPFQDYQK.L sp|P48634|PRC2A_HUMAN 1 1940.9996 2.05 103492 17013 3 1940.99644 648.0071 Protein PRRC2A OS=Homo sapiens OX=9606 GN=PRRC2A PE=1 SV=3 5.45 2861.6 - 383831 - - - -1.6347 - 2.739 0.444 - 135.8 1 2 0 -0.0032 16 0 0 0 1.29E+07 6.27E+06 - - - 6.0746 1 221125_WJC_METTL3_EV_vs_WT_F07.17018.17018.3 1.41E-07 24/88 K.IGGDAATTVNNSTPDFGFGGQKR.Q "sp|Q92945|FUBP2_HUMAN,tr|M0R0I5|M0R0I5_HUMAN,tr|M0R0C6|M0R0C6_HUMAN,tr|A0A087WTP3|A0A087WTP3_HUMAN" 4 2309.1036 1.11 103495 17018 3 2309.10407 770.7085 Far upstream element-binding protein 2 OS=Homo sapiens OX=9606 GN=KHSRP PE=1 SV=4 5.96 2862.2 - 1.35E+06 - - - 0.1875 - 4.354 0.606 - 486.8 1 2 0 0.0004 23 0 0 0 5.19E+07 4.69E+07 - - - 8.7473 1 221125_WJC_METTL3_EV_vs_WT_F07.17019.17019.4 8.28E-07 18/132 K.VGPYHNPQETYHYYQLPVC[160.03]C[160.03]PEK[136.11].L "sp|O15321|TM9S1_HUMAN,tr|E9PJC4|E9PJC4_HUMAN,tr|E9PSI1|E9PSI1_HUMAN,tr|E9PL78|E9PL78_HUMAN,tr|E9PJM1|E9PJM1_HUMAN,tr|E9PS99|E9PS99_HUMAN,tr|E9PQY7|E9PQY7_HUMAN,tr|E9PMQ9|E9PMQ9_HUMAN" 8 2886.2985 1.35 103496 17019 4 2886.298366 722.5819 Transmembrane 9 superfamily member 1 OS=Homo sapiens OX=9606 GN=TM9SF1 PE=2 SV=2 6 2862.4 - 791520 - - - -0.0537 - 2.782 0.537 - 174.7 1 2 0 -0.0002 23 0 0 0 2.02E+07 1.50E+07 - - - 4.2315 1 221125_WJC_METTL3_EV_vs_WT_F07.17023.17023.3 1.36E-08 15/84 K.TVGFGTNNSEHITYLEHNPYEK[136.11].F sp|Q99459|CDC5L_HUMAN 1 2557.1965 1.36 103500 17023 3 2557.191946 853.4061 Cell division cycle 5-like protein OS=Homo sapiens OX=9606 GN=CDC5L PE=1 SV=2 5.31 2862.8 - 776552 - - - -1.7738 - 2.73 0.618 - 242.9 1 2 0 -0.0045 22 0 0 0 2.02E+07 1.48E+07 - - - 7.8099 0.9379 221125_WJC_METTL3_EV_vs_WT_F07.17025.17025.2 0.000326 Aug-32 H.GSSSSLNLGGLTNGSGR.Y "sp|Q14671|PUM1_HUMAN,tr|Q5T1Z8|Q5T1Z8_HUMAN,tr|H0YDK8|H0YDK8_HUMAN,tr|Q5T1Z4|Q5T1Z4_HUMAN,tr|E9PR38|E9PR38_HUMAN" 5 1562.7649 999 103502 17025 2 1562.768829 782.3897 Pumilio homolog 1 OS=Homo sapiens OX=9606 GN=PUM1 PE=1 SV=3 9.75 2863.1 - 288781 - - - 2.5384 - 1.816 0.4 - 148.1 1 1 0 0.004 17 0 0 0 1.64E+06 0.00E+00 - - - 3.461 1 221125_WJC_METTL3_EV_vs_WT_F07.17030.17030.3 5.72E-16 20/88 K.ERPTPSLNNNC[160.03]TTSEDSLVLYNR.V "sp|P07814|SYEP_HUMAN,tr|V9GYZ6|V9GYZ6_HUMAN" 2 2679.2559 0.97 103506 17030 3 2679.250153 894.0926 Bifunctional glutamate\proline--tRNA ligase OS=Homo sapiens OX=9606 GN=EPRS1 PE=1 SV=5 4.68 2863.6 - 587228 - - - -2.1293 - 3.933 0.766 - 497.8 1 2 0 -0.0057 23 0 0 0 2.01E+07 2.08E+07 - - - 10.2911 1 221125_WJC_METTL3_EV_vs_WT_F07.17031.17031.2 2.11E-09 19/30 K.DTFEHDPSESIDEFNK.S "sp|Q9NYF8|BCLF1_HUMAN,tr|E9PKI6|E9PKI6_HUMAN,tr|A0A1W2PQ43|A0A1W2PQ43_HUMAN,tr|E9PK91|E9PK91_HUMAN,tr|E9PJA7|E9PJA7_HUMAN,tr|E9PK09|E9PK09_HUMAN,tr|E9PQN2|E9PQN2_HUMAN" 7 1908.8014 4.1 103507 17031 2 1908.799673 955.408 Bcl-2-associated transcription factor 1 OS=Homo sapiens OX=9606 GN=BCLAF1 PE=1 SV=2 4.01 2863.7 - 467893 - - - -0.8875 - 3.645 0.731 - 1204.9 1 2 0 -0.0017 16 0 0 0 1.04E+07 2.54E+06 - - - 7.6194 1 221125_WJC_METTL3_EV_vs_WT_F07.17033.17033.2 1.02E-10 18/34 K.KTDPSSLGATSASFNFGK.K sp|Q9UKX7|NUP50_HUMAN 1 1813.8846 1.26 103509 17033 2 1813.887593 907.9496 Nuclear pore complex protein Nup50 OS=Homo sapiens OX=9606 GN=NUP50 PE=1 SV=2 8.59 2863.9 - 286835 - - - 1.6263 - 4.124 0.714 - 993.5 1 2 0 0.0029 18 0 0 0 2.27E+06 1.80E+06 - - - 7.797 1 221125_WJC_METTL3_EV_vs_WT_F07.17036.17036.3 5.65E-13 30/88 K.IGGDAATTVNNSTPDFGFGGQK[136.11]R[166.11].Q "sp|Q92945|FUBP2_HUMAN,tr|M0R0I5|M0R0I5_HUMAN,tr|M0R0C6|M0R0C6_HUMAN,tr|A0A087WTP3|A0A087WTP3_HUMAN" 4 2327.1261 1.1 103511 17036 3 2327.125492 776.716 Far upstream element-binding protein 2 OS=Homo sapiens OX=9606 GN=KHSRP PE=1 SV=4 5.96 2864.3 - 2.27E+06 - - - -0.2643 - 5.044 0.702 - 762.9 1 2 0 -0.0006 23 0 0 0 5.19E+07 4.70E+07 - - - 10.1626 1 221125_WJC_METTL3_EV_vs_WT_F07.17038.17038.3 7.20E-11 18/60 K.DTFEHDPSESIDEFNK.S "sp|Q9NYF8|BCLF1_HUMAN,tr|E9PKI6|E9PKI6_HUMAN,tr|A0A1W2PQ43|A0A1W2PQ43_HUMAN,tr|E9PK91|E9PK91_HUMAN,tr|E9PJA7|E9PJA7_HUMAN,tr|E9PK09|E9PK09_HUMAN,tr|E9PQN2|E9PQN2_HUMAN" 7 1908.8014 2.34 103512 17038 3 1908.802001 637.2744 Bcl-2-associated transcription factor 1 OS=Homo sapiens OX=9606 GN=BCLAF1 PE=1 SV=2 4.01 2864.5 - 1.10E+07 - - - 0.3321 - 3.22 0.736 - 473.4 1 2 0 0.0006 16 0 0 0 2.43E+08 1.04E+08 - - - 9.746 1 221125_WJC_METTL3_EV_vs_WT_F07.17039.17039.3 0.000283 16/60 K.DTFEHDPSESIDEFNK[136.11].S "sp|Q9NYF8|BCLF1_HUMAN,tr|E9PKI6|E9PKI6_HUMAN,tr|A0A1W2PQ43|A0A1W2PQ43_HUMAN,tr|E9PK91|E9PK91_HUMAN,tr|E9PJA7|E9PJA7_HUMAN,tr|E9PK09|E9PK09_HUMAN,tr|E9PQN2|E9PQN2_HUMAN" 7 1916.8156 2.34 103513 17039 3 1916.813435 639.9458 Bcl-2-associated transcription factor 1 OS=Homo sapiens OX=9606 GN=BCLAF1 PE=1 SV=2 4.01 2864.6 - 4.61E+06 - - - -1.1123 - 3.25 0.639 - 307.6 1 2 0 -0.0021 16 0 0 0 2.43E+08 1.04E+08 - - - 8.6879 0.9973 221125_WJC_METTL3_EV_vs_WT_F07.17042.17042.3 0.0297 Aug-36 K.GNKPWISLPR.G "sp|P62701|RS4X_HUMAN,sp|P22090|RS4Y1_HUMAN,sp|Q8TD47|RS4Y2_HUMAN,tr|C9JEH7|C9JEH7_HUMAN" 4 1166.656 0.9 103516 17042 3 1166.65533 389.8926 "40S ribosomal protein S4, X isoform OS=Homo sapiens OX=9606 GN=RPS4X PE=1 SV=2" 11 2864.9 - 357534 - - - -0.5974 - 1.686 0.231 - 84.9 1 2 0 -0.0007 10 0 0 0 6.06E+06 6.74E+06 - - - 2.6407 1 221125_WJC_METTL3_EV_vs_WT_F07.17046.17046.3 1.53E-13 22/88 K.ER[166.11]PTPSLNNNC[160.03]TTSEDSLVLYNR[166.11].V "sp|P07814|SYEP_HUMAN,tr|V9GYZ6|V9GYZ6_HUMAN" 2 2699.2724 0.97 103518 17046 3 2699.27214 900.7647 Bifunctional glutamate\proline--tRNA ligase OS=Homo sapiens OX=9606 GN=EPRS1 PE=1 SV=5 4.68 2865.6 - 1.12E+06 - - - -0.0956 - 4.398 0.766 - 642 1 2 0 -0.0003 23 0 0 0 2.01E+07 2.08E+07 - - - 10.5548 0.9997 221125_WJC_METTL3_EV_vs_WT_F07.17053.17053.4 0.00191 14/132 K.GVTIPYRPKPSSSPVIFAGGQDR.Y "sp|Q15366|PCBP2_HUMAN,tr|H3BSS4|H3BSS4_HUMAN" 2 2428.2863 1.08 103523 17053 4 2428.288312 608.0788 Poly(rC)-binding protein 2 OS=Homo sapiens OX=9606 GN=PCBP2 PE=1 SV=1 9.99 2866.3 - 4.51E+06 - - - 0.8315 - 2.252 0.366 - 101.4 1 2 0 0.002 23 0 0 0 1.08E+08 9.97E+07 - - - 2.6741 0.9999 221125_WJC_METTL3_EV_vs_WT_F07.17060.17060.4 5.01E-06 17/132 K.VGPYHNPQETYHYYQLPVC[160.03]C[160.03]PEK.L "sp|O15321|TM9S1_HUMAN,tr|E9PJC4|E9PJC4_HUMAN,tr|E9PSI1|E9PSI1_HUMAN,tr|E9PL78|E9PL78_HUMAN,tr|E9PJM1|E9PJM1_HUMAN,tr|E9PS99|E9PS99_HUMAN,tr|E9PQY7|E9PQY7_HUMAN,tr|E9PMQ9|E9PMQ9_HUMAN" 8 2878.2843 1.35 103528 17060 4 2878.283154 720.5784 Transmembrane 9 superfamily member 1 OS=Homo sapiens OX=9606 GN=TM9SF1 PE=2 SV=2 6 2867.2 - 1.32E+06 - - - -0.4054 - 3.126 0.456 - 175.1 1 2 0 -0.0012 23 0 0 0 2.02E+07 1.50E+07 - - - 3.564 1 221125_WJC_METTL3_EV_vs_WT_F07.17063.17063.3 3.45E-10 19/88 K.GVTIPYRPKPSSSPVIFAGGQDR.Y "sp|Q15366|PCBP2_HUMAN,tr|H3BSS4|H3BSS4_HUMAN" 2 2428.2863 1.05 103531 17063 3 2428.279173 810.436 Poly(rC)-binding protein 2 OS=Homo sapiens OX=9606 GN=PCBP2 PE=1 SV=1 9.99 2867.5 - 652346 - - - -2.9321 - 3.387 0.632 - 293 1 2 0 -0.0071 23 0 0 0 1.63E+07 1.55E+07 - - - 8.4461 0.9996 221125_WJC_METTL3_EV_vs_WT_F07.17070.17070.3 0.00859 Aug-36 K.GNK[136.11]PWISLPR[166.11].G "sp|P62701|RS4X_HUMAN,sp|P22090|RS4Y1_HUMAN,sp|Q8TD47|RS4Y2_HUMAN,tr|C9JEH7|C9JEH7_HUMAN" 4 1184.6785 0.96 103536 17070 3 1184.678237 395.9001 "40S ribosomal protein S4, X isoform OS=Homo sapiens OX=9606 GN=RPS4X PE=1 SV=2" 11 2868.3 - 392782 - - - -0.2195 - 1.813 0.336 - 70.4 1 2 0 -0.0003 10 0 0 0 5.97E+06 6.25E+06 - - - 4.0236 1 221125_WJC_METTL3_EV_vs_WT_F07.17074.17074.3 2.17E-11 19/88 K.GVTIPYR[166.11]PK[136.11]PSSSPVIFAGGQDR[166.11].Y "sp|Q15366|PCBP2_HUMAN,tr|H3BSS4|H3BSS4_HUMAN" 2 2456.317 1.05 103537 17074 3 2456.318987 819.7796 Poly(rC)-binding protein 2 OS=Homo sapiens OX=9606 GN=PCBP2 PE=1 SV=1 9.99 2868.9 - 1.10E+06 - - - 0.7955 - 3.443 0.602 - 277.5 1 2 0 0.002 23 0 0 0 1.63E+07 1.55E+07 - - - 8.1516 0.9997 221125_WJC_METTL3_EV_vs_WT_F07.17077.17077.4 1.09E-05 18/114 R.RAFREEFGAEPELAVSAPGR.V "sp|P51570|GALK1_HUMAN,tr|K7ERJ9|K7ERJ9_HUMAN,tr|K7ERN9|K7ERN9_HUMAN,tr|K7EII7|K7EII7_HUMAN" 4 2188.1025 2.39 103540 17077 4 2188.103104 548.0329 Galactokinase OS=Homo sapiens OX=9606 GN=GALK1 PE=1 SV=1 4.95 2869.2 - 412409 - - - 0.2692 - 2.856 0.442 - 226.7 1 2 1 0.0006 20 0 0 0 3.39E+07 1.42E+07 - - - 3.4238 0.8682 221125_WJC_METTL3_EV_vs_WT_F07.17078.17078.4 0.112 8/114 K.ASEAEAPDK[136.11]HGSASFVSLLK[136.11].S sp|Q9NXV6|CARF_HUMAN 1 2059.0557 1.25 103541 17078 4 2059.056312 515.7712 CDKN2A-interacting protein OS=Homo sapiens OX=9606 GN=CDKN2AIP PE=1 SV=3 5.45 2869.3 - 301216 - - - 0.3045 - 1.966 0.146 - 35.5 1 2 1 0.0006 20 0 0 0 6.60E+06 5.28E+06 - - - 0.7226 1 221125_WJC_METTL3_EV_vs_WT_F07.17082.17082.3 5.43E-08 19/52 K.HWPFQVINDGDK[136.11]PK[136.11].V "sp|P0DMV8|HS71A_HUMAN,sp|P0DMV9|HS71B_HUMAN,tr|A0A0G2JIW1|A0A0G2JIW1_HUMAN" 3 1695.8704 0.13 103543 17082 3 1695.873478 566.2974 Heat shock 70 kDa protein 1A OS=Homo sapiens OX=9606 GN=HSPA1A PE=1 SV=1 6.75 2869.9 - 881751 - - - 1.8209 - 3.155 0.535 - 590.9 1 2 0 0.0031 14 0 0 0 8.02E+08 6.23E+09 - - - 7.5573 0.9998 221125_WJC_METTL3_EV_vs_WT_F07.17085.17085.4 4.06E-06 18/114 K.GTFDGDKLGDLKEEGDVMDK.T "sp|Q14671|PUM1_HUMAN,tr|Q5T1Z8|Q5T1Z8_HUMAN,tr|H0YEH2|H0YEH2_HUMAN,tr|Q5T1Z4|Q5T1Z4_HUMAN" 4 2167.9943 2.62 103546 17085 4 2167.991368 543.0059 Pumilio homolog 1 OS=Homo sapiens OX=9606 GN=PUM1 PE=1 SV=3 4.09 2870.1 - 905620 - - - -1.3658 - 3.185 0.449 - 152.4 1 2 2 -0.003 20 0 0 0 1.11E+08 4.23E+07 - - - 3.5206 1 221125_WJC_METTL3_EV_vs_WT_F07.17086.17086.3 3.54E-08 18/72 R.QAATLAEHPDFSPC[160.03]SFQSK.A "sp|P31269|HXA9_HUMAN,tr|A0A669K9T0|A0A669K9T0_HUMAN,tr|A8MVF3|A8MVF3_HUMAN,tr|A0A669KBC8|A0A669KBC8_HUMAN" 4 2119.9633 2.42 103547 17086 3 2119.965228 707.6617 Homeobox protein Hox-A9 OS=Homo sapiens OX=9606 GN=HOXA9 PE=1 SV=4 5.32 2870.3 - 684015 - - - 0.9076 - 3.28 0.517 - 439.5 1 2 0 0.0019 19 0 0 0 1.36E+07 5.64E+06 - - - 7.2218 0.9946 221125_WJC_METTL3_EV_vs_WT_F07.17087.17087.3 0.0122 Oct-64 K.VGKDHTLEDEDVIQIVK.K sp|Q9Y295|DRG1_HUMAN 1 1937.0106 0.38 103548 17087 3 1937.015111 646.6775 Developmentally-regulated GTP-binding protein 1 OS=Homo sapiens OX=9606 GN=DRG1 PE=1 SV=1 4.43 2870.4 - 307474 - - - 2.3433 - 2.16 0.302 - 110.9 1 2 1 0.0045 17 0 0 0 4.83E+06 1.27E+07 - - - 3.8513 0.9998 221125_WJC_METTL3_EV_vs_WT_F07.17092.17092.4 0.000107 Dec-90 R.NLNTSALQLEHEHLIK.L "sp|Q15643|TRIPB_HUMAN,tr|H0YJ97|H0YJ97_HUMAN" 2 1858.9901 1.42 103551 17092 4 1858.989662 465.7548 Thyroid receptor-interacting protein 11 OS=Homo sapiens OX=9606 GN=TRIP11 PE=1 SV=3 6 2870.9 - 811239 - - - -0.2415 - 2.765 0.364 - 108.9 1 2 0 -0.0004 16 0 0 0 1.49E+07 1.05E+07 - - - 2.7524 1 221125_WJC_METTL3_EV_vs_WT_F07.17096.17096.3 6.92E-18 32/96 K.C[160.03]PVPC[160.03]QTQTVC[160.03]VTGPAPC[160.03]PTQTYVK.Y sp|Q5T750|XP32_HUMAN 1 2848.3016 999 103553 17096 3 2848.303633 950.4412 Skin-specific protein 32 OS=Homo sapiens OX=9606 GN=XP32 PE=1 SV=1 7.88 2871.5 - 1.23E+06 - - - 0.7039 - 4.937 0.735 - 1157.6 1 2 0 0.002 25 0 0 0 3.24E+07 0.00E+00 - - - 10.4075 1 221125_WJC_METTL3_EV_vs_WT_F07.17097.17097.4 6.69E-10 20/78 K.HWPFQVINDGDK[136.11]PK[136.11].V "sp|P0DMV8|HS71A_HUMAN,sp|P0DMV9|HS71B_HUMAN,tr|A0A0G2JIW1|A0A0G2JIW1_HUMAN" 3 1695.8704 0.14 103554 17097 4 1695.869473 424.9749 Heat shock 70 kDa protein 1A OS=Homo sapiens OX=9606 GN=HSPA1A PE=1 SV=1 6.75 2871.6 - 780283 - - - -0.5407 - 3.275 0.587 - 301.5 1 2 0 -0.0009 14 0 0 0 2.70E+08 1.91E+09 - - - 4.7667 1 221125_WJC_METTL3_EV_vs_WT_F07.17105.17105.3 1.34E-07 24/76 K.GTFDGDKLGDLKEEGDVMDK.T "sp|Q14671|PUM1_HUMAN,tr|Q5T1Z8|Q5T1Z8_HUMAN,tr|H0YEH2|H0YEH2_HUMAN,tr|Q5T1Z4|Q5T1Z4_HUMAN" 4 2167.9943 2.86 103560 17105 3 2167.992356 723.6721 Pumilio homolog 1 OS=Homo sapiens OX=9606 GN=PUM1 PE=1 SV=3 4.09 2872.6 - 3.34E+06 - - - -0.9101 - 4.364 0.659 - 838.1 1 2 2 -0.002 20 0 0 0 5.57E+07 1.95E+07 - - - 9.4611 0.9993 221125_WJC_METTL3_EV_vs_WT_F07.17107.17107.3 0.001 Nov-48 K.DSINFLDHINGK[136.11]K[136.11].H "sp|Q96NC0|ZMAT2_HUMAN,tr|R4GNG8|R4GNG8_HUMAN,tr|R4GMX9|R4GMX9_HUMAN" 3 1515.8016 0.59 103562 17107 3 1515.806854 506.2745 Zinc finger matrin-type protein 2 OS=Homo sapiens OX=9606 GN=ZMAT2 PE=1 SV=1 6.75 2872.9 - 482559 - - - 3.4384 - 2.363 0.364 - 147.4 1 2 0 0.0052 13 0 0 0 4.81E+06 8.22E+06 - - - 4.9283 0.999 221125_WJC_METTL3_EV_vs_WT_F07.17108.17108.4 0.00412 17/126 R.SDDGVFHIGAAAQDK[136.11]PSAEVLK[136.11].S "sp|Q6BDS2|URFB1_HUMAN,tr|H7C1J4|H7C1J4_HUMAN" 2 2270.1514 1.28 103563 17108 4 2270.155971 568.5451 UHRF1-binding protein 1 OS=Homo sapiens OX=9606 GN=UHRF1BP1 PE=1 SV=1 4.66 2873 - 423235 - - - 2.0241 - 2.464 0.316 - 71.6 1 2 0 0.0046 22 0 0 0 2.38E+07 1.86E+07 - - - 2.2703 0.9996 221125_WJC_METTL3_EV_vs_WT_F07.17114.17114.3 0.00182 Nov-56 K.R[166.11]SLR[166.11]PDPNFDALISK[136.11].L "sp|Q99496|RING2_HUMAN,sp|Q06587|RING1_HUMAN,tr|X6RFN3|X6RFN3_HUMAN" 3 1755.9626 1.62 103567 17114 3 1755.962736 586.3281 E3 ubiquitin-protein ligase RING2 OS=Homo sapiens OX=9606 GN=RNF2 PE=1 SV=1 8.75 2873.8 - 348152 - - - 0.0729 - 1.84 0.35 - 142 1 2 0 0.0001 15 0 0 0 1.03E+07 6.36E+06 - - - 4.0332 0.9999 221125_WJC_METTL3_EV_vs_WT_F07.17118.17118.3 5.69E-11 21/64 R.K[136.11]DENSINGTPDITVEIR[166.11].E sp|P35573|GDE_HUMAN 1 1917.9763 0.69 103571 17118 3 1917.984453 640.3327 Glycogen debranching enzyme OS=Homo sapiens OX=9606 GN=AGL PE=1 SV=3 4.32 2874.1 - 634566 - - - 4.2743 - 3.687 0.538 - 720.5 1 2 0 0.0082 17 0 0 0 6.65E+06 9.61E+06 - - - 7.8323 0.9999 221125_WJC_METTL3_EV_vs_WT_F07.17121.17121.4 0.000368 21/72 R.C[160.03]ILPFDKETGFHR.G "sp|Q9GZT3|SLIRP_HUMAN,tr|H0YJW7|H0YJW7_HUMAN,tr|A0A087WUN7|A0A087WUN7_HUMAN,tr|G3V2S9|G3V2S9_HUMAN,tr|H0YJ40|H0YJ40_HUMAN,tr|G3V4X6|G3V4X6_HUMAN" 6 1618.7926 1.08 103574 17121 4 1618.794633 405.7054 "SRA stem-loop-interacting RNA-binding protein, mitochondrial OS=Homo sapiens OX=9606 GN=SLIRP PE=1 SV=1" 6.74 2874.5 - 206330 - - - 1.2577 - 3.251 0.503 - 606 1 2 1 0.002 13 0 0 0 1.52E+07 1.41E+07 - - - 4.0407 1 221125_WJC_METTL3_EV_vs_WT_F07.17125.17125.3 8.14E-10 24/76 K.GTFDGDK[136.11]LGDLK[136.11]EEGDVMDK[136.11].T "sp|Q14671|PUM1_HUMAN,tr|Q5T1Z8|Q5T1Z8_HUMAN,tr|H0YEH2|H0YEH2_HUMAN,tr|Q5T1Z4|Q5T1Z4_HUMAN" 4 2192.0369 2.85 103577 17125 3 2192.03119 731.6863 Pumilio homolog 1 OS=Homo sapiens OX=9606 GN=PUM1 PE=1 SV=3 4.09 2874.9 - 1.91E+06 - - - -2.6181 - 4.27 0.672 - 801.8 1 2 2 -0.0057 20 0 0 0 5.57E+07 1.96E+07 - - - 9.5522 0.9999 221125_WJC_METTL3_EV_vs_WT_F07.17131.17131.4 8.61E-06 20/72 R.C[160.03]ILPFDK[136.11]ETGFHR[166.11].G "sp|Q9GZT3|SLIRP_HUMAN,tr|H0YJW7|H0YJW7_HUMAN,tr|A0A087WUN7|A0A087WUN7_HUMAN,tr|G3V2S9|G3V2S9_HUMAN,tr|H0YJ40|H0YJ40_HUMAN,tr|G3V4X6|G3V4X6_HUMAN" 6 1636.8151 1.08 103581 17131 4 1636.816071 410.211 "SRA stem-loop-interacting RNA-binding protein, mitochondrial OS=Homo sapiens OX=9606 GN=SLIRP PE=1 SV=1" 6.74 2875.7 - 702336 - - - 0.6134 - 3.441 0.493 - 486.9 1 2 1 0.001 13 0 0 0 1.55E+07 1.44E+07 - - - 3.975 0.9979 221125_WJC_METTL3_EV_vs_WT_F07.17134.17134.3 6.68E-07 19/92 A.SESSGIPERPC[160.03]VLTGTPESIEQAK.R sp|Q96I24|FUBP3_HUMAN 1 2571.2486 91.01 103583 17134 3 2571.252736 858.0902 Far upstream element-binding protein 3 OS=Homo sapiens OX=9606 GN=FUBP3 PE=1 SV=2 4.49 2876 - 683533 - - - 1.5903 - 3.216 0.577 - 243.5 1 1 0 0.0041 24 0 0 0 1.10E+07 1.20E+05 - - - 7.685 1 221125_WJC_METTL3_EV_vs_WT_F07.17135.17135.3 1.22E-07 20/52 K.HWPFQVINDGDKPK.V "sp|P0DMV8|HS71A_HUMAN,sp|P0DMV9|HS71B_HUMAN,tr|A0A0G2JIW1|A0A0G2JIW1_HUMAN" 3 1679.842 0.13 103584 17135 3 1679.845383 560.9546 Heat shock 70 kDa protein 1A OS=Homo sapiens OX=9606 GN=HSPA1A PE=1 SV=1 6.75 2876.1 - 1.29E+06 - - - 2.0198 - 3.723 0.545 - 704.9 1 2 0 0.0034 14 0 0 0 8.02E+08 6.23E+09 - - - 8.1087 0.9998 221125_WJC_METTL3_EV_vs_WT_F07.17136.17136.3 7.71E-06 15/84 K.VK[136.11]EESQLPGTGGPEDVLQPVQR[166.11].A sp|Q02952|AKA12_HUMAN 1 2380.2353 1.04 103585 17136 3 2380.234464 794.4191 A-kinase anchor protein 12 OS=Homo sapiens OX=9606 GN=AKAP12 PE=1 SV=4 4.41 2876.2 - 602814 - - - -0.3613 - 2.837 0.435 - 152.7 1 2 1 -0.0009 22 0 0 0 9.82E+06 9.47E+06 - - - 5.8618 1 221125_WJC_METTL3_EV_vs_WT_F07.17137.17137.4 1.49E-05 20/78 K.HWPFQVINDGDKPK.V "sp|P0DMV8|HS71A_HUMAN,sp|P0DMV9|HS71B_HUMAN,tr|A0A0G2JIW1|A0A0G2JIW1_HUMAN" 3 1679.842 0.14 103586 17137 4 1679.844609 420.9678 Heat shock 70 kDa protein 1A OS=Homo sapiens OX=9606 GN=HSPA1A PE=1 SV=1 6.75 2876.4 - 526142 - - - 1.5591 - 3.398 0.478 - 269.9 1 2 0 0.0026 14 0 0 0 2.70E+08 1.91E+09 - - - 3.831 0.9994 221125_WJC_METTL3_EV_vs_WT_F07.17138.17138.3 3.57E-06 15/52 K.HMNLILC[160.03]DC[160.03]DEFRK.L "sp|P63162|RSMN_HUMAN,sp|P14678|RSMB_HUMAN,tr|J3KRY3|J3KRY3_HUMAN,tr|J3QLE5|J3QLE5_HUMAN,tr|S4R3P3|S4R3P3_HUMAN" 5 1849.8273 0.77 103587 17138 3 1850.832091 617.6164 Small nuclear ribonucleoprotein-associated protein N OS=Homo sapiens OX=9606 GN=SNRPN PE=1 SV=1 5.38 2876.5 - 1.52E+06 - - - 543.1566 - 2.469 0.569 - 350.7 1 2 0 1.0047 14 0 0 0 1.38E+07 1.79E+07 - - - 7.0074 0.9969 221125_WJC_METTL3_EV_vs_WT_F07.17142.17142.3 0.00527 Nov-56 K.RSLRPDPNFDALISK.L "sp|Q99496|RING2_HUMAN,sp|Q06587|RING1_HUMAN,tr|X6RFN3|X6RFN3_HUMAN" 3 1727.9319 1.68 103589 17142 3 1727.939131 576.9846 E3 ubiquitin-protein ligase RING2 OS=Homo sapiens OX=9606 GN=RNF2 PE=1 SV=1 8.75 2876.9 - 466569 - - - 4.2033 - 2.16 0.323 - 136.5 1 2 0 0.0073 15 0 0 0 1.04E+07 6.20E+06 - - - 4.1486 0.9998 221125_WJC_METTL3_EV_vs_WT_F07.17143.17143.3 0.000118 Nov-72 K.TLQVTMPVKPTNDNDEFEK.Q sp|Q9H7E2|TDRD3_HUMAN 1 2205.0623 5.38 103590 17143 3 2205.059703 736.0281 Tudor domain-containing protein 3 OS=Homo sapiens OX=9606 GN=TDRD3 PE=1 SV=1 4.32 2877 - 286261 - - - -1.2 - 2.168 0.375 - 88.3 1 2 0 -0.0026 19 0 0 0 5.89E+06 1.10E+06 - - - 4.6212 0.9093 221125_WJC_METTL3_EV_vs_WT_F07.17145.17145.4 0.0873 Sep-84 R.NSKIEISELNRVIQR.L sp|P04264|K2C1_HUMAN 1 1798.0061 212.03 103592 17145 4 1798.008363 450.5088 "Keratin, type II cytoskeletal 1 OS=Homo sapiens OX=9606 GN=KRT1 PE=1 SV=6" 8.75 2877.2 - 501461 - - - 1.2614 - 2.057 0.159 - 61.2 1 2 2 0.0023 15 0 0 0 7.57E+06 3.57E+04 - - - 0.8674 1 221125_WJC_METTL3_EV_vs_WT_F07.17152.17152.3 1.01E-11 18/84 R.SDDGVFHIGAAAQDKPSAEVLK.S "sp|Q6BDS2|URFB1_HUMAN,tr|H7C1J4|H7C1J4_HUMAN" 2 2254.123 1.03 103597 17152 3 2254.13032 752.3816 UHRF1-binding protein 1 OS=Homo sapiens OX=9606 GN=UHRF1BP1 PE=1 SV=1 4.66 2878 - 361760 - - - 3.258 - 3.14 0.646 - 209.6 1 2 0 0.0073 22 0 0 0 3.68E+06 3.56E+06 - - - 8.453 0.991 221125_WJC_METTL3_EV_vs_WT_F07.17153.17153.3 0.000938 Oct-56 R.NSKIEISELNRVIQR.L sp|P04264|K2C1_HUMAN 1 1798.0061 999 103598 17153 3 1798.01238 600.3426 "Keratin, type II cytoskeletal 1 OS=Homo sapiens OX=9606 GN=KRT1 PE=1 SV=6" 8.75 2878.2 - 324507 - - - 3.4955 - 2.046 0.33 - 112.4 1 2 2 0.0063 15 0 0 0 4.69E+06 0.00E+00 - - - 4.0854 1 221125_WJC_METTL3_EV_vs_WT_F07.17156.17156.3 7.23E-12 23/76 K.IDSIADHVNSAAVNVEEGTK[136.11].N sp|P56962|STX17_HUMAN 1 2076.0215 0.98 103599 17156 3 2076.023024 693.0144 Syntaxin-17 OS=Homo sapiens OX=9606 GN=STX17 PE=1 SV=2 4.31 2878.6 - 1.12E+06 - - - 0.7452 - 3.901 0.608 - 729.8 1 2 0 0.0015 20 0 0 0 1.61E+07 1.65E+07 - - - 8.6206 0.9865 221125_WJC_METTL3_EV_vs_WT_F07.17158.17158.4 6.87E-06 21/96 K.LDK[136.11]AQIHDLVLVGGSTR[166.11].L "sp|P0DMV8|HS71A_HUMAN,sp|P0DMV9|HS71B_HUMAN,tr|V9GZ37|V9GZ37_HUMAN,tr|A0A0G2JIW1|A0A0G2JIW1_HUMAN" 4 1839.0333 0.11 103601 17158 4 1839.036203 460.7656 Heat shock 70 kDa protein 1A OS=Homo sapiens OX=9606 GN=HSPA1A PE=1 SV=1 6.75 2878.8 - 1.44E+06 - - - 1.5693 - 3.64 0.225 - 308.3 1 2 1 0.0029 17 0 0 0 3.96E+06 3.68E+07 - - - 1.6322 1 221125_WJC_METTL3_EV_vs_WT_F07.17160.17160.3 4.93E-09 21/68 R.AASIENVLQDSSPEHC[160.03]GR.G "sp|O60291|MGRN1_HUMAN,tr|K7EPJ5|K7EPJ5_HUMAN" 2 1968.896 2.3 103603 17160 3 1968.903402 657.3059 E3 ubiquitin-protein ligase MGRN1 OS=Homo sapiens OX=9606 GN=MGRN1 PE=1 SV=2 4.65 2879 - 862557 - - - 3.7833 - 4.037 0.638 - 737.2 1 2 0 0.0074 18 0 0 0 2.25E+07 9.80E+06 - - - 9.1259 0.9999 221125_WJC_METTL3_EV_vs_WT_F07.17164.17164.3 0.000477 13/60 K.QSSEDSSHQISALVLR.A sp|Q15276|RABE1_HUMAN 1 1755.8751 1.81 103607 17164 3 1755.875296 586.299 Rab GTPase-binding effector protein 1 OS=Homo sapiens OX=9606 GN=RABEP1 PE=1 SV=2 5.32 2879.5 - 284213 - - - 0.0883 - 1.752 0.442 - 188.4 1 2 0 0.0002 16 0 0 0 9.13E+06 5.05E+06 - - - 4.9066 0.9988 221125_WJC_METTL3_EV_vs_WT_F07.17165.17165.2 4.15E-05 26-Jul K.HWPFQVINDGDK[136.11]PK[136.11].V "sp|P0DMV8|HS71A_HUMAN,sp|P0DMV9|HS71B_HUMAN,tr|A0A0G2JIW1|A0A0G2JIW1_HUMAN" 3 1695.8704 0.08 103608 17165 2 1695.876317 848.9425 Heat shock 70 kDa protein 1A OS=Homo sapiens OX=9606 GN=HSPA1A PE=1 SV=1 6.75 2879.6 - 208227 - - - 3.495 - 1.807 0.492 - 86.4 1 2 0 0.0059 14 0 0 0 7.51E+06 9.77E+07 - - - 4.1578 1 221125_WJC_METTL3_EV_vs_WT_F07.17168.17168.3 6.35E-14 21/76 K.IDSIADHVNSAAVNVEEGTK.N sp|P56962|STX17_HUMAN 1 2068.0073 0.98 103609 17168 3 2068.010539 690.343 Syntaxin-17 OS=Homo sapiens OX=9606 GN=STX17 PE=1 SV=2 4.31 2880 - 889727 - - - 1.5774 - 3.998 0.631 - 441.9 1 2 0 0.0033 20 0 0 0 1.61E+07 1.65E+07 - - - 8.9361 1 221125_WJC_METTL3_EV_vs_WT_F07.17175.17175.3 2.63E-08 Dec-56 K.DHTLEDEDVIQIVK[136.11]K[136.11].- sp|Q9Y295|DRG1_HUMAN 1 1796.9491 0.48 103614 17175 3 1796.946825 599.9903 Developmentally-regulated GTP-binding protein 1 OS=Homo sapiens OX=9606 GN=DRG1 PE=1 SV=1 4.43 2880.9 - 212849 - - - -1.2627 - 2.561 0.548 - 170.5 1 2 0 -0.0023 15 0 0 0 1.23E+06 2.54E+06 - - - 7.1029 0.9994 221125_WJC_METTL3_EV_vs_WT_F07.17177.17177.3 1.15E-08 18/52 K.HWPFQVINDGDKPK[136.11].V "sp|P0DMV8|HS71A_HUMAN,sp|P0DMV9|HS71B_HUMAN,tr|A0A0G2JIW1|A0A0G2JIW1_HUMAN" 3 1687.8562 - 103616 17177 3 1687.864681 563.626 Heat shock 70 kDa protein 1A OS=Homo sapiens OX=9606 GN=HSPA1A PE=1 SV=1 6.75 2881.2 - 805454 - - - 5.0306 - 3.291 0.414 - 495.9 1 2 0 0.0085 14 0 0 0 - - - - - 6.319 0.9985 221125_WJC_METTL3_EV_vs_WT_F07.17179.17179.4 0.00192 18/108 K.R[166.11]FTAQGLPDLNHSQVYAVK[136.11].T sp|Q92900|RENT1_HUMAN 1 2161.1399 1.19 103618 17179 4 2161.144829 541.2923 Regulator of nonsense transcripts 1 OS=Homo sapiens OX=9606 GN=UPF1 PE=1 SV=2 8.6 2881.5 - 467158 - - - 2.2775 - 2.532 0.3 - 174.7 1 2 0 0.0049 19 0 0 0 1.61E+07 1.35E+07 - - - 2.1501 0.9995 221125_WJC_METTL3_EV_vs_WT_F07.17182.17182.3 0.000195 18/76 R.RAFREEFGAEPELAVSAPGR.V "sp|P51570|GALK1_HUMAN,tr|K7ERJ9|K7ERJ9_HUMAN,tr|K7ERN9|K7ERN9_HUMAN,tr|K7EII7|K7EII7_HUMAN" 4 2188.1025 1.41 103621 17182 3 2188.104539 730.3748 Galactokinase OS=Homo sapiens OX=9606 GN=GALK1 PE=1 SV=1 4.95 2881.9 - 335454 - - - 0.925 - 2.591 0.392 - 133.7 1 2 1 0.002 20 0 0 0 1.53E+07 1.08E+07 - - - 5.2195 0.9992 221125_WJC_METTL3_EV_vs_WT_F07.17188.17188.4 0.000369 15/114 R.R[166.11]AFR[166.11]EEFGAEPELAVSAPGR[166.11].V "sp|P51570|GALK1_HUMAN,tr|K7ERJ9|K7ERJ9_HUMAN,tr|K7ERN9|K7ERN9_HUMAN,tr|K7EII7|K7EII7_HUMAN" 4 2218.1273 3.09 103625 17188 4 2218.133267 555.5391 Galactokinase OS=Homo sapiens OX=9606 GN=GALK1 PE=1 SV=1 4.95 2882.6 - 653710 - - - 2.6788 - 2.366 0.439 - 164 1 2 1 0.0059 20 0 0 0 2.84E+07 9.18E+06 - - - 3.3333 0.9999 221125_WJC_METTL3_EV_vs_WT_F07.17192.17192.4 4.91E-06 17/108 K.RFTAQGLPDLNHSQVYAVK.T sp|Q92900|RENT1_HUMAN 1 2143.1174 1.2 103629 17192 4 2143.123289 536.7866 Regulator of nonsense transcripts 1 OS=Homo sapiens OX=9606 GN=UPF1 PE=1 SV=2 8.6 2883.1 - 427171 - - - 2.7306 - 2.353 0.512 - 124.5 1 2 0 0.0059 19 0 0 0 1.67E+07 1.38E+07 - - - 3.9703 1 221125_WJC_METTL3_EV_vs_WT_F07.17194.17194.3 8.26E-15 18/68 R.QAHLC[160.03]VLASNC[160.03]DEPMYVK.L sp|P25398|RS12_HUMAN 1 2133.9646 2.79 103631 17194 3 2133.963924 712.3288 40S ribosomal protein S12 OS=Homo sapiens OX=9606 GN=RPS12 PE=1 SV=3 5.32 2883.4 - 325035 - - - -0.3013 - 4.051 0.694 - 487.5 1 2 0 -0.0006 18 0 0 0 1.48E+07 5.28E+06 - - - 9.7608 0.9999 221125_WJC_METTL3_EV_vs_WT_F07.17197.17197.4 8.26E-12 25/126 K.SKAEAESLYQSKYEELQITAGR.H sp|P04264|K2C1_HUMAN 1 2500.2445 999 103632 17197 4 2500.250941 626.0684 "Keratin, type II cytoskeletal 1 OS=Homo sapiens OX=9606 GN=KRT1 PE=1 SV=6" 4.94 2883.8 - 2.73E+06 - - - 2.5569 - 4.194 0.612 - 363.8 1 2 2 0.0064 22 0 0 0 2.50E+08 0.00E+00 - - - 5.0202 1 221125_WJC_METTL3_EV_vs_WT_F07.17199.17199.3 5.58E-17 26/84 K.SKAEAESLYQSKYEELQITAGR.H sp|P04264|K2C1_HUMAN 1 2500.2445 999 103634 17199 3 2500.247366 834.4221 "Keratin, type II cytoskeletal 1 OS=Homo sapiens OX=9606 GN=KRT1 PE=1 SV=6" 4.94 2884.1 - 623634 - - - 1.1271 - 4.778 0.706 - 882.4 1 2 2 0.0028 22 0 0 0 6.45E+07 0.00E+00 - - - 10.1185 0.9972 221125_WJC_METTL3_EV_vs_WT_F07.17201.17201.3 0.00483 Oct-80 R.TLDKVSLEETAQLPSAPQGSR.A sp|Q9BRP8|PYM1_HUMAN 1 2226.1492 0.66 103636 17201 3 2226.155135 743.057 Partner of Y14 and mago OS=Homo sapiens OX=9606 GN=PYM1 PE=1 SV=1 4.68 2884.3 - 204567 - - - 2.6701 - 2.324 0.36 - 54 1 2 1 0.0059 21 0 0 0 5.32E+06 8.12E+06 - - - 4.5737 0.9993 221125_WJC_METTL3_EV_vs_WT_F07.17204.17204.3 0.0531 13/72 K.DR[166.11]VEISPEQLSAASTEAER[166.11].L "sp|P46736|BRCC3_HUMAN,tr|X6RJS7|X6RJS7_HUMAN,tr|A0A0A0MS96|A0A0A0MS96_HUMAN" 3 2107.0296 8.15 103639 17204 3 2107.029883 703.3505 Lys-63-specific deubiquitinase BRCC36 OS=Homo sapiens OX=9606 GN=BRCC3 PE=1 SV=2 4.25 2884.7 - 175011 - - - 0.1196 - 2.448 0.361 - 219.4 1 2 1 0.0003 19 0 0 0 4.66E+07 5.72E+06 - - - 4.7642 1 221125_WJC_METTL3_EV_vs_WT_F07.17207.17207.4 2.46E-07 23/132 K.AADFQLHTHVNDGTEFGGSIYQK.V sp|Q9Y277|VDAC3_HUMAN 1 2534.1826 1.29 103640 17207 4 2534.186978 634.5529 Voltage-dependent anion-selective channel protein 3 OS=Homo sapiens OX=9606 GN=VDAC3 PE=1 SV=1 5.21 2885.1 - 1.72E+06 - - - 1.7213 - 3.527 0.55 - 412.9 1 2 0 0.0044 23 0 0 0 8.49E+07 6.58E+07 - - - 4.4204 0.9999 221125_WJC_METTL3_EV_vs_WT_F07.17209.17209.4 0.000796 17/108 K.AQPVPHYGVPFKPQIPEAR.T sp|Q9ULW0|TPX2_HUMAN 1 2130.1374 0.72 103642 17209 4 2130.140881 533.5416 Targeting protein for Xklp2 OS=Homo sapiens OX=9606 GN=TPX2 PE=1 SV=2 8.64 2885.4 - 360128 - - - 1.6135 - 2.647 0.414 - 65.2 1 2 0 0.0034 19 0 0 0 1.29E+07 1.79E+07 - - - 3.1578 0.9837 221125_WJC_METTL3_EV_vs_WT_F07.17210.17210.3 0.155 Sep-64 K.LK[136.11]K[136.11]EDIYAVEIVGGATR[166.11].L "sp|P34932|HSP74_HUMAN,tr|A0A087WTS8|A0A087WTS8_HUMAN,tr|A0A087WYC1|A0A087WYC1_HUMAN" 3 1887.0676 0.001 103643 17210 3 1887.0708 630.0298 Heat shock 70 kDa protein 4 OS=Homo sapiens OX=9606 GN=HSPA4 PE=1 SV=4 6.18 2885.5 - 294187 - - - 1.7048 - 2.003 0.221 - 93.9 1 2 1 0.0032 17 0 0 0 0.00E+00 1.41E+07 - - - 2.7579 0.9999 221125_WJC_METTL3_EV_vs_WT_F07.17211.17211.4 3.63E-07 13/96 K.LK[136.11]K[136.11]EDIYAVEIVGGATR[166.11].L "sp|P34932|HSP74_HUMAN,tr|A0A087WTS8|A0A087WTS8_HUMAN,tr|A0A087WYC1|A0A087WYC1_HUMAN" 3 1887.0676 0.05 103644 17211 4 1887.069986 472.7742 Heat shock 70 kDa protein 4 OS=Homo sapiens OX=9606 GN=HSPA4 PE=1 SV=4 6.18 2885.6 - 220282 - - - 1.2734 - 2.85 0.572 - 107.7 1 2 1 0.0024 17 0 0 0 5.66E+05 1.17E+07 - - - 4.5676 0.9987 221125_WJC_METTL3_EV_vs_WT_F07.17212.17212.3 0.000205 Sep-72 K.QSDTPNPPAVPLQVDSTPK.M "sp|Q9BYW2|SETD2_HUMAN,tr|C9JG86|C9JG86_HUMAN" 2 1990.0007 3.72 103645 17212 3 1990.009845 664.3409 Histone-lysine N-methyltransferase SETD2 OS=Homo sapiens OX=9606 GN=SETD2 PE=1 SV=3 4.21 2885.8 - 179015 - - - 4.5779 - 2.112 0.429 - 50.2 1 2 0 0.0091 19 0 0 0 1.36E+07 3.67E+06 - - - 5.1572 1 221125_WJC_METTL3_EV_vs_WT_F07.17218.17218.4 1.53E-08 17/78 K.HMNLILC[160.03]DC[160.03]DEFR[166.11]K[136.11].L "sp|P63162|RSMN_HUMAN,sp|P14678|RSMB_HUMAN,tr|J3KRY3|J3KRY3_HUMAN,tr|J3QLE5|J3QLE5_HUMAN,tr|S4R3P3|S4R3P3_HUMAN" 5 1867.8498 0.87 103649 17218 4 1867.854199 467.9697 Small nuclear ribonucleoprotein-associated protein N OS=Homo sapiens OX=9606 GN=SNRPN PE=1 SV=1 5.38 2886.6 - 404238 - - - 2.3471 - 3.089 0.557 - 298.6 1 2 0 0.0044 14 0 0 0 3.00E+06 3.46E+06 - - - 4.4834 0.9998 221125_WJC_METTL3_EV_vs_WT_F07.17223.17223.3 7.00E-06 19/52 K.LGKDAVEDLESVGK.G sp|P81605|DCD_HUMAN 1 1458.7566 382.72 103653 17223 3 1458.759801 487.2595 Dermcidin OS=Homo sapiens OX=9606 GN=DCD PE=1 SV=2 4.32 2887.2 - 985634 - - - 2.2019 - 3.031 0.527 - 588.5 1 2 1 0.0032 14 0 0 0 1.79E+07 4.69E+04 - - - 7.3616 0.9999 221125_WJC_METTL3_EV_vs_WT_F07.17225.17225.3 7.31E-07 14/92 R.ISSSKGSLGGGFSSGGFSGGSFSR.G "sp|P13645|K1C10_HUMAN,tr|A0A1B0GVI3|A0A1B0GVI3_HUMAN" 2 2209.04 13.79 103654 17225 3 2209.044123 737.3539 "Keratin, type I cytoskeletal 10 OS=Homo sapiens OX=9606 GN=KRT10 PE=1 SV=6" 11 2887.4 - 658415 - - - 1.8782 - 3.064 0.553 - 179.8 1 2 1 0.0041 24 0 0 0 1.58E+07 1.14E+06 - - - 7.3049 0.9996 221125_WJC_METTL3_EV_vs_WT_F07.17226.17226.3 5.17E-06 17/72 K.RFTAQGLPDLNHSQVYAVK.T sp|Q92900|RENT1_HUMAN 1 2143.1174 1 103655 17226 3 2143.127136 715.3798 Regulator of nonsense transcripts 1 OS=Homo sapiens OX=9606 GN=UPF1 PE=1 SV=2 8.6 2887.6 - 433243 - - - 4.5257 - 3.18 0.434 - 310.7 1 2 0 0.0097 19 0 0 0 3.70E+06 3.71E+06 - - - 6.2182 1 221125_WJC_METTL3_EV_vs_WT_F07.17227.17227.4 9.67E-07 24/132 K.AADFQLHTHVNDGTEFGGSIYQK[136.11].V sp|Q9Y277|VDAC3_HUMAN 1 2542.1968 1.29 103656 17227 4 2542.198588 636.5565 Voltage-dependent anion-selective channel protein 3 OS=Homo sapiens OX=9606 GN=VDAC3 PE=1 SV=1 5.21 2887.6 - 3.39E+06 - - - 0.697 - 3.47 0.52 - 368.9 1 2 0 0.0018 23 0 0 0 8.46E+07 6.58E+07 - - - 4.1547 0.975 221125_WJC_METTL3_EV_vs_WT_F07.17228.17228.2 0.0671 14-Jul V.INDGDK[136.11]PK[136.11].V "sp|P0DMV8|HS71A_HUMAN,sp|P0DMV9|HS71B_HUMAN,tr|A0A0G2JIW1|A0A0G2JIW1_HUMAN" 3 901.484 0.1 103657 17228 2 901.483911 451.7493 Heat shock 70 kDa protein 1A OS=Homo sapiens OX=9606 GN=HSPA1A PE=1 SV=1 5.96 2887.7 - 901582 - - - -0.0943 - 1.525 0.388 - 104.2 1 1 0 -0.0001 8 0 0 0 9.05E+06 8.95E+07 - - - 3.1795 1 221125_WJC_METTL3_EV_vs_WT_F07.17229.17229.3 8.12E-14 23/88 K.AADFQLHTHVNDGTEFGGSIYQK.V sp|Q9Y277|VDAC3_HUMAN 1 2534.1826 1.75 103658 17229 3 2534.184982 845.7348 Voltage-dependent anion-selective channel protein 3 OS=Homo sapiens OX=9606 GN=VDAC3 PE=1 SV=1 5.21 2887.9 - 780536 - - - 0.9336 - 4.564 0.592 - 552.9 1 2 0 0.0024 23 0 0 0 1.77E+07 1.01E+07 - - - 8.7012 1 221125_WJC_METTL3_EV_vs_WT_F07.17230.17230.3 5.59E-10 21/72 K.R[166.11]FTAQGLPDLNHSQVYAVK[136.11].T sp|Q92900|RENT1_HUMAN 1 2161.1399 1 103659 17230 3 2161.140937 721.3872 Regulator of nonsense transcripts 1 OS=Homo sapiens OX=9606 GN=UPF1 PE=1 SV=2 8.6 2888 - 425264 - - - 0.4766 - 3.688 0.587 - 461 1 2 0 0.001 19 0 0 0 3.70E+06 3.71E+06 - - - 8.2905 1 221125_WJC_METTL3_EV_vs_WT_F07.17236.17236.3 2.30E-09 18/64 R.RVPATTLYAHFEQANIK.T sp|Q7Z3B4|NUP54_HUMAN 1 1958.0374 3.35 103662 17236 3 1958.042821 653.6864 Nucleoporin p54 OS=Homo sapiens OX=9606 GN=NUP54 PE=1 SV=2 8.6 2888.8 - 384820 - - - 2.7706 - 3.784 0.571 - 489.6 1 2 0 0.0054 17 0 0 0 1.31E+07 3.90E+06 - - - 8.2665 0.9997 221125_WJC_METTL3_EV_vs_WT_F07.17239.17239.3 5.33E-08 Dec-84 K.SRWDETPASQMGGSTPVLTPGK.T sp|O75533|SF3B1_HUMAN 1 2301.1059 1.27 103665 17239 3 2301.098796 768.0426 Splicing factor 3B subunit 1 OS=Homo sapiens OX=9606 GN=SF3B1 PE=1 SV=3 5.79 2889.2 - 266176 - - - -3.1072 - 2.75 0.565 - 120.2 1 2 1 -0.0072 22 0 0 0 4.04E+07 3.19E+07 - - - 7.2355 1 221125_WJC_METTL3_EV_vs_WT_F07.17244.17244.4 2.78E-06 13/108 R.GLLQDDAHPTLVTYADHSK[136.11].L "sp|Q86U44|MTA70_HUMAN,tr|F5H6D8|F5H6D8_HUMAN,tr|H0YFV6|H0YFV6_HUMAN,tr|B4DTN4|B4DTN4_HUMAN" 4 2088.0367 0.08 103668 17244 4 2088.035539 523.0165 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 5.13 2889.8 - 1.54E+06 - - - -0.5718 - 2.524 0.536 - 150.3 1 2 0 -0.0012 19 0 0 0 2.97E+06 3.88E+07 - - - 4.2042 1 221125_WJC_METTL3_EV_vs_WT_F07.17247.17247.3 1.98E-07 14/64 R.R[166.11]VPATTLYAHFEQANIK[136.11].T sp|Q7Z3B4|NUP54_HUMAN 1 1976.0599 3.21 103671 17247 3 1976.063393 659.6939 Nucleoporin p54 OS=Homo sapiens OX=9606 GN=NUP54 PE=1 SV=2 8.6 2890.1 - 245600 - - - 1.7849 - 2.94 0.493 - 163.9 1 2 0 0.0035 17 0 0 0 1.25E+07 3.90E+06 - - - 6.7599 0.9999 221125_WJC_METTL3_EV_vs_WT_F07.17252.17252.4 9.49E-10 18/108 K.AQPVPHYGVPFK[136.11]PQIPEAR[166.11].T sp|Q9ULW0|TPX2_HUMAN 1 2148.1599 0.73 103674 17252 4 2148.161456 538.0473 Targeting protein for Xklp2 OS=Homo sapiens OX=9606 GN=TPX2 PE=1 SV=2 8.64 2890.8 - 699978 - - - 0.7178 - 3.265 0.452 - 226.8 1 2 0 0.0015 19 0 0 0 1.34E+07 1.84E+07 - - - 3.5601 0.9939 221125_WJC_METTL3_EV_vs_WT_F07.17259.17259.4 0.00792 11/102 K.ELTDEEAERLQLEIDQKK.D "sp|Q9Y266|NUDC_HUMAN,tr|A0A0A0MSS4|A0A0A0MSS4_HUMAN,tr|A0A0A0MSU9|A0A0A0MSU9_HUMAN" 3 2186.1067 1.76 103679 17259 4 2186.104484 547.5339 Nuclear migration protein nudC OS=Homo sapiens OX=9606 GN=NUDC PE=1 SV=1 4.25 2891.7 - 646110 - - - -0.994 - 2.268 0.272 - 88.7 1 2 1 -0.0022 18 0 0 0 1.33E+07 7.57E+06 - - - 1.8734 0.9998 221125_WJC_METTL3_EV_vs_WT_F07.17260.17260.4 3.55E-06 13/102 K.ELTDEEAER[166.11]LQLEIDQK[136.11]K[136.11].D "sp|Q9Y266|NUDC_HUMAN,tr|A0A0A0MSS4|A0A0A0MSS4_HUMAN,tr|A0A0A0MSU9|A0A0A0MSU9_HUMAN" 3 2212.1433 2.77 103680 17260 4 2212.143576 554.0431 Nuclear migration protein nudC OS=Homo sapiens OX=9606 GN=NUDC PE=1 SV=1 4.25 2891.8 - 460739 - - - 0.1126 - 2.535 0.466 - 134.6 1 2 1 0.0002 18 0 0 0 2.26E+07 8.15E+06 - - - 3.6006 0.9994 221125_WJC_METTL3_EV_vs_WT_F07.17266.17266.3 8.43E-06 14/64 K.VDTSVHYNIPELQSSSR[166.11].A "sp|Q14687|GSE1_HUMAN,tr|H7C3B5|H7C3B5_HUMAN,tr|H0Y613|H0Y613_HUMAN" 3 1940.9467 2.39 103683 17266 3 1940.938248 647.9895 Genetic suppressor element 1 OS=Homo sapiens OX=9606 GN=GSE1 PE=1 SV=3 5.32 2892.6 - 283252 - - - -4.3747 - 2.695 0.426 - 242 1 2 0 -0.0085 17 0 0 0 4.95E+07 2.07E+07 - - - 5.7917 1 221125_WJC_METTL3_EV_vs_WT_F07.17267.17267.3 2.82E-10 16/72 K.NQDDFEC[160.03]VTTLEGHENEVK.S sp|O76071|CIAO1_HUMAN 1 2262.9699 1 103684 17267 3 2262.973714 755.3306 Probable cytosolic iron-sulfur protein assembly protein CIAO1 OS=Homo sapiens OX=9606 GN=CIAO1 PE=1 SV=1 4.08 2892.7 - 751212 - - - 1.6827 - 3.2 0.694 - 264 1 2 0 0.0038 19 0 0 0 2.73E+07 2.72E+07 - - - 9.134 1 221125_WJC_METTL3_EV_vs_WT_F07.17270.17270.3 1.08E-05 15/64 K.VDTSVHYNIPELQSSSR.A "sp|Q14687|GSE1_HUMAN,tr|H7C3B5|H7C3B5_HUMAN,tr|H0Y613|H0Y613_HUMAN" 3 1930.9385 2.21 103685 17270 3 1930.937647 644.6534 Genetic suppressor element 1 OS=Homo sapiens OX=9606 GN=GSE1 PE=1 SV=3 5.32 2893.1 - 865622 - - - -0.4257 - 2.851 0.527 - 263 1 2 0 -0.0008 17 0 0 0 1.07E+08 4.82E+07 - - - 7.062 0.9999 221125_WJC_METTL3_EV_vs_WT_F07.17271.17271.3 1.84E-05 16/64 K.QQEQLQLQLLQQQHAGK[136.11].Q "sp|Q9H334|FOXP1_HUMAN,tr|C9J5T4|C9J5T4_HUMAN,tr|A0A3B3IRW5|A0A3B3IRW5_HUMAN,tr|G5E965|G5E965_HUMAN,tr|A0A3B3IRS5|A0A3B3IRS5_HUMAN,tr|A0A3B3IST0|A0A3B3IST0_HUMAN,tr|A0A3B3IT14|A0A3B3IT14_HUMAN,tr|A0A3B3ISA4|A0A3B3ISA4_HUMAN,tr|C9J0F0|C9J0F0_HUMAN,tr|A0A3B3IU15|A0A3B3IU15_HUMAN,tr|A0A3B3IUB6|A0A3B3IUB6_HUMAN,tr|A0A3B3IT66|A0A3B3IT66_HUMAN,tr|A0A087X2G3|A0A087X2G3_HUMAN,tr|A0A0B4J2F3|A0A0B4J2F3_HUMAN,tr|A0A3B3IU08|A0A3B3IU08_HUMAN,tr|A0A3B3IST6|A0A3B3IST6_HUMAN,tr|C9IYY1|C9IYY1_HUMAN,tr|A0A3B3IT26|A0A3B3IT26_HUMAN" 18 2025.0847 3.11 103686 17271 3 2025.087552 676.0355 Forkhead box protein P1 OS=Homo sapiens OX=9606 GN=FOXP1 PE=1 SV=1 6.75 2893.2 - 720924 - - - 1.4148 - 2.888 0.432 - 282.1 1 2 0 0.0029 17 0 0 0 1.59E+08 5.12E+07 - - - 6.0349 0.9997 221125_WJC_METTL3_EV_vs_WT_F07.17280.17280.4 0.000733 15/120 K.ETPPTAHLILPEQHMSLAQQK.A "sp|Q8IWZ3|ANKH1_HUMAN,tr|H0Y472|H0Y472_HUMAN,tr|H0Y7Y3|H0Y7Y3_HUMAN,tr|H0Y4P6|H0Y4P6_HUMAN,tr|H0Y785|H0Y785_HUMAN" 5 2368.2209 1.51 103694 17280 4 2368.219426 593.0625 Ankyrin repeat and KH domain-containing protein 1 OS=Homo sapiens OX=9606 GN=ANKHD1 PE=1 SV=1 6.01 2894.3 - 796226 - - - -0.6292 - 2.841 0.344 - 151.8 1 2 0 -0.0015 21 0 0 0 1.84E+08 1.22E+08 - - - 2.565 1 221125_WJC_METTL3_EV_vs_WT_F07.17283.17283.3 2.50E-13 20/84 K.SR[166.11]WDETPASQMGGSTPVLTPGK[136.11].T sp|O75533|SF3B1_HUMAN 1 2319.1284 1.27 103695 17283 3 2319.12745 774.0501 Splicing factor 3B subunit 1 OS=Homo sapiens OX=9606 GN=SF3B1 PE=1 SV=3 5.79 2894.7 - 903569 - - - -0.4165 - 3.811 0.731 - 292.1 1 2 1 -0.001 22 0 0 0 4.04E+07 3.19E+07 - - - 9.8616 0.9999 221125_WJC_METTL3_EV_vs_WT_F07.17284.17284.3 4.76E-06 Dec-48 R.DLNYC[160.03]FSGMSDHR.Y "sp|P55795|HNRH2_HUMAN,sp|P31943|HNRH1_HUMAN,tr|H0YBD7|H0YBD7_HUMAN,tr|H0YB39|H0YB39_HUMAN,tr|H0YBG7|H0YBG7_HUMAN,tr|E9PCY7|E9PCY7_HUMAN,tr|G8JLB6|G8JLB6_HUMAN" 7 1600.6399 1.17 103696 17284 3 1600.644139 534.5539 Heterogeneous nuclear ribonucleoprotein H2 OS=Homo sapiens OX=9606 GN=HNRNPH2 PE=1 SV=1 5.21 2894.8 - 483364 - - - 2.6721 - 2.161 0.596 - 143.5 1 2 0 0.0043 13 0 0 0 9.45E+06 8.06E+06 - - - 7.2729 1 221125_WJC_METTL3_EV_vs_WT_F07.17285.17285.3 1.11E-07 20/60 K.KQC[160.03]ASLQAAIADAEQR.G sp|P48668|K2C6C_HUMAN 1 1758.8683 82.83 103697 17285 3 1758.871288 587.2967 "Keratin, type II cytoskeletal 6C OS=Homo sapiens OX=9606 GN=KRT6C PE=1 SV=3" 6.06 2894.9 - 1.30E+06 - - - 1.7091 - 3.986 0.549 - 597.6 1 2 0 0.003 16 0 0 0 1.75E+08 2.11E+06 - - - 8.208 0.9999 221125_WJC_METTL3_EV_vs_WT_F07.17287.17287.3 0.000221 14/72 K.ETTLQAPQPPQAPQPLQPR[166.11].K tr|F8W6A0|F8W6A0_HUMAN 1 2106.1097 2.83 103699 17287 3 2106.11179 703.0439 Periphilin-1 OS=Homo sapiens OX=9606 GN=PPHLN1 PE=1 SV=1 6.1 2895.2 - 244772 - - - 0.9819 - 2.405 0.464 - 183.2 1 2 0 0.0021 19 0 0 0 3.67E+07 1.30E+07 - - - 5.8685 1 221125_WJC_METTL3_EV_vs_WT_F07.17291.17291.3 3.82E-07 21/64 K.QQEQLQLQLLQQQHAGK.Q "sp|Q9H334|FOXP1_HUMAN,tr|C9J5T4|C9J5T4_HUMAN,tr|A0A3B3IRW5|A0A3B3IRW5_HUMAN,tr|G5E965|G5E965_HUMAN,tr|A0A3B3IRS5|A0A3B3IRS5_HUMAN,tr|A0A3B3IST0|A0A3B3IST0_HUMAN,tr|A0A3B3IT14|A0A3B3IT14_HUMAN,tr|A0A3B3ISA4|A0A3B3ISA4_HUMAN,tr|C9J0F0|C9J0F0_HUMAN,tr|A0A3B3IU15|A0A3B3IU15_HUMAN,tr|A0A3B3IUB6|A0A3B3IUB6_HUMAN,tr|A0A3B3IT66|A0A3B3IT66_HUMAN,tr|A0A087X2G3|A0A087X2G3_HUMAN,tr|A0A0B4J2F3|A0A0B4J2F3_HUMAN,tr|A0A3B3IU08|A0A3B3IU08_HUMAN,tr|A0A3B3IST6|A0A3B3IST6_HUMAN,tr|C9IYY1|C9IYY1_HUMAN,tr|A0A3B3IT26|A0A3B3IT26_HUMAN" 18 2017.0705 3.11 103701 17291 3 2017.070454 673.3641 Forkhead box protein P1 OS=Homo sapiens OX=9606 GN=FOXP1 PE=1 SV=1 6.75 2895.6 - 5.59E+06 - - - -0.0164 - 3.215 0.558 - 734.4 1 2 0 0 17 0 0 0 1.59E+08 5.12E+07 - - - 7.7114 0.9998 221125_WJC_METTL3_EV_vs_WT_F07.17292.17292.4 0.00132 20/120 K.ETPPTAHLILPEQHMSLAQQK[136.11].A "sp|Q8IWZ3|ANKH1_HUMAN,tr|H0Y472|H0Y472_HUMAN,tr|H0Y7Y3|H0Y7Y3_HUMAN,tr|H0Y4P6|H0Y4P6_HUMAN,tr|H0Y785|H0Y785_HUMAN" 5 2376.2351 1.51 103702 17292 4 2376.231688 595.0661 Ankyrin repeat and KH domain-containing protein 1 OS=Homo sapiens OX=9606 GN=ANKHD1 PE=1 SV=1 6.01 2895.8 - 1.25E+06 - - - -1.4426 - 2.977 0.377 - 170.9 1 2 0 -0.0034 21 0 0 0 1.84E+08 1.22E+08 - - - 2.8672 0.9999 221125_WJC_METTL3_EV_vs_WT_F07.17304.17304.4 4.49E-06 14/102 K.ALADLVHSHIQSNELC[160.03]SK[136.11].Q "sp|P22830|HEMH_HUMAN,tr|A0A499FJN5|A0A499FJN5_HUMAN" 2 2029.0142 1.14 103711 17304 4 2029.014402 508.2608 "Ferrochelatase, mitochondrial OS=Homo sapiens OX=9606 GN=FECH PE=1 SV=2" 5.99 2897.2 - 707561 - - - 0.0877 - 3.173 0.409 - 128.1 1 2 0 0.0002 18 0 0 0 3.06E+07 2.68E+07 - - - 3.1814 0.9998 221125_WJC_METTL3_EV_vs_WT_F07.17305.17305.2 2.62E-07 26-Sep K.HWPFQVINDGDKPK.V "sp|P0DMV8|HS71A_HUMAN,sp|P0DMV9|HS71B_HUMAN,tr|A0A0G2JIW1|A0A0G2JIW1_HUMAN" 3 1679.842 0.08 103712 17305 2 1679.842801 840.9283 Heat shock 70 kDa protein 1A OS=Homo sapiens OX=9606 GN=HSPA1A PE=1 SV=1 6.75 2897.3 - 210490 - - - 0.4828 - 1.902 0.448 - 158.8 1 2 0 0.0008 14 0 0 0 6.43E+06 8.28E+07 - - - 3.963 0.9999 221125_WJC_METTL3_EV_vs_WT_F07.17311.17311.4 4.91E-06 15/114 R.EDDR[166.11]VAIHEAMEQQTISIAK[136.11].A "sp|P33992|MCM5_HUMAN,tr|B1AHB1|B1AHB1_HUMAN" 2 2301.139 0.52 103716 17311 4 2301.138618 576.292 DNA replication licensing factor MCM5 OS=Homo sapiens OX=9606 GN=MCM5 PE=1 SV=5 4.5 2898 - 824613 - - - -0.1573 - 2.83 0.528 - 171 1 2 1 -0.0004 20 0 0 0 9.34E+06 1.81E+07 - - - 4.1694 1 221125_WJC_METTL3_EV_vs_WT_F07.17312.17312.3 1.11E-08 17/76 K.QQPPEPEWIGDGESTSPSDK[136.11].V "sp|Q8NE71|ABCF1_HUMAN,tr|A0A0G2JIC2|A0A0G2JIC2_HUMAN,tr|Q5STZ8|Q5STZ8_HUMAN,tr|A0A0G2JJB9|A0A0G2JJB9_HUMAN" 4 2190.9797 1.54 103717 17312 3 2190.974669 731.3338 ATP-binding cassette sub-family F member 1 OS=Homo sapiens OX=9606 GN=ABCF1 PE=1 SV=2 3.83 2898.1 - 694218 - - - -2.2835 - 2.88 0.626 - 269.3 1 2 0 -0.005 20 0 0 0 4.14E+07 2.69E+07 - - - 8.0841 1 221125_WJC_METTL3_EV_vs_WT_F07.17317.17317.4 8.96E-06 15/102 K.ALADLVHSHIQSNELC[160.03]SK.Q "sp|P22830|HEMH_HUMAN,tr|A0A499FJN5|A0A499FJN5_HUMAN" 2 2021 1.14 103720 17317 4 2021.002189 506.2573 "Ferrochelatase, mitochondrial OS=Homo sapiens OX=9606 GN=FECH PE=1 SV=2" 5.99 2898.6 - 2.19E+06 - - - 1.0713 - 2.875 0.481 - 149.5 1 2 0 0.0022 18 0 0 0 3.06E+07 2.68E+07 - - - 3.7738 0.9992 221125_WJC_METTL3_EV_vs_WT_F07.17319.17319.3 7.93E-05 13/52 K.SFFDNISC[160.03]DDNR[166.11]ER[166.11].R "sp|Q8ND56|LS14A_HUMAN,tr|A0A096LP11|A0A096LP11_HUMAN,tr|A0A140TA76|A0A140TA76_HUMAN,tr|A0A0G2JQ95|A0A0G2JQ95_HUMAN" 4 1793.7542 1.02 103721 17319 3 1793.746906 598.9253 Protein LSM14 homolog A OS=Homo sapiens OX=9606 GN=LSM14A PE=1 SV=3 4.23 2898.9 - 1.05E+06 - - - -4.0669 - 2.184 0.565 - 167.2 1 2 1 -0.0073 14 0 0 0 7.97E+08 7.81E+08 - - - 6.9131 0.9998 221125_WJC_METTL3_EV_vs_WT_F07.17323.17323.3 1.50E-06 19/80 K.DLANLEVPHELPTKQDGSGVK.G "sp|Q8WXI9|P66B_HUMAN,tr|A0A0U1RR34|A0A0U1RR34_HUMAN,tr|A0A0U1RRM1|A0A0U1RRM1_HUMAN,tr|A0A0U1RRK3|A0A0U1RRK3_HUMAN" 4 2246.1543 2.08 103723 17323 3 2246.155148 749.7254 Transcriptional repressor p66-beta OS=Homo sapiens OX=9606 GN=GATAD2B PE=1 SV=1 4.75 2899.3 - 1.66E+06 - - - 0.3882 - 3.379 0.44 - 285.1 1 2 1 0.0009 21 0 0 0 3.42E+07 1.65E+07 - - - 6.3644 0.9999 221125_WJC_METTL3_EV_vs_WT_F07.17324.17324.3 8.48E-07 15/76 K.QQPPEPEWIGDGESTSPSDK.V "sp|Q8NE71|ABCF1_HUMAN,tr|A0A0G2JIC2|A0A0G2JIC2_HUMAN,tr|Q5STZ8|Q5STZ8_HUMAN,tr|A0A0G2JJB9|A0A0G2JJB9_HUMAN" 4 2182.9655 1 103724 17324 3 2182.958983 728.6624 ATP-binding cassette sub-family F member 1 OS=Homo sapiens OX=9606 GN=ABCF1 PE=1 SV=2 3.83 2899.4 - 817007 - - - -2.9726 - 2.568 0.547 - 210.8 1 2 0 -0.0065 20 0 0 0 2.54E+07 2.55E+07 - - - 6.9248 0.9999 221125_WJC_METTL3_EV_vs_WT_F07.17325.17325.3 6.74E-09 21/80 K.DLANLEVPHELPTK[136.11]QDGSGVK[136.11].G "sp|Q8WXI9|P66B_HUMAN,tr|A0A0U1RR34|A0A0U1RR34_HUMAN,tr|A0A0U1RRM1|A0A0U1RRM1_HUMAN,tr|A0A0U1RRK3|A0A0U1RRK3_HUMAN" 4 2262.1827 2.08 103725 17325 3 2262.185183 755.0682 Transcriptional repressor p66-beta OS=Homo sapiens OX=9606 GN=GATAD2B PE=1 SV=1 4.75 2899.5 - 815257 - - - 1.1082 - 3.386 0.587 - 320.7 1 2 1 0.0025 21 0 0 0 3.42E+07 1.65E+07 - - - 8.0078 0.9999 221125_WJC_METTL3_EV_vs_WT_F07.17329.17329.4 1.43E-05 13/102 K.GQWFHISDTHVQAVPTTK[136.11].V sp|Q9Y5T5|UBP16_HUMAN 1 2059.0367 1.12 103728 17329 4 2059.037836 515.7664 Ubiquitin carboxyl-terminal hydrolase 16 OS=Homo sapiens OX=9606 GN=USP16 PE=1 SV=1 6.92 2900 - 609570 - - - 0.5643 - 2.787 0.392 - 112.6 1 2 0 0.0012 18 0 0 0 1.28E+07 1.14E+07 - - - 2.9888 0.9833 221125_WJC_METTL3_EV_vs_WT_F07.17331.17331.2 0.00842 16-Oct Q.VINDGDK[136.11]PK[136.11].V "sp|P0DMV8|HS71A_HUMAN,sp|P0DMV9|HS71B_HUMAN,tr|A0A0G2JIW1|A0A0G2JIW1_HUMAN" 3 1000.5524 0.12 103729 17331 2 1000.552278 501.2835 Heat shock 70 kDa protein 1A OS=Homo sapiens OX=9606 GN=HSPA1A PE=1 SV=1 5.93 2900.2 - 4.47E+06 - - - -0.1319 - 1.823 0.387 - 285.6 1 1 0 -0.0001 9 0 0 0 2.00E+07 1.66E+08 - - - 3.6366 0.9962 221125_WJC_METTL3_EV_vs_WT_F07.17332.17332.3 1.07E-08 23/68 K.ALADLVHSHIQSNELC[160.03]SK[136.11].Q "sp|P22830|HEMH_HUMAN,tr|A0A499FJN5|A0A499FJN5_HUMAN" 2 2029.0142 1.18 103730 17332 3 2030.009131 677.3454 "Ferrochelatase, mitochondrial OS=Homo sapiens OX=9606 GN=FECH PE=1 SV=2" 5.99 2900.3 - 1.40E+06 - - - 490.3401 - 3.95 0.521 - 502.3 1 2 0 0.9949 18 0 0 0 2.30E+07 1.95E+07 - - - 7.4937 1 221125_WJC_METTL3_EV_vs_WT_F07.17333.17333.3 1.48E-07 18/52 K.HWPFQVINDGDK[136.11]PK[136.11].V "sp|P0DMV8|HS71A_HUMAN,sp|P0DMV9|HS71B_HUMAN,tr|A0A0G2JIW1|A0A0G2JIW1_HUMAN" 3 1695.8704 0.13 103731 17333 3 1695.871085 566.2974 Heat shock 70 kDa protein 1A OS=Homo sapiens OX=9606 GN=HSPA1A PE=1 SV=1 6.75 2900.4 - 1.75E+08 - - - 0.4098 - 3.003 0.568 - 643.5 1 2 0 0.0007 14 0 0 0 8.01E+08 6.23E+09 - - - 7.7947 1 221125_WJC_METTL3_EV_vs_WT_F07.17334.17334.3 1.76E-05 19/76 R.QQVAFYGQTLGQAQAHSQEQ.- sp|Q96I24|FUBP3_HUMAN 1 2218.0403 - 103732 17334 3 2218.041131 740.354 Far upstream element-binding protein 3 OS=Homo sapiens OX=9606 GN=FUBP3 PE=1 SV=2 5.24 2900.4 - 1.67E+06 - - - 0.3706 - 2.832 0.503 - 352.9 1 2 0 0.0008 20 0 0 0 - - - - - 6.6732 0.9999 221125_WJC_METTL3_EV_vs_WT_F07.17340.17340.3 3.15E-05 21/72 R.LK[136.11]GQEDSLASAVDAATEQK[136.11].T "sp|Q8WUD4|CCD12_HUMAN,tr|J3KR35|J3KR35_HUMAN" 2 1976.0033 1.59 103736 17340 3 1976.00194 659.675 Coiled-coil domain-containing protein 12 OS=Homo sapiens OX=9606 GN=CCDC12 PE=1 SV=1 4.32 2901.2 - 1.22E+06 - - - -0.6958 - 3.644 0.547 - 516.4 1 2 1 -0.0014 19 0 0 0 1.09E+08 6.85E+07 - - - 7.815 1 221125_WJC_METTL3_EV_vs_WT_F07.17343.17343.3 1.43E-10 18/56 K.NK[136.11]DQGTYEDYVEGLR[166.11].V "sp|P60660|MYL6_HUMAN,tr|F8W1R7|F8W1R7_HUMAN,tr|G3V1V0|G3V1V0_HUMAN,tr|B7Z6Z4|B7Z6Z4_HUMAN,tr|F8VZU9|F8VZU9_HUMAN,tr|G8JLA2|G8JLA2_HUMAN,tr|H0YI43|H0YI43_HUMAN,tr|F8W180|F8W180_HUMAN,tr|G3V1Y7|G3V1Y7_HUMAN,tr|J3KND3|J3KND3_HUMAN,tr|F8VPF3|F8VPF3_HUMAN" 11 1803.8394 1.44 103739 17343 3 1803.831405 602.2871 Myosin light polypeptide 6 OS=Homo sapiens OX=9606 GN=MYL6 PE=1 SV=2 4.32 2901.5 - 491002 - - - -4.4472 - 2.941 0.652 - 347.5 1 2 1 -0.008 15 0 0 0 1.06E+09 7.34E+08 - - - 8.6218 1 221125_WJC_METTL3_EV_vs_WT_F07.17347.17347.4 8.99E-08 20/78 K.HWPFQVINDGDK[136.11]PK[136.11].V "sp|P0DMV8|HS71A_HUMAN,sp|P0DMV9|HS71B_HUMAN,tr|A0A0G2JIW1|A0A0G2JIW1_HUMAN" 3 1695.8704 0.14 103742 17347 4 1695.868622 424.9749 Heat shock 70 kDa protein 1A OS=Homo sapiens OX=9606 GN=HSPA1A PE=1 SV=1 6.75 2902 - 5.62E+07 - - - -1.0425 - 3.362 0.593 - 313.1 1 2 0 -0.0018 14 0 0 0 2.70E+08 1.91E+09 - - - 4.8283 1 221125_WJC_METTL3_EV_vs_WT_F07.17349.17349.2 3.55E-09 16/38 R.QQVAFYGQTLGQAQAHSQEQ.- sp|Q96I24|FUBP3_HUMAN 1 2218.0403 - 103743 17349 2 2220.045447 1110.0274 Far upstream element-binding protein 3 OS=Homo sapiens OX=9606 GN=FUBP3 PE=1 SV=2 5.24 2902.2 - 1.18E+06 - - - 904.0133 - 2.796 0.651 - 410.4 1 2 0 2.0051 20 0 0 0 - - - - - 5.7475 0.994 221125_WJC_METTL3_EV_vs_WT_F07.17352.17352.4 5.09E-07 21/114 H.IADVSHFIRPGNALDQESAR.R "sp|Q9Y2L1|RRP44_HUMAN,tr|F2Z2C0|F2Z2C0_HUMAN,tr|G3V1J5|G3V1J5_HUMAN" 3 2195.1083 1 103746 17352 4 2195.107884 549.7844 Exosome complex exonuclease RRP44 OS=Homo sapiens OX=9606 GN=DIS3 PE=1 SV=2 5.38 2902.6 - 856564 - - - -0.2027 - 3.77 0.456 - 433.6 1 1 0 -0.0004 20 0 0 0 1.22E+07 1.22E+07 - - - 3.6386 0.9999 221125_WJC_METTL3_EV_vs_WT_F07.17353.17353.3 1.86E-05 Dec-80 K.ETPPTAHLILPEQHMSLAQQK[136.11].A "sp|Q8IWZ3|ANKH1_HUMAN,tr|H0Y472|H0Y472_HUMAN,tr|H0Y7Y3|H0Y7Y3_HUMAN,tr|H0Y4P6|H0Y4P6_HUMAN,tr|H0Y785|H0Y785_HUMAN" 5 2376.2351 2.7 103747 17353 3 2376.236305 793.0856 Ankyrin repeat and KH domain-containing protein 1 OS=Homo sapiens OX=9606 GN=ANKHD1 PE=1 SV=1 6.01 2902.7 - 523709 - - - 0.5004 - 2.746 0.391 - 111.6 1 2 0 0.0012 21 0 0 0 2.88E+07 1.07E+07 - - - 5.3207 0.9999 221125_WJC_METTL3_EV_vs_WT_F07.17356.17356.3 7.11E-08 13/52 K.SFFDNISC[160.03]DDNRER.R "sp|Q8ND56|LS14A_HUMAN,tr|A0A096LP11|A0A096LP11_HUMAN,tr|A0A140TA76|A0A140TA76_HUMAN,tr|A0A0G2JQ95|A0A0G2JQ95_HUMAN" 4 1773.7377 1.02 103748 17356 3 1773.7362 592.2532 Protein LSM14 homolog A OS=Homo sapiens OX=9606 GN=LSM14A PE=1 SV=3 4.23 2903.1 - 1.44E+07 - - - -0.8237 - 2.17 0.665 - 188.9 1 2 1 -0.0015 14 0 0 0 7.97E+08 7.81E+08 - - - 8.0125 0.9999 221125_WJC_METTL3_EV_vs_WT_F07.17357.17357.4 9.06E-12 22/120 K.LTALDYHNPAGFNC[160.03]K[136.11]DETEFR[166.11].N "sp|Q9Y224|RTRAF_HUMAN,tr|G3V4C6|G3V4C6_HUMAN,tr|G3V4E7|G3V4E7_HUMAN" 3 2515.1557 0.61 103749 17357 4 2515.154431 629.7962 "RNA transcription, translation and transport factor protein OS=Homo sapiens OX=9606 GN=RTRAF PE=1 SV=1" 4.75 2903.2 - 1.13E+06 - - - -0.5018 - 3.583 0.601 - 378.1 1 2 1 -0.0013 21 0 0 0 2.55E+07 4.16E+07 - - - 4.8787 0.9973 221125_WJC_METTL3_EV_vs_WT_F07.17359.17359.2 0.00567 26-Sep K.SFFDNISC[160.03]DDNRER.R "sp|Q8ND56|LS14A_HUMAN,tr|A0A096LP11|A0A096LP11_HUMAN,tr|A0A140TA76|A0A140TA76_HUMAN,tr|A0A0G2JQ95|A0A0G2JQ95_HUMAN" 4 1773.7377 1.17 103751 17359 2 1773.735896 887.8761 Protein LSM14 homolog A OS=Homo sapiens OX=9606 GN=LSM14A PE=1 SV=3 4.23 2903.4 - 605032 - - - -0.9951 - 1.574 0.525 - 95.1 1 2 1 -0.0018 14 0 0 0 4.53E+07 3.87E+07 - - - 4.0564 0.9999 221125_WJC_METTL3_EV_vs_WT_F07.17361.17361.2 2.43E-05 13/38 R.ESTGAQVQVAGDMLPNSTER[166.11].A "sp|P57721|PCBP3_HUMAN,sp|Q15366|PCBP2_HUMAN,sp|Q15365|PCBP1_HUMAN,tr|E9PFP8|E9PFP8_HUMAN,tr|J3QT27|J3QT27_HUMAN,tr|F8VZX2|F8VZX2_HUMAN,tr|F8W0G4|F8W0G4_HUMAN,tr|F8VXH9|F8VXH9_HUMAN,tr|H3BRU6|H3BRU6_HUMAN" 9 2098.9829 0.75 103753 17361 2 2098.981386 1050.4987 Poly(rC)-binding protein 3 OS=Homo sapiens OX=9606 GN=PCBP3 PE=1 SV=2 4.14 2903.7 - 365445 - - - -0.7056 - 2.567 0.537 - 350.3 1 2 0 -0.0015 20 0 0 0 1.20E+07 1.60E+07 - - - 5.3246 0.9991 221125_WJC_METTL3_EV_vs_WT_F07.17362.17362.4 0.0224 15/108 K.HSVPVLPHGDQQYLFSPSR.E "sp|Q9BVV6|TALD3_HUMAN,tr|A0A087WYM5|A0A087WYM5_HUMAN,tr|A0A494C058|A0A494C058_HUMAN,tr|A0A494C0M8|A0A494C0M8_HUMAN,tr|A0A494C075|A0A494C075_HUMAN,tr|A0A494C171|A0A494C171_HUMAN" 6 2163.0861 1.38 103754 17362 4 2163.084688 541.7788 Protein TALPID3 OS=Homo sapiens OX=9606 GN=KIAA0586 PE=1 SV=4 6.92 2903.8 - 334521 - - - -0.6699 - 2.376 0.298 - 155.3 1 2 0 -0.0014 19 0 0 0 1.23E+07 8.93E+06 - - - 2.1121 0.9998 221125_WJC_METTL3_EV_vs_WT_F07.17366.17366.3 0.000319 14/76 K.NPPNQSSNER[166.11]PPSLLVIETK[136.11].K "sp|O15042|SR140_HUMAN,tr|E7EW00|E7EW00_HUMAN,tr|E7ET15|E7ET15_HUMAN,tr|H0Y8D9|H0Y8D9_HUMAN" 4 2237.1771 0.37 103756 17366 3 2237.172925 746.733 U2 snRNP-associated SURP motif-containing protein OS=Homo sapiens OX=9606 GN=U2SURP PE=1 SV=2 6.14 2904.4 - 2.39E+06 - - - -1.8573 - 2.329 0.415 - 209.9 1 2 0 -0.0042 20 0 0 0 2.89E+07 7.72E+07 - - - 5.2167 1 221125_WJC_METTL3_EV_vs_WT_F07.17368.17368.3 2.52E-06 21/76 R.ESTGAQVQVAGDMLPNSTER[166.11].A "sp|P57721|PCBP3_HUMAN,sp|Q15366|PCBP2_HUMAN,sp|Q15365|PCBP1_HUMAN,tr|E9PFP8|E9PFP8_HUMAN,tr|J3QT27|J3QT27_HUMAN,tr|F8VZX2|F8VZX2_HUMAN,tr|F8W0G4|F8W0G4_HUMAN,tr|F8VXH9|F8VXH9_HUMAN,tr|H3BRU6|H3BRU6_HUMAN" 9 2098.9829 0.59 103758 17368 3 2098.98067 700.6682 Poly(rC)-binding protein 3 OS=Homo sapiens OX=9606 GN=PCBP3 PE=1 SV=2 4.14 2904.5 - 1.62E+06 - - - -1.0467 - 3.51 0.561 - 304.8 1 2 0 -0.0022 20 0 0 0 4.49E+07 7.58E+07 - - - 7.8401 0.8589 221125_WJC_METTL3_EV_vs_WT_F07.17370.17370.2 0.164 12-May L.NDGDK[136.11]PK[136.11].V "sp|P0DMV8|HS71A_HUMAN,sp|P0DMV9|HS71B_HUMAN,tr|A0A0G2JIW1|A0A0G2JIW1_HUMAN" 3 788.3999 0.13 103760 17370 2 788.399844 395.2072 Heat shock 70 kDa protein 1A OS=Homo sapiens OX=9606 GN=HSPA1A PE=1 SV=1 5.96 2904.8 - 482190 - - - -0.1116 - 0.93 0.37 - 82.1 1 1 0 -0.0001 7 0 0 0 1.68E+06 1.29E+07 - - - 1.5438 1 221125_WJC_METTL3_EV_vs_WT_F07.17373.17373.3 2.70E-10 16/56 K.NKDQGTYEDYVEGLR.V "sp|P60660|MYL6_HUMAN,tr|F8W1R7|F8W1R7_HUMAN,tr|G3V1V0|G3V1V0_HUMAN,tr|B7Z6Z4|B7Z6Z4_HUMAN,tr|F8VZU9|F8VZU9_HUMAN,tr|G8JLA2|G8JLA2_HUMAN,tr|H0YI43|H0YI43_HUMAN,tr|F8W180|F8W180_HUMAN,tr|G3V1Y7|G3V1Y7_HUMAN,tr|J3KND3|J3KND3_HUMAN,tr|F8VPF3|F8VPF3_HUMAN" 11 1785.817 1.45 103761 17373 3 1785.815504 596.2796 Myosin light polypeptide 6 OS=Homo sapiens OX=9606 GN=MYL6 PE=1 SV=2 4.32 2905.1 - 1.25E+07 - - - -0.8136 - 2.86 0.693 - 304.2 1 2 1 -0.0015 15 0 0 0 1.06E+09 7.35E+08 - - - 9.0078 0.9998 221125_WJC_METTL3_EV_vs_WT_F07.17375.17375.3 1.06E-09 18/72 R.LKGQEDSLASAVDAATEQK.T "sp|Q8WUD4|CCD12_HUMAN,tr|J3KR35|J3KR35_HUMAN" 2 1959.9749 1.59 103763 17375 3 1959.974942 654.3322 Coiled-coil domain-containing protein 12 OS=Homo sapiens OX=9606 GN=CCDC12 PE=1 SV=1 4.32 2905.3 - 4.72E+06 - - - 0.0138 - 3.5 0.405 - 402.1 1 2 1 0 19 0 0 0 1.09E+08 6.85E+07 - - - 6.1331 1 221125_WJC_METTL3_EV_vs_WT_F07.17376.17376.4 7.78E-14 22/120 K.ETTYYDVLGVK[136.11]PNATQEELK[136.11]K[136.11].A sp|P31689|DNJA1_HUMAN 1 2449.2803 0.49 103764 17376 4 2449.281271 613.3273 DnaJ homolog subfamily A member 1 OS=Homo sapiens OX=9606 GN=DNAJA1 PE=1 SV=2 4.87 2905.4 - 2.49E+06 - - - 0.4083 - 3.525 0.622 - 352.4 1 2 0 0.001 21 0 0 0 1.64E+08 3.37E+08 - - - 5.0562 0.9994 221125_WJC_METTL3_EV_vs_WT_F07.17377.17377.3 5.23E-05 15/76 R.ESTGAQVQVAGDMLPNSTER.A "sp|P57721|PCBP3_HUMAN,sp|Q15366|PCBP2_HUMAN,sp|Q15365|PCBP1_HUMAN,tr|E9PFP8|E9PFP8_HUMAN,tr|J3QT27|J3QT27_HUMAN,tr|F8VZX2|F8VZX2_HUMAN,tr|F8W0G4|F8W0G4_HUMAN,tr|F8VXH9|F8VXH9_HUMAN,tr|H3BRU6|H3BRU6_HUMAN" 9 2088.9746 0.63 103765 17377 3 2088.963197 697.3321 Poly(rC)-binding protein 3 OS=Homo sapiens OX=9606 GN=PCBP3 PE=1 SV=2 4.14 2905.4 - 1.73E+06 - - - -5.4572 - 2.58 0.517 - 128.6 1 2 0 -0.0114 20 0 0 0 4.46E+07 7.11E+07 - - - 6.6002 0.9974 221125_WJC_METTL3_EV_vs_WT_F07.17378.17378.2 0.00921 14/26 K.SFFDNISC[160.03]DDNR[166.11]ER[166.11].R "sp|Q8ND56|LS14A_HUMAN,tr|A0A096LP11|A0A096LP11_HUMAN,tr|A0A140TA76|A0A140TA76_HUMAN,tr|A0A0G2JQ95|A0A0G2JQ95_HUMAN" 4 1793.7542 1.17 103766 17378 2 1793.751447 897.8844 Protein LSM14 homolog A OS=Homo sapiens OX=9606 GN=LSM14A PE=1 SV=3 4.23 2905.6 - 1.66E+06 - - - -1.5353 - 2.146 0.483 - 281.2 1 2 1 -0.0028 14 0 0 0 4.53E+07 3.87E+07 - - - 4.5238 0.9999 221125_WJC_METTL3_EV_vs_WT_F07.17383.17383.3 6.45E-08 17/64 R.VQEQELKSEFEQNLSEK.L "sp|Q16891|MIC60_HUMAN,tr|B9A067|B9A067_HUMAN,tr|C9J406|C9J406_HUMAN,tr|H7C463|H7C463_HUMAN" 4 2064.0011 1.74 103769 17383 3 2063.998879 689.0077 MICOS complex subunit MIC60 OS=Homo sapiens OX=9606 GN=IMMT PE=1 SV=1 4.33 2906.2 - 1.40E+06 - - - -1.0901 - 3.153 0.517 - 270.7 1 2 1 -0.0023 17 0 0 0 3.02E+07 1.74E+07 - - - 7.2045 0.9975 221125_WJC_METTL3_EV_vs_WT_F07.17385.17385.2 9.96E-08 19/28 K.NK[136.11]DQGTYEDYVEGLR[166.11].V "sp|P60660|MYL6_HUMAN,tr|F8W1R7|F8W1R7_HUMAN,tr|G3V1V0|G3V1V0_HUMAN,tr|B7Z6Z4|B7Z6Z4_HUMAN,tr|F8VZU9|F8VZU9_HUMAN,tr|G8JLA2|G8JLA2_HUMAN,tr|H0YI43|H0YI43_HUMAN,tr|F8W180|F8W180_HUMAN,tr|G3V1Y7|G3V1Y7_HUMAN,tr|J3KND3|J3KND3_HUMAN,tr|F8VPF3|F8VPF3_HUMAN" 11 1803.8394 1.39 103771 17385 2 1803.835746 902.927 Myosin light polypeptide 6 OS=Homo sapiens OX=9606 GN=MYL6 PE=1 SV=2 4.32 2906.5 - 1.26E+06 - - - -2.0406 - 3.03 0.47 - 756.7 1 2 1 -0.0037 15 0 0 0 5.35E+07 3.84E+07 - - - 5.2367 1 221125_WJC_METTL3_EV_vs_WT_F07.17387.17387.2 1.59E-09 18/28 K.NKDQGTYEDYVEGLR.V "sp|P60660|MYL6_HUMAN,tr|F8W1R7|F8W1R7_HUMAN,tr|G3V1V0|G3V1V0_HUMAN,tr|B7Z6Z4|B7Z6Z4_HUMAN,tr|F8VZU9|F8VZU9_HUMAN,tr|G8JLA2|G8JLA2_HUMAN,tr|H0YI43|H0YI43_HUMAN,tr|F8W180|F8W180_HUMAN,tr|G3V1Y7|G3V1Y7_HUMAN,tr|J3KND3|J3KND3_HUMAN,tr|F8VPF3|F8VPF3_HUMAN" 11 1785.817 1.39 103773 17387 2 1785.813242 893.9158 Myosin light polypeptide 6 OS=Homo sapiens OX=9606 GN=MYL6 PE=1 SV=2 4.32 2906.7 - 823702 - - - -2.0803 - 3.578 0.486 - 1395.5 1 2 1 -0.0037 15 0 0 0 5.35E+07 3.84E+07 - - - 5.7636 1 221125_WJC_METTL3_EV_vs_WT_F07.17389.17389.3 6.06E-10 18/52 K.HWPFQVINDGDKPK.V "sp|P0DMV8|HS71A_HUMAN,sp|P0DMV9|HS71B_HUMAN,tr|A0A0G2JIW1|A0A0G2JIW1_HUMAN" 3 1679.842 0.14 103774 17389 3 1679.842101 560.9546 Heat shock 70 kDa protein 1A OS=Homo sapiens OX=9606 GN=HSPA1A PE=1 SV=1 6.75 2906.9 - 2.70E+07 - - - 0.0661 - 3.1 0.545 - 577 1 2 0 0.0001 14 0 0 0 1.06E+09 7.75E+09 - - - 7.6229 1 221125_WJC_METTL3_EV_vs_WT_F07.17390.17390.4 1.72E-07 16/78 K.HWPFQVINDGDKPK.V "sp|P0DMV8|HS71A_HUMAN,sp|P0DMV9|HS71B_HUMAN,tr|A0A0G2JIW1|A0A0G2JIW1_HUMAN" 3 1679.842 0.14 103775 17390 4 1679.840495 420.9678 Heat shock 70 kDa protein 1A OS=Homo sapiens OX=9606 GN=HSPA1A PE=1 SV=1 6.75 2907 - 8.37E+06 - - - -0.89 - 3.089 0.542 - 172.5 1 2 0 -0.0015 14 0 0 0 2.61E+08 1.81E+09 - - - 4.3536 1 221125_WJC_METTL3_EV_vs_WT_F07.17392.17392.2 6.78E-11 17/28 K.QISNLQQSISDAEQR.G sp|P04264|K2C1_HUMAN 1 1715.8438 999 103777 17392 2 1715.841575 858.9292 "Keratin, type II cytoskeletal 1 OS=Homo sapiens OX=9606 GN=KRT1 PE=1 SV=6" 4.37 2907.2 - 805379 - - - -1.3206 - 3.327 0.571 - 1213.2 1 2 0 -0.0023 15 0 0 0 2.18E+08 0.00E+00 - - - 6.213 1 221125_WJC_METTL3_EV_vs_WT_F07.17395.17395.4 1.23E-07 17/120 K.ETTYYDVLGVKPNATQEELKK.A sp|P31689|DNJA1_HUMAN 1 2425.2377 0.49 103778 17395 4 2425.234963 607.3167 DnaJ homolog subfamily A member 1 OS=Homo sapiens OX=9606 GN=DNAJA1 PE=1 SV=2 4.87 2907.6 - 2.72E+06 - - - -1.1166 - 3.198 0.563 - 161.2 1 2 0 -0.0027 21 0 0 0 1.64E+08 3.37E+08 - - - 4.51 1 221125_WJC_METTL3_EV_vs_WT_F07.17396.17396.3 5.33E-13 22/80 K.ETTYYDVLGVK[136.11]PNATQEELK[136.11]K[136.11].A sp|P31689|DNJA1_HUMAN 1 2449.2803 0.48 103779 17396 3 2449.278055 817.434 DnaJ homolog subfamily A member 1 OS=Homo sapiens OX=9606 GN=DNAJA1 PE=1 SV=2 4.87 2907.8 - 1.18E+06 - - - -0.9048 - 3.859 0.674 - 518 1 2 0 -0.0022 21 0 0 0 3.60E+07 7.47E+07 - - - 9.2914 1 221125_WJC_METTL3_EV_vs_WT_F07.17397.17397.4 3.43E-09 24/120 K.LTALDYHNPAGFNC[160.03]KDETEFR.N "sp|Q9Y224|RTRAF_HUMAN,tr|G3V4C6|G3V4C6_HUMAN,tr|G3V4E7|G3V4E7_HUMAN" 3 2497.1332 0.61 103780 17397 4 2497.128455 625.2906 "RNA transcription, translation and transport factor protein OS=Homo sapiens OX=9606 GN=RTRAF PE=1 SV=1" 4.75 2907.8 - 2.46E+06 - - - -1.9094 - 4.269 0.646 - 448.2 1 2 1 -0.0048 21 0 0 0 2.53E+07 4.14E+07 - - - 5.3273 1 221125_WJC_METTL3_EV_vs_WT_F07.17398.17398.2 3.09E-09 15/38 R.ESTGAQVQVAGDMLPNSTER.A "sp|P57721|PCBP3_HUMAN,sp|Q15366|PCBP2_HUMAN,sp|Q15365|PCBP1_HUMAN,tr|E9PFP8|E9PFP8_HUMAN,tr|J3QT27|J3QT27_HUMAN,tr|F8VZX2|F8VZX2_HUMAN,tr|F8W0G4|F8W0G4_HUMAN,tr|F8VXH9|F8VXH9_HUMAN,tr|H3BRU6|H3BRU6_HUMAN" 9 2088.9746 0.74 103781 17398 2 2088.972623 1045.4946 Poly(rC)-binding protein 3 OS=Homo sapiens OX=9606 GN=PCBP3 PE=1 SV=2 4.14 2908 - 590481 - - - -0.945 - 2.661 0.583 - 489.2 1 2 0 -0.002 20 0 0 0 1.20E+07 1.62E+07 - - - 5.7526 1 221125_WJC_METTL3_EV_vs_WT_F07.17399.17399.3 2.10E-06 13/64 K.K[136.11]VDDDLGTIESLEEAK[136.11]K[136.11].K sp|P35580|MYH10_HUMAN 1 1913.0056 1.11 103782 17399 3 1913.003341 638.6758 Myosin-10 OS=Homo sapiens OX=9606 GN=MYH10 PE=1 SV=3 4.3 2908.1 - 345646 - - - -1.1563 - 2.715 0.446 - 220.4 1 2 0 -0.0022 17 0 0 0 8.40E+06 7.60E+06 - - - 6.0351 1 221125_WJC_METTL3_EV_vs_WT_F07.17402.17402.3 1.36E-07 15/56 K.QISNLQQSISDAEQR.G sp|P04264|K2C1_HUMAN 1 1715.8438 290.49 103783 17402 3 1715.843108 572.9552 "Keratin, type II cytoskeletal 1 OS=Homo sapiens OX=9606 GN=KRT1 PE=1 SV=6" 4.37 2908.5 - 2.92E+06 - - - -0.4272 - 2.822 0.534 - 320.2 1 2 0 -0.0007 15 0 0 0 3.41E+08 1.17E+06 - - - 7.2004 1 221125_WJC_METTL3_EV_vs_WT_F07.17403.17403.4 3.46E-07 20/102 K.FAASGGFLHHMAGLSSSK[136.11].L "sp|Q9BY77|PDIP3_HUMAN,tr|F6VRR5|F6VRR5_HUMAN,tr|F8WCX5|F8WCX5_HUMAN,tr|Q8WUT1|Q8WUT1_HUMAN" 4 1811.8868 1.38 103784 17403 4 1811.883801 453.979 Polymerase delta-interacting protein 3 OS=Homo sapiens OX=9606 GN=POLDIP3 PE=1 SV=2 8.76 2908.6 - 867667 - - - -1.6762 - 3.455 0.497 - 352.7 1 2 0 -0.003 18 0 0 0 1.59E+08 1.15E+08 - - - 3.9758 0.9994 221125_WJC_METTL3_EV_vs_WT_F07.17404.17404.2 4.79E-06 24-Oct R.TTPSYVAFTDTER[166.11].L "sp|P48741|HSP77_HUMAN,sp|P54652|HSP72_HUMAN,sp|P0DMV8|HS71A_HUMAN,sp|P34931|HS71L_HUMAN,sp|P11142|HSP7C_HUMAN,sp|P0DMV9|HS71B_HUMAN,sp|P17066|HSP76_HUMAN,tr|E9PQQ4|E9PQQ4_HUMAN,tr|E9PNE6|E9PNE6_HUMAN,tr|E9PKE3|E9PKE3_HUMAN,tr|E9PLF4|E9PLF4_HUMAN,tr|Q53FA3|Q53FA3_HUMAN,tr|E9PI65|E9PI65_HUMAN,tr|E9PK54|E9PK54_HUMAN,tr|E9PN25|E9PN25_HUMAN,tr|E9PPY6|E9PPY6_HUMAN,tr|E9PQK7|E9PQK7_HUMAN,tr|A0A0G2JIW1|A0A0G2JIW1_HUMAN" 18 1496.7023 0.32 103785 17404 2 1496.698877 749.3584 Putative heat shock 70 kDa protein 7 OS=Homo sapiens OX=9606 GN=HSPA7 PE=5 SV=2 4.37 2908.7 - 2.94E+06 - - - -2.2596 - 2.215 0.381 - 311.4 1 2 0 -0.0034 13 0 0 0 1.71E+07 5.40E+07 - - - 3.895 0.9996 221125_WJC_METTL3_EV_vs_WT_F07.17411.17411.3 6.77E-06 16/64 R.VQEQELK[136.11]SEFEQNLSEK[136.11].L "sp|Q16891|MIC60_HUMAN,tr|B9A067|B9A067_HUMAN,tr|C9J406|C9J406_HUMAN,tr|H7C463|H7C463_HUMAN" 4 2080.0295 1.74 103789 17411 3 2080.025618 694.3505 MICOS complex subunit MIC60 OS=Homo sapiens OX=9606 GN=IMMT PE=1 SV=1 4.33 2909.5 - 818442 - - - -1.8803 - 2.696 0.439 - 221.2 1 2 1 -0.0039 17 0 0 0 3.02E+07 1.74E+07 - - - 5.9388 1 221125_WJC_METTL3_EV_vs_WT_F07.17413.17413.2 1.02E-06 17/26 K.HWPFQVINDGDK[136.11]PK[136.11].V "sp|P0DMV8|HS71A_HUMAN,sp|P0DMV9|HS71B_HUMAN,tr|A0A0G2JIW1|A0A0G2JIW1_HUMAN" 3 1695.8704 0.09 103790 17413 2 1695.867878 848.9425 Heat shock 70 kDa protein 1A OS=Homo sapiens OX=9606 GN=HSPA1A PE=1 SV=1 6.75 2909.7 - 3.01E+06 - - - -1.4812 - 3.007 0.612 - 529.1 1 2 0 -0.0025 14 0 0 0 1.11E+07 1.26E+08 - - - 6.3232 1 221125_WJC_METTL3_EV_vs_WT_F07.17416.17416.2 1.12E-08 19/28 K.NQVAMNPTNTVFDAK[136.11].R "sp|P11142|HSP7C_HUMAN,tr|E9PQQ4|E9PQQ4_HUMAN,tr|E9PNE6|E9PNE6_HUMAN,tr|E9PKE3|E9PKE3_HUMAN,tr|E9PLF4|E9PLF4_HUMAN,tr|E9PK54|E9PK54_HUMAN,tr|E9PN25|E9PN25_HUMAN,tr|E9PPY6|E9PPY6_HUMAN,tr|E9PQK7|E9PQK7_HUMAN" 9 1656.8021 0.03 103792 17416 2 1656.79899 829.4083 Heat shock cognate 71 kDa protein OS=Homo sapiens OX=9606 GN=HSPA8 PE=1 SV=1 5.84 2910 - 726567 - - - -1.8807 - 3.5 0.697 - 1035.9 1 2 0 -0.0031 15 0 0 0 7.97E+05 2.78E+07 - - - 7.268 1 221125_WJC_METTL3_EV_vs_WT_F07.17417.17417.3 1.62E-10 20/68 K.FAASGGFLHHMAGLSSSK[136.11].L "sp|Q9BY77|PDIP3_HUMAN,tr|F6VRR5|F6VRR5_HUMAN,tr|F8WCX5|F8WCX5_HUMAN,tr|Q8WUT1|Q8WUT1_HUMAN" 4 1811.8868 0.83 103793 17417 3 1811.883169 604.9696 Polymerase delta-interacting protein 3 OS=Homo sapiens OX=9606 GN=POLDIP3 PE=1 SV=2 8.76 2910.1 - 1.33E+06 - - - -2.025 - 3.553 0.61 - 412.1 1 2 0 -0.0037 18 0 0 0 9.65E+07 1.16E+08 - - - 8.4968 1 221125_WJC_METTL3_EV_vs_WT_F07.17418.17418.3 2.48E-08 17/84 R.GSSSSEGLGAQMDHAGTVSVFK[136.11].R "sp|Q8N9M1|CS047_HUMAN,tr|A0A804HLH2|A0A804HLH2_HUMAN" 2 2159.0044 1.37 103794 17418 3 2159.000108 720.6754 Uncharacterized protein C19orf47 OS=Homo sapiens OX=9606 GN=C19orf47 PE=1 SV=1 5.32 2910.3 - 735797 - - - -2.0097 - 3.305 0.601 - 340.7 1 2 0 -0.0043 22 0 0 0 1.61E+07 1.18E+07 - - - 8.0735 1 221125_WJC_METTL3_EV_vs_WT_F07.17422.17422.3 1.38E-09 19/80 K.ETTYYDVLGVKPNATQEELKK.A sp|P31689|DNJA1_HUMAN 1 2425.2377 0.48 103796 17422 3 2425.234186 809.4198 DnaJ homolog subfamily A member 1 OS=Homo sapiens OX=9606 GN=DNAJA1 PE=1 SV=2 4.87 2910.8 - 946014 - - - -1.437 - 3.227 0.595 - 336.6 1 2 0 -0.0035 21 0 0 0 3.60E+07 7.47E+07 - - - 7.9814 0.9987 221125_WJC_METTL3_EV_vs_WT_F07.17423.17423.3 0.0081 Sep-36 R.MVNHFIAEFK[136.11].R "sp|P11142|HSP7C_HUMAN,tr|A8K7Q2|A8K7Q2_HUMAN,tr|E9PKE3|E9PKE3_HUMAN,tr|E9PN89|E9PN89_HUMAN" 4 1242.6311 0.1 103797 17423 3 1242.62996 415.2176 Heat shock cognate 71 kDa protein OS=Homo sapiens OX=9606 GN=HSPA8 PE=1 SV=1 6.5 2910.9 - 371155 - - - -0.8892 - 1.506 0.304 - 116.4 1 2 0 -0.0011 10 0 0 0 1.75E+06 1.67E+07 - - - 3.1248 1 221125_WJC_METTL3_EV_vs_WT_F07.17428.17428.4 9.67E-08 16/102 K.FAASGGFLHHMAGLSSSK.L "sp|Q9BY77|PDIP3_HUMAN,tr|F6VRR5|F6VRR5_HUMAN,tr|F8WCX5|F8WCX5_HUMAN,tr|Q8WUT1|Q8WUT1_HUMAN" 4 1803.8726 1.38 103800 17428 4 1803.869498 451.9754 Polymerase delta-interacting protein 3 OS=Homo sapiens OX=9606 GN=POLDIP3 PE=1 SV=2 8.76 2911.5 - 2.98E+06 - - - -1.7407 - 2.857 0.557 - 217.1 1 2 0 -0.0031 18 0 0 0 1.59E+08 1.15E+08 - - - 4.4329 1 221125_WJC_METTL3_EV_vs_WT_F07.17430.17430.3 2.94E-06 14/52 K.HWPFQVINDGDKPK[136.11].V "sp|P0DMV8|HS71A_HUMAN,sp|P0DMV9|HS71B_HUMAN,tr|A0A0G2JIW1|A0A0G2JIW1_HUMAN" 3 1687.8562 - 103801 17430 3 1687.856886 563.626 Heat shock 70 kDa protein 1A OS=Homo sapiens OX=9606 GN=HSPA1A PE=1 SV=1 6.75 2911.7 - 3.33E+06 - - - 0.4124 - 2.782 0.43 - 327.7 1 2 0 0.0007 14 0 0 0 - - - - - 6.053 1 221125_WJC_METTL3_EV_vs_WT_F07.17432.17432.4 7.17E-09 20/126 R.EVVAGSHELGQDYEHVTMLQER.F sp|Q01082|SPTB2_HUMAN 1 2526.1809 1.46 103803 17432 4 2526.184069 632.5525 "Spectrin beta chain, non-erythrocytic 1 OS=Homo sapiens OX=9606 GN=SPTBN1 PE=1 SV=2" 4.56 2911.9 - 1.37E+06 - - - 1.2541 - 3.318 0.607 - 258 1 2 0 0.0032 22 0 0 0 4.40E+07 3.01E+07 - - - 4.9009 0.9999 221125_WJC_METTL3_EV_vs_WT_F07.17433.17433.3 1.35E-05 16/84 R.YFENGKDVNDWVGPPNDNGVTK.E "sp|P0DTE8|AMY1C_HUMAN,sp|P0DTE7|AMY1B_HUMAN,sp|P0DUB6|AMY1A_HUMAN" 3 2464.1295 160.16 103804 17433 3 2464.128554 822.3838 Alpha-amylase 1C OS=Homo sapiens OX=9606 GN=AMY1C PE=1 SV=1 4.23 2912.1 - 1.27E+06 - - - -0.3912 - 3.007 0.562 - 193.3 1 2 1 -0.001 22 0 0 0 3.81E+07 2.38E+05 - - - 7.4156 1 221125_WJC_METTL3_EV_vs_WT_F07.17442.17442.3 5.39E-07 14/84 R.GSSSSEGLGAQMDHAGTVSVFK.R "sp|Q8N9M1|CS047_HUMAN,tr|A0A804HLH2|A0A804HLH2_HUMAN" 2 2150.9902 1.37 103811 17442 3 2150.988601 718.004 Uncharacterized protein C19orf47 OS=Homo sapiens OX=9606 GN=C19orf47 PE=1 SV=1 5.32 2913.2 - 962527 - - - -0.7652 - 3.128 0.605 - 180 1 2 0 -0.0016 22 0 0 0 1.61E+07 1.18E+07 - - - 7.9884 0.9995 221125_WJC_METTL3_EV_vs_WT_F07.17443.17443.4 3.32E-05 15/78 R.YQTLELEKEFHYNR.Y "sp|P17509|HXB6_HUMAN,sp|P09629|HXB7_HUMAN" 2 1868.9057 2.58 103812 17443 4 1868.908567 468.2337 Homeobox protein Hox-B6 OS=Homo sapiens OX=9606 GN=HOXB6 PE=1 SV=4 5.5 2913.3 - 606091 - - - 1.5271 - 2.676 0.413 - 134.3 1 2 1 0.0029 14 0 0 0 1.73E+07 6.71E+06 - - - 3.1782 0.9998 221125_WJC_METTL3_EV_vs_WT_F07.17451.17451.3 0.00239 Sep-60 K.EKPSEDMESNTFFDPR.V sp|O43395|PRPF3_HUMAN 1 1927.8258 2.69 103818 17451 3 1927.82145 643.6159 U4\U6 small nuclear ribonucleoprotein Prp3 OS=Homo sapiens OX=9606 GN=PRPF3 PE=1 SV=2 4.18 2914.3 - 654446 - - - -2.2601 - 1.852 0.482 - 46.5 1 2 0 -0.0044 16 0 0 0 5.83E+07 2.16E+07 - - - 5.4939 1 221125_WJC_METTL3_EV_vs_WT_F07.17454.17454.4 4.68E-13 25/138 K.IHVSDQELQSANASVDDSR[166.11]LEELK[136.11].A "sp|P22314|UBA1_HUMAN,tr|Q5JRR6|Q5JRR6_HUMAN" 2 2700.3321 0.69 103819 17454 4 2700.318928 676.0903 Ubiquitin-like modifier-activating enzyme 1 OS=Homo sapiens OX=9606 GN=UBA1 PE=1 SV=3 4.29 2914.7 - 538854 - - - -4.8916 - 4.287 0.683 - 254.9 1 2 1 -0.0132 24 0 0 0 6.63E+06 9.54E+06 - - - 5.6344 1 221125_WJC_METTL3_EV_vs_WT_F07.17459.17459.4 4.14E-06 13/108 R.RGKPPPLLPSVLGPAGGDR.E "sp|Q8IY67|RAVR1_HUMAN,tr|E9PAU2|E9PAU2_HUMAN,tr|A0A087WZ13|A0A087WZ13_HUMAN" 3 1883.0741 0.9 103824 17459 4 1883.071145 471.7758 Ribonucleoprotein PTB-binding 1 OS=Homo sapiens OX=9606 GN=RAVER1 PE=1 SV=1 10.84 2915.3 - 261503 - - - -1.5772 - 2.502 0.525 - 95.6 1 2 0 -0.003 19 0 0 0 1.18E+07 1.31E+07 - - - 4.105 1 221125_WJC_METTL3_EV_vs_WT_F07.17461.17461.4 7.48E-10 19/126 R.EVVAGSHELGQDYEHVTMLQER[166.11].F sp|Q01082|SPTB2_HUMAN 1 2536.1892 1.45 103825 17461 4 2536.194006 635.0546 "Spectrin beta chain, non-erythrocytic 1 OS=Homo sapiens OX=9606 GN=SPTBN1 PE=1 SV=2" 4.56 2915.6 - 1.35E+06 - - - 1.9064 - 2.987 0.605 - 189.1 1 2 0 0.0048 22 0 0 0 4.40E+07 3.03E+07 - - - 4.8486 0.9998 221125_WJC_METTL3_EV_vs_WT_F07.17463.17463.3 1.83E-06 14/68 K.YVHYEIDAC[160.03]MDSEAPGSK[136.11].D "sp|Q86U44|MTA70_HUMAN,tr|H0YFV6|H0YFV6_HUMAN" 2 2078.8805 0.07 103826 17463 3 2078.869409 693.9674 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 4.31 2915.8 - 602018 - - - -5.3312 - 3.18 0.605 - 200.9 1 2 0 -0.0111 18 0 0 0 1.20E+06 1.76E+07 - - - 8.1628 1 221125_WJC_METTL3_EV_vs_WT_F07.17465.17465.3 5.04E-14 17/88 R.FTSQQGPIKPVSPNSSPFGTDYR.N sp|Q9P2B4|CT2NL_HUMAN 1 2509.2238 8.46 103827 17465 3 2509.220861 837.4152 CTTNBP2 N-terminal-like protein OS=Homo sapiens OX=9606 GN=CTTNBP2NL PE=1 SV=2 8.59 2916.1 - 519723 - - - -1.1525 - 3.614 0.704 - 218.4 1 2 0 -0.0029 23 0 0 0 1.51E+07 1.79E+06 - - - 9.4022 1 221125_WJC_METTL3_EV_vs_WT_F07.17475.17475.3 5.85E-09 16/68 K.FAASGGFLHHMAGLSSSK.L "sp|Q9BY77|PDIP3_HUMAN,tr|F6VRR5|F6VRR5_HUMAN,tr|F8WCX5|F8WCX5_HUMAN,tr|Q8WUT1|Q8WUT1_HUMAN" 4 1803.8726 0.87 103835 17475 3 1803.874366 602.2982 Polymerase delta-interacting protein 3 OS=Homo sapiens OX=9606 GN=POLDIP3 PE=1 SV=2 8.76 2917.2 - 6.08E+06 - - - 0.9579 - 3.144 0.626 - 288.7 1 2 0 0.0017 18 0 0 0 9.65E+07 1.11E+08 - - - 8.3712 1 221125_WJC_METTL3_EV_vs_WT_F07.17486.17486.4 1.14E-08 17/108 R.R[166.11]GK[136.11]PPPLLPSVLGPAGGDR[166.11].E "sp|Q8IY67|RAVR1_HUMAN,tr|E9PAU2|E9PAU2_HUMAN,tr|A0A087WZ13|A0A087WZ13_HUMAN" 3 1911.1049 0.93 103842 17486 4 1911.10181 478.7835 Ribonucleoprotein PTB-binding 1 OS=Homo sapiens OX=9606 GN=RAVER1 PE=1 SV=1 10.84 2918.6 - 398867 - - - -1.5933 - 3.473 0.631 - 298.7 1 2 0 -0.003 19 0 0 0 1.23E+07 1.32E+07 - - - 5.1385 0.9994 221125_WJC_METTL3_EV_vs_WT_F07.17487.17487.4 1.35E-07 13/90 K.LEQMPSK[136.11]EDAIEHFMK[136.11].L "sp|P09874|PARP1_HUMAN,tr|A0A7I2V3E1|A0A7I2V3E1_HUMAN" 2 1947.9405 1.18 103843 17487 4 1947.945683 487.9924 Poly [ADP-ribose] polymerase 1 OS=Homo sapiens OX=9606 GN=PARP1 PE=1 SV=4 4.83 2918.7 - 395746 - - - 2.6505 - 2.997 0.443 - 115.2 1 2 1 0.0052 16 0 0 0 6.22E+06 5.27E+06 - - - 3.4671 1 221125_WJC_METTL3_EV_vs_WT_F07.17491.17491.3 4.97E-08 18/72 R.RGKPPPLLPSVLGPAGGDR.E "sp|Q8IY67|RAVR1_HUMAN,tr|E9PAU2|E9PAU2_HUMAN,tr|A0A087WZ13|A0A087WZ13_HUMAN" 3 1883.0741 0.79 103845 17491 3 1883.07735 628.6986 Ribonucleoprotein PTB-binding 1 OS=Homo sapiens OX=9606 GN=RAVER1 PE=1 SV=1 10.84 2919.2 - 508414 - - - 1.7179 - 2.958 0.545 - 282.2 1 2 0 0.0032 19 0 0 0 1.65E+07 2.08E+07 - - - 7.2797 0.9997 221125_WJC_METTL3_EV_vs_WT_F07.17496.17496.4 3.65E-05 13/90 R.LLIYKVSNRFSGVPDR.F sp|A0A075B6R9|KVD24_HUMAN 1 1863.0367 999 103849 17496 4 1863.03916 466.7664 Probable non-functional immunoglobulin kappa variable 2D-24 OS=Homo sapiens OX=9606 GN=IGKV2D-24 PE=1 SV=1 9.99 2919.8 - 357408 - - - 1.3381 - 2.432 0.454 - 156 1 2 2 0.0025 16 0 0 0 8.35E+06 0.00E+00 - - - 3.49 0.9999 221125_WJC_METTL3_EV_vs_WT_F07.17499.17499.4 6.31E-06 12/108 R.GLLQDDAHPTLVTYADHSK[136.11].L "sp|Q86U44|MTA70_HUMAN,tr|F5H6D8|F5H6D8_HUMAN,tr|H0YFV6|H0YFV6_HUMAN,tr|B4DTN4|B4DTN4_HUMAN" 4 2088.0367 0.02 103850 17499 4 2088.036765 523.0165 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 5.13 2920.1 - 1.04E+06 - - - 0.0153 - 2.629 0.456 - 115.9 1 2 0 0 19 0 0 0 8.79E+05 3.73E+07 - - - 3.522 0.9995 221125_WJC_METTL3_EV_vs_WT_F07.17501.17501.3 0.0007 Dec-76 K.EK[136.11]EVDGLLTSEPMGSPVSSK[136.11].T "sp|Q8WWM7|ATX2L_HUMAN,tr|H3BUF6|H3BUF6_HUMAN" 2 2105.0533 1.25 103852 17501 3 2105.051667 702.6917 Ataxin-2-like protein OS=Homo sapiens OX=9606 GN=ATXN2L PE=1 SV=2 4.41 2920.4 - 490517 - - - -0.7762 - 2.671 0.382 - 141 1 2 1 -0.0016 20 0 0 0 2.23E+07 1.79E+07 - - - 5.1819 0.9999 221125_WJC_METTL3_EV_vs_WT_F07.17502.17502.3 1.98E-06 Dec-72 K.LSQLEEHLSQLQDNPPQEK.G "sp|Q14980|NUMA1_HUMAN,tr|A0A087WY61|A0A087WY61_HUMAN,tr|F5H4J1|F5H4J1_HUMAN,tr|F5H6Y5|F5H6Y5_HUMAN" 4 2232.1022 1.51 103853 17502 3 2232.108145 745.0414 Nuclear mitotic apparatus protein 1 OS=Homo sapiens OX=9606 GN=NUMA1 PE=1 SV=2 4.4 2920.6 - 371293 - - - 2.6455 - 2.842 0.522 - 127.7 1 2 0 0.0059 19 0 0 0 1.33E+07 8.84E+06 - - - 6.9243 0.9939 221125_WJC_METTL3_EV_vs_WT_F07.17503.17503.4 0.00353 Aug-90 K.LEQMPSKEDAIEHFMK.L "sp|P09874|PARP1_HUMAN,tr|A0A7I2V3E1|A0A7I2V3E1_HUMAN" 2 1931.9121 1.16 103854 17503 4 1931.911724 483.9853 Poly [ADP-ribose] polymerase 1 OS=Homo sapiens OX=9606 GN=PARP1 PE=1 SV=4 4.83 2920.7 - 255200 - - - -0.205 - 1.903 0.32 - 27.3 3 2 1 -0.0004 16 0 0 0 6.22E+06 5.35E+06 - - - 1.8742 0.9978 221125_WJC_METTL3_EV_vs_WT_F07.17509.17509.4 0.00204 14/114 R.ILSTIDRELLKPNASVALHK.H sp|P43686|PRS6B_HUMAN 1 2217.2845 0.71 103858 17509 4 2217.289709 555.3284 26S proteasome regulatory subunit 6B OS=Homo sapiens OX=9606 GN=PSMC4 PE=1 SV=2 8.6 2921.5 - 610473 - - - 2.3484 - 2.539 0.355 - 109.9 1 2 1 0.0052 20 0 0 0 7.21E+06 1.02E+07 - - - 2.626 0.9999 221125_WJC_METTL3_EV_vs_WT_F07.17510.17510.3 1.75E-05 18/72 R.R[166.11]GK[136.11]PPPLLPSVLGPAGGDR[166.11].E "sp|Q8IY67|RAVR1_HUMAN,tr|E9PAU2|E9PAU2_HUMAN,tr|A0A087WZ13|A0A087WZ13_HUMAN" 3 1911.1049 0.84 103859 17510 3 1911.111454 638.0422 Ribonucleoprotein PTB-binding 1 OS=Homo sapiens OX=9606 GN=RAVER1 PE=1 SV=1 10.84 2921.6 - 599740 - - - 3.453 - 3.032 0.528 - 325.6 1 2 0 0.0066 19 0 0 0 1.64E+07 1.94E+07 - - - 7.15 1 221125_WJC_METTL3_EV_vs_WT_F07.17518.17518.4 4.41E-08 16/114 K.QGTLSEFVVVSGNEVSHK[136.11]PK[136.11].S "sp|Q8WWV3|RT4I1_HUMAN,tr|G3V1R2|G3V1R2_HUMAN" 2 2157.1401 1.39 103865 17518 4 2157.139814 540.2923 "Reticulon-4-interacting protein 1, mitochondrial OS=Homo sapiens OX=9606 GN=RTN4IP1 PE=1 SV=2" 6.76 2922.6 - 370610 - - - -0.1247 - 3.101 0.465 - 197.8 1 2 0 -0.0003 20 0 0 0 5.15E+06 3.72E+06 - - - 3.6516 0.9996 221125_WJC_METTL3_EV_vs_WT_F07.17519.17519.3 8.23E-08 15/76 R.LKETIDNNSVSSPLQSLQQR.T "sp|P60228|EIF3E_HUMAN,tr|A0A7I2V3I2|A0A7I2V3I2_HUMAN,tr|H0YBP5|H0YBP5_HUMAN,tr|A0A7I2V5Z6|A0A7I2V5Z6_HUMAN,tr|A0A7I2V2H9|A0A7I2V2H9_HUMAN,tr|B3KW56|B3KW56_HUMAN,tr|A0A7I2V4B4|A0A7I2V4B4_HUMAN,tr|E5RGA2|E5RGA2_HUMAN,tr|A0A7I2V3I0|A0A7I2V3I0_HUMAN,tr|A0A7I2V3S3|A0A7I2V3S3_HUMAN,tr|A0A7I2V4G3|A0A7I2V4G3_HUMAN,tr|E5RHS5|E5RHS5_HUMAN,tr|A0A7I2V2W0|A0A7I2V2W0_HUMAN,tr|A0A7I2V5P9|A0A7I2V5P9_HUMAN" 14 2256.171 1.25 103866 17519 3 2256.177651 753.0643 Eukaryotic translation initiation factor 3 subunit E OS=Homo sapiens OX=9606 GN=EIF3E PE=1 SV=1 6.07 2922.8 - 319524 - - - 2.9528 - 2.681 0.527 - 223.2 1 2 1 0.0067 20 0 0 0 2.99E+07 2.38E+07 - - - 6.8062 0.9999 221125_WJC_METTL3_EV_vs_WT_F07.17523.17523.4 1.62E-12 32/132 R.MLPQAATEDDIRGQLQSHGVQAR.E sp|P98175|RBM10_HUMAN 1 2520.2503 2.6 103868 17523 4 2520.253425 631.0699 RNA-binding protein 10 OS=Homo sapiens OX=9606 GN=RBM10 PE=1 SV=3 5.36 2923.3 - 1.99E+06 - - - 1.2328 - 4.838 0.551 - 1023.9 1 2 1 0.0031 23 0 0 0 4.78E+07 1.84E+07 - - - 4.5318 1 221125_WJC_METTL3_EV_vs_WT_F07.17524.17524.3 3.94E-09 22/84 R.QPYAVSELAGHQTSAESWGTGR.A "sp|P36578|RL4_HUMAN,tr|H3BTP7|H3BTP7_HUMAN,tr|H3BU31|H3BU31_HUMAN" 3 2331.088 1.19 103869 17524 3 2331.090612 778.0366 60S ribosomal protein L4 OS=Homo sapiens OX=9606 GN=RPL4 PE=1 SV=5 5.4 2923.4 - 589135 - - - 1.1261 - 3.846 0.521 - 463.2 1 2 0 0.0026 22 0 0 0 1.09E+07 9.14E+06 - - - 7.5415 1 221125_WJC_METTL3_EV_vs_WT_F07.17531.17531.3 2.58E-11 17/84 R.QPYAVSELAGHQTSAESWGTGR[166.11].A "sp|P36578|RL4_HUMAN,tr|H3BTP7|H3BTP7_HUMAN,tr|H3BU31|H3BU31_HUMAN" 3 2341.0963 1.19 103874 17531 3 2341.099407 781.3727 60S ribosomal protein L4 OS=Homo sapiens OX=9606 GN=RPL4 PE=1 SV=5 5.4 2924.4 - 583333 - - - 1.3455 - 3.585 0.598 - 305.2 1 2 0 0.0032 22 0 0 0 1.09E+07 9.14E+06 - - - 8.2332 0.9999 221125_WJC_METTL3_EV_vs_WT_F07.17532.17532.3 0.000238 17/76 R.LK[136.11]ETIDNNSVSSPLQSLQQR[166.11].T "sp|P60228|EIF3E_HUMAN,tr|A0A7I2V3I2|A0A7I2V3I2_HUMAN,tr|H0YBP5|H0YBP5_HUMAN,tr|A0A7I2V5Z6|A0A7I2V5Z6_HUMAN,tr|A0A7I2V2H9|A0A7I2V2H9_HUMAN,tr|B3KW56|B3KW56_HUMAN,tr|A0A7I2V4B4|A0A7I2V4B4_HUMAN,tr|E5RGA2|E5RGA2_HUMAN,tr|A0A7I2V3I0|A0A7I2V3I0_HUMAN,tr|A0A7I2V3S3|A0A7I2V3S3_HUMAN,tr|A0A7I2V4G3|A0A7I2V4G3_HUMAN,tr|E5RHS5|E5RHS5_HUMAN,tr|A0A7I2V2W0|A0A7I2V2W0_HUMAN,tr|A0A7I2V5P9|A0A7I2V5P9_HUMAN" 14 2274.1935 1.25 103875 17532 3 2274.195243 759.0718 Eukaryotic translation initiation factor 3 subunit E OS=Homo sapiens OX=9606 GN=EIF3E PE=1 SV=1 6.07 2924.5 - 550843 - - - 0.7845 - 3.37 0.451 - 352.5 1 2 1 0.0018 20 0 0 0 2.99E+07 2.38E+07 - - - 6.5151 0.9093 221125_WJC_METTL3_EV_vs_WT_F07.17533.17533.3 0.222 Sep-60 K.ILRYENEVLQLEEDER[166.11].F "sp|Q07699|SCN1B_HUMAN,tr|A0A6Q8PHF7|A0A6Q8PHF7_HUMAN,tr|A0A1W2PR05|A0A1W2PR05_HUMAN,tr|A0A6Q8PGS1|A0A6Q8PGS1_HUMAN,tr|A0A1W2PS68|A0A1W2PS68_HUMAN" 5 2057.0305 - 103876 17533 3 2057.031936 686.6841 Sodium channel subunit beta-1 OS=Homo sapiens OX=9606 GN=SCN1B PE=1 SV=1 4.14 2924.6 - 213831 - - - 0.7132 - 1.95 0.099 - 112.7 1 2 1 0.0015 16 0 0 0 - - - - - 1.3569 1 221125_WJC_METTL3_EV_vs_WT_F07.17537.17537.3 7.17E-17 21/88 K.K[136.11]AAAPAPEEEMDEC[160.03]EQALAAEPK[136.11].A sp|P26641|EF1G_HUMAN 1 2500.1433 1.06 103878 17537 3 2500.14632 834.3884 Elongation factor 1-gamma OS=Homo sapiens OX=9606 GN=EEF1G PE=1 SV=3 4.06 2925.1 - 1.08E+06 - - - 1.2255 - 4.203 0.795 - 372.3 1 2 0 0.0031 23 0 0 0 9.92E+07 9.38E+07 - - - 10.7709 0.9994 221125_WJC_METTL3_EV_vs_WT_F07.17538.17538.4 6.30E-05 17/96 R.EDLR[166.11]LPEGDLGK[136.11]EIEQK[136.11].Y "sp|P63241|IF5A1_HUMAN,sp|Q6IS14|IF5AL_HUMAN,tr|I3L397|I3L397_HUMAN,tr|I3L504|I3L504_HUMAN" 4 1994.0531 1.01 103879 17538 4 1994.058052 499.5205 Eukaryotic translation initiation factor 5A-1 OS=Homo sapiens OX=9606 GN=EIF5A PE=1 SV=2 4.36 2925.1 - 1.07E+06 - - - 2.506 - 2.403 0.449 - 130.7 1 2 2 0.005 17 0 0 0 2.84E+07 2.81E+07 - - - 3.4371 0.9998 221125_WJC_METTL3_EV_vs_WT_F07.17540.17540.3 1.11E-05 18/48 R.K[136.11]R[166.11]EELSNVLAAMR[166.11].K sp|Q9Y3U8|RL36_HUMAN 1 1543.8499 0.91 103881 17540 3 1543.852606 515.6239 60S ribosomal protein L36 OS=Homo sapiens OX=9606 GN=RPL36 PE=1 SV=3 8.75 2925.4 - 441912 - - - 1.7618 - 2.755 0.482 - 529.9 1 2 1 0.0027 13 0 0 0 1.95E+07 2.14E+07 - - - 6.6607 0.9993 221125_WJC_METTL3_EV_vs_WT_F07.17542.17542.4 0.00477 Oct-96 R.GAPPSSNIEDFHGLLPK[136.11].G "sp|P43243|MATR3_HUMAN,tr|A8MXP9|A8MXP9_HUMAN,tr|D6R991|D6R991_HUMAN,tr|A0A0R4J2E8|A0A0R4J2E8_HUMAN,tr|H0Y8T4|H0Y8T4_HUMAN,tr|D6REM6|D6REM6_HUMAN" 6 1785.9141 1.22 103883 17542 4 1785.917509 447.4858 Matrin-3 OS=Homo sapiens OX=9606 GN=MATR3 PE=1 SV=2 5.32 2925.6 - 289519 - - - 1.9094 - 1.561 0.344 - 49.8 1 2 0 0.0034 17 0 0 0 5.95E+06 4.87E+06 - - - 2.3738 0.9967 221125_WJC_METTL3_EV_vs_WT_F07.17545.17545.4 0.000134 16/96 R.EDLRLPEGDLGKEIEQK.Y "sp|P63241|IF5A1_HUMAN,sp|Q6IS14|IF5AL_HUMAN,tr|I3L397|I3L397_HUMAN,tr|I3L504|I3L504_HUMAN" 4 1968.0164 1.01 103884 17545 4 1968.020242 493.0114 Eukaryotic translation initiation factor 5A-1 OS=Homo sapiens OX=9606 GN=EIF5A PE=1 SV=2 4.36 2926.1 - 1.64E+06 - - - 1.9598 - 2.431 0.32 - 97.8 1 2 2 0.0039 17 0 0 0 2.84E+07 2.82E+07 - - - 2.3186 1 221125_WJC_METTL3_EV_vs_WT_F07.17546.17546.3 4.80E-08 24/64 R.EDLR[166.11]LPEGDLGK[136.11]EIEQK[136.11].Y "sp|P63241|IF5A1_HUMAN,sp|Q6IS14|IF5AL_HUMAN,tr|I3L397|I3L397_HUMAN,tr|I3L504|I3L504_HUMAN" 4 1994.0531 1.11 103885 17546 3 1994.058349 665.6916 Eukaryotic translation initiation factor 5A-1 OS=Homo sapiens OX=9606 GN=EIF5A PE=1 SV=2 4.36 2926.2 - 652804 - - - 2.6549 - 4.289 0.575 - 956.5 1 2 2 0.0053 17 0 0 0 1.60E+07 1.44E+07 - - - 8.6276 0.9876 221125_WJC_METTL3_EV_vs_WT_F07.17547.17547.3 0.000953 Dec-76 F.QSSELVSWADGGQHSSIHPA.- "sp|O00746|NDKM_HUMAN,tr|Q4TT34|Q4TT34_HUMAN,tr|A0A087WVT9|A0A087WVT9_HUMAN" 3 2091.961 - 103886 17547 3 2091.965192 698.3276 "Nucleoside diphosphate kinase, mitochondrial OS=Homo sapiens OX=9606 GN=NME4 PE=1 SV=1" 5.15 2926.3 - 551433 - - - 2.0058 - 2.93 0.407 - 97.2 1 1 0 0.0042 20 0 0 0 - - - - - 5.6845 0.9991 221125_WJC_METTL3_EV_vs_WT_F07.17554.17554.4 5.83E-06 23/102 K.EGQEEVLKEVVESEGERK.T "sp|Q8TAQ2|SMRC2_HUMAN,tr|F8VXC8|F8VXC8_HUMAN" 2 2073.0226 3.15 103891 17554 4 2073.030311 519.2629 SWI\SNF complex subunit SMARCC2 OS=Homo sapiens OX=9606 GN=SMARCC2 PE=1 SV=1 4.36 2927.3 - 759024 - - - 3.7231 - 3.5 0.476 - 375.8 1 2 1 0.0077 18 0 0 0 1.63E+07 5.17E+06 - - - 3.7961 0.9973 221125_WJC_METTL3_EV_vs_WT_F07.17555.17555.4 0.045 Nov-96 R.GAPPSSNIEDFHGLLPK.G "sp|P43243|MATR3_HUMAN,tr|A8MXP9|A8MXP9_HUMAN,tr|D6R991|D6R991_HUMAN,tr|A0A0R4J2E8|A0A0R4J2E8_HUMAN,tr|H0Y8T4|H0Y8T4_HUMAN,tr|D6REM6|D6REM6_HUMAN" 6 1777.8999 1.22 103892 17555 4 1777.903918 445.4823 Matrin-3 OS=Homo sapiens OX=9606 GN=MATR3 PE=1 SV=2 5.32 2927.4 - 338986 - - - 2.2605 - 1.48 0.292 - 35.9 1 2 0 0.004 17 0 0 0 5.95E+06 4.87E+06 - - - 1.9026 0.9995 221125_WJC_METTL3_EV_vs_WT_F07.17557.17557.3 5.39E-06 15/88 R.MLPQAATEDDIRGQLQSHGVQAR.E sp|P98175|RBM10_HUMAN 1 2520.2503 3.27 103894 17557 3 2520.257923 841.0907 RNA-binding protein 10 OS=Homo sapiens OX=9606 GN=RBM10 PE=1 SV=3 5.36 2927.6 - 437328 - - - 3.0176 - 2.578 0.522 - 208.7 1 2 1 0.0076 23 0 0 0 5.72E+06 1.75E+06 - - - 6.5793 1 221125_WJC_METTL3_EV_vs_WT_F07.17558.17558.3 2.74E-12 21/92 R.APVAPAFGGGSSVAGFGSPGSHSH.T "sp|O15504|NUP42_HUMAN,tr|C9JYA1|C9JYA1_HUMAN" 2 2136.9977 - 103895 17558 3 2136.991924 713.3398 Nucleoporin NUP42 OS=Homo sapiens OX=9606 GN=NUP42 PE=1 SV=1 6.96 2927.7 - 387058 - - - -2.7103 - 4.18 0.674 - 453.3 1 1 0 -0.0058 24 0 0 0 - - - - - 9.3749 0.9995 221125_WJC_METTL3_EV_vs_WT_F07.17559.17559.3 5.38E-08 20/68 K.EGQEEVLKEVVESEGERK.T "sp|Q8TAQ2|SMRC2_HUMAN,tr|F8VXC8|F8VXC8_HUMAN" 2 2073.0226 13.89 103896 17559 3 2073.03141 692.0148 SWI\SNF complex subunit SMARCC2 OS=Homo sapiens OX=9606 GN=SMARCC2 PE=1 SV=1 4.36 2927.9 - 364773 - - - 4.2532 - 3.667 0.559 - 496.9 1 2 1 0.0088 18 0 0 0 1.51E+07 1.08E+06 - - - 8.0054 0.9996 221125_WJC_METTL3_EV_vs_WT_F07.17560.17560.3 0.000388 18/84 R.SAGQGEVLVYVEDPAGHQEEAK[136.11].V "sp|P21333|FLNA_HUMAN,tr|A0A7P0NMY4|A0A7P0NMY4_HUMAN,tr|Q60FE5|Q60FE5_HUMAN,tr|A0A7I2V3E6|A0A7I2V3E6_HUMAN,tr|A0A087WWY3|A0A087WWY3_HUMAN,tr|F8WE98|F8WE98_HUMAN" 6 2320.1063 1.17 103897 17560 3 2320.118067 774.376 Filamin-A OS=Homo sapiens OX=9606 GN=FLNA PE=1 SV=4 4.25 2928 - 346039 - - - 5.0847 - 3.486 0.486 - 272.5 1 2 0 0.0118 22 0 0 0 4.04E+07 3.44E+07 - - - 6.9157 1 221125_WJC_METTL3_EV_vs_WT_F07.17561.17561.3 1.05E-13 23/84 R.SAGQGEVLVYVEDPAGHQEEAK.V "sp|P21333|FLNA_HUMAN,tr|A0A7P0NMY4|A0A7P0NMY4_HUMAN,tr|Q60FE5|Q60FE5_HUMAN,tr|A0A7I2V3E6|A0A7I2V3E6_HUMAN,tr|A0A087WWY3|A0A087WWY3_HUMAN,tr|F8WE98|F8WE98_HUMAN" 6 2312.0921 1.18 103898 17561 3 2312.09543 771.7046 Filamin-A OS=Homo sapiens OX=9606 GN=FLNA PE=1 SV=4 4.25 2928.1 - 306905 - - - 1.4532 - 4.141 0.613 - 563 1 2 0 0.0034 22 0 0 0 4.05E+07 3.44E+07 - - - 8.7422 0.9987 221125_WJC_METTL3_EV_vs_WT_F07.17562.17562.4 0.00014 13/72 R.K[136.11]R[166.11]EELSNVLAAMR[166.11].K sp|Q9Y3U8|RL36_HUMAN 1 1543.8499 0.01 103899 17562 4 1543.851673 386.9697 60S ribosomal protein L36 OS=Homo sapiens OX=9606 GN=RPL36 PE=1 SV=3 8.75 2928.3 - 245661 - - - 1.1575 - 2.129 0.35 - 151.9 1 2 1 0.0018 13 0 0 0 4.17E+04 5.02E+06 - - - 2.5521 0.9996 221125_WJC_METTL3_EV_vs_WT_F07.17569.17569.3 4.02E-08 24/64 R.EDLRLPEGDLGKEIEQK.Y "sp|P63241|IF5A1_HUMAN,sp|Q6IS14|IF5AL_HUMAN,tr|I3L397|I3L397_HUMAN,tr|I3L504|I3L504_HUMAN" 4 1968.0164 1.11 103904 17569 3 1968.024186 657.0127 Eukaryotic translation initiation factor 5A-1 OS=Homo sapiens OX=9606 GN=EIF5A PE=1 SV=2 4.36 2929.1 - 1.46E+06 - - - 3.9639 - 3.748 0.547 - 825 1 2 2 0.0078 17 0 0 0 1.60E+07 1.44E+07 - - - 7.9742 0.9999 221125_WJC_METTL3_EV_vs_WT_F07.17572.17572.3 0.00267 21/64 K.NR[166.11]PSSGSLIQVVTTEGR[166.11].T sp|P09417|DHPR_HUMAN 1 1819.9655 0.3 103907 17572 3 1819.97109 607.6624 Dihydropteridine reductase OS=Homo sapiens OX=9606 GN=QDPR PE=1 SV=2 9.6 2929.5 - 641339 - - - 3.0632 - 3.641 0.431 - 703.8 1 2 0 0.0056 17 0 0 0 3.06E+06 1.02E+07 - - - 6.6083 0.9974 221125_WJC_METTL3_EV_vs_WT_F07.17573.17573.4 0.00599 19/102 K.EGQEEVLK[136.11]EVVESEGER[166.11]K[136.11].T "sp|Q8TAQ2|SMRC2_HUMAN,tr|F8VXC8|F8VXC8_HUMAN" 2 2099.0593 3.2 103908 17573 4 2099.066143 525.7721 SWI\SNF complex subunit SMARCC2 OS=Homo sapiens OX=9606 GN=SMARCC2 PE=1 SV=1 4.36 2929.6 - 553620 - - - 3.2777 - 2.971 0.378 - 271.4 1 2 1 0.0069 18 0 0 0 1.62E+07 5.05E+06 - - - 2.8872 0.9999 221125_WJC_METTL3_EV_vs_WT_F07.17576.17576.4 1.52E-06 19/108 K.ETLQAVPK[136.11]PGAFDLEQVK[136.11]R[166.11].S sp|O00411|RPOM_HUMAN 1 2151.1898 1.29 103911 17576 4 2151.194653 538.8047 "DNA-directed RNA polymerase, mitochondrial OS=Homo sapiens OX=9606 GN=POLRMT PE=1 SV=2" 6.28 2930 - 238768 - - - 2.2448 - 3.439 0.483 - 225.5 1 2 0 0.0048 19 0 0 0 5.40E+06 4.20E+06 - - - 3.8465 0.9814 221125_WJC_METTL3_EV_vs_WT_F07.17580.17580.3 0.0401 Aug-40 K.GKPLALVEEIR.N "sp|Q9BSD7|NTPCR_HUMAN,tr|Q5TDF0|Q5TDF0_HUMAN" 2 1223.7238 1.26 103915 17580 3 1223.728248 408.9152 Cancer-related nucleoside-triphosphatase OS=Homo sapiens OX=9606 GN=NTPCR PE=1 SV=1 6.14 2930.5 - 91948.7 - - - 3.6577 - 1.64 0.234 - 100.5 1 2 0 0.0045 11 0 0 0 1.79E+06 1.43E+06 - - - 2.553 1 221125_WJC_METTL3_EV_vs_WT_F07.17582.17582.3 3.75E-09 22/76 R.QQVAFYGQTLGQAQAHSQEQ.- sp|Q96I24|FUBP3_HUMAN 1 2218.0403 - 103916 17582 3 2218.04683 740.354 Far upstream element-binding protein 3 OS=Homo sapiens OX=9606 GN=FUBP3 PE=1 SV=2 5.24 2930.8 - 2.25E+06 - - - 2.94 - 3.569 0.565 - 482.5 1 2 0 0.0065 20 0 0 0 - - - - - 7.924 0.9996 221125_WJC_METTL3_EV_vs_WT_F07.17586.17586.4 5.30E-09 23/108 K.ETLQAVPKPGAFDLEQVKR.S sp|O00411|RPOM_HUMAN 1 2125.1532 1.29 103919 17586 4 2125.165022 532.2956 "DNA-directed RNA polymerase, mitochondrial OS=Homo sapiens OX=9606 GN=POLRMT PE=1 SV=2" 6.28 2931.3 - 325670 - - - 5.5845 - 3.542 0.567 - 398.1 1 2 0 0.0119 19 0 0 0 5.40E+06 4.20E+06 - - - 4.5857 0.9869 221125_WJC_METTL3_EV_vs_WT_F07.17590.17590.3 0.0117 Jul-72 K.LK[136.11]EALNSLSQLSYSTSSSK[136.11].R sp|Q9P0K7|RAI14_HUMAN 1 2058.0816 4 103923 17590 3 2058.087323 687.0345 Ankycorbin OS=Homo sapiens OX=9606 GN=RAI14 PE=1 SV=2 8.5 2931.8 - 172315 - - - 2.7978 - 1.718 0.318 - 55.8 1 2 1 0.0058 19 0 0 0 2.63E+06 6.57E+05 - - - 3.4133 1 221125_WJC_METTL3_EV_vs_WT_F07.17593.17593.3 7.23E-06 20/52 K.HWPFQVINDGDK[136.11]PK[136.11].V "sp|P0DMV8|HS71A_HUMAN,sp|P0DMV9|HS71B_HUMAN,tr|A0A0G2JIW1|A0A0G2JIW1_HUMAN" 3 1695.8704 0.14 103925 17593 3 1695.876921 566.2974 Heat shock 70 kDa protein 1A OS=Homo sapiens OX=9606 GN=HSPA1A PE=1 SV=1 6.75 2932.2 - 9.61E+06 - - - 3.8511 - 3.234 0.623 - 776.5 1 2 0 0.0065 14 0 0 0 1.06E+09 7.75E+09 - - - 8.6032 1 221125_WJC_METTL3_EV_vs_WT_F07.17594.17594.4 4.66E-06 20/78 K.HWPFQVINDGDK[136.11]PK[136.11].V "sp|P0DMV8|HS71A_HUMAN,sp|P0DMV9|HS71B_HUMAN,tr|A0A0G2JIW1|A0A0G2JIW1_HUMAN" 3 1695.8704 0.14 103926 17594 4 1695.875138 424.9749 Heat shock 70 kDa protein 1A OS=Homo sapiens OX=9606 GN=HSPA1A PE=1 SV=1 6.75 2932.2 - 2.70E+06 - - - 2.7997 - 3.338 0.624 - 308.5 1 2 0 0.0047 14 0 0 0 2.61E+08 1.81E+09 - - - 5.0947 0.9996 221125_WJC_METTL3_EV_vs_WT_F07.17595.17595.3 1.55E-08 16/48 R.KREELSNVLAAMR.K sp|Q9Y3U8|RL36_HUMAN 1 1515.8191 0.9 103927 17595 3 1515.824434 506.2803 60S ribosomal protein L36 OS=Homo sapiens OX=9606 GN=RPL36 PE=1 SV=3 8.75 2932.3 - 1.41E+06 - - - 3.4885 - 2.72 0.561 - 393.2 1 2 1 0.0053 13 0 0 0 1.93E+07 2.14E+07 - - - 7.5061 0.9989 221125_WJC_METTL3_EV_vs_WT_F07.17596.17596.4 0.0472 14/96 K.QVK[136.11]PYVEEGLHPQIIIR[166.11].A "sp|Q99832|TCPH_HUMAN,tr|F8WAM2|F8WAM2_HUMAN" 2 2036.1538 0.15 103928 17596 4 2036.161653 510.0457 T-complex protein 1 subunit eta OS=Homo sapiens OX=9606 GN=CCT7 PE=1 SV=2 6.76 2932.4 - 889598 - - - 3.8735 - 2.91 0.376 - 111.9 1 2 0 0.0079 17 0 0 0 3.62E+06 2.38E+07 - - - 2.8674 0.9838 221125_WJC_METTL3_EV_vs_WT_F07.17598.17598.4 0.00955 10/114 R.AISHEHSPSDLEAHFVPLVK[136.11].R "sp|P30153|2AAA_HUMAN,tr|C9J9C1|C9J9C1_HUMAN" 2 2220.1419 0.97 103930 17598 4 2220.153597 556.0427 Serine\threonine-protein phosphatase 2A 65 kDa regulatory subunit A alpha isoform OS=Homo sapiens OX=9606 GN=PPP2R1A PE=1 SV=4 5.75 2932.7 - 311124 - - - 5.2834 - 1.923 0.3 - 46.5 1 2 0 0.0117 20 0 0 0 2.97E+07 3.07E+07 - - - 2.0526 0.899 221125_WJC_METTL3_EV_vs_WT_F07.17600.17600.3 0.178 Aug-64 R.TFNTSTGGLLLPSDTKR.S "sp|P12956|XRCC6_HUMAN,tr|B1AHC9|B1AHC9_HUMAN" 2 1806.9476 0.25 103932 17600 3 1806.956155 603.3231 X-ray repair cross-complementing protein 6 OS=Homo sapiens OX=9606 GN=XRCC6 PE=1 SV=2 8.41 2932.9 - 249070 - - - 4.7467 - 1.737 0.18 - 54.9 1 2 0 0.0086 17 0 0 0 2.93E+06 1.19E+07 - - - 1.9394 0.9998 221125_WJC_METTL3_EV_vs_WT_F07.17601.17601.3 8.90E-08 15/64 K.QVK[136.11]PYVEEGLHPQIIIR[166.11].A "sp|Q99832|TCPH_HUMAN,tr|F8WAM2|F8WAM2_HUMAN" 2 2036.1538 0.08 103933 17601 3 2036.163391 679.7252 T-complex protein 1 subunit eta OS=Homo sapiens OX=9606 GN=CCT7 PE=1 SV=2 6.76 2933.1 - 203083 - - - 4.727 - 2.851 0.543 - 219.1 1 2 0 0.0096 17 0 0 0 4.47E+05 5.79E+06 - - - 7.238 0.9997 221125_WJC_METTL3_EV_vs_WT_F07.17604.17604.3 0.000178 Aug-32 K.FYVHNDIFR.Y "sp|Q13283|G3BP1_HUMAN,tr|A0A7I2V5M7|A0A7I2V5M7_HUMAN,tr|A0A7P0P2U7|A0A7P0P2U7_HUMAN,tr|A0A7I2YQU8|A0A7I2YQU8_HUMAN,tr|A0A7I2V651|A0A7I2V651_HUMAN,tr|A0A7I2YQN9|A0A7I2YQN9_HUMAN,tr|A0A7I2V2V1|A0A7I2V2V1_HUMAN" 7 1209.5931 1.21 103936 17604 3 1209.5956 404.205 Ras GTPase-activating protein-binding protein 1 OS=Homo sapiens OX=9606 GN=G3BP1 PE=1 SV=1 6.74 2933.4 - 69184.3 - - - 2.0726 - 1.508 0.453 - 90 1 2 0 0.0025 9 0 0 0 1.99E+06 1.65E+06 - - - 4.8278 1 221125_WJC_METTL3_EV_vs_WT_F07.17609.17609.4 2.03E-11 26/144 K.VINAAHSFYNGTTTLPISDEDR[166.11]TPR[166.11].K sp|P49915|GUAA_HUMAN 1 2794.3789 1.02 103939 17609 4 2794.38791 699.602 GMP synthase [glutamine-hydrolyzing] OS=Homo sapiens OX=9606 GN=GMPS PE=1 SV=1 5.38 2934.1 - 660641 - - - 3.2204 - 4.759 0.652 - 331.4 1 2 1 0.009 25 0 0 0 2.12E+07 2.08E+07 - - - 5.3948 0.9916 221125_WJC_METTL3_EV_vs_WT_F07.17610.17610.3 0.00734 Jul-32 K.FYVHNDIFR[166.11].Y "sp|Q13283|G3BP1_HUMAN,tr|A0A7I2V5M7|A0A7I2V5M7_HUMAN,tr|A0A7P0P2U7|A0A7P0P2U7_HUMAN,tr|A0A7I2YQU8|A0A7I2YQU8_HUMAN,tr|A0A7I2V651|A0A7I2V651_HUMAN,tr|A0A7I2YQN9|A0A7I2YQN9_HUMAN,tr|A0A7I2V2V1|A0A7I2V2V1_HUMAN" 7 1219.6014 1.21 103940 17610 3 1219.605077 407.5411 Ras GTPase-activating protein-binding protein 1 OS=Homo sapiens OX=9606 GN=G3BP1 PE=1 SV=1 6.74 2934.3 - 197842 - - - 3.0453 - 1.394 0.291 - 67.7 1 2 0 0.0037 9 0 0 0 1.99E+06 1.65E+06 - - - 2.7844 1 221125_WJC_METTL3_EV_vs_WT_F07.17611.17611.2 2.40E-08 Sep-38 R.QQVAFYGQTLGQAQAHSQEQ.- sp|Q96I24|FUBP3_HUMAN 1 2218.0403 - 103941 17611 2 2218.054128 1110.0274 Far upstream element-binding protein 3 OS=Homo sapiens OX=9606 GN=FUBP3 PE=1 SV=2 5.24 2934.4 - 165128 - - - 6.2303 - 2.206 0.66 - 157.3 1 2 0 0.0138 20 0 0 0 - - - - - 5.8566 1 221125_WJC_METTL3_EV_vs_WT_F07.17612.17612.3 1.66E-08 13/80 R.FEGDASHETQEPESFSAWSDR.L "sp|Q9UBC1|IKBL1_HUMAN,tr|Q5STV6|Q5STV6_HUMAN" 2 2410.9938 1.84 103942 17612 3 2410.989289 804.6719 NF-kappa-B inhibitor-like protein 1 OS=Homo sapiens OX=9606 GN=NFKBIL1 PE=1 SV=1 4.08 2934.5 - 139974 - - - -1.876 - 2.69 0.718 - 180.2 1 2 0 -0.0045 21 0 0 0 5.56E+06 3.01E+06 - - - 8.9161 1 221125_WJC_METTL3_EV_vs_WT_F07.17618.17618.3 6.45E-09 26/84 K.SGTTSESGALSLEPSHIGDLQK.A sp|Q7Z417|NUFP2_HUMAN 1 2213.0812 3.4 103946 17618 3 2213.08795 738.701 Nuclear fragile X mental retardation-interacting protein 2 OS=Homo sapiens OX=9606 GN=NUFIP2 PE=1 SV=1 4.65 2935.4 - 2.85E+06 - - - 3.0632 - 4.096 0.591 - 623.8 1 2 0 0.0068 22 0 0 0 4.76E+07 1.40E+07 - - - 8.4701 1 221125_WJC_METTL3_EV_vs_WT_F07.17620.17620.4 1.18E-08 39/144 K.VINAAHSFYNGTTTLPISDEDRTPR.K sp|P49915|GUAA_HUMAN 1 2774.3624 1.04 103948 17620 4 2774.372967 694.5979 GMP synthase [glutamine-hydrolyzing] OS=Homo sapiens OX=9606 GN=GMPS PE=1 SV=1 5.38 2935.6 - 1.91E+06 - - - 3.8193 - 6.015 0.637 - 814.8 1 2 1 0.0106 25 0 0 0 2.17E+07 2.09E+07 - - - 5.3383 1 221125_WJC_METTL3_EV_vs_WT_F07.17621.17621.4 6.06E-09 24/114 K.K[136.11]VQGGALEDSQLVAGVAFK[136.11]K[136.11].T sp|Q99832|TCPH_HUMAN 1 2068.1743 0.13 103949 17621 4 2068.179542 518.0508 T-complex protein 1 subunit eta OS=Homo sapiens OX=9606 GN=CCT7 PE=1 SV=2 8.5 2935.7 - 1.08E+06 - - - 2.5394 - 3.328 0.597 - 445 1 2 0 0.0053 20 0 0 0 2.23E+06 1.72E+07 - - - 4.8228 0.9996 221125_WJC_METTL3_EV_vs_WT_F07.17622.17622.3 4.99E-05 14/76 K.FLGSDEEDKDSLQELSTEQK.C "sp|Q99567|NUP88_HUMAN,tr|J3KMX1|J3KMX1_HUMAN" 2 2297.0547 0.52 103950 17622 3 2297.061112 766.6922 Nuclear pore complex protein Nup88 OS=Homo sapiens OX=9606 GN=NUP88 PE=1 SV=2 3.95 2935.8 - 693766 - - - 2.7997 - 2.944 0.512 - 125.5 1 2 1 0.0064 20 0 0 0 4.87E+06 9.38E+06 - - - 6.8661 0.9654 221125_WJC_METTL3_EV_vs_WT_F07.17623.17623.4 1.66E-05 22/120 K.R[166.11]GLLQDDAHPTLVTYADHSK[136.11]L.S "sp|Q86U44|MTA70_HUMAN,tr|F5H6D8|F5H6D8_HUMAN,tr|H0YFV6|H0YFV6_HUMAN,tr|B4DTN4|B4DTN4_HUMAN" 4 2367.2302 0.03 103951 17623 4 2367.237908 592.8148 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 5.99 2935.9 - 508500 - - - 3.265 - 2.619 0.436 - 260.1 1 1 0 0.0077 21 0 0 0 2.26E+05 7.23E+06 - - - 3.3371 1 221125_WJC_METTL3_EV_vs_WT_F07.17626.17626.3 1.66E-10 17/112 R.YVAQAGLEPLASGDPSASASHAAGITGSR[166.11].H "sp|O94966|UBP19_HUMAN,tr|A0A590UK03|A0A590UK03_HUMAN,tr|A0A0A0MR08|A0A0A0MR08_HUMAN" 3 2750.3499 0.08 103954 17626 3 2750.3546 917.7906 Ubiquitin carboxyl-terminal hydrolase 19 OS=Homo sapiens OX=9606 GN=USP19 PE=1 SV=2 5.32 2936.3 - 179242 - - - 1.7067 - 3.229 0.614 - 141.1 1 2 0 0.0047 29 0 0 0 1.49E+05 1.92E+06 - - - 8.0809 1 221125_WJC_METTL3_EV_vs_WT_F07.17630.17630.3 4.76E-06 24/76 K.K[136.11]VQGGALEDSQLVAGVAFK[136.11]K[136.11].T sp|Q99832|TCPH_HUMAN 1 2068.1743 0.04 103956 17630 3 2068.179857 690.3987 T-complex protein 1 subunit eta OS=Homo sapiens OX=9606 GN=CCT7 PE=1 SV=2 8.5 2936.9 - 819984 - - - 2.6917 - 4.289 0.625 - 820.2 1 2 0 0.0056 20 0 0 0 2.80E+05 6.48E+06 - - - 9.039 0.9998 221125_WJC_METTL3_EV_vs_WT_F07.17631.17631.4 7.32E-08 19/156 K.VPPAPVNKDDFALVQRPGPGLSQEAAR.R "sp|Q6P1N0|C2D1A_HUMAN,tr|A0A7P0Z4M5|A0A7P0Z4M5_HUMAN,tr|K7EMP1|K7EMP1_HUMAN" 3 2828.4933 0.74 103957 17631 4 2828.500335 708.1306 Coiled-coil and C2 domain-containing protein 1A OS=Homo sapiens OX=9606 GN=CC2D1A PE=1 SV=1 6.09 2937 - 425122 - - - 2.478 - 3.28 0.558 - 204.1 1 2 1 0.007 27 0 0 0 2.97E+06 4.02E+06 - - - 4.4526 1 221125_WJC_METTL3_EV_vs_WT_F07.17633.17633.3 5.77E-11 23/96 K.VINAAHSFYNGTTTLPISDEDRTPR.K sp|P49915|GUAA_HUMAN 1 2774.3624 2.05 103959 17633 3 2774.368297 925.7947 GMP synthase [glutamine-hydrolyzing] OS=Homo sapiens OX=9606 GN=GMPS PE=1 SV=1 5.38 2937.3 - 400255 - - - 2.136 - 4.238 0.657 - 545.6 1 2 1 0.0059 25 0 0 0 4.38E+06 2.14E+06 - - - 9.1856 0.9987 221125_WJC_METTL3_EV_vs_WT_F07.17635.17635.3 3.42E-05 17/96 Y.SSVLTQNSLGNNHSFSTANGLSVDR.L sp|P55316|FOXG1_HUMAN 1 2604.2528 0.94 103961 17635 3 2604.256265 869.0916 Forkhead box protein G1 OS=Homo sapiens OX=9606 GN=FOXG1 PE=1 SV=2 6.46 2937.5 - 295028 - - - 1.3225 - 3.955 0.606 - 226.9 1 1 0 0.0034 25 0 0 0 2.35E+06 2.50E+06 - - - 8.4587 0.9983 221125_WJC_METTL3_EV_vs_WT_F07.17637.17637.4 0.000453 15/84 R.IDQVNQLLELDHQKR.G "sp|P61201|CSN2_HUMAN,tr|B4DIH5|B4DIH5_HUMAN" 2 1847.9854 1.87 103963 17637 4 1847.99335 463.0036 COP9 signalosome complex subunit 2 OS=Homo sapiens OX=9606 GN=COPS2 PE=1 SV=1 5.38 2937.8 - 167499 - - - 4.3236 - 2.438 0.374 - 187.8 1 2 0 0.008 15 0 0 0 4.45E+06 2.38E+06 - - - 2.798 0.9998 221125_WJC_METTL3_EV_vs_WT_F07.17645.17645.3 5.70E-09 17/88 K.VKGTAGLSQNSTLEVQTLSVAPK.A "sp|Q96QA5|GSDMA_HUMAN,tr|J3KRG2|J3KRG2_HUMAN" 2 2327.2696 999 103969 17645 3 2327.276106 776.7638 Gasdermin-A OS=Homo sapiens OX=9606 GN=GSDMA PE=1 SV=4 8.56 2938.8 - 438311 - - - 2.7784 - 3.042 0.599 - 342.1 1 2 1 0.0065 23 0 0 0 3.45E+06 0.00E+00 - - - 7.8264 0.9987 221125_WJC_METTL3_EV_vs_WT_F07.17646.17646.3 0.00352 19/64 K.EVVHTVSLHEIDVINSR[166.11].T "sp|Q9Y230|RUVB2_HUMAN,tr|M0R0Y3|M0R0Y3_HUMAN" 2 1956.0304 0.86 103970 17646 3 1956.043332 653.0174 RuvB-like 2 OS=Homo sapiens OX=9606 GN=RUVBL2 PE=1 SV=3 5.28 2938.9 - 413440 - - - 6.6062 - 3.215 0.456 - 549.6 1 2 0 0.0129 17 0 0 0 2.96E+06 3.43E+06 - - - 6.5707 1 221125_WJC_METTL3_EV_vs_WT_F07.17649.17649.3 1.25E-09 16/96 Q.GSSLASYGNQPSSYGAQAASSYGVR[166.11].A sp|Q96PK6|RBM14_HUMAN 1 2474.1338 2.36 103973 17649 3 2474.135905 825.7185 RNA-binding protein 14 OS=Homo sapiens OX=9606 GN=RBM14 PE=1 SV=2 8.5 2939.3 - 360040 - - - 0.8649 - 3.183 0.654 - 179.5 1 1 0 0.0021 25 0 0 0 7.31E+06 3.10E+06 - - - 8.4946 1 221125_WJC_METTL3_EV_vs_WT_F07.17652.17652.4 1.60E-06 14/84 R.IDQVNQLLELDHQK[136.11]R[166.11].G "sp|P61201|CSN2_HUMAN,tr|B4DIH5|B4DIH5_HUMAN" 2 1866.0078 2.01 103976 17652 4 1866.010173 467.5092 COP9 signalosome complex subunit 2 OS=Homo sapiens OX=9606 GN=COPS2 PE=1 SV=1 5.38 2939.7 - 268899 - - - 1.2556 - 2.939 0.472 - 241.3 1 2 0 0.0023 15 0 0 0 4.79E+06 2.38E+06 - - - 3.7194 0.9998 221125_WJC_METTL3_EV_vs_WT_F07.17654.17654.4 0.000124 Sep-78 K.HWPFQVINDGDKPK.V "sp|P0DMV8|HS71A_HUMAN,sp|P0DMV9|HS71B_HUMAN,tr|A0A0G2JIW1|A0A0G2JIW1_HUMAN" 3 1679.842 0.14 103978 17654 4 1679.847813 420.9678 Heat shock 70 kDa protein 1A OS=Homo sapiens OX=9606 GN=HSPA1A PE=1 SV=1 6.75 2940 - 165921 - - - 3.4664 - 1.848 0.473 - 51.3 1 2 0 0.0058 14 0 0 0 2.18E+08 1.52E+09 - - - 3.5649 0.9989 221125_WJC_METTL3_EV_vs_WT_F07.17655.17655.3 0.00177 Oct-72 K.EPSGPSELIPSSTFSAHNR[166.11].R sp|Q96GA3|LTV1_HUMAN 1 2021.9682 1.94 103979 17655 3 2021.967696 674.9967 Protein LTV1 homolog OS=Homo sapiens OX=9606 GN=LTV1 PE=1 SV=1 5.4 2940.1 - 150703 - - - -0.2507 - 1.969 0.275 - 94.8 1 2 0 -0.0005 19 0 0 0 4.47E+06 2.30E+06 - - - 3.2704 1 221125_WJC_METTL3_EV_vs_WT_F07.17659.17659.4 1.57E-13 21/90 R.RGFC[160.03]FITYTDEEPVKK.L "sp|O14979|HNRDL_HUMAN,tr|A0A087WUK2|A0A087WUK2_HUMAN" 2 1988.9666 1.2 103981 17659 4 1988.973429 498.2489 Heterogeneous nuclear ribonucleoprotein D-like OS=Homo sapiens OX=9606 GN=HNRNPDL PE=1 SV=3 6.17 2940.7 - 1.35E+06 - - - 3.4339 - 3.363 0.678 - 353.7 1 2 0 0.0068 16 0 0 0 6.83E+07 5.70E+07 - - - 5.5527 1 221125_WJC_METTL3_EV_vs_WT_F07.17660.17660.4 1.04E-10 19/90 R.R[166.11]GFC[160.03]FITYTDEEPVK[136.11]K[136.11].L "sp|O14979|HNRDL_HUMAN,tr|A0A087WUK2|A0A087WUK2_HUMAN" 2 2015.0033 1.2 103982 17660 4 2015.008518 504.7581 Heterogeneous nuclear ribonucleoprotein D-like OS=Homo sapiens OX=9606 GN=HNRNPDL PE=1 SV=3 6.17 2940.8 - 1.45E+06 - - - 2.605 - 2.892 0.654 - 265.4 1 2 0 0.0052 16 0 0 0 6.83E+07 5.70E+07 - - - 5.291 1 221125_WJC_METTL3_EV_vs_WT_F07.17662.17662.3 3.20E-10 19/60 R.R[166.11]GFC[160.03]FITYTDEEPVK[136.11]K[136.11].L "sp|O14979|HNRDL_HUMAN,tr|A0A087WUK2|A0A087WUK2_HUMAN" 2 2015.0033 1.22 103984 17662 3 2015.008248 672.675 Heterogeneous nuclear ribonucleoprotein D-like OS=Homo sapiens OX=9606 GN=HNRNPDL PE=1 SV=3 6.17 2940.9 - 944735 - - - 2.471 - 3.514 0.592 - 564.8 1 2 0 0.005 16 0 0 0 5.36E+07 4.39E+07 - - - 8.3635 0.9996 221125_WJC_METTL3_EV_vs_WT_F07.17663.17663.4 1.45E-09 26/120 R.IC[160.03]NAVSPDKDVDGFHVINVGR.M "sp|P13995|MTDC_HUMAN,tr|A0A7I2V482|A0A7I2V482_HUMAN,tr|A0A7I2V2U6|A0A7I2V2U6_HUMAN,tr|A0A7I2YQD4|A0A7I2YQD4_HUMAN,tr|B8ZZU9|B8ZZU9_HUMAN" 5 2311.1379 1.16 103985 17663 4 2311.147508 578.7918 "Bifunctional methylenetetrahydrofolate dehydrogenase\cyclohydrolase, mitochondrial OS=Homo sapiens OX=9606 GN=MTHFD2 PE=1 SV=2" 5.3 2941.1 - 900107 - - - 4.1508 - 4.41 0.606 - 520 1 2 1 0.0096 21 0 0 0 1.31E+08 1.13E+08 - - - 4.9886 0.9997 221125_WJC_METTL3_EV_vs_WT_F07.17665.17665.4 3.14E-06 14/96 R.NVESGEEELASKLDHYK.A sp|Q96HS1|PGAM5_HUMAN 1 1946.9222 1.42 103987 17665 4 1946.927469 487.7378 "Serine\threonine-protein phosphatase PGAM5, mitochondrial OS=Homo sapiens OX=9606 GN=PGAM5 PE=1 SV=2" 4.57 2941.3 - 623055 - - - 2.7315 - 3.027 0.499 - 143.8 1 2 1 0.0053 17 0 0 0 9.51E+06 6.68E+06 - - - 3.9524 0.9996 221125_WJC_METTL3_EV_vs_WT_F07.17667.17667.4 3.45E-06 14/96 K.NTEK[136.11]ENATVAHLVGALR[166.11].S sp|Q13158|FADD_HUMAN 1 1839.9922 1.33 103989 17667 4 1839.995438 461.0053 FAS-associated death domain protein OS=Homo sapiens OX=9606 GN=FADD PE=1 SV=1 6.76 2941.5 - 432929 - - - 1.7707 - 2.409 0.441 - 171.6 1 2 1 0.0033 17 0 0 0 6.73E+06 5.07E+06 - - - 3.3688 0.9999 221125_WJC_METTL3_EV_vs_WT_F07.17668.17668.4 2.36E-07 15/96 R.NVESGEEELASK[136.11]LDHYK[136.11].A sp|Q96HS1|PGAM5_HUMAN 1 1962.9506 1.44 103990 17668 4 1962.954703 491.7449 "Serine\threonine-protein phosphatase PGAM5, mitochondrial OS=Homo sapiens OX=9606 GN=PGAM5 PE=1 SV=2" 4.57 2941.6 - 422576 - - - 2.1152 - 2.924 0.576 - 202.3 1 2 1 0.0042 17 0 0 0 9.69E+06 6.71E+06 - - - 4.6109 0.9987 221125_WJC_METTL3_EV_vs_WT_F07.17669.17669.4 0.000149 15/96 K.NTEKENATVAHLVGALR.S sp|Q13158|FADD_HUMAN 1 1821.9697 1.34 103991 17669 4 1821.974159 456.4997 FAS-associated death domain protein OS=Homo sapiens OX=9606 GN=FADD PE=1 SV=1 6.76 2941.8 - 403480 - - - 2.4419 - 2.364 0.394 - 191.3 1 2 1 0.0044 17 0 0 0 6.80E+06 5.07E+06 - - - 2.9529 1 221125_WJC_METTL3_EV_vs_WT_F07.17675.17675.4 2.80E-11 25/120 R.IC[160.03]NAVSPDK[136.11]DVDGFHVINVGR[166.11].M "sp|P13995|MTDC_HUMAN,tr|A0A7I2V482|A0A7I2V482_HUMAN,tr|A0A7I2V2U6|A0A7I2V2U6_HUMAN,tr|A0A7I2YQD4|A0A7I2YQD4_HUMAN,tr|B8ZZU9|B8ZZU9_HUMAN" 5 2329.1604 1.16 103995 17675 4 2329.164817 583.2974 "Bifunctional methylenetetrahydrofolate dehydrogenase\cyclohydrolase, mitochondrial OS=Homo sapiens OX=9606 GN=MTHFD2 PE=1 SV=2" 5.3 2942.5 - 2.34E+06 - - - 1.9028 - 4.068 0.663 - 486.7 1 2 1 0.0044 21 0 0 0 1.31E+08 1.13E+08 - - - 5.4595 0.7829 221125_WJC_METTL3_EV_vs_WT_F07.17676.17676.3 0.00177 16/72 R.HPHDIIDDINSGAVEC[160.03]PAS.- sp|P30050|RL12_HUMAN 1 2045.9113 - 103996 17676 3 2046.897101 682.9777 60S ribosomal protein L12 OS=Homo sapiens OX=9606 GN=RPL12 PE=1 SV=1 4.21 2942.6 - 681196 - - - 481.8547 - 2.555 0.441 - 266.4 1 2 0 0.9858 19 0 0 0 - - - - - 5.4882 0.9993 221125_WJC_METTL3_EV_vs_WT_F07.17678.17678.3 0.000113 Dec-60 K.STTSDIPHMLNQVESK[136.11].V "sp|Q52LJ0|FA98B_HUMAN,tr|H0YNA1|H0YNA1_HUMAN" 2 1793.8709 4.03 103998 17678 3 1793.876368 598.9642 Protein FAM98B OS=Homo sapiens OX=9606 GN=FAM98B PE=1 SV=2 5.3 2942.9 - 515982 - - - 3.0404 - 2.231 0.37 - 166.9 1 2 0 0.0055 16 0 0 0 2.33E+08 5.79E+07 - - - 4.7226 0.9811 221125_WJC_METTL3_EV_vs_WT_F07.17679.17679.3 0.000769 Dec-76 K.NVPQEEEIMPPNSLPSNNSR[166.11].V "sp|Q06787|FMR1_HUMAN,tr|A8MQB8|A8MQB8_HUMAN,tr|A0A087WXI3|A0A087WXI3_HUMAN,tr|G3V0J0|G3V0J0_HUMAN" 4 2261.0622 2.01 103999 17679 3 2261.081065 754.6947 Synaptic functional regulator FMR1 OS=Homo sapiens OX=9606 GN=FMR1 PE=1 SV=1 4.25 2943 - 360774 - - - 8.3523 - 2.267 0.364 - 129.4 1 2 0 0.0189 20 0 0 0 1.22E+08 6.08E+07 - - - 4.5786 0.9996 221125_WJC_METTL3_EV_vs_WT_F07.17682.17682.3 0.000244 8/100 R.QPPAR[166.11]PPGPSTDTGALADGVVSQAVK[136.11].E sp|Q92917|GPKOW_HUMAN 1 2533.3255 2.04 104002 17682 3 2533.32958 845.4491 G-patch domain and KOW motifs-containing protein OS=Homo sapiens OX=9606 GN=GPKOW PE=1 SV=2 5.96 2943.4 - 163294 - - - 1.5963 - 1.698 0.407 - 45.1 1 2 0 0.004 26 0 0 0 6.26E+06 3.07E+06 - - - 4.2946 1 221125_WJC_METTL3_EV_vs_WT_F07.17684.17684.3 2.62E-12 20/60 R.RGFC[160.03]FITYTDEEPVKK.L "sp|O14979|HNRDL_HUMAN,tr|A0A087WUK2|A0A087WUK2_HUMAN" 2 1988.9666 1.22 104003 17684 3 1988.971495 663.9961 Heterogeneous nuclear ribonucleoprotein D-like OS=Homo sapiens OX=9606 GN=HNRNPDL PE=1 SV=3 6.17 2943.6 - 3.61E+06 - - - 2.4616 - 4.002 0.667 - 550 1 2 0 0.0049 16 0 0 0 5.36E+07 4.39E+07 - - - 9.5334 1 221125_WJC_METTL3_EV_vs_WT_F07.17689.17689.4 8.98E-07 16/90 R.DLK[136.11]PENILLDDHGHIR[166.11].L "sp|P43250|GRK6_HUMAN,tr|D6RHX8|D6RHX8_HUMAN,tr|F8W9W2|F8W9W2_HUMAN" 3 1902.0078 0.98 104007 17689 4 1902.010207 476.5092 G protein-coupled receptor kinase 6 OS=Homo sapiens OX=9606 GN=GRK6 PE=1 SV=2 5.26 2944.2 - 530880 - - - 1.2497 - 2.717 0.49 - 197 1 2 0 0.0024 16 0 0 0 4.91E+06 5.03E+06 - - - 3.8424 1 221125_WJC_METTL3_EV_vs_WT_F07.17690.17690.3 3.42E-10 19/68 R.K[136.11]DEELDPMDPSSYSDAPR[166.11].G "sp|O60828|PQBP1_HUMAN,tr|H7C053|H7C053_HUMAN" 2 2068.9014 1.19 104008 17690 3 2068.904236 690.6411 Polyglutamine-binding protein 1 OS=Homo sapiens OX=9606 GN=PQBP1 PE=1 SV=1 3.96 2944.3 - 501992 - - - 1.3539 - 3.522 0.632 - 590.9 1 2 0 0.0028 18 0 0 0 1.89E+07 1.59E+07 - - - 8.7205 1 221125_WJC_METTL3_EV_vs_WT_F07.17692.17692.3 4.79E-09 22/72 R.GSDALSETSSVSHIEDLEK.V "sp|Q6P996|PDXD1_HUMAN,tr|H3BND4|H3BND4_HUMAN" 2 2002.9331 1.06 104010 17692 3 2002.93553 668.6516 Pyridoxal-dependent decarboxylase domain-containing protein 1 OS=Homo sapiens OX=9606 GN=PDXDC1 PE=1 SV=2 4.17 2944.6 - 496589 - - - 1.2087 - 3.605 0.555 - 429.7 1 2 0 0.0024 19 0 0 0 6.49E+06 6.12E+06 - - - 7.8774 0.9999 221125_WJC_METTL3_EV_vs_WT_F07.17695.17695.3 1.73E-06 12/100 R.QPPARPPGPSTDTGALADGVVSQAVK.E sp|Q92917|GPKOW_HUMAN 1 2515.3031 2.04 104013 17695 3 2515.308055 839.4416 G-patch domain and KOW motifs-containing protein OS=Homo sapiens OX=9606 GN=GPKOW PE=1 SV=2 5.96 2945 - 334382 - - - 1.9835 - 2.084 0.481 - 119.4 1 2 0 0.005 26 0 0 0 6.26E+06 3.07E+06 - - - 5.5906 1 221125_WJC_METTL3_EV_vs_WT_F07.17700.17700.3 0.000121 22/76 K.NVPQEEEIMPPNSLPSNNSR.V "sp|Q06787|FMR1_HUMAN,tr|A8MQB8|A8MQB8_HUMAN,tr|A0A087WXI3|A0A087WXI3_HUMAN,tr|G3V0J0|G3V0J0_HUMAN" 4 2251.0539 2.01 104016 17700 3 2251.052663 751.3586 Synaptic functional regulator FMR1 OS=Homo sapiens OX=9606 GN=FMR1 PE=1 SV=1 4.25 2945.6 - 1.05E+06 - - - -0.554 - 3.305 0.5 - 341.8 1 2 0 -0.0012 20 0 0 0 1.22E+08 6.08E+07 - - - 7.0143 1 221125_WJC_METTL3_EV_vs_WT_F07.17703.17703.3 3.55E-12 28/88 R.GNFGGSFAGSFGGAGGHAPGVAR[166.11].K "sp|P52272|HNRPM_HUMAN,tr|M0R2I7|M0R2I7_HUMAN,tr|M0QY96|M0QY96_HUMAN,tr|A0A087X0X3|A0A087X0X3_HUMAN" 4 2043.9539 2.09 104019 17703 3 2043.956132 682.3252 Heterogeneous nuclear ribonucleoprotein M OS=Homo sapiens OX=9606 GN=HNRNPM PE=1 SV=3 9.76 2945.8 - 1.95E+06 - - - 1.0969 - 4.833 0.71 - 899.1 1 2 0 0.0022 23 0 0 0 7.59E+07 3.63E+07 - - - 10.1511 1 221125_WJC_METTL3_EV_vs_WT_F07.17704.17704.3 3.71E-09 27/80 R.IC[160.03]NAVSPDKDVDGFHVINVGR.M "sp|P13995|MTDC_HUMAN,tr|A0A7I2V482|A0A7I2V482_HUMAN,tr|A0A7I2V2U6|A0A7I2V2U6_HUMAN,tr|A0A7I2YQD4|A0A7I2YQD4_HUMAN,tr|B8ZZU9|B8ZZU9_HUMAN" 5 2311.1379 1.83 104020 17704 3 2311.144977 771.3866 "Bifunctional methylenetetrahydrofolate dehydrogenase\cyclohydrolase, mitochondrial OS=Homo sapiens OX=9606 GN=MTHFD2 PE=1 SV=2" 5.3 2946 - 1.16E+06 - - - 3.0556 - 5.524 0.666 - 1080.1 1 2 1 0.0071 21 0 0 0 2.30E+07 1.26E+07 - - - 10.0608 0.9994 221125_WJC_METTL3_EV_vs_WT_F07.17707.17707.3 0.000512 15/68 R.RSLGYAYVNFQQPADAER.A "sp|Q13310|PABP4_HUMAN,sp|P11940|PABP1_HUMAN,tr|A0A7I2V649|A0A7I2V649_HUMAN,tr|B1ANR0|B1ANR0_HUMAN,tr|A0A7I2V4L7|A0A7I2V4L7_HUMAN,tr|E5RHG7|E5RHG7_HUMAN,tr|B1ANR1|B1ANR1_HUMAN,tr|H0YAR2|H0YAR2_HUMAN,tr|E7ERJ7|E7ERJ7_HUMAN,tr|E5RJB9|E5RJB9_HUMAN,tr|A0A7I2YQ88|A0A7I2YQ88_HUMAN,tr|E5RH24|E5RH24_HUMAN,tr|H0YBN4|H0YBN4_HUMAN,tr|E5RGH3|E5RGH3_HUMAN,tr|A0A087WTT1|A0A087WTT1_HUMAN,tr|A0A7I2YQ90|A0A7I2YQ90_HUMAN,tr|E7EQV3|E7EQV3_HUMAN" 17 2084.0076 1.27 104023 17707 3 2084.017319 695.6765 Polyadenylate-binding protein 4 OS=Homo sapiens OX=9606 GN=PABPC4 PE=1 SV=1 6.07 2946.3 - 467811 - - - 4.6866 - 2.855 0.436 - 257.9 1 2 0 0.0098 18 0 0 0 4.83E+06 3.80E+06 - - - 6.0106 0.9885 221125_WJC_METTL3_EV_vs_WT_F07.17708.17708.3 0.0158 Aug-56 R.SDRREDYYDIQLSIK.G "sp|Q93009|UBP7_HUMAN,tr|A0A669KBL1|A0A669KBL1_HUMAN,tr|F5H2X1|F5H2X1_HUMAN,tr|H3BND8|H3BND8_HUMAN" 4 1899.9327 1.5 104024 17708 3 1899.937739 634.3182 Ubiquitin carboxyl-terminal hydrolase 7 OS=Homo sapiens OX=9606 GN=USP7 PE=1 SV=2 4.68 2946.5 - 352520 - - - 2.6754 - 1.695 0.317 - 74.2 1 2 1 0.0051 15 0 0 0 4.92E+06 3.29E+06 - - - 3.4497 1 221125_WJC_METTL3_EV_vs_WT_F07.17715.17715.3 1.07E-14 26/88 R.YAAQENLEYNVEPQEISHPDVGR[166.11].Y "sp|O94952|FBX21_HUMAN,tr|Q4G104|Q4G104_HUMAN,tr|H0YIE9|H0YIE9_HUMAN" 3 2667.244 0.01 104029 17715 3 2667.243711 890.0886 F-box only protein 21 OS=Homo sapiens OX=9606 GN=FBXO21 PE=2 SV=2 4.25 2947.4 - 682588 - - - -0.1248 - 4.088 0.675 - 791.4 1 2 0 -0.0003 23 0 0 0 1.95E+05 1.79E+07 - - - 9.3687 1 221125_WJC_METTL3_EV_vs_WT_F07.17718.17718.4 1.16E-12 29/204 R.AAAAAAGGGYTAMPAPMSVYSHPAHAEQYPGGMAR.A sp|Q12948|FOXC1_HUMAN 1 3416.5489 2.64 104032 17718 4 3416.547903 855.1445 Forkhead box protein C1 OS=Homo sapiens OX=9606 GN=FOXC1 PE=1 SV=3 6.96 2947.7 - 452672 - - - -0.2874 - 4.122 0.667 - 334.8 1 2 0 -0.001 35 0 0 0 9.55E+06 3.62E+06 - - - 5.4512 0.9998 221125_WJC_METTL3_EV_vs_WT_F07.17723.17723.4 0.0695 19/120 K.IC[160.03]ANHYITPMMELK[136.11]PNAGSDR[166.11].A "sp|P43487|RANG_HUMAN,tr|C9JXG8|C9JXG8_HUMAN,tr|F6WQW2|F6WQW2_HUMAN,tr|C9JGV6|C9JGV6_HUMAN,tr|C9JJ34|C9JJ34_HUMAN" 5 2435.1515 2.32 104035 17723 4 2435.153521 609.7951 Ran-specific GTPase-activating protein OS=Homo sapiens OX=9606 GN=RANBP1 PE=1 SV=1 6.74 2948.4 - 838036 - - - 0.8398 - 2.979 0.384 - 183.5 1 2 0 0.002 21 0 0 0 4.52E+07 1.94E+07 - - - 2.9287 0.9986 221125_WJC_METTL3_EV_vs_WT_F07.17724.17724.4 0.00188 12/102 K.RPLDDGVGNQLGALVHQR.T sp|Q96I24|FUBP3_HUMAN 1 1944.029 2.88 104036 17724 4 1944.031537 487.0145 Far upstream element-binding protein 3 OS=Homo sapiens OX=9606 GN=FUBP3 PE=1 SV=2 6.75 2948.5 - 411700 - - - 1.3277 - 2.063 0.282 - 76.4 1 2 0 0.0026 18 0 0 0 7.04E+06 2.45E+06 - - - 1.9279 0.9946 221125_WJC_METTL3_EV_vs_WT_F07.17729.17729.4 0.000716 19/204 R.AAAAAAGGGYTAMPAPMSVYSHPAHAEQYPGGMAR[166.11].A sp|Q12948|FOXC1_HUMAN 1 3426.5572 2.64 104041 17729 4 3427.563334 857.6466 Forkhead box protein C1 OS=Homo sapiens OX=9606 GN=FOXC1 PE=1 SV=3 6.96 2949.1 - 289922 - - - 293.6414 - 2.294 0.414 - 57.8 1 2 0 1.0062 35 0 0 0 9.55E+06 3.62E+06 - - - 2.7969 1 221125_WJC_METTL3_EV_vs_WT_F07.17733.17733.3 1.66E-17 23/88 K.KAAAPAPEEEMDEC[160.03]EQALAAEPK.A sp|P26641|EF1G_HUMAN 1 2484.1149 0.99 104043 17733 3 2484.110491 829.0456 Elongation factor 1-gamma OS=Homo sapiens OX=9606 GN=EEF1G PE=1 SV=3 4.06 2949.6 - 754407 - - - -1.7572 - 4.47 0.792 - 503.4 1 2 0 -0.0044 23 0 0 0 7.13E+07 7.21E+07 - - - 10.8816 1 221125_WJC_METTL3_EV_vs_WT_F07.17739.17739.4 3.23E-10 20/114 K.NDTAAVQLHFVSGNNVLAHR.S sp|Q96T58|MINT_HUMAN 1 2162.0981 0.84 104047 17739 4 2162.102049 541.5318 Msx2-interacting protein OS=Homo sapiens OX=9606 GN=SPEN PE=1 SV=1 6.92 2950.5 - 725408 - - - 1.8274 - 4.421 0.631 - 255.9 1 2 0 0.004 20 0 0 0 1.86E+07 2.22E+07 - - - 5.2141 0.9996 221125_WJC_METTL3_EV_vs_WT_F07.17742.17742.4 0.000286 14/114 K.NDTAAVQLHFVSGNNVLAHR[166.11].S sp|Q96T58|MINT_HUMAN 1 2172.1064 0.83 104050 17742 4 2172.102642 544.0339 Msx2-interacting protein OS=Homo sapiens OX=9606 GN=SPEN PE=1 SV=1 6.92 2950.8 - 1.09E+06 - - - -1.7154 - 2.379 0.345 - 99 1 2 0 -0.0037 20 0 0 0 1.88E+07 2.25E+07 - - - 2.5176 1 221125_WJC_METTL3_EV_vs_WT_F07.17747.17747.2 1.20E-09 14/38 K.NVPQEEEIMPPNSLPSNNSR.V "sp|Q06787|FMR1_HUMAN,tr|A8MQB8|A8MQB8_HUMAN,tr|A0A087WXI3|A0A087WXI3_HUMAN,tr|G3V0J0|G3V0J0_HUMAN" 4 2251.0539 2.69 104055 17747 2 2251.05507 1126.5342 Synaptic functional regulator FMR1 OS=Homo sapiens OX=9606 GN=FMR1 PE=1 SV=1 4.25 2951.4 - 352202 - - - 0.5153 - 2.651 0.654 - 210.5 1 2 0 0.0012 20 0 0 0 1.13E+07 4.21E+06 - - - 6.268 0.7941 221125_WJC_METTL3_EV_vs_WT_F07.17752.17752.4 0.554 11/138 R.EPR[166.11]THLAYALDLGSSPVPSSTAPK[136.11].T sp|Q9H1K0|RBNS5_HUMAN 1 2511.3088 0.01 104058 17752 4 2511.313623 628.8345 Rabenosyn-5 OS=Homo sapiens OX=9606 GN=RBSN PE=1 SV=2 6.85 2952.1 - 737867 - - - 1.9114 - 1.722 0.147 - 50.6 1 2 1 0.0048 24 0 0 0 5.90E+04 9.95E+06 - - - 0.6786 0.9999 221125_WJC_METTL3_EV_vs_WT_F07.17754.17754.3 2.53E-06 16/68 K.YVHYEIDAC[160.03]MDSEAPGSK[136.11].D "sp|Q86U44|MTA70_HUMAN,tr|H0YFV6|H0YFV6_HUMAN" 2 2078.8805 0.001 104060 17754 3 2078.873857 693.9674 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 4.31 2952.4 - 471462 - - - -3.1916 - 2.822 0.531 - 294.4 1 2 0 -0.0066 18 0 0 0 0.00E+00 1.12E+07 - - - 7.0416 0.9968 221125_WJC_METTL3_EV_vs_WT_F07.17755.17755.4 7.51E-08 16/150 H.VIHHTTVVQPNSIPSAIYPAPVAAPR[166.11].T sp|Q92567|F168A_HUMAN 1 2744.5001 7.81 104061 17755 4 2744.500912 687.1323 Protein FAM168A OS=Homo sapiens OX=9606 GN=FAM168A PE=1 SV=2 8.73 2952.5 - 266431 - - - 0.2817 - 2.8 0.529 - 121.3 1 1 0 0.0008 26 0 0 0 1.64E+07 2.10E+06 - - - 4.155 0.9998 221125_WJC_METTL3_EV_vs_WT_F07.17759.17759.3 3.86E-05 16/76 K.NDTAAVQLHFVSGNNVLAHR[166.11].S sp|Q96T58|MINT_HUMAN 1 2172.1064 -1 104063 17759 3 2172.098748 725.0427 Msx2-interacting protein OS=Homo sapiens OX=9606 GN=SPEN PE=1 SV=1 6.92 2953 - 718874 - - - -3.5081 - 3.099 0.473 - 206.7 1 2 0 -0.0076 20 0 0 0 0.00E+00 0.00E+00 - - - 6.5554 0.9976 221125_WJC_METTL3_EV_vs_WT_F07.17760.17760.4 0.00493 15/114 K.K[136.11]LGEMWNNLNDSEK[136.11]QPYITK[136.11].A "sp|O15347|HMGB3_HUMAN,tr|E9PES6|E9PES6_HUMAN,tr|E7EQU1|E7EQU1_HUMAN,tr|E7ES08|E7ES08_HUMAN" 4 2431.2268 0.18 104064 17760 4 2431.231029 608.814 High mobility group protein B3 OS=Homo sapiens OX=9606 GN=HMGB3 PE=1 SV=4 6.18 2953.1 - 870055 - - - 1.7411 - 2.619 0.328 - 125.2 1 2 1 0.0042 20 0 0 0 1.15E+06 6.54E+06 - - - 2.4016 0.9976 221125_WJC_METTL3_EV_vs_WT_F07.17762.17762.4 0.000777 13/126 M.VKETTYYDVLGVKPNATQEELK.K sp|P31689|DNJA1_HUMAN 1 2524.3061 0.48 104066 17762 4 2524.317755 632.0838 DnaJ homolog subfamily A member 1 OS=Homo sapiens OX=9606 GN=DNAJA1 PE=1 SV=2 4.87 2953.4 - 396940 - - - 4.6231 - 3.052 0.452 - 63.9 1 2 1 0.0117 22 0 0 0 5.04E+06 1.04E+07 - - - 3.5221 0.9897 221125_WJC_METTL3_EV_vs_WT_F07.17763.17763.3 0.000277 Aug-72 K.QEPGSNEEIKEFAAGYNVK.F "sp|P36969|GPX4_HUMAN,tr|A0A087X2I2|A0A087X2I2_HUMAN,tr|A0A0A0MTT1|A0A0A0MTT1_HUMAN,tr|K7EKX7|K7EKX7_HUMAN,tr|K7ERP4|K7ERP4_HUMAN,tr|K7ENB4|K7ENB4_HUMAN,tr|R4GNE4|R4GNE4_HUMAN,tr|A0A087WT12|A0A087WT12_HUMAN,tr|K7EJ20|K7EJ20_HUMAN" 9 2109.0015 0.31 104067 17763 3 2109.011452 704.0078 Phospholipid hydroperoxide glutathione peroxidase OS=Homo sapiens OX=9606 GN=GPX4 PE=1 SV=3 4.49 2953.5 - 340368 - - - 4.7359 - 2.217 0.38 - 71.2 1 2 1 0.01 19 0 0 0 2.15E+06 6.89E+06 - - - 4.7299 0.9999 221125_WJC_METTL3_EV_vs_WT_F07.17764.17764.4 0.00024 19/102 K.R[166.11]PLDDGVGNQLGALVHQR[166.11].T sp|Q96I24|FUBP3_HUMAN 1 1964.0455 2.35 104068 17764 4 1964.042946 492.0187 Far upstream element-binding protein 3 OS=Homo sapiens OX=9606 GN=FUBP3 PE=1 SV=2 6.75 2953.6 - 198146 - - - -1.2983 - 3.251 0.445 - 377.4 1 2 0 -0.0026 18 0 0 0 2.06E+07 8.77E+06 - - - 3.5024 1 221125_WJC_METTL3_EV_vs_WT_F07.17768.17768.4 5.74E-10 24/144 R.NQLSTAASLGPSGLQNHGQHLILSR.E "sp|Q96JN0|LCOR_HUMAN,tr|A0A6Q8PH28|A0A6Q8PH28_HUMAN,tr|A0A6Q8PG83|A0A6Q8PG83_HUMAN,tr|A0A6Q8PFQ9|A0A6Q8PFQ9_HUMAN,tr|A0A6Q8PGR8|A0A6Q8PGR8_HUMAN,tr|A0A6Q8PGL8|A0A6Q8PGL8_HUMAN,tr|A0A6Q8PFM9|A0A6Q8PFM9_HUMAN" 7 2598.3626 2.6 104070 17768 4 2598.365331 650.5979 Ligand-dependent corepressor OS=Homo sapiens OX=9606 GN=LCOR PE=1 SV=2 9.76 2954.2 - 742670 - - - 1.0333 - 4.417 0.556 - 363.4 1 2 0 0.0027 25 0 0 0 1.82E+07 7.00E+06 - - - 4.5372 0.9999 221125_WJC_METTL3_EV_vs_WT_F07.17770.17770.4 0.000171 14/102 K.K[136.11]QGGLGPMNIPLVSDPK[136.11]R[166.11].T "sp|Q06830|PRDX1_HUMAN,tr|A0A0A0MSI0|A0A0A0MSI0_HUMAN" 2 1932.0825 0.64 104072 17770 4 1932.086182 484.0279 Peroxiredoxin-1 OS=Homo sapiens OX=9606 GN=PRDX1 PE=1 SV=1 9.99 2954.4 - 341195 - - - 1.8943 - 2.568 0.439 - 160.2 1 2 0 0.0037 18 0 0 0 4.69E+07 7.30E+07 - - - 3.3691 0.999 221125_WJC_METTL3_EV_vs_WT_F07.17771.17771.3 0.00409 14/68 K.DGDK[136.11]DVFASEVTPSDLQK[136.11].Q sp|Q8WYP5|ELYS_HUMAN 1 1965.9502 0.95 104073 17771 3 1965.952129 656.324 Protein ELYS OS=Homo sapiens OX=9606 GN=AHCTF1 PE=1 SV=3 4.04 2954.6 - 296668 - - - 0.9731 - 2.391 0.347 - 211.8 1 2 1 0.0019 18 0 0 0 4.55E+06 4.78E+06 - - - 4.5788 0.9998 221125_WJC_METTL3_EV_vs_WT_F07.17772.17772.2 1.12E-05 Sep-38 K.NVPQEEEIMPPNSLPSNNSR[166.11].V "sp|Q06787|FMR1_HUMAN,tr|A8MQB8|A8MQB8_HUMAN,tr|A0A087WXI3|A0A087WXI3_HUMAN,tr|G3V0J0|G3V0J0_HUMAN" 4 2261.0622 2.69 104074 17772 2 2261.063928 1131.5384 Synaptic functional regulator FMR1 OS=Homo sapiens OX=9606 GN=FMR1 PE=1 SV=1 4.25 2954.7 - 242947 - - - 0.7731 - 1.888 0.529 - 113.5 1 2 0 0.0017 20 0 0 0 1.13E+07 4.21E+06 - - - 4.5101 1 221125_WJC_METTL3_EV_vs_WT_F07.17776.17776.3 3.69E-10 17/108 Y.GAQGSSLASYGNQPSSYGAQAASSYGVR[166.11].A sp|Q96PK6|RBM14_HUMAN 1 2730.2509 1.48 104077 17776 3 2730.249958 911.0909 RNA-binding protein 14 OS=Homo sapiens OX=9606 GN=RBM14 PE=1 SV=2 8.5 2955.2 - 395208 - - - -0.3523 - 3.087 0.688 - 275.3 1 1 0 -0.001 28 0 0 0 9.23E+06 6.22E+06 - - - 8.8035 1 221125_WJC_METTL3_EV_vs_WT_F07.17777.17777.3 1.41E-16 24/108 Y.GAQGSSLASYGNQPSSYGAQAASSYGVR.A sp|Q96PK6|RBM14_HUMAN 1 2720.2427 1.48 104078 17777 3 2720.246546 907.7548 RNA-binding protein 14 OS=Homo sapiens OX=9606 GN=RBM14 PE=1 SV=2 8.5 2955.3 - 785503 - - - 1.4322 - 4.414 0.672 - 561.3 1 1 0 0.0039 28 0 0 0 9.23E+06 6.22E+06 - - - 9.447 0.9987 221125_WJC_METTL3_EV_vs_WT_F07.17783.17783.3 4.17E-08 19/76 R.TDGSISGDRQPVTVADYISR.A sp|P51116|FXR2_HUMAN 1 2136.0447 0.76 104082 17783 3 2136.056575 713.0222 Fragile X mental retardation syndrome-related protein 2 OS=Homo sapiens OX=9606 GN=FXR2 PE=1 SV=2 4.43 2956 - 953841 - - - 5.5476 - 3.575 0.572 - 458.4 1 2 1 0.0118 20 0 0 0 2.20E+07 2.90E+07 - - - 8.0046 1 221125_WJC_METTL3_EV_vs_WT_F07.17784.17784.3 1.49E-07 17/112 R.AFSTVPLTPVPRPSDSVSSTPAATSTPSK.Q "sp|Q9ULV3|CIZ1_HUMAN,tr|Q5SYW2|Q5SYW2_HUMAN,tr|F5H2X7|F5H2X7_HUMAN,tr|H0Y5D5|H0Y5D5_HUMAN,tr|A0A494C0L7|A0A494C0L7_HUMAN,tr|Q9BTG3|Q9BTG3_HUMAN" 6 2884.4818 3.18 104083 17784 3 2884.486004 962.5012 Cip1-interacting zinc finger protein OS=Homo sapiens OX=9606 GN=CIZ1 PE=1 SV=2 8.79 2956.2 - 599583 - - - 1.4512 - 2.902 0.552 - 142.8 1 2 0 0.0042 29 0 0 0 2.71E+07 8.52E+06 - - - 7.1442 0.9999 221125_WJC_METTL3_EV_vs_WT_F07.17786.17786.3 0.000203 11/112 R.AFSTVPLTPVPR[166.11]PSDSVSSTPAATSTPSK[136.11].Q "sp|Q9ULV3|CIZ1_HUMAN,tr|Q5SYW2|Q5SYW2_HUMAN,tr|F5H2X7|F5H2X7_HUMAN,tr|H0Y5D5|H0Y5D5_HUMAN,tr|A0A494C0L7|A0A494C0L7_HUMAN,tr|Q9BTG3|Q9BTG3_HUMAN" 6 2902.5043 3.18 104085 17786 3 2902.508833 968.5087 Cip1-interacting zinc finger protein OS=Homo sapiens OX=9606 GN=CIZ1 PE=1 SV=2 8.79 2956.4 - 223626 - - - 1.5659 - 1.964 0.493 - 53.6 1 2 0 0.0045 29 0 0 0 2.71E+07 8.52E+06 - - - 5.5881 1 221125_WJC_METTL3_EV_vs_WT_F07.17787.17787.4 7.43E-06 Oct-84 R.AHQVVEDGYEFFAK[136.11]R[166.11].Q "sp|P62136|PP1A_HUMAN,sp|P62140|PP1B_HUMAN,sp|P36873|PP1G_HUMAN,tr|A0A7I2V4F7|A0A7I2V4F7_HUMAN,tr|F8W0W8|F8W0W8_HUMAN,tr|F8VYE8|F8VYE8_HUMAN,tr|E9PMD7|E9PMD7_HUMAN" 7 1812.8914 0.75 104086 17787 4 1812.890268 454.2301 Serine\threonine-protein phosphatase PP1-alpha catalytic subunit OS=Homo sapiens OX=9606 GN=PPP1CA PE=1 SV=1 5.45 2956.5 - 144963 - - - -0.6261 - 2.17 0.554 - 76.7 1 2 0 -0.0011 15 0 0 0 2.07E+06 2.76E+06 - - - 4.3249 1 221125_WJC_METTL3_EV_vs_WT_F07.17793.17793.3 7.83E-11 21/84 K.DK[136.11]GGINLTATC[160.03]PQSELDAETVK[136.11].S sp|Q9Y295|DRG1_HUMAN 1 2362.1657 0.39 104090 17793 3 2362.174832 788.3958 Developmentally-regulated GTP-binding protein 1 OS=Homo sapiens OX=9606 GN=DRG1 PE=1 SV=1 4.32 2957.2 - 634998 - - - 3.8634 - 4.044 0.63 - 567.9 1 2 1 0.0091 22 0 0 0 7.44E+06 1.89E+07 - - - 8.874 1 221125_WJC_METTL3_EV_vs_WT_F07.17796.17796.4 2.59E-12 19/108 K.MNLASEPQEVLHIGSAHNR[166.11].S sp|O00151|PDLI1_HUMAN 1 2112.041 0.99 104093 17796 4 2112.041877 529.0175 PDZ and LIM domain protein 1 OS=Homo sapiens OX=9606 GN=PDLIM1 PE=1 SV=4 5.96 2957.6 - 433494 - - - 0.4195 - 4.028 0.613 - 268.6 1 2 0 0.0009 19 0 0 0 6.71E+06 6.79E+06 - - - 5.0326 0.9997 221125_WJC_METTL3_EV_vs_WT_F07.17798.17798.3 8.32E-07 Nov-84 R.INSQLVAQQVAQQYATPPPPKK.E sp|Q8N488|RYBP_HUMAN 1 2405.3067 1.86 104095 17798 3 2405.316538 802.7762 RING1 and YY1-binding protein OS=Homo sapiens OX=9606 GN=RYBP PE=1 SV=2 9.7 2957.9 - 211426 - - - 4.0926 - 2.283 0.534 - 104.1 1 2 0 0.0098 22 0 0 0 1.81E+06 9.73E+05 - - - 6.4479 0.9999 221125_WJC_METTL3_EV_vs_WT_F07.17802.17802.4 7.33E-06 15/108 R.GLLQDDAHPTLVTYADHSK[136.11].L "sp|Q86U44|MTA70_HUMAN,tr|F5H6D8|F5H6D8_HUMAN,tr|H0YFV6|H0YFV6_HUMAN,tr|B4DTN4|B4DTN4_HUMAN" 4 2088.0367 0.02 104097 17802 4 2088.041206 523.0165 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 5.13 2958.4 - 691340 - - - 2.1422 - 2.917 0.501 - 213.7 1 2 0 0.0045 19 0 0 0 5.19E+05 2.28E+07 - - - 3.9476 0.9993 221125_WJC_METTL3_EV_vs_WT_F07.17805.17805.4 0.000318 16/114 R.K[136.11]R[166.11]EEAAAVPAAAPDDLALLK[136.11].N "sp|Q86UE4|LYRIC_HUMAN,tr|E5RJU9|E5RJU9_HUMAN" 2 2074.1633 1.2 104100 17805 4 2074.168551 519.5481 Protein LYRIC OS=Homo sapiens OX=9606 GN=MTDH PE=1 SV=2 4.78 2958.7 - 264341 - - - 2.5437 - 2.489 0.441 - 115.8 1 2 1 0.0053 20 0 0 0 2.60E+07 2.17E+07 - - - 3.3679 0.9984 221125_WJC_METTL3_EV_vs_WT_F07.17806.17806.4 0.00264 17/114 R.KREEAAAVPAAAPDDLALLK.N "sp|Q86UE4|LYRIC_HUMAN,tr|E5RJU9|E5RJU9_HUMAN" 2 2048.1266 1.2 104101 17806 4 2048.133399 513.0389 Protein LYRIC OS=Homo sapiens OX=9606 GN=MTDH PE=1 SV=2 4.78 2958.9 - 194256 - - - 3.3172 - 3.475 0.408 - 253.3 1 2 1 0.0068 20 0 0 0 2.60E+07 2.17E+07 - - - 3.1918 1 221125_WJC_METTL3_EV_vs_WT_F07.17814.17814.4 4.35E-10 18/114 R.VHLDIQVGEHANDYAEIAAK.D sp|Q9BVK6|TMED9_HUMAN 1 2192.0862 1.86 104107 17814 4 2192.094713 549.0288 Transmembrane emp24 domain-containing protein 9 OS=Homo sapiens OX=9606 GN=TMED9 PE=1 SV=2 4.72 2959.8 - 1.20E+06 - - - 3.8853 - 3.507 0.641 - 268 1 2 0 0.0085 20 0 0 0 2.16E+07 1.16E+07 - - - 5.2224 0.9999 221125_WJC_METTL3_EV_vs_WT_F07.17816.17816.3 1.17E-09 19/84 K.DKGGINLTATC[160.03]PQSELDAETVK.S sp|Q9Y295|DRG1_HUMAN 1 2346.1373 0.39 104109 17816 3 2346.141371 783.053 Developmentally-regulated GTP-binding protein 1 OS=Homo sapiens OX=9606 GN=DRG1 PE=1 SV=1 4.32 2960.1 - 616437 - - - 1.7326 - 3.372 0.564 - 421.2 1 2 1 0.0041 22 0 0 0 7.44E+06 1.89E+07 - - - 7.7087 0.9858 221125_WJC_METTL3_EV_vs_WT_F07.17820.17820.3 0.000607 Oct-40 G.IHLLDPDVVAR[166.11].F sp|Q86U44|MTA70_HUMAN 1 1256.7116 0.04 104113 17820 3 1256.713483 419.9112 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 5.21 2960.6 - 153481 - - - 1.4657 - 1.943 0.43 - 239.4 1 1 0 0.0018 11 0 0 0 1.55E+05 3.94E+06 - - - 5.2205 1 221125_WJC_METTL3_EV_vs_WT_F07.17823.17823.3 2.25E-10 20/76 R.QQVAFYGQTLGQAQAHSQEQ.- sp|Q96I24|FUBP3_HUMAN 1 2218.0403 - 104115 17823 3 2218.045411 740.354 Far upstream element-binding protein 3 OS=Homo sapiens OX=9606 GN=FUBP3 PE=1 SV=2 5.24 2961.1 - 929332 - - - 2.3002 - 3.282 0.546 - 445.9 1 2 0 0.0051 20 0 0 0 - - - - - 7.5092 0.9998 221125_WJC_METTL3_EV_vs_WT_F07.17825.17825.4 2.29E-11 22/108 K.FKDDVMPATYC[160.03]EIDLDKEK.R "sp|Q9HD45|TM9S3_HUMAN,tr|Q5TB53|Q5TB53_HUMAN" 2 2316.0654 1.11 104116 17825 4 2316.072076 580.0236 Transmembrane 9 superfamily member 3 OS=Homo sapiens OX=9606 GN=TM9SF3 PE=1 SV=2 4.23 2961.3 - 822499 - - - 2.8885 - 3.912 0.583 - 535.1 1 2 2 0.0067 19 0 0 0 6.94E+06 6.23E+06 - - - 4.76 0.9999 221125_WJC_METTL3_EV_vs_WT_F07.17826.17826.3 2.71E-08 24/76 R.K[136.11]R[166.11]EEAAAVPAAAPDDLALLK[136.11].N "sp|Q86UE4|LYRIC_HUMAN,tr|E5RJU9|E5RJU9_HUMAN" 2 2074.1633 1.11 104117 17826 3 2074.166238 692.395 Protein LYRIC OS=Homo sapiens OX=9606 GN=MTDH PE=1 SV=2 4.78 2961.4 - 574304 - - - 1.4285 - 3.676 0.565 - 760.4 1 2 1 0.003 20 0 0 0 1.57E+07 1.42E+07 - - - 7.9966 1 221125_WJC_METTL3_EV_vs_WT_F07.17827.17827.3 9.55E-08 24/76 R.KREEAAAVPAAAPDDLALLK.N "sp|Q86UE4|LYRIC_HUMAN,tr|E5RJU9|E5RJU9_HUMAN" 2 2048.1266 1.1 104118 17827 3 2048.131358 683.7161 Protein LYRIC OS=Homo sapiens OX=9606 GN=MTDH PE=1 SV=2 4.78 2961.6 - 686172 - - - 2.3207 - 4.03 0.59 - 720.4 1 2 1 0.0048 20 0 0 0 1.56E+07 1.42E+07 - - - 8.4979 1 221125_WJC_METTL3_EV_vs_WT_F07.17828.17828.3 5.73E-12 22/76 R.VHLDIQVGEHANDYAEIAAK[136.11].D sp|Q9BVK6|TMED9_HUMAN 1 2200.1004 2.11 104119 17828 3 2200.102336 734.3741 Transmembrane emp24 domain-containing protein 9 OS=Homo sapiens OX=9606 GN=TMED9 PE=1 SV=2 4.72 2961.7 - 481774 - - - 0.8818 - 4.428 0.662 - 400 1 2 0 0.0019 20 0 0 0 8.82E+06 4.18E+06 - - - 9.5299 0.999 221125_WJC_METTL3_EV_vs_WT_F07.17829.17829.4 0.00102 12/120 K.AIGSK[136.11]DDGK[136.11]LDLSVVENGGLK[136.11].A "sp|Q99986|VRK1_HUMAN,tr|A0A7P0T838|A0A7P0T838_HUMAN,tr|H0YJJ9|H0YJJ9_HUMAN,tr|A0A7P0TA16|A0A7P0TA16_HUMAN,tr|A0A7P0T8N0|A0A7P0T8N0_HUMAN,tr|H0YJF7|H0YJF7_HUMAN,tr|A0A7P0T9T1|A0A7P0T9T1_HUMAN,tr|A0A7P0Z4A4|A0A7P0Z4A4_HUMAN,tr|A0A7P0Z445|A0A7P0Z445_HUMAN,tr|A0A7P0TAA6|A0A7P0TAA6_HUMAN,tr|A0A7P0T9E5|A0A7P0T9E5_HUMAN,tr|A0A7P0TBB8|A0A7P0TBB8_HUMAN,tr|A0A7P0Z462|A0A7P0Z462_HUMAN,tr|A0A7P0TBE4|A0A7P0TBE4_HUMAN,tr|A0A7P0T925|A0A7P0T925_HUMAN,tr|H0YJ50|H0YJ50_HUMAN,tr|A0A7P0TA65|A0A7P0TA65_HUMAN,tr|A0A7P0T824|A0A7P0T824_HUMAN,tr|A0A7P0T9I1|A0A7P0T9I1_HUMAN,tr|A0A7P0T977|A0A7P0T977_HUMAN,tr|A0A7P0Z3Z7|A0A7P0Z3Z7_HUMAN,tr|A0A7P0TAS8|A0A7P0TAS8_HUMAN,tr|A0A7P0TB15|A0A7P0TB15_HUMAN,tr|A0A7P0T952|A0A7P0T952_HUMAN" 24 2138.1645 0.46 104120 17829 4 2138.166681 535.5484 Serine\threonine-protein kinase VRK1 OS=Homo sapiens OX=9606 GN=VRK1 PE=1 SV=1 4.68 2961.8 - 321394 - - - 1.014 - 1.591 0.379 - 59.3 1 2 2 0.0022 21 0 0 0 9.42E+05 2.03E+06 - - - 2.6778 0.9695 221125_WJC_METTL3_EV_vs_WT_F07.17831.17831.3 1.98E-07 14/84 K.SKAEAESLYQSKYEELQITAGR.H sp|P04264|K2C1_HUMAN 1 2500.2445 0.1 104122 17831 3 2501.23907 834.4221 "Keratin, type II cytoskeletal 1 OS=Homo sapiens OX=9606 GN=KRT1 PE=1 SV=6" 4.94 2962.1 - 258674 - - - 397.7699 - 2.74 0.487 - 213.5 1 2 2 0.9945 22 0 0 0 6.39E+05 6.44E+06 - - - 6.0838 0.9998 221125_WJC_METTL3_EV_vs_WT_F07.17835.17835.4 2.40E-06 14/78 K.YKDDPVDLRLDIER.R "sp|Q9Y2W1|TR150_HUMAN,tr|A0A3B3ITZ9|A0A3B3ITZ9_HUMAN" 2 1745.8948 2.43 104126 17835 4 1745.897155 437.481 Thyroid hormone receptor-associated protein 3 OS=Homo sapiens OX=9606 GN=THRAP3 PE=1 SV=2 4.36 2962.6 - 194756 - - - 1.3409 - 2.68 0.489 - 172.6 1 2 2 0.0023 14 0 0 0 3.78E+06 1.56E+06 - - - 3.8404 1 221125_WJC_METTL3_EV_vs_WT_F07.17839.17839.3 2.48E-06 14/60 K.STTSDIPHMLNQVESK.V "sp|Q52LJ0|FA98B_HUMAN,tr|H0YNA1|H0YNA1_HUMAN" 2 1785.8567 1.14 104129 17839 3 1785.860282 596.2928 Protein FAM98B OS=Homo sapiens OX=9606 GN=FAM98B PE=1 SV=2 5.3 2963.1 - 3.10E+06 - - - 1.9979 - 2.846 0.567 - 280.9 1 2 0 0.0036 16 0 0 0 2.72E+07 2.39E+07 - - - 7.5442 0.9999 221125_WJC_METTL3_EV_vs_WT_F07.17840.17840.3 4.36E-05 18/52 K.HWPFQVINDGDK[136.11]PK[136.11].V "sp|P0DMV8|HS71A_HUMAN,sp|P0DMV9|HS71B_HUMAN,tr|A0A0G2JIW1|A0A0G2JIW1_HUMAN" 3 1695.8704 0.13 104130 17840 3 1695.876394 566.2974 Heat shock 70 kDa protein 1A OS=Homo sapiens OX=9606 GN=HSPA1A PE=1 SV=1 6.75 2963.2 - 1.06E+06 - - - 3.5404 - 3.262 0.563 - 653.5 1 2 0 0.006 14 0 0 0 3.32E+06 2.64E+07 - - - 7.9573 1 221125_WJC_METTL3_EV_vs_WT_F07.17843.17843.3 4.85E-12 22/68 K.R[166.11]GAPPSSNIEDFHGLLPK[136.11].G "sp|P43243|MATR3_HUMAN,tr|A8MXP9|A8MXP9_HUMAN,tr|D6R991|D6R991_HUMAN,tr|A0A0R4J2E8|A0A0R4J2E8_HUMAN,tr|H0Y8T4|H0Y8T4_HUMAN,tr|D6REM6|D6REM6_HUMAN" 6 1952.0235 1.38 104133 17843 3 1952.026529 651.6818 Matrin-3 OS=Homo sapiens OX=9606 GN=MATR3 PE=1 SV=2 6.75 2963.5 - 644407 - - - 1.562 - 4.067 0.675 - 576.4 1 2 0 0.003 18 0 0 0 5.30E+08 3.85E+08 - - - 9.5581 1 221125_WJC_METTL3_EV_vs_WT_F07.17846.17846.4 1.78E-08 14/78 K.HWPFQVINDGDK[136.11]PK[136.11].V "sp|P0DMV8|HS71A_HUMAN,sp|P0DMV9|HS71B_HUMAN,tr|A0A0G2JIW1|A0A0G2JIW1_HUMAN" 3 1695.8704 0.16 104136 17846 4 1695.871144 424.9749 Heat shock 70 kDa protein 1A OS=Homo sapiens OX=9606 GN=HSPA1A PE=1 SV=1 6.75 2963.8 - 214378 - - - 0.4446 - 2.615 0.558 - 132.9 1 2 0 0.0008 14 0 0 0 4.98E+05 3.10E+06 - - - 4.4325 0.9986 221125_WJC_METTL3_EV_vs_WT_F07.17848.17848.4 2.88E-07 16/96 R.GGSPFAIVITQQHQIHR.S sp|Q9HCD5|NCOA5_HUMAN 1 1888.0068 1.62 104138 17848 4 1888.016139 473.009 Nuclear receptor coactivator 5 OS=Homo sapiens OX=9606 GN=NCOA5 PE=1 SV=2 9.76 2964.1 - 155144 - - - 4.9656 - 3.133 0.408 - 249.8 1 2 0 0.0094 17 0 0 0 1.07E+07 6.59E+06 - - - 3.1711 1 221125_WJC_METTL3_EV_vs_WT_F07.17850.17850.4 6.00E-08 20/102 K.R[166.11]GAPPSSNIEDFHGLLPK[136.11].G "sp|P43243|MATR3_HUMAN,tr|A8MXP9|A8MXP9_HUMAN,tr|D6R991|D6R991_HUMAN,tr|A0A0R4J2E8|A0A0R4J2E8_HUMAN,tr|H0Y8T4|H0Y8T4_HUMAN,tr|D6REM6|D6REM6_HUMAN" 6 1952.0235 1.47 104139 17850 4 1952.027947 489.0131 Matrin-3 OS=Homo sapiens OX=9606 GN=MATR3 PE=1 SV=2 6.75 2964.3 - 1.08E+06 - - - 2.2884 - 3.572 0.547 - 221.4 1 2 0 0.0045 18 0 0 0 8.27E+08 5.64E+08 - - - 4.422 0.9471 221125_WJC_METTL3_EV_vs_WT_F07.17852.17852.4 0.000314 12/108 K.FK[136.11]DDVMPATYC[160.03]EIDLDK[136.11]EK[136.11].R "sp|Q9HD45|TM9S3_HUMAN,tr|Q5TB53|Q5TB53_HUMAN" 2 2340.108 1.65 104140 17852 4 2340.104976 586.0343 Transmembrane 9 superfamily member 3 OS=Homo sapiens OX=9606 GN=TM9SF3 PE=1 SV=2 4.23 2964.6 - 480348 - - - -1.2863 - 2.409 0.176 - 47.1 1 2 2 -0.003 19 0 0 0 1.03E+07 6.23E+06 - - - 1.0545 0.9988 221125_WJC_METTL3_EV_vs_WT_F07.17854.17854.3 0.000105 13/84 R.VSSPLPSPSAMTDAANSQAAAK.L "sp|Q8WXI9|P66B_HUMAN,tr|A0A0U1RRM1|A0A0U1RRM1_HUMAN,tr|A0A0U1RR30|A0A0U1RR30_HUMAN" 3 2100.0157 1.91 104142 17854 3 2100.024007 701.0125 Transcriptional repressor p66-beta OS=Homo sapiens OX=9606 GN=GATAD2B PE=1 SV=1 5.81 2964.8 - 268785 - - - 3.9395 - 2.389 0.373 - 74.1 1 2 0 0.0083 22 0 0 0 1.18E+07 6.17E+06 - - - 4.761 0.9993 221125_WJC_METTL3_EV_vs_WT_F07.17856.17856.2 0.000833 30-Aug K.STTSDIPHMLNQVESK.V "sp|Q52LJ0|FA98B_HUMAN,tr|H0YNA1|H0YNA1_HUMAN" 2 1785.8567 1.95 104144 17856 2 1785.854048 893.9356 Protein FAM98B OS=Homo sapiens OX=9606 GN=FAM98B PE=1 SV=2 5.3 2965.1 - 122664 - - - -1.4928 - 1.524 0.419 - 134.6 1 2 0 -0.0027 16 0 0 0 2.60E+06 1.33E+06 - - - 3.1708 0.9998 221125_WJC_METTL3_EV_vs_WT_F07.17866.17866.4 4.06E-08 14/102 K.THPSVVPGSIAFSLPQRK.W "sp|P46459|NSF_HUMAN,tr|I3L0L3|I3L0L3_HUMAN,tr|I3L0N3|I3L0N3_HUMAN" 3 1920.0581 0.41 104152 17866 4 1920.064896 481.0218 Vesicle-fusing ATPase OS=Homo sapiens OX=9606 GN=NSF PE=1 SV=3 11 2966.4 - 326817 - - - 3.5233 - 2.747 0.486 - 121.8 1 2 0 0.0068 18 0 0 0 4.65E+06 1.13E+07 - - - 3.8004 1 221125_WJC_METTL3_EV_vs_WT_F07.17874.17874.3 2.24E-12 32/68 K.RPLDDGVGNQLGALVHQR.T sp|Q96I24|FUBP3_HUMAN 1 1944.029 1.87 104158 17874 3 1944.032523 649.0169 Far upstream element-binding protein 3 OS=Homo sapiens OX=9606 GN=FUBP3 PE=1 SV=2 6.75 2967.4 - 3.82E+06 - - - 1.8348 - 5.985 0.622 - 1377.3 1 2 0 0.0036 18 0 0 0 2.61E+09 1.40E+09 - - - 9.9291 0.9999 221125_WJC_METTL3_EV_vs_WT_F07.17876.17876.3 1.61E-07 21/68 K.KQGGLGPMNIPLVSDPKR.T "sp|Q06830|PRDX1_HUMAN,tr|A0A0A0MSI0|A0A0A0MSI0_HUMAN" 2 1906.0459 0.79 104160 17876 3 1906.053347 636.3559 Peroxiredoxin-1 OS=Homo sapiens OX=9606 GN=PRDX1 PE=1 SV=1 9.99 2967.6 - 995643 - - - 3.9322 - 3.348 0.545 - 493.1 1 2 0 0.0075 18 0 0 0 2.01E+07 2.55E+07 - - - 7.6231 1 221125_WJC_METTL3_EV_vs_WT_F07.17883.17883.3 0.000695 24/68 K.R[166.11]PLDDGVGNQLGALVHQR[166.11].T sp|Q96I24|FUBP3_HUMAN 1 1964.0455 1.87 104165 17883 3 1964.047051 655.6891 Far upstream element-binding protein 3 OS=Homo sapiens OX=9606 GN=FUBP3 PE=1 SV=2 6.75 2968.6 - 4.75E+06 - - - 0.7917 - 3.688 0.571 - 723.6 1 2 0 0.0016 18 0 0 0 2.61E+09 1.40E+09 - - - 8.1554 1 221125_WJC_METTL3_EV_vs_WT_F07.17887.17887.4 1.68E-09 22/138 R.QTIINDYITSQQMHHNAATAMAQR.A "sp|Q9Y618|NCOR2_HUMAN,tr|C9J7T7|C9J7T7_HUMAN,tr|C9JE98|C9JE98_HUMAN,tr|H7C1J7|H7C1J7_HUMAN,tr|C9J0Q5|C9J0Q5_HUMAN,tr|A0A384DVL6|A0A384DVL6_HUMAN" 6 2742.2966 2.46 104169 17887 4 2742.30242 686.5814 Nuclear receptor corepressor 2 OS=Homo sapiens OX=9606 GN=NCOR2 PE=1 SV=3 6.92 2969 - 366798 - - - 2.1161 - 3.546 0.589 - 320.4 1 2 0 0.0058 24 0 0 0 1.47E+07 5.98E+06 - - - 4.7573 0.9998 221125_WJC_METTL3_EV_vs_WT_F07.17892.17892.4 3.88E-06 15/102 K.RGAPPSSNIEDFHGLLPK.G "sp|P43243|MATR3_HUMAN,tr|A8MXP9|A8MXP9_HUMAN,tr|D6R991|D6R991_HUMAN,tr|A0A0R4J2E8|A0A0R4J2E8_HUMAN,tr|H0Y8T4|H0Y8T4_HUMAN,tr|D6REM6|D6REM6_HUMAN" 6 1934.001 1.45 104172 17892 4 1934.008069 484.5075 Matrin-3 OS=Homo sapiens OX=9606 GN=MATR3 PE=1 SV=2 6.75 2969.7 - 4.50E+06 - - - 3.6499 - 2.413 0.476 - 108.2 1 2 0 0.0071 18 0 0 0 7.44E+08 5.14E+08 - - - 3.6689 1 221125_WJC_METTL3_EV_vs_WT_F07.17896.17896.3 2.68E-10 15/64 R.NGSDC[160.03]PDKFC[160.03]LFQSETK.N "sp|P02788|TRFL_HUMAN,tr|E7EQB2|E7EQB2_HUMAN,tr|E7ER44|E7ER44_HUMAN" 3 2031.8666 999 104176 17896 3 2031.867342 678.2962 Lactotransferrin OS=Homo sapiens OX=9606 GN=LTF PE=1 SV=6 4.56 2970.1 - 335517 - - - 0.3519 - 3.102 0.642 - 413.4 1 2 1 0.0007 17 0 0 0 7.59E+06 0.00E+00 - - - 8.5574 0.9759 221125_WJC_METTL3_EV_vs_WT_F07.17903.17903.2 4.72E-06 20-Dec V.GNQLGALVHQR[166.11].T sp|Q96I24|FUBP3_HUMAN 1 1201.6555 1.81 104181 17903 2 1201.659006 601.835 Far upstream element-binding protein 3 OS=Homo sapiens OX=9606 GN=FUBP3 PE=1 SV=2 9.76 2971.1 - 508185 - - - 2.8985 - 2.497 0.514 - 573.4 1 1 0 0.0035 11 0 0 0 1.37E+08 7.56E+07 - - - 5.3118 0.9999 221125_WJC_METTL3_EV_vs_WT_F07.17905.17905.3 0.000597 19/72 R.GGRPNEIEPPPPEMPPWQK.R "sp|Q8NCA5|FA98A_HUMAN,sp|Q52LJ0|FA98B_HUMAN" 2 2155.0521 1.69 104183 17905 3 2155.04399 719.358 Protein FAM98A OS=Homo sapiens OX=9606 GN=FAM98A PE=1 SV=2 4.79 2971.4 - 375536 - - - -3.7442 - 3.644 0.509 - 418.7 1 2 0 -0.0081 19 0 0 0 7.05E+06 4.18E+06 - - - 7.3895 1 221125_WJC_METTL3_EV_vs_WT_F07.17909.17909.4 2.90E-10 26/108 R.HALDAHQQSIPAVLEIPSK.E sp|Q16864|VATF_HUMAN 1 2053.0956 2.1 104185 17909 4 2053.096916 514.2812 V-type proton ATPase subunit F OS=Homo sapiens OX=9606 GN=ATP6V1F PE=1 SV=2 5.99 2971.9 - 951351 - - - 0.622 - 4.344 0.646 - 509.6 1 2 0 0.0013 19 0 0 0 3.28E+07 1.57E+07 - - - 5.3453 1 221125_WJC_METTL3_EV_vs_WT_F07.17911.17911.4 1.26E-05 15/138 R.QTIINDYITSQQMHHNAATAMAQR[166.11].A "sp|Q9Y618|NCOR2_HUMAN,tr|C9J7T7|C9J7T7_HUMAN,tr|C9JE98|C9JE98_HUMAN,tr|H7C1J7|H7C1J7_HUMAN,tr|C9J0Q5|C9J0Q5_HUMAN,tr|A0A384DVL6|A0A384DVL6_HUMAN" 6 2752.3049 2.46 104187 17911 4 2752.306889 689.0835 Nuclear receptor corepressor 2 OS=Homo sapiens OX=9606 GN=NCOR2 PE=1 SV=3 6.92 2972.1 - 519088 - - - 0.7274 - 3.15 0.491 - 112.1 1 2 0 0.002 24 0 0 0 1.47E+07 5.98E+06 - - - 3.8674 0.8359 221125_WJC_METTL3_EV_vs_WT_F07.17914.17914.2 0.352 12-Jul L.GALVHQR.T sp|Q96I24|FUBP3_HUMAN 1 779.4402 1.9 104190 17914 2 779.439622 390.7274 Far upstream element-binding protein 3 OS=Homo sapiens OX=9606 GN=FUBP3 PE=1 SV=2 9.76 2972.5 - 253583 - - - -0.7685 - 1.473 0.165 - 229.4 1 1 0 -0.0006 7 0 0 0 3.17E+07 1.67E+07 - - - 1.4867 0.9195 221125_WJC_METTL3_EV_vs_WT_F07.17915.17915.2 0.234 14-Aug Q.LGALVHQR[166.11].T sp|Q96I24|FUBP3_HUMAN 1 902.5326 1.85 104191 17915 2 902.532632 452.2736 Far upstream element-binding protein 3 OS=Homo sapiens OX=9606 GN=FUBP3 PE=1 SV=2 9.76 2972.7 - 194139 - - - 0.0853 - 1.852 0.156 - 226.1 1 1 0 0.0001 8 0 0 0 3.48E+07 1.88E+07 - - - 2.0518 0.9997 221125_WJC_METTL3_EV_vs_WT_F07.17918.17918.4 0.000159 17/102 R.LSLNNGSITHLVIR[166.11]PNGR[166.11].V "sp|Q96HS1|PGAM5_HUMAN,tr|F5GXG4|F5GXG4_HUMAN" 2 1980.1132 1.01 104192 17918 4 1980.109394 496.0356 "Serine\threonine-protein phosphatase PGAM5, mitochondrial OS=Homo sapiens OX=9606 GN=PGAM5 PE=1 SV=2" 12 2973.1 - 730601 - - - -1.913 - 3.028 0.37 - 222.1 1 2 0 -0.0038 18 0 0 0 3.64E+07 3.60E+07 - - - 2.8249 1 221125_WJC_METTL3_EV_vs_WT_F07.17920.17920.3 1.73E-08 14/88 R.ASTASPC[160.03]NNNINAATAVALQEPR.K sp|Q71RC2|LARP4_HUMAN 1 2369.1394 1.7 104194 17920 3 2369.135301 790.7204 La-related protein 4 OS=Homo sapiens OX=9606 GN=LARP4 PE=1 SV=3 6.04 2973.3 - 459881 - - - -1.7179 - 3.079 0.595 - 82.6 1 2 0 -0.0041 23 0 0 0 8.23E+07 4.84E+07 - - - 7.8108 0.8604 221125_WJC_METTL3_EV_vs_WT_F07.17924.17924.2 0.901 12-Jul L.GALVHQR[166.11].T sp|Q96I24|FUBP3_HUMAN 1 789.4485 1.9 104198 17924 2 789.448245 395.7315 Far upstream element-binding protein 3 OS=Homo sapiens OX=9606 GN=FUBP3 PE=1 SV=2 9.76 2973.8 - 176466 - - - -0.3116 - 1.507 0.165 - 224.9 1 1 0 -0.0002 7 0 0 0 3.17E+07 1.67E+07 - - - 1.5591 1 221125_WJC_METTL3_EV_vs_WT_F07.17928.17928.4 7.95E-06 21/102 K.KQGGLGPMNIPLVSDPKR.T "sp|Q06830|PRDX1_HUMAN,tr|A0A0A0MSI0|A0A0A0MSI0_HUMAN" 2 1906.0459 0.64 104200 17928 4 1906.048324 477.5187 Peroxiredoxin-1 OS=Homo sapiens OX=9606 GN=PRDX1 PE=1 SV=1 9.99 2974.3 - 800291 - - - 1.2969 - 3.323 0.504 - 402.1 1 2 0 0.0025 18 0 0 0 4.68E+07 7.29E+07 - - - 4.0235 0.9999 221125_WJC_METTL3_EV_vs_WT_F07.17930.17930.4 1.29E-06 18/108 R.HALDAHQQSIPAVLEIPSK[136.11].E sp|Q16864|VATF_HUMAN 1 2061.1098 2.09 104202 17930 4 2061.107305 516.2847 V-type proton ATPase subunit F OS=Homo sapiens OX=9606 GN=ATP6V1F PE=1 SV=2 5.99 2974.6 - 617363 - - - -1.2294 - 2.599 0.458 - 187.7 1 2 0 -0.0025 19 0 0 0 3.27E+07 1.56E+07 - - - 3.5348 0.9614 221125_WJC_METTL3_EV_vs_WT_F07.17931.17931.2 0.301 14-Oct Q.LGALVHQR.T sp|Q96I24|FUBP3_HUMAN 1 892.5243 1.85 104203 17931 2 892.524588 447.2694 Far upstream element-binding protein 3 OS=Homo sapiens OX=9606 GN=FUBP3 PE=1 SV=2 9.76 2974.7 - 389991 - - - 0.3395 - 2.129 0.198 - 436.3 1 1 0 0.0003 8 0 0 0 3.48E+07 1.88E+07 - - - 2.7823 0.9996 221125_WJC_METTL3_EV_vs_WT_F07.17932.17932.2 0.00304 Aug-34 K.RPLDDGVGNQLGALVHQR.T sp|Q96I24|FUBP3_HUMAN 1 1944.029 2.89 104204 17932 2 1944.030676 973.0218 Far upstream element-binding protein 3 OS=Homo sapiens OX=9606 GN=FUBP3 PE=1 SV=2 6.75 2974.8 - 218852 - - - 0.8848 - 1.792 0.411 - 55 1 2 0 0.0017 18 0 0 0 2.20E+07 7.61E+06 - - - 3.5103 1 221125_WJC_METTL3_EV_vs_WT_F07.17934.17934.3 5.13E-14 27/68 K.RGAPPSSNIEDFHGLLPK.G "sp|P43243|MATR3_HUMAN,tr|A8MXP9|A8MXP9_HUMAN,tr|D6R991|D6R991_HUMAN,tr|A0A0R4J2E8|A0A0R4J2E8_HUMAN,tr|H0Y8T4|H0Y8T4_HUMAN,tr|D6REM6|D6REM6_HUMAN" 6 1934.001 1.35 104205 17934 3 1934.001828 645.6743 Matrin-3 OS=Homo sapiens OX=9606 GN=MATR3 PE=1 SV=2 6.75 2975 - 4.23E+06 - - - 0.423 - 4.906 0.7 - 1048.7 1 2 0 0.0008 18 0 0 0 4.77E+08 3.53E+08 - - - 10.3045 0.9907 221125_WJC_METTL3_EV_vs_WT_F07.17936.17936.2 5.66E-06 13/20 V.GNQLGALVHQR.T sp|Q96I24|FUBP3_HUMAN 1 1191.6473 1.82 104206 17936 2 1191.647586 596.8309 Far upstream element-binding protein 3 OS=Homo sapiens OX=9606 GN=FUBP3 PE=1 SV=2 9.76 2975.3 - 1.97E+06 - - - 0.2794 - 2.432 0.411 - 649.3 1 1 0 0.0003 11 0 0 0 1.37E+08 7.54E+07 - - - 4.4807 0.9988 221125_WJC_METTL3_EV_vs_WT_F07.17937.17937.3 3.82E-07 21/88 R.ASTASPC[160.03]NNNINAATAVALQEPR[166.11].K sp|Q71RC2|LARP4_HUMAN 1 2379.1476 1.72 104207 17937 3 2380.144303 794.0565 La-related protein 4 OS=Homo sapiens OX=9606 GN=LARP4 PE=1 SV=3 6.04 2975.4 - 812288 - - - 418.9156 - 3.517 0.593 - 518.6 1 2 0 0.9967 23 0 0 0 8.22E+07 4.78E+07 - - - 7.8256 1 221125_WJC_METTL3_EV_vs_WT_F07.17938.17938.3 5.57E-14 16/112 R.SAGLAPDC[160.03]EASATAETTVSSVGTC[160.03]EAAGK[136.11].S sp|Q9NQE9|HINT3_HUMAN 1 2805.2524 0.51 104208 17938 3 2805.251707 936.0914 Adenosine 5'-monophosphoramidase HINT3 OS=Homo sapiens OX=9606 GN=HINT3 PE=1 SV=1 4 2975.5 - 658795 - - - -0.2538 - 3.708 0.73 - 231.6 1 2 0 -0.0007 29 0 0 0 7.09E+06 1.39E+07 - - - 9.6935 0.9999 221125_WJC_METTL3_EV_vs_WT_F07.17939.17939.4 0.000511 16/96 K.HTGFLEISQHSQEFINR.L sp|Q7L0Y3|TM10C_HUMAN 1 2041.997 0.73 104209 17939 4 2041.998632 511.5065 tRNA methyltransferase 10 homolog C OS=Homo sapiens OX=9606 GN=TRMT10C PE=1 SV=2 6 2975.6 - 513171 - - - 0.8056 - 2.801 0.407 - 203.8 1 2 0 0.0016 17 0 0 0 1.58E+07 2.15E+07 - - - 3.1257 1 221125_WJC_METTL3_EV_vs_WT_F07.17940.17940.3 8.48E-09 14/88 R.VVSSEGGR[166.11]PSVDLSFQPSQPLSK[136.11].S "sp|P49815|TSC2_HUMAN,tr|H3BQK4|H3BQK4_HUMAN,tr|A0A2R8Y7C8|A0A2R8Y7C8_HUMAN,tr|A0A2R8YDR3|A0A2R8YDR3_HUMAN,tr|A0A2R8Y7X5|A0A2R8Y7X5_HUMAN,tr|A0A2R8YDZ2|A0A2R8YDZ2_HUMAN,tr|A0A2R8YGD6|A0A2R8YGD6_HUMAN,tr|X5D2U8|X5D2U8_HUMAN,tr|A0A2R8Y5F1|A0A2R8Y5F1_HUMAN,tr|A0A2R8YGU4|A0A2R8YGU4_HUMAN,tr|A0A2R8Y670|A0A2R8Y670_HUMAN,tr|H3BMQ0|H3BMQ0_HUMAN,tr|A0A2R8Y6C9|A0A2R8Y6C9_HUMAN" 13 2418.251 1.46 104210 17940 3 2418.252298 807.0909 Tuberin OS=Homo sapiens OX=9606 GN=TSC2 PE=1 SV=2 6.04 2975.8 - 458327 - - - 0.5475 - 2.626 0.65 - 134.9 1 2 0 0.0013 23 0 0 0 1.28E+07 8.72E+06 - - - 8.0514 0.9999 221125_WJC_METTL3_EV_vs_WT_F07.17941.17941.3 4.18E-09 16/88 R.VVSSEGGRPSVDLSFQPSQPLSK.S "sp|P49815|TSC2_HUMAN,tr|H3BQK4|H3BQK4_HUMAN,tr|A0A2R8Y7C8|A0A2R8Y7C8_HUMAN,tr|A0A2R8YDR3|A0A2R8YDR3_HUMAN,tr|A0A2R8Y7X5|A0A2R8Y7X5_HUMAN,tr|A0A2R8YDZ2|A0A2R8YDZ2_HUMAN,tr|A0A2R8YGD6|A0A2R8YGD6_HUMAN,tr|X5D2U8|X5D2U8_HUMAN,tr|A0A2R8Y5F1|A0A2R8Y5F1_HUMAN,tr|A0A2R8YGU4|A0A2R8YGU4_HUMAN,tr|A0A2R8Y670|A0A2R8Y670_HUMAN,tr|H3BMQ0|H3BMQ0_HUMAN,tr|A0A2R8Y6C9|A0A2R8Y6C9_HUMAN" 13 2400.2285 1.46 104211 17941 3 2400.238858 801.0834 Tuberin OS=Homo sapiens OX=9606 GN=TSC2 PE=1 SV=2 6.04 2975.9 - 421962 - - - 4.3138 - 2.714 0.612 - 160.8 1 2 0 0.0104 23 0 0 0 1.28E+07 8.72E+06 - - - 7.7026 0.9999 221125_WJC_METTL3_EV_vs_WT_F07.17942.17942.3 1.32E-09 16/60 K.EESSSISSLK[136.11]DEFTQR[166.11].L "sp|P82094|TMF1_HUMAN,tr|F8WF45|F8WF45_HUMAN,tr|A0A2R8Y7M0|A0A2R8Y7M0_HUMAN" 3 1859.8868 1.74 104212 17942 3 1859.888832 620.9695 TATA element modulatory factor OS=Homo sapiens OX=9606 GN=TMF1 PE=1 SV=2 4.41 2976 - 376150 - - - 1.1081 - 3.281 0.579 - 382.8 1 2 1 0.0021 16 0 0 0 2.67E+07 1.53E+07 - - - 8.0433 1 221125_WJC_METTL3_EV_vs_WT_F07.17943.17943.3 5.26E-11 18/112 R.SAGLAPDC[160.03]EASATAETTVSSVGTC[160.03]EAAGK.S sp|Q9NQE9|HINT3_HUMAN 1 2797.2382 0.51 104213 17943 3 2797.243422 933.42 Adenosine 5'-monophosphoramidase HINT3 OS=Homo sapiens OX=9606 GN=HINT3 PE=1 SV=1 4 2976.1 - 324512 - - - 1.86 - 3.122 0.725 - 186.4 1 2 0 0.0052 29 0 0 0 7.09E+06 1.39E+07 - - - 9.2408 1 221125_WJC_METTL3_EV_vs_WT_F07.17945.17945.2 7.29E-08 15/28 K.NQVALNPQNTVFDAK[136.11].R "sp|P0DMV8|HS71A_HUMAN,sp|P0DMV9|HS71B_HUMAN,tr|A0A0G2JIW1|A0A0G2JIW1_HUMAN" 3 1665.8566 0.09 104215 17945 2 1665.852305 833.9356 Heat shock 70 kDa protein 1A OS=Homo sapiens OX=9606 GN=HSPA1A PE=1 SV=1 5.84 2976.4 - 140669 - - - -2.5686 - 2.8 0.628 - 650.4 1 2 0 -0.0043 15 0 0 0 5.77E+06 6.22E+07 - - - 6.2094 1 221125_WJC_METTL3_EV_vs_WT_F07.17950.17950.3 8.20E-08 23/64 K.HTGFLEISQHSQEFINR.L sp|Q7L0Y3|TM10C_HUMAN 1 2041.997 0.91 104218 17950 3 2041.995309 681.6729 tRNA methyltransferase 10 homolog C OS=Homo sapiens OX=9606 GN=TRMT10C PE=1 SV=2 6 2977 - 738369 - - - -0.8217 - 4.54 0.614 - 774.8 1 2 0 -0.0017 17 0 0 0 1.99E+07 2.18E+07 - - - 9.2071 1 221125_WJC_METTL3_EV_vs_WT_F07.17952.17952.4 0.000191 15/96 K.HTGFLEISQHSQEFINR[166.11].L sp|Q7L0Y3|TM10C_HUMAN 1 2052.0053 0.74 104220 17952 4 2052.003763 514.0086 tRNA methyltransferase 10 homolog C OS=Homo sapiens OX=9606 GN=TRMT10C PE=1 SV=2 6 2977.1 - 1.18E+06 - - - -0.7281 - 3.242 0.466 - 169.7 1 2 0 -0.0015 17 0 0 0 1.58E+07 2.15E+07 - - - 3.69 1 221125_WJC_METTL3_EV_vs_WT_F07.17953.17953.3 2.79E-06 21/64 K.HTGFLEISQHSQEFINR[166.11].L sp|Q7L0Y3|TM10C_HUMAN 1 2052.0053 0.92 104221 17953 3 2052.002017 685.009 tRNA methyltransferase 10 homolog C OS=Homo sapiens OX=9606 GN=TRMT10C PE=1 SV=2 6 2977.3 - 645773 - - - -1.5789 - 3.641 0.53 - 660.2 1 2 0 -0.0032 17 0 0 0 2.00E+07 2.18E+07 - - - 7.7127 0.9892 221125_WJC_METTL3_EV_vs_WT_F07.17954.17954.3 1.89E-05 16/40 V.GNQLGALVHQR.T sp|Q96I24|FUBP3_HUMAN 1 1191.6473 2.33 104222 17954 3 1191.646714 398.223 Far upstream element-binding protein 3 OS=Homo sapiens OX=9606 GN=FUBP3 PE=1 SV=2 9.76 2977.4 - 508796 - - - -0.4523 - 2.691 0.341 - 418.4 1 1 0 -0.0005 11 0 0 0 2.53E+07 1.08E+07 - - - 5.1538 0.8453 221125_WJC_METTL3_EV_vs_WT_F07.17958.17958.4 0.00136 16/138 E.VSNRFSGVPDRFSGSGSGTDFTLK.L "sp|A0A075B6S2|KVD29_HUMAN,sp|A0A0A0MRZ7|KVD26_HUMAN" 2 2517.2248 24.62 104224 17958 4 2517.223086 630.3135 Immunoglobulin kappa variable 2D-29 OS=Homo sapiens OX=9606 GN=IGKV2D-29 PE=3 SV=1 8.72 2977.9 - 1.56E+06 - - - -0.6869 - 2.206 0.345 - 128.6 1 1 2 -0.0017 24 0 0 0 5.60E+07 2.28E+06 - - - 2.4823 0.9999 221125_WJC_METTL3_EV_vs_WT_F07.17961.17961.4 9.57E-06 15/126 K.AHGPGLEGGLVGK[136.11]PAEFTIDTK[136.11].G "sp|O75369|FLNB_HUMAN,tr|E7EN95|E7EN95_HUMAN,tr|A0A804HK76|A0A804HK76_HUMAN,tr|A0A804HL72|A0A804HL72_HUMAN" 4 2209.1714 0.56 104227 17961 4 2209.177179 553.3001 Filamin-B OS=Homo sapiens OX=9606 GN=FLNB PE=1 SV=2 5.45 2978.2 - 467509 - - - 2.6236 - 3 0.489 - 129.2 1 2 0 0.0058 22 0 0 0 4.82E+06 8.53E+06 - - - 3.8401 1 221125_WJC_METTL3_EV_vs_WT_F07.17966.17966.4 4.68E-08 25/102 K.RPLDDGVGNQLGALVHQR.T sp|Q96I24|FUBP3_HUMAN 1 1944.029 1.88 104230 17966 4 1944.029018 487.0145 Far upstream element-binding protein 3 OS=Homo sapiens OX=9606 GN=FUBP3 PE=1 SV=2 6.75 2978.8 - 8.89E+07 - - - 0.0319 - 4.126 0.603 - 514.6 1 2 0 0.0001 18 0 0 0 2.90E+09 1.55E+09 - - - 4.96 1 221125_WJC_METTL3_EV_vs_WT_F07.17968.17968.2 1.37E-11 13/34 R.SC[160.03]GSSTPDEFPTDIPGTK[136.11].G "sp|P41091|IF2G_HUMAN,tr|H7BZU1|H7BZU1_HUMAN" 2 1902.8397 1 104232 17968 2 1902.839663 952.4271 Eukaryotic translation initiation factor 2 subunit 3 OS=Homo sapiens OX=9606 GN=EIF2S3 PE=1 SV=3 4.03 2979 - 292203 - - - -0.0053 - 2.607 0.723 - 331.2 1 2 0 0 18 0 0 0 8.94E+07 8.98E+07 - - - 6.7369 1 221125_WJC_METTL3_EV_vs_WT_F07.17969.17969.2 1.30E-10 Oct-34 R.SC[160.03]GSSTPDEFPTDIPGTK.G "sp|P41091|IF2G_HUMAN,tr|H7BZU1|H7BZU1_HUMAN" 2 1894.8255 1 104233 17969 2 1894.828417 948.42 Eukaryotic translation initiation factor 2 subunit 3 OS=Homo sapiens OX=9606 GN=EIF2S3 PE=1 SV=3 4.03 2979.1 - 285586 - - - 1.5537 - 2.409 0.736 - 221 1 2 0 0.0029 18 0 0 0 8.94E+07 8.98E+07 - - - 6.6378 0.999 221125_WJC_METTL3_EV_vs_WT_F07.17977.17977.4 0.0927 12/102 K.EMKPGFYHGHVSYLDFAK.F "sp|Q7LGA3|HS2ST_HUMAN,tr|K7EP71|K7EP71_HUMAN" 2 2125.0091 1.53 104237 17977 4 2125.005949 532.2596 Heparan sulfate 2-O-sulfotransferase 1 OS=Homo sapiens OX=9606 GN=HS2ST1 PE=1 SV=1 7.01 2980 - 805251 - - - -1.4979 - 2.23 0.294 - 88.1 1 2 0 -0.0032 18 0 0 0 3.68E+07 2.41E+07 - - - 2.0588 0.9998 221125_WJC_METTL3_EV_vs_WT_F07.17984.17984.4 6.95E-07 21/108 R.LQQHIQELEAHLEAEEGAR[166.11].Q "sp|Q7Z406|MYH14_HUMAN,tr|M0QY43|M0QY43_HUMAN" 2 2210.0955 1.38 104242 17984 4 2210.091647 553.5312 Myosin-14 OS=Homo sapiens OX=9606 GN=MYH14 PE=1 SV=2 4.62 2980.9 - 765261 - - - -1.7565 - 3.594 0.381 - 410.4 1 2 0 -0.0039 19 0 0 0 1.60E+07 1.16E+07 - - - 2.9739 0.9993 221125_WJC_METTL3_EV_vs_WT_F07.17988.17988.4 0.00647 Oct-84 K.VYNENLVHMIEHAQK.E sp|O75934|SPF27_HUMAN 1 1823.8989 1.5 104244 17988 4 1823.89519 456.982 Pre-mRNA-splicing factor SPF27 OS=Homo sapiens OX=9606 GN=BCAS2 PE=1 SV=1 6 2981.4 - 459021 - - - -2.0083 - 2 0.333 - 44.3 1 2 0 -0.0037 15 0 0 0 1.05E+07 7.00E+06 - - - 2.3714 1 221125_WJC_METTL3_EV_vs_WT_F07.17990.17990.4 1.02E-08 24/150 R.SEAALDQEQITAAYSVEHNQLEAHPK[136.11].A "sp|Q9Y520|PRC2C_HUMAN,tr|E7EPN9|E7EPN9_HUMAN" 2 2886.3875 1.78 104246 17990 4 2886.389462 722.6042 Protein PRRC2C OS=Homo sapiens OX=9606 GN=PRRC2C PE=1 SV=4 4.56 2981.6 - 516848 - - - 0.6693 - 3.582 0.589 - 139.5 1 2 0 0.0019 26 0 0 0 6.40E+07 3.60E+07 - - - 4.7546 1 221125_WJC_METTL3_EV_vs_WT_F07.17992.17992.2 6.22E-10 Oct-38 K.DHTPSQELALTQSVGGDSSA.D "sp|Q86U44|MTA70_HUMAN,tr|H0YFV6|H0YFV6_HUMAN" 2 1998.913 - 104248 17992 2 1998.906983 1000.4638 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 4.02 2981.9 - 199025 - - - -3.0316 - 2.673 0.688 - 234 1 1 0 -0.0061 20 0 0 0 - - - - - 6.5379 1 221125_WJC_METTL3_EV_vs_WT_F07.17995.17995.4 2.46E-11 31/150 R.SEAALDQEQITAAYSVEHNQLEAHPK.A "sp|Q9Y520|PRC2C_HUMAN,tr|E7EPN9|E7EPN9_HUMAN" 2 2878.3733 1.78 104249 17995 4 2878.37157 720.6006 Protein PRRC2C OS=Homo sapiens OX=9606 GN=PRRC2C PE=1 SV=4 4.56 2982.3 - 1.71E+06 - - - -0.6115 - 5.648 0.666 - 660.3 1 2 0 -0.0018 26 0 0 0 6.40E+07 3.60E+07 - - - 5.5685 1 221125_WJC_METTL3_EV_vs_WT_F07.18003.18003.3 1.52E-05 26/84 K.VTFFEPGSGDENGTSNKEDEFR.M "sp|O95793|STAU1_HUMAN,tr|Q5JW30|Q5JW30_HUMAN" 2 2461.067 2.07 104255 18003 3 2461.064582 821.3629 Double-stranded RNA-binding protein Staufen homolog 1 OS=Homo sapiens OX=9606 GN=STAU1 PE=1 SV=2 4.08 2983.3 - 1.32E+06 - - - -0.9732 - 4.285 0.654 - 608.7 1 2 1 -0.0024 22 0 0 0 2.36E+08 1.14E+08 - - - 9.2806 1 221125_WJC_METTL3_EV_vs_WT_F07.18004.18004.2 3.58E-12 18/40 K.DHTPSQELALTQSVGGDSSAD.R "sp|Q86U44|MTA70_HUMAN,tr|H0YFV6|H0YFV6_HUMAN" 2 2113.94 - 104256 18004 2 2114.93486 1057.9773 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 4.04 2983.5 - 747785 - - - 470.6255 - 3.45 0.71 - 895.2 1 1 0 0.9949 21 0 0 0 - - - - - 7.0173 1 221125_WJC_METTL3_EV_vs_WT_F07.18005.18005.3 2.03E-06 Dec-68 R.SC[160.03]GSSTPDEFPTDIPGTK.G "sp|P41091|IF2G_HUMAN,tr|H7BZU1|H7BZU1_HUMAN" 2 1894.8255 1.21 104257 18005 3 1894.82439 632.6158 Eukaryotic translation initiation factor 2 subunit 3 OS=Homo sapiens OX=9606 GN=EIF2S3 PE=1 SV=3 4.03 2983.6 - 497464 - - - -0.5716 - 2.516 0.569 - 131.5 1 2 0 -0.0011 18 0 0 0 2.94E+07 2.43E+07 - - - 7.181 1 221125_WJC_METTL3_EV_vs_WT_F07.18008.18008.4 1.20E-06 22/102 K.R[166.11]PLDDGVGNQLGALVHQR[166.11].T sp|Q96I24|FUBP3_HUMAN 1 1964.0455 1.88 104258 18008 4 1964.041676 492.0187 Far upstream element-binding protein 3 OS=Homo sapiens OX=9606 GN=FUBP3 PE=1 SV=2 6.75 2984 - 4.01E+07 - - - -1.945 - 4.056 0.538 - 410.6 1 2 0 -0.0038 18 0 0 0 2.90E+09 1.55E+09 - - - 4.3873 0.9998 221125_WJC_METTL3_EV_vs_WT_F07.18009.18009.3 0.000241 17/64 R.EKEDSLAQAGETINALK.G "sp|Q9Y6D9|MD1L1_HUMAN,tr|C9JIR0|C9JIR0_HUMAN" 2 1815.9214 2.01 104259 18009 3 1815.922075 606.3144 Mitotic spindle assembly checkpoint protein MAD1 OS=Homo sapiens OX=9606 GN=MAD1L1 PE=1 SV=2 4.41 2984.1 - 2.07E+06 - - - 0.3596 - 2.923 0.448 - 301.2 1 2 1 0.0007 17 0 0 0 4.78E+07 2.38E+07 - - - 6.2443 1 221125_WJC_METTL3_EV_vs_WT_F07.18010.18010.3 1.07E-07 23/88 A.AFASSLVSGLNSSASEPAK[136.11]EPAK[136.11].K "sp|Q86U44|MTA70_HUMAN,tr|F5H6D8|F5H6D8_HUMAN,tr|H0YFV6|H0YFV6_HUMAN,tr|B4DTN4|B4DTN4_HUMAN" 4 2263.1667 0 104260 18010 3 2263.164158 755.3962 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 6.19 2984.1 - 3.88E+06 - - - -1.1197 - 4.32 0.594 - 424.4 1 1 1 -0.0025 23 0 0 0 4.10E+05 3.57E+08 - - - 8.5945 0.9989 221125_WJC_METTL3_EV_vs_WT_F07.18011.18011.3 1.11E-07 19/84 K.VTFFEPGSGDENGTSNK[136.11]EDEFR[166.11].M "sp|O95793|STAU1_HUMAN,tr|Q5JW30|Q5JW30_HUMAN" 2 2479.0894 2.07 104261 18011 3 2479.077712 827.3704 Double-stranded RNA-binding protein Staufen homolog 1 OS=Homo sapiens OX=9606 GN=STAU1 PE=1 SV=2 4.08 2984.2 - 1.22E+06 - - - -4.7336 - 2.952 0.554 - 296.8 1 2 1 -0.0117 22 0 0 0 2.36E+08 1.14E+08 - - - 7.2797 0.9787 221125_WJC_METTL3_EV_vs_WT_F07.18012.18012.3 0.0308 Nov-56 R.ETNLDSLPLVDTHSK.R sp|P08670|VIME_HUMAN 1 1667.8366 2.2 104262 18012 3 1667.84291 556.9528 Vimentin OS=Homo sapiens OX=9606 GN=VIM PE=1 SV=4 4.54 2984.3 - 565891 - - - 3.7654 - 2.183 0.174 - 203.1 1 2 0 0.0063 15 0 0 0 9.88E+07 4.50E+07 - - - 2.5153 0.9965 221125_WJC_METTL3_EV_vs_WT_F07.18014.18014.3 0.0356 Oct-56 R.ETNLDSLPLVDTHSK[136.11].R sp|P08670|VIME_HUMAN 1 1675.8508 3.12 104264 18014 3 1675.852917 559.6242 Vimentin OS=Homo sapiens OX=9606 GN=VIM PE=1 SV=4 4.54 2984.6 - 212265 - - - 1.2453 - 1.921 0.212 - 124.8 1 2 0 0.0021 15 0 0 0 1.76E+08 5.65E+07 - - - 2.6065 1 221125_WJC_METTL3_EV_vs_WT_F07.18017.18017.3 4.29E-10 21/84 K.VPEIEVTVEGPNNNNPQTSAVR[166.11].T "sp|P78347|GTF2I_HUMAN,tr|A0A494C1K3|A0A494C1K3_HUMAN" 2 2373.18 1.63 104265 18017 3 2373.17913 792.0673 General transcription factor II-I OS=Homo sapiens OX=9606 GN=GTF2I PE=1 SV=2 4.25 2985 - 2.02E+06 - - - -0.3611 - 4.12 0.63 - 374.9 1 2 0 -0.0009 22 0 0 0 6.86E+07 4.21E+07 - - - 8.9204 1 221125_WJC_METTL3_EV_vs_WT_F07.18019.18019.3 2.65E-08 16/68 K.YVHYEIDAC[160.03]MDSEAPGSK[136.11].D "sp|Q86U44|MTA70_HUMAN,tr|H0YFV6|H0YFV6_HUMAN" 2 2078.8805 0.02 104267 18019 3 2079.874358 693.9674 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 4.31 2985.3 - 413925 - - - 478.0775 - 3.373 0.657 - 279.5 1 2 0 0.9939 18 0 0 0 3.29E+05 1.80E+07 - - - 8.6171 1 221125_WJC_METTL3_EV_vs_WT_F07.18020.18020.3 3.04E-10 17/76 K.VNNSSLIGVGYTQTLRPGVK.L "sp|P45880|VDAC2_HUMAN,tr|A0A0A0MR02|A0A0A0MR02_HUMAN" 2 2102.1484 1.8 104268 18020 3 2102.143676 701.7234 Voltage-dependent anion-selective channel protein 2 OS=Homo sapiens OX=9606 GN=VDAC2 PE=1 SV=2 9.99 2985.4 - 306075 - - - -2.2487 - 3.71 0.641 - 384.2 1 2 0 -0.0047 20 0 0 0 4.16E+06 2.31E+06 - - - 8.8658 1 221125_WJC_METTL3_EV_vs_WT_F07.18023.18023.2 1.56E-13 19/42 Y.GGGSGGGFSASSLGGGFGGGSR.G sp|P35527|K1C9_HUMAN 1 1771.7874 999 104271 18023 2 1771.785128 886.901 "Keratin, type I cytoskeletal 9 OS=Homo sapiens OX=9606 GN=KRT9 PE=1 SV=3" 9.75 2985.8 - 227412 - - - -1.2755 - 3.619 0.632 - 726.3 1 1 0 -0.0023 22 0 0 0 3.10E+07 0.00E+00 - - - 6.8704 0.9963 221125_WJC_METTL3_EV_vs_WT_F07.18028.18028.3 4.29E-06 15/68 R.HINLPLPAPHAQYAIPNR[166.11].H "sp|P42694|HELZ_HUMAN,tr|J3QS41|J3QS41_HUMAN" 2 2031.1042 2.77 104274 18028 3 2032.100603 678.042 Probable helicase with zinc finger domain OS=Homo sapiens OX=9606 GN=HELZ PE=1 SV=2 8.76 2986.4 - 268660 - - - 490.58 - 3.099 0.506 - 200.2 1 2 0 0.9964 18 0 0 0 4.12E+07 1.49E+07 - - - 6.7219 1 221125_WJC_METTL3_EV_vs_WT_F07.18031.18031.4 1.22E-07 20/102 R.HINLPLPAPHAQYAIPNR[166.11].H "sp|P42694|HELZ_HUMAN,tr|J3QS41|J3QS41_HUMAN" 2 2031.1042 2.7 104275 18031 4 2031.102776 508.7833 Probable helicase with zinc finger domain OS=Homo sapiens OX=9606 GN=HELZ PE=1 SV=2 8.76 2986.8 - 481448 - - - -0.6932 - 3.275 0.484 - 287.2 1 2 0 -0.0014 18 0 0 0 5.74E+07 2.12E+07 - - - 3.8447 0.9998 221125_WJC_METTL3_EV_vs_WT_F07.18032.18032.3 0.00166 Sep-72 R.GLLQDDAHPTLVTYADHSK[136.11].L "sp|Q86U44|MTA70_HUMAN,tr|F5H6D8|F5H6D8_HUMAN,tr|H0YFV6|H0YFV6_HUMAN,tr|B4DTN4|B4DTN4_HUMAN" 4 2088.0367 0.37 104276 18032 3 2088.033163 697.0195 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 5.13 2987 - 314878 - - - -1.7097 - 2.371 0.403 - 98.7 1 2 0 -0.0036 19 0 0 0 1.25E+06 3.36E+06 - - - 5.153 0.9999 221125_WJC_METTL3_EV_vs_WT_F07.18033.18033.3 2.75E-07 13/104 R.SVPQSGPTVR[166.11]PQEDAWASPGAYGMGGR[166.11].Y "sp|O95429|BAG4_HUMAN,tr|H0YBT1|H0YBT1_HUMAN" 2 2777.3095 0.1 104277 18033 3 2777.316558 926.7771 BAG family molecular chaperone regulator 4 OS=Homo sapiens OX=9606 GN=BAG4 PE=1 SV=1 5.79 2987.1 - 324704 - - - 2.5586 - 2.759 0.541 - 109.6 1 2 0 0.0071 27 0 0 0 6.86E+05 6.83E+06 - - - 6.9045 1 221125_WJC_METTL3_EV_vs_WT_F07.18036.18036.3 9.07E-13 21/84 K.VPEIEVTVEGPNNNNPQTSAVR.T "sp|P78347|GTF2I_HUMAN,tr|A0A494C1K3|A0A494C1K3_HUMAN" 2 2363.1717 1.63 104278 18036 3 2363.171877 788.7312 General transcription factor II-I OS=Homo sapiens OX=9606 GN=GTF2I PE=1 SV=2 4.25 2987.5 - 2.61E+06 - - - 0.0677 - 4.173 0.648 - 387.4 1 2 0 0.0002 22 0 0 0 6.86E+07 4.20E+07 - - - 9.1516 0.9996 221125_WJC_METTL3_EV_vs_WT_F07.18041.18041.3 0.00974 Nov-84 K.QLQELEDK[136.11]QNADISAMQDTINK[136.11].L sp|P07196|NFL_HUMAN 1 2547.2457 2.33 104283 18041 3 2547.246276 850.0892 Neurofilament light polypeptide OS=Homo sapiens OX=9606 GN=NEFL PE=1 SV=3 4.11 2988.1 - 381097 - - - 0.2077 - 2.272 0.424 - 110.3 1 2 1 0.0005 22 0 0 0 1.51E+07 6.48E+06 - - - 5.2127 1 221125_WJC_METTL3_EV_vs_WT_F07.18044.18044.4 2.46E-09 19/102 R.HINLPLPAPHAQYAIPNR.H "sp|P42694|HELZ_HUMAN,tr|J3QS41|J3QS41_HUMAN" 2 2021.0959 2.67 104284 18044 4 2021.096015 506.2813 Probable helicase with zinc finger domain OS=Homo sapiens OX=9606 GN=HELZ PE=1 SV=2 8.76 2988.5 - 1.32E+06 - - - 0.05 - 3.228 0.534 - 236.8 1 2 0 0.0001 18 0 0 0 5.68E+07 2.12E+07 - - - 4.2753 0.9999 221125_WJC_METTL3_EV_vs_WT_F07.18046.18046.3 2.37E-08 18/84 K.QLQELEDKQNADISAMQDTINK.L sp|P07196|NFL_HUMAN 1 2531.2173 2.33 104286 18046 3 2531.216431 844.7464 Neurofilament light polypeptide OS=Homo sapiens OX=9606 GN=NEFL PE=1 SV=3 4.11 2988.8 - 808432 - - - -0.3619 - 3.092 0.54 - 378.1 1 2 1 -0.0009 22 0 0 0 1.51E+07 6.48E+06 - - - 7.2365 0.9999 221125_WJC_METTL3_EV_vs_WT_F07.18057.18057.4 0.000829 14/108 R.GLLQDDAHPTLVTYADHSK[136.11].L "sp|Q86U44|MTA70_HUMAN,tr|F5H6D8|F5H6D8_HUMAN,tr|H0YFV6|H0YFV6_HUMAN,tr|B4DTN4|B4DTN4_HUMAN" 4 2088.0367 0.03 104295 18057 4 2088.033776 523.0165 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 5.13 2990.2 - 761294 - - - -1.4162 - 2.943 0.397 - 198.3 1 2 0 -0.003 19 0 0 0 1.16E+06 3.59E+07 - - - 3.0458 1 221125_WJC_METTL3_EV_vs_WT_F07.18058.18058.3 1.94E-16 19/88 R.SKADC[160.03]PTMEAQTTLTTNDIVISK.L sp|Q13123|RED_HUMAN 1 2523.2197 0.91 104296 18058 3 2523.220557 842.0805 Protein Red OS=Homo sapiens OX=9606 GN=IK PE=1 SV=3 4.56 2990.3 - 378183 - - - 0.3575 - 3.875 0.752 - 414.6 1 2 1 0.0009 23 0 0 0 9.42E+06 1.03E+07 - - - 10.1015 0.9996 221125_WJC_METTL3_EV_vs_WT_F07.18061.18061.4 0.000993 11/138 R.TPHFDVIVIGGGHAGTEAATAAAR[166.11].C "sp|Q9Y2Z2|MTO1_HUMAN,tr|A0A7P0T957|A0A7P0T957_HUMAN,tr|A0A7P0T9M4|A0A7P0T9M4_HUMAN,tr|A0A7P0Z471|A0A7P0Z471_HUMAN,tr|E7EWI1|E7EWI1_HUMAN,tr|H0YBI9|H0YBI9_HUMAN,tr|A0A7P0TA02|A0A7P0TA02_HUMAN,tr|A0A7P0T851|A0A7P0T851_HUMAN,tr|A0A7P0TA27|A0A7P0TA27_HUMAN,tr|A0A7P0T9S8|A0A7P0T9S8_HUMAN,tr|A0A7P0Z4D4|A0A7P0Z4D4_HUMAN,tr|A0A7P0TAK2|A0A7P0TAK2_HUMAN,tr|A0A7P0T9I0|A0A7P0T9I0_HUMAN,tr|E5RFF7|E5RFF7_HUMAN,tr|A0A7P0TBC1|A0A7P0TBC1_HUMAN,tr|A0A7P0Z482|A0A7P0Z482_HUMAN,tr|A0A7P0T8Y9|A0A7P0T8Y9_HUMAN,tr|A0A7P0TAU1|A0A7P0TAU1_HUMAN" 18 2328.185 3.8 104297 18061 4 2328.189279 583.0535 "Protein MTO1 homolog, mitochondrial OS=Homo sapiens OX=9606 GN=MTO1 PE=1 SV=2" 5.92 2990.7 - 203701 - - - 1.8323 - 2.178 0.361 - 50.6 1 2 0 0.0043 24 0 0 0 6.08E+06 1.60E+06 - - - 2.6168 0.8694 221125_WJC_METTL3_EV_vs_WT_F07.18064.18064.3 1.02E-05 13/80 K.DHTPSQELALTQSVGGDSSAD.R "sp|Q86U44|MTA70_HUMAN,tr|H0YFV6|H0YFV6_HUMAN" 2 2113.94 - 104300 18064 3 2114.940861 705.6539 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 4.04 2991.1 - 499560 - - - 473.4642 - 2.808 0.473 - 195.1 1 1 0 1.0009 21 0 0 0 - - - - - 6.0115 1 221125_WJC_METTL3_EV_vs_WT_F07.18065.18065.3 8.73E-15 15/88 R.SK[136.11]ADC[160.03]PTMEAQTTLTTNDIVISK[136.11].L sp|Q13123|RED_HUMAN 1 2539.2481 0.91 104301 18065 3 2539.250791 847.4233 Protein Red OS=Homo sapiens OX=9606 GN=IK PE=1 SV=3 4.56 2991.3 - 418278 - - - 1.0775 - 3.432 0.69 - 265.9 1 2 1 0.0027 23 0 0 0 9.42E+06 1.03E+07 - - - 9.1249 0.9762 221125_WJC_METTL3_EV_vs_WT_F07.18069.18069.3 0.0117 8/112 K.VVGDR[166.11]ENGSDNLPSSAGSGDK[136.11]PLSDPAPF.- "sp|O43399|TPD54_HUMAN,tr|A0A087WZ51|A0A087WZ51_HUMAN" 2 2902.37 2.67 104305 18069 3 2902.371634 968.4639 Tumor protein D54 OS=Homo sapiens OX=9606 GN=TPD52L2 PE=1 SV=2 4.04 2991.8 - 156047 - - - 0.5702 - 1.683 0.221 - 23.6 1 2 1 0.0017 29 0 0 0 1.96E+07 7.36E+06 - - - 2.2011 1 221125_WJC_METTL3_EV_vs_WT_F07.18072.18072.4 7.50E-10 21/108 K.K[136.11]YVATLGVEVHPLVFHTNR[166.11].G "sp|P62826|RAN_HUMAN,tr|H0YFC6|H0YFC6_HUMAN,tr|B5MDF5|B5MDF5_HUMAN,tr|J3KQE5|J3KQE5_HUMAN,tr|F5H018|F5H018_HUMAN" 5 2197.2127 0.87 104306 18072 4 2197.217974 550.3104 GTP-binding nuclear protein Ran OS=Homo sapiens OX=9606 GN=RAN PE=1 SV=3 8.6 2992.2 - 513178 - - - 2.4103 - 3.525 0.551 - 319.2 1 2 0 0.0053 19 0 0 0 1.22E+07 1.39E+07 - - - 4.4466 0.9984 221125_WJC_METTL3_EV_vs_WT_F07.18073.18073.3 2.04E-10 19/84 Y.GGGSGGGFSASSLGGGFGGGSR.G sp|P35527|K1C9_HUMAN 1 1771.7874 999 104307 18073 3 1771.789904 591.6031 "Keratin, type I cytoskeletal 9 OS=Homo sapiens OX=9606 GN=KRT9 PE=1 SV=3" 9.75 2992.3 - 763414 - - - 1.42 - 3.636 0.584 - 311.6 1 1 0 0.0025 22 0 0 0 1.07E+07 0.00E+00 - - - 8.1108 0.9998 221125_WJC_METTL3_EV_vs_WT_F07.18080.18080.3 6.85E-05 May-80 K.TQTVC[160.03]NFTDGALVQHQEWDGK.E "sp|Q01469|FABP5_HUMAN,sp|A8MUU1|FB5L3_HUMAN,tr|I6L8B7|I6L8B7_HUMAN" 3 2433.1019 6.54 104311 18080 3 2433.097439 812.0413 Fatty acid-binding protein 5 OS=Homo sapiens OX=9606 GN=FABP5 PE=1 SV=3 4.53 2993.2 - 225957 - - - -1.8429 - 2.325 0.399 - 21.4 1 2 0 -0.0045 21 0 0 0 6.87E+06 1.05E+06 - - - 5.01 0.9999 221125_WJC_METTL3_EV_vs_WT_F07.18086.18086.3 8.54E-08 18/52 K.HWPFQVINDGDK[136.11]PK[136.11].V "sp|P0DMV8|HS71A_HUMAN,sp|P0DMV9|HS71B_HUMAN,tr|A0A0G2JIW1|A0A0G2JIW1_HUMAN" 3 1695.8704 0.11 104316 18086 3 1695.874893 566.2974 Heat shock 70 kDa protein 1A OS=Homo sapiens OX=9606 GN=HSPA1A PE=1 SV=1 6.75 2993.9 - 623108 - - - 2.6553 - 2.786 0.519 - 520.6 1 2 0 0.0045 14 0 0 0 7.14E+06 6.60E+07 - - - 7.048 1 221125_WJC_METTL3_EV_vs_WT_F07.18088.18088.3 5.85E-09 19/112 K.VVGDRENGSDNLPSSAGSGDKPLSDPAPF.- "sp|O43399|TPD54_HUMAN,tr|A0A087WZ51|A0A087WZ51_HUMAN" 2 2884.3475 2.6 104317 18088 3 2884.351203 962.4564 Tumor protein D54 OS=Homo sapiens OX=9606 GN=TPD52L2 PE=1 SV=2 4.04 2994.1 - 416931 - - - 1.2807 - 3.422 0.646 - 128.2 1 2 1 0.0037 29 0 0 0 1.96E+07 7.56E+06 - - - 8.5715 1 221125_WJC_METTL3_EV_vs_WT_F07.18091.18091.3 7.87E-10 18/72 R.EGRPSGEAFVELESEDEVK.L "sp|P31943|HNRH1_HUMAN,tr|E7EQJ0|E7EQJ0_HUMAN,tr|D6RIH9|D6RIH9_HUMAN,tr|D6RJ04|D6RJ04_HUMAN,tr|D6RFM3|D6RFM3_HUMAN,tr|E9PCY7|E9PCY7_HUMAN,tr|D6RIT2|D6RIT2_HUMAN,tr|D6R9T0|D6R9T0_HUMAN,tr|D6RIU0|D6RIU0_HUMAN,tr|D6RAM1|D6RAM1_HUMAN,tr|D6RBM0|D6RBM0_HUMAN,tr|G8JLB6|G8JLB6_HUMAN,tr|D6RDL0|D6RDL0_HUMAN,tr|D6RDU3|D6RDU3_HUMAN,tr|E7EN40|E7EN40_HUMAN" 15 2105.9753 1.23 104320 18091 3 2105.984433 702.999 Heterogeneous nuclear ribonucleoprotein H OS=Homo sapiens OX=9606 GN=HNRNPH1 PE=1 SV=4 4.06 2994.5 - 265084 - - - 4.3324 - 3.857 0.599 - 495.5 1 2 0 0.0091 19 0 0 0 2.96E+07 2.41E+07 - - - 8.5321 1 221125_WJC_METTL3_EV_vs_WT_F07.18094.18094.4 1.26E-09 22/102 K.R[166.11]GAPPSSNIEDFHGLLPK[136.11].G "sp|P43243|MATR3_HUMAN,tr|A8MXP9|A8MXP9_HUMAN,tr|D6R991|D6R991_HUMAN,tr|A0A0R4J2E8|A0A0R4J2E8_HUMAN,tr|H0Y8T4|H0Y8T4_HUMAN,tr|D6REM6|D6REM6_HUMAN" 6 1952.0235 1.47 104322 18094 4 1952.026225 489.0131 Matrin-3 OS=Homo sapiens OX=9606 GN=MATR3 PE=1 SV=2 6.75 2994.9 - 6.30E+06 - - - 1.4062 - 3.586 0.574 - 278.2 1 2 0 0.0027 18 0 0 0 8.19E+08 5.58E+08 - - - 4.6588 1 221125_WJC_METTL3_EV_vs_WT_F07.18096.18096.3 4.14E-15 28/68 K.R[166.11]GAPPSSNIEDFHGLLPK[136.11].G "sp|P43243|MATR3_HUMAN,tr|A8MXP9|A8MXP9_HUMAN,tr|D6R991|D6R991_HUMAN,tr|A0A0R4J2E8|A0A0R4J2E8_HUMAN,tr|H0Y8T4|H0Y8T4_HUMAN,tr|D6REM6|D6REM6_HUMAN" 6 1952.0235 1.37 104323 18096 3 1952.02659 651.6818 Matrin-3 OS=Homo sapiens OX=9606 GN=MATR3 PE=1 SV=2 6.75 2995.1 - 3.65E+06 - - - 1.5932 - 4.618 0.691 - 1171.4 1 2 0 0.0031 18 0 0 0 5.25E+08 3.83E+08 - - - 10.0529 1 221125_WJC_METTL3_EV_vs_WT_F07.18107.18107.3 2.31E-08 21/72 R.EGR[166.11]PSGEAFVELESEDEVK[136.11].L "sp|P31943|HNRH1_HUMAN,tr|E7EQJ0|E7EQJ0_HUMAN,tr|D6RIH9|D6RIH9_HUMAN,tr|D6RJ04|D6RJ04_HUMAN,tr|D6RFM3|D6RFM3_HUMAN,tr|E9PCY7|E9PCY7_HUMAN,tr|D6RIT2|D6RIT2_HUMAN,tr|D6R9T0|D6R9T0_HUMAN,tr|D6RIU0|D6RIU0_HUMAN,tr|D6RAM1|D6RAM1_HUMAN,tr|D6RBM0|D6RBM0_HUMAN,tr|G8JLB6|G8JLB6_HUMAN,tr|D6RDL0|D6RDL0_HUMAN,tr|D6RDU3|D6RDU3_HUMAN,tr|E7EN40|E7EN40_HUMAN" 15 2123.9978 1.01 104332 18107 3 2123.999094 709.0065 Heterogeneous nuclear ribonucleoprotein H OS=Homo sapiens OX=9606 GN=HNRNPH1 PE=1 SV=4 4.06 2996.5 - 488642 - - - 0.6191 - 4.304 0.644 - 624.6 1 2 0 0.0013 19 0 0 0 9.70E+06 9.60E+06 - - - 9.3054 1 221125_WJC_METTL3_EV_vs_WT_F07.18112.18112.4 3.10E-16 25/144 K.IRYESGDHVAVYPANDSALVNQLGK.L "sp|P16435|NCPR_HUMAN,tr|H0Y4R2|H0Y4R2_HUMAN,tr|E7EMD0|E7EMD0_HUMAN" 3 2715.3616 0.81 104335 18112 4 2715.371608 679.8477 NADPH--cytochrome P450 reductase OS=Homo sapiens OX=9606 GN=POR PE=1 SV=2 5.38 2997.1 - 1.14E+06 - - - 3.6699 - 5.082 0.694 - 373.6 1 2 1 0.01 25 0 0 0 9.73E+06 1.20E+07 - - - 5.781 0.9999 221125_WJC_METTL3_EV_vs_WT_F07.18113.18113.4 6.76E-11 23/144 K.IR[166.11]YESGDHVAVYPANDSALVNQLGK[136.11].L "sp|P16435|NCPR_HUMAN,tr|H0Y4R2|H0Y4R2_HUMAN,tr|E7EMD0|E7EMD0_HUMAN" 3 2733.3841 0.81 104336 18113 4 2733.3892 684.3533 NADPH--cytochrome P450 reductase OS=Homo sapiens OX=9606 GN=POR PE=1 SV=2 5.38 2997.2 - 944741 - - - 1.8611 - 4.14 0.569 - 302.3 1 2 1 0.0051 25 0 0 0 9.73E+06 1.20E+07 - - - 4.6291 1 221125_WJC_METTL3_EV_vs_WT_F07.18114.18114.3 9.00E-08 13/84 K.FVESILSNNTTDDHC[160.03]QEFVNQK[136.11].G sp|Q7Z6Z7|HUWE1_HUMAN 1 2632.1955 0.3 104337 18114 3 2632.199575 878.4058 E3 ubiquitin-protein ligase HUWE1 OS=Homo sapiens OX=9606 GN=HUWE1 PE=1 SV=3 4.31 2997.3 - 443025 - - - 1.5497 - 2.243 0.532 - 118.2 1 2 0 0.0041 22 0 0 0 2.69E+06 8.86E+06 - - - 6.3853 0.9999 221125_WJC_METTL3_EV_vs_WT_F07.18116.18116.4 1.09E-07 20/228 R.IFPPETSASVAATPPPSTASAPAAVNSSASADKPLSNMK.L "sp|P09874|PARP1_HUMAN,tr|A0A7I2V3E1|A0A7I2V3E1_HUMAN" 2 3766.8724 1.69 104339 18116 4 3766.883122 942.7254 Poly [ADP-ribose] polymerase 1 OS=Homo sapiens OX=9606 GN=PARP1 PE=1 SV=4 6.07 2997.6 - 372493 - - - 2.8541 - 3.094 0.52 - 108.4 1 2 0 0.0108 39 0 0 0 7.39E+06 4.38E+06 - - - 4.0768 0.9998 221125_WJC_METTL3_EV_vs_WT_F07.18118.18118.3 9.12E-05 Oct-56 K.KLDESIYDVAFHSSK.A sp|Q13033|STRN3_HUMAN 1 1737.8574 21.44 104341 18118 3 1737.862219 580.2931 Striatin-3 OS=Homo sapiens OX=9606 GN=STRN3 PE=1 SV=3 5.38 2997.9 - 152533 - - - 2.7925 - 2.333 0.435 - 84.5 1 2 0 0.0049 15 0 0 0 3.78E+07 1.76E+06 - - - 5.599 1 221125_WJC_METTL3_EV_vs_WT_F07.18120.18120.3 3.41E-10 27/68 K.RPLDDGVGNQLGALVHQR.T sp|Q96I24|FUBP3_HUMAN 1 1944.029 1.87 104342 18120 3 1944.033819 649.0169 Far upstream element-binding protein 3 OS=Homo sapiens OX=9606 GN=FUBP3 PE=1 SV=2 6.75 2998.1 - 1.38E+06 - - - 2.5015 - 5.089 0.6 - 976.4 1 2 0 0.0049 18 0 0 0 2.61E+09 1.40E+09 - - - 9.2797 0.9998 221125_WJC_METTL3_EV_vs_WT_F07.18122.18122.3 5.81E-05 15/76 K.LAASGEGGLQELSGHFENQK[136.11].V "sp|Q16643|DREB_HUMAN,tr|D6RFI1|D6RFI1_HUMAN" 2 2079.0112 1.03 104343 18122 3 2079.015712 694.011 Drebrin OS=Homo sapiens OX=9606 GN=DBN1 PE=1 SV=4 4.75 2998.3 - 504296 - - - 2.1477 - 2.607 0.415 - 151.5 1 2 0 0.0045 20 0 0 0 1.04E+07 1.02E+07 - - - 5.4902 1 221125_WJC_METTL3_EV_vs_WT_F07.18124.18124.3 1.21E-10 23/68 K.DNTRPGANSPEMWSEAIK.L "sp|Q92499|DDX1_HUMAN,tr|A0A087X2G1|A0A087X2G1_HUMAN,tr|A0A7I2V430|A0A7I2V430_HUMAN,tr|A0A7I2V4F0|A0A7I2V4F0_HUMAN,tr|A0A087WZ71|A0A087WZ71_HUMAN,tr|A0A7I2YQ77|A0A7I2YQ77_HUMAN" 6 2001.9214 1.73 104345 18124 3 2001.926531 668.3144 ATP-dependent RNA helicase DDX1 OS=Homo sapiens OX=9606 GN=DDX1 PE=1 SV=2 4.68 2998.5 - 1.92E+06 - - - 2.5436 - 4.183 0.623 - 800 1 2 0 0.0051 18 0 0 0 1.05E+08 6.08E+07 - - - 9.0478 1 221125_WJC_METTL3_EV_vs_WT_F07.18126.18126.3 1.05E-08 16/72 R.GNHETDNMNQIYGFEGEVK.A "sp|P53041|PPP5_HUMAN,tr|H0YDU8|H0YDU8_HUMAN,tr|A8MU39|A8MU39_HUMAN" 3 2180.9433 0.6 104347 18126 3 2180.944435 727.9884 Serine\threonine-protein phosphatase 5 OS=Homo sapiens OX=9606 GN=PPP5C PE=1 SV=1 4.4 2998.8 - 363422 - - - 0.5218 - 3.162 0.633 - 287.9 1 2 0 0.0011 19 0 0 0 5.63E+06 9.32E+06 - - - 8.4253 0.9999 221125_WJC_METTL3_EV_vs_WT_F07.18128.18128.3 0.36 15/100 R.VVEC[160.03]KPQPC[160.03]VVSVEGLSSSTTDAQLK.S "sp|Q96EV2|RBM33_HUMAN,tr|H0Y3K4|H0Y3K4_HUMAN,tr|A0A0C4DFS3|A0A0C4DFS3_HUMAN" 3 2817.3888 0.3 104349 18128 3 2817.396358 940.1369 RNA-binding protein 33 OS=Homo sapiens OX=9606 GN=RBM33 PE=1 SV=3 4.68 2999 - 163036 - - - 2.6663 - 2.886 0.456 - 155.9 1 2 0 0.0075 26 0 0 0 1.01E+06 3.41E+06 - - - 6.0602 0.9984 221125_WJC_METTL3_EV_vs_WT_F07.18132.18132.3 1.20E-06 17/72 K.EFQQPSQITESTIHEIPTK[136.11].D "sp|Q5SW79|CE170_HUMAN,tr|H0Y2V6|H0Y2V6_HUMAN" 2 2220.1154 2.13 104351 18132 3 2220.133388 741.0457 Centrosomal protein of 170 kDa OS=Homo sapiens OX=9606 GN=CEP170 PE=1 SV=1 4.75 2999.5 - 825054 - - - 8.1122 - 2.906 0.546 - 287.4 1 2 0 0.018 19 0 0 0 1.21E+07 5.67E+06 - - - 7.2432 0.9999 221125_WJC_METTL3_EV_vs_WT_F07.18135.18135.3 4.37E-06 18/76 K.LAASGEGGLQELSGHFENQK.V "sp|Q16643|DREB_HUMAN,tr|D6RFI1|D6RFI1_HUMAN" 2 2070.997 0.64 104354 18135 3 2071.004494 691.3396 Drebrin OS=Homo sapiens OX=9606 GN=DBN1 PE=1 SV=4 4.75 2999.9 - 577761 - - - 3.5959 - 3.272 0.509 - 299.1 1 2 0 0.0074 20 0 0 0 7.74E+06 1.20E+07 - - - 7.0886 0.922 221125_WJC_METTL3_EV_vs_WT_F07.18139.18139.4 0.0178 Nov-90 P.DSHQLFIGNLPHEVDK.S "sp|Q13283|G3BP1_HUMAN,tr|A0A7I2V5M7|A0A7I2V5M7_HUMAN,tr|A0A7I2V2X7|A0A7I2V2X7_HUMAN,tr|A0A7P0P2U7|A0A7P0P2U7_HUMAN,tr|A0A7I2YQN9|A0A7I2YQN9_HUMAN,tr|A0A7I2YQH0|A0A7I2YQH0_HUMAN" 6 1847.9166 1.54 104358 18139 4 1847.918311 462.9864 Ras GTPase-activating protein-binding protein 1 OS=Homo sapiens OX=9606 GN=G3BP1 PE=1 SV=1 5.21 3000.4 - 190408 - - - 0.9194 - 1.862 0.317 - 74.8 1 1 0 0.0017 16 0 0 0 2.59E+06 1.68E+06 - - - 2.2037 0.9999 221125_WJC_METTL3_EV_vs_WT_F07.18141.18141.4 1.17E-07 16/102 K.RGAPPSSNIEDFHGLLPK.G "sp|P43243|MATR3_HUMAN,tr|A8MXP9|A8MXP9_HUMAN,tr|D6R991|D6R991_HUMAN,tr|A0A0R4J2E8|A0A0R4J2E8_HUMAN,tr|H0Y8T4|H0Y8T4_HUMAN,tr|D6REM6|D6REM6_HUMAN" 6 1934.001 1.45 104359 18141 4 1934.00693 484.5075 Matrin-3 OS=Homo sapiens OX=9606 GN=MATR3 PE=1 SV=2 6.75 3000.7 - 6.27E+06 - - - 3.061 - 3.115 0.579 - 106.8 1 2 0 0.0059 18 0 0 0 7.44E+08 5.14E+08 - - - 4.6532 1 221125_WJC_METTL3_EV_vs_WT_F07.18146.18146.3 2.70E-06 21/68 K.R[166.11]PLDDGVGNQLGALVHQR[166.11].T sp|Q96I24|FUBP3_HUMAN 1 1964.0455 1.87 104364 18146 3 1964.047288 655.6891 Far upstream element-binding protein 3 OS=Homo sapiens OX=9606 GN=FUBP3 PE=1 SV=2 6.75 3001.2 - 452133 - - - 0.9124 - 4.152 0.59 - 447 1 2 0 0.0018 18 0 0 0 2.61E+09 1.40E+09 - - - 8.6623 0.9999 221125_WJC_METTL3_EV_vs_WT_F07.18148.18148.3 4.50E-07 Nov-84 K.FVESILSNNTTDDHC[160.03]QEFVNQK.G sp|Q7Z6Z7|HUWE1_HUMAN 1 2624.1813 0.3 104366 18148 3 2624.172279 875.7344 E3 ubiquitin-protein ligase HUWE1 OS=Homo sapiens OX=9606 GN=HUWE1 PE=1 SV=3 4.31 3001.5 - 305866 - - - -3.4361 - 2.493 0.622 - 82.3 1 2 0 -0.009 22 0 0 0 2.69E+06 8.86E+06 - - - 7.6379 0.9999 221125_WJC_METTL3_EV_vs_WT_F07.18151.18151.3 7.54E-06 Aug-92 K.ALNVTVDVQSPAC[160.03]TSYQMTPQGHR.A sp|Q9NQS7|INCE_HUMAN 1 2659.2483 1.52 104369 18151 3 2659.253469 887.4234 Inner centromere protein OS=Homo sapiens OX=9606 GN=INCENP PE=1 SV=3 6.78 3001.9 - 230835 - - - 1.9551 - 2.083 0.533 - 55.2 1 2 0 0.0052 24 0 0 0 2.40E+06 1.58E+06 - - - 6.1853 0.9918 221125_WJC_METTL3_EV_vs_WT_F07.18152.18152.3 0.0605 Nov-56 K.HFC[160.03]PNVPIILVGNK[136.11]K[136.11].D "sp|P61586|RHOA_HUMAN,sp|P08134|RHOC_HUMAN,tr|E9PQH6|E9PQH6_HUMAN,tr|C9JNR4|C9JNR4_HUMAN,tr|A0A7I2V3G1|A0A7I2V3G1_HUMAN,tr|Q5JR08|Q5JR08_HUMAN,tr|C9JX21|C9JX21_HUMAN,tr|Q5JR05|Q5JR05_HUMAN,tr|Q5JR07|Q5JR07_HUMAN" 9 1750.9887 1.49 104370 18152 3 1750.994056 584.6702 Transforming protein RhoA OS=Homo sapiens OX=9606 GN=RHOA PE=1 SV=1 9.31 3002 - 271777 - - - 3.0411 - 1.538 0.282 - 127 1 2 0 0.0053 15 0 0 0 3.71E+06 2.49E+06 - - - 2.8058 0.9999 221125_WJC_METTL3_EV_vs_WT_F07.18155.18155.3 6.21E-07 13/60 K.SRQEINFWVEC[160.03]QSQGK.L sp|Q96P63|SPB12_HUMAN 1 1994.9269 3.83 104371 18155 3 1994.92694 665.9829 Serpin B12 OS=Homo sapiens OX=9606 GN=SERPINB12 PE=1 SV=1 5.86 3002.4 - 652730 - - - 0.0406 - 3.027 0.553 - 224.8 1 2 1 0.0001 16 0 0 0 3.75E+07 9.78E+06 - - - 7.5473 1 221125_WJC_METTL3_EV_vs_WT_F07.18156.18156.4 1.79E-08 14/78 K.HWPFMVVNDAGR[166.11]PK[136.11].V "sp|P11142|HSP7C_HUMAN,tr|E9PQQ4|E9PQQ4_HUMAN,tr|E9PNE6|E9PNE6_HUMAN,tr|E9PKE3|E9PKE3_HUMAN,tr|E9PN89|E9PN89_HUMAN,tr|E9PLF4|E9PLF4_HUMAN,tr|E9PK54|E9PK54_HUMAN,tr|E9PN25|E9PN25_HUMAN,tr|E9PPY6|E9PPY6_HUMAN,tr|E9PQK7|E9PQK7_HUMAN" 10 1670.847 0.18 104372 18156 4 1670.845677 418.719 Heat shock cognate 71 kDa protein OS=Homo sapiens OX=9606 GN=HSPA8 PE=1 SV=1 8.75 3002.5 - 454813 - - - -0.8134 - 2.466 0.601 - 202.9 1 2 0 -0.0014 14 0 0 0 3.85E+06 2.09E+07 - - - 4.7852 1 221125_WJC_METTL3_EV_vs_WT_F07.18160.18160.4 1.09E-05 Oct-84 K.HFC[160.03]PNVPIILVGNKK.D "sp|P61586|RHOA_HUMAN,sp|P08134|RHOC_HUMAN,tr|E9PQH6|E9PQH6_HUMAN,tr|C9JNR4|C9JNR4_HUMAN,tr|A0A7I2V3G1|A0A7I2V3G1_HUMAN,tr|Q5JR08|Q5JR08_HUMAN,tr|C9JX21|C9JX21_HUMAN,tr|Q5JR05|Q5JR05_HUMAN,tr|Q5JR07|Q5JR07_HUMAN" 9 1734.9603 1.2 104376 18160 4 1734.959348 434.7474 Transforming protein RhoA OS=Homo sapiens OX=9606 GN=RHOA PE=1 SV=1 9.31 3003.1 - 311888 - - - -0.5666 - 1.839 0.483 - 71.7 1 2 0 -0.001 15 0 0 0 4.04E+06 3.37E+06 - - - 3.6477 0.9999 221125_WJC_METTL3_EV_vs_WT_F07.18163.18163.4 0.00173 14/78 K.DSQQFHLVPVHLDR.V sp|Q9H1E1|RNAS7_HUMAN 1 1689.8587 43.28 104377 18163 4 1689.857019 423.472 Ribonuclease 7 OS=Homo sapiens OX=9606 GN=RNASE7 PE=1 SV=2 5.98 3003.5 - 1.37E+06 - - - -0.9965 - 2.568 0.412 - 206.1 1 2 0 -0.0017 14 0 0 0 6.24E+07 1.44E+06 - - - 3.1548 0.9984 221125_WJC_METTL3_EV_vs_WT_F07.18164.18164.3 0.000263 13/108 R.ITTLSPMGSGAAPSEESSSQVLPSSSQR.L sp|Q9P2N6|KANL3_HUMAN 1 2790.3342 4.62 104378 18164 3 2790.34807 931.1187 KAT8 regulatory NSL complex subunit 3 OS=Homo sapiens OX=9606 GN=KANSL3 PE=1 SV=2 4.53 3003.6 - 253984 - - - 4.9826 - 2.176 0.441 - 68.1 1 2 0 0.0139 28 0 0 0 1.07E+07 2.31E+06 - - - 5.2416 0.9999 221125_WJC_METTL3_EV_vs_WT_F07.18166.18166.3 3.35E-06 Dec-84 K.ELENEENQEEQGLEEK[136.11]GEEFAR[166.11].M sp|Q8IWE2|NXP20_HUMAN 1 2653.1746 3.66 104380 18166 3 2653.169546 885.3988 Protein NOXP20 OS=Homo sapiens OX=9606 GN=FAM114A1 PE=1 SV=2 3.92 3003.8 - 177218 - - - -1.9173 - 2.826 0.595 - 105.1 1 2 1 -0.0051 22 0 0 0 1.55E+07 4.23E+06 - - - 7.6352 1 221125_WJC_METTL3_EV_vs_WT_F07.18175.18175.3 7.94E-09 16/52 K.HWPFMVVNDAGR[166.11]PK[136.11].V "sp|P11142|HSP7C_HUMAN,tr|E9PQQ4|E9PQQ4_HUMAN,tr|E9PNE6|E9PNE6_HUMAN,tr|E9PKE3|E9PKE3_HUMAN,tr|E9PN89|E9PN89_HUMAN,tr|E9PLF4|E9PLF4_HUMAN,tr|E9PK54|E9PK54_HUMAN,tr|E9PN25|E9PN25_HUMAN,tr|E9PPY6|E9PPY6_HUMAN,tr|E9PQK7|E9PQK7_HUMAN" 10 1670.847 0.1 104385 18175 3 1670.845209 557.9563 Heat shock cognate 71 kDa protein OS=Homo sapiens OX=9606 GN=HSPA8 PE=1 SV=1 8.75 3004.9 - 1.18E+06 - - - -1.0935 - 3.177 0.522 - 391.6 1 2 0 -0.0018 14 0 0 0 6.79E+06 7.07E+07 - - - 7.4312 1 221125_WJC_METTL3_EV_vs_WT_F07.18177.18177.3 6.90E-11 19/72 R.YHTSQSGDEMTSLSEYVSR[166.11].M sp|P08238|HS90B_HUMAN 1 2185.9461 0.74 104387 18177 3 2185.94595 729.656 Heat shock protein HSP 90-beta OS=Homo sapiens OX=9606 GN=HSP90AB1 PE=1 SV=4 4.65 3005.2 - 561349 - - - -0.0901 - 3.64 0.714 - 488.2 1 2 0 -0.0002 19 0 0 0 4.53E+08 6.15E+08 - - - 9.6745 1 221125_WJC_METTL3_EV_vs_WT_F07.18178.18178.4 8.60E-06 20/192 R.ESAAPAAAPTAEAPPPSVVTRPEPQALPSPAIR.A "sp|Q92841|DDX17_HUMAN,tr|A0A5H1ZRQ2|A0A5H1ZRQ2_HUMAN,tr|A0A1X7SBZ2|A0A1X7SBZ2_HUMAN" 3 3245.7044 1.16 104388 18178 4 3245.700913 812.4334 Probable ATP-dependent RNA helicase DDX17 OS=Homo sapiens OX=9606 GN=DDX17 PE=1 SV=2 4.79 3005.3 - 543038 - - - -1.087 - 3.537 0.555 - 148.1 1 2 0 -0.0035 33 0 0 0 8.02E+07 6.91E+07 - - - 4.4348 1 221125_WJC_METTL3_EV_vs_WT_F07.18180.18180.3 4.11E-13 27/68 K.RGAPPSSNIEDFHGLLPK.G "sp|P43243|MATR3_HUMAN,tr|A8MXP9|A8MXP9_HUMAN,tr|D6R991|D6R991_HUMAN,tr|A0A0R4J2E8|A0A0R4J2E8_HUMAN,tr|H0Y8T4|H0Y8T4_HUMAN,tr|D6REM6|D6REM6_HUMAN" 6 1934.001 1.56 104389 18180 3 1933.999697 645.6743 Matrin-3 OS=Homo sapiens OX=9606 GN=MATR3 PE=1 SV=2 6.75 3005.5 - 1.79E+06 - - - -0.6789 - 4.622 0.697 - 1089.5 1 2 0 -0.0013 18 0 0 0 5.01E+07 3.21E+07 - - - 10.1224 1 221125_WJC_METTL3_EV_vs_WT_F07.18184.18184.3 5.42E-06 14/128 R.ESAAPAAAPTAEAPPPSVVTR[166.11]PEPQALPSPAIR[166.11].A "sp|Q92841|DDX17_HUMAN,tr|A0A5H1ZRQ2|A0A5H1ZRQ2_HUMAN,tr|A0A1X7SBZ2|A0A1X7SBZ2_HUMAN" 3 3265.721 1.52 104392 18184 3 3265.715575 1089.5809 Probable ATP-dependent RNA helicase DDX17 OS=Homo sapiens OX=9606 GN=DDX17 PE=1 SV=2 4.79 3006 - 872385 - - - -1.6554 - 2.398 0.525 - 71.4 1 2 0 -0.0054 33 0 0 0 1.24E+08 8.16E+07 - - - 6.404 0.9995 221125_WJC_METTL3_EV_vs_WT_F07.18191.18191.4 4.85E-08 15/120 K.EAMEDGEIDGNK[136.11]VTLDWAK[136.11]PK[136.11].G "sp|P19338|NUCL_HUMAN,tr|A0A7I2V699|A0A7I2V699_HUMAN,tr|A0A7I2V3F3|A0A7I2V3F3_HUMAN,tr|A0A7I2V428|A0A7I2V428_HUMAN,tr|H7BY16|H7BY16_HUMAN,tr|C9JLB1|C9JLB1_HUMAN" 6 2369.1635 1.06 104397 18191 4 2369.155576 593.2982 Nucleolin OS=Homo sapiens OX=9606 GN=NCL PE=1 SV=3 4.3 3006.7 - 1.76E+06 - - - -3.356 - 2.834 0.515 - 145 1 2 1 -0.008 21 0 0 0 2.36E+08 2.22E+08 - - - 4.0508 1 221125_WJC_METTL3_EV_vs_WT_F07.18192.18192.3 1.78E-12 20/72 R.YHTSQSGDEMTSLSEYVSR.M sp|P08238|HS90B_HUMAN 1 2175.9379 0.74 104398 18192 3 2175.93418 726.3199 Heat shock protein HSP 90-beta OS=Homo sapiens OX=9606 GN=HSP90AB1 PE=1 SV=4 4.65 3006.8 - 1.33E+06 - - - -1.699 - 3.915 0.723 - 449.3 1 2 0 -0.0037 19 0 0 0 4.52E+08 6.14E+08 - - - 9.9528 0.9999 221125_WJC_METTL3_EV_vs_WT_F07.18196.18196.3 2.76E-05 14/128 R.ESAAPAAAPTAEAPPPSVVTRPEPQALPSPAIR.A "sp|Q92841|DDX17_HUMAN,tr|A0A5H1ZRQ2|A0A5H1ZRQ2_HUMAN,tr|A0A1X7SBZ2|A0A1X7SBZ2_HUMAN" 3 3245.7044 1.52 104400 18196 3 3245.705827 1082.9088 Probable ATP-dependent RNA helicase DDX17 OS=Homo sapiens OX=9606 GN=DDX17 PE=1 SV=2 4.79 3007.2 - 1.35E+06 - - - 0.427 - 1.959 0.496 - 42.5 1 2 0 0.0014 33 0 0 0 1.24E+08 8.16E+07 - - - 5.6166 1 221125_WJC_METTL3_EV_vs_WT_F07.18197.18197.4 3.82E-07 25/192 R.ESAAPAAAPTAEAPPPSVVTR[166.11]PEPQALPSPAIR[166.11].A "sp|Q92841|DDX17_HUMAN,tr|A0A5H1ZRQ2|A0A5H1ZRQ2_HUMAN,tr|A0A1X7SBZ2|A0A1X7SBZ2_HUMAN" 3 3265.721 1.16 104401 18197 4 3265.712758 817.4375 Probable ATP-dependent RNA helicase DDX17 OS=Homo sapiens OX=9606 GN=DDX17 PE=1 SV=2 4.79 3007.4 - 1.11E+06 - - - -2.518 - 3.372 0.578 - 208.9 1 2 0 -0.0082 33 0 0 0 8.02E+07 6.91E+07 - - - 4.6193 0.9996 221125_WJC_METTL3_EV_vs_WT_F07.18203.18203.3 1.04E-09 17/84 K.ELENEENQEEQGLEEKGEEFAR.M sp|Q8IWE2|NXP20_HUMAN 1 2635.1522 3.57 104404 18203 3 2635.140953 879.3913 Protein NOXP20 OS=Homo sapiens OX=9606 GN=FAM114A1 PE=1 SV=2 3.92 3008.1 - 1.02E+06 - - - -4.254 - 3.239 0.635 - 186.6 1 2 1 -0.0112 22 0 0 0 1.56E+07 4.36E+06 - - - 8.4029 1 221125_WJC_METTL3_EV_vs_WT_F07.18204.18204.3 4.67E-11 20/72 R.AK[136.11]DVDK[136.11]EEALQMEAEALAK[136.11].L "sp|O00443|P3C2A_HUMAN,tr|A0A0C4DGF9|A0A0C4DGF9_HUMAN,tr|E9PPP3|E9PPP3_HUMAN" 3 2112.0835 2.87 104405 18204 3 2112.076241 705.0351 Phosphatidylinositol 4-phosphate 3-kinase C2 domain-containing subunit alpha OS=Homo sapiens OX=9606 GN=PIK3C2A PE=1 SV=2 4.36 3008.2 - 651122 - - - -3.4303 - 4.21 0.599 - 710 1 2 2 -0.0072 19 0 0 0 6.12E+07 2.13E+07 - - - 8.7478 0.9999 221125_WJC_METTL3_EV_vs_WT_F07.18205.18205.3 4.64E-06 14/92 R.QEQATEENAGVPVGPHLSLAYEDK[136.11].Q sp|Q96ST3|SIN3A_HUMAN 1 2589.2438 0.69 104406 18205 3 2589.236185 864.0886 Paired amphipathic helix protein Sin3a OS=Homo sapiens OX=9606 GN=SIN3A PE=1 SV=2 4.25 3008.4 - 797666 - - - -2.9511 - 2.339 0.524 - 152.7 1 2 0 -0.0076 24 0 0 0 9.89E+06 1.44E+07 - - - 6.3535 1 221125_WJC_METTL3_EV_vs_WT_F07.18210.18210.4 4.12E-10 26/102 K.RPLDDGVGNQLGALVHQR.T sp|Q96I24|FUBP3_HUMAN 1 1944.029 2.07 104408 18210 4 1944.025658 487.0145 Far upstream element-binding protein 3 OS=Homo sapiens OX=9606 GN=FUBP3 PE=1 SV=2 6.75 3009 - 2.00E+06 - - - -1.6965 - 4.506 0.581 - 582.5 1 2 0 -0.0033 18 0 0 0 7.50E+07 3.63E+07 - - - 4.7978 0.9998 221125_WJC_METTL3_EV_vs_WT_F07.18216.18216.4 1.23E-08 17/108 R.AK[136.11]DVDK[136.11]EEALQMEAEALAK[136.11].L "sp|O00443|P3C2A_HUMAN,tr|A0A0C4DGF9|A0A0C4DGF9_HUMAN,tr|E9PPP3|E9PPP3_HUMAN" 3 2112.0835 3.92 104412 18216 4 2112.081617 529.0281 Phosphatidylinositol 4-phosphate 3-kinase C2 domain-containing subunit alpha OS=Homo sapiens OX=9606 GN=PIK3C2A PE=1 SV=2 4.36 3009.6 - 1.19E+06 - - - -0.8849 - 3.542 0.463 - 268.7 1 2 2 -0.0019 19 0 0 0 9.16E+07 2.33E+07 - - - 3.6833 0.9958 221125_WJC_METTL3_EV_vs_WT_F07.18222.18222.3 2.90E-06 22/120 D.SPVPTAPTSGGPK[136.11]PSTASAVPELATDPELEK[136.11].K "sp|Q86U44|MTA70_HUMAN,tr|B4E349|B4E349_HUMAN,tr|F5H6D8|F5H6D8_HUMAN,tr|B4DTN4|B4DTN4_HUMAN" 4 3046.5681 0 104416 18222 3 3046.562346 1016.53 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 4.41 3010.4 - 1.04E+07 - - - -1.8975 - 3.091 0.51 - 207.7 1 1 0 -0.0058 31 0 0 0 8.00E+05 6.89E+08 - - - 6.8207 1 221125_WJC_METTL3_EV_vs_WT_F07.18234.18234.3 3.83E-11 17/80 K.NSC[160.03]IVC[160.03]NMGHSNTEIDVTSLR[166.11].T sp|O43865|SAHH2_HUMAN 1 2416.0809 0.73 104423 18234 3 2416.0822 806.3676 S-adenosylhomocysteine hydrolase-like protein 1 OS=Homo sapiens OX=9606 GN=AHCYL1 PE=1 SV=2 5.32 3011.9 - 614397 - - - 0.5447 - 3.617 0.685 - 422.2 1 2 0 0.0013 21 0 0 0 4.55E+06 6.25E+06 - - - 9.259 0.8259 221125_WJC_METTL3_EV_vs_WT_F07.18239.18239.4 2.73 6/120 K.SQGR[166.11]GSSC[160.03]SSSETSDDDSESR[166.11].R "sp|Q9NRH2|SNRK_HUMAN,tr|E7EUC4|E7EUC4_HUMAN" 2 2239.8634 0 104425 18239 4 2239.859703 560.9731 SNF-related serine\threonine-protein kinase OS=Homo sapiens OX=9606 GN=SNRK PE=1 SV=2 4.1 3012.6 - 2.29E+06 - - - -1.6639 - 0.916 0.169 - 13.2 1 2 1 -0.0037 21 0 0 0 1.23E+05 5.22E+07 - - - 0.6669 1 221125_WJC_METTL3_EV_vs_WT_F07.18240.18240.4 6.10E-07 21/132 K.SVEMHHEALSEALPGDNVGFNVK[136.11].N "sp|Q05639|EF1A2_HUMAN,sp|P68104|EF1A1_HUMAN,tr|A0A7I2V659|A0A7I2V659_HUMAN,tr|A0A7I2V3H3|A0A7I2V3H3_HUMAN,tr|A0A2U3TZH3|A0A2U3TZH3_HUMAN,tr|A0A7I2V5N4|A0A7I2V5N4_HUMAN,tr|A0A087WVQ9|A0A087WVQ9_HUMAN,tr|A0A087WV01|A0A087WV01_HUMAN" 8 2487.1944 0.43 104426 18240 4 2487.189952 622.8059 Elongation factor 1-alpha 2 OS=Homo sapiens OX=9606 GN=EEF1A2 PE=1 SV=1 4.8 3012.7 - 1.60E+06 - - - -1.7775 - 4.008 0.598 - 310.6 1 2 0 -0.0044 23 0 0 0 1.34E+08 3.13E+08 - - - 4.8796 1 221125_WJC_METTL3_EV_vs_WT_F07.18243.18243.3 5.31E-13 23/84 K.FMC[160.03]EVQVEGYNYTGMGNSTNK[136.11]K[136.11].D sp|Q08211|DHX9_HUMAN 1 2572.1367 0.67 104427 18243 3 2572.130734 858.3862 ATP-dependent RNA helicase A OS=Homo sapiens OX=9606 GN=DHX9 PE=1 SV=4 6.13 3013.1 - 1.61E+06 - - - -2.3311 - 4.382 0.765 - 466.9 1 2 0 -0.006 22 0 0 0 2.21E+07 3.31E+07 - - - 10.5703 1 221125_WJC_METTL3_EV_vs_WT_F07.18246.18246.3 1.13E-14 29/104 R.R[166.11]GAYGGGYGGYDDYNGYNDGYGFGSDR[166.11].F "sp|P31943|HNRH1_HUMAN,tr|H0YBD7|H0YBD7_HUMAN,tr|H0YB39|H0YB39_HUMAN,tr|E9PCY7|E9PCY7_HUMAN,tr|G8JLB6|G8JLB6_HUMAN" 5 2892.1551 1.11 104429 18246 3 2892.141476 965.059 Heterogeneous nuclear ribonucleoprotein H OS=Homo sapiens OX=9606 GN=HNRNPH1 PE=1 SV=4 4.14 3013.5 - 1.00E+06 - - - -4.7172 - 5.011 0.8 - 1069.3 1 2 0 -0.0136 27 0 0 0 5.52E+07 4.97E+07 - - - 11.1632 1 221125_WJC_METTL3_EV_vs_WT_F07.18247.18247.3 1.01E-10 29/104 R.RGAYGGGYGGYDDYNGYNDGYGFGSDR.F "sp|P31943|HNRH1_HUMAN,tr|H0YBD7|H0YBD7_HUMAN,tr|H0YB39|H0YB39_HUMAN,tr|E9PCY7|E9PCY7_HUMAN,tr|G8JLB6|G8JLB6_HUMAN" 5 2872.1386 1.11 104430 18247 3 2872.139225 958.3868 Heterogeneous nuclear ribonucleoprotein H OS=Homo sapiens OX=9606 GN=HNRNPH1 PE=1 SV=4 4.14 3013.6 - 1.06E+06 - - - 0.2249 - 4.909 0.717 - 1092.8 1 2 0 0.0006 27 0 0 0 5.52E+07 4.97E+07 - - - 10.1941 0.9738 221125_WJC_METTL3_EV_vs_WT_F07.18252.18252.3 0.00112 Sep-72 K.K[136.11]QSK[136.11]PVTTPEEIAQVATIS.A "sp|P10809|CH60_HUMAN,tr|A0A7I2V599|A0A7I2V599_HUMAN,tr|E7EXB4|E7EXB4_HUMAN,tr|A0A7I2YQ71|A0A7I2YQ71_HUMAN,tr|E7ESH4|E7ESH4_HUMAN,tr|A0A7I2V5M1|A0A7I2V5M1_HUMAN,tr|A0A7I2V5K3|A0A7I2V5K3_HUMAN,tr|A0A7I2V369|A0A7I2V369_HUMAN" 8 2042.123 1.54 104433 18252 3 2042.121019 681.715 "60 kDa heat shock protein, mitochondrial OS=Homo sapiens OX=9606 GN=HSPD1 PE=1 SV=2" 6.14 3014.1 - 484237 - - - -0.9877 - 2.029 0.366 - 72.7 1 1 0 -0.002 19 0 0 0 3.07E+07 1.99E+07 - - - 4.3583 1 221125_WJC_METTL3_EV_vs_WT_F07.18257.18257.3 8.56E-15 24/84 K.FMC[160.03]EVQVEGYNYTGMGNSTNKK.D sp|Q08211|DHX9_HUMAN 1 2556.1083 0.67 104436 18257 3 2556.104317 853.0434 ATP-dependent RNA helicase A OS=Homo sapiens OX=9606 GN=DHX9 PE=1 SV=4 6.13 3014.8 - 995984 - - - -1.57 - 3.777 0.755 - 453.4 1 2 0 -0.004 22 0 0 0 2.21E+07 3.31E+07 - - - 10.1071 1 221125_WJC_METTL3_EV_vs_WT_F07.18263.18263.3 1.08E-10 18/80 K.EAMEDGEIDGNK[136.11]VTLDWAK[136.11]PK[136.11].G "sp|P19338|NUCL_HUMAN,tr|A0A7I2V699|A0A7I2V699_HUMAN,tr|A0A7I2V3F3|A0A7I2V3F3_HUMAN,tr|A0A7I2V428|A0A7I2V428_HUMAN,tr|H7BY16|H7BY16_HUMAN,tr|C9JLB1|C9JLB1_HUMAN" 6 2369.1635 0.99 104440 18263 3 2369.158502 790.7285 Nucleolin OS=Homo sapiens OX=9606 GN=NCL PE=1 SV=3 4.3 3015.6 - 1.27E+06 - - - -2.121 - 3.66 0.715 - 343.4 1 2 1 -0.005 21 0 0 0 6.24E+07 6.33E+07 - - - 9.6208 0.9999 221125_WJC_METTL3_EV_vs_WT_F07.18266.18266.4 2.77E-09 26/114 K.AR[166.11]PFPDGLAEDIDK[136.11]GEVSAR[166.11].Q sp|P13639|EF2_HUMAN 1 2170.1013 0.53 104443 18266 4 2170.100472 543.5326 Elongation factor 2 OS=Homo sapiens OX=9606 GN=EEF2 PE=1 SV=4 4.44 3016 - 559944 - - - -0.3751 - 4.043 0.601 - 651.5 1 2 1 -0.0008 20 0 0 0 1.24E+08 2.33E+08 - - - 4.9239 1 221125_WJC_METTL3_EV_vs_WT_F07.18272.18272.3 2.55E-16 30/88 K.SVEMHHEALSEALPGDNVGFNVK.N "sp|Q05639|EF1A2_HUMAN,sp|P68104|EF1A1_HUMAN,tr|A0A7I2V659|A0A7I2V659_HUMAN,tr|A0A7I2V3H3|A0A7I2V3H3_HUMAN,tr|A0A2U3TZH3|A0A2U3TZH3_HUMAN,tr|A0A7I2V5N4|A0A7I2V5N4_HUMAN,tr|A0A087WVQ9|A0A087WVQ9_HUMAN,tr|A0A087WV01|A0A087WV01_HUMAN" 8 2479.1802 0.31 104447 18272 3 2479.179203 827.4007 Elongation factor 1-alpha 2 OS=Homo sapiens OX=9606 GN=EEF1A2 PE=1 SV=1 4.8 3016.8 - 1.28E+06 - - - -0.3913 - 5.066 0.618 - 1057.1 1 2 0 -0.001 23 0 0 0 3.42E+07 1.12E+08 - - - 9.2362 0.9985 221125_WJC_METTL3_EV_vs_WT_F07.18277.18277.4 0.000602 14/102 R.QEFAQHANAFHQWIQETR[166.11].T "sp|Q13813|SPTN1_HUMAN,tr|A0A0D9SF54|A0A0D9SF54_HUMAN,tr|A0A0D9SGF6|A0A0D9SGF6_HUMAN" 3 2250.0594 1.58 104450 18277 4 2250.066579 563.5221 "Spectrin alpha chain, non-erythrocytic 1 OS=Homo sapiens OX=9606 GN=SPTAN1 PE=1 SV=3" 6 3017.4 - 699019 - - - 3.1826 - 2.306 0.336 - 133.1 1 2 0 0.0072 18 0 0 0 2.52E+07 1.59E+07 - - - 2.4348 1 221125_WJC_METTL3_EV_vs_WT_F07.18278.18278.4 5.38E-09 23/138 R.LHQEYVPSAHLSGTC[160.03]TC[160.03]LAWAPAR.L sp|Q15061|WDR43_HUMAN 1 2724.2901 1.33 104451 18278 4 2724.290082 682.0798 WD repeat-containing protein 43 OS=Homo sapiens OX=9606 GN=WDR43 PE=1 SV=3 6.9 3017.6 - 687220 - - - 0.0026 - 3.408 0.63 - 309.3 1 2 0 0 24 0 0 0 1.73E+07 1.30E+07 - - - 5.1031 0.999 221125_WJC_METTL3_EV_vs_WT_F07.18279.18279.4 0.0557 14/102 R.QEFAQHANAFHQWIQETR.T "sp|Q13813|SPTN1_HUMAN,tr|A0A0D9SF54|A0A0D9SF54_HUMAN,tr|A0A0D9SGF6|A0A0D9SGF6_HUMAN" 3 2240.0511 1.43 104452 18279 4 2240.048179 561.0201 "Spectrin alpha chain, non-erythrocytic 1 OS=Homo sapiens OX=9606 GN=SPTAN1 PE=1 SV=3" 6 3017.7 - 1.14E+06 - - - -1.3254 - 2.472 0.289 - 161.9 1 2 0 -0.003 18 0 0 0 2.66E+07 1.85E+07 - - - 2.0507 1 221125_WJC_METTL3_EV_vs_WT_F07.18280.18280.4 1.25E-12 24/138 R.LHQEYVPSAHLSGTC[160.03]TC[160.03]LAWAPAR[166.11].L sp|Q15061|WDR43_HUMAN 1 2734.2983 1.33 104453 18280 4 2734.299497 684.5819 WD repeat-containing protein 43 OS=Homo sapiens OX=9606 GN=WDR43 PE=1 SV=3 6.9 3017.8 - 714790 - - - 0.4213 - 3.999 0.624 - 284.6 1 2 0 0.0012 24 0 0 0 1.73E+07 1.30E+07 - - - 5.1019 1 221125_WJC_METTL3_EV_vs_WT_F07.18284.18284.3 1.61E-05 15/64 R.RAYFDLQTHVIQVPQGK.Y "sp|Q8WUB8|PHF10_HUMAN,tr|S5FZ81|S5FZ81_HUMAN" 2 1999.0639 0.82 104455 18284 3 1999.066611 667.3619 PHD finger protein 10 OS=Homo sapiens OX=9606 GN=PHF10 PE=1 SV=3 8.6 3018.3 - 357728 - - - 1.3336 - 3.347 0.533 - 279.3 1 2 0 0.0027 17 0 0 0 4.70E+06 5.76E+06 - - - 7.5336 0.9998 221125_WJC_METTL3_EV_vs_WT_F07.18285.18285.4 3.92E-06 21/114 K.ARPFPDGLAEDIDKGEVSAR.Q sp|P13639|EF2_HUMAN 1 2142.0705 0.5 104456 18285 4 2142.074551 536.5249 Elongation factor 2 OS=Homo sapiens OX=9606 GN=EEF2 PE=1 SV=4 4.44 3018.5 - 695109 - - - 1.8697 - 3.047 0.51 - 271 1 2 1 0.004 20 0 0 0 1.02E+07 2.03E+07 - - - 4.0364 1 221125_WJC_METTL3_EV_vs_WT_F07.18289.18289.3 3.03E-12 20/72 K.SKELTTEIDNNIEQISSYK.S "sp|P13645|K1C10_HUMAN,tr|A0A1B0GVI3|A0A1B0GVI3_HUMAN" 2 2211.0907 78.9 104458 18289 3 2211.08866 738.0375 "Keratin, type I cytoskeletal 10 OS=Homo sapiens OX=9606 GN=KRT10 PE=1 SV=6" 4.41 3019 - 1.65E+06 - - - -0.9104 - 3.849 0.601 - 418.7 1 2 1 -0.002 19 0 0 0 2.59E+08 3.29E+06 - - - 8.5513 1 221125_WJC_METTL3_EV_vs_WT_F07.18290.18290.4 5.08E-09 20/132 R.YHVPVVVVPEGSASDTHEQAILR.L "sp|P04844|RPN2_HUMAN,tr|Q5JYR7|Q5JYR7_HUMAN,tr|Q5JYR4|Q5JYR4_HUMAN" 3 2502.2867 1.53 104459 18290 4 2502.285406 626.5789 Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit 2 OS=Homo sapiens OX=9606 GN=RPN2 PE=1 SV=3 5.27 3019.1 - 797802 - - - -0.5119 - 4.113 0.591 - 306 1 2 0 -0.0013 23 0 0 0 1.58E+07 1.04E+07 - - - 4.8279 1 221125_WJC_METTL3_EV_vs_WT_F07.18292.18292.4 2.63E-11 30/144 K.LLEAHEEQNVDSYTESVKEYDSISR.L "sp|P54920|SNAA_HUMAN,tr|M0R213|M0R213_HUMAN,tr|M0R0Y2|M0R0Y2_HUMAN" 3 2940.3625 1.34 104461 18292 4 2940.360021 736.0979 Alpha-soluble NSF attachment protein OS=Homo sapiens OX=9606 GN=NAPA PE=1 SV=3 4.25 3019.3 - 1.67E+06 - - - -0.84 - 5.147 0.686 - 653.7 1 2 1 -0.0025 25 0 0 0 2.00E+07 1.50E+07 - - - 5.7175 0.9998 221125_WJC_METTL3_EV_vs_WT_F07.18293.18293.4 0.00362 Sep-78 K.HWPFMVVNDAGRPK.V "sp|P11142|HSP7C_HUMAN,tr|E9PQQ4|E9PQQ4_HUMAN,tr|E9PNE6|E9PNE6_HUMAN,tr|E9PKE3|E9PKE3_HUMAN,tr|E9PN89|E9PN89_HUMAN,tr|E9PLF4|E9PLF4_HUMAN,tr|E9PK54|E9PK54_HUMAN,tr|E9PN25|E9PN25_HUMAN,tr|E9PPY6|E9PPY6_HUMAN,tr|E9PQK7|E9PQK7_HUMAN" 10 1652.8246 0.13 104462 18293 4 1652.824345 414.2134 Heat shock cognate 71 kDa protein OS=Homo sapiens OX=9606 GN=HSPA8 PE=1 SV=1 8.75 3019.4 - 177030 - - - -0.1337 - 1.739 0.376 - 71.2 1 2 0 -0.0002 14 0 0 0 4.21E+06 3.22E+07 - - - 2.7 1 221125_WJC_METTL3_EV_vs_WT_F07.18302.18302.4 9.59E-08 18/132 R.YHVPVVVVPEGSASDTHEQAILR[166.11].L "sp|P04844|RPN2_HUMAN,tr|Q5JYR7|Q5JYR7_HUMAN,tr|Q5JYR4|Q5JYR4_HUMAN" 3 2512.295 1.53 104466 18302 4 2512.292116 629.081 Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit 2 OS=Homo sapiens OX=9606 GN=RPN2 PE=1 SV=3 5.27 3020.7 - 403224 - - - -1.1308 - 3.231 0.506 - 224.5 1 2 0 -0.0028 23 0 0 0 1.58E+07 1.04E+07 - - - 4.0094 1 221125_WJC_METTL3_EV_vs_WT_F07.18309.18309.4 1.71E-07 24/138 R.GR[166.11]GPPPSWASEPER[166.11]PSILSASELK[136.11].E "sp|Q9Y520|PRC2C_HUMAN,tr|A0A0A0MS30|A0A0A0MS30_HUMAN,tr|E7EPN9|E7EPN9_HUMAN" 3 2575.3389 1.95 104471 18309 4 2575.342837 644.842 Protein PRRC2C OS=Homo sapiens OX=9606 GN=PRRC2C PE=1 SV=4 6.23 3021.6 - 580961 - - - 1.5322 - 4.645 0.615 - 364.6 1 2 1 0.0039 24 0 0 0 1.34E+07 6.88E+06 - - - 5.0708 0.9997 221125_WJC_METTL3_EV_vs_WT_F07.18312.18312.3 0.000636 21/88 K.EDK[136.11]GTGVVTSVPSDSPDDIAALR[166.11].D "sp|Q9P2J5|SYLC_HUMAN,tr|A0A6I8PIV1|A0A6I8PIV1_HUMAN,tr|A0A6I8PRS0|A0A6I8PRS0_HUMAN,tr|A0A6I8PLB8|A0A6I8PLB8_HUMAN,tr|A0A6I8PIP7|A0A6I8PIP7_HUMAN,tr|A0A6I8PIT3|A0A6I8PIT3_HUMAN,tr|A0A6I8PTV8|A0A6I8PTV8_HUMAN,tr|A0A6I8PRU9|A0A6I8PRU9_HUMAN,tr|A0A6I8PLB3|A0A6I8PLB3_HUMAN,tr|A0A6I8PS05|A0A6I8PS05_HUMAN,tr|B4DER1|B4DER1_HUMAN,tr|A0A6I8PL42|A0A6I8PL42_HUMAN" 12 2346.167 2.25 104473 18312 3 2346.172796 783.0629 "Leucine--tRNA ligase, cytoplasmic OS=Homo sapiens OX=9606 GN=LARS1 PE=1 SV=2" 4.04 3021.9 - 739988 - - - 2.4836 - 3.654 0.477 - 361.5 1 2 1 0.0058 23 0 0 0 2.93E+07 1.30E+07 - - - 6.8964 1 221125_WJC_METTL3_EV_vs_WT_F07.18313.18313.3 1.39E-05 15/84 K.QDQPIDFSEDARPSPC[160.03]YQLAQR.T sp|Q96DV4|RM38_HUMAN 1 2620.1976 2.03 104474 18313 3 2620.195838 874.4065 "39S ribosomal protein L38, mitochondrial OS=Homo sapiens OX=9606 GN=MRPL38 PE=1 SV=2" 4.23 3022.1 - 856005 - - - -0.6778 - 2.574 0.489 - 155.9 1 2 0 -0.0018 22 0 0 0 1.57E+07 7.77E+06 - - - 6.2329 0.9998 221125_WJC_METTL3_EV_vs_WT_F07.18316.18316.4 0.000167 13/108 K.GEHSIVYLK[136.11]PSYAFGSVGK[136.11].E sp|Q02790|FKBP4_HUMAN 1 2054.0808 1.01 104477 18316 4 2054.082035 514.5275 Peptidyl-prolyl cis-trans isomerase FKBP4 OS=Homo sapiens OX=9606 GN=FKBP4 PE=1 SV=3 8.44 3022.4 - 335227 - - - 0.6124 - 2.418 0.384 - 155 1 2 0 0.0013 19 0 0 0 2.96E+06 2.92E+06 - - - 2.8667 1 221125_WJC_METTL3_EV_vs_WT_F07.18319.18319.3 1.37E-12 32/124 R.LQAALDDEEAGGRPAMEPGNGSLDLGGDSAGR.S "sp|Q00839|HNRPU_HUMAN,tr|A0A1W2PPS1|A0A1W2PPS1_HUMAN,tr|A0A1X7SBS1|A0A1X7SBS1_HUMAN" 3 3125.432 1.71 104478 18319 3 3125.434588 1042.8179 Heterogeneous nuclear ribonucleoprotein U OS=Homo sapiens OX=9606 GN=HNRNPU PE=1 SV=6 3.9 3022.9 - 1.58E+06 - - - 0.8332 - 5.314 0.749 - 910.5 1 2 0 0.0026 32 0 0 0 2.39E+09 1.40E+09 - - - 10.7327 1 221125_WJC_METTL3_EV_vs_WT_F07.18321.18321.4 1.48E-07 26/138 K.K[136.11]AELLDNEK[136.11]PAAVVAPITTGYTVK[136.11].L sp|Q9HB71|CYBP_HUMAN 1 2551.4324 0.56 104480 18321 4 2551.433014 638.8654 Calcyclin-binding protein OS=Homo sapiens OX=9606 GN=CACYBP PE=1 SV=2 6.18 3023.1 - 1.22E+06 - - - 0.2583 - 3.539 0.561 - 397.3 1 2 0 0.0007 24 0 0 0 5.00E+07 8.93E+07 - - - 4.5144 0.9995 221125_WJC_METTL3_EV_vs_WT_F07.18322.18322.4 1.04E-08 19/150 R.VGYYVNNEYTETELRENPPVKPDFSK.L sp|Q9Y294|ASF1A_HUMAN 1 3087.4825 0.65 104481 18322 4 3087.474853 772.8779 Histone chaperone ASF1A OS=Homo sapiens OX=9606 GN=ASF1A PE=1 SV=1 4.59 3023.2 - 1.01E+06 - - - -2.4917 - 3.536 0.446 - 232 1 2 1 -0.0077 26 0 0 0 8.07E+06 1.24E+07 - - - 3.5042 1 221125_WJC_METTL3_EV_vs_WT_F07.18326.18326.4 6.76E-10 23/138 K.KAELLDNEKPAAVVAPITTGYTVK.L sp|Q9HB71|CYBP_HUMAN 1 2527.3898 0.56 104485 18326 4 2527.394555 632.8547 Calcyclin-binding protein OS=Homo sapiens OX=9606 GN=CACYBP PE=1 SV=2 6.18 3023.7 - 491167 - - - 1.8992 - 3.97 0.599 - 381 1 2 0 0.0048 24 0 0 0 5.00E+07 8.94E+07 - - - 4.8809 0.9999 221125_WJC_METTL3_EV_vs_WT_F07.18327.18327.4 1.90E-07 20/228 R.IFPPETSASVAATPPPSTASAPAAVNSSASADK[136.11]PLSNMK[136.11].L "sp|P09874|PARP1_HUMAN,tr|A0A7I2V3E1|A0A7I2V3E1_HUMAN" 2 3782.9008 1.62 104486 18327 4 3782.896582 946.7325 Poly [ADP-ribose] polymerase 1 OS=Homo sapiens OX=9606 GN=PARP1 PE=1 SV=4 6.07 3023.9 - 329482 - - - -1.1074 - 3.889 0.44 - 99.3 1 2 0 -0.0042 39 0 0 0 1.10E+07 6.83E+06 - - - 3.4486 1 221125_WJC_METTL3_EV_vs_WT_F07.18330.18330.3 1.45E-09 33/76 K.AR[166.11]PFPDGLAEDIDK[136.11]GEVSAR[166.11].Q sp|P13639|EF2_HUMAN 1 2170.1013 0.55 104487 18330 3 2170.101219 724.3744 Elongation factor 2 OS=Homo sapiens OX=9606 GN=EEF2 PE=1 SV=4 4.44 3024.3 - 969343 - - - -0.0309 - 5.531 0.66 - 1515.2 1 2 1 -0.0001 20 0 0 0 5.95E+07 1.07E+08 - - - 10.0477 1 221125_WJC_METTL3_EV_vs_WT_F07.18331.18331.3 1.90E-13 26/92 K.K[136.11]AELLDNEK[136.11]PAAVVAPITTGYTVK[136.11].L sp|Q9HB71|CYBP_HUMAN 1 2551.4324 0.48 104488 18331 3 2551.435856 851.4847 Calcyclin-binding protein OS=Homo sapiens OX=9606 GN=CACYBP PE=1 SV=2 6.18 3024.4 - 1.07E+06 - - - 1.3722 - 4.675 0.618 - 560.3 1 2 0 0.0035 24 0 0 0 1.22E+07 2.53E+07 - - - 9.0111 1 221125_WJC_METTL3_EV_vs_WT_F07.18332.18332.4 2.91E-10 23/186 R.LQAALDDEEAGGRPAMEPGNGSLDLGGDSAGR.S "sp|Q00839|HNRPU_HUMAN,tr|A0A1W2PPS1|A0A1W2PPS1_HUMAN,tr|A0A1X7SBS1|A0A1X7SBS1_HUMAN" 3 3125.432 1.15 104489 18332 4 3125.433219 782.3653 Heterogeneous nuclear ribonucleoprotein U OS=Homo sapiens OX=9606 GN=HNRNPU PE=1 SV=6 3.9 3024.4 - 2.30E+06 - - - 0.3951 - 3.725 0.646 - 186.5 1 2 0 0.0012 32 0 0 0 5.58E+08 4.86E+08 - - - 5.2455 0.9999 221125_WJC_METTL3_EV_vs_WT_F07.18335.18335.4 0.000645 26/114 R.DSDK[136.11]R[166.11]PSLGLAPGGLAVVGR[166.11].S "sp|O95785|WIZ_HUMAN,tr|A0A669KBG4|A0A669KBG4_HUMAN,tr|A0A2R8YFV2|A0A2R8YFV2_HUMAN,tr|A0A669KAV7|A0A669KAV7_HUMAN,tr|M0QXA7|M0QXA7_HUMAN,tr|A0A669KBH9|A0A669KBH9_HUMAN,tr|B9EGQ5|B9EGQ5_HUMAN" 7 1992.1111 1.23 104492 18335 4 1992.113296 499.035 Protein Wiz OS=Homo sapiens OX=9606 GN=WIZ PE=1 SV=2 8.75 3024.8 - 711803 - - - 1.1209 - 3.815 0.486 - 533.2 1 2 1 0.0022 20 0 0 0 9.70E+07 7.90E+07 - - - 3.9032 0.9199 221125_WJC_METTL3_EV_vs_WT_F07.18336.18336.4 0.00554 13/180 D.SPVPTAPTSGGPK[136.11]PSTASAVPELATDPELEK[136.11].K "sp|Q86U44|MTA70_HUMAN,tr|B4E349|B4E349_HUMAN,tr|F5H6D8|F5H6D8_HUMAN,tr|B4DTN4|B4DTN4_HUMAN" 4 3046.5681 0.001 104493 18336 4 3046.56862 762.6493 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 4.41 3025 - 602990 - - - 0.1618 - 2.404 0.31 - 61.2 1 1 0 0.0005 31 0 0 0 0.00E+00 1.20E+08 - - - 2.1907 1 221125_WJC_METTL3_EV_vs_WT_F07.18339.18339.4 9.89E-08 17/90 K.RGFGFVYFQNHDAADK.A sp|Q13151|ROA0_HUMAN 1 1870.8751 1.46 104496 18339 4 1870.875509 468.726 Heterogeneous nuclear ribonucleoprotein A0 OS=Homo sapiens OX=9606 GN=HNRNPA0 PE=1 SV=1 6.75 3025.4 - 387368 - - - 0.2288 - 2.447 0.551 - 187.5 1 2 0 0.0004 16 0 0 0 4.22E+06 2.90E+06 - - - 4.337 1 221125_WJC_METTL3_EV_vs_WT_F07.18340.18340.3 3.61E-10 15/68 K.K[136.11]FYPLEIDYGQDEEAVK[136.11]K[136.11].L sp|P09874|PARP1_HUMAN 1 2195.1213 1.46 104497 18340 3 2195.122732 732.7144 Poly [ADP-ribose] polymerase 1 OS=Homo sapiens OX=9606 GN=PARP1 PE=1 SV=4 4.51 3025.5 - 303650 - - - 0.6747 - 3.368 0.578 - 204.1 1 2 0 0.0015 18 0 0 0 8.26E+07 5.65E+07 - - - 8.0075 1 221125_WJC_METTL3_EV_vs_WT_F07.18341.18341.3 3.06E-09 19/64 K.HSNSNSVDDTIVALNMR[166.11].A "sp|P52948|NUP98_HUMAN,tr|A0A3B3ITD8|A0A3B3ITD8_HUMAN" 2 1881.8878 2.24 104498 18341 3 1881.882404 628.3032 Nuclear pore complex protein Nup98-Nup96 OS=Homo sapiens OX=9606 GN=NUP98 PE=1 SV=4 5.21 3025.6 - 298005 - - - -2.8907 - 2.652 0.605 - 231.1 1 2 0 -0.0054 17 0 0 0 1.34E+08 5.99E+07 - - - 7.7476 0.9975 221125_WJC_METTL3_EV_vs_WT_F07.18342.18342.2 0.0127 12-Jun R.MTLDDFR.L "sp|P35527|K1C9_HUMAN,tr|K7EQQ3|K7EQQ3_HUMAN" 2 896.4062 0.06 104499 18342 2 896.406555 449.2104 "Keratin, type I cytoskeletal 9 OS=Homo sapiens OX=9606 GN=KRT9 PE=1 SV=3" 4.21 3025.7 - 125004 - - - 0.3927 - 1.485 0.204 - 143.9 2 2 0 0.0004 7 0 0 0 4.02E+06 6.81E+07 - - - 1.6661 0.9998 221125_WJC_METTL3_EV_vs_WT_F07.18346.18346.4 0.0405 22/114 R.DSDKRPSLGLAPGGLAVVGR.S "sp|O95785|WIZ_HUMAN,tr|A0A669KBG4|A0A669KBG4_HUMAN,tr|A0A2R8YFV2|A0A2R8YFV2_HUMAN,tr|A0A669KAV7|A0A669KAV7_HUMAN,tr|M0QXA7|M0QXA7_HUMAN,tr|A0A669KBH9|A0A669KBH9_HUMAN,tr|B9EGQ5|B9EGQ5_HUMAN" 7 1964.0803 1.23 104501 18346 4 1964.080263 492.0274 Protein Wiz OS=Homo sapiens OX=9606 GN=WIZ PE=1 SV=2 8.75 3026.2 - 3.02E+06 - - - -0.0305 - 3.294 0.469 - 319.7 1 2 1 -0.0001 20 0 0 0 9.70E+07 7.87E+07 - - - 3.7067 0.9999 221125_WJC_METTL3_EV_vs_WT_F07.18348.18348.3 3.82E-09 25/76 R.DSDK[136.11]R[166.11]PSLGLAPGGLAVVGR[166.11].S "sp|O95785|WIZ_HUMAN,tr|A0A669KBG4|A0A669KBG4_HUMAN,tr|A0A2R8YFV2|A0A2R8YFV2_HUMAN,tr|A0A669KAV7|A0A669KAV7_HUMAN,tr|M0QXA7|M0QXA7_HUMAN,tr|A0A669KBH9|A0A669KBH9_HUMAN,tr|B9EGQ5|B9EGQ5_HUMAN" 7 1992.1111 1.5 104503 18348 3 1992.107549 665.0443 Protein Wiz OS=Homo sapiens OX=9606 GN=WIZ PE=1 SV=2 8.75 3026.5 - 1.98E+06 - - - -1.764 - 3.686 0.484 - 623.6 1 2 1 -0.0035 20 0 0 0 8.09E+07 5.38E+07 - - - 7.1 1 221125_WJC_METTL3_EV_vs_WT_F07.18349.18349.3 1.25E-11 19/64 K.HSNSNSVDDTIVALNMR.A "sp|P52948|NUP98_HUMAN,tr|A0A3B3ITD8|A0A3B3ITD8_HUMAN" 2 1871.8796 2.25 104504 18349 3 1871.8795 624.9671 Nuclear pore complex protein Nup98-Nup96 OS=Homo sapiens OX=9606 GN=NUP98 PE=1 SV=4 5.21 3026.5 - 1.79E+06 - - - -0.0395 - 3.586 0.683 - 462.9 1 2 0 -0.0001 17 0 0 0 1.35E+08 6.00E+07 - - - 9.3809 1 221125_WJC_METTL3_EV_vs_WT_F07.18350.18350.4 2.52E-11 21/102 K.K[136.11]FYPLEIDYGQDEEAVK[136.11]K[136.11].L sp|P09874|PARP1_HUMAN 1 2195.1213 1.88 104505 18350 4 2195.118616 549.7876 Poly [ADP-ribose] polymerase 1 OS=Homo sapiens OX=9606 GN=PARP1 PE=1 SV=4 4.51 3026.6 - 1.52E+06 - - - -1.2004 - 3.691 0.659 - 497.6 1 2 0 -0.0026 18 0 0 0 1.67E+08 8.84E+07 - - - 5.4085 1 221125_WJC_METTL3_EV_vs_WT_F07.18351.18351.3 1.25E-12 27/84 K.R[166.11]GTGGVDTAAVGGVFDVSNADR[166.11].L "sp|P12277|KCRB_HUMAN,tr|H0YJG0|H0YJG0_HUMAN" 2 2140.0412 0.95 104506 18351 3 2140.040574 714.3543 Creatine kinase B-type OS=Homo sapiens OX=9606 GN=CKB PE=1 SV=1 4.43 3026.7 - 1.42E+06 - - - -0.2921 - 4.656 0.669 - 974.4 1 2 0 -0.0006 22 0 0 0 2.85E+07 3.01E+07 - - - 9.6452 1 221125_WJC_METTL3_EV_vs_WT_F07.18352.18352.3 1.94E-18 21/100 K.VDKGVVPLAGTNGETTTQGLDGLSER.C "sp|P04075|ALDOA_HUMAN,tr|H3BR04|H3BR04_HUMAN,tr|H3BMQ8|H3BMQ8_HUMAN,tr|H3BU78|H3BU78_HUMAN,tr|H3BQN4|H3BQN4_HUMAN,tr|H3BUH7|H3BUH7_HUMAN,tr|J3KPS3|J3KPS3_HUMAN,tr|H3BPS8|H3BPS8_HUMAN" 8 2613.3246 1.88 104507 18352 3 2613.324524 872.1155 Fructose-bisphosphate aldolase A OS=Homo sapiens OX=9606 GN=ALDOA PE=1 SV=2 4.32 3026.8 - 964233 - - - -0.0249 - 4.265 0.711 - 435.9 1 2 1 -0.0001 26 0 0 0 2.92E+07 1.55E+07 - - - 9.8039 0.9992 221125_WJC_METTL3_EV_vs_WT_F07.18356.18356.2 1.94E-05 14/28 R.GALQNIIPASTGAAK[136.11].A "sp|P04406|G3P_HUMAN,tr|E7EUT5|E7EUT5_HUMAN" 2 1418.7973 1.31 104509 18356 2 1418.791765 710.4059 Glyceraldehyde-3-phosphate dehydrogenase OS=Homo sapiens OX=9606 GN=GAPDH PE=1 SV=3 8.75 3027.4 - 603882 - - - -3.8857 - 2.862 0.496 - 466.6 1 2 0 -0.0055 15 0 0 0 2.55E+07 1.95E+07 - - - 5.2879 1 221125_WJC_METTL3_EV_vs_WT_F07.18360.18360.3 3.39E-12 24/80 R.QLFHPEQLITGK[136.11]EDAANNYAR[166.11].G "sp|Q9NY65|TBA8_HUMAN,sp|P0DPH7|TBA3C_HUMAN,sp|Q71U36|TBA1A_HUMAN,sp|P0DPH8|TBA3D_HUMAN,sp|P68366|TBA4A_HUMAN,sp|P68363|TBA1B_HUMAN,sp|Q9BQE3|TBA1C_HUMAN,tr|C9JJQ8|C9JJQ8_HUMAN,tr|F8VS66|F8VS66_HUMAN,tr|F8VWV9|F8VWV9_HUMAN,tr|F8VRZ4|F8VRZ4_HUMAN,tr|F8VVB9|F8VVB9_HUMAN,tr|C9JQ00|C9JQ00_HUMAN,tr|C9JEV8|C9JEV8_HUMAN,tr|A0A7P0TA31|A0A7P0TA31_HUMAN,tr|A0A1W2PQM2|A0A1W2PQM2_HUMAN,tr|F5H5D3|F5H5D3_HUMAN,tr|C9J2C0|C9J2C0_HUMAN,tr|C9K0S6|C9K0S6_HUMAN,tr|C9JDL2|C9JDL2_HUMAN,tr|F8VQQ4|F8VQQ4_HUMAN,tr|F8VX09|F8VX09_HUMAN,tr|A0A7P0T945|A0A7P0T945_HUMAN" 23 2432.2203 0.58 104513 18360 3 2432.211076 811.7474 Tubulin alpha-8 chain OS=Homo sapiens OX=9606 GN=TUBA8 PE=1 SV=1 5.45 3027.7 - 1.76E+06 - - - -3.8097 - 4.114 0.631 - 755.2 1 2 1 -0.0093 21 0 0 0 1.52E+08 2.63E+08 - - - 8.9634 0.962 221125_WJC_METTL3_EV_vs_WT_F07.18361.18361.2 1.84E-06 Dec-54 R.SDSPVPTAPTSGGPK[136.11]PSTASAVPELATD.P "sp|Q86U44|MTA70_HUMAN,tr|B4E349|B4E349_HUMAN,tr|F5H6D8|F5H6D8_HUMAN,tr|B4DTN4|B4DTN4_HUMAN" 4 2644.2959 0.001 104514 18361 2 2644.286866 1323.1552 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 4.27 3027.8 - 630544 - - - -3.4244 - 2.147 0.563 - 143.3 1 1 0 -0.0091 28 0 0 0 0.00E+00 6.52E+06 - - - 5.075 0.9999 221125_WJC_METTL3_EV_vs_WT_F07.18364.18364.4 0.000838 19/114 R.AHLSENELEALEKNDMEQMK.Y sp|P98175|RBM10_HUMAN 1 2358.0832 4.16 104515 18364 4 2358.078822 590.5281 RNA-binding protein 10 OS=Homo sapiens OX=9606 GN=RBM10 PE=1 SV=3 4.41 3028.2 - 1.85E+06 - - - -1.8401 - 4.591 0.588 - 337 1 2 1 -0.0043 20 0 0 0 3.63E+07 8.72E+06 - - - 4.8523 1 221125_WJC_METTL3_EV_vs_WT_F07.18373.18373.3 9.15E-13 23/100 K.VDK[136.11]GVVPLAGTNGETTTQGLDGLSER[166.11].C "sp|P04075|ALDOA_HUMAN,tr|H3BR04|H3BR04_HUMAN,tr|H3BMQ8|H3BMQ8_HUMAN,tr|H3BU78|H3BU78_HUMAN,tr|H3BQN4|H3BQN4_HUMAN,tr|H3BUH7|H3BUH7_HUMAN,tr|J3KPS3|J3KPS3_HUMAN,tr|H3BPS8|H3BPS8_HUMAN" 8 2631.3471 1.88 104521 18373 3 2631.34548 878.123 Fructose-bisphosphate aldolase A OS=Homo sapiens OX=9606 GN=ALDOA PE=1 SV=2 4.32 3029.4 - 1.15E+06 - - - -0.6001 - 4.158 0.599 - 504.2 1 2 1 -0.0016 26 0 0 0 2.92E+07 1.55E+07 - - - 8.4963 1 221125_WJC_METTL3_EV_vs_WT_F07.18375.18375.2 2.07E-09 16/62 R.LQAALDDEEAGGRPAMEPGNGSLDLGGDSAGR.S "sp|Q00839|HNRPU_HUMAN,tr|A0A1W2PPS1|A0A1W2PPS1_HUMAN,tr|A0A1X7SBS1|A0A1X7SBS1_HUMAN" 3 3125.432 2.26 104523 18375 2 3125.426872 1563.7233 Heterogeneous nuclear ribonucleoprotein U OS=Homo sapiens OX=9606 GN=HNRNPU PE=1 SV=6 3.9 3029.7 - 1.87E+06 - - - -1.6356 - 2.383 0.685 - 91.9 1 2 0 -0.0051 32 0 0 0 1.29E+07 5.68E+06 - - - 6.2337 0.9999 221125_WJC_METTL3_EV_vs_WT_F07.18382.18382.2 1.10E-06 16/28 R.GALQNIIPASTGAAK.A "sp|P04406|G3P_HUMAN,tr|E7EUT5|E7EUT5_HUMAN" 2 1410.7831 1.22 104527 18382 2 1410.781999 706.3988 Glyceraldehyde-3-phosphate dehydrogenase OS=Homo sapiens OX=9606 GN=GAPDH PE=1 SV=3 8.75 3030.6 - 965722 - - - -0.7648 - 2.618 0.518 - 698.1 1 2 0 -0.0011 15 0 0 0 3.17E+07 2.61E+07 - - - 5.2327 1 221125_WJC_METTL3_EV_vs_WT_F07.18383.18383.3 1.04E-11 27/80 R.QLFHPEQLITGKEDAANNYAR.G "sp|Q9NY65|TBA8_HUMAN,sp|P0DPH7|TBA3C_HUMAN,sp|Q71U36|TBA1A_HUMAN,sp|P0DPH8|TBA3D_HUMAN,sp|P68366|TBA4A_HUMAN,sp|P68363|TBA1B_HUMAN,sp|Q9BQE3|TBA1C_HUMAN,tr|C9JJQ8|C9JJQ8_HUMAN,tr|F8VS66|F8VS66_HUMAN,tr|F8VWV9|F8VWV9_HUMAN,tr|F8VRZ4|F8VRZ4_HUMAN,tr|F8VVB9|F8VVB9_HUMAN,tr|C9JQ00|C9JQ00_HUMAN,tr|C9JEV8|C9JEV8_HUMAN,tr|A0A7P0TA31|A0A7P0TA31_HUMAN,tr|A0A1W2PQM2|A0A1W2PQM2_HUMAN,tr|F5H5D3|F5H5D3_HUMAN,tr|C9J2C0|C9J2C0_HUMAN,tr|C9K0S6|C9K0S6_HUMAN,tr|C9JDL2|C9JDL2_HUMAN,tr|F8VQQ4|F8VQQ4_HUMAN,tr|F8VX09|F8VX09_HUMAN,tr|A0A7P0T945|A0A7P0T945_HUMAN" 23 2414.1979 0.58 104528 18383 3 2414.191107 805.7399 Tubulin alpha-8 chain OS=Homo sapiens OX=9606 GN=TUBA8 PE=1 SV=1 5.45 3030.7 - 2.80E+06 - - - -2.8022 - 4.541 0.649 - 1106.6 1 2 1 -0.0068 21 0 0 0 1.52E+08 2.63E+08 - - - 9.4015 0.9999 221125_WJC_METTL3_EV_vs_WT_F07.18387.18387.4 2.02E-07 24/108 K.LQHDLSWTPYEDIEKQDAK.L sp|Q9BV19|CA050_HUMAN 1 2315.107 1.63 104530 18387 4 2315.104172 579.784 Uncharacterized protein C1orf50 OS=Homo sapiens OX=9606 GN=C1orf50 PE=1 SV=2 4.43 3031.2 - 897933 - - - -1.2177 - 4.106 0.547 - 598.9 1 2 1 -0.0028 19 0 0 0 1.94E+07 1.19E+07 - - - 4.4641 0.9998 221125_WJC_METTL3_EV_vs_WT_F07.18388.18388.4 5.80E-06 13/108 R.GLLQDDAHPTLVTYADHSK[136.11].L "sp|Q86U44|MTA70_HUMAN,tr|F5H6D8|F5H6D8_HUMAN,tr|H0YFV6|H0YFV6_HUMAN,tr|B4DTN4|B4DTN4_HUMAN" 4 2088.0367 0.02 104531 18388 4 2088.03064 523.0165 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 5.13 3031.4 - 755887 - - - -2.9181 - 2.539 0.447 - 160.8 1 2 0 -0.0061 19 0 0 0 4.63E+05 2.94E+07 - - - 3.4302 1 221125_WJC_METTL3_EV_vs_WT_F07.18389.18389.4 6.30E-07 20/108 R.QGYSLSGYYTHPFQGYEHR[166.11].Q "sp|P55265|DSRAD_HUMAN,tr|A2IBT1|A2IBT1_HUMAN,tr|A0A3B3ISU1|A0A3B3ISU1_HUMAN,tr|A0A7P0Z4K3|A0A7P0Z4K3_HUMAN,tr|A0A3B3ISX1|A0A3B3ISX1_HUMAN" 5 2299.0322 1.03 104532 18389 4 2299.026803 575.7653 Double-stranded RNA-specific adenosine deaminase OS=Homo sapiens OX=9606 GN=ADAR PE=1 SV=4 6.92 3031.5 - 799204 - - - -2.3475 - 4.268 0.542 - 280.2 1 2 0 -0.0054 19 0 0 0 2.72E+07 2.65E+07 - - - 4.433 0.9988 221125_WJC_METTL3_EV_vs_WT_F07.18391.18391.3 2.41 17/76 R.DSDKRPSLGLAPGGLAVVGR.S "sp|O95785|WIZ_HUMAN,tr|A0A669KBG4|A0A669KBG4_HUMAN,tr|A0A2R8YFV2|A0A2R8YFV2_HUMAN,tr|A0A669KAV7|A0A669KAV7_HUMAN,tr|M0QXA7|M0QXA7_HUMAN,tr|A0A669KBH9|A0A669KBH9_HUMAN,tr|B9EGQ5|B9EGQ5_HUMAN" 7 1964.0803 1.5 104533 18391 3 1964.077769 655.7007 Protein Wiz OS=Homo sapiens OX=9606 GN=WIZ PE=1 SV=2 8.75 3031.7 - 3.01E+06 - - - -1.3004 - 2.902 0.3 - 254.5 1 2 1 -0.0026 20 0 0 0 8.09E+07 5.38E+07 - - - 4.4687 1 221125_WJC_METTL3_EV_vs_WT_F07.18395.18395.4 2.97E-06 16/108 R.QGYSLSGYYTHPFQGYEHR.Q "sp|P55265|DSRAD_HUMAN,tr|A2IBT1|A2IBT1_HUMAN,tr|A0A3B3ISU1|A0A3B3ISU1_HUMAN,tr|A0A7P0Z4K3|A0A7P0Z4K3_HUMAN,tr|A0A3B3ISX1|A0A3B3ISX1_HUMAN" 5 2289.0239 1.03 104535 18395 4 2289.02348 573.2633 Double-stranded RNA-specific adenosine deaminase OS=Homo sapiens OX=9606 GN=ADAR PE=1 SV=4 6.92 3032.1 - 1.34E+06 - - - -0.1966 - 3.646 0.523 - 150.1 1 2 0 -0.0005 19 0 0 0 2.72E+07 2.65E+07 - - - 4.2157 0.9998 221125_WJC_METTL3_EV_vs_WT_F07.18402.18402.4 0.000422 14/90 K.SKDDAPHELESQFILR.L "sp|Q15545|TAF7_HUMAN,tr|A0A096LPC3|A0A096LPC3_HUMAN" 2 1883.9377 1.64 104540 18402 4 1883.935184 471.9917 Transcription initiation factor TFIID subunit 7 OS=Homo sapiens OX=9606 GN=TAF7 PE=1 SV=1 4.75 3033 - 988055 - - - -1.3573 - 2.663 0.483 - 213.7 1 2 1 -0.0026 16 0 0 0 1.10E+07 6.72E+06 - - - 3.7743 1 221125_WJC_METTL3_EV_vs_WT_F07.18408.18408.4 2.50E-08 17/78 K.HWPFMVVNDAGR[166.11]PK[136.11].V "sp|P11142|HSP7C_HUMAN,tr|E9PQQ4|E9PQQ4_HUMAN,tr|E9PNE6|E9PNE6_HUMAN,tr|E9PKE3|E9PKE3_HUMAN,tr|E9PN89|E9PN89_HUMAN,tr|E9PLF4|E9PLF4_HUMAN,tr|E9PK54|E9PK54_HUMAN,tr|E9PN25|E9PN25_HUMAN,tr|E9PPY6|E9PPY6_HUMAN,tr|E9PQK7|E9PQK7_HUMAN" 10 1670.847 0.16 104544 18408 4 1670.845452 418.719 Heat shock cognate 71 kDa protein OS=Homo sapiens OX=9606 GN=HSPA8 PE=1 SV=1 8.75 3033.8 - 707504 - - - -0.948 - 2.528 0.552 - 288.1 1 2 0 -0.0016 14 0 0 0 4.56E+06 2.83E+07 - - - 4.3677 0.9999 221125_WJC_METTL3_EV_vs_WT_F07.18412.18412.4 8.88E-05 13/78 K.AVDIPHMDIEALKK.L sp|P62906|RL10A_HUMAN 1 1578.844 0.9 104546 18412 4 1578.842133 395.7183 60S ribosomal protein L10a OS=Homo sapiens OX=9606 GN=RPL10A PE=1 SV=2 5.38 3034.3 - 355717 - - - -1.1597 - 1.876 0.472 - 99.3 1 2 0 -0.0018 14 0 0 0 1.50E+07 1.66E+07 - - - 3.5628 0.9999 221125_WJC_METTL3_EV_vs_WT_F07.18413.18413.4 5.11E-08 17/108 K.LQHDLSWTPYEDIEK[136.11]QDAK[136.11].L sp|Q9BV19|CA050_HUMAN 1 2331.1354 1.64 104547 18413 4 2331.136498 583.7911 Uncharacterized protein C1orf50 OS=Homo sapiens OX=9606 GN=C1orf50 PE=1 SV=2 4.43 3034.4 - 573757 - - - 0.4749 - 2.916 0.537 - 213.4 1 2 1 0.0011 19 0 0 0 1.94E+07 1.18E+07 - - - 4.2618 1 221125_WJC_METTL3_EV_vs_WT_F07.18420.18420.3 1.51E-16 22/80 K.NQALNTDNYGHDLASVQALQR.K "sp|Q13813|SPTN1_HUMAN,tr|A0A0D9SF54|A0A0D9SF54_HUMAN,tr|A0A0D9SGF6|A0A0D9SGF6_HUMAN" 3 2327.1254 1.48 104552 18420 3 2327.127774 776.7158 "Spectrin alpha chain, non-erythrocytic 1 OS=Homo sapiens OX=9606 GN=SPTAN1 PE=1 SV=3" 5.21 3035.4 - 1.90E+06 - - - 1.0051 - 4.897 0.705 - 588.2 1 2 0 0.0023 21 0 0 0 1.02E+08 6.89E+07 - - - 10.2081 1 221125_WJC_METTL3_EV_vs_WT_F07.18423.18423.3 1.77E-09 16/52 K.HWPFMVVNDAGR[166.11]PK[136.11].V "sp|P11142|HSP7C_HUMAN,tr|E9PQQ4|E9PQQ4_HUMAN,tr|E9PNE6|E9PNE6_HUMAN,tr|E9PKE3|E9PKE3_HUMAN,tr|E9PN89|E9PN89_HUMAN,tr|E9PLF4|E9PLF4_HUMAN,tr|E9PK54|E9PK54_HUMAN,tr|E9PN25|E9PN25_HUMAN,tr|E9PPY6|E9PPY6_HUMAN,tr|E9PQK7|E9PQK7_HUMAN" 10 1670.847 0.13 104554 18423 3 1670.84924 557.9563 Heat shock cognate 71 kDa protein OS=Homo sapiens OX=9606 GN=HSPA8 PE=1 SV=1 8.75 3035.8 - 1.37E+06 - - - 1.3191 - 3.191 0.569 - 414.5 1 2 0 0.0022 14 0 0 0 1.46E+07 1.11E+08 - - - 7.9668 1 221125_WJC_METTL3_EV_vs_WT_F07.18425.18425.3 9.36E-16 24/80 K.NQALNTDNYGHDLASVQALQR[166.11].K "sp|Q13813|SPTN1_HUMAN,tr|A0A0D9SF54|A0A0D9SF54_HUMAN,tr|A0A0D9SGF6|A0A0D9SGF6_HUMAN" 3 2337.1337 1.48 104555 18425 3 2337.13137 780.0518 "Spectrin alpha chain, non-erythrocytic 1 OS=Homo sapiens OX=9606 GN=SPTAN1 PE=1 SV=3" 5.21 3036 - 1.80E+06 - - - -0.9991 - 4.519 0.73 - 784 1 2 0 -0.0023 21 0 0 0 1.02E+08 6.89E+07 - - - 10.2942 1 221125_WJC_METTL3_EV_vs_WT_F07.18426.18426.4 9.84E-10 25/126 R.GLPVTC[160.03]EVAPHHLFLSHDDLER[166.11].L "sp|P27708|PYR1_HUMAN,tr|F8VPD4|F8VPD4_HUMAN" 2 2551.2517 0.85 104556 18426 4 2551.258193 638.8202 CAD protein OS=Homo sapiens OX=9606 GN=CAD PE=1 SV=3 5.21 3036.1 - 680968 - - - 2.5403 - 4.737 0.572 - 604.7 1 2 0 0.0065 22 0 0 0 1.05E+07 1.23E+07 - - - 4.7118 0.9999 221125_WJC_METTL3_EV_vs_WT_F07.18432.18432.4 3.93E-07 25/120 R.QLFHPEQLITGKEDAANNYAR.G "sp|Q9NY65|TBA8_HUMAN,sp|P0DPH7|TBA3C_HUMAN,sp|Q71U36|TBA1A_HUMAN,sp|P0DPH8|TBA3D_HUMAN,sp|P68366|TBA4A_HUMAN,sp|P68363|TBA1B_HUMAN,sp|Q9BQE3|TBA1C_HUMAN,tr|C9JJQ8|C9JJQ8_HUMAN,tr|F8VS66|F8VS66_HUMAN,tr|F8VWV9|F8VWV9_HUMAN,tr|F8VRZ4|F8VRZ4_HUMAN,tr|F8VVB9|F8VVB9_HUMAN,tr|C9JQ00|C9JQ00_HUMAN,tr|C9JEV8|C9JEV8_HUMAN,tr|A0A7P0TA31|A0A7P0TA31_HUMAN,tr|A0A1W2PQM2|A0A1W2PQM2_HUMAN,tr|F5H5D3|F5H5D3_HUMAN,tr|C9J2C0|C9J2C0_HUMAN,tr|C9K0S6|C9K0S6_HUMAN,tr|C9JDL2|C9JDL2_HUMAN,tr|F8VQQ4|F8VQQ4_HUMAN,tr|F8VX09|F8VX09_HUMAN,tr|A0A7P0T945|A0A7P0T945_HUMAN" 23 2414.1979 0.6 104561 18432 4 2414.201115 604.5567 Tubulin alpha-8 chain OS=Homo sapiens OX=9606 GN=TUBA8 PE=1 SV=1 5.45 3036.9 - 1.74E+07 - - - 1.3433 - 4.275 0.58 - 693.1 1 2 1 0.0032 21 0 0 0 4.61E+08 7.66E+08 - - - 4.7538 1 221125_WJC_METTL3_EV_vs_WT_F07.18434.18434.4 0.000185 13/78 K.AVDIPHMDIEALK[136.11]K[136.11].L sp|P62906|RL10A_HUMAN 1 1594.8724 0.9 104562 18434 4 1594.871448 399.7254 60S ribosomal protein L10a OS=Homo sapiens OX=9606 GN=RPL10A PE=1 SV=2 5.38 3037.1 - 504573 - - - -0.5743 - 2.204 0.516 - 101 1 2 0 -0.0009 14 0 0 0 1.49E+07 1.64E+07 - - - 4.0046 1 221125_WJC_METTL3_EV_vs_WT_F07.18441.18441.3 9.35E-10 18/104 R.PVETTLENNEGGQEQGPSVEGLNVPTK.A "sp|Q9NP61|ARFG3_HUMAN,tr|B0QYV8|B0QYV8_HUMAN,tr|H0Y6A0|H0Y6A0_HUMAN" 3 2822.357 1.78 104567 18441 3 2822.359265 941.7929 ADP-ribosylation factor GTPase-activating protein 3 OS=Homo sapiens OX=9606 GN=ARFGAP3 PE=1 SV=1 3.98 3037.9 - 747367 - - - 0.7986 - 3.652 0.645 - 209.7 1 1 0 0.0023 27 0 0 0 1.36E+07 7.65E+06 - - - 8.7104 1 221125_WJC_METTL3_EV_vs_WT_F07.18445.18445.3 1.43E-10 21/124 R.LQAALDDEEAGGR[166.11]PAMEPGNGSLDLGGDSAGR[166.11].S "sp|Q00839|HNRPU_HUMAN,tr|A0A1W2PPS1|A0A1W2PPS1_HUMAN,tr|A0A1X7SBS1|A0A1X7SBS1_HUMAN" 3 3145.4485 1.71 104569 18445 3 3145.447059 1049.4901 Heterogeneous nuclear ribonucleoprotein U OS=Homo sapiens OX=9606 GN=HNRNPU PE=1 SV=6 3.9 3038.4 - 748292 - - - -0.4658 - 3.922 0.694 - 344.7 1 2 0 -0.0015 32 0 0 0 2.39E+09 1.40E+09 - - - 9.4211 0.9999 221125_WJC_METTL3_EV_vs_WT_F07.18451.18451.3 1.41E-08 14/68 R.K[136.11]PYVLNDLEAEASLPEK[136.11]K[136.11].G "sp|Q9Y3C1|NOP16_HUMAN,tr|A0A0C4DGU5|A0A0C4DGU5_HUMAN,tr|D6RIC3|D6RIC3_HUMAN,tr|A0A087X2G6|A0A087X2G6_HUMAN" 4 2067.1314 0.8 104573 18451 3 2067.124314 690.0511 Nucleolar protein 16 OS=Homo sapiens OX=9606 GN=NOP16 PE=1 SV=2 4.87 3039.2 - 219089 - - - -3.4386 - 2.798 0.559 - 246.9 1 2 0 -0.0071 18 0 0 0 6.80E+06 8.48E+06 - - - 7.3324 1 221125_WJC_METTL3_EV_vs_WT_F07.18452.18452.4 3.81E-06 17/102 R.K[136.11]PYVLNDLEAEASLPEK[136.11]K[136.11].G "sp|Q9Y3C1|NOP16_HUMAN,tr|A0A0C4DGU5|A0A0C4DGU5_HUMAN,tr|D6RIC3|D6RIC3_HUMAN,tr|A0A087X2G6|A0A087X2G6_HUMAN" 4 2067.1314 0.54 104574 18452 4 2067.129309 517.7901 Nucleolar protein 16 OS=Homo sapiens OX=9606 GN=NOP16 PE=1 SV=2 4.87 3039.3 - 324213 - - - -1.0222 - 2.983 0.506 - 209.3 1 2 0 -0.0021 18 0 0 0 4.06E+06 7.46E+06 - - - 4.004 1 221125_WJC_METTL3_EV_vs_WT_F07.18461.18461.4 5.76E-14 26/162 Q.VIILNHPGQISAGYAPVLDC[160.03]HTAHIAC[160.03]K[136.11].F "sp|P68104|EF1A1_HUMAN,tr|A0A7I2V659|A0A7I2V659_HUMAN,tr|A0A7I2V5N4|A0A7I2V5N4_HUMAN,tr|A0A087WVQ9|A0A087WVQ9_HUMAN,tr|A0A087WV01|A0A087WV01_HUMAN" 5 3062.5674 0.32 104581 18461 4 3062.567183 766.6491 Elongation factor 1-alpha 1 OS=Homo sapiens OX=9606 GN=EEF1A1 PE=1 SV=1 6.98 3040.3 - 2.95E+06 - - - -0.0598 - 5.071 0.622 - 340 1 1 0 -0.0002 28 0 0 0 1.69E+07 5.24E+07 - - - 5.1439 1 221125_WJC_METTL3_EV_vs_WT_F07.18464.18464.3 8.93E-09 17/80 K.GNLYSFGC[160.03]PEYGQLGHNSDGK[136.11].F sp|Q9P258|RCC2_HUMAN 1 2307.0106 0.48 104584 18464 3 2307.014652 770.0108 Protein RCC2 OS=Homo sapiens OX=9606 GN=RCC2 PE=1 SV=2 5.32 3040.7 - 419792 - - - 1.7586 - 3.033 0.648 - 251.1 1 2 0 0.0041 21 0 0 0 5.62E+06 1.16E+07 - - - 8.4235 0.9972 221125_WJC_METTL3_EV_vs_WT_F07.18471.18471.4 7.00E-06 24/132 R.SISDAPAPAYHDPLYLEDQVSHR[166.11].R "sp|Q9H6H4|REEP4_HUMAN,tr|E5RGS2|E5RGS2_HUMAN" 2 2590.2328 1.47 104589 18471 4 2590.215176 648.5655 Receptor expression-enhancing protein 4 OS=Homo sapiens OX=9606 GN=REEP4 PE=1 SV=1 4.63 3041.6 - 859128 - - - -6.7851 - 3.555 0.443 - 272.6 1 2 0 -0.0176 23 0 0 0 1.30E+07 8.82E+06 - - - 3.4879 0.9998 221125_WJC_METTL3_EV_vs_WT_F07.18475.18475.4 9.48E-10 19/114 R.TGEADR[166.11]EVSEISIVDIANK[136.11]R[166.11].S "sp|Q14789|GOGB1_HUMAN,tr|E7EU81|E7EU81_HUMAN,tr|H0Y867|H0Y867_HUMAN" 3 2229.1595 1.84 104591 18475 4 2229.159665 558.2972 Golgin subfamily B member 1 OS=Homo sapiens OX=9606 GN=GOLGB1 PE=1 SV=2 4.51 3042.1 - 682904 - - - 0.0606 - 3.342 0.472 - 299.1 1 2 1 0.0001 20 0 0 0 1.45E+07 7.86E+06 - - - 3.7376 0.9999 221125_WJC_METTL3_EV_vs_WT_F07.18476.18476.4 5.72E-08 24/114 R.TGEADREVSEISIVDIANKR.S "sp|Q14789|GOGB1_HUMAN,tr|E7EU81|E7EU81_HUMAN,tr|H0Y867|H0Y867_HUMAN" 3 2201.1288 2.24 104592 18476 4 2201.131823 551.2895 Golgin subfamily B member 1 OS=Homo sapiens OX=9606 GN=GOLGB1 PE=1 SV=2 4.51 3042.2 - 681583 - - - 1.3779 - 3.749 0.554 - 463.3 1 2 1 0.003 20 0 0 0 1.76E+07 7.86E+06 - - - 4.489 0.9794 221125_WJC_METTL3_EV_vs_WT_F07.18479.18479.3 0.00931 Sep-88 R.TTVTELPQTSHVSFSEPDIPSSK[136.11].S "sp|Q9NYP3|DONS_HUMAN,tr|H7C006|H7C006_HUMAN,tr|F8W8A5|F8W8A5_HUMAN,tr|C9J4K5|C9J4K5_HUMAN,tr|C9JSP0|C9JSP0_HUMAN,tr|H7C304|H7C304_HUMAN,tr|F8WD19|F8WD19_HUMAN" 7 2494.2319 0.54 104595 18479 3 2494.243473 832.4179 Protein downstream neighbor of Son OS=Homo sapiens OX=9606 GN=DONSON PE=1 SV=2 4.65 3042.6 - 326876 - - - 4.6543 - 1.767 0.278 - 52.1 1 2 0 0.0116 23 0 0 0 2.54E+06 4.67E+06 - - - 2.9717 0.947 221125_WJC_METTL3_EV_vs_WT_F07.18481.18481.4 0.0865 Sep-90 K.YFLHDDRDDGVDYWAK.R "sp|Q9NYF8|BCLF1_HUMAN,tr|H0YF14|H0YF14_HUMAN" 2 2013.8857 2.97 104597 18481 4 2013.882093 504.4787 Bcl-2-associated transcription factor 1 OS=Homo sapiens OX=9606 GN=BCLAF1 PE=1 SV=2 4.28 3042.9 - 169073 - - - -1.794 - 1.508 0.203 - 41.5 1 2 1 -0.0036 16 0 0 0 3.91E+06 1.32E+06 - - - 1.1366 0.9999 221125_WJC_METTL3_EV_vs_WT_F07.18486.18486.4 5.44E-09 18/144 R.VLRPPGGGSNFSLGFDEPTEQPVRK.N "sp|Q9UK76|JUPI1_HUMAN,tr|J3KT51|J3KT51_HUMAN" 2 2683.3718 1.75 104600 18486 4 2683.383602 671.8502 Jupiter microtubule associated homolog 1 OS=Homo sapiens OX=9606 GN=JPT1 PE=1 SV=3 6.15 3043.5 - 410856 - - - 4.393 - 3.529 0.592 - 167.3 1 2 0 0.0118 25 0 0 0 1.22E+07 6.98E+06 - - - 4.7767 0.9986 221125_WJC_METTL3_EV_vs_WT_F07.18487.18487.3 1.37E-06 15/84 R.KLTATPTPLGGMTGFHMQTEDR.T sp|O75533|SF3B1_HUMAN 1 2388.1566 2.24 104601 18487 3 2389.156808 797.0595 Splicing factor 3B subunit 1 OS=Homo sapiens OX=9606 GN=SF3B1 PE=1 SV=3 6.75 3043.6 - 346265 - - - 418.8197 - 2.65 0.498 - 202.9 1 2 0 1.0002 22 0 0 0 1.59E+07 7.09E+06 - - - 6.1257 0.9999 221125_WJC_METTL3_EV_vs_WT_F07.18489.18489.4 5.46E-05 Nov-96 R.MHTTFEHDIQALGTQVR[166.11].Q "sp|Q01082|SPTB2_HUMAN,tr|A0A087WUZ3|A0A087WUZ3_HUMAN" 2 1992.9715 1.43 104603 18489 4 1992.976136 499.2502 "Spectrin beta chain, non-erythrocytic 1 OS=Homo sapiens OX=9606 GN=SPTBN1 PE=1 SV=2" 5.95 3043.9 - 262939 - - - 2.3192 - 2.182 0.46 - 92.6 1 2 0 0.0046 17 0 0 0 6.20E+06 4.35E+06 - - - 3.4995 0.999 221125_WJC_METTL3_EV_vs_WT_F07.18492.18492.3 0.00287 Jul-88 R.SISDAPAPAYHDPLYLEDQVSHR[166.11].R "sp|Q9H6H4|REEP4_HUMAN,tr|E5RGS2|E5RGS2_HUMAN" 2 2590.2328 0.33 104606 18492 3 2590.225362 864.4182 Receptor expression-enhancing protein 4 OS=Homo sapiens OX=9606 GN=REEP4 PE=1 SV=1 4.63 3044.3 - 151617 - - - -2.8526 - 1.538 0.417 - 23.1 1 2 0 -0.0074 23 0 0 0 2.04E+05 6.15E+05 - - - 4.197 0.9999 221125_WJC_METTL3_EV_vs_WT_F07.18494.18494.3 2.09E-08 16/68 R.KPYVLNDLEAEASLPEKK.G "sp|Q9Y3C1|NOP16_HUMAN,tr|A0A0C4DGU5|A0A0C4DGU5_HUMAN,tr|D6RIC3|D6RIC3_HUMAN,tr|A0A087X2G6|A0A087X2G6_HUMAN" 4 2043.0888 0.79 104607 18494 3 2043.097375 682.0369 Nucleolar protein 16 OS=Homo sapiens OX=9606 GN=NOP16 PE=1 SV=2 4.87 3044.5 - 327697 - - - 4.1863 - 3.375 0.531 - 299 1 2 0 0.0086 18 0 0 0 6.70E+06 8.48E+06 - - - 7.4867 1 221125_WJC_METTL3_EV_vs_WT_F07.18496.18496.4 1.51E-11 21/126 R.KLTATPTPLGGMTGFHMQTEDR.T sp|O75533|SF3B1_HUMAN 1 2388.1566 0.77 104608 18496 4 2388.163871 598.0464 Splicing factor 3B subunit 1 OS=Homo sapiens OX=9606 GN=SF3B1 PE=1 SV=3 6.75 3044.7 - 787223 - - - 3.0442 - 3.686 0.661 - 326.5 1 2 0 0.0073 22 0 0 0 2.01E+07 2.61E+07 - - - 5.4042 0.989 221125_WJC_METTL3_EV_vs_WT_F07.18498.18498.4 0.0978 Dec-72 K.LK[136.11]DLFDYSPPLHK[136.11].N "sp|Q9NYF8|BCLF1_HUMAN,tr|E9PKI6|E9PKI6_HUMAN,tr|A0A1W2PQ43|A0A1W2PQ43_HUMAN,tr|E9PK91|E9PK91_HUMAN,tr|E9PK09|E9PK09_HUMAN,tr|E9PQN2|E9PQN2_HUMAN" 6 1587.8632 2.47 104610 18498 4 1587.864258 397.9731 Bcl-2-associated transcription factor 1 OS=Homo sapiens OX=9606 GN=BCLAF1 PE=1 SV=2 6.75 3045 - 427153 - - - 0.6789 - 1.463 0.261 - 42.6 1 2 1 0.0011 13 0 0 0 6.73E+07 2.73E+07 - - - 1.6385 1 221125_WJC_METTL3_EV_vs_WT_F07.18500.18500.4 2.01E-08 14/96 R.MHTTFEHDIQALGTQVR.Q "sp|Q01082|SPTB2_HUMAN,tr|A0A087WUZ3|A0A087WUZ3_HUMAN" 2 1982.9632 1.3 104612 18500 4 1982.967799 496.7481 "Spectrin beta chain, non-erythrocytic 1 OS=Homo sapiens OX=9606 GN=SPTBN1 PE=1 SV=2" 5.95 3045.3 - 305771 - - - 2.2971 - 2.664 0.568 - 155 1 2 0 0.0046 17 0 0 0 6.37E+06 4.91E+06 - - - 4.5088 0.9969 221125_WJC_METTL3_EV_vs_WT_F07.18502.18502.3 1.02E-08 17/100 R.GSVLNSYSAQPNFGAPASPAGSNPAR.P "tr|B4DHE8|B4DHE8_HUMAN,tr|A0A6Q8PF05|A0A6Q8PF05_HUMAN" 2 2516.2044 2.41 104614 18502 3 2516.211011 839.7421 RNA-binding protein Musashi homolog 2 OS=Homo sapiens OX=9606 GN=MSI2 PE=1 SV=1 8.75 3045.5 - 257914 - - - 2.6218 - 3.458 0.617 - 164.4 1 1 0 0.0066 26 0 0 0 5.77E+06 2.39E+06 - - - 8.2715 1 221125_WJC_METTL3_EV_vs_WT_F07.18507.18507.4 8.82E-11 29/114 K.AR[166.11]PFPDGLAEDIDK[136.11]GEVSAR[166.11].Q sp|P13639|EF2_HUMAN 1 2170.1013 0.53 104617 18507 4 2170.104592 543.5326 Elongation factor 2 OS=Homo sapiens OX=9606 GN=EEF2 PE=1 SV=4 4.44 3046.2 - 5.25E+06 - - - 1.5234 - 4.805 0.626 - 908.4 1 2 1 0.0033 20 0 0 0 1.23E+08 2.32E+08 - - - 5.1986 0.9987 221125_WJC_METTL3_EV_vs_WT_F07.18508.18508.4 0.00124 11/108 R.YK[136.11]VPDGK[136.11]PENEFAFNAEFK[136.11].D sp|Q15181|IPYR_HUMAN 1 2253.1168 0.55 104618 18508 4 2253.121871 564.2865 Inorganic pyrophosphatase OS=Homo sapiens OX=9606 GN=PPA1 PE=1 SV=2 4.87 3046.2 - 795026 - - - 2.2351 - 2.247 0.386 - 82.8 1 2 1 0.005 19 0 0 0 1.33E+07 2.40E+07 - - - 2.8582 1 221125_WJC_METTL3_EV_vs_WT_F07.18509.18509.3 1.91E-12 18/64 R.MHTTFEHDIQALGTQVR[166.11].Q "sp|Q01082|SPTB2_HUMAN,tr|A0A087WUZ3|A0A087WUZ3_HUMAN" 2 1992.9715 0.91 104619 18509 3 1992.973198 665.3311 "Spectrin beta chain, non-erythrocytic 1 OS=Homo sapiens OX=9606 GN=SPTBN1 PE=1 SV=2" 5.95 3046.4 - 724469 - - - 0.845 - 3.351 0.65 - 375.9 1 2 0 0.0017 17 0 0 0 9.11E+06 1.00E+07 - - - 8.8413 0.9995 221125_WJC_METTL3_EV_vs_WT_F07.18512.18512.3 1.45E-09 16/68 R.NHIENQDEC[160.03]VLNVISHAR[166.11].L "sp|Q9BZE1|RM37_HUMAN,tr|S4R369|S4R369_HUMAN" 2 2157.0261 1.21 104622 18512 3 2157.040156 720.016 "39S ribosomal protein L37, mitochondrial OS=Homo sapiens OX=9606 GN=MRPL37 PE=1 SV=2" 5.27 3046.8 - 251914 - - - 6.5308 - 2.993 0.616 - 382.2 1 2 0 0.0141 18 0 0 0 6.45E+06 5.33E+06 - - - 8.1337 1 221125_WJC_METTL3_EV_vs_WT_F07.18516.18516.3 1.65E-12 21/64 R.MHTTFEHDIQALGTQVR.Q "sp|Q01082|SPTB2_HUMAN,tr|A0A087WUZ3|A0A087WUZ3_HUMAN" 2 1982.9632 0.87 104624 18516 3 1982.967532 661.995 "Spectrin beta chain, non-erythrocytic 1 OS=Homo sapiens OX=9606 GN=SPTBN1 PE=1 SV=2" 5.95 3047.3 - 529403 - - - 2.1624 - 3.385 0.649 - 566.5 1 2 0 0.0043 17 0 0 0 8.39E+06 9.63E+06 - - - 8.855 0.9993 221125_WJC_METTL3_EV_vs_WT_F07.18517.18517.3 2.52E-07 Nov-48 K.LKDLFDYSPPLHK.N "sp|Q9NYF8|BCLF1_HUMAN,tr|E9PKI6|E9PKI6_HUMAN,tr|A0A1W2PQ43|A0A1W2PQ43_HUMAN,tr|E9PK91|E9PK91_HUMAN,tr|E9PK09|E9PK09_HUMAN,tr|E9PQN2|E9PQN2_HUMAN" 6 1571.8348 2.73 104625 18517 3 1571.840938 524.9522 Bcl-2-associated transcription factor 1 OS=Homo sapiens OX=9606 GN=BCLAF1 PE=1 SV=2 6.75 3047.4 - 570213 - - - 3.9177 - 2.558 0.542 - 134.4 1 2 1 0.0062 13 0 0 0 3.54E+07 1.30E+07 - - - 7.1276 1 221125_WJC_METTL3_EV_vs_WT_F07.18519.18519.4 3.62E-08 17/138 R.VPLEDLSEDPVVGHLGTSTEEGKK.V "sp|Q9UBP6|TRMB_HUMAN,tr|H0YIH0|H0YIH0_HUMAN" 2 2535.2704 0.8 104627 18519 4 2535.274745 634.8249 tRNA (guanine-N(7)-)-methyltransferase OS=Homo sapiens OX=9606 GN=METTL1 PE=1 SV=1 4.35 3047.7 - 296920 - - - 1.7028 - 3.4 0.554 - 226.8 1 2 0 0.0043 24 0 0 0 6.97E+06 8.76E+06 - - - 4.4396 0.9957 221125_WJC_METTL3_EV_vs_WT_F07.18521.18521.3 1.95E-07 14/76 K.EAVQKEEPIPQEPQWSLPSK.E "sp|Q3KQU3|MA7D1_HUMAN,tr|D3DPS3|D3DPS3_HUMAN" 2 2319.1747 0.86 104629 18521 3 2319.190174 774.0655 MAP7 domain-containing protein 1 OS=Homo sapiens OX=9606 GN=MAP7D1 PE=1 SV=1 4.49 3047.9 - 258153 - - - 6.6821 - 2.729 0.551 - 164.6 1 2 1 0.0155 20 0 0 0 2.69E+06 3.12E+06 - - - 7.1144 0.9998 221125_WJC_METTL3_EV_vs_WT_F07.18525.18525.3 2.61E-07 Dec-88 K.FDDGEDPLDAESQQGGGGNPFHR.S "sp|Q13217|DNJC3_HUMAN,tr|X6R9L0|X6R9L0_HUMAN" 2 2444.0265 3 104633 18525 3 2444.038029 815.6828 DnaJ homolog subfamily C member 3 OS=Homo sapiens OX=9606 GN=DNAJC3 PE=1 SV=1 3.96 3048.5 - 173679 - - - 4.7135 - 2.661 0.614 - 138.7 1 2 0 0.0115 23 0 0 0 4.89E+06 1.63E+06 - - - 7.6783 0.9995 221125_WJC_METTL3_EV_vs_WT_F07.18527.18527.4 8.74E-08 24/114 K.ARPFPDGLAEDIDKGEVSAR.Q sp|P13639|EF2_HUMAN 1 2142.0705 0.53 104634 18527 4 2142.079733 536.5249 Elongation factor 2 OS=Homo sapiens OX=9606 GN=EEF2 PE=1 SV=4 4.44 3048.7 - 2.57E+06 - - - 4.2888 - 4.396 0.581 - 465.4 1 2 1 0.0092 20 0 0 0 1.14E+08 2.13E+08 - - - 4.7755 0.9999 221125_WJC_METTL3_EV_vs_WT_F07.18529.18529.4 1.69E-09 27/150 R.TLVNKEEPPKELPAAEPVLSPLEGTK.M "sp|Q9BY77|PDIP3_HUMAN,tr|F6VRR5|F6VRR5_HUMAN" 2 2785.5113 1.75 104635 18529 4 2785.519041 697.3851 Polymerase delta-interacting protein 3 OS=Homo sapiens OX=9606 GN=POLDIP3 PE=1 SV=2 4.65 3048.9 - 3.85E+06 - - - 2.7693 - 4.308 0.608 - 470.3 1 2 2 0.0077 26 0 0 0 1.15E+09 6.58E+08 - - - 4.9766 0.9999 221125_WJC_METTL3_EV_vs_WT_F07.18532.18532.4 6.54E-10 21/138 R.VPLEDLSEDPVVGHLGTSTEEGK[136.11]K[136.11].V "sp|Q9UBP6|TRMB_HUMAN,tr|H0YIH0|H0YIH0_HUMAN" 2 2551.2988 0.78 104638 18532 4 2551.308552 638.832 tRNA (guanine-N(7)-)-methyltransferase OS=Homo sapiens OX=9606 GN=METTL1 PE=1 SV=1 4.35 3049.3 - 535583 - - - 3.8114 - 3.98 0.582 - 352.6 1 2 0 0.0097 24 0 0 0 6.90E+06 8.90E+06 - - - 4.7324 0.999 221125_WJC_METTL3_EV_vs_WT_F07.18533.18533.4 4.20E-05 19/132 R.KELPDPSQRPLGEPSAGLGEYLK.G "sp|Q9HC52|CBX8_HUMAN,tr|C9J6K3|C9J6K3_HUMAN" 2 2480.2911 2.14 104639 18533 4 2480.30054 621.0801 Chromobox protein homolog 8 OS=Homo sapiens OX=9606 GN=CBX8 PE=1 SV=3 4.87 3049.4 - 521005 - - - 3.8044 - 2.519 0.383 - 180.5 1 2 0 0.0094 23 0 0 0 5.64E+07 2.64E+07 - - - 2.8563 0.9998 221125_WJC_METTL3_EV_vs_WT_F07.18534.18534.4 0.0005 17/228 R.IFPPETSASVAATPPPSTASAPAAVNSSASADKPLSNMK.L "sp|P09874|PARP1_HUMAN,tr|A0A7I2V3E1|A0A7I2V3E1_HUMAN" 2 3766.8724 1.67 104640 18534 4 3766.879612 942.7254 Poly [ADP-ribose] polymerase 1 OS=Homo sapiens OX=9606 GN=PARP1 PE=1 SV=4 6.07 3049.6 - 332085 - - - 1.9223 - 3.357 0.39 - 90 1 2 0 0.0072 39 0 0 0 7.71E+06 4.61E+06 - - - 2.9699 0.9993 221125_WJC_METTL3_EV_vs_WT_F07.18535.18535.4 8.78E-05 11/108 R.VNDQEGR[166.11]EEFYVHYVGFNR[166.11].R sp|Q9H7Z6|KAT8_HUMAN 1 2377.099 2.03 104641 18535 4 2377.105519 595.282 Histone acetyltransferase KAT8 OS=Homo sapiens OX=9606 GN=KAT8 PE=1 SV=2 4.83 3049.7 - 308030 - - - 2.7222 - 2.186 0.456 - 88.6 1 2 1 0.0065 19 0 0 0 4.32E+06 2.13E+06 - - - 3.4578 0.892 221125_WJC_METTL3_EV_vs_WT_F07.18539.18539.4 0.000378 Dec-84 N.GDK[136.11]EIGNIISDAMK[136.11]K[136.11].V "sp|P10809|CH60_HUMAN,tr|A0A7I2V599|A0A7I2V599_HUMAN,tr|E7EXB4|E7EXB4_HUMAN,tr|A0A7I2YQ71|A0A7I2YQ71_HUMAN,tr|E7ESH4|E7ESH4_HUMAN,tr|A0A7I2V5M1|A0A7I2V5M1_HUMAN,tr|A0A7I2V5K3|A0A7I2V5K3_HUMAN,tr|A0A7I2V369|A0A7I2V369_HUMAN" 8 1641.8822 1.39 104645 18539 4 1641.884565 411.4778 "60 kDa heat shock protein, mitochondrial OS=Homo sapiens OX=9606 GN=HSPD1 PE=1 SV=2" 6.12 3050.2 - 153122 - - - 1.4362 - 1.988 0.376 - 101.5 1 1 1 0.0024 15 0 0 0 7.82E+06 5.64E+06 - - - 2.7439 1 221125_WJC_METTL3_EV_vs_WT_F07.18542.18542.4 4.81E-10 35/168 R.EPPPPYVTPATFETPEVHAGTGVVGNKPR.P "sp|Q96DF8|ESS2_HUMAN,tr|F8WEF8|F8WEF8_HUMAN" 2 3043.5403 1.16 104646 18542 4 3043.549027 761.8924 Splicing factor ESS-2 homolog OS=Homo sapiens OX=9606 GN=ESS2 PE=1 SV=1 5.5 3050.6 - 1.77E+06 - - - 2.8556 - 5.789 0.654 - 890.3 1 1 0 0.0087 29 0 0 0 8.07E+07 6.95E+07 - - - 5.4572 0.9994 221125_WJC_METTL3_EV_vs_WT_F07.18543.18543.4 0.00036 Dec-72 K.LKDLFDYSPPLHK.N "sp|Q9NYF8|BCLF1_HUMAN,tr|E9PKI6|E9PKI6_HUMAN,tr|A0A1W2PQ43|A0A1W2PQ43_HUMAN,tr|E9PK91|E9PK91_HUMAN,tr|E9PK09|E9PK09_HUMAN,tr|E9PQN2|E9PQN2_HUMAN" 6 1571.8348 2.48 104647 18543 4 1571.837671 393.966 Bcl-2-associated transcription factor 1 OS=Homo sapiens OX=9606 GN=BCLAF1 PE=1 SV=2 6.75 3050.7 - 1.82E+06 - - - 1.8393 - 1.775 0.424 - 53 1 2 1 0.0029 13 0 0 0 6.73E+07 2.72E+07 - - - 3.1284 1 221125_WJC_METTL3_EV_vs_WT_F07.18544.18544.3 4.54E-09 26/100 R.TLVNKEEPPKELPAAEPVLSPLEGTK.M "sp|Q9BY77|PDIP3_HUMAN,tr|F6VRR5|F6VRR5_HUMAN" 2 2785.5113 1.84 104648 18544 3 2785.515529 929.5111 Polymerase delta-interacting protein 3 OS=Homo sapiens OX=9606 GN=POLDIP3 PE=1 SV=2 4.65 3050.8 - 870611 - - - 1.5085 - 4.66 0.693 - 544.7 1 2 2 0.0042 26 0 0 0 1.51E+08 8.19E+07 - - - 9.8058 1 221125_WJC_METTL3_EV_vs_WT_F07.18546.18546.3 7.36E-16 27/100 R.TLVNK[136.11]EEPPK[136.11]ELPAAEPVLSPLEGTK[136.11].M "sp|Q9BY77|PDIP3_HUMAN,tr|F6VRR5|F6VRR5_HUMAN" 2 2809.5539 1.84 104650 18546 3 2809.560299 937.5253 Polymerase delta-interacting protein 3 OS=Homo sapiens OX=9606 GN=POLDIP3 PE=1 SV=2 4.65 3051.1 - 521756 - - - 2.268 - 4.839 0.701 - 597.3 1 2 2 0.0064 26 0 0 0 1.51E+08 8.19E+07 - - - 9.9811 0.9996 221125_WJC_METTL3_EV_vs_WT_F07.18548.18548.4 1.37E-06 19/132 R.K[136.11]ELPDPSQR[166.11]PLGEPSAGLGEYLK[136.11].G "sp|Q9HC52|CBX8_HUMAN,tr|C9J6K3|C9J6K3_HUMAN" 2 2506.3278 2.13 104652 18548 4 2506.338635 627.5892 Chromobox protein homolog 8 OS=Homo sapiens OX=9606 GN=CBX8 PE=1 SV=3 4.87 3051.4 - 444932 - - - 4.3334 - 2.96 0.465 - 115.5 1 2 0 0.0109 23 0 0 0 5.65E+07 2.65E+07 - - - 3.6219 0.9992 221125_WJC_METTL3_EV_vs_WT_F07.18549.18549.4 4.00E-06 14/96 R.EKDRDPEAQFEMPYVVR.L "sp|O14744|ANM5_HUMAN,tr|H0YJD3|H0YJD3_HUMAN,tr|H7BZ44|H7BZ44_HUMAN" 3 2107.9997 2.65 104653 18549 4 2108.008706 528.0072 Protein arginine N-methyltransferase 5 OS=Homo sapiens OX=9606 GN=PRMT5 PE=1 SV=4 4.51 3051.5 - 417217 - - - 4.277 - 2.946 0.529 - 136.4 1 2 2 0.009 17 0 0 0 9.16E+08 3.46E+08 - - - 4.203 0.9994 221125_WJC_METTL3_EV_vs_WT_F07.18550.18550.3 0.000309 Oct-48 K.LK[136.11]DLFDYSPPLHK[136.11].N "sp|Q9NYF8|BCLF1_HUMAN,tr|E9PKI6|E9PKI6_HUMAN,tr|A0A1W2PQ43|A0A1W2PQ43_HUMAN,tr|E9PK91|E9PK91_HUMAN,tr|E9PK09|E9PK09_HUMAN,tr|E9PQN2|E9PQN2_HUMAN" 6 1587.8632 2.77 104654 18550 3 1587.865637 530.295 Bcl-2-associated transcription factor 1 OS=Homo sapiens OX=9606 GN=BCLAF1 PE=1 SV=2 6.75 3051.6 - 380862 - - - 1.5474 - 2.007 0.432 - 101.6 1 2 1 0.0025 13 0 0 0 3.54E+07 1.28E+07 - - - 5.2445 0.9863 221125_WJC_METTL3_EV_vs_WT_F07.18551.18551.4 3.77E-07 14/84 N.GDKEIGNIISDAMKK.V "sp|P10809|CH60_HUMAN,tr|A0A7I2V599|A0A7I2V599_HUMAN,tr|E7EXB4|E7EXB4_HUMAN,tr|A0A7I2YQ71|A0A7I2YQ71_HUMAN,tr|E7ESH4|E7ESH4_HUMAN,tr|A0A7I2V5M1|A0A7I2V5M1_HUMAN,tr|A0A7I2V5K3|A0A7I2V5K3_HUMAN,tr|A0A7I2V369|A0A7I2V369_HUMAN" 8 1617.8396 1.37 104655 18551 4 1617.842483 405.4672 "60 kDa heat shock protein, mitochondrial OS=Homo sapiens OX=9606 GN=HSPD1 PE=1 SV=2" 6.12 3051.8 - 346493 - - - 1.7777 - 2.56 0.552 - 181.5 1 1 1 0.0029 15 0 0 0 7.82E+06 5.71E+06 - - - 4.3662 0.9999 221125_WJC_METTL3_EV_vs_WT_F07.18563.18563.4 9.17E-09 20/156 K.EAENPEGEEKEAATLEVERPLPMEVEK.N sp|P51858|HDGF_HUMAN 1 3052.4547 0.55 104664 18563 4 3052.45595 764.1209 Hepatoma-derived growth factor OS=Homo sapiens OX=9606 GN=HDGF PE=1 SV=1 4.12 3053.3 - 1.09E+06 - - - 0.417 - 3.177 0.56 - 113.8 1 2 1 0.0013 27 0 0 0 7.25E+06 1.32E+07 - - - 4.4616 0.9996 221125_WJC_METTL3_EV_vs_WT_F07.18564.18564.4 6.86E-05 14/108 K.K[136.11]R[166.11]VEDAYILTC[160.03]NVSLEYEK[136.11].T sp|P40227|TCPZ_HUMAN 1 2355.1991 0.31 104665 18564 4 2355.203119 589.807 T-complex protein 1 subunit zeta OS=Homo sapiens OX=9606 GN=CCT6A PE=1 SV=3 4.87 3053.4 - 646724 - - - 1.72 - 3.068 0.433 - 138.5 1 2 1 0.0041 19 0 0 0 7.22E+06 2.34E+07 - - - 3.3729 0.9999 221125_WJC_METTL3_EV_vs_WT_F07.18565.18565.3 4.74E-06 16/88 R.KELPDPSQRPLGEPSAGLGEYLK.G "sp|Q9HC52|CBX8_HUMAN,tr|C9J6K3|C9J6K3_HUMAN" 2 2480.2911 3.53 104666 18565 3 2480.293551 827.771 Chromobox protein homolog 8 OS=Homo sapiens OX=9606 GN=CBX8 PE=1 SV=3 4.87 3053.6 - 562495 - - - 0.9866 - 2.634 0.454 - 143.3 1 2 0 0.0024 23 0 0 0 1.42E+07 4.02E+06 - - - 5.873 0.9999 221125_WJC_METTL3_EV_vs_WT_F07.18568.18568.4 2.55E-09 15/84 R.HNEFNPQHSLLVQFR.N sp|Q99717|SMAD5_HUMAN 1 1864.9333 1.52 104669 18568 4 1864.936332 467.2406 Mothers against decapentaplegic homolog 5 OS=Homo sapiens OX=9606 GN=SMAD5 PE=1 SV=1 6.92 3053.9 - 255959 - - - 1.6446 - 3.134 0.462 - 269.7 1 2 0 0.0031 15 0 0 0 3.62E+07 2.38E+07 - - - 3.6551 0.9898 221125_WJC_METTL3_EV_vs_WT_F07.18569.18569.3 0.00602 Aug-60 K.YFLHDDRDDGVDYWAK.R "sp|Q9NYF8|BCLF1_HUMAN,tr|H0YF14|H0YF14_HUMAN" 2 2013.8857 2.92 104670 18569 3 2013.890018 672.3025 Bcl-2-associated transcription factor 1 OS=Homo sapiens OX=9606 GN=BCLAF1 PE=1 SV=2 4.28 3054.1 - 162621 - - - 2.1411 - 1.602 0.316 - 72.2 1 2 1 0.0043 16 0 0 0 9.75E+07 3.34E+07 - - - 3.2711 1 221125_WJC_METTL3_EV_vs_WT_F07.18571.18571.3 1.07E-09 14/124 R.LQAALDDEEAGGRPAMEPGNGSLDLGGDSAGR.S "sp|Q00839|HNRPU_HUMAN,tr|A0A1W2PPS1|A0A1W2PPS1_HUMAN,tr|A0A1X7SBS1|A0A1X7SBS1_HUMAN" 3 3125.432 1.35 104671 18571 3 3125.430032 1042.8179 Heterogeneous nuclear ribonucleoprotein U OS=Homo sapiens OX=9606 GN=HNRNPU PE=1 SV=6 3.9 3054.3 - 279115 - - - -0.6246 - 3.4 0.664 - 131.3 1 2 0 -0.002 32 0 0 0 4.17E+06 3.09E+06 - - - 8.7579 1 221125_WJC_METTL3_EV_vs_WT_F07.18573.18573.3 1.73E-10 31/76 K.AR[166.11]PFPDGLAEDIDK[136.11]GEVSAR[166.11].Q sp|P13639|EF2_HUMAN 1 2170.1013 0.63 104672 18573 3 2170.100119 724.3744 Elongation factor 2 OS=Homo sapiens OX=9606 GN=EEF2 PE=1 SV=4 4.44 3054.5 - 2.29E+06 - - - -0.5378 - 5.737 0.673 - 1257.6 1 2 1 -0.0012 20 0 0 0 4.33E+07 6.87E+07 - - - 10.2811 0.9998 221125_WJC_METTL3_EV_vs_WT_F07.18574.18574.3 0.000374 14/48 R.GYFEYIEENKYSR.A "sp|Q00839|HNRPU_HUMAN,tr|Q5RI18|Q5RI18_HUMAN,tr|A0A1W2PP35|A0A1W2PP35_HUMAN,tr|A0A1W2PPS1|A0A1W2PPS1_HUMAN,tr|A0A1W2PRI6|A0A1W2PRI6_HUMAN" 5 1696.7733 2.24 104673 18574 3 1696.775193 566.5984 Heterogeneous nuclear ribonucleoprotein U OS=Homo sapiens OX=9606 GN=HNRNPU PE=1 SV=6 4.79 3054.6 - 1.12E+06 - - - 1.1145 - 2.721 0.44 - 210.4 1 2 1 0.0019 13 0 0 0 3.99E+07 1.78E+07 - - - 6.159 0.9999 221125_WJC_METTL3_EV_vs_WT_F07.18576.18576.4 1.91E-11 25/156 K.EAENPEGEEK[136.11]EAATLEVER[166.11]PLPMEVEK[136.11].N sp|P51858|HDGF_HUMAN 1 3078.4913 0.56 104675 18576 4 3078.490589 770.6301 Hepatoma-derived growth factor OS=Homo sapiens OX=9606 GN=HDGF PE=1 SV=1 4.12 3054.8 - 1.29E+06 - - - -0.2462 - 3.979 0.528 - 304.2 1 2 1 -0.0008 27 0 0 0 7.25E+06 1.29E+07 - - - 4.2536 0.9999 221125_WJC_METTL3_EV_vs_WT_F07.18582.18582.4 8.76E-08 25/150 R.TLVNK[136.11]EEPPK[136.11]ELPAAEPVLSPLEGTK[136.11].M "sp|Q9BY77|PDIP3_HUMAN,tr|F6VRR5|F6VRR5_HUMAN" 2 2809.5539 1.75 104679 18582 4 2809.55236 703.3958 Polymerase delta-interacting protein 3 OS=Homo sapiens OX=9606 GN=POLDIP3 PE=1 SV=2 4.65 3055.7 - 1.53E+07 - - - -0.5577 - 4.182 0.602 - 357.7 1 2 2 -0.0016 26 0 0 0 1.15E+09 6.58E+08 - - - 4.9167 0.9995 221125_WJC_METTL3_EV_vs_WT_F07.18585.18585.4 6.46E-06 Dec-90 K.YFLHDDR[166.11]DDGVDYWAK[136.11].R "sp|Q9NYF8|BCLF1_HUMAN,tr|H0YF14|H0YF14_HUMAN" 2 2031.9082 2.5 104682 18585 4 2031.903383 508.9843 Bcl-2-associated transcription factor 1 OS=Homo sapiens OX=9606 GN=BCLAF1 PE=1 SV=2 4.28 3056 - 315701 - - - -2.3589 - 2.225 0.459 - 91 1 2 1 -0.0048 16 0 0 0 1.23E+08 4.93E+07 - - - 3.5015 1 221125_WJC_METTL3_EV_vs_WT_F07.18589.18589.3 3.11E-09 24/64 R.EK[136.11]DR[166.11]DPEAQFEMPYVVR[166.11].L "sp|O14744|ANM5_HUMAN,tr|H0YJD3|H0YJD3_HUMAN,tr|H7BZ44|H7BZ44_HUMAN" 3 2136.0304 2.36 104684 18589 3 2136.030274 713.0174 Protein arginine N-methyltransferase 5 OS=Homo sapiens OX=9606 GN=PRMT5 PE=1 SV=4 4.51 3056.5 - 1.75E+06 - - - -0.073 - 3.971 0.6 - 703.9 1 2 2 -0.0002 17 0 0 0 4.52E+08 1.92E+08 - - - 8.7132 1 221125_WJC_METTL3_EV_vs_WT_F07.18590.18590.3 3.55E-06 17/52 K.HGYIGEFEIIDDHR[166.11].A "sp|P62244|RS15A_HUMAN,tr|I3L246|I3L246_HUMAN,tr|I3L3P7|I3L3P7_HUMAN,tr|H3BN98|H3BN98_HUMAN" 4 1709.8037 1.28 104685 18590 3 1709.802835 570.9418 40S ribosomal protein S15a OS=Homo sapiens OX=9606 GN=RPS15A PE=1 SV=2 4.72 3056.6 - 1.09E+06 - - - -0.5082 - 3.167 0.606 - 413.7 1 2 0 -0.0009 14 0 0 0 2.70E+07 2.11E+07 - - - 8.3596 0.9998 221125_WJC_METTL3_EV_vs_WT_F07.18591.18591.4 3.32E-05 Dec-96 R.EK[136.11]DR[166.11]DPEAQFEMPYVVR[166.11].L "sp|O14744|ANM5_HUMAN,tr|H0YJD3|H0YJD3_HUMAN,tr|H7BZ44|H7BZ44_HUMAN" 3 2136.0304 2.65 104686 18591 4 2136.031821 535.0149 Protein arginine N-methyltransferase 5 OS=Homo sapiens OX=9606 GN=PRMT5 PE=1 SV=4 4.51 3056.6 - 3.53E+06 - - - 0.6512 - 2.4 0.463 - 68.6 1 2 2 0.0014 17 0 0 0 9.16E+08 3.46E+08 - - - 3.5595 0.9999 221125_WJC_METTL3_EV_vs_WT_F07.18594.18594.3 2.44E-05 13/72 R.HPHDIIDDINSGAVEC[160.03]PAS.- sp|P30050|RL12_HUMAN 1 2045.9113 - 104689 18594 3 2045.914426 682.9777 60S ribosomal protein L12 OS=Homo sapiens OX=9606 GN=RPL12 PE=1 SV=1 4.21 3057 - 476801 - - - 1.5431 - 2.776 0.449 - 203.4 1 2 0 0.0032 19 0 0 0 - - - - - 6.0535 0.9999 221125_WJC_METTL3_EV_vs_WT_F07.18600.18600.3 7.97E-11 17/72 K.K[136.11]R[166.11]VEDAYILTC[160.03]NVSLEYEK[136.11].T sp|P40227|TCPZ_HUMAN 1 2355.1991 0.86 104693 18600 3 2355.197567 786.0736 T-complex protein 1 subunit zeta OS=Homo sapiens OX=9606 GN=CCT6A PE=1 SV=3 4.87 3057.8 - 772970 - - - -0.6373 - 3.715 0.534 - 427 1 2 1 -0.0015 19 0 0 0 1.82E+07 2.11E+07 - - - 7.7174 1 221125_WJC_METTL3_EV_vs_WT_F07.18602.18602.4 6.30E-10 18/84 R.HNEFNPQHSLLVQFR[166.11].N sp|Q99717|SMAD5_HUMAN 1 1874.9415 1.5 104695 18602 4 1874.940634 469.7427 Mothers against decapentaplegic homolog 5 OS=Homo sapiens OX=9606 GN=SMAD5 PE=1 SV=1 6.92 3058.1 - 568865 - - - -0.4805 - 3.15 0.594 - 328.1 1 2 0 -0.0009 15 0 0 0 3.55E+07 2.37E+07 - - - 4.8065 0.9999 221125_WJC_METTL3_EV_vs_WT_F07.18603.18603.3 5.07E-09 13/92 K.FNIDGNNERPSPPPNVDYPLDGEK.L "sp|Q9NZ32|ARP10_HUMAN,tr|V9GYX7|V9GYX7_HUMAN" 2 2683.2514 3.83 104696 18603 3 2683.256476 895.4244 Actin-related protein 10 OS=Homo sapiens OX=9606 GN=ACTR10 PE=1 SV=1 4.11 3058.2 - 235714 - - - 1.8828 - 2.74 0.486 - 131.7 1 2 0 0.0051 24 0 0 0 5.30E+06 1.38E+06 - - - 6.2981 1 221125_WJC_METTL3_EV_vs_WT_F07.18608.18608.3 2.80E-08 21/56 R.HNEFNPQHSLLVQFR.N sp|Q99717|SMAD5_HUMAN 1 1864.9333 1.43 104699 18608 3 1864.93256 622.6517 Mothers against decapentaplegic homolog 5 OS=Homo sapiens OX=9606 GN=SMAD5 PE=1 SV=1 6.92 3058.8 - 1.07E+06 - - - -0.378 - 4.222 0.595 - 700.6 1 2 0 -0.0007 15 0 0 0 5.54E+07 3.87E+07 - - - 8.9318 0.9998 221125_WJC_METTL3_EV_vs_WT_F07.18612.18612.4 0.00095 9/138 R.EPNAEVPRPIPHIGPDYIPTEEER.R "sp|Q9NX40|OCAD1_HUMAN,tr|D6RA54|D6RA54_HUMAN,tr|D6RBC5|D6RBC5_HUMAN,tr|D6R918|D6R918_HUMAN,tr|D6RF07|D6RF07_HUMAN,tr|D6RG39|D6RG39_HUMAN,tr|D6RDI5|D6RDI5_HUMAN,tr|D6RIT9|D6RIT9_HUMAN,tr|D6RC55|D6RC55_HUMAN" 9 2754.3613 3.84 104701 18612 4 2754.357843 689.5976 OCIA domain-containing protein 1 OS=Homo sapiens OX=9606 GN=OCIAD1 PE=1 SV=1 4.41 3059.3 - 241940 - - - -1.2584 - 1.773 0.38 - 30.7 1 2 0 -0.0035 24 0 0 0 4.29E+06 1.12E+06 - - - 2.7164 1 221125_WJC_METTL3_EV_vs_WT_F07.18615.18615.4 2.68E-09 25/156 K.ELESARPQLLAPETALRPNDGAEELQR.R "sp|Q96NU1|SAM11_HUMAN,tr|A0A087WYW1|A0A087WYW1_HUMAN,tr|A0A087WX24|A0A087WX24_HUMAN,tr|A0A087X1J5|A0A087X1J5_HUMAN,tr|A0A087X223|A0A087X223_HUMAN,tr|H7BY14|H7BY14_HUMAN,tr|A0A087WXB3|A0A087WXB3_HUMAN,tr|H7C3J6|H7C3J6_HUMAN,tr|A0A087WYU3|A0A087WYU3_HUMAN,tr|A0A087WU74|A0A087WU74_HUMAN" 10 3002.5421 2.44 104703 18615 4 3002.543495 751.6428 Sterile alpha motif domain-containing protein 11 OS=Homo sapiens OX=9606 GN=SAMD11 PE=1 SV=3 4.42 3059.7 - 595755 - - - 0.4556 - 4.16 0.588 - 261.5 1 2 0 0.0014 27 0 0 0 1.46E+07 5.98E+06 - - - 4.7896 1 221125_WJC_METTL3_EV_vs_WT_F07.18617.18617.3 4.18E-09 19/60 K.YFLHDDR[166.11]DDGVDYWAK[136.11].R "sp|Q9NYF8|BCLF1_HUMAN,tr|H0YF14|H0YF14_HUMAN" 2 2031.9082 2.98 104705 18617 3 2031.907205 678.31 Bcl-2-associated transcription factor 1 OS=Homo sapiens OX=9606 GN=BCLAF1 PE=1 SV=2 4.28 3059.9 - 987704 - - - -0.4779 - 3.189 0.631 - 413.5 1 2 1 -0.001 16 0 0 0 1.05E+08 3.51E+07 - - - 8.5504 1 221125_WJC_METTL3_EV_vs_WT_F07.18618.18618.4 1.45E-13 20/162 K.LGDLKEEGDVMDKTNGLPVQNGIDADVK.D "sp|Q14671|PUM1_HUMAN,tr|Q5T1Z8|Q5T1Z8_HUMAN,tr|H0YEH2|H0YEH2_HUMAN,tr|Q5T1Z4|Q5T1Z4_HUMAN" 4 2969.4652 14.24 104706 18618 4 2969.462215 743.3736 Pumilio homolog 1 OS=Homo sapiens OX=9606 GN=PUM1 PE=1 SV=3 4.09 3060.1 - 745149 - - - -0.9992 - 4.22 0.619 - 226.6 1 2 2 -0.003 28 0 0 0 4.83E+07 3.39E+06 - - - 5.06 1 221125_WJC_METTL3_EV_vs_WT_F07.18623.18623.3 8.85E-10 20/56 R.HNEFNPQHSLLVQFR[166.11].N sp|Q99717|SMAD5_HUMAN 1 1874.9415 1.44 104709 18623 3 1874.940604 625.9878 Mothers against decapentaplegic homolog 5 OS=Homo sapiens OX=9606 GN=SMAD5 PE=1 SV=1 6.92 3060.7 - 1.43E+06 - - - -0.4965 - 3.957 0.651 - 634.5 1 2 0 -0.0009 15 0 0 0 5.54E+07 3.85E+07 - - - 9.3869 1 221125_WJC_METTL3_EV_vs_WT_F07.18626.18626.3 2.07E-10 14/116 K.EDSGMIPLAGTAPGAEGPAPGDSQAVRPYK.Q sp|Q8N0Y2|ZN444_HUMAN 1 2938.4131 3.8 104712 18626 3 2938.412675 980.4783 Zinc finger protein 444 OS=Homo sapiens OX=9606 GN=ZNF444 PE=1 SV=1 4.32 3061.1 - 364945 - - - -0.1399 - 3.066 0.647 - 114.6 1 2 0 -0.0004 30 0 0 0 3.59E+06 9.44E+05 - - - 8.3309 0.9999 221125_WJC_METTL3_EV_vs_WT_F07.18627.18627.3 2.37E-08 Oct-64 K.TQLIAHDKEVYDIAFSR.A "sp|P61962|DCAF7_HUMAN,tr|A0A087WWI6|A0A087WWI6_HUMAN" 2 2005.0269 10.08 104713 18627 3 2005.025416 669.3496 DDB1- and CUL4-associated factor 7 OS=Homo sapiens OX=9606 GN=DCAF7 PE=1 SV=1 5.35 3061.2 - 325534 - - - -0.7357 - 2.624 0.56 - 119.1 1 2 1 -0.0015 17 0 0 0 9.58E+06 9.50E+05 - - - 7.2202 1 221125_WJC_METTL3_EV_vs_WT_F07.18633.18633.4 5.49E-07 14/108 R.GLLQDDAHPTLVTYADHSK[136.11].L "sp|Q86U44|MTA70_HUMAN,tr|F5H6D8|F5H6D8_HUMAN,tr|H0YFV6|H0YFV6_HUMAN,tr|B4DTN4|B4DTN4_HUMAN" 4 2088.0367 0.001 104717 18633 4 2088.038917 523.0165 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 5.13 3062 - 705872 - - - 1.046 - 3.027 0.52 - 204.4 1 2 0 0.0022 19 0 0 0 0.00E+00 1.26E+07 - - - 4.1261 1 221125_WJC_METTL3_EV_vs_WT_F07.18640.18640.2 4.69E-08 14/36 R.HPHDIIDDINSGAVEC[160.03]PAS.- sp|P30050|RL12_HUMAN 1 2045.9113 - 104721 18640 2 2045.909397 1023.9629 60S ribosomal protein L12 OS=Homo sapiens OX=9606 GN=RPL12 PE=1 SV=1 4.21 3062.9 - 1.17E+06 - - - -0.915 - 2.765 0.663 - 273.2 1 2 0 -0.0019 19 0 0 0 - - - - - 6.4378 0.9976 221125_WJC_METTL3_EV_vs_WT_F07.18643.18643.4 0.00121 11/102 K.GETK[136.11]SFYPEEVSSMVLTK[136.11].M "sp|P11142|HSP7C_HUMAN,tr|E9PQQ4|E9PQQ4_HUMAN,tr|E9PKE3|E9PKE3_HUMAN,tr|E9PN89|E9PN89_HUMAN,tr|E9PLF4|E9PLF4_HUMAN,tr|E9PK54|E9PK54_HUMAN,tr|E9PN25|E9PN25_HUMAN,tr|E9PPY6|E9PPY6_HUMAN,tr|E9PQK7|E9PQK7_HUMAN" 9 2047.0155 0.17 104724 18643 4 2047.011251 512.7611 Heat shock cognate 71 kDa protein OS=Homo sapiens OX=9606 GN=HSPA8 PE=1 SV=1 4.79 3063.3 - 370715 - - - -2.0557 - 2.024 0.345 - 80.6 1 2 1 -0.0042 18 0 0 0 2.05E+06 1.18E+07 - - - 2.4692 0.9999 221125_WJC_METTL3_EV_vs_WT_F07.18647.18647.3 8.01E-05 Dec-64 K.K[136.11]IEVIK[136.11]PGDLGVDLTSK[136.11].L "sp|P38117|ETFB_HUMAN,tr|M0QY67|M0QY67_HUMAN" 2 1835.083 2.25 104726 18647 3 1835.080847 612.7016 Electron transfer flavoprotein subunit beta OS=Homo sapiens OX=9606 GN=ETFB PE=1 SV=3 6.12 3063.8 - 416455 - - - -1.1814 - 2.447 0.432 - 97.8 1 2 0 -0.0022 17 0 0 0 3.13E+07 1.39E+07 - - - 5.6165 1 221125_WJC_METTL3_EV_vs_WT_F07.18648.18648.3 7.58E-09 27/76 K.TTQFSC[160.03]TLGEKFEETTADGR.K "sp|Q01469|FABP5_HUMAN,tr|I6L8B7|I6L8B7_HUMAN" 2 2277.0219 1142.62 104727 18648 3 2277.020684 760.0146 Fatty acid-binding protein 5 OS=Homo sapiens OX=9606 GN=FABP5 PE=1 SV=3 4.41 3063.9 - 3.68E+06 - - - -0.552 - 4.89 0.675 - 981.2 1 2 1 -0.0013 20 0 0 0 1.19E+08 1.04E+05 - - - 9.9158 0.9996 221125_WJC_METTL3_EV_vs_WT_F07.18650.18650.2 0.00399 16-Aug R.VLDELTLAR.A "sp|Q04695|K1C17_HUMAN,sp|P02533|K1C14_HUMAN,sp|P08727|K1C19_HUMAN,sp|P08779|K1C16_HUMAN,sp|P19012|K1C15_HUMAN,tr|K7EPJ9|K7EPJ9_HUMAN,tr|C9JM50|C9JM50_HUMAN,tr|C9JTG5|C9JTG5_HUMAN,tr|F5GWP8|F5GWP8_HUMAN,tr|K7EMS3|K7EMS3_HUMAN,tr|A8MT21|A8MT21_HUMAN" 11 1028.5866 13.83 104729 18650 2 1028.585197 515.3006 "Keratin, type I cytoskeletal 17 OS=Homo sapiens OX=9606 GN=KRT17 PE=1 SV=2" 4.37 3064.1 - 398556 - - - -1.3737 - 1.869 0.383 - 169.6 1 2 0 -0.0014 9 0 0 0 1.34E+07 9.66E+05 - - - 3.6787 1 221125_WJC_METTL3_EV_vs_WT_F07.18653.18653.3 3.74E-12 23/76 K.AQQMHTGPVLDVC[160.03]WSDDGSK.V "sp|P78406|RAE1L_HUMAN,tr|B0QZ36|B0QZ36_HUMAN,tr|E9PQ57|E9PQ57_HUMAN,tr|E9PPG9|E9PPG9_HUMAN" 4 2229.9783 3.67 104730 18653 3 2229.975763 744.3334 mRNA export factor OS=Homo sapiens OX=9606 GN=RAE1 PE=1 SV=1 4.41 3064.5 - 3.85E+06 - - - -1.1386 - 4.002 0.665 - 734.4 1 2 0 -0.0025 20 0 0 0 1.41E+08 3.83E+07 - - - 9.3178 1 221125_WJC_METTL3_EV_vs_WT_F07.18654.18654.3 3.40E-11 23/80 K.DVEGSTSPQIGDK[136.11]VEFSISDK[136.11].Q "sp|O75534|CSDE1_HUMAN,tr|E9PLT0|E9PLT0_HUMAN" 2 2253.0983 0.46 104731 18654 3 2253.088253 752.0401 Cold shock domain-containing protein E1 OS=Homo sapiens OX=9606 GN=CSDE1 PE=1 SV=2 4.11 3064.6 - 2.24E+06 - - - -4.4756 - 3.769 0.621 - 316.1 1 2 1 -0.0101 21 0 0 0 4.28E+07 9.31E+07 - - - 8.6417 1 221125_WJC_METTL3_EV_vs_WT_F07.18656.18656.3 1.73E-09 19/64 K.KIEVIKPGDLGVDLTSK.L "sp|P38117|ETFB_HUMAN,tr|M0QY67|M0QY67_HUMAN" 2 1811.0404 2.24 104733 18656 3 1811.041436 604.6874 Electron transfer flavoprotein subunit beta OS=Homo sapiens OX=9606 GN=ETFB PE=1 SV=3 6.12 3064.9 - 646323 - - - 0.5638 - 3.732 0.526 - 294.2 1 2 0 0.001 17 0 0 0 3.12E+07 1.39E+07 - - - 7.7311 1 221125_WJC_METTL3_EV_vs_WT_F07.18661.18661.3 1.06E-09 20/100 K.NGFSSVQATQLQTTQSVEGATGSAVK.S "sp|Q14157|UBP2L_HUMAN,tr|F8W726|F8W726_HUMAN" 2 2595.2776 2.29 104736 18661 3 2595.279629 866.0998 Ubiquitin-associated protein 2-like OS=Homo sapiens OX=9606 GN=UBAP2L PE=1 SV=2 6 3065.6 - 1.97E+06 - - - 0.7668 - 3.644 0.582 - 351.1 1 2 0 0.002 26 0 0 0 3.37E+08 1.47E+08 - - - 8.0031 1 221125_WJC_METTL3_EV_vs_WT_F07.18662.18662.4 5.34E-08 14/96 K.KIEVIKPGDLGVDLTSK.L "sp|P38117|ETFB_HUMAN,tr|M0QY67|M0QY67_HUMAN" 2 1811.0404 2.11 104737 18662 4 1811.037093 453.7674 Electron transfer flavoprotein subunit beta OS=Homo sapiens OX=9606 GN=ETFB PE=1 SV=3 6.12 3065.7 - 791885 - - - -1.8343 - 2.716 0.528 - 164.2 1 2 0 -0.0033 17 0 0 0 2.22E+07 1.06E+07 - - - 4.1677 1 221125_WJC_METTL3_EV_vs_WT_F07.18663.18663.3 6.31E-10 21/100 K.NGFSSVQATQLQTTQSVEGATGSAVK[136.11].S "sp|Q14157|UBP2L_HUMAN,tr|F8W726|F8W726_HUMAN" 2 2603.2918 2.29 104738 18663 3 2603.289972 868.7712 Ubiquitin-associated protein 2-like OS=Homo sapiens OX=9606 GN=UBAP2L PE=1 SV=2 6 3065.8 - 827313 - - - -0.7172 - 3.614 0.651 - 447.2 1 2 0 -0.0019 26 0 0 0 3.37E+08 1.47E+08 - - - 8.7534 1 221125_WJC_METTL3_EV_vs_WT_F07.18665.18665.3 1.24E-14 19/108 R.GFGDGYNGYGGGPGGGNFGGSPGYGGGR.G "sp|P22626|ROA2_HUMAN,tr|A0A024RA28|A0A024RA28_HUMAN,tr|A0A7I2V323|A0A7I2V323_HUMAN,tr|A0A7I2V3P7|A0A7I2V3P7_HUMAN" 4 2494.0323 2.14 104740 18665 3 2494.033748 832.3514 Heterogeneous nuclear ribonucleoproteins A2\B1 OS=Homo sapiens OX=9606 GN=HNRNPA2B1 PE=1 SV=2 5.83 3066.1 - 554948 - - - 0.5954 - 3.633 0.711 - 263.2 1 2 0 0.0015 28 0 0 0 1.57E+07 7.34E+06 - - - 9.4345 0.9947 221125_WJC_METTL3_EV_vs_WT_F07.18670.18670.3 6.14E-08 20/92 V.AAFASSLVSGLNSSASEPAK[136.11]EPAK[136.11].K "sp|Q86U44|MTA70_HUMAN,tr|F5H6D8|F5H6D8_HUMAN,tr|H0YFV6|H0YFV6_HUMAN,tr|B4DTN4|B4DTN4_HUMAN" 4 2334.2038 0.05 104743 18670 3 2334.202776 779.0752 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 6.19 3066.7 - 786484 - - - -0.4408 - 3.767 0.578 - 409 1 1 1 -0.001 24 0 0 0 1.38E+06 2.75E+07 - - - 8.0643 0.9999 221125_WJC_METTL3_EV_vs_WT_F07.18676.18676.4 2.19E-05 19/108 R.SDKNNEFIVIHNGIITNYK.D "sp|Q06210|GFPT1_HUMAN,tr|A0A6I8PRN4|A0A6I8PRN4_HUMAN,tr|A0A6I8PTT9|A0A6I8PTT9_HUMAN" 3 2218.1382 1.19 104747 18676 4 2218.138141 555.5418 Glutamine--fructose-6-phosphate aminotransferase [isomerizing] 1 OS=Homo sapiens OX=9606 GN=GFPT1 PE=1 SV=3 6.47 3067.5 - 1.17E+06 - - - -0.041 - 3.938 0.496 - 316.4 1 2 1 -0.0001 19 0 0 0 8.49E+07 7.13E+07 - - - 4.0068 0.9999 221125_WJC_METTL3_EV_vs_WT_F07.18678.18678.4 1.54E-11 21/108 R.SDK[136.11]NNEFIVIHNGIITNYK[136.11].D "sp|Q06210|GFPT1_HUMAN,tr|A0A6I8PRN4|A0A6I8PRN4_HUMAN,tr|A0A6I8PTT9|A0A6I8PTT9_HUMAN" 3 2234.1666 1.19 104749 18678 4 2234.165798 559.5489 Glutamine--fructose-6-phosphate aminotransferase [isomerizing] 1 OS=Homo sapiens OX=9606 GN=GFPT1 PE=1 SV=3 6.47 3067.8 - 656202 - - - -0.3733 - 3.891 0.599 - 412 1 2 1 -0.0008 19 0 0 0 8.49E+07 7.13E+07 - - - 4.8991 1 221125_WJC_METTL3_EV_vs_WT_F07.18679.18679.3 3.84E-08 14/108 R.GFGDGYNGYGGGPGGGNFGGSPGYGGGR[166.11].G "sp|P22626|ROA2_HUMAN,tr|A0A024RA28|A0A024RA28_HUMAN,tr|A0A7I2V323|A0A7I2V323_HUMAN,tr|A0A7I2V3P7|A0A7I2V3P7_HUMAN" 4 2504.0405 2.14 104750 18679 3 2504.033898 835.6875 Heterogeneous nuclear ribonucleoproteins A2\B1 OS=Homo sapiens OX=9606 GN=HNRNPA2B1 PE=1 SV=2 5.83 3067.9 - 440773 - - - -2.6497 - 3.001 0.68 - 124.4 1 2 0 -0.0066 28 0 0 0 1.57E+07 7.34E+06 - - - 8.6478 0.8675 221125_WJC_METTL3_EV_vs_WT_F07.18685.18685.4 0.0387 13/138 Y.AVHGHFQPTQTGFLQPGGALSLQK.Q "sp|Q13227|GPS2_HUMAN,tr|I3L3Y9|I3L3Y9_HUMAN,tr|I3L1H4|I3L1H4_HUMAN,tr|I3L4X7|I3L4X7_HUMAN" 4 2518.3081 2.6 104753 18685 4 2518.308204 630.5843 G protein pathway suppressor 2 OS=Homo sapiens OX=9606 GN=GPS2 PE=1 SV=3 8.81 3068.6 - 481170 - - - 0.0449 - 2.455 0.28 - 70.1 1 1 0 0.0001 24 0 0 0 1.46E+07 5.62E+06 - - - 1.9514 1 221125_WJC_METTL3_EV_vs_WT_F07.18687.18687.3 1.29E-12 22/76 K.HNDDEQYAWESSAGGSFTVR[166.11].A "sp|P08238|HS90B_HUMAN,sp|P07900|HS90A_HUMAN,sp|Q14568|HS902_HUMAN" 3 2264.9598 0.72 104755 18687 3 2264.96484 755.9939 Heat shock protein HSP 90-beta OS=Homo sapiens OX=9606 GN=HSP90AB1 PE=1 SV=4 4.31 3068.9 - 589896 - - - 2.2151 - 4.37 0.759 - 625.3 1 2 0 0.005 20 0 0 0 1.72E+08 2.38E+08 - - - 10.5785 0.9196 221125_WJC_METTL3_EV_vs_WT_F07.18688.18688.4 0.0865 11/138 R.SAK[136.11]PVGPEDMGATAVYELDTEK[136.11]ER[166.11].D sp|O15541|R113A_HUMAN 1 2618.2744 0.54 104756 18688 4 2618.266292 655.5759 E3 ubiquitin-protein ligase RNF113A OS=Homo sapiens OX=9606 GN=RNF113A PE=1 SV=1 4.36 3069 - 501307 - - - -3.1036 - 2.205 0.211 - 52.3 1 2 1 -0.0081 24 0 0 0 2.40E+06 4.40E+06 - - - 1.3141 0.8796 221125_WJC_METTL3_EV_vs_WT_F07.18693.18693.4 1.20E-08 16/186 R.LQAALDDEEAGGRPAMEPGNGSLDLGGDSAGR.S "sp|Q00839|HNRPU_HUMAN,tr|A0A1W2PPS1|A0A1W2PPS1_HUMAN,tr|A0A1X7SBS1|A0A1X7SBS1_HUMAN" 3 3125.432 11.56 104759 18693 4 3126.406996 782.3653 Heterogeneous nuclear ribonucleoprotein U OS=Homo sapiens OX=9606 GN=HNRNPU PE=1 SV=6 3.9 3069.7 - 567370 - - - 311.9607 - 3.104 0.522 - 105.3 1 2 0 0.975 32 0 0 0 1.25E+08 1.08E+07 - - - 3.8414 0.9999 221125_WJC_METTL3_EV_vs_WT_F07.18696.18696.3 4.02E-08 22/72 R.SDKNNEFIVIHNGIITNYK.D "sp|Q06210|GFPT1_HUMAN,tr|A0A6I8PRN4|A0A6I8PRN4_HUMAN,tr|A0A6I8PTT9|A0A6I8PTT9_HUMAN" 3 2218.1382 1.15 104760 18696 3 2218.136853 740.3867 Glutamine--fructose-6-phosphate aminotransferase [isomerizing] 1 OS=Homo sapiens OX=9606 GN=GFPT1 PE=1 SV=3 6.47 3070.1 - 1.63E+06 - - - -0.6217 - 3.979 0.553 - 736.2 1 2 1 -0.0014 19 0 0 0 6.19E+07 5.39E+07 - - - 8.0979 0.9986 221125_WJC_METTL3_EV_vs_WT_F07.18698.18698.4 0.00309 13/192 R.SDSPVPTAPTSGGPK[136.11]PSTASAVPELATDPELEK[136.11].K "sp|Q86U44|MTA70_HUMAN,tr|B4E349|B4E349_HUMAN,tr|F5H6D8|F5H6D8_HUMAN,tr|B4DTN4|B4DTN4_HUMAN" 4 3248.6271 0.02 104761 18698 4 3248.62907 813.1641 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 4.18 3070.4 - 1.11E+06 - - - 0.607 - 2.249 0.28 - 62.9 1 2 0 0.002 33 0 0 0 1.48E+06 9.12E+07 - - - 1.9057 0.9268 221125_WJC_METTL3_EV_vs_WT_F07.18701.18701.4 2.12E-06 21/186 R.LQAALDDEEAGGR[166.11]PAMEPGNGSLDLGGDSAGR[166.11].S "sp|Q00839|HNRPU_HUMAN,tr|A0A1W2PPS1|A0A1W2PPS1_HUMAN,tr|A0A1X7SBS1|A0A1X7SBS1_HUMAN" 3 3145.4485 1.64 104763 18701 4 3146.424845 787.3694 Heterogeneous nuclear ribonucleoprotein U OS=Homo sapiens OX=9606 GN=HNRNPU PE=1 SV=6 3.9 3070.7 - 1.06E+06 - - - 310.3917 - 2.938 0.574 - 191.8 1 2 0 0.9763 32 0 0 0 1.32E+07 8.05E+06 - - - 4.2771 1 221125_WJC_METTL3_EV_vs_WT_F07.18702.18702.3 4.68E-14 31/76 K.ARPFPDGLAEDIDKGEVSAR.Q sp|P13639|EF2_HUMAN 1 2142.0705 0.59 104764 18702 3 2142.071581 715.0308 Elongation factor 2 OS=Homo sapiens OX=9606 GN=EEF2 PE=1 SV=4 4.44 3070.9 - 1.21E+06 - - - 0.4832 - 5.419 0.676 - 1156.9 1 2 1 0.001 20 0 0 0 6.48E+07 1.09E+08 - - - 10.1762 0.9998 221125_WJC_METTL3_EV_vs_WT_F07.18703.18703.4 3.03E-11 16/108 R.DVEHYVGSDK[136.11]EIDVIDVTR[166.11].Q "sp|Q9UPP1|PHF8_HUMAN,tr|H0Y3N9|H0Y3N9_HUMAN" 2 2206.0873 1.13 104765 18703 4 2206.079666 552.5291 Histone lysine demethylase PHF8 OS=Homo sapiens OX=9606 GN=PHF8 PE=1 SV=3 4.23 3071 - 544233 - - - -3.4432 - 3.391 0.606 - 169.1 1 2 1 -0.0076 19 0 0 0 8.90E+06 7.87E+06 - - - 4.9116 1 221125_WJC_METTL3_EV_vs_WT_F07.18707.18707.4 2.83E-11 18/144 R.SFDVNKPGC[160.03]EVDDLKGGVAGGSILK.G "sp|Q2VIR3|IF2GL_HUMAN,sp|P41091|IF2G_HUMAN" 2 2561.2796 0.98 104767 18707 4 2561.278092 641.3272 Eukaryotic translation initiation factor 2 subunit 3B OS=Homo sapiens OX=9606 GN=EIF2S3B PE=2 SV=2 4.68 3071.5 - 2.34E+06 - - - -0.5704 - 3.127 0.65 - 77.6 1 2 1 -0.0015 25 0 0 0 1.80E+08 1.85E+08 - - - 5.2459 1 221125_WJC_METTL3_EV_vs_WT_F07.18709.18709.3 9.49E-14 22/76 K.HNDDEQYAWESSAGGSFTVR.A "sp|P08238|HS90B_HUMAN,sp|P07900|HS90A_HUMAN,sp|Q14568|HS902_HUMAN" 3 2254.9516 0.72 104769 18709 3 2254.951046 752.6578 Heat shock protein HSP 90-beta OS=Homo sapiens OX=9606 GN=HSP90AB1 PE=1 SV=4 4.31 3071.7 - 2.57E+06 - - - -0.2248 - 3.891 0.655 - 547.9 1 2 0 -0.0005 20 0 0 0 1.73E+08 2.39E+08 - - - 9.1386 1 221125_WJC_METTL3_EV_vs_WT_F07.18710.18710.4 6.26E-06 17/144 R.FDPETNSDDAC[160.03]TYHPGVPVFHDALK[136.11].G "sp|Q9UHD1|CHRD1_HUMAN,tr|E9PL00|E9PL00_HUMAN,tr|E9PSD5|E9PSD5_HUMAN,tr|E9PIZ4|E9PIZ4_HUMAN,tr|E9PPQ5|E9PPQ5_HUMAN" 5 2839.2639 0.43 104770 18710 4 2839.256658 710.8233 Cysteine and histidine-rich domain-containing protein 1 OS=Homo sapiens OX=9606 GN=CHORDC1 PE=1 SV=2 4.34 3071.8 - 1.91E+06 - - - -2.5542 - 3.436 0.631 - 162.4 1 2 0 -0.0073 25 0 0 0 2.07E+07 4.84E+07 - - - 5.1089 0.9999 221125_WJC_METTL3_EV_vs_WT_F07.18717.18717.3 2.85E-06 16/72 R.SDK[136.11]NNEFIVIHNGIITNYK[136.11].D "sp|Q06210|GFPT1_HUMAN,tr|A0A6I8PRN4|A0A6I8PRN4_HUMAN,tr|A0A6I8PTT9|A0A6I8PTT9_HUMAN" 3 2234.1666 1.15 104775 18717 3 2234.163892 745.7295 Glutamine--fructose-6-phosphate aminotransferase [isomerizing] 1 OS=Homo sapiens OX=9606 GN=GFPT1 PE=1 SV=3 6.47 3072.7 - 2.34E+06 - - - -1.2264 - 3.355 0.512 - 270.8 1 2 1 -0.0027 19 0 0 0 6.19E+07 5.39E+07 - - - 7.2214 0.9684 221125_WJC_METTL3_EV_vs_WT_F07.18718.18718.4 3.00E-06 12/114 R.VANYC[160.03]STHLLEHITTNEDFR.A "sp|O75688|PPM1B_HUMAN,tr|B8ZZF0|B8ZZF0_HUMAN,tr|A0A3B3IS24|A0A3B3IS24_HUMAN,tr|C9JIR6|C9JIR6_HUMAN" 4 2419.1227 3.41 104776 18718 4 2420.111669 605.7879 Protein phosphatase 1B OS=Homo sapiens OX=9606 GN=PPM1B PE=1 SV=1 5.27 3072.8 - 539612 - - - 408.83 - 2.555 0.521 - 81.6 1 2 0 0.989 20 0 0 0 8.74E+06 2.56E+06 - - - 3.8004 0.9959 221125_WJC_METTL3_EV_vs_WT_F07.18720.18720.4 1.71E-05 17/138 N.SLPPATIAPPKPASWADIASKPAK.Q sp|Q9Y5A9|YTHD2_HUMAN 1 2413.3369 2 104778 18720 4 2413.334059 604.3415 YTH domain-containing family protein 2 OS=Homo sapiens OX=9606 GN=YTHDF2 PE=1 SV=2 9.7 3073.1 - 728982 - - - -1.1905 - 2.841 0.501 - 135.4 1 1 0 -0.0029 24 0 0 0 1.85E+07 9.23E+06 - - - 3.921 0.9996 221125_WJC_METTL3_EV_vs_WT_F07.18723.18723.4 0.00338 Sep-90 K.YFLHDDRDDGVDYWAK.R "sp|Q9NYF8|BCLF1_HUMAN,tr|H0YF14|H0YF14_HUMAN" 2 2013.8857 2.49 104779 18723 4 2013.885666 504.4787 Bcl-2-associated transcription factor 1 OS=Homo sapiens OX=9606 GN=BCLAF1 PE=1 SV=2 4.28 3073.4 - 261177 - - - -0.0199 - 1.71 0.441 - 53 1 2 1 0 16 0 0 0 1.23E+08 4.92E+07 - - - 3.2534 1 221125_WJC_METTL3_EV_vs_WT_F07.18725.18725.3 1.32E-16 25/96 R.SFDVNKPGC[160.03]EVDDLKGGVAGGSILK.G "sp|Q2VIR3|IF2GL_HUMAN,sp|P41091|IF2G_HUMAN" 2 2561.2796 0.8 104780 18725 3 2561.277756 854.7671 Eukaryotic translation initiation factor 2 subunit 3B OS=Homo sapiens OX=9606 GN=EIF2S3B PE=2 SV=2 4.68 3073.6 - 1.27E+06 - - - -0.7016 - 4.695 0.776 - 478.1 1 2 1 -0.0018 25 0 0 0 3.78E+07 4.74E+07 - - - 10.7491 0.9999 221125_WJC_METTL3_EV_vs_WT_F07.18727.18727.4 7.93E-09 18/126 R.SRAEAESWYQTKYEELQVTAGR.H "sp|P48668|K2C6C_HUMAN,sp|O95678|K2C75_HUMAN,sp|P02538|K2C6A_HUMAN" 3 2601.2459 41.82 104782 18727 4 2601.246448 651.3188 "Keratin, type II cytoskeletal 6C OS=Homo sapiens OX=9606 GN=KRT6C PE=1 SV=3" 4.94 3073.9 - 1.31E+06 - - - 0.1934 - 3.344 0.534 - 216.2 1 2 2 0.0005 22 0 0 0 1.62E+07 3.88E+05 - - - 4.2688 0.9999 221125_WJC_METTL3_EV_vs_WT_F07.18739.18739.4 6.94E-09 23/96 K.TDLEKDIISDTSGDFRK.L "sp|P07355|ANXA2_HUMAN,sp|A6NMY6|AXA2L_HUMAN,tr|H0YL33|H0YL33_HUMAN,tr|H0YMU9|H0YMU9_HUMAN,tr|H0YNA0|H0YNA0_HUMAN,tr|H0YM50|H0YM50_HUMAN,tr|H0YMD0|H0YMD0_HUMAN,tr|H0YMW4|H0YMW4_HUMAN,tr|H0YN42|H0YN42_HUMAN,tr|H0YN28|H0YN28_HUMAN,tr|H0YNP5|H0YNP5_HUMAN,tr|H0YNB8|H0YNB8_HUMAN,tr|H0YKS4|H0YKS4_HUMAN" 13 1938.9535 6.27 104789 18739 4 1938.952564 485.7456 Annexin A2 OS=Homo sapiens OX=9606 GN=ANXA2 PE=1 SV=2 4.36 3075.4 - 1.04E+06 - - - -0.4575 - 3.777 0.587 - 624.7 1 2 1 -0.0009 17 0 0 0 8.27E+07 1.32E+07 - - - 4.7964 1 221125_WJC_METTL3_EV_vs_WT_F07.18744.18744.3 4.61E-08 17/68 R.NHDEMSFNSGDIIQVDEK.T "sp|Q9NZM3|ITSN2_HUMAN,tr|A0A087WVF7|A0A087WVF7_HUMAN" 2 2076.9058 6.91 104792 18744 3 2076.905765 693.3092 Intersectin-2 OS=Homo sapiens OX=9606 GN=ITSN2 PE=1 SV=3 4.1 3076.1 - 420939 - - - -0.0404 - 3.542 0.631 - 434.6 1 2 0 -0.0001 18 0 0 0 9.63E+06 1.39E+06 - - - 8.7242 1 221125_WJC_METTL3_EV_vs_WT_F07.18746.18746.4 6.03E-10 29/114 K.AR[166.11]PFPDGLAEDIDK[136.11]GEVSAR[166.11].Q sp|P13639|EF2_HUMAN 1 2170.1013 0.56 104793 18746 4 2170.100115 543.5326 Elongation factor 2 OS=Homo sapiens OX=9606 GN=EEF2 PE=1 SV=4 4.44 3076.3 - 3.39E+06 - - - -0.5396 - 4.384 0.648 - 873.5 1 2 1 -0.0012 20 0 0 0 1.04E+08 1.87E+08 - - - 5.36 1 221125_WJC_METTL3_EV_vs_WT_F07.18749.18749.4 3.34E-05 18/132 K.SAMAHDPISPVLSDPHLDAVDQR.L sp|O75063|XYLK_HUMAN 1 2470.1911 1.68 104796 18749 4 2470.193989 618.555 Glycosaminoglycan xylosylkinase OS=Homo sapiens OX=9606 GN=FAM20B PE=1 SV=1 4.54 3076.7 - 616535 - - - 1.1809 - 2.949 0.472 - 133.6 1 2 0 0.0029 23 0 0 0 1.31E+07 7.78E+06 - - - 3.6839 1 221125_WJC_METTL3_EV_vs_WT_F07.18754.18754.3 7.20E-17 23/96 R.QLEDPNGSFSNAEMSELSVAQK[136.11]PEK[136.11].L "sp|Q6PJT7|ZC3HE_HUMAN,tr|H0YJA2|H0YJA2_HUMAN,tr|G3V411|G3V411_HUMAN" 3 2750.304 1.47 104799 18754 3 2750.307207 917.7753 Zinc finger CCCH domain-containing protein 14 OS=Homo sapiens OX=9606 GN=ZC3H14 PE=1 SV=1 4.25 3077.4 - 520273 - - - 1.1697 - 3.887 0.782 - 541.9 1 2 0 0.0032 25 0 0 0 2.00E+07 1.36E+07 - - - 10.3811 1 221125_WJC_METTL3_EV_vs_WT_F07.18755.18755.3 1.28E-17 25/96 R.QLEDPNGSFSNAEMSELSVAQKPEK.L "sp|Q6PJT7|ZC3HE_HUMAN,tr|H0YJA2|H0YJA2_HUMAN,tr|G3V411|G3V411_HUMAN" 3 2734.2756 1.47 104800 18755 3 2734.27602 912.4325 Zinc finger CCCH domain-containing protein 14 OS=Homo sapiens OX=9606 GN=ZC3H14 PE=1 SV=1 4.25 3077.5 - 776876 - - - 0.1573 - 4.392 0.761 - 661.1 1 2 0 0.0004 25 0 0 0 2.00E+07 1.36E+07 - - - 10.4287 0.9996 221125_WJC_METTL3_EV_vs_WT_F07.18756.18756.4 0.0966 13/96 K.APIRPDIVNFVHTNLRK.N "sp|P36578|RL4_HUMAN,tr|H3BTP7|H3BTP7_HUMAN,tr|H3BU31|H3BU31_HUMAN" 3 1989.1272 1 104801 18756 4 1989.129136 498.2891 60S ribosomal protein L4 OS=Homo sapiens OX=9606 GN=RPL4 PE=1 SV=5 10.84 3077.6 - 515053 - - - 0.9663 - 2.552 0.337 - 134.9 1 2 0 0.0019 17 0 0 0 1.28E+07 1.27E+07 - - - 2.484 0.8908 221125_WJC_METTL3_EV_vs_WT_F07.18764.18764.3 0.000317 18/124 R.LQAALDDEEAGGR[166.11]PAMEPGNGSLDLGGDSAGR[166.11].S "sp|Q00839|HNRPU_HUMAN,tr|A0A1W2PPS1|A0A1W2PPS1_HUMAN,tr|A0A1X7SBS1|A0A1X7SBS1_HUMAN" 3 3145.4485 0.02 104805 18764 3 3146.430542 1049.4901 Heterogeneous nuclear ribonucleoprotein U OS=Homo sapiens OX=9606 GN=HNRNPU PE=1 SV=6 3.9 3078.6 - 4.65E+06 - - - 312.2029 - 2.555 0.451 - 217.3 1 2 0 0.982 32 0 0 0 1.38E+05 6.36E+06 - - - 5.4543 0.9999 221125_WJC_METTL3_EV_vs_WT_F07.18766.18766.4 1.31E-08 21/144 R.SFDVNK[136.11]PGC[160.03]EVDDLK[136.11]GGVAGGSILK[136.11].G "sp|Q2VIR3|IF2GL_HUMAN,sp|P41091|IF2G_HUMAN" 2 2585.3222 0.97 104806 18766 4 2585.325939 647.3378 Eukaryotic translation initiation factor 2 subunit 3B OS=Homo sapiens OX=9606 GN=EIF2S3B PE=2 SV=2 4.68 3078.9 - 6.03E+06 - - - 1.4644 - 2.787 0.557 - 122.4 1 2 1 0.0038 25 0 0 0 1.80E+08 1.85E+08 - - - 4.3991 0.9999 221125_WJC_METTL3_EV_vs_WT_F07.18767.18767.4 3.04E-10 26/114 K.ARPFPDGLAEDIDKGEVSAR.Q sp|P13639|EF2_HUMAN 1 2142.0705 0.58 104807 18767 4 2142.073577 536.5249 Elongation factor 2 OS=Homo sapiens OX=9606 GN=EEF2 PE=1 SV=4 4.44 3078.9 - 2.01E+06 - - - 1.415 - 4.107 0.603 - 556.1 1 2 1 0.003 20 0 0 0 1.88E+08 3.22E+08 - - - 4.946 0.7704 221125_WJC_METTL3_EV_vs_WT_F07.18768.18768.3 0.0194 11/116 R.SDSPVPTAPTSGGPK[136.11]PSTASAVPELATDPE.L "sp|Q86U44|MTA70_HUMAN,tr|B4E349|B4E349_HUMAN,tr|F5H6D8|F5H6D8_HUMAN,tr|B4DTN4|B4DTN4_HUMAN" 4 2870.3913 0.17 104808 18768 3 2870.39181 957.8044 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 4.16 3079.1 - 784535 - - - 0.1853 - 1.74 0.25 - 35 1 1 0 0.0005 30 0 0 0 6.74E+06 3.90E+07 - - - 2.6014 0.9998 221125_WJC_METTL3_EV_vs_WT_F07.18769.18769.3 0.000551 17/64 K.TDLEK[136.11]DIISDTSGDFR[166.11]K[136.11].L "sp|P07355|ANXA2_HUMAN,sp|A6NMY6|AXA2L_HUMAN,tr|H0YL33|H0YL33_HUMAN,tr|H0YMU9|H0YMU9_HUMAN,tr|H0YNA0|H0YNA0_HUMAN,tr|H0YM50|H0YM50_HUMAN,tr|H0YMD0|H0YMD0_HUMAN,tr|H0YMW4|H0YMW4_HUMAN,tr|H0YN42|H0YN42_HUMAN,tr|H0YN28|H0YN28_HUMAN,tr|H0YNP5|H0YNP5_HUMAN,tr|H0YNB8|H0YNB8_HUMAN,tr|H0YKS4|H0YKS4_HUMAN" 13 1964.9901 1.27 104809 18769 3 1964.994659 656.004 Annexin A2 OS=Homo sapiens OX=9606 GN=ANXA2 PE=1 SV=2 4.36 3079.2 - 567198 - - - 2.3094 - 3.578 0.458 - 429.8 1 2 1 0.0045 17 0 0 0 1.58E+07 1.25E+07 - - - 6.8655 0.9996 221125_WJC_METTL3_EV_vs_WT_F07.18770.18770.4 0.000544 15/150 R.GALAHPGRPPPTSAALSLLPPPPPAK.K "tr|A0A669KAV7|A0A669KAV7_HUMAN,tr|M0QXA7|M0QXA7_HUMAN,tr|A0A669KBH9|A0A669KBH9_HUMAN" 3 2509.4169 1.23 104810 18770 4 2509.42245 628.3615 Protein Wiz OS=Homo sapiens OX=9606 GN=WIZ PE=1 SV=1 11 3079.3 - 188989 - - - 2.2065 - 2.259 0.378 - 64.2 1 2 0 0.0055 26 0 0 0 9.34E+06 7.58E+06 - - - 2.7716 0.9999 221125_WJC_METTL3_EV_vs_WT_F07.18772.18772.4 2.33E-10 27/150 R.TLVNKEEPPKELPAAEPVLSPLEGTK.M "sp|Q9BY77|PDIP3_HUMAN,tr|F6VRR5|F6VRR5_HUMAN" 2 2785.5113 1.75 104811 18772 4 2785.512835 697.3851 Polymerase delta-interacting protein 3 OS=Homo sapiens OX=9606 GN=POLDIP3 PE=1 SV=2 4.65 3079.5 - 5.69E+06 - - - 0.5414 - 4.281 0.609 - 435.9 1 2 2 0.0015 26 0 0 0 1.15E+09 6.58E+08 - - - 4.985 0.9997 221125_WJC_METTL3_EV_vs_WT_F07.18776.18776.4 5.98E-08 18/138 K.LYAVHQEGNK[136.11]NVGLDIEAEVPAVK[136.11].D "sp|P50990|TCPQ_HUMAN,tr|H7C2U0|H7C2U0_HUMAN" 2 2608.3832 0.76 104814 18776 4 2608.388786 653.1031 T-complex protein 1 subunit theta OS=Homo sapiens OX=9606 GN=CCT8 PE=1 SV=4 4.83 3080 - 754875 - - - 2.1542 - 2.98 0.488 - 150.4 1 2 1 0.0056 24 0 0 0 2.89E+07 3.80E+07 - - - 3.8225 0.9999 221125_WJC_METTL3_EV_vs_WT_F07.18777.18777.4 4.50E-06 21/96 K.TDLEK[136.11]DIISDTSGDFR[166.11]K[136.11].L "sp|P07355|ANXA2_HUMAN,sp|A6NMY6|AXA2L_HUMAN,tr|H0YL33|H0YL33_HUMAN,tr|H0YMU9|H0YMU9_HUMAN,tr|H0YNA0|H0YNA0_HUMAN,tr|H0YM50|H0YM50_HUMAN,tr|H0YMD0|H0YMD0_HUMAN,tr|H0YMW4|H0YMW4_HUMAN,tr|H0YN42|H0YN42_HUMAN,tr|H0YN28|H0YN28_HUMAN,tr|H0YNP5|H0YNP5_HUMAN,tr|H0YNB8|H0YNB8_HUMAN,tr|H0YKS4|H0YKS4_HUMAN" 13 1964.9901 6.25 104815 18777 4 1964.986248 492.2548 Annexin A2 OS=Homo sapiens OX=9606 GN=ANXA2 PE=1 SV=2 4.36 3080.1 - 734375 - - - -1.971 - 3.44 0.544 - 434.9 1 2 1 -0.0039 17 0 0 0 8.26E+07 1.32E+07 - - - 4.3889 1 221125_WJC_METTL3_EV_vs_WT_F07.18778.18778.3 3.36E-11 26/92 R.GHTVTEPIQPLEPELPGEGQPEAR[166.11].A sp|O15446|RPA34_HUMAN 1 2590.2903 1.04 104816 18778 3 2590.292685 864.4374 DNA-directed RNA polymerase I subunit RPA34 OS=Homo sapiens OX=9606 GN=POLR1G PE=1 SV=1 4.32 3080.2 - 704719 - - - 0.9339 - 4.237 0.652 - 579.8 1 2 0 0.0024 24 0 0 0 2.55E+07 2.44E+07 - - - 9.162 0.9958 221125_WJC_METTL3_EV_vs_WT_F07.18783.18783.4 0.00517 12/138 R.GDEDDIPLGPQSNVSLLDQHQHLK[136.11].E "sp|Q9UJV9|DDX41_HUMAN,tr|A0A499FJW5|A0A499FJW5_HUMAN,tr|D6RGI7|D6RGI7_HUMAN" 3 2662.3078 0.94 104819 18783 4 2662.324927 666.5842 Probable ATP-dependent RNA helicase DDX41 OS=Homo sapiens OX=9606 GN=DDX41 PE=1 SV=2 4.34 3080.9 - 407948 - - - 6.4245 - 2.483 0.41 - 50.2 1 2 0 0.0171 24 0 0 0 7.11E+06 7.59E+06 - - - 3.0818 0.9917 221125_WJC_METTL3_EV_vs_WT_F07.18784.18784.3 1.99E-05 13/44 D.GIHLLDPDVVAR[166.11].F sp|Q86U44|MTA70_HUMAN 1 1313.7331 0 104820 18784 3 1313.733763 438.9183 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 5.21 3081 - 222705 - - - 0.5009 - 2.597 0.379 - 329.5 1 1 0 0.0007 12 0 0 0 3.46E+04 1.16E+07 - - - 5.4106 1 221125_WJC_METTL3_EV_vs_WT_F07.18787.18787.3 4.86E-14 25/100 R.TLVNKEEPPKELPAAEPVLSPLEGTK.M "sp|Q9BY77|PDIP3_HUMAN,tr|F6VRR5|F6VRR5_HUMAN" 2 2785.5113 1.84 104822 18787 3 2785.519347 929.5111 Polymerase delta-interacting protein 3 OS=Homo sapiens OX=9606 GN=POLDIP3 PE=1 SV=2 4.65 3081.4 - 560233 - - - 2.8792 - 4.281 0.705 - 536.7 1 2 2 0.008 26 0 0 0 1.50E+08 8.17E+07 - - - 9.7434 0.9998 221125_WJC_METTL3_EV_vs_WT_F07.18792.18792.3 1.48E-05 Dec-68 K.QKGDVVLQSDHVIETLTK.T "sp|O00159|MYO1C_HUMAN,tr|F5H6E2|F5H6E2_HUMAN" 2 2009.0793 0.99 104826 18792 3 2009.082668 670.7004 Unconventional myosin-Ic OS=Homo sapiens OX=9606 GN=MYO1C PE=1 SV=4 5.38 3082 - 298328 - - - 1.6664 - 2.857 0.512 - 172.4 1 2 1 0.0033 18 0 0 0 4.18E+06 4.21E+06 - - - 6.8614 0.9999 221125_WJC_METTL3_EV_vs_WT_F07.18795.18795.4 5.17E-07 19/126 R.SLDNEWDRDYGRPLDEQESQFR.E "sp|P49750|YLPM1_HUMAN,tr|H0YIQ2|H0YIQ2_HUMAN" 2 2754.227 2.29 104827 18795 4 2754.232428 689.564 YLP motif-containing protein 1 OS=Homo sapiens OX=9606 GN=YLPM1 PE=1 SV=4 4.14 3082.4 - 954252 - - - 1.9708 - 3.048 0.582 - 99.2 1 2 1 0.0054 22 0 0 0 1.22E+07 5.34E+06 - - - 4.6549 0.9739 221125_WJC_METTL3_EV_vs_WT_F07.18797.18797.3 0.000275 13/56 K.R[166.11]GLLQDDAHPTLVTY.A "sp|Q86U44|MTA70_HUMAN,tr|F5H6D8|F5H6D8_HUMAN,tr|H0YFV6|H0YFV6_HUMAN,tr|B4DTN4|B4DTN4_HUMAN" 4 1707.882 0.4 104829 18797 3 1707.886149 570.3013 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 5.21 3082.6 - 623779 - - - 2.4563 - 2.293 0.405 - 165.5 1 1 0 0.0042 15 0 0 0 8.35E+06 2.11E+07 - - - 5.2196 0.9989 221125_WJC_METTL3_EV_vs_WT_F07.18798.18798.4 0.000169 13/102 K.QKGDVVLQSDHVIETLTK.T "sp|O00159|MYO1C_HUMAN,tr|F5H6E2|F5H6E2_HUMAN" 2 2009.0793 0.68 104830 18798 4 2009.085169 503.2771 Unconventional myosin-Ic OS=Homo sapiens OX=9606 GN=MYO1C PE=1 SV=4 5.38 3082.8 - 463993 - - - 2.9113 - 2.263 0.425 - 112.1 1 2 1 0.0058 18 0 0 0 4.60E+06 6.81E+06 - - - 3.2033 0.998 221125_WJC_METTL3_EV_vs_WT_F07.18800.18800.3 6.79E-06 19/116 K.IGNPVPYNEGLGQPQVAPPAPAASPAASSR.P "sp|P27694|RFA1_HUMAN,tr|I3L2M5|I3L2M5_HUMAN" 2 2912.4781 1.82 104832 18800 3 2912.480214 971.8333 Replication protein A 70 kDa DNA-binding subunit OS=Homo sapiens OX=9606 GN=RPA1 PE=1 SV=2 6 3083 - 429876 - - - 0.7361 - 2.989 0.546 - 201.2 1 1 0 0.0021 30 0 0 0 1.12E+07 6.17E+06 - - - 7.1458 0.9983 221125_WJC_METTL3_EV_vs_WT_F07.18801.18801.3 0.00318 Oct-68 K.QK[136.11]GDVVLQSDHVIETLTK[136.11].T "sp|O00159|MYO1C_HUMAN,tr|F5H6E2|F5H6E2_HUMAN" 2 2025.1077 0.99 104833 18801 3 2025.108003 676.0432 Unconventional myosin-Ic OS=Homo sapiens OX=9606 GN=MYO1C PE=1 SV=4 5.38 3083.2 - 404561 - - - 0.1397 - 2.103 0.328 - 122.8 1 2 1 0.0003 18 0 0 0 4.18E+06 4.21E+06 - - - 4.0479 1 221125_WJC_METTL3_EV_vs_WT_F07.18807.18807.3 9.65E-13 26/92 R.GHTVTEPIQPLEPELPGEGQPEAR.A sp|O15446|RPA34_HUMAN 1 2580.282 1.04 104837 18807 3 2580.286067 861.1013 DNA-directed RNA polymerase I subunit RPA34 OS=Homo sapiens OX=9606 GN=POLR1G PE=1 SV=1 4.32 3083.9 - 895986 - - - 1.5777 - 3.962 0.642 - 502.8 1 2 0 0.0041 24 0 0 0 2.55E+07 2.44E+07 - - - 8.8942 0.9999 221125_WJC_METTL3_EV_vs_WT_F07.18809.18809.4 1.36E-08 21/114 R.VANYC[160.03]STHLLEHITTNEDFR[166.11].A "sp|O75688|PPM1B_HUMAN,tr|B8ZZF0|B8ZZF0_HUMAN,tr|A0A3B3IS24|A0A3B3IS24_HUMAN,tr|C9JIR6|C9JIR6_HUMAN" 4 2429.1309 3.44 104839 18809 4 2429.140527 608.29 Protein phosphatase 1B OS=Homo sapiens OX=9606 GN=PPM1B PE=1 SV=1 5.27 3084.1 - 713253 - - - 3.9512 - 3.607 0.537 - 282.1 1 2 0 0.0096 20 0 0 0 5.74E+08 1.67E+08 - - - 4.3263 1 221125_WJC_METTL3_EV_vs_WT_F07.18810.18810.3 1.26E-11 25/76 R.VANYC[160.03]STHLLEHITTNEDFR.A "sp|O75688|PPM1B_HUMAN,tr|B8ZZF0|B8ZZF0_HUMAN,tr|A0A3B3IS24|A0A3B3IS24_HUMAN,tr|C9JIR6|C9JIR6_HUMAN" 4 2419.1227 3.81 104840 18810 3 2419.123578 807.3815 Protein phosphatase 1B OS=Homo sapiens OX=9606 GN=PPM1B PE=1 SV=1 5.27 3084.3 - 642619 - - - 0.3799 - 4.151 0.675 - 638.3 1 2 0 0.0009 20 0 0 0 2.70E+08 7.09E+07 - - - 9.5184 0.9983 221125_WJC_METTL3_EV_vs_WT_F07.18812.18812.3 1.37E-07 15/116 K.IGNPVPYNEGLGQPQVAPPAPAASPAASSR[166.11].P "sp|P27694|RFA1_HUMAN,tr|I3L2M5|I3L2M5_HUMAN" 2 2922.4863 1.82 104842 18812 3 2922.489033 975.1694 Replication protein A 70 kDa DNA-binding subunit OS=Homo sapiens OX=9606 GN=RPA1 PE=1 SV=2 6 3084.5 - 318927 - - - 0.9215 - 2.956 0.581 - 113.1 1 1 0 0.0027 30 0 0 0 1.12E+07 6.17E+06 - - - 7.5103 0.9788 221125_WJC_METTL3_EV_vs_WT_F07.18814.18814.3 0.000128 16/124 R.LQAALDDEEAGGRPAMEPGNGSLDLGGDSAGR.S "sp|Q00839|HNRPU_HUMAN,tr|A0A1W2PPS1|A0A1W2PPS1_HUMAN,tr|A0A1X7SBS1|A0A1X7SBS1_HUMAN" 3 3125.432 -1 104843 18814 3 3126.42111 1042.8179 Heterogeneous nuclear ribonucleoprotein U OS=Homo sapiens OX=9606 GN=HNRNPU PE=1 SV=6 3.9 3084.7 - 1.31E+07 - - - 316.4766 - 2.369 0.483 - 179 1 2 0 0.9891 32 0 0 0 0.00E+00 0.00E+00 - - - 5.6352 1 221125_WJC_METTL3_EV_vs_WT_F07.18815.18815.3 6.11E-09 35/76 K.AR[166.11]PFPDGLAEDIDK[136.11]GEVSAR[166.11].Q sp|P13639|EF2_HUMAN 1 2170.1013 0.6 104844 18815 3 2170.104744 724.3744 Elongation factor 2 OS=Homo sapiens OX=9606 GN=EEF2 PE=1 SV=4 4.44 3084.9 - 1.35E+06 - - - 1.5935 - 5.717 0.637 - 1785.1 1 2 1 0.0035 20 0 0 0 7.04E+07 1.17E+08 - - - 9.8706 0.9999 221125_WJC_METTL3_EV_vs_WT_F07.18816.18816.4 1.89E-08 23/120 R.DSFDDRGPSLNPVLDYDHGSR.S "sp|P43243|MATR3_HUMAN,tr|A8MXP9|A8MXP9_HUMAN,tr|D6R991|D6R991_HUMAN,tr|A0A0R4J2E8|A0A0R4J2E8_HUMAN,tr|D6REM6|D6REM6_HUMAN" 5 2361.0622 1.41 104845 18816 4 2361.068335 591.2728 Matrin-3 OS=Homo sapiens OX=9606 GN=MATR3 PE=1 SV=2 4.28 3084.9 - 2.70E+06 - - - 2.6128 - 3.926 0.595 - 420.3 1 2 1 0.0062 21 0 0 0 1.21E+10 8.58E+09 - - - 4.8554 0.9999 221125_WJC_METTL3_EV_vs_WT_F07.18818.18818.4 0.00118 Dec-96 K.VSVTVSDDGTLHMHFSR.N sp|Q9ULX3|NOB1_HUMAN 1 1886.8945 2.73 104847 18818 4 1886.894139 472.7309 RNA-binding protein NOB1 OS=Homo sapiens OX=9606 GN=NOB1 PE=1 SV=1 5.97 3085.2 - 271268 - - - -0.1892 - 2.022 0.412 - 75.7 1 2 0 -0.0004 17 0 0 0 2.97E+07 1.09E+07 - - - 3.0564 1 221125_WJC_METTL3_EV_vs_WT_F07.18821.18821.3 1.69E-13 26/76 R.VANYC[160.03]STHLLEHITTNEDFR[166.11].A "sp|O75688|PPM1B_HUMAN,tr|B8ZZF0|B8ZZF0_HUMAN,tr|A0A3B3IS24|A0A3B3IS24_HUMAN,tr|C9JIR6|C9JIR6_HUMAN" 4 2429.1309 3.8 104848 18821 3 2429.131629 810.7176 Protein phosphatase 1B OS=Homo sapiens OX=9606 GN=PPM1B PE=1 SV=1 5.27 3085.6 - 779306 - - - 0.2882 - 4.7 0.666 - 763.7 1 2 0 0.0007 20 0 0 0 2.69E+08 7.09E+07 - - - 9.7195 0.9999 221125_WJC_METTL3_EV_vs_WT_F07.18827.18827.4 1.07E-08 21/96 K.VSVTVSDDGTLHMHFSR[166.11].N sp|Q9ULX3|NOB1_HUMAN 1 1896.9028 1.83 104854 18827 4 1896.908104 475.233 RNA-binding protein NOB1 OS=Homo sapiens OX=9606 GN=NOB1 PE=1 SV=1 5.97 3086.3 - 529164 - - - 2.8141 - 3.714 0.514 - 428.1 1 2 0 0.0053 17 0 0 0 1.67E+07 9.15E+06 - - - 4.1539 0.9999 221125_WJC_METTL3_EV_vs_WT_F07.18828.18828.3 0.00235 Nov-76 K.MQTDK[136.11]PFDQTTISLQMGTNK[136.11].G "sp|Q15417|CNN3_HUMAN,tr|E9PDU6|E9PDU6_HUMAN" 2 2299.1159 0.39 104855 18828 3 2299.112059 767.3792 Calponin-3 OS=Homo sapiens OX=9606 GN=CNN3 PE=1 SV=1 5.71 3086.5 - 462874 - - - -1.6785 - 2.399 0.418 - 113.6 1 2 0 -0.0039 20 0 0 0 2.51E+06 6.41E+06 - - - 5.3221 0.8631 221125_WJC_METTL3_EV_vs_WT_F07.18830.18830.4 0.121 Jul-96 K.GQK[136.11]C[160.03]EFQDAYVLLSEK[136.11]K[136.11].L "sp|P10809|CH60_HUMAN,tr|A0A7I2V2X6|A0A7I2V2X6_HUMAN,tr|A0A7I2YQK6|A0A7I2YQK6_HUMAN,tr|A0A7I2V599|A0A7I2V599_HUMAN,tr|A0A7I2YQ71|A0A7I2YQ71_HUMAN,tr|A0A7I2V5M1|A0A7I2V5M1_HUMAN,tr|A0A7I2V5K3|A0A7I2V5K3_HUMAN,tr|A0A7I2V369|A0A7I2V369_HUMAN" 8 2066.0569 1.81 104857 18830 4 2066.056653 517.5215 "60 kDa heat shock protein, mitochondrial OS=Homo sapiens OX=9606 GN=HSPD1 PE=1 SV=2" 6.17 3086.7 - 324603 - - - -0.1084 - 1.505 0.154 - 42.9 1 2 1 -0.0002 17 0 0 0 4.53E+06 2.50E+06 - - - 0.7083 1 221125_WJC_METTL3_EV_vs_WT_F07.18831.18831.3 7.36E-08 15/96 R.ISTPQTNTVPIK[136.11]PLISTPPVSSQPK[136.11].V "sp|Q9BTA9|WAC_HUMAN,tr|A0A7P0T961|A0A7P0T961_HUMAN,tr|A0A0A0MRT2|A0A0A0MRT2_HUMAN,tr|J3QTA0|J3QTA0_HUMAN" 4 2645.4975 2.38 104858 18831 3 2645.498805 882.8398 WW domain-containing adapter protein with coiled-coil OS=Homo sapiens OX=9606 GN=WAC PE=1 SV=3 10 3086.9 - 218661 - - - 0.5054 - 2.679 0.586 - 82.3 1 2 0 0.0013 25 0 0 0 1.24E+08 5.22E+07 - - - 7.3401 0.9999 221125_WJC_METTL3_EV_vs_WT_F07.18833.18833.4 5.06E-05 22/150 R.TLVNK[136.11]EEPPK[136.11]ELPAAEPVLSPLEGTK[136.11].M "sp|Q9BY77|PDIP3_HUMAN,tr|F6VRR5|F6VRR5_HUMAN" 2 2809.5539 1.75 104859 18833 4 2809.557311 703.3958 Polymerase delta-interacting protein 3 OS=Homo sapiens OX=9606 GN=POLDIP3 PE=1 SV=2 4.65 3087.1 - 2.19E+06 - - - 1.2045 - 3.856 0.567 - 289.5 1 2 2 0.0034 26 0 0 0 1.15E+09 6.58E+08 - - - 4.586 0.9999 221125_WJC_METTL3_EV_vs_WT_F07.18835.18835.4 3.48E-11 25/120 K.FEK[136.11]DFDFESANAQFNK[136.11]EEIDR[166.11].E "sp|Q8ND56|LS14A_HUMAN,tr|A0A140TA76|A0A140TA76_HUMAN,tr|K7EMZ9|K7EMZ9_HUMAN" 3 2604.1979 1.05 104860 18835 4 2604.196353 652.0567 Protein LSM14 homolog A OS=Homo sapiens OX=9606 GN=LSM14A PE=1 SV=3 4.2 3087.3 - 9.56E+06 - - - -0.5871 - 4.714 0.604 - 644.5 1 2 2 -0.0015 21 0 0 0 2.75E+08 2.63E+08 - - - 4.9955 0.9999 221125_WJC_METTL3_EV_vs_WT_F07.18836.18836.4 1.97E-13 29/120 K.FEKDFDFESANAQFNKEEIDR.E "sp|Q8ND56|LS14A_HUMAN,tr|A0A140TA76|A0A140TA76_HUMAN,tr|K7EMZ9|K7EMZ9_HUMAN" 3 2578.1612 1.05 104861 18836 4 2578.160297 645.5476 Protein LSM14 homolog A OS=Homo sapiens OX=9606 GN=LSM14A PE=1 SV=3 4.2 3087.3 - 7.80E+06 - - - -0.3549 - 4.177 0.591 - 874.7 1 2 2 -0.0009 21 0 0 0 2.76E+08 2.63E+08 - - - 4.8425 1 221125_WJC_METTL3_EV_vs_WT_F07.18837.18837.3 7.25E-05 18/72 R.HPHDIIDDINSGAVEC[160.03]PAS.- sp|P30050|RL12_HUMAN 1 2045.9113 - 104862 18837 3 2045.909962 682.9777 60S ribosomal protein L12 OS=Homo sapiens OX=9606 GN=RPL12 PE=1 SV=1 4.21 3087.4 - 1.77E+06 - - - -0.6388 - 3.45 0.561 - 456.1 1 2 0 -0.0013 19 0 0 0 - - - - - 7.8367 0.9996 221125_WJC_METTL3_EV_vs_WT_F07.18838.18838.4 7.16E-05 15/114 K.QSTWEKPDDLKTPAEQLLSK.C "sp|O75400|PR40A_HUMAN,tr|F5H578|F5H578_HUMAN,tr|H0YG38|H0YG38_HUMAN,tr|A0A7N4I394|A0A7N4I394_HUMAN" 4 2313.1852 1.14 104863 18838 4 2313.18623 579.3036 Pre-mRNA-processing factor 40 homolog A OS=Homo sapiens OX=9606 GN=PRPF40A PE=1 SV=2 4.78 3087.6 - 1.32E+06 - - - 0.4271 - 2.669 0.418 - 138.2 1 2 1 0.001 20 0 0 0 4.43E+07 3.91E+07 - - - 3.1922 1 221125_WJC_METTL3_EV_vs_WT_F07.18839.18839.3 1.20E-05 22/64 K.VSVTVSDDGTLHMHFSR.N sp|Q9ULX3|NOB1_HUMAN 1 1886.8945 0.63 104864 18839 3 1886.894559 629.9721 RNA-binding protein NOB1 OS=Homo sapiens OX=9606 GN=NOB1 PE=1 SV=1 5.97 3087.7 - 1.17E+06 - - - 0.0334 - 3.517 0.564 - 351 1 2 0 0.0001 17 0 0 0 1.00E+07 1.59E+07 - - - 8.0051 0.9999 221125_WJC_METTL3_EV_vs_WT_F07.18844.18844.4 0.000136 22/120 R.DSFDDR[166.11]GPSLNPVLDYDHGSR[166.11].S "sp|P43243|MATR3_HUMAN,tr|A8MXP9|A8MXP9_HUMAN,tr|D6R991|D6R991_HUMAN,tr|A0A0R4J2E8|A0A0R4J2E8_HUMAN,tr|D6REM6|D6REM6_HUMAN" 5 2381.0787 1.41 104868 18844 4 2381.07718 596.277 Matrin-3 OS=Homo sapiens OX=9606 GN=MATR3 PE=1 SV=2 4.28 3088.2 - 1.10E+08 - - - -0.6409 - 3.772 0.513 - 372.3 1 2 1 -0.0015 21 0 0 0 1.21E+10 8.58E+09 - - - 4.1297 1 221125_WJC_METTL3_EV_vs_WT_F07.18846.18846.3 6.43E-11 29/80 R.DSFDDR[166.11]GPSLNPVLDYDHGSR[166.11].S "sp|P43243|MATR3_HUMAN,tr|A8MXP9|A8MXP9_HUMAN,tr|D6R991|D6R991_HUMAN,tr|A0A0R4J2E8|A0A0R4J2E8_HUMAN,tr|D6REM6|D6REM6_HUMAN" 5 2381.0787 1.42 104869 18846 3 2381.07335 794.7002 Matrin-3 OS=Homo sapiens OX=9606 GN=MATR3 PE=1 SV=2 4.28 3088.5 - 2.74E+07 - - - -2.2494 - 4.045 0.659 - 889.2 1 2 1 -0.0054 21 0 0 0 3.44E+09 2.43E+09 - - - 9.2361 1 221125_WJC_METTL3_EV_vs_WT_F07.18847.18847.3 4.93E-10 22/96 R.ISTPQTNTVPIKPLISTPPVSSQPK.V "sp|Q9BTA9|WAC_HUMAN,tr|A0A7P0T961|A0A7P0T961_HUMAN,tr|A0A0A0MRT2|A0A0A0MRT2_HUMAN,tr|J3QTA0|J3QTA0_HUMAN" 4 2629.4691 2.38 104870 18847 3 2629.467032 877.497 WW domain-containing adapter protein with coiled-coil OS=Homo sapiens OX=9606 GN=WAC PE=1 SV=3 10 3088.6 - 1.74E+06 - - - -0.7743 - 3.706 0.599 - 262.4 1 2 0 -0.002 25 0 0 0 1.24E+08 5.22E+07 - - - 8.2314 1 221125_WJC_METTL3_EV_vs_WT_F07.18848.18848.3 3.75E-12 29/80 K.FEKDFDFESANAQFNKEEIDR.E "sp|Q8ND56|LS14A_HUMAN,tr|A0A140TA76|A0A140TA76_HUMAN,tr|K7EMZ9|K7EMZ9_HUMAN" 3 2578.1612 0.95 104871 18848 3 2578.154296 860.3943 Protein LSM14 homolog A OS=Homo sapiens OX=9606 GN=LSM14A PE=1 SV=3 4.2 3088.7 - 2.33E+06 - - - -2.6825 - 4.496 0.713 - 778.3 1 2 2 -0.0069 21 0 0 0 4.98E+07 5.21E+07 - - - 10.0912 0.9893 221125_WJC_METTL3_EV_vs_WT_F07.18850.18850.4 0.0202 12/114 K.QSTWEK[136.11]PDDLK[136.11]TPAEQLLSK[136.11].C "sp|O75400|PR40A_HUMAN,tr|F5H578|F5H578_HUMAN,tr|H0YG38|H0YG38_HUMAN,tr|A0A7N4I394|A0A7N4I394_HUMAN" 4 2337.2278 1.13 104873 18850 4 2337.225984 585.3142 Pre-mRNA-processing factor 40 homolog A OS=Homo sapiens OX=9606 GN=PRPF40A PE=1 SV=2 4.78 3088.9 - 1.50E+06 - - - -0.795 - 1.618 0.26 - 58.3 1 2 1 -0.0019 20 0 0 0 4.41E+07 3.89E+07 - - - 1.6494 1 221125_WJC_METTL3_EV_vs_WT_F07.18854.18854.3 8.59E-16 34/80 K.FEK[136.11]DFDFESANAQFNK[136.11]EEIDR[166.11].E "sp|Q8ND56|LS14A_HUMAN,tr|A0A140TA76|A0A140TA76_HUMAN,tr|K7EMZ9|K7EMZ9_HUMAN" 3 2604.1979 0.95 104875 18854 3 2604.19264 869.0732 Protein LSM14 homolog A OS=Homo sapiens OX=9606 GN=LSM14A PE=1 SV=3 4.2 3089.4 - 3.08E+06 - - - -2.0129 - 5.553 0.736 - 1899.3 1 2 2 -0.0052 21 0 0 0 4.98E+07 5.21E+07 - - - 10.8543 0.9936 221125_WJC_METTL3_EV_vs_WT_F07.18855.18855.2 2.41E-06 13/40 R.DSFDDR[166.11]GPSLNPVLDYDHGSR[166.11].S "sp|P43243|MATR3_HUMAN,tr|A8MXP9|A8MXP9_HUMAN,tr|D6R991|D6R991_HUMAN,tr|A0A0R4J2E8|A0A0R4J2E8_HUMAN,tr|D6REM6|D6REM6_HUMAN" 5 2381.0787 1.71 104876 18855 2 2381.070685 1191.5466 Matrin-3 OS=Homo sapiens OX=9606 GN=MATR3 PE=1 SV=2 4.28 3089.6 - 1.30E+06 - - - -3.3686 - 2.219 0.58 - 150.8 1 2 1 -0.008 21 0 0 0 1.36E+08 7.93E+07 - - - 5.282 1 221125_WJC_METTL3_EV_vs_WT_F07.18858.18858.3 2.60E-08 32/72 S.FDDRGPSLNPVLDYDHGSR.S "sp|P43243|MATR3_HUMAN,tr|A8MXP9|A8MXP9_HUMAN,tr|D6R991|D6R991_HUMAN,tr|A0A0R4J2E8|A0A0R4J2E8_HUMAN,tr|D6REM6|D6REM6_HUMAN" 5 2159.0032 0.57 104877 18858 3 2158.993258 720.675 Matrin-3 OS=Homo sapiens OX=9606 GN=MATR3 PE=1 SV=2 4.56 3090 - 1.25E+06 - - - -4.6026 - 4.999 0.603 - 1163.3 1 1 1 -0.0099 19 0 0 0 5.22E+07 9.14E+07 - - - 9.2137 1 221125_WJC_METTL3_EV_vs_WT_F07.18860.18860.2 4.86E-09 20/40 R.DSFDDRGPSLNPVLDYDHGSR.S "sp|P43243|MATR3_HUMAN,tr|A8MXP9|A8MXP9_HUMAN,tr|D6R991|D6R991_HUMAN,tr|A0A0R4J2E8|A0A0R4J2E8_HUMAN,tr|D6REM6|D6REM6_HUMAN" 5 2361.0622 1.71 104878 18860 2 2361.056205 1181.5384 Matrin-3 OS=Homo sapiens OX=9606 GN=MATR3 PE=1 SV=2 4.28 3090.2 - 2.21E+06 - - - -2.5247 - 2.849 0.678 - 375.4 1 2 1 -0.006 21 0 0 0 1.36E+08 7.93E+07 - - - 6.6209 0.9999 221125_WJC_METTL3_EV_vs_WT_F07.18868.18868.3 3.03E-09 21/84 K.QTIGNSC[160.03]GTIGLIHAVANNQDK[136.11].L "sp|P09936|UCHL1_HUMAN,tr|D6R956|D6R956_HUMAN,tr|D6RE83|D6RE83_HUMAN,tr|D6R974|D6R974_HUMAN" 4 2318.1528 0.84 104883 18868 3 2318.142175 773.7249 Ubiquitin carboxyl-terminal hydrolase isozyme L1 OS=Homo sapiens OX=9606 GN=UCHL1 PE=1 SV=2 6.73 3091 - 1.09E+06 - - - -4.6019 - 3.837 0.562 - 575.9 1 2 0 -0.0107 22 0 0 0 1.77E+07 2.12E+07 - - - 7.9908 1 221125_WJC_METTL3_EV_vs_WT_F07.18877.18877.2 8.79E-10 17/34 K.PSTASAVPELATDPELEK[136.11].K "sp|Q86U44|MTA70_HUMAN,tr|B4E349|B4E349_HUMAN,tr|F5H6D8|F5H6D8_HUMAN,tr|H0YFV6|H0YFV6_HUMAN,tr|B4DTN4|B4DTN4_HUMAN" 5 1861.94 0.001 104888 18877 2 1861.932913 931.9773 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 4 3092.1 - 1.28E+06 - - - -3.8272 - 3.189 0.594 - 534.4 1 1 0 -0.0071 18 0 0 0 0.00E+00 3.23E+07 - - - 6.2772 0.9997 221125_WJC_METTL3_EV_vs_WT_F07.18879.18879.3 0.0016 19/80 R.DSFDDR[166.11]GPSLNPVLDYDHGSR.S "sp|P43243|MATR3_HUMAN,tr|A8MXP9|A8MXP9_HUMAN,tr|D6R991|D6R991_HUMAN,tr|A0A0R4J2E8|A0A0R4J2E8_HUMAN,tr|D6REM6|D6REM6_HUMAN" 5 2371.0704 - 104889 18879 3 2371.063969 791.3641 Matrin-3 OS=Homo sapiens OX=9606 GN=MATR3 PE=1 SV=2 4.28 3092.3 - 1.86E+06 - - - -2.7275 - 3.435 0.475 - 395.7 1 2 1 -0.0065 21 0 0 0 - - - - - 6.7925 1 221125_WJC_METTL3_EV_vs_WT_F07.18885.18885.2 4.24E-07 13/20 L.NPVLDYDHGSR.S "sp|P43243|MATR3_HUMAN,tr|A8MXP9|A8MXP9_HUMAN,tr|D6R991|D6R991_HUMAN,tr|A0A0R4J2E8|A0A0R4J2E8_HUMAN,tr|D6REM6|D6REM6_HUMAN" 5 1271.5895 2.66 104893 18885 2 1271.590764 636.802 Matrin-3 OS=Homo sapiens OX=9606 GN=MATR3 PE=1 SV=2 5.21 3093 - 956030 - - - 1.0223 - 2.55 0.615 - 806.9 1 1 0 0.0013 11 0 0 0 2.91E+07 1.10E+07 - - - 6.1153 1 221125_WJC_METTL3_EV_vs_WT_F07.18892.18892.3 9.37E-11 33/68 F.DDRGPSLNPVLDYDHGSR.S "sp|P43243|MATR3_HUMAN,tr|A8MXP9|A8MXP9_HUMAN,tr|D6R991|D6R991_HUMAN,tr|A0A0R4J2E8|A0A0R4J2E8_HUMAN,tr|D6REM6|D6REM6_HUMAN" 5 2011.9348 1.78 104896 18892 3 2011.934215 671.6522 Matrin-3 OS=Homo sapiens OX=9606 GN=MATR3 PE=1 SV=2 4.56 3093.9 - 1.66E+06 - - - -0.2813 - 4.664 0.696 - 1442.8 1 1 1 -0.0006 18 0 0 0 3.57E+07 2.00E+07 - - - 10.134 0.9999 221125_WJC_METTL3_EV_vs_WT_F07.18893.18893.4 1.08E-08 25/150 K.TFPTVNPTTGEVIGHVAEGDR[166.11]ADVDR[166.11].A "sp|P30837|AL1B1_HUMAN,tr|A0A0U1RQK9|A0A0U1RQK9_HUMAN" 2 2772.3582 1.88 104897 18893 4 2772.353509 694.0968 "Aldehyde dehydrogenase X, mitochondrial OS=Homo sapiens OX=9606 GN=ALDH1B1 PE=1 SV=3" 4.43 3094 - 1.59E+06 - - - -1.6834 - 3.908 0.512 - 281.8 1 2 1 -0.0047 26 0 0 0 4.22E+07 2.24E+07 - - - 4.1111 0.9997 221125_WJC_METTL3_EV_vs_WT_F07.18896.18896.4 8.46E-09 26/180 R.VPTHTLAMVVPPQEPDRTSQENSPALLGVQK.G "sp|Q8IWZ3|ANKH1_HUMAN,tr|E9PDP5|E9PDP5_HUMAN,tr|H7C2F5|H7C2F5_HUMAN" 3 3338.7293 3.16 104898 18896 4 3338.721224 835.6896 Ankyrin repeat and KH domain-containing protein 1 OS=Homo sapiens OX=9606 GN=ANKHD1 PE=1 SV=1 5.44 3094.4 - 1.84E+06 - - - -2.4117 - 3.923 0.473 - 273.7 1 2 1 -0.0081 31 0 0 0 4.83E+07 1.53E+07 - - - 3.7562 0.9999 221125_WJC_METTL3_EV_vs_WT_F07.18900.18900.4 3.43E-07 28/150 K.TFPTVNPTTGEVIGHVAEGDRADVDR.A "sp|P30837|AL1B1_HUMAN,tr|A0A0U1RQK9|A0A0U1RQK9_HUMAN" 2 2752.3416 1.88 104900 18900 4 2752.340362 689.0927 "Aldehyde dehydrogenase X, mitochondrial OS=Homo sapiens OX=9606 GN=ALDH1B1 PE=1 SV=3" 4.43 3094.8 - 2.00E+06 - - - -0.4629 - 3.775 0.557 - 394.1 1 2 1 -0.0013 26 0 0 0 4.22E+07 2.24E+07 - - - 4.4928 1 221125_WJC_METTL3_EV_vs_WT_F07.18905.18905.3 2.54E-14 31/92 K.VGPNATYNFSQSLNANDLANSRPK.T sp|Q9Y5V3|MAGD1_HUMAN 1 2577.2572 1.6 104902 18905 3 2577.258818 860.093 Melanoma-associated antigen D1 OS=Homo sapiens OX=9606 GN=MAGED1 PE=1 SV=3 8.56 3095.4 - 3.41E+06 - - - 0.6363 - 4.344 0.691 - 706.5 1 2 0 0.0016 24 0 0 0 1.35E+08 8.45E+07 - - - 9.6549 0.9992 221125_WJC_METTL3_EV_vs_WT_F07.18911.18911.3 0.00167 Dec-44 R.YLYTLVITDK[136.11]EK[136.11].A "sp|P63173|RL38_HUMAN,tr|J3KT73|J3KT73_HUMAN,tr|J3QL01|J3QL01_HUMAN" 3 1500.841 1.14 104905 18911 3 1500.843041 501.2876 60S ribosomal protein L38 OS=Homo sapiens OX=9606 GN=RPL38 PE=1 SV=2 6.07 3096.3 - 566806 - - - 1.3286 - 1.989 0.406 - 118.3 1 2 1 0.002 12 0 0 0 2.11E+07 1.86E+07 - - - 4.972 0.9994 221125_WJC_METTL3_EV_vs_WT_F07.18917.18917.3 4.03E-05 Dec-44 R.YLYTLVITDKEK.A "sp|P63173|RL38_HUMAN,tr|J3KT73|J3KT73_HUMAN,tr|J3QL01|J3QL01_HUMAN" 3 1484.8126 1.14 104909 18917 3 1484.809104 495.9448 60S ribosomal protein L38 OS=Homo sapiens OX=9606 GN=RPL38 PE=1 SV=2 6.07 3097.1 - 677280 - - - -2.3862 - 2.106 0.469 - 129.8 1 2 1 -0.0035 12 0 0 0 2.11E+07 1.86E+07 - - - 5.8324 1 221125_WJC_METTL3_EV_vs_WT_F07.18918.18918.3 3.16E-10 22/96 K.QLESLWSDSPAPPGPQAGPPSRPPR.Y "sp|Q8WUF5|IASPP_HUMAN,tr|K7EN03|K7EN03_HUMAN" 2 2623.3143 6.09 104910 18918 3 2623.317591 875.4454 RelA-associated inhibitor OS=Homo sapiens OX=9606 GN=PPP1R13L PE=1 SV=4 6.07 3097.2 - 1.98E+06 - - - 1.2549 - 3.256 0.646 - 424.6 1 2 0 0.0033 25 0 0 0 3.83E+07 6.28E+06 - - - 8.4573 0.9999 221125_WJC_METTL3_EV_vs_WT_F07.18919.18919.3 1.00E-05 14/52 K.YEK[136.11]EK[136.11]FEEMIQQIK[136.11].E "sp|P48643|TCPE_HUMAN,tr|E9PCA1|E9PCA1_HUMAN,tr|B7ZAR1|B7ZAR1_HUMAN,tr|E7ENZ3|E7ENZ3_HUMAN" 4 1865.9659 0.73 104911 18919 3 1865.963569 622.9959 T-complex protein 1 subunit epsilon OS=Homo sapiens OX=9606 GN=CCT5 PE=1 SV=1 4.95 3097.3 - 1.73E+06 - - - -1.269 - 3.214 0.467 - 169.3 1 2 2 -0.0024 14 0 0 0 5.13E+07 7.04E+07 - - - 6.8486 1 221125_WJC_METTL3_EV_vs_WT_F07.18921.18921.3 1.24E-11 19/52 K.YEKEKFEEMIQQIK.E "sp|P48643|TCPE_HUMAN,tr|E9PCA1|E9PCA1_HUMAN,tr|B7ZAR1|B7ZAR1_HUMAN,tr|E7ENZ3|E7ENZ3_HUMAN" 4 1841.9233 0.73 104913 18921 3 1841.922582 614.9817 T-complex protein 1 subunit epsilon OS=Homo sapiens OX=9606 GN=CCT5 PE=1 SV=1 4.95 3097.5 - 630974 - - - -0.4099 - 3.106 0.617 - 259.7 1 2 2 -0.0008 14 0 0 0 5.13E+07 7.04E+07 - - - 8.4306 0.9999 221125_WJC_METTL3_EV_vs_WT_F07.18922.18922.4 2.41E-06 14/108 R.LKVGLQVVAVKAPGFGDNR.K "sp|P10809|CH60_HUMAN,tr|A0A7I2V2X6|A0A7I2V2X6_HUMAN,tr|A0A7I2YQK6|A0A7I2YQK6_HUMAN,tr|A0A7I2V599|A0A7I2V599_HUMAN,tr|A0A7I2V5M1|A0A7I2V5M1_HUMAN" 5 1967.1316 1.99 104914 18922 4 1967.131699 492.7902 "60 kDa heat shock protein, mitochondrial OS=Homo sapiens OX=9606 GN=HSPD1 PE=1 SV=2" 9.99 3097.6 - 355900 - - - 0.0351 - 2.936 0.587 - 118.7 1 2 2 0.0001 19 0 0 0 9.11E+06 4.57E+06 - - - 4.6996 0.9998 221125_WJC_METTL3_EV_vs_WT_F07.18929.18929.4 6.18E-05 13/78 K.YEKEKFEEMIQQIK.E "sp|P48643|TCPE_HUMAN,tr|E9PCA1|E9PCA1_HUMAN,tr|B7ZAR1|B7ZAR1_HUMAN,tr|E7ENZ3|E7ENZ3_HUMAN" 4 1841.9233 0.62 104919 18929 4 1841.92333 461.4881 T-complex protein 1 subunit epsilon OS=Homo sapiens OX=9606 GN=CCT5 PE=1 SV=1 4.95 3098.4 - 866974 - - - -0.0038 - 2.197 0.481 - 124.7 1 2 2 0 14 0 0 0 3.18E+07 5.14E+07 - - - 3.6991 1 221125_WJC_METTL3_EV_vs_WT_F07.18931.18931.3 7.08E-12 15/96 R.EVEEELATSGGQSPTGEQIPQFQQR.Q "sp|Q9UPN3|MACF1_HUMAN,tr|A0A804HL78|A0A804HL78_HUMAN,tr|H3BQK9|H3BQK9_HUMAN,tr|A0A7P0MQR8|A0A7P0MQR8_HUMAN,tr|H0Y390|H0Y390_HUMAN,tr|H3BPE1|H3BPE1_HUMAN,tr|A0A590UJG2|A0A590UJG2_HUMAN" 7 2744.2889 2.64 104921 18931 3 2744.289227 915.7703 "Microtubule-actin cross-linking factor 1, isoforms 1\2\3\5 OS=Homo sapiens OX=9606 GN=MACF1 PE=1 SV=4" 3.98 3098.7 - 559247 - - - 0.1075 - 3.551 0.653 - 107.9 1 2 0 0.0003 25 0 0 0 5.94E+06 2.25E+06 - - - 8.7357 1 221125_WJC_METTL3_EV_vs_WT_F07.18932.18932.3 3.89E-07 15/52 R.KIDQHTLLQSIVNR.T sp|Q8NDV7|TNR6A_HUMAN 1 1663.937 2.78 104922 18932 3 1663.937562 555.6529 Trinucleotide repeat-containing gene 6A protein OS=Homo sapiens OX=9606 GN=TNRC6A PE=1 SV=2 8.75 3098.8 - 529092 - - - 0.366 - 3.102 0.469 - 465.5 1 2 0 0.0006 14 0 0 0 1.00E+07 3.61E+06 - - - 6.7772 0.9999 221125_WJC_METTL3_EV_vs_WT_F07.18933.18933.4 0.00536 19/120 R.KVETDHIVAAVGLEPNVELAK.T "sp|O95831|AIFM1_HUMAN,tr|A0A6Q8PFA7|A0A6Q8PFA7_HUMAN,tr|A0A6Q8PHJ9|A0A6Q8PHJ9_HUMAN,tr|A0A6Q8PFS4|A0A6Q8PFS4_HUMAN,tr|E9PMA0|E9PMA0_HUMAN,tr|A0A7I2PK44|A0A7I2PK44_HUMAN,tr|A0A6Q8PG15|A0A6Q8PG15_HUMAN,tr|A0A6Q8PFE1|A0A6Q8PFE1_HUMAN,tr|A0A7I2RLJ8|A0A7I2RLJ8_HUMAN,tr|A0A6Q8PFQ8|A0A6Q8PFQ8_HUMAN,tr|A0A6Q8PHC0|A0A6Q8PHC0_HUMAN,tr|A0A6Q8PFM5|A0A6Q8PFM5_HUMAN" 12 2231.2161 1.24 104923 18933 4 2231.217267 558.8113 "Apoptosis-inducing factor 1, mitochondrial OS=Homo sapiens OX=9606 GN=AIFM1 PE=1 SV=1" 4.83 3098.9 - 469678 - - - 0.5015 - 2.957 0.423 - 217.9 1 2 0 0.0011 21 0 0 0 7.47E+06 6.03E+06 - - - 3.266 0.9997 221125_WJC_METTL3_EV_vs_WT_F07.18937.18937.4 0.00023 12/102 K.LTLSALLDGKNVNAGGHK.L sp|P21796|VDAC1_HUMAN 1 1806.9952 2.03 104925 18937 4 1806.99445 452.7561 Voltage-dependent anion-selective channel protein 1 OS=Homo sapiens OX=9606 GN=VDAC1 PE=1 SV=2 8.6 3099.5 - 416444 - - - -0.4128 - 2.412 0.436 - 91.5 1 2 1 -0.0007 18 0 0 0 7.19E+06 3.55E+06 - - - 3.3223 0.9305 221125_WJC_METTL3_EV_vs_WT_F07.18950.18950.3 0.17 13/64 K.K[136.11]LHEEEIQELQAQIQEQ.H "sp|P08670|VIME_HUMAN,tr|B0YJC5|B0YJC5_HUMAN,tr|B0YJC4|B0YJC4_HUMAN" 3 2100.0579 2.28 104934 18950 3 2100.060317 701.0266 Vimentin OS=Homo sapiens OX=9606 GN=VIM PE=1 SV=4 4.32 3101.1 - 663617 - - - 1.1685 - 2.434 0.261 - 111.4 1 1 0 0.0025 17 0 0 0 1.76E+07 7.70E+06 - - - 3.6965 0.9999 221125_WJC_METTL3_EV_vs_WT_F07.18956.18956.4 8.29E-05 20/120 K.K[136.11]EVEQFDVATHLQTAPELVDR[166.11].V sp|Q9Y3A2|UTP11_HUMAN 1 2442.251 3.57 104938 18956 4 2442.244262 611.57 Probable U3 small nucleolar RNA-associated protein 11 OS=Homo sapiens OX=9606 GN=UTP11 PE=1 SV=2 4.5 3101.9 - 765084 - - - -2.7483 - 2.961 0.454 - 260.9 1 2 0 -0.0067 21 0 0 0 2.51E+07 7.02E+06 - - - 3.5347 1 221125_WJC_METTL3_EV_vs_WT_F07.18980.18980.3 6.63E-13 26/88 R.TGDFQLHTNVNDGTEFGGSIYQK[136.11].V "sp|P45880|VDAC2_HUMAN,tr|A0A0A0MR02|A0A0A0MR02_HUMAN" 2 2535.1757 1.72 104952 18980 3 2535.175405 846.0659 Voltage-dependent anion-selective channel protein 2 OS=Homo sapiens OX=9606 GN=VDAC2 PE=1 SV=2 4.53 3104.8 - 1.91E+06 - - - -0.1345 - 5.046 0.719 - 693.5 1 2 0 -0.0003 23 0 0 0 7.38E+07 4.30E+07 - - - 10.3532 0.9963 221125_WJC_METTL3_EV_vs_WT_F07.18986.18986.4 0.39 12/108 R.GLLQDDAHPTLVTYADHSK[136.11].L "sp|Q86U44|MTA70_HUMAN,tr|F5H6D8|F5H6D8_HUMAN,tr|H0YFV6|H0YFV6_HUMAN,tr|B4DTN4|B4DTN4_HUMAN" 4 2088.0367 0.01 104956 18986 4 2088.036594 523.0165 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 5.13 3105.6 - 1.31E+06 - - - -0.0666 - 2.109 0.236 - 63.5 1 2 0 -0.0001 19 0 0 0 1.92E+05 2.28E+07 - - - 1.5325 0.9964 221125_WJC_METTL3_EV_vs_WT_F07.18987.18987.4 2.39E-08 17/90 P.SELFAQHIVTIVHHVK.E "sp|Q9Y2W1|TR150_HUMAN,tr|A0A3B3ITZ9|A0A3B3ITZ9_HUMAN" 2 1857.0261 3 104957 18987 4 1857.026089 465.2638 Thyroid hormone receptor-associated protein 3 OS=Homo sapiens OX=9606 GN=THRAP3 PE=1 SV=2 6.78 3105.7 - 2.23E+06 - - - -0.0075 - 2.964 0.51 - 176.6 1 1 0 0 16 0 0 0 5.70E+07 1.90E+07 - - - 4.0478 1 221125_WJC_METTL3_EV_vs_WT_F07.18993.18993.3 3.61E-11 26/88 R.TGDFQLHTNVNDGTEFGGSIYQK.V "sp|P45880|VDAC2_HUMAN,tr|A0A0A0MR02|A0A0A0MR02_HUMAN" 2 2527.1615 1.72 104960 18993 3 2527.16433 843.3945 Voltage-dependent anion-selective channel protein 2 OS=Homo sapiens OX=9606 GN=VDAC2 PE=1 SV=2 4.53 3106.4 - 2.11E+06 - - - 1.1016 - 4.857 0.663 - 606.7 1 2 0 0.0028 23 0 0 0 7.38E+07 4.30E+07 - - - 9.6386 0.9841 221125_WJC_METTL3_EV_vs_WT_F07.19008.19008.3 0.0103 Dec-44 K.QKVDSLLENLEK.L "sp|P0DMR1|HNRC4_HUMAN,sp|P07910|HNRPC_HUMAN,sp|O60812|HNRC1_HUMAN,sp|B2RXH8|HNRC2_HUMAN,sp|B7ZW38|HNRC3_HUMAN,tr|B4DY08|B4DY08_HUMAN,tr|G3V5V7|G3V5V7_HUMAN,tr|B2R5W2|B2R5W2_HUMAN,tr|G3V4C1|G3V4C1_HUMAN,tr|A0A0G2JPF8|A0A0G2JPF8_HUMAN,tr|A0A0G2JNQ3|A0A0G2JNQ3_HUMAN,tr|G3V576|G3V576_HUMAN,tr|G3V2D6|G3V2D6_HUMAN,tr|G3V4W0|G3V4W0_HUMAN,tr|G3V2Q1|G3V2Q1_HUMAN" 15 1414.7668 1.53 104967 19008 3 1414.764563 472.5962 Heterogeneous nuclear ribonucleoprotein C-like 4 OS=Homo sapiens OX=9606 GN=HNRNPCL4 PE=3 SV=1 4.68 3108.2 - 1.73E+06 - - - -1.5529 - 1.965 0.201 - 177.9 1 2 1 -0.0022 12 0 0 0 5.72E+07 3.75E+07 - - - 2.6527 0.9464 221125_WJC_METTL3_EV_vs_WT_F07.19021.19021.3 7.00E-08 27/88 K.QSK[136.11]PVTTPEEIAQVATISANGDK[136.11].E "sp|P10809|CH60_HUMAN,tr|A0A7I2V599|A0A7I2V599_HUMAN,tr|E7EXB4|E7EXB4_HUMAN,tr|A0A7I2YQ71|A0A7I2YQ71_HUMAN,tr|E7ESH4|E7ESH4_HUMAN,tr|A0A7I2V5M1|A0A7I2V5M1_HUMAN,tr|A0A7I2V5K3|A0A7I2V5K3_HUMAN,tr|A0A7I2V369|A0A7I2V369_HUMAN" 8 2399.2515 1.4 104974 19021 3 2400.235222 800.7578 "60 kDa heat shock protein, mitochondrial OS=Homo sapiens OX=9606 GN=HSPD1 PE=1 SV=2" 4.68 3109.8 - 1.48E+06 - - - 410.0187 - 3.503 0.548 - 730.8 1 2 0 0.9837 23 0 0 0 4.43E+09 3.17E+09 - - - 7.3181 0.9999 221125_WJC_METTL3_EV_vs_WT_F07.19023.19023.3 6.55E-09 18/56 K.AAVEWFDGK[136.11]DFQGSK[136.11].L "sp|Q01844|EWS_HUMAN,tr|B0QYK0|B0QYK0_HUMAN,tr|H7BY36|H7BY36_HUMAN,tr|A0A0D9SFL3|A0A0D9SFL3_HUMAN,tr|C9JGE3|C9JGE3_HUMAN" 5 1699.8177 0.22 104976 19023 3 1699.815316 567.6132 RNA-binding protein EWS OS=Homo sapiens OX=9606 GN=EWSR1 PE=1 SV=1 4.56 3110 - 1.49E+06 - - - -1.3943 - 3.621 0.551 - 469.8 1 2 1 -0.0024 15 0 0 0 1.09E+07 4.87E+07 - - - 8.0401 0.9982 221125_WJC_METTL3_EV_vs_WT_F07.19036.19036.3 2.97E-09 17/124 K.LQSAAQSVPSGAGVPATTASSSFAYGISHHPS.A sp|Q15643|TRIPB_HUMAN 1 3069.4792 - 104985 19036 3 3069.482494 1024.167 Thyroid receptor-interacting protein 11 OS=Homo sapiens OX=9606 GN=TRIP11 PE=1 SV=3 6.92 3111.5 - 535522 - - - 1.0758 - 3.072 0.571 - 158.9 1 1 0 0.0033 32 0 0 0 - - - - - 7.4872 1 221125_WJC_METTL3_EV_vs_WT_F07.19038.19038.3 3.52E-10 15/96 M.PAHLLQDDISSSYTTTTTITAPPSR.V sp|O00767|SCD_HUMAN 1 2672.3293 1.61 104987 19038 3 2672.325231 891.7837 Stearoyl-CoA desaturase OS=Homo sapiens OX=9606 GN=SCD PE=1 SV=2 5.22 3111.8 - 709297 - - - -1.5376 - 3.524 0.684 - 163.5 1 2 0 -0.0041 25 0 0 0 8.93E+06 5.56E+06 - - - 9.0627 1 221125_WJC_METTL3_EV_vs_WT_F07.19042.19042.3 1.14E-12 24/96 R.HGGGGGGFGGGGFGSRSLVGLGGTK.S sp|P35908|K22E_HUMAN 1 2132.0511 -1 104989 19042 3 2133.034012 711.691 "Keratin, type II cytoskeletal 2 epidermal OS=Homo sapiens OX=9606 GN=KRT2 PE=1 SV=2" 11 3112.3 - 1.30E+06 - - - 460.9946 - 4.642 0.691 - 644.9 1 2 1 0.9829 25 0 0 0 0.00E+00 0.00E+00 - - - 9.5035 0.9918 221125_WJC_METTL3_EV_vs_WT_F07.19046.19046.3 1.07E-06 20/68 Q.HVQIDVDVSKPDLTAALR.D "sp|P08670|VIME_HUMAN,tr|B0YJC5|B0YJC5_HUMAN,tr|B0YJC4|B0YJC4_HUMAN" 3 1976.0691 3.01 104992 19046 3 1976.075842 659.697 Vimentin OS=Homo sapiens OX=9606 GN=VIM PE=1 SV=4 5.3 3112.7 - 363699 - - - 3.4169 - 3.28 0.538 - 383.9 1 1 0 0.0068 18 0 0 0 5.13E+06 1.71E+06 - - - 7.4941 1 221125_WJC_METTL3_EV_vs_WT_F07.19050.19050.3 4.22E-07 19/112 K.TPETVVPAAPELQPSTSTDQPVTPEPTSR.A sp|Q14676|MDC1_HUMAN 1 3031.4986 2.58 104994 19050 3 3031.508136 1011.5068 Mediator of DNA damage checkpoint protein 1 OS=Homo sapiens OX=9606 GN=MDC1 PE=1 SV=3 4 3113.3 - 845619 - - - 3.1489 - 3.895 0.636 - 290 1 2 0 0.0095 29 0 0 0 1.38E+07 5.33E+06 - - - 8.7563 1 221125_WJC_METTL3_EV_vs_WT_F07.19052.19052.4 5.59E-07 16/102 K.EIEGEEIEIVLAK[136.11]PPDK[136.11]K[136.11].R "sp|O43390|HNRPR_HUMAN,tr|B4DT28|B4DT28_HUMAN,tr|A0A6Q8PH35|A0A6Q8PH35_HUMAN,tr|A0A286YEZ8|A0A286YEZ8_HUMAN" 4 2060.1467 1.94 104996 19052 4 2060.148438 516.044 Heterogeneous nuclear ribonucleoprotein R OS=Homo sapiens OX=9606 GN=HNRNPR PE=1 SV=1 4.42 3113.5 - 351885 - - - 0.8252 - 2.103 0.568 - 113.5 1 2 0 0.0017 18 0 0 0 2.00E+07 1.03E+07 - - - 4.424 0.9991 221125_WJC_METTL3_EV_vs_WT_F07.19053.19053.4 4.57E-07 16/84 K.HKELAPYDENWFYTR.A "sp|P39019|RS19_HUMAN,tr|M0R140|M0R140_HUMAN,tr|M0R2L9|M0R2L9_HUMAN,tr|M0QYF7|M0QYF7_HUMAN" 4 1967.9166 1.08 104997 19053 4 1967.923712 492.9864 40S ribosomal protein S19 OS=Homo sapiens OX=9606 GN=RPS19 PE=1 SV=2 5.45 3113.6 - 324220 - - - 3.6079 - 2.438 0.473 - 196.8 1 2 1 0.0071 15 0 0 0 1.42E+08 1.31E+08 - - - 3.6599 1 221125_WJC_METTL3_EV_vs_WT_F07.19056.19056.3 3.91E-11 18/56 K.HKELAPYDENWFYTR.A "sp|P39019|RS19_HUMAN,tr|M0R140|M0R140_HUMAN,tr|M0R2L9|M0R2L9_HUMAN,tr|M0QYF7|M0QYF7_HUMAN" 4 1967.9166 1.08 104998 19056 3 1967.919022 656.9795 40S ribosomal protein S19 OS=Homo sapiens OX=9606 GN=RPS19 PE=1 SV=2 5.45 3114 - 769690 - - - 1.2246 - 3.346 0.614 - 573.1 1 2 1 0.0024 15 0 0 0 2.35E+08 2.17E+08 - - - 8.5363 0.9999 221125_WJC_METTL3_EV_vs_WT_F07.19058.19058.4 3.60E-07 18/84 K.HK[136.11]ELAPYDENWFYTR[166.11].A "sp|P39019|RS19_HUMAN,tr|M0R140|M0R140_HUMAN,tr|M0R2L9|M0R2L9_HUMAN,tr|M0QYF7|M0QYF7_HUMAN" 4 1985.9391 1.08 105000 19058 4 1985.940891 497.492 40S ribosomal protein S19 OS=Homo sapiens OX=9606 GN=RPS19 PE=1 SV=2 5.45 3114.3 - 742813 - - - 0.9109 - 2.942 0.56 - 221 1 2 1 0.0018 15 0 0 0 1.41E+08 1.31E+08 - - - 4.4858 1 221125_WJC_METTL3_EV_vs_WT_F07.19065.19065.3 4.62E-06 18/56 K.HK[136.11]ELAPYDENWFYTR[166.11].A "sp|P39019|RS19_HUMAN,tr|M0R140|M0R140_HUMAN,tr|M0R2L9|M0R2L9_HUMAN,tr|M0QYF7|M0QYF7_HUMAN" 4 1985.9391 1.08 105005 19065 3 1985.941033 662.987 40S ribosomal protein S19 OS=Homo sapiens OX=9606 GN=RPS19 PE=1 SV=2 5.45 3115.2 - 2.16E+06 - - - 0.9824 - 3.378 0.598 - 522.5 1 2 1 0.002 15 0 0 0 2.32E+08 2.14E+08 - - - 8.3829 0.9877 221125_WJC_METTL3_EV_vs_WT_F07.19067.19067.4 0.00116 22/168 L.TTVGWDHQVVHHVVPTEPLPAPGPASVTE.- "sp|Q9BQA1|MEP50_HUMAN,tr|H0Y711|H0Y711_HUMAN" 2 3056.5356 - 105007 19067 4 3056.541764 765.1412 Methylosome protein 50 OS=Homo sapiens OX=9606 GN=WDR77 PE=1 SV=1 5.29 3115.4 - 1.33E+06 - - - 2.0216 - 3.554 0.442 - 240.3 1 1 0 0.0062 29 0 0 0 - - - - - 3.4623 1 221125_WJC_METTL3_EV_vs_WT_F07.19068.19068.4 2.01E-12 21/114 K.DKLESEMEDAYHEHQANLLR.Q "sp|P23246|SFPQ_HUMAN,tr|H0Y9K7|H0Y9K7_HUMAN" 2 2427.1125 0.82 105008 19068 4 2427.113199 607.7854 "Splicing factor, proline- and glutamine-rich OS=Homo sapiens OX=9606 GN=SFPQ PE=1 SV=2" 4.63 3115.6 - 1.31E+06 - - - 0.2929 - 4.45 0.705 - 528.5 1 2 1 0.0007 20 0 0 0 7.37E+07 9.05E+07 - - - 5.8612 0.9853 221125_WJC_METTL3_EV_vs_WT_F07.19069.19069.4 0.165 13/144 R.VGTVIGSNK[136.11]LEQMPSK[136.11]EDAIEHFMK[136.11].L "sp|P09874|PARP1_HUMAN,tr|A0A7I2V3E1|A0A7I2V3E1_HUMAN" 2 2811.4361 0.69 105009 19069 4 2811.436678 703.8663 Poly [ADP-ribose] polymerase 1 OS=Homo sapiens OX=9606 GN=PARP1 PE=1 SV=4 5.53 3115.7 - 764689 - - - 0.1924 - 2.364 0.233 - 72.8 1 2 2 0.0005 25 0 0 0 2.17E+07 3.15E+07 - - - 1.5276 1 221125_WJC_METTL3_EV_vs_WT_F07.19076.19076.3 2.87E-09 Nov-96 M.PAHLLQDDISSSYTTTTTITAPPSR[166.11].V sp|O00767|SCD_HUMAN 1 2682.3376 1.59 105016 19076 3 2682.342501 895.1198 Stearoyl-CoA desaturase OS=Homo sapiens OX=9606 GN=SCD PE=1 SV=2 5.22 3116.6 - 246354 - - - 1.8234 - 2.658 0.642 - 79.8 1 2 0 0.0049 25 0 0 0 8.83E+06 5.56E+06 - - - 7.9454 1 221125_WJC_METTL3_EV_vs_WT_F07.19078.19078.3 4.30E-10 22/80 K.TQTVC[160.03]NFTDGALVQHQEWDGK.E "sp|Q01469|FABP5_HUMAN,sp|A8MUU1|FB5L3_HUMAN,tr|I6L8B7|I6L8B7_HUMAN" 3 2433.1019 125.12 105017 19078 3 2433.102986 812.0413 Fatty acid-binding protein 5 OS=Homo sapiens OX=9606 GN=FABP5 PE=1 SV=3 4.53 3116.9 - 1.42E+06 - - - 0.4369 - 4.618 0.69 - 541.1 1 2 0 0.0011 21 0 0 0 4.57E+08 3.66E+06 - - - 9.9005 0.9986 221125_WJC_METTL3_EV_vs_WT_F07.19085.19085.3 3.98E-08 14/112 L.TTVGWDHQVVHHVVPTEPLPAPGPASVTE.- "sp|Q9BQA1|MEP50_HUMAN,tr|H0Y711|H0Y711_HUMAN" 2 3056.5356 - 105023 19085 3 3056.535669 1019.8525 Methylosome protein 50 OS=Homo sapiens OX=9606 GN=WDR77 PE=1 SV=1 5.29 3117.8 - 274473 - - - 0.0275 - 3.012 0.593 - 132.2 1 1 0 0.0001 29 0 0 0 - - - - - 7.688 0.9999 221125_WJC_METTL3_EV_vs_WT_F07.19089.19089.4 1.29E-06 19/120 R.DSFDDRGPSLNPVLDYDHGSR.S "sp|P43243|MATR3_HUMAN,tr|A8MXP9|A8MXP9_HUMAN,tr|D6R991|D6R991_HUMAN,tr|A0A0R4J2E8|A0A0R4J2E8_HUMAN,tr|D6REM6|D6REM6_HUMAN" 5 2361.0622 1.22 105025 19089 4 2361.06435 591.2728 Matrin-3 OS=Homo sapiens OX=9606 GN=MATR3 PE=1 SV=2 4.28 3118.3 - 1.41E+06 - - - 0.925 - 3.394 0.547 - 229.9 1 2 1 0.0022 21 0 0 0 1.85E+07 1.52E+07 - - - 4.3905 1 221125_WJC_METTL3_EV_vs_WT_F07.19090.19090.4 1.79E-06 20/144 R.SRPPEERPPGLPLPPPPPSSSAVFR.L sp|P48634|PRC2A_HUMAN 1 2663.4184 2.17 105026 19090 4 2663.421661 666.8619 Protein PRRC2A OS=Homo sapiens OX=9606 GN=PRRC2A PE=1 SV=3 9.23 3118.4 - 606613 - - - 1.2356 - 3.414 0.487 - 141.9 1 2 0 0.0033 25 0 0 0 1.54E+07 7.11E+06 - - - 3.8546 1 221125_WJC_METTL3_EV_vs_WT_F07.19091.19091.4 2.71E-12 24/114 K.DK[136.11]LESEMEDAYHEHQANLLR[166.11].Q "sp|P23246|SFPQ_HUMAN,tr|H0Y9K7|H0Y9K7_HUMAN" 2 2445.135 0.84 105027 19091 4 2445.137122 612.291 "Splicing factor, proline- and glutamine-rich OS=Homo sapiens OX=9606 GN=SFPQ PE=1 SV=2" 4.63 3118.5 - 4.50E+06 - - - 0.885 - 4.642 0.702 - 671.5 1 2 1 0.0022 20 0 0 0 7.50E+07 8.97E+07 - - - 5.8488 0.9998 221125_WJC_METTL3_EV_vs_WT_F07.19093.19093.2 1.08E-06 13/26 R.VPTANVSVVDLTC[160.03]R[166.11].L "sp|P04406|G3P_HUMAN,tr|E7EUT5|E7EUT5_HUMAN" 2 1539.7954 1.05 105029 19093 2 1539.797662 770.905 Glyceraldehyde-3-phosphate dehydrogenase OS=Homo sapiens OX=9606 GN=GAPDH PE=1 SV=3 5.8 3118.8 - 462193 - - - 1.4379 - 2.902 0.497 - 562.1 1 2 0 0.0022 14 0 0 0 7.64E+06 7.28E+06 - - - 5.3847 0.9999 221125_WJC_METTL3_EV_vs_WT_F07.19095.19095.4 3.06E-07 18/120 R.DSFDDR[166.11]GPSLNPVLDYDHGSR[166.11].S "sp|P43243|MATR3_HUMAN,tr|A8MXP9|A8MXP9_HUMAN,tr|D6R991|D6R991_HUMAN,tr|A0A0R4J2E8|A0A0R4J2E8_HUMAN,tr|D6REM6|D6REM6_HUMAN" 5 2381.0787 1.23 105030 19095 4 2381.079706 596.277 Matrin-3 OS=Homo sapiens OX=9606 GN=MATR3 PE=1 SV=2 4.28 3119 - 1.07E+06 - - - 0.42 - 2.84 0.542 - 96.3 1 2 1 0.001 21 0 0 0 1.99E+07 1.62E+07 - - - 4.2884 1 221125_WJC_METTL3_EV_vs_WT_F07.19097.19097.3 0.00936 19/72 K.QGAPTSFLPPEASQLKPDR.Q "sp|Q9BUJ2|HNRL1_HUMAN,tr|M0R0K8|M0R0K8_HUMAN,tr|M0QYZ0|M0QYZ0_HUMAN,tr|A0A0A0MRA5|A0A0A0MRA5_HUMAN,tr|M0QZV6|M0QZV6_HUMAN,tr|B7Z4B8|B7Z4B8_HUMAN,tr|M0QYI8|M0QYI8_HUMAN,tr|M0R203|M0R203_HUMAN" 8 2038.0484 1.64 105031 19097 3 2038.051653 680.3567 Heterogeneous nuclear ribonucleoprotein U-like protein 1 OS=Homo sapiens OX=9606 GN=HNRNPUL1 PE=1 SV=2 6.07 3119.2 - 763210 - - - 1.6187 - 3.3 0.504 - 312.2 1 2 0 0.0033 19 0 0 0 4.53E+07 2.76E+07 - - - 7.0914 1 221125_WJC_METTL3_EV_vs_WT_F07.19099.19099.4 1.97E-11 26/138 K.VHSPSGALEEC[160.03]YVTEIDQDKYAVR.F "sp|P21333|FLNA_HUMAN,tr|A0A7P0NMY4|A0A7P0NMY4_HUMAN,tr|Q60FE5|Q60FE5_HUMAN" 3 2765.2967 2.54 105033 19099 4 2765.297786 692.3314 Filamin-A OS=Homo sapiens OX=9606 GN=FLNA PE=1 SV=4 4.5 3119.5 - 862232 - - - 0.4072 - 5.09 0.648 - 607.7 1 2 1 0.0011 24 0 0 0 8.89E+06 3.50E+06 - - - 5.3882 0.9985 221125_WJC_METTL3_EV_vs_WT_F07.19100.19100.4 0.000195 14/126 K.LGIQTDDK[136.11]GHIIVDEFQNTNVK[136.11].G sp|P00390|GSHR_HUMAN 1 2499.294 0.47 105034 19100 4 2499.29901 625.8308 "Glutathione reductase, mitochondrial OS=Homo sapiens OX=9606 GN=GSR PE=1 SV=2" 4.66 3119.6 - 734917 - - - 1.9978 - 2.891 0.359 - 127.9 1 2 1 0.005 22 0 0 0 8.78E+06 1.87E+07 - - - 2.6967 0.9966 221125_WJC_METTL3_EV_vs_WT_F07.19101.19101.2 2.19E-05 28-Aug K.HK[136.11]ELAPYDENWFYTR[166.11].A "sp|P39019|RS19_HUMAN,tr|M0R140|M0R140_HUMAN,tr|M0R2L9|M0R2L9_HUMAN,tr|M0QYF7|M0QYF7_HUMAN" 4 1985.9391 1.25 105035 19101 2 1985.935415 993.9768 40S ribosomal protein S19 OS=Homo sapiens OX=9606 GN=RPS19 PE=1 SV=2 5.45 3119.7 - 160002 - - - -1.8465 - 1.961 0.504 - 138.7 1 2 1 -0.0037 15 0 0 0 3.93E+06 3.14E+06 - - - 4.4181 0.9999 221125_WJC_METTL3_EV_vs_WT_F07.19104.19104.4 1.20E-06 23/144 R.VGTVIGSNKLEQMPSKEDAIEHFMK.L "sp|P09874|PARP1_HUMAN,tr|A0A7I2V3E1|A0A7I2V3E1_HUMAN" 2 2787.3935 0.75 105036 19104 4 2787.395431 697.8557 Poly [ADP-ribose] polymerase 1 OS=Homo sapiens OX=9606 GN=PARP1 PE=1 SV=4 5.53 3120.1 - 1.39E+06 - - - 0.6795 - 4.46 0.482 - 285.9 1 2 2 0.0019 25 0 0 0 2.17E+07 2.89E+07 - - - 3.8964 1 221125_WJC_METTL3_EV_vs_WT_F07.19107.19107.3 3.27E-09 19/72 K.QGAPTSFLPPEASQLK[136.11]PDR[166.11].Q "sp|Q9BUJ2|HNRL1_HUMAN,tr|M0R0K8|M0R0K8_HUMAN,tr|M0QYZ0|M0QYZ0_HUMAN,tr|A0A0A0MRA5|A0A0A0MRA5_HUMAN,tr|M0QZV6|M0QZV6_HUMAN,tr|B7Z4B8|B7Z4B8_HUMAN,tr|M0QYI8|M0QYI8_HUMAN,tr|M0R203|M0R203_HUMAN" 8 2056.0708 1.64 105039 19107 3 2056.073538 686.3642 Heterogeneous nuclear ribonucleoprotein U-like protein 1 OS=Homo sapiens OX=9606 GN=HNRNPUL1 PE=1 SV=2 6.07 3120.5 - 604867 - - - 1.32 - 3.554 0.55 - 276.6 1 2 0 0.0027 19 0 0 0 4.37E+07 2.66E+07 - - - 7.7866 0.9999 221125_WJC_METTL3_EV_vs_WT_F07.19109.19109.4 1.77E-05 13/90 K.R[166.11]GFAFVTFDDHDSVDK[136.11].L "sp|Q32P51|RA1L2_HUMAN,sp|P09651|ROA1_HUMAN,tr|A0A7I2YQX9|A0A7I2YQX9_HUMAN,tr|F8VZ49|F8VZ49_HUMAN,tr|A0A7I2V3R8|A0A7I2V3R8_HUMAN,tr|F8VTQ5|F8VTQ5_HUMAN,tr|F8W6I7|F8W6I7_HUMAN,tr|H0YH80|H0YH80_HUMAN,tr|A0A7I2V2L6|A0A7I2V2L6_HUMAN,tr|A0A7I2V3W0|A0A7I2V3W0_HUMAN,tr|A0A7I2V5U9|A0A7I2V5U9_HUMAN,tr|A0A2R8Y4L2|A0A2R8Y4L2_HUMAN" 12 1872.8761 1.2 105041 19109 4 1872.881645 469.2263 Heterogeneous nuclear ribonucleoprotein A1-like 2 OS=Homo sapiens OX=9606 GN=HNRNPA1L2 PE=2 SV=2 4.56 3120.8 - 277528 - - - 2.9356 - 2.262 0.561 - 127.5 1 2 0 0.0055 16 0 0 0 9.43E+06 7.88E+06 - - - 4.395 1 221125_WJC_METTL3_EV_vs_WT_F07.19112.19112.4 2.05E-07 16/90 K.RGFAFVTFDDHDSVDK.L "sp|Q32P51|RA1L2_HUMAN,sp|P09651|ROA1_HUMAN,tr|A0A7I2YQX9|A0A7I2YQX9_HUMAN,tr|F8VZ49|F8VZ49_HUMAN,tr|A0A7I2V3R8|A0A7I2V3R8_HUMAN,tr|F8VTQ5|F8VTQ5_HUMAN,tr|F8W6I7|F8W6I7_HUMAN,tr|H0YH80|H0YH80_HUMAN,tr|A0A7I2V2L6|A0A7I2V2L6_HUMAN,tr|A0A7I2V3W0|A0A7I2V3W0_HUMAN,tr|A0A7I2V5U9|A0A7I2V5U9_HUMAN,tr|A0A2R8Y4L2|A0A2R8Y4L2_HUMAN" 12 1854.8537 1.2 105042 19112 4 1854.85554 464.7207 Heterogeneous nuclear ribonucleoprotein A1-like 2 OS=Homo sapiens OX=9606 GN=HNRNPA1L2 PE=2 SV=2 4.56 3121.2 - 493283 - - - 1.0044 - 2.737 0.572 - 235.3 1 2 0 0.0019 16 0 0 0 9.43E+06 7.84E+06 - - - 4.5588 0.9419 221125_WJC_METTL3_EV_vs_WT_F07.19113.19113.4 4.02E-08 17/162 K.LGDLKEEGDVMDKTNGLPVQNGIDADVK.D "sp|Q14671|PUM1_HUMAN,tr|Q5T1Z8|Q5T1Z8_HUMAN,tr|H0YEH2|H0YEH2_HUMAN,tr|Q5T1Z4|Q5T1Z4_HUMAN" 4 2969.4652 0.15 105043 19113 4 2970.454048 743.3736 Pumilio homolog 1 OS=Homo sapiens OX=9606 GN=PUM1 PE=1 SV=3 4.09 3121.3 - 702465 - - - 333.0115 - 3.468 0.513 - 165.5 1 2 2 0.9889 28 0 0 0 5.61E+06 3.72E+07 - - - 3.8033 0.9993 221125_WJC_METTL3_EV_vs_WT_F07.19115.19115.4 0.000119 12/126 K.LGIQTDDKGHIIVDEFQNTNVK.G sp|P00390|GSHR_HUMAN 1 2483.2656 0.42 105045 19115 4 2483.270667 621.8237 "Glutathione reductase, mitochondrial OS=Homo sapiens OX=9606 GN=GSR PE=1 SV=2" 4.66 3121.4 - 834046 - - - 2.0336 - 2.624 0.41 - 99.8 1 2 1 0.005 22 0 0 0 7.77E+06 1.85E+07 - - - 3.1089 0.9999 221125_WJC_METTL3_EV_vs_WT_F07.19116.19116.3 7.23E-06 17/84 K.LGIQTDDK[136.11]GHIIVDEFQNTNVK[136.11].G sp|P00390|GSHR_HUMAN 1 2499.294 0.35 105046 19116 3 2499.296337 834.1053 "Glutathione reductase, mitochondrial OS=Homo sapiens OX=9606 GN=GSR PE=1 SV=2" 4.66 3121.6 - 546622 - - - 0.9283 - 3.324 0.502 - 322.7 1 2 1 0.0023 22 0 0 0 1.85E+06 5.31E+06 - - - 6.9839 1 221125_WJC_METTL3_EV_vs_WT_F07.19120.19120.4 3.28E-08 19/126 R.R[166.11]IEESAIDEVVVTNTIPHEVQK[136.11].L "sp|O60256|KPRB_HUMAN,tr|I3L0S1|I3L0S1_HUMAN" 2 2523.33 0.92 105048 19120 4 2523.333397 631.8398 Phosphoribosyl pyrophosphate synthase-associated protein 2 OS=Homo sapiens OX=9606 GN=PRPSAP2 PE=1 SV=1 4.57 3122.1 - 800972 - - - 1.3653 - 3.474 0.548 - 233.4 1 2 0 0.0034 22 0 0 0 1.15E+07 1.25E+07 - - - 4.4023 1 221125_WJC_METTL3_EV_vs_WT_F07.19123.19123.3 5.72E-11 17/80 K.LK[136.11]QQEC[160.03]PEC[160.03]DVLSLGTYSASR[166.11].S sp|Q10469|MGAT2_HUMAN 1 2458.1587 1.59 105051 19123 3 2458.158258 820.3935 "Alpha-1,6-mannosyl-glycoprotein 2-beta-N-acetylglucosaminyltransferase OS=Homo sapiens OX=9606 GN=MGAT2 PE=1 SV=1" 4.68 3122.5 - 624179 - - - -0.192 - 3.51 0.665 - 194.3 1 2 1 -0.0005 21 0 0 0 3.27E+07 2.06E+07 - - - 8.9642 1 221125_WJC_METTL3_EV_vs_WT_F07.19124.19124.3 1.53E-09 24/80 R.TQTQRPNLIGLTSGDMDVNPR.A "sp|Q9P2N5|RBM27_HUMAN,tr|U3KPZ7|U3KPZ7_HUMAN" 2 2312.1543 0.75 105052 19124 3 2312.154384 771.7254 RNA-binding protein 27 OS=Homo sapiens OX=9606 GN=RBM27 PE=1 SV=2 5.63 3122.6 - 609966 - - - 0.0394 - 4.076 0.646 - 486.7 1 2 0 0.0001 21 0 0 0 8.10E+06 1.08E+07 - - - 9.1109 1 221125_WJC_METTL3_EV_vs_WT_F07.19127.19127.2 1.64E-18 20/46 Y.SYGGGSGGGFSASSLGGGFGGGSR.G sp|P35527|K1C9_HUMAN 1 2021.8827 999 105055 19127 2 2021.8862 1011.9486 "Keratin, type I cytoskeletal 9 OS=Homo sapiens OX=9606 GN=KRT9 PE=1 SV=3" 8.46 3123 - 470232 - - - 1.7088 - 3.864 0.66 - 990.5 1 1 0 0.0035 24 0 0 0 8.22E+06 0.00E+00 - - - 7.2379 0.9995 221125_WJC_METTL3_EV_vs_WT_F07.19128.19128.4 8.00E-06 14/114 K.SFPK[136.11]DDPSK[136.11]PVHLTAFLGYK[136.11].A "sp|P39023|RL3_HUMAN,tr|H7C3M2|H7C3M2_HUMAN,tr|F8WCR1|F8WCR1_HUMAN,tr|H7C422|H7C422_HUMAN" 4 2270.2162 0.11 105056 19128 4 2270.219419 568.5613 60S ribosomal protein L3 OS=Homo sapiens OX=9606 GN=RPL3 PE=1 SV=2 8.18 3123.1 - 361890 - - - 1.4377 - 2.589 0.412 - 67 1 2 1 0.0033 20 0 0 0 5.57E+05 5.21E+06 - - - 3.1292 0.9936 221125_WJC_METTL3_EV_vs_WT_F07.19129.19129.3 2.08E-09 19/92 K.PREPFDLGEPEQSNGGFPC[160.03]TTAPK.L sp|Q99961|SH3G1_HUMAN 1 2630.2071 1.67 105057 19129 3 2630.21091 877.743 Endophilin-A2 OS=Homo sapiens OX=9606 GN=SH3GL1 PE=1 SV=1 4.41 3123.3 - 347417 - - - 1.4421 - 3.177 0.644 - 174.9 1 1 1 0.0038 24 0 0 0 5.84E+06 3.50E+06 - - - 8.4037 1 221125_WJC_METTL3_EV_vs_WT_F07.19133.19133.3 2.74E-07 17/64 K.GQPSNKEDVDDLVSQLR.Q sp|P12270|TPR_HUMAN 1 1898.9334 3.58 105059 19133 3 1898.935547 633.9851 Nucleoprotein TPR OS=Homo sapiens OX=9606 GN=TPR PE=1 SV=3 4.23 3123.8 - 1.23E+06 - - - 1.1391 - 3.531 0.645 - 446.2 1 2 1 0.0022 17 0 0 0 1.45E+08 4.06E+07 - - - 8.9176 1 221125_WJC_METTL3_EV_vs_WT_F07.19134.19134.3 9.64E-10 21/88 K.QSKPVTTPEEIAQVATISANGDK.E "sp|P10809|CH60_HUMAN,tr|A0A7I2V599|A0A7I2V599_HUMAN,tr|E7EXB4|E7EXB4_HUMAN,tr|A0A7I2YQ71|A0A7I2YQ71_HUMAN,tr|E7ESH4|E7ESH4_HUMAN,tr|A0A7I2V5M1|A0A7I2V5M1_HUMAN,tr|A0A7I2V5K3|A0A7I2V5K3_HUMAN,tr|A0A7I2V369|A0A7I2V369_HUMAN" 8 2383.2231 1.39 105060 19134 3 2383.219553 795.415 "60 kDa heat shock protein, mitochondrial OS=Homo sapiens OX=9606 GN=HSPD1 PE=1 SV=2" 4.68 3123.8 - 9.85E+06 - - - -1.4816 - 3.908 0.587 - 458.5 1 2 0 -0.0035 23 0 0 0 4.44E+09 3.19E+09 - - - 8.2811 0.9999 221125_WJC_METTL3_EV_vs_WT_F07.19135.19135.4 9.37E-05 19/120 R.YSK[136.11]EEEMDDMDR[166.11]DLGDEYGWK[136.11].Q "sp|Q9HD45|TM9S3_HUMAN,tr|Q5TB53|Q5TB53_HUMAN" 2 2636.0893 1.51 105061 19135 4 2636.09023 660.0296 Transmembrane 9 superfamily member 3 OS=Homo sapiens OX=9606 GN=TM9SF3 PE=1 SV=2 3.97 3123.9 - 1.08E+06 - - - 0.3456 - 3.24 0.563 - 382.4 1 2 2 0.0009 21 0 0 0 4.92E+07 3.26E+07 - - - 4.5148 0.9999 221125_WJC_METTL3_EV_vs_WT_F07.19137.19137.3 3.58E-05 16/64 K.GQPSNK[136.11]EDVDDLVSQLR[166.11].Q sp|P12270|TPR_HUMAN 1 1916.9559 3.59 105063 19137 3 1916.958828 639.9926 Nucleoprotein TPR OS=Homo sapiens OX=9606 GN=TPR PE=1 SV=3 4.23 3124.2 - 538066 - - - 1.5514 - 3.482 0.572 - 319.5 1 2 1 0.003 17 0 0 0 1.46E+08 4.06E+07 - - - 8.0682 1 221125_WJC_METTL3_EV_vs_WT_F07.19138.19138.4 5.69E-06 17/120 R.SSADQEEPLPHELRPLPVLSR.T sp|O60318|GANP_HUMAN 1 2369.2339 2.57 105064 19138 4 2369.236039 593.3158 Germinal-center associated nuclear protein OS=Homo sapiens OX=9606 GN=MCM3AP PE=1 SV=2 4.83 3124.3 - 417036 - - - 0.8931 - 3.031 0.522 - 165.6 1 2 0 0.0021 21 0 0 0 3.79E+07 1.47E+07 - - - 4.1355 1 221125_WJC_METTL3_EV_vs_WT_F07.19141.19141.3 1.02E-18 18/68 K.HWDQDDDFEFTGSHLTVR[166.11].N "sp|O60341|KDM1A_HUMAN,tr|R4GMQ1|R4GMQ1_HUMAN" 2 2213.9642 1.29 105067 19141 3 2213.96053 738.9953 Lysine-specific histone demethylase 1A OS=Homo sapiens OX=9606 GN=KDM1A PE=1 SV=2 4.34 3124.7 - 319843 - - - -1.6486 - 4.053 0.783 - 529.3 1 2 0 -0.0037 18 0 0 0 1.01E+07 7.84E+06 - - - 10.7535 0.9994 221125_WJC_METTL3_EV_vs_WT_F07.19142.19142.3 2.63E-08 14/80 R.YSK[136.11]EEEMDDMDR[166.11]DLGDEYGWK[136.11].Q "sp|Q9HD45|TM9S3_HUMAN,tr|Q5TB53|Q5TB53_HUMAN" 2 2636.0893 2.18 105068 19142 3 2636.100236 879.7037 Transmembrane 9 superfamily member 3 OS=Homo sapiens OX=9606 GN=TM9SF3 PE=1 SV=2 3.97 3124.8 - 209841 - - - 4.1414 - 2.696 0.585 - 225.9 1 2 2 0.0109 21 0 0 0 1.31E+07 6.01E+06 - - - 7.4369 1 221125_WJC_METTL3_EV_vs_WT_F07.19145.19145.4 1.16E-12 26/120 R.YSKEEEMDDMDRDLGDEYGWK.Q "sp|Q9HD45|TM9S3_HUMAN,tr|Q5TB53|Q5TB53_HUMAN" 2 2610.0526 1.52 105069 19145 4 2610.056307 653.5204 Transmembrane 9 superfamily member 3 OS=Homo sapiens OX=9606 GN=TM9SF3 PE=1 SV=2 3.97 3125.2 - 2.44E+06 - - - 1.4015 - 4.158 0.735 - 605.7 1 2 2 0.0037 21 0 0 0 5.00E+07 3.29E+07 - - - 6.0936 1 221125_WJC_METTL3_EV_vs_WT_F07.19146.19146.3 8.74E-13 25/60 K.RGFAFVTFDDHDSVDK.L "sp|Q32P51|RA1L2_HUMAN,sp|P09651|ROA1_HUMAN,tr|A0A7I2YQX9|A0A7I2YQX9_HUMAN,tr|F8VZ49|F8VZ49_HUMAN,tr|A0A7I2V3R8|A0A7I2V3R8_HUMAN,tr|F8VTQ5|F8VTQ5_HUMAN,tr|F8W6I7|F8W6I7_HUMAN,tr|H0YH80|H0YH80_HUMAN,tr|A0A7I2V2L6|A0A7I2V2L6_HUMAN,tr|A0A7I2V3W0|A0A7I2V3W0_HUMAN,tr|A0A7I2V5U9|A0A7I2V5U9_HUMAN,tr|A0A2R8Y4L2|A0A2R8Y4L2_HUMAN" 12 1854.8537 1.07 105070 19146 3 1854.856921 619.2918 Heterogeneous nuclear ribonucleoprotein A1-like 2 OS=Homo sapiens OX=9606 GN=HNRNPA1L2 PE=2 SV=2 4.56 3125.3 - 883928 - - - 1.7489 - 4.284 0.695 - 832.3 1 2 0 0.0032 16 0 0 0 1.39E+07 1.30E+07 - - - 10.0207 1 221125_WJC_METTL3_EV_vs_WT_F07.19147.19147.3 9.81E-13 21/80 K.LKQQEC[160.03]PEC[160.03]DVLSLGTYSASR.S sp|Q10469|MGAT2_HUMAN 1 2440.1363 1.59 105071 19147 3 2440.139426 814.386 "Alpha-1,6-mannosyl-glycoprotein 2-beta-N-acetylglucosaminyltransferase OS=Homo sapiens OX=9606 GN=MGAT2 PE=1 SV=1" 4.68 3125.4 - 1.71E+06 - - - 1.2975 - 3.407 0.663 - 389 1 2 1 0.0032 21 0 0 0 3.29E+07 2.06E+07 - - - 8.8698 1 221125_WJC_METTL3_EV_vs_WT_F07.19148.19148.3 1.08E-10 22/76 R.GGC[160.03]NITAIQDVTGAHIDVDK.Q "sp|Q8IWZ3|ANKH1_HUMAN,tr|A0A0A0MQZ8|A0A0A0MQZ8_HUMAN,tr|H0Y472|H0Y472_HUMAN,tr|H0Y7Y3|H0Y7Y3_HUMAN,tr|H0Y4P6|H0Y4P6_HUMAN,tr|H0Y785|H0Y785_HUMAN" 6 2083.0004 1.56 105072 19148 3 2083.001494 695.3407 Ankyrin repeat and KH domain-containing protein 1 OS=Homo sapiens OX=9606 GN=ANKHD1 PE=1 SV=1 4.41 3125.5 - 1.11E+06 - - - 0.5166 - 4.237 0.617 - 706.6 1 2 0 0.0011 20 0 0 0 2.16E+07 1.39E+07 - - - 8.9215 1 221125_WJC_METTL3_EV_vs_WT_F07.19150.19150.3 2.96E-09 21/96 R.SYGPAPGAGHVQEESNLSLQALESR[166.11].Q sp|Q13155|AIMP2_HUMAN 1 2606.26 0.89 105074 19150 3 2606.260297 869.7606 Aminoacyl tRNA synthase complex-interacting multifunctional protein 2 OS=Homo sapiens OX=9606 GN=AIMP2 PE=1 SV=2 4.75 3125.8 - 653468 - - - 0.1032 - 3.472 0.657 - 319 1 2 0 0.0003 25 0 0 0 1.24E+07 1.40E+07 - - - 8.7285 1 221125_WJC_METTL3_EV_vs_WT_F07.19151.19151.3 6.47E-20 25/68 K.HWDQDDDFEFTGSHLTVR.N "sp|O60341|KDM1A_HUMAN,tr|R4GMQ1|R4GMQ1_HUMAN" 2 2203.9559 1.29 105075 19151 3 2203.960116 735.6592 Lysine-specific histone demethylase 1A OS=Homo sapiens OX=9606 GN=KDM1A PE=1 SV=2 4.34 3125.9 - 636178 - - - 1.9084 - 4.64 0.78 - 1247.3 1 2 0 0.0042 18 0 0 0 1.01E+07 7.84E+06 - - - 11.0567 1 221125_WJC_METTL3_EV_vs_WT_F07.19160.19160.3 5.25E-13 23/96 R.SYGPAPGAGHVQEESNLSLQALESR.Q sp|Q13155|AIMP2_HUMAN 1 2596.2518 0.84 105082 19160 3 2596.25434 866.4245 Aminoacyl tRNA synthase complex-interacting multifunctional protein 2 OS=Homo sapiens OX=9606 GN=AIMP2 PE=1 SV=2 4.75 3127.1 - 970759 - - - 0.9945 - 3.657 0.672 - 532.2 1 2 0 0.0026 25 0 0 0 1.24E+07 1.48E+07 - - - 9.0145 1 221125_WJC_METTL3_EV_vs_WT_F07.19161.19161.3 3.31E-12 28/100 K.RPSTSQTVSTPAPVPVIESTEAIEAK.A sp|P12270|TPR_HUMAN 1 2694.4076 3.79 105083 19161 3 2694.410204 899.1431 Nucleoprotein TPR OS=Homo sapiens OX=9606 GN=TPR PE=1 SV=3 4.79 3127.2 - 758340 - - - 0.9702 - 4.45 0.678 - 776 1 2 0 0.0026 26 0 0 0 2.82E+08 7.44E+07 - - - 9.5329 0.9986 221125_WJC_METTL3_EV_vs_WT_F07.19166.19166.4 5.39E-05 Sep-84 R.GFC[160.03]FITFK[136.11]EEEPVK[136.11]K[136.11].L "sp|Q14103|HNRPD_HUMAN,tr|H0Y8G5|H0Y8G5_HUMAN,tr|H0YA96|H0YA96_HUMAN" 3 1881.9761 1.22 105088 19166 4 1881.978159 471.5013 Heterogeneous nuclear ribonucleoprotein D0 OS=Homo sapiens OX=9606 GN=HNRNPD PE=1 SV=1 6.22 3127.9 - 197886 - - - 1.0898 - 1.808 0.354 - 44.2 1 2 1 0.0021 15 0 0 0 3.43E+07 2.82E+07 - - - 2.5186 1 221125_WJC_METTL3_EV_vs_WT_F07.19172.19172.3 1.01E-10 16/80 R.YSKEEEMDDMDRDLGDEYGWK.Q "sp|Q9HD45|TM9S3_HUMAN,tr|Q5TB53|Q5TB53_HUMAN" 2 2610.0526 2.18 105092 19172 3 2610.046811 871.0248 Transmembrane 9 superfamily member 3 OS=Homo sapiens OX=9606 GN=TM9SF3 PE=1 SV=2 3.97 3128.6 - 821739 - - - -2.2367 - 3.162 0.684 - 207.6 1 2 2 -0.0058 21 0 0 0 1.31E+07 6.01E+06 - - - 8.9243 1 221125_WJC_METTL3_EV_vs_WT_F07.19173.19173.4 5.59E-09 16/120 R.SSADQEEPLPHELR[166.11]PLPVLSR[166.11].T sp|O60318|GANP_HUMAN 1 2389.2505 2.59 105093 19173 4 2389.249184 598.3199 Germinal-center associated nuclear protein OS=Homo sapiens OX=9606 GN=MCM3AP PE=1 SV=2 4.83 3128.7 - 1.22E+06 - - - -0.5353 - 2.677 0.599 - 150.5 1 2 0 -0.0013 21 0 0 0 3.79E+07 1.46E+07 - - - 4.7649 0.9999 221125_WJC_METTL3_EV_vs_WT_F07.19174.19174.4 3.38E-06 15/84 R.GFC[160.03]FITFKEEEPVKK.L "sp|Q14103|HNRPD_HUMAN,tr|H0Y8G5|H0Y8G5_HUMAN,tr|H0YA96|H0YA96_HUMAN" 3 1857.9335 1.22 105094 19174 4 1857.934277 465.4907 Heterogeneous nuclear ribonucleoprotein D0 OS=Homo sapiens OX=9606 GN=HNRNPD PE=1 SV=1 6.22 3128.8 - 446625 - - - 0.4139 - 2.297 0.551 - 139 1 2 1 0.0008 15 0 0 0 3.43E+07 2.82E+07 - - - 4.3192 0.9987 221125_WJC_METTL3_EV_vs_WT_F07.19175.19175.4 0.000413 12/132 R.IVSRPEELREDDVGTGAGLLEIK.K "sp|P49368|TCPG_HUMAN,tr|B4DUR8|B4DUR8_HUMAN" 2 2495.3231 0.18 105095 19175 4 2495.32727 624.8381 T-complex protein 1 subunit gamma OS=Homo sapiens OX=9606 GN=CCT3 PE=1 SV=4 4.36 3129 - 259522 - - - 1.6583 - 2.235 0.369 - 72.1 1 2 1 0.0041 23 0 0 0 9.87E+06 5.63E+07 - - - 2.6972 0.9998 221125_WJC_METTL3_EV_vs_WT_F07.19181.19181.3 2.76E-05 22/80 R.DSFDDRGPSLNPVLDYDHGSR.S "sp|P43243|MATR3_HUMAN,tr|A8MXP9|A8MXP9_HUMAN,tr|D6R991|D6R991_HUMAN,tr|A0A0R4J2E8|A0A0R4J2E8_HUMAN,tr|D6REM6|D6REM6_HUMAN" 5 2361.0622 2.32 105099 19181 3 2361.06782 788.028 Matrin-3 OS=Homo sapiens OX=9606 GN=MATR3 PE=1 SV=2 4.28 3129.7 - 730380 - - - 2.3947 - 3.17 0.56 - 516.5 1 2 1 0.0057 21 0 0 0 2.71E+07 1.17E+07 - - - 7.5479 0.9999 221125_WJC_METTL3_EV_vs_WT_F07.19183.19183.3 9.74E-08 14/80 R.SSADQEEPLPHELRPLPVLSR.T sp|O60318|GANP_HUMAN 1 2369.2339 0.4 105101 19183 3 2369.24307 790.7519 Germinal-center associated nuclear protein OS=Homo sapiens OX=9606 GN=MCM3AP PE=1 SV=2 4.83 3129.9 - 485474 - - - 3.8607 - 3.007 0.56 - 121.9 1 2 0 0.0091 21 0 0 0 7.61E+06 1.91E+07 - - - 7.4204 0.9999 221125_WJC_METTL3_EV_vs_WT_F07.19184.19184.3 5.64E-08 16/76 K.SSQK[136.11]VEVETSGIGDSLLNVK[136.11].C "sp|O75152|ZC11A_HUMAN,tr|E9PQ61|E9PQ61_HUMAN" 2 2105.1187 0.79 105102 19184 3 2105.123732 702.7135 Zinc finger CCCH domain-containing protein 11A OS=Homo sapiens OX=9606 GN=ZC3H11A PE=1 SV=3 4.68 3130.1 - 363214 - - - 2.4003 - 3.051 0.592 - 255.4 1 2 1 0.0051 20 0 0 0 8.94E+06 1.13E+07 - - - 7.845 0.9757 221125_WJC_METTL3_EV_vs_WT_F07.19188.19188.4 0.0198 12/132 K.QSK[136.11]PVTTPEEIAQVATISANGDK[136.11].E "sp|P10809|CH60_HUMAN,tr|A0A7I2V599|A0A7I2V599_HUMAN,tr|E7EXB4|E7EXB4_HUMAN,tr|A0A7I2YQ71|A0A7I2YQ71_HUMAN,tr|E7ESH4|E7ESH4_HUMAN,tr|A0A7I2V5M1|A0A7I2V5M1_HUMAN,tr|A0A7I2V5K3|A0A7I2V5K3_HUMAN,tr|A0A7I2V369|A0A7I2V369_HUMAN" 8 2399.2515 1.38 105104 19188 4 2399.252679 600.8201 "60 kDa heat shock protein, mitochondrial OS=Homo sapiens OX=9606 GN=HSPD1 PE=1 SV=2" 4.68 3130.6 - 633388 - - - 0.4981 - 2.3 0.157 - 90.5 1 2 0 0.0012 23 0 0 0 1.15E+08 8.39E+07 - - - 0.862 1 221125_WJC_METTL3_EV_vs_WT_F07.19189.19189.3 1.10E-12 19/100 K.R[166.11]PSTSQTVSTPAPVPVIESTEAIEAK[136.11].A sp|P12270|TPR_HUMAN 1 2712.4301 3.78 105105 19189 3 2712.425313 905.1506 Nucleoprotein TPR OS=Homo sapiens OX=9606 GN=TPR PE=1 SV=3 4.79 3130.7 - 530048 - - - -1.7501 - 4.185 0.604 - 277.5 1 2 0 -0.0047 26 0 0 0 2.81E+08 7.44E+07 - - - 8.5661 1 221125_WJC_METTL3_EV_vs_WT_F07.19191.19191.3 6.25E-06 18/76 K.NEDEEEEEEEKDEAEDLLGR.G sp|Q9Y5B9|SP16H_HUMAN 1 2405.983 0.37 105107 19191 3 2405.982457 803.0016 FACT complex subunit SPT16 OS=Homo sapiens OX=9606 GN=SUPT16H PE=1 SV=1 3.7 3130.9 - 2.45E+06 - - - -0.239 - 3.294 0.625 - 379.1 1 2 1 -0.0006 20 0 0 0 2.41E+07 6.55E+07 - - - 8.4 1 221125_WJC_METTL3_EV_vs_WT_F07.19197.19197.3 1.25E-10 18/68 K.K[136.11]K[136.11]VEEVLEEEEEEYVVEK[136.11].V "sp|P83916|CBX1_HUMAN,tr|K7ELA4|K7ELA4_HUMAN,tr|J3KS05|J3KS05_HUMAN,tr|B5MD17|B5MD17_HUMAN,tr|C9JWS9|C9JWS9_HUMAN" 5 2260.1424 5.75 105111 19197 3 2260.14821 754.3881 Chromobox protein homolog 1 OS=Homo sapiens OX=9606 GN=CBX1 PE=1 SV=1 4.19 3131.6 - 933252 - - - 2.5529 - 3.631 0.69 - 548.1 1 2 1 0.0058 18 0 0 0 1.37E+08 2.38E+07 - - - 9.4422 1 221125_WJC_METTL3_EV_vs_WT_F07.19198.19198.3 2.55E-06 15/68 K.SSSAEGHTDAVLDLSWNK[136.11].L "sp|Q13610|PWP1_HUMAN,tr|B4DJV5|B4DJV5_HUMAN" 2 1923.9054 1.03 105112 19198 3 1923.904579 642.3091 Periodic tryptophan protein 1 homolog OS=Homo sapiens OX=9606 GN=PWP1 PE=1 SV=1 4.53 3131.8 - 666780 - - - -0.4189 - 2.879 0.548 - 297.1 1 2 0 -0.0008 18 0 0 0 1.15E+07 1.11E+07 - - - 7.2826 1 221125_WJC_METTL3_EV_vs_WT_F07.19199.19199.3 5.53E-11 17/104 R.TDVIQGDDVADATSEVEVSSTSETTPK[136.11].A sp|P49792|RBP2_HUMAN 1 2788.2865 1.2 105113 19199 3 2788.284453 930.4361 E3 SUMO-protein ligase RanBP2 OS=Homo sapiens OX=9606 GN=RANBP2 PE=1 SV=2 3.62 3131.9 - 263438 - - - -0.7478 - 3.418 0.708 - 260 1 2 0 -0.0021 27 0 0 0 3.64E+06 3.02E+06 - - - 9.2605 0.9982 221125_WJC_METTL3_EV_vs_WT_F07.19203.19203.4 0.000354 11/102 K.K[136.11]K[136.11]VEEVLEEEEEEYVVEK[136.11].V "sp|P83916|CBX1_HUMAN,tr|K7ELA4|K7ELA4_HUMAN,tr|J3KS05|J3KS05_HUMAN,tr|B5MD17|B5MD17_HUMAN,tr|C9JWS9|C9JWS9_HUMAN" 5 2260.1424 2.07 105115 19203 4 2260.148071 566.0429 Chromobox protein homolog 1 OS=Homo sapiens OX=9606 GN=CBX1 PE=1 SV=1 4.19 3132.3 - 569527 - - - 2.4914 - 2.123 0.38 - 87.7 1 2 1 0.0056 18 0 0 0 1.91E+07 9.20E+06 - - - 2.7898 0.9999 221125_WJC_METTL3_EV_vs_WT_F07.19205.19205.3 2.51E-08 15/56 R.GFC[160.03]FITFKEEEPVKK.L "sp|Q14103|HNRPD_HUMAN,tr|H0Y8G5|H0Y8G5_HUMAN,tr|H0YA96|H0YA96_HUMAN" 3 1857.9335 0.99 105117 19205 3 1857.936453 620.3184 Heterogeneous nuclear ribonucleoprotein D0 OS=Homo sapiens OX=9606 GN=HNRNPD PE=1 SV=1 6.22 3132.6 - 600396 - - - 1.5851 - 2.981 0.6 - 246.4 1 2 1 0.0029 15 0 0 0 2.08E+07 2.10E+07 - - - 8.0787 1 221125_WJC_METTL3_EV_vs_WT_F07.19206.19206.3 1.44E-10 22/116 K.VDPTYGLESSC[160.03]IAGTGPDEPEKLEGAEEEK.M sp|Q92922|SMRC1_HUMAN 1 3206.4449 11.98 105118 19206 3 3206.44801 1069.8222 SWI\SNF complex subunit SMARCC1 OS=Homo sapiens OX=9606 GN=SMARCC1 PE=1 SV=3 3.89 3132.7 - 384034 - - - 0.9699 - 5.114 0.696 - 447.2 1 2 1 0.0031 30 0 0 0 1.33E+07 1.11E+06 - - - 10.0535 0.9936 221125_WJC_METTL3_EV_vs_WT_F07.19207.19207.3 0.00147 Dec-88 R.IVSR[166.11]PEELR[166.11]EDDVGTGAGLLEIK[136.11].K "sp|P49368|TCPG_HUMAN,tr|B4DUR8|B4DUR8_HUMAN" 2 2523.3539 0.06 105119 19207 3 2523.361844 842.1252 T-complex protein 1 subunit gamma OS=Homo sapiens OX=9606 GN=CCT3 PE=1 SV=4 4.36 3132.8 - 325414 - - - 3.1593 - 2.397 0.321 - 83.9 1 2 1 0.008 23 0 0 0 7.66E+05 1.26E+07 - - - 4.1675 1 221125_WJC_METTL3_EV_vs_WT_F07.19212.19212.4 2.26E-11 18/102 K.KKVEEVLEEEEEEYVVEK.V "sp|P83916|CBX1_HUMAN,tr|K7ELA4|K7ELA4_HUMAN,tr|J3KS05|J3KS05_HUMAN,tr|B5MD17|B5MD17_HUMAN,tr|C9JWS9|C9JWS9_HUMAN" 5 2236.0998 1.2 105122 19212 4 2236.101018 560.0322 Chromobox protein homolog 1 OS=Homo sapiens OX=9606 GN=CBX1 PE=1 SV=1 4.19 3133.5 - 629864 - - - 0.5268 - 3.408 0.667 - 216.9 1 2 1 0.0012 18 0 0 0 1.09E+07 9.16E+06 - - - 5.4513 1 221125_WJC_METTL3_EV_vs_WT_F07.19217.19217.3 3.57E-09 22/76 K.NEDEEEEEEEK[136.11]DEAEDLLGR[166.11].G sp|Q9Y5B9|SP16H_HUMAN 1 2424.0055 0.16 105125 19217 3 2423.99753 809.0091 FACT complex subunit SPT16 OS=Homo sapiens OX=9606 GN=SUPT16H PE=1 SV=1 3.7 3134.1 - 791167 - - - -3.2888 - 4.393 0.653 - 871.6 1 2 1 -0.008 20 0 0 0 2.41E+07 1.54E+08 - - - 9.4086 1 221125_WJC_METTL3_EV_vs_WT_F07.19220.19220.2 3.28E-09 Nov-44 K.QSKPVTTPEEIAQVATISANGDK.E "sp|P10809|CH60_HUMAN,tr|A0A7I2V599|A0A7I2V599_HUMAN,tr|E7EXB4|E7EXB4_HUMAN,tr|A0A7I2YQ71|A0A7I2YQ71_HUMAN,tr|E7ESH4|E7ESH4_HUMAN,tr|A0A7I2V5M1|A0A7I2V5M1_HUMAN,tr|A0A7I2V5K3|A0A7I2V5K3_HUMAN,tr|A0A7I2V369|A0A7I2V369_HUMAN" 8 2383.2231 1.88 105128 19220 2 2383.21905 1192.6188 "60 kDa heat shock protein, mitochondrial OS=Homo sapiens OX=9606 GN=HSPD1 PE=1 SV=2" 4.68 3134.5 - 235342 - - - -1.6927 - 2.356 0.662 - 188 1 2 0 -0.004 23 0 0 0 6.58E+06 3.49E+06 - - - 6.0362 0.9996 221125_WJC_METTL3_EV_vs_WT_F07.19229.19229.4 0.000702 12/138 K.EVMNADDPDLQRPDEEAIKEITEK.T "sp|Q13573|SNW1_HUMAN,tr|G3V3A4|G3V3A4_HUMAN" 2 2784.3124 1.43 105132 19229 4 2784.315111 697.0854 SNW domain-containing protein 1 OS=Homo sapiens OX=9606 GN=SNW1 PE=1 SV=1 4.01 3135.8 - 390556 - - - 0.9848 - 2.042 0.433 - 55.2 1 2 1 0.0027 24 0 0 0 6.94E+07 4.86E+07 - - - 3.2232 0.9997 221125_WJC_METTL3_EV_vs_WT_F07.19231.19231.4 0.000131 10/108 R.GLLQDDAHPTLVTYADHSK[136.11].L "sp|Q86U44|MTA70_HUMAN,tr|F5H6D8|F5H6D8_HUMAN,tr|H0YFV6|H0YFV6_HUMAN,tr|B4DTN4|B4DTN4_HUMAN" 4 2088.0367 0.02 105134 19231 4 2088.038733 523.0165 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 5.13 3136 - 514215 - - - 0.9578 - 2.446 0.352 - 86.3 1 2 0 0.002 19 0 0 0 3.45E+05 1.38E+07 - - - 2.5918 1 221125_WJC_METTL3_EV_vs_WT_F07.19232.19232.3 2.27E-05 Nov-76 R.SNSVGIQDAFNDGSDSTFQK.R "sp|O14497|ARI1A_HUMAN,tr|H0Y488|H0Y488_HUMAN,tr|A0A1B0GTU5|A0A1B0GTU5_HUMAN,tr|A0A087WUV6|A0A087WUV6_HUMAN" 4 2115.9345 1.94 105135 19232 3 2115.936392 706.3188 AT-rich interactive domain-containing protein 1A OS=Homo sapiens OX=9606 GN=ARID1A PE=1 SV=3 3.93 3136.1 - 282264 - - - 0.8913 - 2.249 0.515 - 135.1 1 2 0 0.0019 20 0 0 0 4.76E+06 2.45E+06 - - - 6.2475 0.9994 221125_WJC_METTL3_EV_vs_WT_F07.19236.19236.4 0.0151 14/120 R.EKLQEEMLQREEAENTLQSFR.Q "sp|P08670|VIME_HUMAN,tr|B0YJC4|B0YJC4_HUMAN" 2 2607.2599 1.69 105136 19236 4 2607.259467 652.8222 Vimentin OS=Homo sapiens OX=9606 GN=VIM PE=1 SV=4 4.48 3136.7 - 667351 - - - -0.1584 - 2.275 0.396 - 97 1 2 2 -0.0004 21 0 0 0 2.35E+07 1.39E+07 - - - 2.9444 0.9702 221125_WJC_METTL3_EV_vs_WT_F07.19237.19237.4 0.000579 17/138 K.EVMNADDPDLQR[166.11]PDEEAIK[136.11]EITEK[136.11].T "sp|Q13573|SNW1_HUMAN,tr|G3V3A4|G3V3A4_HUMAN" 2 2810.349 1.43 105137 19237 4 2811.361146 703.5945 SNW domain-containing protein 1 OS=Homo sapiens OX=9606 GN=SNW1 PE=1 SV=1 4.01 3136.9 - 540813 - - - 360.1357 - 3.176 0.47 - 120.7 1 2 1 1.0121 24 0 0 0 6.95E+07 4.86E+07 - - - 3.4074 0.9998 221125_WJC_METTL3_EV_vs_WT_F07.19243.19243.3 9.05E-05 13/56 R.GFC[160.03]FITFK[136.11]EEEPVK[136.11]K[136.11].L "sp|Q14103|HNRPD_HUMAN,tr|H0Y8G5|H0Y8G5_HUMAN,tr|H0YA96|H0YA96_HUMAN" 3 1881.9761 1.49 105141 19243 3 1881.976922 628.3326 Heterogeneous nuclear ribonucleoprotein D0 OS=Homo sapiens OX=9606 GN=HNRNPD PE=1 SV=1 6.22 3137.5 - 281936 - - - 0.4325 - 2.32 0.467 - 184 1 2 1 0.0008 15 0 0 0 1.99E+07 1.33E+07 - - - 5.9423 0.9104 221125_WJC_METTL3_EV_vs_WT_F07.19245.19245.4 0.128 9/102 R.LGSSSLTNIPEEVREHVK.L "sp|Q6P3W7|SCYL2_HUMAN,tr|F8VSC5|F8VSC5_HUMAN,tr|A0A0U1RQQ9|A0A0U1RQQ9_HUMAN" 3 1994.0433 1.85 105143 19245 4 1994.043611 499.5181 SCY1-like protein 2 OS=Homo sapiens OX=9606 GN=SCYL2 PE=1 SV=1 5.5 3137.8 - 429875 - - - 0.1715 - 1.851 0.164 - 39.4 1 2 1 0.0003 18 0 0 0 6.14E+07 3.32E+07 - - - 0.8643 1 221125_WJC_METTL3_EV_vs_WT_F07.19251.19251.2 3.02E-08 Oct-44 K.QSK[136.11]PVTTPEEIAQVATISANGDK[136.11].E "sp|P10809|CH60_HUMAN,tr|A0A7I2V599|A0A7I2V599_HUMAN,tr|E7EXB4|E7EXB4_HUMAN,tr|A0A7I2YQ71|A0A7I2YQ71_HUMAN,tr|E7ESH4|E7ESH4_HUMAN,tr|A0A7I2V5M1|A0A7I2V5M1_HUMAN,tr|A0A7I2V5K3|A0A7I2V5K3_HUMAN,tr|A0A7I2V369|A0A7I2V369_HUMAN" 8 2399.2515 1.51 105147 19251 2 2399.253882 1200.633 "60 kDa heat shock protein, mitochondrial OS=Homo sapiens OX=9606 GN=HSPD1 PE=1 SV=2" 4.68 3138.6 - 218517 - - - 0.9995 - 2.327 0.669 - 168.9 1 2 0 0.0024 23 0 0 0 4.06E+07 2.69E+07 - - - 6.0579 0.9991 221125_WJC_METTL3_EV_vs_WT_F07.19252.19252.4 0.0018 11/132 K.QSKPVTTPEEIAQVATISANGDK.E "sp|P10809|CH60_HUMAN,tr|A0A7I2V599|A0A7I2V599_HUMAN,tr|E7EXB4|E7EXB4_HUMAN,tr|A0A7I2YQ71|A0A7I2YQ71_HUMAN,tr|E7ESH4|E7ESH4_HUMAN,tr|A0A7I2V5M1|A0A7I2V5M1_HUMAN,tr|A0A7I2V5K3|A0A7I2V5K3_HUMAN,tr|A0A7I2V369|A0A7I2V369_HUMAN" 8 2383.2231 1.23 105148 19252 4 2383.225812 596.813 "60 kDa heat shock protein, mitochondrial OS=Homo sapiens OX=9606 GN=HSPD1 PE=1 SV=2" 4.68 3138.7 - 1.36E+06 - - - 1.1447 - 2.041 0.303 - 70.5 1 2 0 0.0027 23 0 0 0 1.15E+08 9.32E+07 - - - 2.0937 0.9999 221125_WJC_METTL3_EV_vs_WT_F07.19261.19261.3 7.25E-10 16/64 R.DRSDC[160.03]LGEHLYVMVNAK.F "sp|P54105|ICLN_HUMAN,tr|E9PJF4|E9PJF4_HUMAN,tr|J3KN38|J3KN38_HUMAN,tr|E9PMI6|E9PMI6_HUMAN" 4 2005.935 2.74 105155 19261 3 2005.93101 669.6523 Methylosome subunit pICln OS=Homo sapiens OX=9606 GN=CLNS1A PE=1 SV=1 5.38 3139.9 - 599902 - - - -1.9796 - 2.867 0.644 - 283.1 1 2 1 -0.004 17 0 0 0 2.78E+07 1.02E+07 - - - 8.3797 0.9999 221125_WJC_METTL3_EV_vs_WT_F07.19262.19262.4 4.50E-06 17/96 K.NQAVC[160.03]HDYDIHFYPTFR[166.11].Y sp|Q6ZRP7|QSOX2_HUMAN 1 2191.9773 1.29 105156 19262 4 2191.972855 549.0016 Sulfhydryl oxidase 2 OS=Homo sapiens OX=9606 GN=QSOX2 PE=1 SV=3 5.98 3140 - 406643 - - - -2.0406 - 2.414 0.481 - 246.7 1 2 0 -0.0045 17 0 0 0 2.04E+07 1.58E+07 - - - 3.7174 0.9998 221125_WJC_METTL3_EV_vs_WT_F07.19263.19263.4 3.47E-08 16/162 K.NITAPSRPPPGLTGQKPPLSTWDNSPLR.L "sp|Q8NDV7|TNR6A_HUMAN,tr|H7C269|H7C269_HUMAN,tr|H3BRT3|H3BRT3_HUMAN" 3 2996.5832 2.23 105157 19263 4 2996.596404 750.1531 Trinucleotide repeat-containing gene 6A protein OS=Homo sapiens OX=9606 GN=TNRC6A PE=1 SV=2 10.84 3140.1 - 847404 - - - 4.405 - 3.083 0.538 - 100.4 1 2 0 0.0132 28 0 0 0 4.56E+07 2.04E+07 - - - 4.2547 1 221125_WJC_METTL3_EV_vs_WT_F07.19265.19265.3 6.03E-06 17/52 R.KVESLQEEIAFLKK.L "sp|P08670|VIME_HUMAN,tr|B0YJC5|B0YJC5_HUMAN,tr|B0YJC4|B0YJC4_HUMAN" 3 1660.94 1.77 105159 19265 3 1660.94292 554.6539 Vimentin OS=Homo sapiens OX=9606 GN=VIM PE=1 SV=4 6.23 3140.4 - 466881 - - - 1.7743 - 3.555 0.558 - 444.5 1 2 0 0.0029 14 0 0 0 1.14E+08 6.46E+07 - - - 8.131 0.9998 221125_WJC_METTL3_EV_vs_WT_F07.19266.19266.4 3.88E-07 13/78 R.YEEIVK[136.11]EVSTYIK[136.11]K[136.11].L "sp|P68104|EF1A1_HUMAN,sp|Q5VTE0|EF1A3_HUMAN,tr|A0A7I2V659|A0A7I2V659_HUMAN,tr|A0A7I2V3H3|A0A7I2V3H3_HUMAN,tr|A0A7I2V5N4|A0A7I2V5N4_HUMAN,tr|A0A087WVQ9|A0A087WVQ9_HUMAN,tr|A0A087WV01|A0A087WV01_HUMAN" 7 1751.9772 0.37 105160 19266 4 1751.977814 439.0016 Elongation factor 1-alpha 1 OS=Homo sapiens OX=9606 GN=EEF1A1 PE=1 SV=1 6.23 3140.5 - 432960 - - - 0.3773 - 2.494 0.487 - 86.8 1 2 1 0.0007 14 0 0 0 4.15E+06 1.11E+07 - - - 3.7973 1 221125_WJC_METTL3_EV_vs_WT_F07.19269.19269.3 7.05E-10 23/88 K.QSK[136.11]PVTTPEEIAQVATISANGDK[136.11].E "sp|P10809|CH60_HUMAN,tr|A0A7I2V599|A0A7I2V599_HUMAN,tr|E7EXB4|E7EXB4_HUMAN,tr|A0A7I2YQ71|A0A7I2YQ71_HUMAN,tr|E7ESH4|E7ESH4_HUMAN,tr|A0A7I2V5M1|A0A7I2V5M1_HUMAN,tr|A0A7I2V5K3|A0A7I2V5K3_HUMAN,tr|A0A7I2V369|A0A7I2V369_HUMAN" 8 2399.2515 1.4 105162 19269 3 2399.251998 800.7578 "60 kDa heat shock protein, mitochondrial OS=Homo sapiens OX=9606 GN=HSPD1 PE=1 SV=2" 4.68 3140.8 - 3.41E+07 - - - 0.2142 - 3.806 0.487 - 535.7 1 2 0 0.0005 23 0 0 0 4.42E+09 3.17E+09 - - - 7.105 1 221125_WJC_METTL3_EV_vs_WT_F07.19275.19275.4 5.96E-05 18/78 R.KVESLQEEIAFLKK.L "sp|P08670|VIME_HUMAN,tr|B0YJC5|B0YJC5_HUMAN,tr|B0YJC4|B0YJC4_HUMAN" 3 1660.94 1.79 105166 19275 4 1660.939928 416.2423 Vimentin OS=Homo sapiens OX=9606 GN=VIM PE=1 SV=4 6.23 3141.5 - 783270 - - - -0.0271 - 3.042 0.484 - 304.2 1 2 0 0 14 0 0 0 6.89E+07 3.85E+07 - - - 3.8436 0.9999 221125_WJC_METTL3_EV_vs_WT_F07.19276.19276.4 9.03E-09 16/78 R.K[136.11]VESLQEEIAFLK[136.11]K[136.11].L "sp|P08670|VIME_HUMAN,tr|B0YJC5|B0YJC5_HUMAN,tr|B0YJC4|B0YJC4_HUMAN" 3 1684.9826 1.79 105167 19276 4 1684.982715 422.2529 Vimentin OS=Homo sapiens OX=9606 GN=VIM PE=1 SV=4 6.23 3141.6 - 582858 - - - 0.0843 - 2.796 0.409 - 232.1 1 2 0 0.0001 14 0 0 0 6.87E+07 3.85E+07 - - - 3.1601 1 221125_WJC_METTL3_EV_vs_WT_F07.19280.19280.4 9.87E-10 19/96 K.NQAVC[160.03]HDYDIHFYPTFR.Y sp|Q6ZRP7|QSOX2_HUMAN 1 2181.9691 1.28 105169 19280 4 2181.96963 546.4995 Sulfhydryl oxidase 2 OS=Homo sapiens OX=9606 GN=QSOX2 PE=1 SV=3 5.98 3142 - 1.37E+06 - - - 0.2621 - 2.715 0.607 - 280.7 1 2 0 0.0006 17 0 0 0 2.04E+07 1.59E+07 - - - 4.8559 0.9987 221125_WJC_METTL3_EV_vs_WT_F07.19293.19293.4 0.0055 Oct-78 R.YEEIVKEVSTYIKK.L "sp|P68104|EF1A1_HUMAN,sp|Q5VTE0|EF1A3_HUMAN,tr|A0A7I2V659|A0A7I2V659_HUMAN,tr|A0A7I2V3H3|A0A7I2V3H3_HUMAN,tr|A0A7I2V5N4|A0A7I2V5N4_HUMAN,tr|A0A087WVQ9|A0A087WVQ9_HUMAN,tr|A0A087WV01|A0A087WV01_HUMAN" 7 1727.9346 0.38 105178 19293 4 1727.934295 432.9909 Elongation factor 1-alpha 1 OS=Homo sapiens OX=9606 GN=EEF1A1 PE=1 SV=1 6.23 3143.7 - 207312 - - - -0.1493 - 1.698 0.362 - 51.8 1 2 1 -0.0003 14 0 0 0 4.15E+06 1.10E+07 - - - 2.5695 1 221125_WJC_METTL3_EV_vs_WT_F07.19296.19296.3 8.99E-10 14/64 K.NQAVC[160.03]HDYDIHFYPTFR.Y sp|Q6ZRP7|QSOX2_HUMAN 1 2181.9691 1.42 105179 19296 3 2181.963982 728.3303 Sulfhydryl oxidase 2 OS=Homo sapiens OX=9606 GN=QSOX2 PE=1 SV=3 5.98 3144.1 - 318281 - - - -2.3263 - 3.03 0.674 - 276.6 1 2 0 -0.0051 17 0 0 0 4.02E+06 2.84E+06 - - - 8.8536 1 221125_WJC_METTL3_EV_vs_WT_F07.19300.19300.3 8.68E-06 13/88 R.K[136.11]TPQGPPEIYSDTQFPSLQSTAK[136.11].H "sp|Q9UKY7|CDV3_HUMAN,tr|D6RFH2|D6RFH2_HUMAN,tr|H0Y8K3|H0Y8K3_HUMAN,tr|D6RDN0|D6RDN0_HUMAN,tr|D6R9V8|D6R9V8_HUMAN" 5 2535.2828 0.57 105182 19300 3 2535.288049 846.1015 Protein CDV3 homolog OS=Homo sapiens OX=9606 GN=CDV3 PE=1 SV=1 6.07 3144.6 - 555177 - - - 2.0767 - 3.073 0.515 - 106.3 1 2 0 0.0053 23 0 0 0 1.03E+07 1.83E+07 - - - 6.914 1 221125_WJC_METTL3_EV_vs_WT_F07.19307.19307.3 7.16E-10 21/100 Y.SSSSGGVGLGGGLSVGGSGFSASSGR.G sp|P13647|K2C5_HUMAN 1 2170.0251 999 105186 19307 3 2170.025558 724.349 "Keratin, type II cytoskeletal 5 OS=Homo sapiens OX=9606 GN=KRT5 PE=1 SV=3" 9.47 3145.6 - 625540 - - - 0.2327 - 3.903 0.636 - 346.8 1 1 0 0.0005 26 0 0 0 2.72E+07 0.00E+00 - - - 8.7635 0.9999 221125_WJC_METTL3_EV_vs_WT_F07.19310.19310.3 0.000197 Nov-44 R.EHALLAYTLGVK[136.11].Q "sp|Q05639|EF1A2_HUMAN,sp|P68104|EF1A1_HUMAN,sp|Q5VTE0|EF1A3_HUMAN,tr|A0A2R8Y488|A0A2R8Y488_HUMAN,tr|A0A7I2V659|A0A7I2V659_HUMAN,tr|A0A7I2V3H3|A0A7I2V3H3_HUMAN,tr|A0A2U3TZH3|A0A2U3TZH3_HUMAN,tr|A0A7I2V5N4|A0A7I2V5N4_HUMAN,tr|A0A087WVQ9|A0A087WVQ9_HUMAN,tr|A0A087WV01|A0A087WV01_HUMAN,tr|A0A2R8Y660|A0A2R8Y660_HUMAN" 11 1321.7485 1.65 105187 19310 3 1321.749895 441.5901 Elongation factor 1-alpha 2 OS=Homo sapiens OX=9606 GN=EEF1A2 PE=1 SV=1 6.85 3145.9 - 324168 - - - 1.0274 - 2.471 0.411 - 193.7 1 2 0 0.0014 12 0 0 0 1.06E+07 6.42E+06 - - - 5.6293 0.9999 221125_WJC_METTL3_EV_vs_WT_F07.19312.19312.4 0.000143 15/162 K.NITAPSR[166.11]PPPGLTGQK[136.11]PPLSTWDNSPLR[166.11].L "sp|Q8NDV7|TNR6A_HUMAN,tr|H7C269|H7C269_HUMAN,tr|H3BRT3|H3BRT3_HUMAN" 3 3024.6139 2.23 105188 19312 4 3024.619442 757.1608 Trinucleotide repeat-containing gene 6A protein OS=Homo sapiens OX=9606 GN=TNRC6A PE=1 SV=2 10.84 3146.2 - 628190 - - - 1.8178 - 2.837 0.454 - 56 1 2 0 0.0055 28 0 0 0 4.56E+07 2.04E+07 - - - 3.4998 1 221125_WJC_METTL3_EV_vs_WT_F07.19313.19313.3 1.03E-05 14/92 R.ISGVALHDQGQYEC[160.03]QAVNIIGSQK[136.11].V "sp|Q92626|PXDN_HUMAN,tr|H7C1W1|H7C1W1_HUMAN" 2 2622.2951 1.78 105189 19313 3 2622.296199 875.1057 Peroxidasin homolog OS=Homo sapiens OX=9606 GN=PXDN PE=1 SV=2 5.32 3146.3 - 327102 - - - 0.4 - 2.347 0.521 - 25.4 1 2 0 0.001 24 0 0 0 1.63E+07 9.16E+06 - - - 6.3298 1 221125_WJC_METTL3_EV_vs_WT_F07.19324.19324.2 5.59E-12 17/50 Y.SSSSGGVGLGGGLSVGGSGFSASSGR.G sp|P13647|K2C5_HUMAN 1 2170.0251 999 105194 19324 2 2170.026741 1086.0198 "Keratin, type II cytoskeletal 5 OS=Homo sapiens OX=9606 GN=KRT5 PE=1 SV=3" 9.47 3147.8 - 345810 - - - 0.7779 - 3.344 0.644 - 570.5 1 1 0 0.0017 26 0 0 0 4.57E+06 0.00E+00 - - - 6.7649 1 221125_WJC_METTL3_EV_vs_WT_F07.19328.19328.3 1.09E-10 20/100 K.QPAIMPGQSYGLEDGSC[160.03]SYK[136.11]DFSESR[166.11].N "sp|P14866|HNRPL_HUMAN,tr|M0QYT0|M0QYT0_HUMAN,tr|A0A3B3ITJ4|A0A3B3ITJ4_HUMAN,tr|M0QXS5|M0QXS5_HUMAN" 4 2926.2868 1.22 105196 19328 3 2926.286316 976.4362 Heterogeneous nuclear ribonucleoprotein L OS=Homo sapiens OX=9606 GN=HNRNPL PE=1 SV=2 4.32 3148.4 - 389130 - - - -0.1801 - 3.304 0.713 - 246.4 1 2 1 -0.0005 26 0 0 0 9.68E+07 7.96E+07 - - - 9.2387 1 221125_WJC_METTL3_EV_vs_WT_F07.19331.19331.3 2.54E-11 16/92 R.ISGVALHDQGQYEC[160.03]QAVNIIGSQK.V "sp|Q92626|PXDN_HUMAN,tr|H7C1W1|H7C1W1_HUMAN" 2 2614.2809 1.72 105199 19331 3 2614.282134 872.4343 Peroxidasin homolog OS=Homo sapiens OX=9606 GN=PXDN PE=1 SV=2 5.32 3148.8 - 652089 - - - 0.4529 - 3.718 0.694 - 261.8 1 2 0 0.0012 24 0 0 0 1.63E+07 9.48E+06 - - - 9.3271 0.9999 221125_WJC_METTL3_EV_vs_WT_F07.19335.19335.4 7.46E-05 16/144 R.SRPPEERPPGLPLPPPPPSSSAVFR.L sp|P48634|PRC2A_HUMAN 1 2663.4184 3.44 105202 19335 4 2663.42034 666.8619 Protein PRRC2A OS=Homo sapiens OX=9606 GN=PRRC2A PE=1 SV=3 9.23 3149.2 - 570747 - - - 0.7397 - 2.561 0.411 - 100.4 1 2 0 0.002 25 0 0 0 3.03E+07 8.82E+06 - - - 3.102 1 221125_WJC_METTL3_EV_vs_WT_F07.19337.19337.4 2.29E-10 27/168 R.VAELLLLHGAEPNC[160.03]ADPATLTRPVHDAAR.E "sp|P42771|CDN2A_HUMAN,sp|P42772|CDN2B_HUMAN,tr|K7ENC6|K7ENC6_HUMAN,tr|J3QRG6|J3QRG6_HUMAN,tr|K7ES20|K7ES20_HUMAN" 5 3106.5982 2.3 105203 19337 4 3106.603374 777.6568 Cyclin-dependent kinase inhibitor 2A OS=Homo sapiens OX=9606 GN=CDKN2A PE=1 SV=2 5.31 3149.4 - 1.91E+06 - - - 1.6648 - 4.631 0.625 - 187 1 2 0 0.0052 29 0 0 0 1.49E+08 6.49E+07 - - - 5.137 1 221125_WJC_METTL3_EV_vs_WT_F07.19338.19338.4 5.22E-10 27/168 R.VAELLLLHGAEPNC[160.03]ADPATLTR[166.11]PVHDAAR[166.11].E "sp|P42771|CDN2A_HUMAN,sp|P42772|CDN2B_HUMAN,tr|K7ENC6|K7ENC6_HUMAN,tr|J3QRG6|J3QRG6_HUMAN,tr|K7ES20|K7ES20_HUMAN" 5 3126.6147 2.3 105204 19338 4 3126.6146 782.661 Cyclin-dependent kinase inhibitor 2A OS=Homo sapiens OX=9606 GN=CDKN2A PE=1 SV=2 5.31 3149.6 - 793631 - - - -0.0454 - 3.252 0.577 - 228.9 1 2 0 -0.0001 29 0 0 0 1.49E+08 6.49E+07 - - - 4.6116 1 221125_WJC_METTL3_EV_vs_WT_F07.19342.19342.3 1.53E-10 27/100 K.QPAIMPGQSYGLEDGSC[160.03]SYKDFSESR.N "sp|P14866|HNRPL_HUMAN,tr|M0QYT0|M0QYT0_HUMAN,tr|A0A3B3ITJ4|A0A3B3ITJ4_HUMAN,tr|M0QXS5|M0QXS5_HUMAN" 4 2908.2644 1.22 105206 19342 3 2908.266158 970.4287 Heterogeneous nuclear ribonucleoprotein L OS=Homo sapiens OX=9606 GN=HNRNPL PE=1 SV=2 4.32 3150.1 - 934092 - - - 0.6138 - 4.057 0.723 - 530.4 1 2 1 0.0018 26 0 0 0 9.68E+07 7.96E+07 - - - 9.8222 0.9979 221125_WJC_METTL3_EV_vs_WT_F07.19343.19343.4 0.0559 14/162 R.TGTELVLLTAAPPPPPRPGPC[160.03]AYAAHGR.G "sp|Q96B36|AKTS1_HUMAN,tr|H9KV91|H9KV91_HUMAN" 2 2866.4912 2.26 105207 19343 4 2866.494945 717.6301 Proline-rich AKT1 substrate 1 OS=Homo sapiens OX=9606 GN=AKT1S1 PE=1 SV=1 7.92 3150.2 - 348749 - - - 1.3002 - 2.098 0.266 - 108.7 1 2 0 0.0037 28 0 0 0 1.71E+07 7.59E+06 - - - 1.7703 1 221125_WJC_METTL3_EV_vs_WT_F07.19344.19344.3 1.64E-07 16/108 K.LVSLSEQNLVDC[160.03]SRPQGNQGC[160.03]NGGFMAR.A "sp|O60911|CATL2_HUMAN,tr|A0A7P0T983|A0A7P0T983_HUMAN,tr|A0A7P0Z415|A0A7P0Z415_HUMAN,tr|A0A804EQJ3|A0A804EQJ3_HUMAN" 4 3093.4179 999 105208 19344 3 3093.417484 1032.1466 Cathepsin L2 OS=Homo sapiens OX=9606 GN=CTSV PE=1 SV=2 6.06 3150.4 - 335805 - - - -0.1251 - 3.118 0.591 - 195.2 1 2 0 -0.0004 28 0 0 0 6.59E+06 0.00E+00 - - - 7.7452 1 221125_WJC_METTL3_EV_vs_WT_F07.19350.19350.3 2.97E-08 15/72 K.QQQTVFIHPNSSLFEQQPR.W "sp|O60231|DHX16_HUMAN,tr|Q5SQH5|Q5SQH5_HUMAN,tr|A0A140T8Y5|A0A140T8Y5_HUMAN" 3 2283.1396 2.7 105212 19350 3 2283.143735 762.0538 Pre-mRNA-splicing factor ATP-dependent RNA helicase DHX16 OS=Homo sapiens OX=9606 GN=DHX16 PE=1 SV=2 6.75 3151.1 - 475219 - - - 1.7984 - 3.202 0.482 - 216.8 1 2 0 0.0041 19 0 0 0 1.64E+07 6.06E+06 - - - 6.7719 0.9998 221125_WJC_METTL3_EV_vs_WT_F07.19351.19351.3 0.000291 Nov-48 R.SIFDHIKLPQASK.S "sp|Q9NYF8|BCLF1_HUMAN,tr|E9PKI6|E9PKI6_HUMAN,tr|A0A1W2PQ43|A0A1W2PQ43_HUMAN,tr|E9PK91|E9PK91_HUMAN,tr|E9PJA7|E9PJA7_HUMAN,tr|E9PK09|E9PK09_HUMAN,tr|E9PQN2|E9PQN2_HUMAN" 7 1482.8195 2.14 105213 19351 3 1482.819846 495.2804 Bcl-2-associated transcription factor 1 OS=Homo sapiens OX=9606 GN=BCLAF1 PE=1 SV=2 8.33 3151.2 - 267753 - - - 0.2576 - 2.098 0.52 - 100.1 1 2 1 0.0004 13 0 0 0 1.08E+08 5.02E+07 - - - 6.3464 1 221125_WJC_METTL3_EV_vs_WT_F07.19354.19354.3 8.65E-05 26/108 K.IQIASESSGIPERPC[160.03]VLTGTPESIEQAK.R sp|Q96I24|FUBP3_HUMAN 1 2996.5125 2.06 105214 19354 3 2996.51104 999.8448 Far upstream element-binding protein 3 OS=Homo sapiens OX=9606 GN=FUBP3 PE=1 SV=2 4.49 3151.6 - 1.16E+06 - - - -0.4759 - 4.31 0.613 - 432.1 1 2 0 -0.0014 28 0 0 0 1.97E+08 9.58E+07 - - - 8.735 0.9997 221125_WJC_METTL3_EV_vs_WT_F07.19359.19359.3 0.000177 Sep-40 K.LKVPEWVDTVK.L "sp|P39019|RS19_HUMAN,tr|M0R140|M0R140_HUMAN,tr|M0R2L9|M0R2L9_HUMAN,tr|M0QYF7|M0QYF7_HUMAN" 4 1312.7391 1.12 105218 19359 3 1312.739304 438.587 40S ribosomal protein S19 OS=Homo sapiens OX=9606 GN=RPS19 PE=1 SV=2 6.07 3152.2 - 346001 - - - 0.1645 - 2.036 0.444 - 136.6 1 2 1 0.0002 11 0 0 0 1.48E+07 1.33E+07 - - - 5.5099 1 221125_WJC_METTL3_EV_vs_WT_F07.19362.19362.3 7.48E-12 23/108 K.IQIASESSGIPER[166.11]PC[160.03]VLTGTPESIEQAK[136.11].R sp|Q96I24|FUBP3_HUMAN 1 3014.5349 2.06 105219 19362 3 3014.532367 1005.8523 Far upstream element-binding protein 3 OS=Homo sapiens OX=9606 GN=FUBP3 PE=1 SV=2 4.49 3152.6 - 1.20E+06 - - - -0.8522 - 3.955 0.614 - 321.5 1 2 0 -0.0026 28 0 0 0 1.97E+08 9.58E+07 - - - 8.5481 1 221125_WJC_METTL3_EV_vs_WT_F07.19363.19363.4 5.56E-09 30/114 R.QHVVYGPWNLPQSSYSHLTR.Q sp|Q16610|ECM1_HUMAN 1 2368.1713 170.85 105220 19363 4 2368.174098 593.0501 Extracellular matrix protein 1 OS=Homo sapiens OX=9606 GN=ECM1 PE=1 SV=2 8.6 3152.7 - 1.24E+06 - - - 1.1971 - 4.685 0.568 - 768.8 1 2 0 0.0028 20 0 0 0 2.71E+07 1.58E+05 - - - 4.6854 0.9848 221125_WJC_METTL3_EV_vs_WT_F07.19364.19364.4 0.00702 10/108 K.EAEK[136.11]PAVPETAGIK[136.11]FPDFK[136.11].S sp|Q9NPF5|DMAP1_HUMAN 1 2097.1209 1.37 105221 19364 4 2097.121558 525.2875 DNA methyltransferase 1-associated protein 1 OS=Homo sapiens OX=9606 GN=DMAP1 PE=1 SV=1 4.87 3152.9 - 354895 - - - 0.3343 - 2.161 0.233 - 59.9 1 2 1 0.0007 19 0 0 0 1.01E+08 7.42E+07 - - - 1.5145 1 221125_WJC_METTL3_EV_vs_WT_F07.19373.19373.3 4.81E-10 22/88 K.QSKPVTTPEEIAQVATISANGDK.E "sp|P10809|CH60_HUMAN,tr|A0A7I2V599|A0A7I2V599_HUMAN,tr|E7EXB4|E7EXB4_HUMAN,tr|A0A7I2YQ71|A0A7I2YQ71_HUMAN,tr|E7ESH4|E7ESH4_HUMAN,tr|A0A7I2V5M1|A0A7I2V5M1_HUMAN,tr|A0A7I2V5K3|A0A7I2V5K3_HUMAN,tr|A0A7I2V369|A0A7I2V369_HUMAN" 8 2383.2231 1.39 105226 19373 3 2383.225125 795.415 "60 kDa heat shock protein, mitochondrial OS=Homo sapiens OX=9606 GN=HSPD1 PE=1 SV=2" 4.68 3154 - 4.25E+07 - - - 0.8564 - 4.042 0.598 - 524.4 1 2 0 0.002 23 0 0 0 4.44E+09 3.19E+09 - - - 8.4832 0.9989 221125_WJC_METTL3_EV_vs_WT_F07.19375.19375.4 6.83E-05 17/162 K.IQIASESSGIPER[166.11]PC[160.03]VLTGTPESIEQAK[136.11].R sp|Q96I24|FUBP3_HUMAN 1 3014.5349 1.36 105228 19375 4 3014.522191 754.641 Far upstream element-binding protein 3 OS=Homo sapiens OX=9606 GN=FUBP3 PE=1 SV=2 4.49 3154.3 - 724370 - - - -4.2278 - 3.456 0.387 - 133.2 1 2 0 -0.0127 28 0 0 0 9.66E+07 7.11E+07 - - - 2.9759 1 221125_WJC_METTL3_EV_vs_WT_F07.19380.19380.4 2.46E-06 19/162 K.IQIASESSGIPERPC[160.03]VLTGTPESIEQAK.R sp|Q96I24|FUBP3_HUMAN 1 2996.5125 1.58 105231 19380 4 2996.508616 750.1354 Far upstream element-binding protein 3 OS=Homo sapiens OX=9606 GN=FUBP3 PE=1 SV=2 4.49 3155 - 2.22E+06 - - - -1.2848 - 3.418 0.486 - 176.3 1 2 0 -0.0039 28 0 0 0 5.89E+07 3.73E+07 - - - 3.8367 0.9999 221125_WJC_METTL3_EV_vs_WT_F07.19381.19381.4 8.91E-07 17/150 K.QPAIMPGQSYGLEDGSC[160.03]SYK[136.11]DFSESR[166.11].N "sp|P14866|HNRPL_HUMAN,tr|M0QYT0|M0QYT0_HUMAN,tr|A0A3B3ITJ4|A0A3B3ITJ4_HUMAN,tr|M0QXS5|M0QXS5_HUMAN" 4 2926.2868 1.17 105232 19381 4 2926.292474 732.579 Heterogeneous nuclear ribonucleoprotein L OS=Homo sapiens OX=9606 GN=HNRNPL PE=1 SV=2 4.32 3155.1 - 368820 - - - 1.9243 - 3.564 0.572 - 158.6 1 2 1 0.0056 26 0 0 0 5.01E+06 4.30E+06 - - - 4.604 0.9999 221125_WJC_METTL3_EV_vs_WT_F07.19384.19384.4 5.75E-07 15/102 K.NVQDAIADAEQRGEHALK.D sp|P35908|K22E_HUMAN 1 1963.9712 7197.37 105233 19384 4 1963.972934 492.0001 "Keratin, type II cytoskeletal 2 epidermal OS=Homo sapiens OX=9606 GN=KRT2 PE=1 SV=2" 4.75 3155.5 - 2.03E+06 - - - 0.8997 - 2.775 0.506 - 170.2 1 2 1 0.0018 18 0 0 0 1.54E+09 2.14E+05 - - - 3.9794 0.9768 221125_WJC_METTL3_EV_vs_WT_F07.19386.19386.4 4.53E-10 22/114 Q.EQHVQIDVDVSKPDLTAALR.D "sp|P08670|VIME_HUMAN,tr|B0YJC5|B0YJC5_HUMAN,tr|B0YJC4|B0YJC4_HUMAN" 3 2233.1703 2.64 105235 19386 4 2233.181038 559.2998 Vimentin OS=Homo sapiens OX=9606 GN=VIM PE=1 SV=4 4.66 3155.7 - 533737 - - - 4.8263 - 3.512 0.574 - 321 1 1 0 0.0108 20 0 0 0 1.22E+07 4.62E+06 - - - 4.6391 0.9999 221125_WJC_METTL3_EV_vs_WT_F07.19389.19389.3 1.45E-08 18/68 K.NVQDAIADAEQRGEHALK.D sp|P35908|K22E_HUMAN 1 1963.9712 3978.13 105236 19389 3 1963.973419 655.6643 "Keratin, type II cytoskeletal 2 epidermal OS=Homo sapiens OX=9606 GN=KRT2 PE=1 SV=2" 4.75 3156.1 - 1.59E+06 - - - 1.1467 - 3.555 0.575 - 267.5 1 2 1 0.0023 18 0 0 0 8.32E+08 2.09E+05 - - - 8.1084 0.9988 221125_WJC_METTL3_EV_vs_WT_F07.19391.19391.4 0.00179 17/108 K.EAEKPAVPETAGIKFPDFK.S sp|Q9NPF5|DMAP1_HUMAN 1 2073.0783 1.34 105238 19391 4 2073.082569 519.2768 DNA methyltransferase 1-associated protein 1 OS=Homo sapiens OX=9606 GN=DMAP1 PE=1 SV=1 4.87 3156.4 - 1.66E+06 - - - 2.08 - 3.013 0.377 - 140.1 1 2 1 0.0043 19 0 0 0 1.02E+08 7.57E+07 - - - 2.8793 0.9998 221125_WJC_METTL3_EV_vs_WT_F07.19392.19392.3 0.0236 7/116 K.YTELPHGAISEDQAVGPADIPC[160.03]DSTGQTST.- "sp|Q9H773|DCTP1_HUMAN,tr|H3BPN2|H3BPN2_HUMAN,tr|H3BSA6|H3BSA6_HUMAN" 3 3116.3881 - 105239 19392 3 3116.39071 1039.8033 dCTP pyrophosphatase 1 OS=Homo sapiens OX=9606 GN=DCTPP1 PE=1 SV=1 3.77 3156.5 - 280654 - - - 0.8523 - 1.669 0.421 - 30.1 1 2 0 0.0027 30 0 0 0 - - - - - 4.4114 1 221125_WJC_METTL3_EV_vs_WT_F07.19396.19396.3 1.03E-10 23/96 R.VGETFHASQPSLTVDGFTDPSNSER.F "sp|Q15796|SMAD2_HUMAN,tr|B7Z5N5|B7Z5N5_HUMAN" 2 2677.2256 0.94 105242 19396 3 2677.226667 893.4158 Mothers against decapentaplegic homolog 2 OS=Homo sapiens OX=9606 GN=SMAD2 PE=1 SV=1 4.31 3157 - 1.63E+06 - - - 0.3974 - 3.812 0.651 - 268.6 1 2 0 0.0011 25 0 0 0 5.46E+07 5.79E+07 - - - 8.8763 0.9999 221125_WJC_METTL3_EV_vs_WT_F07.19399.19399.3 2.13E-06 16/72 K.EAEKPAVPETAGIKFPDFK.S sp|Q9NPF5|DMAP1_HUMAN 1 2073.0783 1.41 105244 19399 3 2073.081112 692.0334 DNA methyltransferase 1-associated protein 1 OS=Homo sapiens OX=9606 GN=DMAP1 PE=1 SV=1 4.87 3157.3 - 573111 - - - 1.3772 - 3.008 0.518 - 238.5 1 2 1 0.0029 19 0 0 0 2.79E+07 1.98E+07 - - - 7.02 1 221125_WJC_METTL3_EV_vs_WT_F07.19408.19408.3 8.61E-10 23/68 R.NLNHSLPSDFTFQNMNSK.R sp|Q15208|STK38_HUMAN 1 2092.9636 3.42 105251 19408 3 2092.965636 698.6618 Serine\threonine-protein kinase 38 OS=Homo sapiens OX=9606 GN=STK38 PE=1 SV=1 6.74 3158.3 - 2.63E+06 - - - 0.9546 - 3.554 0.617 - 912.4 1 2 0 0.002 18 0 0 0 9.41E+07 2.75E+07 - - - 8.576 0.9999 221125_WJC_METTL3_EV_vs_WT_F07.19410.19410.4 4.12E-08 17/108 R.DK[136.11]VAGHSLGYGFVNYVTAK[136.11].D "sp|Q15717|ELAV1_HUMAN,tr|M0QZR9|M0QZR9_HUMAN" 2 2041.0604 1.33 105253 19410 4 2041.060164 511.2724 ELAV-like protein 1 OS=Homo sapiens OX=9606 GN=ELAVL1 PE=1 SV=2 8.44 3158.5 - 1.09E+06 - - - -0.1039 - 3.249 0.514 - 197.6 1 2 1 -0.0002 19 0 0 0 4.94E+07 3.72E+07 - - - 4.0984 1 221125_WJC_METTL3_EV_vs_WT_F07.19411.19411.3 3.52E-06 19/68 R.NLNHSLPSDFTFQNMNSK[136.11].R sp|Q15208|STK38_HUMAN 1 2100.9778 3.42 105254 19411 3 2100.979929 701.3332 Serine\threonine-protein kinase 38 OS=Homo sapiens OX=9606 GN=STK38 PE=1 SV=1 6.74 3158.7 - 979257 - - - 0.9953 - 3.68 0.543 - 454.1 1 2 0 0.0021 18 0 0 0 9.41E+07 2.75E+07 - - - 7.8377 0.9998 221125_WJC_METTL3_EV_vs_WT_F07.19414.19414.2 3.45E-07 14/22 K.LNDLEDALQQAK.E sp|P04264|K2C1_HUMAN 1 1356.6885 999 105255 19414 2 1356.689828 679.3515 "Keratin, type II cytoskeletal 1 OS=Homo sapiens OX=9606 GN=KRT1 PE=1 SV=6" 4.03 3159.1 - 1.36E+06 - - - 0.9722 - 3.005 0.39 - 885.5 1 2 0 0.0013 12 0 0 0 3.61E+07 0.00E+00 - - - 4.8161 1 221125_WJC_METTL3_EV_vs_WT_F07.19415.19415.3 2.17E-11 22/72 R.DK[136.11]VAGHSLGYGFVNYVTAK[136.11].D "sp|Q15717|ELAV1_HUMAN,tr|M0QZR9|M0QZR9_HUMAN" 2 2041.0604 1.38 105256 19415 3 2041.059335 681.3607 ELAV-like protein 1 OS=Homo sapiens OX=9606 GN=ELAVL1 PE=1 SV=2 8.44 3159.2 - 1.20E+06 - - - -0.51 - 4.045 0.557 - 753.5 1 2 1 -0.001 19 0 0 0 4.09E+07 2.97E+07 - - - 8.183 1 221125_WJC_METTL3_EV_vs_WT_F07.19416.19416.3 1.33E-08 16/64 K.TSDANETEDHLESLIC[160.03]K[136.11].V "sp|Q09161|NCBP1_HUMAN,tr|F2Z2T1|F2Z2T1_HUMAN" 2 1968.8826 1.13 105257 19416 3 1968.880596 657.3015 Nuclear cap-binding protein subunit 1 OS=Homo sapiens OX=9606 GN=NCBP1 PE=1 SV=1 4.17 3159.2 - 2.65E+06 - - - -1.0183 - 3.643 0.604 - 274.6 1 2 0 -0.002 17 0 0 0 7.69E+07 6.78E+07 - - - 8.5395 0.9998 221125_WJC_METTL3_EV_vs_WT_F07.19419.19419.3 2.24E-06 13/48 R.SIFDHIK[136.11]LPQASK[136.11].S "sp|Q9NYF8|BCLF1_HUMAN,tr|E9PKI6|E9PKI6_HUMAN,tr|A0A1W2PQ43|A0A1W2PQ43_HUMAN,tr|E9PK91|E9PK91_HUMAN,tr|E9PJA7|E9PJA7_HUMAN,tr|E9PK09|E9PK09_HUMAN,tr|E9PQN2|E9PQN2_HUMAN" 7 1498.8479 2.14 105260 19419 3 1498.850838 500.6232 Bcl-2-associated transcription factor 1 OS=Homo sapiens OX=9606 GN=BCLAF1 PE=1 SV=2 8.33 3159.6 - 403176 - - - 1.9842 - 2.43 0.519 - 134 1 2 1 0.003 13 0 0 0 1.08E+08 5.03E+07 - - - 6.7328 0.9639 221125_WJC_METTL3_EV_vs_WT_F07.19420.19420.3 4.79E-05 16/60 V.QDAIADAEQRGEHALK.D sp|P35908|K22E_HUMAN 1 1750.8598 999 105261 19420 3 1750.864098 584.6272 "Keratin, type II cytoskeletal 2 epidermal OS=Homo sapiens OX=9606 GN=KRT2 PE=1 SV=2" 4.75 3159.7 - 222043 - - - 2.4405 - 2.954 0.466 - 342.9 1 1 1 0.0043 16 0 0 0 2.29E+07 0.00E+00 - - - 6.5135 0.9999 221125_WJC_METTL3_EV_vs_WT_F07.19423.19423.4 4.99E-08 16/108 R.DKVAGHSLGYGFVNYVTAK.D "sp|Q15717|ELAV1_HUMAN,tr|M0QZR9|M0QZR9_HUMAN" 2 2025.032 1.33 105262 19423 4 2025.03281 507.2653 ELAV-like protein 1 OS=Homo sapiens OX=9606 GN=ELAVL1 PE=1 SV=2 8.44 3160.1 - 2.55E+06 - - - 0.4118 - 3.572 0.571 - 208.7 1 2 1 0.0008 19 0 0 0 5.01E+07 3.76E+07 - - - 4.6264 1 221125_WJC_METTL3_EV_vs_WT_F07.19424.19424.3 1.23E-07 22/52 K.HTTSIFDDFSHYEK[136.11].R sp|Q9Y5A9|YTHD2_HUMAN 1 1733.7777 1.37 105263 19424 3 1733.775648 578.9332 YTH domain-containing family protein 2 OS=Homo sapiens OX=9606 GN=YTHDF2 PE=1 SV=2 5.21 3160.3 - 999456 - - - -1.1634 - 3.668 0.631 - 488.4 1 2 0 -0.002 14 0 0 0 2.68E+09 1.95E+09 - - - 9.0283 1 221125_WJC_METTL3_EV_vs_WT_F07.19425.19425.3 8.06E-12 23/52 K.HTTSIFDDFSHYEK.R sp|Q9Y5A9|YTHD2_HUMAN 1 1725.7635 1.38 105264 19425 3 1725.767038 576.2618 YTH domain-containing family protein 2 OS=Homo sapiens OX=9606 GN=YTHDF2 PE=1 SV=2 5.21 3160.4 - 1.06E+06 - - - 2.0704 - 3.911 0.677 - 535.8 1 2 0 0.0036 14 0 0 0 2.69E+09 1.95E+09 - - - 9.7112 1 221125_WJC_METTL3_EV_vs_WT_F07.19426.19426.4 1.07E-11 31/156 K.VVETDPSPYC[160.03]IVAPDTVIHC[160.03]EGEPIKR.E "sp|P55072|TERA_HUMAN,tr|A0A7P0Z4C6|A0A7P0Z4C6_HUMAN,tr|A0A7P0T8Q4|A0A7P0T8Q4_HUMAN,tr|A0A7I2V2Y2|A0A7I2V2Y2_HUMAN,tr|A0A7P0T8D6|A0A7P0T8D6_HUMAN,tr|A0A7P0T8Q5|A0A7P0T8Q5_HUMAN,tr|C9JUP7|C9JUP7_HUMAN,tr|A0A7P0TAW3|A0A7P0TAW3_HUMAN,tr|A0A7I2V540|A0A7I2V540_HUMAN,tr|A0A7P0T8A3|A0A7P0T8A3_HUMAN,tr|A0A7P0TAQ1|A0A7P0TAQ1_HUMAN,tr|A0A7I2V5G8|A0A7I2V5G8_HUMAN,tr|A0A7P0T9X5|A0A7P0T9X5_HUMAN" 13 3080.4947 1.63 105265 19426 4 3080.492376 771.131 Transitional endoplasmic reticulum ATPase OS=Homo sapiens OX=9606 GN=VCP PE=1 SV=4 4.5 3160.5 - 580550 - - - -0.757 - 5.239 0.628 - 592.1 1 2 0 -0.0023 27 0 0 0 1.10E+07 6.73E+06 - - - 5.2097 1 221125_WJC_METTL3_EV_vs_WT_F07.19427.19427.4 5.38E-10 19/78 K.HTTSIFDDFSHYEK.R sp|Q9Y5A9|YTHD2_HUMAN 1 1725.7635 1.39 105266 19427 4 1725.763152 432.4481 YTH domain-containing family protein 2 OS=Homo sapiens OX=9606 GN=YTHDF2 PE=1 SV=2 5.21 3160.6 - 293101 - - - -0.1814 - 3.289 0.673 - 212.9 1 2 0 -0.0003 14 0 0 0 8.09E+08 5.83E+08 - - - 5.517 0.9998 221125_WJC_METTL3_EV_vs_WT_F07.19430.19430.4 5.61E-05 22/126 K.HFSIHPDTGVITTTTPFLDREK.C sp|Q08554|DSC1_HUMAN 1 2511.2758 2.56 105267 19430 4 2511.276853 628.8262 Desmocollin-1 OS=Homo sapiens OX=9606 GN=DSC1 PE=1 SV=2 6 3161 - 781278 - - - 0.4241 - 3.788 0.477 - 339 1 2 1 0.0011 22 0 0 0 1.11E+07 4.34E+06 - - - 3.8133 1 221125_WJC_METTL3_EV_vs_WT_F07.19433.19433.4 7.21E-07 18/78 K.HTTSIFDDFSHYEK[136.11].R sp|Q9Y5A9|YTHD2_HUMAN 1 1733.7777 1.39 105270 19433 4 1733.775668 434.4517 YTH domain-containing family protein 2 OS=Homo sapiens OX=9606 GN=YTHDF2 PE=1 SV=2 5.21 3161.4 - 863345 - - - -1.1518 - 3.313 0.565 - 172.2 1 2 0 -0.002 14 0 0 0 8.07E+08 5.82E+08 - - - 4.5792 0.9995 221125_WJC_METTL3_EV_vs_WT_F07.19448.19448.4 1.41E-05 22/114 R.VK[136.11]EEDESANSLR[166.11]PGALFFSR[166.11].L "sp|P18887|XRCC1_HUMAN,tr|M0R1U8|M0R1U8_HUMAN,tr|M0R0D2|M0R0D2_HUMAN,tr|M0QYS5|M0QYS5_HUMAN,tr|F5H8D7|F5H8D7_HUMAN,tr|M0QZ96|M0QZ96_HUMAN" 6 2279.1541 1.07 105281 19448 4 2279.159565 570.7958 DNA repair protein XRCC1 OS=Homo sapiens OX=9606 GN=XRCC1 PE=1 SV=2 4.87 3163.3 - 587505 - - - 2.4198 - 3.144 0.449 - 285.2 1 2 1 0.0055 20 0 0 0 2.10E+07 1.96E+07 - - - 3.5155 1 221125_WJC_METTL3_EV_vs_WT_F07.19454.19454.3 2.30E-15 24/88 R.AHEVGAQGGPPVAQVEQDLPISR.E sp|Q14676|MDC1_HUMAN 1 2354.1979 1.92 105285 19454 3 2354.199336 785.7399 Mediator of DNA damage checkpoint protein 1 OS=Homo sapiens OX=9606 GN=MDC1 PE=1 SV=3 4.65 3164.1 - 502341 - - - 0.6219 - 4.633 0.715 - 650.8 1 2 0 0.0015 23 0 0 0 3.49E+07 1.81E+07 - - - 10.108 1 221125_WJC_METTL3_EV_vs_WT_F07.19455.19455.3 2.11E-09 19/96 R.VGETFHASQPSLTVDGFTDPSNSER[166.11].F "sp|Q15796|SMAD2_HUMAN,tr|B7Z5N5|B7Z5N5_HUMAN" 2 2687.2339 0.94 105286 19455 3 2687.235555 896.7519 Mothers against decapentaplegic homolog 2 OS=Homo sapiens OX=9606 GN=SMAD2 PE=1 SV=1 4.31 3164.2 - 856487 - - - 0.6259 - 2.954 0.653 - 214.9 1 2 0 0.0017 25 0 0 0 5.50E+07 5.84E+07 - - - 8.3118 0.9952 221125_WJC_METTL3_EV_vs_WT_F07.19456.19456.2 1.40E-06 16-Dec L.FDDFSHYEK[136.11].R sp|Q9Y5A9|YTHD2_HUMAN 1 1194.5073 1.29 105287 19456 2 1194.507109 598.2609 YTH domain-containing family protein 2 OS=Homo sapiens OX=9606 GN=YTHDF2 PE=1 SV=2 4.54 3164.3 - 822728 - - - -0.1632 - 2.322 0.574 - 325.1 1 1 0 -0.0002 9 0 0 0 1.33E+08 1.03E+08 - - - 5.7177 0.8705 221125_WJC_METTL3_EV_vs_WT_F07.19457.19457.2 0.00514 22-Dec L.ADAEQRGEHALK.D sp|P35908|K22E_HUMAN 1 1323.6531 999 105288 19457 2 1323.651991 662.8338 "Keratin, type II cytoskeletal 2 epidermal OS=Homo sapiens OX=9606 GN=KRT2 PE=1 SV=2" 5.45 3164.4 - 709636 - - - -0.8582 - 2.396 0.376 - 354.4 1 1 1 -0.0011 12 0 0 0 3.07E+07 0.00E+00 - - - 4.1169 1 221125_WJC_METTL3_EV_vs_WT_F07.19458.19458.3 1.75E-09 20/108 K.STNVIVDSGGGLLKPTVASQNQNLPVAK.L "tr|H0YE97|H0YE97_HUMAN,tr|H0YD48|H0YD48_HUMAN,tr|H0YEY8|H0YEY8_HUMAN,tr|H0YEF7|H0YEF7_HUMAN,tr|H0YEH1|H0YEH1_HUMAN" 5 2806.5189 3.84 105289 19458 3 2806.520376 936.5136 Phosphatidylinositol-binding clathrin assembly protein (Fragment) OS=Homo sapiens OX=9606 GN=PICALM PE=1 SV=1 8.31 3164.6 - 592031 - - - 0.5359 - 4.155 0.632 - 345.3 1 2 0 0.0015 28 0 0 0 2.97E+07 7.72E+06 - - - 8.8626 1 221125_WJC_METTL3_EV_vs_WT_F07.19459.19459.2 9.49E-07 16/26 K.HTTSIFDDFSHYEK.R sp|Q9Y5A9|YTHD2_HUMAN 1 1725.7635 1.31 105290 19459 2 1725.765908 863.889 YTH domain-containing family protein 2 OS=Homo sapiens OX=9606 GN=YTHDF2 PE=1 SV=2 5.21 3164.7 - 392429 - - - 1.4156 - 3.637 0.679 - 647.9 1 2 0 0.0024 14 0 0 0 7.18E+07 5.49E+07 - - - 7.2954 1 221125_WJC_METTL3_EV_vs_WT_F07.19462.19462.2 4.19E-08 15/26 K.HTTSIFDDFSHYEK[136.11].R sp|Q9Y5A9|YTHD2_HUMAN 1 1733.7777 1.31 105291 19462 2 1733.773631 867.8961 YTH domain-containing family protein 2 OS=Homo sapiens OX=9606 GN=YTHDF2 PE=1 SV=2 5.21 3165.1 - 788800 - - - -2.3267 - 3.426 0.693 - 567.5 1 2 0 -0.004 14 0 0 0 7.18E+07 5.49E+07 - - - 7.2484 1 221125_WJC_METTL3_EV_vs_WT_F07.19464.19464.4 1.98E-08 19/138 R.ATFHTPFSHLGQSPEGC[160.03]SSYTFPK.L "sp|O75521|ECI2_HUMAN,tr|A0A0C4DGA2|A0A0C4DGA2_HUMAN" 2 2682.2173 0.89 105293 19464 4 2682.212429 671.5616 Enoyl-CoA delta isomerase 2 OS=Homo sapiens OX=9606 GN=ECI2 PE=1 SV=4 6.95 3165.3 - 1.30E+06 - - - -1.8112 - 3.026 0.615 - 182.8 1 2 0 -0.0049 24 0 0 0 4.41E+07 4.97E+07 - - - 4.933 0.9997 221125_WJC_METTL3_EV_vs_WT_F07.19465.19465.4 0.00863 18/84 K.LSTDDLNSLIAHAHR[166.11].R "sp|Q16891|MIC60_HUMAN,tr|B9A067|B9A067_HUMAN,tr|C9J406|C9J406_HUMAN,tr|H7C463|H7C463_HUMAN" 4 1671.8568 1.34 105294 19465 4 1671.851968 418.9715 MICOS complex subunit MIC60 OS=Homo sapiens OX=9606 GN=IMMT PE=1 SV=1 5.98 3165.5 - 386923 - - - -2.8914 - 3.277 0.402 - 441.2 1 2 0 -0.0048 15 0 0 0 3.90E+07 2.91E+07 - - - 3.1484 0.9999 221125_WJC_METTL3_EV_vs_WT_F07.19469.19469.3 6.53E-05 13/92 K.EEMSQLTGQNSGDVNVEINVAPGK.D "sp|P35527|K1C9_HUMAN,tr|K7EQQ3|K7EQQ3_HUMAN" 2 2515.186 999 105296 19469 3 2515.182985 839.4026 "Keratin, type I cytoskeletal 9 OS=Homo sapiens OX=9606 GN=KRT9 PE=1 SV=3" 4 3166 - 632684 - - - -1.217 - 2.127 0.477 - 107.2 1 2 0 -0.0031 24 0 0 0 2.16E+08 0.00E+00 - - - 5.6101 1 221125_WJC_METTL3_EV_vs_WT_F07.19475.19475.4 2.27E-06 18/84 K.LSTDDLNSLIAHAHR.R "sp|Q16891|MIC60_HUMAN,tr|B9A067|B9A067_HUMAN,tr|C9J406|C9J406_HUMAN,tr|H7C463|H7C463_HUMAN" 4 1661.8485 1.34 105300 19475 4 1661.848711 416.4694 MICOS complex subunit MIC60 OS=Homo sapiens OX=9606 GN=IMMT PE=1 SV=1 5.98 3166.8 - 758244 - - - 0.1077 - 3.625 0.526 - 442.1 1 2 0 0.0002 15 0 0 0 3.90E+07 2.91E+07 - - - 4.2651 0.9855 221125_WJC_METTL3_EV_vs_WT_F07.19476.19476.2 1.98E-05 14-Sep F.DDFSHYEK.R sp|Q9Y5A9|YTHD2_HUMAN 1 1039.4247 1.47 105301 19476 2 1039.423062 520.7196 YTH domain-containing family protein 2 OS=Homo sapiens OX=9606 GN=YTHDF2 PE=1 SV=2 4.54 3166.9 - 1.83E+06 - - - -1.5663 - 1.836 0.488 - 284.5 1 1 0 -0.0016 8 0 0 0 7.17E+07 4.87E+07 - - - 4.4773 0.9999 221125_WJC_METTL3_EV_vs_WT_F07.19478.19478.4 2.19E-07 19/120 R.DSFDDRGPSLNPVLDYDHGSR.S "sp|P43243|MATR3_HUMAN,tr|A8MXP9|A8MXP9_HUMAN,tr|D6R991|D6R991_HUMAN,tr|A0A0R4J2E8|A0A0R4J2E8_HUMAN,tr|D6REM6|D6REM6_HUMAN" 5 2361.0622 1.77 105303 19478 4 2361.060243 591.2728 Matrin-3 OS=Homo sapiens OX=9606 GN=MATR3 PE=1 SV=2 4.28 3167.1 - 567293 - - - -0.8145 - 3.228 0.564 - 262.9 1 2 1 -0.0019 21 0 0 0 3.24E+07 1.84E+07 - - - 4.522 1 221125_WJC_METTL3_EV_vs_WT_F07.19479.19479.2 4.01E-08 15/34 K.NVQDAIADAEQRGEHALK.D sp|P35908|K22E_HUMAN 1 1963.9712 999 105304 19479 2 1963.966514 982.9929 "Keratin, type II cytoskeletal 2 epidermal OS=Homo sapiens OX=9606 GN=KRT2 PE=1 SV=2" 4.75 3167.2 - 426266 - - - -2.3692 - 3.19 0.569 - 428.4 1 2 1 -0.0047 18 0 0 0 1.11E+07 0.00E+00 - - - 6.0941 0.9938 221125_WJC_METTL3_EV_vs_WT_F07.19485.19485.3 7.35E-06 14/32 L.FDDFSHYEK[136.11].R sp|Q9Y5A9|YTHD2_HUMAN 1 1194.5073 1.46 105308 19485 3 1194.504244 399.1764 YTH domain-containing family protein 2 OS=Homo sapiens OX=9606 GN=YTHDF2 PE=1 SV=2 4.54 3168 - 1.09E+06 - - - -2.5617 - 2.107 0.552 - 152.8 1 1 0 -0.0031 9 0 0 0 3.16E+07 2.16E+07 - - - 6.9395 0.9979 221125_WJC_METTL3_EV_vs_WT_F07.19486.19486.3 0.000118 15/32 L.FDDFSHYEK.R sp|Q9Y5A9|YTHD2_HUMAN 1 1186.4931 1.46 105309 19486 3 1186.493135 396.505 YTH domain-containing family protein 2 OS=Homo sapiens OX=9606 GN=YTHDF2 PE=1 SV=2 4.54 3168.1 - 1.01E+06 - - - 0.0261 - 2.546 0.513 - 180.7 1 1 0 0 9 0 0 0 3.15E+07 2.16E+07 - - - 7.0759 1 221125_WJC_METTL3_EV_vs_WT_F07.19488.19488.3 3.74E-08 19/56 K.LSTDDLNSLIAHAHR[166.11].R "sp|Q16891|MIC60_HUMAN,tr|B9A067|B9A067_HUMAN,tr|C9J406|C9J406_HUMAN,tr|H7C463|H7C463_HUMAN" 4 1671.8568 0.99 105311 19488 3 1671.856028 558.2929 MICOS complex subunit MIC60 OS=Homo sapiens OX=9606 GN=IMMT PE=1 SV=1 5.98 3168.4 - 372964 - - - -0.463 - 3.355 0.559 - 688.3 1 2 0 -0.0008 15 0 0 0 1.87E+07 1.88E+07 - - - 7.9306 0.9786 221125_WJC_METTL3_EV_vs_WT_F07.19491.19491.2 0.000619 14-Sep F.DDFSHYEK[136.11].R sp|Q9Y5A9|YTHD2_HUMAN 1 1047.4389 1.47 105312 19491 2 1047.437996 524.7267 YTH domain-containing family protein 2 OS=Homo sapiens OX=9606 GN=YTHDF2 PE=1 SV=2 4.54 3168.8 - 1.72E+06 - - - -0.8535 - 1.866 0.348 - 267.9 1 1 0 -0.0009 8 0 0 0 7.17E+07 4.86E+07 - - - 3.4924 0.9962 221125_WJC_METTL3_EV_vs_WT_F07.19493.19493.4 3.54E-08 18/144 K.TAHLDEEVNK[136.11]GDILVVATGQPEMVK[136.11].G "sp|P11586|C1TC_HUMAN,tr|F5H2F4|F5H2F4_HUMAN,tr|V9GZ78|V9GZ78_HUMAN,tr|V9GYY3|V9GYY3_HUMAN" 4 2708.4026 1.43 105314 19493 4 2708.387483 678.1079 "C-1-tetrahydrofolate synthase, cytoplasmic OS=Homo sapiens OX=9606 GN=MTHFD1 PE=1 SV=4" 4.5 3169 - 555546 - - - -5.5749 - 3.548 0.465 - 185.5 1 2 1 -0.0151 25 0 0 0 8.07E+07 5.64E+07 - - - 3.672 0.9941 221125_WJC_METTL3_EV_vs_WT_F07.19497.19497.3 2.00E-09 18/84 K.GILGYTEHQVVSSDFNSDTHSS.T "sp|P04406|G3P_HUMAN,tr|E7EUT5|E7EUT5_HUMAN" 2 2379.0615 - 105315 19497 3 2379.053132 794.0278 Glyceraldehyde-3-phosphate dehydrogenase OS=Homo sapiens OX=9606 GN=GAPDH PE=1 SV=3 4.52 3169.6 - 859154 - - - -3.5165 - 3.424 0.607 - 363 1 1 0 -0.0084 22 0 0 0 - - - - - 8.2232 1 221125_WJC_METTL3_EV_vs_WT_F07.19501.19501.3 1.77E-07 15/56 K.LSTDDLNSLIAHAHR.R "sp|Q16891|MIC60_HUMAN,tr|B9A067|B9A067_HUMAN,tr|C9J406|C9J406_HUMAN,tr|H7C463|H7C463_HUMAN" 4 1661.8485 1.02 105317 19501 3 1661.848122 554.9568 MICOS complex subunit MIC60 OS=Homo sapiens OX=9606 GN=IMMT PE=1 SV=1 5.98 3170 - 820963 - - - -0.2467 - 2.941 0.533 - 271 1 2 0 -0.0004 15 0 0 0 1.87E+07 1.83E+07 - - - 7.2972 1 221125_WJC_METTL3_EV_vs_WT_F07.19504.19504.3 2.39E-08 15/60 K.RGFGFVTFDDHDPVDK.L "sp|P22626|ROA2_HUMAN,tr|A0A7I2V4N0|A0A7I2V4N0_HUMAN,tr|A0A024RA28|A0A024RA28_HUMAN,tr|A0A7I2V4N1|A0A7I2V4N1_HUMAN,tr|A0A7I2V4I6|A0A7I2V4I6_HUMAN,tr|A0A087WUI2|A0A087WUI2_HUMAN,tr|A0A7I2V4S4|A0A7I2V4S4_HUMAN,tr|A0A7I2V323|A0A7I2V323_HUMAN,tr|A0A7I2V3P1|A0A7I2V3P1_HUMAN,tr|A0A7I2V3P7|A0A7I2V3P7_HUMAN" 10 1850.8588 999 105319 19504 3 1850.858473 617.9602 Heterogeneous nuclear ribonucleoproteins A2\B1 OS=Homo sapiens OX=9606 GN=HNRNPA2B1 PE=1 SV=2 4.56 3170.4 - 326184 - - - -0.1567 - 2.987 0.587 - 350 1 2 0 -0.0003 16 0 0 0 6.19E+06 0.00E+00 - - - 7.8921 0.9999 221125_WJC_METTL3_EV_vs_WT_F07.19508.19508.4 6.57E-09 21/144 K.TAHLDEEVNKGDILVVATGQPEMVK.G "sp|P11586|C1TC_HUMAN,tr|F5H2F4|F5H2F4_HUMAN,tr|V9GZ78|V9GZ78_HUMAN,tr|V9GYY3|V9GYY3_HUMAN" 4 2692.3742 1.43 105321 19508 4 2692.370806 674.1008 "C-1-tetrahydrofolate synthase, cytoplasmic OS=Homo sapiens OX=9606 GN=MTHFD1 PE=1 SV=4" 4.5 3170.9 - 1.86E+06 - - - -1.2539 - 3.755 0.583 - 252.7 1 2 1 -0.0034 25 0 0 0 8.07E+07 5.63E+07 - - - 4.7204 1 221125_WJC_METTL3_EV_vs_WT_F07.19512.19512.2 1.70E-17 17/46 K.EEMSQLTGQNSGDVNVEINVAPGK.D "sp|P35527|K1C9_HUMAN,tr|K7EQQ3|K7EQQ3_HUMAN" 2 2515.186 999 105325 19512 2 2515.183133 1258.6003 "Keratin, type I cytoskeletal 9 OS=Homo sapiens OX=9606 GN=KRT9 PE=1 SV=3" 4 3171.3 - 466382 - - - -1.1582 - 3.482 0.803 - 407.2 1 2 0 -0.0029 24 0 0 0 1.31E+07 0.00E+00 - - - 8.0383 1 221125_WJC_METTL3_EV_vs_WT_F07.19516.19516.3 1.17E-08 24/80 R.QVQSLTC[160.03]EVDALK[136.11]GTNESLER[166.11].Q "sp|P08670|VIME_HUMAN,tr|B0YJC5|B0YJC5_HUMAN,tr|B0YJC4|B0YJC4_HUMAN" 3 2394.1816 1.67 105326 19516 3 2394.184021 799.0678 Vimentin OS=Homo sapiens OX=9606 GN=VIM PE=1 SV=4 4.41 3171.8 - 1.03E+06 - - - 1.0221 - 4.107 0.59 - 605.2 1 2 1 0.0024 21 0 0 0 2.34E+08 1.40E+08 - - - 8.5041 0.9922 221125_WJC_METTL3_EV_vs_WT_F07.19517.19517.3 0.00395 17/52 R.K[136.11]HAASDVDLEIESL.L "sp|Q86U44|MTA70_HUMAN,tr|F5H6D8|F5H6D8_HUMAN,tr|H0YFV6|H0YFV6_HUMAN,tr|B4DTN4|B4DTN4_HUMAN" 4 1533.7766 0.12 105327 19517 3 1533.77288 512.2661 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 4.31 3171.9 - 735126 - - - -2.4267 - 3.188 0.437 - 484.6 1 1 0 -0.0037 14 0 0 0 1.82E+06 1.46E+07 - - - 6.4922 0.9998 221125_WJC_METTL3_EV_vs_WT_F07.19518.19518.2 3.25E-06 20-Dec K.WEGLVYAPPGK.E "sp|Q9Y2W1|TR150_HUMAN,tr|A0A3B3ITZ9|A0A3B3ITZ9_HUMAN" 2 1215.6288 4.53 105328 19518 2 1215.626463 608.8217 Thyroid hormone receptor-associated protein 3 OS=Homo sapiens OX=9606 GN=THRAP3 PE=1 SV=2 6 3172.1 - 603739 - - - -1.9299 - 2.155 0.526 - 401.2 1 2 0 -0.0023 11 0 0 0 2.12E+07 4.68E+06 - - - 5.0024 1 221125_WJC_METTL3_EV_vs_WT_F07.19524.19524.3 3.24E-13 18/96 K.TAHLDEEVNKGDILVVATGQPEMVK.G "sp|P11586|C1TC_HUMAN,tr|F5H2F4|F5H2F4_HUMAN,tr|V9GZ78|V9GZ78_HUMAN,tr|V9GYY3|V9GYY3_HUMAN" 4 2692.3742 1.94 105331 19524 3 2692.371785 898.4653 "C-1-tetrahydrofolate synthase, cytoplasmic OS=Homo sapiens OX=9606 GN=MTHFD1 PE=1 SV=4" 4.5 3172.8 - 580509 - - - -0.8903 - 3.918 0.7 - 343.2 1 2 1 -0.0024 25 0 0 0 1.44E+07 7.44E+06 - - - 9.4854 1 221125_WJC_METTL3_EV_vs_WT_F07.19525.19525.3 2.71E-09 26/80 R.QVQSLTC[160.03]EVDALKGTNESLER.Q "sp|P08670|VIME_HUMAN,tr|B0YJC5|B0YJC5_HUMAN,tr|B0YJC4|B0YJC4_HUMAN" 3 2376.1591 1.67 105332 19525 3 2376.155178 793.0603 Vimentin OS=Homo sapiens OX=9606 GN=VIM PE=1 SV=4 4.41 3172.9 - 2.01E+06 - - - -1.6522 - 4.19 0.61 - 790.9 1 2 1 -0.0039 21 0 0 0 2.34E+08 1.40E+08 - - - 8.7746 1 221125_WJC_METTL3_EV_vs_WT_F07.19533.19533.4 2.97E-08 15/120 K.SWQGVTIYFSGHETPGEGEHK.L "sp|Q8IZH2|XRN1_HUMAN,tr|C9JCZ8|C9JCZ8_HUMAN" 2 2345.0713 1.37 105338 19533 4 2345.07042 587.2751 5'-3' exoribonuclease 1 OS=Homo sapiens OX=9606 GN=XRN1 PE=1 SV=1 5.31 3173.9 - 1.47E+06 - - - -0.3646 - 3.453 0.496 - 123.3 1 2 0 -0.0009 21 0 0 0 2.05E+07 1.49E+07 - - - 3.9527 1 221125_WJC_METTL3_EV_vs_WT_F07.19535.19535.3 7.62E-15 25/88 R.AHEVGAQGGPPVAQVEQDLPISR[166.11].E sp|Q14676|MDC1_HUMAN 1 2364.2061 1.89 105340 19535 3 2364.200686 789.076 Mediator of DNA damage checkpoint protein 1 OS=Homo sapiens OX=9606 GN=MDC1 PE=1 SV=3 4.65 3174.2 - 526811 - - - -2.3078 - 4.438 0.65 - 719.2 1 2 0 -0.0055 23 0 0 0 3.39E+07 1.80E+07 - - - 9.2813 1 221125_WJC_METTL3_EV_vs_WT_F07.19537.19537.2 1.29E-08 15/28 K.HTDESLGDC[160.03]SFLNTC[160.03].F "sp|Q86U44|MTA70_HUMAN,tr|H0YFV6|H0YFV6_HUMAN" 2 1754.6876 - 105342 19537 2 1755.688629 878.3511 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 4.02 3174.4 - 472246 - - - 570.4884 - 3.201 0.747 - 621.9 1 1 0 1.001 15 0 0 0 - - - - - 7.1044 1 221125_WJC_METTL3_EV_vs_WT_F07.19541.19541.3 1.93E-13 18/96 K.TAHLDEEVNK[136.11]GDILVVATGQPEMVK[136.11].G "sp|P11586|C1TC_HUMAN,tr|F5H2F4|F5H2F4_HUMAN,tr|V9GZ78|V9GZ78_HUMAN,tr|V9GYY3|V9GYY3_HUMAN" 4 2708.4026 1.94 105344 19541 3 2708.399828 903.8081 "C-1-tetrahydrofolate synthase, cytoplasmic OS=Homo sapiens OX=9606 GN=MTHFD1 PE=1 SV=4" 4.5 3174.9 - 518951 - - - -1.0168 - 3.731 0.65 - 374.1 1 2 1 -0.0028 25 0 0 0 1.44E+07 7.44E+06 - - - 8.8153 0.9997 221125_WJC_METTL3_EV_vs_WT_F07.19542.19542.4 3.45E-09 24/126 R.LQLLTGEHRPEDEEELEKELYR.E sp|Q13505|MTX1_HUMAN 1 2725.3559 1.6 105345 19542 4 2725.363979 682.3462 Metaxin-1 OS=Homo sapiens OX=9606 GN=MTX1 PE=1 SV=3 4.42 3175.1 - 861952 - - - 2.9684 - 4.665 0.527 - 414.2 1 2 1 0.0081 22 0 0 0 2.27E+07 1.42E+07 - - - 4.3147 0.9754 221125_WJC_METTL3_EV_vs_WT_F07.19543.19543.3 0.000786 Nov-92 S.LNQQGAHSALSSASTSSHNLQSIF.- tr|D6RBS2|D6RBS2_HUMAN 1 2484.1993 - 105346 19543 3 2484.203407 829.0737 Matrin-3 (Fragment) OS=Homo sapiens OX=9606 GN=MATR3 PE=1 SV=1 6.92 3175.2 - 723830 - - - 1.6416 - 2.441 0.375 - 91.9 1 1 0 0.0041 24 0 0 0 - - - - - 4.7925 1 221125_WJC_METTL3_EV_vs_WT_F07.19547.19547.4 4.13E-09 19/120 K.SWQGVTIYFSGHETPGEGEHK[136.11].L "sp|Q8IZH2|XRN1_HUMAN,tr|C9JCZ8|C9JCZ8_HUMAN" 2 2353.0855 1.37 105348 19547 4 2353.085435 589.2786 5'-3' exoribonuclease 1 OS=Homo sapiens OX=9606 GN=XRN1 PE=1 SV=1 5.31 3175.7 - 850182 - - - -0.017 - 3.776 0.59 - 221.7 1 2 0 0 21 0 0 0 2.05E+07 1.49E+07 - - - 4.8007 1 221125_WJC_METTL3_EV_vs_WT_F07.19550.19550.3 2.68E-14 24/76 K.TSAKEEDAFHFVSYVPVNGR.L "sp|Q9Y5K5|UCHL5_HUMAN,tr|H0Y4E0|H0Y4E0_HUMAN,tr|Q5LJA9|Q5LJA9_HUMAN,tr|H0Y6Y4|H0Y6Y4_HUMAN,tr|Q5LJB0|Q5LJB0_HUMAN,tr|Q5LJA5|Q5LJA5_HUMAN" 6 2252.0862 1.76 105351 19550 3 2252.085259 751.7027 Ubiquitin carboxyl-terminal hydrolase isozyme L5 OS=Homo sapiens OX=9606 GN=UCHL5 PE=1 SV=3 5.41 3176.1 - 881505 - - - -0.4161 - 4.051 0.664 - 673.2 1 2 1 -0.0009 20 0 0 0 6.52E+07 3.71E+07 - - - 9.3366 0.9999 221125_WJC_METTL3_EV_vs_WT_F07.19555.19555.4 6.57E-09 14/114 K.TSAK[136.11]EEDAFHFVSYVPVNGR[166.11].L "sp|Q9Y5K5|UCHL5_HUMAN,tr|H0Y4E0|H0Y4E0_HUMAN,tr|Q5LJA9|Q5LJA9_HUMAN,tr|H0Y6Y4|H0Y6Y4_HUMAN,tr|Q5LJB0|Q5LJB0_HUMAN,tr|Q5LJA5|Q5LJA5_HUMAN" 6 2270.1087 1.74 105354 19555 4 2270.109696 568.5344 Ubiquitin carboxyl-terminal hydrolase isozyme L5 OS=Homo sapiens OX=9606 GN=UCHL5 PE=1 SV=3 5.41 3176.8 - 2.49E+06 - - - 0.4537 - 2.601 0.613 - 83.7 1 2 1 0.001 20 0 0 0 1.62E+08 9.31E+07 - - - 4.8808 0.9999 221125_WJC_METTL3_EV_vs_WT_F07.19557.19557.4 6.23E-08 17/114 K.TSAKEEDAFHFVSYVPVNGR.L "sp|Q9Y5K5|UCHL5_HUMAN,tr|H0Y4E0|H0Y4E0_HUMAN,tr|Q5LJA9|Q5LJA9_HUMAN,tr|H0Y6Y4|H0Y6Y4_HUMAN,tr|Q5LJB0|Q5LJB0_HUMAN,tr|Q5LJA5|Q5LJA5_HUMAN" 6 2252.0862 1.76 105356 19557 4 2252.090609 564.0288 Ubiquitin carboxyl-terminal hydrolase isozyme L5 OS=Homo sapiens OX=9606 GN=UCHL5 PE=1 SV=3 5.41 3176.9 - 4.31E+06 - - - 1.9595 - 2.706 0.539 - 149.2 1 2 1 0.0044 20 0 0 0 1.64E+08 9.31E+07 - - - 4.249 1 221125_WJC_METTL3_EV_vs_WT_F07.19559.19559.3 2.35E-12 24/76 K.TSAK[136.11]EEDAFHFVSYVPVNGR[166.11].L "sp|Q9Y5K5|UCHL5_HUMAN,tr|H0Y4E0|H0Y4E0_HUMAN,tr|Q5LJA9|Q5LJA9_HUMAN,tr|H0Y6Y4|H0Y6Y4_HUMAN,tr|Q5LJB0|Q5LJB0_HUMAN,tr|Q5LJA5|Q5LJA5_HUMAN" 6 2270.1087 1.76 105358 19559 3 2270.114773 757.7102 Ubiquitin carboxyl-terminal hydrolase isozyme L5 OS=Homo sapiens OX=9606 GN=UCHL5 PE=1 SV=3 5.41 3177.2 - 896684 - - - 2.6902 - 4.4 0.636 - 720.7 1 2 1 0.0061 20 0 0 0 6.52E+07 3.71E+07 - - - 9.2235 0.776 221125_WJC_METTL3_EV_vs_WT_F07.19560.19560.3 1.49E-05 10/100 K.NGFSSVQATQLQTTQSVEGATGSAVK[136.11].S "sp|Q14157|UBP2L_HUMAN,tr|F8W726|F8W726_HUMAN" 2 2603.2918 0.65 105359 19560 3 2604.273759 868.7712 Ubiquitin-associated protein 2-like OS=Homo sapiens OX=9606 GN=UBAP2L PE=1 SV=2 6 3177.4 - 571045 - - - 377.184 - 2.226 0.471 - 83.1 1 2 0 0.9819 26 0 0 0 1.84E+06 2.83E+06 - - - 5.3602 0.9999 221125_WJC_METTL3_EV_vs_WT_F07.19561.19561.4 1.67E-05 12/108 R.GLLQDDAHPTLVTYADHSK[136.11].L "sp|Q86U44|MTA70_HUMAN,tr|F5H6D8|F5H6D8_HUMAN,tr|H0YFV6|H0YFV6_HUMAN,tr|B4DTN4|B4DTN4_HUMAN" 4 2088.0367 0.02 105360 19561 4 2088.036221 523.0165 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 5.13 3177.5 - 484617 - - - -0.2452 - 2.565 0.464 - 142.9 1 2 0 -0.0005 19 0 0 0 2.68E+05 1.52E+07 - - - 3.5832 0.9996 221125_WJC_METTL3_EV_vs_WT_F07.19563.19563.3 0.00169 Oct-72 R.GLLQDDAHPTLVTYADHSK[136.11].L "sp|Q86U44|MTA70_HUMAN,tr|F5H6D8|F5H6D8_HUMAN,tr|H0YFV6|H0YFV6_HUMAN,tr|B4DTN4|B4DTN4_HUMAN" 4 2088.0367 0.2 105362 19563 3 2088.033941 697.0195 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 5.13 3177.7 - 176947 - - - -1.3371 - 2.104 0.339 - 121.8 1 2 0 -0.0028 19 0 0 0 6.54E+05 3.32E+06 - - - 4.1462 0.846 221125_WJC_METTL3_EV_vs_WT_F07.19566.19566.2 0.671 16-Aug Q.LSVQEDVKI.- sp|P36896|ACV1B_HUMAN 1 1029.5706 475.93 105363 19566 2 1029.571376 515.7926 Activin receptor type-1B OS=Homo sapiens OX=9606 GN=ACVR1B PE=1 SV=1 4.37 3178.1 - 1.01E+06 - - - 0.7285 - 1.604 0.161 - 146.1 1 1 0 0.0008 9 0 0 0 2.81E+07 5.91E+04 - - - 1.5969 0.9999 221125_WJC_METTL3_EV_vs_WT_F07.19568.19568.4 1.96E-06 22/126 R.LQLLTGEHR[166.11]PEDEEELEK[136.11]ELYR[166.11].E sp|Q13505|MTX1_HUMAN 1 2753.3866 1.72 105365 19568 4 2753.391803 689.3539 Metaxin-1 OS=Homo sapiens OX=9606 GN=MTX1 PE=1 SV=3 4.42 3178.4 - 913784 - - - 1.8791 - 4.241 0.599 - 324.6 1 2 1 0.0052 22 0 0 0 2.75E+07 1.60E+07 - - - 4.911 1 221125_WJC_METTL3_EV_vs_WT_F07.19577.19577.4 5.14E-07 21/120 R.K[136.11]HPDADSLYVEEVDVGEIAPR[166.11].T "sp|Q12904|AIMP1_HUMAN,tr|A0A804HJ47|A0A804HJ47_HUMAN,tr|A0A5F9ZHC5|A0A5F9ZHC5_HUMAN" 3 2356.1666 1.34 105372 19577 4 2356.169697 590.0489 Aminoacyl tRNA synthase complex-interacting multifunctional protein 1 OS=Homo sapiens OX=9606 GN=AIMP1 PE=1 SV=2 4.29 3179.5 - 772593 - - - 1.325 - 3.908 0.547 - 361.5 1 2 0 0.0031 21 0 0 0 4.24E+07 3.17E+07 - - - 4.4369 0.9151 221125_WJC_METTL3_EV_vs_WT_F07.19578.19578.2 9.21 14-May K.NLYIISVK[136.11].G "sp|P62829|RL23_HUMAN,tr|J3KT29|J3KT29_HUMAN,tr|B9ZVP7|B9ZVP7_HUMAN,tr|C9JD32|C9JD32_HUMAN" 4 956.5786 1.18 105373 19578 2 956.579701 479.2966 60S ribosomal protein L23 OS=Homo sapiens OX=9606 GN=RPL23 PE=1 SV=1 8.59 3179.7 - 90664 - - - 1.1322 - 1.218 0.032 - 54.7 10 2 0 0.0011 8 0 0 0 1.48E+06 1.26E+06 - - - -0.5749 1 221125_WJC_METTL3_EV_vs_WT_F07.19581.19581.4 4.40E-11 21/120 R.KHPDADSLYVEEVDVGEIAPR.T "sp|Q12904|AIMP1_HUMAN,tr|A0A804HJ47|A0A804HJ47_HUMAN,tr|A0A5F9ZHC5|A0A5F9ZHC5_HUMAN" 3 2338.1441 1.32 105374 19581 4 2338.149881 585.5433 Aminoacyl tRNA synthase complex-interacting multifunctional protein 1 OS=Homo sapiens OX=9606 GN=AIMP1 PE=1 SV=2 4.29 3180.1 - 1.23E+06 - - - 2.4703 - 3.708 0.597 - 321.3 1 2 0 0.0058 21 0 0 0 4.26E+07 3.22E+07 - - - 4.854 0.9999 221125_WJC_METTL3_EV_vs_WT_F07.19583.19583.4 2.12E-06 16/156 R.EGAPIEPDPPVSHWKPEAVQYYEDGAR.L "sp|Q96HS1|PGAM5_HUMAN,tr|F5GXG4|F5GXG4_HUMAN" 2 3036.4254 1.81 105376 19583 4 3036.429167 760.1136 "Serine\threonine-protein phosphatase PGAM5, mitochondrial OS=Homo sapiens OX=9606 GN=PGAM5 PE=1 SV=2" 4.35 3180.3 - 848398 - - - 1.2518 - 2.897 0.453 - 130.5 1 2 0 0.0038 27 0 0 0 4.71E+07 2.60E+07 - - - 3.5007 0.9224 221125_WJC_METTL3_EV_vs_WT_F07.19588.19588.3 0.575 Jun-48 R.NILSVVGTDALKK.T sp|O43172|PRP4_HUMAN 1 1356.7977 4.26 105381 19588 3 1356.798254 453.2732 U4\U6 small nuclear ribonucleoprotein Prp4 OS=Homo sapiens OX=9606 GN=PRPF4 PE=1 SV=2 8.59 3181 - 129508 - - - 0.4334 - 1.111 0.159 - 41 1 2 0 0.0006 13 0 0 0 1.53E+06 3.59E+05 - - - 0.5979 1 221125_WJC_METTL3_EV_vs_WT_F07.19592.19592.3 1.73E-09 18/112 K.QGTAVEVEAESLDPTVKPVDVGGDEPEEK.V "sp|P49321|NASP_HUMAN,tr|E9PPR5|E9PPR5_HUMAN" 2 3023.4459 1.29 105383 19592 3 3023.453107 1008.8226 Nuclear autoantigenic sperm protein OS=Homo sapiens OX=9606 GN=NASP PE=1 SV=2 3.84 3181.5 - 337974 - - - 2.3883 - 3.372 0.646 - 194.2 1 2 0 0.0072 29 0 0 0 7.31E+06 5.67E+06 - - - 8.5367 1 221125_WJC_METTL3_EV_vs_WT_F07.19593.19593.4 5.92E-09 23/114 K.K[136.11]PVVDC[160.03]VVSVPC[160.03]FYTDAER[166.11]R[166.11].S "sp|P34932|HSP74_HUMAN,tr|A0A087WTS8|A0A087WTS8_HUMAN,tr|A0A087WYC1|A0A087WYC1_HUMAN" 3 2424.1924 0.29 105384 19593 4 2424.186852 607.0554 Heat shock 70 kDa protein 4 OS=Homo sapiens OX=9606 GN=HSPA4 PE=1 SV=4 6.11 3181.6 - 1.33E+06 - - - -2.2997 - 4.084 0.573 - 298.9 1 2 0 -0.0056 20 0 0 0 1.14E+07 3.96E+07 - - - 4.6823 0.9995 221125_WJC_METTL3_EV_vs_WT_F07.19596.19596.3 4.14E-05 Nov-48 R.SIFDHIKLPQASK.S "sp|Q9NYF8|BCLF1_HUMAN,tr|E9PKI6|E9PKI6_HUMAN,tr|A0A1W2PQ43|A0A1W2PQ43_HUMAN,tr|E9PK91|E9PK91_HUMAN,tr|E9PJA7|E9PJA7_HUMAN,tr|E9PK09|E9PK09_HUMAN,tr|E9PQN2|E9PQN2_HUMAN" 7 1482.8195 2.12 105387 19596 3 1482.821987 495.2804 Bcl-2-associated transcription factor 1 OS=Homo sapiens OX=9606 GN=BCLAF1 PE=1 SV=2 8.33 3182 - 261314 - - - 1.7015 - 1.77 0.488 - 80 1 2 1 0.0025 13 0 0 0 1.05E+08 4.96E+07 - - - 5.5281 0.9907 221125_WJC_METTL3_EV_vs_WT_F07.19597.19597.3 3.77E-09 15/104 T.SFGTETSNSGTLPQSSAVGSAFTQDTR.S "sp|Q8ND56|LS14A_HUMAN,tr|A0A140TA76|A0A140TA76_HUMAN,tr|K7EMZ9|K7EMZ9_HUMAN" 3 2732.2525 0.65 105388 19597 3 2732.264033 911.7581 Protein LSM14 homolog A OS=Homo sapiens OX=9606 GN=LSM14A PE=1 SV=3 4.37 3182.2 - 154852 - - - 4.2042 - 3.163 0.645 - 148.8 1 1 0 0.0115 27 0 0 0 6.06E+06 9.32E+06 - - - 8.3772 0.9989 221125_WJC_METTL3_EV_vs_WT_F07.19601.19601.4 0.0139 16/162 R.APVSALPLAPNHLGGGAVVLGAESHASK.D "sp|Q13190|STX5_HUMAN,tr|H7C3X5|H7C3X5_HUMAN" 2 2619.4133 1.31 105390 19601 4 2619.420153 655.8606 Syntaxin-5 OS=Homo sapiens OX=9606 GN=STX5 PE=1 SV=2 6.96 3182.7 - 542516 - - - 2.622 - 2.979 0.326 - 93.8 1 2 0 0.0069 28 0 0 0 6.76E+06 5.17E+06 - - - 2.4005 1 221125_WJC_METTL3_EV_vs_WT_F07.19602.19602.4 2.32E-10 27/132 R.FSGVPDRFSGSGSGTDFTLKISR.V "sp|A2NJV5|KV229_HUMAN,sp|A0A075B6S2|KVD29_HUMAN,sp|A0A0A0MRZ7|KVD26_HUMAN" 3 2417.1975 712.81 105391 19602 4 2417.199243 605.3067 Immunoglobulin kappa variable 2-29 OS=Homo sapiens OX=9606 GN=IGKV2-29 PE=3 SV=2 8.75 3182.8 - 1.49E+06 - - - 0.7054 - 4.018 0.64 - 611.4 1 2 2 0.0017 23 0 0 0 5.28E+07 7.41E+04 - - - 5.2467 0.9991 221125_WJC_METTL3_EV_vs_WT_F07.19604.19604.4 0.00366 9/102 R.SIIQQHNLETLENDIKGK.L sp|O00443|P3C2A_HUMAN 1 2079.096 1.01 105393 19604 4 2079.098593 520.7813 Phosphatidylinositol 4-phosphate 3-kinase C2 domain-containing subunit alpha OS=Homo sapiens OX=9606 GN=PIK3C2A PE=1 SV=2 5.42 3183.1 - 303114 - - - 1.2313 - 1.558 0.386 - 34.2 1 2 1 0.0026 18 0 0 0 3.03E+06 3.01E+06 - - - 2.7369 1 221125_WJC_METTL3_EV_vs_WT_F07.19610.19610.3 1.52E-11 19/72 K.SSGDVHLSISSDVSTFTTR.T "sp|Q13492|PICAL_HUMAN,tr|H0YD48|H0YD48_HUMAN,tr|H0YEF7|H0YEF7_HUMAN" 3 1994.9545 1.76 105397 19610 3 1994.96208 665.9921 Phosphatidylinositol-binding clathrin assembly protein OS=Homo sapiens OX=9606 GN=PICALM PE=1 SV=2 5.19 3183.8 - 792198 - - - 3.7931 - 4.009 0.636 - 372.7 1 2 0 0.0076 19 0 0 0 1.70E+07 9.64E+06 - - - 9.04 1 221125_WJC_METTL3_EV_vs_WT_F07.19611.19611.4 1.37E-06 14/156 R.EGAPIEPDPPVSHWK[136.11]PEAVQYYEDGAR[166.11].L "sp|Q96HS1|PGAM5_HUMAN,tr|F5GXG4|F5GXG4_HUMAN" 2 3054.4478 2.1 105398 19611 4 3054.454855 764.6192 "Serine\threonine-protein phosphatase PGAM5, mitochondrial OS=Homo sapiens OX=9606 GN=PGAM5 PE=1 SV=2" 4.35 3183.9 - 742795 - - - 2.298 - 2.952 0.543 - 104 1 2 0 0.007 27 0 0 0 4.65E+07 2.22E+07 - - - 4.289 0.9999 221125_WJC_METTL3_EV_vs_WT_F07.19613.19613.4 4.02E-06 14/126 R.SLSEINKPNFYNNDFDDDFSHR.S "sp|Q5QJE6|TDIF2_HUMAN,tr|J3KP30|J3KP30_HUMAN" 2 2673.1732 3.35 105400 19613 4 2673.174383 669.3006 Deoxynucleotidyltransferase terminal-interacting protein 2 OS=Homo sapiens OX=9606 GN=DNTTIP2 PE=1 SV=2 4.35 3184.2 - 493325 - - - 0.4523 - 2.805 0.461 - 95 1 2 0 0.0012 22 0 0 0 8.36E+06 2.49E+06 - - - 3.5757 1 221125_WJC_METTL3_EV_vs_WT_F07.19614.19614.3 3.13E-07 15/72 K.SIEEQLGTEIKPIPSNIDK.S sp|P26196|DDX6_HUMAN 1 2110.1158 1.2 105401 19614 3 2110.119894 704.3792 Probable ATP-dependent RNA helicase DDX6 OS=Homo sapiens OX=9606 GN=DDX6 PE=1 SV=2 4.41 3184.3 - 473085 - - - 1.9568 - 2.724 0.543 - 137.5 1 2 0 0.0041 19 0 0 0 6.55E+06 5.46E+06 - - - 7.0547 1 221125_WJC_METTL3_EV_vs_WT_F07.19615.19615.3 3.85E-05 18/112 K.QGTAVEVEAESLDPTVK[136.11]PVDVGGDEPEEK[136.11].V "sp|P49321|NASP_HUMAN,tr|E9PPR5|E9PPR5_HUMAN" 2 3039.4743 1.29 105402 19615 3 3039.474451 1014.1654 Nuclear autoantigenic sperm protein OS=Homo sapiens OX=9606 GN=NASP PE=1 SV=2 3.84 3184.4 - 447841 - - - 0.0543 - 3.32 0.603 - 248.4 1 2 0 0.0002 29 0 0 0 7.31E+06 5.67E+06 - - - 8.0235 1 221125_WJC_METTL3_EV_vs_WT_F07.19620.19620.3 1.04E-10 25/80 K.TATQTGHTLLEDYQIVDNSQR.E sp|Q8N0X7|SPART_HUMAN 1 2389.151 1.1 105405 19620 3 2389.154063 797.3909 Spartin OS=Homo sapiens OX=9606 GN=SPART PE=1 SV=1 4.53 3185.1 - 1.64E+06 - - - 1.2896 - 4.545 0.615 - 700.3 1 2 0 0.0031 21 0 0 0 1.19E+08 1.08E+08 - - - 9.0256 1 221125_WJC_METTL3_EV_vs_WT_F07.19623.19623.3 7.84E-14 22/80 R.KHPDADSLYVEEVDVGEIAPR.T "sp|Q12904|AIMP1_HUMAN,tr|A0A804HJ47|A0A804HJ47_HUMAN,tr|A0A5F9ZHC5|A0A5F9ZHC5_HUMAN" 3 2338.1441 2.15 105408 19623 3 2338.145194 780.3886 Aminoacyl tRNA synthase complex-interacting multifunctional protein 1 OS=Homo sapiens OX=9606 GN=AIMP1 PE=1 SV=2 4.29 3185.4 - 976296 - - - 0.4658 - 4.535 0.525 - 610.7 1 2 0 0.0011 21 0 0 0 1.94E+07 9.06E+06 - - - 8.0175 0.9996 221125_WJC_METTL3_EV_vs_WT_F07.19624.19624.4 0.000176 14/114 K.QDSSPHLTSQR[166.11]PVDMVQLLK[136.11].K sp|Q96T58|MINT_HUMAN 1 2296.1964 1.28 105409 19624 4 2296.202 575.0564 Msx2-interacting protein OS=Homo sapiens OX=9606 GN=SPEN PE=1 SV=1 6.75 3185.6 - 805320 - - - 2.4231 - 2.406 0.388 - 124.6 1 2 0 0.0056 20 0 0 0 1.69E+07 1.33E+07 - - - 2.8951 0.9373 221125_WJC_METTL3_EV_vs_WT_F07.19626.19626.4 2.99E-09 15/150 S.SDFNSDTHSSTFDAGAGIALNDHFVK[136.11].L "sp|P04406|G3P_HUMAN,tr|E7EUT5|E7EUT5_HUMAN" 2 2760.2507 1.15 105411 19626 4 2761.257175 691.07 Glyceraldehyde-3-phosphate dehydrogenase OS=Homo sapiens OX=9606 GN=GAPDH PE=1 SV=3 4.54 3185.8 - 498545 - - - 364.631 - 2.363 0.611 - 111.6 1 1 0 1.0065 26 0 0 0 5.35E+06 4.65E+06 - - - 4.5366 1 221125_WJC_METTL3_EV_vs_WT_F07.19634.19634.3 3.03E-13 25/88 R.FSGVPDRFSGSGSGTDFTLKISR.V "sp|A2NJV5|KV229_HUMAN,sp|A0A075B6S2|KVD29_HUMAN,sp|A0A0A0MRZ7|KVD26_HUMAN" 3 2417.1975 1.35 105416 19634 3 2417.20308 806.7398 Immunoglobulin kappa variable 2-29 OS=Homo sapiens OX=9606 GN=IGKV2-29 PE=3 SV=2 8.75 3186.9 - 597045 - - - 2.2927 - 3.928 0.705 - 540.8 1 2 2 0.0055 23 0 0 0 7.21E+06 5.33E+06 - - - 9.6081 0.9999 221125_WJC_METTL3_EV_vs_WT_F07.19635.19635.3 0.000324 22/72 K.TNGLPVQNGIDADVKDFSR.T "sp|Q14671|PUM1_HUMAN,tr|Q5T1Z8|Q5T1Z8_HUMAN,tr|H0YEH2|H0YEH2_HUMAN,tr|Q5T1Z4|Q5T1Z4_HUMAN" 4 2045.0178 2.28 105417 19635 3 2045.021304 682.6799 Pumilio homolog 1 OS=Homo sapiens OX=9606 GN=PUM1 PE=1 SV=3 4.43 3187 - 455708 - - - 1.7222 - 3.778 0.555 - 530.7 1 2 1 0.0035 19 0 0 0 1.48E+07 6.51E+06 - - - 7.9923 0.9998 221125_WJC_METTL3_EV_vs_WT_F07.19636.19636.3 0.000211 Dec-92 K.QHSSFGYGGLQGPASGLNAC[160.03]QYNS.- sp|P78337|PITX1_HUMAN 1 2499.0873 - 105418 19636 3 2499.090361 834.0364 Pituitary homeobox 1 OS=Homo sapiens OX=9606 GN=PITX1 PE=1 SV=2 6.73 3187.1 - 421409 - - - 1.2104 - 2.481 0.366 - 112.4 1 2 0 0.003 24 0 0 0 - - - - - 4.7302 0.9984 221125_WJC_METTL3_EV_vs_WT_F07.19637.19637.3 1.18E-06 12/108 L.TSFGTETSNSGTLPQSSAVGSAFTQDTR[166.11].S "sp|Q8ND56|LS14A_HUMAN,tr|A0A140TA76|A0A140TA76_HUMAN,tr|K7EMZ9|K7EMZ9_HUMAN" 3 2843.3085 0.97 105419 19637 3 2843.308299 948.7768 Protein LSM14 homolog A OS=Homo sapiens OX=9606 GN=LSM14A PE=1 SV=3 4.37 3187.2 - 347797 - - - -0.0689 - 2.706 0.6 - 90.7 1 1 0 -0.0002 28 0 0 0 7.23E+06 7.46E+06 - - - 7.5196 0.9942 221125_WJC_METTL3_EV_vs_WT_F07.19639.19639.4 9.02E-07 12/144 Y.GFMLQNEPLPHSC[160.03]NWVAASGPC[160.03]DKR.F sp|Q9H7S9|ZN703_HUMAN 1 2870.3051 1.92 105421 19639 4 2870.311412 718.5835 Zinc finger protein 703 OS=Homo sapiens OX=9606 GN=ZNF703 PE=1 SV=1 6.73 3187.5 - 275555 - - - 2.2085 - 2.761 0.527 - 55.1 1 1 0 0.0063 25 0 0 0 2.44E+06 1.27E+06 - - - 4.1343 1 221125_WJC_METTL3_EV_vs_WT_F07.19640.19640.3 1.48E-08 Oct-96 R.SLDNKGDTDGEDQVC[160.03]VSEISIVTNR.G sp|Q6ULP2|AFTIN_HUMAN 1 2750.2665 3 105422 19640 3 2750.261097 917.7628 Aftiphilin OS=Homo sapiens OX=9606 GN=AFTPH PE=1 SV=3 3.96 3187.6 - 249777 - - - -1.958 - 2.633 0.711 - 86.7 1 2 1 -0.0054 25 0 0 0 3.21E+06 1.07E+06 - - - 8.6928 0.9999 221125_WJC_METTL3_EV_vs_WT_F07.19644.19644.4 1.92E-05 13/120 K.TATQTGHTLLEDYQIVDNSQR.E sp|Q8N0X7|SPART_HUMAN 1 2389.151 1.61 105424 19644 4 2389.155046 598.295 Spartin OS=Homo sapiens OX=9606 GN=SPART PE=1 SV=1 4.53 3188.2 - 996326 - - - 1.701 - 2.771 0.415 - 101.8 1 2 0 0.0041 21 0 0 0 1.83E+07 1.14E+07 - - - 3.174 1 221125_WJC_METTL3_EV_vs_WT_F07.19646.19646.3 7.34E-09 25/80 K.TATQTGHTLLEDYQIVDNSQR[166.11].E sp|Q8N0X7|SPART_HUMAN 1 2399.1593 1.1 105426 19646 3 2399.162194 800.727 Spartin OS=Homo sapiens OX=9606 GN=SPART PE=1 SV=1 4.53 3188.4 - 5.76E+06 - - - 1.2263 - 4.153 0.604 - 536.3 1 2 0 0.0029 21 0 0 0 1.18E+08 1.08E+08 - - - 8.6868 0.9759 221125_WJC_METTL3_EV_vs_WT_F07.19647.19647.4 8.22E-06 14/120 K.TATQTGHTLLEDYQIVDNSQR[166.11].E sp|Q8N0X7|SPART_HUMAN 1 2399.1593 1.69 105427 19647 4 2400.169336 600.7971 Spartin OS=Homo sapiens OX=9606 GN=SPART PE=1 SV=1 4.53 3188.5 - 613971 - - - 421.0158 - 3.039 0.381 - 100.1 1 2 0 1.0101 21 0 0 0 1.90E+07 1.13E+07 - - - 2.6299 1 221125_WJC_METTL3_EV_vs_WT_F07.19648.19648.3 5.72E-09 19/76 K.K[136.11]PVVDC[160.03]VVSVPC[160.03]FYTDAER[166.11]R[166.11].S "sp|P34932|HSP74_HUMAN,tr|A0A087WTS8|A0A087WTS8_HUMAN,tr|A0A087WYC1|A0A087WYC1_HUMAN" 3 2424.1924 6.39 105428 19648 3 2424.194462 809.0714 Heat shock 70 kDa protein 4 OS=Homo sapiens OX=9606 GN=HSPA4 PE=1 SV=4 6.11 3188.6 - 459000 - - - 0.8395 - 4.029 0.636 - 450.3 1 2 0 0.002 20 0 0 0 4.84E+07 7.56E+06 - - - 9.0109 1 221125_WJC_METTL3_EV_vs_WT_F07.19649.19649.4 2.35E-07 22/114 R.DVHHEPVYPQPPFSYSDLSR[166.11].E "sp|Q14181|DPOA2_HUMAN,tr|A0A3B3ITS5|A0A3B3ITS5_HUMAN,tr|H0YDR7|H0YDR7_HUMAN" 3 2379.1159 0.86 105429 19649 4 2379.120397 595.7863 DNA polymerase alpha subunit B OS=Homo sapiens OX=9606 GN=POLA2 PE=1 SV=2 5.21 3188.7 - 437575 - - - 1.8776 - 4.47 0.598 - 609.2 1 2 0 0.0045 20 0 0 0 4.95E+06 5.74E+06 - - - 4.9304 1 221125_WJC_METTL3_EV_vs_WT_F07.19650.19650.3 3.76E-15 20/92 K.NGQHVASSPIPVVISQSEIGDASR.V "sp|P21333|FLNA_HUMAN,tr|Q60FE5|Q60FE5_HUMAN,tr|H0Y5C6|H0Y5C6_HUMAN" 3 2447.2405 1.4 105430 19650 3 2447.246336 816.7541 Filamin-A OS=Homo sapiens OX=9606 GN=FLNA PE=1 SV=4 5.32 3188.9 - 213607 - - - 2.399 - 3.976 0.718 - 420.9 1 2 0 0.0059 24 0 0 0 7.79E+06 5.56E+06 - - - 9.7492 0.967 221125_WJC_METTL3_EV_vs_WT_F07.19653.19653.3 1.54E-07 15/64 K.LHEEEIQELQAQIQEQH.V "sp|P08670|VIME_HUMAN,tr|B0YJC5|B0YJC5_HUMAN,tr|B0YJC4|B0YJC4_HUMAN" 3 2101.0076 - 105432 19653 3 2101.018669 701.3431 Vimentin OS=Homo sapiens OX=9606 GN=VIM PE=1 SV=4 4.31 3189.2 - 259713 - - - 5.2627 - 3.332 0.52 - 372.4 1 1 0 0.0111 17 0 0 0 - - - - - 7.375 1 221125_WJC_METTL3_EV_vs_WT_F07.19654.19654.4 1.67E-15 34/156 R.ATDK[136.11]DITGTLSNPEVFNYGVETHEAYK[136.11].Q "sp|P16083|NQO2_HUMAN,tr|Q5TD07|Q5TD07_HUMAN,tr|Q5TD05|Q5TD05_HUMAN" 3 3014.448 1.26 105433 19654 4 3014.452449 754.6193 Ribosyldihydronicotinamide dehydrogenase [quinone] OS=Homo sapiens OX=9606 GN=NQO2 PE=1 SV=5 4.5 3189.4 - 1.07E+06 - - - 1.4719 - 6.242 0.671 - 975.7 1 2 1 0.0044 27 0 0 0 3.44E+07 2.74E+07 - - - 5.6382 1 221125_WJC_METTL3_EV_vs_WT_F07.19656.19656.3 2.39E-11 23/88 K.TDEFQLHTNVNDGTEFGGSIYQK.V sp|P21796|VDAC1_HUMAN 1 2599.1827 1.37 105435 19656 3 2599.180708 867.4015 Voltage-dependent anion-selective channel protein 1 OS=Homo sapiens OX=9606 GN=VDAC1 PE=1 SV=2 4.31 3189.6 - 708753 - - - -0.7572 - 4.544 0.73 - 559.4 1 2 0 -0.002 23 0 0 0 1.84E+07 1.34E+07 - - - 10.2295 1 221125_WJC_METTL3_EV_vs_WT_F07.19657.19657.3 1.54E-14 20/88 K.TDEFQLHTNVNDGTEFGGSIYQK[136.11].V sp|P21796|VDAC1_HUMAN 1 2607.1969 1.36 105436 19657 3 2607.194906 870.0729 Voltage-dependent anion-selective channel protein 1 OS=Homo sapiens OX=9606 GN=VDAC1 PE=1 SV=2 4.31 3189.7 - 613146 - - - -0.7556 - 4.448 0.705 - 422.4 1 2 0 -0.002 23 0 0 0 1.81E+07 1.33E+07 - - - 9.9007 1 221125_WJC_METTL3_EV_vs_WT_F07.19658.19658.3 3.81E-12 26/92 K.DAPSLEEVEGHVADGSATEMGTTK.K "sp|Q15003|CND2_HUMAN,tr|C9J470|C9J470_HUMAN,tr|E9PHA2|E9PHA2_HUMAN" 3 2430.0857 1.58 105437 19658 3 2430.086897 811.0358 Condensin complex subunit 2 OS=Homo sapiens OX=9606 GN=NCAPH PE=1 SV=3 4.08 3189.9 - 454836 - - - 0.5074 - 4.25 0.675 - 791.2 1 2 0 0.0012 24 0 0 0 1.34E+07 8.51E+06 - - - 9.4259 1 221125_WJC_METTL3_EV_vs_WT_F07.19665.19665.4 3.00E-13 33/156 R.ATDKDITGTLSNPEVFNYGVETHEAYK.Q "sp|P16083|NQO2_HUMAN,tr|Q5TD07|Q5TD07_HUMAN,tr|Q5TD05|Q5TD05_HUMAN" 3 2998.4196 1.26 105442 19665 4 2998.430356 750.6122 Ribosyldihydronicotinamide dehydrogenase [quinone] OS=Homo sapiens OX=9606 GN=NQO2 PE=1 SV=5 4.5 3190.7 - 2.14E+06 - - - 3.5832 - 5.592 0.641 - 714.1 1 2 1 0.0107 27 0 0 0 3.44E+07 2.74E+07 - - - 5.3409 1 221125_WJC_METTL3_EV_vs_WT_F07.19669.19669.3 1.97E-11 21/88 R.SYIDRDSEYLLQENEPDGTLDQK.L "sp|Q9H2U1|DHX36_HUMAN,tr|E7EWK3|E7EWK3_HUMAN" 2 2727.2511 0.97 105446 19669 3 2727.262293 910.091 ATP-dependent DNA\RNA helicase DHX36 OS=Homo sapiens OX=9606 GN=DHX36 PE=1 SV=2 3.9 3191.3 - 495292 - - - 4.0862 - 3.876 0.655 - 443.5 1 2 1 0.0111 23 0 0 0 8.79E+06 9.03E+06 - - - 9.0178 0.9997 221125_WJC_METTL3_EV_vs_WT_F07.19670.19670.4 2.23E-08 19/150 R.EEIHKDLLVTGAYEISDQSGGAGGLR.S "sp|P49755|TMEDA_HUMAN,tr|G3V2K7|G3V2K7_HUMAN" 2 2714.3511 1.45 105447 19670 4 2714.360191 679.5951 Transmembrane emp24 domain-containing protein 10 OS=Homo sapiens OX=9606 GN=TMED10 PE=1 SV=2 4.5 3191.4 - 463253 - - - 3.3352 - 3.513 0.544 - 181.9 1 2 1 0.0091 26 0 0 0 2.78E+07 1.91E+07 - - - 4.3548 1 221125_WJC_METTL3_EV_vs_WT_F07.19672.19672.4 1.13E-07 15/114 R.DVHHEPVYPQPPFSYSDLSR.E "sp|Q14181|DPOA2_HUMAN,tr|A0A3B3ITS5|A0A3B3ITS5_HUMAN,tr|H0YDR7|H0YDR7_HUMAN" 3 2369.1077 0.83 105449 19672 4 2369.104621 593.2842 DNA polymerase alpha subunit B OS=Homo sapiens OX=9606 GN=POLA2 PE=1 SV=2 5.21 3191.7 - 258937 - - - -1.2828 - 3.132 0.556 - 167.4 1 2 0 -0.003 20 0 0 0 4.95E+06 6.00E+06 - - - 4.4463 0.9999 221125_WJC_METTL3_EV_vs_WT_F07.19677.19677.4 8.61E-07 21/150 R.EEIHK[136.11]DLLVTGAYEISDQSGGAGGLR[166.11].S "sp|P49755|TMEDA_HUMAN,tr|G3V2K7|G3V2K7_HUMAN" 2 2732.3736 1.68 105452 19677 4 2732.378281 684.1007 Transmembrane emp24 domain-containing protein 10 OS=Homo sapiens OX=9606 GN=TMED10 PE=1 SV=2 4.5 3192.3 - 844658 - - - 1.7102 - 3.713 0.531 - 196.8 1 2 1 0.0047 26 0 0 0 3.26E+07 1.94E+07 - - - 4.2603 1 221125_WJC_METTL3_EV_vs_WT_F07.19678.19678.3 7.34E-12 26/92 K.DAPSLEEVEGHVADGSATEMGTTK[136.11].K "sp|Q15003|CND2_HUMAN,tr|C9J470|C9J470_HUMAN,tr|E9PHA2|E9PHA2_HUMAN" 3 2438.0999 1.64 105453 19678 3 2438.096348 813.7072 Condensin complex subunit 2 OS=Homo sapiens OX=9606 GN=NCAPH PE=1 SV=3 4.08 3192.5 - 674488 - - - -1.4421 - 4.237 0.651 - 795.1 1 2 0 -0.0035 24 0 0 0 1.39E+07 8.51E+06 - - - 9.1505 1 221125_WJC_METTL3_EV_vs_WT_F07.19679.19679.3 1.83E-07 22/88 R.SYIDR[166.11]DSEYLLQENEPDGTLDQK[136.11].L "sp|Q9H2U1|DHX36_HUMAN,tr|E7EWK3|E7EWK3_HUMAN" 2 2745.2736 0.9 105454 19679 3 2745.272935 916.0985 ATP-dependent DNA\RNA helicase DHX36 OS=Homo sapiens OX=9606 GN=DHX36 PE=1 SV=2 3.9 3192.6 - 501186 - - - -0.2492 - 4.295 0.686 - 520.7 1 2 1 -0.0007 23 0 0 0 8.79E+06 9.81E+06 - - - 9.6071 1 221125_WJC_METTL3_EV_vs_WT_F07.19680.19680.3 5.19E-11 24/92 K.NGQHVASSPIPVVISQSEIGDASR[166.11].V "sp|P21333|FLNA_HUMAN,tr|Q60FE5|Q60FE5_HUMAN,tr|H0Y5C6|H0Y5C6_HUMAN" 3 2457.2487 1.37 105455 19680 3 2457.255322 820.0902 Filamin-A OS=Homo sapiens OX=9606 GN=FLNA PE=1 SV=4 5.32 3192.7 - 483799 - - - 2.6806 - 4.477 0.689 - 789 1 2 0 0.0066 24 0 0 0 7.62E+06 5.56E+06 - - - 9.7013 1 221125_WJC_METTL3_EV_vs_WT_F07.19688.19688.3 3.68E-14 22/128 S.SLNSYGAQGSSLASYGNQPSSYGAQAASSYGVR.A sp|Q96PK6|RBM14_HUMAN 1 3284.497 2.01 105461 19688 3 3284.501983 1095.8396 RNA-binding protein 14 OS=Homo sapiens OX=9606 GN=RBM14 PE=1 SV=2 8.15 3193.7 - 970286 - - - 1.5089 - 4.537 0.699 - 340 1 1 0 0.005 33 0 0 0 1.01E+07 5.03E+06 - - - 9.811 1 221125_WJC_METTL3_EV_vs_WT_F07.19689.19689.4 8.10E-08 20/120 K.GPEEK[136.11]K[136.11]DC[160.03]EVVMMIGLPGAGK[136.11].T "sp|Q00839|HNRPU_HUMAN,tr|A0A1W2PQL0|A0A1W2PQL0_HUMAN,tr|A0A1W2PPL4|A0A1W2PPL4_HUMAN,tr|A0A1W2PQ74|A0A1W2PQ74_HUMAN,tr|Q5RI18|Q5RI18_HUMAN,tr|A0A1W2PP35|A0A1W2PP35_HUMAN,tr|A0A1W2PPS1|A0A1W2PPS1_HUMAN,tr|A0A1W2PRZ7|A0A1W2PRZ7_HUMAN,tr|A0A1W2PPH7|A0A1W2PPH7_HUMAN,tr|A0A1W2PQD4|A0A1W2PQD4_HUMAN,tr|A0A1W2PP34|A0A1W2PP34_HUMAN,tr|A0A1X7SBS1|A0A1X7SBS1_HUMAN" 12 2268.1378 0.99 105462 19689 4 2268.14198 568.0417 Heterogeneous nuclear ribonucleoprotein U OS=Homo sapiens OX=9606 GN=HNRNPU PE=1 SV=6 4.87 3193.8 - 1.10E+06 - - - 1.8222 - 3.352 0.638 - 235.2 1 2 1 0.0041 21 0 0 0 2.63E+07 2.65E+07 - - - 5.1779 1 221125_WJC_METTL3_EV_vs_WT_F07.19690.19690.3 1.24E-11 17/128 S.SLNSYGAQGSSLASYGNQPSSYGAQAASSYGVR[166.11].A sp|Q96PK6|RBM14_HUMAN 1 3294.5053 2.01 105463 19690 3 3294.507598 1099.1757 RNA-binding protein 14 OS=Homo sapiens OX=9606 GN=RBM14 PE=1 SV=2 8.15 3193.9 - 489930 - - - 0.6984 - 3.683 0.655 - 167.8 1 1 0 0.0023 33 0 0 0 1.01E+07 5.03E+06 - - - 8.8414 1 221125_WJC_METTL3_EV_vs_WT_F07.19692.19692.3 3.91E-09 16/104 R.ATDKDITGTLSNPEVFNYGVETHEAYK.Q "sp|P16083|NQO2_HUMAN,tr|Q5TD07|Q5TD07_HUMAN,tr|Q5TD05|Q5TD05_HUMAN" 3 2998.4196 1.68 105465 19692 3 2998.425936 1000.4805 Ribosyldihydronicotinamide dehydrogenase [quinone] OS=Homo sapiens OX=9606 GN=NQO2 PE=1 SV=5 4.5 3194.2 - 413708 - - - 2.1091 - 3.467 0.669 - 223.5 1 2 1 0.0063 27 0 0 0 4.05E+06 2.41E+06 - - - 8.8573 0.9991 221125_WJC_METTL3_EV_vs_WT_F07.19693.19693.4 1.92E-06 16/126 R.TSNTVYLDYR[166.11]PHK[136.11]PGLYLELTR[166.11].K sp|Q5SRI9|MANEA_HUMAN 1 2663.4066 0.63 105466 19693 4 2663.40925 666.8589 "Glycoprotein endo-alpha-1,2-mannosidase OS=Homo sapiens OX=9606 GN=MANEA PE=1 SV=1" 8.13 3194.3 - 403699 - - - 1.0036 - 3.116 0.288 - 104.7 1 2 0 0.0027 22 0 0 0 6.13E+06 9.77E+06 - - - 2.1039 1 221125_WJC_METTL3_EV_vs_WT_F07.19697.19697.4 1.13E-11 24/126 Q.IQEQHVQIDVDVSKPDLTAALR.D "sp|P08670|VIME_HUMAN,tr|B0YJC5|B0YJC5_HUMAN,tr|B0YJC4|B0YJC4_HUMAN" 3 2474.3129 2.76 105468 19697 4 2474.319452 619.5855 Vimentin OS=Homo sapiens OX=9606 GN=VIM PE=1 SV=4 4.66 3194.8 - 809502 - - - 2.6472 - 4.112 0.66 - 269.1 1 1 0 0.0066 22 0 0 0 3.57E+07 1.29E+07 - - - 5.4315 0.9999 221125_WJC_METTL3_EV_vs_WT_F07.19703.19703.4 2.30E-07 16/108 K.VTEGLVDVILYHQPDDKKK.N "sp|O43390|HNRPR_HUMAN,tr|B4DT28|B4DT28_HUMAN,tr|A0A6Q8PHG0|A0A6Q8PHG0_HUMAN,tr|A0A6Q8PH31|A0A6Q8PH31_HUMAN,tr|A0A6Q8PEX7|A0A6Q8PEX7_HUMAN" 5 2196.179 1.48 105473 19703 4 2196.182839 550.052 Heterogeneous nuclear ribonucleoprotein R OS=Homo sapiens OX=9606 GN=HNRNPR PE=1 SV=1 5.43 3195.6 - 517786 - - - 1.7326 - 3.103 0.529 - 119.6 1 2 1 0.0038 19 0 0 0 7.60E+06 5.12E+06 - - - 4.2124 0.9926 221125_WJC_METTL3_EV_vs_WT_F07.19706.19706.4 4.81E-08 16/156 Q.QLPHGLGGIGMGLGPGGQPIDANHLNK.G "sp|P52272|HNRPM_HUMAN,tr|M0R019|M0R019_HUMAN,tr|M0R0N3|M0R0N3_HUMAN,tr|M0QYL3|M0QYL3_HUMAN,tr|A0A087X0X3|A0A087X0X3_HUMAN,tr|M0QZM1|M0QZM1_HUMAN" 6 2647.3653 1.76 105476 19706 4 2647.372107 662.8486 Heterogeneous nuclear ribonucleoprotein M OS=Homo sapiens OX=9606 GN=HNRNPM PE=1 SV=3 6.92 3195.9 - 297730 - - - 2.5754 - 3.331 0.521 - 112.7 1 1 0 0.0068 27 0 0 0 7.24E+06 4.11E+06 - - - 4.1354 1 221125_WJC_METTL3_EV_vs_WT_F07.19714.19714.3 9.10E-16 26/100 R.EEIHK[136.11]DLLVTGAYEISDQSGGAGGLR[166.11].S "sp|P49755|TMEDA_HUMAN,tr|G3V2K7|G3V2K7_HUMAN" 2 2732.3736 1.27 105482 19714 3 2732.370218 911.7985 Transmembrane emp24 domain-containing protein 10 OS=Homo sapiens OX=9606 GN=TMED10 PE=1 SV=2 4.5 3197 - 421371 - - - -1.2407 - 4.639 0.578 - 549.1 1 2 1 -0.0034 26 0 0 0 5.90E+06 4.66E+06 - - - 8.5135 1 221125_WJC_METTL3_EV_vs_WT_F07.19720.19720.4 2.37E-10 27/192 R.VLGKPEPAAQPVPESLPGEPEILPQAPANAHLK.D "sp|Q9NY61|AATF_HUMAN,tr|A0A7P0T868|A0A7P0T868_HUMAN,tr|A0A7P0TAR0|A0A7P0TAR0_HUMAN,tr|A0A087WWS8|A0A087WWS8_HUMAN,tr|A0A7P0TBI0|A0A7P0TBI0_HUMAN,tr|A0A7P0Z4P2|A0A7P0Z4P2_HUMAN,tr|A0A7P0Z4N2|A0A7P0Z4N2_HUMAN,tr|A0A087WTH8|A0A087WTH8_HUMAN,tr|A0A7P0Z434|A0A7P0Z434_HUMAN" 9 3393.8296 1.94 105486 19720 4 3393.833999 849.4647 Protein AATF OS=Homo sapiens OX=9606 GN=AATF PE=1 SV=1 4.91 3197.8 - 1.42E+06 - - - 1.2838 - 4.274 0.578 - 212.9 1 2 0 0.0044 33 0 0 0 1.51E+07 7.78E+06 - - - 4.6915 0.9975 221125_WJC_METTL3_EV_vs_WT_F07.19724.19724.4 1.34E-07 24/126 Q.IQEQHVQIDVDVSK[136.11]PDLTAALR[166.11].D "sp|P08670|VIME_HUMAN,tr|B0YJC5|B0YJC5_HUMAN,tr|B0YJC4|B0YJC4_HUMAN" 3 2492.3354 2.79 105490 19724 4 2492.337624 624.0911 Vimentin OS=Homo sapiens OX=9606 GN=VIM PE=1 SV=4 4.66 3198.2 - 1.00E+06 - - - 0.9036 - 3.488 0.545 - 256.3 1 1 0 0.0023 22 0 0 0 3.57E+07 1.28E+07 - - - 4.3778 1 221125_WJC_METTL3_EV_vs_WT_F07.19726.19726.4 3.51E-12 29/168 R.PQQLPHGLGGIGMGLGPGGQPIDANHLNK.G "sp|P52272|HNRPM_HUMAN,tr|M0R019|M0R019_HUMAN,tr|M0R0N3|M0R0N3_HUMAN,tr|M0QYL3|M0QYL3_HUMAN,tr|A0A087X0X3|A0A087X0X3_HUMAN,tr|M0QZM1|M0QZM1_HUMAN" 6 2872.4766 2.03 105492 19726 4 2872.480837 719.1264 Heterogeneous nuclear ribonucleoprotein M OS=Homo sapiens OX=9606 GN=HNRNPM PE=1 SV=3 7.33 3198.5 - 817829 - - - 1.4646 - 5.418 0.659 - 422.5 1 1 0 0.0042 29 0 0 0 4.05E+06 1.99E+06 - - - 5.4815 1 221125_WJC_METTL3_EV_vs_WT_F07.19728.19728.4 6.96E-10 27/168 N.IVASNSLPPATIAPPKPASWADIASKPAK.Q sp|Q9Y5A9|YTHD2_HUMAN 1 2897.6015 2.6 105494 19728 4 2897.610323 725.4076 YTH domain-containing family protein 2 OS=Homo sapiens OX=9606 GN=YTHDF2 PE=1 SV=2 9.7 3198.7 - 634629 - - - 3.0518 - 4.546 0.624 - 450.9 1 1 0 0.0088 29 0 0 0 8.74E+06 3.36E+06 - - - 5.1215 0.9945 221125_WJC_METTL3_EV_vs_WT_F07.19729.19729.4 7.78E-07 23/156 Q.QLPHGLGGIGMGLGPGGQPIDANHLNK[136.11].G "sp|P52272|HNRPM_HUMAN,tr|M0R019|M0R019_HUMAN,tr|M0R0N3|M0R0N3_HUMAN,tr|M0QYL3|M0QYL3_HUMAN,tr|A0A087X0X3|A0A087X0X3_HUMAN,tr|M0QZM1|M0QZM1_HUMAN" 6 2655.3795 1.76 105495 19729 4 2655.38459 664.8521 Heterogeneous nuclear ribonucleoprotein M OS=Homo sapiens OX=9606 GN=HNRNPM PE=1 SV=3 6.92 3198.9 - 613477 - - - 1.921 - 4.05 0.5 - 249.7 1 1 0 0.0051 27 0 0 0 7.24E+06 4.11E+06 - - - 4.0142 1 221125_WJC_METTL3_EV_vs_WT_F07.19732.19732.3 1.17E-10 18/132 A.SSLNSYGAQGSSLASYGNQPSSYGAQAASSYGVR[166.11].A sp|Q96PK6|RBM14_HUMAN 1 3381.5373 2.93 105498 19732 3 3381.535595 1128.1864 RNA-binding protein 14 OS=Homo sapiens OX=9606 GN=RBM14 PE=1 SV=2 8.15 3199.3 - 300632 - - - -0.5119 - 3.894 0.709 - 197 1 1 0 -0.0017 34 0 0 0 5.95E+06 2.03E+06 - - - 9.5717 0.9984 221125_WJC_METTL3_EV_vs_WT_F07.19733.19733.2 0.134 16-Jul R.LLLPGELAK[136.11].H "sp|Q8N257|H2B3B_HUMAN,sp|A0A2R8Y619|H2BE1_HUMAN,sp|P33778|H2B1B_HUMAN,sp|Q96A08|H2B1A_HUMAN,sp|Q5QNW6|H2B2F_HUMAN,sp|P58876|H2B1D_HUMAN,sp|Q99880|H2B1L_HUMAN,sp|P62807|H2B1C_HUMAN,sp|Q99877|H2B1N_HUMAN,sp|P57053|H2BFS_HUMAN,sp|P23527|H2B1O_HUMAN,sp|O60814|H2B1K_HUMAN,sp|Q93079|H2B1H_HUMAN,sp|Q99879|H2B1M_HUMAN,sp|Q16778|H2B2E_HUMAN,sp|P06899|H2B1J_HUMAN,tr|U3KQK0|U3KQK0_HUMAN" 17 960.6099 1.5 105499 19733 2 960.61047 481.3122 Histone H2B type 3-B OS=Homo sapiens OX=9606 GN=H2BU1 PE=1 SV=3 6 3199.4 - 271669 - - - 0.5746 - 1.444 0.266 - 117 1 2 0 0.0006 9 0 0 0 8.46E+06 5.66E+06 - - - 2.0685 1 221125_WJC_METTL3_EV_vs_WT_F07.19738.19738.3 1.47E-15 26/132 A.SSLNSYGAQGSSLASYGNQPSSYGAQAASSYGVR.A sp|Q96PK6|RBM14_HUMAN 1 3371.5291 2.93 105502 19738 3 3371.532384 1124.8503 RNA-binding protein 14 OS=Homo sapiens OX=9606 GN=RBM14 PE=1 SV=2 8.15 3200.1 - 608226 - - - 0.9871 - 3.885 0.774 - 453.2 1 1 0 0.0033 34 0 0 0 5.95E+06 2.03E+06 - - - 10.2907 1 221125_WJC_METTL3_EV_vs_WT_F07.19740.19740.3 2.79E-11 20/84 L.SEVQQAVSQGSSDSQILDLSNR.F "sp|P09874|PARP1_HUMAN,tr|A0A7I2V3E1|A0A7I2V3E1_HUMAN" 2 2347.1252 1.31 105504 19740 3 2347.131697 783.3823 Poly [ADP-ribose] polymerase 1 OS=Homo sapiens OX=9606 GN=PARP1 PE=1 SV=4 4.03 3200.2 - 1.10E+06 - - - 2.7847 - 3.809 0.646 - 507.9 1 1 0 0.0065 22 0 0 0 1.19E+07 9.08E+06 - - - 8.9111 0.9843 221125_WJC_METTL3_EV_vs_WT_F07.19742.19742.4 9.49E-07 14/162 V.VSSDFNSDTHSSTFDAGAGIALNDHFVK.L "sp|P04406|G3P_HUMAN,tr|E7EUT5|E7EUT5_HUMAN" 2 2938.3369 1.45 105506 19742 4 2938.346376 735.5915 Glyceraldehyde-3-phosphate dehydrogenase OS=Homo sapiens OX=9606 GN=GAPDH PE=1 SV=3 4.54 3200.5 - 606667 - - - 3.2096 - 2.633 0.5 - 85.4 1 1 0 0.0094 28 0 0 0 4.21E+06 2.90E+06 - - - 3.876 1 221125_WJC_METTL3_EV_vs_WT_F07.19744.19744.3 9.09E-13 29/108 R.AAASLAAVSGTAAASLGSAQPTDLGAHK.R sp|Q7Z5L9|I2BP2_HUMAN 1 2493.2823 1.66 105508 19744 3 2493.292875 832.1014 Interferon regulatory factor 2-binding protein 2 OS=Homo sapiens OX=9606 GN=IRF2BP2 PE=1 SV=2 6.79 3200.7 - 443885 - - - 4.2294 - 4.756 0.653 - 671.6 1 2 0 0.0105 28 0 0 0 6.55E+07 3.94E+07 - - - 9.405 1 221125_WJC_METTL3_EV_vs_WT_F07.19752.19752.3 2.07E-14 24/80 K.SVSPQNSDSSGFADVNGWHLR.F "sp|Q9UKB3|DJC12_HUMAN,tr|S4R3E2|S4R3E2_HUMAN" 2 2259.0305 0.68 105514 19752 3 2259.03047 754.0174 DnaJ homolog subfamily C member 12 OS=Homo sapiens OX=9606 GN=DNAJC12 PE=1 SV=1 5.19 3201.8 - 913391 - - - -0.0009 - 4.269 0.738 - 668.2 1 2 0 0 21 0 0 0 1.28E+07 1.89E+07 - - - 10.2476 0.9844 221125_WJC_METTL3_EV_vs_WT_F07.19753.19753.2 9.21 16-Jul R.LLLPGELAK.H "sp|Q8N257|H2B3B_HUMAN,sp|A0A2R8Y619|H2BE1_HUMAN,sp|P33778|H2B1B_HUMAN,sp|Q96A08|H2B1A_HUMAN,sp|Q5QNW6|H2B2F_HUMAN,sp|P58876|H2B1D_HUMAN,sp|Q99880|H2B1L_HUMAN,sp|P62807|H2B1C_HUMAN,sp|Q99877|H2B1N_HUMAN,sp|P57053|H2BFS_HUMAN,sp|P23527|H2B1O_HUMAN,sp|O60814|H2B1K_HUMAN,sp|Q93079|H2B1H_HUMAN,sp|Q99879|H2B1M_HUMAN,sp|Q16778|H2B2E_HUMAN,sp|P06899|H2B1J_HUMAN,tr|U3KQK0|U3KQK0_HUMAN" 17 952.5957 1.5 105515 19753 2 952.596958 477.3051 Histone H2B type 3-B OS=Homo sapiens OX=9606 GN=H2BU1 PE=1 SV=3 6 3202 - 479481 - - - 1.3017 - 1.223 0.133 - 132.7 1 2 0 0.0012 9 0 0 0 8.46E+06 5.66E+06 - - - 0.6053 1 221125_WJC_METTL3_EV_vs_WT_F07.19755.19755.3 2.17E-11 17/108 K.QHSSFGYASVQNPASNLSAC[160.03]QYAVDRPV.- sp|Q99697|PITX2_HUMAN 1 3052.4097 3.67 105517 19755 3 3052.410418 1018.4772 Pituitary homeobox 2 OS=Homo sapiens OX=9606 GN=PITX2 PE=1 SV=2 6.73 3202.2 - 354150 - - - 0.2244 - 3.61 0.714 - 203.4 1 2 0 0.0007 28 0 0 0 4.04E+06 1.10E+06 - - - 9.4535 1 221125_WJC_METTL3_EV_vs_WT_F07.19756.19756.3 2.02E-11 18/84 Q.IQEQHVQIDVDVSKPDLTAALR.D "sp|P08670|VIME_HUMAN,tr|B0YJC5|B0YJC5_HUMAN,tr|B0YJC4|B0YJC4_HUMAN" 3 2474.3129 15.49 105518 19756 3 2474.312766 825.7782 Vimentin OS=Homo sapiens OX=9606 GN=VIM PE=1 SV=4 4.66 3202.4 - 297786 - - - -0.055 - 3.959 0.646 - 204.3 1 1 0 -0.0001 22 0 0 0 2.60E+06 1.68E+05 - - - 9.0045 0.9718 221125_WJC_METTL3_EV_vs_WT_F07.19762.19762.4 0.000405 12/168 N.IVASNSLPPATIAPPK[136.11]PASWADIASK[136.11]PAK[136.11].Q sp|Q9Y5A9|YTHD2_HUMAN 1 2921.6441 2.55 105522 19762 4 2921.649436 731.4183 YTH domain-containing family protein 2 OS=Homo sapiens OX=9606 GN=YTHDF2 PE=1 SV=2 9.7 3203.1 - 256785 - - - 1.8336 - 2.556 0.388 - 69.3 1 1 0 0.0054 29 0 0 0 8.56E+06 3.36E+06 - - - 2.8909 1 221125_WJC_METTL3_EV_vs_WT_F07.19768.19768.4 1.69E-06 23/162 R.AAASLAAVSGTAAASLGSAQPTDLGAHK.R sp|Q7Z5L9|I2BP2_HUMAN 1 2493.2823 1.41 105526 19768 4 2493.284952 624.3279 Interferon regulatory factor 2-binding protein 2 OS=Homo sapiens OX=9606 GN=IRF2BP2 PE=1 SV=2 6.79 3203.9 - 3.19E+06 - - - 1.0516 - 3.725 0.499 - 208 1 2 0 0.0026 28 0 0 0 3.29E+07 2.34E+07 - - - 3.9769 1 221125_WJC_METTL3_EV_vs_WT_F07.19772.19772.4 5.93E-09 19/144 R.ANPTTGSVEWLEEDEHYDYHQEIAR[166.11].S "sp|Q9NVM4|ANM7_HUMAN,tr|H3BSS9|H3BSS9_HUMAN,tr|H3BRQ9|H3BRQ9_HUMAN,tr|H3BPZ8|H3BPZ8_HUMAN,tr|A0A6Q8PFP4|A0A6Q8PFP4_HUMAN,tr|H3BNC0|H3BNC0_HUMAN,tr|H3BRD3|H3BRD3_HUMAN,tr|H3BTY1|H3BTY1_HUMAN" 8 2998.3245 0.05 105530 19772 4 2998.322552 750.5884 Protein arginine N-methyltransferase 7 OS=Homo sapiens OX=9606 GN=PRMT7 PE=1 SV=1 4.24 3204.5 - 339031 - - - -0.6427 - 3.405 0.628 - 266.5 1 2 0 -0.0019 25 0 0 0 1.67E+05 3.40E+06 - - - 5.0814 0.9573 221125_WJC_METTL3_EV_vs_WT_F07.19773.19773.4 0.139 11/120 K.EYRPHLVDQGAMLLNVSGHVK.E "sp|P22735|TGM1_HUMAN,tr|H0YMQ8|H0YMQ8_HUMAN" 2 2362.2216 19.73 105531 19773 4 2362.225463 591.5627 Protein-glutamine gamma-glutamyltransferase K OS=Homo sapiens OX=9606 GN=TGM1 PE=1 SV=4 7.01 3204.6 - 296268 - - - 1.6421 - 2.035 0.148 - 62.8 1 2 0 0.0039 21 0 0 0 4.10E+06 2.08E+05 - - - 0.748 0.9998 221125_WJC_METTL3_EV_vs_WT_F07.19776.19776.3 0.000391 Oct-68 R.GK[136.11]PPPLLPSVLGPAGGDR[166.11].E "sp|Q8IY67|RAVR1_HUMAN,tr|E9PAU2|E9PAU2_HUMAN,tr|A0A087WZ13|A0A087WZ13_HUMAN" 3 1744.9955 0.96 105534 19776 3 1744.994122 582.6724 Ribonucleoprotein PTB-binding 1 OS=Homo sapiens OX=9606 GN=RAVER1 PE=1 SV=1 8.75 3205 - 208736 - - - -0.7748 - 1.86 0.401 - 74 1 2 0 -0.0014 18 0 0 0 2.34E+06 2.44E+06 - - - 4.5557 0.9999 221125_WJC_METTL3_EV_vs_WT_F07.19782.19782.4 9.90E-09 17/132 K.FKPVIGTWDC[160.03]DTC[160.03]LVQNKPEAIK.C sp|P49790|NU153_HUMAN 1 2718.3509 1.21 105538 19782 4 2718.362647 680.595 Nuclear pore complex protein Nup153 OS=Homo sapiens OX=9606 GN=NUP153 PE=1 SV=2 6.11 3205.8 - 873977 - - - 4.3052 - 3.535 0.589 - 170.1 1 2 0 0.0117 23 0 0 0 1.30E+07 1.07E+07 - - - 4.7585 0.9999 221125_WJC_METTL3_EV_vs_WT_F07.19783.19783.4 2.26E-07 21/144 R.LSIPSLTC[160.03]NPDKTDGPVFHSNTLER.K "sp|Q4VCS5|AMOT_HUMAN,tr|E7ERM3|E7ERM3_HUMAN" 2 2797.3705 1.8 105539 19783 4 2797.369441 700.3499 Angiomotin OS=Homo sapiens OX=9606 GN=AMOT PE=1 SV=1 5.38 3205.9 - 670249 - - - -0.3764 - 4.093 0.573 - 317 1 2 1 -0.0011 25 0 0 0 2.69E+07 1.50E+07 - - - 4.6614 0.9978 221125_WJC_METTL3_EV_vs_WT_F07.19785.19785.3 1.92E-06 Dec-52 R.HFDFDLEDFK[136.11]GNSK[136.11].V "sp|Q6KC79|NIPBL_HUMAN,tr|A0A590UJS4|A0A590UJS4_HUMAN" 2 1713.7969 0.54 105541 19785 3 1713.800232 572.2729 Nipped-B-like protein OS=Homo sapiens OX=9606 GN=NIPBL PE=1 SV=2 4.66 3206.2 - 378716 - - - 1.915 - 2.35 0.318 - 105.1 1 2 1 0.0033 14 0 0 0 7.55E+06 1.40E+07 - - - 4.3551 1 221125_WJC_METTL3_EV_vs_WT_F07.19792.19792.3 1.86E-10 27/108 R.AAASLAAVSGTAAASLGSAQPTDLGAHK[136.11].R sp|Q7Z5L9|I2BP2_HUMAN 1 2501.2965 1.66 105545 19792 3 2501.292385 834.7728 Interferon regulatory factor 2-binding protein 2 OS=Homo sapiens OX=9606 GN=IRF2BP2 PE=1 SV=2 6.79 3207.1 - 2.66E+06 - - - -1.6571 - 4.723 0.541 - 553.8 1 2 0 -0.0041 28 0 0 0 6.55E+07 3.94E+07 - - - 8.1421 0.9946 221125_WJC_METTL3_EV_vs_WT_F07.19793.19793.4 1.75E-05 21/162 R.AAASLAAVSGTAAASLGSAQPTDLGAHK[136.11].R sp|Q7Z5L9|I2BP2_HUMAN 1 2501.2965 1.41 105546 19793 4 2502.294729 626.3314 Interferon regulatory factor 2-binding protein 2 OS=Homo sapiens OX=9606 GN=IRF2BP2 PE=1 SV=2 6.79 3207.2 - 1.49E+06 - - - 399.0726 - 4.088 0.431 - 157.3 1 2 0 0.9982 28 0 0 0 3.29E+07 2.34E+07 - - - 3.1381 1 221125_WJC_METTL3_EV_vs_WT_F07.19797.19797.4 1.01E-10 23/156 K.IGEEQSAEDAEDGPPELLFIHGGHTAK.L "sp|Q16576|RBBP7_HUMAN,tr|Q5JNZ6|Q5JNZ6_HUMAN,tr|E9PC52|E9PC52_HUMAN" 3 2846.3359 1.47 105548 19797 4 2846.329234 712.5912 Histone-binding protein RBBP7 OS=Homo sapiens OX=9606 GN=RBBP7 PE=1 SV=1 4.24 3207.7 - 849943 - - - -2.3356 - 4.325 0.646 - 247.4 1 2 0 -0.0066 27 0 0 0 6.24E+08 4.23E+08 - - - 5.3051 1 221125_WJC_METTL3_EV_vs_WT_F07.19813.19813.3 5.80E-08 17/72 R.K[136.11]EGGGGISC[160.03]VLQDGC[160.03]VFEK[136.11].A sp|P36551|HEM6_HUMAN 1 2054.9736 1.09 105557 19813 3 2054.967739 685.9985 "Oxygen-dependent coproporphyrinogen-III oxidase, mitochondrial OS=Homo sapiens OX=9606 GN=CPOX PE=1 SV=3" 4.68 3209.8 - 1.28E+06 - - - -2.8579 - 3.478 0.576 - 414.2 1 2 0 -0.0059 19 0 0 0 3.81E+07 3.48E+07 - - - 8.0225 1 221125_WJC_METTL3_EV_vs_WT_F07.19814.19814.4 1.94E-18 30/156 K.IGEEQSAEDAEDGPPELLFIHGGHTAK[136.11].L "sp|Q16576|RBBP7_HUMAN,tr|Q5JNZ6|Q5JNZ6_HUMAN,tr|E9PC52|E9PC52_HUMAN" 3 2854.3501 1.48 105558 19814 4 2854.335083 714.5948 Histone-binding protein RBBP7 OS=Homo sapiens OX=9606 GN=RBBP7 PE=1 SV=1 4.24 3209.9 - 1.56E+06 - - - -5.2548 - 4.942 0.682 - 645.4 1 2 0 -0.015 27 0 0 0 6.24E+08 4.23E+08 - - - 5.6579 1 221125_WJC_METTL3_EV_vs_WT_F07.19818.19818.3 4.17E-09 23/72 R.KEGGGGISC[160.03]VLQDGC[160.03]VFEK.A sp|P36551|HEM6_HUMAN 1 2038.9452 1.09 105559 19818 3 2038.946738 680.6557 "Oxygen-dependent coproporphyrinogen-III oxidase, mitochondrial OS=Homo sapiens OX=9606 GN=CPOX PE=1 SV=3" 4.68 3210.4 - 1.51E+06 - - - 0.7484 - 3.882 0.58 - 908.4 1 2 0 0.0015 19 0 0 0 3.81E+07 3.48E+07 - - - 8.3383 0.9999 221125_WJC_METTL3_EV_vs_WT_F07.19820.19820.3 1.59E-10 20/72 K.LR[166.11]ENSASQISQLEQQLSAK[136.11].N "sp|Q13948|CASP_HUMAN,sp|P39880|CUX1_HUMAN,tr|A0A2R8Y852|A0A2R8Y852_HUMAN,tr|A0A2R8YDI1|A0A2R8YDI1_HUMAN" 4 2147.1301 1.31 105560 19820 3 2147.124602 716.7173 Protein CASP OS=Homo sapiens OX=9606 GN=CUX1 PE=1 SV=2 6.14 3210.7 - 1.02E+06 - - - -2.5746 - 3.895 0.584 - 479.5 1 2 1 -0.0055 19 0 0 0 2.61E+08 1.99E+08 - - - 8.39 1 221125_WJC_METTL3_EV_vs_WT_F07.19824.19824.3 7.92E-11 19/64 R.IINEPTAAAIAYGLDKK.G "sp|P54652|HSP72_HUMAN,sp|P11142|HSP7C_HUMAN,tr|E9PKE3|E9PKE3_HUMAN,tr|E9PN89|E9PN89_HUMAN,tr|E9PI65|E9PI65_HUMAN" 5 1786.9829 0.38 105562 19824 3 1786.983089 596.6682 Heat shock-related 70 kDa protein 2 OS=Homo sapiens OX=9606 GN=HSPA2 PE=1 SV=1 6.07 3211.2 - 859275 - - - 0.1058 - 3.738 0.513 - 436.6 1 2 0 0.0002 17 0 0 0 3.09E+07 8.18E+07 - - - 7.5904 0.9933 221125_WJC_METTL3_EV_vs_WT_F07.19826.19826.4 3.48E-05 14/156 S.SLSQPSVVLSGTAIHNFPTVQHQELAK.A "sp|Q9Y520|PRC2C_HUMAN,tr|E7EPN9|E7EPN9_HUMAN,tr|H7C5N8|H7C5N8_HUMAN,tr|A0A2R8Y7F4|A0A2R8Y7F4_HUMAN,tr|A0A2R8YET2|A0A2R8YET2_HUMAN" 5 2887.5192 999 105563 19826 4 2887.515365 722.8871 Protein PRRC2C OS=Homo sapiens OX=9606 GN=PRRC2C PE=1 SV=4 6.66 3211.4 - 667990 - - - -1.3302 - 3.192 0.456 - 61.4 1 1 0 -0.0038 27 0 0 0 8.31E+06 0.00E+00 - - - 3.5571 0.9999 221125_WJC_METTL3_EV_vs_WT_F07.19828.19828.3 2.11E-07 Dec-84 K.ETNDDNYGPGPSLR[166.11]PPNVAC[160.03]WR[166.11].D "sp|Q9Y520|PRC2C_HUMAN,tr|E7EPN9|E7EPN9_HUMAN" 2 2534.1512 1.23 105565 19828 3 2534.153109 845.7243 Protein PRRC2C OS=Homo sapiens OX=9606 GN=PRRC2C PE=1 SV=4 4.56 3211.7 - 748441 - - - 0.7691 - 2.677 0.413 - 94.4 1 2 0 0.0019 22 0 0 0 2.93E+07 2.38E+07 - - - 5.4786 0.9639 221125_WJC_METTL3_EV_vs_WT_F07.19829.19829.3 0.000881 9/112 K.TENGTC[160.03]PSPPQPLSPAAALGSGSAAAVPK[136.11].L sp|Q12948|FOXC1_HUMAN 1 2740.3581 5.28 105566 19829 3 2741.357531 914.46 Forkhead box protein C1 OS=Homo sapiens OX=9606 GN=FOXC1 PE=1 SV=3 5.66 3211.8 - 614190 - - - 364.6921 - 1.418 0.379 - 28.9 1 2 0 0.9994 29 0 0 0 8.02E+07 1.52E+07 - - - 3.2921 0.9597 221125_WJC_METTL3_EV_vs_WT_F07.19835.19835.3 3.72E-05 Jun-92 R.SSFQVLNNPQAQQGC[160.03]SC[160.03]GSSFSIK.L sp|Q86U28|ISCA2_HUMAN 1 2630.1853 7.22 105569 19835 3 2631.177287 877.7357 "Iron-sulfur cluster assembly 2 homolog, mitochondrial OS=Homo sapiens OX=9606 GN=ISCA2 PE=1 SV=2" 7.79 3212.5 - 546190 - - - 377.1415 - 1.68 0.482 - 25.1 1 2 0 0.992 24 0 0 0 5.86E+06 8.11E+05 - - - 4.844 1 221125_WJC_METTL3_EV_vs_WT_F07.19839.19839.3 1.24E-10 23/72 K.LRENSASQISQLEQQLSAK.N "sp|Q13948|CASP_HUMAN,sp|P39880|CUX1_HUMAN,tr|A0A2R8Y852|A0A2R8Y852_HUMAN,tr|A0A2R8YDI1|A0A2R8YDI1_HUMAN" 4 2129.1077 1.31 105571 19839 3 2129.104406 710.7098 Protein CASP OS=Homo sapiens OX=9606 GN=CUX1 PE=1 SV=2 6.14 3213 - 6.03E+06 - - - -1.5283 - 4.4 0.641 - 630.4 1 2 1 -0.0033 19 0 0 0 2.61E+08 1.99E+08 - - - 9.3256 1 221125_WJC_METTL3_EV_vs_WT_F07.19842.19842.3 8.13E-19 26/112 K.KAALDEAQGVGLDSTGYYDQEIYGGSDSR.F "sp|O75533|SF3B1_HUMAN,tr|B4DGZ4|B4DGZ4_HUMAN,tr|A0A494C1M2|A0A494C1M2_HUMAN" 3 3064.3898 1.22 105574 19842 3 3064.387161 1022.4705 Splicing factor 3B subunit 1 OS=Homo sapiens OX=9606 GN=SF3B1 PE=1 SV=3 3.96 3213.3 - 1.41E+06 - - - -0.8507 - 4.344 0.751 - 514.9 1 2 0 -0.0026 29 0 0 0 3.25E+07 2.67E+07 - - - 10.2914 1 221125_WJC_METTL3_EV_vs_WT_F07.19846.19846.3 3.66E-10 17/64 R.KDDPVTNLNNAFEVAEK.Y "sp|O43707|ACTN4_HUMAN,tr|F5GXS2|F5GXS2_HUMAN,tr|H7C144|H7C144_HUMAN" 3 1902.9323 1.24 105576 19846 3 1902.931342 635.3181 Alpha-actinin-4 OS=Homo sapiens OX=9606 GN=ACTN4 PE=1 SV=2 4.32 3213.8 - 762523 - - - -0.5145 - 3.564 0.568 - 587.3 1 2 0 -0.001 17 0 0 0 3.81E+07 3.08E+07 - - - 8.083 1 221125_WJC_METTL3_EV_vs_WT_F07.19856.19856.3 2.31E-15 28/112 K.K[136.11]AALDEAQGVGLDSTGYYDQEIYGGSDSR[166.11].F "sp|O75533|SF3B1_HUMAN,tr|B4DGZ4|B4DGZ4_HUMAN,tr|A0A494C1M2|A0A494C1M2_HUMAN" 3 3082.4122 1.22 105582 19856 3 3082.405971 1028.478 Splicing factor 3B subunit 1 OS=Homo sapiens OX=9606 GN=SF3B1 PE=1 SV=3 3.96 3215 - 1.91E+06 - - - -2.0331 - 5.156 0.769 - 737.3 1 2 0 -0.0063 29 0 0 0 3.25E+07 2.67E+07 - - - 10.8853 1 221125_WJC_METTL3_EV_vs_WT_F07.19862.19862.3 3.50E-10 23/124 R.LDTEAPYC[160.03]GPSSYNQGQESGAGC[160.03]GPGDVFPER.R sp|Q5T749|KPRP_HUMAN 1 3401.4201 999 105586 19862 3 3401.420184 1134.814 Keratinocyte proline-rich protein OS=Homo sapiens OX=9606 GN=KPRP PE=1 SV=1 3.83 3215.7 - 1.41E+06 - - - 0.025 - 3.755 0.737 - 301.5 1 2 0 0.0001 32 0 0 0 3.52E+07 0.00E+00 - - - 9.8007 1 221125_WJC_METTL3_EV_vs_WT_F07.19870.19870.3 1.10E-15 24/104 K.IGEEQSAEDAEDGPPELLFIHGGHTAK[136.11].L "sp|Q16576|RBBP7_HUMAN,tr|Q5JNZ6|Q5JNZ6_HUMAN,tr|E9PC52|E9PC52_HUMAN" 3 2854.3501 1.73 105592 19870 3 2854.34593 952.4573 Histone-binding protein RBBP7 OS=Homo sapiens OX=9606 GN=RBBP7 PE=1 SV=1 4.24 3216.6 - 981519 - - - -1.4546 - 4.601 0.751 - 604.5 1 2 0 -0.0042 27 0 0 0 7.87E+07 4.55E+07 - - - 10.4232 1 221125_WJC_METTL3_EV_vs_WT_F07.19877.19877.3 8.11E-14 33/104 K.IGEEQSAEDAEDGPPELLFIHGGHTAK.L "sp|Q16576|RBBP7_HUMAN,tr|Q5JNZ6|Q5JNZ6_HUMAN,tr|E9PC52|E9PC52_HUMAN" 3 2846.3359 1.61 105597 19877 3 2846.333193 949.7859 Histone-binding protein RBBP7 OS=Homo sapiens OX=9606 GN=RBBP7 PE=1 SV=1 4.24 3217.6 - 1.09E+06 - - - -0.9447 - 5.521 0.768 - 1437 1 2 0 -0.0027 27 0 0 0 7.93E+07 4.94E+07 - - - 11.0325 0.9977 221125_WJC_METTL3_EV_vs_WT_F07.19880.19880.4 0.0134 Sep-96 K.FEPEYSQIKQEVENFKK.V "sp|Q6PKG0|LARP1_HUMAN,tr|A0A0B4J210|A0A0B4J210_HUMAN,tr|H0YC33|H0YC33_HUMAN,tr|E5RH50|E5RH50_HUMAN" 4 2142.0633 0.97 105600 19880 4 2142.061482 536.5231 La-related protein 1 OS=Homo sapiens OX=9606 GN=LARP1 PE=1 SV=2 4.95 3217.9 - 409639 - - - -0.8655 - 1.662 0.332 - 16.8 1 2 1 -0.0019 17 0 0 0 1.52E+07 1.57E+07 - - - 2.2916 0.9999 221125_WJC_METTL3_EV_vs_WT_F07.19885.19885.3 1.24E-09 17/76 K.GLSEDTTEETLKESFDGSVR.A "sp|P19338|NUCL_HUMAN,tr|A0A7I2V699|A0A7I2V699_HUMAN,tr|A0A7I2V2U7|A0A7I2V2U7_HUMAN,tr|A0A7I2V3F3|A0A7I2V3F3_HUMAN,tr|A0A7I2V428|A0A7I2V428_HUMAN,tr|H7BY16|H7BY16_HUMAN,tr|A0A7I2V5M5|A0A7I2V5M5_HUMAN,tr|C9JLB1|C9JLB1_HUMAN" 8 2199.0179 0.96 105602 19885 3 2199.019268 734.0132 Nucleolin OS=Homo sapiens OX=9606 GN=NCL PE=1 SV=3 4.08 3218.6 - 464265 - - - 0.6212 - 3.856 0.529 - 410.4 1 2 1 0.0014 20 0 0 0 9.49E+06 9.84E+06 - - - 7.7117 0.9949 221125_WJC_METTL3_EV_vs_WT_F07.19889.19889.3 0.0027 14/48 S.SHNLQSIFNIGSR.G "sp|P43243|MATR3_HUMAN,tr|A8MXP9|A8MXP9_HUMAN,tr|D6R991|D6R991_HUMAN,tr|D6REK4|D6REK4_HUMAN,tr|A0A0R4J2E8|A0A0R4J2E8_HUMAN,tr|D6RCM3|D6RCM3_HUMAN,tr|D6R8Z5|D6R8Z5_HUMAN,tr|D6REM6|D6REM6_HUMAN" 8 1471.7532 1.07 105606 19889 3 1471.749885 491.5917 Matrin-3 OS=Homo sapiens OX=9606 GN=MATR3 PE=1 SV=2 9.49 3219.1 - 431717 - - - -2.2354 - 2.756 0.5 - 271 1 1 0 -0.0033 13 0 0 0 9.90E+06 9.26E+06 - - - 6.8622 1 221125_WJC_METTL3_EV_vs_WT_F07.19893.19893.3 4.60E-10 17/88 K.EIETYHNLLEGGQEDFESSGAGK.L "sp|P35527|K1C9_HUMAN,tr|K7EQQ3|K7EQQ3_HUMAN" 2 2509.1245 910.02 105608 19893 3 2509.11936 837.3821 "Keratin, type I cytoskeletal 9 OS=Homo sapiens OX=9606 GN=KRT9 PE=1 SV=3" 4.14 3219.6 - 3.24E+06 - - - -2.0453 - 3.618 0.616 - 368.9 1 2 0 -0.0051 23 0 0 0 7.15E+09 7.86E+06 - - - 8.4231 1 221125_WJC_METTL3_EV_vs_WT_F07.19894.19894.4 2.67E-15 26/156 K.IGEEQSPEDAEDGPPELLFIHGGHTAK.L "sp|Q09028|RBBP4_HUMAN,tr|H0YCT5|H0YCT5_HUMAN,tr|H0YDK2|H0YDK2_HUMAN,tr|H0YEU5|H0YEU5_HUMAN,tr|H0YF10|H0YF10_HUMAN" 5 2872.3515 1.94 105609 19894 4 2872.350711 719.0952 Histone-binding protein RBBP4 OS=Homo sapiens OX=9606 GN=RBBP4 PE=1 SV=3 4.24 3219.7 - 2.55E+06 - - - -0.2858 - 4.066 0.715 - 194.6 1 2 0 -0.0008 27 0 0 0 1.41E+09 7.26E+08 - - - 5.888 0.9982 221125_WJC_METTL3_EV_vs_WT_F07.19895.19895.3 3.61E-08 Oct-48 S.SHNLQSIFNIGSR[166.11].G "sp|P43243|MATR3_HUMAN,tr|A8MXP9|A8MXP9_HUMAN,tr|D6R991|D6R991_HUMAN,tr|D6REK4|D6REK4_HUMAN,tr|A0A0R4J2E8|A0A0R4J2E8_HUMAN,tr|D6RCM3|D6RCM3_HUMAN,tr|D6R8Z5|D6R8Z5_HUMAN,tr|D6REM6|D6REM6_HUMAN" 8 1481.7614 1.07 105610 19895 3 1481.760509 494.9278 Matrin-3 OS=Homo sapiens OX=9606 GN=MATR3 PE=1 SV=2 9.49 3219.8 - 602289 - - - -0.6317 - 2.547 0.554 - 116.5 1 1 0 -0.0009 13 0 0 0 9.90E+06 9.26E+06 - - - 7.2511 1 221125_WJC_METTL3_EV_vs_WT_F07.19896.19896.3 1.17E-11 17/112 R.SRVEEPSGAVTTPAGVIAAAGPQGPGTGE.- sp|P85037|FOXK1_HUMAN 1 2662.3198 2.01 105611 19896 3 2662.315628 888.4472 Forkhead box protein K1 OS=Homo sapiens OX=9606 GN=FOXK1 PE=1 SV=1 4.52 3220 - 460958 - - - -1.5813 - 3.567 0.635 - 251.5 1 2 1 -0.0042 29 0 0 0 2.69E+07 1.34E+07 - - - 8.5442 0.9996 221125_WJC_METTL3_EV_vs_WT_F07.19901.19901.4 1.43E-05 18/162 R.QLPAQPPEHAVDGEGFK[136.11]NTLETSSLNFK[136.11].V "sp|Q14151|SAFB2_HUMAN,tr|K7ERX3|K7ERX3_HUMAN,tr|K7EQU4|K7EQU4_HUMAN" 3 3069.5378 3.09 105613 19901 4 3069.535114 768.3917 Scaffold attachment factor B2 OS=Homo sapiens OX=9606 GN=SAFB2 PE=1 SV=1 4.83 3220.7 - 692756 - - - -0.8848 - 2.688 0.42 - 128.4 1 2 1 -0.0027 28 0 0 0 4.92E+07 1.59E+07 - - - 3.1879 1 221125_WJC_METTL3_EV_vs_WT_F07.19904.19904.4 1.33E-10 24/120 F.ASFNDTFVHVTDLSGK[136.11]ETIC[160.03]R[166.11].V "sp|P62263|RS14_HUMAN,tr|A0A2R8Y811|A0A2R8Y811_HUMAN,tr|E5RH77|E5RH77_HUMAN" 3 2414.1655 1.42 105615 19904 4 2414.166996 604.5487 40S ribosomal protein S14 OS=Homo sapiens OX=9606 GN=RPS14 PE=1 SV=3 5.38 3221 - 1.03E+06 - - - 0.6072 - 4.474 0.637 - 551.1 1 1 1 0.0015 21 0 0 0 2.11E+07 1.48E+07 - - - 5.2654 0.9925 221125_WJC_METTL3_EV_vs_WT_F07.19906.19906.4 8.06E-10 27/120 F.ASFNDTFVHVTDLSGKETIC[160.03]R.V "sp|P62263|RS14_HUMAN,tr|A0A2R8Y811|A0A2R8Y811_HUMAN,tr|E5RH77|E5RH77_HUMAN" 3 2396.1431 1.43 105617 19906 4 2396.142429 600.043 40S ribosomal protein S14 OS=Homo sapiens OX=9606 GN=RPS14 PE=1 SV=3 5.38 3221.2 - 808349 - - - -0.2633 - 4.688 0.571 - 720.9 1 1 1 -0.0006 21 0 0 0 2.11E+07 1.47E+07 - - - 4.7066 1 221125_WJC_METTL3_EV_vs_WT_F07.19907.19907.4 1.06E-08 19/162 K.ESASQHITEEEDDDPDVYYFESDHVALK.H sp|Q8IYH5|ZZZ3_HUMAN 1 3267.4004 2.72 105618 19907 4 3267.40958 817.8574 ZZ-type zinc finger-containing protein 3 OS=Homo sapiens OX=9606 GN=ZZZ3 PE=1 SV=1 3.92 3221.4 - 782056 - - - 2.812 - 3.641 0.66 - 198.3 1 2 0 0.0092 28 0 0 0 6.63E+06 2.44E+06 - - - 5.3693 1 221125_WJC_METTL3_EV_vs_WT_F07.19915.19915.4 2.11E-07 22/102 K.RPENSLLEETLHFDHAVR.M "sp|O00566|MPP10_HUMAN,tr|U3KQ48|U3KQ48_HUMAN" 2 2162.0869 180.97 105623 19915 4 2162.089669 541.529 U3 small nucleolar ribonucleoprotein protein MPP10 OS=Homo sapiens OX=9606 GN=MPHOSPH10 PE=1 SV=2 5.36 3222.4 - 1.11E+06 - - - 1.2969 - 3.517 0.586 - 338.1 1 2 0 0.0028 18 0 0 0 7.62E+07 4.21E+05 - - - 4.7566 1 221125_WJC_METTL3_EV_vs_WT_F07.19925.19925.2 6.80E-12 25/44 K.EIETYHNLLEGGQEDFESSGAGK.L "sp|P35527|K1C9_HUMAN,tr|K7EQQ3|K7EQQ3_HUMAN" 2 2509.1245 999 105630 19925 2 2509.123729 1255.5695 "Keratin, type I cytoskeletal 9 OS=Homo sapiens OX=9606 GN=KRT9 PE=1 SV=3" 4.14 3223.5 - 1.17E+06 - - - -0.3041 - 5.16 0.781 - 2132.8 1 2 0 -0.0008 23 0 0 0 1.09E+08 0.00E+00 - - - 8.8435 1 221125_WJC_METTL3_EV_vs_WT_F07.19927.19927.3 1.22E-19 25/104 K.IGEEQSPEDAEDGPPELLFIHGGHTAK.L "sp|Q09028|RBBP4_HUMAN,tr|H0YCT5|H0YCT5_HUMAN,tr|H0YDK2|H0YDK2_HUMAN,tr|H0YEU5|H0YEU5_HUMAN,tr|H0YF10|H0YF10_HUMAN" 5 2872.3515 2.52 105632 19927 3 2872.352875 958.4578 Histone-binding protein RBBP4 OS=Homo sapiens OX=9606 GN=RBBP4 PE=1 SV=3 4.24 3223.7 - 843652 - - - 0.4676 - 5.046 0.753 - 695.3 1 2 0 0.0013 27 0 0 0 6.91E+07 2.74E+07 - - - 10.6586 0.9461 221125_WJC_METTL3_EV_vs_WT_F07.19928.19928.3 5.20E-07 22/112 K.IQIASESSGIPERPC[160.03]VLTGTPESIEQAK[136.11]R[166.11].L sp|Q96I24|FUBP3_HUMAN 1 3170.636 - 105633 19928 3 3171.607724 1057.886 Far upstream element-binding protein 3 OS=Homo sapiens OX=9606 GN=FUBP3 PE=1 SV=2 4.95 3223.9 - 820780 - - - 306.4612 - 3.04 0.583 - 337.5 1 2 0 0.9717 29 0 0 0 - - - - - 7.3287 1 221125_WJC_METTL3_EV_vs_WT_F07.19934.19934.3 8.74E-19 33/124 K.ADPAFGLESSGIAGTTSDEPERIEESGNDEAR.V "sp|Q8TAQ2|SMRC2_HUMAN,tr|F8VXC8|F8VXC8_HUMAN" 2 3306.476 5.05 105636 19934 3 3306.465198 1103.1659 SWI\SNF complex subunit SMARCC2 OS=Homo sapiens OX=9606 GN=SMARCC2 PE=1 SV=1 3.84 3224.6 - 1.23E+06 - - - -3.2721 - 5.279 0.718 - 987.5 1 2 1 -0.0108 32 0 0 0 2.76E+07 5.46E+06 - - - 10.3696 1 221125_WJC_METTL3_EV_vs_WT_F07.19937.19937.3 1.43E-10 19/76 R.DTPENNPDTPFDFTPENYK[136.11]R[166.11].L "sp|P19404|NDUV2_HUMAN,tr|E7EPT4|E7EPT4_HUMAN" 2 2414.0782 1.79 105638 19937 3 2414.066457 805.7 "NADH dehydrogenase [ubiquinone] flavoprotein 2, mitochondrial OS=Homo sapiens OX=9606 GN=NDUFV2 PE=1 SV=2" 4.11 3224.9 - 612927 - - - -4.8453 - 3.362 0.652 - 302 1 2 0 -0.0117 20 0 0 0 5.34E+07 2.97E+07 - - - 8.7476 0.9927 221125_WJC_METTL3_EV_vs_WT_F07.19938.19938.3 1.07E-06 16/100 S.SSLNQQGAHSALSSASTSSHNLQSIF.- tr|D6RBS2|D6RBS2_HUMAN 1 2658.2634 - 105639 19938 3 2658.256663 887.0951 Matrin-3 (Fragment) OS=Homo sapiens OX=9606 GN=MATR3 PE=1 SV=1 6.66 3225.1 - 966620 - - - -2.5291 - 3.003 0.502 - 187.6 1 1 0 -0.0067 26 0 0 0 - - - - - 6.6648 1 221125_WJC_METTL3_EV_vs_WT_F07.19939.19939.3 3.93E-12 24/104 R.YYGQNGQQILSASQDGTLQSFSTVHEK[136.11].F "sp|Q8NI36|WDR36_HUMAN,tr|A0A0A0MTB8|A0A0A0MTB8_HUMAN" 2 2993.4246 1.04 105640 19939 3 2993.416275 998.8155 WD repeat-containing protein 36 OS=Homo sapiens OX=9606 GN=WDR36 PE=1 SV=1 5.32 3225.2 - 955874 - - - -2.7958 - 4.233 0.685 - 492 1 2 0 -0.0084 27 0 0 0 4.46E+07 4.28E+07 - - - 9.4944 1 221125_WJC_METTL3_EV_vs_WT_F07.19943.19943.3 4.09E-14 25/104 R.YYGQNGQQILSASQDGTLQSFSTVHEK.F "sp|Q8NI36|WDR36_HUMAN,tr|A0A0A0MTB8|A0A0A0MTB8_HUMAN" 2 2985.4104 1.04 105642 19943 3 2985.407998 996.1441 WD repeat-containing protein 36 OS=Homo sapiens OX=9606 GN=WDR36 PE=1 SV=1 5.32 3225.7 - 1.27E+06 - - - -0.8193 - 4.356 0.646 - 506.1 1 2 0 -0.0024 27 0 0 0 4.46E+07 4.28E+07 - - - 9.1271 1 221125_WJC_METTL3_EV_vs_WT_F07.19947.19947.4 1.79E-08 15/120 R.SHFEQWGTLTDC[160.03]VVMRDPNTK.R "sp|Q32P51|RA1L2_HUMAN,sp|P09651|ROA1_HUMAN,tr|F8W646|F8W646_HUMAN,tr|F8VZ49|F8VZ49_HUMAN,tr|A0A7I2V3R8|A0A7I2V3R8_HUMAN,tr|F8W6I7|F8W6I7_HUMAN,tr|A0A7I2V2L6|A0A7I2V2L6_HUMAN,tr|A0A7I2V3W0|A0A7I2V3W0_HUMAN" 8 2520.1526 1.15 105644 19947 4 2520.146534 631.0454 Heterogeneous nuclear ribonucleoprotein A1-like 2 OS=Homo sapiens OX=9606 GN=HNRNPA1L2 PE=2 SV=2 5.36 3226.2 - 929257 - - - -2.3983 - 2.864 0.632 - 169.5 1 2 1 -0.006 21 0 0 0 2.53E+07 2.20E+07 - - - 5.0732 1 221125_WJC_METTL3_EV_vs_WT_F07.19949.19949.3 2.55E-11 21/76 R.DTPENNPDTPFDFTPENYKR.L "sp|P19404|NDUV2_HUMAN,tr|E7EPT4|E7EPT4_HUMAN" 2 2396.0557 1.79 105645 19949 3 2396.053989 799.6925 "NADH dehydrogenase [ubiquinone] flavoprotein 2, mitochondrial OS=Homo sapiens OX=9606 GN=NDUFV2 PE=1 SV=2" 4.11 3226.4 - 1.44E+06 - - - -0.7074 - 3.561 0.675 - 386.6 1 2 0 -0.0017 20 0 0 0 5.34E+07 2.97E+07 - - - 9.1463 1 221125_WJC_METTL3_EV_vs_WT_F07.19954.19954.3 2.26E-13 23/80 K.AQQIHSQTSQQYPLYDLDLGK.F sp|P15924|DESP_HUMAN 1 2432.1972 24.09 105648 19954 3 2432.197131 811.7397 Desmoplakin OS=Homo sapiens OX=9606 GN=DSP PE=1 SV=3 5.21 3227.1 - 513560 - - - -0.0296 - 4.756 0.692 - 603.1 1 2 0 -0.0001 21 0 0 0 5.01E+08 2.08E+07 - - - 9.9937 0.9999 221125_WJC_METTL3_EV_vs_WT_F07.19957.19957.3 1.06E-05 21/92 R.ELLESNFTLVGDDGTNK[136.11]EATSTGK[136.11].L sp|Q96A33|CCD47_HUMAN 1 2541.2417 1.44 105651 19957 3 2541.238368 848.0878 PAT complex subunit CCDC47 OS=Homo sapiens OX=9606 GN=CCDC47 PE=1 SV=1 4.18 3227.4 - 1.04E+06 - - - -1.3139 - 4.153 0.59 - 346.3 1 2 1 -0.0033 24 0 0 0 1.64E+07 1.13E+07 - - - 8.424 0.9999 221125_WJC_METTL3_EV_vs_WT_F07.19962.19962.3 0.00193 15/64 K.EIK[136.11]DTEK[136.11]EVDDLTAELK[136.11].S "sp|Q9NTJ3|SMC4_HUMAN,tr|E9PD53|E9PD53_HUMAN" 2 1999.0423 0.7 105654 19962 3 1999.043556 667.3547 Structural maintenance of chromosomes protein 4 OS=Homo sapiens OX=9606 GN=SMC4 PE=1 SV=2 4.2 3228.1 - 541932 - - - 0.6123 - 3.088 0.529 - 221.5 1 2 2 0.0012 17 0 0 0 2.22E+07 3.17E+07 - - - 7.286 0.9485 221125_WJC_METTL3_EV_vs_WT_F07.19971.19971.4 0.0484 Sep-96 K.EIK[136.11]DTEK[136.11]EVDDLTAELK[136.11].S "sp|Q9NTJ3|SMC4_HUMAN,tr|E9PD53|E9PD53_HUMAN" 2 1999.0423 0.77 105659 19971 4 1999.033447 500.7679 Structural maintenance of chromosomes protein 4 OS=Homo sapiens OX=9606 GN=SMC4 PE=1 SV=2 4.2 3229.2 - 540391 - - - -4.4446 - 1.823 0.28 - 74.2 1 2 2 -0.0089 17 0 0 0 1.06E+07 1.38E+07 - - - 1.8691 1 221125_WJC_METTL3_EV_vs_WT_F07.19986.19986.3 5.63E-14 36/104 K.IGEEQSPEDAEDGPPELLFIHGGHTAK[136.11].L "sp|Q09028|RBBP4_HUMAN,tr|H0YCT5|H0YCT5_HUMAN,tr|H0YDK2|H0YDK2_HUMAN,tr|H0YEU5|H0YEU5_HUMAN,tr|H0YF10|H0YF10_HUMAN" 5 2880.3657 2.05 105668 19986 3 2880.363516 961.1292 Histone-binding protein RBBP4 OS=Homo sapiens OX=9606 GN=RBBP4 PE=1 SV=3 4.24 3231.1 - 1.52E+06 - - - -0.7693 - 5.687 0.757 - 1624.6 1 2 0 -0.0022 27 0 0 0 1.49E+08 7.26E+07 - - - 10.9781 0.9999 221125_WJC_METTL3_EV_vs_WT_F07.19987.19987.3 3.43E-09 16/64 K.EIKDTEKEVDDLTAELK.S "sp|Q9NTJ3|SMC4_HUMAN,tr|E9PD53|E9PD53_HUMAN" 2 1974.9997 0.72 105669 19987 3 1975.003364 659.3405 Structural maintenance of chromosomes protein 4 OS=Homo sapiens OX=9606 GN=SMC4 PE=1 SV=2 4.2 3231.2 - 671502 - - - 1.839 - 3.444 0.558 - 320.1 1 2 2 0.0036 17 0 0 0 2.30E+07 3.17E+07 - - - 7.8843 0.9991 221125_WJC_METTL3_EV_vs_WT_F07.19988.19988.4 0.00114 13/96 K.EIKDTEKEVDDLTAELK.S "sp|Q9NTJ3|SMC4_HUMAN,tr|E9PD53|E9PD53_HUMAN" 2 1974.9997 0.77 105670 19988 4 1974.999276 494.7572 Structural maintenance of chromosomes protein 4 OS=Homo sapiens OX=9606 GN=SMC4 PE=1 SV=2 4.2 3231.3 - 448436 - - - -0.2309 - 2.213 0.37 - 149.3 1 2 2 -0.0005 17 0 0 0 1.06E+07 1.38E+07 - - - 2.7221 0.9897 221125_WJC_METTL3_EV_vs_WT_F07.19989.19989.3 3.43E-07 13/56 S.TSSHNLQSIFNIGSR.G "sp|P43243|MATR3_HUMAN,tr|A8MXP9|A8MXP9_HUMAN,tr|D6R991|D6R991_HUMAN,tr|D6REK4|D6REK4_HUMAN,tr|A0A0R4J2E8|A0A0R4J2E8_HUMAN,tr|D6RCM3|D6RCM3_HUMAN,tr|D6R8Z5|D6R8Z5_HUMAN,tr|D6REM6|D6REM6_HUMAN" 8 1659.8329 1.25 105671 19989 3 1659.833107 554.2849 Matrin-3 OS=Homo sapiens OX=9606 GN=MATR3 PE=1 SV=2 9.44 3231.5 - 435365 - - - 0.1356 - 2.442 0.389 - 174.8 1 1 0 0.0002 15 0 0 0 1.64E+07 1.31E+07 - - - 5.2066 0.9747 221125_WJC_METTL3_EV_vs_WT_F07.19990.19990.3 2.81E-05 Oct-72 R.NR[166.11]DNDPNDYVEQDDILIVK[136.11].L sp|P19387|RPB3_HUMAN 1 2292.0989 1.3 105672 19990 3 2292.085994 765.0402 DNA-directed RNA polymerase II subunit RPB3 OS=Homo sapiens OX=9606 GN=POLR2C PE=1 SV=2 3.9 3231.6 - 399480 - - - -5.6263 - 1.745 0.409 - 95.1 1 2 1 -0.0129 19 0 0 0 1.79E+07 1.37E+07 - - - 4.4642 1 221125_WJC_METTL3_EV_vs_WT_F07.19994.19994.4 4.36E-08 17/150 K.GYEEVHVPALK[136.11]PK[136.11]PFGSEEQLLPVEK[136.11].L "sp|O75643|U520_HUMAN,tr|A0A494C1A5|A0A494C1A5_HUMAN" 2 2943.5808 2.21 105674 19994 4 2943.587233 736.9025 U5 small nuclear ribonucleoprotein 200 kDa helicase OS=Homo sapiens OX=9606 GN=SNRNP200 PE=1 SV=2 5.02 3232.1 - 656766 - - - 2.1817 - 3.076 0.573 - 92.9 1 2 0 0.0064 26 0 0 0 7.26E+07 3.29E+07 - - - 4.566 0.9999 221125_WJC_METTL3_EV_vs_WT_F07.19995.19995.3 9.66E-06 17/52 K.NKLNDLEDALQQAK.E sp|P04264|K2C1_HUMAN 1 1598.8264 8323.68 105675 19995 3 1598.827087 533.9494 "Keratin, type II cytoskeletal 1 OS=Homo sapiens OX=9606 GN=KRT1 PE=1 SV=6" 4.56 3232.3 - 744816 - - - 0.4297 - 3.195 0.471 - 248.6 1 2 1 0.0007 14 0 0 0 8.85E+08 1.06E+05 - - - 6.878 0.9939 221125_WJC_METTL3_EV_vs_WT_F07.19997.19997.3 8.02E-07 14/56 S.TSSHNLQSIFNIGSR[166.11].G "sp|P43243|MATR3_HUMAN,tr|A8MXP9|A8MXP9_HUMAN,tr|D6R991|D6R991_HUMAN,tr|D6REK4|D6REK4_HUMAN,tr|A0A0R4J2E8|A0A0R4J2E8_HUMAN,tr|D6RCM3|D6RCM3_HUMAN,tr|D6R8Z5|D6R8Z5_HUMAN,tr|D6REM6|D6REM6_HUMAN" 8 1669.8412 1.27 105677 19997 3 1669.843316 557.621 Matrin-3 OS=Homo sapiens OX=9606 GN=MATR3 PE=1 SV=2 9.44 3232.5 - 483675 - - - 1.2959 - 2.642 0.442 - 203.2 1 1 0 0.0022 15 0 0 0 1.68E+07 1.32E+07 - - - 6.0024 1 221125_WJC_METTL3_EV_vs_WT_F07.19999.19999.3 1.72E-07 Nov-68 K.YVHYEIDAC[160.03]MDSEAPGSK[136.11].D "sp|Q86U44|MTA70_HUMAN,tr|H0YFV6|H0YFV6_HUMAN" 2 2078.8805 -1 105679 19999 3 2078.87923 693.9674 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 4.31 3232.8 - 213488 - - - -0.6071 - 2.175 0.625 - 123.1 1 2 0 -0.0013 18 0 0 0 0.00E+00 0.00E+00 - - - 7.4427 1 221125_WJC_METTL3_EV_vs_WT_F07.20002.20002.3 1.43E-15 24/124 R.NC[160.03]VGSSLPEASPPAPEPSSPNAAVPEAIPTPR.A sp|P57086|SCND1_HUMAN 1 3195.5506 4.26 105680 20002 3 3195.550832 1066.1908 SCAN domain-containing protein 1 OS=Homo sapiens OX=9606 GN=SCAND1 PE=1 SV=1 4.25 3233.2 - 358934 - - - 0.0591 - 4.049 0.737 - 269.7 1 2 0 0.0002 32 0 0 0 4.44E+07 1.04E+07 - - - 9.9741 0.9999 221125_WJC_METTL3_EV_vs_WT_F07.20005.20005.4 5.47E-05 11/108 R.GLLQDDAHPTLVTYADHSK[136.11].L "sp|Q86U44|MTA70_HUMAN,tr|F5H6D8|F5H6D8_HUMAN,tr|H0YFV6|H0YFV6_HUMAN,tr|B4DTN4|B4DTN4_HUMAN" 4 2088.0367 0.1 105683 20005 4 2088.033363 523.0165 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 5.13 3233.6 - 380238 - - - -1.614 - 2.361 0.406 - 124 1 2 0 -0.0034 19 0 0 0 5.31E+05 5.33E+06 - - - 3.0495 0.9999 221125_WJC_METTL3_EV_vs_WT_F07.20006.20006.3 2.30E-05 16/64 R.GAPPSSNIEDFHGLLPK.G "sp|P43243|MATR3_HUMAN,tr|A8MXP9|A8MXP9_HUMAN,tr|D6R991|D6R991_HUMAN,tr|A0A0R4J2E8|A0A0R4J2E8_HUMAN,tr|H0Y8T4|H0Y8T4_HUMAN,tr|D6REM6|D6REM6_HUMAN" 6 1777.8999 1.31 105684 20006 3 1777.899787 593.6406 Matrin-3 OS=Homo sapiens OX=9606 GN=MATR3 PE=1 SV=2 5.32 3233.7 - 375126 - - - -0.063 - 2.256 0.438 - 227.8 1 2 0 -0.0001 17 0 0 0 1.01E+08 7.71E+07 - - - 5.4786 1 221125_WJC_METTL3_EV_vs_WT_F07.20013.20013.3 1.37E-11 16/104 R.QLAPGMVQQMQSVC[160.03]SDC[160.03]NGEGEVINEK.D "sp|O60884|DNJA2_HUMAN,tr|A0A087WT48|A0A087WT48_HUMAN" 2 3007.3144 0.48 105689 20013 3 3007.314698 1003.4454 DnaJ homolog subfamily A member 2 OS=Homo sapiens OX=9606 GN=DNAJA2 PE=1 SV=1 4 3234.6 - 640238 - - - 0.1067 - 3.616 0.677 - 246.3 1 2 0 0.0003 27 0 0 0 9.86E+06 2.05E+07 - - - 9.045 1 221125_WJC_METTL3_EV_vs_WT_F07.20020.20020.2 7.06E-08 19/26 K.NKLNDLEDALQQAK.E sp|P04264|K2C1_HUMAN 1 1598.8264 999 105694 20020 2 1598.828179 800.4205 "Keratin, type II cytoskeletal 1 OS=Homo sapiens OX=9606 GN=KRT1 PE=1 SV=6" 4.56 3235.4 - 1.65E+06 - - - 1.1127 - 3.77 0.6 - 1366 1 2 1 0.0018 14 0 0 0 2.77E+08 0.00E+00 - - - 6.8023 1 221125_WJC_METTL3_EV_vs_WT_F07.20032.20032.3 1.24E-07 14/64 R.GAPPSSNIEDFHGLLPK[136.11].G "sp|P43243|MATR3_HUMAN,tr|A8MXP9|A8MXP9_HUMAN,tr|D6R991|D6R991_HUMAN,tr|A0A0R4J2E8|A0A0R4J2E8_HUMAN,tr|H0Y8T4|H0Y8T4_HUMAN,tr|D6REM6|D6REM6_HUMAN" 6 1785.9141 1.32 105701 20032 3 1785.914528 596.312 Matrin-3 OS=Homo sapiens OX=9606 GN=MATR3 PE=1 SV=2 5.32 3236.9 - 716651 - - - 0.2402 - 2.718 0.497 - 207.7 1 2 0 0.0004 17 0 0 0 9.96E+07 7.54E+07 - - - 6.607 0.9901 221125_WJC_METTL3_EV_vs_WT_F07.20039.20039.4 0.00242 14/168 Q.VVSSDFNSDTHSSTFDAGAGIALNDHFVK[136.11].L "sp|P04406|G3P_HUMAN,tr|E7EUT5|E7EUT5_HUMAN" 2 3045.4196 0.72 105706 20039 4 3045.411796 762.3622 Glyceraldehyde-3-phosphate dehydrogenase OS=Homo sapiens OX=9606 GN=GAPDH PE=1 SV=3 4.54 3237.8 - 1.15E+06 - - - -2.5487 - 2.605 0.497 - 77.1 1 1 0 -0.0078 29 0 0 0 3.27E+07 4.55E+07 - - - 3.8448 1 221125_WJC_METTL3_EV_vs_WT_F07.20047.20047.4 2.91E-11 25/150 K.GYEEVHVPALKPKPFGSEEQLLPVEK.L "sp|O75643|U520_HUMAN,tr|A0A494C1A5|A0A494C1A5_HUMAN" 2 2919.5382 2.05 105710 20047 4 2919.537774 730.8918 U5 small nuclear ribonucleoprotein 200 kDa helicase OS=Homo sapiens OX=9606 GN=SNRNP200 PE=1 SV=2 5.02 3238.9 - 1.77E+06 - - - -0.1497 - 3.666 0.599 - 220.7 1 2 0 -0.0004 26 0 0 0 4.44E+07 2.17E+07 - - - 4.8494 1 221125_WJC_METTL3_EV_vs_WT_F07.20061.20061.3 1.16E-07 16/80 K.AQQIHSQTSQQYPLYDLDLGK[136.11].F sp|P15924|DESP_HUMAN 1 2440.2114 24.09 105719 20061 3 2440.208799 814.4111 Desmoplakin OS=Homo sapiens OX=9606 GN=DSP PE=1 SV=3 5.21 3240.6 - 383929 - - - -1.0671 - 3.107 0.603 - 252.2 1 2 0 -0.0026 21 0 0 0 5.01E+08 2.08E+07 - - - 7.98 0.9993 221125_WJC_METTL3_EV_vs_WT_F07.20067.20067.4 0.0104 Oct-90 K.AKVDLKPLLSSLSANK.E "sp|Q9NRA8|4ET_HUMAN,tr|B1AKL4|B1AKL4_HUMAN,tr|B0QYZ7|B0QYZ7_HUMAN" 3 1682.9931 1.15 105722 20067 4 1682.99344 421.7555 Eukaryotic translation initiation factor 4E transporter OS=Homo sapiens OX=9606 GN=EIF4ENIF1 PE=1 SV=2 9.7 3241.4 - 207767 - - - 0.2193 - 1.619 0.404 - 59.1 1 2 1 0.0004 16 0 0 0 1.42E+07 1.23E+07 - - - 2.912 0.9965 221125_WJC_METTL3_EV_vs_WT_F07.20069.20069.3 1.09E-06 20/108 R.AAASSYNTQGAASSLGSYGAQAASYGAQ.S sp|Q96PK6|RBM14_HUMAN 1 2609.163 - 105723 20069 3 2609.161997 870.7283 RNA-binding protein 14 OS=Homo sapiens OX=9606 GN=RBM14 PE=1 SV=2 5.57 3241.6 - 2.84E+06 - - - -0.3856 - 4.332 0.4 - 368.5 1 1 0 -0.001 28 0 0 0 - - - - - 6.3721 0.9999 221125_WJC_METTL3_EV_vs_WT_F07.20072.20072.3 5.04E-07 13/84 K.TK[136.11]GHLDAELDAYMAQTDPETND.- "sp|Q9Y3Y2|CHTOP_HUMAN,tr|X6R700|X6R700_HUMAN" 2 2442.0736 1.64 105725 20072 3 2442.073789 815.0318 Chromatin target of PRMT1 protein OS=Homo sapiens OX=9606 GN=CHTOP PE=1 SV=2 4.1 3241.9 - 555253 - - - 0.0573 - 2.696 0.549 - 133.8 1 2 1 0.0001 22 0 0 0 6.50E+07 3.97E+07 - - - 7.0121 0.9988 221125_WJC_METTL3_EV_vs_WT_F07.20076.20076.3 5.79E-08 19/60 A.STSSHNLQSIFNIGSR[166.11].G "sp|P43243|MATR3_HUMAN,tr|A8MXP9|A8MXP9_HUMAN,tr|D6R991|D6R991_HUMAN,tr|D6REK4|D6REK4_HUMAN,tr|A0A0R4J2E8|A0A0R4J2E8_HUMAN,tr|D6RCM3|D6RCM3_HUMAN,tr|D6R8Z5|D6R8Z5_HUMAN,tr|D6REM6|D6REM6_HUMAN" 8 1756.8732 1.32 105727 20076 3 1756.874617 586.6317 Matrin-3 OS=Homo sapiens OX=9606 GN=MATR3 PE=1 SV=2 9.49 3242.5 - 1.94E+06 - - - 0.8174 - 3.304 0.574 - 458.2 1 1 0 0.0014 16 0 0 0 2.82E+08 2.14E+08 - - - 8.0057 1 221125_WJC_METTL3_EV_vs_WT_F07.20077.20077.3 3.00E-09 19/60 A.STSSHNLQSIFNIGSR.G "sp|P43243|MATR3_HUMAN,tr|A8MXP9|A8MXP9_HUMAN,tr|D6R991|D6R991_HUMAN,tr|D6REK4|D6REK4_HUMAN,tr|A0A0R4J2E8|A0A0R4J2E8_HUMAN,tr|D6RCM3|D6RCM3_HUMAN,tr|D6R8Z5|D6R8Z5_HUMAN,tr|D6REM6|D6REM6_HUMAN" 8 1746.8649 1.34 105728 20077 3 1746.868185 583.2956 Matrin-3 OS=Homo sapiens OX=9606 GN=MATR3 PE=1 SV=2 9.49 3242.5 - 1.99E+06 - - - 1.8742 - 3.592 0.627 - 497.7 1 1 0 0.0033 16 0 0 0 2.87E+08 2.14E+08 - - - 8.8105 0.9994 221125_WJC_METTL3_EV_vs_WT_F07.20078.20078.4 0.00067 Nov-90 K.AK[136.11]VDLK[136.11]PLLSSLSANK[136.11].E "sp|Q9NRA8|4ET_HUMAN,tr|B1AKL4|B1AKL4_HUMAN,tr|B0QYZ7|B0QYZ7_HUMAN" 3 1707.0357 1.15 105729 20078 4 1707.034705 427.7662 Eukaryotic translation initiation factor 4E transporter OS=Homo sapiens OX=9606 GN=EIF4ENIF1 PE=1 SV=2 9.7 3242.7 - 394523 - - - -0.5659 - 1.854 0.407 - 76.2 1 2 1 -0.001 16 0 0 0 1.41E+07 1.23E+07 - - - 2.9857 0.998 221125_WJC_METTL3_EV_vs_WT_F07.20086.20086.3 2.05E-07 14/64 S.ASTSSHNLQSIFNIGSR.G "sp|P43243|MATR3_HUMAN,tr|A8MXP9|A8MXP9_HUMAN,tr|D6R991|D6R991_HUMAN,tr|D6REK4|D6REK4_HUMAN,tr|A0A0R4J2E8|A0A0R4J2E8_HUMAN,tr|D6RCM3|D6RCM3_HUMAN,tr|D6R8Z5|D6R8Z5_HUMAN,tr|D6REM6|D6REM6_HUMAN" 8 1817.902 0.9 105735 20086 3 1817.904876 606.9746 Matrin-3 OS=Homo sapiens OX=9606 GN=MATR3 PE=1 SV=2 9.8 3243.6 - 540700 - - - 1.5688 - 2.796 0.597 - 242.7 1 1 0 0.0029 17 0 0 0 4.11E+07 4.56E+07 - - - 7.7927 0.999 221125_WJC_METTL3_EV_vs_WT_F07.20090.20090.4 0.0255 11/138 K.FTGTNIAPDEHVQPQLMFDYDGKR.D sp|O95391|SLU7_HUMAN 1 2778.3072 1.14 105737 20090 4 2778.312846 695.5841 Pre-mRNA-splicing factor SLU7 OS=Homo sapiens OX=9606 GN=SLU7 PE=1 SV=2 4.66 3244.1 - 479268 - - - 2.0448 - 2.24 0.32 - 61.5 1 2 0 0.0057 24 0 0 0 9.48E+06 8.34E+06 - - - 2.2686 0.9932 221125_WJC_METTL3_EV_vs_WT_F07.20092.20092.3 9.11E-07 16/64 S.ASTSSHNLQSIFNIGSR[166.11].G "sp|P43243|MATR3_HUMAN,tr|A8MXP9|A8MXP9_HUMAN,tr|D6R991|D6R991_HUMAN,tr|D6REK4|D6REK4_HUMAN,tr|A0A0R4J2E8|A0A0R4J2E8_HUMAN,tr|D6RCM3|D6RCM3_HUMAN,tr|D6R8Z5|D6R8Z5_HUMAN,tr|D6REM6|D6REM6_HUMAN" 8 1827.9103 1.17 105739 20092 3 1827.91492 610.3107 Matrin-3 OS=Homo sapiens OX=9606 GN=MATR3 PE=1 SV=2 9.8 3244.4 - 804002 - - - 2.5308 - 2.584 0.529 - 271.6 1 1 0 0.0046 17 0 0 0 3.71E+07 3.18E+07 - - - 6.8349 1 221125_WJC_METTL3_EV_vs_WT_F07.20100.20100.4 2.41E-11 19/144 R.LGATIEHISVSPAGDLFC[160.03]TSHSDNK[136.11].L sp|Q8IWA0|WDR75_HUMAN 1 2663.2741 1.36 105745 20100 4 2663.27397 666.8258 WD repeat-containing protein 75 OS=Homo sapiens OX=9606 GN=WDR75 PE=1 SV=1 5.21 3245.4 - 685986 - - - -0.0413 - 4.024 0.607 - 263.8 1 2 0 -0.0001 25 0 0 0 3.19E+07 2.34E+07 - - - 4.9522 0.9996 221125_WJC_METTL3_EV_vs_WT_F07.20102.20102.4 1.53E-05 14/108 K.NTKEPPLSLTIHLTSPVVR.E "sp|Q12906|ILF3_HUMAN,tr|K7EQR9|K7EQR9_HUMAN,tr|K7EKY0|K7EKY0_HUMAN,tr|K7EPG3|K7EPG3_HUMAN,tr|K7EKJ9|K7EKJ9_HUMAN" 5 2101.1895 0.8 105747 20102 4 2101.194558 526.3047 Interleukin enhancer-binding factor 3 OS=Homo sapiens OX=9606 GN=ILF3 PE=1 SV=3 8.75 3245.7 - 164553 - - - 2.3886 - 2.845 0.464 - 158.3 1 2 1 0.005 19 0 0 0 4.74E+06 5.96E+06 - - - 3.617 1 221125_WJC_METTL3_EV_vs_WT_F07.20105.20105.3 2.70E-08 18/60 K.AKVDLKPLLSSLSANK.E "sp|Q9NRA8|4ET_HUMAN,tr|B1AKL4|B1AKL4_HUMAN,tr|B0QYZ7|B0QYZ7_HUMAN" 3 1682.9931 1.19 105748 20105 3 1682.995068 562.005 Eukaryotic translation initiation factor 4E transporter OS=Homo sapiens OX=9606 GN=EIF4ENIF1 PE=1 SV=2 9.7 3246.1 - 1.25E+06 - - - 1.1866 - 3.56 0.616 - 203.7 1 2 1 0.002 16 0 0 0 4.55E+07 3.81E+07 - - - 8.6653 1 221125_WJC_METTL3_EV_vs_WT_F07.20108.20108.4 3.73E-12 29/186 R.NPEMQFK[136.11]PNTPETVEASAVSGK[136.11]PPNGFSAIYK[136.11].T "sp|Q6W2J9|BCOR_HUMAN,tr|H7BZ37|H7BZ37_HUMAN,tr|H7C2V9|H7C2V9_HUMAN,tr|A0A5F9ZGX7|A0A5F9ZGX7_HUMAN,tr|H7BYY2|H7BYY2_HUMAN,tr|H7C231|H7C231_HUMAN" 6 3458.7243 13.16 105749 20108 4 3458.729932 865.6883 BCL-6 corepressor OS=Homo sapiens OX=9606 GN=BCOR PE=1 SV=1 6.23 3246.5 - 1.20E+06 - - - 1.6408 - 4.731 0.576 - 246.3 1 2 0 0.0057 32 0 0 0 3.56E+08 2.70E+07 - - - 4.7072 1 221125_WJC_METTL3_EV_vs_WT_F07.20116.20116.4 1.92E-12 29/144 R.LGATIEHISVSPAGDLFC[160.03]TSHSDNK.L sp|Q8IWA0|WDR75_HUMAN 1 2655.2599 1.36 105755 20116 4 2655.26357 664.8222 WD repeat-containing protein 75 OS=Homo sapiens OX=9606 GN=WDR75 PE=1 SV=1 5.21 3247.6 - 2.09E+06 - - - 1.3897 - 4.765 0.678 - 613 1 2 0 0.0037 25 0 0 0 3.17E+07 2.34E+07 - - - 5.623 0.9998 221125_WJC_METTL3_EV_vs_WT_F07.20123.20123.2 0.000188 18-Oct K.FAAQELIEVK[136.11].R "sp|Q86U44|MTA70_HUMAN,tr|F5H6D8|F5H6D8_HUMAN,tr|H0YFV6|H0YFV6_HUMAN,tr|B4DTN4|B4DTN4_HUMAN" 4 1154.6427 0.01 105760 20123 2 1154.644193 578.3286 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 4.53 3248.5 - 5.30E+06 - - - 1.3147 - 2.079 0.472 - 270.5 1 2 0 0.0015 10 0 0 0 4.91E+06 3.29E+08 - - - 4.5696 1 221125_WJC_METTL3_EV_vs_WT_F07.20124.20124.3 4.16E-14 21/96 K.GDAEKPEEELEEDDDEELDETLSER.L sp|Q9NS69|TOM22_HUMAN 1 2920.2105 1.6 105761 20124 3 2920.212452 974.4108 Mitochondrial import receptor subunit TOM22 homolog OS=Homo sapiens OX=9606 GN=TOMM22 PE=1 SV=3 3.59 3248.6 - 574833 - - - 0.6595 - 4.169 0.782 - 480.7 1 2 0 0.0019 25 0 0 0 2.86E+07 1.79E+07 - - - 10.5426 0.9999 221125_WJC_METTL3_EV_vs_WT_F07.20131.20131.4 5.10E-07 18/108 K.NTK[136.11]EPPLSLTIHLTSPVVR[166.11].E "sp|Q12906|ILF3_HUMAN,tr|K7EQR9|K7EQR9_HUMAN,tr|K7EKY0|K7EKY0_HUMAN,tr|K7EPG3|K7EPG3_HUMAN,tr|K7EKJ9|K7EKJ9_HUMAN" 5 2119.212 0.89 105766 20131 4 2119.214584 530.8103 Interleukin enhancer-binding factor 3 OS=Homo sapiens OX=9606 GN=ILF3 PE=1 SV=3 8.75 3249.5 - 404247 - - - 1.2151 - 3.282 0.536 - 285.3 1 2 1 0.0026 19 0 0 0 5.40E+06 6.09E+06 - - - 4.2927 0.9999 221125_WJC_METTL3_EV_vs_WT_F07.20132.20132.4 3.38E-07 13/84 K.AQNDLIWNIK[136.11]DELK[136.11]K[136.11].V "sp|P09874|PARP1_HUMAN,tr|A0A7I2V5E9|A0A7I2V5E9_HUMAN,tr|A0A7I2V625|A0A7I2V625_HUMAN,tr|A0A7I2V3E1|A0A7I2V3E1_HUMAN" 4 1851.0316 0.95 105767 20132 4 1851.034566 463.7652 Poly [ADP-ribose] polymerase 1 OS=Homo sapiens OX=9606 GN=PARP1 PE=1 SV=4 6.16 3249.7 - 261443 - - - 1.5764 - 2.548 0.602 - 153.4 1 2 1 0.0029 15 0 0 0 2.53E+07 2.66E+07 - - - 4.7997 1 221125_WJC_METTL3_EV_vs_WT_F07.20134.20134.4 1.26E-06 17/78 K.HTTSIFDDFAHYEK[136.11].R "sp|Q9BYJ9|YTHD1_HUMAN,sp|Q7Z739|YTHD3_HUMAN,tr|A0A087X0Q1|A0A087X0Q1_HUMAN,tr|A0A024R7W5|A0A024R7W5_HUMAN,tr|A0A087WY31|A0A087WY31_HUMAN" 5 1717.7828 1.45 105769 20134 4 1717.783584 430.453 YTH domain-containing family protein 1 OS=Homo sapiens OX=9606 GN=YTHDF1 PE=1 SV=1 5.21 3249.9 - 265658 - - - 0.4855 - 2.936 0.627 - 153.3 1 2 0 0.0008 14 0 0 0 1.01E+08 6.97E+07 - - - 5.0752 1 221125_WJC_METTL3_EV_vs_WT_F07.20139.20139.3 5.97E-08 17/88 K.EIETYHNLLEGGQEDFESSGAGK.L "sp|P35527|K1C9_HUMAN,tr|K7EQQ3|K7EQQ3_HUMAN" 2 2509.1245 999 105773 20139 3 2509.11933 837.3821 "Keratin, type I cytoskeletal 9 OS=Homo sapiens OX=9606 GN=KRT9 PE=1 SV=3" 4.14 3250.7 - 1.13E+06 - - - -2.0573 - 3.628 0.624 - 379.4 1 2 0 -0.0052 23 0 0 0 9.52E+07 0.00E+00 - - - 8.5187 1 221125_WJC_METTL3_EV_vs_WT_F07.20141.20141.3 8.11E-12 20/52 K.HTTSIFDDFAHYEK.R "sp|Q9BYJ9|YTHD1_HUMAN,sp|Q7Z739|YTHD3_HUMAN,tr|A0A087X0Q1|A0A087X0Q1_HUMAN,tr|A0A024R7W5|A0A024R7W5_HUMAN,tr|A0A087WY31|A0A087WY31_HUMAN" 5 1709.7686 1.45 105774 20141 3 1709.771255 570.9301 YTH domain-containing family protein 1 OS=Homo sapiens OX=9606 GN=YTHDF1 PE=1 SV=1 5.21 3250.9 - 2.53E+06 - - - 1.5821 - 3.557 0.648 - 418.9 1 2 0 0.0027 14 0 0 0 3.94E+08 2.72E+08 - - - 9.136 1 221125_WJC_METTL3_EV_vs_WT_F07.20144.20144.4 1.72E-07 17/78 K.HTTSIFDDFAHYEK.R "sp|Q9BYJ9|YTHD1_HUMAN,sp|Q7Z739|YTHD3_HUMAN,tr|A0A087X0Q1|A0A087X0Q1_HUMAN,tr|A0A024R7W5|A0A024R7W5_HUMAN,tr|A0A087WY31|A0A087WY31_HUMAN" 5 1709.7686 1.45 105777 20144 4 1709.770535 428.4494 YTH domain-containing family protein 1 OS=Homo sapiens OX=9606 GN=YTHDF1 PE=1 SV=1 5.21 3251.2 - 786711 - - - 1.161 - 3.037 0.602 - 162.8 1 2 0 0.002 14 0 0 0 1.01E+08 6.97E+07 - - - 4.8696 0.9999 221125_WJC_METTL3_EV_vs_WT_F07.20150.20150.4 2.64E-08 20/84 K.AQNDLIWNIKDELKK.V "sp|P09874|PARP1_HUMAN,tr|A0A7I2V5E9|A0A7I2V5E9_HUMAN,tr|A0A7I2V625|A0A7I2V625_HUMAN,tr|A0A7I2V3E1|A0A7I2V3E1_HUMAN" 4 1826.989 0.95 105781 20150 4 1826.989649 457.7545 Poly [ADP-ribose] polymerase 1 OS=Homo sapiens OX=9606 GN=PARP1 PE=1 SV=4 6.16 3252 - 1.08E+06 - - - 0.329 - 3.246 0.556 - 398.9 1 2 1 0.0006 15 0 0 0 2.53E+07 2.66E+07 - - - 4.4866 1 221125_WJC_METTL3_EV_vs_WT_F07.20151.20151.3 6.88E-09 34/108 K.AAPTPTPAPVPVPVPLPAPAPAPHGEAR.L sp|Q96T58|MINT_HUMAN 1 2674.4595 1.95 105782 20151 3 2674.458853 892.4938 Msx2-interacting protein OS=Homo sapiens OX=9606 GN=SPEN PE=1 SV=1 6.79 3252.1 - 1.07E+06 - - - -0.2445 - 4.668 0.635 - 791.7 1 2 0 -0.0007 28 0 0 0 8.58E+07 4.40E+07 - - - 9.1641 1 221125_WJC_METTL3_EV_vs_WT_F07.20152.20152.3 5.26E-13 19/52 K.HTTSIFDDFAHYEK[136.11].R "sp|Q9BYJ9|YTHD1_HUMAN,sp|Q7Z739|YTHD3_HUMAN,tr|A0A087X0Q1|A0A087X0Q1_HUMAN,tr|A0A024R7W5|A0A024R7W5_HUMAN,tr|A0A087WY31|A0A087WY31_HUMAN" 5 1717.7828 1.45 105783 20152 3 1717.786268 573.6015 YTH domain-containing family protein 1 OS=Homo sapiens OX=9606 GN=YTHDF1 PE=1 SV=1 5.21 3252.2 - 4.78E+06 - - - 2.048 - 3.469 0.654 - 296.1 1 2 0 0.0035 14 0 0 0 3.94E+08 2.72E+08 - - - 9.1361 0.9999 221125_WJC_METTL3_EV_vs_WT_F07.20154.20154.3 1.84E-08 19/88 K.SSSSQVVGPVQEEEYVAEK[136.11]LPSR[166.11].F "sp|Q92667|AKAP1_HUMAN,tr|I3L0W0|I3L0W0_HUMAN" 2 2522.2619 0.98 105785 20154 3 2522.266703 841.7613 "A-kinase anchor protein 1, mitochondrial OS=Homo sapiens OX=9606 GN=AKAP1 PE=1 SV=1" 4.49 3252.4 - 617810 - - - 1.8916 - 3.633 0.597 - 433.2 1 2 1 0.0048 23 0 0 0 1.73E+07 1.77E+07 - - - 8.221 0.9929 221125_WJC_METTL3_EV_vs_WT_F07.20156.20156.2 2.41E-07 30-Nov A.STSSHNLQSIFNIGSR[166.11].G "sp|P43243|MATR3_HUMAN,tr|A8MXP9|A8MXP9_HUMAN,tr|D6R991|D6R991_HUMAN,tr|D6REK4|D6REK4_HUMAN,tr|A0A0R4J2E8|A0A0R4J2E8_HUMAN,tr|D6RCM3|D6RCM3_HUMAN,tr|D6R8Z5|D6R8Z5_HUMAN,tr|D6REM6|D6REM6_HUMAN" 8 1756.8732 0.74 105787 20156 2 1756.874108 879.4439 Matrin-3 OS=Homo sapiens OX=9606 GN=MATR3 PE=1 SV=2 9.49 3252.7 - 324061 - - - 0.5276 - 2.379 0.528 - 365.7 1 1 0 0.0009 16 0 0 0 7.84E+06 1.05E+07 - - - 5.0713 0.9696 221125_WJC_METTL3_EV_vs_WT_F07.20157.20157.2 0.0164 14-Aug F.DDFAHYEK.R "sp|Q9BYJ9|YTHD1_HUMAN,sp|Q7Z739|YTHD3_HUMAN,tr|A0A087X0Q1|A0A087X0Q1_HUMAN,tr|A0A024R7W5|A0A024R7W5_HUMAN,tr|A0A087WY31|A0A087WY31_HUMAN" 5 1023.4298 1.72 105788 20157 2 1023.431359 512.7222 YTH domain-containing family protein 1 OS=Homo sapiens OX=9606 GN=YTHDF1 PE=1 SV=1 4.54 3252.8 - 145973 - - - 1.5477 - 1.54 0.44 - 186.2 1 1 0 0.0016 8 0 0 0 9.45E+06 5.49E+06 - - - 3.5926 0.999 221125_WJC_METTL3_EV_vs_WT_F07.20161.20161.3 0.0195 13/60 R.RKGTDVNVFNTILTTR.S sp|P04083|ANXA1_HUMAN 1 1834.0061 7.89 105790 20161 3 1834.007798 612.3426 Annexin A1 OS=Homo sapiens OX=9606 GN=ANXA1 PE=1 SV=2 10.84 3253.4 - 271853 - - - 0.9286 - 2.052 0.376 - 184.1 1 2 1 0.0017 16 0 0 0 1.81E+06 2.29E+05 - - - 4.5759 0.9998 221125_WJC_METTL3_EV_vs_WT_F07.20162.20162.3 0.000124 16/56 K.AQNDLIWNIKDELKK.V "sp|P09874|PARP1_HUMAN,tr|A0A7I2V5E9|A0A7I2V5E9_HUMAN,tr|A0A7I2V625|A0A7I2V625_HUMAN,tr|A0A7I2V3E1|A0A7I2V3E1_HUMAN" 4 1826.989 1.04 105791 20162 3 1826.990587 610.0036 Poly [ADP-ribose] polymerase 1 OS=Homo sapiens OX=9606 GN=PARP1 PE=1 SV=4 6.16 3253.4 - 857410 - - - 0.8424 - 2.847 0.447 - 360.6 1 2 1 0.0015 15 0 0 0 1.22E+07 1.17E+07 - - - 6.2533 0.9998 221125_WJC_METTL3_EV_vs_WT_F07.20164.20164.3 1.17E-10 18/100 R.VGAGDTSDWPTVLSESSTTVAGKPEK.G sp|Q9BUA3|SPNDC_HUMAN 1 2618.2712 3.28 105793 20164 3 2618.284425 873.7643 Spindlin interactor and repressor of chromatin-binding protein OS=Homo sapiens OX=9606 GN=SPINDOC PE=1 SV=3 4.32 3253.7 - 608851 - - - 5.0678 - 3.244 0.636 - 252.2 1 2 0 0.0133 26 0 0 0 3.93E+07 1.20E+07 - - - 8.3345 0.9992 221125_WJC_METTL3_EV_vs_WT_F07.20165.20165.3 3.70E-05 11/128 K.ANDGGLAAGAPAMHMASYGPEPC[160.03]TDNSDSLIAK[136.11].L "sp|O43823|AKAP8_HUMAN,tr|A0A7P0TBC8|A0A7P0TBC8_HUMAN,tr|A0A7P0T893|A0A7P0T893_HUMAN,tr|M0QX51|M0QX51_HUMAN" 4 3296.4628 1.23 105794 20165 3 3297.463245 1099.8282 A-kinase anchor protein 8 OS=Homo sapiens OX=9606 GN=AKAP8 PE=1 SV=1 4.22 3253.8 - 374862 - - - 303.502 - 2.415 0.568 - 64.1 1 2 0 1.0005 33 0 0 0 2.79E+06 2.27E+06 - - - 6.624 1 221125_WJC_METTL3_EV_vs_WT_F07.20167.20167.3 1.53E-05 13/44 R.FATSEELLSHLR.T "sp|Q9H7S9|ZN703_HUMAN,sp|Q96F45|ZN503_HUMAN" 2 1401.7252 1.61 105796 20167 3 1401.724417 468.249 Zinc finger protein 703 OS=Homo sapiens OX=9606 GN=ZNF703 PE=1 SV=1 5.4 3254.1 - 362166 - - - -0.5793 - 2.355 0.474 - 139.9 1 2 0 -0.0008 12 0 0 0 4.32E+06 2.69E+06 - - - 6.1986 1 221125_WJC_METTL3_EV_vs_WT_F07.20170.20170.3 2.62E-08 14/44 R.FATSEELLSHLR[166.11].T "sp|Q9H7S9|ZN703_HUMAN,sp|Q96F45|ZN503_HUMAN" 2 1411.7335 1.61 105799 20170 3 1411.733565 471.5851 Zinc finger protein 703 OS=Homo sapiens OX=9606 GN=ZNF703 PE=1 SV=1 5.4 3254.5 - 151598 - - - 0.0468 - 2.571 0.552 - 187.1 1 2 0 0.0001 12 0 0 0 4.32E+06 2.69E+06 - - - 7.3117 1 221125_WJC_METTL3_EV_vs_WT_F07.20174.20174.4 4.20E-16 28/162 K.AAPTPTPAPVPVPVPLPAPAPAPHGEAR.L sp|Q96T58|MINT_HUMAN 1 2674.4595 2.62 105801 20174 4 2674.463442 669.6222 Msx2-interacting protein OS=Homo sapiens OX=9606 GN=SPEN PE=1 SV=1 6.79 3255 - 651548 - - - 1.4713 - 4.775 0.574 - 400.2 1 2 0 0.0039 28 0 0 0 1.47E+07 5.60E+06 - - - 4.7064 1 221125_WJC_METTL3_EV_vs_WT_F07.20175.20175.3 1.13E-14 35/108 K.AAPTPTPAPVPVPVPLPAPAPAPHGEAR[166.11].L sp|Q96T58|MINT_HUMAN 1 2684.4678 1.95 105802 20175 3 2684.468796 895.8299 Msx2-interacting protein OS=Homo sapiens OX=9606 GN=SPEN PE=1 SV=1 6.79 3255.1 - 1.65E+06 - - - 0.3796 - 5.019 0.711 - 1143.2 1 2 0 0.001 28 0 0 0 8.58E+07 4.40E+07 - - - 10.1781 1 221125_WJC_METTL3_EV_vs_WT_F07.20177.20177.3 4.78E-11 24/84 R.EQQIVIQSSGGLSKDDIENMVK.N "sp|P38646|GRP75_HUMAN,tr|A0A7I2V2S7|A0A7I2V2S7_HUMAN,tr|A0A7I2V2G2|A0A7I2V2G2_HUMAN,tr|H0Y8S0|H0Y8S0_HUMAN,tr|A0A7I2V3F7|A0A7I2V3F7_HUMAN,tr|A0A7I2YQB2|A0A7I2YQB2_HUMAN,tr|D6RCD7|D6RCD7_HUMAN" 7 2417.2108 0.4 105804 20177 3 2417.215 806.7442 "Stress-70 protein, mitochondrial OS=Homo sapiens OX=9606 GN=HSPA9 PE=1 SV=2" 4.32 3255.3 - 924563 - - - 1.7355 - 4.38 0.602 - 503.4 1 2 1 0.0042 22 0 0 0 1.94E+08 4.79E+08 - - - 8.7524 1 221125_WJC_METTL3_EV_vs_WT_F07.20178.20178.2 8.41E-12 17/26 K.HTTSIFDDFAHYEK.R "sp|Q9BYJ9|YTHD1_HUMAN,sp|Q7Z739|YTHD3_HUMAN,tr|A0A087X0Q1|A0A087X0Q1_HUMAN,tr|A0A024R7W5|A0A024R7W5_HUMAN,tr|A0A087WY31|A0A087WY31_HUMAN" 5 1709.7686 3.5 105805 20178 2 1709.766923 855.8916 YTH domain-containing family protein 1 OS=Homo sapiens OX=9606 GN=YTHDF1 PE=1 SV=1 5.21 3255.5 - 712543 - - - -0.9516 - 3.481 0.691 - 808 1 2 0 -0.0016 14 0 0 0 8.95E+06 2.56E+06 - - - 7.2743 0.9869 221125_WJC_METTL3_EV_vs_WT_F07.20182.20182.2 4.20E-06 14-Sep F.DDFAHYEK[136.11].R "sp|Q9BYJ9|YTHD1_HUMAN,sp|Q7Z739|YTHD3_HUMAN,tr|A0A087X0Q1|A0A087X0Q1_HUMAN,tr|A0A024R7W5|A0A024R7W5_HUMAN,tr|A0A087WY31|A0A087WY31_HUMAN" 5 1031.444 1.71 105809 20182 2 1031.443103 516.7293 YTH domain-containing family protein 1 OS=Homo sapiens OX=9606 GN=YTHDF1 PE=1 SV=1 4.54 3255.9 - 375300 - - - -0.8454 - 1.772 0.453 - 273.6 1 1 0 -0.0009 8 0 0 0 9.50E+06 5.54E+06 - - - 4.112 1 221125_WJC_METTL3_EV_vs_WT_F07.20188.20188.4 3.74E-07 14/78 K.KDDEENYLDLFSHK.N sp|Q07666|KHDR1_HUMAN 1 1751.8002 1.03 105813 20188 4 1751.799711 438.9573 "KH domain-containing, RNA-binding, signal transduction-associated protein 1 OS=Homo sapiens OX=9606 GN=KHDRBS1 PE=1 SV=1" 4.43 3256.8 - 629595 - - - -0.3048 - 2.683 0.535 - 178.9 1 2 0 -0.0005 14 0 0 0 1.42E+08 1.37E+08 - - - 4.2417 1 221125_WJC_METTL3_EV_vs_WT_F07.20192.20192.3 4.85E-08 16/52 K.K[136.11]DDEENYLDLFSHK[136.11].N sp|Q07666|KHDR1_HUMAN 1 1767.8286 1 105815 20192 3 1767.828152 590.2835 "KH domain-containing, RNA-binding, signal transduction-associated protein 1 OS=Homo sapiens OX=9606 GN=KHDRBS1 PE=1 SV=1" 4.43 3257.2 - 1.94E+06 - - - -0.2789 - 2.719 0.583 - 327.6 1 2 0 -0.0005 14 0 0 0 2.88E+08 2.88E+08 - - - 7.698 1 221125_WJC_METTL3_EV_vs_WT_F07.20193.20193.3 8.64E-08 20/76 R.K[136.11]AC[160.03]ADATLSQITNNIDPVGR[166.11].L "sp|P62873|GBB1_HUMAN,tr|F6UT28|F6UT28_HUMAN,tr|B1AKQ8|B1AKQ8_HUMAN" 3 2161.0916 0.67 105816 20193 3 2161.090135 721.3712 Guanine nucleotide-binding protein G(I)\G(S)\G(T) subunit beta-1 OS=Homo sapiens OX=9606 GN=GNB1 PE=1 SV=3 5.95 3257.3 - 1.71E+06 - - - -0.6946 - 3.839 0.533 - 357.4 1 2 0 -0.0015 20 0 0 0 1.62E+07 2.41E+07 - - - 7.7455 1 221125_WJC_METTL3_EV_vs_WT_F07.20195.20195.4 1.31E-05 17/78 K.K[136.11]DDEENYLDLFSHK[136.11].N sp|Q07666|KHDR1_HUMAN 1 1767.8286 1.03 105818 20195 4 1767.827659 442.9644 "KH domain-containing, RNA-binding, signal transduction-associated protein 1 OS=Homo sapiens OX=9606 GN=KHDRBS1 PE=1 SV=1" 4.43 3257.5 - 1.24E+06 - - - -0.5577 - 2.565 0.526 - 271.3 1 2 0 -0.001 14 0 0 0 1.42E+08 1.37E+08 - - - 4.1469 1 221125_WJC_METTL3_EV_vs_WT_F07.20202.20202.3 3.56E-09 22/84 R.EQQIVIQSSGGLSK[136.11]DDIENMVK[136.11].N "sp|P38646|GRP75_HUMAN,tr|A0A7I2V2S7|A0A7I2V2S7_HUMAN,tr|A0A7I2V2G2|A0A7I2V2G2_HUMAN,tr|H0Y8S0|H0Y8S0_HUMAN,tr|A0A7I2V3F7|A0A7I2V3F7_HUMAN,tr|A0A7I2YQB2|A0A7I2YQB2_HUMAN,tr|D6RCD7|D6RCD7_HUMAN" 7 2433.2392 0.4 105824 20202 3 2433.236629 812.087 "Stress-70 protein, mitochondrial OS=Homo sapiens OX=9606 GN=HSPA9 PE=1 SV=2" 4.32 3258.4 - 4.73E+07 - - - -1.0587 - 4.102 0.568 - 372.3 1 2 1 -0.0026 22 0 0 0 1.94E+08 4.79E+08 - - - 8.2183 1 221125_WJC_METTL3_EV_vs_WT_F07.20204.20204.3 1.66E-10 17/52 K.KDDEENYLDLFSHK.N sp|Q07666|KHDR1_HUMAN 1 1751.8002 1 105825 20204 3 1751.799497 584.9407 "KH domain-containing, RNA-binding, signal transduction-associated protein 1 OS=Homo sapiens OX=9606 GN=KHDRBS1 PE=1 SV=1" 4.43 3258.6 - 5.58E+06 - - - -0.427 - 3.094 0.605 - 312.6 1 2 0 -0.0007 14 0 0 0 2.88E+08 2.88E+08 - - - 8.2865 0.9984 221125_WJC_METTL3_EV_vs_WT_F07.20207.20207.3 1.78E-08 17/68 K.NQSQGYNQWQQGQFWGQK[136.11].P "sp|Q00839|HNRPU_HUMAN,tr|A0A1W2PPL4|A0A1W2PPL4_HUMAN,tr|Q5RI18|Q5RI18_HUMAN,tr|A0A1W2PP35|A0A1W2PP35_HUMAN,tr|A0A1W2PPH7|A0A1W2PPH7_HUMAN,tr|A0A1X7SBS1|A0A1X7SBS1_HUMAN" 6 2219.0024 1.08 105828 20207 3 2219.001722 740.6747 Heterogeneous nuclear ribonucleoprotein U OS=Homo sapiens OX=9606 GN=HNRNPU PE=1 SV=6 8.59 3258.9 - 1.03E+06 - - - -0.3119 - 2.932 0.562 - 335.6 1 1 0 -0.0007 18 0 0 0 4.42E+07 4.09E+07 - - - 7.4841 0.9711 221125_WJC_METTL3_EV_vs_WT_F07.20208.20208.3 6.07E-07 14/68 K.NQSQGYNQWQQGQFWGQK.P "sp|Q00839|HNRPU_HUMAN,tr|A0A1W2PPL4|A0A1W2PPL4_HUMAN,tr|Q5RI18|Q5RI18_HUMAN,tr|A0A1W2PP35|A0A1W2PP35_HUMAN,tr|A0A1W2PPH7|A0A1W2PPH7_HUMAN,tr|A0A1X7SBS1|A0A1X7SBS1_HUMAN" 6 2210.9882 1.08 105829 20208 3 2210.976734 738.0033 Heterogeneous nuclear ribonucleoprotein U OS=Homo sapiens OX=9606 GN=HNRNPU PE=1 SV=6 8.59 3259 - 785459 - - - -5.1922 - 2.696 0.58 - 183.3 1 1 0 -0.0115 18 0 0 0 4.42E+07 4.09E+07 - - - 7.4729 1 221125_WJC_METTL3_EV_vs_WT_F07.20210.20210.2 0.000113 14/42 R.EQQIVIQSSGGLSK[136.11]DDIENMVK[136.11].N "sp|P38646|GRP75_HUMAN,tr|A0A7I2V2S7|A0A7I2V2S7_HUMAN,tr|A0A7I2V2G2|A0A7I2V2G2_HUMAN,tr|H0Y8S0|H0Y8S0_HUMAN,tr|A0A7I2V3F7|A0A7I2V3F7_HUMAN,tr|A0A7I2YQB2|A0A7I2YQB2_HUMAN,tr|D6RCD7|D6RCD7_HUMAN" 7 2433.2392 0.19 105831 20210 2 2433.231206 1217.6269 "Stress-70 protein, mitochondrial OS=Homo sapiens OX=9606 GN=HSPA9 PE=1 SV=2" 4.32 3259.3 - 439997 - - - -3.2874 - 3.355 0.605 - 360.8 1 2 1 -0.008 22 0 0 0 6.92E+05 3.68E+06 - - - 6.483 1 221125_WJC_METTL3_EV_vs_WT_F07.20225.20225.4 5.46E-14 27/138 K.ENALVQMADGNQAQLAMSHLNGHK.L "sp|P26599|PTBP1_HUMAN,tr|A0A0U1RRM4|A0A0U1RRM4_HUMAN,tr|A6NLN1|A6NLN1_HUMAN,tr|A0A0D9SF20|A0A0D9SF20_HUMAN,tr|A0A7I2V621|A0A7I2V621_HUMAN,tr|K7EK45|K7EK45_HUMAN" 6 2576.2224 1.06 105842 20225 4 2576.223086 645.0629 Polypyrimidine tract-binding protein 1 OS=Homo sapiens OX=9606 GN=PTBP1 PE=1 SV=1 6 3261 - 1.52E+06 - - - 0.2706 - 5.043 0.647 - 654.7 1 2 0 0.0007 24 0 0 0 4.53E+08 4.27E+08 - - - 5.3766 1 221125_WJC_METTL3_EV_vs_WT_F07.20230.20230.2 1.38E-11 13/34 K.NQSQGYNQWQQGQFWGQK[136.11].P "sp|Q00839|HNRPU_HUMAN,tr|A0A1W2PPL4|A0A1W2PPL4_HUMAN,tr|Q5RI18|Q5RI18_HUMAN,tr|A0A1W2PP35|A0A1W2PP35_HUMAN,tr|A0A1W2PPH7|A0A1W2PPH7_HUMAN,tr|A0A1X7SBS1|A0A1X7SBS1_HUMAN" 6 2219.0024 1.41 105847 20230 2 2219.001022 1110.5085 Heterogeneous nuclear ribonucleoprotein U OS=Homo sapiens OX=9606 GN=HNRNPU PE=1 SV=6 8.59 3261.6 - 452210 - - - -0.6273 - 3.035 0.7 - 559.5 1 1 0 -0.0014 18 0 0 0 7.03E+06 4.99E+06 - - - 6.9403 1 221125_WJC_METTL3_EV_vs_WT_F07.20241.20241.4 2.13E-10 16/174 H.QVVSSDFNSDTHSSTFDAGAGIALNDHFVK[136.11].L "sp|P04406|G3P_HUMAN,tr|E7EUT5|E7EUT5_HUMAN" 2 3173.4781 1.26 105854 20241 4 3173.477511 794.3768 Glyceraldehyde-3-phosphate dehydrogenase OS=Homo sapiens OX=9606 GN=GAPDH PE=1 SV=3 4.54 3263.1 - 3.33E+06 - - - -0.1969 - 3.232 0.652 - 122.9 1 1 0 -0.0006 30 0 0 0 8.73E+07 6.94E+07 - - - 5.2598 1 221125_WJC_METTL3_EV_vs_WT_F07.20243.20243.3 7.40E-06 18/68 S.SASTSSHNLQSIFNIGSR.G "sp|P43243|MATR3_HUMAN,tr|A8MXP9|A8MXP9_HUMAN,tr|D6R991|D6R991_HUMAN,tr|D6REK4|D6REK4_HUMAN,tr|A0A0R4J2E8|A0A0R4J2E8_HUMAN,tr|D6RCM3|D6RCM3_HUMAN,tr|D6R8Z5|D6R8Z5_HUMAN,tr|D6REM6|D6REM6_HUMAN" 8 1904.9341 1.44 105856 20243 3 1904.935461 635.9853 Matrin-3 OS=Homo sapiens OX=9606 GN=MATR3 PE=1 SV=2 9.49 3263.2 - 3.48E+06 - - - 0.7391 - 3.546 0.627 - 368.6 1 1 0 0.0014 18 0 0 0 6.19E+07 4.30E+07 - - - 8.6821 1 221125_WJC_METTL3_EV_vs_WT_F07.20249.20249.3 2.66E-12 31/92 K.ENALVQMADGNQAQLAMSHLNGHK.L "sp|P26599|PTBP1_HUMAN,tr|A0A0U1RRM4|A0A0U1RRM4_HUMAN,tr|A6NLN1|A6NLN1_HUMAN,tr|A0A0D9SF20|A0A0D9SF20_HUMAN,tr|A0A7I2V621|A0A7I2V621_HUMAN,tr|K7EK45|K7EK45_HUMAN" 6 2576.2224 1.02 105860 20249 3 2576.225558 859.7481 Polypyrimidine tract-binding protein 1 OS=Homo sapiens OX=9606 GN=PTBP1 PE=1 SV=1 6 3263.9 - 1.28E+06 - - - 1.2301 - 5.222 0.708 - 989.8 1 2 0 0.0032 24 0 0 0 7.34E+07 7.19E+07 - - - 10.2716 1 221125_WJC_METTL3_EV_vs_WT_F07.20250.20250.3 9.18E-12 24/92 K.ENALVQMADGNQAQLAMSHLNGHK[136.11].L "sp|P26599|PTBP1_HUMAN,tr|A0A0U1RRM4|A0A0U1RRM4_HUMAN,tr|A6NLN1|A6NLN1_HUMAN,tr|A0A0D9SF20|A0A0D9SF20_HUMAN,tr|A0A7I2V621|A0A7I2V621_HUMAN,tr|K7EK45|K7EK45_HUMAN" 6 2584.2366 1.02 105861 20250 3 2584.233433 862.4195 Polypyrimidine tract-binding protein 1 OS=Homo sapiens OX=9606 GN=PTBP1 PE=1 SV=1 6 3264.1 - 1.81E+06 - - - -1.2213 - 4.597 0.596 - 642.7 1 2 0 -0.0032 24 0 0 0 7.34E+07 7.19E+07 - - - 8.7268 1 221125_WJC_METTL3_EV_vs_WT_F07.20256.20256.3 3.85E-13 21/100 R.VGAGDTSDWPTVLSESSTTVAGK[136.11]PEK[136.11].G sp|Q9BUA3|SPNDC_HUMAN 1 2634.2996 3 105865 20256 3 2634.297311 879.1071 Spindlin interactor and repressor of chromatin-binding protein OS=Homo sapiens OX=9606 GN=SPINDOC PE=1 SV=3 4.32 3264.9 - 481008 - - - -0.8522 - 3.757 0.735 - 372.8 1 2 0 -0.0022 26 0 0 0 1.07E+08 3.58E+07 - - - 9.7791 0.9999 221125_WJC_METTL3_EV_vs_WT_F07.20257.20257.4 1.63E-05 13/108 R.GLLQDDAHPTLVTYADHSK[136.11].L "sp|Q86U44|MTA70_HUMAN,tr|F5H6D8|F5H6D8_HUMAN,tr|H0YFV6|H0YFV6_HUMAN,tr|B4DTN4|B4DTN4_HUMAN" 4 2088.0367 0.02 105866 20257 4 2088.041124 523.0165 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 5.13 3265 - 372257 - - - 2.1029 - 2.72 0.494 - 180.4 1 2 0 0.0044 19 0 0 0 2.18E+05 1.18E+07 - - - 3.8631 0.999 221125_WJC_METTL3_EV_vs_WT_F07.20260.20260.3 3.44E-09 18/72 L.SSASTSSHNLQSIFNIGSR[166.11].G "sp|P43243|MATR3_HUMAN,tr|A8MXP9|A8MXP9_HUMAN,tr|D6R991|D6R991_HUMAN,tr|D6REK4|D6REK4_HUMAN,tr|A0A0R4J2E8|A0A0R4J2E8_HUMAN,tr|D6RCM3|D6RCM3_HUMAN,tr|D6R8Z5|D6R8Z5_HUMAN,tr|D6REM6|D6REM6_HUMAN" 8 2001.9744 1.42 105867 20260 3 2001.975568 668.3321 Matrin-3 OS=Homo sapiens OX=9606 GN=MATR3 PE=1 SV=2 9.49 3265.5 - 1.80E+06 - - - 0.6079 - 3.537 0.606 - 314.8 1 1 0 0.0012 19 0 0 0 4.28E+07 3.01E+07 - - - 8.3996 1 221125_WJC_METTL3_EV_vs_WT_F07.20262.20262.3 8.92E-14 23/80 K.ADRDESSPYAAMLAAQDVAQR.C "sp|P62263|RS14_HUMAN,tr|A0A2R8Y811|A0A2R8Y811_HUMAN,tr|E5RH77|E5RH77_HUMAN" 3 2264.0492 1.39 105869 20262 3 2264.049012 755.6903 40S ribosomal protein S14 OS=Homo sapiens OX=9606 GN=RPS14 PE=1 SV=3 4.23 3265.7 - 748197 - - - -0.0649 - 4.38 0.59 - 811.4 1 2 1 -0.0001 21 0 0 0 1.87E+08 1.34E+08 - - - 8.659 1 221125_WJC_METTL3_EV_vs_WT_F07.20270.20270.3 1.40E-11 29/80 K.ADR[166.11]DESSPYAAMLAAQDVAQR[166.11].C "sp|P62263|RS14_HUMAN,tr|A0A2R8Y811|A0A2R8Y811_HUMAN,tr|E5RH77|E5RH77_HUMAN" 3 2284.0657 1.43 105875 20270 3 2284.066666 762.3625 40S ribosomal protein S14 OS=Homo sapiens OX=9606 GN=RPS14 PE=1 SV=3 4.23 3266.6 - 1.08E+06 - - - 0.4234 - 4.805 0.696 - 1252.6 1 2 1 0.001 21 0 0 0 1.87E+08 1.31E+08 - - - 10.0626 0.9957 221125_WJC_METTL3_EV_vs_WT_F07.20272.20272.4 0.00344 15/126 K.RVIISAPSADAPMFVMGVNHEK.Y "sp|P04406|G3P_HUMAN,tr|E7EUT5|E7EUT5_HUMAN" 2 2368.2032 0.92 105877 20272 4 2368.220967 593.0581 Glyceraldehyde-3-phosphate dehydrogenase OS=Homo sapiens OX=9606 GN=GAPDH PE=1 SV=3 6.75 3266.9 - 452182 - - - 7.5205 - 2.546 0.446 - 147.3 1 2 0 0.0178 22 0 0 0 1.66E+07 1.81E+07 - - - 3.4088 1 221125_WJC_METTL3_EV_vs_WT_F07.20277.20277.3 8.96E-12 23/72 L.SSASTSSHNLQSIFNIGSR.G "sp|P43243|MATR3_HUMAN,tr|A8MXP9|A8MXP9_HUMAN,tr|D6R991|D6R991_HUMAN,tr|D6REK4|D6REK4_HUMAN,tr|A0A0R4J2E8|A0A0R4J2E8_HUMAN,tr|D6RCM3|D6RCM3_HUMAN,tr|D6R8Z5|D6R8Z5_HUMAN,tr|D6REM6|D6REM6_HUMAN" 8 1991.9661 1.42 105880 20277 3 1991.969112 664.996 Matrin-3 OS=Homo sapiens OX=9606 GN=MATR3 PE=1 SV=2 9.49 3267.4 - 2.47E+06 - - - 1.5216 - 3.595 0.687 - 651.1 1 1 0 0.003 19 0 0 0 4.29E+07 3.01E+07 - - - 9.3421 0.9999 221125_WJC_METTL3_EV_vs_WT_F07.20310.20310.4 5.11E-11 18/120 R.TNAENEFVTIKKDVDGAYMTK.V sp|P04264|K2C1_HUMAN 1 2373.1522 17.16 105905 20310 4 2373.154651 594.2953 "Keratin, type II cytoskeletal 1 OS=Homo sapiens OX=9606 GN=KRT1 PE=1 SV=6" 4.78 3271.8 - 1.12E+06 - - - 1.0214 - 3.745 0.556 - 183.9 1 2 1 0.0024 21 0 0 0 2.06E+07 1.20E+06 - - - 4.5013 0.9999 221125_WJC_METTL3_EV_vs_WT_F07.20311.20311.4 6.03E-06 19/102 R.HLQLAIR[166.11]NDEELNK[136.11]LLGK[136.11].V "sp|Q9BTM1|H2AJ_HUMAN,sp|Q99878|H2A1J_HUMAN,sp|Q16777|H2A2C_HUMAN,sp|P20671|H2A1D_HUMAN,sp|P0C0S8|H2A1_HUMAN,sp|Q6FI13|H2A2A_HUMAN,sp|Q96KK5|H2A1H_HUMAN,tr|A0A0U1RR32|A0A0U1RR32_HUMAN,tr|A0A0U1RRH7|A0A0U1RRH7_HUMAN,tr|H0YFX9|H0YFX9_HUMAN" 10 2129.2167 1.07 105906 20311 4 2129.217832 533.3115 Histone H2A.J OS=Homo sapiens OX=9606 GN=H2AJ PE=1 SV=1 6.76 3271.9 - 606683 - - - 0.5284 - 2.591 0.505 - 196.7 1 2 2 0.0011 18 0 0 0 2.49E+07 2.33E+07 - - - 3.9473 1 221125_WJC_METTL3_EV_vs_WT_F07.20312.20312.4 2.12E-11 19/162 K.RVIISAPSADAPMFVMGVNHEKYDNSLK.L "sp|P04406|G3P_HUMAN,tr|E7EUT5|E7EUT5_HUMAN" 2 3088.5474 0.74 105907 20312 4 3088.555686 773.1441 Glyceraldehyde-3-phosphate dehydrogenase OS=Homo sapiens OX=9606 GN=GAPDH PE=1 SV=3 6.75 3272 - 443042 - - - 2.6789 - 3.341 0.656 - 138.2 1 2 1 0.0083 28 0 0 0 8.74E+06 1.18E+07 - - - 5.3081 1 221125_WJC_METTL3_EV_vs_WT_F07.20315.20315.4 2.06E-07 20/186 K.VGGTNLGAPGAFGQSPFSQPPAPPHQNTFPPR.S sp|Q96I24|FUBP3_HUMAN 1 3227.5901 2.86 105908 20315 4 3227.591945 807.9048 Far upstream element-binding protein 3 OS=Homo sapiens OX=9606 GN=FUBP3 PE=1 SV=2 9.73 3272.4 - 465118 - - - 0.5778 - 3.62 0.53 - 110.2 1 2 0 0.0019 32 0 0 0 1.25E+08 4.36E+07 - - - 4.227 1 221125_WJC_METTL3_EV_vs_WT_F07.20317.20317.4 1.44E-08 23/138 K.DVIGIAHHPHQNLIATYSEDGLLK.L sp|Q2TAY7|SMU1_HUMAN 1 2640.366 1.01 105909 20317 4 2640.371894 661.0988 WD40 repeat-containing protein SMU1 OS=Homo sapiens OX=9606 GN=SMU1 PE=1 SV=2 5.73 3272.6 - 673819 - - - 2.2323 - 3.979 0.545 - 408 1 2 0 0.0059 24 0 0 0 1.78E+07 1.76E+07 - - - 4.4113 0.9999 221125_WJC_METTL3_EV_vs_WT_F07.20319.20319.4 7.88E-09 18/120 K.ADR[166.11]DESSPYAAMLAAQDVAQR[166.11].C "sp|P62263|RS14_HUMAN,tr|A0A2R8Y811|A0A2R8Y811_HUMAN,tr|E5RH77|E5RH77_HUMAN" 3 2284.0657 0.74 105911 20319 4 2284.066192 572.0237 40S ribosomal protein S14 OS=Homo sapiens OX=9606 GN=RPS14 PE=1 SV=3 4.23 3272.9 - 572110 - - - 0.2158 - 2.945 0.58 - 164.7 1 2 1 0.0005 21 0 0 0 9.50E+06 1.29E+07 - - - 4.6313 1 221125_WJC_METTL3_EV_vs_WT_F07.20320.20320.4 7.35E-12 22/120 K.ADRDESSPYAAMLAAQDVAQR.C "sp|P62263|RS14_HUMAN,tr|A0A2R8Y811|A0A2R8Y811_HUMAN,tr|E5RH77|E5RH77_HUMAN" 3 2264.0492 0.75 105912 20320 4 2264.048738 567.0196 40S ribosomal protein S14 OS=Homo sapiens OX=9606 GN=RPS14 PE=1 SV=3 4.23 3273 - 495550 - - - -0.186 - 3.97 0.646 - 525.6 1 2 1 -0.0004 21 0 0 0 9.50E+06 1.27E+07 - - - 5.3045 0.9999 221125_WJC_METTL3_EV_vs_WT_F07.20324.20324.4 1.90E-09 20/114 K.HYFQNTQGLIFVVDSNDR[166.11]ER[166.11].L "sp|P18085|ARF4_HUMAN,sp|P84077|ARF1_HUMAN,sp|P61204|ARF3_HUMAN,sp|P84085|ARF5_HUMAN,tr|F5H423|F5H423_HUMAN,tr|C9J1Z8|C9J1Z8_HUMAN,tr|C9JPM4|C9JPM4_HUMAN,tr|C9JAK5|C9JAK5_HUMAN,tr|F5H0C7|F5H0C7_HUMAN" 9 2457.194 1.18 105914 20324 4 2457.191871 615.3058 ADP-ribosylation factor 4 OS=Homo sapiens OX=9606 GN=ARF4 PE=1 SV=3 5.38 3273.5 - 633218 - - - -0.8709 - 3.542 0.602 - 324.8 1 2 1 -0.0021 20 0 0 0 1.39E+08 1.18E+08 - - - 4.888 1 221125_WJC_METTL3_EV_vs_WT_F07.20328.20328.4 6.80E-08 21/144 S.DFNSDTHSSTFDAGAGIALNDHFVK[136.11].L "sp|P04406|G3P_HUMAN,tr|E7EUT5|E7EUT5_HUMAN" 2 2673.2187 0.99 105916 20328 4 2673.220357 669.3119 Glyceraldehyde-3-phosphate dehydrogenase OS=Homo sapiens OX=9606 GN=GAPDH PE=1 SV=3 4.54 3274.1 - 1.25E+06 - - - 0.6296 - 3.175 0.631 - 130.6 1 1 0 0.0017 25 0 0 0 4.44E+07 4.51E+07 - - - 5.0853 0.9999 221125_WJC_METTL3_EV_vs_WT_F07.20330.20330.3 4.10E-08 21/76 K.HYFQNTQGLIFVVDSNDR[166.11]ER[166.11].L "sp|P18085|ARF4_HUMAN,sp|P84077|ARF1_HUMAN,sp|P61204|ARF3_HUMAN,sp|P84085|ARF5_HUMAN,tr|F5H423|F5H423_HUMAN,tr|C9J1Z8|C9J1Z8_HUMAN,tr|C9JPM4|C9JPM4_HUMAN,tr|C9JAK5|C9JAK5_HUMAN,tr|F5H0C7|F5H0C7_HUMAN" 9 2457.194 1.23 105917 20330 3 2457.198981 820.0719 ADP-ribosylation factor 4 OS=Homo sapiens OX=9606 GN=ARF4 PE=1 SV=3 5.38 3274.3 - 997645 - - - 2.0226 - 3.399 0.576 - 352.3 1 2 1 0.005 20 0 0 0 1.30E+08 1.06E+08 - - - 7.9286 1 221125_WJC_METTL3_EV_vs_WT_F07.20333.20333.3 2.50E-13 26/76 K.HYFQNTQGLIFVVDSNDRER.L "sp|P18085|ARF4_HUMAN,sp|P84077|ARF1_HUMAN,sp|P61204|ARF3_HUMAN,sp|P84085|ARF5_HUMAN,tr|F5H423|F5H423_HUMAN,tr|C9J1Z8|C9J1Z8_HUMAN,tr|C9JPM4|C9JPM4_HUMAN,tr|C9JAK5|C9JAK5_HUMAN,tr|F5H0C7|F5H0C7_HUMAN" 9 2437.1775 1.22 105920 20333 3 2437.180253 813.3998 ADP-ribosylation factor 4 OS=Homo sapiens OX=9606 GN=ARF4 PE=1 SV=3 5.38 3274.7 - 625608 - - - 1.1415 - 4.156 0.695 - 750.8 1 2 1 0.0028 20 0 0 0 1.31E+08 1.07E+08 - - - 9.7438 1 221125_WJC_METTL3_EV_vs_WT_F07.20334.20334.4 3.25E-10 22/156 R.IKEETEIIEGEVVEIQIDRPATGTGSK.V "sp|Q9Y230|RUVB2_HUMAN,tr|M0R0Y3|M0R0Y3_HUMAN,tr|X6R2L4|X6R2L4_HUMAN" 3 2940.5292 1.43 105921 20334 4 2940.540446 736.1396 RuvB-like 2 OS=Homo sapiens OX=9606 GN=RUVBL2 PE=1 SV=3 4.31 3274.8 - 470536 - - - 3.8374 - 4.439 0.642 - 279.1 1 2 1 0.0113 27 0 0 0 7.01E+06 4.91E+06 - - - 5.2772 0.9999 221125_WJC_METTL3_EV_vs_WT_F07.20335.20335.4 0.000183 10/102 R.SPSELFAQHIVTIVHHVK.E "sp|Q9Y2W1|TR150_HUMAN,tr|A0A3B3ITZ9|A0A3B3ITZ9_HUMAN" 2 2041.1109 2.77 105922 20335 4 2041.112154 511.285 Thyroid hormone receptor-associated protein 3 OS=Homo sapiens OX=9606 GN=THRAP3 PE=1 SV=2 6.78 3274.9 - 184722 - - - 0.6168 - 2.1 0.409 - 68.9 1 2 0 0.0013 18 0 0 0 5.10E+06 1.84E+06 - - - 3.0397 0.9999 221125_WJC_METTL3_EV_vs_WT_F07.20338.20338.4 8.88E-06 27/114 K.HYFQNTQGLIFVVDSNDRER.L "sp|P18085|ARF4_HUMAN,sp|P84077|ARF1_HUMAN,sp|P61204|ARF3_HUMAN,sp|P84085|ARF5_HUMAN,tr|F5H423|F5H423_HUMAN,tr|C9J1Z8|C9J1Z8_HUMAN,tr|C9JPM4|C9JPM4_HUMAN,tr|C9JAK5|C9JAK5_HUMAN,tr|F5H0C7|F5H0C7_HUMAN" 9 2437.1775 1.17 105923 20338 4 2437.182899 610.3016 ADP-ribosylation factor 4 OS=Homo sapiens OX=9606 GN=ARF4 PE=1 SV=3 5.38 3275.4 - 1.47E+06 - - - 2.2272 - 4.682 0.601 - 677.5 1 2 1 0.0054 20 0 0 0 1.38E+08 1.18E+08 - - - 4.9717 1 221125_WJC_METTL3_EV_vs_WT_F07.20340.20340.4 1.34E-10 27/132 R.HFLLEEDK[136.11]PEEPTAHAFVSTLTR[166.11].G "sp|P49327|FAS_HUMAN,tr|A0A0U1RQF0|A0A0U1RQF0_HUMAN" 2 2684.3565 0.68 105925 20340 4 2684.363816 672.0964 Fatty acid synthase OS=Homo sapiens OX=9606 GN=FASN PE=1 SV=3 4.92 3275.7 - 895673 - - - 2.725 - 4.411 0.602 - 561.4 1 2 0 0.0073 23 0 0 0 5.85E+07 8.64E+07 - - - 4.9446 0.9999 221125_WJC_METTL3_EV_vs_WT_F07.20341.20341.4 8.15E-09 18/138 K.DVIGIAHHPHQNLIATYSEDGLLK[136.11].L sp|Q2TAY7|SMU1_HUMAN 1 2648.3802 1.02 105926 20341 4 2648.386624 663.1023 WD40 repeat-containing protein SMU1 OS=Homo sapiens OX=9606 GN=SMU1 PE=1 SV=2 5.73 3275.8 - 608076 - - - 2.4256 - 3.219 0.533 - 229 1 2 0 0.0064 24 0 0 0 1.77E+07 1.74E+07 - - - 4.2387 1 221125_WJC_METTL3_EV_vs_WT_F07.20342.20342.3 3.50E-09 20/124 K.VGGTNLGAPGAFGQSPFSQPPAPPHQNTFPPR.S sp|Q96I24|FUBP3_HUMAN 1 3227.5901 2.58 105927 20342 3 3227.595103 1076.8706 Far upstream element-binding protein 3 OS=Homo sapiens OX=9606 GN=FUBP3 PE=1 SV=2 9.73 3275.9 - 488082 - - - 1.5563 - 3.952 0.65 - 204.3 1 2 0 0.005 32 0 0 0 4.15E+07 1.61E+07 - - - 8.9471 1 221125_WJC_METTL3_EV_vs_WT_F07.20343.20343.4 3.42E-09 23/186 K.VGGTNLGAPGAFGQSPFSQPPAPPHQNTFPPR[166.11].S sp|Q96I24|FUBP3_HUMAN 1 3237.5984 3.08 105928 20343 4 3237.601175 810.4069 Far upstream element-binding protein 3 OS=Homo sapiens OX=9606 GN=FUBP3 PE=1 SV=2 9.73 3276.1 - 387651 - - - 0.8726 - 3.757 0.526 - 167.6 1 2 0 0.0028 32 0 0 0 5.66E+07 1.84E+07 - - - 4.2032 1 221125_WJC_METTL3_EV_vs_WT_F07.20345.20345.4 2.44E-09 22/102 R.HLQLAIRNDEELNKLLGK.V "sp|Q9BTM1|H2AJ_HUMAN,sp|Q99878|H2A1J_HUMAN,sp|Q16777|H2A2C_HUMAN,sp|P20671|H2A1D_HUMAN,sp|P0C0S8|H2A1_HUMAN,sp|Q6FI13|H2A2A_HUMAN,sp|Q96KK5|H2A1H_HUMAN,tr|A0A0U1RR32|A0A0U1RR32_HUMAN,tr|A0A0U1RRH7|A0A0U1RRH7_HUMAN,tr|H0YFX9|H0YFX9_HUMAN" 10 2103.18 1.07 105929 20345 4 2103.18466 526.8023 Histone H2A.J OS=Homo sapiens OX=9606 GN=H2AJ PE=1 SV=1 6.76 3276.3 - 1.01E+06 - - - 2.1981 - 3.795 0.634 - 457.5 1 2 2 0.0046 18 0 0 0 2.48E+07 2.31E+07 - - - 5.1999 1 221125_WJC_METTL3_EV_vs_WT_F07.20349.20349.3 0.000123 Dec-84 K.DPSSGQEVATPPVPQLQVC[160.03]EPK.E "sp|Q9UKV3|ACINU_HUMAN,tr|S4R3H4|S4R3H4_HUMAN,tr|E7EQT4|E7EQT4_HUMAN" 3 2362.1475 1.99 105931 20349 3 2362.147255 788.3898 Apoptotic chromatin condensation inducer in the nucleus OS=Homo sapiens OX=9606 GN=ACIN1 PE=1 SV=2 4.14 3276.7 - 544711 - - - -0.0936 - 2.344 0.498 - 98.1 1 2 0 -0.0002 22 0 0 0 1.06E+07 5.34E+06 - - - 6.1118 1 221125_WJC_METTL3_EV_vs_WT_F07.20354.20354.3 1.01E-08 16/52 R.HAWLYQAEEEFEKR.Q "sp|Q96DF8|ESS2_HUMAN,tr|F8WEF8|F8WEF8_HUMAN" 2 1834.8638 1.48 105936 20354 3 1834.869133 612.6286 Splicing factor ESS-2 homolog OS=Homo sapiens OX=9606 GN=ESS2 PE=1 SV=1 4.91 3277.3 - 383150 - - - 2.8803 - 3.004 0.647 - 389.8 1 2 0 0.0053 14 0 0 0 9.12E+06 6.15E+06 - - - 8.6751 0.9998 221125_WJC_METTL3_EV_vs_WT_F07.20355.20355.3 3.09E-07 Nov-80 K.LK[136.11]ESSHSGVVLSVEEVEAGLK[136.11].G "sp|Q9NRA8|4ET_HUMAN,tr|B1AKL4|B1AKL4_HUMAN,tr|B0QYZ7|B0QYZ7_HUMAN" 3 2212.1922 1.65 105937 20355 3 2212.189447 738.4047 Eukaryotic translation initiation factor 4E transporter OS=Homo sapiens OX=9606 GN=EIF4ENIF1 PE=1 SV=2 4.91 3277.4 - 329838 - - - -1.2345 - 2.808 0.495 - 150.5 1 2 1 -0.0027 21 0 0 0 8.39E+06 5.08E+06 - - - 6.5333 1 221125_WJC_METTL3_EV_vs_WT_F07.20359.20359.4 3.25E-09 28/204 R.SFAHLLPSPEPSPEGSYVGQHSQGLGGHYADSYLK.R "tr|K7EQG2|K7EQG2_HUMAN,tr|E9PAU2|E9PAU2_HUMAN,tr|A0A087WZ13|A0A087WZ13_HUMAN" 3 3711.7594 0.89 105939 20359 4 3711.758214 928.9471 Uncharacterized protein (Fragment) OS=Homo sapiens OX=9606 PE=1 SV=1 5.72 3278 - 460959 - - - -0.3168 - 4.184 0.654 - 277.7 1 2 0 -0.0012 35 0 0 0 1.53E+07 1.71E+07 - - - 5.3424 0.9999 221125_WJC_METTL3_EV_vs_WT_F07.20363.20363.4 0.000362 14/126 R.VSAVDQVSQTISLTR[166.11]PFHNGVK[136.11].C "sp|Q96F86|EDC3_HUMAN,tr|H3BTH0|H3BTH0_HUMAN,tr|H3BPW9|H3BPW9_HUMAN,tr|H3BMB8|H3BMB8_HUMAN,tr|H3BTF8|H3BTF8_HUMAN,tr|H3BQ37|H3BQ37_HUMAN,tr|H3BQP5|H3BQP5_HUMAN,tr|H3BU87|H3BU87_HUMAN,tr|H3BNJ7|H3BNJ7_HUMAN" 9 2400.288 4.56 105941 20363 4 2400.289388 601.0793 Enhancer of mRNA-decapping protein 3 OS=Homo sapiens OX=9606 GN=EDC3 PE=1 SV=1 8.73 3278.5 - 605812 - - - 0.5666 - 3.223 0.432 - 117 1 2 0 0.0014 22 0 0 0 4.91E+07 1.08E+07 - - - 3.3687 0.9236 221125_WJC_METTL3_EV_vs_WT_F07.20366.20366.3 1.75E-06 Dec-84 K.DPSSGQEVATPPVPQLQVC[160.03]EPK[136.11].E "sp|Q9UKV3|ACINU_HUMAN,tr|S4R3H4|S4R3H4_HUMAN,tr|E7EQT4|E7EQT4_HUMAN" 3 2370.1617 2.57 105944 20366 3 2372.168425 791.0612 Apoptotic chromatin condensation inducer in the nucleus OS=Homo sapiens OX=9606 GN=ACIN1 PE=1 SV=2 4.14 3278.9 - 247201 - - - 846.6718 - 2.287 0.469 - 128.3 1 2 0 2.0067 22 0 0 0 1.72E+07 6.67E+06 - - - 5.1743 1 221125_WJC_METTL3_EV_vs_WT_F07.20372.20372.3 4.90E-09 19/92 K.KAFSAVDTDGNGTINAQELGAALK.A sp|Q9NZT1|CALL5_HUMAN 1 2390.2078 112.44 105948 20372 3 2390.212981 797.7432 Calmodulin-like protein 5 OS=Homo sapiens OX=9606 GN=CALML5 PE=1 SV=2 4.56 3279.7 - 469004 - - - 2.181 - 3.696 0.656 - 418.4 1 2 0 0.0052 24 0 0 0 8.64E+06 7.68E+04 - - - 8.8885 0.9998 221125_WJC_METTL3_EV_vs_WT_F07.20374.20374.4 2.61E-06 18/126 R.VSAVDQVSQTISLTRPFHNGVK.C "sp|Q96F86|EDC3_HUMAN,tr|H3BTH0|H3BTH0_HUMAN,tr|H3BPW9|H3BPW9_HUMAN,tr|H3BMB8|H3BMB8_HUMAN,tr|H3BTF8|H3BTF8_HUMAN,tr|H3BQ37|H3BQ37_HUMAN,tr|H3BQP5|H3BQP5_HUMAN,tr|H3BU87|H3BU87_HUMAN,tr|H3BNJ7|H3BNJ7_HUMAN" 9 2382.2656 1 105950 20374 4 2382.273559 596.5737 Enhancer of mRNA-decapping protein 3 OS=Homo sapiens OX=9606 GN=EDC3 PE=1 SV=1 8.73 3280 - 681546 - - - 3.3586 - 3.349 0.463 - 218.9 1 2 0 0.008 22 0 0 0 7.99E+06 8.01E+06 - - - 3.6492 0.9999 221125_WJC_METTL3_EV_vs_WT_F07.20375.20375.4 4.88E-08 17/144 K.ENPSATLEDLEK[136.11]PGVDEEPQHVLLR[166.11].Y sp|Q92900|RENT1_HUMAN 1 2832.426 1.18 105951 20375 4 2832.436772 709.1138 Regulator of nonsense transcripts 1 OS=Homo sapiens OX=9606 GN=UPF1 PE=1 SV=2 4.25 3280.1 - 377642 - - - 3.7897 - 3.573 0.527 - 134.3 1 2 0 0.0107 25 0 0 0 3.46E+07 2.94E+07 - - - 4.2151 1 221125_WJC_METTL3_EV_vs_WT_F07.20379.20379.3 9.84E-13 15/84 K.C[160.03]C[160.03]NIC[160.03]GTSENDDQLLFC[160.03]DDC[160.03]DR.G "sp|Q92785|REQU_HUMAN,tr|J3KMZ8|J3KMZ8_HUMAN" 2 2766.0084 1.65 105953 20379 3 2766.002435 923.0101 Zinc finger protein ubi-d4 OS=Homo sapiens OX=9606 GN=DPF2 PE=1 SV=2 3.61 3280.6 - 448650 - - - -2.1696 - 3.035 0.821 - 228.9 1 2 0 -0.006 22 0 0 0 1.33E+07 8.04E+06 - - - 10.3238 1 221125_WJC_METTL3_EV_vs_WT_F07.20381.20381.4 5.29E-12 25/204 R.SFAHLLPSPEPSPEGSYVGQHSQGLGGHYADSYLK[136.11].R "tr|K7EQG2|K7EQG2_HUMAN,tr|E9PAU2|E9PAU2_HUMAN,tr|A0A087WZ13|A0A087WZ13_HUMAN" 3 3719.7736 0.89 105955 20381 4 3719.787577 930.9507 Uncharacterized protein (Fragment) OS=Homo sapiens OX=9606 PE=1 SV=1 5.72 3280.9 - 503179 - - - 3.7602 - 4.593 0.689 - 214.3 1 2 0 0.014 35 0 0 0 1.53E+07 1.71E+07 - - - 5.6711 0.9999 221125_WJC_METTL3_EV_vs_WT_F07.20382.20382.3 2.85E-05 18/124 K.VGGTNLGAPGAFGQSPFSQPPAPPHQNTFPPR[166.11].S sp|Q96I24|FUBP3_HUMAN 1 3237.5984 2.48 105956 20382 3 3237.607313 1080.2067 Far upstream element-binding protein 3 OS=Homo sapiens OX=9606 GN=FUBP3 PE=1 SV=2 9.73 3281 - 366890 - - - 2.7684 - 2.898 0.561 - 150.6 1 2 0 0.009 32 0 0 0 9.72E+07 3.92E+07 - - - 7.24 1 221125_WJC_METTL3_EV_vs_WT_F07.20383.20383.3 7.65E-12 17/72 R.TSQNSELNNMQDLVEDYKK.K sp|P35908|K22E_HUMAN 1 2255.0376 120.72 105957 20383 3 2255.037611 752.6865 "Keratin, type II cytoskeletal 2 epidermal OS=Homo sapiens OX=9606 GN=KRT2 PE=1 SV=2" 4.32 3281.1 - 356440 - - - 0.0089 - 3.496 0.632 - 441.7 1 2 0 0 19 0 0 0 1.17E+09 9.73E+06 - - - 8.6612 1 221125_WJC_METTL3_EV_vs_WT_F07.20389.20389.4 1.04E-14 33/132 R.HFLLEEDKPEEPTAHAFVSTLTR.G "sp|P49327|FAS_HUMAN,tr|A0A0U1RQF0|A0A0U1RQF0_HUMAN" 2 2666.334 0.67 105961 20389 4 2666.338237 667.5908 Fatty acid synthase OS=Homo sapiens OX=9606 GN=FASN PE=1 SV=3 4.92 3281.9 - 1.38E+06 - - - 1.5774 - 4.724 0.687 - 699.8 1 2 0 0.0042 23 0 0 0 5.76E+07 8.61E+07 - - - 5.7075 1 221125_WJC_METTL3_EV_vs_WT_F07.20390.20390.3 1.83E-13 13/84 K.C[160.03]C[160.03]NIC[160.03]GTSENDDQLLFC[160.03]DDC[160.03]DR[166.11].G "sp|Q92785|REQU_HUMAN,tr|J3KMZ8|J3KMZ8_HUMAN" 2 2776.0167 1.65 105962 20390 3 2776.019733 926.3462 Zinc finger protein ubi-d4 OS=Homo sapiens OX=9606 GN=DPF2 PE=1 SV=2 3.61 3282.1 - 376693 - - - 1.0904 - 2.813 0.855 - 171.4 1 2 0 0.003 22 0 0 0 1.33E+07 8.04E+06 - - - 10.5236 1 221125_WJC_METTL3_EV_vs_WT_F07.20396.20396.4 1.42E-11 20/186 K.IQALPTVPVTEEHVGSGLEC[160.03]PVC[160.03]KDDYALGER.V "sp|Q9BV68|RN126_HUMAN,tr|K7EIY6|K7EIY6_HUMAN" 2 3538.7072 1.86 105965 20396 4 3538.700002 885.6841 E3 ubiquitin-protein ligase RNF126 OS=Homo sapiens OX=9606 GN=RNF126 PE=1 SV=2 4.35 3282.9 - 548088 - - - -2.0397 - 3.555 0.669 - 101.2 1 2 1 -0.0072 32 0 0 0 2.67E+07 1.44E+07 - - - 5.4299 0.9954 221125_WJC_METTL3_EV_vs_WT_F07.20402.20402.2 5.27E-05 30-Oct K.TITLEVEPSDTIENVK.A "sp|P62979|RS27A_HUMAN,sp|P0CG48|UBC_HUMAN,sp|P0CG47|UBB_HUMAN,sp|P62987|RL40_HUMAN,tr|F5H388|F5H388_HUMAN,tr|F5GYU3|F5GYU3_HUMAN,tr|B4DV12|B4DV12_HUMAN,tr|J3QSA3|J3QSA3_HUMAN,tr|Q5PY61|Q5PY61_HUMAN,tr|F5H2Z3|F5H2Z3_HUMAN,tr|J3QS39|J3QS39_HUMAN,tr|J3QTR3|J3QTR3_HUMAN,tr|Q96C32|Q96C32_HUMAN,tr|M0R1V7|M0R1V7_HUMAN,tr|F5H747|F5H747_HUMAN,tr|F5H747|F5H747_HUMAN,tr|F5GXK7|F5GXK7_HUMAN,tr|F5GXK7|F5GXK7_HUMAN,tr|F5H6Q2|F5H6Q2_HUMAN,tr|F5GZ39|F5GZ39_HUMAN,tr|J3QKN0|J3QKN0_HUMAN,tr|J3QKN0|J3QKN0_HUMAN,tr|J3QKN0|J3QKN0_HUMAN,tr|F5H265|F5H265_HUMAN" 24 1786.92 0.42 105968 20402 2 1786.930617 894.4673 Ubiquitin-40S ribosomal protein S27a OS=Homo sapiens OX=9606 GN=RPS27A PE=1 SV=2 4 3283.8 - 229051 - - - 5.9275 - 2.177 0.525 - 255.7 1 2 0 0.0106 16 0 0 0 4.03E+06 9.51E+06 - - - 4.8279 1 221125_WJC_METTL3_EV_vs_WT_F07.20405.20405.3 2.56E-14 40/100 R.VGAGDTSDWPTVLSESSTTVAGKPEK.G sp|Q9BUA3|SPNDC_HUMAN 1 2618.2712 3.25 105970 20405 3 2618.275038 873.7643 Spindlin interactor and repressor of chromatin-binding protein OS=Homo sapiens OX=9606 GN=SPINDOC PE=1 SV=3 4.32 3284.1 - 1.68E+06 - - - 1.4827 - 5.86 0.756 - 2099.4 1 2 0 0.0039 26 0 0 0 1.08E+08 3.34E+07 - - - 11.0355 0.9998 221125_WJC_METTL3_EV_vs_WT_F07.20409.20409.4 0.03 Nov-96 R.DIGTAIQFLHSHNIAHR[166.11].D "sp|Q16644|MAPK3_HUMAN,tr|C9J8E1|C9J8E1_HUMAN" 2 1939.0052 0.43 105972 20409 4 1939.007406 485.7586 MAP kinase-activated protein kinase 3 OS=Homo sapiens OX=9606 GN=MAPKAPK3 PE=1 SV=1 7.02 3284.6 - 119166 - - - 1.1387 - 2.354 0.374 - 63.2 1 2 0 0.0022 17 0 0 0 1.80E+06 4.17E+06 - - - 2.7779 0.972 221125_WJC_METTL3_EV_vs_WT_F07.20417.20417.2 2.05E-05 30-Nov K.TITLEVEPSDTIENVK[136.11].A "sp|P62979|RS27A_HUMAN,sp|P0CG48|UBC_HUMAN,sp|P0CG47|UBB_HUMAN,sp|P62987|RL40_HUMAN,tr|F5H388|F5H388_HUMAN,tr|F5GYU3|F5GYU3_HUMAN,tr|B4DV12|B4DV12_HUMAN,tr|J3QSA3|J3QSA3_HUMAN,tr|Q5PY61|Q5PY61_HUMAN,tr|F5H2Z3|F5H2Z3_HUMAN,tr|J3QS39|J3QS39_HUMAN,tr|J3QTR3|J3QTR3_HUMAN,tr|Q96C32|Q96C32_HUMAN,tr|M0R1V7|M0R1V7_HUMAN,tr|F5H747|F5H747_HUMAN,tr|F5H747|F5H747_HUMAN,tr|F5GXK7|F5GXK7_HUMAN,tr|F5GXK7|F5GXK7_HUMAN,tr|F5H6Q2|F5H6Q2_HUMAN,tr|F5GZ39|F5GZ39_HUMAN,tr|J3QKN0|J3QKN0_HUMAN,tr|J3QKN0|J3QKN0_HUMAN,tr|J3QKN0|J3QKN0_HUMAN,tr|F5H265|F5H265_HUMAN" 24 1794.9342 0.76 105977 20417 2 1795.931702 898.4744 Ubiquitin-40S ribosomal protein S27a OS=Homo sapiens OX=9606 GN=RPS27A PE=1 SV=2 4 3285.6 - 373367 - - - 555.7179 - 2.376 0.528 - 276.4 1 2 0 0.9975 16 0 0 0 4.03E+06 5.28E+06 - - - 4.7553 0.9573 221125_WJC_METTL3_EV_vs_WT_F07.20418.20418.3 0.249 Sep-48 K.K[136.11]YDAFLASESLIK[136.11].Q sp|P62906|RL10A_HUMAN 1 1499.8206 0.91 105978 20418 3 1499.823085 500.9475 60S ribosomal protein L10a OS=Homo sapiens OX=9606 GN=RPL10A PE=1 SV=2 6.07 3285.7 - 92312.6 - - - 1.6262 - 1.424 0.152 - 84.6 1 2 0 0.0024 13 0 0 0 1.64E+06 1.81E+06 - - - 1.1923 1 221125_WJC_METTL3_EV_vs_WT_F07.20424.20424.4 9.02E-07 21/126 K.QAVDFLSNEGHIYSTVDDDHFK[136.11].S "sp|P15927|RFA2_HUMAN,tr|Q5TEJ0|Q5TEJ0_HUMAN" 2 2544.1648 1.31 105982 20424 4 2544.167447 637.0485 Replication protein A 32 kDa subunit OS=Homo sapiens OX=9606 GN=RPA2 PE=1 SV=1 4.34 3286.4 - 1.06E+06 - - - 1.0219 - 3.448 0.561 - 295 1 2 0 0.0026 22 0 0 0 8.34E+07 6.34E+07 - - - 4.5132 1 221125_WJC_METTL3_EV_vs_WT_F07.20429.20429.3 2.24E-11 14/68 K.DFDFESANAQFNK[136.11]EEIDR[166.11].E "sp|Q8ND56|LS14A_HUMAN,tr|A0A140TA76|A0A140TA76_HUMAN,tr|K7EMZ9|K7EMZ9_HUMAN" 3 2191.9777 1.06 105985 20429 3 2191.978238 731.6665 Protein LSM14 homolog A OS=Homo sapiens OX=9606 GN=LSM14A PE=1 SV=3 4.02 3287.1 - 381967 - - - 0.24 - 3.085 0.696 - 134 1 2 1 0.0005 18 0 0 0 4.90E+07 4.63E+07 - - - 9.1048 0.9999 221125_WJC_METTL3_EV_vs_WT_F07.20431.20431.4 2.11E-07 17/108 R.TSQNSELNNMQDLVEDYKK.K sp|P35908|K22E_HUMAN 1 2255.0376 0.71 105987 20431 4 2255.042284 564.7667 "Keratin, type II cytoskeletal 2 epidermal OS=Homo sapiens OX=9606 GN=KRT2 PE=1 SV=2" 4.32 3287.3 - 979842 - - - 2.0811 - 2.875 0.466 - 168.9 1 2 0 0.0047 19 0 0 0 4.30E+07 6.05E+07 - - - 3.638 1 221125_WJC_METTL3_EV_vs_WT_F07.20432.20432.3 3.89E-09 19/80 K.KGQLNADEISLRPAQSFLMNK.N "sp|P78344|IF4G2_HUMAN,tr|D3DQV9|D3DQV9_HUMAN" 2 2359.2318 1.4 105988 20432 3 2359.231739 787.4179 Eukaryotic translation initiation factor 4 gamma 2 OS=Homo sapiens OX=9606 GN=EIF4G2 PE=1 SV=1 8.59 3287.5 - 521150 - - - -0.0322 - 3.546 0.575 - 329.4 1 2 0 -0.0001 21 0 0 0 3.69E+07 2.64E+07 - - - 7.9854 1 221125_WJC_METTL3_EV_vs_WT_F07.20438.20438.3 3.61E-08 19/68 K.DFDFESANAQFNKEEIDR.E "sp|Q8ND56|LS14A_HUMAN,tr|A0A140TA76|A0A140TA76_HUMAN,tr|K7EMZ9|K7EMZ9_HUMAN" 3 2173.9552 1.06 105991 20438 3 2173.959928 725.659 Protein LSM14 homolog A OS=Homo sapiens OX=9606 GN=LSM14A PE=1 SV=3 4.02 3288.2 - 501608 - - - 2.1555 - 3.788 0.663 - 303.4 1 2 1 0.0047 18 0 0 0 4.90E+07 4.63E+07 - - - 9.2469 0.964 221125_WJC_METTL3_EV_vs_WT_F07.20439.20439.3 1.66E-05 14/72 K.SKELTTEIDNNIEQISSYK.S "sp|P13645|K1C10_HUMAN,tr|A0A1B0GVI3|A0A1B0GVI3_HUMAN" 2 2211.0907 999 105992 20439 3 2212.084895 738.0375 "Keratin, type I cytoskeletal 10 OS=Homo sapiens OX=9606 GN=KRT10 PE=1 SV=6" 4.41 3288.4 - 331009 - - - 449.6523 - 2.861 0.498 - 194.4 1 2 1 0.9942 19 0 0 0 2.07E+06 0.00E+00 - - - 6.3993 1 221125_WJC_METTL3_EV_vs_WT_F07.20442.20442.3 9.21E-12 16/108 R.MQNNSSPSISPNTSFTSDGSPSPLGGIK.R sp|Q9H0D6|XRN2_HUMAN 1 2806.308 1.27 105993 20442 3 2806.307569 936.4433 5'-3' exoribonuclease 2 OS=Homo sapiens OX=9606 GN=XRN2 PE=1 SV=1 5.59 3288.8 - 719687 - - - -0.1368 - 3.278 0.698 - 165.4 1 2 0 -0.0004 28 0 0 0 7.18E+07 5.66E+07 - - - 9.0533 0.9999 221125_WJC_METTL3_EV_vs_WT_F07.20456.20456.4 1.06E-05 16/126 K.QAVDFLSNEGHIYSTVDDDHFK.S "sp|P15927|RFA2_HUMAN,tr|Q5TEJ0|Q5TEJ0_HUMAN" 2 2536.1506 1.32 106003 20456 4 2536.154191 635.0449 Replication protein A 32 kDa subunit OS=Homo sapiens OX=9606 GN=RPA2 PE=1 SV=1 4.34 3290.6 - 3.97E+06 - - - 1.3974 - 2.888 0.468 - 159.3 1 2 0 0.0035 22 0 0 0 8.36E+07 6.35E+07 - - - 3.6455 1 221125_WJC_METTL3_EV_vs_WT_F07.20457.20457.3 2.70E-11 21/60 K.HSQAVEELAEQLEQTK[136.11].R sp|P35579|MYH9_HUMAN 1 1846.9152 1.09 106004 20457 3 1846.915386 616.6457 Myosin-9 OS=Homo sapiens OX=9606 GN=MYH9 PE=1 SV=4 4.48 3290.7 - 1.19E+06 - - - 0.0893 - 4.156 0.626 - 735.6 1 2 0 0.0002 16 0 0 0 5.61E+07 5.15E+07 - - - 9.1744 1 221125_WJC_METTL3_EV_vs_WT_F07.20458.20458.3 2.50E-15 21/108 R.MQNNSSPSISPNTSFTSDGSPSPLGGIK[136.11].R sp|Q9H0D6|XRN2_HUMAN 1 2814.3222 1.27 106005 20458 3 2814.310622 939.1147 5'-3' exoribonuclease 2 OS=Homo sapiens OX=9606 GN=XRN2 PE=1 SV=1 5.59 3290.8 - 918078 - - - -4.0973 - 3.841 0.752 - 371.7 1 2 0 -0.0115 28 0 0 0 7.19E+07 5.66E+07 - - - 10.0169 0.9998 221125_WJC_METTL3_EV_vs_WT_F07.20466.20466.2 0.00938 14-Oct R.VDEIIWVK[136.11].T sp|Q86U44|MTA70_HUMAN 1 1008.5735 0.02 106011 20466 2 1008.57318 505.294 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 4.37 3291.8 - 582156 - - - -0.35 - 2.228 0.353 - 347.7 1 2 0 -0.0004 8 0 0 0 1.96E+06 1.13E+08 - - - 4.0642 1 221125_WJC_METTL3_EV_vs_WT_F07.20467.20467.4 9.40E-09 20/126 K.KIEEAMDGSETPQLFTVLPEKR.T "sp|Q13435|SF3B2_HUMAN,tr|E9PPJ0|E9PPJ0_HUMAN" 2 2517.2785 0.93 106012 20467 4 2517.279651 630.3269 Splicing factor 3B subunit 2 OS=Homo sapiens OX=9606 GN=SF3B2 PE=1 SV=2 4.59 3292 - 419771 - - - 0.4612 - 2.993 0.582 - 216.6 1 2 0 0.0012 22 0 0 0 1.44E+07 1.54E+07 - - - 4.6501 1 221125_WJC_METTL3_EV_vs_WT_F07.20473.20473.3 1.18E-11 22/60 K.HSQAVEELAEQLEQTK.R sp|P35579|MYH9_HUMAN 1 1838.901 1.09 106015 20473 3 1838.901992 613.9743 Myosin-9 OS=Homo sapiens OX=9606 GN=MYH9 PE=1 SV=4 4.48 3292.7 - 1.95E+06 - - - 0.528 - 3.977 0.66 - 860.7 1 2 0 0.001 16 0 0 0 5.63E+07 5.16E+07 - - - 9.4403 0.9999 221125_WJC_METTL3_EV_vs_WT_F07.20474.20474.4 8.47E-09 22/96 K.GKFGHEFLEFEFRPDGK.L "sp|Q96A72|MGN2_HUMAN,sp|P61326|MGN_HUMAN,tr|F5H6N1|F5H6N1_HUMAN" 3 2038.9901 1.5 106016 20474 4 2038.991039 510.7548 Protein mago nashi homolog 2 OS=Homo sapiens OX=9606 GN=MAGOHB PE=1 SV=1 5.53 3292.8 - 705681 - - - 0.4551 - 3.937 0.554 - 433.7 1 2 1 0.0009 17 0 0 0 2.71E+07 1.80E+07 - - - 4.5236 1 221125_WJC_METTL3_EV_vs_WT_F07.20480.20480.3 4.98E-11 28/148 R.LASPSGSTSSGLEVVAPEGTSAPGGGPGTLDDSATIC[160.03]R.V "sp|Q13263|TIF1B_HUMAN,tr|M0R0K9|M0R0K9_HUMAN" 2 3557.6792 0.9 106020 20480 3 3557.682607 1186.9003 Transcription intermediary factor 1-beta OS=Homo sapiens OX=9606 GN=TRIM28 PE=1 SV=5 3.92 3293.6 - 771525 - - - 0.9714 - 4.911 0.723 - 423.7 1 2 0 0.0035 38 0 0 0 2.10E+07 2.35E+07 - - - 10.2612 1 221125_WJC_METTL3_EV_vs_WT_F07.20481.20481.4 1.85E-08 21/138 K.KVTSVVFHPSQDLVFSASPDATIR.L sp|Q9UMS4|PRP19_HUMAN 1 2600.3599 1.28 106021 20481 4 2600.364997 651.0972 Pre-mRNA-processing factor 19 OS=Homo sapiens OX=9606 GN=PRPF19 PE=1 SV=1 6.75 3293.7 - 1.19E+06 - - - 1.9786 - 3.652 0.562 - 297.8 1 2 0 0.0051 24 0 0 0 2.27E+07 1.78E+07 - - - 4.532 0.9998 221125_WJC_METTL3_EV_vs_WT_F07.20484.20484.4 0.000101 20/96 K.GK[136.11]FGHEFLEFEFR[166.11]PDGK[136.11].L "sp|Q96A72|MGN2_HUMAN,sp|P61326|MGN_HUMAN,tr|F5H6N1|F5H6N1_HUMAN" 3 2065.0268 1.53 106024 20484 4 2065.030754 517.264 Protein mago nashi homolog 2 OS=Homo sapiens OX=9606 GN=MAGOHB PE=1 SV=1 5.53 3294.1 - 553502 - - - 1.9239 - 3.782 0.48 - 312.6 1 2 1 0.004 17 0 0 0 2.78E+07 1.82E+07 - - - 3.8647 1 221125_WJC_METTL3_EV_vs_WT_F07.20490.20490.4 0.000609 24/138 K.K[136.11]VTSVVFHPSQDLVFSASPDATIR[166.11].L sp|Q9UMS4|PRP19_HUMAN 1 2618.3823 1.28 106028 20490 4 2618.385861 655.6029 Pre-mRNA-processing factor 19 OS=Homo sapiens OX=9606 GN=PRPF19 PE=1 SV=1 6.75 3294.9 - 1.33E+06 - - - 1.3516 - 3.996 0.498 - 421 1 2 0 0.0035 24 0 0 0 2.27E+07 1.78E+07 - - - 4.0042 1 221125_WJC_METTL3_EV_vs_WT_F07.20491.20491.3 7.04E-10 18/92 K.KVTSVVFHPSQDLVFSASPDATIR.L sp|Q9UMS4|PRP19_HUMAN 1 2600.3599 2.49 106029 20491 3 2600.356462 867.7939 Pre-mRNA-processing factor 19 OS=Homo sapiens OX=9606 GN=PRPF19 PE=1 SV=1 6.75 3295 - 705659 - - - -1.3037 - 3.921 0.646 - 291.5 1 2 0 -0.0034 24 0 0 0 7.44E+06 2.99E+06 - - - 8.9148 1 221125_WJC_METTL3_EV_vs_WT_F07.20492.20492.3 1.59E-10 14/84 K.KIEEAMDGSETPQLFTVLPEKR.T "sp|Q13435|SF3B2_HUMAN,tr|E9PPJ0|E9PPJ0_HUMAN" 2 2517.2785 0.84 106030 20492 3 2517.284899 840.1001 Splicing factor 3B subunit 2 OS=Homo sapiens OX=9606 GN=SF3B2 PE=1 SV=2 4.59 3295.1 - 282141 - - - 2.546 - 2.928 0.632 - 213.8 1 2 0 0.0064 22 0 0 0 1.39E+06 1.65E+06 - - - 8.1314 0.9998 221125_WJC_METTL3_EV_vs_WT_F07.20497.20497.4 0.000194 12/108 R.GLLQDDAHPTLVTYADHSK[136.11].L "sp|Q86U44|MTA70_HUMAN,tr|F5H6D8|F5H6D8_HUMAN,tr|H0YFV6|H0YFV6_HUMAN,tr|B4DTN4|B4DTN4_HUMAN" 4 2088.0367 0.01 106033 20497 4 2088.042379 523.0165 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 5.13 3295.8 - 337264 - - - 2.704 - 2.531 0.437 - 127.3 1 2 0 0.0056 19 0 0 0 1.71E+05 1.55E+07 - - - 3.3422 1 221125_WJC_METTL3_EV_vs_WT_F07.20500.20500.3 4.13E-16 34/148 R.LASPSGSTSSGLEVVAPEGTSAPGGGPGTLDDSATIC[160.03]R[166.11].V "sp|Q13263|TIF1B_HUMAN,tr|M0R0K9|M0R0K9_HUMAN" 2 3567.6874 0.9 106034 20500 3 3567.687278 1190.2364 Transcription intermediary factor 1-beta OS=Homo sapiens OX=9606 GN=TRIM28 PE=1 SV=5 3.92 3296.2 - 1.29E+06 - - - -0.0401 - 5.411 0.711 - 702.9 1 2 0 -0.0001 38 0 0 0 2.10E+07 2.35E+07 - - - 10.3514 1 221125_WJC_METTL3_EV_vs_WT_F07.20501.20501.4 1.07E-14 28/126 R.FHVNLLC[160.03]GEEQGSDAALHFNPR.L sp|P47929|LEG7_HUMAN 1 2510.1761 11.36 106035 20501 4 2510.181286 628.5513 Galectin-7 OS=Homo sapiens OX=9606 GN=LGALS7 PE=1 SV=2 5.27 3296.3 - 1.13E+06 - - - 2.0696 - 5.199 0.691 - 760.1 1 2 0 0.0052 22 0 0 0 1.49E+07 1.31E+06 - - - 5.7784 1 221125_WJC_METTL3_EV_vs_WT_F07.20502.20502.4 9.11E-08 28/222 R.LASPSGSTSSGLEVVAPEGTSAPGGGPGTLDDSATIC[160.03]R[166.11].V "sp|Q13263|TIF1B_HUMAN,tr|M0R0K9|M0R0K9_HUMAN" 2 3567.6874 1.11 106036 20502 4 3567.689897 892.9291 Transcription intermediary factor 1-beta OS=Homo sapiens OX=9606 GN=TRIM28 PE=1 SV=5 3.92 3296.5 - 664770 - - - 0.694 - 5.698 0.633 - 410 1 2 0 0.0025 38 0 0 0 1.19E+07 1.07E+07 - - - 5.2424 1 221125_WJC_METTL3_EV_vs_WT_F07.20504.20504.3 6.13E-10 15/100 R.VGAGDTSDWPTVLSESSTTVAGK[136.11]PEK[136.11].G sp|Q9BUA3|SPNDC_HUMAN 1 2634.2996 3.24 106038 20504 3 2634.304833 879.1071 Spindlin interactor and repressor of chromatin-binding protein OS=Homo sapiens OX=9606 GN=SPINDOC PE=1 SV=3 4.32 3296.7 - 380185 - - - 2.0032 - 3.067 0.633 - 191.4 1 2 0 0.0053 26 0 0 0 1.02E+08 3.16E+07 - - - 8.1742 0.9999 221125_WJC_METTL3_EV_vs_WT_F07.20510.20510.3 2.02E-06 19/76 R.EK[136.11]QSDDEVYAPGLDIESSLK[136.11].Q sp|Q15459|SF3A1_HUMAN 1 2238.0874 0.88 106042 20510 3 2238.087361 747.0364 Splicing factor 3A subunit 1 OS=Homo sapiens OX=9606 GN=SF3A1 PE=1 SV=1 4.02 3297.5 - 979694 - - - -0.0344 - 3.456 0.552 - 374.4 1 2 1 -0.0001 20 0 0 0 1.03E+07 1.17E+07 - - - 7.7028 0.9999 221125_WJC_METTL3_EV_vs_WT_F07.20519.20519.3 2.90E-10 19/64 K.K[136.11]IGDEYFTFITDC[160.03]K[136.11]DPK[136.11].A "sp|P49368|TCPG_HUMAN,tr|B4DUR8|B4DUR8_HUMAN" 2 2100.03 0.27 106049 20519 3 2100.034527 701.0173 T-complex protein 1 subunit gamma OS=Homo sapiens OX=9606 GN=CCT3 PE=1 SV=4 4.68 3298.7 - 836388 - - - 2.1585 - 3.466 0.549 - 313.8 1 2 1 0.0045 17 0 0 0 1.33E+07 4.97E+07 - - - 7.7997 1 221125_WJC_METTL3_EV_vs_WT_F07.20521.20521.4 2.90E-14 32/222 R.LASPSGSTSSGLEVVAPEGTSAPGGGPGTLDDSATIC[160.03]R.V "sp|Q13263|TIF1B_HUMAN,tr|M0R0K9|M0R0K9_HUMAN" 2 3557.6792 1.11 106051 20521 4 3557.688 890.4271 Transcription intermediary factor 1-beta OS=Homo sapiens OX=9606 GN=TRIM28 PE=1 SV=5 3.92 3299 - 650973 - - - 2.4873 - 5.296 0.604 - 536.8 1 2 0 0.0089 38 0 0 0 1.19E+07 1.07E+07 - - - 4.9669 0.9932 221125_WJC_METTL3_EV_vs_WT_F07.20522.20522.4 2.89E-11 23/150 F.LGHLHQVQLAGTSLQAAAQSLNVQSK.S "sp|P14859|PO2F1_HUMAN,tr|A0A0A0MT46|A0A0A0MT46_HUMAN" 2 2698.4515 1.86 106052 20522 4 2698.460125 675.6201 "POU domain, class 2, transcription factor 1 OS=Homo sapiens OX=9606 GN=POU2F1 PE=1 SV=2" 8.76 3299.1 - 551299 - - - 3.2107 - 4.725 0.575 - 458.5 1 1 0 0.0087 26 0 0 0 1.47E+07 7.89E+06 - - - 4.7182 0.9996 221125_WJC_METTL3_EV_vs_WT_F07.20530.20530.4 0.00144 Nov-96 K.K[136.11]IGDEYFTFITDC[160.03]K[136.11]DPK[136.11].A "sp|P49368|TCPG_HUMAN,tr|B4DUR8|B4DUR8_HUMAN" 2 2100.03 0.24 106058 20530 4 2100.03265 526.0148 T-complex protein 1 subunit gamma OS=Homo sapiens OX=9606 GN=CCT3 PE=1 SV=4 4.68 3300 - 1.30E+06 - - - 1.2647 - 1.883 0.426 - 77 1 2 1 0.0027 17 0 0 0 9.23E+06 3.85E+07 - - - 3.1529 0.9999 221125_WJC_METTL3_EV_vs_WT_F07.20531.20531.4 6.05E-05 22/90 K.ELHDLFNLPHDR[166.11]PYFK[136.11].R "sp|Q9NUQ7|UFSP2_HUMAN,tr|D6RGX2|D6RGX2_HUMAN,tr|H0YA18|H0YA18_HUMAN" 3 2058.0442 1.35 106059 20531 4 2058.042741 515.5183 Ufm1-specific protease 2 OS=Homo sapiens OX=9606 GN=UFSP2 PE=1 SV=3 6.01 3300.1 - 892891 - - - -0.7167 - 3.58 0.443 - 444.2 1 2 0 -0.0015 16 0 0 0 2.10E+07 1.55E+07 - - - 3.5307 0.9991 221125_WJC_METTL3_EV_vs_WT_F07.20534.20534.4 0.00581 9/126 K.K[136.11]IEEAMDGSETPQLFTVLPEK[136.11]R[166.11].T "sp|Q13435|SF3B2_HUMAN,tr|E9PPJ0|E9PPJ0_HUMAN" 2 2543.3152 0.93 106062 20534 4 2543.318501 636.8361 Splicing factor 3B subunit 2 OS=Homo sapiens OX=9606 GN=SF3B2 PE=1 SV=2 4.59 3300.5 - 276538 - - - 1.3136 - 2.139 0.302 - 51.8 1 2 0 0.0033 22 0 0 0 1.45E+07 1.56E+07 - - - 2.1025 0.9999 221125_WJC_METTL3_EV_vs_WT_F07.20540.20540.4 3.66E-09 28/144 K.TVLHTGSAPSSSTPFNKEELSAILK.F sp|O14646|CHD1_HUMAN 1 2613.365 1.03 106066 20540 4 2613.372193 654.3485 Chromodomain-helicase-DNA-binding protein 1 OS=Homo sapiens OX=9606 GN=CHD1 PE=1 SV=2 6.42 3301.2 - 809566 - - - 2.7535 - 4.574 0.61 - 539.5 1 2 1 0.0072 25 0 0 0 1.07E+07 1.05E+07 - - - 5.0171 1 221125_WJC_METTL3_EV_vs_WT_F07.20542.20542.3 9.09E-16 20/88 R.EHNFQPGDNVEVC[160.03]EGELINLQGK.L sp|O00267|SPT5H_HUMAN 1 2625.2129 1.55 106068 20542 3 2625.215993 876.0783 Transcription elongation factor SPT5 OS=Homo sapiens OX=9606 GN=SUPT5H PE=1 SV=1 4.25 3301.5 - 489994 - - - 1.1668 - 4.353 0.737 - 479 1 2 0 0.0031 23 0 0 0 1.69E+07 1.09E+07 - - - 10.2065 1 221125_WJC_METTL3_EV_vs_WT_F07.20544.20544.4 1.21E-10 19/162 K.HSVEVTNC[160.03]FSVPHNESEDEVAVDMEFAK.N "sp|O00303|EIF3F_HUMAN,tr|H0YDT6|H0YDT6_HUMAN,tr|A0A7I2YQA0|A0A7I2YQA0_HUMAN" 3 3205.3968 1.12 106070 20544 4 3205.416274 802.3565 Eukaryotic translation initiation factor 3 subunit F OS=Homo sapiens OX=9606 GN=EIF3F PE=1 SV=1 4.24 3301.8 - 446689 - - - 6.0617 - 3.566 0.666 - 176 1 2 0 0.0194 28 0 0 0 3.02E+06 2.69E+06 - - - 5.4122 0.9991 221125_WJC_METTL3_EV_vs_WT_F07.20545.20545.4 0.00123 Dec-96 K.KIGDEYFTFITDC[160.03]KDPK.A "sp|P49368|TCPG_HUMAN,tr|B4DUR8|B4DUR8_HUMAN" 2 2075.9874 0.24 106071 20545 4 2075.993493 520.0041 T-complex protein 1 subunit gamma OS=Homo sapiens OX=9606 GN=CCT3 PE=1 SV=4 4.68 3301.9 - 418416 - - - 2.9379 - 2.004 0.448 - 75.9 1 2 1 0.0061 17 0 0 0 9.23E+06 3.85E+07 - - - 3.3651 1 221125_WJC_METTL3_EV_vs_WT_F07.20554.20554.3 6.60E-09 13/132 R.EATDTPIVIQPASATETTQLTADSHPSYHTDGFN.- sp|Q9H3Z4|DNJC5_HUMAN 1 3614.6649 - 106078 20554 3 3614.667955 1205.8956 DnaJ homolog subfamily C member 5 OS=Homo sapiens OX=9606 GN=DNAJC5 PE=1 SV=1 4.1 3303.1 - 266739 - - - 0.8507 - 2.663 0.655 - 84.8 1 2 0 0.0031 34 0 0 0 - - - - - 8.0951 1 221125_WJC_METTL3_EV_vs_WT_F07.20558.20558.4 3.60E-06 24/186 K.VGGTNLGAPGAFGQSPFSQPPAPPHQNTFPPR.S sp|Q96I24|FUBP3_HUMAN 1 3227.5901 2.49 106080 20558 4 3227.594514 807.9048 Far upstream element-binding protein 3 OS=Homo sapiens OX=9606 GN=FUBP3 PE=1 SV=2 9.73 3303.6 - 2.67E+06 - - - 1.3738 - 4.296 0.521 - 177.9 1 2 0 0.0044 32 0 0 0 3.84E+07 1.54E+07 - - - 4.1997 0.9424 221125_WJC_METTL3_EV_vs_WT_F07.20562.20562.4 8.60E-05 10/108 T.ISANGDKEIGNIISDAMKK.V "sp|P10809|CH60_HUMAN,tr|A0A7I2V599|A0A7I2V599_HUMAN,tr|E7EXB4|E7EXB4_HUMAN,tr|A0A7I2YQ71|A0A7I2YQ71_HUMAN,tr|E7ESH4|E7ESH4_HUMAN,tr|A0A7I2V5M1|A0A7I2V5M1_HUMAN,tr|A0A7I2V5K3|A0A7I2V5K3_HUMAN,tr|A0A7I2V369|A0A7I2V369_HUMAN" 8 2003.0357 0.92 106084 20562 4 2003.032365 501.7662 "60 kDa heat shock protein, mitochondrial OS=Homo sapiens OX=9606 GN=HSPD1 PE=1 SV=2" 6.12 3304.1 - 452309 - - - -1.6854 - 2.145 0.421 - 64.1 1 1 1 -0.0034 19 0 0 0 6.81E+06 7.37E+06 - - - 3.1476 0.9998 221125_WJC_METTL3_EV_vs_WT_F07.20564.20564.3 6.06E-05 15/60 K.SSKGELTTLIHQLQEK.D sp|Q86UP2|KTN1_HUMAN 1 1810.9789 2.06 106086 20564 3 1810.980575 604.6669 Kinectin OS=Homo sapiens OX=9606 GN=KTN1 PE=1 SV=1 6.48 3304.4 - 294007 - - - 0.9371 - 2.652 0.46 - 164.7 1 2 1 0.0017 16 0 0 0 7.32E+06 3.55E+06 - - - 6.1706 1 221125_WJC_METTL3_EV_vs_WT_F07.20569.20569.4 1.03E-11 18/162 K.VQSVETVEGC[160.03]THEVALPAEEDYLPLK[136.11]PR[166.11].V sp|P42285|MTREX_HUMAN 1 3183.5877 1.25 106089 20569 4 3183.588164 796.9042 Exosome RNA helicase MTR4 OS=Homo sapiens OX=9606 GN=MTREX PE=1 SV=3 4.41 3305 - 835571 - - - 0.1457 - 3.211 0.516 - 146 1 2 0 0.0005 28 0 0 0 1.04E+07 8.30E+06 - - - 4.0793 1 221125_WJC_METTL3_EV_vs_WT_F07.20570.20570.4 3.10E-09 15/162 K.VQSVETVEGC[160.03]THEVALPAEEDYLPLKPR.V sp|P42285|MTREX_HUMAN 1 3165.5652 1.5 106090 20570 4 3165.564378 792.3986 Exosome RNA helicase MTR4 OS=Homo sapiens OX=9606 GN=MTREX PE=1 SV=3 4.41 3305.2 - 665511 - - - -0.2691 - 2.942 0.527 - 51.5 1 2 0 -0.0009 28 0 0 0 1.27E+07 8.47E+06 - - - 4.1478 1 221125_WJC_METTL3_EV_vs_WT_F07.20571.20571.3 2.88E-08 17/112 K.TLSSPSNRPSGETSVPPPPAAPPFLPVGR.M tr|H3BUF6|H3BUF6_HUMAN 1 2911.5192 1.74 106091 20571 3 2911.517819 971.5137 Ataxin-2-like protein OS=Homo sapiens OX=9606 GN=ATXN2L PE=1 SV=1 9.26 3305.3 - 530831 - - - -0.4764 - 2.974 0.595 - 235.2 1 2 0 -0.0014 29 0 0 0 9.93E+06 5.70E+06 - - - 7.6808 1 221125_WJC_METTL3_EV_vs_WT_F07.20579.20579.3 4.12E-15 23/112 R.SAAGFEPVPEC[160.03]SDGAIHSWAVEGPQPEPR.D sp|Q02413|DSG1_HUMAN 1 3076.3985 999 106096 20579 3 3076.396737 1026.4734 Desmoglein-1 OS=Homo sapiens OX=9606 GN=DSG1 PE=1 SV=2 4.25 3306.3 - 831613 - - - -0.5727 - 3.839 0.709 - 381.2 1 2 0 -0.0018 29 0 0 0 1.61E+07 0.00E+00 - - - 9.539 1 221125_WJC_METTL3_EV_vs_WT_F07.20580.20580.4 3.06E-11 30/132 R.IRNELMQSLNQDSNSNFKDTLLK.E "sp|Q15643|TRIPB_HUMAN,tr|H0YJ97|H0YJ97_HUMAN" 2 2707.3599 1.26 106097 20580 4 2707.359295 677.8473 Thyroid receptor-interacting protein 11 OS=Homo sapiens OX=9606 GN=TRIP11 PE=1 SV=3 6.12 3306.5 - 1.54E+06 - - - -0.2342 - 4.477 0.626 - 649.6 1 2 2 -0.0006 23 0 0 0 8.04E+07 6.40E+07 - - - 5.1602 1 221125_WJC_METTL3_EV_vs_WT_F07.20581.20581.4 1.38E-07 24/186 K.VGGTNLGAPGAFGQSPFSQPPAPPHQNTFPPR[166.11].S sp|Q96I24|FUBP3_HUMAN 1 3237.5984 2.48 106098 20581 4 3237.603027 810.4069 Far upstream element-binding protein 3 OS=Homo sapiens OX=9606 GN=FUBP3 PE=1 SV=2 9.73 3306.6 - 858591 - - - 1.4446 - 3.708 0.532 - 137.1 1 2 0 0.0047 32 0 0 0 4.01E+07 1.62E+07 - - - 4.2509 1 221125_WJC_METTL3_EV_vs_WT_F07.20582.20582.3 1.43E-16 20/88 R.EHNFQPGDNVEVC[160.03]EGELINLQGK[136.11].L sp|O00267|SPT5H_HUMAN 1 2633.2271 1.57 106099 20582 3 2633.218905 878.7497 Transcription elongation factor SPT5 OS=Homo sapiens OX=9606 GN=SUPT5H PE=1 SV=1 4.25 3306.7 - 714119 - - - -3.1235 - 3.699 0.724 - 472.5 1 2 0 -0.0082 23 0 0 0 1.71E+07 1.09E+07 - - - 9.6782 1 221125_WJC_METTL3_EV_vs_WT_F07.20587.20587.3 2.72E-13 25/104 K.LESPSFTGTGDTEIAHATEDLENNGSK.K sp|Q08J23|NSUN2_HUMAN 1 2819.2733 1.64 106102 20587 3 2819.264292 940.7651 RNA cytosine C(5)-methyltransferase NSUN2 OS=Homo sapiens OX=9606 GN=NSUN2 PE=1 SV=2 4.08 3307.4 - 565491 - - - -3.2097 - 4.846 0.707 - 695.8 1 2 0 -0.009 27 0 0 0 6.47E+06 3.95E+06 - - - 10.0506 1 221125_WJC_METTL3_EV_vs_WT_F07.20588.20588.3 6.79E-08 13/112 K.TLSSPSNR[166.11]PSGETSVPPPPAAPPFLPVGR[166.11].M tr|H3BUF6|H3BUF6_HUMAN 1 2931.5357 1.74 106103 20588 3 2931.533956 978.1859 Ataxin-2-like protein OS=Homo sapiens OX=9606 GN=ATXN2L PE=1 SV=1 9.26 3307.5 - 311459 - - - -0.6106 - 2.701 0.651 - 122.8 1 2 0 -0.0018 29 0 0 0 9.93E+06 5.70E+06 - - - 8.0835 0.9999 221125_WJC_METTL3_EV_vs_WT_F07.20594.20594.3 0.000219 13/72 K.HSSDASSLLPQNILSQTSR.H "sp|Q9BTA9|WAC_HUMAN,tr|A0A7P0T961|A0A7P0T961_HUMAN,tr|J3QTA0|J3QTA0_HUMAN" 3 2040.0236 0.32 106107 20594 3 2040.02851 681.0151 WW domain-containing adapter protein with coiled-coil OS=Homo sapiens OX=9606 GN=WAC PE=1 SV=3 6.74 3308.3 - 392814 - - - 2.4088 - 2.781 0.429 - 212 1 2 0 0.0049 19 0 0 0 9.14E+06 2.82E+07 - - - 5.8344 0.8008 221125_WJC_METTL3_EV_vs_WT_F07.20596.20596.4 0.0045 9/108 T.ISANGDK[136.11]EIGNIISDAMK[136.11]K[136.11].V "sp|P10809|CH60_HUMAN,tr|A0A7I2V599|A0A7I2V599_HUMAN,tr|E7EXB4|E7EXB4_HUMAN,tr|A0A7I2YQ71|A0A7I2YQ71_HUMAN,tr|E7ESH4|E7ESH4_HUMAN,tr|A0A7I2V5M1|A0A7I2V5M1_HUMAN,tr|A0A7I2V5K3|A0A7I2V5K3_HUMAN,tr|A0A7I2V369|A0A7I2V369_HUMAN" 8 2027.0783 0.86 106109 20596 4 2027.081079 507.7769 "60 kDa heat shock protein, mitochondrial OS=Homo sapiens OX=9606 GN=HSPD1 PE=1 SV=2" 6.12 3308.6 - 297659 - - - 1.3507 - 1.651 0.342 - 46.6 1 1 1 0.0027 19 0 0 0 7.01E+06 8.11E+06 - - - 2.3716 1 221125_WJC_METTL3_EV_vs_WT_F07.20599.20599.4 8.13E-12 23/132 R.IR[166.11]NELMQSLNQDSNSNFK[136.11]DTLLK[136.11].E "sp|Q15643|TRIPB_HUMAN,tr|H0YJ97|H0YJ97_HUMAN" 2 2733.3966 1.26 106110 20599 4 2733.399628 684.3564 Thyroid receptor-interacting protein 11 OS=Homo sapiens OX=9606 GN=TRIP11 PE=1 SV=3 6.12 3309 - 4.14E+06 - - - 1.1081 - 4.415 0.642 - 336.4 1 2 2 0.003 23 0 0 0 7.95E+07 6.30E+07 - - - 5.2943 1 221125_WJC_METTL3_EV_vs_WT_F07.20600.20600.3 2.46E-18 32/88 R.IRNELMQSLNQDSNSNFKDTLLK.E "sp|Q15643|TRIPB_HUMAN,tr|H0YJ97|H0YJ97_HUMAN" 2 2707.3599 1.33 106111 20600 3 2707.363975 903.4606 Thyroid receptor-interacting protein 11 OS=Homo sapiens OX=9606 GN=TRIP11 PE=1 SV=3 6.12 3309.1 - 1.33E+06 - - - 1.4944 - 5.827 0.657 - 1356.6 1 2 2 0.004 23 0 0 0 1.97E+07 1.49E+07 - - - 9.9985 1 221125_WJC_METTL3_EV_vs_WT_F07.20610.20610.3 7.02E-07 25/124 K.VGGTNLGAPGAFGQSPFSQPPAPPHQNTFPPR.S sp|Q96I24|FUBP3_HUMAN 1 3227.5901 2.58 106119 20610 3 3227.595493 1076.8706 Far upstream element-binding protein 3 OS=Homo sapiens OX=9606 GN=FUBP3 PE=1 SV=2 9.73 3310.3 - 835646 - - - 1.6771 - 3.937 0.612 - 345.7 1 2 0 0.0054 32 0 0 0 3.19E+07 1.24E+07 - - - 8.5145 1 221125_WJC_METTL3_EV_vs_WT_F07.20616.20616.3 1.29E-09 18/84 K.QQTTLTEWYSAQENSFKPESQR.Q "sp|Q9H6S0|YTDC2_HUMAN,tr|D6RA70|D6RA70_HUMAN" 2 2657.2358 0.69 106125 20616 3 2657.236616 886.7525 3'-5' RNA helicase YTHDC2 OS=Homo sapiens OX=9606 GN=YTHDC2 PE=1 SV=2 4.79 3311.1 - 344701 - - - 0.3169 - 3.617 0.618 - 261.7 1 2 0 0.0008 22 0 0 0 5.18E+06 7.51E+06 - - - 8.4779 1 221125_WJC_METTL3_EV_vs_WT_F07.20622.20622.4 1.48E-05 24/174 R.SIFGEDALANVSIEK[136.11]PIHQGPDAAVTGHIR[166.11].L sp|P53618|COPB_HUMAN 1 3159.6432 1.07 106129 20622 4 3159.643152 790.9181 Coatomer subunit beta OS=Homo sapiens OX=9606 GN=COPB1 PE=1 SV=3 5.3 3311.9 - 662869 - - - -0.0092 - 4.234 0.497 - 311.9 1 2 0 0 30 0 0 0 1.12E+07 1.04E+07 - - - 3.9935 1 221125_WJC_METTL3_EV_vs_WT_F07.20625.20625.4 2.03E-17 30/198 R.HTEVLPAEEENDSLGADGTHGAGAMESAAGVLIK.L sp|Q6P2E9|EDC4_HUMAN 1 3375.5889 1.28 106132 20625 4 3375.599109 844.9045 Enhancer of mRNA-decapping protein 4 OS=Homo sapiens OX=9606 GN=EDC4 PE=1 SV=1 4.24 3312.3 - 358621 - - - 3.0306 - 5.338 0.717 - 378.1 1 2 0 0.0102 34 0 0 0 4.11E+06 3.21E+06 - - - 5.9634 1 221125_WJC_METTL3_EV_vs_WT_F07.20633.20633.3 3.38E-10 16/92 R.ATC[160.03]NNYTPQFQLRPSYSSC[160.03]FPQYR.S sp|Q5T749|KPRP_HUMAN 1 2984.3334 778.2 106138 20633 3 2984.334685 995.7851 Keratinocyte proline-rich protein OS=Homo sapiens OX=9606 GN=KPRP PE=1 SV=1 8.86 3313.3 - 737192 - - - 0.4316 - 3.002 0.695 - 140 1 2 0 0.0013 24 0 0 0 8.29E+07 1.06E+05 - - - 8.8414 1 221125_WJC_METTL3_EV_vs_WT_F07.20635.20635.3 0.203 15/124 K.VGGTNLGAPGAFGQSPFSQPPAPPHQNTFPPR[166.11].S sp|Q96I24|FUBP3_HUMAN 1 3237.5984 2.62 106140 20635 3 3237.600336 1080.2067 Far upstream element-binding protein 3 OS=Homo sapiens OX=9606 GN=FUBP3 PE=1 SV=2 9.73 3313.6 - 322110 - - - 0.6134 - 2.964 0.452 - 117.5 1 2 0 0.002 32 0 0 0 3.29E+07 1.25E+07 - - - 6.0785 1 221125_WJC_METTL3_EV_vs_WT_F07.20644.20644.4 1.41E-12 21/174 R.SIFGEDALANVSIEKPIHQGPDAAVTGHIR.L sp|P53618|COPB_HUMAN 1 3141.6207 0.67 106147 20644 4 3141.621171 786.4125 Coatomer subunit beta OS=Homo sapiens OX=9606 GN=COPB1 PE=1 SV=3 5.3 3314.6 - 618826 - - - 0.1464 - 4.345 0.625 - 203.6 1 2 0 0.0005 30 0 0 0 6.59E+06 9.82E+06 - - - 5.1154 1 221125_WJC_METTL3_EV_vs_WT_F07.20645.20645.3 4.22E-08 18/84 K.QQTTLTEWYSAQENSFK[136.11]PESQR[166.11].Q "sp|Q9H6S0|YTDC2_HUMAN,tr|D6RA70|D6RA70_HUMAN" 2 2675.2582 0.69 106148 20645 3 2675.26083 892.76 3'-5' RNA helicase YTHDC2 OS=Homo sapiens OX=9606 GN=YTHDC2 PE=1 SV=2 4.79 3314.8 - 541077 - - - 0.9666 - 3.767 0.566 - 243.8 1 2 0 0.0026 22 0 0 0 5.18E+06 7.51E+06 - - - 7.994 0.8816 221125_WJC_METTL3_EV_vs_WT_F07.20647.20647.3 0.00299 11/104 K.QSKPVTTPEEIAQVATISANGDKEIGN.L "sp|P10809|CH60_HUMAN,tr|A0A7I2V599|A0A7I2V599_HUMAN,tr|E7EXB4|E7EXB4_HUMAN,tr|A0A7I2YQ71|A0A7I2YQ71_HUMAN,tr|E7ESH4|E7ESH4_HUMAN,tr|A0A7I2V5M1|A0A7I2V5M1_HUMAN,tr|A0A7I2V5K3|A0A7I2V5K3_HUMAN,tr|A0A7I2V369|A0A7I2V369_HUMAN" 8 2796.4141 1.72 106150 20647 3 2796.419093 933.1453 "60 kDa heat shock protein, mitochondrial OS=Homo sapiens OX=9606 GN=HSPD1 PE=1 SV=2" 4.41 3315 - 398301 - - - 1.7741 - 2.401 0.375 - 92.2 1 1 1 0.005 27 0 0 0 1.64E+07 9.52E+06 - - - 4.7346 0.9998 221125_WJC_METTL3_EV_vs_WT_F07.20650.20650.4 0.00451 7/108 R.GVAGAHGLLC[160.03]LLSDHVDK[136.11]R[166.11].L "sp|Q9UBQ7|GRHPR_HUMAN,tr|U3KQ56|U3KQ56_HUMAN" 2 2035.0752 0.82 106153 20650 4 2035.075948 509.7761 Glyoxylate reductase\hydroxypyruvate reductase OS=Homo sapiens OX=9606 GN=GRHPR PE=1 SV=1 6.91 3315.4 - 158198 - - - 0.3685 - 1.714 0.386 - 34 1 2 0 0.0007 19 0 0 0 9.57E+05 1.17E+06 - - - 2.7678 1 221125_WJC_METTL3_EV_vs_WT_F07.20653.20653.4 1.15E-12 26/150 K.YYQHLYSIHLAEQPEDC[160.03]TMQLADHIK.F "sp|Q14203|DCTN1_HUMAN,tr|A0A804CDA6|A0A804CDA6_HUMAN,tr|E7EX90|E7EX90_HUMAN,tr|A0A7P0Z4C3|A0A7P0Z4C3_HUMAN,tr|Q6AWB1|Q6AWB1_HUMAN" 5 3202.4852 1.88 106154 20653 4 3202.481756 801.6286 Dynactin subunit 1 OS=Homo sapiens OX=9606 GN=DCTN1 PE=1 SV=3 5.21 3315.9 - 901982 - - - -1.0773 - 4.907 0.667 - 499.7 1 2 0 -0.0034 26 0 0 0 4.22E+07 2.25E+07 - - - 5.5324 1 221125_WJC_METTL3_EV_vs_WT_F07.20656.20656.4 1.04E-13 25/138 R.ATC[160.03]NNYTPQFQLRPSYSSC[160.03]FPQYR.S sp|Q5T749|KPRP_HUMAN 1 2984.3334 239.17 106157 20656 4 2984.338783 747.0906 Keratinocyte proline-rich protein OS=Homo sapiens OX=9606 GN=KPRP PE=1 SV=1 8.86 3316.1 - 2.17E+06 - - - 1.8048 - 4.434 0.713 - 301.5 1 2 0 0.0054 24 0 0 0 3.59E+07 1.50E+05 - - - 5.9085 0.9993 221125_WJC_METTL3_EV_vs_WT_F07.20660.20660.2 0.342 14-Aug R.ILELDQFK[136.11].G "sp|P12956|XRCC6_HUMAN,tr|B1AHC9|B1AHC9_HUMAN" 2 1012.5684 0.26 106161 20660 2 1012.569197 507.2915 X-ray repair cross-complementing protein 6 OS=Homo sapiens OX=9606 GN=XRCC6 PE=1 SV=2 4.37 3316.7 - 164465 - - - 0.7407 - 1.627 0.323 - 136.3 1 2 0 0.0007 8 0 0 0 9.60E+05 3.66E+06 - - - 2.8944 1 221125_WJC_METTL3_EV_vs_WT_F07.20663.20663.4 1.60E-08 27/132 R.DYEVSDSAPHLEGLAEFQENVRK.T sp|Q9HBM1|SPC25_HUMAN 1 2632.2405 3.03 106162 20663 4 2632.246193 659.0674 Kinetochore protein Spc25 OS=Homo sapiens OX=9606 GN=SPC25 PE=1 SV=1 4.35 3317.1 - 1.29E+06 - - - 2.1533 - 4.285 0.631 - 285.9 1 2 0 0.0057 23 0 0 0 5.14E+07 1.70E+07 - - - 5.1881 0.9702 221125_WJC_METTL3_EV_vs_WT_F07.20669.20669.3 0.000412 10/104 K.QSK[136.11]PVTTPEEIAQVATISANGDK[136.11]EIGN.L "sp|P10809|CH60_HUMAN,tr|A0A7I2V599|A0A7I2V599_HUMAN,tr|E7EXB4|E7EXB4_HUMAN,tr|A0A7I2YQ71|A0A7I2YQ71_HUMAN,tr|E7ESH4|E7ESH4_HUMAN,tr|A0A7I2V5M1|A0A7I2V5M1_HUMAN,tr|A0A7I2V5K3|A0A7I2V5K3_HUMAN,tr|A0A7I2V369|A0A7I2V369_HUMAN" 8 2812.4425 1.72 106168 20669 3 2812.44428 938.4881 "60 kDa heat shock protein, mitochondrial OS=Homo sapiens OX=9606 GN=HSPD1 PE=1 SV=2" 4.41 3317.9 - 307340 - - - 0.6215 - 2.444 0.453 - 70.5 1 1 1 0.0017 27 0 0 0 1.64E+07 9.52E+06 - - - 5.646 1 221125_WJC_METTL3_EV_vs_WT_F07.20670.20670.4 1.61E-06 21/90 K.RGIEKPPFELPDFIKR.T "sp|Q13435|SF3B2_HUMAN,tr|E9PPJ0|E9PPJ0_HUMAN" 2 1941.0836 0.28 106169 20670 4 1941.085742 486.2782 Splicing factor 3B subunit 2 OS=Homo sapiens OX=9606 GN=SF3B2 PE=1 SV=2 8.59 3318 - 225413 - - - 1.0942 - 4.461 0.588 - 563.3 1 2 0 0.0021 16 0 0 0 6.48E+06 2.29E+07 - - - 4.8701 0.9997 221125_WJC_METTL3_EV_vs_WT_F07.20676.20676.4 8.55E-09 22/132 R.DYEVSDSAPHLEGLAEFQENVR[166.11]K[136.11].T sp|Q9HBM1|SPC25_HUMAN 1 2650.263 3.01 106173 20676 4 2650.268759 663.573 Kinetochore protein Spc25 OS=Homo sapiens OX=9606 GN=SPC25 PE=1 SV=1 4.35 3318.7 - 1.16E+06 - - - 2.1749 - 4.194 0.364 - 165.1 1 2 0 0.0058 23 0 0 0 5.11E+07 1.70E+07 - - - 2.8571 0.8849 221125_WJC_METTL3_EV_vs_WT_F07.20683.20683.3 3.06E-07 13/100 K.NGFSSVQATQLQTTQSVEGATGSAVK.S "sp|Q14157|UBP2L_HUMAN,tr|F8W726|F8W726_HUMAN" 2 2595.2776 -1 106178 20683 3 2596.265167 866.0998 Ubiquitin-associated protein 2-like OS=Homo sapiens OX=9606 GN=UBAP2L PE=1 SV=2 6 3319.6 - 1.04E+06 - - - 380.5096 - 2.998 0.373 - 153.5 1 2 0 0.9875 26 0 0 0 0.00E+00 0.00E+00 - - - 4.951 0.9836 221125_WJC_METTL3_EV_vs_WT_F07.20687.20687.3 3.00E-07 15/100 K.NGFSSVQATQLQTTQSVEGATGSAVK[136.11].S "sp|Q14157|UBP2L_HUMAN,tr|F8W726|F8W726_HUMAN" 2 2603.2918 -1 106182 20687 3 2604.279874 868.7712 Ubiquitin-associated protein 2-like OS=Homo sapiens OX=9606 GN=UBAP2L PE=1 SV=2 6 3320.1 - 469282 - - - 379.5329 - 2.948 0.571 - 231 1 2 0 0.988 26 0 0 0 0.00E+00 0.00E+00 - - - 7.1197 1 221125_WJC_METTL3_EV_vs_WT_F07.20698.20698.4 2.12E-11 28/150 K.YYQHLYSIHLAEQPEDC[160.03]TMQLADHIK[136.11].F "sp|Q14203|DCTN1_HUMAN,tr|A0A804CDA6|A0A804CDA6_HUMAN,tr|E7EX90|E7EX90_HUMAN,tr|A0A7P0Z4C3|A0A7P0Z4C3_HUMAN,tr|Q6AWB1|Q6AWB1_HUMAN" 5 3210.4994 1.89 106188 20698 4 3210.500447 803.6321 Dynactin subunit 1 OS=Homo sapiens OX=9606 GN=DCTN1 PE=1 SV=3 5.21 3321.6 - 1.14E+06 - - - 0.3242 - 5.177 0.702 - 462.8 1 2 0 0.001 26 0 0 0 4.21E+07 2.23E+07 - - - 5.8546 0.9979 221125_WJC_METTL3_EV_vs_WT_F07.20702.20702.2 0.0231 14-Jul K.VFLENVIR.D sp|P62805|H4_HUMAN 1 988.5706 2.61 106190 20702 2 988.567491 495.2926 Histone H4 OS=Homo sapiens OX=9606 GN=H4C1 PE=1 SV=2 5.97 3322.1 - 663650 - - - -3.1106 - 1.535 0.382 - 154.1 1 2 0 -0.0031 8 0 0 0 2.29E+07 8.78E+06 - - - 3.1539 0.999 221125_WJC_METTL3_EV_vs_WT_F07.20705.20705.2 0.0107 14-Aug K.VFLENVIR[166.11].D sp|P62805|H4_HUMAN 1 998.5788 2.57 106192 20705 2 998.575867 500.2967 Histone H4 OS=Homo sapiens OX=9606 GN=H4C1 PE=1 SV=2 5.97 3322.4 - 389095 - - - -2.9732 - 1.789 0.415 - 272.2 1 2 0 -0.003 8 0 0 0 2.26E+07 8.78E+06 - - - 3.8595 0.9999 221125_WJC_METTL3_EV_vs_WT_F07.20708.20708.3 3.51E-06 17/52 K.ILLAELEQLKGQGK.S "sp|P08670|VIME_HUMAN,tr|B0YJC4|B0YJC4_HUMAN,tr|A0A1B0GTT5|A0A1B0GTT5_HUMAN" 3 1538.9032 2.15 106193 20708 3 1538.900802 513.975 Vimentin OS=Homo sapiens OX=9606 GN=VIM PE=1 SV=4 6.14 3322.8 - 378543 - - - -1.5544 - 3.274 0.457 - 412.1 1 2 1 -0.0024 14 0 0 0 7.93E+06 3.69E+06 - - - 6.7863 0.9385 221125_WJC_METTL3_EV_vs_WT_F07.20715.20715.3 0.303 12/100 R.QLLSDYGPPSLGYTQGTGNSQVPQSK[136.11].Y "sp|O14519|CDKA1_HUMAN,tr|F5GZF0|F5GZF0_HUMAN" 2 2729.3388 1.75 106197 20715 3 2729.341237 910.7869 Cyclin-dependent kinase 2-associated protein 1 OS=Homo sapiens OX=9606 GN=CDK2AP1 PE=1 SV=1 5.83 3323.7 - 458321 - - - 0.8969 - 1.388 0.132 - 25.7 1 2 0 0.0024 26 0 0 0 3.05E+07 1.75E+07 - - - 0.7653 1 221125_WJC_METTL3_EV_vs_WT_F07.20716.20716.4 1.09E-09 20/174 R.SNGETPAVDIGAADLAHAQQQQQQALQVAR.Q "sp|Q9H334|FOXP1_HUMAN,tr|G5E965|G5E965_HUMAN,tr|A0A3B3IRY1|A0A3B3IRY1_HUMAN,tr|A0A087WVT2|A0A087WVT2_HUMAN,tr|A0A3B3IRS5|A0A3B3IRS5_HUMAN,tr|A0A3B3IST0|A0A3B3IST0_HUMAN,tr|A0A3B3ISQ7|A0A3B3ISQ7_HUMAN,tr|C9J0F0|C9J0F0_HUMAN,tr|A0A3B3IU15|A0A3B3IU15_HUMAN,tr|A0A3B3IU08|A0A3B3IU08_HUMAN,tr|A0A3B3IST6|A0A3B3IST6_HUMAN" 11 3114.5443 12.03 106198 20716 4 3114.552246 779.6433 Forkhead box protein P1 OS=Homo sapiens OX=9606 GN=FOXP1 PE=1 SV=1 4.53 3323.8 - 1.11E+06 - - - 2.5667 - 3.658 0.556 - 217 1 2 0 0.008 30 0 0 0 1.49E+07 1.24E+06 - - - 4.4601 1 221125_WJC_METTL3_EV_vs_WT_F07.20717.20717.3 1.66E-17 29/116 R.SNGETPAVDIGAADLAHAQQQQQQALQVAR.Q "sp|Q9H334|FOXP1_HUMAN,tr|G5E965|G5E965_HUMAN,tr|A0A3B3IRY1|A0A3B3IRY1_HUMAN,tr|A0A087WVT2|A0A087WVT2_HUMAN,tr|A0A3B3IRS5|A0A3B3IRS5_HUMAN,tr|A0A3B3IST0|A0A3B3IST0_HUMAN,tr|A0A3B3ISQ7|A0A3B3ISQ7_HUMAN,tr|C9J0F0|C9J0F0_HUMAN,tr|A0A3B3IU15|A0A3B3IU15_HUMAN,tr|A0A3B3IU08|A0A3B3IU08_HUMAN,tr|A0A3B3IST6|A0A3B3IST6_HUMAN" 11 3114.5443 44.1 106199 20717 3 3114.539723 1039.1887 Forkhead box protein P1 OS=Homo sapiens OX=9606 GN=FOXP1 PE=1 SV=1 4.53 3324 - 1.25E+06 - - - -1.4541 - 5.503 0.759 - 670.8 1 2 0 -0.0045 30 0 0 0 3.18E+07 7.21E+05 - - - 10.9241 1 221125_WJC_METTL3_EV_vs_WT_F07.20718.20718.3 3.87E-08 13/100 R.QLLSDYGPPSLGYTQGTGNSQVPQSK.Y "sp|O14519|CDKA1_HUMAN,tr|F5GZF0|F5GZF0_HUMAN" 2 2721.3246 1.75 106200 20718 3 2721.322746 908.1155 Cyclin-dependent kinase 2-associated protein 1 OS=Homo sapiens OX=9606 GN=CDK2AP1 PE=1 SV=1 5.83 3324.1 - 936090 - - - -0.6772 - 3.102 0.532 - 69.4 1 2 0 -0.0018 26 0 0 0 3.05E+07 1.75E+07 - - - 7.0752 0.9955 221125_WJC_METTL3_EV_vs_WT_F07.20722.20722.3 0.000538 20/116 R.AAASSYNTQGAASSLGSYGAQAASYGAQSA.A sp|Q96PK6|RBM14_HUMAN 1 2767.2321 - 106201 20722 3 2767.231426 923.418 RNA-binding protein 14 OS=Homo sapiens OX=9606 GN=RBM14 PE=1 SV=2 5.57 3324.7 - 1.22E+06 - - - -0.2598 - 3.355 0.426 - 248.3 1 1 0 -0.0007 30 0 0 0 - - - - - 6.0741 0.9999 221125_WJC_METTL3_EV_vs_WT_F07.20731.20731.3 1.26E-05 Dec-44 R.AR[166.11]FEELNADLFR[166.11].G "sp|P54652|HSP72_HUMAN,sp|P11142|HSP7C_HUMAN,tr|E9PNE6|E9PNE6_HUMAN,tr|A8K7Q2|A8K7Q2_HUMAN,tr|E9PKE3|E9PKE3_HUMAN,tr|E9PN89|E9PN89_HUMAN" 6 1499.7636 0.15 106207 20731 3 1499.761507 500.9285 Heat shock-related 70 kDa protein 2 OS=Homo sapiens OX=9606 GN=HSPA2 PE=1 SV=1 4.68 3325.9 - 382112 - - - -1.3735 - 2.355 0.537 - 331.8 1 2 1 -0.0021 12 0 0 0 5.47E+06 3.60E+07 - - - 6.9007 0.9999 221125_WJC_METTL3_EV_vs_WT_F07.20741.20741.4 4.32E-12 25/138 K.DIHLDLPSNNNLVSKDTEEPLPVK.E "sp|P18583|SON_HUMAN,tr|H7C1M2|H7C1M2_HUMAN" 2 2686.3814 1.53 106212 20741 4 2686.377597 672.6026 Protein SON OS=Homo sapiens OX=9606 GN=SON PE=1 SV=4 4.43 3327.2 - 864401 - - - -1.4067 - 3.893 0.615 - 387.3 1 2 1 -0.0038 24 0 0 0 1.62E+07 1.06E+07 - - - 5.0142 0.9999 221125_WJC_METTL3_EV_vs_WT_F07.20745.20745.3 1.25E-06 16/76 K.DK[136.11]YPNLQVIGGNVVTAAQAK[136.11].N "sp|P12268|IMDH2_HUMAN,tr|A0A7I2YQK5|A0A7I2YQK5_HUMAN,tr|H0Y4R1|H0Y4R1_HUMAN,tr|A0A7I2V2T3|A0A7I2V2T3_HUMAN,tr|E7ETK5|E7ETK5_HUMAN" 5 2101.1503 0.76 106214 20745 3 2101.148667 701.3907 Inosine-5'-monophosphate dehydrogenase 2 OS=Homo sapiens OX=9606 GN=IMPDH2 PE=1 SV=2 8.5 3327.7 - 545668 - - - -0.7553 - 3.702 0.511 - 275.3 1 2 1 -0.0016 20 0 0 0 1.78E+07 2.35E+07 - - - 7.4121 0.9999 221125_WJC_METTL3_EV_vs_WT_F07.20756.20756.3 3.76E-09 21/76 K.DKYPNLQVIGGNVVTAAQAK.N "sp|P12268|IMDH2_HUMAN,tr|A0A7I2YQK5|A0A7I2YQK5_HUMAN,tr|H0Y4R1|H0Y4R1_HUMAN,tr|A0A7I2V2T3|A0A7I2V2T3_HUMAN,tr|E7ETK5|E7ETK5_HUMAN" 5 2085.1219 0.76 106219 20756 3 2085.125501 696.0479 Inosine-5'-monophosphate dehydrogenase 2 OS=Homo sapiens OX=9606 GN=IMPDH2 PE=1 SV=2 8.5 3329 - 725984 - - - 1.7491 - 3.64 0.567 - 554.4 1 2 1 0.0036 20 0 0 0 1.78E+07 2.35E+07 - - - 7.9949 0.9997 221125_WJC_METTL3_EV_vs_WT_F07.20759.20759.3 0.000163 Nov-44 R.ARFEELNADLFR.G "sp|P54652|HSP72_HUMAN,sp|P11142|HSP7C_HUMAN,tr|E9PNE6|E9PNE6_HUMAN,tr|A8K7Q2|A8K7Q2_HUMAN,tr|E9PKE3|E9PKE3_HUMAN,tr|E9PN89|E9PN89_HUMAN" 6 1479.747 0.15 106222 20759 3 1479.744903 494.2563 Heat shock-related 70 kDa protein 2 OS=Homo sapiens OX=9606 GN=HSPA2 PE=1 SV=1 4.68 3329.4 - 231240 - - - -1.4354 - 2.259 0.447 - 255.4 1 2 1 -0.0021 12 0 0 0 5.47E+06 3.62E+07 - - - 5.7819 1 221125_WJC_METTL3_EV_vs_WT_F07.20763.20763.3 6.43E-05 14/60 R.VSLDVNHFAPDELTVK.T "sp|P04792|HSPB1_HUMAN,tr|A0A6Q8PGY2|A0A6Q8PGY2_HUMAN,tr|A0A6Q8PHJ6|A0A6Q8PHJ6_HUMAN,tr|A0A6Q8PHA6|A0A6Q8PHA6_HUMAN,tr|A0A6Q8PF43|A0A6Q8PF43_HUMAN,tr|A0A6Q8PFK8|A0A6Q8PFK8_HUMAN,tr|A0A6Q8PGK1|A0A6Q8PGK1_HUMAN,tr|A0A6Q8PH65|A0A6Q8PH65_HUMAN,tr|A0A6Q8PFE7|A0A6Q8PFE7_HUMAN" 9 1782.9152 6.24 106224 20763 3 1782.91615 595.3123 Heat shock protein beta-1 OS=Homo sapiens OX=9606 GN=HSPB1 PE=1 SV=2 4.54 3329.9 - 400879 - - - 0.5244 - 2.758 0.436 - 280 1 2 0 0.0009 16 0 0 0 9.06E+06 1.45E+06 - - - 6.0038 0.9998 221125_WJC_METTL3_EV_vs_WT_F07.20767.20767.4 7.65E-07 20/84 R.TR[166.11]DELEVIHLIEEHR[166.11].L sp|P10155|RO60_HUMAN 1 1907.9968 0.92 106228 20767 4 1907.993098 478.0065 60 kDa SS-A\Ro ribonucleoprotein OS=Homo sapiens OX=9606 GN=RO60 PE=1 SV=2 4.92 3330.3 - 367384 - - - -1.9481 - 3.283 0.5 - 439 1 2 1 -0.0037 15 0 0 0 8.12E+06 8.85E+06 - - - 4.0023 1 221125_WJC_METTL3_EV_vs_WT_F07.20768.20768.4 6.81E-07 12/108 R.GLLQDDAHPTLVTYADHSK[136.11].L "sp|Q86U44|MTA70_HUMAN,tr|F5H6D8|F5H6D8_HUMAN,tr|H0YFV6|H0YFV6_HUMAN,tr|B4DTN4|B4DTN4_HUMAN" 4 2088.0367 0.001 106229 20768 4 2088.037328 523.0165 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 5.13 3330.5 - 321908 - - - 0.285 - 2.725 0.483 - 140.3 1 2 0 0.0006 19 0 0 0 0.00E+00 1.09E+07 - - - 3.769 1 221125_WJC_METTL3_EV_vs_WT_F07.20771.20771.4 2.99E-09 18/132 K.K[136.11]PALGFYDTSEENYQALDADFR[166.11]K[136.11].L sp|Q99459|CDC5L_HUMAN 1 2703.3027 1.96 106230 20771 4 2703.301858 676.8329 Cell division cycle 5-like protein OS=Homo sapiens OX=9606 GN=CDC5L PE=1 SV=2 4.44 3330.9 - 627990 - - - -0.3044 - 3.492 0.601 - 253.8 1 2 0 -0.0008 23 0 0 0 1.15E+07 5.87E+06 - - - 4.862 1 221125_WJC_METTL3_EV_vs_WT_F07.20773.20773.4 2.27E-08 30/216 R.GQPGNAYDGAGQPSAAYLSMSQGAVANANSTPPPYER.T sp|Q96PK6|RBM14_HUMAN 1 3693.6754 4.1 106232 20773 4 3693.680029 924.4261 RNA-binding protein 14 OS=Homo sapiens OX=9606 GN=RBM14 PE=1 SV=2 4.37 3331.1 - 1.20E+06 - - - 1.2527 - 4.971 0.677 - 276.4 1 2 0 0.0046 37 0 0 0 1.72E+07 4.19E+06 - - - 5.5874 1 221125_WJC_METTL3_EV_vs_WT_F07.20774.20774.4 2.77E-09 15/132 K.SWASLFHDSK[136.11]PSSSSPVAYVETK[136.11].Y sp|Q14694|UBP10_HUMAN 1 2525.2409 1 106233 20774 4 2525.246286 632.3175 Ubiquitin carboxyl-terminal hydrolase 10 OS=Homo sapiens OX=9606 GN=USP10 PE=1 SV=2 6.47 3331.3 - 749510 - - - 2.1253 - 2.856 0.571 - 110.3 1 2 0 0.0054 23 0 0 0 1.52E+07 1.52E+07 - - - 4.5345 0.9982 221125_WJC_METTL3_EV_vs_WT_F07.20778.20778.3 1.13E-07 13/112 S.LTSFGTETSNSGTLPQSSAVGSAFTQDTR[166.11].S "sp|Q8ND56|LS14A_HUMAN,tr|A0A140TA76|A0A140TA76_HUMAN,tr|K7EMZ9|K7EMZ9_HUMAN" 3 2956.3926 1.02 106237 20778 3 2956.39019 986.4715 Protein LSM14 homolog A OS=Homo sapiens OX=9606 GN=LSM14A PE=1 SV=3 4.37 3331.8 - 366211 - - - -0.8013 - 3.106 0.552 - 101.3 1 1 0 -0.0024 29 0 0 0 5.43E+06 5.30E+06 - - - 7.301 1 221125_WJC_METTL3_EV_vs_WT_F07.20783.20783.3 1.05E-16 28/144 R.GQPGNAYDGAGQPSAAYLSMSQGAVANANSTPPPYER.T sp|Q96PK6|RBM14_HUMAN 1 3693.6754 2.81 106241 20783 3 3693.676286 1232.2324 RNA-binding protein 14 OS=Homo sapiens OX=9606 GN=RBM14 PE=1 SV=2 4.37 3332.4 - 919121 - - - 0.2393 - 4.982 0.708 - 299.9 1 2 0 0.0009 37 0 0 0 1.33E+08 4.73E+07 - - - 10.1277 0.9999 221125_WJC_METTL3_EV_vs_WT_F07.20785.20785.4 6.75E-08 19/84 R.TRDELEVIHLIEEHR.L sp|P10155|RO60_HUMAN 1 1887.9803 0.92 106243 20785 4 1887.980694 473.0023 60 kDa SS-A\Ro ribonucleoprotein OS=Homo sapiens OX=9606 GN=RO60 PE=1 SV=2 4.92 3332.7 - 482042 - - - 0.2219 - 3.139 0.573 - 420.4 1 2 1 0.0004 15 0 0 0 8.12E+06 8.85E+06 - - - 4.6226 1 221125_WJC_METTL3_EV_vs_WT_F07.20788.20788.3 2.19E-14 28/108 K.LSFDSSPTSSTDGHSSYGLDSGFC[160.03]TISR.L sp|Q00587|BORG5_HUMAN 1 2967.2829 1.22 106244 20788 3 2967.287177 990.1016 Cdc42 effector protein 1 OS=Homo sapiens OX=9606 GN=CDC42EP1 PE=1 SV=1 4.41 3333.1 - 910866 - - - 1.4549 - 4.519 0.753 - 604.5 1 2 0 0.0043 28 0 0 0 3.11E+07 2.54E+07 - - - 10.404 1 221125_WJC_METTL3_EV_vs_WT_F07.20790.20790.3 3.46E-16 27/108 K.LSFDSSPTSSTDGHSSYGLDSGFC[160.03]TISR[166.11].L sp|Q00587|BORG5_HUMAN 1 2977.2911 1.22 106246 20790 3 2977.294791 993.4377 Cdc42 effector protein 1 OS=Homo sapiens OX=9606 GN=CDC42EP1 PE=1 SV=1 4.41 3333.4 - 837037 - - - 1.2296 - 4.373 0.751 - 642.2 1 2 0 0.0037 28 0 0 0 3.11E+07 2.54E+07 - - - 10.3064 0.9999 221125_WJC_METTL3_EV_vs_WT_F07.20793.20793.4 4.23E-05 18/114 K.NSDRTPLVSVLLEGPPHSGK.T "sp|P46459|NSF_HUMAN,tr|I3L0N3|I3L0N3_HUMAN" 2 2102.112 1.23 106249 20793 4 2102.114276 526.5353 Vesicle-fusing ATPase OS=Homo sapiens OX=9606 GN=NSF PE=1 SV=3 6.75 3333.7 - 292829 - - - 1.0746 - 3.482 0.55 - 241.4 1 2 1 0.0023 20 0 0 0 1.56E+07 1.26E+07 - - - 4.4297 0.9954 221125_WJC_METTL3_EV_vs_WT_F07.20794.20794.4 0.000104 18/114 K.NSDR[166.11]TPLVSVLLEGPPHSGK[136.11].T "sp|P46459|NSF_HUMAN,tr|I3L0N3|I3L0N3_HUMAN" 2 2120.1345 1.08 106250 20794 4 2120.146235 531.0409 Vesicle-fusing ATPase OS=Homo sapiens OX=9606 GN=NSF PE=1 SV=3 6.75 3333.9 - 289545 - - - 5.5412 - 3.523 0.447 - 260.3 1 2 1 0.0117 20 0 0 0 5.47E+06 5.06E+06 - - - 3.5344 0.9991 221125_WJC_METTL3_EV_vs_WT_F07.20796.20796.4 2.37E-06 12/114 K.HSNKYEGWPEALEMEGC[160.03]IPR.R "sp|P98173|FAM3A_HUMAN,tr|Q5HY75|Q5HY75_HUMAN,tr|D3DWX8|D3DWX8_HUMAN" 3 2402.0784 0.83 106252 20796 4 2402.0887 601.5269 Protein FAM3A OS=Homo sapiens OX=9606 GN=FAM3A PE=1 SV=2 4.91 3334.1 - 233173 - - - 4.3084 - 2.609 0.528 - 84.8 1 2 1 0.0103 20 0 0 0 2.07E+06 2.50E+06 - - - 4.1394 0.9999 221125_WJC_METTL3_EV_vs_WT_F07.20802.20802.4 2.61E-05 21/132 K.LQLLEEKTDEDEKTILNLENSNK.S sp|Q8IX12|CCAR1_HUMAN 1 2715.3814 4.38 106256 20802 4 2715.386879 679.8526 Cell division cycle and apoptosis regulator protein 1 OS=Homo sapiens OX=9606 GN=CCAR1 PE=1 SV=2 4.25 3334.9 - 1.03E+06 - - - 2.0049 - 3.662 0.544 - 218.6 1 2 2 0.0054 23 0 0 0 8.07E+07 1.84E+07 - - - 4.38 1 221125_WJC_METTL3_EV_vs_WT_F07.20803.20803.4 3.72E-11 29/132 K.KPALGFYDTSEENYQALDADFRK.L sp|Q99459|CDC5L_HUMAN 1 2677.266 1.95 106257 20803 4 2677.27733 670.3238 Cell division cycle 5-like protein OS=Homo sapiens OX=9606 GN=CDC5L PE=1 SV=2 4.44 3335 - 933423 - - - 4.2278 - 4.575 0.664 - 927.8 1 2 0 0.0113 23 0 0 0 1.18E+07 6.03E+06 - - - 5.495 0.9999 221125_WJC_METTL3_EV_vs_WT_F07.20805.20805.4 6.59E-07 15/96 K.QEVPSWLENMAYEHHYK.G "sp|O00571|DDX3X_HUMAN,sp|O15523|DDX3Y_HUMAN,tr|A0A2R8YFR4|A0A2R8YFR4_HUMAN,tr|A0A2R8YCW1|A0A2R8YCW1_HUMAN,tr|A0A2R8YDT5|A0A2R8YDT5_HUMAN,tr|A0A2R8Y645|A0A2R8Y645_HUMAN,tr|A0A2R8YF78|A0A2R8YF78_HUMAN,tr|A0A0D9SFB3|A0A0D9SFB3_HUMAN,tr|A0A2R8YFS5|A0A2R8YFS5_HUMAN,tr|A0A0D9SF53|A0A0D9SF53_HUMAN,tr|A0A087WVZ1|A0A087WVZ1_HUMAN,tr|A0A0J9YVQ7|A0A0J9YVQ7_HUMAN,tr|A0A2R8Y5G6|A0A2R8Y5G6_HUMAN,tr|A0A2R8Y7T2|A0A2R8Y7T2_HUMAN,tr|A0A0D9SG12|A0A0D9SG12_HUMAN,tr|F6S8Q4|F6S8Q4_HUMAN,tr|A0A2U3TZJ9|A0A2U3TZJ9_HUMAN,tr|A0A2R8Y4A4|A0A2R8Y4A4_HUMAN" 18 2159.9735 1.09 106259 20805 4 2159.978459 541.0006 ATP-dependent RNA helicase DDX3X OS=Homo sapiens OX=9606 GN=DDX3X PE=1 SV=3 5.33 3335.3 - 523491 - - - 2.3074 - 3.444 0.519 - 159.8 1 2 0 0.005 17 0 0 0 1.02E+07 9.39E+06 - - - 4.1714 1 221125_WJC_METTL3_EV_vs_WT_F07.20806.20806.4 1.83E-07 19/102 K.WKPPMIDNPSYQGIWKPR.K "sp|P27824|CALX_HUMAN,tr|A0A7P0T937|A0A7P0T937_HUMAN,tr|A0A7P0T840|A0A7P0T840_HUMAN,tr|A0A7P0TB65|A0A7P0TB65_HUMAN,tr|A0A7P0TAE9|A0A7P0TAE9_HUMAN,tr|D6RGY2|D6RGY2_HUMAN,tr|A0A7P0T8G1|A0A7P0T8G1_HUMAN,tr|A0A7P0Z4D6|A0A7P0Z4D6_HUMAN,tr|A0A7P0T9L0|A0A7P0T9L0_HUMAN" 9 2212.1252 0.9 106260 20806 4 2212.12937 554.0386 Calnexin OS=Homo sapiens OX=9606 GN=CANX PE=1 SV=2 9.7 3335.4 - 412535 - - - 1.9009 - 3.501 0.551 - 373.3 1 2 0 0.0042 18 0 0 0 5.26E+06 5.85E+06 - - - 4.45 0.9641 221125_WJC_METTL3_EV_vs_WT_F07.20807.20807.3 1.17E-05 16/120 R.AAASSYNTQGAASSLGSYGAQAASYGAQSAA.S sp|Q96PK6|RBM14_HUMAN 1 2838.2693 - 106261 20807 3 2838.275894 947.097 RNA-binding protein 14 OS=Homo sapiens OX=9606 GN=RBM14 PE=1 SV=2 5.57 3335.6 - 344682 - - - 2.3377 - 3.146 0.329 - 191.1 1 1 0 0.0066 31 0 0 0 - - - - - 4.843 0.9999 221125_WJC_METTL3_EV_vs_WT_F07.20808.20808.4 4.92E-05 Oct-84 R.HHGDVMDLQFFDQER.L "sp|Q8NFH3|NUP43_HUMAN,tr|B4E301|B4E301_HUMAN,tr|F5H0E3|F5H0E3_HUMAN,tr|B4DVD1|B4DVD1_HUMAN" 4 1872.8213 1.62 106262 20808 4 1872.826944 469.2126 Nucleoporin Nup43 OS=Homo sapiens OX=9606 GN=NUP43 PE=1 SV=1 4.64 3335.7 - 89566 - - - 2.9971 - 2.16 0.585 - 99.2 1 2 0 0.0056 15 0 0 0 1.34E+06 8.23E+05 - - - 4.5918 0.9999 221125_WJC_METTL3_EV_vs_WT_F07.20811.20811.4 9.49E-08 14/132 K.LQLLEEK[136.11]TDEDEK[136.11]TILNLENSNK[136.11].S sp|Q8IX12|CCAR1_HUMAN 1 2739.424 4.38 106263 20811 4 2739.429303 685.8633 Cell division cycle and apoptosis regulator protein 1 OS=Homo sapiens OX=9606 GN=CCAR1 PE=1 SV=2 4.25 3336.1 - 763872 - - - 1.923 - 3.162 0.537 - 99.1 1 2 2 0.0053 23 0 0 0 8.07E+07 1.84E+07 - - - 4.2716 0.9854 221125_WJC_METTL3_EV_vs_WT_F07.20812.20812.3 0.0765 14/48 L.DGIHLLDPDVVAR[166.11].F sp|Q86U44|MTA70_HUMAN 1 1428.76 0.01 106264 20812 3 1428.761963 477.2606 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 4.41 3336.2 - 457178 - - - 1.3403 - 2.796 0.341 - 410.5 1 1 0 0.0019 13 0 0 0 6.46E+04 9.72E+06 - - - 5.129 1 221125_WJC_METTL3_EV_vs_WT_F07.20813.20813.4 9.19E-09 17/96 K.QEVPSWLENMAYEHHYK[136.11].G "sp|O00571|DDX3X_HUMAN,sp|O15523|DDX3Y_HUMAN,tr|A0A2R8YFR4|A0A2R8YFR4_HUMAN,tr|A0A2R8YCW1|A0A2R8YCW1_HUMAN,tr|A0A2R8YDT5|A0A2R8YDT5_HUMAN,tr|A0A2R8Y645|A0A2R8Y645_HUMAN,tr|A0A2R8YF78|A0A2R8YF78_HUMAN,tr|A0A0D9SFB3|A0A0D9SFB3_HUMAN,tr|A0A2R8YFS5|A0A2R8YFS5_HUMAN,tr|A0A0D9SF53|A0A0D9SF53_HUMAN,tr|A0A087WVZ1|A0A087WVZ1_HUMAN,tr|A0A0J9YVQ7|A0A0J9YVQ7_HUMAN,tr|A0A2R8Y5G6|A0A2R8Y5G6_HUMAN,tr|A0A2R8Y7T2|A0A2R8Y7T2_HUMAN,tr|A0A0D9SG12|A0A0D9SG12_HUMAN,tr|F6S8Q4|F6S8Q4_HUMAN,tr|A0A2U3TZJ9|A0A2U3TZJ9_HUMAN,tr|A0A2R8Y4A4|A0A2R8Y4A4_HUMAN" 18 2167.9877 1.14 106265 20813 4 2167.991246 543.0042 ATP-dependent RNA helicase DDX3X OS=Homo sapiens OX=9606 GN=DDX3X PE=1 SV=3 5.33 3336.4 - 686311 - - - 1.6471 - 3.426 0.562 - 223.8 1 2 0 0.0036 17 0 0 0 9.62E+06 8.45E+06 - - - 4.5442 1 221125_WJC_METTL3_EV_vs_WT_F07.20814.20814.4 1.79E-08 16/96 K.HLNEIDLFHC[160.03]IDPNDSK[136.11].H "sp|Q15185|TEBP_HUMAN,tr|A0A087WYT3|A0A087WYT3_HUMAN" 2 2073.9669 0.74 106266 20814 4 2073.972731 519.499 Prostaglandin E synthase 3 OS=Homo sapiens OX=9606 GN=PTGES3 PE=1 SV=1 4.64 3336.5 - 450586 - - - 2.7922 - 2.823 0.587 - 165.7 1 2 0 0.0058 17 0 0 0 1.73E+07 2.35E+07 - - - 4.694 0.9996 221125_WJC_METTL3_EV_vs_WT_F07.20815.20815.3 1.90E-09 19/72 K.RLDEELEDAEKNLGESEIR.D "sp|Q15008|PSMD6_HUMAN,tr|C9J0E9|C9J0E9_HUMAN,tr|C9J7B7|C9J7B7_HUMAN" 3 2244.087 0.17 106267 20815 3 2244.095112 749.0363 26S proteasome non-ATPase regulatory subunit 6 OS=Homo sapiens OX=9606 GN=PSMD6 PE=1 SV=1 4.17 3336.6 - 589414 - - - 3.622 - 3.305 0.56 - 604.3 1 2 1 0.0081 19 0 0 0 1.51E+06 8.87E+06 - - - 7.7181 0.9997 221125_WJC_METTL3_EV_vs_WT_F07.20816.20816.3 2.79E-07 14/96 R.KSSVDLNQVSMLSPAALSPASSSQR.T "sp|Q8NEM7|SP20H_HUMAN,tr|B4E2D5|B4E2D5_HUMAN,tr|R4GND2|R4GND2_HUMAN,tr|H7C5F9|H7C5F9_HUMAN,tr|F6S7C4|F6S7C4_HUMAN" 5 2559.2963 0.27 106268 20816 3 2559.307922 854.106 Transcription factor SPT20 homolog OS=Homo sapiens OX=9606 GN=SUPT20H PE=1 SV=2 8.75 3336.7 - 237416 - - - 4.5544 - 3.403 0.488 - 136.6 1 2 0 0.0117 25 0 0 0 5.32E+06 1.99E+07 - - - 6.795 1 221125_WJC_METTL3_EV_vs_WT_F07.20819.20819.3 2.34E-14 26/88 K.LQLLEEKTDEDEKTILNLENSNK.S sp|Q8IX12|CCAR1_HUMAN 1 2715.3814 6.03 106269 20819 3 2715.386874 906.1344 Cell division cycle and apoptosis regulator protein 1 OS=Homo sapiens OX=9606 GN=CCAR1 PE=1 SV=2 4.25 3337.1 - 1.61E+06 - - - 2.003 - 5.057 0.679 - 590.6 1 2 2 0.0054 23 0 0 0 2.09E+07 3.46E+06 - - - 9.9109 0.9999 221125_WJC_METTL3_EV_vs_WT_F07.20820.20820.4 6.11E-05 20/162 K.EMEPLGWIHTQPNESPQLSPQDVTTHAK.L sp|Q6P2Q9|PRP8_HUMAN 1 3169.5139 1.6 106270 20820 4 3169.512097 793.3857 Pre-mRNA-processing-splicing factor 8 OS=Homo sapiens OX=9606 GN=PRPF8 PE=1 SV=2 4.8 3337.3 - 1.23E+06 - - - -0.5572 - 3.663 0.451 - 164.4 1 2 0 -0.0018 28 0 0 0 1.60E+07 1.00E+07 - - - 3.5541 1 221125_WJC_METTL3_EV_vs_WT_F07.20821.20821.3 3.43E-06 23/64 K.HLNEIDLFHC[160.03]IDPNDSK.H "sp|Q15185|TEBP_HUMAN,tr|A0A087WYT3|A0A087WYT3_HUMAN" 2 2065.9527 0.55 106271 20821 3 2065.958085 689.6582 Prostaglandin E synthase 3 OS=Homo sapiens OX=9606 GN=PTGES3 PE=1 SV=1 4.64 3337.4 - 736959 - - - 2.5872 - 4.347 0.601 - 745.3 1 2 0 0.0053 17 0 0 0 3.98E+07 7.26E+07 - - - 8.9514 1 221125_WJC_METTL3_EV_vs_WT_F07.20823.20823.4 1.27E-09 24/186 K.VGGTNLGAPGAFGQSPFSQPPAPPHQNTFPPR[166.11].S sp|Q96I24|FUBP3_HUMAN 1 3237.5984 2.29 106273 20823 4 3237.60781 810.4069 Far upstream element-binding protein 3 OS=Homo sapiens OX=9606 GN=FUBP3 PE=1 SV=2 9.73 3337.7 - 444316 - - - 2.9219 - 4.092 0.579 - 212.9 1 2 0 0.0095 32 0 0 0 7.68E+07 3.35E+07 - - - 4.6884 0.9999 221125_WJC_METTL3_EV_vs_WT_F07.20825.20825.3 5.61E-06 20/88 K.LQLLEEK[136.11]TDEDEK[136.11]TILNLENSNK[136.11].S sp|Q8IX12|CCAR1_HUMAN 1 2739.424 6.03 106275 20825 3 2739.428003 914.1486 Cell division cycle and apoptosis regulator protein 1 OS=Homo sapiens OX=9606 GN=CCAR1 PE=1 SV=2 4.25 3337.9 - 421807 - - - 1.4485 - 3.63 0.542 - 349.4 1 2 2 0.004 23 0 0 0 2.09E+07 3.46E+06 - - - 7.6061 0.9999 221125_WJC_METTL3_EV_vs_WT_F07.20828.20828.4 2.89E-08 19/108 K.ER[166.11]VEAVNMAEGIIHDTETK[136.11].M "sp|P38646|GRP75_HUMAN,tr|A0A7I2V2S7|A0A7I2V2S7_HUMAN,tr|A0A7I2V2G2|A0A7I2V2G2_HUMAN,tr|A0A7I2V3F7|A0A7I2V3F7_HUMAN,tr|A0A7I2YQB2|A0A7I2YQB2_HUMAN,tr|D6RCD7|D6RCD7_HUMAN" 6 2159.0648 0.41 106276 20828 4 2159.066345 540.7735 "Stress-70 protein, mitochondrial OS=Homo sapiens OX=9606 GN=HSPA9 PE=1 SV=2" 4.57 3338.3 - 1.88E+06 - - - 0.7374 - 3.402 0.527 - 333.8 1 2 1 0.0016 19 0 0 0 3.70E+08 9.09E+08 - - - 4.2267 1 221125_WJC_METTL3_EV_vs_WT_F07.20829.20829.3 1.73E-12 28/72 K.ER[166.11]VEAVNMAEGIIHDTETK[136.11].M "sp|P38646|GRP75_HUMAN,tr|A0A7I2V2S7|A0A7I2V2S7_HUMAN,tr|A0A7I2V2G2|A0A7I2V2G2_HUMAN,tr|A0A7I2V3F7|A0A7I2V3F7_HUMAN,tr|A0A7I2YQB2|A0A7I2YQB2_HUMAN,tr|D6RCD7|D6RCD7_HUMAN" 6 2159.0648 0.4 106277 20829 3 2159.067327 720.6955 "Stress-70 protein, mitochondrial OS=Homo sapiens OX=9606 GN=HSPA9 PE=1 SV=2" 4.57 3338.4 - 1.72E+06 - - - 1.1922 - 5.51 0.631 - 1033.1 1 2 1 0.0026 19 0 0 0 4.12E+08 1.03E+09 - - - 9.767 1 221125_WJC_METTL3_EV_vs_WT_F07.20830.20830.3 2.52E-09 20/72 R.TSQNSELNNMQDLVEDYKK.K sp|P35908|K22E_HUMAN 1 2255.0376 -1 106278 20830 3 2256.027467 752.6865 "Keratin, type II cytoskeletal 2 epidermal OS=Homo sapiens OX=9606 GN=KRT2 PE=1 SV=2" 4.32 3338.5 - 1.68E+06 - - - 438.9621 - 3.704 0.635 - 514.7 1 2 0 0.9899 19 0 0 0 0.00E+00 0.00E+00 - - - 8.5624 0.9998 221125_WJC_METTL3_EV_vs_WT_F07.20835.20835.3 0.0111 18/52 R.NKLNDLEEALQQAK.E sp|P35908|K22E_HUMAN 1 1612.842 999 106281 20835 3 1612.844141 538.6213 "Keratin, type II cytoskeletal 2 epidermal OS=Homo sapiens OX=9606 GN=KRT2 PE=1 SV=2" 4.68 3339.2 - 4.14E+06 - - - 1.2965 - 3.535 0.397 - 581.5 1 2 1 0.0021 14 0 0 0 8.11E+07 0.00E+00 - - - 6.3213 1 221125_WJC_METTL3_EV_vs_WT_F07.20836.20836.3 1.42E-12 36/72 K.ERVEAVNMAEGIIHDTETK.M "sp|P38646|GRP75_HUMAN,tr|A0A7I2V2S7|A0A7I2V2S7_HUMAN,tr|A0A7I2V2G2|A0A7I2V2G2_HUMAN,tr|A0A7I2V3F7|A0A7I2V3F7_HUMAN,tr|A0A7I2YQB2|A0A7I2YQB2_HUMAN,tr|D6RCD7|D6RCD7_HUMAN" 6 2141.0423 0.4 106282 20836 3 2141.043567 714.688 "Stress-70 protein, mitochondrial OS=Homo sapiens OX=9606 GN=HSPA9 PE=1 SV=2" 4.57 3339.3 - 1.38E+06 - - - 0.5997 - 6.186 0.634 - 1998.5 1 2 1 0.0013 19 0 0 0 4.12E+08 1.03E+09 - - - 10.0851 0.9999 221125_WJC_METTL3_EV_vs_WT_F07.20837.20837.4 8.96E-08 29/186 K.VGGTNLGAPGAFGQSPFSQPPAPPHQNTFPPR.S sp|Q96I24|FUBP3_HUMAN 1 3227.5901 2.27 106283 20837 4 3227.597206 807.9048 Far upstream element-binding protein 3 OS=Homo sapiens OX=9606 GN=FUBP3 PE=1 SV=2 9.73 3339.4 - 1.38E+06 - - - 2.2078 - 4.384 0.496 - 273.8 1 2 0 0.0071 32 0 0 0 7.48E+07 3.30E+07 - - - 3.9875 0.9999 221125_WJC_METTL3_EV_vs_WT_F07.20842.20842.4 6.45E-09 13/102 R.HYEMQQQQFQHLYQEWER[166.11].E "sp|P49750|YLPM1_HUMAN,tr|F8VU51|F8VU51_HUMAN" 2 2517.1159 1.91 106288 20842 4 2517.121726 630.2863 YLP motif-containing protein 1 OS=Homo sapiens OX=9606 GN=YLPM1 PE=1 SV=4 5.33 3340.1 - 353598 - - - 2.2959 - 2.986 0.521 - 179.1 1 2 0 0.0058 18 0 0 0 5.14E+06 2.69E+06 - - - 4.1339 0.9999 221125_WJC_METTL3_EV_vs_WT_F07.20845.20845.4 7.30E-06 16/72 R.K[136.11]IEEIK[136.11]DFLLTAR[166.11].R "sp|P63173|RL38_HUMAN,tr|J3KT73|J3KT73_HUMAN,tr|J3QL01|J3QL01_HUMAN,tr|J3KSP2|J3KSP2_HUMAN" 4 1600.9399 1.18 106291 20845 4 1600.941636 401.2422 60S ribosomal protein L38 OS=Homo sapiens OX=9606 GN=RPL38 PE=1 SV=2 6.18 3340.5 - 232107 - - - 1.1075 - 2.746 0.491 - 236.3 1 2 1 0.0018 13 0 0 0 8.74E+07 7.43E+07 - - - 3.8737 1 221125_WJC_METTL3_EV_vs_WT_F07.20847.20847.3 4.17E-08 20/124 K.VGGTNLGAPGAFGQSPFSQPPAPPHQNTFPPR.S sp|Q96I24|FUBP3_HUMAN 1 3227.5901 4.39 106292 20847 3 3227.591959 1076.8706 Far upstream element-binding protein 3 OS=Homo sapiens OX=9606 GN=FUBP3 PE=1 SV=2 9.73 3340.8 - 915670 - - - 0.5822 - 3.314 0.622 - 207 1 2 0 0.0019 32 0 0 0 6.28E+07 1.43E+07 - - - 8.2307 1 221125_WJC_METTL3_EV_vs_WT_F07.20849.20849.3 4.88E-07 20/48 R.K[136.11]IEEIK[136.11]DFLLTAR[166.11].R "sp|P63173|RL38_HUMAN,tr|J3KT73|J3KT73_HUMAN,tr|J3QL01|J3QL01_HUMAN,tr|J3KSP2|J3KSP2_HUMAN" 4 1600.9399 1.17 106293 20849 3 1600.941212 534.6539 60S ribosomal protein L38 OS=Homo sapiens OX=9606 GN=RPL38 PE=1 SV=2 6.18 3341 - 6.39E+06 - - - 0.8426 - 3.247 0.631 - 563 1 2 1 0.0013 13 0 0 0 4.10E+08 3.51E+08 - - - 8.7678 0.9999 221125_WJC_METTL3_EV_vs_WT_F07.20850.20850.3 1.24E-06 21/48 R.KIEEIKDFLLTAR.R "sp|P63173|RL38_HUMAN,tr|J3KT73|J3KT73_HUMAN,tr|J3QL01|J3QL01_HUMAN,tr|J3KSP2|J3KSP2_HUMAN" 4 1574.9032 1.17 106294 20850 3 1574.905846 525.975 60S ribosomal protein L38 OS=Homo sapiens OX=9606 GN=RPL38 PE=1 SV=2 6.18 3341.1 - 4.94E+06 - - - 1.6839 - 3.109 0.536 - 630 1 2 1 0.0027 13 0 0 0 4.10E+08 3.51E+08 - - - 7.5906 0.9998 221125_WJC_METTL3_EV_vs_WT_F07.20851.20851.4 9.14E-08 21/108 K.GLEEITVHNKDEVYQILEK.G "sp|P52732|KIF11_HUMAN,tr|A0A7I2YQY4|A0A7I2YQY4_HUMAN,tr|A0A7I2V3A9|A0A7I2V3A9_HUMAN,tr|A0A7I2V3V3|A0A7I2V3V3_HUMAN" 4 2256.1638 6.84 106295 20851 4 2256.167808 565.0482 Kinesin-like protein KIF11 OS=Homo sapiens OX=9606 GN=KIF11 PE=1 SV=2 4.57 3341.2 - 2.57E+06 - - - 1.7862 - 3.739 0.509 - 432.4 1 2 1 0.004 19 0 0 0 8.03E+07 1.17E+07 - - - 4.1013 0.9999 221125_WJC_METTL3_EV_vs_WT_F07.20853.20853.4 1.41E-07 21/210 R.SVGDGETVEFDVVEGEK[136.11]GAEAANVTGPGGVPVQGSK[136.11].Y "sp|P67809|YBOX1_HUMAN,tr|H0Y449|H0Y449_HUMAN" 2 3487.6926 0.71 106297 20853 4 3487.691876 872.9304 Y-box-binding protein 1 OS=Homo sapiens OX=9606 GN=YBX1 PE=1 SV=3 4 3341.5 - 1.28E+06 - - - -0.1938 - 3.091 0.625 - 104.2 1 2 1 -0.0007 36 0 0 0 1.12E+07 1.57E+07 - - - 4.9985 1 221125_WJC_METTL3_EV_vs_WT_F07.20854.20854.3 7.69E-16 27/144 R.GQPGNAYDGAGQPSAAYLSMSQGAVANANSTPPPYER[166.11].T sp|Q96PK6|RBM14_HUMAN 1 3703.6837 2.81 106298 20854 3 3703.68204 1235.5685 RNA-binding protein 14 OS=Homo sapiens OX=9606 GN=RBM14 PE=1 SV=2 4.37 3341.6 - 1.19E+06 - - - -0.4406 - 4.976 0.738 - 257 1 2 0 -0.0016 37 0 0 0 1.31E+08 4.66E+07 - - - 10.4592 1 221125_WJC_METTL3_EV_vs_WT_F07.20855.20855.3 2.55E-11 23/140 R.SVGDGETVEFDVVEGEK[136.11]GAEAANVTGPGGVPVQGSK[136.11].Y "sp|P67809|YBOX1_HUMAN,tr|H0Y449|H0Y449_HUMAN" 2 3487.6926 1.36 106299 20855 3 3487.696359 1163.5715 Y-box-binding protein 1 OS=Homo sapiens OX=9606 GN=YBX1 PE=1 SV=3 4 3341.7 - 919174 - - - 1.0916 - 3.514 0.703 - 170.6 1 2 1 0.0038 36 0 0 0 1.63E+07 1.20E+07 - - - 9.268 1 221125_WJC_METTL3_EV_vs_WT_F07.20859.20859.2 1.38E-05 17/24 R.KIEEIKDFLLTAR.R "sp|P63173|RL38_HUMAN,tr|J3KT73|J3KT73_HUMAN,tr|J3QL01|J3QL01_HUMAN,tr|J3KSP2|J3KSP2_HUMAN" 4 1574.9032 1.6 106301 20859 2 1574.900128 788.4589 60S ribosomal protein L38 OS=Homo sapiens OX=9606 GN=RPL38 PE=1 SV=2 6.18 3342.2 - 665390 - - - -1.9468 - 3.532 0.561 - 1109 1 2 1 -0.0031 13 0 0 0 3.29E+07 2.05E+07 - - - 6.4222 1 221125_WJC_METTL3_EV_vs_WT_F07.20860.20860.3 2.44E-10 18/64 K.HLNEIDLFHC[160.03]IDPNDSK[136.11].H "sp|Q15185|TEBP_HUMAN,tr|A0A087WYT3|A0A087WYT3_HUMAN" 2 2073.9669 0.55 106302 20860 3 2073.965398 692.3296 Prostaglandin E synthase 3 OS=Homo sapiens OX=9606 GN=PTGES3 PE=1 SV=1 4.64 3342.3 - 3.07E+06 - - - -0.7435 - 3.433 0.661 - 401.9 1 2 0 -0.0015 17 0 0 0 3.98E+07 7.22E+07 - - - 9.0251 0.9999 221125_WJC_METTL3_EV_vs_WT_F07.20878.20878.4 7.65E-09 20/108 K.ERVEAVNMAEGIIHDTETK.M "sp|P38646|GRP75_HUMAN,tr|A0A7I2V2S7|A0A7I2V2S7_HUMAN,tr|A0A7I2V2G2|A0A7I2V2G2_HUMAN,tr|A0A7I2V3F7|A0A7I2V3F7_HUMAN,tr|A0A7I2YQB2|A0A7I2YQB2_HUMAN,tr|D6RCD7|D6RCD7_HUMAN" 6 2141.0423 0.41 106313 20878 4 2141.037114 536.2678 "Stress-70 protein, mitochondrial OS=Homo sapiens OX=9606 GN=HSPA9 PE=1 SV=2" 4.57 3344.4 - 9.59E+06 - - - -2.4142 - 3.729 0.603 - 288 1 2 1 -0.0052 19 0 0 0 3.70E+08 9.10E+08 - - - 4.9183 0.9998 221125_WJC_METTL3_EV_vs_WT_F07.20881.20881.4 7.83E-05 16/72 R.KIEEIKDFLLTAR.R "sp|P63173|RL38_HUMAN,tr|J3KT73|J3KT73_HUMAN,tr|J3QL01|J3QL01_HUMAN,tr|J3KSP2|J3KSP2_HUMAN" 4 1574.9032 1.18 106316 20881 4 1574.904325 394.7331 60S ribosomal protein L38 OS=Homo sapiens OX=9606 GN=RPL38 PE=1 SV=2 6.18 3344.7 - 3.20E+06 - - - 0.7181 - 2.231 0.483 - 151.8 1 2 1 0.0011 13 0 0 0 8.74E+07 7.43E+07 - - - 3.7272 1 221125_WJC_METTL3_EV_vs_WT_F07.20911.20911.4 9.49E-15 28/144 K.LEHLSVSHNNLTTLHGELSSLPSLR[166.11].A "sp|Q13045|FLII_HUMAN,tr|J3KS54|J3KS54_HUMAN,tr|K7EP37|K7EP37_HUMAN,tr|K7EP27|K7EP27_HUMAN" 4 2763.4543 0.88 106326 20911 4 2763.442189 691.8709 Protein flightless-1 homolog OS=Homo sapiens OX=9606 GN=FLII PE=1 SV=2 6.27 3348.9 - 1.39E+06 - - - -4.3865 - 4.709 0.699 - 468.6 1 2 0 -0.0121 25 0 0 0 3.61E+07 4.11E+07 - - - 5.7997 0.9956 221125_WJC_METTL3_EV_vs_WT_F07.20922.20922.4 7.10E-05 11/150 K.QLPDK[136.11]WQHDLFDSGFGGGAGVETGGK[136.11].L "sp|Q86V81|THOC4_HUMAN,tr|E9PB61|E9PB61_HUMAN" 2 2718.3009 0.85 106329 20922 4 2718.29505 680.5825 THO complex subunit 4 OS=Homo sapiens OX=9606 GN=ALYREF PE=1 SV=3 4.66 3350.6 - 898150 - - - -2.1499 - 2.352 0.313 - 63.5 1 2 1 -0.0058 26 0 0 0 6.10E+06 7.21E+06 - - - 2.2185 0.9999 221125_WJC_METTL3_EV_vs_WT_F07.20930.20930.4 2.15E-07 20/150 K.AMEEMNGKDLEGENIEIVFAKPPDQK.R "sp|O60506|HNRPQ_HUMAN,tr|A0A7I2YQV8|A0A7I2YQV8_HUMAN,tr|A0A7I2YQN2|A0A7I2YQN2_HUMAN,tr|A0A7I2V4Z0|A0A7I2V4Z0_HUMAN,tr|B7Z645|B7Z645_HUMAN,tr|A0A7I2V2F2|A0A7I2V2F2_HUMAN,tr|A0A7I2V346|A0A7I2V346_HUMAN,tr|A0A7I2V309|A0A7I2V309_HUMAN" 8 2931.3994 0.92 106333 20930 4 2931.398874 733.8571 Heterogeneous nuclear ribonucleoprotein Q OS=Homo sapiens OX=9606 GN=SYNCRIP PE=1 SV=2 4.25 3351.5 - 751886 - - - -0.1828 - 3.121 0.575 - 154.3 1 2 1 -0.0005 26 0 0 0 5.35E+07 5.80E+07 - - - 4.5897 1 221125_WJC_METTL3_EV_vs_WT_F07.20935.20935.4 8.78E-11 30/144 K.LEHLSVSHNNLTTLHGELSSLPSLR.A "sp|Q13045|FLII_HUMAN,tr|J3KS54|J3KS54_HUMAN,tr|K7EP37|K7EP37_HUMAN,tr|K7EP27|K7EP27_HUMAN" 4 2753.446 0.88 106336 20935 4 2753.440155 689.3688 Protein flightless-1 homolog OS=Homo sapiens OX=9606 GN=FLII PE=1 SV=2 6.27 3352.2 - 1.30E+06 - - - -2.1377 - 4.52 0.653 - 605.3 1 2 0 -0.0059 25 0 0 0 3.61E+07 4.12E+07 - - - 5.388 1 221125_WJC_METTL3_EV_vs_WT_F07.20937.20937.4 2.14E-09 16/120 K.DGNVLLHEMQIQHPTASLIAK[136.11].V sp|P40227|TCPZ_HUMAN 1 2322.2246 0.36 106337 20937 4 2322.220988 581.5634 T-complex protein 1 subunit zeta OS=Homo sapiens OX=9606 GN=CCT6A PE=1 SV=3 5.99 3352.4 - 1.55E+06 - - - -1.5343 - 3.133 0.588 - 166.5 1 2 0 -0.0036 21 0 0 0 1.08E+07 3.02E+07 - - - 4.7206 1 221125_WJC_METTL3_EV_vs_WT_F07.20945.20945.3 2.66E-10 16/88 R.SLETEITNGINLNSDTAEHPGTR.L "sp|Q92547|TOPB1_HUMAN,tr|A0A2R8YD63|A0A2R8YD63_HUMAN" 2 2468.1779 0.83 106342 20945 3 2468.177364 823.7333 DNA topoisomerase 2-binding protein 1 OS=Homo sapiens OX=9606 GN=TOPBP1 PE=1 SV=3 4.4 3353.4 - 523529 - - - -0.2273 - 3.5 0.602 - 197.2 1 2 0 -0.0006 23 0 0 0 9.11E+06 1.10E+07 - - - 8.1905 1 221125_WJC_METTL3_EV_vs_WT_F07.20948.20948.3 5.73E-12 19/80 K.DGNVLLHEMQIQHPTASLIAK[136.11].V sp|P40227|TCPZ_HUMAN 1 2322.2246 0.32 106345 20948 3 2322.225401 775.0821 T-complex protein 1 subunit zeta OS=Homo sapiens OX=9606 GN=CCT6A PE=1 SV=3 5.99 3353.8 - 477269 - - - 0.366 - 3.802 0.623 - 360.6 1 2 0 0.0008 21 0 0 0 2.55E+06 8.01E+06 - - - 8.6875 1 221125_WJC_METTL3_EV_vs_WT_F07.20959.20959.3 1.94E-06 16/68 R.QEQVTAAVAHAVEQQMQK.L "sp|Q8IWX8|CHERP_HUMAN,tr|J3QK89|J3QK89_HUMAN" 2 1994.9844 1.28 106351 20959 3 1994.987914 666.0021 Calcium homeostasis endoplasmic reticulum protein OS=Homo sapiens OX=9606 GN=CHERP PE=1 SV=3 5.4 3355.2 - 431705 - - - 1.7744 - 3.232 0.541 - 286.9 1 2 0 0.0035 18 0 0 0 9.91E+06 7.74E+06 - - - 7.4918 1 221125_WJC_METTL3_EV_vs_WT_F07.20963.20963.3 1.61E-12 22/92 K.EIYGINFSPNGYHIATGSGDNTC[160.03]K[136.11].V sp|O43172|PRP4_HUMAN 1 2622.19 2.94 106353 20963 3 2622.189445 875.0706 U4\U6 small nuclear ribonucleoprotein Prp4 OS=Homo sapiens OX=9606 GN=PRPF4 PE=1 SV=2 5.32 3355.8 - 780230 - - - -0.2178 - 3.915 0.676 - 436.6 1 2 0 -0.0006 24 0 0 0 1.04E+08 3.54E+07 - - - 9.2465 0.9645 221125_WJC_METTL3_EV_vs_WT_F07.20965.20965.2 0.0538 12-Jun R.LLLLLLL.P "sp|P07949|RET_HUMAN,sp|A0A075B6N2|TVBT1_HUMAN,sp|Q9NYZ4|SIGL8_HUMAN,sp|Q6ZSJ9|SHSA6_HUMAN,sp|Q96PQ1|SIG12_HUMAN,sp|P43307|SSRA_HUMAN,sp|Q96A98|TIP39_HUMAN,sp|P04278|SHBG_HUMAN,sp|P08138|TNR16_HUMAN,sp|Q76KP1|B4GN4_HUMAN,sp|Q76KP1|B4GN4_HUMAN,sp|Q9Y5H6|PCDA8_HUMAN,sp|P16066|ANPRA_HUMAN,sp|A6NKQ9|CGB1_HUMAN,sp|P32297|ACHA3_HUMAN,sp|P02747|C1QC_HUMAN,sp|O75899|GABR2_HUMAN,sp|Q9H4B8|DPEP3_HUMAN,sp|O75882|ATRN_HUMAN,sp|O15354|GPR37_HUMAN,sp|A0A1B0GTW7|LMLN2_HUMAN,sp|Q96AG4|LRC59_HUMAN,sp|Q9HC10|OTOF_HUMAN,sp|Q9HC10|OTOF_HUMAN,sp|Q9HC10|OTOF_HUMAN,sp|Q5SZK8|FREM2_HUMAN,sp|Q9NX52|RHBL2_HUMAN,sp|Q9UN74|PCDA4_HUMAN,tr|C9JYL6|C9JYL6_HUMAN,tr|A0A5F9ZHR6|A0A5F9ZHR6_HUMAN,tr|A0A3B3IRT8|A0A3B3IRT8_HUMAN,tr|Q9BTX6|Q9BTX6_HUMAN,tr|E9PAL7|E9PAL7_HUMAN,tr|M0QYF3|M0QYF3_HUMAN,tr|A0A5B4|A0A5B4_HUMAN,tr|C9IZQ1|C9IZQ1_HUMAN,tr|C9JBX5|C9JBX5_HUMAN,tr|C9J3L8|C9J3L8_HUMAN,tr|A0A5F9ZHY0|A0A5F9ZHY0_HUMAN,tr|D6RA20|D6RA20_HUMAN,tr|C9J5W0|C9J5W0_HUMAN,tr|A0A5F9ZHB7|A0A5F9ZHB7_HUMAN,tr|C9JT30|C9JT30_HUMAN,tr|A0A087WSW8|A0A087WSW8_HUMAN,tr|I3L0M1|I3L0M1_HUMAN,tr|A0A5F9ZHB4|A0A5F9ZHB4_HUMAN,tr|I3L4D0|I3L4D0_HUMAN,tr|A0A2U3TZT7|A0A2U3TZT7_HUMAN,tr|A0A2R8Y3T5|A0A2R8Y3T5_HUMAN" 49 809.599 - 106355 20965 2 809.599274 405.8068 Proto-oncogene tyrosine-protein kinase receptor Ret OS=Homo sapiens OX=9606 GN=RET PE=1 SV=3 5.52 3356 - 113546 - - - 0.3224 - 1.299 0.405 - 160.6 1 1 0 0.0003 7 0 0 0 - - - - - 2.8611 1 221125_WJC_METTL3_EV_vs_WT_F07.20968.20968.3 1.36E-08 21/92 K.EIYGINFSPNGYHIATGSGDNTC[160.03]K.V sp|O43172|PRP4_HUMAN 1 2614.1758 2.94 106356 20968 3 2614.179056 872.3992 U4\U6 small nuclear ribonucleoprotein Prp4 OS=Homo sapiens OX=9606 GN=PRPF4 PE=1 SV=2 5.32 3356.4 - 2.63E+06 - - - 1.2394 - 3.83 0.669 - 331.9 1 2 0 0.0032 24 0 0 0 1.04E+08 3.54E+07 - - - 9.1167 0.9999 221125_WJC_METTL3_EV_vs_WT_F07.20970.20970.4 2.86E-09 19/120 K.NLPQDSNC[160.03]QEVHDLLKDYDLK.Y sp|Q9HCJ3|RAVR2_HUMAN 1 2543.1962 1.9 106357 20970 4 2543.201629 636.8063 Ribonucleoprotein PTB-binding 2 OS=Homo sapiens OX=9606 GN=RAVER2 PE=1 SV=2 4.35 3356.6 - 952759 - - - 2.128 - 3.068 0.603 - 145.3 1 2 1 0.0054 21 0 0 0 9.01E+07 4.75E+07 - - - 4.8437 1 221125_WJC_METTL3_EV_vs_WT_F07.20972.20972.3 1.42E-16 28/88 K.ARENPSEEAQNLVEFTDEEGYGR.Y sp|Q12874|SF3A3_HUMAN 1 2639.1736 3.61 106359 20972 3 2639.178546 880.7318 Splicing factor 3A subunit 3 OS=Homo sapiens OX=9606 GN=SF3A3 PE=1 SV=1 4.06 3356.9 - 2.22E+06 - - - 1.8862 - 5.57 0.752 - 1165.8 1 2 1 0.005 23 0 0 0 1.24E+08 3.43E+07 - - - 10.9516 1 221125_WJC_METTL3_EV_vs_WT_F07.20979.20979.3 3.20E-16 24/88 K.AR[166.11]ENPSEEAQNLVEFTDEEGYGR[166.11].Y sp|Q12874|SF3A3_HUMAN 1 2659.1901 3.45 106364 20979 3 2659.192043 887.404 Splicing factor 3A subunit 3 OS=Homo sapiens OX=9606 GN=SF3A3 PE=1 SV=1 4.06 3357.8 - 564245 - - - 0.7277 - 5.18 0.73 - 888.9 1 2 1 0.0019 23 0 0 0 1.24E+08 3.59E+07 - - - 10.5369 1 221125_WJC_METTL3_EV_vs_WT_F07.20980.20980.3 6.07E-06 19/124 K.VGGTNLGAPGAFGQSPFSQPPAPPHQNTFPPR[166.11].S sp|Q96I24|FUBP3_HUMAN 1 3237.5984 5 106365 20980 3 3237.599346 1080.2067 Far upstream element-binding protein 3 OS=Homo sapiens OX=9606 GN=FUBP3 PE=1 SV=2 9.73 3357.9 - 227557 - - - 0.3076 - 2.989 0.624 - 195.4 1 2 0 0.001 32 0 0 0 4.37E+07 8.74E+06 - - - 8.0158 1 221125_WJC_METTL3_EV_vs_WT_F07.20983.20983.3 8.63E-12 20/64 L.HDDEVTVTEDK[136.11]INALIK[136.11].A sp|P05386|RLA1_HUMAN 1 1955.0182 1.48 106366 20983 3 1955.023243 652.68 60S acidic ribosomal protein P1 OS=Homo sapiens OX=9606 GN=RPLP1 PE=1 SV=1 4.43 3358.3 - 446679 - - - 2.5611 - 3.544 0.62 - 566.7 1 1 1 0.005 17 0 0 0 5.30E+07 3.59E+07 - - - 8.6474 0.9155 221125_WJC_METTL3_EV_vs_WT_F07.20984.20984.4 0.0224 12/114 A.TISANGDK[136.11]EIGNIISDAMK[136.11]K[136.11].V "sp|P10809|CH60_HUMAN,tr|A0A7I2V599|A0A7I2V599_HUMAN,tr|E7EXB4|E7EXB4_HUMAN,tr|A0A7I2YQ71|A0A7I2YQ71_HUMAN,tr|E7ESH4|E7ESH4_HUMAN,tr|A0A7I2V5M1|A0A7I2V5M1_HUMAN,tr|A0A7I2V5K3|A0A7I2V5K3_HUMAN,tr|A0A7I2V369|A0A7I2V369_HUMAN" 8 2128.126 1.29 106367 20984 4 2128.129212 533.0388 "60 kDa heat shock protein, mitochondrial OS=Homo sapiens OX=9606 GN=HSPD1 PE=1 SV=2" 5.79 3358.5 - 614698 - - - 1.5004 - 2.016 0.396 - 49.1 1 1 1 0.0032 20 0 0 0 6.13E+07 4.77E+07 - - - 2.9063 1 221125_WJC_METTL3_EV_vs_WT_F07.20985.20985.4 1.57E-09 22/162 K.GPHLVQSDGTVPFWAHAGNAIPSSDQIR[166.11].V sp|P49257|LMAN1_HUMAN 1 2966.4663 1.83 106368 20985 4 2966.468891 742.6238 Protein ERGIC-53 OS=Homo sapiens OX=9606 GN=LMAN1 PE=1 SV=2 5.98 3358.6 - 764017 - - - 0.8825 - 4.313 0.569 - 137.3 1 2 0 0.0026 28 0 0 0 7.92E+07 4.32E+07 - - - 4.6317 0.9785 221125_WJC_METTL3_EV_vs_WT_F07.20987.20987.4 6.91E-07 Nov-96 L.HDDEVTVTEDKINALIK.A sp|P05386|RLA1_HUMAN 1 1938.9898 1.37 106370 20987 4 1938.99473 485.7547 60S acidic ribosomal protein P1 OS=Homo sapiens OX=9606 GN=RPLP1 PE=1 SV=1 4.43 3358.9 - 193033 - - - 2.524 - 2.047 0.566 - 84.5 1 1 1 0.0049 17 0 0 0 1.01E+07 7.37E+06 - - - 4.3998 1 221125_WJC_METTL3_EV_vs_WT_F07.20998.20998.3 9.94E-09 29/92 K.RYDVGAPSSITISLPGTDPQDAER.R sp|Q12893|TM115_HUMAN 1 2544.2456 1.11 106376 20998 3 2544.248236 849.0891 Transmembrane protein 115 OS=Homo sapiens OX=9606 GN=TMEM115 PE=1 SV=1 4.23 3360.5 - 1.47E+06 - - - 1.0321 - 4.269 0.613 - 688.3 1 2 0 0.0026 24 0 0 0 4.47E+07 4.02E+07 - - - 8.7446 1 221125_WJC_METTL3_EV_vs_WT_F07.21000.21000.4 1.71E-08 33/162 K.GPHLVQSDGTVPFWAHAGNAIPSSDQIR.V sp|P49257|LMAN1_HUMAN 1 2956.458 1.9 106378 21000 4 2956.464115 740.1218 Protein ERGIC-53 OS=Homo sapiens OX=9606 GN=LMAN1 PE=1 SV=2 5.98 3360.7 - 2.40E+06 - - - 2.0673 - 4.834 0.616 - 342 1 2 0 0.0061 28 0 0 0 8.25E+07 4.35E+07 - - - 5.0752 0.9918 221125_WJC_METTL3_EV_vs_WT_F07.21001.21001.4 3.12E-10 13/96 L.HDDEVTVTEDK[136.11]INALIK[136.11].A sp|P05386|RLA1_HUMAN 1 1955.0182 1.4 106379 21001 4 1955.021218 489.7618 60S acidic ribosomal protein P1 OS=Homo sapiens OX=9606 GN=RPLP1 PE=1 SV=1 4.43 3360.8 - 233237 - - - 1.5253 - 2.511 0.605 - 124.9 1 1 1 0.003 17 0 0 0 1.01E+07 7.25E+06 - - - 4.8108 1 221125_WJC_METTL3_EV_vs_WT_F07.21003.21003.4 1.72E-06 14/108 R.GLLQDDAHPTLVTYADHSK[136.11].L "sp|Q86U44|MTA70_HUMAN,tr|F5H6D8|F5H6D8_HUMAN,tr|H0YFV6|H0YFV6_HUMAN,tr|B4DTN4|B4DTN4_HUMAN" 4 2088.0367 0.16 106380 21003 4 2088.039221 523.0165 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 5.13 3361 - 352740 - - - 1.1915 - 2.902 0.552 - 175.7 1 2 0 0.0025 19 0 0 0 1.66E+06 1.05E+07 - - - 4.3903 1 221125_WJC_METTL3_EV_vs_WT_F07.21005.21005.3 2.79E-18 23/64 L.HDDEVTVTEDKINALIK.A sp|P05386|RLA1_HUMAN 1 1938.9898 1.47 106381 21005 3 1938.993156 647.3372 60S acidic ribosomal protein P1 OS=Homo sapiens OX=9606 GN=RPLP1 PE=1 SV=1 4.43 3361.3 - 1.63E+06 - - - 1.7122 - 4.555 0.744 - 889.7 1 1 1 0.0033 17 0 0 0 5.30E+07 3.60E+07 - - - 10.6644 1 221125_WJC_METTL3_EV_vs_WT_F07.21009.21009.3 2.38E-11 18/76 K.HAASDVDLEIESLLNQQSTK[136.11].E "sp|Q86U44|MTA70_HUMAN,tr|F5H6D8|F5H6D8_HUMAN,tr|H0YFV6|H0YFV6_HUMAN,tr|B4DTN4|B4DTN4_HUMAN" 4 2205.1005 0.08 106385 21009 3 2205.102786 736.0408 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 4.31 3361.8 - 419455 - - - 1.0566 - 3.933 0.614 - 393 1 2 0 0.0023 20 0 0 0 1.69E+06 2.00E+07 - - - 8.7071 1 221125_WJC_METTL3_EV_vs_WT_F07.21016.21016.3 1.03E-11 18/76 A.TISANGDKEIGNIISDAMKK.V "sp|P10809|CH60_HUMAN,tr|A0A7I2V599|A0A7I2V599_HUMAN,tr|E7EXB4|E7EXB4_HUMAN,tr|A0A7I2YQ71|A0A7I2YQ71_HUMAN,tr|E7ESH4|E7ESH4_HUMAN,tr|A0A7I2V5M1|A0A7I2V5M1_HUMAN,tr|A0A7I2V5K3|A0A7I2V5K3_HUMAN,tr|A0A7I2V369|A0A7I2V369_HUMAN" 8 2104.0834 0.79 106390 21016 3 2104.087481 702.3684 "60 kDa heat shock protein, mitochondrial OS=Homo sapiens OX=9606 GN=HSPD1 PE=1 SV=2" 5.79 3362.7 - 642950 - - - 1.9305 - 3.227 0.671 - 198.3 1 1 1 0.0041 20 0 0 0 1.79E+07 2.28E+07 - - - 8.8621 1 221125_WJC_METTL3_EV_vs_WT_F07.21017.21017.3 8.43E-06 13/108 K.GPHLVQSDGTVPFWAHAGNAIPSSDQIR[166.11].V sp|P49257|LMAN1_HUMAN 1 2966.4663 2.64 106391 21017 3 2966.465234 989.8294 Protein ERGIC-53 OS=Homo sapiens OX=9606 GN=LMAN1 PE=1 SV=2 5.98 3362.8 - 119250 - - - -0.3502 - 3.174 0.539 - 139.7 1 2 0 -0.001 28 0 0 0 3.76E+06 1.43E+06 - - - 7.2062 1 221125_WJC_METTL3_EV_vs_WT_F07.21024.21024.3 1.34E-11 23/92 K.R[166.11]YDVGAPSSITISLPGTDPQDAER[166.11].R sp|Q12893|TM115_HUMAN 1 2564.2622 1.11 106395 21024 3 2564.25794 855.7613 Transmembrane protein 115 OS=Homo sapiens OX=9606 GN=TMEM115 PE=1 SV=1 4.23 3363.7 - 875555 - - - -1.6418 - 3.888 0.646 - 409.8 1 2 0 -0.0042 24 0 0 0 4.48E+07 4.03E+07 - - - 8.8949 0.9847 221125_WJC_METTL3_EV_vs_WT_F07.21027.21027.4 6.56E-07 18/114 A.TISANGDKEIGNIISDAMKK.V "sp|P10809|CH60_HUMAN,tr|A0A7I2V599|A0A7I2V599_HUMAN,tr|E7EXB4|E7EXB4_HUMAN,tr|A0A7I2YQ71|A0A7I2YQ71_HUMAN,tr|E7ESH4|E7ESH4_HUMAN,tr|A0A7I2V5M1|A0A7I2V5M1_HUMAN,tr|A0A7I2V5K3|A0A7I2V5K3_HUMAN,tr|A0A7I2V369|A0A7I2V369_HUMAN" 8 2104.0834 1.23 106397 21027 4 2104.087612 527.0281 "60 kDa heat shock protein, mitochondrial OS=Homo sapiens OX=9606 GN=HSPD1 PE=1 SV=2" 5.79 3364.1 - 2.33E+06 - - - 1.9928 - 2.5 0.558 - 92.5 1 1 1 0.0042 20 0 0 0 5.77E+07 4.68E+07 - - - 4.388 0.9896 221125_WJC_METTL3_EV_vs_WT_F07.21029.21029.3 0.000221 14/76 A.TISANGDK[136.11]EIGNIISDAMK[136.11]K[136.11].V "sp|P10809|CH60_HUMAN,tr|A0A7I2V599|A0A7I2V599_HUMAN,tr|E7EXB4|E7EXB4_HUMAN,tr|A0A7I2YQ71|A0A7I2YQ71_HUMAN,tr|E7ESH4|E7ESH4_HUMAN,tr|A0A7I2V5M1|A0A7I2V5M1_HUMAN,tr|A0A7I2V5K3|A0A7I2V5K3_HUMAN,tr|A0A7I2V369|A0A7I2V369_HUMAN" 8 2128.126 0.79 106398 21029 3 2128.126812 710.3826 "60 kDa heat shock protein, mitochondrial OS=Homo sapiens OX=9606 GN=HSPD1 PE=1 SV=2" 5.79 3364.3 - 561524 - - - 0.3726 - 2.851 0.525 - 97.5 1 1 1 0.0008 20 0 0 0 1.79E+07 2.28E+07 - - - 6.9347 0.9996 221125_WJC_METTL3_EV_vs_WT_F07.21032.21032.4 0.00113 8/102 R.SPSELFAQHIVTIVHHVK.E "sp|Q9Y2W1|TR150_HUMAN,tr|A0A3B3ITZ9|A0A3B3ITZ9_HUMAN" 2 2041.1109 2.7 106401 21032 4 2041.113128 511.285 Thyroid hormone receptor-associated protein 3 OS=Homo sapiens OX=9606 GN=THRAP3 PE=1 SV=2 6.78 3364.6 - 110178 - - - 1.094 - 1.862 0.343 - 43.4 1 2 0 0.0022 18 0 0 0 7.20E+09 2.67E+09 - - - 2.4238 0.9999 221125_WJC_METTL3_EV_vs_WT_F07.21035.21035.4 0.000345 16/204 R.VVQAASATLPTVPQK[136.11]PSQNFQIQAAEPTPTQVYIR[166.11].T sp|Q02086|SP2_HUMAN 1 3796.0278 0.72 106402 21035 4 3796.031553 950.0142 Transcription factor Sp2 OS=Homo sapiens OX=9606 GN=SP2 PE=1 SV=3 8.56 3365 - 404248 - - - 0.9771 - 2.945 0.399 - 66.3 1 2 0 0.0037 35 0 0 0 4.75E+06 6.57E+06 - - - 3.0181 0.9999 221125_WJC_METTL3_EV_vs_WT_F07.21040.21040.4 1.95E-05 15/204 R.VVQAASATLPTVPQKPSQNFQIQAAEPTPTQVYIR.T sp|Q02086|SP2_HUMAN 1 3778.0054 0.72 106405 21040 4 3778.014727 945.5086 Transcription factor Sp2 OS=Homo sapiens OX=9606 GN=SP2 PE=1 SV=3 8.56 3365.8 - 428143 - - - 2.4756 - 3.105 0.534 - 58.9 1 2 0 0.0094 35 0 0 0 4.75E+06 6.57E+06 - - - 4.2072 0.9999 221125_WJC_METTL3_EV_vs_WT_F07.21041.21041.4 4.36E-06 13/216 K.LVSPPASAAASSPSSSPSPQPVSELDLSSEPQQLTAK[136.11].G "tr|Q5TBP9|Q5TBP9_HUMAN,tr|A0A0C4DFV2|A0A0C4DFV2_HUMAN" 2 3654.8356 1.52 106406 21041 4 3654.83682 914.7162 Protein LSM14 homolog B (Fragment) OS=Homo sapiens OX=9606 GN=LSM14B PE=1 SV=1 4.14 3366 - 316809 - - - 0.339 - 3.04 0.429 - 43.5 1 2 0 0.0012 37 0 0 0 5.75E+06 3.79E+06 - - - 3.2856 0.9999 221125_WJC_METTL3_EV_vs_WT_F07.21053.21053.3 7.16E-07 15/84 R.NALTALFTSSGRPPSQPNTQDK.T "sp|Q9ULV3|CIZ1_HUMAN,tr|Q5SYW2|Q5SYW2_HUMAN,tr|F5H2X7|F5H2X7_HUMAN,tr|H0Y5D5|H0Y5D5_HUMAN,tr|A0A0U1RQR2|A0A0U1RQR2_HUMAN,tr|A0A494C0L7|A0A494C0L7_HUMAN,tr|Q9BTG3|Q9BTG3_HUMAN" 7 2329.1662 3.02 106413 21053 3 2329.170594 777.396 Cip1-interacting zinc finger protein OS=Homo sapiens OX=9606 GN=CIZ1 PE=1 SV=2 8.75 3367.6 - 502832 - - - 1.8702 - 3.146 0.414 - 258.7 1 2 0 0.0044 22 0 0 0 3.85E+08 1.27E+08 - - - 5.8718 1 221125_WJC_METTL3_EV_vs_WT_F07.21056.21056.4 2.89E-07 20/186 K.VGGTNLGAPGAFGQSPFSQPPAPPHQNTFPPR[166.11].S sp|Q96I24|FUBP3_HUMAN 1 3237.5984 2.43 106415 21056 4 3237.604948 810.4069 Far upstream element-binding protein 3 OS=Homo sapiens OX=9606 GN=FUBP3 PE=1 SV=2 9.73 3367.9 - 489672 - - - 2.0379 - 3.493 0.509 - 104.1 1 2 0 0.0066 32 0 0 0 4.53E+07 1.86E+07 - - - 4.0322 0.9999 221125_WJC_METTL3_EV_vs_WT_F07.21070.21070.4 9.17E-05 27/186 K.VGGTNLGAPGAFGQSPFSQPPAPPHQNTFPPR.S sp|Q96I24|FUBP3_HUMAN 1 3227.5901 2.44 106424 21070 4 3227.602104 807.9048 Far upstream element-binding protein 3 OS=Homo sapiens OX=9606 GN=FUBP3 PE=1 SV=2 9.73 3369.7 - 1.41E+06 - - - 3.7254 - 4.218 0.565 - 232.3 1 2 0 0.012 32 0 0 0 4.51E+07 1.84E+07 - - - 4.575 1 221125_WJC_METTL3_EV_vs_WT_F07.21072.21072.4 2.54E-06 16/96 R.DLIGHIVEFSQDQHGSR[166.11].F "sp|Q8TB72|PUM2_HUMAN,tr|A0A0C4DG68|A0A0C4DG68_HUMAN" 2 1946.9474 1.38 106425 21072 4 1946.951815 487.7441 Pumilio homolog 2 OS=Homo sapiens OX=9606 GN=PUM2 PE=1 SV=2 5.21 3370 - 335302 - - - 2.2635 - 2.683 0.533 - 120.5 1 2 0 0.0044 17 0 0 0 3.04E+08 2.20E+08 - - - 4.2067 1 221125_WJC_METTL3_EV_vs_WT_F07.21074.21074.3 1.75E-14 18/124 K.AHIANPSGASTEC[160.03]FVTDNADGTYQVEYTPFEK.G "sp|O75369|FLNB_HUMAN,tr|E7EN95|E7EN95_HUMAN,tr|A0A804HK76|A0A804HK76_HUMAN,tr|A0A804HL72|A0A804HL72_HUMAN" 4 3518.5572 1.63 106426 21074 3 3518.564722 1173.8597 Filamin-B OS=Homo sapiens OX=9606 GN=FLNB PE=1 SV=2 4.17 3370.2 - 164054 - - - 2.1253 - 3.973 0.742 - 178.8 1 2 0 0.0075 32 0 0 0 5.16E+06 3.17E+06 - - - 9.9843 1 221125_WJC_METTL3_EV_vs_WT_F07.21078.21078.3 1.87E-09 20/92 K.DIIEHLNTSGAPADTSDPLQQIC[160.03]K.L "sp|P37198|NUP62_HUMAN,tr|M0QXN5|M0QXN5_HUMAN" 2 2622.2595 4.45 106428 21078 3 2622.266289 875.0938 Nuclear pore glycoprotein p62 OS=Homo sapiens OX=9606 GN=NUP62 PE=1 SV=3 4.22 3370.7 - 342661 - - - 2.5714 - 3.634 0.562 - 433.7 1 2 0 0.0067 24 0 0 0 2.18E+07 4.90E+06 - - - 7.8008 1 221125_WJC_METTL3_EV_vs_WT_F07.21079.21079.4 6.52E-11 20/162 K.DR[166.11]PQEADGIDSVIVVDNVPQVGPDR[166.11]LEK[136.11].L "sp|P55884|EIF3B_HUMAN,tr|C9JZG1|C9JZG1_HUMAN" 2 3087.5831 1.28 106429 21079 4 3087.593659 772.9031 Eukaryotic translation initiation factor 3 subunit B OS=Homo sapiens OX=9606 GN=EIF3B PE=1 SV=3 4.09 3370.9 - 366686 - - - 3.4208 - 3.823 0.647 - 158 1 2 1 0.0106 28 0 0 0 2.43E+07 1.90E+07 - - - 5.2709 1 221125_WJC_METTL3_EV_vs_WT_F07.21080.21080.4 2.39E-09 25/96 R.DLIGHIVEFSQDQHGSR.F "sp|Q8TB72|PUM2_HUMAN,tr|A0A0C4DG68|A0A0C4DG68_HUMAN" 2 1936.9391 1.38 106430 21080 4 1936.945185 485.2421 Pumilio homolog 2 OS=Homo sapiens OX=9606 GN=PUM2 PE=1 SV=2 5.21 3371 - 566427 - - - 3.1219 - 4.079 0.622 - 421.8 1 2 0 0.006 17 0 0 0 3.04E+08 2.20E+08 - - - 5.1263 1 221125_WJC_METTL3_EV_vs_WT_F07.21082.21082.3 1.88E-10 27/124 K.VGGTNLGAPGAFGQSPFSQPPAPPHQNTFPPR.S sp|Q96I24|FUBP3_HUMAN 1 3227.5901 2.54 106431 21082 3 3227.601034 1076.8706 Far upstream element-binding protein 3 OS=Homo sapiens OX=9606 GN=FUBP3 PE=1 SV=2 9.73 3371.2 - 769575 - - - 3.3939 - 4.459 0.676 - 429.6 1 2 0 0.011 32 0 0 0 3.42E+07 1.35E+07 - - - 9.513 1 221125_WJC_METTL3_EV_vs_WT_F07.21087.21087.3 2.87E-09 15/144 R.GQPGNAYDGAGQPSAAYLSMSQGAVANANSTPPPYER.T sp|Q96PK6|RBM14_HUMAN 1 3693.6754 2.81 106434 21087 3 3694.674559 1232.2324 RNA-binding protein 14 OS=Homo sapiens OX=9606 GN=RBM14 PE=1 SV=2 4.37 3371.9 - 152898 - - - 270.5048 - 3.087 0.685 - 69.5 1 2 0 0.9992 37 0 0 0 1.33E+08 4.73E+07 - - - 8.4936 1 221125_WJC_METTL3_EV_vs_WT_F07.21093.21093.4 1.66E-11 24/162 K.DRPQEADGIDSVIVVDNVPQVGPDRLEK.L "sp|P55884|EIF3B_HUMAN,tr|C9JZG1|C9JZG1_HUMAN" 2 3059.5524 1.28 106438 21093 4 3059.5615 765.8954 Eukaryotic translation initiation factor 3 subunit B OS=Homo sapiens OX=9606 GN=EIF3B PE=1 SV=3 4.09 3372.7 - 853224 - - - 2.9883 - 4.86 0.657 - 320.9 1 2 1 0.0091 28 0 0 0 2.43E+07 1.90E+07 - - - 5.4329 1 221125_WJC_METTL3_EV_vs_WT_F07.21094.21094.3 6.56E-10 31/64 R.DLIGHIVEFSQDQHGSR.F "sp|Q8TB72|PUM2_HUMAN,tr|A0A0C4DG68|A0A0C4DG68_HUMAN" 2 1936.9391 1.4 106439 21094 3 1936.943512 646.6537 Pumilio homolog 2 OS=Homo sapiens OX=9606 GN=PUM2 PE=1 SV=2 5.21 3372.8 - 4.64E+06 - - - 2.2582 - 5.416 0.702 - 1763.4 1 2 0 0.0044 17 0 0 0 8.60E+08 6.13E+08 - - - 10.6332 1 221125_WJC_METTL3_EV_vs_WT_F07.21095.21095.3 1.01E-08 19/64 K.EKPKPTPDYLMQLMNDK.K sp|Q96PU8|QKI_HUMAN 1 2047.0118 2.31 106440 21095 3 2047.016075 683.3446 Protein quaking OS=Homo sapiens OX=9606 GN=QKI PE=1 SV=1 6.22 3372.9 - 552748 - - - 2.0718 - 3.41 0.468 - 508.5 1 2 0 0.0042 17 0 0 0 1.01E+08 4.38E+07 - - - 6.8556 1 221125_WJC_METTL3_EV_vs_WT_F07.21096.21096.3 3.58E-08 18/88 R.SPTEQEEPDPANLEVDHDFFQDK.V sp|Q96CU9|FXRD1_HUMAN 1 2686.1671 2.25 106441 21096 3 2686.171334 896.3963 FAD-dependent oxidoreductase domain-containing protein 1 OS=Homo sapiens OX=9606 GN=FOXRED1 PE=1 SV=2 3.84 3373 - 422596 - - - 1.5818 - 4.002 0.653 - 300.3 1 2 0 0.0042 23 0 0 0 1.25E+07 5.57E+06 - - - 9.0725 0.9995 221125_WJC_METTL3_EV_vs_WT_F07.21097.21097.4 0.00178 13/96 K.EK[136.11]PK[136.11]PTPDYLMQLMNDK[136.11].K sp|Q96PU8|QKI_HUMAN 1 2071.0544 2.24 106442 21097 4 2071.057841 518.7709 Protein quaking OS=Homo sapiens OX=9606 GN=QKI PE=1 SV=1 6.22 3373.1 - 403517 - - - 1.6451 - 2.028 0.348 - 80.8 1 2 0 0.0034 17 0 0 0 8.56E+07 3.82E+07 - - - 2.4995 0.9999 221125_WJC_METTL3_EV_vs_WT_F07.21098.21098.3 3.48E-07 Dec-64 K.EK[136.11]PK[136.11]PTPDYLMQLMNDK[136.11].K sp|Q96PU8|QKI_HUMAN 1 2071.0544 2.35 106443 21098 3 2071.058919 691.3588 Protein quaking OS=Homo sapiens OX=9606 GN=QKI PE=1 SV=1 6.22 3373.3 - 316347 - - - 2.1656 - 2.674 0.494 - 174.2 1 2 0 0.0045 17 0 0 0 9.74E+07 4.14E+07 - - - 6.5312 1 221125_WJC_METTL3_EV_vs_WT_F07.21105.21105.3 4.15E-19 27/92 K.SQGLSQLYHNQSQGLLSQLQGQSK.D "sp|P78344|IF4G2_HUMAN,tr|D3DQV9|D3DQV9_HUMAN" 2 2628.3256 2.05 106448 21105 3 2628.332568 877.1158 Eukaryotic translation initiation factor 4 gamma 2 OS=Homo sapiens OX=9606 GN=EIF4G2 PE=1 SV=1 8.33 3374.1 - 1.20E+06 - - - 2.6542 - 5.009 0.699 - 664.3 1 2 0 0.007 24 0 0 0 9.99E+07 4.87E+07 - - - 10.0735 0.9999 221125_WJC_METTL3_EV_vs_WT_F07.21110.21110.4 0.000618 12/156 R.VSGAAPPRPGSSFAHFGFDEQLMHQIR.K "sp|Q86XP3|DDX42_HUMAN,tr|A0A0A0MSJ0|A0A0A0MSJ0_HUMAN" 2 2938.4297 0.35 106451 21110 4 2938.426959 735.6147 ATP-dependent RNA helicase DDX42 OS=Homo sapiens OX=9606 GN=DDX42 PE=1 SV=1 6.9 3374.8 - 315780 - - - -0.926 - 2.525 0.469 - 75.6 1 2 0 -0.0027 27 0 0 0 2.43E+06 6.96E+06 - - - 3.5972 0.9988 221125_WJC_METTL3_EV_vs_WT_F07.21112.21112.4 0.00145 11/102 R.NPVWYQALTHGLNEEQRK.Q sp|O95373|IPO7_HUMAN 1 2182.0919 1.9 106453 21112 4 2182.099956 546.5303 Importin-7 OS=Homo sapiens OX=9606 GN=IPO7 PE=1 SV=1 6.76 3375 - 238109 - - - 3.669 - 2.287 0.37 - 81.6 1 2 0 0.008 18 0 0 0 4.73E+06 2.50E+06 - - - 2.7276 0.9995 221125_WJC_METTL3_EV_vs_WT_F07.21116.21116.4 0.00205 14/102 R.SPSELFAQHIVTIVHHVK[136.11].E "sp|Q9Y2W1|TR150_HUMAN,tr|A0A3B3ITZ9|A0A3B3ITZ9_HUMAN" 2 2049.1251 2.69 106455 21116 4 2049.123341 513.2886 Thyroid hormone receptor-associated protein 3 OS=Homo sapiens OX=9606 GN=THRAP3 PE=1 SV=2 6.78 3375.6 - 1.65E+06 - - - -0.856 - 1.933 0.338 - 97.5 1 2 0 -0.0018 18 0 0 0 6.59E+09 2.45E+09 - - - 2.3932 1 221125_WJC_METTL3_EV_vs_WT_F07.21117.21117.2 5.60E-11 14/32 R.DLIGHIVEFSQDQHGSR[166.11].F "sp|Q8TB72|PUM2_HUMAN,tr|A0A0C4DG68|A0A0C4DG68_HUMAN" 2 1946.9474 1.22 106456 21117 2 1946.945549 974.481 Pumilio homolog 2 OS=Homo sapiens OX=9606 GN=PUM2 PE=1 SV=2 5.21 3375.7 - 245361 - - - -0.9548 - 3.021 0.659 - 548 1 2 0 -0.0019 17 0 0 0 1.20E+07 9.88E+06 - - - 6.6259 1 221125_WJC_METTL3_EV_vs_WT_F07.21121.21121.4 1.25E-09 19/180 K.IEIHEQEAILHNFSSTNPTQVNGSVIDEPVR.L sp|P46013|KI67_HUMAN 1 3472.7223 1.71 106458 21121 4 3472.731134 869.1878 Proliferation marker protein Ki-67 OS=Homo sapiens OX=9606 GN=MKI67 PE=1 SV=2 4.56 3376.2 - 891598 - - - 2.5507 - 3.866 0.624 - 175.5 1 2 0 0.0089 31 0 0 0 1.30E+07 7.63E+06 - - - 5.0658 1 221125_WJC_METTL3_EV_vs_WT_F07.21126.21126.3 5.58E-11 25/64 R.DLIGHIVEFSQDQHGSR[166.11].F "sp|Q8TB72|PUM2_HUMAN,tr|A0A0C4DG68|A0A0C4DG68_HUMAN" 2 1946.9474 1.4 106461 21126 3 1946.946039 649.9897 Pumilio homolog 2 OS=Homo sapiens OX=9606 GN=PUM2 PE=1 SV=2 5.21 3376.9 - 2.45E+07 - - - -0.7032 - 4.625 0.692 - 985.9 1 2 0 -0.0014 17 0 0 0 8.59E+08 6.12E+08 - - - 10.1237 1 221125_WJC_METTL3_EV_vs_WT_F07.21127.21127.3 7.31E-11 21/84 R.NALTALFTSSGR[166.11]PPSQPNTQDK[136.11].T "sp|Q9ULV3|CIZ1_HUMAN,tr|Q5SYW2|Q5SYW2_HUMAN,tr|F5H2X7|F5H2X7_HUMAN,tr|H0Y5D5|H0Y5D5_HUMAN,tr|A0A0U1RQR2|A0A0U1RQR2_HUMAN,tr|A0A494C0L7|A0A494C0L7_HUMAN,tr|Q9BTG3|Q9BTG3_HUMAN" 7 2347.1887 3.02 106462 21127 3 2347.18758 783.4035 Cip1-interacting zinc finger protein OS=Homo sapiens OX=9606 GN=CIZ1 PE=1 SV=2 8.75 3377 - 1.33E+06 - - - -0.4806 - 4.412 0.61 - 605 1 2 0 -0.0011 22 0 0 0 3.84E+08 1.27E+08 - - - 8.8597 1 221125_WJC_METTL3_EV_vs_WT_F07.21129.21129.4 1.49E-10 19/96 R.HATALEELSEQLEQAK[136.11]R[166.11].F sp|P35580|MYH10_HUMAN 1 1970.0188 0.88 106464 21129 4 1970.015082 493.512 Myosin-10 OS=Homo sapiens OX=9606 GN=MYH10 PE=1 SV=3 4.91 3377.2 - 777700 - - - -1.8817 - 3.864 0.616 - 477.8 1 2 0 -0.0037 17 0 0 0 5.03E+07 5.74E+07 - - - 5.0559 0.9999 221125_WJC_METTL3_EV_vs_WT_F07.21130.21130.4 0.000261 15/126 R.NALTALFTSSGRPPSQPNTQDK.T "sp|Q9ULV3|CIZ1_HUMAN,tr|Q5SYW2|Q5SYW2_HUMAN,tr|F5H2X7|F5H2X7_HUMAN,tr|H0Y5D5|H0Y5D5_HUMAN,tr|A0A0U1RQR2|A0A0U1RQR2_HUMAN,tr|A0A494C0L7|A0A494C0L7_HUMAN,tr|Q9BTG3|Q9BTG3_HUMAN" 7 2329.1662 4.38 106465 21130 4 2329.163231 583.2988 Cip1-interacting zinc finger protein OS=Homo sapiens OX=9606 GN=CIZ1 PE=1 SV=2 8.75 3377.3 - 492200 - - - -1.291 - 3.379 0.405 - 145 1 2 0 -0.003 22 0 0 0 4.57E+07 1.04E+07 - - - 3.1487 1 221125_WJC_METTL3_EV_vs_WT_F07.21134.21134.2 3.74E-10 16/32 R.DLIGHIVEFSQDQHGSR.F "sp|Q8TB72|PUM2_HUMAN,tr|A0A0C4DG68|A0A0C4DG68_HUMAN" 2 1936.9391 1.22 106467 21134 2 1936.940103 969.4768 Pumilio homolog 2 OS=Homo sapiens OX=9606 GN=PUM2 PE=1 SV=2 5.21 3377.8 - 542216 - - - 0.4982 - 3.261 0.693 - 737.6 1 2 0 0.001 17 0 0 0 1.20E+07 9.88E+06 - - - 7.0653 1 221125_WJC_METTL3_EV_vs_WT_F07.21135.21135.3 1.14E-13 25/56 L.IGHIVEFSQDQHGSR.F "sp|Q8TB72|PUM2_HUMAN,tr|A0A0C4DG68|A0A0C4DG68_HUMAN" 2 1708.8281 1.4 106468 21135 3 1708.823322 570.6167 Pumilio homolog 2 OS=Homo sapiens OX=9606 GN=PUM2 PE=1 SV=2 5.99 3378 - 764686 - - - -2.8142 - 3.813 0.687 - 1097.6 1 1 0 -0.0048 15 0 0 0 1.99E+07 1.42E+07 - - - 9.6905 1 221125_WJC_METTL3_EV_vs_WT_F07.21144.21144.3 2.50E-11 23/56 L.IGHIVEFSQDQHGSR[166.11].F "sp|Q8TB72|PUM2_HUMAN,tr|A0A0C4DG68|A0A0C4DG68_HUMAN" 2 1718.8364 1.4 106473 21144 3 1718.832513 573.9527 Pumilio homolog 2 OS=Homo sapiens OX=9606 GN=PUM2 PE=1 SV=2 5.99 3379.1 - 668514 - - - -2.262 - 3.885 0.655 - 820.6 1 1 0 -0.0039 15 0 0 0 1.99E+07 1.42E+07 - - - 9.3828 1 221125_WJC_METTL3_EV_vs_WT_F07.21145.21145.3 2.66E-14 26/64 R.HATALEELSEQLEQAK[136.11]R[166.11].F sp|P35580|MYH10_HUMAN 1 1970.0188 0.84 106474 21145 3 1970.01355 657.6802 Myosin-10 OS=Homo sapiens OX=9606 GN=MYH10 PE=1 SV=3 4.91 3379.2 - 2.72E+06 - - - -2.6594 - 5.259 0.668 - 1302.4 1 2 0 -0.0052 17 0 0 0 9.76E+07 1.16E+08 - - - 10.1796 1 221125_WJC_METTL3_EV_vs_WT_F07.21156.21156.3 2.76E-09 19/68 R.DVQIGDIVTVGEC[160.03]RPLSK.T "sp|P62280|RS11_HUMAN,tr|M0R1H5|M0R1H5_HUMAN" 2 1985.0252 1.11 106480 21156 3 1985.023357 662.6823 40S ribosomal protein S11 OS=Homo sapiens OX=9606 GN=RPS11 PE=1 SV=3 4.56 3380.6 - 300960 - - - -0.9164 - 3.501 0.605 - 345 1 2 0 -0.0018 18 0 0 0 1.31E+07 1.19E+07 - - - 8.4049 1 221125_WJC_METTL3_EV_vs_WT_F07.21162.21162.3 0.000129 18/68 R.DVQIGDIVTVGEC[160.03]R[166.11]PLSK[136.11].T "sp|P62280|RS11_HUMAN,tr|M0R1H5|M0R1H5_HUMAN" 2 2003.0476 1.11 106483 21162 3 2003.045927 668.6898 40S ribosomal protein S11 OS=Homo sapiens OX=9606 GN=RPS11 PE=1 SV=3 4.56 3381.3 - 639906 - - - -0.8582 - 3.373 0.487 - 328.7 1 2 0 -0.0017 18 0 0 0 1.31E+07 1.19E+07 - - - 6.9966 1 221125_WJC_METTL3_EV_vs_WT_F07.21169.21169.3 4.29E-08 16/100 R.AEETSSPVIGELWSPDQTAEASHVSR[166.11].Y sp|Q86XL3|ANKL2_HUMAN 1 2792.3129 1.82 106487 21169 3 2792.312814 931.7782 Ankyrin repeat and LEM domain-containing protein 2 OS=Homo sapiens OX=9606 GN=ANKLE2 PE=1 SV=4 4.25 3382.2 - 328856 - - - -0.0136 - 3.15 0.64 - 209.4 1 2 0 0 26 0 0 0 2.86E+07 1.57E+07 - - - 8.3151 0.9947 221125_WJC_METTL3_EV_vs_WT_F07.21172.21172.3 4.62E-06 Dec-44 F.AQHIVTIVHHVK.E "sp|Q9Y2W1|TR150_HUMAN,tr|A0A3B3ITZ9|A0A3B3ITZ9_HUMAN" 2 1380.799 2.65 106490 21172 3 1380.796788 461.2736 Thyroid hormone receptor-associated protein 3 OS=Homo sapiens OX=9606 GN=THRAP3 PE=1 SV=2 8.81 3382.6 - 276937 - - - -1.6041 - 2.177 0.499 - 164.3 1 1 0 -0.0022 12 0 0 0 1.93E+08 7.27E+07 - - - 6.2591 1 221125_WJC_METTL3_EV_vs_WT_F07.21176.21176.3 7.53E-09 21/68 R.SPSELFAQHIVTIVHHVK.E "sp|Q9Y2W1|TR150_HUMAN,tr|A0A3B3ITZ9|A0A3B3ITZ9_HUMAN" 2 2041.1109 2.52 106492 21176 3 2041.111233 681.3776 Thyroid hormone receptor-associated protein 3 OS=Homo sapiens OX=9606 GN=THRAP3 PE=1 SV=2 6.78 3383.1 - 2.32E+06 - - - 0.1656 - 4.218 0.628 - 565.6 1 2 0 0.0003 18 0 0 0 2.48E+09 9.84E+08 - - - 9.1256 1 221125_WJC_METTL3_EV_vs_WT_F07.21187.21187.4 8.50E-10 23/96 R.HATALEELSEQLEQAKR.F sp|P35580|MYH10_HUMAN 1 1951.9963 0.87 106499 21187 4 1951.998676 489.0064 Myosin-10 OS=Homo sapiens OX=9606 GN=MYH10 PE=1 SV=3 4.91 3384.6 - 1.59E+06 - - - 1.2075 - 4.279 0.626 - 726.5 1 2 0 0.0024 17 0 0 0 5.00E+07 5.73E+07 - - - 5.1788 0.9984 221125_WJC_METTL3_EV_vs_WT_F07.21188.21188.3 1.44E-06 12/112 P.VAPAPAAPTPAAPAPAPSWPLSSSVPSQK.T "sp|P04637|P53_HUMAN,tr|J3KP33|J3KP33_HUMAN,tr|S4R334|S4R334_HUMAN,tr|A0A0U1RQC9|A0A0U1RQC9_HUMAN,tr|E7EQX7|E7EQX7_HUMAN,tr|E9PCY9|E9PCY9_HUMAN,tr|E7EMR6|E7EMR6_HUMAN" 7 2749.4439 2.58 106500 21188 3 2749.445426 917.4886 Cellular tumor antigen p53 OS=Homo sapiens OX=9606 GN=TP53 PE=1 SV=4 8.72 3384.7 - 170969 - - - 0.5492 - 2.642 0.598 - 72.8 1 1 0 0.0015 29 0 0 0 1.81E+06 7.01E+05 - - - 7.4418 0.9948 221125_WJC_METTL3_EV_vs_WT_F07.21190.21190.3 5.06E-05 Oct-44 F.AQHIVTIVHHVK[136.11].E "sp|Q9Y2W1|TR150_HUMAN,tr|A0A3B3ITZ9|A0A3B3ITZ9_HUMAN" 2 1388.8132 2.65 106502 21190 3 1388.814986 463.945 Thyroid hormone receptor-associated protein 3 OS=Homo sapiens OX=9606 GN=THRAP3 PE=1 SV=2 8.81 3385 - 130677 - - - 1.2838 - 2.165 0.493 - 121.9 1 1 0 0.0018 12 0 0 0 1.93E+08 7.27E+07 - - - 6.177 1 221125_WJC_METTL3_EV_vs_WT_F07.21197.21197.3 5.89E-08 Dec-84 R.SNELGDVGVHC[160.03]VLQGLQTPSC[160.03]K.L "sp|P13489|RINI_HUMAN,tr|E9PLZ3|E9PLZ3_HUMAN,tr|E9PMJ3|E9PMJ3_HUMAN,tr|E9PIK5|E9PIK5_HUMAN,tr|E9PIM9|E9PIM9_HUMAN,tr|E9PMN0|E9PMN0_HUMAN" 6 2397.1417 1.16 106504 21197 3 2397.142376 800.0545 Ribonuclease inhibitor OS=Homo sapiens OX=9606 GN=RNH1 PE=1 SV=2 5.3 3386.1 - 345182 - - - 0.2903 - 2.625 0.6 - 130.7 1 2 0 0.0007 22 0 0 0 5.45E+07 4.70E+07 - - - 7.5173 1 221125_WJC_METTL3_EV_vs_WT_F07.21205.21205.3 3.43E-12 18/84 R.SNELGDVGVHC[160.03]VLQGLQTPSC[160.03]K[136.11].L "sp|P13489|RINI_HUMAN,tr|E9PLZ3|E9PLZ3_HUMAN,tr|E9PMJ3|E9PMJ3_HUMAN,tr|E9PIK5|E9PIK5_HUMAN,tr|E9PIM9|E9PIM9_HUMAN,tr|E9PMN0|E9PMN0_HUMAN" 6 2405.1559 1.16 106508 21205 3 2405.156057 802.7259 Ribonuclease inhibitor OS=Homo sapiens OX=9606 GN=RNH1 PE=1 SV=2 5.3 3387.1 - 402506 - - - 0.0736 - 3.75 0.628 - 318.4 1 2 0 0.0002 22 0 0 0 5.45E+07 4.70E+07 - - - 8.6752 0.9888 221125_WJC_METTL3_EV_vs_WT_F07.21211.21211.4 0.00802 10/120 K.R[166.11]GFAFVTFDDHDSVDK[136.11]IVIQK[136.11].Y "sp|Q32P51|RA1L2_HUMAN,sp|P09651|ROA1_HUMAN,tr|A0A7I2YQX9|A0A7I2YQX9_HUMAN,tr|F8VZ49|F8VZ49_HUMAN,tr|A0A7I2V3R8|A0A7I2V3R8_HUMAN,tr|F8VTQ5|F8VTQ5_HUMAN,tr|F8W6I7|F8W6I7_HUMAN,tr|H0YH80|H0YH80_HUMAN,tr|A0A7I2V2L6|A0A7I2V2L6_HUMAN,tr|A0A7I2V3W0|A0A7I2V3W0_HUMAN,tr|A0A2R8Y4L2|A0A2R8Y4L2_HUMAN" 11 2462.2804 1.16 106511 21211 4 2462.285031 616.5774 Heterogeneous nuclear ribonucleoprotein A1-like 2 OS=Homo sapiens OX=9606 GN=HNRNPA1L2 PE=2 SV=2 5.36 3387.9 - 396988 - - - 1.8686 - 2.052 0.266 - 50.2 1 2 1 0.0046 21 0 0 0 1.84E+07 1.58E+07 - - - 1.7777 0.9998 221125_WJC_METTL3_EV_vs_WT_F07.21212.21212.4 9.00E-14 20/150 K.YQC[160.03]LAC[160.03]DVAISGNEALSQHLQSSLHK.E "sp|Q86UP3|ZFHX4_HUMAN,tr|E7EVZ1|E7EVZ1_HUMAN" 2 2928.3858 1.08 106512 21212 4 2928.372147 733.1037 Zinc finger homeobox protein 4 OS=Homo sapiens OX=9606 GN=ZFHX4 PE=1 SV=1 5.99 3388 - 543739 - - - -4.6712 - 4.653 0.555 - 248.7 1 2 0 -0.0137 26 0 0 0 8.66E+06 7.99E+06 - - - 4.5379 1 221125_WJC_METTL3_EV_vs_WT_F07.21215.21215.3 1.10E-06 21/124 K.VGGTNLGAPGAFGQSPFSQPPAPPHQNTFPPR[166.11].S sp|Q96I24|FUBP3_HUMAN 1 3237.5984 2.74 106514 21215 3 3237.596095 1080.2067 Far upstream element-binding protein 3 OS=Homo sapiens OX=9606 GN=FUBP3 PE=1 SV=2 9.73 3388.3 - 419496 - - - -0.6965 - 3.804 0.671 - 221.4 1 2 0 -0.0023 32 0 0 0 1.33E+08 4.86E+07 - - - 9.0941 0.9982 221125_WJC_METTL3_EV_vs_WT_F07.21217.21217.4 0.000261 13/120 K.RGFAFVTFDDHDSVDKIVIQK.Y "sp|Q32P51|RA1L2_HUMAN,sp|P09651|ROA1_HUMAN,tr|A0A7I2YQX9|A0A7I2YQX9_HUMAN,tr|F8VZ49|F8VZ49_HUMAN,tr|A0A7I2V3R8|A0A7I2V3R8_HUMAN,tr|F8VTQ5|F8VTQ5_HUMAN,tr|F8W6I7|F8W6I7_HUMAN,tr|H0YH80|H0YH80_HUMAN,tr|A0A7I2V2L6|A0A7I2V2L6_HUMAN,tr|A0A7I2V3W0|A0A7I2V3W0_HUMAN,tr|A0A2R8Y4L2|A0A2R8Y4L2_HUMAN" 11 2436.2438 1.16 106515 21217 4 2436.25013 610.0682 Heterogeneous nuclear ribonucleoprotein A1-like 2 OS=Homo sapiens OX=9606 GN=HNRNPA1L2 PE=2 SV=2 5.36 3388.6 - 364979 - - - 2.6147 - 2.236 0.385 - 79.8 1 2 1 0.0064 21 0 0 0 1.83E+07 1.57E+07 - - - 2.8413 0.9998 221125_WJC_METTL3_EV_vs_WT_F07.21219.21219.3 0.00291 9/108 R.KVVGSMPTAGSAGSVPENLNLFPEPGSK.S "sp|Q8WU79|SMAP2_HUMAN,tr|A0A087WV97|A0A087WV97_HUMAN" 2 2769.4007 1.85 106516 21219 3 2769.398823 924.1409 Stromal membrane-associated protein 2 OS=Homo sapiens OX=9606 GN=SMAP2 PE=1 SV=1 6.14 3388.8 - 350831 - - - -0.689 - 1.948 0.408 - 47.8 1 2 0 -0.0019 28 0 0 0 8.90E+07 4.81E+07 - - - 4.6223 1 221125_WJC_METTL3_EV_vs_WT_F07.21221.21221.3 1.03E-08 15/72 R.MDSFDEDLARPSGLLAQER.K "sp|Q9Y2W1|TR150_HUMAN,tr|A0A3B3ITZ9|A0A3B3ITZ9_HUMAN" 2 2149.011 2.86 106517 21221 3 2149.010231 717.3443 Thyroid hormone receptor-associated protein 3 OS=Homo sapiens OX=9606 GN=THRAP3 PE=1 SV=2 4.1 3389 - 1.46E+06 - - - -0.3499 - 2.863 0.588 - 252.1 1 2 0 -0.0008 19 0 0 0 7.80E+07 2.73E+07 - - - 7.6796 1 221125_WJC_METTL3_EV_vs_WT_F07.21223.21223.4 6.14E-10 22/108 R.K[136.11]R[166.11]YDQDLC[160.03]YTDILFTEQER[166.11].G sp|Q15029|U5S1_HUMAN 1 2520.1949 1.57 106519 21223 4 2520.194036 631.056 116 kDa U5 small nuclear ribonucleoprotein component OS=Homo sapiens OX=9606 GN=EFTUD2 PE=1 SV=1 4.44 3389.2 - 833872 - - - -0.3543 - 3.859 0.62 - 409.6 1 2 1 -0.0009 19 0 0 0 4.44E+07 2.83E+07 - - - 5.079 0.9918 221125_WJC_METTL3_EV_vs_WT_F07.21233.21233.4 5.02E-06 15/138 H.SSC[160.03]HIC[160.03]TAADDHQALIWDIQQMPR.A sp|P61962|DCAF7_HUMAN 1 2852.2793 2.97 106524 21233 4 2852.27358 714.0771 DDB1- and CUL4-associated factor 7 OS=Homo sapiens OX=9606 GN=DCAF7 PE=1 SV=1 5.12 3390.6 - 492718 - - - -1.9889 - 2.534 0.478 - 153.6 1 1 0 -0.0057 24 0 0 0 8.70E+06 2.93E+06 - - - 3.6834 1 221125_WJC_METTL3_EV_vs_WT_F07.21237.21237.3 2.14E-11 23/68 R.SPSELFAQHIVTIVHHVK[136.11].E "sp|Q9Y2W1|TR150_HUMAN,tr|A0A3B3ITZ9|A0A3B3ITZ9_HUMAN" 2 2049.1251 2.52 106526 21237 3 2049.123578 684.049 Thyroid hormone receptor-associated protein 3 OS=Homo sapiens OX=9606 GN=THRAP3 PE=1 SV=2 6.78 3391 - 4.60E+06 - - - -0.7403 - 3.984 0.657 - 793.2 1 2 0 -0.0015 18 0 0 0 2.48E+09 9.83E+08 - - - 9.3065 1 221125_WJC_METTL3_EV_vs_WT_F07.21238.21238.4 2.56E-13 26/138 R.HAMNLEAVNTYEGTHDIHALILGR.A sp|Q92947|GCDH_HUMAN 1 2674.3286 1.43 106527 21238 4 2674.331237 669.5894 "Glutaryl-CoA dehydrogenase, mitochondrial OS=Homo sapiens OX=9606 GN=GCDH PE=1 SV=1" 5.75 3391.1 - 2.92E+06 - - - 0.9976 - 4.905 0.702 - 577.5 1 2 0 0.0027 24 0 0 0 8.48E+07 5.93E+07 - - - 5.8459 1 221125_WJC_METTL3_EV_vs_WT_F07.21241.21241.4 3.54E-09 19/132 R.LVRPEVDVMC[160.03]TAFHDNEETFLKK.Y "sp|P02768|ALBU_HUMAN,tr|A0A087WWT3|A0A087WWT3_HUMAN,tr|H7C013|H7C013_HUMAN,tr|A0A0C4DGB6|A0A0C4DGB6_HUMAN" 4 2777.3517 71.61 106528 21241 4 2777.357815 695.3452 Albumin OS=Homo sapiens OX=9606 GN=ALB PE=1 SV=2 4.9 3391.5 - 801218 - - - 2.2118 - 3.759 0.58 - 172.1 1 2 0 0.0061 23 0 0 0 2.45E+07 3.43E+05 - - - 4.7016 1 221125_WJC_METTL3_EV_vs_WT_F07.21255.21255.3 2.57E-13 23/96 K.VFNNIGADLLTGSESENKEDGLQNK.H "sp|Q6P3W7|SCYL2_HUMAN,tr|F8VSC5|F8VSC5_HUMAN,tr|A0A0U1RQQ9|A0A0U1RQQ9_HUMAN" 3 2691.2988 1.45 106534 21255 3 2691.317954 898.1069 SCY1-like protein 2 OS=Homo sapiens OX=9606 GN=SCYL2 PE=1 SV=1 4.18 3393.4 - 1.07E+06 - - - 7.1289 - 4.194 0.633 - 652.5 1 2 1 0.0192 25 0 0 0 1.94E+07 1.34E+07 - - - 8.8903 1 221125_WJC_METTL3_EV_vs_WT_F07.21257.21257.3 2.75E-05 14/68 K.TVTNAVVTVPAYFNDSQR[166.11].Q "sp|P11142|HSP7C_HUMAN,tr|E9PQQ4|E9PQQ4_HUMAN,tr|E9PN89|E9PN89_HUMAN,tr|E9PLF4|E9PLF4_HUMAN,tr|E9PI65|E9PI65_HUMAN,tr|E9PK54|E9PK54_HUMAN,tr|E9PQK7|E9PQK7_HUMAN" 7 1990.9988 0.06 106536 21257 3 1990.99922 664.6735 Heat shock cognate 71 kDa protein OS=Homo sapiens OX=9606 GN=HSPA8 PE=1 SV=1 5.5 3393.7 - 658259 - - - 0.2235 - 2.882 0.494 - 279.9 1 2 0 0.0004 18 0 0 0 3.05E+06 5.32E+07 - - - 6.6832 0.996 221125_WJC_METTL3_EV_vs_WT_F07.21258.21258.4 1.04E-05 15/96 S.PSELFAQHIVTIVHHVK[136.11].E "sp|Q9Y2W1|TR150_HUMAN,tr|A0A3B3ITZ9|A0A3B3ITZ9_HUMAN" 2 1962.0931 2.74 106537 21258 4 1962.092893 491.5305 Thyroid hormone receptor-associated protein 3 OS=Homo sapiens OX=9606 GN=THRAP3 PE=1 SV=2 7.42 3393.8 - 350675 - - - -0.0882 - 2.969 0.5 - 143.9 1 1 0 -0.0002 17 0 0 0 4.59E+07 1.68E+07 - - - 3.9558 0.9916 221125_WJC_METTL3_EV_vs_WT_F07.21265.21265.4 1.37E-06 13/72 L.FAQHIVTIVHHVK.E "sp|Q9Y2W1|TR150_HUMAN,tr|A0A3B3ITZ9|A0A3B3ITZ9_HUMAN" 2 1527.8674 2.83 106542 21265 4 1527.864247 382.9741 Thyroid hormone receptor-associated protein 3 OS=Homo sapiens OX=9606 GN=THRAP3 PE=1 SV=2 8.77 3394.7 - 360506 - - - -2.0748 - 2.028 0.485 - 86.9 1 1 0 -0.0032 13 0 0 0 2.55E+07 8.98E+06 - - - 3.7087 1 221125_WJC_METTL3_EV_vs_WT_F07.21267.21267.4 3.88E-09 18/102 R.SPSELFAQHIVTIVHHVK.E "sp|Q9Y2W1|TR150_HUMAN,tr|A0A3B3ITZ9|A0A3B3ITZ9_HUMAN" 2 2041.1109 2.7 106543 21267 4 2041.11156 511.285 Thyroid hormone receptor-associated protein 3 OS=Homo sapiens OX=9606 GN=THRAP3 PE=1 SV=2 6.78 3394.9 - 9.21E+07 - - - 0.3258 - 3.241 0.571 - 258.8 1 2 0 0.0007 18 0 0 0 7.20E+09 2.67E+09 - - - 4.5986 1 221125_WJC_METTL3_EV_vs_WT_F07.21271.21271.4 1.14E-17 33/138 R.HAMNLEAVNTYEGTHDIHALILGR[166.11].A sp|Q92947|GCDH_HUMAN 1 2684.3368 1.43 106545 21271 4 2684.332856 672.0915 "Glutaryl-CoA dehydrogenase, mitochondrial OS=Homo sapiens OX=9606 GN=GCDH PE=1 SV=1" 5.75 3395.4 - 2.46E+06 - - - -1.4838 - 5.057 0.707 - 714.1 1 2 0 -0.004 24 0 0 0 8.48E+07 5.93E+07 - - - 5.8988 0.9999 221125_WJC_METTL3_EV_vs_WT_F07.21278.21278.3 4.32E-09 18/108 R.K[136.11]VVGSMPTAGSAGSVPENLNLFPEPGSK[136.11].S "sp|Q8WU79|SMAP2_HUMAN,tr|A0A087WV97|A0A087WV97_HUMAN" 2 2785.4291 1.85 106550 21278 3 2785.439454 929.4837 Stromal membrane-associated protein 2 OS=Homo sapiens OX=9606 GN=SMAP2 PE=1 SV=1 6.14 3396.2 - 504337 - - - 3.7061 - 3.515 0.572 - 177.6 1 2 0 0.0103 28 0 0 0 8.90E+07 4.81E+07 - - - 7.8064 1 221125_WJC_METTL3_EV_vs_WT_F07.21279.21279.3 1.09E-09 22/80 R.EEAENTLQSFRQDVDNASLAR.L "sp|P08670|VIME_HUMAN,tr|B0YJC5|B0YJC5_HUMAN,tr|B0YJC4|B0YJC4_HUMAN" 3 2392.1255 3.03 106551 21279 3 2392.126191 798.3824 Vimentin OS=Homo sapiens OX=9606 GN=VIM PE=1 SV=4 4.18 3396.3 - 1.31E+06 - - - 0.291 - 3.807 0.603 - 813.4 1 2 1 0.0007 21 0 0 0 5.08E+07 1.68E+07 - - - 8.4677 0.9998 221125_WJC_METTL3_EV_vs_WT_F07.21281.21281.3 0.000496 16/80 R.EEAENTLQSFR[166.11]QDVDNASLAR[166.11].L "sp|P08670|VIME_HUMAN,tr|B0YJC5|B0YJC5_HUMAN,tr|B0YJC4|B0YJC4_HUMAN" 3 2412.142 2.92 106553 21281 3 2412.138312 805.0546 Vimentin OS=Homo sapiens OX=9606 GN=VIM PE=1 SV=4 4.18 3396.6 - 747805 - - - -1.5434 - 2.931 0.485 - 368.6 1 2 1 -0.0037 21 0 0 0 4.89E+07 1.68E+07 - - - 6.5243 1 221125_WJC_METTL3_EV_vs_WT_F07.21282.21282.3 1.15E-07 14/60 K.K[136.11]DC[160.03]EVVMMIGLPGAGK[136.11].T "sp|Q00839|HNRPU_HUMAN,tr|A0A1W2PQL0|A0A1W2PQL0_HUMAN,tr|A0A1W2PPL4|A0A1W2PPL4_HUMAN,tr|A0A1W2PQ74|A0A1W2PQ74_HUMAN,tr|Q5RI18|Q5RI18_HUMAN,tr|A0A1W2PP35|A0A1W2PP35_HUMAN,tr|A0A1W2PPS1|A0A1W2PPS1_HUMAN,tr|A0A1W2PRZ7|A0A1W2PRZ7_HUMAN,tr|A0A1W2PPH7|A0A1W2PPH7_HUMAN,tr|A0A1W2PQD4|A0A1W2PQD4_HUMAN,tr|A0A1W2PP34|A0A1W2PP34_HUMAN,tr|A0A1X7SBS1|A0A1X7SBS1_HUMAN" 12 1719.8693 0.97 106554 21282 3 1719.870373 574.297 Heterogeneous nuclear ribonucleoprotein U OS=Homo sapiens OX=9606 GN=HNRNPU PE=1 SV=6 6.06 3396.7 - 354464 - - - 0.6413 - 2.591 0.563 - 244.6 1 2 0 0.0011 16 0 0 0 1.32E+07 1.37E+07 - - - 7.2594 1 221125_WJC_METTL3_EV_vs_WT_F07.21291.21291.4 1.21E-09 13/156 K.K[136.11]IEPELDGSAQVTSHDASTNGLINFIK[136.11].Q "sp|P06744|G6PI_HUMAN,tr|K7EQ48|K7EQ48_HUMAN,tr|A0A2U3TZU2|A0A2U3TZU2_HUMAN" 3 2899.4898 0.92 106560 21291 4 2899.491727 725.8797 Glucose-6-phosphate isomerase OS=Homo sapiens OX=9606 GN=GPI PE=1 SV=4 4.75 3397.8 - 490241 - - - 0.6587 - 3.088 0.528 - 78 1 2 0 0.0019 27 0 0 0 2.32E+07 2.51E+07 - - - 4.174 0.9998 221125_WJC_METTL3_EV_vs_WT_F07.21293.21293.3 8.52E-07 15/60 K.KDC[160.03]EVVMMIGLPGAGK.T "sp|Q00839|HNRPU_HUMAN,tr|A0A1W2PQL0|A0A1W2PQL0_HUMAN,tr|A0A1W2PPL4|A0A1W2PPL4_HUMAN,tr|A0A1W2PQ74|A0A1W2PQ74_HUMAN,tr|Q5RI18|Q5RI18_HUMAN,tr|A0A1W2PP35|A0A1W2PP35_HUMAN,tr|A0A1W2PPS1|A0A1W2PPS1_HUMAN,tr|A0A1W2PRZ7|A0A1W2PRZ7_HUMAN,tr|A0A1W2PPH7|A0A1W2PPH7_HUMAN,tr|A0A1W2PQD4|A0A1W2PQD4_HUMAN,tr|A0A1W2PP34|A0A1W2PP34_HUMAN,tr|A0A1X7SBS1|A0A1X7SBS1_HUMAN" 12 1703.8409 0.97 106562 21293 3 1703.848841 568.9542 Heterogeneous nuclear ribonucleoprotein U OS=Homo sapiens OX=9606 GN=HNRNPU PE=1 SV=6 6.06 3398.1 - 314097 - - - 4.6783 - 2.883 0.529 - 253.5 1 2 0 0.008 16 0 0 0 1.33E+07 1.37E+07 - - - 7.1524 0.9998 221125_WJC_METTL3_EV_vs_WT_F07.21298.21298.2 2.22E-06 Dec-34 K.TVTNAVVTVPAYFNDSQR[166.11].Q "sp|P11142|HSP7C_HUMAN,tr|E9PQQ4|E9PQQ4_HUMAN,tr|E9PN89|E9PN89_HUMAN,tr|E9PLF4|E9PLF4_HUMAN,tr|E9PI65|E9PI65_HUMAN,tr|E9PK54|E9PK54_HUMAN,tr|E9PQK7|E9PQK7_HUMAN" 7 1990.9988 0.01 106564 21298 2 1990.994951 996.5067 Heat shock cognate 71 kDa protein OS=Homo sapiens OX=9606 GN=HSPA8 PE=1 SV=1 5.5 3398.8 - 446962 - - - -1.9206 - 2.581 0.523 - 242.9 1 2 0 -0.0038 18 0 0 0 2.00E+05 1.53E+07 - - - 5.2338 0.9984 221125_WJC_METTL3_EV_vs_WT_F07.21299.21299.4 9.57E-12 28/96 S.PSELFAQHIVTIVHHVK.E "sp|Q9Y2W1|TR150_HUMAN,tr|A0A3B3ITZ9|A0A3B3ITZ9_HUMAN" 2 1954.0789 2.22 106565 21299 4 1954.080352 489.527 Thyroid hormone receptor-associated protein 3 OS=Homo sapiens OX=9606 GN=THRAP3 PE=1 SV=2 7.42 3398.9 - 1.02E+06 - - - 0.7605 - 4.164 0.606 - 665.7 1 1 0 0.0015 17 0 0 0 6.35E+07 2.86E+07 - - - 4.9955 1 221125_WJC_METTL3_EV_vs_WT_F07.21300.21300.4 7.83E-06 28/186 K.VGGTNLGAPGAFGQSPFSQPPAPPHQNTFPPR[166.11].S sp|Q96I24|FUBP3_HUMAN 1 3237.5984 2.8 106566 21300 4 3237.600538 810.4069 Far upstream element-binding protein 3 OS=Homo sapiens OX=9606 GN=FUBP3 PE=1 SV=2 9.73 3399 - 760987 - - - 0.6758 - 3.995 0.48 - 314.7 1 2 0 0.0022 32 0 0 0 6.93E+07 2.48E+07 - - - 3.8215 1 221125_WJC_METTL3_EV_vs_WT_F07.21304.21304.4 1.32E-14 30/132 R.HVNIDHLHVGWYQSTYYGSFVTR[166.11].A "sp|O15372|EIF3H_HUMAN,tr|B3KS98|B3KS98_HUMAN,tr|A0A087WZK9|A0A087WZK9_HUMAN,tr|E5RFH0|E5RFH0_HUMAN,tr|E5RGU4|E5RGU4_HUMAN,tr|E5RJT0|E5RJT0_HUMAN" 6 2788.3386 1.99 106568 21304 4 2788.337992 698.0919 Eukaryotic translation initiation factor 3 subunit H OS=Homo sapiens OX=9606 GN=EIF3H PE=1 SV=1 7.02 3399.6 - 1.10E+06 - - - -0.2012 - 4.649 0.674 - 699.1 1 2 0 -0.0006 23 0 0 0 6.65E+07 3.33E+07 - - - 5.5902 0.9999 221125_WJC_METTL3_EV_vs_WT_F07.21306.21306.3 1.37E-07 15/44 R.AR[166.11]FEELC[160.03]SDLFR[166.11].S "sp|P48741|HSP77_HUMAN,sp|P0DMV8|HS71A_HUMAN,sp|P0DMV9|HS71B_HUMAN,sp|P17066|HSP76_HUMAN,tr|V9GZ37|V9GZ37_HUMAN,tr|A0A0G2JIW1|A0A0G2JIW1_HUMAN" 6 1561.7462 0.06 106570 21306 3 1561.744039 521.5893 Putative heat shock 70 kDa protein 7 OS=Homo sapiens OX=9606 GN=HSPA7 PE=5 SV=2 4.68 3399.8 - 597092 - - - -1.3856 - 2.775 0.54 - 421.3 1 2 1 -0.0022 12 0 0 0 1.33E+06 2.26E+07 - - - 7.389 1 221125_WJC_METTL3_EV_vs_WT_F07.21309.21309.4 1.54E-13 32/186 K.VGGTNLGAPGAFGQSPFSQPPAPPHQNTFPPR.S sp|Q96I24|FUBP3_HUMAN 1 3227.5901 2.84 106571 21309 4 3227.588873 807.9048 Far upstream element-binding protein 3 OS=Homo sapiens OX=9606 GN=FUBP3 PE=1 SV=2 9.73 3400.2 - 1.64E+06 - - - -0.374 - 4.961 0.612 - 348.6 1 2 0 -0.0012 32 0 0 0 6.41E+07 2.25E+07 - - - 5.0361 1 221125_WJC_METTL3_EV_vs_WT_F07.21318.21318.3 8.66E-12 27/124 K.VGGTNLGAPGAFGQSPFSQPPAPPHQNTFPPR.S sp|Q96I24|FUBP3_HUMAN 1 3227.5901 3.12 106573 21318 3 3227.60141 1076.8706 Far upstream element-binding protein 3 OS=Homo sapiens OX=9606 GN=FUBP3 PE=1 SV=2 9.73 3401.5 - 1.43E+06 - - - 3.5104 - 4.749 0.645 - 463.1 1 2 0 0.0113 32 0 0 0 5.22E+07 1.67E+07 - - - 9.3122 0.9999 221125_WJC_METTL3_EV_vs_WT_F07.21322.21322.4 5.00E-05 9/168 R.LSIPKPNLNSTGVNMMSSVHLQQNNYGVK.S "sp|Q9H2P0|ADNP_HUMAN,tr|A0A2R8Y6X0|A0A2R8Y6X0_HUMAN,tr|A0A669KBJ7|A0A669KBJ7_HUMAN" 3 3169.6012 0.92 106574 21322 4 3169.606672 793.4076 Activity-dependent neuroprotector homeobox protein OS=Homo sapiens OX=9606 GN=ADNP PE=1 SV=1 9.7 3402.1 - 638295 - - - 1.7144 - 2.236 0.425 - 18.6 1 2 0 0.0054 29 0 0 0 8.18E+06 8.92E+06 - - - 3.1717 1 221125_WJC_METTL3_EV_vs_WT_F07.21327.21327.3 1.11E-10 16/92 R.QR[166.11]PGASTDSSTQGANLPDFELLSR[166.11].L "sp|Q9UPT8|ZC3H4_HUMAN,tr|M0QY97|M0QY97_HUMAN" 2 2566.2526 0.56 106576 21327 3 2566.248057 856.4248 Zinc finger CCCH domain-containing protein 4 OS=Homo sapiens OX=9606 GN=ZC3H4 PE=1 SV=3 4.56 3402.7 - 417952 - - - -1.789 - 3.279 0.62 - 125.1 1 2 0 -0.0046 24 0 0 0 7.10E+06 1.27E+07 - - - 8.2093 0.9913 221125_WJC_METTL3_EV_vs_WT_F07.21330.21330.3 0.000184 Nov-52 E.LFAQHIVTIVHHVK.E "sp|Q9Y2W1|TR150_HUMAN,tr|A0A3B3ITZ9|A0A3B3ITZ9_HUMAN" 2 1640.9515 3.41 106578 21330 3 1640.94917 547.9911 Thyroid hormone receptor-associated protein 3 OS=Homo sapiens OX=9606 GN=THRAP3 PE=1 SV=2 8.77 3403 - 180381 - - - -1.4083 - 2.131 0.451 - 108.5 1 1 0 -0.0023 14 0 0 0 1.06E+07 3.09E+06 - - - 5.5782 0.9946 221125_WJC_METTL3_EV_vs_WT_F07.21331.21331.4 4.67E-07 22/108 K.ISSIQSIVPALEIANAHR[166.11]K[136.11].P "sp|P10809|CH60_HUMAN,tr|A0A7I2V2X6|A0A7I2V2X6_HUMAN,tr|A0A7I2YQK6|A0A7I2YQK6_HUMAN,tr|A0A7I2V599|A0A7I2V599_HUMAN,tr|A0A7I2YQ71|A0A7I2YQ71_HUMAN,tr|A0A7I2V5M1|A0A7I2V5M1_HUMAN,tr|A0A7I2V5K3|A0A7I2V5K3_HUMAN,tr|A0A7I2V369|A0A7I2V369_HUMAN" 8 2064.181 0.001 106579 21331 4 2064.17479 517.0525 "60 kDa heat shock protein, mitochondrial OS=Homo sapiens OX=9606 GN=HSPD1 PE=1 SV=2" 8.75 3403.1 - 369337 - - - -3.0293 - 3.54 0.594 - 400.6 1 1 0 -0.0063 19 0 0 0 0.00E+00 1.07E+07 - - - 4.8221 0.9997 221125_WJC_METTL3_EV_vs_WT_F07.21341.21341.4 1.61E-05 22/162 K.AIGSSPLGSGEGLLGLSPGPNGHSHLLK[136.11].V "sp|Q8IY67|RAVR1_HUMAN,tr|K7EQG2|K7EQG2_HUMAN,tr|E9PAU2|E9PAU2_HUMAN,tr|A0A087WZ13|A0A087WZ13_HUMAN" 4 2659.4173 0.93 106584 21341 4 2659.418365 665.8616 Ribonucleoprotein PTB-binding 1 OS=Homo sapiens OX=9606 GN=RAVER1 PE=1 SV=1 6.96 3404.5 - 766059 - - - 0.3952 - 3.457 0.344 - 215.9 1 2 0 0.0011 28 0 0 0 1.54E+07 1.65E+07 - - - 2.605 0.9998 221125_WJC_METTL3_EV_vs_WT_F07.21344.21344.2 0.00154 16-Oct R.YLDVSILGK[136.11].F sp|Q86U44|MTA70_HUMAN 1 1014.5841 0.02 106585 21344 2 1014.584977 508.2993 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 5.83 3404.9 - 2.91E+06 - - - 0.8664 - 1.934 0.483 - 249.5 1 2 0 0.0009 9 0 0 0 2.93E+06 1.78E+08 - - - 4.5164 0.9999 221125_WJC_METTL3_EV_vs_WT_F07.21347.21347.4 3.78E-06 21/162 K.AIGSSPLGSGEGLLGLSPGPNGHSHLLK.V "sp|Q8IY67|RAVR1_HUMAN,tr|K7EQG2|K7EQG2_HUMAN,tr|E9PAU2|E9PAU2_HUMAN,tr|A0A087WZ13|A0A087WZ13_HUMAN" 4 2651.4031 0.93 106587 21347 4 2651.408763 663.8581 Ribonucleoprotein PTB-binding 1 OS=Homo sapiens OX=9606 GN=RAVER1 PE=1 SV=1 6.96 3405.2 - 687365 - - - 2.1306 - 3.395 0.44 - 166.8 1 2 0 0.0056 28 0 0 0 1.54E+07 1.65E+07 - - - 3.4337 0.9924 221125_WJC_METTL3_EV_vs_WT_F07.21352.21352.4 0.0117 13/120 R.TGSFGDRPARPTLLEQVLNQK.R sp|O00287|RFXAP_HUMAN 1 2326.2393 2.08 106590 21352 4 2326.237688 582.5671 Regulatory factor X-associated protein OS=Homo sapiens OX=9606 GN=RFXAP PE=1 SV=1 8.41 3405.9 - 656657 - - - -0.7114 - 2.533 0.199 - 119 1 2 0 -0.0017 21 0 0 0 3.12E+07 1.50E+07 - - - 1.2649 1 221125_WJC_METTL3_EV_vs_WT_F07.21354.21354.4 2.22E-10 25/102 R.SPSELFAQHIVTIVHHVK[136.11].E "sp|Q9Y2W1|TR150_HUMAN,tr|A0A3B3ITZ9|A0A3B3ITZ9_HUMAN" 2 2049.1251 2.7 106591 21354 4 2049.122724 513.2886 Thyroid hormone receptor-associated protein 3 OS=Homo sapiens OX=9606 GN=THRAP3 PE=1 SV=2 6.78 3406.1 - 2.66E+07 - - - -1.1571 - 4.167 0.628 - 567.8 1 2 0 -0.0024 18 0 0 0 7.19E+09 2.66E+09 - - - 5.1804 0.9999 221125_WJC_METTL3_EV_vs_WT_F07.21362.21362.4 1.48E-09 19/132 R.DK[136.11]LEYFEER[166.11]PFAAASIGQVHLAR[166.11].M sp|Q8NI60|COQ8A_HUMAN 1 2674.3862 1.63 106598 21362 4 2674.385996 669.6038 "Atypical kinase COQ8A, mitochondrial OS=Homo sapiens OX=9606 GN=COQ8A PE=1 SV=1" 5.53 3407.1 - 300630 - - - -0.0669 - 3.299 0.579 - 274.4 1 2 1 -0.0002 23 0 0 0 4.21E+06 2.58E+06 - - - 4.6523 0.9906 221125_WJC_METTL3_EV_vs_WT_F07.21368.21368.4 0.0196 13/120 R.TGSFGDR[166.11]PAR[166.11]PTLLEQVLNQK[136.11].R sp|O00287|RFXAP_HUMAN 1 2354.2701 2.12 106601 21368 4 2354.272129 589.5748 Regulatory factor X-associated protein OS=Homo sapiens OX=9606 GN=RFXAP PE=1 SV=1 8.41 3407.9 - 546914 - - - 0.8691 - 2.18 0.196 - 119.7 1 2 0 0.002 21 0 0 0 3.12E+07 1.47E+07 - - - 1.1891 0.9997 221125_WJC_METTL3_EV_vs_WT_F07.21371.21371.4 2.54E-06 20/150 K.QLPDKWQHDLFDSGFGGGAGVETGGK.L "sp|Q86V81|THOC4_HUMAN,tr|E9PB61|E9PB61_HUMAN" 2 2702.2725 0.84 106602 21371 4 2702.275883 676.5754 THO complex subunit 4 OS=Homo sapiens OX=9606 GN=ALYREF PE=1 SV=3 4.66 3408.3 - 1.59E+06 - - - 1.2541 - 2.964 0.431 - 202 1 2 1 0.0034 26 0 0 0 3.26E+09 3.88E+09 - - - 3.3192 0.9973 221125_WJC_METTL3_EV_vs_WT_F07.21373.21373.4 2.28E-08 29/198 L.NHSLLTTVGWDHQVVHHVVPTEPLPAPGPASVTE.- "sp|Q9BQA1|MEP50_HUMAN,tr|H0Y711|H0Y711_HUMAN" 2 3620.8376 - 106604 21373 4 3620.841967 906.2167 Methylosome protein 50 OS=Homo sapiens OX=9606 GN=WDR77 PE=1 SV=1 5.64 3408.5 - 998105 - - - 1.2113 - 3.803 0.538 - 336.5 1 1 0 0.0044 34 0 0 0 - - - - - 4.3059 1 221125_WJC_METTL3_EV_vs_WT_F07.21379.21379.3 8.99E-12 19/100 K.QLPDKWQHDLFDSGFGGGAGVETGGK.L "sp|Q86V81|THOC4_HUMAN,tr|E9PB61|E9PB61_HUMAN" 2 2702.2725 0.73 106608 21379 3 2702.276368 901.7648 THO complex subunit 4 OS=Homo sapiens OX=9606 GN=ALYREF PE=1 SV=3 4.66 3409.3 - 643626 - - - 1.4336 - 3.819 0.654 - 321.4 1 2 1 0.0039 26 0 0 0 7.01E+08 9.59E+08 - - - 8.9132 0.9896 221125_WJC_METTL3_EV_vs_WT_F07.21382.21382.4 0.00051 13/120 Q.SAFLGNSVLGHLENMHPDNSK.A "sp|Q8IWZ3|ANKH1_HUMAN,tr|A0A0A0MQZ8|A0A0A0MQZ8_HUMAN,tr|H0Y472|H0Y472_HUMAN,tr|H0Y7Y3|H0Y7Y3_HUMAN,tr|H0Y4P6|H0Y4P6_HUMAN,tr|H7C0V5|H7C0V5_HUMAN,tr|H0Y785|H0Y785_HUMAN" 7 2266.0801 1.22 106611 21382 4 2266.0822 567.5273 Ankyrin repeat and KH domain-containing protein 1 OS=Homo sapiens OX=9606 GN=ANKHD1 PE=1 SV=1 5.94 3409.7 - 312656 - - - 0.9422 - 2.656 0.428 - 90.3 1 1 0 0.0021 21 0 0 0 1.63E+07 1.34E+07 - - - 3.2737 0.9988 221125_WJC_METTL3_EV_vs_WT_F07.21387.21387.4 0.000172 19/150 K.QLPDK[136.11]WQHDLFDSGFGGGAGVETGGK[136.11].L "sp|Q86V81|THOC4_HUMAN,tr|E9PB61|E9PB61_HUMAN" 2 2718.3009 0.84 106614 21387 4 2718.304351 680.5825 THO complex subunit 4 OS=Homo sapiens OX=9606 GN=ALYREF PE=1 SV=3 4.66 3410.3 - 2.90E+07 - - - 1.2718 - 2.831 0.352 - 150.9 1 2 1 0.0035 26 0 0 0 3.26E+09 3.88E+09 - - - 2.6171 1 221125_WJC_METTL3_EV_vs_WT_F07.21388.21388.3 1.83E-10 23/100 K.QLPDK[136.11]WQHDLFDSGFGGGAGVETGGK[136.11].L "sp|Q86V81|THOC4_HUMAN,tr|E9PB61|E9PB61_HUMAN" 2 2718.3009 0.73 106615 21388 3 2718.300966 907.1076 THO complex subunit 4 OS=Homo sapiens OX=9606 GN=ALYREF PE=1 SV=3 4.66 3410.4 - 4.31E+06 - - - 0.0265 - 3.872 0.589 - 362.7 1 2 1 0.0001 26 0 0 0 7.00E+08 9.58E+08 - - - 8.2213 0.9969 221125_WJC_METTL3_EV_vs_WT_F07.21390.21390.2 0.00113 16-Jul R.YLDVSILGK.F sp|Q86U44|MTA70_HUMAN 1 1006.5699 0.02 106617 21390 2 1006.572624 504.2922 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 5.83 3410.7 - 165871 - - - 2.7082 - 1.386 0.344 - 108.4 1 2 0 0.0027 9 0 0 0 3.11E+06 1.78E+08 - - - 2.5253 0.9999 221125_WJC_METTL3_EV_vs_WT_F07.21395.21395.3 6.20E-06 26/80 K.NQKDDVAQTDLLQIDPNFGSK.E "sp|P08195|4F2_HUMAN,tr|A0A7P0TAN7|A0A7P0TAN7_HUMAN,tr|J3KPF3|J3KPF3_HUMAN,tr|F5H0E2|F5H0E2_HUMAN,tr|F5H056|F5H056_HUMAN,tr|H0YH36|H0YH36_HUMAN,tr|A0A7P0TAT7|A0A7P0TAT7_HUMAN,tr|F5GZI0|F5GZI0_HUMAN,tr|A0A7P0T8U7|A0A7P0T8U7_HUMAN,tr|A0A7P0T9F7|A0A7P0T9F7_HUMAN,tr|A0A7P0TBF8|A0A7P0TBF8_HUMAN,tr|A0A7P0T8F1|A0A7P0T8F1_HUMAN,tr|A0A7P0Z4A0|A0A7P0Z4A0_HUMAN,tr|F5GZS6|F5GZS6_HUMAN,tr|A0A7P0Z4P5|A0A7P0Z4P5_HUMAN,tr|A0A7P0TAS6|A0A7P0TAS6_HUMAN" 16 2345.1499 1.72 106620 21395 3 2345.154361 782.7239 4F2 cell-surface antigen heavy chain OS=Homo sapiens OX=9606 GN=SLC3A2 PE=1 SV=3 4.14 3411.3 - 1.16E+06 - - - 1.8941 - 4.012 0.541 - 422.5 1 2 1 0.0044 21 0 0 0 4.57E+07 2.65E+07 - - - 7.9011 0.9969 221125_WJC_METTL3_EV_vs_WT_F07.21397.21397.4 2.59E-07 16/120 Q.SAFLGNSVLGHLENMHPDNSK[136.11].A "sp|Q8IWZ3|ANKH1_HUMAN,tr|A0A0A0MQZ8|A0A0A0MQZ8_HUMAN,tr|H0Y472|H0Y472_HUMAN,tr|H0Y7Y3|H0Y7Y3_HUMAN,tr|H0Y4P6|H0Y4P6_HUMAN,tr|H7C0V5|H7C0V5_HUMAN,tr|H0Y785|H0Y785_HUMAN" 7 2274.0943 1.36 106622 21397 4 2274.09355 569.5308 Ankyrin repeat and KH domain-containing protein 1 OS=Homo sapiens OX=9606 GN=ANKHD1 PE=1 SV=1 5.94 3411.6 - 645418 - - - -0.3144 - 3.26 0.523 - 160.1 1 1 0 -0.0007 21 0 0 0 1.62E+07 1.19E+07 - - - 4.1687 0.9959 221125_WJC_METTL3_EV_vs_WT_F07.21398.21398.4 0.0275 12/108 R.GLLQDDAHPTLVTYADHSK[136.11].L "sp|Q86U44|MTA70_HUMAN,tr|F5H6D8|F5H6D8_HUMAN,tr|H0YFV6|H0YFV6_HUMAN,tr|B4DTN4|B4DTN4_HUMAN" 4 2088.0367 0 106623 21398 4 2088.032742 523.0165 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 5.13 3411.7 - 490417 - - - -1.9114 - 1.813 0.251 - 100.2 1 2 0 -0.004 19 0 0 0 4.11E+04 9.79E+06 - - - 1.6109 0.9993 221125_WJC_METTL3_EV_vs_WT_F07.21399.21399.3 1.49E-06 Dec-64 K.KVVDDLLDQITGGDHSR.T "sp|Q9H8M2|BRD9_HUMAN,tr|H0YBR9|H0YBR9_HUMAN,tr|H0YBF1|H0YBF1_HUMAN,tr|H0YAW8|H0YAW8_HUMAN" 4 1866.9436 1.5 106624 21399 3 1866.952637 623.3218 Bromodomain-containing protein 9 OS=Homo sapiens OX=9606 GN=BRD9 PE=1 SV=2 4.56 3411.8 - 315460 - - - 4.8646 - 2.391 0.473 - 173.6 1 2 0 0.0091 17 0 0 0 8.46E+06 5.64E+06 - - - 6.0132 0.9804 221125_WJC_METTL3_EV_vs_WT_F07.21408.21408.2 0.00055 20-Nov F.GGGAGVETGGK[136.11].L "sp|Q86V81|THOC4_HUMAN,tr|E9PB61|E9PB61_HUMAN" 2 896.4443 0.73 106628 21408 2 896.443553 449.2294 THO complex subunit 4 OS=Homo sapiens OX=9606 GN=ALYREF PE=1 SV=3 6 3413 - 456400 - - - -0.8444 - 2.116 0.342 - 522.7 1 1 0 -0.0008 11 0 0 0 3.50E+06 4.80E+06 - - - 3.5944 1 221125_WJC_METTL3_EV_vs_WT_F07.21411.21411.2 2.21E-11 22/50 K.QLPDKWQHDLFDSGFGGGAGVETGGK.L "sp|Q86V81|THOC4_HUMAN,tr|E9PB61|E9PB61_HUMAN" 2 2702.2725 0.7 106629 21411 2 2702.266045 1352.1435 THO complex subunit 4 OS=Homo sapiens OX=9606 GN=ALYREF PE=1 SV=3 4.66 3413.4 - 1.16E+06 - - - -2.3865 - 3.702 0.733 - 842.4 1 2 1 -0.0064 26 0 0 0 1.82E+07 2.62E+07 - - - 7.6708 1 221125_WJC_METTL3_EV_vs_WT_F07.21418.21418.2 1.42E-12 18/50 K.QLPDK[136.11]WQHDLFDSGFGGGAGVETGGK[136.11].L "sp|Q86V81|THOC4_HUMAN,tr|E9PB61|E9PB61_HUMAN" 2 2718.3009 0.7 106633 21418 2 2718.297068 1360.1577 THO complex subunit 4 OS=Homo sapiens OX=9606 GN=ALYREF PE=1 SV=3 4.66 3414.2 - 1.64E+06 - - - -1.4075 - 3.455 0.69 - 478.5 1 2 1 -0.0038 26 0 0 0 1.82E+07 2.62E+07 - - - 7.1843 1 221125_WJC_METTL3_EV_vs_WT_F07.21421.21421.3 1.20E-13 21/92 K.YEHDDIVSTVSVLSSGTQAVSGSK.D "sp|Q9BQA1|MEP50_HUMAN,tr|H0Y711|H0Y711_HUMAN" 2 2465.1922 2.8 106635 21421 3 2465.194212 822.738 Methylosome protein 50 OS=Homo sapiens OX=9606 GN=WDR77 PE=1 SV=1 4.54 3414.6 - 672708 - - - 0.8251 - 4.023 0.654 - 519.3 1 2 0 0.002 24 0 0 0 1.41E+09 5.01E+08 - - - 9.064 1 221125_WJC_METTL3_EV_vs_WT_F07.21431.21431.3 6.98E-16 26/92 K.YEHDDIVSTVSVLSSGTQAVSGSK[136.11].D "sp|Q9BQA1|MEP50_HUMAN,tr|H0Y711|H0Y711_HUMAN" 2 2473.2064 2.8 106638 21431 3 2473.20581 825.4094 Methylosome protein 50 OS=Homo sapiens OX=9606 GN=WDR77 PE=1 SV=1 4.54 3416 - 2.17E+06 - - - -0.2297 - 4.308 0.713 - 848.9 1 2 0 -0.0006 24 0 0 0 1.40E+09 5.01E+08 - - - 9.8812 0.9972 221125_WJC_METTL3_EV_vs_WT_F07.21436.21436.3 1.86E-05 14/44 F.AQHIVTIVHHVK.E "sp|Q9Y2W1|TR150_HUMAN,tr|A0A3B3ITZ9|A0A3B3ITZ9_HUMAN" 2 1380.799 2.65 106641 21436 3 1380.799223 461.2736 Thyroid hormone receptor-associated protein 3 OS=Homo sapiens OX=9606 GN=THRAP3 PE=1 SV=2 8.81 3416.7 - 374528 - - - 0.1593 - 2.47 0.504 - 204.7 1 1 0 0.0002 12 0 0 0 1.91E+08 7.24E+07 - - - 6.6654 1 221125_WJC_METTL3_EV_vs_WT_F07.21438.21438.3 3.07E-10 19/92 K.RESNTPAPSTQGLPDSWGIIAEPR.Q "sp|O14654|IRS4_HUMAN,tr|A0A804CF45|A0A804CF45_HUMAN" 2 2578.2776 2.65 106643 21438 3 2578.271966 860.4331 Insulin receptor substrate 4 OS=Homo sapiens OX=9606 GN=IRS4 PE=1 SV=1 4.68 3416.9 - 583718 - - - -2.177 - 3.779 0.524 - 244.3 1 2 0 -0.0056 24 0 0 0 1.25E+07 4.70E+06 - - - 7.4683 1 221125_WJC_METTL3_EV_vs_WT_F07.21441.21441.3 1.17E-06 21/100 K.SQQSSDPDPNC[160.03]VDRPVEGYLAVAVVR.R "sp|P02788|TRFL_HUMAN,tr|E7EQB2|E7EQB2_HUMAN,tr|E7ER44|E7ER44_HUMAN" 3 2857.3665 41.99 106644 21441 3 2857.364203 953.4628 Lactotransferrin OS=Homo sapiens OX=9606 GN=LTF PE=1 SV=6 4.23 3417.3 - 1.18E+06 - - - -0.7937 - 2.585 0.589 - 257.7 1 2 0 -0.0023 26 0 0 0 6.74E+07 1.61E+06 - - - 7.2911 1 221125_WJC_METTL3_EV_vs_WT_F07.21445.21445.3 8.84E-14 28/108 K.TPTSASSMLELETGLHVTPSPSESSSSR[166.11].A "sp|Q9Y2H2|SAC2_HUMAN,tr|A0A3B3IRJ9|A0A3B3IRJ9_HUMAN,tr|A0A3B3ITL0|A0A3B3ITL0_HUMAN" 3 2884.3636 1.19 106647 21445 3 2884.367159 962.4618 Phosphatidylinositide phosphatase SAC2 OS=Homo sapiens OX=9606 GN=INPP5F PE=1 SV=3 4.75 3417.7 - 552239 - - - 1.2453 - 5.06 0.727 - 629.2 1 2 0 0.0036 28 0 0 0 1.01E+07 8.50E+06 - - - 10.3745 1 221125_WJC_METTL3_EV_vs_WT_F07.21450.21450.4 1.07E-05 23/144 R.SVISHSVTSDMQTIEQESPIMAKPR.K "sp|Q9NP61|ARFG3_HUMAN,tr|H0Y6A0|H0Y6A0_HUMAN" 2 2770.363 1.23 106650 21450 4 2770.3653 693.598 ADP-ribosylation factor GTPase-activating protein 3 OS=Homo sapiens OX=9606 GN=ARFGAP3 PE=1 SV=1 5.42 3418.3 - 3.13E+06 - - - 0.8428 - 4.324 0.606 - 328.2 1 2 0 0.0023 25 0 0 0 9.81E+07 7.96E+07 - - - 4.9658 1 221125_WJC_METTL3_EV_vs_WT_F07.21451.21451.3 2.06E-10 25/88 R.K[136.11]EVEETDEMDQVELVDFDPNQER[166.11].R sp|P31689|DNJA1_HUMAN 1 2811.2512 0.35 106651 21451 3 2811.251469 938.091 DnaJ homolog subfamily A member 1 OS=Homo sapiens OX=9606 GN=DNAJA1 PE=1 SV=2 3.76 3418.5 - 705336 - - - 0.1067 - 4.131 0.729 - 470.7 1 2 0 0.0003 23 0 0 0 1.05E+07 3.00E+07 - - - 9.9953 0.9998 221125_WJC_METTL3_EV_vs_WT_F07.21452.21452.4 0.000131 8/138 K.YEHDDIVSTVSVLSSGTQAVSGSK.D "sp|Q9BQA1|MEP50_HUMAN,tr|H0Y711|H0Y711_HUMAN" 2 2465.1922 2.39 106652 21452 4 2465.196294 617.3053 Methylosome protein 50 OS=Homo sapiens OX=9606 GN=WDR77 PE=1 SV=1 4.54 3418.6 - 483605 - - - 1.6696 - 2.352 0.401 - 41.5 1 2 0 0.0041 24 0 0 0 2.37E+07 9.90E+06 - - - 2.9897 1 221125_WJC_METTL3_EV_vs_WT_F07.21456.21456.3 2.56E-10 13/92 K.R[166.11]ESNTPAPSTQGLPDSWGIIAEPR[166.11].Q "sp|O14654|IRS4_HUMAN,tr|A0A804CF45|A0A804CF45_HUMAN" 2 2598.2941 3.38 106654 21456 3 2598.294265 867.1053 Insulin receptor substrate 4 OS=Homo sapiens OX=9606 GN=IRS4 PE=1 SV=1 4.68 3419.1 - 263595 - - - 0.0562 - 3.152 0.527 - 105.3 1 2 0 0.0001 24 0 0 0 1.59E+07 4.70E+06 - - - 7.0819 0.9999 221125_WJC_METTL3_EV_vs_WT_F07.21457.21457.4 2.24E-05 16/102 R.DK[136.11]TSDLVEEYFEAHSSSK[136.11].V sp|Q13416|ORC2_HUMAN 1 2086.9666 0.93 106655 21457 4 2086.965277 522.7489 Origin recognition complex subunit 2 OS=Homo sapiens OX=9606 GN=ORC2 PE=1 SV=2 4.5 3419.2 - 258230 - - - -0.6315 - 3.414 0.52 - 272.5 1 2 1 -0.0013 18 0 0 0 6.43E+06 6.95E+06 - - - 4.1723 1 221125_WJC_METTL3_EV_vs_WT_F07.21458.21458.3 2.18E-06 19/124 K.VGGTNLGAPGAFGQSPFSQPPAPPHQNTFPPR[166.11].S sp|Q96I24|FUBP3_HUMAN 1 3237.5984 2.86 106656 21458 3 3237.603243 1080.2067 Far upstream element-binding protein 3 OS=Homo sapiens OX=9606 GN=FUBP3 PE=1 SV=2 9.73 3419.4 - 512029 - - - 1.5113 - 3.346 0.584 - 163.2 1 2 0 0.0049 32 0 0 0 4.46E+07 1.56E+07 - - - 7.8283 1 221125_WJC_METTL3_EV_vs_WT_F07.21463.21463.3 1.72E-16 29/96 R.SVISHSVTSDMQTIEQESPIMAK[136.11]PR[166.11].K "sp|Q9NP61|ARFG3_HUMAN,tr|H0Y6A0|H0Y6A0_HUMAN" 2 2788.3854 0.85 106659 21463 3 2788.384467 930.4691 ADP-ribosylation factor GTPase-activating protein 3 OS=Homo sapiens OX=9606 GN=ARFGAP3 PE=1 SV=1 5.42 3420 - 570142 - - - -0.3472 - 4.832 0.756 - 790.9 1 2 0 -0.001 25 0 0 0 1.07E+07 1.27E+07 - - - 10.5925 1 221125_WJC_METTL3_EV_vs_WT_F07.21465.21465.3 1.18E-08 21/88 R.KEVEETDEMDQVELVDFDPNQER.R sp|P31689|DNJA1_HUMAN 1 2793.2287 0.36 106661 21465 3 2793.227975 932.0835 DnaJ homolog subfamily A member 1 OS=Homo sapiens OX=9606 GN=DNAJA1 PE=1 SV=2 3.76 3420.3 - 631646 - - - -0.2592 - 3.793 0.716 - 315.8 1 2 0 -0.0007 23 0 0 0 1.05E+07 2.96E+07 - - - 9.65 1 221125_WJC_METTL3_EV_vs_WT_F07.21471.21471.4 4.83E-16 31/156 K.TKEQASHLGGAVFSGAGNIAAATGLVK.R "sp|Q16143|SYUB_HUMAN,tr|G4Y816|G4Y816_HUMAN" 2 2554.3504 1.52 106665 21471 4 2554.3554 639.5949 Beta-synuclein OS=Homo sapiens OX=9606 GN=SNCB PE=1 SV=1 8.29 3421.1 - 1.88E+06 - - - 1.977 - 5.364 0.62 - 583.6 1 2 1 0.005 27 0 0 0 6.30E+08 4.15E+08 - - - 5.1466 1 221125_WJC_METTL3_EV_vs_WT_F07.21472.21472.3 9.53E-10 17/112 K.FSNSIPQSQTGNSETATPTNVDLPQVIPK.S sp|P46087|NOP2_HUMAN 1 3069.5255 1.14 106666 21472 3 3069.536207 1024.1824 Probable 28S rRNA (cytosine(4447)-C(5))-methyltransferase OS=Homo sapiens OX=9606 GN=NOP2 PE=1 SV=2 4.37 3421.2 - 797059 - - - 3.4966 - 2.636 0.694 - 211.5 1 2 0 0.0107 29 0 0 0 1.52E+07 1.34E+07 - - - 8.5044 1 221125_WJC_METTL3_EV_vs_WT_F07.21477.21477.4 5.75E-15 28/156 K.TK[136.11]EQASHLGGAVFSGAGNIAAATGLVK[136.11].R "sp|Q16143|SYUB_HUMAN,tr|G4Y816|G4Y816_HUMAN" 2 2570.3787 1.52 106669 21477 4 2570.381964 643.602 Beta-synuclein OS=Homo sapiens OX=9606 GN=SNCB PE=1 SV=1 8.29 3421.9 - 2.05E+06 - - - 1.2504 - 5.059 0.637 - 449.5 1 2 1 0.0032 27 0 0 0 6.30E+08 4.15E+08 - - - 5.2768 0.9989 221125_WJC_METTL3_EV_vs_WT_F07.21480.21480.4 3.74E-05 10/138 K.YEHDDIVSTVSVLSSGTQAVSGSK[136.11].D "sp|Q9BQA1|MEP50_HUMAN,tr|H0Y711|H0Y711_HUMAN" 2 2473.2064 2.39 106672 21480 4 2473.216962 619.3089 Methylosome protein 50 OS=Homo sapiens OX=9606 GN=WDR77 PE=1 SV=1 4.54 3422.3 - 504860 - - - 4.2795 - 2.205 0.405 - 58.5 1 2 0 0.0106 24 0 0 0 2.27E+07 9.51E+06 - - - 3.002 1 221125_WJC_METTL3_EV_vs_WT_F07.21486.21486.3 9.69E-20 29/104 K.TKEQASHLGGAVFSGAGNIAAATGLVK.R "sp|Q16143|SYUB_HUMAN,tr|G4Y816|G4Y816_HUMAN" 2 2554.3504 1.54 106676 21486 3 2554.351435 852.4574 Beta-synuclein OS=Homo sapiens OX=9606 GN=SNCB PE=1 SV=1 8.29 3423.1 - 1.71E+06 - - - 0.4248 - 5.64 0.757 - 958.6 1 2 1 0.0011 27 0 0 0 1.97E+08 1.28E+08 - - - 10.9593 1 221125_WJC_METTL3_EV_vs_WT_F07.21487.21487.3 1.45E-15 32/104 K.TK[136.11]EQASHLGGAVFSGAGNIAAATGLVK[136.11].R "sp|Q16143|SYUB_HUMAN,tr|G4Y816|G4Y816_HUMAN" 2 2570.3787 1.54 106677 21487 3 2570.377399 857.8002 Beta-synuclein OS=Homo sapiens OX=9606 GN=SNCB PE=1 SV=1 8.29 3423.2 - 1.29E+06 - - - -0.5256 - 5.485 0.741 - 1093.2 1 2 1 -0.0014 27 0 0 0 1.97E+08 1.28E+08 - - - 10.7168 0.9997 221125_WJC_METTL3_EV_vs_WT_F07.21488.21488.4 0.00306 17/102 R.DKTSDLVEEYFEAHSSSK.V sp|Q13416|ORC2_HUMAN 1 2070.9382 0.93 106678 21488 4 2070.943899 518.7418 Origin recognition complex subunit 2 OS=Homo sapiens OX=9606 GN=ORC2 PE=1 SV=2 4.5 3423.3 - 305896 - - - 2.7543 - 2.763 0.511 - 145.1 1 2 1 0.0057 18 0 0 0 6.43E+06 6.95E+06 - - - 4.0203 0.9999 221125_WJC_METTL3_EV_vs_WT_F07.21491.21491.4 4.76E-07 18/138 K.IETWHK[136.11]PDLGTLENVHGLDPNTWK[136.11].T "sp|P48739|PIPNB_HUMAN,tr|B3KYB7|B3KYB7_HUMAN,tr|A0A0A0MSW4|A0A0A0MSW4_HUMAN,tr|B3KYB6|B3KYB6_HUMAN" 4 2815.4264 1.9 106679 21491 4 2815.435428 704.8639 Phosphatidylinositol transfer protein beta isoform OS=Homo sapiens OX=9606 GN=PITPNB PE=1 SV=2 5.31 3423.7 - 790621 - - - 3.1963 - 3.252 0.483 - 114.5 1 2 0 0.009 24 0 0 0 2.13E+07 1.12E+07 - - - 3.806 1 221125_WJC_METTL3_EV_vs_WT_F07.21493.21493.3 6.13E-08 12/112 K.FSNSIPQSQTGNSETATPTNVDLPQVIPK[136.11].S sp|P46087|NOP2_HUMAN 1 3077.5397 1.32 106680 21493 3 3077.542339 1026.8538 Probable 28S rRNA (cytosine(4447)-C(5))-methyltransferase OS=Homo sapiens OX=9606 GN=NOP2 PE=1 SV=2 4.37 3423.9 - 436953 - - - 0.866 - 2.369 0.619 - 97.9 1 2 0 0.0027 29 0 0 0 2.68E+07 2.03E+07 - - - 7.4247 0.9999 221125_WJC_METTL3_EV_vs_WT_F07.21500.21500.4 3.06E-06 17/138 K.IETWHKPDLGTLENVHGLDPNTWK.T "sp|P48739|PIPNB_HUMAN,tr|B3KYB7|B3KYB7_HUMAN,tr|A0A0A0MSW4|A0A0A0MSW4_HUMAN,tr|B3KYB6|B3KYB6_HUMAN" 4 2799.398 1.99 106684 21500 4 2799.401795 700.8568 Phosphatidylinositol transfer protein beta isoform OS=Homo sapiens OX=9606 GN=PITPNB PE=1 SV=2 5.31 3424.8 - 837822 - - - 1.3453 - 2.725 0.455 - 123.1 1 2 0 0.0038 24 0 0 0 2.24E+07 1.13E+07 - - - 3.507 1 221125_WJC_METTL3_EV_vs_WT_F07.21501.21501.2 6.79E-15 25/36 K.SKELTTEIDNNIEQISSYK.S "sp|P13645|K1C10_HUMAN,tr|A0A1B0GVI3|A0A1B0GVI3_HUMAN" 2 2211.0907 999 106685 21501 2 2211.095506 1106.5526 "Keratin, type I cytoskeletal 10 OS=Homo sapiens OX=9606 GN=KRT10 PE=1 SV=6" 4.41 3424.9 - 1.05E+06 - - - 2.1858 - 4.745 0.679 - 2270.9 1 2 1 0.0048 19 0 0 0 5.89E+08 0.00E+00 - - - 7.8828 0.9997 221125_WJC_METTL3_EV_vs_WT_F07.21502.21502.4 0.0351 13/126 K.GYLTDLNSMIPTHGGDINDIKK.A sp|O94906|PRP6_HUMAN 1 2401.1948 2.97 106686 21502 4 2401.192778 601.306 Pre-mRNA-processing factor 6 OS=Homo sapiens OX=9606 GN=PRPF6 PE=1 SV=1 5.3 3425.1 - 542208 - - - -0.8258 - 2.325 0.365 - 90.3 1 2 0 -0.002 22 0 0 0 2.21E+07 7.43E+06 - - - 2.6785 1 221125_WJC_METTL3_EV_vs_WT_F07.21503.21503.2 8.62E-15 23/46 K.YEHDDIVSTVSVLSSGTQAVSGSK.D "sp|Q9BQA1|MEP50_HUMAN,tr|H0Y711|H0Y711_HUMAN" 2 2465.1922 7.78 106687 21503 2 2465.190109 1233.6034 Methylosome protein 50 OS=Homo sapiens OX=9606 GN=WDR77 PE=1 SV=1 4.54 3425.2 - 383709 - - - -0.8393 - 4.241 0.709 - 1593.3 1 2 0 -0.0021 24 0 0 0 1.18E+07 1.52E+06 - - - 7.8291 1 221125_WJC_METTL3_EV_vs_WT_F07.21505.21505.4 1.19E-09 20/102 R.SPSELFAQHIVTIVHHVK.E "sp|Q9Y2W1|TR150_HUMAN,tr|A0A3B3ITZ9|A0A3B3ITZ9_HUMAN" 2 2041.1109 5.96 106688 21505 4 2041.113051 511.285 Thyroid hormone receptor-associated protein 3 OS=Homo sapiens OX=9606 GN=THRAP3 PE=1 SV=2 6.78 3425.4 - 1.00E+06 - - - 1.0563 - 3.664 0.581 - 334.7 1 2 0 0.0022 18 0 0 0 2.09E+07 3.50E+06 - - - 4.7273 0.9998 221125_WJC_METTL3_EV_vs_WT_F07.21518.21518.4 3.16E-08 16/108 K.SKELTTEIDNNIEQISSYK.S "sp|P13645|K1C10_HUMAN,tr|A0A1B0GVI3|A0A1B0GVI3_HUMAN" 2 2211.0907 26.93 106696 21518 4 2211.088279 553.7799 "Keratin, type I cytoskeletal 10 OS=Homo sapiens OX=9606 GN=KRT10 PE=1 SV=6" 4.41 3426.9 - 849177 - - - -1.0827 - 3.451 0.482 - 210.2 1 2 1 -0.0024 19 0 0 0 3.21E+07 1.19E+06 - - - 3.8397 1 221125_WJC_METTL3_EV_vs_WT_F07.21533.21533.3 6.16E-15 18/104 R.GSSGGGC[160.03]FGGSSGGYGGLGGFGGGSFR.G "sp|P13645|K1C10_HUMAN,tr|A0A1B0GVI3|A0A1B0GVI3_HUMAN" 2 2341.9771 7.11 106702 21533 3 2341.973878 781.6663 "Keratin, type I cytoskeletal 10 OS=Homo sapiens OX=9606 GN=KRT10 PE=1 SV=6" 8.22 3428.9 - 3.86E+06 - - - -1.3574 - 3.503 0.743 - 159.8 1 2 0 -0.0032 27 0 0 0 1.00E+08 1.41E+07 - - - 9.707 0.9999 221125_WJC_METTL3_EV_vs_WT_F07.21534.21534.4 5.52E-13 26/138 R.IGNSGVEEIKGHPFFEGVDWEHIR.E sp|Q9Y2H1|ST38L_HUMAN 1 2751.3405 2.29 106703 21534 4 2751.336432 688.8424 Serine\threonine-protein kinase 38-like OS=Homo sapiens OX=9606 GN=STK38L PE=1 SV=3 4.92 3429 - 824462 - - - -1.4836 - 4.478 0.593 - 406.3 1 2 1 -0.0041 24 0 0 0 3.87E+07 1.69E+07 - - - 4.8675 1 221125_WJC_METTL3_EV_vs_WT_F07.21541.21541.4 5.52E-07 28/186 K.VGGTNLGAPGAFGQSPFSQPPAPPHQNTFPPR[166.11].S sp|Q96I24|FUBP3_HUMAN 1 3237.5984 2.72 106708 21541 4 3237.599096 810.4069 Far upstream element-binding protein 3 OS=Homo sapiens OX=9606 GN=FUBP3 PE=1 SV=2 9.73 3429.9 - 1.12E+06 - - - 0.2304 - 4.233 0.527 - 275 1 2 0 0.0007 32 0 0 0 1.09E+08 4.02E+07 - - - 4.2485 0.9905 221125_WJC_METTL3_EV_vs_WT_F07.21544.21544.3 2.34E-09 19/116 R.GSDIKDLTVC[160.03]EPPKPQC[160.03]SLPQDPAIVQSSL.G "sp|Q8ND56|LS14A_HUMAN,tr|A0A140TA76|A0A140TA76_HUMAN,tr|K7EMZ9|K7EMZ9_HUMAN" 3 3278.6163 0.43 106709 21544 3 3278.61403 1093.8794 Protein LSM14 homolog A OS=Homo sapiens OX=9606 GN=LSM14A PE=1 SV=3 4.23 3430.4 - 1.37E+06 - - - -0.6863 - 3.21 0.525 - 251.8 1 1 1 -0.0022 30 0 0 0 1.59E+07 3.69E+07 - - - 7.0758 1 221125_WJC_METTL3_EV_vs_WT_F07.21548.21548.4 5.88E-08 29/186 K.VGGTNLGAPGAFGQSPFSQPPAPPHQNTFPPR.S sp|Q96I24|FUBP3_HUMAN 1 3227.5901 2.66 106711 21548 4 3227.589601 807.9048 Far upstream element-binding protein 3 OS=Homo sapiens OX=9606 GN=FUBP3 PE=1 SV=2 9.73 3430.8 - 2.73E+06 - - - -0.1484 - 3.834 0.544 - 255.9 1 2 0 -0.0005 32 0 0 0 9.57E+07 3.60E+07 - - - 4.3666 1 221125_WJC_METTL3_EV_vs_WT_F07.21552.21552.3 2.29E-11 25/124 A.GSSLTSFGTETSNSGTLPQSSAVGSAFTQDTR.S "sp|Q8ND56|LS14A_HUMAN,tr|A0A140TA76|A0A140TA76_HUMAN,tr|K7EMZ9|K7EMZ9_HUMAN" 3 3177.4698 1.03 106713 21552 3 3177.466648 1060.1639 Protein LSM14 homolog A OS=Homo sapiens OX=9606 GN=LSM14A PE=1 SV=3 4.37 3431.3 - 1.97E+06 - - - -0.9948 - 4.154 0.642 - 431.3 1 1 0 -0.0032 32 0 0 0 7.06E+07 6.85E+07 - - - 8.9731 1 221125_WJC_METTL3_EV_vs_WT_F07.21556.21556.3 4.08E-07 24/124 A.GSSLTSFGTETSNSGTLPQSSAVGSAFTQDTR[166.11].S "sp|Q8ND56|LS14A_HUMAN,tr|A0A140TA76|A0A140TA76_HUMAN,tr|K7EMZ9|K7EMZ9_HUMAN" 3 3187.4781 1.03 106715 21556 3 3187.473116 1063.5 Protein LSM14 homolog A OS=Homo sapiens OX=9606 GN=LSM14A PE=1 SV=3 4.37 3431.9 - 2.53E+06 - - - -1.557 - 4.018 0.626 - 380.6 1 1 0 -0.005 32 0 0 0 7.06E+07 6.85E+07 - - - 8.7176 1 221125_WJC_METTL3_EV_vs_WT_F07.21558.21558.3 1.15E-07 26/124 K.VGGTNLGAPGAFGQSPFSQPPAPPHQNTFPPR.S sp|Q96I24|FUBP3_HUMAN 1 3227.5901 2.86 106717 21558 3 3227.590722 1076.8706 Far upstream element-binding protein 3 OS=Homo sapiens OX=9606 GN=FUBP3 PE=1 SV=2 9.73 3432.1 - 1.83E+06 - - - 0.1989 - 4.264 0.552 - 390 1 2 0 0.0006 32 0 0 0 7.88E+07 2.75E+07 - - - 8.0305 0.9999 221125_WJC_METTL3_EV_vs_WT_F07.21565.21565.4 6.55E-07 17/120 R.DSFDDRGPSLNPVLDYDHGSR.S "sp|P43243|MATR3_HUMAN,tr|A8MXP9|A8MXP9_HUMAN,tr|D6R991|D6R991_HUMAN,tr|A0A0R4J2E8|A0A0R4J2E8_HUMAN,tr|D6REM6|D6REM6_HUMAN" 5 2361.0622 1.15 106722 21565 4 2361.06014 591.2728 Matrin-3 OS=Homo sapiens OX=9606 GN=MATR3 PE=1 SV=2 4.28 3433 - 719915 - - - -0.8581 - 3.356 0.544 - 170.1 1 2 1 -0.002 21 0 0 0 8.95E+06 7.78E+06 - - - 4.3607 1 221125_WJC_METTL3_EV_vs_WT_F07.21569.21569.4 1.43E-08 23/108 K.K[136.11]ISSIQSIVPALEIANAHR[166.11].K "sp|P10809|CH60_HUMAN,tr|A0A7I2V2X6|A0A7I2V2X6_HUMAN,tr|A0A7I2YQK6|A0A7I2YQK6_HUMAN,tr|A0A7I2V599|A0A7I2V599_HUMAN,tr|A0A7I2YQ71|A0A7I2YQ71_HUMAN,tr|A0A7I2V5M1|A0A7I2V5M1_HUMAN,tr|A0A7I2V5K3|A0A7I2V5K3_HUMAN,tr|A0A7I2V369|A0A7I2V369_HUMAN" 8 2064.181 1.19 106725 21569 4 2064.179876 517.0525 "60 kDa heat shock protein, mitochondrial OS=Homo sapiens OX=9606 GN=HSPD1 PE=1 SV=2" 8.75 3433.5 - 1.18E+06 - - - -0.5654 - 3.952 0.627 - 575.5 1 2 0 -0.0012 19 0 0 0 2.87E+07 2.41E+07 - - - 5.148 0.9998 221125_WJC_METTL3_EV_vs_WT_F07.21572.21572.4 2.84E-05 16/120 R.DSFDDR[166.11]GPSLNPVLDYDHGSR[166.11].S "sp|P43243|MATR3_HUMAN,tr|A8MXP9|A8MXP9_HUMAN,tr|D6R991|D6R991_HUMAN,tr|A0A0R4J2E8|A0A0R4J2E8_HUMAN,tr|D6REM6|D6REM6_HUMAN" 5 2381.0787 1.18 106727 21572 4 2381.079031 596.277 Matrin-3 OS=Homo sapiens OX=9606 GN=MATR3 PE=1 SV=2 4.28 3433.9 - 539025 - - - 0.1365 - 2.688 0.471 - 119.6 1 2 1 0.0003 21 0 0 0 9.39E+06 7.97E+06 - - - 3.6524 1 221125_WJC_METTL3_EV_vs_WT_F07.21575.21575.3 8.38E-07 21/72 K.KISSIQSIVPALEIANAHR.K "sp|P10809|CH60_HUMAN,tr|A0A7I2V2X6|A0A7I2V2X6_HUMAN,tr|A0A7I2YQK6|A0A7I2YQK6_HUMAN,tr|A0A7I2V599|A0A7I2V599_HUMAN,tr|A0A7I2YQ71|A0A7I2YQ71_HUMAN,tr|A0A7I2V5M1|A0A7I2V5M1_HUMAN,tr|A0A7I2V5K3|A0A7I2V5K3_HUMAN,tr|A0A7I2V369|A0A7I2V369_HUMAN" 8 2046.1586 1.2 106730 21575 3 2046.16047 683.0601 "60 kDa heat shock protein, mitochondrial OS=Homo sapiens OX=9606 GN=HSPD1 PE=1 SV=2" 8.75 3434.2 - 829104 - - - 0.9271 - 3.562 0.603 - 519.8 1 2 0 0.0019 19 0 0 0 4.81E+07 4.02E+07 - - - 8.3833 1 221125_WJC_METTL3_EV_vs_WT_F07.21577.21577.4 2.07E-10 21/150 K.EQASHLGGAVFSGAGNIAAATGLVKR.E "sp|Q16143|SYUB_HUMAN,tr|G4Y816|G4Y816_HUMAN" 2 2481.3088 1.52 106732 21577 4 2481.305306 621.3345 Beta-synuclein OS=Homo sapiens OX=9606 GN=SNCB PE=1 SV=1 8.85 3434.5 - 576940 - - - -1.4162 - 4.149 0.597 - 206.2 1 2 0 -0.0035 26 0 0 0 1.28E+07 8.47E+06 - - - 4.8701 1 221125_WJC_METTL3_EV_vs_WT_F07.21578.21578.3 3.27E-11 21/84 K.HSESNAELGQLYWPNTSTLTTR.L sp|Q9P2D1|CHD7_HUMAN 1 2504.1932 0.19 106733 21578 3 2504.192486 835.7383 Chromodomain-helicase-DNA-binding protein 7 OS=Homo sapiens OX=9606 GN=CHD7 PE=1 SV=3 5.4 3434.6 - 355785 - - - -0.2775 - 3.961 0.707 - 317.5 1 2 0 -0.0007 22 0 0 0 1.46E+07 7.56E+07 - - - 9.6856 1 221125_WJC_METTL3_EV_vs_WT_F07.21580.21580.2 1.61E-12 15/52 R.GSSGGGC[160.03]FGGSSGGYGGLGGFGGGSFR.G "sp|P13645|K1C10_HUMAN,tr|A0A1B0GVI3|A0A1B0GVI3_HUMAN" 2 2341.9771 999 106735 21580 2 2341.98102 1171.9958 "Keratin, type I cytoskeletal 10 OS=Homo sapiens OX=9606 GN=KRT10 PE=1 SV=6" 8.22 3434.9 - 234700 - - - 1.6922 - 3.292 0.768 - 486.2 1 2 0 0.004 27 0 0 0 1.33E+07 0.00E+00 - - - 7.6415 1 221125_WJC_METTL3_EV_vs_WT_F07.21586.21586.4 1.88E-13 27/174 R.VPLVAPEDLRDDIIENAPTTHTEEYSGEEK.T "sp|O14744|ANM5_HUMAN,tr|G3V580|G3V580_HUMAN,tr|G3V2X6|G3V2X6_HUMAN,tr|G3V5L5|G3V5L5_HUMAN,tr|H0YJX6|H0YJX6_HUMAN" 5 3366.6103 3.01 106739 21586 4 3366.618879 842.6599 Protein arginine N-methyltransferase 5 OS=Homo sapiens OX=9606 GN=PRMT5 PE=1 SV=4 4.05 3435.7 - 1.12E+06 - - - 2.5405 - 4.293 0.647 - 282 1 2 1 0.0086 30 0 0 0 1.44E+09 4.78E+08 - - - 5.301 0.9989 221125_WJC_METTL3_EV_vs_WT_F07.21588.21588.3 7.87E-06 18/128 V.AGSSLTSFGTETSNSGTLPQSSAVGSAFTQDTR[166.11].S "sp|Q8ND56|LS14A_HUMAN,tr|A0A140TA76|A0A140TA76_HUMAN,tr|K7EMZ9|K7EMZ9_HUMAN" 3 3258.5152 0.79 106741 21588 3 3258.513483 1087.179 Protein LSM14 homolog A OS=Homo sapiens OX=9606 GN=LSM14A PE=1 SV=3 4.37 3435.9 - 559898 - - - -0.5248 - 3.714 0.591 - 215.2 1 1 0 -0.0017 33 0 0 0 9.87E+06 1.25E+07 - - - 8.1473 1 221125_WJC_METTL3_EV_vs_WT_F07.21591.21591.4 1.57E-18 34/162 R.TEVSFTLNEDLANIHDIGGKPASVSAPR.E sp|P13984|T2FB_HUMAN 1 2937.4832 1.11 106742 21591 4 2937.490607 735.3781 General transcription factor IIF subunit 2 OS=Homo sapiens OX=9606 GN=GTF2F2 PE=1 SV=2 4.75 3436.3 - 2.77E+06 - - - 2.5164 - 5.944 0.7 - 564.3 1 2 0 0.0074 28 0 0 0 5.59E+07 5.05E+07 - - - 5.8701 1 221125_WJC_METTL3_EV_vs_WT_F07.21593.21593.4 2.39E-10 20/138 K.LNC[160.03]QVIGASVDSHFC[160.03]HLAWVNTPK[136.11].K "sp|Q06830|PRDX1_HUMAN,tr|A0A0A0MSI0|A0A0A0MSI0_HUMAN" 2 2760.3356 0.35 106744 21593 4 2760.343801 691.0912 Peroxiredoxin-1 OS=Homo sapiens OX=9606 GN=PRDX1 PE=1 SV=1 6.9 3436.6 - 610710 - - - 2.9801 - 3.381 0.622 - 340.3 1 2 0 0.0082 24 0 0 0 1.20E+06 3.47E+06 - - - 5.0286 0.986 221125_WJC_METTL3_EV_vs_WT_F07.21596.21596.2 0.00389 18-Aug V.PALEIANAHR.K "sp|P10809|CH60_HUMAN,tr|A0A7I2V2X6|A0A7I2V2X6_HUMAN,tr|A0A7I2YQK6|A0A7I2YQK6_HUMAN,tr|A0A7I2V599|A0A7I2V599_HUMAN,tr|A0A7I2YQ71|A0A7I2YQ71_HUMAN,tr|A0A7I2V5M1|A0A7I2V5M1_HUMAN,tr|A0A7I2V5K3|A0A7I2V5K3_HUMAN,tr|A0A7I2V369|A0A7I2V369_HUMAN" 8 1090.5883 2.5 106747 21596 2 1090.587946 546.3014 "60 kDa heat shock protein, mitochondrial OS=Homo sapiens OX=9606 GN=HSPD1 PE=1 SV=2" 7.18 3437 - 111524 - - - -0.3631 - 2.068 0.38 - 191.8 1 1 0 -0.0004 10 0 0 0 4.59E+06 1.83E+06 - - - 3.8757 1 221125_WJC_METTL3_EV_vs_WT_F07.21599.21599.4 4.84E-13 25/174 R.VPLVAPEDLR[166.11]DDIIENAPTTHTEEYSGEEK[136.11].T "sp|O14744|ANM5_HUMAN,tr|G3V580|G3V580_HUMAN,tr|G3V2X6|G3V2X6_HUMAN,tr|G3V5L5|G3V5L5_HUMAN,tr|H0YJX6|H0YJX6_HUMAN" 5 3384.6328 3.01 106748 21599 4 3384.639959 847.1655 Protein arginine N-methyltransferase 5 OS=Homo sapiens OX=9606 GN=PRMT5 PE=1 SV=4 4.05 3437.4 - 1.41E+06 - - - 2.1163 - 4.162 0.63 - 345 1 2 1 0.0072 30 0 0 0 1.44E+09 4.77E+08 - - - 5.1439 1 221125_WJC_METTL3_EV_vs_WT_F07.21600.21600.3 3.67E-13 23/128 V.AGSSLTSFGTETSNSGTLPQSSAVGSAFTQDTR.S "sp|Q8ND56|LS14A_HUMAN,tr|A0A140TA76|A0A140TA76_HUMAN,tr|K7EMZ9|K7EMZ9_HUMAN" 3 3248.5069 0.79 106749 21600 3 3248.511824 1083.8429 Protein LSM14 homolog A OS=Homo sapiens OX=9606 GN=LSM14A PE=1 SV=3 4.37 3437.5 - 741226 - - - 1.5087 - 4.32 0.673 - 299.4 1 1 0 0.0049 33 0 0 0 9.87E+06 1.25E+07 - - - 9.4083 0.9994 221125_WJC_METTL3_EV_vs_WT_F07.21602.21602.4 3.81E-09 24/138 K.K[136.11]GVNLPGAAVDLPAVSEK[136.11]DIQDLK[136.11].F "sp|P14618|KPYM_HUMAN,tr|H3BQ34|H3BQ34_HUMAN,tr|B4DNK4|B4DNK4_HUMAN,tr|A0A804F6T5|A0A804F6T5_HUMAN,tr|H3BTN5|H3BTN5_HUMAN,tr|H3BR70|H3BR70_HUMAN,tr|A0A804F729|A0A804F729_HUMAN" 7 2500.3963 1.48 106751 21602 4 2500.408445 626.1064 Pyruvate kinase PKM OS=Homo sapiens OX=9606 GN=PKM PE=1 SV=4 4.68 3437.8 - 765963 - - - 4.8556 - 3.842 0.613 - 408.1 1 2 1 0.0121 24 0 0 0 5.54E+07 3.75E+07 - - - 4.9902 0.9996 221125_WJC_METTL3_EV_vs_WT_F07.21603.21603.4 0.000806 13/132 R.TLEELLKPPEDEAEHYKIPPLGK.H sp|O75528|TADA3_HUMAN 1 2645.3952 3.16 106752 21603 4 2645.399016 662.3561 Transcriptional adapter 3 OS=Homo sapiens OX=9606 GN=TADA3 PE=1 SV=1 4.7 3437.9 - 293303 - - - 1.4293 - 2.245 0.443 - 69.8 1 2 1 0.0038 23 0 0 0 7.97E+06 2.52E+06 - - - 3.3428 0.9979 221125_WJC_METTL3_EV_vs_WT_F07.21604.21604.4 0.044 8/150 K.DGQMLPGEDEPLHALVTANTMENVKK.A "sp|Q15637|SF01_HUMAN,tr|A0A7P0T9U7|A0A7P0T9U7_HUMAN" 2 2836.3735 0.77 106753 21604 4 2836.37607 710.1007 Splicing factor 1 OS=Homo sapiens OX=9606 GN=SF1 PE=1 SV=4 4.5 3438 - 276055 - - - 0.8955 - 1.792 0.269 - 28.1 1 2 0 0.0025 26 0 0 0 3.66E+06 4.78E+06 - - - 1.7507 0.9773 221125_WJC_METTL3_EV_vs_WT_F07.21609.21609.3 1.05E-10 19/72 K.SKELTTEIDNNIEQISSYK.S "sp|P13645|K1C10_HUMAN,tr|A0A1B0GVI3|A0A1B0GVI3_HUMAN" 2 2211.0907 58.11 106755 21609 3 2212.083777 738.0375 "Keratin, type I cytoskeletal 10 OS=Homo sapiens OX=9606 GN=KRT10 PE=1 SV=6" 4.41 3438.7 - 2.03E+07 - - - 449.1467 - 3.358 0.572 - 354.2 1 2 1 0.9931 19 0 0 0 6.20E+07 1.07E+06 - - - 7.6182 0.9466 221125_WJC_METTL3_EV_vs_WT_F07.21614.21614.4 0.0603 10/150 K.QLPDKWQHDLFDSGFGGGAGVETGGK.L "sp|Q86V81|THOC4_HUMAN,tr|E9PB61|E9PB61_HUMAN" 2 2702.2725 0.92 106760 21614 4 2702.28218 676.5754 THO complex subunit 4 OS=Homo sapiens OX=9606 GN=ALYREF PE=1 SV=3 4.66 3439.3 - 363085 - - - 3.5844 - 2.216 0.246 - 52.9 1 2 1 0.0097 26 0 0 0 4.32E+06 4.71E+06 - - - 1.6155 1 221125_WJC_METTL3_EV_vs_WT_F07.21615.21615.3 1.25E-07 25/100 K.QSHAASAAPQASSPPDYTMAWAEYYR.Q sp|Q96I24|FUBP3_HUMAN 1 2855.2609 2.02 106761 21615 3 2855.252624 952.7609 Far upstream element-binding protein 3 OS=Homo sapiens OX=9606 GN=FUBP3 PE=1 SV=2 5.32 3439.4 - 354806 - - - -2.9136 - 4.649 0.723 - 532.8 1 2 0 -0.0083 26 0 0 0 5.32E+08 2.63E+08 - - - 10.1337 0.9999 221125_WJC_METTL3_EV_vs_WT_F07.21621.21621.4 3.30E-09 28/138 K.KGVNLPGAAVDLPAVSEKDIQDLK.F "sp|P14618|KPYM_HUMAN,tr|H3BQ34|H3BQ34_HUMAN,tr|B4DNK4|B4DNK4_HUMAN,tr|A0A804F6T5|A0A804F6T5_HUMAN,tr|H3BTN5|H3BTN5_HUMAN,tr|H3BR70|H3BR70_HUMAN,tr|A0A804F729|A0A804F729_HUMAN" 7 2476.3537 1.48 106764 21621 4 2476.360106 620.0957 Pyruvate kinase PKM OS=Homo sapiens OX=9606 GN=PKM PE=1 SV=4 4.68 3440.1 - 1.12E+06 - - - 2.5853 - 4.084 0.602 - 512.1 1 2 1 0.0064 24 0 0 0 5.58E+07 3.76E+07 - - - 4.9157 1 221125_WJC_METTL3_EV_vs_WT_F07.21631.21631.3 3.66E-11 24/116 R.VPLVAPEDLRDDIIENAPTTHTEEYSGEEK.T "sp|O14744|ANM5_HUMAN,tr|G3V580|G3V580_HUMAN,tr|G3V2X6|G3V2X6_HUMAN,tr|G3V5L5|G3V5L5_HUMAN,tr|H0YJX6|H0YJX6_HUMAN" 5 3366.6103 3.66 106772 21631 3 3366.619665 1123.2107 Protein arginine N-methyltransferase 5 OS=Homo sapiens OX=9606 GN=PRMT5 PE=1 SV=4 4.05 3441.4 - 662751 - - - 2.774 - 4.056 0.712 - 389.3 1 2 1 0.0093 30 0 0 0 7.19E+07 1.97E+07 - - - 9.6969 0.9984 221125_WJC_METTL3_EV_vs_WT_F07.21634.21634.4 0.000737 15/150 K.QLPDK[136.11]WQHDLFDSGFGGGAGVETGGK[136.11].L "sp|Q86V81|THOC4_HUMAN,tr|E9PB61|E9PB61_HUMAN" 2 2718.3009 1.07 106775 21634 4 2718.29978 680.5825 THO complex subunit 4 OS=Homo sapiens OX=9606 GN=ALYREF PE=1 SV=3 4.66 3441.8 - 382490 - - - -0.4098 - 2.583 0.337 - 114.7 1 2 1 -0.0011 26 0 0 0 9.37E+06 8.73E+06 - - - 2.4583 0.9999 221125_WJC_METTL3_EV_vs_WT_F07.21636.21636.4 9.02E-06 12/150 K.QSHAASAAPQASSPPDYTMAWAEYYR.Q sp|Q96I24|FUBP3_HUMAN 1 2855.2609 1.44 106777 21636 4 2855.254891 714.8225 Far upstream element-binding protein 3 OS=Homo sapiens OX=9606 GN=FUBP3 PE=1 SV=2 5.32 3442 - 239117 - - - -2.1196 - 2.598 0.506 - 81.5 1 2 0 -0.0061 26 0 0 0 3.90E+07 2.72E+07 - - - 3.9297 1 221125_WJC_METTL3_EV_vs_WT_F07.21640.21640.3 1.24E-11 23/96 K.DR[166.11]PQEADGIDSVIVVDNVPQVGPDR[166.11].L "sp|P55884|EIF3B_HUMAN,tr|C9JZG1|C9JZG1_HUMAN" 2 2709.3473 1.38 106779 21640 3 2709.348558 904.123 Eukaryotic translation initiation factor 3 subunit B OS=Homo sapiens OX=9606 GN=EIF3B PE=1 SV=3 3.9 3442.5 - 864810 - - - 0.4728 - 4.153 0.612 - 364.5 1 2 0 0.0013 25 0 0 0 7.72E+07 5.60E+07 - - - 8.6386 1 221125_WJC_METTL3_EV_vs_WT_F07.21641.21641.3 0.0888 15/56 R.GFGFVTFDDHDPVDK[136.11].L "sp|P22626|ROA2_HUMAN,tr|A0A7I2V4N0|A0A7I2V4N0_HUMAN,tr|A0A024RA28|A0A024RA28_HUMAN,tr|A0A7I2V4N1|A0A7I2V4N1_HUMAN,tr|A0A7I2V4I6|A0A7I2V4I6_HUMAN,tr|A0A087WUI2|A0A087WUI2_HUMAN,tr|A0A7I2V4S4|A0A7I2V4S4_HUMAN,tr|A0A7I2V323|A0A7I2V323_HUMAN,tr|A0A7I2V3P1|A0A7I2V3P1_HUMAN,tr|A0A7I2V3P7|A0A7I2V3P7_HUMAN" 10 1702.7719 1.38 106780 21641 3 1702.773302 568.5979 Heterogeneous nuclear ribonucleoproteins A2\B1 OS=Homo sapiens OX=9606 GN=HNRNPA2B1 PE=1 SV=2 4.13 3442.6 - 441697 - - - 0.8521 - 2.352 0.496 - 190.5 1 2 0 0.0015 15 0 0 0 1.03E+07 7.47E+06 - - - 6.3012 1 221125_WJC_METTL3_EV_vs_WT_F07.21644.21644.3 2.89E-09 16/56 R.GFGFVTFDDHDPVDK.L "sp|P22626|ROA2_HUMAN,tr|A0A7I2V4N0|A0A7I2V4N0_HUMAN,tr|A0A024RA28|A0A024RA28_HUMAN,tr|A0A7I2V4N1|A0A7I2V4N1_HUMAN,tr|A0A7I2V4I6|A0A7I2V4I6_HUMAN,tr|A0A087WUI2|A0A087WUI2_HUMAN,tr|A0A7I2V4S4|A0A7I2V4S4_HUMAN,tr|A0A7I2V323|A0A7I2V323_HUMAN,tr|A0A7I2V3P1|A0A7I2V3P1_HUMAN,tr|A0A7I2V3P7|A0A7I2V3P7_HUMAN" 10 1694.7577 1.38 106783 21644 3 1694.761291 565.9265 Heterogeneous nuclear ribonucleoproteins A2\B1 OS=Homo sapiens OX=9606 GN=HNRNPA2B1 PE=1 SV=2 4.13 3443 - 495610 - - - 2.1478 - 2.811 0.647 - 206.9 1 2 0 0.0036 15 0 0 0 1.03E+07 7.47E+06 - - - 8.4493 1 221125_WJC_METTL3_EV_vs_WT_F07.21648.21648.3 1.11E-12 31/100 K.QSHAASAAPQASSPPDYTMAWAEYYR[166.11].Q sp|Q96I24|FUBP3_HUMAN 1 2865.2692 2.02 106785 21648 3 2865.268592 956.097 Far upstream element-binding protein 3 OS=Homo sapiens OX=9606 GN=FUBP3 PE=1 SV=2 5.32 3443.5 - 1.44E+06 - - - -0.2167 - 5.014 0.666 - 948 1 2 0 -0.0006 26 0 0 0 5.32E+08 2.63E+08 - - - 9.6742 1 221125_WJC_METTL3_EV_vs_WT_F07.21657.21657.4 0.000642 10/108 R.GLLQDDAHPTLVTYADHSK[136.11].L "sp|Q86U44|MTA70_HUMAN,tr|F5H6D8|F5H6D8_HUMAN,tr|H0YFV6|H0YFV6_HUMAN,tr|B4DTN4|B4DTN4_HUMAN" 4 2088.0367 0.01 106792 21657 4 2088.037798 523.0165 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 5.13 3444.7 - 286246 - - - 0.51 - 2.006 0.485 - 87 1 2 0 0.0011 19 0 0 0 1.99E+05 2.37E+07 - - - 3.6826 1 221125_WJC_METTL3_EV_vs_WT_F07.21664.21664.4 9.41E-08 18/216 K.TAPLPPASQTTPLQMALNGKPAPPPQSQSPEVEQLGR.V "sp|P52948|NUP98_HUMAN,tr|A0A3B3ITD8|A0A3B3ITD8_HUMAN" 2 3832.9782 2.67 106797 21664 4 3832.978461 959.2518 Nuclear pore complex protein Nup98-Nup96 OS=Homo sapiens OX=9606 GN=NUP98 PE=1 SV=4 5.81 3445.6 - 425997 - - - 0.0751 - 2.887 0.536 - 83 1 2 0 0.0003 37 0 0 0 1.64E+07 6.16E+06 - - - 4.2021 1 221125_WJC_METTL3_EV_vs_WT_F07.21665.21665.3 7.19E-11 15/132 R.AGAGAPVVGSGSSGGGNAFTGLGPVSTLPSLHGK[136.11].Q "sp|Q9NNW5|WDR6_HUMAN,tr|E9PDU5|E9PDU5_HUMAN,tr|A0A087X295|A0A087X295_HUMAN" 3 2971.5243 1.14 106798 21665 3 2971.527338 991.5154 WD repeat-containing protein 6 OS=Homo sapiens OX=9606 GN=WDR6 PE=1 SV=1 8.8 3445.8 - 383739 - - - 1.023 - 2.859 0.68 - 123.3 1 2 0 0.003 34 0 0 0 1.91E+07 1.67E+07 - - - 8.5372 1 221125_WJC_METTL3_EV_vs_WT_F07.21678.21678.3 8.23E-08 29/96 K.DRPQEADGIDSVIVVDNVPQVGPDR.L "sp|P55884|EIF3B_HUMAN,tr|C9JZG1|C9JZG1_HUMAN" 2 2689.3307 1.38 106804 21678 3 2689.333752 897.4509 Eukaryotic translation initiation factor 3 subunit B OS=Homo sapiens OX=9606 GN=EIF3B PE=1 SV=3 3.9 3447.6 - 3.96E+06 - - - 1.1211 - 4.551 0.648 - 659.7 1 2 0 0.003 25 0 0 0 7.72E+07 5.60E+07 - - - 9.25 0.9687 221125_WJC_METTL3_EV_vs_WT_F07.21687.21687.4 0.000304 12/156 R.EPGK[136.11]FDLVYHNENGAEVVEYAVTQESK[136.11].L sp|P38432|COIL_HUMAN 1 3067.4746 0.6 106811 21687 4 3068.480369 767.8759 Coilin OS=Homo sapiens OX=9606 GN=COIL PE=1 SV=1 4.41 3448.7 - 458359 - - - 327.8945 - 1.874 0.396 - 52.4 1 2 1 1.0058 27 0 0 0 9.92E+06 1.66E+07 - - - 2.5907 0.9999 221125_WJC_METTL3_EV_vs_WT_F07.21688.21688.4 0.00846 Dec-84 K.FGHEFLEFEFRPDGK.L "sp|Q96A72|MGN2_HUMAN,sp|P61326|MGN_HUMAN,tr|F5H6N1|F5H6N1_HUMAN" 3 1853.8737 2 106812 21688 4 1853.874944 464.4757 Protein mago nashi homolog 2 OS=Homo sapiens OX=9606 GN=MAGOHB PE=1 SV=1 4.83 3448.9 - 348061 - - - 0.6797 - 1.811 0.423 - 70.8 1 2 0 0.0013 15 0 0 0 5.86E+06 2.94E+06 - - - 3.1199 1 221125_WJC_METTL3_EV_vs_WT_F07.21694.21694.3 2.81E-15 21/132 R.AGAGAPVVGSGSSGGGNAFTGLGPVSTLPSLHGK.Q "sp|Q9NNW5|WDR6_HUMAN,tr|E9PDU5|E9PDU5_HUMAN,tr|A0A087X295|A0A087X295_HUMAN" 3 2963.5101 1.14 106815 21694 3 2963.505755 988.844 WD repeat-containing protein 6 OS=Homo sapiens OX=9606 GN=WDR6 PE=1 SV=1 8.8 3449.6 - 704243 - - - -1.4655 - 3.626 0.715 - 314.5 1 2 0 -0.0043 34 0 0 0 1.91E+07 1.67E+07 - - - 9.4739 1 221125_WJC_METTL3_EV_vs_WT_F07.21697.21697.3 3.53E-06 19/124 K.VGGTNLGAPGAFGQSPFSQPPAPPHQNTFPPR[166.11].S sp|Q96I24|FUBP3_HUMAN 1 3237.5984 2.7 106816 21697 3 3237.596056 1080.2067 Far upstream element-binding protein 3 OS=Homo sapiens OX=9606 GN=FUBP3 PE=1 SV=2 9.73 3450 - 493796 - - - -0.7085 - 3.29 0.601 - 173.4 1 2 0 -0.0023 32 0 0 0 6.90E+07 2.56E+07 - - - 7.9797 1 221125_WJC_METTL3_EV_vs_WT_F07.21698.21698.4 4.84E-12 26/204 R.YGPQYGHPPPPPPPPEYGPHADSPVLMVYGLDQSK.M "sp|P14866|HNRPL_HUMAN,tr|A0A3B3ITJ4|A0A3B3ITJ4_HUMAN,tr|M0QXS5|M0QXS5_HUMAN" 3 3783.8032 1.62 106817 21698 4 3783.8005 946.9581 Heterogeneous nuclear ribonucleoprotein L OS=Homo sapiens OX=9606 GN=HNRNPL PE=1 SV=2 5.21 3450.1 - 627252 - - - -0.7054 - 4.598 0.667 - 345.2 1 2 0 -0.0027 35 0 0 0 1.69E+08 1.04E+08 - - - 5.4831 0.9999 221125_WJC_METTL3_EV_vs_WT_F07.21703.21703.4 2.95E-07 23/126 K.LNC[160.03]FLEQDLKLDIPTGTTPQRK.S "sp|P52732|KIF11_HUMAN,tr|A0A7I2V3A9|A0A7I2V3A9_HUMAN" 2 2586.3476 6.13 106820 21703 4 2586.34986 647.5942 Kinesin-like protein KIF11 OS=Homo sapiens OX=9606 GN=KIF11 PE=1 SV=2 6.11 3450.8 - 1.09E+06 - - - 0.8843 - 4.326 0.594 - 299.9 1 2 1 0.0023 22 0 0 0 5.12E+07 8.35E+06 - - - 4.8748 1 221125_WJC_METTL3_EV_vs_WT_F07.21706.21706.4 1.86E-08 21/216 K.EAATQEDPEQLPELEAHGVSESEGEERPVAEEEILLR.E "sp|Q9BVJ6|UT14A_HUMAN,tr|X6RJY0|X6RJY0_HUMAN" 2 4114.9455 2.97 106822 21706 4 4114.941584 1029.7436 U3 small nucleolar RNA-associated protein 14 homolog A OS=Homo sapiens OX=9606 GN=UTP14A PE=1 SV=1 3.94 3451.1 - 567340 - - - -0.9448 - 3.565 0.619 - 100.7 1 2 0 -0.0039 37 0 0 0 3.33E+07 1.12E+07 - - - 4.9854 1 221125_WJC_METTL3_EV_vs_WT_F07.21707.21707.3 1.94E-13 17/116 R.VPLVAPEDLR[166.11]DDIIENAPTTHTEEYSGEEK[136.11].T "sp|O14744|ANM5_HUMAN,tr|G3V580|G3V580_HUMAN,tr|G3V2X6|G3V2X6_HUMAN,tr|G3V5L5|G3V5L5_HUMAN,tr|H0YJX6|H0YJX6_HUMAN" 5 3384.6328 3.66 106823 21707 3 3384.635175 1129.2182 Protein arginine N-methyltransferase 5 OS=Homo sapiens OX=9606 GN=PRMT5 PE=1 SV=4 4.05 3451.3 - 662808 - - - 0.7029 - 3.52 0.731 - 148.6 1 2 1 0.0024 30 0 0 0 7.19E+07 1.97E+07 - - - 9.5845 1 221125_WJC_METTL3_EV_vs_WT_F07.21714.21714.4 9.98E-13 27/240 R.TGSLKPNPASPLPASPYGGPTPASYTTASTPAGPAFPVQVK.V sp|Q15654|TRIP6_HUMAN 1 3979.0367 0.61 106827 21714 4 3979.036986 995.7665 Thyroid receptor-interacting protein 6 OS=Homo sapiens OX=9606 GN=TRIP6 PE=1 SV=3 9.52 3452.1 - 610921 - - - 0.0633 - 3.591 0.74 - 217.5 1 2 0 0.0003 41 0 0 0 7.86E+06 1.29E+07 - - - 6.0341 0.9999 221125_WJC_METTL3_EV_vs_WT_F07.21718.21718.2 0.000481 18-Sep R.EC[160.03]LNLWGYER[166.11].V sp|Q86U44|MTA70_HUMAN 1 1348.6109 0.001 106829 21718 2 1348.61036 675.3127 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 4.53 3452.7 - 2.00E+06 - - - -0.4308 - 1.87 0.527 - 356.1 1 2 0 -0.0006 10 0 0 0 0.00E+00 6.78E+07 - - - 4.6804 1 221125_WJC_METTL3_EV_vs_WT_F07.21725.21725.3 2.62E-12 23/120 R.GSEGK[136.11]PSLTLPASAPGPEEALTTVTVAPAPR[166.11].R sp|P48634|PRC2A_HUMAN 1 3018.5993 1.41 106833 21725 3 3018.60362 1007.207 Protein PRRC2A OS=Homo sapiens OX=9606 GN=PRRC2A PE=1 SV=3 4.79 3453.6 - 536002 - - - 1.4474 - 4.163 0.679 - 495.9 1 2 0 0.0044 31 0 0 0 1.18E+08 8.42E+07 - - - 9.3902 1 221125_WJC_METTL3_EV_vs_WT_F07.21743.21743.3 1.59E-13 26/120 R.GSEGKPSLTLPASAPGPEEALTTVTVAPAPR.R sp|P48634|PRC2A_HUMAN 1 3000.5768 1.41 106842 21743 3 3000.57629 1001.1995 Protein PRRC2A OS=Homo sapiens OX=9606 GN=PRRC2A PE=1 SV=3 4.79 3456.1 - 1.53E+06 - - - -0.1636 - 4.561 0.688 - 643.7 1 2 0 -0.0005 31 0 0 0 1.18E+08 8.42E+07 - - - 9.7017 1 221125_WJC_METTL3_EV_vs_WT_F07.21757.21757.3 5.32E-11 18/80 R.LASYLDKVQALEEANNDLENK.L sp|P35527|K1C9_HUMAN 1 2376.1809 999 106849 21757 3 2376.174217 793.0676 "Keratin, type I cytoskeletal 9 OS=Homo sapiens OX=9606 GN=KRT9 PE=1 SV=3" 4.18 3457.7 - 1.04E+06 - - - -2.8062 - 3.945 0.635 - 357.8 1 2 1 -0.0067 21 0 0 0 1.20E+07 0.00E+00 - - - 8.9082 1 221125_WJC_METTL3_EV_vs_WT_F07.21772.21772.4 1.48E-09 15/222 R.AQPGAAPGIYQQSAEASSSQGTAANSQSYTIMSPAVLK.S sp|P98175|RBM10_HUMAN 1 3766.8108 4.52 106858 21772 4 3766.80109 942.71 RNA-binding protein 10 OS=Homo sapiens OX=9606 GN=RBM10 PE=1 SV=3 6.04 3459.6 - 2.40E+06 - - - -2.5865 - 3.004 0.622 - 42.6 1 2 0 -0.0097 38 0 0 0 8.40E+07 1.86E+07 - - - 4.9579 0.9996 221125_WJC_METTL3_EV_vs_WT_F07.21782.21782.2 0.00047 22-Oct K.DAGTIAGLNVLR[166.11].L "sp|P11142|HSP7C_HUMAN,tr|E9PQQ4|E9PQQ4_HUMAN,tr|E9PKE3|E9PKE3_HUMAN,tr|E9PN89|E9PN89_HUMAN,tr|E9PLF4|E9PLF4_HUMAN,tr|E9PI65|E9PI65_HUMAN,tr|E9PK54|E9PK54_HUMAN,tr|E9PQK7|E9PQK7_HUMAN" 8 1208.6753 1.71 106862 21782 2 1208.672777 605.3449 Heat shock cognate 71 kDa protein OS=Homo sapiens OX=9606 GN=HSPA8 PE=1 SV=1 5.84 3460.9 - 446775 - - - -2.051 - 2.126 0.428 - 282 1 2 0 -0.0025 12 0 0 0 4.80E+07 2.81E+07 - - - 4.186 0.9999 221125_WJC_METTL3_EV_vs_WT_F07.21784.21784.4 4.73E-08 29/186 K.VGGTNLGAPGAFGQSPFSQPPAPPHQNTFPPR.S sp|Q96I24|FUBP3_HUMAN 1 3227.5901 2.5 106863 21784 4 3227.581648 807.9048 Far upstream element-binding protein 3 OS=Homo sapiens OX=9606 GN=FUBP3 PE=1 SV=2 9.73 3461.1 - 2.82E+06 - - - -2.6125 - 3.302 0.542 - 241.6 1 2 0 -0.0084 32 0 0 0 1.14E+08 4.55E+07 - - - 4.3019 1 221125_WJC_METTL3_EV_vs_WT_F07.21786.21786.4 4.97E-10 21/204 R.YGPQYGHPPPPPPPPEYGPHADSPVLMVYGLDQSK[136.11].M "sp|P14866|HNRPL_HUMAN,tr|A0A3B3ITJ4|A0A3B3ITJ4_HUMAN,tr|M0QXS5|M0QXS5_HUMAN" 3 3791.8174 2.52 106864 21786 4 3791.817808 948.9616 Heterogeneous nuclear ribonucleoprotein L OS=Homo sapiens OX=9606 GN=HNRNPL PE=1 SV=2 5.21 3461.3 - 1.50E+06 - - - 0.1158 - 4.483 0.571 - 204.8 1 2 0 0.0004 35 0 0 0 1.10E+08 4.36E+07 - - - 4.6406 1 221125_WJC_METTL3_EV_vs_WT_F07.21789.21789.4 4.83E-17 31/186 K.LVSQTGPVHAPIFTMSVEVDGNSFEASGPSKK.T sp|Q12906|ILF3_HUMAN 1 3315.6445 1.18 106865 21789 4 3315.636041 829.9184 Interleukin enhancer-binding factor 3 OS=Homo sapiens OX=9606 GN=ILF3 PE=1 SV=3 5.45 3461.7 - 1.67E+06 - - - -2.5642 - 5.768 0.645 - 624.9 1 2 0 -0.0085 32 0 0 0 1.29E+08 1.10E+08 - - - 5.3668 0.9994 221125_WJC_METTL3_EV_vs_WT_F07.21790.21790.2 7.51E-05 13/22 K.DAGTIAGLNVLR.L "sp|P11142|HSP7C_HUMAN,tr|E9PQQ4|E9PQQ4_HUMAN,tr|E9PKE3|E9PKE3_HUMAN,tr|E9PN89|E9PN89_HUMAN,tr|E9PLF4|E9PLF4_HUMAN,tr|E9PI65|E9PI65_HUMAN,tr|E9PK54|E9PK54_HUMAN,tr|E9PQK7|E9PQK7_HUMAN" 8 1198.667 1.71 106866 21790 2 1198.662922 600.3408 Heat shock cognate 71 kDa protein OS=Homo sapiens OX=9606 GN=HSPA8 PE=1 SV=1 5.84 3461.9 - 919278 - - - -3.3904 - 2.602 0.517 - 625.1 1 2 0 -0.0041 12 0 0 0 4.80E+07 2.81E+07 - - - 5.3744 1 221125_WJC_METTL3_EV_vs_WT_F07.21794.21794.3 1.33E-07 27/124 K.VGGTNLGAPGAFGQSPFSQPPAPPHQNTFPPR.S sp|Q96I24|FUBP3_HUMAN 1 3227.5901 2.81 106868 21794 3 3227.583201 1076.8706 Far upstream element-binding protein 3 OS=Homo sapiens OX=9606 GN=FUBP3 PE=1 SV=2 9.73 3462.4 - 1.72E+06 - - - -2.1313 - 4.039 0.607 - 398.9 1 2 0 -0.0069 32 0 0 0 1.11E+08 3.94E+07 - - - 8.5172 1 221125_WJC_METTL3_EV_vs_WT_F07.21808.21808.4 3.46E-12 33/186 K.LVSQTGPVHAPIFTMSVEVDGNSFEASGPSK[136.11]K[136.11].T sp|Q12906|ILF3_HUMAN 1 3331.6729 1.18 106874 21808 4 3331.663399 833.9255 Interleukin enhancer-binding factor 3 OS=Homo sapiens OX=9606 GN=ILF3 PE=1 SV=3 5.45 3464.2 - 3.45E+06 - - - -2.8646 - 5.277 0.584 - 596.4 1 2 0 -0.0095 32 0 0 0 1.29E+08 1.10E+08 - - - 4.8087 0.831 221125_WJC_METTL3_EV_vs_WT_F07.21810.21810.4 0.00343 11/120 R.K[136.11]IELFGR[166.11]PHNVQPNWITLGNQ.L sp|Q86U44|MTA70_HUMAN 1 2478.3251 0.01 106876 21810 4 2478.317926 620.5885 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 8.75 3464.4 - 1.01E+06 - - - -2.8874 - 2.327 0.318 - 60.7 1 1 0 -0.0072 21 0 0 0 3.21E+06 4.34E+08 - - - 2.2711 0.9999 221125_WJC_METTL3_EV_vs_WT_F07.21820.21820.3 1.90E-06 16/48 R.KVESLQEEIAFLK.K "sp|P08670|VIME_HUMAN,tr|B0YJC5|B0YJC5_HUMAN,tr|B0YJC4|B0YJC4_HUMAN" 3 1532.845 1.82 106881 21820 3 1532.838512 511.9556 Vimentin OS=Homo sapiens OX=9606 GN=VIM PE=1 SV=4 4.79 3465.7 - 557153 - - - -4.2392 - 3.29 0.543 - 633 1 2 0 -0.0065 13 0 0 0 1.55E+07 8.50E+06 - - - 7.821 1 221125_WJC_METTL3_EV_vs_WT_F07.21822.21822.3 1.78E-06 31/124 R.GAPAADDDKGPQQLLLPPPPPPPPAAALDGAK.A sp|P55316|FOXG1_HUMAN 1 3081.6135 1.89 106882 21822 3 3081.596033 1028.2118 Forkhead box protein G1 OS=Homo sapiens OX=9606 GN=FOXG1 PE=1 SV=2 4.14 3465.9 - 992690 - - - -5.6685 - 5.026 0.673 - 796.6 1 2 1 -0.0175 32 0 0 0 6.73E+07 3.55E+07 - - - 9.7531 0.9999 221125_WJC_METTL3_EV_vs_WT_F07.21823.21823.4 2.53E-05 28/186 R.GAPAADDDKGPQQLLLPPPPPPPPAAALDGAK.A sp|P55316|FOXG1_HUMAN 1 3081.6135 2.61 106883 21823 4 3081.611746 771.4107 Forkhead box protein G1 OS=Homo sapiens OX=9606 GN=FOXG1 PE=1 SV=2 4.14 3466 - 1.02E+06 - - - -0.5695 - 4.229 0.521 - 488.5 1 2 1 -0.0018 32 0 0 0 3.66E+07 1.40E+07 - - - 4.1957 1 221125_WJC_METTL3_EV_vs_WT_F07.21829.21829.3 9.69E-06 23/120 R.TEDSIRDYEDGMEVDTTPTVAGQFEDADVDH.- "sp|P54105|ICLN_HUMAN,tr|J3KN38|J3KN38_HUMAN,tr|E9PMI6|E9PMI6_HUMAN" 3 3456.4423 3.99 106886 21829 3 3456.440852 1153.1547 Methylosome subunit pICln OS=Homo sapiens OX=9606 GN=CLNS1A PE=1 SV=1 3.63 3466.8 - 1.20E+06 - - - -0.4288 - 5.044 0.744 - 401.1 1 2 1 -0.0015 31 0 0 0 4.39E+07 1.10E+07 - - - 10.5573 1 221125_WJC_METTL3_EV_vs_WT_F07.21831.21831.3 4.93E-11 24/104 K.DHTPSQELALTQSVGGDSSADR[166.11]LFPPQ.W "sp|Q86U44|MTA70_HUMAN,tr|H0YFV6|H0YFV6_HUMAN" 2 2862.3659 0 106887 21831 3 2862.359256 955.1293 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 4.22 3467.1 - 7.50E+06 - - - -2.3386 - 4.101 0.605 - 242.6 1 1 1 -0.0067 27 0 0 0 1.31E+05 3.40E+08 - - - 8.53 1 221125_WJC_METTL3_EV_vs_WT_F07.21837.21837.3 5.75E-05 Oct-48 R.K[136.11]VESLQEEIAFLK[136.11].K "sp|P08670|VIME_HUMAN,tr|B0YJC5|B0YJC5_HUMAN,tr|B0YJC4|B0YJC4_HUMAN" 3 1548.8734 1.84 106890 21837 3 1548.872863 517.2984 Vimentin OS=Homo sapiens OX=9606 GN=VIM PE=1 SV=4 4.79 3467.8 - 287612 - - - -0.3532 - 2.251 0.475 - 156.6 1 2 0 -0.0005 13 0 0 0 1.55E+07 8.39E+06 - - - 6.0355 1 221125_WJC_METTL3_EV_vs_WT_F07.21840.21840.4 2.04E-07 21/144 K.KVEHEISEGNVATAAAAALASAATK.A sp|Q92922|SMRC1_HUMAN 1 2409.25 3.26 106891 21840 4 2409.250737 603.3198 SWI\SNF complex subunit SMARCC1 OS=Homo sapiens OX=9606 GN=SMARCC1 PE=1 SV=3 5.5 3468.2 - 620573 - - - 0.3196 - 3.915 0.515 - 302.7 1 2 0 0.0008 25 0 0 0 2.41E+08 7.41E+07 - - - 4.1425 1 221125_WJC_METTL3_EV_vs_WT_F07.21843.21843.4 9.87E-08 16/180 R.TEDSIRDYEDGMEVDTTPTVAGQFEDADVDH.- "sp|P54105|ICLN_HUMAN,tr|J3KN38|J3KN38_HUMAN,tr|E9PMI6|E9PMI6_HUMAN" 3 3456.4423 3.8 106893 21843 4 3456.446876 865.1179 Methylosome subunit pICln OS=Homo sapiens OX=9606 GN=CLNS1A PE=1 SV=1 3.63 3468.5 - 535009 - - - 1.3141 - 3.775 0.681 - 130.7 1 2 1 0.0045 31 0 0 0 1.22E+07 3.22E+06 - - - 5.5559 0.989 221125_WJC_METTL3_EV_vs_WT_F07.21844.21844.3 1.85E-07 18/80 R.K[136.11]IELFGR[166.11]PHNVQPNWITLGNQ.L sp|Q86U44|MTA70_HUMAN 1 2478.3251 0.001 106894 21844 3 2478.319338 827.1156 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 8.75 3468.7 - 1.38E+06 - - - -2.3177 - 3.131 0.422 - 396.3 1 1 0 -0.0057 21 0 0 0 0.00E+00 1.29E+08 - - - 5.9796 0.9938 221125_WJC_METTL3_EV_vs_WT_F07.21847.21847.4 5.05E-06 20/144 K.K[136.11]VEHEISEGNVATAAAAALASAATK[136.11].A sp|Q92922|SMRC1_HUMAN 1 2425.2784 3.26 106895 21847 4 2426.271774 607.3269 SWI\SNF complex subunit SMARCC1 OS=Homo sapiens OX=9606 GN=SMARCC1 PE=1 SV=3 5.5 3469.1 - 443140 - - - 409.6054 - 3.702 0.542 - 269.4 1 2 0 0.9934 25 0 0 0 2.41E+08 7.40E+07 - - - 4.0848 0.9997 221125_WJC_METTL3_EV_vs_WT_F07.21848.21848.4 1.30E-05 13/102 R.NKDHPAFAPLYFPMELHR.K "sp|P30519|HMOX2_HUMAN,tr|I3L276|I3L276_HUMAN,tr|I3L159|I3L159_HUMAN,tr|I3L463|I3L463_HUMAN,tr|I3L4P8|I3L4P8_HUMAN,tr|A0A1B0GXH0|A0A1B0GXH0_HUMAN,tr|A0A087WT44|A0A087WT44_HUMAN,tr|I3L1F5|I3L1F5_HUMAN" 8 2182.0782 1.14 106896 21848 4 2182.085305 546.5268 Heme oxygenase 2 OS=Homo sapiens OX=9606 GN=HMOX2 PE=1 SV=2 6.92 3469.2 - 481416 - - - 3.2492 - 3.271 0.549 - 118.2 1 2 1 0.0071 18 0 0 0 6.94E+06 6.08E+06 - - - 4.4085 0.9997 221125_WJC_METTL3_EV_vs_WT_F07.21857.21857.3 2.26E-05 17/72 K.SKELTTEIDNNIEQISSYK.S "sp|P13645|K1C10_HUMAN,tr|A0A1B0GVI3|A0A1B0GVI3_HUMAN" 2 2211.0907 12.73 106902 21857 3 2211.094839 738.0375 "Keratin, type I cytoskeletal 10 OS=Homo sapiens OX=9606 GN=KRT10 PE=1 SV=6" 4.41 3470.4 - 1.32E+06 - - - 1.8841 - 2.801 0.486 - 273.9 1 2 1 0.0042 19 0 0 0 1.07E+08 8.38E+06 - - - 6.4877 1 221125_WJC_METTL3_EV_vs_WT_F07.21858.21858.4 0.000157 26/186 K.VGGTNLGAPGAFGQSPFSQPPAPPHQNTFPPR[166.11].S sp|Q96I24|FUBP3_HUMAN 1 3237.5984 2.64 106903 21858 4 3237.595662 810.4069 Far upstream element-binding protein 3 OS=Homo sapiens OX=9606 GN=FUBP3 PE=1 SV=2 9.73 3470.5 - 1.01E+06 - - - -0.8302 - 4.236 0.542 - 226.8 1 2 0 -0.0027 32 0 0 0 6.74E+07 2.55E+07 - - - 4.3787 0.9999 221125_WJC_METTL3_EV_vs_WT_F07.21860.21860.4 5.47E-06 17/108 K.K[136.11]AQDEGLLSDVVPFK[136.11]VPGK[136.11].D "sp|P55084|ECHB_HUMAN,tr|F5GZQ3|F5GZQ3_HUMAN" 2 2050.1525 0.87 106905 21860 4 2050.15467 513.5454 "Trifunctional enzyme subunit beta, mitochondrial OS=Homo sapiens OX=9606 GN=HADHB PE=1 SV=3" 6.12 3470.8 - 482764 - - - 1.0624 - 3.227 0.494 - 220.2 1 2 1 0.0022 19 0 0 0 3.22E+07 3.70E+07 - - - 3.9215 1 221125_WJC_METTL3_EV_vs_WT_F07.21863.21863.3 3.17E-06 25/84 H.SALSSASTSSHNLQSIFNIGSR.G "sp|P43243|MATR3_HUMAN,tr|A8MXP9|A8MXP9_HUMAN,tr|D6R991|D6R991_HUMAN,tr|D6REK4|D6REK4_HUMAN,tr|A0A0R4J2E8|A0A0R4J2E8_HUMAN,tr|D6RCM3|D6RCM3_HUMAN,tr|D6R8Z5|D6R8Z5_HUMAN,tr|D6REM6|D6REM6_HUMAN" 8 2263.1193 2.91 106906 21863 3 2263.121598 755.3804 Matrin-3 OS=Homo sapiens OX=9606 GN=MATR3 PE=1 SV=2 9.49 3471.2 - 1.30E+06 - - - 1.0212 - 4.421 0.593 - 927.4 1 1 0 0.0023 22 0 0 0 1.60E+08 5.49E+07 - - - 8.6747 1 221125_WJC_METTL3_EV_vs_WT_F07.21864.21864.3 1.80E-18 28/120 R.TEDSIR[166.11]DYEDGMEVDTTPTVAGQFEDADVDH.- "sp|P54105|ICLN_HUMAN,tr|J3KN38|J3KN38_HUMAN,tr|E9PMI6|E9PMI6_HUMAN" 3 3466.4506 3.99 106907 21864 3 3466.445716 1156.4908 Methylosome subunit pICln OS=Homo sapiens OX=9606 GN=CLNS1A PE=1 SV=1 3.63 3471.3 - 633057 - - - -1.4101 - 5.328 0.79 - 846.7 1 2 1 -0.0049 31 0 0 0 4.39E+07 1.10E+07 - - - 11.1953 0.9999 221125_WJC_METTL3_EV_vs_WT_F07.21865.21865.4 3.88E-08 17/108 K.KAQDEGLLSDVVPFKVPGK.D "sp|P55084|ECHB_HUMAN,tr|F5GZQ3|F5GZQ3_HUMAN" 2 2026.1099 0.87 106908 21865 4 2026.109355 507.5347 "Trifunctional enzyme subunit beta, mitochondrial OS=Homo sapiens OX=9606 GN=HADHB PE=1 SV=3" 6.12 3471.5 - 639327 - - - -0.265 - 3.077 0.531 - 243 1 2 1 -0.0005 19 0 0 0 3.22E+07 3.70E+07 - - - 4.2279 0.9999 221125_WJC_METTL3_EV_vs_WT_F07.21871.21871.3 6.31E-07 22/80 K.QISNLQQSISDAEQRGENALK.D sp|P04264|K2C1_HUMAN 1 2328.167 20045.17 106912 21871 3 2328.167937 777.0629 "Keratin, type II cytoskeletal 1 OS=Homo sapiens OX=9606 GN=KRT1 PE=1 SV=6" 4.68 3472.2 - 1.45E+07 - - - 0.4171 - 3.902 0.559 - 413.2 1 2 1 0.001 21 0 0 0 4.90E+09 2.44E+05 - - - 8.0361 1 221125_WJC_METTL3_EV_vs_WT_F07.21876.21876.3 3.21E-12 28/96 K.KVEHEISEGNVATAAAAALASAATK.A sp|Q92922|SMRC1_HUMAN 1 2409.25 9.04 106915 21876 3 2409.253298 804.0906 SWI\SNF complex subunit SMARCC1 OS=Homo sapiens OX=9606 GN=SMARCC1 PE=1 SV=3 5.5 3472.9 - 935482 - - - 1.3826 - 5.171 0.665 - 1247.9 1 2 0 0.0033 25 0 0 0 8.07E+07 8.93E+06 - - - 9.7333 0.9989 221125_WJC_METTL3_EV_vs_WT_F07.21890.21890.3 2.44E-09 Nov-92 K.NQSQGYNQWQQGQFWGQKPWSQHY.H "sp|Q00839|HNRPU_HUMAN,tr|A0A1W2PPL4|A0A1W2PPL4_HUMAN,tr|Q5RI18|Q5RI18_HUMAN,tr|A0A1W2PP35|A0A1W2PP35_HUMAN,tr|A0A1W2PPH7|A0A1W2PPH7_HUMAN,tr|A0A1X7SBS1|A0A1X7SBS1_HUMAN" 6 3009.3331 1.07 106925 21890 3 3009.335991 1004.1183 Heterogeneous nuclear ribonucleoprotein U OS=Homo sapiens OX=9606 GN=HNRNPU PE=1 SV=6 8.5 3474.6 - 504151 - - - 0.9484 - 2.879 0.66 - 82.4 1 1 0 0.0029 24 0 0 0 9.98E+06 9.30E+06 - - - 8.3536 1 221125_WJC_METTL3_EV_vs_WT_F07.21893.21893.4 1.15E-18 30/156 K.HMDGGQIDGQEITATAVLAPWPRPPPR.R "sp|Q15287|RNPS1_HUMAN,tr|H3BMM9|H3BMM9_HUMAN,tr|H3BV80|H3BV80_HUMAN,tr|H3BTC0|H3BTC0_HUMAN,tr|H3BPG5|H3BPG5_HUMAN" 5 2909.4606 2.92 106926 21893 4 2909.468023 728.3724 RNA-binding protein with serine-rich domain 1 OS=Homo sapiens OX=9606 GN=RNPS1 PE=1 SV=1 5.38 3475 - 685925 - - - 2.5355 - 4.751 0.741 - 577.9 1 2 0 0.0074 27 0 0 0 5.55E+07 1.90E+07 - - - 6.1612 0.9998 221125_WJC_METTL3_EV_vs_WT_F07.21896.21896.4 5.11E-07 10/150 K.TILDPLTLVQGNQNEDKHLVTDNPSK.L sp|Q5W0B1|OBI1_HUMAN 1 2888.488 1.19 106928 21896 4 2888.48915 723.1293 ORC ubiquitin ligase 1 OS=Homo sapiens OX=9606 GN=OBI1 PE=1 SV=1 4.66 3475.4 - 398939 - - - 0.4099 - 2.957 0.47 - 40.9 1 2 1 0.0012 26 0 0 0 4.97E+07 4.18E+07 - - - 3.6585 0.9581 221125_WJC_METTL3_EV_vs_WT_F07.21899.21899.4 0.0162 19/150 R.TGHILHPEYLQPLPSTPVSPIELDAK[136.11].K sp|Q96F45|ZN503_HUMAN 1 2859.5262 2.85 106931 21899 4 2860.516737 715.8888 Zinc finger protein 503 OS=Homo sapiens OX=9606 GN=ZNF503 PE=1 SV=1 5.26 3475.7 - 455336 - - - 346.4004 - 3.285 0.417 - 181.8 1 2 0 0.9905 26 0 0 0 1.14E+07 4.00E+06 - - - 2.9564 0.9999 221125_WJC_METTL3_EV_vs_WT_F07.21900.21900.4 0.000986 9/108 R.GLLQDDAHPTLVTYADHSK[136.11].L "sp|Q86U44|MTA70_HUMAN,tr|F5H6D8|F5H6D8_HUMAN,tr|H0YFV6|H0YFV6_HUMAN,tr|B4DTN4|B4DTN4_HUMAN" 4 2088.0367 0.1 106932 21900 4 2088.040643 523.0165 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 5.13 3475.9 - 307329 - - - 1.8726 - 2.18 0.477 - 75.5 1 2 0 0.0039 19 0 0 0 1.22E+06 1.21E+07 - - - 3.6404 0.9996 221125_WJC_METTL3_EV_vs_WT_F07.21901.21901.2 0.000205 16-Aug K.LLQDFFNGK[136.11].E "sp|P54652|HSP72_HUMAN,sp|P11142|HSP7C_HUMAN,sp|P17066|HSP76_HUMAN,tr|E9PNE6|E9PNE6_HUMAN,tr|A8K7Q2|A8K7Q2_HUMAN,tr|E9PKE3|E9PKE3_HUMAN,tr|E9PN89|E9PN89_HUMAN" 7 1088.5746 0.13 106933 21901 2 1088.574905 545.2946 Heat shock-related 70 kDa protein 2 OS=Homo sapiens OX=9606 GN=HSPA2 PE=1 SV=1 5.84 3476 - 221413 - - - 0.2848 - 1.534 0.404 - 133.2 1 2 0 0.0003 9 0 0 0 1.88E+06 1.46E+07 - - - 3.2627 0.9673 221125_WJC_METTL3_EV_vs_WT_F07.21908.21908.4 2.23E-06 11/126 Q.VATISANGDK[136.11]EIGNIISDAMK[136.11]K[136.11].V "sp|P10809|CH60_HUMAN,tr|A0A7I2V599|A0A7I2V599_HUMAN,tr|E7EXB4|E7EXB4_HUMAN,tr|A0A7I2YQ71|A0A7I2YQ71_HUMAN,tr|E7ESH4|E7ESH4_HUMAN,tr|A0A7I2V5M1|A0A7I2V5M1_HUMAN,tr|A0A7I2V5K3|A0A7I2V5K3_HUMAN,tr|A0A7I2V369|A0A7I2V369_HUMAN" 8 2298.2315 1.36 106938 21908 4 2298.232519 575.5652 "60 kDa heat shock protein, mitochondrial OS=Homo sapiens OX=9606 GN=HSPD1 PE=1 SV=2" 6.09 3476.8 - 585761 - - - 0.4229 - 2.255 0.45 - 54.1 1 1 1 0.001 22 0 0 0 1.34E+07 9.84E+06 - - - 3.4086 0.9595 221125_WJC_METTL3_EV_vs_WT_F07.21912.21912.4 0.00011 16/120 K.QISNLQQSISDAEQRGENALK.D sp|P04264|K2C1_HUMAN 1 2328.167 30.05 106940 21912 4 2328.163861 583.049 "Keratin, type II cytoskeletal 1 OS=Homo sapiens OX=9606 GN=KRT1 PE=1 SV=6" 4.68 3477.4 - 1.27E+06 - - - -1.3337 - 2.597 0.185 - 120.6 1 2 1 -0.0031 21 0 0 0 2.03E+07 6.76E+05 - - - 1.1509 0.9998 221125_WJC_METTL3_EV_vs_WT_F07.21917.21917.4 1.10E-05 18/144 R.SDKPIFTLNAHNDEISGLDLSSQIK.G "sp|Q13610|PWP1_HUMAN,tr|B4DJV5|B4DJV5_HUMAN" 2 2741.3872 2.05 106943 21917 4 2741.38143 686.3541 Periodic tryptophan protein 1 homolog OS=Homo sapiens OX=9606 GN=PWP1 PE=1 SV=1 4.66 3478 - 1.79E+06 - - - -2.1008 - 2.769 0.421 - 201.5 1 2 0 -0.0058 25 0 0 0 7.14E+07 3.49E+07 - - - 3.2128 0.9999 221125_WJC_METTL3_EV_vs_WT_F07.21921.21921.4 2.68E-05 18/144 R.SDK[136.11]PIFTLNAHNDEISGLDLSSQIK[136.11].G "sp|Q13610|PWP1_HUMAN,tr|B4DJV5|B4DJV5_HUMAN" 2 2757.4156 2.05 106945 21921 4 2757.408666 690.3612 Periodic tryptophan protein 1 homolog OS=Homo sapiens OX=9606 GN=PWP1 PE=1 SV=1 4.66 3478.5 - 1.15E+06 - - - -2.5107 - 3.105 0.517 - 164.1 1 2 0 -0.0069 25 0 0 0 7.05E+07 3.45E+07 - - - 4.0845 0.9999 221125_WJC_METTL3_EV_vs_WT_F07.21929.21929.4 5.56E-09 20/150 K.TILDPLTLVQGNQNEDK[136.11]HLVTDNPSK[136.11].L sp|Q5W0B1|OBI1_HUMAN 1 2904.5164 1.21 106950 21929 4 2904.512261 727.1364 ORC ubiquitin ligase 1 OS=Homo sapiens OX=9606 GN=OBI1 PE=1 SV=1 4.66 3479.5 - 1.60E+06 - - - -1.4133 - 3.404 0.507 - 196.8 1 2 1 -0.0041 26 0 0 0 5.12E+07 4.23E+07 - - - 4.0242 0.987 221125_WJC_METTL3_EV_vs_WT_F07.21930.21930.4 0.00143 20/126 Q.VATISANGDKEIGNIISDAMKK.V "sp|P10809|CH60_HUMAN,tr|A0A7I2V599|A0A7I2V599_HUMAN,tr|E7EXB4|E7EXB4_HUMAN,tr|A0A7I2YQ71|A0A7I2YQ71_HUMAN,tr|E7ESH4|E7ESH4_HUMAN,tr|A0A7I2V5M1|A0A7I2V5M1_HUMAN,tr|A0A7I2V5K3|A0A7I2V5K3_HUMAN,tr|A0A7I2V369|A0A7I2V369_HUMAN" 8 2274.1889 1.36 106951 21930 4 2274.187739 569.5545 "60 kDa heat shock protein, mitochondrial OS=Homo sapiens OX=9606 GN=HSPD1 PE=1 SV=2" 6.09 3479.6 - 408528 - - - -0.5312 - 3.29 0.517 - 213.1 1 1 1 -0.0012 22 0 0 0 1.34E+07 9.84E+06 - - - 4.1153 1 221125_WJC_METTL3_EV_vs_WT_F07.21943.21943.2 5.72E-10 17/40 K.QISNLQQSISDAEQRGENALK.D sp|P04264|K2C1_HUMAN 1 2328.167 999 106960 21943 2 2328.165936 1165.0908 "Keratin, type II cytoskeletal 1 OS=Homo sapiens OX=9606 GN=KRT1 PE=1 SV=6" 4.68 3481.3 - 837704 - - - -0.4424 - 3.643 0.66 - 461.1 1 2 1 -0.001 21 0 0 0 3.09E+07 0.00E+00 - - - 7.0939 1 221125_WJC_METTL3_EV_vs_WT_F07.21957.21957.4 2.40E-10 17/126 R.SQDHFHVFVGDLSPEITTEDIK.A "sp|P31483|TIA1_HUMAN,tr|F8W8I6|F8W8I6_HUMAN,tr|E5RGV5|E5RGV5_HUMAN" 3 2513.2074 1.85 106967 21957 4 2513.211667 629.3091 Nucleolysin TIA-1 isoform p40 OS=Homo sapiens OX=9606 GN=TIA1 PE=1 SV=3 4.42 3483.1 - 685060 - - - 1.6843 - 3.61 0.623 - 122 1 2 0 0.0042 22 0 0 0 2.54E+07 1.37E+07 - - - 5.0675 1 221125_WJC_METTL3_EV_vs_WT_F07.21959.21959.3 1.57E-09 15/96 R.SEIISTAPSSWVVPGPSPNEENNGK.S "sp|Q6W2J9|BCOR_HUMAN,tr|H7BZ37|H7BZ37_HUMAN,tr|H7C2V9|H7C2V9_HUMAN,tr|H7BYY2|H7BYY2_HUMAN,tr|H7C231|H7C231_HUMAN" 5 2595.2453 4 106969 21959 3 2595.243215 866.089 BCL-6 corepressor OS=Homo sapiens OX=9606 GN=BCOR PE=1 SV=1 4.25 3483.4 - 730965 - - - -0.7941 - 3.197 0.558 - 134.4 1 2 0 -0.0021 25 0 0 0 1.64E+07 4.10E+06 - - - 7.4344 0.9988 221125_WJC_METTL3_EV_vs_WT_F07.21963.21963.3 1.24E-06 18/52 Q.LDGIHLLDPDVVAR[166.11].F sp|Q86U44|MTA70_HUMAN 1 1541.8441 0.01 106971 21963 3 1541.843424 514.9553 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 4.41 3483.9 - 811006 - - - -0.4462 - 3.372 0.556 - 512.3 1 1 0 -0.0007 14 0 0 0 2.14E+05 2.93E+07 - - - 7.9689 1 221125_WJC_METTL3_EV_vs_WT_F07.21966.21966.4 1.24E-12 19/102 R.NVENEVSTLK[136.11]DQLEDLK[136.11]K[136.11].V "sp|Q13464|ROCK1_HUMAN,tr|A0A0U1RQV4|A0A0U1RQV4_HUMAN" 2 2125.1329 1.46 106974 21966 4 2125.133623 532.2905 Rho-associated protein kinase 1 OS=Homo sapiens OX=9606 GN=ROCK1 PE=1 SV=1 4.51 3484.3 - 375136 - - - 0.3501 - 3.488 0.66 - 252 1 2 1 0.0007 18 0 0 0 1.19E+07 8.17E+06 - - - 5.3984 1 221125_WJC_METTL3_EV_vs_WT_F07.21970.21970.4 1.86E-10 19/102 R.NVENEVSTLKDQLEDLKK.V "sp|Q13464|ROCK1_HUMAN,tr|A0A0U1RQV4|A0A0U1RQV4_HUMAN" 2 2101.0903 1.46 106976 21970 4 2101.091338 526.2798 Rho-associated protein kinase 1 OS=Homo sapiens OX=9606 GN=ROCK1 PE=1 SV=1 4.51 3484.8 - 806878 - - - 0.504 - 3.451 0.646 - 270.3 1 2 1 0.0011 18 0 0 0 1.19E+07 8.17E+06 - - - 5.2728 1 221125_WJC_METTL3_EV_vs_WT_F07.21978.21978.4 1.25E-08 13/180 M.PTGDFDSKPSWADQVEEEGEDDKC[160.03]VTSELLK.G "sp|O75821|EIF3G_HUMAN,tr|K7ER90|K7ER90_HUMAN,tr|K7EL20|K7EL20_HUMAN,tr|K7ENH0|K7ENH0_HUMAN,tr|K7ENA8|K7ENA8_HUMAN,tr|K7EL60|K7EL60_HUMAN" 6 3510.5621 1.11 106980 21978 4 3510.558802 878.6478 Eukaryotic translation initiation factor 3 subunit G OS=Homo sapiens OX=9606 GN=EIF3G PE=1 SV=2 3.93 3486 - 396940 - - - -0.9266 - 2.429 0.673 - 49.7 1 2 1 -0.0033 31 0 0 0 6.53E+07 5.87E+07 - - - 5.3526 1 221125_WJC_METTL3_EV_vs_WT_F07.21980.21980.4 2.04E-16 23/186 K.YGYNAGEATHHAVDSAVNVGVTAYNINNIGIK[136.11].A sp|Q8N0X7|SPART_HUMAN 1 3339.6364 1.1 106981 21980 4 3340.633954 835.9164 Spartin OS=Homo sapiens OX=9606 GN=SPART PE=1 SV=1 5.99 3486.2 - 6.21E+06 - - - 298.711 - 4.078 0.741 - 282.5 1 2 0 0.9976 32 0 0 0 1.41E+08 1.29E+08 - - - 5.8237 0.9894 221125_WJC_METTL3_EV_vs_WT_F07.21985.21985.3 0.000622 13/116 K.DLTVC[160.03]EPPKPQC[160.03]SLPQDPAIVQSSLGSSTS.S "sp|Q8ND56|LS14A_HUMAN,tr|A0A140TA76|A0A140TA76_HUMAN,tr|K7EMZ9|K7EMZ9_HUMAN" 3 3197.522 1.19 106983 21985 3 3197.520358 1066.848 Protein LSM14 homolog A OS=Homo sapiens OX=9606 GN=LSM14A PE=1 SV=3 4.03 3486.9 - 356369 - - - -0.5276 - 1.974 0.455 - 82.4 1 1 0 -0.0017 30 0 0 0 2.21E+07 1.86E+07 - - - 5.1769 1 221125_WJC_METTL3_EV_vs_WT_F07.21988.21988.4 0.000346 15/126 R.SQDHFHVFVGDLSPEITTEDIK[136.11].A "sp|P31483|TIA1_HUMAN,tr|F8W8I6|F8W8I6_HUMAN,tr|E5RGV5|E5RGV5_HUMAN" 3 2521.2216 1.93 106985 21988 4 2521.222494 631.3127 Nucleolysin TIA-1 isoform p40 OS=Homo sapiens OX=9606 GN=TIA1 PE=1 SV=3 4.42 3487.3 - 639183 - - - 0.3411 - 3.148 0.49 - 140.8 1 2 0 0.0009 22 0 0 0 2.48E+07 1.29E+07 - - - 3.8659 1 221125_WJC_METTL3_EV_vs_WT_F07.21998.21998.3 2.69E-16 28/124 R.GGGGSFGYSYGGGSGGGFSASSLGGGFGGGSR.G sp|P35527|K1C9_HUMAN 1 2704.1538 999 106990 21998 3 2704.151868 902.3919 "Keratin, type I cytoskeletal 9 OS=Homo sapiens OX=9606 GN=KRT9 PE=1 SV=3" 8.59 3488.6 - 1.33E+06 - - - -0.7274 - 4.759 0.725 - 433.2 1 2 0 -0.002 32 0 0 0 5.93E+08 0.00E+00 - - - 10.2116 0.7815 221125_WJC_METTL3_EV_vs_WT_F07.22000.22000.3 0.00282 Dec-72 K.R[166.11]R[166.11]AEQDSTTVAAFASSLVS.G "sp|Q86U44|MTA70_HUMAN,tr|F5H6D8|F5H6D8_HUMAN,tr|H0YFV6|H0YFV6_HUMAN,tr|B4DTN4|B4DTN4_HUMAN" 4 2015.0187 0 106991 22000 3 2015.020177 672.6802 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 6.07 3488.9 - 915380 - - - 0.7469 - 2.096 0.301 - 140.4 1 1 1 0.0015 19 0 0 0 2.56E+05 1.05E+08 - - - 3.7135 1 221125_WJC_METTL3_EV_vs_WT_F07.22003.22003.4 2.86E-12 30/180 M.PTGDFDSK[136.11]PSWADQVEEEGEDDK[136.11]C[160.03]VTSELLK[136.11].G "sp|O75821|EIF3G_HUMAN,tr|K7ER90|K7ER90_HUMAN,tr|K7EL20|K7EL20_HUMAN,tr|K7ENH0|K7ENH0_HUMAN,tr|K7ENA8|K7ENA8_HUMAN,tr|K7EL60|K7EL60_HUMAN" 6 3534.6047 1.11 106994 22003 4 3534.60713 884.6584 Eukaryotic translation initiation factor 3 subunit G OS=Homo sapiens OX=9606 GN=EIF3G PE=1 SV=2 3.93 3489.2 - 1.17E+06 - - - 0.7002 - 6.826 0.72 - 592.4 1 2 1 0.0025 31 0 0 0 6.53E+07 5.87E+07 - - - 6.076 1 221125_WJC_METTL3_EV_vs_WT_F07.22004.22004.2 3.75E-10 14/34 R.HDSEQDNSDNNTIFVQGL.G sp|P35637|FUS_HUMAN 1 2031.877 - 106995 22004 2 2031.878983 1016.9458 RNA-binding protein FUS OS=Homo sapiens OX=9606 GN=FUS PE=1 SV=1 3.84 3489.3 - 280015 - - - 0.9804 - 2.981 0.758 - 405.5 1 1 0 0.002 18 0 0 0 - - - - - 7.3243 1 221125_WJC_METTL3_EV_vs_WT_F07.22016.22016.2 5.54E-22 23/62 R.GGGGSFGYSYGGGSGGGFSASSLGGGFGGGSR.G sp|P35527|K1C9_HUMAN 1 2704.1538 999 107003 22016 2 2704.156341 1353.0842 "Keratin, type I cytoskeletal 9 OS=Homo sapiens OX=9606 GN=KRT9 PE=1 SV=3" 8.59 3490.9 - 233124 - - - 0.9267 - 4.449 0.849 - 895.6 1 2 0 0.0025 32 0 0 0 3.40E+07 0.00E+00 - - - 8.9807 1 221125_WJC_METTL3_EV_vs_WT_F07.22020.22020.3 6.33E-13 19/68 R.HDSEQDNSDNNTIFVQGL.G sp|P35637|FUS_HUMAN 1 2031.877 - 107005 22020 3 2031.878187 678.2996 RNA-binding protein FUS OS=Homo sapiens OX=9606 GN=FUS PE=1 SV=1 3.84 3491.4 - 1.62E+06 - - - 0.5886 - 3.284 0.761 - 441.8 1 1 0 0.0012 18 0 0 0 - - - - - 9.985 1 221125_WJC_METTL3_EV_vs_WT_F07.22028.22028.2 5.01E-11 20/38 K.GNPQGFNQGLDC[160.03]DVIVAEVR[166.11].S sp|Q86U44|MTA70_HUMAN 1 2197.0461 0 107011 22028 2 2198.045404 1099.5303 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 4.03 3492.4 - 3.01E+06 - - - 454.8234 - 3.75 0.666 - 1121.5 1 2 0 0.9993 20 0 0 0 6.01E+05 1.32E+08 - - - 6.8959 1 221125_WJC_METTL3_EV_vs_WT_F07.22030.22030.4 1.15E-06 25/132 K.EVTSHFQVTLNDIQLQMEQHNER[166.11].N sp|P40222|TXLNA_HUMAN 1 2805.338 0.91 107013 22030 4 2805.343329 702.3418 Alpha-taxilin OS=Homo sapiens OX=9606 GN=TXLNA PE=1 SV=3 4.8 3492.6 - 865492 - - - 1.9135 - 3.94 0.542 - 573.6 1 2 0 0.0054 23 0 0 0 1.94E+07 2.14E+07 - - - 4.3863 1 221125_WJC_METTL3_EV_vs_WT_F07.22031.22031.4 0.000512 23/132 K.EVTSHFQVTLNDIQLQMEQHNER.N sp|P40222|TXLNA_HUMAN 1 2795.3297 0.87 107014 22031 4 2795.333739 699.8397 Alpha-taxilin OS=Homo sapiens OX=9606 GN=TXLNA PE=1 SV=3 4.8 3492.8 - 830050 - - - 1.4481 - 3.56 0.494 - 407.5 1 2 0 0.004 23 0 0 0 1.90E+07 2.19E+07 - - - 3.936 1 221125_WJC_METTL3_EV_vs_WT_F07.22035.22035.3 1.61E-06 21/124 K.VGGTNLGAPGAFGQSPFSQPPAPPHQNTFPPR.S sp|Q96I24|FUBP3_HUMAN 1 3227.5901 2.62 107015 22035 3 3227.590372 1076.8706 Far upstream element-binding protein 3 OS=Homo sapiens OX=9606 GN=FUBP3 PE=1 SV=2 9.73 3493.3 - 652228 - - - 0.0905 - 3.5 0.615 - 219.6 1 2 0 0.0003 32 0 0 0 1.71E+08 6.54E+07 - - - 8.2787 1 221125_WJC_METTL3_EV_vs_WT_F07.22042.22042.4 1.94E-14 25/204 K.TKSTEEQLEEQQQQEEEVEEVEVEQVQVEADAQEK.A sp|Q8N5Z5|KCD17_HUMAN 1 4130.8775 35.45 107019 22042 4 4130.874003 1033.7267 BTB\POZ domain-containing protein KCTD17 OS=Homo sapiens OX=9606 GN=KCTD17 PE=1 SV=3 3.73 3494.2 - 638223 - - - -0.8495 - 4.349 0.694 - 293.3 1 2 1 -0.0035 35 0 0 0 5.69E+06 1.61E+05 - - - 5.7014 1 221125_WJC_METTL3_EV_vs_WT_F07.22045.22045.3 1.86E-07 17/60 R.HSDELTSLLGYFPNK[136.11]K[136.11].Q "sp|Q92878|RAD50_HUMAN,tr|E7EN38|E7EN38_HUMAN,tr|A0A494BZX5|A0A494BZX5_HUMAN,tr|H7C0P8|H7C0P8_HUMAN,tr|A0A494C1B7|A0A494C1B7_HUMAN,tr|A0A494C122|A0A494C122_HUMAN,tr|A0A494C0Y7|A0A494C0Y7_HUMAN,tr|A0A1W2PQ90|A0A1W2PQ90_HUMAN" 8 1863.9702 0.94 107020 22045 3 1863.971902 622.3307 DNA repair protein RAD50 OS=Homo sapiens OX=9606 GN=RAD50 PE=1 SV=1 6.75 3494.6 - 671297 - - - 0.9324 - 2.961 0.595 - 395.5 1 2 0 0.0017 16 0 0 0 2.91E+07 3.09E+07 - - - 7.9585 1 221125_WJC_METTL3_EV_vs_WT_F07.22051.22051.3 9.11E-10 22/60 R.HSDELTSLLGYFPNKK.Q "sp|Q92878|RAD50_HUMAN,tr|E7EN38|E7EN38_HUMAN,tr|A0A494BZX5|A0A494BZX5_HUMAN,tr|H7C0P8|H7C0P8_HUMAN,tr|A0A494C1B7|A0A494C1B7_HUMAN,tr|A0A494C122|A0A494C122_HUMAN,tr|A0A494C0Y7|A0A494C0Y7_HUMAN,tr|A0A1W2PQ90|A0A1W2PQ90_HUMAN" 8 1847.9418 0.94 107024 22051 3 1847.943716 616.9879 DNA repair protein RAD50 OS=Homo sapiens OX=9606 GN=RAD50 PE=1 SV=1 6.75 3495.5 - 1.01E+06 - - - 1.0563 - 3.16 0.638 - 706.4 1 2 0 0.002 16 0 0 0 2.91E+07 3.09E+07 - - - 8.6047 1 221125_WJC_METTL3_EV_vs_WT_F07.22054.22054.4 3.53E-06 21/156 K.FWEVISDEHGIDPTGTYHGDSDLQLER[166.11].L "sp|P04350|TBB4A_HUMAN,sp|P68371|TBB4B_HUMAN,tr|M0R2D3|M0R2D3_HUMAN,tr|M0QY85|M0QY85_HUMAN,tr|M0QZL7|M0QZL7_HUMAN,tr|M0R0X0|M0R0X0_HUMAN,tr|M0QYM7|M0QYM7_HUMAN,tr|M0R278|M0R278_HUMAN,tr|M0QY37|M0QY37_HUMAN,tr|M0QX14|M0QX14_HUMAN" 10 3125.4242 0.68 107027 22054 4 3125.426507 782.3633 Tubulin beta-4A chain OS=Homo sapiens OX=9606 GN=TUBB4A PE=1 SV=2 4.14 3495.9 - 746776 - - - 0.7404 - 3.641 0.53 - 203.4 1 2 0 0.0023 27 0 0 0 1.33E+07 1.95E+07 - - - 4.2428 1 221125_WJC_METTL3_EV_vs_WT_F07.22056.22056.4 1.61E-08 16/90 R.HSDELTSLLGYFPNK[136.11]K[136.11].Q "sp|Q92878|RAD50_HUMAN,tr|E7EN38|E7EN38_HUMAN,tr|A0A494BZX5|A0A494BZX5_HUMAN,tr|H7C0P8|H7C0P8_HUMAN,tr|A0A494C1B7|A0A494C1B7_HUMAN,tr|A0A494C122|A0A494C122_HUMAN,tr|A0A494C0Y7|A0A494C0Y7_HUMAN,tr|A0A1W2PQ90|A0A1W2PQ90_HUMAN" 8 1863.9702 0.91 107029 22056 4 1863.968961 466.9998 DNA repair protein RAD50 OS=Homo sapiens OX=9606 GN=RAD50 PE=1 SV=1 6.75 3496.1 - 184576 - - - -0.6454 - 2.74 0.638 - 250.1 1 2 0 -0.0012 16 0 0 0 5.31E+06 5.86E+06 - - - 5.1339 1 221125_WJC_METTL3_EV_vs_WT_F07.22063.22063.4 2.95E-07 15/90 R.HSDELTSLLGYFPNKK.Q "sp|Q92878|RAD50_HUMAN,tr|E7EN38|E7EN38_HUMAN,tr|A0A494BZX5|A0A494BZX5_HUMAN,tr|H7C0P8|H7C0P8_HUMAN,tr|A0A494C1B7|A0A494C1B7_HUMAN,tr|A0A494C122|A0A494C122_HUMAN,tr|A0A494C0Y7|A0A494C0Y7_HUMAN,tr|A0A1W2PQ90|A0A1W2PQ90_HUMAN" 8 1847.9418 0.89 107034 22063 4 1847.94515 462.9927 DNA repair protein RAD50 OS=Homo sapiens OX=9606 GN=RAD50 PE=1 SV=1 6.75 3497.1 - 325217 - - - 1.8323 - 2.642 0.627 - 220.9 1 2 0 0.0034 16 0 0 0 5.31E+06 5.99E+06 - - - 5.0247 1 221125_WJC_METTL3_EV_vs_WT_F07.22066.22066.4 1.17E-08 20/216 K.GDFFPPER[166.11]PQQLPHGLGGIGMGLGPGGQPIDANHLNK[136.11].G "sp|P52272|HNRPM_HUMAN,tr|M0R019|M0R019_HUMAN,tr|M0R0N3|M0R0N3_HUMAN,tr|A0A087X0X3|A0A087X0X3_HUMAN,tr|M0QZM1|M0QZM1_HUMAN" 5 3835.9336 0.001 107035 22066 4 3835.937657 959.9907 Heterogeneous nuclear ribonucleoprotein M OS=Homo sapiens OX=9606 GN=HNRNPM PE=1 SV=3 6 3497.5 - 218013 - - - 1.0662 - 4.165 0.59 - 151.3 1 2 0 0.0041 37 0 0 0 0.00E+00 1.26E+07 - - - 4.7785 0.9821 221125_WJC_METTL3_EV_vs_WT_F07.22067.22067.3 0.000593 Nov-56 N.QLDGIHLLDPDVVAR[166.11].F sp|Q86U44|MTA70_HUMAN 1 1669.9027 0.16 107036 22067 3 1669.90506 557.6415 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 4.41 3497.6 - 267905 - - - 1.4192 - 2.018 0.413 - 149.8 1 1 0 0.0024 15 0 0 0 2.60E+06 1.58E+07 - - - 4.9759 1 221125_WJC_METTL3_EV_vs_WT_F07.22068.22068.4 6.01E-09 22/162 R.DGGNPFAEPSELDNPFQDPAVIQHRPSR.Q sp|O14828|SCAM3_HUMAN 1 3089.4591 1.12 107037 22068 4 3089.466235 773.3721 Secretory carrier-associated membrane protein 3 OS=Homo sapiens OX=9606 GN=SCAMP3 PE=1 SV=3 4.43 3497.7 - 3.07E+06 - - - 2.3014 - 3.511 0.635 - 133.2 1 2 0 0.0071 28 0 0 0 2.02E+08 1.80E+08 - - - 5.141 0.999 221125_WJC_METTL3_EV_vs_WT_F07.22077.22077.4 0.00203 10/114 K.LAFAYLEDLHSEFDEQHGKK.V sp|O75396|SC22B_HUMAN 1 2376.1386 2.46 107042 22077 4 2376.138192 595.0419 Vesicle-trafficking protein SEC22b OS=Homo sapiens OX=9606 GN=SEC22B PE=1 SV=5 4.87 3498.9 - 194248 - - - -0.1826 - 1.914 0.298 - 61.9 1 2 0 -0.0004 20 0 0 0 3.13E+06 1.27E+06 - - - 2.0367 1 221125_WJC_METTL3_EV_vs_WT_F07.22086.22086.3 3.16E-07 14/72 K.VQDTSNTGLGEDIIHQLSK.S sp|Q8IWA0|WDR75_HUMAN 1 2054.028 1.73 107046 22086 3 2054.029714 685.6833 WD repeat-containing protein 75 OS=Homo sapiens OX=9606 GN=WDR75 PE=1 SV=1 4.54 3500 - 334389 - - - 0.8281 - 3.493 0.608 - 250 1 2 0 0.0017 19 0 0 0 1.53E+07 8.85E+06 - - - 8.391 0.9978 221125_WJC_METTL3_EV_vs_WT_F07.22088.22088.4 3.07E-05 13/126 K.DYYFDSYAHFGIHEEMLK[136.11]DEVR[166.11].T "sp|Q99873|ANM1_HUMAN,sp|Q9NR22|ANM8_HUMAN,tr|E9PQ98|E9PQ98_HUMAN,tr|E9PKG1|E9PKG1_HUMAN,tr|E9PMZ2|E9PMZ2_HUMAN,tr|E9PNR9|E9PNR9_HUMAN,tr|H0YDE4|H0YDE4_HUMAN,tr|E9PMW9|E9PMW9_HUMAN,tr|E9PIX6|E9PIX6_HUMAN" 9 2781.25 1.49 107047 22088 4 2781.264052 696.3198 Protein arginine N-methyltransferase 1 OS=Homo sapiens OX=9606 GN=PRMT1 PE=1 SV=3 4.57 3500.2 - 196904 - - - 5.0571 - 2.579 0.493 - 65.2 1 2 1 0.0141 22 0 0 0 8.41E+06 5.65E+06 - - - 3.8232 0.9895 221125_WJC_METTL3_EV_vs_WT_F07.22098.22098.4 1.25E-06 11/114 R.PLFPHVLC[160.03]HNC[160.03]AVEFNFGQK.E "sp|Q00839|HNRPU_HUMAN,tr|A0A1W2PQL0|A0A1W2PQL0_HUMAN,tr|A0A1W2PPL4|A0A1W2PPL4_HUMAN,tr|A0A1W2PQ74|A0A1W2PQ74_HUMAN,tr|Q5RI18|Q5RI18_HUMAN,tr|A0A1W2PP35|A0A1W2PP35_HUMAN,tr|A0A1W2PPS1|A0A1W2PPS1_HUMAN,tr|A0A1W2PRZ7|A0A1W2PRZ7_HUMAN,tr|A0A1W2PPH7|A0A1W2PPH7_HUMAN,tr|A0A1W2PP34|A0A1W2PP34_HUMAN,tr|A0A1X7SBS1|A0A1X7SBS1_HUMAN" 11 2413.146 1.32 107054 22098 4 2413.155537 604.2938 Heterogeneous nuclear ribonucleoprotein U OS=Homo sapiens OX=9606 GN=HNRNPU PE=1 SV=6 7.24 3501.6 - 351231 - - - 3.9616 - 2.907 0.609 - 91.2 1 1 0 0.0096 20 0 0 0 2.19E+07 1.66E+07 - - - 4.8808 0.9997 221125_WJC_METTL3_EV_vs_WT_F07.22099.22099.4 5.63E-06 14/102 K.ATHVVQSEVDK[136.11]YVDDIMK[136.11].E "sp|Q8IZ81|ELMD2_HUMAN,tr|D6RBS5|D6RBS5_HUMAN" 2 2092.0482 0.51 107055 22099 4 2092.052479 524.0193 ELMO domain-containing protein 2 OS=Homo sapiens OX=9606 GN=ELMOD2 PE=1 SV=1 4.66 3501.7 - 316499 - - - 2.0664 - 2.855 0.466 - 192.5 1 2 1 0.0043 18 0 0 0 6.29E+06 1.24E+07 - - - 3.6402 1 221125_WJC_METTL3_EV_vs_WT_F07.22103.22103.4 3.14E-13 21/126 K.DYYFDSYAHFGIHEEMLKDEVR.T "sp|Q99873|ANM1_HUMAN,sp|Q9NR22|ANM8_HUMAN,tr|E9PQ98|E9PQ98_HUMAN,tr|E9PKG1|E9PKG1_HUMAN,tr|E9PMZ2|E9PMZ2_HUMAN,tr|E9PNR9|E9PNR9_HUMAN,tr|H0YDE4|H0YDE4_HUMAN,tr|E9PMW9|E9PMW9_HUMAN,tr|E9PIX6|E9PIX6_HUMAN" 9 2763.2275 1.23 107057 22103 4 2763.23206 691.8142 Protein arginine N-methyltransferase 1 OS=Homo sapiens OX=9606 GN=PRMT1 PE=1 SV=3 4.57 3502.2 - 350453 - - - 1.6441 - 4.312 0.686 - 176.8 1 2 1 0.0045 22 0 0 0 8.55E+06 6.95E+06 - - - 5.6739 0.9303 221125_WJC_METTL3_EV_vs_WT_F07.22105.22105.3 7.04E-06 13/60 K.K[136.11]VSQEILELLNTTTAK[136.11].E "sp|Q86U44|MTA70_HUMAN,tr|H0YFV6|H0YFV6_HUMAN" 2 1803.0324 0.001 107059 22105 3 1804.022153 602.0181 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 6.14 3502.5 - 421223 - - - 548.9214 - 2.819 0.503 - 204 1 2 0 0.9897 16 0 0 0 0.00E+00 1.53E+06 - - - 6.533 0.9979 221125_WJC_METTL3_EV_vs_WT_F07.22112.22112.4 4.67E-12 18/114 R.PLFPHVLC[160.03]HNC[160.03]AVEFNFGQK[136.11].E "sp|Q00839|HNRPU_HUMAN,tr|A0A1W2PQL0|A0A1W2PQL0_HUMAN,tr|A0A1W2PPL4|A0A1W2PPL4_HUMAN,tr|A0A1W2PQ74|A0A1W2PQ74_HUMAN,tr|Q5RI18|Q5RI18_HUMAN,tr|A0A1W2PP35|A0A1W2PP35_HUMAN,tr|A0A1W2PPS1|A0A1W2PPS1_HUMAN,tr|A0A1W2PRZ7|A0A1W2PRZ7_HUMAN,tr|A0A1W2PPH7|A0A1W2PPH7_HUMAN,tr|A0A1W2PP34|A0A1W2PP34_HUMAN,tr|A0A1X7SBS1|A0A1X7SBS1_HUMAN" 11 2421.1602 1.3 107064 22112 4 2421.164477 606.2973 Heterogeneous nuclear ribonucleoprotein U OS=Homo sapiens OX=9606 GN=HNRNPU PE=1 SV=6 7.24 3503.4 - 428789 - - - 1.776 - 3.989 0.609 - 300.6 1 1 0 0.0043 20 0 0 0 2.09E+07 1.60E+07 - - - 4.9881 1 221125_WJC_METTL3_EV_vs_WT_F07.22114.22114.4 9.35E-06 11/114 R.TLYVHWTDAGQLTPALLHSR[166.11].C "sp|Q8IY67|RAVR1_HUMAN,tr|E9PAU2|E9PAU2_HUMAN,tr|A0A087WZ13|A0A087WZ13_HUMAN" 3 2288.1941 0.76 107066 22114 4 2288.198072 573.0558 Ribonucleoprotein PTB-binding 1 OS=Homo sapiens OX=9606 GN=RAVER1 PE=1 SV=1 6.61 3503.7 - 201012 - - - 1.7267 - 2.33 0.546 - 55.1 1 2 0 0.004 20 0 0 0 5.64E+06 7.42E+06 - - - 4.2601 0.9998 221125_WJC_METTL3_EV_vs_WT_F07.22118.22118.4 3.72E-06 12/126 K.YDSDGVWDPEK[136.11]WHASLYPASGR[166.11].S "sp|Q9NRA8|4ET_HUMAN,tr|B1AKL5|B1AKL5_HUMAN,tr|B1AKL4|B1AKL4_HUMAN" 3 2553.168 1.31 107067 22118 4 2553.173536 639.2993 Eukaryotic translation initiation factor 4E transporter OS=Homo sapiens OX=9606 GN=EIF4ENIF1 PE=1 SV=2 4.66 3504.3 - 248490 - - - 2.1793 - 2.524 0.523 - 89.2 1 2 1 0.0056 22 0 0 0 7.75E+06 5.93E+06 - - - 4.0796 0.9768 221125_WJC_METTL3_EV_vs_WT_F07.22119.22119.4 0.00653 9/114 R.TLYVHWTDAGQLTPALLHSR.C "sp|Q8IY67|RAVR1_HUMAN,tr|E9PAU2|E9PAU2_HUMAN,tr|A0A087WZ13|A0A087WZ13_HUMAN" 3 2278.1859 0.66 107068 22119 4 2278.198612 570.5537 Ribonucleoprotein PTB-binding 1 OS=Homo sapiens OX=9606 GN=RAVER1 PE=1 SV=1 6.61 3504.4 - 223398 - - - 5.6014 - 1.868 0.294 - 50.2 1 2 0 0.0128 20 0 0 0 4.78E+06 7.19E+06 - - - 1.9903 1 221125_WJC_METTL3_EV_vs_WT_F07.22123.22123.4 1.29E-17 26/198 K.LHGLQAILVHEASGTTAITATATGYQESHLSSAR.T sp|Q8TEM1|PO210_HUMAN 1 3490.7805 2.15 107070 22123 4 3490.796285 873.7024 Nuclear pore membrane glycoprotein 210 OS=Homo sapiens OX=9606 GN=NUP210 PE=1 SV=3 6.27 3504.9 - 251758 - - - 4.5334 - 5.85 0.706 - 362.1 1 2 0 0.0158 34 0 0 0 3.88E+06 1.81E+06 - - - 5.8934 1 221125_WJC_METTL3_EV_vs_WT_F07.22124.22124.3 9.72E-06 9/108 R.DGGNPFAEPSELDNPFQDPAVIQHRPSR.Q sp|O14828|SCAM3_HUMAN 1 3089.4591 2.16 107071 22124 3 3089.456167 1030.827 Secretory carrier-associated membrane protein 3 OS=Homo sapiens OX=9606 GN=SCAMP3 PE=1 SV=3 4.43 3505.1 - 161821 - - - -0.9574 - 2.171 0.539 - 36.6 1 2 0 -0.003 28 0 0 0 8.69E+06 4.02E+06 - - - 6.3319 1 221125_WJC_METTL3_EV_vs_WT_F07.22125.22125.4 7.26E-14 38/192 R.QGAPPAAGQGGALVELTPTPGGLALVSPYHTHR.A sp|Q9BV19|CA050_HUMAN 1 3219.6789 3.1 107072 22125 4 3219.693908 805.927 Uncharacterized protein C1orf50 OS=Homo sapiens OX=9606 GN=C1orf50 PE=1 SV=2 6.92 3505.2 - 520129 - - - 4.6629 - 6.707 0.698 - 834.7 1 2 0 0.015 33 0 0 0 6.45E+07 2.08E+07 - - - 5.8682 1 221125_WJC_METTL3_EV_vs_WT_F07.22130.22130.3 1.06E-12 16/132 F.SGGSFSRGSSGGGC[160.03]FGGSSGGYGGLGGFGGGSFR.G "sp|P13645|K1C10_HUMAN,tr|A0A1B0GVI3|A0A1B0GVI3_HUMAN" 2 3020.2856 999 107074 22130 3 3021.27585 1007.7691 "Keratin, type I cytoskeletal 10 OS=Homo sapiens OX=9606 GN=KRT10 PE=1 SV=6" 9.5 3506 - 391523 - - - 327.868 - 3.357 0.783 - 139.8 1 1 1 0.9903 34 0 0 0 2.97E+06 0.00E+00 - - - 9.7816 1 221125_WJC_METTL3_EV_vs_WT_F07.22149.22149.4 4.96E-09 17/198 K.LKPGEIDPNPETKPARPDPIDMDEDELEMLSEAR.A sp|Q99459|CDC5L_HUMAN 1 3846.8292 1.33 107086 22149 4 3846.839136 962.7146 Cell division cycle 5-like protein OS=Homo sapiens OX=9606 GN=CDC5L PE=1 SV=2 4.06 3508.4 - 325491 - - - 2.5868 - 2.724 0.575 - 104.5 1 2 0 0.01 34 0 0 0 4.09E+06 3.08E+06 - - - 4.5269 1 221125_WJC_METTL3_EV_vs_WT_F07.22158.22158.4 9.76E-12 44/192 R.QGAPPAAGQGGALVELTPTPGGLALVSPYHTHR[166.11].A sp|Q9BV19|CA050_HUMAN 1 3229.6872 3.08 107092 22158 4 3229.698387 808.4291 Uncharacterized protein C1orf50 OS=Homo sapiens OX=9606 GN=C1orf50 PE=1 SV=2 6.92 3509.6 - 1.02E+06 - - - 3.4746 - 7.413 0.678 - 1134.1 1 2 0 0.0112 33 0 0 0 6.41E+07 2.08E+07 - - - 5.7252 1 221125_WJC_METTL3_EV_vs_WT_F07.22164.22164.2 3.71E-07 14/22 K.SLNNQFASFIDK.V sp|P04264|K2C1_HUMAN 1 1382.683 12.63 107096 22164 2 1382.68712 692.3488 "Keratin, type II cytoskeletal 1 OS=Homo sapiens OX=9606 GN=KRT1 PE=1 SV=6" 5.55 3510.5 - 1.45E+06 - - - 2.958 - 2.855 0.599 - 655.1 1 2 0 0.0041 12 0 0 0 6.12E+07 4.85E+06 - - - 6.2242 0.9959 221125_WJC_METTL3_EV_vs_WT_F07.22174.22174.3 2.70E-05 16/64 L.GNQLDGIHLLDPDVVAR[166.11].F sp|Q86U44|MTA70_HUMAN 1 1840.9671 0.01 107104 22174 3 1840.971135 614.663 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 4.41 3511.7 - 480279 - - - 2.2021 - 3.249 0.514 - 287.6 1 1 0 0.0041 17 0 0 0 2.52E+06 3.45E+08 - - - 7.2463 1 221125_WJC_METTL3_EV_vs_WT_F07.22177.22177.3 8.25E-13 16/108 K.ASSISLDHNSVSSSSENSDEPLNLTFIK.K "sp|O60315|ZEB2_HUMAN,tr|U3KQ51|U3KQ51_HUMAN,tr|A0JP08|A0JP08_HUMAN,tr|A0A6Q8PH34|A0A6Q8PH34_HUMAN,tr|A0A1B0GW50|A0A1B0GW50_HUMAN,tr|A0A1B0GV02|A0A1B0GV02_HUMAN,tr|A0A1B0GVV8|A0A1B0GVV8_HUMAN" 7 2977.4153 6.46 107105 22177 3 2977.419174 993.479 Zinc finger E-box-binding homeobox 2 OS=Homo sapiens OX=9606 GN=ZEB2 PE=1 SV=1 4.31 3512.1 - 559584 - - - 1.3162 - 3.482 0.685 - 187.7 1 2 0 0.0039 28 0 0 0 1.43E+07 2.21E+06 - - - 9.0463 1 221125_WJC_METTL3_EV_vs_WT_F07.22184.22184.3 1.47E-13 17/104 K.SGTQDIQPGPLFNNNADGVATDITSTR[166.11].S "sp|Q7Z2W4|ZCCHV_HUMAN,tr|C9J6P4|C9J6P4_HUMAN,tr|A0A7P0T8C6|A0A7P0T8C6_HUMAN" 3 2798.3346 1.57 107109 22184 3 2798.325256 933.7855 Zinc finger CCCH-type antiviral protein 1 OS=Homo sapiens OX=9606 GN=ZC3HAV1 PE=1 SV=3 3.93 3512.9 - 431201 - - - -3.357 - 3.76 0.651 - 227.5 1 2 0 -0.0094 27 0 0 0 5.68E+07 3.61E+07 - - - 8.8424 1 221125_WJC_METTL3_EV_vs_WT_F07.22193.22193.3 2.47E-10 21/96 K.IDSIPHLNNSTPLVDPSVYGYGVQK.R sp|Q96I24|FUBP3_HUMAN 1 2712.3759 5.12 107115 22193 3 2712.377714 905.1326 Far upstream element-binding protein 3 OS=Homo sapiens OX=9606 GN=FUBP3 PE=1 SV=2 5.21 3514.1 - 1.20E+06 - - - 0.6703 - 3.524 0.63 - 367.5 1 2 0 0.0018 25 0 0 0 2.88E+07 5.63E+06 - - - 8.4612 1 221125_WJC_METTL3_EV_vs_WT_F07.22201.22201.3 1.51E-10 28/148 K.TFGGFASSSFGEQKPTGTFSSGGGSVASQGFGFSSPNK.T "sp|P35658|NU214_HUMAN,tr|A0A494C0Y1|A0A494C0Y1_HUMAN,tr|A0A0A0MSW3|A0A0A0MSW3_HUMAN,tr|B7ZAV2|B7ZAV2_HUMAN,tr|A0A494C1F2|A0A494C1F2_HUMAN,tr|H0Y837|H0Y837_HUMAN" 6 3690.6863 3.52 107121 22201 3 3690.680997 1231.236 Nuclear pore complex protein Nup214 OS=Homo sapiens OX=9606 GN=NUP214 PE=1 SV=2 8.26 3515.1 - 2.02E+06 - - - -1.4328 - 5.244 0.685 - 512.5 1 2 0 -0.0053 38 0 0 0 1.56E+08 4.45E+07 - - - 9.988 0.9999 221125_WJC_METTL3_EV_vs_WT_F07.22202.22202.4 7.16E-09 28/222 K.TFGGFASSSFGEQKPTGTFSSGGGSVASQGFGFSSPNK.T "sp|P35658|NU214_HUMAN,tr|A0A494C0Y1|A0A494C0Y1_HUMAN,tr|A0A0A0MSW3|A0A0A0MSW3_HUMAN,tr|B7ZAV2|B7ZAV2_HUMAN,tr|A0A494C1F2|A0A494C1F2_HUMAN,tr|H0Y837|H0Y837_HUMAN" 6 3690.6863 1.63 107122 22202 4 3690.681402 923.6788 Nuclear pore complex protein Nup214 OS=Homo sapiens OX=9606 GN=NUP214 PE=1 SV=2 8.26 3515.2 - 4.42E+06 - - - -1.3231 - 4.508 0.421 - 270.7 1 2 0 -0.0049 38 0 0 0 1.67E+08 1.02E+08 - - - 3.3281 1 221125_WJC_METTL3_EV_vs_WT_F07.22204.22204.4 8.60E-12 29/222 K.TFGGFASSSFGEQK[136.11]PTGTFSSGGGSVASQGFGFSSPNK[136.11].T "sp|P35658|NU214_HUMAN,tr|A0A494C0Y1|A0A494C0Y1_HUMAN,tr|A0A0A0MSW3|A0A0A0MSW3_HUMAN,tr|B7ZAV2|B7ZAV2_HUMAN,tr|A0A494C1F2|A0A494C1F2_HUMAN,tr|H0Y837|H0Y837_HUMAN" 6 3706.7147 1.63 107124 22204 4 3706.705903 927.6859 Nuclear pore complex protein Nup214 OS=Homo sapiens OX=9606 GN=NUP214 PE=1 SV=2 8.26 3515.5 - 2.43E+06 - - - -2.3692 - 4.801 0.614 - 335.6 1 2 0 -0.0088 38 0 0 0 1.67E+08 1.02E+08 - - - 5.0253 1 221125_WJC_METTL3_EV_vs_WT_F07.22212.22212.3 1.95E-13 29/148 K.TFGGFASSSFGEQK[136.11]PTGTFSSGGGSVASQGFGFSSPNK[136.11].T "sp|P35658|NU214_HUMAN,tr|A0A494C0Y1|A0A494C0Y1_HUMAN,tr|A0A0A0MSW3|A0A0A0MSW3_HUMAN,tr|B7ZAV2|B7ZAV2_HUMAN,tr|A0A494C1F2|A0A494C1F2_HUMAN,tr|H0Y837|H0Y837_HUMAN" 6 3706.7147 3.52 107129 22212 3 3706.698926 1236.5788 Nuclear pore complex protein Nup214 OS=Homo sapiens OX=9606 GN=NUP214 PE=1 SV=2 8.26 3516.5 - 2.69E+06 - - - -4.2515 - 5.029 0.668 - 601.2 1 2 0 -0.0158 38 0 0 0 1.56E+08 4.45E+07 - - - 9.6992 0.9999 221125_WJC_METTL3_EV_vs_WT_F07.22231.22231.3 6.33E-06 20/88 R.EQPEKEPELQQYVPQLQNNTILR.L sp|Q14152|EIF3A_HUMAN 1 2793.4297 1.31 107136 22231 3 2793.431784 932.1505 Eukaryotic translation initiation factor 3 subunit A OS=Homo sapiens OX=9606 GN=EIF3A PE=1 SV=1 4.49 3518.9 - 2.81E+06 - - - 0.7378 - 3.942 0.564 - 204 1 2 1 0.0021 23 0 0 0 1.23E+08 9.33E+07 - - - 8.0454 0.9994 221125_WJC_METTL3_EV_vs_WT_F07.22253.22253.3 0.00391 20/88 R.EQPEK[136.11]EPELQQYVPQLQNNTILR[166.11].L sp|Q14152|EIF3A_HUMAN 1 2811.4522 1.31 107141 22253 3 2811.447296 938.158 Eukaryotic translation initiation factor 3 subunit A OS=Homo sapiens OX=9606 GN=EIF3A PE=1 SV=1 4.49 3522.1 - 1.60E+06 - - - -1.7418 - 2.249 0.433 - 130.1 1 2 1 -0.0049 23 0 0 0 1.22E+08 9.32E+07 - - - 5.2675 0.9998 221125_WJC_METTL3_EV_vs_WT_F07.22259.22259.3 3.01E-12 22/72 R.IQEIIEQLDVTTSEYEK[136.11]EK[136.11].L "sp|P10809|CH60_HUMAN,tr|A0A7I2V2X6|A0A7I2V2X6_HUMAN,tr|A0A7I2YQK6|A0A7I2YQK6_HUMAN,tr|A0A7I2V599|A0A7I2V599_HUMAN" 4 2310.1813 0.69 107144 22259 3 2310.176974 771.0677 "60 kDa heat shock protein, mitochondrial OS=Homo sapiens OX=9606 GN=HSPD1 PE=1 SV=2" 4.14 3522.8 - 2.69E+06 - - - -1.8895 - 4.265 0.441 - 653.9 1 2 1 -0.0044 19 0 0 0 1.22E+08 1.78E+08 - - - 7.019 0.9999 221125_WJC_METTL3_EV_vs_WT_F07.22279.22279.3 1.90E-05 20/72 R.IQEIIEQLDVTTSEYEKEK.L "sp|P10809|CH60_HUMAN,tr|A0A7I2V2X6|A0A7I2V2X6_HUMAN,tr|A0A7I2YQK6|A0A7I2YQK6_HUMAN,tr|A0A7I2V599|A0A7I2V599_HUMAN" 4 2294.1529 0.7 107151 22279 3 2294.151639 765.7249 "60 kDa heat shock protein, mitochondrial OS=Homo sapiens OX=9606 GN=HSPD1 PE=1 SV=2" 4.14 3525.4 - 4.97E+06 - - - -0.5667 - 3.473 0.574 - 447.1 1 2 1 -0.0013 19 0 0 0 1.22E+08 1.75E+08 - - - 7.9979 0.9965 221125_WJC_METTL3_EV_vs_WT_F07.22280.22280.3 0.0018 20/76 K.HAASDVDLEIESLLNQQSTK[136.11].E "sp|Q86U44|MTA70_HUMAN,tr|F5H6D8|F5H6D8_HUMAN,tr|H0YFV6|H0YFV6_HUMAN,tr|B4DTN4|B4DTN4_HUMAN" 4 2205.1005 0.17 107152 22280 3 2206.093852 736.0408 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 4.31 3525.4 - 2.91E+06 - - - 450.4992 - 3.851 0.594 - 417.9 1 2 0 0.9934 20 0 0 0 2.24E+07 1.31E+08 - - - 8.1584 1 221125_WJC_METTL3_EV_vs_WT_F07.22284.22284.4 2.73E-10 39/252 K.VVGSAVGSGSITSNIVASNSLPPATIAPPKPASWADIASKPAK.Q sp|Q9Y5A9|YTHD2_HUMAN 1 4113.211 1.57 107154 22284 4 4113.208316 1029.31 YTH domain-containing family protein 2 OS=Homo sapiens OX=9606 GN=YTHDF2 PE=1 SV=2 9.7 3526 - 2.20E+06 - - - -0.655 - 4.765 0.65 - 402.4 1 2 0 -0.0027 43 0 0 0 2.93E+08 1.86E+08 - - - 5.3272 1 221125_WJC_METTL3_EV_vs_WT_F07.22288.22288.3 1.09E-11 27/144 R.EINDVAGEIDSVTSSGTAPSTTVSTAATTPGSAIDTR.E "sp|Q5SW79|CE170_HUMAN,tr|H0Y2V6|H0Y2V6_HUMAN,tr|E7EMW0|E7EMW0_HUMAN" 3 3578.7071 2.44 107156 22288 3 3578.706286 1193.9097 Centrosomal protein of 170 kDa OS=Homo sapiens OX=9606 GN=CEP170 PE=1 SV=1 3.77 3526.5 - 2.04E+06 - - - -0.2384 - 4.659 0.67 - 371 1 2 0 -0.0009 37 0 0 0 3.44E+07 1.41E+07 - - - 9.5498 0.9979 221125_WJC_METTL3_EV_vs_WT_F07.22314.22314.4 4.08E-06 14/114 K.HAASDVDLEIESLLNQQSTK[136.11].E "sp|Q86U44|MTA70_HUMAN,tr|F5H6D8|F5H6D8_HUMAN,tr|H0YFV6|H0YFV6_HUMAN,tr|B4DTN4|B4DTN4_HUMAN" 4 2205.1005 0.03 107168 22314 4 2206.099535 552.2824 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 4.31 3529.7 - 1.19E+06 - - - 453.0764 - 2.591 0.51 - 126 1 2 0 0.9991 20 0 0 0 1.70E+06 5.29E+07 - - - 3.7066 1 221125_WJC_METTL3_EV_vs_WT_F07.22317.22317.4 1.19E-08 20/114 K.KLAFAYLEDLHSEFDEQHGK.K sp|O75396|SC22B_HUMAN 1 2376.1386 25.85 107171 22317 4 2376.134176 595.0419 Vesicle-trafficking protein SEC22b OS=Homo sapiens OX=9606 GN=SEC22B PE=1 SV=5 4.87 3530.1 - 1.18E+06 - - - -1.8728 - 3.948 0.65 - 410.8 1 2 0 -0.0044 20 0 0 0 1.70E+08 6.57E+06 - - - 5.3415 0.9994 221125_WJC_METTL3_EV_vs_WT_F07.22321.22321.3 0.00313 6/124 K.ESESC[160.03]DC[160.03]LQGFQLTHSLGGGTGSGMGTLLISK.L "sp|Q9BVA1|TBB2B_HUMAN,sp|Q13885|TBB2A_HUMAN" 2 3326.5217 0.74 107173 22321 3 3326.521556 1109.8479 Tubulin beta-2B chain OS=Homo sapiens OX=9606 GN=TUBB2B PE=1 SV=1 4.65 3530.6 - 898131 - - - -0.0517 - 1.58 0.363 - 22.3 1 2 0 -0.0002 32 0 0 0 1.28E+08 1.73E+08 - - - 3.6394 1 221125_WJC_METTL3_EV_vs_WT_F07.22328.22328.3 6.44E-12 16/84 K.AAAIGIDLGTTYSC[160.03]VGVFQHGK[136.11].V "sp|P0DMV8|HS71A_HUMAN,sp|P0DMV9|HS71B_HUMAN,tr|V9GZ37|V9GZ37_HUMAN,tr|A0A0G2JIW1|A0A0G2JIW1_HUMAN" 4 2272.1402 0.01 107178 22328 3 2272.144319 758.3873 Heat shock 70 kDa protein 1A OS=Homo sapiens OX=9606 GN=HSPA1A PE=1 SV=1 6.78 3531.6 - 441901 - - - 1.8335 - 3.212 0.621 - 229.5 2 2 0 0.0042 22 0 0 0 1.38E+05 1.29E+07 - - - 8.0896 0.9993 221125_WJC_METTL3_EV_vs_WT_F07.22331.22331.3 0.136 7/124 K.ESESC[160.03]DC[160.03]LQGFQLTHSLGGGTGSGMGTLLISK[136.11].L "sp|Q9BVA1|TBB2B_HUMAN,sp|Q13885|TBB2A_HUMAN" 2 3334.5359 0.74 107179 22331 3 3334.535802 1112.5193 Tubulin beta-2B chain OS=Homo sapiens OX=9606 GN=TUBB2B PE=1 SV=1 4.65 3531.9 - 2.42E+06 - - - -0.0378 - 1.623 0.353 - 34.4 1 2 0 -0.0001 32 0 0 0 1.28E+08 1.73E+08 - - - 3.5897 1 221125_WJC_METTL3_EV_vs_WT_F07.22343.22343.4 5.76E-12 27/120 R.AAQLVDKDSTFLSTLEHHLSR.Y "sp|Q969V3|NCLN_HUMAN,tr|K7EMW4|K7EMW4_HUMAN,tr|K7ELZ9|K7ELZ9_HUMAN,tr|A0A0C4DGP7|A0A0C4DGP7_HUMAN" 4 2367.2183 1.06 107186 22343 4 2367.2201 592.8118 Nicalin OS=Homo sapiens OX=9606 GN=NCLN PE=1 SV=2 6 3533.4 - 965145 - - - 0.7718 - 5.081 0.635 - 613.7 1 2 1 0.0018 21 0 0 0 2.90E+07 2.72E+07 - - - 5.29 0.9999 221125_WJC_METTL3_EV_vs_WT_F07.22344.22344.4 1.96E-13 31/120 R.AAQLVDK[136.11]DSTFLSTLEHHLSR[166.11].Y "sp|Q969V3|NCLN_HUMAN,tr|K7EMW4|K7EMW4_HUMAN,tr|K7ELZ9|K7ELZ9_HUMAN,tr|A0A0C4DGP7|A0A0C4DGP7_HUMAN" 4 2385.2407 1.07 107187 22344 4 2385.241444 597.3175 Nicalin OS=Homo sapiens OX=9606 GN=NCLN PE=1 SV=2 6 3533.5 - 1.25E+06 - - - 0.2939 - 5.612 0.558 - 1009.6 1 2 1 0.0007 21 0 0 0 2.92E+07 2.74E+07 - - - 4.653 0.9997 221125_WJC_METTL3_EV_vs_WT_F07.22348.22348.3 7.79E-05 Dec-44 K.IEEIK[136.11]DFLLTAR[166.11].R "sp|P63173|RL38_HUMAN,tr|J3KT73|J3KT73_HUMAN,tr|J3QL01|J3QL01_HUMAN,tr|J3KSP2|J3KSP2_HUMAN" 4 1464.8307 1.67 107191 22348 3 1464.829435 489.2842 60S ribosomal protein L38 OS=Homo sapiens OX=9606 GN=RPL38 PE=1 SV=2 4.68 3534 - 289292 - - - -0.8636 - 2.067 0.455 - 200 1 2 1 -0.0013 12 0 0 0 1.28E+07 7.69E+06 - - - 5.6251 1 221125_WJC_METTL3_EV_vs_WT_F07.22355.22355.4 1.60E-11 26/126 K.VQALEEANNDLENKIQDWYDKK.G sp|P35527|K1C9_HUMAN 1 2662.2875 999 107194 22355 4 2662.288046 666.5791 "Keratin, type I cytoskeletal 9 OS=Homo sapiens OX=9606 GN=KRT9 PE=1 SV=3" 4.3 3534.9 - 5.16E+06 - - - 0.2145 - 5.019 0.675 - 558.7 1 2 1 0.0006 22 0 0 0 4.65E+08 0.00E+00 - - - 5.6289 1 221125_WJC_METTL3_EV_vs_WT_F07.22361.22361.4 2.34E-12 20/126 R.K[136.11]LFIGGLSFETTDDSLR[166.11]EHFEK[136.11].W "sp|P51991|ROA3_HUMAN,tr|A0A7I2V5D8|A0A7I2V5D8_HUMAN,tr|A0A7I2V2R3|A0A7I2V2R3_HUMAN,tr|A0A7I2V4J6|A0A7I2V4J6_HUMAN,tr|A0A7I2V4G0|A0A7I2V4G0_HUMAN,tr|A0A7I2V402|A0A7I2V402_HUMAN" 6 2594.3227 1.59 107198 22361 4 2594.323447 649.5879 Heterogeneous nuclear ribonucleoprotein A3 OS=Homo sapiens OX=9606 GN=HNRNPA3 PE=1 SV=2 4.9 3535.7 - 740955 - - - 0.2922 - 4.075 0.639 - 294.8 1 2 1 0.0008 22 0 0 0 3.19E+07 2.00E+07 - - - 5.2473 1 221125_WJC_METTL3_EV_vs_WT_F07.22364.22364.3 2.40E-12 28/84 K.VQALEEANNDLENKIQDWYDKK.G sp|P35527|K1C9_HUMAN 1 2662.2875 93.17 107199 22364 3 2662.288428 888.4364 "Keratin, type I cytoskeletal 9 OS=Homo sapiens OX=9606 GN=KRT9 PE=1 SV=3" 4.3 3536.1 - 1.48E+06 - - - 0.358 - 4.802 0.664 - 796.2 1 2 1 0.001 22 0 0 0 7.61E+07 8.17E+05 - - - 9.6626 0.9044 221125_WJC_METTL3_EV_vs_WT_F07.22367.22367.4 0.00438 15/138 K.QISNLQQSISDAEQRGENALKDAK.N sp|P04264|K2C1_HUMAN 1 2642.326 0.79 107202 22367 4 2643.321527 661.5888 "Keratin, type II cytoskeletal 1 OS=Homo sapiens OX=9606 GN=KRT1 PE=1 SV=6" 4.78 3536.5 - 350763 - - - 376.7669 - 2.745 0.386 - 128.1 1 2 2 0.9955 24 0 0 0 7.22E+06 9.13E+06 - - - 2.6341 1 221125_WJC_METTL3_EV_vs_WT_F07.22370.22370.4 3.53E-15 31/234 K.TAQALAQLAAQHSQSGSTTTSSWDMGSTTQSPSLVQYDLK.N "sp|Q14157|UBP2L_HUMAN,tr|F8W726|F8W726_HUMAN" 2 4181.9811 1.96 107203 22370 4 4181.983203 1046.5026 Ubiquitin-associated protein 2-like OS=Homo sapiens OX=9606 GN=UBAP2L PE=1 SV=2 5.18 3536.9 - 4.42E+06 - - - 0.4919 - 5.858 0.732 - 332.2 1 2 0 0.0021 40 0 0 0 2.91E+08 1.48E+08 - - - 6.1071 1 221125_WJC_METTL3_EV_vs_WT_F07.22371.22371.4 1.21E-09 34/150 K.EVLAGRPLFPHVLC[160.03]HNC[160.03]AVEFNFGQK.E "sp|Q00839|HNRPU_HUMAN,tr|A0A1W2PQL0|A0A1W2PQL0_HUMAN,tr|A0A1W2PPL4|A0A1W2PPL4_HUMAN,tr|A0A1W2PQ74|A0A1W2PQ74_HUMAN,tr|Q5RI18|Q5RI18_HUMAN,tr|A0A1W2PP35|A0A1W2PP35_HUMAN,tr|A0A1W2PPS1|A0A1W2PPS1_HUMAN,tr|A0A1W2PRZ7|A0A1W2PRZ7_HUMAN,tr|A0A1W2PPH7|A0A1W2PPH7_HUMAN,tr|A0A1W2PP34|A0A1W2PP34_HUMAN,tr|A0A1X7SBS1|A0A1X7SBS1_HUMAN" 11 3038.5007 1.09 107204 22371 4 3038.505753 760.6325 Heterogeneous nuclear ribonucleoprotein U OS=Homo sapiens OX=9606 GN=HNRNPU PE=1 SV=6 6.99 3536.9 - 3.01E+06 - - - 1.6508 - 5.483 0.676 - 869.3 1 2 0 0.005 26 0 0 0 1.83E+08 1.67E+08 - - - 5.6453 0.9999 221125_WJC_METTL3_EV_vs_WT_F07.22378.22378.4 4.46E-07 18/126 R.KLFIGGLSFETTDDSLREHFEK.W "sp|P51991|ROA3_HUMAN,tr|A0A7I2V5D8|A0A7I2V5D8_HUMAN,tr|A0A7I2V2R3|A0A7I2V2R3_HUMAN,tr|A0A7I2V4J6|A0A7I2V4J6_HUMAN,tr|A0A7I2V4G0|A0A7I2V4G0_HUMAN,tr|A0A7I2V402|A0A7I2V402_HUMAN" 6 2568.286 1.03 107206 22378 4 2568.287131 643.0788 Heterogeneous nuclear ribonucleoprotein A3 OS=Homo sapiens OX=9606 GN=HNRNPA3 PE=1 SV=2 4.9 3537.9 - 1.60E+06 - - - 0.433 - 3.299 0.595 - 232.9 1 2 1 0.0011 22 0 0 0 3.22E+07 3.14E+07 - - - 4.7951 1 221125_WJC_METTL3_EV_vs_WT_F07.22379.22379.3 1.24E-14 20/156 K.TAQALAQLAAQHSQSGSTTTSSWDMGSTTQSPSLVQYDLK.N "sp|Q14157|UBP2L_HUMAN,tr|F8W726|F8W726_HUMAN" 2 4181.9811 2.4 107207 22379 3 4181.987708 1395.001 Ubiquitin-associated protein 2-like OS=Homo sapiens OX=9606 GN=UBAP2L PE=1 SV=2 5.18 3538 - 1.12E+06 - - - 1.5691 - 4.776 0.727 - 232.8 1 2 0 0.0066 40 0 0 0 2.67E+07 1.11E+07 - - - 10.2408 1 221125_WJC_METTL3_EV_vs_WT_F07.22383.22383.3 6.30E-14 21/104 K.HTGPGILSMANAGPNTNGSQFFIC[160.03]TAK.T "sp|P62937|PPIA_HUMAN,tr|C9J5S7|C9J5S7_HUMAN,tr|A0A7I2V4V1|A0A7I2V4V1_HUMAN,tr|F8WE65|F8WE65_HUMAN" 4 2790.3218 1.23 107209 22383 3 2790.329716 931.1145 Peptidyl-prolyl cis-trans isomerase A OS=Homo sapiens OX=9606 GN=PPIA PE=1 SV=2 8.23 3538.6 - 451074 - - - 2.8481 - 4.654 0.715 - 509.4 1 2 0 0.0079 27 0 0 0 8.05E+06 6.55E+06 - - - 10.0471 1 221125_WJC_METTL3_EV_vs_WT_F07.22391.22391.4 1.75E-10 18/132 K.DTSNHFHVFVGDLSPEITTEDIK[136.11].S "sp|Q01085|TIAR_HUMAN,tr|C9JTN7|C9JTN7_HUMAN,tr|E7ETC0|E7ETC0_HUMAN,tr|H7BY49|H7BY49_HUMAN,tr|A6NKZ9|A6NKZ9_HUMAN,tr|E7ETJ9|E7ETJ9_HUMAN" 6 2608.2537 2.06 107211 22391 4 2608.254454 653.0707 Nucleolysin TIAR OS=Homo sapiens OX=9606 GN=TIAL1 PE=1 SV=1 4.42 3539.6 - 425335 - - - 0.3037 - 3.926 0.625 - 207.4 1 2 0 0.0008 23 0 0 0 2.81E+07 1.37E+07 - - - 5.1089 1 221125_WJC_METTL3_EV_vs_WT_F07.22395.22395.4 3.08E-11 24/132 K.DTSNHFHVFVGDLSPEITTEDIK.S "sp|Q01085|TIAR_HUMAN,tr|C9JTN7|C9JTN7_HUMAN,tr|E7ETC0|E7ETC0_HUMAN,tr|H7BY49|H7BY49_HUMAN,tr|A6NKZ9|A6NKZ9_HUMAN,tr|E7ETJ9|E7ETJ9_HUMAN" 6 2600.2395 2.06 107213 22395 4 2600.242603 651.0671 Nucleolysin TIAR OS=Homo sapiens OX=9606 GN=TIAL1 PE=1 SV=1 4.42 3540 - 950332 - - - 1.208 - 3.859 0.647 - 466 1 2 0 0.0031 23 0 0 0 2.81E+07 1.37E+07 - - - 5.2941 1 221125_WJC_METTL3_EV_vs_WT_F07.22397.22397.3 1.03E-16 30/120 K.TEQGGAHFSVSSLAEGSVTSVGSVNPAENFR.V sp|P13010|XRCC5_HUMAN 1 3120.4748 1.01 107215 22397 3 3120.475009 1041.1656 X-ray repair cross-complementing protein 5 OS=Homo sapiens OX=9606 GN=XRCC5 PE=1 SV=3 4.75 3540.3 - 705708 - - - 0.0558 - 5.386 0.745 - 717.6 1 2 0 0.0002 31 0 0 0 8.33E+07 8.26E+07 - - - 10.7198 0.9992 221125_WJC_METTL3_EV_vs_WT_F07.22402.22402.4 0.00452 10/108 R.GLLQDDAHPTLVTYADHSK[136.11].L "sp|Q86U44|MTA70_HUMAN,tr|F5H6D8|F5H6D8_HUMAN,tr|H0YFV6|H0YFV6_HUMAN,tr|B4DTN4|B4DTN4_HUMAN" 4 2088.0367 0.01 107218 22402 4 2088.030519 523.0165 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 5.13 3540.9 - 380846 - - - -2.976 - 1.981 0.371 - 70.7 1 2 0 -0.0062 19 0 0 0 7.91E+04 9.65E+06 - - - 2.6847 0.9998 221125_WJC_METTL3_EV_vs_WT_F07.22403.22403.4 1.71E-06 14/102 K.SKGLAPDLPEDLYHLIKK.A "sp|P62277|RS13_HUMAN,tr|J3KMX5|J3KMX5_HUMAN" 2 2036.1306 0.96 107219 22403 4 2036.133285 510.0399 40S ribosomal protein S13 OS=Homo sapiens OX=9606 GN=RPS13 PE=1 SV=2 6.47 3541.1 - 373517 - - - 1.3054 - 2.654 0.497 - 157.7 1 2 1 0.0027 18 0 0 0 7.30E+06 7.59E+06 - - - 3.8855 1 221125_WJC_METTL3_EV_vs_WT_F07.22411.22411.3 1.99E-13 23/88 K.DTSNHFHVFVGDLSPEITTEDIK.S "sp|Q01085|TIAR_HUMAN,tr|C9JTN7|C9JTN7_HUMAN,tr|E7ETC0|E7ETC0_HUMAN,tr|H7BY49|H7BY49_HUMAN,tr|A6NKZ9|A6NKZ9_HUMAN,tr|E7ETJ9|E7ETJ9_HUMAN" 6 2600.2395 1.57 107224 22411 3 2600.238534 867.7538 Nucleolysin TIAR OS=Homo sapiens OX=9606 GN=TIAL1 PE=1 SV=1 4.42 3542.1 - 406826 - - - -0.3569 - 4.431 0.718 - 681.1 1 2 0 -0.0009 23 0 0 0 5.35E+06 3.40E+06 - - - 10.037 0.9999 221125_WJC_METTL3_EV_vs_WT_F07.22412.22412.4 4.47E-09 22/96 K.AREGSEEDLDALEHMFR.Q sp|P31944|CASPE_HUMAN 1 2003.9007 999 107225 22412 4 2003.90505 501.9825 Caspase-14 OS=Homo sapiens OX=9606 GN=CASP14 PE=1 SV=2 4.35 3542.2 - 340716 - - - 2.1688 - 4.058 0.608 - 742.9 1 2 1 0.0043 17 0 0 0 6.71E+06 0.00E+00 - - - 5.0031 0.9999 221125_WJC_METTL3_EV_vs_WT_F07.22415.22415.4 2.95E-07 16/114 R.R[166.11]K[136.11]DGVFLYFEDNAGVIVNNK[136.11].G "sp|P62829|RL23_HUMAN,tr|J3KT29|J3KT29_HUMAN,tr|J3KTJ3|J3KTJ3_HUMAN" 3 2323.2171 0.95 107226 22415 4 2323.214796 581.8116 60S ribosomal protein L23 OS=Homo sapiens OX=9606 GN=RPL23 PE=1 SV=1 6.12 3542.6 - 610719 - - - -0.9922 - 2.894 0.524 - 193.3 1 2 1 -0.0023 20 0 0 0 1.32E+08 1.39E+08 - - - 4.1415 1 221125_WJC_METTL3_EV_vs_WT_F07.22417.22417.4 5.35E-14 27/264 R.APPGAPGPGPGSGAPGSQEEEEEPGLVEGDPGDGAIEDPELEAIK.A sp|Q86U42|PABP2_HUMAN 1 4304.9721 1.56 107227 22417 4 4304.980037 1077.2503 Polyadenylate-binding protein 2 OS=Homo sapiens OX=9606 GN=PABPN1 PE=1 SV=3 3.49 3542.8 - 1.31E+06 - - - 1.8481 - 3.706 0.742 - 192.5 1 2 0 0.008 45 0 0 0 4.64E+07 2.98E+07 - - - 6.0517 1 221125_WJC_METTL3_EV_vs_WT_F07.22418.22418.4 5.41E-11 28/180 K.TEQGGAHFSVSSLAEGSVTSVGSVNPAENFR[166.11].V sp|P13010|XRCC5_HUMAN 1 3130.4831 1.05 107228 22418 4 3130.487765 783.6281 X-ray repair cross-complementing protein 5 OS=Homo sapiens OX=9606 GN=XRCC5 PE=1 SV=3 4.75 3542.9 - 739224 - - - 1.4886 - 4.343 0.667 - 313.6 1 2 0 0.0047 31 0 0 0 2.16E+07 2.05E+07 - - - 5.4766 1 221125_WJC_METTL3_EV_vs_WT_F07.22426.22426.3 5.34E-10 18/64 K.AREGSEEDLDALEHMFR.Q sp|P31944|CASPE_HUMAN 1 2003.9007 999 107233 22426 3 2003.904405 668.9742 Caspase-14 OS=Homo sapiens OX=9606 GN=CASP14 PE=1 SV=2 4.35 3543.9 - 264737 - - - 1.8469 - 3.742 0.606 - 525.3 1 2 1 0.0037 17 0 0 0 3.06E+06 0.00E+00 - - - 8.629 1 221125_WJC_METTL3_EV_vs_WT_F07.22427.22427.3 2.08E-12 33/120 K.TEQGGAHFSVSSLAEGSVTSVGSVNPAENFR[166.11].V sp|P13010|XRCC5_HUMAN 1 3130.4831 1.02 107234 22427 3 3130.486669 1044.5016 X-ray repair cross-complementing protein 5 OS=Homo sapiens OX=9606 GN=XRCC5 PE=1 SV=3 4.75 3544.1 - 1.98E+06 - - - 1.1385 - 5.78 0.692 - 715.7 1 2 0 0.0036 31 0 0 0 8.41E+07 8.26E+07 - - - 10.2904 1 221125_WJC_METTL3_EV_vs_WT_F07.22428.22428.3 9.62E-12 20/76 R.R[166.11]K[136.11]DGVFLYFEDNAGVIVNNK[136.11].G "sp|P62829|RL23_HUMAN,tr|J3KT29|J3KT29_HUMAN,tr|J3KTJ3|J3KTJ3_HUMAN" 3 2323.2171 1.13 107235 22428 3 2323.211739 775.413 60S ribosomal protein L23 OS=Homo sapiens OX=9606 GN=RPL23 PE=1 SV=1 6.12 3544.2 - 473614 - - - -2.308 - 4.062 0.602 - 633.5 1 2 1 -0.0054 20 0 0 0 7.69E+07 6.82E+07 - - - 8.6507 0.9998 221125_WJC_METTL3_EV_vs_WT_F07.22430.22430.4 3.36E-05 16/102 K.SK[136.11]GLAPDLPEDLYHLIK[136.11]K[136.11].A "sp|P62277|RS13_HUMAN,tr|J3KMX5|J3KMX5_HUMAN" 2 2060.1732 0.96 107237 22430 4 2060.176381 516.0506 40S ribosomal protein S13 OS=Homo sapiens OX=9606 GN=RPS13 PE=1 SV=2 6.47 3544.5 - 290180 - - - 1.5309 - 3.074 0.49 - 211.5 1 2 1 0.0032 18 0 0 0 7.30E+06 7.59E+06 - - - 3.8748 0.9998 221125_WJC_METTL3_EV_vs_WT_F07.22435.22435.4 7.80E-11 20/114 R.RKDGVFLYFEDNAGVIVNNK.G "sp|P62829|RL23_HUMAN,tr|J3KT29|J3KT29_HUMAN,tr|J3KTJ3|J3KTJ3_HUMAN" 3 2297.1804 0.97 107240 22435 4 2297.187223 575.3024 60S ribosomal protein L23 OS=Homo sapiens OX=9606 GN=RPL23 PE=1 SV=1 6.12 3545.1 - 1.63E+06 - - - 2.9567 - 3.53 0.6 - 278.6 1 2 1 0.0068 20 0 0 0 1.33E+08 1.37E+08 - - - 4.8682 0.9999 221125_WJC_METTL3_EV_vs_WT_F07.22439.22439.4 6.37E-07 19/186 R.ELENGNLEVGVHIADVSHFIRPGNALDQESAR.R "sp|Q9Y2L1|RRP44_HUMAN,tr|F2Z2C0|F2Z2C0_HUMAN,tr|G3V1J5|G3V1J5_HUMAN" 3 3485.7288 1.93 107242 22439 4 3485.732992 872.4395 Exosome complex exonuclease RRP44 OS=Homo sapiens OX=9606 GN=DIS3 PE=1 SV=2 4.63 3545.6 - 690600 - - - 1.2147 - 3.798 0.453 - 180.6 1 2 0 0.0042 32 0 0 0 2.47E+07 1.28E+07 - - - 3.5707 0.8739 221125_WJC_METTL3_EV_vs_WT_F07.22441.22441.3 4.40E-08 25/104 K.DHTPSQELALTQSVGGDSSADR[166.11]LFPPQ.W "sp|Q86U44|MTA70_HUMAN,tr|H0YFV6|H0YFV6_HUMAN" 2 2862.3659 0 107244 22441 3 2863.371203 955.1293 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 4.22 3545.9 - 1.25E+06 - - - 351.1965 - 4.171 0.592 - 253.5 1 1 1 1.0053 27 0 0 0 1.45E+05 1.58E+08 - - - 8.1474 1 221125_WJC_METTL3_EV_vs_WT_F07.22447.22447.4 6.29E-09 23/222 K.GVTIPYRPKPSSSPVIFAGGQAYTIQGQYAIPQPDLTK.L tr|F8VRH0|F8VRH0_HUMAN 1 4045.1313 1.35 107248 22447 4 4045.138416 1012.2901 Poly(rC)-binding protein 2 (Fragment) OS=Homo sapiens OX=9606 GN=PCBP2 PE=1 SV=2 9.4 3546.7 - 414147 - - - 1.7584 - 4.106 0.614 - 120.5 1 2 0 0.0071 38 0 0 0 3.01E+07 2.23E+07 - - - 4.9802 1 221125_WJC_METTL3_EV_vs_WT_F07.22448.22448.3 9.34E-16 21/176 R.APPGAPGPGPGSGAPGSQEEEEEPGLVEGDPGDGAIEDPELEAIK.A sp|Q86U42|PABP2_HUMAN 1 4304.9721 2.18 107249 22448 3 4304.978682 1435.998 Polyadenylate-binding protein 2 OS=Homo sapiens OX=9606 GN=PABPN1 PE=1 SV=3 3.49 3546.8 - 327071 - - - 1.5333 - 4.266 0.791 - 162.5 1 2 0 0.0066 45 0 0 0 6.81E+06 3.12E+06 - - - 10.6945 1 221125_WJC_METTL3_EV_vs_WT_F07.22451.22451.4 1.32E-09 26/144 K.GDTNIKPILQVINIRPITTGNSPPR.Y "sp|P27694|RFA1_HUMAN,tr|I3L2M5|I3L2M5_HUMAN,tr|I3L524|I3L524_HUMAN" 3 2713.5239 1.32 107250 22451 4 2713.53049 679.3883 Replication protein A 70 kDa DNA-binding subunit OS=Homo sapiens OX=9606 GN=RPA1 PE=1 SV=2 10.84 3547.2 - 2.37E+06 - - - 2.4293 - 4.52 0.609 - 385.7 1 2 0 0.0066 25 0 0 0 5.15E+08 3.89E+08 - - - 5.0048 1 221125_WJC_METTL3_EV_vs_WT_F07.22452.22452.4 1.37E-09 27/144 K.GDTNIK[136.11]PILQVINIR[166.11]PITTGNSPPR[166.11].Y "sp|P27694|RFA1_HUMAN,tr|I3L2M5|I3L2M5_HUMAN,tr|I3L524|I3L524_HUMAN" 3 2741.5546 1.32 107251 22452 4 2741.561336 686.3959 Replication protein A 70 kDa DNA-binding subunit OS=Homo sapiens OX=9606 GN=RPA1 PE=1 SV=2 10.84 3547.4 - 2.00E+06 - - - 2.4431 - 3.586 0.584 - 402.2 1 2 0 0.0067 25 0 0 0 5.15E+08 3.89E+08 - - - 4.7135 0.9999 221125_WJC_METTL3_EV_vs_WT_F07.22453.22453.4 3.07E-09 23/162 K.VANDNAPEHALRPGFLSTFALATDQGSK.L sp|Q9UHA4|LTOR3_HUMAN 1 2926.4573 1.11 107252 22453 4 2926.468606 732.6216 Ragulator complex protein LAMTOR3 OS=Homo sapiens OX=9606 GN=LAMTOR3 PE=1 SV=1 5.38 3547.5 - 966858 - - - 3.8518 - 3.894 0.605 - 269.9 1 2 0 0.0113 28 0 0 0 2.21E+07 2.00E+07 - - - 4.9109 1 221125_WJC_METTL3_EV_vs_WT_F07.22454.22454.4 1.26E-07 18/222 K.GVTIPYR[166.11]PK[136.11]PSSSPVIFAGGQAYTIQGQYAIPQPDLTK[136.11].L tr|F8VRH0|F8VRH0_HUMAN 1 4071.168 1.35 107253 22454 4 4071.171061 1018.7993 Poly(rC)-binding protein 2 (Fragment) OS=Homo sapiens OX=9606 GN=PCBP2 PE=1 SV=2 9.4 3547.6 - 490335 - - - 0.7585 - 3.498 0.603 - 69.1 1 2 0 0.0031 38 0 0 0 3.01E+07 2.23E+07 - - - 4.8388 0.9919 221125_WJC_METTL3_EV_vs_WT_F07.22464.22464.4 0.00522 12/114 R.EFTMAEIEHFVDPSEKDHPK.F "sp|P41250|GARS_HUMAN,tr|H7C443|H7C443_HUMAN,tr|A0A6Q8PGI6|A0A6Q8PGI6_HUMAN,tr|A0A6Q8PGA8|A0A6Q8PGA8_HUMAN,tr|A0A6Q8PGW4|A0A6Q8PGW4_HUMAN,tr|A0A6Q8PGZ8|A0A6Q8PGZ8_HUMAN,tr|A0A6Q8PHH9|A0A6Q8PHH9_HUMAN,tr|A0A6Q8PHI7|A0A6Q8PHI7_HUMAN,tr|A0A6Q8PFZ6|A0A6Q8PFZ6_HUMAN" 9 2385.0947 1.29 107259 22464 4 2385.100641 597.281 Glycine--tRNA ligase OS=Homo sapiens OX=9606 GN=GARS1 PE=1 SV=3 4.63 3549 - 425791 - - - 2.4859 - 1.898 0.303 - 52.5 1 2 1 0.0059 20 0 0 0 1.10E+07 8.56E+06 - - - 2.0759 1 221125_WJC_METTL3_EV_vs_WT_F07.22468.22468.4 7.44E-09 29/186 R.ELENGNLEVGVHIADVSHFIR[166.11]PGNALDQESAR[166.11].R "sp|Q9Y2L1|RRP44_HUMAN,tr|F2Z2C0|F2Z2C0_HUMAN,tr|G3V1J5|G3V1J5_HUMAN" 3 3505.7453 2.26 107261 22468 4 3505.751626 877.4436 Exosome complex exonuclease RRP44 OS=Homo sapiens OX=9606 GN=DIS3 PE=1 SV=2 4.63 3549.5 - 844574 - - - 1.805 - 4.674 0.623 - 391.3 1 2 0 0.0063 32 0 0 0 2.53E+07 1.12E+07 - - - 5.1124 1 221125_WJC_METTL3_EV_vs_WT_F07.22472.22472.3 9.59E-15 18/92 R.NGPGFHNDIDSNSTIQEILIPASK.V sp|Q96I24|FUBP3_HUMAN 1 2566.2663 2.18 107264 22472 3 2566.275723 856.4294 Far upstream element-binding protein 3 OS=Homo sapiens OX=9606 GN=FUBP3 PE=1 SV=2 4.54 3550 - 375973 - - - 3.6539 - 3.751 0.736 - 177.3 1 2 0 0.0094 24 0 0 0 2.10E+08 9.63E+07 - - - 9.8136 1 221125_WJC_METTL3_EV_vs_WT_F07.22477.22477.4 1.88E-13 23/186 R.FSFLSKPVDENHQQDGDEDSLVSHFYTNPIAK.P "sp|P52948|NUP98_HUMAN,tr|A0A3B3ITD8|A0A3B3ITD8_HUMAN" 2 3663.7118 2.27 107267 22477 4 3663.722706 916.9352 Nuclear pore complex protein Nup98-Nup96 OS=Homo sapiens OX=9606 GN=NUP98 PE=1 SV=4 4.51 3550.7 - 537247 - - - 2.9847 - 4.089 0.702 - 190.2 1 1 0 0.0109 32 0 0 0 1.32E+07 5.81E+06 - - - 5.7584 0.9966 221125_WJC_METTL3_EV_vs_WT_F07.22479.22479.4 1.43E-05 12/186 R.FSFLSK[136.11]PVDENHQQDGDEDSLVSHFYTNPIAK[136.11].P "sp|P52948|NUP98_HUMAN,tr|A0A3B3ITD8|A0A3B3ITD8_HUMAN" 2 3679.7402 2.19 107269 22479 4 3679.736371 920.9423 Nuclear pore complex protein Nup98-Nup96 OS=Homo sapiens OX=9606 GN=NUP98 PE=1 SV=4 4.51 3550.9 - 387416 - - - -1.0327 - 2.024 0.534 - 37.9 1 1 0 -0.0038 32 0 0 0 1.28E+07 5.81E+06 - - - 4.0858 1 221125_WJC_METTL3_EV_vs_WT_F07.22485.22485.4 7.88E-17 19/192 R.K[136.11]EAESC[160.03]DC[160.03]LQGFQLTHSLGGGTGSGMGTLLISK[136.11].L "sp|P04350|TBB4A_HUMAN,sp|A6NNZ2|TBB8B_HUMAN,sp|P07437|TBB5_HUMAN,sp|P68371|TBB4B_HUMAN,sp|Q3ZCM7|TBB8_HUMAN,tr|Q5ST81|Q5ST81_HUMAN,tr|Q5JP53|Q5JP53_HUMAN,tr|M0R042|M0R042_HUMAN,tr|A0A075B736|A0A075B736_HUMAN,tr|Q5SQY0|Q5SQY0_HUMAN" 10 3454.6502 0.81 107273 22485 4 3454.653915 864.6698 Tubulin beta-4A chain OS=Homo sapiens OX=9606 GN=TUBB4A PE=1 SV=2 5.44 3551.7 - 710756 - - - 1.0823 - 4.235 0.772 - 143.5 1 2 0 0.0037 33 0 0 0 7.97E+06 9.89E+06 - - - 6.3775 0.9741 221125_WJC_METTL3_EV_vs_WT_F07.22486.22486.3 0.0653 15/60 R.DGLK[136.11]LMLLLEVISGER[166.11].L "sp|O43707|ACTN4_HUMAN,sp|P12814|ACTN1_HUMAN,tr|A0A804HK61|A0A804HK61_HUMAN,tr|A0A804HIN7|A0A804HIN7_HUMAN,tr|G3V5M4|G3V5M4_HUMAN,tr|A0A804HLF4|A0A804HLF4_HUMAN,tr|A0A804HIY0|A0A804HIY0_HUMAN,tr|A0A7I2V4Y4|A0A7I2V4Y4_HUMAN,tr|A0A804HII9|A0A804HII9_HUMAN,tr|A0A804HJQ9|A0A804HJQ9_HUMAN,tr|F5GXS2|F5GXS2_HUMAN,tr|A0A804HKE2|A0A804HKE2_HUMAN,tr|G3V2N5|G3V2N5_HUMAN,tr|A0A804HLD0|A0A804HLD0_HUMAN,tr|H7C144|H7C144_HUMAN" 15 1803.0295 0 107274 22486 3 1803.036296 602.0171 Alpha-actinin-4 OS=Homo sapiens OX=9606 GN=ACTN4 PE=1 SV=2 4.68 3551.8 - 1.33E+06 - - - 3.782 - 2.279 0.249 - 237.4 1 2 1 0.0068 16 0 0 0 3.14E+05 1.87E+08 - - - 3.4278 0.9997 221125_WJC_METTL3_EV_vs_WT_F07.22489.22489.4 6.66E-06 11/102 K.AK[136.11]QNDQVSFASLVEELK[136.11]K[136.11].V "sp|Q86UP2|KTN1_HUMAN,tr|G3V4Y7|G3V4Y7_HUMAN,tr|G3V5G2|G3V5G2_HUMAN,tr|H0YJZ8|H0YJZ8_HUMAN" 4 2057.1219 1.82 107277 22489 4 2057.127289 515.2878 Kinectin OS=Homo sapiens OX=9606 GN=KTN1 PE=1 SV=1 6.22 3552.2 - 208171 - - - 2.61 - 2.291 0.504 - 69.8 1 2 1 0.0054 18 0 0 0 9.06E+06 4.97E+06 - - - 3.8953 1 221125_WJC_METTL3_EV_vs_WT_F07.22494.22494.4 9.43E-14 24/192 R.KEAESC[160.03]DC[160.03]LQGFQLTHSLGGGTGSGMGTLLISK.L "sp|P04350|TBB4A_HUMAN,sp|A6NNZ2|TBB8B_HUMAN,sp|P07437|TBB5_HUMAN,sp|P68371|TBB4B_HUMAN,sp|Q3ZCM7|TBB8_HUMAN,tr|Q5ST81|Q5ST81_HUMAN,tr|Q5JP53|Q5JP53_HUMAN,tr|M0R042|M0R042_HUMAN,tr|A0A075B736|A0A075B736_HUMAN,tr|Q5SQY0|Q5SQY0_HUMAN" 10 3438.6218 0.82 107280 22494 4 3438.628691 860.6627 Tubulin beta-4A chain OS=Homo sapiens OX=9606 GN=TUBB4A PE=1 SV=2 5.44 3552.9 - 669607 - - - 2.011 - 4.434 0.724 - 225.6 1 2 0 0.0069 33 0 0 0 8.07E+06 9.89E+06 - - - 5.9726 1 221125_WJC_METTL3_EV_vs_WT_F07.22497.22497.4 6.52E-10 18/102 K.AKQNDQVSFASLVEELKK.V "sp|Q86UP2|KTN1_HUMAN,tr|G3V4Y7|G3V4Y7_HUMAN,tr|G3V5G2|G3V5G2_HUMAN,tr|H0YJZ8|H0YJZ8_HUMAN" 4 2033.0793 1.77 107283 22497 4 2033.080922 509.2771 Kinectin OS=Homo sapiens OX=9606 GN=KTN1 PE=1 SV=1 6.22 3553.3 - 302220 - - - 0.788 - 3.299 0.64 - 209.1 1 2 1 0.0016 18 0 0 0 9.06E+06 5.12E+06 - - - 5.205 1 221125_WJC_METTL3_EV_vs_WT_F07.22500.22500.3 3.42E-08 15/96 K.GDTNIKPILQVINIRPITTGNSPPR.Y "sp|P27694|RFA1_HUMAN,tr|I3L2M5|I3L2M5_HUMAN,tr|I3L524|I3L524_HUMAN" 3 2713.5239 1.5 107284 22500 3 2713.527995 905.5152 Replication protein A 70 kDa DNA-binding subunit OS=Homo sapiens OX=9606 GN=RPA1 PE=1 SV=2 10.84 3553.7 - 1.11E+06 - - - 1.5098 - 2.117 0.585 - 115 1 2 0 0.0041 25 0 0 0 5.69E+07 3.81E+07 - - - 6.7865 1 221125_WJC_METTL3_EV_vs_WT_F07.22506.22506.3 3.52E-07 15/96 K.GDTNIK[136.11]PILQVINIR[166.11]PITTGNSPPR[166.11].Y "sp|P27694|RFA1_HUMAN,tr|I3L2M5|I3L2M5_HUMAN,tr|I3L524|I3L524_HUMAN" 3 2741.5546 1.5 107288 22506 3 2741.556974 914.8588 Replication protein A 70 kDa DNA-binding subunit OS=Homo sapiens OX=9606 GN=RPA1 PE=1 SV=2 10.84 3554.5 - 1.01E+06 - - - 0.8521 - 2.076 0.63 - 110.8 1 2 0 0.0023 25 0 0 0 5.69E+07 3.80E+07 - - - 7.2437 1 221125_WJC_METTL3_EV_vs_WT_F07.22508.22508.4 6.10E-10 21/156 K.QFDNYGEEFTMHDTIGC[160.03]YLDIDKGHVK.F "sp|Q92499|DDX1_HUMAN,tr|A0A7I2V2M5|A0A7I2V2M5_HUMAN,tr|A0A087X2G1|A0A087X2G1_HUMAN,tr|A0A7I2V430|A0A7I2V430_HUMAN,tr|A0A7I2V421|A0A7I2V421_HUMAN,tr|A0A7I2V4F0|A0A7I2V4F0_HUMAN,tr|A0A7I2V5X8|A0A7I2V5X8_HUMAN,tr|A0A7I2V4J3|A0A7I2V4J3_HUMAN,tr|A0A087WZ71|A0A087WZ71_HUMAN,tr|A0A7I2YQ77|A0A7I2YQ77_HUMAN" 10 3231.4277 0.88 107290 22508 4 3231.43188 808.8642 ATP-dependent RNA helicase DDX1 OS=Homo sapiens OX=9606 GN=DDX1 PE=1 SV=2 4.51 3554.7 - 528208 - - - 1.2781 - 3.98 0.692 - 270.7 1 2 1 0.0041 27 0 0 0 6.50E+06 7.36E+06 - - - 5.6802 1 221125_WJC_METTL3_EV_vs_WT_F07.22514.22514.3 4.72E-12 22/92 R.NGPGFHNDIDSNSTIQEILIPASK[136.11].V sp|Q96I24|FUBP3_HUMAN 1 2574.2805 2.16 107294 22514 3 2574.284975 859.1008 Far upstream element-binding protein 3 OS=Homo sapiens OX=9606 GN=FUBP3 PE=1 SV=2 4.54 3555.5 - 748175 - - - 1.7205 - 3.792 0.611 - 272.7 1 2 0 0.0044 24 0 0 0 2.08E+08 9.63E+07 - - - 8.4466 1 221125_WJC_METTL3_EV_vs_WT_F07.22518.22518.3 1.49E-09 22/76 R.RKDGVFLYFEDNAGVIVNNK.G "sp|P62829|RL23_HUMAN,tr|J3KT29|J3KT29_HUMAN,tr|J3KTJ3|J3KTJ3_HUMAN" 3 2297.1804 1.12 107297 22518 3 2297.18481 766.7341 60S ribosomal protein L23 OS=Homo sapiens OX=9606 GN=RPL23 PE=1 SV=1 6.12 3556.1 - 1.18E+06 - - - 1.9062 - 4.624 0.64 - 739.5 1 2 1 0.0044 20 0 0 0 7.77E+07 6.96E+07 - - - 9.389 1 221125_WJC_METTL3_EV_vs_WT_F07.22520.22520.4 5.46E-09 32/252 K.VVGSAVGSGSITSNIVASNSLPPATIAPPKPASWADIASKPAK.Q sp|Q9Y5A9|YTHD2_HUMAN 1 4113.211 1.57 107298 22520 4 4113.215252 1029.31 YTH domain-containing family protein 2 OS=Homo sapiens OX=9606 GN=YTHDF2 PE=1 SV=2 9.7 3556.4 - 1.05E+06 - - - 1.0313 - 4.701 0.63 - 249 1 2 0 0.0042 43 0 0 0 2.94E+08 1.87E+08 - - - 5.1488 0.9936 221125_WJC_METTL3_EV_vs_WT_F07.22521.22521.2 0.00636 30-Nov R.DGLK[136.11]LMLLLEVISGER[166.11].L "sp|O43707|ACTN4_HUMAN,sp|P12814|ACTN1_HUMAN,tr|A0A804HK61|A0A804HK61_HUMAN,tr|A0A804HIN7|A0A804HIN7_HUMAN,tr|G3V5M4|G3V5M4_HUMAN,tr|A0A804HLF4|A0A804HLF4_HUMAN,tr|A0A804HIY0|A0A804HIY0_HUMAN,tr|A0A7I2V4Y4|A0A7I2V4Y4_HUMAN,tr|A0A804HII9|A0A804HII9_HUMAN,tr|A0A804HJQ9|A0A804HJQ9_HUMAN,tr|F5GXS2|F5GXS2_HUMAN,tr|A0A804HKE2|A0A804HKE2_HUMAN,tr|G3V2N5|G3V2N5_HUMAN,tr|A0A804HLD0|A0A804HLD0_HUMAN,tr|H7C144|H7C144_HUMAN" 15 1803.0295 0.001 107299 22521 2 1803.030717 902.522 Alpha-actinin-4 OS=Homo sapiens OX=9606 GN=ACTN4 PE=1 SV=2 4.68 3556.5 - 539355 - - - 0.6877 - 1.951 0.319 - 275.9 1 2 1 0.0012 16 0 0 0 0.00E+00 9.91E+06 - - - 3.0399 0.9999 221125_WJC_METTL3_EV_vs_WT_F07.22523.22523.4 2.24E-11 21/132 R.KNNFSDTGNFGFGIQEHIDLGIK.Y "sp|P62913|RL11_HUMAN,tr|Q5VVC8|Q5VVC8_HUMAN" 2 2550.2503 1.23 107301 22523 4 2550.258901 638.5699 60S ribosomal protein L11 OS=Homo sapiens OX=9606 GN=RPL11 PE=1 SV=2 5.38 3556.8 - 737347 - - - 3.3718 - 3.683 0.596 - 406.9 1 2 0 0.0086 23 0 0 0 3.10E+07 2.52E+07 - - - 4.8336 0.9974 221125_WJC_METTL3_EV_vs_WT_F07.22524.22524.2 0.157 14-Jun R.LTILELER[166.11].E sp|Q569K6|CC157_HUMAN 1 995.5891 0.01 107302 22524 2 995.589279 498.8018 Coiled-coil domain-containing protein 157 OS=Homo sapiens OX=9606 GN=CCDC157 PE=1 SV=3 4.53 3556.9 - 238189 - - - 0.2129 - 1.382 0.216 - 97.7 1 2 0 0.0002 8 0 0 0 3.16E+05 4.93E+07 - - - 1.6121 1 221125_WJC_METTL3_EV_vs_WT_F07.22529.22529.3 5.23E-16 30/104 K.QQNVDQAVATLQGEGLSVTGTVC[160.03]HVGK.A "sp|Q6PKH6|DR4L2_HUMAN,sp|Q9BTZ2|DHRS4_HUMAN,tr|F5GWZ1|F5GWZ1_HUMAN,tr|F6TD35|F6TD35_HUMAN,tr|E9PFL3|E9PFL3_HUMAN,tr|A0A087WXI8|A0A087WXI8_HUMAN" 6 2795.3872 1.28 107304 22529 3 2795.392948 932.803 Dehydrogenase\reductase SDR family member 4-like 2 OS=Homo sapiens OX=9606 GN=DHRS4L2 PE=2 SV=2 5.32 3557.6 - 531828 - - - 2.0541 - 4.7 0.713 - 990.7 1 2 0 0.0057 27 0 0 0 9.69E+07 7.55E+07 - - - 10.048 1 221125_WJC_METTL3_EV_vs_WT_F07.22530.22530.3 6.31E-09 11/104 R.KTQEQDEEVGLGTEEDPSLPALLTQPR.K sp|O95602|RPA1_HUMAN 1 2979.4673 0.74 107305 22530 3 2979.475187 994.163 DNA-directed RNA polymerase I subunit RPA1 OS=Homo sapiens OX=9606 GN=POLR1A PE=1 SV=2 4 3557.7 - 250838 - - - 2.6505 - 2.826 0.679 - 50 1 2 0 0.0079 27 0 0 0 3.38E+06 4.58E+06 - - - 8.498 1 221125_WJC_METTL3_EV_vs_WT_F07.22531.22531.4 2.17E-13 24/132 R.K[136.11]NNFSDTGNFGFGIQEHIDLGIK[136.11].Y "sp|P62913|RL11_HUMAN,tr|Q5VVC8|Q5VVC8_HUMAN" 2 2566.2787 1.26 107306 22531 4 2566.285819 642.577 60S ribosomal protein L11 OS=Homo sapiens OX=9606 GN=RPL11 PE=1 SV=2 5.38 3557.9 - 913399 - - - 2.7733 - 4.233 0.643 - 523.6 1 2 0 0.0071 23 0 0 0 3.25E+07 2.58E+07 - - - 5.2882 1 221125_WJC_METTL3_EV_vs_WT_F07.22532.22532.4 9.26E-16 34/222 K.GILGYTEHQVVSSDFNSDTHSSTFDAGAGIALNDHFVK.L "sp|P04406|G3P_HUMAN,tr|E7EUT5|E7EUT5_HUMAN" 2 4035.8875 0.96 107307 22532 4 4035.889257 1009.9792 Glyceraldehyde-3-phosphate dehydrogenase OS=Homo sapiens OX=9606 GN=GAPDH PE=1 SV=3 4.7 3558 - 878155 - - - 0.4344 - 5.451 0.681 - 421.9 1 2 0 0.0018 38 0 0 0 7.02E+08 7.35E+08 - - - 5.6474 1 221125_WJC_METTL3_EV_vs_WT_F07.22533.22533.3 1.30E-13 31/104 K.QQNVDQAVATLQGEGLSVTGTVC[160.03]HVGK[136.11].A "sp|Q6PKH6|DR4L2_HUMAN,sp|Q9BTZ2|DHRS4_HUMAN,tr|F5GWZ1|F5GWZ1_HUMAN,tr|F6TD35|F6TD35_HUMAN,tr|E9PFL3|E9PFL3_HUMAN,tr|A0A087WXI8|A0A087WXI8_HUMAN" 6 2803.4014 1.28 107308 22533 3 2803.403134 935.4744 Dehydrogenase\reductase SDR family member 4-like 2 OS=Homo sapiens OX=9606 GN=DHRS4L2 PE=2 SV=2 5.32 3558.1 - 395031 - - - 0.6164 - 4.934 0.69 - 961.9 1 2 0 0.0017 27 0 0 0 9.69E+07 7.55E+07 - - - 9.9045 1 221125_WJC_METTL3_EV_vs_WT_F07.22535.22535.3 6.30E-06 Oct-60 R.IINEPTAAAIAYGLDR[166.11].T "sp|P0DMV8|HS71A_HUMAN,sp|P0DMV9|HS71B_HUMAN,sp|P17066|HSP76_HUMAN,tr|A0A0G2JIW1|A0A0G2JIW1_HUMAN" 4 1696.9024 0.17 107310 22535 3 1696.903873 566.6414 Heat shock 70 kDa protein 1A OS=Homo sapiens OX=9606 GN=HSPA1A PE=1 SV=1 4.37 3558.4 - 205121 - - - 0.8946 - 2.557 0.499 - 116.1 1 2 0 0.0015 16 0 0 0 1.51E+06 9.05E+06 - - - 6.5119 1 221125_WJC_METTL3_EV_vs_WT_F07.22545.22545.4 1.76E-09 26/210 R.VSMK[136.11]PEFLHLTPGVQLEAGGDNLGQQYNSPQEVIGK[136.11].R sp|P11172|UMPS_HUMAN 1 3895.9749 1.3 107316 22545 4 3895.967316 975.001 Uridine 5'-monophosphate synthase OS=Homo sapiens OX=9606 GN=UMPS PE=1 SV=1 4.83 3559.7 - 1.21E+06 - - - -1.9566 - 5.095 0.593 - 346 1 2 0 -0.0076 36 0 0 0 3.60E+07 2.76E+07 - - - 4.8653 0.9993 221125_WJC_METTL3_EV_vs_WT_F07.22548.22548.4 0.0234 Sep-90 R.EKEHYC[160.03]LADLASLMDK.T "sp|Q92552|RT27_HUMAN,tr|E5RJ73|E5RJ73_HUMAN" 2 1921.8914 1.09 107319 22548 4 1921.895483 481.4801 "28S ribosomal protein S27, mitochondrial OS=Homo sapiens OX=9606 GN=MRPS27 PE=1 SV=3" 4.75 3560.1 - 162803 - - - 2.1323 - 1.738 0.43 - 67.4 1 2 1 0.0041 16 0 0 0 2.63E+06 2.42E+06 - - - 3.1623 1 221125_WJC_METTL3_EV_vs_WT_F07.22553.22553.2 2.96E-08 15/30 R.IINEPTAAAIAYGLDR[166.11].T "sp|P0DMV8|HS71A_HUMAN,sp|P0DMV9|HS71B_HUMAN,sp|P17066|HSP76_HUMAN,tr|A0A0G2JIW1|A0A0G2JIW1_HUMAN" 4 1696.9024 0.02 107322 22553 2 1696.903749 849.4585 Heat shock 70 kDa protein 1A OS=Homo sapiens OX=9606 GN=HSPA1A PE=1 SV=1 4.37 3560.8 - 616859 - - - 0.8215 - 3.169 0.581 - 612 1 2 0 0.0014 16 0 0 0 2.37E+05 1.21E+07 - - - 6.1676 0.9999 221125_WJC_METTL3_EV_vs_WT_F07.22555.22555.4 4.85E-10 23/114 R.TREGNDLYHEMIESGVINLK.D "sp|P06576|ATPB_HUMAN,tr|F8W079|F8W079_HUMAN,tr|H0YI37|H0YI37_HUMAN,tr|F8W0P7|F8W0P7_HUMAN,tr|H0YH81|H0YH81_HUMAN" 5 2317.1372 1.75 107323 22555 4 2317.141737 580.2916 "ATP synthase subunit beta, mitochondrial OS=Homo sapiens OX=9606 GN=ATP5F1B PE=1 SV=3" 4.83 3561 - 1.21E+06 - - - 1.9382 - 3.306 0.619 - 313.9 1 2 1 0.0045 20 0 0 0 3.81E+07 2.18E+07 - - - 5.0123 1 221125_WJC_METTL3_EV_vs_WT_F07.22557.22557.4 2.47E-09 33/156 K.QQNVDQAVATLQGEGLSVTGTVC[160.03]HVGK.A "sp|Q6PKH6|DR4L2_HUMAN,sp|Q9BTZ2|DHRS4_HUMAN,tr|F5GWZ1|F5GWZ1_HUMAN,tr|F6TD35|F6TD35_HUMAN,tr|E9PFL3|E9PFL3_HUMAN,tr|A0A087WXI8|A0A087WXI8_HUMAN" 6 2795.3872 0.76 107325 22557 4 2795.374881 699.8541 Dehydrogenase\reductase SDR family member 4-like 2 OS=Homo sapiens OX=9606 GN=DHRS4L2 PE=2 SV=2 5.32 3561.2 - 1.05E+06 - - - -4.409 - 5.592 0.637 - 957 1 2 0 -0.0123 27 0 0 0 9.41E+06 1.23E+07 - - - 5.3056 1 221125_WJC_METTL3_EV_vs_WT_F07.22558.22558.3 3.29E-10 15/88 R.K[136.11]QPAGNYSLSSVLPNAPDMAQFK[136.11].Q sp|Q9NP61|ARFG3_HUMAN 1 2478.2548 0.47 107326 22558 3 2478.251344 827.0922 ADP-ribosylation factor GTPase-activating protein 3 OS=Homo sapiens OX=9606 GN=ARFGAP3 PE=1 SV=1 8.5 3561.4 - 734641 - - - -1.3925 - 3.429 0.589 - 146.5 1 2 0 -0.0035 23 0 0 0 6.27E+06 1.32E+07 - - - 7.9966 1 221125_WJC_METTL3_EV_vs_WT_F07.22564.22564.3 4.69E-17 25/76 R.TREGNDLYHEMIESGVINLK.D "sp|P06576|ATPB_HUMAN,tr|F8W079|F8W079_HUMAN,tr|H0YI37|H0YI37_HUMAN,tr|F8W0P7|F8W0P7_HUMAN,tr|H0YH81|H0YH81_HUMAN" 5 2317.1372 2 107330 22564 3 2317.143878 773.3864 "ATP synthase subunit beta, mitochondrial OS=Homo sapiens OX=9606 GN=ATP5F1B PE=1 SV=3" 4.83 3562.2 - 865756 - - - 2.8622 - 4.483 0.729 - 732.6 1 2 1 0.0066 20 0 0 0 2.94E+07 1.47E+07 - - - 10.3055 0.9933 221125_WJC_METTL3_EV_vs_WT_F07.22566.22566.4 0.0369 Jun-90 R.EK[136.11]EHYC[160.03]LADLASLMDK[136.11].T "sp|Q92552|RT27_HUMAN,tr|E5RJ73|E5RJ73_HUMAN" 2 1937.9198 1.09 107332 22566 4 1937.918474 485.4872 "28S ribosomal protein S27, mitochondrial OS=Homo sapiens OX=9606 GN=MRPS27 PE=1 SV=3" 4.75 3562.4 - 210569 - - - -0.6765 - 1.45 0.285 - 42.4 1 2 1 -0.0013 16 0 0 0 2.63E+06 2.42E+06 - - - 1.8372 1 221125_WJC_METTL3_EV_vs_WT_F07.22571.22571.4 8.46E-11 18/138 K.DYALHWLVLGTHTSDEQNHLVVAR[166.11].V "sp|Q16576|RBBP7_HUMAN,tr|C9J7L0|C9J7L0_HUMAN,tr|E9PC52|E9PC52_HUMAN" 3 2783.4019 1.36 107335 22571 4 2783.41007 696.8577 Histone-binding protein RBBP7 OS=Homo sapiens OX=9606 GN=RBBP7 PE=1 SV=1 5.73 3563.1 - 494617 - - - 2.9417 - 3.777 0.61 - 208.2 1 2 0 0.0082 24 0 0 0 3.10E+07 2.28E+07 - - - 4.9597 1 221125_WJC_METTL3_EV_vs_WT_F07.22578.22578.4 1.16E-14 27/138 K.DYALHWLVLGTHTSDEQNHLVVAR.V "sp|Q16576|RBBP7_HUMAN,tr|C9J7L0|C9J7L0_HUMAN,tr|E9PC52|E9PC52_HUMAN" 3 2773.3936 1.36 107338 22578 4 2773.396219 694.3557 Histone-binding protein RBBP7 OS=Homo sapiens OX=9606 GN=RBBP7 PE=1 SV=1 5.73 3564 - 805806 - - - 0.94 - 5.295 0.71 - 504.1 1 2 0 0.0026 24 0 0 0 3.10E+07 2.28E+07 - - - 5.9401 0.9993 221125_WJC_METTL3_EV_vs_WT_F07.22579.22579.3 0.000255 14/84 K.DSGPLPTPPGVSLLGEPPK[136.11]DYR[166.11].L "tr|E9PAU2|E9PAU2_HUMAN,tr|A0A087WZ13|A0A087WZ13_HUMAN" 2 2309.2022 1.02 107339 22579 3 2309.204095 770.7414 Ribonucleoprotein PTB-binding 1 OS=Homo sapiens OX=9606 GN=RAVER1 PE=1 SV=1 4.56 3564.1 - 526988 - - - 0.8068 - 2.108 0.407 - 111.6 1 2 1 0.0019 22 0 0 0 1.57E+07 1.54E+07 - - - 4.8452 1 221125_WJC_METTL3_EV_vs_WT_F07.22580.22580.3 6.15E-10 22/116 K.TPSTMENDSSNLDPSQAPSLAQPLVFSNSK[136.11].Q "sp|Q14157|UBP2L_HUMAN,tr|F8W726|F8W726_HUMAN,tr|Q5VU77|Q5VU77_HUMAN" 3 3169.4965 2.55 107340 22580 3 3169.493092 1057.5061 Ubiquitin-associated protein 2-like OS=Homo sapiens OX=9606 GN=UBAP2L PE=1 SV=2 4.03 3564.3 - 828664 - - - -1.0715 - 3.622 0.73 - 298 1 2 0 -0.0034 30 0 0 0 1.04E+09 4.07E+08 - - - 9.6388 1 221125_WJC_METTL3_EV_vs_WT_F07.22592.22592.4 2.54E-08 26/126 K.NTTYDLIANIVHDGK[136.11]PSEGSYR[166.11].L "sp|Q53GS9|SNUT2_HUMAN,tr|B9A018|B9A018_HUMAN,tr|A0A087X1B2|A0A087X1B2_HUMAN" 3 2467.2098 0.95 107348 22592 4 2467.208999 617.8097 U4\U6.U5 tri-snRNP-associated protein 2 OS=Homo sapiens OX=9606 GN=USP39 PE=1 SV=2 5.38 3565.8 - 746320 - - - -0.3397 - 4.174 0.575 - 574.8 1 2 0 -0.0008 22 0 0 0 4.90E+07 5.15E+07 - - - 4.6981 0.983 221125_WJC_METTL3_EV_vs_WT_F07.22593.22593.2 3.55E-05 30-Sep R.R[166.11]AEQDSTTVAAFASSL.V "sp|Q86U44|MTA70_HUMAN,tr|F5H6D8|F5H6D8_HUMAN,tr|H0YFV6|H0YFV6_HUMAN,tr|B4DTN4|B4DTN4_HUMAN" 4 1662.8088 0.19 107349 22593 2 1662.806423 832.4117 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 4.37 3566 - 475444 - - - -1.459 - 1.961 0.468 - 123.3 1 1 0 -0.0024 16 0 0 0 2.37E+06 1.27E+07 - - - 4.1526 1 221125_WJC_METTL3_EV_vs_WT_F07.22597.22597.4 2.58E-15 25/204 R.SQPAFMQSSLSQPSVVLSGTAIHNFPTVQHQELAK.A "sp|Q9Y520|PRC2C_HUMAN,tr|E7EPN9|E7EPN9_HUMAN,tr|H7C5N8|H7C5N8_HUMAN,tr|A0A2R8Y7F4|A0A2R8Y7F4_HUMAN,tr|A0A2R8YET2|A0A2R8YET2_HUMAN" 5 3763.8992 2.05 107351 22597 4 3763.912022 941.9821 Protein PRRC2C OS=Homo sapiens OX=9606 GN=PRRC2C PE=1 SV=4 6.66 3566.5 - 526281 - - - 3.4079 - 4.802 0.675 - 277.8 1 2 0 0.0128 35 0 0 0 1.74E+08 8.49E+07 - - - 5.5628 1 221125_WJC_METTL3_EV_vs_WT_F07.22599.22599.3 2.02E-13 21/156 V.SSGYGGASGVGSGLGLGGGSSYSYGSGLGVGGGFSSSSGR.A "sp|P04259|K2C6B_HUMAN,sp|P02538|K2C6A_HUMAN" 2 3432.5454 999 107353 22599 3 3432.557437 1145.1891 "Keratin, type II cytoskeletal 6B OS=Homo sapiens OX=9606 GN=KRT6B PE=1 SV=5" 8.22 3566.8 - 435939 - - - 3.4968 - 4.085 0.724 - 169 1 1 0 0.012 40 0 0 0 1.05E+07 0.00E+00 - - - 9.8463 1 221125_WJC_METTL3_EV_vs_WT_F07.22603.22603.3 1.20E-05 23/108 K.KEESVVGSVTQLNQQIGQVNNAATLDLK.N "sp|Q2KHR3|QSER1_HUMAN,tr|A0A3B3IRW6|A0A3B3IRW6_HUMAN" 2 2982.5622 4.34 107355 22603 3 2982.561059 995.1947 Glutamine and serine-rich protein 1 OS=Homo sapiens OX=9606 GN=QSER1 PE=1 SV=3 4.68 3567.3 - 569618 - - - -0.3805 - 5.161 0.656 - 470.9 1 2 0 -0.0011 28 0 0 0 3.27E+07 7.54E+06 - - - 9.6291 1 221125_WJC_METTL3_EV_vs_WT_F07.22605.22605.4 1.71E-11 24/204 R.KFSAPGQLC[160.03]ISMTSNLGGSAPISAASATSLGHFTK.S "sp|Q9H4A3|WNK1_HUMAN,tr|F5GWT4|F5GWT4_HUMAN,tr|A0A6Q8PFM0|A0A6Q8PFM0_HUMAN" 3 3493.7334 2.12 107356 22605 4 3493.730737 874.4406 Serine\threonine-protein kinase WNK1 OS=Homo sapiens OX=9606 GN=WNK1 PE=1 SV=2 9.31 3567.5 - 631717 - - - -0.7551 - 3.845 0.606 - 272.8 1 2 0 -0.0026 35 0 0 0 4.86E+06 2.29E+06 - - - 4.8992 1 221125_WJC_METTL3_EV_vs_WT_F07.22610.22610.3 2.05E-09 26/80 K.EEYITSALESTEEKLHDAASK.L "sp|P52732|KIF11_HUMAN,tr|A0A7I2YQY4|A0A7I2YQY4_HUMAN,tr|A0A7I2V3A9|A0A7I2V3A9_HUMAN,tr|A0A7I2V3V3|A0A7I2V3V3_HUMAN" 4 2350.1176 10.47 107359 22610 3 2350.126364 784.3798 Kinesin-like protein KIF11 OS=Homo sapiens OX=9606 GN=KIF11 PE=1 SV=2 4.41 3568.1 - 2.37E+06 - - - 3.7224 - 4.879 0.605 - 1077.3 1 2 1 0.0087 21 0 0 0 1.00E+08 9.55E+06 - - - 9.0826 1 221125_WJC_METTL3_EV_vs_WT_F07.22613.22613.3 5.70E-16 28/116 K.TPSTMENDSSNLDPSQAPSLAQPLVFSNSK.Q "sp|Q14157|UBP2L_HUMAN,tr|F8W726|F8W726_HUMAN,tr|Q5VU77|Q5VU77_HUMAN" 3 3161.4823 2.55 107361 22613 3 3161.481248 1054.8347 Ubiquitin-associated protein 2-like OS=Homo sapiens OX=9606 GN=UBAP2L PE=1 SV=2 4.03 3568.5 - 2.24E+07 - - - -0.329 - 3.744 0.796 - 563.6 1 2 0 -0.001 30 0 0 0 1.04E+09 4.07E+08 - - - 10.4515 1 221125_WJC_METTL3_EV_vs_WT_F07.22617.22617.4 1.07E-08 28/204 R.SQPAFMQSSLSQPSVVLSGTAIHNFPTVQHQELAK[136.11].A "sp|Q9Y520|PRC2C_HUMAN,tr|E7EPN9|E7EPN9_HUMAN,tr|H7C5N8|H7C5N8_HUMAN,tr|A0A2R8Y7F4|A0A2R8Y7F4_HUMAN,tr|A0A2R8YET2|A0A2R8YET2_HUMAN" 5 3771.9134 2.05 107363 22617 4 3771.90953 943.9856 Protein PRRC2C OS=Homo sapiens OX=9606 GN=PRRC2C PE=1 SV=4 6.66 3568.9 - 1.51E+06 - - - -1.0247 - 4.357 0.565 - 329.1 1 2 0 -0.0039 35 0 0 0 1.74E+08 8.49E+07 - - - 4.579 1 221125_WJC_METTL3_EV_vs_WT_F07.22621.22621.4 1.05E-12 23/120 K.EEYITSALESTEEK[136.11]LHDAASK[136.11].L "sp|P52732|KIF11_HUMAN,tr|A0A7I2YQY4|A0A7I2YQY4_HUMAN,tr|A0A7I2V3A9|A0A7I2V3A9_HUMAN,tr|A0A7I2V3V3|A0A7I2V3V3_HUMAN" 4 2366.146 6.09 107365 22621 4 2366.142018 592.5438 Kinesin-like protein KIF11 OS=Homo sapiens OX=9606 GN=KIF11 PE=1 SV=2 4.41 3569.4 - 3.59E+06 - - - -1.6897 - 4.583 0.612 - 506.6 1 2 1 -0.004 21 0 0 0 3.63E+08 5.97E+07 - - - 5.0551 1 221125_WJC_METTL3_EV_vs_WT_F07.22634.22634.4 7.86E-06 24/126 K.NTTYDLIANIVHDGKPSEGSYR.L "sp|Q53GS9|SNUT2_HUMAN,tr|B9A018|B9A018_HUMAN,tr|A0A087X1B2|A0A087X1B2_HUMAN" 3 2449.1874 0.95 107372 22634 4 2449.187476 613.3041 U4\U6.U5 tri-snRNP-associated protein 2 OS=Homo sapiens OX=9606 GN=USP39 PE=1 SV=2 5.38 3571 - 3.24E+06 - - - 0.0445 - 3.159 0.469 - 198.4 1 2 0 0.0001 22 0 0 0 4.91E+07 5.15E+07 - - - 3.6845 1 221125_WJC_METTL3_EV_vs_WT_F07.22638.22638.4 7.48E-09 18/168 K.VIQNSTEC[160.03]TDAQQIWPGTWAPHIGNMHLK.Y "sp|Q8IWZ3|ANKH1_HUMAN,tr|A0A0A0MQZ8|A0A0A0MQZ8_HUMAN,tr|H0Y472|H0Y472_HUMAN,tr|H0Y7Y3|H0Y7Y3_HUMAN,tr|H0Y4P6|H0Y4P6_HUMAN,tr|H0Y785|H0Y785_HUMAN" 6 3331.5867 1.35 107375 22638 4 3331.588448 833.9039 Ankyrin repeat and KH domain-containing protein 1 OS=Homo sapiens OX=9606 GN=ANKHD1 PE=1 SV=1 5.99 3571.5 - 858018 - - - 0.5394 - 3.54 0.55 - 101.9 1 2 0 0.0018 29 0 0 0 6.65E+07 4.93E+07 - - - 4.4023 1 221125_WJC_METTL3_EV_vs_WT_F07.22644.22644.4 4.86E-10 22/174 K.SPQPPVEEEDEHFDDTVVC[160.03]LDTYNC[160.03]DLHFK.L "sp|Q00839|HNRPU_HUMAN,tr|Q5RI18|Q5RI18_HUMAN,tr|A0A1W2PP35|A0A1W2PP35_HUMAN,tr|A0A1W2PPS1|A0A1W2PPS1_HUMAN,tr|A0A1W2PRI6|A0A1W2PRI6_HUMAN" 5 3634.5504 1.07 107379 22644 4 3634.543521 909.6449 Heterogeneous nuclear ribonucleoprotein U OS=Homo sapiens OX=9606 GN=HNRNPU PE=1 SV=6 3.97 3572.2 - 1.23E+06 - - - -1.905 - 3.972 0.649 - 319.7 1 2 0 -0.0069 30 0 0 0 3.20E+07 2.98E+07 - - - 5.295 1 221125_WJC_METTL3_EV_vs_WT_F07.22645.22645.3 8.60E-07 26/144 R.GAGFNQNNGAGSENFGLGVVPVSASPSSVEVHPVLEK.L "sp|Q7Z739|YTHD3_HUMAN,tr|A0A087X0Q1|A0A087X0Q1_HUMAN,tr|A0A024R7W5|A0A024R7W5_HUMAN,tr|A0A087WY31|A0A087WY31_HUMAN" 4 3650.7965 1.64 107380 22645 3 3650.797402 1217.9394 YTH domain-containing family protein 3 OS=Homo sapiens OX=9606 GN=YTHDF3 PE=1 SV=1 4.75 3572.3 - 661574 - - - 0.246 - 4.461 0.736 - 312.6 1 2 0 0.0009 37 0 0 0 4.40E+07 2.68E+07 - - - 10.1857 1 221125_WJC_METTL3_EV_vs_WT_F07.22648.22648.4 2.66E-11 28/216 R.GAGFNQNNGAGSENFGLGVVPVSASPSSVEVHPVLEK.L "sp|Q7Z739|YTHD3_HUMAN,tr|A0A087X0Q1|A0A087X0Q1_HUMAN,tr|A0A024R7W5|A0A024R7W5_HUMAN,tr|A0A087WY31|A0A087WY31_HUMAN" 4 3650.7965 1.47 107381 22648 4 3650.794066 913.7064 YTH domain-containing family protein 3 OS=Homo sapiens OX=9606 GN=YTHDF3 PE=1 SV=1 4.75 3572.7 - 1.49E+06 - - - -0.6678 - 4.059 0.679 - 246.3 1 2 0 -0.0024 37 0 0 0 5.51E+07 3.74E+07 - - - 5.546 1 221125_WJC_METTL3_EV_vs_WT_F07.22651.22651.4 1.64E-07 28/132 K.HSSVYPTQEELEAVQNMVSHTER.A "sp|Q12906|ILF3_HUMAN,tr|K7EM82|K7EM82_HUMAN,tr|K7ER69|K7ER69_HUMAN,tr|K7ENK6|K7ENK6_HUMAN,tr|K7EJ09|K7EJ09_HUMAN,tr|K7ERM6|K7ERM6_HUMAN,tr|K7EKJ9|K7EKJ9_HUMAN" 7 2670.2344 1.18 107384 22651 4 2670.237477 668.5659 Interleukin enhancer-binding factor 3 OS=Homo sapiens OX=9606 GN=ILF3 PE=1 SV=3 4.87 3573.1 - 611315 - - - 1.1546 - 4.189 0.612 - 498.2 1 2 0 0.0031 23 0 0 0 3.15E+08 2.67E+08 - - - 5.0161 1 221125_WJC_METTL3_EV_vs_WT_F07.22654.22654.3 1.57E-14 31/112 K.AAQHQANQAAVAAQAAAAAATVMTQSTAK.A tr|A0A7P0T9I3|A0A7P0T9I3_HUMAN 1 2751.3722 1.27 107385 22654 3 2751.373922 918.1314 Muscleblind-like protein 2 OS=Homo sapiens OX=9606 GN=MBNL2 PE=1 SV=1 8.8 3573.5 - 812892 - - - 0.6168 - 6.091 0.699 - 1499.1 1 2 0 0.0017 29 0 0 0 2.82E+07 2.22E+07 - - - 10.4895 1 221125_WJC_METTL3_EV_vs_WT_F07.22658.22658.2 6.33E-11 16/58 K.TPSTMENDSSNLDPSQAPSLAQPLVFSNSK.Q "sp|Q14157|UBP2L_HUMAN,tr|F8W726|F8W726_HUMAN,tr|Q5VU77|Q5VU77_HUMAN" 3 3161.4823 7.13 107389 22658 2 3161.48626 1581.7484 Ubiquitin-associated protein 2-like OS=Homo sapiens OX=9606 GN=UBAP2L PE=1 SV=2 4.03 3574 - 434678 - - - 1.2564 - 3.308 0.739 - 344 1 2 0 0.004 30 0 0 0 1.71E+07 2.40E+06 - - - 7.4393 1 221125_WJC_METTL3_EV_vs_WT_F07.22665.22665.4 6.29E-15 32/168 K.AAQHQANQAAVAAQAAAAAATVMTQSTAK.A tr|A0A7P0T9I3|A0A7P0T9I3_HUMAN 1 2751.3722 1.32 107391 22665 4 2751.378762 688.8503 Muscleblind-like protein 2 OS=Homo sapiens OX=9606 GN=MBNL2 PE=1 SV=1 8.8 3575 - 455319 - - - 2.3759 - 5.676 0.616 - 990.5 1 2 0 0.0065 29 0 0 0 1.20E+07 9.08E+06 - - - 5.1209 0.9993 221125_WJC_METTL3_EV_vs_WT_F07.22670.22670.4 0.017 8/108 R.GLLQDDAHPTLVTYADHSK[136.11].L "sp|Q86U44|MTA70_HUMAN,tr|F5H6D8|F5H6D8_HUMAN,tr|H0YFV6|H0YFV6_HUMAN,tr|B4DTN4|B4DTN4_HUMAN" 4 2088.0367 0.01 107393 22670 4 2088.032547 523.0165 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 5.13 3575.7 - 280638 - - - -2.0048 - 2.039 0.337 - 60.3 1 2 0 -0.0042 19 0 0 0 5.83E+04 8.09E+06 - - - 2.3991 0.9998 221125_WJC_METTL3_EV_vs_WT_F07.22672.22672.4 2.88E-06 17/126 R.SENR[166.11]GELGIFVQEIQEGSVAHR[166.11].D "sp|O75970|MPDZ_HUMAN,tr|F5H1U9|F5H1U9_HUMAN" 2 2474.2417 1.63 107394 22672 4 2474.240181 619.5677 Multiple PDZ domain protein OS=Homo sapiens OX=9606 GN=MPDZ PE=1 SV=2 4.9 3576 - 665331 - - - -0.6099 - 3.159 0.462 - 223.9 1 2 1 -0.0015 22 0 0 0 2.55E+07 1.56E+07 - - - 3.6232 0.9999 221125_WJC_METTL3_EV_vs_WT_F07.22674.22674.4 1.93E-09 23/126 R.SENRGELGIFVQEIQEGSVAHR.D "sp|O75970|MPDZ_HUMAN,tr|F5H1U9|F5H1U9_HUMAN" 2 2454.2252 1.75 107396 22674 4 2454.229181 614.5636 Multiple PDZ domain protein OS=Homo sapiens OX=9606 GN=MPDZ PE=1 SV=2 4.9 3576.2 - 1.07E+06 - - - 1.6425 - 4.772 0.581 - 411.9 1 2 1 0.004 22 0 0 0 2.51E+07 1.43E+07 - - - 4.7932 0.9884 221125_WJC_METTL3_EV_vs_WT_F07.22678.22678.3 1.54E-05 Jul-92 L.QTSSTGNEAGGVNSNQFEELLQER.D "sp|Q15643|TRIPB_HUMAN,tr|H0YJ97|H0YJ97_HUMAN" 2 2594.1845 1.97 107398 22678 3 2594.185007 865.7354 Thyroid receptor-interacting protein 11 OS=Homo sapiens OX=9606 GN=TRIP11 PE=1 SV=3 4.09 3576.7 - 257924 - - - 0.2082 - 2.066 0.436 - 46.2 1 1 0 0.0005 24 0 0 0 2.74E+06 1.39E+06 - - - 5.0861 1 221125_WJC_METTL3_EV_vs_WT_F07.22679.22679.3 4.21E-08 20/120 K.VGGTNPNGGSFEEVLSSTAHASAQSLAGGSR.R "sp|Q16890|TPD53_HUMAN,tr|E9PPQ1|E9PPQ1_HUMAN,tr|J3KNE7|J3KNE7_HUMAN" 3 2944.3911 2.85 107399 22679 3 2944.402361 982.471 Tumor protein D53 OS=Homo sapiens OX=9606 GN=TPD52L1 PE=1 SV=1 5.4 3576.9 - 322925 - - - 3.8229 - 4.041 0.659 - 277.8 1 2 0 0.0113 31 0 0 0 1.74E+07 6.13E+06 - - - 9.0969 1 221125_WJC_METTL3_EV_vs_WT_F07.22684.22684.4 1.52E-12 35/150 R.HNLITEMVALNPDFKPPADYKPPATR.V "sp|Q15637|SF01_HUMAN,tr|A0A7P0T9U7|A0A7P0T9U7_HUMAN" 2 2934.5062 1.2 107400 22684 4 2934.512932 734.6338 Splicing factor 1 OS=Homo sapiens OX=9606 GN=SF1 PE=1 SV=4 6.75 3577.6 - 2.65E+06 - - - 2.2944 - 5.164 0.682 - 1026.2 1 2 0 0.0067 26 0 0 0 1.85E+08 1.53E+08 - - - 5.6781 1 221125_WJC_METTL3_EV_vs_WT_F07.22686.22686.3 0.000742 33/88 K.HSSVYPTQEELEAVQNMVSHTER.A "sp|Q12906|ILF3_HUMAN,tr|K7EM82|K7EM82_HUMAN,tr|K7ER69|K7ER69_HUMAN,tr|K7ENK6|K7ENK6_HUMAN,tr|K7EJ09|K7EJ09_HUMAN,tr|K7ERM6|K7ERM6_HUMAN,tr|K7EKJ9|K7EKJ9_HUMAN" 7 2670.2344 0.57 107402 22686 3 2670.238953 891.0854 Interleukin enhancer-binding factor 3 OS=Homo sapiens OX=9606 GN=ILF3 PE=1 SV=3 4.87 3577.9 - 1.18E+06 - - - 1.7073 - 5.636 0.636 - 1509.8 1 2 0 0.0046 23 0 0 0 9.06E+07 1.59E+08 - - - 9.6861 1 221125_WJC_METTL3_EV_vs_WT_F07.22691.22691.3 1.44E-12 26/144 R.GAGFNQNNGAGSENFGLGVVPVSASPSSVEVHPVLEK[136.11].L "sp|Q7Z739|YTHD3_HUMAN,tr|A0A087X0Q1|A0A087X0Q1_HUMAN,tr|A0A024R7W5|A0A024R7W5_HUMAN,tr|A0A087WY31|A0A087WY31_HUMAN" 4 3658.8107 1.64 107404 22691 3 3658.809424 1220.6108 YTH domain-containing family protein 3 OS=Homo sapiens OX=9606 GN=YTHDF3 PE=1 SV=1 4.75 3578.6 - 731978 - - - -0.3498 - 4.485 0.73 - 343.5 1 2 0 -0.0013 37 0 0 0 4.40E+07 2.68E+07 - - - 10.1311 0.9998 221125_WJC_METTL3_EV_vs_WT_F07.22694.22694.4 3.37E-07 15/186 K.VPSSC[160.03]PIVTVDGYVDPSGGDRFC[160.03]LGQLSNVHR.T "sp|Q13485|SMAD4_HUMAN,tr|K7EIU8|K7EIU8_HUMAN,tr|A0A087WUF3|A0A087WUF3_HUMAN" 3 3487.6613 1.1 107407 22694 4 3487.666608 872.9226 Mothers against decapentaplegic homolog 4 OS=Homo sapiens OX=9606 GN=SMAD4 PE=1 SV=1 5.3 3579 - 240167 - - - 1.5297 - 2.979 0.487 - 62 1 2 1 0.0053 32 0 0 0 2.08E+06 1.88E+06 - - - 3.793 0.9592 221125_WJC_METTL3_EV_vs_WT_F07.22697.22697.4 0.00362 9/114 R.R[166.11]K[136.11]DGVFLYFEDNAGVIVNNK[136.11].G "sp|P62829|RL23_HUMAN,tr|J3KT29|J3KT29_HUMAN,tr|J3KTJ3|J3KTJ3_HUMAN" 3 2323.2171 0.95 107408 22697 4 2323.219591 581.8116 60S ribosomal protein L23 OS=Homo sapiens OX=9606 GN=RPL23 PE=1 SV=1 6.12 3579.4 - 105161 - - - 1.0718 - 1.965 0.195 - 45.4 1 2 1 0.0025 20 0 0 0 5.60E+06 5.90E+06 - - - 1.1484 1 221125_WJC_METTL3_EV_vs_WT_F07.22699.22699.3 2.10E-14 34/88 K.HSSVYPTQEELEAVQNMVSHTER[166.11].A "sp|Q12906|ILF3_HUMAN,tr|K7EM82|K7EM82_HUMAN,tr|K7ER69|K7ER69_HUMAN,tr|K7ENK6|K7ENK6_HUMAN,tr|K7EJ09|K7EJ09_HUMAN,tr|K7ERM6|K7ERM6_HUMAN,tr|K7EKJ9|K7EKJ9_HUMAN" 7 2680.2427 0.54 107409 22699 3 2680.243285 894.4215 Interleukin enhancer-binding factor 3 OS=Homo sapiens OX=9606 GN=ILF3 PE=1 SV=3 4.87 3579.6 - 2.24E+06 - - - 0.2317 - 5.451 0.718 - 1539.2 1 2 0 0.0006 23 0 0 0 9.06E+07 1.67E+08 - - - 10.5231 1 221125_WJC_METTL3_EV_vs_WT_F07.22702.22702.3 1.40E-11 24/112 K.AAQHQANQAAVAAQAAAAAATVMTQSTAK[136.11].A tr|A0A7P0T9I3|A0A7P0T9I3_HUMAN 1 2759.3864 1.27 107412 22702 3 2759.386635 920.8028 Muscleblind-like protein 2 OS=Homo sapiens OX=9606 GN=MBNL2 PE=1 SV=1 8.8 3580 - 514973 - - - 0.0761 - 5.506 0.707 - 755.2 1 2 0 0.0002 29 0 0 0 2.82E+07 2.22E+07 - - - 10.3468 1 221125_WJC_METTL3_EV_vs_WT_F07.22705.22705.4 3.09E-13 36/150 R.HNLITEMVALNPDFK[136.11]PPADYK[136.11]PPATR[166.11].V "sp|Q15637|SF01_HUMAN,tr|A0A7P0T9U7|A0A7P0T9U7_HUMAN" 2 2960.5429 1.18 107413 22705 4 2960.547065 741.143 Splicing factor 1 OS=Homo sapiens OX=9606 GN=SF1 PE=1 SV=4 6.75 3580.4 - 3.69E+06 - - - 1.4173 - 4.483 0.671 - 971.8 1 2 0 0.0042 26 0 0 0 1.81E+08 1.53E+08 - - - 5.5385 1 221125_WJC_METTL3_EV_vs_WT_F07.22706.22706.4 1.65E-11 27/198 K.AQHTLPQDPAIVQSSLGSASASPFQPHVPYSPFR[166.11].G "sp|Q9BX40|LS14B_HUMAN,tr|Q5TBQ1|Q5TBQ1_HUMAN,tr|A0A0C4DFV2|A0A0C4DFV2_HUMAN" 3 3626.8146 1.52 107414 22706 4 3626.816193 907.7109 Protein LSM14 homolog B OS=Homo sapiens OX=9606 GN=LSM14B PE=1 SV=1 6.96 3580.5 - 574175 - - - 0.453 - 5.162 0.571 - 266.1 1 2 0 0.0016 34 0 0 0 1.54E+07 1.01E+07 - - - 4.685 1 221125_WJC_METTL3_EV_vs_WT_F07.22708.22708.4 1.14E-10 23/198 K.AQHTLPQDPAIVQSSLGSASASPFQPHVPYSPFR.G "sp|Q9BX40|LS14B_HUMAN,tr|Q5TBQ1|Q5TBQ1_HUMAN,tr|A0A0C4DFV2|A0A0C4DFV2_HUMAN" 3 3616.8063 1.52 107416 22708 4 3616.811653 905.2088 Protein LSM14 homolog B OS=Homo sapiens OX=9606 GN=LSM14B PE=1 SV=1 6.96 3580.8 - 503412 - - - 1.4856 - 4.742 0.601 - 186.8 1 2 0 0.0054 34 0 0 0 1.54E+07 1.01E+07 - - - 4.9198 1 221125_WJC_METTL3_EV_vs_WT_F07.22712.22712.3 9.36E-07 16/56 K.HSGNITFDEIVNIAR[166.11].Q sp|P30050|RL12_HUMAN 1 1694.8616 1.45 107418 22712 3 1694.864723 565.9611 60S ribosomal protein L12 OS=Homo sapiens OX=9606 GN=RPL12 PE=1 SV=1 5.32 3581.3 - 264502 - - - 1.8704 - 2.91 0.55 - 390.4 1 2 0 0.0032 15 0 0 0 1.51E+07 1.05E+07 - - - 7.4583 0.9999 221125_WJC_METTL3_EV_vs_WT_F07.22719.22719.3 1.59E-08 20/68 K.LVINGNPITIFQER[166.11]DPSK[136.11].L sp|P04406|G3P_HUMAN 1 2058.1229 1.54 107422 22719 3 2058.12573 687.0482 Glyceraldehyde-3-phosphate dehydrogenase OS=Homo sapiens OX=9606 GN=GAPDH PE=1 SV=3 6.07 3582.2 - 900546 - - - 1.3945 - 3.315 0.572 - 479.5 1 2 1 0.0029 18 0 0 0 7.01E+07 4.56E+07 - - - 7.9007 1 221125_WJC_METTL3_EV_vs_WT_F07.22722.22722.3 2.32E-12 24/120 K.VGGTNPNGGSFEEVLSSTAHASAQSLAGGSR[166.11].R "sp|Q16890|TPD53_HUMAN,tr|E9PPQ1|E9PPQ1_HUMAN,tr|J3KNE7|J3KNE7_HUMAN" 3 2954.3994 2.87 107425 22722 3 2954.404419 985.8071 Tumor protein D53 OS=Homo sapiens OX=9606 GN=TPD52L1 PE=1 SV=1 5.4 3582.6 - 295091 - - - 1.7073 - 4.397 0.695 - 426.2 1 2 0 0.005 31 0 0 0 1.76E+07 6.13E+06 - - - 9.6942 1 221125_WJC_METTL3_EV_vs_WT_F07.22726.22726.3 1.93E-15 21/160 T.VSSGYGGASGVGSGLGLGGGSSYSYGSGLGVGGGFSSSSGR.A "sp|P04259|K2C6B_HUMAN,sp|P02538|K2C6A_HUMAN" 2 3531.6138 999 107427 22726 3 3531.611348 1178.2119 "Keratin, type II cytoskeletal 6B OS=Homo sapiens OX=9606 GN=KRT6B PE=1 SV=5" 8.47 3583.1 - 474736 - - - -0.7079 - 4.278 0.746 - 175.5 1 1 0 -0.0025 41 0 0 0 9.17E+06 0.00E+00 - - - 10.2004 1 221125_WJC_METTL3_EV_vs_WT_F07.22727.22727.3 2.25E-13 30/100 K.EQVHQGGVELQQLEAGLQEAGEEDTR.L "sp|Q8NBT2|SPC24_HUMAN,tr|K7EJH0|K7EJH0_HUMAN,tr|K7EMX1|K7EMX1_HUMAN,tr|K7EJV2|K7EJV2_HUMAN,tr|K7ESQ2|K7ESQ2_HUMAN" 5 2849.3428 2.3 107428 22727 3 2849.347385 950.7882 Kinetochore protein Spc24 OS=Homo sapiens OX=9606 GN=SPC24 PE=1 SV=2 4.06 3583.2 - 823840 - - - 1.6239 - 5.406 0.687 - 1096.8 1 2 0 0.0046 26 0 0 0 3.53E+08 1.53E+08 - - - 10.0804 1 221125_WJC_METTL3_EV_vs_WT_F07.22728.22728.3 2.42E-10 17/56 K.HSGNITFDEIVNIAR.Q sp|P30050|RL12_HUMAN 1 1684.8533 1.44 107429 22728 3 1684.857071 562.625 60S ribosomal protein L12 OS=Homo sapiens OX=9606 GN=RPL12 PE=1 SV=1 5.32 3583.4 - 476900 - - - 2.2483 - 3.301 0.621 - 486.1 1 2 0 0.0038 15 0 0 0 1.51E+07 1.05E+07 - - - 8.5787 1 221125_WJC_METTL3_EV_vs_WT_F07.22733.22733.4 2.77E-07 22/108 K.NTHATTHNAYDLEVIDIFK[136.11].L "sp|P09874|PARP1_HUMAN,tr|A0A7I2V3E1|A0A7I2V3E1_HUMAN" 2 2209.0895 1.11 107432 22733 4 2209.088986 553.2797 Poly [ADP-ribose] polymerase 1 OS=Homo sapiens OX=9606 GN=PARP1 PE=1 SV=4 5.21 3584 - 1.14E+06 - - - -0.2313 - 3.508 0.639 - 399.7 1 2 0 -0.0005 19 0 0 0 6.81E+07 6.12E+07 - - - 5.2123 1 221125_WJC_METTL3_EV_vs_WT_F07.22735.22735.4 6.74E-12 25/186 R.KTLSGFSSTSVLPHTGYIYHSDIVQSLPPDLR.R "sp|Q8WWY3|PRP31_HUMAN,tr|E7EVX8|E7EVX8_HUMAN" 2 3514.8096 8.64 107434 22735 4 3514.812791 879.7097 U4\U6 small nuclear ribonucleoprotein Prp31 OS=Homo sapiens OX=9606 GN=PRPF31 PE=1 SV=2 6.92 3584.3 - 729991 - - - 0.8979 - 4.508 0.596 - 269.8 1 2 0 0.0032 32 0 0 0 2.97E+07 3.43E+06 - - - 4.8674 0.9999 221125_WJC_METTL3_EV_vs_WT_F07.22736.22736.4 1.31E-08 20/156 R.MK[136.11]EEQVQGPVELLSIPEDAPEK[136.11]DWTSR[166.11].E "sp|Q9H501|ESF1_HUMAN,tr|A0A087WX71|A0A087WX71_HUMAN" 2 3136.5597 1.18 107435 22736 4 3136.561921 785.1472 ESF1 homolog OS=Homo sapiens OX=9606 GN=ESF1 PE=1 SV=1 4.25 3584.4 - 691247 - - - 0.7078 - 3.237 0.554 - 120.4 1 2 2 0.0022 27 0 0 0 2.56E+07 2.18E+07 - - - 4.4149 1 221125_WJC_METTL3_EV_vs_WT_F07.22742.22742.4 2.29E-10 23/108 K.NTHATTHNAYDLEVIDIFK.L "sp|P09874|PARP1_HUMAN,tr|A0A7I2V3E1|A0A7I2V3E1_HUMAN" 2 2201.0753 1.11 107439 22742 4 2201.077524 551.2761 Poly [ADP-ribose] polymerase 1 OS=Homo sapiens OX=9606 GN=PARP1 PE=1 SV=4 5.21 3585.1 - 1.72E+06 - - - 1.0118 - 3.323 0.655 - 394.3 1 2 0 0.0022 19 0 0 0 6.76E+07 6.11E+07 - - - 5.3327 0.9999 221125_WJC_METTL3_EV_vs_WT_F07.22743.22743.3 1.49E-07 Dec-80 R.SNASLTNNQNLIQSLK[136.11]EDLNK[136.11].V sp|P12270|TPR_HUMAN 1 2359.2314 3.26 107440 22743 3 2359.229594 787.4177 Nucleoprotein TPR OS=Homo sapiens OX=9606 GN=TPR PE=1 SV=3 5.79 3585.2 - 785302 - - - -0.7727 - 2.714 0.5 - 126.2 1 2 1 -0.0018 21 0 0 0 1.47E+08 4.51E+07 - - - 6.5077 0.9984 221125_WJC_METTL3_EV_vs_WT_F07.22744.22744.4 8.51E-06 35/216 R.PLSLDGADSAPPPPAPSAPPPHHSQGFSVDNIMTSLR.G sp|Q12948|FOXC1_HUMAN 1 3759.8315 3.65 107441 22744 4 3759.829574 940.9652 Forkhead box protein C1 OS=Homo sapiens OX=9606 GN=FOXC1 PE=1 SV=3 5.14 3585.4 - 1.32E+06 - - - -0.5147 - 5.176 0.601 - 422.2 1 1 0 -0.0019 37 0 0 0 9.41E+07 2.58E+07 - - - 4.9385 1 221125_WJC_METTL3_EV_vs_WT_F07.22749.22749.3 1.63E-09 26/72 K.NTHATTHNAYDLEVIDIFK[136.11].L "sp|P09874|PARP1_HUMAN,tr|A0A7I2V3E1|A0A7I2V3E1_HUMAN" 2 2209.0895 0.92 107444 22749 3 2210.088399 737.3704 Poly [ADP-ribose] polymerase 1 OS=Homo sapiens OX=9606 GN=PARP1 PE=1 SV=4 5.21 3586.1 - 871641 - - - 452.1781 - 4.444 0.647 - 891.5 1 2 0 0.9989 19 0 0 0 3.54E+07 3.86E+07 - - - 9.1412 1 221125_WJC_METTL3_EV_vs_WT_F07.22753.22753.4 3.06E-10 23/150 K.EQVHQGGVELQQLEAGLQEAGEEDTR.L "sp|Q8NBT2|SPC24_HUMAN,tr|K7EJH0|K7EJH0_HUMAN,tr|K7EMX1|K7EMX1_HUMAN,tr|K7EJV2|K7EJV2_HUMAN,tr|K7ESQ2|K7ESQ2_HUMAN" 5 2849.3428 1.64 107447 22753 4 2849.347741 713.343 Kinetochore protein Spc24 OS=Homo sapiens OX=9606 GN=SPC24 PE=1 SV=2 4.06 3586.5 - 735509 - - - 1.7488 - 3.469 0.569 - 78.4 1 2 0 0.005 26 0 0 0 2.81E+07 1.71E+07 - - - 4.5696 1 221125_WJC_METTL3_EV_vs_WT_F07.22761.22761.4 1.55E-05 19/180 R.QYQHGSVSDTVFDSIPANPALLTYPR[166.11]PGTSR[166.11].S sp|Q99959|PKP2_HUMAN 1 3393.6857 5.22 107453 22761 4 3393.684453 849.4287 Plakophilin-2 OS=Homo sapiens OX=9606 GN=PKP2 PE=1 SV=2 6.75 3587.5 - 682998 - - - -0.3551 - 2.7 0.552 - 91.5 1 2 0 -0.0012 31 0 0 0 1.02E+08 1.96E+07 - - - 4.3321 0.999 221125_WJC_METTL3_EV_vs_WT_F07.22762.22762.3 3.59E-09 23/164 S.TVSSGYGGASGVGSGLGLGGGSSYSYGSGLGVGGGFSSSSGR.A "sp|P04259|K2C6B_HUMAN,sp|P02538|K2C6A_HUMAN" 2 3632.6615 999 107454 22762 3 3632.658197 1211.8945 "Keratin, type II cytoskeletal 6B OS=Homo sapiens OX=9606 GN=KRT6B PE=1 SV=5" 8.16 3587.6 - 404524 - - - -0.9164 - 3.136 0.652 - 240 1 1 0 -0.0033 42 0 0 0 1.02E+07 0.00E+00 - - - 8.4377 1 221125_WJC_METTL3_EV_vs_WT_F07.22763.22763.2 2.04E-08 Dec-34 K.SSGPTSLFAVTVAPPGAR[166.11].Q "sp|Q00839|HNRPU_HUMAN,tr|A0A1W2PP35|A0A1W2PP35_HUMAN,tr|A0A1W2PPS1|A0A1W2PPS1_HUMAN,tr|A0A1W2PP22|A0A1W2PP22_HUMAN,tr|A0A1X7SBS1|A0A1X7SBS1_HUMAN" 5 1723.9133 1.01 107455 22763 2 1723.910129 862.9639 Heterogeneous nuclear ribonucleoprotein U OS=Homo sapiens OX=9606 GN=HNRNPU PE=1 SV=6 9.47 3587.8 - 196455 - - - -1.8127 - 2.376 0.622 - 435.7 1 2 0 -0.0031 18 0 0 0 6.59E+06 6.55E+06 - - - 5.7618 1 221125_WJC_METTL3_EV_vs_WT_F07.22768.22768.4 5.16E-14 39/222 K.GILGYTEHQVVSSDFNSDTHSSTFDAGAGIALNDHFVK.L "sp|P04406|G3P_HUMAN,tr|E7EUT5|E7EUT5_HUMAN" 2 4035.8875 0.96 107458 22768 4 4035.882433 1009.9792 Glyceraldehyde-3-phosphate dehydrogenase OS=Homo sapiens OX=9606 GN=GAPDH PE=1 SV=3 4.7 3588.4 - 2.99E+06 - - - -1.2565 - 5.771 0.752 - 566.1 1 2 0 -0.0051 38 0 0 0 1.20E+08 1.25E+08 - - - 6.2811 0.9999 221125_WJC_METTL3_EV_vs_WT_F07.22781.22781.4 4.21E-09 23/186 K.LKDEVLKETVSQRPGATVPTDFATFPSSAFLR.A "sp|Q14203|DCTN1_HUMAN,tr|A0A804CDA6|A0A804CDA6_HUMAN,tr|E7EX90|E7EX90_HUMAN,tr|A0A7P0Z4C3|A0A7P0Z4C3_HUMAN,tr|E7EWF7|E7EWF7_HUMAN" 5 3506.8409 1.97 107464 22781 4 3506.839288 877.7175 Dynactin subunit 1 OS=Homo sapiens OX=9606 GN=DCTN1 PE=1 SV=3 6.21 3590 - 932386 - - - -0.4697 - 3.38 0.581 - 136.1 1 2 2 -0.0016 32 0 0 0 2.34E+07 1.19E+07 - - - 4.6503 1 221125_WJC_METTL3_EV_vs_WT_F07.22782.22782.4 1.39E-09 22/114 R.K[136.11]NDPQSITADDLHQLLVVAR[166.11].C sp|Q9BTE3|MCMBP_HUMAN 1 2250.2087 0.38 107465 22782 4 2250.21047 563.5595 Mini-chromosome maintenance complex-binding protein OS=Homo sapiens OX=9606 GN=MCMBP PE=1 SV=2 5.3 3590.2 - 426453 - - - 0.7799 - 3.055 0.596 - 256.2 1 2 0 0.0018 20 0 0 0 5.02E+06 1.31E+07 - - - 4.7865 0.9988 221125_WJC_METTL3_EV_vs_WT_F07.22787.22787.3 9.20E-11 21/80 C.LAISTPDAPATQDGVESLLQK[136.11].F "sp|Q86U44|MTA70_HUMAN,tr|B4E349|B4E349_HUMAN,tr|F5H6D8|F5H6D8_HUMAN,tr|H0YFV6|H0YFV6_HUMAN,tr|B4DTN4|B4DTN4_HUMAN" 5 2161.1358 0 107468 22787 3 2161.134026 721.3859 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 4.03 3590.8 - 1.55E+06 - - - -0.8111 - 3.637 0.569 - 530.1 1 1 0 -0.0018 21 0 0 0 5.72E+04 4.51E+07 - - - 7.9788 1 221125_WJC_METTL3_EV_vs_WT_F07.22789.22789.3 2.99E-12 17/168 Q.STVSSGYGGASGVGSGLGLGGGSSYSYGSGLGVGGGFSSSSGR.A "sp|P04259|K2C6B_HUMAN,sp|P02538|K2C6A_HUMAN" 2 3719.6936 999 107470 22789 3 3719.694875 1240.9051 "Keratin, type II cytoskeletal 6B OS=Homo sapiens OX=9606 GN=KRT6B PE=1 SV=5" 8.22 3591 - 680123 - - - 0.3549 - 3.716 0.729 - 110.7 1 1 0 0.0013 43 0 0 0 2.41E+07 0.00E+00 - - - 9.6872 1 221125_WJC_METTL3_EV_vs_WT_F07.22804.22804.4 7.97E-12 27/156 R.MKEEQVQGPVELLSIPEDAPEKDWTSR.E "sp|Q9H501|ESF1_HUMAN,tr|A0A087WX71|A0A087WX71_HUMAN" 2 3110.523 0.76 107476 22804 4 3110.524981 778.638 ESF1 homolog OS=Homo sapiens OX=9606 GN=ESF1 PE=1 SV=1 4.25 3593.2 - 606769 - - - 0.6269 - 4.386 0.687 - 311.1 1 2 2 0.002 27 0 0 0 1.61E+07 2.11E+07 - - - 5.6677 1 221125_WJC_METTL3_EV_vs_WT_F07.22806.22806.4 1.80E-09 29/132 K.HSSVYPTQEELEAVQNMVSHTER[166.11].A "sp|Q12906|ILF3_HUMAN,tr|K7EM82|K7EM82_HUMAN,tr|K7ER69|K7ER69_HUMAN,tr|K7ENK6|K7ENK6_HUMAN,tr|K7EJ09|K7EJ09_HUMAN,tr|K7ERM6|K7ERM6_HUMAN,tr|K7EKJ9|K7EKJ9_HUMAN" 7 2680.2427 1.31 107477 22806 4 2680.233044 671.0679 Interleukin enhancer-binding factor 3 OS=Homo sapiens OX=9606 GN=ILF3 PE=1 SV=3 4.87 3593.4 - 2.92E+06 - - - -3.5892 - 4.404 0.616 - 529.5 1 2 0 -0.0096 23 0 0 0 4.87E+08 3.71E+08 - - - 5.0653 1 221125_WJC_METTL3_EV_vs_WT_F07.22812.22812.3 8.68E-06 15/96 K.QYNGVPLDGR[166.11]PMNIQLVTSQIDAQR[166.11].R "sp|Q86V81|THOC4_HUMAN,tr|E9PB61|E9PB61_HUMAN" 2 2832.4456 0.51 107481 22812 3 2832.444369 945.1558 THO complex subunit 4 OS=Homo sapiens OX=9606 GN=ALYREF PE=1 SV=3 5.96 3594.2 - 1.05E+06 - - - -0.4173 - 2.7 0.496 - 103.3 1 2 0 -0.0012 25 0 0 0 3.30E+07 6.43E+07 - - - 6.3547 0.9996 221125_WJC_METTL3_EV_vs_WT_F07.22813.22813.4 0.000217 14/186 K.LK[136.11]DEVLK[136.11]ETVSQR[166.11]PGATVPTDFATFPSSAFLR[166.11].A "sp|Q14203|DCTN1_HUMAN,tr|A0A804CDA6|A0A804CDA6_HUMAN,tr|E7EX90|E7EX90_HUMAN,tr|A0A7P0Z4C3|A0A7P0Z4C3_HUMAN,tr|E7EWF7|E7EWF7_HUMAN" 5 3542.8859 5.15 107482 22813 4 3542.896165 886.7287 Dynactin subunit 1 OS=Homo sapiens OX=9606 GN=DCTN1 PE=1 SV=3 6.21 3594.3 - 366022 - - - 2.9044 - 2.826 0.502 - 51.2 1 2 2 0.0103 32 0 0 0 6.33E+07 1.23E+07 - - - 3.9062 1 221125_WJC_METTL3_EV_vs_WT_F07.22814.22814.3 2.84E-17 33/124 R.K[136.11]ELEQVC[160.03]NPIISGLYQGAGGPGPGGFGAQGPK[136.11].G "sp|P0DMV8|HS71A_HUMAN,sp|P0DMV9|HS71B_HUMAN,tr|V9GZ37|V9GZ37_HUMAN,tr|A0A0G2JIW1|A0A0G2JIW1_HUMAN" 4 3198.6103 0.01 107483 22814 3 3198.619001 1067.2107 Heat shock 70 kDa protein 1A OS=Homo sapiens OX=9606 GN=HSPA1A PE=1 SV=1 6.13 3594.4 - 582091 - - - 2.7256 - 5.798 0.768 - 1154 1 2 0 0.0087 32 0 0 0 2.49E+05 2.87E+07 - - - 11.1434 1 221125_WJC_METTL3_EV_vs_WT_F07.22815.22815.4 6.48E-07 16/132 R.HTIHIGSGGGSDMFGDISFLQGK.F sp|O14613|BORG1_HUMAN 1 2360.1219 1.44 107484 22815 4 2360.127356 591.0378 Cdc42 effector protein 2 OS=Homo sapiens OX=9606 GN=CDC42EP2 PE=1 SV=1 5.98 3594.6 - 544922 - - - 2.299 - 3.243 0.569 - 140.5 1 2 0 0.0054 23 0 0 0 6.61E+06 4.60E+06 - - - 4.5582 0.9143 221125_WJC_METTL3_EV_vs_WT_F07.22816.22816.2 0.00034 Jul-40 C.LAISTPDAPATQDGVESLLQK[136.11].F "sp|Q86U44|MTA70_HUMAN,tr|B4E349|B4E349_HUMAN,tr|F5H6D8|F5H6D8_HUMAN,tr|H0YFV6|H0YFV6_HUMAN,tr|B4DTN4|B4DTN4_HUMAN" 5 2161.1358 0.05 107485 22816 2 2161.128693 1081.5752 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 4.03 3594.7 - 176895 - - - -3.2788 - 1.84 0.42 - 87.6 1 1 0 -0.0071 21 0 0 0 1.47E+05 2.94E+06 - - - 3.64 1 221125_WJC_METTL3_EV_vs_WT_F07.22821.22821.3 1.07E-09 21/96 K.QYNGVPLDGRPMNIQLVTSQIDAQR.R "sp|Q86V81|THOC4_HUMAN,tr|E9PB61|E9PB61_HUMAN" 2 2812.429 0.51 107488 22821 3 2812.430803 938.4836 THO complex subunit 4 OS=Homo sapiens OX=9606 GN=ALYREF PE=1 SV=3 5.96 3595.4 - 945663 - - - 0.6372 - 3.068 0.588 - 280.1 1 2 0 0.0018 25 0 0 0 3.30E+07 6.43E+07 - - - 7.6742 0.9996 221125_WJC_METTL3_EV_vs_WT_F07.22828.22828.4 0.000496 17/162 K.EFHLEYDK[136.11]LEER[166.11]PHLPSTFNYNPAQQAF.- "sp|Q9NZN8|CNOT2_HUMAN,tr|F8VUB4|F8VUB4_HUMAN,tr|F8VV52|F8VV52_HUMAN" 3 3437.6436 18.35 107492 22828 4 3437.641293 860.4182 CCR4-NOT transcription complex subunit 2 OS=Homo sapiens OX=9606 GN=CNOT2 PE=1 SV=1 4.92 3596.3 - 393894 - - - -0.6638 - 3.35 0.42 - 126 1 2 1 -0.0023 28 0 0 0 1.25E+08 6.81E+06 - - - 3.2564 0.9999 221125_WJC_METTL3_EV_vs_WT_F07.22838.22838.4 3.61E-05 15/108 R.FAHIDGDHLTLLNVYHAFK[136.11].Q sp|O43143|DHX15_HUMAN 1 2218.1415 0.88 107497 22838 4 2218.145065 555.5426 Pre-mRNA-splicing factor ATP-dependent RNA helicase DHX15 OS=Homo sapiens OX=9606 GN=DHX15 PE=1 SV=2 6.26 3597.7 - 209725 - - - 1.6194 - 3.131 0.476 - 182 1 2 0 0.0036 19 0 0 0 6.54E+06 7.45E+06 - - - 3.7542 0.9992 221125_WJC_METTL3_EV_vs_WT_F07.22839.22839.4 0.000315 Nov-84 R.GPSWDPFR[166.11]DWYPHSR[166.11].L "sp|P04792|HSPB1_HUMAN,tr|A0A6Q8PGY2|A0A6Q8PGY2_HUMAN,tr|A0A6Q8PHJ6|A0A6Q8PHJ6_HUMAN,tr|A0A6Q8PHA6|A0A6Q8PHA6_HUMAN,tr|A0A6Q8PF43|A0A6Q8PF43_HUMAN,tr|A0A6Q8PFK8|A0A6Q8PFK8_HUMAN,tr|A0A6Q8PGK1|A0A6Q8PGK1_HUMAN,tr|A0A6Q8PH65|A0A6Q8PH65_HUMAN,tr|A0A6Q8PFE7|A0A6Q8PFE7_HUMAN" 9 1921.8763 1.46 107498 22839 4 1921.88149 481.4764 Heat shock protein beta-1 OS=Homo sapiens OX=9606 GN=HSPB1 PE=1 SV=2 6.75 3597.8 - 148359 - - - 2.6974 - 1.99 0.444 - 101.6 1 2 1 0.0052 15 0 0 0 1.03E+07 7.07E+06 - - - 3.3354 0.9067 221125_WJC_METTL3_EV_vs_WT_F07.22844.22844.4 3.68E-08 14/222 F.GAVGVAGSSLTSFGTETSNSGTLPQSSAVGSAFTQDTR[166.11].S "sp|Q8ND56|LS14A_HUMAN,tr|A0A140TA76|A0A140TA76_HUMAN,tr|K7EMZ9|K7EMZ9_HUMAN" 3 3641.7321 0.86 107501 22844 4 3642.736873 911.4403 Protein LSM14 homolog A OS=Homo sapiens OX=9606 GN=LSM14A PE=1 SV=3 4.37 3598.5 - 420582 - - - 275.9157 - 2.868 0.53 - 72 1 1 0 1.0048 38 0 0 0 2.17E+07 2.53E+07 - - - 3.868 1 221125_WJC_METTL3_EV_vs_WT_F07.22845.22845.4 1.48E-07 32/162 K.EQVHQGGVELQQLEAGLQEAGEEDTRLK.A "sp|Q8NBT2|SPC24_HUMAN,tr|K7EJH0|K7EJH0_HUMAN,tr|K7EMX1|K7EMX1_HUMAN,tr|K7EJV2|K7EJV2_HUMAN,tr|K7ESQ2|K7ESQ2_HUMAN" 5 3090.5218 2.89 107502 22845 4 3090.538659 773.6377 Kinetochore protein Spc24 OS=Homo sapiens OX=9606 GN=SPC24 PE=1 SV=2 4.3 3598.6 - 401635 - - - 5.4599 - 5.316 0.618 - 631.4 1 2 1 0.0169 28 0 0 0 6.85E+07 2.37E+07 - - - 5.1191 0.8714 221125_WJC_METTL3_EV_vs_WT_F07.22846.22846.4 0.0114 10/180 R.QYQHGSVSDTVFDSIPANPALLTYPRPGTSR.S sp|Q99959|PKP2_HUMAN 1 3373.6691 5.22 107503 22846 4 3373.692362 844.4246 Plakophilin-2 OS=Homo sapiens OX=9606 GN=PKP2 PE=1 SV=2 6.75 3598.7 - 321674 - - - 6.8898 - 1.664 0.253 - 19.4 1 2 0 0.0232 31 0 0 0 1.02E+08 1.96E+07 - - - 1.5764 1 221125_WJC_METTL3_EV_vs_WT_F07.22851.22851.3 8.25E-09 27/100 K.AK[136.11]C[160.03]ELSSSVQTDINLPYLTMDSSGPK[136.11].H "sp|P38646|GRP75_HUMAN,tr|H0Y8K0|H0Y8K0_HUMAN,tr|A0A7I2V2G2|A0A7I2V2G2_HUMAN,tr|A0A7I2V3F7|A0A7I2V3F7_HUMAN,tr|A0A7I2YQB2|A0A7I2YQB2_HUMAN,tr|D6RCD7|D6RCD7_HUMAN" 6 2856.3856 0.29 107505 22851 3 2856.387816 953.1358 "Stress-70 protein, mitochondrial OS=Homo sapiens OX=9606 GN=HSPA9 PE=1 SV=2" 4.56 3599.3 - 1.42E+06 - - - 0.772 - 4.647 0.664 - 439.4 1 2 1 0.0022 26 0 0 0 8.37E+06 2.86E+07 - - - 9.4766 1 221125_WJC_METTL3_EV_vs_WT_F07.22852.22852.4 5.85E-12 22/126 K.C[160.03]QEVISWLDANTLAEK[136.11]DEFEHK[136.11].R "sp|P0DMV8|HS71A_HUMAN,sp|P0DMV9|HS71B_HUMAN,tr|V9GZ37|V9GZ37_HUMAN,tr|A0A0G2JIW1|A0A0G2JIW1_HUMAN" 4 2677.2665 0.09 107506 22852 4 2677.275469 670.3239 Heat shock 70 kDa protein 1A OS=Homo sapiens OX=9606 GN=HSPA1A PE=1 SV=1 4.35 3599.5 - 909870 - - - 3.3568 - 4.196 0.622 - 410.2 1 2 1 0.009 22 0 0 0 2.22E+06 2.51E+07 - - - 5.1067 1 221125_WJC_METTL3_EV_vs_WT_F07.22866.22866.4 2.75E-11 25/222 F.GAVGVAGSSLTSFGTETSNSGTLPQSSAVGSAFTQDTR.S "sp|Q8ND56|LS14A_HUMAN,tr|A0A140TA76|A0A140TA76_HUMAN,tr|K7EMZ9|K7EMZ9_HUMAN" 3 3631.7238 0.86 107515 22866 4 3631.723382 908.9382 Protein LSM14 homolog A OS=Homo sapiens OX=9606 GN=LSM14A PE=1 SV=3 4.37 3601.3 - 1.35E+06 - - - -0.1129 - 4.733 0.632 - 252.9 1 1 0 -0.0004 38 0 0 0 2.17E+07 2.53E+07 - - - 5.1801 1 221125_WJC_METTL3_EV_vs_WT_F07.22867.22867.3 2.95E-11 24/148 F.GAVGVAGSSLTSFGTETSNSGTLPQSSAVGSAFTQDTR[166.11].S "sp|Q8ND56|LS14A_HUMAN,tr|A0A140TA76|A0A140TA76_HUMAN,tr|K7EMZ9|K7EMZ9_HUMAN" 3 3641.7321 0.95 107516 22867 3 3641.734682 1214.918 Protein LSM14 homolog A OS=Homo sapiens OX=9606 GN=LSM14A PE=1 SV=3 4.37 3601.4 - 947684 - - - 0.7194 - 4.146 0.697 - 304.6 1 1 0 0.0026 38 0 0 0 1.61E+07 1.69E+07 - - - 9.582 1 221125_WJC_METTL3_EV_vs_WT_F07.22868.22868.3 5.41E-12 20/100 K.AKC[160.03]ELSSSVQTDINLPYLTMDSSGPK.H "sp|P38646|GRP75_HUMAN,tr|H0Y8K0|H0Y8K0_HUMAN,tr|A0A7I2V2G2|A0A7I2V2G2_HUMAN,tr|A0A7I2V3F7|A0A7I2V3F7_HUMAN,tr|A0A7I2YQB2|A0A7I2YQB2_HUMAN,tr|D6RCD7|D6RCD7_HUMAN" 6 2840.3572 0.29 107517 22868 3 2840.35447 947.793 "Stress-70 protein, mitochondrial OS=Homo sapiens OX=9606 GN=HSPA9 PE=1 SV=2" 4.56 3601.6 - 496142 - - - -0.965 - 4.486 0.632 - 267.5 1 2 1 -0.0027 26 0 0 0 8.37E+06 2.86E+07 - - - 9.0386 0.9384 221125_WJC_METTL3_EV_vs_WT_F07.22877.22877.3 2.00E-05 13/116 K.TPSTMENDSSNLDPSQAPSLAQPLVFSNSK.Q "sp|Q14157|UBP2L_HUMAN,tr|F8W726|F8W726_HUMAN,tr|Q5VU77|Q5VU77_HUMAN" 3 3161.4823 -1 107524 22877 3 3162.464548 1054.8347 Ubiquitin-associated protein 2-like OS=Homo sapiens OX=9606 GN=UBAP2L PE=1 SV=2 4.03 3602.7 - 577619 - - - 310.696 - 1.945 0.56 - 74 1 2 0 0.9823 30 0 0 0 0.00E+00 0.00E+00 - - - 6.0419 0.9993 221125_WJC_METTL3_EV_vs_WT_F07.22878.22878.3 5.76E-06 Oct-56 R.GPSWDPFRDWYPHSR.L "sp|P04792|HSPB1_HUMAN,tr|A0A6Q8PGY2|A0A6Q8PGY2_HUMAN,tr|A0A6Q8PHJ6|A0A6Q8PHJ6_HUMAN,tr|A0A6Q8PHA6|A0A6Q8PHA6_HUMAN,tr|A0A6Q8PF43|A0A6Q8PF43_HUMAN,tr|A0A6Q8PFK8|A0A6Q8PFK8_HUMAN,tr|A0A6Q8PGK1|A0A6Q8PGK1_HUMAN,tr|A0A6Q8PH65|A0A6Q8PH65_HUMAN,tr|A0A6Q8PFE7|A0A6Q8PFE7_HUMAN" 9 1901.8598 1.88 107525 22878 3 1901.853481 634.9605 Heat shock protein beta-1 OS=Homo sapiens OX=9606 GN=HSPB1 PE=1 SV=2 6.75 3602.8 - 318007 - - - -3.3047 - 2.158 0.533 - 100.7 1 2 1 -0.0063 15 0 0 0 3.46E+06 1.84E+06 - - - 6.4878 1 221125_WJC_METTL3_EV_vs_WT_F07.22884.22884.4 1.10E-12 23/162 K.TSPKPAVVETVTTAKPQQIQALMDEVTK.Q "sp|P56192|SYMC_HUMAN,tr|H0YIP0|H0YIP0_HUMAN,tr|H0YI94|H0YI94_HUMAN" 3 3009.6056 0.97 107527 22884 4 3009.604612 753.4087 "Methionine--tRNA ligase, cytoplasmic OS=Homo sapiens OX=9606 GN=MARS1 PE=1 SV=2" 5.85 3603.6 - 1.27E+06 - - - -0.3409 - 4.279 0.597 - 380.9 1 2 0 -0.001 28 0 0 0 9.33E+07 9.64E+07 - - - 4.8734 0.9998 221125_WJC_METTL3_EV_vs_WT_F07.22886.22886.4 6.00E-05 15/84 R.GPSWDPFRDWYPHSR.L "sp|P04792|HSPB1_HUMAN,tr|A0A6Q8PGY2|A0A6Q8PGY2_HUMAN,tr|A0A6Q8PHJ6|A0A6Q8PHJ6_HUMAN,tr|A0A6Q8PHA6|A0A6Q8PHA6_HUMAN,tr|A0A6Q8PF43|A0A6Q8PF43_HUMAN,tr|A0A6Q8PFK8|A0A6Q8PFK8_HUMAN,tr|A0A6Q8PGK1|A0A6Q8PGK1_HUMAN,tr|A0A6Q8PH65|A0A6Q8PH65_HUMAN,tr|A0A6Q8PFE7|A0A6Q8PFE7_HUMAN" 9 1901.8598 1.46 107528 22886 4 1901.858685 476.4722 Heat shock protein beta-1 OS=Homo sapiens OX=9606 GN=HSPB1 PE=1 SV=2 6.75 3603.8 - 543483 - - - -0.5684 - 2.103 0.479 - 113.5 1 2 1 -0.0011 15 0 0 0 1.03E+07 7.07E+06 - - - 3.6609 1 221125_WJC_METTL3_EV_vs_WT_F07.22890.22890.4 4.27E-12 29/162 K.NHGLSDEHVFEVIC[160.03]PSIPGYGFSEASSK.K sp|P07099|HYEP_HUMAN 1 3062.408 0.68 107530 22890 4 3062.402786 766.6093 Epoxide hydrolase 1 OS=Homo sapiens OX=9606 GN=EPHX1 PE=1 SV=1 4.8 3604.4 - 1.05E+06 - - - -1.7029 - 4.638 0.656 - 547.2 1 2 0 -0.0052 28 0 0 0 1.44E+07 2.11E+07 - - - 5.4107 1 221125_WJC_METTL3_EV_vs_WT_F07.22891.22891.4 9.73E-11 31/162 K.EQVHQGGVELQQLEAGLQEAGEEDTR[166.11]LK[136.11].A "sp|Q8NBT2|SPC24_HUMAN,tr|K7EJH0|K7EJH0_HUMAN,tr|K7EMX1|K7EMX1_HUMAN,tr|K7EJV2|K7EJV2_HUMAN,tr|K7ESQ2|K7ESQ2_HUMAN" 5 3108.5443 2.8 107531 22891 4 3108.540828 778.1433 Kinetochore protein Spc24 OS=Homo sapiens OX=9606 GN=SPC24 PE=1 SV=2 4.3 3604.5 - 1.48E+06 - - - -1.1024 - 5.377 0.632 - 641.1 1 2 1 -0.0034 28 0 0 0 6.86E+07 2.45E+07 - - - 5.2482 0.9999 221125_WJC_METTL3_EV_vs_WT_F07.22892.22892.4 4.09E-09 18/114 K.KQELEVLTANIQDLKEEYSR.K "sp|Q9HBM1|SPC25_HUMAN,tr|C9JW94|C9JW94_HUMAN" 2 2405.2438 1.5 107532 22892 4 2405.244999 602.3182 Kinetochore protein Spc25 OS=Homo sapiens OX=9606 GN=SPC25 PE=1 SV=1 4.59 3604.6 - 398927 - - - 0.4906 - 3.506 0.564 - 285 1 2 1 0.0012 20 0 0 0 1.44E+08 9.58E+07 - - - 4.5541 1 221125_WJC_METTL3_EV_vs_WT_F07.22902.22902.4 0.00481 19/132 R.K[136.11]TSQLLETLNQLSTHTHVVDITR[166.11].T "sp|Q14203|DCTN1_HUMAN,tr|A0A804CDA6|A0A804CDA6_HUMAN,tr|E7EX90|E7EX90_HUMAN,tr|A0A7P0Z4C3|A0A7P0Z4C3_HUMAN,tr|E7EWF7|E7EWF7_HUMAN" 5 2651.4361 2.24 107538 22902 4 2651.430424 663.8663 Dynactin subunit 1 OS=Homo sapiens OX=9606 GN=DCTN1 PE=1 SV=3 6.92 3605.8 - 482216 - - - -2.1592 - 4.088 0.51 - 342.5 1 2 0 -0.0057 23 0 0 0 1.20E+07 5.36E+06 - - - 4.1196 1 221125_WJC_METTL3_EV_vs_WT_F07.22907.22907.3 1.63E-15 26/76 K.KQELEVLTANIQDLKEEYSR.K "sp|Q9HBM1|SPC25_HUMAN,tr|C9JW94|C9JW94_HUMAN" 2 2405.2438 7.04 107541 22907 3 2405.242957 802.7552 Kinetochore protein Spc25 OS=Homo sapiens OX=9606 GN=SPC25 PE=1 SV=1 4.59 3606.5 - 1.10E+06 - - - -0.3584 - 5.568 0.603 - 1039.9 1 2 1 -0.0009 20 0 0 0 9.98E+07 1.42E+07 - - - 9.4282 1 221125_WJC_METTL3_EV_vs_WT_F07.22914.22914.4 1.48E-07 20/162 R.QVASHVGLHSASIPGILALDLC[160.03]PSDTNK[136.11].L "sp|Q9UMS4|PRP19_HUMAN,tr|F5GY56|F5GY56_HUMAN" 2 2907.5004 1.21 107546 22914 4 2907.494 727.8824 Pre-mRNA-processing factor 19 OS=Homo sapiens OX=9606 GN=PRPF19 PE=1 SV=1 5.98 3607.4 - 1.47E+06 - - - -2.1985 - 3.162 0.59 - 178.3 1 2 0 -0.0064 28 0 0 0 3.32E+08 2.74E+08 - - - 4.717 1 221125_WJC_METTL3_EV_vs_WT_F07.22921.22921.4 8.50E-07 21/144 K.KHISQISVAEDDDESLLGHLMIVGK.K sp|P49773|HINT1_HUMAN 1 2733.4007 2.28 107549 22921 4 2733.402381 684.3575 Adenosine 5'-monophosphoramidase HINT1 OS=Homo sapiens OX=9606 GN=HINT1 PE=1 SV=2 4.8 3608.3 - 1.13E+06 - - - 0.6036 - 4.313 0.615 - 325.7 1 2 0 0.0016 25 0 0 0 4.45E+07 1.95E+07 - - - 5.0435 1 221125_WJC_METTL3_EV_vs_WT_F07.22922.22922.4 5.53E-07 17/96 K.DITELFSQLHVSSKPEK.L "sp|Q9NRY5|F1142_HUMAN,tr|E7ESJ7|E7ESJ7_HUMAN" 2 1957.0157 1.17 107550 22922 4 1957.011584 490.2612 Protein FAM114A2 OS=Homo sapiens OX=9606 GN=FAM114A2 PE=1 SV=4 5.45 3608.4 - 535867 - - - -2.0812 - 2.972 0.516 - 141.7 1 2 0 -0.0041 17 0 0 0 1.02E+07 8.69E+06 - - - 4.0943 1 221125_WJC_METTL3_EV_vs_WT_F07.22928.22928.4 4.97E-07 29/162 K.TSPK[136.11]PAVVETVTTAK[136.11]PQQIQALMDEVTK[136.11].Q "sp|P56192|SYMC_HUMAN,tr|H0YIP0|H0YIP0_HUMAN,tr|H0YI94|H0YI94_HUMAN" 3 3033.6482 0.97 107553 22928 4 3033.643787 759.4193 "Methionine--tRNA ligase, cytoplasmic OS=Homo sapiens OX=9606 GN=MARS1 PE=1 SV=2" 5.85 3609.1 - 2.69E+06 - - - -1.4672 - 5.161 0.601 - 727.1 1 2 0 -0.0045 28 0 0 0 9.33E+07 9.64E+07 - - - 4.9654 0.9995 221125_WJC_METTL3_EV_vs_WT_F07.22932.22932.3 0.00211 Dec-64 K.DITELFSQLHVSSKPEK.L "sp|Q9NRY5|F1142_HUMAN,tr|E7ESJ7|E7ESJ7_HUMAN" 2 1957.0157 1.57 107556 22932 3 1957.011636 653.3458 Protein FAM114A2 OS=Homo sapiens OX=9606 GN=FAM114A2 PE=1 SV=4 5.45 3609.6 - 251890 - - - -2.0547 - 2.122 0.345 - 104.9 1 2 0 -0.004 17 0 0 0 8.02E+06 5.11E+06 - - - 4.286 0.9999 221125_WJC_METTL3_EV_vs_WT_F07.22941.22941.4 2.14E-09 15/162 R.QLTEEQNTLNISFQQATHQLEEKENQIK.S "sp|Q13439|GOGA4_HUMAN,tr|H0Y6I0|H0Y6I0_HUMAN" 2 3340.6535 2.56 107560 22941 4 3340.647248 836.1707 Golgin subfamily A member 4 OS=Homo sapiens OX=9606 GN=GOLGA4 PE=1 SV=1 4.64 3610.8 - 1.16E+06 - - - -1.8799 - 3.234 0.54 - 76.4 1 2 1 -0.0063 28 0 0 0 1.39E+07 5.42E+06 - - - 4.2888 1 221125_WJC_METTL3_EV_vs_WT_F07.22952.22952.3 3.95E-11 25/108 R.QVASHVGLHSASIPGILALDLC[160.03]PSDTNK[136.11].L "sp|Q9UMS4|PRP19_HUMAN,tr|F5GY56|F5GY56_HUMAN" 2 2907.5004 1.99 107565 22952 3 2907.50301 970.1741 Pre-mRNA-processing factor 19 OS=Homo sapiens OX=9606 GN=PRPF19 PE=1 SV=1 5.98 3612.2 - 794248 - - - 0.9004 - 4.152 0.652 - 514.4 1 2 0 0.0026 28 0 0 0 4.64E+07 2.33E+07 - - - 9.0836 1 221125_WJC_METTL3_EV_vs_WT_F07.22955.22955.4 1.63E-09 25/162 R.QVASHVGLHSASIPGILALDLC[160.03]PSDTNK.L "sp|Q9UMS4|PRP19_HUMAN,tr|F5GY56|F5GY56_HUMAN" 2 2899.4862 1.21 107566 22955 4 2899.487682 725.8788 Pre-mRNA-processing factor 19 OS=Homo sapiens OX=9606 GN=PRPF19 PE=1 SV=1 5.98 3612.6 - 1.40E+07 - - - 0.5139 - 3.75 0.603 - 307.4 1 2 0 0.0015 28 0 0 0 3.32E+08 2.74E+08 - - - 4.8845 1 221125_WJC_METTL3_EV_vs_WT_F07.22956.22956.4 1.49E-07 26/144 K.K[136.11]HISQISVAEDDDESLLGHLMIVGK[136.11].K sp|P49773|HINT1_HUMAN 1 2749.4291 2.24 107567 22956 4 2749.425243 688.3646 Adenosine 5'-monophosphoramidase HINT1 OS=Homo sapiens OX=9606 GN=HINT1 PE=1 SV=2 4.8 3612.7 - 1.27E+06 - - - -1.4141 - 2.834 0.483 - 271.4 1 2 0 -0.0039 25 0 0 0 4.32E+07 1.93E+07 - - - 3.7603 1 221125_WJC_METTL3_EV_vs_WT_F07.22957.22957.3 1.78E-10 14/96 K.EQASHLGGAVFSGAGNIAAATGLVK.R "sp|Q16143|SYUB_HUMAN,tr|G4Y816|G4Y816_HUMAN" 2 2325.2077 1.24 107568 22957 3 2325.21085 776.0765 Beta-synuclein OS=Homo sapiens OX=9606 GN=SNCB PE=1 SV=1 6.85 3612.9 - 402756 - - - 1.3508 - 3.134 0.651 - 132 1 2 0 0.0031 25 0 0 0 1.08E+07 8.73E+06 - - - 8.4252 1 221125_WJC_METTL3_EV_vs_WT_F07.22961.22961.4 4.72E-15 25/150 K.VEEQEPELTSTPNFVVEVIK[136.11]NDDGK[136.11]K[136.11].A "sp|Q07021|C1QBP_HUMAN,tr|I3L3B0|I3L3B0_HUMAN,tr|I3L3Q7|I3L3Q7_HUMAN" 3 2967.5139 1.24 107569 22961 4 2967.509413 742.8858 "Complement component 1 Q subcomponent-binding protein, mitochondrial OS=Homo sapiens OX=9606 GN=C1QBP PE=1 SV=1" 4.25 3613.4 - 4.08E+06 - - - -1.5164 - 4.11 0.697 - 400.3 1 2 1 -0.0045 26 0 0 0 1.76E+08 1.42E+08 - - - 5.7373 0.9999 221125_WJC_METTL3_EV_vs_WT_F07.22962.22962.3 5.04E-08 15/52 K.SLNNQFASFIDKVR.F sp|P04264|K2C1_HUMAN 1 1637.8526 999 107570 22962 3 1637.851465 546.9581 "Keratin, type II cytoskeletal 1 OS=Homo sapiens OX=9606 GN=KRT1 PE=1 SV=6" 8.46 3613.6 - 448455 - - - -0.6655 - 2.877 0.601 - 237.2 1 2 1 -0.0011 14 0 0 0 1.09E+07 0.00E+00 - - - 8.0486 1 221125_WJC_METTL3_EV_vs_WT_F07.22963.22963.4 1.74E-06 23/288 K.EPPAGDLAPALAEDGPPTVAPGPVQSPLPLSPLAGRPGKPGAGPAQVPR.E "sp|O95785|WIZ_HUMAN,tr|A0A669KBG4|A0A669KBG4_HUMAN,tr|A0A2R8YFV2|A0A2R8YFV2_HUMAN,tr|A0A669KAV7|A0A669KAV7_HUMAN,tr|M0QXA7|M0QXA7_HUMAN,tr|A0A669KBH9|A0A669KBH9_HUMAN,tr|B9EGQ5|B9EGQ5_HUMAN" 7 4666.4871 2.92 107571 22963 4 4666.484665 1167.6291 Protein Wiz OS=Homo sapiens OX=9606 GN=WIZ PE=1 SV=2 4.78 3613.7 - 1.53E+06 - - - -0.5272 - 2.426 0.58 - 81.7 1 2 0 -0.0025 49 0 0 0 3.82E+07 1.31E+07 - - - 4.5196 0.9995 221125_WJC_METTL3_EV_vs_WT_F07.22972.22972.3 3.71E-08 16/112 K.TQEDTSSPLSAAGQPENMDSQQLVSLVQK.A "sp|Q9Y4A5|TRRAP_HUMAN,tr|A0A2R8YFJ4|A0A2R8YFJ4_HUMAN,tr|H0Y4W2|H0Y4W2_HUMAN,tr|F2Z2U4|F2Z2U4_HUMAN" 4 3087.4666 1.57 107575 22972 3 3088.467077 1030.1628 Transformation\transcription domain-associated protein OS=Homo sapiens OX=9606 GN=TRRAP PE=1 SV=3 3.92 3614.9 - 619534 - - - 324.0323 - 3.316 0.572 - 199.4 1 2 0 1.0004 29 0 0 0 1.22E+07 7.78E+06 - - - 7.398 1 221125_WJC_METTL3_EV_vs_WT_F07.22973.22973.4 5.50E-12 31/150 K.VEEQEPELTSTPNFVVEVIKNDDGKK.A "sp|Q07021|C1QBP_HUMAN,tr|I3L3B0|I3L3B0_HUMAN,tr|I3L3Q7|I3L3Q7_HUMAN" 3 2943.4713 1.22 107576 22973 4 2943.469933 736.8751 "Complement component 1 Q subcomponent-binding protein, mitochondrial OS=Homo sapiens OX=9606 GN=C1QBP PE=1 SV=1" 4.25 3615 - 7.96E+06 - - - -0.4688 - 4.428 0.679 - 668.2 1 2 1 -0.0014 26 0 0 0 1.76E+08 1.44E+08 - - - 5.605 0.9998 221125_WJC_METTL3_EV_vs_WT_F07.22989.22989.4 1.07E-07 17/126 K.LKNFGQELAQVQHSIGQLC[160.03]NTK.D "sp|Q15643|TRIPB_HUMAN,tr|H0YJ97|H0YJ97_HUMAN" 2 2512.2856 1.38 107583 22989 4 2512.28479 629.0787 Thyroid receptor-interacting protein 11 OS=Homo sapiens OX=9606 GN=TRIP11 PE=1 SV=3 8.21 3617.2 - 659186 - - - -0.3391 - 3.552 0.483 - 248 1 2 1 -0.0009 22 0 0 0 3.08E+07 2.24E+07 - - - 3.8445 0.9995 221125_WJC_METTL3_EV_vs_WT_F07.22991.22991.4 5.53E-06 17/126 K.LK[136.11]NFGQELAQVQHSIGQLC[160.03]NTK[136.11].D "sp|Q15643|TRIPB_HUMAN,tr|H0YJ97|H0YJ97_HUMAN" 2 2528.314 1.38 107585 22991 4 2528.315426 633.0858 Thyroid receptor-interacting protein 11 OS=Homo sapiens OX=9606 GN=TRIP11 PE=1 SV=3 8.21 3617.5 - 604599 - - - 0.5474 - 3.517 0.395 - 247.6 1 2 1 0.0014 22 0 0 0 3.07E+07 2.23E+07 - - - 3.0752 0.9998 221125_WJC_METTL3_EV_vs_WT_F07.22996.22996.4 0.00258 24/156 R.SALQSINEWAAQTTDGKLPEVTKDVER.T "sp|P50454|SERPH_HUMAN,tr|E9PNX1|E9PNX1_HUMAN,tr|E9PPV6|E9PPV6_HUMAN,tr|E9PR70|E9PR70_HUMAN,tr|E9PMI5|E9PMI5_HUMAN,tr|E9PJH8|E9PJH8_HUMAN,tr|E9PK86|E9PK86_HUMAN" 7 2985.5043 1.35 107587 22996 4 2985.505113 747.3834 Serpin H1 OS=Homo sapiens OX=9606 GN=SERPINH1 PE=1 SV=2 4.51 3618.1 - 796064 - - - 0.2576 - 4.082 0.455 - 241.5 1 2 2 0.0008 27 0 0 0 4.07E+07 3.01E+07 - - - 3.6262 1 221125_WJC_METTL3_EV_vs_WT_F07.22998.22998.4 4.13E-13 30/216 R.STAPSAAASASASAAASSPAGGGAEALELLEHC[160.03]GVC[160.03]R.E sp|Q13263|TIF1B_HUMAN 1 3441.5889 1.36 107589 22998 4 3441.580715 861.4045 Transcription intermediary factor 1-beta OS=Homo sapiens OX=9606 GN=TRIM28 PE=1 SV=5 4.75 3618.3 - 593657 - - - -2.3771 - 4.747 0.625 - 305.4 1 2 0 -0.0082 37 0 0 0 3.63E+07 2.66E+07 - - - 5.1203 0.9993 221125_WJC_METTL3_EV_vs_WT_F07.23009.23009.3 4.86E-13 27/144 R.STAPSAAASASASAAASSPAGGGAEALELLEHC[160.03]GVC[160.03]R[166.11].E sp|Q13263|TIF1B_HUMAN 1 3451.5972 1.06 107595 23009 3 3452.593464 1151.5397 Transcription intermediary factor 1-beta OS=Homo sapiens OX=9606 GN=TRIM28 PE=1 SV=5 4.75 3619.8 - 825989 - - - 288.6484 - 4.866 0.517 - 543.1 1 2 0 0.9963 37 0 0 0 2.34E+07 2.21E+07 - - - 7.6683 0.9996 221125_WJC_METTL3_EV_vs_WT_F07.23015.23015.4 5.74E-10 22/156 R.SALQSINEWAAQTTDGK[136.11]LPEVTK[136.11]DVER[166.11].T "sp|P50454|SERPH_HUMAN,tr|E9PNX1|E9PNX1_HUMAN,tr|E9PPV6|E9PPV6_HUMAN,tr|E9PR70|E9PR70_HUMAN,tr|E9PMI5|E9PMI5_HUMAN,tr|E9PJH8|E9PJH8_HUMAN,tr|E9PK86|E9PK86_HUMAN" 7 3011.541 1.68 107598 23015 4 3011.536057 753.8925 Serpin H1 OS=Homo sapiens OX=9606 GN=SERPINH1 PE=1 SV=2 4.51 3620.7 - 1.06E+06 - - - -1.646 - 4.086 0.424 - 234.3 1 2 2 -0.005 27 0 0 0 4.03E+07 2.40E+07 - - - 3.3555 1 221125_WJC_METTL3_EV_vs_WT_F07.23025.23025.3 3.73E-07 40/144 R.STAPSAAASASASAAASSPAGGGAEALELLEHC[160.03]GVC[160.03]R.E sp|Q13263|TIF1B_HUMAN 1 3441.5889 1.06 107603 23025 3 3441.586399 1148.2036 Transcription intermediary factor 1-beta OS=Homo sapiens OX=9606 GN=TRIM28 PE=1 SV=5 4.75 3622 - 1.16E+06 - - - -0.7255 - 7.025 0.693 - 1617.3 1 2 0 -0.0025 37 0 0 0 2.34E+07 2.21E+07 - - - 10.7506 1 221125_WJC_METTL3_EV_vs_WT_F07.23033.23033.4 5.03E-14 34/168 K.KLGVNNISGIEEVNMFTNQGTVIHFNNPK.V "sp|P20290|BTF3_HUMAN,tr|A0A7I2V3T6|A0A7I2V3T6_HUMAN,tr|A0A7I2YQL2|A0A7I2YQL2_HUMAN" 3 3213.6241 0.85 107607 23033 4 3213.618447 804.4133 Transcription factor BTF3 OS=Homo sapiens OX=9606 GN=BTF3 PE=1 SV=1 6.76 3623 - 1.98E+06 - - - -1.7535 - 5.602 0.638 - 1023.6 1 2 0 -0.0056 29 0 0 0 2.44E+07 2.88E+07 - - - 5.3086 1 221125_WJC_METTL3_EV_vs_WT_F07.23040.23040.3 6.38E-09 16/52 K.SNSFFEGVDWEHIR.E sp|Q15208|STK38_HUMAN 1 1721.7798 33.4 107611 23040 3 1721.776875 574.9339 Serine\threonine-protein kinase 38 OS=Homo sapiens OX=9606 GN=STK38 PE=1 SV=1 4.65 3624 - 553309 - - - -1.6895 - 3.074 0.653 - 328.5 1 2 0 -0.0029 14 0 0 0 7.23E+06 2.16E+05 - - - 8.8039 1 221125_WJC_METTL3_EV_vs_WT_F07.23042.23042.3 1.91E-16 28/120 K.TPSSSQPERLPIGNTIQPSQAATFMNDAIEK.A sp|O43395|PRPF3_HUMAN 1 3327.6405 4.7 107613 23042 3 3327.628392 1110.2208 U4\U6 small nuclear ribonucleoprotein Prp3 OS=Homo sapiens OX=9606 GN=PRPF3 PE=1 SV=2 4.68 3624.2 - 851483 - - - -3.6446 - 5.795 0.726 - 538.9 1 2 1 -0.0121 31 0 0 0 2.21E+07 4.70E+06 - - - 10.673 0.999 221125_WJC_METTL3_EV_vs_WT_F07.23048.23048.3 7.25E-06 13/92 R.VETGVLK[136.11]PGMVVTFAPVNVTTEVK[136.11].S "sp|P68104|EF1A1_HUMAN,sp|Q5VTE0|EF1A3_HUMAN,tr|A0A7I2V659|A0A7I2V659_HUMAN,tr|A0A7I2V3H3|A0A7I2V3H3_HUMAN,tr|A0A7I2V5N4|A0A7I2V5N4_HUMAN,tr|A0A087WVQ9|A0A087WVQ9_HUMAN" 6 2530.4051 0.27 107617 23048 3 2530.419844 844.4757 Elongation factor 1-alpha 1 OS=Homo sapiens OX=9606 GN=EEF1A1 PE=1 SV=1 6.11 3624.9 - 484572 - - - 5.8078 - 2.643 0.494 - 124.2 1 2 0 0.0147 24 0 0 0 5.54E+06 2.04E+07 - - - 6.3009 1 221125_WJC_METTL3_EV_vs_WT_F07.23053.23053.3 4.29E-16 31/104 R.QNYVDLVSSLSPSLESSSQVEPGTDR[166.11]K[136.11].S "sp|O75521|ECI2_HUMAN,tr|F1LLU7|F1LLU7_HUMAN,tr|C9JB63|C9JB63_HUMAN,tr|F8WAW4|F8WAW4_HUMAN,tr|A0A0C4DGA2|A0A0C4DGA2_HUMAN" 5 2939.4479 0.38 107619 23053 3 2939.444735 980.8232 Enoyl-CoA delta isomerase 2 OS=Homo sapiens OX=9606 GN=ECI2 PE=1 SV=4 4.32 3625.7 - 1.30E+06 - - - -1.075 - 5.277 0.656 - 770.3 1 2 0 -0.0032 27 0 0 0 1.81E+07 4.76E+07 - - - 9.6797 0.9952 221125_WJC_METTL3_EV_vs_WT_F07.23059.23059.4 4.44E-08 19/216 R.GAGFNQNNGAGSENFGLGVVPVSASPSSVEVHPVLEK[136.11].L "sp|Q7Z739|YTHD3_HUMAN,tr|A0A087X0Q1|A0A087X0Q1_HUMAN,tr|A0A024R7W5|A0A024R7W5_HUMAN,tr|A0A087WY31|A0A087WY31_HUMAN" 4 3658.8107 -1 107623 23059 4 3659.798096 915.71 YTH domain-containing family protein 3 OS=Homo sapiens OX=9606 GN=YTHDF3 PE=1 SV=1 4.75 3626.5 - 473859 - - - 269.8669 - 3.009 0.604 - 144.8 1 2 0 0.9874 37 0 0 0 0.00E+00 0.00E+00 - - - 4.5327 1 221125_WJC_METTL3_EV_vs_WT_F07.23062.23062.4 2.72E-10 26/222 K.GILGYTEHQVVSSDFNSDTHSSTFDAGAGIALNDHFVK.L "sp|P04406|G3P_HUMAN,tr|E7EUT5|E7EUT5_HUMAN" 2 4035.8875 0.75 107624 23062 4 4035.880054 1009.9792 Glyceraldehyde-3-phosphate dehydrogenase OS=Homo sapiens OX=9606 GN=GAPDH PE=1 SV=3 4.7 3626.9 - 659324 - - - -1.8459 - 4.578 0.697 - 234.8 1 2 0 -0.0075 38 0 0 0 5.53E+07 7.38E+07 - - - 5.7342 0.9999 221125_WJC_METTL3_EV_vs_WT_F07.23066.23066.3 9.96E-08 13/92 R.NNQLDPTSKEDFLNIC[160.03]IEPDTISK.G "sp|Q53H12|AGK_HUMAN,tr|E9PC15|E9PC15_HUMAN,tr|A0A3B3ITD0|A0A3B3ITD0_HUMAN,tr|A0A3B3ISY9|A0A3B3ISY9_HUMAN,tr|A0A0G2JLG5|A0A0G2JLG5_HUMAN,tr|A0A3B3ISZ0|A0A3B3ISZ0_HUMAN" 6 2790.3382 1.36 107626 23066 3 2790.342603 931.12 "Acylglycerol kinase, mitochondrial OS=Homo sapiens OX=9606 GN=AGK PE=1 SV=2" 4.11 3627.4 - 403464 - - - 1.5815 - 2.651 0.579 - 149.5 1 2 1 0.0044 24 0 0 0 7.33E+06 5.39E+06 - - - 7.2584 0.9998 221125_WJC_METTL3_EV_vs_WT_F07.23068.23068.3 1.65E-06 13/88 K.DTNKYEGWPEVVEMEGC[160.03]IPQKQD.- sp|Q92520|FAM3C_HUMAN 1 2751.2156 1.69 107628 23068 3 2751.210402 918.0792 Protein FAM3C OS=Homo sapiens OX=9606 GN=FAM3C PE=1 SV=1 4.22 3627.7 - 349075 - - - -1.901 - 2.347 0.586 - 99.4 1 2 2 -0.0052 23 0 0 0 1.32E+07 7.81E+06 - - - 7.0733 1 221125_WJC_METTL3_EV_vs_WT_F07.23071.23071.3 4.38E-09 26/104 R.QNYVDLVSSLSPSLESSSQVEPGTDRK.S "sp|O75521|ECI2_HUMAN,tr|F1LLU7|F1LLU7_HUMAN,tr|C9JB63|C9JB63_HUMAN,tr|F8WAW4|F8WAW4_HUMAN,tr|A0A0C4DGA2|A0A0C4DGA2_HUMAN" 5 2921.4254 0.38 107630 23071 3 2921.405899 974.8158 Enoyl-CoA delta isomerase 2 OS=Homo sapiens OX=9606 GN=ECI2 PE=1 SV=4 4.32 3628 - 4.68E+06 - - - -6.6837 - 4.066 0.651 - 485 1 2 0 -0.0195 27 0 0 0 1.81E+07 4.76E+07 - - - 9.0196 0.9904 221125_WJC_METTL3_EV_vs_WT_F07.23073.23073.3 5.23E-06 15/84 L.C[160.03]LAISTPDAPATQDGVESLLQK[136.11].F "sp|Q86U44|MTA70_HUMAN,tr|B4E349|B4E349_HUMAN,tr|F5H6D8|F5H6D8_HUMAN,tr|H0YFV6|H0YFV6_HUMAN,tr|B4DTN4|B4DTN4_HUMAN" 5 2321.1664 0.02 107631 23073 3 2321.174315 774.7294 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 4.03 3628.2 - 455938 - - - 3.3983 - 3.271 0.526 - 177.1 1 1 0 0.0079 22 0 0 0 1.19E+05 7.88E+06 - - - 7.2119 1 221125_WJC_METTL3_EV_vs_WT_F07.23075.23075.4 6.84E-10 16/174 R.TTGIVMDSGDGVTHTVPIYEGYALPHAILR.L "sp|P63261|ACTG_HUMAN,sp|P60709|ACTB_HUMAN,tr|A0A804GS07|A0A804GS07_HUMAN,tr|I3L3I0|I3L3I0_HUMAN,tr|E7EVS6|E7EVS6_HUMAN,tr|A0A6Q8PFE4|A0A6Q8PFE4_HUMAN,tr|I3L1U9|I3L1U9_HUMAN,tr|A0A2R8YEA7|A0A2R8YEA7_HUMAN,tr|A0A2R8Y793|A0A2R8Y793_HUMAN,tr|I3L4N8|I3L4N8_HUMAN" 10 3182.607 0.97 107632 23075 4 3182.613902 796.659 "Actin, cytoplasmic 2 OS=Homo sapiens OX=9606 GN=ACTG1 PE=1 SV=1" 5.2 3628.5 - 480726 - - - 2.1577 - 2.981 0.644 - 91.7 1 2 0 0.0069 30 0 0 0 1.61E+07 1.67E+07 - - - 5.1637 1 221125_WJC_METTL3_EV_vs_WT_F07.23077.23077.4 4.62E-09 17/174 R.TTGIVMDSGDGVTHTVPIYEGYALPHAILR[166.11].L "sp|P63261|ACTG_HUMAN,sp|P60709|ACTB_HUMAN,tr|A0A804GS07|A0A804GS07_HUMAN,tr|I3L3I0|I3L3I0_HUMAN,tr|E7EVS6|E7EVS6_HUMAN,tr|A0A6Q8PFE4|A0A6Q8PFE4_HUMAN,tr|I3L1U9|I3L1U9_HUMAN,tr|A0A2R8YEA7|A0A2R8YEA7_HUMAN,tr|A0A2R8Y793|A0A2R8Y793_HUMAN,tr|I3L4N8|I3L4N8_HUMAN" 10 3192.6153 0.97 107633 23077 4 3192.623714 799.1611 "Actin, cytoplasmic 2 OS=Homo sapiens OX=9606 GN=ACTG1 PE=1 SV=1" 5.2 3628.7 - 704201 - - - 2.6339 - 3.098 0.638 - 111 1 2 0 0.0084 30 0 0 0 1.61E+07 1.67E+07 - - - 5.1228 0.9982 221125_WJC_METTL3_EV_vs_WT_F07.23084.23084.2 0.00012 22-Sep K.GLTPSQIGVILR.D "sp|P62277|RS13_HUMAN,tr|J3KMX5|J3KMX5_HUMAN" 2 1252.7503 999 107637 23084 2 1252.751188 627.3824 40S ribosomal protein S13 OS=Homo sapiens OX=9606 GN=RPS13 PE=1 SV=2 9.75 3629.6 - 382697 - - - 0.6913 - 1.778 0.196 - 313.1 1 2 0 0.0009 12 0 0 0 1.19E+07 0.00E+00 - - - 2.0026 0.9996 221125_WJC_METTL3_EV_vs_WT_F07.23090.23090.4 5.24E-05 11/132 R.C[160.03]KDDEFTHLYTLIVRPDNTYEVK.L "sp|P27797|CALR_HUMAN,tr|A0A7P0T861|A0A7P0T861_HUMAN,tr|K7EL50|K7EL50_HUMAN,tr|K7EJB9|K7EJB9_HUMAN" 4 2855.38 1.31 107640 23090 4 2855.388019 714.8523 Calreticulin OS=Homo sapiens OX=9606 GN=CALR PE=1 SV=1 4.83 3630.3 - 385795 - - - 2.8098 - 2.052 0.505 - 49.6 1 2 1 0.008 23 0 0 0 1.15E+07 8.79E+06 - - - 3.8522 1 221125_WJC_METTL3_EV_vs_WT_F07.23104.23104.3 1.49E-10 11/152 F.SSGGFSGGSFSRGSSGGGC[160.03]FGGSSGGYGGLGGFGGGSFR.G "sp|P13645|K1C10_HUMAN,tr|A0A1B0GVI3|A0A1B0GVI3_HUMAN" 2 3455.461 999 107647 23104 3 3456.446139 1152.8276 "Keratin, type I cytoskeletal 10 OS=Homo sapiens OX=9606 GN=KRT10 PE=1 SV=6" 9.5 3632.1 - 247033 - - - 285.0983 - 2.965 0.802 - 64.2 1 1 1 0.9851 39 0 0 0 1.04E+06 0.00E+00 - - - 9.7091 0.9992 221125_WJC_METTL3_EV_vs_WT_F07.23111.23111.4 1.41E-05 15/114 K.RIQEIIEQLDVTTSEYEKEK.L "sp|P10809|CH60_HUMAN,tr|A0A7I2V2X6|A0A7I2V2X6_HUMAN,tr|A0A7I2YQK6|A0A7I2YQK6_HUMAN,tr|A0A7I2V599|A0A7I2V599_HUMAN" 4 2450.2541 1.35 107651 23111 4 2450.26172 613.5708 "60 kDa heat shock protein, mitochondrial OS=Homo sapiens OX=9606 GN=HSPD1 PE=1 SV=2" 4.42 3633 - 423297 - - - 3.1303 - 2.855 0.46 - 109.7 1 2 1 0.0077 20 0 0 0 5.47E+07 4.06E+07 - - - 3.5784 1 221125_WJC_METTL3_EV_vs_WT_F07.23112.23112.3 6.40E-10 25/76 K.RIQEIIEQLDVTTSEYEKEK.L "sp|P10809|CH60_HUMAN,tr|A0A7I2V2X6|A0A7I2V2X6_HUMAN,tr|A0A7I2YQK6|A0A7I2YQK6_HUMAN,tr|A0A7I2V599|A0A7I2V599_HUMAN" 4 2450.2541 1.4 107652 23112 3 2450.264021 817.7586 "60 kDa heat shock protein, mitochondrial OS=Homo sapiens OX=9606 GN=HSPD1 PE=1 SV=2" 4.42 3633.1 - 467697 - - - 4.0694 - 4.828 0.595 - 926 1 2 1 0.01 20 0 0 0 1.04E+08 7.39E+07 - - - 8.9905 0.9997 221125_WJC_METTL3_EV_vs_WT_F07.23119.23119.4 1.23E-13 21/198 R.AGELDQALGR[166.11]PFTLSISNQYGDDEVTHTLQTESR[166.11].E sp|Q9BST9|RTKN_HUMAN 1 3767.8142 1.48 107654 23119 4 3768.816357 942.9608 Rhotekin OS=Homo sapiens OX=9606 GN=RTKN PE=1 SV=2 4.29 3634.1 - 341844 - - - 265.9874 - 4.603 0.646 - 193.8 1 2 0 1.0022 34 0 0 0 1.21E+07 8.18E+06 - - - 5.0265 1 221125_WJC_METTL3_EV_vs_WT_F07.23122.23122.3 3.20E-11 30/76 K.R[166.11]IQEIIEQLDVTTSEYEK[136.11]EK[136.11].L "sp|P10809|CH60_HUMAN,tr|A0A7I2V2X6|A0A7I2V2X6_HUMAN,tr|A0A7I2YQK6|A0A7I2YQK6_HUMAN,tr|A0A7I2V599|A0A7I2V599_HUMAN" 4 2476.2907 1.4 107655 23122 3 2476.292228 826.4375 "60 kDa heat shock protein, mitochondrial OS=Homo sapiens OX=9606 GN=HSPD1 PE=1 SV=2" 4.42 3634.5 - 851273 - - - 0.609 - 3.685 0.644 - 1160.8 1 2 1 0.0015 20 0 0 0 1.04E+08 7.38E+07 - - - 8.8837 1 221125_WJC_METTL3_EV_vs_WT_F07.23125.23125.4 3.11E-12 23/222 K.GILGYTEHQVVSSDFNSDTHSSTFDAGAGIALNDHFVK[136.11].L "sp|P04406|G3P_HUMAN,tr|E7EUT5|E7EUT5_HUMAN" 2 4043.9017 0.89 107657 23125 4 4044.893795 1011.9827 Glyceraldehyde-3-phosphate dehydrogenase OS=Homo sapiens OX=9606 GN=GAPDH PE=1 SV=3 4.7 3634.9 - 615634 - - - 245.3301 - 4.439 0.687 - 196.7 1 2 0 0.9921 38 0 0 0 1.92E+07 2.15E+07 - - - 5.3655 1 221125_WJC_METTL3_EV_vs_WT_F07.23126.23126.4 1.24E-09 20/114 K.R[166.11]IQEIIEQLDVTTSEYEK[136.11]EK[136.11].L "sp|P10809|CH60_HUMAN,tr|A0A7I2V2X6|A0A7I2V2X6_HUMAN,tr|A0A7I2YQK6|A0A7I2YQK6_HUMAN,tr|A0A7I2V599|A0A7I2V599_HUMAN" 4 2476.2907 1.35 107658 23126 4 2476.29417 620.08 "60 kDa heat shock protein, mitochondrial OS=Homo sapiens OX=9606 GN=HSPD1 PE=1 SV=2" 4.42 3635 - 631890 - - - 1.3932 - 3.531 0.625 - 250.4 1 2 1 0.0034 20 0 0 0 5.47E+07 4.06E+07 - - - 5.0868 1 221125_WJC_METTL3_EV_vs_WT_F07.23131.23131.4 1.23E-19 31/198 R.AGELDQALGRPFTLSISNQYGDDEVTHTLQTESR.E sp|Q9BST9|RTKN_HUMAN 1 3747.7976 1.48 107660 23131 4 3747.805618 937.9567 Rhotekin OS=Homo sapiens OX=9606 GN=RTKN PE=1 SV=2 4.29 3635.7 - 732943 - - - 2.1325 - 6.836 0.757 - 616 1 2 0 0.008 34 0 0 0 1.21E+07 8.18E+06 - - - 6.3859 1 221125_WJC_METTL3_EV_vs_WT_F07.23137.23137.4 6.74E-08 16/174 R.FHEFHSPALEDADFDNKPMVLLVGQYSTGK.T "sp|Q9NZN3|EHD3_HUMAN,sp|Q9H4M9|EHD1_HUMAN,tr|C9JC03|C9JC03_HUMAN,tr|C9JIJ3|C9JIJ3_HUMAN,tr|C9IZH1|C9IZH1_HUMAN,tr|A0A024R571|A0A024R571_HUMAN" 6 3391.6183 3.54 107663 23137 4 3391.620733 848.9119 EH domain-containing protein 3 OS=Homo sapiens OX=9606 GN=EHD3 PE=1 SV=2 4.8 3636.5 - 234803 - - - 0.7091 - 2.892 0.617 - 126.9 1 2 0 0.0024 30 0 0 0 5.03E+06 1.42E+06 - - - 4.9207 0.9997 221125_WJC_METTL3_EV_vs_WT_F07.23141.23141.3 0.000184 Oct-64 K.ELTTEIDNNIEQISSYK.S "sp|P13645|K1C10_HUMAN,tr|A0A1B0GVI3|A0A1B0GVI3_HUMAN" 2 1995.9637 999 107665 23141 3 1995.967233 666.3285 "Keratin, type I cytoskeletal 10 OS=Homo sapiens OX=9606 GN=KRT10 PE=1 SV=6" 4 3637 - 383163 - - - 1.7796 - 2.114 0.378 - 108.3 1 2 0 0.0036 17 0 0 0 1.43E+07 0.00E+00 - - - 4.6445 0.9895 221125_WJC_METTL3_EV_vs_WT_F07.23150.23150.4 3.24E-08 22/162 A.EEEDK[136.11]K[136.11]EDVGTVVGIDLGTTYSC[160.03]VGVFK[136.11].N "sp|P11021|BIP_HUMAN,tr|A0A7P0TB36|A0A7P0TB36_HUMAN,tr|A0A7P0TAI0|A0A7P0TAI0_HUMAN" 3 3097.5228 0.16 107669 23150 4 3097.528253 775.388 Endoplasmic reticulum chaperone BiP OS=Homo sapiens OX=9606 GN=HSPA5 PE=1 SV=2 4.2 3638.1 - 1.07E+06 - - - 1.7724 - 3.77 0.579 - 274.6 1 1 1 0.0055 28 0 0 0 1.80E+07 1.11E+08 - - - 4.6761 0.9436 221125_WJC_METTL3_EV_vs_WT_F07.23157.23157.4 0.000357 8/156 R.RDNYVPEVSALDQEIIEVDPDTK[136.11]EMLK[136.11].L "sp|P08708|RS17_HUMAN,tr|H3BNC9|H3BNC9_HUMAN,tr|H0YN88|H0YN88_HUMAN,tr|A0A075B716|A0A075B716_HUMAN" 4 3161.5773 - 107673 23157 4 3161.553419 791.4016 40S ribosomal protein S17 OS=Homo sapiens OX=9606 GN=RPS17 PE=1 SV=2 4.07 3639 - 492025 - - - -7.557 - 2.087 0.383 - 24 1 2 1 -0.0239 27 0 0 0 - - - - - 2.7832 1 221125_WJC_METTL3_EV_vs_WT_F07.23161.23161.4 2.81E-10 20/120 S.LHTDGDK[136.11]AFVDFLSDEIK[136.11]EER[166.11].K sp|Q07021|C1QBP_HUMAN 1 2489.2285 1.2 107675 23161 4 2489.233046 623.3144 "Complement component 1 Q subcomponent-binding protein, mitochondrial OS=Homo sapiens OX=9606 GN=C1QBP PE=1 SV=1" 4.38 3639.5 - 328086 - - - 1.8447 - 4.037 0.65 - 277.6 1 1 2 0.0046 21 0 0 0 1.73E+08 1.44E+08 - - - 5.3437 0.9999 221125_WJC_METTL3_EV_vs_WT_F07.23162.23162.3 7.19E-09 14/64 K.AAIDWFDGK[136.11]EFSGNPIK[136.11].V "sp|P35637|FUS_HUMAN,tr|H3BPE7|H3BPE7_HUMAN" 2 1909.9545 1.55 107676 23162 3 1909.956513 637.6588 RNA-binding protein FUS OS=Homo sapiens OX=9606 GN=FUS PE=1 SV=1 4.56 3639.6 - 297392 - - - 1.0466 - 3.312 0.576 - 239 1 2 1 0.002 17 0 0 0 1.33E+07 8.55E+06 - - - 7.9867 1 221125_WJC_METTL3_EV_vs_WT_F07.23167.23167.4 6.86E-11 23/120 S.LHTDGDKAFVDFLSDEIKEER.K sp|Q07021|C1QBP_HUMAN 1 2463.1918 1.2 107679 23167 4 2463.195906 616.8052 "Complement component 1 Q subcomponent-binding protein, mitochondrial OS=Homo sapiens OX=9606 GN=C1QBP PE=1 SV=1" 4.38 3640.2 - 862091 - - - 1.6734 - 3.848 0.64 - 439.5 1 1 2 0.0041 21 0 0 0 1.73E+08 1.44E+08 - - - 5.241 1 221125_WJC_METTL3_EV_vs_WT_F07.23168.23168.3 2.97E-09 20/128 R.AAC[160.03]EQLHQQQQQQQEETAAATLLLQGEEEGEED.- sp|Q00577|PURA_HUMAN 1 3738.6551 - 107680 23168 3 3738.657662 1247.2257 Transcriptional activator protein Pur-alpha OS=Homo sapiens OX=9606 GN=PURA PE=1 SV=2 3.81 3640.4 - 505440 - - - 0.6797 - 4.428 0.662 - 373.1 1 2 0 0.0025 33 0 0 0 - - - - - 9.3432 0.888 221125_WJC_METTL3_EV_vs_WT_F07.23169.23169.4 2.08E-07 25/162 A.EEEDKKEDVGTVVGIDLGTTYSC[160.03]VGVFK.N "sp|P11021|BIP_HUMAN,tr|A0A7P0TB36|A0A7P0TB36_HUMAN,tr|A0A7P0TAI0|A0A7P0TAI0_HUMAN" 3 3073.4802 0.17 107681 23169 4 3073.494983 769.3773 Endoplasmic reticulum chaperone BiP OS=Homo sapiens OX=9606 GN=HSPA5 PE=1 SV=2 4.2 3640.4 - 1.29E+06 - - - 4.8219 - 3.179 0.544 - 226.9 1 1 1 0.0148 28 0 0 0 1.84E+07 1.11E+08 - - - 4.316 0.9999 221125_WJC_METTL3_EV_vs_WT_F07.23174.23174.4 0.00107 9/108 R.GLLQDDAHPTLVTYADHSK[136.11].L "sp|Q86U44|MTA70_HUMAN,tr|F5H6D8|F5H6D8_HUMAN,tr|H0YFV6|H0YFV6_HUMAN,tr|B4DTN4|B4DTN4_HUMAN" 4 2088.0367 0 107685 23174 4 2088.037624 523.0165 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 5.13 3641.2 - 246602 - - - 0.4267 - 2.048 0.466 - 79.8 1 2 0 0.0009 19 0 0 0 2.90E+04 1.66E+07 - - - 3.5243 1 221125_WJC_METTL3_EV_vs_WT_F07.23176.23176.3 8.59E-14 20/108 A.EEEDK[136.11]K[136.11]EDVGTVVGIDLGTTYSC[160.03]VGVFK[136.11].N "sp|P11021|BIP_HUMAN,tr|A0A7P0TB36|A0A7P0TB36_HUMAN,tr|A0A7P0TAI0|A0A7P0TAI0_HUMAN" 3 3097.5228 0.2 107686 23176 3 3097.52085 1033.5149 Endoplasmic reticulum chaperone BiP OS=Homo sapiens OX=9606 GN=HSPA5 PE=1 SV=2 4.2 3641.4 - 640478 - - - -0.6176 - 4.177 0.678 - 348.2 1 1 1 -0.0019 28 0 0 0 2.37E+06 1.18E+07 - - - 9.3875 1 221125_WJC_METTL3_EV_vs_WT_F07.23180.23180.4 0.0385 23/192 R.AAC[160.03]EQLHQQQQQQQEETAAATLLLQGEEEGEED.- sp|Q00577|PURA_HUMAN 1 3738.6551 - 107689 23180 4 3738.651597 935.6711 Transcriptional activator protein Pur-alpha OS=Homo sapiens OX=9606 GN=PURA PE=1 SV=2 3.81 3641.9 - 605676 - - - -0.9426 - 4.799 0.566 - 275.4 1 2 0 -0.0035 33 0 0 0 - - - - - 4.6221 0.9999 221125_WJC_METTL3_EV_vs_WT_F07.23187.23187.4 1.91E-06 17/138 K.NELHNLLDKPQLQGIPVLVLGNKR.D "sp|Q96BM9|ARL8A_HUMAN,sp|Q9NVJ2|ARL8B_HUMAN" 2 2707.5497 1.23 107693 23187 4 2707.561907 677.8947 ADP-ribosylation factor-like protein 8A OS=Homo sapiens OX=9606 GN=ARL8A PE=1 SV=1 8.6 3642.7 - 306861 - - - 4.5015 - 3.277 0.59 - 222.5 1 2 0 0.0122 24 0 0 0 7.43E+07 6.03E+07 - - - 4.7389 1 221125_WJC_METTL3_EV_vs_WT_F07.23191.23191.3 7.84E-15 22/80 S.LHTDGDK[136.11]AFVDFLSDEIK[136.11]EER[166.11].K sp|Q07021|C1QBP_HUMAN 1 2489.2285 1.37 107695 23191 3 2489.226057 830.7501 "Complement component 1 Q subcomponent-binding protein, mitochondrial OS=Homo sapiens OX=9606 GN=C1QBP PE=1 SV=1" 4.38 3643.3 - 496108 - - - -0.9629 - 4.177 0.705 - 496.4 1 1 2 -0.0024 21 0 0 0 2.77E+07 2.02E+07 - - - 9.8268 1 221125_WJC_METTL3_EV_vs_WT_F07.23196.23196.4 6.56E-09 21/138 K.NELHNLLDK[136.11]PQLQGIPVLVLGNK[136.11]R[166.11].D "sp|Q96BM9|ARL8A_HUMAN,sp|Q9NVJ2|ARL8B_HUMAN" 2 2733.5864 1.23 107697 23196 4 2733.588301 684.4039 ADP-ribosylation factor-like protein 8A OS=Homo sapiens OX=9606 GN=ARL8A PE=1 SV=1 8.6 3643.9 - 509080 - - - 0.6994 - 3.807 0.671 - 259.8 1 2 0 0.0019 24 0 0 0 7.43E+07 6.03E+07 - - - 5.4949 0.9996 221125_WJC_METTL3_EV_vs_WT_F07.23203.23203.4 1.56E-05 14/120 K.HK[136.11]GSPFPEVAESVQQELESYR[166.11].A "sp|Q8WVM8|SCFD1_HUMAN,tr|A0A7I2V4U2|A0A7I2V4U2_HUMAN,tr|A0A7I2V4B8|A0A7I2V4B8_HUMAN,tr|H0YIZ7|H0YIZ7_HUMAN,tr|A0A7I2V5Z4|A0A7I2V5Z4_HUMAN,tr|A0A7I2V3C9|A0A7I2V3C9_HUMAN,tr|B7Z5N7|B7Z5N7_HUMAN,tr|A0A7I2V5I2|A0A7I2V5I2_HUMAN,tr|A0A7I2V590|A0A7I2V590_HUMAN,tr|G3V5E2|G3V5E2_HUMAN,tr|A0A7I2V2U5|A0A7I2V2U5_HUMAN,tr|A0A7I2YQR2|A0A7I2YQR2_HUMAN,tr|A0A7I2V362|A0A7I2V362_HUMAN,tr|A0A7I2V448|A0A7I2V448_HUMAN,tr|A0A7I2V320|A0A7I2V320_HUMAN,tr|A0A7I2V534|A0A7I2V534_HUMAN,tr|A0A7I2V3G4|A0A7I2V3G4_HUMAN,tr|A0A7I2V3B4|A0A7I2V3B4_HUMAN,tr|A0A7I2V5H5|A0A7I2V5H5_HUMAN,tr|A0A7I2V4R0|A0A7I2V4R0_HUMAN" 20 2434.1884 1.27 107702 23203 4 2434.192151 609.5544 Sec1 family domain-containing protein 1 OS=Homo sapiens OX=9606 GN=SCFD1 PE=1 SV=4 4.91 3644.8 - 409323 - - - 1.5521 - 2.859 0.437 - 108.5 1 2 1 0.0038 21 0 0 0 1.43E+07 1.13E+07 - - - 3.3759 1 221125_WJC_METTL3_EV_vs_WT_F07.23206.23206.3 4.77E-08 14/128 R.AQAETGPTSFPSPVSVSMK[136.11]PDLPVSLPTQTAPK[136.11].Q sp|Q96T58|MINT_HUMAN 1 3380.7509 1.67 107703 23206 3 3380.750801 1127.9242 Msx2-interacting protein OS=Homo sapiens OX=9606 GN=SPEN PE=1 SV=1 6.11 3645.2 - 348987 - - - -0.0172 - 2.787 0.653 - 92.3 1 2 0 -0.0001 33 0 0 0 1.07E+07 6.39E+06 - - - 8.1784 1 221125_WJC_METTL3_EV_vs_WT_F07.23208.23208.3 2.95E-07 10/120 R.GQYQGLSQDPNSLSNLDQDLPNNMIHQVPIK[136.11].S sp|Q9NYU2|UGGG1_HUMAN 1 3470.698 0.04 107705 23208 3 3470.695397 1157.9066 UDP-glucose:glycoprotein glucosyltransferase 1 OS=Homo sapiens OX=9606 GN=UGGT1 PE=1 SV=3 4.41 3645.5 - 330620 - - - -0.7448 - 2.407 0.612 - 69.1 1 2 0 -0.0026 31 0 0 0 1.70E+06 4.06E+07 - - - 7.3833 1 221125_WJC_METTL3_EV_vs_WT_F07.23209.23209.4 5.15E-07 20/138 R.AEVQHQLHVAVGSLQESILAQVQR[166.11].L "sp|Q6P2E9|EDC4_HUMAN,tr|I3L3M2|I3L3M2_HUMAN" 2 2649.4226 0.92 107706 23209 4 2649.423807 663.3629 Enhancer of mRNA-decapping protein 4 OS=Homo sapiens OX=9606 GN=EDC4 PE=1 SV=1 6.01 3645.6 - 306865 - - - 0.4492 - 3.592 0.48 - 264.5 1 2 0 0.0012 24 0 0 0 6.93E+06 7.51E+06 - - - 3.814 1 221125_WJC_METTL3_EV_vs_WT_F07.23212.23212.4 3.05E-08 19/180 R.GQYQGLSQDPNSLSNLDQDLPNNMIHQVPIK[136.11].S sp|Q9NYU2|UGGG1_HUMAN 1 3470.698 0.05 107707 23212 4 3470.697194 868.6818 UDP-glucose:glycoprotein glucosyltransferase 1 OS=Homo sapiens OX=9606 GN=UGGT1 PE=1 SV=3 4.41 3646 - 648890 - - - -0.227 - 2.773 0.588 - 149.5 1 2 0 -0.0008 31 0 0 0 2.51E+06 4.76E+07 - - - 4.6537 0.9997 221125_WJC_METTL3_EV_vs_WT_F07.23213.23213.4 0.000405 14/192 R.AQAETGPTSFPSPVSVSMKPDLPVSLPTQTAPK.Q sp|Q96T58|MINT_HUMAN 1 3364.7225 4.97 107708 23213 4 3364.731533 842.1879 Msx2-interacting protein OS=Homo sapiens OX=9606 GN=SPEN PE=1 SV=1 6.11 3646.1 - 435529 - - - 2.6968 - 2.841 0.42 - 50.4 1 2 0 0.0091 33 0 0 0 1.11E+07 2.23E+06 - - - 3.1924 1 221125_WJC_METTL3_EV_vs_WT_F07.23214.23214.4 1.35E-08 17/138 R.AEVQHQLHVAVGSLQESILAQVQR.L "sp|Q6P2E9|EDC4_HUMAN,tr|I3L3M2|I3L3M2_HUMAN" 2 2639.4143 0.92 107709 23214 4 2639.417944 660.8609 Enhancer of mRNA-decapping protein 4 OS=Homo sapiens OX=9606 GN=EDC4 PE=1 SV=1 6.01 3646.3 - 400138 - - - 1.3628 - 3.296 0.564 - 200.9 1 2 0 0.0036 24 0 0 0 6.93E+06 7.51E+06 - - - 4.5169 0.9998 221125_WJC_METTL3_EV_vs_WT_F07.23224.23224.4 2.87E-09 15/120 K.HKGSPFPEVAESVQQELESYR.A "sp|Q8WVM8|SCFD1_HUMAN,tr|A0A7I2V4U2|A0A7I2V4U2_HUMAN,tr|A0A7I2V4B8|A0A7I2V4B8_HUMAN,tr|H0YIZ7|H0YIZ7_HUMAN,tr|A0A7I2V5Z4|A0A7I2V5Z4_HUMAN,tr|A0A7I2V3C9|A0A7I2V3C9_HUMAN,tr|B7Z5N7|B7Z5N7_HUMAN,tr|A0A7I2V5I2|A0A7I2V5I2_HUMAN,tr|A0A7I2V590|A0A7I2V590_HUMAN,tr|G3V5E2|G3V5E2_HUMAN,tr|A0A7I2V2U5|A0A7I2V2U5_HUMAN,tr|A0A7I2YQR2|A0A7I2YQR2_HUMAN,tr|A0A7I2V362|A0A7I2V362_HUMAN,tr|A0A7I2V448|A0A7I2V448_HUMAN,tr|A0A7I2V320|A0A7I2V320_HUMAN,tr|A0A7I2V534|A0A7I2V534_HUMAN,tr|A0A7I2V3G4|A0A7I2V3G4_HUMAN,tr|A0A7I2V3B4|A0A7I2V3B4_HUMAN,tr|A0A7I2V5H5|A0A7I2V5H5_HUMAN,tr|A0A7I2V4R0|A0A7I2V4R0_HUMAN" 20 2416.1659 1.27 107715 23224 4 2416.172206 605.0488 Sec1 family domain-containing protein 1 OS=Homo sapiens OX=9606 GN=SCFD1 PE=1 SV=4 4.91 3647.6 - 415318 - - - 2.6087 - 2.919 0.566 - 163.2 1 2 1 0.0063 21 0 0 0 1.43E+07 1.13E+07 - - - 4.5049 0.9999 221125_WJC_METTL3_EV_vs_WT_F07.23258.23258.4 6.48E-08 25/144 K.GTTGTQASFLQLFEGDDHKVEQLDK.M "sp|P30566|PUR8_HUMAN,tr|A0A096LNY5|A0A096LNY5_HUMAN,tr|A0A1B0GTJ7|A0A1B0GTJ7_HUMAN,tr|A0A1B0GWJ0|A0A1B0GWJ0_HUMAN,tr|A0A1B0GWF8|A0A1B0GWF8_HUMAN,tr|A0A1B0GTG9|A0A1B0GTG9_HUMAN,tr|A0A0A6YY92|A0A0A6YY92_HUMAN,tr|A0A7P0T8E4|A0A7P0T8E4_HUMAN,tr|A0A7P0T9A7|A0A7P0T9A7_HUMAN,tr|A0A096LNY6|A0A096LNY6_HUMAN,tr|A0A096LPA2|A0A096LPA2_HUMAN,tr|A0A096LP92|A0A096LP92_HUMAN,tr|A0A7P0Z472|A0A7P0Z472_HUMAN" 13 2763.3352 0.63 107729 23258 4 2763.338172 691.8411 Adenylosuccinate lyase OS=Homo sapiens OX=9606 GN=ADSL PE=1 SV=2 4.43 3652.2 - 679315 - - - 1.0922 - 4.487 0.579 - 453.6 1 2 1 0.003 25 0 0 0 5.37E+07 8.57E+07 - - - 4.7423 1 221125_WJC_METTL3_EV_vs_WT_F07.23264.23264.4 1.27E-12 31/168 K.TAVIDHHNYDISDLGQHTLIVADTENLLK.A "sp|P39656|OST48_HUMAN,tr|U3KQ84|U3KQ84_HUMAN,tr|A0A0C4DGS1|A0A0C4DGS1_HUMAN" 3 3244.6364 1.24 107733 23264 4 3244.644227 812.1664 Dolichyl-diphosphooligosaccharide--protein glycosyltransferase 48 kDa subunit OS=Homo sapiens OX=9606 GN=DDOST PE=1 SV=4 4.7 3653 - 982253 - - - 2.4058 - 4.923 0.698 - 601.6 1 2 0 0.0078 29 0 0 0 1.17E+08 9.41E+07 - - - 5.7905 0.9868 221125_WJC_METTL3_EV_vs_WT_F07.23266.23266.3 3.64E-05 18/104 R.RDNYVPEVSALDQEIIEVDPDTK[136.11]EMLK[136.11].L "sp|P08708|RS17_HUMAN,tr|H3BNC9|H3BNC9_HUMAN,tr|H0YN88|H0YN88_HUMAN,tr|A0A075B716|A0A075B716_HUMAN" 4 3161.5773 - 107735 23266 3 3161.549491 1054.8664 40S ribosomal protein S17 OS=Homo sapiens OX=9606 GN=RPS17 PE=1 SV=2 4.07 3653.3 - 652140 - - - -8.7994 - 3.252 0.511 - 182.4 1 2 1 -0.0278 27 0 0 0 - - - - - 6.9425 1 221125_WJC_METTL3_EV_vs_WT_F07.23274.23274.4 2.23E-15 34/168 K.TAVIDHHNYDISDLGQHTLIVADTENLLK[136.11].A "sp|P39656|OST48_HUMAN,tr|U3KQ84|U3KQ84_HUMAN,tr|A0A0C4DGS1|A0A0C4DGS1_HUMAN" 3 3252.6506 1.24 107737 23274 4 3252.65031 814.1699 Dolichyl-diphosphooligosaccharide--protein glycosyltransferase 48 kDa subunit OS=Homo sapiens OX=9606 GN=DDOST PE=1 SV=4 4.7 3654.4 - 2.12E+06 - - - -0.0956 - 5.505 0.706 - 761.6 1 2 0 -0.0003 29 0 0 0 1.17E+08 9.41E+07 - - - 5.8966 1 221125_WJC_METTL3_EV_vs_WT_F07.23286.23286.4 1.05E-13 42/210 R.HVGDLGNVTADK[136.11]DGVADVSIEDSVISLSGDHC[160.03]IIGR[166.11].T "sp|P00441|SODC_HUMAN,tr|H7BYH4|H7BYH4_HUMAN" 2 3737.8286 3.31 107741 23286 4 3737.831811 935.4644 Superoxide dismutase [Cu-Zn] OS=Homo sapiens OX=9606 GN=SOD1 PE=1 SV=2 4.27 3656.2 - 834271 - - - 0.8719 - 7.099 0.716 - 1054 1 2 1 0.0033 36 0 0 0 1.50E+08 4.54E+07 - - - 6.0349 0.999 221125_WJC_METTL3_EV_vs_WT_F07.23287.23287.3 0.0094 Sep-96 K.GTTGTQASFLQLFEGDDHKVEQLDK.M "sp|P30566|PUR8_HUMAN,tr|A0A096LNY5|A0A096LNY5_HUMAN,tr|A0A1B0GTJ7|A0A1B0GTJ7_HUMAN,tr|A0A1B0GWJ0|A0A1B0GWJ0_HUMAN,tr|A0A1B0GWF8|A0A1B0GWF8_HUMAN,tr|A0A1B0GTG9|A0A1B0GTG9_HUMAN,tr|A0A0A6YY92|A0A0A6YY92_HUMAN,tr|A0A7P0T8E4|A0A7P0T8E4_HUMAN,tr|A0A7P0T9A7|A0A7P0T9A7_HUMAN,tr|A0A096LNY6|A0A096LNY6_HUMAN,tr|A0A096LPA2|A0A096LPA2_HUMAN,tr|A0A096LP92|A0A096LP92_HUMAN,tr|A0A7P0Z472|A0A7P0Z472_HUMAN" 13 2763.3352 0.03 107742 23287 3 2763.340123 922.119 Adenylosuccinate lyase OS=Homo sapiens OX=9606 GN=ADSL PE=1 SV=2 4.43 3656.3 - 252396 - - - 1.7982 - 2.49 0.386 - 53.8 1 2 1 0.005 25 0 0 0 3.29E+06 1.18E+08 - - - 4.941 1 221125_WJC_METTL3_EV_vs_WT_F07.23292.23292.4 2.31E-11 21/132 K.KLSELSNSQQSVQTLSLWLIHHR.K "sp|Q96P16|RPR1A_HUMAN,sp|Q9NQG5|RPR1B_HUMAN,tr|E9PIQ9|E9PIQ9_HUMAN,tr|E9PQF3|E9PQF3_HUMAN,tr|A0A0C4DGQ6|A0A0C4DGQ6_HUMAN,tr|K7EQR8|K7EQR8_HUMAN" 6 2703.4456 2.18 107744 23292 4 2703.446067 676.8687 Regulation of nuclear pre-mRNA domain-containing protein 1A OS=Homo sapiens OX=9606 GN=RPRD1A PE=1 SV=1 8.76 3657 - 778088 - - - 0.1554 - 4.186 0.624 - 341.3 1 2 0 0.0004 23 0 0 0 1.38E+07 6.31E+06 - - - 5.121 0.9994 221125_WJC_METTL3_EV_vs_WT_F07.23299.23299.2 1.57E-09 13/26 K.LISWYDNEFGYSNR[166.11].V "sp|P04406|G3P_HUMAN,tr|E7EUT5|E7EUT5_HUMAN" 2 1772.8034 1.56 107746 23299 2 1772.796739 887.409 Glyceraldehyde-3-phosphate dehydrogenase OS=Homo sapiens OX=9606 GN=GAPDH PE=1 SV=3 4.37 3658.1 - 562927 - - - -3.7404 - 2.66 0.569 - 649.3 1 2 0 -0.0066 14 0 0 0 3.28E+07 2.10E+07 - - - 5.6966 1 221125_WJC_METTL3_EV_vs_WT_F07.23302.23302.2 5.44E-09 13/26 K.LISWYDNEFGYSNR.V "sp|P04406|G3P_HUMAN,tr|E7EUT5|E7EUT5_HUMAN" 2 1762.7951 1.71 107748 23302 2 1762.790719 882.4048 Glyceraldehyde-3-phosphate dehydrogenase OS=Homo sapiens OX=9606 GN=GAPDH PE=1 SV=3 4.37 3658.5 - 473696 - - - -2.4853 - 2.778 0.683 - 659.2 1 2 0 -0.0044 14 0 0 0 3.63E+07 2.12E+07 - - - 6.6482 0.9999 221125_WJC_METTL3_EV_vs_WT_F07.23303.23303.4 3.91E-09 16/132 K.K[136.11]LSELSNSQQSVQTLSLWLIHHR[166.11].K "sp|Q96P16|RPR1A_HUMAN,sp|Q9NQG5|RPR1B_HUMAN,tr|E9PIQ9|E9PIQ9_HUMAN,tr|E9PQF3|E9PQF3_HUMAN,tr|A0A0C4DGQ6|A0A0C4DGQ6_HUMAN,tr|K7EQR8|K7EQR8_HUMAN" 6 2721.4681 2.37 107749 23303 4 2721.456577 681.3743 Regulation of nuclear pre-mRNA domain-containing protein 1A OS=Homo sapiens OX=9606 GN=RPRD1A PE=1 SV=1 8.76 3658.6 - 321039 - - - -4.2404 - 2.809 0.592 - 140.7 1 2 0 -0.0115 23 0 0 0 1.51E+07 6.38E+06 - - - 4.7102 0.9996 221125_WJC_METTL3_EV_vs_WT_F07.23307.23307.2 0.00883 22-Sep K.DAGVIAGLNVLR[166.11].L "sp|P0DMV8|HS71A_HUMAN,sp|P34931|HS71L_HUMAN,sp|P0DMV9|HS71B_HUMAN,tr|Q53FA3|Q53FA3_HUMAN,tr|A0A0G2JIW1|A0A0G2JIW1_HUMAN" 5 1206.696 0.11 107751 23307 2 1206.696602 604.3553 Heat shock 70 kDa protein 1A OS=Homo sapiens OX=9606 GN=HSPA1A PE=1 SV=1 5.84 3659.1 - 354277 - - - 0.5063 - 1.822 0.355 - 247.1 1 2 0 0.0006 12 0 0 0 2.35E+06 2.12E+07 - - - 3.2414 1 221125_WJC_METTL3_EV_vs_WT_F07.23323.23323.4 3.06E-13 31/174 K.EQELNQSISEKETLIAEIEELDRQNQEATK.H "sp|Q15643|TRIPB_HUMAN,tr|H0YJ97|H0YJ97_HUMAN" 2 3514.7275 1.12 107757 23323 4 3514.731952 879.6891 Thyroid receptor-interacting protein 11 OS=Homo sapiens OX=9606 GN=TRIP11 PE=1 SV=3 4.14 3661.4 - 1.34E+06 - - - 1.2721 - 5.47 0.663 - 567.8 1 2 2 0.0045 30 0 0 0 1.65E+08 1.48E+08 - - - 5.5155 0.9999 221125_WJC_METTL3_EV_vs_WT_F07.23329.23329.4 1.39E-09 21/132 K.RVNKEESLQMQVQDILEQNEALK.A sp|Q86UP2|KTN1_HUMAN 1 2741.4018 2.25 107759 23329 4 2741.406736 686.3577 Kinectin OS=Homo sapiens OX=9606 GN=KTN1 PE=1 SV=1 4.59 3662.3 - 745795 - - - 1.8031 - 4.13 0.581 - 308.8 1 2 1 0.0049 23 0 0 0 1.77E+07 7.85E+06 - - - 4.7412 0.9999 221125_WJC_METTL3_EV_vs_WT_F07.23340.23340.4 1.79E-08 17/132 K.R[166.11]VNK[136.11]EESLQMQVQDILEQNEALK[136.11].A sp|Q86UP2|KTN1_HUMAN 1 2767.4385 2.23 107765 23340 4 2767.442129 692.8669 Kinectin OS=Homo sapiens OX=9606 GN=KTN1 PE=1 SV=1 4.59 3663.7 - 515584 - - - 1.3247 - 3.608 0.559 - 221.6 1 2 1 0.0037 23 0 0 0 1.75E+07 7.85E+06 - - - 4.5062 0.9999 221125_WJC_METTL3_EV_vs_WT_F07.23344.23344.4 9.83E-10 30/174 K.EQELNQSISEK[136.11]ETLIAEIEELDR[166.11]QNQEATK[136.11].H "sp|Q15643|TRIPB_HUMAN,tr|H0YJ97|H0YJ97_HUMAN" 2 3540.7642 1.11 107767 23344 4 3540.761661 886.1983 Thyroid receptor-interacting protein 11 OS=Homo sapiens OX=9606 GN=TRIP11 PE=1 SV=3 4.14 3664.2 - 6.28E+06 - - - -0.7032 - 5.333 0.599 - 473.3 1 2 2 -0.0025 30 0 0 0 1.65E+08 1.48E+08 - - - 4.9512 0.9999 221125_WJC_METTL3_EV_vs_WT_F07.23345.23345.4 7.06E-09 18/102 R.RNEQDFYAAVDDFRNEFK.V sp|Q9H8V3|ECT2_HUMAN 1 2263.0294 1.45 107768 23345 4 2263.031408 566.7646 Protein ECT2 OS=Homo sapiens OX=9606 GN=ECT2 PE=1 SV=4 4.44 3664.3 - 608826 - - - 0.8829 - 2.552 0.629 - 78.3 1 2 1 0.002 18 0 0 0 9.23E+06 6.37E+06 - - - 5.0212 0.9488 221125_WJC_METTL3_EV_vs_WT_F07.23346.23346.4 2.23E-06 19/156 R.GFGFVTFADPASVDKVLGQPHHELDSK.T "sp|Q96DH6|MSI2H_HUMAN,tr|B4DHE8|B4DHE8_HUMAN,tr|A0A6Q8PF05|A0A6Q8PF05_HUMAN,tr|J3QKT5|J3QKT5_HUMAN,tr|A0A6Q8PFU8|A0A6Q8PFU8_HUMAN,tr|J3KTC1|J3KTC1_HUMAN,tr|A0A6Q8PHT3|A0A6Q8PHT3_HUMAN" 7 2897.4348 0.92 107769 23346 4 2898.450894 725.366 RNA-binding protein Musashi homolog 2 OS=Homo sapiens OX=9606 GN=MSI2 PE=1 SV=1 5.26 3664.4 - 608378 - - - 350.6847 - 2.729 0.506 - 153.9 1 2 1 1.0161 27 0 0 0 7.11E+06 7.71E+06 - - - 3.6629 1 221125_WJC_METTL3_EV_vs_WT_F07.23368.23368.4 1.42E-14 28/228 W.GVYPASLFQQQAAAAAAATNSANQQTTPQAQQGQQQVLR.G "sp|Q14671|PUM1_HUMAN,tr|Q5T1Z8|Q5T1Z8_HUMAN,tr|H0YDK8|H0YDK8_HUMAN,tr|H0YEH2|H0YEH2_HUMAN,tr|Q5T1Z4|Q5T1Z4_HUMAN,tr|H0YED4|H0YED4_HUMAN,tr|E9PR38|E9PR38_HUMAN" 7 4041.0053 2.33 107781 23368 4 4041.011157 1011.2586 Pumilio homolog 1 OS=Homo sapiens OX=9606 GN=PUM1 PE=1 SV=3 8.75 3667.2 - 1.25E+06 - - - 1.4573 - 5.413 0.648 - 289.9 1 1 0 0.0059 39 0 0 0 3.98E+07 1.71E+07 - - - 5.3545 0.9956 221125_WJC_METTL3_EV_vs_WT_F07.23383.23383.4 9.95E-06 23/180 A.QAQAFLGHLHQVQLAGTSLQAAAQSLNVQSK[136.11].S "sp|P14859|PO2F1_HUMAN,tr|A0A0A0MT46|A0A0A0MT46_HUMAN" 2 3251.7255 2.06 107790 23383 4 3251.72619 813.9386 "POU domain, class 2, transcription factor 1 OS=Homo sapiens OX=9606 GN=POU2F1 PE=1 SV=2" 8.76 3669.1 - 935640 - - - 0.2251 - 3.999 0.486 - 264.8 1 1 0 0.0007 31 0 0 0 7.15E+07 3.47E+07 - - - 3.8772 0.9967 221125_WJC_METTL3_EV_vs_WT_F07.23386.23386.4 3.30E-09 26/180 A.QAQAFLGHLHQVQLAGTSLQAAAQSLNVQSK.S "sp|P14859|PO2F1_HUMAN,tr|A0A0A0MT46|A0A0A0MT46_HUMAN" 2 3243.7113 2.07 107791 23386 4 3243.713435 811.9351 "POU domain, class 2, transcription factor 1 OS=Homo sapiens OX=9606 GN=POU2F1 PE=1 SV=2" 8.76 3669.5 - 1.50E+06 - - - 0.6711 - 4.186 0.512 - 483.5 1 1 0 0.0022 31 0 0 0 7.18E+07 3.47E+07 - - - 4.117 1 221125_WJC_METTL3_EV_vs_WT_F07.23387.23387.4 2.04E-10 20/228 R.TPQNFSVPSPGPLNTPVNPSSVMSPAGSSQAEEQQYLDK.L "sp|Q96RN5|MED15_HUMAN,tr|G3V1P5|G3V1P5_HUMAN" 2 4084.9324 2 107792 23387 4 4084.935798 1022.2404 Mediator of RNA polymerase II transcription subunit 15 OS=Homo sapiens OX=9606 GN=MED15 PE=1 SV=2 4.14 3669.6 - 714067 - - - 0.8306 - 3.876 0.518 - 199.5 1 2 0 0.0034 39 0 0 0 1.05E+07 5.24E+06 - - - 4.1268 0.9999 221125_WJC_METTL3_EV_vs_WT_F07.23397.23397.4 5.86E-06 10/120 K.FENAFLSHVVSQHQALLGTIR.A sp|P25705|ATPA_HUMAN 1 2366.2495 0.21 107796 23397 4 2366.250489 592.5697 "ATP synthase subunit alpha, mitochondrial OS=Homo sapiens OX=9606 GN=ATP5F1A PE=1 SV=1" 6.92 3671.1 - 354984 - - - 0.412 - 1.86 0.464 - 48 1 2 0 0.001 21 0 0 0 6.10E+06 2.85E+07 - - - 3.4696 1 221125_WJC_METTL3_EV_vs_WT_F07.23410.23410.3 3.38E-08 20/68 R.C[160.03]QHAAHIISELILTAQER.D sp|Q96I24|FUBP3_HUMAN 1 2089.0739 2.34 107801 23410 3 2089.076858 697.3652 Far upstream element-binding protein 3 OS=Homo sapiens OX=9606 GN=FUBP3 PE=1 SV=2 6 3672.8 - 220561 - - - 1.436 - 3.843 0.582 - 640.4 1 2 0 0.003 18 0 0 0 4.67E+07 2.00E+07 - - - 8.3802 0.9545 221125_WJC_METTL3_EV_vs_WT_F07.23423.23423.3 0.759 15/76 K.FEAHPNDLYVEGLPENIPFR.S "sp|P78347|GTF2I_HUMAN,tr|A0A494C0Q7|A0A494C0Q7_HUMAN,tr|A0A494C1K3|A0A494C1K3_HUMAN" 3 2356.1488 1.94 107807 23423 3 2356.147718 786.3902 General transcription factor II-I OS=Homo sapiens OX=9606 GN=GTF2I PE=1 SV=2 4.4 3674.2 - 827034 - - - -0.458 - 1.322 0.152 - 60 1 2 0 -0.0011 20 0 0 0 1.77E+07 9.12E+06 - - - 0.9116 0.9988 221125_WJC_METTL3_EV_vs_WT_F07.23424.23424.3 3.36E-05 Dec-68 K.YVHYEIDAC[160.03]MDSEAPGSK[136.11].D "sp|Q86U44|MTA70_HUMAN,tr|H0YFV6|H0YFV6_HUMAN" 2 2078.8805 0.01 107808 23424 3 2079.881135 693.9674 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 4.31 3674.4 - 191069 - - - 481.3374 - 2.008 0.568 - 147.8 1 2 0 1.0006 18 0 0 0 2.19E+05 1.68E+07 - - - 6.3314 1 221125_WJC_METTL3_EV_vs_WT_F07.23429.23429.4 2.52E-07 28/174 K.ETFHDIAQVASEFPGAQHYVGGNAALIGQK.F "sp|Q9BRR6|ADPGK_HUMAN,tr|H3BRS6|H3BRS6_HUMAN,tr|H3BU35|H3BU35_HUMAN" 3 3154.5472 1 107810 23429 4 3154.554163 789.6441 ADP-dependent glucokinase OS=Homo sapiens OX=9606 GN=ADPGK PE=1 SV=1 5.28 3675 - 771667 - - - 2.2035 - 4.362 0.605 - 367.2 1 2 0 0.007 30 0 0 0 1.53E+07 1.53E+07 - - - 4.9407 0.9997 221125_WJC_METTL3_EV_vs_WT_F07.23437.23437.4 6.49E-08 18/102 R.C[160.03]QHAAHIISELILTAQER.D sp|Q96I24|FUBP3_HUMAN 1 2089.0739 1.53 107813 23437 4 2089.081177 523.2757 Far upstream element-binding protein 3 OS=Homo sapiens OX=9606 GN=FUBP3 PE=1 SV=2 6 3676 - 303194 - - - 3.5035 - 3.242 0.43 - 292.7 1 2 0 0.0073 18 0 0 0 2.39E+07 1.57E+07 - - - 3.3696 1 221125_WJC_METTL3_EV_vs_WT_F07.23442.23442.3 1.55E-09 19/76 R.HQNQNTIQELLQNC[160.03]SDC[160.03]LMR.A "sp|P15924|DESP_HUMAN,tr|A0A804HL18|A0A804HL18_HUMAN" 2 2501.121 999 107814 23442 3 2501.119775 834.7143 Desmoplakin OS=Homo sapiens OX=9606 GN=DSP PE=1 SV=3 5.32 3676.8 - 523160 - - - -0.4742 - 4.143 0.659 - 638.1 1 2 0 -0.0012 20 0 0 0 1.59E+07 0.00E+00 - - - 9.3353 1 221125_WJC_METTL3_EV_vs_WT_F07.23444.23444.4 0.000165 18/102 R.C[160.03]QHAAHIISELILTAQER[166.11].D sp|Q96I24|FUBP3_HUMAN 1 2099.0821 1.51 107815 23444 4 2099.078556 525.7778 Far upstream element-binding protein 3 OS=Homo sapiens OX=9606 GN=FUBP3 PE=1 SV=2 6 3677 - 247467 - - - -1.7017 - 3.273 0.481 - 299.7 1 2 0 -0.0036 18 0 0 0 2.40E+07 1.59E+07 - - - 3.8178 1 221125_WJC_METTL3_EV_vs_WT_F07.23446.23446.4 1.48E-13 23/174 K.ETFHDIAQVASEFPGAQHYVGGNAALIGQK[136.11].F "sp|Q9BRR6|ADPGK_HUMAN,tr|H3BRS6|H3BRS6_HUMAN,tr|H3BU35|H3BU35_HUMAN" 3 3162.5614 1.02 107816 23446 4 3162.559671 791.6476 ADP-dependent glucokinase OS=Homo sapiens OX=9606 GN=ADPGK PE=1 SV=1 5.28 3677.2 - 564800 - - - -0.5505 - 4.805 0.68 - 295.4 1 2 0 -0.0017 30 0 0 0 1.53E+07 1.51E+07 - - - 5.6246 0.9968 221125_WJC_METTL3_EV_vs_WT_F07.23456.23456.3 4.90E-06 14/72 L.TLGNQLDGIHLLDPDVVAR[166.11].F sp|Q86U44|MTA70_HUMAN 1 2055.0988 0.02 107819 23456 3 2055.101927 686.0402 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 4.41 3678.6 - 445807 - - - 1.5104 - 2.298 0.572 - 132.4 1 1 0 0.0031 19 0 0 0 2.73E+05 1.24E+07 - - - 6.9605 0.997 221125_WJC_METTL3_EV_vs_WT_F07.23472.23472.4 0.000186 20/150 R.K[136.11]IELFGR[166.11]PHNVQPNWITLGNQLDGIH.L sp|Q86U44|MTA70_HUMAN 1 3013.6005 0 107826 23472 4 3013.599722 754.4074 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 6.92 3680.6 - 943211 - - - -0.2678 - 3.775 0.524 - 196.4 1 1 0 -0.0008 26 0 0 0 2.68E+05 6.10E+07 - - - 4.2057 1 221125_WJC_METTL3_EV_vs_WT_F07.23486.23486.3 0.000163 20/60 K.K[136.11]VSQEILELLNTTTAK[136.11].E "sp|Q86U44|MTA70_HUMAN,tr|H0YFV6|H0YFV6_HUMAN" 2 1803.0324 0.03 107831 23486 3 1803.032818 602.0181 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 6.14 3682.5 - 2.09E+06 - - - 0.2152 - 4.103 0.648 - 826.9 1 2 0 0.0004 16 0 0 0 1.34E+08 4.06E+09 - - - 9.3867 1 221125_WJC_METTL3_EV_vs_WT_F07.23492.23492.2 6.53E-05 20/30 K.K[136.11]VSQEILELLNTTTAK[136.11].E "sp|Q86U44|MTA70_HUMAN,tr|H0YFV6|H0YFV6_HUMAN" 2 1803.0324 0.001 107833 23492 2 1803.030821 902.5235 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 6.14 3683.4 - 594016 - - - -0.8924 - 3.61 0.606 - 1097.7 1 2 0 -0.0016 16 0 0 0 0.00E+00 5.91E+08 - - - 6.6725 1 221125_WJC_METTL3_EV_vs_WT_F07.23499.23499.4 8.26E-13 27/282 R.DSAGVPAPAPDSALDSAPTPASAPAPAPALAQAPALSPSLASAPEEAK.S sp|Q7Z2T5|TRM1L_HUMAN 1 4400.2024 0.88 107837 23499 4 4400.201754 1101.0579 TRMT1-like protein OS=Homo sapiens OX=9606 GN=TRMT1L PE=1 SV=2 3.77 3684.3 - 1.52E+06 - - - -0.1368 - 4.433 0.643 - 224.1 1 2 0 -0.0006 48 0 0 0 1.72E+07 1.96E+07 - - - 5.2374 1 221125_WJC_METTL3_EV_vs_WT_F07.23510.23510.4 7.07E-12 20/150 K.QKEFTDNVSSAFEQDDFEEAKEILTK.M sp|Q8IWL3|HSC20_HUMAN 1 3047.4248 3.75 107843 23510 4 3047.434593 762.8635 Iron-sulfur cluster co-chaperone protein HscB OS=Homo sapiens OX=9606 GN=HSCB PE=1 SV=3 4.12 3685.8 - 693871 - - - 3.2276 - 4.526 0.648 - 286 1 2 2 0.0098 26 0 0 0 2.21E+07 5.88E+06 - - - 5.3397 0.9979 221125_WJC_METTL3_EV_vs_WT_F07.23528.23528.4 5.74E-05 19/168 K.HAVSDPSILDSLDLNEDER[166.11]EVLINNINR[166.11]R[166.11].L "sp|P05198|IF2A_HUMAN,tr|H0YJS4|H0YJS4_HUMAN,tr|G3V4T5|G3V4T5_HUMAN" 3 3375.7161 0.94 107852 23528 4 3375.704993 844.9363 Eukaryotic translation initiation factor 2 subunit 1 OS=Homo sapiens OX=9606 GN=EIF2S1 PE=1 SV=3 4.38 3688.1 - 818922 - - - -3.2962 - 3.083 0.395 - 110.4 1 2 1 -0.0111 29 0 0 0 9.36E+07 9.95E+07 - - - 3.008 0.9999 221125_WJC_METTL3_EV_vs_WT_F07.23534.23534.3 1.02E-06 16/92 K.QTQTFTTYSDNQPGVLIQVYEGER[166.11].A "sp|P11142|HSP7C_HUMAN,tr|E9PNE6|E9PNE6_HUMAN,tr|A8K7Q2|A8K7Q2_HUMAN,tr|E9PKE3|E9PKE3_HUMAN,tr|E9PS65|E9PS65_HUMAN" 5 2783.3278 0.1 107855 23534 3 2783.319825 928.7832 Heat shock cognate 71 kDa protein OS=Homo sapiens OX=9606 GN=HSPA8 PE=1 SV=1 4.14 3688.9 - 719187 - - - -2.8559 - 3.026 0.536 - 226 1 2 0 -0.0079 24 0 0 0 5.30E+06 5.27E+07 - - - 7.0853 0.9999 221125_WJC_METTL3_EV_vs_WT_F07.23541.23541.4 2.42E-09 28/168 K.HAVSDPSILDSLDLNEDEREVLINNINRR.L "sp|P05198|IF2A_HUMAN,tr|H0YJS4|H0YJS4_HUMAN,tr|G3V4T5|G3V4T5_HUMAN" 3 3345.6913 0.94 107858 23541 4 3345.690063 837.4301 Eukaryotic translation initiation factor 2 subunit 1 OS=Homo sapiens OX=9606 GN=EIF2S1 PE=1 SV=3 4.38 3689.8 - 1.36E+06 - - - -0.3727 - 3.924 0.555 - 248.2 1 2 1 -0.0012 29 0 0 0 9.36E+07 9.95E+07 - - - 4.4777 0.9993 221125_WJC_METTL3_EV_vs_WT_F07.23551.23551.2 1.43E-06 13/30 K.KVSQEILELLNTTTAK[136.11].E "sp|Q86U44|MTA70_HUMAN,tr|H0YFV6|H0YFV6_HUMAN" 2 1795.0182 - 107862 23551 2 1795.011498 898.5164 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 6.14 3691.2 - 498992 - - - -3.7504 - 2.786 0.51 - 353.7 1 2 0 -0.0067 16 0 0 0 - - - - - 5.3248 1 221125_WJC_METTL3_EV_vs_WT_F07.23562.23562.3 1.90E-07 14/60 K.K[136.11]VSQEILELLNTTTAK.E "sp|Q86U44|MTA70_HUMAN,tr|H0YFV6|H0YFV6_HUMAN" 2 1795.0182 - 107866 23562 3 1795.017419 599.3467 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 6.14 3692.8 - 3.90E+06 - - - -0.4518 - 3.149 0.529 - 331.9 2 2 0 -0.0008 16 0 0 0 - - - - - 7.2415 0.9996 221125_WJC_METTL3_EV_vs_WT_F07.23569.23569.4 0.000616 24/132 K.HLEIFHTEFQNLLDADK[136.11]NEDLGR[166.11].M "sp|Q13616|CUL1_HUMAN,tr|A0A590UJA0|A0A590UJA0_HUMAN,tr|A0A0C4DGX4|A0A0C4DGX4_HUMAN,tr|A0A590UJ21|A0A590UJ21_HUMAN,tr|A0A590UJ50|A0A590UJ50_HUMAN,tr|A0A590UJR3|A0A590UJR3_HUMAN,tr|A0A590UJ56|A0A590UJ56_HUMAN,tr|A0A590UK34|A0A590UK34_HUMAN" 8 2771.3634 1.03 107869 23569 4 2771.359464 693.8481 Cullin-1 OS=Homo sapiens OX=9606 GN=CUL1 PE=1 SV=2 4.57 3693.7 - 421519 - - - -1.4123 - 2.727 0.424 - 137 1 2 1 -0.0039 23 0 0 0 2.36E+07 2.29E+07 - - - 3.2404 0.9998 221125_WJC_METTL3_EV_vs_WT_F07.23582.23582.4 2.30E-09 24/162 R.AKNPTDKPVIGISTYNIVPFEAGQYFNK.L "sp|Q9Y6N1|COX11_HUMAN,tr|I3L4E7|I3L4E7_HUMAN,tr|B4DI26|B4DI26_HUMAN" 3 3110.6077 1.37 107877 23582 4 3110.597657 778.6592 "Cytochrome c oxidase assembly protein COX11, mitochondrial OS=Homo sapiens OX=9606 GN=COX11 PE=1 SV=3" 8.42 3695.5 - 1.06E+06 - - - -3.2245 - 3.659 0.59 - 302.7 1 2 1 -0.01 28 0 0 0 3.28E+07 2.40E+07 - - - 4.7613 1 221125_WJC_METTL3_EV_vs_WT_F07.23588.23588.4 2.90E-17 36/174 R.HIADLAGNSEVILPVPAFNVINGGSHAGNK.L "sp|P06733|ENOA_HUMAN,tr|A0A2R8Y6G6|A0A2R8Y6G6_HUMAN,tr|K7EM90|K7EM90_HUMAN,tr|A0A2R8YEM5|A0A2R8YEM5_HUMAN" 4 3010.5625 1.58 107880 23588 4 3010.567766 753.6479 Alpha-enolase OS=Homo sapiens OX=9606 GN=ENO1 PE=1 SV=2 5.99 3696.3 - 897626 - - - 1.7598 - 5.673 0.659 - 743.3 1 2 0 0.0053 30 0 0 0 1.26E+09 7.99E+08 - - - 5.4916 0.9956 221125_WJC_METTL3_EV_vs_WT_F07.23590.23590.3 1.87E-05 13/80 R.KDIENQYETQITQIEHEVSSS.G "sp|P35527|K1C9_HUMAN,tr|K7EQQ3|K7EQQ3_HUMAN" 2 2477.1558 121.55 107882 23590 3 2477.151523 826.7259 "Keratin, type I cytoskeletal 9 OS=Homo sapiens OX=9606 GN=KRT9 PE=1 SV=3" 4.25 3696.6 - 505539 - - - -1.7233 - 2.514 0.524 - 109.7 1 1 0 -0.0043 21 0 0 0 1.50E+07 1.23E+05 - - - 6.5911 1 221125_WJC_METTL3_EV_vs_WT_F07.23595.23595.4 4.58E-20 52/198 K.LHEEEIQELQAQIQEQHVQIDVDVSKPDLTAALR.D "sp|P08670|VIME_HUMAN,tr|B0YJC5|B0YJC5_HUMAN,tr|B0YJC4|B0YJC4_HUMAN" 3 3922.0072 2.28 107884 23595 4 3922.010923 981.5091 Vimentin OS=Homo sapiens OX=9606 GN=VIM PE=1 SV=4 4.32 3697.2 - 2.21E+06 - - - 0.9429 - 6.005 0.724 - 963.2 1 2 0 0.0037 34 0 0 0 1.28E+08 5.60E+07 - - - 6.0612 0.9978 221125_WJC_METTL3_EV_vs_WT_F07.23601.23601.4 0.00571 Sep-90 K.DLHEGFHYIIHELTQK.T sp|Q8IW75|SPA12_HUMAN 1 1978.9901 286.07 107888 23601 4 1978.992379 495.7548 Serpin A12 OS=Homo sapiens OX=9606 GN=SERPINA12 PE=1 SV=1 5.75 3697.9 - 306462 - - - 1.146 - 1.704 0.266 - 49.2 1 2 0 0.0023 16 0 0 0 1.61E+07 5.63E+04 - - - 1.7284 0.8974 221125_WJC_METTL3_EV_vs_WT_F07.23603.23603.4 0.00839 9/108 R.GLLQDDAHPTLVTYADHSK[136.11].L "sp|Q86U44|MTA70_HUMAN,tr|F5H6D8|F5H6D8_HUMAN,tr|H0YFV6|H0YFV6_HUMAN,tr|B4DTN4|B4DTN4_HUMAN" 4 2088.0367 0.001 107890 23603 4 2089.034742 523.0165 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 5.13 3698.2 - 188786 - - - 477.9653 - 1.933 0.308 - 59 1 2 0 0.998 19 0 0 0 0.00E+00 8.84E+06 - - - 1.8533 0.9993 221125_WJC_METTL3_EV_vs_WT_F07.23607.23607.4 5.70E-06 24/150 R.SFGTEDRPTDRPIPPRDEVFEYIIFR.G "sp|Q8ND56|LS14A_HUMAN,tr|I3L4Q1|I3L4Q1_HUMAN,tr|A0A140TA76|A0A140TA76_HUMAN,tr|K7EMZ9|K7EMZ9_HUMAN" 4 3151.5727 1 107892 23607 4 3151.584878 788.9005 Protein LSM14 homolog A OS=Homo sapiens OX=9606 GN=LSM14A PE=1 SV=3 4.59 3698.6 - 6.37E+06 - - - 3.8644 - 2.809 0.52 - 91.3 1 2 1 0.0122 26 0 0 0 1.56E+09 1.56E+09 - - - 4.0745 1 221125_WJC_METTL3_EV_vs_WT_F07.23610.23610.4 1.03E-18 41/198 K.LHEEEIQELQAQIQEQHVQIDVDVSK[136.11]PDLTAALR[166.11].D "sp|P08670|VIME_HUMAN,tr|B0YJC5|B0YJC5_HUMAN,tr|B0YJC4|B0YJC4_HUMAN" 3 3940.0297 2.28 107893 23610 4 3940.032131 986.0147 Vimentin OS=Homo sapiens OX=9606 GN=VIM PE=1 SV=4 4.32 3699 - 1.68E+06 - - - 0.6183 - 6.241 0.678 - 600.1 1 2 0 0.0024 34 0 0 0 1.28E+08 5.60E+07 - - - 5.6727 0.9997 221125_WJC_METTL3_EV_vs_WT_F07.23613.23613.4 5.98E-11 17/102 R.SHTEEDC[160.03]TEELFDFLHAR[166.11].D sp|P07919|QCR6_HUMAN 1 2244.9621 1.26 107896 23613 4 2245.963602 562.2478 "Cytochrome b-c1 complex subunit 6, mitochondrial OS=Homo sapiens OX=9606 GN=UQCRH PE=1 SV=2" 4.35 3699.4 - 211417 - - - 446.0966 - 2.969 0.64 - 337.8 1 2 0 1.0015 18 0 0 0 1.71E+07 1.35E+07 - - - 4.8919 1 221125_WJC_METTL3_EV_vs_WT_F07.23618.23618.4 4.37E-09 23/102 R.SHTEEDC[160.03]TEELFDFLHAR.D sp|P07919|QCR6_HUMAN 1 2234.9539 1.29 107897 23618 4 2234.955432 559.7457 "Cytochrome b-c1 complex subunit 6, mitochondrial OS=Homo sapiens OX=9606 GN=UQCRH PE=1 SV=2" 4.35 3700.2 - 354161 - - - 0.7025 - 4.115 0.723 - 668.6 1 2 0 0.0016 18 0 0 0 1.71E+07 1.32E+07 - - - 6.0032 0.9898 221125_WJC_METTL3_EV_vs_WT_F07.23621.23621.3 0.00318 6/100 R.SFGTEDRPTDRPIPPRDEVFEYIIFR.G "sp|Q8ND56|LS14A_HUMAN,tr|I3L4Q1|I3L4Q1_HUMAN,tr|A0A140TA76|A0A140TA76_HUMAN,tr|K7EMZ9|K7EMZ9_HUMAN" 4 3151.5727 1.41 107898 23621 3 3151.57206 1051.5315 Protein LSM14 homolog A OS=Homo sapiens OX=9606 GN=LSM14A PE=1 SV=3 4.59 3700.6 - 639037 - - - -0.2028 - 1.114 0.356 - 10.1 1 2 1 -0.0006 26 0 0 0 4.76E+07 3.38E+07 - - - 2.7572 1 221125_WJC_METTL3_EV_vs_WT_F07.23623.23623.3 5.85E-13 35/116 R.HIADLAGNSEVILPVPAFNVINGGSHAGNK.L "sp|P06733|ENOA_HUMAN,tr|A0A2R8Y6G6|A0A2R8Y6G6_HUMAN,tr|K7EM90|K7EM90_HUMAN,tr|A0A2R8YEM5|A0A2R8YEM5_HUMAN" 4 3010.5625 1.68 107899 23623 3 3010.562587 1004.5281 Alpha-enolase OS=Homo sapiens OX=9606 GN=ENO1 PE=1 SV=2 5.99 3700.8 - 900679 - - - 0.0395 - 5.695 0.724 - 1426.4 1 2 0 0.0001 30 0 0 0 1.46E+08 8.70E+07 - - - 10.614 1 221125_WJC_METTL3_EV_vs_WT_F07.23630.23630.3 3.18E-13 27/116 R.HIADLAGNSEVILPVPAFNVINGGSHAGNK[136.11].L "sp|P06733|ENOA_HUMAN,tr|A0A2R8Y6G6|A0A2R8Y6G6_HUMAN,tr|K7EM90|K7EM90_HUMAN,tr|A0A2R8YEM5|A0A2R8YEM5_HUMAN" 4 3018.5767 1.68 107902 23630 3 3018.574361 1007.1995 Alpha-enolase OS=Homo sapiens OX=9606 GN=ENO1 PE=1 SV=2 5.99 3701.6 - 964633 - - - -0.7643 - 4.947 0.617 - 575.1 1 2 0 -0.0023 30 0 0 0 1.46E+08 8.70E+07 - - - 9.0965 1 221125_WJC_METTL3_EV_vs_WT_F07.23636.23636.3 1.03E-10 24/136 F.GSKPAPGTLGTGLGAGFGTALGAGQASLFGNNQPK.L "sp|P52948|NUP98_HUMAN,tr|A0A3B3ITD8|A0A3B3ITD8_HUMAN,tr|H0YEN4|H0YEN4_HUMAN" 3 3198.6422 2.75 107905 23636 3 3198.639868 1067.2213 Nuclear pore complex protein Nup98-Nup96 OS=Homo sapiens OX=9606 GN=NUP98 PE=1 SV=4 10 3702.4 - 1.04E+06 - - - -0.7212 - 4.54 0.673 - 505 1 1 0 -0.0023 35 0 0 0 4.03E+07 1.47E+07 - - - 9.5233 1 221125_WJC_METTL3_EV_vs_WT_F07.23656.23656.3 3.39E-07 21/136 F.GSK[136.11]PAPGTLGTGLGAGFGTALGAGQASLFGNNQPK[136.11].L "sp|P52948|NUP98_HUMAN,tr|A0A3B3ITD8|A0A3B3ITD8_HUMAN,tr|H0YEN4|H0YEN4_HUMAN" 3 3214.6706 2.75 107912 23656 3 3214.672343 1072.5641 Nuclear pore complex protein Nup98-Nup96 OS=Homo sapiens OX=9606 GN=NUP98 PE=1 SV=4 10 3705 - 1.03E+06 - - - 0.55 - 3.384 0.651 - 200.3 1 1 0 0.0018 35 0 0 0 4.03E+07 1.47E+07 - - - 8.6021 1 221125_WJC_METTL3_EV_vs_WT_F07.23661.23661.3 3.45E-07 25/52 K.KQELEEILHDLESR.V sp|P35580|MYH10_HUMAN 1 1737.8897 0.77 107914 23661 3 1737.888702 580.3039 Myosin-10 OS=Homo sapiens OX=9606 GN=MYH10 PE=1 SV=3 4.57 3705.6 - 1.37E+06 - - - -0.5904 - 4.539 0.564 - 1281.7 1 2 0 -0.001 14 0 0 0 4.57E+07 5.94E+07 - - - 8.8478 1 221125_WJC_METTL3_EV_vs_WT_F07.23667.23667.3 4.66E-19 25/96 R.EQELHNLLEVVSQC[160.03]C[160.03]EASSSDITEK.S "sp|P52732|KIF11_HUMAN,tr|A0A7I2V3A9|A0A7I2V3A9_HUMAN" 2 2904.3117 4.39 107918 23667 3 2904.309147 969.1112 Kinesin-like protein KIF11 OS=Homo sapiens OX=9606 GN=KIF11 PE=1 SV=2 4.14 3706.4 - 1.10E+07 - - - -0.8852 - 4.665 0.777 - 839.2 1 2 0 -0.0026 25 0 0 0 1.62E+09 3.69E+08 - - - 10.7453 1 221125_WJC_METTL3_EV_vs_WT_F07.23670.23670.2 2.03E-11 19/32 L.PVPAFNVINGGSHAGNK.L "sp|P13929|ENOB_HUMAN,sp|P06733|ENOA_HUMAN,sp|P09104|ENOG_HUMAN,tr|A0A2R8Y6G6|A0A2R8Y6G6_HUMAN,tr|K7EM90|K7EM90_HUMAN,tr|E5RGZ4|E5RGZ4_HUMAN,tr|A0A2R8YEM5|A0A2R8YEM5_HUMAN,tr|K7EPM1|K7EPM1_HUMAN,tr|K7EKN2|K7EKN2_HUMAN" 9 1677.8587 6.05 107921 23670 2 1677.848161 839.9366 Beta-enolase OS=Homo sapiens OX=9606 GN=ENO3 PE=1 SV=5 9.18 3706.8 - 501570 - - - -6.283 - 2.927 0.685 - 1165.1 1 1 0 -0.0105 17 0 0 0 1.37E+07 2.27E+06 - - - 6.7375 0.9993 221125_WJC_METTL3_EV_vs_WT_F07.23675.23675.4 2.51E-06 15/78 K.K[136.11]QELEEILHDLESR[166.11].V sp|P35580|MYH10_HUMAN 1 1755.9122 1.11 107923 23675 4 1755.908733 439.9853 Myosin-10 OS=Homo sapiens OX=9606 GN=MYH10 PE=1 SV=3 4.57 3707.5 - 154681 - - - -1.9733 - 2.953 0.318 - 274.3 1 2 0 -0.0035 14 0 0 0 9.70E+06 8.73E+06 - - - 2.387 0.9999 221125_WJC_METTL3_EV_vs_WT_F07.23677.23677.4 0.000147 16/78 K.KQELEEILHDLESR.V sp|P35580|MYH10_HUMAN 1 1737.8897 1.11 107924 23677 4 1737.886591 435.4797 Myosin-10 OS=Homo sapiens OX=9606 GN=MYH10 PE=1 SV=3 4.57 3707.7 - 358496 - - - -1.8051 - 2.492 0.447 - 163.2 1 2 0 -0.0031 14 0 0 0 9.70E+06 8.73E+06 - - - 3.4481 1 221125_WJC_METTL3_EV_vs_WT_F07.23679.23679.4 7.81E-17 27/144 R.EQELHNLLEVVSQC[160.03]C[160.03]EASSSDITEK.S "sp|P52732|KIF11_HUMAN,tr|A0A7I2V3A9|A0A7I2V3A9_HUMAN" 2 2904.3117 4.77 107925 23679 4 2904.312867 727.0852 Kinesin-like protein KIF11 OS=Homo sapiens OX=9606 GN=KIF11 PE=1 SV=2 4.14 3707.9 - 9.53E+06 - - - 0.3956 - 4.508 0.755 - 547.3 1 2 0 0.0011 25 0 0 0 2.94E+08 6.17E+07 - - - 6.2762 1 221125_WJC_METTL3_EV_vs_WT_F07.23681.23681.3 6.73E-13 30/104 R.SSGTASSVAFTPLQGLEIVNPQAAEKK.V "sp|Q8WWY3|PRP31_HUMAN,tr|E7EVX8|E7EVX8_HUMAN" 2 2729.4236 2.49 107926 23681 3 2729.422296 910.8151 U4\U6 small nuclear ribonucleoprotein Prp31 OS=Homo sapiens OX=9606 GN=PRPF31 PE=1 SV=2 5.86 3708.1 - 1.93E+06 - - - -0.4686 - 5.243 0.65 - 1036.2 1 2 0 -0.0013 27 0 0 0 1.70E+08 6.84E+07 - - - 9.5984 1 221125_WJC_METTL3_EV_vs_WT_F07.23683.23683.4 5.18E-08 21/216 K.K[136.11]PGAGDTAFPGTGGFSATFDYQQAFGNSTGGFDGQAR[166.11].Q sp|Q96PK6|RBM14_HUMAN 1 3702.673 1.7 107927 23683 4 3702.669524 926.6755 RNA-binding protein 14 OS=Homo sapiens OX=9606 GN=RBM14 PE=1 SV=2 4.43 3708.4 - 711368 - - - -0.949 - 4.06 0.564 - 130.4 1 2 0 -0.0035 37 0 0 0 1.82E+08 1.07E+08 - - - 4.5449 1 221125_WJC_METTL3_EV_vs_WT_F07.23687.23687.3 1.92E-15 26/104 R.SSGTASSVAFTPLQGLEIVNPQAAEK[136.11]K[136.11].V "sp|Q8WWY3|PRP31_HUMAN,tr|E7EVX8|E7EVX8_HUMAN" 2 2745.452 2.49 107929 23687 3 2745.447181 916.1579 U4\U6 small nuclear ribonucleoprotein Prp31 OS=Homo sapiens OX=9606 GN=PRPF31 PE=1 SV=2 5.86 3708.8 - 984075 - - - -1.7462 - 4.459 0.754 - 734 1 2 0 -0.0048 27 0 0 0 1.70E+08 6.84E+07 - - - 10.3843 1 221125_WJC_METTL3_EV_vs_WT_F07.23694.23694.3 2.11E-16 30/144 K.KPGAGDTAFPGTGGFSATFDYQQAFGNSTGGFDGQAR.Q sp|Q96PK6|RBM14_HUMAN 1 3684.6506 2.2 107933 23694 3 3684.64818 1229.2241 RNA-binding protein 14 OS=Homo sapiens OX=9606 GN=RBM14 PE=1 SV=2 4.43 3709.7 - 1.48E+06 - - - -0.6481 - 5.225 0.748 - 560.1 1 2 0 -0.0024 37 0 0 0 1.85E+08 8.41E+07 - - - 10.6828 1 221125_WJC_METTL3_EV_vs_WT_F07.23696.23696.4 3.69E-12 37/216 K.KPGAGDTAFPGTGGFSATFDYQQAFGNSTGGFDGQAR.Q sp|Q96PK6|RBM14_HUMAN 1 3684.6506 1.7 107934 23696 4 3684.648666 922.1699 RNA-binding protein 14 OS=Homo sapiens OX=9606 GN=RBM14 PE=1 SV=2 4.43 3709.9 - 2.46E+06 - - - -0.5162 - 5.262 0.648 - 434 1 2 0 -0.0019 37 0 0 0 1.85E+08 1.09E+08 - - - 5.3525 0.9994 221125_WJC_METTL3_EV_vs_WT_F07.23705.23705.4 0.000148 15/108 R.GMQDLVEDFKNKYEDEINK.R sp|P02538|K2C6A_HUMAN 1 2314.0787 999 107940 23705 4 2314.081248 579.527 "Keratin, type II cytoskeletal 6A OS=Homo sapiens OX=9606 GN=KRT6A PE=1 SV=3" 4.3 3711 - 728449 - - - 1.089 - 2.223 0.403 - 183.4 1 2 2 0.0025 19 0 0 0 1.70E+07 0.00E+00 - - - 3.0033 1 221125_WJC_METTL3_EV_vs_WT_F07.23706.23706.3 5.27E-18 30/144 K.K[136.11]PGAGDTAFPGTGGFSATFDYQQAFGNSTGGFDGQAR[166.11].Q sp|Q96PK6|RBM14_HUMAN 1 3702.673 2.2 107941 23706 3 3702.66651 1235.2316 RNA-binding protein 14 OS=Homo sapiens OX=9606 GN=RBM14 PE=1 SV=2 4.43 3711.1 - 1.22E+06 - - - -1.7631 - 5.102 0.746 - 517.2 1 2 0 -0.0065 37 0 0 0 1.85E+08 8.41E+07 - - - 10.6045 0.9999 221125_WJC_METTL3_EV_vs_WT_F07.23711.23711.4 8.50E-07 22/138 K.QC[160.03]ANLQNAIADAEQRGELALKDAR.N "sp|P13647|K2C5_HUMAN,tr|H0YI76|H0YI76_HUMAN" 2 2654.3195 58.96 107944 23711 4 2654.321322 664.5871 "Keratin, type II cytoskeletal 5 OS=Homo sapiens OX=9606 GN=KRT5 PE=1 SV=3" 4.78 3711.8 - 968743 - - - 0.7011 - 2.931 0.53 - 240.2 1 2 2 0.0019 24 0 0 0 3.27E+07 5.55E+05 - - - 4.1838 0.9999 221125_WJC_METTL3_EV_vs_WT_F07.23716.23716.4 1.21E-10 24/168 R.EHPWEVMPDLYFYR[166.11]DPEEIEK[136.11]EEQAAAEK[136.11].A "sp|P08865|RSSA_HUMAN,tr|C9J9K3|C9J9K3_HUMAN,tr|A0A0C4DG17|A0A0C4DG17_HUMAN" 3 3603.6714 0.5 107946 23716 4 3603.664524 901.9251 40S ribosomal protein SA OS=Homo sapiens OX=9606 GN=RPSA PE=1 SV=4 4.22 3712.4 - 1.30E+06 - - - -1.918 - 3.989 0.596 - 181.9 1 2 2 -0.0069 29 0 0 0 1.32E+07 2.62E+07 - - - 4.8381 1 221125_WJC_METTL3_EV_vs_WT_F07.23724.23724.3 0.000164 14/60 K.K[136.11]VSQEILELLNTTTAK[136.11].E "sp|Q86U44|MTA70_HUMAN,tr|H0YFV6|H0YFV6_HUMAN" 2 1803.0324 0.03 107950 23724 3 1803.033181 602.0181 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 6.14 3713.3 - 332868 - - - 0.4165 - 3.316 0.611 - 394.4 1 2 0 0.0008 16 0 0 0 1.41E+08 4.06E+09 - - - 8.4277 1 221125_WJC_METTL3_EV_vs_WT_F07.23738.23738.4 1.88E-11 27/180 R.KEEQEVQATLESEEVDLNAGLHGNWTLENAK.A sp|Q08211|DHX9_HUMAN 1 3480.6645 1.07 107956 23738 4 3480.658278 871.1734 ATP-dependent RNA helicase A OS=Homo sapiens OX=9606 GN=DHX9 PE=1 SV=4 4.21 3715.2 - 570526 - - - -1.7836 - 5.723 0.674 - 506.6 1 2 0 -0.0062 31 0 0 0 1.00E+08 9.39E+07 - - - 5.621 0.9997 221125_WJC_METTL3_EV_vs_WT_F07.23747.23747.3 5.18E-05 Sep-64 K.KSEIQTLKEEIEQSLTK.R "sp|Q14258|TRI25_HUMAN,tr|A0A3B3IUA7|A0A3B3IUA7_HUMAN" 2 2003.0787 2.18 107960 23747 3 2003.07927 668.7002 E3 ubiquitin\ISG15 ligase TRIM25 OS=Homo sapiens OX=9606 GN=TRIM25 PE=1 SV=2 4.95 3716.5 - 181723 - - - 0.309 - 2.387 0.448 - 88.7 1 2 1 0.0006 17 0 0 0 9.72E+06 4.46E+06 - - - 5.7326 1 221125_WJC_METTL3_EV_vs_WT_F07.23751.23751.4 1.71E-12 35/180 R.K[136.11]EEQEVQATLESEEVDLNAGLHGNWTLENAK[136.11].A sp|Q08211|DHX9_HUMAN 1 3496.6929 1.07 107961 23751 4 3496.688534 875.1805 ATP-dependent RNA helicase A OS=Homo sapiens OX=9606 GN=DHX9 PE=1 SV=4 4.21 3717.1 - 2.22E+06 - - - -1.2446 - 6.837 0.666 - 962.8 1 2 0 -0.0044 31 0 0 0 1.00E+08 9.39E+07 - - - 5.6059 1 221125_WJC_METTL3_EV_vs_WT_F07.23760.23760.4 3.40E-11 24/126 K.SNAHYNLQNAFNLAEQHLGLTK.L "sp|Q01082|SPTB2_HUMAN,tr|A0A087WUZ3|A0A087WUZ3_HUMAN,tr|F8W6C1|F8W6C1_HUMAN" 3 2482.2353 1.39 107966 23760 4 2482.235647 621.5661 "Spectrin beta chain, non-erythrocytic 1 OS=Homo sapiens OX=9606 GN=SPTBN1 PE=1 SV=2" 6.66 3718.2 - 923442 - - - 0.1317 - 3.784 0.636 - 533.4 1 2 0 0.0003 22 0 0 0 9.70E+07 6.97E+07 - - - 5.1971 0.9763 221125_WJC_METTL3_EV_vs_WT_F07.23761.23761.3 1.14E-07 21/76 K.HAASDVDLEIESLLNQQSTK[136.11].E "sp|Q86U44|MTA70_HUMAN,tr|F5H6D8|F5H6D8_HUMAN,tr|H0YFV6|H0YFV6_HUMAN,tr|B4DTN4|B4DTN4_HUMAN" 4 2205.1005 0.03 107967 23761 3 2206.088155 736.0408 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 4.31 3718.3 - 5.57E+06 - - - 447.9156 - 3.954 0.56 - 546.1 1 2 0 0.9877 20 0 0 0 3.52E+08 1.26E+10 - - - 7.845 1 221125_WJC_METTL3_EV_vs_WT_F07.23762.23762.4 1.78E-12 22/126 K.SNAHYNLQNAFNLAEQHLGLTK[136.11].L "sp|Q01082|SPTB2_HUMAN,tr|A0A087WUZ3|A0A087WUZ3_HUMAN,tr|F8W6C1|F8W6C1_HUMAN" 3 2490.2495 1.39 107968 23762 4 2490.248203 623.5697 "Spectrin beta chain, non-erythrocytic 1 OS=Homo sapiens OX=9606 GN=SPTBN1 PE=1 SV=2" 6.66 3718.4 - 974055 - - - -0.5289 - 3.899 0.658 - 356.3 1 2 0 -0.0013 22 0 0 0 9.69E+07 6.97E+07 - - - 5.3981 1 221125_WJC_METTL3_EV_vs_WT_F07.23763.23763.4 1.31E-07 17/90 R.HYLDFINHYANLFHEK.R "sp|Q14204|DYHC1_HUMAN,tr|A0A7P0T8N2|A0A7P0T8N2_HUMAN,tr|A0A7P0T9C4|A0A7P0T9C4_HUMAN,tr|A0A7P0TBJ7|A0A7P0TBJ7_HUMAN,tr|A0A7P0T9K2|A0A7P0T9K2_HUMAN,tr|A0A2R8Y706|A0A2R8Y706_HUMAN,tr|A0A7P0T916|A0A7P0T916_HUMAN,tr|A0A7P0TB75|A0A7P0TB75_HUMAN,tr|A0A7P0T8W5|A0A7P0T8W5_HUMAN,tr|A0A7P0TAF3|A0A7P0TAF3_HUMAN,tr|A0A7P0T9F1|A0A7P0T9F1_HUMAN,tr|A0A7P0TAW9|A0A7P0TAW9_HUMAN,tr|A0A7P0TA13|A0A7P0TA13_HUMAN,tr|A0A7P0T7V5|A0A7P0T7V5_HUMAN,tr|A0A7P0T9R4|A0A7P0T9R4_HUMAN,tr|A0A2R8Y5T0|A0A2R8Y5T0_HUMAN,tr|A0A2R8YFZ7|A0A2R8YFZ7_HUMAN,tr|A0A7P0T825|A0A7P0T825_HUMAN,tr|A0A2R8Y6H2|A0A2R8Y6H2_HUMAN,tr|A0A7P0TAM4|A0A7P0TAM4_HUMAN" 20 2059.9904 0.93 107969 23763 4 2059.99066 516.0049 Cytoplasmic dynein 1 heavy chain 1 OS=Homo sapiens OX=9606 GN=DYNC1H1 PE=1 SV=5 6.26 3718.6 - 418219 - - - 0.1044 - 3.381 0.509 - 263 1 2 0 0.0002 16 0 0 0 1.53E+07 1.65E+07 - - - 4.0854 1 221125_WJC_METTL3_EV_vs_WT_F07.23776.23776.4 1.00E-09 14/90 R.HYLDFINHYANLFHEK[136.11].R "sp|Q14204|DYHC1_HUMAN,tr|A0A7P0T8N2|A0A7P0T8N2_HUMAN,tr|A0A7P0T9C4|A0A7P0T9C4_HUMAN,tr|A0A7P0TBJ7|A0A7P0TBJ7_HUMAN,tr|A0A7P0T9K2|A0A7P0T9K2_HUMAN,tr|A0A2R8Y706|A0A2R8Y706_HUMAN,tr|A0A7P0T916|A0A7P0T916_HUMAN,tr|A0A7P0TB75|A0A7P0TB75_HUMAN,tr|A0A7P0T8W5|A0A7P0T8W5_HUMAN,tr|A0A7P0TAF3|A0A7P0TAF3_HUMAN,tr|A0A7P0T9F1|A0A7P0T9F1_HUMAN,tr|A0A7P0TAW9|A0A7P0TAW9_HUMAN,tr|A0A7P0TA13|A0A7P0TA13_HUMAN,tr|A0A7P0T7V5|A0A7P0T7V5_HUMAN,tr|A0A7P0T9R4|A0A7P0T9R4_HUMAN,tr|A0A2R8Y5T0|A0A2R8Y5T0_HUMAN,tr|A0A2R8YFZ7|A0A2R8YFZ7_HUMAN,tr|A0A7P0T825|A0A7P0T825_HUMAN,tr|A0A2R8Y6H2|A0A2R8Y6H2_HUMAN,tr|A0A7P0TAM4|A0A7P0TAM4_HUMAN" 20 2068.0046 0.93 107974 23776 4 2068.004697 518.0084 Cytoplasmic dynein 1 heavy chain 1 OS=Homo sapiens OX=9606 GN=DYNC1H1 PE=1 SV=5 6.26 3720.4 - 533750 - - - 0.0251 - 3.178 0.615 - 131.7 1 2 0 0.0001 16 0 0 0 1.54E+07 1.65E+07 - - - 4.9862 1 221125_WJC_METTL3_EV_vs_WT_F07.23787.23787.4 5.24E-10 17/114 K.HAASDVDLEIESLLNQQSTK[136.11].E "sp|Q86U44|MTA70_HUMAN,tr|F5H6D8|F5H6D8_HUMAN,tr|H0YFV6|H0YFV6_HUMAN,tr|B4DTN4|B4DTN4_HUMAN" 4 2205.1005 0.01 107978 23787 4 2205.099001 552.2824 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 4.31 3721.8 - 564984 - - - -0.6598 - 3.576 0.645 - 232.8 1 2 0 -0.0015 20 0 0 0 7.96E+05 7.38E+07 - - - 5.2657 1 221125_WJC_METTL3_EV_vs_WT_F07.23798.23798.2 6.58E-10 23/38 K.HAASDVDLEIESLLNQQSTK[136.11].E "sp|Q86U44|MTA70_HUMAN,tr|F5H6D8|F5H6D8_HUMAN,tr|H0YFV6|H0YFV6_HUMAN,tr|B4DTN4|B4DTN4_HUMAN" 4 2205.1005 0 107982 23798 2 2206.099304 1103.5575 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 4.31 3723.2 - 3.33E+06 - - - 452.9717 - 4.21 0.664 - 1110.8 1 2 0 0.9988 20 0 0 0 1.73E+06 4.17E+08 - - - 7.1657 0.9999 221125_WJC_METTL3_EV_vs_WT_F07.23805.23805.3 3.60E-07 18/64 K.HVINFDLPSDIEEYVHR.L "sp|O00571|DDX3X_HUMAN,sp|O15523|DDX3Y_HUMAN,tr|A0A2R8YFR4|A0A2R8YFR4_HUMAN,tr|A0A2R8YCW1|A0A2R8YCW1_HUMAN,tr|A0A2R8YDT5|A0A2R8YDT5_HUMAN,tr|A0A2R8Y645|A0A2R8Y645_HUMAN,tr|A0A2R8YF78|A0A2R8YF78_HUMAN,tr|A0A0D9SFB3|A0A0D9SFB3_HUMAN,tr|A0A2R8YFS5|A0A2R8YFS5_HUMAN,tr|A0A0D9SF53|A0A0D9SF53_HUMAN,tr|A0A087WVZ1|A0A087WVZ1_HUMAN,tr|A0A0J9YVQ7|A0A0J9YVQ7_HUMAN,tr|A0A2R8Y5G6|A0A2R8Y5G6_HUMAN,tr|A0A2R8Y7T2|A0A2R8Y7T2_HUMAN,tr|A0A0D9SG12|A0A0D9SG12_HUMAN,tr|F6S8Q4|F6S8Q4_HUMAN,tr|A0A2U3TZJ9|A0A2U3TZJ9_HUMAN,tr|A0A2R8Y4A4|A0A2R8Y4A4_HUMAN" 18 2082.0171 1.37 107986 23805 3 2082.010977 695.013 ATP-dependent RNA helicase DDX3X OS=Homo sapiens OX=9606 GN=DDX3X PE=1 SV=3 4.72 3724.2 - 567290 - - - -2.9188 - 2.967 0.551 - 362.9 1 2 0 -0.0061 17 0 0 0 1.99E+07 1.45E+07 - - - 7.4289 1 221125_WJC_METTL3_EV_vs_WT_F07.23807.23807.3 3.73E-10 15/64 K.HVINFDLPSDIEEYVHR[166.11].L "sp|O00571|DDX3X_HUMAN,sp|O15523|DDX3Y_HUMAN,tr|A0A2R8YFR4|A0A2R8YFR4_HUMAN,tr|A0A2R8YCW1|A0A2R8YCW1_HUMAN,tr|A0A2R8YDT5|A0A2R8YDT5_HUMAN,tr|A0A2R8Y645|A0A2R8Y645_HUMAN,tr|A0A2R8YF78|A0A2R8YF78_HUMAN,tr|A0A0D9SFB3|A0A0D9SFB3_HUMAN,tr|A0A2R8YFS5|A0A2R8YFS5_HUMAN,tr|A0A0D9SF53|A0A0D9SF53_HUMAN,tr|A0A087WVZ1|A0A087WVZ1_HUMAN,tr|A0A0J9YVQ7|A0A0J9YVQ7_HUMAN,tr|A0A2R8Y5G6|A0A2R8Y5G6_HUMAN,tr|A0A2R8Y7T2|A0A2R8Y7T2_HUMAN,tr|A0A0D9SG12|A0A0D9SG12_HUMAN,tr|F6S8Q4|F6S8Q4_HUMAN,tr|A0A2U3TZJ9|A0A2U3TZJ9_HUMAN,tr|A0A2R8Y4A4|A0A2R8Y4A4_HUMAN" 18 2092.0253 1.37 107988 23807 3 2092.02552 698.3491 ATP-dependent RNA helicase DDX3X OS=Homo sapiens OX=9606 GN=DDX3X PE=1 SV=3 4.72 3724.4 - 522395 - - - 0.0937 - 3.67 0.595 - 396.3 1 2 0 0.0002 17 0 0 0 1.99E+07 1.45E+07 - - - 8.4583 1 221125_WJC_METTL3_EV_vs_WT_F07.23812.23812.4 2.13E-07 17/96 K.HVINFDLPSDIEEYVHR[166.11].L "sp|O00571|DDX3X_HUMAN,sp|O15523|DDX3Y_HUMAN,tr|A0A2R8YFR4|A0A2R8YFR4_HUMAN,tr|A0A2R8YCW1|A0A2R8YCW1_HUMAN,tr|A0A2R8YDT5|A0A2R8YDT5_HUMAN,tr|A0A2R8Y645|A0A2R8Y645_HUMAN,tr|A0A2R8YF78|A0A2R8YF78_HUMAN,tr|A0A0D9SFB3|A0A0D9SFB3_HUMAN,tr|A0A2R8YFS5|A0A2R8YFS5_HUMAN,tr|A0A0D9SF53|A0A0D9SF53_HUMAN,tr|A0A087WVZ1|A0A087WVZ1_HUMAN,tr|A0A0J9YVQ7|A0A0J9YVQ7_HUMAN,tr|A0A2R8Y5G6|A0A2R8Y5G6_HUMAN,tr|A0A2R8Y7T2|A0A2R8Y7T2_HUMAN,tr|A0A0D9SG12|A0A0D9SG12_HUMAN,tr|F6S8Q4|F6S8Q4_HUMAN,tr|A0A2U3TZJ9|A0A2U3TZJ9_HUMAN,tr|A0A2R8Y4A4|A0A2R8Y4A4_HUMAN" 18 2092.0253 1.26 107989 23812 4 2092.02294 524.0136 ATP-dependent RNA helicase DDX3X OS=Homo sapiens OX=9606 GN=DDX3X PE=1 SV=3 4.72 3725.2 - 345482 - - - -1.1396 - 3.346 0.563 - 362.9 1 2 0 -0.0024 17 0 0 0 1.63E+07 1.30E+07 - - - 4.545 1 221125_WJC_METTL3_EV_vs_WT_F07.23822.23822.4 2.18E-12 26/150 K.SKELTTEIDNNIEQISSYKSEITELR.R "sp|P13645|K1C10_HUMAN,tr|A0A1B0GVI3|A0A1B0GVI3_HUMAN" 2 3039.5248 317.08 107993 23822 4 3039.512814 760.8885 "Keratin, type I cytoskeletal 10 OS=Homo sapiens OX=9606 GN=KRT10 PE=1 SV=6" 4.42 3726.4 - 2.49E+06 - - - -3.945 - 5.63 0.646 - 476.9 1 2 2 -0.012 26 0 0 0 1.11E+08 3.50E+05 - - - 5.3906 0.8191 221125_WJC_METTL3_EV_vs_WT_F07.23835.23835.4 4.38E-07 26/174 R.HIADLAGNSEVILPVPAFNVINGGSHAGNK[136.11].L "sp|P06733|ENOA_HUMAN,tr|A0A2R8Y6G6|A0A2R8Y6G6_HUMAN,tr|K7EM90|K7EM90_HUMAN,tr|A0A2R8YEM5|A0A2R8YEM5_HUMAN" 4 3018.5767 0.81 107998 23835 4 3019.555232 755.6514 Alpha-enolase OS=Homo sapiens OX=9606 GN=ENO1 PE=1 SV=2 5.99 3728.1 - 4.56E+06 - - - 324.1806 - 3.753 0.464 - 340.7 1 2 0 0.9786 30 0 0 0 7.68E+06 9.45E+06 - - - 3.3983 0.9999 221125_WJC_METTL3_EV_vs_WT_F07.23841.23841.4 3.62E-11 28/174 R.TNLDESDVQPVKEQLAQAMFDHIPVGVGSK.G sp|Q9Y3I0|RTCB_HUMAN 1 3251.6132 1.88 108000 23841 4 3251.611233 813.9106 RNA-splicing ligase RtcB homolog OS=Homo sapiens OX=9606 GN=RTCB PE=1 SV=1 4.43 3728.9 - 1.99E+06 - - - -0.6182 - 4.531 0.593 - 302.5 1 2 1 -0.002 30 0 0 0 7.02E+07 3.74E+07 - - - 4.8493 0.9999 221125_WJC_METTL3_EV_vs_WT_F07.23845.23845.4 5.17E-08 25/150 R.SFGTEDRPTDRPIPPRDEVFEYIIFR.G "sp|Q8ND56|LS14A_HUMAN,tr|I3L4Q1|I3L4Q1_HUMAN,tr|A0A140TA76|A0A140TA76_HUMAN,tr|K7EMZ9|K7EMZ9_HUMAN" 4 3151.5727 1 108002 23845 4 3151.570158 788.9005 Protein LSM14 homolog A OS=Homo sapiens OX=9606 GN=LSM14A PE=1 SV=3 4.59 3729.3 - 4.52E+06 - - - -0.8063 - 3.336 0.552 - 107.2 1 2 1 -0.0025 26 0 0 0 1.56E+09 1.56E+09 - - - 4.4099 0.9986 221125_WJC_METTL3_EV_vs_WT_F07.23850.23850.3 2.15E-05 22/76 K.HAASDVDLEIESLLNQQSTK.E "sp|Q86U44|MTA70_HUMAN,tr|F5H6D8|F5H6D8_HUMAN,tr|H0YFV6|H0YFV6_HUMAN,tr|B4DTN4|B4DTN4_HUMAN" 4 2197.0863 0.03 108004 23850 3 2198.083726 733.3694 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 4.31 3729.9 - 6.29E+06 - - - 453.9967 - 4.307 0.498 - 541.8 1 2 0 0.9975 20 0 0 0 3.50E+08 1.26E+10 - - - 7.3585 1 221125_WJC_METTL3_EV_vs_WT_F07.23856.23856.4 1.88E-11 26/174 R.TNLDESDVQPVK[136.11]EQLAQAMFDHIPVGVGSK[136.11].G sp|Q9Y3I0|RTCB_HUMAN 1 3267.6416 1.86 108007 23856 4 3267.638282 817.9177 RNA-splicing ligase RtcB homolog OS=Homo sapiens OX=9606 GN=RTCB PE=1 SV=1 4.43 3730.7 - 1.94E+06 - - - -1.0286 - 3.964 0.621 - 174.2 1 2 1 -0.0034 30 0 0 0 6.98E+07 3.74E+07 - - - 5.0517 0.9999 221125_WJC_METTL3_EV_vs_WT_F07.23863.23863.4 5.03E-09 22/162 R.GPLPLSSQHRGDADQASNILASFGLSAR.D "sp|P43243|MATR3_HUMAN,tr|A8MXP9|A8MXP9_HUMAN,tr|D6R991|D6R991_HUMAN,tr|A0A0R4J2E8|A0A0R4J2E8_HUMAN,tr|D6REM6|D6REM6_HUMAN" 5 2864.4529 1.24 108010 23863 4 2864.453922 717.1205 Matrin-3 OS=Homo sapiens OX=9606 GN=MATR3 PE=1 SV=2 6.75 3731.7 - 1.52E+06 - - - 0.3505 - 3.724 0.598 - 251.9 1 2 1 0.001 28 0 0 0 8.12E+07 6.57E+07 - - - 4.8389 0.9999 221125_WJC_METTL3_EV_vs_WT_F07.23866.23866.4 5.62E-06 19/162 R.GPLPLSSQHR[166.11]GDADQASNILASFGLSAR[166.11].D "sp|P43243|MATR3_HUMAN,tr|A8MXP9|A8MXP9_HUMAN,tr|D6R991|D6R991_HUMAN,tr|A0A0R4J2E8|A0A0R4J2E8_HUMAN,tr|D6REM6|D6REM6_HUMAN" 5 2884.4695 1.24 108012 23866 4 2884.472256 722.1246 Matrin-3 OS=Homo sapiens OX=9606 GN=MATR3 PE=1 SV=2 6.75 3732 - 1.46E+06 - - - 0.97 - 3.144 0.511 - 191 1 2 1 0.0028 28 0 0 0 8.11E+07 6.56E+07 - - - 4.0286 1 221125_WJC_METTL3_EV_vs_WT_F07.23868.23868.4 1.33E-13 21/126 R.ERDSASFNPELLTHILDGSPEK.T "sp|Q15067|ACOX1_HUMAN,tr|K7ELT1|K7ELT1_HUMAN,tr|I3L2U4|I3L2U4_HUMAN,tr|I3L0T4|I3L0T4_HUMAN" 4 2454.2027 1.46 108014 23868 4 2454.20027 614.5579 Peroxisomal acyl-coenzyme A oxidase 1 OS=Homo sapiens OX=9606 GN=ACOX1 PE=1 SV=3 4.5 3732.2 - 807380 - - - -0.9832 - 3.551 0.649 - 375 1 2 1 -0.0024 22 0 0 0 1.80E+07 1.23E+07 - - - 5.2889 0.9998 221125_WJC_METTL3_EV_vs_WT_F07.23869.23869.4 0.00162 9/108 R.GLLQDDAHPTLVTYADHSK[136.11].L "sp|Q86U44|MTA70_HUMAN,tr|F5H6D8|F5H6D8_HUMAN,tr|H0YFV6|H0YFV6_HUMAN,tr|B4DTN4|B4DTN4_HUMAN" 4 2088.0367 0.04 108015 23869 4 2088.031262 523.0165 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 5.13 3732.4 - 269490 - - - -2.6202 - 1.816 0.434 - 74.7 1 2 0 -0.0055 19 0 0 0 5.14E+05 1.41E+07 - - - 3.2039 1 221125_WJC_METTL3_EV_vs_WT_F07.23875.23875.4 9.45E-09 20/126 R.ER[166.11]DSASFNPELLTHILDGSPEK[136.11].T "sp|Q15067|ACOX1_HUMAN,tr|K7ELT1|K7ELT1_HUMAN,tr|I3L2U4|I3L2U4_HUMAN,tr|I3L0T4|I3L0T4_HUMAN" 4 2472.2252 1.47 108018 23875 4 2472.222687 619.0636 Peroxisomal acyl-coenzyme A oxidase 1 OS=Homo sapiens OX=9606 GN=ACOX1 PE=1 SV=3 4.5 3733.2 - 762542 - - - -0.9975 - 3.608 0.645 - 331.6 1 2 1 -0.0025 22 0 0 0 1.80E+07 1.22E+07 - - - 5.2592 0.9233 221125_WJC_METTL3_EV_vs_WT_F07.23883.23883.4 2.15E-07 25/174 R.HIADLAGNSEVILPVPAFNVINGGSHAGNK.L "sp|P06733|ENOA_HUMAN,tr|A0A2R8Y6G6|A0A2R8Y6G6_HUMAN,tr|K7EM90|K7EM90_HUMAN,tr|A0A2R8YEM5|A0A2R8YEM5_HUMAN" 4 3010.5625 0.8 108022 23883 4 3011.544854 753.6479 Alpha-enolase OS=Homo sapiens OX=9606 GN=ENO1 PE=1 SV=2 5.99 3734.2 - 1.25E+06 - - - 326.3131 - 3.576 0.492 - 283.8 1 2 0 0.9824 30 0 0 0 7.43E+06 9.27E+06 - - - 3.6262 0.9997 221125_WJC_METTL3_EV_vs_WT_F07.23896.23896.3 0.000458 10/108 R.GPLPLSSQHR[166.11]GDADQASNILASFGLSAR[166.11].D "sp|P43243|MATR3_HUMAN,tr|A8MXP9|A8MXP9_HUMAN,tr|D6R991|D6R991_HUMAN,tr|A0A0R4J2E8|A0A0R4J2E8_HUMAN,tr|D6REM6|D6REM6_HUMAN" 5 2884.4695 0.98 108029 23896 3 2884.468632 962.4971 Matrin-3 OS=Homo sapiens OX=9606 GN=MATR3 PE=1 SV=2 6.75 3735.9 - 264217 - - - -0.2864 - 2.216 0.464 - 48.3 1 2 1 -0.0008 28 0 0 0 3.29E+06 3.37E+06 - - - 5.5435 1 221125_WJC_METTL3_EV_vs_WT_F07.23901.23901.4 1.29E-13 16/126 R.ESEEENLNK[136.11]SEISQVFEIALK[136.11]R[166.11].N "sp|O95793|STAU1_HUMAN,tr|Q5JW30|Q5JW30_HUMAN,tr|Q5JW28|Q5JW28_HUMAN" 3 2617.3445 2.87 108031 23901 4 2617.354556 655.3434 Double-stranded RNA-binding protein Staufen homolog 1 OS=Homo sapiens OX=9606 GN=STAU1 PE=1 SV=2 4.48 3736.7 - 750183 - - - 3.8245 - 3.475 0.676 - 183 1 2 1 0.01 22 0 0 0 3.97E+07 1.38E+07 - - - 5.5147 0.9994 221125_WJC_METTL3_EV_vs_WT_F07.23924.23924.4 7.95E-05 12/120 K.NPNDPDTVDIILQSLDRDHNK.K sp|Q86YZ3|HORN_HUMAN 1 2418.1775 194.84 108043 23924 4 2418.17829 605.5517 Hornerin OS=Homo sapiens OX=9606 GN=HRNR PE=1 SV=2 4.28 3739.7 - 278052 - - - 0.3139 - 2.091 0.401 - 70.9 1 2 1 0.0008 21 0 0 0 1.19E+07 6.11E+04 - - - 2.96 1 221125_WJC_METTL3_EV_vs_WT_F07.23936.23936.3 3.84E-11 Oct-96 R.EQELHNLLEVVSQC[160.03]C[160.03]EASSSDITEK.S "sp|P52732|KIF11_HUMAN,tr|A0A7I2V3A9|A0A7I2V3A9_HUMAN" 2 2904.3117 3.69 108049 23936 3 2904.323504 969.1112 Kinesin-like protein KIF11 OS=Homo sapiens OX=9606 GN=KIF11 PE=1 SV=2 4.14 3741.4 - 196890 - - - 4.0581 - 2.967 0.68 - 96.1 1 2 0 0.0118 25 0 0 0 3.44E+07 9.32E+06 - - - 8.6201 0.9998 221125_WJC_METTL3_EV_vs_WT_F07.23940.23940.2 0.000529 18-Oct K.ILLAELEQLK.G "sp|P08670|VIME_HUMAN,tr|B0YJC4|B0YJC4_HUMAN,tr|A0A1B0GTT5|A0A1B0GTT5_HUMAN" 3 1168.7067 2.37 108051 23940 2 1168.70594 585.3606 Vimentin OS=Homo sapiens OX=9606 GN=VIM PE=1 SV=4 4.53 3741.9 - 282315 - - - -0.6717 - 1.942 0.437 - 234.9 1 2 0 -0.0008 10 0 0 0 9.96E+06 4.21E+06 - - - 4.1211 1 221125_WJC_METTL3_EV_vs_WT_F07.23960.23960.2 8.22E-06 17/34 R.K[136.11]HAASDVDLEIESLLNQQ.S "sp|Q86U44|MTA70_HUMAN,tr|F5H6D8|F5H6D8_HUMAN,tr|H0YFV6|H0YFV6_HUMAN,tr|B4DTN4|B4DTN4_HUMAN" 4 2017.0207 0.001 108060 23960 2 2017.023967 1009.5177 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 4.31 3744.5 - 1.16E+06 - - - 1.5954 - 3.507 0.584 - 950.4 1 1 0 0.0032 18 0 0 0 0.00E+00 2.85E+07 - - - 6.4383 1 221125_WJC_METTL3_EV_vs_WT_F07.23973.23973.4 7.75E-12 26/126 K.NPDDPDMVDVFMDHLDIDHNKK.L sp|P20930|FILA_HUMAN 1 2609.1526 13.84 108067 23973 4 2609.158227 653.2954 Filaggrin OS=Homo sapiens OX=9606 GN=FLG PE=1 SV=3 4.21 3746.2 - 747499 - - - 2.1421 - 4.417 0.694 - 739.4 1 2 0 0.0056 22 0 0 0 3.19E+07 2.31E+06 - - - 5.7511 0.9551 221125_WJC_METTL3_EV_vs_WT_F07.23978.23978.3 5.48E-05 10/116 R.DNLTLWTSDMQGDGEEQNK[136.11]EALQDVEDENQ.- sp|P62258|1433E_HUMAN 1 3458.4783 0.97 108069 23978 3 3459.470577 1153.8334 14-3-3 protein epsilon OS=Homo sapiens OX=9606 GN=YWHAE PE=1 SV=1 3.48 3746.9 - 714432 - - - 286.9022 - 1.747 0.525 - 61.1 1 2 1 0.9922 30 0 0 0 4.28E+07 4.40E+07 - - - 5.4019 0.9999 221125_WJC_METTL3_EV_vs_WT_F07.23992.23992.3 3.86E-05 14/116 R.DNLTLWTSDMQGDGEEQNKEALQDVEDENQ.- sp|P62258|1433E_HUMAN 1 3450.4641 0.97 108073 23992 3 3450.468323 1151.162 14-3-3 protein epsilon OS=Homo sapiens OX=9606 GN=YWHAE PE=1 SV=1 3.48 3748.9 - 1.42E+06 - - - 1.2146 - 2.497 0.548 - 97.3 1 2 1 0.0042 30 0 0 0 4.28E+07 4.40E+07 - - - 6.7538 0.9996 221125_WJC_METTL3_EV_vs_WT_F07.23993.23993.4 0.000524 13/162 R.ESGGHHYVNMTLPVDAVISVAPEETWGK.V "sp|Q9NUQ7|UFSP2_HUMAN,tr|D6RGX2|D6RGX2_HUMAN,tr|H0YA18|H0YA18_HUMAN" 3 3022.4495 1.34 108074 23993 4 3022.447794 756.6196 Ufm1-specific protease 2 OS=Homo sapiens OX=9606 GN=UFSP2 PE=1 SV=3 4.8 3749 - 251040 - - - -0.5552 - 2.227 0.338 - 74.5 1 2 0 -0.0017 28 0 0 0 8.71E+06 6.51E+06 - - - 2.4161 0.9738 221125_WJC_METTL3_EV_vs_WT_F07.23998.23998.2 0.0214 16-Nov L.NSLIAHAHR.R "sp|Q16891|MIC60_HUMAN,tr|B9A067|B9A067_HUMAN,tr|C9J406|C9J406_HUMAN,tr|H7C463|H7C463_HUMAN" 4 1017.5468 1.19 108076 23998 2 1017.54796 509.7807 MICOS complex subunit MIC60 OS=Homo sapiens OX=9606 GN=IMMT PE=1 SV=1 9.76 3749.7 - 165883 - - - 1.1292 - 2.317 0.276 - 532.3 1 1 0 0.0011 9 0 0 0 4.39E+06 3.68E+06 - - - 3.5101 1 221125_WJC_METTL3_EV_vs_WT_F07.24012.24012.4 1.54E-18 34/144 K.GMSVSDLADK[136.11]LSTDDLNSLIAHAHR[166.11].R "sp|Q16891|MIC60_HUMAN,tr|B9A067|B9A067_HUMAN,tr|C9J406|C9J406_HUMAN,tr|H7C463|H7C463_HUMAN" 4 2683.3354 1.37 108084 24012 4 2683.335748 671.8411 MICOS complex subunit MIC60 OS=Homo sapiens OX=9606 GN=IMMT PE=1 SV=1 5.2 3751.5 - 3.70E+06 - - - 0.1118 - 5.641 0.695 - 878 1 2 1 0.0003 25 0 0 0 1.94E+08 1.42E+08 - - - 5.8256 1 221125_WJC_METTL3_EV_vs_WT_F07.24019.24019.3 1.37E-05 23/76 K.HAASDVDLEIESLLNQQSTK[136.11].E "sp|Q86U44|MTA70_HUMAN,tr|F5H6D8|F5H6D8_HUMAN,tr|H0YFV6|H0YFV6_HUMAN,tr|B4DTN4|B4DTN4_HUMAN" 4 2205.1005 0.29 108088 24019 3 2206.099288 736.0408 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 4.31 3752.4 - 940087 - - - 452.9644 - 4.421 0.634 - 732 1 2 0 0.9988 20 0 0 0 1.16E+07 4.07E+07 - - - 8.9378 1 221125_WJC_METTL3_EV_vs_WT_F07.24022.24022.4 2.35E-09 20/126 K.TSQLLETLNQLSTHTHVVDITR.T "sp|Q14203|DCTN1_HUMAN,tr|A0A804CDA6|A0A804CDA6_HUMAN,tr|E7EX90|E7EX90_HUMAN,tr|A0A7P0Z4C3|A0A7P0Z4C3_HUMAN,tr|E7EWF7|E7EWF7_HUMAN" 5 2505.3187 3.64 108090 24022 4 2505.325088 627.337 Dynactin subunit 1 OS=Homo sapiens OX=9606 GN=DCTN1 PE=1 SV=3 5.92 3752.7 - 627081 - - - 2.5434 - 4.404 0.549 - 415.3 1 2 0 0.0064 22 0 0 0 4.19E+07 1.15E+07 - - - 4.4878 1 221125_WJC_METTL3_EV_vs_WT_F07.24035.24035.4 7.22E-07 22/150 K.SKPWEPFVAEEFAHQFHESVLQSTQK.A "sp|Q14687|GSE1_HUMAN,tr|H7C3B5|H7C3B5_HUMAN,tr|H0Y613|H0Y613_HUMAN" 3 3085.4934 4.12 108096 24035 4 3085.496098 772.3806 Genetic suppressor element 1 OS=Homo sapiens OX=9606 GN=GSE1 PE=1 SV=3 5.38 3754.5 - 398081 - - - 0.879 - 3.774 0.625 - 150.2 1 2 0 0.0027 26 0 0 0 2.16E+07 5.24E+06 - - - 5.0842 0.9986 221125_WJC_METTL3_EV_vs_WT_F07.24045.24045.4 1.69E-05 15/138 R.SEQDVK[136.11]PK[136.11]PVDATDPAALIAEALK[136.11].K "sp|Q15390|MTFR1_HUMAN,tr|H0YBZ4|H0YBZ4_HUMAN,tr|H7C5V5|H7C5V5_HUMAN,tr|H0YF01|H0YF01_HUMAN" 4 2529.3752 3.79 108102 24045 4 2530.374205 633.3511 Mitochondrial fission regulator 1 OS=Homo sapiens OX=9606 GN=MTFR1 PE=1 SV=2 4.44 3755.8 - 292596 - - - 394.9477 - 2.597 0.536 - 149.3 1 2 0 0.999 24 0 0 0 4.46E+07 1.18E+07 - - - 3.9209 0.9998 221125_WJC_METTL3_EV_vs_WT_F07.24052.24052.3 6.70E-05 Nov-76 K.NFGQELAQVQHSIGQLC[160.03]NTK[136.11].D "sp|Q15643|TRIPB_HUMAN,tr|H0YJ97|H0YJ97_HUMAN" 2 2279.1208 0.93 108107 24052 3 2279.12697 760.7142 Thyroid receptor-interacting protein 11 OS=Homo sapiens OX=9606 GN=TRIP11 PE=1 SV=3 6.74 3756.7 - 201752 - - - 2.7006 - 2.285 0.458 - 94.1 1 2 0 0.0062 20 0 0 0 3.99E+06 4.31E+06 - - - 5.6493 0.9981 221125_WJC_METTL3_EV_vs_WT_F07.24066.24066.4 1.91E-05 13/150 K.SGFEPASLKEEVGEEAIVELVENGKK.V "sp|P35579|MYH9_HUMAN,tr|Q5BKV1|Q5BKV1_HUMAN,tr|B1AH99|B1AH99_HUMAN" 3 2787.4178 1.36 108115 24066 4 2787.426992 697.8617 Myosin-9 OS=Homo sapiens OX=9606 GN=MYH9 PE=1 SV=4 4.36 3758.6 - 320046 - - - 3.2901 - 2.579 0.408 - 102.5 1 2 1 0.0092 26 0 0 0 5.42E+06 3.97E+06 - - - 3.0735 1 221125_WJC_METTL3_EV_vs_WT_F07.24071.24071.4 3.28E-07 18/138 R.SEQDVK[136.11]PK[136.11]PVDATDPAALIAEALK[136.11].K "sp|Q15390|MTFR1_HUMAN,tr|H0YBZ4|H0YBZ4_HUMAN,tr|H7C5V5|H7C5V5_HUMAN,tr|H0YF01|H0YF01_HUMAN" 4 2529.3752 3.79 108118 24071 4 2529.377813 633.3511 Mitochondrial fission regulator 1 OS=Homo sapiens OX=9606 GN=MTFR1 PE=1 SV=2 4.44 3759.2 - 619004 - - - 1.0196 - 3.013 0.589 - 183.3 1 2 0 0.0026 24 0 0 0 4.46E+07 1.18E+07 - - - 4.7059 0.9999 221125_WJC_METTL3_EV_vs_WT_F07.24091.24091.3 6.36E-05 19/92 K.TSNTLEK[136.11]DLDLLASVPSPSSSGSR[166.11].K "sp|Q8WU79|SMAP2_HUMAN,tr|A0A087WV97|A0A087WV97_HUMAN" 2 2478.2568 1.97 108129 24091 3 2478.257971 827.0929 Stromal membrane-associated protein 2 OS=Homo sapiens OX=9606 GN=SMAP2 PE=1 SV=1 4.56 3761.8 - 515904 - - - 0.4535 - 3.64 0.51 - 154.9 1 2 1 0.0011 24 0 0 0 9.11E+07 4.62E+07 - - - 7.2264 1 221125_WJC_METTL3_EV_vs_WT_F07.24092.24092.3 1.08E-05 Sep-56 R.DYLHLPPEIVPATLR.R "sp|P46783|RS10_HUMAN,tr|A0A2R8Y6L3|A0A2R8Y6L3_HUMAN,tr|F6U211|F6U211_HUMAN,tr|A0A1W2PQS6|A0A1W2PQS6_HUMAN,tr|A0A2R8YFH6|A0A2R8YFH6_HUMAN,tr|A0A2R8Y7H1|A0A2R8Y7H1_HUMAN,tr|S4R435|S4R435_HUMAN" 7 1732.9512 1.52 108130 24092 3 1732.952696 578.6577 40S ribosomal protein S10 OS=Homo sapiens OX=9606 GN=RPS10 PE=1 SV=1 5.32 3761.9 - 113120 - - - 0.8598 - 1.851 0.533 - 61.3 1 2 0 0.0015 15 0 0 0 1.52E+07 1.00E+07 - - - 6.0887 0.8506 221125_WJC_METTL3_EV_vs_WT_F07.24093.24093.2 0.773 14-Jul K.DIGFIKLD.- "sp|P62273|RS29_HUMAN,tr|A0A087WTT6|A0A087WTT6_HUMAN" 2 919.5015 1 108131 24093 2 919.501793 460.758 40S ribosomal protein S29 OS=Homo sapiens OX=9606 GN=RPS29 PE=1 SV=2 4.54 3762 - 331315 - - - 0.3361 - 0.979 0.187 - 88.7 1 2 1 0.0003 8 0 0 0 7.56E+06 7.55E+06 - - - 0.3581 0.8261 221125_WJC_METTL3_EV_vs_WT_F07.24094.24094.2 0.107 14-May K.DIGFIK[136.11]LD.- "sp|P62273|RS29_HUMAN,tr|A0A087WTT6|A0A087WTT6_HUMAN" 2 927.5157 1 108132 24094 2 927.517244 464.7651 40S ribosomal protein S29 OS=Homo sapiens OX=9606 GN=RPS29 PE=1 SV=2 4.54 3762.1 - 313991 - - - 1.6819 - 1.063 0.22 - 39.2 3 2 1 0.0016 8 0 0 0 7.56E+06 7.55E+06 - - - 0.6366 1 221125_WJC_METTL3_EV_vs_WT_F07.24097.24097.3 1.17E-05 31/92 K.TSNTLEKDLDLLASVPSPSSSGSR.K "sp|Q8WU79|SMAP2_HUMAN,tr|A0A087WV97|A0A087WV97_HUMAN" 2 2460.2344 1.97 108133 24097 3 2460.240663 821.0854 Stromal membrane-associated protein 2 OS=Homo sapiens OX=9606 GN=SMAP2 PE=1 SV=1 4.56 3762.6 - 1.04E+06 - - - 2.555 - 4.463 0.628 - 560.6 1 2 1 0.0063 24 0 0 0 9.11E+07 4.62E+07 - - - 9.014 1 221125_WJC_METTL3_EV_vs_WT_F07.24099.24099.4 5.56E-09 18/228 K.YFSSNPIIPSQSAASSAIAFQPVGTGGVQLC[160.03]GGGSTGSK.G "sp|Q15517|CDSN_HUMAN,tr|G8JLG2|G8JLG2_HUMAN,tr|Q2L6G8|Q2L6G8_HUMAN" 3 3784.8367 999 108135 24099 4 3784.849307 947.2164 Corneodesmosin OS=Homo sapiens OX=9606 GN=CDSN PE=1 SV=3 8.2 3762.8 - 396743 - - - 3.3431 - 4.076 0.651 - 132.1 1 2 0 0.0127 39 0 0 0 2.95E+06 0.00E+00 - - - 5.2964 1 221125_WJC_METTL3_EV_vs_WT_F07.24102.24102.3 6.65E-12 19/152 K.YFSSNPIIPSQSAASSAIAFQPVGTGGVQLC[160.03]GGGSTGSK.G "sp|Q15517|CDSN_HUMAN,tr|G8JLG2|G8JLG2_HUMAN,tr|Q2L6G8|Q2L6G8_HUMAN" 3 3784.8367 999 108138 24102 3 3784.851781 1262.6195 Corneodesmosin OS=Homo sapiens OX=9606 GN=CDSN PE=1 SV=3 8.2 3763.2 - 301509 - - - 3.9967 - 4.152 0.672 - 184.7 1 2 0 0.0151 39 0 0 0 1.78E+06 0.00E+00 - - - 9.3031 0.9601 221125_WJC_METTL3_EV_vs_WT_F07.24103.24103.3 0.192 May-44 R.LFPPQWIC[160.03]C[160.03]DIR[166.11].Y sp|Q86U44|MTA70_HUMAN 1 1613.7722 0.001 108139 24103 3 1613.776922 538.9313 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 5.82 3763.3 - 165839 - - - 2.9199 - 1.121 0.258 - 39.3 1 2 0 0.0047 12 0 0 0 0.00E+00 2.45E+06 - - - 1.7317 1 221125_WJC_METTL3_EV_vs_WT_F07.24109.24109.4 1.56E-09 23/198 R.FLNEHPGGEEVLLEQAGVDASESFEDVGHSSDAR.E "sp|O43169|CYB5B_HUMAN,tr|D6RFH4|D6RFH4_HUMAN,tr|H3BUX2|H3BUX2_HUMAN" 3 3626.6397 1.45 108143 24109 4 3626.646005 907.6672 Cytochrome b5 type B OS=Homo sapiens OX=9606 GN=CYB5B PE=1 SV=3 4.05 3764.1 - 580922 - - - 1.7308 - 5.136 0.689 - 271.1 1 2 0 0.0063 34 0 0 0 2.94E+07 2.02E+07 - - - 5.7093 0.9998 221125_WJC_METTL3_EV_vs_WT_F07.24111.24111.3 9.35E-05 Oct-56 R.DYLHLPPEIVPATLR[166.11].R "sp|P46783|RS10_HUMAN,tr|A0A2R8Y6L3|A0A2R8Y6L3_HUMAN,tr|F6U211|F6U211_HUMAN,tr|A0A1W2PQS6|A0A1W2PQS6_HUMAN,tr|A0A2R8YFH6|A0A2R8YFH6_HUMAN,tr|A0A2R8Y7H1|A0A2R8Y7H1_HUMAN,tr|S4R435|S4R435_HUMAN" 7 1742.9595 1.49 108145 24111 3 1742.964888 581.9938 40S ribosomal protein S10 OS=Homo sapiens OX=9606 GN=RPS10 PE=1 SV=1 5.32 3764.4 - 183284 - - - 3.1051 - 2.047 0.486 - 118.4 1 2 0 0.0054 15 0 0 0 1.45E+07 9.75E+06 - - - 5.8262 1 221125_WJC_METTL3_EV_vs_WT_F07.24116.24116.4 1.25E-17 30/198 R.FLNEHPGGEEVLLEQAGVDASESFEDVGHSSDAR[166.11].E "sp|O43169|CYB5B_HUMAN,tr|D6RFH4|D6RFH4_HUMAN,tr|H3BUX2|H3BUX2_HUMAN" 3 3636.648 1.45 108148 24116 4 3637.655179 910.1693 Cytochrome b5 type B OS=Homo sapiens OX=9606 GN=CYB5B PE=1 SV=3 4.05 3765 - 699156 - - - 276.9531 - 5.846 0.764 - 494.9 1 2 0 1.0072 34 0 0 0 2.94E+07 2.02E+07 - - - 6.1234 1 221125_WJC_METTL3_EV_vs_WT_F07.24118.24118.4 7.30E-11 20/138 K.LNDFRDEQIGQLQELMQEATKPNR.Q sp|Q9NRP4|SDHF3_HUMAN 1 2872.4138 2.2 108150 24118 4 2872.42403 719.1107 "Succinate dehydrogenase assembly factor 3, mitochondrial OS=Homo sapiens OX=9606 GN=SDHAF3 PE=1 SV=1" 4.51 3765.2 - 653443 - - - 3.5771 - 4.995 0.622 - 301.2 1 2 1 0.0103 24 0 0 0 2.57E+07 1.16E+07 - - - 5.1533 0.9995 221125_WJC_METTL3_EV_vs_WT_F07.24125.24125.3 3.95E-07 19/76 K.K[136.11]DELDSLITAITTNGAHPSK[136.11].C "sp|Q13485|SMAD4_HUMAN,tr|K7EIU8|K7EIU8_HUMAN,tr|K7EL18|K7EL18_HUMAN,tr|K7ENG1|K7ENG1_HUMAN,tr|K7EL15|K7EL15_HUMAN,tr|K7EIJ2|K7EIJ2_HUMAN,tr|K7ES96|K7ES96_HUMAN" 7 2126.119 4.36 108154 24125 3 2126.131572 709.7136 Mothers against decapentaplegic homolog 4 OS=Homo sapiens OX=9606 GN=SMAD4 PE=1 SV=1 5.38 3766.3 - 369472 - - - 5.907 - 3.54 0.52 - 498.4 1 2 0 0.0126 20 0 0 0 8.28E+07 1.90E+07 - - - 7.4008 0.9999 221125_WJC_METTL3_EV_vs_WT_F07.24128.24128.4 1.27E-05 18/114 K.KDELDSLITAITTNGAHPSK.C "sp|Q13485|SMAD4_HUMAN,tr|K7EIU8|K7EIU8_HUMAN,tr|K7EL18|K7EL18_HUMAN,tr|K7ENG1|K7ENG1_HUMAN,tr|K7EL15|K7EL15_HUMAN,tr|K7EIJ2|K7EIJ2_HUMAN,tr|K7ES96|K7ES96_HUMAN" 7 2110.0906 1.3 108157 24128 4 2110.096076 528.5299 Mothers against decapentaplegic homolog 4 OS=Homo sapiens OX=9606 GN=SMAD4 PE=1 SV=1 5.38 3766.7 - 315688 - - - 2.589 - 2.907 0.52 - 277.9 1 2 0 0.0055 20 0 0 0 1.98E+07 1.53E+07 - - - 4.1073 0.9998 221125_WJC_METTL3_EV_vs_WT_F07.24129.24129.4 0.000602 9/108 R.GLLQDDAHPTLVTYADHSK[136.11].L "sp|Q86U44|MTA70_HUMAN,tr|F5H6D8|F5H6D8_HUMAN,tr|H0YFV6|H0YFV6_HUMAN,tr|B4DTN4|B4DTN4_HUMAN" 4 2088.0367 0.04 108158 24129 4 2088.039085 523.0165 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 5.13 3766.8 - 240180 - - - 1.1264 - 2.033 0.391 - 63 1 2 0 0.0024 19 0 0 0 2.69E+05 6.28E+06 - - - 2.8686 1 221125_WJC_METTL3_EV_vs_WT_F07.24132.24132.3 2.09E-11 22/112 R.DNSDFDLLTVSETANEPPQDEGNSFNSPR.N sp|O15371|EIF3D_HUMAN 1 3194.3912 1.31 108159 24132 3 3194.389898 1065.8044 Eukaryotic translation initiation factor 3 subunit D OS=Homo sapiens OX=9606 GN=EIF3D PE=1 SV=1 3.62 3767.2 - 446559 - - - -0.4154 - 4.171 0.741 - 336.1 1 2 0 -0.0013 29 0 0 0 7.66E+07 5.86E+07 - - - 10.0867 1 221125_WJC_METTL3_EV_vs_WT_F07.24140.24140.4 3.54E-08 22/114 K.K[136.11]DELDSLITAITTNGAHPSK[136.11].C "sp|Q13485|SMAD4_HUMAN,tr|K7EIU8|K7EIU8_HUMAN,tr|K7EL18|K7EL18_HUMAN,tr|K7ENG1|K7ENG1_HUMAN,tr|K7EL15|K7EL15_HUMAN,tr|K7EIJ2|K7EIJ2_HUMAN,tr|K7ES96|K7ES96_HUMAN" 7 2126.119 1.3 108164 24140 4 2126.121821 532.537 Mothers against decapentaplegic homolog 4 OS=Homo sapiens OX=9606 GN=SMAD4 PE=1 SV=1 5.38 3768.3 - 610801 - - - 1.3207 - 3.512 0.525 - 507.9 1 2 0 0.0028 20 0 0 0 1.98E+07 1.53E+07 - - - 4.2148 0.9892 221125_WJC_METTL3_EV_vs_WT_F07.24141.24141.4 1.97E-05 15/204 K.QSKPVTTPEEIAQVATISANGDKEIGNIISDAMK[136.11]K[136.11].V "sp|P10809|CH60_HUMAN,tr|A0A7I2V599|A0A7I2V599_HUMAN,tr|E7EXB4|E7EXB4_HUMAN,tr|A0A7I2YQ71|A0A7I2YQ71_HUMAN,tr|E7ESH4|E7ESH4_HUMAN,tr|A0A7I2V5M1|A0A7I2V5M1_HUMAN,tr|A0A7I2V5K3|A0A7I2V5K3_HUMAN,tr|A0A7I2V369|A0A7I2V369_HUMAN" 8 3698.9372 - 108165 24141 4 3698.914494 925.7416 "60 kDa heat shock protein, mitochondrial OS=Homo sapiens OX=9606 GN=HSPD1 PE=1 SV=2" 4.94 3768.4 - 599432 - - - -6.1266 - 3.041 0.422 - 64.7 1 2 1 -0.0227 35 0 0 0 - - - - - 3.2225 1 221125_WJC_METTL3_EV_vs_WT_F07.24146.24146.4 4.85E-13 28/138 K.LNDFR[166.11]DEQIGQLQELMQEATK[136.11]PNR[166.11].Q sp|Q9NRP4|SDHF3_HUMAN 1 2900.4445 2.2 108168 24146 4 2900.447139 726.1184 "Succinate dehydrogenase assembly factor 3, mitochondrial OS=Homo sapiens OX=9606 GN=SDHAF3 PE=1 SV=1" 4.51 3769.1 - 1.09E+06 - - - 0.9116 - 5.468 0.624 - 690.1 1 2 1 0.0026 24 0 0 0 2.57E+07 1.16E+07 - - - 5.2019 1 221125_WJC_METTL3_EV_vs_WT_F07.24148.24148.3 1.17E-05 23/76 K.KDELDSLITAITTNGAHPSK.C "sp|Q13485|SMAD4_HUMAN,tr|K7EIU8|K7EIU8_HUMAN,tr|K7EL18|K7EL18_HUMAN,tr|K7ENG1|K7ENG1_HUMAN,tr|K7EL15|K7EL15_HUMAN,tr|K7EIJ2|K7EIJ2_HUMAN,tr|K7ES96|K7ES96_HUMAN" 7 2110.0906 3.27 108170 24148 3 2110.094427 704.3708 Mothers against decapentaplegic homolog 4 OS=Homo sapiens OX=9606 GN=SMAD4 PE=1 SV=1 5.38 3769.3 - 1.09E+06 - - - 1.8075 - 4.112 0.527 - 685.1 1 2 0 0.0038 20 0 0 0 6.22E+07 1.90E+07 - - - 7.8447 0.9998 221125_WJC_METTL3_EV_vs_WT_F07.24166.24166.4 1.65E-14 23/150 K.LQLVKEEYITSALESTEEKLHDAASK.L "sp|P52732|KIF11_HUMAN,tr|A0A7I2YQY4|A0A7I2YQY4_HUMAN,tr|A0A7I2V3A9|A0A7I2V3A9_HUMAN,tr|A0A7I2V3V3|A0A7I2V3V3_HUMAN" 4 2931.5077 29.87 108182 24166 4 2931.516749 733.8842 Kinesin-like protein KIF11 OS=Homo sapiens OX=9606 GN=KIF11 PE=1 SV=2 4.7 3771.7 - 569781 - - - 3.0875 - 5.068 0.587 - 419.1 1 2 2 0.0091 26 0 0 0 1.07E+07 3.60E+05 - - - 4.8447 1 221125_WJC_METTL3_EV_vs_WT_F07.24178.24178.3 2.63E-14 29/104 R.ALYDAELSQMQTHISDTSVVLSMDNNR.N "sp|P48668|K2C6C_HUMAN,sp|P04259|K2C6B_HUMAN,sp|P02538|K2C6A_HUMAN" 3 3037.4121 999 108188 24178 3 3037.414746 1013.478 "Keratin, type II cytoskeletal 6C OS=Homo sapiens OX=9606 GN=KRT6C PE=1 SV=3" 4.22 3773.2 - 1.40E+06 - - - 0.8711 - 5.244 0.728 - 905.4 1 2 0 0.0026 27 0 0 0 1.96E+07 0.00E+00 - - - 10.4681 1 221125_WJC_METTL3_EV_vs_WT_F07.24185.24185.3 7.03E-15 16/120 R.SSGGSGGGPLSHFYSGSPTSYFTSGLQAGLK.Q "tr|K7EQG2|K7EQG2_HUMAN,tr|E9PAU2|E9PAU2_HUMAN,tr|A0A087WZ13|A0A087WZ13_HUMAN" 3 2990.4046 0.95 108192 24185 3 2990.408785 997.8088 Uncharacterized protein (Fragment) OS=Homo sapiens OX=9606 PE=1 SV=1 8.24 3774.2 - 478070 - - - 1.3894 - 3.502 0.616 - 145.1 1 2 0 0.0042 31 0 0 0 1.22E+07 1.29E+07 - - - 8.2901 0.9999 221125_WJC_METTL3_EV_vs_WT_F07.24186.24186.3 4.25E-07 13/68 R.IGPYQPNVPVGIDYVIPK.T "sp|P43243|MATR3_HUMAN,tr|B3KM87|B3KM87_HUMAN,tr|A8MXP9|A8MXP9_HUMAN,tr|A0A0R4J2E8|A0A0R4J2E8_HUMAN" 4 1968.072 1.54 108193 24186 3 1968.074757 657.0313 Matrin-3 OS=Homo sapiens OX=9606 GN=MATR3 PE=1 SV=2 5.83 3774.3 - 266875 - - - 1.3755 - 2.514 0.483 - 157.8 1 2 0 0.0027 18 0 0 0 9.85E+06 6.39E+06 - - - 6.2198 1 221125_WJC_METTL3_EV_vs_WT_F07.24192.24192.3 1.11E-13 19/120 R.SSGGSGGGPLSHFYSGSPTSYFTSGLQAGLK[136.11].Q "tr|K7EQG2|K7EQG2_HUMAN,tr|E9PAU2|E9PAU2_HUMAN,tr|A0A087WZ13|A0A087WZ13_HUMAN" 3 2998.4188 0.92 108195 24192 3 2998.422796 1000.4802 Uncharacterized protein (Fragment) OS=Homo sapiens OX=9606 PE=1 SV=1 8.24 3775.1 - 568986 - - - 1.3227 - 3.748 0.709 - 268.6 1 2 0 0.004 31 0 0 0 1.14E+07 1.24E+07 - - - 9.4832 1 221125_WJC_METTL3_EV_vs_WT_F07.24195.24195.3 2.57E-05 13/68 R.IGPYQPNVPVGIDYVIPK[136.11].T "sp|P43243|MATR3_HUMAN,tr|B3KM87|B3KM87_HUMAN,tr|A8MXP9|A8MXP9_HUMAN,tr|A0A0R4J2E8|A0A0R4J2E8_HUMAN" 4 1976.0863 1.56 108198 24195 3 1976.089587 659.7027 Matrin-3 OS=Homo sapiens OX=9606 GN=MATR3 PE=1 SV=2 5.83 3775.5 - 236104 - - - 1.6887 - 2.596 0.507 - 176.1 1 2 0 0.0033 18 0 0 0 1.01E+07 6.47E+06 - - - 6.5671 0.9999 221125_WJC_METTL3_EV_vs_WT_F07.24200.24200.4 2.95E-05 14/192 R.MPYLSHQQLPAGILPMVPEVAQAVGVSQGHHTK[136.11].D "sp|O95793|STAU1_HUMAN,tr|Q5JW30|Q5JW30_HUMAN" 2 3527.8261 0.53 108201 24200 4 3527.837075 882.9638 Double-stranded RNA-binding protein Staufen homolog 1 OS=Homo sapiens OX=9606 GN=STAU1 PE=1 SV=2 6.81 3776.2 - 238440 - - - 3.111 - 3.397 0.522 - 67.5 1 2 0 0.011 33 0 0 0 8.14E+06 1.55E+07 - - - 4.1334 1 221125_WJC_METTL3_EV_vs_WT_F07.24207.24207.3 2.24E-05 Nov-56 R.NIETIINTFHQYSVK.L sp|P06702|S10A9_HUMAN 1 1805.9312 82.26 108206 24207 3 1805.933898 602.9843 Protein S100-A9 OS=Homo sapiens OX=9606 GN=S100A9 PE=1 SV=1 6.75 3777.1 - 203162 - - - 1.4945 - 2.373 0.508 - 108.6 1 2 0 0.0027 15 0 0 0 1.86E+07 2.26E+05 - - - 6.4578 0.809 221125_WJC_METTL3_EV_vs_WT_F07.24208.24208.2 0.12 18-May E.C[160.03]QDQLQGYER[166.11].K "sp|Q5BJF6|ODFP2_HUMAN,tr|S4R3R9|S4R3R9_HUMAN" 2 1305.5647 0.01 108207 24208 2 1305.565422 653.7896 Outer dense fiber protein 2 OS=Homo sapiens OX=9606 GN=ODF2 PE=1 SV=1 4.37 3777.2 - 179131 - - - 0.5385 - 1.132 0.266 - 90.6 1 1 0 0.0007 10 0 0 0 5.34E+04 5.35E+06 - - - 1.3515 1 221125_WJC_METTL3_EV_vs_WT_F07.24228.24228.3 1.32E-10 18/116 R.DTEGGAAEINC[160.03]NGVIEVINYTQNSNNETLR[166.11].H "sp|Q96SB4|SRPK1_HUMAN,tr|H3BLV9|H3BLV9_HUMAN,tr|D6RBF8|D6RBF8_HUMAN" 3 3304.5141 1.1 108218 24228 3 3305.516392 1102.512 SRSF protein kinase 1 OS=Homo sapiens OX=9606 GN=SRPK1 PE=1 SV=2 3.91 3780 - 321255 - - - 303.2954 - 3.893 0.698 - 359.6 1 2 0 1.0022 30 0 0 0 5.19E+06 4.72E+06 - - - 9.1714 1 221125_WJC_METTL3_EV_vs_WT_F07.24232.24232.3 1.69E-13 21/112 R.DNSDFDLLTVSETANEPPQDEGNSFNSPR[166.11].N sp|O15371|EIF3D_HUMAN 1 3204.3995 1.37 108220 24232 3 3204.407606 1069.1404 Eukaryotic translation initiation factor 3 subunit D OS=Homo sapiens OX=9606 GN=EIF3D PE=1 SV=1 3.62 3780.6 - 356422 - - - 2.5312 - 3.709 0.717 - 264.1 1 2 0 0.0081 29 0 0 0 7.65E+07 5.57E+07 - - - 9.5472 1 221125_WJC_METTL3_EV_vs_WT_F07.24234.24234.3 2.90E-12 26/72 K.NKLNDLEDALQQAKEDLAR.L sp|P04264|K2C1_HUMAN 1 2183.1182 999 108222 24234 3 2183.125709 728.7134 "Keratin, type II cytoskeletal 1 OS=Homo sapiens OX=9606 GN=KRT1 PE=1 SV=6" 4.44 3780.8 - 743982 - - - 3.4281 - 4.718 0.621 - 1018 1 2 2 0.0075 19 0 0 0 7.55E+08 0.00E+00 - - - 9.2729 0.9999 221125_WJC_METTL3_EV_vs_WT_F07.24237.24237.4 9.42E-07 22/108 K.NKLNDLEDALQQAKEDLAR.L sp|P04264|K2C1_HUMAN 1 2183.1182 586.16 108223 24237 4 2183.121504 546.7868 "Keratin, type II cytoskeletal 1 OS=Homo sapiens OX=9606 GN=KRT1 PE=1 SV=6" 4.44 3781.2 - 601375 - - - 1.502 - 3.468 0.583 - 351.1 1 2 2 0.0033 19 0 0 0 3.14E+08 5.36E+05 - - - 4.7202 0.9995 221125_WJC_METTL3_EV_vs_WT_F07.24243.24243.3 1.83E-06 16/168 K.ALANVNIGSLIC[160.03]NVGAGGPAPAAGAAPAGGPAPSTAAAPAEEK[136.11].K sp|P05386|RLA1_HUMAN 1 3815.9356 2.28 108226 24243 3 3816.941147 1272.9858 60S acidic ribosomal protein P1 OS=Homo sapiens OX=9606 GN=RPLP1 PE=1 SV=1 4.53 3782 - 226460 - - - 263.516 - 2.742 0.597 - 88.6 1 2 0 1.0056 43 0 0 0 6.39E+08 2.81E+08 - - - 7.238 1 221125_WJC_METTL3_EV_vs_WT_F07.24245.24245.4 7.58E-09 14/222 K.GILGYTEHQVVSSDFNSDTHSSTFDAGAGIALNDHFVK.L "sp|P04406|G3P_HUMAN,tr|E7EUT5|E7EUT5_HUMAN" 2 4035.8875 1.36 108228 24245 4 4035.877163 1009.9792 Glyceraldehyde-3-phosphate dehydrogenase OS=Homo sapiens OX=9606 GN=GAPDH PE=1 SV=3 4.7 3782.3 - 226098 - - - -2.5623 - 2.765 0.657 - 57.3 1 2 0 -0.0103 38 0 0 0 8.31E+06 6.09E+06 - - - 5.2382 1 221125_WJC_METTL3_EV_vs_WT_F07.24248.24248.4 1.28E-15 50/252 K.ALANVNIGSLIC[160.03]NVGAGGPAPAAGAAPAGGPAPSTAAAPAEEK.K sp|P05386|RLA1_HUMAN 1 3807.9214 1.71 108229 24248 4 3807.927032 952.9876 60S acidic ribosomal protein P1 OS=Homo sapiens OX=9606 GN=RPLP1 PE=1 SV=1 4.53 3782.7 - 2.40E+06 - - - 1.4824 - 6.719 0.643 - 856.8 1 2 0 0.0056 43 0 0 0 2.01E+09 1.18E+09 - - - 5.3633 1 221125_WJC_METTL3_EV_vs_WT_F07.24254.24254.3 1.87E-09 30/168 K.ALANVNIGSLIC[160.03]NVGAGGPAPAAGAAPAGGPAPSTAAAPAEEK.K sp|P05386|RLA1_HUMAN 1 3807.9214 2.28 108233 24254 3 3807.92249 1270.3144 60S acidic ribosomal protein P1 OS=Homo sapiens OX=9606 GN=RPLP1 PE=1 SV=1 4.53 3783.5 - 845466 - - - 0.2897 - 4.716 0.677 - 415.4 1 2 0 0.0011 43 0 0 0 6.39E+08 2.81E+08 - - - 9.6558 1 221125_WJC_METTL3_EV_vs_WT_F07.24259.24259.4 3.14E-10 23/192 R.MPYLSHQQLPAGILPMVPEVAQAVGVSQGHHTK.D "sp|O95793|STAU1_HUMAN,tr|Q5JW30|Q5JW30_HUMAN" 2 3519.8119 1.19 108236 24259 4 3519.812675 880.9603 Double-stranded RNA-binding protein Staufen homolog 1 OS=Homo sapiens OX=9606 GN=STAU1 PE=1 SV=2 6.81 3784.1 - 521663 - - - 0.2202 - 4.841 0.566 - 226.6 1 2 0 0.0008 33 0 0 0 3.09E+07 2.59E+07 - - - 4.6254 1 221125_WJC_METTL3_EV_vs_WT_F07.24264.24264.3 4.84E-12 13/104 K.VLYDAEISQIHQSVTDTNVILSMDNSR.N sp|P35908|K22E_HUMAN 1 3047.487 999 108237 24264 3 3047.485433 1016.8363 "Keratin, type II cytoskeletal 2 epidermal OS=Homo sapiens OX=9606 GN=KRT2 PE=1 SV=2" 4.22 3784.9 - 335958 - - - -0.5076 - 3.467 0.696 - 98.3 1 2 0 -0.0015 27 0 0 0 1.79E+07 0.00E+00 - - - 9.1596 1 221125_WJC_METTL3_EV_vs_WT_F07.24268.24268.3 5.86E-11 16/76 K.HAASDVDLEIESLLNQQSTK[136.11].E "sp|Q86U44|MTA70_HUMAN,tr|F5H6D8|F5H6D8_HUMAN,tr|H0YFV6|H0YFV6_HUMAN,tr|B4DTN4|B4DTN4_HUMAN" 4 2205.1005 0.09 108239 24268 3 2205.10089 736.0408 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 4.31 3785.6 - 282656 - - - 0.1968 - 3.491 0.614 - 271.5 1 2 0 0.0004 20 0 0 0 2.37E+06 2.69E+07 - - - 8.4184 1 221125_WJC_METTL3_EV_vs_WT_F07.24289.24289.4 9.63E-11 30/252 R.APAQNPELTPGPAPAGPTPAPETNAPNHPSPAEYVEVLQELQR.L "sp|P46379|BAG6_HUMAN,tr|A0A7I2V508|A0A7I2V508_HUMAN,tr|A0A0G2JJM1|A0A0G2JJM1_HUMAN,tr|X6REW1|X6REW1_HUMAN,tr|A0A7P0MQS5|A0A7P0MQS5_HUMAN,tr|F6S6P2|F6S6P2_HUMAN,tr|A0A0G2JL47|A0A0G2JL47_HUMAN,tr|A0A024RCR6|A0A024RCR6_HUMAN,tr|A0A0G2JK23|A0A0G2JK23_HUMAN" 9 4452.1986 2.73 108245 24289 4 4452.19346 1114.0569 Large proline-rich protein BAG6 OS=Homo sapiens OX=9606 GN=BAG6 PE=1 SV=2 4.32 3788.7 - 568552 - - - -1.1563 - 4.718 0.574 - 261.6 1 2 0 -0.0051 43 0 0 0 2.34E+08 8.59E+07 - - - 4.6622 0.9885 221125_WJC_METTL3_EV_vs_WT_F07.24296.24296.3 0.00374 13/152 R.AAASSYNTQGAASSLGSYGAQAASYGAQSAASSLAYGAQ.A sp|Q96PK6|RBM14_HUMAN 1 3615.635 - 108247 24296 3 3615.634479 1206.2189 RNA-binding protein 14 OS=Homo sapiens OX=9606 GN=RBM14 PE=1 SV=2 5.57 3789.8 - 586275 - - - -0.1377 - 2.826 0.374 - 87.7 1 1 0 -0.0005 39 0 0 0 - - - - - 5.0996 1 221125_WJC_METTL3_EV_vs_WT_F07.24297.24297.4 4.83E-09 21/156 R.IRSEDEEDLGNARPSAPSTLFDFLESK.M sp|Q9H7E2|TDRD3_HUMAN 1 3022.452 1.76 108248 24297 4 3022.446856 756.6203 Tudor domain-containing protein 3 OS=Homo sapiens OX=9606 GN=TDRD3 PE=1 SV=1 4.2 3789.9 - 565735 - - - -1.6933 - 4.063 0.663 - 274.7 1 2 1 -0.0051 27 0 0 0 3.43E+07 1.95E+07 - - - 5.434 1 221125_WJC_METTL3_EV_vs_WT_F07.24305.24305.2 6.53E-11 13/36 K.NKLNDLEDALQQAKEDLAR.L sp|P04264|K2C1_HUMAN 1 2183.1182 999 108252 24305 2 2183.121302 1092.5664 "Keratin, type II cytoskeletal 1 OS=Homo sapiens OX=9606 GN=KRT1 PE=1 SV=6" 4.44 3790.9 - 172356 - - - 1.4095 - 3.433 0.619 - 284.3 1 2 2 0.0031 19 0 0 0 1.87E+06 0.00E+00 - - - 6.6444 0.9994 221125_WJC_METTL3_EV_vs_WT_F07.24308.24308.3 2.54E-06 Dec-88 K.K[136.11]VSQEILELLNTTTAK[136.11]EQSIVEK[136.11].F "sp|Q86U44|MTA70_HUMAN,tr|H0YFV6|H0YFV6_HUMAN" 2 2624.4699 0.001 108253 24308 3 2624.461761 875.8306 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 4.95 3791.3 - 365179 - - - -3.0871 - 2.411 0.511 - 127.6 1 2 1 -0.0081 23 0 0 0 0.00E+00 1.13E+07 - - - 6.2994 0.9997 221125_WJC_METTL3_EV_vs_WT_F07.24309.24309.3 8.74E-07 9/128 R.AEQDSTTVAAFASSLVSGLNSSASEPAK[136.11]EPAK[136.11]K[136.11].S "sp|Q86U44|MTA70_HUMAN,tr|F5H6D8|F5H6D8_HUMAN,tr|H0YFV6|H0YFV6_HUMAN,tr|B4DTN4|B4DTN4_HUMAN" 4 3301.674 0.001 108254 24309 3 3301.667293 1101.5653 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 4.87 3791.4 - 176525 - - - -2.0299 - 2.363 0.51 - 41 1 2 1 -0.0067 33 0 0 0 0.00E+00 8.38E+06 - - - 6.2025 0.9993 221125_WJC_METTL3_EV_vs_WT_F07.24310.24310.4 0.0655 19/240 R.DATWSPLNHSLLTTVGWDHQVVHHVVPTEPLPAPGPASVTE.- "sp|Q9BQA1|MEP50_HUMAN,tr|H0Y711|H0Y711_HUMAN" 2 4391.1975 - 108255 24310 4 4391.192447 1098.8066 Methylosome protein 50 OS=Homo sapiens OX=9606 GN=WDR77 PE=1 SV=1 5.25 3791.6 - 1.13E+06 - - - -1.1473 - 2.826 0.305 - 75.1 1 2 0 -0.005 41 0 0 0 - - - - - 2.1778 1 221125_WJC_METTL3_EV_vs_WT_F07.24338.24338.4 1.71E-10 43/252 R.APAQNPELTPGPAPAGPTPAPETNAPNHPSPAEYVEVLQELQR[166.11].L "sp|P46379|BAG6_HUMAN,tr|A0A7I2V508|A0A7I2V508_HUMAN,tr|A0A0G2JJM1|A0A0G2JJM1_HUMAN,tr|X6REW1|X6REW1_HUMAN,tr|A0A7P0MQS5|A0A7P0MQS5_HUMAN,tr|F6S6P2|F6S6P2_HUMAN,tr|A0A0G2JL47|A0A0G2JL47_HUMAN,tr|A0A024RCR6|A0A024RCR6_HUMAN,tr|A0A0G2JK23|A0A0G2JK23_HUMAN" 9 4462.2069 2.73 108258 24338 4 4462.205219 1116.559 Large proline-rich protein BAG6 OS=Homo sapiens OX=9606 GN=BAG6 PE=1 SV=2 4.32 3796 - 1.41E+06 - - - -0.3718 - 5.152 0.612 - 553.7 1 2 0 -0.0017 43 0 0 0 2.34E+08 8.59E+07 - - - 5.019 0.9502 221125_WJC_METTL3_EV_vs_WT_F07.24358.24358.4 1.71E-09 26/174 K.KSEAAVPPWVDTNDEETIQQQILALSADKR.N sp|Q96A49|SYAP1_HUMAN 1 3351.6947 1.03 108263 24358 4 3354.699729 838.9309 Synapse-associated protein 1 OS=Homo sapiens OX=9606 GN=SYAP1 PE=1 SV=1 4.3 3798.9 - 1.01E+06 - - - 896.5808 - 3.564 0.619 - 309.7 1 2 0 3.0051 30 0 0 0 3.05E+07 2.96E+07 - - - 4.1703 0.9997 221125_WJC_METTL3_EV_vs_WT_F07.24361.24361.4 0.000461 7/108 R.GLLQDDAHPTLVTYADHSK[136.11].L "sp|Q86U44|MTA70_HUMAN,tr|F5H6D8|F5H6D8_HUMAN,tr|H0YFV6|H0YFV6_HUMAN,tr|B4DTN4|B4DTN4_HUMAN" 4 2088.0367 0 108264 24361 4 2088.036323 523.0165 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 5.13 3799.3 - 213963 - - - -0.1964 - 1.927 0.354 - 28.5 1 2 0 -0.0004 19 0 0 0 3.30E+04 1.84E+07 - - - 2.529 1 221125_WJC_METTL3_EV_vs_WT_F07.24367.24367.4 2.84E-07 19/210 K.QPATVGMAEGNFSGSQPYLQSFPNLAAGSLLVGHHK.Q sp|Q9HCJ3|RAVR2_HUMAN 1 3709.8311 1.4 108265 24367 4 3709.834936 928.4651 Ribonucleoprotein PTB-binding 2 OS=Homo sapiens OX=9606 GN=RAVER2 PE=1 SV=2 6.92 3800.4 - 413202 - - - 1.03 - 3.075 0.621 - 146.2 1 2 0 0.0038 36 0 0 0 6.22E+06 4.46E+06 - - - 4.9613 0.9998 221125_WJC_METTL3_EV_vs_WT_F07.24374.24374.3 6.89E-09 13/56 R.HFYWYLTNEGIQYLR.D "sp|P46783|RS10_HUMAN,tr|A0A2R8Y6L3|A0A2R8Y6L3_HUMAN,tr|F6U211|F6U211_HUMAN,tr|A0A1W2PQS6|A0A1W2PQS6_HUMAN,tr|A0A2R8YFH6|A0A2R8YFH6_HUMAN,tr|A0A2R8Y7H1|A0A2R8Y7H1_HUMAN,tr|S4R435|S4R435_HUMAN" 7 2001.9737 1.28 108268 24374 3 2001.982958 668.3319 40S ribosomal protein S10 OS=Homo sapiens OX=9606 GN=RPS10 PE=1 SV=1 6.75 3801.3 - 382678 - - - 4.608 - 2.976 0.575 - 317.1 1 2 0 0.0092 15 0 0 0 1.36E+07 1.07E+07 - - - 7.7938 0.905 221125_WJC_METTL3_EV_vs_WT_F07.24383.24383.3 0.469 Apr-44 R.LFPPQWIC[160.03]C[160.03]DIR[166.11].Y sp|Q86U44|MTA70_HUMAN 1 1613.7722 0.001 108272 24383 3 1613.771349 538.9313 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 5.82 3802.5 - 87207.1 - - - -0.5335 - 0.987 0.177 - 27.9 1 2 0 -0.0009 12 0 0 0 0.00E+00 4.30E+06 - - - 0.4769 0.9992 221125_WJC_METTL3_EV_vs_WT_F07.24387.24387.4 6.33E-10 21/162 K.HAVSDPSILDSLDLNEDEREVLINNINR.R "sp|P05198|IF2A_HUMAN,tr|H0YJS4|H0YJS4_HUMAN,tr|G3V4T5|G3V4T5_HUMAN" 3 3189.5902 0.75 108275 24387 4 3189.605989 798.4048 Eukaryotic translation initiation factor 2 subunit 1 OS=Homo sapiens OX=9606 GN=EIF2S1 PE=1 SV=3 4.14 3803 - 336433 - - - 4.9505 - 3.885 0.577 - 308.1 1 2 1 0.0158 28 0 0 0 8.69E+06 1.15E+07 - - - 4.6652 1 221125_WJC_METTL3_EV_vs_WT_F07.24393.24393.4 6.14E-13 33/234 R.SSSAASGSYGHLSAGALSPAFTFPHPINPVAYQQILSQQR.G "sp|P10070|GLI2_HUMAN,tr|A0A7I2PJA1|A0A7I2PJA1_HUMAN" 2 4142.061 0.7 108279 24393 4 4142.072826 1036.5225 Zinc finger protein GLI2 OS=Homo sapiens OX=9606 GN=GLI2 PE=1 SV=4 8.36 3803.8 - 505087 - - - 2.857 - 5.52 0.685 - 481.1 1 2 0 0.0118 40 0 0 0 7.10E+06 1.01E+07 - - - 5.6781 0.9988 221125_WJC_METTL3_EV_vs_WT_F07.24410.24410.3 1.31E-08 19/76 W.ITLGNQLDGIHLLDPDVVAR[166.11].F sp|Q86U44|MTA70_HUMAN 1 2168.1829 0.001 108288 24410 3 2168.182169 723.7349 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 4.41 3806 - 645904 - - - -0.3312 - 3.308 0.587 - 325.1 1 1 0 -0.0007 20 0 0 0 0.00E+00 8.51E+07 - - - 7.9866 1 221125_WJC_METTL3_EV_vs_WT_F07.24413.24413.4 6.56E-06 14/114 K.TLSYLLPAIVHINHQPFLER.G "sp|P17844|DDX5_HUMAN,tr|A0A7I2V5F5|A0A7I2V5F5_HUMAN,tr|J3QRN5|J3QRN5_HUMAN,tr|A0A7I2V507|A0A7I2V507_HUMAN,tr|J3KTA4|J3KTA4_HUMAN,tr|A0A0G2JLI4|A0A0G2JLI4_HUMAN,tr|A0A7I2V2S0|A0A7I2V2S0_HUMAN,tr|J3QRQ7|J3QRQ7_HUMAN" 8 2360.3005 1.87 108290 24413 4 2360.305758 591.0824 Probable ATP-dependent RNA helicase DDX5 OS=Homo sapiens OX=9606 GN=DDX5 PE=1 SV=1 6.61 3806.4 - 299111 - - - 2.2332 - 2.361 0.537 - 89.5 1 2 0 0.0053 20 0 0 0 5.30E+06 2.83E+06 - - - 4.1858 1 221125_WJC_METTL3_EV_vs_WT_F07.24414.24414.4 3.65E-10 22/234 R.SSSAASGSYGHLSAGALSPAFTFPHPINPVAYQQILSQQR[166.11].G "sp|P10070|GLI2_HUMAN,tr|A0A7I2PJA1|A0A7I2PJA1_HUMAN" 2 4152.0693 0.7 108291 24414 4 4152.075693 1039.0246 Zinc finger protein GLI2 OS=Homo sapiens OX=9606 GN=GLI2 PE=1 SV=4 8.36 3806.5 - 662174 - - - 1.5489 - 3.95 0.581 - 136.7 1 2 0 0.0064 40 0 0 0 7.10E+06 1.01E+07 - - - 4.6778 1 221125_WJC_METTL3_EV_vs_WT_F07.24419.24419.4 2.25E-17 37/174 K.K[136.11]SEAAVPPWVDTNDEETIQQQILALSADK[136.11]R[166.11].N sp|Q96A49|SYAP1_HUMAN 1 3377.7313 1.66 108294 24419 4 3377.730626 845.4401 Synapse-associated protein 1 OS=Homo sapiens OX=9606 GN=SYAP1 PE=1 SV=1 4.3 3807.2 - 1.82E+07 - - - -0.2096 - 5.071 0.756 - 643.7 1 2 0 -0.0007 30 0 0 0 6.94E+09 4.17E+09 - - - 6.3028 0.9997 221125_WJC_METTL3_EV_vs_WT_F07.24421.24421.3 0.000267 Nov-56 K.VSQEILELLNTTTAK[136.11].E "sp|Q86U44|MTA70_HUMAN,tr|H0YFV6|H0YFV6_HUMAN" 2 1666.9233 0.02 108296 24421 3 1666.919793 556.6484 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 4.53 3807.4 - 211667 - - - -2.0841 - 2.534 0.35 - 222.7 1 2 0 -0.0035 15 0 0 0 7.47E+06 4.27E+08 - - - 4.8674 1 221125_WJC_METTL3_EV_vs_WT_F07.24426.24426.3 9.79E-19 35/116 K.K[136.11]SEAAVPPWVDTNDEETIQQQILALSADK[136.11]R[166.11].N sp|Q96A49|SYAP1_HUMAN 1 3377.7313 2.28 108298 24426 3 3377.729314 1126.9177 Synapse-associated protein 1 OS=Homo sapiens OX=9606 GN=SYAP1 PE=1 SV=1 4.3 3808 - 2.12E+06 - - - -0.598 - 4.37 0.742 - 827.3 1 2 0 -0.002 30 0 0 0 4.26E+08 1.87E+08 - - - 10.2049 1 221125_WJC_METTL3_EV_vs_WT_F07.24435.24435.3 2.75E-10 34/116 K.KSEAAVPPWVDTNDEETIQQQILALSADKR.N sp|Q96A49|SYAP1_HUMAN 1 3351.6947 2.3 108302 24435 3 3351.690239 1118.2388 Synapse-associated protein 1 OS=Homo sapiens OX=9606 GN=SYAP1 PE=1 SV=1 4.3 3809.2 - 8.42E+06 - - - -1.3202 - 4.901 0.71 - 718.3 1 2 0 -0.0044 30 0 0 0 4.26E+08 1.86E+08 - - - 10.1113 1 221125_WJC_METTL3_EV_vs_WT_F07.24469.24469.4 8.04E-08 21/156 K.TFNQVEIKPEMIGHYLGEFSITYKPVK.H "sp|P62841|RS15_HUMAN,tr|K7EM56|K7EM56_HUMAN,tr|A0A0B4J2B4|A0A0B4J2B4_HUMAN,tr|K7ELC2|K7ELC2_HUMAN,tr|S4R417|S4R417_HUMAN" 5 3167.6365 1.17 108310 24469 4 3167.634502 792.9164 40S ribosomal protein S15 OS=Homo sapiens OX=9606 GN=RPS15 PE=1 SV=2 6.43 3814 - 1.93E+06 - - - -0.6446 - 3.624 0.581 - 149.2 1 2 0 -0.002 27 0 0 0 1.00E+08 8.54E+07 - - - 4.6853 1 221125_WJC_METTL3_EV_vs_WT_F07.24479.24479.4 1.29E-12 25/156 K.TFNQVEIK[136.11]PEMIGHYLGEFSITYK[136.11]PVK[136.11].H "sp|P62841|RS15_HUMAN,tr|K7EM56|K7EM56_HUMAN,tr|A0A0B4J2B4|A0A0B4J2B4_HUMAN,tr|K7ELC2|K7ELC2_HUMAN,tr|S4R417|S4R417_HUMAN" 5 3191.6791 1.17 108315 24479 4 3191.678645 798.9271 40S ribosomal protein S15 OS=Homo sapiens OX=9606 GN=RPS15 PE=1 SV=2 6.43 3815.1 - 1.32E+06 - - - -0.1563 - 3.898 0.63 - 249.2 1 2 0 -0.0005 27 0 0 0 9.97E+07 8.51E+07 - - - 5.1351 1 221125_WJC_METTL3_EV_vs_WT_F07.24481.24481.4 6.95E-13 18/252 K.DLTVC[160.03]EPPKPQC[160.03]SLPQDPAIVQSSLGSSTSSFQSMGSYGPFGR.M "sp|Q8ND56|LS14A_HUMAN,tr|A0A140TA76|A0A140TA76_HUMAN,tr|K7EMZ9|K7EMZ9_HUMAN" 3 4599.1356 0.92 108317 24481 4 4599.130196 1150.7912 Protein LSM14 homolog A OS=Homo sapiens OX=9606 GN=LSM14A PE=1 SV=3 4.56 3815.4 - 1.01E+06 - - - -1.1783 - 3.817 0.66 - 120.1 1 2 0 -0.0054 43 0 0 0 4.05E+08 4.41E+08 - - - 5.3504 1 221125_WJC_METTL3_EV_vs_WT_F07.24485.24485.3 8.01E-15 24/104 K.TFNQVEIKPEMIGHYLGEFSITYKPVK.H "sp|P62841|RS15_HUMAN,tr|K7EM56|K7EM56_HUMAN,tr|A0A0B4J2B4|A0A0B4J2B4_HUMAN,tr|K7ELC2|K7ELC2_HUMAN,tr|S4R417|S4R417_HUMAN" 5 3167.6365 1.26 108319 24485 3 3167.631488 1056.8861 40S ribosomal protein S15 OS=Homo sapiens OX=9606 GN=RPS15 PE=1 SV=2 6.43 3816 - 252442 - - - -1.5961 - 4.859 0.667 - 501.6 1 2 0 -0.0051 27 0 0 0 1.70E+07 1.35E+07 - - - 9.6119 1 221125_WJC_METTL3_EV_vs_WT_F07.24486.24486.4 3.86E-07 19/120 K.NPDDPDTVDVIMHMLDRDHDR.R sp|Q5D862|FILA2_HUMAN 1 2505.1013 621.7 108320 24486 4 2505.102033 627.2826 Filaggrin-2 OS=Homo sapiens OX=9606 GN=FLG2 PE=1 SV=1 4.21 3816.1 - 179030 - - - 0.3042 - 3.574 0.662 - 305.9 1 2 1 0.0008 21 0 0 0 3.90E+07 6.28E+04 - - - 5.409 1 221125_WJC_METTL3_EV_vs_WT_F07.24491.24491.3 1.94E-12 31/120 K.INSSPNVNTTASGVEDLNIIQVTIPDDDNER.L "sp|P78347|GTF2I_HUMAN,tr|A0A494C1K3|A0A494C1K3_HUMAN" 2 3339.6066 2.03 108322 24491 3 3339.605193 1114.2095 General transcription factor II-I OS=Homo sapiens OX=9606 GN=GTF2I PE=1 SV=2 3.66 3816.8 - 3.29E+06 - - - -0.4324 - 4.62 0.677 - 434.7 1 2 0 -0.0014 31 0 0 0 3.10E+08 1.53E+08 - - - 9.6084 1 221125_WJC_METTL3_EV_vs_WT_F07.24501.24501.3 5.50E-12 31/120 R.TTPPEAAQNGQSPMAALILVADNAGGSHASK.D sp|Q7Z5L9|I2BP2_HUMAN 1 3003.472 1.59 108326 24501 3 3003.470872 1002.1646 Interferon regulatory factor 2-binding protein 2 OS=Homo sapiens OX=9606 GN=IRF2BP2 PE=1 SV=2 5.29 3818 - 1.48E+06 - - - -0.3749 - 4.774 0.681 - 815.1 1 2 0 -0.0011 31 0 0 0 1.21E+08 7.63E+07 - - - 9.7285 0.9991 221125_WJC_METTL3_EV_vs_WT_F07.24504.24504.4 2.43E-07 15/180 R.TTPPEAAQNGQSPMAALILVADNAGGSHASK[136.11].D sp|Q7Z5L9|I2BP2_HUMAN 1 3011.4862 0.81 108328 24504 4 3012.487328 753.8788 Interferon regulatory factor 2-binding protein 2 OS=Homo sapiens OX=9606 GN=IRF2BP2 PE=1 SV=2 5.29 3818.4 - 442045 - - - 332.4372 - 2.752 0.528 - 66.9 1 2 0 1.0011 31 0 0 0 5.63E+07 6.95E+07 - - - 3.8521 1 221125_WJC_METTL3_EV_vs_WT_F07.24510.24510.2 9.24E-13 14/60 K.INSSPNVNTTASGVEDLNIIQVTIPDDDNER.L "sp|P78347|GTF2I_HUMAN,tr|A0A494C1K3|A0A494C1K3_HUMAN" 2 3339.6066 3.44 108330 24510 2 3339.600456 1670.8106 General transcription factor II-I OS=Homo sapiens OX=9606 GN=GTF2I PE=1 SV=2 3.66 3819.2 - 0 - - - -1.8508 - 3.281 0.753 - 150.3 1 2 0 -0.0062 31 0 0 0 4.10E+06 1.19E+06 - - - 7.5218 1 221125_WJC_METTL3_EV_vs_WT_F07.24511.24511.4 4.47E-10 21/180 K.INSSPNVNTTASGVEDLNIIQVTIPDDDNER.L "sp|P78347|GTF2I_HUMAN,tr|A0A494C1K3|A0A494C1K3_HUMAN" 2 3339.6066 4.42 108331 24511 4 3339.596661 835.9089 General transcription factor II-I OS=Homo sapiens OX=9606 GN=GTF2I PE=1 SV=2 3.66 3819.3 - 1.37E+06 - - - -2.9872 - 3.548 0.609 - 121.2 1 2 0 -0.01 31 0 0 0 4.04E+07 9.13E+06 - - - 4.9089 1 221125_WJC_METTL3_EV_vs_WT_F07.24515.24515.4 7.42E-09 23/180 R.TTPPEAAQNGQSPMAALILVADNAGGSHASK.D sp|Q7Z5L9|I2BP2_HUMAN 1 3003.472 0.91 108333 24515 4 3003.469705 751.8753 Interferon regulatory factor 2-binding protein 2 OS=Homo sapiens OX=9606 GN=IRF2BP2 PE=1 SV=2 5.29 3819.9 - 1.07E+06 - - - -0.7634 - 2.95 0.599 - 49.5 1 2 0 -0.0023 31 0 0 0 5.63E+07 6.20E+07 - - - 4.7678 1 221125_WJC_METTL3_EV_vs_WT_F07.24516.24516.3 2.76E-11 32/72 R.NKLNDLEEALQQAKEDLAR.L sp|P35908|K22E_HUMAN 1 2197.1339 456.55 108334 24516 3 2197.131235 733.3852 "Keratin, type II cytoskeletal 2 epidermal OS=Homo sapiens OX=9606 GN=KRT2 PE=1 SV=2" 4.51 3820 - 2.24E+06 - - - -1.2016 - 5.771 0.666 - 2076.4 1 2 2 -0.0026 19 0 0 0 9.41E+07 2.06E+05 - - - 10.2709 1 221125_WJC_METTL3_EV_vs_WT_F07.24517.24517.4 3.50E-06 26/162 R.VAIEHLDKISDSVLVDIKDTEPLIQTAK.T "sp|P48643|TCPE_HUMAN,tr|E9PCA1|E9PCA1_HUMAN,tr|B7ZAR1|B7ZAR1_HUMAN,tr|E7ENZ3|E7ENZ3_HUMAN" 4 3089.686 0.63 108335 24517 4 3089.688248 773.4288 T-complex protein 1 subunit epsilon OS=Homo sapiens OX=9606 GN=CCT5 PE=1 SV=1 4.52 3820.1 - 810681 - - - 0.7286 - 4.216 0.629 - 65 1 2 2 0.0023 28 0 0 0 5.53E+07 8.72E+07 - - - 5.1469 1 221125_WJC_METTL3_EV_vs_WT_F07.24518.24518.4 1.13E-09 14/108 R.LNEQYEHASIHLWDLLEGK.E "sp|Q14444|CAPR1_HUMAN,tr|G3V153|G3V153_HUMAN" 2 2294.1331 1.09 108336 24518 4 2294.131426 574.5406 Caprin-1 OS=Homo sapiens OX=9606 GN=CAPRIN1 PE=1 SV=2 4.8 3820.3 - 608584 - - - -0.7502 - 3.034 0.64 - 134.2 1 2 0 -0.0017 19 0 0 0 6.55E+06 5.99E+06 - - - 5.1715 0.9996 221125_WJC_METTL3_EV_vs_WT_F07.24522.24522.4 1.18E-05 22/108 R.NKLNDLEEALQQAKEDLAR.L sp|P35908|K22E_HUMAN 1 2197.1339 999 108338 24522 4 2197.134354 550.2907 "Keratin, type II cytoskeletal 2 epidermal OS=Homo sapiens OX=9606 GN=KRT2 PE=1 SV=2" 4.51 3820.8 - 489504 - - - 0.218 - 3.531 0.401 - 338.2 1 2 2 0.0005 19 0 0 0 3.77E+07 0.00E+00 - - - 3.1429 1 221125_WJC_METTL3_EV_vs_WT_F07.24525.24525.4 7.71E-07 16/270 K.GSLGGGFSSGGFSGGSFSRGSSGGGC[160.03]FGGSSGGYGGLGGFGGGSFR.G "sp|P13645|K1C10_HUMAN,tr|A0A1B0GVI3|A0A1B0GVI3_HUMAN" 2 4030.7314 3.35 108340 24525 4 4031.705059 1008.6901 "Keratin, type I cytoskeletal 10 OS=Homo sapiens OX=9606 GN=KRT10 PE=1 SV=6" 9.5 3821.1 - 958296 - - - 241.5703 - 2.81 0.693 - 56.5 1 2 1 0.9737 46 0 0 0 1.31E+06 3.93E+05 - - - 5.2784 1 221125_WJC_METTL3_EV_vs_WT_F07.24528.24528.4 6.11E-11 22/162 R.VAIEHLDK[136.11]ISDSVLVDIK[136.11]DTEPLIQTAK[136.11].T "sp|P48643|TCPE_HUMAN,tr|E9PCA1|E9PCA1_HUMAN,tr|B7ZAR1|B7ZAR1_HUMAN,tr|E7ENZ3|E7ENZ3_HUMAN" 4 3113.7286 0.63 108341 24528 4 3113.724546 779.4394 T-complex protein 1 subunit epsilon OS=Homo sapiens OX=9606 GN=CCT5 PE=1 SV=1 4.52 3821.5 - 867235 - - - -1.301 - 4.349 0.618 - 226.7 1 2 2 -0.0041 28 0 0 0 5.53E+07 8.72E+07 - - - 5.0603 0.999 221125_WJC_METTL3_EV_vs_WT_F07.24543.24543.3 3.11E-11 21/120 R.TTPPEAAQNGQSPMAALILVADNAGGSHASK[136.11].D sp|Q7Z5L9|I2BP2_HUMAN 1 3011.4862 1.59 108348 24543 3 3012.480508 1004.836 Interferon regulatory factor 2-binding protein 2 OS=Homo sapiens OX=9606 GN=IRF2BP2 PE=1 SV=2 5.29 3823.5 - 2.22E+06 - - - 330.1725 - 4.205 0.617 - 315.5 1 2 0 0.9943 31 0 0 0 1.21E+08 7.63E+07 - - - 8.4479 1 221125_WJC_METTL3_EV_vs_WT_F07.24546.24546.3 7.37E-11 17/168 K.DLTVC[160.03]EPPK[136.11]PQC[160.03]SLPQDPAIVQSSLGSSTSSFQSMGSYGPFGR[166.11].M "sp|Q8ND56|LS14A_HUMAN,tr|A0A140TA76|A0A140TA76_HUMAN,tr|K7EMZ9|K7EMZ9_HUMAN" 3 4617.1581 0.94 108349 24546 3 4617.153818 1540.06 Protein LSM14 homolog A OS=Homo sapiens OX=9606 GN=LSM14A PE=1 SV=3 4.56 3823.9 - 352620 - - - -0.9242 - 3.66 0.672 - 163.2 1 2 0 -0.0043 43 0 0 0 1.22E+07 1.31E+07 - - - 9.0159 0.7801 221125_WJC_METTL3_EV_vs_WT_F07.24557.24557.4 0.0073 15/198 K.QSKPVTTPEEIAQVATISANGDK[136.11]EIGNIISDAMK[136.11].K "sp|P10809|CH60_HUMAN,tr|A0A7I2V599|A0A7I2V599_HUMAN,tr|E7EXB4|E7EXB4_HUMAN,tr|A0A7I2YQ71|A0A7I2YQ71_HUMAN,tr|E7ESH4|E7ESH4_HUMAN,tr|A0A7I2V5M1|A0A7I2V5M1_HUMAN,tr|A0A7I2V5K3|A0A7I2V5K3_HUMAN,tr|A0A7I2V369|A0A7I2V369_HUMAN" 8 3570.8422 - 108354 24557 4 3570.810135 893.7178 "60 kDa heat shock protein, mitochondrial OS=Homo sapiens OX=9606 GN=HSPD1 PE=1 SV=2" 4.51 3825.5 - 1.86E+06 - - - -8.9777 - 3.229 0.308 - 74 1 2 1 -0.0321 34 0 0 0 - - - - - 2.2475 1 221125_WJC_METTL3_EV_vs_WT_F07.24562.24562.3 3.00E-14 15/168 K.DLTVC[160.03]EPPKPQC[160.03]SLPQDPAIVQSSLGSSTSSFQSMGSYGPFGR.M "sp|Q8ND56|LS14A_HUMAN,tr|A0A140TA76|A0A140TA76_HUMAN,tr|K7EMZ9|K7EMZ9_HUMAN" 3 4599.1356 0.94 108357 24562 3 4599.130445 1534.0525 Protein LSM14 homolog A OS=Homo sapiens OX=9606 GN=LSM14A PE=1 SV=3 4.56 3826.1 - 563129 - - - -1.1241 - 3.788 0.758 - 129.9 1 2 0 -0.0052 43 0 0 0 1.22E+07 1.31E+07 - - - 10.0536 0.9992 221125_WJC_METTL3_EV_vs_WT_F07.24564.24564.2 0.0606 18-Aug K.FLLFGIQDGK.R "sp|P22105|TENX_HUMAN,tr|A0A140TA52|A0A140TA52_HUMAN,tr|A0A140T956|A0A140T956_HUMAN,tr|A0A140TA33|A0A140TA33_HUMAN,tr|A0A140T8Y3|A0A140T8Y3_HUMAN,tr|A0A3B3ISX9|A0A3B3ISX9_HUMAN,tr|A0A140T9C0|A0A140T9C0_HUMAN,tr|A0A140T902|A0A140T902_HUMAN,tr|A0A140T8Z8|A0A140T8Z8_HUMAN,tr|A0A140TA41|A0A140TA41_HUMAN" 10 1136.623 211.65 108359 24564 2 1136.623587 569.3188 Tenascin-X OS=Homo sapiens OX=9606 GN=TNXB PE=1 SV=5 5.84 3826.4 - 515392 - - - 0.52 - 1.603 0.313 - 180.9 1 2 0 0.0006 10 0 0 0 1.05E+07 4.96E+04 - - - 2.6698 0.7833 221125_WJC_METTL3_EV_vs_WT_F07.24567.24567.3 8.03E-07 20/108 D.STTVAAFASSLVSGLNSSASEPAK[136.11]EPAK[136.11].K "sp|Q86U44|MTA70_HUMAN,tr|F5H6D8|F5H6D8_HUMAN,tr|H0YFV6|H0YFV6_HUMAN,tr|B4DTN4|B4DTN4_HUMAN" 4 2722.3996 0.01 108360 24567 3 2723.398241 908.4738 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 5.86 3826.8 - 774235 - - - 366.822 - 3.917 0.569 - 263.2 1 1 1 0.9986 28 0 0 0 1.14E+05 2.01E+07 - - - 7.7483 0.9999 221125_WJC_METTL3_EV_vs_WT_F07.24574.24574.3 3.57E-05 19/88 K.QKQETLQEEITSLQSSVQQYEEK.N "sp|Q8IWJ2|GCC2_HUMAN,tr|H7BYJ9|H7BYJ9_HUMAN" 2 2752.3403 2.4 108363 24574 3 2752.339282 918.454 GRIP and coiled-coil domain-containing protein 2 OS=Homo sapiens OX=9606 GN=GCC2 PE=1 SV=4 4.33 3827.7 - 699034 - - - -0.3695 - 3.784 0.532 - 365.6 1 2 1 -0.001 23 0 0 0 2.51E+07 1.05E+07 - - - 7.5929 0.9473 221125_WJC_METTL3_EV_vs_WT_F07.24587.24587.3 0.0894 Jun-52 K.GAVHDVKDVLDSVL.- sp|P81605|DCD_HUMAN 1 1465.7777 25.97 108370 24587 3 1465.780606 489.5998 Dermcidin OS=Homo sapiens OX=9606 GN=DCD PE=1 SV=2 4.41 3829.4 - 248083 - - - 2.0105 - 1.1 0.297 - 38.9 1 2 1 0.0029 14 0 0 0 5.34E+06 2.06E+05 - - - 2.1037 1 221125_WJC_METTL3_EV_vs_WT_F07.24590.24590.4 6.94E-18 32/174 K.KSEAAVPPWVDTNDEETIQQQILALSADKR.N sp|Q96A49|SYAP1_HUMAN 1 3351.6947 1.39 108371 24590 4 3351.695054 838.9309 Synapse-associated protein 1 OS=Homo sapiens OX=9606 GN=SYAP1 PE=1 SV=1 4.3 3829.8 - 6.66E+06 - - - 0.1164 - 5.296 0.7 - 552.2 1 2 0 0.0004 30 0 0 0 5.87E+08 4.22E+08 - - - 5.8288 0.99 221125_WJC_METTL3_EV_vs_WT_F07.24601.24601.3 2.01E-05 Oct-76 K.HAASDVDLEIESLLNQQSTK[136.11].E "sp|Q86U44|MTA70_HUMAN,tr|F5H6D8|F5H6D8_HUMAN,tr|H0YFV6|H0YFV6_HUMAN,tr|B4DTN4|B4DTN4_HUMAN" 4 2205.1005 0.24 108377 24601 3 2206.096995 736.0408 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 4.31 3831.4 - 182233 - - - 451.9245 - 2.242 0.458 - 58.7 1 2 0 0.9965 20 0 0 0 1.91E+06 8.05E+06 - - - 5.3289 1 221125_WJC_METTL3_EV_vs_WT_F07.24603.24603.4 1.07E-11 41/240 R.LASLMNLGMSSSLNQQGAHSALSSASTSSHNLQSIFNIGSR.G "sp|P43243|MATR3_HUMAN,tr|A8MXP9|A8MXP9_HUMAN,tr|D6R991|D6R991_HUMAN,tr|D6REK4|D6REK4_HUMAN,tr|A0A0R4J2E8|A0A0R4J2E8_HUMAN,tr|D6RCM3|D6RCM3_HUMAN,tr|D6R8Z5|D6R8Z5_HUMAN,tr|D6REM6|D6REM6_HUMAN" 8 4203.0437 2.06 108379 24603 4 4203.042925 1051.7682 Matrin-3 OS=Homo sapiens OX=9606 GN=MATR3 PE=1 SV=2 9.76 3831.5 - 2.00E+06 - - - -0.1853 - 6.517 0.667 - 673.8 1 2 0 -0.0008 41 0 0 0 2.34E+08 1.13E+08 - - - 5.5698 1 221125_WJC_METTL3_EV_vs_WT_F07.24617.24617.4 4.49E-08 18/144 R.HPVEELLDSYHNQVELALQIENQHR.A sp|O00443|P3C2A_HUMAN 1 3010.4897 2.71 108384 24617 4 3010.484463 753.6297 Phosphatidylinositol 4-phosphate 3-kinase C2 domain-containing subunit alpha OS=Homo sapiens OX=9606 GN=PIK3C2A PE=1 SV=2 4.89 3833.5 - 912879 - - - -1.7386 - 3.488 0.595 - 149.4 1 2 0 -0.0052 25 0 0 0 5.37E+07 1.98E+07 - - - 4.8009 0.8622 221125_WJC_METTL3_EV_vs_WT_F07.24629.24629.4 0.0049 17/246 K.TQVIPTTVAAPTPAQAQITATGQQQPQAQPAQTQAPLVLQVD.G sp|P52655|TF2AA_HUMAN 1 4305.2605 - 108391 24629 4 4305.251359 1077.3224 Transcription initiation factor IIA subunit 1 OS=Homo sapiens OX=9606 GN=GTF2A1 PE=1 SV=1 4.3 3835 - 1.35E+06 - - - -2.1186 - 2.563 0.303 - 55.7 1 1 0 -0.0091 42 0 0 0 - - - - - 2.1299 1 221125_WJC_METTL3_EV_vs_WT_F07.24640.24640.4 3.44E-07 17/216 K.FTSSQTQSPTPPKPPSPSFELGLSSFPPLPGAAGNLK.T "sp|Q92615|LAR4B_HUMAN,tr|H0Y4V9|H0Y4V9_HUMAN" 2 3765.9254 2.18 108394 24640 4 3765.915503 942.4886 La-related protein 4B OS=Homo sapiens OX=9606 GN=LARP4B PE=1 SV=3 8.59 3836.6 - 1.05E+06 - - - -2.6262 - 2.424 0.664 - 61 1 2 0 -0.0099 37 0 0 0 9.17E+07 4.21E+07 - - - 5.2623 1 221125_WJC_METTL3_EV_vs_WT_F07.24641.24641.4 2.16E-14 30/198 R.LGQHVPTLHPTSEELTIAGMTFTTFDLGGHEQAR.R "sp|Q9NR31|SAR1A_HUMAN,tr|Q5SQT8|Q5SQT8_HUMAN" 2 3690.81 0.56 108395 24641 4 3690.797229 923.7098 GTP-binding protein SAR1a OS=Homo sapiens OX=9606 GN=SAR1A PE=1 SV=1 5.26 3836.8 - 566795 - - - -3.4724 - 4.93 0.714 - 416.7 1 2 0 -0.0128 34 0 0 0 2.61E+07 4.70E+07 - - - 5.9129 1 221125_WJC_METTL3_EV_vs_WT_F07.24653.24653.3 1.04E-08 36/116 F.GR[166.11]PHNVQPNWITLGNQLDGIHLLDPDVVAR[166.11].F sp|Q86U44|MTA70_HUMAN 1 3363.7703 0.001 108401 24653 3 3364.758293 1122.2641 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 5.99 3838.2 - 1.66E+06 - - - 293.7067 - 4.692 0.649 - 644.7 1 1 0 0.988 30 0 0 0 0.00E+00 6.09E+07 - - - 9.0585 0.999 221125_WJC_METTL3_EV_vs_WT_F07.24656.24656.4 0.000267 13/120 K.SNVVSSVVHPLLQLVPHLHER.R "sp|P48645|NMU_HUMAN,tr|A0A0B4J202|A0A0B4J202_HUMAN" 2 2359.3124 1.45 108402 24656 4 2359.310644 590.8354 Neuromedin-U OS=Homo sapiens OX=9606 GN=NMU PE=1 SV=1 6.78 3838.6 - 251941 - - - -0.7646 - 2.125 0.294 - 89.6 1 2 0 -0.0018 21 0 0 0 2.56E+07 1.77E+07 - - - 2.0337 1 221125_WJC_METTL3_EV_vs_WT_F07.24660.24660.4 1.65E-19 38/198 K.TQEDEEEISTSPGVSEFVSDAFDAC[160.03]NLNQEDLRK.E sp|Q96A49|SYAP1_HUMAN 1 3858.7014 4.39 108404 24660 4 3858.688133 965.6826 Synapse-associated protein 1 OS=Homo sapiens OX=9606 GN=SYAP1 PE=1 SV=1 3.76 3839.1 - 2.09E+06 - - - -3.4387 - 6.709 0.761 - 940.2 1 2 0 -0.0133 34 0 0 0 2.85E+08 6.49E+07 - - - 6.4137 1 221125_WJC_METTL3_EV_vs_WT_F07.24665.24665.3 7.00E-21 30/132 K.TQEDEEEISTSPGVSEFVSDAFDAC[160.03]NLNQEDLRK.E sp|Q96A49|SYAP1_HUMAN 1 3858.7014 2.07 108407 24665 3 3858.695639 1287.2411 Synapse-associated protein 1 OS=Homo sapiens OX=9606 GN=SYAP1 PE=1 SV=1 3.76 3839.8 - 2.32E+06 - - - -1.4935 - 5.646 0.801 - 703.9 1 2 0 -0.0058 34 0 0 0 1.79E+08 8.63E+07 - - - 11.451 1 221125_WJC_METTL3_EV_vs_WT_F07.24666.24666.4 0.000604 22/216 K.FTSSQTQSPTPPK[136.11]PPSPSFELGLSSFPPLPGAAGNLK[136.11].T "sp|Q92615|LAR4B_HUMAN,tr|H0Y4V9|H0Y4V9_HUMAN" 2 3781.9538 2 108408 24666 4 3781.947557 946.4957 La-related protein 4B OS=Homo sapiens OX=9606 GN=LARP4B PE=1 SV=3 8.59 3839.9 - 1.75E+06 - - - -1.6489 - 3.28 0.482 - 126.4 1 2 0 -0.0062 37 0 0 0 7.78E+07 3.90E+07 - - - 3.7678 1 221125_WJC_METTL3_EV_vs_WT_F07.24667.24667.3 3.18E-11 19/112 K.APLATGEDDDDEVPDLVENFDEASKNEAN.- "sp|P20290|BTF3_HUMAN,tr|A0A7I2V5Y3|A0A7I2V5Y3_HUMAN" 2 3118.3375 1.56 108409 24667 3 3118.336218 1040.4531 Transcription factor BTF3 OS=Homo sapiens OX=9606 GN=BTF3 PE=1 SV=1 3.42 3840 - 956948 - - - -0.3976 - 3.765 0.723 - 235.1 1 2 1 -0.0012 29 0 0 0 2.79E+07 1.79E+07 - - - 9.6505 1 221125_WJC_METTL3_EV_vs_WT_F07.24675.24675.3 4.02E-10 27/112 K.DIENQYETQITQIEHEVSSSGQEVQSSAK.E "sp|P35527|K1C9_HUMAN,tr|K7EQQ3|K7EQQ3_HUMAN" 2 3263.5066 999 108411 24675 3 3263.4935 1088.8428 "Keratin, type I cytoskeletal 9 OS=Homo sapiens OX=9606 GN=KRT9 PE=1 SV=3" 4.14 3841.3 - 1.31E+06 - - - -4.0107 - 5.605 0.701 - 851.4 1 2 0 -0.0131 29 0 0 0 8.30E+08 0.00E+00 - - - 10.3173 1 221125_WJC_METTL3_EV_vs_WT_F07.24682.24682.4 2.22E-08 17/102 K.STSESFIQHIVSLVHHVK.E "sp|Q9NYF8|BCLF1_HUMAN,tr|E9PKI6|E9PKI6_HUMAN,tr|A0A1W2PQ43|A0A1W2PQ43_HUMAN,tr|E9PK91|E9PK91_HUMAN,tr|E9PJA7|E9PJA7_HUMAN,tr|E9PK09|E9PK09_HUMAN,tr|E9PQN2|E9PQN2_HUMAN" 7 2047.0851 2.13 108415 24682 4 2047.080543 512.7785 Bcl-2-associated transcription factor 1 OS=Homo sapiens OX=9606 GN=BCLAF1 PE=1 SV=2 6.78 3842.2 - 1.18E+06 - - - -2.2134 - 3.174 0.567 - 166.9 1 2 0 -0.0045 18 0 0 0 4.63E+09 2.17E+09 - - - 4.5556 1 221125_WJC_METTL3_EV_vs_WT_F07.24683.24683.4 8.69E-10 18/102 K.STSESFIQHIVSLVHHVK[136.11].E "sp|Q9NYF8|BCLF1_HUMAN,tr|E9PKI6|E9PKI6_HUMAN,tr|A0A1W2PQ43|A0A1W2PQ43_HUMAN,tr|E9PK91|E9PK91_HUMAN,tr|E9PJA7|E9PJA7_HUMAN,tr|E9PK09|E9PK09_HUMAN,tr|E9PQN2|E9PQN2_HUMAN" 7 2055.0993 2.13 108416 24683 4 2055.096265 514.7821 Bcl-2-associated transcription factor 1 OS=Homo sapiens OX=9606 GN=BCLAF1 PE=1 SV=2 6.78 3842.4 - 870211 - - - -1.4642 - 3.166 0.598 - 220.6 1 2 0 -0.003 18 0 0 0 4.55E+09 2.14E+09 - - - 4.8249 1 221125_WJC_METTL3_EV_vs_WT_F07.24687.24687.4 1.33E-16 28/264 R.C[160.03]PKPASQIGC[160.03]SAPGYLPTSLAWHPQQSEVFVFGDENGTVSLVDTK.S "sp|Q9BQA1|MEP50_HUMAN,tr|H0Y711|H0Y711_HUMAN" 2 4874.332 5.56 108418 24687 4 4874.326376 1219.5903 Methylosome protein 50 OS=Homo sapiens OX=9606 GN=WDR77 PE=1 SV=1 4.75 3842.9 - 1.21E+06 - - - -1.1552 - 5.501 0.705 - 287.8 1 2 0 -0.0056 45 0 0 0 1.36E+07 2.44E+06 - - - 5.8417 1 221125_WJC_METTL3_EV_vs_WT_F07.24688.24688.4 3.65E-10 36/186 R.SDVEHEQQVTESPSLASVPTADELFDFHIGDR.V "sp|Q5VT06|CE350_HUMAN,tr|H0Y7F7|H0Y7F7_HUMAN" 2 3554.6438 3.82 108419 24688 4 3554.632703 889.6682 Centrosome-associated protein 350 OS=Homo sapiens OX=9606 GN=CEP350 PE=1 SV=1 4.07 3843 - 1.03E+06 - - - -3.108 - 6.388 0.717 - 719.8 1 2 0 -0.011 32 0 0 0 1.12E+07 2.93E+06 - - - 6.0236 1 221125_WJC_METTL3_EV_vs_WT_F07.24695.24695.4 8.45E-11 28/168 K.DIENQYETQITQIEHEVSSSGQEVQSSAK.E "sp|P35527|K1C9_HUMAN,tr|K7EQQ3|K7EQQ3_HUMAN" 2 3263.5066 1149.62 108422 24695 4 3263.498319 816.8839 "Keratin, type I cytoskeletal 9 OS=Homo sapiens OX=9606 GN=KRT9 PE=1 SV=3" 4.14 3844 - 6.30E+06 - - - -2.5341 - 5.331 0.676 - 494.5 1 2 0 -0.0083 29 0 0 0 2.20E+08 1.91E+05 - - - 5.6234 1 221125_WJC_METTL3_EV_vs_WT_F07.24713.24713.3 1.87E-06 17/68 K.STSESFIQHIVSLVHHVK[136.11].E "sp|Q9NYF8|BCLF1_HUMAN,tr|E9PKI6|E9PKI6_HUMAN,tr|A0A1W2PQ43|A0A1W2PQ43_HUMAN,tr|E9PK91|E9PK91_HUMAN,tr|E9PJA7|E9PJA7_HUMAN,tr|E9PK09|E9PK09_HUMAN,tr|E9PQN2|E9PQN2_HUMAN" 7 2055.0993 1.91 108430 24713 3 2055.095653 686.0404 Bcl-2-associated transcription factor 1 OS=Homo sapiens OX=9606 GN=BCLAF1 PE=1 SV=2 6.78 3846.2 - 2.57E+06 - - - -1.762 - 3.206 0.507 - 407.2 1 2 0 -0.0036 18 0 0 0 1.27E+09 6.63E+08 - - - 7.0926 0.9982 221125_WJC_METTL3_EV_vs_WT_F07.24714.24714.3 8.57E-07 18/60 T.SESFIQHIVSLVHHVK.E "sp|Q9NYF8|BCLF1_HUMAN,tr|E9PKI6|E9PKI6_HUMAN,tr|A0A1W2PQ43|A0A1W2PQ43_HUMAN,tr|E9PK91|E9PK91_HUMAN,tr|E9PJA7|E9PJA7_HUMAN,tr|E9PK09|E9PK09_HUMAN,tr|E9PQN2|E9PQN2_HUMAN" 7 1859.0054 2.15 108431 24714 3 1859.003921 620.6757 Bcl-2-associated transcription factor 1 OS=Homo sapiens OX=9606 GN=BCLAF1 PE=1 SV=2 6.78 3846.4 - 449863 - - - -0.7778 - 3.042 0.531 - 325 1 1 0 -0.0014 16 0 0 0 1.14E+08 5.29E+07 - - - 7.3143 0.907 221125_WJC_METTL3_EV_vs_WT_F07.24716.24716.2 0.000307 22-Oct K.K[136.11]VSQEILELLNT.T "sp|Q86U44|MTA70_HUMAN,tr|H0YFV6|H0YFV6_HUMAN" 2 1393.7908 0.001 108433 24716 2 1393.786067 697.9027 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 4.53 3846.6 - 555698 - - - -3.3929 - 2.134 0.352 - 389.9 1 1 0 -0.0047 12 0 0 0 0.00E+00 8.13E+06 - - - 3.6338 1 221125_WJC_METTL3_EV_vs_WT_F07.24722.24722.3 2.13E-07 24/44 F.IQHIVSLVHHVK.E "sp|Q9NYF8|BCLF1_HUMAN,tr|E9PKI6|E9PKI6_HUMAN,tr|A0A1W2PQ43|A0A1W2PQ43_HUMAN,tr|E9PK91|E9PK91_HUMAN,tr|E9PJA7|E9PJA7_HUMAN,tr|E9PK09|E9PK09_HUMAN,tr|E9PQN2|E9PQN2_HUMAN" 7 1408.8303 2.22 108434 24722 3 1408.831442 470.6174 Bcl-2-associated transcription factor 1 OS=Homo sapiens OX=9606 GN=BCLAF1 PE=1 SV=2 8.77 3847.5 - 2.77E+06 - - - 0.8085 - 3.438 0.598 - 731.3 1 1 0 0.0011 12 0 0 0 6.57E+07 2.96E+07 - - - 8.6297 0.9723 221125_WJC_METTL3_EV_vs_WT_F07.24726.24726.3 4.15E-05 16/60 T.SESFIQHIVSLVHHVK[136.11].E "sp|Q9NYF8|BCLF1_HUMAN,tr|E9PKI6|E9PKI6_HUMAN,tr|A0A1W2PQ43|A0A1W2PQ43_HUMAN,tr|E9PK91|E9PK91_HUMAN,tr|E9PJA7|E9PJA7_HUMAN,tr|E9PK09|E9PK09_HUMAN,tr|E9PQN2|E9PQN2_HUMAN" 7 1867.0196 2.15 108437 24726 3 1867.013888 623.3471 Bcl-2-associated transcription factor 1 OS=Homo sapiens OX=9606 GN=BCLAF1 PE=1 SV=2 6.78 3848 - 994116 - - - -3.0417 - 2.686 0.401 - 249 1 1 0 -0.0057 16 0 0 0 1.13E+08 5.26E+07 - - - 5.5444 0.9946 221125_WJC_METTL3_EV_vs_WT_F07.24729.24729.3 6.02E-07 19/48 S.FIQHIVSLVHHVK.E "sp|Q9NYF8|BCLF1_HUMAN,tr|E9PKI6|E9PKI6_HUMAN,tr|A0A1W2PQ43|A0A1W2PQ43_HUMAN,tr|E9PK91|E9PK91_HUMAN,tr|E9PJA7|E9PJA7_HUMAN,tr|E9PK09|E9PK09_HUMAN,tr|E9PQN2|E9PQN2_HUMAN" 7 1555.8987 2.21 108438 24729 3 1555.894749 519.6402 Bcl-2-associated transcription factor 1 OS=Homo sapiens OX=9606 GN=BCLAF1 PE=1 SV=2 8.77 3848.4 - 189016 - - - -2.5503 - 2.723 0.527 - 455.6 1 1 0 -0.004 13 0 0 0 2.42E+07 1.10E+07 - - - 7.1304 0.9987 221125_WJC_METTL3_EV_vs_WT_F07.24732.24732.3 1.07E-05 23/44 F.IQHIVSLVHHVK[136.11].E "sp|Q9NYF8|BCLF1_HUMAN,tr|E9PKI6|E9PKI6_HUMAN,tr|A0A1W2PQ43|A0A1W2PQ43_HUMAN,tr|E9PK91|E9PK91_HUMAN,tr|E9PJA7|E9PJA7_HUMAN,tr|E9PK09|E9PK09_HUMAN,tr|E9PQN2|E9PQN2_HUMAN" 7 1416.8445 2.2 108439 24732 3 1416.842825 473.2888 Bcl-2-associated transcription factor 1 OS=Homo sapiens OX=9606 GN=BCLAF1 PE=1 SV=2 8.77 3848.8 - 478941 - - - -1.1843 - 3.435 0.545 - 691 1 1 0 -0.0017 12 0 0 0 6.42E+07 2.92E+07 - - - 8.0363 1 221125_WJC_METTL3_EV_vs_WT_F07.24736.24736.3 1.24E-09 21/68 K.STSESFIQHIVSLVHHVK.E "sp|Q9NYF8|BCLF1_HUMAN,tr|E9PKI6|E9PKI6_HUMAN,tr|A0A1W2PQ43|A0A1W2PQ43_HUMAN,tr|E9PK91|E9PK91_HUMAN,tr|E9PJA7|E9PJA7_HUMAN,tr|E9PK09|E9PK09_HUMAN,tr|E9PQN2|E9PQN2_HUMAN" 7 2047.0851 1.91 108441 24736 3 2047.079762 683.369 Bcl-2-associated transcription factor 1 OS=Homo sapiens OX=9606 GN=BCLAF1 PE=1 SV=2 6.78 3849.3 - 2.48E+07 - - - -2.5949 - 3.698 0.592 - 574 1 2 0 -0.0053 18 0 0 0 1.25E+09 6.53E+08 - - - 8.3953 0.9009 221125_WJC_METTL3_EV_vs_WT_F07.24742.24742.2 1.11E-10 18/36 L.TLGNQLDGIHLLDPDVVAR[166.11].F sp|Q86U44|MTA70_HUMAN 1 2055.0988 0.03 108445 24742 2 2055.095419 1028.5567 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 4.41 3850.1 - 333020 - - - -1.6564 - 3.113 0.065 - 549.4 1 1 0 -0.0034 19 0 0 0 4.34E+05 1.43E+07 - - - 2.3119 0.9973 221125_WJC_METTL3_EV_vs_WT_F07.24744.24744.3 5.82E-07 16/48 S.FIQHIVSLVHHVK[136.11].E "sp|Q9NYF8|BCLF1_HUMAN,tr|E9PKI6|E9PKI6_HUMAN,tr|A0A1W2PQ43|A0A1W2PQ43_HUMAN,tr|E9PK91|E9PK91_HUMAN,tr|E9PJA7|E9PJA7_HUMAN,tr|E9PK09|E9PK09_HUMAN,tr|E9PQN2|E9PQN2_HUMAN" 7 1563.9129 2.2 108447 24744 3 1563.909528 522.3116 Bcl-2-associated transcription factor 1 OS=Homo sapiens OX=9606 GN=BCLAF1 PE=1 SV=2 8.77 3850.3 - 480610 - - - -2.167 - 3.063 0.561 - 277.2 1 1 0 -0.0034 13 0 0 0 2.37E+07 1.08E+07 - - - 7.8287 0.9923 221125_WJC_METTL3_EV_vs_WT_F07.24758.24758.4 6.24E-08 18/96 T.RTHNLEPYFESFINNLR.R sp|P04264|K2C1_HUMAN 1 2149.0705 27.01 108452 24758 4 2149.063349 538.2749 "Keratin, type II cytoskeletal 1 OS=Homo sapiens OX=9606 GN=KRT1 PE=1 SV=6" 6.76 3852.2 - 292666 - - - -3.3214 - 3.146 0.576 - 325.8 1 1 0 -0.0071 17 0 0 0 3.92E+07 1.45E+06 - - - 4.6355 1 221125_WJC_METTL3_EV_vs_WT_F07.24760.24760.2 1.05E-13 24/34 K.STSESFIQHIVSLVHHVK.E "sp|Q9NYF8|BCLF1_HUMAN,tr|E9PKI6|E9PKI6_HUMAN,tr|A0A1W2PQ43|A0A1W2PQ43_HUMAN,tr|E9PK91|E9PK91_HUMAN,tr|E9PJA7|E9PJA7_HUMAN,tr|E9PK09|E9PK09_HUMAN,tr|E9PQN2|E9PQN2_HUMAN" 7 2047.0851 1.35 108453 24760 2 2047.076611 1024.5498 Bcl-2-associated transcription factor 1 OS=Homo sapiens OX=9606 GN=BCLAF1 PE=1 SV=2 6.78 3852.4 - 284989 - - - -4.1342 - 4.123 0.711 - 1827.8 1 2 0 -0.0085 18 0 0 0 1.98E+07 1.46E+07 - - - 7.7725 0.99 221125_WJC_METTL3_EV_vs_WT_F07.24761.24761.3 4.00E-06 22/52 E.SFIQHIVSLVHHVK.E "sp|Q9NYF8|BCLF1_HUMAN,tr|E9PKI6|E9PKI6_HUMAN,tr|A0A1W2PQ43|A0A1W2PQ43_HUMAN,tr|E9PK91|E9PK91_HUMAN,tr|E9PJA7|E9PJA7_HUMAN,tr|E9PK09|E9PK09_HUMAN,tr|E9PQN2|E9PQN2_HUMAN" 7 1642.9307 2.13 108454 24761 3 1642.924116 548.6509 Bcl-2-associated transcription factor 1 OS=Homo sapiens OX=9606 GN=BCLAF1 PE=1 SV=2 8.53 3852.5 - 210353 - - - -4.0355 - 3.77 0.524 - 441.9 1 1 0 -0.0066 14 0 0 0 1.82E+07 8.56E+06 - - - 7.907 0.9951 221125_WJC_METTL3_EV_vs_WT_F07.24763.24763.3 9.42E-08 17/56 S.ESFIQHIVSLVHHVK.E "sp|Q9NYF8|BCLF1_HUMAN,tr|E9PKI6|E9PKI6_HUMAN,tr|A0A1W2PQ43|A0A1W2PQ43_HUMAN,tr|E9PK91|E9PK91_HUMAN,tr|E9PJA7|E9PJA7_HUMAN,tr|E9PK09|E9PK09_HUMAN,tr|E9PQN2|E9PQN2_HUMAN" 7 1771.9733 1.57 108456 24763 3 1771.97038 591.6651 Bcl-2-associated transcription factor 1 OS=Homo sapiens OX=9606 GN=BCLAF1 PE=1 SV=2 7.11 3852.8 - 692555 - - - -1.6699 - 2.921 0.455 - 338.3 1 1 0 -0.003 15 0 0 0 1.87E+07 1.19E+07 - - - 6.409 0.9845 221125_WJC_METTL3_EV_vs_WT_F07.24765.24765.3 0.000373 14/52 E.SFIQHIVSLVHHVK[136.11].E "sp|Q9NYF8|BCLF1_HUMAN,tr|E9PKI6|E9PKI6_HUMAN,tr|A0A1W2PQ43|A0A1W2PQ43_HUMAN,tr|E9PK91|E9PK91_HUMAN,tr|E9PJA7|E9PJA7_HUMAN,tr|E9PK09|E9PK09_HUMAN,tr|E9PQN2|E9PQN2_HUMAN" 7 1650.9449 2.12 108458 24765 3 1650.939984 551.3223 Bcl-2-associated transcription factor 1 OS=Homo sapiens OX=9606 GN=BCLAF1 PE=1 SV=2 8.53 3853.1 - 0 - - - -3.0056 - 2.826 0.436 - 176.1 1 1 0 -0.005 14 0 0 0 1.87E+07 8.84E+06 - - - 6.1604 1 221125_WJC_METTL3_EV_vs_WT_F07.24768.24768.4 9.77E-13 34/258 K.AQSGLAFQQTSNTQPIPILYEHQLGQASGLGGSQLIDTHLLQAR.A "sp|Q9Y520|PRC2C_HUMAN,tr|E7EPN9|E7EPN9_HUMAN,tr|H7C5N8|H7C5N8_HUMAN,tr|A0A2R8Y7F4|A0A2R8Y7F4_HUMAN,tr|A0A2R8YET2|A0A2R8YET2_HUMAN" 5 4686.4154 3.73 108459 24768 4 4686.39931 1172.6111 Protein PRRC2C OS=Homo sapiens OX=9606 GN=PRRC2C PE=1 SV=4 6 3853.5 - 1.02E+06 - - - -3.437 - 6.757 0.706 - 346.4 1 2 0 -0.0161 44 0 0 0 1.11E+07 2.97E+06 - - - 5.9079 0.9969 221125_WJC_METTL3_EV_vs_WT_F07.24769.24769.4 2.86E-07 16/96 S.TSESFIQHIVSLVHHVK.E "sp|Q9NYF8|BCLF1_HUMAN,tr|E9PKI6|E9PKI6_HUMAN,tr|A0A1W2PQ43|A0A1W2PQ43_HUMAN,tr|E9PK91|E9PK91_HUMAN,tr|E9PJA7|E9PJA7_HUMAN,tr|E9PK09|E9PK09_HUMAN,tr|E9PQN2|E9PQN2_HUMAN" 7 1960.053 2.22 108460 24769 4 1960.048589 491.0205 Bcl-2-associated transcription factor 1 OS=Homo sapiens OX=9606 GN=BCLAF1 PE=1 SV=2 6.74 3853.6 - 647691 - - - -2.2739 - 2.892 0.603 - 177.5 1 1 0 -0.0045 17 0 0 0 2.39E+07 1.08E+07 - - - 4.842 0.9301 221125_WJC_METTL3_EV_vs_WT_F07.24770.24770.4 0.00278 Dec-90 T.SESFIQHIVSLVHHVK.E "sp|Q9NYF8|BCLF1_HUMAN,tr|E9PKI6|E9PKI6_HUMAN,tr|A0A1W2PQ43|A0A1W2PQ43_HUMAN,tr|E9PK91|E9PK91_HUMAN,tr|E9PJA7|E9PJA7_HUMAN,tr|E9PK09|E9PK09_HUMAN,tr|E9PQN2|E9PQN2_HUMAN" 7 1859.0054 2.33 108461 24770 4 1858.99601 465.7586 Bcl-2-associated transcription factor 1 OS=Homo sapiens OX=9606 GN=BCLAF1 PE=1 SV=2 6.78 3853.7 - 335094 - - - -5.0333 - 2.225 0.481 - 51.2 1 1 0 -0.0094 16 0 0 0 9.37E+06 4.03E+06 - - - 3.6918 0.9907 221125_WJC_METTL3_EV_vs_WT_F07.24772.24772.3 8.58E-08 21/64 T.RTHNLEPYFESFINNLR.R sp|P04264|K2C1_HUMAN 1 2149.0705 999 108463 24772 3 2149.062265 717.3641 "Keratin, type II cytoskeletal 1 OS=Homo sapiens OX=9606 GN=KRT1 PE=1 SV=6" 6.76 3854 - 264627 - - - -3.8258 - 3.732 0.528 - 816.8 1 1 0 -0.0082 17 0 0 0 2.72E+07 0.00E+00 - - - 7.7514 0.8744 221125_WJC_METTL3_EV_vs_WT_F07.24773.24773.3 5.69E-06 13/56 S.ESFIQHIVSLVHHVK[136.11].E "sp|Q9NYF8|BCLF1_HUMAN,tr|E9PKI6|E9PKI6_HUMAN,tr|A0A1W2PQ43|A0A1W2PQ43_HUMAN,tr|E9PK91|E9PK91_HUMAN,tr|E9PJA7|E9PJA7_HUMAN,tr|E9PK09|E9PK09_HUMAN,tr|E9PQN2|E9PQN2_HUMAN" 7 1779.9875 1.34 108464 24773 3 1779.976278 594.3365 Bcl-2-associated transcription factor 1 OS=Homo sapiens OX=9606 GN=BCLAF1 PE=1 SV=2 7.11 3854.1 - 234599 - - - -6.3264 - 2.608 0.478 - 345.8 1 1 0 -0.0113 15 0 0 0 1.89E+07 1.41E+07 - - - 6.3674 0.9971 221125_WJC_METTL3_EV_vs_WT_F07.24778.24778.3 5.46E-10 17/64 S.TSESFIQHIVSLVHHVK.E "sp|Q9NYF8|BCLF1_HUMAN,tr|E9PKI6|E9PKI6_HUMAN,tr|A0A1W2PQ43|A0A1W2PQ43_HUMAN,tr|E9PK91|E9PK91_HUMAN,tr|E9PJA7|E9PJA7_HUMAN,tr|E9PK09|E9PK09_HUMAN,tr|E9PQN2|E9PQN2_HUMAN" 7 1960.053 3.18 108466 24778 3 1960.04782 654.3583 Bcl-2-associated transcription factor 1 OS=Homo sapiens OX=9606 GN=BCLAF1 PE=1 SV=2 6.74 3854.8 - 505495 - - - -2.6663 - 3.201 0.622 - 360.1 1 1 0 -0.0052 17 0 0 0 1.52E+07 4.77E+06 - - - 8.4125 1 221125_WJC_METTL3_EV_vs_WT_F07.24779.24779.2 8.37E-05 15/18 Q.HIVSLVHHVK[136.11].E "sp|Q9NYF8|BCLF1_HUMAN,tr|E9PKI6|E9PKI6_HUMAN,tr|A0A1W2PQ43|A0A1W2PQ43_HUMAN,tr|E9PK91|E9PK91_HUMAN,tr|E9PJA7|E9PJA7_HUMAN,tr|E9PK09|E9PK09_HUMAN,tr|E9PQN2|E9PQN2_HUMAN" 7 1175.7019 6.6 108467 24779 2 1175.702545 588.8582 Bcl-2-associated transcription factor 1 OS=Homo sapiens OX=9606 GN=BCLAF1 PE=1 SV=2 8.77 3854.9 - 66140.3 - - - 0.5809 - 2.679 0.556 - 652.2 1 1 0 0.0007 10 0 0 0 6.35E+06 9.61E+05 - - - 5.8981 1 221125_WJC_METTL3_EV_vs_WT_F07.24794.24794.4 1.06E-12 30/168 K.SR[166.11]QELEQHSVDTASTSDAVTFITYVQSLK[136.11].R "sp|Q14204|DYHC1_HUMAN,tr|A0A7P0T8N2|A0A7P0T8N2_HUMAN,tr|A0A7P0T9C4|A0A7P0T9C4_HUMAN,tr|A0A7P0TBJ7|A0A7P0TBJ7_HUMAN,tr|A0A804HHY6|A0A804HHY6_HUMAN,tr|A0A7P0T9K2|A0A7P0T9K2_HUMAN,tr|A0A7P0TB64|A0A7P0TB64_HUMAN,tr|A0A2R8Y706|A0A2R8Y706_HUMAN,tr|A0A7P0T916|A0A7P0T916_HUMAN,tr|A0A7P0TB75|A0A7P0TB75_HUMAN,tr|A0A7P0T8W5|A0A7P0T8W5_HUMAN,tr|A0A7P0T9S3|A0A7P0T9S3_HUMAN,tr|A0A7P0TAF3|A0A7P0TAF3_HUMAN,tr|A0A7P0T9F1|A0A7P0T9F1_HUMAN,tr|A0A7P0TAW9|A0A7P0TAW9_HUMAN,tr|A0A2R8YGC7|A0A2R8YGC7_HUMAN,tr|A0A7P0TA13|A0A7P0TA13_HUMAN,tr|A0A7P0T934|A0A7P0T934_HUMAN,tr|A0A7P0TAV5|A0A7P0TAV5_HUMAN,tr|A0A7P0T9Y3|A0A7P0T9Y3_HUMAN,tr|A0A7P0T7V5|A0A7P0T7V5_HUMAN,tr|A0A7P0T9R4|A0A7P0T9R4_HUMAN,tr|A0A2R8Y5T0|A0A2R8Y5T0_HUMAN,tr|A0A7P0T990|A0A7P0T990_HUMAN,tr|A0A7P0T942|A0A7P0T942_HUMAN,tr|A0A2R8YFZ7|A0A2R8YFZ7_HUMAN,tr|A0A7P0T825|A0A7P0T825_HUMAN,tr|A0A2R8Y6H2|A0A2R8Y6H2_HUMAN,tr|A0A7P0TBC9|A0A7P0TBC9_HUMAN,tr|A0A7P0TAM4|A0A7P0TAM4_HUMAN" 30 3257.6171 0.76 108475 24794 4 3257.611212 815.4115 Cytoplasmic dynein 1 heavy chain 1 OS=Homo sapiens OX=9606 GN=DYNC1H1 PE=1 SV=5 4.75 3857 - 1.46E+06 - - - -1.8032 - 5.09 0.668 - 605.1 1 2 1 -0.0059 29 0 0 0 3.21E+07 4.20E+07 - - - 5.5402 0.9998 221125_WJC_METTL3_EV_vs_WT_F07.24795.24795.4 0.0961 12/132 R.GFGFVTYATVEEVDAAMNARPHK.V "sp|P09651|ROA1_HUMAN,tr|A0A7I2YQX9|A0A7I2YQX9_HUMAN,tr|A0A7I2V3W4|A0A7I2V3W4_HUMAN,tr|F8W646|F8W646_HUMAN,tr|F8VZ49|F8VZ49_HUMAN,tr|A0A7I2V3R8|A0A7I2V3R8_HUMAN,tr|F8W6I7|F8W6I7_HUMAN,tr|F8VYN5|F8VYN5_HUMAN,tr|A0A7I2V2L6|A0A7I2V2L6_HUMAN,tr|A0A7I2V3C7|A0A7I2V3C7_HUMAN,tr|A0A7I2V3W0|A0A7I2V3W0_HUMAN,tr|A0A7I2YQV3|A0A7I2YQV3_HUMAN,tr|A0A2R8Y4L2|A0A2R8Y4L2_HUMAN,tr|A0A7I2V2Z4|A0A7I2V2Z4_HUMAN,tr|A0A7I2V4M0|A0A7I2V4M0_HUMAN" 15 2509.206 1.34 108476 24795 4 2509.202956 628.3088 Heterogeneous nuclear ribonucleoprotein A1 OS=Homo sapiens OX=9606 GN=HNRNPA1 PE=1 SV=5 5.45 3857.2 - 316577 - - - -1.2107 - 2.498 0.374 - 69.6 1 2 0 -0.003 23 0 0 0 5.75E+06 4.29E+06 - - - 2.7771 0.9999 221125_WJC_METTL3_EV_vs_WT_F07.24799.24799.4 6.69E-13 33/168 K.SRQELEQHSVDTASTSDAVTFITYVQSLK.R "sp|Q14204|DYHC1_HUMAN,tr|A0A7P0T8N2|A0A7P0T8N2_HUMAN,tr|A0A7P0T9C4|A0A7P0T9C4_HUMAN,tr|A0A7P0TBJ7|A0A7P0TBJ7_HUMAN,tr|A0A804HHY6|A0A804HHY6_HUMAN,tr|A0A7P0T9K2|A0A7P0T9K2_HUMAN,tr|A0A7P0TB64|A0A7P0TB64_HUMAN,tr|A0A2R8Y706|A0A2R8Y706_HUMAN,tr|A0A7P0T916|A0A7P0T916_HUMAN,tr|A0A7P0TB75|A0A7P0TB75_HUMAN,tr|A0A7P0T8W5|A0A7P0T8W5_HUMAN,tr|A0A7P0T9S3|A0A7P0T9S3_HUMAN,tr|A0A7P0TAF3|A0A7P0TAF3_HUMAN,tr|A0A7P0T9F1|A0A7P0T9F1_HUMAN,tr|A0A7P0TAW9|A0A7P0TAW9_HUMAN,tr|A0A2R8YGC7|A0A2R8YGC7_HUMAN,tr|A0A7P0TA13|A0A7P0TA13_HUMAN,tr|A0A7P0T934|A0A7P0T934_HUMAN,tr|A0A7P0TAV5|A0A7P0TAV5_HUMAN,tr|A0A7P0T9Y3|A0A7P0T9Y3_HUMAN,tr|A0A7P0T7V5|A0A7P0T7V5_HUMAN,tr|A0A7P0T9R4|A0A7P0T9R4_HUMAN,tr|A0A2R8Y5T0|A0A2R8Y5T0_HUMAN,tr|A0A7P0T990|A0A7P0T990_HUMAN,tr|A0A7P0T942|A0A7P0T942_HUMAN,tr|A0A2R8YFZ7|A0A2R8YFZ7_HUMAN,tr|A0A7P0T825|A0A7P0T825_HUMAN,tr|A0A2R8Y6H2|A0A2R8Y6H2_HUMAN,tr|A0A7P0TBC9|A0A7P0TBC9_HUMAN,tr|A0A7P0TAM4|A0A7P0TAM4_HUMAN" 30 3239.5946 0.76 108477 24799 4 3239.589944 810.9059 Cytoplasmic dynein 1 heavy chain 1 OS=Homo sapiens OX=9606 GN=DYNC1H1 PE=1 SV=5 4.75 3857.7 - 2.24E+06 - - - -1.4422 - 4.214 0.597 - 499 1 2 1 -0.0047 29 0 0 0 2.94E+07 3.87E+07 - - - 4.8643 0.9856 221125_WJC_METTL3_EV_vs_WT_F07.24802.24802.2 0.000474 20-Sep L.QHIVSLVHHVK.E "sp|Q9NYF8|BCLF1_HUMAN,tr|E9PKI6|E9PKI6_HUMAN,tr|A0A1W2PQ43|A0A1W2PQ43_HUMAN,tr|E9PK91|E9PK91_HUMAN,tr|E9PJA7|E9PJA7_HUMAN,tr|E9PK09|E9PK09_HUMAN,tr|E9PQN2|E9PQN2_HUMAN" 7 1295.7462 38.38 108479 24802 2 1295.745177 648.8804 Bcl-2-associated transcription factor 1 OS=Homo sapiens OX=9606 GN=BCLAF1 PE=1 SV=2 8.77 3858.1 - 101546 - - - -0.8196 - 1.723 0.468 - 218.1 1 1 0 -0.0011 11 0 0 0 2.01E+06 5.25E+04 - - - 3.9691 1 221125_WJC_METTL3_EV_vs_WT_F07.24808.24808.2 5.22E-13 21/32 L.GNQLDGIHLLDPDVVAR[166.11].F sp|Q86U44|MTA70_HUMAN 1 1840.9671 0.001 108482 24808 2 1840.972452 921.4908 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 4.41 3858.9 - 184853 - - - 2.9175 - 3.748 0.686 - 841.9 1 1 0 0.0054 17 0 0 0 0.00E+00 4.00E+06 - - - 7.3544 0.9998 221125_WJC_METTL3_EV_vs_WT_F07.24811.24811.2 4.41E-06 24-Dec K.TLNDELEIIEGMK[136.11].F "sp|P10809|CH60_HUMAN,tr|A0A7I2V2X6|A0A7I2V2X6_HUMAN,tr|A0A7I2V599|A0A7I2V599_HUMAN,tr|E7EXB4|E7EXB4_HUMAN,tr|A0A7I2YQ71|A0A7I2YQ71_HUMAN,tr|E7ESH4|E7ESH4_HUMAN,tr|A0A7I2V5M1|A0A7I2V5M1_HUMAN,tr|A0A7I2V5K3|A0A7I2V5K3_HUMAN,tr|A0A7I2V369|A0A7I2V369_HUMAN" 9 1511.7633 1.39 108483 24811 2 1511.760286 756.8889 "60 kDa heat shock protein, mitochondrial OS=Homo sapiens OX=9606 GN=HSPD1 PE=1 SV=2" 4 3859.3 - 285031 - - - -1.9679 - 2.499 0.581 - 312.7 1 2 0 -0.003 13 0 0 0 9.45E+06 6.79E+06 - - - 5.682 0.9998 221125_WJC_METTL3_EV_vs_WT_F07.24812.24812.4 9.75E-05 12/132 R.GFGFVTYATVEEVDAAMNAR[166.11]PHK[136.11].V "sp|P09651|ROA1_HUMAN,tr|A0A7I2YQX9|A0A7I2YQX9_HUMAN,tr|A0A7I2V3W4|A0A7I2V3W4_HUMAN,tr|F8W646|F8W646_HUMAN,tr|F8VZ49|F8VZ49_HUMAN,tr|A0A7I2V3R8|A0A7I2V3R8_HUMAN,tr|F8W6I7|F8W6I7_HUMAN,tr|F8VYN5|F8VYN5_HUMAN,tr|A0A7I2V2L6|A0A7I2V2L6_HUMAN,tr|A0A7I2V3C7|A0A7I2V3C7_HUMAN,tr|A0A7I2V3W0|A0A7I2V3W0_HUMAN,tr|A0A7I2YQV3|A0A7I2YQV3_HUMAN,tr|A0A2R8Y4L2|A0A2R8Y4L2_HUMAN,tr|A0A7I2V2Z4|A0A7I2V2Z4_HUMAN,tr|A0A7I2V4M0|A0A7I2V4M0_HUMAN" 15 2527.2285 1.39 108484 24812 4 2527.221687 632.8144 Heterogeneous nuclear ribonucleoprotein A1 OS=Homo sapiens OX=9606 GN=HNRNPA1 PE=1 SV=5 5.45 3859.4 - 323488 - - - -2.6816 - 2.11 0.438 - 81.9 1 2 0 -0.0068 23 0 0 0 5.70E+06 4.09E+06 - - - 3.2784 1 221125_WJC_METTL3_EV_vs_WT_F07.24813.24813.4 2.05E-10 18/240 R.YR[166.11]APGEQDGDAMPLGSAVDILATDDPNFSQEDQQDTQIYEK[136.11].H "sp|P25205|MCM3_HUMAN,tr|Q7Z6P5|Q7Z6P5_HUMAN,tr|J3KQ69|J3KQ69_HUMAN,tr|A0A499FHX9|A0A499FHX9_HUMAN" 4 4545.0521 0.42 108485 24813 4 4545.023948 1137.2703 DNA replication licensing factor MCM3 OS=Homo sapiens OX=9606 GN=MCM3 PE=1 SV=3 3.66 3859.6 - 284608 - - - -6.1902 - 3.777 0.664 - 97 1 2 1 -0.0281 41 0 0 0 7.94E+05 1.87E+06 - - - 5.3794 1 221125_WJC_METTL3_EV_vs_WT_F07.24833.24833.4 1.76E-08 35/192 R.VEMEDAHTAVVGIPHGLEDWSFFAVYDGHAGSR.V "sp|O75688|PPM1B_HUMAN,tr|B8ZZF0|B8ZZF0_HUMAN,tr|A0A3B3IS24|A0A3B3IS24_HUMAN,tr|C9JIR6|C9JIR6_HUMAN" 4 3598.6576 4.61 108491 24833 4 3598.650339 900.6717 Protein phosphatase 1B OS=Homo sapiens OX=9606 GN=PPM1B PE=1 SV=1 4.56 3862.3 - 2.22E+06 - - - -2.0085 - 5.791 0.695 - 572.5 1 2 0 -0.0072 33 0 0 0 7.74E+06 1.68E+06 - - - 5.8002 0.9787 221125_WJC_METTL3_EV_vs_WT_F07.24848.24848.4 0.00865 7/114 M.TKLEEHLEGIVNIFHQYSVR.K sp|P80511|S10AC_HUMAN 1 2411.2597 999 108498 24848 4 2411.254776 603.8222 Protein S100-A12 OS=Homo sapiens OX=9606 GN=S100A12 PE=1 SV=2 5.96 3864.4 - 0 - - - -2.0603 - 1.707 0.246 - 23.8 1 2 1 -0.005 20 0 0 0 3.17E+06 0.00E+00 - - - 1.5446 0.9914 221125_WJC_METTL3_EV_vs_WT_F07.24863.24863.3 1.81E-08 16/120 R.TTPPEAAQNGQSPMAALILVADNAGGSHASK.D sp|Q7Z5L9|I2BP2_HUMAN 1 3003.472 -1 108504 24863 3 3004.46014 1002.1646 Interferon regulatory factor 2-binding protein 2 OS=Homo sapiens OX=9606 GN=IRF2BP2 PE=1 SV=2 5.29 3866.4 - 564471 - - - 328.9999 - 2.825 0.59 - 184.6 1 2 0 0.9881 31 0 0 0 0.00E+00 0.00E+00 - - - 7.2334 0.9994 221125_WJC_METTL3_EV_vs_WT_F07.24886.24886.4 0.0102 12/114 K.LSSSIIHEIDSILGNK[136.11]PYSK[136.11].K "sp|Q13303|KCAB2_HUMAN,tr|A0A5F9UN28|A0A5F9UN28_HUMAN,tr|A0A590UJB6|A0A590UJB6_HUMAN" 3 2216.2023 1.91 108515 24886 4 2216.19974 555.0579 Voltage-gated potassium channel subunit beta-2 OS=Homo sapiens OX=9606 GN=KCNAB2 PE=1 SV=2 6.75 3869.4 - 318324 - - - -1.1772 - 1.801 0.325 - 102 1 2 0 -0.0026 20 0 0 0 2.36E+07 1.24E+07 - - - 2.2508 0.9961 221125_WJC_METTL3_EV_vs_WT_F07.24890.24890.4 0.0014 8/108 R.ADLEMQIENLKEELAYLKK.N "sp|Q04695|K1C17_HUMAN,tr|K7EPJ9|K7EPJ9_HUMAN,tr|F5GWP8|F5GWP8_HUMAN" 3 2277.1926 1.26 108516 24890 4 2277.198021 570.3054 "Keratin, type I cytoskeletal 17 OS=Homo sapiens OX=9606 GN=KRT17 PE=1 SV=2" 4.59 3870 - 31789.3 - - - 2.3652 - 1.638 0.342 - 37.3 1 2 1 0.0054 19 0 0 0 9.22E+06 7.32E+06 - - - 2.3682 0.9487 221125_WJC_METTL3_EV_vs_WT_F07.24891.24891.4 0.0129 7/108 R.GLLQDDAHPTLVTYADHSK[136.11].L "sp|Q86U44|MTA70_HUMAN,tr|F5H6D8|F5H6D8_HUMAN,tr|H0YFV6|H0YFV6_HUMAN,tr|B4DTN4|B4DTN4_HUMAN" 4 2088.0367 0 108517 24891 4 2089.039047 523.0165 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 5.13 3870.1 - 156347 - - - 480.027 - 1.53 0.299 - 44.6 1 2 0 1.0023 19 0 0 0 5.60E+04 1.63E+07 - - - 1.6947 1 221125_WJC_METTL3_EV_vs_WT_F07.24906.24906.4 5.58E-09 20/102 K.STSESFIQHIVSLVHHVK.E "sp|Q9NYF8|BCLF1_HUMAN,tr|E9PKI6|E9PKI6_HUMAN,tr|A0A1W2PQ43|A0A1W2PQ43_HUMAN,tr|E9PK91|E9PK91_HUMAN,tr|E9PJA7|E9PJA7_HUMAN,tr|E9PK09|E9PK09_HUMAN,tr|E9PQN2|E9PQN2_HUMAN" 7 2047.0851 2.18 108523 24906 4 2047.088484 512.7785 Bcl-2-associated transcription factor 1 OS=Homo sapiens OX=9606 GN=BCLAF1 PE=1 SV=2 6.78 3872.2 - 1.92E+07 - - - 1.6658 - 3.828 0.64 - 241.2 1 2 0 0.0034 18 0 0 0 2.89E+09 1.33E+09 - - - 5.2554 1 221125_WJC_METTL3_EV_vs_WT_F07.24909.24909.4 9.14E-10 12/102 K.STSESFIQHIVSLVHHVK[136.11].E "sp|Q9NYF8|BCLF1_HUMAN,tr|E9PKI6|E9PKI6_HUMAN,tr|A0A1W2PQ43|A0A1W2PQ43_HUMAN,tr|E9PK91|E9PK91_HUMAN,tr|E9PJA7|E9PJA7_HUMAN,tr|E9PK09|E9PK09_HUMAN,tr|E9PQN2|E9PQN2_HUMAN" 7 2055.0993 2.18 108525 24909 4 2055.097213 514.7821 Bcl-2-associated transcription factor 1 OS=Homo sapiens OX=9606 GN=BCLAF1 PE=1 SV=2 6.78 3872.6 - 3.99E+06 - - - -1.0029 - 2.659 0.605 - 97.4 1 2 0 -0.0021 18 0 0 0 2.96E+09 1.36E+09 - - - 4.8264 0.9999 221125_WJC_METTL3_EV_vs_WT_F07.24919.24919.3 1.46E-05 Nov-76 K.LSSSIIHEIDSILGNK[136.11]PYSK[136.11].K "sp|Q13303|KCAB2_HUMAN,tr|A0A5F9UN28|A0A5F9UN28_HUMAN,tr|A0A590UJB6|A0A590UJB6_HUMAN" 3 2216.2023 1.18 108529 24919 3 2216.204431 739.7414 Voltage-gated potassium channel subunit beta-2 OS=Homo sapiens OX=9606 GN=KCNAB2 PE=1 SV=2 6.75 3873.9 - 193412 - - - 0.9394 - 1.971 0.485 - 98.1 1 2 0 0.0021 20 0 0 0 6.04E+06 5.12E+06 - - - 5.5928 0.9999 221125_WJC_METTL3_EV_vs_WT_F07.24920.24920.4 1.23E-10 20/234 K.EQQQQQQQQQQLAAQQLVFQQQLLQMQQLQQQQHLLSLQR.Q "sp|O15409|FOXP2_HUMAN,tr|Q0PRL4|Q0PRL4_HUMAN,tr|Q8N6B5|Q8N6B5_HUMAN,tr|A0A0U1RQR8|A0A0U1RQR8_HUMAN,tr|A0A0U1RQY3|A0A0U1RQY3_HUMAN" 5 4896.5165 12.25 108530 24920 4 4896.516778 1225.1364 Forkhead box protein P2 OS=Homo sapiens OX=9606 GN=FOXP2 PE=1 SV=2 6.85 3874 - 583042 - - - 0.0476 - 5.182 0.404 - 144.8 1 2 0 0.0002 40 0 0 0 1.48E+07 1.21E+06 - - - 3.2173 0.9471 221125_WJC_METTL3_EV_vs_WT_F07.24926.24926.4 3.71E-06 14/168 K.DIENQYETQITQIEHEVSSSGQEVQSSAK.E "sp|P35527|K1C9_HUMAN,tr|K7EQQ3|K7EQQ3_HUMAN" 2 3263.5066 2.34 108533 24926 4 3264.492189 816.8839 "Keratin, type I cytoskeletal 9 OS=Homo sapiens OX=9606 GN=KRT9 PE=1 SV=3" 4.14 3874.8 - 1.92E+06 - - - 302.0064 - 2.477 0.457 - 105.1 1 2 0 0.9856 29 0 0 0 3.05E+05 1.30E+05 - - - 3.2103 0.9311 221125_WJC_METTL3_EV_vs_WT_F07.24963.24963.3 0.000132 17/84 K.R[166.11]R[166.11]AEQDSTTVAAFASSLVSGLN.S "sp|Q86U44|MTA70_HUMAN,tr|F5H6D8|F5H6D8_HUMAN,tr|H0YFV6|H0YFV6_HUMAN,tr|B4DTN4|B4DTN4_HUMAN" 4 2299.1671 0 108546 24963 3 2299.167025 767.3963 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 6.07 3880.2 - 4.54E+06 - - - -0.0448 - 2.314 0.383 - 179.1 1 1 1 -0.0001 22 0 0 0 1.11E+05 1.16E+08 - - - 4.7991 1 221125_WJC_METTL3_EV_vs_WT_F07.24979.24979.4 9.81E-10 15/96 R.THNLEPYFESFINNLRR.R sp|P04264|K2C1_HUMAN 1 2149.0705 858.79 108553 24979 4 2149.068509 538.2749 "Keratin, type II cytoskeletal 1 OS=Homo sapiens OX=9606 GN=KRT1 PE=1 SV=6" 6.42 3882.4 - 459930 - - - -0.9204 - 3.121 0.546 - 210.1 1 2 0 -0.002 17 0 0 0 9.32E+07 1.08E+05 - - - 4.373 0.9999 221125_WJC_METTL3_EV_vs_WT_F07.25003.25003.4 9.74E-07 13/138 K.LREFASHLQQLQDALNELTEEHSK.A "sp|Q14980|NUMA1_HUMAN,tr|A0A087WY61|A0A087WY61_HUMAN,tr|F5H4J1|F5H4J1_HUMAN,tr|F5H6Y5|F5H6Y5_HUMAN" 4 2835.4151 0.41 108557 25003 4 2835.419703 709.8611 Nuclear mitotic apparatus protein 1 OS=Homo sapiens OX=9606 GN=NUMA1 PE=1 SV=2 4.92 3886.3 - 205932 - - - 1.6111 - 3.221 0.588 - 109.4 1 2 1 0.0046 24 0 0 0 3.42E+06 8.25E+06 - - - 4.7181 1 221125_WJC_METTL3_EV_vs_WT_F07.25007.25007.4 1.96E-10 21/222 K.GILGYTEHQVVSSDFNSDTHSSTFDAGAGIALNDHFVK.L "sp|P04406|G3P_HUMAN,tr|E7EUT5|E7EUT5_HUMAN" 2 4035.8875 0.71 108558 25007 4 4035.876195 1009.9792 Glyceraldehyde-3-phosphate dehydrogenase OS=Homo sapiens OX=9606 GN=GAPDH PE=1 SV=3 4.7 3886.9 - 449930 - - - -2.8021 - 3.125 0.66 - 99.3 1 2 0 -0.0113 38 0 0 0 9.01E+06 1.28E+07 - - - 5.2998 0.9682 221125_WJC_METTL3_EV_vs_WT_F07.25009.25009.3 1.93E-07 14/132 K.DHTPSQELALTQSVGGDSSADR[166.11]LFPPQWIC[160.03]C[160.03]DIR[166.11].Y sp|Q86U44|MTA70_HUMAN 1 3875.811 0.001 108559 25009 3 3876.800757 1292.9443 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 4.35 3887.2 - 394845 - - - 255.3646 - 2.384 0.516 - 58.5 1 2 1 0.9897 34 0 0 0 0.00E+00 5.20E+07 - - - 6.0175 0.9998 221125_WJC_METTL3_EV_vs_WT_F07.25025.25025.3 3.63E-07 14/112 K.MK[136.11]ETAENYLGHTAK[136.11]NAVITVPAYFNDSQR[166.11].Q "sp|P38646|GRP75_HUMAN,tr|H0Y8K0|H0Y8K0_HUMAN,tr|A0A7I2V2S7|A0A7I2V2S7_HUMAN,tr|A0A7I2V2G2|A0A7I2V2G2_HUMAN,tr|A0A7I2V3F7|A0A7I2V3F7_HUMAN,tr|A0A7I2YQB2|A0A7I2YQB2_HUMAN,tr|D6RCD7|D6RCD7_HUMAN" 7 3293.6349 0.001 108568 25025 3 3293.637947 1098.8856 "Stress-70 protein, mitochondrial OS=Homo sapiens OX=9606 GN=HSPA9 PE=1 SV=2" 6.51 3889.3 - 274417 - - - 0.9157 - 2.527 0.504 - 85.5 1 2 2 0.003 29 0 0 0 0.00E+00 2.00E+07 - - - 6.291 1 221125_WJC_METTL3_EV_vs_WT_F07.25034.25034.3 2.22E-08 13/92 K.GTAFVTLLNGEQAEAAINAFHQSR.L "sp|Q8IY67|RAVR1_HUMAN,tr|E9PAU2|E9PAU2_HUMAN,tr|A0A087WZ13|A0A087WZ13_HUMAN" 3 2544.2721 2.8 108572 25034 3 2544.264996 849.098 Ribonucleoprotein PTB-binding 1 OS=Homo sapiens OX=9606 GN=RAVER1 PE=1 SV=1 5.4 3890.6 - 193597 - - - -2.7922 - 2.907 0.589 - 156.9 1 2 0 -0.0071 24 0 0 0 2.11E+06 7.52E+05 - - - 7.5833 1 221125_WJC_METTL3_EV_vs_WT_F07.25044.25044.4 1.86E-11 27/276 R.TEGNIDDSLIGGNASAEGPEGEGTESTVITGVDIVMNHHLQETSFTK.E "sp|P13693|TCTP_HUMAN,tr|Q5W0H4|Q5W0H4_HUMAN,tr|A0A0B4J2C3|A0A0B4J2C3_HUMAN,tr|J3KPG2|J3KPG2_HUMAN,tr|E9PJF7|E9PJF7_HUMAN" 5 4856.257 1.85 108576 25044 4 4856.255933 1215.0715 Translationally-controlled tumor protein OS=Homo sapiens OX=9606 GN=TPT1 PE=1 SV=1 4.05 3892 - 128257 - - - -0.2292 - 6.354 0.734 - 275 1 2 0 -0.0011 47 0 0 0 1.73E+07 9.36E+06 - - - 6.1317 0.9998 221125_WJC_METTL3_EV_vs_WT_F07.25049.25049.4 0.00684 15/108 R.ADLEMQIESLKEELAYLKK.N sp|P02533|K1C14_HUMAN 1 2250.1817 999 108579 25049 4 2250.179625 563.5527 "Keratin, type I cytoskeletal 14 OS=Homo sapiens OX=9606 GN=KRT14 PE=1 SV=4" 4.59 3892.6 - 432353 - - - -0.9381 - 2.532 0.493 - 112.1 1 2 1 -0.0021 19 0 0 0 1.46E+07 0.00E+00 - - - 3.8308 0.9999 221125_WJC_METTL3_EV_vs_WT_F07.25057.25057.3 2.78E-07 12/100 R.SGPFGQIFRPDNFVFGQSGAGNNWAK.G "sp|P04350|TBB4A_HUMAN,sp|Q9BVA1|TBB2B_HUMAN,sp|P07437|TBB5_HUMAN,sp|Q13885|TBB2A_HUMAN,sp|P68371|TBB4B_HUMAN,tr|Q5ST81|Q5ST81_HUMAN,tr|Q5JP53|Q5JP53_HUMAN,tr|M0QY85|M0QY85_HUMAN,tr|M0QZL7|M0QZL7_HUMAN,tr|M0R278|M0R278_HUMAN,tr|M0R1I1|M0R1I1_HUMAN" 11 2797.3361 0.53 108582 25057 3 2797.32513 933.4526 Tubulin beta-4A chain OS=Homo sapiens OX=9606 GN=TUBB4A PE=1 SV=2 8.46 3893.6 - 164063 - - - -3.9205 - 2.374 0.627 - 73.7 1 2 0 -0.011 26 0 0 0 4.84E+06 9.16E+06 - - - 7.5165 0.9981 221125_WJC_METTL3_EV_vs_WT_F07.25066.25066.4 3.33E-12 26/264 S.SLVGQQFGAVGVAGSSLTSFGTETSNSGTLPQSSAVGSAFTQDTR[166.11].S "sp|Q8ND56|LS14A_HUMAN,tr|A0A140TA76|A0A140TA76_HUMAN,tr|K7EMZ9|K7EMZ9_HUMAN" 3 4401.1236 1.34 108586 25066 4 4401.118162 1101.2882 Protein LSM14 homolog A OS=Homo sapiens OX=9606 GN=LSM14A PE=1 SV=3 4.37 3894.8 - 1.35E+06 - - - -1.2358 - 4.647 0.583 - 214.1 1 1 0 -0.0054 45 0 0 0 1.78E+07 1.32E+07 - - - 4.7323 1 221125_WJC_METTL3_EV_vs_WT_F07.25072.25072.4 3.86E-11 27/264 S.SLVGQQFGAVGVAGSSLTSFGTETSNSGTLPQSSAVGSAFTQDTR.S "sp|Q8ND56|LS14A_HUMAN,tr|A0A140TA76|A0A140TA76_HUMAN,tr|K7EMZ9|K7EMZ9_HUMAN" 3 4391.1153 1.34 108587 25072 4 4391.112481 1098.7861 Protein LSM14 homolog A OS=Homo sapiens OX=9606 GN=LSM14A PE=1 SV=3 4.37 3895.8 - 701211 - - - -0.649 - 5.409 0.649 - 217.5 1 1 0 -0.0029 45 0 0 0 1.78E+07 1.32E+07 - - - 5.3503 1 221125_WJC_METTL3_EV_vs_WT_F07.25077.25077.3 9.11E-08 Dec-84 K.EKPYFPIPEEYTFIQNVPLEDR.V "sp|Q00839|HNRPU_HUMAN,tr|A0A1W2PQL0|A0A1W2PQL0_HUMAN,tr|A0A1W2PPL4|A0A1W2PPL4_HUMAN,tr|A0A1W2PQ74|A0A1W2PQ74_HUMAN,tr|Q5RI18|Q5RI18_HUMAN,tr|A0A1W2PP35|A0A1W2PP35_HUMAN,tr|A0A1W2PPS1|A0A1W2PPS1_HUMAN,tr|A0A1W2PRZ7|A0A1W2PRZ7_HUMAN,tr|A0A1W2PPH7|A0A1W2PPH7_HUMAN,tr|A0A1W2PP34|A0A1W2PP34_HUMAN,tr|A0A1X7SBS1|A0A1X7SBS1_HUMAN" 11 2723.3483 1.21 108590 25077 3 2723.346733 908.79 Heterogeneous nuclear ribonucleoprotein U OS=Homo sapiens OX=9606 GN=HNRNPU PE=1 SV=6 4.25 3896.5 - 360955 - - - -0.5695 - 2.493 0.578 - 106.2 1 2 0 -0.0016 22 0 0 0 4.48E+07 3.69E+07 - - - 7.1494 1 221125_WJC_METTL3_EV_vs_WT_F07.25080.25080.3 2.77E-08 13/84 K.EK[136.11]PYFPIPEEYTFIQNVPLEDR[166.11].V "sp|Q00839|HNRPU_HUMAN,tr|A0A1W2PQL0|A0A1W2PQL0_HUMAN,tr|A0A1W2PPL4|A0A1W2PPL4_HUMAN,tr|A0A1W2PQ74|A0A1W2PQ74_HUMAN,tr|Q5RI18|Q5RI18_HUMAN,tr|A0A1W2PP35|A0A1W2PP35_HUMAN,tr|A0A1W2PPS1|A0A1W2PPS1_HUMAN,tr|A0A1W2PRZ7|A0A1W2PRZ7_HUMAN,tr|A0A1W2PPH7|A0A1W2PPH7_HUMAN,tr|A0A1W2PP34|A0A1W2PP34_HUMAN,tr|A0A1X7SBS1|A0A1X7SBS1_HUMAN" 11 2741.3708 1.21 108592 25080 3 2741.373856 914.7975 Heterogeneous nuclear ribonucleoprotein U OS=Homo sapiens OX=9606 GN=HNRNPU PE=1 SV=6 4.25 3896.9 - 307076 - - - 1.1316 - 2.954 0.567 - 105.5 1 2 0 0.0031 22 0 0 0 4.48E+07 3.69E+07 - - - 7.4286 1 221125_WJC_METTL3_EV_vs_WT_F07.25107.25107.4 1.20E-16 21/222 K.GILGYTEHQVVSSDFNSDTHSSTFDAGAGIALNDHFVK[136.11].L "sp|P04406|G3P_HUMAN,tr|E7EUT5|E7EUT5_HUMAN" 2 4043.9017 1.02 108601 25107 4 4043.895534 1011.9827 Glyceraldehyde-3-phosphate dehydrogenase OS=Homo sapiens OX=9606 GN=GAPDH PE=1 SV=3 4.7 3900.7 - 507095 - - - -1.5258 - 4.111 0.764 - 158.3 1 2 0 -0.0062 38 0 0 0 2.89E+07 2.85E+07 - - - 6.2864 0.9976 221125_WJC_METTL3_EV_vs_WT_F07.25110.25110.4 0.000283 21/198 K.TIGTK[136.11]PVAHIDQFTADMLGSAELAEEVNLNGSGK[136.11].L sp|P50991|TCPD_HUMAN 1 3528.7741 0.6 108602 25110 4 3529.768015 883.2008 T-complex protein 1 subunit delta OS=Homo sapiens OX=9606 GN=CCT4 PE=1 SV=4 4.5 3901.2 - 481934 - - - 281.6562 - 3.142 0.541 - 135.6 1 2 0 0.9939 34 0 0 0 7.14E+06 1.19E+07 - - - 4.001 1 221125_WJC_METTL3_EV_vs_WT_F07.25115.25115.3 5.28E-08 24/112 K.DIENQYETQITQIEHEVSSSGQEVQSSAK.E "sp|P35527|K1C9_HUMAN,tr|K7EQQ3|K7EQQ3_HUMAN" 2 3263.5066 -1 108604 25115 3 3264.482675 1088.8428 "Keratin, type I cytoskeletal 9 OS=Homo sapiens OX=9606 GN=KRT9 PE=1 SV=3" 4.14 3901.8 - 4.08E+06 - - - 299.0912 - 4.657 0.611 - 711.1 1 2 0 0.9761 29 0 0 0 0.00E+00 0.00E+00 - - - 8.6209 0.8769 221125_WJC_METTL3_EV_vs_WT_F07.25117.25117.3 6.05E-08 14/92 K.R[166.11]R[166.11]AEQDSTTVAAFASSLVSGLNSS.A "sp|Q86U44|MTA70_HUMAN,tr|F5H6D8|F5H6D8_HUMAN,tr|H0YFV6|H0YFV6_HUMAN,tr|B4DTN4|B4DTN4_HUMAN" 4 2473.2312 0.02 108605 25117 3 2473.216992 825.4177 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 6.07 3902 - 302869 - - - -5.7382 - 3.353 0.61 - 224.8 1 1 1 -0.0142 24 0 0 0 1.20E+06 7.19E+07 - - - 8.147 0.9749 221125_WJC_METTL3_EV_vs_WT_F07.25134.25134.4 5.51E-07 14/120 N.VGTRPINLEPIFQGYIDSLKR.Y sp|P35908|K22E_HUMAN 1 2415.3274 230.62 108610 25134 4 2415.317437 604.8391 "Keratin, type II cytoskeletal 2 epidermal OS=Homo sapiens OX=9606 GN=KRT2 PE=1 SV=2" 8.56 3904.2 - 260937 - - - -4.1373 - 2.368 0.519 - 136.3 1 1 0 -0.01 21 0 0 0 5.86E+06 2.54E+04 - - - 4.0256 0.9492 221125_WJC_METTL3_EV_vs_WT_F07.25150.25150.4 4.18E-10 16/168 K.DIENQYETQITQIEHEVSSSGQEVQSSAK.E "sp|P35527|K1C9_HUMAN,tr|K7EQQ3|K7EQQ3_HUMAN" 2 3263.5066 -1 108613 25150 4 3264.478514 816.8839 "Keratin, type I cytoskeletal 9 OS=Homo sapiens OX=9606 GN=KRT9 PE=1 SV=3" 4.14 3906.6 - 1.96E+06 - - - 297.8162 - 3.76 0.614 - 145.1 1 2 0 0.9719 29 0 0 0 0.00E+00 0.00E+00 - - - 4.7092 0.9998 221125_WJC_METTL3_EV_vs_WT_F07.25188.25188.3 0.00243 Aug-72 R.YVASYLLAALGGNSSPSAK.D sp|P05387|RLA2_HUMAN 1 1867.968 1.74 108625 25188 3 1867.965515 623.6633 60S acidic ribosomal protein P2 OS=Homo sapiens OX=9606 GN=RPLP2 PE=1 SV=1 8.5 3912 - 221694 - - - -1.3191 - 1.89 0.422 - 58.4 1 2 0 -0.0025 19 0 0 0 4.45E+06 2.56E+06 - - - 4.8081 0.9999 221125_WJC_METTL3_EV_vs_WT_F07.25189.25189.3 0.000139 Sep-72 R.YVASYLLAALGGNSSPSAK[136.11].D sp|P05387|RLA2_HUMAN 1 1875.9822 1.74 108626 25189 3 1875.981692 626.3347 60S acidic ribosomal protein P2 OS=Homo sapiens OX=9606 GN=RPLP2 PE=1 SV=1 8.5 3912.1 - 167051 - - - -0.2596 - 1.776 0.477 - 73.4 1 2 0 -0.0005 19 0 0 0 4.45E+06 2.56E+06 - - - 5.269 0.9904 221125_WJC_METTL3_EV_vs_WT_F07.25194.25194.4 0.00219 14/126 M.NVGTRPINLEPIFQGYIDSLKR.Y sp|P35908|K22E_HUMAN 1 2529.3704 999 108628 25194 4 2529.373406 633.3499 "Keratin, type II cytoskeletal 2 epidermal OS=Homo sapiens OX=9606 GN=KRT2 PE=1 SV=2" 8.59 3912.8 - 595010 - - - 1.2054 - 2.673 0.434 - 92.5 1 1 0 0.003 22 0 0 0 1.84E+07 0.00E+00 - - - 3.3244 1 221125_WJC_METTL3_EV_vs_WT_F07.25197.25197.4 1.38E-05 12/252 K.DQLGKNEEGAPQEGILEDMPVDPDNEAYEMPSEEGYQDYEPEA.- sp|P37840|SYUA_HUMAN 1 4827.0124 2.67 108629 25197 4 4827.00873 1207.7604 Alpha-synuclein OS=Homo sapiens OX=9606 GN=SNCA PE=1 SV=1 3.36 3913.2 - 526469 - - - -0.7535 - 2.369 0.671 - 29.8 1 2 1 -0.0036 43 0 0 0 4.60E+06 1.73E+06 - - - 5.3108 1 221125_WJC_METTL3_EV_vs_WT_F07.25209.25209.4 1.75E-08 13/168 R.R[166.11]AEQDSTTVAAFASSLVSGLNSSASEPAK[136.11].E "sp|Q86U44|MTA70_HUMAN,tr|F5H6D8|F5H6D8_HUMAN,tr|H0YFV6|H0YFV6_HUMAN,tr|B4DTN4|B4DTN4_HUMAN" 4 2898.4326 0.01 108637 25209 4 2898.434795 725.6154 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 4.68 3914.8 - 233560 - - - 0.7642 - 2.961 0.626 - 78.7 1 2 0 0.0022 29 0 0 0 6.75E+06 1.13E+09 - - - 5.0086 0.9999 221125_WJC_METTL3_EV_vs_WT_F07.25210.25210.4 0.000331 10/108 R.GLLQDDAHPTLVTYADHSK[136.11].L "sp|Q86U44|MTA70_HUMAN,tr|F5H6D8|F5H6D8_HUMAN,tr|H0YFV6|H0YFV6_HUMAN,tr|B4DTN4|B4DTN4_HUMAN" 4 2088.0367 0.02 108638 25210 4 2088.037126 523.0165 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 5.13 3914.9 - 216492 - - - 0.1882 - 1.904 0.472 - 27.1 1 2 0 0.0004 19 0 0 0 1.11E+05 5.59E+06 - - - 3.552 1 221125_WJC_METTL3_EV_vs_WT_F07.25211.25211.3 1.91E-13 24/112 R.R[166.11]AEQDSTTVAAFASSLVSGLNSSASEPAK[136.11].E "sp|Q86U44|MTA70_HUMAN,tr|F5H6D8|F5H6D8_HUMAN,tr|H0YFV6|H0YFV6_HUMAN,tr|B4DTN4|B4DTN4_HUMAN" 4 2898.4326 0.01 108639 25211 3 2898.434981 967.1515 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 4.68 3915 - 1.50E+06 - - - 0.8284 - 5.17 0.688 - 460.1 1 2 0 0.0024 29 0 0 0 5.88E+07 6.99E+09 - - - 9.9895 1 221125_WJC_METTL3_EV_vs_WT_F07.25213.25213.3 5.90E-07 Aug-68 K.YVHYEIDAC[160.03]MDSEAPGSK[136.11].D "sp|Q86U44|MTA70_HUMAN,tr|H0YFV6|H0YFV6_HUMAN" 2 2078.8805 0.07 108641 25213 3 2078.877883 693.9674 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 4.31 3915.3 - 99410.4 - - - -1.255 - 1.794 0.638 - 61 1 2 0 -0.0026 18 0 0 0 1.45E+05 1.94E+06 - - - 7.1077 0.8695 221125_WJC_METTL3_EV_vs_WT_F07.25218.25218.4 3.46E-05 17/198 K.QSKPVTTPEEIAQVATISANGDKEIGNIISDAMK.K "sp|P10809|CH60_HUMAN,tr|A0A7I2V599|A0A7I2V599_HUMAN,tr|E7EXB4|E7EXB4_HUMAN,tr|A0A7I2YQ71|A0A7I2YQ71_HUMAN,tr|E7ESH4|E7ESH4_HUMAN,tr|A0A7I2V5M1|A0A7I2V5M1_HUMAN,tr|A0A7I2V5K3|A0A7I2V5K3_HUMAN,tr|A0A7I2V369|A0A7I2V369_HUMAN" 8 3554.8138 26.22 108643 25218 4 3555.796972 889.7107 "60 kDa heat shock protein, mitochondrial OS=Homo sapiens OX=9606 GN=HSPD1 PE=1 SV=2" 4.51 3915.9 - 431758 - - - 276.5768 - 2.95 0.493 - 117.7 1 2 1 0.9832 34 0 0 0 7.18E+06 2.74E+05 - - - 3.5673 1 221125_WJC_METTL3_EV_vs_WT_F07.25233.25233.2 2.70E-17 28/62 R.AEQDSTTVAAFASSLVSGLNSSASEPAK[136.11]EPAK[136.11].K "sp|Q86U44|MTA70_HUMAN,tr|F5H6D8|F5H6D8_HUMAN,tr|H0YFV6|H0YFV6_HUMAN,tr|B4DTN4|B4DTN4_HUMAN" 4 3165.5648 0.001 108648 25233 2 3166.560187 1583.7897 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 4.41 3918.1 - 594873 - - - 314.432 - 4.972 0.623 - 1354.7 1 2 1 0.9954 32 0 0 0 0.00E+00 2.02E+08 - - - 7.273 0.9999 221125_WJC_METTL3_EV_vs_WT_F07.25244.25244.4 1.13E-07 10/162 R.AETEC[160.03]QNTEYQQLLDIKIRLENEIQTYR.S "sp|P13645|K1C10_HUMAN,tr|A0A1B0GVI3|A0A1B0GVI3_HUMAN" 2 3497.7097 3.38 108651 25244 4 3497.712564 875.4347 "Keratin, type I cytoskeletal 10 OS=Homo sapiens OX=9606 GN=KRT10 PE=1 SV=6" 4.42 3919.6 - 536895 - - - 0.8294 - 2.382 0.559 - 48.5 1 2 2 0.0029 28 0 0 0 7.69E+06 2.27E+06 - - - 4.3602 0.9779 221125_WJC_METTL3_EV_vs_WT_F07.25270.25270.3 2.18E-08 24/96 K.R[166.11]R[166.11]AEQDSTTVAAFASSLVSGLNSSA.S "sp|Q86U44|MTA70_HUMAN,tr|F5H6D8|F5H6D8_HUMAN,tr|H0YFV6|H0YFV6_HUMAN,tr|B4DTN4|B4DTN4_HUMAN" 4 2544.2683 0.01 108655 25270 3 2544.260521 849.0967 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 6.07 3923.6 - 8.76E+06 - - - -3.0567 - 4.158 0.547 - 556.6 1 1 1 -0.0078 25 0 0 0 4.25E+06 7.48E+08 - - - 7.9148 1 221125_WJC_METTL3_EV_vs_WT_F07.25273.25273.2 1.99E-11 22/32 L.VSGLNSSASEPAK[136.11]EPAK[136.11].K "sp|Q86U44|MTA70_HUMAN,tr|F5H6D8|F5H6D8_HUMAN,tr|H0YFV6|H0YFV6_HUMAN,tr|B4DTN4|B4DTN4_HUMAN" 4 1686.8759 0.33 108656 25273 2 1686.865615 844.4452 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 6.11 3924 - 672921 - - - -6.1143 - 3.857 0.667 - 1411.4 1 1 1 -0.0103 17 0 0 0 2.90E+06 8.69E+06 - - - 7.283 0.9987 221125_WJC_METTL3_EV_vs_WT_F07.25275.25275.3 0.00367 Dec-60 R.QNLEPLFEQYINNLRR.Q "sp|P48668|K2C6C_HUMAN,sp|P04259|K2C6B_HUMAN,sp|P13647|K2C5_HUMAN,sp|P02538|K2C6A_HUMAN,tr|F8W0C6|F8W0C6_HUMAN" 5 2046.0647 320.84 108657 25275 3 2046.060983 683.0288 "Keratin, type II cytoskeletal 6C OS=Homo sapiens OX=9606 GN=KRT6C PE=1 SV=3" 6.14 3924.2 - 786936 - - - -1.8035 - 2.096 0.27 - 117.6 1 2 0 -0.0037 16 0 0 0 2.66E+07 8.29E+04 - - - 3.448 1 221125_WJC_METTL3_EV_vs_WT_F07.25306.25306.4 4.10E-12 41/222 K.GILGYTEHQVVSSDFNSDTHSSTFDAGAGIALNDHFVK.L "sp|P04406|G3P_HUMAN,tr|E7EUT5|E7EUT5_HUMAN" 2 4035.8875 0.96 108668 25306 4 4035.885576 1009.9792 Glyceraldehyde-3-phosphate dehydrogenase OS=Homo sapiens OX=9606 GN=GAPDH PE=1 SV=3 4.7 3928.4 - 1.42E+06 - - - -0.4777 - 5.904 0.743 - 758.6 1 2 0 -0.0019 38 0 0 0 1.47E+08 1.53E+08 - - - 6.2103 1 221125_WJC_METTL3_EV_vs_WT_F07.25309.25309.4 2.76E-15 21/258 R.FGGFGGPGGVGGLGGPGGFGPGGYPGGIHEVSVNQSLLQPLNVK.V sp|P35908|K22E_HUMAN 1 4091.0653 999 108671 25309 4 4091.069281 1023.7736 "Keratin, type II cytoskeletal 2 epidermal OS=Homo sapiens OX=9606 GN=KRT2 PE=1 SV=2" 6.75 3928.7 - 715971 - - - 0.9611 - 4.218 0.637 - 98.4 1 2 0 0.0039 44 0 0 0 8.31E+06 0.00E+00 - - - 5.1772 0.8642 221125_WJC_METTL3_EV_vs_WT_F07.25316.25316.3 0.000916 Sep-84 M.ADPPWDIHMELPYGTLTDDEMR[166.11].R sp|Q86U44|MTA70_HUMAN 1 2611.1598 0.33 108674 25316 3 2611.153177 871.3939 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 3.96 3929.7 - 192798 - - - -2.5537 - 1.702 0.354 - 69.5 1 1 0 -0.0067 22 0 0 0 9.17E+05 2.80E+06 - - - 3.7457 0.996 221125_WJC_METTL3_EV_vs_WT_F07.25318.25318.4 2.39E-05 26/186 R.AEQDSTTVAAFASSLVSGLNSSASEPAK[136.11]EPAK[136.11].K "sp|Q86U44|MTA70_HUMAN,tr|F5H6D8|F5H6D8_HUMAN,tr|H0YFV6|H0YFV6_HUMAN,tr|B4DTN4|B4DTN4_HUMAN" 4 3165.5648 0.01 108675 25318 4 3166.561225 792.3985 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 4.41 3929.9 - 1.54E+06 - - - 314.7599 - 5.129 0.583 - 310.3 1 2 1 0.9964 32 0 0 0 7.10E+07 5.19E+09 - - - 4.5181 0.9999 221125_WJC_METTL3_EV_vs_WT_F07.25319.25319.2 5.85E-07 22-Oct K.VDLLNQEIEFLK.V sp|P35908|K22E_HUMAN 1 1459.7922 999 108676 25319 2 1459.790638 730.9034 "Keratin, type II cytoskeletal 2 epidermal OS=Homo sapiens OX=9606 GN=KRT2 PE=1 SV=2" 4.14 3930 - 348781 - - - -1.1015 - 2.323 0.521 - 474.7 1 2 0 -0.0016 12 0 0 0 8.58E+06 0.00E+00 - - - 5.1063 1 221125_WJC_METTL3_EV_vs_WT_F07.25324.25324.3 1.06E-06 14/60 R.NVQALEIELQSQLALK.Q "sp|P13645|K1C10_HUMAN,tr|A0A1B0GVI3|A0A1B0GVI3_HUMAN" 2 1796.0044 7.13 108678 25324 3 1796.003588 599.6754 "Keratin, type I cytoskeletal 10 OS=Homo sapiens OX=9606 GN=KRT10 PE=1 SV=6" 4.53 3930.8 - 339375 - - - -0.4321 - 2.744 0.561 - 300.3 1 2 0 -0.0008 16 0 0 0 4.60E+06 6.45E+05 - - - 7.3844 1 221125_WJC_METTL3_EV_vs_WT_F07.25341.25341.4 5.57E-14 41/204 K.QSKPVTTPEEIAQVATISANGDKEIGNIISDAMKK.V "sp|P10809|CH60_HUMAN,tr|A0A7I2V599|A0A7I2V599_HUMAN,tr|E7EXB4|E7EXB4_HUMAN,tr|A0A7I2YQ71|A0A7I2YQ71_HUMAN,tr|E7ESH4|E7ESH4_HUMAN,tr|A0A7I2V5M1|A0A7I2V5M1_HUMAN,tr|A0A7I2V5K3|A0A7I2V5K3_HUMAN,tr|A0A7I2V369|A0A7I2V369_HUMAN" 8 3682.9088 1.24 108687 25341 4 3682.913874 921.7345 "60 kDa heat shock protein, mitochondrial OS=Homo sapiens OX=9606 GN=HSPD1 PE=1 SV=2" 4.94 3933 - 1.38E+06 - - - 1.3897 - 6.509 0.646 - 925.6 1 2 1 0.0051 35 0 0 0 1.36E+08 1.10E+08 - - - 5.4027 0.9929 221125_WJC_METTL3_EV_vs_WT_F07.25349.25349.4 8.67E-08 13/150 Q.KNYSPYYNTIDDLKDQIVDLTVGNNK.T sp|P35527|K1C9_HUMAN 1 3029.4982 20.23 108691 25349 4 3029.50219 758.3818 "Keratin, type I cytoskeletal 9 OS=Homo sapiens OX=9606 GN=KRT9 PE=1 SV=3" 4.58 3934.1 - 533042 - - - 1.3184 - 3.404 0.602 - 78.2 1 1 1 0.004 26 0 0 0 1.20E+07 5.93E+05 - - - 4.8511 1 221125_WJC_METTL3_EV_vs_WT_F07.25356.25356.4 2.80E-20 41/222 K.GILGYTEHQVVSSDFNSDTHSSTFDAGAGIALNDHFVK[136.11].L "sp|P04406|G3P_HUMAN,tr|E7EUT5|E7EUT5_HUMAN" 2 4043.9017 0.97 108695 25356 4 4043.902584 1011.9827 Glyceraldehyde-3-phosphate dehydrogenase OS=Homo sapiens OX=9606 GN=GAPDH PE=1 SV=3 4.7 3935 - 2.73E+06 - - - 0.2176 - 5.869 0.788 - 686.3 1 2 0 0.0009 38 0 0 0 1.48E+08 1.53E+08 - - - 6.6006 0.9291 221125_WJC_METTL3_EV_vs_WT_F07.25358.25358.3 9.88E-11 17/108 R.PHNVQPNWITLGNQLDGIHLLDPDVVAR[166.11].F sp|Q86U44|MTA70_HUMAN 1 3140.6395 0.001 108697 25358 3 3141.635333 1047.8871 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 5.14 3935.2 - 410776 - - - 317.0841 - 3.189 0.651 - 151.9 1 1 0 0.9958 28 0 0 0 0.00E+00 1.87E+07 - - - 8.1902 1 221125_WJC_METTL3_EV_vs_WT_F07.25377.25377.3 1.28E-13 32/124 R.AEQDSTTVAAFASSLVSGLNSSASEPAK[136.11]EPAK[136.11].K "sp|Q86U44|MTA70_HUMAN,tr|F5H6D8|F5H6D8_HUMAN,tr|H0YFV6|H0YFV6_HUMAN,tr|B4DTN4|B4DTN4_HUMAN" 4 3165.5648 0.03 108704 25377 3 3166.557868 1056.1956 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 4.41 3937.8 - 1.71E+06 - - - 313.6995 - 4.77 0.62 - 863.6 1 2 1 0.993 32 0 0 0 1.53E+06 4.40E+07 - - - 8.7717 1 221125_WJC_METTL3_EV_vs_WT_F07.25385.25385.4 4.48E-09 21/144 R.RKLEGDSTDLSDQIAELQAQIAELK.M sp|P35579|MYH9_HUMAN 1 2770.4349 1.02 108708 25385 4 2770.435263 693.616 Myosin-9 OS=Homo sapiens OX=9606 GN=MYH9 PE=1 SV=4 4.3 3938.9 - 424236 - - - 0.1426 - 4.131 0.68 - 293.4 1 2 1 0.0004 25 0 0 0 6.12E+07 5.97E+07 - - - 5.5959 1 221125_WJC_METTL3_EV_vs_WT_F07.25394.25394.3 1.55E-17 28/96 R.RKLEGDSTDLSDQIAELQAQIAELK.M sp|P35579|MYH9_HUMAN 1 2770.4349 1.12 108714 25394 3 2770.435741 924.4856 Myosin-9 OS=Homo sapiens OX=9606 GN=MYH9 PE=1 SV=4 4.3 3940.1 - 404254 - - - 0.3151 - 5.352 0.726 - 935.7 1 2 1 0.0009 25 0 0 0 1.84E+07 1.63E+07 - - - 10.4932 1 221125_WJC_METTL3_EV_vs_WT_F07.25399.25399.4 1.45E-13 36/144 R.R[166.11]K[136.11]LEGDSTDLSDQIAELQAQIAELK[136.11].M sp|P35579|MYH9_HUMAN 1 2796.4715 1.02 108718 25399 4 2796.476728 700.1252 Myosin-9 OS=Homo sapiens OX=9606 GN=MYH9 PE=1 SV=4 4.3 3940.8 - 3.31E+06 - - - 1.8559 - 5.361 0.681 - 974.2 1 2 1 0.0052 25 0 0 0 6.12E+07 5.97E+07 - - - 5.6862 1 221125_WJC_METTL3_EV_vs_WT_F07.25402.25402.4 7.69E-09 22/102 R.SPSELFAQHIVTIVHHVK.E "sp|Q9Y2W1|TR150_HUMAN,tr|A0A3B3ITZ9|A0A3B3ITZ9_HUMAN" 2 2041.1109 2.66 108720 25402 4 2041.115641 511.285 Thyroid hormone receptor-associated protein 3 OS=Homo sapiens OX=9606 GN=THRAP3 PE=1 SV=2 6.78 3941.1 - 648409 - - - 2.3252 - 3.516 0.572 - 354.3 1 2 0 0.0047 18 0 0 0 1.58E+07 5.93E+06 - - - 4.6341 1 221125_WJC_METTL3_EV_vs_WT_F07.25403.25403.4 8.14E-09 17/102 R.SPSELFAQHIVTIVHHVK[136.11].E "sp|Q9Y2W1|TR150_HUMAN,tr|A0A3B3ITZ9|A0A3B3ITZ9_HUMAN" 2 2049.1251 2.66 108721 25403 4 2049.126189 513.2886 Thyroid hormone receptor-associated protein 3 OS=Homo sapiens OX=9606 GN=THRAP3 PE=1 SV=2 6.78 3941.2 - 286730 - - - 0.5339 - 3.131 0.624 - 226 1 2 0 0.0011 18 0 0 0 1.58E+07 5.93E+06 - - - 5.048 1 221125_WJC_METTL3_EV_vs_WT_F07.25406.25406.3 3.21E-14 29/96 R.R[166.11]K[136.11]LEGDSTDLSDQIAELQAQIAELK[136.11].M sp|P35579|MYH9_HUMAN 1 2796.4715 1.12 108722 25406 3 2796.476057 933.1645 Myosin-9 OS=Homo sapiens OX=9606 GN=MYH9 PE=1 SV=4 4.3 3941.6 - 1.31E+06 - - - 1.616 - 5.195 0.704 - 1102.8 1 2 1 0.0045 25 0 0 0 1.84E+07 1.63E+07 - - - 10.1784 1 221125_WJC_METTL3_EV_vs_WT_F07.25407.25407.3 4.13E-12 18/68 K.GHYTEGAELVDSVLDVVR[166.11].K "sp|Q9BVA1|TBB2B_HUMAN,sp|P07437|TBB5_HUMAN,sp|Q13509|TBB3_HUMAN,sp|Q13885|TBB2A_HUMAN,sp|P68371|TBB4B_HUMAN,tr|A0A0B4J269|A0A0B4J269_HUMAN,tr|Q5ST81|Q5ST81_HUMAN,tr|Q5JP53|Q5JP53_HUMAN,tr|G3V2A3|G3V2A3_HUMAN" 9 1967.9828 0.83 108723 25407 3 1967.987015 657.0015 Tubulin beta-2B chain OS=Homo sapiens OX=9606 GN=TUBB2B PE=1 SV=1 4.31 3941.8 - 361283 - - - 2.1464 - 3.19 0.675 - 500.7 1 2 0 0.0042 18 0 0 0 2.96E+06 3.55E+06 - - - 8.953 0.9999 221125_WJC_METTL3_EV_vs_WT_F07.25409.25409.4 0.0126 9/150 K.EVLAGR[166.11]PLFPHVLC[160.03]HNC[160.03]AVEFNFGQK[136.11].E "sp|Q00839|HNRPU_HUMAN,tr|A0A1W2PQL0|A0A1W2PQL0_HUMAN,tr|A0A1W2PPL4|A0A1W2PPL4_HUMAN,tr|A0A1W2PQ74|A0A1W2PQ74_HUMAN,tr|Q5RI18|Q5RI18_HUMAN,tr|A0A1W2PP35|A0A1W2PP35_HUMAN,tr|A0A1W2PPS1|A0A1W2PPS1_HUMAN,tr|A0A1W2PRZ7|A0A1W2PRZ7_HUMAN,tr|A0A1W2PPH7|A0A1W2PPH7_HUMAN,tr|A0A1W2PP34|A0A1W2PP34_HUMAN,tr|A0A1X7SBS1|A0A1X7SBS1_HUMAN" 11 3056.5232 0.95 108725 25409 4 3056.525615 765.1381 Heterogeneous nuclear ribonucleoprotein U OS=Homo sapiens OX=9606 GN=HNRNPU PE=1 SV=6 6.99 3942 - 471508 - - - 0.7878 - 2.439 0.416 - 42.4 1 2 0 0.0024 26 0 0 0 2.34E+06 2.46E+06 - - - 3.1274 1 221125_WJC_METTL3_EV_vs_WT_F07.25413.25413.3 7.98E-10 15/68 K.GHYTEGAELVDSVLDVVR.K "sp|Q9BVA1|TBB2B_HUMAN,sp|P07437|TBB5_HUMAN,sp|Q13509|TBB3_HUMAN,sp|Q13885|TBB2A_HUMAN,sp|P68371|TBB4B_HUMAN,tr|A0A0B4J269|A0A0B4J269_HUMAN,tr|Q5ST81|Q5ST81_HUMAN,tr|Q5JP53|Q5JP53_HUMAN,tr|G3V2A3|G3V2A3_HUMAN" 9 1957.9745 0.81 108727 25413 3 1957.975465 653.6655 Tubulin beta-2B chain OS=Homo sapiens OX=9606 GN=TUBB2B PE=1 SV=1 4.31 3942.6 - 244729 - - - 0.4821 - 2.84 0.614 - 333.4 1 2 0 0.0009 18 0 0 0 2.86E+06 3.55E+06 - - - 7.9844 0.9981 221125_WJC_METTL3_EV_vs_WT_F07.25418.25418.4 2.56E-11 27/162 R.PHNVQPNWITLGNQLDGIHLLDPDVVAR[166.11].F sp|Q86U44|MTA70_HUMAN 1 3140.6395 0.02 108729 25418 4 3140.636732 786.1671 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 5.14 3943.3 - 872971 - - - -0.8769 - 4.559 0.577 - 339.1 1 1 0 -0.0028 28 0 0 0 5.01E+06 2.36E+08 - - - 4.7185 1 221125_WJC_METTL3_EV_vs_WT_F07.25439.25439.2 2.20E-12 22/32 L.GNQLDGIHLLDPDVVAR[166.11].F sp|Q86U44|MTA70_HUMAN 1 1840.9671 0.001 108735 25439 2 1840.96466 921.4908 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 4.41 3946.4 - 1.50E+06 - - - -1.3151 - 3.796 0.701 - 857.1 1 1 0 -0.0024 17 0 0 0 0.00E+00 4.24E+07 - - - 7.4974 1 221125_WJC_METTL3_EV_vs_WT_F07.25451.25451.2 3.65E-06 16/24 L.DGIHLLDPDVVAR[166.11].F sp|Q86U44|MTA70_HUMAN 1 1428.76 0.09 108740 25451 2 1428.75653 715.3873 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 4.41 3947.9 - 1.05E+06 - - - -2.4623 - 2.913 0.548 - 792.5 1 1 0 -0.0035 13 0 0 0 5.39E+06 5.91E+07 - - - 5.8315 0.9999 221125_WJC_METTL3_EV_vs_WT_F07.25459.25459.4 7.09E-07 24/150 R.SFGTEDRPTDRPIPPRDEVFEYIIFR.G "sp|Q8ND56|LS14A_HUMAN,tr|I3L4Q1|I3L4Q1_HUMAN,tr|A0A140TA76|A0A140TA76_HUMAN,tr|K7EMZ9|K7EMZ9_HUMAN" 4 3151.5727 1.39 108743 25459 4 3151.566271 788.9005 Protein LSM14 homolog A OS=Homo sapiens OX=9606 GN=LSM14A PE=1 SV=3 4.59 3948.9 - 4.90E+06 - - - -2.0396 - 2.961 0.548 - 84.9 1 2 1 -0.0064 26 0 0 0 4.47E+07 3.21E+07 - - - 4.3364 0.9934 221125_WJC_METTL3_EV_vs_WT_F07.25477.25477.4 2.31E-11 29/174 F.GR[166.11]PHNVQPNWITLGNQLDGIHLLDPDVVAR[166.11].F sp|Q86U44|MTA70_HUMAN 1 3363.7703 0.07 108747 25477 4 3363.759605 841.9499 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 5.99 3951.6 - 8.49E+06 - - - -3.1887 - 4.449 0.577 - 313.9 1 1 0 -0.0107 30 0 0 0 3.56E+06 5.20E+07 - - - 4.702 1 221125_WJC_METTL3_EV_vs_WT_F07.25497.25497.4 4.81E-11 20/102 K.STSESFIQHIVSLVHHVK.E "sp|Q9NYF8|BCLF1_HUMAN,tr|E9PKI6|E9PKI6_HUMAN,tr|A0A1W2PQ43|A0A1W2PQ43_HUMAN,tr|E9PK91|E9PK91_HUMAN,tr|E9PJA7|E9PJA7_HUMAN,tr|E9PK09|E9PK09_HUMAN,tr|E9PQN2|E9PQN2_HUMAN" 7 2047.0851 2.03 108749 25497 4 2047.084603 512.7785 Bcl-2-associated transcription factor 1 OS=Homo sapiens OX=9606 GN=BCLAF1 PE=1 SV=2 6.78 3954.8 - 2.98E+06 - - - -0.2301 - 3.63 0.5 - 253 1 2 0 -0.0005 18 0 0 0 7.15E+07 3.52E+07 - - - 4.0195 1 221125_WJC_METTL3_EV_vs_WT_F07.25499.25499.4 6.53E-12 22/102 K.STSESFIQHIVSLVHHVK[136.11].E "sp|Q9NYF8|BCLF1_HUMAN,tr|E9PKI6|E9PKI6_HUMAN,tr|A0A1W2PQ43|A0A1W2PQ43_HUMAN,tr|E9PK91|E9PK91_HUMAN,tr|E9PJA7|E9PJA7_HUMAN,tr|E9PK09|E9PK09_HUMAN,tr|E9PQN2|E9PQN2_HUMAN" 7 2055.0993 2.03 108750 25499 4 2055.091631 514.7821 Bcl-2-associated transcription factor 1 OS=Homo sapiens OX=9606 GN=BCLAF1 PE=1 SV=2 6.78 3955 - 2.42E+06 - - - -3.719 - 3.876 0.618 - 367.4 1 2 0 -0.0076 18 0 0 0 7.15E+07 3.52E+07 - - - 5.0671 1 221125_WJC_METTL3_EV_vs_WT_F07.25505.25505.3 1.83E-09 17/68 K.STSESFIQHIVSLVHHVK.E "sp|Q9NYF8|BCLF1_HUMAN,tr|E9PKI6|E9PKI6_HUMAN,tr|A0A1W2PQ43|A0A1W2PQ43_HUMAN,tr|E9PK91|E9PK91_HUMAN,tr|E9PJA7|E9PJA7_HUMAN,tr|E9PK09|E9PK09_HUMAN,tr|E9PQN2|E9PQN2_HUMAN" 7 2047.0851 0.47 108752 25505 3 2047.086332 683.369 Bcl-2-associated transcription factor 1 OS=Homo sapiens OX=9606 GN=BCLAF1 PE=1 SV=2 6.78 3955.8 - 2.51E+06 - - - 0.6145 - 3.261 0.583 - 403 1 2 0 0.0013 18 0 0 0 2.20E+07 4.73E+07 - - - 7.9829 1 221125_WJC_METTL3_EV_vs_WT_F07.25514.25514.4 3.48E-15 41/162 R.HVDAHATLSDGVVVQVMGLLSNSGQPER.K "sp|Q9UN86|G3BP2_HUMAN,tr|A0A7I2V3E2|A0A7I2V3E2_HUMAN,tr|D6RAC7|D6RAC7_HUMAN,tr|D6RB17|D6RB17_HUMAN,tr|A0A7I2YQS2|A0A7I2YQS2_HUMAN,tr|A0A7I2YQG8|A0A7I2YQG8_HUMAN,tr|A0A7I2V572|A0A7I2V572_HUMAN,tr|D6RBW8|D6RBW8_HUMAN" 8 2915.456 1.23 108755 25514 4 2915.462485 729.8713 Ras GTPase-activating protein-binding protein 2 OS=Homo sapiens OX=9606 GN=G3BP2 PE=1 SV=2 5.21 3957 - 753706 - - - 2.2401 - 5.357 0.634 - 1300.5 1 2 0 0.0065 28 0 0 0 2.30E+07 1.87E+07 - - - 5.2636 0.9921 221125_WJC_METTL3_EV_vs_WT_F07.25517.25517.4 7.88E-05 21/168 R.K[136.11]IELFGR[166.11]PHNVQPNWITLGNQLDGIHLLD.P sp|Q86U44|MTA70_HUMAN 1 3354.7956 1.56 108756 25517 4 3354.796108 839.7062 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 6.02 3957.4 - 880136 - - - 0.1514 - 3.444 0.442 - 198.5 1 1 0 0.0005 29 0 0 0 1.10E+07 7.04E+06 - - - 3.4541 1 221125_WJC_METTL3_EV_vs_WT_F07.25523.25523.4 9.92E-14 39/162 R.HVDAHATLSDGVVVQVMGLLSNSGQPER[166.11].K "sp|Q9UN86|G3BP2_HUMAN,tr|A0A7I2V3E2|A0A7I2V3E2_HUMAN,tr|D6RAC7|D6RAC7_HUMAN,tr|D6RB17|D6RB17_HUMAN,tr|A0A7I2YQS2|A0A7I2YQS2_HUMAN,tr|A0A7I2YQG8|A0A7I2YQG8_HUMAN,tr|A0A7I2V572|A0A7I2V572_HUMAN,tr|D6RBW8|D6RBW8_HUMAN" 8 2925.4642 1.23 108759 25523 4 2925.470745 732.3733 Ras GTPase-activating protein-binding protein 2 OS=Homo sapiens OX=9606 GN=G3BP2 PE=1 SV=2 5.21 3958.1 - 1.37E+06 - - - 2.229 - 5.183 0.626 - 1087.7 1 2 0 0.0065 28 0 0 0 2.30E+07 1.87E+07 - - - 5.1838 0.9984 221125_WJC_METTL3_EV_vs_WT_F07.25525.25525.4 1.73E-05 28/198 K.TIGTK[136.11]PVAHIDQFTADMLGSAELAEEVNLNGSGK[136.11].L sp|P50991|TCPD_HUMAN 1 3528.7741 0.17 108761 25525 4 3529.769956 883.2008 T-complex protein 1 subunit delta OS=Homo sapiens OX=9606 GN=CCT4 PE=1 SV=4 4.5 3958.4 - 643432 - - - 282.2062 - 3.406 0.542 - 296.8 1 2 0 0.9958 34 0 0 0 7.82E+05 4.50E+06 - - - 4.0332 1 221125_WJC_METTL3_EV_vs_WT_F07.25528.25528.3 8.21E-15 23/60 R.THNLEPYFESFINNLR.R sp|P04264|K2C1_HUMAN 1 1992.9694 187.12 108762 25528 3 1992.975394 665.3304 "Keratin, type II cytoskeletal 1 OS=Homo sapiens OX=9606 GN=KRT1 PE=1 SV=6" 5.37 3958.8 - 2.87E+06 - - - 3.0196 - 4.252 0.697 - 1079.8 1 2 0 0.006 16 0 0 0 5.75E+07 3.07E+05 - - - 10.023 0.9997 221125_WJC_METTL3_EV_vs_WT_F07.25532.25532.4 0.000513 9/108 R.GLLQDDAHPTLVTYADHSK[136.11].L "sp|Q86U44|MTA70_HUMAN,tr|F5H6D8|F5H6D8_HUMAN,tr|H0YFV6|H0YFV6_HUMAN,tr|B4DTN4|B4DTN4_HUMAN" 4 2088.0367 0.001 108765 25532 4 2088.04254 523.0165 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 5.13 3959.3 - 192191 - - - 2.7811 - 1.838 0.431 - 27 1 2 0 0.0058 19 0 0 0 0.00E+00 6.17E+06 - - - 3.1817 0.9939 221125_WJC_METTL3_EV_vs_WT_F07.25538.25538.4 0.0195 Jun-96 R.THNLEPYFESFINNLRR.R sp|P04264|K2C1_HUMAN 1 2149.0705 999 108769 25538 4 2149.074864 538.2749 "Keratin, type II cytoskeletal 1 OS=Homo sapiens OX=9606 GN=KRT1 PE=1 SV=6" 6.42 3960.1 - 90060.4 - - - 2.0367 - 1.239 0.255 - 23.4 1 2 0 0.0044 17 0 0 0 2.27E+06 0.00E+00 - - - 1.5187 1 221125_WJC_METTL3_EV_vs_WT_F07.25567.25567.3 4.43E-06 Aug-84 R.DNYVPEVSALDQEIIEVDPDTK.E "sp|P08708|RS17_HUMAN,tr|H3BNC9|H3BNC9_HUMAN,tr|H0YN88|H0YN88_HUMAN,tr|A0A075B716|A0A075B716_HUMAN" 4 2488.1857 2.15 108786 25567 3 2488.186773 830.4025 40S ribosomal protein S17 OS=Homo sapiens OX=9606 GN=RPS17 PE=1 SV=2 3.62 3963.9 - 260017 - - - 0.4332 - 1.962 0.589 - 36.9 1 2 0 0.0011 22 0 0 0 2.33E+06 1.09E+06 - - - 6.7043 0.9999 221125_WJC_METTL3_EV_vs_WT_F07.25568.25568.4 1.57E-12 42/204 K.QSKPVTTPEEIAQVATISANGDKEIGNIISDAMKK.V "sp|P10809|CH60_HUMAN,tr|A0A7I2V599|A0A7I2V599_HUMAN,tr|E7EXB4|E7EXB4_HUMAN,tr|A0A7I2YQ71|A0A7I2YQ71_HUMAN,tr|E7ESH4|E7ESH4_HUMAN,tr|A0A7I2V5M1|A0A7I2V5M1_HUMAN,tr|A0A7I2V5K3|A0A7I2V5K3_HUMAN,tr|A0A7I2V369|A0A7I2V369_HUMAN" 8 3682.9088 1.16 108787 25568 4 3682.908051 921.7345 "60 kDa heat shock protein, mitochondrial OS=Homo sapiens OX=9606 GN=HSPD1 PE=1 SV=2" 4.94 3964 - 1.66E+06 - - - -0.1914 - 6.058 0.606 - 935.8 1 2 1 -0.0007 35 0 0 0 1.92E+07 1.66E+07 - - - 5.0345 1 221125_WJC_METTL3_EV_vs_WT_F07.25572.25572.3 5.47E-15 25/84 R.KPLVIIAEDVDGEALSTLVLNR.L "sp|P10809|CH60_HUMAN,tr|A0A7I2V2X6|A0A7I2V2X6_HUMAN,tr|A0A7I2YQK6|A0A7I2YQK6_HUMAN,tr|A0A7I2V599|A0A7I2V599_HUMAN,tr|A0A7I2YQ71|A0A7I2YQ71_HUMAN,tr|A0A7I2V5M1|A0A7I2V5M1_HUMAN,tr|A0A7I2V5K3|A0A7I2V5K3_HUMAN" 7 2364.3264 0.64 108788 25572 3 2364.332689 789.1161 "60 kDa heat shock protein, mitochondrial OS=Homo sapiens OX=9606 GN=HSPD1 PE=1 SV=2" 4.32 3964.6 - 915222 - - - 2.6485 - 4.641 0.697 - 763.4 1 2 0 0.0063 22 0 0 0 7.84E+06 1.22E+07 - - - 9.9482 1 221125_WJC_METTL3_EV_vs_WT_F07.25574.25574.4 0.0465 33/162 R.HVDAHATLNDGVVVQVMGLLSNNNQALR.R "sp|Q13283|G3BP1_HUMAN,tr|A0A7I2YQB1|A0A7I2YQB1_HUMAN,tr|A0A7I2V5M7|A0A7I2V5M7_HUMAN,tr|E5RH42|E5RH42_HUMAN,tr|A0A7P0P2U7|A0A7P0P2U7_HUMAN,tr|A0A7I2YQU8|A0A7I2YQU8_HUMAN,tr|E5RJU8|E5RJU8_HUMAN,tr|A0A7I2V651|A0A7I2V651_HUMAN,tr|E5RIF8|E5RIF8_HUMAN,tr|A0A7I2YQN9|A0A7I2YQN9_HUMAN" 10 2984.525 1.23 108790 25574 4 2984.531279 747.1385 Ras GTPase-activating protein-binding protein 1 OS=Homo sapiens OX=9606 GN=G3BP1 PE=1 SV=1 5.98 3964.8 - 1.26E+06 - - - 2.0915 - 5.367 0.645 - 596 1 2 0 0.0062 28 0 0 0 1.02E+07 8.35E+06 - - - 5.36 0.9998 221125_WJC_METTL3_EV_vs_WT_F07.25575.25575.2 0.0183 22-Dec R.NLDLDSIIAEVK.A "sp|P48668|K2C6C_HUMAN,sp|P04259|K2C6B_HUMAN,sp|P13647|K2C5_HUMAN,sp|P35908|K22E_HUMAN,sp|O95678|K2C75_HUMAN,sp|Q5XKE5|K2C79_HUMAN,sp|P02538|K2C6A_HUMAN,tr|H0YI76|H0YI76_HUMAN,tr|H0YIN9|H0YIN9_HUMAN" 9 1328.7187 0.75 108791 25575 2 1328.720114 665.3666 "Keratin, type II cytoskeletal 6C OS=Homo sapiens OX=9606 GN=KRT6C PE=1 SV=3" 4.03 3965 - 1.03E+06 - - - 1.0288 - 2.238 0.435 - 333.9 1 2 0 0.0014 12 0 0 0 1.20E+07 1.60E+07 - - - 4.3731 1 221125_WJC_METTL3_EV_vs_WT_F07.25576.25576.3 5.94E-11 24/84 R.K[136.11]PLVIIAEDVDGEALSTLVLNR[166.11].L "sp|P10809|CH60_HUMAN,tr|A0A7I2V2X6|A0A7I2V2X6_HUMAN,tr|A0A7I2YQK6|A0A7I2YQK6_HUMAN,tr|A0A7I2V599|A0A7I2V599_HUMAN,tr|A0A7I2YQ71|A0A7I2YQ71_HUMAN,tr|A0A7I2V5M1|A0A7I2V5M1_HUMAN,tr|A0A7I2V5K3|A0A7I2V5K3_HUMAN" 7 2382.3489 0.67 108792 25576 3 2382.352694 795.1236 "60 kDa heat shock protein, mitochondrial OS=Homo sapiens OX=9606 GN=HSPD1 PE=1 SV=2" 4.32 3965.1 - 543554 - - - 1.5938 - 4.725 0.595 - 731.5 1 2 0 0.0038 22 0 0 0 8.48E+06 1.27E+07 - - - 8.8542 0.977 221125_WJC_METTL3_EV_vs_WT_F07.25580.25580.3 1.58E-05 15/80 K.R[166.11]R[166.11]AEQDSTTVAAFASSLVSGL.N "sp|Q86U44|MTA70_HUMAN,tr|F5H6D8|F5H6D8_HUMAN,tr|H0YFV6|H0YFV6_HUMAN,tr|B4DTN4|B4DTN4_HUMAN" 4 2185.1242 0.01 108794 25580 3 2185.127685 729.382 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 6.07 3965.7 - 332235 - - - 1.5949 - 2.571 0.504 - 240.9 1 1 1 0.0035 21 0 0 0 1.45E+05 1.23E+07 - - - 6.422 0.9981 221125_WJC_METTL3_EV_vs_WT_F07.25584.25584.4 0.000226 8/126 R.KPLVIIAEDVDGEALSTLVLNR.L "sp|P10809|CH60_HUMAN,tr|A0A7I2V2X6|A0A7I2V2X6_HUMAN,tr|A0A7I2YQK6|A0A7I2YQK6_HUMAN,tr|A0A7I2V599|A0A7I2V599_HUMAN,tr|A0A7I2YQ71|A0A7I2YQ71_HUMAN,tr|A0A7I2V5M1|A0A7I2V5M1_HUMAN,tr|A0A7I2V5K3|A0A7I2V5K3_HUMAN" 7 2364.3264 1.67 108798 25584 4 2364.335844 592.0889 "60 kDa heat shock protein, mitochondrial OS=Homo sapiens OX=9606 GN=HSPD1 PE=1 SV=2" 4.32 3966.2 - 124853 - - - 3.983 - 1.927 0.363 - 36.5 1 2 0 0.0094 22 0 0 0 8.19E+05 4.92E+05 - - - 2.5976 1 221125_WJC_METTL3_EV_vs_WT_F07.25590.25590.3 1.58E-10 14/68 K.YVHYEIDAC[160.03]MDSEAPGSK[136.11].D "sp|Q86U44|MTA70_HUMAN,tr|H0YFV6|H0YFV6_HUMAN" 2 2078.8805 0.03 108802 25590 3 2078.884168 693.9674 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 4.31 3967 - 216565 - - - 1.7683 - 3.024 0.708 - 227.3 1 2 0 0.0037 18 0 0 0 3.03E+05 1.04E+07 - - - 9.188 0.9999 221125_WJC_METTL3_EV_vs_WT_F07.25603.25603.4 1.54E-14 21/198 K.QSKPVTTPEEIAQVATISANGDKEIGNIISDAMK.K "sp|P10809|CH60_HUMAN,tr|A0A7I2V599|A0A7I2V599_HUMAN,tr|E7EXB4|E7EXB4_HUMAN,tr|A0A7I2YQ71|A0A7I2YQ71_HUMAN,tr|E7ESH4|E7ESH4_HUMAN,tr|A0A7I2V5M1|A0A7I2V5M1_HUMAN,tr|A0A7I2V5K3|A0A7I2V5K3_HUMAN,tr|A0A7I2V369|A0A7I2V369_HUMAN" 8 3554.8138 1.48 108810 25603 4 3554.809276 889.7107 "60 kDa heat shock protein, mitochondrial OS=Homo sapiens OX=9606 GN=HSPD1 PE=1 SV=2" 4.51 3968.7 - 387310 - - - -1.2707 - 4.756 0.598 - 216.3 1 2 1 -0.0045 34 0 0 0 4.47E+08 3.02E+08 - - - 4.8948 0.9999 221125_WJC_METTL3_EV_vs_WT_F07.25615.25615.4 2.13E-14 32/198 K.QSK[136.11]PVTTPEEIAQVATISANGDK[136.11]EIGNIISDAMK[136.11].K "sp|P10809|CH60_HUMAN,tr|A0A7I2V599|A0A7I2V599_HUMAN,tr|E7EXB4|E7EXB4_HUMAN,tr|A0A7I2YQ71|A0A7I2YQ71_HUMAN,tr|E7ESH4|E7ESH4_HUMAN,tr|A0A7I2V5M1|A0A7I2V5M1_HUMAN,tr|A0A7I2V5K3|A0A7I2V5K3_HUMAN,tr|A0A7I2V369|A0A7I2V369_HUMAN" 8 3578.8564 1.48 108815 25615 4 3578.856629 895.7214 "60 kDa heat shock protein, mitochondrial OS=Homo sapiens OX=9606 GN=HSPD1 PE=1 SV=2" 4.51 3970.5 - 547974 - - - 0.0659 - 5.274 0.602 - 423.1 1 2 1 0.0002 34 0 0 0 4.47E+08 3.02E+08 - - - 4.9616 0.9988 221125_WJC_METTL3_EV_vs_WT_F07.25636.25636.3 0.00432 Jun-68 R.GDADQASNILASFGLSAR.D "sp|P43243|MATR3_HUMAN,tr|A8MXP9|A8MXP9_HUMAN,tr|D6R991|D6R991_HUMAN,tr|A0A0R4J2E8|A0A0R4J2E8_HUMAN,tr|D6REM6|D6REM6_HUMAN" 5 1791.8751 1.39 108822 25636 3 1791.874717 598.299 Matrin-3 OS=Homo sapiens OX=9606 GN=MATR3 PE=1 SV=2 4.21 3973.2 - 130015 - - - -0.2366 - 1.462 0.329 - 45 1 2 0 -0.0004 18 0 0 0 3.74E+06 2.69E+06 - - - 3.1537 1 221125_WJC_METTL3_EV_vs_WT_F07.25642.25642.4 9.36E-09 15/162 K.DGNASGTTLLEALDC[160.03]ILPPTR[166.11]PTDK[136.11]PLR[166.11].L "sp|P68104|EF1A1_HUMAN,sp|Q5VTE0|EF1A3_HUMAN,tr|A0A7I2V659|A0A7I2V659_HUMAN,tr|A0A7I2V3H3|A0A7I2V3H3_HUMAN,tr|A0A7I2V5N4|A0A7I2V5N4_HUMAN,tr|A0A087WVQ9|A0A087WVQ9_HUMAN,tr|A0A087WV01|A0A087WV01_HUMAN" 7 3048.5908 0.3 108825 25642 4 3048.603216 763.155 Elongation factor 1-alpha 1 OS=Homo sapiens OX=9606 GN=EEF1A1 PE=1 SV=1 4.68 3974 - 433047 - - - 4.0645 - 3.058 0.64 - 87.1 1 2 0 0.0124 28 0 0 0 7.64E+07 2.58E+08 - - - 5.1402 1 221125_WJC_METTL3_EV_vs_WT_F07.25649.25649.4 3.56E-09 18/174 K.IVKPNGEKPDEFESGISQALLELEMNSDLK.A "sp|P62081|RS7_HUMAN,tr|B5MCP9|B5MCP9_HUMAN,tr|A0A2R8Y623|A0A2R8Y623_HUMAN" 3 3329.6701 2.79 108830 25649 4 3329.674922 833.4248 40S ribosomal protein S7 OS=Homo sapiens OX=9606 GN=RPS7 PE=1 SV=1 4.25 3975 - 513537 - - - 1.4515 - 3.319 0.519 - 183.8 1 2 0 0.0048 30 0 0 0 2.56E+07 9.19E+06 - - - 4.1091 1 221125_WJC_METTL3_EV_vs_WT_F07.25650.25650.4 5.23E-08 15/174 K.IVK[136.11]PNGEK[136.11]PDEFESGISQALLELEMNSDLK[136.11].A "sp|P62081|RS7_HUMAN,tr|B5MCP9|B5MCP9_HUMAN,tr|A0A2R8Y623|A0A2R8Y623_HUMAN" 3 3353.7127 2.79 108831 25650 4 3353.714152 839.4354 40S ribosomal protein S7 OS=Homo sapiens OX=9606 GN=RPS7 PE=1 SV=1 4.25 3975.1 - 345619 - - - 0.4362 - 3.175 0.555 - 141 1 2 0 0.0015 30 0 0 0 2.56E+07 9.19E+06 - - - 4.4098 1 221125_WJC_METTL3_EV_vs_WT_F07.25660.25660.4 5.94E-10 25/162 K.DGNASGTTLLEALDC[160.03]ILPPTRPTDKPLR.L "sp|P68104|EF1A1_HUMAN,sp|Q5VTE0|EF1A3_HUMAN,tr|A0A7I2V659|A0A7I2V659_HUMAN,tr|A0A7I2V3H3|A0A7I2V3H3_HUMAN,tr|A0A7I2V5N4|A0A7I2V5N4_HUMAN,tr|A0A087WVQ9|A0A087WVQ9_HUMAN,tr|A0A087WV01|A0A087WV01_HUMAN" 7 3020.5601 0.3 108835 25660 4 3020.559686 756.1473 Elongation factor 1-alpha 1 OS=Homo sapiens OX=9606 GN=EEF1A1 PE=1 SV=1 4.68 3976.4 - 765433 - - - -0.1321 - 3.797 0.677 - 279.7 1 2 0 -0.0004 28 0 0 0 7.64E+07 2.58E+08 - - - 5.5327 0.9906 221125_WJC_METTL3_EV_vs_WT_F07.25662.25662.3 1.16E-07 13/124 R.AEQDSTTVAAFASSLVSGLNSSASEPAK[136.11]EPAK[136.11].K "sp|Q86U44|MTA70_HUMAN,tr|F5H6D8|F5H6D8_HUMAN,tr|H0YFV6|H0YFV6_HUMAN,tr|B4DTN4|B4DTN4_HUMAN" 4 3165.5648 0.001 108836 25662 3 3166.560222 1056.1956 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 4.41 3976.7 - 342889 - - - 314.4431 - 2.53 0.559 - 103.7 1 2 1 0.9954 32 0 0 0 0.00E+00 8.26E+06 - - - 6.6321 1 221125_WJC_METTL3_EV_vs_WT_F07.25665.25665.3 3.57E-18 21/132 R.TDADSESDNSDNNTIFVQGLGEGVSTDQVGEFFK.Q "sp|Q92804|RBP56_HUMAN,tr|A0A075B7D9|A0A075B7D9_HUMAN" 2 3621.5867 2.65 108837 25665 3 3621.584976 1208.2028 TATA-binding protein-associated factor 2N OS=Homo sapiens OX=9606 GN=TAF15 PE=1 SV=1 3.54 3977.1 - 1.07E+06 - - - -0.4733 - 4.287 0.818 - 308.4 1 2 0 -0.0017 34 0 0 0 2.11E+07 7.96E+06 - - - 11.0082 1 221125_WJC_METTL3_EV_vs_WT_F07.25666.25666.3 2.72E-17 21/132 R.TDADSESDNSDNNTIFVQGLGEGVSTDQVGEFFK[136.11].Q "sp|Q92804|RBP56_HUMAN,tr|A0A075B7D9|A0A075B7D9_HUMAN" 2 3629.6009 2.65 108838 25666 3 3629.589653 1210.8742 TATA-binding protein-associated factor 2N OS=Homo sapiens OX=9606 GN=TAF15 PE=1 SV=1 3.54 3977.2 - 849441 - - - -3.0959 - 3.972 0.822 - 273.6 1 2 0 -0.0112 34 0 0 0 2.11E+07 7.96E+06 - - - 10.8746 1 221125_WJC_METTL3_EV_vs_WT_F07.25667.25667.3 1.77E-10 25/132 K.QSKPVTTPEEIAQVATISANGDKEIGNIISDAMK.K "sp|P10809|CH60_HUMAN,tr|A0A7I2V599|A0A7I2V599_HUMAN,tr|E7EXB4|E7EXB4_HUMAN,tr|A0A7I2YQ71|A0A7I2YQ71_HUMAN,tr|E7ESH4|E7ESH4_HUMAN,tr|A0A7I2V5M1|A0A7I2V5M1_HUMAN,tr|A0A7I2V5K3|A0A7I2V5K3_HUMAN,tr|A0A7I2V369|A0A7I2V369_HUMAN" 8 3554.8138 1.85 108839 25667 3 3554.814203 1185.9452 "60 kDa heat shock protein, mitochondrial OS=Homo sapiens OX=9606 GN=HSPD1 PE=1 SV=2" 4.51 3977.3 - 527930 - - - 0.1153 - 4.325 0.622 - 318.9 1 2 1 0.0004 34 0 0 0 1.43E+07 7.73E+06 - - - 8.8437 1 221125_WJC_METTL3_EV_vs_WT_F07.25686.25686.3 3.26E-06 20/108 K.DGNASGTTLLEALDC[160.03]ILPPTR[166.11]PTDK[136.11]PLR[166.11].L "sp|P68104|EF1A1_HUMAN,sp|Q5VTE0|EF1A3_HUMAN,tr|A0A7I2V659|A0A7I2V659_HUMAN,tr|A0A7I2V3H3|A0A7I2V3H3_HUMAN,tr|A0A7I2V5N4|A0A7I2V5N4_HUMAN,tr|A0A087WVQ9|A0A087WVQ9_HUMAN,tr|A0A087WV01|A0A087WV01_HUMAN" 7 3048.5908 0.23 108843 25686 3 3048.58873 1017.2042 Elongation factor 1-alpha 1 OS=Homo sapiens OX=9606 GN=EEF1A1 PE=1 SV=1 4.68 3980 - 1.31E+06 - - - -0.6872 - 2.89 0.59 - 195.4 1 2 0 -0.0021 28 0 0 0 6.13E+06 2.67E+07 - - - 7.5589 1 221125_WJC_METTL3_EV_vs_WT_F07.25721.25721.4 3.59E-11 24/162 R.HVDAHATLNDGVVVQVMGLLSNNNQALR[166.11].R "sp|Q13283|G3BP1_HUMAN,tr|A0A7I2YQB1|A0A7I2YQB1_HUMAN,tr|A0A7I2V5M7|A0A7I2V5M7_HUMAN,tr|E5RH42|E5RH42_HUMAN,tr|A0A7P0P2U7|A0A7P0P2U7_HUMAN,tr|A0A7I2YQU8|A0A7I2YQU8_HUMAN,tr|E5RJU8|E5RJU8_HUMAN,tr|A0A7I2V651|A0A7I2V651_HUMAN,tr|E5RIF8|E5RIF8_HUMAN,tr|A0A7I2YQN9|A0A7I2YQN9_HUMAN" 10 2994.5333 1.15 108854 25721 4 2994.531355 749.6406 Ras GTPase-activating protein-binding protein 1 OS=Homo sapiens OX=9606 GN=G3BP1 PE=1 SV=1 5.98 3984.9 - 469355 - - - -0.6519 - 3.552 0.5 - 346.3 1 2 0 -0.002 28 0 0 0 3.90E+06 3.40E+06 - - - 3.971 0.9824 221125_WJC_METTL3_EV_vs_WT_F07.25733.25733.2 0.0572 26-Jul R.ISLPLPNFSSLNLR.E "sp|P08670|VIME_HUMAN,tr|B0YJC4|B0YJC4_HUMAN" 2 1569.8879 2.96 108862 25733 2 1569.89003 785.9512 Vimentin OS=Homo sapiens OX=9606 GN=VIM PE=1 SV=4 9.75 3986.5 - 99882.9 - - - 1.3708 - 1.404 0.089 - 96.3 1 2 0 0.0022 14 0 0 0 2.33E+06 7.89E+05 - - - 0.5492 1 221125_WJC_METTL3_EV_vs_WT_F07.25757.25757.4 0.00014 8/108 R.GLLQDDAHPTLVTYADHSK[136.11].L "sp|Q86U44|MTA70_HUMAN,tr|F5H6D8|F5H6D8_HUMAN,tr|H0YFV6|H0YFV6_HUMAN,tr|B4DTN4|B4DTN4_HUMAN" 4 2088.0367 0.001 108873 25757 4 2088.036824 523.0165 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 5.13 3989.6 - 175231 - - - 0.0436 - 2.094 0.527 - 50.1 1 2 0 0.0001 19 0 0 0 0.00E+00 7.13E+06 - - - 4.063 0.9783 221125_WJC_METTL3_EV_vs_WT_F07.25759.25759.4 2.90E-06 9/186 K.GPAAIQKNYSPYYNTIDDLKDQIVDLTVGNNK.T sp|P35527|K1C9_HUMAN 1 3566.7893 26.19 108874 25759 4 3567.782354 892.7046 "Keratin, type I cytoskeletal 9 OS=Homo sapiens OX=9606 GN=KRT9 PE=1 SV=3" 4.58 3989.8 - 273566 - - - 278.4187 - 2.052 0.497 - 24.2 1 2 2 0.9931 32 0 0 0 3.08E+06 1.18E+05 - - - 3.4938 0.9998 221125_WJC_METTL3_EV_vs_WT_F07.25763.25763.4 3.44E-06 10/150 R.DFEGAVDLLDKLNHYLEDKPSPPPVK.E sp|Q8IYI6|EXOC8_HUMAN 1 2935.4967 3.72 108876 25763 4 2935.496746 734.8815 Exocyst complex component 8 OS=Homo sapiens OX=9606 GN=EXOC8 PE=1 SV=2 4.52 3990.5 - 246043 - - - 0.002 - 1.926 0.505 - 25.3 1 2 1 0 26 0 0 0 4.78E+06 1.28E+06 - - - 3.8283 0.9943 221125_WJC_METTL3_EV_vs_WT_F07.25774.25774.3 0.159 Dec-80 N.WITLGNQLDGIHLLDPDVVAR[166.11].F sp|Q86U44|MTA70_HUMAN 1 2354.2622 0.001 108879 25774 3 2354.262582 785.7613 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 4.41 3992.1 - 399285 - - - 0.1623 - 2.379 0.466 - 96.5 1 1 0 0.0004 21 0 0 0 0.00E+00 6.35E+06 - - - 5.8132 1 221125_WJC_METTL3_EV_vs_WT_F07.25790.25790.4 5.59E-12 20/210 K.TC[160.03]NC[160.03]ETEDYGEKFDENDVITC[160.03]FANFESDEVELSYAK.N "sp|Q00839|HNRPU_HUMAN,tr|A0A1W2PQL0|A0A1W2PQL0_HUMAN,tr|A0A1W2PPL4|A0A1W2PPL4_HUMAN,tr|A0A1W2PQ74|A0A1W2PQ74_HUMAN,tr|Q5RI18|Q5RI18_HUMAN,tr|A0A1W2PP35|A0A1W2PP35_HUMAN,tr|A0A1W2PPS1|A0A1W2PPS1_HUMAN,tr|A0A1W2PRZ7|A0A1W2PRZ7_HUMAN,tr|A0A1W2PPH7|A0A1W2PPH7_HUMAN,tr|A0A1W2PP34|A0A1W2PP34_HUMAN,tr|A0A1X7SBS1|A0A1X7SBS1_HUMAN" 11 4327.7668 0.75 108882 25790 4 4327.764812 1082.949 Heterogeneous nuclear ribonucleoprotein U OS=Homo sapiens OX=9606 GN=HNRNPU PE=1 SV=6 3.73 3994.6 - 690323 - - - -0.4552 - 3.85 0.84 - 164.9 1 2 1 -0.002 36 0 0 0 1.12E+07 1.48E+07 - - - 6.9342 1 221125_WJC_METTL3_EV_vs_WT_F07.25795.25795.3 6.82E-14 15/140 K.TC[160.03]NC[160.03]ETEDYGEKFDENDVITC[160.03]FANFESDEVELSYAK.N "sp|Q00839|HNRPU_HUMAN,tr|A0A1W2PQL0|A0A1W2PQL0_HUMAN,tr|A0A1W2PPL4|A0A1W2PPL4_HUMAN,tr|A0A1W2PQ74|A0A1W2PQ74_HUMAN,tr|Q5RI18|Q5RI18_HUMAN,tr|A0A1W2PP35|A0A1W2PP35_HUMAN,tr|A0A1W2PPS1|A0A1W2PPS1_HUMAN,tr|A0A1W2PRZ7|A0A1W2PRZ7_HUMAN,tr|A0A1W2PPH7|A0A1W2PPH7_HUMAN,tr|A0A1W2PP34|A0A1W2PP34_HUMAN,tr|A0A1X7SBS1|A0A1X7SBS1_HUMAN" 11 4327.7668 1.26 108884 25795 3 4327.76656 1443.5962 Heterogeneous nuclear ribonucleoprotein U OS=Homo sapiens OX=9606 GN=HNRNPU PE=1 SV=6 3.73 3995.2 - 402807 - - - -0.0513 - 3.303 0.862 - 153.3 1 2 1 -0.0002 36 0 0 0 4.44E+06 3.52E+06 - - - 10.8993 0.9992 221125_WJC_METTL3_EV_vs_WT_F07.25797.25797.2 9.52E-05 30-Aug K.AAGVNVEPFWPGLFAK.A sp|P05386|RLA1_HUMAN 1 1701.8879 4.18 108885 25797 2 1701.891645 851.9512 60S acidic ribosomal protein P1 OS=Homo sapiens OX=9606 GN=RPLP1 PE=1 SV=1 6.05 3995.5 - 125464 - - - 2.2134 - 1.514 0.474 - 143.6 1 2 0 0.0038 16 0 0 0 1.94E+06 4.64E+05 - - - 3.5605 0.8415 221125_WJC_METTL3_EV_vs_WT_F07.25808.25808.3 6.14E-05 14/96 R.R[166.11]AEQDSTTVAAFASSLVSGLNSSAS.E "sp|Q86U44|MTA70_HUMAN,tr|F5H6D8|F5H6D8_HUMAN,tr|H0YFV6|H0YFV6_HUMAN,tr|B4DTN4|B4DTN4_HUMAN" 4 2465.1909 0.43 108892 25808 3 2465.209622 822.7376 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 4.37 3997 - 355016 - - - 7.5759 - 2.896 0.525 - 166.8 1 1 0 0.0187 25 0 0 0 8.72E+05 2.01E+06 - - - 6.8344 1 221125_WJC_METTL3_EV_vs_WT_F07.25809.25809.4 8.72E-15 40/270 A.ASSPPAGPPPPPAPALVGLPPPPPSPPGFTLPPLGGSLGAGTSTSR.S "sp|O96008|TOM40_HUMAN,tr|K7EJ57|K7EJ57_HUMAN" 2 4215.2368 2.14 108893 25809 4 4215.244562 1054.8165 Mitochondrial import receptor subunit TOM40 homolog OS=Homo sapiens OX=9606 GN=TOMM40 PE=1 SV=1 9.79 3997.2 - 311214 - - - 1.8341 - 5.403 0.717 - 456.7 1 1 0 0.0077 46 0 0 0 1.83E+07 8.58E+06 - - - 5.9385 1 221125_WJC_METTL3_EV_vs_WT_F07.25810.25810.4 3.26E-10 23/210 K.YVAGETNAKENENSSPVAGAFGVFSTISTAVQSTGK.S "sp|Q9NRY5|F1142_HUMAN,tr|E7ESJ7|E7ESJ7_HUMAN,tr|E5RGF9|E5RGF9_HUMAN" 3 3617.7485 1.08 108894 25810 4 3617.748486 905.4444 Protein FAM114A2 OS=Homo sapiens OX=9606 GN=FAM114A2 PE=1 SV=4 4.79 3997.3 - 285470 - - - -0.0177 - 4.093 0.714 - 203.5 1 2 1 -0.0001 36 0 0 0 4.09E+06 3.79E+06 - - - 5.8561 0.9999 221125_WJC_METTL3_EV_vs_WT_F07.25814.25814.3 4.93E-08 10/140 K.YVAGETNAK[136.11]ENENSSPVAGAFGVFSTISTAVQSTGK[136.11].S "sp|Q9NRY5|F1142_HUMAN,tr|E7ESJ7|E7ESJ7_HUMAN,tr|E5RGF9|E5RGF9_HUMAN" 3 3633.7769 1.19 108896 25814 3 3633.77269 1212.2663 Protein FAM114A2 OS=Homo sapiens OX=9606 GN=FAM114A2 PE=1 SV=4 4.79 3997.8 - 108696 - - - -1.1723 - 2.669 0.647 - 60.8 1 2 1 -0.0043 36 0 0 0 9.01E+05 7.58E+05 - - - 8.0108 0.9999 221125_WJC_METTL3_EV_vs_WT_F07.25817.25817.4 2.37E-08 27/210 K.DGNASGTTLLEALDC[160.03]ILPPTRPTDKPLRLPLQDVYK.L "sp|P68104|EF1A1_HUMAN,sp|Q5VTE0|EF1A3_HUMAN,tr|A0A7I2V659|A0A7I2V659_HUMAN,tr|A0A7I2V3H3|A0A7I2V3H3_HUMAN,tr|A0A7I2V5N4|A0A7I2V5N4_HUMAN,tr|A0A087WVQ9|A0A087WVQ9_HUMAN,tr|A0A087WV01|A0A087WV01_HUMAN" 7 3977.0932 0.25 108899 25817 4 3977.097433 995.2806 Elongation factor 1-alpha 1 OS=Homo sapiens OX=9606 GN=EEF1A1 PE=1 SV=1 4.78 3998.2 - 1.27E+06 - - - 1.0636 - 4.305 0.615 - 298.8 1 2 1 0.0042 36 0 0 0 6.12E+06 2.43E+07 - - - 5.0081 1 221125_WJC_METTL3_EV_vs_WT_F07.25823.25823.4 2.65E-12 36/270 A.ASSPPAGPPPPPAPALVGLPPPPPSPPGFTLPPLGGSLGAGTSTSR[166.11].S "sp|O96008|TOM40_HUMAN,tr|K7EJ57|K7EJ57_HUMAN" 2 4225.2451 2.14 108903 25823 4 4225.244091 1057.3186 Mitochondrial import receptor subunit TOM40 homolog OS=Homo sapiens OX=9606 GN=TOMM40 PE=1 SV=1 9.79 3999 - 843680 - - - -0.239 - 5.086 0.619 - 351.9 1 1 0 -0.001 46 0 0 0 1.83E+07 8.58E+06 - - - 5.0704 0.9993 221125_WJC_METTL3_EV_vs_WT_F07.25825.25825.3 6.44E-05 Aug-64 K.ATENDIYNFFSPLNPVR.V "sp|P52597|HNRPF_HUMAN,sp|P31943|HNRH1_HUMAN,tr|H0YBD7|H0YBD7_HUMAN,tr|H0YB39|H0YB39_HUMAN,tr|H0YBG7|H0YBG7_HUMAN,tr|E9PCY7|E9PCY7_HUMAN,tr|G8JLB6|G8JLB6_HUMAN" 7 1995.969 1.18 108905 25825 3 1995.976363 666.3303 Heterogeneous nuclear ribonucleoprotein F OS=Homo sapiens OX=9606 GN=HNRNPF PE=1 SV=3 4.37 3999.3 - 149353 - - - 3.6684 - 1.929 0.443 - 73.3 1 2 0 0.0073 17 0 0 0 7.62E+05 6.45E+05 - - - 5.1368 1 221125_WJC_METTL3_EV_vs_WT_F07.25839.25839.3 3.72E-13 16/88 K.SINPDEAVAYGAAVQAAILSGDK[136.11].S "sp|P11142|HSP7C_HUMAN,tr|E9PNE6|E9PNE6_HUMAN,tr|A8K7Q2|A8K7Q2_HUMAN,tr|E9PKE3|E9PKE3_HUMAN" 4 2267.1525 0.12 108915 25839 3 2267.159509 756.7248 Heat shock cognate 71 kDa protein OS=Homo sapiens OX=9606 GN=HSPA8 PE=1 SV=1 4.03 4001.2 - 184773 - - - 3.0951 - 3.234 0.68 - 266 1 2 0 0.007 23 0 0 0 1.92E+05 1.64E+06 - - - 8.8729 1 221125_WJC_METTL3_EV_vs_WT_F07.25847.25847.4 1.21E-09 24/210 K.DGNASGTTLLEALDC[160.03]ILPPTR[166.11]PTDK[136.11]PLR[166.11]LPLQDVYK[136.11].L "sp|P68104|EF1A1_HUMAN,sp|Q5VTE0|EF1A3_HUMAN,tr|A0A7I2V659|A0A7I2V659_HUMAN,tr|A0A7I2V3H3|A0A7I2V3H3_HUMAN,tr|A0A7I2V5N4|A0A7I2V5N4_HUMAN,tr|A0A087WVQ9|A0A087WVQ9_HUMAN,tr|A0A087WV01|A0A087WV01_HUMAN" 7 4013.1381 0.25 108921 25847 4 4013.141784 1004.2918 Elongation factor 1-alpha 1 OS=Homo sapiens OX=9606 GN=EEF1A1 PE=1 SV=1 4.78 4002.3 - 330942 - - - 0.9073 - 4.294 0.643 - 254.3 1 2 1 0.0036 36 0 0 0 6.12E+06 2.43E+07 - - - 5.2512 0.8831 221125_WJC_METTL3_EV_vs_WT_F07.25851.25851.3 7.80E-06 10/100 H.NVQPNWITLGNQLDGIHLLDPDVVAR[166.11].F sp|Q86U44|MTA70_HUMAN 1 2906.5278 0.01 108923 25851 3 2907.530405 969.8499 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 4.41 4002.8 - 339294 - - - 344.9456 - 2.682 0.478 - 44.1 1 1 0 1.0026 26 0 0 0 3.69E+05 2.68E+07 - - - 5.8612 0.9516 221125_WJC_METTL3_EV_vs_WT_F07.25866.25866.3 4.73E-08 15/108 R.R[166.11]AEQDSTTVAAFASSLVSGLNSSASEPA.K "sp|Q86U44|MTA70_HUMAN,tr|F5H6D8|F5H6D8_HUMAN,tr|H0YFV6|H0YFV6_HUMAN,tr|B4DTN4|B4DTN4_HUMAN" 4 2762.3234 0.08 108929 25866 3 2763.328254 921.7817 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 4.14 4004.7 - 344976 - - - 363.7655 - 3.011 0.575 - 203.7 1 1 0 1.0048 28 0 0 0 4.98E+05 5.94E+06 - - - 7.2083 1 221125_WJC_METTL3_EV_vs_WT_F07.25871.25871.3 9.94E-10 26/108 R.AEQDSTTVAAFASSLVSGLNSSASEPAK[136.11].E "sp|Q86U44|MTA70_HUMAN,tr|F5H6D8|F5H6D8_HUMAN,tr|H0YFV6|H0YFV6_HUMAN,tr|B4DTN4|B4DTN4_HUMAN" 4 2732.3232 0.02 108931 25871 3 2733.325741 911.7817 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 4.14 4005.6 - 522130 - - - 366.9196 - 4.815 0.681 - 520.7 1 2 0 1.0025 28 0 0 0 1.55E+05 1.01E+07 - - - 9.4708 0.9991 221125_WJC_METTL3_EV_vs_WT_F07.25877.25877.4 3.26E-07 13/144 K.NYSPYYNTIDDLKDQIVDLTVGNNK.T sp|P35527|K1C9_HUMAN 1 2901.4032 23.6 108935 25877 4 2901.415302 726.3581 "Keratin, type I cytoskeletal 9 OS=Homo sapiens OX=9606 GN=KRT9 PE=1 SV=3" 4.14 4006.3 - 319110 - - - 4.1597 - 2.566 0.52 - 81.5 1 2 1 0.0121 25 0 0 0 1.63E+06 6.92E+04 - - - 4.0485 0.9992 221125_WJC_METTL3_EV_vs_WT_F07.25878.25878.3 3.08E-06 Dec-84 R.TLTAVHDAILEDLVFPSEIVGK.R "sp|P62081|RS7_HUMAN,tr|B5MCP9|B5MCP9_HUMAN,tr|A0A2R8Y623|A0A2R8Y623_HUMAN" 3 2366.2733 1.04 108936 25878 3 2366.289806 789.7651 40S ribosomal protein S7 OS=Homo sapiens OX=9606 GN=RPS7 PE=1 SV=1 4.31 4006.4 - 130929 - - - 6.9633 - 2.543 0.614 - 132.3 1 2 0 0.0165 22 0 0 0 5.92E+05 5.72E+05 - - - 7.5937 0.9978 221125_WJC_METTL3_EV_vs_WT_F07.25884.25884.4 3.56E-06 16/186 R.HDSEQDNSDNNTIFVQGLGENVTIESVADYFK.Q sp|P35637|FUS_HUMAN 1 3584.6179 -1 108939 25884 4 3584.634935 897.1618 RNA-binding protein FUS OS=Homo sapiens OX=9606 GN=FUS PE=1 SV=1 3.9 4007.2 - 465605 - - - 4.7439 - 2.879 0.377 - 66.6 1 2 0 0.017 32 0 0 0 0.00E+00 0.00E+00 - - - 2.822 1 221125_WJC_METTL3_EV_vs_WT_F07.25886.25886.3 1.62E-26 33/124 R.HDSEQDNSDNNTIFVQGLGENVTIESVADYFK.Q sp|P35637|FUS_HUMAN 1 3584.6179 -1 108941 25886 3 3584.631709 1195.8799 RNA-binding protein FUS OS=Homo sapiens OX=9606 GN=FUS PE=1 SV=1 3.9 4007.5 - 366831 - - - 3.8439 - 5.75 0.85 - 1293.3 1 2 0 0.0138 32 0 0 0 0.00E+00 0.00E+00 - - - 12.0371 0.9998 221125_WJC_METTL3_EV_vs_WT_F07.27186.27186.4 0.000125 Dec-84 R.VLSAPPHFHFGQTNR.T sp|P26641|EF1G_HUMAN 1 1706.8641 0.93 109091 27186 4 1706.866331 427.7233 Elongation factor 1-gamma OS=Homo sapiens OX=9606 GN=EEF1G PE=1 SV=3 9.73 4250 - 121225 - - - 1.2936 - 2.415 0.377 - 154.3 1 2 0 0.0022 15 0 0 0 1.83E+06 1.97E+06 - - - 2.8223 1 221125_WJC_METTL3_EV_vs_WT_F07.27187.27187.4 0.000764 Dec-84 R.VLSAPPHFHFGQTNR[166.11].T sp|P26641|EF1G_HUMAN 1 1716.8724 0.93 109092 27187 4 1716.873747 430.2254 Elongation factor 1-gamma OS=Homo sapiens OX=9606 GN=EEF1G PE=1 SV=3 9.73 4250.1 - 136210 - - - 0.7886 - 2.557 0.561 - 93.3 1 2 0 0.0014 15 0 0 0 1.81E+06 1.95E+06 - - - 4.4445 0.9984 221125_WJC_METTL3_EV_vs_WT_F08.02377.02377.2 0.000374 16-Aug K.TATAVAHC[160.03]K[136.11].R "sp|P62249|RS16_HUMAN,tr|M0R210|M0R210_HUMAN,tr|M0R3H0|M0R3H0_HUMAN,tr|M0R1M5|M0R1M5_HUMAN,tr|Q6IPX4|Q6IPX4_HUMAN" 5 965.4844 0.9 109138 2377 2 965.480484 483.7495 40S ribosomal protein S16 OS=Homo sapiens OX=9606 GN=RPS16 PE=1 SV=2 7.92 1178 - 3.90E+07 - - - -4.056 - 1.78 0.493 - 238.6 1 2 0 -0.0039 9 0 0 0 1.49E+08 1.65E+08 - - - 4.3492 0.999 221125_WJC_METTL3_EV_vs_WT_F08.02378.02378.2 0.000471 16-Sep K.TATAVAHC[160.03]K.R "sp|P62249|RS16_HUMAN,tr|M0R210|M0R210_HUMAN,tr|M0R3H0|M0R3H0_HUMAN,tr|M0R1M5|M0R1M5_HUMAN,tr|Q6IPX4|Q6IPX4_HUMAN" 5 957.4702 0.9 109139 2378 2 957.46647 479.7424 40S ribosomal protein S16 OS=Homo sapiens OX=9606 GN=RPS16 PE=1 SV=2 7.92 1178 - 3.09E+07 - - - -3.8957 - 1.961 0.541 - 311.1 1 2 0 -0.0037 9 0 0 0 1.49E+08 1.65E+08 - - - 4.984 0.8743 221125_WJC_METTL3_EV_vs_WT_F08.02379.02379.2 0.0146 16-Dec A.GAHLQGGAK[136.11].R "sp|P04406|G3P_HUMAN,tr|E7EUT5|E7EUT5_HUMAN" 2 845.4599 1.04 109140 2379 2 845.455963 423.7372 Glyceraldehyde-3-phosphate dehydrogenase OS=Homo sapiens OX=9606 GN=GAPDH PE=1 SV=3 8.76 1178.1 - 2.40E+07 - - - -4.6566 - 2.116 0.433 - 584.8 1 1 0 -0.0039 9 0 0 0 7.22E+09 6.96E+09 - - - 4.4063 0.9977 221125_WJC_METTL3_EV_vs_WT_F08.02380.02380.2 0.37 14/18 K.AGAHLQGGAK[136.11].R "sp|P04406|G3P_HUMAN,tr|E7EUT5|E7EUT5_HUMAN" 2 916.497 1.19 109141 2380 2 916.492644 459.2558 Glyceraldehyde-3-phosphate dehydrogenase OS=Homo sapiens OX=9606 GN=GAPDH PE=1 SV=3 8.8 1178.1 - 2.30E+07 - - - -4.7682 - 2.542 0.397 - 948.8 1 2 0 -0.0044 10 0 0 0 7.14E+09 6.00E+09 - - - 4.576 0.8716 221125_WJC_METTL3_EV_vs_WT_F08.02381.02381.2 0.0572 13/16 A.GAHLQGGAK.R "sp|P04406|G3P_HUMAN,tr|E7EUT5|E7EUT5_HUMAN" 2 837.4457 1.04 109142 2381 2 837.441663 419.7301 Glyceraldehyde-3-phosphate dehydrogenase OS=Homo sapiens OX=9606 GN=GAPDH PE=1 SV=3 8.76 1178.2 - 1.93E+07 - - - -4.8206 - 2.372 0.408 - 627 1 1 0 -0.004 9 0 0 0 7.22E+09 6.96E+09 - - - 4.552 0.8894 221125_WJC_METTL3_EV_vs_WT_F08.02384.02384.2 0.0218 16-Jul K.ANSQPSAGR.A "sp|P15927|RFA2_HUMAN,tr|Q5TEJ0|Q5TEJ0_HUMAN" 2 886.4257 1.28 109145 2384 2 886.420964 444.2201 Replication protein A 32 kDa subunit OS=Homo sapiens OX=9606 GN=RPA2 PE=1 SV=1 9.79 1178.3 - 1.22E+07 - - - -5.3349 - 1.728 0.082 - 163 2 2 0 -0.0047 9 0 0 0 3.56E+08 2.78E+08 - - - 1.0931 0.9898 221125_WJC_METTL3_EV_vs_WT_F08.02387.02387.2 0.196 16-Sep K.ANSQPSAGR[166.11].A "sp|P15927|RFA2_HUMAN,tr|Q5TEJ0|Q5TEJ0_HUMAN" 2 896.434 1.28 109148 2387 2 896.430212 449.2243 Replication protein A 32 kDa subunit OS=Homo sapiens OX=9606 GN=RPA2 PE=1 SV=1 9.79 1178.4 - 9.60E+06 - - - -4.1844 - 1.882 0.208 - 300.2 1 2 0 -0.0037 9 0 0 0 3.60E+08 2.81E+08 - - - 2.4055 0.9931 221125_WJC_METTL3_EV_vs_WT_F08.02392.02392.2 0.0277 12-Sep K.KEPVTTR.Q "sp|Q04695|K1C17_HUMAN,tr|F5GWP8|F5GWP8_HUMAN" 2 829.4658 999 109153 2392 2 829.461995 415.7402 "Keratin, type I cytoskeletal 17 OS=Homo sapiens OX=9606 GN=KRT17 PE=1 SV=2" 8.75 1178.6 - 3.24E+06 - - - -4.5475 - 1.627 0.33 - 370 1 2 0 -0.0038 7 0 0 0 5.10E+08 0.00E+00 - - - 3.0195 0.9976 221125_WJC_METTL3_EV_vs_WT_F08.02394.02394.2 0.000294 16-Oct K.TEGTPNQGK[136.11].K "sp|Q9P2E9|RRBP1_HUMAN,tr|A2A2S5|A2A2S5_HUMAN,tr|A0A087WVV2|A0A087WVV2_HUMAN" 3 938.4549 3.74 109155 2394 2 938.451374 470.2347 Ribosome-binding protein 1 OS=Homo sapiens OX=9606 GN=RRBP1 PE=1 SV=5 5.66 1178.8 - 1.38E+06 - - - -3.7295 - 1.629 0.417 - 434.8 1 2 0 -0.0035 9 0 0 0 3.43E+07 9.18E+06 - - - 3.5316 0.9989 221125_WJC_METTL3_EV_vs_WT_F08.02400.02400.2 0.000596 14/18 K.AGAHLQGGAK.R "sp|P04406|G3P_HUMAN,tr|E7EUT5|E7EUT5_HUMAN" 2 908.4828 1.19 109160 2400 2 908.478896 455.2487 Glyceraldehyde-3-phosphate dehydrogenase OS=Homo sapiens OX=9606 GN=GAPDH PE=1 SV=3 8.8 1179.4 - 7.68E+07 - - - -4.3127 - 2.464 0.514 - 897.7 1 2 0 -0.0039 10 0 0 0 7.14E+09 6.00E+09 - - - 5.3533 0.8008 221125_WJC_METTL3_EV_vs_WT_F08.02401.02401.2 3.16 14-Apr K.EGPAHEPK[136.11].F "sp|P55265|DSRAD_HUMAN,tr|A0A3B3ITG9|A0A3B3ITG9_HUMAN,tr|A0A3B3IRQ9|A0A3B3IRQ9_HUMAN,tr|A0A3B3ISU1|A0A3B3ISU1_HUMAN,tr|A0A7P0Z4K3|A0A7P0Z4K3_HUMAN,tr|A0A3B3ISX1|A0A3B3ISX1_HUMAN,tr|A0A7P0Z4F9|A0A7P0Z4F9_HUMAN" 7 871.4279 1.41 109161 2401 2 871.424841 436.7212 Double-stranded RNA-specific adenosine deaminase OS=Homo sapiens OX=9606 GN=ADAR PE=1 SV=4 5.4 1179.4 - 1.21E+06 - - - -3.5459 - 0.935 0.164 - 58.3 4 2 0 -0.0031 8 0 0 0 5.67E+07 4.03E+07 - - - -0.2203 0.9125 221125_WJC_METTL3_EV_vs_WT_F08.02405.02405.2 4.22E-05 14-Nov V.HAITATQK[136.11].T "sp|P04406|G3P_HUMAN,tr|E7EUT5|E7EUT5_HUMAN" 2 876.4909 1.08 109163 2405 2 876.487011 439.2527 Glyceraldehyde-3-phosphate dehydrogenase OS=Homo sapiens OX=9606 GN=GAPDH PE=1 SV=3 8.76 1179.9 - 4.16E+06 - - - -4.3982 - 2.2 0.452 - 410.7 1 1 0 -0.0039 8 0 0 0 2.48E+08 2.28E+08 - - - 4.7562 0.8281 221125_WJC_METTL3_EV_vs_WT_F08.02406.02406.2 0.00244 14-Nov V.HAITATQK.T "sp|P04406|G3P_HUMAN,tr|E7EUT5|E7EUT5_HUMAN" 2 868.4767 1.08 109164 2406 2 868.471857 435.2456 Glyceraldehyde-3-phosphate dehydrogenase OS=Homo sapiens OX=9606 GN=GAPDH PE=1 SV=3 8.76 1179.9 - 4.60E+06 - - - -5.5373 - 2.201 0.462 - 402.3 1 1 0 -0.0048 8 0 0 0 2.48E+08 2.28E+08 - - - 4.8311 0.9477 221125_WJC_METTL3_EV_vs_WT_F08.02407.02407.2 0.574 14-Oct R.RTGC[160.03]IGAK.H "sp|P62913|RL11_HUMAN,tr|Q5VVC8|Q5VVC8_HUMAN" 2 861.4491 1.23 109165 2407 2 861.444586 431.7318 60S ribosomal protein L11 OS=Homo sapiens OX=9606 GN=RPL11 PE=1 SV=2 9.51 1180 - 3.78E+06 - - - -5.2063 - 1.529 0.177 - 385.2 1 2 0 -0.0045 8 0 0 0 1.74E+08 1.41E+08 - - - 1.6275 0.9561 221125_WJC_METTL3_EV_vs_WT_F08.02417.02417.2 0.322 16-Aug K.K[136.11]PAAATVTK[136.11].K sp|P16403|H12_HUMAN 1 901.5568 0.44 109171 2417 2 901.551043 451.7857 Histone H1.2 OS=Homo sapiens OX=9606 GN=H1-2 PE=1 SV=2 10 1181.1 - 7.16E+06 - - - -6.349 - 1.645 0.265 - 147 1 2 0 -0.0057 9 0 0 0 6.32E+07 1.42E+08 - - - 2.4365 0.8976 221125_WJC_METTL3_EV_vs_WT_F08.02435.02435.2 0.132 12-Aug R.DR[166.11]YSAGK[136.11].R "sp|P17844|DDX5_HUMAN,tr|J3KTA4|J3KTA4_HUMAN,tr|A0A0G2JLI4|A0A0G2JLI4_HUMAN" 3 813.41 1.32 109178 2435 2 813.405506 407.7123 Probable ATP-dependent RNA helicase DDX5 OS=Homo sapiens OX=9606 GN=DDX5 PE=1 SV=1 8.59 1183.3 - 6.28E+06 - - - -5.5077 - 1.81 0.328 - 253.4 1 2 1 -0.0045 7 0 0 0 2.74E+08 2.07E+08 - - - 3.3422 0.9877 221125_WJC_METTL3_EV_vs_WT_F08.02439.02439.2 0.000119 16-Sep R.VTSTQQQTR[166.11].L "sp|P49023|PAXI_HUMAN,tr|A0A1B0GU60|A0A1B0GU60_HUMAN,tr|F5GZ78|F5GZ78_HUMAN,tr|A0A1B0GV30|A0A1B0GV30_HUMAN,tr|A0A1B0GTU4|A0A1B0GTU4_HUMAN" 5 1057.5392 0.85 109179 2439 2 1057.532334 529.7769 Paxillin OS=Homo sapiens OX=9606 GN=PXN PE=1 SV=3 9.72 1183.8 - 707892 - - - -6.4508 - 1.833 0.417 - 468.5 1 2 0 -0.0068 9 0 0 0 1.96E+07 2.31E+07 - - - 3.8719 0.9997 221125_WJC_METTL3_EV_vs_WT_F08.02447.02447.2 0.00259 16-Aug K.EDPDGEHAR[166.11].R "sp|P52272|HNRPM_HUMAN,tr|M0R019|M0R019_HUMAN,tr|M0R0N3|M0R0N3_HUMAN,tr|A0A087X0X3|A0A087X0X3_HUMAN,tr|M0QYQ7|M0QYQ7_HUMAN,tr|M0R2T0|M0R2T0_HUMAN" 6 1034.4293 1.88 109181 2447 2 1034.427529 518.2219 Heterogeneous nuclear ribonucleoprotein M OS=Homo sapiens OX=9606 GN=HNRNPM PE=1 SV=3 4.31 1185 - 882112 - - - -1.684 - 1.462 0.561 - 294.1 1 2 0 -0.0017 9 0 0 0 6.29E+07 3.35E+07 - - - 4.2828 0.9983 221125_WJC_METTL3_EV_vs_WT_F08.02449.02449.2 0.000119 16-Aug K.EDPDGEHAR.R "sp|P52272|HNRPM_HUMAN,tr|M0R019|M0R019_HUMAN,tr|M0R0N3|M0R0N3_HUMAN,tr|A0A087X0X3|A0A087X0X3_HUMAN,tr|M0QYQ7|M0QYQ7_HUMAN,tr|M0R2T0|M0R2T0_HUMAN" 6 1024.421 1.88 109182 2449 2 1024.416526 513.2178 Heterogeneous nuclear ribonucleoprotein M OS=Homo sapiens OX=9606 GN=HNRNPM PE=1 SV=3 4.31 1185.2 - 1.37E+06 - - - -4.3683 - 1.694 0.542 - 292.4 1 2 0 -0.0045 9 0 0 0 6.29E+07 3.35E+07 - - - 4.5677 0.9791 221125_WJC_METTL3_EV_vs_WT_F08.02453.02453.2 0.146 16-Jul R.VTSTQQQTR.L "sp|P49023|PAXI_HUMAN,tr|A0A1B0GU60|A0A1B0GU60_HUMAN,tr|F5GZ78|F5GZ78_HUMAN,tr|A0A1B0GV30|A0A1B0GV30_HUMAN,tr|A0A1B0GTU4|A0A1B0GTU4_HUMAN" 5 1047.5309 0.85 109184 2453 2 1047.52653 524.7727 Paxillin OS=Homo sapiens OX=9606 GN=PXN PE=1 SV=3 9.72 1185.7 - 507123 - - - -4.1583 - 1.474 0.219 - 214 1 2 0 -0.0044 9 0 0 0 1.96E+07 2.31E+07 - - - 1.7796 0.9902 221125_WJC_METTL3_EV_vs_WT_F08.02463.02463.2 0.255 16-Sep K.ATEDAKPVK.L sp|O94864|ST65G_HUMAN 1 957.5131 1.32 109189 2463 2 957.508422 479.7638 STAGA complex 65 subunit gamma OS=Homo sapiens OX=9606 GN=SUPT7L PE=1 SV=1 6.11 1186.8 - 2.97E+06 - - - -4.8971 - 1.71 0.316 - 358.1 1 2 0 -0.0047 9 0 0 0 3.87E+07 2.93E+07 - - - 2.9256 0.9308 221125_WJC_METTL3_EV_vs_WT_F08.02464.02464.2 0.0312 16-Jul K.ATEDAK[136.11]PVK[136.11].L sp|O94864|ST65G_HUMAN 1 973.5415 1.3 109190 2464 2 973.536589 487.778 STAGA complex 65 subunit gamma OS=Homo sapiens OX=9606 GN=SUPT7L PE=1 SV=1 6.11 1186.9 - 2.37E+06 - - - -5.0558 - 1.67 0.108 - 228.7 1 2 0 -0.0049 9 0 0 0 3.80E+07 2.93E+07 - - - 1.3208 0.9951 221125_WJC_METTL3_EV_vs_WT_F08.02476.02476.2 0.0505 16-Nov K.TDSSPNQAR[166.11].A "sp|P26599|PTBP1_HUMAN,tr|A0A6Q8PEX4|A0A6Q8PEX4_HUMAN,tr|A6NLN1|A6NLN1_HUMAN,tr|A0A087WU68|A0A087WU68_HUMAN,tr|K7ES59|K7ES59_HUMAN,tr|A0A7I2V4H6|A0A7I2V4H6_HUMAN,tr|A0A7I2V621|A0A7I2V621_HUMAN" 7 984.45 1.07 109200 2476 2 984.445208 493.2323 Polypyrimidine tract-binding protein 1 OS=Homo sapiens OX=9606 GN=PTBP1 PE=1 SV=1 5.5 1188.1 - 521640 - - - -4.8748 - 2.102 0.334 - 615.9 1 2 0 -0.0048 9 0 0 0 2.27E+07 2.12E+07 - - - 3.6556 0.9086 221125_WJC_METTL3_EV_vs_WT_F08.02484.02484.2 0.172 12-Jul R.K[136.11]QGAQFK[136.11].E "sp|P52948|NUP98_HUMAN,tr|A0A3B3ITD8|A0A3B3ITD8_HUMAN" 2 821.473 2.05 109206 2484 2 821.469157 411.7438 Nuclear pore complex protein Nup98-Nup96 OS=Homo sapiens OX=9606 GN=NUP98 PE=1 SV=4 10 1189.1 - 1.30E+06 - - - -4.7232 - 1.574 0.062 - 153.4 1 2 0 -0.0039 7 0 0 0 1.32E+08 6.42E+07 - - - 0.935 0.9289 221125_WJC_METTL3_EV_vs_WT_F08.02485.02485.2 1.52 16-Apr R.MC[160.03]GASEDRK.L "sp|Q6W2J9|BCOR_HUMAN,tr|H7BZ37|H7BZ37_HUMAN,tr|H7C2V9|H7C2V9_HUMAN,tr|A0A5F9ZGX7|A0A5F9ZGX7_HUMAN,tr|H7BYY2|H7BYY2_HUMAN,tr|H7C231|H7C231_HUMAN" 6 1052.4379 19.48 109207 2485 2 1052.438477 527.2262 BCL-6 corepressor OS=Homo sapiens OX=9606 GN=BCOR PE=1 SV=1 5.82 1189.2 - 772414 - - - 0.5349 - 0.85 0.14 - 58.9 3 2 0 0.0006 9 0 0 0 1.68E+07 8.62E+05 - - - -0.6084 0.9927 221125_WJC_METTL3_EV_vs_WT_F08.02489.02489.2 0.0088 16-Aug K.NGNEEGEER[166.11].M "sp|Q15155|NOMO1_HUMAN,sp|Q5JPE7|NOMO2_HUMAN,sp|P69849|NOMO3_HUMAN,tr|A0A7I2V3P4|A0A7I2V3P4_HUMAN,tr|A0A7I2V6B0|A0A7I2V6B0_HUMAN,tr|A0A7I2V4D7|A0A7I2V4D7_HUMAN,tr|A0A7I2V4T6|A0A7I2V4T6_HUMAN,tr|A0A0G2JP90|A0A0G2JP90_HUMAN,tr|A0A087X117|A0A087X117_HUMAN,tr|A0A0G2JN29|A0A0G2JN29_HUMAN,tr|A0A7I2V2Z5|A0A7I2V2Z5_HUMAN,tr|A0A087WW46|A0A087WW46_HUMAN,tr|J3KN36|J3KN36_HUMAN" 13 1042.4191 27.65 109211 2489 2 1042.413194 522.2168 Nodal modulator 1 OS=Homo sapiens OX=9606 GN=NOMO1 PE=1 SV=5 4.09 1189.7 - 223283 - - - -5.6666 - 1.426 0.513 - 274.9 1 2 0 -0.0059 9 0 0 0 3.46E+07 1.25E+06 - - - 3.8548 0.9964 221125_WJC_METTL3_EV_vs_WT_F08.02493.02493.2 0.00174 16-Oct K.TDSSPNQAR.A "sp|P26599|PTBP1_HUMAN,tr|A0A6Q8PEX4|A0A6Q8PEX4_HUMAN,tr|A6NLN1|A6NLN1_HUMAN,tr|A0A087WU68|A0A087WU68_HUMAN,tr|K7ES59|K7ES59_HUMAN,tr|A0A7I2V4H6|A0A7I2V4H6_HUMAN,tr|A0A7I2V621|A0A7I2V621_HUMAN" 7 974.4417 1.14 109213 2493 2 974.43831 488.2281 Polypyrimidine tract-binding protein 1 OS=Homo sapiens OX=9606 GN=PTBP1 PE=1 SV=1 5.5 1190.2 - 2.72E+06 - - - -3.5169 - 1.95 0.264 - 466.9 1 2 0 -0.0034 9 0 0 0 2.63E+09 2.31E+09 - - - 2.9219 0.9946 221125_WJC_METTL3_EV_vs_WT_F08.02494.02494.2 0.0623 14-Sep R.KLESTESR.S "sp|P02545|LMNA_HUMAN,tr|A0A804HL68|A0A804HL68_HUMAN,tr|Q5TCI8|Q5TCI8_HUMAN,tr|A0A6Q8PFJ0|A0A6Q8PFJ0_HUMAN,tr|A0A6Q8PHQ9|A0A6Q8PHQ9_HUMAN,tr|Q3BDU5|Q3BDU5_HUMAN" 6 948.4876 2.41 109214 2494 2 948.484114 475.2511 Prelamin-A\C OS=Homo sapiens OX=9606 GN=LMNA PE=1 SV=1 6.14 1190.3 - 1.48E+06 - - - -3.7006 - 1.759 0.26 - 339 1 2 0 -0.0035 8 0 0 0 3.66E+07 1.52E+07 - - - 2.6635 0.9971 221125_WJC_METTL3_EV_vs_WT_F08.02495.02495.2 0.00109 18-Nov R.R[166.11]LESSGAGGR[166.11].R sp|Q15773|MLF2_HUMAN 1 1008.5215 0.93 109215 2495 2 1008.516978 505.268 Myeloid leukemia factor 2 OS=Homo sapiens OX=9606 GN=MLF2 PE=1 SV=1 9.6 1190.4 - 1.31E+06 - - - -4.5294 - 2.269 0.362 - 151.6 1 2 0 -0.0046 10 0 0 0 3.74E+07 4.04E+07 - - - 4.0003 0.9989 221125_WJC_METTL3_EV_vs_WT_F08.02497.02497.2 0.00702 14-Oct R.K[136.11]LESTESR[166.11].S "sp|P02545|LMNA_HUMAN,tr|A0A804HL68|A0A804HL68_HUMAN,tr|Q5TCI8|Q5TCI8_HUMAN,tr|A0A6Q8PFJ0|A0A6Q8PFJ0_HUMAN,tr|A0A6Q8PHQ9|A0A6Q8PHQ9_HUMAN,tr|Q3BDU5|Q3BDU5_HUMAN" 6 966.5101 2.41 109217 2497 2 966.507307 484.2623 Prelamin-A\C OS=Homo sapiens OX=9606 GN=LMNA PE=1 SV=1 6.14 1190.6 - 1.00E+06 - - - -2.8836 - 2.108 0.335 - 427 1 2 0 -0.0028 8 0 0 0 3.66E+07 1.52E+07 - - - 3.7636 0.9916 221125_WJC_METTL3_EV_vs_WT_F08.02502.02502.2 0.0364 12-Aug K.KVDVTSK.A "sp|Q99961|SH3G1_HUMAN,tr|M0R0I3|M0R0I3_HUMAN,tr|M0QYE0|M0QYE0_HUMAN,tr|M0R2K6|M0R2K6_HUMAN" 4 775.444 1.39 109220 2502 2 775.440364 388.7293 Endophilin-A2 OS=Homo sapiens OX=9606 GN=SH3GL1 PE=1 SV=1 8.59 1191.2 - 1.25E+06 - - - -4.6489 - 1.729 0.288 - 234 1 2 0 -0.0036 7 0 0 0 2.54E+08 1.83E+08 - - - 2.902 0.9864 221125_WJC_METTL3_EV_vs_WT_F08.02507.02507.2 0.11 12-Sep K.K[136.11]VDVTSK[136.11].A "sp|Q99961|SH3G1_HUMAN,tr|M0R0I3|M0R0I3_HUMAN,tr|M0QYE0|M0QYE0_HUMAN,tr|M0R2K6|M0R2K6_HUMAN" 4 791.4724 1.39 109223 2507 2 791.46901 396.7435 Endophilin-A2 OS=Homo sapiens OX=9606 GN=SH3GL1 PE=1 SV=1 8.59 1191.8 - 2.51E+06 - - - -4.244 - 1.756 0.184 - 308.8 1 2 0 -0.0034 7 0 0 0 2.54E+08 1.83E+08 - - - 2.183 0.9253 221125_WJC_METTL3_EV_vs_WT_F08.02509.02509.2 0.000673 20-Oct N.AAGQAGNEAGR.F "sp|Q6UWP8|SBSN_HUMAN,sp|Q6UWP8|SBSN_HUMAN,sp|Q6UWP8|SBSN_HUMAN" 3 1000.4686 14.91 109225 2509 2 1000.464553 501.2416 Suprabasin OS=Homo sapiens OX=9606 GN=SBSN PE=1 SV=2 6.05 1192.1 - 523161 - - - -4.0651 - 2.316 0.45 - 415.9 1 1 0 -0.0041 11 0 0 0 1.72E+08 1.15E+07 - - - 4.6354 0.9869 221125_WJC_METTL3_EV_vs_WT_F08.02513.02513.2 0.000728 14-Jul K.STMGK[136.11]PQR[166.11].L sp|P62906|RL10A_HUMAN 1 921.4821 2.03 109227 2513 2 921.477255 461.7483 60S ribosomal protein L10a OS=Homo sapiens OX=9606 GN=RPL10A PE=1 SV=2 11 1192.5 - 1.93E+06 - - - -5.2643 - 1.493 0.357 - 281.4 1 2 0 -0.0049 8 0 0 0 1.36E+08 6.68E+07 - - - 2.885 0.9979 221125_WJC_METTL3_EV_vs_WT_F08.02516.02516.2 7.92E-05 14-Oct R.HGNEDTIK.E sp|Q9HCS7|SYF1_HUMAN 1 912.4301 1.36 109230 2516 2 912.426437 457.2223 Pre-mRNA-splicing factor SYF1 OS=Homo sapiens OX=9606 GN=XAB2 PE=1 SV=2 5.32 1192.9 - 871334 - - - -4.0255 - 1.669 0.459 - 368.2 1 2 0 -0.0037 8 0 0 0 5.38E+07 3.97E+07 - - - 3.9749 0.9883 221125_WJC_METTL3_EV_vs_WT_F08.02517.02517.2 6.26E-06 24-Aug K.SSSSGSVGESSSK.G "sp|P13645|K1C10_HUMAN,tr|A0A1B0GVI3|A0A1B0GVI3_HUMAN" 2 1184.5157 999 109231 2517 2 1184.509559 593.2651 "Keratin, type I cytoskeletal 10 OS=Homo sapiens OX=9606 GN=KRT10 PE=1 SV=6" 5.72 1193 - 202657 - - - -5.176 - 1.719 0.34 - 179.1 1 2 0 -0.0061 13 0 0 0 2.11E+06 0.00E+00 - - - 2.9407 0.9931 221125_WJC_METTL3_EV_vs_WT_F08.02520.02520.2 0.263 12-Sep R.KQGAQFK.E "sp|P52948|NUP98_HUMAN,tr|A0A3B3ITD8|A0A3B3ITD8_HUMAN" 2 805.4446 2.01 109232 2520 2 805.440746 403.7296 Nuclear pore complex protein Nup98-Nup96 OS=Homo sapiens OX=9606 GN=NUP98 PE=1 SV=4 10 1193.4 - 7.58E+06 - - - -4.8309 - 1.948 0.283 - 280.1 1 2 0 -0.0039 7 0 0 0 1.29E+08 6.42E+07 - - - 3.2428 0.9948 221125_WJC_METTL3_EV_vs_WT_F08.02523.02523.2 0.00387 16-Aug K.GQSEEPAGK[136.11].T "sp|A0A1B0GTU1|ZC11B_HUMAN,sp|O75152|ZC11A_HUMAN,tr|E9PBY7|E9PBY7_HUMAN,tr|A0A494C0C4|A0A494C0C4_HUMAN,tr|E9PQ61|E9PQ61_HUMAN" 5 909.4283 3.3 109235 2523 2 909.42421 455.7214 Zinc finger CCCH domain-containing protein 11B OS=Homo sapiens OX=9606 GN=ZC3H11B PE=4 SV=1 4.53 1193.6 - 1.37E+06 - - - -4.5248 - 1.655 0.379 - 308.2 1 2 0 -0.0041 9 0 0 0 6.90E+07 2.09E+07 - - - 3.2965 0.9162 221125_WJC_METTL3_EV_vs_WT_F08.02524.02524.2 0.0415 12-Aug K.SHISPSR.E sp|Q5D862|FILA2_HUMAN 1 782.4035 0.48 109236 2524 2 782.400409 392.209 Filaggrin-2 OS=Homo sapiens OX=9606 GN=FLG2 PE=1 SV=1 9.49 1193.7 - 1.11E+06 - - - -3.9519 - 1.581 0.017 - 368.2 1 2 0 -0.0031 7 0 0 0 5.08E+07 1.06E+08 - - - 0.617 0.993 221125_WJC_METTL3_EV_vs_WT_F08.02526.02526.2 0.0719 14-Aug R.QEQEEEGR[166.11].K "sp|O00154|BACH_HUMAN,tr|K7EKP8|K7EKP8_HUMAN" 2 1013.4289 1.12 109238 2526 2 1013.42386 507.7217 Cytosolic acyl coenzyme A thioester hydrolase OS=Homo sapiens OX=9606 GN=ACOT7 PE=1 SV=3 4.09 1193.9 - 217749 - - - -5.0097 - 1.589 0.396 - 287.4 1 2 0 -0.0051 8 0 0 0 2.50E+07 2.23E+07 - - - 3.361 0.8931 221125_WJC_METTL3_EV_vs_WT_F08.02529.02529.2 4.37 12-Jun R.K[136.11]FGQGSR[166.11].S "sp|P62273|RS29_HUMAN,tr|A0A2R8Y6P7|A0A2R8Y6P7_HUMAN,tr|A0A2R8Y851|A0A2R8Y851_HUMAN" 3 796.4311 1 109239 2529 2 796.427427 399.2228 40S ribosomal protein S29 OS=Homo sapiens OX=9606 GN=RPS29 PE=1 SV=2 11 1194.3 - 2.86E+07 - - - -4.5566 - 1.246 0.135 - 130 1 2 0 -0.0036 7 0 0 0 1.27E+10 1.26E+10 - - - 0.7339 0.973 221125_WJC_METTL3_EV_vs_WT_F08.02531.02531.2 0.0345 16-Jul R.HVADGEDHA.- "sp|P11117|PPAL_HUMAN,tr|B7Z7D2|B7Z7D2_HUMAN,tr|E9PHY0|E9PHY0_HUMAN,tr|A0A5F9ZHR7|A0A5F9ZHR7_HUMAN,tr|E9PQY3|E9PQY3_HUMAN" 5 949.389 - 109241 2531 2 949.385814 475.7018 Lysosomal acid phosphatase OS=Homo sapiens OX=9606 GN=ACP2 PE=1 SV=3 4.52 1194.4 - 1.16E+06 - - - -3.3274 - 1.014 0.277 - 110.7 1 2 0 -0.0032 9 0 0 0 - - - - - 1.1262 0.9872 221125_WJC_METTL3_EV_vs_WT_F08.02539.02539.2 0.0077 14-Sep R.HGNEDTIK[136.11].E sp|Q9HCS7|SYF1_HUMAN 1 920.4443 1.38 109247 2539 2 920.44012 461.2294 Pre-mRNA-splicing factor SYF1 OS=Homo sapiens OX=9606 GN=XAB2 PE=1 SV=2 5.32 1195.3 - 2.63E+06 - - - -4.5521 - 1.28 0.359 - 215.1 1 2 0 -0.0042 8 0 0 0 5.35E+07 3.86E+07 - - - 2.4358 0.7845 221125_WJC_METTL3_EV_vs_WT_F08.02543.02543.2 0.122 14-Jul K.LRTEQNER.Q "sp|Q86UP2|KTN1_HUMAN,tr|B7Z6P3|B7Z6P3_HUMAN,tr|H0YJP2|H0YJP2_HUMAN,tr|G3V4Y7|G3V4Y7_HUMAN" 4 1044.5312 1.86 109249 2543 2 1044.525567 523.2729 Kinectin OS=Homo sapiens OX=9606 GN=KTN1 PE=1 SV=1 6.14 1195.8 - 1.04E+06 - - - -5.413 - 1.686 0.244 - 98.3 1 2 1 -0.0057 8 0 0 0 2.37E+07 1.27E+07 - - - 2.4168 0.9898 221125_WJC_METTL3_EV_vs_WT_F08.02564.02564.2 0.00526 16-Oct R.ADEVAPAKK.A sp|P53396|ACLY_HUMAN 1 927.5025 2.41 109257 2564 2 927.49694 464.7585 ATP-citrate synthase OS=Homo sapiens OX=9606 GN=ACLY PE=1 SV=3 6.11 1198.6 - 1.59E+06 - - - -6.0442 - 1.909 0.385 - 565.1 1 2 0 -0.0056 9 0 0 0 3.74E+07 1.55E+07 - - - 3.7534 0.9917 221125_WJC_METTL3_EV_vs_WT_F08.02570.02570.2 0.00211 16-Sep R.ATVNSQEQK[136.11].R "sp|P46734|MP2K3_HUMAN,sp|P52564|MP2K6_HUMAN,tr|K7EIW3|K7EIW3_HUMAN,tr|E9PRZ0|E9PRZ0_HUMAN,tr|J3QR49|J3QR49_HUMAN,tr|K7ELM6|K7ELM6_HUMAN" 6 1011.5076 1.4 109259 2570 2 1011.502714 506.7611 Dual specificity mitogen-activated protein kinase kinase 3 OS=Homo sapiens OX=9606 GN=MAP2K3 PE=1 SV=2 6.05 1199.4 - 924160 - - - -4.868 - 1.736 0.33 - 283.2 1 2 0 -0.0049 9 0 0 0 2.76E+07 1.96E+07 - - - 3.0726 0.9279 221125_WJC_METTL3_EV_vs_WT_F08.02574.02574.2 1.02 14-Jul K.K[136.11]VISSANR[166.11].A "sp|P62917|RL8_HUMAN,tr|G3V1A1|G3V1A1_HUMAN,tr|E9PKZ0|E9PKZ0_HUMAN,tr|E9PP36|E9PP36_HUMAN" 4 891.5257 1.18 109261 2574 2 891.522192 446.7701 60S ribosomal protein L8 OS=Homo sapiens OX=9606 GN=RPL8 PE=1 SV=2 11 1199.8 - 3.10E+06 - - - -3.918 - 1.375 0.096 - 148.3 1 2 0 -0.0035 8 0 0 0 5.32E+07 4.51E+07 - - - 0.7094 0.9556 221125_WJC_METTL3_EV_vs_WT_F08.02576.02576.2 0.105 16-Aug R.ADEVAPAK[136.11]K[136.11].A sp|P53396|ACLY_HUMAN 1 943.5309 2.41 109262 2576 2 943.524835 472.7727 ATP-citrate synthase OS=Homo sapiens OX=9606 GN=ACLY PE=1 SV=3 6.11 1200 - 1.07E+06 - - - -6.4767 - 1.855 0.227 - 307.4 1 2 0 -0.0061 9 0 0 0 3.74E+07 1.55E+07 - - - 2.5033 0.9846 221125_WJC_METTL3_EV_vs_WT_F08.02578.02578.2 0.0101 14-Oct K.KVISSANR.A "sp|P62917|RL8_HUMAN,tr|G3V1A1|G3V1A1_HUMAN,tr|E9PKZ0|E9PKZ0_HUMAN,tr|E9PP36|E9PP36_HUMAN" 4 873.5032 1.18 109263 2578 2 873.498453 437.7589 60S ribosomal protein L8 OS=Homo sapiens OX=9606 GN=RPL8 PE=1 SV=2 11 1200.2 - 2.19E+06 - - - -5.4516 - 1.957 0.243 - 424.3 1 2 0 -0.0048 8 0 0 0 5.32E+07 4.51E+07 - - - 2.8593 0.8185 221125_WJC_METTL3_EV_vs_WT_F08.02585.02585.2 0.000236 14-Aug R.ANNPEQNR[166.11].L sp|Q7KZF4|SND1_HUMAN 1 951.4398 1.03 109267 2585 2 951.433672 476.7272 Staphylococcal nuclease domain-containing protein 1 OS=Homo sapiens OX=9606 GN=SND1 PE=1 SV=1 6.05 1201.1 - 902521 - - - -6.4166 - 1.623 0.097 - 382.1 1 2 0 -0.0061 8 0 0 0 3.29E+07 3.18E+07 - - - 1.2161 0.9978 221125_WJC_METTL3_EV_vs_WT_F08.02586.02586.3 0.000997 Nov-36 K.MVEK[136.11]DQDGGR[166.11].K "sp|P39019|RS19_HUMAN,tr|A0A075B6E2|A0A075B6E2_HUMAN" 2 1151.536 0.001 109268 2586 3 1151.532347 384.8526 40S ribosomal protein S19 OS=Homo sapiens OX=9606 GN=RPS19 PE=1 SV=2 4.56 1201.2 - 874713 - - - -3.1653 - 2.004 0.404 - 177.7 1 2 1 -0.0036 10 0 0 0 0.00E+00 3.58E+08 - - - 5.0733 0.9975 221125_WJC_METTL3_EV_vs_WT_F08.02588.02588.2 0.00122 18-Aug R.GPSTENQEAK[136.11].R "sp|Q92538|GBF1_HUMAN,tr|A0A7I2V2L4|A0A7I2V2L4_HUMAN,tr|A0A7I2YQM2|A0A7I2YQM2_HUMAN,tr|A0A7I2V3Y5|A0A7I2V3Y5_HUMAN,tr|A0A669KBG8|A0A669KBG8_HUMAN,tr|A0A7I2V2L5|A0A7I2V2L5_HUMAN,tr|A0A7I2V514|A0A7I2V514_HUMAN,tr|A0A7I2YQ65|A0A7I2YQ65_HUMAN,tr|A0A669KB10|A0A669KB10_HUMAN,tr|A0A7I2V452|A0A7I2V452_HUMAN,tr|A0A7I2V4K2|A0A7I2V4K2_HUMAN,tr|A0A7I2V529|A0A7I2V529_HUMAN,tr|A0A7P0RGV0|A0A7P0RGV0_HUMAN" 13 1067.4975 1.45 109270 2588 2 1067.493507 534.756 Golgi-specific brefeldin A-resistance guanine nucleotide exchange factor 1 OS=Homo sapiens OX=9606 GN=GBF1 PE=1 SV=2 4.53 1201.5 - 568529 - - - -3.7096 - 1.521 0.439 - 200.7 1 2 0 -0.004 10 0 0 0 8.90E+06 6.13E+06 - - - 3.4528 0.9988 221125_WJC_METTL3_EV_vs_WT_F08.02592.02592.2 0.0219 18-Oct K.LQSESTNNGK[136.11].N "sp|P42285|MTREX_HUMAN,tr|H0Y8U3|H0Y8U3_HUMAN" 2 1084.524 0.86 109272 2592 2 1084.520305 543.2693 Exosome RNA helicase MTR4 OS=Homo sapiens OX=9606 GN=MTREX PE=1 SV=3 6 1202 - 2.95E+06 - - - -3.4218 - 2.102 0.411 - 278.3 1 2 0 -0.0037 10 0 0 0 2.31E+07 2.67E+07 - - - 4.1491 0.9976 221125_WJC_METTL3_EV_vs_WT_F08.02594.02594.2 2.35E-05 16-Nov K.QDDGTGPEK.L "sp|Q92945|FUBP2_HUMAN,tr|M0R0C6|M0R0C6_HUMAN,tr|A0A087WTP3|A0A087WTP3_HUMAN" 3 945.404 1.71 109274 2594 2 945.399208 473.7093 Far upstream element-binding protein 2 OS=Homo sapiens OX=9606 GN=KHSRP PE=1 SV=4 4.03 1202.1 - 1.66E+06 - - - -5.0201 - 1.94 0.522 - 481.1 1 2 0 -0.0047 9 0 0 0 1.53E+07 8.95E+06 - - - 4.8122 0.9992 221125_WJC_METTL3_EV_vs_WT_F08.02597.02597.2 0.00182 18-Sep R.GPSTENQEAK.R "sp|Q92538|GBF1_HUMAN,tr|A0A7I2V2L4|A0A7I2V2L4_HUMAN,tr|A0A7I2YQM2|A0A7I2YQM2_HUMAN,tr|A0A7I2V3Y5|A0A7I2V3Y5_HUMAN,tr|A0A669KBG8|A0A669KBG8_HUMAN,tr|A0A7I2V2L5|A0A7I2V2L5_HUMAN,tr|A0A7I2V514|A0A7I2V514_HUMAN,tr|A0A7I2YQ65|A0A7I2YQ65_HUMAN,tr|A0A669KB10|A0A669KB10_HUMAN,tr|A0A7I2V452|A0A7I2V452_HUMAN,tr|A0A7I2V4K2|A0A7I2V4K2_HUMAN,tr|A0A7I2V529|A0A7I2V529_HUMAN,tr|A0A7P0RGV0|A0A7P0RGV0_HUMAN" 13 1059.4833 1.45 109277 2597 2 1059.481473 530.7489 Golgi-specific brefeldin A-resistance guanine nucleotide exchange factor 1 OS=Homo sapiens OX=9606 GN=GBF1 PE=1 SV=2 4.53 1202.5 - 510360 - - - -1.6933 - 1.546 0.395 - 256.3 1 2 0 -0.0018 10 0 0 0 8.90E+06 6.13E+06 - - - 3.174 0.9964 221125_WJC_METTL3_EV_vs_WT_F08.02601.02601.2 0.0146 18-Sep K.LQSESTNNGK.N "sp|P42285|MTREX_HUMAN,tr|H0Y8U3|H0Y8U3_HUMAN" 2 1076.5098 0.86 109279 2601 2 1076.505602 539.2622 Exosome RNA helicase MTR4 OS=Homo sapiens OX=9606 GN=MTREX PE=1 SV=3 6 1203.1 - 2.69E+06 - - - -3.9145 - 1.903 0.323 - 211 1 2 0 -0.0042 10 0 0 0 2.31E+07 2.67E+07 - - - 3.2214 0.9919 221125_WJC_METTL3_EV_vs_WT_F08.02602.02602.2 6.41E-06 18-Dec K.MVEK[136.11]DQDGGR[166.11].K "sp|P39019|RS19_HUMAN,tr|A0A075B6E2|A0A075B6E2_HUMAN" 2 1151.536 1.21 109280 2602 2 1151.531693 576.7753 40S ribosomal protein S19 OS=Homo sapiens OX=9606 GN=RPS19 PE=1 SV=2 4.56 1203.1 - 2.22E+06 - - - -3.7333 - 2.022 0.588 - 503 1 2 1 -0.0043 10 0 0 0 6.93E+07 5.75E+07 - - - 5.3479 0.9868 221125_WJC_METTL3_EV_vs_WT_F08.02605.02605.2 0.000121 18-Nov K.MVEKDQDGGR.K "sp|P39019|RS19_HUMAN,tr|A0A075B6E2|A0A075B6E2_HUMAN" 2 1133.5135 1.21 109283 2605 2 1133.509219 567.764 40S ribosomal protein S19 OS=Homo sapiens OX=9606 GN=RPS19 PE=1 SV=2 4.56 1203.4 - 1.70E+06 - - - -3.7962 - 1.885 0.501 - 427 1 2 1 -0.0043 10 0 0 0 6.93E+07 5.75E+07 - - - 4.5095 0.9718 221125_WJC_METTL3_EV_vs_WT_F08.02613.02613.2 0.111 12-Jul R.KLEDSTR.E sp|P15924|DESP_HUMAN 1 847.4399 4.86 109289 2613 2 847.436287 424.7272 Desmoplakin OS=Homo sapiens OX=9606 GN=DSP PE=1 SV=3 6.07 1204.2 - 3.81E+06 - - - -4.3177 - 1.404 0.205 - 223 1 2 0 -0.0037 7 0 0 0 7.85E+07 1.61E+07 - - - 1.6292 0.9978 221125_WJC_METTL3_EV_vs_WT_F08.02615.02615.2 0.00768 14-Sep K.VSDEAVKK.D "sp|O75688|PPM1B_HUMAN,tr|B8ZZF0|B8ZZF0_HUMAN,tr|A0A3B3IS24|A0A3B3IS24_HUMAN,tr|C9JIR6|C9JIR6_HUMAN" 4 874.476 2.97 109291 2615 2 874.472546 438.2453 Protein phosphatase 1B OS=Homo sapiens OX=9606 GN=PPM1B PE=1 SV=1 6.04 1204.3 - 3.68E+06 - - - -3.9464 - 1.836 0.396 - 208.9 1 2 0 -0.0035 8 0 0 0 7.79E+08 2.63E+08 - - - 3.7972 0.9992 221125_WJC_METTL3_EV_vs_WT_F08.02618.02618.2 0.000396 14-Sep R.FAQQHQAR[166.11].Q "sp|P49821|NDUV1_HUMAN,tr|G3V0I5|G3V0I5_HUMAN,tr|B4DE93|B4DE93_HUMAN" 3 994.4972 1.02 109294 2618 2 994.494647 498.2559 "NADH dehydrogenase [ubiquinone] flavoprotein 1, mitochondrial OS=Homo sapiens OX=9606 GN=NDUFV1 PE=1 SV=4" 9.76 1204.6 - 531198 - - - -2.5993 - 1.803 0.409 - 321.9 1 2 0 -0.0026 8 0 0 0 7.21E+06 7.05E+06 - - - 3.8388 0.9977 221125_WJC_METTL3_EV_vs_WT_F08.02619.02619.2 0.0438 18-Aug K.AQGETEESEK.L "sp|Q15648|MED1_HUMAN,tr|J3QKZ7|J3QKZ7_HUMAN,tr|J3KSD7|J3KSD7_HUMAN" 3 1106.4728 1.69 109295 2619 2 1106.468706 554.2437 Mediator of RNA polymerase II transcription subunit 1 OS=Homo sapiens OX=9606 GN=MED1 PE=1 SV=4 4.09 1204.8 - 353149 - - - -3.6657 - 1.704 0.405 - 255.2 1 2 0 -0.0041 10 0 0 0 4.98E+06 2.94E+06 - - - 3.5188 0.9879 221125_WJC_METTL3_EV_vs_WT_F08.02622.02622.2 0.00736 14-Jul K.TTIESHTK.S "sp|P35658|NU214_HUMAN,tr|A0A0A0MSW3|A0A0A0MSW3_HUMAN,tr|A0A494C1F2|A0A494C1F2_HUMAN" 3 915.4662 1.85 109296 2622 2 915.462059 458.7404 Nuclear pore complex protein Nup214 OS=Homo sapiens OX=9606 GN=NUP214 PE=1 SV=2 6.41 1205.2 - 1.08E+07 - - - -4.4808 - 1.466 0.304 - 235.1 1 2 0 -0.0041 8 0 0 0 2.19E+08 1.19E+08 - - - 2.4388 0.9981 221125_WJC_METTL3_EV_vs_WT_F08.02624.02624.2 0.000577 14-Oct K.VSDEAVK[136.11]K[136.11].D "sp|O75688|PPM1B_HUMAN,tr|B8ZZF0|B8ZZF0_HUMAN,tr|A0A3B3IS24|A0A3B3IS24_HUMAN,tr|C9JIR6|C9JIR6_HUMAN" 4 890.5044 2.97 109298 2624 2 890.500796 446.2595 Protein phosphatase 1B OS=Homo sapiens OX=9606 GN=PPM1B PE=1 SV=1 6.04 1205.2 - 5.66E+06 - - - -4.0438 - 2.017 0.395 - 256.1 1 2 0 -0.0036 8 0 0 0 7.79E+08 2.63E+08 - - - 4.0734 0.9857 221125_WJC_METTL3_EV_vs_WT_F08.02626.02626.2 0.0508 18-May K.AQGETEESEK[136.11].L "sp|Q15648|MED1_HUMAN,tr|J3QKZ7|J3QKZ7_HUMAN,tr|J3KSD7|J3KSD7_HUMAN" 3 1114.487 1.56 109300 2626 2 1114.483051 558.2508 Mediator of RNA polymerase II transcription subunit 1 OS=Homo sapiens OX=9606 GN=MED1 PE=1 SV=4 4.09 1205.5 - 241607 - - - -3.5092 - 1.064 0.338 - 71.2 1 2 0 -0.0039 10 0 0 0 4.60E+06 2.94E+06 - - - 1.7094 0.9986 221125_WJC_METTL3_EV_vs_WT_F08.02632.02632.2 0.00172 14-Sep R.FAQQHQAR.Q "sp|P49821|NDUV1_HUMAN,tr|G3V0I5|G3V0I5_HUMAN,tr|B4DE93|B4DE93_HUMAN" 3 984.489 0.74 109304 2632 2 984.4856 493.2518 "NADH dehydrogenase [ubiquinone] flavoprotein 1, mitochondrial OS=Homo sapiens OX=9606 GN=NDUFV1 PE=1 SV=4" 9.76 1206.3 - 706806 - - - -3.415 - 1.81 0.417 - 387.5 1 2 0 -0.0034 8 0 0 0 7.50E+06 1.01E+07 - - - 3.9094 0.9992 221125_WJC_METTL3_EV_vs_WT_F08.02633.02633.2 0.000153 20-Oct K.VTPQSDGSSSK[136.11].V "sp|P34932|HSP74_HUMAN,tr|A0A087WYC1|A0A087WYC1_HUMAN" 2 1099.5237 0.1 109305 2633 2 1099.519887 550.7691 Heat shock 70 kDa protein 4 OS=Homo sapiens OX=9606 GN=HSPA4 PE=1 SV=4 5.81 1206.4 - 524711 - - - -3.4515 - 1.893 0.541 - 312.9 1 2 0 -0.0038 11 0 0 0 4.26E+07 4.26E+08 - - - 4.762 0.8004 221125_WJC_METTL3_EV_vs_WT_F08.02647.02647.2 0.156 16-Dec K.LR[166.11]EQGTESR[166.11].S "sp|P42166|LAP2A_HUMAN,sp|P42167|LAP2B_HUMAN,tr|G5E972|G5E972_HUMAN,tr|H0YJH7|H0YJH7_HUMAN" 4 1094.5583 1.17 109313 2647 2 1094.552975 548.2864 "Lamina-associated polypeptide 2, isoform alpha OS=Homo sapiens OX=9606 GN=TMPO PE=1 SV=2" 6.14 1208.2 - 1.32E+06 - - - -4.8878 - 1.821 0.19 - 284.3 1 2 1 -0.0054 9 0 0 0 1.75E+07 1.50E+07 - - - 2.1767 0.9264 221125_WJC_METTL3_EV_vs_WT_F08.02649.02649.2 0.0633 16-Nov K.LREQGTESR.S "sp|P42166|LAP2A_HUMAN,sp|P42167|LAP2B_HUMAN,tr|G5E972|G5E972_HUMAN,tr|H0YJH7|H0YJH7_HUMAN" 4 1074.5418 1.19 109315 2649 2 1074.536428 538.2782 "Lamina-associated polypeptide 2, isoform alpha OS=Homo sapiens OX=9606 GN=TMPO PE=1 SV=2" 6.14 1208.4 - 1.01E+06 - - - -4.9854 - 2.058 0.299 - 208.7 1 2 1 -0.0054 9 0 0 0 1.78E+07 1.50E+07 - - - 3.3357 0.9214 221125_WJC_METTL3_EV_vs_WT_F08.02655.02655.2 1.99 12-Jul K.DISENK[136.11]R[166.11].A "sp|P11142|HSP7C_HUMAN,sp|Q13029|PRDM2_HUMAN,tr|E9PNE6|E9PNE6_HUMAN,tr|A8K7Q2|A8K7Q2_HUMAN,tr|E9PKE3|E9PKE3_HUMAN,tr|E9PN89|E9PN89_HUMAN" 6 878.4577 0.15 109319 2655 2 878.452667 440.2361 Heat shock cognate 71 kDa protein OS=Homo sapiens OX=9606 GN=HSPA8 PE=1 SV=1 6.07 1209.1 - 6.25E+07 - - - -5.6895 - 1.498 0.167 - 153.3 1 2 0 -0.005 7 0 0 0 2.31E+09 1.51E+10 - - - 1.5534 0.8941 221125_WJC_METTL3_EV_vs_WT_F08.02657.02657.2 0.365 12-Aug K.SK[136.11]DIVNK[136.11].M "sp|P52732|KIF11_HUMAN,tr|A0A7I2V3A9|A0A7I2V3A9_HUMAN" 2 818.4833 4.29 109321 2657 2 818.480079 410.2489 Kinesin-like protein KIF11 OS=Homo sapiens OX=9606 GN=KIF11 PE=1 SV=2 8.31 1209.2 - 6.26E+06 - - - -3.8962 - 1.735 0.191 - 207.3 1 2 1 -0.0032 7 0 0 0 1.97E+09 4.59E+08 - - - 2.1966 0.998 221125_WJC_METTL3_EV_vs_WT_F08.02659.02659.2 2.66E-05 20-Oct K.VTPQSDGSSSK.V "sp|P34932|HSP74_HUMAN,tr|A0A087WYC1|A0A087WYC1_HUMAN" 2 1091.5095 0.1 109323 2659 2 1091.505206 546.762 Heat shock 70 kDa protein 4 OS=Homo sapiens OX=9606 GN=HSPA4 PE=1 SV=4 5.81 1209.3 - 1.61E+06 - - - -3.9175 - 1.735 0.456 - 231.3 1 2 0 -0.0043 11 0 0 0 4.26E+07 4.26E+08 - - - 3.8983 0.7774 221125_WJC_METTL3_EV_vs_WT_F08.02663.02663.2 8.8 12-Jul K.DISENKR.A "sp|P11142|HSP7C_HUMAN,sp|Q13029|PRDM2_HUMAN,tr|E9PNE6|E9PNE6_HUMAN,tr|A8K7Q2|A8K7Q2_HUMAN,tr|E9PKE3|E9PKE3_HUMAN,tr|E9PN89|E9PN89_HUMAN" 6 860.4352 0.15 109325 2663 2 860.431887 431.2249 Heat shock cognate 71 kDa protein OS=Homo sapiens OX=9606 GN=HSPA8 PE=1 SV=1 6.07 1209.8 - 1.68E+07 - - - -3.8446 - 1.176 0.037 - 155.1 1 2 0 -0.0033 7 0 0 0 2.30E+09 1.51E+10 - - - -0.1731 0.9344 221125_WJC_METTL3_EV_vs_WT_F08.02664.02664.2 0.218 14-Jul K.GNENGHFK.L sp|Q14574|DSC3_HUMAN 1 901.4042 3.53 109326 2664 2 901.39893 451.7094 Desmocollin-3 OS=Homo sapiens OX=9606 GN=DSC3 PE=1 SV=3 6.75 1209.9 - 4.41E+06 - - - -5.8786 - 1.105 0.334 - 106.2 1 2 0 -0.0053 8 0 0 0 5.71E+07 1.62E+07 - - - 1.8074 0.9975 221125_WJC_METTL3_EV_vs_WT_F08.02707.02707.2 7.82E-06 18-Oct K.EAASGTTPQK.S "sp|Q13428|TCOF_HUMAN,tr|E7ETY2|E7ETY2_HUMAN,tr|A0A3B3IS06|A0A3B3IS06_HUMAN,tr|A0A6I8PRA0|A0A6I8PRA0_HUMAN" 4 988.4825 0.13 109348 2707 2 988.477918 495.2485 Treacle protein OS=Homo sapiens OX=9606 GN=TCOF1 PE=1 SV=3 6.1 1215 - 860913 - - - -4.6748 - 1.989 0.457 - 438.6 1 2 0 -0.0046 10 0 0 0 3.23E+07 2.56E+08 - - - 4.3343 0.9899 221125_WJC_METTL3_EV_vs_WT_F08.02708.02708.2 0.00261 14-Aug K.YVDEASKK.E "sp|P62249|RS16_HUMAN,tr|M0R210|M0R210_HUMAN" 2 938.4709 1.07 109349 2708 2 938.467024 470.2427 40S ribosomal protein S16 OS=Homo sapiens OX=9606 GN=RPS16 PE=1 SV=2 6.07 1215.1 - 2.67E+06 - - - -4.1429 - 1.42 0.31 - 170.1 1 2 0 -0.0039 8 0 0 0 1.03E+08 9.58E+07 - - - 2.387 0.8622 221125_WJC_METTL3_EV_vs_WT_F08.02709.02709.2 1.65 12-Aug K.RPNVSPK.V sp|Q9NX58|LYAR_HUMAN 1 796.4555 0.85 109350 2709 2 796.451435 399.235 Cell growth-regulating nucleolar protein OS=Homo sapiens OX=9606 GN=LYAR PE=1 SV=2 11 1215.1 - 2.14E+06 - - - -5.1491 - 1.283 0.135 - 230.5 1 2 0 -0.0041 7 0 0 0 6.46E+07 7.63E+07 - - - 0.8264 0.9986 221125_WJC_METTL3_EV_vs_WT_F08.02710.02710.2 0.00169 18-Sep K.ESSTADSEAR.S "sp|Q9H089|LSG1_HUMAN,tr|H7C2X7|H7C2X7_HUMAN" 2 1051.4418 1.03 109351 2710 2 1051.437758 526.7282 Large subunit GTPase 1 homolog OS=Homo sapiens OX=9606 GN=LSG1 PE=1 SV=2 4.14 1215.2 - 1.38E+06 - - - -3.8414 - 1.945 0.459 - 464.4 1 2 0 -0.004 10 0 0 0 2.81E+07 2.74E+07 - - - 4.2869 0.9664 221125_WJC_METTL3_EV_vs_WT_F08.02715.02715.2 0.583 12-Jul K.R[166.11]PNVSPK[136.11].V sp|Q9NX58|LYAR_HUMAN 1 814.478 0.83 109354 2715 2 814.474689 408.2463 Cell growth-regulating nucleolar protein OS=Homo sapiens OX=9606 GN=LYAR PE=1 SV=2 11 1215.8 - 3.78E+06 - - - -4.0725 - 1.445 0.156 - 254.4 1 2 0 -0.0033 7 0 0 0 6.36E+07 7.62E+07 - - - 1.3585 0.7873 221125_WJC_METTL3_EV_vs_WT_F08.02721.02721.2 0.143 12-Jul K.SKDIVNK.M "sp|P52732|KIF11_HUMAN,tr|A0A7I2V3A9|A0A7I2V3A9_HUMAN" 2 802.4549 4.28 109358 2721 2 802.451346 402.2347 Kinesin-like protein KIF11 OS=Homo sapiens OX=9606 GN=KIF11 PE=1 SV=2 8.31 1216.4 - 6.06E+06 - - - -4.389 - 1.582 0.179 - 133.7 1 2 1 -0.0035 7 0 0 0 1.97E+09 4.59E+08 - - - 1.8154 0.9825 221125_WJC_METTL3_EV_vs_WT_F08.02726.02726.2 0.00656 16-Aug K.SVTENQENK[136.11].L "sp|Q9NVC6|MED17_HUMAN,tr|A0A1W2PNF3|A0A1W2PNF3_HUMAN,tr|E9PM72|E9PM72_HUMAN,tr|A0A1W2PQ48|A0A1W2PQ48_HUMAN,tr|A0A1W2PS27|A0A1W2PS27_HUMAN,tr|A0A1W2PR99|A0A1W2PR99_HUMAN,tr|A0A1W2PRB8|A0A1W2PRB8_HUMAN,tr|E9PKQ4|E9PKQ4_HUMAN,tr|A0A1W2PPP8|A0A1W2PPP8_HUMAN,tr|A0A1W2PNW7|A0A1W2PNW7_HUMAN,tr|A0A1W2PS69|A0A1W2PS69_HUMAN,tr|A0A1W2PRX4|A0A1W2PRX4_HUMAN" 12 1055.4975 1.43 109362 2726 2 1055.491026 528.756 Mediator of RNA polymerase II transcription subunit 17 OS=Homo sapiens OX=9606 GN=MED17 PE=1 SV=2 4.53 1216.8 - 731456 - - - -6.1023 - 1.589 0.38 - 151.5 1 2 0 -0.0064 9 0 0 0 2.24E+07 1.57E+07 - - - 3.1854 0.9961 221125_WJC_METTL3_EV_vs_WT_F08.02729.02729.2 0.000296 12-Jul R.HYDDPGK.G sp|P55316|FOXG1_HUMAN 1 830.3559 0.76 109363 2729 2 830.352173 416.1852 Forkhead box protein G1 OS=Homo sapiens OX=9606 GN=FOXG1 PE=1 SV=2 5.21 1217.2 - 1.70E+06 - - - -4.4668 - 1.344 0.488 - 278 1 2 0 -0.0037 7 0 0 0 3.17E+07 4.16E+07 - - - 3.581 0.9988 221125_WJC_METTL3_EV_vs_WT_F08.02736.02736.2 0.0501 14-Sep K.HLTSNSPR.L sp|P14923|PLAK_HUMAN 1 910.4621 34.39 109367 2736 2 910.459122 456.2383 Junction plakoglobin OS=Homo sapiens OX=9606 GN=JUP PE=1 SV=3 9.76 1218 - 2.53E+07 - - - -3.2467 - 1.617 0.462 - 251.6 1 2 0 -0.003 8 0 0 0 6.22E+08 1.81E+07 - - - 3.9018 0.9988 221125_WJC_METTL3_EV_vs_WT_F08.02739.02739.2 0.000105 16-Aug R.C[160.03]GESGHLAK[136.11].D "sp|P62633|CNBP_HUMAN,tr|D6RAT4|D6RAT4_HUMAN" 2 965.448 0.69 109370 2739 2 965.444256 483.7313 CCHC-type zinc finger nucleic acid binding protein OS=Homo sapiens OX=9606 GN=CNBP PE=1 SV=1 6.74 1218.1 - 927320 - - - -3.8935 - 2.038 0.474 - 205.6 1 2 0 -0.0038 9 0 0 0 5.03E+07 7.29E+07 - - - 4.6005 0.9349 221125_WJC_METTL3_EV_vs_WT_F08.02740.02740.2 0.154 20-Jun R.GPEQTSGQTAK[136.11].D sp|Q8NFC6|BD1L1_HUMAN 1 1110.5397 4.82 109371 2740 2 1110.539249 556.2771 Biorientation of chromosomes in cell division protein 1-like 1 OS=Homo sapiens OX=9606 GN=BOD1L1 PE=1 SV=2 6 1218.3 - 308727 - - - -0.3764 - 1.025 0.039 - 122.6 1 2 0 -0.0004 11 0 0 0 3.93E+07 8.16E+06 - - - -0.6043 0.999 221125_WJC_METTL3_EV_vs_WT_F08.02745.02745.2 0.000123 14-Jul K.YVDEASK[136.11]K[136.11].E "sp|P62249|RS16_HUMAN,tr|M0R210|M0R210_HUMAN" 2 954.4993 1.07 109374 2745 2 954.496466 478.2569 40S ribosomal protein S16 OS=Homo sapiens OX=9606 GN=RPS16 PE=1 SV=2 6.07 1218.8 - 4.18E+06 - - - -2.9817 - 1.649 0.454 - 109.4 1 2 0 -0.0028 8 0 0 0 1.03E+08 9.58E+07 - - - 3.9018 0.9991 221125_WJC_METTL3_EV_vs_WT_F08.02746.02746.2 0.00236 16-Sep K.SVTENQENK.L "sp|Q9NVC6|MED17_HUMAN,tr|A0A1W2PNF3|A0A1W2PNF3_HUMAN,tr|E9PM72|E9PM72_HUMAN,tr|A0A1W2PQ48|A0A1W2PQ48_HUMAN,tr|A0A1W2PS27|A0A1W2PS27_HUMAN,tr|A0A1W2PR99|A0A1W2PR99_HUMAN,tr|A0A1W2PRB8|A0A1W2PRB8_HUMAN,tr|E9PKQ4|E9PKQ4_HUMAN,tr|A0A1W2PPP8|A0A1W2PPP8_HUMAN,tr|A0A1W2PNW7|A0A1W2PNW7_HUMAN,tr|A0A1W2PS69|A0A1W2PS69_HUMAN,tr|A0A1W2PRX4|A0A1W2PRX4_HUMAN" 12 1047.4833 1.43 109375 2746 2 1047.480206 524.7489 Mediator of RNA polymerase II transcription subunit 17 OS=Homo sapiens OX=9606 GN=MED17 PE=1 SV=2 4.53 1218.9 - 1.43E+06 - - - -2.9222 - 1.616 0.476 - 177.5 1 2 0 -0.0031 9 0 0 0 2.24E+07 1.57E+07 - - - 3.9443 0.9994 221125_WJC_METTL3_EV_vs_WT_F08.02754.02754.2 0.0166 14-Aug R.DC[160.03]STQTER[166.11].G "sp|Q4VCS5|AMOT_HUMAN,tr|E7ERM3|E7ERM3_HUMAN" 2 1005.4061 0.72 109380 2754 2 1005.402793 503.7103 Angiomotin OS=Homo sapiens OX=9606 GN=AMOT PE=1 SV=1 4.37 1219.9 - 745150 - - - -3.2823 - 1.894 0.558 - 280.6 1 2 0 -0.0033 8 0 0 0 1.39E+07 1.92E+07 - - - 5.0876 0.996 221125_WJC_METTL3_EV_vs_WT_F08.02757.02757.2 0.00713 14-Aug K.TGIHTSTR.L sp|O43395|PRPF3_HUMAN 1 871.4512 1.71 109381 2757 2 871.448938 436.7329 U4\U6 small nuclear ribonucleoprotein Prp3 OS=Homo sapiens OX=9606 GN=PRPF3 PE=1 SV=2 9.44 1220.3 - 1.25E+06 - - - -2.5716 - 1.385 0.294 - 241.8 1 2 0 -0.0022 8 0 0 0 6.85E+07 4.00E+07 - - - 2.1941 0.9335 221125_WJC_METTL3_EV_vs_WT_F08.02759.02759.2 1.71E-05 16-Sep R.GPGASVHDR[166.11].N "sp|P46379|BAG6_HUMAN,tr|F6UR09|F6UR09_HUMAN,tr|A0A7I2V508|A0A7I2V508_HUMAN,tr|F6U1F2|F6U1F2_HUMAN,tr|F6U341|F6U341_HUMAN,tr|F6WML8|F6WML8_HUMAN,tr|A0A0G2JJM1|A0A0G2JJM1_HUMAN,tr|X6REW1|X6REW1_HUMAN,tr|A0A7I2V3H1|A0A7I2V3H1_HUMAN,tr|A0A7P0MQS5|A0A7P0MQS5_HUMAN,tr|F6XTU0|F6XTU0_HUMAN,tr|F6X9W3|F6X9W3_HUMAN,tr|F6VEM6|F6VEM6_HUMAN,tr|A0A0G2JJR8|A0A0G2JJR8_HUMAN,tr|F6S6P2|F6S6P2_HUMAN,tr|F6TC96|F6TC96_HUMAN,tr|A0A0G2JL47|A0A0G2JL47_HUMAN,tr|A0A024RCR6|A0A024RCR6_HUMAN,tr|A0A0G2JK23|A0A0G2JK23_HUMAN,tr|A0A1B0GX79|A0A1B0GX79_HUMAN" 20 904.439 1.58 109383 2759 2 905.445447 453.2268 Large proline-rich protein BAG6 OS=Homo sapiens OX=9606 GN=BAG6 PE=1 SV=2 6.74 1220.4 - 2.25E+06 - - - 1112.7328 - 1.821 0.427 - 367.1 1 2 0 1.0064 9 0 0 0 5.07E+07 3.21E+07 - - - 3.6129 0.9644 221125_WJC_METTL3_EV_vs_WT_F08.02768.02768.2 0.135 14-Jul K.FADTQKDK.E "sp|Q92879|CELF1_HUMAN,sp|O95319|CELF2_HUMAN,tr|G5EA30|G5EA30_HUMAN,tr|E9PC62|E9PC62_HUMAN,tr|A0A1B0GU44|A0A1B0GU44_HUMAN,tr|A0A0J9YX66|A0A0J9YX66_HUMAN,tr|A0A1B0GUN8|A0A1B0GUN8_HUMAN,tr|Q5VZZ6|Q5VZZ6_HUMAN,tr|A0A0J9YXJ0|A0A0J9YXJ0_HUMAN,tr|V9GYD9|V9GYD9_HUMAN" 10 951.4662 1.45 109390 2768 2 951.463907 476.7404 CUGBP Elav-like family member 1 OS=Homo sapiens OX=9606 GN=CELF1 PE=1 SV=2 5.96 1221.4 - 821383 - - - -2.369 - 1.324 0.318 - 112.6 1 2 1 -0.0023 8 0 0 0 8.78E+06 6.06E+06 - - - 2.2355 0.999 221125_WJC_METTL3_EV_vs_WT_F08.02769.02769.2 0.00865 18-Aug R.DGSGPGEEGK[136.11].Q sp|Q8IYI6|EXOC8_HUMAN 1 939.4025 1.56 109391 2769 2 939.403562 470.7085 Exocyst complex component 8 OS=Homo sapiens OX=9606 GN=EXOC8 PE=1 SV=2 4.14 1221.5 - 757633 - - - 1.1262 - 1.414 0.358 - 231.8 1 2 0 0.0011 10 0 0 0 4.07E+07 2.62E+07 - - - 2.6518 0.9954 221125_WJC_METTL3_EV_vs_WT_F08.02773.02773.2 0.298 14-Jul K.TGIHTSTR[166.11].L sp|O43395|PRPF3_HUMAN 1 881.4594 1.89 109393 2773 2 881.457608 441.737 U4\U6 small nuclear ribonucleoprotein Prp3 OS=Homo sapiens OX=9606 GN=PRPF3 PE=1 SV=2 9.44 1222 - 3.02E+06 - - - -2.0886 - 1.255 0.279 - 157.7 1 2 0 -0.0018 8 0 0 0 6.54E+07 3.46E+07 - - - 1.7861 0.9982 221125_WJC_METTL3_EV_vs_WT_F08.02775.02775.2 5.20E-05 18-Nov K.QAESASEAAK.K "sp|P51572|BAP31_HUMAN,tr|A0A2R8Y5M6|A0A2R8Y5M6_HUMAN,tr|C9J0M4|C9J0M4_HUMAN,tr|C9JQ75|C9JQ75_HUMAN,tr|C9JSP1|C9JSP1_HUMAN,tr|C9JMD7|C9JMD7_HUMAN" 6 990.4618 2.71 109395 2775 2 990.457049 496.2382 B-cell receptor-associated protein 31 OS=Homo sapiens OX=9606 GN=BCAP31 PE=1 SV=3 4.53 1222.2 - 997839 - - - -4.8008 - 2.227 0.52 - 594.4 1 2 0 -0.0048 10 0 0 0 3.24E+07 1.20E+07 - - - 5.1151 0.978 221125_WJC_METTL3_EV_vs_WT_F08.02778.02778.2 0.00226 16-Oct K.TK[136.11]EEVEAAK[136.11].A sp|Q92575|UBXN4_HUMAN 1 1019.547 0.96 109398 2778 2 1019.544658 510.7808 UBX domain-containing protein 4 OS=Homo sapiens OX=9606 GN=UBXN4 PE=1 SV=2 4.78 1222.5 - 317904 - - - -2.2873 - 1.897 0.234 - 270.3 1 2 1 -0.0023 9 0 0 0 7.44E+06 7.79E+06 - - - 2.6209 0.9993 221125_WJC_METTL3_EV_vs_WT_F08.02779.02779.2 0.00242 20-Jul R.LTGTSNNSAGK[136.11].L "sp|Q7Z401|MYCPP_HUMAN,tr|H3BTW5|H3BTW5_HUMAN,tr|A0A7I2RAZ6|A0A7I2RAZ6_HUMAN,tr|A0A0U1RR27|A0A0U1RR27_HUMAN" 4 1056.5291 2.37 109399 2779 2 1056.52746 529.2718 C-myc promoter-binding protein OS=Homo sapiens OX=9606 GN=DENND4A PE=1 SV=2 8.75 1222.6 - 248978 - - - -1.5541 - 1.71 0.368 - 121.5 1 2 0 -0.0016 11 0 0 0 4.16E+06 1.75E+06 - - - 3.2099 0.9992 221125_WJC_METTL3_EV_vs_WT_F08.02784.02784.2 0.00578 14-Aug R.QIEHC[160.03]EGR.M sp|P15924|DESP_HUMAN 1 1027.4505 58.95 109402 2784 2 1027.447694 514.7325 Desmoplakin OS=Homo sapiens OX=9606 GN=DSP PE=1 SV=3 5.4 1223.2 - 2.89E+06 - - - -2.7583 - 1.676 0.465 - 426.8 1 2 0 -0.0028 8 0 0 0 2.28E+07 3.87E+05 - - - 4.0321 0.8495 221125_WJC_METTL3_EV_vs_WT_F08.02785.02785.2 2.09 12-Sep T.K[136.11]ELEDAK[136.11].K "sp|O60610|DIAP1_HUMAN,tr|A0A2R8Y5N1|A0A2R8Y5N1_HUMAN,tr|A0A140T8Z0|A0A140T8Z0_HUMAN,tr|A0A0G2JH68|A0A0G2JH68_HUMAN,tr|H9KV28|H9KV28_HUMAN" 5 847.4622 0.71 109403 2785 2 847.4609 424.7384 Protein diaphanous homolog 1 OS=Homo sapiens OX=9606 GN=DIAPH1 PE=1 SV=2 4.68 1223.3 - 2.09E+06 - - - -1.5316 - 1.735 0.144 - 391 1 1 0 -0.0013 7 0 0 0 1.33E+07 1.87E+07 - - - 1.8501 0.9729 221125_WJC_METTL3_EV_vs_WT_F08.02789.02789.2 0.0136 16-Oct K.TKEEVEAAK.A sp|Q92575|UBXN4_HUMAN 1 1003.5186 0.96 109407 2789 2 1003.516537 502.7666 UBX domain-containing protein 4 OS=Homo sapiens OX=9606 GN=UBXN4 PE=1 SV=2 4.78 1223.8 - 558892 - - - -2.0458 - 1.864 0.194 - 244.1 1 2 1 -0.0021 9 0 0 0 7.44E+06 7.79E+06 - - - 2.2748 0.9997 221125_WJC_METTL3_EV_vs_WT_F08.02791.02791.2 3.24E-06 18-Sep R.NDDSEADTAK[136.11].L "sp|Q5UIP0|RIF1_HUMAN,tr|H7C2B5|H7C2B5_HUMAN" 2 1072.44 1.34 109409 2791 2 1072.43703 537.2273 Telomere-associated protein RIF1 OS=Homo sapiens OX=9606 GN=RIF1 PE=1 SV=2 3.84 1224 - 342168 - - - -2.7806 - 2.125 0.614 - 422.9 1 2 0 -0.003 10 0 0 0 7.37E+06 5.51E+06 - - - 5.6791 1 221125_WJC_METTL3_EV_vs_WT_F08.02797.02797.2 2.23E-05 18-Dec R.NDDSEADTAK.L "sp|Q5UIP0|RIF1_HUMAN,tr|H7C2B5|H7C2B5_HUMAN" 2 1064.4258 1.31 109413 2797 2 1064.422372 533.2202 Telomere-associated protein RIF1 OS=Homo sapiens OX=9606 GN=RIF1 PE=1 SV=2 3.84 1224.7 - 812849 - - - -3.2318 - 2.454 0.605 - 747.2 1 2 0 -0.0034 10 0 0 0 7.24E+06 5.51E+06 - - - 6.0143 0.984 221125_WJC_METTL3_EV_vs_WT_F08.02798.02798.2 0.0191 12-Jul R.K[136.11]LTAEQR[166.11].K sp|O43395|PRPF3_HUMAN 1 862.4991 4.7 109414 2798 2 862.495788 432.2568 U4\U6 small nuclear ribonucleoprotein Prp3 OS=Homo sapiens OX=9606 GN=PRPF3 PE=1 SV=2 8.75 1224.8 - 626271 - - - -3.8817 - 1.735 0.142 - 245 1 2 0 -0.0033 7 0 0 0 2.65E+07 5.65E+06 - - - 1.8347 0.9982 221125_WJC_METTL3_EV_vs_WT_F08.02800.02800.2 0.00881 16-Jul R.STEC[160.03]AQEGR.L sp|O60318|GANP_HUMAN 1 1036.4244 1.37 109416 2800 2 1036.421371 519.2195 Germinal-center associated nuclear protein OS=Homo sapiens OX=9606 GN=MCM3AP PE=1 SV=2 4.53 1225 - 493386 - - - -2.8965 - 1.556 0.387 - 209.1 1 2 0 -0.003 9 0 0 0 6.93E+06 5.06E+06 - - - 3.1775 0.9994 221125_WJC_METTL3_EV_vs_WT_F08.02802.02802.2 0.00308 16-Sep R.STEC[160.03]AQEGR[166.11].L sp|O60318|GANP_HUMAN 1 1046.4326 1.42 109418 2802 2 1046.43005 524.2236 Germinal-center associated nuclear protein OS=Homo sapiens OX=9606 GN=MCM3AP PE=1 SV=2 4.53 1225.3 - 319399 - - - -2.4779 - 1.874 0.431 - 410.8 1 2 0 -0.0026 9 0 0 0 6.69E+06 4.71E+06 - - - 4.0406 0.9933 221125_WJC_METTL3_EV_vs_WT_F08.02807.02807.2 1.07 12-Jul R.KLTAEQR.K sp|O43395|PRPF3_HUMAN 1 844.4767 6 109421 2807 2 844.474604 423.2456 U4\U6 small nuclear ribonucleoprotein Prp3 OS=Homo sapiens OX=9606 GN=PRPF3 PE=1 SV=2 8.75 1225.9 - 1.82E+06 - - - -2.4417 - 1.876 0.089 - 223.3 1 2 0 -0.0021 7 0 0 0 3.48E+07 5.81E+06 - - - 1.6912 0.7726 221125_WJC_METTL3_EV_vs_WT_F08.02808.02808.2 0.0459 14-Jul H.QALEEEK[136.11]K[136.11].K "sp|Q02108|GCYA1_HUMAN,sp|P33402|GCYA2_HUMAN,tr|J3KPQ8|J3KPQ8_HUMAN" 3 989.5364 0.35 109422 2808 2 989.532237 495.7755 Guanylate cyclase soluble subunit alpha-1 OS=Homo sapiens OX=9606 GN=GUCY1A1 PE=1 SV=2 4.79 1226.1 - 922330 - - - -4.2333 - 1.543 0.379 - 241 1 1 0 -0.0042 8 0 0 0 2.85E+06 8.22E+06 - - - 3.1471 0.999 221125_WJC_METTL3_EV_vs_WT_F08.02809.02809.2 0.00198 16-Oct R.AQQQAEAER.A sp|Q15149|PLEC_HUMAN 1 1029.4839 1.07 109423 2809 2 1029.482593 515.7492 Plectin OS=Homo sapiens OX=9606 GN=PLEC PE=1 SV=3 4.53 1226.2 - 798197 - - - -1.3045 - 1.995 0.224 - 656.9 1 2 0 -0.0013 9 0 0 0 8.25E+06 7.70E+06 - - - 2.6931 0.9692 221125_WJC_METTL3_EV_vs_WT_F08.02815.02815.2 0.174 16-Aug K.IQAQEDR[166.11]EK[136.11].G "sp|Q9Y3D7|TIM16_HUMAN,tr|I3L3T0|I3L3T0_HUMAN,tr|A0A0A6YYL4|A0A0A6YYL4_HUMAN,tr|I3L0X9|I3L0X9_HUMAN" 4 1133.5796 1.71 109429 2815 2 1133.576724 567.7971 Mitochondrial import inner membrane translocase subunit TIM16 OS=Homo sapiens OX=9606 GN=PAM16 PE=1 SV=2 4.68 1226.9 - 128521 - - - -2.5115 - 1.611 0.276 - 232.5 1 2 1 -0.0028 9 0 0 0 7.52E+06 4.40E+06 - - - 2.4582 0.9792 221125_WJC_METTL3_EV_vs_WT_F08.02818.02818.2 0.157 14-Aug K.QQQDAPGR.S sp|Q5T481|RBM20_HUMAN 1 898.4257 1.02 109430 2818 2 898.422891 450.2201 RNA-binding protein 20 OS=Homo sapiens OX=9606 GN=RBM20 PE=1 SV=3 5.84 1227.3 - 981338 - - - -3.1188 - 1.61 0.099 - 436.6 1 2 0 -0.0028 8 0 0 0 1.55E+07 1.51E+07 - - - 1.2076 0.9945 221125_WJC_METTL3_EV_vs_WT_F08.02819.02819.2 0.185 14-Aug K.QQQDAPGR[166.11].S sp|Q5T481|RBM20_HUMAN 1 908.434 1.04 109431 2819 2 908.433333 455.2243 RNA-binding protein 20 OS=Homo sapiens OX=9606 GN=RBM20 PE=1 SV=3 5.84 1227.4 - 1.29E+06 - - - -0.6935 - 1.672 0.066 - 447.2 1 2 0 -0.0006 8 0 0 0 1.54E+07 1.48E+07 - - - 1.0785 0.9706 221125_WJC_METTL3_EV_vs_WT_F08.02824.02824.2 0.00692 16-Aug K.IQAQEDREK.G "sp|Q9Y3D7|TIM16_HUMAN,tr|I3L3T0|I3L3T0_HUMAN,tr|A0A0A6YYL4|A0A0A6YYL4_HUMAN,tr|I3L0X9|I3L0X9_HUMAN" 4 1115.5571 1.71 109436 2824 2 1115.554028 558.7858 Mitochondrial import inner membrane translocase subunit TIM16 OS=Homo sapiens OX=9606 GN=PAM16 PE=1 SV=2 4.68 1227.9 - 402356 - - - -2.7547 - 1.705 0.282 - 216.7 1 2 1 -0.0031 9 0 0 0 7.52E+06 4.40E+06 - - - 2.6665 0.9538 221125_WJC_METTL3_EV_vs_WT_F08.02825.02825.2 0.0854 18-Aug E.AGGQSSQEER[166.11].L "sp|Q9P2H5|UBP35_HUMAN,tr|E9PK78|E9PK78_HUMAN" 2 1057.4664 1.91 109437 2825 2 1057.466595 529.7405 Ubiquitin carboxyl-terminal hydrolase 35 OS=Homo sapiens OX=9606 GN=USP35 PE=1 SV=3 4.53 1228.1 - 378529 - - - 0.1986 - 1.681 0.283 - 260.1 1 1 0 0.0002 10 0 0 0 9.85E+06 5.16E+06 - - - 2.5809 0.9996 221125_WJC_METTL3_EV_vs_WT_F08.02832.02832.2 0.000156 16-Sep R.NENESEAAR.R "sp|Q9UN37|VPS4A_HUMAN,tr|I3L4J1|I3L4J1_HUMAN" 2 1018.4316 0.58 109442 2832 2 1018.429836 510.2231 Vacuolar protein sorting-associated protein 4A OS=Homo sapiens OX=9606 GN=VPS4A PE=1 SV=1 4.25 1228.9 - 656514 - - - -1.6987 - 1.891 0.413 - 530.4 1 2 0 -0.0017 9 0 0 0 8.74E+06 1.51E+07 - - - 3.9341 0.8651 221125_WJC_METTL3_EV_vs_WT_F08.02835.02835.2 5.94 16-Jun K.TEGK[136.11]PAEVK[136.11].K "sp|P27816|MAP4_HUMAN,tr|H0Y2V1|H0Y2V1_HUMAN,tr|E7EVA0|E7EVA0_HUMAN,tr|H7C4C5|H7C4C5_HUMAN,tr|A0A804HKE7|A0A804HKE7_HUMAN,tr|B5MEG9|B5MEG9_HUMAN" 6 973.5415 0.52 109445 2835 2 973.540099 487.778 Microtubule-associated protein 4 OS=Homo sapiens OX=9606 GN=MAP4 PE=1 SV=3 5.81 1229.2 - 257511 - - - -1.4504 - 1.11 0.01 - 124.4 4 2 0 -0.0014 9 0 0 0 2.31E+06 4.48E+06 - - - -0.8526 0.978 221125_WJC_METTL3_EV_vs_WT_F08.02837.02837.2 0.15 16-Jul R.ITEAEK[136.11]NER[166.11].V "sp|P15311|EZRI_HUMAN,tr|E7EQR4|E7EQR4_HUMAN" 2 1106.5687 0.78 109447 2837 2 1106.566714 554.2916 Ezrin OS=Homo sapiens OX=9606 GN=EZR PE=1 SV=4 4.79 1229.5 - 91784.7 - - - -1.7694 - 1.567 0.265 - 177.3 1 2 1 -0.002 9 0 0 0 3.41E+06 4.39E+06 - - - 2.2971 0.9499 221125_WJC_METTL3_EV_vs_WT_F08.02842.02842.2 0.638 14-Aug R.AQEREQIK.V "sp|Q86Y46|K2C73_HUMAN,sp|Q7RTS7|K2C74_HUMAN,sp|Q3SY84|K2C71_HUMAN,sp|Q01546|K22O_HUMAN,sp|P12035|K2C3_HUMAN,sp|P35908|K22E_HUMAN,sp|Q14CN4|K2C72_HUMAN,tr|H0YHD9|H0YHD9_HUMAN,tr|F8W1S1|F8W1S1_HUMAN" 9 1000.5302 55.41 109450 2842 2 1000.527237 501.2724 "Keratin, type II cytoskeletal 73 OS=Homo sapiens OX=9606 GN=KRT73 PE=1 SV=1" 6.19 1230.1 - 1.47E+06 - - - -2.9195 - 1.605 0.245 - 263.3 1 2 1 -0.0029 8 0 0 0 3.62E+07 6.53E+05 - - - 2.2766 0.9969 221125_WJC_METTL3_EV_vs_WT_F08.02844.02844.2 0.00664 14-Aug R.EGHSINTR[166.11].E "sp|Q99700|ATX2_HUMAN,tr|F8W0B5|F8W0B5_HUMAN,tr|A0A5F9ZHW5|A0A5F9ZHW5_HUMAN,tr|A0A5F9ZHH4|A0A5F9ZHH4_HUMAN,tr|A0A5F9ZI57|A0A5F9ZI57_HUMAN,tr|A0A2R8YDM9|A0A2R8YDM9_HUMAN,tr|F8VQP2|F8VQP2_HUMAN,tr|A0A2R8Y5A6|A0A2R8Y5A6_HUMAN,tr|F8WB06|F8WB06_HUMAN,tr|A0A5F9ZH85|A0A5F9ZH85_HUMAN,tr|F8VRK6|F8VRK6_HUMAN,tr|V9GY86|V9GY86_HUMAN,tr|A0A2R8Y7E6|A0A2R8Y7E6_HUMAN,tr|A0A5F9ZHX3|A0A5F9ZHX3_HUMAN,tr|H0YH87|H0YH87_HUMAN,tr|A0A2R8Y7P6|A0A2R8Y7P6_HUMAN" 16 922.4496 0.21 109452 2844 2 922.447011 462.2321 Ataxin-2 OS=Homo sapiens OX=9606 GN=ATXN2 PE=1 SV=2 6.85 1230.2 - 1.03E+06 - - - -2.8208 - 1.449 0.326 - 206.2 1 2 0 -0.0026 8 0 0 0 4.15E+06 1.95E+07 - - - 2.5666 0.8974 221125_WJC_METTL3_EV_vs_WT_F08.02849.02849.2 0.935 16-Jun K.SEQVQGAQK.Q "sp|P23458|JAK1_HUMAN,tr|A0A5F9ZI39|A0A5F9ZI39_HUMAN,tr|A0A5F9ZH07|A0A5F9ZH07_HUMAN,tr|A0A5F9ZHN8|A0A5F9ZHN8_HUMAN,tr|A0A5F9ZH32|A0A5F9ZH32_HUMAN" 5 973.4829 0.25 109457 2849 2 973.479501 487.7487 Tyrosine-protein kinase JAK1 OS=Homo sapiens OX=9606 GN=JAK1 PE=1 SV=2 5.72 1230.8 - 264232 - - - -3.4639 - 1.309 0.085 - 113.9 3 2 0 -0.0034 9 0 0 0 6.65E+06 2.68E+07 - - - 0.2336 0.986 221125_WJC_METTL3_EV_vs_WT_F08.02853.02853.2 2.63E-05 22-Nov S.VSSSSTASASAK.K "sp|Q16836|HCDH_HUMAN,tr|A0A804HJW7|A0A804HJW7_HUMAN,tr|A0A1W2PP40|A0A1W2PP40_HUMAN,tr|E9PF18|E9PF18_HUMAN,tr|A0A0A0MSE2|A0A0A0MSE2_HUMAN,tr|A0A1W2PQV5|A0A1W2PQV5_HUMAN,tr|J3KR89|J3KR89_HUMAN,tr|A0A1W2PNM1|A0A1W2PNM1_HUMAN,tr|A0A1W2PQ78|A0A1W2PQ78_HUMAN" 9 1081.5251 1.04 109459 2853 2 1081.522809 541.7698 "Hydroxyacyl-coenzyme A dehydrogenase, mitochondrial OS=Homo sapiens OX=9606 GN=HADH PE=1 SV=3" 8.72 1231.3 - 1.31E+06 - - - -2.1479 - 2.455 0.521 - 495.4 1 1 0 -0.0023 12 0 0 0 2.03E+07 1.94E+07 - - - 5.2515 0.9818 221125_WJC_METTL3_EV_vs_WT_F08.02854.02854.2 1.67 14-Jul R.STMKPVQK.V "sp|P11021|BIP_HUMAN,tr|A0A7P0TB36|A0A7P0TB36_HUMAN" 2 917.5004 0.46 109460 2854 2 917.499666 459.7575 Endoplasmic reticulum chaperone BiP OS=Homo sapiens OX=9606 GN=HSPA5 PE=1 SV=2 10 1231.3 - 2.59E+06 - - - -0.8414 - 1.46 0.058 - 169.8 5 2 0 -0.0008 8 0 0 0 3.88E+07 8.52E+07 - - - 0.2983 0.9888 221125_WJC_METTL3_EV_vs_WT_F08.02857.02857.2 1.02 12-Sep R.KQHSLLK.R "sp|P62841|RS15_HUMAN,tr|K7EJ78|K7EJ78_HUMAN,tr|K7EM56|K7EM56_HUMAN,tr|A0A0B4J2B4|A0A0B4J2B4_HUMAN,tr|S4R456|S4R456_HUMAN,tr|K7ELC2|K7ELC2_HUMAN,tr|K7EQJ5|K7EQJ5_HUMAN,tr|S4R417|S4R417_HUMAN" 8 852.5181 1.47 109463 2857 2 852.51553 427.2663 40S ribosomal protein S15 OS=Homo sapiens OX=9606 GN=RPS15 PE=1 SV=2 10 1231.5 - 1.40E+06 - - - -3.058 - 1.761 0.109 - 324.8 1 2 0 -0.0026 7 0 0 0 2.14E+07 1.45E+07 - - - 1.6383 0.9983 221125_WJC_METTL3_EV_vs_WT_F08.02858.02858.2 0.0416 12-Dec R.K[136.11]QHSLLK[136.11].R "sp|P62841|RS15_HUMAN,tr|K7EJ78|K7EJ78_HUMAN,tr|K7EM56|K7EM56_HUMAN,tr|A0A0B4J2B4|A0A0B4J2B4_HUMAN,tr|S4R456|S4R456_HUMAN,tr|K7ELC2|K7ELC2_HUMAN,tr|K7EQJ5|K7EQJ5_HUMAN,tr|S4R417|S4R417_HUMAN" 8 868.5465 1.49 109464 2858 2 868.544253 435.2805 40S ribosomal protein S15 OS=Homo sapiens OX=9606 GN=RPS15 PE=1 SV=2 10 1231.7 - 925778 - - - -2.6297 - 2.343 0.172 - 666.6 1 2 0 -0.0023 7 0 0 0 2.12E+07 1.42E+07 - - - 3.0085 0.9996 221125_WJC_METTL3_EV_vs_WT_F08.02864.02864.2 3.23E-05 18-Aug R.GVSSESSGDR[166.11].E "sp|Q13435|SF3B2_HUMAN,tr|E9PPJ0|E9PPJ0_HUMAN,tr|H0YCG1|H0YCG1_HUMAN,tr|E9PJ04|E9PJ04_HUMAN" 4 989.4289 1.07 109468 2864 2 989.426301 495.7217 Splicing factor 3B subunit 2 OS=Homo sapiens OX=9606 GN=SF3B2 PE=1 SV=2 4.37 1232.4 - 2.15E+06 - - - -2.6642 - 1.893 0.545 - 171.9 1 2 0 -0.0026 10 0 0 0 3.69E+07 3.44E+07 - - - 4.8468 0.9755 221125_WJC_METTL3_EV_vs_WT_F08.02865.02865.2 0.000231 22-Oct S.VSSSSTASASAK[136.11].K "sp|Q16836|HCDH_HUMAN,tr|A0A804HJW7|A0A804HJW7_HUMAN,tr|A0A1W2PP40|A0A1W2PP40_HUMAN,tr|E9PF18|E9PF18_HUMAN,tr|A0A0A0MSE2|A0A0A0MSE2_HUMAN,tr|A0A1W2PQV5|A0A1W2PQV5_HUMAN,tr|J3KR89|J3KR89_HUMAN,tr|A0A1W2PNM1|A0A1W2PNM1_HUMAN,tr|A0A1W2PQ78|A0A1W2PQ78_HUMAN" 9 1089.5393 1.04 109469 2865 2 1089.536414 545.7769 "Hydroxyacyl-coenzyme A dehydrogenase, mitochondrial OS=Homo sapiens OX=9606 GN=HADH PE=1 SV=3" 8.72 1232.5 - 1.83E+06 - - - -2.6782 - 2.359 0.487 - 341.1 1 1 0 -0.0029 12 0 0 0 2.03E+07 1.94E+07 - - - 4.8952 0.9602 221125_WJC_METTL3_EV_vs_WT_F08.02866.02866.2 0.0809 16-Jun R.KGGVGMPSR.D "sp|Q92888|ARHG1_HUMAN,tr|M0QZR4|M0QZR4_HUMAN,tr|M0QZH8|M0QZH8_HUMAN" 3 887.4647 18.66 109470 2866 2 887.467429 444.7396 Rho guanine nucleotide exchange factor 1 OS=Homo sapiens OX=9606 GN=ARHGEF1 PE=1 SV=2 11 1232.5 - 1.68E+06 - - - 3.0514 - 1.414 0.139 - 110.1 6 2 0 0.0027 9 0 0 0 1.98E+07 1.06E+06 - - - 0.7214 0.9985 221125_WJC_METTL3_EV_vs_WT_F08.02869.02869.2 0.0129 14-Aug K.AYEEAQK[136.11]R[166.11].L "sp|O60231|DHX16_HUMAN,tr|A0A140T947|A0A140T947_HUMAN,tr|A2AB15|A2AB15_HUMAN" 3 1011.5104 2.39 109473 2869 2 1011.508254 506.7625 Pre-mRNA-splicing factor ATP-dependent RNA helicase DHX16 OS=Homo sapiens OX=9606 GN=DHX16 PE=1 SV=2 6.19 1232.8 - 741685 - - - -2.1502 - 1.519 0.338 - 289.2 1 2 0 -0.0022 8 0 0 0 1.90E+07 7.94E+06 - - - 2.7976 0.9849 221125_WJC_METTL3_EV_vs_WT_F08.02879.02879.2 0.223 14-Jul R.ELTNDER[166.11]K[136.11].Q sp|O15226|NKRF_HUMAN 1 1021.5159 1.25 109481 2879 2 1021.512641 511.7652 NF-kappa-B-repressing factor OS=Homo sapiens OX=9606 GN=NKRF PE=1 SV=2 4.68 1233.9 - 574655 - - - -3.1982 - 1.302 0.224 - 214 1 2 0 -0.0033 8 0 0 0 6.62E+06 5.29E+06 - - - 1.4904 0.9979 221125_WJC_METTL3_EV_vs_WT_F08.02880.02880.2 0.000273 18-Aug K.AGEQQETASR.E "sp|Q14980|NUMA1_HUMAN,tr|A0A087WY61|A0A087WY61_HUMAN" 2 1075.4894 1.24 109482 2880 2 1075.485736 538.752 Nuclear mitotic apparatus protein 1 OS=Homo sapiens OX=9606 GN=NUMA1 PE=1 SV=2 4.53 1234 - 270953 - - - -3.4208 - 1.72 0.384 - 273.7 1 2 0 -0.0037 10 0 0 0 4.06E+06 3.28E+06 - - - 3.3899 0.9981 221125_WJC_METTL3_EV_vs_WT_F08.02882.02882.2 2.49E-05 18-Sep R.GVSSESSGDR.E "sp|Q13435|SF3B2_HUMAN,tr|E9PPJ0|E9PPJ0_HUMAN,tr|H0YCG1|H0YCG1_HUMAN,tr|E9PJ04|E9PJ04_HUMAN" 4 979.4207 1.07 109483 2882 2 979.417624 490.7176 Splicing factor 3B subunit 2 OS=Homo sapiens OX=9606 GN=SF3B2 PE=1 SV=2 4.37 1234.2 - 3.52E+06 - - - -3.1069 - 2.008 0.309 - 243.8 1 2 0 -0.003 10 0 0 0 3.69E+07 3.44E+07 - - - 3.2682 0.977 221125_WJC_METTL3_EV_vs_WT_F08.02886.02886.2 0.000698 20-Dec K.QSHGAAPC[160.03]SGG.S "sp|Q86SG5|S1A7A_HUMAN,sp|P31151|S10A7_HUMAN" 2 1027.4141 - 109486 2886 2 1027.41186 514.7143 Protein S100-A7A OS=Homo sapiens OX=9606 GN=S100A7A PE=1 SV=3 6.73 1234.7 - 456676 - - - -2.2211 - 2.177 0.447 - 553.6 1 1 0 -0.0023 11 0 0 0 - - - - - 4.4464 0.9736 221125_WJC_METTL3_EV_vs_WT_F08.02889.02889.2 0.0312 12-Oct R.RQEQTLR.D "sp|P58107|EPIPL_HUMAN,sp|P58107|EPIPL_HUMAN,sp|P58107|EPIPL_HUMAN,sp|P58107|EPIPL_HUMAN,sp|P58107|EPIPL_HUMAN,tr|A0A075B730|A0A075B730_HUMAN,tr|A0A075B730|A0A075B730_HUMAN,tr|A0A075B730|A0A075B730_HUMAN,tr|A0A075B730|A0A075B730_HUMAN,tr|A0A075B730|A0A075B730_HUMAN" 10 929.5043 1.97 109487 2889 2 929.502112 465.7594 Epiplakin OS=Homo sapiens OX=9606 GN=EPPK1 PE=1 SV=3 9.6 1235.1 - 5.74E+06 - - - -2.3303 - 1.646 0.002 - 262.3 1 2 0 -0.0022 7 0 0 0 8.76E+07 4.45E+07 - - - 0.6341 0.9912 221125_WJC_METTL3_EV_vs_WT_F08.02892.02892.2 0.00215 16-Oct K.TLSKEEETK.K "sp|P84098|RL19_HUMAN,tr|J3KTE4|J3KTE4_HUMAN,tr|A0A7I2YQG2|A0A7I2YQG2_HUMAN,tr|J3QR09|J3QR09_HUMAN" 4 1063.5397 1.23 109490 2892 2 1063.537219 532.7771 60S ribosomal protein L19 OS=Homo sapiens OX=9606 GN=RPL19 PE=1 SV=1 4.78 1235.4 - 303335 - - - -2.3516 - 1.531 0.456 - 299.3 1 2 1 -0.0025 9 0 0 0 3.88E+06 3.15E+06 - - - 3.6404 0.7967 221125_WJC_METTL3_EV_vs_WT_F08.02898.02898.2 0.817 12-Aug K.NK[136.11]YNTPK[136.11].Y "sp|P46777|RL5_HUMAN,tr|A0A2R8Y4A2|A0A2R8Y4A2_HUMAN,tr|R4GNJ2|R4GNJ2_HUMAN" 3 879.4785 1.09 109494 2898 2 879.476261 440.7465 60S ribosomal protein L5 OS=Homo sapiens OX=9606 GN=RPL5 PE=1 SV=3 9.7 1236 - 1.08E+06 - - - -2.5652 - 1.176 0.178 - 197.1 1 2 1 -0.0023 7 0 0 0 2.28E+07 2.09E+07 - - - 0.8687 0.9987 221125_WJC_METTL3_EV_vs_WT_F08.02900.02900.2 0.0698 14-Aug K.C[160.03]SQTQC[160.03]PR.K "sp|P29590|PML_HUMAN,tr|H3BRN3|H3BRN3_HUMAN,tr|H3BUJ5|H3BUJ5_HUMAN,tr|H3BVD2|H3BVD2_HUMAN,tr|H3BT57|H3BT57_HUMAN" 5 1035.4226 0.64 109496 2900 2 1035.419856 518.7186 Protein PML OS=Homo sapiens OX=9606 GN=PML PE=1 SV=3 8.07 1236.2 - 424012 - - - -2.6492 - 1.719 0.357 - 253.3 1 2 0 -0.0027 8 0 0 0 1.19E+07 1.87E+07 - - - 3.3108 0.9994 221125_WJC_METTL3_EV_vs_WT_F08.02905.02905.2 0.00553 16-Sep K.NSQGGPAPR.E "sp|Q9UPQ9|TNR6B_HUMAN,tr|H0Y720|H0Y720_HUMAN" 2 882.4308 2.08 109499 2905 2 882.429244 442.2227 Trinucleotide repeat-containing gene 6B protein OS=Homo sapiens OX=9606 GN=TNRC6B PE=1 SV=4 9.75 1236.9 - 1.66E+06 - - - -1.7384 - 1.82 0.368 - 374.8 1 2 0 -0.0015 9 0 0 0 7.05E+07 3.39E+07 - - - 3.491 0.9993 221125_WJC_METTL3_EV_vs_WT_F08.02907.02907.2 1.17 14-Nov K.KGPAAIQK.N sp|P35527|K1C9_HUMAN 1 811.4916 3210.53 109501 2907 2 811.489477 406.7531 "Keratin, type I cytoskeletal 9 OS=Homo sapiens OX=9606 GN=KRT9 PE=1 SV=3" 10 1237.1 - 1.35E+06 - - - -2.6014 - 2.286 0.336 - 423.8 1 2 0 -0.0021 8 0 0 0 7.59E+08 2.36E+05 - - - 4.0156 0.9981 221125_WJC_METTL3_EV_vs_WT_F08.02908.02908.2 0.0012 14-Aug K.EIQGHQPR.L "sp|Q01082|SPTB2_HUMAN,tr|A0A087WUZ3|A0A087WUZ3_HUMAN" 2 963.4886 1.75 109502 2908 2 963.486404 482.7516 "Spectrin beta chain, non-erythrocytic 1 OS=Homo sapiens OX=9606 GN=SPTBN1 PE=1 SV=2" 6.85 1237.1 - 1.06E+06 - - - -2.3072 - 1.476 0.333 - 335.7 1 2 0 -0.0022 8 0 0 0 2.64E+07 1.51E+07 - - - 2.6741 0.9959 221125_WJC_METTL3_EV_vs_WT_F08.02915.02915.2 0.0618 14-Jun K.HISPGDTK.V "sp|P24928|RPB1_HUMAN,tr|A0A6Q8PGB0|A0A6Q8PGB0_HUMAN" 2 853.4294 1.04 109507 2915 2 853.427877 427.722 DNA-directed RNA polymerase II subunit RPB1 OS=Homo sapiens OX=9606 GN=POLR2A PE=1 SV=2 6.74 1238 - 4.06E+06 - - - -1.7623 - 1.421 0.216 - 147.1 1 2 0 -0.0015 8 0 0 0 6.28E+07 6.06E+07 - - - 1.6956 0.9994 221125_WJC_METTL3_EV_vs_WT_F08.02917.02917.2 0.00446 16-Sep K.QQEQPAATK[136.11].L sp|P40937|RFC5_HUMAN 1 1007.5127 0.98 109509 2917 2 1007.511068 504.7636 Replication factor C subunit 5 OS=Homo sapiens OX=9606 GN=RFC5 PE=1 SV=1 6 1238.2 - 1.24E+06 - - - -1.6427 - 1.662 0.38 - 391.4 1 2 0 -0.0017 9 0 0 0 4.16E+07 4.26E+07 - - - 3.3169 0.9988 221125_WJC_METTL3_EV_vs_WT_F08.02918.02918.2 0.00221 16-Sep K.QQEQPAATK.L sp|P40937|RFC5_HUMAN 1 999.4985 1.02 109510 2918 2 999.496221 500.7565 Replication factor C subunit 5 OS=Homo sapiens OX=9606 GN=RFC5 PE=1 SV=1 6 1238.2 - 979765 - - - -2.3032 - 1.544 0.384 - 269.2 1 2 0 -0.0023 9 0 0 0 4.15E+07 4.07E+07 - - - 3.1332 0.9927 221125_WJC_METTL3_EV_vs_WT_F08.02924.02924.2 0.00486 14-Aug R.SNVTAVHK.A "sp|P50213|IDH3A_HUMAN,tr|H0YL72|H0YL72_HUMAN,tr|H0YMU3|H0YMU3_HUMAN" 3 854.461 1.35 109514 2924 2 854.458643 428.2378 "Isocitrate dehydrogenase [NAD] subunit alpha, mitochondrial OS=Homo sapiens OX=9606 GN=IDH3A PE=1 SV=1" 8.49 1239 - 4.98E+06 - - - -2.7772 - 1.688 0.163 - 279.9 1 2 0 -0.0024 8 0 0 0 4.80E+07 3.56E+07 - - - 1.8232 0.9018 221125_WJC_METTL3_EV_vs_WT_F08.02925.02925.2 0.3 14-Sep R.VR[166.11]VDSTAK[136.11].V "sp|P78371|TCPB_HUMAN,tr|F8VQ14|F8VQ14_HUMAN,tr|F5GWF6|F5GWF6_HUMAN" 3 892.5097 0.52 109515 2925 2 892.507103 447.2621 T-complex protein 1 subunit beta OS=Homo sapiens OX=9606 GN=CCT2 PE=1 SV=4 8.72 1239.1 - 2.17E+06 - - - -2.9109 - 1.506 0.19 - 273.3 1 2 1 -0.0026 8 0 0 0 3.04E+07 5.88E+07 - - - 1.6784 0.9944 221125_WJC_METTL3_EV_vs_WT_F08.02926.02926.2 5.38 16-Aug K.SESEATSER.V "sp|Q15390|MTFR1_HUMAN,tr|H0YBZ4|H0YBZ4_HUMAN,tr|H7C5V5|H7C5V5_HUMAN,tr|H0YF01|H0YF01_HUMAN" 4 994.4203 1.34 109516 2926 2 994.418606 498.2174 Mitochondrial fission regulator 1 OS=Homo sapiens OX=9606 GN=MTFR1 PE=1 SV=2 4.25 1239.1 - 1.93E+06 - - - -1.7367 - 1.618 0.137 - 287.2 1 2 0 -0.0017 9 0 0 0 4.27E+07 3.19E+07 - - - 1.4445 0.9983 221125_WJC_METTL3_EV_vs_WT_F08.02927.02927.2 0.00335 14-Jul R.SYSPAHNR.E "sp|Q9Y2W1|TR150_HUMAN,tr|A0A3B3ITZ9|A0A3B3ITZ9_HUMAN" 2 930.4308 1.08 109517 2927 2 930.428333 466.2227 Thyroid hormone receptor-associated protein 3 OS=Homo sapiens OX=9606 GN=THRAP3 PE=1 SV=2 8.49 1239.2 - 1.81E+06 - - - -2.6278 - 1.327 0.421 - 194.8 1 2 0 -0.0024 8 0 0 0 5.65E+07 5.25E+07 - - - 3.003 0.9485 221125_WJC_METTL3_EV_vs_WT_F08.02928.02928.2 5.39 14-Aug K.KENLSK[136.11]NK.A sp|Q5T0W9|FA83B_HUMAN 1 967.5542 - 109518 2928 2 967.554784 484.7844 Protein FAM83B OS=Homo sapiens OX=9606 GN=FAM83B PE=1 SV=1 9.7 1239.3 - 1.78E+06 - - - 0.6098 - 1.667 0.104 - 209.4 2 2 1 0.0006 8 0 0 0 - - - - - 1.2157 0.9984 221125_WJC_METTL3_EV_vs_WT_F08.02929.02929.2 0.00707 14-Oct R.K[136.11]VEPVTQK[136.11].D "sp|O43491|E41L2_HUMAN,tr|Q6R5J7|Q6R5J7_HUMAN,tr|E9PHY5|E9PHY5_HUMAN,tr|E9PMV8|E9PMV8_HUMAN,tr|E9PMG5|E9PMG5_HUMAN,tr|H0Y5B0|H0Y5B0_HUMAN,tr|E9PK52|E9PK52_HUMAN" 7 943.5673 5.3 109519 2929 2 943.564573 472.7909 Band 4.1-like protein 2 OS=Homo sapiens OX=9606 GN=EPB41L2 PE=1 SV=1 8.59 1239.3 - 1.70E+06 - - - -2.924 - 1.786 0.343 - 356.2 1 2 0 -0.0028 8 0 0 0 1.13E+08 2.14E+07 - - - 3.3227 0.9829 221125_WJC_METTL3_EV_vs_WT_F08.02930.02930.2 0.194 12-Jun K.RQPAPPR.E sp|P46778|RL21_HUMAN 1 820.4668 0.99 109520 2930 2 820.463835 411.2407 60S ribosomal protein L21 OS=Homo sapiens OX=9606 GN=RPL21 PE=1 SV=2 12 1239.4 - 1.64E+06 - - - -3.5772 - 1.284 0.24 - 88.6 1 2 0 -0.0029 7 0 0 0 7.10E+07 7.17E+07 - - - 1.6048 0.9983 221125_WJC_METTL3_EV_vs_WT_F08.02931.02931.2 0.0174 14-Aug R.QVQDESQR.K sp|Q15149|PLEC_HUMAN 1 988.4574 1.15 109521 2931 2 988.455026 495.236 Plectin OS=Homo sapiens OX=9606 GN=PLEC PE=1 SV=3 4.37 1239.5 - 1.42E+06 - - - -2.3886 - 1.611 0.324 - 361.7 1 2 0 -0.0024 8 0 0 0 1.22E+07 1.06E+07 - - - 2.8715 0.9953 221125_WJC_METTL3_EV_vs_WT_F08.02937.02937.2 0.232 14-Aug R.LR[166.11]PVNQNK[136.11].T "sp|P51114|FXR1_HUMAN,tr|E7EU85|E7EU85_HUMAN,tr|E9PFF5|E9PFF5_HUMAN,tr|C9IZ22|C9IZ22_HUMAN,tr|C9JZE0|C9JZE0_HUMAN,tr|C9JY20|C9JY20_HUMAN,tr|C9J5B4|C9J5B4_HUMAN,tr|C9JAJ4|C9JAJ4_HUMAN,tr|B4DXZ6|B4DXZ6_HUMAN" 9 985.5788 1.63 109525 2937 2 985.575161 493.7967 Fragile X mental retardation syndrome-related protein 1 OS=Homo sapiens OX=9606 GN=FXR1 PE=1 SV=3 11 1240.2 - 2.02E+06 - - - -3.675 - 1.563 0.324 - 233.2 1 2 0 -0.0036 8 0 0 0 4.73E+07 2.89E+07 - - - 2.7799 0.8158 221125_WJC_METTL3_EV_vs_WT_F08.02938.02938.2 1.31 14-Jul R.VRVDSTAK.V "sp|P78371|TCPB_HUMAN,tr|F8VQ14|F8VQ14_HUMAN,tr|F5GWF6|F5GWF6_HUMAN" 3 874.4872 0.52 109526 2938 2 874.484996 438.2509 T-complex protein 1 subunit beta OS=Homo sapiens OX=9606 GN=CCT2 PE=1 SV=4 8.72 1240.2 - 1.67E+06 - - - -2.5546 - 1.595 0.119 - 128.3 7 2 1 -0.0022 8 0 0 0 3.04E+07 5.88E+07 - - - 0.9498 0.9975 221125_WJC_METTL3_EV_vs_WT_F08.02942.02942.2 2.58E-05 18-Oct R.YEGHPAEGTK.S "sp|P49750|YLPM1_HUMAN,tr|H0YIQ2|H0YIQ2_HUMAN" 2 1087.4934 2.49 109530 2942 2 1087.488246 544.754 YLP motif-containing protein 1 OS=Homo sapiens OX=9606 GN=YLPM1 PE=1 SV=4 5.4 1240.6 - 601828 - - - -4.7743 - 1.969 0.483 - 319.7 1 2 0 -0.0052 10 0 0 0 1.30E+07 5.21E+06 - - - 4.498 0.999 221125_WJC_METTL3_EV_vs_WT_F08.02944.02944.2 0.000355 14-Nov R.C[160.03]QHLQAEK[136.11].K sp|P35579|MYH9_HUMAN 1 1020.4902 1.11 109532 2944 2 1020.486471 511.2524 Myosin-9 OS=Homo sapiens OX=9606 GN=MYH9 PE=1 SV=4 6.74 1240.8 - 520014 - - - -3.6678 - 2.072 0.458 - 600.1 1 2 0 -0.0037 8 0 0 0 4.84E+07 4.35E+07 - - - 4.6198 0.9917 221125_WJC_METTL3_EV_vs_WT_F08.02947.02947.2 0.372 16-Jul R.VATHSSNIR.S "sp|Q8IWC1|MA7D3_HUMAN,tr|A0A0A0MRP0|A0A0A0MRP0_HUMAN" 2 983.5148 1.15 109533 2947 2 983.511637 492.7647 MAP7 domain-containing protein 3 OS=Homo sapiens OX=9606 GN=MAP7D3 PE=1 SV=2 9.73 1241.2 - 2.81E+06 - - - -3.2587 - 1.493 0.244 - 215.8 1 2 0 -0.0032 9 0 0 0 2.59E+07 2.25E+07 - - - 2.0017 0.9712 221125_WJC_METTL3_EV_vs_WT_F08.02948.02948.2 0.00481 14-Aug R.SK[136.11]GQESFK[136.11].K "sp|P06748|NPM_HUMAN,tr|E5RI98|E5RI98_HUMAN,tr|A0A7I2V5S2|A0A7I2V5S2_HUMAN" 3 925.484 0.79 109534 2948 2 925.480685 463.7493 Nucleophosmin OS=Homo sapiens OX=9606 GN=NPM1 PE=1 SV=2 8.31 1241.3 - 3.10E+06 - - - -3.5776 - 1.584 0.388 - 142.8 1 2 1 -0.0033 8 0 0 0 2.67E+08 3.38E+08 - - - 3.2929 0.9943 221125_WJC_METTL3_EV_vs_WT_F08.02954.02954.2 0.0138 12-Jul R.DHLGDNR.T sp|Q9BQ67|GRWD1_HUMAN 1 825.3729 1.07 109538 2954 2 825.369836 413.6937 Glutamate-rich WD repeat-containing protein 1 OS=Homo sapiens OX=9606 GN=GRWD1 PE=1 SV=1 5.21 1242 - 2.14E+06 - - - -3.7474 - 1.459 0.326 - 289.4 1 2 0 -0.0031 7 0 0 0 2.72E+07 2.53E+07 - - - 2.6448 0.9984 221125_WJC_METTL3_EV_vs_WT_F08.02955.02955.2 0.00628 12-Aug K.K[136.11]LEDGPK[136.11].F "sp|P68104|EF1A1_HUMAN,sp|Q5VTE0|EF1A3_HUMAN,tr|A0A7I2V659|A0A7I2V659_HUMAN,tr|A0A7I2V5N4|A0A7I2V5N4_HUMAN,tr|A0A087WVQ9|A0A087WVQ9_HUMAN,tr|A0A087WV01|A0A087WV01_HUMAN" 6 801.4567 0.43 109539 2955 2 801.454831 401.7356 Elongation factor 1-alpha 1 OS=Homo sapiens OX=9606 GN=EEF1A1 PE=1 SV=1 6.07 1242.1 - 1.68E+06 - - - -2.3557 - 1.676 0.303 - 227.7 1 2 0 -0.0019 7 0 0 0 2.59E+07 6.02E+07 - - - 2.9146 0.9997 221125_WJC_METTL3_EV_vs_WT_F08.02960.02960.2 3.37E-06 18-Oct K.LNQEGSDNEK.L "sp|Q86VS8|HOOK3_HUMAN,tr|H0YE69|H0YE69_HUMAN" 2 1132.4996 3.87 109542 2960 2 1132.496661 567.2571 Protein Hook homolog 3 OS=Homo sapiens OX=9606 GN=HOOK3 PE=1 SV=2 4.14 1242.7 - 2.39E+06 - - - -2.6358 - 1.987 0.619 - 341 1 2 0 -0.003 10 0 0 0 3.53E+07 9.11E+06 - - - 5.5286 0.9953 221125_WJC_METTL3_EV_vs_WT_F08.02961.02961.2 0.0999 16-Sep K.KPVPPSEGK.S "sp|Q9BXK5|B2L13_HUMAN,tr|A0A087WX97|A0A087WX97_HUMAN,tr|A0A087WTL4|A0A087WTL4_HUMAN" 3 937.5233 1.84 109543 2961 2 937.519988 469.7689 Bcl-2-like protein 13 OS=Homo sapiens OX=9606 GN=BCL2L13 PE=1 SV=1 8.59 1242.8 - 1.31E+06 - - - -3.5135 - 1.874 0.245 - 285.2 1 2 0 -0.0033 9 0 0 0 5.33E+07 2.90E+07 - - - 2.6666 0.9995 221125_WJC_METTL3_EV_vs_WT_F08.02965.02965.2 4.39E-05 18-Nov K.LNQEGSDNEK[136.11].L "sp|Q86VS8|HOOK3_HUMAN,tr|H0YE69|H0YE69_HUMAN" 2 1140.5138 3.87 109545 2965 2 1140.510652 571.2642 Protein Hook homolog 3 OS=Homo sapiens OX=9606 GN=HOOK3 PE=1 SV=2 4.14 1243.3 - 635316 - - - -2.8005 - 2.003 0.53 - 422.9 1 2 0 -0.0032 10 0 0 0 3.53E+07 9.11E+06 - - - 4.8935 0.9986 221125_WJC_METTL3_EV_vs_WT_F08.02966.02966.2 0.00439 16-Aug R.QHEAEEGVR.R "sp|Q15149|PLEC_HUMAN,tr|H0YDN1|H0YDN1_HUMAN" 2 1053.4839 1.24 109546 2966 2 1053.480613 527.7492 Plectin OS=Homo sapiens OX=9606 GN=PLEC PE=1 SV=3 4.75 1243.5 - 590835 - - - -3.1543 - 1.495 0.465 - 301.7 1 2 0 -0.0033 9 0 0 0 5.26E+06 4.25E+06 - - - 3.6378 0.9887 221125_WJC_METTL3_EV_vs_WT_F08.02967.02967.2 0.000166 18-Oct Y.GSGSSSGGYR.G sp|P04264|K2C1_HUMAN 1 913.389 19.94 109547 2967 2 913.3875 457.7018 "Keratin, type II cytoskeletal 1 OS=Homo sapiens OX=9606 GN=KRT1 PE=1 SV=6" 8.75 1243.5 - 5.39E+06 - - - -1.6127 - 2.053 0.53 - 544.3 1 1 0 -0.0015 10 0 0 0 1.65E+08 8.25E+06 - - - 4.9629 0.9975 221125_WJC_METTL3_EV_vs_WT_F08.02968.02968.2 0.388 12-Jun K.KLEDGPK.F "sp|P68104|EF1A1_HUMAN,sp|Q5VTE0|EF1A3_HUMAN,tr|A0A7I2V659|A0A7I2V659_HUMAN,tr|A0A7I2V5N4|A0A7I2V5N4_HUMAN,tr|A0A087WVQ9|A0A087WVQ9_HUMAN,tr|A0A087WV01|A0A087WV01_HUMAN" 6 785.4283 0.43 109548 2968 2 785.427689 393.7214 Elongation factor 1-alpha 1 OS=Homo sapiens OX=9606 GN=EEF1A1 PE=1 SV=1 6.07 1243.6 - 740533 - - - -0.8021 - 1.319 0.242 - 132.7 1 2 0 -0.0006 7 0 0 0 2.59E+07 6.02E+07 - - - 1.7055 0.998 221125_WJC_METTL3_EV_vs_WT_F08.02969.02969.2 0.00446 16-Jul R.QHEAEEGVR[166.11].R "sp|Q15149|PLEC_HUMAN,tr|H0YDN1|H0YDN1_HUMAN" 2 1063.4922 1.25 109549 2969 2 1063.490883 532.7534 Plectin OS=Homo sapiens OX=9606 GN=PLEC PE=1 SV=3 4.75 1243.7 - 342160 - - - -1.244 - 1.42 0.268 - 189 1 2 0 -0.0013 9 0 0 0 5.26E+06 4.21E+06 - - - 2.0345 0.9981 221125_WJC_METTL3_EV_vs_WT_F08.02972.02972.2 0.00345 16-Jul R.QNSVADTNK[136.11].T "sp|Q13613|MTMR1_HUMAN,tr|Q8NEC6|Q8NEC6_HUMAN,tr|F8WA39|F8WA39_HUMAN,tr|H0YDX3|H0YDX3_HUMAN" 4 983.4763 0.32 109550 2972 2 983.473304 492.7454 Myotubularin-related protein 1 OS=Homo sapiens OX=9606 GN=MTMR1 PE=1 SV=4 5.84 1244.1 - 2.26E+06 - - - -3.085 - 1.498 0.413 - 183.9 1 2 0 -0.003 9 0 0 0 1.20E+07 3.79E+07 - - - 3.2596 0.9355 221125_WJC_METTL3_EV_vs_WT_F08.02975.02975.2 0.0103 20-Sep K.LSSTTQNNTGK.P "sp|Q96CB8|INT12_HUMAN,tr|A0A087WXN4|A0A087WXN4_HUMAN" 2 1149.5626 1.25 109553 2975 2 1149.559097 575.7886 Integrator complex subunit 12 OS=Homo sapiens OX=9606 GN=INTS12 PE=1 SV=1 8.75 1244.4 - 243373 - - - -3.0298 - 1.784 0.431 - 209.7 1 1 0 -0.0035 11 0 0 0 2.88E+06 2.31E+06 - - - 3.7892 0.987 221125_WJC_METTL3_EV_vs_WT_F08.02981.02981.2 0.0798 14-Jul K.SNLTEHEK[136.11].L "sp|Q3ZCX4|ZN568_HUMAN,sp|Q3ZCT1|ZN260_HUMAN,sp|Q15072|OZF_HUMAN,tr|A0A0C4DGP9|A0A0C4DGP9_HUMAN" 4 964.4705 0.7 109557 2981 2 964.466444 483.2425 Zinc finger protein 568 OS=Homo sapiens OX=9606 GN=ZNF568 PE=2 SV=2 5.38 1245.1 - 1.44E+06 - - - -4.2303 - 1.477 0.271 - 246.9 1 2 0 -0.0041 8 0 0 0 3.82E+07 5.50E+07 - - - 2.2176 0.9975 221125_WJC_METTL3_EV_vs_WT_F08.02983.02983.2 0.0101 16-Oct K.K[136.11]PVPPSEGK[136.11].S "sp|Q9BXK5|B2L13_HUMAN,tr|A0A087WX97|A0A087WX97_HUMAN,tr|A0A087WTL4|A0A087WTL4_HUMAN" 3 953.5517 1.7 109559 2983 2 953.549506 477.7831 Bcl-2-like protein 13 OS=Homo sapiens OX=9606 GN=BCL2L13 PE=1 SV=1 8.59 1245.3 - 670273 - - - -2.282 - 1.69 0.25 - 321.4 1 2 0 -0.0022 9 0 0 0 2.11E+07 1.24E+07 - - - 2.4049 0.9425 221125_WJC_METTL3_EV_vs_WT_F08.02990.02990.2 0.176 16-Jul R.QQGPGTGTR.D sp|Q9Y6J9|TAF6L_HUMAN 1 900.4413 0.38 109564 2990 2 900.445447 451.2279 TAF6-like RNA polymerase II p300\CBP-associated factor-associated factor 65 kDa subunit 6L OS=Homo sapiens OX=9606 GN=TAF6L PE=1 SV=1 9.75 1246.2 - 576034 - - - 4.5578 - 1.328 0.185 - 144.1 1 2 0 0.0041 9 0 0 0 6.42E+07 1.71E+08 - - - 1.2268 0.9058 221125_WJC_METTL3_EV_vs_WT_F08.02991.02991.2 0.106 12-Jul K.NTLPSHK.E "sp|P0DPB5|RPC22_HUMAN,tr|A0A087WTY1|A0A087WTY1_HUMAN" 2 795.4239 1.11 109565 2991 2 795.42118 398.7192 "Protein POLR1D, isoform 2 OS=Homo sapiens OX=9606 GN=POLR1D PE=1 SV=1" 8.76 1246.3 - 566236 - - - -3.4221 - 1.419 0.017 - 221.7 1 2 0 -0.0027 7 0 0 0 2.34E+07 2.12E+07 - - - 0.2746 0.9942 221125_WJC_METTL3_EV_vs_WT_F08.02996.02996.2 0.0148 12-Aug K.K[136.11]FEDSEK[136.11].A sp|P08240|SRPRA_HUMAN 1 897.4415 0.62 109568 2996 2 897.438868 449.728 Signal recognition particle receptor subunit alpha OS=Homo sapiens OX=9606 GN=SRPRA PE=1 SV=2 4.68 1246.8 - 1.02E+06 - - - -2.8916 - 1.943 0.126 - 210.9 1 2 0 -0.0026 7 0 0 0 1.36E+07 2.21E+07 - - - 2.0755 0.9995 221125_WJC_METTL3_EV_vs_WT_F08.02997.02997.2 7.80E-05 16-Nov K.KSTLNPNAK.E "sp|Q8WWM7|ATX2L_HUMAN,sp|Q99700|ATX2_HUMAN,tr|F8W0B5|F8W0B5_HUMAN,tr|A0A5F9ZHW5|A0A5F9ZHW5_HUMAN,tr|A0A5F9ZHH4|A0A5F9ZHH4_HUMAN,tr|F8WB05|F8WB05_HUMAN,tr|A0A5F9ZI57|A0A5F9ZI57_HUMAN,tr|A0A2R8YDM9|A0A2R8YDM9_HUMAN,tr|H3BUF6|H3BUF6_HUMAN,tr|F8VQP2|F8VQP2_HUMAN,tr|A0A2R8Y5A6|A0A2R8Y5A6_HUMAN,tr|S4R3J6|S4R3J6_HUMAN,tr|F8WB06|F8WB06_HUMAN,tr|V9GY86|V9GY86_HUMAN,tr|A0A2R8Y7E6|A0A2R8Y7E6_HUMAN,tr|A0A5F9ZHX3|A0A5F9ZHX3_HUMAN,tr|H0YH87|H0YH87_HUMAN,tr|A0A2R8Y7P6|A0A2R8Y7P6_HUMAN" 18 971.54 1.62 109569 2997 2 971.537337 486.7773 Ataxin-2-like protein OS=Homo sapiens OX=9606 GN=ATXN2L PE=1 SV=2 10 1246.9 - 1.01E+06 - - - -2.7348 - 2.319 0.432 - 399.8 1 2 0 -0.0027 9 0 0 0 4.97E+07 3.07E+07 - - - 4.6644 0.9978 221125_WJC_METTL3_EV_vs_WT_F08.02998.02998.2 0.0876 14-Sep R.KLTPQGQR.D "sp|P39019|RS19_HUMAN,tr|A0A075B6E2|A0A075B6E2_HUMAN" 2 926.5298 1.1 109570 2998 2 926.527053 464.2722 40S ribosomal protein S19 OS=Homo sapiens OX=9606 GN=RPS19 PE=1 SV=2 11 1247 - 2.16E+07 - - - -2.926 - 2.121 0.225 - 353.8 1 2 0 -0.0027 8 0 0 0 4.19E+09 3.81E+09 - - - 2.9697 0.9961 221125_WJC_METTL3_EV_vs_WT_F08.03001.03001.2 0.0503 16-Dec K.R[166.11]LQEETGAK[136.11].M "sp|Q5VWX1|KHDR2_HUMAN,sp|Q07666|KHDR1_HUMAN,tr|A0A6Q8PGH5|A0A6Q8PGH5_HUMAN" 3 1048.5632 1 109571 3001 2 1048.558942 525.2889 "KH domain-containing, RNA-binding, signal transduction-associated protein 2 OS=Homo sapiens OX=9606 GN=KHDRBS2 PE=1 SV=1" 6.14 1247.4 - 796378 - - - -4.0541 - 2.218 0.258 - 421.4 1 2 0 -0.0043 9 0 0 0 8.23E+07 8.22E+07 - - - 3.2499 0.9986 221125_WJC_METTL3_EV_vs_WT_F08.03003.03003.2 0.00197 18-Oct R.AGQEVESGQK.K "sp|Q14690|RRP5_HUMAN,tr|A0A3B3IUD7|A0A3B3IUD7_HUMAN" 2 1031.4884 0.29 109573 3003 2 1031.484638 516.7515 Protein RRP5 homolog OS=Homo sapiens OX=9606 GN=PDCD11 PE=1 SV=3 4.53 1247.6 - 983051 - - - -3.6016 - 2.116 0.398 - 451.9 1 2 0 -0.0037 10 0 0 0 2.29E+07 7.83E+07 - - - 4.0716 0.9926 221125_WJC_METTL3_EV_vs_WT_F08.03008.03008.2 0.0515 16-Oct K.RLQEETGAK.M "sp|Q5VWX1|KHDR2_HUMAN,sp|Q07666|KHDR1_HUMAN,tr|A0A6Q8PGH5|A0A6Q8PGH5_HUMAN" 3 1030.5407 1 109576 3008 2 1030.536827 516.2776 "KH domain-containing, RNA-binding, signal transduction-associated protein 2 OS=Homo sapiens OX=9606 GN=KHDRBS2 PE=1 SV=1" 6.14 1248.2 - 1.41E+06 - - - -3.7805 - 1.871 0.214 - 339.7 1 2 0 -0.0039 9 0 0 0 8.23E+07 8.22E+07 - - - 2.4328 0.9994 221125_WJC_METTL3_EV_vs_WT_F08.03010.03010.2 0.00289 16-Sep K.SEAPSGESR.K "sp|Q99613|EIF3C_HUMAN,sp|B5ME19|EIFCL_HUMAN" 2 918.4043 0.8 109578 3010 2 918.401716 460.2094 Eukaryotic translation initiation factor 3 subunit C OS=Homo sapiens OX=9606 GN=EIF3C PE=1 SV=1 4.53 1248.5 - 2.22E+06 - - - -2.8016 - 1.819 0.484 - 340.9 1 2 0 -0.0026 9 0 0 0 4.55E+07 5.67E+07 - - - 4.3459 0.8882 221125_WJC_METTL3_EV_vs_WT_F08.03019.03019.2 8.42 12-Jul R.QRPSEIK.D sp|P08779|K1C16_HUMAN 1 856.4767 466.95 109583 3019 2 856.47327 429.2456 "Keratin, type I cytoskeletal 16 OS=Homo sapiens OX=9606 GN=KRT16 PE=1 SV=4" 8.75 1249.5 - 4.12E+06 - - - -3.9651 - 1.391 0.044 - 258.6 1 2 0 -0.0034 7 0 0 0 2.02E+08 4.33E+05 - - - 0.4106 0.9594 221125_WJC_METTL3_EV_vs_WT_F08.03027.03027.2 2.58 12-Jun K.KSYTTPK.K "sp|P62979|RS27A_HUMAN,tr|J3QTR3|J3QTR3_HUMAN" 2 823.444 0.56 109586 3027 2 823.443159 412.7293 Ubiquitin-40S ribosomal protein S27a OS=Homo sapiens OX=9606 GN=RPS27A PE=1 SV=2 9.7 1250.5 - 857292 - - - -0.9837 - 1.133 0.079 - 122.4 3 2 0 -0.0008 7 0 0 0 2.52E+07 4.49E+07 - - - -0.1932 0.9887 221125_WJC_METTL3_EV_vs_WT_F08.03033.03033.2 0.0162 18-Jul R.SAVPPGADK[136.11]K[136.11].A "sp|P46783|RS10_HUMAN,tr|F6U211|F6U211_HUMAN,tr|A0A1W2PQS6|A0A1W2PQS6_HUMAN,tr|A0A2R8YFH6|A0A2R8YFH6_HUMAN,tr|A0A2R8Y7H1|A0A2R8Y7H1_HUMAN,tr|S4R435|S4R435_HUMAN" 6 984.5575 1.26 109590 3033 2 984.553332 493.286 40S ribosomal protein S10 OS=Homo sapiens OX=9606 GN=RPS10 PE=1 SV=1 8.31 1251.2 - 1.44E+06 - - - -4.2283 - 1.484 0.297 - 191.9 1 2 0 -0.0042 10 0 0 0 3.62E+08 2.87E+08 - - - 2.3352 0.9996 221125_WJC_METTL3_EV_vs_WT_F08.03038.03038.2 0.000899 14-Sep K.C[160.03]NAEEHVR.V sp|P11279|LAMP1_HUMAN 1 1013.4349 3.03 109593 3038 2 1013.432098 507.7247 Lysosome-associated membrane glycoprotein 1 OS=Homo sapiens OX=9606 GN=LAMP1 PE=1 SV=3 5.4 1251.9 - 1.12E+06 - - - -2.7431 - 2.072 0.529 - 461.4 1 2 0 -0.0028 8 0 0 0 2.73E+07 9.01E+06 - - - 5.1445 0.9998 221125_WJC_METTL3_EV_vs_WT_F08.03050.03050.3 0.000301 15/32 R.C[160.03]IHSEEGC[160.03]R.W "sp|Q9BUZ4|TRAF4_HUMAN,tr|A0A0C4DFM9|A0A0C4DFM9_HUMAN,tr|F6SA91|F6SA91_HUMAN,tr|C9JJ10|C9JJ10_HUMAN,tr|J9JIG0|J9JIG0_HUMAN" 5 1146.4546 2.97 109601 3050 3 1146.449921 383.1588 TNF receptor-associated factor 4 OS=Homo sapiens OX=9606 GN=TRAF4 PE=1 SV=1 5.4 1253.4 - 780684 - - - -4.1048 - 2.22 0.521 - 348.3 1 2 0 -0.0047 9 0 0 0 1.24E+07 4.20E+06 - - - 6.7509 0.9685 221125_WJC_METTL3_EV_vs_WT_F08.03055.03055.2 0.209 16-Jul R.QEARPEPAR.L "sp|P55265|DSRAD_HUMAN,tr|A0A3B3ITG9|A0A3B3ITG9_HUMAN,tr|A0A3B3IRQ9|A0A3B3IRQ9_HUMAN,tr|A0A3B3ISU1|A0A3B3ISU1_HUMAN,tr|A0A7P0Z4K3|A0A7P0Z4K3_HUMAN,tr|A0A7P0TA14|A0A7P0TA14_HUMAN,tr|A0A3B3ISX1|A0A3B3ISX1_HUMAN,tr|A0A7P0Z4F9|A0A7P0Z4F9_HUMAN" 8 1052.5363 0.92 109604 3055 2 1052.532135 527.2754 Double-stranded RNA-specific adenosine deaminase OS=Homo sapiens OX=9606 GN=ADAR PE=1 SV=4 6.14 1254 - 1.22E+06 - - - -3.9628 - 1.392 0.183 - 87.5 1 2 0 -0.0042 9 0 0 0 2.51E+07 2.72E+07 - - - 1.3482 0.8159 221125_WJC_METTL3_EV_vs_WT_F08.03056.03056.3 1.77 Oct-36 K.VMQEQGTHPK.F sp|P35579|MYH9_HUMAN 1 1153.555 0.93 109605 3056 3 1153.550442 385.5256 Myosin-9 OS=Homo sapiens OX=9606 GN=MYH9 PE=1 SV=4 6.72 1254.1 - 1.57E+06 - - - -3.9452 - 1.662 0.103 - 168.5 1 2 0 -0.0046 10 0 0 0 1.00E+08 1.08E+08 - - - 1.1707 0.9985 221125_WJC_METTL3_EV_vs_WT_F08.03063.03063.2 3.74E-05 18-Oct K.VMQEQGTHPK[136.11].F sp|P35579|MYH9_HUMAN 1 1161.5692 0.9 109610 3063 2 1161.565394 581.7919 Myosin-9 OS=Homo sapiens OX=9606 GN=MYH9 PE=1 SV=4 6.72 1254.9 - 930246 - - - -3.2706 - 2.159 0.339 - 351.4 1 2 0 -0.0038 10 0 0 0 1.90E+07 2.10E+07 - - - 3.692 0.988 221125_WJC_METTL3_EV_vs_WT_F08.03064.03064.2 0.00111 12-Aug K.C[160.03]DLTTKK.V "sp|P62820|RAB1A_HUMAN,tr|E7END7|E7END7_HUMAN" 2 864.4375 0.34 109611 3064 2 864.434617 433.226 Ras-related protein Rab-1A OS=Homo sapiens OX=9606 GN=RAB1A PE=1 SV=3 8.2 1255.1 - 504532 - - - -3.3386 - 1.692 0.141 - 252.5 1 2 0 -0.0029 7 0 0 0 6.45E+06 1.87E+07 - - - 1.7479 0.999 221125_WJC_METTL3_EV_vs_WT_F08.03068.03068.2 0.0281 18-Oct K.VMQEQGTHPK.F sp|P35579|MYH9_HUMAN 1 1153.555 0.9 109613 3068 2 1153.551535 577.7848 Myosin-9 OS=Homo sapiens OX=9606 GN=MYH9 PE=1 SV=4 6.72 1255.6 - 1.34E+06 - - - -2.9977 - 2.042 0.401 - 386.1 1 2 0 -0.0035 10 0 0 0 1.90E+07 2.10E+07 - - - 3.9945 0.9982 221125_WJC_METTL3_EV_vs_WT_F08.03069.03069.2 0.00758 18-Sep K.LQGATC[160.03]NNNK.L "sp|Q14204|DYHC1_HUMAN,tr|A0A7P0T9C4|A0A7P0T9C4_HUMAN,tr|A0A2R8Y706|A0A2R8Y706_HUMAN,tr|A0A7P0TA13|A0A7P0TA13_HUMAN,tr|A0A2R8Y5T0|A0A2R8Y5T0_HUMAN" 5 1118.5139 0.87 109614 3069 2 1118.509915 560.2642 Cytoplasmic dynein 1 heavy chain 1 OS=Homo sapiens OX=9606 GN=DYNC1H1 PE=1 SV=5 8.22 1255.6 - 3.04E+06 - - - -3.5234 - 1.805 0.402 - 206 1 2 0 -0.0039 10 0 0 0 2.84E+07 3.28E+07 - - - 3.6574 0.8669 221125_WJC_METTL3_EV_vs_WT_F08.03076.03076.2 0.00134 18-Oct K.LR[166.11]EQQAADAK[136.11].K "sp|Q8N6H7|ARFG2_HUMAN,tr|E9PIY6|E9PIY6_HUMAN,tr|E9PQP3|E9PQP3_HUMAN,tr|G5E9L0|G5E9L0_HUMAN,tr|A0A0D9SF70|A0A0D9SF70_HUMAN" 5 1146.6112 1.19 109621 3076 2 1146.604432 574.3129 ADP-ribosylation factor GTPase-activating protein 2 OS=Homo sapiens OX=9606 GN=ARFGAP2 PE=1 SV=1 6.07 1256.4 - 486010 - - - -5.9078 - 1.943 0.329 - 302.3 1 2 1 -0.0068 10 0 0 0 2.26E+07 1.90E+07 - - - 3.3229 0.9997 221125_WJC_METTL3_EV_vs_WT_F08.03079.03079.2 1.04E-05 18-Dec K.TASDQATTAR[166.11].L "sp|O60573|IF4E2_HUMAN,tr|B4E1E4|B4E1E4_HUMAN,tr|B9A044|B9A044_HUMAN,tr|B8ZZL3|B8ZZL3_HUMAN,tr|B9A023|B9A023_HUMAN,tr|B8ZZ50|B8ZZ50_HUMAN,tr|C9JEL3|C9JEL3_HUMAN" 7 1030.4919 2.06 109622 3079 2 1030.48966 516.2532 Eukaryotic translation initiation factor 4E type 2 OS=Homo sapiens OX=9606 GN=EIF4E2 PE=1 SV=1 5.5 1256.8 - 3.32E+06 - - - -2.1465 - 2.187 0.492 - 514.6 1 2 0 -0.0022 10 0 0 0 7.08E+07 3.44E+07 - - - 4.8585 0.9994 221125_WJC_METTL3_EV_vs_WT_F08.03081.03081.2 0.000736 16-Sep R.KLEEDDQAK.D "sp|O95619|YETS4_HUMAN,tr|F8W0J4|F8W0J4_HUMAN" 2 1074.5193 1.26 109624 3081 2 1074.516354 538.2669 YEATS domain-containing protein 4 OS=Homo sapiens OX=9606 GN=YEATS4 PE=1 SV=1 4.32 1256.9 - 1.60E+06 - - - -2.7594 - 1.891 0.468 - 289.6 1 2 0 -0.003 9 0 0 0 1.33E+07 1.06E+07 - - - 4.3399 0.9867 221125_WJC_METTL3_EV_vs_WT_F08.03085.03085.2 0.0412 14-Aug K.SNLQNC[160.03]SK.F "sp|Q15054|DPOD3_HUMAN,tr|E9PRK3|E9PRK3_HUMAN,tr|E9PNC0|E9PNC0_HUMAN,tr|E9PM91|E9PM91_HUMAN" 4 949.4287 0.09 109628 3085 2 949.426833 475.7216 DNA polymerase delta subunit 3 OS=Homo sapiens OX=9606 GN=POLD3 PE=1 SV=2 7.94 1257.3 - 589444 - - - -1.998 - 1.339 0.139 - 208.9 1 2 0 -0.0019 8 0 0 0 7.59E+06 8.05E+07 - - - 0.9475 0.9941 221125_WJC_METTL3_EV_vs_WT_F08.03090.03090.2 0.00975 13/18 K.LREQQAADAK.K "sp|Q8N6H7|ARFG2_HUMAN,tr|E9PIY6|E9PIY6_HUMAN,tr|E9PQP3|E9PQP3_HUMAN,tr|G5E9L0|G5E9L0_HUMAN,tr|A0A0D9SF70|A0A0D9SF70_HUMAN" 5 1128.5887 1.17 109631 3090 2 1128.585786 565.3016 ADP-ribosylation factor GTPase-activating protein 2 OS=Homo sapiens OX=9606 GN=ARFGAP2 PE=1 SV=1 6.07 1258 - 2.55E+06 - - - -2.6139 - 2.358 0.405 - 717.3 1 2 1 -0.0029 10 0 0 0 2.22E+07 1.90E+07 - - - 4.4258 0.8576 221125_WJC_METTL3_EV_vs_WT_F08.03092.03092.2 2.06 14-May K.KSASETVK.G sp|D6RIA3|CD054_HUMAN 1 848.4603 999 109633 3092 2 848.457915 425.2374 Uncharacterized protein C4orf54 OS=Homo sapiens OX=9606 GN=C4orf54 PE=2 SV=1 8.59 1258.1 - 1.15E+06 - - - -2.8664 - 1.065 0.095 - 85.9 3 2 0 -0.0024 8 0 0 0 2.27E+07 0.00E+00 - - - -0.2813 0.9044 221125_WJC_METTL3_EV_vs_WT_F08.03096.03096.2 0.000411 16-Oct K.EEEEEEASK.V sp|Q16352|AINX_HUMAN 1 1078.4302 0.56 109637 3096 2 1078.422369 540.2224 Alpha-internexin OS=Homo sapiens OX=9606 GN=INA PE=1 SV=2 3.9 1258.7 - 450213 - - - -7.2884 - 1.822 0.198 - 425.9 1 2 0 -0.0079 9 0 0 0 3.40E+06 6.10E+06 - - - 2.2366 0.9991 221125_WJC_METTL3_EV_vs_WT_F08.03100.03100.2 0.00386 16-Aug K.SSSQEVEAK.E sp|Q8IWA0|WDR75_HUMAN 1 963.4509 1.28 109639 3100 2 963.449339 482.7327 WD repeat-containing protein 75 OS=Homo sapiens OX=9606 GN=WDR75 PE=1 SV=1 4.53 1259.2 - 1.72E+06 - - - -1.6254 - 1.568 0.361 - 262 1 2 0 -0.0016 9 0 0 0 2.03E+07 1.58E+07 - - - 3.0082 0.819 221125_WJC_METTL3_EV_vs_WT_F08.03106.03106.2 0.136 12-Aug T.TVTPDK[136.11]R[166.11].K "sp|Q16186|ADRM1_HUMAN,tr|A0A087WUX6|A0A087WUX6_HUMAN,tr|A0A087WX59|A0A087WX59_HUMAN" 3 833.4726 2.22 109643 3106 2 833.471509 417.7436 Proteasomal ubiquitin receptor ADRM1 OS=Homo sapiens OX=9606 GN=ADRM1 PE=1 SV=2 8.41 1259.9 - 622385 - - - -1.2934 - 1.371 0.207 - 294 1 1 0 -0.0011 7 0 0 0 1.26E+07 5.69E+06 - - - 1.5694 0.9982 221125_WJC_METTL3_EV_vs_WT_F08.03108.03108.2 0.0237 12-Sep R.HEQVVER[166.11].L "sp|Q8NBT2|SPC24_HUMAN,tr|K7ERQ7|K7ERQ7_HUMAN,tr|K7EJH0|K7EJH0_HUMAN,tr|K7EMX1|K7EMX1_HUMAN,tr|K7EJV2|K7EJV2_HUMAN,tr|A0A0A0MSN0|A0A0A0MSN0_HUMAN,tr|K7ESQ2|K7ESQ2_HUMAN" 7 905.4594 2.14 109645 3108 2 905.457796 453.737 Kinetochore protein Spc24 OS=Homo sapiens OX=9606 GN=SPC24 PE=1 SV=2 5.4 1260.2 - 507213 - - - -1.8256 - 1.672 0.235 - 257.8 1 2 0 -0.0017 7 0 0 0 6.61E+07 3.09E+07 - - - 2.4049 0.9924 221125_WJC_METTL3_EV_vs_WT_F08.03110.03110.2 0.0862 16-Sep K.LK[136.11]NVQSETK[136.11].G "sp|Q14527|HLTF_HUMAN,tr|A0A0C4DGA6|A0A0C4DGA6_HUMAN" 2 1061.6052 1.28 109647 3110 2 1061.603217 531.8099 Helicase-like transcription factor OS=Homo sapiens OX=9606 GN=HLTF PE=1 SV=2 8.59 1260.4 - 268867 - - - -1.8434 - 1.979 0.322 - 213.4 1 2 1 -0.002 9 0 0 0 1.04E+07 8.11E+06 - - - 3.3935 0.9776 221125_WJC_METTL3_EV_vs_WT_F08.03115.03115.2 5.03E-05 18-Oct Q.SVGGDSSADR[166.11].L "sp|Q86U44|MTA70_HUMAN,tr|H0YFV6|H0YFV6_HUMAN" 2 959.4184 1.07 109650 3115 2 959.415652 480.7165 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 4.21 1261 - 8.24E+06 - - - -2.8351 - 2.195 0.551 - 202.7 1 1 0 -0.0027 10 0 0 0 2.52E+08 2.35E+08 - - - 5.3043 0.991 221125_WJC_METTL3_EV_vs_WT_F08.03118.03118.2 0.000821 16-Sep K.LKNVQSETK.G "sp|Q14527|HLTF_HUMAN,tr|A0A0C4DGA6|A0A0C4DGA6_HUMAN" 2 1045.5768 1.28 109653 3118 2 1045.574353 523.7957 Helicase-like transcription factor OS=Homo sapiens OX=9606 GN=HLTF PE=1 SV=2 8.59 1261.3 - 656989 - - - -2.3155 - 1.912 0.361 - 204 1 2 1 -0.0024 9 0 0 0 1.04E+07 8.11E+06 - - - 3.5817 0.9965 221125_WJC_METTL3_EV_vs_WT_F08.03128.03128.2 0.000109 16-Aug R.GGSGGSYGR.G "sp|P35527|K1C9_HUMAN,tr|K7EQQ3|K7EQQ3_HUMAN" 2 796.3464 121.84 109660 3128 2 796.34474 399.1805 "Keratin, type I cytoskeletal 9 OS=Homo sapiens OX=9606 GN=KRT9 PE=1 SV=3" 8.75 1262.4 - 8.21E+06 - - - -2.0594 - 1.573 0.222 - 429.7 1 2 0 -0.0016 9 0 0 0 5.47E+07 4.49E+05 - - - 1.9907 0.9981 221125_WJC_METTL3_EV_vs_WT_F08.03134.03134.2 0.0528 16-Jul R.MTQQQENPK[136.11].F sp|Q13045|FLII_HUMAN 1 1110.5219 1.2 109666 3134 2 1110.520515 556.2682 Protein flightless-1 homolog OS=Homo sapiens OX=9606 GN=FLII PE=1 SV=2 5.75 1262.9 - 514285 - - - -1.2544 - 1.389 0.282 - 124.2 1 2 0 -0.0014 9 0 0 0 1.33E+07 1.11E+07 - - - 2.074 0.9998 221125_WJC_METTL3_EV_vs_WT_F08.03135.03135.2 2.66E-05 16-Sep R.MTQQQENPK.F sp|Q13045|FLII_HUMAN 1 1102.5077 0.68 109667 3135 2 1102.506493 552.2611 Protein flightless-1 homolog OS=Homo sapiens OX=9606 GN=FLII PE=1 SV=2 5.75 1263.1 - 477117 - - - -1.102 - 1.785 0.471 - 306.7 1 2 0 -0.0012 9 0 0 0 6.34E+06 9.34E+06 - - - 4.1957 0.9992 221125_WJC_METTL3_EV_vs_WT_F08.03138.03138.2 0.000685 18-Aug K.AC[160.03]TTEEDQEK[136.11].L sp|P49915|GUAA_HUMAN 1 1217.4961 0.88 109670 3138 2 1217.492351 609.7553 GMP synthase [glutamine-hydrolyzing] OS=Homo sapiens OX=9606 GN=GMPS PE=1 SV=1 4 1263.4 - 107497 - - - -3.1179 - 1.36 0.6 - 206 1 2 0 -0.0038 10 0 0 0 5.80E+06 6.56E+06 - - - 4.3297 0.999 221125_WJC_METTL3_EV_vs_WT_F08.03140.03140.2 3.14 16-Oct K.TPSSSQPER[166.11].L sp|O43395|PRPF3_HUMAN 1 997.4704 1.97 109671 3140 2 997.467779 499.7425 U4\U6 small nuclear ribonucleoprotein Prp3 OS=Homo sapiens OX=9606 GN=PRPF3 PE=1 SV=2 5.66 1263.7 - 1.30E+07 - - - -2.6357 - 2.089 0.332 - 365.7 1 2 0 -0.0026 9 0 0 0 5.83E+08 2.97E+08 - - - 3.6236 0.9989 221125_WJC_METTL3_EV_vs_WT_F08.03142.03142.2 0.0309 14-Jul K.SC[160.03]QVENGR.V "sp|Q9NR56|MBNL1_HUMAN,sp|Q5VZF2|MBNL2_HUMAN,tr|H7C4T5|H7C4T5_HUMAN,tr|A0A0A0MQX8|A0A0A0MQX8_HUMAN,tr|A0A7P0T9I3|A0A7P0T9I3_HUMAN,tr|C9JP00|C9JP00_HUMAN,tr|O95205|O95205_HUMAN" 7 948.4083 1.39 109673 3142 2 948.405694 475.2114 Muscleblind-like protein 1 OS=Homo sapiens OX=9606 GN=MBNL1 PE=1 SV=2 5.72 1263.8 - 7.85E+06 - - - -2.7783 - 1.707 0.405 - 227.2 1 2 0 -0.0026 8 0 0 0 5.82E+08 4.20E+08 - - - 3.6442 0.9952 221125_WJC_METTL3_EV_vs_WT_F08.03146.03146.2 0.00762 12-Sep R.HQFGQEK[136.11].D "sp|Q9UPN6|SCAF8_HUMAN,tr|A0A0A0MT33|A0A0A0MT33_HUMAN" 2 880.4283 0.82 109677 3146 2 880.425375 441.2214 SR-related and CTD-associated factor 8 OS=Homo sapiens OX=9606 GN=SCAF8 PE=1 SV=1 6.75 1264.1 - 1.15E+06 - - - -3.2836 - 1.627 0.259 - 251.2 1 2 0 -0.0029 7 0 0 0 9.03E+06 1.09E+07 - - - 2.4953 0.9926 221125_WJC_METTL3_EV_vs_WT_F08.03147.03147.2 0.202 12-Jun R.HQFGQEK.D "sp|Q9UPN6|SCAF8_HUMAN,tr|A0A0A0MT33|A0A0A0MT33_HUMAN" 2 872.4141 0.83 109678 3147 2 872.412435 437.2143 SR-related and CTD-associated factor 8 OS=Homo sapiens OX=9606 GN=SCAF8 PE=1 SV=1 6.75 1264.1 - 976155 - - - -1.8695 - 1.429 0.154 - 103.6 1 2 0 -0.0016 7 0 0 0 9.08E+06 1.09E+07 - - - 1.309 0.999 221125_WJC_METTL3_EV_vs_WT_F08.03150.03150.3 0.00566 Aug-36 R.AEVGEK[136.11]TEER[166.11].R "sp|P42167|LAP2B_HUMAN,tr|G5E972|G5E972_HUMAN,tr|H0YJH7|H0YJH7_HUMAN" 3 1164.5742 4.63 109681 3150 3 1164.573043 389.1987 "Lamina-associated polypeptide 2, isoforms beta\gamma OS=Homo sapiens OX=9606 GN=TMPO PE=1 SV=2" 4.49 1264.4 - 443309 - - - -0.9514 - 2.063 0.346 - 98.2 1 2 1 -0.0011 10 0 0 0 6.45E+07 1.39E+07 - - - 4.5121 0.999 221125_WJC_METTL3_EV_vs_WT_F08.03154.03154.2 9.45E-05 14-Aug K.SC[160.03]QVENGR[166.11].V "sp|Q9NR56|MBNL1_HUMAN,sp|Q5VZF2|MBNL2_HUMAN,tr|H7C4T5|H7C4T5_HUMAN,tr|A0A0A0MQX8|A0A0A0MQX8_HUMAN,tr|A0A7P0T9I3|A0A7P0T9I3_HUMAN,tr|C9JP00|C9JP00_HUMAN,tr|O95205|O95205_HUMAN" 7 958.4166 1.37 109683 3154 2 958.413837 480.2156 Muscleblind-like protein 1 OS=Homo sapiens OX=9606 GN=MBNL1 PE=1 SV=2 5.72 1264.9 - 2.01E+07 - - - -2.8818 - 1.633 0.456 - 297.1 1 2 0 -0.0028 8 0 0 0 5.83E+08 4.26E+08 - - - 3.8872 0.9996 221125_WJC_METTL3_EV_vs_WT_F08.03155.03155.3 1.38E-06 14/40 R.VGEGDKEDATR.R sp|Q8WXX5|DNJC9_HUMAN 1 1175.5418 1.45 109684 3155 3 1175.537752 392.8546 DnaJ homolog subfamily C member 9 OS=Homo sapiens OX=9606 GN=DNAJC9 PE=1 SV=1 4.32 1265 - 2.09E+06 - - - -3.4818 - 2.636 0.56 - 414.4 1 2 1 -0.0041 11 0 0 0 1.53E+07 1.06E+07 - - - 7.5358 0.9999 221125_WJC_METTL3_EV_vs_WT_F08.03160.03160.2 1.88E-05 18-Aug K.AC[160.03]TTEEDQEK.L sp|P49915|GUAA_HUMAN 1 1209.4819 0.88 109688 3160 2 1209.482886 605.7482 GMP synthase [glutamine-hydrolyzing] OS=Homo sapiens OX=9606 GN=GMPS PE=1 SV=1 4 1265.5 - 426208 - - - 0.7764 - 1.761 0.601 - 157.5 1 2 0 0.0009 10 0 0 0 5.80E+06 6.56E+06 - - - 5.0592 0.9998 221125_WJC_METTL3_EV_vs_WT_F08.03166.03166.3 0.00161 13/36 R.AEVGEKTEER.R "sp|P42167|LAP2B_HUMAN,tr|G5E972|G5E972_HUMAN,tr|H0YJH7|H0YJH7_HUMAN" 3 1146.5517 4.43 109692 3166 3 1146.55026 383.1912 "Lamina-associated polypeptide 2, isoforms beta\gamma OS=Homo sapiens OX=9606 GN=TMPO PE=1 SV=2" 4.49 1266.1 - 2.75E+06 - - - -1.2394 - 2.512 0.427 - 408.6 1 2 1 -0.0014 10 0 0 0 6.54E+07 1.48E+07 - - - 5.9902 0.9184 221125_WJC_METTL3_EV_vs_WT_F08.03168.03168.2 0.548 14-Jun R.NLSNPAK[136.11]K[136.11].F sp|O43395|PRPF3_HUMAN 1 886.5207 2.23 109694 3168 2 886.517194 444.2676 U4\U6 small nuclear ribonucleoprotein Prp3 OS=Homo sapiens OX=9606 GN=PRPF3 PE=1 SV=2 10 1266.4 - 499622 - - - -3.9728 - 1.151 0.16 - 108.4 1 2 0 -0.0035 8 0 0 0 1.32E+08 5.92E+07 - - - 0.6458 0.9962 221125_WJC_METTL3_EV_vs_WT_F08.03172.03172.2 0.0108 12-Sep R.RQQEGFK.G "sp|Q15233|NONO_HUMAN,sp|Q8WXF1|PSPC1_HUMAN,tr|A0A7I2V535|A0A7I2V535_HUMAN,tr|A0A0U1RQF9|A0A0U1RQF9_HUMAN,tr|A0A7I2V4K9|A0A7I2V4K9_HUMAN,tr|A0A7P0MRW0|A0A7P0MRW0_HUMAN,tr|H7C367|H7C367_HUMAN,tr|A0A7I2V4J2|A0A7I2V4J2_HUMAN,tr|A0A7I2V5Y7|A0A7I2V5Y7_HUMAN" 9 891.4563 0.73 109696 3172 2 891.45308 446.7354 Non-POU domain-containing octamer-binding protein OS=Homo sapiens OX=9606 GN=NONO PE=1 SV=4 8.75 1266.8 - 5.73E+06 - - - -3.5728 - 1.665 0.305 - 435.8 1 2 0 -0.0032 7 0 0 0 8.82E+07 1.21E+08 - - - 2.9081 0.9886 221125_WJC_METTL3_EV_vs_WT_F08.03174.03174.2 0.0148 12-Sep R.R[166.11]QQEGFK[136.11].G "sp|Q15233|NONO_HUMAN,sp|Q8WXF1|PSPC1_HUMAN,tr|A0A7I2V535|A0A7I2V535_HUMAN,tr|A0A0U1RQF9|A0A0U1RQF9_HUMAN,tr|A0A7I2V4K9|A0A7I2V4K9_HUMAN,tr|A0A7P0MRW0|A0A7P0MRW0_HUMAN,tr|H7C367|H7C367_HUMAN,tr|A0A7I2V4J2|A0A7I2V4J2_HUMAN,tr|A0A7I2V5Y7|A0A7I2V5Y7_HUMAN" 9 909.4787 0.73 109698 3174 2 909.475358 455.7466 Non-POU domain-containing octamer-binding protein OS=Homo sapiens OX=9606 GN=NONO PE=1 SV=4 8.75 1266.9 - 9.94E+06 - - - -3.7131 - 1.781 0.155 - 464.1 1 2 0 -0.0034 7 0 0 0 8.83E+07 1.21E+08 - - - 2.0136 0.9529 221125_WJC_METTL3_EV_vs_WT_F08.03175.03175.2 0.00053 18-Jul K.QAQNPDQGPK[136.11].L "sp|Q9NVZ3|NECP2_HUMAN,tr|D6RB24|D6RB24_HUMAN,tr|F6SKB8|F6SKB8_HUMAN" 3 1089.5294 0.21 109699 3175 2 1089.520613 545.772 Adaptin ear-binding coat-associated protein 2 OS=Homo sapiens OX=9606 GN=NECAP2 PE=1 SV=1 5.84 1267.1 - 825052 - - - -8.098 - 1.539 0.421 - 170 1 2 0 -0.0088 10 0 0 0 6.12E+06 2.91E+07 - - - 3.3512 0.9968 221125_WJC_METTL3_EV_vs_WT_F08.03181.03181.2 0.00206 16-Sep K.R[166.11]GVAC[160.03]TQPR[166.11].R sp|O43143|DHX15_HUMAN 1 1063.546 0.97 109701 3181 2 1063.541856 532.7803 Pre-mRNA-splicing factor ATP-dependent RNA helicase DHX15 OS=Homo sapiens OX=9606 GN=DHX15 PE=1 SV=2 10.35 1267.9 - 1.42E+06 - - - -3.8842 - 1.625 0.392 - 102.4 1 2 0 -0.0041 9 0 0 0 8.22E+07 8.49E+07 - - - 3.3396 0.9639 221125_WJC_METTL3_EV_vs_WT_F08.03184.03184.2 0.153 14-Jun R.RYNGGVGR.C "sp|P18621|RL17_HUMAN,tr|A0A087WWH0|A0A087WWH0_HUMAN,tr|J3QS96|J3QS96_HUMAN,tr|J3QLC8|J3QLC8_HUMAN,tr|J3QQT2|J3QQT2_HUMAN,tr|A0A087WY81|A0A087WY81_HUMAN,tr|A0A0A0MRF8|A0A0A0MRF8_HUMAN,tr|J3KRB3|J3KRB3_HUMAN,tr|J3KRX5|J3KRX5_HUMAN,tr|A0A087WXM6|A0A087WXM6_HUMAN,tr|A0A0A6YYL6|A0A0A6YYL6_HUMAN" 11 877.4518 0.97 109704 3184 2 877.449489 439.7332 60S ribosomal protein L17 OS=Homo sapiens OX=9606 GN=RPL17 PE=1 SV=3 10.84 1268.3 - 474306 - - - -2.6885 - 1.179 0.161 - 72.7 2 2 0 -0.0024 8 0 0 0 1.07E+07 1.10E+07 - - - 0.5916 0.8233 221125_WJC_METTL3_EV_vs_WT_F08.03186.03186.2 3.04 14-Jul R.AEEREQIK.T "sp|P48668|K2C6C_HUMAN,sp|P04259|K2C6B_HUMAN,sp|O95678|K2C75_HUMAN,sp|P02538|K2C6A_HUMAN" 4 1001.5142 231.82 109705 3186 2 1001.510797 501.7644 "Keratin, type II cytoskeletal 6C OS=Homo sapiens OX=9606 GN=KRT6C PE=1 SV=3" 4.79 1268.5 - 8.68E+06 - - - -3.3719 - 1.441 0.173 - 201.2 1 2 1 -0.0034 8 0 0 0 1.74E+08 7.50E+05 - - - 1.4196 0.9925 221125_WJC_METTL3_EV_vs_WT_F08.03188.03188.2 0.00108 16-Nov R.KSEEEVAAR.R "sp|P02788|TRFL_HUMAN,tr|E7EQB2|E7EQB2_HUMAN,tr|E7ER44|E7ER44_HUMAN" 3 1017.5091 2.12 109706 3188 2 1017.50568 509.7618 Lactotransferrin OS=Homo sapiens OX=9606 GN=LTF PE=1 SV=6 4.79 1268.7 - 4.97E+06 - - - -3.3494 - 2.025 0.144 - 439.5 1 2 0 -0.0034 9 0 0 0 7.11E+07 3.35E+07 - - - 2.1448 0.9948 221125_WJC_METTL3_EV_vs_WT_F08.03189.03189.2 0.0103 16-Jul R.NK[136.11]PSDLGTK[136.11].L "sp|P31948|STIP1_HUMAN,tr|F5H783|F5H783_HUMAN" 2 974.5368 0.74 109707 3189 2 974.535017 488.2757 Stress-induced-phosphoprotein 1 OS=Homo sapiens OX=9606 GN=STIP1 PE=1 SV=1 8.59 1268.8 - 2.66E+06 - - - -1.7885 - 1.429 0.198 - 127.9 1 2 0 -0.0017 9 0 0 0 4.44E+07 6.02E+07 - - - 1.5356 0.9856 221125_WJC_METTL3_EV_vs_WT_F08.03190.03190.2 0.00264 14-Sep R.QTIEEK[136.11]DR[166.11].S "sp|Q15643|TRIPB_HUMAN,tr|H0YJ97|H0YJ97_HUMAN" 2 1035.5316 2.12 109708 3190 2 1035.528429 518.7731 Thyroid receptor-interacting protein 11 OS=Homo sapiens OX=9606 GN=TRIP11 PE=1 SV=3 4.68 1268.8 - 2.50E+06 - - - -3.0216 - 1.884 0.363 - 457.2 1 2 1 -0.0031 8 0 0 0 7.11E+07 3.35E+07 - - - 3.6314 0.9959 221125_WJC_METTL3_EV_vs_WT_F08.03198.03198.2 0.0216 14-Aug R.R[166.11]YNGGVGR[166.11].C "sp|P18621|RL17_HUMAN,tr|A0A087WWH0|A0A087WWH0_HUMAN,tr|J3QS96|J3QS96_HUMAN,tr|J3QLC8|J3QLC8_HUMAN,tr|J3QQT2|J3QQT2_HUMAN,tr|A0A087WY81|A0A087WY81_HUMAN,tr|A0A0A0MRF8|A0A0A0MRF8_HUMAN,tr|J3KRB3|J3KRB3_HUMAN,tr|J3KRX5|J3KRX5_HUMAN,tr|A0A087WXM6|A0A087WXM6_HUMAN,tr|A0A0A6YYL6|A0A0A6YYL6_HUMAN" 11 897.4684 0.97 109714 3198 2 897.46524 449.7415 60S ribosomal protein L17 OS=Homo sapiens OX=9606 GN=RPL17 PE=1 SV=3 10.84 1269.7 - 931678 - - - -3.5076 - 1.564 0.326 - 124.4 1 2 0 -0.0031 8 0 0 0 1.07E+07 1.10E+07 - - - 2.7967 0.9997 221125_WJC_METTL3_EV_vs_WT_F08.03200.03200.2 0.000671 16-Sep K.YTTTSSSSR.K "sp|P48668|K2C6C_HUMAN,sp|P04259|K2C6B_HUMAN,sp|P02538|K2C6A_HUMAN" 3 988.4462 10061.23 109715 3200 2 988.444659 495.2304 "Keratin, type II cytoskeletal 6C OS=Homo sapiens OX=9606 GN=KRT6C PE=1 SV=3" 8.75 1269.9 - 9.60E+07 - - - -1.5125 - 1.807 0.48 - 311.1 1 2 0 -0.0015 9 0 0 0 7.72E+09 7.68E+05 - - - 4.2975 0.9995 221125_WJC_METTL3_EV_vs_WT_F08.03202.03202.2 0.318 13/16 K.RGVAC[160.03]TQPR.R sp|O43143|DHX15_HUMAN 1 1043.5294 0.97 109716 3202 2 1043.526493 522.772 Pre-mRNA-splicing factor ATP-dependent RNA helicase DHX15 OS=Homo sapiens OX=9606 GN=DHX15 PE=1 SV=2 10.35 1270.1 - 7.15E+06 - - - -2.8308 - 2.471 0.442 - 265.5 1 2 0 -0.003 9 0 0 0 8.22E+07 8.49E+07 - - - 4.9218 0.9764 221125_WJC_METTL3_EV_vs_WT_F08.03203.03203.2 0.766 16-Jun R.KGGPAPVDR[166.11].K "sp|O75081|MTG16_HUMAN,tr|H3BNI7|H3BNI7_HUMAN" 2 905.4958 - 109717 3203 2 905.494557 453.7552 Protein CBFA2T3 OS=Homo sapiens OX=9606 GN=CBFA2T3 PE=1 SV=2 8.75 1270.2 - 4.76E+06 - - - -1.4114 - 1.182 0.123 - 106.5 2 2 0 -0.0013 9 0 0 0 - - - - - 0.2983 0.9995 221125_WJC_METTL3_EV_vs_WT_F08.03214.03214.2 0.071 26-Oct R.GGAEAGGAASDGSR[166.11].G sp|Q8N9B5|JMY_HUMAN 1 1171.5093 2.09 109726 3214 2 1171.507222 586.7619 Junction-mediating and -regulatory protein OS=Homo sapiens OX=9606 GN=JMY PE=1 SV=2 4.37 1271.4 - 140884 - - - -1.7849 - 1.871 0.416 - 362.5 1 2 0 -0.0021 14 0 0 0 1.49E+06 7.12E+05 - - - 3.685 0.9994 221125_WJC_METTL3_EV_vs_WT_F08.03216.03216.2 0.0018 14-Oct R.NDLRPANK.L "sp|Q53F19|NCBP3_HUMAN,tr|K7EQA5|K7EQA5_HUMAN" 2 926.4934 1.26 109727 3216 2 926.491124 464.254 Nuclear cap-binding protein subunit 3 OS=Homo sapiens OX=9606 GN=NCBP3 PE=1 SV=2 8.75 1271.6 - 1.98E+06 - - - -2.4328 - 2.136 0.383 - 322.6 1 2 0 -0.0023 8 0 0 0 3.63E+07 2.88E+07 - - - 4.158 0.9993 221125_WJC_METTL3_EV_vs_WT_F08.03221.03221.2 0.0101 14-Jul K.KEPVETDR.L "sp|O75444|MAF_HUMAN,tr|H3BP11|H3BP11_HUMAN" 2 972.4876 3.38 109732 3221 2 972.486344 487.2511 Transcription factor Maf OS=Homo sapiens OX=9606 GN=MAF PE=1 SV=2 4.68 1272 - 1.39E+06 - - - -1.3162 - 1.645 0.327 - 233.5 1 2 0 -0.0013 8 0 0 0 2.56E+07 7.55E+06 - - - 2.957 0.9997 221125_WJC_METTL3_EV_vs_WT_F08.03222.03222.2 2.80E-05 18-Nov R.QVTDAETK[136.11]PK[136.11].S sp|O43684|BUB3_HUMAN 1 1131.6107 0.67 109733 3222 2 1131.608562 566.8126 Mitotic checkpoint protein BUB3 OS=Homo sapiens OX=9606 GN=BUB3 PE=1 SV=1 6.07 1272.1 - 606832 - - - -1.8478 - 2.073 0.479 - 527.7 1 2 0 -0.0021 10 0 0 0 2.37E+07 3.55E+07 - - - 4.6131 0.9991 221125_WJC_METTL3_EV_vs_WT_F08.03223.03223.2 0.00808 20-Jul K.AENTEGQGTPK[136.11].L sp|Q9NVM6|DJC17_HUMAN 1 1138.5346 1.24 109734 3223 2 1138.535039 570.2746 DnaJ homolog subfamily C member 17 OS=Homo sapiens OX=9606 GN=DNAJC17 PE=1 SV=1 4.53 1272.2 - 320722 - - - 0.4023 - 1.437 0.345 - 179.3 1 2 0 0.0005 11 0 0 0 6.60E+06 5.30E+06 - - - 2.5698 0.999 221125_WJC_METTL3_EV_vs_WT_F08.03227.03227.2 0.000505 18-Oct R.SGGGGYSQNR[166.11].W "sp|Q9BUJ2|HNRL1_HUMAN,tr|A0A0A0MRA5|A0A0A0MRA5_HUMAN,tr|M0R3F1|M0R3F1_HUMAN,tr|B7Z4B8|B7Z4B8_HUMAN" 4 991.4347 1.67 109736 3227 2 991.431764 496.7246 Heterogeneous nuclear ribonucleoprotein U-like protein 1 OS=Homo sapiens OX=9606 GN=HNRNPUL1 PE=1 SV=2 8.46 1272.7 - 2.21E+06 - - - -2.9523 - 2.417 0.325 - 391.6 1 2 0 -0.0029 10 0 0 0 1.64E+08 9.80E+07 - - - 3.9039 0.9997 221125_WJC_METTL3_EV_vs_WT_F08.03228.03228.2 0.000679 18-Sep R.QVTDAETKPK.S sp|O43684|BUB3_HUMAN 1 1115.5823 0.67 109737 3228 2 1115.581008 558.7984 Mitotic checkpoint protein BUB3 OS=Homo sapiens OX=9606 GN=BUB3 PE=1 SV=1 6.07 1272.9 - 778227 - - - -1.116 - 1.768 0.466 - 356.4 1 2 0 -0.0012 10 0 0 0 2.37E+07 3.55E+07 - - - 4.0731 0.8191 221125_WJC_METTL3_EV_vs_WT_F08.03229.03229.2 0.386 16-Jul R.EVNDAIYDK[136.11].L sp|Q9ULW6|NP1L2_HUMAN 1 1073.5121 0.09 109738 3229 2 1073.519404 537.7633 Nucleosome assembly protein 1-like 2 OS=Homo sapiens OX=9606 GN=NAP1L2 PE=1 SV=1 4.03 1273 - 770884 - - - 6.8458 - 1.275 0.222 - 130.5 1 2 0 0.0073 9 0 0 0 2.65E+06 2.91E+07 - - - 1.3812 0.9998 221125_WJC_METTL3_EV_vs_WT_F08.03239.03239.2 0.00622 18-Dec R.SGGGGYSQNR.W "sp|Q9BUJ2|HNRL1_HUMAN,tr|A0A0A0MRA5|A0A0A0MRA5_HUMAN,tr|M0R3F1|M0R3F1_HUMAN,tr|B7Z4B8|B7Z4B8_HUMAN" 4 981.4264 1.63 109746 3239 2 981.425752 491.7205 Heterogeneous nuclear ribonucleoprotein U-like protein 1 OS=Homo sapiens OX=9606 GN=HNRNPUL1 PE=1 SV=2 8.46 1274.3 - 8.06E+06 - - - -0.6817 - 2.556 0.385 - 637.3 1 2 0 -0.0007 10 0 0 0 1.59E+08 9.80E+07 - - - 4.5039 0.9987 221125_WJC_METTL3_EV_vs_WT_F08.03241.03241.2 0.429 12-Sep R.R[166.11]QTIEER[166.11].K sp|Q14152|EIF3A_HUMAN 1 950.5048 1.96 109748 3241 2 950.504312 476.2597 Eukaryotic translation initiation factor 3 subunit A OS=Homo sapiens OX=9606 GN=EIF3A PE=1 SV=1 6.14 1274.4 - 5.11E+06 - - - -0.5481 - 1.755 0.186 - 283.6 1 2 0 -0.0005 7 0 0 0 1.35E+08 6.88E+07 - - - 2.1968 0.9997 221125_WJC_METTL3_EV_vs_WT_F08.03242.03242.2 3.04E-05 16-Oct K.INHEGEVNR.A "sp|Q09028|RBBP4_HUMAN,sp|Q16576|RBBP7_HUMAN,tr|Q5JP01|Q5JP01_HUMAN,tr|E9PC52|E9PC52_HUMAN" 4 1066.5156 1.55 109749 3242 2 1066.51406 534.2651 Histone-binding protein RBBP4 OS=Homo sapiens OX=9606 GN=RBBP4 PE=1 SV=3 5.4 1274.5 - 4.14E+06 - - - -1.4168 - 1.843 0.429 - 445.3 1 2 0 -0.0015 9 0 0 0 4.58E+08 2.96E+08 - - - 3.9779 0.9997 221125_WJC_METTL3_EV_vs_WT_F08.03243.03243.2 0.000591 14-Aug R.TTNYNSSR.S "sp|Q86U42|PABP2_HUMAN,tr|B4DEH8|B4DEH8_HUMAN,tr|G3V4T2|G3V4T2_HUMAN,tr|H0YJH9|H0YJH9_HUMAN,tr|A0A7I2V383|A0A7I2V383_HUMAN" 5 941.4203 0.1 109750 3243 2 941.418796 471.7174 Polyadenylate-binding protein 2 OS=Homo sapiens OX=9606 GN=PABPN1 PE=1 SV=3 8.41 1274.5 - 2.12E+06 - - - -1.5689 - 1.619 0.474 - 310.8 1 2 0 -0.0015 8 0 0 0 1.90E+07 1.92E+08 - - - 3.9946 0.9787 221125_WJC_METTL3_EV_vs_WT_F08.03250.03250.2 0.00822 14-Jul L.NHEGEVNR.A "sp|Q09028|RBBP4_HUMAN,sp|Q16576|RBBP7_HUMAN,tr|Q5JP01|Q5JP01_HUMAN,tr|E9PC52|E9PC52_HUMAN" 4 953.4315 1.74 109755 3250 2 953.431865 477.723 Histone-binding protein RBBP4 OS=Homo sapiens OX=9606 GN=RBBP4 PE=1 SV=3 5.4 1275.3 - 4.73E+06 - - - 0.3755 - 1.554 0.413 - 275 1 1 0 0.0004 8 0 0 0 2.00E+08 1.15E+08 - - - 3.4208 0.994 221125_WJC_METTL3_EV_vs_WT_F08.03251.03251.2 0.0468 16-Sep R.AAKPEQIQK.W "sp|Q99986|VRK1_HUMAN,tr|A0A7P0T814|A0A7P0T814_HUMAN,tr|A0A7P0T838|A0A7P0T838_HUMAN,tr|H0YJJ9|H0YJJ9_HUMAN,tr|A0A7P0TA16|A0A7P0TA16_HUMAN,tr|A0A7P0T8N0|A0A7P0T8N0_HUMAN,tr|H0YJF7|H0YJF7_HUMAN,tr|A0A7P0T9T1|A0A7P0T9T1_HUMAN,tr|A0A7P0Z4C8|A0A7P0Z4C8_HUMAN,tr|A0A7P0Z4A4|A0A7P0Z4A4_HUMAN,tr|A0A7P0Z445|A0A7P0Z445_HUMAN,tr|A0A7P0TAA6|A0A7P0TAA6_HUMAN,tr|A0A7P0T832|A0A7P0T832_HUMAN,tr|A0A7P0T9B1|A0A7P0T9B1_HUMAN,tr|A0A7P0T9E5|A0A7P0T9E5_HUMAN,tr|A0A7P0TBB8|A0A7P0TBB8_HUMAN,tr|A0A7P0Z462|A0A7P0Z462_HUMAN,tr|A0A7P0TBE4|A0A7P0TBE4_HUMAN,tr|A0A7P0TB08|A0A7P0TB08_HUMAN,tr|A0A7P0TA65|A0A7P0TA65_HUMAN,tr|A0A7P0T824|A0A7P0T824_HUMAN,tr|A0A7P0T9I1|A0A7P0T9I1_HUMAN,tr|A0A7P0T977|A0A7P0T977_HUMAN,tr|A0A7P0Z3Z7|A0A7P0Z3Z7_HUMAN,tr|A0A7P0TAS8|A0A7P0TAS8_HUMAN,tr|A0A7P0T9C6|A0A7P0T9C6_HUMAN,tr|A0A7P0TBI6|A0A7P0TBI6_HUMAN,tr|A0A7P0TB15|A0A7P0TB15_HUMAN,tr|A0A7P0T952|A0A7P0T952_HUMAN" 29 1011.5713 0.59 109756 3251 2 1011.569528 506.7929 Serine\threonine-protein kinase VRK1 OS=Homo sapiens OX=9606 GN=VRK1 PE=1 SV=1 8.64 1275.4 - 700789 - - - -1.7468 - 1.338 0.205 - 145 1 2 0 -0.0018 9 0 0 0 1.02E+07 1.75E+07 - - - 1.397 0.9957 221125_WJC_METTL3_EV_vs_WT_F08.03252.03252.2 0.00441 18-Sep R.IQESC[160.03]QSGTK[136.11].W "sp|Q9BSJ6|PIMRE_HUMAN,tr|I3L156|I3L156_HUMAN,tr|I3L419|I3L419_HUMAN" 3 1144.5274 0.81 109757 3252 2 1144.522783 573.271 Protein PIMREG OS=Homo sapiens OX=9606 GN=PIMREG PE=1 SV=1 5.99 1275.5 - 359577 - - - -4.0235 - 1.902 0.31 - 198.2 1 2 0 -0.0046 10 0 0 0 2.45E+07 3.02E+07 - - - 3.1238 0.9993 221125_WJC_METTL3_EV_vs_WT_F08.03255.03255.2 0.214 12-Aug K.KAEYEER.A "sp|Q86U86|PB1_HUMAN,sp|Q13018|PLA2R_HUMAN" 2 923.4349 1.02 109758 3255 2 923.433472 462.7247 Protein polybromo-1 OS=Homo sapiens OX=9606 GN=PBRM1 PE=1 SV=1 4.79 1275.9 - 1.59E+06 - - - -1.5042 - 1.668 0.326 - 282.9 1 2 0 -0.0014 7 0 0 0 2.46E+07 2.40E+07 - - - 3.0695 0.9998 221125_WJC_METTL3_EV_vs_WT_F08.03258.03258.2 0.000602 18-Oct R.IQESC[160.03]QSGTK.W "sp|Q9BSJ6|PIMRE_HUMAN,tr|I3L156|I3L156_HUMAN,tr|I3L419|I3L419_HUMAN" 3 1136.5132 0.85 109761 3258 2 1136.511345 569.2639 Protein PIMREG OS=Homo sapiens OX=9606 GN=PIMREG PE=1 SV=1 5.99 1276.2 - 612206 - - - -1.6216 - 1.98 0.497 - 269.9 1 2 0 -0.0018 10 0 0 0 2.45E+07 2.87E+07 - - - 4.618 0.9776 221125_WJC_METTL3_EV_vs_WT_F08.03264.03264.3 0.27 Oct-36 K.APQHAQQSIR[166.11].E sp|P20248|CCNA2_HUMAN 1 1144.5977 0.45 109764 3264 3 1144.59478 382.5398 Cyclin-A2 OS=Homo sapiens OX=9606 GN=CCNA2 PE=1 SV=2 9.8 1277 - 413645 - - - -2.5284 - 1.996 0.133 - 121.6 2 2 0 -0.0029 10 0 0 0 3.38E+06 7.58E+06 - - - 1.9011 0.999 221125_WJC_METTL3_EV_vs_WT_F08.03276.03276.2 0.0164 14-Jun R.YQDTHPER[166.11].L "sp|Q96IJ6|GMPPA_HUMAN,tr|A0A804HIS0|A0A804HIS0_HUMAN,tr|F8WD54|F8WD54_HUMAN,tr|C9JAH0|C9JAH0_HUMAN,tr|A0A087WUI8|A0A087WUI8_HUMAN" 5 1054.4707 1.59 109772 3276 2 1054.468795 528.2426 Mannose-1-phosphate guanyltransferase alpha OS=Homo sapiens OX=9606 GN=GMPPA PE=1 SV=1 5.32 1278.5 - 420092 - - - -1.8464 - 1.279 0.43 - 135.8 1 2 0 -0.0019 8 0 0 0 9.24E+06 5.81E+06 - - - 2.9585 0.9962 221125_WJC_METTL3_EV_vs_WT_F08.03292.03292.2 0.000245 18-Aug R.GGDQQSGYGK.V tr|H0YA96|H0YA96_HUMAN 1 995.4308 0.57 109780 3292 2 995.426135 498.7227 Heterogeneous nuclear ribonucleoprotein D0 (Fragment) OS=Homo sapiens OX=9606 GN=HNRNPD PE=1 SV=1 5.83 1280.4 - 988392 - - - -4.7246 - 1.675 0.455 - 292.8 1 2 0 -0.0047 10 0 0 0 9.40E+06 1.66E+07 - - - 3.8399 0.9952 221125_WJC_METTL3_EV_vs_WT_F08.03299.03299.2 0.00411 14-Jul K.QQQDQVDR[166.11].N "sp|Q15233|NONO_HUMAN,tr|A0A7I2V535|A0A7I2V535_HUMAN,tr|A0A7I2V4N2|A0A7I2V4N2_HUMAN,tr|A0A7I2V4K9|A0A7I2V4K9_HUMAN,tr|A0A7I2V464|A0A7I2V464_HUMAN,tr|A0A7P0MRW0|A0A7P0MRW0_HUMAN,tr|H7C367|H7C367_HUMAN,tr|A0A7I2V4J2|A0A7I2V4J2_HUMAN,tr|A0A7I2V5Y7|A0A7I2V5Y7_HUMAN,tr|C9JYS8|C9JYS8_HUMAN" 10 1025.4766 0.77 109785 3299 2 1025.474569 513.7456 Non-POU domain-containing octamer-binding protein OS=Homo sapiens OX=9606 GN=NONO PE=1 SV=4 4.21 1281.3 - 3.65E+06 - - - -1.9376 - 1.661 0.149 - 300.5 1 2 0 -0.002 8 0 0 0 5.51E+08 7.11E+08 - - - 1.6712 0.9958 221125_WJC_METTL3_EV_vs_WT_F08.03301.03301.2 0.00392 16-Aug R.C[160.03]GESGHLAR.E sp|P62633|CNBP_HUMAN 1 985.44 1.55 109787 3301 2 985.442674 493.7273 CCHC-type zinc finger nucleic acid binding protein OS=Homo sapiens OX=9606 GN=CNBP PE=1 SV=1 6.74 1281.4 - 1.42E+06 - - - 2.7511 - 1.695 0.253 - 217.8 2 2 0 0.0027 9 0 0 0 9.58E+07 6.17E+07 - - - 2.301 0.8865 221125_WJC_METTL3_EV_vs_WT_F08.03302.03302.2 2.82 14-Jul K.LQEEER[166.11]ER[166.11].R "sp|P08708|RS17_HUMAN,tr|H3BNC9|H3BNC9_HUMAN,tr|H0YN88|H0YN88_HUMAN,tr|A0A075B716|A0A075B716_HUMAN" 4 1107.5423 1.35 109788 3302 2 1107.540344 554.7784 40S ribosomal protein S17 OS=Homo sapiens OX=9606 GN=RPS17 PE=1 SV=2 4.49 1281.5 - 1.31E+06 - - - -1.8031 - 1.406 0.122 - 89.2 1 2 1 -0.002 8 0 0 0 4.13E+08 3.06E+08 - - - 0.9691 0.9997 221125_WJC_METTL3_EV_vs_WT_F08.03303.03303.2 0.000393 14-Oct R.HDSPEDVK.R "sp|P31948|STIP1_HUMAN,tr|H0YGI8|H0YGI8_HUMAN" 2 925.4141 1.33 109789 3303 2 925.41317 463.7143 Stress-induced-phosphoprotein 1 OS=Homo sapiens OX=9606 GN=STIP1 PE=1 SV=1 4.54 1281.6 - 1.28E+06 - - - -1.032 - 1.749 0.393 - 381.1 1 2 0 -0.001 8 0 0 0 1.46E+08 1.10E+08 - - - 3.6294 0.9986 221125_WJC_METTL3_EV_vs_WT_F08.03304.03304.2 0.0895 18-Oct K.R[166.11]ATVVESSEK[136.11].A sp|P61981|1433G_HUMAN 1 1122.6 1.14 109790 3304 2 1122.59793 562.3073 14-3-3 protein gamma OS=Homo sapiens OX=9606 GN=YWHAG PE=1 SV=2 6.14 1281.7 - 583327 - - - -1.819 - 2.051 0.214 - 222.6 1 2 0 -0.002 10 0 0 0 1.69E+07 1.49E+07 - - - 2.626 0.8705 221125_WJC_METTL3_EV_vs_WT_F08.03305.03305.2 0.0232 14-Jul C.GESGHLAR[166.11].E sp|P62633|CNBP_HUMAN 1 835.4176 2.09 109791 3305 2 835.415693 418.7161 CCHC-type zinc finger nucleic acid binding protein OS=Homo sapiens OX=9606 GN=CNBP PE=1 SV=1 6.75 1281.8 - 487604 - - - -2.2635 - 1.524 0.285 - 296.5 1 1 0 -0.0019 8 0 0 0 2.35E+07 1.13E+07 - - - 2.4162 0.9927 221125_WJC_METTL3_EV_vs_WT_F08.03308.03308.2 0.0368 18-Jul K.QAPGSDSQPR.C "sp|Q9NXE4|NSMA3_HUMAN,tr|H7C0W5|H7C0W5_HUMAN,tr|H7C2E2|H7C2E2_HUMAN,tr|H7C2J2|H7C2J2_HUMAN,tr|H7C1Q6|H7C1Q6_HUMAN,tr|A0A7P0TB44|A0A7P0TB44_HUMAN,tr|A0A7P0T9J6|A0A7P0T9J6_HUMAN,tr|A0A7P0TB24|A0A7P0TB24_HUMAN" 8 1041.4839 3.08 109794 3308 2 1041.486754 521.7492 Sphingomyelin phosphodiesterase 4 OS=Homo sapiens OX=9606 GN=SMPD4 PE=1 SV=3 5.84 1282.2 - 115422 - - - 2.7058 - 1.181 0.312 - 97.1 1 2 0 0.0028 10 0 0 0 1.68E+07 5.46E+06 - - - 1.8089 0.9184 221125_WJC_METTL3_EV_vs_WT_F08.03311.03311.2 4.43 18-Jul R.SAVPPGADKK.A "sp|P46783|RS10_HUMAN,tr|F6U211|F6U211_HUMAN,tr|A0A1W2PQS6|A0A1W2PQS6_HUMAN,tr|A0A2R8YFH6|A0A2R8YFH6_HUMAN,tr|A0A2R8Y7H1|A0A2R8Y7H1_HUMAN,tr|S4R435|S4R435_HUMAN" 6 968.5291 1.32 109796 3311 2 968.5273 485.2718 40S ribosomal protein S10 OS=Homo sapiens OX=9606 GN=RPS10 PE=1 SV=1 8.31 1282.6 - 1.96E+06 - - - -1.8533 - 1.197 0.015 - 169.1 1 2 0 -0.0018 10 0 0 0 4.67E+07 3.53E+07 - - - -0.3468 0.9986 221125_WJC_METTL3_EV_vs_WT_F08.03314.03314.2 0.0114 14-Aug R.TSGSGFHR[166.11].E sp|Q15007|FL2D_HUMAN 1 857.4019 0.99 109798 3314 2 857.400053 429.7082 Pre-mRNA-splicing regulator WTAP OS=Homo sapiens OX=9606 GN=WTAP PE=1 SV=2 9.44 1282.8 - 3.83E+06 - - - -2.1938 - 1.533 0.35 - 328.1 1 2 0 -0.0019 8 0 0 0 6.13E+07 6.19E+07 - - - 2.914 0.9986 221125_WJC_METTL3_EV_vs_WT_F08.03318.03318.2 0.0139 14-Aug K.ETLEQQK[136.11]R[166.11].L "sp|P53621|COPA_HUMAN,tr|A0A3B3ISC6|A0A3B3ISC6_HUMAN,tr|A0A3B3IS84|A0A3B3IS84_HUMAN,tr|A0A3B3ITI7|A0A3B3ITI7_HUMAN,tr|A0A3B3IT15|A0A3B3IT15_HUMAN" 5 1048.5632 1.11 109802 3318 2 1048.56096 525.2889 Coatomer subunit alpha OS=Homo sapiens OX=9606 GN=COPA PE=1 SV=2 6.24 1283.2 - 619377 - - - -2.1296 - 1.592 0.33 - 333.8 1 2 0 -0.0022 8 0 0 0 9.94E+06 8.93E+06 - - - 2.8801 0.9899 221125_WJC_METTL3_EV_vs_WT_F08.03325.03325.2 0.0721 14-Aug K.QQQDQVDR.N "sp|Q15233|NONO_HUMAN,tr|A0A7I2V535|A0A7I2V535_HUMAN,tr|A0A7I2V4N2|A0A7I2V4N2_HUMAN,tr|A0A7I2V4K9|A0A7I2V4K9_HUMAN,tr|A0A7I2V464|A0A7I2V464_HUMAN,tr|A0A7P0MRW0|A0A7P0MRW0_HUMAN,tr|H7C367|H7C367_HUMAN,tr|A0A7I2V4J2|A0A7I2V4J2_HUMAN,tr|A0A7I2V5Y7|A0A7I2V5Y7_HUMAN,tr|C9JYS8|C9JYS8_HUMAN" 10 1015.4683 0.77 109807 3325 2 1015.465779 508.7414 Non-POU domain-containing octamer-binding protein OS=Homo sapiens OX=9606 GN=NONO PE=1 SV=4 4.21 1284.1 - 3.19E+07 - - - -2.4688 - 1.853 0.067 - 412.5 1 2 0 -0.0025 8 0 0 0 5.51E+08 7.11E+08 - - - 1.3953 0.9996 221125_WJC_METTL3_EV_vs_WT_F08.03329.03329.2 0.000295 14-Aug R.GDDETLHK.N sp|P35580|MYH10_HUMAN 1 913.4141 6.59 109811 3329 2 913.41195 457.7143 Myosin-10 OS=Homo sapiens OX=9606 GN=MYH10 PE=1 SV=3 4.54 1284.3 - 1.90E+06 - - - -2.3812 - 1.7 0.515 - 326.5 1 2 0 -0.0022 8 0 0 0 5.95E+07 9.03E+06 - - - 4.4445 0.9952 221125_WJC_METTL3_EV_vs_WT_F08.03339.03339.2 0.0229 16-Aug K.LQQEEVQKK.N sp|Q86UP2|KTN1_HUMAN 1 1128.6139 1.99 109817 3339 2 1128.611537 565.3142 Kinectin OS=Homo sapiens OX=9606 GN=KTN1 PE=1 SV=1 6.14 1285.4 - 1.08E+06 - - - -2.0831 - 1.57 0.19 - 205.8 1 2 0 -0.0024 9 0 0 0 1.15E+07 5.79E+06 - - - 1.7486 0.9997 221125_WJC_METTL3_EV_vs_WT_F08.03345.03345.2 0.0598 13/14 K.K[136.11]GQEVC[160.03]VK[136.11].L "sp|O60841|IF2P_HUMAN,tr|A0A087WUT6|A0A087WUT6_HUMAN" 2 962.519 0.44 109821 3345 2 962.517072 482.2668 Eukaryotic translation initiation factor 5B OS=Homo sapiens OX=9606 GN=EIF5B PE=1 SV=4 8.2 1286.1 - 1.13E+06 - - - -2.0052 - 2.418 0.408 - 585.8 1 2 0 -0.0019 8 0 0 0 9.06E+06 2.08E+07 - - - 4.7168 0.9978 221125_WJC_METTL3_EV_vs_WT_F08.03346.03346.2 0.0447 14-Aug R.YHQIGSGK[136.11].C "sp|O14979|HNRDL_HUMAN,tr|A0A087WUK2|A0A087WUK2_HUMAN" 2 896.4596 1.36 109822 3346 2 896.457081 449.2371 Heterogeneous nuclear ribonucleoprotein D-like OS=Homo sapiens OX=9606 GN=HNRNPDL PE=1 SV=3 8.6 1286.3 - 754216 - - - -2.772 - 1.654 0.314 - 301.1 1 2 0 -0.0025 8 0 0 0 8.92E+07 6.56E+07 - - - 2.877 0.9983 221125_WJC_METTL3_EV_vs_WT_F08.03352.03352.2 7.02E-05 14-Sep R.YHQIGSGK.C "sp|O14979|HNRDL_HUMAN,tr|A0A087WUK2|A0A087WUK2_HUMAN" 2 888.4454 1.36 109826 3352 2 888.441919 445.23 Heterogeneous nuclear ribonucleoprotein D-like OS=Homo sapiens OX=9606 GN=HNRNPDL PE=1 SV=3 8.6 1287 - 3.00E+06 - - - -3.8798 - 1.703 0.467 - 383.7 1 2 0 -0.0034 8 0 0 0 8.93E+07 6.55E+07 - - - 4.0948 0.9997 221125_WJC_METTL3_EV_vs_WT_F08.03355.03355.2 0.00094 20-Oct R.AVETTAQSDNK[136.11].L sp|P38606|VATA_HUMAN 1 1170.5608 1.08 109829 3355 2 1170.558259 586.2877 V-type proton ATPase catalytic subunit A OS=Homo sapiens OX=9606 GN=ATP6V1A PE=1 SV=2 4.37 1287.4 - 485800 - - - -2.1673 - 2.061 0.489 - 273.1 1 2 0 -0.0025 11 0 0 0 2.01E+07 1.86E+07 - - - 4.6084 0.7623 221125_WJC_METTL3_EV_vs_WT_F08.03358.03358.2 0.0164 12-Jun G.DDETLHK[136.11].N sp|P35580|MYH10_HUMAN 1 864.4069 1.33 109830 3358 2 864.40471 433.2107 Myosin-10 OS=Homo sapiens OX=9606 GN=MYH10 PE=1 SV=3 4.54 1287.7 - 1.23E+06 - - - -2.4884 - 1.242 0.298 - 109.1 1 1 0 -0.0022 7 0 0 0 2.92E+07 2.20E+07 - - - 1.9281 0.9996 221125_WJC_METTL3_EV_vs_WT_F08.03359.03359.2 0.000835 20-Nov R.AVETTAQSDNK.L sp|P38606|VATA_HUMAN 1 1162.5466 1.08 109831 3359 2 1162.543017 582.2806 V-type proton ATPase catalytic subunit A OS=Homo sapiens OX=9606 GN=ATP6V1A PE=1 SV=2 4.37 1287.9 - 973824 - - - -3.0786 - 2.403 0.537 - 357.8 1 2 0 -0.0036 11 0 0 0 2.01E+07 1.86E+07 - - - 5.3779 0.9971 221125_WJC_METTL3_EV_vs_WT_F08.03361.03361.2 0.0192 22-Jun K.EGNNPAENGDAK.T sp|P05204|HMGN2_HUMAN 1 1214.5164 0.84 109833 3361 2 1214.513117 608.2655 Non-histone chromosomal protein HMG-17 OS=Homo sapiens OX=9606 GN=HMGN2 PE=1 SV=3 4.14 1288.1 - 306397 - - - -2.6686 - 1.213 0.405 - 73 1 2 0 -0.0032 12 0 0 0 3.04E+08 3.63E+08 - - - 2.5394 0.9992 221125_WJC_METTL3_EV_vs_WT_F08.03364.03364.2 0.0102 18-Nov R.RSAVPPGADK.K "sp|P46783|RS10_HUMAN,tr|F6U211|F6U211_HUMAN,tr|A0A1W2PQS6|A0A1W2PQS6_HUMAN,tr|A0A2R8YFH6|A0A2R8YFH6_HUMAN,tr|A0A2R8Y7H1|A0A2R8Y7H1_HUMAN,tr|S4R435|S4R435_HUMAN" 6 996.5352 1 109834 3364 2 996.532516 499.2749 40S ribosomal protein S10 OS=Homo sapiens OX=9606 GN=RPS10 PE=1 SV=1 8.75 1288.5 - 3.25E+06 - - - -2.7365 - 2.187 0.37 - 385.5 1 2 0 -0.0027 10 0 0 0 6.62E+07 6.59E+07 - - - 3.9572 0.8963 221125_WJC_METTL3_EV_vs_WT_F08.03368.03368.2 0.0356 12-Sep R.QREEYER.A sp|P12270|TPR_HUMAN 1 1008.4625 0.45 109838 3368 2 1008.458616 505.2385 Nucleoprotein TPR OS=Homo sapiens OX=9606 GN=TPR PE=1 SV=3 4.79 1288.8 - 1.37E+06 - - - -3.8236 - 1.643 0.211 - 281.3 1 2 1 -0.0039 7 0 0 0 1.90E+07 4.18E+07 - - - 2.1715 0.9999 221125_WJC_METTL3_EV_vs_WT_F08.03371.03371.2 1.69E-05 18-Nov R.C[160.03]ETC[160.03]GTEEAK.Y sp|Q9NWK9|BCD1_HUMAN 1 1183.4485 1.19 109841 3371 2 1183.446902 592.7315 Box C\D snoRNA protein 1 OS=Homo sapiens OX=9606 GN=ZNHIT6 PE=1 SV=1 4.25 1289.2 - 806614 - - - -1.3832 - 2.17 0.605 - 326.9 1 2 0 -0.0016 10 0 0 0 7.57E+06 6.38E+06 - - - 5.6715 0.9792 221125_WJC_METTL3_EV_vs_WT_F08.03372.03372.2 0.000837 18-Aug K.SEEESAETTK[136.11].E sp|Q9NVP1|DDX18_HUMAN 1 1117.4866 1.41 109842 3372 2 1117.479817 559.7506 ATP-dependent RNA helicase DDX18 OS=Homo sapiens OX=9606 GN=DDX18 PE=1 SV=2 4.09 1289.3 - 537100 - - - -6.0949 - 1.805 0.313 - 221.2 1 2 0 -0.0068 10 0 0 0 6.48E+06 4.59E+06 - - - 2.9991 0.9998 221125_WJC_METTL3_EV_vs_WT_F08.03373.03373.2 8.39E-07 18-Dec R.C[160.03]ETC[160.03]GTEEAK[136.11].Y sp|Q9NWK9|BCD1_HUMAN 1 1191.4627 1.19 109843 3373 2 1191.460937 596.7386 Box C\D snoRNA protein 1 OS=Homo sapiens OX=9606 GN=ZNHIT6 PE=1 SV=1 4.25 1289.5 - 532999 - - - -1.5124 - 2.385 0.449 - 695.4 1 2 0 -0.0018 10 0 0 0 7.57E+06 6.38E+06 - - - 4.7829 0.999 221125_WJC_METTL3_EV_vs_WT_F08.03378.03378.2 0.000187 14-Aug K.TGNAWHSK[136.11].N "sp|P09874|PARP1_HUMAN,tr|A0A7I2V3E1|A0A7I2V3E1_HUMAN" 2 907.4392 0.89 109846 3378 2 907.43568 454.7269 Poly [ADP-ribose] polymerase 1 OS=Homo sapiens OX=9606 GN=PARP1 PE=1 SV=4 8.44 1290.1 - 4.66E+06 - - - -3.8405 - 1.943 0.529 - 257.9 1 2 0 -0.0035 8 0 0 0 7.34E+07 8.24E+07 - - - 4.9504 0.9966 221125_WJC_METTL3_EV_vs_WT_F08.03379.03379.2 0.00259 18-Nov R.R[166.11]SAVPPGADK[136.11].K "sp|P46783|RS10_HUMAN,tr|F6U211|F6U211_HUMAN,tr|A0A1W2PQS6|A0A1W2PQS6_HUMAN,tr|A0A2R8YFH6|A0A2R8YFH6_HUMAN,tr|A0A2R8Y7H1|A0A2R8Y7H1_HUMAN,tr|S4R435|S4R435_HUMAN" 6 1014.5577 1.06 109847 3379 2 1014.553312 508.2861 40S ribosomal protein S10 OS=Homo sapiens OX=9606 GN=RPS10 PE=1 SV=1 8.75 1290.1 - 3.93E+06 - - - -4.3379 - 2.006 0.36 - 437.7 1 2 0 -0.0044 10 0 0 0 6.40E+07 6.07E+07 - - - 3.6417 0.9978 221125_WJC_METTL3_EV_vs_WT_F08.03382.03382.2 0.000321 16-Sep K.AEGNDHIER[166.11].A "sp|Q15155|NOMO1_HUMAN,sp|Q5JPE7|NOMO2_HUMAN,sp|P69849|NOMO3_HUMAN,tr|A0A7I2V3P4|A0A7I2V3P4_HUMAN,tr|A0A7I2V6B0|A0A7I2V6B0_HUMAN,tr|A0A7I2V4T6|A0A7I2V4T6_HUMAN,tr|A0A0G2JP90|A0A0G2JP90_HUMAN,tr|A0A087WTD5|A0A087WTD5_HUMAN,tr|A0A087X117|A0A087X117_HUMAN,tr|A0A0G2JN29|A0A0G2JN29_HUMAN,tr|A0A7I2V2Z5|A0A7I2V2Z5_HUMAN,tr|A0A087WW46|A0A087WW46_HUMAN,tr|J3KN36|J3KN36_HUMAN" 13 1049.4766 1.91 109850 3382 2 1049.471498 525.7456 Nodal modulator 1 OS=Homo sapiens OX=9606 GN=NOMO1 PE=1 SV=5 4.65 1290.5 - 1.19E+06 - - - -4.8195 - 1.941 0.514 - 434 1 2 0 -0.0051 9 0 0 0 2.71E+07 1.42E+07 - - - 4.7545 0.9999 221125_WJC_METTL3_EV_vs_WT_F08.03390.03390.3 2.69E-07 14/48 K.KPAAAAAPGTAEK.L "sp|P50454|SERPH_HUMAN,tr|E9PNX1|E9PNX1_HUMAN,tr|E9PIG2|E9PIG2_HUMAN,tr|E9PPV6|E9PPV6_HUMAN,tr|E9PR70|E9PR70_HUMAN,tr|E9PMI5|E9PMI5_HUMAN,tr|E9PRS3|E9PRS3_HUMAN,tr|E9PJH8|E9PJH8_HUMAN,tr|E9PK86|E9PK86_HUMAN,tr|E9PQ34|E9PQ34_HUMAN" 10 1181.6404 2.39 109854 3390 3 1181.635923 394.8874 Serpin H1 OS=Homo sapiens OX=9606 GN=SERPINH1 PE=1 SV=2 8.59 1291.3 - 1.78E+06 - - - -3.8201 - 2.527 0.534 - 443.3 1 2 0 -0.0045 13 0 0 0 3.47E+07 1.45E+07 - - - 7.0058 0.9998 221125_WJC_METTL3_EV_vs_WT_F08.03392.03392.2 2.82E-05 18-Sep R.AQSELAAHQK[136.11].K "sp|P25786|PSA1_HUMAN,tr|F5GX11|F5GX11_HUMAN,tr|B4DEV8|B4DEV8_HUMAN" 3 1089.5658 0.86 109856 3392 2 1089.565058 545.7902 Proteasome subunit alpha type-1 OS=Homo sapiens OX=9606 GN=PSMA1 PE=1 SV=1 6.79 1291.5 - 1.44E+06 - - - -0.7012 - 2.054 0.451 - 362.5 1 2 0 -0.0008 10 0 0 0 1.94E+07 2.25E+07 - - - 4.381 0.9993 221125_WJC_METTL3_EV_vs_WT_F08.03393.03393.2 0.000168 14/16 K.R[166.11]IVENGQER[166.11].V "sp|Q8NHS0|DNJB8_HUMAN,sp|O75190|DNJB6_HUMAN,tr|A0A0J9YX62|A0A0J9YX62_HUMAN,tr|C9J2C4|C9J2C4_HUMAN" 4 1119.59 1.37 109857 3393 2 1119.585652 560.8023 DnaJ homolog subfamily B member 8 OS=Homo sapiens OX=9606 GN=DNAJB8 PE=1 SV=1 6.14 1291.7 - 1.07E+06 - - - -3.8478 - 2.608 0.505 - 338.6 1 2 0 -0.0043 9 0 0 0 3.19E+07 2.33E+07 - - - 5.5428 0.9994 221125_WJC_METTL3_EV_vs_WT_F08.03397.03397.2 5.03E-05 14/16 K.RIVENGQER.V "sp|Q8NHS0|DNJB8_HUMAN,sp|O75190|DNJB6_HUMAN,tr|A0A0J9YX62|A0A0J9YX62_HUMAN,tr|C9J2C4|C9J2C4_HUMAN" 4 1099.5734 1.37 109858 3397 2 1099.569671 550.794 DnaJ homolog subfamily B member 8 OS=Homo sapiens OX=9606 GN=DNAJB8 PE=1 SV=1 6.14 1292.2 - 2.19E+06 - - - -3.4095 - 2.483 0.479 - 350.7 1 2 0 -0.0037 9 0 0 0 3.19E+07 2.33E+07 - - - 5.2089 0.9994 221125_WJC_METTL3_EV_vs_WT_F08.03398.03398.2 0.055 14-Aug K.HIAEEADR.K "sp|P67936|TPM4_HUMAN,sp|P06753|TPM3_HUMAN,tr|A0A2R8Y5V9|A0A2R8Y5V9_HUMAN,tr|A0A5F9UN72|A0A5F9UN72_HUMAN,tr|A0A2R8YEU4|A0A2R8YEU4_HUMAN,tr|A0A2R8YGX3|A0A2R8YGX3_HUMAN,tr|A0A2R2Y2Q3|A0A2R2Y2Q3_HUMAN,tr|A0A087WWU8|A0A087WWU8_HUMAN,tr|K7ENT6|K7ENT6_HUMAN,tr|J3KN67|J3KN67_HUMAN,tr|A0A494C0P6|A0A494C0P6_HUMAN,tr|A0A2R8YH90|A0A2R8YH90_HUMAN,tr|A0A2R8YE05|A0A2R8YE05_HUMAN,tr|A0A2R8YHD2|A0A2R8YHD2_HUMAN" 14 939.441 1.73 109859 3398 2 939.439753 470.7278 Tropomyosin alpha-4 chain OS=Homo sapiens OX=9606 GN=TPM4 PE=1 SV=3 4.65 1292.3 - 1.34E+06 - - - -1.337 - 1.613 0.36 - 232 1 2 0 -0.0013 8 0 0 0 1.77E+07 1.02E+07 - - - 3.1415 0.9996 221125_WJC_METTL3_EV_vs_WT_F08.03399.03399.2 8.21E-05 13/16 K.K[136.11]VDQPPEAK[136.11].K "sp|Q92598|HS105_HUMAN,tr|A0A0A0MSM0|A0A0A0MSM0_HUMAN" 2 1026.5681 0.03 109860 3399 2 1026.565324 514.2913 Heat shock protein 105 kDa OS=Homo sapiens OX=9606 GN=HSPH1 PE=1 SV=1 6.07 1292.4 - 1.94E+06 - - - -2.6652 - 2.389 0.478 - 596.4 1 2 0 -0.0027 9 0 0 0 6.26E+05 2.26E+07 - - - 5.0901 0.9954 221125_WJC_METTL3_EV_vs_WT_F08.03400.03400.2 0.0196 14-Jul K.HIAEEADR[166.11].K "sp|P67936|TPM4_HUMAN,sp|P06753|TPM3_HUMAN,tr|A0A2R8Y5V9|A0A2R8Y5V9_HUMAN,tr|A0A5F9UN72|A0A5F9UN72_HUMAN,tr|A0A2R8YEU4|A0A2R8YEU4_HUMAN,tr|A0A2R8YGX3|A0A2R8YGX3_HUMAN,tr|A0A2R2Y2Q3|A0A2R2Y2Q3_HUMAN,tr|A0A087WWU8|A0A087WWU8_HUMAN,tr|K7ENT6|K7ENT6_HUMAN,tr|J3KN67|J3KN67_HUMAN,tr|A0A494C0P6|A0A494C0P6_HUMAN,tr|A0A2R8YH90|A0A2R8YH90_HUMAN,tr|A0A2R8YE05|A0A2R8YE05_HUMAN,tr|A0A2R8YHD2|A0A2R8YHD2_HUMAN" 14 949.4493 2.82 109861 3400 2 949.445636 475.7319 Tropomyosin alpha-4 chain OS=Homo sapiens OX=9606 GN=TPM4 PE=1 SV=3 4.65 1292.5 - 1.49E+06 - - - -3.837 - 1.52 0.354 - 178.2 1 2 0 -0.0036 8 0 0 0 3.01E+07 1.07E+07 - - - 2.9173 1 221125_WJC_METTL3_EV_vs_WT_F08.03403.03403.2 0.000223 15/24 K.K[136.11]PAAAAAPGTAEK[136.11].L "sp|P50454|SERPH_HUMAN,tr|E9PNX1|E9PNX1_HUMAN,tr|E9PIG2|E9PIG2_HUMAN,tr|E9PPV6|E9PPV6_HUMAN,tr|E9PR70|E9PR70_HUMAN,tr|E9PMI5|E9PMI5_HUMAN,tr|E9PRS3|E9PRS3_HUMAN,tr|E9PJH8|E9PJH8_HUMAN,tr|E9PK86|E9PK86_HUMAN,tr|E9PQ34|E9PQ34_HUMAN" 10 1197.6688 1.82 109863 3403 2 1197.663293 599.8417 Serpin H1 OS=Homo sapiens OX=9606 GN=SERPINH1 PE=1 SV=2 8.59 1292.9 - 492298 - - - -4.629 - 3.275 0.528 - 656.5 1 2 0 -0.0055 13 0 0 0 1.08E+07 5.97E+06 - - - 5.9838 0.999 221125_WJC_METTL3_EV_vs_WT_F08.03406.03406.2 0.0026 18-Sep R.SSSVSSSPAR.T sp|Q9UI36|DACH1_HUMAN 1 963.4621 1.9 109864 3406 2 963.46002 482.7383 Dachshund homolog 1 OS=Homo sapiens OX=9606 GN=DACH1 PE=1 SV=4 9.47 1293.3 - 3.95E+06 - - - -2.1983 - 1.929 0.324 - 304.2 1 2 0 -0.0021 10 0 0 0 7.76E+07 4.09E+07 - - - 3.2673 0.9991 221125_WJC_METTL3_EV_vs_WT_F08.03408.03408.2 0.00164 18-Aug R.AQQEAEAAQR[166.11].L "sp|Q99426|TBCB_HUMAN,tr|A0A494C0X0|A0A494C0X0_HUMAN,tr|K7EP07|K7EP07_HUMAN,tr|K7EK42|K7EK42_HUMAN" 4 1110.5293 0.8 109866 3408 2 1110.526777 556.2719 Tubulin-folding cofactor B OS=Homo sapiens OX=9606 GN=TBCB PE=1 SV=2 4.53 1293.5 - 1.52E+06 - - - -2.2899 - 1.924 0.35 - 282.1 1 2 0 -0.0025 10 0 0 0 8.52E+06 1.06E+07 - - - 3.4519 0.9985 221125_WJC_METTL3_EV_vs_WT_F08.03409.03409.2 3.92E-05 18-Sep K.QPTEEEASSK.E "sp|Q15459|SF3A1_HUMAN,tr|F8WB66|F8WB66_HUMAN" 2 1104.4935 0.83 109867 3409 2 1104.488887 553.254 Splicing factor 3A subunit 1 OS=Homo sapiens OX=9606 GN=SF3A1 PE=1 SV=1 4.25 1293.7 - 1.18E+06 - - - -4.1748 - 1.936 0.503 - 373.5 1 2 0 -0.0046 10 0 0 0 1.94E+07 2.33E+07 - - - 4.5987 0.9996 221125_WJC_METTL3_EV_vs_WT_F08.03410.03410.2 0.0178 13/16 R.KGAAPAPPR.K "sp|Q13428|TCOF_HUMAN,tr|E7ETY2|E7ETY2_HUMAN,tr|H0Y8Y7|H0Y8Y7_HUMAN,tr|A0A3B3IS06|A0A3B3IS06_HUMAN,tr|A0A6I8PRA0|A0A6I8PRA0_HUMAN" 5 863.4977 1.27 109868 3410 2 863.496044 432.7561 Treacle protein OS=Homo sapiens OX=9606 GN=TCOF1 PE=1 SV=3 11 1293.8 - 1.14E+06 - - - -1.9595 - 2.404 0.337 - 596.9 1 2 0 -0.0017 9 0 0 0 2.23E+07 1.75E+07 - - - 4.0671 1 221125_WJC_METTL3_EV_vs_WT_F08.03412.03412.2 1.83E-05 16/24 K.KPAAAAAPGTAEK.L "sp|P50454|SERPH_HUMAN,tr|E9PNX1|E9PNX1_HUMAN,tr|E9PIG2|E9PIG2_HUMAN,tr|E9PPV6|E9PPV6_HUMAN,tr|E9PR70|E9PR70_HUMAN,tr|E9PMI5|E9PMI5_HUMAN,tr|E9PRS3|E9PRS3_HUMAN,tr|E9PJH8|E9PJH8_HUMAN,tr|E9PK86|E9PK86_HUMAN,tr|E9PQ34|E9PQ34_HUMAN" 10 1181.6404 1.82 109870 3412 2 1181.636032 591.8275 Serpin H1 OS=Homo sapiens OX=9606 GN=SERPINH1 PE=1 SV=2 8.59 1294 - 962595 - - - -3.7279 - 3.144 0.58 - 686.1 1 2 0 -0.0044 13 0 0 0 1.08E+07 5.97E+06 - - - 6.2634 0.9325 221125_WJC_METTL3_EV_vs_WT_F08.03413.03413.2 0.00493 16-Nov K.AEK[136.11]DNAEIR[166.11].V sp|Q99832|TCPH_HUMAN 1 1062.5425 0.21 109871 3413 2 1062.536285 532.2785 T-complex protein 1 subunit eta OS=Homo sapiens OX=9606 GN=CCT7 PE=1 SV=2 4.68 1294.1 - 606596 - - - -5.8087 - 2.058 0.41 - 386.3 1 2 1 -0.0062 9 0 0 0 2.26E+07 1.09E+08 - - - 4.1553 0.986 221125_WJC_METTL3_EV_vs_WT_F08.03414.03414.2 0.00129 16-Oct K.QVAQQEAQR[166.11].A "sp|Q99623|PHB2_HUMAN,tr|F5H3X6|F5H3X6_HUMAN,tr|F5GWA7|F5GWA7_HUMAN,tr|F5GY37|F5GY37_HUMAN" 4 1066.5395 1.33 109872 3414 2 1066.532634 534.277 Prohibitin-2 OS=Homo sapiens OX=9606 GN=PHB2 PE=1 SV=2 6 1294.3 - 481131 - - - -6.4292 - 2.023 0.354 - 489.2 1 2 0 -0.0069 9 0 0 0 1.95E+07 1.46E+07 - - - 3.6919 0.9989 221125_WJC_METTL3_EV_vs_WT_F08.03419.03419.2 0.00514 18-Sep R.SSSVSSSPAR[166.11].T sp|Q9UI36|DACH1_HUMAN 1 973.4704 1.9 109876 3419 2 973.467834 487.7425 Dachshund homolog 1 OS=Homo sapiens OX=9606 GN=DACH1 PE=1 SV=4 9.47 1294.7 - 3.31E+06 - - - -2.6441 - 1.917 0.364 - 311.3 1 2 0 -0.0026 10 0 0 0 7.76E+07 4.08E+07 - - - 3.5452 0.9996 221125_WJC_METTL3_EV_vs_WT_F08.03421.03421.2 1.88E-06 22-Oct K.EGNNPAENGDAK[136.11].T sp|P05204|HMGN2_HUMAN 1 1222.5306 0.84 109878 3421 2 1222.526783 612.2726 Non-histone chromosomal protein HMG-17 OS=Homo sapiens OX=9606 GN=HMGN2 PE=1 SV=3 4.14 1294.8 - 1.90E+06 - - - -3.0879 - 1.905 0.659 - 374.7 1 2 0 -0.0038 12 0 0 0 3.04E+08 3.63E+08 - - - 5.6029 0.976 221125_WJC_METTL3_EV_vs_WT_F08.03422.03422.2 0.000105 20-Nov K.PAGGPK[136.11]PPSGK[136.11].K "sp|P50990|TCPQ_HUMAN,tr|H7C2U0|H7C2U0_HUMAN" 2 1007.5735 0.41 109879 3422 2 1007.570953 504.794 T-complex protein 1 subunit theta OS=Homo sapiens OX=9606 GN=CCT8 PE=1 SV=4 10.02 1294.9 - 1.72E+06 - - - -2.508 - 2.389 0.449 - 355.8 1 1 0 -0.0025 11 0 0 0 5.74E+07 1.41E+08 - - - 4.7124 0.9302 221125_WJC_METTL3_EV_vs_WT_F08.03423.03423.2 0.269 14-Jul R.SK[136.11]EGLTER[166.11].F sp|Q15046|SYK_HUMAN 1 936.4995 0.5 109880 3423 2 936.496683 469.257 Lysine--tRNA ligase OS=Homo sapiens OX=9606 GN=KARS1 PE=1 SV=3 5.86 1294.9 - 1.46E+06 - - - -3.04 - 1.572 0.223 - 142.8 1 2 1 -0.0028 8 0 0 0 6.68E+06 1.32E+07 - - - 2.0514 0.9989 221125_WJC_METTL3_EV_vs_WT_F08.03424.03424.2 0.163 16-Oct K.QVAQQEAQR.A "sp|Q99623|PHB2_HUMAN,tr|F5H3X6|F5H3X6_HUMAN,tr|F5GWA7|F5GWA7_HUMAN,tr|F5GY37|F5GY37_HUMAN" 4 1056.5312 1.33 109881 3424 2 1056.528907 529.2729 Prohibitin-2 OS=Homo sapiens OX=9606 GN=PHB2 PE=1 SV=2 6 1295 - 1.35E+06 - - - -2.1902 - 1.934 0.299 - 490.5 1 2 0 -0.0023 9 0 0 0 1.95E+07 1.46E+07 - - - 3.1569 0.9998 221125_WJC_METTL3_EV_vs_WT_F08.03425.03425.2 2.42E-05 16-Oct R.K[136.11]GAAPAPPR[166.11].K "sp|Q13428|TCOF_HUMAN,tr|E7ETY2|E7ETY2_HUMAN,tr|H0Y8Y7|H0Y8Y7_HUMAN,tr|A0A3B3IS06|A0A3B3IS06_HUMAN,tr|A0A6I8PRA0|A0A6I8PRA0_HUMAN" 5 881.5202 1.27 109882 3425 2 881.519553 441.7674 Treacle protein OS=Homo sapiens OX=9606 GN=TCOF1 PE=1 SV=3 11 1295.1 - 1.06E+06 - - - -0.7408 - 2.073 0.471 - 310.6 1 2 0 -0.0007 9 0 0 0 2.23E+07 1.75E+07 - - - 4.6286 0.9638 221125_WJC_METTL3_EV_vs_WT_F08.03429.03429.2 0.273 14-Aug R.SKEGLTER.F sp|Q15046|SYK_HUMAN 1 918.4771 0.5 109884 3429 2 918.475803 460.2458 Lysine--tRNA ligase OS=Homo sapiens OX=9606 GN=KARS1 PE=1 SV=3 5.86 1295.6 - 982918 - - - -1.3686 - 1.353 0.233 - 180.1 1 2 1 -0.0013 8 0 0 0 6.68E+06 1.32E+07 - - - 1.6733 0.9993 221125_WJC_METTL3_EV_vs_WT_F08.03430.03430.2 0.0425 16-Aug K.ETDEVSNTK.S "sp|Q9Y520|PRC2C_HUMAN,tr|A0A0A0MS30|A0A0A0MS30_HUMAN,tr|E7EPN9|E7EPN9_HUMAN" 3 1021.4564 1.25 109885 3430 2 1021.455341 511.7355 Protein PRRC2C OS=Homo sapiens OX=9606 GN=PRRC2C PE=1 SV=4 4.14 1295.7 - 744709 - - - -1.0211 - 1.562 0.349 - 266.1 1 2 0 -0.001 9 0 0 0 2.41E+07 1.92E+07 - - - 2.9086 0.9984 221125_WJC_METTL3_EV_vs_WT_F08.03433.03433.2 0.0317 16-Sep R.HTAAQLGEK.L "sp|P55011|S12A2_HUMAN,tr|G3XAL9|G3XAL9_HUMAN" 2 953.493 0.64 109888 3433 2 953.491228 477.7538 Solute carrier family 12 member 2 OS=Homo sapiens OX=9606 GN=SLC12A2 PE=1 SV=1 6.75 1295.9 - 797038 - - - -1.9046 - 1.643 0.285 - 169.3 1 2 0 -0.0018 9 0 0 0 5.02E+06 7.80E+06 - - - 2.5819 0.9997 221125_WJC_METTL3_EV_vs_WT_F08.03434.03434.3 0.0034 15/44 K.QIGANAHGAGSR.S sp|Q8TEK3|DOT1L_HUMAN 1 1137.5639 2.49 109889 3434 3 1137.561938 380.1952 "Histone-lysine N-methyltransferase, H3 lysine-79 specific OS=Homo sapiens OX=9606 GN=DOT1L PE=1 SV=3" 9.76 1296.1 - 391399 - - - -1.7406 - 2.264 0.344 - 283.1 1 2 0 -0.002 12 0 0 0 3.92E+06 1.58E+06 - - - 4.6397 0.9611 221125_WJC_METTL3_EV_vs_WT_F08.03443.03443.2 0.28 16-Jul K.TKSDEETLK.A "sp|P35251|RFC1_HUMAN,tr|E0CX09|E0CX09_HUMAN" 2 1049.5241 0.26 109896 3443 2 1049.524395 525.7693 Replication factor C subunit 1 OS=Homo sapiens OX=9606 GN=RFC1 PE=1 SV=4 4.68 1297.2 - 288661 - - - 0.3097 - 1.25 0.228 - 122.3 1 2 1 0.0003 9 0 0 0 2.07E+06 8.08E+06 - - - 1.3705 0.9471 221125_WJC_METTL3_EV_vs_WT_F08.03444.03444.2 3 18-Mar K.NVFIWDFLEK[136.11].A "sp|Q6IQ26|DEN5A_HUMAN,sp|Q6ZUT9|DEN5B_HUMAN,tr|A0A7P0T9Z2|A0A7P0T9Z2_HUMAN,tr|G3V1S3|G3V1S3_HUMAN,tr|A0A7P0Z4N9|A0A7P0Z4N9_HUMAN,tr|H0YDS8|H0YDS8_HUMAN,tr|H0YEA8|H0YEA8_HUMAN" 7 1317.6849 0.001 109897 3444 2 1317.683811 659.8497 DENN domain-containing protein 5A OS=Homo sapiens OX=9606 GN=DENND5A PE=1 SV=2 4.37 1297.3 - 93468.1 - - - -0.8067 - 0.918 0.136 - 21.5 3 2 0 -0.0011 10 0 0 0 0.00E+00 1.40E+06 - - - -0.4068 0.9997 221125_WJC_METTL3_EV_vs_WT_F08.03447.03447.2 0.00632 16-Aug K.ETDEVSNTK[136.11].S "sp|Q9Y520|PRC2C_HUMAN,tr|A0A0A0MS30|A0A0A0MS30_HUMAN,tr|E7EPN9|E7EPN9_HUMAN" 3 1029.4706 1.25 109898 3447 2 1029.471402 515.7426 Protein PRRC2C OS=Homo sapiens OX=9606 GN=PRRC2C PE=1 SV=4 4.14 1297.8 - 2.44E+06 - - - 0.7946 - 1.744 0.442 - 277.3 1 2 0 0.0008 9 0 0 0 2.41E+07 1.92E+07 - - - 3.9144 0.9001 221125_WJC_METTL3_EV_vs_WT_F08.03448.03448.2 0.179 12-Aug E.K[136.11]DNAEIR[166.11].V sp|Q99832|TCPH_HUMAN 1 862.4628 0.4 109899 3448 2 862.461282 432.2387 T-complex protein 1 subunit eta OS=Homo sapiens OX=9606 GN=CCT7 PE=1 SV=2 6.07 1297.8 - 1.66E+06 - - - -1.7021 - 1.656 0.229 - 214.5 1 1 0 -0.0015 7 0 0 0 4.60E+06 1.15E+07 - - - 2.3302 0.97 221125_WJC_METTL3_EV_vs_WT_F08.03449.03449.2 0.272 18-Jun R.SAVPPGADK[136.11]K[136.11].A "sp|P46783|RS10_HUMAN,tr|F6U211|F6U211_HUMAN,tr|A0A1W2PQS6|A0A1W2PQS6_HUMAN,tr|A0A2R8YFH6|A0A2R8YFH6_HUMAN,tr|A0A2R8Y7H1|A0A2R8Y7H1_HUMAN,tr|S4R435|S4R435_HUMAN" 6 984.5575 1.09 109900 3449 2 984.55683 493.286 40S ribosomal protein S10 OS=Homo sapiens OX=9606 GN=RPS10 PE=1 SV=1 8.31 1297.9 - 1.59E+06 - - - -0.6754 - 1.271 0.067 - 84.4 4 2 0 -0.0007 10 0 0 0 8.55E+07 7.84E+07 - - - -0.0639 0.915 221125_WJC_METTL3_EV_vs_WT_F08.03450.03450.2 3.18 12-Jun R.DK[136.11]PAQIR[166.11].F sp|P50991|TCPD_HUMAN 1 844.4886 0.24 109901 3450 2 844.4872 423.2516 T-complex protein 1 subunit delta OS=Homo sapiens OX=9606 GN=CCT4 PE=1 SV=4 8.75 1298 - 1.50E+06 - - - -1.6235 - 1.168 0.018 - 141 2 2 0 -0.0014 7 0 0 0 1.44E+07 6.12E+07 - - - -0.4689 0.9996 221125_WJC_METTL3_EV_vs_WT_F08.03451.03451.2 0.00252 18-Sep R.GSPQQIDHAK[136.11].Q "sp|Q92945|FUBP2_HUMAN,tr|M0R3J3|M0R3J3_HUMAN,tr|M0R0C6|M0R0C6_HUMAN,tr|A0A087WTP3|A0A087WTP3_HUMAN" 4 1087.5502 1.35 109902 3451 2 1087.550951 544.7824 Far upstream element-binding protein 2 OS=Homo sapiens OX=9606 GN=KHSRP PE=1 SV=4 6.74 1298.1 - 1.20E+06 - - - 0.7163 - 1.859 0.367 - 346.5 1 2 0 0.0008 10 0 0 0 4.72E+07 3.50E+07 - - - 3.4821 0.9999 221125_WJC_METTL3_EV_vs_WT_F08.03456.03456.2 4.21E-08 22-Nov R.LTNGPSNGSSSR.Q sp|Q15007|FL2D_HUMAN 1 1175.5531 0.75 109907 3456 2 1175.552159 588.7838 Pre-mRNA-splicing regulator WTAP OS=Homo sapiens OX=9606 GN=WTAP PE=1 SV=2 9.75 1298.6 - 392593 - - - -0.7818 - 2.307 0.599 - 516.9 1 2 0 -0.0009 12 0 0 0 6.35E+06 8.44E+06 - - - 5.6644 1 221125_WJC_METTL3_EV_vs_WT_F08.03457.03457.2 1.25E-06 13/22 R.LTNGPSNGSSSR[166.11].Q sp|Q15007|FL2D_HUMAN 1 1185.5613 0.75 109908 3457 2 1185.562344 593.788 Pre-mRNA-splicing regulator WTAP OS=Homo sapiens OX=9606 GN=WTAP PE=1 SV=2 9.75 1298.8 - 348310 - - - 0.8401 - 2.488 0.592 - 560.6 1 2 0 0.001 12 0 0 0 6.35E+06 8.44E+06 - - - 5.8115 0.9998 221125_WJC_METTL3_EV_vs_WT_F08.03463.03463.2 0.000226 18-Sep R.GSPQQIDHAK.Q "sp|Q92945|FUBP2_HUMAN,tr|M0R3J3|M0R3J3_HUMAN,tr|M0R0C6|M0R0C6_HUMAN,tr|A0A087WTP3|A0A087WTP3_HUMAN" 4 1079.536 1.32 109912 3463 2 1079.534663 540.7753 Far upstream element-binding protein 2 OS=Homo sapiens OX=9606 GN=KHSRP PE=1 SV=4 6.74 1299.6 - 4.30E+06 - - - -1.2126 - 1.89 0.498 - 344.7 1 2 0 -0.0013 10 0 0 0 4.62E+07 3.50E+07 - - - 4.4957 0.986 221125_WJC_METTL3_EV_vs_WT_F08.03465.03465.2 0.0163 14-Oct S.PQQIDHAK[136.11].Q "sp|Q92945|FUBP2_HUMAN,tr|M0R3J3|M0R3J3_HUMAN,tr|M0R0C6|M0R0C6_HUMAN,tr|A0A087WTP3|A0A087WTP3_HUMAN" 4 943.4967 1.46 109914 3465 2 943.495596 472.7556 Far upstream element-binding protein 2 OS=Homo sapiens OX=9606 GN=KHSRP PE=1 SV=4 7.17 1299.7 - 4.49E+06 - - - -1.1479 - 2.249 0.366 - 343.4 1 1 0 -0.0011 8 0 0 0 4.56E+07 3.13E+07 - - - 4.1883 0.999 221125_WJC_METTL3_EV_vs_WT_F08.03469.03469.2 0.014 14-Aug R.SNDGNSYR.L "sp|O95299|NDUAA_HUMAN,tr|A0A7I2V4N8|A0A7I2V4N8_HUMAN,tr|A0A7I2V2N6|A0A7I2V2N6_HUMAN,tr|H7C1Y7|H7C1Y7_HUMAN,tr|A0A7I2V5B2|A0A7I2V5B2_HUMAN,tr|A0A7I2V419|A0A7I2V419_HUMAN,tr|A0A7I2V2W9|A0A7I2V2W9_HUMAN,tr|A0A7I2V2X3|A0A7I2V2X3_HUMAN,tr|A0A7I2YQU0|A0A7I2YQU0_HUMAN,tr|H7C2X4|H7C2X4_HUMAN,tr|A0A7I2V438|A0A7I2V438_HUMAN,tr|Q8N1B9|Q8N1B9_HUMAN,tr|E7ESZ7|E7ESZ7_HUMAN,tr|C9J6X0|C9J6X0_HUMAN,tr|A0A7I2V3H5|A0A7I2V3H5_HUMAN,tr|A0A7I2V5L0|A0A7I2V5L0_HUMAN,tr|A0A087WXC5|A0A087WXC5_HUMAN,tr|A0A7I2V458|A0A7I2V458_HUMAN,tr|A0A7I2V2F6|A0A7I2V2F6_HUMAN,tr|A0A7I2V594|A0A7I2V594_HUMAN,tr|A0A7I2V327|A0A7I2V327_HUMAN,tr|A0A7I2V5U7|A0A7I2V5U7_HUMAN,tr|A0A7I2V3D4|A0A7I2V3D4_HUMAN,tr|A0A7I2V2I6|A0A7I2V2I6_HUMAN" 24 911.3733 0.31 109918 3469 2 911.372543 456.6939 "NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 10, mitochondrial OS=Homo sapiens OX=9606 GN=NDUFA10 PE=1 SV=1" 5.55 1299.9 - 1.21E+06 - - - -0.8559 - 1.692 0.248 - 454.3 1 2 0 -0.0008 8 0 0 0 6.38E+07 2.06E+08 - - - 2.4586 0.9993 221125_WJC_METTL3_EV_vs_WT_F08.03471.03471.2 0.0129 14-Sep R.SNDGNSYR[166.11].L "sp|O95299|NDUAA_HUMAN,tr|A0A7I2V4N8|A0A7I2V4N8_HUMAN,tr|A0A7I2V2N6|A0A7I2V2N6_HUMAN,tr|H7C1Y7|H7C1Y7_HUMAN,tr|A0A7I2V5B2|A0A7I2V5B2_HUMAN,tr|A0A7I2V419|A0A7I2V419_HUMAN,tr|A0A7I2V2W9|A0A7I2V2W9_HUMAN,tr|A0A7I2V2X3|A0A7I2V2X3_HUMAN,tr|A0A7I2YQU0|A0A7I2YQU0_HUMAN,tr|H7C2X4|H7C2X4_HUMAN,tr|A0A7I2V438|A0A7I2V438_HUMAN,tr|Q8N1B9|Q8N1B9_HUMAN,tr|E7ESZ7|E7ESZ7_HUMAN,tr|C9J6X0|C9J6X0_HUMAN,tr|A0A7I2V3H5|A0A7I2V3H5_HUMAN,tr|A0A7I2V5L0|A0A7I2V5L0_HUMAN,tr|A0A087WXC5|A0A087WXC5_HUMAN,tr|A0A7I2V458|A0A7I2V458_HUMAN,tr|A0A7I2V2F6|A0A7I2V2F6_HUMAN,tr|A0A7I2V594|A0A7I2V594_HUMAN,tr|A0A7I2V327|A0A7I2V327_HUMAN,tr|A0A7I2V5U7|A0A7I2V5U7_HUMAN,tr|A0A7I2V3D4|A0A7I2V3D4_HUMAN,tr|A0A7I2V2I6|A0A7I2V2I6_HUMAN" 24 921.3816 0.27 109920 3471 2 921.380759 461.6981 "NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 10, mitochondrial OS=Homo sapiens OX=9606 GN=NDUFA10 PE=1 SV=1" 5.55 1300.2 - 942659 - - - -0.9052 - 1.95 0.239 - 589.4 1 2 0 -0.0008 8 0 0 0 6.40E+07 2.42E+08 - - - 2.8201 0.9998 221125_WJC_METTL3_EV_vs_WT_F08.03473.03473.2 3.10E-05 22-Jul K.ADQGDGPEGSGR[166.11].A sp|Q96RL1|UIMC1_HUMAN 1 1154.4828 1.58 109922 3473 2 1154.482128 578.2487 BRCA1-A complex subunit RAP80 OS=Homo sapiens OX=9606 GN=UIMC1 PE=1 SV=2 4.03 1300.3 - 192133 - - - -0.5509 - 1.513 0.563 - 170.7 1 2 0 -0.0006 12 0 0 0 1.11E+07 7.03E+06 - - - 4.2887 0.9998 221125_WJC_METTL3_EV_vs_WT_F08.03475.03475.2 0.00264 14-Sep R.QQTC[160.03]PTC[160.03]R.M sp|Q86TM6|SYVN1_HUMAN 1 1049.4382 1.17 109924 3475 2 1049.438031 525.7264 E3 ubiquitin-protein ligase synoviolin OS=Homo sapiens OX=9606 GN=SYVN1 PE=1 SV=2 8.07 1300.6 - 171805 - - - -0.2077 - 1.925 0.458 - 413.8 1 2 0 -0.0002 8 0 0 0 6.48E+06 5.53E+06 - - - 4.3989 0.9939 221125_WJC_METTL3_EV_vs_WT_F08.03477.03477.2 0.00161 16-Aug K.AEKDNAEIR.V sp|Q99832|TCPH_HUMAN 1 1044.52 0.2 109925 3477 2 1044.518886 523.2673 T-complex protein 1 subunit eta OS=Homo sapiens OX=9606 GN=CCT7 PE=1 SV=2 4.68 1300.8 - 808476 - - - -1.0541 - 1.647 0.359 - 234.8 1 2 1 -0.0011 9 0 0 0 2.19E+07 1.07E+08 - - - 3.1357 0.9998 221125_WJC_METTL3_EV_vs_WT_F08.03479.03479.2 0.000146 16-Sep R.SQSGGYSDR[166.11].S "sp|Q14011|CIRBP_HUMAN,tr|F6WMK9|F6WMK9_HUMAN,tr|K7EMY9|K7EMY9_HUMAN,tr|K7EQR7|K7EQR7_HUMAN,tr|K7EPM4|K7EPM4_HUMAN,tr|D6W5Y5|D6W5Y5_HUMAN" 6 965.4078 0.95 109926 3479 2 965.407025 483.7112 Cold-inducible RNA-binding protein OS=Homo sapiens OX=9606 GN=CIRBP PE=1 SV=1 5.55 1301.1 - 4.89E+06 - - - -0.8111 - 2.05 0.477 - 351.8 1 2 0 -0.0008 9 0 0 0 1.60E+09 1.69E+09 - - - 4.6406 0.9998 221125_WJC_METTL3_EV_vs_WT_F08.03480.03480.2 3.14E-05 16-Dec K.HTTDLDASK.L "sp|P17540|KCRS_HUMAN,sp|P12532|KCRU_HUMAN,tr|C9JSQ1|C9JSQ1_HUMAN,tr|D6RHV3|D6RHV3_HUMAN,tr|D6R998|D6R998_HUMAN,tr|C9JT96|C9JT96_HUMAN,tr|C9J8F6|C9J8F6_HUMAN,tr|F8WCN3|F8WCN3_HUMAN,tr|C9J6W7|C9J6W7_HUMAN" 9 986.4669 1.68 109927 3480 2 986.465712 494.2407 "Creatine kinase S-type, mitochondrial OS=Homo sapiens OX=9606 GN=CKMT2 PE=1 SV=2" 5.21 1301.1 - 4.13E+06 - - - -1.1931 - 2.218 0.472 - 401.2 1 2 0 -0.0012 9 0 0 0 9.77E+07 5.80E+07 - - - 4.8314 0.9813 221125_WJC_METTL3_EV_vs_WT_F08.03485.03485.2 0.386 12-Jun R.DSYSSSR[166.11].S "sp|Q96E39|RMXL1_HUMAN,sp|P38159|RBMX_HUMAN,tr|H3BUY5|H3BUY5_HUMAN" 3 810.3383 2.4 109932 3485 2 810.336601 406.1764 "RNA binding motif protein, X-linked-like-1 OS=Homo sapiens OX=9606 GN=RBMXL1 PE=1 SV=1" 5.84 1301.4 - 882638 - - - -2.1349 - 1.383 0.096 - 157.2 1 2 0 -0.0017 7 0 0 0 4.76E+07 1.99E+07 - - - 0.7769 0.9995 221125_WJC_METTL3_EV_vs_WT_F08.03487.03487.2 0.000462 16-Sep K.QQAQAEPER.H "sp|Q7Z3C6|ATG9A_HUMAN,tr|H7C152|H7C152_HUMAN" 2 1055.4996 1.64 109934 3487 2 1055.499317 528.7571 Autophagy-related protein 9A OS=Homo sapiens OX=9606 GN=ATG9A PE=1 SV=3 4.53 1301.6 - 651436 - - - -0.2549 - 1.664 0.347 - 439.5 1 2 0 -0.0003 9 0 0 0 6.59E+06 4.01E+06 - - - 3.0771 0.9987 221125_WJC_METTL3_EV_vs_WT_F08.03488.03488.2 0.0232 22-Sep K.ADQGDGPEGSGR.A sp|Q96RL1|UIMC1_HUMAN 1 1144.4745 0.6 109935 3488 2 1144.471102 573.2445 BRCA1-A complex subunit RAP80 OS=Homo sapiens OX=9606 GN=UIMC1 PE=1 SV=2 4.03 1301.8 - 228835 - - - -2.9638 - 1.778 0.411 - 299.6 1 2 0 -0.0034 12 0 0 0 3.48E+06 5.77E+06 - - - 3.5898 0.9988 221125_WJC_METTL3_EV_vs_WT_F08.03489.03489.2 0.00556 18-Aug R.LAHEDAEC[160.03]EK[136.11].L "sp|Q9UG63|ABCF2_HUMAN,tr|C9JZV3|C9JZV3_HUMAN,tr|C9JHK9|C9JHK9_HUMAN" 3 1208.5223 0.76 109936 3489 2 1208.518897 605.2684 ATP-binding cassette sub-family F member 2 OS=Homo sapiens OX=9606 GN=ABCF2 PE=1 SV=2 4.4 1301.9 - 159404 - - - -2.8175 - 1.746 0.397 - 202.8 1 2 0 -0.0034 10 0 0 0 7.01E+06 9.17E+06 - - - 3.5278 0.9994 221125_WJC_METTL3_EV_vs_WT_F08.03493.03493.2 0.0703 14-Aug R.VQDHIQSR.L "sp|Q16875|F263_HUMAN,sp|P16118|F261_HUMAN,tr|A0A1W2PR17|A0A1W2PR17_HUMAN,tr|I1Z9G3|I1Z9G3_HUMAN,tr|Q5W015|Q5W015_HUMAN,tr|F2Z2I2|F2Z2I2_HUMAN,tr|Q5VX20|Q5VX20_HUMAN" 7 981.4992 0.54 109938 3493 2 981.497113 491.7569 "6-phosphofructo-2-kinase\fructose-2,6-bisphosphatase 3 OS=Homo sapiens OX=9606 GN=PFKFB3 PE=1 SV=1" 6.71 1302.4 - 6.44E+06 - - - -2.1182 - 1.769 0.405 - 329 1 2 0 -0.0021 8 0 0 0 1.02E+08 1.88E+08 - - - 3.752 0.9955 221125_WJC_METTL3_EV_vs_WT_F08.03494.03494.2 0.00135 18-Oct K.ADK[136.11]LAEEHSS.- sp|P06576|ATPB_HUMAN 1 1093.5131 1.76 109939 3494 2 1093.511205 547.7638 "ATP synthase subunit beta, mitochondrial OS=Homo sapiens OX=9606 GN=ATP5F1B PE=1 SV=3" 4.65 1302.4 - 2.95E+06 - - - -1.7485 - 1.833 0.435 - 186.4 1 2 1 -0.0019 10 0 0 0 7.08E+07 4.01E+07 - - - 3.9447 0.9988 221125_WJC_METTL3_EV_vs_WT_F08.03498.03498.2 0.0447 16-Jun K.QQAQAEPER[166.11].H "sp|Q7Z3C6|ATG9A_HUMAN,tr|H7C152|H7C152_HUMAN" 2 1065.5079 1.87 109943 3498 2 1065.506505 533.7612 Autophagy-related protein 9A OS=Homo sapiens OX=9606 GN=ATG9A PE=1 SV=3 4.53 1302.8 - 457440 - - - -1.2679 - 1.297 0.36 - 129.8 1 2 0 -0.0014 9 0 0 0 7.34E+06 3.91E+06 - - - 2.4519 0.996 221125_WJC_METTL3_EV_vs_WT_F08.03499.03499.2 0.000106 18-Nov R.LAHEDAEC[160.03]EK.L "sp|Q9UG63|ABCF2_HUMAN,tr|C9JZV3|C9JZV3_HUMAN,tr|C9JHK9|C9JHK9_HUMAN" 3 1200.5081 0.76 109944 3499 2 1200.501015 601.2613 ATP-binding cassette sub-family F member 2 OS=Homo sapiens OX=9606 GN=ABCF2 PE=1 SV=2 4.4 1303 - 264096 - - - -5.9033 - 2.033 0.54 - 386.9 1 2 0 -0.0071 10 0 0 0 7.01E+06 9.17E+06 - - - 5.0077 0.8559 221125_WJC_METTL3_EV_vs_WT_F08.03501.03501.2 4.41 20-May R.EGGQTAPASTR.L "sp|P06396|GELS_HUMAN,tr|A0A0A0MS51|A0A0A0MS51_HUMAN,tr|A0A0A0MT01|A0A0A0MT01_HUMAN,tr|Q5T0H8|Q5T0H8_HUMAN" 4 1073.5102 2.11 109945 3501 2 1073.508074 537.7624 Gelsolin OS=Homo sapiens OX=9606 GN=GSN PE=1 SV=1 6.1 1303.2 - 957482 - - - -1.9348 - 0.977 0.061 - 83.3 2 2 0 -0.0021 11 0 0 0 1.47E+07 6.99E+06 - - - -0.7065 0.9884 221125_WJC_METTL3_EV_vs_WT_F08.03503.03503.2 0.000411 16-Jul R.EPGYKAEGK.Y "sp|Q9Y2W1|TR150_HUMAN,tr|A0A3B3ITZ9|A0A3B3ITZ9_HUMAN" 2 977.4818 2.41 109946 3503 2 977.479319 489.7482 Thyroid hormone receptor-associated protein 3 OS=Homo sapiens OX=9606 GN=THRAP3 PE=1 SV=2 6.24 1303.4 - 1.53E+07 - - - -2.5494 - 1.473 0.449 - 206.1 1 2 1 -0.0025 9 0 0 0 3.34E+08 1.38E+08 - - - 3.477 0.996 221125_WJC_METTL3_EV_vs_WT_F08.03505.03505.3 0.000469 Nov-36 R.LAHEDAEC[160.03]EK.L "sp|Q9UG63|ABCF2_HUMAN,tr|C9JZV3|C9JZV3_HUMAN,tr|C9JHK9|C9JHK9_HUMAN" 3 1200.5081 1.04 109948 3505 3 1200.499746 401.1766 ATP-binding cassette sub-family F member 2 OS=Homo sapiens OX=9606 GN=ABCF2 PE=1 SV=2 4.4 1303.5 - 4.12E+06 - - - -6.9604 - 2.063 0.445 - 125.4 1 2 0 -0.0084 10 0 0 0 5.01E+07 4.83E+07 - - - 5.6139 0.9898 221125_WJC_METTL3_EV_vs_WT_F08.03506.03506.3 0.0068 Nov-40 R.IVTDRETGSSK.G "sp|P19338|NUCL_HUMAN,tr|A0A7I2V699|A0A7I2V699_HUMAN,tr|A0A7I2V2U7|A0A7I2V2U7_HUMAN,tr|A0A7I2V3F3|A0A7I2V3F3_HUMAN,tr|A0A7I2V428|A0A7I2V428_HUMAN,tr|H7BY16|H7BY16_HUMAN,tr|A0A7I2V5M5|A0A7I2V5M5_HUMAN,tr|C9JLB1|C9JLB1_HUMAN" 8 1191.6095 0.92 109949 3506 3 1191.606026 398.2105 Nucleolin OS=Homo sapiens OX=9606 GN=NCL PE=1 SV=3 6.07 1303.5 - 3.42E+06 - - - -2.9414 - 1.765 0.314 - 128.9 1 2 1 -0.0035 11 0 0 0 3.04E+08 3.32E+08 - - - 3.6538 0.9998 221125_WJC_METTL3_EV_vs_WT_F08.03508.03508.2 0.038 14/16 K.HGLAHDEMK.S "sp|Q9Y2W1|TR150_HUMAN,tr|A0A3B3ITZ9|A0A3B3ITZ9_HUMAN" 2 1036.476 3.3 109951 3508 2 1036.473643 519.2453 Thyroid hormone receptor-associated protein 3 OS=Homo sapiens OX=9606 GN=THRAP3 PE=1 SV=2 5.99 1303.7 - 3.11E+06 - - - -2.2876 - 2.4 0.514 - 632.9 1 2 0 -0.0024 9 0 0 0 2.36E+08 7.13E+07 - - - 5.3694 0.9955 221125_WJC_METTL3_EV_vs_WT_F08.03509.03509.2 0.000105 15/20 R.IVTDR[166.11]ETGSSK[136.11].G "sp|P19338|NUCL_HUMAN,tr|A0A7I2V699|A0A7I2V699_HUMAN,tr|A0A7I2V2U7|A0A7I2V2U7_HUMAN,tr|A0A7I2V3F3|A0A7I2V3F3_HUMAN,tr|A0A7I2V428|A0A7I2V428_HUMAN,tr|H7BY16|H7BY16_HUMAN,tr|A0A7I2V5M5|A0A7I2V5M5_HUMAN,tr|C9JLB1|C9JLB1_HUMAN" 8 1209.632 0.98 109952 3509 2 1209.628481 605.8233 Nucleolin OS=Homo sapiens OX=9606 GN=NCL PE=1 SV=3 6.07 1303.8 - 818326 - - - -2.91 - 2.41 0.527 - 676.5 1 2 1 -0.0035 11 0 0 0 6.85E+07 7.00E+07 - - - 5.3119 0.9966 221125_WJC_METTL3_EV_vs_WT_F08.03510.03510.2 0.00103 15/20 R.IVTDRETGSSK.G "sp|P19338|NUCL_HUMAN,tr|A0A7I2V699|A0A7I2V699_HUMAN,tr|A0A7I2V2U7|A0A7I2V2U7_HUMAN,tr|A0A7I2V3F3|A0A7I2V3F3_HUMAN,tr|A0A7I2V428|A0A7I2V428_HUMAN,tr|H7BY16|H7BY16_HUMAN,tr|A0A7I2V5M5|A0A7I2V5M5_HUMAN,tr|C9JLB1|C9JLB1_HUMAN" 8 1191.6095 0.98 109953 3510 2 1191.606693 596.812 Nucleolin OS=Homo sapiens OX=9606 GN=NCL PE=1 SV=3 6.07 1303.9 - 491067 - - - -2.3817 - 2.634 0.46 - 600.6 1 2 1 -0.0028 11 0 0 0 6.85E+07 7.00E+07 - - - 5.0577 0.9993 221125_WJC_METTL3_EV_vs_WT_F08.03513.03513.2 0.00407 16-Dec R.VHELEQQNK.V sp|P07196|NFL_HUMAN 1 1123.5622 1.86 109954 3513 2 1123.559233 562.7884 Neurofilament light polypeptide OS=Homo sapiens OX=9606 GN=NEFL PE=1 SV=3 5.4 1304.3 - 2.30E+06 - - - -2.6282 - 1.912 0.433 - 661.8 1 2 0 -0.003 9 0 0 0 9.47E+07 5.08E+07 - - - 4.1133 0.9833 221125_WJC_METTL3_EV_vs_WT_F08.03515.03515.2 0.729 14-Oct K.RNSTIPTK.Q "sp|P0DMV8|HS71A_HUMAN,sp|P34931|HS71L_HUMAN,sp|P0DMV9|HS71B_HUMAN,tr|Q53FA3|Q53FA3_HUMAN,tr|V9GZ37|V9GZ37_HUMAN,tr|A0A0G2JIW1|A0A0G2JIW1_HUMAN" 6 915.5138 0.14 109956 3515 2 915.511673 458.7642 Heat shock 70 kDa protein 1A OS=Homo sapiens OX=9606 GN=HSPA1A PE=1 SV=1 11 1304.5 - 3.22E+06 - - - -2.3014 - 1.761 0.026 - 572 1 2 0 -0.0021 8 0 0 0 2.01E+08 1.49E+09 - - - 0.939 0.9996 221125_WJC_METTL3_EV_vs_WT_F08.03516.03516.2 0.000147 16-Oct R.VHELEQQNK[136.11].V sp|P07196|NFL_HUMAN 1 1131.5764 1.86 109957 3516 2 1131.574024 566.7955 Neurofilament light polypeptide OS=Homo sapiens OX=9606 GN=NEFL PE=1 SV=3 5.4 1304.5 - 1.38E+06 - - - -2.0874 - 1.798 0.494 - 425.4 1 2 0 -0.0024 9 0 0 0 9.47E+07 5.08E+07 - - - 4.3862 0.9938 221125_WJC_METTL3_EV_vs_WT_F08.03521.03521.2 0.125 14-Aug R.NTVVPTK[136.11]K[136.11].S "sp|P11021|BIP_HUMAN,tr|A0A7P0TB36|A0A7P0TB36_HUMAN,tr|A0A7P0TAI0|A0A7P0TAI0_HUMAN" 3 901.5568 0.6 109960 3521 2 901.554093 451.7857 Endoplasmic reticulum chaperone BiP OS=Homo sapiens OX=9606 GN=HSPA5 PE=1 SV=2 10 1305 - 5.37E+06 - - - -2.966 - 1.609 0.216 - 314.9 1 2 0 -0.0027 8 0 0 0 1.66E+08 2.78E+08 - - - 2.07 1 221125_WJC_METTL3_EV_vs_WT_F08.03522.03522.2 0.000318 14/16 K.HGLAHDEMK[136.11].S "sp|Q9Y2W1|TR150_HUMAN,tr|A0A3B3ITZ9|A0A3B3ITZ9_HUMAN" 2 1044.4902 3.3 109961 3522 2 1044.485513 523.2524 Thyroid hormone receptor-associated protein 3 OS=Homo sapiens OX=9606 GN=THRAP3 PE=1 SV=2 5.99 1305.1 - 4.10E+06 - - - -4.5008 - 2.435 0.572 - 655 1 2 0 -0.0047 9 0 0 0 2.36E+08 7.13E+07 - - - 5.839 0.996 221125_WJC_METTL3_EV_vs_WT_F08.03534.03534.2 0.00509 14-Aug R.NTVVPTKK.S "sp|P11021|BIP_HUMAN,tr|A0A7P0TB36|A0A7P0TB36_HUMAN,tr|A0A7P0TAI0|A0A7P0TAI0_HUMAN" 3 885.5284 0.6 109969 3534 2 885.526098 443.7715 Endoplasmic reticulum chaperone BiP OS=Homo sapiens OX=9606 GN=HSPA5 PE=1 SV=2 10 1306.5 - 4.64E+06 - - - -2.5623 - 1.714 0.207 - 361.3 1 2 0 -0.0023 8 0 0 0 1.67E+08 2.78E+08 - - - 2.1943 0.9677 221125_WJC_METTL3_EV_vs_WT_F08.03535.03535.2 0.237 14-Oct K.LK[136.11]EDK[136.11]LEK[136.11].Q "sp|Q8ND56|LS14A_HUMAN,sp|Q07866|KLC1_HUMAN,tr|G3V5R9|G3V5R9_HUMAN,tr|G3V3H3|G3V3H3_HUMAN,tr|G3V2P7|G3V2P7_HUMAN,tr|F8W6L3|F8W6L3_HUMAN,tr|E7EVH7|E7EVH7_HUMAN,tr|A0A140TA76|A0A140TA76_HUMAN,tr|K7EMZ9|K7EMZ9_HUMAN,tr|G3V2E7|G3V2E7_HUMAN,tr|G5E9S8|G5E9S8_HUMAN" 11 1025.6183 0.96 109970 3535 2 1025.615178 513.8164 Protein LSM14 homolog A OS=Homo sapiens OX=9606 GN=LSM14A PE=1 SV=3 6.18 1306.5 - 3.84E+06 - - - -3.0547 - 2.008 0.222 - 245.8 1 2 2 -0.0031 8 0 0 0 2.27E+08 2.36E+08 - - - 2.7822 0.8236 221125_WJC_METTL3_EV_vs_WT_F08.03545.03545.2 0.0101 14/18 L.VTDRETGSSK.G "sp|P19338|NUCL_HUMAN,tr|A0A7I2V699|A0A7I2V699_HUMAN,tr|A0A7I2V2U7|A0A7I2V2U7_HUMAN,tr|A0A7I2V3F3|A0A7I2V3F3_HUMAN,tr|A0A7I2V428|A0A7I2V428_HUMAN,tr|H7BY16|H7BY16_HUMAN,tr|A0A7I2V5M5|A0A7I2V5M5_HUMAN,tr|C9JLB1|C9JLB1_HUMAN" 8 1078.5255 2.52 109978 3545 2 1078.52336 540.27 Nucleolin OS=Homo sapiens OX=9606 GN=NCL PE=1 SV=3 6.04 1307.6 - 2.47E+06 - - - -1.9536 - 2.711 0.359 - 429.7 1 1 1 -0.0021 10 0 0 0 4.28E+07 1.70E+07 - - - 4.4757 0.9998 221125_WJC_METTL3_EV_vs_WT_F08.03553.03553.2 2.16E-05 18-Nov K.SSENQGTVER[166.11].G sp|Q5JSZ5|PRC2B_HUMAN 1 1115.5083 1.78 109984 3553 2 1115.506631 558.7614 Protein PRRC2B OS=Homo sapiens OX=9606 GN=PRRC2B PE=1 SV=2 4.53 1308.5 - 3.27E+06 - - - -1.4514 - 2.093 0.46 - 589 1 2 0 -0.0016 10 0 0 0 2.19E+08 1.24E+08 - - - 4.4997 0.9982 221125_WJC_METTL3_EV_vs_WT_F08.03558.03558.2 0.00444 18-Aug K.EEGKPLQQEK.E "sp|P07197|NFM_HUMAN,tr|E7ESP9|E7ESP9_HUMAN" 2 1184.6037 3.19 109987 3558 2 1184.601096 593.3091 Neurofilament medium polypeptide OS=Homo sapiens OX=9606 GN=NEFM PE=1 SV=3 4.79 1309.1 - 683185 - - - -2.2126 - 1.403 0.361 - 151.7 1 2 0 -0.0026 10 0 0 0 1.77E+07 5.56E+06 - - - 2.6517 0.9816 221125_WJC_METTL3_EV_vs_WT_F08.03559.03559.2 0.0334 18-Jul K.EEGK[136.11]PLQQEK[136.11].E "sp|P07197|NFM_HUMAN,tr|E7ESP9|E7ESP9_HUMAN" 2 1200.6321 3.18 109988 3559 2 1200.627112 601.3233 Neurofilament medium polypeptide OS=Homo sapiens OX=9606 GN=NEFM PE=1 SV=3 4.79 1309.2 - 314757 - - - -4.1686 - 1.347 0.273 - 118.7 1 2 0 -0.005 10 0 0 0 1.77E+07 5.56E+06 - - - 1.8873 0.9983 221125_WJC_METTL3_EV_vs_WT_F08.03564.03564.2 1.41 14-Oct R.R[166.11]YPSGEER[166.11].C "sp|O00217|NDUS8_HUMAN,tr|E9PPW7|E9PPW7_HUMAN,tr|F8W9K7|F8W9K7_HUMAN,tr|H0YDT4|H0YDT4_HUMAN,tr|E9PKH6|E9PKH6_HUMAN,tr|E9PN51|E9PN51_HUMAN" 6 1012.4841 2.16 109991 3564 2 1012.481375 507.2493 "NADH dehydrogenase [ubiquinone] iron-sulfur protein 8, mitochondrial OS=Homo sapiens OX=9606 GN=NDUFS8 PE=1 SV=1" 6.14 1309.7 - 804294 - - - -2.6894 - 2.113 0.237 - 324.8 1 2 0 -0.0027 8 0 0 0 3.43E+07 1.59E+07 - - - 3.0469 0.9988 221125_WJC_METTL3_EV_vs_WT_F08.03568.03568.2 0.00231 20-Jul K.QGGSPDEPDSK[136.11].A "sp|Q9ULX6|AKP8L_HUMAN,tr|A0A7P0T9N5|A0A7P0T9N5_HUMAN,tr|A0A7P0TAD3|A0A7P0TAD3_HUMAN,tr|V9GZ50|V9GZ50_HUMAN,tr|A0A7P0TBP0|A0A7P0TBP0_HUMAN,tr|A0A7P0TAJ5|A0A7P0TAJ5_HUMAN,tr|A0A7P0TAE3|A0A7P0TAE3_HUMAN,tr|A0A7P0T847|A0A7P0T847_HUMAN" 8 1123.4873 0.64 109993 3568 2 1123.484326 562.7509 A-kinase anchor protein 8-like OS=Homo sapiens OX=9606 GN=AKAP8L PE=1 SV=4 4.03 1310.2 - 1.58E+06 - - - -2.6444 - 1.628 0.418 - 195.8 1 2 0 -0.003 11 0 0 0 2.47E+07 3.87E+07 - - - 3.4458 0.891 221125_WJC_METTL3_EV_vs_WT_F08.03576.03576.2 0.349 16-Oct L.KGTNESLER.Q "sp|P08670|VIME_HUMAN,tr|B0YJC5|B0YJC5_HUMAN,tr|B0YJC4|B0YJC4_HUMAN" 3 1032.52 1.84 109997 3576 2 1032.517742 517.2673 Vimentin OS=Homo sapiens OX=9606 GN=VIM PE=1 SV=4 6.14 1311.1 - 1.57E+06 - - - -2.1743 - 1.85 0.232 - 345.7 1 1 0 -0.0022 9 0 0 0 3.53E+07 1.92E+07 - - - 2.5336 0.9993 221125_WJC_METTL3_EV_vs_WT_F08.03582.03582.2 0.00346 14-Sep K.NSEEQYNK[136.11].L sp|P42285|MTREX_HUMAN 1 1018.4447 0.64 110003 3582 2 1018.443142 510.2296 Exosome RNA helicase MTR4 OS=Homo sapiens OX=9606 GN=MTREX PE=1 SV=3 4.53 1311.7 - 771906 - - - -1.5337 - 1.515 0.38 - 275.7 1 2 0 -0.0016 8 0 0 0 2.43E+07 3.81E+07 - - - 3.1001 0.9278 221125_WJC_METTL3_EV_vs_WT_F08.03583.03583.2 0.0174 16-Aug K.GKTPQVGDR.V "sp|Q8IX12|CCAR1_HUMAN,tr|F5H2E6|F5H2E6_HUMAN,tr|A0A0C4DGG8|A0A0C4DGG8_HUMAN,tr|F5H3E1|F5H3E1_HUMAN" 4 956.5039 1.15 110004 3583 2 956.499441 479.2592 Cell division cycle and apoptosis regulator protein 1 OS=Homo sapiens OX=9606 GN=CCAR1 PE=1 SV=2 8.75 1311.7 - 1.33E+06 - - - -4.7067 - 1.703 0.347 - 259.3 1 2 1 -0.0045 9 0 0 0 1.04E+08 9.05E+07 - - - 3.1428 0.9941 221125_WJC_METTL3_EV_vs_WT_F08.03586.03586.2 6.46E-06 18-Aug R.SSGGGYSGDR.S "sp|Q92804|RBP56_HUMAN,tr|A0A075B7F4|A0A075B7F4_HUMAN" 2 941.3839 0.88 110005 3586 2 941.377456 471.6992 TATA-binding protein-associated factor 2N OS=Homo sapiens OX=9606 GN=TAF15 PE=1 SV=1 5.55 1312.1 - 8.94E+06 - - - -6.8325 - 1.942 0.632 - 273.8 1 2 0 -0.0064 10 0 0 0 1.71E+08 1.95E+08 - - - 5.5596 0.9992 221125_WJC_METTL3_EV_vs_WT_F08.03587.03587.2 0.0002 20-Sep K.GSSGLGGGSSR.T "sp|Q04695|K1C17_HUMAN,tr|K7EPJ9|K7EPJ9_HUMAN" 2 920.4312 5.51 110006 3587 2 920.429259 461.2229 "Keratin, type I cytoskeletal 17 OS=Homo sapiens OX=9606 GN=KRT17 PE=1 SV=2" 9.75 1312.2 - 7.13E+06 - - - -2.0784 - 1.694 0.405 - 218.6 1 2 0 -0.0019 11 0 0 0 4.33E+08 7.86E+07 - - - 3.4576 0.9996 221125_WJC_METTL3_EV_vs_WT_F08.03590.03590.2 0.00155 12-Aug R.SNQWHGR[166.11].S "sp|Q9BTL3|RAMAC_HUMAN,tr|A0A3B3IU46|A0A3B3IU46_HUMAN" 2 893.4132 0.77 110009 3590 2 893.412466 447.7139 RNA guanine-N7 methyltransferase activating subunit OS=Homo sapiens OX=9606 GN=RAMAC PE=1 SV=1 9.49 1312.3 - 1.56E+06 - - - -0.7858 - 1.7 0.375 - 445.2 1 2 0 -0.0007 7 0 0 0 2.38E+07 3.11E+07 - - - 3.4919 0.999 221125_WJC_METTL3_EV_vs_WT_F08.03591.03591.2 0.0166 18-Sep R.GQTNVGQDGR[166.11].Q "sp|Q5VIR6|VPS53_HUMAN,tr|A0A7P0Z4Q7|A0A7P0Z4Q7_HUMAN,tr|A0A7P0TAE0|A0A7P0TAE0_HUMAN,tr|A0A7P0T8V9|A0A7P0T8V9_HUMAN,tr|A0A7P0TB80|A0A7P0TB80_HUMAN,tr|A0A7P0Z461|A0A7P0Z461_HUMAN,tr|A0A7P0T8K1|A0A7P0T8K1_HUMAN,tr|A0A7P0T8S5|A0A7P0T8S5_HUMAN,tr|A0A7P0TA41|A0A7P0TA41_HUMAN,tr|A0A7P0T8P7|A0A7P0T8P7_HUMAN,tr|A0A7P0Z4M8|A0A7P0Z4M8_HUMAN,tr|I3L4P9|I3L4P9_HUMAN,tr|F6VX93|F6VX93_HUMAN,tr|A0A7P0TBJ8|A0A7P0TBJ8_HUMAN,tr|A0A7P0T9V8|A0A7P0T9V8_HUMAN,tr|A0A7P0T9Z7|A0A7P0T9Z7_HUMAN,tr|E7EVT8|E7EVT8_HUMAN,tr|A0A7P0T9B6|A0A7P0T9B6_HUMAN,tr|I3L0S6|I3L0S6_HUMAN,tr|A0A7P0T8I9|A0A7P0T8I9_HUMAN,tr|A0A7P0T874|A0A7P0T874_HUMAN,tr|A0A7P0T7U9|A0A7P0T7U9_HUMAN" 22 1040.4875 0.58 110010 3591 2 1040.485263 521.251 Vacuolar protein sorting-associated protein 53 homolog OS=Homo sapiens OX=9606 GN=VPS53 PE=1 SV=2 5.84 1312.5 - 431308 - - - -2.1067 - 1.721 0.361 - 122.1 1 2 0 -0.0022 10 0 0 0 4.51E+06 7.74E+06 - - - 3.2221 0.9975 221125_WJC_METTL3_EV_vs_WT_F08.03593.03593.2 0.000162 18-Jun K.LHC[160.03]TPGDGQR[166.11].F "sp|Q6L8Q7|PDE12_HUMAN,tr|F6T1Q0|F6T1Q0_HUMAN" 2 1149.5225 1.55 110012 3593 2 1149.518809 575.7685 "2',5'-phosphodiesterase 12 OS=Homo sapiens OX=9606 GN=PDE12 PE=1 SV=2" 6.74 1312.7 - 228382 - - - -3.177 - 1.445 0.401 - 149.2 1 2 0 -0.0037 10 0 0 0 9.28E+06 5.99E+06 - - - 3.0291 0.9944 221125_WJC_METTL3_EV_vs_WT_F08.03595.03595.2 0.169 18-Jul R.SAVPPGADKK.A "sp|P46783|RS10_HUMAN,tr|F6U211|F6U211_HUMAN,tr|A0A1W2PQS6|A0A1W2PQS6_HUMAN,tr|A0A2R8YFH6|A0A2R8YFH6_HUMAN,tr|A0A2R8Y7H1|A0A2R8Y7H1_HUMAN,tr|S4R435|S4R435_HUMAN" 6 968.5291 1.05 110013 3595 2 968.527343 485.2718 40S ribosomal protein S10 OS=Homo sapiens OX=9606 GN=RPS10 PE=1 SV=1 8.31 1313.1 - 1.13E+06 - - - -1.8089 - 1.46 0.188 - 190.7 1 2 0 -0.0018 10 0 0 0 6.48E+07 6.16E+07 - - - 1.4853 0.9999 221125_WJC_METTL3_EV_vs_WT_F08.03597.03597.3 6.69E-05 Oct-36 K.LHC[160.03]TPGDGQR[166.11].F "sp|Q6L8Q7|PDE12_HUMAN,tr|F6T1Q0|F6T1Q0_HUMAN" 2 1149.5225 0.65 110014 3597 3 1149.519323 384.1814 "2',5'-phosphodiesterase 12 OS=Homo sapiens OX=9606 GN=PDE12 PE=1 SV=2" 6.74 1313.3 - 1.30E+06 - - - -2.7298 - 2.169 0.469 - 222 1 2 0 -0.0031 10 0 0 0 1.78E+07 2.74E+07 - - - 6.0292 0.9969 221125_WJC_METTL3_EV_vs_WT_F08.03598.03598.2 0.00484 14-Aug K.NSEEQYNK.L sp|P42285|MTREX_HUMAN 1 1010.4305 0.71 110015 3598 2 1010.427361 506.2225 Exosome RNA helicase MTR4 OS=Homo sapiens OX=9606 GN=MTREX PE=1 SV=3 4.53 1313.3 - 1.55E+06 - - - -3.1106 - 1.493 0.342 - 322.4 1 2 0 -0.0031 8 0 0 0 2.28E+07 3.22E+07 - - - 2.7748 0.8138 221125_WJC_METTL3_EV_vs_WT_F08.03599.03599.2 0.0677 14-Jul R.NTTIPTK[136.11]K[136.11].S "sp|P38646|GRP75_HUMAN,tr|A0A7I2V2S7|A0A7I2V2S7_HUMAN,tr|A0A7I2V2G2|A0A7I2V2G2_HUMAN,tr|A0A7I2YQB2|A0A7I2YQB2_HUMAN,tr|D6RCD7|D6RCD7_HUMAN" 5 917.5517 0.45 110016 3599 2 917.545447 459.7831 "Stress-70 protein, mitochondrial OS=Homo sapiens OX=9606 GN=HSPA9 PE=1 SV=2" 10 1313.4 - 2.29E+06 - - - -6.7953 - 1.546 0.139 - 243.7 1 2 0 -0.0062 8 0 0 0 4.08E+08 9.12E+08 - - - 1.3797 1 221125_WJC_METTL3_EV_vs_WT_F08.03602.03602.3 2.95E-08 17/40 R.QAADEDDKGMR.S sp|P48634|PRC2A_HUMAN 1 1234.5248 1.37 110019 3602 3 1234.521806 412.5155 Protein PRRC2A OS=Homo sapiens OX=9606 GN=PRRC2A PE=1 SV=3 4.23 1313.7 - 860365 - - - -2.4374 - 3.031 0.636 - 572.6 1 2 1 -0.003 11 0 0 0 1.81E+07 1.32E+07 - - - 8.7801 0.9995 221125_WJC_METTL3_EV_vs_WT_F08.03603.03603.2 0.00387 12-Jul R.SHQDFSR.Q sp|Q07065|CKAP4_HUMAN 1 875.3886 1.42 110020 3603 2 875.387465 438.7016 Cytoskeleton-associated protein 4 OS=Homo sapiens OX=9606 GN=CKAP4 PE=1 SV=2 6.46 1313.8 - 837177 - - - -1.2726 - 1.445 0.427 - 303.8 1 2 0 -0.0011 7 0 0 0 1.08E+07 7.61E+06 - - - 3.3608 0.999 221125_WJC_METTL3_EV_vs_WT_F08.03605.03605.2 0.0776 16-Aug R.AGR[166.11]PQYDTK[136.11].G "sp|O75643|U520_HUMAN,tr|A0A494C1A5|A0A494C1A5_HUMAN" 2 1052.537 2.11 110021 3605 2 1052.536241 527.2758 U5 small nuclear ribonucleoprotein 200 kDa helicase OS=Homo sapiens OX=9606 GN=SNRNP200 PE=1 SV=2 8.63 1314 - 1.20E+06 - - - -0.7002 - 1.637 0.267 - 302.2 1 2 0 -0.0007 9 0 0 0 3.70E+07 1.75E+07 - - - 2.4387 0.9996 221125_WJC_METTL3_EV_vs_WT_F08.03608.03608.2 0.000232 20-Oct R.GSNLNSSGANR.T sp|Q6ZU65|UBN2_HUMAN 1 1075.5006 1.8 110023 3608 2 1075.498775 538.7576 Ubinuclein-2 OS=Homo sapiens OX=9606 GN=UBN2 PE=1 SV=2 9.75 1314.3 - 2.86E+06 - - - -1.7424 - 1.967 0.41 - 305.7 1 2 0 -0.0019 11 0 0 0 5.50E+07 3.05E+07 - - - 3.8988 1 221125_WJC_METTL3_EV_vs_WT_F08.03609.03609.2 7.83E-07 13/20 T.QSVGGDSSADR[166.11].L "sp|Q86U44|MTA70_HUMAN,tr|H0YFV6|H0YFV6_HUMAN" 2 1087.4769 0.02 110024 3609 2 1087.474953 544.7458 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 4.21 1314.3 - 3.08E+06 - - - -1.8364 - 2.558 0.602 - 743.2 1 1 0 -0.002 11 0 0 0 1.28E+07 6.93E+08 - - - 6.0276 0.9993 221125_WJC_METTL3_EV_vs_WT_F08.03611.03611.3 0.000347 Dec-44 K.VIGANKNQEEEK.S "sp|Q9Y2W1|TR150_HUMAN,tr|A0A3B3ITZ9|A0A3B3ITZ9_HUMAN" 2 1357.6838 2.81 110026 3611 3 1357.681081 453.5685 Thyroid hormone receptor-associated protein 3 OS=Homo sapiens OX=9606 GN=THRAP3 PE=1 SV=2 4.79 1314.4 - 1.84E+06 - - - -1.9717 - 2.277 0.406 - 158.6 1 2 1 -0.0027 12 0 0 0 1.64E+07 5.82E+06 - - - 5.3466 1 221125_WJC_METTL3_EV_vs_WT_F08.03613.03613.3 7.43E-09 17/40 R.QAADEDDK[136.11]GMR[166.11].S sp|P48634|PRC2A_HUMAN 1 1252.5473 1.23 110028 3613 3 1252.544285 418.523 Protein PRRC2A OS=Homo sapiens OX=9606 GN=PRRC2A PE=1 SV=3 4.23 1314.6 - 1.02E+06 - - - -2.3951 - 2.988 0.632 - 605.7 1 2 1 -0.003 11 0 0 0 1.53E+07 1.24E+07 - - - 8.6949 0.9975 221125_WJC_METTL3_EV_vs_WT_F08.03621.03621.2 0.124 16-Jul K.RSAPSGPVR.S "sp|P38159|RBMX_HUMAN,tr|H3BUY5|H3BUY5_HUMAN,tr|H3BT71|H3BT71_HUMAN,tr|H0Y6E7|H0Y6E7_HUMAN" 4 925.5094 2.21 110033 3621 2 925.507988 463.762 "RNA-binding motif protein, X chromosome OS=Homo sapiens OX=9606 GN=RBMX PE=1 SV=3" 12 1315.5 - 1.71E+06 - - - -1.4857 - 1.512 0.234 - 82.5 1 2 0 -0.0014 9 0 0 0 2.73E+07 1.23E+07 - - - 1.965 0.9981 221125_WJC_METTL3_EV_vs_WT_F08.03622.03622.2 0.000667 16-Oct R.STTNKLETR.R sp|Q13835|PKP1_HUMAN 1 1048.5513 11.32 110034 3622 2 1048.551261 525.2829 Plakophilin-1 OS=Homo sapiens OX=9606 GN=PKP1 PE=1 SV=2 8.46 1315.6 - 1.68E+06 - - - -0.0248 - 2.186 0.41 - 420.4 1 2 1 0 9 0 0 0 3.25E+07 2.87E+06 - - - 4.3318 0.9998 221125_WJC_METTL3_EV_vs_WT_F08.03624.03624.2 9.59E-05 16-Oct K.TEVC[160.03]QTC[160.03]SK.L "sp|Q9NW64|RBM22_HUMAN,tr|E5RJW4|E5RJW4_HUMAN,tr|E5RHA8|E5RHA8_HUMAN" 3 1111.4638 0.96 110036 3624 2 1111.461605 556.7392 Pre-mRNA-splicing factor RBM22 OS=Homo sapiens OX=9606 GN=RBM22 PE=1 SV=1 5.66 1315.8 - 1.06E+06 - - - -1.9704 - 1.903 0.557 - 480.9 1 2 0 -0.0022 9 0 0 0 2.02E+07 2.11E+07 - - - 5.0158 0.9993 221125_WJC_METTL3_EV_vs_WT_F08.03625.03625.2 0.0964 18-Nov R.MEEESQSQGR[166.11].D "sp|Q14683|SMC1A_HUMAN,tr|G8JLG1|G8JLG1_HUMAN" 2 1189.4909 1.02 110037 3625 2 1189.487331 595.7527 Structural maintenance of chromosomes protein 1A OS=Homo sapiens OX=9606 GN=SMC1A PE=1 SV=2 4.25 1315.9 - 456168 - - - -2.9878 - 2.454 0.38 - 661.8 1 2 0 -0.0036 10 0 0 0 1.71E+07 1.68E+07 - - - 4.3524 0.9989 221125_WJC_METTL3_EV_vs_WT_F08.03631.03631.2 0.318 14-Nov R.RTIAPC[160.03]QK.A "sp|P38646|GRP75_HUMAN,tr|H0Y8K0|H0Y8K0_HUMAN,tr|A0A7I2V2S7|A0A7I2V2S7_HUMAN,tr|A0A7I2V2G2|A0A7I2V2G2_HUMAN,tr|A0A7I2V3F7|A0A7I2V3F7_HUMAN,tr|A0A7I2YQB2|A0A7I2YQB2_HUMAN,tr|D6RCD7|D6RCD7_HUMAN" 7 972.5175 0.4 110041 3631 2 972.518041 487.266 "Stress-70 protein, mitochondrial OS=Homo sapiens OX=9606 GN=HSPA9 PE=1 SV=2" 9.51 1316.6 - 2.24E+06 - - - 0.5717 - 1.831 0.207 - 490.8 1 2 0 0.0006 8 0 0 0 7.38E+07 1.83E+08 - - - 2.394 0.9995 221125_WJC_METTL3_EV_vs_WT_F08.03635.03635.2 2.70E-05 18-Oct R.MEEESQSQGR.D "sp|Q14683|SMC1A_HUMAN,tr|G8JLG1|G8JLG1_HUMAN" 2 1179.4826 1.02 110044 3635 2 1179.479155 590.7486 Structural maintenance of chromosomes protein 1A OS=Homo sapiens OX=9606 GN=SMC1A PE=1 SV=2 4.25 1317 - 843423 - - - -2.9335 - 2.206 0.496 - 421.9 1 2 0 -0.0035 10 0 0 0 1.71E+07 1.68E+07 - - - 4.9118 0.9989 221125_WJC_METTL3_EV_vs_WT_F08.03637.03637.2 0.00122 16-Jul R.DGEQTEPSR[166.11].M "sp|Q9Y618|NCOR2_HUMAN,tr|C9J7T7|C9J7T7_HUMAN,tr|C9JE98|C9JE98_HUMAN,tr|H7C184|H7C184_HUMAN,tr|C9J0Q5|C9J0Q5_HUMAN,tr|A0A384DVL6|A0A384DVL6_HUMAN" 6 1027.4446 4.41 110046 3637 2 1027.44167 514.7296 Nuclear receptor corepressor 2 OS=Homo sapiens OX=9606 GN=NCOR2 PE=1 SV=3 4.14 1317.2 - 349283 - - - -2.8391 - 1.579 0.447 - 175.8 1 2 0 -0.0029 9 0 0 0 4.26E+07 9.65E+06 - - - 3.6631 0.9998 221125_WJC_METTL3_EV_vs_WT_F08.03647.03647.2 0.000351 14/20 R.IAGQVAAANKK.H "sp|P39019|RS19_HUMAN,tr|A0A075B6E2|A0A075B6E2_HUMAN" 2 1069.6244 1.18 110052 3647 2 1069.622901 535.8195 40S ribosomal protein S19 OS=Homo sapiens OX=9606 GN=RPS19 PE=1 SV=2 10 1318.5 - 1.16E+06 - - - -1.3949 - 2.269 0.427 - 777.6 1 2 0 -0.0015 11 0 0 0 7.89E+07 6.67E+07 - - - 4.4109 0.9945 221125_WJC_METTL3_EV_vs_WT_F08.03660.03660.2 0.00114 22-Aug K.EGTAPSENGETK[136.11].A "sp|Q15651|HMGN3_HUMAN,tr|A0A087WZE9|A0A087WZE9_HUMAN" 2 1226.5506 0.36 110060 3660 2 1226.545434 614.2826 High mobility group nucleosome-binding domain-containing protein 3 OS=Homo sapiens OX=9606 GN=HMGN3 PE=1 SV=2 4.25 1320.2 - 344441 - - - -4.2322 - 1.59 0.374 - 169.1 1 2 0 -0.0052 12 0 0 0 4.14E+06 1.15E+07 - - - 3.0219 0.9977 221125_WJC_METTL3_EV_vs_WT_F08.03661.03661.2 0.0628 16-Aug K.SQRPEEEVK.S "sp|P82094|TMF1_HUMAN,tr|F8WF45|F8WF45_HUMAN,tr|A0A2R8Y7M0|A0A2R8Y7M0_HUMAN" 3 1100.5462 2.5 110061 3661 2 1100.543965 551.2804 TATA element modulatory factor OS=Homo sapiens OX=9606 GN=TMF1 PE=1 SV=2 4.78 1320.3 - 359899 - - - -2.0326 - 1.734 0.231 - 290.1 1 2 0 -0.0022 9 0 0 0 7.54E+06 3.02E+06 - - - 2.3389 0.9839 221125_WJC_METTL3_EV_vs_WT_F08.03671.03671.2 0.00223 18-Sep F.GSDQSENVDR.G "sp|Q9UII2|ATIF1_HUMAN,tr|A0A0B4J230|A0A0B4J230_HUMAN" 2 1105.4636 0.79 110067 3671 2 1105.46531 553.7391 "ATPase inhibitor, mitochondrial OS=Homo sapiens OX=9606 GN=ATP5IF1 PE=1 SV=1" 4.03 1321.5 - 1.11E+06 - - - 1.5514 - 2.057 0.461 - 399.7 1 1 0 0.0017 10 0 0 0 1.36E+07 1.72E+07 - - - 4.4586 0.8289 221125_WJC_METTL3_EV_vs_WT_F08.03673.03673.2 0.993 14-Jun K.VSPTAK[136.11]TK[136.11].S "sp|Q17RW2|COOA1_HUMAN,tr|F8WDM8|F8WDM8_HUMAN,tr|E9PNK8|E9PNK8_HUMAN" 3 846.5146 0.84 110069 3673 2 846.514254 424.2646 Collagen alpha-1(XXIV) chain OS=Homo sapiens OX=9606 GN=COL24A1 PE=1 SV=2 10 1321.8 - 929737 - - - -0.3709 - 1.144 0.106 - 140.5 1 2 1 -0.0003 8 0 0 0 7.77E+07 9.20E+07 - - - 0.2296 0.9995 221125_WJC_METTL3_EV_vs_WT_F08.03674.03674.2 3.66E-06 26-Sep K.EEAGPGGAGGGGSR.V "sp|Q12872|SFSWA_HUMAN,tr|F5H1A5|F5H1A5_HUMAN" 2 1157.5061 1.26 110070 3674 2 1157.505715 579.7603 "Splicing factor, suppressor of white-apricot homolog OS=Homo sapiens OX=9606 GN=SFSWAP PE=1 SV=3" 4.53 1321.9 - 196177 - - - -0.3568 - 1.854 0.328 - 319.6 1 2 0 -0.0004 14 0 0 0 3.75E+06 2.97E+06 - - - 3.0127 0.9998 221125_WJC_METTL3_EV_vs_WT_F08.03679.03679.2 0.000636 20-Nov R.IAGQVAAANK[136.11]K[136.11].H "sp|P39019|RS19_HUMAN,tr|A0A075B6E2|A0A075B6E2_HUMAN" 2 1085.6528 1.18 110073 3679 2 1085.651167 543.8337 40S ribosomal protein S19 OS=Homo sapiens OX=9606 GN=RPS19 PE=1 SV=2 10 1322.4 - 4.11E+06 - - - -1.4977 - 2.34 0.457 - 391.5 1 2 0 -0.0016 11 0 0 0 7.89E+07 6.67E+07 - - - 4.7158 0.9992 221125_WJC_METTL3_EV_vs_WT_F08.03681.03681.2 0.579 12-Sep R.HDISDER.E "sp|P52756|RBM5_HUMAN,tr|C9J9P7|C9J9P7_HUMAN,tr|C9JR02|C9JR02_HUMAN,tr|C9JFQ5|C9JFQ5_HUMAN" 4 870.3832 1.11 110075 3681 2 870.381004 436.1989 RNA-binding protein 5 OS=Homo sapiens OX=9606 GN=RBM5 PE=1 SV=2 4.54 1322.6 - 902099 - - - -2.4759 - 1.845 0.367 - 285.2 1 2 0 -0.0022 7 0 0 0 2.04E+07 1.83E+07 - - - 3.6917 0.9693 221125_WJC_METTL3_EV_vs_WT_F08.03682.03682.2 0.00249 14-Oct P.R[166.11]GPPPPPR[166.11].L "sp|Q75N03|HAKAI_HUMAN,sp|P38159|RBMX_HUMAN,tr|H3BT71|H3BT71_HUMAN,tr|H0Y6E7|H0Y6E7_HUMAN" 4 892.5146 1.59 110076 3682 2 892.513068 447.2646 E3 ubiquitin-protein ligase Hakai OS=Homo sapiens OX=9606 GN=CBLL1 PE=1 SV=1 12 1322.7 - 502531 - - - -1.7277 - 1.856 0.365 - 207.6 1 1 0 -0.0015 8 0 0 0 1.49E+08 9.41E+07 - - - 3.6015 0.9531 221125_WJC_METTL3_EV_vs_WT_F08.03683.03683.2 0.223 18-Jul K.EVGK[136.11]DVSDEK[136.11].L "sp|O75390|CISY_HUMAN,tr|B4DJV2|B4DJV2_HUMAN,tr|A0A0C4DGI3|A0A0C4DGI3_HUMAN" 3 1120.5583 0.86 110077 3683 2 1120.557215 561.2864 "Citrate synthase, mitochondrial OS=Homo sapiens OX=9606 GN=CS PE=1 SV=2" 4.32 1322.8 - 282326 - - - -0.9531 - 1.307 0.207 - 133.1 1 2 1 -0.0011 10 0 0 0 7.29E+06 8.52E+06 - - - 1.3169 0.9239 221125_WJC_METTL3_EV_vs_WT_F08.03686.03686.2 0.152 12-Jul N.TTIPTK[136.11]K[136.11].S "sp|P38646|GRP75_HUMAN,tr|A0A7I2V2S7|A0A7I2V2S7_HUMAN,tr|A0A7I2V2G2|A0A7I2V2G2_HUMAN,tr|A0A7I2YQB2|A0A7I2YQB2_HUMAN,tr|D6RCD7|D6RCD7_HUMAN" 5 803.5088 0.42 110078 3686 2 803.507447 402.7617 "Stress-70 protein, mitochondrial OS=Homo sapiens OX=9606 GN=HSPA9 PE=1 SV=2" 10 1323.3 - 9.97E+06 - - - -1.6266 - 1.43 0.322 - 259.4 1 1 0 -0.0013 7 0 0 0 6.29E+07 1.50E+08 - - - 2.5522 0.8434 221125_WJC_METTL3_EV_vs_WT_F08.03689.03689.2 0.247 16-Jun K.VEPPK[136.11]EEQK[136.11].N sp|P34932|HSP74_HUMAN 1 1098.5892 0.26 110081 3689 2 1098.587159 550.3019 Heat shock 70 kDa protein 4 OS=Homo sapiens OX=9606 GN=HSPA4 PE=1 SV=4 4.79 1323.6 - 737483 - - - -1.8478 - 1.149 0.175 - 110.8 1 2 1 -0.002 9 0 0 0 3.35E+07 1.29E+08 - - - 0.7347 0.9407 221125_WJC_METTL3_EV_vs_WT_F08.03691.03691.2 0.308 22-Aug R.SSSSGQHGSGLG.E "sp|Q86YZ3|HORN_HUMAN,sp|Q86YZ3|HORN_HUMAN" 2 1059.4581 - 110083 3691 2 1059.456931 530.7363 Hornerin OS=Homo sapiens OX=9606 GN=HRNR PE=1 SV=2 6.46 1323.8 - 585444 - - - -1.1176 - 1.299 0.38 - 117.7 1 1 0 -0.0012 12 0 0 0 - - - - - 2.5356 0.9994 221125_WJC_METTL3_EV_vs_WT_F08.03698.03698.2 5.97E-06 14-Aug R.DC[160.03]QLNAHK[136.11].D "sp|Q13263|TIF1B_HUMAN,tr|M0R2I3|M0R2I3_HUMAN,tr|M0R3C0|M0R3C0_HUMAN" 3 992.4589 0.98 110088 3698 2 992.455891 497.2367 Transcription intermediary factor 1-beta OS=Homo sapiens OX=9606 GN=TRIM28 PE=1 SV=5 6.73 1324.6 - 1.51E+06 - - - -3.046 - 1.823 0.544 - 298.1 1 2 0 -0.003 8 0 0 0 2.01E+07 2.04E+07 - - - 4.8691 0.9978 221125_WJC_METTL3_EV_vs_WT_F08.03707.03707.2 0.0199 16-Aug R.QTQVNEATK.A "sp|Q8WWY3|PRP31_HUMAN,tr|E7EVX8|E7EVX8_HUMAN" 2 1017.5091 8.94 110095 3707 2 1017.506716 509.7618 U4\U6 small nuclear ribonucleoprotein Prp31 OS=Homo sapiens OX=9606 GN=PRPF31 PE=1 SV=2 6 1325.6 - 1.44E+07 - - - -2.3312 - 1.615 0.287 - 311.9 1 2 0 -0.0024 9 0 0 0 3.63E+08 4.06E+07 - - - 2.5468 0.9983 221125_WJC_METTL3_EV_vs_WT_F08.03709.03709.2 0.00106 18-Sep K.LPQTSDDEKK.D sp|Q9GZT3|SLIRP_HUMAN 1 1159.5721 1.17 110097 3709 2 1159.568525 580.7933 "SRA stem-loop-interacting RNA-binding protein, mitochondrial OS=Homo sapiens OX=9606 GN=SLIRP PE=1 SV=1" 4.56 1325.8 - 394248 - - - -3.0675 - 1.654 0.391 - 320.1 1 2 0 -0.0036 10 0 0 0 2.29E+07 1.95E+07 - - - 3.3324 0.9999 221125_WJC_METTL3_EV_vs_WT_F08.03715.03715.3 0.000141 15/36 K.LPQTSDDEK[136.11]K[136.11].D sp|Q9GZT3|SLIRP_HUMAN 1 1175.6005 1.32 110101 3715 3 1175.597062 392.8741 "SRA stem-loop-interacting RNA-binding protein, mitochondrial OS=Homo sapiens OX=9606 GN=SLIRP PE=1 SV=1" 4.56 1326.5 - 7.92E+06 - - - -2.9092 - 2.3 0.476 - 296.4 1 2 0 -0.0034 10 0 0 0 1.62E+08 1.22E+08 - - - 6.2784 0.9998 221125_WJC_METTL3_EV_vs_WT_F08.03716.03716.3 0.000273 13/36 K.LPQTSDDEKK.D sp|Q9GZT3|SLIRP_HUMAN 1 1159.5721 1.33 110102 3716 3 1159.568933 387.5313 "SRA stem-loop-interacting RNA-binding protein, mitochondrial OS=Homo sapiens OX=9606 GN=SLIRP PE=1 SV=1" 4.56 1326.6 - 8.60E+06 - - - -2.7157 - 2.351 0.425 - 200.7 1 2 0 -0.0032 10 0 0 0 1.61E+08 1.22E+08 - - - 5.774 0.9923 221125_WJC_METTL3_EV_vs_WT_F08.03720.03720.2 0.00462 16-Sep K.KSLGTQPPK.K "sp|Q14978|NOLC1_HUMAN,tr|A0A0A0MRM9|A0A0A0MRM9_HUMAN,tr|S4R349|S4R349_HUMAN" 3 954.5498 1.96 110106 3720 2 954.547517 478.2822 Nucleolar and coiled-body phosphoprotein 1 OS=Homo sapiens OX=9606 GN=NOLC1 PE=1 SV=2 10 1326.8 - 1.84E+06 - - - -2.4242 - 1.515 0.18 - 257.7 1 2 0 -0.0023 9 0 0 0 9.76E+07 4.99E+07 - - - 1.5716 0.9993 221125_WJC_METTL3_EV_vs_WT_F08.03721.03721.2 0.0012 18-Aug K.ATTAHDLSGK[136.11].L "sp|P55265|DSRAD_HUMAN,tr|A0A3B3IRQ9|A0A3B3IRQ9_HUMAN,tr|A0A3B3ISU1|A0A3B3ISU1_HUMAN,tr|A0A7P0Z4K3|A0A7P0Z4K3_HUMAN,tr|A0A3B3ISX1|A0A3B3ISX1_HUMAN" 5 1007.5127 1.16 110107 3721 2 1007.513047 504.7636 Double-stranded RNA-specific adenosine deaminase OS=Homo sapiens OX=9606 GN=ADAR PE=1 SV=4 6.79 1326.9 - 1.72E+06 - - - 0.3216 - 1.613 0.323 - 151.5 1 2 0 0.0003 10 0 0 0 2.88E+07 2.49E+07 - - - 2.7611 0.9995 221125_WJC_METTL3_EV_vs_WT_F08.03722.03722.2 0.00103 18-Oct K.LPQTSDDEK[136.11]K[136.11].D sp|Q9GZT3|SLIRP_HUMAN 1 1175.6005 1.16 110108 3722 2 1175.59775 588.8075 "SRA stem-loop-interacting RNA-binding protein, mitochondrial OS=Homo sapiens OX=9606 GN=SLIRP PE=1 SV=1" 4.56 1327 - 1.31E+06 - - - -2.3239 - 2.007 0.448 - 384.5 1 2 0 -0.0027 10 0 0 0 2.29E+07 1.98E+07 - - - 4.2936 0.9997 221125_WJC_METTL3_EV_vs_WT_F08.03726.03726.2 0.000388 14/16 R.R[166.11]ADDNATIR[166.11].V "sp|O75821|EIF3G_HUMAN,tr|K7ER90|K7ER90_HUMAN,tr|K7EL20|K7EL20_HUMAN,tr|K7ENA8|K7ENA8_HUMAN" 4 1050.5321 1.03 110111 3726 2 1050.529979 526.2733 Eukaryotic translation initiation factor 3 subunit G OS=Homo sapiens OX=9606 GN=EIF3G PE=1 SV=2 5.96 1327.4 - 3.38E+06 - - - -2.0294 - 2.584 0.402 - 438.9 1 2 0 -0.0021 9 0 0 0 4.49E+07 4.35E+07 - - - 4.756 0.9668 221125_WJC_METTL3_EV_vs_WT_F08.03732.03732.2 0.138 16-Sep L.PQTSDDEK[136.11]K[136.11].D sp|Q9GZT3|SLIRP_HUMAN 1 1062.5164 1.27 110117 3732 2 1062.515105 532.2655 "SRA stem-loop-interacting RNA-binding protein, mitochondrial OS=Homo sapiens OX=9606 GN=SLIRP PE=1 SV=1" 4.56 1327.9 - 445244 - - - -1.2357 - 1.823 0.326 - 310.8 1 1 0 -0.0013 9 0 0 0 2.35E+06 1.85E+06 - - - 3.1857 0.9974 221125_WJC_METTL3_EV_vs_WT_F08.03736.03736.2 0.0424 16-Sep R.RADDNATIR.V "sp|O75821|EIF3G_HUMAN,tr|K7ER90|K7ER90_HUMAN,tr|K7EL20|K7EL20_HUMAN,tr|K7ENA8|K7ENA8_HUMAN" 4 1030.5156 1.01 110119 3736 2 1030.51144 516.2651 Eukaryotic translation initiation factor 3 subunit G OS=Homo sapiens OX=9606 GN=EIF3G PE=1 SV=2 5.96 1328.5 - 5.65E+06 - - - -4.0087 - 2.09 0.338 - 156.3 1 2 0 -0.0041 9 0 0 0 4.49E+07 4.43E+07 - - - 3.6688 0.9425 221125_WJC_METTL3_EV_vs_WT_F08.03737.03737.2 0.155 12-Jul K.QHSLLKR.L "sp|P62841|RS15_HUMAN,tr|K7EJ78|K7EJ78_HUMAN,tr|K7EM56|K7EM56_HUMAN,tr|A0A0B4J2B4|A0A0B4J2B4_HUMAN,tr|S4R456|S4R456_HUMAN,tr|K7ELC2|K7ELC2_HUMAN,tr|K7EQJ5|K7EQJ5_HUMAN,tr|S4R417|S4R417_HUMAN" 8 880.5243 1.57 110120 3737 2 880.522163 441.2694 40S ribosomal protein S15 OS=Homo sapiens OX=9606 GN=RPS15 PE=1 SV=2 11 1328.6 - 1.53E+06 - - - -2.4099 - 1.334 0.025 - 305.6 1 2 0 -0.0021 7 0 0 0 1.65E+07 1.05E+07 - - - 0.1381 0.9932 221125_WJC_METTL3_EV_vs_WT_F08.03747.03747.3 0.0756 Nov-36 R.TR[166.11]NEMTAEEK[136.11].R sp|Q9Y5B9|SP16H_HUMAN 1 1225.5728 12.43 110128 3747 3 1225.571006 409.5315 FACT complex subunit SPT16 OS=Homo sapiens OX=9606 GN=SUPT16H PE=1 SV=1 4.78 1329.7 - 1.34E+06 - - - -1.4401 - 1.691 0.279 - 249.8 1 2 1 -0.0018 10 0 0 0 1.89E+08 1.52E+07 - - - 3.1842 1 221125_WJC_METTL3_EV_vs_WT_F08.03748.03748.2 2.72E-07 14/20 R.TGSQGQC[160.03]TQVR[166.11].V sp|P62857|RS28_HUMAN 1 1230.5651 0.86 110129 3748 2 1230.562829 616.2898 40S ribosomal protein S28 OS=Homo sapiens OX=9606 GN=RPS28 PE=1 SV=1 7.91 1329.8 - 1.01E+06 - - - -1.8081 - 2.827 0.528 - 778.5 1 2 0 -0.0022 11 0 0 0 3.01E+08 3.49E+08 - - - 5.7514 1 221125_WJC_METTL3_EV_vs_WT_F08.03749.03749.2 4.04E-06 14/20 R.TGSQGQC[160.03]TQVR.V sp|P62857|RS28_HUMAN 1 1220.5568 0.86 110130 3749 2 1220.557243 611.2857 40S ribosomal protein S28 OS=Homo sapiens OX=9606 GN=RPS28 PE=1 SV=1 7.91 1330 - 572120 - - - 0.3761 - 2.858 0.598 - 829 1 2 0 0.0005 11 0 0 0 3.01E+08 3.49E+08 - - - 6.2985 0.9998 221125_WJC_METTL3_EV_vs_WT_F08.03761.03761.2 5.89E-05 20-Dec K.GGGGSQINSTR.Y sp|P47974|TISD_HUMAN 1 1032.4948 1.41 110138 3761 2 1032.492887 517.2547 mRNA decay activator protein ZFP36L2 OS=Homo sapiens OX=9606 GN=ZFP36L2 PE=1 SV=3 9.75 1331.5 - 2.72E+06 - - - -1.8867 - 2.44 0.481 - 618.7 1 2 0 -0.0019 11 0 0 0 2.31E+07 1.64E+07 - - - 5.0061 0.9994 221125_WJC_METTL3_EV_vs_WT_F08.03772.03772.2 0.0107 20-Oct R.ASQNPGAAQPR.D sp|Q9Y5V3|MAGD1_HUMAN 1 1095.5421 1.5 110147 3772 2 1095.542115 548.7783 Melanoma-associated antigen D1 OS=Homo sapiens OX=9606 GN=MAGED1 PE=1 SV=3 9.79 1332.7 - 2.64E+06 - - - -0.0046 - 1.607 0.337 - 270.8 1 2 0 0 11 0 0 0 1.02E+08 6.79E+07 - - - 2.8134 0.9991 221125_WJC_METTL3_EV_vs_WT_F08.03773.03773.2 0.0729 18-Nov R.NSTGLGSQNK.F sp|Q8NDV7|TNR6A_HUMAN 1 1004.4887 2.67 110148 3773 2 1004.486129 503.2516 Trinucleotide repeat-containing gene 6A protein OS=Homo sapiens OX=9606 GN=TNRC6A PE=1 SV=2 8.75 1332.7 - 2.17E+06 - - - -2.5466 - 2.218 0.324 - 625.7 1 2 0 -0.0026 10 0 0 0 3.38E+07 1.27E+07 - - - 3.6568 0.9997 221125_WJC_METTL3_EV_vs_WT_F08.03774.03774.2 0.0124 15/18 K.K[136.11]GDSSAEELK[136.11].L sp|P26373|RL13_HUMAN 1 1078.5477 1.26 110149 3774 2 1078.546194 540.2811 60S ribosomal protein L13 OS=Homo sapiens OX=9606 GN=RPL13 PE=1 SV=4 4.68 1332.8 - 1.85E+06 - - - -1.4139 - 2.548 0.326 - 693.3 1 2 0 -0.0015 10 0 0 0 2.51E+08 1.99E+08 - - - 4.0591 0.9969 221125_WJC_METTL3_EV_vs_WT_F08.03777.03777.2 0.275 18-Jul R.SAVPPGADK[136.11]K[136.11].A "sp|P46783|RS10_HUMAN,tr|F6U211|F6U211_HUMAN,tr|A0A1W2PQS6|A0A1W2PQS6_HUMAN,tr|A0A2R8YFH6|A0A2R8YFH6_HUMAN,tr|A0A2R8Y7H1|A0A2R8Y7H1_HUMAN,tr|S4R435|S4R435_HUMAN" 6 984.5575 1.11 110152 3777 2 984.556353 493.286 40S ribosomal protein S10 OS=Homo sapiens OX=9606 GN=RPS10 PE=1 SV=1 8.31 1333.1 - 796485 - - - -1.1599 - 1.426 0.219 - 177.6 1 2 0 -0.0011 10 0 0 0 2.75E+07 2.48E+07 - - - 1.6487 0.999 221125_WJC_METTL3_EV_vs_WT_F08.03778.03778.2 0.0434 16-Jul K.K[136.11]IQNDAGVR[166.11].L "sp|Q96I24|FUBP3_HUMAN,sp|Q92945|FUBP2_HUMAN,sp|Q96AE4|FUBP1_HUMAN,tr|M0R0I5|M0R0I5_HUMAN,tr|E9PEB5|E9PEB5_HUMAN,tr|M0R0C6|M0R0C6_HUMAN,tr|A0A087WTP3|A0A087WTP3_HUMAN" 7 1017.5686 1.61 110153 3778 2 1017.567295 509.7916 Far upstream element-binding protein 3 OS=Homo sapiens OX=9606 GN=FUBP3 PE=1 SV=2 8.75 1333.3 - 596768 - - - -1.2943 - 1.712 0.282 - 188.2 1 2 0 -0.0013 9 0 0 0 4.83E+07 3.01E+07 - - - 2.6789 0.9994 221125_WJC_METTL3_EV_vs_WT_F08.03785.03785.2 0.21 16-Sep R.TRPSSDQLK.E sp|Q8N0X7|SPART_HUMAN 1 1030.5407 0.77 110158 3785 2 1030.54058 516.2776 Spartin OS=Homo sapiens OX=9606 GN=SPART PE=1 SV=1 8.41 1334.2 - 2.26E+06 - - - -0.1388 - 1.892 0.271 - 393.9 1 2 0 -0.0001 9 0 0 0 5.58E+07 7.26E+07 - - - 2.8873 0.9984 221125_WJC_METTL3_EV_vs_WT_F08.03786.03786.2 0.00444 16-Oct K.KIQNDAGVR.L "sp|Q96I24|FUBP3_HUMAN,sp|Q92945|FUBP2_HUMAN,sp|Q96AE4|FUBP1_HUMAN,tr|M0R0I5|M0R0I5_HUMAN,tr|E9PEB5|E9PEB5_HUMAN,tr|M0R0C6|M0R0C6_HUMAN,tr|A0A087WTP3|A0A087WTP3_HUMAN" 7 999.5461 1.6 110159 3786 2 999.547861 500.7803 Far upstream element-binding protein 3 OS=Homo sapiens OX=9606 GN=FUBP3 PE=1 SV=2 8.75 1334.2 - 1.69E+06 - - - 1.7198 - 2.014 0.2 - 403.8 1 2 0 0.0017 9 0 0 0 4.86E+07 3.03E+07 - - - 2.5432 0.9906 221125_WJC_METTL3_EV_vs_WT_F08.03787.03787.2 1.24 16-Aug K.HSLSGRPLK.V "sp|P52272|HNRPM_HUMAN,tr|M0R019|M0R019_HUMAN,tr|M0R0N3|M0R0N3_HUMAN,tr|A0A087X0X3|A0A087X0X3_HUMAN,tr|M0QYQ7|M0QYQ7_HUMAN,tr|M0R2T0|M0R2T0_HUMAN" 6 993.572 1.7 110160 3787 2 993.570355 497.7933 Heterogeneous nuclear ribonucleoprotein M OS=Homo sapiens OX=9606 GN=HNRNPM PE=1 SV=3 11 1334.4 - 1.24E+06 - - - -1.6184 - 1.427 0.146 - 112.1 2 2 0 -0.0016 9 0 0 0 3.73E+07 2.19E+07 - - - 1.0131 0.9995 221125_WJC_METTL3_EV_vs_WT_F08.03791.03791.2 0.104 26-Oct R.EAPGPAGGGGGGSR[166.11].W "sp|Q9BQ61|TRIR_HUMAN,tr|K7EN60|K7EN60_HUMAN,tr|K7ERU7|K7ERU7_HUMAN,tr|K7ELS0|K7ELS0_HUMAN" 4 1135.5246 0.66 110162 3791 2 1135.522625 568.7696 Telomerase RNA component interacting RNase OS=Homo sapiens OX=9606 GN=TRIR PE=1 SV=1 6.1 1334.8 - 2.02E+06 - - - -1.712 - 1.803 0.43 - 247 1 2 0 -0.0019 14 0 0 0 7.09E+07 1.08E+08 - - - 3.6956 0.9997 221125_WJC_METTL3_EV_vs_WT_F08.03797.03797.2 0.000943 26-Oct R.EAPGPAGGGGGGSR.W "sp|Q9BQ61|TRIR_HUMAN,tr|K7EN60|K7EN60_HUMAN,tr|K7ERU7|K7ERU7_HUMAN,tr|K7ELS0|K7ELS0_HUMAN" 4 1125.5163 0.66 110166 3797 2 1125.513931 563.7654 Telomerase RNA component interacting RNase OS=Homo sapiens OX=9606 GN=TRIR PE=1 SV=1 6.1 1335.5 - 1.48E+06 - - - -2.1039 - 1.837 0.545 - 256.4 1 2 0 -0.0024 14 0 0 0 7.09E+07 1.08E+08 - - - 4.5917 0.9967 221125_WJC_METTL3_EV_vs_WT_F08.03803.03803.2 0.0245 12-Sep K.HGWTQGK[136.11].G "sp|Q5T3I0|GPTC4_HUMAN,tr|E9PPY4|E9PPY4_HUMAN,tr|F2Z3C6|F2Z3C6_HUMAN,tr|F8W895|F8W895_HUMAN,tr|A0A0A0MRK1|A0A0A0MRK1_HUMAN,tr|E9PAV9|E9PAV9_HUMAN" 6 820.4071 1.69 110170 3803 2 820.4052 411.2108 G patch domain-containing protein 4 OS=Homo sapiens OX=9606 GN=GPATCH4 PE=1 SV=2 8.76 1336.2 - 1.97E+06 - - - -2.3598 - 1.437 0.277 - 260.4 1 2 0 -0.0019 7 0 0 0 7.01E+07 4.15E+07 - - - 2.2351 0.9792 221125_WJC_METTL3_EV_vs_WT_F08.03804.03804.2 0.166 16-Aug K.HSLSGR[166.11]PLK[136.11].V "sp|P52272|HNRPM_HUMAN,tr|M0R019|M0R019_HUMAN,tr|M0R0N3|M0R0N3_HUMAN,tr|A0A087X0X3|A0A087X0X3_HUMAN,tr|M0QYQ7|M0QYQ7_HUMAN,tr|M0R2T0|M0R2T0_HUMAN" 6 1011.5944 1.7 110171 3804 2 1011.592961 506.8045 Heterogeneous nuclear ribonucleoprotein M OS=Homo sapiens OX=9606 GN=HNRNPM PE=1 SV=3 11 1336.3 - 1.51E+06 - - - -1.4551 - 1.331 0.072 - 118.5 1 2 0 -0.0015 9 0 0 0 3.73E+07 2.19E+07 - - - 0.3995 0.9688 221125_WJC_METTL3_EV_vs_WT_F08.03805.03805.2 3.15 16-Aug R.NSPVGVNHR.L sp|Q99595|TI17A_HUMAN 1 978.4995 2.59 110172 3805 2 978.500054 490.257 Mitochondrial import inner membrane translocase subunit Tim17-A OS=Homo sapiens OX=9606 GN=TIMM17A PE=1 SV=1 9.76 1336.4 - 1.16E+06 - - - 0.5396 - 1.216 0.044 - 135.2 1 2 0 0.0005 9 0 0 0 1.63E+07 6.31E+06 - - - -0.0684 0.9993 221125_WJC_METTL3_EV_vs_WT_F08.03814.03814.2 0.0192 16-Sep K.TQGTNQIQK[136.11].N "sp|Q8IX01|SUGP2_HUMAN,tr|M0R2Z9|M0R2Z9_HUMAN,tr|M0R3F6|M0R3F6_HUMAN" 3 1024.5393 1.02 110179 3814 2 1024.54 513.2769 SURP and G-patch domain-containing protein 2 OS=Homo sapiens OX=9606 GN=SUGP2 PE=1 SV=2 8.41 1337.4 - 3.53E+06 - - - 0.7096 - 1.628 0.319 - 243.3 1 2 0 0.0007 9 0 0 0 4.65E+07 4.54E+07 - - - 2.8068 0.9892 221125_WJC_METTL3_EV_vs_WT_F08.03815.03815.3 0.0409 Oct-36 K.QVAQASHSYR[166.11].V sp|O43819|SCO2_HUMAN 1 1155.566 0.93 110180 3815 3 1155.564051 386.196 "Protein SCO2 homolog, mitochondrial OS=Homo sapiens OX=9606 GN=SCO2 PE=1 SV=3" 8.75 1337.5 - 3.64E+06 - - - -1.7212 - 1.846 0.15 - 158.7 1 2 0 -0.002 10 0 0 0 1.14E+08 1.23E+08 - - - 2.0021 0.9981 221125_WJC_METTL3_EV_vs_WT_F08.03816.03816.3 0.175 Nov-36 K.QVAQASHSYR.V sp|O43819|SCO2_HUMAN 1 1145.5578 0.93 110181 3816 3 1145.556103 382.8599 "Protein SCO2 homolog, mitochondrial OS=Homo sapiens OX=9606 GN=SCO2 PE=1 SV=3" 8.75 1337.5 - 3.15E+06 - - - -1.4552 - 2.134 0.205 - 224.3 1 2 0 -0.0017 10 0 0 0 1.14E+08 1.23E+08 - - - 3.0388 0.9662 221125_WJC_METTL3_EV_vs_WT_F08.03817.03817.3 0.143 Oct-36 R.EALQEK[136.11]EEQK[136.11].T "sp|Q13435|SF3B2_HUMAN,tr|E9PPJ0|E9PPJ0_HUMAN" 2 1246.6376 2.5 110182 3817 3 1246.635794 416.5531 Splicing factor 3B subunit 2 OS=Homo sapiens OX=9606 GN=SF3B2 PE=1 SV=2 4.49 1337.6 - 1.38E+06 - - - -1.4455 - 1.959 0.145 - 124.9 1 2 1 -0.0018 10 0 0 0 4.15E+07 1.66E+07 - - - 2.1199 0.9991 221125_WJC_METTL3_EV_vs_WT_F08.03820.03820.2 0.0358 14-Jun R.DSYSSSSR.G "sp|Q96E39|RMXL1_HUMAN,sp|P38159|RBMX_HUMAN,tr|H3BUY5|H3BUY5_HUMAN" 3 887.3621 2.59 110185 3820 2 887.360537 444.6883 "RNA binding motif protein, X-linked-like-1 OS=Homo sapiens OX=9606 GN=RBMXL1 PE=1 SV=1" 5.84 1337.9 - 751869 - - - -1.7501 - 1.18 0.47 - 117.7 1 2 0 -0.0016 8 0 0 0 8.45E+06 3.26E+06 - - - 3.0111 0.9999 221125_WJC_METTL3_EV_vs_WT_F08.03821.03821.2 9.50E-05 18-Oct K.QVAQASHSYR.V sp|O43819|SCO2_HUMAN 1 1145.5578 0.98 110186 3821 2 1145.558277 573.7862 "Protein SCO2 homolog, mitochondrial OS=Homo sapiens OX=9606 GN=SCO2 PE=1 SV=3" 8.75 1338 - 364538 - - - 0.4426 - 1.904 0.539 - 355.5 1 2 0 0.0005 10 0 0 0 1.72E+07 1.75E+07 - - - 4.8194 0.9978 221125_WJC_METTL3_EV_vs_WT_F08.03823.03823.2 0.00194 18-Aug R.EALQEK[136.11]EEQK[136.11].T "sp|Q13435|SF3B2_HUMAN,tr|E9PPJ0|E9PPJ0_HUMAN" 2 1246.6376 1.17 110188 3823 2 1246.637185 624.3261 Splicing factor 3B subunit 2 OS=Homo sapiens OX=9606 GN=SF3B2 PE=1 SV=2 4.49 1338.3 - 254491 - - - -0.3297 - 1.758 0.472 - 257.1 1 2 1 -0.0004 10 0 0 0 3.14E+06 2.69E+06 - - - 4.1019 0.9996 221125_WJC_METTL3_EV_vs_WT_F08.03827.03827.2 0.00157 14-Sep K.EEFEHQQK[136.11].E "sp|P11142|HSP7C_HUMAN,tr|E9PNE6|E9PNE6_HUMAN,tr|A8K7Q2|A8K7Q2_HUMAN,tr|E9PKE3|E9PKE3_HUMAN,tr|E9PM13|E9PM13_HUMAN,tr|E9PS65|E9PS65_HUMAN" 6 1081.492 0.18 110190 3827 2 1081.490253 541.7533 Heat shock cognate 71 kDa protein OS=Homo sapiens OX=9606 GN=HSPA8 PE=1 SV=1 4.75 1338.9 - 1.37E+07 - - - -1.6043 - 1.63 0.44 - 329.5 1 2 0 -0.0017 8 0 0 0 2.51E+07 1.39E+08 - - - 3.7638 0.9999 221125_WJC_METTL3_EV_vs_WT_F08.03830.03830.2 5.12E-05 18-Dec K.QVAQASHSYR[166.11].V sp|O43819|SCO2_HUMAN 1 1155.566 0.98 110193 3830 2 1155.566417 578.7903 "Protein SCO2 homolog, mitochondrial OS=Homo sapiens OX=9606 GN=SCO2 PE=1 SV=3" 8.75 1339.1 - 1.39E+06 - - - 0.3262 - 2.337 0.487 - 724.7 1 2 0 0.0004 10 0 0 0 1.72E+07 1.75E+07 - - - 5.0073 0.9996 221125_WJC_METTL3_EV_vs_WT_F08.03832.03832.2 0.00254 16-Jul R.AAVAGEDGR.M "sp|P0DMR1|HNRC4_HUMAN,sp|P07910|HNRPC_HUMAN,sp|O60812|HNRC1_HUMAN,sp|B2RXH8|HNRC2_HUMAN,sp|B7ZW38|HNRC3_HUMAN,tr|G3V251|G3V251_HUMAN,tr|B4DY08|B4DY08_HUMAN,tr|G3V575|G3V575_HUMAN,tr|B4DSU6|B4DSU6_HUMAN,tr|G3V3K6|G3V3K6_HUMAN,tr|B2R5W2|B2R5W2_HUMAN,tr|G3V4C1|G3V4C1_HUMAN,tr|A0A0G2JPF8|A0A0G2JPF8_HUMAN,tr|A0A0G2JNQ3|A0A0G2JNQ3_HUMAN,tr|G3V576|G3V576_HUMAN,tr|G3V5X6|G3V5X6_HUMAN,tr|G3V4W0|G3V4W0_HUMAN,tr|G3V555|G3V555_HUMAN,tr|G3V2Q1|G3V2Q1_HUMAN" 19 844.4039 1.96 110195 3832 2 844.402822 423.2092 Heterogeneous nuclear ribonucleoprotein C-like 4 OS=Homo sapiens OX=9606 GN=HNRNPCL4 PE=3 SV=1 4.37 1339.3 - 668147 - - - -1.2707 - 1.744 0.407 - 171.6 1 2 0 -0.0011 9 0 0 0 6.96E+06 3.55E+06 - - - 3.6558 0.9797 221125_WJC_METTL3_EV_vs_WT_F08.03833.03833.2 0.0219 12-Jun R.RSDPNFK.N sp|Q15388|TOM20_HUMAN 1 862.4297 0.98 110196 3833 2 862.427869 432.2221 Mitochondrial import receptor subunit TOM20 homolog OS=Homo sapiens OX=9606 GN=TOMM20 PE=1 SV=1 8.75 1339.4 - 501587 - - - -2.1416 - 1.401 0.083 - 173.8 1 2 0 -0.0018 7 0 0 0 2.18E+08 2.21E+08 - - - 0.7219 0.9994 221125_WJC_METTL3_EV_vs_WT_F08.03840.03840.2 0.0171 14-Jul K.EEFEHQQK.E "sp|P11142|HSP7C_HUMAN,tr|E9PNE6|E9PNE6_HUMAN,tr|A8K7Q2|A8K7Q2_HUMAN,tr|E9PKE3|E9PKE3_HUMAN,tr|E9PM13|E9PM13_HUMAN,tr|E9PS65|E9PS65_HUMAN" 6 1073.4778 0.18 110201 3840 2 1073.476073 537.7462 Heat shock cognate 71 kDa protein OS=Homo sapiens OX=9606 GN=HSPA8 PE=1 SV=1 4.75 1340.2 - 3.07E+06 - - - -1.5976 - 1.371 0.459 - 181.1 1 2 0 -0.0017 8 0 0 0 2.51E+07 1.39E+08 - - - 3.3823 0.9909 221125_WJC_METTL3_EV_vs_WT_F08.03841.03841.2 0.00898 14-Sep R.DDKDTIEK.L "sp|P63000|RAC1_HUMAN,sp|P15153|RAC2_HUMAN,tr|B1AH77|B1AH77_HUMAN,tr|B1AH78|B1AH78_HUMAN,tr|B1AH80|B1AH80_HUMAN" 5 962.4557 1.24 110202 3841 2 962.45408 482.2351 Ras-related C3 botulinum toxin substrate 1 OS=Homo sapiens OX=9606 GN=RAC1 PE=1 SV=1 4.23 1340.2 - 2.35E+06 - - - -1.6375 - 1.783 0.308 - 274.5 1 2 1 -0.0016 8 0 0 0 3.62E+07 2.91E+07 - - - 3.0595 0.9995 221125_WJC_METTL3_EV_vs_WT_F08.03843.03843.2 0.000657 20-Sep K.ETPSSANGPSR[166.11].E "sp|O95817|BAG3_HUMAN,tr|C9JFK9|C9JFK9_HUMAN" 2 1111.5133 0.35 110204 3843 2 1111.51181 556.7639 BAG family molecular chaperone regulator 3 OS=Homo sapiens OX=9606 GN=BAG3 PE=1 SV=3 6.1 1340.4 - 1.03E+06 - - - -1.372 - 1.753 0.378 - 379.3 1 2 0 -0.0015 11 0 0 0 6.86E+06 1.95E+07 - - - 3.351 0.9926 221125_WJC_METTL3_EV_vs_WT_F08.03844.03844.2 0.0355 12-Jun R.R[166.11]SDPNFK[136.11].N sp|Q15388|TOM20_HUMAN 1 880.4522 1.69 110205 3844 2 880.45188 441.2334 Mitochondrial import receptor subunit TOM20 homolog OS=Homo sapiens OX=9606 GN=TOMM20 PE=1 SV=1 8.75 1340.5 - 985322 - - - -0.3475 - 1.337 0.117 - 207.8 1 2 0 -0.0003 7 0 0 0 2.08E+08 1.23E+08 - - - 0.8253 0.9773 221125_WJC_METTL3_EV_vs_WT_F08.03845.03845.2 0.00543 22-Oct W.ADGGQHSSIHPA.- "sp|O00746|NDKM_HUMAN,tr|Q4TT34|Q4TT34_HUMAN,tr|A0A087WVT9|A0A087WVT9_HUMAN" 3 1175.5319 - 110206 3845 2 1175.531151 588.7733 "Nucleoside diphosphate kinase, mitochondrial OS=Homo sapiens OX=9606 GN=NME4 PE=1 SV=1" 5.97 1340.6 - 582990 - - - -0.6788 - 1.659 0.405 - 186.2 1 1 0 -0.0008 12 0 0 0 - - - - - 3.364 0.9187 221125_WJC_METTL3_EV_vs_WT_F08.03846.03846.2 0.000578 18-Oct K.TTEALK[136.11]SEEK[136.11].A "sp|Q5SW79|CE170_HUMAN,tr|H0Y2V6|H0Y2V6_HUMAN" 2 1150.6052 3.58 110207 3846 2 1150.59874 576.3099 Centrosomal protein of 170 kDa OS=Homo sapiens OX=9606 GN=CEP170 PE=1 SV=1 4.78 1340.7 - 452018 - - - -5.6431 - 1.985 0.378 - 337.2 1 2 1 -0.0065 10 0 0 0 1.19E+07 3.33E+06 - - - 3.7446 0.9944 221125_WJC_METTL3_EV_vs_WT_F08.03847.03847.2 0.00621 18-Sep R.EALQEKEEQK.T "sp|Q13435|SF3B2_HUMAN,tr|E9PPJ0|E9PPJ0_HUMAN" 2 1230.6092 1.17 110208 3847 2 1230.609927 616.3119 Splicing factor 3B subunit 2 OS=Homo sapiens OX=9606 GN=SF3B2 PE=1 SV=2 4.49 1340.8 - 436125 - - - 0.594 - 1.672 0.361 - 334.8 1 2 1 0.0007 10 0 0 0 3.14E+06 2.69E+06 - - - 3.1419 0.9856 221125_WJC_METTL3_EV_vs_WT_F08.03854.03854.2 0.0446 16-Nov E.VAGTVTGQK[136.11].R "sp|Q86U44|MTA70_HUMAN,tr|F5H6D8|F5H6D8_HUMAN,tr|H0YFV6|H0YFV6_HUMAN,tr|B4DTN4|B4DTN4_HUMAN" 4 867.4905 0.02 110213 3854 2 867.489678 434.7525 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 8.72 1341.5 - 4.88E+06 - - - -0.9833 - 2.18 0.373 - 316.7 1 1 0 -0.0009 9 0 0 0 1.43E+06 5.73E+07 - - - 4.0503 0.9922 221125_WJC_METTL3_EV_vs_WT_F08.03866.03866.2 0.116 12-Jul K.EQDYR[166.11]PK[136.11].A "sp|Q9NRA8|4ET_HUMAN,tr|B1AKL4|B1AKL4_HUMAN" 2 952.4733 0.95 110223 3866 2 952.474651 477.2439 Eukaryotic translation initiation factor 4E transporter OS=Homo sapiens OX=9606 GN=EIF4ENIF1 PE=1 SV=2 6.17 1342.9 - 1.23E+06 - - - 1.4027 - 1.189 0.209 - 263.1 1 2 0 0.0013 7 0 0 0 7.02E+07 7.42E+07 - - - 1.1328 0.9985 221125_WJC_METTL3_EV_vs_WT_F08.03867.03867.2 0.0235 12-Jul K.HPELADK.N "sp|Q9NQ39|RS10L_HUMAN,sp|P46783|RS10_HUMAN,tr|A0A2R8Y6L3|A0A2R8Y6L3_HUMAN,tr|F6U211|F6U211_HUMAN,tr|A0A1W2PQS6|A0A1W2PQS6_HUMAN,tr|A0A2R8YFH6|A0A2R8YFH6_HUMAN,tr|A0A2R8Y7H1|A0A2R8Y7H1_HUMAN,tr|S4R435|S4R435_HUMAN" 8 808.4079 1.49 110224 3867 2 808.406777 405.2112 Putative 40S ribosomal protein S10-like OS=Homo sapiens OX=9606 GN=RPS10P5 PE=5 SV=1 5.32 1342.9 - 3.81E+06 - - - -1.4114 - 1.501 0.278 - 117.9 1 2 0 -0.0011 7 0 0 0 9.32E+07 6.24E+07 - - - 2.3808 1 221125_WJC_METTL3_EV_vs_WT_F08.03868.03868.3 1.46E-05 18/44 R.VLSGASQKPASR.V "sp|P08559|ODPA_HUMAN,tr|Q5JPT9|Q5JPT9_HUMAN,tr|Q5JPU0|Q5JPU0_HUMAN" 3 1199.6622 1.58 110225 3868 3 1199.660781 400.8947 "Pyruvate dehydrogenase E1 component subunit alpha, somatic form, mitochondrial OS=Homo sapiens OX=9606 GN=PDHA1 PE=1 SV=3" 11 1343 - 1.38E+06 - - - -1.212 - 2.736 0.463 - 299.9 1 2 0 -0.0015 12 0 0 0 1.18E+07 7.46E+06 - - - 6.4914 0.9992 221125_WJC_METTL3_EV_vs_WT_F08.03871.03871.2 0.000701 14-Aug R.HSC[160.03]DALNR.W "sp|Q6P996|PDXD1_HUMAN,tr|Q86XE2|Q86XE2_HUMAN,tr|H3BND4|H3BND4_HUMAN,tr|Q6XYB5|Q6XYB5_HUMAN" 4 971.4243 0.75 110228 3871 2 971.421424 486.7194 Pyridoxal-dependent decarboxylase domain-containing protein 1 OS=Homo sapiens OX=9606 GN=PDXDC1 PE=1 SV=2 6.74 1343.2 - 1.29E+06 - - - -2.974 - 1.683 0.494 - 176.1 1 2 0 -0.0029 8 0 0 0 1.02E+07 1.36E+07 - - - 4.2588 0.9953 221125_WJC_METTL3_EV_vs_WT_F08.03872.03872.2 0.00331 16-Oct R.ASNYQSTTR[166.11].V sp|Q9Y6A4|CFA20_HUMAN 1 1036.4813 1.75 110229 3872 2 1036.476225 519.2479 Cilia- and flagella-associated protein 20 OS=Homo sapiens OX=9606 GN=CFAP20 PE=1 SV=1 8.79 1343.3 - 945908 - - - -4.9031 - 1.897 0.385 - 398.1 1 2 0 -0.0051 9 0 0 0 1.51E+07 8.66E+06 - - - 3.7354 0.9152 221125_WJC_METTL3_EV_vs_WT_F08.03874.03874.2 0.0161 12-Jul E.GQHYPER.H sp|Q15424|SAFB1_HUMAN 1 885.4093 0.38 110231 3874 2 885.408084 443.7119 Scaffold attachment factor B1 OS=Homo sapiens OX=9606 GN=SAFB PE=1 SV=4 6.75 1343.5 - 668136 - - - -1.3892 - 1.37 0.309 - 267.5 1 1 0 -0.0012 7 0 0 0 8.44E+06 2.25E+07 - - - 2.3204 0.9998 221125_WJC_METTL3_EV_vs_WT_F08.03877.03877.2 0.0258 22-Sep R.VLSGASQKPASR.V "sp|P08559|ODPA_HUMAN,tr|Q5JPT9|Q5JPT9_HUMAN,tr|Q5JPU0|Q5JPU0_HUMAN" 3 1199.6622 2.54 110234 3877 2 1199.662733 600.8384 "Pyruvate dehydrogenase E1 component subunit alpha, somatic form, mitochondrial OS=Homo sapiens OX=9606 GN=PDHA1 PE=1 SV=3" 11 1343.9 - 137609 - - - 0.4151 - 1.726 0.466 - 294.4 1 2 0 0.0005 12 0 0 0 8.79E+05 3.47E+05 - - - 3.9188 0.9994 221125_WJC_METTL3_EV_vs_WT_F08.03882.03882.2 0.000228 12-Oct K.HPELADK[136.11].N "sp|Q9NQ39|RS10L_HUMAN,sp|P46783|RS10_HUMAN,tr|A0A2R8Y6L3|A0A2R8Y6L3_HUMAN,tr|F6U211|F6U211_HUMAN,tr|A0A1W2PQS6|A0A1W2PQS6_HUMAN,tr|A0A2R8YFH6|A0A2R8YFH6_HUMAN,tr|A0A2R8Y7H1|A0A2R8Y7H1_HUMAN,tr|S4R435|S4R435_HUMAN" 8 816.4221 1.51 110237 3882 2 816.421367 409.2183 Putative 40S ribosomal protein S10-like OS=Homo sapiens OX=9606 GN=RPS10P5 PE=5 SV=1 5.32 1344.4 - 5.62E+06 - - - -0.9199 - 1.93 0.251 - 314.6 1 2 0 -0.0008 7 0 0 0 9.44E+07 6.26E+07 - - - 2.978 0.9974 221125_WJC_METTL3_EV_vs_WT_F08.03884.03884.3 0.0093 Nov-36 K.QLDQGNK[136.11]DVR[166.11].H sp|Q8N0X7|SPART_HUMAN 1 1189.617 1.05 110239 3884 3 1189.616039 397.5463 Spartin OS=Homo sapiens OX=9606 GN=SPART PE=1 SV=1 5.96 1344.6 - 1.84E+06 - - - -0.8238 - 1.727 0.323 - 160.4 1 2 1 -0.001 10 0 0 0 8.60E+07 8.20E+07 - - - 3.7365 0.9995 221125_WJC_METTL3_EV_vs_WT_F08.03885.03885.2 0.00153 16-Aug K.VHQLETQNR[166.11].A sp|Q16352|AINX_HUMAN 1 1133.5817 2.04 110240 3885 2 1133.580242 567.7981 Alpha-internexin OS=Homo sapiens OX=9606 GN=INA PE=1 SV=2 6.72 1344.6 - 1.81E+06 - - - -1.2774 - 1.604 0.397 - 270.7 1 2 0 -0.0014 9 0 0 0 2.66E+07 1.30E+07 - - - 3.3398 0.9987 221125_WJC_METTL3_EV_vs_WT_F08.03887.03887.2 0.522 18-Sep R.GGSDGYGSGR[166.11].G "sp|P22626|ROA2_HUMAN,tr|A0A024RA28|A0A024RA28_HUMAN,tr|A0A7I2V4N1|A0A7I2V4N1_HUMAN,tr|A0A7I2V4S4|A0A7I2V4S4_HUMAN,tr|A0A7I2V323|A0A7I2V323_HUMAN,tr|A0A7I2V3P1|A0A7I2V3P1_HUMAN,tr|A0A7I2V3P7|A0A7I2V3P7_HUMAN" 7 921.3816 1.14 110242 3887 2 921.37931 461.6981 Heterogeneous nuclear ribonucleoproteins A2\B1 OS=Homo sapiens OX=9606 GN=HNRNPA2B1 PE=1 SV=2 5.84 1344.8 - 753967 - - - -2.4778 - 1.896 0.323 - 337.8 1 2 0 -0.0023 10 0 0 0 3.02E+07 2.65E+07 - - - 3.2117 0.9997 221125_WJC_METTL3_EV_vs_WT_F08.03892.03892.2 0.00715 18-Dec R.SVSQQASQER[166.11].N "sp|Q9Y2H2|SAC2_HUMAN,tr|A0A3B3IRJ9|A0A3B3IRJ9_HUMAN,tr|A0A3B3ITL0|A0A3B3ITL0_HUMAN" 3 1128.5399 0.42 110245 3892 2 1128.537732 565.2772 Phosphatidylinositide phosphatase SAC2 OS=Homo sapiens OX=9606 GN=INPP5F PE=1 SV=3 5.72 1345.4 - 2.75E+06 - - - -1.9078 - 2.265 0.422 - 517.3 1 2 0 -0.0022 10 0 0 0 1.69E+07 4.05E+07 - - - 4.4393 0.9964 221125_WJC_METTL3_EV_vs_WT_F08.03894.03894.2 0.00175 18-Oct K.SHAEIAEQAK[136.11].H "sp|Q6ZRS2|SRCAP_HUMAN,tr|A0A0C4DFX4|A0A0C4DFX4_HUMAN" 2 1090.5498 0.26 110247 3894 2 1090.548997 546.2822 Helicase SRCAP OS=Homo sapiens OX=9606 GN=SRCAP PE=1 SV=3 5.38 1345.6 - 667478 - - - -0.7703 - 1.674 0.127 - 249 1 2 0 -0.0008 10 0 0 0 2.37E+06 8.98E+06 - - - 1.4169 0.9934 221125_WJC_METTL3_EV_vs_WT_F08.03895.03895.2 6.39E-05 18-Dec K.QLDQGNK[136.11]DVR[166.11].H sp|Q8N0X7|SPART_HUMAN 1 1189.617 1.02 110248 3895 2 1189.620308 595.8158 Spartin OS=Homo sapiens OX=9606 GN=SPART PE=1 SV=1 5.96 1345.8 - 459112 - - - 2.7648 - 2.082 0.459 - 419.8 1 2 1 0.0033 10 0 0 0 9.46E+06 9.27E+06 - - - 4.4771 0.9997 221125_WJC_METTL3_EV_vs_WT_F08.03896.03896.2 0.00179 18-Nov R.R[166.11]LSQPESAEK[136.11].H "sp|Q9UKV3|ACINU_HUMAN,tr|S4R3H4|S4R3H4_HUMAN,tr|E7EQT4|E7EQT4_HUMAN" 3 1161.6109 1.3 110249 3896 2 1161.609774 581.8127 Apoptotic chromatin condensation inducer in the nucleus OS=Homo sapiens OX=9606 GN=ACIN1 PE=1 SV=2 6.14 1345.9 - 238371 - - - -0.9444 - 2.164 0.363 - 385.8 1 2 0 -0.0011 10 0 0 0 1.60E+07 1.23E+07 - - - 3.8765 0.9946 221125_WJC_METTL3_EV_vs_WT_F08.03899.03899.2 0.151 12-Jun K.EQDYRPK.A "sp|Q9NRA8|4ET_HUMAN,tr|B1AKL4|B1AKL4_HUMAN" 2 934.4508 0.88 110251 3899 2 934.450724 468.2327 Eukaryotic translation initiation factor 4E transporter OS=Homo sapiens OX=9606 GN=EIF4ENIF1 PE=1 SV=2 6.17 1346.2 - 5.48E+06 - - - -0.1295 - 1.161 0.207 - 241.4 1 2 0 -0.0001 7 0 0 0 7.13E+07 8.09E+07 - - - 1.0429 0.9983 221125_WJC_METTL3_EV_vs_WT_F08.03901.03901.3 0.00367 Oct-36 K.QLDQGNKDVR.H sp|Q8N0X7|SPART_HUMAN 1 1171.5945 1.05 110252 3901 3 1171.593688 391.5388 Spartin OS=Homo sapiens OX=9606 GN=SPART PE=1 SV=1 5.96 1346.4 - 7.97E+06 - - - -0.7349 - 1.779 0.342 - 138.5 1 2 1 -0.0009 10 0 0 0 8.60E+07 8.20E+07 - - - 4.035 0.9973 221125_WJC_METTL3_EV_vs_WT_F08.03906.03906.2 0.000124 18-Nov K.QLDQGNKDVR.H sp|Q8N0X7|SPART_HUMAN 1 1171.5945 1.02 110257 3906 2 1171.594545 586.8046 Spartin OS=Homo sapiens OX=9606 GN=SPART PE=1 SV=1 5.96 1346.8 - 844647 - - - -0.0034 - 2.316 0.331 - 352 1 2 1 0 10 0 0 0 9.46E+06 9.27E+06 - - - 3.83 0.9978 221125_WJC_METTL3_EV_vs_WT_F08.03912.03912.2 0.391 12-Aug R.NQEIPHK[136.11].G sp|O00743|PPP6_HUMAN 1 872.4596 1.28 110262 3912 2 872.458994 437.2371 Serine\threonine-protein phosphatase 6 catalytic subunit OS=Homo sapiens OX=9606 GN=PPP6C PE=1 SV=1 6.75 1347.5 - 1.22E+06 - - - -0.6556 - 1.43 0.216 - 357.3 1 2 0 -0.0006 7 0 0 0 2.82E+07 2.20E+07 - - - 1.7695 0.9998 221125_WJC_METTL3_EV_vs_WT_F08.03915.03915.2 0.000253 18-Aug R.ILHENTQTDK.A "sp|Q6UB35|C1TM_HUMAN,tr|A0A087WVM4|A0A087WVM4_HUMAN,tr|B7ZM99|B7ZM99_HUMAN" 3 1197.599 1.22 110264 3915 2 1197.599651 599.8068 "Monofunctional C1-tetrahydrofolate synthase, mitochondrial OS=Homo sapiens OX=9606 GN=MTHFD1L PE=1 SV=1" 5.32 1347.9 - 258492 - - - 0.572 - 1.598 0.5 - 211.2 1 2 0 0.0007 10 0 0 0 3.29E+06 2.69E+06 - - - 4.0422 0.9992 221125_WJC_METTL3_EV_vs_WT_F08.03921.03921.2 0.0255 18-Nov R.RLSQPESAEK.H "sp|Q9UKV3|ACINU_HUMAN,tr|S4R3H4|S4R3H4_HUMAN,tr|E7EQT4|E7EQT4_HUMAN" 3 1143.5884 1.29 110268 3921 2 1143.58738 572.8015 Apoptotic chromatin condensation inducer in the nucleus OS=Homo sapiens OX=9606 GN=ACIN1 PE=1 SV=2 6.14 1348.5 - 1.23E+06 - - - -0.8928 - 2.108 0.213 - 403.8 1 2 0 -0.001 10 0 0 0 1.59E+07 1.23E+07 - - - 2.6955 0.993 221125_WJC_METTL3_EV_vs_WT_F08.03924.03924.2 4.19E-05 18-Oct R.ERGGPEEGVR.G sp|Q9HCD5|NCOA5_HUMAN 1 1084.5261 0.43 110271 3924 2 1084.523217 543.2703 Nuclear receptor coactivator 5 OS=Homo sapiens OX=9606 GN=NCOA5 PE=1 SV=2 4.79 1348.8 - 512308 - - - -2.6906 - 1.946 0.455 - 136.9 1 2 1 -0.0029 10 0 0 0 1.73E+07 4.04E+07 - - - 4.2591 0.9852 221125_WJC_METTL3_EV_vs_WT_F08.03926.03926.2 0.00276 18-Aug R.ILHENTQTDK[136.11].A "sp|Q6UB35|C1TM_HUMAN,tr|A0A087WVM4|A0A087WVM4_HUMAN,tr|B7ZM99|B7ZM99_HUMAN" 3 1205.6132 1.22 110273 3926 2 1205.619373 603.8139 "Monofunctional C1-tetrahydrofolate synthase, mitochondrial OS=Homo sapiens OX=9606 GN=MTHFD1L PE=1 SV=1" 5.32 1349.1 - 339155 - - - 5.1484 - 1.657 0.308 - 248.8 1 2 0 0.0062 10 0 0 0 3.29E+06 2.69E+06 - - - 2.7236 0.896 221125_WJC_METTL3_EV_vs_WT_F08.03930.03930.2 2.11 12-Apr K.KDMMDIK.Y sp|Q96RL7|VP13A_HUMAN 1 879.4194 1.54 110275 3930 2 879.42097 440.717 Vacuolar protein sorting-associated protein 13A OS=Homo sapiens OX=9606 GN=VPS13A PE=1 SV=2 5.96 1349.6 - 5.28E+06 - - - 1.7739 - 0.834 0.141 - 89.8 1 2 0 0.0016 7 0 0 0 2.18E+09 1.41E+09 - - - -0.4932 0.9973 221125_WJC_METTL3_EV_vs_WT_F08.03937.03937.2 0.0852 18-Aug K.TTPTQPSEQK.A sp|O95104|SCAF4_HUMAN 1 1115.5459 0.79 110280 3937 2 1115.547757 558.7802 SR-related and CTD-associated factor 4 OS=Homo sapiens OX=9606 GN=SCAF4 PE=1 SV=3 5.66 1350.4 - 467264 - - - 1.6933 - 1.344 0.3 - 166 1 2 0 0.0019 10 0 0 0 1.26E+07 1.61E+07 - - - 2.0815 0.9997 221125_WJC_METTL3_EV_vs_WT_F08.03940.03940.2 0.00379 16-Oct K.VEQHVVDGK[136.11].E sp|Q9Y3I0|RTCB_HUMAN 1 1017.5335 1.55 110283 3940 2 1017.53357 509.774 RNA-splicing ligase RtcB homolog OS=Homo sapiens OX=9606 GN=RTCB PE=1 SV=1 5.32 1350.7 - 294609 - - - 0.1091 - 2.054 0.321 - 425.4 1 2 0 0.0001 9 0 0 0 1.18E+07 7.60E+06 - - - 3.4943 0.9984 221125_WJC_METTL3_EV_vs_WT_F08.03942.03942.2 0.000289 18-Jul R.LDGQTPHDER.Q sp|O60264|SMCA5_HUMAN 1 1166.5316 0.01 110285 3942 2 1166.528184 584.2731 SWI\SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A member 5 OS=Homo sapiens OX=9606 GN=SMARCA5 PE=1 SV=1 4.54 1350.9 - 116331 - - - -2.9412 - 1.635 0.395 - 104.5 1 2 0 -0.0034 10 0 0 0 2.85E+06 2.01E+08 - - - 3.3297 0.9997 221125_WJC_METTL3_EV_vs_WT_F08.03947.03947.3 0.00634 Oct-36 R.AAQMHSGYQR[166.11].R sp|Q96PK6|RBM14_HUMAN 1 1157.5275 1.75 110288 3947 3 1157.525856 386.8498 RNA-binding protein 14 OS=Homo sapiens OX=9606 GN=RBM14 PE=1 SV=2 8.8 1351.5 - 2.86E+06 - - - -1.46 - 2.009 0.358 - 187.5 1 2 0 -0.0017 10 0 0 0 1.55E+09 8.87E+08 - - - 4.5683 0.9998 221125_WJC_METTL3_EV_vs_WT_F08.03948.03948.3 0.000151 Oct-36 R.LDGQTPHDER.Q sp|O60264|SMCA5_HUMAN 1 1166.5316 0.5 110289 3948 3 1166.530133 389.8511 SWI\SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A member 5 OS=Homo sapiens OX=9606 GN=SMARCA5 PE=1 SV=1 4.54 1351.6 - 2.69E+06 - - - -1.2704 - 2.128 0.369 - 125.5 1 2 0 -0.0015 10 0 0 0 2.21E+07 4.37E+07 - - - 4.859 0.9778 221125_WJC_METTL3_EV_vs_WT_F08.03949.03949.2 0.00198 16-Aug R.GEADR[166.11]DTYR[166.11].R "sp|P46783|RS10_HUMAN,tr|F6U211|F6U211_HUMAN,tr|A0A1W2PQS6|A0A1W2PQS6_HUMAN,tr|A0A2R8YFH6|A0A2R8YFH6_HUMAN,tr|A0A2R8Y7H1|A0A2R8Y7H1_HUMAN,tr|S4R435|S4R435_HUMAN" 6 1101.4954 1.37 110290 3949 2 1101.494094 551.755 40S ribosomal protein S10 OS=Homo sapiens OX=9606 GN=RPS10 PE=1 SV=1 4.56 1351.6 - 2.01E+06 - - - -1.1775 - 1.571 0.223 - 166.5 1 2 1 -0.0013 9 0 0 0 8.90E+08 6.48E+08 - - - 1.9945 0.9513 221125_WJC_METTL3_EV_vs_WT_F08.03951.03951.2 0.241 14-Jul R.SKAEEQFK.F sp|Q96J01|THOC3_HUMAN 1 965.4818 0.65 110292 3951 2 965.481412 483.7482 THO complex subunit 3 OS=Homo sapiens OX=9606 GN=THOC3 PE=1 SV=1 5.86 1351.8 - 1.00E+06 - - - -0.4133 - 1.157 0.23 - 101.4 1 2 1 -0.0004 8 0 0 0 1.43E+07 2.18E+07 - - - 1.1795 0.9976 221125_WJC_METTL3_EV_vs_WT_F08.03952.03952.2 0.000504 20-Jul K.NVATEGTSTQK.E "sp|Q9GZR7|DDX24_HUMAN,tr|G3V529|G3V529_HUMAN" 2 1134.5517 0.7 110293 3952 2 1134.555989 568.2831 ATP-dependent RNA helicase DDX24 OS=Homo sapiens OX=9606 GN=DDX24 PE=1 SV=1 6 1351.9 - 554823 - - - 3.7971 - 1.49 0.472 - 98.4 1 2 0 0.0043 11 0 0 0 4.93E+06 7.03E+06 - - - 3.6046 0.9997 221125_WJC_METTL3_EV_vs_WT_F08.03955.03955.2 0.0123 20-Sep R.RPEGAPAPAAR.A sp|Q5VSG8|MANEL_HUMAN 1 1091.5836 2 110296 3955 2 1091.582654 546.7991 "Glycoprotein endo-alpha-1,2-mannosidase-like protein OS=Homo sapiens OX=9606 GN=MANEAL PE=2 SV=1" 9.6 1352.3 - 365110 - - - -0.8584 - 1.993 0.37 - 97.5 1 2 0 -0.0009 11 0 0 0 5.96E+06 2.98E+06 - - - 3.6392 0.9963 221125_WJC_METTL3_EV_vs_WT_F08.03958.03958.2 0.188 16-Aug R.GASDEEIKR.A "sp|P25685|DNJB1_HUMAN,tr|M0QXK0|M0QXK0_HUMAN" 2 1003.4934 0.51 110299 3958 2 1003.49501 502.754 DnaJ homolog subfamily B member 1 OS=Homo sapiens OX=9606 GN=DNAJB1 PE=1 SV=4 4.68 1352.7 - 226949 - - - 1.5665 - 1.44 0.225 - 239.1 1 2 0 0.0016 9 0 0 0 3.80E+06 7.41E+06 - - - 1.7573 0.9998 221125_WJC_METTL3_EV_vs_WT_F08.03962.03962.2 0.00011 18-Sep R.AAQMHSGYQR.R sp|Q96PK6|RBM14_HUMAN 1 1147.5193 1.79 110301 3962 2 1147.518068 574.7669 RNA-binding protein 14 OS=Homo sapiens OX=9606 GN=RBM14 PE=1 SV=2 8.8 1353.1 - 3.80E+06 - - - -1.0527 - 1.981 0.456 - 342.6 1 2 0 -0.0012 10 0 0 0 2.16E+08 1.20E+08 - - - 4.3168 0.9998 221125_WJC_METTL3_EV_vs_WT_F08.03963.03963.2 7.14E-06 18-Oct R.AAQMHSGYQR[166.11].R sp|Q96PK6|RBM14_HUMAN 1 1157.5275 1.79 110302 3963 2 1157.526169 579.771 RNA-binding protein 14 OS=Homo sapiens OX=9606 GN=RBM14 PE=1 SV=2 8.8 1353.2 - 2.80E+06 - - - -1.1896 - 2.047 0.476 - 424.8 1 2 0 -0.0014 10 0 0 0 2.16E+08 1.20E+08 - - - 4.5559 0.9759 221125_WJC_METTL3_EV_vs_WT_F08.03964.03964.2 0.12 18-Aug R.EGGQDVPSNK.D "sp|Q9BZK7|TBL1R_HUMAN,tr|A0A1B0GVH3|A0A1B0GVH3_HUMAN,tr|A0A0D9SF63|A0A0D9SF63_HUMAN" 3 1029.4727 1.6 110303 3964 2 1029.474814 515.7436 F-box-like\WD repeat-containing protein TBL1XR1 OS=Homo sapiens OX=9606 GN=TBL1XR1 PE=1 SV=1 4.37 1353.3 - 2.08E+06 - - - 2.0506 - 1.463 0.068 - 144.9 1 2 0 0.0021 10 0 0 0 5.93E+07 3.71E+07 - - - 0.6046 0.966 221125_WJC_METTL3_EV_vs_WT_F08.03965.03965.2 0.0221 16-Sep A.AQMHSGYQR[166.11].R sp|Q96PK6|RBM14_HUMAN 1 1086.4904 1.79 110304 3965 2 1086.489847 544.2525 RNA-binding protein 14 OS=Homo sapiens OX=9606 GN=RBM14 PE=1 SV=2 8.8 1353.3 - 1.82E+06 - - - -0.5384 - 1.406 0.389 - 358.1 1 1 0 -0.0006 9 0 0 0 1.10E+08 6.17E+07 - - - 2.8998 0.9507 221125_WJC_METTL3_EV_vs_WT_F08.03966.03966.2 0.0011 14-Aug A.QMHSGYQR[166.11].R sp|Q96PK6|RBM14_HUMAN 1 1015.4533 2.16 110305 3966 2 1015.45199 508.7339 RNA-binding protein 14 OS=Homo sapiens OX=9606 GN=RBM14 PE=1 SV=2 8.75 1353.4 - 1.23E+06 - - - -1.3078 - 1.349 0.388 - 243.5 1 1 0 -0.0013 8 0 0 0 1.01E+08 4.69E+07 - - - 2.8092 0.9965 221125_WJC_METTL3_EV_vs_WT_F08.03970.03970.2 0.000826 18-Nov K.GQVK[136.11]EEGINK[136.11].S "sp|P09874|PARP1_HUMAN,tr|A0A7I2V3E1|A0A7I2V3E1_HUMAN" 2 1116.611 1.11 110308 3970 2 1116.609063 559.3128 Poly [ADP-ribose] polymerase 1 OS=Homo sapiens OX=9606 GN=PARP1 PE=1 SV=4 6.14 1353.9 - 562837 - - - -1.724 - 2.074 0.43 - 397.9 1 2 1 -0.0019 10 0 0 0 4.57E+06 4.11E+06 - - - 4.2526 0.9994 221125_WJC_METTL3_EV_vs_WT_F08.03975.03975.3 0.0288 13/36 R.SEIQAEQDRK.L "sp|Q16891|MIC60_HUMAN,tr|B9A067|B9A067_HUMAN,tr|C9J406|C9J406_HUMAN,tr|H7C463|H7C463_HUMAN" 4 1202.5891 1.61 110311 3975 3 1202.586633 401.8703 MICOS complex subunit MIC60 OS=Homo sapiens OX=9606 GN=IMMT PE=1 SV=1 4.68 1354.5 - 6.80E+06 - - - -2.0755 - 2.002 0.325 - 252.1 1 2 0 -0.0025 10 0 0 0 2.39E+08 1.48E+08 - - - 4.1899 0.9976 221125_WJC_METTL3_EV_vs_WT_F08.03978.03978.2 0.0268 14-Jul K.SFATASHR[166.11].N "sp|Q9NYF8|BCLF1_HUMAN,tr|E9PKI6|E9PKI6_HUMAN,tr|A0A1W2PQ43|A0A1W2PQ43_HUMAN,tr|E9PK91|E9PK91_HUMAN,tr|E9PK09|E9PK09_HUMAN,tr|E9PQN2|E9PQN2_HUMAN" 6 885.4332 2.78 110314 3978 2 885.432208 443.7239 Bcl-2-associated transcription factor 1 OS=Homo sapiens OX=9606 GN=BCLAF1 PE=1 SV=2 9.49 1354.7 - 923504 - - - -1.1599 - 1.241 0.292 - 168.6 1 2 0 -0.001 8 0 0 0 1.41E+08 5.09E+07 - - - 1.8486 0.9998 221125_WJC_METTL3_EV_vs_WT_F08.03980.03980.2 0.013 18-Dec R.SEIQAEQDRK.L "sp|Q16891|MIC60_HUMAN,tr|B9A067|B9A067_HUMAN,tr|C9J406|C9J406_HUMAN,tr|H7C463|H7C463_HUMAN" 4 1202.5891 1.56 110316 3980 2 1202.588712 602.3018 MICOS complex subunit MIC60 OS=Homo sapiens OX=9606 GN=IMMT PE=1 SV=1 4.68 1355 - 841918 - - - -0.3468 - 2.193 0.44 - 615.8 1 2 0 -0.0004 10 0 0 0 3.69E+07 2.36E+07 - - - 4.4826 0.9639 221125_WJC_METTL3_EV_vs_WT_F08.03981.03981.2 5.25E-05 22-Oct L.TQSVGGDSSADR.L "sp|Q86U44|MTA70_HUMAN,tr|H0YFV6|H0YFV6_HUMAN" 2 1178.5164 0.02 110317 3981 2 1178.514509 590.2655 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 4.21 1355.1 - 708475 - - - -1.5689 - 1.845 0.358 - 365.6 1 1 0 -0.0019 12 0 0 0 7.53E+06 3.33E+08 - - - 3.2961 0.9875 221125_WJC_METTL3_EV_vs_WT_F08.03982.03982.2 0.000338 22-Oct K.AGADEER[166.11]AETAR[166.11].L "sp|P78371|TCPB_HUMAN,tr|F8VQ14|F8VQ14_HUMAN,tr|F5GWF6|F5GWF6_HUMAN" 3 1294.6016 0.65 110318 3982 2 1294.598401 648.3081 T-complex protein 1 subunit beta OS=Homo sapiens OX=9606 GN=CCT2 PE=1 SV=4 4.41 1355.2 - 442714 - - - -2.5073 - 1.675 0.401 - 110.6 1 2 1 -0.0032 12 0 0 0 3.37E+06 5.15E+06 - - - 3.359 0.9988 221125_WJC_METTL3_EV_vs_WT_F08.03987.03987.2 0.00778 16-Aug K.GQDQGPPER[166.11].V sp|Q9NY12|GAR1_HUMAN 1 992.4551 1.41 110321 3987 2 992.452873 497.2348 H\ACA ribonucleoprotein complex subunit 1 OS=Homo sapiens OX=9606 GN=GAR1 PE=1 SV=1 4.37 1355.8 - 2.79E+06 - - - -2.2359 - 1.914 0.292 - 385.1 1 2 0 -0.0022 9 0 0 0 9.95E+07 7.08E+07 - - - 3.0752 0.9759 221125_WJC_METTL3_EV_vs_WT_F08.03990.03990.2 0.0253 14-Aug R.EADR[166.11]DTYR[166.11].R "sp|Q9NQ39|RS10L_HUMAN,sp|P46783|RS10_HUMAN,tr|F6U211|F6U211_HUMAN,tr|A0A1W2PQS6|A0A1W2PQS6_HUMAN,tr|A0A2R8YFH6|A0A2R8YFH6_HUMAN,tr|A0A2R8Y7H1|A0A2R8Y7H1_HUMAN,tr|S4R435|S4R435_HUMAN" 7 1044.4739 2.18 110323 3990 2 1044.471705 523.2442 Putative 40S ribosomal protein S10-like OS=Homo sapiens OX=9606 GN=RPS10P5 PE=5 SV=1 4.56 1356.1 - 2.73E+06 - - - -2.1274 - 1.579 0.273 - 152.9 1 2 1 -0.0022 8 0 0 0 9.05E+07 4.16E+07 - - - 2.4343 0.9426 221125_WJC_METTL3_EV_vs_WT_F08.03994.03994.2 1.1 16-Jul R.GEADRDTYR[166.11].R "sp|P46783|RS10_HUMAN,tr|F6U211|F6U211_HUMAN,tr|A0A1W2PQS6|A0A1W2PQS6_HUMAN,tr|A0A2R8YFH6|A0A2R8YFH6_HUMAN,tr|A0A2R8Y7H1|A0A2R8Y7H1_HUMAN,tr|S4R435|S4R435_HUMAN" 6 1091.4871 - 110327 3994 2 1091.486015 546.7508 40S ribosomal protein S10 OS=Homo sapiens OX=9606 GN=RPS10 PE=1 SV=1 4.56 1356.6 - 750434 - - - -1.0133 - 1.168 0.247 - 107.1 2 2 1 -0.0011 9 0 0 0 - - - - - 1.1798 0.9941 221125_WJC_METTL3_EV_vs_WT_F08.03999.03999.2 0.00435 14-Aug R.EADRDTYR.R "sp|Q9NQ39|RS10L_HUMAN,sp|P46783|RS10_HUMAN,tr|F6U211|F6U211_HUMAN,tr|A0A1W2PQS6|A0A1W2PQS6_HUMAN,tr|A0A2R8YFH6|A0A2R8YFH6_HUMAN,tr|A0A2R8Y7H1|A0A2R8Y7H1_HUMAN,tr|S4R435|S4R435_HUMAN" 7 1024.4574 2.17 110329 3999 2 1024.455829 513.236 Putative 40S ribosomal protein S10-like OS=Homo sapiens OX=9606 GN=RPS10P5 PE=5 SV=1 4.56 1357.2 - 4.62E+06 - - - -1.5208 - 1.629 0.398 - 152.7 1 2 1 -0.0016 8 0 0 0 8.99E+07 4.15E+07 - - - 3.4518 0.9996 221125_WJC_METTL3_EV_vs_WT_F08.04000.04000.3 0.000105 13/44 K.AGADEERAETAR.L "sp|P78371|TCPB_HUMAN,tr|F8VQ14|F8VQ14_HUMAN,tr|F5GWF6|F5GWF6_HUMAN" 3 1274.5851 0.59 110330 4000 3 1274.582084 425.869 T-complex protein 1 subunit beta OS=Homo sapiens OX=9606 GN=CCT2 PE=1 SV=4 4.41 1357.3 - 2.70E+06 - - - -2.3718 - 2.312 0.495 - 246.2 1 2 1 -0.003 12 0 0 0 3.14E+07 5.29E+07 - - - 6.381 0.9997 221125_WJC_METTL3_EV_vs_WT_F08.04004.04004.2 0.00103 16-Dec K.QR[166.11]PSC[160.03]LSEK[136.11].Y "sp|Q9NRA8|4ET_HUMAN,tr|B1AKL6|B1AKL6_HUMAN,tr|B1AKL5|B1AKL5_HUMAN,tr|B1AKL4|B1AKL4_HUMAN" 4 1121.5618 1.2 110334 4004 2 1121.559343 561.7882 Eukaryotic translation initiation factor 4E transporter OS=Homo sapiens OX=9606 GN=EIF4ENIF1 PE=1 SV=2 8.22 1357.7 - 459733 - - - -2.2023 - 2.477 0.41 - 588.4 1 2 0 -0.0025 9 0 0 0 6.84E+07 5.70E+07 - - - 4.6926 0.9995 221125_WJC_METTL3_EV_vs_WT_F08.04012.04012.2 0.0216 24-Nov R.VGSPQPSSSGGEK.R "sp|O94761|RECQ4_HUMAN,tr|V9GYB6|V9GYB6_HUMAN" 2 1215.5731 1.06 110337 4012 2 1215.573022 608.7938 ATP-dependent DNA helicase Q4 OS=Homo sapiens OX=9606 GN=RECQL4 PE=1 SV=2 5.97 1358.7 - 571833 - - - -0.1012 - 1.73 0.34 - 244.8 1 2 0 -0.0001 13 0 0 0 1.58E+07 1.49E+07 - - - 2.959 1 221125_WJC_METTL3_EV_vs_WT_F08.04013.04013.3 0.00021 13/36 K.TSYAQHQQVR[166.11].Q "sp|P61247|RS3A_HUMAN,tr|H0Y8L7|H0Y8L7_HUMAN,tr|D6R9B6|D6R9B6_HUMAN,tr|H0Y9Y4|H0Y9Y4_HUMAN,tr|D6RAS7|D6RAS7_HUMAN,tr|D6RB09|D6RB09_HUMAN,tr|E9PFI5|E9PFI5_HUMAN,tr|D6RAT0|D6RAT0_HUMAN,tr|D6RG13|D6RG13_HUMAN" 9 1226.6032 1.04 110338 4013 3 1226.601379 409.875 40S ribosomal protein S3a OS=Homo sapiens OX=9606 GN=RPS3A PE=1 SV=2 8.44 1358.7 - 2.24E+06 - - - -1.4471 - 2.754 0.432 - 448.3 1 2 0 -0.0018 10 0 0 0 9.73E+07 9.35E+07 - - - 6.3144 0.9672 221125_WJC_METTL3_EV_vs_WT_F08.04021.04021.2 0.287 16-Aug R.EKEALEQQR.Q sp|Q92922|SMRC1_HUMAN 1 1129.5728 5.63 110343 4021 2 1129.571588 565.7937 SWI\SNF complex subunit SMARCC1 OS=Homo sapiens OX=9606 GN=SMARCC1 PE=1 SV=3 4.79 1359.7 - 318913 - - - -1.0296 - 1.514 0.187 - 181.4 1 2 1 -0.0012 9 0 0 0 5.87E+06 1.04E+06 - - - 1.6217 1 221125_WJC_METTL3_EV_vs_WT_F08.04024.04024.3 1.39E-05 Nov-36 K.TSYAQHQQVR.Q "sp|P61247|RS3A_HUMAN,tr|H0Y8L7|H0Y8L7_HUMAN,tr|D6R9B6|D6R9B6_HUMAN,tr|H0Y9Y4|H0Y9Y4_HUMAN,tr|D6RAS7|D6RAS7_HUMAN,tr|D6RB09|D6RB09_HUMAN,tr|E9PFI5|E9PFI5_HUMAN,tr|D6RAT0|D6RAT0_HUMAN,tr|D6RG13|D6RG13_HUMAN" 9 1216.5949 1.04 110344 4024 3 1216.59388 406.5389 40S ribosomal protein S3a OS=Homo sapiens OX=9606 GN=RPS3A PE=1 SV=2 8.44 1360.1 - 6.45E+06 - - - -0.8253 - 2.423 0.432 - 281.6 1 2 0 -0.001 10 0 0 0 9.76E+07 9.42E+07 - - - 5.9407 0.9999 221125_WJC_METTL3_EV_vs_WT_F08.04029.04029.2 2.76E-07 18-Dec K.TSYAQHQQVR[166.11].Q "sp|P61247|RS3A_HUMAN,tr|H0Y8L7|H0Y8L7_HUMAN,tr|D6R9B6|D6R9B6_HUMAN,tr|H0Y9Y4|H0Y9Y4_HUMAN,tr|D6RAS7|D6RAS7_HUMAN,tr|D6RB09|D6RB09_HUMAN,tr|E9PFI5|E9PFI5_HUMAN,tr|D6RAT0|D6RAT0_HUMAN,tr|D6RG13|D6RG13_HUMAN" 9 1226.6032 1.02 110349 4029 2 1226.602321 614.3089 40S ribosomal protein S3a OS=Homo sapiens OX=9606 GN=RPS3A PE=1 SV=2 8.44 1360.5 - 762908 - - - -0.6791 - 2.182 0.529 - 601.5 1 2 0 -0.0008 10 0 0 0 7.44E+06 7.31E+06 - - - 5.1258 0.9992 221125_WJC_METTL3_EV_vs_WT_F08.04035.04035.2 0.0438 16-Jul K.QRPSC[160.03]LSEK.Y "sp|Q9NRA8|4ET_HUMAN,tr|B1AKL6|B1AKL6_HUMAN,tr|B1AKL5|B1AKL5_HUMAN,tr|B1AKL4|B1AKL4_HUMAN" 4 1103.5393 1.2 110353 4035 2 1103.537991 552.7769 Eukaryotic translation initiation factor 4E transporter OS=Homo sapiens OX=9606 GN=EIF4ENIF1 PE=1 SV=2 8.22 1361.3 - 3.83E+06 - - - -1.2251 - 1.842 0.281 - 162 1 2 0 -0.0014 9 0 0 0 6.84E+07 5.70E+07 - - - 2.8833 0.9998 221125_WJC_METTL3_EV_vs_WT_F08.04036.04036.2 0.000941 16-Nov R.KSVLADQGK.S "sp|Q9NYF8|BCLF1_HUMAN,tr|E9PKI6|E9PKI6_HUMAN,tr|A0A1W2PQ43|A0A1W2PQ43_HUMAN,tr|E9PK91|E9PK91_HUMAN,tr|E9PK09|E9PK09_HUMAN,tr|E9PQN2|E9PQN2_HUMAN" 6 944.5291 2.08 110354 4036 2 944.527822 473.2718 Bcl-2-associated transcription factor 1 OS=Homo sapiens OX=9606 GN=BCLAF1 PE=1 SV=2 8.59 1361.4 - 3.82E+06 - - - -1.3478 - 2.357 0.44 - 372.2 1 2 0 -0.0013 9 0 0 0 1.52E+09 7.31E+08 - - - 4.7709 0.9998 221125_WJC_METTL3_EV_vs_WT_F08.04037.04037.2 0.000133 18-Sep K.AITTQNC[160.03]NTK.C "sp|Q15796|SMAD2_HUMAN,tr|K7ESI8|K7ESI8_HUMAN,tr|K7ERC7|K7ERC7_HUMAN,tr|K7EJX0|K7EJX0_HUMAN,tr|K7EL92|K7EL92_HUMAN,tr|B7Z5N5|B7Z5N5_HUMAN" 6 1149.5448 0.84 110355 4037 2 1149.544374 575.7797 Mothers against decapentaplegic homolog 2 OS=Homo sapiens OX=9606 GN=SMAD2 PE=1 SV=1 8.27 1361.4 - 1.67E+06 - - - -0.3897 - 1.954 0.483 - 245 1 2 0 -0.0004 10 0 0 0 1.73E+07 2.06E+07 - - - 4.4781 0.9551 221125_WJC_METTL3_EV_vs_WT_F08.04041.04041.2 0.611 22-Jul K.TRPSAAATAAAR.K sp|Q5C9Z4|NOM1_HUMAN 1 1142.6156 0.76 110359 4041 2 1142.614727 572.3151 Nucleolar MIF4G domain-containing protein 1 OS=Homo sapiens OX=9606 GN=NOM1 PE=1 SV=1 12 1361.9 - 203792 - - - -0.7807 - 1.326 0.051 - 54.6 11 2 0 -0.0009 12 0 0 0 1.90E+06 2.48E+06 - - - -0.3054 0.9922 221125_WJC_METTL3_EV_vs_WT_F08.04046.04046.2 0.221 14-Sep R.R[166.11]GYYNGTK[136.11].F sp|Q9Y3C6|PPIL1_HUMAN 1 975.4893 0.73 110362 4046 2 975.486347 488.7519 Peptidyl-prolyl cis-trans isomerase-like 1 OS=Homo sapiens OX=9606 GN=PPIL1 PE=1 SV=1 9.7 1362.4 - 983253 - - - -3.0262 - 1.704 0.171 - 268.9 1 2 0 -0.003 8 0 0 0 1.28E+07 1.77E+07 - - - 1.9105 0.9342 221125_WJC_METTL3_EV_vs_WT_F08.04144.04144.2 0.447 14-Oct K.KEESLTER.K "sp|Q9Y2R4|DDX52_HUMAN,tr|A0A087X069|A0A087X069_HUMAN,tr|A0A087WTD6|A0A087WTD6_HUMAN,tr|A0A087X1P7|A0A087X1P7_HUMAN" 4 990.4982 1.12 110391 4144 2 990.49192 496.2564 Probable ATP-dependent RNA helicase DDX52 OS=Homo sapiens OX=9606 GN=DDX52 PE=1 SV=3 4.79 1376.4 - 2.73E+06 - - - -6.3291 - 1.622 0.211 - 395 1 2 0 -0.0063 8 0 0 0 3.69E+07 3.29E+07 - - - 2.0562 0.9881 221125_WJC_METTL3_EV_vs_WT_F08.04149.04149.2 0.0111 18-Aug R.SPYGGGR[166.11]PGR[166.11].V sp|P46781|RS9_HUMAN 1 1022.5161 0.7 110393 4149 2 1022.512241 512.2653 40S ribosomal protein S9 OS=Homo sapiens OX=9606 GN=RPS9 PE=1 SV=3 10.83 1376.9 - 1.86E+06 - - - -3.7418 - 1.354 0.285 - 105.8 1 2 0 -0.0038 10 0 0 0 1.98E+07 2.83E+07 - - - 1.9908 0.9909 221125_WJC_METTL3_EV_vs_WT_F08.04152.04152.2 0.00168 20-Nov K.VSSSSSSLGNK[136.11].L "sp|Q96GY0|ZC21A_HUMAN,tr|H0YAP0|H0YAP0_HUMAN" 2 1059.5288 0.55 110396 4152 2 1059.523388 530.7717 Zinc finger C2HC domain-containing protein 1A OS=Homo sapiens OX=9606 GN=ZC2HC1A PE=1 SV=2 8.72 1377.3 - 1.98E+06 - - - -5.0777 - 1.795 0.339 - 315.9 1 2 0 -0.0054 11 0 0 0 1.25E+07 2.25E+07 - - - 3.1257 0.9991 221125_WJC_METTL3_EV_vs_WT_F08.04156.04156.2 0.00125 13/14 R.R[166.11]TEEENLR[166.11].K "sp|P04637|P53_HUMAN,tr|E7ESS1|E7ESS1_HUMAN,tr|J3KP33|J3KP33_HUMAN,tr|A0A087X1Q1|A0A087X1Q1_HUMAN,tr|A0A0U1RQC9|A0A0U1RQC9_HUMAN,tr|A0A087WT22|A0A087WT22_HUMAN,tr|A0A087WXZ1|A0A087WXZ1_HUMAN" 7 1065.5318 0.92 110398 4156 2 1065.527996 533.7732 Cellular tumor antigen p53 OS=Homo sapiens OX=9606 GN=TP53 PE=1 SV=4 4.79 1377.7 - 3.12E+06 - - - -3.5475 - 2.203 0.439 - 447.6 1 2 0 -0.0038 8 0 0 0 4.09E+07 4.43E+07 - - - 4.6643 0.9986 221125_WJC_METTL3_EV_vs_WT_F08.04157.04157.2 0.00218 20-Oct K.VSSSSSSLGNK.L "sp|Q96GY0|ZC21A_HUMAN,tr|H0YAP0|H0YAP0_HUMAN" 2 1051.5146 0.55 110399 4157 2 1051.511049 526.7646 Zinc finger C2HC domain-containing protein 1A OS=Homo sapiens OX=9606 GN=ZC2HC1A PE=1 SV=2 8.72 1377.8 - 2.21E+06 - - - -3.3466 - 1.883 0.415 - 115.1 1 2 0 -0.0035 11 0 0 0 1.25E+07 2.25E+07 - - - 3.8171 0.9749 221125_WJC_METTL3_EV_vs_WT_F08.04165.04165.2 0.0496 12-May R.HSSEDFR[166.11].F "sp|Q8IXT5|RB12B_HUMAN,tr|B9ZVT1|B9ZVT1_HUMAN" 2 886.3809 2.56 110405 4165 2 886.375845 444.1977 RNA-binding protein 12B OS=Homo sapiens OX=9606 GN=RBM12B PE=1 SV=2 5.32 1378.8 - 1.25E+06 - - - -5.6635 - 1.246 0.378 - 69.4 1 2 0 -0.005 7 0 0 0 3.86E+07 1.51E+07 - - - 2.5282 0.9905 221125_WJC_METTL3_EV_vs_WT_F08.04166.04166.2 0.104 14-Aug R.K[136.11]AEDFGNR[166.11].L "sp|Q9UKM7|MA1B1_HUMAN,tr|A0A804HK28|A0A804HK28_HUMAN,tr|H0YG20|H0YG20_HUMAN,tr|A0A804HKS1|A0A804HKS1_HUMAN,tr|H0YGV7|H0YGV7_HUMAN,tr|A0A804HL65|A0A804HL65_HUMAN,tr|A0A804HIP1|A0A804HIP1_HUMAN,tr|A0A804HK01|A0A804HK01_HUMAN,tr|A0A804HJ23|A0A804HJ23_HUMAN,tr|A0A804HHU1|A0A804HHU1_HUMAN,tr|A0A804HK86|A0A804HK86_HUMAN,tr|A0A804HL61|A0A804HL61_HUMAN,tr|A0A804HJ66|A0A804HJ66_HUMAN,tr|H0YGQ1|H0YGQ1_HUMAN,tr|H0YI64|H0YI64_HUMAN,tr|A0A804HJW0|A0A804HJW0_HUMAN" 16 953.4686 11 110406 4166 2 953.467536 477.7416 "Endoplasmic reticulum mannosyl-oligosaccharide 1,2-alpha-mannosidase OS=Homo sapiens OX=9606 GN=MAN1B1 PE=1 SV=2" 6.07 1378.9 - 963373 - - - -1.0782 - 1.666 0.048 - 175.2 2 2 0 -0.001 8 0 0 0 1.13E+08 1.02E+07 - - - 0.8002 0.9995 221125_WJC_METTL3_EV_vs_WT_F08.04168.04168.2 0.000137 20-Sep K.QEMASASSSQR[166.11].G "sp|Q32P51|RA1L2_HUMAN,sp|P09651|ROA1_HUMAN,tr|A0A7I2YQX9|A0A7I2YQX9_HUMAN,tr|A0A7I2V334|A0A7I2V334_HUMAN,tr|F8VZ49|F8VZ49_HUMAN,tr|A0A7I2V3R8|A0A7I2V3R8_HUMAN,tr|A0A7I2V5T1|A0A7I2V5T1_HUMAN,tr|F8VTQ5|F8VTQ5_HUMAN,tr|F8W6I7|F8W6I7_HUMAN,tr|H0YH80|H0YH80_HUMAN,tr|A0A7I2V2L6|A0A7I2V2L6_HUMAN,tr|A0A7I2V3W0|A0A7I2V3W0_HUMAN,tr|A0A7I2V5H0|A0A7I2V5H0_HUMAN,tr|A0A2R8Y4L2|A0A2R8Y4L2_HUMAN" 14 1190.5225 2.09 110408 4168 2 1190.519553 596.2685 Heterogeneous nuclear ribonucleoprotein A1-like 2 OS=Homo sapiens OX=9606 GN=HNRNPA1L2 PE=2 SV=2 6 1379.1 - 2.90E+06 - - - -2.4922 - 1.672 0.523 - 240.7 1 2 0 -0.003 11 0 0 0 1.55E+07 7.41E+06 - - - 4.2935 0.8654 221125_WJC_METTL3_EV_vs_WT_F08.04169.04169.2 3.54 22-May K.NPPENSDSGTGK[136.11].K "sp|P55010|IF5_HUMAN,tr|H0YN40|H0YN40_HUMAN" 2 1209.5353 0.02 110409 4169 2 1209.537102 605.7749 Eukaryotic translation initiation factor 5 OS=Homo sapiens OX=9606 GN=EIF5 PE=1 SV=2 4.37 1379.3 - 544836 - - - 1.4824 - 0.978 0.069 - 55.6 4 2 0 0.0018 12 0 0 0 1.30E+05 8.43E+06 - - - -0.7774 0.9998 221125_WJC_METTL3_EV_vs_WT_F08.04170.04170.2 0.000117 22-Sep R.ETPSQENGPTAK[136.11].A sp|O15355|PPM1G_HUMAN 1 1265.5979 0.89 110410 4170 2 1265.59633 633.8062 Protein phosphatase 1G OS=Homo sapiens OX=9606 GN=PPM1G PE=1 SV=1 4.53 1379.4 - 506929 - - - -1.2484 - 1.941 0.49 - 255.4 1 2 0 -0.0016 12 0 0 0 2.29E+07 2.58E+07 - - - 4.4046 0.9994 221125_WJC_METTL3_EV_vs_WT_F08.04172.04172.2 0.00365 20-Sep R.SQNQGSLAQGK[136.11].N "sp|Q9Y2H2|SAC2_HUMAN,tr|A0A3B3IRJ9|A0A3B3IRJ9_HUMAN,tr|A0A3B3ITL0|A0A3B3ITL0_HUMAN,tr|A0A0J9YWP2|A0A0J9YWP2_HUMAN" 4 1124.5666 0.98 110411 4172 2 1124.567264 563.2906 Phosphatidylinositide phosphatase SAC2 OS=Homo sapiens OX=9606 GN=INPP5F PE=1 SV=3 8.47 1379.6 - 769742 - - - 0.6349 - 1.657 0.344 - 294.9 1 2 0 0.0007 11 0 0 0 1.61E+07 1.65E+07 - - - 2.9477 0.9888 221125_WJC_METTL3_EV_vs_WT_F08.04174.04174.3 0.0796 Aug-40 K.TK[136.11]PLATTQPAK[136.11].T "sp|P27816|MAP4_HUMAN,tr|E7EVA0|E7EVA0_HUMAN,tr|H7C4C5|H7C4C5_HUMAN,tr|A0A804HKE7|A0A804HKE7_HUMAN,tr|B5MEG9|B5MEG9_HUMAN" 5 1170.6943 0.4 110412 4174 3 1170.692264 391.2387 Microtubule-associated protein 4 OS=Homo sapiens OX=9606 GN=MAP4 PE=1 SV=3 10 1379.8 - 3.63E+06 - - - -1.7588 - 1.305 0.242 - 84.9 1 2 0 -0.0021 11 0 0 0 1.51E+07 3.80E+07 - - - 1.9937 0.9993 221125_WJC_METTL3_EV_vs_WT_F08.04177.04177.3 1.4 Oct-36 K.NK[136.11]EEAAEYAK[136.11].L "sp|P62753|RS6_HUMAN,tr|A2A3R5|A2A3R5_HUMAN" 2 1167.5743 1.3 110415 4177 3 1167.57238 390.1987 40S ribosomal protein S6 OS=Homo sapiens OX=9606 GN=RPS6 PE=1 SV=1 4.79 1379.9 - 5.10E+06 - - - -1.617 - 2.072 0.404 - 217 1 2 1 -0.0019 10 0 0 0 1.94E+08 1.49E+08 - - - 5.1713 0.9978 221125_WJC_METTL3_EV_vs_WT_F08.04179.04179.2 0.0719 18-Oct K.NK[136.11]EEAAEYAK[136.11].L "sp|P62753|RS6_HUMAN,tr|A2A3R5|A2A3R5_HUMAN" 2 1167.5743 1.14 110417 4179 2 1167.573512 584.7944 40S ribosomal protein S6 OS=Homo sapiens OX=9606 GN=RPS6 PE=1 SV=1 4.79 1380.1 - 2.25E+06 - - - -0.6475 - 2.061 0.421 - 345 1 2 1 -0.0008 10 0 0 0 8.87E+07 7.76E+07 - - - 4.1689 0.9874 221125_WJC_METTL3_EV_vs_WT_F08.04181.04181.2 0.15 18-Jul R.SPYGGGRPGR.V sp|P46781|RS9_HUMAN 1 1002.4995 0.71 110419 4181 2 1002.497418 502.257 40S ribosomal protein S9 OS=Homo sapiens OX=9606 GN=RPS9 PE=1 SV=3 10.83 1380.2 - 1.81E+06 - - - -2.1027 - 1.399 0.162 - 73.7 2 2 0 -0.0021 10 0 0 0 2.00E+07 2.83E+07 - - - 1.0396 0.9964 221125_WJC_METTL3_EV_vs_WT_F08.04184.04184.2 0.013 14-Nov K.RYNVGC[160.03]TK.R "sp|Q8IXK0|PHC2_HUMAN,tr|A0A0A0MSI2|A0A0A0MSI2_HUMAN,tr|B3KPJ4|B3KPJ4_HUMAN" 3 996.4811 16.59 110422 4184 2 996.478193 499.2478 Polyhomeotic-like protein 2 OS=Homo sapiens OX=9606 GN=PHC2 PE=1 SV=1 9.31 1380.4 - 1.46E+06 - - - -2.9173 - 1.836 0.22 - 491.9 1 2 0 -0.0029 8 0 0 0 1.02E+08 6.17E+06 - - - 2.4975 0.9947 221125_WJC_METTL3_EV_vs_WT_F08.04185.04185.2 0.178 14-Jul R.KAEDFGNR.L "sp|Q9UKM7|MA1B1_HUMAN,tr|A0A804HK28|A0A804HK28_HUMAN,tr|H0YG20|H0YG20_HUMAN,tr|A0A804HKS1|A0A804HKS1_HUMAN,tr|H0YGV7|H0YGV7_HUMAN,tr|A0A804HL65|A0A804HL65_HUMAN,tr|A0A804HIP1|A0A804HIP1_HUMAN,tr|A0A804HK01|A0A804HK01_HUMAN,tr|A0A804HJ23|A0A804HJ23_HUMAN,tr|A0A804HHU1|A0A804HHU1_HUMAN,tr|A0A804HK86|A0A804HK86_HUMAN,tr|A0A804HL61|A0A804HL61_HUMAN,tr|A0A804HJ66|A0A804HJ66_HUMAN,tr|H0YGQ1|H0YGQ1_HUMAN,tr|H0YI64|H0YI64_HUMAN,tr|A0A804HJW0|A0A804HJW0_HUMAN" 16 935.4461 14.65 110423 4185 2 935.443585 468.7303 "Endoplasmic reticulum mannosyl-oligosaccharide 1,2-alpha-mannosidase OS=Homo sapiens OX=9606 GN=MAN1B1 PE=1 SV=2" 6.07 1380.5 - 1.42E+06 - - - -2.6821 - 1.457 0.251 - 183.4 1 2 0 -0.0025 8 0 0 0 1.72E+08 1.17E+07 - - - 2.0292 0.8779 221125_WJC_METTL3_EV_vs_WT_F08.04186.04186.2 1.96 16-May K.IYEC[160.03]NQVQK[136.11].F "sp|Q5HY98|ZN766_HUMAN,tr|M0QXI4|M0QXI4_HUMAN,tr|M0R1P9|M0R1P9_HUMAN,tr|G3XAE0|G3XAE0_HUMAN" 4 1188.5689 2.24 110424 4186 2 1188.571038 595.2917 Zinc finger protein 766 OS=Homo sapiens OX=9606 GN=ZNF766 PE=1 SV=1 5.99 1380.6 - 1.42E+06 - - - 1.8341 - 1.048 0.051 - 91.4 2 2 0 0.0022 9 0 0 0 6.21E+07 2.77E+07 - - - -0.5818 0.9944 221125_WJC_METTL3_EV_vs_WT_F08.04188.04188.2 0.578 18-Jul R.SAVPPGADK[136.11]K[136.11].A "sp|P46783|RS10_HUMAN,tr|F6U211|F6U211_HUMAN,tr|A0A1W2PQS6|A0A1W2PQS6_HUMAN,tr|A0A2R8YFH6|A0A2R8YFH6_HUMAN,tr|A0A2R8Y7H1|A0A2R8Y7H1_HUMAN,tr|S4R435|S4R435_HUMAN" 6 984.5575 1.12 110426 4188 2 984.555543 493.286 40S ribosomal protein S10 OS=Homo sapiens OX=9606 GN=RPS10 PE=1 SV=1 8.31 1380.9 - 872484 - - - -1.9826 - 1.504 0.189 - 175.5 1 2 0 -0.002 10 0 0 0 2.96E+07 2.64E+07 - - - 1.5756 0.9989 221125_WJC_METTL3_EV_vs_WT_F08.04190.04190.2 0.434 14-Jun K.K[136.11]EESLTER[166.11].K "sp|Q9Y2R4|DDX52_HUMAN,tr|A0A087X069|A0A087X069_HUMAN,tr|A0A087WTD6|A0A087WTD6_HUMAN,tr|A0A087X1P7|A0A087X1P7_HUMAN" 4 1008.5207 1.12 110428 4190 2 1008.519715 505.2676 Probable ATP-dependent RNA helicase DDX52 OS=Homo sapiens OX=9606 GN=DDX52 PE=1 SV=3 4.79 1381.2 - 625698 - - - -0.936 - 1.433 0.311 - 142.2 1 2 0 -0.0009 8 0 0 0 3.69E+07 3.30E+07 - - - 2.4228 0.9956 221125_WJC_METTL3_EV_vs_WT_F08.04197.04197.2 1.59 14-Sep K.KDESLVSK.A sp|Q8NFH5|NUP35_HUMAN 1 904.4866 1.58 110433 4197 2 904.485986 453.2506 Nucleoporin NUP35 OS=Homo sapiens OX=9606 GN=NUP35 PE=1 SV=1 6.07 1381.9 - 3.68E+06 - - - -0.6368 - 1.479 0.137 - 173.9 1 2 0 -0.0006 8 0 0 0 2.39E+07 1.51E+07 - - - 1.233 0.9998 221125_WJC_METTL3_EV_vs_WT_F08.04198.04198.2 0.000553 16-Nov R.HQGTFTDEK.S sp|Q92922|SMRC1_HUMAN 1 1061.4778 3.9 110434 4198 2 1061.477369 531.7462 SWI\SNF complex subunit SMARCC1 OS=Homo sapiens OX=9606 GN=SMARCC1 PE=1 SV=3 5.32 1381.9 - 2.49E+06 - - - -0.3947 - 1.83 0.475 - 285.6 1 2 0 -0.0004 9 0 0 0 6.68E+07 1.71E+07 - - - 4.2975 0.9996 221125_WJC_METTL3_EV_vs_WT_F08.04200.04200.2 0.00128 18-Oct K.NSQGEEVAQR[166.11].S sp|P20700|LMNB1_HUMAN 1 1126.5242 1.29 110436 4200 2 1126.522543 564.2694 Lamin-B1 OS=Homo sapiens OX=9606 GN=LMNB1 PE=1 SV=2 4.53 1382.1 - 2.37E+06 - - - -1.5011 - 2.022 0.374 - 517.1 1 2 0 -0.0017 10 0 0 0 2.40E+08 1.86E+08 - - - 3.7682 0.9998 221125_WJC_METTL3_EV_vs_WT_F08.04201.04201.2 0.0359 18-Dec K.NSQGEEVAQR.S sp|P20700|LMNB1_HUMAN 1 1116.516 1.29 110437 4201 2 1116.515121 559.2653 Lamin-B1 OS=Homo sapiens OX=9606 GN=LMNB1 PE=1 SV=2 4.53 1382.1 - 2.14E+06 - - - -0.755 - 2.426 0.414 - 713 1 2 0 -0.0008 10 0 0 0 2.40E+08 1.86E+08 - - - 4.5723 0.9999 221125_WJC_METTL3_EV_vs_WT_F08.04202.04202.2 0.000456 13/14 K.HEFQAETK.K sp|Q12931|TRAP1_HUMAN 1 988.4614 1.7 110438 4202 2 988.460971 495.238 "Heat shock protein 75 kDa, mitochondrial OS=Homo sapiens OX=9606 GN=TRAP1 PE=1 SV=3" 5.4 1382.2 - 1.30E+06 - - - -0.4441 - 2.425 0.507 - 665.4 1 2 0 -0.0004 8 0 0 0 1.88E+08 1.10E+08 - - - 5.4572 0.9993 221125_WJC_METTL3_EV_vs_WT_F08.04205.04205.3 0.0299 Dec-40 K.QMLESNK[136.11]DSAK[136.11].L sp|O00203|AP3B1_HUMAN 1 1265.6257 0.56 110441 4205 3 1265.62449 422.8825 AP-3 complex subunit beta-1 OS=Homo sapiens OX=9606 GN=AP3B1 PE=1 SV=3 6.07 1382.4 - 610810 - - - -0.9173 - 2.378 0.337 - 209.7 1 2 1 -0.0012 11 0 0 0 3.07E+06 5.48E+06 - - - 4.7578 0.9996 221125_WJC_METTL3_EV_vs_WT_F08.04206.04206.2 0.000413 16-Jun R.QQQQMEQER.Q "sp|Q15149|PLEC_HUMAN,tr|H0YDN1|H0YDN1_HUMAN" 2 1203.5302 2.04 110442 4206 2 1203.52943 602.7724 Plectin OS=Homo sapiens OX=9606 GN=PLEC PE=1 SV=3 4.53 1382.6 - 476997 - - - -0.668 - 1.599 0.412 - 199.1 1 2 0 -0.0008 9 0 0 0 5.65E+06 2.77E+06 - - - 3.4417 0.9969 221125_WJC_METTL3_EV_vs_WT_F08.04208.04208.2 0.0708 20-Sep K.QLESTQTESNK[136.11].K sp|P33176|KINH_HUMAN 1 1271.6085 3.13 110444 4208 2 1271.612572 636.8115 Kinesin-1 heavy chain OS=Homo sapiens OX=9606 GN=KIF5B PE=1 SV=1 4.53 1382.8 - 323137 - - - 3.2227 - 1.693 0.328 - 325.6 1 2 0 0.0041 11 0 0 0 2.62E+07 8.38E+06 - - - 2.8866 0.984 221125_WJC_METTL3_EV_vs_WT_F08.04209.04209.2 6.93E-05 22-Nov K.GSETPGATPGSK.L sp|O75533|SF3B1_HUMAN 1 1087.5146 1.26 110445 4209 2 1087.522197 544.7646 Splicing factor 3B subunit 1 OS=Homo sapiens OX=9606 GN=SF3B1 PE=1 SV=3 6 1383 - 306875 - - - 7.0151 - 2.014 0.408 - 402.2 1 2 0 0.0076 12 0 0 0 8.72E+07 6.94E+07 - - - 3.8942 0.9992 221125_WJC_METTL3_EV_vs_WT_F08.04216.04216.3 0.00127 Nov-36 K.NKEEAAEYAK.L "sp|P62753|RS6_HUMAN,tr|A2A3R5|A2A3R5_HUMAN" 2 1151.5459 1.29 110450 4216 3 1151.544888 384.8559 40S ribosomal protein S6 OS=Homo sapiens OX=9606 GN=RPS6 PE=1 SV=1 4.79 1383.8 - 2.46E+07 - - - -0.851 - 1.95 0.374 - 278.3 1 2 1 -0.001 10 0 0 0 1.94E+08 1.51E+08 - - - 4.6598 0.9998 221125_WJC_METTL3_EV_vs_WT_F08.04217.04217.2 0.000787 18-Oct R.NNTITTTSSK[136.11].R "sp|O75179|ANR17_HUMAN,tr|H0YM23|H0YM23_HUMAN" 2 1073.5444 2.99 110451 4217 2 1073.543422 537.7795 Ankyrin repeat domain-containing protein 17 OS=Homo sapiens OX=9606 GN=ANKRD17 PE=1 SV=3 8.75 1383.9 - 1.67E+06 - - - -0.9278 - 2.199 0.471 - 533.6 1 2 0 -0.001 10 0 0 0 6.95E+07 2.33E+07 - - - 4.719 0.9999 221125_WJC_METTL3_EV_vs_WT_F08.04220.04220.3 0.00479 16/40 R.LAQEEESEAKR.L "sp|O00541|PESC_HUMAN,tr|B3KXD6|B3KXD6_HUMAN,tr|B5MCF9|B5MCF9_HUMAN,tr|H7C267|H7C267_HUMAN" 4 1288.6259 0.99 110454 4220 3 1288.625324 430.5492 Pescadillo homolog OS=Homo sapiens OX=9606 GN=PES1 PE=1 SV=1 4.49 1384.1 - 1.03E+06 - - - -0.454 - 2.686 0.395 - 545.9 1 2 0 -0.0006 11 0 0 0 4.43E+07 4.46E+07 - - - 5.7506 0.9991 221125_WJC_METTL3_EV_vs_WT_F08.04224.04224.2 0.02 14-Aug K.EEHLC[160.03]TQR[166.11].M "tr|A0A087WWU8|A0A087WWU8_HUMAN,tr|J3KN67|J3KN67_HUMAN" 2 1081.485 0.79 110458 4224 2 1081.48304 541.7498 Tropomyosin alpha-3 chain OS=Homo sapiens OX=9606 GN=TPM3 PE=1 SV=1 5.4 1384.7 - 353344 - - - -1.8234 - 1.538 0.373 - 301 1 2 0 -0.002 8 0 0 0 1.56E+07 1.96E+07 - - - 3.0937 0.9903 221125_WJC_METTL3_EV_vs_WT_F08.04230.04230.2 0.01 14-Aug K.EK[136.11]QDVLQK[136.11].L "sp|Q15643|TRIPB_HUMAN,tr|H0YJ97|H0YJ97_HUMAN" 2 1002.5681 1.07 110462 4230 2 1002.566574 502.2913 Thyroid receptor-interacting protein 11 OS=Homo sapiens OX=9606 GN=TRIP11 PE=1 SV=3 6.17 1385.3 - 2.23E+06 - - - -1.4822 - 1.688 0.308 - 202.9 1 2 1 -0.0015 8 0 0 0 5.72E+07 5.32E+07 - - - 2.8944 0.9999 221125_WJC_METTL3_EV_vs_WT_F08.04232.04232.2 9.63E-07 14/22 K.AAHGC[160.03]VTAVSGK.A "sp|O75410|TACC1_HUMAN,tr|E5RFM9|E5RFM9_HUMAN,tr|R4GMT7|R4GMT7_HUMAN" 3 1156.5659 0.97 110464 4232 2 1156.564103 579.2902 Transforming acidic coiled-coil-containing protein 1 OS=Homo sapiens OX=9606 GN=TACC1 PE=1 SV=2 8.27 1385.5 - 1.28E+06 - - - -1.5468 - 2.438 0.554 - 565.3 1 2 0 -0.0018 12 0 0 0 8.42E+06 8.68E+06 - - - 5.4771 0.9996 221125_WJC_METTL3_EV_vs_WT_F08.04234.04234.2 0.000325 20-Dec K.SPAVKPAAAPK.Q "sp|Q14978|NOLC1_HUMAN,tr|A0A0A0MRM9|A0A0A0MRM9_HUMAN" 2 1035.6077 2.42 110466 4234 2 1035.60613 518.8111 Nucleolar and coiled-body phosphoprotein 1 OS=Homo sapiens OX=9606 GN=NOLC1 PE=1 SV=2 10 1385.7 - 1.02E+06 - - - -1.4967 - 2.232 0.349 - 548 1 2 0 -0.0015 11 0 0 0 1.52E+07 6.27E+06 - - - 3.7903 0.999 221125_WJC_METTL3_EV_vs_WT_F08.04238.04238.2 0.0195 14/20 R.LAQEEESEAK[136.11]R[166.11].L "sp|O00541|PESC_HUMAN,tr|B3KXD6|B3KXD6_HUMAN,tr|B5MCF9|B5MCF9_HUMAN,tr|H7C267|H7C267_HUMAN" 4 1306.6484 1.11 110470 4238 2 1306.644896 654.3315 Pescadillo homolog OS=Homo sapiens OX=9606 GN=PES1 PE=1 SV=1 4.49 1386.3 - 378453 - - - -2.6656 - 2.386 0.297 - 1009.4 1 2 0 -0.0035 11 0 0 0 4.76E+06 4.31E+06 - - - 3.5861 0.9957 221125_WJC_METTL3_EV_vs_WT_F08.04244.04244.3 0.000389 16/36 Q.QHPQAAASYR[166.11].G sp|Q96PK6|RBM14_HUMAN 1 1137.5555 0.001 110474 4244 3 1137.553634 380.1924 RNA-binding protein 14 OS=Homo sapiens OX=9606 GN=RBM14 PE=1 SV=2 8.75 1387 - 3.49E+06 - - - -1.6184 - 2.623 0.465 - 656.4 1 1 0 -0.0018 10 0 0 0 0.00E+00 3.67E+07 - - - 6.54 0.9624 221125_WJC_METTL3_EV_vs_WT_F08.04246.04246.2 0.000438 18-Sep Q.QHPQAAASYR[166.11].G sp|Q96PK6|RBM14_HUMAN 1 1137.5555 0.12 110476 4246 2 1137.553293 569.785 RNA-binding protein 14 OS=Homo sapiens OX=9606 GN=RBM14 PE=1 SV=2 8.75 1387.2 - 1.16E+06 - - - -1.9181 - 1.547 0.44 - 258 1 1 0 -0.0022 10 0 0 0 1.68E+06 1.44E+07 - - - 3.508 0.9934 221125_WJC_METTL3_EV_vs_WT_F08.04247.04247.2 0.286 18-Jun R.SAVPPGADKK.A "sp|P46783|RS10_HUMAN,tr|F6U211|F6U211_HUMAN,tr|A0A1W2PQS6|A0A1W2PQS6_HUMAN,tr|A0A2R8YFH6|A0A2R8YFH6_HUMAN,tr|A0A2R8Y7H1|A0A2R8Y7H1_HUMAN,tr|S4R435|S4R435_HUMAN" 6 968.5291 1.59 110477 4247 2 968.528971 485.2718 40S ribosomal protein S10 OS=Homo sapiens OX=9606 GN=RPS10 PE=1 SV=1 8.31 1387.3 - 1.06E+06 - - - -0.128 - 1.317 0.147 - 129 1 2 0 -0.0001 10 0 0 0 2.43E+07 1.53E+07 - - - 0.8953 0.9863 221125_WJC_METTL3_EV_vs_WT_F08.04248.04248.2 0.619 14-Aug K.K[136.11]C[160.03]SESIPK[136.11].D "sp|P09874|PARP1_HUMAN,tr|A0A7I2V384|A0A7I2V384_HUMAN,tr|A0A7I2V5E9|A0A7I2V5E9_HUMAN,tr|A0A7I2V625|A0A7I2V625_HUMAN,tr|A0A7I2V3E1|A0A7I2V3E1_HUMAN" 5 963.503 1.24 110478 4248 2 963.500942 482.7588 Poly [ADP-ribose] polymerase 1 OS=Homo sapiens OX=9606 GN=PARP1 PE=1 SV=4 8.2 1387.4 - 899353 - - - -2.1536 - 1.494 0.102 - 246 1 2 0 -0.0021 8 0 0 0 1.13E+07 9.09E+06 - - - 1.0045 0.9998 221125_WJC_METTL3_EV_vs_WT_F08.04250.04250.2 0.00352 16-Dec R.R[166.11]GDDSFGDK[136.11].Y "sp|P23588|IF4B_HUMAN,tr|E7EX17|E7EX17_HUMAN" 2 1013.4533 2.4 110480 4250 2 1013.452412 507.7339 Eukaryotic translation initiation factor 4B OS=Homo sapiens OX=9606 GN=EIF4B PE=1 SV=2 4.43 1387.7 - 579735 - - - -0.8841 - 2.397 0.407 - 672.1 1 2 0 -0.0009 9 0 0 0 1.53E+08 6.35E+07 - - - 4.576 0.9843 221125_WJC_METTL3_EV_vs_WT_F08.04251.04251.2 1.23 18-Sep K.GPGSRPQISK.E "sp|Q8NDV7|TNR6A_HUMAN,tr|H7C269|H7C269_HUMAN" 2 1025.5618 3.26 110481 4251 2 1025.564461 513.7882 Trinucleotide repeat-containing gene 6A protein OS=Homo sapiens OX=9606 GN=TNRC6A PE=1 SV=2 11 1387.8 - 409132 - - - 2.6025 - 1.665 0.095 - 278.2 1 2 0 0.0027 10 0 0 0 9.09E+06 2.79E+06 - - - 1.1649 0.9281 221125_WJC_METTL3_EV_vs_WT_F08.04255.04255.2 0.345 14-Jun K.EEHLC[160.03]TQR.M "tr|A0A087WWU8|A0A087WWU8_HUMAN,tr|J3KN67|J3KN67_HUMAN" 2 1071.4767 0.78 110483 4255 2 1071.473473 536.7456 Tropomyosin alpha-3 chain OS=Homo sapiens OX=9606 GN=TPM3 PE=1 SV=1 5.4 1388.3 - 1.64E+06 - - - -3.0509 - 1.066 0.143 - 131.6 1 2 0 -0.0033 8 0 0 0 1.53E+07 1.95E+07 - - - 0.2889 0.9993 221125_WJC_METTL3_EV_vs_WT_F08.04259.04259.2 0.00115 20-Aug K.SPAVK[136.11]PAAAPK[136.11].Q "sp|Q14978|NOLC1_HUMAN,tr|A0A0A0MRM9|A0A0A0MRM9_HUMAN" 2 1051.6361 2.42 110487 4259 2 1051.635807 526.8253 Nucleolar and coiled-body phosphoprotein 1 OS=Homo sapiens OX=9606 GN=NOLC1 PE=1 SV=2 10 1388.8 - 484134 - - - -0.2596 - 1.58 0.333 - 225.1 1 2 0 -0.0003 11 0 0 0 1.52E+07 6.27E+06 - - - 2.7379 0.9998 221125_WJC_METTL3_EV_vs_WT_F08.04266.04266.2 0.00982 16-Dec R.RGDDSFGDK.Y "sp|P23588|IF4B_HUMAN,tr|E7EX17|E7EX17_HUMAN" 2 995.4308 2.41 110492 4266 2 995.430218 498.7227 Eukaryotic translation initiation factor 4B OS=Homo sapiens OX=9606 GN=EIF4B PE=1 SV=2 4.43 1389.5 - 7.27E+06 - - - -0.6228 - 2.137 0.384 - 636.1 1 2 0 -0.0006 9 0 0 0 1.53E+08 6.35E+07 - - - 4.074 0.9998 221125_WJC_METTL3_EV_vs_WT_F08.04268.04268.2 3.79E-07 20-Dec K.IHNEMASTSDK.G sp|Q5T3J3|LRIF1_HUMAN 1 1231.5503 11.03 110494 4268 2 1231.547647 616.7824 Ligand-dependent nuclear receptor-interacting factor 1 OS=Homo sapiens OX=9606 GN=LRIF1 PE=1 SV=1 5.32 1389.7 - 308438 - - - -2.155 - 2.35 0.572 - 601 1 2 0 -0.0027 11 0 0 0 4.04E+06 3.67E+05 - - - 5.5764 0.9995 221125_WJC_METTL3_EV_vs_WT_F08.04269.04269.2 0.00285 20-Jun R.EC[160.03]PASGQSEPR[166.11].N sp|Q96RS0|TGS1_HUMAN 1 1226.5225 1.61 110495 4269 2 1226.521536 614.2685 Trimethylguanosine synthase OS=Homo sapiens OX=9606 GN=TGS1 PE=1 SV=3 4.53 1389.8 - 212042 - - - -0.8023 - 1.413 0.415 - 142.1 1 2 0 -0.001 11 0 0 0 1.04E+07 6.47E+06 - - - 3.0411 0.9713 221125_WJC_METTL3_EV_vs_WT_F08.04276.04276.2 0.0313 16-Aug Q.SSSSVPC[160.03]QR.T "sp|Q8WXI9|P66B_HUMAN,tr|A0A0U1RRM1|A0A0U1RRM1_HUMAN,tr|A0A0U1RR30|A0A0U1RR30_HUMAN" 3 1006.4502 0.94 110500 4276 2 1006.450411 504.2324 Transcriptional repressor p66-beta OS=Homo sapiens OX=9606 GN=GATAD2B PE=1 SV=1 7.96 1390.5 - 757071 - - - 0.2166 - 1.597 0.361 - 211.4 1 1 0 0.0002 9 0 0 0 8.10E+06 8.60E+06 - - - 3.0616 0.9993 221125_WJC_METTL3_EV_vs_WT_F08.04279.04279.2 0.00587 18-Aug R.K[136.11]LVEEQNAEK[136.11].A "sp|Q5F1R6|DJC21_HUMAN,tr|A0A2R8Y4N5|A0A2R8Y4N5_HUMAN,tr|A0A2R8Y4Q0|A0A2R8Y4Q0_HUMAN,tr|A0A2R8Y534|A0A2R8Y534_HUMAN" 4 1202.6478 1.54 110503 4279 2 1202.645741 602.3312 DnaJ homolog subfamily C member 21 OS=Homo sapiens OX=9606 GN=DNAJC21 PE=1 SV=2 4.79 1390.9 - 317918 - - - -1.6846 - 1.64 0.375 - 156.9 1 2 0 -0.002 10 0 0 0 4.26E+06 2.76E+06 - - - 3.191 0.9736 221125_WJC_METTL3_EV_vs_WT_F08.04285.04285.2 0.00308 18-Aug F.QVINDGDKPK.V "sp|P0DMV8|HS71A_HUMAN,sp|P0DMV9|HS71B_HUMAN,tr|A0A0G2JIW1|A0A0G2JIW1_HUMAN" 3 1112.5826 0.23 110507 4285 2 1112.581605 557.2986 Heat shock 70 kDa protein 1A OS=Homo sapiens OX=9606 GN=HSPA1A PE=1 SV=1 5.96 1391.4 - 2.63E+06 - - - -0.8835 - 1.686 0.375 - 142.7 1 1 0 -0.001 10 0 0 0 3.01E+07 1.33E+08 - - - 3.2685 0.9996 221125_WJC_METTL3_EV_vs_WT_F08.04287.04287.2 0.00722 20-Sep R.NEGGNSESSLK.N "sp|Q8IWI9|MGAP_HUMAN,tr|H3BP52|H3BP52_HUMAN" 2 1120.4996 0.35 110509 4287 2 1120.4983 561.2571 MAX gene-associated protein OS=Homo sapiens OX=9606 GN=MGA PE=1 SV=4 4.53 1391.7 - 1.17E+06 - - - -1.2012 - 1.627 0.422 - 224.5 1 2 0 -0.0013 11 0 0 0 1.12E+07 3.18E+07 - - - 3.4742 0.9673 221125_WJC_METTL3_EV_vs_WT_F08.04293.04293.2 0.0285 14-Aug V.INDGDK[136.11]PK[136.11].V "sp|P0DMV8|HS71A_HUMAN,sp|P0DMV9|HS71B_HUMAN,tr|A0A0G2JIW1|A0A0G2JIW1_HUMAN" 3 901.484 0.14 110513 4293 2 901.482829 451.7493 Heat shock 70 kDa protein 1A OS=Homo sapiens OX=9606 GN=HSPA1A PE=1 SV=1 5.96 1392.4 - 1.74E+06 - - - -1.2945 - 1.685 0.355 - 151.4 1 1 0 -0.0012 8 0 0 0 2.43E+06 1.75E+07 - - - 3.2363 0.9998 221125_WJC_METTL3_EV_vs_WT_F08.04299.04299.2 0.000293 22-Oct K.GSETPGATPGSK[136.11].L sp|O75533|SF3B1_HUMAN 1 1095.5288 1.27 110518 4299 2 1095.528212 548.7717 Splicing factor 3B subunit 1 OS=Homo sapiens OX=9606 GN=SF3B1 PE=1 SV=3 6 1393.1 - 1.48E+06 - - - -0.5075 - 2.053 0.395 - 317.1 1 2 0 -0.0006 12 0 0 0 8.88E+07 6.97E+07 - - - 3.8509 0.8425 221125_WJC_METTL3_EV_vs_WT_F08.04303.04303.2 1.2 16-May R.LK[136.11]QENPNMR[166.11].L sp|Q96CT7|CC124_HUMAN 1 1146.5934 0.47 110522 4303 2 1146.594497 574.304 Coiled-coil domain-containing protein 124 OS=Homo sapiens OX=9606 GN=CCDC124 PE=1 SV=1 8.75 1393.6 - 317216 - - - 0.9158 - 1.373 0.095 - 71.9 3 2 1 0.001 9 0 0 0 1.40E+06 2.98E+06 - - - 0.4463 0.9999 221125_WJC_METTL3_EV_vs_WT_F08.04307.04307.2 2.77E-05 14/20 R.KLDDTPSGAGK.F "sp|Q9HC52|CBX8_HUMAN,tr|C9J6K3|C9J6K3_HUMAN" 2 1087.551 1.74 110524 4307 2 1087.551237 544.7828 Chromobox protein homolog 8 OS=Homo sapiens OX=9606 GN=CBX8 PE=1 SV=3 5.96 1394.1 - 1.01E+06 - - - 0.2611 - 2.279 0.532 - 579.6 1 2 0 0.0003 11 0 0 0 1.49E+07 8.58E+06 - - - 5.1987 0.786 221125_WJC_METTL3_EV_vs_WT_F08.04308.04308.2 0.115 24-May R.AHPLGDEGGTASK[136.11].K "sp|Q9H7E9|CH033_HUMAN,tr|A0A3B3IRR6|A0A3B3IRR6_HUMAN,tr|A0A3B3ITA3|A0A3B3ITA3_HUMAN,tr|A0A3B3IT54|A0A3B3IT54_HUMAN" 4 1246.6033 0.94 110525 4308 2 1246.594539 624.3089 UPF0488 protein C8orf33 OS=Homo sapiens OX=9606 GN=C8orf33 PE=1 SV=1 5.32 1394.2 - 153963 - - - -7.0512 - 1.053 0.298 - 54.9 1 2 0 -0.0088 13 0 0 0 7.26E+06 7.72E+06 - - - 1.3718 0.9997 221125_WJC_METTL3_EV_vs_WT_F08.04313.04313.2 0.00143 16-Nov R.RGFSANSAR.L "sp|P48668|K2C6C_HUMAN,sp|P04259|K2C6B_HUMAN,sp|P02538|K2C6A_HUMAN" 3 964.4839 408.92 110528 4313 2 964.482581 483.2492 "Keratin, type II cytoskeletal 6C OS=Homo sapiens OX=9606 GN=KRT6C PE=1 SV=3" 12 1394.8 - 1.63E+06 - - - -1.3427 - 1.983 0.417 - 203.2 1 2 0 -0.0013 9 0 0 0 2.68E+09 6.55E+06 - - - 4.1012 0.9487 221125_WJC_METTL3_EV_vs_WT_F08.04317.04317.2 0.0637 12-Aug R.EK[136.11]QEFER[166.11].N "sp|P17480|UBF1_HUMAN,tr|E9PMM2|E9PMM2_HUMAN,tr|E9PKP7|E9PKP7_HUMAN" 3 982.4839 0.28 110532 4317 2 982.480888 492.2492 Nucleolar transcription factor 1 OS=Homo sapiens OX=9606 GN=UBTF PE=1 SV=1 4.79 1395.2 - 742843 - - - -3.0453 - 1.557 0.256 - 253.7 1 2 1 -0.003 7 0 0 0 2.84E+06 1.01E+07 - - - 2.3338 0.9915 221125_WJC_METTL3_EV_vs_WT_F08.04318.04318.2 0.0436 14-Jul R.SQGGWGHR.L sp|Q16610|ECM1_HUMAN 1 883.4049 12.86 110533 4318 2 883.404099 442.7097 Extracellular matrix protein 1 OS=Homo sapiens OX=9606 GN=ECM1 PE=1 SV=2 9.49 1395.3 - 713354 - - - -0.9045 - 1.14 0.188 - 197.7 1 2 0 -0.0008 8 0 0 0 1.11E+07 8.67E+05 - - - 0.8245 0.9844 221125_WJC_METTL3_EV_vs_WT_F08.04319.04319.2 0.00535 18-Oct L.ASDSHR[166.11]PEVK[136.11].L "sp|Q9NYF8|BCLF1_HUMAN,tr|E9PKI6|E9PKI6_HUMAN,tr|A0A1W2PQ43|A0A1W2PQ43_HUMAN,tr|E9PK91|E9PK91_HUMAN,tr|E9PJA7|E9PJA7_HUMAN,tr|E9PK09|E9PK09_HUMAN,tr|E9PQN2|E9PQN2_HUMAN" 7 1142.5799 3.62 110534 4319 2 1142.578916 572.2972 Bcl-2-associated transcription factor 1 OS=Homo sapiens OX=9606 GN=BCLAF1 PE=1 SV=2 6.8 1395.4 - 391897 - - - -0.8656 - 2.12 0.372 - 323.9 1 1 0 -0.001 10 0 0 0 3.02E+07 8.34E+06 - - - 3.8857 0.9997 221125_WJC_METTL3_EV_vs_WT_F08.04324.04324.2 3.70E-05 16-Sep K.GHSNAFQDR.L "sp|Q14241|ELOA1_HUMAN,tr|A0A024RAC6|A0A024RAC6_HUMAN" 2 1030.4581 1.1 110537 4324 2 1030.457161 516.2363 Elongin-A OS=Homo sapiens OX=9606 GN=ELOA PE=1 SV=2 6.74 1396.1 - 1.43E+06 - - - -0.8685 - 1.737 0.449 - 337.4 1 2 0 -0.0009 9 0 0 0 1.68E+07 1.52E+07 - - - 3.9545 0.9761 221125_WJC_METTL3_EV_vs_WT_F08.04326.04326.2 0.916 14-May K.FHPIQGHR[166.11].V sp|Q13151|ROA0_HUMAN 1 1000.5231 2.02 110539 4326 2 1000.522791 501.2688 Heterogeneous nuclear ribonucleoprotein A0 OS=Homo sapiens OX=9606 GN=HNRNPA0 PE=1 SV=1 9.76 1396.3 - 772299 - - - -0.2619 - 1.134 0.084 - 91.2 1 2 0 -0.0003 8 0 0 0 2.69E+07 1.33E+07 - - - 0.0406 0.7942 221125_WJC_METTL3_EV_vs_WT_F08.04334.04334.2 1.08 16-May R.GHVQDPNDR.R "sp|Q14CX7|NAA25_HUMAN,tr|F8VSB9|F8VSB9_HUMAN,tr|F8W0N5|F8W0N5_HUMAN" 3 1036.4686 18.27 110545 4334 2 1036.464329 519.2416 "N-alpha-acetyltransferase 25, NatB auxiliary subunit OS=Homo sapiens OX=9606 GN=NAA25 PE=1 SV=1" 5.21 1397.3 - 9.52E+06 - - - -4.14 - 0.847 0.217 - 41 2 2 0 -0.0043 9 0 0 0 1.51E+08 8.24E+06 - - - 0.0275 0.9995 221125_WJC_METTL3_EV_vs_WT_F08.04335.04335.3 0.00136 Sep-36 R.LQSQTENLKK.Q sp|Q8N1N4|K2C78_HUMAN 1 1187.651 2010.37 110546 4335 3 1187.649888 396.8909 "Keratin, type II cytoskeletal 78 OS=Homo sapiens OX=9606 GN=KRT78 PE=1 SV=2" 8.59 1397.4 - 6.93E+06 - - - -0.9371 - 2.003 0.298 - 77.9 1 2 0 -0.0011 10 0 0 0 2.42E+08 1.20E+05 - - - 3.8908 0.9998 221125_WJC_METTL3_EV_vs_WT_F08.04340.04340.2 0.000231 18-Nov R.LQSQTENLKK.Q sp|Q8N1N4|K2C78_HUMAN 1 1187.651 999 110551 4340 2 1187.650035 594.8328 "Keratin, type II cytoskeletal 78 OS=Homo sapiens OX=9606 GN=KRT78 PE=1 SV=2" 8.59 1397.9 - 915096 - - - -0.8134 - 2.119 0.415 - 358.1 1 2 0 -0.001 10 0 0 0 3.13E+07 0.00E+00 - - - 4.202 0.897 221125_WJC_METTL3_EV_vs_WT_F08.04344.04344.3 0.00468 Oct-36 K.TLSEKETEAR.N sp|P12270|TPR_HUMAN 1 1162.583 2.13 110555 4344 3 1162.573731 388.5349 Nucleoprotein TPR OS=Homo sapiens OX=9606 GN=TPR PE=1 SV=3 4.78 1398.4 - 310804 - - - -7.9564 - 1.956 0.353 - 161.8 1 2 1 -0.0092 10 0 0 0 1.59E+07 7.49E+06 - - - 4.4324 0.9981 221125_WJC_METTL3_EV_vs_WT_F08.04348.04348.2 8.32E-05 14-Sep R.HAIPSAER.G sp|Q92615|LAR4B_HUMAN 1 879.4563 1.33 110557 4348 2 879.455231 440.7354 La-related protein 4B OS=Homo sapiens OX=9606 GN=LARP4B PE=1 SV=3 6.75 1398.9 - 3.34E+06 - - - -1.1757 - 1.716 0.185 - 399.6 1 2 0 -0.001 8 0 0 0 2.72E+07 2.04E+07 - - - 2.0357 0.9987 221125_WJC_METTL3_EV_vs_WT_F08.04349.04349.3 0.07 Nov-40 R.NLEGANQHVSK.E "sp|Q86XP3|DDX42_HUMAN,tr|A0A0A0MSJ0|A0A0A0MSJ0_HUMAN" 2 1195.5945 1.27 110558 4349 3 1195.592144 399.5388 ATP-dependent RNA helicase DDX42 OS=Homo sapiens OX=9606 GN=DDX42 PE=1 SV=1 6.75 1399 - 2.27E+06 - - - -2.0116 - 1.974 0.277 - 174.6 1 2 0 -0.0024 11 0 0 0 1.25E+08 9.83E+07 - - - 3.5596 0.9999 221125_WJC_METTL3_EV_vs_WT_F08.04350.04350.3 0.0222 14/40 R.NLEGANQHVSK[136.11].E "sp|Q86XP3|DDX42_HUMAN,tr|A0A0A0MSJ0|A0A0A0MSJ0_HUMAN" 2 1203.6087 1.27 110559 4350 3 1203.607301 402.2102 ATP-dependent RNA helicase DDX42 OS=Homo sapiens OX=9606 GN=DDX42 PE=1 SV=1 6.75 1399 - 1.84E+06 - - - -1.203 - 2.165 0.377 - 267.4 1 2 0 -0.0014 11 0 0 0 1.25E+08 9.85E+07 - - - 4.9371 0.9966 221125_WJC_METTL3_EV_vs_WT_F08.04353.04353.2 0.00566 18-Sep K.QNSLGSNEEK[136.11].S sp|O75554|WBP4_HUMAN 1 1112.5189 1.61 110562 4353 2 1112.514455 557.2667 WW domain-binding protein 4 OS=Homo sapiens OX=9606 GN=WBP4 PE=1 SV=1 4.53 1399.4 - 403918 - - - -4.0233 - 1.672 0.393 - 308.8 1 2 0 -0.0045 10 0 0 0 7.31E+06 4.53E+06 - - - 3.3771 0.9995 221125_WJC_METTL3_EV_vs_WT_F08.04354.04354.2 0.0111 20-Sep R.NLEGANQHVSK[136.11].E "sp|Q86XP3|DDX42_HUMAN,tr|A0A0A0MSJ0|A0A0A0MSJ0_HUMAN" 2 1203.6087 1.28 110563 4354 2 1203.606879 602.8117 ATP-dependent RNA helicase DDX42 OS=Homo sapiens OX=9606 GN=DDX42 PE=1 SV=1 6.75 1399.5 - 219058 - - - -1.5537 - 1.742 0.393 - 193 1 2 0 -0.0019 11 0 0 0 1.89E+07 1.47E+07 - - - 3.4446 0.9701 221125_WJC_METTL3_EV_vs_WT_F08.04355.04355.2 0.0012 20-Jul M.IASDSHRPEVK.L "sp|Q9NYF8|BCLF1_HUMAN,tr|E9PKI6|E9PKI6_HUMAN,tr|A0A1W2PQ43|A0A1W2PQ43_HUMAN,tr|E9PK91|E9PK91_HUMAN,tr|E9PJA7|E9PJA7_HUMAN,tr|E9PK09|E9PK09_HUMAN,tr|E9PQN2|E9PQN2_HUMAN" 7 1237.6415 0.03 110564 4355 2 1237.64019 619.828 Bcl-2-associated transcription factor 1 OS=Homo sapiens OX=9606 GN=BCLAF1 PE=1 SV=2 6.75 1399.7 - 175723 - - - -1.0577 - 1.709 0.368 - 69.5 1 1 0 -0.0013 11 0 0 0 2.19E+06 6.27E+07 - - - 3.2084 0.997 221125_WJC_METTL3_EV_vs_WT_F08.04359.04359.2 4.14E-06 20-Nov K.EAPAPPK[136.11]AEAK[136.11].A sp|P62750|RL23A_HUMAN 1 1123.6208 0.75 110566 4359 2 1123.619621 562.8177 60S ribosomal protein L23a OS=Homo sapiens OX=9606 GN=RPL23A PE=1 SV=1 6.24 1400.1 - 1.58E+06 - - - -1.0706 - 1.933 0.429 - 377 1 2 1 -0.0012 11 0 0 0 1.59E+07 2.13E+07 - - - 3.9922 0.9995 221125_WJC_METTL3_EV_vs_WT_F08.04361.04361.2 0.00458 20-Nov R.NLEGANQHVSK.E "sp|Q86XP3|DDX42_HUMAN,tr|A0A0A0MSJ0|A0A0A0MSJ0_HUMAN" 2 1195.5945 1.28 110568 4361 2 1195.591702 598.8046 ATP-dependent RNA helicase DDX42 OS=Homo sapiens OX=9606 GN=DDX42 PE=1 SV=1 6.75 1400.3 - 1.01E+06 - - - -2.3812 - 2.295 0.414 - 317.9 1 2 0 -0.0028 11 0 0 0 1.89E+07 1.47E+07 - - - 4.3452 0.9972 221125_WJC_METTL3_EV_vs_WT_F08.04362.04362.2 0.000896 14/18 R.KLQANGPVAK.K "sp|Q14978|NOLC1_HUMAN,tr|S4R3C2|S4R3C2_HUMAN,tr|A0A0A0MRM9|A0A0A0MRM9_HUMAN" 3 1024.6029 2.2 110569 4362 2 1024.597747 513.3087 Nucleolar and coiled-body phosphoprotein 1 OS=Homo sapiens OX=9606 GN=NOLC1 PE=1 SV=2 10 1400.4 - 799430 - - - -5.0576 - 2.469 0.409 - 630.1 1 2 0 -0.0052 10 0 0 0 6.91E+06 3.14E+06 - - - 4.5831 0.9986 221125_WJC_METTL3_EV_vs_WT_F08.04363.04363.2 0.000106 20-Sep K.TIESANQQTDK[136.11].L "sp|O76094|SRP72_HUMAN,tr|R4GNC1|R4GNC1_HUMAN,tr|D6RDY6|D6RDY6_HUMAN" 3 1241.5979 0.68 110570 4363 2 1241.600101 621.8062 Signal recognition particle subunit SRP72 OS=Homo sapiens OX=9606 GN=SRP72 PE=1 SV=3 4.37 1400.6 - 621981 - - - 1.7647 - 1.871 0.269 - 135.6 1 2 0 0.0022 11 0 0 0 4.58E+06 6.77E+06 - - - 2.7219 0.9959 221125_WJC_METTL3_EV_vs_WT_F08.04364.04364.2 0.306 16-Aug R.VSEEENLK[136.11]K[136.11].T sp|Q9Y3B9|RRP15_HUMAN 1 1090.5841 1.24 110571 4364 2 1090.584161 546.2993 RRP15-like protein OS=Homo sapiens OX=9606 GN=RRP15 PE=1 SV=2 4.79 1400.7 - 613691 - - - 0.0523 - 1.307 0.193 - 196.9 1 2 0 0.0001 9 0 0 0 1.05E+07 8.51E+06 - - - 1.2411 0.9976 221125_WJC_METTL3_EV_vs_WT_F08.04367.04367.3 0.00914 Oct-36 K.TLSEK[136.11]ETEAR[166.11].N sp|P12270|TPR_HUMAN 1 1180.6055 2.14 110572 4367 3 1180.603376 394.5424 Nucleoprotein TPR OS=Homo sapiens OX=9606 GN=TPR PE=1 SV=3 4.78 1401.1 - 691018 - - - -1.7576 - 1.775 0.351 - 155.4 1 2 1 -0.0021 10 0 0 0 1.60E+07 7.49E+06 - - - 4.1285 0.9982 221125_WJC_METTL3_EV_vs_WT_F08.04368.04368.2 5.31E-06 20-Oct K.TIESANQQTDK.L "sp|O76094|SRP72_HUMAN,tr|R4GNC1|R4GNC1_HUMAN,tr|D6RDY6|D6RDY6_HUMAN" 3 1233.5837 0.69 110573 4368 2 1233.589011 617.7991 Signal recognition particle subunit SRP72 OS=Homo sapiens OX=9606 GN=SRP72 PE=1 SV=3 4.37 1401.2 - 482899 - - - 4.2972 - 1.861 0.514 - 172.3 1 2 0 0.0053 11 0 0 0 4.68E+06 6.77E+06 - - - 4.516 0.9946 221125_WJC_METTL3_EV_vs_WT_F08.04369.04369.2 0.000796 18-Oct K.SPVVSKPPAK.S "sp|P82094|TMF1_HUMAN,tr|F8WF45|F8WF45_HUMAN,tr|A0A2R8Y7M0|A0A2R8Y7M0_HUMAN" 3 1008.5968 35.65 110574 4369 2 1008.599259 505.3057 TATA element modulatory factor OS=Homo sapiens OX=9606 GN=TMF1 PE=1 SV=2 10 1401.3 - 421846 - - - 2.4569 - 1.765 0.173 - 358.4 1 2 0 0.0025 10 0 0 0 3.45E+06 9.69E+04 - - - 1.9039 0.9878 221125_WJC_METTL3_EV_vs_WT_F08.04378.04378.2 0.0277 16-Jun R.ATNYNAGDR.S "sp|P61626|LYSC_HUMAN,tr|A0A0B4J259|A0A0B4J259_HUMAN,tr|F8VV32|F8VV32_HUMAN" 3 980.4312 16.74 110580 4378 2 980.426195 491.2229 Lysozyme C OS=Homo sapiens OX=9606 GN=LYZ PE=1 SV=1 5.88 1402.4 - 468433 - - - -5.0763 - 1.293 0.413 - 101 1 2 0 -0.005 9 0 0 0 5.31E+06 3.17E+05 - - - 2.8333 0.9854 221125_WJC_METTL3_EV_vs_WT_F08.04380.04380.2 0.0023 18-Jul K.YVHADAPTNK.T "sp|Q92922|SMRC1_HUMAN,tr|F8WE13|F8WE13_HUMAN" 2 1114.5407 0.26 110582 4380 2 1114.547471 558.2776 SWI\SNF complex subunit SMARCC1 OS=Homo sapiens OX=9606 GN=SMARCC1 PE=1 SV=3 6.74 1402.6 - 222048 - - - 6.0545 - 1.539 0.439 - 89.1 2 2 0 0.0067 10 0 0 0 3.69E+06 1.40E+07 - - - 3.3503 0.9993 221125_WJC_METTL3_EV_vs_WT_F08.04385.04385.2 0.149 18-Aug R.LKPTNPAAQK.A "sp|P52948|NUP98_HUMAN,tr|A0A3B3ITD8|A0A3B3ITD8_HUMAN,tr|H0YEN4|H0YEN4_HUMAN,tr|H0YCR0|H0YCR0_HUMAN" 4 1066.6135 2.02 110585 4385 2 1066.613699 534.314 Nuclear pore complex protein Nup98-Nup96 OS=Homo sapiens OX=9606 GN=NUP98 PE=1 SV=4 10 1403.2 - 1.05E+06 - - - 0.1922 - 1.497 0.345 - 113.5 1 2 0 0.0002 10 0 0 0 2.28E+07 1.13E+07 - - - 2.7153 0.9997 221125_WJC_METTL3_EV_vs_WT_F08.04389.04389.2 0.00167 12-Sep R.HWDQNER.F "sp|P08195|4F2_HUMAN,tr|A0A7P0TAN7|A0A7P0TAN7_HUMAN,tr|J3KPF3|J3KPF3_HUMAN,tr|F5H056|F5H056_HUMAN,tr|F5GZI0|F5GZI0_HUMAN,tr|A0A7P0T9F7|A0A7P0T9F7_HUMAN,tr|A0A7P0TBF8|A0A7P0TBF8_HUMAN,tr|A0A7P0Z4A0|A0A7P0Z4A0_HUMAN,tr|F5GZS6|F5GZS6_HUMAN,tr|A0A7P0Z4P5|A0A7P0Z4P5_HUMAN" 10 983.4209 0.81 110589 4389 2 983.421426 492.7177 4F2 cell-surface antigen heavy chain OS=Homo sapiens OX=9606 GN=SLC3A2 PE=1 SV=3 5.32 1403.7 - 405790 - - - 0.4922 - 1.51 0.468 - 256.3 1 2 0 0.0005 7 0 0 0 1.94E+07 2.39E+07 - - - 3.8033 0.9982 221125_WJC_METTL3_EV_vs_WT_F08.04390.04390.2 0.0133 18-Aug R.K[136.11]ILEQQQAAK[136.11].G "sp|Q8N9M1|CS047_HUMAN,tr|J3QS80|J3QS80_HUMAN,tr|A0A804HLH2|A0A804HLH2_HUMAN" 3 1171.6896 1.99 110590 4390 2 1171.688356 586.8521 Uncharacterized protein C19orf47 OS=Homo sapiens OX=9606 GN=C19orf47 PE=1 SV=1 8.59 1403.8 - 319701 - - - -1.0378 - 1.496 0.252 - 164.4 1 2 0 -0.0012 10 0 0 0 7.49E+06 3.77E+06 - - - 2.0262 0.9995 221125_WJC_METTL3_EV_vs_WT_F08.04395.04395.2 0.0318 18-Nov R.KILEQQQAAK.G "sp|Q8N9M1|CS047_HUMAN,tr|J3QS80|J3QS80_HUMAN,tr|A0A804HLH2|A0A804HLH2_HUMAN" 3 1155.6612 2.01 110593 4395 2 1155.660524 578.8379 Uncharacterized protein C19orf47 OS=Homo sapiens OX=9606 GN=C19orf47 PE=1 SV=1 8.59 1404.5 - 576924 - - - -0.5607 - 2.007 0.294 - 374.8 1 2 0 -0.0006 10 0 0 0 7.58E+06 3.77E+06 - - - 3.1568 0.9605 221125_WJC_METTL3_EV_vs_WT_F08.04397.04397.2 0.0956 14-Aug R.HLR[166.11]DEGLR[166.11].L sp|Q9P0L0|VAPA_HUMAN 1 1014.5474 0.85 110595 4397 2 1014.547131 508.281 Vesicle-associated membrane protein-associated protein A OS=Homo sapiens OX=9606 GN=VAPA PE=1 SV=3 6.75 1404.7 - 889923 - - - -0.2326 - 1.449 0.158 - 171.8 1 2 1 -0.0002 8 0 0 0 5.52E+06 6.47E+06 - - - 1.3265 0.9984 221125_WJC_METTL3_EV_vs_WT_F08.04398.04398.2 0.0507 14-Jul K.K[136.11]VGDDIAK[136.11].A sp|P30050|RL12_HUMAN 1 860.4938 1.37 110596 4398 2 860.493996 431.2542 60S ribosomal protein L12 OS=Homo sapiens OX=9606 GN=RPL12 PE=1 SV=1 5.96 1404.8 - 696592 - - - 0.1906 - 1.433 0.255 - 154.1 1 2 0 0.0002 8 0 0 0 1.15E+07 8.44E+06 - - - 2.0094 0.996 221125_WJC_METTL3_EV_vs_WT_F08.04400.04400.2 0.259 16-Jul K.GQLHVDGQK[136.11].L sp|O15067|PUR4_HUMAN 1 988.5181 0.32 110598 4400 2 988.518747 495.2663 Phosphoribosylformylglycinamidine synthase OS=Homo sapiens OX=9606 GN=PFAS PE=1 SV=4 6.74 1405 - 445895 - - - 0.611 - 1.345 0.225 - 126.8 3 2 0 0.0006 9 0 0 0 3.38E+06 1.06E+07 - - - 1.347 0.9978 221125_WJC_METTL3_EV_vs_WT_F08.04403.04403.2 0.032 26-Jun R.LATGEEEGGGSSSK.R sp|P00519|ABL1_HUMAN 1 1307.5841 -1 110601 4403 2 1307.582329 654.7993 Tyrosine-protein kinase ABL1 OS=Homo sapiens OX=9606 GN=ABL1 PE=1 SV=4 4.25 1405.4 - 86171.2 - - - -1.3575 - 1.19 0.343 - 84.2 1 2 0 -0.0018 14 0 0 0 0.00E+00 0.00E+00 - - - 2.0104 0.9998 221125_WJC_METTL3_EV_vs_WT_F08.04409.04409.2 1.47E-05 18-Oct K.NNLPSNDSSK.F "sp|P17480|UBF1_HUMAN,tr|E9PMM2|E9PMM2_HUMAN,tr|E9PKP7|E9PKP7_HUMAN" 3 1074.4942 1.5 110605 4409 2 1074.494073 538.2544 Nucleolar transcription factor 1 OS=Homo sapiens OX=9606 GN=UBTF PE=1 SV=1 5.84 1406 - 1.88E+06 - - - -0.0866 - 1.642 0.507 - 333.5 1 2 0 -0.0001 10 0 0 0 2.17E+07 1.44E+07 - - - 4.1699 0.9998 221125_WJC_METTL3_EV_vs_WT_F08.04410.04410.2 0.000101 20-Dec K.TVEQTATTTNK[136.11].K sp|P08579|RU2B_HUMAN 1 1200.6077 1.23 110606 4410 2 1200.606451 601.3111 U2 small nuclear ribonucleoprotein B'' OS=Homo sapiens OX=9606 GN=SNRPB2 PE=1 SV=1 5.66 1406.1 - 1.19E+06 - - - -1.0786 - 2.32 0.459 - 328.5 1 2 0 -0.0013 11 0 0 0 2.64E+07 2.15E+07 - - - 4.7074 0.9982 221125_WJC_METTL3_EV_vs_WT_F08.04411.04411.2 0.011 18-Jul R.LK[136.11]PTNPAAQK[136.11].A "sp|P52948|NUP98_HUMAN,tr|A0A3B3ITD8|A0A3B3ITD8_HUMAN,tr|H0YEN4|H0YEN4_HUMAN,tr|H0YCR0|H0YCR0_HUMAN" 4 1082.6419 2.01 110607 4411 2 1082.641715 542.3282 Nuclear pore complex protein Nup98-Nup96 OS=Homo sapiens OX=9606 GN=NUP98 PE=1 SV=4 10 1406.2 - 1.13E+06 - - - -0.1653 - 1.136 0.335 - 89.8 1 2 0 -0.0002 10 0 0 0 2.36E+07 1.17E+07 - - - 1.8712 0.9986 221125_WJC_METTL3_EV_vs_WT_F08.04413.04413.2 0.00012 16-Oct K.ANFDKESER.H "sp|Q14974|IMB1_HUMAN,tr|J3KTM9|J3KTM9_HUMAN" 2 1094.4993 1.38 110609 4413 2 1094.498734 548.2569 Importin subunit beta-1 OS=Homo sapiens OX=9606 GN=KPNB1 PE=1 SV=2 4.68 1406.4 - 829427 - - - -0.4733 - 2.013 0.505 - 603.4 1 2 1 -0.0005 9 0 0 0 2.59E+07 1.88E+07 - - - 4.7948 0.9998 221125_WJC_METTL3_EV_vs_WT_F08.04414.04414.3 0.000222 15/40 R.GAKEEHGGLIR.S sp|P26368|U2AF2_HUMAN 1 1165.6204 0.71 110610 4414 3 1165.619421 389.5474 Splicing factor U2AF 65 kDa subunit OS=Homo sapiens OX=9606 GN=U2AF2 PE=1 SV=4 6.76 1406.5 - 687574 - - - -0.8142 - 2.746 0.4 - 270.1 1 2 1 -0.0009 11 0 0 0 5.95E+06 8.40E+06 - - - 5.869 0.9861 221125_WJC_METTL3_EV_vs_WT_F08.04415.04415.2 0.000199 20-Oct A.STSQAQLSSQK.M "sp|Q8IWZ3|ANKH1_HUMAN,tr|A0A0A0MQZ8|A0A0A0MQZ8_HUMAN,tr|H0Y472|H0Y472_HUMAN,tr|H0Y7Y3|H0Y7Y3_HUMAN,tr|H0Y4P6|H0Y4P6_HUMAN,tr|H7C0V5|H7C0V5_HUMAN,tr|H0Y785|H0Y785_HUMAN" 7 1163.5782 1.43 110611 4415 2 1163.578 582.7964 Ankyrin repeat and KH domain-containing protein 1 OS=Homo sapiens OX=9606 GN=ANKHD1 PE=1 SV=1 8.47 1406.6 - 615748 - - - -0.1977 - 1.951 0.408 - 445.7 1 1 0 -0.0002 11 0 0 0 1.06E+07 7.42E+06 - - - 3.8624 0.9367 221125_WJC_METTL3_EV_vs_WT_F08.04419.04419.2 0.0503 18-Aug K.YVHADAPTNK[136.11].T "sp|Q92922|SMRC1_HUMAN,tr|F8WE13|F8WE13_HUMAN" 2 1122.5549 0.18 110615 4419 2 1122.558439 562.2847 SWI\SNF complex subunit SMARCC1 OS=Homo sapiens OX=9606 GN=SMARCC1 PE=1 SV=3 6.74 1407.2 - 294526 - - - 3.1321 - 1.306 0.088 - 91.3 1 2 0 0.0035 10 0 0 0 3.77E+06 2.14E+07 - - - 0.4351 0.964 221125_WJC_METTL3_EV_vs_WT_F08.04420.04420.2 0.275 20-Jul R.QALHSGQNQLK[136.11].E sp|P54886|P5CS_HUMAN 1 1230.656 1.58 110616 4420 2 1230.6525 616.3353 Delta-1-pyrroline-5-carboxylate synthase OS=Homo sapiens OX=9606 GN=ALDH18A1 PE=1 SV=2 8.76 1407.3 - 274563 - - - -2.8716 - 1.529 0.096 - 138.4 3 2 0 -0.0035 11 0 0 0 4.21E+06 2.67E+06 - - - 0.6845 0.9986 221125_WJC_METTL3_EV_vs_WT_F08.04421.04421.2 0.0119 22-Aug R.GTQSTEGSPVSK.M "sp|Q9H4H8|FA83D_HUMAN,tr|A0A087WXK8|A0A087WXK8_HUMAN" 2 1176.5622 0.7 110617 4421 2 1176.559213 589.2884 Protein FAM83D OS=Homo sapiens OX=9606 GN=FAM83D PE=1 SV=3 6 1407.4 - 175481 - - - -2.5778 - 1.508 0.413 - 161.9 1 2 0 -0.003 12 0 0 0 1.26E+06 1.81E+06 - - - 3.1713 1 221125_WJC_METTL3_EV_vs_WT_F08.04427.04427.2 7.51E-06 13/20 K.TVEQTATTTNK.K sp|P08579|RU2B_HUMAN 1 1192.5935 1.23 110622 4427 2 1192.593276 597.304 U2 small nuclear ribonucleoprotein B'' OS=Homo sapiens OX=9606 GN=SNRPB2 PE=1 SV=1 5.66 1408.2 - 5.12E+06 - - - -0.2264 - 2.43 0.588 - 418.9 1 2 0 -0.0003 11 0 0 0 2.64E+07 2.15E+07 - - - 5.7858 0.9985 221125_WJC_METTL3_EV_vs_WT_F08.04429.04429.2 0.000127 16-Dec K.LKQDLNDEK.K "sp|Q15643|TRIPB_HUMAN,tr|H0YJ97|H0YJ97_HUMAN" 2 1101.5666 1.26 110624 4429 2 1101.565835 551.7906 Thyroid receptor-interacting protein 11 OS=Homo sapiens OX=9606 GN=TRIP11 PE=1 SV=3 4.56 1408.3 - 3.15E+06 - - - -0.6972 - 2.473 0.428 - 343.5 1 2 1 -0.0008 9 0 0 0 4.20E+07 3.34E+07 - - - 4.8214 0.9877 221125_WJC_METTL3_EV_vs_WT_F08.04430.04430.2 0.00795 16-Sep K.LK[136.11]QDLNDEK[136.11].K "sp|Q15643|TRIPB_HUMAN,tr|H0YJ97|H0YJ97_HUMAN" 2 1117.595 1.25 110625 4430 2 1117.593234 559.8048 Thyroid receptor-interacting protein 11 OS=Homo sapiens OX=9606 GN=TRIP11 PE=1 SV=3 4.56 1408.3 - 3.10E+06 - - - -1.5829 - 1.723 0.285 - 181.8 1 2 1 -0.0018 9 0 0 0 4.20E+07 3.37E+07 - - - 2.7195 0.9995 221125_WJC_METTL3_EV_vs_WT_F08.04433.04433.2 0.00418 18-Nov K.KLDPAQSASR.E "sp|Q13813|SPTN1_HUMAN,tr|A0A0D9SF54|A0A0D9SF54_HUMAN,tr|A0A0D9SGF6|A0A0D9SGF6_HUMAN" 3 1071.5673 1.18 110628 4433 2 1071.565489 536.7909 "Spectrin alpha chain, non-erythrocytic 1 OS=Homo sapiens OX=9606 GN=SPTAN1 PE=1 SV=3" 8.75 1408.5 - 1.27E+06 - - - -1.6639 - 2.064 0.348 - 451.4 1 2 0 -0.0018 10 0 0 0 3.74E+07 3.17E+07 - - - 3.6335 0.9992 221125_WJC_METTL3_EV_vs_WT_F08.04434.04434.2 6.45E-05 16-Oct R.DSHGVAQVR[166.11].F "sp|P62277|RS13_HUMAN,tr|J3KMX5|J3KMX5_HUMAN,tr|E9PS50|E9PS50_HUMAN" 3 977.4918 1.08 110629 4434 2 977.488964 489.7532 40S ribosomal protein S13 OS=Homo sapiens OX=9606 GN=RPS13 PE=1 SV=2 6.74 1408.6 - 1.17E+06 - - - -2.9136 - 1.654 0.506 - 300 1 2 0 -0.0028 9 0 0 0 1.08E+08 1.00E+08 - - - 4.2332 1 221125_WJC_METTL3_EV_vs_WT_F08.04436.04436.3 5.84E-08 15/44 M.PAPPC[160.03]ASC[160.03]HAAR.A sp|Q7Z7A3|CTU1_HUMAN 1 1293.5707 1.08 110631 4436 3 1293.570535 432.1975 Cytoplasmic tRNA 2-thiolation protein 1 OS=Homo sapiens OX=9606 GN=CTU1 PE=1 SV=1 8.46 1408.8 - 684146 - - - -0.0966 - 2.72 0.611 - 418.1 1 2 0 -0.0001 12 0 0 0 1.59E+07 1.46E+07 - - - 8.1256 0.8984 221125_WJC_METTL3_EV_vs_WT_F08.04444.04444.3 0.0145 Nov-36 A.ARPVIPQKPR.T "sp|Q5VZK9|CARL1_HUMAN,tr|A0A0U1RQQ1|A0A0U1RQQ1_HUMAN" 2 1160.7142 1.05 110637 4444 3 1160.713273 387.912 F-actin-uncapping protein LRRC16A OS=Homo sapiens OX=9606 GN=CARMIL1 PE=1 SV=1 12.01 1409.9 - 7.23E+06 - - - -0.8081 - 1.755 0.276 - 164.5 1 1 0 -0.0009 10 0 0 0 1.47E+08 1.40E+08 - - - 3.2595 0.8988 221125_WJC_METTL3_EV_vs_WT_F08.04445.04445.3 0.521 Sep-40 K.NPSPTTRPVSR.R "sp|Q9ULV3|CIZ1_HUMAN,tr|Q5SYW2|Q5SYW2_HUMAN,tr|F5H2X7|F5H2X7_HUMAN,tr|H0Y5D5|H0Y5D5_HUMAN,tr|A0A0U1RQR2|A0A0U1RQR2_HUMAN,tr|A0A494C0L7|A0A494C0L7_HUMAN,tr|Q9BTG3|Q9BTG3_HUMAN" 7 1210.6418 1.23 110638 4445 3 1210.64064 404.5546 Cip1-interacting zinc finger protein OS=Homo sapiens OX=9606 GN=CIZ1 PE=1 SV=2 12 1409.9 - 2.04E+06 - - - -0.9863 - 1.536 0.061 - 141.3 1 2 0 -0.0012 11 0 0 0 2.17E+07 1.77E+07 - - - 0.439 0.9453 221125_WJC_METTL3_EV_vs_WT_F08.04447.04447.3 8.54E-05 Dec-52 T.ALAAQQQAAGKEEK.S sp|Q96A49|SYAP1_HUMAN 1 1441.7525 1.48 110640 4447 3 1441.752441 481.5914 Synapse-associated protein 1 OS=Homo sapiens OX=9606 GN=SYAP1 PE=1 SV=1 6.19 1410.1 - 1.30E+06 - - - -0.0451 - 2.271 0.386 - 148.4 1 1 1 -0.0001 14 0 0 0 8.37E+06 5.66E+06 - - - 5.0233 1 221125_WJC_METTL3_EV_vs_WT_F08.04448.04448.3 7.79E-05 14/44 M.PAPPC[160.03]ASC[160.03]HAAR[166.11].A sp|Q7Z7A3|CTU1_HUMAN 1 1303.5789 1.35 110641 4448 3 1303.581372 435.5336 Cytoplasmic tRNA 2-thiolation protein 1 OS=Homo sapiens OX=9606 GN=CTU1 PE=1 SV=1 8.46 1410.1 - 1.29E+06 - - - 1.8733 - 2.328 0.519 - 317.6 1 2 0 0.0024 12 0 0 0 2.12E+07 1.57E+07 - - - 6.6679 0.9235 221125_WJC_METTL3_EV_vs_WT_F08.04449.04449.2 0.0917 20-Sep A.STSQAQLSSQK[136.11].M "sp|Q8IWZ3|ANKH1_HUMAN,tr|A0A0A0MQZ8|A0A0A0MQZ8_HUMAN,tr|H0Y472|H0Y472_HUMAN,tr|H0Y7Y3|H0Y7Y3_HUMAN,tr|H0Y4P6|H0Y4P6_HUMAN,tr|H7C0V5|H7C0V5_HUMAN,tr|H0Y785|H0Y785_HUMAN" 7 1171.5924 1.43 110642 4449 2 1171.592696 586.8035 Ankyrin repeat and KH domain-containing protein 1 OS=Homo sapiens OX=9606 GN=ANKHD1 PE=1 SV=1 8.47 1410.2 - 1.07E+06 - - - 0.227 - 1.654 0.232 - 221.2 1 1 0 0.0003 11 0 0 0 1.06E+07 7.42E+06 - - - 2.1157 1 221125_WJC_METTL3_EV_vs_WT_F08.04454.04454.2 4.66E-07 18-Nov R.INC[160.03]EQC[160.03]SSC[160.03]R.N sp|Q7LFL8|CXXC5_HUMAN 1 1312.4958 1.3 110647 4454 2 1312.495828 657.2552 CXXC-type zinc finger protein 5 OS=Homo sapiens OX=9606 GN=CXXC5 PE=1 SV=1 5.98 1410.8 - 300571 - - - -0.0091 - 2.297 0.654 - 613.2 1 2 0 0 10 0 0 0 3.16E+06 2.44E+06 - - - 6.1927 0.9999 221125_WJC_METTL3_EV_vs_WT_F08.04456.04456.2 9.02E-07 18-Nov R.INC[160.03]EQC[160.03]SSC[160.03]R[166.11].N sp|Q7LFL8|CXXC5_HUMAN 1 1322.5041 1.3 110649 4456 2 1322.505667 662.2593 CXXC-type zinc finger protein 5 OS=Homo sapiens OX=9606 GN=CXXC5 PE=1 SV=1 5.98 1411.1 - 166028 - - - 1.1773 - 2.594 0.537 - 833 1 2 0 0.0016 10 0 0 0 3.16E+06 2.44E+06 - - - 5.6675 0.9987 221125_WJC_METTL3_EV_vs_WT_F08.04460.04460.2 0.419 14-Aug R.SEIDNVKK.Q sp|P04264|K2C1_HUMAN 1 931.4975 2945.09 110651 4460 2 931.497581 466.756 "Keratin, type II cytoskeletal 1 OS=Homo sapiens OX=9606 GN=KRT1 PE=1 SV=6" 5.79 1411.6 - 1.09E+07 - - - 0.1288 - 1.453 0.269 - 276.1 1 2 0 0.0001 8 0 0 0 1.65E+09 5.61E+05 - - - 2.1546 0.769 221125_WJC_METTL3_EV_vs_WT_F08.04461.04461.3 0.174 Sep-40 R.EGR[166.11]PPEPTPAK[136.11].R sp|Q9UQ35|SRRM2_HUMAN 1 1195.6316 12.52 110652 4461 3 1195.631001 399.5511 Serine\arginine repetitive matrix protein 2 OS=Homo sapiens OX=9606 GN=SRRM2 PE=1 SV=2 6.24 1411.6 - 1.39E+06 - - - -0.5068 - 1.596 0.004 - 143.3 1 2 0 -0.0006 11 0 0 0 2.71E+08 2.16E+07 - - - -0.0875 0.9999 221125_WJC_METTL3_EV_vs_WT_F08.04471.04471.2 0.000174 14-Nov R.KYDDVTEK.V "sp|P51572|BAP31_HUMAN,tr|A0A2R8Y5M6|A0A2R8Y5M6_HUMAN,tr|C9JM14|C9JM14_HUMAN,tr|C9J0M4|C9J0M4_HUMAN,tr|C9JQ75|C9JQ75_HUMAN,tr|C9JSP1|C9JSP1_HUMAN,tr|C9JMD7|C9JMD7_HUMAN" 7 996.4764 1 110660 4471 2 996.476349 499.2455 B-cell receptor-associated protein 31 OS=Homo sapiens OX=9606 GN=BCAP31 PE=1 SV=3 4.56 1412.6 - 2.11E+06 - - - -0.0421 - 2.348 0.499 - 392.3 1 2 0 0 8 0 0 0 1.77E+07 1.77E+07 - - - 5.3009 0.9916 221125_WJC_METTL3_EV_vs_WT_F08.04482.04482.2 0.00176 13/22 F.SSGSAVVSGGSR.R sp|P35908|K22E_HUMAN 1 1049.5102 61.9 110669 4482 2 1049.510204 525.7624 "Keratin, type II cytoskeletal 2 epidermal OS=Homo sapiens OX=9606 GN=KRT2 PE=1 SV=2" 9.47 1413.9 - 5.00E+06 - - - 0.0505 - 2.357 0.446 - 485.9 1 1 0 0.0001 12 0 0 0 3.73E+08 6.02E+06 - - - 4.5911 0.9862 221125_WJC_METTL3_EV_vs_WT_F08.04487.04487.2 0.756 14-Jul R.R[166.11]EQEELER[166.11].Q "sp|Q14244|MAP7_HUMAN,tr|A0A087WZ40|A0A087WZ40_HUMAN" 2 1107.5423 1.17 110674 4487 2 1107.543272 554.7784 Ensconsin OS=Homo sapiens OX=9606 GN=MAP7 PE=1 SV=1 4.49 1414.4 - 492006 - - - 0.8406 - 1.271 0.105 - 138.7 1 2 0 0.0009 8 0 0 0 1.20E+07 1.02E+07 - - - 0.5395 0.9998 221125_WJC_METTL3_EV_vs_WT_F08.04493.04493.2 3.99E-06 20-Oct K.SLSDSESDDSK[136.11].S "sp|Q13185|CBX3_HUMAN,tr|S4R2Y4|S4R2Y4_HUMAN" 2 1176.4874 1.25 110678 4493 2 1176.486895 589.251 Chromobox protein homolog 3 OS=Homo sapiens OX=9606 GN=CBX3 PE=1 SV=4 3.84 1415.1 - 1.23E+06 - - - -0.3918 - 1.898 0.463 - 199.2 1 2 0 -0.0005 11 0 0 0 1.27E+08 1.02E+08 - - - 4.1941 0.9999 221125_WJC_METTL3_EV_vs_WT_F08.04494.04494.2 0.0185 20-Dec K.SLSDSESDDSK.S "sp|Q13185|CBX3_HUMAN,tr|S4R2Y4|S4R2Y4_HUMAN" 2 1168.4732 1.25 110679 4494 2 1168.472419 585.2439 Chromobox protein homolog 3 OS=Homo sapiens OX=9606 GN=CBX3 PE=1 SV=4 3.84 1415.2 - 2.05E+06 - - - -0.6307 - 2.098 0.542 - 319.7 1 2 0 -0.0007 11 0 0 0 1.28E+08 1.02E+08 - - - 5.0485 0.967 221125_WJC_METTL3_EV_vs_WT_F08.04495.04495.3 0.0049 Sep-32 R.QEEEEVVRK.E sp|Q9BYJ9|YTHD1_HUMAN 1 1144.5724 1.05 110680 4495 3 1144.574302 382.5314 YTH domain-containing family protein 1 OS=Homo sapiens OX=9606 GN=YTHDF1 PE=1 SV=1 4.49 1415.3 - 1.38E+06 - - - 1.6469 - 1.578 0.129 - 131.5 1 2 0 0.0019 9 0 0 0 5.54E+07 5.30E+07 - - - 1.3525 0.9999 221125_WJC_METTL3_EV_vs_WT_F08.04503.04503.3 7.16E-05 Oct-44 K.VAETANEEEVK[136.11]K[136.11].M "sp|P61221|ABCE1_HUMAN,tr|D6R9I9|D6R9I9_HUMAN" 2 1361.7009 1.07 110686 4503 3 1361.700463 454.9076 ATP-binding cassette sub-family E member 1 OS=Homo sapiens OX=9606 GN=ABCE1 PE=1 SV=1 4.49 1416.1 - 2.64E+06 - - - -0.3393 - 2.17 0.433 - 163.9 1 2 0 -0.0005 12 0 0 0 6.04E+07 5.65E+07 - - - 5.5148 0.9997 221125_WJC_METTL3_EV_vs_WT_F08.04505.04505.2 0.587 18-Nov K.VHQLEQEQAR.R "sp|Q9NW68|BSDC1_HUMAN,tr|E9PQA7|E9PQA7_HUMAN" 2 1236.6211 1.57 110688 4505 2 1236.620795 619.3178 BSD domain-containing protein 1 OS=Homo sapiens OX=9606 GN=BSDC1 PE=1 SV=1 5.4 1416.3 - 550746 - - - -0.245 - 1.872 0.372 - 511.3 1 2 0 -0.0003 10 0 0 0 1.03E+07 6.54E+06 - - - 3.5387 0.9998 221125_WJC_METTL3_EV_vs_WT_F08.04508.04508.2 0.00139 22-Sep K.VAETANEEEVK[136.11]K[136.11].M "sp|P61221|ABCE1_HUMAN,tr|D6R9I9|D6R9I9_HUMAN" 2 1361.7009 1.13 110691 4508 2 1361.70117 681.8577 ATP-binding cassette sub-family E member 1 OS=Homo sapiens OX=9606 GN=ABCE1 PE=1 SV=1 4.49 1416.7 - 248457 - - - 0.1799 - 2.02 0.433 - 236.6 1 2 0 0.0002 12 0 0 0 5.19E+06 4.58E+06 - - - 4.089 0.9997 221125_WJC_METTL3_EV_vs_WT_F08.04512.04512.2 0.00129 20-Aug R.FSASSGGGGSR.G "sp|P78344|IF4G2_HUMAN,tr|H0YD99|H0YD99_HUMAN,tr|H0YCF8|H0YCF8_HUMAN,tr|H0YEC5|H0YEC5_HUMAN,tr|H0YDC0|H0YDC0_HUMAN,tr|H0YEN8|H0YEN8_HUMAN,tr|H0Y3P2|H0Y3P2_HUMAN,tr|H0YCH5|H0YCH5_HUMAN,tr|H0YD77|H0YD77_HUMAN,tr|D3DQV9|D3DQV9_HUMAN" 10 968.4312 2.01 110693 4512 2 968.429987 485.2229 Eukaryotic translation initiation factor 4 gamma 2 OS=Homo sapiens OX=9606 GN=EIF4G2 PE=1 SV=1 9.75 1417.2 - 1.90E+06 - - - -1.2236 - 1.671 0.452 - 177.3 1 2 0 -0.0012 11 0 0 0 1.96E+07 9.76E+06 - - - 3.768 0.9999 221125_WJC_METTL3_EV_vs_WT_F08.04513.04513.3 0.00196 Nov-44 K.VAETANEEEVKK.M "sp|P61221|ABCE1_HUMAN,tr|D6R9I9|D6R9I9_HUMAN" 2 1345.6725 1.07 110694 4513 3 1345.672364 449.5648 ATP-binding cassette sub-family E member 1 OS=Homo sapiens OX=9606 GN=ABCE1 PE=1 SV=1 4.49 1417.2 - 4.55E+06 - - - -0.1196 - 2.558 0.409 - 185.7 1 2 0 -0.0002 12 0 0 0 6.05E+07 5.65E+07 - - - 5.7033 0.9962 221125_WJC_METTL3_EV_vs_WT_F08.04514.04514.3 0.197 Aug-32 K.QELEEEQRR.A sp|Q01664|TFAP4_HUMAN 1 1215.5844 2.03 110695 4514 3 1215.58285 406.2021 Transcription factor AP-4 OS=Homo sapiens OX=9606 GN=TFAP4 PE=1 SV=2 4.49 1417.2 - 4.32E+06 - - - -1.257 - 1.603 0.226 - 179.6 1 2 0 -0.0015 9 0 0 0 4.23E+07 2.09E+07 - - - 2.4814 0.9999 221125_WJC_METTL3_EV_vs_WT_F08.04515.04515.3 0.000363 13/40 R.GQLQSHGVQAR.E sp|P98175|RBM10_HUMAN 1 1179.6109 2.7 110696 4515 3 1179.610701 394.2109 RNA-binding protein 10 OS=Homo sapiens OX=9606 GN=RBM10 PE=1 SV=3 9.76 1417.3 - 2.75E+06 - - - -0.1416 - 2.316 0.398 - 403 1 2 0 -0.0002 11 0 0 0 4.04E+08 1.50E+08 - - - 5.3631 0.9999 221125_WJC_METTL3_EV_vs_WT_F08.04518.04518.2 2.73E-05 18-Sep K.C[160.03]TQDLGNSTK[136.11].A sp|Q9Y490|TLN1_HUMAN 1 1130.5117 0.83 110699 4518 2 1130.511651 566.2631 Talin-1 OS=Homo sapiens OX=9606 GN=TLN1 PE=1 SV=3 5.83 1417.6 - 638867 - - - -0.077 - 1.849 0.525 - 356.1 1 2 0 -0.0001 10 0 0 0 5.62E+06 6.80E+06 - - - 4.6343 0.9997 221125_WJC_METTL3_EV_vs_WT_F08.04519.04519.2 0.000789 18-Dec K.VHQLEQEQAR[166.11].R "sp|Q9NW68|BSDC1_HUMAN,tr|E9PQA7|E9PQA7_HUMAN" 2 1246.6294 1.67 110700 4519 2 1246.63211 624.322 BSD domain-containing protein 1 OS=Homo sapiens OX=9606 GN=BSDC1 PE=1 SV=1 5.4 1417.8 - 622624 - - - 2.1995 - 2.223 0.474 - 578.9 1 2 0 0.0027 10 0 0 0 1.09E+07 6.54E+06 - - - 4.771 0.9997 221125_WJC_METTL3_EV_vs_WT_F08.04520.04520.2 0.000322 22-Nov K.EQVAEETSGDSK[136.11].A sp|P35251|RFC1_HUMAN 1 1286.5718 1.26 110701 4520 2 1286.572595 644.2932 Replication factor C subunit 1 OS=Homo sapiens OX=9606 GN=RFC1 PE=1 SV=4 4 1417.9 - 402303 - - - 0.6529 - 2.058 0.395 - 424.3 1 2 0 0.0008 12 0 0 0 5.55E+06 4.42E+06 - - - 3.8572 0.9992 221125_WJC_METTL3_EV_vs_WT_F08.04522.04522.2 0.00213 22-Sep K.EVQTTPSTASNK.V sp|Q7L5N7|PCAT2_HUMAN 1 1261.615 1.83 110703 4522 2 1261.616496 631.8148 Lysophosphatidylcholine acyltransferase 2 OS=Homo sapiens OX=9606 GN=LPCAT2 PE=1 SV=1 6.1 1418.2 - 218939 - - - 1.1779 - 1.553 0.365 - 164.7 1 2 0 0.0015 12 0 0 0 3.14E+06 1.72E+06 - - - 2.8946 0.9787 221125_WJC_METTL3_EV_vs_WT_F08.04523.04523.2 0.0861 26-Jul R.NTKGGDAPAAGEDA.- sp|P62851|RS25_HUMAN 1 1272.5582 1.54 110704 4523 2 1272.557886 637.2864 40S ribosomal protein S25 OS=Homo sapiens OX=9606 GN=RPS25 PE=1 SV=1 4.03 1418.3 - 171408 - - - -0.2648 - 1.268 0.295 - 110.5 1 2 1 -0.0003 14 0 0 0 2.54E+06 1.65E+06 - - - 1.8156 0.9996 221125_WJC_METTL3_EV_vs_WT_F08.04527.04527.3 0.103 13/40 R.GQLQSHGVQAR[166.11].E sp|P98175|RBM10_HUMAN 1 1189.6191 2.7 110706 4527 3 1189.618478 397.547 RNA-binding protein 10 OS=Homo sapiens OX=9606 GN=RBM10 PE=1 SV=3 9.76 1418.9 - 6.71E+06 - - - -0.5548 - 2.239 0.279 - 353 1 2 0 -0.0007 11 0 0 0 4.04E+08 1.50E+08 - - - 3.9402 0.9804 221125_WJC_METTL3_EV_vs_WT_F08.04528.04528.2 0.446 12-Aug K.EREEEFK.T "sp|Q9NYF8|BCLF1_HUMAN,tr|H0YF63|H0YF63_HUMAN,tr|E9PK91|E9PK91_HUMAN,tr|H0YF14|H0YF14_HUMAN" 4 965.4454 2.22 110707 4528 2 965.444963 483.73 Bcl-2-associated transcription factor 1 OS=Homo sapiens OX=9606 GN=BCLAF1 PE=1 SV=2 4.49 1418.9 - 3.00E+06 - - - -0.4785 - 1.468 0.223 - 371 1 2 1 -0.0005 7 0 0 0 4.85E+07 2.18E+07 - - - 1.9043 0.9994 221125_WJC_METTL3_EV_vs_WT_F08.04529.04529.3 0.00784 Oct-36 K.VHQLEQEQAR.R "sp|Q9NW68|BSDC1_HUMAN,tr|E9PQA7|E9PQA7_HUMAN" 2 1236.6211 1.31 110708 4529 3 1236.620772 413.2143 BSD domain-containing protein 1 OS=Homo sapiens OX=9606 GN=BSDC1 PE=1 SV=1 5.4 1419 - 7.68E+06 - - - -0.2636 - 2.043 0.277 - 251.3 1 2 0 -0.0003 10 0 0 0 5.78E+07 4.42E+07 - - - 3.7146 1 221125_WJC_METTL3_EV_vs_WT_F08.04530.04530.3 0.00114 13/36 K.YTQVGPDHNR[166.11].S sp|Q08211|DHX9_HUMAN 1 1195.561 1.01 110709 4530 3 1195.559408 399.5276 ATP-dependent RNA helicase A OS=Homo sapiens OX=9606 GN=DHX9 PE=1 SV=4 6.74 1419 - 2.11E+06 - - - -1.2931 - 2.456 0.475 - 217.5 1 2 0 -0.0015 10 0 0 0 4.15E+08 4.13E+08 - - - 6.4595 0.9999 221125_WJC_METTL3_EV_vs_WT_F08.04531.04531.2 6.28E-05 20-Dec R.GQLQSHGVQAR.E sp|P98175|RBM10_HUMAN 1 1179.6109 2.74 110710 4531 2 1179.611173 590.8127 RNA-binding protein 10 OS=Homo sapiens OX=9606 GN=RBM10 PE=1 SV=3 9.76 1419.1 - 3.48E+06 - - - 0.2586 - 2.015 0.508 - 323.5 1 2 0 0.0003 11 0 0 0 5.91E+07 2.16E+07 - - - 4.6883 0.9984 221125_WJC_METTL3_EV_vs_WT_F08.04532.04532.3 0.00591 Nov-36 K.ETNDK[136.11]AELDR[166.11].Q sp|Q13123|RED_HUMAN 1 1207.58 1.49 110711 4532 3 1207.579514 403.5339 Protein Red OS=Homo sapiens OX=9606 GN=IK PE=1 SV=3 4.32 1419.1 - 1.54E+06 - - - -0.3735 - 2.005 0.316 - 245.5 1 2 1 -0.0005 10 0 0 0 2.04E+07 1.37E+07 - - - 4.0945 0.9999 221125_WJC_METTL3_EV_vs_WT_F08.04536.04536.2 8.59E-05 13/20 R.GQLQSHGVQAR[166.11].E sp|P98175|RBM10_HUMAN 1 1189.6191 2.74 110715 4536 2 1189.618464 595.8168 RNA-binding protein 10 OS=Homo sapiens OX=9606 GN=RBM10 PE=1 SV=3 9.76 1419.6 - 794318 - - - -0.5666 - 2.521 0.431 - 647.9 1 2 0 -0.0007 11 0 0 0 5.91E+07 2.16E+07 - - - 4.7256 0.9999 221125_WJC_METTL3_EV_vs_WT_F08.04541.04541.2 0.00282 22-Dec K.VAETANEEEVKK.M "sp|P61221|ABCE1_HUMAN,tr|D6R9I9|D6R9I9_HUMAN" 2 1345.6725 0.9 110720 4541 2 1345.67108 673.8435 ATP-binding cassette sub-family E member 1 OS=Homo sapiens OX=9606 GN=ABCE1 PE=1 SV=1 4.49 1420.1 - 434863 - - - -1.0738 - 2.801 0.492 - 500.3 1 2 0 -0.0014 12 0 0 0 4.12E+06 4.58E+06 - - - 5.3845 0.9998 221125_WJC_METTL3_EV_vs_WT_F08.04542.04542.2 8.30E-07 22-Dec K.EQVAEETSGDSK.A sp|P35251|RFC1_HUMAN 1 1278.5576 1.26 110721 4542 2 1278.556957 640.2861 Replication factor C subunit 1 OS=Homo sapiens OX=9606 GN=RFC1 PE=1 SV=4 4 1420.3 - 410149 - - - -0.4677 - 2.153 0.419 - 601 1 2 0 -0.0006 12 0 0 0 5.55E+06 4.42E+06 - - - 4.1533 0.9991 221125_WJC_METTL3_EV_vs_WT_F08.04543.04543.2 0.000302 16-Sep K.C[160.03]STPEEIKK.R "sp|P60981|DEST_HUMAN,tr|F6RFD5|F6RFD5_HUMAN" 2 1090.5329 5.32 110722 4543 2 1090.535357 546.2737 Destrin OS=Homo sapiens OX=9606 GN=DSTN PE=1 SV=3 6.14 1420.4 - 387058 - - - 2.2897 - 1.614 0.421 - 267.5 1 2 0 0.0025 9 0 0 0 7.95E+07 1.50E+07 - - - 3.5347 0.9749 221125_WJC_METTL3_EV_vs_WT_F08.04549.04549.2 0.00709 16-Sep Q.LQSHGVQAR.E sp|P98175|RBM10_HUMAN 1 994.5308 1.84 110726 4549 2 994.529778 498.2727 RNA-binding protein 10 OS=Homo sapiens OX=9606 GN=RBM10 PE=1 SV=3 9.76 1420.9 - 3.09E+06 - - - -1.0548 - 1.704 0.382 - 379.9 1 1 0 -0.001 9 0 0 0 3.14E+07 1.70E+07 - - - 3.4041 0.9975 221125_WJC_METTL3_EV_vs_WT_F08.04550.04550.2 0.00238 18-Oct R.SSSSQTQPLK.V sp|Q14789|GOGB1_HUMAN 1 1061.5353 0.76 110727 4550 2 1061.539532 531.7749 Golgin subfamily B member 1 OS=Homo sapiens OX=9606 GN=GOLGB1 PE=1 SV=2 8.47 1421 - 1.08E+06 - - - 3.9839 - 1.962 0.377 - 449.7 1 2 0 0.0042 10 0 0 0 8.84E+06 1.17E+07 - - - 3.7054 0.9996 221125_WJC_METTL3_EV_vs_WT_F08.04551.04551.2 0.00199 18-Aug R.SSSSQTQPLK[136.11].V sp|Q14789|GOGB1_HUMAN 1 1069.5495 0.76 110728 4551 2 1069.548989 535.782 Golgin subfamily B member 1 OS=Homo sapiens OX=9606 GN=GOLGB1 PE=1 SV=2 8.47 1421.1 - 1.01E+06 - - - -0.4806 - 1.753 0.38 - 267.5 1 2 0 -0.0005 10 0 0 0 8.84E+06 1.17E+07 - - - 3.4144 0.9998 221125_WJC_METTL3_EV_vs_WT_F08.04552.04552.2 0.00482 20-Aug K.ASSTSTPEPTR.K "sp|Q8N8S7|ENAH_HUMAN,tr|A0A0U1RRM6|A0A0U1RRM6_HUMAN" 2 1132.536 1.03 110729 4552 2 1132.535284 567.2753 Protein enabled homolog OS=Homo sapiens OX=9606 GN=ENAH PE=1 SV=2 6.05 1421.3 - 653389 - - - -0.6596 - 1.964 0.417 - 219.2 1 2 0 -0.0007 11 0 0 0 8.75E+07 8.53E+07 - - - 3.9467 0.9998 221125_WJC_METTL3_EV_vs_WT_F08.04553.04553.2 0.000102 18-Aug R.KSEASSEFAK.K sp|Q92620|PRP16_HUMAN 1 1082.5244 32.45 110730 4553 2 1082.524804 542.2695 Pre-mRNA-splicing factor ATP-dependent RNA helicase PRP16 OS=Homo sapiens OX=9606 GN=DHX38 PE=1 SV=2 6.14 1421.4 - 295935 - - - 0.3695 - 1.786 0.494 - 170.6 1 2 0 0.0004 10 0 0 0 6.26E+07 1.93E+06 - - - 4.3085 0.9999 221125_WJC_METTL3_EV_vs_WT_F08.04562.04562.2 1.62E-05 18-Nov K.YTQVGPDHNR[166.11].S sp|Q08211|DHX9_HUMAN 1 1195.561 1.28 110736 4562 2 1195.560902 598.7878 ATP-dependent RNA helicase A OS=Homo sapiens OX=9606 GN=DHX9 PE=1 SV=4 6.74 1422.5 - 1.71E+06 - - - -0.0435 - 1.895 0.513 - 501.8 1 2 0 -0.0001 10 0 0 0 7.21E+07 5.63E+07 - - - 4.6143 0.9999 221125_WJC_METTL3_EV_vs_WT_F08.04566.04566.3 0.0138 16/40 R.TVIAQHHVAPR.T sp|Q6ZVX7|FBX50_HUMAN 1 1227.6836 795.42 110738 4566 3 1227.682289 410.2352 F-box only protein 50 OS=Homo sapiens OX=9606 GN=NCCRP1 PE=1 SV=1 9.47 1422.9 - 6.14E+06 - - - -1.0996 - 2.963 0.386 - 437 1 2 0 -0.0014 11 0 0 0 9.54E+07 1.20E+05 - - - 5.9289 0.9998 221125_WJC_METTL3_EV_vs_WT_F08.04568.04568.2 0.0376 12-Sep R.THYDPPR[166.11].K "sp|P55795|HNRH2_HUMAN,sp|P31943|HNRH1_HUMAN,tr|H0YBD7|H0YBD7_HUMAN,tr|H0YB39|H0YB39_HUMAN,tr|E5RGV0|E5RGV0_HUMAN,tr|E9PCY7|E9PCY7_HUMAN,tr|D6RBM0|D6RBM0_HUMAN,tr|G8JLB6|G8JLB6_HUMAN,tr|E7EN40|E7EN40_HUMAN" 9 894.4223 1.13 110740 4568 2 894.421193 448.2184 Heterogeneous nuclear ribonucleoprotein H2 OS=Homo sapiens OX=9606 GN=HNRNPH2 PE=1 SV=1 6.41 1423 - 6.45E+06 - - - -1.2779 - 1.855 0.467 - 379.4 1 2 0 -0.0011 7 0 0 0 1.54E+08 1.36E+08 - - - 4.4477 0.8913 221125_WJC_METTL3_EV_vs_WT_F08.04571.04571.3 0.266 Oct-44 R.QIGASSRPPPNR.T "sp|Q06787|FMR1_HUMAN,tr|R9WNI0|R9WNI0_HUMAN,tr|A8MQB8|A8MQB8_HUMAN,tr|G3V0J0|G3V0J0_HUMAN" 4 1278.6793 1.82 110743 4571 3 1278.674877 427.2337 Synaptic functional regulator FMR1 OS=Homo sapiens OX=9606 GN=FMR1 PE=1 SV=1 12 1423.2 - 810733 - - - -3.445 - 1.481 0.151 - 142.5 1 2 0 -0.0044 12 0 0 0 1.90E+08 1.04E+08 - - - 1.3108 0.9998 221125_WJC_METTL3_EV_vs_WT_F08.04572.04572.2 0.000717 14/20 R.TVIAQHHVAPR.T sp|Q6ZVX7|FBX50_HUMAN 1 1227.6836 999 110744 4572 2 1227.685442 614.8491 F-box only protein 50 OS=Homo sapiens OX=9606 GN=NCCRP1 PE=1 SV=1 9.47 1423.3 - 282600 - - - 1.4686 - 2.74 0.438 - 950.8 1 2 0 0.0018 11 0 0 0 4.80E+06 0.00E+00 - - - 5.0023 0.9997 221125_WJC_METTL3_EV_vs_WT_F08.04575.04575.3 0.00877 Dec-40 K.TTGYSDR[166.11]PTAR[166.11].R sp|Q9NP61|ARFG3_HUMAN 1 1243.606 1.04 110745 4575 3 1243.60545 415.5426 ADP-ribosylation factor GTPase-activating protein 3 OS=Homo sapiens OX=9606 GN=ARFGAP3 PE=1 SV=1 8.41 1423.7 - 4.90E+06 - - - -0.4455 - 2.181 0.321 - 267.2 1 2 0 -0.0006 11 0 0 0 2.31E+08 2.23E+08 - - - 4.3339 0.9998 221125_WJC_METTL3_EV_vs_WT_F08.04579.04579.2 0.000713 16-Aug R.KDPEQEVEK.F "sp|Q9BXP5|SRRT_HUMAN,tr|H7C3A1|H7C3A1_HUMAN" 2 1100.535 1.25 110749 4579 2 1100.535508 551.2748 Serrate RNA effector molecule homolog OS=Homo sapiens OX=9606 GN=SRRT PE=1 SV=1 4.41 1424.2 - 567208 - - - 0.4898 - 1.817 0.437 - 196.2 1 2 0 0.0005 9 0 0 0 2.91E+07 2.32E+07 - - - 3.9962 0.9926 221125_WJC_METTL3_EV_vs_WT_F08.04587.04587.2 1.19 20-Sep K.TTGYSDRPTAR.R sp|Q9NP61|ARFG3_HUMAN 1 1223.5895 1.17 110755 4587 2 1223.589931 612.802 ADP-ribosylation factor GTPase-activating protein 3 OS=Homo sapiens OX=9606 GN=ARFGAP3 PE=1 SV=1 8.41 1425.2 - 1.12E+06 - - - 0.3817 - 1.283 0.156 - 93.4 1 2 0 0.0005 11 0 0 0 2.55E+07 2.19E+07 - - - 0.8672 0.9868 221125_WJC_METTL3_EV_vs_WT_F08.04589.04589.2 0.454 20-Oct K.TTGYSDR[166.11]PTAR[166.11].R sp|Q9NP61|ARFG3_HUMAN 1 1243.606 1.17 110757 4589 2 1243.604208 622.8103 ADP-ribosylation factor GTPase-activating protein 3 OS=Homo sapiens OX=9606 GN=ARFGAP3 PE=1 SV=1 8.41 1425.4 - 841279 - - - -1.4442 - 1.238 0.147 - 137 1 2 0 -0.0018 11 0 0 0 2.55E+07 2.19E+07 - - - 0.7037 0.9997 221125_WJC_METTL3_EV_vs_WT_F08.04590.04590.2 4.84E-05 13/16 R.K[136.11]DPEQEVEK[136.11].F "sp|Q9BXP5|SRRT_HUMAN,tr|H7C3A1|H7C3A1_HUMAN" 2 1116.5634 1.25 110758 4590 2 1116.560524 559.289 Serrate RNA effector molecule homolog OS=Homo sapiens OX=9606 GN=SRRT PE=1 SV=1 4.41 1425.6 - 789709 - - - -2.548 - 2.493 0.481 - 573.9 1 2 0 -0.0028 9 0 0 0 2.91E+07 2.32E+07 - - - 5.2355 0.9996 221125_WJC_METTL3_EV_vs_WT_F08.04595.04595.3 0.0405 Nov-40 K.TTGYSDRPTAR.R sp|Q9NP61|ARFG3_HUMAN 1 1223.5895 1.04 110761 4595 3 1223.587945 408.8704 ADP-ribosylation factor GTPase-activating protein 3 OS=Homo sapiens OX=9606 GN=ARFGAP3 PE=1 SV=1 8.41 1426.1 - 1.87E+07 - - - -1.2414 - 1.877 0.333 - 200.1 1 2 0 -0.0015 11 0 0 0 2.31E+08 2.23E+08 - - - 4.041 0.9995 221125_WJC_METTL3_EV_vs_WT_F08.04596.04596.2 0.0305 12-Sep R.THYDPPR.K "sp|P55795|HNRH2_HUMAN,sp|P31943|HNRH1_HUMAN,tr|H0YBD7|H0YBD7_HUMAN,tr|H0YB39|H0YB39_HUMAN,tr|E5RGV0|E5RGV0_HUMAN,tr|E9PCY7|E9PCY7_HUMAN,tr|D6RBM0|D6RBM0_HUMAN,tr|G8JLB6|G8JLB6_HUMAN,tr|E7EN40|E7EN40_HUMAN" 9 884.4141 1.13 110762 4596 2 884.412732 443.2143 Heterogeneous nuclear ribonucleoprotein H2 OS=Homo sapiens OX=9606 GN=HNRNPH2 PE=1 SV=1 6.41 1426.2 - 5.49E+06 - - - -1.5083 - 1.666 0.399 - 382.7 1 2 0 -0.0013 7 0 0 0 1.51E+08 1.34E+08 - - - 3.6049 0.974 221125_WJC_METTL3_EV_vs_WT_F08.04601.04601.2 5.93E-05 22-Nov Y.STSGSSGLTTGK.L "sp|Q16891|MIC60_HUMAN,tr|B9A067|B9A067_HUMAN,tr|A0A087WYS0|A0A087WYS0_HUMAN,tr|D6RAW4|D6RAW4_HUMAN" 4 1081.5251 1.39 110767 4601 2 1081.522032 541.7698 MICOS complex subunit MIC60 OS=Homo sapiens OX=9606 GN=IMMT PE=1 SV=1 8.47 1426.6 - 633577 - - - -2.8663 - 2.38 0.503 - 518.9 1 1 0 -0.0031 12 0 0 0 1.47E+08 1.06E+08 - - - 5.0367 0.9989 221125_WJC_METTL3_EV_vs_WT_F08.04604.04604.2 0.0612 18-Aug K.EKPVC[160.03]GTTYK.V "sp|Q14444|CAPR1_HUMAN,tr|G3V153|G3V153_HUMAN" 2 1181.5751 0.9 110768 4604 2 1181.57381 591.7948 Caprin-1 OS=Homo sapiens OX=9606 GN=CAPRIN1 PE=1 SV=2 8.27 1427 - 4.93E+06 - - - -1.0579 - 1.447 0.32 - 135 1 2 0 -0.0013 10 0 0 0 1.01E+08 1.12E+08 - - - 2.4355 0.8007 221125_WJC_METTL3_EV_vs_WT_F08.04605.04605.3 1.9 Aug-40 R.GPPPAPR[166.11]PTSR[166.11].Y sp|P51116|FXR2_HUMAN 1 1151.6314 0.001 110769 4605 3 1151.63001 384.8844 Fragile X mental retardation syndrome-related protein 2 OS=Homo sapiens OX=9606 GN=FXR2 PE=1 SV=2 12 1427 - 3.49E+06 - - - -1.2339 - 1.224 0.086 - 93.7 1 2 0 -0.0014 11 0 0 0 0.00E+00 8.17E+07 - - - 0.0726 0.9804 221125_WJC_METTL3_EV_vs_WT_F08.04608.04608.2 9.89E-07 22-Dec Y.STSGSSGLTTGK[136.11].L "sp|Q16891|MIC60_HUMAN,tr|B9A067|B9A067_HUMAN,tr|A0A087WYS0|A0A087WYS0_HUMAN,tr|D6RAW4|D6RAW4_HUMAN" 4 1089.5393 1.39 110772 4608 2 1089.542209 545.7769 MICOS complex subunit MIC60 OS=Homo sapiens OX=9606 GN=IMMT PE=1 SV=1 8.47 1427.2 - 1.79E+06 - - - 2.6406 - 2.512 0.53 - 598 1 1 0 0.0029 12 0 0 0 1.48E+08 1.06E+08 - - - 5.3782 0.9997 221125_WJC_METTL3_EV_vs_WT_F08.04610.04610.2 4.45E-07 14/22 K.NEPQNATGAPGR.N sp|P51148|RAB5C_HUMAN 1 1210.5691 1.26 110774 4610 2 1210.565701 606.2918 Ras-related protein Rab-5C OS=Homo sapiens OX=9606 GN=RAB5C PE=1 SV=2 6 1427.4 - 904095 - - - -2.7772 - 2.468 0.542 - 893.3 1 2 0 -0.0034 12 0 0 0 1.29E+08 1.03E+08 - - - 5.4202 0.999 221125_WJC_METTL3_EV_vs_WT_F08.04614.04614.3 0.00355 Aug-36 K.EKPVC[160.03]GTTYK.V "sp|Q14444|CAPR1_HUMAN,tr|G3V153|G3V153_HUMAN" 2 1181.5751 0.82 110775 4614 3 1181.57394 394.8656 Caprin-1 OS=Homo sapiens OX=9606 GN=CAPRIN1 PE=1 SV=2 8.27 1427.8 - 2.92E+07 - - - -0.9479 - 1.345 0.349 - 96.8 1 2 0 -0.0011 10 0 0 0 3.21E+08 3.94E+08 - - - 3.2963 0.9994 221125_WJC_METTL3_EV_vs_WT_F08.04616.04616.3 0.000617 15/44 R.QIGASSR[166.11]PPPNR[166.11].T "sp|Q06787|FMR1_HUMAN,tr|R9WNI0|R9WNI0_HUMAN,tr|A8MQB8|A8MQB8_HUMAN,tr|G3V0J0|G3V0J0_HUMAN" 4 1298.6958 1.96 110777 4616 3 1298.693747 433.9059 Synaptic functional regulator FMR1 OS=Homo sapiens OX=9606 GN=FMR1 PE=1 SV=1 12 1428.1 - 902842 - - - -1.5978 - 2.1 0.299 - 340.6 1 2 0 -0.0021 12 0 0 0 2.14E+08 1.09E+08 - - - 3.9295 1 221125_WJC_METTL3_EV_vs_WT_F08.04622.04622.2 6.61E-08 16-Dec R.HSDGNLC[160.03]VK[136.11].V "sp|P49458|SRP09_HUMAN,tr|Q659G3|Q659G3_HUMAN,tr|E9PE20|E9PE20_HUMAN,tr|Q6P2S0|Q6P2S0_HUMAN" 4 1036.4851 1.49 110781 4622 2 1036.483933 519.2498 Signal recognition particle 9 kDa protein OS=Homo sapiens OX=9606 GN=SRP9 PE=1 SV=2 6.73 1428.8 - 1.45E+06 - - - -1.1539 - 2.163 0.64 - 344 1 2 0 -0.0012 9 0 0 0 2.66E+08 1.79E+08 - - - 5.9996 0.9999 221125_WJC_METTL3_EV_vs_WT_F08.04624.04624.2 2.92E-06 22-Sep K.NEPQNATGAPGR[166.11].N sp|P51148|RAB5C_HUMAN 1 1220.5773 1.26 110783 4624 2 1220.576696 611.2959 Ras-related protein Rab-5C OS=Homo sapiens OX=9606 GN=RAB5C PE=1 SV=2 6 1429 - 1.58E+06 - - - -0.5219 - 1.877 0.525 - 218.7 1 2 0 -0.0006 12 0 0 0 1.29E+08 1.03E+08 - - - 4.5752 1 221125_WJC_METTL3_EV_vs_WT_F08.04625.04625.2 6.16E-08 13/16 R.HSDGNLC[160.03]VK.V "sp|P49458|SRP09_HUMAN,tr|Q659G3|Q659G3_HUMAN,tr|E9PE20|E9PE20_HUMAN,tr|Q6P2S0|Q6P2S0_HUMAN" 4 1028.4709 1.49 110784 4625 2 1028.470957 515.2427 Signal recognition particle 9 kDa protein OS=Homo sapiens OX=9606 GN=SRP9 PE=1 SV=2 6.73 1429.1 - 1.56E+06 - - - 0.0272 - 2.577 0.644 - 435.4 1 2 0 0 9 0 0 0 2.67E+08 1.79E+08 - - - 6.5362 0.9998 221125_WJC_METTL3_EV_vs_WT_F08.04627.04627.3 0.000246 Dec-48 K.AK[136.11]PAEAPAAAAPK[136.11].A "sp|P36957|ODO2_HUMAN,tr|Q86SW4|Q86SW4_HUMAN" 2 1207.6896 1.19 110786 4627 3 1207.687838 403.5705 "Dihydrolipoyllysine-residue succinyltransferase component of 2-oxoglutarate dehydrogenase complex, mitochondrial OS=Homo sapiens OX=9606 GN=DLST PE=1 SV=4" 8.64 1429.2 - 1.35E+06 - - - -1.4358 - 2.043 0.398 - 164.5 1 2 0 -0.0017 13 0 0 0 4.23E+07 3.57E+07 - - - 4.9138 0.9918 221125_WJC_METTL3_EV_vs_WT_F08.04633.04633.3 0.206 Aug-36 K.EK[136.11]PVC[160.03]GTTYK[136.11].V "sp|Q14444|CAPR1_HUMAN,tr|G3V153|G3V153_HUMAN" 2 1197.6035 0.83 110791 4633 3 1197.602341 400.2084 Caprin-1 OS=Homo sapiens OX=9606 GN=CAPRIN1 PE=1 SV=2 8.27 1429.9 - 4.03E+07 - - - -0.9344 - 1.378 0.22 - 106.1 1 2 0 -0.0011 10 0 0 0 3.20E+08 3.87E+08 - - - 1.9289 1 221125_WJC_METTL3_EV_vs_WT_F08.04635.04635.3 4.82E-05 13/40 K.LC[160.03]VQNSHQEAR.N sp|Q9H0L4|CSTFT_HUMAN 1 1340.6255 3.23 110793 4635 3 1340.625102 447.8825 Cleavage stimulation factor subunit 2 tau variant OS=Homo sapiens OX=9606 GN=CSTF2T PE=1 SV=1 6.74 1430.1 - 3.46E+06 - - - -0.3207 - 2.487 0.5 - 330.3 1 2 0 -0.0004 11 0 0 0 2.56E+07 7.94E+06 - - - 6.7026 1 221125_WJC_METTL3_EV_vs_WT_F08.04637.04637.3 0.00145 Dec-44 R.YIDTEHGGSQAR.F "sp|Q15436|SC23A_HUMAN,tr|F5H365|F5H365_HUMAN" 2 1332.6058 0.62 110795 4637 3 1332.604282 445.2092 Protein transport protein Sec23A OS=Homo sapiens OX=9606 GN=SEC23A PE=1 SV=2 5.32 1430.2 - 988239 - - - -1.1706 - 1.916 0.508 - 166.4 1 2 0 -0.0016 12 0 0 0 9.78E+06 1.58E+07 - - - 6.0056 0.9997 221125_WJC_METTL3_EV_vs_WT_F08.04638.04638.2 0.00313 20-Dec K.SESTGTPGHLR[166.11].S "sp|Q8N573|OXR1_HUMAN,tr|H0YC07|H0YC07_HUMAN" 2 1150.5606 1.14 110796 4638 2 1150.559934 576.2876 Oxidation resistance protein 1 OS=Homo sapiens OX=9606 GN=OXR1 PE=1 SV=2 6.47 1430.3 - 864508 - - - -0.5962 - 1.915 0.392 - 442.8 1 2 0 -0.0007 11 0 0 0 5.94E+06 5.19E+06 - - - 3.6937 0.9994 221125_WJC_METTL3_EV_vs_WT_F08.04642.04642.2 0.00229 14-Dec K.R[166.11]FTDEESR[166.11].V "sp|Q9NYF8|BCLF1_HUMAN,tr|H0YF00|H0YF00_HUMAN,tr|E9PKI6|E9PKI6_HUMAN,tr|A0A1W2PQ43|A0A1W2PQ43_HUMAN,tr|E9PK91|E9PK91_HUMAN,tr|E9PK09|E9PK09_HUMAN,tr|E9PQN2|E9PQN2_HUMAN" 7 1058.4896 2.35 110800 4642 2 1058.491241 530.2521 Bcl-2-associated transcription factor 1 OS=Homo sapiens OX=9606 GN=BCLAF1 PE=1 SV=2 4.68 1430.8 - 314672 - - - 1.5721 - 2.446 0.223 - 594.6 1 2 0 0.0017 8 0 0 0 6.50E+08 2.76E+08 - - - 3.3852 0.9997 221125_WJC_METTL3_EV_vs_WT_F08.04644.04644.2 1.63E-05 18-Sep K.EK[136.11]PVC[160.03]GTTYK[136.11].V "sp|Q14444|CAPR1_HUMAN,tr|G3V153|G3V153_HUMAN" 2 1197.6035 0.91 110801 4644 2 1197.6038 599.809 Caprin-1 OS=Homo sapiens OX=9606 GN=CAPRIN1 PE=1 SV=2 8.27 1431.1 - 7.83E+06 - - - 0.2839 - 1.66 0.446 - 177 1 2 0 0.0003 10 0 0 0 1.01E+08 1.11E+08 - - - 3.7497 0.9019 221125_WJC_METTL3_EV_vs_WT_F08.04646.04646.3 0.816 Aug-36 K.DAENHEAQLK.N "sp|Q9Y266|NUDC_HUMAN,tr|A0A0A0MSS4|A0A0A0MSS4_HUMAN,tr|A0A0A0MSU9|A0A0A0MSU9_HUMAN" 3 1153.5364 1.67 110803 4646 3 1153.536894 385.5194 Nuclear migration protein nudC OS=Homo sapiens OX=9606 GN=NUDC PE=1 SV=1 4.65 1431.2 - 7.86E+06 - - - 0.4577 - 1.342 0.095 - 77.4 1 2 0 0.0005 10 0 0 0 1.48E+08 8.88E+07 - - - 0.4581 1 221125_WJC_METTL3_EV_vs_WT_F08.04650.04650.2 7.82E-05 14/18 K.DAENHEAQLK[136.11].N "sp|Q9Y266|NUDC_HUMAN,tr|A0A0A0MSS4|A0A0A0MSS4_HUMAN,tr|A0A0A0MSU9|A0A0A0MSU9_HUMAN" 3 1161.5506 1.86 110807 4650 2 1161.548865 581.7826 Nuclear migration protein nudC OS=Homo sapiens OX=9606 GN=NUDC PE=1 SV=1 4.65 1431.5 - 1.20E+06 - - - -1.4644 - 3.046 0.541 - 854.5 1 2 0 -0.0017 10 0 0 0 4.10E+07 2.21E+07 - - - 6.1453 1 221125_WJC_METTL3_EV_vs_WT_F08.04654.04654.2 1.67E-07 20-Nov K.TC[160.03]MSEETSNQK.Q "sp|Q14119|VEZF1_HUMAN,tr|J3QSH4|J3QSH4_HUMAN,tr|J9JIC7|J9JIC7_HUMAN" 3 1313.5228 1.52 110811 4654 2 1313.522683 657.7687 Vascular endothelial zinc finger 1 OS=Homo sapiens OX=9606 GN=VEZF1 PE=1 SV=2 4.53 1432 - 445352 - - - -0.0632 - 2.158 0.707 - 418.6 1 2 0 -0.0001 11 0 0 0 2.72E+06 1.79E+06 - - - 6.3437 0.9998 221125_WJC_METTL3_EV_vs_WT_F08.04655.04655.2 7.61E-06 20-Dec R.EEEEEEEASEK.G "sp|O60231|DHX16_HUMAN,tr|A0A140T947|A0A140T947_HUMAN,tr|A2AB15|A2AB15_HUMAN" 3 1336.5154 3.83 110812 4655 2 1336.512439 669.265 Pre-mRNA-splicing factor ATP-dependent RNA helicase DHX16 OS=Homo sapiens OX=9606 GN=DHX16 PE=1 SV=2 3.77 1432.1 - 394768 - - - -2.2267 - 2.457 0.513 - 619.2 1 2 0 -0.003 11 0 0 0 3.47E+06 9.07E+05 - - - 5.2609 1 221125_WJC_METTL3_EV_vs_WT_F08.04657.04657.2 1.96E-06 20-Dec K.TC[160.03]MSEETSNQK[136.11].Q "sp|Q14119|VEZF1_HUMAN,tr|J3QSH4|J3QSH4_HUMAN,tr|J9JIC7|J9JIC7_HUMAN" 3 1321.537 1.52 110814 4657 2 1321.535631 661.7758 Vascular endothelial zinc finger 1 OS=Homo sapiens OX=9606 GN=VEZF1 PE=1 SV=2 4.53 1432.4 - 281310 - - - -1.0102 - 2.331 0.647 - 476.9 1 2 0 -0.0013 11 0 0 0 2.72E+06 1.79E+06 - - - 6.1088 0.9959 221125_WJC_METTL3_EV_vs_WT_F08.04663.04663.3 2.26 Oct-40 K.LTTASQTNIK[136.11]K[136.11].S "sp|Q9UMY1|NOL7_HUMAN,tr|H7C2B1|H7C2B1_HUMAN" 2 1219.7107 1.12 110818 4663 3 1219.71061 407.5775 Nucleolar protein 7 OS=Homo sapiens OX=9606 GN=NOL7 PE=1 SV=2 10 1433.1 - 2.21E+06 - - - -0.0754 - 1.735 0.202 - 105.4 1 2 0 -0.0001 11 0 0 0 1.63E+07 1.45E+07 - - - 2.3574 0.9599 221125_WJC_METTL3_EV_vs_WT_F08.04665.04665.3 0.129 Oct-44 R.VSVAAGSEEDHK.L sp|Q9GZS1|RPA49_HUMAN 1 1227.5731 0.48 110820 4665 3 1227.573632 410.1983 DNA-directed RNA polymerase I subunit RPA49 OS=Homo sapiens OX=9606 GN=POLR1E PE=1 SV=3 4.65 1433.2 - 2.07E+06 - - - 0.3967 - 1.587 0.117 - 96.2 2 2 0 0.0005 12 0 0 0 6.55E+06 1.37E+07 - - - 0.9851 0.9573 221125_WJC_METTL3_EV_vs_WT_F08.04666.04666.2 0.008 16-Oct N.SVNSHTIGR.Y "sp|Q08188|TGM3_HUMAN,tr|A0A494C0J7|A0A494C0J7_HUMAN" 2 969.4992 7.2 110821 4666 2 969.500498 485.7569 Protein-glutamine gamma-glutamyltransferase E OS=Homo sapiens OX=9606 GN=TGM3 PE=1 SV=4 9.49 1433.3 - 1.22E+06 - - - 1.3471 - 1.681 0.344 - 369.4 1 1 0 0.0013 9 0 0 0 7.42E+06 1.03E+06 - - - 3.084 0.9998 221125_WJC_METTL3_EV_vs_WT_F08.04668.04668.2 0.0106 14-Nov K.K[136.11]LDEQYQK[136.11].Y sp|P61758|PFD3_HUMAN 1 1066.563 0.62 110823 4668 2 1066.561977 534.2888 Prefoldin subunit 3 OS=Homo sapiens OX=9606 GN=VBP1 PE=1 SV=4 6.07 1433.5 - 566713 - - - -0.9357 - 2.309 0.374 - 396.7 1 2 0 -0.001 8 0 0 0 1.67E+07 2.68E+07 - - - 4.3268 0.9945 221125_WJC_METTL3_EV_vs_WT_F08.04672.04672.2 0.916 20-Jun K.ASSTSTPEPTR[166.11].K "sp|Q8N8S7|ENAH_HUMAN,tr|A0A0U1RRM6|A0A0U1RRM6_HUMAN" 2 1142.5443 1.03 110826 4672 2 1142.544006 572.2794 Protein enabled homolog OS=Homo sapiens OX=9606 GN=ENAH PE=1 SV=2 6.05 1434 - 1.18E+06 - - - -0.2582 - 1.125 0.245 - 73.1 2 2 0 -0.0003 11 0 0 0 8.75E+07 8.53E+07 - - - 1.0346 0.9998 221125_WJC_METTL3_EV_vs_WT_F08.04674.04674.3 0.022 Oct-36 R.INVVNNHQAK[136.11].Q "sp|Q9BY77|PDIP3_HUMAN,tr|F6VRR5|F6VRR5_HUMAN,tr|F8WCX5|F8WCX5_HUMAN" 3 1143.624 0.07 110828 4674 3 1143.623556 382.2153 Polymerase delta-interacting protein 3 OS=Homo sapiens OX=9606 GN=POLDIP3 PE=1 SV=2 8.76 1434.1 - 8.40E+06 - - - -0.3926 - 2.07 0.369 - 90.2 1 2 0 -0.0004 10 0 0 0 4.73E+07 7.03E+08 - - - 4.7786 0.999 221125_WJC_METTL3_EV_vs_WT_F08.04676.04676.2 1.09E-05 14/20 R.YLEEQKTENGK.D "sp|Q9Y2W1|TR150_HUMAN,tr|A0A3B3ITZ9|A0A3B3ITZ9_HUMAN" 2 1337.6463 2.85 110830 4676 2 1337.645636 669.8304 Thyroid hormone receptor-associated protein 3 OS=Homo sapiens OX=9606 GN=THRAP3 PE=1 SV=2 4.79 1434.2 - 2.05E+06 - - - -0.5039 - 2.512 0.55 - 610.2 1 2 1 -0.0007 11 0 0 0 1.13E+08 3.96E+07 - - - 5.5948 0.9998 221125_WJC_METTL3_EV_vs_WT_F08.04677.04677.2 8.79E-06 18-Dec R.INVVNNHQAK.Q "sp|Q9BY77|PDIP3_HUMAN,tr|F6VRR5|F6VRR5_HUMAN,tr|F8WCX5|F8WCX5_HUMAN" 3 1135.6098 1.49 110831 4677 2 1135.607841 568.8122 Polymerase delta-interacting protein 3 OS=Homo sapiens OX=9606 GN=POLDIP3 PE=1 SV=2 8.76 1434.3 - 1.67E+06 - - - -1.7295 - 2.393 0.43 - 534.1 1 2 0 -0.002 10 0 0 0 2.27E+08 1.52E+08 - - - 4.6519 0.9997 221125_WJC_METTL3_EV_vs_WT_F08.04680.04680.2 0.00462 18-Nov R.INVVNNHQAK[136.11].Q "sp|Q9BY77|PDIP3_HUMAN,tr|F6VRR5|F6VRR5_HUMAN,tr|F8WCX5|F8WCX5_HUMAN" 3 1143.624 1.49 110834 4680 2 1143.623002 572.8193 Polymerase delta-interacting protein 3 OS=Homo sapiens OX=9606 GN=POLDIP3 PE=1 SV=2 8.76 1434.5 - 1.18E+06 - - - -0.877 - 2.25 0.345 - 445.9 1 2 0 -0.001 10 0 0 0 2.27E+08 1.52E+08 - - - 3.8524 0.9991 221125_WJC_METTL3_EV_vs_WT_F08.04681.04681.2 0.00998 14-Nov K.KLDEQYQK.Y sp|P61758|PFD3_HUMAN 1 1050.5346 0.63 110835 4681 2 1050.537419 526.2746 Prefoldin subunit 3 OS=Homo sapiens OX=9606 GN=VBP1 PE=1 SV=4 6.07 1434.6 - 1.13E+06 - - - 2.7072 - 2.214 0.328 - 394.3 1 2 0 0.0028 8 0 0 0 1.67E+07 2.66E+07 - - - 3.8598 0.9986 221125_WJC_METTL3_EV_vs_WT_F08.04682.04682.2 0.0156 15/20 R.YLEEQK[136.11]TENGK[136.11].D "sp|Q9Y2W1|TR150_HUMAN,tr|A0A3B3ITZ9|A0A3B3ITZ9_HUMAN" 2 1353.6747 2.83 110836 4682 2 1353.674535 677.8446 Thyroid hormone receptor-associated protein 3 OS=Homo sapiens OX=9606 GN=THRAP3 PE=1 SV=2 4.79 1434.8 - 803810 - - - -0.1293 - 2.555 0.434 - 630.8 1 2 1 -0.0002 11 0 0 0 1.12E+08 3.96E+07 - - - 4.7841 0.9993 221125_WJC_METTL3_EV_vs_WT_F08.04684.04684.2 0.0799 16-Aug K.EASEVKPPR.D "sp|O60341|KDM1A_HUMAN,tr|R4GMQ1|R4GMQ1_HUMAN" 2 1011.5349 4.37 110838 4684 2 1011.535456 506.7747 Lysine-specific histone demethylase 1A OS=Homo sapiens OX=9606 GN=KDM1A PE=1 SV=2 6.24 1435 - 454363 - - - 0.5408 - 1.616 0.314 - 199.4 1 2 0 0.0005 9 0 0 0 4.73E+06 1.08E+06 - - - 2.7486 0.9962 221125_WJC_METTL3_EV_vs_WT_F08.04691.04691.2 0.111 16-Dec R.ESDGFR[166.11]EEK[136.11].N "sp|Q9NYF8|BCLF1_HUMAN,tr|E9PKI6|E9PKI6_HUMAN,tr|A0A1W2PQ43|A0A1W2PQ43_HUMAN,tr|E9PK91|E9PK91_HUMAN,tr|E9PK09|E9PK09_HUMAN,tr|E9PQN2|E9PQN2_HUMAN" 6 1113.5057 2.26 110843 4691 2 1113.505338 557.7601 Bcl-2-associated transcription factor 1 OS=Homo sapiens OX=9606 GN=BCLAF1 PE=1 SV=2 4.41 1435.8 - 9.31E+06 - - - -0.3583 - 2.003 0.325 - 702.4 1 2 1 -0.0004 9 0 0 0 3.35E+09 1.48E+09 - - - 3.451 0.9902 221125_WJC_METTL3_EV_vs_WT_F08.04694.04694.2 0.000811 16-Oct L.NVVNNHQAK.Q "sp|Q9BY77|PDIP3_HUMAN,tr|F6VRR5|F6VRR5_HUMAN,tr|F8WCX5|F8WCX5_HUMAN" 3 1022.5257 1.56 110846 4694 2 1022.525488 512.2701 Polymerase delta-interacting protein 3 OS=Homo sapiens OX=9606 GN=POLDIP3 PE=1 SV=2 8.76 1436 - 4.65E+06 - - - -0.2474 - 1.838 0.48 - 272 1 1 0 -0.0003 9 0 0 0 8.48E+07 5.44E+07 - - - 4.3471 0.9999 221125_WJC_METTL3_EV_vs_WT_F08.04695.04695.2 5.83E-06 20-Dec K.ASVEDADTQSK.V "sp|Q13561|DCTN2_HUMAN,tr|H0YI98|H0YI98_HUMAN,tr|A8K8J9|A8K8J9_HUMAN,tr|F8W1I6|F8W1I6_HUMAN,tr|A0A7I2V4H4|A0A7I2V4H4_HUMAN,tr|A0A7I2V4Y9|A0A7I2V4Y9_HUMAN" 6 1149.515 2.7 110847 4695 2 1149.51381 575.7648 Dynactin subunit 2 OS=Homo sapiens OX=9606 GN=DCTN2 PE=1 SV=4 4.03 1436 - 4.48E+06 - - - -1.0013 - 2.289 0.57 - 738 1 2 0 -0.0012 11 0 0 0 3.86E+07 1.43E+07 - - - 5.4909 1 221125_WJC_METTL3_EV_vs_WT_F08.04697.04697.2 3.73E-06 15/24 R.GDTGGEDTAAPGR.F sp|Q9H773|DCTP1_HUMAN 1 1202.5164 0.65 110849 4697 2 1202.514466 602.2655 dCTP pyrophosphatase 1 OS=Homo sapiens OX=9606 GN=DCTPP1 PE=1 SV=1 4.03 1436.1 - 3.49E+06 - - - -1.5734 - 2.898 0.568 - 893.2 1 2 0 -0.0019 13 0 0 0 2.55E+07 3.95E+07 - - - 5.9665 0.9996 221125_WJC_METTL3_EV_vs_WT_F08.04698.04698.2 0.0435 12-Aug K.RDENWDK.E sp|Q96A49|SYAP1_HUMAN 1 961.4254 1.3 110850 4698 2 961.424299 481.72 Synapse-associated protein 1 OS=Homo sapiens OX=9606 GN=SYAP1 PE=1 SV=1 4.56 1436.2 - 2.55E+06 - - - -1.1025 - 1.607 0.389 - 359.6 1 2 0 -0.0011 7 0 0 0 1.46E+07 1.12E+07 - - - 3.4169 0.9994 221125_WJC_METTL3_EV_vs_WT_F08.04700.04700.2 0.0161 12-Aug K.R[166.11]DENWDK[136.11].E sp|Q96A49|SYAP1_HUMAN 1 979.4478 1.3 110852 4700 2 979.44672 490.7312 Synapse-associated protein 1 OS=Homo sapiens OX=9606 GN=SYAP1 PE=1 SV=1 4.56 1436.3 - 1.76E+06 - - - -1.1323 - 1.785 0.29 - 321.9 1 2 0 -0.0011 7 0 0 0 1.46E+07 1.12E+07 - - - 3.0185 0.9998 221125_WJC_METTL3_EV_vs_WT_F08.04703.04703.2 0.107 20-Nov R.QTQSASSTLQK[136.11].H "sp|O95819|M4K4_HUMAN,tr|A0A0D9SEY1|A0A0D9SEY1_HUMAN,tr|C9J840|C9J840_HUMAN,tr|E7EX83|E7EX83_HUMAN,tr|H7C360|H7C360_HUMAN,tr|A0A0D9SG62|A0A0D9SG62_HUMAN,tr|G3XAA2|G3XAA2_HUMAN,tr|E7ENQ1|E7ENQ1_HUMAN,tr|H7C0P6|H7C0P6_HUMAN,tr|G5E948|G5E948_HUMAN" 10 1185.6081 0.6 110855 4703 2 1185.606998 593.8113 Mitogen-activated protein kinase kinase kinase kinase 4 OS=Homo sapiens OX=9606 GN=MAP4K4 PE=1 SV=2 8.75 1436.7 - 992739 - - - -0.9135 - 2.119 0.428 - 498.2 1 2 0 -0.0011 11 0 0 0 3.71E+06 6.23E+06 - - - 4.2333 0.9996 221125_WJC_METTL3_EV_vs_WT_F08.04704.04704.2 0.0534 16-Oct K.TNNVNVSSR.V "sp|Q5TBB1|RNH2B_HUMAN,tr|A0A087WXR7|A0A087WXR7_HUMAN,tr|A0A2R8YCP1|A0A2R8YCP1_HUMAN,tr|A0A2R8Y6M7|A0A2R8Y6M7_HUMAN,tr|A0A2R8YEU9|A0A2R8YEU9_HUMAN,tr|A0A2R8Y687|A0A2R8Y687_HUMAN,tr|A0A2R8YEH2|A0A2R8YEH2_HUMAN,tr|A0A2R8Y459|A0A2R8Y459_HUMAN,tr|A0A2R8YCX2|A0A2R8YCX2_HUMAN,tr|A0A2R8YCJ4|A0A2R8YCJ4_HUMAN,tr|A0A2R8Y7R8|A0A2R8Y7R8_HUMAN,tr|A0A2R8Y4S2|A0A2R8Y4S2_HUMAN,tr|A0A2R8Y6Q6|A0A2R8Y6Q6_HUMAN,tr|A0A2R8YEC1|A0A2R8YEC1_HUMAN,tr|A0A2R8Y6Y1|A0A2R8Y6Y1_HUMAN,tr|A0A2R8Y761|A0A2R8Y761_HUMAN,tr|A0A087WZJ6|A0A087WZJ6_HUMAN,tr|A0A2R8YGP2|A0A2R8YGP2_HUMAN,tr|A0A2R8Y883|A0A2R8Y883_HUMAN,tr|A0A2R8Y7Q3|A0A2R8Y7Q3_HUMAN,tr|A0A2R8YE60|A0A2R8YE60_HUMAN" 21 989.489 1.14 110856 4704 2 989.487593 495.7518 Ribonuclease H2 subunit B OS=Homo sapiens OX=9606 GN=RNASEH2B PE=1 SV=1 9.41 1436.8 - 955691 - - - -1.4432 - 2.07 0.339 - 560.2 1 2 0 -0.0014 9 0 0 0 7.54E+06 6.60E+06 - - - 3.6492 0.909 221125_WJC_METTL3_EV_vs_WT_F08.04714.04714.2 0.0157 18-Dec Y.LEEQKTENGK.D "sp|Q9Y2W1|TR150_HUMAN,tr|A0A3B3ITZ9|A0A3B3ITZ9_HUMAN" 2 1174.583 2.25 110862 4714 2 1174.582386 588.2988 Thyroid hormone receptor-associated protein 3 OS=Homo sapiens OX=9606 GN=THRAP3 PE=1 SV=2 4.79 1437.8 - 3.05E+06 - - - -0.5066 - 2.279 0.435 - 528.1 1 1 1 -0.0006 10 0 0 0 1.89E+07 8.39E+06 - - - 4.553 0.9046 221125_WJC_METTL3_EV_vs_WT_F08.04715.04715.2 0.0696 14-Oct N.VVNNHQAK[136.11].Q "sp|Q9BY77|PDIP3_HUMAN,tr|F6VRR5|F6VRR5_HUMAN,tr|F8WCX5|F8WCX5_HUMAN" 3 916.497 1.57 110863 4715 2 916.494684 459.2558 Polymerase delta-interacting protein 3 OS=Homo sapiens OX=9606 GN=POLDIP3 PE=1 SV=2 8.73 1437.8 - 2.99E+06 - - - -2.5423 - 1.603 0.334 - 262.1 1 1 0 -0.0023 8 0 0 0 3.22E+07 2.04E+07 - - - 2.9304 0.958 221125_WJC_METTL3_EV_vs_WT_F08.04716.04716.3 1.2 Oct-48 K.VAPAPARPSGPSK.A "sp|P48444|COPD_HUMAN,tr|B0YIW6|B0YIW6_HUMAN" 2 1233.683 0.67 110864 4716 3 1233.683426 412.2349 Coatomer subunit delta OS=Homo sapiens OX=9606 GN=ARCN1 PE=1 SV=1 11 1437.9 - 2.58E+06 - - - 0.3696 - 1.692 0.089 - 113.7 1 2 0 0.0005 13 0 0 0 5.56E+07 8.34E+07 - - - 0.958 0.9998 221125_WJC_METTL3_EV_vs_WT_F08.04718.04718.2 2.31E-05 20-Dec K.ASVEDADTQSK[136.11].V "sp|Q13561|DCTN2_HUMAN,tr|H0YI98|H0YI98_HUMAN,tr|A8K8J9|A8K8J9_HUMAN,tr|F8W1I6|F8W1I6_HUMAN,tr|A0A7I2V4H4|A0A7I2V4H4_HUMAN,tr|A0A7I2V4Y9|A0A7I2V4Y9_HUMAN" 6 1157.5292 2.77 110866 4718 2 1157.5271 579.7719 Dynactin subunit 2 OS=Homo sapiens OX=9606 GN=DCTN2 PE=1 SV=4 4.03 1438.1 - 1.69E+06 - - - -1.7805 - 2.132 0.511 - 428.1 1 2 0 -0.0021 11 0 0 0 4.04E+07 1.46E+07 - - - 4.8626 0.9886 221125_WJC_METTL3_EV_vs_WT_F08.04721.04721.2 0.0673 18-Aug R.TAAPSVR[166.11]PEK[136.11].R "sp|Q14137|BOP1_HUMAN,tr|A0A075B729|A0A075B729_HUMAN" 2 1072.5996 0.22 110869 4721 2 1072.596103 537.3071 Ribosome biogenesis protein BOP1 OS=Homo sapiens OX=9606 GN=BOP1 PE=1 SV=2 8.41 1438.5 - 370595 - - - -3.2398 - 1.463 0.221 - 224.4 1 2 0 -0.0035 10 0 0 0 2.67E+06 1.24E+07 - - - 1.7343 0.9981 221125_WJC_METTL3_EV_vs_WT_F08.04729.04729.2 0.00192 18-Dec R.VRYDSSNQVK.G "sp|O95983|MBD3_HUMAN,tr|A0A087X1H1|A0A087X1H1_HUMAN,tr|K7EIE8|K7EIE8_HUMAN,tr|A0A087WT34|A0A087WT34_HUMAN,tr|A0A0A0MTS6|A0A0A0MTS6_HUMAN,tr|A0A087WZ12|A0A087WZ12_HUMAN" 6 1194.5993 1.1 110874 4729 2 1194.598802 598.3069 Methyl-CpG-binding domain protein 3 OS=Homo sapiens OX=9606 GN=MBD3 PE=1 SV=1 8.56 1439.1 - 3.71E+06 - - - -0.4169 - 2.152 0.43 - 527 1 2 1 -0.0005 10 0 0 0 3.26E+07 2.95E+07 - - - 4.3561 0.9933 221125_WJC_METTL3_EV_vs_WT_F08.04731.04731.2 0.27 16-Nov R.ESDGFR[166.11]EEK.N "sp|Q9NYF8|BCLF1_HUMAN,tr|E9PKI6|E9PKI6_HUMAN,tr|A0A1W2PQ43|A0A1W2PQ43_HUMAN,tr|E9PK91|E9PK91_HUMAN,tr|E9PK09|E9PK09_HUMAN,tr|E9PQN2|E9PQN2_HUMAN" 6 1105.4915 - 110876 4731 2 1105.491037 553.753 Bcl-2-associated transcription factor 1 OS=Homo sapiens OX=9606 GN=BCLAF1 PE=1 SV=2 4.41 1439.4 - 1.92E+06 - - - -0.4523 - 1.756 0.296 - 451.4 1 2 1 -0.0005 9 0 0 0 - - - - - 2.856 0.9999 221125_WJC_METTL3_EV_vs_WT_F08.04732.04732.2 2.32E-05 14/18 K.HSEVQQANLK[136.11].A "sp|P35606|COPB2_HUMAN,tr|H0Y938|H0Y938_HUMAN,tr|A0A7I2V258|A0A7I2V258_HUMAN,tr|H0YAC7|H0YAC7_HUMAN" 4 1160.6029 0.42 110877 4732 2 1160.601397 581.3087 Coatomer subunit beta' OS=Homo sapiens OX=9606 GN=COPB2 PE=1 SV=2 6.75 1439.5 - 1.39E+06 - - - -1.326 - 2.958 0.468 - 536.7 1 2 0 -0.0015 10 0 0 0 4.27E+06 1.02E+07 - - - 5.5244 0.9976 221125_WJC_METTL3_EV_vs_WT_F08.04742.04742.3 0.385 Nov-48 K.VAPAPAR[166.11]PSGPSK[136.11].A "sp|P48444|COPD_HUMAN,tr|B0YIW6|B0YIW6_HUMAN" 2 1251.7054 0.69 110885 4742 3 1251.703345 418.2424 Coatomer subunit delta OS=Homo sapiens OX=9606 GN=ARCN1 PE=1 SV=1 11 1440.5 - 6.98E+06 - - - -1.6737 - 1.891 0.241 - 130.7 1 2 0 -0.0021 13 0 0 0 5.76E+07 8.38E+07 - - - 2.9537 0.9996 221125_WJC_METTL3_EV_vs_WT_F08.04743.04743.2 9.84E-07 16-Oct R.TGHWLNHGK[136.11].E sp|Q86U44|MTA70_HUMAN 1 1056.5345 0.07 110886 4743 2 1056.535329 529.2745 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 8.47 1440.6 - 6.84E+06 - - - 0.8206 - 1.906 0.359 - 310.8 1 2 0 0.0009 9 0 0 0 1.44E+07 2.17E+08 - - - 3.5583 0.999 221125_WJC_METTL3_EV_vs_WT_F08.04751.04751.2 0.000343 18-Nov R.LQGEIAHVKK.Q sp|P35908|K22E_HUMAN 1 1121.6557 999 110892 4751 2 1121.653093 561.8351 "Keratin, type II cytoskeletal 2 epidermal OS=Homo sapiens OX=9606 GN=KRT2 PE=1 SV=2" 8.6 1441.5 - 4.94E+06 - - - -2.318 - 1.781 0.37 - 269 1 2 0 -0.0026 10 0 0 0 4.82E+07 0.00E+00 - - - 3.3841 0.9598 221125_WJC_METTL3_EV_vs_WT_F08.04755.04755.2 0.00328 16-Sep L.QGEIAHVKK.Q sp|P35908|K22E_HUMAN 1 1008.5716 999 110896 4755 2 1008.571161 505.2931 "Keratin, type II cytoskeletal 2 epidermal OS=Homo sapiens OX=9606 GN=KRT2 PE=1 SV=2" 8.6 1441.7 - 1.63E+06 - - - -0.464 - 1.735 0.282 - 259.6 1 1 0 -0.0005 9 0 0 0 1.76E+07 0.00E+00 - - - 2.7178 1 221125_WJC_METTL3_EV_vs_WT_F08.04765.04765.3 5.45E-07 13/44 K.C[160.03]LAC[160.03]ESAK[136.11]PGTK[136.11].S sp|P49790|NU153_HUMAN 1 1336.645 0.84 110904 4765 3 1336.642647 446.5556 Nuclear pore complex protein Nup153 OS=Homo sapiens OX=9606 GN=NUP153 PE=1 SV=2 8.05 1442.8 - 5.89E+06 - - - -1.7656 - 2.583 0.6 - 250.9 1 2 0 -0.0024 12 0 0 0 1.85E+08 2.21E+08 - - - 7.8591 0.9999 221125_WJC_METTL3_EV_vs_WT_F08.04767.04767.2 0.000802 13/22 R.GSGSGQSPSYGR.H sp|Q86YZ3|HORN_HUMAN 1 1138.5003 6.2 110906 4767 2 1138.5014 570.2574 Hornerin OS=Homo sapiens OX=9606 GN=HRNR PE=1 SV=2 8.75 1442.8 - 3.87E+06 - - - 0.9539 - 2.794 0.515 - 554.9 1 2 0 0.0011 12 0 0 0 7.25E+07 1.17E+07 - - - 5.5479 0.9845 221125_WJC_METTL3_EV_vs_WT_F08.04768.04768.2 0.000728 14-Oct T.GHWLNHGK[136.11].E sp|Q86U44|MTA70_HUMAN 1 955.4868 0.05 110907 4768 2 955.485222 478.7507 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 8.76 1443 - 2.31E+06 - - - -1.6337 - 1.863 0.477 - 410.9 1 1 0 -0.0016 8 0 0 0 1.75E+06 3.68E+07 - - - 4.4401 0.9996 221125_WJC_METTL3_EV_vs_WT_F08.04769.04769.2 3.83E-06 20-Nov R.SSGNSPTPVSR.W "sp|O95429|BAG4_HUMAN,tr|H0YBT1|H0YBT1_HUMAN" 2 1087.5258 0.46 110908 4769 2 1087.52459 544.7702 BAG family molecular chaperone regulator 4 OS=Homo sapiens OX=9606 GN=BAG4 PE=1 SV=1 9.47 1443.1 - 1.52E+06 - - - -1.1135 - 1.88 0.365 - 225.1 1 2 0 -0.0012 11 0 0 0 1.59E+07 3.42E+07 - - - 3.4442 0.999 221125_WJC_METTL3_EV_vs_WT_F08.04775.04775.2 0.631 16-Oct R.FQESEER[166.11]PK[136.11].L sp|P34932|HSP74_HUMAN 1 1166.5687 0.1 110912 4775 2 1166.566698 584.2916 Heat shock 70 kDa protein 4 OS=Homo sapiens OX=9606 GN=HSPA4 PE=1 SV=4 4.79 1443.9 - 3.89E+06 - - - -1.6921 - 1.917 0.269 - 304.8 1 2 0 -0.002 9 0 0 0 7.99E+06 8.40E+07 - - - 2.9099 0.9884 221125_WJC_METTL3_EV_vs_WT_F08.04779.04779.2 0.792 14-Aug R.RILPKPTR.K "sp|P62081|RS7_HUMAN,tr|B5MCP9|B5MCP9_HUMAN,tr|A0A2R8Y623|A0A2R8Y623_HUMAN" 3 979.6291 0.83 110916 4779 2 979.627296 490.8218 40S ribosomal protein S7 OS=Homo sapiens OX=9606 GN=RPS7 PE=1 SV=1 12.01 1444.2 - 1.06E+06 - - - -1.8252 - 1.357 0.135 - 111.2 1 2 0 -0.0018 8 0 0 0 8.62E+06 1.04E+07 - - - 0.9582 0.9998 221125_WJC_METTL3_EV_vs_WT_F08.04780.04780.2 0.00206 13/22 K.C[160.03]LAC[160.03]ESAKPGTK.S sp|P49790|NU153_HUMAN 1 1320.6166 0.23 110917 4780 2 1320.615375 661.3156 Nuclear pore complex protein Nup153 OS=Homo sapiens OX=9606 GN=NUP153 PE=1 SV=2 8.05 1444.3 - 958354 - - - -0.9329 - 2.18 0.41 - 412.9 1 2 0 -0.0012 12 0 0 0 1.17E+07 5.15E+07 - - - 4.1194 0.9827 221125_WJC_METTL3_EV_vs_WT_F08.04782.04782.2 0.0228 16-Oct R.TGHWLNHGK.E sp|Q86U44|MTA70_HUMAN 1 1048.5203 0.03 110919 4782 2 1048.515995 525.2674 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 8.47 1444.6 - 562193 - - - -4.0695 - 1.35 0.267 - 254.6 1 2 0 -0.0043 9 0 0 0 5.50E+06 1.69E+08 - - - 1.8799 0.9519 221125_WJC_METTL3_EV_vs_WT_F08.04784.04784.2 0.179 18-Jul R.YK[136.11]DQTGGYTR[166.11].M "sp|Q9NRX2|RM17_HUMAN,tr|E9PKV2|E9PKV2_HUMAN" 2 1205.5796 26.17 110921 4784 2 1205.583539 603.7971 "39S ribosomal protein L17, mitochondrial OS=Homo sapiens OX=9606 GN=MRPL17 PE=1 SV=1" 8.5 1444.8 - 351150 - - - 3.2914 - 1.675 0.284 - 118.9 1 2 1 0.004 10 0 0 0 6.39E+07 2.44E+06 - - - 2.5772 1 221125_WJC_METTL3_EV_vs_WT_F08.04787.04787.3 0.00152 Dec-36 K.TSEDADELHK.L sp|Q9UKX7|NUP50_HUMAN 1 1143.5044 1.23 110922 4787 3 1143.503864 382.1754 Nuclear pore complex protein Nup50 OS=Homo sapiens OX=9606 GN=NUP50 PE=1 SV=2 4.31 1445.2 - 1.17E+07 - - - -0.4661 - 2.636 0.407 - 300.3 1 2 0 -0.0005 10 0 0 0 8.29E+07 6.73E+07 - - - 5.9082 1 221125_WJC_METTL3_EV_vs_WT_F08.04788.04788.3 0.0191 14/36 K.TSEDADELHK[136.11].L sp|Q9UKX7|NUP50_HUMAN 1 1151.5186 1.28 110923 4788 3 1151.517257 384.8468 Nuclear pore complex protein Nup50 OS=Homo sapiens OX=9606 GN=NUP50 PE=1 SV=2 4.31 1445.3 - 8.03E+06 - - - -1.1637 - 2.674 0.484 - 369.1 1 2 0 -0.0013 10 0 0 0 8.35E+07 6.52E+07 - - - 6.8082 0.9916 221125_WJC_METTL3_EV_vs_WT_F08.04790.04790.3 0.0232 Jul-36 R.YK[136.11]DQTGGYTR[166.11].M "sp|Q9NRX2|RM17_HUMAN,tr|E9PKV2|E9PKV2_HUMAN" 2 1205.5796 9.25 110925 4790 3 1205.577949 402.8671 "39S ribosomal protein L17, mitochondrial OS=Homo sapiens OX=9606 GN=MRPL17 PE=1 SV=1" 8.5 1445.4 - 2.05E+06 - - - -1.3454 - 1.536 0.288 - 48.6 1 2 1 -0.0016 10 0 0 0 1.62E+08 1.75E+07 - - - 3.0039 0.9999 221125_WJC_METTL3_EV_vs_WT_F08.04791.04791.2 0.000122 18-Nov K.TSEDADELHK.L sp|Q9UKX7|NUP50_HUMAN 1 1143.5044 2.89 110926 4791 2 1143.502707 572.7595 Nuclear pore complex protein Nup50 OS=Homo sapiens OX=9606 GN=NUP50 PE=1 SV=2 4.31 1445.4 - 1.83E+06 - - - -1.4779 - 2.414 0.546 - 618.3 1 2 0 -0.0017 10 0 0 0 4.36E+07 1.51E+07 - - - 5.5332 0.9999 221125_WJC_METTL3_EV_vs_WT_F08.04794.04794.2 9.76E-08 14/22 K.C[160.03]LAC[160.03]ESAK[136.11]PGTK[136.11].S sp|P49790|NU153_HUMAN 1 1336.645 0.18 110929 4794 2 1336.644733 669.3298 Nuclear pore complex protein Nup153 OS=Homo sapiens OX=9606 GN=NUP153 PE=1 SV=2 8.05 1445.8 - 738150 - - - -0.205 - 2.259 0.581 - 495.3 1 2 0 -0.0003 12 0 0 0 1.17E+07 6.66E+07 - - - 5.4764 0.9722 221125_WJC_METTL3_EV_vs_WT_F08.04795.04795.2 0.0045 16-Oct T.SEDADELHK.L sp|Q9UKX7|NUP50_HUMAN 1 1042.4567 1.95 110930 4795 2 1042.456182 522.2356 Nuclear pore complex protein Nup50 OS=Homo sapiens OX=9606 GN=NUP50 PE=1 SV=2 4.31 1445.9 - 679678 - - - -0.5142 - 1.826 0.314 - 396.5 1 1 0 -0.0005 9 0 0 0 4.74E+06 2.44E+06 - - - 3.102 0.9954 221125_WJC_METTL3_EV_vs_WT_F08.04796.04796.2 0.00179 18-Sep R.ASDK[136.11]DITVSK[136.11].N sp|P49790|NU153_HUMAN 1 1078.5841 1.17 110931 4796 2 1078.582547 540.2993 Nuclear pore complex protein Nup153 OS=Homo sapiens OX=9606 GN=NUP153 PE=1 SV=2 6 1446.1 - 409652 - - - -1.4436 - 2.04 0.359 - 236.3 1 2 1 -0.0016 10 0 0 0 1.06E+07 9.08E+06 - - - 3.6821 1 221125_WJC_METTL3_EV_vs_WT_F08.04804.04804.2 3.07E-11 16/24 K.AGPKADGEEDEVK.A "sp|Q15020|SART3_HUMAN,tr|A0A494C0L2|A0A494C0L2_HUMAN,tr|F8W667|F8W667_HUMAN,tr|A0A499FI31|A0A499FI31_HUMAN" 4 1343.6205 6.5 110938 4804 2 1343.62134 672.8175 Squamous cell carcinoma antigen recognized by T-cells 3 OS=Homo sapiens OX=9606 GN=SART3 PE=1 SV=1 4.18 1446.9 - 391554 - - - 0.6334 - 2.976 0.587 - 759.4 1 2 1 0.0009 13 0 0 0 2.85E+06 4.38E+05 - - - 6.1753 0.9408 221125_WJC_METTL3_EV_vs_WT_F08.04810.04810.2 0.0379 14-Jul R.EK[136.11]DQADFR[166.11].G sp|Q96I24|FUBP3_HUMAN 1 1025.4897 0.27 110942 4810 2 1025.487103 513.7521 Far upstream element-binding protein 3 OS=Homo sapiens OX=9606 GN=FUBP3 PE=1 SV=2 4.56 1447.7 - 2.81E+06 - - - -2.5256 - 1.305 0.277 - 211.8 1 2 1 -0.0026 8 0 0 0 3.95E+08 1.47E+09 - - - 1.889 0.9936 221125_WJC_METTL3_EV_vs_WT_F08.04812.04812.2 0.0127 14-Aug R.EKDQADFR.G sp|Q96I24|FUBP3_HUMAN 1 1007.4672 0.27 110944 4812 2 1007.466893 504.7409 Far upstream element-binding protein 3 OS=Homo sapiens OX=9606 GN=FUBP3 PE=1 SV=2 4.56 1447.9 - 2.39E+06 - - - -0.3276 - 1.456 0.368 - 276.1 1 2 1 -0.0003 8 0 0 0 3.95E+08 1.46E+09 - - - 2.892 0.9999 221125_WJC_METTL3_EV_vs_WT_F08.04813.04813.2 3.38E-07 13/24 R.GGSGGGGEGIQDR[166.11].E "sp|O43823|AKAP8_HUMAN,tr|A0A7P0TBC8|A0A7P0TBC8_HUMAN,tr|A0A7P0T893|A0A7P0T893_HUMAN,tr|M0QX51|M0QX51_HUMAN" 4 1155.5144 1.27 110945 4813 2 1155.514736 578.7645 A-kinase anchor protein 8 OS=Homo sapiens OX=9606 GN=AKAP8 PE=1 SV=1 4.37 1448 - 1.20E+06 - - - 0.2925 - 2.793 0.466 - 682.2 1 2 0 0.0003 13 0 0 0 3.36E+07 2.65E+07 - - - 5.1189 0.9998 221125_WJC_METTL3_EV_vs_WT_F08.04815.04815.2 0.000394 18-Aug R.TSSSSSFSDK.K sp|Q03111|ENL_HUMAN 1 1031.4407 1.07 110947 4815 2 1031.44062 516.7276 Protein ENL OS=Homo sapiens OX=9606 GN=MLLT1 PE=1 SV=2 5.5 1448.3 - 385550 - - - -0.1105 - 1.817 0.509 - 244.6 1 2 0 -0.0001 10 0 0 0 6.95E+06 6.52E+06 - - - 4.4674 0.9997 221125_WJC_METTL3_EV_vs_WT_F08.04825.04825.2 1.37E-06 13/22 R.STDSEVSQSPAK[136.11].N "sp|O75175|CNOT3_HUMAN,tr|B7Z6J7|B7Z6J7_HUMAN,tr|A0A2H2FJL5|A0A2H2FJL5_HUMAN,tr|H7C3F5|H7C3F5_HUMAN,tr|A0A0G2JNJ7|A0A0G2JNJ7_HUMAN,tr|H7C148|H7C148_HUMAN" 6 1242.5819 2.89 110956 4825 2 1242.578566 622.2982 CCR4-NOT transcription complex subunit 3 OS=Homo sapiens OX=9606 GN=CNOT3 PE=1 SV=1 4.37 1449.4 - 196764 - - - -2.7032 - 2.5 0.546 - 608.2 1 2 0 -0.0034 12 0 0 0 2.71E+07 9.38E+06 - - - 5.4836 0.9422 221125_WJC_METTL3_EV_vs_WT_F08.04829.04829.3 0.228 Sep-36 K.QK[136.11]ELAETEPK[136.11].F sp|Q9UQE7|SMC3_HUMAN 1 1187.6369 0.89 110958 4829 3 1187.63674 396.8862 Structural maintenance of chromosomes protein 3 OS=Homo sapiens OX=9606 GN=SMC3 PE=1 SV=2 4.79 1449.9 - 5.62E+06 - - - -0.1078 - 1.606 0.154 - 104.5 1 2 1 -0.0001 10 0 0 0 6.17E+07 6.91E+07 - - - 1.6405 1 221125_WJC_METTL3_EV_vs_WT_F08.04830.04830.3 3.10E-05 14/40 K.K[136.11]ETEGDVTSVK[136.11].D sp|P50990|TCPQ_HUMAN 1 1207.6267 0.96 110959 4830 3 1207.628141 403.5495 T-complex protein 1 subunit theta OS=Homo sapiens OX=9606 GN=CCT8 PE=1 SV=4 4.68 1450 - 3.48E+06 - - - 1.1957 - 2.53 0.445 - 452.1 1 2 0 0.0014 11 0 0 0 3.26E+07 3.41E+07 - - - 6.1378 0.978 221125_WJC_METTL3_EV_vs_WT_F08.04832.04832.3 0.327 Oct-32 R.FQESEERPK.L sp|P34932|HSP74_HUMAN 1 1148.5462 0.09 110961 4832 3 1148.547522 383.856 Heat shock 70 kDa protein 4 OS=Homo sapiens OX=9606 GN=HSPA4 PE=1 SV=4 4.79 1450.1 - 2.32E+06 - - - 1.1493 - 1.479 0.154 - 95.1 1 2 0 0.0013 9 0 0 0 4.09E+07 4.34E+08 - - - 1.4361 0.9998 221125_WJC_METTL3_EV_vs_WT_F08.04833.04833.2 0.00417 15/16 K.K[136.11]LNVTEQEK[136.11].L "sp|P06733|ENOA_HUMAN,tr|A0A2R8Y6G6|A0A2R8Y6G6_HUMAN,tr|K7EM90|K7EM90_HUMAN,tr|A0A2R8Y879|A0A2R8Y879_HUMAN,tr|A0A2R8Y6I8|A0A2R8Y6I8_HUMAN,tr|A0A2R8YEM5|A0A2R8YEM5_HUMAN" 6 1103.6157 1.57 110962 4833 2 1103.615836 552.8151 Alpha-enolase OS=Homo sapiens OX=9606 GN=ENO1 PE=1 SV=2 6.14 1450.1 - 2.24E+06 - - - 0.0879 - 2.736 0.335 - 786.1 1 2 0 0.0001 9 0 0 0 4.14E+08 2.64E+08 - - - 4.4271 1 221125_WJC_METTL3_EV_vs_WT_F08.04834.04834.3 0.000467 17/52 K.VAPAQPSEEGPGRK.D "sp|P23588|IF4B_HUMAN,tr|E7EX17|E7EX17_HUMAN" 2 1421.7263 3.28 110963 4834 3 1421.726917 474.916 Eukaryotic translation initiation factor 4B OS=Homo sapiens OX=9606 GN=EIF4B PE=1 SV=2 6.11 1450.2 - 1.70E+06 - - - 0.4396 - 2.705 0.489 - 458.5 1 2 0 0.0006 14 0 0 0 2.50E+07 7.63E+06 - - - 6.6362 0.9977 221125_WJC_METTL3_EV_vs_WT_F08.04837.04837.2 0.00394 18-Oct K.QK[136.11]ELAETEPK[136.11].F sp|Q9UQE7|SMC3_HUMAN 1 1187.6369 0.88 110966 4837 2 1187.637459 594.8257 Structural maintenance of chromosomes protein 3 OS=Homo sapiens OX=9606 GN=SMC3 PE=1 SV=2 4.79 1450.5 - 929877 - - - 0.4976 - 1.855 0.463 - 325.3 1 2 1 0.0006 10 0 0 0 1.30E+07 1.48E+07 - - - 4.1852 0.9998 221125_WJC_METTL3_EV_vs_WT_F08.04843.04843.2 0.00113 14-Nov R.R[166.11]STDFTSR[166.11].D sp|O43143|DHX15_HUMAN 1 988.4841 1.98 110970 4843 2 988.483581 495.2493 Pre-mRNA-splicing factor ATP-dependent RNA helicase DHX15 OS=Homo sapiens OX=9606 GN=DHX15 PE=1 SV=2 9.6 1451.3 - 1.88E+06 - - - -0.523 - 2.328 0.398 - 315.1 1 2 0 -0.0005 8 0 0 0 6.26E+07 3.16E+07 - - - 4.529 0.9907 221125_WJC_METTL3_EV_vs_WT_F08.04847.04847.2 0.00141 18-Oct K.QKELAETEPK.F sp|Q9UQE7|SMC3_HUMAN 1 1171.6085 0.88 110974 4847 2 1171.611231 586.8115 Structural maintenance of chromosomes protein 3 OS=Homo sapiens OX=9606 GN=SMC3 PE=1 SV=2 4.79 1451.6 - 1.21E+06 - - - 2.3583 - 1.928 0.374 - 337.2 1 2 1 0.0028 10 0 0 0 1.30E+07 1.48E+07 - - - 3.6349 0.9983 221125_WJC_METTL3_EV_vs_WT_F08.04849.04849.3 0.0514 Oct-36 R.ILQEHEQIKK.K sp|Q14152|EIF3A_HUMAN 1 1264.7139 1.32 110976 4849 3 1264.71302 422.5786 Eukaryotic translation initiation factor 3 subunit A OS=Homo sapiens OX=9606 GN=EIF3A PE=1 SV=1 6.76 1451.7 - 573011 - - - -0.7243 - 1.805 0.239 - 123.2 1 2 0 -0.0009 10 0 0 0 1.67E+07 1.26E+07 - - - 2.9291 1 221125_WJC_METTL3_EV_vs_WT_F08.04853.04853.2 2.49E-06 15/26 K.LGQGVNHAADQAGK.E sp|Q6UWP8|SBSN_HUMAN 1 1364.6797 999 110980 4853 2 1364.680523 683.3471 Suprabasin OS=Homo sapiens OX=9606 GN=SBSN PE=1 SV=2 6.74 1452.3 - 175384 - - - 0.6207 - 3.132 0.542 - 719.9 1 2 0 0.0008 14 0 0 0 1.44E+07 0.00E+00 - - - 5.9089 0.9992 221125_WJC_METTL3_EV_vs_WT_F08.04856.04856.3 0.00117 Sep-36 K.QKELAETEPK.F sp|Q9UQE7|SMC3_HUMAN 1 1171.6085 0.89 110981 4856 3 1171.607757 391.5434 Structural maintenance of chromosomes protein 3 OS=Homo sapiens OX=9606 GN=SMC3 PE=1 SV=2 4.79 1452.7 - 6.11E+06 - - - -0.6069 - 1.903 0.386 - 108.2 1 2 1 -0.0007 10 0 0 0 6.17E+07 6.91E+07 - - - 4.7224 1 221125_WJC_METTL3_EV_vs_WT_F08.04857.04857.3 2.72E-05 16/52 K.LGQGVNHAADQAGK.E sp|Q6UWP8|SBSN_HUMAN 1 1364.6797 146.29 110982 4857 3 1364.678916 455.9005 Suprabasin OS=Homo sapiens OX=9606 GN=SBSN PE=1 SV=2 6.74 1452.7 - 4.48E+06 - - - -0.5569 - 3.357 0.554 - 405.7 1 2 0 -0.0008 14 0 0 0 8.49E+07 5.80E+05 - - - 7.9347 0.8182 221125_WJC_METTL3_EV_vs_WT_F08.04861.04861.2 0.0939 14-Jun K.EQNYC[160.03]ESR[166.11].Y "sp|Q7L5D6|GET4_HUMAN,tr|C9JPA8|C9JPA8_HUMAN,tr|C9JY46|C9JY46_HUMAN" 3 1094.4326 0.35 110985 4861 2 1094.426787 548.2236 Golgi to ER traffic protein 4 homolog OS=Homo sapiens OX=9606 GN=GET4 PE=1 SV=1 4.53 1452.9 - 1.47E+06 - - - -5.3507 - 0.949 0.246 - 114.7 1 2 0 -0.0059 8 0 0 0 9.63E+06 2.75E+07 - - - 0.6982 0.999 221125_WJC_METTL3_EV_vs_WT_F08.04863.04863.2 0.00223 18-Jun K.HC[160.03]FTSNEAAR[166.11].D "sp|Q9BV44|THUM3_HUMAN,tr|H7C0R6|H7C0R6_HUMAN,tr|H7C3J3|H7C3J3_HUMAN" 3 1201.5174 0.78 110987 4863 2 1201.515611 601.766 THUMP domain-containing protein 3 OS=Homo sapiens OX=9606 GN=THUMPD3 PE=1 SV=1 6.74 1453.1 - 256287 - - - -1.4681 - 1.323 0.403 - 81.9 1 2 0 -0.0018 10 0 0 0 1.49E+06 1.91E+06 - - - 2.7983 0.9993 221125_WJC_METTL3_EV_vs_WT_F08.04868.04868.3 0.000134 Nov-44 R.EGTAPAKVEEAR.A sp|O15119|TBX3_HUMAN 1 1256.6361 0.99 110990 4868 3 1256.634024 419.886 T-box transcription factor TBX3 OS=Homo sapiens OX=9606 GN=TBX3 PE=1 SV=4 4.79 1453.6 - 1.27E+06 - - - -1.6361 - 2.133 0.408 - 184.9 1 2 1 -0.0021 12 0 0 0 7.36E+07 7.41E+07 - - - 5.188 0.9998 221125_WJC_METTL3_EV_vs_WT_F08.04872.04872.3 8.05E-06 14/44 R.EGTAPAK[136.11]VEEAR[166.11].A sp|O15119|TBX3_HUMAN 1 1274.6586 0.99 110992 4872 3 1274.657198 425.8935 T-box transcription factor TBX3 OS=Homo sapiens OX=9606 GN=TBX3 PE=1 SV=4 4.79 1454.2 - 3.18E+06 - - - -1.0607 - 2.362 0.493 - 383.6 1 2 1 -0.0014 12 0 0 0 7.36E+07 7.41E+07 - - - 6.4185 1 221125_WJC_METTL3_EV_vs_WT_F08.04875.04875.2 1.69E-05 15/24 L.GQGVNHAADQAGK.E sp|Q6UWP8|SBSN_HUMAN 1 1251.5956 999 110994 4875 2 1251.59432 626.8051 Suprabasin OS=Homo sapiens OX=9606 GN=SBSN PE=1 SV=2 6.74 1454.5 - 251664 - - - -1.0323 - 2.768 0.573 - 906.6 1 1 0 -0.0013 13 0 0 0 1.73E+06 0.00E+00 - - - 5.8858 0.9963 221125_WJC_METTL3_EV_vs_WT_F08.04881.04881.2 2.99E-05 22-Nov R.EGTAPAKVEEAR.A sp|O15119|TBX3_HUMAN 1 1256.6361 0.91 110997 4881 2 1256.633629 629.3253 T-box transcription factor TBX3 OS=Homo sapiens OX=9606 GN=TBX3 PE=1 SV=4 4.79 1455.3 - 532209 - - - -1.9504 - 1.987 0.484 - 347.2 1 2 1 -0.0024 12 0 0 0 9.74E+06 1.07E+07 - - - 4.4217 0.9998 221125_WJC_METTL3_EV_vs_WT_F08.04882.04882.2 0.0291 22-Sep R.LQDEDASSTQQR.R "sp|Q15032|R3HD1_HUMAN,tr|H7C1X4|H7C1X4_HUMAN,tr|A0A804HIA8|A0A804HIA8_HUMAN,tr|H7C207|H7C207_HUMAN" 4 1376.6168 1.3 110998 4882 2 1376.618181 689.3157 R3H domain-containing protein 1 OS=Homo sapiens OX=9606 GN=R3HDM1 PE=1 SV=3 4.03 1455.4 - 294260 - - - 1.0025 - 2.153 0.508 - 274 1 2 0 0.0014 12 0 0 0 3.93E+06 3.02E+06 - - - 4.8104 0.9986 221125_WJC_METTL3_EV_vs_WT_F08.04898.04898.2 2.04E-06 22-Dec R.EGTAPAK[136.11]VEEAR[166.11].A sp|O15119|TBX3_HUMAN 1 1274.6586 0.91 111010 4898 2 1274.656965 638.3366 T-box transcription factor TBX3 OS=Homo sapiens OX=9606 GN=TBX3 PE=1 SV=4 4.79 1457.1 - 792146 - - - -1.2435 - 2.375 0.56 - 544.5 1 2 1 -0.0016 12 0 0 0 9.74E+06 1.07E+07 - - - 5.4526 0.9999 221125_WJC_METTL3_EV_vs_WT_F08.04903.04903.2 5.47E-05 22-Nov K.NEPQNATGAPGR.N sp|P51148|RAB5C_HUMAN 1 1210.5691 1.34 111014 4903 2 1210.569996 606.2918 Ras-related protein Rab-5C OS=Homo sapiens OX=9606 GN=RAB5C PE=1 SV=2 6 1457.7 - 1.47E+06 - - - 0.7707 - 2.221 0.604 - 521.3 1 2 0 0.0009 12 0 0 0 5.47E+07 4.08E+07 - - - 5.6014 0.9938 221125_WJC_METTL3_EV_vs_WT_F08.04904.04904.2 0.011 16-Oct R.SATR[166.11]EPPYR[166.11].V "sp|P43243|MATR3_HUMAN,tr|A8MXP9|A8MXP9_HUMAN,tr|D6R991|D6R991_HUMAN,tr|A0A0R4J2E8|A0A0R4J2E8_HUMAN,tr|D6REM6|D6REM6_HUMAN" 5 1095.5576 1.64 111015 4904 2 1095.557561 548.7861 Matrin-3 OS=Homo sapiens OX=9606 GN=MATR3 PE=1 SV=2 8.46 1457.7 - 2.07E+06 - - - -0.0329 - 1.79 0.297 - 219.1 1 2 1 0 9 0 0 0 3.75E+07 2.29E+07 - - - 2.919 0.999 221125_WJC_METTL3_EV_vs_WT_F08.04907.04907.2 6.27E-08 13/24 K.TEESPASDEAGEK[136.11].E "sp|P05114|HMGN1_HUMAN,tr|A6NEL0|A6NEL0_HUMAN,tr|A6NL93|A6NL93_HUMAN" 3 1356.5772 1.64 111018 4907 2 1356.571837 679.2959 Non-histone chromosomal protein HMG-14 OS=Homo sapiens OX=9606 GN=HMGN1 PE=1 SV=3 3.91 1458.1 - 315170 - - - -3.9784 - 2.677 0.48 - 523.6 1 2 0 -0.0054 13 0 0 0 1.90E+07 1.16E+07 - - - 5.1118 0.9998 221125_WJC_METTL3_EV_vs_WT_F08.04909.04909.2 2.13E-05 22-Nov R.STDSEVSQSPAK.N "sp|O75175|CNOT3_HUMAN,tr|B7Z6J7|B7Z6J7_HUMAN,tr|A0A2H2FJL5|A0A2H2FJL5_HUMAN,tr|H7C3F5|H7C3F5_HUMAN,tr|A0A0G2JNJ7|A0A0G2JNJ7_HUMAN,tr|H7C148|H7C148_HUMAN" 6 1234.5677 2.95 111019 4909 2 1234.566009 618.2911 CCR4-NOT transcription complex subunit 3 OS=Homo sapiens OX=9606 GN=CNOT3 PE=1 SV=1 4.37 1458.4 - 273758 - - - -1.39 - 2.144 0.475 - 459.5 1 2 0 -0.0017 12 0 0 0 2.69E+07 9.10E+06 - - - 4.5555 0.9579 221125_WJC_METTL3_EV_vs_WT_F08.04912.04912.3 999 Jan-56 -.MGC[160.03]C[160.03]GC[160.03]GSC[160.03]GGC[160.03]GGR[166.11].C sp|A0A286YEV6|SCGR4_HUMAN 1 1601.4959 0.001 111021 4912 3 1601.491858 534.8393 Small cysteine and glycine repeat-containing protein 4 OS=Homo sapiens OX=9606 GN=SCYGR4 PE=1 SV=1 7.61 1458.8 - 526824 - - - -2.5539 - 0.362 0.518 - 1 2 2 0 -0.0041 15 0 0 0 0.00E+00 1.17E+07 - - - 1.5233 0.9997 221125_WJC_METTL3_EV_vs_WT_F08.04914.04914.3 2.41 Dec-44 R.K[136.11]TVGVEPAADGK[136.11].G "sp|P46779|RL28_HUMAN,tr|H0YMF4|H0YMF4_HUMAN,tr|H0YLP6|H0YLP6_HUMAN,tr|H0YKD8|H0YKD8_HUMAN" 4 1186.6529 1.05 111023 4914 3 1186.653408 396.5582 60S ribosomal protein L28 OS=Homo sapiens OX=9606 GN=RPL28 PE=1 SV=3 6.07 1458.9 - 1.23E+06 - - - 0.4685 - 2.515 0.271 - 243.4 1 2 0 0.0006 12 0 0 0 2.61E+07 2.49E+07 - - - 4.1176 0.9997 221125_WJC_METTL3_EV_vs_WT_F08.04918.04918.2 1.56E-06 13/22 R.KTVGVEPAADGK.G "sp|P46779|RL28_HUMAN,tr|H0YMF4|H0YMF4_HUMAN,tr|H0YLP6|H0YLP6_HUMAN,tr|H0YKD8|H0YKD8_HUMAN" 4 1170.6245 1.02 111027 4918 2 1170.625861 586.3195 60S ribosomal protein L28 OS=Homo sapiens OX=9606 GN=RPL28 PE=1 SV=3 6.07 1459.4 - 143326 - - - 1.2036 - 2.748 0.349 - 452.7 1 2 0 0.0014 12 0 0 0 7.71E+06 7.55E+06 - - - 4.2781 0.9999 221125_WJC_METTL3_EV_vs_WT_F08.04921.04921.2 1.06E-06 22-Dec K.NEPQNATGAPGR[166.11].N sp|P51148|RAB5C_HUMAN 1 1220.5773 1.34 111029 4921 2 1220.577495 611.2959 Ras-related protein Rab-5C OS=Homo sapiens OX=9606 GN=RAB5C PE=1 SV=2 6 1459.8 - 846364 - - - 0.1327 - 2.052 0.555 - 426.7 1 2 0 0.0002 12 0 0 0 5.47E+07 4.08E+07 - - - 5.0315 1 221125_WJC_METTL3_EV_vs_WT_F08.04923.04923.3 0.00775 Dec-44 R.KTVGVEPAADGK.G "sp|P46779|RL28_HUMAN,tr|H0YMF4|H0YMF4_HUMAN,tr|H0YLP6|H0YLP6_HUMAN,tr|H0YKD8|H0YKD8_HUMAN" 4 1170.6245 1.04 111030 4923 3 1170.624644 391.2154 60S ribosomal protein L28 OS=Homo sapiens OX=9606 GN=RPL28 PE=1 SV=3 6.07 1460 - 2.51E+06 - - - 0.164 - 2.485 0.478 - 260 1 2 0 0.0002 12 0 0 0 2.58E+07 2.49E+07 - - - 6.3923 0.9998 221125_WJC_METTL3_EV_vs_WT_F08.04925.04925.2 1.91E-05 20-Oct K.ANSSATETINK.L sp|P15924|DESP_HUMAN 1 1134.5517 16.08 111032 4925 2 1134.551533 568.2831 Desmoplakin OS=Homo sapiens OX=9606 GN=DSP PE=1 SV=3 6.05 1460.1 - 3.17E+06 - - - -0.1304 - 2.275 0.371 - 467.6 1 2 0 -0.0001 11 0 0 0 9.30E+07 5.78E+06 - - - 4.0048 1 221125_WJC_METTL3_EV_vs_WT_F08.04930.04930.2 1.41E-05 17/22 R.K[136.11]TVGVEPAADGK[136.11].G "sp|P46779|RL28_HUMAN,tr|H0YMF4|H0YMF4_HUMAN,tr|H0YLP6|H0YLP6_HUMAN,tr|H0YKD8|H0YKD8_HUMAN" 4 1186.6529 1.02 111037 4930 2 1186.652489 594.3337 60S ribosomal protein L28 OS=Homo sapiens OX=9606 GN=RPL28 PE=1 SV=3 6.07 1460.6 - 718520 - - - -0.3059 - 2.966 0.519 - 838.2 1 2 0 -0.0004 12 0 0 0 7.71E+06 7.55E+06 - - - 5.7349 1 221125_WJC_METTL3_EV_vs_WT_F08.04939.04939.3 0.000619 Dec-48 R.RPAPSGGASGDLR.A sp|P47974|TISD_HUMAN 1 1239.632 2.02 111044 4939 3 1239.632545 414.2179 mRNA decay activator protein ZFP36L2 OS=Homo sapiens OX=9606 GN=ZFP36L2 PE=1 SV=3 9.6 1461.6 - 999525 - - - 0.4421 - 2.371 0.458 - 251.6 1 2 0 0.0005 13 0 0 0 3.44E+07 1.70E+07 - - - 5.9868 1 221125_WJC_METTL3_EV_vs_WT_F08.04941.04941.3 0.00384 18/48 K.NGGGVGGGELDK[136.11]K[136.11].D sp|Q9H7S9|ZN703_HUMAN 1 1202.6226 1.62 111045 4941 3 1202.622221 401.8815 Zinc finger protein 703 OS=Homo sapiens OX=9606 GN=ZNF703 PE=1 SV=1 6.07 1461.8 - 5.61E+06 - - - -0.3276 - 2.834 0.501 - 697.4 1 2 0 -0.0004 13 0 0 0 4.92E+08 3.04E+08 - - - 6.9499 1 221125_WJC_METTL3_EV_vs_WT_F08.04943.04943.3 0.000505 19/48 K.NGGGVGGGELDKK.D sp|Q9H7S9|ZN703_HUMAN 1 1186.5942 1.51 111047 4943 3 1186.595871 396.5387 Zinc finger protein 703 OS=Homo sapiens OX=9606 GN=ZNF703 PE=1 SV=1 6.07 1461.9 - 6.56E+06 - - - 1.3956 - 2.841 0.463 - 546.2 1 2 0 0.0017 13 0 0 0 4.95E+08 3.28E+08 - - - 6.5325 0.9994 221125_WJC_METTL3_EV_vs_WT_F08.04945.04945.2 1.36E-05 24-Dec K.DADSQNPDAPEGK[136.11].R "sp|P53621|COPA_HUMAN,tr|A0A3B3ISC6|A0A3B3ISC6_HUMAN,tr|A0A3B3ITV3|A0A3B3ITV3_HUMAN,tr|A0A3B3IS84|A0A3B3IS84_HUMAN,tr|A0A3B3IU89|A0A3B3IU89_HUMAN,tr|A0A3B3ISK1|A0A3B3ISK1_HUMAN,tr|A0A3B3IT15|A0A3B3IT15_HUMAN" 7 1350.5779 0.32 111049 4945 2 1350.576352 676.2962 Coatomer subunit alpha OS=Homo sapiens OX=9606 GN=COPA PE=1 SV=2 3.84 1462.1 - 1.40E+06 - - - -1.1484 - 2.223 0.273 - 471.3 1 2 0 -0.0015 13 0 0 0 5.11E+06 1.61E+07 - - - 3.1072 0.9999 221125_WJC_METTL3_EV_vs_WT_F08.04946.04946.2 2.45E-05 20-Oct K.VSSFSNSSSNK.E sp|Q5VUA4|ZN318_HUMAN 1 1142.5204 1.36 111050 4946 2 1142.520773 572.2675 Zinc finger protein 318 OS=Homo sapiens OX=9606 GN=ZNF318 PE=1 SV=2 8.72 1462.2 - 989916 - - - 0.3431 - 2.193 0.5 - 475.9 1 2 0 0.0004 11 0 0 0 8.48E+06 6.24E+06 - - - 4.8582 0.9865 221125_WJC_METTL3_EV_vs_WT_F08.04949.04949.2 0.00361 16-Sep K.EQIKTLNNK.F "sp|Q9NSB2|KRT84_HUMAN,sp|P48668|K2C6C_HUMAN,sp|P05787|K2C8_HUMAN,sp|Q01546|K22O_HUMAN,sp|P12035|K2C3_HUMAN,sp|P04259|K2C6B_HUMAN,sp|P13647|K2C5_HUMAN,sp|P35908|K22E_HUMAN,sp|P08729|K2C7_HUMAN,sp|O95678|K2C75_HUMAN,sp|Q5XKE5|K2C79_HUMAN,sp|P02538|K2C6A_HUMAN,tr|F8VUG2|F8VUG2_HUMAN,tr|F8W0C6|F8W0C6_HUMAN,tr|F8W1U3|F8W1U3_HUMAN,tr|F8VQY3|F8VQY3_HUMAN,tr|F8VU69|F8VU69_HUMAN" 17 1086.6033 0.84 111053 4949 2 1086.603583 544.3089 "Keratin, type II cuticular Hb4 OS=Homo sapiens OX=9606 GN=KRT84 PE=2 SV=2" 8.69 1462.5 - 614941 - - - 0.2393 - 1.698 0.223 - 266.5 1 2 1 0.0003 9 0 0 0 3.31E+06 3.95E+06 - - - 2.2197 0.9804 221125_WJC_METTL3_EV_vs_WT_F08.04950.04950.3 6.74E-06 Oct-40 F.SLEDPQTHSNR[166.11].L sp|P08238|HS90B_HUMAN 1 1292.5985 0.73 111054 4950 3 1292.597881 431.8734 Heat shock protein HSP 90-beta OS=Homo sapiens OX=9606 GN=HSP90AB1 PE=1 SV=4 5.3 1462.6 - 429528 - - - -0.4495 - 2.134 0.351 - 110.4 1 1 0 -0.0006 11 0 0 0 5.81E+06 7.99E+06 - - - 4.6065 0.9706 221125_WJC_METTL3_EV_vs_WT_F08.04952.04952.2 0.106 16-Aug R.TK[136.11]VEIANSR[166.11].T sp|Q9HDC5|JPH1_HUMAN 1 1034.5839 2.63 111056 4952 2 1034.586855 518.2992 Junctophilin-1 OS=Homo sapiens OX=9606 GN=JPH1 PE=1 SV=2 8.41 1462.8 - 313992 - - - 2.8292 - 1.635 0.309 - 206.1 1 2 1 0.0029 9 0 0 0 5.83E+06 2.22E+06 - - - 2.7447 1 221125_WJC_METTL3_EV_vs_WT_F08.04953.04953.2 1.48E-06 13/24 K.DADSQNPDAPEGK.R "sp|P53621|COPA_HUMAN,tr|A0A3B3ISC6|A0A3B3ISC6_HUMAN,tr|A0A3B3ITV3|A0A3B3ITV3_HUMAN,tr|A0A3B3IS84|A0A3B3IS84_HUMAN,tr|A0A3B3IU89|A0A3B3IU89_HUMAN,tr|A0A3B3ISK1|A0A3B3ISK1_HUMAN,tr|A0A3B3IT15|A0A3B3IT15_HUMAN" 7 1342.5637 0.34 111057 4953 2 1342.562176 672.2891 Coatomer subunit alpha OS=Homo sapiens OX=9606 GN=COPA PE=1 SV=2 3.84 1463 - 292373 - - - -1.1374 - 2.701 0.614 - 613.3 1 2 0 -0.0015 13 0 0 0 5.48E+06 1.61E+07 - - - 6.1257 0.9997 221125_WJC_METTL3_EV_vs_WT_F08.04965.04965.3 0.000249 Oct-32 R.YEREQYADR.A sp|Q9BWF3|RBM4_HUMAN 1 1228.5473 1.44 111066 4965 3 1228.545405 410.523 RNA-binding protein 4 OS=Homo sapiens OX=9606 GN=RBM4 PE=1 SV=1 4.68 1464.4 - 2.43E+06 - - - -1.514 - 1.987 0.47 - 128.8 1 2 1 -0.0019 9 0 0 0 1.93E+07 1.34E+07 - - - 5.8489 0.9989 221125_WJC_METTL3_EV_vs_WT_F08.04966.04966.3 0.00635 Nov-32 R.YER[166.11]EQYADR[166.11].A sp|Q9BWF3|RBM4_HUMAN 1 1248.5638 1.33 111067 4966 3 1248.563503 417.1952 RNA-binding protein 4 OS=Homo sapiens OX=9606 GN=RBM4 PE=1 SV=1 4.68 1464.4 - 2.10E+06 - - - -0.2419 - 1.878 0.358 - 143.7 1 2 1 -0.0003 9 0 0 0 1.92E+07 1.45E+07 - - - 4.4306 0.9812 221125_WJC_METTL3_EV_vs_WT_F08.04968.04968.2 0.00069 22-Oct N.GGGVGGGELDKK.D sp|Q9H7S9|ZN703_HUMAN 1 1072.5513 0.36 111069 4968 2 1072.552344 537.2829 Zinc finger protein 703 OS=Homo sapiens OX=9606 GN=ZNF703 PE=1 SV=1 6.07 1464.6 - 1.01E+06 - - - 0.9855 - 1.8 0.439 - 269.7 1 1 0 0.0011 12 0 0 0 1.06E+07 2.96E+07 - - - 3.8297 0.9964 221125_WJC_METTL3_EV_vs_WT_F08.04970.04970.2 0.00577 18-Sep R.RLSYNTASNK.T sp|P49207|RL34_HUMAN 1 1152.5887 1.18 111071 4970 2 1152.584847 577.3016 60S ribosomal protein L34 OS=Homo sapiens OX=9606 GN=RPL34 PE=1 SV=3 9.99 1464.8 - 889816 - - - -3.3741 - 1.743 0.303 - 234 1 2 0 -0.0039 10 0 0 0 1.21E+07 1.02E+07 - - - 2.8286 0.9999 221125_WJC_METTL3_EV_vs_WT_F08.04974.04974.2 4.29E-06 22-Dec R.FSSSTEQSSASR.L "sp|Q92997|DVL3_HUMAN,sp|O14641|DVL2_HUMAN,tr|I3L0M7|I3L0M7_HUMAN,tr|A0A3B3ITC6|A0A3B3ITC6_HUMAN,tr|I3L2W9|I3L2W9_HUMAN,tr|I3L2N2|I3L2N2_HUMAN" 6 1272.5582 0.63 111075 4974 2 1272.557716 637.2864 Segment polarity protein dishevelled homolog DVL-3 OS=Homo sapiens OX=9606 GN=DVL3 PE=1 SV=2 6 1465.2 - 464722 - - - -0.3984 - 2.455 0.551 - 510.6 1 2 0 -0.0005 12 0 0 0 5.91E+06 9.43E+06 - - - 5.4737 0.9642 221125_WJC_METTL3_EV_vs_WT_F08.04975.04975.2 0.123 14-Nov K.LRDDFEKK.M "sp|Q9Y2W1|TR150_HUMAN,tr|A0A3B3ITZ9|A0A3B3ITZ9_HUMAN" 2 1049.5506 2.75 111076 4975 2 1049.553069 525.7826 Thyroid hormone receptor-associated protein 3 OS=Homo sapiens OX=9606 GN=THRAP3 PE=1 SV=2 6.12 1465.4 - 403897 - - - 2.3915 - 1.883 0.181 - 445.9 1 2 1 0.0025 8 0 0 0 1.85E+09 6.75E+08 - - - 2.2858 0.9593 221125_WJC_METTL3_EV_vs_WT_F08.04977.04977.2 0.03 20-Sep G.GGVGGGELDK[136.11]K[136.11].D sp|Q9H7S9|ZN703_HUMAN 1 1031.5582 1.56 111078 4977 2 1031.558575 516.7864 Zinc finger protein 703 OS=Homo sapiens OX=9606 GN=ZNF703 PE=1 SV=1 6.07 1465.6 - 298419 - - - 0.3403 - 1.664 0.313 - 181 1 1 0 0.0004 11 0 0 0 4.61E+06 2.96E+06 - - - 2.7303 0.9999 221125_WJC_METTL3_EV_vs_WT_F08.04983.04983.3 6.02E-05 14/36 R.LHEADATLK[136.11]R[166.11].E sp|Q8TBA6|GOGA5_HUMAN 1 1170.6476 5.72 111082 4983 3 1170.649727 391.2231 Golgin subfamily A member 5 OS=Homo sapiens OX=9606 GN=GOLGA5 PE=1 SV=3 6.75 1466.3 - 2.45E+06 - - - 1.8246 - 2.624 0.363 - 413.3 1 2 0 0.0021 10 0 0 0 8.70E+07 1.52E+07 - - - 5.4038 0.9999 221125_WJC_METTL3_EV_vs_WT_F08.04985.04985.2 0.000661 22-Nov R.FSSSTEQSSASR[166.11].L "sp|Q92997|DVL3_HUMAN,sp|O14641|DVL2_HUMAN,tr|I3L0M7|I3L0M7_HUMAN,tr|A0A3B3ITC6|A0A3B3ITC6_HUMAN,tr|I3L2W9|I3L2W9_HUMAN,tr|I3L2N2|I3L2N2_HUMAN" 6 1282.5665 0.63 111084 4985 2 1282.566119 642.2905 Segment polarity protein dishevelled homolog DVL-3 OS=Homo sapiens OX=9606 GN=DVL3 PE=1 SV=2 6 1466.4 - 1.46E+06 - - - -0.2916 - 2.371 0.573 - 356.2 1 2 0 -0.0004 12 0 0 0 5.91E+06 9.43E+06 - - - 5.5446 0.999 221125_WJC_METTL3_EV_vs_WT_F08.04990.04990.2 0.00419 16-Aug K.C[160.03]THWAEGGK.G "sp|P11586|C1TC_HUMAN,tr|F5H2F4|F5H2F4_HUMAN,tr|V9GZ78|V9GZ78_HUMAN,tr|V9GYY3|V9GYY3_HUMAN,tr|A0A494C1T2|A0A494C1T2_HUMAN" 5 1044.4447 0.55 111089 4990 2 1044.442339 523.2296 "C-1-tetrahydrofolate synthase, cytoplasmic OS=Homo sapiens OX=9606 GN=MTHFD1 PE=1 SV=4" 6.74 1467 - 300585 - - - -2.2739 - 1.267 0.484 - 52.1 1 2 0 -0.0024 9 0 0 0 1.51E+06 2.73E+06 - - - 3.2997 0.9999 221125_WJC_METTL3_EV_vs_WT_F08.04992.04992.2 1.28E-06 13/26 K.LEGNSPQGSNQGVK.L sp|P61006|RAB8A_HUMAN 1 1413.6848 1.13 111091 4992 2 1413.685505 707.8497 Ras-related protein Rab-8A OS=Homo sapiens OX=9606 GN=RAB8A PE=1 SV=1 6 1467.2 - 151080 - - - 0.4838 - 2.218 0.516 - 384.5 1 2 0 0.0007 14 0 0 0 1.07E+08 9.52E+07 - - - 4.851 1 221125_WJC_METTL3_EV_vs_WT_F08.04994.04994.2 1.50E-07 16/24 K.NGGGVGGGELDKK.D sp|Q9H7S9|ZN703_HUMAN 1 1186.5942 1.49 111092 4994 2 1186.593888 594.3044 Zinc finger protein 703 OS=Homo sapiens OX=9606 GN=ZNF703 PE=1 SV=1 6.07 1467.5 - 1.08E+07 - - - -0.2756 - 3.008 0.641 - 803.4 1 2 0 -0.0003 13 0 0 0 9.57E+07 6.44E+07 - - - 6.6018 1 221125_WJC_METTL3_EV_vs_WT_F08.04998.04998.2 3.60E-07 15/26 K.LEGNSPQGSNQGVK[136.11].L sp|P61006|RAB8A_HUMAN 1 1421.699 1.13 111095 4998 2 1421.699225 711.8568 Ras-related protein Rab-8A OS=Homo sapiens OX=9606 GN=RAB8A PE=1 SV=1 6 1467.9 - 1.28E+06 - - - 0.1435 - 2.738 0.566 - 640.5 1 2 0 0.0002 14 0 0 0 1.07E+08 9.52E+07 - - - 5.749 0.9997 221125_WJC_METTL3_EV_vs_WT_F08.05002.05002.2 7.89E-07 20-Nov K.QQTNNQTEVVK[136.11].L "sp|Q5BKZ1|ZN326_HUMAN,tr|A0A0A0MRN4|A0A0A0MRN4_HUMAN" 2 1295.6561 1.51 111099 5002 2 1295.653588 648.8353 DBIRD complex subunit ZNF326 OS=Homo sapiens OX=9606 GN=ZNF326 PE=1 SV=2 6 1468.4 - 503957 - - - -1.9334 - 2.078 0.516 - 232.5 1 2 0 -0.0025 11 0 0 0 1.73E+08 1.15E+08 - - - 4.83 0.9998 221125_WJC_METTL3_EV_vs_WT_F08.05007.05007.2 1.05E-05 20-Sep K.QQTNNQTEVVK.L "sp|Q5BKZ1|ZN326_HUMAN,tr|A0A0A0MRN4|A0A0A0MRN4_HUMAN" 2 1287.6419 1.51 111102 5007 2 1287.640327 644.8282 DBIRD complex subunit ZNF326 OS=Homo sapiens OX=9606 GN=ZNF326 PE=1 SV=2 6 1469 - 2.39E+06 - - - -1.2162 - 2.136 0.505 - 334.7 1 2 0 -0.0016 11 0 0 0 1.73E+08 1.15E+08 - - - 4.8235 0.9977 221125_WJC_METTL3_EV_vs_WT_F08.05008.05008.2 0.0456 22-Aug R.ARPQPSGPAPSS.- sp|Q96MG7|NSE3_HUMAN 1 1150.5731 0.37 111103 5008 2 1150.572599 576.2938 Non-structural maintenance of chromosomes element 3 homolog OS=Homo sapiens OX=9606 GN=NSMCE3 PE=1 SV=1 9.79 1469.1 - 1.57E+06 - - - -0.4224 - 1.461 0.244 - 160.5 2 2 0 -0.0005 12 0 0 0 3.56E+07 9.57E+07 - - - 1.7061 0.9998 221125_WJC_METTL3_EV_vs_WT_F08.05010.05010.2 3.59E-06 16-Dec K.R[166.11]QEEEEVVR[166.11].K sp|Q9BYJ9|YTHD1_HUMAN 1 1192.5951 1.52 111105 5010 2 1192.593927 597.3048 YTH domain-containing family protein 1 OS=Homo sapiens OX=9606 GN=YTHDF1 PE=1 SV=1 4.49 1469.3 - 950898 - - - -0.9878 - 2.581 0.346 - 258.2 1 2 0 -0.0012 9 0 0 0 6.39E+07 4.22E+07 - - - 4.3393 0.9986 221125_WJC_METTL3_EV_vs_WT_F08.05011.05011.2 0.00086 16-Sep R.QSNVIADHR.D "sp|P49750|YLPM1_HUMAN,tr|H0YIQ2|H0YIQ2_HUMAN,tr|F8VU51|F8VU51_HUMAN,tr|H0YI23|H0YI23_HUMAN" 4 1038.5207 0.81 111106 5011 2 1038.517357 520.2676 YLP motif-containing protein 1 OS=Homo sapiens OX=9606 GN=YLPM1 PE=1 SV=4 6.74 1469.5 - 649806 - - - -3.1766 - 1.863 0.384 - 262.2 1 2 0 -0.0033 9 0 0 0 9.31E+06 1.15E+07 - - - 3.6762 0.9997 221125_WJC_METTL3_EV_vs_WT_F08.05014.05014.2 0.000319 22-Sep R.AR[166.11]PQPSGPAPSS.- sp|Q96MG7|NSE3_HUMAN 1 1160.5814 1.74 111108 5014 2 1160.580889 581.298 Non-structural maintenance of chromosomes element 3 homolog OS=Homo sapiens OX=9606 GN=NSMCE3 PE=1 SV=1 9.79 1469.8 - 547930 - - - -0.4015 - 1.7 0.439 - 159.5 1 2 0 -0.0005 12 0 0 0 3.01E+07 1.73E+07 - - - 3.6795 1 221125_WJC_METTL3_EV_vs_WT_F08.05017.05017.3 2.05E-05 Oct-32 K.EYVTC[160.03]HTC[160.03]R[166.11].S sp|P20042|IF2B_HUMAN 1 1234.5098 1.42 111110 5017 3 1234.507712 412.5106 Eukaryotic translation initiation factor 2 subunit 2 OS=Homo sapiens OX=9606 GN=EIF2S2 PE=1 SV=2 6.82 1470.1 - 2.43E+06 - - - -1.7294 - 2.193 0.545 - 306.2 1 2 0 -0.0021 9 0 0 0 8.83E+07 6.22E+07 - - - 6.9823 0.9991 221125_WJC_METTL3_EV_vs_WT_F08.05018.05018.2 0.00258 14/16 K.RQEEEEVVR.K sp|Q9BYJ9|YTHD1_HUMAN 1 1172.5786 1.52 111111 5018 2 1172.573744 587.2966 YTH domain-containing family protein 1 OS=Homo sapiens OX=9606 GN=YTHDF1 PE=1 SV=1 4.49 1470.2 - 2.65E+06 - - - -4.1115 - 2.639 0.485 - 402.1 1 2 0 -0.0048 9 0 0 0 6.39E+07 4.22E+07 - - - 5.4291 0.9619 221125_WJC_METTL3_EV_vs_WT_F08.05026.05026.2 3.78 16-Oct R.LRSEIDHVK.K "sp|P48668|K2C6C_HUMAN,sp|P04259|K2C6B_HUMAN,sp|P02538|K2C6A_HUMAN" 3 1095.6037 999 111117 5026 2 1095.601212 548.8091 "Keratin, type II cytoskeletal 6C OS=Homo sapiens OX=9606 GN=KRT6C PE=1 SV=3" 6.75 1471.1 - 2.49E+06 - - - -2.2316 - 1.873 0.167 - 355.8 1 2 1 -0.0024 9 0 0 0 5.24E+08 0.00E+00 - - - 2.0892 0.9583 221125_WJC_METTL3_EV_vs_WT_F08.05028.05028.2 0.00264 12-Aug L.R[166.11]DDFEK[136.11]K[136.11].M "sp|Q9Y2W1|TR150_HUMAN,tr|A0A3B3ITZ9|A0A3B3ITZ9_HUMAN" 2 962.5032 3.59 111119 5028 2 962.501291 482.2589 Thyroid hormone receptor-associated protein 3 OS=Homo sapiens OX=9606 GN=THRAP3 PE=1 SV=2 6.12 1471.3 - 2.31E+06 - - - -1.947 - 1.652 0.376 - 246 1 1 0 -0.0019 7 0 0 0 1.29E+08 3.58E+07 - - - 3.4081 0.9998 221125_WJC_METTL3_EV_vs_WT_F08.05031.05031.2 3.72E-05 16-Aug K.EYVTC[160.03]HTC[160.03]R[166.11].S sp|P20042|IF2B_HUMAN 1 1234.5098 1.24 111122 5031 2 1234.5079 618.2622 Eukaryotic translation initiation factor 2 subunit 2 OS=Homo sapiens OX=9606 GN=EIF2S2 PE=1 SV=2 6.82 1471.6 - 546510 - - - -1.5771 - 1.67 0.597 - 199.5 1 2 0 -0.0019 9 0 0 0 6.69E+06 5.41E+06 - - - 4.9335 0.9997 221125_WJC_METTL3_EV_vs_WT_F08.05037.05037.2 0.00655 13/16 R.HLTGEFEKK.Y "sp|P62826|RAN_HUMAN,tr|H0YFC6|H0YFC6_HUMAN,tr|B5MDF5|B5MDF5_HUMAN,tr|J3KQE5|J3KQE5_HUMAN,tr|F5H018|F5H018_HUMAN" 5 1087.5662 0.85 111126 5037 2 1087.566074 544.7904 GTP-binding nuclear protein Ran OS=Homo sapiens OX=9606 GN=RAN PE=1 SV=3 6.76 1472.3 - 989898 - - - -0.1241 - 1.988 0.347 - 341.5 1 2 0 -0.0001 9 0 0 0 1.29E+07 1.52E+07 - - - 3.5918 0.9997 221125_WJC_METTL3_EV_vs_WT_F08.05042.05042.2 9.97E-05 20-Oct K.SVESTSPEPSK.L sp|P18583|SON_HUMAN 1 1146.5404 2.41 111129 5042 2 1146.538381 574.2775 Protein SON OS=Homo sapiens OX=9606 GN=SON PE=1 SV=4 4.53 1473 - 1.27E+06 - - - -1.8028 - 1.913 0.479 - 265.2 1 2 0 -0.0021 11 0 0 0 2.67E+07 1.11E+07 - - - 4.3331 0.9986 221125_WJC_METTL3_EV_vs_WT_F08.05047.05047.3 0.257 Nov-40 K.QVHPDTGISSK.A "sp|Q8N257|H2B3B_HUMAN,sp|P33778|H2B1B_HUMAN,sp|Q96A08|H2B1A_HUMAN,sp|Q5QNW6|H2B2F_HUMAN,sp|P58876|H2B1D_HUMAN,sp|Q99880|H2B1L_HUMAN,sp|P62807|H2B1C_HUMAN,sp|Q99877|H2B1N_HUMAN,sp|P57053|H2BFS_HUMAN,sp|P23527|H2B1O_HUMAN,sp|O60814|H2B1K_HUMAN,sp|Q93079|H2B1H_HUMAN,sp|Q99879|H2B1M_HUMAN,sp|Q16778|H2B2E_HUMAN,sp|P06899|H2B1J_HUMAN,tr|U3KQK0|U3KQK0_HUMAN" 16 1167.5884 1.08 111132 5047 3 1167.584561 390.2034 Histone H2B type 3-B OS=Homo sapiens OX=9606 GN=H2BU1 PE=1 SV=3 6.74 1473.6 - 2.38E+07 - - - -3.2888 - 1.836 0.354 - 181.8 1 2 0 -0.0038 11 0 0 0 5.40E+09 5.02E+09 - - - 4.2117 0.9999 221125_WJC_METTL3_EV_vs_WT_F08.05048.05048.2 0.00157 16-Nov K.HIGYDDSSK.G sp|P31153|METK2_HUMAN 1 1020.4512 1.19 111133 5048 2 1020.449859 511.2329 S-adenosylmethionine synthase isoform type-2 OS=Homo sapiens OX=9606 GN=MAT2A PE=1 SV=1 5.21 1473.6 - 7.54E+06 - - - -1.3523 - 2.044 0.623 - 399.9 1 2 0 -0.0014 9 0 0 0 1.41E+08 1.18E+08 - - - 5.7103 0.9999 221125_WJC_METTL3_EV_vs_WT_F08.05050.05050.2 5.39E-05 14/20 K.QVHPDTGISSK[136.11].A "sp|Q8N257|H2B3B_HUMAN,sp|P33778|H2B1B_HUMAN,sp|Q96A08|H2B1A_HUMAN,sp|Q5QNW6|H2B2F_HUMAN,sp|P58876|H2B1D_HUMAN,sp|Q99880|H2B1L_HUMAN,sp|P62807|H2B1C_HUMAN,sp|Q99877|H2B1N_HUMAN,sp|P57053|H2BFS_HUMAN,sp|P23527|H2B1O_HUMAN,sp|O60814|H2B1K_HUMAN,sp|Q93079|H2B1H_HUMAN,sp|Q99879|H2B1M_HUMAN,sp|Q16778|H2B2E_HUMAN,sp|P06899|H2B1J_HUMAN,tr|U3KQK0|U3KQK0_HUMAN" 16 1175.6026 1.09 111135 5050 2 1175.602041 588.8086 Histone H2B type 3-B OS=Homo sapiens OX=9606 GN=H2BU1 PE=1 SV=3 6.74 1473.8 - 3.82E+06 - - - -0.4764 - 2.215 0.458 - 610 1 2 0 -0.0006 11 0 0 0 9.66E+08 8.88E+08 - - - 4.575 0.9999 221125_WJC_METTL3_EV_vs_WT_F08.05052.05052.2 1.88E-05 20-Nov K.QVHPDTGISSK.A "sp|Q8N257|H2B3B_HUMAN,sp|P33778|H2B1B_HUMAN,sp|Q96A08|H2B1A_HUMAN,sp|Q5QNW6|H2B2F_HUMAN,sp|P58876|H2B1D_HUMAN,sp|Q99880|H2B1L_HUMAN,sp|P62807|H2B1C_HUMAN,sp|Q99877|H2B1N_HUMAN,sp|P57053|H2BFS_HUMAN,sp|P23527|H2B1O_HUMAN,sp|O60814|H2B1K_HUMAN,sp|Q93079|H2B1H_HUMAN,sp|Q99879|H2B1M_HUMAN,sp|Q16778|H2B2E_HUMAN,sp|P06899|H2B1J_HUMAN,tr|U3KQK0|U3KQK0_HUMAN" 16 1167.5884 1.09 111136 5052 2 1167.587252 584.8015 Histone H2B type 3-B OS=Homo sapiens OX=9606 GN=H2BU1 PE=1 SV=3 6.74 1474 - 5.98E+06 - - - -0.9841 - 2.205 0.51 - 393.9 1 2 0 -0.0011 11 0 0 0 9.66E+08 8.88E+08 - - - 4.9466 1 221125_WJC_METTL3_EV_vs_WT_F08.05058.05058.2 8.76E-10 15/26 K.ATC[160.03]GTVGDDNEEAK.R sp|P38432|COIL_HUMAN 1 1465.5991 1.16 111139 5058 2 1465.595435 733.8068 Coilin OS=Homo sapiens OX=9606 GN=COIL PE=1 SV=1 3.92 1474.6 - 693519 - - - -2.502 - 2.896 0.656 - 698.5 1 2 0 -0.0037 14 0 0 0 2.19E+07 1.88E+07 - - - 6.5534 0.9998 221125_WJC_METTL3_EV_vs_WT_F08.05065.05065.2 0.00591 16-Dec K.HIGYDDSSK[136.11].G sp|P31153|METK2_HUMAN 1 1028.4654 1.19 111143 5065 2 1028.464045 515.24 S-adenosylmethionine synthase isoform type-2 OS=Homo sapiens OX=9606 GN=MAT2A PE=1 SV=1 5.21 1475.5 - 5.15E+06 - - - -1.3554 - 1.908 0.489 - 305.3 1 2 0 -0.0014 9 0 0 0 1.41E+08 1.18E+08 - - - 4.5214 0.9897 221125_WJC_METTL3_EV_vs_WT_F08.05066.05066.3 0.104 Dec-48 R.EAEREGATEEAVR.E sp|Q9BV20|MTNA_HUMAN 1 1445.6746 2.02 111144 5066 3 1445.673079 482.8988 Methylthioribose-1-phosphate isomerase OS=Homo sapiens OX=9606 GN=MRI1 PE=1 SV=1 4.33 1475.6 - 1.63E+06 - - - -1.0867 - 1.859 0.229 - 160.5 1 2 1 -0.0016 13 0 0 0 1.43E+07 7.08E+06 - - - 2.7738 0.9987 221125_WJC_METTL3_EV_vs_WT_F08.05068.05068.2 0.292 18-Aug K.HILQQQETSR.L tr|J3QS41|J3QS41_HUMAN 1 1238.6367 999 111146 5068 2 1238.637341 620.3257 Probable helicase with zinc finger domain OS=Homo sapiens OX=9606 GN=HELZ PE=1 SV=1 6.75 1475.9 - 615080 - - - 0.4788 - 1.751 0.237 - 156.2 2 2 0 0.0006 10 0 0 0 9.84E+06 0.00E+00 - - - 2.2205 0.9995 221125_WJC_METTL3_EV_vs_WT_F08.05069.05069.2 0.0207 16-Nov R.RDNQFDSPK.R "sp|O14654|IRS4_HUMAN,tr|A0A804CF45|A0A804CF45_HUMAN" 2 1105.5152 1.42 111147 5069 2 1105.513689 553.7649 Insulin receptor substrate 4 OS=Homo sapiens OX=9606 GN=IRS4 PE=1 SV=1 5.96 1476 - 495789 - - - -1.3993 - 2.048 0.323 - 328.9 1 2 0 -0.0015 9 0 0 0 8.90E+07 6.27E+07 - - - 3.5001 0.9971 221125_WJC_METTL3_EV_vs_WT_F08.05079.05079.2 0.00101 20-Oct K.STSTPTSPGPR.T "sp|Q8WWM7|ATX2L_HUMAN,tr|A0A0C4DGL7|A0A0C4DGL7_HUMAN,tr|H3BUF6|H3BUF6_HUMAN,tr|H3BRB0|H3BRB0_HUMAN" 4 1086.5306 1.42 111155 5079 2 1086.525701 544.2726 Ataxin-2-like protein OS=Homo sapiens OX=9606 GN=ATXN2L PE=1 SV=2 9.47 1476.9 - 952466 - - - -4.4647 - 1.805 0.446 - 323.1 1 2 0 -0.0049 11 0 0 0 6.12E+07 4.30E+07 - - - 3.9312 0.9951 221125_WJC_METTL3_EV_vs_WT_F08.05083.05083.3 0.000604 13/36 R.LRSEIDNVKK.Q sp|P04264|K2C1_HUMAN 1 1200.6826 2606.11 111157 5083 3 1200.679807 401.2348 "Keratin, type II cytoskeletal 1 OS=Homo sapiens OX=9606 GN=KRT1 PE=1 SV=6" 8.59 1477.4 - 4.98E+06 - - - -2.3562 - 2.424 0.248 - 220.3 1 2 1 -0.0028 10 0 0 0 3.97E+08 1.52E+05 - - - 3.89 0.9996 221125_WJC_METTL3_EV_vs_WT_F08.05084.05084.2 0.109 16-Dec R.R[166.11]TDEATFSK[136.11].L "sp|Q53H12|AGK_HUMAN,tr|E9PC15|E9PC15_HUMAN,tr|A0A3B3ITV0|A0A3B3ITV0_HUMAN,tr|A0A3B3ITX7|A0A3B3ITX7_HUMAN,tr|E9PG39|E9PG39_HUMAN,tr|A0A3B3ITD0|A0A3B3ITD0_HUMAN,tr|A0A3B3IUC9|A0A3B3IUC9_HUMAN,tr|A0A3B3ISY9|A0A3B3ISY9_HUMAN,tr|A0A3B3ISZ0|A0A3B3ISZ0_HUMAN" 9 1071.5316 1.38 111158 5084 2 1071.530925 536.7731 "Acylglycerol kinase, mitochondrial OS=Homo sapiens OX=9606 GN=AGK PE=1 SV=2" 6.07 1477.5 - 3.00E+06 - - - -0.5907 - 2.041 0.301 - 628.3 1 2 0 -0.0006 9 0 0 0 8.54E+07 6.19E+07 - - - 3.328 0.9995 221125_WJC_METTL3_EV_vs_WT_F08.05086.05086.2 0.096 16-Dec R.RTDEATFSK.L "sp|Q53H12|AGK_HUMAN,tr|E9PC15|E9PC15_HUMAN,tr|A0A3B3ITV0|A0A3B3ITV0_HUMAN,tr|A0A3B3ITX7|A0A3B3ITX7_HUMAN,tr|E9PG39|E9PG39_HUMAN,tr|A0A3B3ITD0|A0A3B3ITD0_HUMAN,tr|A0A3B3IUC9|A0A3B3IUC9_HUMAN,tr|A0A3B3ISY9|A0A3B3ISY9_HUMAN,tr|A0A3B3ISZ0|A0A3B3ISZ0_HUMAN" 9 1053.5091 1.38 111160 5086 2 1053.510029 527.7618 "Acylglycerol kinase, mitochondrial OS=Homo sapiens OX=9606 GN=AGK PE=1 SV=2" 6.07 1477.6 - 3.01E+06 - - - 0.8932 - 2.116 0.285 - 688 1 2 0 0.0009 9 0 0 0 8.54E+07 6.19E+07 - - - 3.3141 0.9982 221125_WJC_METTL3_EV_vs_WT_F08.05087.05087.3 0.0509 13/44 K.MIASDSHRPEVK.L "sp|Q9NYF8|BCLF1_HUMAN,tr|E9PKI6|E9PKI6_HUMAN,tr|A0A1W2PQ43|A0A1W2PQ43_HUMAN,tr|E9PK91|E9PK91_HUMAN,tr|E9PJA7|E9PJA7_HUMAN,tr|E9PK09|E9PK09_HUMAN,tr|E9PQN2|E9PQN2_HUMAN" 7 1368.682 9.98 111161 5087 3 1368.680702 457.2346 Bcl-2-associated transcription factor 1 OS=Homo sapiens OX=9606 GN=BCLAF1 PE=1 SV=2 6.51 1477.6 - 2.47E+06 - - - -0.9367 - 1.822 0.242 - 218.2 1 2 0 -0.0013 12 0 0 0 1.56E+08 1.56E+07 - - - 2.9006 0.9999 221125_WJC_METTL3_EV_vs_WT_F08.05091.05091.2 4.93E-08 13/26 K.ATC[160.03]GTVGDDNEEAK[136.11].R sp|P38432|COIL_HUMAN 1 1473.6133 1.16 111165 5091 2 1473.612742 737.8139 Coilin OS=Homo sapiens OX=9606 GN=COIL PE=1 SV=1 3.92 1478.1 - 1.22E+06 - - - -0.38 - 2.396 0.585 - 508.4 1 2 0 -0.0006 14 0 0 0 2.19E+07 1.88E+07 - - - 5.5544 1 221125_WJC_METTL3_EV_vs_WT_F08.05093.05093.2 0.000193 15/20 R.K[136.11]AEEDAALQAK[136.11].K "sp|Q13428|TCOF_HUMAN,tr|E7ETY2|E7ETY2_HUMAN,tr|H0YA99|H0YA99_HUMAN,tr|H0Y8Y7|H0Y8Y7_HUMAN,tr|A0A3B3IS06|A0A3B3IS06_HUMAN,tr|A0A2R8Y857|A0A2R8Y857_HUMAN,tr|A0A2R8Y4M7|A0A2R8Y4M7_HUMAN" 7 1188.6321 1.21 111167 5093 2 1188.630741 595.3233 Treacle protein OS=Homo sapiens OX=9606 GN=TCOF1 PE=1 SV=3 4.68 1478.3 - 418846 - - - -1.1576 - 3.141 0.492 - 754.9 1 2 0 -0.0014 11 0 0 0 4.02E+07 3.32E+07 - - - 5.7707 0.9997 221125_WJC_METTL3_EV_vs_WT_F08.05098.05098.2 8.18E-05 16-Oct R.R[166.11]DNQFDSPK[136.11].R "sp|O14654|IRS4_HUMAN,tr|A0A804CF45|A0A804CF45_HUMAN" 2 1123.5377 1.42 111170 5098 2 1123.536025 562.7761 Insulin receptor substrate 4 OS=Homo sapiens OX=9606 GN=IRS4 PE=1 SV=1 5.96 1478.9 - 2.06E+06 - - - -1.4962 - 1.931 0.454 - 394.6 1 2 0 -0.0017 9 0 0 0 8.90E+07 6.27E+07 - - - 4.2975 0.9648 221125_WJC_METTL3_EV_vs_WT_F08.05099.05099.2 0.428 18-Nov R.LRSEIDNVKK.Q sp|P04264|K2C1_HUMAN 1 1200.6826 999 111171 5099 2 1200.680842 601.3486 "Keratin, type II cytoskeletal 1 OS=Homo sapiens OX=9606 GN=KRT1 PE=1 SV=6" 8.59 1479 - 1.90E+06 - - - -1.4942 - 1.869 0.131 - 279.1 1 2 1 -0.0018 10 0 0 0 3.55E+07 0.00E+00 - - - 1.7537 0.9999 221125_WJC_METTL3_EV_vs_WT_F08.05109.05109.2 5.71E-05 22-Dec R.ESQVVSENGQEK.V sp|Q9P2D1|CHD7_HUMAN 1 1332.6157 0.92 111179 5109 2 1332.614608 667.3151 Chromodomain-helicase-DNA-binding protein 7 OS=Homo sapiens OX=9606 GN=CHD7 PE=1 SV=3 4.25 1480.1 - 2.33E+06 - - - -0.848 - 2.319 0.476 - 389.4 1 2 0 -0.0011 12 0 0 0 4.64E+07 5.03E+07 - - - 4.7696 0.9998 221125_WJC_METTL3_EV_vs_WT_F08.05111.05111.3 0.0125 13/44 K.MIASDSHR[166.11]PEVK[136.11].L "sp|Q9NYF8|BCLF1_HUMAN,tr|E9PKI6|E9PKI6_HUMAN,tr|A0A1W2PQ43|A0A1W2PQ43_HUMAN,tr|E9PK91|E9PK91_HUMAN,tr|E9PJA7|E9PJA7_HUMAN,tr|E9PK09|E9PK09_HUMAN,tr|E9PQN2|E9PQN2_HUMAN" 7 1386.7045 2.13 111181 5111 3 1386.701636 463.2421 Bcl-2-associated transcription factor 1 OS=Homo sapiens OX=9606 GN=BCLAF1 PE=1 SV=2 6.51 1480.2 - 9.28E+06 - - - -2.0322 - 2.6 0.374 - 190.4 1 2 0 -0.0028 12 0 0 0 1.05E+10 4.94E+09 - - - 5.3575 1 221125_WJC_METTL3_EV_vs_WT_F08.05113.05113.2 6.51E-06 26-Dec R.AQAVSEDAGGNEGR[166.11].A "sp|P55884|EIF3B_HUMAN,tr|C9JZG1|C9JZG1_HUMAN" 2 1369.6098 1.27 111183 5113 2 1369.606568 685.8122 Eukaryotic translation initiation factor 3 subunit B OS=Homo sapiens OX=9606 GN=EIF3B PE=1 SV=3 4.14 1480.3 - 1.59E+06 - - - -2.3269 - 2.258 0.638 - 365.8 1 2 0 -0.0032 14 0 0 0 1.99E+08 1.56E+08 - - - 5.7962 0.9236 221125_WJC_METTL3_EV_vs_WT_F08.05116.05116.2 0.000251 14/18 L.ASDSHR[166.11]PEVK[136.11].L "sp|Q9NYF8|BCLF1_HUMAN,tr|E9PKI6|E9PKI6_HUMAN,tr|A0A1W2PQ43|A0A1W2PQ43_HUMAN,tr|E9PK91|E9PK91_HUMAN,tr|E9PJA7|E9PJA7_HUMAN,tr|E9PK09|E9PK09_HUMAN,tr|E9PQN2|E9PQN2_HUMAN" 7 1142.5799 2.48 111186 5116 2 1142.574548 572.2972 Bcl-2-associated transcription factor 1 OS=Homo sapiens OX=9606 GN=BCLAF1 PE=1 SV=2 6.8 1480.7 - 567902 - - - -4.6885 - 2.662 0.502 - 732.5 1 1 0 -0.0054 10 0 0 0 9.30E+08 3.75E+08 - - - 5.48 0.9997 221125_WJC_METTL3_EV_vs_WT_F08.05119.05119.3 3.08E-05 14/32 K.YK[136.11]AEDEVQR[166.11].E "sp|P0DMV8|HS71A_HUMAN,sp|P34931|HS71L_HUMAN,sp|P0DMV9|HS71B_HUMAN,tr|Q53FA3|Q53FA3_HUMAN,tr|V9GZ37|V9GZ37_HUMAN,tr|A0A0G2JIW1|A0A0G2JIW1_HUMAN" 6 1154.5687 0.01 111187 5119 3 1154.567459 385.8635 Heat shock 70 kDa protein 1A OS=Homo sapiens OX=9606 GN=HSPA1A PE=1 SV=1 4.68 1481.1 - 1.03E+08 - - - -1.0506 - 2.67 0.374 - 329.4 1 2 1 -0.0012 9 0 0 0 1.89E+08 2.17E+10 - - - 5.6692 0.9991 221125_WJC_METTL3_EV_vs_WT_F08.05122.05122.2 0.0049 18-Nov R.KIEVNNATAR.V "sp|O43251|RFOX2_HUMAN,sp|Q9NWB1|RFOX1_HUMAN,sp|A6NFN3|RFOX3_HUMAN,tr|A0A6Q8PGE0|A0A6Q8PGE0_HUMAN,tr|A0A6Q8PH77|A0A6Q8PH77_HUMAN,tr|A0A286YEU2|A0A286YEU2_HUMAN,tr|A0A087X2B1|A0A087X2B1_HUMAN,tr|F8VR27|F8VR27_HUMAN,tr|B7Z1U7|B7Z1U7_HUMAN,tr|B0QYV1|B0QYV1_HUMAN,tr|A0A6Q8PHA3|A0A6Q8PHA3_HUMAN,tr|A0A3B3ITL7|A0A3B3ITL7_HUMAN,tr|F8VZY7|F8VZY7_HUMAN,tr|B0QYY4|B0QYY4_HUMAN,tr|J3KNW3|J3KNW3_HUMAN,tr|F8VZG9|F8VZG9_HUMAN,tr|J3QRF4|J3QRF4_HUMAN,tr|F8VRS4|F8VRS4_HUMAN,tr|A0A6Q8PFM4|A0A6Q8PFM4_HUMAN,tr|S4R469|S4R469_HUMAN,tr|A0A804HKG7|A0A804HKG7_HUMAN,tr|A0A0G2JRD1|A0A0G2JRD1_HUMAN,tr|A0A0G2JRA5|A0A0G2JRA5_HUMAN,tr|A0A804HJM2|A0A804HJM2_HUMAN,tr|I3L1D4|I3L1D4_HUMAN,tr|S4R3K7|S4R3K7_HUMAN" 26 1114.6095 1.24 111190 5122 2 1114.607245 558.312 RNA binding protein fox-1 homolog 2 OS=Homo sapiens OX=9606 GN=RBFOX2 PE=1 SV=3 8.75 1481.3 - 3.45E+06 - - - -1.9971 - 2.239 0.267 - 399.4 1 2 0 -0.0022 10 0 0 0 3.59E+09 2.90E+09 - - - 3.2622 0.9952 221125_WJC_METTL3_EV_vs_WT_F08.05123.05123.2 0.00151 20-Sep K.STSTPTSPGPR[166.11].T "sp|Q8WWM7|ATX2L_HUMAN,tr|A0A0C4DGL7|A0A0C4DGL7_HUMAN,tr|H3BUF6|H3BUF6_HUMAN,tr|H3BRB0|H3BRB0_HUMAN" 4 1096.5388 1.42 111191 5123 2 1096.533398 549.2767 Ataxin-2-like protein OS=Homo sapiens OX=9606 GN=ATXN2L PE=1 SV=2 9.47 1481.4 - 2.84E+06 - - - -4.9465 - 1.839 0.414 - 264.1 1 2 0 -0.0054 11 0 0 0 6.08E+07 4.30E+07 - - - 3.7452 0.9122 221125_WJC_METTL3_EV_vs_WT_F08.05124.05124.2 0.00105 18-Aug Q.VHPDTGISSK[136.11].A "sp|Q8N257|H2B3B_HUMAN,sp|P33778|H2B1B_HUMAN,sp|Q96A08|H2B1A_HUMAN,sp|Q5QNW6|H2B2F_HUMAN,sp|P58876|H2B1D_HUMAN,sp|Q99880|H2B1L_HUMAN,sp|P62807|H2B1C_HUMAN,sp|Q99877|H2B1N_HUMAN,sp|P57053|H2BFS_HUMAN,sp|P23527|H2B1O_HUMAN,sp|O60814|H2B1K_HUMAN,sp|Q93079|H2B1H_HUMAN,sp|Q99879|H2B1M_HUMAN,sp|Q16778|H2B2E_HUMAN,sp|P06899|H2B1J_HUMAN,tr|U3KQK0|U3KQK0_HUMAN" 16 1047.544 1.23 111192 5124 2 1047.541058 524.7793 Histone H2B type 3-B OS=Homo sapiens OX=9606 GN=H2BU1 PE=1 SV=3 6.71 1481.5 - 2.61E+06 - - - -2.8314 - 1.542 0.405 - 209.8 1 1 0 -0.003 10 0 0 0 1.24E+07 1.01E+07 - - - 3.2403 0.9997 221125_WJC_METTL3_EV_vs_WT_F08.05125.05125.2 0.0047 13/18 R.K[136.11]IEVNNATAR[166.11].V "sp|O43251|RFOX2_HUMAN,sp|Q9NWB1|RFOX1_HUMAN,sp|A6NFN3|RFOX3_HUMAN,tr|A0A6Q8PGE0|A0A6Q8PGE0_HUMAN,tr|A0A6Q8PH77|A0A6Q8PH77_HUMAN,tr|A0A286YEU2|A0A286YEU2_HUMAN,tr|A0A087X2B1|A0A087X2B1_HUMAN,tr|F8VR27|F8VR27_HUMAN,tr|B7Z1U7|B7Z1U7_HUMAN,tr|B0QYV1|B0QYV1_HUMAN,tr|A0A6Q8PHA3|A0A6Q8PHA3_HUMAN,tr|A0A3B3ITL7|A0A3B3ITL7_HUMAN,tr|F8VZY7|F8VZY7_HUMAN,tr|B0QYY4|B0QYY4_HUMAN,tr|J3KNW3|J3KNW3_HUMAN,tr|F8VZG9|F8VZG9_HUMAN,tr|J3QRF4|J3QRF4_HUMAN,tr|F8VRS4|F8VRS4_HUMAN,tr|A0A6Q8PFM4|A0A6Q8PFM4_HUMAN,tr|S4R469|S4R469_HUMAN,tr|A0A804HKG7|A0A804HKG7_HUMAN,tr|A0A0G2JRD1|A0A0G2JRD1_HUMAN,tr|A0A0G2JRA5|A0A0G2JRA5_HUMAN,tr|A0A804HJM2|A0A804HJM2_HUMAN,tr|I3L1D4|I3L1D4_HUMAN,tr|S4R3K7|S4R3K7_HUMAN" 26 1132.6319 1.24 111193 5125 2 1132.629655 567.3232 RNA binding protein fox-1 homolog 2 OS=Homo sapiens OX=9606 GN=RBFOX2 PE=1 SV=3 8.75 1481.6 - 2.57E+06 - - - -2.0183 - 2.514 0.433 - 596 1 2 0 -0.0023 10 0 0 0 3.59E+09 2.90E+09 - - - 4.8117 0.9989 221125_WJC_METTL3_EV_vs_WT_F08.05128.05128.2 0.00305 13/20 K.VSVQNGSIHQK.D "sp|Q7Z739|YTHD3_HUMAN,tr|S4R373|S4R373_HUMAN" 2 1195.6309 1.49 111196 5128 2 1195.629063 598.8227 YTH domain-containing family protein 3 OS=Homo sapiens OX=9606 GN=YTHDF3 PE=1 SV=1 8.73 1481.9 - 1.47E+06 - - - -1.5657 - 2.126 0.217 - 672.7 1 2 0 -0.0019 11 0 0 0 2.62E+07 1.75E+07 - - - 2.6836 0.9325 221125_WJC_METTL3_EV_vs_WT_F08.05131.05131.3 0.06 Aug-32 K.YKAEDEVQR[166.11].E "sp|P0DMV8|HS71A_HUMAN,sp|P34931|HS71L_HUMAN,sp|P0DMV9|HS71B_HUMAN,tr|Q53FA3|Q53FA3_HUMAN,tr|V9GZ37|V9GZ37_HUMAN,tr|A0A0G2JIW1|A0A0G2JIW1_HUMAN" 6 1146.5545 - 111197 5131 3 1146.553259 383.1921 Heat shock 70 kDa protein 1A OS=Homo sapiens OX=9606 GN=HSPA1A PE=1 SV=1 4.68 1482.3 - 8.56E+06 - - - -1.058 - 1.319 0.196 - 94.9 1 2 1 -0.0012 9 0 0 0 - - - - - 1.5593 0.9793 221125_WJC_METTL3_EV_vs_WT_F08.05132.05132.2 7.21E-06 14-Nov Y.K[136.11]AEDEVQR[166.11].E "sp|P0DMV8|HS71A_HUMAN,sp|P34931|HS71L_HUMAN,sp|P0DMV9|HS71B_HUMAN,tr|Q53FA3|Q53FA3_HUMAN,tr|V9GZ37|V9GZ37_HUMAN,tr|A0A0G2JIW1|A0A0G2JIW1_HUMAN" 6 991.5053 0.34 111198 5132 2 991.503337 496.7599 Heat shock 70 kDa protein 1A OS=Homo sapiens OX=9606 GN=HSPA1A PE=1 SV=1 4.68 1482.3 - 7.21E+06 - - - -2.0232 - 2.196 0.404 - 450.3 1 1 0 -0.002 8 0 0 0 9.03E+07 2.68E+08 - - - 4.3968 1 221125_WJC_METTL3_EV_vs_WT_F08.05135.05135.2 9.29E-05 16/24 K.AAATPESQEPQAK.G sp|P49006|MRP_HUMAN 1 1326.6416 0.92 111201 5135 2 1326.63931 664.3281 MARCKS-related protein OS=Homo sapiens OX=9606 GN=MARCKSL1 PE=1 SV=2 4.53 1482.5 - 4.78E+06 - - - -1.6953 - 2.835 0.621 - 922.7 1 2 0 -0.0022 13 0 0 0 4.23E+08 4.61E+08 - - - 6.3014 0.9998 221125_WJC_METTL3_EV_vs_WT_F08.05136.05136.2 7.47E-06 16/22 K.MIASDSHR[166.11]PEVK[136.11].L "sp|Q9NYF8|BCLF1_HUMAN,tr|E9PKI6|E9PKI6_HUMAN,tr|A0A1W2PQ43|A0A1W2PQ43_HUMAN,tr|E9PK91|E9PK91_HUMAN,tr|E9PJA7|E9PJA7_HUMAN,tr|E9PK09|E9PK09_HUMAN,tr|E9PQN2|E9PQN2_HUMAN" 7 1386.7045 2.2 111202 5136 2 1386.701762 694.3595 Bcl-2-associated transcription factor 1 OS=Homo sapiens OX=9606 GN=BCLAF1 PE=1 SV=2 6.51 1482.6 - 2.26E+06 - - - -1.9413 - 2.645 0.555 - 568.7 1 2 0 -0.0027 12 0 0 0 9.68E+08 4.40E+08 - - - 5.6986 0.9973 221125_WJC_METTL3_EV_vs_WT_F08.05137.05137.2 0.053 20-Oct K.QK[136.11]PITPETAEK[136.11].L "sp|P60953|CDC42_HUMAN,tr|A0A590UJK8|A0A590UJK8_HUMAN" 2 1256.6947 3.66 111203 5137 2 1256.695434 629.3546 Cell division control protein 42 homolog OS=Homo sapiens OX=9606 GN=CDC42 PE=1 SV=2 6.14 1482.7 - 948896 - - - 0.5705 - 1.22 0.278 - 166.9 1 2 0 0.0007 11 0 0 0 5.43E+07 1.48E+07 - - - 1.632 0.9998 221125_WJC_METTL3_EV_vs_WT_F08.05141.05141.2 0.000574 24-Dec K.AAATPESQEPQAK[136.11].G sp|P49006|MRP_HUMAN 1 1334.6558 0.92 111205 5141 2 1334.653533 668.3352 MARCKS-related protein OS=Homo sapiens OX=9606 GN=MARCKSL1 PE=1 SV=2 4.53 1483.2 - 1.22E+07 - - - -1.6678 - 2.34 0.53 - 562.5 1 2 0 -0.0022 13 0 0 0 4.23E+08 4.61E+08 - - - 5.1368 0.9554 221125_WJC_METTL3_EV_vs_WT_F08.05143.05143.3 0.00246 Oct-40 K.VSVQNGSIHQK.D "sp|Q7Z739|YTHD3_HUMAN,tr|S4R373|S4R373_HUMAN" 2 1195.6309 1.38 111207 5143 3 1195.628392 399.5509 YTH domain-containing family protein 3 OS=Homo sapiens OX=9606 GN=YTHDF3 PE=1 SV=1 8.73 1483.2 - 1.33E+07 - - - -2.1269 - 1.921 0.082 - 118.4 1 2 0 -0.0025 11 0 0 0 1.30E+08 9.43E+07 - - - 1.3081 0.9838 221125_WJC_METTL3_EV_vs_WT_F08.05145.05145.2 0.418 12-Jul K.AEDEVQR[166.11].E "sp|P0DMV8|HS71A_HUMAN,sp|P34931|HS71L_HUMAN,sp|P0DMV9|HS71B_HUMAN,tr|Q53FA3|Q53FA3_HUMAN,tr|V9GZ37|V9GZ37_HUMAN,tr|A0A0G2JIW1|A0A0G2JIW1_HUMAN" 6 855.3962 0.03 111209 5145 2 855.393572 428.7054 Heat shock 70 kDa protein 1A OS=Homo sapiens OX=9606 GN=HSPA1A PE=1 SV=1 4.14 1483.4 - 5.24E+06 - - - -3.0489 - 1.306 0.199 - 140.4 1 2 0 -0.0026 7 0 0 0 1.05E+06 3.13E+07 - - - 1.3559 0.9996 221125_WJC_METTL3_EV_vs_WT_F08.05150.05150.2 3.59E-06 13/22 K.MIASDSHRPEVK.L "sp|Q9NYF8|BCLF1_HUMAN,tr|E9PKI6|E9PKI6_HUMAN,tr|A0A1W2PQ43|A0A1W2PQ43_HUMAN,tr|E9PK91|E9PK91_HUMAN,tr|E9PJA7|E9PJA7_HUMAN,tr|E9PK09|E9PK09_HUMAN,tr|E9PQN2|E9PQN2_HUMAN" 7 1368.682 2.2 111212 5150 2 1368.67964 685.3483 Bcl-2-associated transcription factor 1 OS=Homo sapiens OX=9606 GN=BCLAF1 PE=1 SV=2 6.51 1483.9 - 1.77E+07 - - - -1.7126 - 2.164 0.393 - 390.1 1 2 0 -0.0023 12 0 0 0 9.68E+08 4.40E+08 - - - 3.9741 0.998 221125_WJC_METTL3_EV_vs_WT_F08.05159.05159.2 9.26E-06 15/20 R.KLSSETYSQAK.D sp|Q08J23|NSUN2_HUMAN 1 1240.6299 0.39 111219 5159 2 1240.623817 621.3222 RNA cytosine C(5)-methyltransferase NSUN2 OS=Homo sapiens OX=9606 GN=NSUN2 PE=1 SV=2 8.5 1484.7 - 4.12E+06 - - - -4.9289 - 2.366 0.498 - 514.6 1 2 0 -0.0061 11 0 0 0 2.76E+07 6.99E+07 - - - 5.0471 0.994 221125_WJC_METTL3_EV_vs_WT_F08.05161.05161.3 0.019 Oct-44 R.NSPGSQVASNPR[166.11].Q sp|Q9H0D6|XRN2_HUMAN 1 1222.593 0.46 111221 5161 3 1222.589076 408.5383 5'-3' exoribonuclease 2 OS=Homo sapiens OX=9606 GN=XRN2 PE=1 SV=1 9.75 1484.9 - 2.59E+06 - - - -3.1957 - 1.712 0.273 - 107.5 1 2 0 -0.0039 12 0 0 0 2.95E+07 6.49E+07 - - - 3.0729 0.9997 221125_WJC_METTL3_EV_vs_WT_F08.05165.05165.2 0.000131 14-Nov K.HEISEMNR.M "sp|P13647|K2C5_HUMAN,tr|H0YI76|H0YI76_HUMAN" 2 1014.4553 258.79 111223 5165 2 1014.45308 508.2349 "Keratin, type II cytoskeletal 5 OS=Homo sapiens OX=9606 GN=KRT5 PE=1 SV=3" 5.4 1485.4 - 8.92E+06 - - - -2.1667 - 1.789 0.528 - 399.1 1 2 0 -0.0022 8 0 0 0 1.19E+08 4.59E+05 - - - 4.6944 0.9878 221125_WJC_METTL3_EV_vs_WT_F08.05166.05166.2 1.05E-06 15/20 M.IASDSHRPEVK.L "sp|Q9NYF8|BCLF1_HUMAN,tr|E9PKI6|E9PKI6_HUMAN,tr|A0A1W2PQ43|A0A1W2PQ43_HUMAN,tr|E9PK91|E9PK91_HUMAN,tr|E9PJA7|E9PJA7_HUMAN,tr|E9PK09|E9PK09_HUMAN,tr|E9PQN2|E9PQN2_HUMAN" 7 1237.6415 2.81 111224 5166 2 1237.638869 619.828 Bcl-2-associated transcription factor 1 OS=Homo sapiens OX=9606 GN=BCLAF1 PE=1 SV=2 6.75 1485.5 - 4.50E+06 - - - -2.125 - 2.856 0.497 - 773 1 1 0 -0.0026 11 0 0 0 1.82E+08 6.49E+07 - - - 5.55 0.9722 221125_WJC_METTL3_EV_vs_WT_F08.05172.05172.3 0.00525 Nov-40 M.IASDSHRPEVK.L "sp|Q9NYF8|BCLF1_HUMAN,tr|E9PKI6|E9PKI6_HUMAN,tr|A0A1W2PQ43|A0A1W2PQ43_HUMAN,tr|E9PK91|E9PK91_HUMAN,tr|E9PJA7|E9PJA7_HUMAN,tr|E9PK09|E9PK09_HUMAN,tr|E9PQN2|E9PQN2_HUMAN" 7 1237.6415 2.09 111228 5172 3 1237.638418 413.5544 Bcl-2-associated transcription factor 1 OS=Homo sapiens OX=9606 GN=BCLAF1 PE=1 SV=2 6.75 1486.1 - 4.11E+07 - - - -2.4894 - 2.363 0.373 - 112 1 1 0 -0.0031 11 0 0 0 8.56E+08 4.10E+08 - - - 5.1406 0.899 221125_WJC_METTL3_EV_vs_WT_F08.05173.05173.2 0.00513 20-Sep M.IASDSHR[166.11]PEVK[136.11].L "sp|Q9NYF8|BCLF1_HUMAN,tr|E9PKI6|E9PKI6_HUMAN,tr|A0A1W2PQ43|A0A1W2PQ43_HUMAN,tr|E9PK91|E9PK91_HUMAN,tr|E9PJA7|E9PJA7_HUMAN,tr|E9PK09|E9PK09_HUMAN,tr|E9PQN2|E9PQN2_HUMAN" 7 1255.664 2.81 111229 5173 2 1255.658793 628.8393 Bcl-2-associated transcription factor 1 OS=Homo sapiens OX=9606 GN=BCLAF1 PE=1 SV=2 6.75 1486.2 - 4.98E+06 - - - -4.1221 - 2.177 0.414 - 175.5 1 1 0 -0.0052 11 0 0 0 1.82E+08 6.49E+07 - - - 4.2017 0.9995 221125_WJC_METTL3_EV_vs_WT_F08.05174.05174.3 0.000611 13/44 K.MIASDSHR[166.11]PEVK.L "sp|Q9NYF8|BCLF1_HUMAN,tr|E9PKI6|E9PKI6_HUMAN,tr|A0A1W2PQ43|A0A1W2PQ43_HUMAN,tr|E9PK91|E9PK91_HUMAN,tr|E9PJA7|E9PJA7_HUMAN,tr|E9PK09|E9PK09_HUMAN,tr|E9PQN2|E9PQN2_HUMAN" 7 1378.6903 - 111230 5174 3 1378.69006 460.5707 Bcl-2-associated transcription factor 1 OS=Homo sapiens OX=9606 GN=BCLAF1 PE=1 SV=2 6.51 1486.2 - 4.88E+06 - - - -0.1407 - 2.116 0.288 - 160 1 2 0 -0.0002 12 0 0 0 - - - - - 3.8284 0.9613 221125_WJC_METTL3_EV_vs_WT_F08.05183.05183.3 0.0773 Oct-36 L.ASDSHR[166.11]PEVK[136.11].L "sp|Q9NYF8|BCLF1_HUMAN,tr|E9PKI6|E9PKI6_HUMAN,tr|A0A1W2PQ43|A0A1W2PQ43_HUMAN,tr|E9PK91|E9PK91_HUMAN,tr|E9PJA7|E9PJA7_HUMAN,tr|E9PK09|E9PK09_HUMAN,tr|E9PQN2|E9PQN2_HUMAN" 7 1142.5799 0.001 111236 5183 3 1142.578218 381.8672 Bcl-2-associated transcription factor 1 OS=Homo sapiens OX=9606 GN=BCLAF1 PE=1 SV=2 6.8 1487.2 - 2.48E+07 - - - -1.4765 - 2.037 0.324 - 193.5 1 1 0 -0.0017 10 0 0 0 0.00E+00 2.37E+08 - - - 4.2296 1 221125_WJC_METTL3_EV_vs_WT_F08.05190.05190.2 3.05E-10 19/30 R.PASASPAPNANADGTK.T "sp|Q6W2J9|BCOR_HUMAN,tr|H7BZ37|H7BZ37_HUMAN,tr|H7C2V9|H7C2V9_HUMAN,tr|H7BYY2|H7BYY2_HUMAN,tr|H7C231|H7C231_HUMAN" 5 1467.6954 2.73 111242 5190 2 1467.692547 734.855 BCL-6 corepressor OS=Homo sapiens OX=9606 GN=BCOR PE=1 SV=1 6.26 1487.9 - 2.12E+06 - - - -1.9343 - 3.493 0.624 - 1193.2 1 1 0 -0.0028 16 0 0 0 2.05E+07 7.52E+06 - - - 6.724 0.9998 221125_WJC_METTL3_EV_vs_WT_F08.05193.05193.2 5.06E-06 22-Oct R.NSPGSQVASNPR.Q sp|Q9H0D6|XRN2_HUMAN 1 1212.5847 1.16 111244 5193 2 1212.582633 607.2996 5'-3' exoribonuclease 2 OS=Homo sapiens OX=9606 GN=XRN2 PE=1 SV=1 9.75 1488.2 - 8.29E+06 - - - -1.7153 - 2.03 0.593 - 373.8 1 2 0 -0.0021 12 0 0 0 8.30E+08 7.15E+08 - - - 5.2832 0.9999 221125_WJC_METTL3_EV_vs_WT_F08.05197.05197.3 6.89E-07 15/60 K.APEGGEGAQPVPGHAR[166.11].K "sp|Q6W2J9|BCOR_HUMAN,tr|H7BZ37|H7BZ37_HUMAN,tr|H7C2V9|H7C2V9_HUMAN,tr|H7BYY2|H7BYY2_HUMAN,tr|H7C231|H7C231_HUMAN" 5 1538.7465 2.03 111247 5197 3 1538.743843 513.9228 BCL-6 corepressor OS=Homo sapiens OX=9606 GN=BCOR PE=1 SV=1 5.4 1488.6 - 2.25E+06 - - - -1.7417 - 2.522 0.477 - 186.2 1 2 0 -0.0027 16 0 0 0 3.79E+07 1.87E+07 - - - 6.2309 0.9997 221125_WJC_METTL3_EV_vs_WT_F08.05198.05198.2 0.000605 20-Dec R.QC[160.03]QQNLDAASK[136.11].R "sp|Q9Y6D9|MD1L1_HUMAN,tr|C9JJ38|C9JJ38_HUMAN,tr|C9JIR0|C9JIR0_HUMAN" 3 1269.5863 1.75 111248 5198 2 1269.58308 635.8004 Mitotic spindle assembly checkpoint protein MAD1 OS=Homo sapiens OX=9606 GN=MAD1L1 PE=1 SV=2 5.83 1488.8 - 2.06E+06 - - - -2.5355 - 2.529 0.487 - 723.6 1 2 0 -0.0032 11 0 0 0 3.75E+07 2.14E+07 - - - 5.147 1 221125_WJC_METTL3_EV_vs_WT_F08.05201.05201.2 1.01E-06 18/30 R.PASASPAPNANADGTK[136.11].T "sp|Q6W2J9|BCOR_HUMAN,tr|H7BZ37|H7BZ37_HUMAN,tr|H7C2V9|H7C2V9_HUMAN,tr|H7BYY2|H7BYY2_HUMAN,tr|H7C231|H7C231_HUMAN" 5 1475.7096 2.73 111251 5201 2 1475.707758 738.8621 BCL-6 corepressor OS=Homo sapiens OX=9606 GN=BCOR PE=1 SV=1 6.26 1489.1 - 1.21E+06 - - - -1.2387 - 3.411 0.675 - 1118.1 1 1 0 -0.0018 16 0 0 0 2.05E+07 7.52E+06 - - - 7.0426 0.9998 221125_WJC_METTL3_EV_vs_WT_F08.05204.05204.3 8.91E-06 13/36 K.ISEKEEVTTR.E sp|Q03252|LMNB2_HUMAN 1 1190.6143 1.13 111253 5204 3 1190.611665 397.8787 Lamin-B2 OS=Homo sapiens OX=9606 GN=LMNB2 PE=1 SV=4 4.79 1489.4 - 1.05E+07 - - - -2.198 - 2.639 0.523 - 224.6 1 2 1 -0.0026 10 0 0 0 4.93E+07 4.35E+07 - - - 7.2042 0.9893 221125_WJC_METTL3_EV_vs_WT_F08.05206.05206.3 0.00412 Aug-44 R.NPPPNSDPNLRR.F sp|Q96I24|FUBP3_HUMAN 1 1375.6957 4.03 111254 5206 3 1375.690731 459.5725 Far upstream element-binding protein 3 OS=Homo sapiens OX=9606 GN=FUBP3 PE=1 SV=2 9.6 1489.6 - 2.68E+07 - - - -3.5829 - 1.53 0.283 - 67.5 1 2 0 -0.0049 12 0 0 0 2.98E+09 7.40E+08 - - - 2.8726 0.9998 221125_WJC_METTL3_EV_vs_WT_F08.05207.05207.2 0.000188 18-Nov R.SFHPEQDAGK.V "sp|Q9BV38|WDR18_HUMAN,tr|U3KQC1|U3KQC1_HUMAN,tr|A0A0A0MQU0|A0A0A0MQU0_HUMAN,tr|K7EML4|K7EML4_HUMAN,tr|K7EIR0|K7EIR0_HUMAN" 5 1114.5043 1.82 111255 5207 2 1114.503337 558.2594 WD repeat-containing protein 18 OS=Homo sapiens OX=9606 GN=WDR18 PE=1 SV=2 5.3 1489.7 - 8.72E+06 - - - -0.8973 - 1.959 0.472 - 315.2 1 2 0 -0.001 10 0 0 0 6.95E+07 3.83E+07 - - - 4.4038 0.9999 221125_WJC_METTL3_EV_vs_WT_F08.05209.05209.3 0.000298 Dec-36 R.FNSSDHIESK.G sp|Q96HR8|NAF1_HUMAN 1 1162.5255 0.71 111257 5209 3 1162.524017 388.5158 H\ACA ribonucleoprotein complex non-core subunit NAF1 OS=Homo sapiens OX=9606 GN=NAF1 PE=1 SV=2 5.32 1489.7 - 6.76E+06 - - - -1.2473 - 2.52 0.354 - 126.8 1 2 0 -0.0014 10 0 0 0 8.09E+07 1.13E+08 - - - 5.1856 1 221125_WJC_METTL3_EV_vs_WT_F08.05211.05211.3 1.67E-08 16/60 K.APEGGEGAQPVPGHAR.K "sp|Q6W2J9|BCOR_HUMAN,tr|H7BZ37|H7BZ37_HUMAN,tr|H7C2V9|H7C2V9_HUMAN,tr|H7BYY2|H7BYY2_HUMAN,tr|H7C231|H7C231_HUMAN" 5 1528.7383 2.03 111259 5211 3 1528.736398 510.5867 BCL-6 corepressor OS=Homo sapiens OX=9606 GN=BCOR PE=1 SV=1 5.4 1489.8 - 4.84E+06 - - - -1.2134 - 2.929 0.604 - 220.8 1 2 0 -0.0019 16 0 0 0 3.79E+07 1.87E+07 - - - 8.0309 0.9995 221125_WJC_METTL3_EV_vs_WT_F08.05213.05213.2 0.000697 16/18 K.R[166.11]FDAQTGADR[166.11].E sp|P43686|PRS6B_HUMAN 1 1155.5536 -1 111261 5213 2 1155.550475 578.7841 26S proteasome regulatory subunit 6B OS=Homo sapiens OX=9606 GN=PSMC4 PE=1 SV=2 5.96 1490 - 2.33E+06 - - - -2.6818 - 2.788 0.386 - 622.4 1 2 0 -0.0031 10 0 0 0 0.00E+00 0.00E+00 - - - 4.753 0.9999 221125_WJC_METTL3_EV_vs_WT_F08.05215.05215.2 4.86E-05 18-Nov R.FNSSDHIESK.G sp|Q96HR8|NAF1_HUMAN 1 1162.5255 1.6 111263 5215 2 1162.523975 582.27 H\ACA ribonucleoprotein complex non-core subunit NAF1 OS=Homo sapiens OX=9606 GN=NAF1 PE=1 SV=2 5.32 1490.2 - 1.23E+06 - - - -1.2834 - 2.196 0.553 - 243.2 1 2 0 -0.0015 10 0 0 0 7.45E+06 4.67E+06 - - - 5.3207 0.9923 221125_WJC_METTL3_EV_vs_WT_F08.05218.05218.2 0.00162 18-Nov R.FNSSDHIESK[136.11].G sp|Q96HR8|NAF1_HUMAN 1 1170.5397 -1 111266 5218 2 1170.531563 586.2771 H\ACA ribonucleoprotein complex non-core subunit NAF1 OS=Homo sapiens OX=9606 GN=NAF1 PE=1 SV=2 5.32 1490.6 - 554902 - - - -6.9233 - 2.276 0.506 - 225 1 2 0 -0.0081 10 0 0 0 0.00E+00 0.00E+00 - - - 5.0714 0.9995 221125_WJC_METTL3_EV_vs_WT_F08.05221.05221.2 0.0842 14/18 R.LHDIETENQK.L "sp|Q13948|CASP_HUMAN,sp|P39880|CUX1_HUMAN,tr|A0A2R8Y852|A0A2R8Y852_HUMAN,tr|A0A2R8YDI1|A0A2R8YDI1_HUMAN" 4 1225.5939 5.47 111268 5221 2 1225.592005 613.8042 Protein CASP OS=Homo sapiens OX=9606 GN=CUX1 PE=1 SV=2 4.65 1490.8 - 3.54E+06 - - - -1.5307 - 2.441 0.27 - 813.1 1 2 0 -0.0019 10 0 0 0 7.38E+07 1.35E+07 - - - 3.5256 0.9985 221125_WJC_METTL3_EV_vs_WT_F08.05222.05222.2 4.40E-06 18-Dec K.ISEKEEVTTR.E sp|Q03252|LMNB2_HUMAN 1 1190.6143 1.45 111269 5222 2 1190.615137 596.3144 Lamin-B2 OS=Homo sapiens OX=9606 GN=LMNB2 PE=1 SV=4 4.79 1490.9 - 602304 - - - 0.7181 - 2.134 0.507 - 594.3 1 2 1 0.0009 10 0 0 0 9.76E+06 6.73E+06 - - - 4.9012 0.9991 221125_WJC_METTL3_EV_vs_WT_F08.05223.05223.3 0.0121 Aug-44 R.NPPPNSDPNLR[166.11]R[166.11].F sp|Q96I24|FUBP3_HUMAN 1 1395.7122 3.99 111270 5223 3 1395.710819 466.2447 Far upstream element-binding protein 3 OS=Homo sapiens OX=9606 GN=FUBP3 PE=1 SV=2 9.6 1491 - 3.07E+07 - - - -0.9895 - 1.533 0.331 - 82.6 1 2 0 -0.0014 12 0 0 0 3.00E+09 7.53E+08 - - - 3.4141 0.9987 221125_WJC_METTL3_EV_vs_WT_F08.05225.05225.2 3.43E-05 14-Sep K.MYEEHLK[136.11]R[166.11].M "sp|P84090|ERH_HUMAN,tr|G3V279|G3V279_HUMAN" 2 1122.5611 2.36 111272 5225 2 1122.560348 562.2878 Enhancer of rudimentary homolog OS=Homo sapiens OX=9606 GN=ERH PE=1 SV=1 6.51 1491.1 - 2.02E+07 - - - -0.6556 - 1.801 0.185 - 355.9 1 2 0 -0.0007 8 0 0 0 5.00E+08 2.12E+08 - - - 2.1816 1 221125_WJC_METTL3_EV_vs_WT_F08.05230.05230.3 1.45E-05 16/48 K.VGGTSDVEVNEKK.D "sp|P10809|CH60_HUMAN,tr|A0A7I2V2X6|A0A7I2V2X6_HUMAN,tr|A0A7I2YQK6|A0A7I2YQK6_HUMAN,tr|A0A7I2V599|A0A7I2V599_HUMAN" 4 1360.6834 1.1 111277 5230 3 1360.682789 454.5684 "60 kDa heat shock protein, mitochondrial OS=Homo sapiens OX=9606 GN=HSPD1 PE=1 SV=2" 4.68 1491.3 - 5.79E+06 - - - -0.4667 - 2.845 0.494 - 459.4 1 2 0 -0.0006 13 0 0 0 5.51E+09 4.99E+09 - - - 6.8823 0.9999 221125_WJC_METTL3_EV_vs_WT_F08.05232.05232.3 1.98E-07 17/56 R.AVGPTAEADKSAAEK.R "sp|Q13123|RED_HUMAN,tr|D6REL4|D6REL4_HUMAN,tr|E7EQZ7|E7EQZ7_HUMAN" 3 1443.7205 -1 111279 5232 3 1443.718703 482.2475 Protein Red OS=Homo sapiens OX=9606 GN=IK PE=1 SV=3 4.68 1491.3 - 4.13E+06 - - - -1.271 - 3.461 0.572 - 290.8 1 2 1 -0.0018 15 0 0 0 0.00E+00 0.00E+00 - - - 8.1564 0.9999 221125_WJC_METTL3_EV_vs_WT_F08.05233.05233.2 1.25E-05 14/16 R.HLSDSINQK.H sp|Q9Y4W6|AFG32_HUMAN 1 1040.5251 1.56 111280 5233 2 1040.524071 521.2698 AFG3-like protein 2 OS=Homo sapiens OX=9606 GN=AFG3L2 PE=1 SV=2 6.74 1491.4 - 3.78E+06 - - - -0.963 - 2.271 0.499 - 522.9 1 2 0 -0.001 9 0 0 0 2.23E+07 1.43E+07 - - - 5.0992 0.9998 221125_WJC_METTL3_EV_vs_WT_F08.05235.05235.2 7.69E-06 22-Oct R.SNVQPTAAPGQK[136.11].V "sp|Q96GD4|AURKB_HUMAN,tr|J3QR41|J3QR41_HUMAN,tr|J3KRJ2|J3KRJ2_HUMAN,tr|J3QLN8|J3QLN8_HUMAN,tr|J3KRF8|J3KRF8_HUMAN,tr|J3KTD6|J3KTD6_HUMAN" 6 1204.6291 -1 111282 5235 2 1204.628324 603.3219 Aurora kinase B OS=Homo sapiens OX=9606 GN=AURKB PE=1 SV=3 8.47 1491.5 - 3.31E+06 - - - -0.6857 - 1.968 0.511 - 291.8 1 2 0 -0.0008 12 0 0 0 0.00E+00 0.00E+00 - - - 4.5963 1 221125_WJC_METTL3_EV_vs_WT_F08.05236.05236.2 2.58E-09 13/20 R.VC[160.03]DC[160.03]STPSEC[160.03]R.M sp|Q08554|DSC1_HUMAN 1 1369.5061 999 111283 5236 2 1369.504972 685.7603 Desmocollin-1 OS=Homo sapiens OX=9606 GN=DSC1 PE=1 SV=2 4.37 1491.6 - 3.28E+06 - - - -0.8025 - 2.561 0.728 - 745.1 1 2 0 -0.0011 11 0 0 0 1.30E+07 0.00E+00 - - - 6.9617 0.9996 221125_WJC_METTL3_EV_vs_WT_F08.05237.05237.2 0.0021 18-Dec K.RFDAQTGADR.E sp|P43686|PRS6B_HUMAN 1 1135.537 67.04 111284 5237 2 1135.535446 568.7758 26S proteasome regulatory subunit 6B OS=Homo sapiens OX=9606 GN=PSMC4 PE=1 SV=2 5.96 1491.6 - 2.24E+06 - - - -1.3985 - 2.086 0.37 - 268.7 1 2 0 -0.0016 10 0 0 0 6.48E+08 9.67E+06 - - - 3.8256 0.9844 221125_WJC_METTL3_EV_vs_WT_F08.05238.05238.2 0.00776 18-Sep R.LHDIETENQK[136.11].L "sp|Q13948|CASP_HUMAN,sp|P39880|CUX1_HUMAN,tr|A0A2R8Y852|A0A2R8Y852_HUMAN,tr|A0A2R8YDI1|A0A2R8YDI1_HUMAN" 4 1233.6081 6.08 111285 5238 2 1233.602505 617.8113 Protein CASP OS=Homo sapiens OX=9606 GN=CUX1 PE=1 SV=2 4.65 1491.7 - 2.04E+06 - - - -4.5201 - 1.92 0.205 - 270.5 2 2 0 -0.0056 10 0 0 0 6.53E+07 1.08E+07 - - - 2.2397 1 221125_WJC_METTL3_EV_vs_WT_F08.05239.05239.3 4.08E-05 15/36 R.ESGAHC[160.03]PLC[160.03]R[166.11].G "sp|Q8WVD3|RN138_HUMAN,tr|J3QKM8|J3QKM8_HUMAN,tr|J3KSI2|J3KSI2_HUMAN,tr|J3KRU4|J3KRU4_HUMAN" 4 1195.5102 1.51 111286 5239 3 1195.508446 399.5107 E3 ubiquitin-protein ligase RNF138 OS=Homo sapiens OX=9606 GN=RNF138 PE=1 SV=1 6.82 1491.8 - 1.98E+06 - - - -1.4521 - 2.645 0.496 - 407 1 2 0 -0.0017 10 0 0 0 1.08E+08 7.13E+07 - - - 6.9101 0.999 221125_WJC_METTL3_EV_vs_WT_F08.05247.05247.2 0.0244 14-Aug K.YEDEINKR.T "sp|P48668|K2C6C_HUMAN,sp|P05787|K2C8_HUMAN,sp|Q01546|K22O_HUMAN,sp|Q7Z794|K2C1B_HUMAN,sp|P12035|K2C3_HUMAN,sp|P04264|K2C1_HUMAN,sp|P04259|K2C6B_HUMAN,sp|P13647|K2C5_HUMAN,sp|P35908|K22E_HUMAN,sp|O95678|K2C75_HUMAN,sp|P02538|K2C6A_HUMAN,tr|F8VUG2|F8VUG2_HUMAN,tr|F8W0C6|F8W0C6_HUMAN,tr|F8VP67|F8VP67_HUMAN,tr|F8W1U3|F8W1U3_HUMAN,tr|H0YIN9|H0YIN9_HUMAN" 16 1065.5091 0.35 111293 5247 2 1065.507949 533.7618 "Keratin, type II cytoskeletal 6C OS=Homo sapiens OX=9606 GN=KRT6C PE=1 SV=3" 4.68 1492.3 - 6.46E+06 - - - -1.069 - 1.617 0.278 - 186.6 1 2 0 -0.0011 8 0 0 0 6.87E+07 1.94E+08 - - - 2.5433 1 221125_WJC_METTL3_EV_vs_WT_F08.05248.05248.2 8.18E-05 14/24 K.VGGTSDVEVNEKK.D "sp|P10809|CH60_HUMAN,tr|A0A7I2V2X6|A0A7I2V2X6_HUMAN,tr|A0A7I2YQK6|A0A7I2YQK6_HUMAN,tr|A0A7I2V599|A0A7I2V599_HUMAN" 4 1360.6834 1.16 111294 5248 2 1360.682656 681.349 "60 kDa heat shock protein, mitochondrial OS=Homo sapiens OX=9606 GN=HSPD1 PE=1 SV=2" 4.68 1492.4 - 5.55E+06 - - - -0.5644 - 3.01 0.522 - 451.2 1 2 0 -0.0008 13 0 0 0 6.38E+08 5.51E+08 - - - 5.7244 0.9992 221125_WJC_METTL3_EV_vs_WT_F08.05250.05250.2 0.00212 18-Sep R.ESGAHC[160.03]PLC[160.03]R.G "sp|Q8WVD3|RN138_HUMAN,tr|J3QKM8|J3QKM8_HUMAN,tr|J3KSI2|J3KSI2_HUMAN,tr|J3KRU4|J3KRU4_HUMAN" 4 1185.5019 1.6 111296 5250 2 1185.499784 593.7582 E3 ubiquitin-protein ligase RNF138 OS=Homo sapiens OX=9606 GN=RNF138 PE=1 SV=1 6.82 1492.6 - 2.20E+06 - - - -1.795 - 1.655 0.365 - 284.6 1 2 0 -0.0021 10 0 0 0 2.65E+07 1.66E+07 - - - 3.1425 0.9988 221125_WJC_METTL3_EV_vs_WT_F08.05251.05251.2 0.0818 22-Sep R.NPPPNSDPNLR[166.11]R[166.11].F sp|Q96I24|FUBP3_HUMAN 1 1395.7122 10.14 111297 5251 2 1395.711982 698.8634 Far upstream element-binding protein 3 OS=Homo sapiens OX=9606 GN=FUBP3 PE=1 SV=2 9.6 1492.7 - 2.17E+06 - - - -0.1562 - 1.666 0.25 - 196.9 1 2 0 -0.0002 12 0 0 0 3.61E+08 3.56E+07 - - - 2.2304 0.9997 221125_WJC_METTL3_EV_vs_WT_F08.05256.05256.2 0.00518 18-Dec R.HGSNIEAMSK[136.11].L sp|Q9BWD1|THIC_HUMAN 1 1080.5113 4.19 111302 5256 2 1080.509901 541.2629 "Acetyl-CoA acetyltransferase, cytosolic OS=Homo sapiens OX=9606 GN=ACAT2 PE=1 SV=2" 6.75 1493.1 - 1.26E+06 - - - -1.3346 - 2.516 0.307 - 304.4 1 2 0 -0.0014 10 0 0 0 1.69E+07 4.03E+06 - - - 3.8835 1 221125_WJC_METTL3_EV_vs_WT_F08.05260.05260.2 2.80E-07 17/28 R.AVGPTAEADK[136.11]SAAEK[136.11].R "sp|Q13123|RED_HUMAN,tr|D6REL4|D6REL4_HUMAN,tr|E7EQZ7|E7EQZ7_HUMAN" 3 1459.7489 1 111306 5260 2 1459.744915 730.8817 Protein Red OS=Homo sapiens OX=9606 GN=IK PE=1 SV=3 4.68 1493.6 - 510119 - - - -2.756 - 3.504 0.557 - 888 1 2 1 -0.004 15 0 0 0 4.71E+06 4.73E+06 - - - 6.2365 0.9997 221125_WJC_METTL3_EV_vs_WT_F08.05263.05263.3 0.135 Aug-36 R.ESGAHC[160.03]PLC[160.03]R.G "sp|Q8WVD3|RN138_HUMAN,tr|J3QKM8|J3QKM8_HUMAN,tr|J3KSI2|J3KSI2_HUMAN,tr|J3KRU4|J3KRU4_HUMAN" 4 1185.5019 1.52 111307 5263 3 1185.499628 396.1746 E3 ubiquitin-protein ligase RNF138 OS=Homo sapiens OX=9606 GN=RNF138 PE=1 SV=1 6.82 1494 - 1.58E+07 - - - -1.9266 - 1.725 0.4 - 115.6 1 2 0 -0.0023 10 0 0 0 1.08E+08 7.08E+07 - - - 4.5913 0.9895 221125_WJC_METTL3_EV_vs_WT_F08.05265.05265.2 8.71E-09 15/22 V.GGTSDVEVNEKK.D "sp|P10809|CH60_HUMAN,tr|A0A7I2V2X6|A0A7I2V2X6_HUMAN,tr|A0A7I2YQK6|A0A7I2YQK6_HUMAN,tr|A0A7I2V599|A0A7I2V599_HUMAN" 4 1261.615 1.37 111309 5265 2 1261.613401 631.8148 "60 kDa heat shock protein, mitochondrial OS=Homo sapiens OX=9606 GN=HSPD1 PE=1 SV=2" 4.68 1494.1 - 1.73E+07 - - - -1.2753 - 2.761 0.41 - 1167.9 1 1 0 -0.0016 12 0 0 0 2.08E+08 1.52E+08 - - - 4.741 0.9941 221125_WJC_METTL3_EV_vs_WT_F08.05266.05266.2 4.55E-06 13/22 V.GGTSDVEVNEK[136.11]K[136.11].D "sp|P10809|CH60_HUMAN,tr|A0A7I2V2X6|A0A7I2V2X6_HUMAN,tr|A0A7I2YQK6|A0A7I2YQK6_HUMAN,tr|A0A7I2V599|A0A7I2V599_HUMAN" 4 1277.6434 1.37 111310 5266 2 1277.642384 639.829 "60 kDa heat shock protein, mitochondrial OS=Homo sapiens OX=9606 GN=HSPD1 PE=1 SV=2" 4.68 1494.1 - 1.41E+07 - - - -0.803 - 2.613 0.532 - 806.5 1 1 0 -0.001 12 0 0 0 2.08E+08 1.52E+08 - - - 5.4973 0.9999 221125_WJC_METTL3_EV_vs_WT_F08.05267.05267.3 3.89E-05 Dec-36 K.GQADYEEVKK.E "sp|Q13948|CASP_HUMAN,sp|P39880|CUX1_HUMAN,tr|A0A2R8Y852|A0A2R8Y852_HUMAN,tr|A0A2R8YDI1|A0A2R8YDI1_HUMAN" 4 1165.5615 1.39 111311 5267 3 1165.559104 389.5278 Protein CASP OS=Homo sapiens OX=9606 GN=CUX1 PE=1 SV=2 4.68 1494.1 - 6.37E+06 - - - -2.0711 - 2.306 0.432 - 228.7 1 2 0 -0.0024 10 0 0 0 5.50E+07 3.97E+07 - - - 5.7958 0.9326 221125_WJC_METTL3_EV_vs_WT_F08.05270.05270.2 0.0108 20-Oct G.GTSDVEVNEK[136.11]K[136.11].D "sp|P10809|CH60_HUMAN,tr|A0A7I2V2X6|A0A7I2V2X6_HUMAN,tr|A0A7I2YQK6|A0A7I2YQK6_HUMAN,tr|A0A7I2V599|A0A7I2V599_HUMAN" 4 1220.6219 1.08 111314 5270 2 1220.617717 611.3182 "60 kDa heat shock protein, mitochondrial OS=Homo sapiens OX=9606 GN=HSPD1 PE=1 SV=2" 4.68 1494.3 - 4.14E+06 - - - -3.4646 - 2.202 0.402 - 484.2 1 1 0 -0.0042 11 0 0 0 3.84E+07 3.55E+07 - - - 4.1443 0.907 221125_WJC_METTL3_EV_vs_WT_F08.05272.05272.2 8.11E-05 20-Dec G.GTSDVEVNEKK.D "sp|P10809|CH60_HUMAN,tr|A0A7I2V2X6|A0A7I2V2X6_HUMAN,tr|A0A7I2YQK6|A0A7I2YQK6_HUMAN,tr|A0A7I2V599|A0A7I2V599_HUMAN" 4 1204.5935 1.08 111316 5272 2 1204.587583 603.304 "60 kDa heat shock protein, mitochondrial OS=Homo sapiens OX=9606 GN=HSPD1 PE=1 SV=2" 4.68 1494.4 - 3.34E+06 - - - -4.9502 - 2.529 0.524 - 732.5 1 1 0 -0.006 11 0 0 0 3.84E+07 3.55E+07 - - - 5.4194 0.9852 221125_WJC_METTL3_EV_vs_WT_F08.05273.05273.2 0.0194 16-Oct K.QNK[136.11]LEQVEK[136.11].E "sp|P48047|ATPO_HUMAN,tr|H7C086|H7C086_HUMAN,tr|H7C0C1|H7C0C1_HUMAN,tr|A0A494C0K9|A0A494C0K9_HUMAN" 4 1130.6266 1.02 111317 5273 2 1130.623828 566.3206 "ATP synthase subunit O, mitochondrial OS=Homo sapiens OX=9606 GN=ATP5PO PE=1 SV=1" 6.14 1494.6 - 3.10E+06 - - - -2.4853 - 1.942 0.298 - 385.7 1 2 1 -0.0028 9 0 0 0 8.11E+07 7.96E+07 - - - 3.1613 0.9999 221125_WJC_METTL3_EV_vs_WT_F08.05274.05274.2 1.57E-07 18-Nov R.ESGAHC[160.03]PLC[160.03]R[166.11].G "sp|Q8WVD3|RN138_HUMAN,tr|J3QKM8|J3QKM8_HUMAN,tr|J3KSI2|J3KSI2_HUMAN,tr|J3KRU4|J3KRU4_HUMAN" 4 1195.5102 1.6 111318 5274 2 1195.509191 598.7624 E3 ubiquitin-protein ligase RNF138 OS=Homo sapiens OX=9606 GN=RNF138 PE=1 SV=1 6.82 1494.6 - 2.22E+06 - - - -0.8289 - 1.891 0.598 - 432.8 1 2 0 -0.001 10 0 0 0 2.65E+07 1.66E+07 - - - 5.2359 0.9997 221125_WJC_METTL3_EV_vs_WT_F08.05275.05275.2 1.96E-06 16/26 K.SPPSTGSTYGSSQK.E "sp|Q9Y2W1|TR150_HUMAN,tr|A0A3B3ITZ9|A0A3B3ITZ9_HUMAN" 2 1382.6314 2.16 111319 5275 2 1382.634293 692.323 Thyroid hormone receptor-associated protein 3 OS=Homo sapiens OX=9606 GN=THRAP3 PE=1 SV=2 8.31 1494.8 - 2.81E+06 - - - 2.1011 - 2.55 0.481 - 392.7 1 2 0 0.0029 14 0 0 0 5.62E+07 2.61E+07 - - - 4.9418 0.9999 221125_WJC_METTL3_EV_vs_WT_F08.05281.05281.3 0.000128 Dec-40 R.STFETEHAGQR.D "sp|P49750|YLPM1_HUMAN,tr|H0YIQ2|H0YIQ2_HUMAN,tr|F8VU51|F8VU51_HUMAN,tr|H0YI23|H0YI23_HUMAN" 4 1261.5687 1.7 111323 5281 3 1261.566721 421.5302 YLP motif-containing protein 1 OS=Homo sapiens OX=9606 GN=YLPM1 PE=1 SV=4 5.38 1495.4 - 5.95E+06 - - - -1.5909 - 2.256 0.427 - 263.9 1 2 0 -0.002 11 0 0 0 4.40E+07 2.58E+07 - - - 5.6114 0.9999 221125_WJC_METTL3_EV_vs_WT_F08.05282.05282.3 3.28E-05 14/36 K.VSR[166.11]PENEQLR[166.11].N "sp|Q8ND56|LS14A_HUMAN,tr|A0A140TA76|A0A140TA76_HUMAN,tr|K7EMZ9|K7EMZ9_HUMAN" 3 1246.6533 0.99 111324 5282 3 1246.650926 416.5584 Protein LSM14 homolog A OS=Homo sapiens OX=9606 GN=LSM14A PE=1 SV=3 6.11 1495.4 - 7.58E+06 - - - -1.8947 - 2.506 0.466 - 364.7 1 2 0 -0.0024 10 0 0 0 2.07E+09 2.10E+09 - - - 6.4178 0.9847 221125_WJC_METTL3_EV_vs_WT_F08.05284.05284.3 0.714 Oct-48 R.LGNSHQPEKPLVR.L "sp|P49959|MRE11_HUMAN,tr|F8W7U8|F8W7U8_HUMAN" 2 1473.8052 1.37 111326 5284 3 1473.80657 492.2757 Double-strand break repair protein MRE11 OS=Homo sapiens OX=9606 GN=MRE11 PE=1 SV=3 8.75 1495.5 - 7.17E+06 - - - 0.9221 - 1.596 0.16 - 102.8 1 2 0 0.0014 13 0 0 0 2.27E+07 1.66E+07 - - - 1.591 0.9908 221125_WJC_METTL3_EV_vs_WT_F08.05286.05286.2 0.048 14-Aug K.ESPHWQSK.S sp|Q5JSZ5|PRC2B_HUMAN 1 997.4617 1.34 111328 5286 2 997.458119 499.7381 Protein PRRC2B OS=Homo sapiens OX=9606 GN=PRRC2B PE=1 SV=2 6.85 1495.7 - 2.64E+06 - - - -3.6342 - 1.523 0.248 - 238.9 1 2 0 -0.0036 8 0 0 0 2.74E+07 2.05E+07 - - - 2.1403 0.9994 221125_WJC_METTL3_EV_vs_WT_F08.05288.05288.2 0.00061 22-Nov K.NVAQPPASSQGR.Q "sp|Q6ZN17|LN28B_HUMAN,tr|A0A1B0GTK2|A0A1B0GTK2_HUMAN,tr|A0A1B0GVD3|A0A1B0GVD3_HUMAN" 3 1210.6054 0.32 111330 5288 2 1210.605149 606.31 Protein lin-28 homolog B OS=Homo sapiens OX=9606 GN=LIN28B PE=1 SV=1 9.75 1495.9 - 1.49E+06 - - - -0.247 - 2.177 0.24 - 297.8 1 2 0 -0.0003 12 0 0 0 1.16E+07 3.67E+07 - - - 2.8605 1 221125_WJC_METTL3_EV_vs_WT_F08.05291.05291.3 1.21E-05 Dec-36 K.VSRPENEQLR.N "sp|Q8ND56|LS14A_HUMAN,tr|A0A140TA76|A0A140TA76_HUMAN,tr|K7EMZ9|K7EMZ9_HUMAN" 3 1226.6367 0.99 111331 5291 3 1226.635028 409.8862 Protein LSM14 homolog A OS=Homo sapiens OX=9606 GN=LSM14A PE=1 SV=3 6.11 1496.3 - 1.94E+07 - - - -1.4022 - 2.39 0.5 - 234.8 1 2 0 -0.0017 10 0 0 0 2.07E+09 2.10E+09 - - - 6.6586 0.9516 221125_WJC_METTL3_EV_vs_WT_F08.05294.05294.3 0.00188 Nov-40 V.LGQPHHELDSK.T "sp|Q96DH6|MSI2H_HUMAN,tr|B4DHE8|B4DHE8_HUMAN,tr|A0A6Q8PF05|A0A6Q8PF05_HUMAN,tr|J3QKT5|J3QKT5_HUMAN,tr|A0A6Q8PFU8|A0A6Q8PFU8_HUMAN,tr|J3KTC1|J3KTC1_HUMAN,tr|A0A6Q8PHT3|A0A6Q8PHT3_HUMAN" 7 1259.6258 1.37 111334 5294 3 1259.623319 420.8826 RNA-binding protein Musashi homolog 2 OS=Homo sapiens OX=9606 GN=MSI2 PE=1 SV=1 5.99 1496.4 - 7.34E+06 - - - -2.0085 - 2.182 0.32 - 197.6 1 1 0 -0.0025 11 0 0 0 7.11E+07 5.18E+07 - - - 4.3235 1 221125_WJC_METTL3_EV_vs_WT_F08.05295.05295.2 1.24E-05 16/22 K.VLGQPHHELDSK[136.11].T "sp|Q96DH6|MSI2H_HUMAN,tr|B4DHE8|B4DHE8_HUMAN,tr|A0A6Q8PF05|A0A6Q8PF05_HUMAN,tr|J3QKT5|J3QKT5_HUMAN,tr|A0A6Q8PFU8|A0A6Q8PFU8_HUMAN,tr|J3KTC1|J3KTC1_HUMAN,tr|A0A6Q8PHT3|A0A6Q8PHT3_HUMAN" 7 1366.7085 1.26 111335 5295 2 1366.707008 684.3615 RNA-binding protein Musashi homolog 2 OS=Homo sapiens OX=9606 GN=MSI2 PE=1 SV=1 5.99 1496.4 - 5.07E+06 - - - -1.0646 - 3.084 0.572 - 959.6 1 2 0 -0.0015 12 0 0 0 8.86E+07 7.02E+07 - - - 6.2286 1 221125_WJC_METTL3_EV_vs_WT_F08.05297.05297.2 1.83E-05 16/22 K.IHMGSC[160.03]AENTAK.K "sp|P24752|THIL_HUMAN,tr|A0A5F9ZHJ7|A0A5F9ZHJ7_HUMAN,tr|A0A5F9ZHD4|A0A5F9ZHD4_HUMAN,tr|A0A5F9ZHJ0|A0A5F9ZHJ0_HUMAN,tr|A0A5F9ZHL1|A0A5F9ZHL1_HUMAN,tr|A0A5F9ZI66|A0A5F9ZI66_HUMAN" 6 1317.5806 1.23 111337 5297 2 1317.578685 659.7976 "Acetyl-CoA acetyltransferase, mitochondrial OS=Homo sapiens OX=9606 GN=ACAT1 PE=1 SV=1" 6.74 1496.7 - 2.46E+06 - - - -1.42 - 2.822 0.639 - 657.9 1 2 0 -0.0019 12 0 0 0 3.85E+07 3.14E+07 - - - 6.4898 0.9972 221125_WJC_METTL3_EV_vs_WT_F08.05299.05299.3 0.0508 Aug-36 R.EAQQQQHLYR[166.11].V sp|Q92793|CBP_HUMAN 1 1309.6403 0.97 111339 5299 3 1309.640831 437.554 CREB-binding protein OS=Homo sapiens OX=9606 GN=CREBBP PE=1 SV=3 6.85 1496.8 - 1.79E+06 - - - 0.4307 - 1.739 0.22 - 111.2 1 2 0 0.0006 10 0 0 0 1.28E+07 1.33E+07 - - - 2.6085 0.9999 221125_WJC_METTL3_EV_vs_WT_F08.05302.05302.3 0.00026 Nov-44 K.VLGQPHHELDSK[136.11].T "sp|Q96DH6|MSI2H_HUMAN,tr|B4DHE8|B4DHE8_HUMAN,tr|A0A6Q8PF05|A0A6Q8PF05_HUMAN,tr|J3QKT5|J3QKT5_HUMAN,tr|A0A6Q8PFU8|A0A6Q8PFU8_HUMAN,tr|J3KTC1|J3KTC1_HUMAN,tr|A0A6Q8PHT3|A0A6Q8PHT3_HUMAN" 7 1366.7085 1.49 111340 5302 3 1366.70488 456.5768 RNA-binding protein Musashi homolog 2 OS=Homo sapiens OX=9606 GN=MSI2 PE=1 SV=1 5.99 1497.2 - 7.70E+07 - - - -2.6216 - 2.454 0.469 - 196.5 1 2 0 -0.0036 12 0 0 0 1.08E+09 7.24E+08 - - - 6.2562 0.9996 221125_WJC_METTL3_EV_vs_WT_F08.05303.05303.2 0.0216 18-Nov K.VSR[166.11]PENEQLR[166.11].N "sp|Q8ND56|LS14A_HUMAN,tr|A0A140TA76|A0A140TA76_HUMAN,tr|K7EMZ9|K7EMZ9_HUMAN" 3 1246.6533 1.06 111341 5303 2 1246.652073 624.3339 Protein LSM14 homolog A OS=Homo sapiens OX=9606 GN=LSM14A PE=1 SV=3 6.11 1497.2 - 6.36E+06 - - - -0.9746 - 1.804 0.38 - 203.7 1 2 0 -0.0012 10 0 0 0 2.39E+08 2.26E+08 - - - 3.4942 0.9996 221125_WJC_METTL3_EV_vs_WT_F08.05304.05304.2 0.00123 18-Dec K.VSRPENEQLR.N "sp|Q8ND56|LS14A_HUMAN,tr|A0A140TA76|A0A140TA76_HUMAN,tr|K7EMZ9|K7EMZ9_HUMAN" 3 1226.6367 1.06 111342 5304 2 1226.634822 614.3257 Protein LSM14 homolog A OS=Homo sapiens OX=9606 GN=LSM14A PE=1 SV=3 6.11 1497.3 - 5.77E+06 - - - -1.5701 - 1.914 0.389 - 215.4 1 2 0 -0.0019 10 0 0 0 2.39E+08 2.26E+08 - - - 3.7257 0.9994 221125_WJC_METTL3_EV_vs_WT_F08.05306.05306.3 0.00294 Nov-36 K.ENEVQSLHSK[136.11].L sp|Q86UP2|KTN1_HUMAN 1 1177.5819 1.92 111344 5306 3 1177.579633 393.5346 Kinectin OS=Homo sapiens OX=9606 GN=KTN1 PE=1 SV=1 5.4 1497.4 - 4.93E+06 - - - -1.8963 - 1.81 0.346 - 163 1 2 0 -0.0022 10 0 0 0 7.30E+07 3.81E+07 - - - 4.1297 0.9927 221125_WJC_METTL3_EV_vs_WT_F08.05309.05309.3 0.0795 Sep-36 R.YKQSLDDAAK.T sp|P15924|DESP_HUMAN 1 1137.5666 3.98 111347 5309 3 1137.564882 380.1961 Desmoplakin OS=Homo sapiens OX=9606 GN=DSP PE=1 SV=3 5.96 1497.6 - 3.25E+06 - - - -1.5129 - 1.845 0.255 - 118.5 1 2 1 -0.0017 10 0 0 0 1.70E+07 4.26E+06 - - - 3.1712 0.9996 221125_WJC_METTL3_EV_vs_WT_F08.05310.05310.2 0.00211 24-Nov R.RGFSDSGGGPPAK.Q "sp|Q9H307|PININ_HUMAN,tr|G3V5F0|G3V5F0_HUMAN,tr|G3V579|G3V579_HUMAN" 3 1231.5945 2.28 111348 5310 2 1231.592813 616.8046 Pinin OS=Homo sapiens OX=9606 GN=PNN PE=1 SV=5 8.75 1497.7 - 3.18E+06 - - - -1.4096 - 2.205 0.377 - 202.9 1 2 0 -0.0017 13 0 0 0 3.72E+07 1.63E+07 - - - 3.8544 0.9879 221125_WJC_METTL3_EV_vs_WT_F08.05311.05311.2 0.00308 14/20 V.LGQPHHELDSK[136.11].T "sp|Q96DH6|MSI2H_HUMAN,tr|B4DHE8|B4DHE8_HUMAN,tr|A0A6Q8PF05|A0A6Q8PF05_HUMAN,tr|J3QKT5|J3QKT5_HUMAN,tr|A0A6Q8PFU8|A0A6Q8PFU8_HUMAN,tr|J3KTC1|J3KTC1_HUMAN,tr|A0A6Q8PHT3|A0A6Q8PHT3_HUMAN" 7 1267.64 2.14 111349 5311 2 1267.637813 634.8273 RNA-binding protein Musashi homolog 2 OS=Homo sapiens OX=9606 GN=MSI2 PE=1 SV=1 5.99 1497.8 - 2.12E+06 - - - -1.7639 - 2.884 0.42 - 720.8 1 1 0 -0.0022 11 0 0 0 3.33E+07 1.56E+07 - - - 5.0077 0.9958 221125_WJC_METTL3_EV_vs_WT_F08.05314.05314.2 0.00333 18-Sep R.YKQSLDDAAK.T sp|P15924|DESP_HUMAN 1 1137.5666 3.36 111352 5314 2 1137.567419 569.7906 Desmoplakin OS=Homo sapiens OX=9606 GN=DSP PE=1 SV=3 5.96 1498.2 - 1.33E+06 - - - 0.7173 - 1.795 0.384 - 186.4 1 2 1 0.0008 10 0 0 0 1.26E+07 3.74E+06 - - - 3.5099 1 221125_WJC_METTL3_EV_vs_WT_F08.05315.05315.2 3.38E-08 14/26 K.SPPSTGSTYGSSQK[136.11].E "sp|Q9Y2W1|TR150_HUMAN,tr|A0A3B3ITZ9|A0A3B3ITZ9_HUMAN" 2 1390.6456 2.17 111353 5315 2 1390.646937 696.3301 Thyroid hormone receptor-associated protein 3 OS=Homo sapiens OX=9606 GN=THRAP3 PE=1 SV=2 8.31 1498.3 - 1.23E+06 - - - 0.9701 - 2.651 0.632 - 422.8 1 2 0 0.0013 14 0 0 0 5.62E+07 2.59E+07 - - - 6.1551 0.9595 221125_WJC_METTL3_EV_vs_WT_F08.05316.05316.2 0.000376 14-Nov K.KYYLHDDR.E "sp|Q9Y2W1|TR150_HUMAN,tr|A0A3B3ITZ9|A0A3B3ITZ9_HUMAN" 2 1108.5302 2.12 111354 5316 2 1109.530497 555.2724 Thyroid hormone receptor-associated protein 3 OS=Homo sapiens OX=9606 GN=THRAP3 PE=1 SV=2 6.75 1498.4 - 584812 - - - 902.4012 - 1.854 0.414 - 438.5 1 2 0 1.0003 8 0 0 0 2.64E+07 1.25E+07 - - - 3.6466 0.9866 221125_WJC_METTL3_EV_vs_WT_F08.05319.05319.2 0.000892 16-Nov V.SRPENEQLR.N "sp|Q8ND56|LS14A_HUMAN,tr|A0A140TA76|A0A140TA76_HUMAN,tr|K7EMZ9|K7EMZ9_HUMAN" 3 1127.5683 1.25 111355 5319 2 1127.567083 564.7914 Protein LSM14 homolog A OS=Homo sapiens OX=9606 GN=LSM14A PE=1 SV=3 5.86 1498.8 - 1.19E+07 - - - -1.1095 - 1.962 0.438 - 245.1 1 1 0 -0.0013 9 0 0 0 1.58E+08 1.26E+08 - - - 4.2255 1 221125_WJC_METTL3_EV_vs_WT_F08.05320.05320.2 8.71E-08 16/22 K.VLGQPHHELDSK.T "sp|Q96DH6|MSI2H_HUMAN,tr|B4DHE8|B4DHE8_HUMAN,tr|A0A6Q8PF05|A0A6Q8PF05_HUMAN,tr|J3QKT5|J3QKT5_HUMAN,tr|A0A6Q8PFU8|A0A6Q8PFU8_HUMAN,tr|J3KTC1|J3KTC1_HUMAN,tr|A0A6Q8PHT3|A0A6Q8PHT3_HUMAN" 7 1358.6943 1.26 111356 5320 2 1358.692976 680.3544 RNA-binding protein Musashi homolog 2 OS=Homo sapiens OX=9606 GN=MSI2 PE=1 SV=1 5.99 1498.9 - 6.82E+06 - - - -0.9472 - 3.057 0.648 - 978.9 1 2 0 -0.0013 12 0 0 0 8.86E+07 7.02E+07 - - - 6.7669 0.9824 221125_WJC_METTL3_EV_vs_WT_F08.05322.05322.3 0.00182 Dec-40 V.LGQPHHELDSK[136.11].T "sp|Q96DH6|MSI2H_HUMAN,tr|B4DHE8|B4DHE8_HUMAN,tr|A0A6Q8PF05|A0A6Q8PF05_HUMAN,tr|J3QKT5|J3QKT5_HUMAN,tr|A0A6Q8PFU8|A0A6Q8PFU8_HUMAN,tr|J3KTC1|J3KTC1_HUMAN,tr|A0A6Q8PHT3|A0A6Q8PHT3_HUMAN" 7 1267.64 1.61 111358 5322 3 1267.637453 423.554 RNA-binding protein Musashi homolog 2 OS=Homo sapiens OX=9606 GN=MSI2 PE=1 SV=1 5.99 1499 - 4.16E+06 - - - -2.0479 - 2.267 0.396 - 240.7 1 1 0 -0.0026 11 0 0 0 9.41E+07 5.84E+07 - - - 5.2794 0.9994 221125_WJC_METTL3_EV_vs_WT_F08.05323.05323.3 0.142 Oct-36 K.VSRPENEQLR[166.11].N "sp|Q8ND56|LS14A_HUMAN,tr|A0A140TA76|A0A140TA76_HUMAN,tr|K7EMZ9|K7EMZ9_HUMAN" 3 1236.645 - 111359 5323 3 1236.645673 413.2223 Protein LSM14 homolog A OS=Homo sapiens OX=9606 GN=LSM14A PE=1 SV=3 6.11 1499 - 4.03E+06 - - - 0.5297 - 1.97 0.286 - 154 1 2 0 0.0007 10 0 0 0 - - - - - 3.7086 1 221125_WJC_METTL3_EV_vs_WT_F08.05324.05324.3 5.22E-05 13/32 K.C[160.03]EFDGC[160.03]DRK.F sp|Q96T25|ZIC5_HUMAN 1 1185.4543 1.77 111360 5324 3 1185.453416 396.1587 Zinc finger protein ZIC 5 OS=Homo sapiens OX=9606 GN=ZIC5 PE=1 SV=2 4.56 1499.1 - 2.78E+06 - - - -0.7398 - 2.183 0.463 - 322 1 2 0 -0.0009 9 0 0 0 1.51E+07 8.52E+06 - - - 6.0546 0.9932 221125_WJC_METTL3_EV_vs_WT_F08.05325.05325.2 0.005 17/20 V.LGQPHHELDSK.T "sp|Q96DH6|MSI2H_HUMAN,tr|B4DHE8|B4DHE8_HUMAN,tr|A0A6Q8PF05|A0A6Q8PF05_HUMAN,tr|J3QKT5|J3QKT5_HUMAN,tr|A0A6Q8PFU8|A0A6Q8PFU8_HUMAN,tr|J3KTC1|J3KTC1_HUMAN,tr|A0A6Q8PHT3|A0A6Q8PHT3_HUMAN" 7 1259.6258 2.06 111361 5325 2 1259.626463 630.8202 RNA-binding protein Musashi homolog 2 OS=Homo sapiens OX=9606 GN=MSI2 PE=1 SV=1 5.99 1499.2 - 2.69E+06 - - - 0.4874 - 3.086 0.411 - 1118.5 1 1 0 0.0006 11 0 0 0 3.20E+07 1.56E+07 - - - 5.1249 0.9922 221125_WJC_METTL3_EV_vs_WT_F08.05327.05327.2 0.478 18-Nov K.ENEVQSLHSK[136.11].L sp|Q86UP2|KTN1_HUMAN 1 1177.5819 2.25 111363 5327 2 1177.577678 589.7982 Kinectin OS=Homo sapiens OX=9606 GN=KTN1 PE=1 SV=1 5.4 1499.3 - 1.89E+06 - - - -3.5564 - 1.777 0.216 - 506.4 1 2 0 -0.0042 10 0 0 0 5.81E+07 2.58E+07 - - - 2.2399 0.9966 221125_WJC_METTL3_EV_vs_WT_F08.05335.05335.2 3.94E-05 18-Oct R.NKFNQVESDK.L sp|Q10471|GALT2_HUMAN 1 1207.5833 3.53 111371 5335 2 1207.580803 604.7989 Polypeptide N-acetylgalactosaminyltransferase 2 OS=Homo sapiens OX=9606 GN=GALNT2 PE=1 SV=1 6.07 1500.4 - 603802 - - - -2.081 - 2.075 0.486 - 329.8 1 2 1 -0.0025 10 0 0 0 1.14E+07 3.24E+06 - - - 4.6674 0.9112 221125_WJC_METTL3_EV_vs_WT_F08.05341.05341.3 0.153 Jul-48 R.MAQPAWGLSASHR.A tr|Q5T4F6|Q5T4F6_HUMAN 1 1410.6827 20.11 111375 5341 3 1410.687203 471.2348 Cartilage acidic protein 1 (Fragment) OS=Homo sapiens OX=9606 GN=CRTAC1 PE=1 SV=1 9.52 1500.9 - 6.68E+06 - - - 3.2254 - 1.362 0.178 - 47.2 1 2 0 0.0046 13 0 0 0 8.41E+07 4.18E+06 - - - 1.3609 0.9856 221125_WJC_METTL3_EV_vs_WT_F08.05342.05342.2 5.30E-05 18-Aug G.EVAGTVTGQK[136.11].R "sp|Q86U44|MTA70_HUMAN,tr|F5H6D8|F5H6D8_HUMAN,tr|H0YFV6|H0YFV6_HUMAN,tr|B4DTN4|B4DTN4_HUMAN" 4 996.5331 0.03 111376 5342 2 996.532182 499.2738 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 6.1 1500.9 - 3.70E+06 - - - -0.9463 - 1.678 0.48 - 223.6 1 1 0 -0.0009 10 0 0 0 1.19E+06 3.50E+07 - - - 4.0308 0.8392 221125_WJC_METTL3_EV_vs_WT_F08.05343.05343.3 0.529 Jun-48 R.GPPSPRPAGPTPR.G sp|Q14681|KCTD2_HUMAN 1 1285.6891 5.48 111377 5343 3 1285.687669 429.5703 BTB\POZ domain-containing protein KCTD2 OS=Homo sapiens OX=9606 GN=KCTD2 PE=1 SV=3 12 1501 - 8.88E+06 - - - -1.127 - 1.106 0.123 - 40.4 1 2 0 -0.0014 13 0 0 0 4.93E+08 9.00E+07 - - - 0.1841 0.9996 221125_WJC_METTL3_EV_vs_WT_F08.05354.05354.2 0.00646 14-Oct K.TDSEKPFR.G "sp|Q9Y2W1|TR150_HUMAN,tr|A0A3B3ITZ9|A0A3B3ITZ9_HUMAN" 2 978.4771 2.67 111386 5354 2 978.475609 490.2458 Thyroid hormone receptor-associated protein 3 OS=Homo sapiens OX=9606 GN=THRAP3 PE=1 SV=2 5.74 1502.2 - 6.62E+06 - - - -1.4829 - 1.985 0.374 - 444.5 1 2 0 -0.0015 8 0 0 0 7.76E+07 2.91E+07 - - - 3.8707 0.9999 221125_WJC_METTL3_EV_vs_WT_F08.05355.05355.2 0.000197 20-Nov R.GGEDTNDLQQK.L "sp|O95785|WIZ_HUMAN,tr|A0A669KBG4|A0A669KBG4_HUMAN,tr|A0A2R8YFV2|A0A2R8YFV2_HUMAN,tr|A0A669KAV7|A0A669KAV7_HUMAN,tr|M0QXA7|M0QXA7_HUMAN,tr|A0A669KBH9|A0A669KBH9_HUMAN,tr|B9EGQ5|B9EGQ5_HUMAN" 7 1203.5368 1.57 111387 5355 2 1203.53605 602.7757 Protein Wiz OS=Homo sapiens OX=9606 GN=WIZ PE=1 SV=2 4.03 1502.3 - 3.48E+06 - - - -0.5899 - 2.338 0.56 - 535.9 1 2 0 -0.0007 11 0 0 0 5.87E+07 3.74E+07 - - - 5.4745 0.9999 221125_WJC_METTL3_EV_vs_WT_F08.05356.05356.2 1.45E-06 20-Dec R.GGEDTNDLQQK[136.11].L "sp|O95785|WIZ_HUMAN,tr|A0A669KBG4|A0A669KBG4_HUMAN,tr|A0A2R8YFV2|A0A2R8YFV2_HUMAN,tr|A0A669KAV7|A0A669KAV7_HUMAN,tr|M0QXA7|M0QXA7_HUMAN,tr|A0A669KBH9|A0A669KBH9_HUMAN,tr|B9EGQ5|B9EGQ5_HUMAN" 7 1211.551 1.59 111388 5356 2 1211.550698 606.7828 Protein Wiz OS=Homo sapiens OX=9606 GN=WIZ PE=1 SV=2 4.03 1502.4 - 2.53E+06 - - - -0.2163 - 2.402 0.52 - 665.2 1 2 0 -0.0003 11 0 0 0 5.87E+07 3.69E+07 - - - 5.2522 0.9999 221125_WJC_METTL3_EV_vs_WT_F08.05362.05362.2 6.09E-06 24-Dec K.AQPAQPADEPAEK.A "sp|P25786|PSA1_HUMAN,tr|F5GX11|F5GX11_HUMAN" 2 1350.6416 999 111394 5362 2 1350.641738 676.3281 Proteasome subunit alpha type-1 OS=Homo sapiens OX=9606 GN=PSMA1 PE=1 SV=1 4.14 1503.1 - 398802 - - - 0.1325 - 1.893 0.598 - 392.5 1 2 0 0.0002 13 0 0 0 3.00E+06 0.00E+00 - - - 5.0956 0.9999 221125_WJC_METTL3_EV_vs_WT_F08.05365.05365.3 0.000177 13/32 R.RFEKPLEEK.G sp|Q8NC51|PAIRB_HUMAN 1 1174.6346 0.8 111395 5365 3 1174.63404 392.5522 Plasminogen activator inhibitor 1 RNA-binding protein OS=Homo sapiens OX=9606 GN=SERBP1 PE=1 SV=2 6.23 1503.6 - 1.10E+07 - - - -0.4963 - 2.617 0.355 - 294.9 1 2 0 -0.0006 9 0 0 0 7.49E+08 9.38E+08 - - - 5.3971 0.9999 221125_WJC_METTL3_EV_vs_WT_F08.05366.05366.2 0.00965 15/20 R.K[136.11]PNEGADGQWK[136.11].K sp|Q8NC51|PAIRB_HUMAN 1 1244.612 0.89 111396 5366 2 1244.611278 623.3133 Plasminogen activator inhibitor 1 RNA-binding protein OS=Homo sapiens OX=9606 GN=SERBP1 PE=1 SV=2 6.07 1503.6 - 8.82E+06 - - - -0.6203 - 2.837 0.516 - 595.7 1 2 0 -0.0008 11 0 0 0 7.15E+07 8.04E+07 - - - 5.6728 0.934 221125_WJC_METTL3_EV_vs_WT_F08.05369.05369.3 0.608 Jul-48 R.GPPSPR[166.11]PAGPTPR[166.11].G sp|Q14681|KCTD2_HUMAN 1 1305.7057 5.48 111398 5369 3 1305.705376 436.2425 BTB\POZ domain-containing protein KCTD2 OS=Homo sapiens OX=9606 GN=KCTD2 PE=1 SV=3 12 1503.7 - 3.02E+06 - - - -0.216 - 1.393 0.125 - 50.1 2 2 0 -0.0003 13 0 0 0 4.93E+08 9.00E+07 - - - 0.6929 0.8129 221125_WJC_METTL3_EV_vs_WT_F08.05370.05370.3 0.00174 Oct-52 A.AAANGLGAEKDPGR.S sp|Q9H7S9|ZN703_HUMAN 1 1325.6688 2.62 111399 5370 3 1325.667279 442.8969 Zinc finger protein 703 OS=Homo sapiens OX=9606 GN=ZNF703 PE=1 SV=1 6.11 1503.8 - 2.02E+06 - - - -1.13 - 2.052 0.33 - 88.8 3 1 1 -0.0015 14 0 0 0 1.82E+07 6.96E+06 - - - 3.9082 0.9854 221125_WJC_METTL3_EV_vs_WT_F08.05372.05372.2 0.04 16-Nov K.TKQEVEISR.R "sp|Q14694|UBP10_HUMAN,tr|H3BQP1|H3BQP1_HUMAN" 2 1088.5826 1.23 111401 5372 2 1088.585715 545.2986 Ubiquitin carboxyl-terminal hydrolase 10 OS=Homo sapiens OX=9606 GN=USP10 PE=1 SV=2 5.81 1504 - 1.04E+06 - - - 2.8725 - 1.951 0.345 - 384.9 1 2 1 0.0031 9 0 0 0 4.49E+07 3.66E+07 - - - 3.5217 0.9997 221125_WJC_METTL3_EV_vs_WT_F08.05375.05375.2 0.000119 24-Oct R.GPPSPRPAGPTPR.G sp|Q14681|KCTD2_HUMAN 1 1285.6891 9.26 111404 5375 2 1285.686825 643.8518 BTB\POZ domain-containing protein KCTD2 OS=Homo sapiens OX=9606 GN=KCTD2 PE=1 SV=3 12 1504.3 - 757137 - - - -1.7835 - 1.897 0.485 - 70.2 1 2 0 -0.0023 13 0 0 0 2.58E+07 2.78E+06 - - - 4.2658 1 221125_WJC_METTL3_EV_vs_WT_F08.05376.05376.2 6.71E-09 26-Nov K.GC[160.03]TPSGEGADSEPR.A sp|Q92917|GPKOW_HUMAN 1 1418.5732 3.53 111405 5376 2 1418.569669 710.2939 G-patch domain and KOW motifs-containing protein OS=Homo sapiens OX=9606 GN=GPKOW PE=1 SV=2 4.14 1504.4 - 718878 - - - -2.5046 - 2.074 0.732 - 357.8 1 2 0 -0.0036 14 0 0 0 6.13E+06 1.73E+06 - - - 6.277 0.9832 221125_WJC_METTL3_EV_vs_WT_F08.05379.05379.2 0.257 16-Aug R.VQIGDHSLR.L sp|Q9Y4B5|MTCL1_HUMAN 1 1023.5461 7.95 111408 5379 2 1023.548304 512.7803 Microtubule cross-linking factor 1 OS=Homo sapiens OX=9606 GN=MTCL1 PE=1 SV=5 6.71 1504.8 - 647983 - - - 2.1123 - 1.428 0.11 - 241.2 1 2 0 0.0022 9 0 0 0 3.11E+06 3.91E+05 - - - 0.8835 0.9978 221125_WJC_METTL3_EV_vs_WT_F08.05380.05380.2 0.00299 13/20 K.DLEDTEANKEK.N sp|Q9UQE7|SMC3_HUMAN 1 1290.5939 1.11 111409 5380 2 1290.59165 646.3042 Structural maintenance of chromosomes protein 3 OS=Homo sapiens OX=9606 GN=SMC3 PE=1 SV=2 4.18 1504.9 - 458482 - - - -1.7744 - 2.369 0.505 - 425.9 1 2 1 -0.0023 11 0 0 0 8.92E+06 8.06E+06 - - - 5.1034 0.8942 221125_WJC_METTL3_EV_vs_WT_F08.05381.05381.2 0.000132 20-Dec K.DLEDTEANK[136.11]EK[136.11].N sp|Q9UQE7|SMC3_HUMAN 1 1306.6223 1.11 111410 5381 2 1307.623083 654.3184 Structural maintenance of chromosomes protein 3 OS=Homo sapiens OX=9606 GN=SMC3 PE=1 SV=2 4.18 1505.1 - 274904 - - - 765.9007 - 2.314 0.526 - 319.1 1 2 1 1.0007 11 0 0 0 8.92E+06 8.06E+06 - - - 4.8814 1 221125_WJC_METTL3_EV_vs_WT_F08.05385.05385.3 6.09E-06 15/40 K.QRPQATAEQIR.L "sp|Q14157|UBP2L_HUMAN,tr|Q5VU78|Q5VU78_HUMAN,tr|F8W726|F8W726_HUMAN,tr|Q5VU81|Q5VU81_HUMAN,tr|Q5VU79|Q5VU79_HUMAN,tr|Q5VU80|Q5VU80_HUMAN,tr|Q5VU77|Q5VU77_HUMAN" 7 1296.6898 2.3 111412 5385 3 1296.689064 433.2372 Ubiquitin-associated protein 2-like OS=Homo sapiens OX=9606 GN=UBAP2L PE=1 SV=2 9.6 1505.6 - 1.13E+08 - - - -0.6038 - 3.006 0.467 - 568.4 1 2 0 -0.0008 11 0 0 0 4.98E+09 2.17E+09 - - - 6.873 1 221125_WJC_METTL3_EV_vs_WT_F08.05386.05386.3 1.97E-05 19/40 K.QR[166.11]PQATAEQIR[166.11].L "sp|Q14157|UBP2L_HUMAN,tr|Q5VU78|Q5VU78_HUMAN,tr|F8W726|F8W726_HUMAN,tr|Q5VU81|Q5VU81_HUMAN,tr|Q5VU79|Q5VU79_HUMAN,tr|Q5VU80|Q5VU80_HUMAN,tr|Q5VU77|Q5VU77_HUMAN" 7 1316.7064 2.3 111413 5386 3 1316.705287 439.9094 Ubiquitin-associated protein 2-like OS=Homo sapiens OX=9606 GN=UBAP2L PE=1 SV=2 9.6 1505.6 - 6.21E+07 - - - -0.8354 - 3.314 0.439 - 957.3 1 2 0 -0.0011 11 0 0 0 4.98E+09 2.17E+09 - - - 6.8379 0.9998 221125_WJC_METTL3_EV_vs_WT_F08.05387.05387.2 0.00806 13/16 R.RSEPIYNSR.C sp|Q5T749|KPRP_HUMAN 1 1120.5625 999 111414 5387 2 1120.561837 561.2885 Keratinocyte proline-rich protein OS=Homo sapiens OX=9606 GN=KPRP PE=1 SV=1 8.75 1505.7 - 4.01E+07 - - - -0.6104 - 2.473 0.37 - 341.9 1 2 0 -0.0007 9 0 0 0 3.23E+08 0.00E+00 - - - 4.3931 1 221125_WJC_METTL3_EV_vs_WT_F08.05388.05388.3 7.10E-06 Dec-40 R.K[136.11]PNEGADGQWK[136.11].K sp|Q8NC51|PAIRB_HUMAN 1 1244.612 1.1 111415 5388 3 1244.61099 415.878 Plasminogen activator inhibitor 1 RNA-binding protein OS=Homo sapiens OX=9606 GN=SERBP1 PE=1 SV=2 6.07 1505.7 - 1.51E+07 - - - -0.8517 - 2.482 0.496 - 380.1 1 2 0 -0.0011 11 0 0 0 2.32E+08 2.11E+08 - - - 6.6521 1 221125_WJC_METTL3_EV_vs_WT_F08.05389.05389.2 0.000352 13/14 N.KYEDEINK.R "sp|P48668|K2C6C_HUMAN,sp|P05787|K2C8_HUMAN,sp|Q01546|K22O_HUMAN,sp|Q7Z794|K2C1B_HUMAN,sp|P12035|K2C3_HUMAN,sp|P04264|K2C1_HUMAN,sp|P04259|K2C6B_HUMAN,sp|P13647|K2C5_HUMAN,sp|P35908|K22E_HUMAN,sp|Q5XKE5|K2C79_HUMAN,sp|P02538|K2C6A_HUMAN,tr|F8VUG2|F8VUG2_HUMAN,tr|F8W0C6|F8W0C6_HUMAN,tr|F8VP67|F8VP67_HUMAN,tr|F8W1U3|F8W1U3_HUMAN" 15 1037.5029 423.73 111416 5389 2 1037.502657 519.7587 "Keratin, type II cytoskeletal 6C OS=Homo sapiens OX=9606 GN=KRT6C PE=1 SV=3" 4.68 1505.7 - 1.33E+07 - - - -0.2728 - 2.581 0.546 - 619.5 1 1 0 -0.0003 8 0 0 0 1.14E+08 2.69E+05 - - - 5.9333 1 221125_WJC_METTL3_EV_vs_WT_F08.05390.05390.3 4.47E-05 Nov-40 R.KPNEGADGQWK.K sp|Q8NC51|PAIRB_HUMAN 1 1228.5837 1.13 111417 5390 3 1228.583933 410.5352 Plasminogen activator inhibitor 1 RNA-binding protein OS=Homo sapiens OX=9606 GN=SERBP1 PE=1 SV=2 6.07 1505.8 - 1.17E+07 - - - 0.2303 - 2.311 0.476 - 337.4 1 2 0 0.0003 11 0 0 0 2.40E+08 2.12E+08 - - - 6.2266 0.9998 221125_WJC_METTL3_EV_vs_WT_F08.05392.05392.2 0.00472 14/20 K.QR[166.11]PQATAEQIR[166.11].L "sp|Q14157|UBP2L_HUMAN,tr|Q5VU78|Q5VU78_HUMAN,tr|F8W726|F8W726_HUMAN,tr|Q5VU81|Q5VU81_HUMAN,tr|Q5VU79|Q5VU79_HUMAN,tr|Q5VU80|Q5VU80_HUMAN,tr|Q5VU77|Q5VU77_HUMAN" 7 1316.7064 2.23 111419 5392 2 1316.70555 659.3605 Ubiquitin-associated protein 2-like OS=Homo sapiens OX=9606 GN=UBAP2L PE=1 SV=2 9.6 1505.8 - 8.29E+06 - - - -0.6357 - 2.413 0.407 - 266.5 1 2 0 -0.0008 11 0 0 0 7.23E+08 3.25E+08 - - - 4.4298 0.9739 221125_WJC_METTL3_EV_vs_WT_F08.05393.05393.3 0.221 Sep-40 K.DLEDTEANK[136.11]EK[136.11].N sp|Q9UQE7|SMC3_HUMAN 1 1306.6223 0.78 111420 5393 3 1306.621546 436.5481 Structural maintenance of chromosomes protein 3 OS=Homo sapiens OX=9606 GN=SMC3 PE=1 SV=2 4.18 1505.9 - 7.47E+06 - - - -0.6077 - 1.301 0.256 - 72.7 1 2 1 -0.0008 11 0 0 0 4.84E+07 6.21E+07 - - - 2.1414 1 221125_WJC_METTL3_EV_vs_WT_F08.05394.05394.3 0.00011 Nov-36 R.RQVDQLTNDK.A "sp|P08670|VIME_HUMAN,tr|B0YJC4|B0YJC4_HUMAN" 2 1215.6208 1.8 111421 5394 3 1215.619342 406.2142 Vimentin OS=Homo sapiens OX=9606 GN=VIM PE=1 SV=4 5.96 1505.9 - 6.14E+06 - - - -1.1698 - 2.368 0.458 - 328.1 1 2 0 -0.0014 10 0 0 0 3.92E+08 2.17E+08 - - - 6.1634 0.9995 221125_WJC_METTL3_EV_vs_WT_F08.05395.05395.3 0.00406 Dec-40 R.LSSVVTQHDSK[136.11].K "sp|P54577|SYYC_HUMAN,tr|A0A6Q8PFX4|A0A6Q8PFX4_HUMAN,tr|A0A6Q8PF15|A0A6Q8PF15_HUMAN,tr|A0A0C4DGZ5|A0A0C4DGZ5_HUMAN,tr|A0A6Q8PFX2|A0A6Q8PFX2_HUMAN" 5 1207.6288 0.9 111422 5395 3 1207.626843 403.5502 "Tyrosine--tRNA ligase, cytoplasmic OS=Homo sapiens OX=9606 GN=YARS1 PE=1 SV=4" 6.74 1506 - 5.79E+06 - - - -1.6338 - 2.16 0.296 - 174.3 1 2 0 -0.002 11 0 0 0 4.98E+07 5.56E+07 - - - 4.0273 0.9996 221125_WJC_METTL3_EV_vs_WT_F08.05397.05397.2 0.0092 16-Dec R.RFEKPLEEK.G sp|Q8NC51|PAIRB_HUMAN 1 1174.6346 0.91 111424 5397 2 1174.633632 588.3246 Plasminogen activator inhibitor 1 RNA-binding protein OS=Homo sapiens OX=9606 GN=SERBP1 PE=1 SV=2 6.23 1506.1 - 4.47E+06 - - - -0.8437 - 2.247 0.291 - 426.6 1 2 0 -0.001 9 0 0 0 7.04E+07 7.78E+07 - - - 3.5322 0.9998 221125_WJC_METTL3_EV_vs_WT_F08.05398.05398.2 0.000487 13/18 R.R[166.11]QVDQLTNDK[136.11].A "sp|P08670|VIME_HUMAN,tr|B0YJC4|B0YJC4_HUMAN" 2 1233.6432 1.92 111425 5398 2 1233.643248 617.8289 Vimentin OS=Homo sapiens OX=9606 GN=VIM PE=1 SV=4 5.96 1506.1 - 3.30E+06 - - - 0.0113 - 2.522 0.321 - 651.3 1 2 0 0 10 0 0 0 3.75E+08 1.95E+08 - - - 3.994 0.9999 221125_WJC_METTL3_EV_vs_WT_F08.05401.05401.3 5.75E-06 15/48 R.LQAENDASKEEVK.E sp|P33176|KINH_HUMAN 1 1459.7155 0.74 111428 5401 3 1459.713434 487.5791 Kinesin-1 heavy chain OS=Homo sapiens OX=9606 GN=KIF5B PE=1 SV=1 4.41 1506.4 - 1.62E+06 - - - -1.3825 - 2.997 0.474 - 391.2 1 2 1 -0.002 13 0 0 0 1.51E+07 2.04E+07 - - - 6.8 0.9971 221125_WJC_METTL3_EV_vs_WT_F08.05406.05406.3 0.000311 Nov-36 R.R[166.11]QVDQLTNDK[136.11].A "sp|P08670|VIME_HUMAN,tr|B0YJC4|B0YJC4_HUMAN" 2 1233.6432 1.8 111431 5406 3 1233.641272 412.2217 Vimentin OS=Homo sapiens OX=9606 GN=VIM PE=1 SV=4 5.96 1507 - 1.67E+07 - - - -1.5904 - 2.238 0.17 - 356 1 2 0 -0.002 10 0 0 0 3.92E+08 2.17E+08 - - - 2.7874 0.9998 221125_WJC_METTL3_EV_vs_WT_F08.05407.05407.2 0.0148 16-Oct R.RYDDPEVQK.D "sp|P38646|GRP75_HUMAN,tr|H0Y8K0|H0Y8K0_HUMAN,tr|A0A7I2V2S7|A0A7I2V2S7_HUMAN,tr|A0A7I2V2G2|A0A7I2V2G2_HUMAN,tr|A0A3B3ITI4|A0A3B3ITI4_HUMAN,tr|A0A7I2V3F7|A0A7I2V3F7_HUMAN,tr|A0A7I2YQB2|A0A7I2YQB2_HUMAN,tr|D6RCD7|D6RCD7_HUMAN" 8 1148.5462 0.54 111432 5407 2 1148.544772 575.2804 "Stress-70 protein, mitochondrial OS=Homo sapiens OX=9606 GN=HSPA9 PE=1 SV=2" 4.56 1507.1 - 8.93E+06 - - - -1.2451 - 2.197 0.419 - 381.4 1 2 0 -0.0014 9 0 0 0 2.76E+08 5.07E+08 - - - 4.4124 0.9998 221125_WJC_METTL3_EV_vs_WT_F08.05412.05412.2 0.00201 14-Oct R.K[136.11]DDEDSFR[166.11].R sp|Q9H0D6|XRN2_HUMAN 1 1028.453 1.21 111437 5412 2 1028.452371 515.2338 5'-3' exoribonuclease 2 OS=Homo sapiens OX=9606 GN=XRN2 PE=1 SV=1 4.23 1507.4 - 2.41E+06 - - - -0.5863 - 2.095 0.417 - 347.9 1 2 0 -0.0006 8 0 0 0 2.10E+07 1.74E+07 - - - 4.3512 0.9998 221125_WJC_METTL3_EV_vs_WT_F08.05413.05413.2 5.77E-05 14-Oct R.KDDEDSFR.R sp|Q9H0D6|XRN2_HUMAN 1 1010.4305 0.53 111438 5413 2 1010.428499 506.2225 5'-3' exoribonuclease 2 OS=Homo sapiens OX=9606 GN=XRN2 PE=1 SV=1 4.23 1507.5 - 2.07E+06 - - - -1.9843 - 1.967 0.527 - 338 1 2 0 -0.002 8 0 0 0 2.49E+07 4.73E+07 - - - 4.9731 0.9999 221125_WJC_METTL3_EV_vs_WT_F08.05417.05417.3 8.77E-05 Nov-32 R.R[166.11]FEK[136.11]PLEEK[136.11].G sp|Q8NC51|PAIRB_HUMAN 1 1200.6713 0.8 111441 5417 3 1200.669407 401.231 Plasminogen activator inhibitor 1 RNA-binding protein OS=Homo sapiens OX=9606 GN=SERBP1 PE=1 SV=2 6.23 1507.9 - 7.56E+07 - - - -1.5708 - 2.205 0.396 - 228.2 1 2 0 -0.0019 9 0 0 0 7.49E+08 9.38E+08 - - - 5.3376 0.9998 221125_WJC_METTL3_EV_vs_WT_F08.05420.05420.2 0.000753 14-Sep K.TDSEK[136.11]PFR[166.11].G "sp|Q9Y2W1|TR150_HUMAN,tr|A0A3B3ITZ9|A0A3B3ITZ9_HUMAN" 2 996.4995 2.56 111443 5420 2 996.499406 499.257 Thyroid hormone receptor-associated protein 3 OS=Homo sapiens OX=9606 GN=THRAP3 PE=1 SV=2 5.74 1508.2 - 2.79E+06 - - - -0.1244 - 1.841 0.438 - 229.3 1 2 0 -0.0001 8 0 0 0 2.19E+08 8.55E+07 - - - 4.1167 0.9983 221125_WJC_METTL3_EV_vs_WT_F08.05429.05429.2 0.00554 16-Sep R.TSQMQELHK.S sp|O43172|PRP4_HUMAN 1 1100.5284 2.58 111449 5429 2 1100.527336 551.2715 U4\U6 small nuclear ribonucleoprotein Prp4 OS=Homo sapiens OX=9606 GN=PRPF4 PE=1 SV=2 6.41 1509.2 - 1.20E+06 - - - -1.0059 - 1.651 0.216 - 241.9 1 2 0 -0.0011 9 0 0 0 1.65E+07 6.41E+06 - - - 2.0866 0.9994 221125_WJC_METTL3_EV_vs_WT_F08.05431.05431.2 0.0471 16-Dec R.R[166.11]FEK[136.11]PLEEK[136.11].G sp|Q8NC51|PAIRB_HUMAN 1 1200.6713 0.91 111450 5431 2 1200.670777 601.3429 Plasminogen activator inhibitor 1 RNA-binding protein OS=Homo sapiens OX=9606 GN=SERBP1 PE=1 SV=2 6.23 1509.4 - 3.50E+06 - - - -0.4298 - 2.038 0.235 - 463.3 1 2 0 -0.0005 9 0 0 0 7.04E+07 7.78E+07 - - - 2.8363 0.9968 221125_WJC_METTL3_EV_vs_WT_F08.05434.05434.2 0.000495 24-Oct K.AEGPGRGDEPSPS.- "sp|Q9NVI7|ATD3A_HUMAN,tr|Q5SV16|Q5SV16_HUMAN" 2 1254.5477 1.74 111452 5434 2 1254.546201 628.2811 ATPase family AAA domain-containing protein 3A OS=Homo sapiens OX=9606 GN=ATAD3A PE=1 SV=2 4.14 1509.8 - 1.22E+06 - - - -1.1622 - 1.964 0.43 - 162.5 1 2 1 -0.0015 13 0 0 0 1.74E+07 1.00E+07 - - - 3.9489 0.7766 221125_WJC_METTL3_EV_vs_WT_F08.05443.05443.3 0.176 Sep-32 K.KDKVVIC[160.03]QR[166.11].V "sp|P49798|RGS4_HUMAN,tr|E9PS05|E9PS05_HUMAN,tr|E9PR32|E9PR32_HUMAN" 3 1154.6469 - 111459 5443 3 1155.649437 385.8896 Regulator of G-protein signaling 4 OS=Homo sapiens OX=9606 GN=RGS4 PE=1 SV=1 9.31 1510.9 - 2.01E+06 - - - 868.2342 - 1.727 0.252 - 150.5 1 2 1 1.0025 9 0 0 0 - - - - - 2.7186 0.966 221125_WJC_METTL3_EV_vs_WT_F08.05444.05444.2 0.0207 24-Jul K.AEGPGR[166.11]GDEPSPS.- "sp|Q9NVI7|ATD3A_HUMAN,tr|Q5SV16|Q5SV16_HUMAN" 2 1264.5559 1.74 111460 5444 2 1264.552685 633.2852 ATPase family AAA domain-containing protein 3A OS=Homo sapiens OX=9606 GN=ATAD3A PE=1 SV=2 4.14 1511 - 606137 - - - -2.5653 - 1.463 0.323 - 90.3 1 2 1 -0.0032 13 0 0 0 1.74E+07 1.00E+07 - - - 2.4022 1 221125_WJC_METTL3_EV_vs_WT_F08.05448.05448.3 9.25E-07 16/40 R.QQPGPSEHIER.R "sp|P50552|VASP_HUMAN,tr|K7EQD0|K7EQD0_HUMAN" 2 1276.616 4.11 111462 5448 3 1276.61475 426.5459 Vasodilator-stimulated phosphoprotein OS=Homo sapiens OX=9606 GN=VASP PE=1 SV=3 5.4 1511.5 - 3.10E+06 - - - -0.9893 - 3.104 0.488 - 777.1 1 2 0 -0.0013 11 0 0 0 4.26E+07 1.04E+07 - - - 7.1982 0.9663 221125_WJC_METTL3_EV_vs_WT_F08.05450.05450.2 0.293 20-Jul S.NDSTDGEPEEK[136.11].R "sp|O14981|BTAF1_HUMAN,tr|A0A0A0MTH9|A0A0A0MTH9_HUMAN" 2 1227.4983 0.92 111464 5450 2 1227.499103 614.7564 TATA-binding protein-associated factor 172 OS=Homo sapiens OX=9606 GN=BTAF1 PE=1 SV=2 3.83 1511.6 - 2.97E+06 - - - 0.6908 - 1.362 0.426 - 168.9 1 1 0 0.0008 11 0 0 0 4.56E+07 4.96E+07 - - - 3.023 0.9995 221125_WJC_METTL3_EV_vs_WT_F08.05452.05452.2 0.00659 18-Sep R.EIQVQHPAAK[136.11].S "sp|P49368|TCPG_HUMAN,tr|E9PRC8|E9PRC8_HUMAN,tr|B4DUR8|B4DUR8_HUMAN,tr|Q5SZX9|Q5SZX9_HUMAN,tr|Q5SZX6|Q5SZX6_HUMAN" 5 1127.6179 0.57 111466 5452 2 1127.617662 564.8162 T-complex protein 1 subunit gamma OS=Homo sapiens OX=9606 GN=CCT3 PE=1 SV=4 6.85 1511.8 - 814864 - - - -0.1729 - 1.55 0.383 - 289.8 1 2 0 -0.0002 10 0 0 0 1.03E+07 1.81E+07 - - - 3.0931 0.9627 221125_WJC_METTL3_EV_vs_WT_F08.05458.05458.2 0.0656 20-May S.NDSTDGEPEEK.R "sp|O14981|BTAF1_HUMAN,tr|A0A0A0MTH9|A0A0A0MTH9_HUMAN" 2 1219.4841 0.93 111470 5458 2 1219.485102 610.7493 TATA-binding protein-associated factor 172 OS=Homo sapiens OX=9606 GN=BTAF1 PE=1 SV=2 3.83 1512.6 - 4.33E+06 - - - 0.8586 - 1.221 0.461 - 87.1 1 1 0 0.001 11 0 0 0 4.61E+07 4.98E+07 - - - 2.9858 0.9993 221125_WJC_METTL3_EV_vs_WT_F08.05460.05460.3 0.0211 Oct-40 R.GKPSEQLTPTR.A "sp|Q14687|GSE1_HUMAN,tr|H0Y613|H0Y613_HUMAN" 2 1212.6463 1.94 111472 5460 3 1212.645945 405.2227 Genetic suppressor element 1 OS=Homo sapiens OX=9606 GN=GSE1 PE=1 SV=3 8.75 1512.7 - 3.52E+06 - - - -0.2515 - 2.061 0.265 - 153.2 1 2 0 -0.0003 11 0 0 0 4.22E+07 2.18E+07 - - - 3.5489 1 221125_WJC_METTL3_EV_vs_WT_F08.05461.05461.3 2.52E-06 13/36 R.K[136.11]QDSGHLDLR[166.11].N "sp|Q86U44|MTA70_HUMAN,tr|B4E349|B4E349_HUMAN,tr|F5H6D8|F5H6D8_HUMAN,tr|B4DTN4|B4DTN4_HUMAN" 4 1185.6221 0.12 111473 5461 3 1185.622711 396.2146 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 6.75 1512.7 - 2.93E+06 - - - 0.5111 - 2.333 0.472 - 217.2 1 2 0 0.0006 10 0 0 0 7.49E+06 6.16E+07 - - - 6.2762 0.9984 221125_WJC_METTL3_EV_vs_WT_F08.05463.05463.3 0.00171 Sep-36 K.TQLSQAEVHK.V "tr|A0A140TA76|A0A140TA76_HUMAN,tr|K7EMZ9|K7EMZ9_HUMAN" 2 1139.5935 0.52 111475 5463 3 1139.596093 380.8718 Protein LSM14 homolog A (Fragment) OS=Homo sapiens OX=9606 GN=LSM14A PE=1 SV=1 6.41 1512.8 - 2.43E+06 - - - 2.2868 - 1.952 0.276 - 119.9 1 2 0 0.0026 10 0 0 0 3.21E+07 6.22E+07 - - - 3.5698 0.9976 221125_WJC_METTL3_EV_vs_WT_F08.05464.05464.2 0.0578 13/20 K.FK[136.11]QESTVATER[166.11].Q sp|Q9H307|PININ_HUMAN 1 1312.6742 1.22 111476 5464 2 1312.673933 657.3444 Pinin OS=Homo sapiens OX=9606 GN=PNN PE=1 SV=5 6.14 1512.9 - 1.38E+06 - - - -0.2034 - 2.153 0.387 - 425.9 1 2 1 -0.0003 11 0 0 0 3.30E+07 2.71E+07 - - - 3.9738 0.9998 221125_WJC_METTL3_EV_vs_WT_F08.05466.05466.2 7.31E-05 14/16 R.KAQC[160.03]PIVER.L "sp|P46782|RS5_HUMAN,tr|M0R0F0|M0R0F0_HUMAN,tr|M0R0R2|M0R0R2_HUMAN" 3 1099.5808 0.82 111478 5466 2 1099.581627 550.7977 40S ribosomal protein S5 OS=Homo sapiens OX=9606 GN=RPS5 PE=1 SV=4 8.22 1513.2 - 882564 - - - 0.7394 - 2.29 0.419 - 786 1 2 0 0.0008 9 0 0 0 1.16E+07 1.41E+07 - - - 4.5325 0.9999 221125_WJC_METTL3_EV_vs_WT_F08.05467.05467.2 0.000222 24-Oct K.GALTTQDENGQTK.R "sp|Q9ULX6|AKP8L_HUMAN,tr|A0A7P0T9N5|A0A7P0T9N5_HUMAN,tr|A0A7P0TAD3|A0A7P0TAD3_HUMAN,tr|V9GZ50|V9GZ50_HUMAN,tr|A0A7P0TBP0|A0A7P0TBP0_HUMAN,tr|A0A7P0TAJ5|A0A7P0TAJ5_HUMAN,tr|A0A7P0TAE3|A0A7P0TAE3_HUMAN" 7 1361.6423 1.29 111479 5467 2 1361.641898 681.8284 A-kinase anchor protein 8-like OS=Homo sapiens OX=9606 GN=AKAP8L PE=1 SV=4 4.37 1513.3 - 665970 - - - -0.2857 - 2.252 0.466 - 344.9 1 2 0 -0.0004 13 0 0 0 3.31E+06 2.56E+06 - - - 4.5663 0.9995 221125_WJC_METTL3_EV_vs_WT_F08.05468.05468.3 6.28E-06 14/48 R.AAGEQEKLEATNR.Y "sp|O60231|DHX16_HUMAN,tr|A0A140T947|A0A140T947_HUMAN,tr|A2AB15|A2AB15_HUMAN" 3 1415.7005 1.81 111480 5468 3 1415.70279 472.9074 Pre-mRNA-splicing factor ATP-dependent RNA helicase DHX16 OS=Homo sapiens OX=9606 GN=DHX16 PE=1 SV=2 4.79 1513.4 - 628259 - - - 1.6381 - 2.381 0.421 - 306 1 2 1 0.0023 13 0 0 0 1.98E+07 1.09E+07 - - - 5.5852 1 221125_WJC_METTL3_EV_vs_WT_F08.05469.05469.3 3.25E-07 Dec-44 R.C[160.03]EMSEHPSQTVR.K sp|Q32MZ4|LRRF1_HUMAN 1 1459.6184 0.61 111481 5469 3 1459.617417 487.5467 Leucine-rich repeat flightless-interacting protein 1 OS=Homo sapiens OX=9606 GN=LRRFIP1 PE=1 SV=2 5.4 1513.5 - 515901 - - - -0.6721 - 2.242 0.554 - 172.4 1 2 0 -0.001 12 0 0 0 4.78E+06 7.83E+06 - - - 6.9542 0.9908 221125_WJC_METTL3_EV_vs_WT_F08.05472.05472.2 3.41E-05 18-Oct K.TQLSQAEVHK.V "tr|A0A140TA76|A0A140TA76_HUMAN,tr|K7EMZ9|K7EMZ9_HUMAN" 2 1139.5935 0.95 111484 5472 2 1139.601373 570.804 Protein LSM14 homolog A (Fragment) OS=Homo sapiens OX=9606 GN=LSM14A PE=1 SV=1 6.41 1513.9 - 240025 - - - 6.92 - 2.045 0.486 - 341 1 2 0 0.0079 10 0 0 0 4.79E+06 5.07E+06 - - - 4.625 0.9999 221125_WJC_METTL3_EV_vs_WT_F08.05477.05477.3 3.21E-05 Dec-36 K.TQLSQAEVHK[136.11].V "tr|A0A140TA76|A0A140TA76_HUMAN,tr|K7EMZ9|K7EMZ9_HUMAN" 2 1147.6077 0.86 111487 5477 3 1147.608888 383.5432 Protein LSM14 homolog A (Fragment) OS=Homo sapiens OX=9606 GN=LSM14A PE=1 SV=1 6.41 1514.5 - 7.98E+06 - - - 1.0465 - 2.238 0.411 - 278.8 1 2 0 0.0012 10 0 0 0 3.04E+07 3.52E+07 - - - 5.4746 0.8797 221125_WJC_METTL3_EV_vs_WT_F08.05478.05478.3 0.361 Jul-40 K.FKQESTVATER.Q sp|Q9H307|PININ_HUMAN 1 1294.6517 1.56 111488 5478 3 1294.652751 432.5579 Pinin OS=Homo sapiens OX=9606 GN=PNN PE=1 SV=5 6.14 1514.6 - 4.09E+06 - - - 0.7886 - 1.507 0.145 - 87.1 2 2 1 0.001 11 0 0 0 2.47E+08 1.58E+08 - - - 1.1821 0.9875 221125_WJC_METTL3_EV_vs_WT_F08.05480.05480.3 0.0385 Sep-40 R.QVDQLTNDKAR.V "sp|P08670|VIME_HUMAN,tr|B0YJC4|B0YJC4_HUMAN" 2 1286.6579 0.35 111490 5480 3 1286.661991 429.8932 Vimentin OS=Homo sapiens OX=9606 GN=VIM PE=1 SV=4 5.96 1514.7 - 3.33E+06 - - - 3.1967 - 1.746 0.317 - 114.9 1 2 1 0.0041 11 0 0 0 1.90E+07 5.49E+07 - - - 3.6564 0.9958 221125_WJC_METTL3_EV_vs_WT_F08.05482.05482.3 0.000144 13/36 A.HQLHPGLVQR[166.11].M "sp|Q9NRA8|4ET_HUMAN,tr|B1AKL4|B1AKL4_HUMAN" 2 1193.6657 1.01 111492 5482 3 1193.666391 398.8958 Eukaryotic translation initiation factor 4E transporter OS=Homo sapiens OX=9606 GN=EIF4ENIF1 PE=1 SV=2 9.76 1514.8 - 1.89E+06 - - - 0.5839 - 2.634 0.43 - 266.9 1 1 0 0.0007 10 0 0 0 1.45E+07 1.44E+07 - - - 6.1623 0.9998 221125_WJC_METTL3_EV_vs_WT_F08.05483.05483.3 0.00258 15/48 R.AAGEQEK[136.11]LEATNR[166.11].Y "sp|O60231|DHX16_HUMAN,tr|A0A140T947|A0A140T947_HUMAN,tr|A2AB15|A2AB15_HUMAN" 3 1433.7229 1.81 111493 5483 3 1433.72475 478.9149 Pre-mRNA-splicing factor ATP-dependent RNA helicase DHX16 OS=Homo sapiens OX=9606 GN=DHX16 PE=1 SV=2 4.79 1514.8 - 1.64E+06 - - - 1.2618 - 2.82 0.471 - 393.1 1 2 1 0.0018 13 0 0 0 1.98E+07 1.09E+07 - - - 6.6016 0.9999 221125_WJC_METTL3_EV_vs_WT_F08.05485.05485.2 5.16E-10 14/26 R.ATSSSSGSLSATGR.L sp|Q03252|LMNB2_HUMAN 1 1267.6004 1.12 111495 5485 2 1267.600965 634.8075 Lamin-B2 OS=Homo sapiens OX=9606 GN=LMNB2 PE=1 SV=4 9.79 1515 - 1.56E+06 - - - 0.4284 - 2.985 0.527 - 888.3 1 2 0 0.0005 14 0 0 0 3.43E+07 3.08E+07 - - - 5.6776 1 221125_WJC_METTL3_EV_vs_WT_F08.05486.05486.2 0.0269 15/26 R.ATSSSSGSLSATGR[166.11].L sp|Q03252|LMNB2_HUMAN 1 1277.6087 1.11 111496 5486 2 1277.609101 639.8116 Lamin-B2 OS=Homo sapiens OX=9606 GN=LMNB2 PE=1 SV=4 9.79 1515 - 1.50E+06 - - - 0.3201 - 2.98 0.541 - 1047 1 2 0 0.0004 14 0 0 0 3.43E+07 3.10E+07 - - - 5.7768 0.9997 221125_WJC_METTL3_EV_vs_WT_F08.05487.05487.2 0.00208 16-Sep R.K[136.11]AQC[160.03]PIVER[166.11].L "sp|P46782|RS5_HUMAN,tr|M0R0F0|M0R0F0_HUMAN,tr|M0R0R2|M0R0R2_HUMAN" 3 1117.6033 0.83 111497 5487 2 1117.604718 559.8089 40S ribosomal protein S5 OS=Homo sapiens OX=9606 GN=RPS5 PE=1 SV=4 8.22 1515.1 - 1.49E+06 - - - 1.2831 - 2.117 0.373 - 332.1 1 2 0 0.0014 9 0 0 0 1.16E+07 1.40E+07 - - - 3.9653 1 221125_WJC_METTL3_EV_vs_WT_F08.05488.05488.3 3.15E-06 14/44 K.HLLGAEHGDEPR[166.11].H "sp|Q9BV38|WDR18_HUMAN,tr|U3KQC1|U3KQC1_HUMAN,tr|A0A0A0MQU0|A0A0A0MQU0_HUMAN,tr|K7EIR0|K7EIR0_HUMAN" 4 1339.6508 1.31 111498 5488 3 1339.652831 447.5576 WD repeat-containing protein 18 OS=Homo sapiens OX=9606 GN=WDR18 PE=1 SV=2 5.27 1515.2 - 1.25E+06 - - - 1.4922 - 2.456 0.509 - 187.1 1 2 0 0.002 12 0 0 0 1.33E+08 1.01E+08 - - - 6.7049 0.9997 221125_WJC_METTL3_EV_vs_WT_F08.05489.05489.2 1.45E-07 13/18 R.SHQNASSIIK.C "sp|O75970|MPDZ_HUMAN,tr|B7ZB24|B7ZB24_HUMAN,tr|H0YGQ3|H0YGQ3_HUMAN,tr|F5H1U9|F5H1U9_HUMAN" 4 1083.5673 0.63 111499 5489 2 1083.570378 542.7909 Multiple PDZ domain protein OS=Homo sapiens OX=9606 GN=MPDZ PE=1 SV=2 8.49 1515.3 - 953200 - - - 2.8665 - 2.562 0.548 - 592.1 1 2 0 0.0031 10 0 0 0 4.81E+06 7.64E+06 - - - 5.7136 0.9998 221125_WJC_METTL3_EV_vs_WT_F08.05490.05490.2 0.000137 18-Nov R.K[136.11]QDSGHLDLR[166.11].N "sp|Q86U44|MTA70_HUMAN,tr|B4E349|B4E349_HUMAN,tr|F5H6D8|F5H6D8_HUMAN,tr|B4DTN4|B4DTN4_HUMAN" 4 1185.6221 0.001 111500 5490 2 1185.622947 593.8183 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 6.75 1515.4 - 655514 - - - 0.7102 - 2.088 0.486 - 401.1 1 2 0 0.0008 10 0 0 0 0.00E+00 2.61E+06 - - - 4.6853 0.9995 221125_WJC_METTL3_EV_vs_WT_F08.05491.05491.2 0.00051 20-Oct R.SFSTSAQNNAK.V sp|P40926|MDHM_HUMAN 1 1153.5364 1.97 111501 5491 2 1153.535296 577.7755 "Malate dehydrogenase, mitochondrial OS=Homo sapiens OX=9606 GN=MDH2 PE=1 SV=3" 8.47 1515.5 - 585142 - - - -0.9276 - 1.581 0.386 - 200.4 1 2 0 -0.0011 11 0 0 0 5.93E+06 3.01E+06 - - - 3.1308 0.9998 221125_WJC_METTL3_EV_vs_WT_F08.05493.05493.2 3.41E-05 22-Dec K.SEISENTDASGK[136.11].L "sp|Q9UHB6|LIMA1_HUMAN,tr|F8VRN8|F8VRN8_HUMAN,tr|F8VQE1|F8VQE1_HUMAN" 3 1244.5612 0.92 111503 5493 2 1244.559309 623.2879 LIM domain and actin-binding protein 1 OS=Homo sapiens OX=9606 GN=LIMA1 PE=1 SV=1 4.14 1515.8 - 358427 - - - -1.5114 - 2.196 0.454 - 420.9 1 2 0 -0.0019 12 0 0 0 1.23E+07 1.35E+07 - - - 4.4634 0.9988 221125_WJC_METTL3_EV_vs_WT_F08.05499.05499.2 0.00425 16-Jul R.RNDLDDPER.G sp|Q15393|SF3B3_HUMAN 1 1128.516 3.36 111508 5499 2 1128.518748 565.2653 Splicing factor 3B subunit 3 OS=Homo sapiens OX=9606 GN=SF3B3 PE=1 SV=4 4.23 1516.5 - 189974 - - - 2.467 - 1.605 0.39 - 178.1 1 2 0 0.0028 9 0 0 0 3.07E+06 9.12E+05 - - - 3.2894 0.9999 221125_WJC_METTL3_EV_vs_WT_F08.05500.05500.3 1.32E-05 13/40 K.QRAEVLQSTQR.F "sp|Q9Y520|PRC2C_HUMAN,tr|E7EPN9|E7EPN9_HUMAN,tr|H7C5N8|H7C5N8_HUMAN,tr|A0A2R8YET2|A0A2R8YET2_HUMAN" 4 1314.7004 2.59 111509 5500 3 1314.700684 439.2407 Protein PRRC2C OS=Homo sapiens OX=9606 GN=PRRC2C PE=1 SV=4 9.6 1516.6 - 3.81E+06 - - - 0.2077 - 2.528 0.487 - 350.3 1 2 1 0.0003 11 0 0 0 1.10E+07 4.25E+06 - - - 6.6042 0.9083 221125_WJC_METTL3_EV_vs_WT_F08.05501.05501.3 0.0743 Aug-32 R.GYFEHREDR.R "sp|Q9BUJ2|HNRL1_HUMAN,tr|M0R0K8|M0R0K8_HUMAN,tr|M0QYZ0|M0QYZ0_HUMAN,tr|A0A0A0MRA5|A0A0A0MRA5_HUMAN,tr|M0QZV6|M0QZV6_HUMAN,tr|M0R3F1|M0R3F1_HUMAN,tr|B7Z4B8|B7Z4B8_HUMAN,tr|M0QYI8|M0QYI8_HUMAN" 8 1207.537 0.31 111510 5501 3 1207.537318 403.5196 Heterogeneous nuclear ribonucleoprotein U-like protein 1 OS=Homo sapiens OX=9606 GN=HNRNPUL1 PE=1 SV=2 5.45 1516.6 - 3.49E+06 - - - 0.2352 - 1.235 0.195 - 117.7 1 2 1 0.0003 9 0 0 0 1.17E+07 3.76E+07 - - - 1.3501 0.9985 221125_WJC_METTL3_EV_vs_WT_F08.05502.05502.3 0.0227 Oct-36 K.LYAVHQEGNK[136.11].N "sp|P50990|TCPQ_HUMAN,tr|H7C2U0|H7C2U0_HUMAN" 2 1165.5971 0.46 111511 5502 3 1165.597817 389.5397 T-complex protein 1 subunit theta OS=Homo sapiens OX=9606 GN=CCT8 PE=1 SV=4 6.75 1516.7 - 3.35E+06 - - - 0.5963 - 1.682 0.268 - 112 1 2 0 0.0007 10 0 0 0 4.84E+06 1.05E+07 - - - 3.0463 0.9999 221125_WJC_METTL3_EV_vs_WT_F08.05505.05505.2 1.50E-05 26-Dec R.VSGQPQSVTASSDK.A "sp|Q8N6T3|ARFG1_HUMAN,tr|F8VWH9|F8VWH9_HUMAN,tr|E5RHT6|E5RHT6_HUMAN,tr|F8W1U7|F8W1U7_HUMAN,tr|E5RHC5|E5RHC5_HUMAN" 5 1389.6736 1.6 111514 5505 2 1389.67195 695.8441 ADP-ribosylation factor GTPase-activating protein 1 OS=Homo sapiens OX=9606 GN=ARFGAP1 PE=1 SV=2 5.81 1516.8 - 2.58E+06 - - - -1.178 - 2.028 0.566 - 338.4 1 2 0 -0.0016 14 0 0 0 5.69E+07 3.56E+07 - - - 4.9953 0.9999 221125_WJC_METTL3_EV_vs_WT_F08.05507.05507.2 1.08E-05 13/22 K.SEISENTDASGK.L "sp|Q9UHB6|LIMA1_HUMAN,tr|F8VRN8|F8VRN8_HUMAN,tr|F8VQE1|F8VQE1_HUMAN" 3 1236.547 0.92 111516 5507 2 1236.546959 619.2808 LIM domain and actin-binding protein 1 OS=Homo sapiens OX=9606 GN=LIMA1 PE=1 SV=1 4.14 1516.9 - 1.96E+06 - - - -0.0251 - 2.318 0.472 - 560.2 1 2 0 0 12 0 0 0 1.23E+07 1.35E+07 - - - 4.7392 0.9995 221125_WJC_METTL3_EV_vs_WT_F08.05508.05508.2 0.0487 16-Dec K.RQVQNLVNK.S sp|P15924|DESP_HUMAN 1 1097.6305 59.03 111517 5508 2 1097.630819 549.8225 Desmoplakin OS=Homo sapiens OX=9606 GN=DSP PE=1 SV=3 11 1517.1 - 1.56E+06 - - - 0.2533 - 2.017 0.275 - 665.7 1 2 0 0.0003 9 0 0 0 5.06E+06 8.57E+04 - - - 3.1019 0.9999 221125_WJC_METTL3_EV_vs_WT_F08.05512.05512.2 9.55E-06 18-Dec R.EANQQQQFNR.N "sp|Q13813|SPTN1_HUMAN,tr|A0A0D9SF54|A0A0D9SF54_HUMAN,tr|A0A0D9SGF6|A0A0D9SGF6_HUMAN" 3 1261.58 2.1 111521 5512 2 1261.580603 631.7973 "Spectrin alpha chain, non-erythrocytic 1 OS=Homo sapiens OX=9606 GN=SPTAN1 PE=1 SV=3" 6.1 1517.4 - 699056 - - - 0.5081 - 2.322 0.522 - 948.3 1 2 0 0.0006 10 0 0 0 7.35E+07 3.51E+07 - - - 5.2478 0.9996 221125_WJC_METTL3_EV_vs_WT_F08.05514.05514.2 0.00204 18-Oct R.QTHTVDSLSR[166.11].L "sp|Q96T88|UHRF1_HUMAN,tr|A0A087WTW0|A0A087WTW0_HUMAN,tr|A0A087WVR3|A0A087WVR3_HUMAN" 3 1152.5763 0.88 111523 5514 2 1152.577395 577.2954 E3 ubiquitin-protein ligase UHRF1 OS=Homo sapiens OX=9606 GN=UHRF1 PE=1 SV=1 6.74 1517.6 - 615892 - - - 0.9761 - 1.763 0.416 - 350 1 2 0 0.0011 10 0 0 0 2.47E+06 2.80E+06 - - - 3.6959 0.9861 221125_WJC_METTL3_EV_vs_WT_F08.05517.05517.2 4.08E-05 14/20 K.QRAEVLQSTQR.F "sp|Q9Y520|PRC2C_HUMAN,tr|E7EPN9|E7EPN9_HUMAN,tr|H7C5N8|H7C5N8_HUMAN,tr|A0A2R8YET2|A0A2R8YET2_HUMAN" 4 1314.7004 -1 111526 5517 2 1314.70593 658.3575 Protein PRRC2C OS=Homo sapiens OX=9606 GN=PRRC2C PE=1 SV=4 9.6 1518 - 453233 - - - 4.1979 - 2.123 0.527 - 246.5 1 2 1 0.0055 11 0 0 0 0.00E+00 0.00E+00 - - - 4.9683 0.9943 221125_WJC_METTL3_EV_vs_WT_F08.05519.05519.2 0.212 20-Jul K.AQNAESSLQQK.N "sp|Q96T51|RUFY1_HUMAN,tr|H0YA47|H0YA47_HUMAN,tr|H0YAC8|H0YAC8_HUMAN" 3 1202.5891 -1 111527 5519 2 1202.591818 602.3018 RUN and FYVE domain-containing protein 1 OS=Homo sapiens OX=9606 GN=RUFY1 PE=1 SV=2 6.05 1518.3 - 329852 - - - 2.236 - 1.47 0.225 - 148.5 1 2 0 0.0027 11 0 0 0 0.00E+00 0.00E+00 - - - 1.7442 0.9989 221125_WJC_METTL3_EV_vs_WT_F08.05520.05520.2 0.000103 22-Oct R.GPQVQQPPPSNR.F "sp|Q15436|SC23A_HUMAN,tr|F5H365|F5H365_HUMAN" 2 1303.6633 0.15 111528 5520 2 1303.658461 652.8389 Protein transport protein Sec23A OS=Homo sapiens OX=9606 GN=SEC23A PE=1 SV=2 9.75 1518.5 - 174341 - - - -3.7095 - 2.148 0.472 - 301 1 2 0 -0.0048 12 0 0 0 2.52E+06 1.71E+07 - - - 4.5373 0.9999 221125_WJC_METTL3_EV_vs_WT_F08.05521.05521.3 5.60E-06 Dec-40 R.VDSFHESTEGK.V "sp|Q8WWY3|PRP31_HUMAN,tr|E7EVX8|E7EVX8_HUMAN" 2 1234.5466 2.43 111529 5521 3 1234.547045 412.5228 U4\U6 small nuclear ribonucleoprotein Prp31 OS=Homo sapiens OX=9606 GN=PRPF31 PE=1 SV=2 4.65 1518.5 - 6.36E+06 - - - 0.3637 - 2.353 0.404 - 296 1 2 0 0.0004 11 0 0 0 1.20E+08 4.93E+07 - - - 5.4749 0.9997 221125_WJC_METTL3_EV_vs_WT_F08.05524.05524.3 0.000713 15/40 K.KPPPSKEELLK.L "sp|P78344|IF4G2_HUMAN,tr|E9PKF8|E9PKF8_HUMAN,tr|H0Y3P2|H0Y3P2_HUMAN,tr|D3DQV9|D3DQV9_HUMAN" 4 1264.7391 2.69 111532 5524 3 1264.73924 422.587 Eukaryotic translation initiation factor 4 gamma 2 OS=Homo sapiens OX=9606 GN=EIF4G2 PE=1 SV=1 8.5 1518.6 - 4.62E+06 - - - 0.1202 - 2.695 0.368 - 370.5 1 2 1 0.0002 11 0 0 0 9.56E+07 3.56E+07 - - - 5.4592 0.9998 221125_WJC_METTL3_EV_vs_WT_F08.05526.05526.3 0.0197 Sep-36 R.QTHTVDSLSR.L "sp|Q96T88|UHRF1_HUMAN,tr|A0A087WTW0|A0A087WTW0_HUMAN,tr|A0A087WVR3|A0A087WVR3_HUMAN" 3 1142.568 0.61 111534 5526 3 1142.568266 381.8633 E3 ubiquitin-protein ligase UHRF1 OS=Homo sapiens OX=9606 GN=UHRF1 PE=1 SV=1 6.74 1518.7 - 4.01E+06 - - - 0.2328 - 2 0.346 - 189.4 1 2 0 0.0003 10 0 0 0 1.65E+07 2.70E+07 - - - 4.4218 1 221125_WJC_METTL3_EV_vs_WT_F08.05527.05527.3 1.73E-05 Nov-40 R.VDSFHESTEGK[136.11].V "sp|Q8WWY3|PRP31_HUMAN,tr|E7EVX8|E7EVX8_HUMAN" 2 1242.5608 2.41 111535 5527 3 1242.561786 415.1942 U4\U6 small nuclear ribonucleoprotein Prp31 OS=Homo sapiens OX=9606 GN=PRPF31 PE=1 SV=2 4.65 1518.8 - 3.02E+06 - - - 0.7967 - 2.182 0.496 - 203.6 1 2 0 0.001 11 0 0 0 1.20E+08 4.97E+07 - - - 6.2862 0.9997 221125_WJC_METTL3_EV_vs_WT_F08.05529.05529.3 0.00388 Dec-40 K.K[136.11]PPPSK[136.11]EELLK[136.11].L "sp|P78344|IF4G2_HUMAN,tr|E9PKF8|E9PKF8_HUMAN,tr|H0Y3P2|H0Y3P2_HUMAN,tr|D3DQV9|D3DQV9_HUMAN" 4 1288.7817 2.69 111537 5529 3 1288.782102 430.6012 Eukaryotic translation initiation factor 4 gamma 2 OS=Homo sapiens OX=9606 GN=EIF4G2 PE=1 SV=1 8.5 1518.9 - 2.30E+06 - - - 0.3212 - 2.473 0.409 - 166.2 1 2 1 0.0004 11 0 0 0 9.56E+07 3.56E+07 - - - 5.672 0.9997 221125_WJC_METTL3_EV_vs_WT_F08.05535.05535.3 0.000124 Dec-44 R.TVASIK[136.11]NDPPSR[166.11].D "sp|O00139|KIF2A_HUMAN,tr|D6R9M0|D6R9M0_HUMAN,tr|A0A6Q8PFA6|A0A6Q8PFA6_HUMAN,tr|A0A6Q8PGG1|A0A6Q8PGG1_HUMAN,tr|A0A6Q8PGH7|A0A6Q8PGH7_HUMAN,tr|A0A6Q8PG37|A0A6Q8PG37_HUMAN,tr|A0A6Q8PH57|A0A6Q8PH57_HUMAN" 7 1301.7058 1.47 111543 5535 3 1301.706768 434.9092 Kinesin-like protein KIF2A OS=Homo sapiens OX=9606 GN=KIF2A PE=1 SV=3 8.41 1519.4 - 1.08E+06 - - - 0.7175 - 2.041 0.466 - 136.3 1 2 1 0.0009 12 0 0 0 1.04E+07 7.09E+06 - - - 5.7127 0.9989 221125_WJC_METTL3_EV_vs_WT_F08.05537.05537.3 9.83E-06 24/56 F.LNSTAGASGGAYEHR[166.11].Y "sp|P31943|HNRH1_HUMAN,tr|H0YB39|H0YB39_HUMAN,tr|G8JLB6|G8JLB6_HUMAN" 3 1499.6992 1.91 111545 5537 3 1499.700576 500.907 Heterogeneous nuclear ribonucleoprotein H OS=Homo sapiens OX=9606 GN=HNRNPH1 PE=1 SV=4 6.75 1519.5 - 777815 - - - 0.8915 - 4.041 0.547 - 1160.7 1 1 0 0.0013 15 0 0 0 1.94E+07 1.01E+07 - - - 8.2821 0.9875 221125_WJC_METTL3_EV_vs_WT_F08.05538.05538.2 2.13 18-Aug R.QTHTVDSLSR.L "sp|Q96T88|UHRF1_HUMAN,tr|A0A087WTW0|A0A087WTW0_HUMAN,tr|A0A087WVR3|A0A087WVR3_HUMAN" 3 1142.568 0.88 111546 5538 2 1142.567593 572.2913 E3 ubiquitin-protein ligase UHRF1 OS=Homo sapiens OX=9606 GN=UHRF1 PE=1 SV=1 6.74 1519.7 - 756561 - - - -0.3562 - 1.204 0.124 - 161.5 1 2 0 -0.0004 10 0 0 0 2.47E+06 2.80E+06 - - - 0.4749 1 221125_WJC_METTL3_EV_vs_WT_F08.05540.05540.2 3.59E-06 13/18 V.DSFHESTEGK.V "sp|Q8WWY3|PRP31_HUMAN,tr|E7EVX8|E7EVX8_HUMAN" 2 1135.4782 2.59 111547 5540 2 1135.479091 568.7464 U4\U6 small nuclear ribonucleoprotein Prp31 OS=Homo sapiens OX=9606 GN=PRPF31 PE=1 SV=2 4.65 1519.9 - 1.80E+06 - - - 0.8005 - 2.521 0.612 - 708.9 1 1 0 0.0009 10 0 0 0 9.30E+06 3.60E+06 - - - 6.1419 0.9997 221125_WJC_METTL3_EV_vs_WT_F08.05542.05542.3 0.000314 14/36 R.LRAEIDNVKK.Q "sp|P13647|K2C5_HUMAN,tr|H0YI76|H0YI76_HUMAN" 2 1184.6877 1260.74 111549 5542 3 1184.689571 395.9032 "Keratin, type II cytoskeletal 5 OS=Homo sapiens OX=9606 GN=KRT5 PE=1 SV=3" 8.59 1520.1 - 7.71E+06 - - - 1.5616 - 2.601 0.412 - 281 1 2 1 0.0019 10 0 0 0 5.78E+08 4.59E+05 - - - 5.9245 1 221125_WJC_METTL3_EV_vs_WT_F08.05545.05545.2 8.32E-07 13/26 K.AESEEMETSQAGSK[136.11].D "sp|P34932|HSP74_HUMAN,tr|A0A087WYC1|A0A087WYC1_HUMAN" 2 1490.6286 0.001 111552 5545 2 1490.628051 746.3216 Heat shock 70 kDa protein 4 OS=Homo sapiens OX=9606 GN=HSPA4 PE=1 SV=4 4.09 1520.2 - 1.09E+06 - - - -0.3804 - 2.912 0.696 - 631.4 1 2 0 -0.0006 14 0 0 0 0.00E+00 1.01E+07 - - - 6.8637 1 221125_WJC_METTL3_EV_vs_WT_F08.05547.05547.2 0.000665 17/30 K.GVPAGNSDTEGGQPGR.K "sp|Q9UKV3|ACINU_HUMAN,tr|G3V3B0|G3V3B0_HUMAN,tr|S4R3H4|S4R3H4_HUMAN,tr|E7EQT4|E7EQT4_HUMAN,tr|G3V3T3|G3V3T3_HUMAN" 5 1497.6808 1.56 111554 5547 2 1497.680337 749.8477 Apoptotic chromatin condensation inducer in the nucleus OS=Homo sapiens OX=9606 GN=ACIN1 PE=1 SV=2 4.37 1520.5 - 715137 - - - -0.3078 - 2.907 0.637 - 779.6 1 2 0 -0.0005 16 0 0 0 6.05E+07 3.89E+07 - - - 6.3693 1 221125_WJC_METTL3_EV_vs_WT_F08.05548.05548.2 1.54E-07 14/30 K.GVPAGNSDTEGGQPGR[166.11].K "sp|Q9UKV3|ACINU_HUMAN,tr|G3V3B0|G3V3B0_HUMAN,tr|S4R3H4|S4R3H4_HUMAN,tr|E7EQT4|E7EQT4_HUMAN,tr|G3V3T3|G3V3T3_HUMAN" 5 1507.6891 1.56 111555 5548 2 1507.688273 754.8518 Apoptotic chromatin condensation inducer in the nucleus OS=Homo sapiens OX=9606 GN=ACIN1 PE=1 SV=2 4.37 1520.6 - 606574 - - - -0.5273 - 2.494 0.66 - 466.8 1 2 0 -0.0008 16 0 0 0 6.05E+07 3.89E+07 - - - 6.1623 0.9998 221125_WJC_METTL3_EV_vs_WT_F08.05550.05550.2 0.000257 20-Dec K.TQETLSQAGQK.T "sp|O43399|TPD54_HUMAN,tr|A0A087WYR3|A0A087WYR3_HUMAN" 2 1189.5939 1.42 111557 5550 2 1189.591793 595.8042 Tumor protein D54 OS=Homo sapiens OX=9606 GN=TPD52L2 PE=1 SV=2 5.66 1520.9 - 504697 - - - -1.7552 - 2.419 0.535 - 518.9 1 2 0 -0.0021 11 0 0 0 1.74E+07 1.23E+07 - - - 5.3815 0.9976 221125_WJC_METTL3_EV_vs_WT_F08.05551.05551.2 0.0267 13/18 R.LRAEIDNVKK.Q "sp|P13647|K2C5_HUMAN,tr|H0YI76|H0YI76_HUMAN" 2 1184.6877 999 111558 5551 2 1184.68834 593.3511 "Keratin, type II cytoskeletal 5 OS=Homo sapiens OX=9606 GN=KRT5 PE=1 SV=3" 8.59 1521 - 448516 - - - 0.5225 - 2.229 0.381 - 469.1 1 2 1 0.0006 10 0 0 0 3.76E+07 0.00E+00 - - - 4.0923 0.9999 221125_WJC_METTL3_EV_vs_WT_F08.05554.05554.2 1.22E-05 26-Sep R.VVDESDETENQEEK[136.11].A sp|O75717|WDHD1_HUMAN 1 1657.7046 -1 111561 5554 2 1657.702299 829.8596 WD repeat and HMG-box DNA-binding protein 1 OS=Homo sapiens OX=9606 GN=WDHD1 PE=1 SV=1 3.71 1521.4 - 310941 - - - -1.3995 - 2.019 0.656 - 174 1 2 0 -0.0023 14 0 0 0 0.00E+00 0.00E+00 - - - 5.6486 0.9999 221125_WJC_METTL3_EV_vs_WT_F08.05555.05555.2 8.14E-08 30-Jul R.AGAPADQGAEAADNQR.E sp|Q9H0W5|CCDC8_HUMAN 1 1540.6866 2 111562 5555 2 1540.688274 771.3506 Coiled-coil domain-containing protein 8 OS=Homo sapiens OX=9606 GN=CCDC8 PE=1 SV=2 4.03 1521.6 - 295961 - - - 1.0787 - 1.957 0.645 - 61.4 1 2 0 0.0017 16 0 0 0 1.55E+06 7.77E+05 - - - 5.4551 0.9997 221125_WJC_METTL3_EV_vs_WT_F08.05556.05556.2 0.00953 22-Oct K.AGSGNSSQPSLR.E sp|Q68D10|SPT2_HUMAN 1 1159.5582 1.07 111563 5556 2 1159.557011 580.7864 Protein SPT2 homolog OS=Homo sapiens OX=9606 GN=SPTY2D1 PE=1 SV=3 9.79 1521.7 - 241278 - - - -0.9943 - 2.099 0.392 - 333.6 1 2 0 -0.0012 12 0 0 0 2.22E+06 2.08E+06 - - - 3.8869 0.9998 221125_WJC_METTL3_EV_vs_WT_F08.05558.05558.2 0.00568 16-Nov K.K[136.11]SLESINSR[166.11].L "sp|P62888|RL30_HUMAN,tr|E5RJH3|E5RJH3_HUMAN,tr|E5RI99|E5RI99_HUMAN,tr|A0A0C4DH44|A0A0C4DH44_HUMAN" 4 1050.5788 1.16 111565 5558 2 1050.579283 526.2967 60S ribosomal protein L30 OS=Homo sapiens OX=9606 GN=RPL30 PE=1 SV=2 8.75 1521.9 - 154421 - - - 0.4188 - 2.156 0.374 - 392.9 1 2 0 0.0004 9 0 0 0 1.43E+07 1.23E+07 - - - 4.0258 0.9635 221125_WJC_METTL3_EV_vs_WT_F08.05562.05562.2 2.3 12-May K.EQSIVEK[136.11].F "sp|Q86U44|MTA70_HUMAN,tr|H0YFV6|H0YFV6_HUMAN" 2 839.448 0.02 111567 5562 2 839.447 420.7313 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 4.53 1522.5 - 4.88E+07 - - - -1.1889 - 1.263 0.021 - 198.5 1 2 0 -0.001 7 0 0 0 5.27E+06 2.65E+08 - - - -0.0644 1 221125_WJC_METTL3_EV_vs_WT_F08.05564.05564.3 0.000826 Nov-44 R.K[136.11]MDETDASSAVK[136.11].V "sp|Q13148|TADBP_HUMAN,tr|A0A087WX29|A0A087WX29_HUMAN,tr|G3V162|G3V162_HUMAN,tr|A0A087WYY0|A0A087WYY0_HUMAN,tr|K7EN94|K7EN94_HUMAN,tr|A0A0A0N0M3|A0A0A0N0M3_HUMAN,tr|B1AKP7|B1AKP7_HUMAN,tr|K7EJM5|K7EJM5_HUMAN,tr|A0A087X260|A0A087X260_HUMAN" 9 1296.6202 1.51 111569 5564 3 1296.619258 433.214 TAR DNA-binding protein 43 OS=Homo sapiens OX=9606 GN=TARDBP PE=1 SV=1 4.56 1522.6 - 3.46E+06 - - - -0.7512 - 2.386 0.553 - 212.4 1 2 0 -0.001 12 0 0 0 8.56E+07 5.68E+07 - - - 7.1156 1 221125_WJC_METTL3_EV_vs_WT_F08.05565.05565.2 3.97E-09 20/22 R.KMDETDASSAVK.V "sp|Q13148|TADBP_HUMAN,tr|A0A087WX29|A0A087WX29_HUMAN,tr|G3V162|G3V162_HUMAN,tr|A0A087WYY0|A0A087WYY0_HUMAN,tr|K7EN94|K7EN94_HUMAN,tr|A0A0A0N0M3|A0A0A0N0M3_HUMAN,tr|B1AKP7|B1AKP7_HUMAN,tr|K7EJM5|K7EJM5_HUMAN,tr|A0A087X260|A0A087X260_HUMAN" 9 1280.5918 1.39 111570 5565 2 1280.591156 641.3032 TAR DNA-binding protein 43 OS=Homo sapiens OX=9606 GN=TARDBP PE=1 SV=1 4.56 1522.6 - 2.68E+06 - - - -0.5279 - 3.826 0.671 - 1283.5 1 2 0 -0.0007 12 0 0 0 4.90E+07 3.52E+07 - - - 7.5273 0.9999 221125_WJC_METTL3_EV_vs_WT_F08.05566.05566.2 2.26E-06 14/20 K.TQETLSQAGQK[136.11].T "sp|O43399|TPD54_HUMAN,tr|A0A087WYR3|A0A087WYR3_HUMAN" 2 1197.6081 1.42 111571 5566 2 1197.60727 599.8113 Tumor protein D54 OS=Homo sapiens OX=9606 GN=TPD52L2 PE=1 SV=2 5.66 1522.7 - 2.31E+06 - - - -0.6772 - 2.595 0.55 - 799.4 1 2 0 -0.0008 11 0 0 0 1.74E+07 1.23E+07 - - - 5.6827 1 221125_WJC_METTL3_EV_vs_WT_F08.05567.05567.2 3.23E-05 15/20 R.VDSFHESTEGK[136.11].V "sp|Q8WWY3|PRP31_HUMAN,tr|E7EVX8|E7EVX8_HUMAN" 2 1242.5608 1.64 111572 5567 2 1242.559714 622.2877 U4\U6 small nuclear ribonucleoprotein Prp31 OS=Homo sapiens OX=9606 GN=PRPF31 PE=1 SV=2 4.65 1522.8 - 2.13E+06 - - - -0.8708 - 2.875 0.57 - 978 1 2 0 -0.0011 11 0 0 0 2.51E+07 1.53E+07 - - - 6.1076 1 221125_WJC_METTL3_EV_vs_WT_F08.05568.05568.2 1.15E-05 17/22 K.TSGNATVDHLSK.Y sp|Q99496|RING2_HUMAN 1 1228.6048 2.2 111573 5568 2 1228.603171 615.3097 E3 ubiquitin-protein ligase RING2 OS=Homo sapiens OX=9606 GN=RNF2 PE=1 SV=1 6.41 1522.9 - 1.25E+06 - - - -1.3096 - 3.236 0.594 - 1243 1 2 0 -0.0016 12 0 0 0 7.99E+06 3.63E+06 - - - 6.5177 0.9974 221125_WJC_METTL3_EV_vs_WT_F08.05569.05569.3 0.0134 13/36 R.IRNNSAIHIR.V "sp|O75817|POP7_HUMAN,tr|C9JYM0|C9JYM0_HUMAN" 2 1192.6789 1.9 111574 5569 3 1192.674521 398.5669 Ribonuclease P protein subunit p20 OS=Homo sapiens OX=9606 GN=POP7 PE=1 SV=2 12 1523 - 1.01E+06 - - - -3.6615 - 2.416 0.373 - 265.1 1 2 1 -0.0044 10 0 0 0 3.81E+06 2.01E+06 - - - 5.2735 0.8522 221125_WJC_METTL3_EV_vs_WT_F08.05576.05576.2 0.0662 18-Jun V.K[136.11]LNPDFSDAK[136.11].E sp|Q6P2P2|ANM9_HUMAN 1 1149.6001 3 111581 5576 2 1149.601151 575.8073 Protein arginine N-methyltransferase 9 OS=Homo sapiens OX=9606 GN=PRMT9 PE=1 SV=1 5.96 1523.8 - 290108 - - - 0.9247 - 1.436 0.223 - 101.2 1 1 0 0.0011 10 0 0 0 7.88E+06 2.63E+06 - - - 1.6978 0.9998 221125_WJC_METTL3_EV_vs_WT_F08.05577.05577.2 9.76E-05 20-Oct R.IHNQNNEQAWK.E sp|P53701|CCHL_HUMAN 1 1380.6535 -1 111582 5577 2 1380.654824 691.334 Holocytochrome c-type synthase OS=Homo sapiens OX=9606 GN=HCCS PE=1 SV=1 6.75 1523.9 - 390638 - - - 0.9872 - 1.948 0.456 - 364.8 1 2 0 0.0014 11 0 0 0 0.00E+00 0.00E+00 - - - 4.2124 0.9764 221125_WJC_METTL3_EV_vs_WT_F08.05578.05578.2 2.27 22-Jul K.TGK[136.11]PEEASLDSR[166.11].E "sp|Q9BY42|RTF2_HUMAN,tr|A0A0A0MQR2|A0A0A0MQR2_HUMAN,tr|A2A2L5|A2A2L5_HUMAN" 3 1306.6484 -1 111583 5578 2 1306.648534 654.3315 Replication termination factor 2 OS=Homo sapiens OX=9606 GN=RTF2 PE=1 SV=3 4.68 1524.1 - 318633 - - - 0.1186 - 1.079 0.11 - 69 1 2 0 0.0002 12 0 0 0 0.00E+00 0.00E+00 - - - 0.0535 0.9998 221125_WJC_METTL3_EV_vs_WT_F08.05580.05580.2 7.18E-05 13/26 R.VSGQPQSVTASSDK[136.11].A "sp|Q8N6T3|ARFG1_HUMAN,tr|F8VWH9|F8VWH9_HUMAN,tr|E5RHT6|E5RHT6_HUMAN,tr|F8W1U7|F8W1U7_HUMAN,tr|E5RHC5|E5RHC5_HUMAN" 5 1397.6878 1.6 111584 5580 2 1397.687305 699.8512 ADP-ribosylation factor GTPase-activating protein 1 OS=Homo sapiens OX=9606 GN=ARFGAP1 PE=1 SV=2 5.81 1524.4 - 2.13E+06 - - - -0.3449 - 2.111 0.459 - 391.5 1 2 0 -0.0005 14 0 0 0 5.69E+07 3.56E+07 - - - 4.306 0.9999 221125_WJC_METTL3_EV_vs_WT_F08.05583.05583.3 0.00235 Dec-44 K.KGPGLAVQSGDK.T sp|Q96PK6|RBM14_HUMAN 1 1155.6248 1.98 111587 5583 3 1155.623445 386.2155 RNA-binding protein 14 OS=Homo sapiens OX=9606 GN=RBM14 PE=1 SV=2 8.59 1524.6 - 4.64E+06 - - - -1.1613 - 2.674 0.418 - 285.7 1 2 0 -0.0013 12 0 0 0 3.18E+09 1.61E+09 - - - 5.9262 0.9996 221125_WJC_METTL3_EV_vs_WT_F08.05584.05584.2 0.369 16-Oct K.KSLESINSR.L "sp|P62888|RL30_HUMAN,tr|E5RJH3|E5RJH3_HUMAN,tr|E5RI99|E5RI99_HUMAN,tr|A0A0C4DH44|A0A0C4DH44_HUMAN" 4 1032.5564 1.16 111588 5584 2 1032.555392 517.2855 60S ribosomal protein L30 OS=Homo sapiens OX=9606 GN=RPL30 PE=1 SV=2 8.75 1524.6 - 4.34E+06 - - - -0.9501 - 2.15 0.305 - 372.8 1 2 0 -0.001 9 0 0 0 1.43E+07 1.23E+07 - - - 3.508 0.793 221125_WJC_METTL3_EV_vs_WT_F08.05589.05589.2 0.402 18-Jul V.KLNPDFSDAK.E sp|Q6P2P2|ANM9_HUMAN 1 1133.5717 3 111593 5589 2 1133.574566 567.7931 Protein arginine N-methyltransferase 9 OS=Homo sapiens OX=9606 GN=PRMT9 PE=1 SV=1 5.96 1524.9 - 1.33E+06 - - - 2.5389 - 1.58 0.247 - 132.1 1 1 0 0.0029 10 0 0 0 7.88E+06 2.63E+06 - - - 2.1413 0.9934 221125_WJC_METTL3_EV_vs_WT_F08.05590.05590.2 0.00542 16-Oct R.KKNDIYGED.- sp|P50395|GDIB_HUMAN 1 1080.5088 25.31 111594 5590 2 1080.507612 541.2617 Rab GDP dissociation inhibitor beta OS=Homo sapiens OX=9606 GN=GDI2 PE=1 SV=2 4.78 1525 - 1.20E+06 - - - -1.0569 - 1.608 0.358 - 263.7 1 2 1 -0.0011 9 0 0 0 9.14E+07 3.61E+06 - - - 3.059 1 221125_WJC_METTL3_EV_vs_WT_F08.05591.05591.2 2.26E-07 19/22 K.KGPGLAVQSGDK.T sp|Q96PK6|RBM14_HUMAN 1 1155.6248 1.99 111595 5591 2 1155.621823 578.8197 RNA-binding protein 14 OS=Homo sapiens OX=9606 GN=RBM14 PE=1 SV=2 8.59 1525.1 - 969525 - - - -2.5648 - 3.246 0.543 - 1065.2 1 2 0 -0.003 12 0 0 0 9.34E+08 4.69E+08 - - - 6.1487 0.9969 221125_WJC_METTL3_EV_vs_WT_F08.05594.05594.2 0.0064 16-Sep R.K[136.11]K[136.11]NDIYGED.- sp|P50395|GDIB_HUMAN 1 1096.5372 26.56 111598 5594 2 1096.536131 549.2759 Rab GDP dissociation inhibitor beta OS=Homo sapiens OX=9606 GN=GDI2 PE=1 SV=2 4.78 1525.4 - 759975 - - - -0.9329 - 1.729 0.439 - 256 1 2 1 -0.001 9 0 0 0 8.61E+07 3.24E+06 - - - 3.8672 0.9999 221125_WJC_METTL3_EV_vs_WT_F08.05596.05596.2 0.00184 20-Dec K.SQEAQSLQQQR[166.11].D "sp|Q08379|GOGA2_HUMAN,tr|A0A6Q8KRG2|A0A6Q8KRG2_HUMAN,tr|A0A1W2PQY5|A0A1W2PQY5_HUMAN" 3 1311.6407 -1 111600 5596 2 1311.639687 656.8276 Golgin subfamily A member 2 OS=Homo sapiens OX=9606 GN=GOLGA2 PE=1 SV=3 5.72 1525.7 - 353790 - - - -0.7426 - 2.499 0.464 - 718.9 1 2 0 -0.001 11 0 0 0 0.00E+00 0.00E+00 - - - 4.9455 1 221125_WJC_METTL3_EV_vs_WT_F08.05601.05601.3 4.94E-06 Dec-44 K.K[136.11]GPGLAVQSGDK[136.11].T sp|Q96PK6|RBM14_HUMAN 1 1171.6532 1.98 111603 5601 3 1171.65202 391.5583 RNA-binding protein 14 OS=Homo sapiens OX=9606 GN=RBM14 PE=1 SV=2 8.59 1526.4 - 7.86E+07 - - - -0.996 - 2.662 0.561 - 307.5 1 2 0 -0.0012 12 0 0 0 3.18E+09 1.61E+09 - - - 7.5081 1 221125_WJC_METTL3_EV_vs_WT_F08.05602.05602.2 1.20E-07 16/22 K.K[136.11]GPGLAVQSGDK[136.11].T sp|Q96PK6|RBM14_HUMAN 1 1171.6532 1.99 111604 5602 2 1171.652538 586.8339 RNA-binding protein 14 OS=Homo sapiens OX=9606 GN=RBM14 PE=1 SV=2 8.59 1526.4 - 1.76E+07 - - - -0.5539 - 3.018 0.585 - 774.5 1 2 0 -0.0006 12 0 0 0 9.34E+08 4.69E+08 - - - 6.268 1 221125_WJC_METTL3_EV_vs_WT_F08.05603.05603.3 4.92E-05 18/48 R.VEAKPEVQSQPPR.V "sp|Q9UN86|G3BP2_HUMAN,tr|A0A7I2V3E2|A0A7I2V3E2_HUMAN,tr|A0A7I2V647|A0A7I2V647_HUMAN,tr|A0A7I2V3Z6|A0A7I2V3Z6_HUMAN,tr|A0A7I2YQD9|A0A7I2YQD9_HUMAN,tr|A0A7I2V382|A0A7I2V382_HUMAN,tr|A0A7I2V547|A0A7I2V547_HUMAN,tr|A0A7I2V3P9|A0A7I2V3P9_HUMAN" 8 1463.7732 1.64 111605 5603 3 1463.772711 488.9317 Ras GTPase-activating protein-binding protein 2 OS=Homo sapiens OX=9606 GN=G3BP2 PE=1 SV=2 6.11 1526.4 - 1.58E+07 - - - -0.3628 - 2.894 0.441 - 507.9 1 2 0 -0.0005 13 0 0 0 1.71E+09 1.05E+09 - - - 6.3377 1 221125_WJC_METTL3_EV_vs_WT_F08.05604.05604.3 2.91E-06 17/48 R.VEAK[136.11]PEVQSQPPR[166.11].V "sp|Q9UN86|G3BP2_HUMAN,tr|A0A7I2V3E2|A0A7I2V3E2_HUMAN,tr|A0A7I2V647|A0A7I2V647_HUMAN,tr|A0A7I2V3Z6|A0A7I2V3Z6_HUMAN,tr|A0A7I2YQD9|A0A7I2YQD9_HUMAN,tr|A0A7I2V382|A0A7I2V382_HUMAN,tr|A0A7I2V547|A0A7I2V547_HUMAN,tr|A0A7I2V3P9|A0A7I2V3P9_HUMAN" 8 1481.7957 1.64 111606 5604 3 1481.794601 494.9392 Ras GTPase-activating protein-binding protein 2 OS=Homo sapiens OX=9606 GN=G3BP2 PE=1 SV=2 6.11 1526.5 - 1.33E+07 - - - -0.7498 - 2.729 0.529 - 435.7 1 2 0 -0.0011 13 0 0 0 1.71E+09 1.05E+09 - - - 7.1595 0.9988 221125_WJC_METTL3_EV_vs_WT_F08.05605.05605.3 0.0878 Oct-36 R.TAQEVETYR[166.11]R[166.11].S "sp|P17844|DDX5_HUMAN,tr|J3QR02|J3QR02_HUMAN,tr|A0A7I2V507|A0A7I2V507_HUMAN,tr|J3KTA4|J3KTA4_HUMAN,tr|J3KTQ4|J3KTQ4_HUMAN,tr|A0A7I2V2S0|A0A7I2V2S0_HUMAN,tr|J3QRQ7|J3QRQ7_HUMAN" 7 1271.6373 1.59 111607 5605 3 1271.636232 424.8864 Probable ATP-dependent RNA helicase DDX5 OS=Homo sapiens OX=9606 GN=DDX5 PE=1 SV=1 5.81 1526.5 - 1.26E+07 - - - -0.843 - 2.221 0.209 - 181.5 1 2 0 -0.0011 10 0 0 0 7.05E+07 4.44E+07 - - - 3.2002 0.9999 221125_WJC_METTL3_EV_vs_WT_F08.05608.05608.2 0.000433 16-Dec R.QDEHGYISR.C "sp|P04792|HSPB1_HUMAN,tr|A0A6Q8PHJ6|A0A6Q8PHJ6_HUMAN,tr|A0A6Q8PFK8|A0A6Q8PFK8_HUMAN,tr|A0A6Q8PGK1|A0A6Q8PGK1_HUMAN" 4 1103.4996 2.12 111610 5608 2 1103.498746 552.7571 Heat shock protein beta-1 OS=Homo sapiens OX=9606 GN=HSPB1 PE=1 SV=2 5.32 1526.7 - 2.41E+06 - - - -0.7612 - 2.114 0.485 - 594.2 1 2 0 -0.0008 9 0 0 0 9.00E+07 4.24E+07 - - - 4.7886 0.9998 221125_WJC_METTL3_EV_vs_WT_F08.05609.05609.2 0.00104 16-Nov R.QDEHGYISR[166.11].C "sp|P04792|HSPB1_HUMAN,tr|A0A6Q8PHJ6|A0A6Q8PHJ6_HUMAN,tr|A0A6Q8PFK8|A0A6Q8PFK8_HUMAN,tr|A0A6Q8PGK1|A0A6Q8PGK1_HUMAN" 4 1113.5079 2.12 111611 5609 2 1113.505973 557.7612 Heat shock protein beta-1 OS=Homo sapiens OX=9606 GN=HSPB1 PE=1 SV=2 5.32 1526.8 - 1.67E+06 - - - -1.6911 - 2.038 0.488 - 541.3 1 2 0 -0.0019 9 0 0 0 9.00E+07 4.24E+07 - - - 4.7045 0.998 221125_WJC_METTL3_EV_vs_WT_F08.05611.05611.2 0.00174 20-Dec K.IKQELGEESTR.L sp|Q5JSZ5|PRC2B_HUMAN 1 1288.6623 1.21 111613 5611 2 1288.663718 645.3384 Protein PRRC2B OS=Homo sapiens OX=9606 GN=PRRC2B PE=1 SV=2 4.79 1527 - 1.27E+06 - - - 1.105 - 2.366 0.462 - 401.7 1 2 1 0.0014 11 0 0 0 7.54E+06 6.25E+06 - - - 4.7826 0.9997 221125_WJC_METTL3_EV_vs_WT_F08.05612.05612.2 0.00196 18-Nov R.TAQEVETYRR.S "sp|P17844|DDX5_HUMAN,tr|J3QR02|J3QR02_HUMAN,tr|A0A7I2V507|A0A7I2V507_HUMAN,tr|J3KTA4|J3KTA4_HUMAN,tr|J3KTQ4|J3KTQ4_HUMAN,tr|A0A7I2V2S0|A0A7I2V2S0_HUMAN,tr|J3QRQ7|J3QRQ7_HUMAN" 7 1251.6208 0.87 111614 5612 2 1251.621493 626.8177 Probable ATP-dependent RNA helicase DDX5 OS=Homo sapiens OX=9606 GN=DDX5 PE=1 SV=1 5.81 1527.1 - 1.17E+06 - - - 0.5824 - 1.826 0.393 - 225.7 1 2 0 0.0007 10 0 0 0 5.40E+06 6.19E+06 - - - 3.6242 0.998 221125_WJC_METTL3_EV_vs_WT_F08.05614.05614.2 2.78E-05 20-Oct K.IK[136.11]QELGEESTR[166.11].L sp|Q5JSZ5|PRC2B_HUMAN 1 1306.6848 1.21 111616 5614 2 1306.683319 654.3497 Protein PRRC2B OS=Homo sapiens OX=9606 GN=PRRC2B PE=1 SV=2 4.79 1527.4 - 1.13E+06 - - - -1.1059 - 2.05 0.487 - 221.1 1 2 1 -0.0014 11 0 0 0 7.54E+06 6.25E+06 - - - 4.5795 0.9998 221125_WJC_METTL3_EV_vs_WT_F08.05616.05616.2 1.61E-05 21/32 R.GPTPGQAPAGGAGAEGK.G "sp|Q96NU1|SAM11_HUMAN,tr|A0A087WYW1|A0A087WYW1_HUMAN,tr|A0A087WX24|A0A087WX24_HUMAN,tr|A0A087X1J5|A0A087X1J5_HUMAN,tr|A0A087X223|A0A087X223_HUMAN,tr|H7BY14|H7BY14_HUMAN,tr|A0A087WXB3|A0A087WXB3_HUMAN,tr|H7C3J6|H7C3J6_HUMAN,tr|A0A087WYU3|A0A087WYU3_HUMAN,tr|A0A087WU74|A0A087WU74_HUMAN" 10 1421.6899 1.69 111618 5616 2 1421.687392 711.8522 Sterile alpha motif domain-containing protein 11 OS=Homo sapiens OX=9606 GN=SAMD11 PE=1 SV=3 6 1527.6 - 974861 - - - -1.7683 - 2.501 0.543 - 608.4 1 2 0 -0.0025 17 0 0 0 3.53E+07 2.09E+07 - - - 5.3045 1 221125_WJC_METTL3_EV_vs_WT_F08.05619.05619.2 6.73E-07 18/24 R.VEAKPEVQSQPPR.V "sp|Q9UN86|G3BP2_HUMAN,tr|A0A7I2V3E2|A0A7I2V3E2_HUMAN,tr|A0A7I2V647|A0A7I2V647_HUMAN,tr|A0A7I2V3Z6|A0A7I2V3Z6_HUMAN,tr|A0A7I2YQD9|A0A7I2YQD9_HUMAN,tr|A0A7I2V382|A0A7I2V382_HUMAN,tr|A0A7I2V547|A0A7I2V547_HUMAN,tr|A0A7I2V3P9|A0A7I2V3P9_HUMAN" 8 1463.7732 1.71 111621 5619 2 1463.769985 732.8939 Ras GTPase-activating protein-binding protein 2 OS=Homo sapiens OX=9606 GN=G3BP2 PE=1 SV=2 6.11 1528 - 403840 - - - -2.2251 - 2.831 0.576 - 711.4 1 2 0 -0.0033 13 0 0 0 8.32E+07 4.86E+07 - - - 5.9651 0.9998 221125_WJC_METTL3_EV_vs_WT_F08.05624.05624.3 9.78E-05 Nov-44 K.KGPGLAVQSGDK[136.11].T sp|Q96PK6|RBM14_HUMAN 1 1163.639 - 111624 5624 3 1163.636155 388.8869 RNA-binding protein 14 OS=Homo sapiens OX=9606 GN=RBM14 PE=1 SV=2 8.59 1528.5 - 4.97E+06 - - - -2.4337 - 2.142 0.414 - 211.3 1 2 0 -0.0028 12 0 0 0 - - - - - 5.2663 0.9999 221125_WJC_METTL3_EV_vs_WT_F08.05625.05625.3 0.000457 13/52 K.SGAEVEAGDAAERR.A "sp|Q8IY67|RAVR1_HUMAN,tr|K7EKR9|K7EKR9_HUMAN,tr|E9PAU2|E9PAU2_HUMAN,tr|A0A087WZ13|A0A087WZ13_HUMAN" 4 1416.6593 2.1 111625 5625 3 1416.656567 473.2271 Ribonucleoprotein PTB-binding 1 OS=Homo sapiens OX=9606 GN=RAVER1 PE=1 SV=1 4.41 1528.6 - 5.56E+06 - - - -1.9532 - 2.688 0.38 - 354.7 1 2 0 -0.0028 14 0 0 0 4.37E+07 2.08E+07 - - - 5.4036 0.9999 221125_WJC_METTL3_EV_vs_WT_F08.05626.05626.2 1.08E-06 15/24 R.VEAK[136.11]PEVQSQPPR[166.11].V "sp|Q9UN86|G3BP2_HUMAN,tr|A0A7I2V3E2|A0A7I2V3E2_HUMAN,tr|A0A7I2V647|A0A7I2V647_HUMAN,tr|A0A7I2V3Z6|A0A7I2V3Z6_HUMAN,tr|A0A7I2YQD9|A0A7I2YQD9_HUMAN,tr|A0A7I2V382|A0A7I2V382_HUMAN,tr|A0A7I2V547|A0A7I2V547_HUMAN,tr|A0A7I2V3P9|A0A7I2V3P9_HUMAN" 8 1481.7957 1.71 111626 5626 2 1481.793979 741.9051 Ras GTPase-activating protein-binding protein 2 OS=Homo sapiens OX=9606 GN=G3BP2 PE=1 SV=2 6.11 1528.6 - 4.33E+06 - - - -1.1695 - 2.44 0.588 - 499.5 1 2 0 -0.0017 13 0 0 0 8.32E+07 4.86E+07 - - - 5.6728 1 221125_WJC_METTL3_EV_vs_WT_F08.05632.05632.2 2.64E-08 19/32 R.GPTPGQAPAGGAGAEGK[136.11].G "sp|Q96NU1|SAM11_HUMAN,tr|A0A087WYW1|A0A087WYW1_HUMAN,tr|A0A087WX24|A0A087WX24_HUMAN,tr|A0A087X1J5|A0A087X1J5_HUMAN,tr|A0A087X223|A0A087X223_HUMAN,tr|H7BY14|H7BY14_HUMAN,tr|A0A087WXB3|A0A087WXB3_HUMAN,tr|H7C3J6|H7C3J6_HUMAN,tr|A0A087WYU3|A0A087WYU3_HUMAN,tr|A0A087WU74|A0A087WU74_HUMAN" 10 1429.7041 1.69 111632 5632 2 1429.703655 715.8593 Sterile alpha motif domain-containing protein 11 OS=Homo sapiens OX=9606 GN=SAMD11 PE=1 SV=3 6 1529 - 1.87E+06 - - - -0.3154 - 2.981 0.606 - 881.2 1 2 0 -0.0005 17 0 0 0 3.53E+07 2.09E+07 - - - 6.2021 0.9901 221125_WJC_METTL3_EV_vs_WT_F08.05633.05633.2 9.91E-07 15/22 V.EAKPEVQSQPPR.V "sp|Q9UN86|G3BP2_HUMAN,tr|A0A7I2V3E2|A0A7I2V3E2_HUMAN,tr|A0A7I2V647|A0A7I2V647_HUMAN,tr|A0A7I2V3Z6|A0A7I2V3Z6_HUMAN,tr|A0A7I2YQD9|A0A7I2YQD9_HUMAN,tr|A0A7I2V382|A0A7I2V382_HUMAN,tr|A0A7I2V547|A0A7I2V547_HUMAN,tr|A0A7I2V3P9|A0A7I2V3P9_HUMAN" 8 1364.7048 1.92 111633 5633 2 1364.702773 683.3597 Ras GTPase-activating protein-binding protein 2 OS=Homo sapiens OX=9606 GN=G3BP2 PE=1 SV=2 6.24 1529.2 - 1.61E+06 - - - -1.5058 - 2.44 0.501 - 398.4 1 1 0 -0.0021 12 0 0 0 1.97E+07 1.03E+07 - - - 5.0877 0.9984 221125_WJC_METTL3_EV_vs_WT_F08.05634.05634.2 11.4 18-Dec R.NADSGVHLNR[166.11].L "sp|Q6PJT7|ZC3HE_HUMAN,tr|G3V3Y4|G3V3Y4_HUMAN,tr|G3V256|G3V256_HUMAN,tr|G3V5I6|G3V5I6_HUMAN,tr|A0A3B3IT62|A0A3B3IT62_HUMAN,tr|H0YJA2|H0YJA2_HUMAN" 6 1091.5347 1.49 111634 5634 2 1091.530431 546.7746 Zinc finger CCCH domain-containing protein 14 OS=Homo sapiens OX=9606 GN=ZC3H14 PE=1 SV=1 6.74 1529.3 - 1.43E+06 - - - -3.9477 - 2.408 0.378 - 695 1 2 0 -0.0043 10 0 0 0 1.46E+07 9.82E+06 - - - 4.2845 0.9999 221125_WJC_METTL3_EV_vs_WT_F08.05635.05635.2 8.23E-06 16/22 K.KGPGLAVQSGDK[136.11].T sp|Q96PK6|RBM14_HUMAN 1 1163.639 - 111635 5635 2 1163.63854 582.8268 RNA-binding protein 14 OS=Homo sapiens OX=9606 GN=RBM14 PE=1 SV=2 8.59 1529.4 - 1.20E+06 - - - -0.3841 - 2.649 0.448 - 660.6 1 2 0 -0.0004 12 0 0 0 - - - - - 4.913 1 221125_WJC_METTL3_EV_vs_WT_F08.05640.05640.3 1.89E-09 21/56 R.PASVSSSAAVEHEQR.E sp|Q7Z5L9|I2BP2_HUMAN 1 1553.7434 1.55 111638 5640 3 1553.742633 518.9217 Interferon regulatory factor 2-binding protein 2 OS=Homo sapiens OX=9606 GN=IRF2BP2 PE=1 SV=2 5.41 1530 - 6.95E+06 - - - -0.4924 - 3.651 0.631 - 612.6 1 1 0 -0.0008 15 0 0 0 8.57E+07 5.51E+07 - - - 8.9539 0.9993 221125_WJC_METTL3_EV_vs_WT_F08.05642.05642.3 0.00192 Nov-48 R.K[136.11]TGPAAAQVQVGK[136.11].Q "sp|Q13428|TCOF_HUMAN,tr|E7ETY2|E7ETY2_HUMAN,tr|H0Y8Y7|H0Y8Y7_HUMAN,tr|A0A3B3IS06|A0A3B3IS06_HUMAN,tr|A0A6I8PRA0|A0A6I8PRA0_HUMAN" 5 1269.7376 1.32 111640 5642 3 1269.739695 424.2531 Treacle protein OS=Homo sapiens OX=9606 GN=TCOF1 PE=1 SV=3 10 1530.2 - 2.55E+06 - - - 1.6618 - 2.082 0.305 - 216.4 1 2 0 0.0021 13 0 0 0 2.35E+07 1.78E+07 - - - 3.9281 0.9709 221125_WJC_METTL3_EV_vs_WT_F08.05645.05645.2 4.07E-05 20-Oct E.AK[136.11]PEVQSQPPR[166.11].V "sp|Q9UN86|G3BP2_HUMAN,tr|A0A7I2V3E2|A0A7I2V3E2_HUMAN,tr|A0A7I2V647|A0A7I2V647_HUMAN,tr|A0A7I2V3Z6|A0A7I2V3Z6_HUMAN,tr|A0A7I2YQD9|A0A7I2YQD9_HUMAN,tr|A0A7I2V382|A0A7I2V382_HUMAN,tr|A0A7I2V547|A0A7I2V547_HUMAN,tr|A0A7I2V3P9|A0A7I2V3P9_HUMAN" 8 1253.6847 3.18 111643 5645 2 1253.686757 627.8496 Ras GTPase-activating protein-binding protein 2 OS=Homo sapiens OX=9606 GN=G3BP2 PE=1 SV=2 8.79 1530.5 - 883390 - - - 1.6368 - 1.793 0.418 - 295.6 1 1 0 0.0021 11 0 0 0 1.44E+07 4.53E+06 - - - 3.7073 1 221125_WJC_METTL3_EV_vs_WT_F08.05649.05649.2 4.67E-05 14/24 K.TC[160.03]VADESAENC[160.03]DK.S "sp|P02768|ALBU_HUMAN,tr|A0A087WWT3|A0A087WWT3_HUMAN,tr|H7C013|H7C013_HUMAN,tr|A0A0C4DGB6|A0A0C4DGB6_HUMAN" 4 1497.5712 999 111645 5649 2 1497.570679 749.7929 Albumin OS=Homo sapiens OX=9606 GN=ALB PE=1 SV=2 3.92 1531 - 4.15E+06 - - - -0.3299 - 2.644 0.668 - 642.2 1 2 0 -0.0005 13 0 0 0 5.00E+07 0.00E+00 - - - 6.4701 0.9999 221125_WJC_METTL3_EV_vs_WT_F08.05653.05653.3 0.00278 13/48 R.KTGPAAAQVQVGK.Q "sp|Q13428|TCOF_HUMAN,tr|E7ETY2|E7ETY2_HUMAN,tr|H0Y8Y7|H0Y8Y7_HUMAN,tr|A0A3B3IS06|A0A3B3IS06_HUMAN,tr|A0A6I8PRA0|A0A6I8PRA0_HUMAN" 5 1253.7092 1.31 111649 5653 3 1253.707524 418.9103 Treacle protein OS=Homo sapiens OX=9606 GN=TCOF1 PE=1 SV=3 10 1531.2 - 3.17E+06 - - - -1.3249 - 2.644 0.341 - 323.1 1 2 0 -0.0017 13 0 0 0 2.36E+07 1.81E+07 - - - 4.9775 1 221125_WJC_METTL3_EV_vs_WT_F08.05654.05654.3 2.49E-07 14/56 R.ITAAQHSVTGSAVSK.T "sp|Q13492|PICAL_HUMAN,tr|E9PK13|E9PK13_HUMAN,tr|E9PJT1|E9PJT1_HUMAN" 3 1455.7682 0.05 111650 5654 3 1455.768352 486.2633 Phosphatidylinositol-binding clathrin assembly protein OS=Homo sapiens OX=9606 GN=PICALM PE=1 SV=2 8.76 1531.2 - 2.77E+06 - - - 0.1339 - 3.182 0.512 - 267.1 1 2 0 0.0002 15 0 0 0 8.24E+07 1.70E+09 - - - 7.2686 0.9999 221125_WJC_METTL3_EV_vs_WT_F08.05655.05655.3 0.0198 14/48 R.VEAKPEVQSQPPR[166.11].V "sp|Q9UN86|G3BP2_HUMAN,tr|A0A7I2V3E2|A0A7I2V3E2_HUMAN,tr|A0A7I2V647|A0A7I2V647_HUMAN,tr|A0A7I2V3Z6|A0A7I2V3Z6_HUMAN,tr|A0A7I2YQD9|A0A7I2YQD9_HUMAN,tr|A0A7I2V382|A0A7I2V382_HUMAN,tr|A0A7I2V547|A0A7I2V547_HUMAN,tr|A0A7I2V3P9|A0A7I2V3P9_HUMAN" 8 1473.7815 - 111651 5655 3 1473.780004 492.2678 Ras GTPase-activating protein-binding protein 2 OS=Homo sapiens OX=9606 GN=G3BP2 PE=1 SV=2 6.11 1531.3 - 2.00E+06 - - - -1.0232 - 2.726 0.347 - 268.6 1 2 0 -0.0015 13 0 0 0 - - - - - 5.1273 0.9997 221125_WJC_METTL3_EV_vs_WT_F08.05656.05656.3 9.24E-07 Nov-40 R.KITIGQGNTEK.G "sp|Q6UB35|C1TM_HUMAN,tr|A0A087WVM4|A0A087WVM4_HUMAN,tr|B7ZM99|B7ZM99_HUMAN" 3 1187.651 0.67 111652 5656 3 1187.647931 396.8909 "Monofunctional C1-tetrahydrofolate synthase, mitochondrial OS=Homo sapiens OX=9606 GN=MTHFD1L PE=1 SV=1" 8.59 1531.4 - 1.74E+06 - - - -2.5849 - 2.474 0.364 - 163 1 2 0 -0.0031 11 0 0 0 1.46E+07 2.19E+07 - - - 5.1707 0.9995 221125_WJC_METTL3_EV_vs_WT_F08.05657.05657.2 2.25E-06 22-Dec R.DSAQTSVTQAQR.E "sp|Q14980|NUMA1_HUMAN,tr|A0A087WY61|A0A087WY61_HUMAN,tr|F5H4J1|F5H4J1_HUMAN,tr|F5H6Y5|F5H6Y5_HUMAN" 4 1290.6164 0.73 111653 5657 2 1290.620344 646.3155 Nuclear mitotic apparatus protein 1 OS=Homo sapiens OX=9606 GN=NUMA1 PE=1 SV=2 5.84 1531.5 - 821196 - - - 3.0505 - 2.363 0.519 - 564.4 1 2 0 0.0039 12 0 0 0 7.26E+06 9.96E+06 - - - 5.1357 1 221125_WJC_METTL3_EV_vs_WT_F08.05662.05662.3 1.33E-09 23/56 R.PASVSSSAAVEHEQR[166.11].E sp|Q7Z5L9|I2BP2_HUMAN 1 1563.7517 1.55 111656 5662 3 1563.750326 522.2578 Interferon regulatory factor 2-binding protein 2 OS=Homo sapiens OX=9606 GN=IRF2BP2 PE=1 SV=2 5.41 1532.1 - 6.28E+06 - - - -0.8582 - 3.933 0.647 - 980.6 1 1 0 -0.0013 15 0 0 0 8.57E+07 5.51E+07 - - - 9.3263 0.955 221125_WJC_METTL3_EV_vs_WT_F08.05663.05663.3 0.0455 Dec-44 P.VSTR[166.11]PLPSASQK[136.11].A sp|Q8ND56|LS14A_HUMAN 1 1287.7266 1.21 111657 5663 3 1287.726313 430.2495 Protein LSM14 homolog A OS=Homo sapiens OX=9606 GN=LSM14A PE=1 SV=3 11 1532.1 - 2.99E+06 - - - -0.1996 - 2.341 0.27 - 165 1 1 0 -0.0003 12 0 0 0 5.06E+07 4.18E+07 - - - 3.9078 0.9993 221125_WJC_METTL3_EV_vs_WT_F08.05665.05665.3 0.00759 Jul-40 K.SNHEQEVNTLR.C sp|Q15323|K1H1_HUMAN 1 1325.6324 1.34 111659 5665 3 1325.632816 442.8847 "Keratin, type I cuticular Ha1 OS=Homo sapiens OX=9606 GN=KRT31 PE=1 SV=3" 5.38 1532.2 - 2.33E+06 - - - 0.3206 - 1.652 0.326 - 94.2 1 2 0 0.0004 11 0 0 0 1.86E+07 1.38E+07 - - - 3.6005 1 221125_WJC_METTL3_EV_vs_WT_F08.05670.05670.2 1.19E-07 13/22 R.DSAQTSVTQAQR[166.11].E "sp|Q14980|NUMA1_HUMAN,tr|A0A087WY61|A0A087WY61_HUMAN,tr|F5H4J1|F5H4J1_HUMAN,tr|F5H6Y5|F5H6Y5_HUMAN" 4 1300.6247 0.69 111664 5670 2 1300.62681 651.3196 Nuclear mitotic apparatus protein 1 OS=Homo sapiens OX=9606 GN=NUMA1 PE=1 SV=2 5.84 1532.6 - 870642 - - - 1.64 - 2.803 0.58 - 765.7 1 2 0 0.0021 12 0 0 0 7.26E+06 1.05E+07 - - - 6.0361 0.9989 221125_WJC_METTL3_EV_vs_WT_F08.05674.05674.3 0.029 Nov-32 R.GR[166.11]PHVYLQR[166.11].L sp|Q8IYS2|K2013_HUMAN 1 1144.6369 0.001 111666 5674 3 1144.63811 382.5529 Uncharacterized protein KIAA2013 OS=Homo sapiens OX=9606 GN=KIAA2013 PE=1 SV=1 10.84 1533.2 - 3.02E+06 - - - 1.1008 - 2.009 0.245 - 264.5 1 2 0 0.0013 9 0 0 0 0.00E+00 3.15E+07 - - - 3.3737 0.9892 221125_WJC_METTL3_EV_vs_WT_F08.05675.05675.3 0.152 Aug-44 R.NPPPNSDPNLRR.F sp|Q96I24|FUBP3_HUMAN 1 1375.6957 1.31 111667 5675 3 1375.693856 459.5725 Far upstream element-binding protein 3 OS=Homo sapiens OX=9606 GN=FUBP3 PE=1 SV=2 9.6 1533.2 - 2.70E+06 - - - -1.3113 - 1.424 0.209 - 60 1 2 0 -0.0018 12 0 0 0 7.40E+07 5.64E+07 - - - 1.8494 0.9881 221125_WJC_METTL3_EV_vs_WT_F08.05676.05676.3 0.206 Jul-44 R.NPPPNSDPNLRR.F sp|Q96I24|FUBP3_HUMAN 1 1375.6957 1.31 111668 5676 3 1375.693649 459.5725 Far upstream element-binding protein 3 OS=Homo sapiens OX=9606 GN=FUBP3 PE=1 SV=2 9.6 1533.3 - 2.70E+06 - - - -1.4618 - 1.265 0.238 - 49.9 1 2 0 -0.002 12 0 0 0 7.40E+07 5.64E+07 - - - 1.8445 0.9904 221125_WJC_METTL3_EV_vs_WT_F08.05678.05678.3 0.0391 Jul-36 K.EQGSWGREER.G sp|P47929|LEG7_HUMAN 1 1232.5534 0.63 111670 5678 3 1232.552436 411.8584 Galectin-7 OS=Homo sapiens OX=9606 GN=LGALS7 PE=1 SV=2 4.79 1533.4 - 1.73E+06 - - - -0.7927 - 1.668 0.248 - 105 1 2 1 -0.001 10 0 0 0 1.02E+07 1.62E+07 - - - 2.7989 1 221125_WJC_METTL3_EV_vs_WT_F08.05679.05679.2 4.98E-14 20/28 R.ITAAQHSVTGSAVSK.T "sp|Q13492|PICAL_HUMAN,tr|E9PK13|E9PK13_HUMAN,tr|E9PJT1|E9PJT1_HUMAN" 3 1455.7682 0.43 111671 5679 2 1455.767474 728.8914 Phosphatidylinositol-binding clathrin assembly protein OS=Homo sapiens OX=9606 GN=PICALM PE=1 SV=2 8.76 1533.5 - 1.10E+06 - - - -0.4692 - 3.633 0.692 - 1295.8 1 2 0 -0.0007 15 0 0 0 6.36E+06 1.50E+07 - - - 7.3236 0.909 221125_WJC_METTL3_EV_vs_WT_F08.05682.05682.2 0.0007 20-Aug R.NPQQHLNAQPQ.V "sp|P11940|PABP1_HUMAN,tr|H0YAS6|H0YAS6_HUMAN,tr|H0YB75|H0YB75_HUMAN,tr|H0YAS7|H0YAS7_HUMAN,tr|A0A7I2YQE4|A0A7I2YQE4_HUMAN,tr|H0YAW6|H0YAW6_HUMAN,tr|A0A7I2V649|A0A7I2V649_HUMAN,tr|H0YAR2|H0YAR2_HUMAN,tr|E7ERJ7|E7ERJ7_HUMAN,tr|A0A7I2YQ88|A0A7I2YQ88_HUMAN,tr|A0A087WTT1|A0A087WTT1_HUMAN,tr|A0A7I2YQ90|A0A7I2YQ90_HUMAN,tr|A0A7I2V4N4|A0A7I2V4N4_HUMAN,tr|E7EQV3|E7EQV3_HUMAN" 14 1273.6163 - 111674 5682 2 1273.612069 637.8154 Polyadenylate-binding protein 1 OS=Homo sapiens OX=9606 GN=PABPC1 PE=1 SV=2 6.74 1533.9 - 717925 - - - -3.3589 - 1.884 0.39 - 144 1 1 0 -0.0043 11 0 0 0 - - - - - 3.6337 0.9999 221125_WJC_METTL3_EV_vs_WT_F08.05688.05688.2 1.22E-06 13/28 R.SVQAGNPGGPGPGGR[166.11].G "sp|Q96AE4|FUBP1_HUMAN,tr|E9PEB5|E9PEB5_HUMAN" 2 1316.6461 -1 111680 5688 2 1316.64611 659.3303 Far upstream element-binding protein 1 OS=Homo sapiens OX=9606 GN=FUBP1 PE=1 SV=3 9.47 1534.7 - 204974 - - - 0.022 - 2.788 0.454 - 398.5 1 2 0 0 15 0 0 0 0.00E+00 0.00E+00 - - - 4.915 0.995 221125_WJC_METTL3_EV_vs_WT_F08.05691.05691.2 0.267 18-Oct K.VQVSYK[136.11]GETK[136.11].A "sp|P0DMV8|HS71A_HUMAN,sp|P0DMV9|HS71B_HUMAN,tr|A0A0G2JIW1|A0A0G2JIW1_HUMAN" 3 1153.6314 0.12 111681 5691 2 1153.630262 577.823 Heat shock 70 kDa protein 1A OS=Homo sapiens OX=9606 GN=HSPA1A PE=1 SV=1 8.47 1535.1 - 7.06E+07 - - - -0.9769 - 1.972 0.322 - 435.6 1 2 1 -0.0011 10 0 0 0 9.25E+07 7.64E+08 - - - 3.3144 0.854 221125_WJC_METTL3_EV_vs_WT_F08.05693.05693.2 1.87E-05 16-Dec V.QVSYK[136.11]GETK[136.11].A "sp|P0DMV8|HS71A_HUMAN,sp|P0DMV9|HS71B_HUMAN,tr|A0A0G2JIW1|A0A0G2JIW1_HUMAN" 3 1054.563 0.31 111683 5693 2 1054.562001 528.2888 Heat shock 70 kDa protein 1A OS=Homo sapiens OX=9606 GN=HSPA1A PE=1 SV=1 8.5 1535.1 - 1.76E+07 - - - -0.9236 - 2.148 0.367 - 608.6 1 1 1 -0.001 9 0 0 0 5.87E+07 1.90E+08 - - - 3.9632 0.9929 221125_WJC_METTL3_EV_vs_WT_F08.05696.05696.3 0.0084 Oct-36 K.VQVSYKGETK[136.11].A "sp|P0DMV8|HS71A_HUMAN,sp|P0DMV9|HS71B_HUMAN,tr|A0A0G2JIW1|A0A0G2JIW1_HUMAN" 3 1145.6172 - 111686 5696 3 1145.616032 382.8797 Heat shock 70 kDa protein 1A OS=Homo sapiens OX=9606 GN=HSPA1A PE=1 SV=1 8.47 1535.2 - 8.87E+06 - - - -1.0099 - 2.193 0.195 - 207.7 1 2 1 -0.0012 10 0 0 0 - - - - - 3.0071 0.9955 221125_WJC_METTL3_EV_vs_WT_F08.05698.05698.3 0.038 Oct-36 K.QVEDEKNSFR.E sp|P35579|MYH9_HUMAN 1 1250.5891 0.72 111688 5698 3 1250.587726 417.8703 Myosin-9 OS=Homo sapiens OX=9606 GN=MYH9 PE=1 SV=4 4.68 1535.3 - 5.13E+06 - - - -1.1219 - 1.62 0.306 - 178 1 2 1 -0.0014 10 0 0 0 2.14E+07 2.95E+07 - - - 3.3601 0.9996 221125_WJC_METTL3_EV_vs_WT_F08.05700.05700.2 1.44E-07 22-Oct K.SSSQTSGSLVSK[136.11].S sp|Q9NXV6|CARF_HUMAN 1 1174.5921 0.73 111690 5700 2 1174.591123 588.3033 CDKN2A-interacting protein OS=Homo sapiens OX=9606 GN=CDKN2AIP PE=1 SV=3 8.47 1535.4 - 2.94E+06 - - - -0.8284 - 2.252 0.318 - 453.3 1 2 0 -0.001 12 0 0 0 1.15E+07 1.57E+07 - - - 3.5255 0.9996 221125_WJC_METTL3_EV_vs_WT_F08.05701.05701.3 0.0022 Sep-40 K.DGIDHSNIGNK[136.11].M sp|P52756|RBM5_HUMAN 1 1176.5615 3.44 111691 5701 3 1176.560986 393.1944 RNA-binding protein 5 OS=Homo sapiens OX=9606 GN=RBM5 PE=1 SV=2 5.21 1535.5 - 2.91E+06 - - - -0.4071 - 1.585 0.366 - 78.6 1 2 0 -0.0005 11 0 0 0 4.79E+07 1.40E+07 - - - 3.9288 1 221125_WJC_METTL3_EV_vs_WT_F08.05702.05702.2 0.000262 13/18 R.HNTAVSQLTK.A "sp|Q9NTJ3|SMC4_HUMAN,tr|E9PD53|E9PD53_HUMAN" 2 1097.5829 0.75 111692 5702 2 1097.5833 549.7987 Structural maintenance of chromosomes protein 4 OS=Homo sapiens OX=9606 GN=SMC4 PE=1 SV=2 8.76 1535.5 - 2.42E+06 - - - 0.3444 - 2.786 0.56 - 396.3 1 2 0 0.0004 10 0 0 0 2.32E+07 3.09E+07 - - - 6.037 0.9994 221125_WJC_METTL3_EV_vs_WT_F08.05709.05709.2 0.000733 22-Sep K.ASSQVNVEGQSR.L sp|O43665|RGS10_HUMAN 1 1260.6058 -1 111699 5709 2 1260.608278 631.3102 Regulator of G-protein signaling 10 OS=Homo sapiens OX=9606 GN=RGS10 PE=1 SV=3 6.05 1536.5 - 564367 - - - 1.9324 - 1.745 0.445 - 242.9 1 2 0 0.0024 12 0 0 0 0.00E+00 0.00E+00 - - - 3.7919 0.999 221125_WJC_METTL3_EV_vs_WT_F08.05712.05712.3 0.0359 Oct-36 K.VQVSYK[136.11]GETK[136.11].A "sp|P0DMV8|HS71A_HUMAN,sp|P0DMV9|HS71B_HUMAN,tr|A0A0G2JIW1|A0A0G2JIW1_HUMAN" 3 1153.6314 0.09 111701 5712 3 1153.631074 385.5511 Heat shock 70 kDa protein 1A OS=Homo sapiens OX=9606 GN=HSPA1A PE=1 SV=1 8.47 1536.8 - 1.01E+09 - - - -0.2731 - 2.001 0.355 - 198.8 1 2 1 -0.0003 10 0 0 0 4.34E+08 4.68E+09 - - - 4.5236 0.9984 221125_WJC_METTL3_EV_vs_WT_F08.05713.05713.2 1.58E-06 28-Dec R.SVQAGNPGGPGPGGR.G "sp|Q96AE4|FUBP1_HUMAN,tr|E9PEB5|E9PEB5_HUMAN" 2 1306.6378 1.76 111702 5713 2 1306.631469 654.3262 Far upstream element-binding protein 1 OS=Homo sapiens OX=9606 GN=FUBP1 PE=1 SV=3 9.47 1536.9 - 367369 - - - -4.8537 - 2.422 0.559 - 317.6 1 2 0 -0.0063 15 0 0 0 2.18E+06 1.23E+06 - - - 5.3426 0.9825 221125_WJC_METTL3_EV_vs_WT_F08.05717.05717.3 1.83E-05 Dec-40 F.RQDVDNASLAR.L "sp|P08670|VIME_HUMAN,tr|B0YJC5|B0YJC5_HUMAN,tr|B0YJC4|B0YJC4_HUMAN" 3 1243.6269 3.02 111706 5717 3 1243.624022 415.5496 Vimentin OS=Homo sapiens OX=9606 GN=VIM PE=1 SV=4 5.96 1537.1 - 5.19E+06 - - - -2.3238 - 1.927 0.456 - 241.1 1 1 0 -0.0029 11 0 0 0 2.70E+07 8.92E+06 - - - 5.4866 0.9947 221125_WJC_METTL3_EV_vs_WT_F08.05719.05719.2 0.155 18-Oct K.VQVSYK[136.11]GETK.A "sp|P0DMV8|HS71A_HUMAN,sp|P0DMV9|HS71B_HUMAN,tr|A0A0G2JIW1|A0A0G2JIW1_HUMAN" 3 1145.6172 - 111708 5719 2 1145.616627 573.8159 Heat shock 70 kDa protein 1A OS=Homo sapiens OX=9606 GN=HSPA1A PE=1 SV=1 8.47 1537.2 - 3.06E+06 - - - -0.4906 - 1.926 0.32 - 350.1 2 2 1 -0.0006 10 0 0 0 - - - - - 3.0994 1 221125_WJC_METTL3_EV_vs_WT_F08.05729.05729.2 5.52E-07 16/18 R.HNTAVSQLTK[136.11].A "sp|Q9NTJ3|SMC4_HUMAN,tr|E9PD53|E9PD53_HUMAN" 2 1105.5971 0.89 111715 5729 2 1105.595928 553.8058 Structural maintenance of chromosomes protein 4 OS=Homo sapiens OX=9606 GN=SMC4 PE=1 SV=2 8.76 1538.1 - 4.60E+06 - - - -1.08 - 3.185 0.638 - 716.2 1 2 0 -0.0012 10 0 0 0 2.78E+07 3.11E+07 - - - 6.9865 0.9969 221125_WJC_METTL3_EV_vs_WT_F08.05737.05737.2 0.0964 16-Sep R.DK[136.11]LSGEYEK[136.11].F "sp|P34932|HSP74_HUMAN,tr|A0A087WYC1|A0A087WYC1_HUMAN" 2 1083.5419 0.02 111723 5737 2 1083.541638 542.7782 Heat shock 70 kDa protein 4 OS=Homo sapiens OX=9606 GN=HSPA4 PE=1 SV=4 4.68 1539.1 - 1.01E+06 - - - -0.2464 - 1.779 0.398 - 257.7 1 2 1 -0.0003 9 0 0 0 1.28E+05 5.90E+06 - - - 3.6471 1 221125_WJC_METTL3_EV_vs_WT_F08.05743.05743.3 5.13E-06 Dec-44 R.HPEAEMAQNSVR.L sp|P14923|PLAK_HUMAN 1 1367.6252 18.4 111727 5743 3 1367.625913 456.8823 Junction plakoglobin OS=Homo sapiens OX=9606 GN=JUP PE=1 SV=3 5.4 1539.7 - 8.69E+06 - - - 0.5235 - 2.442 0.53 - 302 1 2 0 0.0007 12 0 0 0 9.51E+07 5.17E+06 - - - 6.9235 0.9897 221125_WJC_METTL3_EV_vs_WT_F08.05744.05744.3 0.000285 Dec-48 K.YEPAAVSEQGDKK.G sp|P05023|AT1A1_HUMAN 1 1420.6834 1.55 111728 5744 3 1420.682404 474.5684 Sodium\potassium-transporting ATPase subunit alpha-1 OS=Homo sapiens OX=9606 GN=ATP1A1 PE=1 SV=1 4.68 1539.7 - 4.58E+06 - - - -0.718 - 1.732 0.158 - 128.1 1 2 0 -0.001 13 0 0 0 2.57E+07 1.66E+07 - - - 1.7905 0.9997 221125_WJC_METTL3_EV_vs_WT_F08.05745.05745.3 0.000218 15/48 K.IQDK[136.11]EGIPPDQQR[166.11].L "sp|P62979|RS27A_HUMAN,sp|P0CG48|UBC_HUMAN,sp|P0CG48|UBC_HUMAN,sp|P0CG48|UBC_HUMAN,sp|P0CG48|UBC_HUMAN,sp|P0CG48|UBC_HUMAN,sp|P0CG48|UBC_HUMAN,sp|P0CG48|UBC_HUMAN,sp|P0CG48|UBC_HUMAN,sp|P0CG48|UBC_HUMAN,sp|P0CG47|UBB_HUMAN,sp|P0CG47|UBB_HUMAN,sp|P0CG47|UBB_HUMAN,sp|P62987|RL40_HUMAN,tr|F5H388|F5H388_HUMAN,tr|F5H388|F5H388_HUMAN,tr|F5GYU3|F5GYU3_HUMAN,tr|F5GYU3|F5GYU3_HUMAN,tr|B4DV12|B4DV12_HUMAN,tr|B4DV12|B4DV12_HUMAN,tr|J3QSA3|J3QSA3_HUMAN,tr|Q5PY61|Q5PY61_HUMAN,tr|Q5PY61|Q5PY61_HUMAN,tr|Q5PY61|Q5PY61_HUMAN,tr|F5H2Z3|F5H2Z3_HUMAN,tr|F5H2Z3|F5H2Z3_HUMAN,tr|M0R2S1|M0R2S1_HUMAN,tr|J3QS39|J3QS39_HUMAN,tr|J3QTR3|J3QTR3_HUMAN,tr|Q96C32|Q96C32_HUMAN,tr|Q96C32|Q96C32_HUMAN,tr|Q96C32|Q96C32_HUMAN,tr|Q96C32|Q96C32_HUMAN,tr|M0R1V7|M0R1V7_HUMAN,tr|F5H747|F5H747_HUMAN,tr|F5H747|F5H747_HUMAN,tr|F5GXK7|F5GXK7_HUMAN,tr|F5GXK7|F5GXK7_HUMAN,tr|M0R1M6|M0R1M6_HUMAN,tr|F5H6Q2|F5H6Q2_HUMAN,tr|F5H6Q2|F5H6Q2_HUMAN,tr|F5GZ39|F5GZ39_HUMAN,tr|J3QKN0|J3QKN0_HUMAN,tr|J3QKN0|J3QKN0_HUMAN,tr|F5H265|F5H265_HUMAN,tr|F5H265|F5H265_HUMAN,tr|A0A2R8Y422|A0A2R8Y422_HUMAN" 47 1540.7964 0.72 111729 5745 3 1540.795997 514.6061 Ubiquitin-40S ribosomal protein S27a OS=Homo sapiens OX=9606 GN=RPS27A PE=1 SV=2 4.56 1539.7 - 4.52E+06 - - - -0.2875 - 2.463 0.406 - 355.4 1 2 1 -0.0004 13 0 0 0 3.62E+08 5.05E+08 - - - 5.5103 0.9992 221125_WJC_METTL3_EV_vs_WT_F08.05748.05748.3 0.0035 13/48 K.IQDKEGIPPDQQR.L "sp|P62979|RS27A_HUMAN,sp|P0CG48|UBC_HUMAN,sp|P0CG48|UBC_HUMAN,sp|P0CG48|UBC_HUMAN,sp|P0CG48|UBC_HUMAN,sp|P0CG48|UBC_HUMAN,sp|P0CG48|UBC_HUMAN,sp|P0CG48|UBC_HUMAN,sp|P0CG48|UBC_HUMAN,sp|P0CG48|UBC_HUMAN,sp|P0CG47|UBB_HUMAN,sp|P0CG47|UBB_HUMAN,sp|P0CG47|UBB_HUMAN,sp|P62987|RL40_HUMAN,tr|F5H388|F5H388_HUMAN,tr|F5H388|F5H388_HUMAN,tr|F5GYU3|F5GYU3_HUMAN,tr|F5GYU3|F5GYU3_HUMAN,tr|B4DV12|B4DV12_HUMAN,tr|B4DV12|B4DV12_HUMAN,tr|J3QSA3|J3QSA3_HUMAN,tr|Q5PY61|Q5PY61_HUMAN,tr|Q5PY61|Q5PY61_HUMAN,tr|Q5PY61|Q5PY61_HUMAN,tr|F5H2Z3|F5H2Z3_HUMAN,tr|F5H2Z3|F5H2Z3_HUMAN,tr|M0R2S1|M0R2S1_HUMAN,tr|J3QS39|J3QS39_HUMAN,tr|J3QTR3|J3QTR3_HUMAN,tr|Q96C32|Q96C32_HUMAN,tr|Q96C32|Q96C32_HUMAN,tr|Q96C32|Q96C32_HUMAN,tr|Q96C32|Q96C32_HUMAN,tr|M0R1V7|M0R1V7_HUMAN,tr|F5H747|F5H747_HUMAN,tr|F5H747|F5H747_HUMAN,tr|F5GXK7|F5GXK7_HUMAN,tr|F5GXK7|F5GXK7_HUMAN,tr|M0R1M6|M0R1M6_HUMAN,tr|F5H6Q2|F5H6Q2_HUMAN,tr|F5H6Q2|F5H6Q2_HUMAN,tr|F5GZ39|F5GZ39_HUMAN,tr|J3QKN0|J3QKN0_HUMAN,tr|J3QKN0|J3QKN0_HUMAN,tr|F5H265|F5H265_HUMAN,tr|F5H265|F5H265_HUMAN,tr|A0A2R8Y422|A0A2R8Y422_HUMAN" 47 1522.774 0.72 111732 5748 3 1522.773252 508.5986 Ubiquitin-40S ribosomal protein S27a OS=Homo sapiens OX=9606 GN=RPS27A PE=1 SV=2 4.56 1539.9 - 3.39E+06 - - - -0.4715 - 2.271 0.355 - 258.3 1 2 1 -0.0007 13 0 0 0 3.59E+08 5.01E+08 - - - 4.7216 0.998 221125_WJC_METTL3_EV_vs_WT_F08.05750.05750.3 0.0291 Oct-40 R.AYQQKPYPSPK.T "sp|P39880|CUX1_HUMAN,tr|A0A2R8Y852|A0A2R8Y852_HUMAN,tr|A0A2R8YDI1|A0A2R8YDI1_HUMAN" 3 1305.6717 1.49 111734 5750 3 1305.672683 436.2312 Homeobox protein cut-like 1 OS=Homo sapiens OX=9606 GN=CUX1 PE=1 SV=3 9.53 1540 - 2.29E+06 - - - 0.7245 - 1.39 0.302 - 102.2 1 2 0 0.0009 11 0 0 0 3.23E+07 2.16E+07 - - - 2.8422 0.9998 221125_WJC_METTL3_EV_vs_WT_F08.05753.05753.2 2.09E-06 14/22 R.HPEAEMAQNSVR.L sp|P14923|PLAK_HUMAN 1 1367.6252 999 111737 5753 2 1367.623901 684.8199 Junction plakoglobin OS=Homo sapiens OX=9606 GN=JUP PE=1 SV=3 5.4 1540.2 - 1.61E+06 - - - -0.9476 - 2.165 0.478 - 460.1 1 2 0 -0.0013 12 0 0 0 1.69E+07 0.00E+00 - - - 4.6035 0.9922 221125_WJC_METTL3_EV_vs_WT_F08.05760.05760.3 0.0206 Oct-36 K.VQVEYK[136.11]GETK[136.11].T "sp|P54652|HSP72_HUMAN,sp|P11142|HSP7C_HUMAN,tr|E9PQQ4|E9PQQ4_HUMAN,tr|E9PKE3|E9PKE3_HUMAN,tr|E9PN89|E9PN89_HUMAN,tr|E9PLF4|E9PLF4_HUMAN,tr|E9PK54|E9PK54_HUMAN,tr|E9PN25|E9PN25_HUMAN,tr|E9PPY6|E9PPY6_HUMAN,tr|E9PQK7|E9PQK7_HUMAN" 10 1195.642 0.15 111742 5760 3 1195.640511 399.5546 Heat shock-related 70 kDa protein 2 OS=Homo sapiens OX=9606 GN=HSPA2 PE=1 SV=1 6.11 1541.1 - 5.27E+07 - - - -1.206 - 1.871 0.236 - 182.2 1 2 1 -0.0014 10 0 0 0 1.74E+08 1.17E+09 - - - 3.0003 0.9968 221125_WJC_METTL3_EV_vs_WT_F08.05762.05762.2 0.000843 18-Sep K.VQVEYK[136.11]GETK[136.11].T "sp|P54652|HSP72_HUMAN,sp|P11142|HSP7C_HUMAN,tr|E9PQQ4|E9PQQ4_HUMAN,tr|E9PKE3|E9PKE3_HUMAN,tr|E9PN89|E9PN89_HUMAN,tr|E9PLF4|E9PLF4_HUMAN,tr|E9PK54|E9PK54_HUMAN,tr|E9PN25|E9PN25_HUMAN,tr|E9PPY6|E9PPY6_HUMAN,tr|E9PQK7|E9PQK7_HUMAN" 10 1195.642 0.2 111744 5762 2 1195.641078 598.8283 Heat shock-related 70 kDa protein 2 OS=Homo sapiens OX=9606 GN=HSPA2 PE=1 SV=1 6.11 1541.1 - 6.03E+06 - - - -0.7318 - 1.798 0.411 - 360.3 1 2 1 -0.0009 10 0 0 0 3.16E+07 1.56E+08 - - - 3.714 0.9946 221125_WJC_METTL3_EV_vs_WT_F08.05763.05763.3 0.0131 Nov-36 R.AAQDRDQIYR.R "sp|P62995|TRA2B_HUMAN,tr|H7C2L4|H7C2L4_HUMAN" 2 1234.6054 1.57 111745 5763 3 1234.603302 412.5424 Transformer-2 protein homolog beta OS=Homo sapiens OX=9606 GN=TRA2B PE=1 SV=1 6 1541.2 - 4.84E+06 - - - -1.7382 - 2.202 0.237 - 295.3 1 2 1 -0.0021 10 0 0 0 2.41E+07 1.53E+07 - - - 3.487 0.7843 221125_WJC_METTL3_EV_vs_WT_F08.05770.05770.3 1.37 Jul-40 R.AYQQK[136.11]PYPSPK[136.11].T "sp|P39880|CUX1_HUMAN,tr|A0A2R8Y852|A0A2R8Y852_HUMAN,tr|A0A2R8YDI1|A0A2R8YDI1_HUMAN" 3 1321.7001 1.86 111752 5770 3 1321.701556 441.574 Homeobox protein cut-like 1 OS=Homo sapiens OX=9606 GN=CUX1 PE=1 SV=3 9.53 1541.6 - 1.82E+06 - - - 1.0736 - 1.226 0.082 - 43.8 1 2 0 0.0014 11 0 0 0 4.90E+07 2.64E+07 - - - 0.0327 1 221125_WJC_METTL3_EV_vs_WT_F08.05771.05771.2 1.85E-06 21/30 R.GGSGGSHGGGSGFGGE.S "sp|P35527|K1C9_HUMAN,tr|K7EQQ3|K7EQQ3_HUMAN" 2 1262.4912 - 111753 5771 2 1262.492975 632.2529 "Keratin, type I cytoskeletal 9 OS=Homo sapiens OX=9606 GN=KRT9 PE=1 SV=3" 5.47 1541.7 - 1.36E+06 - - - 1.4012 - 3.449 0.621 - 979 1 1 0 0.0018 16 0 0 0 - - - - - 6.671 0.9968 221125_WJC_METTL3_EV_vs_WT_F08.05773.05773.3 0.166 Aug-48 R.VALENDDR[166.11]SEEEK[136.11].Y "sp|Q99700|ATX2_HUMAN,tr|F8W0B5|F8W0B5_HUMAN,tr|A0A5F9ZHW5|A0A5F9ZHW5_HUMAN,tr|A0A5F9ZHH4|A0A5F9ZHH4_HUMAN,tr|A0A5F9ZI57|A0A5F9ZI57_HUMAN,tr|A0A2R8YDM9|A0A2R8YDM9_HUMAN,tr|F8VQP2|F8VQP2_HUMAN,tr|A0A2R8Y5A6|A0A2R8Y5A6_HUMAN,tr|F8WB06|F8WB06_HUMAN,tr|A0A5F9ZH85|A0A5F9ZH85_HUMAN,tr|F8VRK6|F8VRK6_HUMAN,tr|V9GY86|V9GY86_HUMAN,tr|A0A2R8Y7E6|A0A2R8Y7E6_HUMAN,tr|A0A5F9ZHX3|A0A5F9ZHX3_HUMAN,tr|H0YH87|H0YH87_HUMAN,tr|A0A2R8Y7P6|A0A2R8Y7P6_HUMAN" 16 1550.7179 0.86 111755 5773 3 1550.717352 517.9132 Ataxin-2 OS=Homo sapiens OX=9606 GN=ATXN2 PE=1 SV=2 4.08 1541.9 - 1.16E+06 - - - -0.3631 - 1.681 0.326 - 43.5 1 2 1 -0.0006 13 0 0 0 6.59E+06 7.66E+06 - - - 3.5826 0.9954 221125_WJC_METTL3_EV_vs_WT_F08.05777.05777.2 0.0108 13/20 K.NRVPSAGDVEK.A sp|Q15785|TOM34_HUMAN 1 1170.5993 0.74 111759 5777 2 1170.599591 586.3069 Mitochondrial import receptor subunit TOM34 OS=Homo sapiens OX=9606 GN=TOMM34 PE=1 SV=2 6.07 1542.4 - 874550 - - - 0.2486 - 2.191 0.282 - 316.1 1 2 1 0.0003 11 0 0 0 6.48E+06 8.73E+06 - - - 3.2456 0.9999 221125_WJC_METTL3_EV_vs_WT_F08.05779.05779.2 7.00E-07 20-Dec K.SC[160.03]NEQIEESEK[136.11].H "sp|Q99590|SCAFB_HUMAN,tr|F8VXG7|F8VXG7_HUMAN,tr|A0A0A0MTP7|A0A0A0MTP7_HUMAN" 3 1359.5704 0.99 111761 5779 2 1359.569879 680.7925 Protein SCAF11 OS=Homo sapiens OX=9606 GN=SCAF11 PE=1 SV=2 4.09 1542.7 - 688347 - - - -0.3648 - 2.179 0.584 - 581.2 1 2 0 -0.0005 11 0 0 0 3.54E+06 3.56E+06 - - - 5.4613 0.9996 221125_WJC_METTL3_EV_vs_WT_F08.05781.05781.3 0.0011 Oct-36 R.SR[166.11]QEDPEQLR[166.11].L "sp|O00268|TAF4_HUMAN,tr|A0A0G2JRY5|A0A0G2JRY5_HUMAN,tr|V9GY03|V9GY03_HUMAN" 3 1276.6275 1.48 111762 5781 3 1276.628019 426.5498 Transcription initiation factor TFIID subunit 4 OS=Homo sapiens OX=9606 GN=TAF4 PE=1 SV=2 4.68 1542.9 - 1.26E+06 - - - 0.4316 - 2.181 0.396 - 313.2 1 2 1 0.0006 10 0 0 0 6.77E+07 4.58E+07 - - - 5.2322 0.9999 221125_WJC_METTL3_EV_vs_WT_F08.05786.05786.3 0.000379 16/48 R.TKTPGPGAQSALR.A "sp|P62263|RS14_HUMAN,tr|A0A2R8Y811|A0A2R8Y811_HUMAN,tr|E5RH77|E5RH77_HUMAN" 3 1282.6993 1.3 111767 5786 3 1282.698474 428.5737 40S ribosomal protein S14 OS=Homo sapiens OX=9606 GN=RPS14 PE=1 SV=3 11 1543.1 - 5.03E+06 - - - -0.6822 - 3.442 0.504 - 446 1 2 1 -0.0009 13 0 0 0 1.64E+09 1.25E+09 - - - 7.5102 1 221125_WJC_METTL3_EV_vs_WT_F08.05787.05787.3 8.91E-05 Oct-44 R.C[160.03]GSSEDLHDSVR.E sp|Q7Z4V5|HDGR2_HUMAN 1 1360.5677 1.13 111768 5787 3 1360.567209 454.5299 Hepatoma-derived growth factor-related protein 2 OS=Homo sapiens OX=9606 GN=HDGFL2 PE=1 SV=1 4.54 1543.2 - 2.48E+06 - - - -0.3917 - 1.878 0.563 - 157.8 1 2 0 -0.0005 12 0 0 0 1.16E+07 1.03E+07 - - - 6.5636 0.9914 221125_WJC_METTL3_EV_vs_WT_F08.05789.05789.2 0.00036 20-Dec P.GEVAGTVTGQK[136.11].R "sp|Q86U44|MTA70_HUMAN,tr|F5H6D8|F5H6D8_HUMAN,tr|H0YFV6|H0YFV6_HUMAN,tr|B4DTN4|B4DTN4_HUMAN" 4 1053.5546 0 111770 5789 2 1053.553707 527.7846 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 6 1543.3 - 1.74E+06 - - - -0.8362 - 2.484 0.44 - 580.3 1 1 0 -0.0009 11 0 0 0 2.37E+05 8.01E+07 - - - 4.752 0.9999 221125_WJC_METTL3_EV_vs_WT_F08.05791.05791.2 1.22E-05 20-Dec K.NSC[160.03]VQQSDNLK.V sp|Q92576|PHF3_HUMAN 1 1291.5827 0.92 111772 5791 2 1291.581752 646.7986 PHD finger protein 3 OS=Homo sapiens OX=9606 GN=PHF3 PE=1 SV=3 5.83 1543.5 - 1.37E+06 - - - -0.7061 - 2.343 0.509 - 730.1 1 2 0 -0.0009 11 0 0 0 5.78E+06 6.26E+06 - - - 5.1035 0.9998 221125_WJC_METTL3_EV_vs_WT_F08.05792.05792.2 3.61E-06 20-Dec K.NSC[160.03]VQQSDNLK[136.11].V sp|Q92576|PHF3_HUMAN 1 1299.5969 0.92 111773 5792 2 1299.596666 650.8057 PHD finger protein 3 OS=Homo sapiens OX=9606 GN=PHF3 PE=1 SV=3 5.83 1543.6 - 1.28E+06 - - - -0.1524 - 2.091 0.457 - 680.8 1 2 0 -0.0002 11 0 0 0 5.78E+06 6.26E+06 - - - 4.4118 0.9163 221125_WJC_METTL3_EV_vs_WT_F08.05793.05793.2 0.493 20-Dec K.NR[166.11]VPSAGDVEK[136.11].A sp|Q15785|TOM34_HUMAN 1 1188.6218 0.69 111774 5793 2 1188.622576 595.3182 Mitochondrial import receptor subunit TOM34 OS=Homo sapiens OX=9606 GN=TOMM34 PE=1 SV=2 6.07 1543.7 - 1.15E+06 - - - 0.6781 - 1.657 0.062 - 343.5 1 2 1 0.0008 11 0 0 0 5.49E+06 7.99E+06 - - - 0.8648 1 221125_WJC_METTL3_EV_vs_WT_F08.05794.05794.2 5.98E-05 15/24 K.IQDK[136.11]EGIPPDQQR[166.11].L "sp|P62979|RS27A_HUMAN,sp|P0CG48|UBC_HUMAN,sp|P0CG48|UBC_HUMAN,sp|P0CG48|UBC_HUMAN,sp|P0CG48|UBC_HUMAN,sp|P0CG48|UBC_HUMAN,sp|P0CG48|UBC_HUMAN,sp|P0CG48|UBC_HUMAN,sp|P0CG48|UBC_HUMAN,sp|P0CG48|UBC_HUMAN,sp|P0CG47|UBB_HUMAN,sp|P0CG47|UBB_HUMAN,sp|P0CG47|UBB_HUMAN,sp|P62987|RL40_HUMAN,tr|F5H388|F5H388_HUMAN,tr|F5H388|F5H388_HUMAN,tr|F5GYU3|F5GYU3_HUMAN,tr|F5GYU3|F5GYU3_HUMAN,tr|B4DV12|B4DV12_HUMAN,tr|B4DV12|B4DV12_HUMAN,tr|J3QSA3|J3QSA3_HUMAN,tr|Q5PY61|Q5PY61_HUMAN,tr|Q5PY61|Q5PY61_HUMAN,tr|Q5PY61|Q5PY61_HUMAN,tr|F5H2Z3|F5H2Z3_HUMAN,tr|F5H2Z3|F5H2Z3_HUMAN,tr|M0R2S1|M0R2S1_HUMAN,tr|J3QS39|J3QS39_HUMAN,tr|J3QTR3|J3QTR3_HUMAN,tr|Q96C32|Q96C32_HUMAN,tr|Q96C32|Q96C32_HUMAN,tr|Q96C32|Q96C32_HUMAN,tr|Q96C32|Q96C32_HUMAN,tr|M0R1V7|M0R1V7_HUMAN,tr|F5H747|F5H747_HUMAN,tr|F5H747|F5H747_HUMAN,tr|F5GXK7|F5GXK7_HUMAN,tr|F5GXK7|F5GXK7_HUMAN,tr|M0R1M6|M0R1M6_HUMAN,tr|F5H6Q2|F5H6Q2_HUMAN,tr|F5H6Q2|F5H6Q2_HUMAN,tr|F5GZ39|F5GZ39_HUMAN,tr|J3QKN0|J3QKN0_HUMAN,tr|J3QKN0|J3QKN0_HUMAN,tr|F5H265|F5H265_HUMAN,tr|F5H265|F5H265_HUMAN,tr|A0A2R8Y422|A0A2R8Y422_HUMAN" 47 1540.7964 0.62 111775 5794 2 1540.793758 771.4055 Ubiquitin-40S ribosomal protein S27a OS=Homo sapiens OX=9606 GN=RPS27A PE=1 SV=2 4.56 1543.9 - 1.08E+06 - - - -1.7407 - 2.984 0.531 - 581.6 1 2 1 -0.0027 13 0 0 0 2.39E+07 3.89E+07 - - - 5.768 1 221125_WJC_METTL3_EV_vs_WT_F08.05795.05795.2 4.18E-05 16/24 K.SELGNQSPSTSSR.Q "sp|Q5JTV8|TOIP1_HUMAN,tr|H0YD16|H0YD16_HUMAN,tr|J3KN66|J3KN66_HUMAN,tr|A0A0A0MSK5|A0A0A0MSK5_HUMAN" 4 1348.6219 1.05 111776 5795 2 1348.621156 675.3182 Torsin-1A-interacting protein 1 OS=Homo sapiens OX=9606 GN=TOR1AIP1 PE=1 SV=2 5.72 1544 - 1.06E+06 - - - -0.5413 - 3.123 0.525 - 977.2 1 2 0 -0.0007 13 0 0 0 1.61E+07 1.53E+07 - - - 5.8412 0.9989 221125_WJC_METTL3_EV_vs_WT_F08.05802.05802.3 0.0392 Nov-36 K.VSELK[136.11]EELK[136.11]K[136.11].R "sp|Q00839|HNRPU_HUMAN,tr|A0A1W2PPS1|A0A1W2PPS1_HUMAN,tr|A0A1X7SBS1|A0A1X7SBS1_HUMAN" 3 1225.7344 0.98 111781 5802 3 1225.732224 409.5854 Heterogeneous nuclear ribonucleoprotein U OS=Homo sapiens OX=9606 GN=HNRNPU PE=1 SV=6 6.2 1544.7 - 1.42E+07 - - - -1.7785 - 1.97 0.381 - 129.9 1 2 1 -0.0022 10 0 0 0 2.86E+09 2.92E+09 - - - 4.7673 0.9994 221125_WJC_METTL3_EV_vs_WT_F08.05803.05803.3 0.00262 16/40 R.LKMEGHEAMER.L "sp|Q8WXI9|P66B_HUMAN,tr|A0A0U1RR34|A0A0U1RR34_HUMAN,tr|A0A0U1RRM1|A0A0U1RRM1_HUMAN,tr|A0A0U1RRK3|A0A0U1RRK3_HUMAN" 4 1329.6169 1.2 111782 5803 3 1329.614115 444.2129 Transcriptional repressor p66-beta OS=Homo sapiens OX=9606 GN=GATAD2B PE=1 SV=1 5.5 1544.8 - 4.60E+06 - - - -2.1254 - 2.809 0.369 - 321.4 1 2 1 -0.0028 11 0 0 0 1.89E+07 1.57E+07 - - - 5.5873 1 221125_WJC_METTL3_EV_vs_WT_F08.05807.05807.2 6.03E-05 16/18 R.R[166.11]TAQEVETYR[166.11].R "sp|P17844|DDX5_HUMAN,tr|J3QR02|J3QR02_HUMAN,tr|A0A7I2V507|A0A7I2V507_HUMAN,tr|J3KTA4|J3KTA4_HUMAN,tr|J3KTQ4|J3KTQ4_HUMAN,tr|A0A7I2V2S0|A0A7I2V2S0_HUMAN,tr|J3QRQ7|J3QRQ7_HUMAN" 7 1271.6373 1.79 111786 5807 2 1271.636247 636.8259 Probable ATP-dependent RNA helicase DDX5 OS=Homo sapiens OX=9606 GN=DDX5 PE=1 SV=1 6.14 1545.1 - 2.68E+06 - - - -0.8312 - 2.962 0.532 - 415.7 1 2 0 -0.0011 10 0 0 0 1.67E+07 9.35E+06 - - - 6.001 0.9997 221125_WJC_METTL3_EV_vs_WT_F08.05808.05808.3 2.09E-05 Dec-36 R.HLNPDTELK[136.11]R[166.11].Y "sp|Q9BQ70|TCF25_HUMAN,tr|Q9H7D3|Q9H7D3_HUMAN,tr|H3BSS3|H3BSS3_HUMAN,tr|H3BQ53|H3BQ53_HUMAN,tr|H3BSP8|H3BSP8_HUMAN" 5 1239.6691 0.89 111787 5808 3 1239.667873 414.2303 Transcription factor 25 OS=Homo sapiens OX=9606 GN=TCF25 PE=1 SV=1 6.75 1545.1 - 1.66E+06 - - - -0.9535 - 2.279 0.298 - 217.4 1 2 0 -0.0012 10 0 0 0 1.41E+07 1.58E+07 - - - 4.2678 0.9945 221125_WJC_METTL3_EV_vs_WT_F08.05809.05809.2 0.00142 13/24 R.TKTPGPGAQSALR.A "sp|P62263|RS14_HUMAN,tr|A0A2R8Y811|A0A2R8Y811_HUMAN,tr|E5RH77|E5RH77_HUMAN" 3 1282.6993 1.29 111788 5809 2 1282.698394 642.357 40S ribosomal protein S14 OS=Homo sapiens OX=9606 GN=RPS14 PE=1 SV=3 11 1545.2 - 1.61E+06 - - - -0.7445 - 2.089 0.297 - 481.4 1 2 1 -0.001 13 0 0 0 1.97E+08 1.53E+08 - - - 3.1251 0.9999 221125_WJC_METTL3_EV_vs_WT_F08.05810.05810.2 3.18E-07 17/24 K.SELGNQSPSTSSR[166.11].Q "sp|Q5JTV8|TOIP1_HUMAN,tr|H0YD16|H0YD16_HUMAN,tr|J3KN66|J3KN66_HUMAN,tr|A0A0A0MSK5|A0A0A0MSK5_HUMAN" 4 1358.6302 1.05 111789 5810 2 1358.62978 680.3224 Torsin-1A-interacting protein 1 OS=Homo sapiens OX=9606 GN=TOR1AIP1 PE=1 SV=2 5.72 1545.4 - 1.39E+06 - - - -0.2767 - 3.245 0.492 - 1107.9 1 2 0 -0.0004 13 0 0 0 1.61E+07 1.53E+07 - - - 5.6959 0.9981 221125_WJC_METTL3_EV_vs_WT_F08.05811.05811.2 0.0104 14/18 K.VSELK[136.11]EELK[136.11]K[136.11].R "sp|Q00839|HNRPU_HUMAN,tr|A0A1W2PPS1|A0A1W2PPS1_HUMAN,tr|A0A1X7SBS1|A0A1X7SBS1_HUMAN" 3 1225.7344 1.06 111790 5811 2 1225.736561 613.8745 Heterogeneous nuclear ribonucleoprotein U OS=Homo sapiens OX=9606 GN=HNRNPU PE=1 SV=6 6.2 1545.5 - 1.01E+06 - - - 1.7598 - 2.737 0.503 - 639.7 1 2 1 0.0022 10 0 0 0 3.30E+08 3.10E+08 - - - 5.5659 0.9964 221125_WJC_METTL3_EV_vs_WT_F08.05812.05812.2 0.00962 22-Nov K.LEVQATDR[166.11]EENK[136.11].Q "sp|P11387|TOP1_HUMAN,tr|A0A7P0T852|A0A7P0T852_HUMAN" 2 1448.7226 -1 111791 5812 2 1448.721214 725.3686 DNA topoisomerase 1 OS=Homo sapiens OX=9606 GN=TOP1 PE=1 SV=2 4.41 1545.6 - 967356 - - - -0.9615 - 1.975 0.385 - 329.7 1 2 1 -0.0014 12 0 0 0 0.00E+00 0.00E+00 - - - 3.6749 1 221125_WJC_METTL3_EV_vs_WT_F08.05818.05818.3 2.26E-05 17/44 R.R[166.11]APDQAAEIGSR[166.11].G "sp|Q3ZCQ8|TIM50_HUMAN,tr|M0R1Y4|M0R1Y4_HUMAN,tr|M0QXC3|M0QXC3_HUMAN,tr|M0R303|M0R303_HUMAN,tr|M0R2D2|M0R2D2_HUMAN,tr|M0R003|M0R003_HUMAN,tr|M0R2Z3|M0R2Z3_HUMAN" 7 1289.6591 0.94 111796 5818 3 1289.656746 430.8936 Mitochondrial import inner membrane translocase subunit TIM50 OS=Homo sapiens OX=9606 GN=TIMM50 PE=1 SV=2 6.07 1546.2 - 3.91E+06 - - - -1.8268 - 2.929 0.49 - 473.1 1 2 0 -0.0024 12 0 0 0 1.07E+08 1.14E+08 - - - 6.9812 0.9996 221125_WJC_METTL3_EV_vs_WT_F08.05819.05819.3 0.00069 Dec-36 K.VSELKEELKK.R "sp|Q00839|HNRPU_HUMAN,tr|A0A1W2PPS1|A0A1W2PPS1_HUMAN,tr|A0A1X7SBS1|A0A1X7SBS1_HUMAN" 3 1201.6918 0.98 111797 5819 3 1201.690896 401.5712 Heterogeneous nuclear ribonucleoprotein U OS=Homo sapiens OX=9606 GN=HNRNPU PE=1 SV=6 6.2 1546.3 - 9.43E+07 - - - -0.7556 - 2.374 0.376 - 189.1 1 2 1 -0.0009 10 0 0 0 2.86E+09 2.92E+09 - - - 5.2567 1 221125_WJC_METTL3_EV_vs_WT_F08.05821.05821.2 7.30E-07 15/28 K.GGSISGGGYGSGGGK.H sp|P35908|K22E_HUMAN 1 1196.5422 999 111799 5821 2 1196.541202 599.2784 "Keratin, type II cytoskeletal 2 epidermal OS=Homo sapiens OX=9606 GN=KRT2 PE=1 SV=2" 8.59 1546.3 - 3.38E+07 - - - -0.8165 - 2.664 0.634 - 611.8 1 2 0 -0.001 15 0 0 0 1.21E+09 0.00E+00 - - - 6.1324 0.98 221125_WJC_METTL3_EV_vs_WT_F08.05823.05823.2 4.39E-05 14-Sep P.DAHSDYAR.Y sp|Q96PK6|RBM14_HUMAN 1 933.3941 2.41 111801 5823 2 933.393097 467.7043 RNA-binding protein 14 OS=Homo sapiens OX=9606 GN=RBM14 PE=1 SV=2 5.21 1546.4 - 1.46E+07 - - - -1.0296 - 1.682 0.413 - 254.7 1 1 0 -0.001 8 0 0 0 2.34E+08 9.70E+07 - - - 3.6594 0.8373 221125_WJC_METTL3_EV_vs_WT_F08.05824.05824.2 0.0405 16-Dec V.SELK[136.11]EELK[136.11]K[136.11].R "sp|Q00839|HNRPU_HUMAN,tr|A0A1W2PPS1|A0A1W2PPS1_HUMAN,tr|A0A1X7SBS1|A0A1X7SBS1_HUMAN" 3 1126.666 1.07 111802 5824 2 1126.665 564.3403 Heterogeneous nuclear ribonucleoprotein U OS=Homo sapiens OX=9606 GN=HNRNPU PE=1 SV=6 5.95 1546.5 - 7.82E+06 - - - -0.8787 - 2.149 0.342 - 449.7 1 1 1 -0.001 9 0 0 0 2.04E+08 1.91E+08 - - - 3.7799 0.9985 221125_WJC_METTL3_EV_vs_WT_F08.05825.05825.2 0.0014 15/18 K.VSELKEELKK.R "sp|Q00839|HNRPU_HUMAN,tr|A0A1W2PPS1|A0A1W2PPS1_HUMAN,tr|A0A1X7SBS1|A0A1X7SBS1_HUMAN" 3 1201.6918 1.06 111803 5825 2 1201.690558 601.8532 Heterogeneous nuclear ribonucleoprotein U OS=Homo sapiens OX=9606 GN=HNRNPU PE=1 SV=6 6.2 1546.5 - 6.98E+06 - - - -1.0369 - 2.864 0.413 - 800.1 1 2 1 -0.0012 10 0 0 0 3.30E+08 3.10E+08 - - - 5.0281 1 221125_WJC_METTL3_EV_vs_WT_F08.05826.05826.2 2.23E-06 19/20 R.RLPDAHSDYAR.Y sp|Q96PK6|RBM14_HUMAN 1 1299.632 2.02 111804 5826 2 1299.630991 650.8233 RNA-binding protein 14 OS=Homo sapiens OX=9606 GN=RBM14 PE=1 SV=2 6.75 1546.6 - 6.33E+06 - - - -0.7741 - 3.089 0.569 - 789.7 1 2 0 -0.001 11 0 0 0 1.42E+08 7.05E+07 - - - 6.2944 0.8711 221125_WJC_METTL3_EV_vs_WT_F08.05827.05827.2 0.00691 14/16 V.SELKEELKK.R "sp|Q00839|HNRPU_HUMAN,tr|A0A1W2PPS1|A0A1W2PPS1_HUMAN,tr|A0A1X7SBS1|A0A1X7SBS1_HUMAN" 3 1102.6234 1.07 111805 5827 2 1102.622587 552.319 Heterogeneous nuclear ribonucleoprotein U OS=Homo sapiens OX=9606 GN=HNRNPU PE=1 SV=6 5.95 1546.6 - 6.12E+06 - - - -0.7283 - 2.501 0.321 - 705.6 1 1 1 -0.0008 9 0 0 0 2.04E+08 1.91E+08 - - - 4.0637 0.9989 221125_WJC_METTL3_EV_vs_WT_F08.05830.05830.3 1.47 13/36 K.VSELK[136.11]EELKK[136.11].R "sp|Q00839|HNRPU_HUMAN,tr|A0A1W2PPS1|A0A1W2PPS1_HUMAN,tr|A0A1X7SBS1|A0A1X7SBS1_HUMAN" 3 1217.7202 - 111808 5830 3 1217.718916 406.914 Heterogeneous nuclear ribonucleoprotein U OS=Homo sapiens OX=9606 GN=HNRNPU PE=1 SV=6 6.2 1546.7 - 4.08E+06 - - - -1.0577 - 2.367 0.304 - 244.5 1 2 1 -0.0013 10 0 0 0 - - - - - 4.4453 0.9996 221125_WJC_METTL3_EV_vs_WT_F08.05831.05831.3 0.00724 Nov-48 K.TTHFVEGGDAGNR.E "sp|P18124|RL7_HUMAN,tr|A8MUD9|A8MUD9_HUMAN" 2 1359.6167 1.2 111809 5831 3 1359.614203 454.2129 60S ribosomal protein L7 OS=Homo sapiens OX=9606 GN=RPL7 PE=1 SV=1 5.29 1546.8 - 4.00E+06 - - - -1.8667 - 1.612 0.414 - 205.2 1 2 0 -0.0025 13 0 0 0 4.62E+07 3.84E+07 - - - 4.4496 0.9999 221125_WJC_METTL3_EV_vs_WT_F08.05832.05832.2 6.59E-06 14/20 R.R[166.11]LPDAHSDYAR[166.11].Y sp|Q96PK6|RBM14_HUMAN 1 1319.6485 2.02 111810 5832 2 1319.64872 660.8315 RNA-binding protein 14 OS=Homo sapiens OX=9606 GN=RBM14 PE=1 SV=2 6.75 1546.8 - 3.70E+06 - - - 0.1387 - 2.799 0.495 - 290.5 1 2 0 0.0002 11 0 0 0 1.42E+08 7.05E+07 - - - 5.4814 0.815 221125_WJC_METTL3_EV_vs_WT_F08.05833.05833.2 0.797 14-Sep V.K[136.11]LEEELK[136.11]K[136.11].K "sp|Q4VCS5|AMOT_HUMAN,tr|A6NP16|A6NP16_HUMAN,tr|E7ERM3|E7ERM3_HUMAN" 3 1039.634 1.12 111811 5833 2 1039.633053 520.8243 Angiomotin OS=Homo sapiens OX=9606 GN=AMOT PE=1 SV=1 6.23 1546.9 - 3.19E+06 - - - -0.8734 - 1.558 0.139 - 258.8 1 1 0 -0.0009 8 0 0 0 7.40E+07 6.59E+07 - - - 1.4047 0.9999 221125_WJC_METTL3_EV_vs_WT_F08.05838.05838.2 3.37E-07 16/22 R.RYPSSISSSPQK.D "sp|Q14157|UBP2L_HUMAN,tr|F8W726|F8W726_HUMAN" 2 1335.6783 2.21 111815 5838 2 1335.678495 668.8464 Ubiquitin-associated protein 2-like OS=Homo sapiens OX=9606 GN=UBAP2L PE=1 SV=2 9.99 1547.3 - 3.16E+06 - - - 0.1617 - 2.817 0.527 - 562.7 1 2 0 0.0002 12 0 0 0 8.27E+07 3.74E+07 - - - 5.6584 0.9774 221125_WJC_METTL3_EV_vs_WT_F08.05841.05841.2 7.00E-06 14-Oct P.DAHSDYAR[166.11].Y sp|Q96PK6|RBM14_HUMAN 1 943.4023 2.41 111818 5841 2 943.40219 472.7084 RNA-binding protein 14 OS=Homo sapiens OX=9606 GN=RBM14 PE=1 SV=2 5.21 1547.5 - 1.88E+07 - - - -0.1463 - 1.814 0.332 - 307.9 1 1 0 -0.0001 8 0 0 0 2.34E+08 9.70E+07 - - - 3.2892 0.9998 221125_WJC_METTL3_EV_vs_WT_F08.05842.05842.3 1.12E-05 15/44 R.RAPDQAAEIGSR.G "sp|Q3ZCQ8|TIM50_HUMAN,tr|M0R1Y4|M0R1Y4_HUMAN,tr|M0QXC3|M0QXC3_HUMAN,tr|M0R303|M0R303_HUMAN,tr|M0R2D2|M0R2D2_HUMAN,tr|M0R003|M0R003_HUMAN,tr|M0R2Z3|M0R2Z3_HUMAN" 7 1269.6426 0.98 111819 5842 3 1269.637375 424.2215 Mitochondrial import inner membrane translocase subunit TIM50 OS=Homo sapiens OX=9606 GN=TIMM50 PE=1 SV=2 6.07 1547.5 - 5.98E+06 - - - -4.0854 - 3.023 0.462 - 480.6 1 2 0 -0.0052 12 0 0 0 1.07E+08 1.10E+08 - - - 6.7558 0.9988 221125_WJC_METTL3_EV_vs_WT_F08.05846.05846.2 6.04E-07 17/24 K.IQDKEGIPPDQQR.L "sp|P62979|RS27A_HUMAN,sp|P0CG48|UBC_HUMAN,sp|P0CG48|UBC_HUMAN,sp|P0CG48|UBC_HUMAN,sp|P0CG48|UBC_HUMAN,sp|P0CG48|UBC_HUMAN,sp|P0CG48|UBC_HUMAN,sp|P0CG48|UBC_HUMAN,sp|P0CG48|UBC_HUMAN,sp|P0CG48|UBC_HUMAN,sp|P0CG47|UBB_HUMAN,sp|P0CG47|UBB_HUMAN,sp|P0CG47|UBB_HUMAN,sp|P62987|RL40_HUMAN,tr|F5H388|F5H388_HUMAN,tr|F5H388|F5H388_HUMAN,tr|F5GYU3|F5GYU3_HUMAN,tr|F5GYU3|F5GYU3_HUMAN,tr|B4DV12|B4DV12_HUMAN,tr|B4DV12|B4DV12_HUMAN,tr|J3QSA3|J3QSA3_HUMAN,tr|Q5PY61|Q5PY61_HUMAN,tr|Q5PY61|Q5PY61_HUMAN,tr|Q5PY61|Q5PY61_HUMAN,tr|F5H2Z3|F5H2Z3_HUMAN,tr|F5H2Z3|F5H2Z3_HUMAN,tr|M0R2S1|M0R2S1_HUMAN,tr|J3QS39|J3QS39_HUMAN,tr|J3QTR3|J3QTR3_HUMAN,tr|Q96C32|Q96C32_HUMAN,tr|Q96C32|Q96C32_HUMAN,tr|Q96C32|Q96C32_HUMAN,tr|Q96C32|Q96C32_HUMAN,tr|M0R1V7|M0R1V7_HUMAN,tr|F5H747|F5H747_HUMAN,tr|F5H747|F5H747_HUMAN,tr|F5GXK7|F5GXK7_HUMAN,tr|F5GXK7|F5GXK7_HUMAN,tr|M0R1M6|M0R1M6_HUMAN,tr|F5H6Q2|F5H6Q2_HUMAN,tr|F5H6Q2|F5H6Q2_HUMAN,tr|F5GZ39|F5GZ39_HUMAN,tr|J3QKN0|J3QKN0_HUMAN,tr|J3QKN0|J3QKN0_HUMAN,tr|F5H265|F5H265_HUMAN,tr|F5H265|F5H265_HUMAN,tr|A0A2R8Y422|A0A2R8Y422_HUMAN" 47 1522.774 0.57 111823 5846 2 1522.772059 762.3943 Ubiquitin-40S ribosomal protein S27a OS=Homo sapiens OX=9606 GN=RPS27A PE=1 SV=2 4.56 1548 - 1.87E+06 - - - -1.2549 - 3.14 0.505 - 804.7 1 2 1 -0.0019 13 0 0 0 2.20E+07 3.87E+07 - - - 5.707 0.9977 221125_WJC_METTL3_EV_vs_WT_F08.05848.05848.2 0.000118 16/22 R.RAPDQAAEIGSR.G "sp|Q3ZCQ8|TIM50_HUMAN,tr|M0R1Y4|M0R1Y4_HUMAN,tr|M0QXC3|M0QXC3_HUMAN,tr|M0R303|M0R303_HUMAN,tr|M0R2D2|M0R2D2_HUMAN,tr|M0R003|M0R003_HUMAN,tr|M0R2Z3|M0R2Z3_HUMAN" 7 1269.6426 1.15 111825 5848 2 1269.636217 635.8286 Mitochondrial import inner membrane translocase subunit TIM50 OS=Homo sapiens OX=9606 GN=TIMM50 PE=1 SV=2 6.07 1548.2 - 1.58E+06 - - - -4.9975 - 2.558 0.456 - 288.8 1 2 0 -0.0063 12 0 0 0 1.50E+07 1.31E+07 - - - 4.8783 0.9995 221125_WJC_METTL3_EV_vs_WT_F08.05849.05849.2 0.000148 18-Oct R.QEMQEVQSSR[166.11].S "sp|P22626|ROA2_HUMAN,tr|A0A024RA28|A0A024RA28_HUMAN,tr|A0A7I2V4N1|A0A7I2V4N1_HUMAN,tr|A0A7I2V4I6|A0A7I2V4I6_HUMAN,tr|A0A7I2V4S4|A0A7I2V4S4_HUMAN,tr|A0A7I2V323|A0A7I2V323_HUMAN,tr|A0A7I2V3P1|A0A7I2V3P1_HUMAN,tr|A0A7I2V3P7|A0A7I2V3P7_HUMAN" 8 1230.5538 4.89 111826 5849 2 1230.550798 616.2842 Heterogeneous nuclear ribonucleoproteins A2\B1 OS=Homo sapiens OX=9606 GN=HNRNPA2B1 PE=1 SV=2 4.53 1548.3 - 2.71E+06 - - - -2.4558 - 2.125 0.444 - 244.3 1 2 0 -0.003 10 0 0 0 3.54E+07 7.24E+06 - - - 4.4234 0.9996 221125_WJC_METTL3_EV_vs_WT_F08.05850.05850.2 3.87E-06 22-Dec R.GGSGSHNWGTVK.D sp|Q8NC51|PAIRB_HUMAN 1 1185.5527 0.62 111827 5850 2 1185.548959 593.7836 Plasminogen activator inhibitor 1 RNA-binding protein OS=Homo sapiens OX=9606 GN=SERBP1 PE=1 SV=2 8.76 1548.4 - 1.32E+06 - - - -3.142 - 2.608 0.562 - 417.6 1 2 0 -0.0037 12 0 0 0 1.69E+07 2.73E+07 - - - 5.713 0.8894 221125_WJC_METTL3_EV_vs_WT_F08.05851.05851.2 0.00023 22-Sep K.GEVDVTHDSEPK.N sp|Q9NV35|NUD15_HUMAN 1 1311.5943 12.33 111828 5851 2 1312.592062 656.8044 Nucleotide triphosphate diphosphatase NUDT15 OS=Homo sapiens OX=9606 GN=NUDT15 PE=1 SV=1 4.31 1548.6 - 0 - - - 760.7444 - 1.57 0.511 - 209.4 1 2 0 0.9978 12 0 0 0 2.26E+06 1.83E+05 - - - 3.6888 0.8816 221125_WJC_METTL3_EV_vs_WT_F08.05860.05860.2 0.19 18-Sep V.KLEGPDVSLK.G sp|Q09666|AHNK_HUMAN 1 1084.6128 999 111835 5860 2 1084.611931 543.3137 Neuroblast differentiation-associated protein AHNAK OS=Homo sapiens OX=9606 GN=AHNAK PE=1 SV=2 6.07 1549.4 - 1.31E+06 - - - -0.8243 - 1.614 0.192 - 159.6 1 1 0 -0.0009 10 0 0 0 6.75E+06 0.00E+00 - - - 1.7951 0.9998 221125_WJC_METTL3_EV_vs_WT_F08.05864.05864.3 0.00229 Nov-44 R.RYPSSISSSPQK.D "sp|Q14157|UBP2L_HUMAN,tr|F8W726|F8W726_HUMAN" 2 1335.6783 2.03 111837 5864 3 1335.675158 446.2334 Ubiquitin-associated protein 2-like OS=Homo sapiens OX=9606 GN=UBAP2L PE=1 SV=2 9.99 1549.9 - 1.48E+07 - - - -2.3366 - 1.96 0.429 - 197.4 1 2 0 -0.0031 12 0 0 0 1.93E+08 9.50E+07 - - - 5.1874 0.9998 221125_WJC_METTL3_EV_vs_WT_F08.05865.05865.2 0.0003 18-Sep K.SQESNVSIQK.E "sp|Q15643|TRIPB_HUMAN,tr|H0YJ97|H0YJ97_HUMAN" 2 1118.5568 1.15 111838 5865 2 1118.555536 560.2857 Thyroid receptor-interacting protein 11 OS=Homo sapiens OX=9606 GN=TRIP11 PE=1 SV=3 5.72 1550 - 1.76E+07 - - - -1.1005 - 2.086 0.474 - 337 1 2 0 -0.0012 10 0 0 0 2.21E+08 1.92E+08 - - - 4.5939 1 221125_WJC_METTL3_EV_vs_WT_F08.05867.05867.2 3.25E-10 14/24 R.NPQNSSQSADGLR[166.11].C sp|Q01081|U2AF1_HUMAN 1 1382.6414 0.98 111840 5867 2 1382.639993 692.328 Splicing factor U2AF 35 kDa subunit OS=Homo sapiens OX=9606 GN=U2AF1 PE=1 SV=3 5.84 1550.1 - 4.76E+06 - - - -1.0104 - 3.008 0.572 - 817.5 1 2 0 -0.0014 13 0 0 0 5.11E+07 5.23E+07 - - - 6.0918 0.9865 221125_WJC_METTL3_EV_vs_WT_F08.05868.05868.3 2.54E-05 Dec-40 F.C[160.03]DYGTK[136.11]EEC[160.03]MK[136.11].A "sp|Q86U44|MTA70_HUMAN,tr|H0YFV6|H0YFV6_HUMAN" 2 1435.5753 0.04 111841 5868 3 1435.578693 479.5324 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 4.68 1550.1 - 4.11E+06 - - - 2.3823 - 2.41 0.627 - 205.4 1 1 1 0.0034 11 0 0 0 3.85E+06 8.77E+07 - - - 8.0283 0.9997 221125_WJC_METTL3_EV_vs_WT_F08.05869.05869.2 1.29E-05 16/22 R.R[166.11]YPSSISSSPQK[136.11].D "sp|Q14157|UBP2L_HUMAN,tr|F8W726|F8W726_HUMAN" 2 1353.7007 2.21 111842 5869 2 1353.697244 677.8577 Ubiquitin-associated protein 2-like OS=Homo sapiens OX=9606 GN=UBAP2L PE=1 SV=2 9.99 1550.2 - 2.30E+06 - - - -2.5892 - 2.491 0.504 - 630.6 1 2 0 -0.0035 12 0 0 0 8.27E+07 3.74E+07 - - - 5.1639 1 221125_WJC_METTL3_EV_vs_WT_F08.05871.05871.2 3.41E-07 13/24 K.ANGTSALTAQNGK.A "sp|Q14978|NOLC1_HUMAN,tr|A0A0A0MRM9|A0A0A0MRM9_HUMAN" 2 1231.6157 2.34 111844 5871 2 1231.613013 616.8151 Nucleolar and coiled-body phosphoprotein 1 OS=Homo sapiens OX=9606 GN=NOLC1 PE=1 SV=2 8.8 1550.5 - 1.83E+06 - - - -2.1646 - 2.894 0.569 - 794.9 1 2 0 -0.0027 13 0 0 0 2.63E+07 1.13E+07 - - - 5.9701 1 221125_WJC_METTL3_EV_vs_WT_F08.05873.05873.2 5.22E-07 15/22 K.SYSVGASGSSSR.K "sp|Q8N684|CPSF7_HUMAN,tr|F5H669|F5H669_HUMAN" 2 1143.5156 1.07 111846 5873 2 1143.513481 572.7651 Cleavage and polyadenylation specificity factor subunit 7 OS=Homo sapiens OX=9606 GN=CPSF7 PE=1 SV=1 8.46 1550.8 - 1.28E+06 - - - -1.8793 - 2.441 0.618 - 692.7 1 2 0 -0.0021 12 0 0 0 2.84E+07 2.66E+07 - - - 5.9529 0.9995 221125_WJC_METTL3_EV_vs_WT_F08.05879.05879.3 0.00298 14/48 R.TK[136.11]TPGPGAQSALR[166.11].A "sp|P62263|RS14_HUMAN,tr|A0A2R8Y811|A0A2R8Y811_HUMAN,tr|E5RH77|E5RH77_HUMAN" 3 1300.7218 1.3 111850 5879 3 1300.719264 434.5812 40S ribosomal protein S14 OS=Homo sapiens OX=9606 GN=RPS14 PE=1 SV=3 11 1551.6 - 1.37E+08 - - - -1.9643 - 2.694 0.404 - 335 1 2 1 -0.0026 13 0 0 0 1.64E+09 1.25E+09 - - - 5.7305 0.9998 221125_WJC_METTL3_EV_vs_WT_F08.05880.05880.2 0.00249 18-Sep K.SQESNVSIQK[136.11].E "sp|Q15643|TRIPB_HUMAN,tr|H0YJ97|H0YJ97_HUMAN" 2 1126.571 1.15 111851 5880 2 1126.569802 564.2928 Thyroid receptor-interacting protein 11 OS=Homo sapiens OX=9606 GN=TRIP11 PE=1 SV=3 5.72 1551.6 - 3.15E+07 - - - -1.0341 - 2.061 0.426 - 333.1 1 2 0 -0.0012 10 0 0 0 2.21E+08 1.92E+08 - - - 4.2057 0.9949 221125_WJC_METTL3_EV_vs_WT_F08.05882.05882.2 0.0425 24-Dec R.TK[136.11]TPGPGAQSALR[166.11].A "sp|P62263|RS14_HUMAN,tr|A0A2R8Y811|A0A2R8Y811_HUMAN,tr|E5RH77|E5RH77_HUMAN" 3 1300.7218 1.29 111853 5882 2 1300.720128 651.3682 40S ribosomal protein S14 OS=Homo sapiens OX=9606 GN=RPS14 PE=1 SV=3 11 1551.7 - 1.39E+07 - - - -1.3 - 2.077 0.344 - 392.8 1 2 1 -0.0017 13 0 0 0 1.97E+08 1.53E+08 - - - 3.4572 1 221125_WJC_METTL3_EV_vs_WT_F08.05883.05883.3 8.13E-06 Nov-48 K.AAMDNSEIAGEK[136.11]K[136.11].S "sp|Q16891|MIC60_HUMAN,tr|B9A067|B9A067_HUMAN,tr|C9J406|C9J406_HUMAN,tr|H7C463|H7C463_HUMAN" 4 1378.6733 1.44 111854 5883 3 1378.672112 460.5651 MICOS complex subunit MIC60 OS=Homo sapiens OX=9606 GN=IMMT PE=1 SV=1 4.68 1551.7 - 1.13E+07 - - - -0.8835 - 2.21 0.598 - 146.4 1 2 0 -0.0012 13 0 0 0 1.30E+08 9.03E+07 - - - 7.3568 0.9999 221125_WJC_METTL3_EV_vs_WT_F08.05884.05884.2 1.07E-05 13/22 K.SYSVGASGSSSR[166.11].K "sp|Q8N684|CPSF7_HUMAN,tr|F5H669|F5H669_HUMAN" 2 1153.5239 1.05 111855 5884 2 1153.522551 577.7692 Cleavage and polyadenylation specificity factor subunit 7 OS=Homo sapiens OX=9606 GN=CPSF7 PE=1 SV=1 8.46 1551.8 - 4.11E+06 - - - -1.1695 - 2.069 0.609 - 518.9 1 2 0 -0.0013 12 0 0 0 2.84E+07 2.71E+07 - - - 5.4517 0.9999 221125_WJC_METTL3_EV_vs_WT_F08.05886.05886.2 6.12E-09 14/20 K.NSDADFQNNEK[136.11].F "sp|Q96MF7|NSE2_HUMAN,tr|E5RHW9|E5RHW9_HUMAN,tr|E5RIM1|E5RIM1_HUMAN,tr|A0A087WTZ8|A0A087WTZ8_HUMAN,tr|E5RFJ1|E5RFJ1_HUMAN" 5 1288.5411 1.46 111857 5886 2 1288.539757 645.2778 E3 SUMO-protein ligase NSE2 OS=Homo sapiens OX=9606 GN=NSMCE2 PE=1 SV=2 4.03 1551.8 - 3.61E+06 - - - -1.0601 - 2.758 0.479 - 548.5 1 2 0 -0.0014 11 0 0 0 3.57E+07 2.44E+07 - - - 5.3229 0.9989 221125_WJC_METTL3_EV_vs_WT_F08.05890.05890.2 1.25E-11 13/24 K.AAMDNSEIAGEKK.S "sp|Q16891|MIC60_HUMAN,tr|B9A067|B9A067_HUMAN,tr|C9J406|C9J406_HUMAN,tr|H7C463|H7C463_HUMAN" 4 1362.6449 2.05 111861 5890 2 1362.640496 682.3297 MICOS complex subunit MIC60 OS=Homo sapiens OX=9606 GN=IMMT PE=1 SV=1 4.68 1552.2 - 2.36E+06 - - - -3.254 - 2.826 0.324 - 575.4 1 2 0 -0.0044 13 0 0 0 1.59E+07 7.76E+06 - - - 4.0989 1 221125_WJC_METTL3_EV_vs_WT_F08.05892.05892.3 1.12E-05 16/52 K.AVTEQGHELSNEER[166.11].N "sp|P31946|1433B_HUMAN,tr|Q4VY19|Q4VY19_HUMAN,tr|A0A0J9YWZ2|A0A0J9YWZ2_HUMAN,tr|Q4VY20|Q4VY20_HUMAN,tr|A0A0J9YWE8|A0A0J9YWE8_HUMAN" 5 1607.7415 1.18 111863 5892 3 1607.739164 536.9211 14-3-3 protein beta\alpha OS=Homo sapiens OX=9606 GN=YWHAB PE=1 SV=3 4.48 1552.3 - 1.97E+06 - - - -1.4517 - 3.048 0.568 - 321 1 2 0 -0.0023 14 0 0 0 7.19E+07 6.10E+07 - - - 7.8338 1 221125_WJC_METTL3_EV_vs_WT_F08.05893.05893.2 1.29E-06 14/24 K.ANGTSALTAQNGK[136.11].A "sp|Q14978|NOLC1_HUMAN,tr|A0A0A0MRM9|A0A0A0MRM9_HUMAN" 2 1239.6299 2.34 111864 5893 2 1239.627377 620.8222 Nucleolar and coiled-body phosphoprotein 1 OS=Homo sapiens OX=9606 GN=NOLC1 PE=1 SV=2 8.8 1552.5 - 1.73E+06 - - - -2.0183 - 2.877 0.569 - 986.7 1 2 0 -0.0025 13 0 0 0 2.63E+07 1.13E+07 - - - 5.955 0.7961 221125_WJC_METTL3_EV_vs_WT_F08.05894.05894.2 0.000119 13/20 F.C[160.03]DYGTK[136.11]EEC[160.03]MK[136.11].A "sp|Q86U44|MTA70_HUMAN,tr|H0YFV6|H0YFV6_HUMAN" 2 1435.5753 0.001 111865 5894 2 1435.570977 718.7949 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 4.68 1552.6 - 1.34E+06 - - - -2.9925 - 2.229 0.594 - 483.9 1 1 1 -0.0043 11 0 0 0 0.00E+00 7.49E+06 - - - 5.5953 0.8421 221125_WJC_METTL3_EV_vs_WT_F08.05896.05896.2 1.37 18-Aug F.K[136.11]IEDSAQVAR[166.11].L sp|O95238|SPDEF_HUMAN 1 1133.616 2.97 111867 5896 2 1133.616928 567.8153 SAM pointed domain-containing Ets transcription factor OS=Homo sapiens OX=9606 GN=SPDEF PE=1 SV=1 6.07 1552.8 - 1.04E+06 - - - 0.8566 - 1.673 0.154 - 179.1 1 1 0 0.001 10 0 0 0 1.53E+07 5.15E+06 - - - 1.6146 0.9982 221125_WJC_METTL3_EV_vs_WT_F08.05902.05902.3 0.0727 Sep-40 K.SSPQAAVPYK[136.11]K[136.11].D "sp|Q9H2P0|ADNP_HUMAN,tr|A0A2R8Y6X0|A0A2R8Y6X0_HUMAN,tr|A0A669KBJ7|A0A669KBJ7_HUMAN" 3 1190.663 0.9 111871 5902 3 1190.661083 397.895 Activity-dependent neuroprotector homeobox protein OS=Homo sapiens OX=9606 GN=ADNP PE=1 SV=1 9.7 1553.5 - 3.78E+06 - - - -1.6293 - 1.887 0.251 - 131 1 2 0 -0.0019 11 0 0 0 2.22E+07 2.48E+07 - - - 3.1418 0.9999 221125_WJC_METTL3_EV_vs_WT_F08.05903.05903.3 8.68E-05 Dec-40 K.KESDLNGAQIK.L "sp|P20700|LMNB1_HUMAN,tr|A0A0D9SFY5|A0A0D9SFY5_HUMAN,tr|E9PBF6|E9PBF6_HUMAN,tr|A0A0D9SFE5|A0A0D9SFE5_HUMAN" 4 1201.6303 1.24 111872 5903 3 1201.629536 401.5507 Lamin-B1 OS=Homo sapiens OX=9606 GN=LMNB1 PE=1 SV=2 6.07 1553.5 - 8.11E+06 - - - -0.6075 - 2.009 0.455 - 217.8 1 2 0 -0.0007 11 0 0 0 4.47E+07 3.62E+07 - - - 5.5945 1 221125_WJC_METTL3_EV_vs_WT_F08.05904.05904.2 8.48E-06 18/20 K.KESDLNGAQIK.L "sp|P20700|LMNB1_HUMAN,tr|A0A0D9SFY5|A0A0D9SFY5_HUMAN,tr|E9PBF6|E9PBF6_HUMAN,tr|A0A0D9SFE5|A0A0D9SFE5_HUMAN" 4 1201.6303 1.14 111873 5904 2 1201.630081 601.8224 Lamin-B1 OS=Homo sapiens OX=9606 GN=LMNB1 PE=1 SV=2 6.07 1553.6 - 3.73E+06 - - - -0.154 - 3.588 0.518 - 1132.8 1 2 0 -0.0002 11 0 0 0 2.03E+07 1.78E+07 - - - 6.3231 1 221125_WJC_METTL3_EV_vs_WT_F08.05905.05905.2 0.00057 17/20 K.K[136.11]ESDLNGAQIK[136.11].L "sp|P20700|LMNB1_HUMAN,tr|A0A0D9SFY5|A0A0D9SFY5_HUMAN,tr|E9PBF6|E9PBF6_HUMAN,tr|A0A0D9SFE5|A0A0D9SFE5_HUMAN" 4 1217.6587 1.14 111874 5905 2 1217.657998 609.8366 Lamin-B1 OS=Homo sapiens OX=9606 GN=LMNB1 PE=1 SV=2 6.07 1553.7 - 3.44E+06 - - - -0.5486 - 3.513 0.537 - 930.2 1 2 0 -0.0007 11 0 0 0 2.03E+07 1.78E+07 - - - 6.4061 0.9509 221125_WJC_METTL3_EV_vs_WT_F08.05906.05906.3 0.0378 Oct-40 K.SSPQAAVPYKK.D "sp|Q9H2P0|ADNP_HUMAN,tr|A0A2R8Y6X0|A0A2R8Y6X0_HUMAN,tr|A0A669KBJ7|A0A669KBJ7_HUMAN" 3 1174.6346 0.9 111875 5906 3 1174.633134 392.5522 Activity-dependent neuroprotector homeobox protein OS=Homo sapiens OX=9606 GN=ADNP PE=1 SV=1 9.7 1553.7 - 2.90E+06 - - - -1.2676 - 1.68 0.083 - 143.9 1 2 0 -0.0015 11 0 0 0 2.22E+07 2.48E+07 - - - 0.9388 1 221125_WJC_METTL3_EV_vs_WT_F08.05911.05911.2 2.73E-06 13/24 K.AAMDNSEIAGEK[136.11]K[136.11].S "sp|Q16891|MIC60_HUMAN,tr|B9A067|B9A067_HUMAN,tr|C9J406|C9J406_HUMAN,tr|H7C463|H7C463_HUMAN" 4 1378.6733 2.05 111880 5911 2 1378.670365 690.3439 MICOS complex subunit MIC60 OS=Homo sapiens OX=9606 GN=IMMT PE=1 SV=1 4.68 1554.2 - 1.18E+06 - - - -2.1506 - 2.672 0.605 - 530.1 1 2 0 -0.003 13 0 0 0 1.59E+07 7.76E+06 - - - 6.0311 0.9986 221125_WJC_METTL3_EV_vs_WT_F08.05913.05913.2 1.96E-05 14/20 K.ETSKDTETVLK.T sp|Q9NP61|ARFG3_HUMAN 1 1249.6402 1.41 111882 5913 2 1249.639077 625.8274 ADP-ribosylation factor GTPase-activating protein 3 OS=Homo sapiens OX=9606 GN=ARFGAP3 PE=1 SV=1 4.68 1554.4 - 708228 - - - -0.8682 - 2.462 0.487 - 524.7 1 2 1 -0.0011 11 0 0 0 1.58E+07 1.12E+07 - - - 5.075 0.9998 221125_WJC_METTL3_EV_vs_WT_F08.05914.05914.2 0.000223 20-Aug K.SSPQAAVPYK[136.11]K[136.11].D "sp|Q9H2P0|ADNP_HUMAN,tr|A0A2R8Y6X0|A0A2R8Y6X0_HUMAN,tr|A0A669KBJ7|A0A669KBJ7_HUMAN" 3 1190.663 0.98 111883 5914 2 1190.662262 596.3388 Activity-dependent neuroprotector homeobox protein OS=Homo sapiens OX=9606 GN=ADNP PE=1 SV=1 9.7 1554.6 - 561007 - - - -0.6391 - 1.764 0.458 - 221.2 1 2 0 -0.0008 11 0 0 0 2.64E+06 2.70E+06 - - - 3.959 0.9999 221125_WJC_METTL3_EV_vs_WT_F08.05916.05916.3 7.41E-05 13/44 K.TTGNATVDHLSK.Y sp|Q06587|RING1_HUMAN 1 1242.6204 0.66 111884 5916 3 1242.618586 415.2141 E3 ubiquitin-protein ligase RING1 OS=Homo sapiens OX=9606 GN=RING1 PE=1 SV=2 6.41 1554.8 - 9.89E+06 - - - -1.484 - 2.129 0.422 - 226.9 1 2 0 -0.0018 12 0 0 0 5.80E+07 8.84E+07 - - - 5.3389 0.9769 221125_WJC_METTL3_EV_vs_WT_F08.05920.05920.2 0.00485 18-Oct L.SSVQENIQQK.S "sp|P52732|KIF11_HUMAN,tr|A0A7I2V3A9|A0A7I2V3A9_HUMAN" 2 1159.5833 4.36 111887 5920 2 1159.584637 580.7989 Kinesin-like protein KIF11 OS=Homo sapiens OX=9606 GN=KIF11 PE=1 SV=2 5.72 1555.1 - 2.25E+06 - - - 1.1392 - 2.011 0.362 - 593.6 1 1 0 0.0013 10 0 0 0 5.05E+07 1.16E+07 - - - 3.6644 0.9999 221125_WJC_METTL3_EV_vs_WT_F08.05921.05921.2 4.94E-06 24-Nov K.EQTFSGGTSQDTK.A "sp|Q9Y2W1|TR150_HUMAN,tr|A0A3B3ITZ9|A0A3B3ITZ9_HUMAN" 2 1384.6107 2.45 111888 5921 2 1384.611252 693.3126 Thyroid hormone receptor-associated protein 3 OS=Homo sapiens OX=9606 GN=THRAP3 PE=1 SV=2 4.37 1555.1 - 1.94E+06 - - - 0.4326 - 2.336 0.516 - 384.3 1 2 0 0.0006 13 0 0 0 3.22E+09 1.31E+09 - - - 5.0295 0.9995 221125_WJC_METTL3_EV_vs_WT_F08.05922.05922.3 0.0148 Jul-40 K.VYLC[160.03]NQDENHK.H "sp|Q02487|DSC2_HUMAN,tr|A0A3B3ISU0|A0A3B3ISU0_HUMAN" 2 1418.6249 1.06 111889 5922 3 1418.624724 473.8822 Desmocollin-2 OS=Homo sapiens OX=9606 GN=DSC2 PE=1 SV=1 5.32 1555.2 - 1.89E+06 - - - -0.098 - 1.499 0.366 - 43.8 1 2 0 -0.0001 11 0 0 0 8.56E+06 8.10E+06 - - - 3.7705 1 221125_WJC_METTL3_EV_vs_WT_F08.05923.05923.2 1.37E-06 19/28 K.ATDLGGTSQAGTSQR[166.11].F "sp|Q7Z2W4|ZCCHV_HUMAN,tr|C9J6P4|C9J6P4_HUMAN,tr|A0A7P0T8C6|A0A7P0T8C6_HUMAN" 3 1458.6938 0.92 111890 5923 2 1458.693191 730.3542 Zinc finger CCCH-type antiviral protein 1 OS=Homo sapiens OX=9606 GN=ZC3HAV1 PE=1 SV=3 5.88 1555.3 - 1.77E+06 - - - -0.4305 - 3.743 0.632 - 1200.1 1 2 0 -0.0006 15 0 0 0 2.67E+07 2.91E+07 - - - 6.9538 0.998 221125_WJC_METTL3_EV_vs_WT_F08.05926.05926.2 1.35E-05 13/20 K.ETSK[136.11]DTETVLK[136.11].T sp|Q9NP61|ARFG3_HUMAN 1 1265.6686 1.41 111893 5926 2 1265.668513 633.8416 ADP-ribosylation factor GTPase-activating protein 3 OS=Homo sapiens OX=9606 GN=ARFGAP3 PE=1 SV=1 4.68 1555.6 - 1.37E+06 - - - -0.0387 - 2.127 0.428 - 413.2 1 2 1 0 11 0 0 0 1.58E+07 1.12E+07 - - - 4.2439 1 221125_WJC_METTL3_EV_vs_WT_F08.05927.05927.2 2.15E-10 20/28 K.ATDLGGTSQAGTSQR.F "sp|Q7Z2W4|ZCCHV_HUMAN,tr|C9J6P4|C9J6P4_HUMAN,tr|A0A7P0T8C6|A0A7P0T8C6_HUMAN" 3 1448.6855 0.92 111894 5927 2 1448.683075 725.3501 Zinc finger CCCH-type antiviral protein 1 OS=Homo sapiens OX=9606 GN=ZC3HAV1 PE=1 SV=3 5.88 1555.8 - 1.24E+06 - - - -1.7078 - 3.67 0.652 - 1325.6 1 2 0 -0.0025 15 0 0 0 2.67E+07 2.91E+07 - - - 7.0525 1 221125_WJC_METTL3_EV_vs_WT_F08.05929.05929.2 3.81E-09 16/26 K.AVTEQGHELSNEER.N "sp|P31946|1433B_HUMAN,tr|Q4VY19|Q4VY19_HUMAN,tr|A0A0J9YWZ2|A0A0J9YWZ2_HUMAN,tr|Q4VY20|Q4VY20_HUMAN,tr|A0A0J9YWE8|A0A0J9YWE8_HUMAN" 5 1597.7332 1.14 111896 5929 2 1597.732608 799.8739 14-3-3 protein beta\alpha OS=Homo sapiens OX=9606 GN=YWHAB PE=1 SV=3 4.48 1556 - 744048 - - - -0.388 - 3.084 0.594 - 765.8 1 2 0 -0.0006 14 0 0 0 5.61E+06 4.94E+06 - - - 6.2543 1 221125_WJC_METTL3_EV_vs_WT_F08.05930.05930.2 6.48E-05 16/26 K.AVTEQGHELSNEER[166.11].N "sp|P31946|1433B_HUMAN,tr|Q4VY19|Q4VY19_HUMAN,tr|A0A0J9YWZ2|A0A0J9YWZ2_HUMAN,tr|Q4VY20|Q4VY20_HUMAN,tr|A0A0J9YWE8|A0A0J9YWE8_HUMAN" 5 1607.7415 1.14 111897 5930 2 1607.742396 804.878 14-3-3 protein beta\alpha OS=Homo sapiens OX=9606 GN=YWHAB PE=1 SV=3 4.48 1556.1 - 714351 - - - 0.5585 - 2.892 0.574 - 497.6 1 2 0 0.0009 14 0 0 0 5.61E+06 4.94E+06 - - - 5.9452 0.9995 221125_WJC_METTL3_EV_vs_WT_F08.05931.05931.2 0.000421 28-Jul K.KPEAGEEPPTQGAEG.- "sp|Q9P1Y6|PHRF1_HUMAN,tr|B7ZM65|B7ZM65_HUMAN,tr|A0A0J9YYB5|A0A0J9YYB5_HUMAN,tr|A0A0J9YWD5|A0A0J9YWD5_HUMAN,tr|F8WEF5|F8WEF5_HUMAN,tr|E9PJ24|E9PJ24_HUMAN" 6 1495.6791 1.99 111898 5931 2 1495.677518 748.8468 PHD and RING finger domain-containing protein 1 OS=Homo sapiens OX=9606 GN=PHRF1 PE=1 SV=3 4.09 1556.3 - 358370 - - - -1.0356 - 1.547 0.43 - 69.9 1 2 0 -0.0015 15 0 0 0 1.71E+06 8.58E+05 - - - 3.2892 1 221125_WJC_METTL3_EV_vs_WT_F08.05936.05936.2 3.33E-06 24-Nov K.EQTFSGGTSQDTK[136.11].A "sp|Q9Y2W1|TR150_HUMAN,tr|A0A3B3ITZ9|A0A3B3ITZ9_HUMAN" 2 1392.6249 2.45 111901 5936 2 1392.624662 697.3197 Thyroid hormone receptor-associated protein 3 OS=Homo sapiens OX=9606 GN=THRAP3 PE=1 SV=2 4.37 1556.9 - 2.52E+07 - - - -0.1372 - 2.43 0.596 - 430.6 1 2 0 -0.0002 13 0 0 0 3.22E+09 1.31E+09 - - - 5.7218 0.9999 221125_WJC_METTL3_EV_vs_WT_F08.05940.05940.3 4.63E-05 Aug-44 K.GPQNATDSYVHK.Q "sp|O43660|PLRG1_HUMAN,tr|D6RA26|D6RA26_HUMAN,tr|B7Z982|B7Z982_HUMAN" 3 1315.6157 0.98 111905 5940 3 1315.618056 439.5458 Pleiotropic regulator 1 OS=Homo sapiens OX=9606 GN=PLRG1 PE=1 SV=1 6.74 1557.1 - 6.88E+06 - - - 1.8068 - 1.976 0.443 - 89.2 1 2 0 0.0024 12 0 0 0 5.67E+07 5.76E+07 - - - 5.3662 0.9995 221125_WJC_METTL3_EV_vs_WT_F08.05941.05941.3 0.0338 Oct-44 K.VNTLIR[166.11]PDGEK[136.11]K[136.11].A "sp|P62750|RL23A_HUMAN,tr|K7EMA7|K7EMA7_HUMAN,tr|H7BY10|H7BY10_HUMAN,tr|K7ERT8|K7ERT8_HUMAN,tr|A8MUS3|A8MUS3_HUMAN,tr|K7EJV9|K7EJV9_HUMAN" 6 1394.8092 0.65 111906 5941 3 1394.808969 465.9437 60S ribosomal protein L23a OS=Homo sapiens OX=9606 GN=RPL23A PE=1 SV=1 8.56 1557.1 - 4.12E+06 - - - -0.1541 - 1.927 0.316 - 100.4 1 2 0 -0.0002 12 0 0 0 9.50E+07 1.46E+08 - - - 3.8813 0.9998 221125_WJC_METTL3_EV_vs_WT_F08.05942.05942.3 0.0155 Dec-48 K.IENVPTGPNNKPK.L "sp|O43447|PPIH_HUMAN,tr|H0YEL5|H0YEL5_HUMAN,tr|A0A7I2YQS4|A0A7I2YQS4_HUMAN,tr|C9JQD4|C9JQD4_HUMAN" 4 1406.7518 3.32 111907 5942 3 1406.751326 469.9245 Peptidyl-prolyl cis-trans isomerase H OS=Homo sapiens OX=9606 GN=PPIH PE=1 SV=1 8.59 1557.2 - 2.66E+06 - - - -0.3213 - 2.535 0.314 - 204.8 1 2 0 -0.0005 13 0 0 0 8.72E+07 2.63E+07 - - - 4.5627 0.9983 221125_WJC_METTL3_EV_vs_WT_F08.05943.05943.3 0.00463 Sep-48 K.EQTFSGGTSQDTK.A "sp|Q9Y2W1|TR150_HUMAN,tr|A0A3B3ITZ9|A0A3B3ITZ9_HUMAN" 2 1384.6107 1.25 111908 5943 3 1384.614585 462.5442 Thyroid hormone receptor-associated protein 3 OS=Homo sapiens OX=9606 GN=THRAP3 PE=1 SV=2 4.37 1557.2 - 2.46E+06 - - - 2.8398 - 1.682 0.347 - 119.2 1 2 0 0.0039 13 0 0 0 8.48E+07 6.78E+07 - - - 3.8174 1 221125_WJC_METTL3_EV_vs_WT_F08.05953.05953.2 2.39E-07 22-Sep K.GPQNATDSYVHK.Q "sp|O43660|PLRG1_HUMAN,tr|D6RA26|D6RA26_HUMAN,tr|B7Z982|B7Z982_HUMAN" 3 1315.6157 0.84 111918 5953 2 1315.622832 658.8151 Pleiotropic regulator 1 OS=Homo sapiens OX=9606 GN=PLRG1 PE=1 SV=1 6.74 1558.2 - 447360 - - - 5.437 - 2.337 0.605 - 321.9 1 2 0 0.0072 12 0 0 0 3.97E+06 4.73E+06 - - - 5.7408 0.9991 221125_WJC_METTL3_EV_vs_WT_F08.05957.05957.2 5.07E-05 14/22 K.DPESNINSDNEK[136.11].L "sp|Q9H2U1|DHX36_HUMAN,tr|A0A0G2JRP3|A0A0G2JRP3_HUMAN,tr|A0A0G2JQU7|A0A0G2JQU7_HUMAN,tr|E7EWK3|E7EWK3_HUMAN" 4 1368.5885 1.23 111921 5957 2 1368.59382 685.3015 ATP-dependent DNA\RNA helicase DHX36 OS=Homo sapiens OX=9606 GN=DHX36 PE=1 SV=2 3.92 1558.7 - 765448 - - - 3.9113 - 2.206 0.544 - 643.8 1 2 0 0.0054 12 0 0 0 1.01E+07 8.17E+06 - - - 5.139 0.9998 221125_WJC_METTL3_EV_vs_WT_F08.05960.05960.3 0.000525 Dec-44 K.VNTLIRPDGEKK.A "sp|P62750|RL23A_HUMAN,tr|K7EMA7|K7EMA7_HUMAN,tr|H7BY10|H7BY10_HUMAN,tr|K7ERT8|K7ERT8_HUMAN,tr|A8MUS3|A8MUS3_HUMAN,tr|K7EJV9|K7EJV9_HUMAN" 6 1368.7725 0.67 111923 5960 3 1368.768939 457.2648 60S ribosomal protein L23a OS=Homo sapiens OX=9606 GN=RPL23A PE=1 SV=1 8.56 1559 - 6.68E+06 - - - -2.6118 - 2.509 0.385 - 166.6 1 2 0 -0.0036 12 0 0 0 9.77E+07 1.47E+08 - - - 5.3812 0.9892 221125_WJC_METTL3_EV_vs_WT_F08.05963.05963.3 0.128 Oct-32 K.EKQEDIMNR.M "sp|Q99567|NUP88_HUMAN,tr|J3KMX1|J3KMX1_HUMAN" 2 1161.5448 1.72 111926 5963 3 1161.544991 388.1889 Nuclear pore complex protein Nup88 OS=Homo sapiens OX=9606 GN=NUP88 PE=1 SV=2 4.68 1559.1 - 3.89E+06 - - - 0.1455 - 1.518 0.262 - 157.1 1 2 1 0.0002 9 0 0 0 1.54E+07 8.91E+06 - - - 2.7189 0.9999 221125_WJC_METTL3_EV_vs_WT_F08.05967.05967.3 0.000166 Nov-36 R.DAVTYTEHAK[136.11].R sp|P62805|H4_HUMAN 1 1141.5495 0.001 111930 5967 3 1141.549547 381.5238 Histone H4 OS=Homo sapiens OX=9606 GN=H4C1 PE=1 SV=2 5.32 1559.3 - 2.80E+06 - - - 0.0385 - 2.005 0.437 - 206.8 1 2 0 0 10 0 0 0 0.00E+00 2.10E+07 - - - 5.4437 0.9972 221125_WJC_METTL3_EV_vs_WT_F08.05971.05971.3 0.0358 Oct-36 R.NTPYQAPVRR.Q sp|P49790|NU153_HUMAN 1 1200.6364 2.45 111934 5971 3 1200.637074 401.2194 Nuclear pore complex protein Nup153 OS=Homo sapiens OX=9606 GN=NUP153 PE=1 SV=2 10.84 1559.6 - 1.38E+06 - - - 0.5997 - 1.883 0.198 - 146.8 1 2 0 0.0007 10 0 0 0 1.77E+07 7.21E+06 - - - 2.5956 0.9999 221125_WJC_METTL3_EV_vs_WT_F08.05972.05972.2 2.74E-05 18-Nov R.DAVTYTEHAK[136.11].R sp|P62805|H4_HUMAN 1 1141.5495 1.21 111935 5972 2 1141.549251 571.782 Histone H4 OS=Homo sapiens OX=9606 GN=H4C1 PE=1 SV=2 5.32 1559.7 - 1.20E+06 - - - -0.2208 - 2.363 0.492 - 578.8 1 2 0 -0.0003 10 0 0 0 1.27E+07 1.05E+07 - - - 5.0752 0.9975 221125_WJC_METTL3_EV_vs_WT_F08.05974.05974.2 0.2 16-Jul R.DK[136.11]PTNNFPK[136.11].N sp|O60825|F262_HUMAN 1 1075.5633 3.9 111937 5974 2 1075.562441 538.7889 "6-phosphofructo-2-kinase\fructose-2,6-bisphosphatase 2 OS=Homo sapiens OX=9606 GN=PFKFB2 PE=1 SV=2" 8.59 1560 - 745967 - - - -0.807 - 1.44 0.217 - 111.6 1 2 0 -0.0009 9 0 0 0 2.41E+07 6.19E+06 - - - 1.6984 0.8125 221125_WJC_METTL3_EV_vs_WT_F08.05978.05978.2 5.55 16-May R.EHIQLNESK[136.11].L sp|P35573|GDE_HUMAN 1 1104.5655 0.87 111941 5978 2 1104.564554 553.29 Glycogen debranching enzyme OS=Homo sapiens OX=9606 GN=AGL PE=1 SV=3 5.4 1560.5 - 377420 - - - -0.8447 - 1.009 0.005 - 67.6 7 2 0 -0.0009 9 0 0 0 2.02E+06 2.33E+06 - - - -1.2739 0.9996 221125_WJC_METTL3_EV_vs_WT_F08.05982.05982.3 0.00012 Dec-40 K.LLEQYK[136.11]EESK[136.11]K[136.11].A "sp|Q00839|HNRPU_HUMAN,tr|A0A1W2PQL0|A0A1W2PQL0_HUMAN,tr|A0A1W2PPL4|A0A1W2PPL4_HUMAN,tr|Q5RI18|Q5RI18_HUMAN,tr|A0A1W2PP35|A0A1W2PP35_HUMAN,tr|A0A1W2PPS1|A0A1W2PPS1_HUMAN,tr|A0A1W2PPH7|A0A1W2PPH7_HUMAN,tr|A0A1W2PQD4|A0A1W2PQD4_HUMAN,tr|A0A1W2PP34|A0A1W2PP34_HUMAN,tr|A0A1X7SBS1|A0A1X7SBS1_HUMAN" 10 1417.7879 1.05 111943 5982 3 1417.785697 473.6032 Heterogeneous nuclear ribonucleoprotein U OS=Homo sapiens OX=9606 GN=HNRNPU PE=1 SV=6 6.23 1560.9 - 1.46E+07 - - - -1.551 - 2.333 0.412 - 205.4 1 2 1 -0.0022 11 0 0 0 5.44E+09 5.20E+09 - - - 5.5394 0.9999 221125_WJC_METTL3_EV_vs_WT_F08.05983.05983.3 0.00545 Dec-36 R.KESEFDDEPK.F "sp|Q9Y2W1|TR150_HUMAN,tr|A0A3B3ITZ9|A0A3B3ITZ9_HUMAN" 2 1222.5354 2.86 111944 5983 3 1222.532776 408.5191 Thyroid hormone receptor-associated protein 3 OS=Homo sapiens OX=9606 GN=THRAP3 PE=1 SV=2 4.18 1561 - 3.90E+06 - - - -2.1161 - 1.995 0.448 - 194.3 1 2 0 -0.0026 10 0 0 0 1.78E+09 6.23E+08 - - - 5.551 0.9997 221125_WJC_METTL3_EV_vs_WT_F08.05984.05984.2 0.000113 18-Nov R.DAVTYTEHAK.R sp|P62805|H4_HUMAN 1 1133.5353 1.21 111945 5984 2 1133.534342 567.7749 Histone H4 OS=Homo sapiens OX=9606 GN=H4C1 PE=1 SV=2 5.32 1561.1 - 2.62E+06 - - - -0.8478 - 2.394 0.322 - 555.9 1 2 0 -0.001 10 0 0 0 1.27E+07 1.05E+07 - - - 3.8557 0.9962 221125_WJC_METTL3_EV_vs_WT_F08.05985.05985.2 0.00688 24-Oct K.IENVPTGPNNKPK.L "sp|O43447|PPIH_HUMAN,tr|H0YEL5|H0YEL5_HUMAN,tr|A0A7I2YQS4|A0A7I2YQS4_HUMAN,tr|C9JQD4|C9JQD4_HUMAN" 4 1406.7518 2.37 111946 5985 2 1406.746882 704.3832 Peptidyl-prolyl cis-trans isomerase H OS=Homo sapiens OX=9606 GN=PPIH PE=1 SV=1 8.59 1561.2 - 1.60E+06 - - - -3.4804 - 1.674 0.335 - 239 1 2 0 -0.0049 13 0 0 0 9.28E+06 3.92E+06 - - - 2.8361 0.9998 221125_WJC_METTL3_EV_vs_WT_F08.05988.05988.2 1.94E-06 14/28 R.TTASEPVEQSEATSK[136.11].D sp|Q15007|FL2D_HUMAN 1 1571.7406 0.8 111949 5988 2 1571.737706 786.8776 Pre-mRNA-splicing regulator WTAP OS=Homo sapiens OX=9606 GN=WTAP PE=1 SV=2 4.25 1561.6 - 974070 - - - -1.8483 - 2.574 0.576 - 426.3 1 2 0 -0.0029 15 0 0 0 2.58E+07 3.23E+07 - - - 5.6189 1 221125_WJC_METTL3_EV_vs_WT_F08.05989.05989.2 2.67E-07 18/20 K.LLEQYK[136.11]EESK[136.11]K[136.11].A "sp|Q00839|HNRPU_HUMAN,tr|A0A1W2PQL0|A0A1W2PQL0_HUMAN,tr|A0A1W2PPL4|A0A1W2PPL4_HUMAN,tr|Q5RI18|Q5RI18_HUMAN,tr|A0A1W2PP35|A0A1W2PP35_HUMAN,tr|A0A1W2PPS1|A0A1W2PPS1_HUMAN,tr|A0A1W2PPH7|A0A1W2PPH7_HUMAN,tr|A0A1W2PQD4|A0A1W2PQD4_HUMAN,tr|A0A1W2PP34|A0A1W2PP34_HUMAN,tr|A0A1X7SBS1|A0A1X7SBS1_HUMAN" 10 1417.7879 1.07 111950 5989 2 1417.782 709.9012 Heterogeneous nuclear ribonucleoprotein U OS=Homo sapiens OX=9606 GN=HNRNPU PE=1 SV=6 6.23 1561.7 - 893034 - - - -4.1586 - 3.247 0.509 - 1154.2 1 2 1 -0.0059 11 0 0 0 2.69E+08 2.52E+08 - - - 5.9847 0.999 221125_WJC_METTL3_EV_vs_WT_F08.05992.05992.3 0.000205 13/36 R.TKTEISEMNR.N sp|P05787|K2C8_HUMAN 1 1207.5867 1.54 111952 5992 3 1207.583465 403.5362 "Keratin, type II cytoskeletal 8 OS=Homo sapiens OX=9606 GN=KRT8 PE=1 SV=7" 5.81 1562.1 - 612914 - - - -2.6681 - 2.183 0.415 - 300.4 1 2 1 -0.0032 10 0 0 0 3.60E+07 2.34E+07 - - - 5.4459 0.8222 221125_WJC_METTL3_EV_vs_WT_F08.05993.05993.2 0.00729 16-Oct T.LIR[166.11]PDGEK[136.11]K[136.11].A "sp|P62750|RL23A_HUMAN,tr|K7EMA7|K7EMA7_HUMAN,tr|H7BY10|H7BY10_HUMAN,tr|K7ERT8|K7ERT8_HUMAN,tr|A8MUS3|A8MUS3_HUMAN,tr|K7EJV9|K7EJV9_HUMAN" 6 1080.6502 0.58 111953 5993 2 1080.646864 541.3324 60S ribosomal protein L23a OS=Homo sapiens OX=9606 GN=RPL23A PE=1 SV=1 8.59 1562.2 - 567151 - - - -3.0537 - 1.984 0.214 - 302.2 1 1 0 -0.0033 9 0 0 0 2.20E+06 3.78E+06 - - - 2.6026 0.997 221125_WJC_METTL3_EV_vs_WT_F08.05996.05996.3 0.314 Sep-32 R.RDHFEEAMR.F "sp|P55072|TERA_HUMAN,tr|A0A7P0T8Q5|A0A7P0T8Q5_HUMAN,tr|C9JUP7|C9JUP7_HUMAN,tr|A0A7P0TAW3|A0A7P0TAW3_HUMAN,tr|A0A7I2V540|A0A7I2V540_HUMAN,tr|A0A7P0T8A3|A0A7P0T8A3_HUMAN,tr|A0A7P0TA22|A0A7P0TA22_HUMAN" 7 1189.5298 0.76 111956 5996 3 1189.528495 397.5172 Transitional endoplasmic reticulum ATPase OS=Homo sapiens OX=9606 GN=VCP PE=1 SV=4 5.45 1562.6 - 500439 - - - -1.1307 - 1.744 0.214 - 111.2 1 2 0 -0.0013 9 0 0 0 2.72E+06 3.56E+06 - - - 2.6017 0.9938 221125_WJC_METTL3_EV_vs_WT_F08.05999.05999.3 0.141 Oct-40 K.LLEQYKEESKK.A "sp|Q00839|HNRPU_HUMAN,tr|A0A1W2PQL0|A0A1W2PQL0_HUMAN,tr|A0A1W2PPL4|A0A1W2PPL4_HUMAN,tr|Q5RI18|Q5RI18_HUMAN,tr|A0A1W2PP35|A0A1W2PP35_HUMAN,tr|A0A1W2PPS1|A0A1W2PPS1_HUMAN,tr|A0A1W2PPH7|A0A1W2PPH7_HUMAN,tr|A0A1W2PQD4|A0A1W2PQD4_HUMAN,tr|A0A1W2PP34|A0A1W2PP34_HUMAN,tr|A0A1X7SBS1|A0A1X7SBS1_HUMAN" 10 1393.7453 1.04 111957 5999 3 1393.744836 465.589 Heterogeneous nuclear ribonucleoprotein U OS=Homo sapiens OX=9606 GN=HNRNPU PE=1 SV=6 6.23 1563 - 2.71E+07 - - - -0.33 - 1.897 0.245 - 139 1 2 1 -0.0005 11 0 0 0 5.49E+09 5.26E+09 - - - 3.0903 1 221125_WJC_METTL3_EV_vs_WT_F08.06000.06000.2 1.33E-05 14/18 R.KESEFDDEPK.F "sp|Q9Y2W1|TR150_HUMAN,tr|A0A3B3ITZ9|A0A3B3ITZ9_HUMAN" 2 1222.5354 2.81 111958 6000 2 1222.534696 612.275 Thyroid hormone receptor-associated protein 3 OS=Homo sapiens OX=9606 GN=THRAP3 PE=1 SV=2 4.18 1563 - 2.97E+06 - - - -0.5456 - 2.666 0.606 - 727.5 1 2 0 -0.0007 10 0 0 0 5.99E+08 2.14E+08 - - - 6.2538 1 221125_WJC_METTL3_EV_vs_WT_F08.06001.06001.2 1.65E-08 22-Dec K.TC[160.03]NC[160.03]ETEDYGEK.F "sp|Q00839|HNRPU_HUMAN,tr|A0A1W2PQL0|A0A1W2PQL0_HUMAN,tr|A0A1W2PPL4|A0A1W2PPL4_HUMAN,tr|A0A1W2PQ74|A0A1W2PQ74_HUMAN,tr|Q5RI18|Q5RI18_HUMAN,tr|A0A1W2PP35|A0A1W2PP35_HUMAN,tr|A0A1W2PPS1|A0A1W2PPS1_HUMAN,tr|A0A1W2PRZ7|A0A1W2PRZ7_HUMAN,tr|A0A1W2PPH7|A0A1W2PPH7_HUMAN,tr|A0A1W2PP34|A0A1W2PP34_HUMAN,tr|A0A1X7SBS1|A0A1X7SBS1_HUMAN" 11 1504.5446 1.19 111959 6001 2 1504.543119 753.2796 Heterogeneous nuclear ribonucleoprotein U OS=Homo sapiens OX=9606 GN=HNRNPU PE=1 SV=6 4 1563.1 - 2.50E+06 - - - -1.0003 - 2.459 0.718 - 514.5 1 2 0 -0.0015 12 0 0 0 1.86E+08 1.56E+08 - - - 6.7111 1 221125_WJC_METTL3_EV_vs_WT_F08.06002.06002.2 4.55E-09 22-Dec K.TC[160.03]NC[160.03]ETEDYGEK[136.11].F "sp|Q00839|HNRPU_HUMAN,tr|A0A1W2PQL0|A0A1W2PQL0_HUMAN,tr|A0A1W2PPL4|A0A1W2PPL4_HUMAN,tr|A0A1W2PQ74|A0A1W2PQ74_HUMAN,tr|Q5RI18|Q5RI18_HUMAN,tr|A0A1W2PP35|A0A1W2PP35_HUMAN,tr|A0A1W2PPS1|A0A1W2PPS1_HUMAN,tr|A0A1W2PRZ7|A0A1W2PRZ7_HUMAN,tr|A0A1W2PPH7|A0A1W2PPH7_HUMAN,tr|A0A1W2PP34|A0A1W2PP34_HUMAN,tr|A0A1X7SBS1|A0A1X7SBS1_HUMAN" 11 1512.5588 1.19 111960 6002 2 1512.555895 757.2867 Heterogeneous nuclear ribonucleoprotein U OS=Homo sapiens OX=9606 GN=HNRNPU PE=1 SV=6 4 1563.2 - 2.18E+06 - - - -1.9365 - 2.409 0.788 - 512 1 2 0 -0.0029 12 0 0 0 1.86E+08 1.56E+08 - - - 7.1736 0.7742 221125_WJC_METTL3_EV_vs_WT_F08.06003.06003.3 0.0907 Oct-36 L.LEQYK[136.11]EESK[136.11]K[136.11].A "sp|Q00839|HNRPU_HUMAN,tr|A0A1W2PQL0|A0A1W2PQL0_HUMAN,tr|A0A1W2PPL4|A0A1W2PPL4_HUMAN,tr|Q5RI18|Q5RI18_HUMAN,tr|A0A1W2PP35|A0A1W2PP35_HUMAN,tr|A0A1W2PPS1|A0A1W2PPS1_HUMAN,tr|A0A1W2PPH7|A0A1W2PPH7_HUMAN,tr|A0A1W2PQD4|A0A1W2PQD4_HUMAN,tr|A0A1W2PP34|A0A1W2PP34_HUMAN,tr|A0A1X7SBS1|A0A1X7SBS1_HUMAN" 10 1304.7038 1.04 111961 6003 3 1304.702709 435.9086 Heterogeneous nuclear ribonucleoprotein U OS=Homo sapiens OX=9606 GN=HNRNPU PE=1 SV=6 6.23 1563.3 - 1.93E+06 - - - -0.8607 - 1.754 0.314 - 107.5 1 1 1 -0.0011 10 0 0 0 2.53E+08 2.44E+08 - - - 3.6815 1 221125_WJC_METTL3_EV_vs_WT_F08.06004.06004.2 1.70E-08 16/28 R.TTASEPVEQSEATSK.D sp|Q15007|FL2D_HUMAN 1 1563.7264 0.7 111962 6004 2 1563.725203 782.8705 Pre-mRNA-splicing regulator WTAP OS=Homo sapiens OX=9606 GN=WTAP PE=1 SV=2 4.25 1563.3 - 1.80E+06 - - - -0.7725 - 2.932 0.654 - 648.1 1 2 0 -0.0012 15 0 0 0 1.18E+07 1.68E+07 - - - 6.5157 0.8065 221125_WJC_METTL3_EV_vs_WT_F08.06006.06006.2 1.57 16-Dec L.EQYK[136.11]EESK[136.11]K[136.11].A "sp|Q00839|HNRPU_HUMAN,tr|A0A1W2PQL0|A0A1W2PQL0_HUMAN,tr|A0A1W2PPL4|A0A1W2PPL4_HUMAN,tr|Q5RI18|Q5RI18_HUMAN,tr|A0A1W2PP35|A0A1W2PP35_HUMAN,tr|A0A1W2PPS1|A0A1W2PPS1_HUMAN,tr|A0A1W2PPH7|A0A1W2PPH7_HUMAN,tr|A0A1W2PQD4|A0A1W2PQD4_HUMAN,tr|A0A1W2PP34|A0A1W2PP34_HUMAN,tr|A0A1X7SBS1|A0A1X7SBS1_HUMAN" 10 1191.6198 1.06 111964 6006 2 1191.619097 596.8172 Heterogeneous nuclear ribonucleoprotein U OS=Homo sapiens OX=9606 GN=HNRNPU PE=1 SV=6 6.32 1563.5 - 1.44E+06 - - - -0.5631 - 2.244 0.277 - 430.4 1 1 1 -0.0007 9 0 0 0 1.84E+08 1.73E+08 - - - 3.4251 1 221125_WJC_METTL3_EV_vs_WT_F08.06007.06007.2 4.25E-08 16/26 K.QQVEQSSASQTGIK.Q "sp|Q9H4A3|WNK1_HUMAN,tr|F5GWT4|F5GWT4_HUMAN,tr|A0A6Q8PFM0|A0A6Q8PFM0_HUMAN" 3 1489.7372 1.73 111965 6007 2 1489.734978 745.8759 Serine\threonine-protein kinase WNK1 OS=Homo sapiens OX=9606 GN=WNK1 PE=1 SV=2 6 1563.6 - 1.21E+06 - - - -1.5251 - 2.862 0.594 - 1007.1 1 2 0 -0.0023 14 0 0 0 6.05E+07 3.49E+07 - - - 6.0663 0.9931 221125_WJC_METTL3_EV_vs_WT_F08.06008.06008.2 3.26E-08 13/22 N.TGPNNSNTTFQK.R "sp|Q9NYF8|BCLF1_HUMAN,tr|H0YF14|H0YF14_HUMAN" 2 1307.6106 2.33 111966 6008 2 1307.609575 654.8126 Bcl-2-associated transcription factor 1 OS=Homo sapiens OX=9606 GN=BCLAF1 PE=1 SV=2 8.41 1563.8 - 1.01E+06 - - - -0.7785 - 2.483 0.5 - 740.2 1 1 0 -0.001 12 0 0 0 6.28E+07 2.70E+07 - - - 5.1266 1 221125_WJC_METTL3_EV_vs_WT_F08.06009.06009.2 1.10E-06 13/26 K.QQVEQSSASQTGIK[136.11].Q "sp|Q9H4A3|WNK1_HUMAN,tr|F5GWT4|F5GWT4_HUMAN,tr|A0A6Q8PFM0|A0A6Q8PFM0_HUMAN" 3 1497.7514 1.73 111967 6009 2 1497.7497 749.883 Serine\threonine-protein kinase WNK1 OS=Homo sapiens OX=9606 GN=WNK1 PE=1 SV=2 6 1563.9 - 944122 - - - -1.1684 - 2.537 0.599 - 573.5 1 2 0 -0.0018 14 0 0 0 6.05E+07 3.49E+07 - - - 5.8009 0.9999 221125_WJC_METTL3_EV_vs_WT_F08.06011.06011.3 9.34E-06 14/52 R.IAMENDDGRTEEEK.H "sp|Q8WWM7|ATX2L_HUMAN,tr|H3BSK9|H3BSK9_HUMAN,tr|H3BUF6|H3BUF6_HUMAN" 3 1635.7046 1.79 111969 6011 3 1635.707095 546.2422 Ataxin-2-like protein OS=Homo sapiens OX=9606 GN=ATXN2L PE=1 SV=2 4.08 1564.1 - 677899 - - - 1.507 - 3.27 0.585 - 306.2 1 2 1 0.0025 14 0 0 0 7.27E+07 4.07E+07 - - - 8.2101 0.9824 221125_WJC_METTL3_EV_vs_WT_F08.06015.06015.2 0.0596 18-Nov N.TLIR[166.11]PDGEK[136.11]K[136.11].A "sp|P62750|RL23A_HUMAN,tr|K7EMA7|K7EMA7_HUMAN,tr|H7BY10|H7BY10_HUMAN,tr|K7ERT8|K7ERT8_HUMAN,tr|A8MUS3|A8MUS3_HUMAN,tr|K7EJV9|K7EJV9_HUMAN" 6 1181.6978 0.48 111973 6015 2 1181.697169 591.8562 60S ribosomal protein L23a OS=Homo sapiens OX=9606 GN=RPL23A PE=1 SV=1 8.26 1564.6 - 333163 - - - -0.5695 - 2.138 0.334 - 332.1 1 1 0 -0.0007 10 0 0 0 2.04E+06 4.25E+06 - - - 3.6287 0.9999 221125_WJC_METTL3_EV_vs_WT_F08.06017.06017.3 0.00126 Sep-36 R.K[136.11]ESEFDDEPK[136.11].F "sp|Q9Y2W1|TR150_HUMAN,tr|A0A3B3ITZ9|A0A3B3ITZ9_HUMAN" 2 1238.5638 2.85 111974 6017 3 1238.562205 413.8619 Thyroid hormone receptor-associated protein 3 OS=Homo sapiens OX=9606 GN=THRAP3 PE=1 SV=2 4.18 1564.8 - 4.83E+06 - - - -1.2579 - 1.686 0.45 - 113.9 1 2 0 -0.0016 10 0 0 0 1.80E+09 6.31E+08 - - - 5.0821 0.9997 221125_WJC_METTL3_EV_vs_WT_F08.06021.06021.2 1.64E-05 20-Aug R.SGTHSQSLPDS.- sp|Q13503|MED21_HUMAN 1 1114.4891 - 111977 6021 2 1114.488738 558.2518 Mediator of RNA polymerase II transcription subunit 21 OS=Homo sapiens OX=9606 GN=MED21 PE=1 SV=1 5.06 1565.2 - 1.49E+06 - - - -0.3078 - 1.513 0.449 - 195.4 1 2 0 -0.0003 11 0 0 0 - - - - - 3.4774 1 221125_WJC_METTL3_EV_vs_WT_F08.06022.06022.2 0.00012 16/18 R.K[136.11]ESEFDDEPK[136.11].F "sp|Q9Y2W1|TR150_HUMAN,tr|A0A3B3ITZ9|A0A3B3ITZ9_HUMAN" 2 1238.5638 2.81 111978 6022 2 1238.564107 620.2892 Thyroid hormone receptor-associated protein 3 OS=Homo sapiens OX=9606 GN=THRAP3 PE=1 SV=2 4.18 1565.3 - 994528 - - - 0.2777 - 2.771 0.592 - 913.3 1 2 0 0.0003 10 0 0 0 6.07E+08 2.16E+08 - - - 6.2583 0.8901 221125_WJC_METTL3_EV_vs_WT_F08.06026.06026.2 0.000802 14/18 L.LEQYKEESKK.A "sp|Q00839|HNRPU_HUMAN,tr|A0A1W2PQL0|A0A1W2PQL0_HUMAN,tr|A0A1W2PPL4|A0A1W2PPL4_HUMAN,tr|Q5RI18|Q5RI18_HUMAN,tr|A0A1W2PP35|A0A1W2PP35_HUMAN,tr|A0A1W2PPS1|A0A1W2PPS1_HUMAN,tr|A0A1W2PPH7|A0A1W2PPH7_HUMAN,tr|A0A1W2PQD4|A0A1W2PQD4_HUMAN,tr|A0A1W2PP34|A0A1W2PP34_HUMAN,tr|A0A1X7SBS1|A0A1X7SBS1_HUMAN" 10 1280.6612 1.16 111982 6026 2 1280.662414 641.3379 Heterogeneous nuclear ribonucleoprotein U OS=Homo sapiens OX=9606 GN=HNRNPU PE=1 SV=6 6.23 1565.8 - 678581 - - - 0.923 - 2.586 0.389 - 680.7 1 1 1 0.0012 10 0 0 0 9.01E+07 7.77E+07 - - - 4.5658 0.8987 221125_WJC_METTL3_EV_vs_WT_F08.06027.06027.2 0.262 18-Aug R.TKTEISEMNR.N sp|P05787|K2C8_HUMAN 1 1207.5867 1.39 111983 6027 2 1207.584694 604.8006 "Keratin, type II cytoskeletal 8 OS=Homo sapiens OX=9606 GN=KRT8 PE=1 SV=7" 5.81 1566 - 590453 - - - -1.6504 - 1.292 0.167 - 160.4 1 2 1 -0.002 10 0 0 0 4.99E+06 3.59E+06 - - - 0.9889 0.9999 221125_WJC_METTL3_EV_vs_WT_F08.06028.06028.3 0.000755 14/52 K.QQVEQSSASQTGIK[136.11].Q "sp|Q9H4A3|WNK1_HUMAN,tr|F5GWT4|F5GWT4_HUMAN,tr|A0A6Q8PFM0|A0A6Q8PFM0_HUMAN" 3 1497.7514 4.92 111984 6028 3 1497.748803 500.2578 Serine\threonine-protein kinase WNK1 OS=Homo sapiens OX=9606 GN=WNK1 PE=1 SV=2 6 1566.1 - 521635 - - - -1.7673 - 2.224 0.445 - 319.8 1 2 0 -0.0026 14 0 0 0 3.37E+07 6.85E+06 - - - 5.6248 0.9994 221125_WJC_METTL3_EV_vs_WT_F08.06029.06029.3 0.0329 Sep-36 R.R[166.11]DFAPPGQQK[136.11].R sp|Q9BVC6|TM109_HUMAN 1 1160.6057 1.03 111985 6029 3 1160.604595 387.8759 Transmembrane protein 109 OS=Homo sapiens OX=9606 GN=TMEM109 PE=1 SV=1 8.75 1566.2 - 445260 - - - -0.9745 - 2.07 0.275 - 154.6 1 2 0 -0.0011 10 0 0 0 8.83E+07 8.54E+07 - - - 3.7304 0.9994 221125_WJC_METTL3_EV_vs_WT_F08.06031.06031.3 0.00169 14/36 R.RDFAPPGQQK.R sp|Q9BVC6|TM109_HUMAN 1 1142.5833 1.04 111987 6031 3 1142.587621 381.8684 Transmembrane protein 109 OS=Homo sapiens OX=9606 GN=TMEM109 PE=1 SV=1 8.75 1566.5 - 406829 - - - 3.8203 - 2.299 0.391 - 317.2 1 2 0 0.0044 10 0 0 0 8.83E+07 8.52E+07 - - - 5.3292 0.9984 221125_WJC_METTL3_EV_vs_WT_F08.06038.06038.2 0.00278 14/20 K.LLEQYKEESKK.A "sp|Q00839|HNRPU_HUMAN,tr|A0A1W2PQL0|A0A1W2PQL0_HUMAN,tr|A0A1W2PPL4|A0A1W2PPL4_HUMAN,tr|Q5RI18|Q5RI18_HUMAN,tr|A0A1W2PP35|A0A1W2PP35_HUMAN,tr|A0A1W2PPS1|A0A1W2PPS1_HUMAN,tr|A0A1W2PPH7|A0A1W2PPH7_HUMAN,tr|A0A1W2PQD4|A0A1W2PQD4_HUMAN,tr|A0A1W2PP34|A0A1W2PP34_HUMAN,tr|A0A1X7SBS1|A0A1X7SBS1_HUMAN" 10 1393.7453 1.07 111993 6038 2 1393.744186 697.8799 Heterogeneous nuclear ribonucleoprotein U OS=Homo sapiens OX=9606 GN=HNRNPU PE=1 SV=6 6.23 1567.2 - 3.62E+06 - - - -0.7964 - 2.36 0.462 - 606.7 1 2 1 -0.0011 11 0 0 0 2.69E+08 2.52E+08 - - - 4.7759 1 221125_WJC_METTL3_EV_vs_WT_F08.06040.06040.2 4.77E-09 15/26 K.TTSESSSSPSASLK[136.11].G "sp|Q96CB8|INT12_HUMAN,tr|A0A087WXN4|A0A087WXN4_HUMAN" 2 1375.6558 1.27 111995 6040 2 1375.654635 688.8352 Integrator complex subunit 12 OS=Homo sapiens OX=9606 GN=INTS12 PE=1 SV=1 5.66 1567.3 - 1.38E+06 - - - -0.8607 - 2.837 0.683 - 879.6 1 2 0 -0.0012 14 0 0 0 1.55E+08 1.22E+08 - - - 6.702 0.9998 221125_WJC_METTL3_EV_vs_WT_F08.06042.06042.3 5.90E-06 15/52 R.IAMENDDGR[166.11]TEEEK[136.11].H "sp|Q8WWM7|ATX2L_HUMAN,tr|H3BSK9|H3BSK9_HUMAN,tr|H3BUF6|H3BUF6_HUMAN" 3 1653.7271 1.79 111997 6042 3 1653.723232 552.2496 Ataxin-2-like protein OS=Homo sapiens OX=9606 GN=ATXN2L PE=1 SV=2 4.08 1567.4 - 1.14E+06 - - - -2.339 - 3.088 0.534 - 395.2 1 2 1 -0.0039 14 0 0 0 7.24E+07 4.04E+07 - - - 7.4889 1 221125_WJC_METTL3_EV_vs_WT_F08.06043.06043.3 8.28E-07 14/52 K.QQVEQSSASQTGIK.Q "sp|Q9H4A3|WNK1_HUMAN,tr|F5GWT4|F5GWT4_HUMAN,tr|A0A6Q8PFM0|A0A6Q8PFM0_HUMAN" 3 1489.7372 5.52 111998 6043 3 1489.734427 497.5864 Serine\threonine-protein kinase WNK1 OS=Homo sapiens OX=9606 GN=WNK1 PE=1 SV=2 6 1567.5 - 1.13E+06 - - - -1.895 - 2.549 0.496 - 399.5 1 2 0 -0.0028 14 0 0 0 3.85E+07 6.97E+06 - - - 6.5558 0.9895 221125_WJC_METTL3_EV_vs_WT_F08.06044.06044.2 0.063 14-Aug R.LSK[136.11]EDIER[166.11].M "sp|P11142|HSP7C_HUMAN,tr|E9PNE6|E9PNE6_HUMAN,tr|A8K7Q2|A8K7Q2_HUMAN,tr|E9PKE3|E9PKE3_HUMAN,tr|E9PM13|E9PM13_HUMAN,tr|E9PS65|E9PS65_HUMAN" 6 1006.5414 0.14 111999 6044 2 1006.540223 504.278 Heat shock cognate 71 kDa protein OS=Homo sapiens OX=9606 GN=HSPA8 PE=1 SV=1 4.68 1567.6 - 990513 - - - -1.1644 - 1.833 0.242 - 281.9 1 2 1 -0.0012 8 0 0 0 3.40E+06 2.46E+07 - - - 2.6556 0.9997 221125_WJC_METTL3_EV_vs_WT_F08.06052.06052.3 4.77E-08 Dec-44 R.NIDEHANEDVER.M sp|P61026|RAB10_HUMAN 1 1439.6277 1.47 112005 6052 3 1439.619679 480.8832 Ras-related protein Rab-10 OS=Homo sapiens OX=9606 GN=RAB10 PE=1 SV=1 4.17 1568.5 - 1.08E+06 - - - -5.5716 - 2.421 0.618 - 280.5 1 2 0 -0.008 12 0 0 0 4.33E+08 2.95E+08 - - - 7.8787 0.9997 221125_WJC_METTL3_EV_vs_WT_F08.06057.06057.2 0.000157 24-Nov K.TSSEASVSSSVAK[136.11].N sp|Q9NXV6|CARF_HUMAN 1 1246.6132 0.07 112010 6057 2 1246.613374 624.3139 CDKN2A-interacting protein OS=Homo sapiens OX=9606 GN=CDKN2AIP PE=1 SV=3 5.66 1569.2 - 337001 - - - 0.1195 - 2.22 0.329 - 431.2 1 2 0 0.0001 13 0 0 0 3.16E+05 4.76E+06 - - - 3.5178 0.9999 221125_WJC_METTL3_EV_vs_WT_F08.06062.06062.2 3.82E-07 26-Dec K.KGPGEVAGTVTGQK[136.11].R "sp|Q86U44|MTA70_HUMAN,tr|F5H6D8|F5H6D8_HUMAN,tr|H0YFV6|H0YFV6_HUMAN,tr|B4DTN4|B4DTN4_HUMAN" 4 1335.7238 - 112013 6062 2 1335.722686 668.8692 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 8.59 1569.8 - 336067 - - - -0.8183 - 2.858 0.504 - 254.9 1 2 0 -0.0011 14 0 0 0 - - - - - 5.3984 0.9956 221125_WJC_METTL3_EV_vs_WT_F08.06063.06063.2 0.00388 20-Aug K.SESPKEPEQLR.K "sp|P09651|ROA1_HUMAN,tr|F8W646|F8W646_HUMAN,tr|A0A7I2V3R8|A0A7I2V3R8_HUMAN,tr|F8VTQ5|F8VTQ5_HUMAN,tr|A0A7I2YQ85|A0A7I2YQ85_HUMAN,tr|F8W6I7|F8W6I7_HUMAN,tr|A0A7I2V2L6|A0A7I2V2L6_HUMAN,tr|A0A7I2V3W0|A0A7I2V3W0_HUMAN" 8 1298.6466 0.87 112014 6063 2 1298.64559 650.3306 Heterogeneous nuclear ribonucleoprotein A1 OS=Homo sapiens OX=9606 GN=HNRNPA1 PE=1 SV=5 4.78 1569.9 - 340118 - - - -0.8116 - 1.839 0.365 - 215.4 1 2 1 -0.0011 11 0 0 0 5.65E+08 6.53E+08 - - - 3.3846 0.9992 221125_WJC_METTL3_EV_vs_WT_F08.06066.06066.3 0.000587 13/48 K.IQDK[136.11]EGIPPDQQR[166.11].L "sp|P62979|RS27A_HUMAN,sp|P0CG48|UBC_HUMAN,sp|P0CG48|UBC_HUMAN,sp|P0CG48|UBC_HUMAN,sp|P0CG48|UBC_HUMAN,sp|P0CG48|UBC_HUMAN,sp|P0CG48|UBC_HUMAN,sp|P0CG48|UBC_HUMAN,sp|P0CG48|UBC_HUMAN,sp|P0CG48|UBC_HUMAN,sp|P0CG47|UBB_HUMAN,sp|P0CG47|UBB_HUMAN,sp|P0CG47|UBB_HUMAN,sp|P62987|RL40_HUMAN,tr|F5H388|F5H388_HUMAN,tr|F5H388|F5H388_HUMAN,tr|F5GYU3|F5GYU3_HUMAN,tr|F5GYU3|F5GYU3_HUMAN,tr|B4DV12|B4DV12_HUMAN,tr|B4DV12|B4DV12_HUMAN,tr|J3QSA3|J3QSA3_HUMAN,tr|Q5PY61|Q5PY61_HUMAN,tr|Q5PY61|Q5PY61_HUMAN,tr|Q5PY61|Q5PY61_HUMAN,tr|F5H2Z3|F5H2Z3_HUMAN,tr|F5H2Z3|F5H2Z3_HUMAN,tr|M0R2S1|M0R2S1_HUMAN,tr|J3QS39|J3QS39_HUMAN,tr|J3QTR3|J3QTR3_HUMAN,tr|Q96C32|Q96C32_HUMAN,tr|Q96C32|Q96C32_HUMAN,tr|Q96C32|Q96C32_HUMAN,tr|Q96C32|Q96C32_HUMAN,tr|M0R1V7|M0R1V7_HUMAN,tr|F5H747|F5H747_HUMAN,tr|F5H747|F5H747_HUMAN,tr|F5GXK7|F5GXK7_HUMAN,tr|F5GXK7|F5GXK7_HUMAN,tr|M0R1M6|M0R1M6_HUMAN,tr|F5H6Q2|F5H6Q2_HUMAN,tr|F5H6Q2|F5H6Q2_HUMAN,tr|F5GZ39|F5GZ39_HUMAN,tr|J3QKN0|J3QKN0_HUMAN,tr|J3QKN0|J3QKN0_HUMAN,tr|F5H265|F5H265_HUMAN,tr|F5H265|F5H265_HUMAN,tr|A0A2R8Y422|A0A2R8Y422_HUMAN" 47 1540.7964 0.67 112015 6066 3 1540.795349 514.6061 Ubiquitin-40S ribosomal protein S27a OS=Homo sapiens OX=9606 GN=RPS27A PE=1 SV=2 4.56 1570.3 - 1.62E+06 - - - -0.7081 - 2.337 0.343 - 239.6 1 2 1 -0.0011 13 0 0 0 2.12E+08 3.13E+08 - - - 4.6653 1 221125_WJC_METTL3_EV_vs_WT_F08.06068.06068.2 6.45E-08 16/26 K.TTSESSSSPSASLK.G "sp|Q96CB8|INT12_HUMAN,tr|A0A087WXN4|A0A087WXN4_HUMAN" 2 1367.6416 1.26 112016 6068 2 1367.639915 684.8281 Integrator complex subunit 12 OS=Homo sapiens OX=9606 GN=INTS12 PE=1 SV=1 5.66 1570.6 - 5.18E+06 - - - -1.2459 - 2.942 0.614 - 1065.3 1 2 0 -0.0017 14 0 0 0 1.54E+08 1.22E+08 - - - 6.2834 0.9986 221125_WJC_METTL3_EV_vs_WT_F08.06070.06070.3 0.00147 Nov-48 K.IQDKEGIPPDQQR.L "sp|P62979|RS27A_HUMAN,sp|P0CG48|UBC_HUMAN,sp|P0CG48|UBC_HUMAN,sp|P0CG48|UBC_HUMAN,sp|P0CG48|UBC_HUMAN,sp|P0CG48|UBC_HUMAN,sp|P0CG48|UBC_HUMAN,sp|P0CG48|UBC_HUMAN,sp|P0CG48|UBC_HUMAN,sp|P0CG48|UBC_HUMAN,sp|P0CG47|UBB_HUMAN,sp|P0CG47|UBB_HUMAN,sp|P0CG47|UBB_HUMAN,sp|P62987|RL40_HUMAN,tr|F5H388|F5H388_HUMAN,tr|F5H388|F5H388_HUMAN,tr|F5GYU3|F5GYU3_HUMAN,tr|F5GYU3|F5GYU3_HUMAN,tr|B4DV12|B4DV12_HUMAN,tr|B4DV12|B4DV12_HUMAN,tr|J3QSA3|J3QSA3_HUMAN,tr|Q5PY61|Q5PY61_HUMAN,tr|Q5PY61|Q5PY61_HUMAN,tr|Q5PY61|Q5PY61_HUMAN,tr|F5H2Z3|F5H2Z3_HUMAN,tr|F5H2Z3|F5H2Z3_HUMAN,tr|M0R2S1|M0R2S1_HUMAN,tr|J3QS39|J3QS39_HUMAN,tr|J3QTR3|J3QTR3_HUMAN,tr|Q96C32|Q96C32_HUMAN,tr|Q96C32|Q96C32_HUMAN,tr|Q96C32|Q96C32_HUMAN,tr|Q96C32|Q96C32_HUMAN,tr|M0R1V7|M0R1V7_HUMAN,tr|F5H747|F5H747_HUMAN,tr|F5H747|F5H747_HUMAN,tr|F5GXK7|F5GXK7_HUMAN,tr|F5GXK7|F5GXK7_HUMAN,tr|M0R1M6|M0R1M6_HUMAN,tr|F5H6Q2|F5H6Q2_HUMAN,tr|F5H6Q2|F5H6Q2_HUMAN,tr|F5GZ39|F5GZ39_HUMAN,tr|J3QKN0|J3QKN0_HUMAN,tr|J3QKN0|J3QKN0_HUMAN,tr|F5H265|F5H265_HUMAN,tr|F5H265|F5H265_HUMAN,tr|A0A2R8Y422|A0A2R8Y422_HUMAN" 47 1522.774 0.69 112018 6070 3 1522.772828 508.5986 Ubiquitin-40S ribosomal protein S27a OS=Homo sapiens OX=9606 GN=RPS27A PE=1 SV=2 4.56 1570.8 - 1.36E+06 - - - -0.7499 - 2.25 0.312 - 201 1 2 1 -0.0011 13 0 0 0 1.74E+08 2.51E+08 - - - 4.2168 0.9917 221125_WJC_METTL3_EV_vs_WT_F08.06071.06071.2 2.83E-06 18-Aug K.HTDESLGDC[160.03]S.F "sp|Q86U44|MTA70_HUMAN,tr|H0YFV6|H0YFV6_HUMAN" 2 1119.4139 - 112019 6071 2 1119.412438 560.7142 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 4.02 1570.9 - 597726 - - - -1.2766 - 1.804 0.609 - 243.4 1 1 0 -0.0014 10 0 0 0 - - - - - 5.1855 1 221125_WJC_METTL3_EV_vs_WT_F08.06074.06074.2 1.59E-06 18/26 K.K[136.11]GPGEVAGTVTGQK[136.11].R "sp|Q86U44|MTA70_HUMAN,tr|F5H6D8|F5H6D8_HUMAN,tr|H0YFV6|H0YFV6_HUMAN,tr|B4DTN4|B4DTN4_HUMAN" 4 1343.738 0 112021 6074 2 1343.735734 672.8763 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 8.59 1571.2 - 1.25E+07 - - - -1.6707 - 3.453 0.579 - 779.2 1 2 0 -0.0022 14 0 0 0 1.76E+09 5.79E+11 - - - 6.4266 0.8339 221125_WJC_METTL3_EV_vs_WT_F08.06080.06080.2 0.0365 15/18 L.LEQYK[136.11]EESK[136.11]K[136.11].A "sp|Q00839|HNRPU_HUMAN,tr|A0A1W2PQL0|A0A1W2PQL0_HUMAN,tr|A0A1W2PPL4|A0A1W2PPL4_HUMAN,tr|Q5RI18|Q5RI18_HUMAN,tr|A0A1W2PP35|A0A1W2PP35_HUMAN,tr|A0A1W2PPS1|A0A1W2PPS1_HUMAN,tr|A0A1W2PPH7|A0A1W2PPH7_HUMAN,tr|A0A1W2PQD4|A0A1W2PQD4_HUMAN,tr|A0A1W2PP34|A0A1W2PP34_HUMAN,tr|A0A1X7SBS1|A0A1X7SBS1_HUMAN" 10 1304.7038 1.16 112024 6080 2 1304.702519 653.3592 Heterogeneous nuclear ribonucleoprotein U OS=Homo sapiens OX=9606 GN=HNRNPU PE=1 SV=6 6.23 1571.9 - 1.60E+06 - - - -1.0064 - 2.778 0.26 - 1022.6 1 1 1 -0.0013 10 0 0 0 9.01E+07 7.75E+07 - - - 3.8129 0.9997 221125_WJC_METTL3_EV_vs_WT_F08.06085.06085.3 0.00116 13/40 K.SESPKEPEQLR.K "sp|P09651|ROA1_HUMAN,tr|F8W646|F8W646_HUMAN,tr|A0A7I2V3R8|A0A7I2V3R8_HUMAN,tr|F8VTQ5|F8VTQ5_HUMAN,tr|A0A7I2YQ85|A0A7I2YQ85_HUMAN,tr|F8W6I7|F8W6I7_HUMAN,tr|A0A7I2V2L6|A0A7I2V2L6_HUMAN,tr|A0A7I2V3W0|A0A7I2V3W0_HUMAN" 8 1298.6466 1.37 112027 6085 3 1298.645728 433.8895 Heterogeneous nuclear ribonucleoprotein A1 OS=Homo sapiens OX=9606 GN=HNRNPA1 PE=1 SV=5 4.78 1572.4 - 6.10E+06 - - - -0.7053 - 2.712 0.387 - 311.6 1 2 1 -0.0009 11 0 0 0 6.30E+09 4.60E+09 - - - 5.6887 0.9998 221125_WJC_METTL3_EV_vs_WT_F08.06087.06087.2 0.000157 13/32 R.AGQSAAGAAPGGGVDTR[166.11].D "sp|P21333|FLNA_HUMAN,tr|A0A7P0NMY4|A0A7P0NMY4_HUMAN,tr|A0A7I2V3E6|A0A7I2V3E6_HUMAN,tr|A0A087WWY3|A0A087WWY3_HUMAN" 4 1451.6992 0.96 112029 6087 2 1451.696605 726.8569 Filamin-A OS=Homo sapiens OX=9606 GN=FLNA PE=1 SV=4 5.88 1572.7 - 238176 - - - -1.8144 - 2.7 0.52 - 449.5 1 2 0 -0.0026 17 0 0 0 3.73E+07 3.87E+07 - - - 5.3228 0.9999 221125_WJC_METTL3_EV_vs_WT_F08.06095.06095.2 5.38E-08 24-Oct R.EGSTQQLQTTSPK[136.11].V "sp|Q5T8P6|RBM26_HUMAN,tr|A0A087X0H9|A0A087X0H9_HUMAN" 2 1411.7034 0.96 112033 6095 2 1411.702971 706.859 RNA-binding protein 26 OS=Homo sapiens OX=9606 GN=RBM26 PE=1 SV=3 6.1 1573.7 - 372911 - - - -0.3308 - 2.095 0.561 - 411.9 1 2 0 -0.0005 13 0 0 0 1.17E+08 1.22E+08 - - - 5.0825 0.8537 221125_WJC_METTL3_EV_vs_WT_F08.06099.06099.3 0.452 Jul-36 R.KESEFDDEPK[136.11].F "sp|Q9Y2W1|TR150_HUMAN,tr|A0A3B3ITZ9|A0A3B3ITZ9_HUMAN" 2 1230.5496 - 112035 6099 3 1230.546901 411.1905 Thyroid hormone receptor-associated protein 3 OS=Homo sapiens OX=9606 GN=THRAP3 PE=1 SV=2 4.18 1574.2 - 199333 - - - -2.1633 - 1.167 0.144 - 61 1 2 0 -0.0027 10 0 0 0 - - - - - 0.5957 0.9998 221125_WJC_METTL3_EV_vs_WT_F08.06108.06108.2 1.06E-06 13/22 R.NIDEHANEDVER.M sp|P61026|RAB10_HUMAN 1 1439.6277 1.34 112039 6108 2 1439.624733 720.8211 Ras-related protein Rab-10 OS=Homo sapiens OX=9606 GN=RAB10 PE=1 SV=1 4.17 1575.3 - 729922 - - - -2.0609 - 2.06 0.583 - 597.6 1 2 0 -0.003 12 0 0 0 3.32E+07 2.48E+07 - - - 5.2477 1 221125_WJC_METTL3_EV_vs_WT_F08.06110.06110.2 3.14E-06 14/32 R.AGQSAAGAAPGGGVDTR.D "sp|P21333|FLNA_HUMAN,tr|A0A7P0NMY4|A0A7P0NMY4_HUMAN,tr|A0A7I2V3E6|A0A7I2V3E6_HUMAN,tr|A0A087WWY3|A0A087WWY3_HUMAN" 4 1441.691 0.96 112040 6110 2 1441.692689 721.8528 Filamin-A OS=Homo sapiens OX=9606 GN=FLNA PE=1 SV=4 5.88 1575.5 - 564636 - - - 1.193 - 2.692 0.576 - 587.8 1 2 0 0.0017 17 0 0 0 3.73E+07 3.87E+07 - - - 5.7295 0.9999 221125_WJC_METTL3_EV_vs_WT_F08.06112.06112.2 1.81E-06 24-Nov R.EGSTQQLQTTSPK.V "sp|Q5T8P6|RBM26_HUMAN,tr|A0A087X0H9|A0A087X0H9_HUMAN" 2 1403.6892 0.96 112041 6112 2 1403.691049 702.8519 RNA-binding protein 26 OS=Homo sapiens OX=9606 GN=RBM26 PE=1 SV=3 6.1 1575.8 - 547648 - - - 1.2902 - 2.349 0.584 - 492.8 1 2 0 0.0018 13 0 0 0 1.17E+08 1.22E+08 - - - 5.5456 0.999 221125_WJC_METTL3_EV_vs_WT_F08.06113.06113.2 0.0265 28-Sep K.AEDGATPSPSNETPK.K sp|P29966|MARCS_HUMAN 1 1499.674 0.89 112042 6113 2 1499.671905 750.8443 Myristoylated alanine-rich C-kinase substrate OS=Homo sapiens OX=9606 GN=MARCKS PE=1 SV=4 4.14 1575.9 - 339793 - - - -1.3843 - 1.552 0.347 - 126.2 1 2 0 -0.0021 15 0 0 0 1.05E+08 1.19E+08 - - - 2.6839 1 221125_WJC_METTL3_EV_vs_WT_F08.06117.06117.3 5.39E-07 13/52 K.K[136.11]GPGEVAGTVTGQK[136.11].R "sp|Q86U44|MTA70_HUMAN,tr|F5H6D8|F5H6D8_HUMAN,tr|H0YFV6|H0YFV6_HUMAN,tr|B4DTN4|B4DTN4_HUMAN" 4 1343.738 0 112044 6117 3 1343.735842 448.9199 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 8.59 1576.4 - 8.42E+07 - - - -1.5903 - 2.808 0.534 - 310.4 1 2 0 -0.0021 14 0 0 0 1.08E+08 1.02E+12 - - - 7.2368 0.8287 221125_WJC_METTL3_EV_vs_WT_F08.06126.06126.2 0.00838 16-Sep A.SPK[136.11]EPEQLR[166.11].K "sp|Q32P51|RA1L2_HUMAN,sp|P09651|ROA1_HUMAN,tr|F8W646|F8W646_HUMAN,tr|F8VZ49|F8VZ49_HUMAN,tr|A0A7I2V3R8|A0A7I2V3R8_HUMAN,tr|F8VTQ5|F8VTQ5_HUMAN,tr|A0A7I2YQ85|A0A7I2YQ85_HUMAN,tr|F8W6I7|F8W6I7_HUMAN,tr|A0A7I2V2L6|A0A7I2V2L6_HUMAN,tr|A0A7I2V3W0|A0A7I2V3W0_HUMAN" 10 1100.5945 1.37 112049 6126 2 1100.593382 551.3045 Heterogeneous nuclear ribonucleoprotein A1-like 2 OS=Homo sapiens OX=9606 GN=HNRNPA1L2 PE=2 SV=2 5.86 1577.5 - 445190 - - - -1.0095 - 2.055 0.358 - 318 1 1 1 -0.0011 9 0 0 0 2.29E+08 1.66E+08 - - - 3.7686 0.9164 221125_WJC_METTL3_EV_vs_WT_F08.06145.06145.3 0.195 Jun-36 R.SHEGETSYIR.V sp|Q13242|SRSF9_HUMAN 1 1177.5364 1.81 112059 6145 3 1177.534859 393.5194 Serine\arginine-rich splicing factor 9 OS=Homo sapiens OX=9606 GN=SRSF9 PE=1 SV=1 5.38 1579.9 - 230258 - - - -1.2798 - 1.351 0.121 - 49.4 2 2 0 -0.0015 10 0 0 0 4.64E+07 2.57E+07 - - - 0.6279 0.9999 221125_WJC_METTL3_EV_vs_WT_F08.06147.06147.2 9.01E-06 28-Dec K.AEDGATPSPSNETPK[136.11].K sp|P29966|MARCS_HUMAN 1 1507.6882 0.88 112060 6147 2 1507.6876 754.8514 Myristoylated alanine-rich C-kinase substrate OS=Homo sapiens OX=9606 GN=MARCKS PE=1 SV=4 4.14 1580.1 - 430791 - - - -0.3854 - 2.379 0.479 - 317.8 1 2 0 -0.0006 15 0 0 0 8.80E+07 9.99E+07 - - - 4.7095 0.9925 221125_WJC_METTL3_EV_vs_WT_F08.06152.06152.3 0.000406 13/52 S.YAAQQHPQAAASYR[166.11].G sp|Q96PK6|RBM14_HUMAN 1 1570.7516 2.7 112063 6152 3 1570.751613 524.5911 RNA-binding protein 14 OS=Homo sapiens OX=9606 GN=RBM14 PE=1 SV=2 8.6 1580.8 - 346805 - - - 0.0025 - 2.336 0.424 - 141.8 1 1 0 0 14 0 0 0 1.74E+08 6.45E+07 - - - 5.5219 0.998 221125_WJC_METTL3_EV_vs_WT_F08.06158.06158.2 5.31E-07 20-Oct R.VK[136.11]VETYNDESR[166.11].L "sp|P27694|RFA1_HUMAN,tr|I3L4R8|I3L4R8_HUMAN" 2 1356.664 1.37 112065 6158 2 1356.661524 679.3393 Replication protein A 70 kDa DNA-binding subunit OS=Homo sapiens OX=9606 GN=RPA1 PE=1 SV=2 4.68 1581.6 - 870904 - - - -1.8464 - 2.014 0.605 - 249.8 1 2 1 -0.0025 11 0 0 0 6.77E+07 4.95E+07 - - - 5.4027 0.8868 221125_WJC_METTL3_EV_vs_WT_F08.06163.06163.3 0.918 Nov-44 K.LQELEQQR[166.11]EEQK[136.11].R "sp|Q02040|AK17A_HUMAN,tr|X6RAJ1|X6RAJ1_HUMAN" 2 1574.8019 1.91 112067 6163 3 1574.801161 525.9412 A-kinase anchor protein 17A OS=Homo sapiens OX=9606 GN=AKAP17A PE=1 SV=2 4.49 1582.2 - 331883 - - - -0.482 - 1.873 0.084 - 132.4 1 2 1 -0.0008 12 0 0 0 2.93E+07 1.54E+07 - - - 1.2158 1 221125_WJC_METTL3_EV_vs_WT_F08.06168.06168.2 1.44E-07 17/28 K.SGGGGGGGGSSWGGR.S sp|Q13151|ROA0_HUMAN 1 1191.5017 1.34 112069 6168 2 1191.498994 596.7581 Heterogeneous nuclear ribonucleoprotein A0 OS=Homo sapiens OX=9606 GN=HNRNPA0 PE=1 SV=1 9.47 1582.8 - 708925 - - - -2.2803 - 3.14 0.581 - 764 1 2 0 -0.0027 15 0 0 0 2.37E+08 1.76E+08 - - - 6.1445 0.9996 221125_WJC_METTL3_EV_vs_WT_F08.06175.06175.3 0.0242 Dec-40 K.SESPK[136.11]EPEQLR[166.11].K "sp|P09651|ROA1_HUMAN,tr|F8W646|F8W646_HUMAN,tr|A0A7I2V3R8|A0A7I2V3R8_HUMAN,tr|F8VTQ5|F8VTQ5_HUMAN,tr|A0A7I2YQ85|A0A7I2YQ85_HUMAN,tr|F8W6I7|F8W6I7_HUMAN,tr|A0A7I2V2L6|A0A7I2V2L6_HUMAN,tr|A0A7I2V3W0|A0A7I2V3W0_HUMAN" 8 1316.6691 1.4 112072 6175 3 1316.669095 439.897 Heterogeneous nuclear ribonucleoprotein A1 OS=Homo sapiens OX=9606 GN=HNRNPA1 PE=1 SV=5 4.78 1583.7 - 2.53E+07 - - - -0.0144 - 2.597 0.364 - 268.9 1 2 1 0 11 0 0 0 6.70E+09 4.79E+09 - - - 5.3094 1 221125_WJC_METTL3_EV_vs_WT_F08.06177.06177.2 8.71E-12 19/28 K.SGGGGGGGGSSWGGR[166.11].S sp|Q13151|ROA0_HUMAN 1 1201.51 1.34 112073 6177 2 1201.508958 601.7623 Heterogeneous nuclear ribonucleoprotein A0 OS=Homo sapiens OX=9606 GN=HNRNPA0 PE=1 SV=1 9.47 1583.9 - 1.13E+06 - - - -0.8514 - 3.718 0.629 - 1645.1 1 2 0 -0.001 15 0 0 0 2.37E+08 1.76E+08 - - - 6.915 0.9981 221125_WJC_METTL3_EV_vs_WT_F08.06179.06179.2 0.00208 20-Nov K.SESPK[136.11]EPEQLR[166.11].K "sp|P09651|ROA1_HUMAN,tr|F8W646|F8W646_HUMAN,tr|A0A7I2V3R8|A0A7I2V3R8_HUMAN,tr|F8VTQ5|F8VTQ5_HUMAN,tr|A0A7I2YQ85|A0A7I2YQ85_HUMAN,tr|F8W6I7|F8W6I7_HUMAN,tr|A0A7I2V2L6|A0A7I2V2L6_HUMAN,tr|A0A7I2V3W0|A0A7I2V3W0_HUMAN" 8 1316.6691 1.36 112074 6179 2 1316.668282 659.3418 Heterogeneous nuclear ribonucleoprotein A1 OS=Homo sapiens OX=9606 GN=HNRNPA1 PE=1 SV=5 4.78 1584.2 - 1.62E+06 - - - -0.6319 - 2.179 0.443 - 439 1 2 1 -0.0008 11 0 0 0 4.96E+08 3.65E+08 - - - 4.4198 0.9995 221125_WJC_METTL3_EV_vs_WT_F08.06181.06181.2 0.000158 18-Oct R.THTAFPGTDK.L sp|Q96F45|ZN503_HUMAN 1 1073.5142 1.36 112075 6181 2 1073.516251 537.7644 Zinc finger protein 503 OS=Homo sapiens OX=9606 GN=ZNF503 PE=1 SV=1 6.41 1584.4 - 364988 - - - 1.9348 - 1.875 0.43 - 388.6 1 2 0 0.0021 10 0 0 0 4.00E+07 2.94E+07 - - - 3.971 0.9996 221125_WJC_METTL3_EV_vs_WT_F08.06183.06183.3 0.00456 Jul-36 R.SHEGETSYIR[166.11].V sp|Q13242|SRSF9_HUMAN 1 1187.5446 1.84 112077 6183 3 1187.545512 396.8555 Serine\arginine-rich splicing factor 9 OS=Homo sapiens OX=9606 GN=SRSF9 PE=1 SV=1 5.38 1584.6 - 306649 - - - 0.7377 - 1.41 0.397 - 98.8 1 2 0 0.0009 10 0 0 0 4.64E+07 2.52E+07 - - - 3.9693 0.878 221125_WJC_METTL3_EV_vs_WT_F08.06186.06186.3 0.46 Sep-40 K.SESPKEPEQLR[166.11].K "sp|P09651|ROA1_HUMAN,tr|F8W646|F8W646_HUMAN,tr|A0A7I2V3R8|A0A7I2V3R8_HUMAN,tr|F8VTQ5|F8VTQ5_HUMAN,tr|A0A7I2YQ85|A0A7I2YQ85_HUMAN,tr|F8W6I7|F8W6I7_HUMAN,tr|A0A7I2V2L6|A0A7I2V2L6_HUMAN,tr|A0A7I2V3W0|A0A7I2V3W0_HUMAN" 8 1308.6549 - 112078 6186 3 1308.651399 437.2256 Heterogeneous nuclear ribonucleoprotein A1 OS=Homo sapiens OX=9606 GN=HNRNPA1 PE=1 SV=5 4.78 1585 - 391252 - - - -2.686 - 1.532 0.184 - 92.1 1 2 1 -0.0035 11 0 0 0 - - - - - 1.8023 0.9986 221125_WJC_METTL3_EV_vs_WT_F08.06190.06190.2 0.0263 18-Oct R.R[166.11]DFAPPGQQK[136.11].R sp|Q9BVC6|TM109_HUMAN 1 1160.6057 0.95 112081 6190 2 1160.606398 581.3101 Transmembrane protein 109 OS=Homo sapiens OX=9606 GN=TMEM109 PE=1 SV=1 8.75 1585.5 - 320788 - - - 0.579 - 1.749 0.216 - 350 1 2 0 0.0007 10 0 0 0 4.39E+07 4.61E+07 - - - 2.1966 0.9998 221125_WJC_METTL3_EV_vs_WT_F08.06197.06197.2 0.000864 24-Nov K.EQTFSGGTSQDTK.A "sp|Q9Y2W1|TR150_HUMAN,tr|A0A3B3ITZ9|A0A3B3ITZ9_HUMAN" 2 1384.6107 5.45 112084 6197 2 1384.608503 693.3126 Thyroid hormone receptor-associated protein 3 OS=Homo sapiens OX=9606 GN=THRAP3 PE=1 SV=2 4.37 1586.4 - 529043 - - - -1.5528 - 2.033 0.544 - 473.8 1 2 0 -0.0022 13 0 0 0 2.08E+07 3.82E+06 - - - 4.8793 0.9861 221125_WJC_METTL3_EV_vs_WT_F08.06204.06204.4 0.0574 16/72 R.LGHAEQK[136.11]DEMVPR[166.11].L sp|Q9P258|RCC2_HUMAN 1 1526.763 0.001 112087 6204 4 1526.764099 382.698 Protein RCC2 OS=Homo sapiens OX=9606 GN=RCC2 PE=1 SV=2 5.45 1587.3 - 411840 - - - 0.6989 - 1.927 0.239 - 187.9 1 2 1 0.0011 13 0 0 0 0.00E+00 1.51E+07 - - - 1.5492 0.9971 221125_WJC_METTL3_EV_vs_WT_F08.06205.06205.2 0.00555 18-Oct R.RDFAPPGQQK.R sp|Q9BVC6|TM109_HUMAN 1 1142.5833 0.95 112088 6205 2 1142.580047 572.2989 Transmembrane protein 109 OS=Homo sapiens OX=9606 GN=TMEM109 PE=1 SV=1 8.75 1587.5 - 319434 - - - -2.8085 - 1.838 0.257 - 414.4 1 2 0 -0.0032 10 0 0 0 4.39E+07 4.61E+07 - - - 2.6372 0.9998 221125_WJC_METTL3_EV_vs_WT_F08.06214.06214.2 7.48E-05 28-Dec M.PGPTPSGTNVGSSGR[166.11].S sp|P60468|SC61B_HUMAN 1 1379.6669 1.32 112092 6214 2 1379.664789 690.8407 Protein transport protein Sec61 subunit beta OS=Homo sapiens OX=9606 GN=SEC61B PE=1 SV=2 10.18 1588.7 - 677947 - - - -1.5127 - 2.184 0.496 - 274.9 1 2 0 -0.0021 15 0 0 0 2.03E+08 1.53E+08 - - - 4.6243 0.9999 221125_WJC_METTL3_EV_vs_WT_F08.06221.06221.2 0.000174 15/28 M.PGPTPSGTNVGSSGR.S sp|P60468|SC61B_HUMAN 1 1369.6586 1.3 112096 6221 2 1369.656238 685.8366 Protein transport protein Sec61 subunit beta OS=Homo sapiens OX=9606 GN=SEC61B PE=1 SV=2 10.18 1589.4 - 907298 - - - -1.7289 - 2.463 0.6 - 494 1 2 0 -0.0024 15 0 0 0 2.03E+08 1.57E+08 - - - 5.6879 0.9999 221125_WJC_METTL3_EV_vs_WT_F08.06235.06235.3 0.00355 Sep-36 R.KESEFDDEPK.F "sp|Q9Y2W1|TR150_HUMAN,tr|A0A3B3ITZ9|A0A3B3ITZ9_HUMAN" 2 1222.5354 2.21 112102 6235 3 1222.53345 408.5191 Thyroid hormone receptor-associated protein 3 OS=Homo sapiens OX=9606 GN=THRAP3 PE=1 SV=2 4.18 1591.3 - 2.09E+07 - - - -1.5648 - 1.984 0.511 - 104.5 1 2 0 -0.0019 10 0 0 0 1.93E+09 8.75E+08 - - - 6.2374 0.9978 221125_WJC_METTL3_EV_vs_WT_F08.06236.06236.3 0.00227 Oct-44 K.ADK[136.11]NEVAAEVAK[136.11].L "sp|P56192|SYMC_HUMAN,tr|H0YIP0|H0YIP0_HUMAN" 2 1259.6692 0.85 112103 6236 3 1259.665285 420.897 "Methionine--tRNA ligase, cytoplasmic OS=Homo sapiens OX=9606 GN=MARS1 PE=1 SV=2" 4.68 1591.4 - 908147 - - - -3.1326 - 2.154 0.394 - 182.4 1 2 1 -0.0039 12 0 0 0 7.33E+07 8.68E+07 - - - 5.0585 0.9917 221125_WJC_METTL3_EV_vs_WT_F08.06237.06237.2 2.53E-08 13/22 Q.C[160.03]C[160.03]EASSSDITEK.S "sp|P52732|KIF11_HUMAN,tr|A0A7I2V3A9|A0A7I2V3A9_HUMAN" 2 1385.5439 22.56 112104 6237 2 1385.54181 693.7792 Kinesin-like protein KIF11 OS=Homo sapiens OX=9606 GN=KIF11 PE=1 SV=2 4.14 1591.5 - 490932 - - - -1.5055 - 2.341 0.57 - 596.3 1 1 0 -0.0021 12 0 0 0 2.09E+07 9.26E+05 - - - 5.4884 0.9997 221125_WJC_METTL3_EV_vs_WT_F08.06239.06239.3 0.008 Nov-52 K.K[136.11]GPGEVAGTVTGQK.R "sp|Q86U44|MTA70_HUMAN,tr|F5H6D8|F5H6D8_HUMAN,tr|H0YFV6|H0YFV6_HUMAN,tr|B4DTN4|B4DTN4_HUMAN" 4 1335.7238 - 112105 6239 3 1335.723352 446.2485 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 8.59 1591.7 - 9.75E+06 - - - -0.3197 - 2.124 0.329 - 215.8 1 2 0 -0.0004 14 0 0 0 - - - - - 4.2098 1 221125_WJC_METTL3_EV_vs_WT_F08.06251.06251.2 1.33E-05 15/18 R.KESEFDDEPK.F "sp|Q9Y2W1|TR150_HUMAN,tr|A0A3B3ITZ9|A0A3B3ITZ9_HUMAN" 2 1222.5354 2.89 112109 6251 2 1222.534719 612.275 Thyroid hormone receptor-associated protein 3 OS=Homo sapiens OX=9606 GN=THRAP3 PE=1 SV=2 4.18 1593.3 - 6.65E+06 - - - -0.5268 - 2.756 0.598 - 845.4 1 2 0 -0.0006 10 0 0 0 4.81E+08 1.67E+08 - - - 6.2874 0.9988 221125_WJC_METTL3_EV_vs_WT_F08.06253.06253.2 0.00785 16-Sep R.KLLEGEEC[160.03]R.M "sp|Q86Y46|K2C73_HUMAN,sp|Q7RTS7|K2C74_HUMAN,sp|P48668|K2C6C_HUMAN,sp|Q01546|K22O_HUMAN,sp|P12036|NFH_HUMAN,sp|P04259|K2C6B_HUMAN,sp|P13647|K2C5_HUMAN,sp|P35908|K22E_HUMAN,sp|O95678|K2C75_HUMAN,sp|P02538|K2C6A_HUMAN,tr|H0YI76|H0YI76_HUMAN,tr|H0YIC5|H0YIC5_HUMAN,tr|F8W1S1|F8W1S1_HUMAN" 13 1132.5547 16.36 112110 6253 2 1132.55149 567.2846 "Keratin, type II cytoskeletal 73 OS=Homo sapiens OX=9606 GN=KRT73 PE=1 SV=1" 4.79 1593.5 - 239706 - - - -2.7972 - 1.907 0.355 - 307.4 1 2 0 -0.0032 9 0 0 0 1.69E+07 1.03E+06 - - - 3.5296 0.9999 221125_WJC_METTL3_EV_vs_WT_F08.06257.06257.3 0.000506 Dec-36 R.K[136.11]GESGQSWPR[166.11].L "sp|Q15185|TEBP_HUMAN,tr|B4DDC6|B4DDC6_HUMAN,tr|A0A087WYT3|A0A087WYT3_HUMAN" 3 1148.5693 0.001 112111 6257 3 1148.566965 383.8637 Prostaglandin E synthase 3 OS=Homo sapiens OX=9606 GN=PTGES3 PE=1 SV=1 8.75 1594.1 - 1.40E+06 - - - -2.0687 - 2.177 0.444 - 261 1 2 0 -0.0024 10 0 0 0 0.00E+00 1.38E+08 - - - 5.7614 0.9998 221125_WJC_METTL3_EV_vs_WT_F08.06265.06265.3 0.00124 Sep-36 R.K[136.11]ESEFDDEPK[136.11].F "sp|Q9Y2W1|TR150_HUMAN,tr|A0A3B3ITZ9|A0A3B3ITZ9_HUMAN" 2 1238.5638 3.02 112116 6265 3 1238.56201 413.8619 Thyroid hormone receptor-associated protein 3 OS=Homo sapiens OX=9606 GN=THRAP3 PE=1 SV=2 4.18 1595.1 - 6.24E+06 - - - -1.4153 - 1.614 0.446 - 120.1 1 2 0 -0.0018 10 0 0 0 1.71E+09 5.67E+08 - - - 4.91 1 221125_WJC_METTL3_EV_vs_WT_F08.06271.06271.2 7.10E-05 15/18 R.K[136.11]ESEFDDEPK[136.11].F "sp|Q9Y2W1|TR150_HUMAN,tr|A0A3B3ITZ9|A0A3B3ITZ9_HUMAN" 2 1238.5638 2.89 112121 6271 2 1238.563374 620.2892 Thyroid hormone receptor-associated protein 3 OS=Homo sapiens OX=9606 GN=THRAP3 PE=1 SV=2 4.18 1595.7 - 1.82E+06 - - - -0.3141 - 2.734 0.561 - 831 1 2 0 -0.0004 10 0 0 0 4.73E+08 1.64E+08 - - - 5.9918 0.9999 221125_WJC_METTL3_EV_vs_WT_F08.06284.06284.3 0.000421 Dec-36 K.TENNDHINLK[136.11].V sp|P61956|SUMO2_HUMAN 1 1204.5928 1.02 112126 6284 3 1204.590303 402.5382 Small ubiquitin-related modifier 2 OS=Homo sapiens OX=9606 GN=SUMO2 PE=1 SV=3 5.29 1597.3 - 2.43E+06 - - - -2.0438 - 2.355 0.473 - 261.5 1 2 0 -0.0025 10 0 0 0 1.91E+08 1.87E+08 - - - 6.3143 0.8825 221125_WJC_METTL3_EV_vs_WT_F08.06291.06291.2 0.259 14-Sep V.AGTVTGQK[136.11].R "sp|Q86U44|MTA70_HUMAN,tr|F5H6D8|F5H6D8_HUMAN,tr|H0YFV6|H0YFV6_HUMAN,tr|B4DTN4|B4DTN4_HUMAN" 4 768.4221 0.15 112130 6291 2 768.420483 385.2183 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 8.8 1598.1 - 2.39E+06 - - - -2.1277 - 1.734 0.234 - 401.7 1 1 0 -0.0016 8 0 0 0 6.91E+08 4.47E+09 - - - 2.4289 1 221125_WJC_METTL3_EV_vs_WT_F08.06292.06292.2 6.93E-09 14/28 R.EGGDGEEQDVGDAGR[166.11].L sp|Q8N1G4|LRC47_HUMAN 1 1499.6 0.83 112131 6292 2 1499.596491 750.8073 Leucine-rich repeat-containing protein 47 OS=Homo sapiens OX=9606 GN=LRRC47 PE=1 SV=1 3.71 1598.2 - 890515 - - - -2.3253 - 2.326 0.718 - 356.6 1 2 0 -0.0035 15 0 0 0 4.33E+07 5.22E+07 - - - 6.4184 0.9992 221125_WJC_METTL3_EV_vs_WT_F08.06304.06304.2 0.377 18-Nov R.RQQEVETELK.M "sp|P08621|RU17_HUMAN,tr|M0QX04|M0QX04_HUMAN,tr|M0QYR1|M0QYR1_HUMAN" 3 1258.6517 1.5 112137 6304 2 1258.651308 630.3331 U1 small nuclear ribonucleoprotein 70 kDa OS=Homo sapiens OX=9606 GN=SNRNP70 PE=1 SV=2 4.79 1599.7 - 762087 - - - -0.3353 - 2.057 0.211 - 411.4 1 2 0 -0.0004 10 0 0 0 5.39E+07 3.59E+07 - - - 2.6125 0.9999 221125_WJC_METTL3_EV_vs_WT_F08.06307.06307.2 0.00419 16/26 K.KGPGEVAGTVTGQK[136.11].R "sp|Q86U44|MTA70_HUMAN,tr|F5H6D8|F5H6D8_HUMAN,tr|H0YFV6|H0YFV6_HUMAN,tr|B4DTN4|B4DTN4_HUMAN" 4 1335.7238 - 112139 6307 2 1335.722552 668.8692 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 8.59 1600 - 8.14E+06 - - - -0.9186 - 3.264 0.487 - 491.4 1 2 0 -0.0012 14 0 0 0 - - - - - 5.6062 0.9959 221125_WJC_METTL3_EV_vs_WT_F08.06309.06309.2 0.00163 20-Nov K.SESPKEPEQLR.K "sp|P09651|ROA1_HUMAN,tr|F8W646|F8W646_HUMAN,tr|A0A7I2V3R8|A0A7I2V3R8_HUMAN,tr|F8VTQ5|F8VTQ5_HUMAN,tr|A0A7I2YQ85|A0A7I2YQ85_HUMAN,tr|F8W6I7|F8W6I7_HUMAN,tr|A0A7I2V2L6|A0A7I2V2L6_HUMAN,tr|A0A7I2V3W0|A0A7I2V3W0_HUMAN" 8 1298.6466 0.87 112140 6309 2 1298.645139 650.3306 Heterogeneous nuclear ribonucleoprotein A1 OS=Homo sapiens OX=9606 GN=HNRNPA1 PE=1 SV=5 4.78 1600.2 - 6.36E+06 - - - -1.1589 - 2.021 0.366 - 406.4 1 2 1 -0.0015 11 0 0 0 5.65E+08 6.53E+08 - - - 3.6472 0.9997 221125_WJC_METTL3_EV_vs_WT_F08.06312.06312.3 0.000371 15/48 K.IQDK[136.11]EGIPPDQQR[166.11].L "sp|P62979|RS27A_HUMAN,sp|P0CG48|UBC_HUMAN,sp|P0CG48|UBC_HUMAN,sp|P0CG48|UBC_HUMAN,sp|P0CG48|UBC_HUMAN,sp|P0CG48|UBC_HUMAN,sp|P0CG48|UBC_HUMAN,sp|P0CG48|UBC_HUMAN,sp|P0CG48|UBC_HUMAN,sp|P0CG48|UBC_HUMAN,sp|P0CG47|UBB_HUMAN,sp|P0CG47|UBB_HUMAN,sp|P0CG47|UBB_HUMAN,sp|P62987|RL40_HUMAN,tr|F5H388|F5H388_HUMAN,tr|F5H388|F5H388_HUMAN,tr|F5GYU3|F5GYU3_HUMAN,tr|F5GYU3|F5GYU3_HUMAN,tr|B4DV12|B4DV12_HUMAN,tr|B4DV12|B4DV12_HUMAN,tr|J3QSA3|J3QSA3_HUMAN,tr|Q5PY61|Q5PY61_HUMAN,tr|Q5PY61|Q5PY61_HUMAN,tr|Q5PY61|Q5PY61_HUMAN,tr|F5H2Z3|F5H2Z3_HUMAN,tr|F5H2Z3|F5H2Z3_HUMAN,tr|M0R2S1|M0R2S1_HUMAN,tr|J3QS39|J3QS39_HUMAN,tr|J3QTR3|J3QTR3_HUMAN,tr|Q96C32|Q96C32_HUMAN,tr|Q96C32|Q96C32_HUMAN,tr|Q96C32|Q96C32_HUMAN,tr|Q96C32|Q96C32_HUMAN,tr|M0R1V7|M0R1V7_HUMAN,tr|F5H747|F5H747_HUMAN,tr|F5H747|F5H747_HUMAN,tr|F5GXK7|F5GXK7_HUMAN,tr|F5GXK7|F5GXK7_HUMAN,tr|M0R1M6|M0R1M6_HUMAN,tr|F5H6Q2|F5H6Q2_HUMAN,tr|F5H6Q2|F5H6Q2_HUMAN,tr|F5GZ39|F5GZ39_HUMAN,tr|J3QKN0|J3QKN0_HUMAN,tr|J3QKN0|J3QKN0_HUMAN,tr|F5H265|F5H265_HUMAN,tr|F5H265|F5H265_HUMAN,tr|A0A2R8Y422|A0A2R8Y422_HUMAN" 47 1540.7964 -1 112142 6312 3 1540.794362 514.6061 Ubiquitin-40S ribosomal protein S27a OS=Homo sapiens OX=9606 GN=RPS27A PE=1 SV=2 4.56 1600.6 - 3.18E+06 - - - -1.3487 - 2.343 0.44 - 362.7 1 2 1 -0.0021 13 0 0 0 0.00E+00 0.00E+00 - - - 5.7535 0.9997 221125_WJC_METTL3_EV_vs_WT_F08.06315.06315.3 0.000201 16/48 K.IQDKEGIPPDQQR.L "sp|P62979|RS27A_HUMAN,sp|P0CG48|UBC_HUMAN,sp|P0CG48|UBC_HUMAN,sp|P0CG48|UBC_HUMAN,sp|P0CG48|UBC_HUMAN,sp|P0CG48|UBC_HUMAN,sp|P0CG48|UBC_HUMAN,sp|P0CG48|UBC_HUMAN,sp|P0CG48|UBC_HUMAN,sp|P0CG48|UBC_HUMAN,sp|P0CG47|UBB_HUMAN,sp|P0CG47|UBB_HUMAN,sp|P0CG47|UBB_HUMAN,sp|P62987|RL40_HUMAN,tr|F5H388|F5H388_HUMAN,tr|F5H388|F5H388_HUMAN,tr|F5GYU3|F5GYU3_HUMAN,tr|F5GYU3|F5GYU3_HUMAN,tr|B4DV12|B4DV12_HUMAN,tr|B4DV12|B4DV12_HUMAN,tr|J3QSA3|J3QSA3_HUMAN,tr|Q5PY61|Q5PY61_HUMAN,tr|Q5PY61|Q5PY61_HUMAN,tr|Q5PY61|Q5PY61_HUMAN,tr|F5H2Z3|F5H2Z3_HUMAN,tr|F5H2Z3|F5H2Z3_HUMAN,tr|M0R2S1|M0R2S1_HUMAN,tr|J3QS39|J3QS39_HUMAN,tr|J3QTR3|J3QTR3_HUMAN,tr|Q96C32|Q96C32_HUMAN,tr|Q96C32|Q96C32_HUMAN,tr|Q96C32|Q96C32_HUMAN,tr|Q96C32|Q96C32_HUMAN,tr|M0R1V7|M0R1V7_HUMAN,tr|F5H747|F5H747_HUMAN,tr|F5H747|F5H747_HUMAN,tr|F5GXK7|F5GXK7_HUMAN,tr|F5GXK7|F5GXK7_HUMAN,tr|M0R1M6|M0R1M6_HUMAN,tr|F5H6Q2|F5H6Q2_HUMAN,tr|F5H6Q2|F5H6Q2_HUMAN,tr|F5GZ39|F5GZ39_HUMAN,tr|J3QKN0|J3QKN0_HUMAN,tr|J3QKN0|J3QKN0_HUMAN,tr|F5H265|F5H265_HUMAN,tr|F5H265|F5H265_HUMAN,tr|A0A2R8Y422|A0A2R8Y422_HUMAN" 47 1522.774 0.66 112143 6315 3 1522.772981 508.5986 Ubiquitin-40S ribosomal protein S27a OS=Homo sapiens OX=9606 GN=RPS27A PE=1 SV=2 4.56 1600.9 - 2.02E+06 - - - -0.6495 - 2.406 0.432 - 300.3 1 2 1 -0.001 13 0 0 0 2.69E+08 4.08E+08 - - - 5.7365 0.9998 221125_WJC_METTL3_EV_vs_WT_F08.06316.06316.2 2.99E-05 24-Oct K.ASSTSLTSTQPTK.T "sp|P35658|NU214_HUMAN,tr|A0A0A0MSW3|A0A0A0MSW3_HUMAN,tr|E9PKD2|E9PKD2_HUMAN,tr|B7ZAV2|B7ZAV2_HUMAN,tr|A0A494C1F2|A0A494C1F2_HUMAN,tr|H0Y837|H0Y837_HUMAN" 6 1307.6569 1.83 112144 6316 2 1307.655003 654.8357 Nuclear pore complex protein Nup214 OS=Homo sapiens OX=9606 GN=NUP214 PE=1 SV=2 8.8 1601.1 - 698097 - - - -1.4316 - 2.225 0.44 - 230.1 1 2 0 -0.0019 13 0 0 0 1.04E+09 5.69E+08 - - - 4.3429 1 221125_WJC_METTL3_EV_vs_WT_F08.06319.06319.2 1.50E-05 16/26 K.K[136.11]GPGEVAGTVTGQK[136.11].R "sp|Q86U44|MTA70_HUMAN,tr|F5H6D8|F5H6D8_HUMAN,tr|H0YFV6|H0YFV6_HUMAN,tr|B4DTN4|B4DTN4_HUMAN" 4 1343.738 0 112145 6319 2 1343.735801 672.8763 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 8.59 1601.5 - 1.79E+08 - - - -1.6209 - 3.415 0.523 - 591.3 1 2 0 -0.0022 14 0 0 0 1.76E+09 5.79E+11 - - - 5.9852 0.9998 221125_WJC_METTL3_EV_vs_WT_F08.06321.06321.3 0.00019 13/36 R.RQQEVETELK.M "sp|P08621|RU17_HUMAN,tr|M0QX04|M0QX04_HUMAN,tr|M0QYR1|M0QYR1_HUMAN" 3 1258.6517 2.13 112146 6321 3 1258.65017 420.5579 U1 small nuclear ribonucleoprotein 70 kDa OS=Homo sapiens OX=9606 GN=SNRNP70 PE=1 SV=2 4.79 1601.7 - 1.15E+06 - - - -1.2394 - 2.479 0.334 - 434.7 1 2 0 -0.0016 10 0 0 0 1.08E+08 5.09E+07 - - - 4.9147 0.9982 221125_WJC_METTL3_EV_vs_WT_F08.06323.06323.3 0.00466 Aug-32 K.SQDFYEKEK.L sp|Q8N183|NDUF2_HUMAN 1 1172.535 0.48 112148 6323 3 1172.53284 391.8523 NADH dehydrogenase [ubiquinone] 1 alpha subcomplex assembly factor 2 OS=Homo sapiens OX=9606 GN=NDUFAF2 PE=1 SV=1 4.68 1601.9 - 635872 - - - -1.8157 - 1.537 0.408 - 109.8 1 2 1 -0.0021 9 0 0 0 9.42E+07 1.95E+08 - - - 4.3836 0.9997 221125_WJC_METTL3_EV_vs_WT_F08.06328.06328.3 0.00139 13/40 K.SESPKEPEQLR.K "sp|P09651|ROA1_HUMAN,tr|F8W646|F8W646_HUMAN,tr|A0A7I2V3R8|A0A7I2V3R8_HUMAN,tr|F8VTQ5|F8VTQ5_HUMAN,tr|A0A7I2YQ85|A0A7I2YQ85_HUMAN,tr|F8W6I7|F8W6I7_HUMAN,tr|A0A7I2V2L6|A0A7I2V2L6_HUMAN,tr|A0A7I2V3W0|A0A7I2V3W0_HUMAN" 8 1298.6466 1.4 112150 6328 3 1298.644922 433.8895 Heterogeneous nuclear ribonucleoprotein A1 OS=Homo sapiens OX=9606 GN=HNRNPA1 PE=1 SV=5 4.78 1602.5 - 5.04E+07 - - - -1.326 - 2.8 0.404 - 317.7 1 2 1 -0.0017 11 0 0 0 6.69E+09 4.79E+09 - - - 5.9687 0.9997 221125_WJC_METTL3_EV_vs_WT_F08.06332.06332.2 0.000894 18-Nov R.KGESGQSWPR.L "sp|Q15185|TEBP_HUMAN,tr|B4DDC6|B4DDC6_HUMAN,tr|A0A087WYT3|A0A087WYT3_HUMAN" 3 1130.5469 0.96 112153 6332 2 1130.545101 566.2807 Prostaglandin E synthase 3 OS=Homo sapiens OX=9606 GN=PTGES3 PE=1 SV=1 8.75 1603.1 - 581951 - - - -1.5656 - 2.132 0.441 - 362.8 1 2 0 -0.0018 10 0 0 0 3.58E+07 3.72E+07 - - - 4.4109 0.9999 221125_WJC_METTL3_EV_vs_WT_F08.06335.06335.2 3.00E-05 18-Dec K.TENNDHINLK.V sp|P61956|SUMO2_HUMAN 1 1196.5786 0.99 112154 6335 2 1196.577948 599.2966 Small ubiquitin-related modifier 2 OS=Homo sapiens OX=9606 GN=SUMO2 PE=1 SV=3 5.29 1603.4 - 772106 - - - -0.5156 - 2.216 0.499 - 565.8 1 2 0 -0.0006 10 0 0 0 2.23E+07 2.26E+07 - - - 4.9475 0.9999 221125_WJC_METTL3_EV_vs_WT_F08.06339.06339.2 4.37E-06 24-Dec K.SQGSGNEAEPLGK.G "sp|Q9NUQ6|SPS2L_HUMAN,tr|B8ZZZ7|B8ZZZ7_HUMAN" 2 1272.5946 1.9 112156 6339 2 1272.595251 637.3046 SPATS2-like protein OS=Homo sapiens OX=9606 GN=SPATS2L PE=1 SV=2 4.53 1603.9 - 1.19E+06 - - - 0.5045 - 2.393 0.521 - 443.2 1 2 0 0.0006 13 0 0 0 3.32E+07 1.75E+07 - - - 5.1283 0.9994 221125_WJC_METTL3_EV_vs_WT_F08.06346.06346.2 0.00845 14/24 K.ASSTSLTSTQPTK[136.11].T "sp|P35658|NU214_HUMAN,tr|A0A0A0MSW3|A0A0A0MSW3_HUMAN,tr|E9PKD2|E9PKD2_HUMAN,tr|B7ZAV2|B7ZAV2_HUMAN,tr|A0A494C1F2|A0A494C1F2_HUMAN,tr|H0Y837|H0Y837_HUMAN" 6 1315.6711 1.92 112159 6346 2 1315.66749 658.8428 Nuclear pore complex protein Nup214 OS=Homo sapiens OX=9606 GN=NUP214 PE=1 SV=2 8.8 1604.8 - 4.05E+06 - - - -2.7248 - 2.553 0.407 - 633.8 1 2 0 -0.0036 13 0 0 0 1.04E+09 5.42E+08 - - - 4.4515 1 221125_WJC_METTL3_EV_vs_WT_F08.06361.06361.3 5.54E-08 14/52 K.K[136.11]GPGEVAGTVTGQK[136.11].R "sp|Q86U44|MTA70_HUMAN,tr|F5H6D8|F5H6D8_HUMAN,tr|H0YFV6|H0YFV6_HUMAN,tr|B4DTN4|B4DTN4_HUMAN" 4 1343.738 0 112166 6361 3 1343.738117 448.9199 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 8.59 1606.7 - 1.22E+09 - - - 0.1027 - 2.919 0.551 - 325.6 1 2 0 0.0001 14 0 0 0 1.08E+08 1.02E+12 - - - 7.5299 0.9998 221125_WJC_METTL3_EV_vs_WT_F08.06366.06366.3 0.000218 Dec-32 K.SQDFYEKEK.L sp|Q8N183|NDUF2_HUMAN 1 1172.535 0.82 112169 6366 3 1172.533253 391.8523 NADH dehydrogenase [ubiquinone] 1 alpha subcomplex assembly factor 2 OS=Homo sapiens OX=9606 GN=NDUFAF2 PE=1 SV=1 4.68 1607.3 - 2.66E+06 - - - -1.4635 - 2.053 0.486 - 239.4 1 2 1 -0.0017 9 0 0 0 9.32E+07 1.14E+08 - - - 6.1258 0.794 221125_WJC_METTL3_EV_vs_WT_F08.06382.06382.3 0.0297 Oct-32 W.SQHYHQGYY.- "sp|Q00839|HNRPU_HUMAN,tr|A0A1W2PPL4|A0A1W2PPL4_HUMAN,tr|A0A087WVI9|A0A087WVI9_HUMAN,tr|Q5RI18|Q5RI18_HUMAN,tr|A0A1W2PP35|A0A1W2PP35_HUMAN,tr|A0A1W2PPH7|A0A1W2PPH7_HUMAN,tr|A0A1W2PQD4|A0A1W2PQD4_HUMAN,tr|A0A1X7SBS1|A0A1X7SBS1_HUMAN" 8 1181.489 - 112173 6382 3 1181.486859 394.837 Heterogeneous nuclear ribonucleoprotein U OS=Homo sapiens OX=9606 GN=HNRNPU PE=1 SV=6 6.66 1609.7 - 2.41E+06 - - - -1.8299 - 1.335 0.323 - 85.1 1 1 0 -0.0022 9 0 0 0 - - - - - 3.0113 1 221125_WJC_METTL3_EV_vs_WT_F08.06385.06385.2 2.29E-06 14/24 R.FSSSSGYGGGSSR.V sp|P35527|K1C9_HUMAN 1 1234.5214 999 112174 6385 2 1234.518309 618.268 "Keratin, type I cytoskeletal 9 OS=Homo sapiens OX=9606 GN=KRT9 PE=1 SV=3" 8.75 1610.1 - 1.80E+06 - - - -2.5394 - 2.662 0.638 - 586.1 1 2 0 -0.0031 13 0 0 0 9.54E+09 0.00E+00 - - - 6.2651 1 221125_WJC_METTL3_EV_vs_WT_F08.06391.06391.2 1.72E-06 21/26 K.KGPGEVAGTVTGQK.R "sp|Q86U44|MTA70_HUMAN,tr|F5H6D8|F5H6D8_HUMAN,tr|H0YFV6|H0YFV6_HUMAN,tr|B4DTN4|B4DTN4_HUMAN" 4 1327.7096 0 112178 6391 2 1327.70768 664.8621 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 8.59 1610.8 - 2.14E+06 - - - -1.4303 - 3.523 0.597 - 1119.9 1 2 0 -0.0019 14 0 0 0 1.52E+09 5.05E+11 - - - 6.61 0.9934 221125_WJC_METTL3_EV_vs_WT_F08.06402.06402.2 0.0595 16-Oct W.SQHYHQGYY.- "sp|Q00839|HNRPU_HUMAN,tr|A0A1W2PPL4|A0A1W2PPL4_HUMAN,tr|A0A087WVI9|A0A087WVI9_HUMAN,tr|Q5RI18|Q5RI18_HUMAN,tr|A0A1W2PP35|A0A1W2PP35_HUMAN,tr|A0A1W2PPH7|A0A1W2PPH7_HUMAN,tr|A0A1W2PQD4|A0A1W2PQD4_HUMAN,tr|A0A1X7SBS1|A0A1X7SBS1_HUMAN" 8 1181.489 - 112183 6402 2 1181.488453 591.7518 Heterogeneous nuclear ribonucleoprotein U OS=Homo sapiens OX=9606 GN=HNRNPU PE=1 SV=6 6.66 1612.2 - 897261 - - - -0.4807 - 2.137 0.52 - 287.6 1 1 0 -0.0006 9 0 0 0 - - - - - 5.0785 1 221125_WJC_METTL3_EV_vs_WT_F08.06440.06440.3 3.49E-05 13/40 K.EHVGTDQFGNK.Y "sp|Q8N183|NDUF2_HUMAN,tr|A0A7I2V3X5|A0A7I2V3X5_HUMAN,tr|D6RA56|D6RA56_HUMAN,tr|A0A7I2YQX2|A0A7I2YQX2_HUMAN,tr|A0A7I2V4Z7|A0A7I2V4Z7_HUMAN" 5 1230.5629 1.54 112193 6440 3 1230.560125 411.1949 NADH dehydrogenase [ubiquinone] 1 alpha subcomplex assembly factor 2 OS=Homo sapiens OX=9606 GN=NDUFAF2 PE=1 SV=1 5.32 1617.6 - 5.06E+06 - - - -2.2673 - 2.435 0.563 - 305.7 1 2 0 -0.0028 11 0 0 0 4.34E+08 2.83E+08 - - - 7.3443 0.8764 221125_WJC_METTL3_EV_vs_WT_F08.06466.06466.2 0.0231 16-Aug E.VAGTVTGQK[136.11].R "sp|Q86U44|MTA70_HUMAN,tr|F5H6D8|F5H6D8_HUMAN,tr|H0YFV6|H0YFV6_HUMAN,tr|B4DTN4|B4DTN4_HUMAN" 4 867.4905 0.03 112200 6466 2 867.487655 434.7525 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 8.72 1621.2 - 3.87E+06 - - - -3.3153 - 1.715 0.354 - 141.6 1 1 0 -0.0029 9 0 0 0 3.19E+07 1.21E+09 - - - 3.2153 1 221125_WJC_METTL3_EV_vs_WT_F08.06472.06472.3 1.32E-05 13/52 K.K[136.11]GPGEVAGTVTGQK.R "sp|Q86U44|MTA70_HUMAN,tr|F5H6D8|F5H6D8_HUMAN,tr|H0YFV6|H0YFV6_HUMAN,tr|B4DTN4|B4DTN4_HUMAN" 4 1335.7238 - 112203 6472 3 1335.722948 446.2485 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 8.59 1622 - 1.52E+08 - - - -0.6221 - 2.51 0.442 - 316.2 1 2 0 -0.0008 14 0 0 0 - - - - - 5.9133 0.9098 221125_WJC_METTL3_EV_vs_WT_F08.06514.06514.2 0.0146 14-Aug V.AGTVTGQK[136.11].R "sp|Q86U44|MTA70_HUMAN,tr|F5H6D8|F5H6D8_HUMAN,tr|H0YFV6|H0YFV6_HUMAN,tr|B4DTN4|B4DTN4_HUMAN" 4 768.4221 0.15 112211 6514 2 768.420224 385.2183 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 8.8 1628.2 - 1.79E+07 - - - -2.4648 - 1.937 0.257 - 334.7 1 1 0 -0.0019 8 0 0 0 6.74E+08 4.38E+09 - - - 2.9326 1 221125_WJC_METTL3_EV_vs_WT_F08.06528.06528.2 2.54E-05 17/26 K.KGPGEVAGTVTGQK[136.11].R "sp|Q86U44|MTA70_HUMAN,tr|F5H6D8|F5H6D8_HUMAN,tr|H0YFV6|H0YFV6_HUMAN,tr|B4DTN4|B4DTN4_HUMAN" 4 1335.7238 - 112215 6528 2 1335.721492 668.8692 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 8.59 1630.2 - 1.01E+08 - - - -1.7122 - 3.261 0.516 - 554.7 1 2 0 -0.0023 14 0 0 0 - - - - - 5.8177 1 221125_WJC_METTL3_EV_vs_WT_F08.06539.06539.2 7.83E-07 19/26 K.K[136.11]GPGEVAGTVTGQK[136.11].R "sp|Q86U44|MTA70_HUMAN,tr|F5H6D8|F5H6D8_HUMAN,tr|H0YFV6|H0YFV6_HUMAN,tr|B4DTN4|B4DTN4_HUMAN" 4 1343.738 0 112218 6539 2 1343.735533 672.8763 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 8.59 1631.7 - 2.84E+09 - - - -1.8203 - 3.46 0.598 - 996.6 1 2 0 -0.0024 14 0 0 0 1.76E+09 5.79E+11 - - - 6.572 1 221125_WJC_METTL3_EV_vs_WT_F08.06559.06559.2 4.37E-07 13/22 K.DTSSSTVVSTQR.S "sp|P31483|TIA1_HUMAN,tr|F8W8I6|F8W8I6_HUMAN,tr|E5RG67|E5RG67_HUMAN,tr|E5RGV5|E5RGV5_HUMAN" 4 1266.6052 2.25 112220 6559 2 1266.603298 634.3099 Nucleolysin TIA-1 isoform p40 OS=Homo sapiens OX=9606 GN=TIA1 PE=1 SV=3 5.84 1634.9 - 3.87E+06 - - - -1.4803 - 2.644 0.575 - 778.6 1 2 0 -0.0019 12 0 0 0 2.01E+08 8.93E+07 - - - 5.8456 0.9958 221125_WJC_METTL3_EV_vs_WT_F08.06563.06563.3 0.0015 14/36 K.NKQPTPVNIR.A "sp|Q9Y3Y2|CHTOP_HUMAN,tr|A0A087X1B7|A0A087X1B7_HUMAN,tr|X6R700|X6R700_HUMAN" 3 1165.6568 1.6 112221 6563 3 1165.653312 389.5595 Chromatin target of PRMT1 protein OS=Homo sapiens OX=9606 GN=CHTOP PE=1 SV=2 11 1635.4 - 4.89E+06 - - - -2.9537 - 2.495 0.283 - 318.6 1 2 1 -0.0034 10 0 0 0 1.27E+09 7.94E+08 - - - 4.3643 0.991 221125_WJC_METTL3_EV_vs_WT_F08.06564.06564.3 0.00173 Nov-36 K.NK[136.11]QPTPVNIR[166.11].A "sp|Q9Y3Y2|CHTOP_HUMAN,tr|A0A087X1B7|A0A087X1B7_HUMAN,tr|X6R700|X6R700_HUMAN" 3 1183.6792 1.6 112222 6564 3 1183.676327 395.567 Chromatin target of PRMT1 protein OS=Homo sapiens OX=9606 GN=CHTOP PE=1 SV=2 11 1635.5 - 4.70E+06 - - - -2.4483 - 2.133 0.245 - 209.5 1 2 1 -0.0029 10 0 0 0 1.27E+09 7.94E+08 - - - 3.483 0.9994 221125_WJC_METTL3_EV_vs_WT_F08.06565.06565.2 0.00032 14/24 K.GPGEVAGTVTGQK[136.11].R "sp|Q86U44|MTA70_HUMAN,tr|F5H6D8|F5H6D8_HUMAN,tr|H0YFV6|H0YFV6_HUMAN,tr|B4DTN4|B4DTN4_HUMAN" 4 1207.6288 0 112223 6565 2 1207.624559 604.8217 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 6 1635.6 - 0 - - - -3.5251 - 2.709 0.535 - 875 1 2 0 -0.0043 13 0 0 0 7.40E+05 2.17E+08 - - - 5.5489 1 221125_WJC_METTL3_EV_vs_WT_F08.06577.06577.3 1.83E-07 16/52 K.K[136.11]GPGEVAGTVTGQK[136.11].R "sp|Q86U44|MTA70_HUMAN,tr|F5H6D8|F5H6D8_HUMAN,tr|H0YFV6|H0YFV6_HUMAN,tr|B4DTN4|B4DTN4_HUMAN" 4 1343.738 0 112229 6577 3 1343.736705 448.9199 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 8.59 1637 - 4.19E+09 - - - -0.9481 - 3.048 0.551 - 400.8 1 2 0 -0.0013 14 0 0 0 1.08E+08 1.02E+12 - - - 7.6445 0.9999 221125_WJC_METTL3_EV_vs_WT_F08.06583.06583.2 2.31E-05 16-Sep K.SYSEDDIHR.S "sp|Q9Y5A9|YTHD2_HUMAN,sp|Q9BYJ9|YTHD1_HUMAN,sp|Q7Z739|YTHD3_HUMAN,tr|A0A087X0Q1|A0A087X0Q1_HUMAN,tr|A0A024R7W5|A0A024R7W5_HUMAN,tr|A0A087WY31|A0A087WY31_HUMAN" 6 1120.4785 1.41 112230 6583 2 1120.477531 561.2465 YTH domain-containing family protein 2 OS=Homo sapiens OX=9606 GN=YTHDF2 PE=1 SV=2 4.53 1637.9 - 6.60E+06 - - - -0.8791 - 1.89 0.651 - 255 1 2 0 -0.001 9 0 0 0 9.25E+08 6.54E+08 - - - 5.6906 1 221125_WJC_METTL3_EV_vs_WT_F08.06585.06585.2 7.94E-07 16-Oct K.SYSEDDIHR[166.11].S "sp|Q9Y5A9|YTHD2_HUMAN,sp|Q9BYJ9|YTHD1_HUMAN,sp|Q7Z739|YTHD3_HUMAN,tr|A0A087X0Q1|A0A087X0Q1_HUMAN,tr|A0A024R7W5|A0A024R7W5_HUMAN,tr|A0A087WY31|A0A087WY31_HUMAN" 6 1130.4868 1.41 112232 6585 2 1130.48471 566.2507 YTH domain-containing family protein 2 OS=Homo sapiens OX=9606 GN=YTHDF2 PE=1 SV=2 4.53 1638 - 4.60E+06 - - - -1.8364 - 2.076 0.627 - 289 1 2 0 -0.0021 9 0 0 0 9.25E+08 6.54E+08 - - - 5.7846 0.9777 221125_WJC_METTL3_EV_vs_WT_F08.06586.06586.2 0.0323 18-Nov K.NKQPTPVNIR.A "sp|Q9Y3Y2|CHTOP_HUMAN,tr|A0A087X1B7|A0A087X1B7_HUMAN,tr|X6R700|X6R700_HUMAN" 3 1165.6568 1.94 112233 6586 2 1165.654139 583.8357 Chromatin target of PRMT1 protein OS=Homo sapiens OX=9606 GN=CHTOP PE=1 SV=2 11 1638.1 - 4.53E+06 - - - -2.2442 - 1.73 0.272 - 383.9 1 2 1 -0.0026 10 0 0 0 4.12E+08 2.12E+08 - - - 2.5791 0.9934 221125_WJC_METTL3_EV_vs_WT_F08.06597.06597.2 0.000295 18-Nov K.NK[136.11]QPTPVNIR[166.11].A "sp|Q9Y3Y2|CHTOP_HUMAN,tr|A0A087X1B7|A0A087X1B7_HUMAN,tr|X6R700|X6R700_HUMAN" 3 1183.6792 1.94 112235 6597 2 1183.676294 592.8469 Chromatin target of PRMT1 protein OS=Homo sapiens OX=9606 GN=CHTOP PE=1 SV=2 11 1639.8 - 4.86E+06 - - - -2.4762 - 1.977 0.429 - 372.7 1 2 1 -0.0029 10 0 0 0 4.12E+08 2.12E+08 - - - 4.1112 0.9995 221125_WJC_METTL3_EV_vs_WT_F08.06609.06609.3 7.99E-05 Oct-40 R.GIDSSYR[166.11]PSQK[136.11].D "sp|Q96CB8|INT12_HUMAN,tr|C9J0M6|C9J0M6_HUMAN,tr|A0A087WXN4|A0A087WXN4_HUMAN,tr|A0A1B0GX90|A0A1B0GX90_HUMAN,tr|E9PGI3|E9PGI3_HUMAN,tr|C9JDP3|C9JDP3_HUMAN" 6 1254.6323 0.87 112239 6609 3 1254.628416 419.2181 Integrator complex subunit 12 OS=Homo sapiens OX=9606 GN=INTS12 PE=1 SV=1 8.59 1641.4 - 2.05E+06 - - - -3.1236 - 1.894 0.413 - 85.1 1 2 0 -0.0039 11 0 0 0 1.47E+08 1.69E+08 - - - 4.9579 0.7642 221125_WJC_METTL3_EV_vs_WT_F08.06624.06624.2 1.59 22-Aug R.QTGAEGTR[166.11]GPAK[136.11].A sp|O43638|FOXS1_HUMAN 1 1189.617 0 112242 6624 2 1189.616372 595.8158 Forkhead box protein S1 OS=Homo sapiens OX=9606 GN=FOXS1 PE=2 SV=2 8.75 1643.6 - 5.55E+06 - - - -0.5439 - 1.406 0.036 - 137 3 2 1 -0.0006 12 0 0 0 2.43E+06 1.41E+09 - - - -0.0099 1 221125_WJC_METTL3_EV_vs_WT_F08.06625.06625.2 3.57E-07 24/26 K.KGPGEVAGTVTGQK.R "sp|Q86U44|MTA70_HUMAN,tr|F5H6D8|F5H6D8_HUMAN,tr|H0YFV6|H0YFV6_HUMAN,tr|B4DTN4|B4DTN4_HUMAN" 4 1327.7096 0 112243 6625 2 1327.707719 664.8621 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 8.59 1643.7 - 5.05E+06 - - - -1.4009 - 3.782 0.574 - 1401.1 1 2 0 -0.0019 14 0 0 0 1.69E+09 5.59E+11 - - - 6.6182 0.9884 221125_WJC_METTL3_EV_vs_WT_F08.06627.06627.2 2.28E-05 14-Sep S.YSEDDIHR.S "sp|Q9Y5A9|YTHD2_HUMAN,sp|Q9BYJ9|YTHD1_HUMAN,sp|Q7Z739|YTHD3_HUMAN,tr|A0A087X0Q1|A0A087X0Q1_HUMAN,tr|A0A024R7W5|A0A024R7W5_HUMAN,tr|A0A087WY31|A0A087WY31_HUMAN" 6 1033.4465 2.64 112245 6627 2 1033.444916 517.7305 YTH domain-containing family protein 2 OS=Homo sapiens OX=9606 GN=YTHDF2 PE=1 SV=2 4.54 1643.8 - 2.16E+06 - - - -1.5211 - 1.735 0.555 - 259.9 1 1 0 -0.0016 8 0 0 0 5.97E+07 2.26E+07 - - - 4.8015 0.9997 221125_WJC_METTL3_EV_vs_WT_F08.06631.06631.3 0.000826 17/48 K.IQDK[136.11]EGIPPDQQR[166.11].L "sp|P62979|RS27A_HUMAN,sp|P0CG48|UBC_HUMAN,sp|P0CG48|UBC_HUMAN,sp|P0CG48|UBC_HUMAN,sp|P0CG48|UBC_HUMAN,sp|P0CG48|UBC_HUMAN,sp|P0CG48|UBC_HUMAN,sp|P0CG48|UBC_HUMAN,sp|P0CG48|UBC_HUMAN,sp|P0CG48|UBC_HUMAN,sp|P0CG47|UBB_HUMAN,sp|P0CG47|UBB_HUMAN,sp|P0CG47|UBB_HUMAN,sp|P62987|RL40_HUMAN,tr|F5H388|F5H388_HUMAN,tr|F5H388|F5H388_HUMAN,tr|F5GYU3|F5GYU3_HUMAN,tr|F5GYU3|F5GYU3_HUMAN,tr|B4DV12|B4DV12_HUMAN,tr|B4DV12|B4DV12_HUMAN,tr|J3QSA3|J3QSA3_HUMAN,tr|Q5PY61|Q5PY61_HUMAN,tr|Q5PY61|Q5PY61_HUMAN,tr|Q5PY61|Q5PY61_HUMAN,tr|F5H2Z3|F5H2Z3_HUMAN,tr|F5H2Z3|F5H2Z3_HUMAN,tr|M0R2S1|M0R2S1_HUMAN,tr|J3QS39|J3QS39_HUMAN,tr|J3QTR3|J3QTR3_HUMAN,tr|Q96C32|Q96C32_HUMAN,tr|Q96C32|Q96C32_HUMAN,tr|Q96C32|Q96C32_HUMAN,tr|Q96C32|Q96C32_HUMAN,tr|M0R1V7|M0R1V7_HUMAN,tr|F5H747|F5H747_HUMAN,tr|F5H747|F5H747_HUMAN,tr|F5GXK7|F5GXK7_HUMAN,tr|F5GXK7|F5GXK7_HUMAN,tr|M0R1M6|M0R1M6_HUMAN,tr|F5H6Q2|F5H6Q2_HUMAN,tr|F5H6Q2|F5H6Q2_HUMAN,tr|F5GZ39|F5GZ39_HUMAN,tr|J3QKN0|J3QKN0_HUMAN,tr|J3QKN0|J3QKN0_HUMAN,tr|F5H265|F5H265_HUMAN,tr|F5H265|F5H265_HUMAN,tr|A0A2R8Y422|A0A2R8Y422_HUMAN" 47 1540.7964 0.71 112246 6631 3 1540.794668 514.6061 Ubiquitin-40S ribosomal protein S27a OS=Homo sapiens OX=9606 GN=RPS27A PE=1 SV=2 4.56 1644.4 - 2.57E+06 - - - -1.1501 - 2.689 0.413 - 422.9 1 2 1 -0.0018 13 0 0 0 1.11E+08 1.55E+08 - - - 5.826 0.9998 221125_WJC_METTL3_EV_vs_WT_F08.06638.06638.3 0.00111 16/48 K.IQDKEGIPPDQQR.L "sp|P62979|RS27A_HUMAN,sp|P0CG48|UBC_HUMAN,sp|P0CG48|UBC_HUMAN,sp|P0CG48|UBC_HUMAN,sp|P0CG48|UBC_HUMAN,sp|P0CG48|UBC_HUMAN,sp|P0CG48|UBC_HUMAN,sp|P0CG48|UBC_HUMAN,sp|P0CG48|UBC_HUMAN,sp|P0CG48|UBC_HUMAN,sp|P0CG47|UBB_HUMAN,sp|P0CG47|UBB_HUMAN,sp|P0CG47|UBB_HUMAN,sp|P62987|RL40_HUMAN,tr|F5H388|F5H388_HUMAN,tr|F5H388|F5H388_HUMAN,tr|F5GYU3|F5GYU3_HUMAN,tr|F5GYU3|F5GYU3_HUMAN,tr|B4DV12|B4DV12_HUMAN,tr|B4DV12|B4DV12_HUMAN,tr|J3QSA3|J3QSA3_HUMAN,tr|Q5PY61|Q5PY61_HUMAN,tr|Q5PY61|Q5PY61_HUMAN,tr|Q5PY61|Q5PY61_HUMAN,tr|F5H2Z3|F5H2Z3_HUMAN,tr|F5H2Z3|F5H2Z3_HUMAN,tr|M0R2S1|M0R2S1_HUMAN,tr|J3QS39|J3QS39_HUMAN,tr|J3QTR3|J3QTR3_HUMAN,tr|Q96C32|Q96C32_HUMAN,tr|Q96C32|Q96C32_HUMAN,tr|Q96C32|Q96C32_HUMAN,tr|Q96C32|Q96C32_HUMAN,tr|M0R1V7|M0R1V7_HUMAN,tr|F5H747|F5H747_HUMAN,tr|F5H747|F5H747_HUMAN,tr|F5GXK7|F5GXK7_HUMAN,tr|F5GXK7|F5GXK7_HUMAN,tr|M0R1M6|M0R1M6_HUMAN,tr|F5H6Q2|F5H6Q2_HUMAN,tr|F5H6Q2|F5H6Q2_HUMAN,tr|F5GZ39|F5GZ39_HUMAN,tr|J3QKN0|J3QKN0_HUMAN,tr|J3QKN0|J3QKN0_HUMAN,tr|F5H265|F5H265_HUMAN,tr|F5H265|F5H265_HUMAN,tr|A0A2R8Y422|A0A2R8Y422_HUMAN" 47 1522.774 0.71 112249 6638 3 1522.774007 508.5986 Ubiquitin-40S ribosomal protein S27a OS=Homo sapiens OX=9606 GN=RPS27A PE=1 SV=2 4.56 1645.3 - 2.11E+06 - - - 0.0243 - 2.699 0.435 - 377.9 1 2 1 0 13 0 0 0 3.56E+08 4.98E+08 - - - 6.0818 1 221125_WJC_METTL3_EV_vs_WT_F08.06656.06656.3 0.039 31/68 K.GTGGASAEGGPTGLAHGR.L sp|Q96F45|ZN503_HUMAN 1 1551.739 1.54 112255 6656 3 1551.735205 518.2536 Zinc finger protein 503 OS=Homo sapiens OX=9606 GN=ZNF503 PE=1 SV=1 6.75 1647.6 - 1.94E+06 - - - -2.434 - 4.658 0.623 - 1849.6 1 2 0 -0.0038 18 0 0 0 5.40E+08 3.51E+08 - - - 9.316 0.8677 221125_WJC_METTL3_EV_vs_WT_F08.06665.06665.3 0.108 Sep-40 R.STSHK[136.11]PDEIYG.M sp|Q86U44|MTA70_HUMAN 1 1240.5815 0.03 112258 6665 3 1240.578011 414.5345 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 5.3 1648.7 - 2.07E+06 - - - -2.8374 - 1.967 0.311 - 43.9 1 1 0 -0.0035 11 0 0 0 1.88E+06 6.37E+07 - - - 3.9282 0.9836 221125_WJC_METTL3_EV_vs_WT_F08.06666.06666.3 0.000953 15/44 R.QMGQPC[160.03]DAYQKR.L sp|P15924|DESP_HUMAN 1 1480.6551 999 112259 6666 3 1481.651694 494.559 Desmoplakin OS=Homo sapiens OX=9606 GN=DSP PE=1 SV=3 8.2 1648.9 - 1.35E+06 - - - 673.0642 - 2.671 0.444 - 413 1 2 0 0.9966 12 0 0 0 4.92E+07 0.00E+00 - - - 5.9373 1 221125_WJC_METTL3_EV_vs_WT_F08.06669.06669.3 1.73E-05 25/68 K.GTGGASAEGGPTGLAHGR[166.11].L sp|Q96F45|ZN503_HUMAN 1 1561.7473 1.61 112260 6669 3 1561.744735 521.5897 Zinc finger protein 503 OS=Homo sapiens OX=9606 GN=ZNF503 PE=1 SV=1 6.75 1649.2 - 3.24E+06 - - - -1.6117 - 3.721 0.477 - 647.2 1 2 0 -0.0025 18 0 0 0 4.84E+08 3.00E+08 - - - 7.1294 0.9999 221125_WJC_METTL3_EV_vs_WT_F08.06674.06674.3 0.000193 16/44 R.AFHNEAQVNPER[166.11].K "sp|P17987|TCPA_HUMAN,tr|F5H282|F5H282_HUMAN,tr|E7EQR6|E7EQR6_HUMAN" 3 1420.6723 0.53 112263 6674 3 1420.671495 474.5647 T-complex protein 1 subunit alpha OS=Homo sapiens OX=9606 GN=TCP1 PE=1 SV=1 5.4 1649.8 - 2.68E+06 - - - -0.5638 - 3.244 0.348 - 533.8 1 2 0 -0.0008 12 0 0 0 3.43E+08 6.46E+08 - - - 5.6816 1 221125_WJC_METTL3_EV_vs_WT_F08.06678.06678.3 1.19E-09 19/52 K.C[160.03]VAC[160.03]ETPKPGTC[160.03]VK.R sp|P49790|NU153_HUMAN 1 1605.7313 1.28 112264 6678 3 1605.723699 536.251 Nuclear pore complex protein Nup153 OS=Homo sapiens OX=9606 GN=NUP153 PE=1 SV=2 7.95 1650.4 - 1.74E+06 - - - -4.7461 - 2.89 0.65 - 327.5 1 2 0 -0.0076 14 0 0 0 1.05E+08 8.17E+07 - - - 8.6051 0.9998 221125_WJC_METTL3_EV_vs_WT_F08.06680.06680.2 1.42E-05 20-Oct R.C[160.03]EMEQQNQEYK.L "sp|Q04695|K1C17_HUMAN,sp|P02533|K1C14_HUMAN,tr|A0A3B3IS58|A0A3B3IS58_HUMAN,tr|F5GWP8|F5GWP8_HUMAN" 4 1485.5864 999 112265 6680 2 1485.583963 743.8005 "Keratin, type I cytoskeletal 17 OS=Homo sapiens OX=9606 GN=KRT17 PE=1 SV=2" 4.25 1650.6 - 1.45E+06 - - - -1.66 - 2.123 0.602 - 261.1 1 2 0 -0.0025 11 0 0 0 8.14E+07 0.00E+00 - - - 5.5232 1 221125_WJC_METTL3_EV_vs_WT_F08.06682.06682.2 9.83E-10 26/42 R.AALAATGAASGGGGGGGGAGSR.S sp|A6NKD9|CC85C_HUMAN 1 1629.7819 8 112266 6682 2 1629.781729 815.8982 Coiled-coil domain-containing protein 85C OS=Homo sapiens OX=9606 GN=CCDC85C PE=1 SV=1 9.79 1650.8 - 1.53E+06 - - - -0.1104 - 4.675 0.7 - 2047.3 1 2 0 -0.0002 22 0 0 0 5.29E+07 6.61E+06 - - - 8.0028 0.833 221125_WJC_METTL3_EV_vs_WT_F08.06685.06685.3 0.00961 13/56 K.ATHDGAPELGAGGTR.Q "sp|Q9BXW7|HDHD5_HUMAN,tr|A8MYZ9|A8MYZ9_HUMAN" 2 1408.6695 5.88 112268 6685 3 1409.678171 470.5638 Haloacid dehalogenase-like hydrolase domain-containing 5 OS=Homo sapiens OX=9606 GN=HDHD5 PE=1 SV=1 5.32 1651.1 - 3.31E+06 - - - 716.0416 - 1.933 0.297 - 173.2 1 2 0 1.0087 15 0 0 0 2.69E+08 4.58E+07 - - - 3.2916 0.9999 221125_WJC_METTL3_EV_vs_WT_F08.06693.06693.3 0.000161 Nov-52 K.KGPGEVAGTVTGQK[136.11].R "sp|Q86U44|MTA70_HUMAN,tr|F5H6D8|F5H6D8_HUMAN,tr|H0YFV6|H0YFV6_HUMAN,tr|B4DTN4|B4DTN4_HUMAN" 4 1335.7238 - 112270 6693 3 1335.723676 446.2485 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 8.59 1652.2 - 7.46E+07 - - - -0.0771 - 2.418 0.412 - 224.8 1 2 0 -0.0001 14 0 0 0 - - - - - 5.4798 0.9701 221125_WJC_METTL3_EV_vs_WT_F08.06700.06700.2 0.105 16-Oct E.VAGTVTGQK[136.11].R "sp|Q86U44|MTA70_HUMAN,tr|F5H6D8|F5H6D8_HUMAN,tr|H0YFV6|H0YFV6_HUMAN,tr|B4DTN4|B4DTN4_HUMAN" 4 867.4905 0.03 112273 6700 2 867.489469 434.7525 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 8.72 1653 - 4.08E+06 - - - -1.2242 - 1.84 0.337 - 229.2 1 1 0 -0.0011 9 0 0 0 2.01E+07 7.31E+08 - - - 3.2938 1 221125_WJC_METTL3_EV_vs_WT_F08.06707.06707.3 4.05E-05 18/44 R.AFHNEAQVNPER.K "sp|P17987|TCPA_HUMAN,tr|F5H282|F5H282_HUMAN,tr|E7EQR6|E7EQR6_HUMAN" 3 1410.664 0.53 112276 6707 3 1410.660238 471.2286 T-complex protein 1 subunit alpha OS=Homo sapiens OX=9606 GN=TCP1 PE=1 SV=1 5.4 1653.9 - 3.12E+06 - - - -2.6853 - 3.493 0.511 - 665.3 1 2 0 -0.0038 12 0 0 0 3.46E+08 6.46E+08 - - - 7.703 0.9978 221125_WJC_METTL3_EV_vs_WT_F08.06723.06723.3 0.000277 Oct-36 R.K[136.11]AEFEEQNVR[166.11].K "sp|Q9UFW8|CGBP1_HUMAN,tr|C9JUJ0|C9JUJ0_HUMAN" 2 1266.6323 0.18 112280 6723 3 1266.626787 423.2181 CGG triplet repeat-binding protein 1 OS=Homo sapiens OX=9606 GN=CGGBP1 PE=1 SV=2 4.79 1656.2 - 624383 - - - -4.3801 - 1.898 0.367 - 168.6 1 2 0 -0.0055 10 0 0 0 4.02E+07 2.18E+08 - - - 4.5016 1 221125_WJC_METTL3_EV_vs_WT_F08.06730.06730.2 4.78E-08 13/22 R.AFHNEAQVNPER[166.11].K "sp|P17987|TCPA_HUMAN,tr|F5H282|F5H282_HUMAN,tr|E7EQR6|E7EQR6_HUMAN" 3 1420.6723 0.49 112284 6730 2 1420.676696 711.3434 T-complex protein 1 subunit alpha OS=Homo sapiens OX=9606 GN=TCP1 PE=1 SV=1 5.4 1657 - 1.16E+06 - - - 3.0971 - 2.669 0.62 - 551.3 1 2 0 0.0044 12 0 0 0 1.88E+07 3.85E+07 - - - 6.202 0.9995 221125_WJC_METTL3_EV_vs_WT_F08.06731.06731.3 0.000427 Nov-36 R.NTEEEGLKYK.S "sp|Q9NYF8|BCLF1_HUMAN,tr|E9PKI6|E9PKI6_HUMAN,tr|A0A1W2PQ43|A0A1W2PQ43_HUMAN,tr|E9PK91|E9PK91_HUMAN,tr|E9PK09|E9PK09_HUMAN,tr|E9PQN2|E9PQN2_HUMAN" 6 1209.5877 2.08 112285 6731 3 1209.586004 404.2032 Bcl-2-associated transcription factor 1 OS=Homo sapiens OX=9606 GN=BCLAF1 PE=1 SV=2 4.79 1657 - 7.81E+06 - - - -1.4294 - 1.94 0.428 - 194.3 1 2 1 -0.0017 10 0 0 0 3.48E+08 1.68E+08 - - - 5.2466 0.9986 221125_WJC_METTL3_EV_vs_WT_F08.06736.06736.3 0.0577 15/44 R.QTEEQVNDLKER.L sp|P12270|TPR_HUMAN 1 1487.7216 2.6 112288 6736 3 1487.716782 496.9145 Nucleoprotein TPR OS=Homo sapiens OX=9606 GN=TPR PE=1 SV=3 4.41 1657.5 - 907541 - - - -3.2385 - 2.743 0.383 - 472 1 2 1 -0.0048 12 0 0 0 8.33E+07 3.20E+07 - - - 5.6057 0.9914 221125_WJC_METTL3_EV_vs_WT_F08.06745.06745.2 0.0109 20-Oct R.EEKDNIQPTTE.- sp|Q9Y2W1|TR150_HUMAN 1 1302.5939 3.23 112294 6745 2 1302.5923 652.3042 Thyroid hormone receptor-associated protein 3 OS=Homo sapiens OX=9606 GN=THRAP3 PE=1 SV=2 4.24 1658.4 - 1.30E+06 - - - -1.259 - 1.747 0.317 - 318.8 1 2 1 -0.0016 11 0 0 0 9.37E+07 2.90E+07 - - - 2.8911 0.9917 221125_WJC_METTL3_EV_vs_WT_F08.06749.06749.2 0.00026 18-Nov R.NTEEEGLKYK.S "sp|Q9NYF8|BCLF1_HUMAN,tr|E9PKI6|E9PKI6_HUMAN,tr|A0A1W2PQ43|A0A1W2PQ43_HUMAN,tr|E9PK91|E9PK91_HUMAN,tr|E9PK09|E9PK09_HUMAN,tr|E9PQN2|E9PQN2_HUMAN" 6 1209.5877 2.44 112296 6749 2 1209.584345 605.8011 Bcl-2-associated transcription factor 1 OS=Homo sapiens OX=9606 GN=BCLAF1 PE=1 SV=2 4.79 1658.8 - 2.93E+06 - - - -2.801 - 2.18 0.395 - 503.1 1 2 1 -0.0034 10 0 0 0 8.55E+07 3.51E+07 - - - 4.1327 0.9691 221125_WJC_METTL3_EV_vs_WT_F08.06755.06755.3 0.0993 Sep-40 K.AQYEDIAQKSK.A sp|P04264|K2C1_HUMAN 1 1279.6408 48.06 112298 6755 3 1279.638739 427.5542 "Keratin, type II cytoskeletal 1 OS=Homo sapiens OX=9606 GN=KRT1 PE=1 SV=6" 6.11 1659.6 - 1.18E+06 - - - -1.6348 - 1.395 0.248 - 81 1 2 1 -0.0021 11 0 0 0 4.82E+07 1.00E+06 - - - 2.2501 0.997 221125_WJC_METTL3_EV_vs_WT_F08.06759.06759.2 0.000869 20-Oct R.EEK[136.11]DNIQPTTE.- sp|Q9Y2W1|TR150_HUMAN 1 1310.6081 3.23 112301 6759 2 1310.607888 656.3113 Thyroid hormone receptor-associated protein 3 OS=Homo sapiens OX=9606 GN=THRAP3 PE=1 SV=2 4.24 1660.1 - 985141 - - - -0.1923 - 1.743 0.429 - 349.9 1 2 1 -0.0003 11 0 0 0 9.37E+07 2.90E+07 - - - 3.7126 0.9999 221125_WJC_METTL3_EV_vs_WT_F08.06762.06762.2 3.02E-05 13/26 K.KGPGEVAGTVTGQK[136.11].R "sp|Q86U44|MTA70_HUMAN,tr|F5H6D8|F5H6D8_HUMAN,tr|H0YFV6|H0YFV6_HUMAN,tr|B4DTN4|B4DTN4_HUMAN" 4 1335.7238 - 112303 6762 2 1335.722216 668.8692 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 8.59 1660.4 - 1.13E+07 - - - -1.1702 - 3.224 0.514 - 263.1 2 2 0 -0.0016 14 0 0 0 - - - - - 5.6401 0.9997 221125_WJC_METTL3_EV_vs_WT_F08.06773.06773.2 0.000139 13/22 R.EVFTSSSSSSSR.Q sp|P08779|K1C16_HUMAN 1 1259.563 999 112311 6773 2 1259.561758 630.7888 "Keratin, type I cytoskeletal 16 OS=Homo sapiens OX=9606 GN=KRT16 PE=1 SV=4" 6.1 1661.8 - 1.22E+06 - - - -0.9654 - 2.263 0.361 - 605.3 1 2 0 -0.0012 12 0 0 0 3.83E+08 0.00E+00 - - - 3.8558 0.9965 221125_WJC_METTL3_EV_vs_WT_F08.06774.06774.2 0.00146 18-Aug R.NTEEEGLK[136.11]YK[136.11].S "sp|Q9NYF8|BCLF1_HUMAN,tr|E9PKI6|E9PKI6_HUMAN,tr|A0A1W2PQ43|A0A1W2PQ43_HUMAN,tr|E9PK91|E9PK91_HUMAN,tr|E9PK09|E9PK09_HUMAN,tr|E9PQN2|E9PQN2_HUMAN" 6 1225.6161 2.44 112312 6774 2 1225.614877 613.8153 Bcl-2-associated transcription factor 1 OS=Homo sapiens OX=9606 GN=BCLAF1 PE=1 SV=2 4.79 1661.9 - 1.47E+06 - - - -1.0248 - 1.778 0.419 - 261 1 2 1 -0.0013 10 0 0 0 8.55E+07 3.51E+07 - - - 3.7417 1 221125_WJC_METTL3_EV_vs_WT_F08.06778.06778.2 1.60E-05 17/26 K.K[136.11]GPGEVAGTVTGQK[136.11].R "sp|Q86U44|MTA70_HUMAN,tr|F5H6D8|F5H6D8_HUMAN,tr|H0YFV6|H0YFV6_HUMAN,tr|B4DTN4|B4DTN4_HUMAN" 4 1343.738 0 112315 6778 2 1343.736208 672.8763 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 8.59 1662.4 - 1.38E+08 - - - -1.318 - 3.41 0.537 - 684 1 2 0 -0.0018 14 0 0 0 1.75E+09 5.79E+11 - - - 6.0851 0.9971 221125_WJC_METTL3_EV_vs_WT_F08.06780.06780.3 0.00373 Oct-36 R.NTEEEGLK[136.11]YK[136.11].S "sp|Q9NYF8|BCLF1_HUMAN,tr|E9PKI6|E9PKI6_HUMAN,tr|A0A1W2PQ43|A0A1W2PQ43_HUMAN,tr|E9PK91|E9PK91_HUMAN,tr|E9PK09|E9PK09_HUMAN,tr|E9PQN2|E9PQN2_HUMAN" 6 1225.6161 2.08 112316 6780 3 1225.613925 409.546 Bcl-2-associated transcription factor 1 OS=Homo sapiens OX=9606 GN=BCLAF1 PE=1 SV=2 4.79 1662.6 - 4.22E+06 - - - -1.8015 - 1.934 0.317 - 124.6 1 2 1 -0.0022 10 0 0 0 3.48E+08 1.68E+08 - - - 3.9999 1 221125_WJC_METTL3_EV_vs_WT_F08.06790.06790.2 1.79E-06 24-Dec K.QSNASSDVEVEEK[136.11].E sp|O75475|PSIP1_HUMAN 1 1428.646 0.25 112323 6790 2 1428.64159 715.3303 PC4 and SFRS1-interacting protein OS=Homo sapiens OX=9606 GN=PSIP1 PE=1 SV=1 4 1663.7 - 352078 - - - -3.0742 - 2.595 0.643 - 511.8 1 2 0 -0.0044 13 0 0 0 2.96E+06 1.16E+07 - - - 6.2362 0.9992 221125_WJC_METTL3_EV_vs_WT_F08.06794.06794.2 3.75E-05 22-Jul R.AFHNEAQVNPER.K "sp|P17987|TCPA_HUMAN,tr|F5H282|F5H282_HUMAN,tr|E7EQR6|E7EQR6_HUMAN" 3 1410.664 0.44 112325 6794 2 1410.661652 706.3393 T-complex protein 1 subunit alpha OS=Homo sapiens OX=9606 GN=TCP1 PE=1 SV=1 5.4 1664.1 - 329889 - - - -1.6829 - 1.81 0.342 - 81 1 2 0 -0.0024 12 0 0 0 1.31E+07 2.96E+07 - - - 3.1274 0.7696 221125_WJC_METTL3_EV_vs_WT_F08.06803.06803.3 0.666 Sep-36 K.ETDK[136.11]QILQNR[166.11].K "sp|Q9UM54|MYO6_HUMAN,tr|A0A590UK86|A0A590UK86_HUMAN,tr|A0A0D9SGC1|A0A0D9SGC1_HUMAN,tr|A0A0A0MRM8|A0A0A0MRM8_HUMAN,tr|A0A5F9ZI03|A0A5F9ZI03_HUMAN,tr|A0A590UK22|A0A590UK22_HUMAN,tr|A0A590UJY4|A0A590UJY4_HUMAN,tr|A0A590UJ40|A0A590UJ40_HUMAN,tr|A0A590UJ75|A0A590UJ75_HUMAN,tr|E7EW20|E7EW20_HUMAN,tr|A0A590UKB0|A0A590UKB0_HUMAN,tr|A0A1Y0BRN3|A0A1Y0BRN3_HUMAN" 12 1261.6745 1.02 112331 6803 3 1261.675721 421.5655 Unconventional myosin-VI OS=Homo sapiens OX=9606 GN=MYO6 PE=1 SV=4 6.17 1665.2 - 511212 - - - 0.9408 - 1.693 0.063 - 166.3 1 2 1 0.0012 10 0 0 0 1.43E+07 1.41E+07 - - - 0.7797 0.9987 221125_WJC_METTL3_EV_vs_WT_F08.06804.06804.3 0.0218 Aug-36 K.KVDFQDTNAR.S "sp|Q2YD98|UVSSA_HUMAN,tr|A0A7I2V3L2|A0A7I2V3L2_HUMAN,tr|A0A7I2V4K1|A0A7I2V4K1_HUMAN,tr|A0A7I2V554|A0A7I2V554_HUMAN" 4 1192.5837 6.23 112332 6804 3 1192.582373 398.5352 UV-stimulated scaffold protein A OS=Homo sapiens OX=9606 GN=UVSSA PE=1 SV=2 5.96 1665.3 - 496431 - - - -1.0708 - 1.415 0.323 - 115.7 1 2 0 -0.0013 10 0 0 0 7.74E+06 1.24E+06 - - - 3.1545 0.9893 221125_WJC_METTL3_EV_vs_WT_F08.06805.06805.3 0.187 Aug-36 R.HVFSAIHSTR[166.11].D sp|P46019|KPB2_HUMAN 1 1163.6075 0.55 112333 6805 3 1163.604838 388.8764 "Phosphorylase b kinase regulatory subunit alpha, liver isoform OS=Homo sapiens OX=9606 GN=PHKA2 PE=1 SV=1" 9.76 1665.5 - 457176 - - - -2.2972 - 1.579 0.214 - 75.6 1 2 0 -0.0027 10 0 0 0 1.47E+07 2.68E+07 - - - 2.2592 1 221125_WJC_METTL3_EV_vs_WT_F08.06819.06819.3 1.43E-07 14/52 K.K[136.11]GPGEVAGTVTGQK[136.11].R "sp|Q86U44|MTA70_HUMAN,tr|F5H6D8|F5H6D8_HUMAN,tr|H0YFV6|H0YFV6_HUMAN,tr|B4DTN4|B4DTN4_HUMAN" 4 1343.738 0 112341 6819 3 1343.73868 448.9199 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 8.59 1667.2 - 1.65E+08 - - - 0.5217 - 2.931 0.552 - 350.4 1 2 0 0.0007 14 0 0 0 1.08E+08 1.02E+12 - - - 7.5518 0.9526 221125_WJC_METTL3_EV_vs_WT_F08.06820.06820.3 1.17 Sep-48 K.ASSETAASRPFTR.F "sp|Q9BXA9|SALL3_HUMAN,tr|A0A087WXW6|A0A087WXW6_HUMAN,tr|A0A140TA74|A0A140TA74_HUMAN,tr|A0A140TA70|A0A140TA70_HUMAN,tr|A9JR48|A9JR48_HUMAN" 5 1379.6793 999 112342 6820 3 1379.677402 460.9004 Sal-like protein 3 OS=Homo sapiens OX=9606 GN=SALL3 PE=1 SV=2 9.64 1667.2 - 2.11E+06 - - - -1.4054 - 1.546 0.115 - 138.9 1 2 0 -0.0019 13 0 0 0 6.86E+07 0.00E+00 - - - 1.0028 0.9959 221125_WJC_METTL3_EV_vs_WT_F08.06821.06821.2 0.00972 28-Aug R.EGSQGELTPANSQSR[166.11].M "sp|Q13098|CSN1_HUMAN,tr|A0A096LP07|A0A096LP07_HUMAN,tr|A8K070|A8K070_HUMAN,tr|C9JFE4|C9JFE4_HUMAN,tr|J3QQX0|J3QQX0_HUMAN,tr|A0A096LPJ3|A0A096LPJ3_HUMAN" 6 1569.7258 0.85 112343 6821 2 1569.722387 785.8702 COP9 signalosome complex subunit 1 OS=Homo sapiens OX=9606 GN=GPS1 PE=1 SV=4 4.53 1667.4 - 279899 - - - -2.2048 - 1.492 0.26 - 124.2 1 2 0 -0.0035 15 0 0 0 6.33E+06 7.44E+06 - - - 1.944 0.998 221125_WJC_METTL3_EV_vs_WT_F08.06829.06829.2 0.173 28-Jun K.LAEAPSAQPNQTQEK[136.11].Q sp|Q15911|ZFHX3_HUMAN 1 1618.8042 1.15 112349 6829 2 1618.804129 810.4094 Zinc finger homeobox protein 3 OS=Homo sapiens OX=9606 GN=ZFHX3 PE=1 SV=2 4.53 1668.4 - 188440 - - - -0.0525 - 1.541 0.227 - 105 1 2 0 -0.0001 15 0 0 0 3.64E+06 3.17E+06 - - - 1.7807 0.9999 221125_WJC_METTL3_EV_vs_WT_F08.06844.06844.3 5.95E-05 Nov-40 R.GR[166.11]SDYDGIGSR[166.11].G "sp|O00571|DDX3X_HUMAN,tr|A0A2R8YFR4|A0A2R8YFR4_HUMAN,tr|A0A2R8YCW1|A0A2R8YCW1_HUMAN,tr|A0A2R8YDH3|A0A2R8YDH3_HUMAN,tr|A0A2R8Y645|A0A2R8Y645_HUMAN,tr|A0A2R8YF78|A0A2R8YF78_HUMAN,tr|A0A2R8YCU0|A0A2R8YCU0_HUMAN,tr|A0A0D9SFB3|A0A0D9SFB3_HUMAN,tr|A0A2R8YFS5|A0A2R8YFS5_HUMAN,tr|A0A0D9SF53|A0A0D9SF53_HUMAN,tr|A0A2R8Y650|A0A2R8Y650_HUMAN,tr|A0A2R8Y5G6|A0A2R8Y5G6_HUMAN,tr|A0A0D9SG12|A0A0D9SG12_HUMAN,tr|F6S8Q4|F6S8Q4_HUMAN,tr|A0A2U3TZJ9|A0A2U3TZJ9_HUMAN,tr|A0A2R8Y4A4|A0A2R8Y4A4_HUMAN,tr|A0A2R8YF89|A0A2R8YF89_HUMAN" 17 1201.5591 0.98 112360 6844 3 1201.559836 401.527 ATP-dependent RNA helicase DDX3X OS=Homo sapiens OX=9606 GN=DDX3X PE=1 SV=3 5.96 1670.3 - 738509 - - - 0.6508 - 2.209 0.546 - 145.4 1 2 1 0.0008 11 0 0 0 2.35E+07 2.41E+07 - - - 6.8786 0.9999 221125_WJC_METTL3_EV_vs_WT_F08.06845.06845.2 1.59E-05 20-Dec K.TEELKPQVEEK.N "sp|Q9UN86|G3BP2_HUMAN,tr|A0A7I2V3E2|A0A7I2V3E2_HUMAN,tr|A0A7I2V647|A0A7I2V647_HUMAN,tr|A0A7I2YQS2|A0A7I2YQS2_HUMAN,tr|A0A7I2YQD9|A0A7I2YQD9_HUMAN,tr|A0A7I2V3P9|A0A7I2V3P9_HUMAN" 6 1328.6824 999 112361 6845 2 1328.680162 665.3485 Ras GTPase-activating protein-binding protein 2 OS=Homo sapiens OX=9606 GN=G3BP2 PE=1 SV=2 4.49 1670.4 - 384486 - - - -1.655 - 2.556 0.546 - 557.3 1 2 0 -0.0022 11 0 0 0 1.04E+07 0.00E+00 - - - 5.6118 0.9995 221125_WJC_METTL3_EV_vs_WT_F08.06846.06846.3 0.00517 13/40 K.TEELKPQVEEK.N "sp|Q9UN86|G3BP2_HUMAN,tr|A0A7I2V3E2|A0A7I2V3E2_HUMAN,tr|A0A7I2V647|A0A7I2V647_HUMAN,tr|A0A7I2YQS2|A0A7I2YQS2_HUMAN,tr|A0A7I2YQD9|A0A7I2YQD9_HUMAN,tr|A0A7I2V3P9|A0A7I2V3P9_HUMAN" 6 1328.6824 148.2 112362 6846 3 1328.683609 443.9014 Ras GTPase-activating protein-binding protein 2 OS=Homo sapiens OX=9606 GN=G3BP2 PE=1 SV=2 4.49 1670.5 - 4.55E+06 - - - 0.9393 - 2.341 0.261 - 210.8 1 2 0 0.0012 11 0 0 0 1.27E+08 8.54E+05 - - - 3.8659 0.9844 221125_WJC_METTL3_EV_vs_WT_F08.06847.06847.2 2.84E-05 14/22 G.PGEVAGTVTGQK[136.11].R "sp|Q86U44|MTA70_HUMAN,tr|F5H6D8|F5H6D8_HUMAN,tr|H0YFV6|H0YFV6_HUMAN,tr|B4DTN4|B4DTN4_HUMAN" 4 1150.6074 5.81 112363 6847 2 1150.609487 576.311 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 6.43 1670.6 - 1.78E+06 - - - 1.8555 - 2.566 0.444 - 755.8 1 1 0 0.0021 12 0 0 0 2.87E+08 4.94E+07 - - - 4.7992 0.9979 221125_WJC_METTL3_EV_vs_WT_F08.06848.06848.3 0.0192 13/36 K.TKSPFEQHIK.N sp|Q92520|FAM3C_HUMAN 1 1213.6455 0.76 112364 6848 3 1213.646215 405.5558 Protein FAM3C OS=Homo sapiens OX=9606 GN=FAM3C PE=1 SV=1 8.29 1670.7 - 470710 - - - 0.571 - 2.311 0.262 - 224.5 1 2 1 0.0007 10 0 0 0 3.78E+06 4.99E+06 - - - 3.9072 0.9997 221125_WJC_METTL3_EV_vs_WT_F08.06849.06849.3 0.00969 Dec-48 K.VFVEDDENSSQK[136.11]R[166.11].S sp|Q9ULJ3|ZBT21_HUMAN 1 1569.739 0.66 112365 6849 3 1569.743042 524.2536 Zinc finger and BTB domain-containing protein 21 OS=Homo sapiens OX=9606 GN=ZBTB21 PE=1 SV=2 4.32 1670.8 - 402407 - - - 2.5845 - 2.222 0.414 - 113.4 1 2 0 0.0041 13 0 0 0 3.15E+06 4.75E+06 - - - 5.3193 0.9998 221125_WJC_METTL3_EV_vs_WT_F08.06850.06850.2 0.00159 16-Jun R.SQESGYYDR[166.11].M "sp|P43243|MATR3_HUMAN,tr|A8MXP9|A8MXP9_HUMAN,tr|D6R991|D6R991_HUMAN,tr|A0A0R4J2E8|A0A0R4J2E8_HUMAN,tr|D6REM6|D6REM6_HUMAN" 5 1113.4602 1.35 112366 6850 2 1113.460738 557.7374 Matrin-3 OS=Homo sapiens OX=9606 GN=MATR3 PE=1 SV=2 4.37 1670.9 - 384407 - - - 0.4499 - 1.564 0.541 - 182.3 1 2 0 0.0005 9 0 0 0 7.05E+06 5.21E+06 - - - 4.3306 0.9998 221125_WJC_METTL3_EV_vs_WT_F08.06851.06851.2 0.00195 16-Aug R.SQESGYYDR.M "sp|P43243|MATR3_HUMAN,tr|A8MXP9|A8MXP9_HUMAN,tr|D6R991|D6R991_HUMAN,tr|A0A0R4J2E8|A0A0R4J2E8_HUMAN,tr|D6REM6|D6REM6_HUMAN" 5 1103.452 1.35 112367 6851 2 1103.452667 552.7333 Matrin-3 OS=Homo sapiens OX=9606 GN=MATR3 PE=1 SV=2 4.37 1671.1 - 346007 - - - 0.6344 - 1.676 0.486 - 330.4 1 2 0 0.0007 9 0 0 0 7.05E+06 5.21E+06 - - - 4.1244 1 221125_WJC_METTL3_EV_vs_WT_F08.06854.06854.2 5.42E-08 30-Dec R.AGGDATDSSQTALDNK.A "sp|O75122|CLAP2_HUMAN,tr|E7ERI8|E7ERI8_HUMAN,tr|A0A804HJG7|A0A804HJG7_HUMAN,tr|H7C4X8|H7C4X8_HUMAN,tr|J3KR49|J3KR49_HUMAN,tr|E7EW49|E7EW49_HUMAN,tr|E3W994|E3W994_HUMAN,tr|A0A0U1RQI6|A0A0U1RQI6_HUMAN" 8 1549.6856 0.3 112370 6854 2 1549.687459 775.8501 CLIP-associating protein 2 OS=Homo sapiens OX=9606 GN=CLASP2 PE=1 SV=3 3.93 1671.5 - 241651 - - - 1.1938 - 2.742 0.659 - 466.7 1 2 0 0.0019 16 0 0 0 3.17E+06 1.06E+07 - - - 6.3877 0.9916 221125_WJC_METTL3_EV_vs_WT_F08.06856.06856.2 0.0654 24-Jun R.FSSSSGYGGGSSR.V sp|P35527|K1C9_HUMAN 1 1234.5214 999 112372 6856 2 1234.523044 618.268 "Keratin, type I cytoskeletal 9 OS=Homo sapiens OX=9606 GN=KRT9 PE=1 SV=3" 8.75 1671.7 - 99132.4 - - - 1.296 - 1.186 0.211 - 71.5 1 2 0 0.0016 13 0 0 0 5.49E+05 0.00E+00 - - - 1.0368 0.9994 221125_WJC_METTL3_EV_vs_WT_F08.06860.06860.3 0.00649 Nov-52 R.ASAAPK[136.11]PEPVPVQK[136.11].G "sp|Q96HC4|PDLI5_HUMAN,tr|H0YBI4|H0YBI4_HUMAN,tr|H0Y929|H0Y929_HUMAN,tr|A0A0D9SFR4|A0A0D9SFR4_HUMAN" 4 1433.8213 0.82 112374 6860 3 1433.822398 478.9477 PDZ and LIM domain protein 5 OS=Homo sapiens OX=9606 GN=PDLIM5 PE=1 SV=5 8.64 1672.2 - 1.44E+06 - - - 0.7553 - 1.844 0.321 - 138.7 1 2 0 0.0011 14 0 0 0 2.05E+07 2.48E+07 - - - 3.7448 0.9994 221125_WJC_METTL3_EV_vs_WT_F08.06861.06861.3 0.000163 Nov-40 R.GRSDYDGIGSR.G "sp|O00571|DDX3X_HUMAN,tr|A0A2R8YFR4|A0A2R8YFR4_HUMAN,tr|A0A2R8YCW1|A0A2R8YCW1_HUMAN,tr|A0A2R8YDH3|A0A2R8YDH3_HUMAN,tr|A0A2R8Y645|A0A2R8Y645_HUMAN,tr|A0A2R8YF78|A0A2R8YF78_HUMAN,tr|A0A2R8YCU0|A0A2R8YCU0_HUMAN,tr|A0A0D9SFB3|A0A0D9SFB3_HUMAN,tr|A0A2R8YFS5|A0A2R8YFS5_HUMAN,tr|A0A0D9SF53|A0A0D9SF53_HUMAN,tr|A0A2R8Y650|A0A2R8Y650_HUMAN,tr|A0A2R8Y5G6|A0A2R8Y5G6_HUMAN,tr|A0A0D9SG12|A0A0D9SG12_HUMAN,tr|F6S8Q4|F6S8Q4_HUMAN,tr|A0A2U3TZJ9|A0A2U3TZJ9_HUMAN,tr|A0A2R8Y4A4|A0A2R8Y4A4_HUMAN,tr|A0A2R8YF89|A0A2R8YF89_HUMAN" 17 1181.5425 0.99 112375 6861 3 1181.543917 394.8548 ATP-dependent RNA helicase DDX3X OS=Homo sapiens OX=9606 GN=DDX3X PE=1 SV=3 5.96 1672.3 - 1.20E+06 - - - 1.1874 - 1.936 0.422 - 156.7 1 2 1 0.0014 11 0 0 0 2.37E+07 2.40E+07 - - - 5.1212 0.9994 221125_WJC_METTL3_EV_vs_WT_F08.06862.06862.3 0.127 Dec-40 R.SAEQISDSVRR.H sp|O43819|SCO2_HUMAN 1 1246.6266 0.17 112376 6862 3 1246.628021 416.5495 "Protein SCO2 homolog, mitochondrial OS=Homo sapiens OX=9606 GN=SCO2 PE=1 SV=3" 5.79 1672.4 - 950263 - - - 1.1575 - 2.249 0.264 - 231.5 1 2 0 0.0014 11 0 0 0 2.49E+07 1.45E+08 - - - 3.7854 0.9028 221125_WJC_METTL3_EV_vs_WT_F08.06865.06865.3 0.00173 Nov-36 L.K[136.11]VSELK[136.11]EELK[136.11].K "sp|Q00839|HNRPU_HUMAN,tr|A0A1W2PPS1|A0A1W2PPS1_HUMAN,tr|A0A1X7SBS1|A0A1X7SBS1_HUMAN" 3 1225.7344 0.88 112379 6865 3 1225.735358 409.5854 Heterogeneous nuclear ribonucleoprotein U OS=Homo sapiens OX=9606 GN=HNRNPU PE=1 SV=6 6.23 1672.7 - 385850 - - - 0.7783 - 2.278 0.317 - 140.4 1 1 1 0.001 10 0 0 0 2.14E+07 2.43E+07 - - - 4.4784 1 221125_WJC_METTL3_EV_vs_WT_F08.06866.06866.2 3.12E-06 20-Nov R.GR[166.11]SDYDGIGSR[166.11].G "sp|O00571|DDX3X_HUMAN,tr|A0A2R8YFR4|A0A2R8YFR4_HUMAN,tr|A0A2R8YCW1|A0A2R8YCW1_HUMAN,tr|A0A2R8YDH3|A0A2R8YDH3_HUMAN,tr|A0A2R8Y645|A0A2R8Y645_HUMAN,tr|A0A2R8YF78|A0A2R8YF78_HUMAN,tr|A0A2R8YCU0|A0A2R8YCU0_HUMAN,tr|A0A0D9SFB3|A0A0D9SFB3_HUMAN,tr|A0A2R8YFS5|A0A2R8YFS5_HUMAN,tr|A0A0D9SF53|A0A0D9SF53_HUMAN,tr|A0A2R8Y650|A0A2R8Y650_HUMAN,tr|A0A2R8Y5G6|A0A2R8Y5G6_HUMAN,tr|A0A0D9SG12|A0A0D9SG12_HUMAN,tr|F6S8Q4|F6S8Q4_HUMAN,tr|A0A2U3TZJ9|A0A2U3TZJ9_HUMAN,tr|A0A2R8Y4A4|A0A2R8Y4A4_HUMAN,tr|A0A2R8YF89|A0A2R8YF89_HUMAN" 17 1201.5591 1.13 112380 6866 2 1201.560718 601.7868 ATP-dependent RNA helicase DDX3X OS=Homo sapiens OX=9606 GN=DDX3X PE=1 SV=3 5.96 1672.8 - 312476 - - - 1.3849 - 2.469 0.603 - 277.3 1 2 1 0.0017 11 0 0 0 5.04E+06 4.47E+06 - - - 5.9393 0.9999 221125_WJC_METTL3_EV_vs_WT_F08.06867.06867.2 7.30E-07 20-Nov R.EGQNYQQNC[160.03]IK.E "sp|O96000|NDUBA_HUMAN,tr|H3BPJ9|H3BPJ9_HUMAN,tr|H3BV16|H3BV16_HUMAN" 3 1380.6092 1.94 112381 6867 2 1380.609696 691.3119 NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 10 OS=Homo sapiens OX=9606 GN=NDUFB10 PE=1 SV=3 6.09 1672.9 - 277251 - - - 0.3498 - 2.134 0.565 - 618 1 2 0 0.0005 11 0 0 0 1.55E+07 7.99E+06 - - - 5.2645 0.9943 221125_WJC_METTL3_EV_vs_WT_F08.06869.06869.2 1.01 20-Jul R.SAEQISDSVR[166.11]R[166.11].H sp|O43819|SCO2_HUMAN 1 1266.6431 0.79 112383 6869 2 1266.643696 634.3288 "Protein SCO2 homolog, mitochondrial OS=Homo sapiens OX=9606 GN=SCO2 PE=1 SV=3" 5.79 1673.2 - 172120 - - - 0.4563 - 1.474 0.131 - 72.6 1 2 0 0.0006 11 0 0 0 2.18E+06 2.76E+06 - - - 1.058 0.9997 221125_WJC_METTL3_EV_vs_WT_F08.06870.06870.2 0.000109 20-Aug R.EGQNYQQNC[160.03]IK[136.11].E "sp|O96000|NDUBA_HUMAN,tr|H3BPJ9|H3BPJ9_HUMAN,tr|H3BV16|H3BV16_HUMAN" 3 1388.6234 1.91 112384 6870 2 1388.624625 695.319 NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 10 OS=Homo sapiens OX=9606 GN=NDUFB10 PE=1 SV=3 6.09 1673.3 - 169269 - - - 0.8728 - 1.762 0.432 - 261.1 1 2 0 0.0012 11 0 0 0 1.56E+07 8.15E+06 - - - 3.7638 0.9999 221125_WJC_METTL3_EV_vs_WT_F08.06874.06874.2 0.000511 13/14 K.HQNVQLPR[166.11].E "sp|P26599|PTBP1_HUMAN,tr|A0A0U1RRM4|A0A0U1RRM4_HUMAN,tr|A6NLN1|A6NLN1_HUMAN,tr|A0A0D9SF20|A0A0D9SF20_HUMAN,tr|A0A7I2V621|A0A7I2V621_HUMAN,tr|K7EK45|K7EK45_HUMAN,tr|A0A087WUW5|A0A087WUW5_HUMAN" 7 1000.5442 0.81 112386 6874 2 1000.545153 501.2794 Polypyrimidine tract-binding protein 1 OS=Homo sapiens OX=9606 GN=PTBP1 PE=1 SV=1 9.76 1673.9 - 1.74E+06 - - - 0.9705 - 2.498 0.452 - 556.6 1 2 0 0.001 8 0 0 0 1.88E+07 2.31E+07 - - - 5.1402 0.9126 221125_WJC_METTL3_EV_vs_WT_F08.06875.06875.3 0.0638 Jul-40 K.LKDDEVAQLKK.S "sp|P07195|LDHB_HUMAN,tr|A0A5F9ZHM4|A0A5F9ZHM4_HUMAN" 2 1285.7242 0.96 112387 6875 3 1285.726311 429.582 L-lactate dehydrogenase B chain OS=Homo sapiens OX=9606 GN=LDHB PE=1 SV=2 6.12 1673.9 - 932911 - - - 1.6683 - 1.532 0.19 - 44.9 3 2 1 0.0021 11 0 0 0 5.76E+07 6.01E+07 - - - 1.6487 1 221125_WJC_METTL3_EV_vs_WT_F08.06878.06878.2 1.07E-12 16/30 R.AGAPAEEGAEAADNQR.E sp|Q9H0W5|CCDC8_HUMAN 1 1555.6863 2.08 112390 6878 2 1555.687478 778.8504 Coiled-coil domain-containing protein 8 OS=Homo sapiens OX=9606 GN=CCDC8 PE=1 SV=2 4 1674.3 - 518072 - - - 0.772 - 3.025 0.598 - 787.2 1 2 0 0.0012 16 0 0 0 1.15E+07 5.55E+06 - - - 6.1788 1 221125_WJC_METTL3_EV_vs_WT_F08.06879.06879.2 2.54E-05 14/22 K.HQLNELGSESAK[136.11].L "sp|Q6KC79|NIPBL_HUMAN,tr|A0A590UJS4|A0A590UJS4_HUMAN" 2 1319.6561 1.26 112391 6879 2 1319.655313 660.8353 Nipped-B-like protein OS=Homo sapiens OX=9606 GN=NIPBL PE=1 SV=2 5.4 1674.4 - 354857 - - - -0.5911 - 3.011 0.564 - 478.5 1 2 0 -0.0008 12 0 0 0 7.91E+06 6.28E+06 - - - 6.1067 0.9969 221125_WJC_METTL3_EV_vs_WT_F08.06886.06886.2 0.000299 24-Jun K.IQDK[136.11]EGIPPDQQR[166.11].L "sp|P62979|RS27A_HUMAN,sp|P0CG48|UBC_HUMAN,sp|P0CG48|UBC_HUMAN,sp|P0CG48|UBC_HUMAN,sp|P0CG48|UBC_HUMAN,sp|P0CG48|UBC_HUMAN,sp|P0CG48|UBC_HUMAN,sp|P0CG48|UBC_HUMAN,sp|P0CG48|UBC_HUMAN,sp|P0CG48|UBC_HUMAN,sp|P0CG47|UBB_HUMAN,sp|P0CG47|UBB_HUMAN,sp|P0CG47|UBB_HUMAN,sp|P62987|RL40_HUMAN,tr|F5H388|F5H388_HUMAN,tr|F5H388|F5H388_HUMAN,tr|F5GYU3|F5GYU3_HUMAN,tr|F5GYU3|F5GYU3_HUMAN,tr|B4DV12|B4DV12_HUMAN,tr|B4DV12|B4DV12_HUMAN,tr|J3QSA3|J3QSA3_HUMAN,tr|Q5PY61|Q5PY61_HUMAN,tr|Q5PY61|Q5PY61_HUMAN,tr|Q5PY61|Q5PY61_HUMAN,tr|F5H2Z3|F5H2Z3_HUMAN,tr|F5H2Z3|F5H2Z3_HUMAN,tr|M0R2S1|M0R2S1_HUMAN,tr|J3QS39|J3QS39_HUMAN,tr|J3QTR3|J3QTR3_HUMAN,tr|Q96C32|Q96C32_HUMAN,tr|Q96C32|Q96C32_HUMAN,tr|Q96C32|Q96C32_HUMAN,tr|Q96C32|Q96C32_HUMAN,tr|M0R1V7|M0R1V7_HUMAN,tr|F5H747|F5H747_HUMAN,tr|F5H747|F5H747_HUMAN,tr|F5GXK7|F5GXK7_HUMAN,tr|F5GXK7|F5GXK7_HUMAN,tr|M0R1M6|M0R1M6_HUMAN,tr|F5H6Q2|F5H6Q2_HUMAN,tr|F5H6Q2|F5H6Q2_HUMAN,tr|F5GZ39|F5GZ39_HUMAN,tr|J3QKN0|J3QKN0_HUMAN,tr|J3QKN0|J3QKN0_HUMAN,tr|F5H265|F5H265_HUMAN,tr|F5H265|F5H265_HUMAN,tr|A0A2R8Y422|A0A2R8Y422_HUMAN" 47 1540.7964 0.79 112398 6886 2 1540.796314 771.4055 Ubiquitin-40S ribosomal protein S27a OS=Homo sapiens OX=9606 GN=RPS27A PE=1 SV=2 4.56 1675.3 - 107233 - - - -0.0818 - 1.663 0.446 - 65.5 1 2 1 -0.0001 13 0 0 0 1.53E+06 1.94E+06 - - - 3.6405 0.9997 221125_WJC_METTL3_EV_vs_WT_F08.06889.06889.3 0.000105 14/48 K.IQDKEGIPPDQQR.L "sp|P62979|RS27A_HUMAN,sp|P0CG48|UBC_HUMAN,sp|P0CG48|UBC_HUMAN,sp|P0CG48|UBC_HUMAN,sp|P0CG48|UBC_HUMAN,sp|P0CG48|UBC_HUMAN,sp|P0CG48|UBC_HUMAN,sp|P0CG48|UBC_HUMAN,sp|P0CG48|UBC_HUMAN,sp|P0CG48|UBC_HUMAN,sp|P0CG47|UBB_HUMAN,sp|P0CG47|UBB_HUMAN,sp|P0CG47|UBB_HUMAN,sp|P62987|RL40_HUMAN,tr|F5H388|F5H388_HUMAN,tr|F5H388|F5H388_HUMAN,tr|F5GYU3|F5GYU3_HUMAN,tr|F5GYU3|F5GYU3_HUMAN,tr|B4DV12|B4DV12_HUMAN,tr|B4DV12|B4DV12_HUMAN,tr|J3QSA3|J3QSA3_HUMAN,tr|Q5PY61|Q5PY61_HUMAN,tr|Q5PY61|Q5PY61_HUMAN,tr|Q5PY61|Q5PY61_HUMAN,tr|F5H2Z3|F5H2Z3_HUMAN,tr|F5H2Z3|F5H2Z3_HUMAN,tr|M0R2S1|M0R2S1_HUMAN,tr|J3QS39|J3QS39_HUMAN,tr|J3QTR3|J3QTR3_HUMAN,tr|Q96C32|Q96C32_HUMAN,tr|Q96C32|Q96C32_HUMAN,tr|Q96C32|Q96C32_HUMAN,tr|Q96C32|Q96C32_HUMAN,tr|M0R1V7|M0R1V7_HUMAN,tr|F5H747|F5H747_HUMAN,tr|F5H747|F5H747_HUMAN,tr|F5GXK7|F5GXK7_HUMAN,tr|F5GXK7|F5GXK7_HUMAN,tr|M0R1M6|M0R1M6_HUMAN,tr|F5H6Q2|F5H6Q2_HUMAN,tr|F5H6Q2|F5H6Q2_HUMAN,tr|F5GZ39|F5GZ39_HUMAN,tr|J3QKN0|J3QKN0_HUMAN,tr|J3QKN0|J3QKN0_HUMAN,tr|F5H265|F5H265_HUMAN,tr|F5H265|F5H265_HUMAN,tr|A0A2R8Y422|A0A2R8Y422_HUMAN" 47 1522.774 0.64 112400 6889 3 1522.776174 508.5986 Ubiquitin-40S ribosomal protein S27a OS=Homo sapiens OX=9606 GN=RPS27A PE=1 SV=2 4.56 1675.7 - 1.96E+06 - - - 1.4474 - 2.549 0.432 - 289.6 1 2 1 0.0022 13 0 0 0 1.72E+07 2.71E+07 - - - 5.8927 0.9997 221125_WJC_METTL3_EV_vs_WT_F08.06891.06891.3 6.21E-05 Dec-40 K.LK[136.11]DDEVAQLK[136.11]K[136.11].S "sp|P07195|LDHB_HUMAN,tr|A0A5F9ZHM4|A0A5F9ZHM4_HUMAN" 2 1309.7668 0.83 112401 6891 3 1309.769288 437.5962 L-lactate dehydrogenase B chain OS=Homo sapiens OX=9606 GN=LDHB PE=1 SV=2 6.12 1675.9 - 2.18E+06 - - - 1.9255 - 2.116 0.512 - 132 1 2 1 0.0025 11 0 0 0 2.60E+07 3.14E+07 - - - 6.3769 0.9999 221125_WJC_METTL3_EV_vs_WT_F08.06893.06893.3 1.55E-08 15/60 R.AGAPAEEGAEAADNQR.E sp|Q9H0W5|CCDC8_HUMAN 1 1555.6863 2.14 112403 6893 3 1555.688702 519.5694 Coiled-coil domain-containing protein 8 OS=Homo sapiens OX=9606 GN=CCDC8 PE=1 SV=2 4 1676.1 - 846431 - - - 1.5588 - 2.469 0.392 - 264.8 1 2 0 0.0024 16 0 0 0 1.11E+07 5.19E+06 - - - 5.2288 1 221125_WJC_METTL3_EV_vs_WT_F08.06894.06894.2 7.86E-10 16/22 K.HQLNELGSESAK.L "sp|Q6KC79|NIPBL_HUMAN,tr|A0A590UJS4|A0A590UJS4_HUMAN" 2 1311.6419 1.33 112404 6894 2 1311.644228 656.8282 Nipped-B-like protein OS=Homo sapiens OX=9606 GN=NIPBL PE=1 SV=2 5.4 1676.2 - 563012 - - - 1.7802 - 3.074 0.648 - 699.2 1 2 0 0.0023 12 0 0 0 8.43E+06 6.36E+06 - - - 6.7811 0.9976 221125_WJC_METTL3_EV_vs_WT_F08.06895.06895.4 0.000649 13/72 K.VMEEEGLKDEEKR.L sp|Q15208|STK38_HUMAN 1 1590.7559 4.13 112405 6895 4 1590.759514 398.6963 Serine\threonine-protein kinase 38 OS=Homo sapiens OX=9606 GN=STK38 PE=1 SV=1 4.42 1676.3 - 272766 - - - 2.2486 - 2.282 0.348 - 169.1 1 2 1 0.0036 13 0 0 0 1.00E+08 2.42E+07 - - - 2.5599 0.99 221125_WJC_METTL3_EV_vs_WT_F08.06896.06896.2 0.0414 20-Jun R.SAEQISDSVRR.H sp|O43819|SCO2_HUMAN 1 1246.6266 0.84 112406 6896 2 1246.63145 624.3206 "Protein SCO2 homolog, mitochondrial OS=Homo sapiens OX=9606 GN=SCO2 PE=1 SV=3" 5.79 1676.5 - 235146 - - - 3.9081 - 1.438 0.304 - 60 1 2 0 0.0049 11 0 0 0 2.32E+06 2.76E+06 - - - 2.2675 1 221125_WJC_METTL3_EV_vs_WT_F08.06898.06898.2 2.61E-06 28-Nov R.VTVGDTSC[160.03]TGQGPSK.K "sp|Q15633|TRBP2_HUMAN,tr|F8VYK3|F8VYK3_HUMAN,tr|F8VZ57|F8VZ57_HUMAN,tr|F8VP94|F8VP94_HUMAN,tr|F8VTT7|F8VTT7_HUMAN,tr|F8VZZ7|F8VZZ7_HUMAN,tr|F8VYK6|F8VYK6_HUMAN" 7 1492.6828 2.31 112408 6898 2 1492.686364 747.3487 RISC-loading complex subunit TARBP2 OS=Homo sapiens OX=9606 GN=TARBP2 PE=1 SV=3 5.8 1676.7 - 136317 - - - 2.4064 - 2.436 0.65 - 406.4 1 2 0 0.0036 15 0 0 0 3.30E+06 1.43E+06 - - - 6.0298 0.9968 221125_WJC_METTL3_EV_vs_WT_F08.06903.06903.3 6.17E-05 Dec-52 K.AGNASK[136.11]DEIDSAVK[136.11].M "sp|P23381|SYWC_HUMAN,tr|G3V277|G3V277_HUMAN,tr|G3V3X0|G3V3X0_HUMAN,tr|G3V4S4|G3V4S4_HUMAN,tr|G3V4C7|G3V4C7_HUMAN,tr|G3V3P2|G3V3P2_HUMAN,tr|G3V5W1|G3V5W1_HUMAN,tr|G3V227|G3V227_HUMAN,tr|G3V313|G3V313_HUMAN,tr|G3V3S7|G3V3S7_HUMAN,tr|G3V2C0|G3V2C0_HUMAN,tr|G3V2F2|G3V2F2_HUMAN,tr|G3V4N8|G3V4N8_HUMAN,tr|G3V3R3|G3V3R3_HUMAN,tr|G3V339|G3V339_HUMAN" 15 1419.7176 1.24 112411 6903 3 1419.724185 474.2465 "Tryptophan--tRNA ligase, cytoplasmic OS=Homo sapiens OX=9606 GN=WARS1 PE=1 SV=2" 4.56 1677.4 - 934052 - - - 4.6115 - 2.181 0.465 - 192.9 1 2 1 0.0065 14 0 0 0 1.45E+07 1.17E+07 - - - 5.7948 0.9688 221125_WJC_METTL3_EV_vs_WT_F08.06905.06905.3 0.0251 Dec-40 R.LEKPAKYDDIK.K "sp|P04406|G3P_HUMAN,tr|E7EUT5|E7EUT5_HUMAN" 2 1318.7133 1.08 112413 6905 3 1318.715357 440.5784 Glyceraldehyde-3-phosphate dehydrogenase OS=Homo sapiens OX=9606 GN=GAPDH PE=1 SV=3 6.12 1677.5 - 1.81E+06 - - - 1.5849 - 1.651 0.208 - 156.9 1 2 1 0.0021 11 0 0 0 3.42E+08 3.16E+08 - - - 2.2828 0.9999 221125_WJC_METTL3_EV_vs_WT_F08.06906.06906.3 0.0191 16/48 K.VMEEEGLKDEEKR.L sp|Q15208|STK38_HUMAN 1 1590.7559 3.91 112414 6906 3 1590.75639 531.2593 Serine\threonine-protein kinase 38 OS=Homo sapiens OX=9606 GN=STK38 PE=1 SV=1 4.42 1677.6 - 464048 - - - 0.2848 - 3.362 0.461 - 430.3 1 2 1 0.0005 13 0 0 0 8.92E+07 2.28E+07 - - - 6.9671 1 221125_WJC_METTL3_EV_vs_WT_F08.06907.06907.3 1.22E-08 16/52 K.IHSDC[160.03]AANQQVTYR.L sp|Q02413|DSG1_HUMAN 1 1661.758 317.5 112415 6907 3 1661.761029 554.9266 Desmoglein-1 OS=Homo sapiens OX=9606 GN=DSG1 PE=1 SV=2 6.73 1677.8 - 390289 - - - 1.821 - 3.275 0.656 - 587.4 1 2 0 0.003 14 0 0 0 1.53E+08 4.83E+05 - - - 9.0056 0.995 221125_WJC_METTL3_EV_vs_WT_F08.06908.06908.2 5.52E-08 15/30 R.AGAPAEEGAEAADNQR[166.11].E sp|Q9H0W5|CCDC8_HUMAN 1 1565.6945 1.89 112416 6908 2 1566.699602 783.8545 Coiled-coil domain-containing protein 8 OS=Homo sapiens OX=9606 GN=CCDC8 PE=1 SV=2 4 1677.9 - 299837 - - - 641.9228 - 2.878 0.566 - 750.3 1 2 0 1.0051 16 0 0 0 1.05E+07 5.55E+06 - - - 5.5048 0.9998 221125_WJC_METTL3_EV_vs_WT_F08.06910.06910.2 5.39E-08 24-Sep R.C[160.03]DVTDNQSEVADK.T "sp|Q8N1F7|NUP93_HUMAN,tr|H3BPA9|H3BPA9_HUMAN,tr|H3BVG0|H3BVG0_HUMAN" 3 1479.6148 6.97 112418 6910 2 1479.617932 740.8147 Nuclear pore complex protein Nup93 OS=Homo sapiens OX=9606 GN=NUP93 PE=1 SV=2 3.84 1678.2 - 168636 - - - 2.1492 - 1.882 0.67 - 235.1 1 2 0 0.0032 13 0 0 0 1.55E+06 2.22E+05 - - - 5.6115 0.9999 221125_WJC_METTL3_EV_vs_WT_F08.06911.06911.2 2.98E-07 18-Oct K.NHEAQIQDMR[166.11].Q sp|P35580|MYH10_HUMAN 1 1250.5701 4.28 112419 6911 2 1250.570822 626.2923 Myosin-10 OS=Homo sapiens OX=9606 GN=MYH10 PE=1 SV=3 5.32 1678.3 - 149574 - - - 0.5462 - 2.006 0.628 - 450.6 1 2 0 0.0007 10 0 0 0 1.76E+07 4.10E+06 - - - 5.6223 0.9967 221125_WJC_METTL3_EV_vs_WT_F08.06916.06916.3 0.00368 Aug-52 K.AGNASKDEIDSAVK.M "sp|P23381|SYWC_HUMAN,tr|G3V277|G3V277_HUMAN,tr|G3V3X0|G3V3X0_HUMAN,tr|G3V4S4|G3V4S4_HUMAN,tr|G3V4C7|G3V4C7_HUMAN,tr|G3V3P2|G3V3P2_HUMAN,tr|G3V5W1|G3V5W1_HUMAN,tr|G3V227|G3V227_HUMAN,tr|G3V313|G3V313_HUMAN,tr|G3V3S7|G3V3S7_HUMAN,tr|G3V2C0|G3V2C0_HUMAN,tr|G3V2F2|G3V2F2_HUMAN,tr|G3V4N8|G3V4N8_HUMAN,tr|G3V3R3|G3V3R3_HUMAN,tr|G3V339|G3V339_HUMAN" 15 1403.6892 0.98 112422 6916 3 1403.690021 468.9037 "Tryptophan--tRNA ligase, cytoplasmic OS=Homo sapiens OX=9606 GN=WARS1 PE=1 SV=2" 4.56 1679 - 1.37E+06 - - - 0.5578 - 1.897 0.296 - 79 1 2 1 0.0008 14 0 0 0 1.49E+07 1.53E+07 - - - 3.5414 0.9642 221125_WJC_METTL3_EV_vs_WT_F08.06918.06918.3 0.000546 Dec-36 L.KVSELKEELK.K "sp|Q00839|HNRPU_HUMAN,tr|A0A1W2PPS1|A0A1W2PPS1_HUMAN,tr|A0A1X7SBS1|A0A1X7SBS1_HUMAN" 3 1201.6918 0.9 112424 6918 3 1201.692575 401.5712 Heterogeneous nuclear ribonucleoprotein U OS=Homo sapiens OX=9606 GN=HNRNPU PE=1 SV=6 6.23 1679.1 - 1.14E+06 - - - 0.6416 - 2.334 0.398 - 173.5 1 1 1 0.0008 10 0 0 0 1.99E+07 2.21E+07 - - - 5.4524 1 221125_WJC_METTL3_EV_vs_WT_F08.06919.06919.3 1.20E-05 14/64 K.GGYGAAAGGATRPPPPR.S sp|Q9ULL5|PRR12_HUMAN 1 1551.7906 2.04 112425 6919 3 1551.791533 518.2708 Proline-rich protein 12 OS=Homo sapiens OX=9606 GN=PRR12 PE=1 SV=3 10.84 1679.3 - 784848 - - - 0.5864 - 1.997 0.536 - 160.6 1 2 0 0.0009 17 0 0 0 2.20E+07 1.08E+07 - - - 6.2629 1 221125_WJC_METTL3_EV_vs_WT_F08.06921.06921.3 1.14E-05 17/56 K.NSLQEQQEEEEEAR[166.11]K[136.11].N sp|P35580|MYH10_HUMAN 1 1863.8565 0.96 112427 6921 3 1863.856853 622.2928 Myosin-10 OS=Homo sapiens OX=9606 GN=MYH10 PE=1 SV=3 4.21 1679.5 - 730475 - - - 0.1712 - 3.078 0.456 - 386.9 1 2 0 0.0003 15 0 0 0 1.64E+07 1.71E+07 - - - 6.5575 0.9999 221125_WJC_METTL3_EV_vs_WT_F08.06922.06922.3 9.90E-05 17/56 K.NSLQEQQEEEEEARK.N sp|P35580|MYH10_HUMAN 1 1845.8341 0.96 112428 6922 3 1845.838815 616.2853 Myosin-10 OS=Homo sapiens OX=9606 GN=MYH10 PE=1 SV=3 4.21 1679.7 - 620943 - - - 2.5739 - 3.313 0.464 - 553 1 2 0 0.0048 15 0 0 0 1.64E+07 1.71E+07 - - - 6.8375 0.9999 221125_WJC_METTL3_EV_vs_WT_F08.06923.06923.3 1.97E-07 16/48 K.VMEEEGLK[136.11]DEEK[136.11]R[166.11].L sp|Q15208|STK38_HUMAN 1 1616.7926 3.97 112429 6923 3 1616.793628 539.9381 Serine\threonine-protein kinase 38 OS=Homo sapiens OX=9606 GN=STK38 PE=1 SV=1 4.42 1679.8 - 541840 - - - 0.6315 - 2.663 0.545 - 324.5 1 2 1 0.001 13 0 0 0 8.91E+07 2.24E+07 - - - 7.2715 0.9985 221125_WJC_METTL3_EV_vs_WT_F08.06925.06925.2 9.68E-06 26-Sep K.AGNASK[136.11]DEIDSAVK[136.11].M "sp|P23381|SYWC_HUMAN,tr|G3V277|G3V277_HUMAN,tr|G3V3X0|G3V3X0_HUMAN,tr|G3V4S4|G3V4S4_HUMAN,tr|G3V4C7|G3V4C7_HUMAN,tr|G3V3P2|G3V3P2_HUMAN,tr|G3V5W1|G3V5W1_HUMAN,tr|G3V227|G3V227_HUMAN,tr|G3V313|G3V313_HUMAN,tr|G3V3S7|G3V3S7_HUMAN,tr|G3V2C0|G3V2C0_HUMAN,tr|G3V2F2|G3V2F2_HUMAN,tr|G3V4N8|G3V4N8_HUMAN,tr|G3V3R3|G3V3R3_HUMAN,tr|G3V339|G3V339_HUMAN" 15 1419.7176 1.05 112431 6925 2 1419.718458 710.8661 "Tryptophan--tRNA ligase, cytoplasmic OS=Homo sapiens OX=9606 GN=WARS1 PE=1 SV=2" 4.56 1680.1 - 210291 - - - 0.5776 - 1.965 0.552 - 249.4 1 2 1 0.0008 14 0 0 0 2.22E+06 2.11E+06 - - - 4.8129 1 221125_WJC_METTL3_EV_vs_WT_F08.06926.06926.2 5.84E-08 28-Oct R.VTVGDTSC[160.03]TGQGPSK[136.11].K "sp|Q15633|TRBP2_HUMAN,tr|F8VYK3|F8VYK3_HUMAN,tr|F8VZ57|F8VZ57_HUMAN,tr|F8VP94|F8VP94_HUMAN,tr|F8VTT7|F8VTT7_HUMAN,tr|F8VZZ7|F8VZZ7_HUMAN,tr|F8VYK6|F8VYK6_HUMAN" 7 1500.697 2.73 112432 6926 2 1500.70016 751.3558 RISC-loading complex subunit TARBP2 OS=Homo sapiens OX=9606 GN=TARBP2 PE=1 SV=3 5.8 1680.2 - 175184 - - - 2.1243 - 2.322 0.685 - 180.1 1 2 0 0.0032 15 0 0 0 3.90E+06 1.43E+06 - - - 6.1706 0.9999 221125_WJC_METTL3_EV_vs_WT_F08.06930.06930.3 0.000204 Sep-36 K.NHEAQIQDMR[166.11].Q sp|P35580|MYH10_HUMAN 1 1250.5701 0.92 112434 6930 3 1250.571379 417.864 Myosin-10 OS=Homo sapiens OX=9606 GN=MYH10 PE=1 SV=3 5.32 1680.6 - 1.81E+06 - - - 0.9915 - 2.153 0.445 - 197.6 1 2 0 0.0012 10 0 0 0 1.66E+07 1.79E+07 - - - 5.7405 0.9999 221125_WJC_METTL3_EV_vs_WT_F08.06931.06931.3 0.000403 Sep-36 K.NHEAQIQDMR.Q sp|P35580|MYH10_HUMAN 1 1240.5619 0.91 112435 6931 3 1240.562851 414.5279 Myosin-10 OS=Homo sapiens OX=9606 GN=MYH10 PE=1 SV=3 5.32 1680.7 - 1.50E+06 - - - 0.7916 - 2.128 0.377 - 196.1 1 2 0 0.001 10 0 0 0 1.67E+07 1.85E+07 - - - 4.9484 0.9999 221125_WJC_METTL3_EV_vs_WT_F08.06933.06933.3 2.55E-05 Nov-36 K.HTNYTMEHIR.V "sp|O43707|ACTN4_HUMAN,sp|P35609|ACTN2_HUMAN,sp|P12814|ACTN1_HUMAN,tr|A0A804HK61|A0A804HK61_HUMAN,tr|H7C5W8|H7C5W8_HUMAN,tr|A0A804HJU8|A0A804HJU8_HUMAN,tr|A0A804HIN7|A0A804HIN7_HUMAN,tr|H0YJ11|H0YJ11_HUMAN,tr|A0A494C060|A0A494C060_HUMAN,tr|H9KV75|H9KV75_HUMAN,tr|A0A804HLF4|A0A804HLF4_HUMAN,tr|H0YJW3|H0YJW3_HUMAN,tr|A0A7I2V4Y4|A0A7I2V4Y4_HUMAN,tr|A0A804HII9|A0A804HII9_HUMAN,tr|A0A804HL31|A0A804HL31_HUMAN,tr|A0A494C1A0|A0A494C1A0_HUMAN,tr|F5GXS2|F5GXS2_HUMAN,tr|A0A804HI95|A0A804HI95_HUMAN,tr|A0A804HKE2|A0A804HKE2_HUMAN,tr|A0A804HLD0|A0A804HLD0_HUMAN,tr|H7C144|H7C144_HUMAN" 21 1300.5983 0.77 112437 6933 3 1300.600169 434.54 Alpha-actinin-4 OS=Homo sapiens OX=9606 GN=ACTN4 PE=1 SV=2 6.92 1680.9 - 233493 - - - 1.4724 - 2.134 0.396 - 175.5 1 2 0 0.0019 10 0 0 0 9.24E+06 1.20E+07 - - - 5.1682 0.9998 221125_WJC_METTL3_EV_vs_WT_F08.06936.06936.2 0.000738 26-Jul K.IHSDC[160.03]AANQQVTYR.L sp|Q02413|DSG1_HUMAN 1 1661.758 999 112440 6936 2 1661.758726 831.8863 Desmoglein-1 OS=Homo sapiens OX=9606 GN=DSG1 PE=1 SV=2 6.73 1681.3 - 118336 - - - 0.4351 - 1.683 0.503 - 103.8 1 2 0 0.0007 14 0 0 0 6.12E+06 0.00E+00 - - - 4.0623 0.9964 221125_WJC_METTL3_EV_vs_WT_F08.06939.06939.3 0.037 13/48 K.IQDK[136.11]EGIPPDQQR[166.11].L "sp|P62979|RS27A_HUMAN,sp|P0CG48|UBC_HUMAN,sp|P0CG48|UBC_HUMAN,sp|P0CG48|UBC_HUMAN,sp|P0CG48|UBC_HUMAN,sp|P0CG48|UBC_HUMAN,sp|P0CG48|UBC_HUMAN,sp|P0CG48|UBC_HUMAN,sp|P0CG48|UBC_HUMAN,sp|P0CG48|UBC_HUMAN,sp|P0CG47|UBB_HUMAN,sp|P0CG47|UBB_HUMAN,sp|P0CG47|UBB_HUMAN,sp|P62987|RL40_HUMAN,tr|F5H388|F5H388_HUMAN,tr|F5H388|F5H388_HUMAN,tr|F5GYU3|F5GYU3_HUMAN,tr|F5GYU3|F5GYU3_HUMAN,tr|B4DV12|B4DV12_HUMAN,tr|B4DV12|B4DV12_HUMAN,tr|J3QSA3|J3QSA3_HUMAN,tr|Q5PY61|Q5PY61_HUMAN,tr|Q5PY61|Q5PY61_HUMAN,tr|Q5PY61|Q5PY61_HUMAN,tr|F5H2Z3|F5H2Z3_HUMAN,tr|F5H2Z3|F5H2Z3_HUMAN,tr|M0R2S1|M0R2S1_HUMAN,tr|J3QS39|J3QS39_HUMAN,tr|J3QTR3|J3QTR3_HUMAN,tr|Q96C32|Q96C32_HUMAN,tr|Q96C32|Q96C32_HUMAN,tr|Q96C32|Q96C32_HUMAN,tr|Q96C32|Q96C32_HUMAN,tr|M0R1V7|M0R1V7_HUMAN,tr|F5H747|F5H747_HUMAN,tr|F5H747|F5H747_HUMAN,tr|F5GXK7|F5GXK7_HUMAN,tr|F5GXK7|F5GXK7_HUMAN,tr|M0R1M6|M0R1M6_HUMAN,tr|F5H6Q2|F5H6Q2_HUMAN,tr|F5H6Q2|F5H6Q2_HUMAN,tr|F5GZ39|F5GZ39_HUMAN,tr|J3QKN0|J3QKN0_HUMAN,tr|J3QKN0|J3QKN0_HUMAN,tr|F5H265|F5H265_HUMAN,tr|F5H265|F5H265_HUMAN,tr|A0A2R8Y422|A0A2R8Y422_HUMAN" 47 1540.7964 0.35 112442 6939 3 1540.798207 514.6061 Ubiquitin-40S ribosomal protein S27a OS=Homo sapiens OX=9606 GN=RPS27A PE=1 SV=2 4.56 1681.6 - 2.78E+06 - - - 1.1468 - 2.003 0.286 - 254.9 1 2 1 0.0018 13 0 0 0 8.10E+07 2.33E+08 - - - 3.6115 0.9996 221125_WJC_METTL3_EV_vs_WT_F08.06941.06941.4 4.73E-05 Dec-72 K.VMEEEGLK[136.11]DEEK[136.11]R[166.11].L sp|Q15208|STK38_HUMAN 1 1616.7926 4.21 112444 6941 4 1616.794101 405.2054 Serine\threonine-protein kinase 38 OS=Homo sapiens OX=9606 GN=STK38 PE=1 SV=1 4.42 1681.8 - 1.67E+06 - - - 0.9241 - 2.225 0.424 - 133 1 2 1 0.0015 13 0 0 0 1.00E+08 2.38E+07 - - - 3.2126 1 221125_WJC_METTL3_EV_vs_WT_F08.06945.06945.3 1.12E-05 Nov-40 R.RGPAEESSSWR.D sp|Q14152|EIF3A_HUMAN 1 1260.5847 1.13 112448 6945 3 1260.585799 421.2022 Eukaryotic translation initiation factor 3 subunit A OS=Homo sapiens OX=9606 GN=EIF3A PE=1 SV=1 6.14 1682.2 - 456367 - - - 0.8615 - 2.236 0.52 - 245.2 1 2 0 0.0011 11 0 0 0 1.06E+07 9.34E+06 - - - 6.6232 0.9444 221125_WJC_METTL3_EV_vs_WT_F08.06946.06946.3 0.178 Oct-48 R.TIGSGEPGVPTKK.T "sp|Q5T8P6|RBM26_HUMAN,tr|A0A087X0H9|A0A087X0H9_HUMAN" 2 1269.6929 0.26 112449 6946 3 1269.694409 424.2382 RNA-binding protein 26 OS=Homo sapiens OX=9606 GN=RBM26 PE=1 SV=3 8.26 1682.3 - 425146 - - - 1.2153 - 1.506 0.113 - 110.8 1 2 0 0.0015 13 0 0 0 1.56E+07 6.03E+07 - - - 0.9096 0.998 221125_WJC_METTL3_EV_vs_WT_F08.06948.06948.3 0.000174 Oct-64 K.GGYGAAAGGATR[166.11]PPPPR[166.11].S sp|Q9ULL5|PRR12_HUMAN 1 1571.8072 2.06 112451 6948 3 1571.814071 524.943 Proline-rich protein 12 OS=Homo sapiens OX=9606 GN=PRR12 PE=1 SV=3 10.84 1682.6 - 356053 - - - 4.3949 - 1.746 0.42 - 93.1 1 2 0 0.0069 17 0 0 0 1.98E+07 9.58E+06 - - - 4.6286 0.9999 221125_WJC_METTL3_EV_vs_WT_F08.06953.06953.3 0.0306 Nov-52 R.LQSIGTENTEENRR.F "sp|P04075|ALDOA_HUMAN,tr|H3BR04|H3BR04_HUMAN,tr|H3BMQ8|H3BMQ8_HUMAN,tr|H3BQN4|H3BQN4_HUMAN,tr|H3BUH7|H3BUH7_HUMAN,tr|J3KPS3|J3KPS3_HUMAN,tr|H3BPS8|H3BPS8_HUMAN" 7 1645.802 1.52 112454 6953 3 1645.801878 549.6079 Fructose-bisphosphate aldolase A OS=Homo sapiens OX=9606 GN=ALDOA PE=1 SV=2 4.79 1683.3 - 1.33E+06 - - - -0.0595 - 2.027 0.406 - 125.8 1 2 0 -0.0001 14 0 0 0 1.12E+08 7.39E+07 - - - 4.9442 0.9963 221125_WJC_METTL3_EV_vs_WT_F08.06954.06954.2 0.00895 13/20 R.LEKPAKYDDIK.K "sp|P04406|G3P_HUMAN,tr|E7EUT5|E7EUT5_HUMAN" 2 1318.7133 1.43 112455 6954 2 1318.713747 660.3639 Glyceraldehyde-3-phosphate dehydrogenase OS=Homo sapiens OX=9606 GN=GAPDH PE=1 SV=3 6.12 1683.4 - 263517 - - - 0.364 - 2.184 0.32 - 391.6 1 2 1 0.0005 11 0 0 0 1.89E+07 1.32E+07 - - - 3.5176 0.9796 221125_WJC_METTL3_EV_vs_WT_F08.06957.06957.3 0.00609 Dec-52 K.TVAQSQQLETNSQR[166.11].D sp|P40938|RFC3_HUMAN 1 1598.7888 0.92 112458 6957 3 1598.794756 533.9369 Replication factor C subunit 3 OS=Homo sapiens OX=9606 GN=RFC3 PE=1 SV=2 5.66 1683.7 - 262529 - - - 3.7366 - 1.607 0.245 - 189.2 1 2 0 0.006 14 0 0 0 1.71E+07 1.87E+07 - - - 2.5305 0.9979 221125_WJC_METTL3_EV_vs_WT_F08.06958.06958.3 0.00222 Nov-48 K.K[136.11]AEGEPQEESPLK[136.11].S "sp|Q9NYF8|BCLF1_HUMAN,tr|E9PKI6|E9PKI6_HUMAN,tr|A0A1W2PQ43|A0A1W2PQ43_HUMAN,tr|E9PK91|E9PK91_HUMAN,tr|E9PJA7|E9PJA7_HUMAN,tr|E9PK09|E9PK09_HUMAN,tr|E9PQN2|E9PQN2_HUMAN" 7 1456.738 2.26 112459 6958 3 1456.744471 486.5866 Bcl-2-associated transcription factor 1 OS=Homo sapiens OX=9606 GN=BCLAF1 PE=1 SV=2 4.49 1683.9 - 235840 - - - 4.4153 - 2.211 0.349 - 146.2 1 2 0 0.0064 13 0 0 0 2.54E+09 1.13E+09 - - - 4.5805 0.9999 221125_WJC_METTL3_EV_vs_WT_F08.06959.06959.2 0.000132 14/26 K.TVAQSQQLETNSQR[166.11].D sp|P40938|RFC3_HUMAN 1 1598.7888 1.01 112460 6959 2 1598.79012 800.4017 Replication factor C subunit 3 OS=Homo sapiens OX=9606 GN=RFC3 PE=1 SV=2 5.66 1684 - 213624 - - - 0.8369 - 2.52 0.498 - 697.3 1 2 0 0.0013 14 0 0 0 2.25E+07 2.23E+07 - - - 5.0382 0.9997 221125_WJC_METTL3_EV_vs_WT_F08.06964.06964.3 7.85E-05 Dec-48 K.KAEGEPQEESPLK.S "sp|Q9NYF8|BCLF1_HUMAN,tr|E9PKI6|E9PKI6_HUMAN,tr|A0A1W2PQ43|A0A1W2PQ43_HUMAN,tr|E9PK91|E9PK91_HUMAN,tr|E9PJA7|E9PJA7_HUMAN,tr|E9PK09|E9PK09_HUMAN,tr|E9PQN2|E9PQN2_HUMAN" 7 1440.7096 2.28 112463 6964 3 1440.714154 481.2438 Bcl-2-associated transcription factor 1 OS=Homo sapiens OX=9606 GN=BCLAF1 PE=1 SV=2 4.49 1684.7 - 608973 - - - 3.1339 - 2.52 0.391 - 246.5 1 2 0 0.0045 13 0 0 0 2.68E+09 1.18E+09 - - - 5.4039 0.9996 221125_WJC_METTL3_EV_vs_WT_F08.06965.06965.2 0.00214 22-Aug R.ENQEGAANVNVR.G sp|Q8N0X7|SPART_HUMAN 1 1299.6167 1.27 112464 6965 2 1299.615765 650.8156 Spartin OS=Homo sapiens OX=9606 GN=SPART PE=1 SV=1 4.53 1684.8 - 308955 - - - -0.751 - 1.592 0.428 - 117 1 2 0 -0.001 12 0 0 0 9.03E+06 7.13E+06 - - - 3.4254 0.9939 221125_WJC_METTL3_EV_vs_WT_F08.06968.06968.3 0.00907 13/48 R.YLAEVATGDDKKR.L sp|P31947|1433S_HUMAN 1 1464.7573 8.69 112467 6968 3 1464.759397 489.2597 14-3-3 protein sigma OS=Homo sapiens OX=9606 GN=SFN PE=1 SV=1 6.12 1685.1 - 498733 - - - 1.461 - 1.902 0.275 - 155.8 1 2 1 0.0021 13 0 0 0 9.06E+06 1.04E+06 - - - 3.3485 1 221125_WJC_METTL3_EV_vs_WT_F08.06970.06970.2 1.36E-09 22-Dec R.ENQEGAANVNVR[166.11].G sp|Q8N0X7|SPART_HUMAN 1 1309.625 1.27 112469 6970 2 1309.623957 655.8198 Spartin OS=Homo sapiens OX=9606 GN=SPART PE=1 SV=1 4.53 1685.3 - 243974 - - - -0.8048 - 2.259 0.651 - 590.2 1 2 0 -0.0011 12 0 0 0 9.03E+06 7.13E+06 - - - 5.9932 0.9999 221125_WJC_METTL3_EV_vs_WT_F08.06977.06977.3 0.000412 14/48 K.KEAPPMEKPEVVK.T "sp|P62841|RS15_HUMAN,tr|K7EJ78|K7EJ78_HUMAN,tr|K7EM56|K7EM56_HUMAN,tr|A0A0B4J2B4|A0A0B4J2B4_HUMAN,tr|S4R456|S4R456_HUMAN,tr|K7ELC2|K7ELC2_HUMAN,tr|K7EQJ5|K7EQJ5_HUMAN,tr|S4R417|S4R417_HUMAN" 8 1480.796 1.5 112474 6977 3 1480.795789 494.6059 40S ribosomal protein S15 OS=Homo sapiens OX=9606 GN=RPS15 PE=1 SV=2 6.23 1686.2 - 1.34E+06 - - - -0.1094 - 2.488 0.393 - 217.3 1 2 0 -0.0002 13 0 0 0 4.43E+07 2.95E+07 - - - 5.3928 1 221125_WJC_METTL3_EV_vs_WT_F08.06978.06978.2 1.58E-06 26-Nov K.TVAQSQQLETNSQR.D sp|P40938|RFC3_HUMAN 1 1588.7805 1.01 112475 6978 2 1588.781083 795.3975 Replication factor C subunit 3 OS=Homo sapiens OX=9606 GN=RFC3 PE=1 SV=2 5.66 1686.4 - 763864 - - - 0.3594 - 2.813 0.574 - 360.1 1 2 0 0.0006 14 0 0 0 2.25E+07 2.23E+07 - - - 5.8758 0.9959 221125_WJC_METTL3_EV_vs_WT_F08.06985.06985.2 6.38E-05 20-Oct R.QAPQPQSSLQR.G "sp|Q8WXI9|P66B_HUMAN,tr|A0A0U1RRM1|A0A0U1RRM1_HUMAN,tr|A0A1B0GW07|A0A1B0GW07_HUMAN" 3 1238.6367 1.76 112480 6985 2 1238.634953 620.3257 Transcriptional repressor p66-beta OS=Homo sapiens OX=9606 GN=GATAD2B PE=1 SV=1 9.75 1687.2 - 610008 - - - -1.4492 - 1.58 0.172 - 283.2 1 2 0 -0.0018 11 0 0 0 1.17E+07 6.62E+06 - - - 1.5483 0.9999 221125_WJC_METTL3_EV_vs_WT_F08.06986.06986.2 8.91E-06 24-Oct K.KAEGEPQEESPLK.S "sp|Q9NYF8|BCLF1_HUMAN,tr|E9PKI6|E9PKI6_HUMAN,tr|A0A1W2PQ43|A0A1W2PQ43_HUMAN,tr|E9PK91|E9PK91_HUMAN,tr|E9PJA7|E9PJA7_HUMAN,tr|E9PK09|E9PK09_HUMAN,tr|E9PQN2|E9PQN2_HUMAN" 7 1440.7096 2.66 112481 6986 2 1440.711827 721.3621 Bcl-2-associated transcription factor 1 OS=Homo sapiens OX=9606 GN=BCLAF1 PE=1 SV=2 4.49 1687.3 - 263336 - - - 1.5187 - 2.501 0.565 - 280.4 1 2 0 0.0022 13 0 0 0 5.34E+08 2.00E+08 - - - 5.5661 1 221125_WJC_METTL3_EV_vs_WT_F08.06987.06987.3 1.45E-08 15/48 K.K[136.11]EAPPMEK[136.11]PEVVK[136.11].T "sp|P62841|RS15_HUMAN,tr|K7EJ78|K7EJ78_HUMAN,tr|K7EM56|K7EM56_HUMAN,tr|A0A0B4J2B4|A0A0B4J2B4_HUMAN,tr|S4R456|S4R456_HUMAN,tr|K7ELC2|K7ELC2_HUMAN,tr|K7EQJ5|K7EQJ5_HUMAN,tr|S4R417|S4R417_HUMAN" 8 1504.8386 1.52 112482 6987 3 1504.838049 502.6201 40S ribosomal protein S15 OS=Homo sapiens OX=9606 GN=RPS15 PE=1 SV=2 6.23 1687.4 - 1.11E+06 - - - -0.3336 - 3.013 0.555 - 258.7 1 2 0 -0.0005 13 0 0 0 4.45E+07 2.92E+07 - - - 7.7179 0.9849 221125_WJC_METTL3_EV_vs_WT_F08.06991.06991.2 0.0916 20-Jul R.QAPQPQSSLQR[166.11].G "sp|Q8WXI9|P66B_HUMAN,tr|A0A0U1RRM1|A0A0U1RRM1_HUMAN,tr|A0A1B0GW07|A0A1B0GW07_HUMAN" 3 1248.645 1.78 112484 6991 2 1248.644908 625.3298 Transcriptional repressor p66-beta OS=Homo sapiens OX=9606 GN=GATAD2B PE=1 SV=1 9.75 1688 - 290181 - - - -0.0881 - 1.287 0.083 - 128.9 1 2 0 -0.0001 11 0 0 0 1.16E+07 6.52E+06 - - - 0.3366 0.9917 221125_WJC_METTL3_EV_vs_WT_F08.06995.06995.2 0.257 26-May R.LQSIGTENTEENRR.F "sp|P04075|ALDOA_HUMAN,tr|H3BR04|H3BR04_HUMAN,tr|H3BMQ8|H3BMQ8_HUMAN,tr|H3BQN4|H3BQN4_HUMAN,tr|H3BUH7|H3BUH7_HUMAN,tr|J3KPS3|J3KPS3_HUMAN,tr|H3BPS8|H3BPS8_HUMAN" 7 1645.802 1.98 112488 6995 2 1645.803904 823.9083 Fructose-bisphosphate aldolase A OS=Homo sapiens OX=9606 GN=ALDOA PE=1 SV=2 4.79 1688.5 - 201197 - - - 1.1715 - 1.108 0.23 - 24.4 1 2 0 0.0019 14 0 0 0 2.83E+06 1.43E+06 - - - 0.9965 0.9999 221125_WJC_METTL3_EV_vs_WT_F08.06998.06998.3 0.000355 Dec-52 R.LQSIGTENTEENR[166.11]R[166.11].F "sp|P04075|ALDOA_HUMAN,tr|H3BR04|H3BR04_HUMAN,tr|H3BMQ8|H3BMQ8_HUMAN,tr|H3BQN4|H3BQN4_HUMAN,tr|H3BUH7|H3BUH7_HUMAN,tr|J3KPS3|J3KPS3_HUMAN,tr|H3BPS8|H3BPS8_HUMAN" 7 1665.8185 1.52 112489 6998 3 1665.819448 556.2801 Fructose-bisphosphate aldolase A OS=Homo sapiens OX=9606 GN=ALDOA PE=1 SV=2 4.79 1688.9 - 4.31E+06 - - - 0.5595 - 2.022 0.457 - 166.2 1 2 0 0.0009 14 0 0 0 1.12E+08 7.39E+07 - - - 5.506 1 221125_WJC_METTL3_EV_vs_WT_F08.07010.07010.3 2.68E-08 14/52 K.TVAQSQQLETNSQR.D sp|P40938|RFC3_HUMAN 1 1588.7805 0.88 112499 7010 3 1588.781733 530.6008 Replication factor C subunit 3 OS=Homo sapiens OX=9606 GN=RFC3 PE=1 SV=2 5.66 1690.3 - 1.20E+06 - - - 0.7685 - 2.938 0.468 - 243 1 2 0 0.0012 14 0 0 0 1.72E+07 1.96E+07 - - - 6.6215 0.9938 221125_WJC_METTL3_EV_vs_WT_F08.07016.07016.2 0.423 24-Apr K.NVESTNSNAYTQR.S sp|Q86V48|LUZP1_HUMAN 1 1482.6699 0.31 112505 7016 2 1482.668288 742.3422 Leucine zipper protein 1 OS=Homo sapiens OX=9606 GN=LUZP1 PE=1 SV=2 6 1691 - 113133 - - - -1.0866 - 1.186 0.22 - 39.7 1 2 0 -0.0016 13 0 0 0 9.86E+05 3.19E+06 - - - 1.1032 0.9705 221125_WJC_METTL3_EV_vs_WT_F08.07018.07018.2 0.397 26-May K.KGPGEVAGTVTGQK[136.11].R "sp|Q86U44|MTA70_HUMAN,tr|F5H6D8|F5H6D8_HUMAN,tr|H0YFV6|H0YFV6_HUMAN,tr|B4DTN4|B4DTN4_HUMAN" 4 1335.7238 - 112506 7018 2 1335.727064 668.8692 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 8.59 1691.2 - 146386 - - - 2.4593 - 1.224 0.178 - 42 3 2 0 0.0033 14 0 0 0 - - - - - 0.6488 0.9996 221125_WJC_METTL3_EV_vs_WT_F08.07021.07021.3 5.16E-05 13/64 K.AEAGPEGVAPAPEGEKK.Q "sp|Q9Y4L1|HYOU1_HUMAN,tr|A0A494C039|A0A494C039_HUMAN,tr|A0A087X054|A0A087X054_HUMAN" 3 1635.8104 1.3 112508 7021 3 1635.81202 546.2774 Hypoxia up-regulated protein 1 OS=Homo sapiens OX=9606 GN=HYOU1 PE=1 SV=1 4.49 1691.6 - 326515 - - - 0.9812 - 2.511 0.291 - 122.2 1 2 0 0.0016 17 0 0 0 7.76E+06 5.98E+06 - - - 4.1098 1 221125_WJC_METTL3_EV_vs_WT_F08.07022.07022.2 1.45E-10 16/24 K.K[136.11]AEGEPQEESPLK[136.11].S "sp|Q9NYF8|BCLF1_HUMAN,tr|E9PKI6|E9PKI6_HUMAN,tr|A0A1W2PQ43|A0A1W2PQ43_HUMAN,tr|E9PK91|E9PK91_HUMAN,tr|E9PJA7|E9PJA7_HUMAN,tr|E9PK09|E9PK09_HUMAN,tr|E9PQN2|E9PQN2_HUMAN" 7 1456.738 2.68 112509 7022 2 1456.741348 729.3763 Bcl-2-associated transcription factor 1 OS=Homo sapiens OX=9606 GN=BCLAF1 PE=1 SV=2 4.49 1691.7 - 283627 - - - 2.2715 - 3.122 0.583 - 795 1 2 0 0.0033 13 0 0 0 5.95E+08 2.22E+08 - - - 6.2679 1 221125_WJC_METTL3_EV_vs_WT_F08.07036.07036.2 5.05E-05 20/26 K.K[136.11]GPGEVAGTVTGQK[136.11].R "sp|Q86U44|MTA70_HUMAN,tr|F5H6D8|F5H6D8_HUMAN,tr|H0YFV6|H0YFV6_HUMAN,tr|B4DTN4|B4DTN4_HUMAN" 4 1343.738 0 112520 7036 2 1343.738761 672.8763 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 8.59 1693.4 - 3.10E+06 - - - 0.582 - 3.767 0.608 - 1144.1 1 2 0 0.0008 14 0 0 0 3.82E+05 1.39E+08 - - - 6.8597 0.9981 221125_WJC_METTL3_EV_vs_WT_F08.07037.07037.3 0.0523 Aug-52 K.KGPGEVAGTVTGQK[136.11].R "sp|Q86U44|MTA70_HUMAN,tr|F5H6D8|F5H6D8_HUMAN,tr|H0YFV6|H0YFV6_HUMAN,tr|B4DTN4|B4DTN4_HUMAN" 4 1335.7238 - 112521 7037 3 1335.72604 446.2485 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 8.59 1693.5 - 648749 - - - 1.6927 - 1.773 0.279 - 69.5 1 2 0 0.0023 14 0 0 0 - - - - - 3.1718 0.9995 221125_WJC_METTL3_EV_vs_WT_F08.07038.07038.3 0.00219 Oct-64 K.AEAGPEGVAPAPEGEK[136.11]K[136.11].Q "sp|Q9Y4L1|HYOU1_HUMAN,tr|A0A494C039|A0A494C039_HUMAN,tr|A0A087X054|A0A087X054_HUMAN" 3 1651.8388 1.31 112522 7038 3 1651.842158 551.6202 Hypoxia up-regulated protein 1 OS=Homo sapiens OX=9606 GN=HYOU1 PE=1 SV=1 4.49 1693.6 - 285051 - - - 2.0238 - 1.959 0.363 - 114.1 1 2 0 0.0033 17 0 0 0 7.76E+06 5.93E+06 - - - 4.2849 0.9992 221125_WJC_METTL3_EV_vs_WT_F08.07041.07041.2 0.00203 26-Jun K.STSTSEPTTGC[160.03]SLK[136.11].- sp|Q8ND82|Z280C_HUMAN 1 1462.6701 0.76 112525 7041 2 1462.672358 732.3423 Zinc finger protein 280C OS=Homo sapiens OX=9606 GN=ZNF280C PE=1 SV=1 5.72 1694 - 111200 - - - 1.5513 - 1.484 0.413 - 80.8 1 2 0 0.0023 14 0 0 0 2.82E+06 3.73E+06 - - - 3.0813 1 221125_WJC_METTL3_EV_vs_WT_F08.07044.07044.3 2.19E-06 16/52 R.MRPGVAC[160.03]SVSQAQK.D "sp|P32969|RL9_HUMAN,tr|H0Y9V9|H0Y9V9_HUMAN,tr|A0A2R8Y5Y7|A0A2R8Y5Y7_HUMAN" 3 1517.7443 0.78 112526 7044 3 1517.746237 506.922 60S ribosomal protein L9 OS=Homo sapiens OX=9606 GN=RPL9 PE=1 SV=1 9.5 1694.4 - 1.54E+06 - - - 1.298 - 3.07 0.528 - 427.2 1 2 0 0.002 14 0 0 0 3.64E+07 4.69E+07 - - - 7.407 1 221125_WJC_METTL3_EV_vs_WT_F08.07045.07045.3 4.85E-07 14/52 M.PC[160.03]SEETPAISPSK[136.11]R[166.11].A tr|H0YNJ9|H0YNJ9_HUMAN 1 1575.7682 0.21 112527 7045 3 1575.766454 526.2633 Deoxyuridine 5'-triphosphate nucleotidohydrolase OS=Homo sapiens OX=9606 GN=DUT PE=1 SV=1 6.52 1694.6 - 212308 - - - -1.0934 - 2.351 0.584 - 152.2 1 2 0 -0.0017 14 0 0 0 8.95E+06 4.20E+07 - - - 7.3223 0.9997 221125_WJC_METTL3_EV_vs_WT_F08.07050.07050.2 0.00013 26-Jun R.TVSTSSQPEENVDR.A sp|P42684|ABL2_HUMAN 1 1547.7063 1.59 112532 7050 2 1547.704456 774.8604 Tyrosine-protein kinase ABL2 OS=Homo sapiens OX=9606 GN=ABL2 PE=1 SV=1 4.14 1695.2 - 95434.8 - - - -1.2199 - 1.392 0.523 - 93 1 2 0 -0.0019 14 0 0 0 2.50E+06 1.57E+06 - - - 3.7333 0.9998 221125_WJC_METTL3_EV_vs_WT_F08.07055.07055.3 1.18E-06 13/56 K.QK[136.11]APAPEAEDEEVAR[166.11].R sp|Q8NBN7|RDH13_HUMAN 1 1656.8074 0.88 112535 7055 3 1656.807894 553.2764 Retinol dehydrogenase 13 OS=Homo sapiens OX=9606 GN=RDH13 PE=1 SV=2 4.25 1695.9 - 238072 - - - 0.2988 - 2.507 0.466 - 285.1 1 2 1 0.0005 15 0 0 0 3.75E+06 4.28E+06 - - - 6.1335 0.9825 221125_WJC_METTL3_EV_vs_WT_F08.07056.07056.2 0.0104 18-Sep R.STSHK[136.11]PDEIY.G sp|Q86U44|MTA70_HUMAN 1 1183.5601 0.01 112536 7056 2 1183.560298 592.7873 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 5.3 1696 - 429137 - - - 0.1943 - 1.885 0.379 - 235.9 1 1 0 0.0002 10 0 0 0 9.19E+04 7.43E+06 - - - 3.6097 0.9998 221125_WJC_METTL3_EV_vs_WT_F08.07065.07065.3 0.0126 15/44 K.SKAEAESLYQSK.Y sp|P04264|K2C1_HUMAN 1 1339.662 5257.22 112543 7065 3 1339.664429 447.5613 "Keratin, type II cytoskeletal 1 OS=Homo sapiens OX=9606 GN=KRT1 PE=1 SV=6" 5.86 1697.1 - 1.35E+07 - - - 1.843 - 2.788 0.474 - 405.7 1 2 1 0.0025 12 0 0 0 3.37E+10 6.40E+06 - - - 6.666 0.9992 221125_WJC_METTL3_EV_vs_WT_F08.07066.07066.3 0.000962 Dec-32 R.R[166.11]R[166.11]EEEMMIR[166.11].Q "sp|P23246|SFPQ_HUMAN,tr|H0Y9K7|H0Y9K7_HUMAN" 2 1278.6315 0.12 112544 7066 3 1278.632136 427.2178 "Splicing factor, proline- and glutamine-rich OS=Homo sapiens OX=9606 GN=SFPQ PE=1 SV=2" 6.23 1697.2 - 471082 - - - 0.481 - 1.928 0.371 - 205.1 1 2 1 0.0006 9 0 0 0 4.67E+07 3.99E+08 - - - 4.6546 0.9998 221125_WJC_METTL3_EV_vs_WT_F08.07068.07068.3 3.76E-05 Dec-56 K.QKAPAPEAEDEEVAR.R sp|Q8NBN7|RDH13_HUMAN 1 1638.7849 1 112546 7068 3 1638.7857 547.2689 Retinol dehydrogenase 13 OS=Homo sapiens OX=9606 GN=RDH13 PE=1 SV=2 4.25 1697.4 - 314923 - - - 0.4705 - 2.604 0.462 - 244.2 1 2 1 0.0008 15 0 0 0 3.62E+06 3.62E+06 - - - 6.1879 1 221125_WJC_METTL3_EV_vs_WT_F08.07072.07072.2 1.24E-08 18/22 K.SKAEAESLYQSK.Y sp|P04264|K2C1_HUMAN 1 1339.662 999 112548 7072 2 1339.661953 670.8383 "Keratin, type II cytoskeletal 1 OS=Homo sapiens OX=9606 GN=KRT1 PE=1 SV=6" 5.86 1698 - 6.91E+06 - - - -0.0052 - 3.131 0.672 - 810 1 2 1 0 12 0 0 0 1.07E+10 0.00E+00 - - - 7.0075 1 221125_WJC_METTL3_EV_vs_WT_F08.07074.07074.3 1.07E-06 13/44 R.DHSGSLGSSQLR.G sp|Q96L46|CPNS2_HUMAN 1 1242.5953 730.09 112550 7074 3 1242.595 415.2057 Calpain small subunit 2 OS=Homo sapiens OX=9606 GN=CAPNS2 PE=1 SV=2 6.74 1698.3 - 447578 - - - -0.2229 - 2.037 0.513 - 192.4 1 2 0 -0.0003 12 0 0 0 1.55E+08 2.13E+05 - - - 6.2315 0.973 221125_WJC_METTL3_EV_vs_WT_F08.07076.07076.3 0.027 Sep-32 R.RREEEMMIR.Q "sp|P23246|SFPQ_HUMAN,tr|H0Y9K7|H0Y9K7_HUMAN" 2 1248.6067 0.22 112552 7076 3 1248.606263 417.2095 "Splicing factor, proline- and glutamine-rich OS=Homo sapiens OX=9606 GN=SFPQ PE=1 SV=2" 6.23 1698.5 - 303196 - - - -0.3588 - 1.743 0.171 - 115.7 1 2 1 -0.0004 9 0 0 0 4.61E+07 2.13E+08 - - - 2.1208 1 221125_WJC_METTL3_EV_vs_WT_F08.07082.07082.2 3.28E-09 13/26 K.TESFQNAQAGSNPK.K "sp|Q92667|AKAP1_HUMAN,tr|I3L0W0|I3L0W0_HUMAN,tr|I3NI36|I3NI36_HUMAN" 3 1477.6797 1.24 112556 7082 2 1477.681799 739.8471 "A-kinase anchor protein 1, mitochondrial OS=Homo sapiens OX=9606 GN=AKAP1 PE=1 SV=1" 5.66 1699.3 - 291640 - - - 1.3968 - 2.796 0.633 - 597.2 1 2 0 0.0021 14 0 0 0 4.70E+06 3.80E+06 - - - 6.2959 1 221125_WJC_METTL3_EV_vs_WT_F08.07088.07088.2 7.90E-05 13/26 K.VNTQSSSNSTLPER[166.11].L sp|Q8IXW5|RPAP2_HUMAN 1 1528.7357 1.53 112560 7088 2 1528.734028 765.3751 Putative RNA polymerase II subunit B1 CTD phosphatase RPAP2 OS=Homo sapiens OX=9606 GN=RPAP2 PE=1 SV=1 5.97 1700 - 213176 - - - -1.0832 - 3.068 0.568 - 533.6 1 2 0 -0.0017 14 0 0 0 1.22E+07 7.96E+06 - - - 6.0489 0.9999 221125_WJC_METTL3_EV_vs_WT_F08.07090.07090.3 0.00138 14/48 R.TGSAVAPVHPPNR.S "sp|Q8IZL8|PELP1_HUMAN,tr|I3L1P4|I3L1P4_HUMAN,tr|C9JFV4|C9JFV4_HUMAN,tr|I3L445|I3L445_HUMAN,tr|I3L4M7|I3L4M7_HUMAN" 5 1301.684 1.31 112562 7090 3 1301.684129 434.902 "Proline-, glutamic acid- and leucine-rich protein 1 OS=Homo sapiens OX=9606 GN=PELP1 PE=1 SV=2" 9.44 1700.3 - 506072 - - - 0.0738 - 2.265 0.371 - 263.5 1 2 0 0.0001 13 0 0 0 1.28E+07 9.73E+06 - - - 4.8929 1 221125_WJC_METTL3_EV_vs_WT_F08.07091.07091.2 4.95E-07 13/22 K.VGGTSDVEVNEK[136.11].K "sp|P10809|CH60_HUMAN,tr|A0A7I2V2X6|A0A7I2V2X6_HUMAN,tr|A0A7I2YQK6|A0A7I2YQK6_HUMAN,tr|A0A7I2V599|A0A7I2V599_HUMAN" 4 1240.6027 2.31 112563 7091 2 1240.602238 621.3086 "60 kDa heat shock protein, mitochondrial OS=Homo sapiens OX=9606 GN=HSPD1 PE=1 SV=2" 4.14 1700.4 - 458395 - - - -0.341 - 2.652 0.604 - 900.3 1 2 0 -0.0004 12 0 0 0 1.43E+08 6.17E+07 - - - 6.0682 1 221125_WJC_METTL3_EV_vs_WT_F08.07092.07092.2 5.18E-09 26-Dec K.TESFQNAQAGSNPK[136.11].K "sp|Q92667|AKAP1_HUMAN,tr|I3L0W0|I3L0W0_HUMAN,tr|I3NI36|I3NI36_HUMAN" 3 1485.6939 1.24 112564 7092 2 1485.6924 743.8542 "A-kinase anchor protein 1, mitochondrial OS=Homo sapiens OX=9606 GN=AKAP1 PE=1 SV=1" 5.66 1700.5 - 272772 - - - -1.0332 - 2.584 0.643 - 587.6 1 2 0 -0.0015 14 0 0 0 4.70E+06 3.80E+06 - - - 6.172 0.9982 221125_WJC_METTL3_EV_vs_WT_F08.07097.07097.3 0.0296 Nov-44 K.LNGHQLENHALK[136.11].V sp|Q9NZI8|IF2B1_HUMAN 1 1380.7353 2.09 112567 7097 3 1380.734038 461.2524 Insulin-like growth factor 2 mRNA-binding protein 1 OS=Homo sapiens OX=9606 GN=IGF2BP1 PE=1 SV=2 6.92 1701.1 - 4.69E+06 - - - -0.948 - 1.791 0.247 - 126.4 1 2 0 -0.0013 12 0 0 0 1.00E+09 4.79E+08 - - - 2.9088 0.9998 221125_WJC_METTL3_EV_vs_WT_F08.07099.07099.3 0.00019 Nov-40 R.DEYR[166.11]QDYDAGR[166.11].G "sp|P52298|NCBP2_HUMAN,tr|C9JQX9|C9JQX9_HUMAN,tr|B3KSB0|B3KSB0_HUMAN" 3 1406.5966 26.51 112569 7099 3 1406.593229 469.8728 Nuclear cap-binding protein subunit 2 OS=Homo sapiens OX=9606 GN=NCBP2 PE=1 SV=1 4.23 1701.3 - 1.44E+06 - - - -2.3688 - 2.183 0.569 - 199.7 1 2 1 -0.0033 11 0 0 0 7.06E+08 2.66E+07 - - - 7.1007 0.9724 221125_WJC_METTL3_EV_vs_WT_F08.07101.07101.3 0.00117 Dec-40 L.NGHQLENHALK.V sp|Q9NZI8|IF2B1_HUMAN 1 1259.6371 1.84 112571 7101 3 1259.635602 420.8863 Insulin-like growth factor 2 mRNA-binding protein 1 OS=Homo sapiens OX=9606 GN=IGF2BP1 PE=1 SV=2 6.92 1701.5 - 741564 - - - -1.1757 - 1.881 0.363 - 140.8 1 1 0 -0.0015 11 0 0 0 8.21E+07 4.46E+07 - - - 4.3815 0.9997 221125_WJC_METTL3_EV_vs_WT_F08.07105.07105.2 0.00136 18-Oct K.AEAESLYQSK.Y sp|P04264|K2C1_HUMAN 1 1124.535 883.2 112572 7105 2 1124.536156 563.2748 "Keratin, type II cytoskeletal 1 OS=Homo sapiens OX=9606 GN=KRT1 PE=1 SV=6" 4.53 1702.1 - 470260 - - - 1.0555 - 2.025 0.421 - 400.3 1 2 0 0.0012 10 0 0 0 4.03E+07 4.56E+04 - - - 4.1196 0.9999 221125_WJC_METTL3_EV_vs_WT_F08.07116.07116.3 3.71E-05 14/44 K.LNGHQLENHALK.V sp|Q9NZI8|IF2B1_HUMAN 1 1372.7211 2.17 112580 7116 3 1372.718172 458.581 Insulin-like growth factor 2 mRNA-binding protein 1 OS=Homo sapiens OX=9606 GN=IGF2BP1 PE=1 SV=2 6.92 1703.3 - 1.78E+07 - - - -2.1672 - 2.801 0.469 - 261.1 1 2 0 -0.003 12 0 0 0 1.04E+09 4.79E+08 - - - 6.623 0.9999 221125_WJC_METTL3_EV_vs_WT_F08.07120.07120.2 1.46E-06 14/24 K.VEQATKPSFESGR.R "sp|P38159|RBMX_HUMAN,tr|H3BT71|H3BT71_HUMAN,tr|H0Y6E7|H0Y6E7_HUMAN" 3 1434.7103 1.65 112582 7120 2 1434.711639 718.3624 "RNA-binding motif protein, X chromosome OS=Homo sapiens OX=9606 GN=RBMX PE=1 SV=3" 6.11 1703.8 - 2.40E+06 - - - 0.9284 - 2.672 0.56 - 579.1 1 2 0 0.0013 13 0 0 0 3.24E+08 1.96E+08 - - - 5.6992 0.9998 221125_WJC_METTL3_EV_vs_WT_F08.07122.07122.2 0.000102 15/22 K.LNGHQLENHALK.V sp|Q9NZI8|IF2B1_HUMAN 1 1372.7211 2.5 112583 7122 2 1372.72373 687.3678 Insulin-like growth factor 2 mRNA-binding protein 1 OS=Homo sapiens OX=9606 GN=IGF2BP1 PE=1 SV=2 6.92 1704 - 1.54E+06 - - - 1.8817 - 2.823 0.503 - 834.6 1 2 0 0.0026 12 0 0 0 7.94E+07 3.18E+07 - - - 5.486 1 221125_WJC_METTL3_EV_vs_WT_F08.07123.07123.2 2.23E-12 18/22 K.LNGHQLENHALK[136.11].V sp|Q9NZI8|IF2B1_HUMAN 1 1380.7353 2.5 112584 7123 2 1380.731229 691.3749 Insulin-like growth factor 2 mRNA-binding protein 1 OS=Homo sapiens OX=9606 GN=IGF2BP1 PE=1 SV=2 6.92 1704.1 - 1.26E+06 - - - -2.9825 - 3.303 0.677 - 1308.3 1 2 0 -0.0041 12 0 0 0 7.94E+07 3.17E+07 - - - 7.1838 1 221125_WJC_METTL3_EV_vs_WT_F08.07124.07124.3 1.04E-07 16/48 K.VEQATK[136.11]PSFESGR[166.11].R "sp|P38159|RBMX_HUMAN,tr|H3BT71|H3BT71_HUMAN,tr|H0Y6E7|H0Y6E7_HUMAN" 3 1452.7328 1.46 112585 7124 3 1452.729577 485.2515 "RNA-binding motif protein, X chromosome OS=Homo sapiens OX=9606 GN=RBMX PE=1 SV=3" 6.11 1704.2 - 2.88E+07 - - - -2.2027 - 3.205 0.572 - 308.7 1 2 0 -0.0032 13 0 0 0 4.33E+09 2.97E+09 - - - 8.0742 0.9992 221125_WJC_METTL3_EV_vs_WT_F08.07127.07127.3 6.20E-06 16/36 R.TK[136.11]EHC[160.03]LMGIK[136.11].G sp|Q9HCE5|MET14_HUMAN 1 1231.6388 0.09 112588 7127 3 1231.636099 411.5535 N6-adenosine-methyltransferase non-catalytic subunit OS=Homo sapiens OX=9606 GN=METTL14 PE=1 SV=2 7.9 1704.5 - 1.09E+06 - - - -2.1922 - 2.714 0.351 - 263.8 1 2 1 -0.0027 10 0 0 0 1.21E+07 1.38E+08 - - - 5.3684 0.991 221125_WJC_METTL3_EV_vs_WT_F08.07128.07128.3 0.0459 Oct-40 K.LK[136.11]GDDLQAIK[136.11]K[136.11].E "sp|P07910|HNRPC_HUMAN,tr|B4DY08|B4DY08_HUMAN,tr|G3V5V7|G3V5V7_HUMAN,tr|B2R5W2|B2R5W2_HUMAN,tr|G3V4C1|G3V4C1_HUMAN,tr|G3V576|G3V576_HUMAN,tr|G3V2D6|G3V2D6_HUMAN,tr|G3V4W0|G3V4W0_HUMAN,tr|G3V2Q1|G3V2Q1_HUMAN" 9 1251.7613 1.37 112589 7128 3 1251.757554 418.261 Heterogeneous nuclear ribonucleoproteins C1\C2 OS=Homo sapiens OX=9606 GN=HNRNPC PE=1 SV=4 8.5 1704.6 - 1.05E+06 - - - -2.9822 - 1.638 0.344 - 70.3 1 2 1 -0.0037 11 0 0 0 6.58E+09 4.80E+09 - - - 3.7761 1 221125_WJC_METTL3_EV_vs_WT_F08.07130.07130.2 1.02E-05 16/20 S.KAEAESLYQSK.Y sp|P04264|K2C1_HUMAN 1 1252.6299 5.71 112590 7130 2 1252.628261 627.3222 "Keratin, type II cytoskeletal 1 OS=Homo sapiens OX=9606 GN=KRT1 PE=1 SV=6" 6.14 1704.9 - 760732 - - - -1.334 - 3.263 0.587 - 908.6 1 1 0 -0.0017 11 0 0 0 1.17E+07 2.05E+06 - - - 6.5754 0.9999 221125_WJC_METTL3_EV_vs_WT_F08.07133.07133.3 0.0299 13/48 K.VEQATKPSFESGR.R "sp|P38159|RBMX_HUMAN,tr|H3BT71|H3BT71_HUMAN,tr|H0Y6E7|H0Y6E7_HUMAN" 3 1434.7103 1.46 112591 7133 3 1434.707255 479.244 "RNA-binding motif protein, X chromosome OS=Homo sapiens OX=9606 GN=RBMX PE=1 SV=3" 6.11 1705.3 - 6.17E+07 - - - -2.1273 - 2.849 0.433 - 177.8 1 2 0 -0.0031 13 0 0 0 4.33E+09 2.96E+09 - - - 6.2053 0.9761 221125_WJC_METTL3_EV_vs_WT_F08.07137.07137.2 0.000476 20-Nov E.QATK[136.11]PSFESGR[166.11].R "sp|P38159|RBMX_HUMAN,tr|H3BT71|H3BT71_HUMAN,tr|H0Y6E7|H0Y6E7_HUMAN" 3 1224.6218 1.74 112595 7137 2 1224.618737 613.3182 "RNA-binding motif protein, X chromosome OS=Homo sapiens OX=9606 GN=RBMX PE=1 SV=3" 8.75 1705.7 - 737057 - - - -2.4767 - 1.874 0.534 - 309.1 1 1 0 -0.003 11 0 0 0 7.10E+07 4.07E+07 - - - 4.6833 0.9977 221125_WJC_METTL3_EV_vs_WT_F08.07139.07139.3 0.0162 15/48 K.IQDKEGIPPDQQR.L "sp|P62979|RS27A_HUMAN,sp|P0CG48|UBC_HUMAN,sp|P0CG48|UBC_HUMAN,sp|P0CG48|UBC_HUMAN,sp|P0CG48|UBC_HUMAN,sp|P0CG48|UBC_HUMAN,sp|P0CG48|UBC_HUMAN,sp|P0CG48|UBC_HUMAN,sp|P0CG48|UBC_HUMAN,sp|P0CG48|UBC_HUMAN,sp|P0CG47|UBB_HUMAN,sp|P0CG47|UBB_HUMAN,sp|P0CG47|UBB_HUMAN,sp|P62987|RL40_HUMAN,tr|F5H388|F5H388_HUMAN,tr|F5H388|F5H388_HUMAN,tr|F5GYU3|F5GYU3_HUMAN,tr|F5GYU3|F5GYU3_HUMAN,tr|B4DV12|B4DV12_HUMAN,tr|B4DV12|B4DV12_HUMAN,tr|J3QSA3|J3QSA3_HUMAN,tr|Q5PY61|Q5PY61_HUMAN,tr|Q5PY61|Q5PY61_HUMAN,tr|Q5PY61|Q5PY61_HUMAN,tr|F5H2Z3|F5H2Z3_HUMAN,tr|F5H2Z3|F5H2Z3_HUMAN,tr|M0R2S1|M0R2S1_HUMAN,tr|J3QS39|J3QS39_HUMAN,tr|J3QTR3|J3QTR3_HUMAN,tr|Q96C32|Q96C32_HUMAN,tr|Q96C32|Q96C32_HUMAN,tr|Q96C32|Q96C32_HUMAN,tr|Q96C32|Q96C32_HUMAN,tr|M0R1V7|M0R1V7_HUMAN,tr|F5H747|F5H747_HUMAN,tr|F5H747|F5H747_HUMAN,tr|F5GXK7|F5GXK7_HUMAN,tr|F5GXK7|F5GXK7_HUMAN,tr|M0R1M6|M0R1M6_HUMAN,tr|F5H6Q2|F5H6Q2_HUMAN,tr|F5H6Q2|F5H6Q2_HUMAN,tr|F5GZ39|F5GZ39_HUMAN,tr|J3QKN0|J3QKN0_HUMAN,tr|J3QKN0|J3QKN0_HUMAN,tr|F5H265|F5H265_HUMAN,tr|F5H265|F5H265_HUMAN,tr|A0A2R8Y422|A0A2R8Y422_HUMAN" 47 1522.774 0.67 112596 7139 3 1522.776785 508.5986 Ubiquitin-40S ribosomal protein S27a OS=Homo sapiens OX=9606 GN=RPS27A PE=1 SV=2 4.56 1705.9 - 1.66E+06 - - - 1.8486 - 2.207 0.322 - 173 1 2 1 0.0028 13 0 0 0 5.75E+07 8.62E+07 - - - 4.2756 0.9809 221125_WJC_METTL3_EV_vs_WT_F08.07141.07141.3 2.55E-06 15/40 L.NGHQLENHALK[136.11].V sp|Q9NZI8|IF2B1_HUMAN 1 1267.6513 1.92 112597 7141 3 1267.655515 423.5577 Insulin-like growth factor 2 mRNA-binding protein 1 OS=Homo sapiens OX=9606 GN=IGF2BP1 PE=1 SV=2 6.92 1706.1 - 2.13E+06 - - - 3.3385 - 2.317 0.476 - 233.7 1 1 0 0.0042 11 0 0 0 8.63E+07 4.49E+07 - - - 6.2328 0.9985 221125_WJC_METTL3_EV_vs_WT_F08.07145.07145.2 0.000103 14/24 K.VEQATK[136.11]PSFESGR[166.11].R "sp|P38159|RBMX_HUMAN,tr|H3BT71|H3BT71_HUMAN,tr|H0Y6E7|H0Y6E7_HUMAN" 3 1452.7328 1.65 112599 7145 2 1452.731815 727.3737 "RNA-binding motif protein, X chromosome OS=Homo sapiens OX=9606 GN=RBMX PE=1 SV=3" 6.11 1706.6 - 5.54E+06 - - - -0.6622 - 2.128 0.149 - 373.5 1 2 0 -0.001 13 0 0 0 3.24E+08 1.96E+08 - - - 2.0794 0.9937 221125_WJC_METTL3_EV_vs_WT_F08.07146.07146.2 1.17E-06 13/20 E.QATKPSFESGR.R "sp|P38159|RBMX_HUMAN,tr|H3BT71|H3BT71_HUMAN,tr|H0Y6E7|H0Y6E7_HUMAN" 3 1206.5993 1.74 112600 7146 2 1206.599254 604.3069 "RNA-binding motif protein, X chromosome OS=Homo sapiens OX=9606 GN=RBMX PE=1 SV=3" 8.75 1706.7 - 1.68E+06 - - - -0.0381 - 2.033 0.559 - 430.3 1 1 0 0 11 0 0 0 7.10E+07 4.08E+07 - - - 5.0892 0.9536 221125_WJC_METTL3_EV_vs_WT_F08.07161.07161.2 0.000781 14/22 V.EQATK[136.11]PSFESGR[166.11].R "sp|P38159|RBMX_HUMAN,tr|H3BT71|H3BT71_HUMAN,tr|H0Y6E7|H0Y6E7_HUMAN" 3 1353.6644 1.9 112610 7161 2 1353.660896 677.8395 "RNA-binding motif protein, X chromosome OS=Homo sapiens OX=9606 GN=RBMX PE=1 SV=3" 6.24 1708.4 - 2.07E+06 - - - -2.5612 - 2.287 0.349 - 447.1 1 1 0 -0.0035 12 0 0 0 6.03E+07 3.18E+07 - - - 3.7942 0.9994 221125_WJC_METTL3_EV_vs_WT_F08.07166.07166.3 0.266 14/40 K.LKGDDLQAIKK.E "sp|P07910|HNRPC_HUMAN,tr|B4DY08|B4DY08_HUMAN,tr|G3V5V7|G3V5V7_HUMAN,tr|B2R5W2|B2R5W2_HUMAN,tr|G3V4C1|G3V4C1_HUMAN,tr|G3V576|G3V576_HUMAN,tr|G3V2D6|G3V2D6_HUMAN,tr|G3V4W0|G3V4W0_HUMAN,tr|G3V2Q1|G3V2Q1_HUMAN" 9 1227.7187 1.37 112613 7166 3 1227.716122 410.2468 Heterogeneous nuclear ribonucleoproteins C1\C2 OS=Homo sapiens OX=9606 GN=HNRNPC PE=1 SV=4 8.5 1709 - 8.53E+06 - - - -2.0892 - 2.626 0.378 - 155.6 1 2 1 -0.0026 11 0 0 0 6.59E+09 4.81E+09 - - - 5.4963 1 221125_WJC_METTL3_EV_vs_WT_F08.07167.07167.2 1.23E-07 20-Oct R.ESEDSTDFNDK.L "sp|Q9Y399|RT02_HUMAN,tr|Q5T8A0|Q5T8A0_HUMAN" 2 1285.4946 1.09 112614 7167 2 1285.494016 643.7546 "28S ribosomal protein S2, mitochondrial OS=Homo sapiens OX=9606 GN=MRPS2 PE=1 SV=1" 3.77 1709.1 - 936061 - - - -0.4699 - 2.312 0.66 - 411.6 1 2 0 -0.0006 11 0 0 0 2.06E+07 1.88E+07 - - - 6.1829 0.9976 221125_WJC_METTL3_EV_vs_WT_F08.07172.07172.2 5.97E-06 14/20 K.LK[136.11]GDDLQAIK[136.11]K[136.11].E "sp|P07910|HNRPC_HUMAN,tr|B4DY08|B4DY08_HUMAN,tr|G3V5V7|G3V5V7_HUMAN,tr|B2R5W2|B2R5W2_HUMAN,tr|G3V4C1|G3V4C1_HUMAN,tr|G3V576|G3V576_HUMAN,tr|G3V2D6|G3V2D6_HUMAN,tr|G3V4W0|G3V4W0_HUMAN,tr|G3V2Q1|G3V2Q1_HUMAN" 9 1251.7613 1.43 112617 7172 2 1251.758871 626.8879 Heterogeneous nuclear ribonucleoproteins C1\C2 OS=Homo sapiens OX=9606 GN=HNRNPC PE=1 SV=4 8.5 1709.7 - 1.44E+06 - - - -1.9301 - 2.573 0.484 - 329.1 1 2 1 -0.0024 11 0 0 0 4.03E+08 2.81E+08 - - - 5.1717 0.9444 221125_WJC_METTL3_EV_vs_WT_F08.07175.07175.2 0.00658 18-Sep Q.ATKPSFESGR.R "sp|P38159|RBMX_HUMAN,tr|H3BT71|H3BT71_HUMAN,tr|H0Y6E7|H0Y6E7_HUMAN" 3 1078.5407 1.93 112618 7175 2 1078.540633 540.2776 "RNA-binding motif protein, X chromosome OS=Homo sapiens OX=9606 GN=RBMX PE=1 SV=3" 8.79 1710.1 - 1.58E+06 - - - -0.0834 - 1.423 0.319 - 138.8 1 1 0 -0.0001 10 0 0 0 2.47E+07 1.28E+07 - - - 2.3818 0.9878 221125_WJC_METTL3_EV_vs_WT_F08.07178.07178.2 0.000249 18-Nov Q.ATK[136.11]PSFESGR[166.11].R "sp|P38159|RBMX_HUMAN,tr|H3BT71|H3BT71_HUMAN,tr|H0Y6E7|H0Y6E7_HUMAN" 3 1096.5632 1.93 112621 7178 2 1096.56336 549.2889 "RNA-binding motif protein, X chromosome OS=Homo sapiens OX=9606 GN=RBMX PE=1 SV=3" 8.79 1710.4 - 706771 - - - 0.1523 - 1.64 0.493 - 227.2 1 1 0 0.0002 10 0 0 0 2.47E+07 1.28E+07 - - - 4.0631 0.9998 221125_WJC_METTL3_EV_vs_WT_F08.07182.07182.3 0.000544 Nov-48 K.FQDDNVEGDKVSK.K sp|Q92621|NU205_HUMAN 1 1479.6842 1.16 112623 7182 3 1479.682132 494.2353 Nuclear pore complex protein Nup205 OS=Homo sapiens OX=9606 GN=NUP205 PE=1 SV=3 4.23 1711 - 1.55E+06 - - - -1.3652 - 2.084 0.523 - 93 1 2 1 -0.002 13 0 0 0 3.09E+07 2.66E+07 - - - 6.3612 1 221125_WJC_METTL3_EV_vs_WT_F08.07188.07188.2 6.11E-07 20-Oct R.ESEDSTDFNDK[136.11].L "sp|Q9Y399|RT02_HUMAN,tr|Q5T8A0|Q5T8A0_HUMAN" 2 1293.5088 1.09 112629 7188 2 1293.50608 647.7617 "28S ribosomal protein S2, mitochondrial OS=Homo sapiens OX=9606 GN=MRPS2 PE=1 SV=1" 3.77 1711.5 - 809798 - - - -2.1183 - 2.312 0.649 - 441 1 2 0 -0.0027 11 0 0 0 2.06E+07 1.88E+07 - - - 6.1009 0.9996 221125_WJC_METTL3_EV_vs_WT_F08.07192.07192.3 0.000121 16/48 K.IQDK[136.11]EGIPPDQQR[166.11].L "sp|P62979|RS27A_HUMAN,sp|P0CG48|UBC_HUMAN,sp|P0CG48|UBC_HUMAN,sp|P0CG48|UBC_HUMAN,sp|P0CG48|UBC_HUMAN,sp|P0CG48|UBC_HUMAN,sp|P0CG48|UBC_HUMAN,sp|P0CG48|UBC_HUMAN,sp|P0CG48|UBC_HUMAN,sp|P0CG48|UBC_HUMAN,sp|P0CG47|UBB_HUMAN,sp|P0CG47|UBB_HUMAN,sp|P0CG47|UBB_HUMAN,sp|P62987|RL40_HUMAN,tr|F5H388|F5H388_HUMAN,tr|F5H388|F5H388_HUMAN,tr|F5GYU3|F5GYU3_HUMAN,tr|F5GYU3|F5GYU3_HUMAN,tr|B4DV12|B4DV12_HUMAN,tr|B4DV12|B4DV12_HUMAN,tr|J3QSA3|J3QSA3_HUMAN,tr|Q5PY61|Q5PY61_HUMAN,tr|Q5PY61|Q5PY61_HUMAN,tr|Q5PY61|Q5PY61_HUMAN,tr|F5H2Z3|F5H2Z3_HUMAN,tr|F5H2Z3|F5H2Z3_HUMAN,tr|M0R2S1|M0R2S1_HUMAN,tr|J3QS39|J3QS39_HUMAN,tr|J3QTR3|J3QTR3_HUMAN,tr|Q96C32|Q96C32_HUMAN,tr|Q96C32|Q96C32_HUMAN,tr|Q96C32|Q96C32_HUMAN,tr|Q96C32|Q96C32_HUMAN,tr|M0R1V7|M0R1V7_HUMAN,tr|F5H747|F5H747_HUMAN,tr|F5H747|F5H747_HUMAN,tr|F5GXK7|F5GXK7_HUMAN,tr|F5GXK7|F5GXK7_HUMAN,tr|M0R1M6|M0R1M6_HUMAN,tr|F5H6Q2|F5H6Q2_HUMAN,tr|F5H6Q2|F5H6Q2_HUMAN,tr|F5GZ39|F5GZ39_HUMAN,tr|J3QKN0|J3QKN0_HUMAN,tr|J3QKN0|J3QKN0_HUMAN,tr|F5H265|F5H265_HUMAN,tr|F5H265|F5H265_HUMAN,tr|A0A2R8Y422|A0A2R8Y422_HUMAN" 47 1540.7964 0.6 112632 7192 3 1540.796183 514.6061 Ubiquitin-40S ribosomal protein S27a OS=Homo sapiens OX=9606 GN=RPS27A PE=1 SV=2 4.56 1712 - 2.60E+06 - - - -0.1668 - 2.527 0.395 - 386.9 1 2 1 -0.0003 13 0 0 0 2.30E+07 3.81E+07 - - - 5.4572 1 221125_WJC_METTL3_EV_vs_WT_F08.07194.07194.2 4.16E-05 17/20 K.LKGDDLQAIKK.E "sp|P07910|HNRPC_HUMAN,tr|B4DY08|B4DY08_HUMAN,tr|G3V5V7|G3V5V7_HUMAN,tr|B2R5W2|B2R5W2_HUMAN,tr|G3V4C1|G3V4C1_HUMAN,tr|G3V576|G3V576_HUMAN,tr|G3V2D6|G3V2D6_HUMAN,tr|G3V4W0|G3V4W0_HUMAN,tr|G3V2Q1|G3V2Q1_HUMAN" 9 1227.7187 1.43 112633 7194 2 1227.717282 614.8666 Heterogeneous nuclear ribonucleoproteins C1\C2 OS=Homo sapiens OX=9606 GN=HNRNPC PE=1 SV=4 8.5 1712.2 - 2.47E+06 - - - -1.1444 - 2.904 0.52 - 547.7 1 2 1 -0.0014 11 0 0 0 4.03E+08 2.81E+08 - - - 5.7653 0.9957 221125_WJC_METTL3_EV_vs_WT_F08.07199.07199.3 0.0228 Aug-40 K.LK[136.11]GDDLQAIKK[136.11].E "sp|P07910|HNRPC_HUMAN,tr|B4DY08|B4DY08_HUMAN,tr|G3V5V7|G3V5V7_HUMAN,tr|B2R5W2|B2R5W2_HUMAN,tr|G3V4C1|G3V4C1_HUMAN,tr|G3V576|G3V576_HUMAN,tr|G3V2D6|G3V2D6_HUMAN,tr|G3V4W0|G3V4W0_HUMAN,tr|G3V2Q1|G3V2Q1_HUMAN" 9 1243.7471 - 112636 7199 3 1243.746906 415.5896 Heterogeneous nuclear ribonucleoproteins C1\C2 OS=Homo sapiens OX=9606 GN=HNRNPC PE=1 SV=4 8.5 1712.9 - 2.09E+06 - - - -0.1455 - 1.445 0.338 - 53.9 1 2 1 -0.0002 11 0 0 0 - - - - - 3.354 0.9932 221125_WJC_METTL3_EV_vs_WT_F08.07200.07200.3 0.0967 Sep-44 R.EGPDLDRPGSDR.Q "sp|Q7Z4V5|HDGR2_HUMAN,tr|A0A087WZ99|A0A087WZ99_HUMAN" 2 1312.6008 0.75 112637 7200 3 1312.601445 438.5409 Hepatoma-derived growth factor-related protein 2 OS=Homo sapiens OX=9606 GN=HDGFL2 PE=1 SV=1 4.23 1713 - 1.20E+06 - - - 0.5242 - 1.516 0.211 - 118.1 1 2 0 0.0007 12 0 0 0 1.26E+07 1.68E+07 - - - 2.0455 0.9934 221125_WJC_METTL3_EV_vs_WT_F08.07201.07201.2 7.09E-06 15/18 L.KGDDLQAIKK.E "sp|P07910|HNRPC_HUMAN,tr|B4DY08|B4DY08_HUMAN,tr|G3V5V7|G3V5V7_HUMAN,tr|B2R5W2|B2R5W2_HUMAN,tr|G3V4C1|G3V4C1_HUMAN,tr|G3V576|G3V576_HUMAN,tr|G3V2D6|G3V2D6_HUMAN,tr|G3V4W0|G3V4W0_HUMAN,tr|G3V2Q1|G3V2Q1_HUMAN" 9 1114.6346 2.86 112638 7201 2 1114.635286 558.3246 Heterogeneous nuclear ribonucleoproteins C1\C2 OS=Homo sapiens OX=9606 GN=HNRNPC PE=1 SV=4 8.5 1713.1 - 852957 - - - 0.5948 - 2.892 0.44 - 635 1 1 0 0.0007 10 0 0 0 8.91E+07 3.12E+07 - - - 5.2549 1 221125_WJC_METTL3_EV_vs_WT_F08.07206.07206.3 2.88E-06 15/48 R.TGSAVAPVHPPNR[166.11].S "sp|Q8IZL8|PELP1_HUMAN,tr|I3L1P4|I3L1P4_HUMAN,tr|C9JFV4|C9JFV4_HUMAN,tr|I3L445|I3L445_HUMAN,tr|I3L4M7|I3L4M7_HUMAN" 5 1311.6923 1.17 112640 7206 3 1311.693651 438.238 "Proline-, glutamic acid- and leucine-rich protein 1 OS=Homo sapiens OX=9606 GN=PELP1 PE=1 SV=2" 9.44 1713.8 - 901673 - - - 1.0277 - 2.953 0.444 - 430.6 1 2 0 0.0013 13 0 0 0 2.94E+07 2.51E+07 - - - 6.4256 1 221125_WJC_METTL3_EV_vs_WT_F08.07208.07208.3 7.01E-07 19/56 K.ELHSTPNGLSSESSR.K "sp|Q8N5Z5|KCD17_HUMAN,tr|A0A087WX35|A0A087WX35_HUMAN,tr|H0Y731|H0Y731_HUMAN" 3 1599.7489 4.16 112642 7208 3 1599.7454 534.2569 BTB\POZ domain-containing protein KCTD17 OS=Homo sapiens OX=9606 GN=KCTD17 PE=1 SV=3 5.4 1714 - 955256 - - - -2.1741 - 3.253 0.512 - 427.9 1 2 0 -0.0035 15 0 0 0 1.67E+09 4.01E+08 - - - 7.3253 0.9982 221125_WJC_METTL3_EV_vs_WT_F08.07212.07212.3 0.00271 13/48 K.AQLEQSVEENKER.M sp|Q96SB3|NEB2_HUMAN 1 1558.7587 1.05 112644 7212 3 1558.761068 520.5935 Neurabin-2 OS=Homo sapiens OX=9606 GN=PPP1R9B PE=1 SV=3 4.49 1714.5 - 512375 - - - 1.5102 - 2.281 0.316 - 252.2 1 2 1 0.0024 13 0 0 0 5.60E+06 5.36E+06 - - - 4.2982 1 221125_WJC_METTL3_EV_vs_WT_F08.07214.07214.3 2.76E-07 17/48 K.KAEGEPQEESPLK.S "sp|Q9NYF8|BCLF1_HUMAN,tr|E9PKI6|E9PKI6_HUMAN,tr|A0A1W2PQ43|A0A1W2PQ43_HUMAN,tr|E9PK91|E9PK91_HUMAN,tr|E9PJA7|E9PJA7_HUMAN,tr|E9PK09|E9PK09_HUMAN,tr|E9PQN2|E9PQN2_HUMAN" 7 1440.7096 2.38 112645 7214 3 1440.709226 481.2438 Bcl-2-associated transcription factor 1 OS=Homo sapiens OX=9606 GN=BCLAF1 PE=1 SV=2 4.49 1714.7 - 3.93E+07 - - - -0.2867 - 2.935 0.588 - 612.9 1 2 0 -0.0004 13 0 0 0 3.33E+09 1.40E+09 - - - 8.0148 0.9858 221125_WJC_METTL3_EV_vs_WT_F08.07217.07217.2 0.00954 17/18 L.K[136.11]GDDLQAIK[136.11]K[136.11].E "sp|P07910|HNRPC_HUMAN,tr|B4DY08|B4DY08_HUMAN,tr|G3V5V7|G3V5V7_HUMAN,tr|B2R5W2|B2R5W2_HUMAN,tr|G3V4C1|G3V4C1_HUMAN,tr|G3V576|G3V576_HUMAN,tr|G3V2D6|G3V2D6_HUMAN,tr|G3V4W0|G3V4W0_HUMAN,tr|G3V2Q1|G3V2Q1_HUMAN" 9 1138.6772 2.85 112648 7217 2 1138.674632 570.3459 Heterogeneous nuclear ribonucleoproteins C1\C2 OS=Homo sapiens OX=9606 GN=HNRNPC PE=1 SV=4 8.5 1715.1 - 693938 - - - -2.2754 - 2.699 0.49 - 852.2 1 1 0 -0.0026 10 0 0 0 8.88E+07 3.12E+07 - - - 5.4308 0.9632 221125_WJC_METTL3_EV_vs_WT_F08.07221.07221.3 0.128 May-56 R.HSASTVC[160.03]C[160.03]MAAESSR.M tr|A0A1W2PQ68|A0A1W2PQ68_HUMAN 1 1652.6705 4.24 112650 7221 3 1652.666393 551.8974 Centrosomal protein of 164 kDa (Fragment) OS=Homo sapiens OX=9606 GN=CEP164 PE=1 SV=1 6.73 1715.6 - 614982 - - - -2.4911 - 1.06 0.259 - 26.5 1 2 0 -0.0041 15 0 0 0 1.86E+08 4.40E+07 - - - 1.5785 1 221125_WJC_METTL3_EV_vs_WT_F08.07223.07223.2 9.14E-08 16-Nov K.GDDLQAIKK.E "sp|P07910|HNRPC_HUMAN,tr|B4DY08|B4DY08_HUMAN,tr|G3V5V7|G3V5V7_HUMAN,tr|B2R5W2|B2R5W2_HUMAN,tr|G3V4C1|G3V4C1_HUMAN,tr|G3V576|G3V576_HUMAN,tr|G3V2D6|G3V2D6_HUMAN,tr|G3V4W0|G3V4W0_HUMAN,tr|G3V2Q1|G3V2Q1_HUMAN" 9 986.5397 1.6 112652 7223 2 986.538717 494.2771 Heterogeneous nuclear ribonucleoproteins C1\C2 OS=Homo sapiens OX=9606 GN=HNRNPC PE=1 SV=4 5.96 1715.8 - 2.11E+06 - - - -0.9559 - 2.109 0.628 - 575.3 1 2 0 -0.0009 9 0 0 0 9.70E+07 6.05E+07 - - - 5.8379 0.9993 221125_WJC_METTL3_EV_vs_WT_F08.07228.07228.3 0.000108 Aug-44 K.VMSQNFTNC[160.03]HTK[136.11].L "sp|Q13283|G3BP1_HUMAN,tr|A0A7I2YQB1|A0A7I2YQB1_HUMAN,tr|A0A7I2V5M7|A0A7I2V5M7_HUMAN,tr|E5RH42|E5RH42_HUMAN,tr|A0A7I2V533|A0A7I2V533_HUMAN,tr|A0A7P0P2U7|A0A7P0P2U7_HUMAN,tr|A0A7I2V2S5|A0A7I2V2S5_HUMAN,tr|A0A7I2YQU8|A0A7I2YQU8_HUMAN,tr|E5RJU8|E5RJU8_HUMAN,tr|A0A7I2YQQ8|A0A7I2YQQ8_HUMAN,tr|A0A7I2V651|A0A7I2V651_HUMAN,tr|E5RIF8|E5RIF8_HUMAN,tr|A0A7I2YQN9|A0A7I2YQN9_HUMAN" 13 1473.6584 1.02 112655 7228 3 1473.651459 492.2267 Ras GTPase-activating protein-binding protein 1 OS=Homo sapiens OX=9606 GN=G3BP1 PE=1 SV=1 8.2 1716.5 - 2.46E+06 - - - -4.7229 - 1.969 0.481 - 80.9 1 2 0 -0.007 12 0 0 0 3.28E+08 3.21E+08 - - - 5.7787 0.9986 221125_WJC_METTL3_EV_vs_WT_F08.07229.07229.3 0.0238 Jul-44 K.VMSQNFTNC[160.03]HTK.L "sp|Q13283|G3BP1_HUMAN,tr|A0A7I2YQB1|A0A7I2YQB1_HUMAN,tr|A0A7I2V5M7|A0A7I2V5M7_HUMAN,tr|E5RH42|E5RH42_HUMAN,tr|A0A7I2V533|A0A7I2V533_HUMAN,tr|A0A7P0P2U7|A0A7P0P2U7_HUMAN,tr|A0A7I2V2S5|A0A7I2V2S5_HUMAN,tr|A0A7I2YQU8|A0A7I2YQU8_HUMAN,tr|E5RJU8|E5RJU8_HUMAN,tr|A0A7I2YQQ8|A0A7I2YQQ8_HUMAN,tr|A0A7I2V651|A0A7I2V651_HUMAN,tr|E5RIF8|E5RIF8_HUMAN,tr|A0A7I2YQN9|A0A7I2YQN9_HUMAN" 13 1465.6442 1.02 112656 7229 3 1465.640003 489.5553 Ras GTPase-activating protein-binding protein 1 OS=Homo sapiens OX=9606 GN=G3BP1 PE=1 SV=1 8.2 1716.5 - 2.23E+06 - - - -2.8766 - 1.433 0.396 - 48.7 1 2 0 -0.0042 12 0 0 0 3.28E+08 3.21E+08 - - - 3.9511 1 221125_WJC_METTL3_EV_vs_WT_F08.07231.07231.2 4.35E-09 15/28 K.ELHSTPNGLSSESSR.K "sp|Q8N5Z5|KCD17_HUMAN,tr|A0A087WX35|A0A087WX35_HUMAN,tr|H0Y731|H0Y731_HUMAN" 3 1599.7489 4.25 112658 7231 2 1599.748438 800.8817 BTB\POZ domain-containing protein KCTD17 OS=Homo sapiens OX=9606 GN=KCTD17 PE=1 SV=3 5.4 1716.8 - 644862 - - - -0.275 - 2.723 0.611 - 603 1 2 0 -0.0004 15 0 0 0 9.60E+07 2.26E+07 - - - 6.0165 0.9997 221125_WJC_METTL3_EV_vs_WT_F08.07232.07232.2 3.59E-05 24-Dec K.ISSSLPSGNNNGK.V "sp|Q96CB8|INT12_HUMAN,tr|C9J0M6|C9J0M6_HUMAN,tr|A0A087WXN4|A0A087WXN4_HUMAN,tr|A0A1B0GX90|A0A1B0GX90_HUMAN,tr|E9PGI3|E9PGI3_HUMAN,tr|C9JDP3|C9JDP3_HUMAN" 6 1273.6262 1 112659 7232 2 1273.624361 637.8204 Integrator complex subunit 12 OS=Homo sapiens OX=9606 GN=INTS12 PE=1 SV=1 8.75 1716.9 - 434644 - - - -1.4777 - 2.176 0.447 - 296.2 1 2 0 -0.0019 13 0 0 0 1.20E+08 1.19E+08 - - - 4.3374 1 221125_WJC_METTL3_EV_vs_WT_F08.07237.07237.3 1.17E-08 17/48 R.TVYHAEEVQC[160.03]DGR.S "sp|Q16527|CSRP2_HUMAN,tr|F8VQR7|F8VQR7_HUMAN,tr|F8VW96|F8VW96_HUMAN" 3 1562.6784 0.26 112662 7237 3 1562.677888 521.9001 Cysteine and glycine-rich protein 2 OS=Homo sapiens OX=9606 GN=CSRP2 PE=1 SV=3 4.65 1717.6 - 1.17E+06 - - - -0.2995 - 3.025 0.578 - 428.9 1 2 0 -0.0005 13 0 0 0 7.95E+07 3.11E+08 - - - 7.9852 0.9945 221125_WJC_METTL3_EV_vs_WT_F08.07239.07239.3 0.000107 Dec-36 L.K[136.11]GDDLQAIK[136.11]K[136.11].E "sp|P07910|HNRPC_HUMAN,tr|B4DY08|B4DY08_HUMAN,tr|G3V5V7|G3V5V7_HUMAN,tr|B2R5W2|B2R5W2_HUMAN,tr|G3V4C1|G3V4C1_HUMAN,tr|G3V576|G3V576_HUMAN,tr|G3V2D6|G3V2D6_HUMAN,tr|G3V4W0|G3V4W0_HUMAN,tr|G3V2Q1|G3V2Q1_HUMAN" 9 1138.6772 0.001 112664 7239 3 1138.676074 380.5664 Heterogeneous nuclear ribonucleoproteins C1\C2 OS=Homo sapiens OX=9606 GN=HNRNPC PE=1 SV=4 8.5 1717.6 - 4.71E+06 - - - -1.0091 - 1.949 0.481 - 200.7 1 1 0 -0.0011 10 0 0 0 0.00E+00 1.45E+08 - - - 5.8512 0.8718 221125_WJC_METTL3_EV_vs_WT_F08.07241.07241.2 0.000278 24-Oct R.TVYHAEEVQC[160.03]DGR[166.11].S "sp|Q16527|CSRP2_HUMAN,tr|F8VQR7|F8VQR7_HUMAN,tr|F8VW96|F8VW96_HUMAN" 3 1572.6866 0.19 112666 7241 2 1573.681902 787.3506 Cysteine and glycine-rich protein 2 OS=Homo sapiens OX=9606 GN=CSRP2 PE=1 SV=3 4.65 1717.9 - 404746 - - - 632.8508 - 1.948 0.525 - 287.5 1 2 0 0.9953 13 0 0 0 4.56E+06 2.37E+07 - - - 4.3175 1 221125_WJC_METTL3_EV_vs_WT_F08.07243.07243.2 3.74E-09 19/24 K.KAEGEPQEESPLK.S "sp|Q9NYF8|BCLF1_HUMAN,tr|E9PKI6|E9PKI6_HUMAN,tr|A0A1W2PQ43|A0A1W2PQ43_HUMAN,tr|E9PK91|E9PK91_HUMAN,tr|E9PJA7|E9PJA7_HUMAN,tr|E9PK09|E9PK09_HUMAN,tr|E9PQN2|E9PQN2_HUMAN" 7 1440.7096 2.72 112667 7243 2 1440.708477 721.3621 Bcl-2-associated transcription factor 1 OS=Homo sapiens OX=9606 GN=BCLAF1 PE=1 SV=2 4.49 1718.2 - 4.32E+06 - - - -0.8065 - 3.763 0.675 - 1365.4 1 2 0 -0.0012 13 0 0 0 6.34E+08 2.33E+08 - - - 7.4274 0.9997 221125_WJC_METTL3_EV_vs_WT_F08.07248.07248.2 7.67E-08 28-Dec K.ELHSTPNGLSSESSR[166.11].K "sp|Q8N5Z5|KCD17_HUMAN,tr|A0A087WX35|A0A087WX35_HUMAN,tr|H0Y731|H0Y731_HUMAN" 3 1609.7571 4.25 112670 7248 2 1609.754682 805.8859 BTB\POZ domain-containing protein KCTD17 OS=Homo sapiens OX=9606 GN=KCTD17 PE=1 SV=3 5.4 1718.7 - 497884 - - - -1.5319 - 1.993 0.45 - 327.6 1 2 0 -0.0025 15 0 0 0 9.60E+07 2.26E+07 - - - 4.0594 0.9998 221125_WJC_METTL3_EV_vs_WT_F08.07250.07250.2 2.74E-07 22-Jul K.VMSQNFTNC[160.03]HTK[136.11].L "sp|Q13283|G3BP1_HUMAN,tr|A0A7I2YQB1|A0A7I2YQB1_HUMAN,tr|A0A7I2V5M7|A0A7I2V5M7_HUMAN,tr|E5RH42|E5RH42_HUMAN,tr|A0A7I2V533|A0A7I2V533_HUMAN,tr|A0A7P0P2U7|A0A7P0P2U7_HUMAN,tr|A0A7I2V2S5|A0A7I2V2S5_HUMAN,tr|A0A7I2YQU8|A0A7I2YQU8_HUMAN,tr|E5RJU8|E5RJU8_HUMAN,tr|A0A7I2YQQ8|A0A7I2YQQ8_HUMAN,tr|A0A7I2V651|A0A7I2V651_HUMAN,tr|E5RIF8|E5RIF8_HUMAN,tr|A0A7I2YQN9|A0A7I2YQN9_HUMAN" 13 1473.6584 0.99 112672 7250 2 1473.655054 737.8365 Ras GTPase-activating protein-binding protein 1 OS=Homo sapiens OX=9606 GN=G3BP1 PE=1 SV=1 8.2 1719 - 348571 - - - -2.2834 - 1.925 0.644 - 135.9 1 2 0 -0.0034 12 0 0 0 2.13E+07 2.15E+07 - - - 5.5197 0.9996 221125_WJC_METTL3_EV_vs_WT_F08.07255.07255.2 0.000293 24-Dec K.ISSSLPSGNNNGK[136.11].V "sp|Q96CB8|INT12_HUMAN,tr|C9J0M6|C9J0M6_HUMAN,tr|A0A087WXN4|A0A087WXN4_HUMAN,tr|A0A1B0GX90|A0A1B0GX90_HUMAN,tr|E9PGI3|E9PGI3_HUMAN,tr|C9JDP3|C9JDP3_HUMAN" 6 1281.6404 1 112674 7255 2 1281.6384 641.8275 Integrator complex subunit 12 OS=Homo sapiens OX=9606 GN=INTS12 PE=1 SV=1 8.75 1719.7 - 2.87E+06 - - - -1.5941 - 2.036 0.41 - 301 1 2 0 -0.002 13 0 0 0 1.20E+08 1.19E+08 - - - 3.8934 0.8384 221125_WJC_METTL3_EV_vs_WT_F08.07259.07259.2 0.895 20-Jun K.LK[136.11]GDDLQAIKK[136.11].E "sp|P07910|HNRPC_HUMAN,tr|B4DY08|B4DY08_HUMAN,tr|G3V5V7|G3V5V7_HUMAN,tr|B2R5W2|B2R5W2_HUMAN,tr|G3V4C1|G3V4C1_HUMAN,tr|G3V576|G3V576_HUMAN,tr|G3V2D6|G3V2D6_HUMAN,tr|G3V4W0|G3V4W0_HUMAN,tr|G3V2Q1|G3V2Q1_HUMAN" 9 1243.7471 - 112678 7259 2 1243.747845 622.8808 Heterogeneous nuclear ribonucleoproteins C1\C2 OS=Homo sapiens OX=9606 GN=HNRNPC PE=1 SV=4 8.5 1720.1 - 279949 - - - 0.6094 - 1.083 0.19 - 58.8 5 2 1 0.0008 11 0 0 0 - - - - - 0.3476 0.9896 221125_WJC_METTL3_EV_vs_WT_F08.07265.07265.2 3.15E-05 22-Oct P.GEVAGTVTGQK[136.11]R[166.11].R "sp|Q86U44|MTA70_HUMAN,tr|F5H6D8|F5H6D8_HUMAN,tr|H0YFV6|H0YFV6_HUMAN,tr|B4DTN4|B4DTN4_HUMAN" 4 1219.664 0.02 112682 7265 2 1219.662077 610.8393 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 8.75 1720.9 - 0 - - - -1.5512 - 2.207 0.532 - 394.9 1 1 0 -0.0019 12 0 0 0 2.00E+05 9.88E+06 - - - 5.0527 0.9994 221125_WJC_METTL3_EV_vs_WT_F08.07268.07268.2 0.000312 22-Aug K.VMSQNFTNC[160.03]HTK.L "sp|Q13283|G3BP1_HUMAN,tr|A0A7I2YQB1|A0A7I2YQB1_HUMAN,tr|A0A7I2V5M7|A0A7I2V5M7_HUMAN,tr|E5RH42|E5RH42_HUMAN,tr|A0A7I2V533|A0A7I2V533_HUMAN,tr|A0A7P0P2U7|A0A7P0P2U7_HUMAN,tr|A0A7I2V2S5|A0A7I2V2S5_HUMAN,tr|A0A7I2YQU8|A0A7I2YQU8_HUMAN,tr|E5RJU8|E5RJU8_HUMAN,tr|A0A7I2YQQ8|A0A7I2YQQ8_HUMAN,tr|A0A7I2V651|A0A7I2V651_HUMAN,tr|E5RIF8|E5RIF8_HUMAN,tr|A0A7I2YQN9|A0A7I2YQN9_HUMAN" 13 1465.6442 0.99 112683 7268 2 1465.64879 733.8294 Ras GTPase-activating protein-binding protein 1 OS=Homo sapiens OX=9606 GN=G3BP1 PE=1 SV=1 8.2 1721.3 - 410574 - - - 3.1188 - 1.811 0.564 - 164.7 1 2 0 0.0046 12 0 0 0 2.13E+07 2.15E+07 - - - 4.7679 1 221125_WJC_METTL3_EV_vs_WT_F08.07275.07275.2 1.99E-09 16/24 K.K[136.11]AEGEPQEESPLK[136.11].S "sp|Q9NYF8|BCLF1_HUMAN,tr|E9PKI6|E9PKI6_HUMAN,tr|A0A1W2PQ43|A0A1W2PQ43_HUMAN,tr|E9PK91|E9PK91_HUMAN,tr|E9PJA7|E9PJA7_HUMAN,tr|E9PK09|E9PK09_HUMAN,tr|E9PQN2|E9PQN2_HUMAN" 7 1456.738 2.71 112687 7275 2 1456.737135 729.3763 Bcl-2-associated transcription factor 1 OS=Homo sapiens OX=9606 GN=BCLAF1 PE=1 SV=2 4.49 1722.1 - 719889 - - - -0.6206 - 3.342 0.562 - 728.5 1 2 0 -0.0009 13 0 0 0 6.30E+08 2.32E+08 - - - 6.2883 0.9998 221125_WJC_METTL3_EV_vs_WT_F08.07277.07277.2 2.42E-06 24-Oct R.TVYHAEEVQC[160.03]DGR.S "sp|Q16527|CSRP2_HUMAN,tr|F8VQR7|F8VQR7_HUMAN,tr|F8VW96|F8VW96_HUMAN" 3 1562.6784 0.19 112688 7277 2 1562.675571 782.3465 Cysteine and glycine-rich protein 2 OS=Homo sapiens OX=9606 GN=CSRP2 PE=1 SV=3 4.65 1722.3 - 130595 - - - -1.7822 - 2.032 0.639 - 323.1 1 2 0 -0.0028 13 0 0 0 4.56E+06 2.36E+07 - - - 5.5795 0.873 221125_WJC_METTL3_EV_vs_WT_F08.07285.07285.2 3.42 12-Jun K.GGEIVHR.K tr|D6R924|D6R924_HUMAN 1 766.4086 1.08 112693 7285 2 766.410098 384.2116 Gamma-aminobutyric acid receptor subunit alpha-4 OS=Homo sapiens OX=9606 GN=GABRA4 PE=4 SV=1 6.75 1723.2 - 359118 - - - 1.9728 - 1.185 0 - 150.7 2 2 0 0.0015 7 0 0 0 1.60E+07 1.48E+07 - - - -0.5561 0.9056 221125_WJC_METTL3_EV_vs_WT_F08.07297.07297.2 2.22 22-Jun K.HLIPAANTGESK.V sp|P62258|1433E_HUMAN 1 1236.6463 3.86 112701 7297 2 1236.646657 619.3304 14-3-3 protein epsilon OS=Homo sapiens OX=9606 GN=YWHAE PE=1 SV=1 6.75 1724.8 - 187283 - - - 0.3291 - 0.998 0.018 - 101.6 1 2 0 0.0004 12 0 0 0 5.49E+06 1.42E+06 - - - -0.8314 0.9929 221125_WJC_METTL3_EV_vs_WT_F08.07303.07303.3 0.704 Oct-32 K.EK[136.11]YEITEQR[166.11].K sp|Q02878|RL6_HUMAN 1 1212.6105 0.85 112704 7303 3 1212.611358 405.2108 60S ribosomal protein L6 OS=Homo sapiens OX=9606 GN=RPL6 PE=1 SV=3 4.79 1725.6 - 1.01E+06 - - - 0.6771 - 1.917 0.224 - 157.6 1 2 1 0.0008 9 0 0 0 3.69E+07 4.37E+07 - - - 2.9984 1 221125_WJC_METTL3_EV_vs_WT_F08.07305.07305.3 8.01E-07 15/52 K.GPGEVAGTVTGQK[136.11]R.R "sp|Q86U44|MTA70_HUMAN,tr|F5H6D8|F5H6D8_HUMAN,tr|H0YFV6|H0YFV6_HUMAN,tr|B4DTN4|B4DTN4_HUMAN" 4 1363.7299 - 112706 7305 3 1363.729298 455.5839 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 8.75 1725.8 - 1.15E+06 - - - -0.4612 - 2.93 0.529 - 352.8 1 2 0 -0.0006 14 0 0 0 - - - - - 7.2945 0.9966 221125_WJC_METTL3_EV_vs_WT_F08.07310.07310.3 0.00109 Sep-56 R.TVVDSEGRTETTVTR.H "sp|O00165|HAX1_HUMAN,tr|Q5VYD6|Q5VYD6_HUMAN,tr|E9PIQ7|E9PIQ7_HUMAN" 3 1649.822 1.36 112709 7310 3 1649.822445 550.948 HCLS1-associated protein X-1 OS=Homo sapiens OX=9606 GN=HAX1 PE=1 SV=2 4.68 1726.4 - 1.83E+06 - - - 0.2437 - 1.44 0.362 - 54.5 1 2 1 0.0004 15 0 0 0 3.44E+07 2.52E+07 - - - 3.5273 0.8555 221125_WJC_METTL3_EV_vs_WT_F08.07313.07313.4 0.21 May-84 R.HSASTVC[160.03]C[160.03]MAAESSR.M tr|A0A1W2PQ68|A0A1W2PQ68_HUMAN 1 1652.6705 4.11 112712 7313 4 1652.66434 414.1749 Centrosomal protein of 164 kDa (Fragment) OS=Homo sapiens OX=9606 GN=CEP164 PE=1 SV=1 6.73 1726.6 - 1.60E+06 - - - -3.7334 - 1.165 0.172 - 23.4 1 2 0 -0.0062 15 0 0 0 1.19E+08 2.90E+07 - - - 0.776 0.9999 221125_WJC_METTL3_EV_vs_WT_F08.07315.07315.2 8.97E-07 20-Oct K.DSYVGDEAQSK[136.11].R "sp|P63261|ACTG_HUMAN,sp|P68133|ACTS_HUMAN,sp|P62736|ACTA_HUMAN,sp|P68032|ACTC_HUMAN,sp|P60709|ACTB_HUMAN,sp|P63267|ACTH_HUMAN,tr|A0A804GS07|A0A804GS07_HUMAN,tr|I3L3I0|I3L3I0_HUMAN,tr|G5E9R0|G5E9R0_HUMAN,tr|E7EVS6|E7EVS6_HUMAN,tr|A0A6Q8PFE4|A0A6Q8PFE4_HUMAN,tr|B8ZZJ2|B8ZZJ2_HUMAN,tr|J3KT65|J3KT65_HUMAN,tr|I3L3R2|I3L3R2_HUMAN,tr|K7EM38|K7EM38_HUMAN,tr|F6QUT6|F6QUT6_HUMAN,tr|C9JTX5|C9JTX5_HUMAN,tr|A0A6Q8PH58|A0A6Q8PH58_HUMAN,tr|F6UVQ4|F6UVQ4_HUMAN,tr|F8WB63|F8WB63_HUMAN,tr|I3L1U9|I3L1U9_HUMAN,tr|A0A804HKV3|A0A804HKV3_HUMAN,tr|A0A2R8Y793|A0A2R8Y793_HUMAN,tr|I3L4N8|I3L4N8_HUMAN,tr|C9JUM1|C9JUM1_HUMAN,tr|C9JZR7|C9JZR7_HUMAN,tr|C9JFL5|C9JFL5_HUMAN,tr|A0A2R8YGF8|A0A2R8YGF8_HUMAN,tr|A6NL76|A6NL76_HUMAN" 29 1205.5292 0.04 112714 7315 2 1205.529366 603.7719 "Actin, cytoplasmic 2 OS=Homo sapiens OX=9606 GN=ACTG1 PE=1 SV=1" 4.03 1726.8 - 425237 - - - 0.17 - 2.02 0.544 - 213.6 1 2 0 0.0002 11 0 0 0 5.43E+05 1.40E+07 - - - 4.961 0.9885 221125_WJC_METTL3_EV_vs_WT_F08.07316.07316.2 0.00833 16-Aug K.ENVKDYYQK.W "sp|P09234|RU1C_HUMAN,tr|A0A0A0MRR7|A0A0A0MRR7_HUMAN" 2 1185.5666 1.34 112715 7316 2 1185.568832 593.7906 U1 small nuclear ribonucleoprotein C OS=Homo sapiens OX=9606 GN=SNRPC PE=1 SV=1 6.17 1727 - 300766 - - - 1.8801 - 1.517 0.381 - 184.5 1 2 1 0.0022 9 0 0 0 9.09E+06 6.78E+06 - - - 3.06 0.9999 221125_WJC_METTL3_EV_vs_WT_F08.07319.07319.3 1.08E-05 13/44 K.SKAEAESLYQSK.Y sp|P04264|K2C1_HUMAN 1 1339.662 264.32 112717 7319 3 1339.662249 447.5613 "Keratin, type II cytoskeletal 1 OS=Homo sapiens OX=9606 GN=KRT1 PE=1 SV=6" 5.86 1727.3 - 9.37E+06 - - - 0.2157 - 2.683 0.493 - 308.3 1 2 1 0.0003 12 0 0 0 6.88E+08 2.60E+06 - - - 6.772 0.9542 221125_WJC_METTL3_EV_vs_WT_F08.07321.07321.2 0.00188 16-Sep K.ENVK[136.11]DYYQK[136.11].W "sp|P09234|RU1C_HUMAN,tr|A0A0A0MRR7|A0A0A0MRR7_HUMAN" 2 1201.595 1.34 112718 7321 2 1201.598429 601.8048 U1 small nuclear ribonucleoprotein C OS=Homo sapiens OX=9606 GN=SNRPC PE=1 SV=1 6.17 1727.5 - 495386 - - - 2.8512 - 1.661 0.248 - 209 1 2 1 0.0034 9 0 0 0 9.09E+06 6.78E+06 - - - 2.3396 0.9997 221125_WJC_METTL3_EV_vs_WT_F08.07322.07322.2 0.00105 28-Dec R.WSSGVGGSGGGSSGR[166.11].S "sp|O95071|UBR5_HUMAN,tr|E7EMW7|E7EMW7_HUMAN" 2 1303.5781 3.34 112719 7322 2 1303.580779 652.7963 E3 ubiquitin-protein ligase UBR5 OS=Homo sapiens OX=9606 GN=UBR5 PE=1 SV=2 9.75 1727.6 - 377332 - - - 2.085 - 2.117 0.519 - 158.9 1 2 0 0.0027 15 0 0 0 3.60E+07 1.08E+07 - - - 4.7174 0.9992 221125_WJC_METTL3_EV_vs_WT_F08.07325.07325.2 0.0103 20-Jul K.KAAEFNSNLNR.E "sp|Q8WUB8|PHF10_HUMAN,tr|S5FZ81|S5FZ81_HUMAN" 2 1262.6367 5.11 112722 7325 2 1262.638716 632.3257 PHD finger protein 10 OS=Homo sapiens OX=9606 GN=PHF10 PE=1 SV=3 8.75 1728 - 131618 - - - 1.5586 - 1.625 0.384 - 188.8 1 2 0 0.002 11 0 0 0 2.59E+06 5.08E+05 - - - 3.19 1 221125_WJC_METTL3_EV_vs_WT_F08.07327.07327.2 4.07E-08 16/22 K.SKAEAESLYQSK.Y sp|P04264|K2C1_HUMAN 1 1339.662 999 112723 7327 2 1339.662457 670.8383 "Keratin, type II cytoskeletal 1 OS=Homo sapiens OX=9606 GN=KRT1 PE=1 SV=6" 5.86 1728.3 - 1.61E+06 - - - 0.371 - 2.902 0.667 - 544.8 1 2 1 0.0005 12 0 0 0 1.75E+08 0.00E+00 - - - 6.7706 1 221125_WJC_METTL3_EV_vs_WT_F08.07328.07328.2 8.30E-08 22/26 K.K[136.11]GPGEVAGTVTGQK[136.11].R "sp|Q86U44|MTA70_HUMAN,tr|F5H6D8|F5H6D8_HUMAN,tr|H0YFV6|H0YFV6_HUMAN,tr|B4DTN4|B4DTN4_HUMAN" 4 1343.738 0.001 112724 7328 2 1343.737292 672.8763 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 8.59 1728.4 - 1.68E+06 - - - -0.5113 - 3.923 0.584 - 1343 1 2 0 -0.0007 14 0 0 0 0.00E+00 1.18E+08 - - - 6.7843 0.9971 221125_WJC_METTL3_EV_vs_WT_F08.07330.07330.2 0.257 14-Aug R.RPTWAEER.R "sp|Q8ND56|LS14A_HUMAN,tr|A0A096LP11|A0A096LP11_HUMAN,tr|A0A140TA76|A0A140TA76_HUMAN,tr|A0A0G2JQ95|A0A0G2JQ95_HUMAN" 4 1043.5148 0.94 112726 7330 2 1043.513833 522.7647 Protein LSM14 homolog A OS=Homo sapiens OX=9606 GN=LSM14A PE=1 SV=3 6.14 1728.6 - 524219 - - - -0.9669 - 1.808 0.107 - 206.7 1 2 0 -0.001 8 0 0 0 2.10E+07 2.23E+07 - - - 1.6171 0.9986 221125_WJC_METTL3_EV_vs_WT_F08.07336.07336.2 0.000475 20-Jul K.ENAGEDPGLAR.Q sp|P81605|DCD_HUMAN 1 1127.5207 205.28 112730 7336 2 1127.523672 564.7676 Dermcidin OS=Homo sapiens OX=9606 GN=DCD PE=1 SV=2 4.14 1729.4 - 300945 - - - 2.6217 - 1.479 0.429 - 116.5 1 2 0 0.003 11 0 0 0 9.37E+06 4.56E+04 - - - 3.2674 1 221125_WJC_METTL3_EV_vs_WT_F08.07342.07342.2 2.05E-12 16/38 K.EAAGTTAAAGTGGATEQPPR.H "sp|O43290|SNUT1_HUMAN,tr|E9PQI8|E9PQI8_HUMAN" 2 1812.8602 2.78 112734 7342 2 1812.860985 907.4374 U4\U6.U5 tri-snRNP-associated protein 1 OS=Homo sapiens OX=9606 GN=SART1 PE=1 SV=1 4.53 1730.2 - 291348 - - - 0.4225 - 3.07 0.693 - 634.4 1 2 0 0.0008 20 0 0 0 2.27E+07 8.16E+06 - - - 6.917 1 221125_WJC_METTL3_EV_vs_WT_F08.07344.07344.3 8.33E-05 14/48 K.VNEIVETNR[166.11]PDSK[136.11].N sp|Q15008|PSMD6_HUMAN 1 1517.7805 0.8 112735 7344 3 1517.782669 506.9341 26S proteasome non-ATPase regulatory subunit 6 OS=Homo sapiens OX=9606 GN=PSMD6 PE=1 SV=1 4.68 1730.4 - 1.46E+06 - - - 1.4581 - 2.889 0.444 - 313.2 1 2 0 0.0022 13 0 0 0 3.01E+07 3.77E+07 - - - 6.366 0.9999 221125_WJC_METTL3_EV_vs_WT_F08.07349.07349.3 0.0552 Nov-48 K.VNEIVETNRPDSK.N sp|Q15008|PSMD6_HUMAN 1 1499.758 0.62 112737 7349 3 1499.759085 500.9266 26S proteasome non-ATPase regulatory subunit 6 OS=Homo sapiens OX=9606 GN=PSMD6 PE=1 SV=1 4.68 1731 - 1.05E+06 - - - 0.7328 - 2.411 0.368 - 241.1 1 2 0 0.0011 13 0 0 0 2.29E+07 3.70E+07 - - - 5.0286 1 221125_WJC_METTL3_EV_vs_WT_F08.07350.07350.3 2.31E-08 18/76 K.EAAGTTAAAGTGGATEQPPR.H "sp|O43290|SNUT1_HUMAN,tr|E9PQI8|E9PQI8_HUMAN" 2 1812.8602 2.96 112738 7350 3 1812.863494 605.294 U4\U6.U5 tri-snRNP-associated protein 1 OS=Homo sapiens OX=9606 GN=SART1 PE=1 SV=1 4.53 1731.1 - 879882 - - - 1.8065 - 3.247 0.588 - 368.1 1 2 0 0.0033 20 0 0 0 3.16E+07 1.07E+07 - - - 7.9519 0.9985 221125_WJC_METTL3_EV_vs_WT_F08.07351.07351.3 2.01E-07 14/40 R.SNQLFNGHGGH.L "sp|P78344|IF4G2_HUMAN,tr|H0Y3P2|H0Y3P2_HUMAN,tr|H0YCH5|H0YCH5_HUMAN,tr|D3DQV9|D3DQV9_HUMAN" 4 1166.5217 - 112739 7351 3 1166.522556 389.8478 Eukaryotic translation initiation factor 4 gamma 2 OS=Homo sapiens OX=9606 GN=EIF4G2 PE=1 SV=1 6.66 1731.2 - 470197 - - - 0.7175 - 2.707 0.558 - 340.3 1 1 0 0.0008 11 0 0 0 - - - - - 7.5899 0.929 221125_WJC_METTL3_EV_vs_WT_F08.07352.07352.2 0.185 18-Jun R.ADILEDK[136.11]DGK[136.11].S "sp|P52272|HNRPM_HUMAN,tr|M0R019|M0R019_HUMAN,tr|M0R0N3|M0R0N3_HUMAN,tr|A0A087X0X3|A0A087X0X3_HUMAN,tr|M0QZM1|M0QZM1_HUMAN,tr|M0QYQ7|M0QYQ7_HUMAN,tr|M0R2T0|M0R2T0_HUMAN" 7 1118.579 2.71 112740 7352 2 1118.579744 560.2968 Heterogeneous nuclear ribonucleoprotein M OS=Homo sapiens OX=9606 GN=HNRNPM PE=1 SV=3 4.23 1731.4 - 132840 - - - 0.6481 - 1.111 0.223 - 77.5 1 2 1 0.0007 10 0 0 0 4.47E+06 1.65E+06 - - - 0.9817 0.9971 221125_WJC_METTL3_EV_vs_WT_F08.07355.07355.3 0.000484 Sep-40 K.KAAEFNSNLNR.E "sp|Q8WUB8|PHF10_HUMAN,tr|S5FZ81|S5FZ81_HUMAN" 2 1262.6367 9.1 112742 7355 3 1262.642218 421.8862 PHD finger protein 10 OS=Homo sapiens OX=9606 GN=PHF10 PE=1 SV=3 8.75 1731.7 - 374167 - - - 4.3322 - 1.585 0.396 - 136.7 1 2 0 0.0055 11 0 0 0 3.35E+07 3.68E+06 - - - 4.2619 0.9986 221125_WJC_METTL3_EV_vs_WT_F08.07357.07357.3 0.0016 13/52 R.AQTSGIEEETVKEK.K "sp|P55197|AF10_HUMAN,tr|Q5JT35|Q5JT35_HUMAN,tr|H0Y5P4|H0Y5P4_HUMAN" 3 1547.7679 5.62 112743 7357 3 1547.766543 516.9299 Protein AF-10 OS=Homo sapiens OX=9606 GN=MLLT10 PE=1 SV=2 4.49 1731.9 - 840684 - - - -0.8651 - 2.163 0.325 - 247.7 1 2 1 -0.0013 14 0 0 0 2.89E+07 5.15E+06 - - - 4.2133 0.9999 221125_WJC_METTL3_EV_vs_WT_F08.07363.07363.3 0.000225 Nov-44 R.SHISDQSPLSSK.R sp|P42166|LAP2A_HUMAN 1 1284.631 0.84 112747 7363 3 1284.633275 429.2176 "Lamina-associated polypeptide 2, isoform alpha OS=Homo sapiens OX=9606 GN=TMPO PE=1 SV=2" 6.46 1732.7 - 801688 - - - 1.7756 - 2.041 0.449 - 164.7 1 2 0 0.0023 12 0 0 0 5.42E+07 6.42E+07 - - - 5.5228 1 221125_WJC_METTL3_EV_vs_WT_F08.07367.07367.2 3.15E-10 15/38 K.EAAGTTAAAGTGGATEQPPR[166.11].H "sp|O43290|SNUT1_HUMAN,tr|E9PQI8|E9PQI8_HUMAN" 2 1822.8685 2.78 112751 7367 2 1822.86914 912.4415 U4\U6.U5 tri-snRNP-associated protein 1 OS=Homo sapiens OX=9606 GN=SART1 PE=1 SV=1 4.53 1733.3 - 258966 - - - 0.3571 - 3.081 0.676 - 608.9 1 2 0 0.0007 20 0 0 0 2.27E+07 8.16E+06 - - - 6.8002 1 221125_WJC_METTL3_EV_vs_WT_F08.07370.07370.3 4.49E-12 22/52 K.GPGEVAGTVTGQK[136.11]R[166.11].R "sp|Q86U44|MTA70_HUMAN,tr|F5H6D8|F5H6D8_HUMAN,tr|H0YFV6|H0YFV6_HUMAN,tr|B4DTN4|B4DTN4_HUMAN" 4 1373.7382 0.02 112752 7370 3 1373.740619 458.92 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 8.75 1733.7 - 4.27E+07 - - - 1.7631 - 3.92 0.658 - 833.8 1 2 0 0.0024 14 0 0 0 4.51E+07 1.95E+09 - - - 9.5058 0.995 221125_WJC_METTL3_EV_vs_WT_F08.07372.07372.3 0.00824 Aug-40 R.ESAINVAEGKK.Q "sp|Q9UJZ1|STML2_HUMAN,tr|A0A087WYB4|A0A087WYB4_HUMAN,tr|F2Z2I8|F2Z2I8_HUMAN" 3 1144.6088 1.2 112754 7372 3 1144.610915 382.5435 "Stomatin-like protein 2, mitochondrial OS=Homo sapiens OX=9606 GN=STOML2 PE=1 SV=1" 6.24 1733.9 - 737517 - - - 1.846 - 1.322 0.293 - 66.1 1 2 0 0.0021 11 0 0 0 1.15E+07 9.61E+06 - - - 2.5991 0.9994 221125_WJC_METTL3_EV_vs_WT_F08.07373.07373.2 1.36E-05 28-Oct K.VVNANQNASPNVPGK.R "sp|Q8IWI9|MGAP_HUMAN,tr|H3BP52|H3BP52_HUMAN" 2 1507.7743 1.45 112755 7373 2 1507.778722 754.8944 MAX gene-associated protein OS=Homo sapiens OX=9606 GN=MGA PE=1 SV=4 8.72 1734.1 - 130763 - - - 2.9295 - 1.934 0.553 - 180 1 2 0 0.0044 15 0 0 0 5.87E+06 4.04E+06 - - - 4.7457 1 221125_WJC_METTL3_EV_vs_WT_F08.07375.07375.2 8.36E-08 15/26 K.GPGEVAGTVTGQK[136.11]R[166.11].R "sp|Q86U44|MTA70_HUMAN,tr|F5H6D8|F5H6D8_HUMAN,tr|H0YFV6|H0YFV6_HUMAN,tr|B4DTN4|B4DTN4_HUMAN" 4 1373.7382 0.001 112756 7375 2 1373.739842 687.8764 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 8.75 1734.3 - 4.73E+06 - - - 1.1975 - 3.058 0.641 - 730.2 1 2 0 0.0016 14 0 0 0 0.00E+00 2.64E+08 - - - 6.5799 0.9999 221125_WJC_METTL3_EV_vs_WT_F08.07377.07377.3 0.000877 Nov-48 K.K[136.11]AEGEPQEESPLK[136.11].S "sp|Q9NYF8|BCLF1_HUMAN,tr|E9PKI6|E9PKI6_HUMAN,tr|A0A1W2PQ43|A0A1W2PQ43_HUMAN,tr|E9PK91|E9PK91_HUMAN,tr|E9PJA7|E9PJA7_HUMAN,tr|E9PK09|E9PK09_HUMAN,tr|E9PQN2|E9PQN2_HUMAN" 7 1456.738 2.38 112757 7377 3 1456.739056 486.5866 Bcl-2-associated transcription factor 1 OS=Homo sapiens OX=9606 GN=BCLAF1 PE=1 SV=2 4.49 1734.5 - 737693 - - - 0.6981 - 2.317 0.415 - 183.2 1 2 0 0.001 13 0 0 0 3.34E+09 1.40E+09 - - - 5.4448 0.9924 221125_WJC_METTL3_EV_vs_WT_F08.07378.07378.2 1.42E-05 20-Sep R.SNQLFNGHGGH.L "sp|P78344|IF4G2_HUMAN,tr|H0Y3P2|H0Y3P2_HUMAN,tr|H0YCH5|H0YCH5_HUMAN,tr|D3DQV9|D3DQV9_HUMAN" 4 1166.5217 - 112758 7378 2 1166.520449 584.2681 Eukaryotic translation initiation factor 4 gamma 2 OS=Homo sapiens OX=9606 GN=EIF4G2 PE=1 SV=1 6.66 1734.7 - 239156 - - - -1.0887 - 1.955 0.585 - 330 1 1 0 -0.0013 11 0 0 0 - - - - - 5.175 0.9943 221125_WJC_METTL3_EV_vs_WT_F08.07380.07380.3 7.79E-08 14/60 A.ASYAAQQHPQAAASYR.G sp|Q96PK6|RBM14_HUMAN 1 1718.8125 2.24 112760 7380 3 1718.817301 573.9448 RNA-binding protein 14 OS=Homo sapiens OX=9606 GN=RBM14 PE=1 SV=2 8.64 1734.8 - 334169 - - - 2.8043 - 2.542 0.578 - 169.9 1 1 0 0.0048 16 0 0 0 1.21E+07 5.39E+06 - - - 7.3766 0.9998 221125_WJC_METTL3_EV_vs_WT_F08.07386.07386.3 0.000146 Dec-40 K.LK[136.11]GDDLQAIK[136.11]K[136.11].E "sp|P07910|HNRPC_HUMAN,tr|B4DY08|B4DY08_HUMAN,tr|G3V5V7|G3V5V7_HUMAN,tr|B2R5W2|B2R5W2_HUMAN,tr|G3V4C1|G3V4C1_HUMAN,tr|G3V576|G3V576_HUMAN,tr|G3V2D6|G3V2D6_HUMAN,tr|G3V4W0|G3V4W0_HUMAN,tr|G3V2Q1|G3V2Q1_HUMAN" 9 1251.7613 1.37 112764 7386 3 1251.76169 418.261 Heterogeneous nuclear ribonucleoproteins C1\C2 OS=Homo sapiens OX=9606 GN=HNRNPC PE=1 SV=4 8.5 1735.6 - 1.10E+06 - - - 0.3219 - 2.237 0.476 - 104.7 1 2 1 0.0004 11 0 0 0 6.60E+09 4.81E+09 - - - 6.1341 0.9929 221125_WJC_METTL3_EV_vs_WT_F08.07387.07387.3 4.64E-06 Dec-48 G.PGEVAGTVTGQK[136.11]R[166.11].R "sp|Q86U44|MTA70_HUMAN,tr|F5H6D8|F5H6D8_HUMAN,tr|H0YFV6|H0YFV6_HUMAN,tr|B4DTN4|B4DTN4_HUMAN" 4 1316.7167 0.2 112765 7387 3 1316.718004 439.9129 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 9.18 1735.8 - 331049 - - - 0.9653 - 2.077 0.462 - 176.9 1 1 0 0.0013 13 0 0 0 3.55E+06 1.81E+07 - - - 5.6722 0.9894 221125_WJC_METTL3_EV_vs_WT_F08.07388.07388.3 0.0193 Oct-36 R.TKEEINELNR.M "sp|Q14533|KRT81_HUMAN,sp|A6NCN2|KR87P_HUMAN,sp|P78386|KRT85_HUMAN,sp|O43790|KRT86_HUMAN,sp|P78385|KRT83_HUMAN,tr|A0A087X106|A0A087X106_HUMAN,tr|F5GYI5|F5GYI5_HUMAN" 7 1244.6361 28.65 112766 7388 3 1244.638212 415.886 "Keratin, type II cuticular Hb1 OS=Homo sapiens OX=9606 GN=KRT81 PE=1 SV=3" 4.78 1735.9 - 391740 - - - 1.713 - 1.818 0.249 - 213.2 1 2 1 0.0021 10 0 0 0 3.45E+07 1.20E+06 - - - 3.0612 0.9992 221125_WJC_METTL3_EV_vs_WT_F08.07394.07394.3 0.00105 Oct-44 K.DLETRPTQHELR.L "sp|Q8NHQ1|CEP70_HUMAN,tr|B7Z2D2|B7Z2D2_HUMAN,tr|C9J966|C9J966_HUMAN" 3 1493.7587 0.88 112770 7394 3 1493.755389 498.9268 Centrosomal protein of 70 kDa OS=Homo sapiens OX=9606 GN=CEP70 PE=1 SV=2 5.45 1736.7 - 735186 - - - -2.1858 - 1.87 0.34 - 114.5 1 2 0 -0.0033 12 0 0 0 1.12E+07 1.27E+07 - - - 4.0648 0.9853 221125_WJC_METTL3_EV_vs_WT_F08.07395.07395.3 2.63E-05 Nov-60 A.ASYAAQQHPQAAASYR[166.11].G sp|Q96PK6|RBM14_HUMAN 1 1728.8208 2.24 112771 7395 3 1728.823434 577.2809 RNA-binding protein 14 OS=Homo sapiens OX=9606 GN=RBM14 PE=1 SV=2 8.64 1736.8 - 152264 - - - 1.5519 - 1.904 0.452 - 90.4 1 1 0 0.0027 16 0 0 0 1.21E+07 5.39E+06 - - - 5.2309 1 221125_WJC_METTL3_EV_vs_WT_F08.07397.07397.2 6.30E-08 30-Oct K.FSPGAPGGSGSQPNQK.L "sp|Q15942|ZYX_HUMAN,tr|H7C3D3|H7C3D3_HUMAN,tr|H0Y2Y8|H0Y2Y8_HUMAN" 3 1514.7114 3.6 112773 7397 2 1514.713856 758.363 Zyxin OS=Homo sapiens OX=9606 GN=ZYX PE=1 SV=1 8.75 1737.1 - 228413 - - - 1.6412 - 2.22 0.655 - 181.3 1 2 0 0.0025 16 0 0 0 1.52E+08 4.23E+07 - - - 5.8388 0.9355 221125_WJC_METTL3_EV_vs_WT_F08.07404.07404.3 0.21 Aug-56 K.ATSSATTAAAPTLRR.L "sp|Q8N9M1|CS047_HUMAN,tr|J3QS80|J3QS80_HUMAN,tr|A0A2R8Y6U9|A0A2R8Y6U9_HUMAN,tr|A0A804HLH2|A0A804HLH2_HUMAN" 4 1473.79 3.43 112777 7404 3 1473.793472 492.2706 Uncharacterized protein C19orf47 OS=Homo sapiens OX=9606 GN=C19orf47 PE=1 SV=1 12 1738 - 382431 - - - 2.3864 - 1.563 0.136 - 63.9 1 2 0 0.0035 15 0 0 0 1.22E+07 3.56E+06 - - - 1.2207 0.9997 221125_WJC_METTL3_EV_vs_WT_F08.07408.07408.2 0.000283 22-Jun R.TENDQEISEDTR[166.11].S "sp|P17036|ZNF3_HUMAN,tr|C9JK31|C9JK31_HUMAN,tr|C9J5S8|C9J5S8_HUMAN,tr|Q86U76|Q86U76_HUMAN" 4 1445.6146 2.07 112779 7408 2 1445.613684 723.8146 Zinc finger protein 3 OS=Homo sapiens OX=9606 GN=ZNF3 PE=1 SV=3 3.83 1738.6 - 67482.5 - - - -0.6101 - 1.402 0.484 - 113.4 1 2 0 -0.0009 12 0 0 0 1.62E+06 7.82E+05 - - - 3.5046 0.998 221125_WJC_METTL3_EV_vs_WT_F08.07410.07410.3 0.00143 Nov-52 R.NVIHASDSVEGAQR[166.11].E "sp|O00746|NDKM_HUMAN,tr|Q4TT34|Q4TT34_HUMAN,tr|A0A087WVT9|A0A087WVT9_HUMAN,tr|F2Z2X0|F2Z2X0_HUMAN" 4 1491.7305 2.15 112780 7410 3 1491.735695 498.2508 "Nucleoside diphosphate kinase, mitochondrial OS=Homo sapiens OX=9606 GN=NME4 PE=1 SV=1" 5.32 1738.8 - 746122 - - - 3.4564 - 2.199 0.308 - 139.7 1 2 0 0.0052 14 0 0 0 1.47E+10 6.81E+09 - - - 4.0666 0.9992 221125_WJC_METTL3_EV_vs_WT_F08.07411.07411.3 0.0464 Dec-40 R.LHLK[136.11]EPPPPGR[166.11].Q sp|Q12948|FOXC1_HUMAN 1 1257.7313 12.66 112781 7411 3 1257.732478 420.251 Forkhead box protein C1 OS=Homo sapiens OX=9606 GN=FOXC1 PE=1 SV=3 8.75 1739 - 344233 - - - 0.9676 - 2.506 0.325 - 302.3 1 2 1 0.0012 11 0 0 0 8.19E+08 6.47E+07 - - - 4.7729 1 221125_WJC_METTL3_EV_vs_WT_F08.07414.07414.3 7.03E-07 17/52 R.NVIHASDSVEGAQR.E "sp|O00746|NDKM_HUMAN,tr|Q4TT34|Q4TT34_HUMAN,tr|A0A087WVT9|A0A087WVT9_HUMAN,tr|F2Z2X0|F2Z2X0_HUMAN" 4 1481.7223 2.15 112782 7414 3 1481.724211 494.9147 "Nucleoside diphosphate kinase, mitochondrial OS=Homo sapiens OX=9606 GN=NME4 PE=1 SV=1" 5.32 1739.3 - 2.12E+06 - - - 1.3106 - 3.107 0.598 - 327.7 1 2 0 0.0019 14 0 0 0 1.47E+10 6.81E+09 - - - 8.2193 0.9995 221125_WJC_METTL3_EV_vs_WT_F08.07415.07415.2 0.00296 30-Jun K.FSPGAPGGSGSQPNQK[136.11].L "sp|Q15942|ZYX_HUMAN,tr|H7C3D3|H7C3D3_HUMAN,tr|H0Y2Y8|H0Y2Y8_HUMAN" 3 1522.7256 3.6 112783 7415 2 1522.724964 762.3701 Zyxin OS=Homo sapiens OX=9606 GN=ZYX PE=1 SV=1 8.75 1739.5 - 186585 - - - -0.398 - 1.378 0.434 - 51.6 1 2 0 -0.0006 16 0 0 0 1.53E+08 4.23E+07 - - - 3.0346 1 221125_WJC_METTL3_EV_vs_WT_F08.07416.07416.2 2.00E-08 26-Dec R.NVIHASDSVEGAQR.E "sp|O00746|NDKM_HUMAN,tr|Q4TT34|Q4TT34_HUMAN,tr|A0A087WVT9|A0A087WVT9_HUMAN,tr|F2Z2X0|F2Z2X0_HUMAN" 4 1481.7223 2.05 112784 7416 2 1481.7232 741.8684 "Nucleoside diphosphate kinase, mitochondrial OS=Homo sapiens OX=9606 GN=NME4 PE=1 SV=1" 5.32 1739.6 - 238110 - - - 0.6283 - 2.523 0.659 - 491.3 1 2 0 0.0009 14 0 0 0 2.56E+09 1.25E+09 - - - 6.2304 0.9772 221125_WJC_METTL3_EV_vs_WT_F08.07417.07417.2 0.00229 20-Aug R.DR[166.11]GSDVESLDK[136.11].L "sp|Q96TA2|YMEL1_HUMAN,tr|Q96I63|Q96I63_HUMAN,tr|Q5T8D1|Q5T8D1_HUMAN,tr|Q5T8D2|Q5T8D2_HUMAN,tr|R4GNA5|R4GNA5_HUMAN" 5 1237.5905 1.46 112785 7417 2 1237.59353 619.8025 ATP-dependent zinc metalloprotease YME1L1 OS=Homo sapiens OX=9606 GN=YME1L1 PE=1 SV=2 4.23 1739.7 - 177539 - - - 2.4241 - 1.782 0.287 - 164.1 1 2 1 0.003 11 0 0 0 8.50E+06 5.80E+06 - - - 2.7228 0.9999 221125_WJC_METTL3_EV_vs_WT_F08.07418.07418.2 0.0137 26-Oct R.NVIHASDSVEGAQR[166.11].E "sp|O00746|NDKM_HUMAN,tr|Q4TT34|Q4TT34_HUMAN,tr|A0A087WVT9|A0A087WVT9_HUMAN,tr|F2Z2X0|F2Z2X0_HUMAN" 4 1491.7305 2.05 112786 7418 2 1491.731882 746.8725 "Nucleoside diphosphate kinase, mitochondrial OS=Homo sapiens OX=9606 GN=NME4 PE=1 SV=1" 5.32 1739.9 - 134442 - - - 0.9003 - 2.249 0.518 - 250.9 1 2 0 0.0013 14 0 0 0 2.56E+09 1.25E+09 - - - 4.9004 0.9983 221125_WJC_METTL3_EV_vs_WT_F08.07423.07423.3 0.0213 Dec-44 K.TIIQNPTDQQK[136.11]K[136.11].D "sp|Q9UQ80|PA2G4_HUMAN,tr|F8VR77|F8VR77_HUMAN" 2 1428.7907 0.21 112788 7423 3 1428.793386 477.2709 Proliferation-associated protein 2G4 OS=Homo sapiens OX=9606 GN=PA2G4 PE=1 SV=3 8.26 1740.5 - 2.40E+06 - - - 1.8498 - 1.596 0.314 - 128.1 1 2 0 0.0026 12 0 0 0 3.89E+07 1.89E+08 - - - 3.3359 0.9913 221125_WJC_METTL3_EV_vs_WT_F08.07425.07425.3 0.000557 Dec-40 R.LHLKEPPPPGR.Q sp|Q12948|FOXC1_HUMAN 1 1239.7088 12.38 112789 7425 3 1239.711601 414.2435 Forkhead box protein C1 OS=Homo sapiens OX=9606 GN=FOXC1 PE=1 SV=3 8.75 1740.7 - 1.25E+06 - - - 2.2667 - 2.622 0.195 - 313.5 1 2 1 0.0028 11 0 0 0 8.19E+08 6.62E+07 - - - 3.4517 0.9647 221125_WJC_METTL3_EV_vs_WT_F08.07428.07428.2 0.00111 26-Nov K.GPGEVAGTVTGQK[136.11]R.R "sp|Q86U44|MTA70_HUMAN,tr|F5H6D8|F5H6D8_HUMAN,tr|H0YFV6|H0YFV6_HUMAN,tr|B4DTN4|B4DTN4_HUMAN" 4 1363.7299 - 112792 7428 2 1364.729156 682.8722 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 8.75 1741.1 - 137364 - - - 732.7177 - 2.346 0.439 - 477.4 1 2 0 0.9992 14 0 0 0 - - - - - 4.1095 0.9927 221125_WJC_METTL3_EV_vs_WT_F08.07436.07436.3 0.172 Sep-36 R.K[136.11]IVDQIR[166.11]PDR[166.11].Q "sp|Q92841|DDX17_HUMAN,sp|P17844|DDX5_HUMAN,tr|A0A7I2V5F5|A0A7I2V5F5_HUMAN,tr|J3KRZ1|J3KRZ1_HUMAN,tr|J3QSF1|J3QSF1_HUMAN,tr|A0A7I2V507|A0A7I2V507_HUMAN,tr|A0A5H1ZRQ2|A0A5H1ZRQ2_HUMAN,tr|J3KTA4|J3KTA4_HUMAN,tr|A0A0G2JLI4|A0A0G2JLI4_HUMAN,tr|A0A1X7SBZ2|A0A1X7SBZ2_HUMAN,tr|A0A7I2V2S0|A0A7I2V2S0_HUMAN" 11 1266.7403 1.42 112796 7436 3 1266.742487 423.254 Probable ATP-dependent RNA helicase DDX17 OS=Homo sapiens OX=9606 GN=DDX17 PE=1 SV=2 8.75 1742.1 - 840452 - - - 1.7588 - 1.65 0.208 - 132.1 1 2 0 0.0022 10 0 0 0 1.13E+09 7.96E+08 - - - 2.3209 0.9999 221125_WJC_METTL3_EV_vs_WT_F08.07441.07441.3 0.00301 Oct-48 R.KYSPGYNTEVGDK.W "sp|O95299|NDUAA_HUMAN,tr|A0A7I2YQU0|A0A7I2YQU0_HUMAN,tr|E7ESZ7|E7ESZ7_HUMAN,tr|A0A7I2V3H5|A0A7I2V3H5_HUMAN,tr|A0A087WXC5|A0A087WXC5_HUMAN,tr|A0A7I2V594|A0A7I2V594_HUMAN" 6 1456.6834 0.49 112799 7441 3 1456.683469 486.5684 "NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 10, mitochondrial OS=Homo sapiens OX=9606 GN=NDUFA10 PE=1 SV=1" 6.07 1742.7 - 433788 - - - 0.0309 - 2.005 0.407 - 86.8 1 2 0 0 13 0 0 0 1.52E+07 3.12E+07 - - - 4.9637 0.9819 221125_WJC_METTL3_EV_vs_WT_F08.07444.07444.2 4.88E-05 22-Dec V.IHASDSVEGAQR.E "sp|O00746|NDKM_HUMAN,tr|Q4TT34|Q4TT34_HUMAN,tr|A0A087WVT9|A0A087WVT9_HUMAN,tr|F2Z2X0|F2Z2X0_HUMAN" 4 1268.6109 2.29 112802 7444 2 1268.609481 635.3127 "Nucleoside diphosphate kinase, mitochondrial OS=Homo sapiens OX=9606 GN=NME4 PE=1 SV=1" 5.32 1743.1 - 237404 - - - -1.1406 - 2.198 0.369 - 517 1 1 0 -0.0014 12 0 0 0 8.01E+07 3.50E+07 - - - 3.8382 0.8738 221125_WJC_METTL3_EV_vs_WT_F08.07448.07448.4 143 Jun-72 R.GEQC[160.03]DC[160.03]GPPEDC[160.03]R[166.11].N sp|P78325|ADAM8_HUMAN 1 1588.558 0.02 112804 7448 4 1588.555636 398.1468 Disintegrin and metalloproteinase domain-containing protein 8 OS=Homo sapiens OX=9606 GN=ADAM8 PE=1 SV=2 3.92 1743.6 - 2.13E+06 - - - -1.4856 - 0.553 0.151 - 9.2 1 2 0 -0.0024 13 0 0 0 3.86E+06 2.21E+08 - - - 0.32 0.993 221125_WJC_METTL3_EV_vs_WT_F08.07450.07450.2 7.56E-05 22-Oct V.IHASDSVEGAQR[166.11].E "sp|O00746|NDKM_HUMAN,tr|Q4TT34|Q4TT34_HUMAN,tr|A0A087WVT9|A0A087WVT9_HUMAN,tr|F2Z2X0|F2Z2X0_HUMAN" 4 1278.6192 2.3 112806 7450 2 1278.619214 640.3169 "Nucleoside diphosphate kinase, mitochondrial OS=Homo sapiens OX=9606 GN=NME4 PE=1 SV=1" 5.32 1743.8 - 451246 - - - 0.0125 - 1.99 0.549 - 368.8 1 1 0 0 12 0 0 0 8.01E+07 3.49E+07 - - - 4.9065 1 221125_WJC_METTL3_EV_vs_WT_F08.07458.07458.2 5.53E-08 13/24 R.AC[160.03]GEGFC[160.03]DSC[160.03]SSK.T "sp|Q9HBF4|ZFYV1_HUMAN,tr|G3V5N8|G3V5N8_HUMAN" 2 1463.5115 1.86 112810 7458 2 1463.50888 732.7631 Zinc finger FYVE domain-containing protein 1 OS=Homo sapiens OX=9606 GN=ZFYVE1 PE=1 SV=1 4.37 1744.7 - 290124 - - - -1.8244 - 2.662 0.77 - 883.6 1 2 0 -0.0027 13 0 0 0 5.25E+06 2.83E+06 - - - 7.2402 0.9999 221125_WJC_METTL3_EV_vs_WT_F08.07463.07463.3 0.000112 17/52 R.SPVSTRPLPSASQK.A sp|Q8ND56|LS14A_HUMAN 1 1453.7889 1.04 112814 7463 3 1453.789211 485.6036 Protein LSM14 homolog A OS=Homo sapiens OX=9606 GN=LSM14A PE=1 SV=3 11 1745.3 - 1.32E+06 - - - 0.2194 - 2.827 0.384 - 340.3 1 2 0 0.0003 14 0 0 0 1.39E+09 1.33E+09 - - - 5.5829 0.9837 221125_WJC_METTL3_EV_vs_WT_F08.07465.07465.2 5.32E-07 15/20 L.HASDSVEGAQR.E "sp|O00746|NDKM_HUMAN,tr|Q4TT34|Q4TT34_HUMAN,tr|A0A087WVT9|A0A087WVT9_HUMAN,tr|F2Z2X0|F2Z2X0_HUMAN" 4 1155.5269 999 112816 7465 2 1155.529756 578.7707 "Nucleoside diphosphate kinase, mitochondrial OS=Homo sapiens OX=9606 GN=NME4 PE=1 SV=1" 5.32 1745.5 - 250114 - - - 2.5028 - 2.461 0.559 - 655.7 1 1 0 0.0029 11 0 0 0 5.54E+06 0.00E+00 - - - 5.6051 0.9986 221125_WJC_METTL3_EV_vs_WT_F08.07471.07471.2 0.0228 18-Aug R.KIVDQIRPDR.Q "sp|Q92841|DDX17_HUMAN,sp|P17844|DDX5_HUMAN,tr|A0A7I2V5F5|A0A7I2V5F5_HUMAN,tr|J3KRZ1|J3KRZ1_HUMAN,tr|J3QSF1|J3QSF1_HUMAN,tr|A0A7I2V507|A0A7I2V507_HUMAN,tr|A0A5H1ZRQ2|A0A5H1ZRQ2_HUMAN,tr|J3KTA4|J3KTA4_HUMAN,tr|A0A0G2JLI4|A0A0G2JLI4_HUMAN,tr|A0A1X7SBZ2|A0A1X7SBZ2_HUMAN,tr|A0A7I2V2S0|A0A7I2V2S0_HUMAN" 11 1238.7095 1.59 112819 7471 2 1238.708641 620.362 Probable ATP-dependent RNA helicase DDX17 OS=Homo sapiens OX=9606 GN=DDX17 PE=1 SV=2 8.75 1746.3 - 736111 - - - -0.7088 - 1.545 0.258 - 132.1 1 2 0 -0.0009 10 0 0 0 8.95E+07 5.61E+07 - - - 2.1606 1 221125_WJC_METTL3_EV_vs_WT_F08.07495.07495.3 6.89E-05 16/48 K.ESEHTGPGWESAR.Q sp|Q8N0X7|SPART_HUMAN 1 1441.6222 1.16 112831 7495 3 1441.619847 481.548 Spartin OS=Homo sapiens OX=9606 GN=SPART PE=1 SV=1 4.75 1749.4 - 1.07E+06 - - - -1.6468 - 2.324 0.511 - 287.6 1 2 0 -0.0024 13 0 0 0 1.39E+08 1.20E+08 - - - 6.5229 1 221125_WJC_METTL3_EV_vs_WT_F08.07502.07502.2 6.89E-05 14/26 R.SPVSTRPLPSASQK.A sp|Q8ND56|LS14A_HUMAN 1 1453.7889 1.05 112836 7502 2 1453.789641 727.9017 Protein LSM14 homolog A OS=Homo sapiens OX=9606 GN=LSM14A PE=1 SV=3 11 1750.2 - 843145 - - - 0.5152 - 3.371 0.556 - 338.7 1 2 0 0.0007 14 0 0 0 7.57E+07 7.21E+07 - - - 6.1969 0.9999 221125_WJC_METTL3_EV_vs_WT_F08.07506.07506.2 0.000641 18/26 R.SPVSTR[166.11]PLPSASQK[136.11].A sp|Q8ND56|LS14A_HUMAN 1 1471.8114 1.05 112838 7506 2 1471.80974 736.913 Protein LSM14 homolog A OS=Homo sapiens OX=9606 GN=LSM14A PE=1 SV=3 11 1750.7 - 982082 - - - -1.102 - 2.827 0.529 - 498.2 1 2 0 -0.0016 14 0 0 0 7.57E+07 7.21E+07 - - - 5.5555 0.9994 221125_WJC_METTL3_EV_vs_WT_F08.07513.07513.2 0.000568 18-Oct R.K[136.11]IVDQIR[166.11]PDR[166.11].Q "sp|Q92841|DDX17_HUMAN,sp|P17844|DDX5_HUMAN,tr|A0A7I2V5F5|A0A7I2V5F5_HUMAN,tr|J3KRZ1|J3KRZ1_HUMAN,tr|J3QSF1|J3QSF1_HUMAN,tr|A0A7I2V507|A0A7I2V507_HUMAN,tr|A0A5H1ZRQ2|A0A5H1ZRQ2_HUMAN,tr|J3KTA4|J3KTA4_HUMAN,tr|A0A0G2JLI4|A0A0G2JLI4_HUMAN,tr|A0A1X7SBZ2|A0A1X7SBZ2_HUMAN,tr|A0A7I2V2S0|A0A7I2V2S0_HUMAN" 11 1266.7403 1.59 112843 7513 2 1266.738487 634.3774 Probable ATP-dependent RNA helicase DDX17 OS=Homo sapiens OX=9606 GN=DDX17 PE=1 SV=2 8.75 1751.6 - 1.81E+06 - - - -1.3989 - 1.484 0.423 - 172.2 1 2 0 -0.0018 10 0 0 0 8.95E+07 5.61E+07 - - - 3.2666 0.9998 221125_WJC_METTL3_EV_vs_WT_F08.07518.07518.3 0.00117 Oct-32 K.K[136.11]DQYFLDK[136.11]K[136.11].M sp|Q9UQE7|SMC3_HUMAN 1 1207.6663 0.73 112846 7518 3 1207.664736 403.5627 Structural maintenance of chromosomes protein 3 OS=Homo sapiens OX=9606 GN=SMC3 PE=1 SV=2 8.43 1752.2 - 1.07E+06 - - - -1.3149 - 1.845 0.404 - 166.7 1 2 0 -0.0016 9 0 0 0 2.32E+07 3.19E+07 - - - 4.8896 0.9799 221125_WJC_METTL3_EV_vs_WT_F08.07519.07519.3 0.0043 Aug-36 R.DSDK[136.11]TDTDWR[166.11].A "sp|P23588|IF4B_HUMAN,tr|E7EX17|E7EX17_HUMAN,tr|F8VSC7|F8VSC7_HUMAN,tr|F8W0K0|F8W0K0_HUMAN,tr|F8VP89|F8VP89_HUMAN" 5 1255.5436 1.97 112847 7519 3 1255.542089 419.5218 Eukaryotic translation initiation factor 4B OS=Homo sapiens OX=9606 GN=EIF4B PE=1 SV=2 4.14 1752.4 - 1.09E+06 - - - -1.1867 - 1.444 0.247 - 101.7 1 2 1 -0.0015 10 0 0 0 6.17E+07 3.13E+07 - - - 2.3664 0.9098 221125_WJC_METTL3_EV_vs_WT_F08.07525.07525.2 7.66 16-Jun K.IVDQIRPDR.Q "sp|Q92841|DDX17_HUMAN,sp|P17844|DDX5_HUMAN,tr|A0A7I2V5F5|A0A7I2V5F5_HUMAN,tr|J3KRZ1|J3KRZ1_HUMAN,tr|J3QSF1|J3QSF1_HUMAN,tr|A0A7I2V507|A0A7I2V507_HUMAN,tr|A0A5H1ZRQ2|A0A5H1ZRQ2_HUMAN,tr|J3KTA4|J3KTA4_HUMAN,tr|A0A0G2JLI4|A0A0G2JLI4_HUMAN,tr|A0A1X7SBZ2|A0A1X7SBZ2_HUMAN,tr|A0A7I2V2S0|A0A7I2V2S0_HUMAN" 11 1110.6146 1.88 112850 7525 2 1110.614911 556.3146 Probable ATP-dependent RNA helicase DDX17 OS=Homo sapiens OX=9606 GN=DDX17 PE=1 SV=2 5.96 1753.2 - 1.12E+06 - - - 0.3196 - 1.112 0.022 - 69.4 5 2 0 0.0004 9 0 0 0 2.29E+07 1.22E+07 - - - -0.8017 0.9722 221125_WJC_METTL3_EV_vs_WT_F08.07530.07530.2 7 16-Jun K.IVDQIR[166.11]PDR[166.11].Q "sp|Q92841|DDX17_HUMAN,sp|P17844|DDX5_HUMAN,tr|A0A7I2V5F5|A0A7I2V5F5_HUMAN,tr|J3KRZ1|J3KRZ1_HUMAN,tr|J3QSF1|J3QSF1_HUMAN,tr|A0A7I2V507|A0A7I2V507_HUMAN,tr|A0A5H1ZRQ2|A0A5H1ZRQ2_HUMAN,tr|J3KTA4|J3KTA4_HUMAN,tr|A0A0G2JLI4|A0A0G2JLI4_HUMAN,tr|A0A1X7SBZ2|A0A1X7SBZ2_HUMAN,tr|A0A7I2V2S0|A0A7I2V2S0_HUMAN" 11 1130.6311 1.88 112854 7530 2 1130.631236 566.3228 Probable ATP-dependent RNA helicase DDX17 OS=Homo sapiens OX=9606 GN=DDX17 PE=1 SV=2 5.96 1753.8 - 485671 - - - 0.1238 - 1.102 0.085 - 69.2 1 2 0 0.0001 9 0 0 0 2.29E+07 1.22E+07 - - - -0.0502 0.9997 221125_WJC_METTL3_EV_vs_WT_F08.07533.07533.3 0.00232 Dec-32 K.KDQYFLDKK.M sp|Q9UQE7|SMC3_HUMAN 1 1183.6237 0.69 112855 7533 3 1183.623195 395.5485 Structural maintenance of chromosomes protein 3 OS=Homo sapiens OX=9606 GN=SMC3 PE=1 SV=2 8.43 1754.2 - 543934 - - - -0.4469 - 1.779 0.351 - 224 1 2 0 -0.0005 9 0 0 0 2.21E+07 3.18E+07 - - - 4.1893 0.9988 221125_WJC_METTL3_EV_vs_WT_F08.07534.07534.2 0.00243 24-Oct K.IFSGSSHQDLSQK[136.11].L "sp|P60891|PRPS1_HUMAN,sp|P21108|PRPS3_HUMAN,tr|A0A2R8Y7H4|A0A2R8Y7H4_HUMAN,tr|Q15244|Q15244_HUMAN,tr|A0A6Q8PHK9|A0A6Q8PHK9_HUMAN,tr|B1ALA9|B1ALA9_HUMAN,tr|A0A6Q8PGF9|A0A6Q8PGF9_HUMAN,tr|B1ALA7|B1ALA7_HUMAN,tr|A0A0B4J207|A0A0B4J207_HUMAN" 9 1440.7089 0.68 112856 7534 2 1440.71332 721.3617 Ribose-phosphate pyrophosphokinase 1 OS=Homo sapiens OX=9606 GN=PRPS1 PE=1 SV=2 6.74 1754.3 - 294481 - - - 3.0978 - 1.722 0.459 - 264.8 1 2 0 0.0045 13 0 0 0 8.35E+06 1.23E+07 - - - 3.8246 1 221125_WJC_METTL3_EV_vs_WT_F08.07535.07535.3 0.000305 13/48 K.IFSGSSHQDLSQK.L "sp|P60891|PRPS1_HUMAN,sp|P21108|PRPS3_HUMAN,tr|A0A2R8Y7H4|A0A2R8Y7H4_HUMAN,tr|Q15244|Q15244_HUMAN,tr|A0A6Q8PHK9|A0A6Q8PHK9_HUMAN,tr|B1ALA9|B1ALA9_HUMAN,tr|A0A6Q8PGF9|A0A6Q8PGF9_HUMAN,tr|B1ALA7|B1ALA7_HUMAN,tr|A0A0B4J207|A0A0B4J207_HUMAN" 9 1432.6947 0.8 112857 7535 3 1432.69549 478.5722 Ribose-phosphate pyrophosphokinase 1 OS=Homo sapiens OX=9606 GN=PRPS1 PE=1 SV=2 6.74 1754.4 - 2.07E+06 - - - 0.5814 - 2.265 0.492 - 178.4 1 2 0 0.0008 13 0 0 0 1.23E+08 1.54E+08 - - - 6.2418 0.9994 221125_WJC_METTL3_EV_vs_WT_F08.07537.07537.3 0.00592 Dec-40 K.VSVHVIEGDHR[166.11].T "sp|P49327|FAS_HUMAN,tr|A0A0U1RQF0|A0A0U1RQF0_HUMAN" 2 1256.6501 0.62 112859 7537 3 1256.650579 419.8906 Fatty acid synthase OS=Homo sapiens OX=9606 GN=FASN PE=1 SV=3 5.99 1754.6 - 897280 - - - 0.378 - 1.758 0.323 - 171.9 1 2 0 0.0005 11 0 0 0 7.32E+07 1.18E+08 - - - 3.7437 0.9964 221125_WJC_METTL3_EV_vs_WT_F08.07539.07539.2 2.85E-06 22-Oct R.SSC[160.03]STPLSQANR[166.11].Y "sp|Q9NRA8|4ET_HUMAN,tr|B1AKL4|B1AKL4_HUMAN" 2 1316.6018 1.27 112861 7539 2 1316.608719 659.3082 Eukaryotic translation initiation factor 4E transporter OS=Homo sapiens OX=9606 GN=EIF4ENIF1 PE=1 SV=2 7.96 1754.8 - 331327 - - - 5.2301 - 1.909 0.501 - 259.6 1 2 0 0.0069 12 0 0 0 1.77E+08 1.39E+08 - - - 4.4405 0.9999 221125_WJC_METTL3_EV_vs_WT_F08.07540.07540.2 8.77E-07 22-Nov R.SSC[160.03]STPLSQANR.Y "sp|Q9NRA8|4ET_HUMAN,tr|B1AKL4|B1AKL4_HUMAN" 2 1306.5936 1.27 112862 7540 2 1306.593157 654.3041 Eukaryotic translation initiation factor 4E transporter OS=Homo sapiens OX=9606 GN=EIF4ENIF1 PE=1 SV=2 7.96 1754.9 - 316633 - - - -0.3107 - 2.101 0.588 - 318.9 1 2 0 -0.0004 12 0 0 0 1.77E+08 1.39E+08 - - - 5.3373 0.9999 221125_WJC_METTL3_EV_vs_WT_F08.07541.07541.2 1.15E-05 18-Sep R.NSDWSSDTNR.Q "sp|P78332|RBM6_HUMAN,tr|C9JII0|C9JII0_HUMAN,tr|F8WCA5|F8WCA5_HUMAN,tr|E9PGM9|E9PGM9_HUMAN" 4 1180.4745 1.2 112863 7541 2 1180.473376 591.2445 RNA-binding protein 6 OS=Homo sapiens OX=9606 GN=RBM6 PE=1 SV=5 4.21 1755.1 - 258958 - - - -0.9471 - 1.959 0.611 - 356.2 1 2 0 -0.0011 10 0 0 0 5.97E+06 4.98E+06 - - - 5.4305 0.9999 221125_WJC_METTL3_EV_vs_WT_F08.07542.07542.2 6.52E-07 18-Oct R.NSDWSSDTNR[166.11].Q "sp|P78332|RBM6_HUMAN,tr|C9JII0|C9JII0_HUMAN,tr|F8WCA5|F8WCA5_HUMAN,tr|E9PGM9|E9PGM9_HUMAN" 4 1190.4828 1.2 112864 7542 2 1190.480985 596.2487 RNA-binding protein 6 OS=Homo sapiens OX=9606 GN=RBM6 PE=1 SV=5 4.21 1755.2 - 248519 - - - -1.4944 - 1.896 0.632 - 510.6 1 2 0 -0.0018 10 0 0 0 5.97E+06 4.98E+06 - - - 5.4941 0.9498 221125_WJC_METTL3_EV_vs_WT_F08.07543.07543.2 0.00401 22-Dec P.VSTR[166.11]PLPSASQK[136.11].A sp|Q8ND56|LS14A_HUMAN 1 1287.7266 0.78 112865 7543 2 1287.728915 644.8706 Protein LSM14 homolog A OS=Homo sapiens OX=9606 GN=LSM14A PE=1 SV=3 11 1755.3 - 224449 - - - 1.821 - 2.11 0.296 - 336.2 1 1 0 0.0023 12 0 0 0 6.67E+06 8.56E+06 - - - 3.1912 0.9999 221125_WJC_METTL3_EV_vs_WT_F08.07544.07544.2 5.25E-07 26-Nov R.GISSSNEGVEEPSK.K sp|Q9NXV6|CARF_HUMAN 1 1418.6525 0.95 112866 7544 2 1418.653201 710.3335 CDKN2A-interacting protein OS=Homo sapiens OX=9606 GN=CDKN2AIP PE=1 SV=3 4.25 1755.5 - 204193 - - - 0.4814 - 2.274 0.523 - 302.1 1 2 0 0.0007 14 0 0 0 7.52E+06 7.92E+06 - - - 4.9653 0.9992 221125_WJC_METTL3_EV_vs_WT_F08.07545.07545.2 0.0142 26-May K.TIIGQQGDQSC[160.03]ANK[136.11].L sp|P35251|RFC1_HUMAN 1 1526.7239 1.23 112867 7545 2 1526.725392 764.3692 Replication factor C subunit 1 OS=Homo sapiens OX=9606 GN=RFC1 PE=1 SV=4 5.5 1755.6 - 158099 - - - 1.0061 - 1.164 0.462 - 51.1 1 2 0 0.0015 14 0 0 0 5.13E+06 4.17E+06 - - - 2.8339 0.9998 221125_WJC_METTL3_EV_vs_WT_F08.07548.07548.3 0.000318 13/48 K.IFSGSSHQDLSQK[136.11].L "sp|P60891|PRPS1_HUMAN,sp|P21108|PRPS3_HUMAN,tr|A0A2R8Y7H4|A0A2R8Y7H4_HUMAN,tr|Q15244|Q15244_HUMAN,tr|A0A6Q8PHK9|A0A6Q8PHK9_HUMAN,tr|B1ALA9|B1ALA9_HUMAN,tr|A0A6Q8PGF9|A0A6Q8PGF9_HUMAN,tr|B1ALA7|B1ALA7_HUMAN,tr|A0A0B4J207|A0A0B4J207_HUMAN" 9 1440.7089 0.77 112868 7548 3 1440.711435 481.2436 Ribose-phosphate pyrophosphokinase 1 OS=Homo sapiens OX=9606 GN=PRPS1 PE=1 SV=2 6.74 1756 - 7.03E+06 - - - 1.7894 - 2.166 0.41 - 184.9 1 2 0 0.0026 13 0 0 0 1.17E+08 1.51E+08 - - - 5.2059 0.9994 221125_WJC_METTL3_EV_vs_WT_F08.07551.07551.3 0.000686 15/48 K.IQDK[136.11]EGIPPDQQR[166.11].L "sp|P62979|RS27A_HUMAN,sp|P0CG48|UBC_HUMAN,sp|P0CG48|UBC_HUMAN,sp|P0CG48|UBC_HUMAN,sp|P0CG48|UBC_HUMAN,sp|P0CG48|UBC_HUMAN,sp|P0CG48|UBC_HUMAN,sp|P0CG48|UBC_HUMAN,sp|P0CG48|UBC_HUMAN,sp|P0CG48|UBC_HUMAN,sp|P0CG47|UBB_HUMAN,sp|P0CG47|UBB_HUMAN,sp|P0CG47|UBB_HUMAN,sp|P62987|RL40_HUMAN,tr|F5H388|F5H388_HUMAN,tr|F5H388|F5H388_HUMAN,tr|F5GYU3|F5GYU3_HUMAN,tr|F5GYU3|F5GYU3_HUMAN,tr|B4DV12|B4DV12_HUMAN,tr|B4DV12|B4DV12_HUMAN,tr|J3QSA3|J3QSA3_HUMAN,tr|Q5PY61|Q5PY61_HUMAN,tr|Q5PY61|Q5PY61_HUMAN,tr|Q5PY61|Q5PY61_HUMAN,tr|F5H2Z3|F5H2Z3_HUMAN,tr|F5H2Z3|F5H2Z3_HUMAN,tr|M0R2S1|M0R2S1_HUMAN,tr|J3QS39|J3QS39_HUMAN,tr|J3QTR3|J3QTR3_HUMAN,tr|Q96C32|Q96C32_HUMAN,tr|Q96C32|Q96C32_HUMAN,tr|Q96C32|Q96C32_HUMAN,tr|Q96C32|Q96C32_HUMAN,tr|M0R1V7|M0R1V7_HUMAN,tr|F5H747|F5H747_HUMAN,tr|F5H747|F5H747_HUMAN,tr|F5GXK7|F5GXK7_HUMAN,tr|F5GXK7|F5GXK7_HUMAN,tr|M0R1M6|M0R1M6_HUMAN,tr|F5H6Q2|F5H6Q2_HUMAN,tr|F5H6Q2|F5H6Q2_HUMAN,tr|F5GZ39|F5GZ39_HUMAN,tr|J3QKN0|J3QKN0_HUMAN,tr|J3QKN0|J3QKN0_HUMAN,tr|F5H265|F5H265_HUMAN,tr|F5H265|F5H265_HUMAN,tr|A0A2R8Y422|A0A2R8Y422_HUMAN" 47 1540.7964 0.66 112871 7551 3 1540.793894 514.6061 Ubiquitin-40S ribosomal protein S27a OS=Homo sapiens OX=9606 GN=RPS27A PE=1 SV=2 4.56 1756.2 - 1.50E+06 - - - -1.6524 - 2.459 0.393 - 355.4 1 2 1 -0.0025 13 0 0 0 7.55E+07 1.15E+08 - - - 5.3604 0.9997 221125_WJC_METTL3_EV_vs_WT_F08.07552.07552.2 9.66E-07 28-Sep K.GC[160.03]PVNTEPSGPTC[160.03]EK.K sp|P53701|CCHL_HUMAN 1 1631.692 1.38 112872 7552 2 1631.69512 816.8533 Holocytochrome c-type synthase OS=Homo sapiens OX=9606 GN=HCCS PE=1 SV=1 4.53 1756.3 - 172729 - - - 1.9385 - 1.997 0.554 - 138.7 1 2 0 0.0032 15 0 0 0 8.58E+06 6.24E+06 - - - 4.8323 0.9264 221125_WJC_METTL3_EV_vs_WT_F08.07556.07556.3 0.000346 14/36 V.SVHVIEGDHR[166.11].T "sp|P49327|FAS_HUMAN,tr|A0A0U1RQF0|A0A0U1RQF0_HUMAN,tr|A0A0C4DFU4|A0A0C4DFU4_HUMAN" 3 1157.5817 0.56 112874 7556 3 1157.576388 386.8678 Fatty acid synthase OS=Homo sapiens OX=9606 GN=FASN PE=1 SV=3 5.94 1756.8 - 659119 - - - -4.5802 - 2.21 0.43 - 299 1 1 0 -0.0053 10 0 0 0 1.54E+07 2.77E+07 - - - 5.6485 0.9999 221125_WJC_METTL3_EV_vs_WT_F08.07559.07559.2 2.30E-07 28-Jun K.GC[160.03]PVNTEPSGPTC[160.03]EK[136.11].K sp|P53701|CCHL_HUMAN 1 1639.7062 1.38 112877 7559 2 1639.704354 820.8604 Holocytochrome c-type synthase OS=Homo sapiens OX=9606 GN=HCCS PE=1 SV=1 4.53 1757.2 - 230515 - - - -1.0996 - 1.522 0.666 - 71.3 1 2 0 -0.0018 15 0 0 0 8.58E+06 6.24E+06 - - - 4.9922 1 221125_WJC_METTL3_EV_vs_WT_F08.07562.07562.3 2.53E-10 15/52 K.K[136.11]GPGEVAGTVTGQK[136.11].R "sp|Q86U44|MTA70_HUMAN,tr|F5H6D8|F5H6D8_HUMAN,tr|H0YFV6|H0YFV6_HUMAN,tr|B4DTN4|B4DTN4_HUMAN" 4 1343.738 0.46 112878 7562 3 1343.737989 448.9199 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 8.59 1757.6 - 3.32E+06 - - - 0.0074 - 3.013 0.569 - 419.8 1 2 0 0 14 0 0 0 3.79E+07 8.17E+07 - - - 7.8149 1 221125_WJC_METTL3_EV_vs_WT_F08.07563.07563.2 9.37E-06 13/24 K.STTSVSEEDVSSR[166.11].Y sp|Q96IZ0|PAWR_HUMAN 1 1392.6244 1.04 112879 7563 2 1392.628289 697.3195 PRKC apoptosis WT1 regulator protein OS=Homo sapiens OX=9606 GN=PAWR PE=1 SV=1 4.14 1757.7 - 324815 - - - 2.7911 - 2.529 0.586 - 505.2 1 2 0 0.0039 13 0 0 0 1.82E+07 1.74E+07 - - - 5.7493 0.9997 221125_WJC_METTL3_EV_vs_WT_F08.07568.07568.3 8.06E-05 Oct-40 R.FFHETEAPR[166.11]PK[136.11].D "sp|P56556|NDUA6_HUMAN,tr|R4GN43|R4GN43_HUMAN,tr|A0A2Y9D025|A0A2Y9D025_HUMAN" 3 1375.7004 1.39 112882 7568 3 1375.696472 459.5741 NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 6 OS=Homo sapiens OX=9606 GN=NDUFA6 PE=1 SV=4 6.76 1758.3 - 994935 - - - -2.8226 - 1.893 0.457 - 109.9 1 2 0 -0.0039 11 0 0 0 6.24E+07 4.48E+07 - - - 5.4469 1 221125_WJC_METTL3_EV_vs_WT_F08.07569.07569.2 2.41E-07 14/24 K.IFSGSSHQDLSQK.L "sp|P60891|PRPS1_HUMAN,sp|P21108|PRPS3_HUMAN,tr|A0A2R8Y7H4|A0A2R8Y7H4_HUMAN,tr|Q15244|Q15244_HUMAN,tr|A0A6Q8PHK9|A0A6Q8PHK9_HUMAN,tr|B1ALA9|B1ALA9_HUMAN,tr|A0A6Q8PGF9|A0A6Q8PGF9_HUMAN,tr|B1ALA7|B1ALA7_HUMAN,tr|A0A0B4J207|A0A0B4J207_HUMAN" 9 1432.6947 0.68 112883 7569 2 1432.69662 717.3546 Ribose-phosphate pyrophosphokinase 1 OS=Homo sapiens OX=9606 GN=PRPS1 PE=1 SV=2 6.74 1758.4 - 439214 - - - 1.3701 - 2.653 0.582 - 486 1 2 0 0.002 13 0 0 0 8.35E+06 1.23E+07 - - - 5.8432 1 221125_WJC_METTL3_EV_vs_WT_F08.07573.07573.2 9.82E-05 20/26 K.K[136.11]GPGEVAGTVTGQK[136.11].R "sp|Q86U44|MTA70_HUMAN,tr|F5H6D8|F5H6D8_HUMAN,tr|H0YFV6|H0YFV6_HUMAN,tr|B4DTN4|B4DTN4_HUMAN" 4 1343.738 0.001 112886 7573 2 1343.739003 672.8763 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 8.59 1758.9 - 1.15E+06 - - - 0.7621 - 3.703 0.566 - 1111 1 2 0 0.001 14 0 0 0 0.00E+00 2.85E+07 - - - 6.5064 0.998 221125_WJC_METTL3_EV_vs_WT_F08.07578.07578.3 0.0124 Aug-36 K.HQDGLWHAAR[166.11].L "sp|Q8N5A5|ZGPAT_HUMAN,tr|A0A0J9YYD9|A0A0J9YYD9_HUMAN,tr|V9GY48|V9GY48_HUMAN" 3 1199.5824 1.8 112890 7578 3 1199.584805 400.8681 Zinc finger CCCH-type with G patch domain-containing protein OS=Homo sapiens OX=9606 GN=ZGPAT PE=1 SV=3 6.92 1759.5 - 447281 - - - 2.0399 - 1.614 0.301 - 82.3 1 2 0 0.0024 10 0 0 0 1.01E+07 5.58E+06 - - - 3.2932 1 221125_WJC_METTL3_EV_vs_WT_F08.07588.07588.3 5.64E-05 14/40 R.FFHETEAPRPK.D "sp|P56556|NDUA6_HUMAN,tr|R4GN43|R4GN43_HUMAN,tr|A0A2Y9D025|A0A2Y9D025_HUMAN" 3 1357.6779 1.09 112896 7588 3 1357.679499 453.5666 NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 6 OS=Homo sapiens OX=9606 GN=NDUFA6 PE=1 SV=4 6.76 1760.7 - 2.50E+06 - - - 1.1888 - 2.351 0.502 - 228.6 1 2 0 0.0016 11 0 0 0 6.58E+07 6.06E+07 - - - 6.5648 0.9989 221125_WJC_METTL3_EV_vs_WT_F08.07602.07602.3 0.0097 Oct-44 K.NQK[136.11]PVPAVPVQK[136.11].S "sp|Q9BW19|KIFC1_HUMAN,tr|A2AB20|A2AB20_HUMAN,tr|A0A140T9E6|A0A140T9E6_HUMAN" 3 1319.7896 0.8 112905 7602 3 1319.791259 440.9372 Kinesin-like protein KIFC1 OS=Homo sapiens OX=9606 GN=KIFC1 PE=1 SV=2 10 1762.4 - 292853 - - - 1.2411 - 1.817 0.286 - 76.7 1 2 0 0.0016 12 0 0 0 1.15E+07 1.44E+07 - - - 3.3835 0.9915 221125_WJC_METTL3_EV_vs_WT_F08.07603.07603.2 5.32E-07 28-Jul L.QTTQSVEGATGSAVK.S "sp|Q14157|UBP2L_HUMAN,tr|F8W726|F8W726_HUMAN" 2 1462.7264 3 112906 7603 2 1462.726976 732.3705 Ubiquitin-associated protein 2-like OS=Homo sapiens OX=9606 GN=UBAP2L PE=1 SV=2 6 1762.6 - 248323 - - - 0.4273 - 2.111 0.515 - 132.7 1 1 0 0.0006 15 0 0 0 5.81E+06 1.93E+06 - - - 4.6815 0.9994 221125_WJC_METTL3_EV_vs_WT_F08.07608.07608.3 0.021 Oct-40 R.FFHETEAPRPK.D "sp|P56556|NDUA6_HUMAN,tr|R4GN43|R4GN43_HUMAN,tr|A0A2Y9D025|A0A2Y9D025_HUMAN" 3 1357.6779 1.09 112909 7608 3 1357.680601 453.5666 NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 6 OS=Homo sapiens OX=9606 GN=NDUFA6 PE=1 SV=4 6.76 1763.3 - 2.92E+06 - - - 2.0005 - 1.814 0.361 - 93.5 1 2 0 0.0027 11 0 0 0 6.58E+07 6.05E+07 - - - 4.2559 0.9956 221125_WJC_METTL3_EV_vs_WT_F08.07611.07611.4 0.00806 13/84 K.LTGR[166.11]DPNDVR[166.11]PIQAR[166.11].L "sp|Q9H307|PININ_HUMAN,tr|G3V5F0|G3V5F0_HUMAN,tr|G3V579|G3V579_HUMAN" 3 1736.9424 1.75 112912 7611 4 1736.945635 435.2429 Pinin OS=Homo sapiens OX=9606 GN=PNN PE=1 SV=5 9.51 1763.5 - 500385 - - - 1.8481 - 1.932 0.31 - 101.5 1 2 1 0.0032 15 0 0 0 6.82E+07 3.90E+07 - - - 2.159 0.9488 221125_WJC_METTL3_EV_vs_WT_F08.07617.07617.3 2.18E-05 Oct-44 G.K[136.11]VEIIANDQGNR[166.11].T "sp|P54652|HSP72_HUMAN,sp|P0DMV8|HS71A_HUMAN,sp|P34931|HS71L_HUMAN,sp|P11142|HSP7C_HUMAN,sp|P0DMV9|HS71B_HUMAN,tr|E9PQQ4|E9PQQ4_HUMAN,tr|E9PNE6|E9PNE6_HUMAN,tr|E9PKE3|E9PKE3_HUMAN,tr|E9PLF4|E9PLF4_HUMAN,tr|Q53FA3|Q53FA3_HUMAN,tr|E9PI65|E9PI65_HUMAN,tr|E9PK54|E9PK54_HUMAN,tr|E9PN25|E9PN25_HUMAN,tr|E9PPY6|E9PPY6_HUMAN,tr|E9PQK7|E9PQK7_HUMAN,tr|A0A0G2JIW1|A0A0G2JIW1_HUMAN" 16 1373.7382 0.28 112917 7617 3 1373.741564 458.92 Heat shock-related 70 kDa protein 2 OS=Homo sapiens OX=9606 GN=HSPA2 PE=1 SV=1 6.07 1764.3 - 1.72E+06 - - - 2.451 - 2.113 0.356 - 223.2 1 1 0 0.0034 12 0 0 0 1.15E+07 4.12E+07 - - - 4.5818 0.9824 221125_WJC_METTL3_EV_vs_WT_F08.07623.07623.2 0.000364 22-Sep G.K[136.11]VEIIANDQGNR[166.11].T "sp|P54652|HSP72_HUMAN,sp|P0DMV8|HS71A_HUMAN,sp|P34931|HS71L_HUMAN,sp|P11142|HSP7C_HUMAN,sp|P0DMV9|HS71B_HUMAN,tr|E9PQQ4|E9PQQ4_HUMAN,tr|E9PNE6|E9PNE6_HUMAN,tr|E9PKE3|E9PKE3_HUMAN,tr|E9PLF4|E9PLF4_HUMAN,tr|Q53FA3|Q53FA3_HUMAN,tr|E9PI65|E9PI65_HUMAN,tr|E9PK54|E9PK54_HUMAN,tr|E9PN25|E9PN25_HUMAN,tr|E9PPY6|E9PPY6_HUMAN,tr|E9PQK7|E9PQK7_HUMAN,tr|A0A0G2JIW1|A0A0G2JIW1_HUMAN" 16 1373.7382 0.01 112922 7623 2 1373.73775 687.8764 Heat shock-related 70 kDa protein 2 OS=Homo sapiens OX=9606 GN=HSPA2 PE=1 SV=1 6.07 1765 - 194179 - - - -0.3254 - 1.616 0.444 - 184.8 1 1 0 -0.0004 12 0 0 0 7.02E+04 6.57E+06 - - - 3.5831 0.9931 221125_WJC_METTL3_EV_vs_WT_F08.07624.07624.2 0.0862 16-Jun K.KDWDDDQND.- "sp|P50990|TCPQ_HUMAN,tr|H7C2U0|H7C2U0_HUMAN" 2 1149.4211 0.31 112923 7624 2 1149.426354 575.7178 T-complex protein 1 subunit theta OS=Homo sapiens OX=9606 GN=CCT8 PE=1 SV=4 3.82 1765.2 - 103976 - - - 4.6049 - 1.024 0.539 - 81.2 1 2 0 0.0053 9 0 0 0 1.25E+07 4.05E+07 - - - 3.089 0.9998 221125_WJC_METTL3_EV_vs_WT_F08.07628.07628.3 6.31E-07 18/56 R.HVAAGTQQPYTDGVR.M sp|P14923|PLAK_HUMAN 1 1598.7801 39.77 112925 7628 3 1598.784816 533.934 Junction plakoglobin OS=Homo sapiens OX=9606 GN=JUP PE=1 SV=3 6.74 1765.7 - 2.85E+06 - - - 2.9385 - 3.093 0.413 - 483.7 1 2 0 0.0047 15 0 0 0 3.67E+08 9.22E+06 - - - 6.0896 0.9997 221125_WJC_METTL3_EV_vs_WT_F08.07632.07632.3 1.29E-07 16/56 K.LTGRDPNDVRPIQAR.L "sp|Q9H307|PININ_HUMAN,tr|G3V5F0|G3V5F0_HUMAN,tr|G3V579|G3V579_HUMAN" 3 1706.9176 1.91 112929 7632 3 1706.921709 569.9798 Pinin OS=Homo sapiens OX=9606 GN=PNN PE=1 SV=5 9.51 1766 - 1.03E+06 - - - 2.3985 - 2.487 0.514 - 193.5 1 2 1 0.0041 15 0 0 0 3.34E+07 1.74E+07 - - - 6.6468 0.9954 221125_WJC_METTL3_EV_vs_WT_F08.07633.07633.3 0.00897 13/44 R.EK[136.11]VDSQYPPVQR[166.11].L sp|P49790|NU153_HUMAN 1 1462.7535 1.5 112930 7633 3 1462.758647 488.5918 Nuclear pore complex protein Nup153 OS=Homo sapiens OX=9606 GN=NUP153 PE=1 SV=2 6.17 1766.1 - 548775 - - - 3.5098 - 2.178 0.355 - 185.3 1 2 1 0.0051 12 0 0 0 1.27E+08 8.51E+07 - - - 4.6541 0.9999 221125_WJC_METTL3_EV_vs_WT_F08.07635.07635.2 4.01E-06 26-Nov R.SGDETPGSEVPGDK.A "sp|Q1KMD3|HNRL2_HUMAN,tr|H3BQZ7|H3BQZ7_HUMAN" 2 1373.5947 1.18 112932 7635 2 1373.594656 687.8046 Heterogeneous nuclear ribonucleoprotein U-like protein 2 OS=Homo sapiens OX=9606 GN=HNRNPUL2 PE=1 SV=1 3.92 1766.3 - 296727 - - - -0.0087 - 1.82 0.618 - 295.6 1 2 0 0 14 0 0 0 2.22E+07 1.88E+07 - - - 5.1083 0.9999 221125_WJC_METTL3_EV_vs_WT_F08.07638.07638.3 2.81E-05 Nov-40 K.VSVHVIEGDHR.T "sp|P49327|FAS_HUMAN,tr|A0A0U1RQF0|A0A0U1RQF0_HUMAN" 2 1246.6418 0.58 112934 7638 3 1246.644775 416.5546 Fatty acid synthase OS=Homo sapiens OX=9606 GN=FASN PE=1 SV=3 5.99 1766.7 - 695511 - - - 2.3591 - 2.367 0.489 - 180.2 1 2 0 0.0029 11 0 0 0 6.82E+07 1.18E+08 - - - 6.4388 0.9993 221125_WJC_METTL3_EV_vs_WT_F08.07639.07639.3 0.00277 Oct-36 K.HLYQIEKPC[160.03]K.E sp|O00443|P3C2A_HUMAN 1 1314.6754 0.27 112935 7639 3 1314.679782 439.2324 Phosphatidylinositol 4-phosphate 3-kinase C2 domain-containing subunit alpha OS=Homo sapiens OX=9606 GN=PIK3C2A PE=1 SV=2 8.18 1766.8 - 1.04E+06 - - - 3.3012 - 1.648 0.43 - 194.8 1 2 0 0.0043 10 0 0 0 3.10E+07 1.17E+08 - - - 4.7918 0.9986 221125_WJC_METTL3_EV_vs_WT_F08.07640.07640.4 0.000172 13/84 K.LTGRDPNDVRPIQAR.L "sp|Q9H307|PININ_HUMAN,tr|G3V5F0|G3V5F0_HUMAN,tr|G3V579|G3V579_HUMAN" 3 1706.9176 1.75 112936 7640 4 1706.922881 427.7367 Pinin OS=Homo sapiens OX=9606 GN=PNN PE=1 SV=5 9.51 1766.8 - 2.83E+06 - - - 3.0851 - 2.004 0.422 - 85.7 1 2 1 0.0053 15 0 0 0 6.85E+07 3.91E+07 - - - 3.1464 0.9644 221125_WJC_METTL3_EV_vs_WT_F08.07641.07641.3 0.129 Nov-44 R.EKVDSQYPPVQR.L sp|P49790|NU153_HUMAN 1 1444.731 1.46 112937 7641 3 1444.735684 482.5843 Nuclear pore complex protein Nup153 OS=Homo sapiens OX=9606 GN=NUP153 PE=1 SV=2 6.17 1766.9 - 862879 - - - 3.2124 - 1.818 0.243 - 158 1 2 1 0.0046 12 0 0 0 1.25E+08 8.54E+07 - - - 2.9048 0.9996 221125_WJC_METTL3_EV_vs_WT_F08.07642.07642.2 0.138 15/28 R.HVAAGTQQPYTDGVR.M sp|P14923|PLAK_HUMAN 1 1598.7801 999 112938 7642 2 1598.784864 800.3973 Junction plakoglobin OS=Homo sapiens OX=9606 GN=JUP PE=1 SV=3 6.74 1767 - 270598 - - - 2.9685 - 3.206 0.507 - 445.6 1 2 0 0.0047 15 0 0 0 2.45E+07 0.00E+00 - - - 5.6485 0.85 221125_WJC_METTL3_EV_vs_WT_F08.07643.07643.2 0.00525 28-Jul L.QTTQSVEGATGSAVK[136.11].S "sp|Q14157|UBP2L_HUMAN,tr|F8W726|F8W726_HUMAN" 2 1470.7406 3 112939 7643 2 1470.744187 736.3776 Ubiquitin-associated protein 2-like OS=Homo sapiens OX=9606 GN=UBAP2L PE=1 SV=2 6 1767.2 - 142691 - - - 2.4722 - 1.457 0.335 - 136.9 1 1 0 0.0036 15 0 0 0 5.81E+06 1.93E+06 - - - 2.4395 0.9999 221125_WJC_METTL3_EV_vs_WT_F08.07646.07646.3 1.79E-08 16/56 K.LTGR[166.11]DPNDVR[166.11]PIQAR[166.11].L "sp|Q9H307|PININ_HUMAN,tr|G3V5F0|G3V5F0_HUMAN,tr|G3V579|G3V579_HUMAN" 3 1736.9424 1.91 112940 7646 3 1736.945467 579.9881 Pinin OS=Homo sapiens OX=9606 GN=PNN PE=1 SV=5 9.51 1767.6 - 1.06E+06 - - - 1.7514 - 2.508 0.569 - 182.3 1 2 1 0.003 15 0 0 0 3.34E+07 1.74E+07 - - - 7.2822 0.9074 221125_WJC_METTL3_EV_vs_WT_F08.07647.07647.3 0.000342 Nov-52 L.TGR[166.11]DPNDVR[166.11]PIQAR[166.11].L "sp|Q9H307|PININ_HUMAN,tr|G3V5F0|G3V5F0_HUMAN,tr|G3V579|G3V579_HUMAN" 3 1623.8584 2.24 112941 7647 3 1623.861378 542.2934 Pinin OS=Homo sapiens OX=9606 GN=PNN PE=1 SV=5 9.17 1767.7 - 232364 - - - 1.8579 - 2.138 0.401 - 113.8 1 1 1 0.003 14 0 0 0 5.04E+06 2.25E+06 - - - 5.0293 0.9759 221125_WJC_METTL3_EV_vs_WT_F08.07651.07651.3 0.122 Dec-48 K.IQDKEGIPPDQQR.L "sp|P62979|RS27A_HUMAN,sp|P0CG48|UBC_HUMAN,sp|P0CG48|UBC_HUMAN,sp|P0CG48|UBC_HUMAN,sp|P0CG48|UBC_HUMAN,sp|P0CG48|UBC_HUMAN,sp|P0CG48|UBC_HUMAN,sp|P0CG48|UBC_HUMAN,sp|P0CG48|UBC_HUMAN,sp|P0CG48|UBC_HUMAN,sp|P0CG47|UBB_HUMAN,sp|P0CG47|UBB_HUMAN,sp|P0CG47|UBB_HUMAN,sp|P62987|RL40_HUMAN,tr|F5H388|F5H388_HUMAN,tr|F5H388|F5H388_HUMAN,tr|F5GYU3|F5GYU3_HUMAN,tr|F5GYU3|F5GYU3_HUMAN,tr|B4DV12|B4DV12_HUMAN,tr|B4DV12|B4DV12_HUMAN,tr|J3QSA3|J3QSA3_HUMAN,tr|Q5PY61|Q5PY61_HUMAN,tr|Q5PY61|Q5PY61_HUMAN,tr|Q5PY61|Q5PY61_HUMAN,tr|F5H2Z3|F5H2Z3_HUMAN,tr|F5H2Z3|F5H2Z3_HUMAN,tr|M0R2S1|M0R2S1_HUMAN,tr|J3QS39|J3QS39_HUMAN,tr|J3QTR3|J3QTR3_HUMAN,tr|Q96C32|Q96C32_HUMAN,tr|Q96C32|Q96C32_HUMAN,tr|Q96C32|Q96C32_HUMAN,tr|Q96C32|Q96C32_HUMAN,tr|M0R1V7|M0R1V7_HUMAN,tr|F5H747|F5H747_HUMAN,tr|F5H747|F5H747_HUMAN,tr|F5GXK7|F5GXK7_HUMAN,tr|F5GXK7|F5GXK7_HUMAN,tr|M0R1M6|M0R1M6_HUMAN,tr|F5H6Q2|F5H6Q2_HUMAN,tr|F5H6Q2|F5H6Q2_HUMAN,tr|F5GZ39|F5GZ39_HUMAN,tr|J3QKN0|J3QKN0_HUMAN,tr|J3QKN0|J3QKN0_HUMAN,tr|F5H265|F5H265_HUMAN,tr|F5H265|F5H265_HUMAN,tr|A0A2R8Y422|A0A2R8Y422_HUMAN" 47 1522.774 0.68 112943 7651 3 1522.77915 508.5986 Ubiquitin-40S ribosomal protein S27a OS=Homo sapiens OX=9606 GN=RPS27A PE=1 SV=2 4.56 1768.3 - 1.19E+06 - - - 3.4017 - 2.064 0.249 - 214.7 1 2 1 0.0052 13 0 0 0 2.16E+07 3.20E+07 - - - 3.2794 0.9996 221125_WJC_METTL3_EV_vs_WT_F08.07654.07654.3 0.000732 14/52 R.SPVSTR[166.11]PLPSASQK[136.11].A sp|Q8ND56|LS14A_HUMAN 1 1471.8114 1.04 112944 7654 3 1471.815182 491.6111 Protein LSM14 homolog A OS=Homo sapiens OX=9606 GN=LSM14A PE=1 SV=3 11 1768.7 - 757085 - - - 2.5954 - 2.336 0.369 - 247.4 1 2 0 0.0038 14 0 0 0 1.39E+09 1.33E+09 - - - 4.9077 0.9999 221125_WJC_METTL3_EV_vs_WT_F08.07657.07657.3 9.40E-05 13/52 R.QSLGHPPPEPGPDR[166.11].V "sp|P13861|KAP2_HUMAN,tr|C9J830|C9J830_HUMAN" 2 1492.7298 2.45 112946 7657 3 1492.73214 498.5839 cAMP-dependent protein kinase type II-alpha regulatory subunit OS=Homo sapiens OX=9606 GN=PRKAR2A PE=1 SV=2 5.32 1769 - 2.25E+06 - - - 1.5602 - 2.595 0.41 - 229.2 1 2 0 0.0023 14 0 0 0 1.49E+08 6.09E+07 - - - 5.6446 0.9963 221125_WJC_METTL3_EV_vs_WT_F08.07664.07664.2 2.46E-05 22-Oct R.EK[136.11]EVEAIQAQAK[136.11].A sp|O15020|SPTN2_HUMAN 1 1358.7376 2.29 112950 7664 2 1358.736529 680.3761 "Spectrin beta chain, non-erythrocytic 2 OS=Homo sapiens OX=9606 GN=SPTBN2 PE=1 SV=3" 4.79 1769.8 - 113948 - - - -0.8214 - 1.952 0.379 - 253.2 1 2 1 -0.0011 12 0 0 0 5.89E+06 2.57E+06 - - - 3.5998 0.9994 221125_WJC_METTL3_EV_vs_WT_F08.07666.07666.3 0.00137 Sep-52 R.QSLGHPPPEPGPDR.V "sp|P13861|KAP2_HUMAN,tr|C9J830|C9J830_HUMAN" 2 1482.7215 1.96 112951 7666 3 1482.725543 495.2478 cAMP-dependent protein kinase type II-alpha regulatory subunit OS=Homo sapiens OX=9606 GN=PRKAR2A PE=1 SV=2 5.32 1770.1 - 6.02E+06 - - - 2.6991 - 2.003 0.383 - 91.3 1 2 0 0.004 14 0 0 0 1.86E+08 9.49E+07 - - - 4.655 0.9999 221125_WJC_METTL3_EV_vs_WT_F08.07669.07669.3 0.0412 13/40 R.ALTHIDHSLSR.Q "sp|P56192|SYMC_HUMAN,tr|F5H2V6|F5H2V6_HUMAN" 2 1248.6575 0.65 112953 7669 3 1248.659886 417.2264 "Methionine--tRNA ligase, cytoplasmic OS=Homo sapiens OX=9606 GN=MARS1 PE=1 SV=2" 6.96 1770.4 - 754961 - - - 1.9237 - 2.651 0.367 - 328.3 1 2 0 0.0024 11 0 0 0 3.37E+07 5.20E+07 - - - 5.4007 0.9898 221125_WJC_METTL3_EV_vs_WT_F08.07671.07671.2 0.0143 22-Jul K.STTTSDPPNIC[160.03]K[136.11].V "sp|Q9Y520|PRC2C_HUMAN,tr|E7EPN9|E7EPN9_HUMAN,tr|H7C5N8|H7C5N8_HUMAN,tr|A0A2R8Y7F4|A0A2R8Y7F4_HUMAN,tr|A0A2R8YET2|A0A2R8YET2_HUMAN" 5 1327.6169 2.14 112955 7671 2 1327.611229 664.8157 Protein PRRC2C OS=Homo sapiens OX=9606 GN=PRRC2C PE=1 SV=4 5.55 1770.7 - 158591 - - - -4.2949 - 1.228 0.392 - 116.7 1 2 0 -0.0057 12 0 0 0 9.12E+07 4.26E+07 - - - 2.4749 0.9983 221125_WJC_METTL3_EV_vs_WT_F08.07677.07677.2 0.0016 16-Jul K.QDSGHLDLR[166.11].N "sp|Q86U44|MTA70_HUMAN,tr|B4E349|B4E349_HUMAN,tr|F5H6D8|F5H6D8_HUMAN,tr|B4DTN4|B4DTN4_HUMAN" 4 1049.5129 0.02 112959 7677 2 1049.515753 525.7637 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 5.21 1771.4 - 1.71E+06 - - - 2.6793 - 1.526 0.383 - 150.8 1 2 0 0.0028 9 0 0 0 8.83E+06 5.83E+08 - - - 3.0917 1 221125_WJC_METTL3_EV_vs_WT_F08.07678.07678.2 1.62E-06 30-Nov R.SASSGAEGDVSSER[166.11]EP.- sp|Q8TEA8|DTD1_HUMAN 1 1573.6731 0.14 112960 7678 2 1573.674285 787.8438 D-aminoacyl-tRNA deacylase 1 OS=Homo sapiens OX=9606 GN=DTD1 PE=1 SV=2 4 1771.5 - 184057 - - - 0.7257 - 2.618 0.637 - 370.3 1 2 1 0.0011 16 0 0 0 1.34E+06 9.52E+06 - - - 6.1117 0.9995 221125_WJC_METTL3_EV_vs_WT_F08.07681.07681.3 0.000819 Dec-44 R.HELQGQK[136.11]PLLEH.- "sp|Q9NRY5|F1142_HUMAN,tr|E7ESJ7|E7ESJ7_HUMAN" 2 1435.7663 1.29 112961 7681 3 1435.769116 479.596 Protein FAM114A2 OS=Homo sapiens OX=9606 GN=FAM114A2 PE=1 SV=4 6 1771.9 - 1.09E+06 - - - 1.9523 - 1.941 0.353 - 185.4 1 2 0 0.0028 12 0 0 0 1.39E+08 1.08E+08 - - - 4.3131 0.9998 221125_WJC_METTL3_EV_vs_WT_F08.07682.07682.2 0.000107 16-Aug K.K[136.11]DWDDDQND.- "sp|P50990|TCPQ_HUMAN,tr|H7C2U0|H7C2U0_HUMAN" 2 1157.4353 0.3 112962 7682 2 1157.436728 579.7249 T-complex protein 1 subunit theta OS=Homo sapiens OX=9606 GN=CCT8 PE=1 SV=4 3.82 1772.1 - 836290 - - - 1.2675 - 1.626 0.548 - 245.9 1 2 0 0.0015 9 0 0 0 1.26E+07 4.15E+07 - - - 4.4944 0.9999 221125_WJC_METTL3_EV_vs_WT_F08.07683.07683.3 2.13E-05 17/56 R.HVAAGTQQPYTDGVR[166.11].M sp|P14923|PLAK_HUMAN 1 1608.7884 39.88 112963 7683 3 1608.793778 537.2701 Junction plakoglobin OS=Homo sapiens OX=9606 GN=JUP PE=1 SV=3 6.74 1772.2 - 523559 - - - 3.3503 - 2.745 0.538 - 431 1 2 0 0.0054 15 0 0 0 3.66E+08 9.17E+06 - - - 7.1716 0.9997 221125_WJC_METTL3_EV_vs_WT_F08.07685.07685.2 3.64E-06 30-Nov R.SGGGGGGGLGSGGSIR.S sp|P35527|K1C9_HUMAN 1 1231.5905 6184.28 112965 7685 2 1231.5938 616.8025 "Keratin, type I cytoskeletal 9 OS=Homo sapiens OX=9606 GN=KRT9 PE=1 SV=3" 9.47 1772.5 - 289627 - - - 2.6584 - 2.634 0.571 - 302.7 1 2 0 0.0033 16 0 0 0 2.17E+08 3.51E+04 - - - 5.6385 0.934 221125_WJC_METTL3_EV_vs_WT_F08.07689.07689.2 0.0732 14-Oct Q.DSGHLDLR[166.11].N "sp|Q86U44|MTA70_HUMAN,tr|B4E349|B4E349_HUMAN,tr|F5H6D8|F5H6D8_HUMAN,tr|B4DTN4|B4DTN4_HUMAN" 4 921.4544 0.02 112967 7689 2 921.456172 461.7345 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 5.21 1773.1 - 1.60E+06 - - - 1.9621 - 2.136 0.224 - 387 1 1 0 0.0018 8 0 0 0 3.65E+06 1.64E+08 - - - 2.9838 0.9995 221125_WJC_METTL3_EV_vs_WT_F08.07690.07690.3 0.000116 Dec-48 K.LKESQTQDNITVR.W sp|Q92900|RENT1_HUMAN 1 1530.8002 1.13 112968 7690 3 1530.805145 511.274 Regulator of nonsense transcripts 1 OS=Homo sapiens OX=9606 GN=UPF1 PE=1 SV=2 6.07 1773.2 - 664982 - - - 3.2401 - 2.492 0.512 - 177.8 1 2 1 0.005 13 0 0 0 1.09E+08 9.65E+07 - - - 6.7226 0.9999 221125_WJC_METTL3_EV_vs_WT_F08.07691.07691.3 0.00705 Dec-44 R.HELQGQKPLLEH.- "sp|Q9NRY5|F1142_HUMAN,tr|E7ESJ7|E7ESJ7_HUMAN" 2 1427.7521 1.29 112969 7691 3 1427.754614 476.9246 Protein FAM114A2 OS=Homo sapiens OX=9606 GN=FAM114A2 PE=1 SV=4 6 1773.2 - 2.10E+06 - - - 1.7517 - 2.248 0.433 - 172.2 1 2 0 0.0025 12 0 0 0 1.40E+08 1.08E+08 - - - 5.6121 0.8926 221125_WJC_METTL3_EV_vs_WT_F08.07696.07696.2 0.593 12-Sep D.SGHLDLR[166.11].N "sp|Q86U44|MTA70_HUMAN,tr|D6R9M9|D6R9M9_HUMAN,tr|B4E349|B4E349_HUMAN,tr|F5H6D8|F5H6D8_HUMAN,tr|B4DTN4|B4DTN4_HUMAN,tr|D6R9X6|D6R9X6_HUMAN" 6 806.4274 0.02 112972 7696 2 806.42899 404.221 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 6.46 1773.7 - 1.84E+06 - - - 1.9456 - 1.672 0.244 - 375.5 1 1 0 0.0016 7 0 0 0 1.99E+06 1.07E+08 - - - 2.4714 0.9681 221125_WJC_METTL3_EV_vs_WT_F08.07698.07698.3 0.0412 Aug-36 R.KHEIEAAIVR.L "sp|Q13618|CUL3_HUMAN,tr|A0A087WTG3|A0A087WTG3_HUMAN" 2 1164.6615 1.91 112974 7698 3 1164.661302 389.2278 Cullin-3 OS=Homo sapiens OX=9606 GN=CUL3 PE=1 SV=2 6.76 1773.9 - 372700 - - - -0.176 - 1.741 0.086 - 98.9 1 2 0 -0.0002 10 0 0 0 1.91E+07 9.97E+06 - - - 1.118 0.9964 221125_WJC_METTL3_EV_vs_WT_F08.07700.07700.3 0.00151 Aug-48 K.ILC[160.03]EQC[160.03]MTSNQKK.A "sp|Q8WXI9|P66B_HUMAN,tr|A0A0U1RRM1|A0A0U1RRM1_HUMAN,tr|A0A0U1RR30|A0A0U1RR30_HUMAN" 3 1638.7528 1.63 112976 7700 3 1638.756735 547.2582 Transcriptional repressor p66-beta OS=Homo sapiens OX=9606 GN=GATAD2B PE=1 SV=1 8.05 1774.2 - 304403 - - - 2.4116 - 1.598 0.292 - 71.3 1 2 0 0.004 13 0 0 0 1.15E+07 7.08E+06 - - - 3.0653 0.9988 221125_WJC_METTL3_EV_vs_WT_F08.07704.07704.3 0.004 Oct-48 K.LK[136.11]ESQTQDNITVR[166.11].W sp|Q92900|RENT1_HUMAN 1 1548.8227 1.13 112978 7704 3 1548.825365 517.2815 Regulator of nonsense transcripts 1 OS=Homo sapiens OX=9606 GN=UPF1 PE=1 SV=2 6.07 1774.7 - 2.65E+06 - - - 1.7497 - 2.025 0.385 - 70.2 1 2 1 0.0027 13 0 0 0 1.09E+08 9.64E+07 - - - 4.7446 0.9997 221125_WJC_METTL3_EV_vs_WT_F08.07705.07705.2 2.81E-05 22-Oct K.STTTSDPPNIC[160.03]K.V "sp|Q9Y520|PRC2C_HUMAN,tr|E7EPN9|E7EPN9_HUMAN,tr|H7C5N8|H7C5N8_HUMAN,tr|A0A2R8Y7F4|A0A2R8Y7F4_HUMAN,tr|A0A2R8YET2|A0A2R8YET2_HUMAN" 5 1319.6027 2.2 112979 7705 2 1319.604292 660.8086 Protein PRRC2C OS=Homo sapiens OX=9606 GN=PRRC2C PE=1 SV=4 5.55 1774.9 - 690343 - - - 1.1829 - 1.998 0.404 - 229.4 1 2 0 0.0016 12 0 0 0 9.97E+07 4.54E+07 - - - 3.8456 0.9986 221125_WJC_METTL3_EV_vs_WT_F08.07708.07708.2 0.00246 24-Jun K.HEQNIDC[160.03]GGGYVK[136.11].L "sp|P27797|CALR_HUMAN,tr|A0A7P0T861|A0A7P0T861_HUMAN,tr|K7EL50|K7EL50_HUMAN" 3 1483.6605 1.83 112982 7708 2 1483.663603 742.8375 Calreticulin OS=Homo sapiens OX=9606 GN=CALR PE=1 SV=1 5.32 1775.2 - 182325 - - - 2.0733 - 1.367 0.412 - 69.6 1 2 0 0.0031 13 0 0 0 5.22E+06 2.85E+06 - - - 2.8854 0.9754 221125_WJC_METTL3_EV_vs_WT_F08.07709.07709.2 0.0328 20-Jun K.QGDEEEK[136.11]WAEK[136.11].A "sp|Q99717|SMAD5_HUMAN,sp|O15198|SMAD9_HUMAN,sp|Q15797|SMAD1_HUMAN,tr|D6RBB4|D6RBB4_HUMAN,tr|A0A7I2R5A4|A0A7I2R5A4_HUMAN,tr|D6RD62|D6RD62_HUMAN,tr|D6REQ3|D6REQ3_HUMAN,tr|D6RAY1|D6RAY1_HUMAN,tr|D6RBH9|D6RBH9_HUMAN,tr|D6R9D4|D6R9D4_HUMAN,tr|D6RIZ9|D6RIZ9_HUMAN,tr|D6RDN7|D6RDN7_HUMAN" 12 1363.6227 1.86 112983 7709 2 1363.624272 682.8186 Mothers against decapentaplegic homolog 5 OS=Homo sapiens OX=9606 GN=SMAD5 PE=1 SV=1 4.25 1775.3 - 162447 - - - 1.1719 - 1.334 0.294 - 140.4 1 2 1 0.0016 11 0 0 0 8.45E+06 4.54E+06 - - - 1.9916 0.9997 221125_WJC_METTL3_EV_vs_WT_F08.07713.07713.2 4.13E-06 24-Jul K.HEQNIDC[160.03]GGGYVK.L "sp|P27797|CALR_HUMAN,tr|A0A7P0T861|A0A7P0T861_HUMAN,tr|K7EL50|K7EL50_HUMAN" 3 1475.6463 1.83 112985 7713 2 1475.649458 738.8304 Calreticulin OS=Homo sapiens OX=9606 GN=CALR PE=1 SV=1 5.32 1775.8 - 176983 - - - 2.1218 - 1.625 0.598 - 124.4 1 2 0 0.0031 13 0 0 0 5.22E+06 2.85E+06 - - - 4.7029 0.9818 221125_WJC_METTL3_EV_vs_WT_F08.07714.07714.2 0.000258 24-Nov K.LKESQTQDNITVR.W sp|Q92900|RENT1_HUMAN 1 1530.8002 1.25 112986 7714 2 1530.80676 766.4074 Regulator of nonsense transcripts 1 OS=Homo sapiens OX=9606 GN=UPF1 PE=1 SV=2 6.07 1776 - 124985 - - - 4.2951 - 2.329 0.461 - 306.2 1 2 1 0.0066 13 0 0 0 6.50E+06 5.18E+06 - - - 4.6137 0.9974 221125_WJC_METTL3_EV_vs_WT_F08.07717.07717.2 0.00029 24-Sep K.LK[136.11]ESQTQDNITVR[166.11].W sp|Q92900|RENT1_HUMAN 1 1548.8227 1.25 112987 7717 2 1548.824767 775.4186 Regulator of nonsense transcripts 1 OS=Homo sapiens OX=9606 GN=UPF1 PE=1 SV=2 6.07 1776.4 - 288967 - - - 1.3636 - 2.179 0.475 - 175.4 1 2 1 0.0021 13 0 0 0 6.50E+06 5.18E+06 - - - 4.5477 0.9999 221125_WJC_METTL3_EV_vs_WT_F08.07718.07718.2 2.27E-06 22-Nov R.QQQQQQQEQLYK[136.11].M sp|Q5JSZ5|PRC2B_HUMAN 1 1583.7783 1.59 112988 7718 2 1583.78008 792.8964 Protein PRRC2B OS=Homo sapiens OX=9606 GN=PRRC2B PE=1 SV=2 6 1776.5 - 204993 - - - 1.1024 - 2.519 0.562 - 516.4 1 2 0 0.0017 12 0 0 0 3.55E+07 2.23E+07 - - - 5.6222 0.9987 221125_WJC_METTL3_EV_vs_WT_F08.07723.07723.3 0.0877 13/36 K.DIKPIIKDEK.G sp|Q14151|SAFB2_HUMAN 1 1197.6969 1.31 112990 7723 3 1197.698485 400.2396 Scaffold attachment factor B2 OS=Homo sapiens OX=9606 GN=SAFB2 PE=1 SV=1 6.12 1777.1 - 2.01E+06 - - - 1.3326 - 2.527 0.29 - 192 1 2 1 0.0016 10 0 0 0 8.58E+07 6.57E+07 - - - 4.4801 0.9995 221125_WJC_METTL3_EV_vs_WT_F08.07724.07724.3 2.00E-06 13/44 R.HGFEAASIK[136.11]EER[166.11].G "sp|P35580|MYH10_HUMAN,tr|E7ERA5|E7ERA5_HUMAN" 2 1390.696 1.6 112991 7724 3 1390.700388 464.5726 Myosin-10 OS=Homo sapiens OX=9606 GN=MYH10 PE=1 SV=3 5.5 1777.2 - 619366 - - - 3.1567 - 2.495 0.51 - 212.7 1 2 1 0.0044 12 0 0 0 2.57E+07 1.61E+07 - - - 6.7591 0.9999 221125_WJC_METTL3_EV_vs_WT_F08.07725.07725.3 3.91E-08 15/44 R.HGFEAASIKEER.G "sp|P35580|MYH10_HUMAN,tr|E7ERA5|E7ERA5_HUMAN" 2 1372.6735 1.64 112992 7725 3 1372.675675 458.5651 Myosin-10 OS=Homo sapiens OX=9606 GN=MYH10 PE=1 SV=3 5.5 1777.3 - 534956 - - - 1.5641 - 3.099 0.546 - 320.2 1 2 1 0.0021 12 0 0 0 2.92E+07 1.79E+07 - - - 7.7619 0.9995 221125_WJC_METTL3_EV_vs_WT_F08.07726.07726.2 2.07E-06 22-Nov R.QQQQQQQEQLYK.M sp|Q5JSZ5|PRC2B_HUMAN 1 1575.7641 1.59 112993 7726 2 1575.769237 788.8893 Protein PRRC2B OS=Homo sapiens OX=9606 GN=PRRC2B PE=1 SV=2 6 1777.4 - 370102 - - - 3.2384 - 2.517 0.527 - 454.2 1 2 0 0.0051 12 0 0 0 3.55E+07 2.23E+07 - - - 5.3606 0.977 221125_WJC_METTL3_EV_vs_WT_F08.07727.07727.2 0.00137 20-Oct K.QGDEEEKWAEK.A "sp|Q99717|SMAD5_HUMAN,sp|O15198|SMAD9_HUMAN,sp|Q15797|SMAD1_HUMAN,tr|D6RBB4|D6RBB4_HUMAN,tr|A0A7I2R5A4|A0A7I2R5A4_HUMAN,tr|D6RD62|D6RD62_HUMAN,tr|D6REQ3|D6REQ3_HUMAN,tr|D6RAY1|D6RAY1_HUMAN,tr|D6RBH9|D6RBH9_HUMAN,tr|D6R9D4|D6R9D4_HUMAN,tr|D6RIZ9|D6RIZ9_HUMAN,tr|D6RDN7|D6RDN7_HUMAN" 12 1347.5943 1.86 112994 7727 2 1347.598979 674.8044 Mothers against decapentaplegic homolog 5 OS=Homo sapiens OX=9606 GN=SMAD5 PE=1 SV=1 4.25 1777.6 - 341562 - - - 3.4914 - 1.688 0.412 - 302.8 1 2 1 0.0047 11 0 0 0 8.45E+06 4.54E+06 - - - 3.4989 0.9999 221125_WJC_METTL3_EV_vs_WT_F08.07730.07730.3 0.000127 Nov-36 R.KQEELVQQVR.K "sp|O95983|MBD3_HUMAN,tr|K7EIE8|K7EIE8_HUMAN" 2 1255.6885 1.25 112995 7730 3 1255.687329 419.5701 Methyl-CpG-binding domain protein 3 OS=Homo sapiens OX=9606 GN=MBD3 PE=1 SV=1 6.14 1778 - 2.14E+06 - - - -0.8927 - 2.395 0.42 - 296.7 1 2 0 -0.0011 10 0 0 0 7.96E+07 6.39E+07 - - - 5.7729 0.9997 221125_WJC_METTL3_EV_vs_WT_F08.07733.07733.2 0.00275 16-Sep K.QDSGHLDLR.N "sp|Q86U44|MTA70_HUMAN,tr|B4E349|B4E349_HUMAN,tr|F5H6D8|F5H6D8_HUMAN,tr|B4DTN4|B4DTN4_HUMAN" 4 1039.5047 0.02 112998 7733 2 1039.504851 520.7596 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 5.21 1778.4 - 536186 - - - 0.1732 - 1.805 0.413 - 267.5 1 2 0 0.0002 9 0 0 0 8.83E+06 5.82E+08 - - - 3.7999 0.9999 221125_WJC_METTL3_EV_vs_WT_F08.07734.07734.2 0.00045 18-Dec R.KQEELVQQVR.K "sp|O95983|MBD3_HUMAN,tr|K7EIE8|K7EIE8_HUMAN" 2 1255.6885 1.27 112999 7734 2 1255.689514 628.8515 Methyl-CpG-binding domain protein 3 OS=Homo sapiens OX=9606 GN=MBD3 PE=1 SV=1 6.14 1778.5 - 421884 - - - 0.8473 - 2.646 0.44 - 692.5 1 2 0 0.0011 10 0 0 0 1.78E+07 1.41E+07 - - - 5.0066 0.9999 221125_WJC_METTL3_EV_vs_WT_F08.07737.07737.3 2.89E-05 16/44 K.DKLVYVHTNGPK.K "sp|Q7L2E3|DHX30_HUMAN,tr|H7BXY3|H7BXY3_HUMAN" 2 1369.7354 1.25 113000 7737 3 1369.736508 457.5857 ATP-dependent RNA helicase DHX30 OS=Homo sapiens OX=9606 GN=DHX30 PE=1 SV=1 8.51 1778.9 - 1.14E+06 - - - 0.8089 - 2.716 0.493 - 367 1 2 1 0.0011 12 0 0 0 4.06E+07 3.25E+07 - - - 6.8057 0.8008 221125_WJC_METTL3_EV_vs_WT_F08.07743.07743.3 14.3 14/56 R.PAGAEKPYIC[160.03]NEC[160.03]GK.S sp|Q9UEG4|ZN629_HUMAN 1 1692.76 0.96 113004 7743 3 1692.755166 565.2606 Zinc finger protein 629 OS=Homo sapiens OX=9606 GN=ZNF629 PE=1 SV=2 6.48 1779.6 - 355201 - - - -2.8421 - 1.976 0.291 - 188.1 1 1 0 -0.0048 15 0 0 0 1.51E+07 1.57E+07 - - - 3.5602 0.9996 221125_WJC_METTL3_EV_vs_WT_F08.07751.07751.2 0.0146 13/18 R.K[136.11]QEELVQQVR[166.11].K "sp|O95983|MBD3_HUMAN,tr|K7EIE8|K7EIE8_HUMAN" 2 1273.7109 1.27 113008 7751 2 1273.711758 637.8627 Methyl-CpG-binding domain protein 3 OS=Homo sapiens OX=9606 GN=MBD3 PE=1 SV=1 6.14 1780.6 - 440257 - - - 0.6579 - 2.345 0.254 - 648.2 1 2 0 0.0008 10 0 0 0 1.78E+07 1.41E+07 - - - 3.2958 0.9336 221125_WJC_METTL3_EV_vs_WT_F08.07755.07755.3 0.00211 Nov-44 K.SYVSEK[136.11]DVTSAK[136.11].A "sp|P42704|LPPRC_HUMAN,tr|A0A804HI14|A0A804HI14_HUMAN,tr|A0A804HL40|A0A804HL40_HUMAN,tr|A0A804HKJ0|A0A804HKJ0_HUMAN,tr|A0A804HKR3|A0A804HKR3_HUMAN,tr|A0A804HIN4|A0A804HIN4_HUMAN,tr|A0A804HLG8|A0A804HLG8_HUMAN,tr|A0A804HHY9|A0A804HHY9_HUMAN,tr|A0A804HJZ1|A0A804HJZ1_HUMAN,tr|A0A804HK30|A0A804HK30_HUMAN,tr|A0A804HKI2|A0A804HKI2_HUMAN,tr|A0A804HIG4|A0A804HIG4_HUMAN" 12 1328.6795 0.79 113010 7755 3 1328.683214 443.9004 "Leucine-rich PPR motif-containing protein, mitochondrial OS=Homo sapiens OX=9606 GN=LRPPRC PE=1 SV=3" 5.79 1781.2 - 1.95E+06 - - - 2.8246 - 1.981 0.167 - 112.4 1 2 1 0.0038 12 0 0 0 3.98E+07 5.06E+07 - - - 2.2957 0.9913 221125_WJC_METTL3_EV_vs_WT_F08.07756.07756.3 0.0266 Dec-44 R.QQQQQQQEQLYK[136.11].M sp|Q5JSZ5|PRC2B_HUMAN 1 1583.7783 50.37 113011 7756 3 1583.781161 528.9334 Protein PRRC2B OS=Homo sapiens OX=9606 GN=PRRC2B PE=1 SV=2 6 1781.3 - 414116 - - - 1.785 - 1.361 0.253 - 188.9 1 2 0 0.0028 12 0 0 0 3.83E+08 7.61E+06 - - - 2.2143 0.9727 221125_WJC_METTL3_EV_vs_WT_F08.07759.07759.2 0.205 26-Apr K.EPQPEQPQPSTSAN.- "sp|Q9GZR7|DDX24_HUMAN,tr|A0A087WXU8|A0A087WXU8_HUMAN,tr|F5GYL3|F5GYL3_HUMAN,tr|G3V529|G3V529_HUMAN" 4 1508.6743 - 113014 7759 2 1508.67827 755.3444 ATP-dependent RNA helicase DDX24 OS=Homo sapiens OX=9606 GN=DDX24 PE=1 SV=1 3.8 1781.7 - 73601.2 - - - 2.6208 - 1.094 0.223 - 43.6 2 2 0 0.004 14 0 0 0 - - - - - 0.7778 1 221125_WJC_METTL3_EV_vs_WT_F08.07765.07765.3 3.17E-08 16/52 R.QLSMSSADSADAKR.T sp|Q5JSZ5|PRC2B_HUMAN 1 1465.6831 1.6 113017 7765 3 1465.685215 489.5683 Protein PRRC2B OS=Homo sapiens OX=9606 GN=PRRC2B PE=1 SV=2 5.96 1782.4 - 1.02E+06 - - - 1.4389 - 2.707 0.555 - 357.8 1 2 0 0.0021 14 0 0 0 7.47E+07 4.67E+07 - - - 7.3736 0.9994 221125_WJC_METTL3_EV_vs_WT_F08.07767.07767.3 5.46E-06 Oct-44 K.GTEITHAVVIK[136.11]K[136.11].L "sp|Q99613|EIF3C_HUMAN,sp|B5ME19|EIFCL_HUMAN" 2 1310.7893 0.94 113019 7767 3 1310.793882 437.937 Eukaryotic translation initiation factor 3 subunit C OS=Homo sapiens OX=9606 GN=EIF3C PE=1 SV=1 8.6 1782.5 - 2.07E+06 - - - 3.5063 - 2.279 0.39 - 115.5 1 2 0 0.0046 12 0 0 0 4.65E+07 4.96E+07 - - - 5.1701 0.81 221125_WJC_METTL3_EV_vs_WT_F08.07772.07772.3 1.66 Aug-36 R.IHFHNLQGEK[136.11].F "sp|Q8TC12|RDH11_HUMAN,tr|G3V234|G3V234_HUMAN,tr|H0YIZ8|H0YIZ8_HUMAN,tr|G3V2G6|G3V2G6_HUMAN,tr|H0YJ46|H0YJ46_HUMAN" 5 1229.6397 0.81 113022 7772 3 1229.643099 410.8872 Retinol dehydrogenase 11 OS=Homo sapiens OX=9606 GN=RDH11 PE=1 SV=2 6.92 1783.2 - 708812 - - - 2.8008 - 1.365 0.112 - 56.3 1 2 0 0.0034 10 0 0 0 1.79E+07 2.22E+07 - - - 0.6964 0.7822 221125_WJC_METTL3_EV_vs_WT_F08.07774.07774.3 0.24 Jul-40 K.SK[136.11]GNYDEGFGR[166.11].K "sp|Q9BT23|LIMD2_HUMAN,tr|J3KRR0|J3KRR0_HUMAN,tr|J3QQM5|J3QQM5_HUMAN,tr|J3QL69|J3QL69_HUMAN" 4 1246.5697 1.12 113024 7774 3 1246.57435 416.5305 LIM domain-containing protein 2 OS=Homo sapiens OX=9606 GN=LIMD2 PE=1 SV=1 5.79 1783.5 - 246944 - - - 3.7022 - 1.428 0.206 - 75.4 1 2 1 0.0046 11 0 0 0 7.46E+06 6.64E+06 - - - 1.8475 0.7978 221125_WJC_METTL3_EV_vs_WT_F08.07775.07775.3 0.126 Nov-44 R.EQVLHHPQLGER[166.11].L sp|Q9P2D1|CHD7_HUMAN 1 1451.7509 2.12 113025 7775 3 1451.757298 484.9242 Chromodomain-helicase-DNA-binding protein 7 OS=Homo sapiens OX=9606 GN=CHD7 PE=1 SV=3 6.01 1783.6 - 236872 - - - 4.4209 - 1.737 0.112 - 173.2 1 2 0 0.0064 12 0 0 0 6.68E+07 3.15E+07 - - - 1.3174 0.9996 221125_WJC_METTL3_EV_vs_WT_F08.07776.07776.2 2.05E-06 18-Aug K.NHEEEMNALR.G "sp|Q04695|K1C17_HUMAN,sp|P02533|K1C14_HUMAN,tr|K7EPJ9|K7EPJ9_HUMAN,tr|K7ESE1|K7ESE1_HUMAN,tr|F5GWP8|F5GWP8_HUMAN" 5 1241.5459 14.46 113026 7776 2 1241.547436 621.7802 "Keratin, type I cytoskeletal 17 OS=Homo sapiens OX=9606 GN=KRT17 PE=1 SV=2" 4.75 1783.7 - 188358 - - - 1.2501 - 1.891 0.389 - 293.3 1 2 0 0.0016 10 0 0 0 2.89E+07 2.00E+06 - - - 3.692 0.8962 221125_WJC_METTL3_EV_vs_WT_F08.07777.07777.2 0.0481 18-Jun T.EITHAVVIK[136.11]K[136.11].L "sp|Q99613|EIF3C_HUMAN,sp|B5ME19|EIFCL_HUMAN" 2 1152.7201 1.1 113027 7777 2 1152.722715 577.3673 Eukaryotic translation initiation factor 3 subunit C OS=Homo sapiens OX=9606 GN=EIF3C PE=1 SV=1 8.69 1783.9 - 72876.8 - - - 2.2304 - 1.403 0.364 - 85.5 1 1 0 0.0026 10 0 0 0 1.02E+06 9.32E+05 - - - 2.6739 0.9965 221125_WJC_METTL3_EV_vs_WT_F08.07780.07780.3 0.0253 Nov-32 R.HEHQVMLMR.Q "sp|Q15233|NONO_HUMAN,tr|A0A7I2V535|A0A7I2V535_HUMAN,tr|A0A7I2V4N2|A0A7I2V4N2_HUMAN,tr|A0A7I2V4K9|A0A7I2V4K9_HUMAN,tr|A0A7I2V464|A0A7I2V464_HUMAN,tr|A0A7P0MRW0|A0A7P0MRW0_HUMAN,tr|H7C367|H7C367_HUMAN,tr|A0A7I2V4J2|A0A7I2V4J2_HUMAN,tr|A0A7I2V5Y7|A0A7I2V5Y7_HUMAN,tr|C9JYS8|C9JYS8_HUMAN" 10 1179.5641 0.64 113028 7780 3 1179.565373 394.1953 Non-POU domain-containing octamer-binding protein OS=Homo sapiens OX=9606 GN=NONO PE=1 SV=4 6.92 1784.3 - 245474 - - - 1.0648 - 1.411 0.266 - 175.8 1 2 0 0.0013 9 0 0 0 8.22E+06 1.27E+07 - - - 2.5429 0.9992 221125_WJC_METTL3_EV_vs_WT_F08.07784.07784.3 0.0398 13/44 K.DK[136.11]LVYVHTNGPK[136.11].K "sp|Q7L2E3|DHX30_HUMAN,tr|H7BXY3|H7BXY3_HUMAN" 2 1385.7638 1.25 113030 7784 3 1385.767368 462.9285 ATP-dependent RNA helicase DHX30 OS=Homo sapiens OX=9606 GN=DHX30 PE=1 SV=1 8.51 1784.7 - 578885 - - - 2.5748 - 2.497 0.414 - 215.5 1 2 1 0.0036 12 0 0 0 4.03E+07 3.23E+07 - - - 5.6912 1 221125_WJC_METTL3_EV_vs_WT_F08.07785.07785.2 0.0109 26-Dec Y.GQESGGFSGPGENR[166.11].S "sp|Q01844|EWS_HUMAN,tr|B0QYK0|B0QYK0_HUMAN" 2 1387.5992 0.65 113031 7785 2 1387.602684 694.8069 RNA-binding protein EWS OS=Homo sapiens OX=9606 GN=EWSR1 PE=1 SV=1 4.53 1784.9 - 199415 - - - 2.518 - 2.673 0.578 - 554.1 1 1 0 0.0035 14 0 0 0 4.00E+07 6.10E+07 - - - 5.7763 0.9995 221125_WJC_METTL3_EV_vs_WT_F08.07786.07786.3 0.000343 Oct-60 K.IQHMQPSPQAC[160.03]NSAMK.N sp|Q9H1E1|RNAS7_HUMAN 1 1826.8226 185.6 113032 7786 3 1826.828484 609.9481 Ribonuclease 7 OS=Homo sapiens OX=9606 GN=RNASE7 PE=1 SV=2 8.23 1785 - 213016 - - - 3.2242 - 1.786 0.449 - 79.5 1 2 0 0.0059 16 0 0 0 1.22E+07 6.59E+04 - - - 5.0324 0.9947 221125_WJC_METTL3_EV_vs_WT_F08.07787.07787.2 1.28E-07 26-Nov Y.GQESGGFSGPGENR.S "sp|Q01844|EWS_HUMAN,tr|B0QYK0|B0QYK0_HUMAN" 2 1377.5909 0.65 113033 7787 2 1377.591004 689.8027 RNA-binding protein EWS OS=Homo sapiens OX=9606 GN=EWSR1 PE=1 SV=1 4.53 1785.1 - 108344 - - - 0.061 - 2.592 0.554 - 416.3 1 1 0 0.0001 14 0 0 0 4.00E+07 6.10E+07 - - - 5.5229 0.9961 221125_WJC_METTL3_EV_vs_WT_F08.07797.07797.3 0.00267 15/48 K.IQDK[136.11]EGIPPDQQR[166.11].L "sp|P62979|RS27A_HUMAN,sp|P0CG48|UBC_HUMAN,sp|P0CG48|UBC_HUMAN,sp|P0CG48|UBC_HUMAN,sp|P0CG48|UBC_HUMAN,sp|P0CG48|UBC_HUMAN,sp|P0CG48|UBC_HUMAN,sp|P0CG48|UBC_HUMAN,sp|P0CG48|UBC_HUMAN,sp|P0CG48|UBC_HUMAN,sp|P0CG47|UBB_HUMAN,sp|P0CG47|UBB_HUMAN,sp|P0CG47|UBB_HUMAN,sp|P62987|RL40_HUMAN,tr|F5H388|F5H388_HUMAN,tr|F5H388|F5H388_HUMAN,tr|F5GYU3|F5GYU3_HUMAN,tr|F5GYU3|F5GYU3_HUMAN,tr|B4DV12|B4DV12_HUMAN,tr|B4DV12|B4DV12_HUMAN,tr|J3QSA3|J3QSA3_HUMAN,tr|Q5PY61|Q5PY61_HUMAN,tr|Q5PY61|Q5PY61_HUMAN,tr|Q5PY61|Q5PY61_HUMAN,tr|F5H2Z3|F5H2Z3_HUMAN,tr|F5H2Z3|F5H2Z3_HUMAN,tr|M0R2S1|M0R2S1_HUMAN,tr|J3QS39|J3QS39_HUMAN,tr|J3QTR3|J3QTR3_HUMAN,tr|Q96C32|Q96C32_HUMAN,tr|Q96C32|Q96C32_HUMAN,tr|Q96C32|Q96C32_HUMAN,tr|Q96C32|Q96C32_HUMAN,tr|M0R1V7|M0R1V7_HUMAN,tr|F5H747|F5H747_HUMAN,tr|F5H747|F5H747_HUMAN,tr|F5GXK7|F5GXK7_HUMAN,tr|F5GXK7|F5GXK7_HUMAN,tr|M0R1M6|M0R1M6_HUMAN,tr|F5H6Q2|F5H6Q2_HUMAN,tr|F5H6Q2|F5H6Q2_HUMAN,tr|F5GZ39|F5GZ39_HUMAN,tr|J3QKN0|J3QKN0_HUMAN,tr|J3QKN0|J3QKN0_HUMAN,tr|F5H265|F5H265_HUMAN,tr|F5H265|F5H265_HUMAN,tr|A0A2R8Y422|A0A2R8Y422_HUMAN" 47 1540.7964 0.68 113037 7797 3 1540.801855 514.6061 Ubiquitin-40S ribosomal protein S27a OS=Homo sapiens OX=9606 GN=RPS27A PE=1 SV=2 4.56 1786.5 - 1.14E+06 - - - 3.5144 - 2.148 0.377 - 365.4 1 2 1 0.0054 13 0 0 0 6.90E+07 1.01E+08 - - - 4.8146 0.9998 221125_WJC_METTL3_EV_vs_WT_F08.07809.07809.3 1.19E-07 17/52 K.K[136.11]GPGEVAGTVTGQK[136.11].R "sp|Q86U44|MTA70_HUMAN,tr|F5H6D8|F5H6D8_HUMAN,tr|H0YFV6|H0YFV6_HUMAN,tr|B4DTN4|B4DTN4_HUMAN" 4 1343.738 0.19 113044 7809 3 1343.74412 448.9199 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 8.59 1788 - 2.69E+06 - - - 4.5701 - 2.924 0.551 - 520.4 1 2 0 0.0061 14 0 0 0 3.60E+07 1.86E+08 - - - 7.5328 0.9999 221125_WJC_METTL3_EV_vs_WT_F08.07810.07810.3 1.14E-07 13/52 K.LTQIQESQVTSHNK[136.11].E sp|Q92541|RTF1_HUMAN 1 1619.8358 0.48 113045 7810 3 1619.841302 540.9526 RNA polymerase-associated protein RTF1 homolog OS=Homo sapiens OX=9606 GN=RTF1 PE=1 SV=4 6.75 1788.1 - 1.48E+06 - - - 3.3664 - 2.831 0.54 - 277.5 1 2 0 0.0055 14 0 0 0 1.53E+07 3.21E+07 - - - 7.3245 0.9996 221125_WJC_METTL3_EV_vs_WT_F08.07811.07811.2 3.00E-06 18-Nov K.STTTGHLIYK[136.11].C "sp|Q05639|EF1A2_HUMAN,sp|P68104|EF1A1_HUMAN,sp|Q5VTE0|EF1A3_HUMAN,tr|A0A2R8Y488|A0A2R8Y488_HUMAN,tr|A0A2R8YDN5|A0A2R8YDN5_HUMAN,tr|A0A7I2V659|A0A7I2V659_HUMAN,tr|A0A7I2V3H3|A0A7I2V3H3_HUMAN,tr|Q5JR01|Q5JR01_HUMAN,tr|A0A2U3TZH3|A0A2U3TZH3_HUMAN,tr|A0A7I2V5N4|A0A7I2V5N4_HUMAN,tr|A0A087WVQ9|A0A087WVQ9_HUMAN,tr|A6PW80|A6PW80_HUMAN,tr|A0A087WV01|A0A087WV01_HUMAN,tr|A0A2R8Y660|A0A2R8Y660_HUMAN,tr|A0A6Q8PFK6|A0A6Q8PFK6_HUMAN" 15 1127.6066 0.68 113046 7811 2 1127.609763 564.8106 Elongation factor 1-alpha 2 OS=Homo sapiens OX=9606 GN=EEF1A2 PE=1 SV=1 8.33 1788.2 - 532315 - - - 2.7838 - 2.297 0.514 - 627.7 1 2 0 0.0031 10 0 0 0 1.03E+07 1.50E+07 - - - 5.1577 0.9958 221125_WJC_METTL3_EV_vs_WT_F08.07812.07812.3 0.000235 Nov-56 K.HPPAPAEPSSDLASK[136.11].L "sp|Q9P2E9|RRBP1_HUMAN,tr|A0A087WU26|A0A087WU26_HUMAN,tr|A0A087WVV2|A0A087WVV2_HUMAN,tr|F8W7S5|F8W7S5_HUMAN" 4 1510.7507 1.44 113047 7812 3 1510.757818 504.5909 Ribosome-binding protein 1 OS=Homo sapiens OX=9606 GN=RRBP1 PE=1 SV=5 5.32 1788.3 - 308938 - - - 4.697 - 2.581 0.285 - 156.7 1 2 0 0.0071 15 0 0 0 1.30E+08 8.99E+07 - - - 4.1896 0.9998 221125_WJC_METTL3_EV_vs_WT_F08.07815.07815.2 1.96E-06 28-Aug R.VNNSTGTSEDPSLQR[166.11].S sp|Q9UHR4|BI2L1_HUMAN 1 1613.7521 0.98 113048 7815 2 1613.754941 807.8833 Brain-specific angiogenesis inhibitor 1-associated protein 2-like protein 1 OS=Homo sapiens OX=9606 GN=BAIAP2L1 PE=1 SV=2 4.37 1788.7 - 182189 - - - 1.784 - 2.159 0.631 - 110.2 1 2 0 0.0029 15 0 0 0 4.44E+06 4.53E+06 - - - 5.5929 1 221125_WJC_METTL3_EV_vs_WT_F08.07816.07816.2 3.38E-08 28-Nov R.VNNSTGTSEDPSLQR.S sp|Q9UHR4|BI2L1_HUMAN 1 1603.7438 0.98 113049 7816 2 1603.742541 802.8792 Brain-specific angiogenesis inhibitor 1-associated protein 2-like protein 1 OS=Homo sapiens OX=9606 GN=BAIAP2L1 PE=1 SV=2 4.37 1788.9 - 98288.2 - - - -0.78 - 2.536 0.675 - 304.4 1 2 0 -0.0013 15 0 0 0 4.44E+06 4.53E+06 - - - 6.3141 1 221125_WJC_METTL3_EV_vs_WT_F08.07817.07817.3 1.02E-06 14/56 K.HPPAPAEPSSDLASK.L "sp|Q9P2E9|RRBP1_HUMAN,tr|A0A087WU26|A0A087WU26_HUMAN,tr|A0A087WVV2|A0A087WVV2_HUMAN,tr|F8W7S5|F8W7S5_HUMAN" 4 1502.7365 1.44 113050 7817 3 1502.734851 501.9195 Ribosome-binding protein 1 OS=Homo sapiens OX=9606 GN=RRBP1 PE=1 SV=5 5.32 1789 - 607188 - - - -1.112 - 2.531 0.488 - 257.1 1 2 0 -0.0017 15 0 0 0 1.30E+08 8.99E+07 - - - 6.4034 1 221125_WJC_METTL3_EV_vs_WT_F08.07821.07821.2 4.36E-06 20/26 K.K[136.11]GPGEVAGTVTGQK[136.11].R "sp|Q86U44|MTA70_HUMAN,tr|F5H6D8|F5H6D8_HUMAN,tr|H0YFV6|H0YFV6_HUMAN,tr|B4DTN4|B4DTN4_HUMAN" 4 1343.738 0.001 113053 7821 2 1343.741733 672.8763 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 8.59 1789.4 - 608932 - - - 2.7937 - 3.584 0.553 - 1124.1 1 2 0 0.0038 14 0 0 0 0.00E+00 5.91E+07 - - - 6.3275 0.9651 221125_WJC_METTL3_EV_vs_WT_F08.07823.07823.3 0.00819 Jun-52 A.EAEEGDADASDAKR.K "sp|O95602|RPA1_HUMAN,tr|B9ZVN9|B9ZVN9_HUMAN" 2 1462.6172 5.24 113054 7823 3 1462.616388 488.5463 DNA-directed RNA polymerase I subunit RPA1 OS=Homo sapiens OX=9606 GN=POLR1A PE=1 SV=2 4.02 1789.6 - 2.42E+06 - - - -0.5518 - 1.189 0.459 - 36.9 1 1 0 -0.0008 14 0 0 0 8.55E+07 1.63E+07 - - - 4.1172 0.9921 221125_WJC_METTL3_EV_vs_WT_F08.07824.07824.3 0.132 May-40 R.NADHSMNYQYR.- "sp|Q12906|ILF3_HUMAN,tr|K7ELV3|K7ELV3_HUMAN" 2 1397.5782 1.29 113055 7824 3 1397.583538 466.8667 Interleukin enhancer-binding factor 3 OS=Homo sapiens OX=9606 GN=ILF3 PE=1 SV=3 6.74 1789.7 - 1.08E+06 - - - 3.7858 - 1.151 0.382 - 33.7 1 2 0 0.0053 11 0 0 0 1.03E+08 7.96E+07 - - - 3.197 0.9999 221125_WJC_METTL3_EV_vs_WT_F08.07825.07825.3 9.17E-06 14/60 K.ELHNTPYGTASEPSEK.A sp|Q9NXV2|KCTD5_HUMAN 1 1758.8061 4.67 113056 7825 3 1758.811418 587.276 BTB\POZ domain-containing protein KCTD5 OS=Homo sapiens OX=9606 GN=KCTD5 PE=1 SV=1 4.75 1789.8 - 488594 - - - 3.0475 - 2.371 0.546 - 203.4 1 2 0 0.0054 16 0 0 0 1.44E+10 3.08E+09 - - - 6.841 0.9998 221125_WJC_METTL3_EV_vs_WT_F08.07827.07827.2 0.000679 28-Aug K.HPPAPAEPSSDLASK.L "sp|Q9P2E9|RRBP1_HUMAN,tr|A0A087WU26|A0A087WU26_HUMAN,tr|A0A087WVV2|A0A087WVV2_HUMAN,tr|F8W7S5|F8W7S5_HUMAN" 4 1502.7365 1.49 113058 7827 2 1502.73578 752.3755 Ribosome-binding protein 1 OS=Homo sapiens OX=9606 GN=RRBP1 PE=1 SV=5 5.32 1790.1 - 74397.7 - - - -0.4938 - 1.78 0.51 - 130.7 1 2 0 -0.0007 15 0 0 0 6.78E+06 4.55E+06 - - - 4.2253 0.9998 221125_WJC_METTL3_EV_vs_WT_F08.07832.07832.2 2.16E-05 26-Nov K.SQGGVQPIPSQGGK.L sp|Q9NZB2|F120A_HUMAN 1 1338.6892 0.99 113061 7832 2 1338.689494 670.3519 Constitutive coactivator of PPAR-gamma-like protein 1 OS=Homo sapiens OX=9606 GN=FAM120A PE=1 SV=2 8.47 1790.8 - 276076 - - - 0.2361 - 2.487 0.434 - 243.3 1 2 0 0.0003 14 0 0 0 3.23E+07 3.26E+07 - - - 4.5327 0.9999 221125_WJC_METTL3_EV_vs_WT_F08.07844.07844.3 0.000148 14/40 K.DSELDKHLESR.V "sp|O75688|PPM1B_HUMAN,tr|B8ZZF0|B8ZZF0_HUMAN,tr|A0A3B3IS24|A0A3B3IS24_HUMAN,tr|C9JIR6|C9JIR6_HUMAN" 4 1327.6368 3.27 113066 7844 3 1327.637708 443.5529 Protein phosphatase 1B OS=Homo sapiens OX=9606 GN=PPM1B PE=1 SV=1 4.75 1792.4 - 776732 - - - 0.6779 - 2.54 0.492 - 450.3 1 2 1 0.0009 11 0 0 0 1.25E+08 3.82E+07 - - - 6.6732 1 221125_WJC_METTL3_EV_vs_WT_F08.07846.07846.3 2.81E-06 15/60 K.ELHNTPYGTASEPSEK[136.11].A sp|Q9NXV2|KCTD5_HUMAN 1 1766.8203 4.67 113068 7846 3 1766.820006 589.9474 BTB\POZ domain-containing protein KCTD5 OS=Homo sapiens OX=9606 GN=KCTD5 PE=1 SV=1 4.75 1792.7 - 759237 - - - -0.1426 - 2.538 0.548 - 280.1 1 2 0 -0.0003 16 0 0 0 1.44E+10 3.09E+09 - - - 7.0394 0.9856 221125_WJC_METTL3_EV_vs_WT_F08.07847.07847.2 0.00118 24-Jul R.SSPMVQVDEKGEK.V "sp|Q71RC2|LARP4_HUMAN,tr|F8W1I4|F8W1I4_HUMAN,tr|Q8TBL5|Q8TBL5_HUMAN,tr|A0A087WTL9|A0A087WTL9_HUMAN,tr|Q96J85|Q96J85_HUMAN,tr|F8VY40|F8VY40_HUMAN" 6 1432.6868 2.57 113069 7847 2 1432.682635 717.3507 La-related protein 4 OS=Homo sapiens OX=9606 GN=LARP4 PE=1 SV=3 4.68 1792.8 - 173395 - - - -2.9036 - 1.569 0.451 - 101 1 2 1 -0.0042 13 0 0 0 5.84E+06 2.27E+06 - - - 3.5268 0.9993 221125_WJC_METTL3_EV_vs_WT_F08.07848.07848.2 0.000139 22-Jul K.R[166.11]QLEEAEEEATR[166.11].A sp|P35580|MYH10_HUMAN 1 1479.7068 0.79 113070 7848 2 1479.710565 740.8607 Myosin-10 OS=Homo sapiens OX=9606 GN=MYH10 PE=1 SV=3 4.33 1792.9 - 137711 - - - 2.5174 - 2.099 0.395 - 46.8 1 2 0 0.0037 12 0 0 0 4.39E+06 5.54E+06 - - - 3.9082 0.9995 221125_WJC_METTL3_EV_vs_WT_F08.07849.07849.2 0.00044 26-Jun R.LSTQSNSNNIEPAR[166.11].T "sp|Q14669|TRIPC_HUMAN,tr|A0A6Q8PHK0|A0A6Q8PHK0_HUMAN,tr|A0A6Q8PGG9|A0A6Q8PGG9_HUMAN" 3 1539.7517 0.73 113071 7849 2 1539.75351 770.8831 E3 ubiquitin-protein ligase TRIP12 OS=Homo sapiens OX=9606 GN=TRIP12 PE=1 SV=1 6 1793.1 - 132895 - - - 1.1963 - 1.636 0.439 - 84 1 2 0 0.0018 14 0 0 0 1.88E+06 2.59E+06 - - - 3.5182 0.9996 221125_WJC_METTL3_EV_vs_WT_F08.07850.07850.2 0.000401 28-Jun K.HPPAPAEPSSDLASK[136.11].L "sp|Q9P2E9|RRBP1_HUMAN,tr|A0A087WU26|A0A087WU26_HUMAN,tr|A0A087WVV2|A0A087WVV2_HUMAN,tr|F8W7S5|F8W7S5_HUMAN" 4 1510.7507 1.49 113072 7850 2 1510.752382 756.3826 Ribosome-binding protein 1 OS=Homo sapiens OX=9606 GN=RRBP1 PE=1 SV=5 5.32 1793.2 - 111725 - - - 1.0988 - 1.611 0.456 - 83.3 1 2 0 0.0017 15 0 0 0 6.78E+06 4.55E+06 - - - 3.5809 0.9982 221125_WJC_METTL3_EV_vs_WT_F08.07853.07853.3 1.98E-05 14/48 R.HLADHGQLSGIQR[166.11].A sp|O60783|RT14_HUMAN 1 1440.7461 0.92 113073 7853 3 1441.747416 481.256 "28S ribosomal protein S14, mitochondrial OS=Homo sapiens OX=9606 GN=MRPS14 PE=1 SV=1" 6.92 1793.6 - 2.04E+06 - - - 694.9781 - 2.669 0.446 - 177.1 1 2 0 1.0013 13 0 0 0 4.68E+07 5.10E+07 - - - 5.8968 1 221125_WJC_METTL3_EV_vs_WT_F08.07856.07856.2 6.40E-09 20-Dec R.NADHSMNYQYR.- "sp|Q12906|ILF3_HUMAN,tr|K7ELV3|K7ELV3_HUMAN" 2 1397.5782 1.27 113076 7856 2 1397.58038 699.7964 Interleukin enhancer-binding factor 3 OS=Homo sapiens OX=9606 GN=ILF3 PE=1 SV=3 6.74 1794 - 324052 - - - 1.5262 - 2.339 0.707 - 483 1 2 0 0.0021 11 0 0 0 7.22E+06 5.68E+06 - - - 6.5609 0.9999 221125_WJC_METTL3_EV_vs_WT_F08.07864.07864.2 5.54E-10 13/30 K.ELHNTPYGTASEPSEK.A sp|Q9NXV2|KCTD5_HUMAN 1 1758.8061 4.58 113082 7864 2 1758.806021 880.4103 BTB\POZ domain-containing protein KCTD5 OS=Homo sapiens OX=9606 GN=KCTD5 PE=1 SV=1 4.75 1794.8 - 456967 - - - -0.021 - 2.761 0.514 - 406.2 1 2 0 0 16 0 0 0 7.07E+08 1.55E+08 - - - 5.3343 0.9998 221125_WJC_METTL3_EV_vs_WT_F08.07869.07869.3 0.00115 Nov-44 K.K[136.11]NADLNAQTVVK[136.11].V "sp|Q9Y520|PRC2C_HUMAN,tr|E7EPN9|E7EPN9_HUMAN,tr|H7C5N8|H7C5N8_HUMAN" 3 1315.7431 0.92 113085 7869 3 1315.743919 439.5883 Protein PRRC2C OS=Homo sapiens OX=9606 GN=PRRC2C PE=1 SV=4 8.59 1795.5 - 491819 - - - 0.6498 - 1.95 0.386 - 134.6 1 2 0 0.0009 12 0 0 0 7.89E+07 8.57E+07 - - - 4.6944 0.9812 221125_WJC_METTL3_EV_vs_WT_F08.07872.07872.3 0.105 Jul-36 R.SWGNNYPQHR[166.11].Q "sp|Q9BTL3|RAMAC_HUMAN,tr|A0A3B3IU46|A0A3B3IU46_HUMAN" 2 1267.5722 1.26 113088 7872 3 1267.575519 423.5313 RNA guanine-N7 methyltransferase activating subunit OS=Homo sapiens OX=9606 GN=RAMAC PE=1 SV=1 8.49 1795.8 - 260574 - - - 2.6279 - 1.197 0.27 - 68.9 1 2 0 0.0033 10 0 0 0 4.25E+07 3.36E+07 - - - 2.0745 0.9997 221125_WJC_METTL3_EV_vs_WT_F08.07875.07875.3 0.00119 Nov-44 K.DHPQQQPGMLSR.V sp|Q8WUH6|TM263_HUMAN 1 1392.6568 1.08 113089 7875 3 1392.660031 465.2262 Transmembrane protein 263 OS=Homo sapiens OX=9606 GN=TMEM263 PE=1 SV=1 6.74 1796.2 - 740424 - - - 2.297 - 2.043 0.401 - 185.8 1 2 0 0.0032 12 0 0 0 6.56E+07 6.08E+07 - - - 4.9901 0.997 221125_WJC_METTL3_EV_vs_WT_F08.07876.07876.3 2.53E-07 14/48 R.ESLC[160.03]DSPHQNLSR[166.11].P "sp|O15042|SR140_HUMAN,tr|U3KPT1|U3KPT1_HUMAN,tr|E7EW00|E7EW00_HUMAN,tr|C9JDJ7|C9JDJ7_HUMAN,tr|E7ET15|E7ET15_HUMAN,tr|H0Y8D9|H0Y8D9_HUMAN,tr|C9J5L1|C9J5L1_HUMAN" 7 1551.6975 0.28 113090 7876 3 1551.699875 518.2398 U2 snRNP-associated SURP motif-containing protein OS=Homo sapiens OX=9606 GN=U2SURP PE=1 SV=2 5.32 1796.3 - 500437 - - - 1.5145 - 2.851 0.511 - 443.3 1 1 0 0.0024 13 0 0 0 2.62E+06 9.33E+06 - - - 7.077 0.9995 221125_WJC_METTL3_EV_vs_WT_F08.07880.07880.3 0.0094 Sep-36 R.SWGNNYPQHR.Q "sp|Q9BTL3|RAMAC_HUMAN,tr|A0A3B3IU46|A0A3B3IU46_HUMAN" 2 1257.5639 0.99 113092 7880 3 1257.561949 420.1952 RNA guanine-N7 methyltransferase activating subunit OS=Homo sapiens OX=9606 GN=RAMAC PE=1 SV=1 8.49 1796.9 - 623813 - - - -1.5657 - 1.359 0.415 - 118.8 1 2 0 -0.002 10 0 0 0 7.70E+07 7.77E+07 - - - 4.0621 0.9994 221125_WJC_METTL3_EV_vs_WT_F08.07881.07881.2 5.12E-06 13/30 K.ELHNTPYGTASEPSEK[136.11].A sp|Q9NXV2|KCTD5_HUMAN 1 1766.8203 4.58 113093 7881 2 1766.816327 884.4174 BTB\POZ domain-containing protein KCTD5 OS=Homo sapiens OX=9606 GN=KCTD5 PE=1 SV=1 4.75 1797 - 325987 - - - -2.2249 - 2.678 0.338 - 449.7 1 2 0 -0.0039 16 0 0 0 7.07E+08 1.55E+08 - - - 3.9581 1 221125_WJC_METTL3_EV_vs_WT_F08.07889.07889.2 2.56E-06 16/22 K.K[136.11]NADLNAQTVVK[136.11].V "sp|Q9Y520|PRC2C_HUMAN,tr|E7EPN9|E7EPN9_HUMAN,tr|H7C5N8|H7C5N8_HUMAN" 3 1315.7431 1.43 113098 7889 2 1315.742639 658.8788 Protein PRRC2C OS=Homo sapiens OX=9606 GN=PRRC2C PE=1 SV=4 8.59 1797.9 - 542366 - - - -0.323 - 3 0.566 - 744.1 1 2 0 -0.0004 12 0 0 0 4.06E+07 2.85E+07 - - - 6.112 0.9995 221125_WJC_METTL3_EV_vs_WT_F08.07890.07890.3 2.23E-05 Sep-44 R.LDYHKEQAAQLR.N sp|P40938|RFC3_HUMAN 1 1470.7579 0.52 113099 7890 3 1470.755438 491.2599 Replication factor C subunit 3 OS=Homo sapiens OX=9606 GN=RFC3 PE=1 SV=2 6.75 1798 - 368746 - - - -1.6916 - 2.196 0.424 - 82.5 1 2 1 -0.0025 12 0 0 0 6.81E+06 1.32E+07 - - - 5.4469 0.9972 221125_WJC_METTL3_EV_vs_WT_F08.07896.07896.3 0.00377 Nov-48 K.IQDKEGIPPDQQR.L "sp|P62979|RS27A_HUMAN,sp|P0CG48|UBC_HUMAN,sp|P0CG48|UBC_HUMAN,sp|P0CG48|UBC_HUMAN,sp|P0CG48|UBC_HUMAN,sp|P0CG48|UBC_HUMAN,sp|P0CG48|UBC_HUMAN,sp|P0CG48|UBC_HUMAN,sp|P0CG48|UBC_HUMAN,sp|P0CG48|UBC_HUMAN,sp|P0CG47|UBB_HUMAN,sp|P0CG47|UBB_HUMAN,sp|P0CG47|UBB_HUMAN,sp|P62987|RL40_HUMAN,tr|F5H388|F5H388_HUMAN,tr|F5H388|F5H388_HUMAN,tr|F5GYU3|F5GYU3_HUMAN,tr|F5GYU3|F5GYU3_HUMAN,tr|B4DV12|B4DV12_HUMAN,tr|B4DV12|B4DV12_HUMAN,tr|J3QSA3|J3QSA3_HUMAN,tr|Q5PY61|Q5PY61_HUMAN,tr|Q5PY61|Q5PY61_HUMAN,tr|Q5PY61|Q5PY61_HUMAN,tr|F5H2Z3|F5H2Z3_HUMAN,tr|F5H2Z3|F5H2Z3_HUMAN,tr|M0R2S1|M0R2S1_HUMAN,tr|J3QS39|J3QS39_HUMAN,tr|J3QTR3|J3QTR3_HUMAN,tr|Q96C32|Q96C32_HUMAN,tr|Q96C32|Q96C32_HUMAN,tr|Q96C32|Q96C32_HUMAN,tr|Q96C32|Q96C32_HUMAN,tr|M0R1V7|M0R1V7_HUMAN,tr|F5H747|F5H747_HUMAN,tr|F5H747|F5H747_HUMAN,tr|F5GXK7|F5GXK7_HUMAN,tr|F5GXK7|F5GXK7_HUMAN,tr|M0R1M6|M0R1M6_HUMAN,tr|F5H6Q2|F5H6Q2_HUMAN,tr|F5H6Q2|F5H6Q2_HUMAN,tr|F5GZ39|F5GZ39_HUMAN,tr|J3QKN0|J3QKN0_HUMAN,tr|J3QKN0|J3QKN0_HUMAN,tr|F5H265|F5H265_HUMAN,tr|F5H265|F5H265_HUMAN,tr|A0A2R8Y422|A0A2R8Y422_HUMAN" 47 1522.774 0.76 113104 7896 3 1522.771627 508.5986 Ubiquitin-40S ribosomal protein S27a OS=Homo sapiens OX=9606 GN=RPS27A PE=1 SV=2 4.56 1798.8 - 1.09E+06 - - - -1.5386 - 2.033 0.308 - 193.1 1 2 1 -0.0023 13 0 0 0 9.98E+07 1.32E+08 - - - 3.8969 0.9998 221125_WJC_METTL3_EV_vs_WT_F08.07899.07899.3 0.000478 15/36 R.KIENIHIGEK.K "sp|O00203|AP3B1_HUMAN,tr|H0YBD0|H0YBD0_HUMAN" 2 1179.6612 0.81 113106 7899 3 1179.658791 394.2277 AP-3 complex subunit beta-1 OS=Homo sapiens OX=9606 GN=AP3B1 PE=1 SV=3 6.76 1799.2 - 957508 - - - -2.0184 - 2.718 0.338 - 245.2 1 2 0 -0.0024 10 0 0 0 3.44E+07 4.24E+07 - - - 5.2278 0.9954 221125_WJC_METTL3_EV_vs_WT_F08.07900.07900.3 0.0581 Jul-40 R.NADHSMNYQYR[166.11].- "sp|Q12906|ILF3_HUMAN,tr|K7ELV3|K7ELV3_HUMAN" 2 1407.5865 1.29 113107 7900 3 1407.585556 470.2028 Interleukin enhancer-binding factor 3 OS=Homo sapiens OX=9606 GN=ILF3 PE=1 SV=3 6.74 1799.2 - 3.38E+06 - - - -0.6827 - 1.023 0.33 - 64 1 2 0 -0.001 11 0 0 0 1.03E+08 7.96E+07 - - - 2.2835 0.9997 221125_WJC_METTL3_EV_vs_WT_F08.07903.07903.2 4.76E-05 24-Oct K.SQGVQPIPSQGGK.L tr|A0A494C0Y9|A0A494C0Y9_HUMAN 1 1281.6677 0.92 113110 7903 2 1281.665096 641.8411 Constitutive coactivator of PPAR-gamma-like protein 1 (Fragment) OS=Homo sapiens OX=9606 GN=FAM120A PE=1 SV=1 8.47 1799.6 - 341115 - - - -2.0427 - 2.157 0.481 - 271.7 1 2 0 -0.0026 13 0 0 0 5.11E+06 5.53E+06 - - - 4.5658 1 221125_WJC_METTL3_EV_vs_WT_F08.07906.07906.2 6.91E-07 18/22 K.KNADLNAQTVVK.V "sp|Q9Y520|PRC2C_HUMAN,tr|E7EPN9|E7EPN9_HUMAN,tr|H7C5N8|H7C5N8_HUMAN" 3 1299.7147 1.43 113111 7906 2 1299.713434 650.8646 Protein PRRC2C OS=Homo sapiens OX=9606 GN=PRRC2C PE=1 SV=4 8.59 1800 - 969421 - - - -0.9464 - 3.167 0.512 - 1057.9 1 2 0 -0.0012 12 0 0 0 4.06E+07 2.85E+07 - - - 5.8554 0.9324 221125_WJC_METTL3_EV_vs_WT_F08.07917.07917.3 0.163 Sep-44 R.EK[136.11]VDSQYPPVQR[166.11].L sp|P49790|NU153_HUMAN 1 1462.7535 1.71 113118 7917 3 1462.751146 488.5918 Nuclear pore complex protein Nup153 OS=Homo sapiens OX=9606 GN=NUP153 PE=1 SV=2 6.17 1801.2 - 768245 - - - -1.6182 - 1.722 0.152 - 74.5 1 2 1 -0.0024 12 0 0 0 7.25E+07 4.23E+07 - - - 1.7405 0.9999 221125_WJC_METTL3_EV_vs_WT_F08.07921.07921.3 1.62E-08 13/52 R.AK[136.11]EEQQDDTVYMGK[136.11].V "sp|Q14203|DCTN1_HUMAN,tr|A0A804CDA6|A0A804CDA6_HUMAN,tr|E7EX90|E7EX90_HUMAN,tr|A0A7P0Z4C3|A0A7P0Z4C3_HUMAN,tr|E7EWF7|E7EWF7_HUMAN" 5 1656.7636 2 113120 7921 3 1656.763056 553.2618 Dynactin subunit 1 OS=Homo sapiens OX=9606 GN=DCTN1 PE=1 SV=3 4.32 1801.8 - 856894 - - - -0.329 - 2.486 0.58 - 230.1 1 2 1 -0.0005 14 0 0 0 9.98E+07 4.99E+07 - - - 7.4264 1 221125_WJC_METTL3_EV_vs_WT_F08.07923.07923.3 1.21E-05 13/44 K.TFSGQTHGFVHR[166.11].K sp|Q96DG6|CMBL_HUMAN 1 1382.6719 1.06 113121 7923 3 1382.670607 461.8979 Carboxymethylenebutenolidase homolog OS=Homo sapiens OX=9606 GN=CMBL PE=1 SV=1 9.47 1802 - 4.83E+06 - - - -0.9366 - 2.382 0.451 - 209.2 1 2 0 -0.0013 12 0 0 0 2.20E+08 2.08E+08 - - - 5.9736 0.9998 221125_WJC_METTL3_EV_vs_WT_F08.07927.07927.2 0.00172 24-Dec K.EVYQQQQYGSGGR.G "sp|Q99729|ROAA_HUMAN,tr|D6R9P3|D6R9P3_HUMAN,tr|D6RD18|D6RD18_HUMAN,tr|D6RBZ0|D6RBZ0_HUMAN" 4 1498.6801 1.52 113125 7927 2 1498.677051 750.3473 Heterogeneous nuclear ribonucleoprotein A\B OS=Homo sapiens OX=9606 GN=HNRNPAB PE=1 SV=2 6.1 1802.4 - 705808 - - - -2.0144 - 2.261 0.583 - 467.3 1 2 0 -0.003 13 0 0 0 2.04E+07 1.34E+07 - - - 5.4399 0.9999 221125_WJC_METTL3_EV_vs_WT_F08.07935.07935.3 3.60E-05 Dec-44 K.KNADLNAQTVVK.V "sp|Q9Y520|PRC2C_HUMAN,tr|E7EPN9|E7EPN9_HUMAN,tr|H7C5N8|H7C5N8_HUMAN" 3 1299.7147 0.93 113128 7935 3 1299.713854 434.2455 Protein PRRC2C OS=Homo sapiens OX=9606 GN=PRRC2C PE=1 SV=4 8.59 1803.5 - 3.06E+06 - - - -0.6232 - 2.116 0.429 - 208.5 1 2 0 -0.0008 12 0 0 0 7.81E+07 8.37E+07 - - - 5.4003 1 221125_WJC_METTL3_EV_vs_WT_F08.07946.07946.3 0.000509 14/40 R.R[166.11]QAVDVSPLR[166.11]R[166.11].V "sp|P46782|RS5_HUMAN,tr|M0QZN2|M0QZN2_HUMAN,tr|M0R0F0|M0R0F0_HUMAN,tr|M0R0R2|M0R0R2_HUMAN" 4 1325.767 0.85 113134 7946 3 1325.765999 442.9296 40S ribosomal protein S5 OS=Homo sapiens OX=9606 GN=RPS5 PE=1 SV=4 11.7 1804.8 - 8.39E+06 - - - -0.7746 - 2.413 0.478 - 305.1 1 2 0 -0.001 11 0 0 0 5.45E+08 6.40E+08 - - - 6.3713 1 221125_WJC_METTL3_EV_vs_WT_F08.07958.07958.3 0.000257 17/60 K.AQELGHSQSALASAQR[166.11].E "sp|Q14980|NUMA1_HUMAN,tr|A0A087WY61|A0A087WY61_HUMAN,tr|H0YFY6|H0YFY6_HUMAN" 3 1662.8313 1.06 113140 7958 3 1662.833389 555.2844 Nuclear mitotic apparatus protein 1 OS=Homo sapiens OX=9606 GN=NUMA1 PE=1 SV=2 6.79 1806.1 - 548886 - - - 1.2467 - 3.181 0.498 - 385.9 1 2 0 0.0021 16 0 0 0 3.68E+07 3.48E+07 - - - 7.0608 0.9326 221125_WJC_METTL3_EV_vs_WT_F08.07966.07966.2 4.25E-05 18-Dec F.SGQTHGFVHR.K sp|Q96DG6|CMBL_HUMAN 1 1124.5475 4.48 113144 7966 2 1124.543896 563.281 Carboxymethylenebutenolidase homolog OS=Homo sapiens OX=9606 GN=CMBL PE=1 SV=1 9.51 1807 - 390779 - - - -3.2395 - 1.81 0.437 - 584.1 1 1 0 -0.0036 10 0 0 0 3.87E+07 8.64E+06 - - - 3.9237 1 221125_WJC_METTL3_EV_vs_WT_F08.07968.07968.3 0.0192 17/40 R.RQAVDVSPLRR.V "sp|P46782|RS5_HUMAN,tr|M0QZN2|M0QZN2_HUMAN,tr|M0R0F0|M0R0F0_HUMAN,tr|M0R0R2|M0R0R2_HUMAN" 4 1295.7422 0.85 113145 7968 3 1295.740324 432.9213 40S ribosomal protein S5 OS=Homo sapiens OX=9606 GN=RPS5 PE=1 SV=4 11.7 1807.2 - 1.25E+07 - - - -1.4602 - 2.577 0.459 - 500 1 2 0 -0.0019 11 0 0 0 5.45E+08 6.40E+08 - - - 6.3461 1 221125_WJC_METTL3_EV_vs_WT_F08.07973.07973.3 1.77E-06 13/44 K.TFSGQTHGFVHR.K sp|Q96DG6|CMBL_HUMAN 1 1372.6636 1.06 113148 7973 3 1372.662341 458.5618 Carboxymethylenebutenolidase homolog OS=Homo sapiens OX=9606 GN=CMBL PE=1 SV=1 9.47 1807.8 - 3.17E+06 - - - -0.9405 - 2.175 0.54 - 217.4 1 2 0 -0.0013 12 0 0 0 2.20E+08 2.08E+08 - - - 6.7139 1 221125_WJC_METTL3_EV_vs_WT_F08.07975.07975.3 3.51E-12 20/60 K.AQELGHSQSALASAQR.E "sp|Q14980|NUMA1_HUMAN,tr|A0A087WY61|A0A087WY61_HUMAN,tr|H0YFY6|H0YFY6_HUMAN" 3 1652.823 1.06 113149 7975 3 1652.822788 551.9483 Nuclear mitotic apparatus protein 1 OS=Homo sapiens OX=9606 GN=NUMA1 PE=1 SV=2 6.79 1808.1 - 1.53E+06 - - - -0.1561 - 3.654 0.63 - 641.7 1 2 0 -0.0003 16 0 0 0 3.68E+07 3.48E+07 - - - 8.8887 0.9999 221125_WJC_METTL3_EV_vs_WT_F08.07980.07980.3 0.000113 15/44 K.LDPHNHVLYSNR[166.11].S "sp|P31948|STIP1_HUMAN,tr|F5GXD8|F5GXD8_HUMAN,tr|F5H783|F5H783_HUMAN" 3 1473.7352 2.87 113151 7980 3 1473.731822 492.2524 Stress-induced-phosphoprotein 1 OS=Homo sapiens OX=9606 GN=STIP1 PE=1 SV=1 6.92 1808.8 - 1.18E+06 - - - -2.3125 - 2.578 0.461 - 420.1 1 2 0 -0.0034 12 0 0 0 3.87E+08 1.35E+08 - - - 6.3037 0.9998 221125_WJC_METTL3_EV_vs_WT_F08.07984.07984.3 7.10E-07 15/48 R.GNTQATSHSFDVR.V sp|Q5SWX8|ODR4_HUMAN 1 1418.6539 1.34 113153 7984 3 1418.659727 473.8919 Protein odr-4 homolog OS=Homo sapiens OX=9606 GN=ODR4 PE=1 SV=1 6.74 1809.2 - 702333 - - - 4.1391 - 2.563 0.517 - 282.2 1 2 0 0.0059 13 0 0 0 8.83E+07 6.59E+07 - - - 6.8542 0.9994 221125_WJC_METTL3_EV_vs_WT_F08.07988.07988.3 0.00381 14/44 K.LDPHNHVLYSNR.S "sp|P31948|STIP1_HUMAN,tr|F5GXD8|F5GXD8_HUMAN,tr|F5H783|F5H783_HUMAN" 3 1463.727 1.62 113155 7988 3 1463.719406 488.9163 Stress-induced-phosphoprotein 1 OS=Homo sapiens OX=9606 GN=STIP1 PE=1 SV=1 6.92 1809.8 - 1.84E+06 - - - -5.1608 - 2.509 0.472 - 232 1 2 0 -0.0076 12 0 0 0 2.10E+08 1.30E+08 - - - 6.35 0.9992 221125_WJC_METTL3_EV_vs_WT_F08.07989.07989.3 0.0242 Sep-48 R.GNTQATSHSFDVR[166.11].V sp|Q5SWX8|ODR4_HUMAN 1 1428.6621 1.36 113156 7989 3 1428.659372 477.228 Protein odr-4 homolog OS=Homo sapiens OX=9606 GN=ODR4 PE=1 SV=1 6.74 1809.8 - 959720 - - - -1.927 - 1.902 0.32 - 84.5 1 2 0 -0.0028 13 0 0 0 8.80E+07 6.47E+07 - - - 3.85 0.9999 221125_WJC_METTL3_EV_vs_WT_F08.07990.07990.3 0.00287 15/48 R.ALLQQQPEDDSK[136.11]R[166.11].S sp|Q9UHB9|SRP68_HUMAN 1 1544.7914 0.71 113157 7990 3 1544.791313 515.9377 Signal recognition particle subunit SRP68 OS=Homo sapiens OX=9606 GN=SRP68 PE=1 SV=2 4.56 1809.9 - 1.64E+06 - - - -0.0272 - 2.501 0.369 - 354.8 1 2 0 0 13 0 0 0 4.24E+07 5.94E+07 - - - 5.1394 0.9997 221125_WJC_METTL3_EV_vs_WT_F08.07992.07992.3 5.47E-05 14/52 R.AKEEQQDDTVYMGK.V "sp|Q14203|DCTN1_HUMAN,tr|A0A804CDA6|A0A804CDA6_HUMAN,tr|E7EX90|E7EX90_HUMAN,tr|A0A7P0Z4C3|A0A7P0Z4C3_HUMAN,tr|E7EWF7|E7EWF7_HUMAN" 5 1640.7352 2 113158 7992 3 1640.734452 547.919 Dynactin subunit 1 OS=Homo sapiens OX=9606 GN=DCTN1 PE=1 SV=3 4.32 1810.1 - 1.23E+06 - - - -0.4565 - 2.059 0.464 - 252.9 1 2 1 -0.0008 14 0 0 0 9.99E+07 4.99E+07 - - - 5.6323 1 221125_WJC_METTL3_EV_vs_WT_F08.07993.07993.3 5.19E-07 16/52 K.ENAEQGEVDMESHR.N sp|P14209|CD99_HUMAN 1 1629.6689 1.41 113159 7993 3 1629.66699 544.2302 CD99 antigen OS=Homo sapiens OX=9606 GN=CD99 PE=1 SV=1 4.25 1810.3 - 661777 - - - -1.18 - 2.697 0.587 - 449.4 1 2 0 -0.0019 14 0 0 0 1.52E+07 1.08E+07 - - - 7.7206 0.9999 221125_WJC_METTL3_EV_vs_WT_F08.07996.07996.3 0.224 15/44 R.K[136.11]GHAVGDIPGVR[166.11].F "sp|P62266|RS23_HUMAN,tr|D6RD47|D6RD47_HUMAN" 2 1222.6901 1.36 113160 7996 3 1222.689236 408.5707 40S ribosomal protein S23 OS=Homo sapiens OX=9606 GN=RPS23 PE=1 SV=3 8.75 1810.6 - 1.26E+06 - - - -0.7271 - 2.598 0.382 - 346.7 1 2 0 -0.0009 12 0 0 0 1.28E+08 9.44E+07 - - - 5.4451 0.9957 221125_WJC_METTL3_EV_vs_WT_F08.07998.07998.3 0.00729 Oct-52 K.QDGEC[160.03]GTLSKGELK.E sp|Q5D862|FILA2_HUMAN 1 1520.7141 98.74 113162 7998 3 1520.716081 507.912 Filaggrin-2 OS=Homo sapiens OX=9606 GN=FLG2 PE=1 SV=1 4.68 1810.8 - 1.27E+06 - - - 1.3211 - 1.739 0.317 - 108.2 1 2 1 0.002 14 0 0 0 3.76E+07 3.81E+05 - - - 3.5441 0.9996 221125_WJC_METTL3_EV_vs_WT_F08.07999.07999.3 0.00369 Sep-48 K.ETGYVVER[166.11]PSTTK[136.11].D "sp|Q9NYF8|BCLF1_HUMAN,tr|E9PKI6|E9PKI6_HUMAN,tr|A0A1W2PQ43|A0A1W2PQ43_HUMAN,tr|E9PK91|E9PK91_HUMAN,tr|E9PK09|E9PK09_HUMAN,tr|E9PQN2|E9PQN2_HUMAN" 6 1483.7637 2.13 113163 7999 3 1483.765605 495.5952 Bcl-2-associated transcription factor 1 OS=Homo sapiens OX=9606 GN=BCLAF1 PE=1 SV=2 6.24 1810.9 - 895804 - - - 1.2549 - 1.821 0.361 - 65.3 1 2 0 0.0019 13 0 0 0 4.82E+09 2.27E+09 - - - 4.1894 0.9998 221125_WJC_METTL3_EV_vs_WT_F08.08000.08000.2 2.17E-07 30-Nov R.QAEQLSAAGEGGDAGR[166.11].M "sp|Q9NRX1|PNO1_HUMAN,tr|F8WBJ6|F8WBJ6_HUMAN" 2 1525.6996 0.72 113164 8000 2 1525.696663 763.8571 RNA-binding protein PNO1 OS=Homo sapiens OX=9606 GN=PNO1 PE=1 SV=1 4.14 1811 - 273396 - - - -1.9466 - 2.372 0.606 - 343.3 1 2 0 -0.003 16 0 0 0 4.15E+06 5.79E+06 - - - 5.6395 0.9863 221125_WJC_METTL3_EV_vs_WT_F08.08003.08003.3 0.000367 Oct-40 K.EWSQHINGASH.S "sp|P43243|MATR3_HUMAN,tr|A8MXP9|A8MXP9_HUMAN,tr|D6R991|D6R991_HUMAN,tr|A0A0R4J2E8|A0A0R4J2E8_HUMAN,tr|H0Y8T4|H0Y8T4_HUMAN,tr|D6REM6|D6REM6_HUMAN" 6 1264.5585 - 113165 8003 3 1264.557896 422.5268 Matrin-3 OS=Homo sapiens OX=9606 GN=MATR3 PE=1 SV=2 5.99 1811.4 - 3.52E+06 - - - -0.4761 - 1.634 0.448 - 154.3 1 1 0 -0.0006 11 0 0 0 - - - - - 4.9295 1 221125_WJC_METTL3_EV_vs_WT_F08.08008.08008.2 2.20E-08 30-Oct R.QAEQLSAAGEGGDAGR.M "sp|Q9NRX1|PNO1_HUMAN,tr|F8WBJ6|F8WBJ6_HUMAN" 2 1515.6914 0.72 113168 8008 2 1515.690423 758.853 RNA-binding protein PNO1 OS=Homo sapiens OX=9606 GN=PNO1 PE=1 SV=1 4.14 1812.1 - 168585 - - - -0.6202 - 2.374 0.663 - 271 1 2 0 -0.0009 16 0 0 0 4.15E+06 5.79E+06 - - - 6.0632 0.9998 221125_WJC_METTL3_EV_vs_WT_F08.08018.08018.2 4.49E-06 30-Aug R.SPQPVC[160.03]SPAGSEGTPK[136.11].G "sp|Q6KC79|NIPBL_HUMAN,tr|A0A590UJS4|A0A590UJS4_HUMAN" 2 1605.7548 1.97 113173 8018 2 1605.753851 803.8847 Nipped-B-like protein OS=Homo sapiens OX=9606 GN=NIPBL PE=1 SV=2 5.72 1813.3 - 224555 - - - -0.6041 - 1.801 0.55 - 183 1 2 0 -0.001 16 0 0 0 1.55E+07 7.87E+06 - - - 4.5495 0.9914 221125_WJC_METTL3_EV_vs_WT_F08.08019.08019.2 0.168 22-May K.LDPHNHVLYSNR[166.11].S "sp|P31948|STIP1_HUMAN,tr|F5GXD8|F5GXD8_HUMAN,tr|F5H783|F5H783_HUMAN" 3 1473.7352 14.07 113174 8019 2 1473.734628 737.8749 Stress-induced-phosphoprotein 1 OS=Homo sapiens OX=9606 GN=STIP1 PE=1 SV=1 6.92 1813.4 - 0 - - - -0.4085 - 0.979 0.236 - 83.6 1 2 0 -0.0006 12 0 0 0 1.07E+07 7.63E+05 - - - 0.7281 1 221125_WJC_METTL3_EV_vs_WT_F08.08022.08022.2 1.46E-08 20-Oct K.EWSQHINGASH.S "sp|P43243|MATR3_HUMAN,tr|A8MXP9|A8MXP9_HUMAN,tr|D6R991|D6R991_HUMAN,tr|A0A0R4J2E8|A0A0R4J2E8_HUMAN,tr|H0Y8T4|H0Y8T4_HUMAN,tr|D6REM6|D6REM6_HUMAN" 6 1264.5585 - 113175 8022 2 1264.559344 633.2865 Matrin-3 OS=Homo sapiens OX=9606 GN=MATR3 PE=1 SV=2 5.99 1813.8 - 774749 - - - 0.669 - 2.378 0.623 - 280.1 1 1 0 0.0008 11 0 0 0 - - - - - 5.9856 0.9999 221125_WJC_METTL3_EV_vs_WT_F08.08023.08023.2 0.00739 13/30 R.SPQPVC[160.03]SPAGSEGTPK.G "sp|Q6KC79|NIPBL_HUMAN,tr|A0A590UJS4|A0A590UJS4_HUMAN" 2 1597.7406 1.97 113176 8023 2 1597.742693 799.8776 Nipped-B-like protein OS=Homo sapiens OX=9606 GN=NIPBL PE=1 SV=2 5.72 1813.9 - 282133 - - - 1.2968 - 2.498 0.549 - 436.4 1 2 0 0.0021 16 0 0 0 1.55E+07 7.87E+06 - - - 5.346 0.9989 221125_WJC_METTL3_EV_vs_WT_F08.08026.08026.3 0.000536 Nov-40 K.NRETHEIVALK.R sp|Q00535|CDK5_HUMAN 1 1308.715 1.27 113177 8026 3 1308.714514 437.2456 Cyclin-dependent-like kinase 5 OS=Homo sapiens OX=9606 GN=CDK5 PE=1 SV=3 6.76 1814.3 - 349803 - - - -0.3706 - 1.608 0.407 - 178.3 1 2 1 -0.0005 11 0 0 0 7.57E+06 5.94E+06 - - - 4.4269 0.9982 221125_WJC_METTL3_EV_vs_WT_F08.08027.08027.2 0.0444 24-Jun K.TSDVNETQPPQSE.- sp|P35580|MYH10_HUMAN 1 1430.6161 - 113178 8027 2 1430.616863 716.3153 Myosin-10 OS=Homo sapiens OX=9606 GN=MYH10 PE=1 SV=3 3.91 1814.5 - 226741 - - - 0.511 - 1.258 0.312 - 80.1 1 2 0 0.0007 13 0 0 0 - - - - - 1.9343 0.9998 221125_WJC_METTL3_EV_vs_WT_F08.08033.08033.2 4.01E-06 13/24 K.ETGYVVERPSTTK.D "sp|Q9NYF8|BCLF1_HUMAN,tr|E9PKI6|E9PKI6_HUMAN,tr|A0A1W2PQ43|A0A1W2PQ43_HUMAN,tr|E9PK91|E9PK91_HUMAN,tr|E9PK09|E9PK09_HUMAN,tr|E9PQN2|E9PQN2_HUMAN" 6 1465.7413 2.15 113181 8033 2 1465.74186 733.8779 Bcl-2-associated transcription factor 1 OS=Homo sapiens OX=9606 GN=BCLAF1 PE=1 SV=2 6.24 1815.2 - 350361 - - - 0.4005 - 2.189 0.423 - 534.3 1 2 0 0.0006 13 0 0 0 5.48E+08 2.54E+08 - - - 4.1758 0.9994 221125_WJC_METTL3_EV_vs_WT_F08.08038.08038.2 3.04E-07 13/24 K.ETGYVVER[166.11]PSTTK[136.11].D "sp|Q9NYF8|BCLF1_HUMAN,tr|E9PKI6|E9PKI6_HUMAN,tr|A0A1W2PQ43|A0A1W2PQ43_HUMAN,tr|E9PK91|E9PK91_HUMAN,tr|E9PK09|E9PK09_HUMAN,tr|E9PQN2|E9PQN2_HUMAN" 6 1483.7637 2.15 113184 8038 2 1483.768839 742.8891 Bcl-2-associated transcription factor 1 OS=Homo sapiens OX=9606 GN=BCLAF1 PE=1 SV=2 6.24 1815.9 - 261188 - - - 3.4345 - 2.343 0.572 - 606.2 1 2 0 0.0051 13 0 0 0 5.48E+08 2.54E+08 - - - 5.4494 0.9571 221125_WJC_METTL3_EV_vs_WT_F08.08041.08041.3 0.0824 Jun-56 R.DAGADLDK[136.11]PEPTC[160.03]GR[166.11].S "sp|Q15653|IKBB_HUMAN,tr|I3L4X3|I3L4X3_HUMAN,tr|G5E9C2|G5E9C2_HUMAN" 3 1618.7376 21.85 113187 8041 3 1618.73444 540.5865 NF-kappa-B inhibitor beta OS=Homo sapiens OX=9606 GN=NFKBIB PE=1 SV=2 4.23 1816.3 - 163626 - - - -1.9552 - 1.143 0.213 - 38.3 1 2 0 -0.0032 15 0 0 0 7.37E+07 3.37E+06 - - - 1.2626 0.999 221125_WJC_METTL3_EV_vs_WT_F08.08045.08045.3 0.000815 15/48 K.IQDK[136.11]EGIPPDQQR[166.11].L "sp|P62979|RS27A_HUMAN,sp|P0CG48|UBC_HUMAN,sp|P0CG48|UBC_HUMAN,sp|P0CG48|UBC_HUMAN,sp|P0CG48|UBC_HUMAN,sp|P0CG48|UBC_HUMAN,sp|P0CG48|UBC_HUMAN,sp|P0CG48|UBC_HUMAN,sp|P0CG48|UBC_HUMAN,sp|P0CG48|UBC_HUMAN,sp|P0CG47|UBB_HUMAN,sp|P0CG47|UBB_HUMAN,sp|P0CG47|UBB_HUMAN,sp|P62987|RL40_HUMAN,tr|F5H388|F5H388_HUMAN,tr|F5H388|F5H388_HUMAN,tr|F5GYU3|F5GYU3_HUMAN,tr|F5GYU3|F5GYU3_HUMAN,tr|B4DV12|B4DV12_HUMAN,tr|B4DV12|B4DV12_HUMAN,tr|J3QSA3|J3QSA3_HUMAN,tr|Q5PY61|Q5PY61_HUMAN,tr|Q5PY61|Q5PY61_HUMAN,tr|Q5PY61|Q5PY61_HUMAN,tr|F5H2Z3|F5H2Z3_HUMAN,tr|F5H2Z3|F5H2Z3_HUMAN,tr|M0R2S1|M0R2S1_HUMAN,tr|J3QS39|J3QS39_HUMAN,tr|J3QTR3|J3QTR3_HUMAN,tr|Q96C32|Q96C32_HUMAN,tr|Q96C32|Q96C32_HUMAN,tr|Q96C32|Q96C32_HUMAN,tr|Q96C32|Q96C32_HUMAN,tr|M0R1V7|M0R1V7_HUMAN,tr|F5H747|F5H747_HUMAN,tr|F5H747|F5H747_HUMAN,tr|F5GXK7|F5GXK7_HUMAN,tr|F5GXK7|F5GXK7_HUMAN,tr|M0R1M6|M0R1M6_HUMAN,tr|F5H6Q2|F5H6Q2_HUMAN,tr|F5H6Q2|F5H6Q2_HUMAN,tr|F5GZ39|F5GZ39_HUMAN,tr|J3QKN0|J3QKN0_HUMAN,tr|J3QKN0|J3QKN0_HUMAN,tr|F5H265|F5H265_HUMAN,tr|F5H265|F5H265_HUMAN,tr|A0A2R8Y422|A0A2R8Y422_HUMAN" 47 1540.7964 0.64 113188 8045 3 1540.797578 514.6061 Ubiquitin-40S ribosomal protein S27a OS=Homo sapiens OX=9606 GN=RPS27A PE=1 SV=2 4.56 1816.8 - 1.54E+06 - - - 0.7386 - 2.297 0.329 - 340.2 1 2 1 0.0011 13 0 0 0 3.29E+07 5.12E+07 - - - 4.4624 0.9742 221125_WJC_METTL3_EV_vs_WT_F08.08046.08046.3 0.0222 Dec-32 H.RHEGVFIC[160.03]R.G "sp|P22087|FBRL_HUMAN,tr|M0R299|M0R299_HUMAN,tr|M0R0P1|M0R0P1_HUMAN,tr|M0R1H0|M0R1H0_HUMAN,tr|M0QXL5|M0QXL5_HUMAN,tr|M0R2Q4|M0R2Q4_HUMAN,tr|M0R2B0|M0R2B0_HUMAN,tr|M0R2U2|M0R2U2_HUMAN" 8 1172.5873 0.87 113189 8046 3 1172.587435 391.8697 rRNA 2'-O-methyltransferase fibrillarin OS=Homo sapiens OX=9606 GN=FBL PE=1 SV=2 8.26 1817 - 373100 - - - 0.1185 - 1.747 0.372 - 218.9 1 1 0 0.0001 9 0 0 0 1.07E+07 1.23E+07 - - - 4.3688 1 221125_WJC_METTL3_EV_vs_WT_F08.08054.08054.3 1.42E-05 13/44 R.SQYEQLAEQNRK.D "sp|P13645|K1C10_HUMAN,tr|A0A1B0GVI3|A0A1B0GVI3_HUMAN" 2 1492.727 66736.67 113195 8054 3 1492.72843 498.5829 "Keratin, type I cytoskeletal 10 OS=Homo sapiens OX=9606 GN=KRT10 PE=1 SV=6" 5.86 1817.9 - 6.77E+06 - - - 0.9446 - 2.518 0.504 - 307 1 2 0 0.0014 12 0 0 0 2.21E+10 3.31E+05 - - - 6.7184 0.9929 221125_WJC_METTL3_EV_vs_WT_F08.08057.08057.3 0.241 Jul-32 K.EMRDELHVR.G sp|O94874|UFL1_HUMAN 1 1183.5768 0.79 113198 8057 3 1183.575812 395.5329 E3 UFM1-protein ligase 1 OS=Homo sapiens OX=9606 GN=UFL1 PE=1 SV=2 5.45 1818.3 - 237103 - - - -0.8272 - 1.5 0.291 - 63.5 1 2 1 -0.001 9 0 0 0 3.28E+06 4.14E+06 - - - 3.0061 0.9997 221125_WJC_METTL3_EV_vs_WT_F08.08060.08060.2 0.000123 20-Oct K.K[136.11]SDMEWTSSSK[136.11].L "sp|Q14527|HLTF_HUMAN,tr|H7C5K0|H7C5K0_HUMAN,tr|A0A0C4DGA6|A0A0C4DGA6_HUMAN" 3 1300.594 1.7 113201 8060 2 1300.591334 651.3043 Helicase-like transcription factor OS=Homo sapiens OX=9606 GN=HLTF PE=1 SV=2 6.07 1818.7 - 142274 - - - -2.0629 - 1.875 0.544 - 293.3 1 2 0 -0.0027 11 0 0 0 4.39E+06 2.59E+06 - - - 4.7587 0.999 221125_WJC_METTL3_EV_vs_WT_F08.08064.08064.3 0.00183 13/40 R.NTKQEIAEINR.M "sp|P48668|K2C6C_HUMAN,sp|P04259|K2C6B_HUMAN,sp|P02538|K2C6A_HUMAN" 3 1314.6892 213.08 113203 8064 3 1314.690631 439.237 "Keratin, type II cytoskeletal 6C OS=Homo sapiens OX=9606 GN=KRT6C PE=1 SV=3" 6.14 1819.1 - 2.61E+06 - - - 1.1052 - 2.515 0.312 - 316.8 1 2 1 0.0015 11 0 0 0 2.99E+09 1.40E+07 - - - 4.6381 0.9998 221125_WJC_METTL3_EV_vs_WT_F08.08067.08067.2 9.58E-05 13/22 R.SQYEQLAEQNRK.D "sp|P13645|K1C10_HUMAN,tr|A0A1B0GVI3|A0A1B0GVI3_HUMAN" 2 1492.727 999 113206 8067 2 1492.729945 747.3708 "Keratin, type I cytoskeletal 10 OS=Homo sapiens OX=9606 GN=KRT10 PE=1 SV=6" 5.86 1819.4 - 674915 - - - 1.9595 - 2.615 0.489 - 566.5 1 2 0 0.0029 12 0 0 0 1.28E+09 0.00E+00 - - - 5.1811 0.9998 221125_WJC_METTL3_EV_vs_WT_F08.08069.08069.2 3.97E-07 Oct-32 K.QGPVSQSATQQPVTADK.Q "sp|Q9BTA9|WAC_HUMAN,tr|A0A7P0T961|A0A7P0T961_HUMAN,tr|A0A0A0MRT2|A0A0A0MRT2_HUMAN,tr|J3QTA0|J3QTA0_HUMAN" 4 1740.8642 2.68 113208 8069 2 1740.866787 871.4394 WW domain-containing adapter protein with coiled-coil OS=Homo sapiens OX=9606 GN=WAC PE=1 SV=3 5.84 1819.6 - 229541 - - - 1.4619 - 1.961 0.599 - 257.8 1 2 0 0.0025 17 0 0 0 3.78E+06 1.41E+06 - - - 5.1201 0.9998 221125_WJC_METTL3_EV_vs_WT_F08.08071.08071.2 0.00446 18-Aug R.K[136.11]PSYAEIC[160.03]QR[166.11].T "sp|Q92615|LAR4B_HUMAN,tr|A0A087X183|A0A087X183_HUMAN,tr|H0Y4V9|H0Y4V9_HUMAN" 3 1268.6302 2.42 113210 8071 2 1268.630981 635.3224 La-related protein 4B OS=Homo sapiens OX=9606 GN=LARP4B PE=1 SV=3 8.2 1819.9 - 112296 - - - 0.5943 - 1.95 0.454 - 216.1 1 2 0 0.0008 10 0 0 0 5.98E+06 2.47E+06 - - - 4.2581 0.9999 221125_WJC_METTL3_EV_vs_WT_F08.08073.08073.3 0.000178 Dec-60 K.ELHNTPYGTASEPSEK.A sp|Q9NXV2|KCTD5_HUMAN 1 1758.8061 4.67 113211 8073 3 1758.807184 587.276 BTB\POZ domain-containing protein KCTD5 OS=Homo sapiens OX=9606 GN=KCTD5 PE=1 SV=1 4.75 1820.1 - 7.16E+06 - - - 0.6402 - 2.064 0.443 - 126.6 1 2 0 0.0011 16 0 0 0 1.44E+10 3.08E+09 - - - 5.338 0.9999 221125_WJC_METTL3_EV_vs_WT_F08.08075.08075.3 2.43E-05 Oct-44 K.VNWATTPSSQK[136.11]K[136.11].D "sp|Q01085|TIAR_HUMAN,sp|P31483|TIA1_HUMAN,tr|F8W8I6|F8W8I6_HUMAN,tr|C9JTN7|C9JTN7_HUMAN,tr|E7ETC0|E7ETC0_HUMAN,tr|H7BY49|H7BY49_HUMAN,tr|A6NKZ9|A6NKZ9_HUMAN,tr|E5RG67|E5RG67_HUMAN,tr|E7ETJ9|E7ETJ9_HUMAN,tr|E5RGV5|E5RGV5_HUMAN" 10 1361.7274 1.46 113212 8075 3 1361.728149 454.9164 Nucleolysin TIAR OS=Homo sapiens OX=9606 GN=TIAL1 PE=1 SV=1 10 1820.3 - 2.63E+06 - - - 0.5398 - 2.1 0.458 - 129.3 1 2 0 0.0007 12 0 0 0 1.16E+08 7.99E+07 - - - 5.7026 0.9908 221125_WJC_METTL3_EV_vs_WT_F08.08076.08076.2 0.000187 18-Nov Q.YEQLAEQNRK.D "sp|P13645|K1C10_HUMAN,tr|A0A1B0GVI3|A0A1B0GVI3_HUMAN" 2 1277.6364 999 113213 8076 2 1277.636477 639.8255 "Keratin, type I cytoskeletal 10 OS=Homo sapiens OX=9606 GN=KRT10 PE=1 SV=6" 6.14 1820.5 - 1.41E+06 - - - 0.0493 - 2.066 0.459 - 559.4 1 1 0 0.0001 10 0 0 0 4.44E+08 0.00E+00 - - - 4.4566 0.9788 221125_WJC_METTL3_EV_vs_WT_F08.08078.08078.3 0.0334 Nov-56 R.MFGGPGTASR[166.11]PSSSR[166.11].S "sp|P08670|VIME_HUMAN,tr|B0YJC4|B0YJC4_HUMAN,tr|A0A1B0GVG8|A0A1B0GVG8_HUMAN,tr|A0A1B0GTT5|A0A1B0GTT5_HUMAN" 4 1513.7211 0.99 113215 8078 3 1513.719231 505.581 Vimentin OS=Homo sapiens OX=9606 GN=VIM PE=1 SV=4 12 1820.6 - 2.58E+06 - - - -1.2017 - 1.486 0.165 - 117.7 1 2 0 -0.0018 15 0 0 0 2.26E+08 2.29E+08 - - - 1.4126 0.9987 221125_WJC_METTL3_EV_vs_WT_F08.08080.08080.2 0.000157 13/20 R.NTKQEIAEINR.M "sp|P48668|K2C6C_HUMAN,sp|P04259|K2C6B_HUMAN,sp|P02538|K2C6A_HUMAN" 3 1314.6892 999 113217 8080 2 1314.687905 658.3519 "Keratin, type II cytoskeletal 6C OS=Homo sapiens OX=9606 GN=KRT6C PE=1 SV=3" 6.14 1820.8 - 1.06E+06 - - - -0.9683 - 2.482 0.506 - 659.4 1 2 1 -0.0013 11 0 0 0 5.98E+08 0.00E+00 - - - 5.2372 1 221125_WJC_METTL3_EV_vs_WT_F08.08083.08083.3 0.00086 14/32 R.R[166.11]PDLDEIHR[166.11].E "sp|O00488|ZN593_HUMAN,tr|A9J4F5|A9J4F5_HUMAN" 2 1169.6056 0.27 113220 8083 3 1169.605006 390.8758 Zinc finger protein 593 OS=Homo sapiens OX=9606 GN=ZNF593 PE=1 SV=2 5.38 1821.1 - 447258 - - - -0.5164 - 2.694 0.409 - 385.6 1 2 0 -0.0006 9 0 0 0 3.61E+07 1.33E+08 - - - 6.0865 0.9552 221125_WJC_METTL3_EV_vs_WT_F08.08085.08085.2 0.000136 20-Dec T.GYVVERPSTTK.D "sp|Q9NYF8|BCLF1_HUMAN,tr|E9PKI6|E9PKI6_HUMAN,tr|A0A1W2PQ43|A0A1W2PQ43_HUMAN,tr|E9PK91|E9PK91_HUMAN,tr|E9PK09|E9PK09_HUMAN,tr|E9PQN2|E9PQN2_HUMAN" 6 1235.651 3.05 113222 8085 2 1235.655567 618.8328 Bcl-2-associated transcription factor 1 OS=Homo sapiens OX=9606 GN=BCLAF1 PE=1 SV=2 8.59 1821.4 - 342799 - - - 3.6952 - 2.269 0.531 - 437.4 1 1 0 0.0046 11 0 0 0 1.00E+08 3.29E+07 - - - 5.178 0.9618 221125_WJC_METTL3_EV_vs_WT_F08.08086.08086.2 0.0407 16-Oct Y.EQLAEQNRK.D "sp|P13645|K1C10_HUMAN,tr|A0A1B0GVI3|A0A1B0GVI3_HUMAN" 2 1114.5731 6.65 113223 8086 2 1114.574318 558.2938 "Keratin, type I cytoskeletal 10 OS=Homo sapiens OX=9606 GN=KRT10 PE=1 SV=6" 6.24 1821.5 - 210567 - - - 1.1063 - 1.894 0.296 - 522.1 1 1 0 0.0012 9 0 0 0 7.46E+07 1.12E+07 - - - 3.0746 0.9992 221125_WJC_METTL3_EV_vs_WT_F08.08091.08091.3 0.000848 Nov-44 K.VNWATTPSSQKK.D "sp|Q01085|TIAR_HUMAN,sp|P31483|TIA1_HUMAN,tr|F8W8I6|F8W8I6_HUMAN,tr|C9JTN7|C9JTN7_HUMAN,tr|E7ETC0|E7ETC0_HUMAN,tr|H7BY49|H7BY49_HUMAN,tr|A6NKZ9|A6NKZ9_HUMAN,tr|E5RG67|E5RG67_HUMAN,tr|E7ETJ9|E7ETJ9_HUMAN,tr|E5RGV5|E5RGV5_HUMAN" 10 1345.699 1.46 113226 8091 3 1345.695636 449.5736 Nucleolysin TIAR OS=Homo sapiens OX=9606 GN=TIAL1 PE=1 SV=1 10 1822 - 3.68E+06 - - - -2.5102 - 2.199 0.312 - 212.4 1 2 0 -0.0034 12 0 0 0 1.16E+08 7.92E+07 - - - 4.2018 0.9911 221125_WJC_METTL3_EV_vs_WT_F08.08094.08094.2 4.91E-08 28-Oct F.YGQTLGQAQAHSQEQ.- sp|Q96I24|FUBP3_HUMAN 1 1644.7492 - 113229 8094 2 1644.747089 823.3819 Far upstream element-binding protein 3 OS=Homo sapiens OX=9606 GN=FUBP3 PE=1 SV=2 5.24 1822.3 - 230825 - - - -1.2908 - 2.216 0.551 - 269.5 1 1 0 -0.0021 15 0 0 0 - - - - - 5.0663 0.9999 221125_WJC_METTL3_EV_vs_WT_F08.08099.08099.3 3.99E-08 14/52 K.YTAQVDAEEKEDVK.S sp|O75947|ATP5H_HUMAN 1 1623.7628 2.31 113232 8099 3 1623.760346 542.2615 "ATP synthase subunit d, mitochondrial OS=Homo sapiens OX=9606 GN=ATP5PD PE=1 SV=3" 4.18 1822.9 - 732183 - - - -1.5088 - 2.576 0.52 - 176.6 1 2 1 -0.0025 14 0 0 0 1.54E+07 6.69E+06 - - - 6.8515 1 221125_WJC_METTL3_EV_vs_WT_F08.08100.08100.2 6.17E-07 20-Dec T.GYVVER[166.11]PSTTK[136.11].D "sp|Q9NYF8|BCLF1_HUMAN,tr|E9PKI6|E9PKI6_HUMAN,tr|A0A1W2PQ43|A0A1W2PQ43_HUMAN,tr|E9PK91|E9PK91_HUMAN,tr|E9PK09|E9PK09_HUMAN,tr|E9PQN2|E9PQN2_HUMAN" 6 1253.6735 3.05 113233 8100 2 1253.67221 627.844 Bcl-2-associated transcription factor 1 OS=Homo sapiens OX=9606 GN=BCLAF1 PE=1 SV=2 8.59 1823.1 - 330313 - - - -1.0058 - 2.419 0.587 - 488.6 1 1 0 -0.0013 11 0 0 0 1.00E+08 3.29E+07 - - - 5.7659 0.9992 221125_WJC_METTL3_EV_vs_WT_F08.08106.08106.3 0.00969 Dec-36 K.K[136.11]FPHLAEAQK[136.11].S sp|Q9HD33|RM47_HUMAN 1 1183.6684 1.25 113237 8106 3 1183.664564 395.5634 "39S ribosomal protein L47, mitochondrial OS=Homo sapiens OX=9606 GN=MRPL47 PE=1 SV=2" 8.6 1823.8 - 612894 - - - -3.2771 - 2.242 0.343 - 185.8 1 2 0 -0.0039 10 0 0 0 1.21E+07 9.68E+06 - - - 4.7209 0.9998 221125_WJC_METTL3_EV_vs_WT_F08.08110.08110.3 0.0013 14/36 R.K[136.11]PSYAEIC[160.03]QR[166.11].T "sp|Q92615|LAR4B_HUMAN,tr|A0A087X183|A0A087X183_HUMAN,tr|H0Y4V9|H0Y4V9_HUMAN" 3 1268.6302 1.93 113239 8110 3 1268.626942 423.884 La-related protein 4B OS=Homo sapiens OX=9606 GN=LARP4B PE=1 SV=3 8.2 1824.4 - 1.85E+06 - - - -2.5894 - 2.48 0.41 - 457.5 1 2 0 -0.0033 10 0 0 0 8.91E+07 4.60E+07 - - - 5.7627 0.992 221125_WJC_METTL3_EV_vs_WT_F08.08121.08121.2 0.000117 20-Nov S.QYEQLAEQNRK.D "sp|P13645|K1C10_HUMAN,tr|A0A1B0GVI3|A0A1B0GVI3_HUMAN" 2 1405.695 3.31 113247 8121 2 1405.693516 703.8548 "Keratin, type I cytoskeletal 10 OS=Homo sapiens OX=9606 GN=KRT10 PE=1 SV=6" 6.14 1825.6 - 1.01E+06 - - - -1.05 - 2.167 0.529 - 460 1 1 0 -0.0015 11 0 0 0 2.42E+07 7.32E+06 - - - 5.0398 0.9998 221125_WJC_METTL3_EV_vs_WT_F08.08123.08123.3 0.000676 Dec-32 R.EYTINIHKR.L "sp|P62899|RL31_HUMAN,tr|B7Z4C8|B7Z4C8_HUMAN,tr|B7Z4E3|B7Z4E3_HUMAN,tr|B8ZZK4|B8ZZK4_HUMAN,tr|H7C2W9|H7C2W9_HUMAN,tr|C9JU56|C9JU56_HUMAN" 6 1172.6302 0.84 113249 8123 3 1172.628046 391.884 60S ribosomal protein L31 OS=Homo sapiens OX=9606 GN=RPL31 PE=1 SV=1 8.69 1825.9 - 1.15E+06 - - - -1.842 - 2.039 0.405 - 291.8 1 2 0 -0.0022 9 0 0 0 1.08E+08 1.28E+08 - - - 5.202 1 221125_WJC_METTL3_EV_vs_WT_F08.08139.08139.3 0.000239 17/56 R.EAVLSNQRPGYGDNK.L sp|P17482|HXB9_HUMAN 1 1646.8012 1.57 113256 8139 3 1646.799682 549.941 Homeobox protein Hox-B9 OS=Homo sapiens OX=9606 GN=HOXB9 PE=1 SV=2 6.17 1827.8 - 2.66E+06 - - - -0.9509 - 2.702 0.473 - 393.3 1 2 0 -0.0016 15 0 0 0 8.49E+07 5.42E+07 - - - 6.4067 1 221125_WJC_METTL3_EV_vs_WT_F08.08140.08140.3 9.23E-09 16/56 K.ITPAHDQNDYEVGQR.H "sp|P26640|SYVC_HUMAN,tr|A0A140T936|A0A140T936_HUMAN" 2 1741.802 0.61 113257 8140 3 1741.804644 581.6079 Valine--tRNA ligase OS=Homo sapiens OX=9606 GN=VARS1 PE=1 SV=4 4.54 1827.9 - 1.57E+06 - - - 1.5317 - 3.299 0.675 - 385.7 1 2 0 0.0027 15 0 0 0 4.09E+07 6.68E+07 - - - 9.1794 0.9965 221125_WJC_METTL3_EV_vs_WT_F08.08150.08150.3 0.00637 13/44 R.GK[136.11]GEGDLSQLSK[136.11].Q sp|Q9P013|CWC15_HUMAN 1 1233.6536 0.93 113263 8150 3 1233.651172 412.2251 Spliceosome-associated protein CWC15 homolog OS=Homo sapiens OX=9606 GN=CWC15 PE=1 SV=2 6.07 1829.2 - 1.14E+06 - - - -1.9527 - 1.736 0.347 - 192 1 2 1 -0.0024 12 0 0 0 3.94E+07 4.26E+07 - - - 3.9369 0.9984 221125_WJC_METTL3_EV_vs_WT_F08.08151.08151.2 0.000861 15/22 R.GKGEGDLSQLSK.Q sp|Q9P013|CWC15_HUMAN 1 1217.6252 0.51 113264 8151 2 1217.623155 609.8199 Spliceosome-associated protein CWC15 homolog OS=Homo sapiens OX=9606 GN=CWC15 PE=1 SV=2 6.07 1829.3 - 1.06E+06 - - - -1.6639 - 2.778 0.528 - 492.4 1 2 1 -0.002 12 0 0 0 4.21E+07 8.28E+07 - - - 5.6285 0.9994 221125_WJC_METTL3_EV_vs_WT_F08.08152.08152.3 0.0106 Nov-32 R.IQVWHEEHR[166.11].G sp|P26038|MOES_HUMAN 1 1242.6133 0.69 113265 8152 3 1242.610724 415.2117 Moesin OS=Homo sapiens OX=9606 GN=MSN PE=1 SV=3 6 1829.5 - 943244 - - - -2.0924 - 1.965 0.331 - 184.5 1 2 0 -0.0026 9 0 0 0 1.56E+07 2.26E+07 - - - 4.2654 0.9999 221125_WJC_METTL3_EV_vs_WT_F08.08156.08156.3 2.52E-05 Nov-44 K.K[136.11]YEEIDNAPEER[166.11].A sp|P49411|EFTU_HUMAN 1 1509.7066 1.42 113267 8156 3 1509.702636 504.2428 "Elongation factor Tu, mitochondrial OS=Homo sapiens OX=9606 GN=TUFM PE=1 SV=2" 4.25 1830 - 6.43E+06 - - - -2.6402 - 2.596 0.486 - 171.5 1 2 0 -0.004 12 0 0 0 3.23E+08 2.28E+08 - - - 6.6016 0.9999 221125_WJC_METTL3_EV_vs_WT_F08.08160.08160.3 3.85E-06 15/44 K.K[136.11]LDAQVQELHAK[136.11].V sp|P35580|MYH10_HUMAN 1 1394.7853 0.98 113271 8160 3 1394.78164 465.9357 Myosin-10 OS=Homo sapiens OX=9606 GN=MYH10 PE=1 SV=3 6.75 1830.3 - 650812 - - - -2.5982 - 2.626 0.468 - 393.6 1 2 0 -0.0036 12 0 0 0 1.19E+08 1.21E+08 - - - 6.4328 0.9995 221125_WJC_METTL3_EV_vs_WT_F08.08164.08164.3 0.00334 Oct-36 R.KPSYAEIC[160.03]QR.T "sp|Q92615|LAR4B_HUMAN,tr|A0A087X183|A0A087X183_HUMAN,tr|H0Y4V9|H0Y4V9_HUMAN" 3 1250.6078 1.92 113273 8164 3 1250.607182 417.8765 La-related protein 4B OS=Homo sapiens OX=9606 GN=LARP4B PE=1 SV=3 8.2 1830.8 - 1.15E+06 - - - -0.4598 - 1.855 0.318 - 222.2 1 2 0 -0.0006 10 0 0 0 1.07E+08 5.58E+07 - - - 3.8897 1 221125_WJC_METTL3_EV_vs_WT_F08.08165.08165.3 2.96E-06 17/52 R.WEQQVSAADGKPGR.Q "sp|Q6W2J9|BCOR_HUMAN,tr|H7BZ37|H7BZ37_HUMAN,tr|H7C2V9|H7C2V9_HUMAN,tr|H7BYY2|H7BYY2_HUMAN,tr|H7C231|H7C231_HUMAN" 5 1527.743 2.28 113274 8165 3 1527.739894 510.2549 BCL-6 corepressor OS=Homo sapiens OX=9606 GN=BCOR PE=1 SV=1 6.07 1830.9 - 3.37E+06 - - - -2.0357 - 2.883 0.547 - 512 1 2 0 -0.0031 14 0 0 0 1.15E+08 5.05E+07 - - - 7.4515 1 221125_WJC_METTL3_EV_vs_WT_F08.08166.08166.3 1.39E-05 19/60 K.LLETTDRPDGHQNNLR.S "sp|Q14974|IMB1_HUMAN,tr|J3KTM9|J3KTM9_HUMAN" 2 1877.9344 1.44 113275 8166 3 1877.933993 626.9854 Importin subunit beta-1 OS=Homo sapiens OX=9606 GN=KPNB1 PE=1 SV=2 5.38 1831 - 1.57E+06 - - - -0.2098 - 2.375 0.488 - 431.9 1 2 0 -0.0004 16 0 0 0 1.29E+08 8.96E+07 - - - 6.2001 1 221125_WJC_METTL3_EV_vs_WT_F08.08169.08169.2 2.42E-07 15/22 E.TGYVVERPSTTK.D "sp|Q9NYF8|BCLF1_HUMAN,tr|E9PKI6|E9PKI6_HUMAN,tr|A0A1W2PQ43|A0A1W2PQ43_HUMAN,tr|E9PK91|E9PK91_HUMAN,tr|E9PK09|E9PK09_HUMAN,tr|E9PQN2|E9PQN2_HUMAN" 6 1336.6987 3.56 113278 8169 2 1336.697405 669.3566 Bcl-2-associated transcription factor 1 OS=Homo sapiens OX=9606 GN=BCLAF1 PE=1 SV=2 8.26 1831.4 - 520090 - - - -0.9538 - 2.678 0.628 - 581.1 1 1 0 -0.0013 12 0 0 0 2.70E+07 7.57E+06 - - - 6.2709 0.9997 221125_WJC_METTL3_EV_vs_WT_F08.08174.08174.3 0.000127 14/44 K.KLDAQVQELHAK.V sp|P35580|MYH10_HUMAN 1 1378.7569 0.99 113281 8174 3 1378.753795 460.5929 Myosin-10 OS=Homo sapiens OX=9606 GN=MYH10 PE=1 SV=3 6.75 1832 - 1.63E+06 - - - -2.2259 - 2.416 0.343 - 359.3 1 2 0 -0.0031 12 0 0 0 1.19E+08 1.21E+08 - - - 4.8083 0.9998 221125_WJC_METTL3_EV_vs_WT_F08.08177.08177.3 0.000246 Nov-36 K.FHNELNAHIK.L sp|P12270|TPR_HUMAN 1 1221.6255 2.69 113284 8177 3 1221.622975 408.2158 Nucleoprotein TPR OS=Homo sapiens OX=9606 GN=TPR PE=1 SV=3 6.92 1832.2 - 1.01E+06 - - - -2.0301 - 1.962 0.415 - 149.5 1 2 0 -0.0025 10 0 0 0 6.31E+07 2.35E+07 - - - 5.1344 1 221125_WJC_METTL3_EV_vs_WT_F08.08182.08182.3 5.81E-11 20/60 K.LLETTDR[166.11]PDGHQNNLR[166.11].S "sp|Q14974|IMB1_HUMAN,tr|J3KTM9|J3KTM9_HUMAN" 2 1897.9509 1.44 113286 8182 3 1897.948271 633.6576 Importin subunit beta-1 OS=Homo sapiens OX=9606 GN=KPNB1 PE=1 SV=2 5.38 1833 - 2.33E+06 - - - -1.3994 - 3.424 0.501 - 482.8 1 2 0 -0.0027 16 0 0 0 1.29E+08 8.96E+07 - - - 7.283 0.9933 221125_WJC_METTL3_EV_vs_WT_F08.08185.08185.3 0.483 Sep-40 R.ESQSVEEALK[136.11]K[136.11].L sp|P49915|GUAA_HUMAN 1 1262.6689 1.13 113289 8185 3 1262.666243 421.8969 GMP synthase [glutamine-hydrolyzing] OS=Homo sapiens OX=9606 GN=GMPS PE=1 SV=1 4.79 1833.3 - 843293 - - - -2.1011 - 1.632 0.228 - 96.1 1 2 0 -0.0027 11 0 0 0 2.58E+07 2.28E+07 - - - 2.4727 0.9423 221125_WJC_METTL3_EV_vs_WT_F08.08193.08193.3 0.51 Nov-40 R.ESQSVEEALKK.L sp|P49915|GUAA_HUMAN 1 1246.6405 1.12 113295 8193 3 1246.637526 416.5541 GMP synthase [glutamine-hydrolyzing] OS=Homo sapiens OX=9606 GN=GMPS PE=1 SV=1 4.79 1834.4 - 891843 - - - -2.3824 - 1.515 0.138 - 159.1 1 2 0 -0.003 11 0 0 0 2.65E+07 2.37E+07 - - - 1.2579 0.8325 221125_WJC_METTL3_EV_vs_WT_F08.08194.08194.3 0.0228 15/52 L.ETTDR[166.11]PDGHQNNLR[166.11].S "sp|Q14974|IMB1_HUMAN,tr|J3KTM9|J3KTM9_HUMAN" 2 1671.7828 1.25 113296 8194 3 1671.779953 558.2682 Importin subunit beta-1 OS=Homo sapiens OX=9606 GN=KPNB1 PE=1 SV=2 5.38 1834.5 - 392967 - - - -1.7024 - 2.029 0.243 - 254.5 1 1 0 -0.0028 14 0 0 0 1.48E+07 1.18E+07 - - - 3.1287 0.9879 221125_WJC_METTL3_EV_vs_WT_F08.08195.08195.3 0.13 Jul-48 K.VEEC[160.03]FHGENQYSK.S "sp|Q6N021|TET2_HUMAN,tr|E7EQS8|E7EQS8_HUMAN,tr|E7EPB1|E7EPB1_HUMAN" 3 1625.678 1.62 113297 8195 3 1625.676793 542.9 Methylcytosine dioxygenase TET2 OS=Homo sapiens OX=9606 GN=TET2 PE=1 SV=3 4.75 1834.6 - 356194 - - - -0.7554 - 1.08 0.264 - 34.5 1 2 0 -0.0012 13 0 0 0 7.45E+06 4.60E+06 - - - 1.6917 0.9998 221125_WJC_METTL3_EV_vs_WT_F08.08198.08198.2 0.000997 20-Sep R.ADTQTYQPYNK.D sp|P84090|ERH_HUMAN 1 1327.6044 2.36 113298 8198 2 1327.604894 664.8095 Enhancer of rudimentary homolog OS=Homo sapiens OX=9606 GN=ERH PE=1 SV=1 5.88 1835 - 996001 - - - 0.3382 - 1.777 0.441 - 249.4 1 2 0 0.0004 11 0 0 0 8.15E+07 3.45E+07 - - - 3.8534 1 221125_WJC_METTL3_EV_vs_WT_F08.08202.08202.2 0.00153 17/26 K.K[136.11]GPGEVAGTVTGQK[136.11].R "sp|Q86U44|MTA70_HUMAN,tr|F5H6D8|F5H6D8_HUMAN,tr|H0YFV6|H0YFV6_HUMAN,tr|B4DTN4|B4DTN4_HUMAN" 4 1343.738 0.001 113300 8202 2 1343.736433 672.8763 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 8.59 1835.4 - 505430 - - - -1.1505 - 3.388 0.588 - 668.9 1 2 0 -0.0015 14 0 0 0 0.00E+00 2.10E+07 - - - 6.4456 0.9985 221125_WJC_METTL3_EV_vs_WT_F08.08205.08205.2 0.0103 20-Sep R.ADTQTYQPYNK[136.11].D sp|P84090|ERH_HUMAN 1 1335.6186 2.36 113301 8205 2 1335.616533 668.8166 Enhancer of rudimentary homolog OS=Homo sapiens OX=9606 GN=ERH PE=1 SV=1 5.88 1835.8 - 693670 - - - -1.5813 - 1.193 0.397 - 210.6 1 2 0 -0.0021 11 0 0 0 8.15E+07 3.45E+07 - - - 2.45 0.9967 221125_WJC_METTL3_EV_vs_WT_F08.08206.08206.3 1.35E-05 14/56 L.LETTDRPDGHQNNLR.S "sp|Q14974|IMB1_HUMAN,tr|J3KTM9|J3KTM9_HUMAN" 2 1764.8503 1.97 113302 8206 3 1764.852251 589.2907 Importin subunit beta-1 OS=Homo sapiens OX=9606 GN=KPNB1 PE=1 SV=2 5.38 1836 - 674778 - - - 1.0924 - 2.59 0.504 - 263.4 1 1 0 0.0019 15 0 0 0 1.15E+07 5.85E+06 - - - 6.6418 1 221125_WJC_METTL3_EV_vs_WT_F08.08209.08209.2 4.22E-06 24-Dec K.QSSVTQVTEQSPK[136.11].V "sp|Q14966|ZN638_HUMAN,tr|C9JWN0|C9JWN0_HUMAN" 2 1425.7191 1.02 113303 8209 2 1425.716819 713.8668 Zinc finger protein 638 OS=Homo sapiens OX=9606 GN=ZNF638 PE=1 SV=2 6 1836.4 - 713468 - - - -1.5915 - 2.808 0.591 - 619.5 1 2 0 -0.0023 13 0 0 0 6.54E+07 6.42E+07 - - - 6.0553 1 221125_WJC_METTL3_EV_vs_WT_F08.08213.08213.3 7.92E-05 15/52 K.K[136.11]GPGEVAGTVTGQK[136.11].R "sp|Q86U44|MTA70_HUMAN,tr|F5H6D8|F5H6D8_HUMAN,tr|H0YFV6|H0YFV6_HUMAN,tr|B4DTN4|B4DTN4_HUMAN" 4 1343.738 0.32 113305 8213 3 1343.736554 448.9199 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 8.59 1836.9 - 2.05E+06 - - - -1.0605 - 2.906 0.555 - 385.5 1 2 0 -0.0014 14 0 0 0 3.05E+07 9.68E+07 - - - 7.5623 0.9972 221125_WJC_METTL3_EV_vs_WT_F08.08215.08215.4 0.0278 Nov-72 R.YDERPGPSPLPHR.D sp|P08621|RU17_HUMAN 1 1519.7532 0.81 113307 8215 4 1519.750149 380.9456 U1 small nuclear ribonucleoprotein 70 kDa OS=Homo sapiens OX=9606 GN=SNRNP70 PE=1 SV=2 6.75 1837.1 - 1.06E+06 - - - -1.9911 - 1.945 0.265 - 70.1 1 2 0 -0.003 13 0 0 0 4.78E+07 5.91E+07 - - - 1.7784 1 221125_WJC_METTL3_EV_vs_WT_F08.08219.08219.2 5.67E-06 13/24 K.QSSVTQVTEQSPK.V "sp|Q14966|ZN638_HUMAN,tr|C9JWN0|C9JWN0_HUMAN" 2 1417.7049 1.01 113308 8219 2 1417.704339 709.8597 Zinc finger protein 638 OS=Homo sapiens OX=9606 GN=ZNF638 PE=1 SV=2 6 1837.7 - 1.24E+06 - - - -0.3872 - 2.931 0.593 - 859.6 1 2 0 -0.0005 13 0 0 0 3.73E+07 3.69E+07 - - - 6.1806 0.9931 221125_WJC_METTL3_EV_vs_WT_F08.08223.08223.2 0.0012 22-Jul R.YSGGNYR[166.11]DNYDN.- sp|P98179|RBM3_HUMAN 1 1446.5676 0.97 113310 8223 2 1446.565973 724.2911 RNA-binding protein 3 OS=Homo sapiens OX=9606 GN=RBM3 PE=1 SV=1 4.21 1838.2 - 413587 - - - -1.0943 - 1.216 0.47 - 66 1 2 1 -0.0016 12 0 0 0 2.42E+07 2.49E+07 - - - 3.0265 0.9966 221125_WJC_METTL3_EV_vs_WT_F08.08229.08229.2 0.000242 22-Aug R.YSGGNYRDNYDN.- sp|P98179|RBM3_HUMAN 1 1436.5593 0.97 113313 8229 2 1436.556803 719.2869 RNA-binding protein 3 OS=Homo sapiens OX=9606 GN=RBM3 PE=1 SV=1 4.21 1838.9 - 665711 - - - -1.7284 - 1.36 0.604 - 92.5 1 2 1 -0.0025 12 0 0 0 2.42E+07 2.49E+07 - - - 4.3104 0.9999 221125_WJC_METTL3_EV_vs_WT_F08.08234.08234.3 1.35E-05 Sep-48 R.VNLC[160.03]EC[160.03]THPTQC[160.03]R.A "sp|Q14574|DSC3_HUMAN,tr|J3QRL9|J3QRL9_HUMAN" 2 1673.7072 13.92 113316 8234 3 1673.71047 558.9097 Desmocollin-3 OS=Homo sapiens OX=9606 GN=DSC3 PE=1 SV=3 6.7 1839.5 - 347848 - - - 1.9358 - 1.966 0.524 - 94.8 1 2 0 0.0032 13 0 0 0 9.67E+06 6.95E+05 - - - 6.214 0.9999 221125_WJC_METTL3_EV_vs_WT_F08.08235.08235.3 8.52E-07 17/44 K.MK[136.11]ETAEAYLGK[136.11]K[136.11].V "sp|P11021|BIP_HUMAN,tr|A0A7P0TB36|A0A7P0TB36_HUMAN,tr|A0A7P0TAI0|A0A7P0TAI0_HUMAN" 3 1391.7545 0.49 113317 8235 3 1391.755072 464.9254 Endoplasmic reticulum chaperone BiP OS=Homo sapiens OX=9606 GN=HSPA5 PE=1 SV=2 8.19 1839.5 - 2.68E+06 - - - 0.4203 - 3.39 0.461 - 318.6 1 2 1 0.0006 12 0 0 0 4.67E+07 9.55E+07 - - - 7.0635 1 221125_WJC_METTL3_EV_vs_WT_F08.08236.08236.3 3.26E-06 Oct-40 K.C[160.03]NIQYPATEHR.D sp|Q53EZ4|CEP55_HUMAN 1 1387.6303 0.65 113318 8236 3 1387.628138 463.5507 Centrosomal protein of 55 kDa OS=Homo sapiens OX=9606 GN=CEP55 PE=1 SV=3 6.74 1839.6 - 947382 - - - -1.5458 - 1.984 0.535 - 147.3 1 2 0 -0.0021 11 0 0 0 2.40E+07 3.69E+07 - - - 6.4504 1 221125_WJC_METTL3_EV_vs_WT_F08.08237.08237.3 4.84E-09 17/60 R.LLSDATVEK[136.11]DESHAGK[136.11].V sp|Q14320|FA50A_HUMAN 1 1714.8708 0.75 113319 8237 3 1714.866477 572.6309 Protein FAM50A OS=Homo sapiens OX=9606 GN=FAM50A PE=1 SV=2 4.75 1839.8 - 452318 - - - -2.5465 - 3.08 0.638 - 330.5 1 2 1 -0.0044 16 0 0 0 6.10E+06 8.13E+06 - - - 8.5383 0.9999 221125_WJC_METTL3_EV_vs_WT_F08.08241.08241.3 0.00157 Dec-48 K.ETGYVVERPSTTK.D "sp|Q9NYF8|BCLF1_HUMAN,tr|E9PKI6|E9PKI6_HUMAN,tr|A0A1W2PQ43|A0A1W2PQ43_HUMAN,tr|E9PK91|E9PK91_HUMAN,tr|E9PK09|E9PK09_HUMAN,tr|E9PQN2|E9PQN2_HUMAN" 6 1465.7413 2.36 113322 8241 3 1465.741087 489.5877 Bcl-2-associated transcription factor 1 OS=Homo sapiens OX=9606 GN=BCLAF1 PE=1 SV=2 6.24 1840.2 - 1.59E+07 - - - -0.1269 - 2.544 0.374 - 142.6 1 2 0 -0.0002 13 0 0 0 2.25E+09 9.55E+08 - - - 5.2413 1 221125_WJC_METTL3_EV_vs_WT_F08.08246.08246.3 1.12E-05 13/56 R.AAHSEGNTTAGLDMR[166.11].E sp|P78371|TCPB_HUMAN 1 1539.6975 0.45 113325 8246 3 1539.697771 514.2398 T-complex protein 1 subunit beta OS=Homo sapiens OX=9606 GN=CCT2 PE=1 SV=4 5.32 1840.8 - 1.35E+06 - - - 0.1604 - 2.135 0.51 - 187.9 1 2 0 0.0002 15 0 0 0 5.01E+08 1.11E+09 - - - 6.205 1 221125_WJC_METTL3_EV_vs_WT_F08.08250.08250.3 0.000247 15/36 K.R[166.11]LEIEHSVPK[136.11].K sp|Q9NZI8|IF2B1_HUMAN 1 1224.6945 1.47 113328 8250 3 1224.694398 409.2388 Insulin-like growth factor 2 mRNA-binding protein 1 OS=Homo sapiens OX=9606 GN=IGF2BP1 PE=1 SV=2 6.76 1841.3 - 1.46E+07 - - - -0.1168 - 2.797 0.406 - 465.8 1 2 0 -0.0001 10 0 0 0 9.83E+08 6.69E+08 - - - 6.0703 0.9999 221125_WJC_METTL3_EV_vs_WT_F08.08251.08251.3 2.13E-05 13/48 K.ETGYVVER[166.11]PSTTK[136.11].D "sp|Q9NYF8|BCLF1_HUMAN,tr|E9PKI6|E9PKI6_HUMAN,tr|A0A1W2PQ43|A0A1W2PQ43_HUMAN,tr|E9PK91|E9PK91_HUMAN,tr|E9PK09|E9PK09_HUMAN,tr|E9PQN2|E9PQN2_HUMAN" 6 1483.7637 2.12 113329 8251 3 1483.764177 495.5952 Bcl-2-associated transcription factor 1 OS=Homo sapiens OX=9606 GN=BCLAF1 PE=1 SV=2 6.24 1841.3 - 2.87E+06 - - - 0.2925 - 2.267 0.45 - 207.4 1 2 0 0.0004 13 0 0 0 4.82E+09 2.27E+09 - - - 5.776 0.9999 221125_WJC_METTL3_EV_vs_WT_F08.08259.08259.3 0.00637 13/36 K.RLEIEHSVPK.K sp|Q9NZI8|IF2B1_HUMAN 1 1206.6721 1.47 113335 8259 3 1206.673247 403.2313 Insulin-like growth factor 2 mRNA-binding protein 1 OS=Homo sapiens OX=9606 GN=IGF2BP1 PE=1 SV=2 6.76 1842.4 - 2.31E+07 - - - 0.9746 - 2.168 0.405 - 242.3 1 2 0 0.0012 10 0 0 0 9.83E+08 6.69E+08 - - - 5.3149 1 221125_WJC_METTL3_EV_vs_WT_F08.08260.08260.3 2.10E-06 15/56 R.AAHSEGNTTAGLDMR.E sp|P78371|TCPB_HUMAN 1 1529.6893 0.45 113336 8260 3 1529.690747 510.9037 T-complex protein 1 subunit beta OS=Homo sapiens OX=9606 GN=CCT2 PE=1 SV=4 5.32 1842.5 - 1.94E+06 - - - 0.976 - 2.363 0.596 - 294.7 1 2 0 0.0015 15 0 0 0 5.01E+08 1.11E+09 - - - 7.4283 0.9998 221125_WJC_METTL3_EV_vs_WT_F08.08261.08261.4 2.57E-07 20/90 R.LLSDATVEK[136.11]DESHAGK[136.11].V sp|Q14320|FA50A_HUMAN 1 1714.8708 0.6 113337 8261 4 1714.872857 429.725 Protein FAM50A OS=Homo sapiens OX=9606 GN=FAM50A PE=1 SV=2 4.75 1842.6 - 1.44E+06 - - - 1.1738 - 2.954 0.485 - 298.3 1 2 1 0.002 16 0 0 0 1.43E+07 2.37E+07 - - - 3.8284 0.9974 221125_WJC_METTL3_EV_vs_WT_F08.08262.08262.3 0.0132 Oct-48 K.IQDKEGIPPDQQR.L "sp|P62979|RS27A_HUMAN,sp|P0CG48|UBC_HUMAN,sp|P0CG48|UBC_HUMAN,sp|P0CG48|UBC_HUMAN,sp|P0CG48|UBC_HUMAN,sp|P0CG48|UBC_HUMAN,sp|P0CG48|UBC_HUMAN,sp|P0CG48|UBC_HUMAN,sp|P0CG48|UBC_HUMAN,sp|P0CG48|UBC_HUMAN,sp|P0CG47|UBB_HUMAN,sp|P0CG47|UBB_HUMAN,sp|P0CG47|UBB_HUMAN,sp|P62987|RL40_HUMAN,tr|F5H388|F5H388_HUMAN,tr|F5H388|F5H388_HUMAN,tr|F5GYU3|F5GYU3_HUMAN,tr|F5GYU3|F5GYU3_HUMAN,tr|B4DV12|B4DV12_HUMAN,tr|B4DV12|B4DV12_HUMAN,tr|J3QSA3|J3QSA3_HUMAN,tr|Q5PY61|Q5PY61_HUMAN,tr|Q5PY61|Q5PY61_HUMAN,tr|Q5PY61|Q5PY61_HUMAN,tr|F5H2Z3|F5H2Z3_HUMAN,tr|F5H2Z3|F5H2Z3_HUMAN,tr|M0R2S1|M0R2S1_HUMAN,tr|J3QS39|J3QS39_HUMAN,tr|J3QTR3|J3QTR3_HUMAN,tr|Q96C32|Q96C32_HUMAN,tr|Q96C32|Q96C32_HUMAN,tr|Q96C32|Q96C32_HUMAN,tr|Q96C32|Q96C32_HUMAN,tr|M0R1V7|M0R1V7_HUMAN,tr|F5H747|F5H747_HUMAN,tr|F5H747|F5H747_HUMAN,tr|F5GXK7|F5GXK7_HUMAN,tr|F5GXK7|F5GXK7_HUMAN,tr|M0R1M6|M0R1M6_HUMAN,tr|F5H6Q2|F5H6Q2_HUMAN,tr|F5H6Q2|F5H6Q2_HUMAN,tr|F5GZ39|F5GZ39_HUMAN,tr|J3QKN0|J3QKN0_HUMAN,tr|J3QKN0|J3QKN0_HUMAN,tr|F5H265|F5H265_HUMAN,tr|F5H265|F5H265_HUMAN,tr|A0A2R8Y422|A0A2R8Y422_HUMAN" 47 1522.774 0.99 113338 8262 3 1522.775961 508.5986 Ubiquitin-40S ribosomal protein S27a OS=Homo sapiens OX=9606 GN=RPS27A PE=1 SV=2 4.56 1842.6 - 815548 - - - 1.3075 - 2.061 0.307 - 155.6 1 2 1 0.002 13 0 0 0 4.96E+07 4.99E+07 - - - 3.923 0.9999 221125_WJC_METTL3_EV_vs_WT_F08.08270.08270.3 0.00132 Nov-44 R.LHNTIVEINNHK[136.11].L "sp|Q9NTJ3|SMC4_HUMAN,tr|E9PD53|E9PD53_HUMAN" 2 1438.7772 0.42 113344 8270 3 1438.778772 480.5997 Structural maintenance of chromosomes protein 4 OS=Homo sapiens OX=9606 GN=SMC4 PE=1 SV=2 6.92 1843.7 - 1.32E+06 - - - 1.0843 - 2.177 0.441 - 193.1 1 2 0 0.0016 12 0 0 0 2.03E+07 4.86E+07 - - - 5.6126 0.9999 221125_WJC_METTL3_EV_vs_WT_F08.08271.08271.3 2.00E-05 Nov-44 R.LHNTIVEINNHK.L "sp|Q9NTJ3|SMC4_HUMAN,tr|E9PD53|E9PD53_HUMAN" 2 1430.763 0.4 113345 8271 3 1430.764664 477.9283 Structural maintenance of chromosomes protein 4 OS=Homo sapiens OX=9606 GN=SMC4 PE=1 SV=2 6.92 1843.7 - 863187 - - - 1.1546 - 2.324 0.46 - 178.9 1 2 0 0.0017 12 0 0 0 2.03E+07 5.06E+07 - - - 6.0056 0.9991 221125_WJC_METTL3_EV_vs_WT_F08.08272.08272.3 4.30E-05 14/44 K.K[136.11]ATVNLLGEEK[136.11]K[136.11].S sp|Q00765|REEP5_HUMAN 1 1352.809 1.08 113346 8272 3 1352.810829 451.9436 Receptor expression-enhancing protein 5 OS=Homo sapiens OX=9606 GN=REEP5 PE=1 SV=3 8.5 1843.8 - 914752 - - - 1.3771 - 2.477 0.231 - 259.7 1 2 0 0.0019 12 0 0 0 1.94E+07 1.79E+07 - - - 3.6291 0.996 221125_WJC_METTL3_EV_vs_WT_F08.08274.08274.3 0.0051 14/40 K.NILNK[136.11]PEVNQK[136.11].L "sp|P52732|KIF11_HUMAN,tr|A0A7I2YQY4|A0A7I2YQY4_HUMAN,tr|A0A7I2V3A9|A0A7I2V3A9_HUMAN,tr|A0A7I2V3V3|A0A7I2V3V3_HUMAN" 4 1311.7481 5.03 113348 8274 3 1311.753092 438.2567 Kinesin-like protein KIF11 OS=Homo sapiens OX=9606 GN=KIF11 PE=1 SV=2 8.59 1844 - 492436 - - - 3.7675 - 1.899 0.299 - 237.4 1 2 0 0.0049 11 0 0 0 1.49E+08 2.97E+07 - - - 3.6941 1 221125_WJC_METTL3_EV_vs_WT_F08.08275.08275.2 4.70E-09 14/28 R.AAHSEGNTTAGLDMR.E sp|P78371|TCPB_HUMAN 1 1529.6893 0.44 113349 8275 2 1529.691445 765.8519 T-complex protein 1 subunit beta OS=Homo sapiens OX=9606 GN=CCT2 PE=1 SV=4 5.32 1844.2 - 246236 - - - 1.4323 - 2.889 0.649 - 486 1 2 0 0.0022 15 0 0 0 2.42E+07 5.50E+07 - - - 6.4421 1 221125_WJC_METTL3_EV_vs_WT_F08.08278.08278.2 1.14E-09 16/28 R.AAHSEGNTTAGLDMR[166.11].E sp|P78371|TCPB_HUMAN 1 1539.6975 0.44 113350 8278 2 1539.700245 770.856 T-complex protein 1 subunit beta OS=Homo sapiens OX=9606 GN=CCT2 PE=1 SV=4 5.32 1844.6 - 912827 - - - 1.7672 - 3.118 0.726 - 545.3 1 2 0 0.0027 15 0 0 0 2.42E+07 5.50E+07 - - - 7.1982 0.9953 221125_WJC_METTL3_EV_vs_WT_F08.08279.08279.2 0.362 18-Jul K.R[166.11]LEIEHSVPK[136.11].K sp|Q9NZI8|IF2B1_HUMAN 1 1224.6945 1.69 113351 8279 2 1224.695208 613.3545 Insulin-like growth factor 2 mRNA-binding protein 1 OS=Homo sapiens OX=9606 GN=IGF2BP1 PE=1 SV=2 6.76 1844.7 - 829196 - - - 0.5446 - 1.464 0.15 - 131.1 1 2 0 0.0007 10 0 0 0 3.78E+07 2.24E+07 - - - 1.2127 0.9998 221125_WJC_METTL3_EV_vs_WT_F08.08280.08280.2 2.54E-07 28-Nov K.QQGASGEVYC[160.03]PSGEK[136.11].C sp|Q7Z5L9|I2BP2_HUMAN 1 1603.7028 1.73 113352 8280 2 1603.705775 802.8587 Interferon regulatory factor 2-binding protein 2 OS=Homo sapiens OX=9606 GN=IRF2BP2 PE=1 SV=2 4.53 1844.8 - 309550 - - - 1.8638 - 2.28 0.625 - 293.1 1 2 0 0.003 15 0 0 0 7.61E+07 4.39E+07 - - - 5.6826 0.9913 221125_WJC_METTL3_EV_vs_WT_F08.08284.08284.3 0.0242 Nov-44 K.MKETAEAYLGKK.V "sp|P11021|BIP_HUMAN,tr|A0A7P0TB36|A0A7P0TB36_HUMAN,tr|A0A7P0TAI0|A0A7P0TAI0_HUMAN" 3 1367.7119 0.49 113354 8284 3 1367.714019 456.9112 Endoplasmic reticulum chaperone BiP OS=Homo sapiens OX=9606 GN=HSPA5 PE=1 SV=2 8.19 1845.4 - 2.16E+06 - - - 1.5588 - 1.801 0.266 - 128.3 1 2 1 0.0021 12 0 0 0 4.67E+07 9.46E+07 - - - 3.1358 0.9998 221125_WJC_METTL3_EV_vs_WT_F08.08285.08285.3 0.000213 13/44 K.QEYVDYSESAKK.E sp|O60832|DKC1_HUMAN 1 1445.6674 1.06 113355 8285 3 1445.670081 482.8964 H\ACA ribonucleoprotein complex subunit DKC1 OS=Homo sapiens OX=9606 GN=DKC1 PE=1 SV=3 4.68 1845.4 - 799822 - - - 1.8275 - 1.659 0.441 - 129.6 1 2 0 0.0026 12 0 0 0 2.34E+07 2.22E+07 - - - 4.8591 1 221125_WJC_METTL3_EV_vs_WT_F08.08287.08287.3 3.72E-08 15/44 K.QEYVDYSESAK[136.11]K[136.11].E sp|O60832|DKC1_HUMAN 1 1461.6958 1.04 113357 8287 3 1461.69489 488.2392 H\ACA ribonucleoprotein complex subunit DKC1 OS=Homo sapiens OX=9606 GN=DKC1 PE=1 SV=3 4.68 1845.6 - 1.12E+06 - - - -0.6492 - 2.37 0.529 - 205.3 1 2 0 -0.0009 12 0 0 0 2.32E+07 2.22E+07 - - - 6.8294 0.9981 221125_WJC_METTL3_EV_vs_WT_F08.08288.08288.3 0.0577 Dec-44 K.KATVNLLGEEKK.S sp|Q00765|REEP5_HUMAN 1 1328.7664 1.08 113358 8288 3 1328.77075 443.9294 Receptor expression-enhancing protein 5 OS=Homo sapiens OX=9606 GN=REEP5 PE=1 SV=3 8.5 1845.7 - 818826 - - - 3.2993 - 2.285 0.285 - 228.4 1 2 0 0.0044 12 0 0 0 1.94E+07 1.79E+07 - - - 4.0068 0.9997 221125_WJC_METTL3_EV_vs_WT_F08.08290.08290.2 0.175 20-Oct K.NILNKPEVNQK.L "sp|P52732|KIF11_HUMAN,tr|A0A7I2YQY4|A0A7I2YQY4_HUMAN,tr|A0A7I2V3A9|A0A7I2V3A9_HUMAN,tr|A0A7I2V3V3|A0A7I2V3V3_HUMAN" 4 1295.7197 7.7 113360 8290 2 1295.721029 648.8672 Kinesin-like protein KIF11 OS=Homo sapiens OX=9606 GN=KIF11 PE=1 SV=2 8.59 1845.9 - 453407 - - - 0.9871 - 1.921 0.412 - 263.4 1 2 0 0.0013 11 0 0 0 1.86E+07 2.41E+06 - - - 3.8497 0.9995 221125_WJC_METTL3_EV_vs_WT_F08.08298.08298.3 0.189 Dec-40 K.NILNKPEVNQK.L "sp|P52732|KIF11_HUMAN,tr|A0A7I2YQY4|A0A7I2YQY4_HUMAN,tr|A0A7I2V3A9|A0A7I2V3A9_HUMAN,tr|A0A7I2V3V3|A0A7I2V3V3_HUMAN" 4 1295.7197 5.04 113364 8298 3 1295.720342 432.9139 Kinesin-like protein KIF11 OS=Homo sapiens OX=9606 GN=KIF11 PE=1 SV=2 8.59 1846.8 - 8.22E+06 - - - 0.4569 - 2.167 0.272 - 187.7 1 2 0 0.0006 11 0 0 0 1.49E+08 2.97E+07 - - - 3.7693 0.9999 221125_WJC_METTL3_EV_vs_WT_F08.08299.08299.3 7.08E-07 15/40 K.HTVDDGLDIR[166.11]K[136.11].A "sp|Q86VP6|CAND1_HUMAN,tr|A0A0C4DGH5|A0A0C4DGH5_HUMAN" 2 1285.6745 0.3 113365 8299 3 1285.673531 429.5655 Cullin-associated NEDD8-dissociated protein 1 OS=Homo sapiens OX=9606 GN=CAND1 PE=1 SV=2 5.3 1846.9 - 1.02E+06 - - - -0.7801 - 2.152 0.37 - 276.6 1 2 0 -0.001 11 0 0 0 6.78E+06 2.28E+07 - - - 4.8421 0.9967 221125_WJC_METTL3_EV_vs_WT_F08.08302.08302.3 2.86E-06 16/80 V.SAAPGSAAPAAGSAPAAAEEK.K "sp|P05387|RLA2_HUMAN,tr|H0YDD8|H0YDD8_HUMAN" 2 1780.8592 2.05 113368 8302 3 1780.861333 594.627 60S acidic ribosomal protein P2 OS=Homo sapiens OX=9606 GN=RPLP2 PE=1 SV=1 4.53 1847.3 - 289051 - - - 1.2224 - 2.653 0.524 - 244.9 1 1 0 0.0022 21 0 0 0 1.05E+07 5.13E+06 - - - 6.7207 1 221125_WJC_METTL3_EV_vs_WT_F08.08303.08303.2 9.35E-07 15/40 V.SAAPGSAAPAAGSAPAAAEEK[136.11].K "sp|P05387|RLA2_HUMAN,tr|H0YDD8|H0YDD8_HUMAN" 2 1788.8734 1.85 113369 8303 2 1788.870309 895.444 60S acidic ribosomal protein P2 OS=Homo sapiens OX=9606 GN=RPLP2 PE=1 SV=1 4.53 1847.4 - 259111 - - - -1.7033 - 2.738 0.596 - 349.8 1 1 0 -0.003 21 0 0 0 1.27E+07 6.85E+06 - - - 5.9184 0.998 221125_WJC_METTL3_EV_vs_WT_F08.08305.08305.2 0.0721 20-Jun K.NILNK[136.11]PEVNQK[136.11].L "sp|P52732|KIF11_HUMAN,tr|A0A7I2YQY4|A0A7I2YQY4_HUMAN,tr|A0A7I2V3A9|A0A7I2V3A9_HUMAN,tr|A0A7I2V3V3|A0A7I2V3V3_HUMAN" 4 1311.7481 7.7 113371 8305 2 1311.746506 656.8814 Kinesin-like protein KIF11 OS=Homo sapiens OX=9606 GN=KIF11 PE=1 SV=2 8.59 1847.7 - 127048 - - - -1.2533 - 1.53 0.251 - 85.7 1 2 0 -0.0016 11 0 0 0 1.86E+07 2.41E+06 - - - 2.0448 0.9999 221125_WJC_METTL3_EV_vs_WT_F08.08308.08308.3 6.58E-05 Nov-52 R.SAHATAPVNIAGSR.T sp|Q9UQ35|SRRM2_HUMAN 1 1350.7004 0.88 113372 8308 3 1350.700676 451.2407 Serine\arginine repetitive matrix protein 2 OS=Homo sapiens OX=9606 GN=SRRM2 PE=1 SV=2 9.49 1848.1 - 1.28E+06 - - - 0.1962 - 2.137 0.458 - 185.6 1 2 0 0.0003 14 0 0 0 4.55E+07 5.15E+07 - - - 5.6643 0.7986 221125_WJC_METTL3_EV_vs_WT_F08.08312.08312.3 0.494 Jul-44 R.AILQNHTDFKDK.L "sp|Q86X55|CARM1_HUMAN,tr|K7EQA8|K7EQA8_HUMAN" 2 1428.7361 1.69 113376 8312 3 1428.736439 477.2527 Histone-arginine methyltransferase CARM1 OS=Homo sapiens OX=9606 GN=CARM1 PE=1 SV=3 6.79 1848.5 - 706749 - - - 0.2177 - 1.482 0.143 - 34.1 7 2 1 0.0003 12 0 0 0 9.98E+06 5.91E+06 - - - 0.8335 1 221125_WJC_METTL3_EV_vs_WT_F08.08314.08314.2 1.00E-11 19/40 V.SAAPGSAAPAAGSAPAAAEEK.K "sp|P05387|RLA2_HUMAN,tr|H0YDD8|H0YDD8_HUMAN" 2 1780.8592 1.85 113378 8314 2 1780.858218 891.4369 60S acidic ribosomal protein P2 OS=Homo sapiens OX=9606 GN=RPLP2 PE=1 SV=1 4.53 1848.8 - 382606 - - - -0.5267 - 3.671 0.713 - 635.3 1 1 0 -0.0009 21 0 0 0 1.27E+07 6.85E+06 - - - 7.5042 0.957 221125_WJC_METTL3_EV_vs_WT_F08.08318.08318.2 0.0256 16-Aug L.LNKPEVNQK.L "sp|P52732|KIF11_HUMAN,tr|A0A7I2YQY4|A0A7I2YQY4_HUMAN,tr|A0A7I2V3A9|A0A7I2V3A9_HUMAN,tr|A0A7I2V3V3|A0A7I2V3V3_HUMAN" 4 1068.5928 8.01 113380 8318 2 1068.592576 535.3037 Kinesin-like protein KIF11 OS=Homo sapiens OX=9606 GN=KIF11 PE=1 SV=2 8.59 1849.3 - 652393 - - - -0.1703 - 1.41 0.351 - 189.1 1 1 0 -0.0002 9 0 0 0 8.51E+06 1.06E+06 - - - 2.6275 0.9803 221125_WJC_METTL3_EV_vs_WT_F08.08319.08319.3 0.0914 Oct-44 R.SQYEQLAEQNRK.D "sp|P13645|K1C10_HUMAN,tr|A0A1B0GVI3|A0A1B0GVI3_HUMAN" 2 1492.727 138.55 113381 8319 3 1492.723819 498.5829 "Keratin, type I cytoskeletal 10 OS=Homo sapiens OX=9606 GN=KRT10 PE=1 SV=6" 5.86 1849.3 - 2.17E+06 - - - -2.1444 - 1.802 0.147 - 176.1 1 2 0 -0.0032 12 0 0 0 2.35E+08 1.70E+06 - - - 1.8104 0.9999 221125_WJC_METTL3_EV_vs_WT_F08.08325.08325.2 0.000274 28-Nov K.ASTEGVAIQGQQGTR.L sp|Q92621|NU205_HUMAN 1 1501.7485 1.28 113387 8325 2 1501.748428 751.8815 Nuclear pore complex protein Nup205 OS=Homo sapiens OX=9606 GN=NUP205 PE=1 SV=3 6.05 1850 - 149981 - - - -0.0373 - 2.382 0.554 - 371.3 1 2 0 -0.0001 15 0 0 0 1.11E+07 8.68E+06 - - - 5.2667 1 221125_WJC_METTL3_EV_vs_WT_F08.08328.08328.4 2.18E-08 20/78 R.QAGEVTFADAHRPK.L sp|Q13243|SRSF5_HUMAN 1 1525.7637 1.21 113388 8328 4 1525.763629 382.4482 Serine\arginine-rich splicing factor 5 OS=Homo sapiens OX=9606 GN=SRSF5 PE=1 SV=1 6.75 1850.4 - 1.31E+06 - - - -0.0728 - 2.952 0.52 - 386.2 1 2 0 -0.0001 14 0 0 0 3.27E+07 2.71E+07 - - - 4.146 1 221125_WJC_METTL3_EV_vs_WT_F08.08332.08332.2 2.98E-09 19/26 R.NIIHGSDSVESAEK.E sp|P15531|NDKA_HUMAN 1 1484.7107 1.58 113392 8332 2 1484.710341 743.3626 Nucleoside diphosphate kinase A OS=Homo sapiens OX=9606 GN=NME1 PE=1 SV=1 4.65 1850.8 - 583750 - - - -0.2425 - 3.446 0.687 - 1026.9 1 2 0 -0.0004 14 0 0 0 5.13E+07 3.25E+07 - - - 7.2198 0.9972 221125_WJC_METTL3_EV_vs_WT_F08.08333.08333.3 6.01E-07 14/80 V.SAAPGSAAPAAGSAPAAAEEK[136.11].K "sp|P05387|RLA2_HUMAN,tr|H0YDD8|H0YDD8_HUMAN" 2 1788.8734 1.89 113393 8333 3 1788.871901 597.2984 60S acidic ribosomal protein P2 OS=Homo sapiens OX=9606 GN=RPLP2 PE=1 SV=1 4.53 1851 - 398342 - - - -0.8134 - 2.69 0.514 - 159.7 1 1 0 -0.0015 21 0 0 0 9.71E+06 5.13E+06 - - - 6.6426 0.9992 221125_WJC_METTL3_EV_vs_WT_F08.08334.08334.2 0.00264 26-Oct R.NIIHGSDSVESAEK[136.11].E sp|P15531|NDKA_HUMAN 1 1492.7249 1.57 113394 8334 2 1492.720944 747.3697 Nucleoside diphosphate kinase A OS=Homo sapiens OX=9606 GN=NME1 PE=1 SV=1 4.65 1851.1 - 395517 - - - -2.6509 - 1.921 0.435 - 236 1 2 0 -0.004 14 0 0 0 5.11E+07 3.25E+07 - - - 3.891 0.8511 221125_WJC_METTL3_EV_vs_WT_F08.08340.08340.4 0.284 Nov-84 K.LKETGYVVERPSTTK.D "sp|Q9NYF8|BCLF1_HUMAN,tr|E9PKI6|E9PKI6_HUMAN,tr|A0A1W2PQ43|A0A1W2PQ43_HUMAN,tr|E9PK91|E9PK91_HUMAN,tr|E9PK09|E9PK09_HUMAN,tr|E9PQN2|E9PQN2_HUMAN" 6 1706.9203 2.29 113398 8340 4 1706.922933 427.7374 Bcl-2-associated transcription factor 1 OS=Homo sapiens OX=9606 GN=BCLAF1 PE=1 SV=2 8.5 1851.7 - 1.02E+06 - - - 1.5425 - 1.765 0.15 - 73.2 1 2 1 0.0026 15 0 0 0 2.88E+07 1.26E+07 - - - 0.7342 0.9998 221125_WJC_METTL3_EV_vs_WT_F08.08344.08344.2 2.07E-07 13/28 K.ASTEGVAIQGQQGTR[166.11].L sp|Q92621|NU205_HUMAN 1 1511.7568 1.28 113402 8344 2 1511.759039 756.8857 Nuclear pore complex protein Nup205 OS=Homo sapiens OX=9606 GN=NUP205 PE=1 SV=3 6.05 1852.2 - 357767 - - - 1.5115 - 2.63 0.558 - 412.3 1 2 0 0.0023 15 0 0 0 1.11E+07 8.68E+06 - - - 5.539 1 221125_WJC_METTL3_EV_vs_WT_F08.08348.08348.4 2.91E-07 19/78 R.QAGEVTFADAHR[166.11]PK[136.11].L sp|Q13243|SRSF5_HUMAN 1 1543.7862 1.21 113404 8348 4 1543.787921 386.9538 Serine\arginine-rich splicing factor 5 OS=Homo sapiens OX=9606 GN=SRSF5 PE=1 SV=1 6.75 1852.7 - 1.77E+06 - - - 1.1083 - 3.165 0.565 - 322.7 1 2 0 0.0017 14 0 0 0 3.27E+07 2.71E+07 - - - 4.5626 0.7746 221125_WJC_METTL3_EV_vs_WT_F08.08351.08351.3 0.0575 Sep-52 K.IVADKDYSVTANSK.L "sp|P07195|LDHB_HUMAN,tr|A8MW50|A8MW50_HUMAN,tr|A0A3B3IS95|A0A3B3IS95_HUMAN,tr|C9J7H8|C9J7H8_HUMAN,tr|F5H793|F5H793_HUMAN,tr|A0A5F9ZHM4|A0A5F9ZHM4_HUMAN" 6 1509.7675 12.59 113407 8351 3 1509.767553 504.2631 L-lactate dehydrogenase B chain OS=Homo sapiens OX=9606 GN=LDHB PE=1 SV=2 5.96 1852.9 - 493458 - - - 0.0431 - 1.631 0.082 - 75.2 1 2 1 0.0001 14 0 0 0 9.68E+06 7.69E+05 - - - 0.7542 1 221125_WJC_METTL3_EV_vs_WT_F08.08353.08353.3 1.07E-05 14/60 K.ISTETEETEGSLHC[160.03]C[160.03]K[136.11].D sp|Q9Y4E8|UBP15_HUMAN 1 1887.807 0.61 113409 8353 3 1887.807966 630.2763 Ubiquitin carboxyl-terminal hydrolase 15 OS=Homo sapiens OX=9606 GN=USP15 PE=1 SV=3 4.48 1853.2 - 385953 - - - 0.5154 - 2.287 0.537 - 207.1 1 2 0 0.001 16 0 0 0 2.45E+06 3.99E+06 - - - 6.6493 0.9994 221125_WJC_METTL3_EV_vs_WT_F08.08358.08358.3 0.00227 Dec-40 R.TADGIVSHLKK.Q sp|P30101|PDIA3_HUMAN 1 1167.6612 0.62 113412 8358 3 1167.661131 390.2277 Protein disulfide-isomerase A3 OS=Homo sapiens OX=9606 GN=PDIA3 PE=1 SV=4 8.29 1853.8 - 542046 - - - -0.0351 - 1.955 0.288 - 130.8 1 2 0 0 11 0 0 0 3.18E+07 5.16E+07 - - - 3.6554 1 221125_WJC_METTL3_EV_vs_WT_F08.08359.08359.3 1.83E-06 16/44 R.NMSVIAHVDHGK[136.11].S sp|P13639|EF2_HUMAN 1 1314.6594 0.47 113413 8359 3 1314.656294 439.2271 Elongation factor 2 OS=Homo sapiens OX=9606 GN=EEF2 PE=1 SV=4 6.92 1853.9 - 517383 - - - -2.3664 - 2.767 0.551 - 476.5 1 2 0 -0.0031 12 0 0 0 1.21E+08 2.57E+08 - - - 7.5033 0.9998 221125_WJC_METTL3_EV_vs_WT_F08.08360.08360.3 5.82E-07 18/60 R.ASTASASAAVSAARPR.Q "sp|Q7KZI7|MARK2_HUMAN,tr|E7ETY4|E7ETY4_HUMAN,tr|E9PC69|E9PC69_HUMAN,tr|A0A7I2V3R3|A0A7I2V3R3_HUMAN" 4 1472.7696 0.37 113414 8360 3 1472.775728 491.9305 Serine\threonine-protein kinase MARK2 OS=Homo sapiens OX=9606 GN=MARK2 PE=1 SV=2 12 1854.1 - 743229 - - - 4.1928 - 3.078 0.49 - 479.1 1 2 0 0.0062 16 0 0 0 2.85E+07 7.77E+07 - - - 6.8861 1 221125_WJC_METTL3_EV_vs_WT_F08.08364.08364.2 6.94E-06 13/26 R.NNSLQTATENTQAR.V sp|Q5T1M5|FKB15_HUMAN 1 1546.7336 2.86 113418 8364 2 1546.733807 774.3741 FK506-binding protein 15 OS=Homo sapiens OX=9606 GN=FKBP15 PE=1 SV=2 6 1854.5 - 417429 - - - 0.1584 - 2.451 0.641 - 584.4 1 2 0 0.0002 14 0 0 0 1.01E+07 3.53E+06 - - - 6.0251 0.9999 221125_WJC_METTL3_EV_vs_WT_F08.08367.08367.3 0.00186 Oct-32 K.YPHVEDYRR.T "sp|P61289|PSME3_HUMAN,tr|B3KQ25|B3KQ25_HUMAN,tr|K7ESG5|K7ESG5_HUMAN,tr|K9J957|K9J957_HUMAN,tr|A0A087WTV2|A0A087WTV2_HUMAN" 5 1233.5891 1.03 113419 8367 3 1233.589197 412.2036 Proteasome activator complex subunit 3 OS=Homo sapiens OX=9606 GN=PSME3 PE=1 SV=1 6.75 1854.9 - 1.09E+06 - - - 0.103 - 1.662 0.426 - 134.6 1 2 0 0.0001 9 0 0 0 3.95E+07 3.83E+07 - - - 4.8205 0.9999 221125_WJC_METTL3_EV_vs_WT_F08.08368.08368.3 1.57E-05 15/56 K.LKETGYVVERPSTTK.D "sp|Q9NYF8|BCLF1_HUMAN,tr|E9PKI6|E9PKI6_HUMAN,tr|A0A1W2PQ43|A0A1W2PQ43_HUMAN,tr|E9PK91|E9PK91_HUMAN,tr|E9PK09|E9PK09_HUMAN,tr|E9PQN2|E9PQN2_HUMAN" 6 1706.9203 1.94 113420 8368 3 1706.921992 569.9807 Bcl-2-associated transcription factor 1 OS=Homo sapiens OX=9606 GN=BCLAF1 PE=1 SV=2 8.5 1855.1 - 778431 - - - 0.9913 - 2.522 0.55 - 172.4 1 2 1 0.0017 15 0 0 0 1.45E+07 7.51E+06 - - - 7.0853 0.9999 221125_WJC_METTL3_EV_vs_WT_F08.08370.08370.2 2.34E-07 13/26 R.NNSLQTATENTQAR[166.11].V sp|Q5T1M5|FKB15_HUMAN 1 1556.7418 2.86 113422 8370 2 1556.742821 779.3782 FK506-binding protein 15 OS=Homo sapiens OX=9606 GN=FKBP15 PE=1 SV=2 6 1855.3 - 291628 - - - 0.6353 - 2.815 0.55 - 649.1 1 2 0 0.001 14 0 0 0 1.01E+07 3.53E+06 - - - 5.7002 0.9999 221125_WJC_METTL3_EV_vs_WT_F08.08377.08377.3 4.27E-06 13/44 R.NMSVIAHVDHGK.S sp|P13639|EF2_HUMAN 1 1306.6452 0.47 113427 8377 3 1306.647493 436.5557 Elongation factor 2 OS=Homo sapiens OX=9606 GN=EEF2 PE=1 SV=4 6.92 1856.2 - 1.93E+06 - - - 1.751 - 2.282 0.453 - 313 1 2 0 0.0023 12 0 0 0 1.21E+08 2.57E+08 - - - 5.8768 0.998 221125_WJC_METTL3_EV_vs_WT_F08.08378.08378.3 0.00303 Oct-36 K.LLEQYKEESK.K "sp|Q00839|HNRPU_HUMAN,tr|A0A1W2PQL0|A0A1W2PQL0_HUMAN,tr|A0A1W2PPL4|A0A1W2PPL4_HUMAN,tr|Q5RI18|Q5RI18_HUMAN,tr|A0A1W2PP35|A0A1W2PP35_HUMAN,tr|A0A1W2PPS1|A0A1W2PPS1_HUMAN,tr|A0A1W2PPH7|A0A1W2PPH7_HUMAN,tr|A0A1W2PQD4|A0A1W2PQD4_HUMAN,tr|A0A1W2PP34|A0A1W2PP34_HUMAN,tr|A0A1X7SBS1|A0A1X7SBS1_HUMAN" 10 1265.6503 0.79 113428 8378 3 1265.653344 422.8907 Heterogeneous nuclear ribonucleoprotein U OS=Homo sapiens OX=9606 GN=HNRNPU PE=1 SV=6 4.79 1856.3 - 818490 - - - 2.379 - 1.949 0.375 - 184.4 1 2 1 0.003 10 0 0 0 1.56E+07 1.97E+07 - - - 4.6689 0.9984 221125_WJC_METTL3_EV_vs_WT_F08.08383.08383.2 6.06E-06 24-Sep R.ENGQPQNC[160.03]GGQWR.T sp|Q5D862|FILA2_HUMAN 1 1529.643 1047.69 113433 8383 2 1529.635953 765.8288 Filaggrin-2 OS=Homo sapiens OX=9606 GN=FLG2 PE=1 SV=1 6.09 1856.9 - 270098 - - - -4.5893 - 1.658 0.628 - 189.3 1 2 0 -0.007 13 0 0 0 3.54E+07 3.38E+04 - - - 4.9749 1 221125_WJC_METTL3_EV_vs_WT_F08.08389.08389.2 5.75E-08 13/22 R.NMSVIAHVDHGK[136.11].S sp|P13639|EF2_HUMAN 1 1314.6594 0.49 113437 8389 2 1314.659497 658.337 Elongation factor 2 OS=Homo sapiens OX=9606 GN=EEF2 PE=1 SV=4 6.92 1857.7 - 414307 - - - 0.07 - 2.802 0.657 - 799 1 2 0 0.0001 12 0 0 0 6.22E+06 1.27E+07 - - - 6.6046 0.9998 221125_WJC_METTL3_EV_vs_WT_F08.08393.08393.3 0.000122 Nov-44 R.ENPHDAVVFHPK.F "sp|P08397|HEM3_HUMAN,tr|F5GY90|F5GY90_HUMAN,tr|A0A3F2YNY7|A0A3F2YNY7_HUMAN,tr|A0A3B3IRR1|A0A3B3IRR1_HUMAN,tr|A0A3B3IU34|A0A3B3IU34_HUMAN,tr|F5H226|F5H226_HUMAN,tr|F5H345|F5H345_HUMAN,tr|A0A3B3IU56|A0A3B3IU56_HUMAN,tr|F5H0P4|F5H0P4_HUMAN,tr|A0A1W2PNU5|A0A1W2PNU5_HUMAN" 10 1388.6837 2.03 113439 8393 3 1388.686906 463.9018 Porphobilinogen deaminase OS=Homo sapiens OX=9606 GN=HMBS PE=1 SV=2 6 1858.3 - 1.22E+06 - - - 2.3094 - 1.673 0.479 - 133.9 1 2 0 0.0032 12 0 0 0 1.99E+07 9.80E+06 - - - 5.3059 0.9994 221125_WJC_METTL3_EV_vs_WT_F08.08399.08399.2 5.21E-07 22-Nov R.NMSVIAHVDHGK.S sp|P13639|EF2_HUMAN 1 1306.6452 0.49 113445 8399 2 1306.648916 654.3299 Elongation factor 2 OS=Homo sapiens OX=9606 GN=EEF2 PE=1 SV=4 6.92 1858.9 - 272674 - - - 2.8401 - 2.447 0.432 - 503.2 1 2 0 0.0037 12 0 0 0 6.22E+06 1.27E+07 - - - 4.5851 0.9997 221125_WJC_METTL3_EV_vs_WT_F08.08401.08401.3 0.00253 Oct-52 K.HLVQQEGQLEQQER.Q sp|P07476|INVO_HUMAN 1 1720.8493 999 113447 8401 3 1720.851827 574.6237 Involucrin OS=Homo sapiens OX=9606 GN=IVL PE=1 SV=2 4.75 1859.2 - 140809 - - - 1.4917 - 1.99 0.378 - 139.4 1 2 0 0.0026 14 0 0 0 1.66E+06 0.00E+00 - - - 4.5824 0.9947 221125_WJC_METTL3_EV_vs_WT_F08.08406.08406.3 0.39 Jul-44 K.LEDHEYK[136.11]PLDPK[136.11].D "sp|Q8IWX8|CHERP_HUMAN,tr|J3QK89|J3QK89_HUMAN" 2 1498.7639 1.3 113450 8406 3 1498.766699 500.5952 Calcium homeostasis endoplasmic reticulum protein OS=Homo sapiens OX=9606 GN=CHERP PE=1 SV=3 4.75 1859.7 - 1.09E+06 - - - 1.8949 - 1.469 0.267 - 45.9 1 2 0 0.0028 12 0 0 0 4.29E+07 3.31E+07 - - - 2.582 0.9922 221125_WJC_METTL3_EV_vs_WT_F08.08407.08407.3 0.0114 Nov-48 K.IQDK[136.11]EGIPPDQQR[166.11].L "sp|P62979|RS27A_HUMAN,sp|P0CG48|UBC_HUMAN,sp|P0CG48|UBC_HUMAN,sp|P0CG48|UBC_HUMAN,sp|P0CG48|UBC_HUMAN,sp|P0CG48|UBC_HUMAN,sp|P0CG48|UBC_HUMAN,sp|P0CG48|UBC_HUMAN,sp|P0CG48|UBC_HUMAN,sp|P0CG48|UBC_HUMAN,sp|P0CG47|UBB_HUMAN,sp|P0CG47|UBB_HUMAN,sp|P0CG47|UBB_HUMAN,sp|P62987|RL40_HUMAN,tr|F5H388|F5H388_HUMAN,tr|F5H388|F5H388_HUMAN,tr|F5GYU3|F5GYU3_HUMAN,tr|F5GYU3|F5GYU3_HUMAN,tr|B4DV12|B4DV12_HUMAN,tr|B4DV12|B4DV12_HUMAN,tr|J3QSA3|J3QSA3_HUMAN,tr|Q5PY61|Q5PY61_HUMAN,tr|Q5PY61|Q5PY61_HUMAN,tr|Q5PY61|Q5PY61_HUMAN,tr|F5H2Z3|F5H2Z3_HUMAN,tr|F5H2Z3|F5H2Z3_HUMAN,tr|M0R2S1|M0R2S1_HUMAN,tr|J3QS39|J3QS39_HUMAN,tr|J3QTR3|J3QTR3_HUMAN,tr|Q96C32|Q96C32_HUMAN,tr|Q96C32|Q96C32_HUMAN,tr|Q96C32|Q96C32_HUMAN,tr|Q96C32|Q96C32_HUMAN,tr|M0R1V7|M0R1V7_HUMAN,tr|F5H747|F5H747_HUMAN,tr|F5H747|F5H747_HUMAN,tr|F5GXK7|F5GXK7_HUMAN,tr|F5GXK7|F5GXK7_HUMAN,tr|M0R1M6|M0R1M6_HUMAN,tr|F5H6Q2|F5H6Q2_HUMAN,tr|F5H6Q2|F5H6Q2_HUMAN,tr|F5GZ39|F5GZ39_HUMAN,tr|J3QKN0|J3QKN0_HUMAN,tr|J3QKN0|J3QKN0_HUMAN,tr|F5H265|F5H265_HUMAN,tr|F5H265|F5H265_HUMAN,tr|A0A2R8Y422|A0A2R8Y422_HUMAN" 47 1540.7964 0.79 113451 8407 3 1540.799044 514.6061 Ubiquitin-40S ribosomal protein S27a OS=Homo sapiens OX=9606 GN=RPS27A PE=1 SV=2 4.56 1859.7 - 1.32E+06 - - - 1.69 - 1.851 0.274 - 192 1 2 1 0.0026 13 0 0 0 3.00E+07 3.81E+07 - - - 3.2635 1 221125_WJC_METTL3_EV_vs_WT_F08.08408.08408.3 5.04E-06 14/48 R.RAQATAQDPVFQK.L "sp|Q9Y4A5|TRRAP_HUMAN,tr|A0A2R8YFJ4|A0A2R8YFJ4_HUMAN,tr|H0Y4W2|H0Y4W2_HUMAN,tr|F2Z2U4|F2Z2U4_HUMAN" 4 1458.7579 1.06 113452 8408 3 1458.761597 487.2599 Transformation\transcription domain-associated protein OS=Homo sapiens OX=9606 GN=TRRAP PE=1 SV=3 8.75 1859.8 - 899400 - - - 2.5165 - 2.873 0.536 - 359.2 1 2 0 0.0037 13 0 0 0 1.57E+07 1.47E+07 - - - 7.3762 1 221125_WJC_METTL3_EV_vs_WT_F08.08409.08409.2 2.02E-06 14/26 H.LSSSQFSSGSQSSR.D sp|P02533|K1C14_HUMAN 1 1443.659 999 113453 8409 2 1443.662105 722.8368 "Keratin, type I cytoskeletal 14 OS=Homo sapiens OX=9606 GN=KRT14 PE=1 SV=4" 9.75 1860 - 534981 - - - 2.1508 - 2.973 0.558 - 609.3 1 1 0 0.0031 14 0 0 0 3.08E+07 0.00E+00 - - - 5.8956 0.9998 221125_WJC_METTL3_EV_vs_WT_F08.08413.08413.3 6.26E-07 15/48 K.YQELPNSGPPHDR.R "sp|P19525|E2AK2_HUMAN,tr|A0A7P0TAL9|A0A7P0TAL9_HUMAN,tr|A0A7P0Z4M0|A0A7P0Z4M0_HUMAN,tr|A0A7P0TBA9|A0A7P0TBA9_HUMAN" 4 1508.7008 0.82 113456 8413 3 1508.707912 503.9075 "Interferon-induced, double-stranded RNA-activated protein kinase OS=Homo sapiens OX=9606 GN=EIF2AK2 PE=1 SV=2" 5.32 1860.4 - 568650 - - - 4.7107 - 2.951 0.528 - 282 1 2 0 0.0071 13 0 0 0 1.46E+07 1.78E+07 - - - 7.3587 0.984 221125_WJC_METTL3_EV_vs_WT_F08.08415.08415.3 0.000423 Oct-48 D.AHPTLVTYADHSK[136.11].L "sp|Q86U44|MTA70_HUMAN,tr|F5H6D8|F5H6D8_HUMAN,tr|H0YFV6|H0YFV6_HUMAN,tr|B4DTN4|B4DTN4_HUMAN" 4 1446.7347 0.09 113457 8415 3 1446.738939 483.2522 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 6.96 1860.7 - 2.23E+06 - - - 2.9453 - 2.37 0.469 - 132.7 1 1 0 0.0043 13 0 0 0 5.18E+06 5.94E+07 - - - 6.1073 0.9967 221125_WJC_METTL3_EV_vs_WT_F08.08416.08416.3 0.0512 Sep-48 R.K[136.11]VTPNTVLENFFK[136.11].H "sp|Q8IU89|CERS3_HUMAN,tr|H0YN05|H0YN05_HUMAN" 2 1551.8632 0.02 113458 8416 3 1551.862585 518.295 Ceramide synthase 3 OS=Homo sapiens OX=9606 GN=CERS3 PE=1 SV=2 8.59 1860.8 - 429673 - - - -0.3834 - 1.698 0.227 - 111.3 1 2 0 -0.0006 13 0 0 0 1.33E+06 6.36E+07 - - - 2.5062 0.9989 221125_WJC_METTL3_EV_vs_WT_F08.08417.08417.3 0.000782 13/48 K.KQPTPQPPVDC[160.03]VK.T sp|P23490|LORI_HUMAN 1 1492.7708 11.35 113459 8417 3 1492.77874 498.5975 Loricrin OS=Homo sapiens OX=9606 GN=LORICRIN PE=1 SV=2 8.2 1860.8 - 2.15E+06 - - - 5.3196 - 2.761 0.404 - 300.4 1 2 0 0.0079 13 0 0 0 6.55E+07 5.77E+06 - - - 5.7956 0.9937 221125_WJC_METTL3_EV_vs_WT_F08.08420.08420.3 0.019 Oct-32 K.YPHVEDYR[166.11]R[166.11].T "sp|P61289|PSME3_HUMAN,tr|B3KQ25|B3KQ25_HUMAN,tr|K7ESG5|K7ESG5_HUMAN,tr|K9J957|K9J957_HUMAN,tr|A0A087WTV2|A0A087WTV2_HUMAN" 5 1253.6056 1.04 113461 8420 3 1253.609796 418.8758 Proteasome activator complex subunit 3 OS=Homo sapiens OX=9606 GN=PSME3 PE=1 SV=1 6.75 1861.2 - 653592 - - - 3.3392 - 1.747 0.261 - 147.1 1 2 0 0.0042 9 0 0 0 3.83E+07 3.69E+07 - - - 3.1301 0.9717 221125_WJC_METTL3_EV_vs_WT_F08.08423.08423.3 0.00247 Jul-48 K.MMNGGHYTYSENR.V "sp|Q99497|PARK7_HUMAN,tr|K7ELW0|K7ELW0_HUMAN" 2 1558.6293 1.09 113463 8423 3 1558.642147 520.5504 Parkinson disease protein 7 OS=Homo sapiens OX=9606 GN=PARK7 PE=1 SV=2 6.5 1861.6 - 211525 - - - 8.2444 - 1.373 0.432 - 50.2 1 2 0 0.0129 13 0 0 0 3.55E+06 3.24E+06 - - - 4.2123 0.9988 221125_WJC_METTL3_EV_vs_WT_F08.08432.08432.3 0.000676 13/36 K.KRFDTEEEFK.K sp|P54136|SYRC_HUMAN 1 1327.6408 0.83 113469 8432 3 1327.645016 443.5542 "Arginine--tRNA ligase, cytoplasmic OS=Homo sapiens OX=9606 GN=RARS1 PE=1 SV=2" 4.87 1862.7 - 980927 - - - 3.1522 - 2.504 0.398 - 227 1 2 1 0.0042 10 0 0 0 1.79E+07 2.17E+07 - - - 5.6568 0.9985 221125_WJC_METTL3_EV_vs_WT_F08.08437.08437.3 0.000947 Dec-36 K.K[136.11]R[166.11]FDTEEEFK[136.11].K sp|P54136|SYRC_HUMAN 1 1353.6775 0.83 113472 8437 3 1353.682465 452.2331 "Arginine--tRNA ligase, cytoplasmic OS=Homo sapiens OX=9606 GN=RARS1 PE=1 SV=2" 4.87 1863.4 - 1.29E+06 - - - 3.667 - 2.512 0.412 - 202.8 1 2 1 0.005 10 0 0 0 1.78E+07 2.15E+07 - - - 5.822 0.9714 221125_WJC_METTL3_EV_vs_WT_F08.08438.08438.3 0.00477 Jul-40 R.VPLHK[136.11]PTDWQK[136.11].K "sp|Q96A26|F162A_HUMAN,tr|F8W7Q4|F8W7Q4_HUMAN,tr|E9PH05|E9PH05_HUMAN" 3 1363.7583 1.47 113473 8438 3 1363.763278 455.5934 Protein FAM162A OS=Homo sapiens OX=9606 GN=FAM162A PE=1 SV=2 8.57 1863.5 - 458050 - - - 3.6355 - 1.578 0.23 - 47.3 2 2 0 0.005 11 0 0 0 1.69E+07 1.15E+07 - - - 2.2594 0.9531 221125_WJC_METTL3_EV_vs_WT_F08.08444.08444.2 0.00245 20-Jul K.NK[136.11]FDVDAADEK[136.11].F sp|Q9H0D6|XRN2_HUMAN 1 1266.6063 1.07 113477 8444 2 1266.611508 634.3104 5'-3' exoribonuclease 2 OS=Homo sapiens OX=9606 GN=XRN2 PE=1 SV=1 4.23 1864.2 - 55149.4 - - - 4.1149 - 1.47 0.422 - 119.3 1 2 1 0.0052 11 0 0 0 1.17E+06 1.09E+06 - - - 3.1985 0.9997 221125_WJC_METTL3_EV_vs_WT_F08.08445.08445.3 9.01E-07 19/52 K.SINQQSGAHVELQR.N sp|Q96I24|FUBP3_HUMAN 1 1565.791 1.88 113478 8445 3 1565.797383 522.9376 Far upstream element-binding protein 3 OS=Homo sapiens OX=9606 GN=FUBP3 PE=1 SV=2 6.47 1864.3 - 501523 - - - 4.0657 - 3.081 0.433 - 319.4 1 2 0 0.0064 14 0 0 0 7.28E+09 3.87E+09 - - - 6.3562 0.9999 221125_WJC_METTL3_EV_vs_WT_F08.08450.08450.3 6.68E-06 16/52 K.SINQQSGAHVELQR[166.11].N sp|Q96I24|FUBP3_HUMAN 1 1575.7993 1.88 113481 8450 3 1575.805804 526.2737 Far upstream element-binding protein 3 OS=Homo sapiens OX=9606 GN=FUBP3 PE=1 SV=2 6.47 1865 - 1.63E+06 - - - 4.1357 - 3.043 0.541 - 242.5 1 2 0 0.0065 14 0 0 0 7.28E+09 3.87E+09 - - - 7.5272 1 221125_WJC_METTL3_EV_vs_WT_F08.08452.08452.2 1.35E-11 Oct-32 K.GLTTTGNSSLNSTSNTK.V sp|Q96KR1|ZFR_HUMAN 1 1681.8119 1.23 113483 8452 2 1681.817619 841.9132 Zinc finger RNA-binding protein OS=Homo sapiens OX=9606 GN=ZFR PE=1 SV=2 8.75 1865.2 - 251590 - - - 3.4171 - 2.668 0.656 - 292.1 1 2 0 0.0057 17 0 0 0 6.94E+07 5.66E+07 - - - 6.2971 0.9967 221125_WJC_METTL3_EV_vs_WT_F08.08455.08455.3 0.014 Sep-40 K.NKFDVDAADEK.F sp|Q9H0D6|XRN2_HUMAN 1 1250.5779 1.06 113486 8455 3 1250.578432 417.8666 5'-3' exoribonuclease 2 OS=Homo sapiens OX=9606 GN=XRN2 PE=1 SV=1 4.23 1865.6 - 204591 - - - 0.4286 - 1.921 0.283 - 117.5 1 2 1 0.0005 11 0 0 0 4.31E+06 4.06E+06 - - - 3.5496 0.9799 221125_WJC_METTL3_EV_vs_WT_F08.08456.08456.3 0.0977 Aug-40 R.GLDNTEFQGK[136.11]R[166.11].M "sp|Q9BWF3|RBM4_HUMAN,sp|Q9BQ04|RBM4B_HUMAN,tr|E9PB51|E9PB51_HUMAN" 3 1281.6432 0.54 113487 8456 3 1281.64902 428.2217 RNA-binding protein 4 OS=Homo sapiens OX=9606 GN=RBM4 PE=1 SV=1 6.07 1865.7 - 190254 - - - 4.5145 - 1.475 0.294 - 81 1 2 0 0.0058 11 0 0 0 2.83E+06 5.25E+06 - - - 2.9203 0.9108 221125_WJC_METTL3_EV_vs_WT_F08.08457.08457.2 0.0235 24-May K.KQPTPQPPVDC[160.03]VK.T sp|P23490|LORI_HUMAN 1 1492.7708 999 113488 8457 2 1492.77971 747.3927 Loricrin OS=Homo sapiens OX=9606 GN=LORICRIN PE=1 SV=2 8.2 1865.9 - 145216 - - - 5.9694 - 1.26 0.267 - 64.6 1 2 0 0.0089 13 0 0 0 4.49E+06 0.00E+00 - - - 1.6034 1 221125_WJC_METTL3_EV_vs_WT_F08.08459.08459.2 3.47E-07 14/34 R.VGVEASEETPQTSSSSAR.P "sp|Q6Y7W6|GGYF2_HUMAN,tr|A0A7I2V3H7|A0A7I2V3H7_HUMAN,tr|I1E4Y6|I1E4Y6_HUMAN,tr|A0A7I2V516|A0A7I2V516_HUMAN,tr|A0A7I2V3H0|A0A7I2V3H0_HUMAN,tr|C9JHW1|C9JHW1_HUMAN,tr|A0A7I2V361|A0A7I2V361_HUMAN,tr|E7ESB6|E7ESB6_HUMAN" 8 1820.8388 7.22 113490 8459 2 1820.851662 911.4267 GRB10-interacting GYF protein 2 OS=Homo sapiens OX=9606 GN=GIGYF2 PE=1 SV=1 4.25 1866.1 - 110328 - - - 7.0555 - 3.065 0.678 - 381.1 1 1 0 0.0128 18 0 0 0 1.08E+07 1.49E+06 - - - 6.7984 1 221125_WJC_METTL3_EV_vs_WT_F08.08462.08462.2 8.41E-05 18/26 K.K[136.11]GPGEVAGTVTGQK[136.11].R "sp|Q86U44|MTA70_HUMAN,tr|F5H6D8|F5H6D8_HUMAN,tr|H0YFV6|H0YFV6_HUMAN,tr|B4DTN4|B4DTN4_HUMAN" 4 1343.738 -1 113492 8462 2 1343.742524 672.8763 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 8.59 1866.5 - 379930 - - - 3.3824 - 3.329 0.608 - 859.2 1 2 0 0.0045 14 0 0 0 0.00E+00 0.00E+00 - - - 6.5483 0.9999 221125_WJC_METTL3_EV_vs_WT_F08.08465.08465.3 1.04E-05 14/48 K.AFGQSSNLQHHLR[166.11].L sp|Q9NW07|ZN358_HUMAN 1 1503.757 0.46 113494 8465 3 1503.761904 502.2596 Zinc finger protein 358 OS=Homo sapiens OX=9606 GN=ZNF358 PE=1 SV=2 9.81 1866.8 - 816617 - - - 3.2425 - 2.704 0.507 - 221.1 1 2 0 0.0049 13 0 0 0 8.38E+06 1.81E+07 - - - 6.8882 0.9995 221125_WJC_METTL3_EV_vs_WT_F08.08467.08467.3 3.39E-07 14/44 K.AVVGDAQYHHFR.H sp|P47929|LEG7_HUMAN 1 1398.6793 22.01 113496 8467 3 1398.687291 467.2337 Galectin-7 OS=Homo sapiens OX=9606 GN=LGALS7 PE=1 SV=2 6.96 1866.9 - 758016 - - - 5.7261 - 2.743 0.536 - 303.8 1 2 0 0.008 12 0 0 0 7.02E+07 3.19E+06 - - - 7.3106 1 221125_WJC_METTL3_EV_vs_WT_F08.08468.08468.2 1.37E-11 16/32 K.GLTTTGNSSLNSTSNTK[136.11].V sp|Q96KR1|ZFR_HUMAN 1 1689.8261 1.23 113497 8468 2 1689.830701 845.9203 Zinc finger RNA-binding protein OS=Homo sapiens OX=9606 GN=ZFR PE=1 SV=2 8.75 1867.1 - 754096 - - - 2.7393 - 3.499 0.647 - 955.1 1 2 0 0.0046 17 0 0 0 6.94E+07 5.66E+07 - - - 6.8976 0.9659 221125_WJC_METTL3_EV_vs_WT_F08.08469.08469.3 0.0593 Oct-40 K.EKDFSPEALKK.A "sp|O15372|EIF3H_HUMAN,tr|B3KS98|B3KS98_HUMAN,tr|A0A087WZK9|A0A087WZK9_HUMAN,tr|E5RGU4|E5RGU4_HUMAN,tr|E5RJT0|E5RJT0_HUMAN" 5 1290.682 1.65 113498 8469 3 1290.685588 431.2346 Eukaryotic translation initiation factor 3 subunit H OS=Homo sapiens OX=9606 GN=EIF3H PE=1 SV=1 6.28 1867.2 - 474385 - - - 2.8055 - 1.658 0.248 - 121 1 2 1 0.0036 11 0 0 0 1.46E+08 8.87E+07 - - - 2.7403 1 221125_WJC_METTL3_EV_vs_WT_F08.08470.08470.2 4.12E-08 17/26 K.SINQQSGAHVELQR.N sp|Q96I24|FUBP3_HUMAN 1 1565.791 1.87 113499 8470 2 1565.79752 783.9028 Far upstream element-binding protein 3 OS=Homo sapiens OX=9606 GN=FUBP3 PE=1 SV=2 6.47 1867.3 - 391604 - - - 4.1532 - 3.388 0.628 - 1050.8 1 2 0 0.0065 14 0 0 0 3.09E+08 1.66E+08 - - - 6.7395 0.9761 221125_WJC_METTL3_EV_vs_WT_F08.08471.08471.4 0.00845 Oct-78 R.EC[160.03]MHGALSK[136.11]PAVVR[166.11].G "tr|F8W726|F8W726_HUMAN,tr|Q5VU77|Q5VU77_HUMAN" 2 1571.8031 1.84 113500 8471 4 1571.810244 393.9581 Ubiquitin-associated protein 2-like OS=Homo sapiens OX=9606 GN=UBAP2L PE=1 SV=2 8.33 1867.5 - 339922 - - - 4.5305 - 1.755 0.258 - 61.2 1 2 0 0.0071 14 0 0 0 2.25E+07 1.23E+07 - - - 1.6744 1 221125_WJC_METTL3_EV_vs_WT_F08.08473.08473.2 1.05E-09 15/26 K.SINQQSGAHVELQR[166.11].N sp|Q96I24|FUBP3_HUMAN 1 1575.7993 1.87 113502 8473 2 1575.804338 788.9069 Far upstream element-binding protein 3 OS=Homo sapiens OX=9606 GN=FUBP3 PE=1 SV=2 6.47 1867.7 - 232790 - - - 3.2054 - 3.283 0.585 - 852 1 2 0 0.0051 14 0 0 0 3.09E+08 1.66E+08 - - - 6.3434 0.9999 221125_WJC_METTL3_EV_vs_WT_F08.08476.08476.3 2.99E-07 13/52 K.K[136.11]GPGEVAGTVTGQK[136.11].R "sp|Q86U44|MTA70_HUMAN,tr|F5H6D8|F5H6D8_HUMAN,tr|H0YFV6|H0YFV6_HUMAN,tr|B4DTN4|B4DTN4_HUMAN" 4 1343.738 0 113504 8476 3 1343.742125 448.9199 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 8.59 1868.1 - 2.00E+06 - - - 3.0854 - 2.628 0.515 - 269.9 1 2 0 0.0041 14 0 0 0 1.93E+05 6.31E+07 - - - 6.8484 1 221125_WJC_METTL3_EV_vs_WT_F08.08478.08478.2 2.63E-05 16/22 L.NQQSGAHVELQR.N sp|Q96I24|FUBP3_HUMAN 1 1365.6749 1.85 113505 8478 2 1365.675369 683.8447 Far upstream element-binding protein 3 OS=Homo sapiens OX=9606 GN=FUBP3 PE=1 SV=2 6.75 1868.3 - 1.15E+06 - - - 0.3251 - 3.146 0.595 - 1224.4 1 1 0 0.0004 12 0 0 0 1.24E+08 6.68E+07 - - - 6.4512 0.9999 221125_WJC_METTL3_EV_vs_WT_F08.08479.08479.3 6.14E-05 18/48 K.SILEK[136.11]DPSIHQAR[166.11].E "sp|Q99614|TTC1_HUMAN,tr|A0A804HKC5|A0A804HKC5_HUMAN,tr|H0YB37|H0YB37_HUMAN,tr|A0A804HIB8|A0A804HIB8_HUMAN" 4 1510.8223 0.03 113506 8479 3 1510.823047 504.6147 Tetratricopeptide repeat protein 1 OS=Homo sapiens OX=9606 GN=TTC1 PE=1 SV=1 6.47 1868.4 - 832635 - - - 0.5202 - 3.068 0.491 - 404.3 1 2 1 0.0008 13 0 0 0 1.45E+06 5.60E+07 - - - 7.0534 1 221125_WJC_METTL3_EV_vs_WT_F08.08481.08481.3 8.11E-07 17/44 R.ELEAENYHDIKR.L "sp|Q01082|SPTB2_HUMAN,tr|A0A087WUZ3|A0A087WUZ3_HUMAN,tr|F8W6C1|F8W6C1_HUMAN" 3 1515.7318 1.56 113508 8481 3 1515.733318 506.2512 "Spectrin beta chain, non-erythrocytic 1 OS=Homo sapiens OX=9606 GN=SPTBN1 PE=1 SV=2" 4.83 1868.7 - 648833 - - - 1.0206 - 3.053 0.522 - 515.9 1 2 0 0.0015 12 0 0 0 3.31E+07 2.12E+07 - - - 7.4531 1 221125_WJC_METTL3_EV_vs_WT_F08.08482.08482.2 3.00E-07 17/22 L.NQQSGAHVELQR[166.11].N sp|Q96I24|FUBP3_HUMAN 1 1375.6832 1.88 113509 8482 2 1375.683703 688.8489 Far upstream element-binding protein 3 OS=Homo sapiens OX=9606 GN=FUBP3 PE=1 SV=2 6.75 1868.8 - 582392 - - - 0.3693 - 3.175 0.526 - 1433.7 1 1 0 0.0005 12 0 0 0 1.23E+08 6.57E+07 - - - 5.9657 0.9997 221125_WJC_METTL3_EV_vs_WT_F08.08483.08483.3 0.0127 Oct-44 K.TNPPLIQEKPAK.T "sp|P78344|IF4G2_HUMAN,tr|E9PKF8|E9PKF8_HUMAN,tr|H0Y3P2|H0Y3P2_HUMAN,tr|D3DQV9|D3DQV9_HUMAN" 4 1334.7558 3.3 113510 8483 3 1334.757543 445.9259 Eukaryotic translation initiation factor 4 gamma 2 OS=Homo sapiens OX=9606 GN=EIF4G2 PE=1 SV=1 8.26 1868.9 - 529423 - - - 1.3051 - 2.211 0.326 - 110.3 1 2 0 0.0017 12 0 0 0 5.37E+07 1.63E+07 - - - 4.3734 1 221125_WJC_METTL3_EV_vs_WT_F08.08491.08491.4 5.19E-06 15/66 R.ELEAENYHDIK[136.11]R[166.11].L "sp|Q01082|SPTB2_HUMAN,tr|A0A087WUZ3|A0A087WUZ3_HUMAN,tr|F8W6C1|F8W6C1_HUMAN" 3 1533.7542 0.05 113516 8491 4 1533.752629 384.4458 "Spectrin beta chain, non-erythrocytic 1 OS=Homo sapiens OX=9606 GN=SPTBN1 PE=1 SV=2" 4.83 1869.9 - 707689 - - - -1.051 - 2.683 0.519 - 292 1 2 0 -0.0016 12 0 0 0 7.10E+05 1.56E+07 - - - 4.1164 0.9974 221125_WJC_METTL3_EV_vs_WT_F08.08497.08497.3 1.58E-05 14/44 L.NQQSGAHVELQR.N sp|Q96I24|FUBP3_HUMAN 1 1365.6749 1.11 113520 8497 3 1365.672826 456.2323 Far upstream element-binding protein 3 OS=Homo sapiens OX=9606 GN=FUBP3 PE=1 SV=2 6.75 1870.7 - 859793 - - - -1.537 - 2.802 0.516 - 374.5 1 1 0 -0.0021 12 0 0 0 2.02E+07 1.82E+07 - - - 7.1482 1 221125_WJC_METTL3_EV_vs_WT_F08.08498.08498.3 5.91E-08 14/44 R.ELEAENYHDIK[136.11]R[166.11].L "sp|Q01082|SPTB2_HUMAN,tr|A0A087WUZ3|A0A087WUZ3_HUMAN,tr|F8W6C1|F8W6C1_HUMAN" 3 1533.7542 1.56 113521 8498 3 1533.754814 512.2587 "Spectrin beta chain, non-erythrocytic 1 OS=Homo sapiens OX=9606 GN=SPTBN1 PE=1 SV=2" 4.83 1870.7 - 1.21E+06 - - - 0.3736 - 2.96 0.489 - 324.2 1 2 0 0.0006 12 0 0 0 3.31E+07 2.12E+07 - - - 6.9997 0.9794 221125_WJC_METTL3_EV_vs_WT_F08.08501.08501.2 5.58E-07 20-Dec N.QQSGAHVELQR.N sp|Q96I24|FUBP3_HUMAN 1 1251.632 2.07 113524 8501 2 1251.628883 626.8233 Far upstream element-binding protein 3 OS=Homo sapiens OX=9606 GN=FUBP3 PE=1 SV=2 6.75 1871.1 - 538359 - - - -2.488 - 2.411 0.48 - 698.9 1 1 0 -0.0031 11 0 0 0 1.82E+07 8.80E+06 - - - 4.966 0.9425 221125_WJC_METTL3_EV_vs_WT_F08.08502.08502.2 0.0155 20-Oct N.QQSGAHVELQR[166.11].N sp|Q96I24|FUBP3_HUMAN 1 1261.6403 2.05 113525 8502 2 1261.636249 631.8274 Far upstream element-binding protein 3 OS=Homo sapiens OX=9606 GN=FUBP3 PE=1 SV=2 6.75 1871.3 - 382682 - - - -3.1847 - 2.224 0.392 - 443.9 1 1 0 -0.004 11 0 0 0 1.82E+07 8.88E+06 - - - 4.0974 0.9998 221125_WJC_METTL3_EV_vs_WT_F08.08515.08515.3 3.08E-05 Oct-40 R.HLVLAC[160.03]HYDSK[136.11].Y "sp|Q16769|QPCT_HUMAN,tr|B5MCZ9|B5MCZ9_HUMAN,tr|A0A3B3IUD5|A0A3B3IUD5_HUMAN" 3 1349.6642 0.81 113534 8515 3 1349.661427 450.8953 Glutaminyl-peptide cyclotransferase OS=Homo sapiens OX=9606 GN=QPCT PE=1 SV=1 6.91 1872.8 - 1.78E+06 - - - -2.022 - 2.031 0.427 - 103.4 1 2 0 -0.0027 11 0 0 0 4.66E+07 5.79E+07 - - - 5.3127 0.8632 221125_WJC_METTL3_EV_vs_WT_F08.08517.08517.3 0.00992 Oct-48 K.IQDKEGIPPDQQR.L "sp|P62979|RS27A_HUMAN,sp|P0CG48|UBC_HUMAN,sp|P0CG48|UBC_HUMAN,sp|P0CG48|UBC_HUMAN,sp|P0CG48|UBC_HUMAN,sp|P0CG48|UBC_HUMAN,sp|P0CG48|UBC_HUMAN,sp|P0CG48|UBC_HUMAN,sp|P0CG48|UBC_HUMAN,sp|P0CG48|UBC_HUMAN,sp|P0CG47|UBB_HUMAN,sp|P0CG47|UBB_HUMAN,sp|P0CG47|UBB_HUMAN,sp|P62987|RL40_HUMAN,tr|F5H388|F5H388_HUMAN,tr|F5H388|F5H388_HUMAN,tr|F5GYU3|F5GYU3_HUMAN,tr|F5GYU3|F5GYU3_HUMAN,tr|B4DV12|B4DV12_HUMAN,tr|B4DV12|B4DV12_HUMAN,tr|J3QSA3|J3QSA3_HUMAN,tr|Q5PY61|Q5PY61_HUMAN,tr|Q5PY61|Q5PY61_HUMAN,tr|Q5PY61|Q5PY61_HUMAN,tr|F5H2Z3|F5H2Z3_HUMAN,tr|F5H2Z3|F5H2Z3_HUMAN,tr|M0R2S1|M0R2S1_HUMAN,tr|J3QS39|J3QS39_HUMAN,tr|J3QTR3|J3QTR3_HUMAN,tr|Q96C32|Q96C32_HUMAN,tr|Q96C32|Q96C32_HUMAN,tr|Q96C32|Q96C32_HUMAN,tr|Q96C32|Q96C32_HUMAN,tr|M0R1V7|M0R1V7_HUMAN,tr|F5H747|F5H747_HUMAN,tr|F5H747|F5H747_HUMAN,tr|F5GXK7|F5GXK7_HUMAN,tr|F5GXK7|F5GXK7_HUMAN,tr|M0R1M6|M0R1M6_HUMAN,tr|F5H6Q2|F5H6Q2_HUMAN,tr|F5H6Q2|F5H6Q2_HUMAN,tr|F5GZ39|F5GZ39_HUMAN,tr|J3QKN0|J3QKN0_HUMAN,tr|J3QKN0|J3QKN0_HUMAN,tr|F5H265|F5H265_HUMAN,tr|F5H265|F5H265_HUMAN,tr|A0A2R8Y422|A0A2R8Y422_HUMAN" 47 1522.774 0.77 113535 8517 3 1522.779303 508.5986 Ubiquitin-40S ribosomal protein S27a OS=Homo sapiens OX=9606 GN=RPS27A PE=1 SV=2 4.56 1873 - 1.44E+06 - - - 3.5022 - 2.05 0.145 - 166.6 1 2 1 0.0053 13 0 0 0 3.40E+07 4.44E+07 - - - 2.1014 0.9999 221125_WJC_METTL3_EV_vs_WT_F08.08526.08526.3 4.78E-05 Dec-40 K.EFLHAQEEVKR.L sp|P43686|PRS6B_HUMAN 1 1384.7099 0.84 113541 8526 3 1384.707329 462.5772 26S proteasome regulatory subunit 6B OS=Homo sapiens OX=9606 GN=PSMC4 PE=1 SV=2 5.5 1874 - 2.88E+06 - - - -1.8661 - 2.461 0.403 - 239.8 1 2 0 -0.0026 11 0 0 0 8.85E+07 1.05E+08 - - - 5.5907 0.9928 221125_WJC_METTL3_EV_vs_WT_F08.08527.08527.2 6.62E-05 15/24 R.NQELSQSVSSTTR[166.11].P "sp|P82094|TMF1_HUMAN,tr|A0A2R8Y7M0|A0A2R8Y7M0_HUMAN" 2 1445.6986 1.51 113542 8527 2 1445.700198 723.8566 TATA element modulatory factor OS=Homo sapiens OX=9606 GN=TMF1 PE=1 SV=2 6 1874.1 - 656700 - - - 1.1261 - 2.796 0.53 - 1027.7 1 1 0 0.0016 13 0 0 0 1.47E+07 9.70E+06 - - - 5.5939 1 221125_WJC_METTL3_EV_vs_WT_F08.08528.08528.3 3.71E-05 Nov-40 R.HLVLAC[160.03]HYDSK.Y "sp|Q16769|QPCT_HUMAN,tr|B5MCZ9|B5MCZ9_HUMAN,tr|A0A3B3IUD5|A0A3B3IUD5_HUMAN" 3 1341.65 0.79 113543 8528 3 1341.648941 448.2239 Glutaminyl-peptide cyclotransferase OS=Homo sapiens OX=9606 GN=QPCT PE=1 SV=1 6.91 1874.2 - 2.00E+06 - - - -0.7565 - 2.105 0.482 - 121.6 1 2 0 -0.001 11 0 0 0 4.41E+07 5.61E+07 - - - 6.028 0.9995 221125_WJC_METTL3_EV_vs_WT_F08.08530.08530.3 1.43E-07 18/64 K.AVPKEDIYSGGGGGGSR.S sp|Q13151|ROA0_HUMAN 1 1605.7747 1.52 113545 8530 3 1605.768376 536.2655 Heterogeneous nuclear ribonucleoprotein A0 OS=Homo sapiens OX=9606 GN=HNRNPA0 PE=1 SV=1 6.11 1874.3 - 1.17E+06 - - - -3.937 - 2.985 0.562 - 347.3 1 2 1 -0.0063 17 0 0 0 1.09E+08 7.15E+07 - - - 7.5668 1 221125_WJC_METTL3_EV_vs_WT_F08.08531.08531.2 0.00115 15/24 R.NQELSQSVSSTTR.P "sp|P82094|TMF1_HUMAN,tr|A0A2R8Y7M0|A0A2R8Y7M0_HUMAN" 2 1435.6903 1.51 113546 8531 2 1435.684262 718.8524 TATA element modulatory factor OS=Homo sapiens OX=9606 GN=TMF1 PE=1 SV=2 6 1874.4 - 630183 - - - -4.2056 - 2.857 0.553 - 1013 1 1 0 -0.006 13 0 0 0 1.47E+07 9.70E+06 - - - 5.8178 0.991 221125_WJC_METTL3_EV_vs_WT_F08.08533.08533.3 0.0298 Sep-40 K.EK[136.11]DFSPEALK[136.11]K[136.11].A "sp|O15372|EIF3H_HUMAN,tr|B3KS98|B3KS98_HUMAN,tr|A0A087WZK9|A0A087WZK9_HUMAN,tr|E5RGU4|E5RGU4_HUMAN,tr|E5RJT0|E5RJT0_HUMAN" 5 1314.7246 1.66 113547 8533 3 1314.720542 439.2488 Eukaryotic translation initiation factor 3 subunit H OS=Homo sapiens OX=9606 GN=EIF3H PE=1 SV=1 6.28 1874.6 - 2.10E+06 - - - -3.0615 - 1.689 0.34 - 71.4 1 2 1 -0.004 11 0 0 0 1.47E+08 8.87E+07 - - - 3.8185 1 221125_WJC_METTL3_EV_vs_WT_F08.08535.08535.3 1.76E-05 Dec-56 R.ETYVEQEQGENANDR.N "sp|Q9Y2L1|RRP44_HUMAN,tr|F2Z2C0|F2Z2C0_HUMAN" 2 1780.75 5.02 113548 8535 3 1780.751626 594.5906 Exosome complex exonuclease RRP44 OS=Homo sapiens OX=9606 GN=DIS3 PE=1 SV=2 3.91 1874.8 - 298811 - - - 0.9131 - 2.27 0.53 - 203.8 1 2 0 0.0016 15 0 0 0 6.01E+06 1.20E+06 - - - 6.5876 0.9999 221125_WJC_METTL3_EV_vs_WT_F08.08537.08537.3 0.000826 Oct-36 K.KIHLTENGIR.V "sp|Q9P2J5|SYLC_HUMAN,tr|A0A6I8PIV1|A0A6I8PIV1_HUMAN,tr|A0A6I8PRS0|A0A6I8PRS0_HUMAN,tr|A0A6I8PIT3|A0A6I8PIT3_HUMAN,tr|A0A6I8PLB3|A0A6I8PLB3_HUMAN,tr|A0A6I8PS05|A0A6I8PS05_HUMAN,tr|B4DER1|B4DER1_HUMAN,tr|A0A6I8PL42|A0A6I8PL42_HUMAN" 8 1179.6724 0.92 113549 8537 3 1179.671433 394.2314 "Leucine--tRNA ligase, cytoplasmic OS=Homo sapiens OX=9606 GN=LARS1 PE=1 SV=2" 8.75 1875.1 - 1.01E+06 - - - -0.8248 - 2.031 0.389 - 141.9 1 2 0 -0.001 10 0 0 0 2.28E+07 2.46E+07 - - - 4.9459 1 221125_WJC_METTL3_EV_vs_WT_F08.08540.08540.2 4.31E-06 15/28 R.ETYVEQEQGENANDR.N "sp|Q9Y2L1|RRP44_HUMAN,tr|F2Z2C0|F2Z2C0_HUMAN" 2 1780.75 4.79 113551 8540 2 1780.751322 891.3823 Exosome complex exonuclease RRP44 OS=Homo sapiens OX=9606 GN=DIS3 PE=1 SV=2 3.91 1875.4 - 230420 - - - 0.7424 - 2.879 0.7 - 832.9 1 2 0 0.0013 15 0 0 0 6.12E+06 1.28E+06 - - - 6.8106 0.9999 221125_WJC_METTL3_EV_vs_WT_F08.08546.08546.3 6.62E-06 15/60 R.LR[166.11]EDENAEPVGTTYQK[136.11].T "sp|Q16643|DREB_HUMAN,tr|D6R9W4|D6R9W4_HUMAN" 2 1866.9078 0.97 113555 8546 3 1866.906338 623.3099 Drebrin OS=Homo sapiens OX=9606 GN=DBN1 PE=1 SV=4 4.41 1876.2 - 942469 - - - -0.8051 - 2.658 0.487 - 348.5 1 2 1 -0.0015 16 0 0 0 3.16E+07 3.25E+07 - - - 6.4775 0.9944 221125_WJC_METTL3_EV_vs_WT_F08.08548.08548.3 2.43E-05 14/60 R.LREDENAEPVGTTYQK.T "sp|Q16643|DREB_HUMAN,tr|D6R9W4|D6R9W4_HUMAN" 2 1848.8854 0.98 113557 8548 3 1848.881351 617.3024 Drebrin OS=Homo sapiens OX=9606 GN=DBN1 PE=1 SV=4 4.41 1876.4 - 442069 - - - -2.1743 - 2.502 0.25 - 226.5 1 2 1 -0.004 16 0 0 0 3.17E+07 3.25E+07 - - - 3.6793 0.9999 221125_WJC_METTL3_EV_vs_WT_F08.08551.08551.2 1.83E-05 26-Aug K.TEGTQEADQYADEK[136.11].T sp|Q02952|AKA12_HUMAN 1 1591.6729 1.12 113558 8551 2 1591.67232 796.8437 A-kinase anchor protein 12 OS=Homo sapiens OX=9606 GN=AKAP12 PE=1 SV=4 3.83 1876.8 - 135917 - - - -0.3801 - 2.089 0.617 - 206.5 1 2 0 -0.0006 14 0 0 0 1.96E+06 1.76E+06 - - - 5.4466 0.9963 221125_WJC_METTL3_EV_vs_WT_F08.08559.08559.3 0.0177 Aug-48 R.DFGGVTNGKPEDK.L "sp|Q9H845|ACAD9_HUMAN,tr|A0A7P0T871|A0A7P0T871_HUMAN,tr|A0A7P0T7Z1|A0A7P0T7Z1_HUMAN,tr|A0A7P0T9N9|A0A7P0T9N9_HUMAN,tr|A0A7P0T8U3|A0A7P0T8U3_HUMAN,tr|A0A7P0TB58|A0A7P0TB58_HUMAN,tr|Q9H9W4|Q9H9W4_HUMAN,tr|H0Y8Z9|H0Y8Z9_HUMAN" 8 1362.6416 1.38 113563 8559 3 1362.641272 455.2211 "Complex I assembly factor ACAD9, mitochondrial OS=Homo sapiens OX=9606 GN=ACAD9 PE=1 SV=1" 4.56 1877.7 - 1.14E+06 - - - -0.2106 - 1.479 0.253 - 54.3 1 2 0 -0.0003 13 0 0 0 2.23E+07 1.62E+07 - - - 2.4217 0.9816 221125_WJC_METTL3_EV_vs_WT_F08.08561.08561.2 0.00257 22-Oct K.TEADAEK[136.11]TFEEK[136.11].Q "sp|P19338|NUCL_HUMAN,tr|A0A7I2V506|A0A7I2V506_HUMAN,tr|A0A7I2V2U7|A0A7I2V2U7_HUMAN,tr|A0A7I2V3F3|A0A7I2V3F3_HUMAN,tr|A0A7I2V428|A0A7I2V428_HUMAN,tr|A0A7I2V349|A0A7I2V349_HUMAN,tr|H7BY16|H7BY16_HUMAN,tr|A0A7I2V5M5|A0A7I2V5M5_HUMAN,tr|C9JLB1|C9JLB1_HUMAN" 9 1412.6642 1.07 113565 8561 2 1412.658543 707.3394 Nucleolin OS=Homo sapiens OX=9606 GN=NCL PE=1 SV=3 4.25 1878 - 167634 - - - -4.008 - 2.438 0.387 - 290.6 1 2 1 -0.0057 12 0 0 0 5.79E+06 5.41E+06 - - - 4.2424 0.9994 221125_WJC_METTL3_EV_vs_WT_F08.08564.08564.3 0.0272 Oct-48 R.DFGGVTNGK[136.11]PEDK[136.11].L "sp|Q9H845|ACAD9_HUMAN,tr|A0A7P0T871|A0A7P0T871_HUMAN,tr|A0A7P0T7Z1|A0A7P0T7Z1_HUMAN,tr|A0A7P0T9N9|A0A7P0T9N9_HUMAN,tr|A0A7P0T8U3|A0A7P0T8U3_HUMAN,tr|A0A7P0TB58|A0A7P0TB58_HUMAN,tr|Q9H9W4|Q9H9W4_HUMAN,tr|H0Y8Z9|H0Y8Z9_HUMAN" 8 1378.67 1.43 113566 8564 3 1378.669876 460.5639 "Complex I assembly factor ACAD9, mitochondrial OS=Homo sapiens OX=9606 GN=ACAD9 PE=1 SV=1" 4.56 1878.4 - 601684 - - - -0.0602 - 2.017 0.295 - 81.5 1 2 0 -0.0001 13 0 0 0 2.00E+07 1.40E+07 - - - 3.7312 0.999 221125_WJC_METTL3_EV_vs_WT_F08.08565.08565.3 0.0247 Oct-32 K.HWDHLTQVK.K sp|P30084|ECHM_HUMAN 1 1162.5883 1.45 113567 8565 3 1162.589349 388.5367 "Enoyl-CoA hydratase, mitochondrial OS=Homo sapiens OX=9606 GN=ECHS1 PE=1 SV=4" 6.92 1878.5 - 490711 - - - 0.8662 - 1.545 0.315 - 122.2 1 2 0 0.001 9 0 0 0 2.34E+07 1.61E+07 - - - 3.3627 0.9979 221125_WJC_METTL3_EV_vs_WT_F08.08566.08566.3 4.80E-06 Oct-36 L.NTC[160.03]FHMDTC[160.03]K[136.11].Y "sp|Q86U44|MTA70_HUMAN,tr|H0YFV6|H0YFV6_HUMAN" 2 1320.5141 0.02 113568 8566 3 1320.515325 441.1786 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 6.73 1878.6 - 1.11E+06 - - - 0.9557 - 2.021 0.588 - 170.5 1 1 0 0.0013 10 0 0 0 1.46E+06 9.13E+07 - - - 7.1501 0.9989 221125_WJC_METTL3_EV_vs_WT_F08.08567.08567.3 0.00201 Nov-32 K.HWDHLTQVK[136.11].K sp|P30084|ECHM_HUMAN 1 1170.6025 1.56 113569 8567 3 1170.605364 391.2081 "Enoyl-CoA hydratase, mitochondrial OS=Homo sapiens OX=9606 GN=ECHS1 PE=1 SV=4" 6.92 1878.7 - 359333 - - - 2.4107 - 1.511 0.37 - 155 1 2 0 0.0028 9 0 0 0 2.29E+07 1.46E+07 - - - 3.9084 0.9931 221125_WJC_METTL3_EV_vs_WT_F08.08569.08569.2 0.0327 20-Sep K.EKDFSPEALKK.A "sp|O15372|EIF3H_HUMAN,tr|B3KS98|B3KS98_HUMAN,tr|A0A087WZK9|A0A087WZK9_HUMAN,tr|E5RGU4|E5RGU4_HUMAN,tr|E5RJT0|E5RJT0_HUMAN" 5 1290.682 1.52 113571 8569 2 1290.682234 646.3483 Eukaryotic translation initiation factor 3 subunit H OS=Homo sapiens OX=9606 GN=EIF3H PE=1 SV=1 6.28 1879 - 118370 - - - 0.2069 - 1.506 0.363 - 201 1 2 1 0.0003 11 0 0 0 2.99E+06 1.97E+06 - - - 2.8297 1 221125_WJC_METTL3_EV_vs_WT_F08.08570.08570.2 1.31E-06 18-Sep L.NTC[160.03]FHMDTC[160.03]K[136.11].Y "sp|Q86U44|MTA70_HUMAN,tr|H0YFV6|H0YFV6_HUMAN" 2 1320.5141 0.001 113572 8570 2 1320.513901 661.2643 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 6.73 1879.1 - 111810 - - - -0.1227 - 2.006 0.647 - 384.5 1 1 0 -0.0002 10 0 0 0 0.00E+00 9.40E+06 - - - 5.7628 1 221125_WJC_METTL3_EV_vs_WT_F08.08572.08572.3 2.86E-07 17/48 K.HLPSTEPDPHVVR.L "sp|Q9BUJ2|HNRL1_HUMAN,tr|M0QYZ0|M0QYZ0_HUMAN,tr|A0A0A0MRA5|A0A0A0MRA5_HUMAN,tr|M0R3F1|M0R3F1_HUMAN,tr|B7Z4B8|B7Z4B8_HUMAN,tr|M0QYI8|M0QYI8_HUMAN,tr|M0QYM5|M0QYM5_HUMAN" 7 1482.7579 0.94 113573 8572 3 1482.759685 495.2599 Heterogeneous nuclear ribonucleoprotein U-like protein 1 OS=Homo sapiens OX=9606 GN=HNRNPUL1 PE=1 SV=2 5.99 1879.3 - 5.71E+06 - - - 1.1863 - 2.99 0.586 - 467.1 1 2 0 0.0018 13 0 0 0 3.17E+08 3.35E+08 - - - 8.0424 0.9885 221125_WJC_METTL3_EV_vs_WT_F08.08574.08574.3 0.00262 Dec-40 Q.R[166.11]YPDGIISK[136.11]PK[136.11].N sp|Q86U44|MTA70_HUMAN 1 1298.7557 0 113574 8574 3 1298.757707 433.9258 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 9.7 1879.6 - 2.07E+06 - - - 1.5523 - 2.126 0.43 - 255.7 1 1 0 0.002 11 0 0 0 9.12E+04 4.20E+07 - - - 5.4762 0.9996 221125_WJC_METTL3_EV_vs_WT_F08.08575.08575.3 0.00141 Dec-44 K.TEADAEK[136.11]TFEEK[136.11].Q "sp|P19338|NUCL_HUMAN,tr|A0A7I2V506|A0A7I2V506_HUMAN,tr|A0A7I2V2U7|A0A7I2V2U7_HUMAN,tr|A0A7I2V3F3|A0A7I2V3F3_HUMAN,tr|A0A7I2V428|A0A7I2V428_HUMAN,tr|A0A7I2V349|A0A7I2V349_HUMAN,tr|H7BY16|H7BY16_HUMAN,tr|A0A7I2V5M5|A0A7I2V5M5_HUMAN,tr|C9JLB1|C9JLB1_HUMAN" 9 1412.6642 1.18 113575 8575 3 1412.667391 471.8953 Nucleolin OS=Homo sapiens OX=9606 GN=NCL PE=1 SV=3 4.25 1879.6 - 2.07E+06 - - - 2.2553 - 2.482 0.454 - 206.1 1 2 1 0.0032 12 0 0 0 5.77E+07 4.90E+07 - - - 6.1206 0.9997 221125_WJC_METTL3_EV_vs_WT_F08.08584.08584.3 1.39E-06 15/44 K.QR[166.11]YPDGIISK[136.11]PK[136.11].N sp|Q86U44|MTA70_HUMAN 1 1426.8143 0 113582 8584 3 1426.818151 476.612 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 9.7 1880.8 - 2.76E+06 - - - 2.7207 - 2.152 0.581 - 363.2 1 2 1 0.0039 12 0 0 0 1.03E+08 5.44E+10 - - - 7.1408 0.999 221125_WJC_METTL3_EV_vs_WT_F08.08588.08588.2 1.68E-07 15/22 K.TEADAEKTFEEK.Q "sp|P19338|NUCL_HUMAN,tr|A0A7I2V506|A0A7I2V506_HUMAN,tr|A0A7I2V2U7|A0A7I2V2U7_HUMAN,tr|A0A7I2V3F3|A0A7I2V3F3_HUMAN,tr|A0A7I2V428|A0A7I2V428_HUMAN,tr|A0A7I2V349|A0A7I2V349_HUMAN,tr|H7BY16|H7BY16_HUMAN,tr|A0A7I2V5M5|A0A7I2V5M5_HUMAN,tr|C9JLB1|C9JLB1_HUMAN" 9 1396.6358 1.07 113586 8588 2 1396.635884 699.3252 Nucleolin OS=Homo sapiens OX=9606 GN=NCL PE=1 SV=3 4.25 1881.3 - 348733 - - - 0.0566 - 2.867 0.507 - 833.3 1 2 1 0.0001 12 0 0 0 5.79E+06 5.41E+06 - - - 5.557 1 221125_WJC_METTL3_EV_vs_WT_F08.08589.08589.2 3.96E-11 Dec-40 A.AGAAPAGGPAPSTAAAPAEEK.K sp|P05386|RLA1_HUMAN 1 1790.8799 2.77 113587 8589 2 1790.880891 896.4472 60S acidic ribosomal protein P1 OS=Homo sapiens OX=9606 GN=RPLP1 PE=1 SV=1 4.53 1881.4 - 192873 - - - 0.5578 - 2.519 0.676 - 257.6 1 1 0 0.001 21 0 0 0 6.12E+06 2.21E+06 - - - 6.305 0.9931 221125_WJC_METTL3_EV_vs_WT_F08.08590.08590.2 3.56E-05 Oct-40 A.AGAAPAGGPAPSTAAAPAEEK[136.11].K sp|P05386|RLA1_HUMAN 1 1798.8941 2.77 113588 8590 2 1798.894899 900.4543 60S acidic ribosomal protein P1 OS=Homo sapiens OX=9606 GN=RPLP1 PE=1 SV=1 4.53 1881.5 - 143191 - - - 0.4486 - 2.163 0.56 - 162 1 1 0 0.0008 21 0 0 0 6.12E+06 2.21E+06 - - - 5.0737 0.9973 221125_WJC_METTL3_EV_vs_WT_F08.08592.08592.2 0.00467 May-32 K.EAPGPNGATEEDGVPSK.V "sp|P49585|PCY1A_HUMAN,tr|C9J050|C9J050_HUMAN,tr|F8WBU2|F8WBU2_HUMAN,tr|C9JPY0|C9JPY0_HUMAN,tr|F8WAZ5|F8WAZ5_HUMAN,tr|C9JEJ2|C9JEJ2_HUMAN,tr|C9J2E1|C9J2E1_HUMAN,tr|C9JVS0|C9JVS0_HUMAN" 8 1653.7482 3.37 113590 8592 2 1653.744528 827.8814 Choline-phosphate cytidylyltransferase A OS=Homo sapiens OX=9606 GN=PCYT1A PE=1 SV=2 4 1881.8 - 122030 - - - -2.2259 - 1.145 0.399 - 41.5 1 2 0 -0.0037 17 0 0 0 5.36E+06 1.59E+06 - - - 2.3198 0.9643 221125_WJC_METTL3_EV_vs_WT_F08.08594.08594.3 0.000107 Nov-80 A.AGAAPAGGPAPSTAAAPAEEK.K sp|P05386|RLA1_HUMAN 1 1790.8799 5.04 113591 8594 3 1790.884742 597.9672 60S acidic ribosomal protein P1 OS=Homo sapiens OX=9606 GN=RPLP1 PE=1 SV=1 4.53 1882 - 223044 - - - 2.7082 - 2.51 0.389 - 125.4 1 1 0 0.0049 21 0 0 0 3.23E+06 6.40E+05 - - - 5.082 0.999 221125_WJC_METTL3_EV_vs_WT_F08.08596.08596.3 0.0475 Dec-44 K.TEADAEKTFEEK.Q "sp|P19338|NUCL_HUMAN,tr|A0A7I2V506|A0A7I2V506_HUMAN,tr|A0A7I2V2U7|A0A7I2V2U7_HUMAN,tr|A0A7I2V3F3|A0A7I2V3F3_HUMAN,tr|A0A7I2V428|A0A7I2V428_HUMAN,tr|A0A7I2V349|A0A7I2V349_HUMAN,tr|H7BY16|H7BY16_HUMAN,tr|A0A7I2V5M5|A0A7I2V5M5_HUMAN,tr|C9JLB1|C9JLB1_HUMAN" 9 1396.6358 1.16 113592 8596 3 1396.641107 466.5525 Nucleolin OS=Homo sapiens OX=9606 GN=NCL PE=1 SV=3 4.25 1882.2 - 2.63E+06 - - - 3.7963 - 3.036 0.433 - 254.7 1 2 1 0.0053 12 0 0 0 5.69E+07 4.90E+07 - - - 6.4443 0.9999 221125_WJC_METTL3_EV_vs_WT_F08.08598.08598.3 8.88E-09 18/64 R.TPVASTHSISSAATPDR.L "sp|P27448|MARK3_HUMAN,tr|A0A7I2V3I9|A0A7I2V3I9_HUMAN,tr|H0YIY6|H0YIY6_HUMAN,tr|A0A7I2V5G3|A0A7I2V5G3_HUMAN,tr|A0A7I2YQF4|A0A7I2YQF4_HUMAN,tr|A0A7I2YQF7|A0A7I2YQF7_HUMAN,tr|A0A7I2V4K8|A0A7I2V4K8_HUMAN,tr|A0A7I2V2U9|A0A7I2V2U9_HUMAN,tr|A0A7I2V4G7|A0A7I2V4G7_HUMAN,tr|A0A7I2V2N8|A0A7I2V2N8_HUMAN,tr|H0YJI9|H0YJI9_HUMAN,tr|A0A7I2V409|A0A7I2V409_HUMAN,tr|A0A7I2V4T2|A0A7I2V4T2_HUMAN,tr|A0A7I2V549|A0A7I2V549_HUMAN,tr|A0A7I2V3B9|A0A7I2V3B9_HUMAN,tr|A0A7I2V602|A0A7I2V602_HUMAN,tr|A0A7I2V639|A0A7I2V639_HUMAN,tr|A0A7I2V2E3|A0A7I2V2E3_HUMAN,tr|J3KNR0|J3KNR0_HUMAN,tr|H0YKP9|H0YKP9_HUMAN" 20 1696.838 1.07 113594 8598 3 1696.841838 566.62 MAP\microtubule affinity-regulating kinase 3 OS=Homo sapiens OX=9606 GN=MARK3 PE=1 SV=5 6.41 1882.5 - 542615 - - - 2.2459 - 3.498 0.459 - 372.7 1 2 0 0.0038 17 0 0 0 6.43E+07 5.99E+07 - - - 6.8198 0.9999 221125_WJC_METTL3_EV_vs_WT_F08.08599.08599.3 2.50E-07 19/64 R.TPVASTHSISSAATPDR[166.11].L "sp|P27448|MARK3_HUMAN,tr|A0A7I2V3I9|A0A7I2V3I9_HUMAN,tr|H0YIY6|H0YIY6_HUMAN,tr|A0A7I2V5G3|A0A7I2V5G3_HUMAN,tr|A0A7I2YQF4|A0A7I2YQF4_HUMAN,tr|A0A7I2YQF7|A0A7I2YQF7_HUMAN,tr|A0A7I2V4K8|A0A7I2V4K8_HUMAN,tr|A0A7I2V2U9|A0A7I2V2U9_HUMAN,tr|A0A7I2V4G7|A0A7I2V4G7_HUMAN,tr|A0A7I2V2N8|A0A7I2V2N8_HUMAN,tr|H0YJI9|H0YJI9_HUMAN,tr|A0A7I2V409|A0A7I2V409_HUMAN,tr|A0A7I2V4T2|A0A7I2V4T2_HUMAN,tr|A0A7I2V549|A0A7I2V549_HUMAN,tr|A0A7I2V3B9|A0A7I2V3B9_HUMAN,tr|A0A7I2V602|A0A7I2V602_HUMAN,tr|A0A7I2V639|A0A7I2V639_HUMAN,tr|A0A7I2V2E3|A0A7I2V2E3_HUMAN,tr|J3KNR0|J3KNR0_HUMAN,tr|H0YKP9|H0YKP9_HUMAN" 20 1706.8463 1.14 113595 8599 3 1706.852475 569.956 MAP\microtubule affinity-regulating kinase 3 OS=Homo sapiens OX=9606 GN=MARK3 PE=1 SV=5 6.41 1882.6 - 519622 - - - 3.6195 - 3.281 0.469 - 568.2 1 2 0 0.0062 17 0 0 0 6.80E+07 5.99E+07 - - - 6.7688 1 221125_WJC_METTL3_EV_vs_WT_F08.08603.08603.2 1.83E-11 20/24 R.KGDEVDGVDEVAK.K "sp|P09874|PARP1_HUMAN,tr|A0A7I2V5E9|A0A7I2V5E9_HUMAN,tr|A0A7I2V625|A0A7I2V625_HUMAN,tr|A0A7I2V3E1|A0A7I2V3E1_HUMAN" 4 1359.6518 1.23 113599 8603 2 1359.656456 680.8332 Poly [ADP-ribose] polymerase 1 OS=Homo sapiens OX=9606 GN=PARP1 PE=1 SV=4 4.11 1883.2 - 250467 - - - 3.4325 - 3.925 0.674 - 1606.4 1 2 0 0.0047 13 0 0 0 5.57E+07 4.53E+07 - - - 7.5271 0.8831 221125_WJC_METTL3_EV_vs_WT_F08.08604.08604.2 0.0774 24-Jun K.HLPSTEPDPHVVR.L "sp|Q9BUJ2|HNRL1_HUMAN,tr|M0QYZ0|M0QYZ0_HUMAN,tr|A0A0A0MRA5|A0A0A0MRA5_HUMAN,tr|M0R3F1|M0R3F1_HUMAN,tr|B7Z4B8|B7Z4B8_HUMAN,tr|M0QYI8|M0QYI8_HUMAN,tr|M0QYM5|M0QYM5_HUMAN" 7 1482.7579 2.31 113600 8604 2 1482.765419 742.3862 Heterogeneous nuclear ribonucleoprotein U-like protein 1 OS=Homo sapiens OX=9606 GN=HNRNPUL1 PE=1 SV=2 5.99 1883.3 - 100865 - - - 5.0534 - 1.071 0.232 - 91.3 1 2 0 0.0075 13 0 0 0 3.31E+06 1.43E+06 - - - 0.9282 1 221125_WJC_METTL3_EV_vs_WT_F08.08607.08607.3 5.69E-07 13/48 R.KGDEVDGVDEVAK.K "sp|P09874|PARP1_HUMAN,tr|A0A7I2V5E9|A0A7I2V5E9_HUMAN,tr|A0A7I2V625|A0A7I2V625_HUMAN,tr|A0A7I2V3E1|A0A7I2V3E1_HUMAN" 4 1359.6518 1.21 113601 8607 3 1359.651847 454.2245 Poly [ADP-ribose] polymerase 1 OS=Homo sapiens OX=9606 GN=PARP1 PE=1 SV=4 4.11 1883.7 - 1.93E+06 - - - 0.0427 - 2.417 0.532 - 252.2 1 2 0 0.0001 13 0 0 0 1.02E+08 8.41E+07 - - - 6.864 0.9963 221125_WJC_METTL3_EV_vs_WT_F08.08611.08611.2 0.0361 22-Dec K.QR[166.11]YPDGIISK[136.11]PK[136.11].N sp|Q86U44|MTA70_HUMAN 1 1426.8143 -1 113605 8611 2 1426.816224 714.4144 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 9.7 1884.2 - 507621 - - - 1.3702 - 2.304 0.377 - 339.6 1 2 1 0.002 12 0 0 0 0.00E+00 0.00E+00 - - - 4.021 0.9999 221125_WJC_METTL3_EV_vs_WT_F08.08615.08615.2 3.46E-05 13/30 R.GQSPAGDGSPEPPTPR.Y "sp|Q9H6R4|NOL6_HUMAN,tr|A0A0A0MRW6|A0A0A0MRW6_HUMAN" 2 1548.7168 1.12 113606 8615 2 1548.718167 775.3657 Nucleolar protein 6 OS=Homo sapiens OX=9606 GN=NOL6 PE=1 SV=2 4.37 1884.7 - 827223 - - - 0.851 - 2.622 0.519 - 452.3 1 2 0 0.0013 16 0 0 0 7.65E+07 6.82E+07 - - - 5.2438 0.9997 221125_WJC_METTL3_EV_vs_WT_F08.08620.08620.3 1.80E-05 13/44 K.QR[166.11]YPDGIISKPK[136.11].N sp|Q86U44|MTA70_HUMAN 1 1418.8001 - 113609 8620 3 1418.803804 473.9406 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 9.7 1885.4 - 2.00E+06 - - - 2.6325 - 2.664 0.495 - 246.8 1 2 1 0.0037 12 0 0 0 - - - - - 6.7737 0.9999 221125_WJC_METTL3_EV_vs_WT_F08.08625.08625.2 1.88E-06 30-Nov R.GQSPAGDGSPEPPTPR[166.11].Y "sp|Q9H6R4|NOL6_HUMAN,tr|A0A0A0MRW6|A0A0A0MRW6_HUMAN" 2 1558.7251 1.13 113613 8625 2 1558.725921 780.3698 Nucleolar protein 6 OS=Homo sapiens OX=9606 GN=NOL6 PE=1 SV=2 4.37 1886 - 445363 - - - 0.5145 - 2.448 0.545 - 271.2 1 2 0 0.0008 16 0 0 0 7.65E+07 6.80E+07 - - - 5.2672 0.9989 221125_WJC_METTL3_EV_vs_WT_F08.08631.08631.3 4.52E-05 13/56 R.ALDHAMSVASDHNVK.E sp|Q9Y5B6|PAXB1_HUMAN 1 1593.7569 0.99 113618 8631 3 1593.763449 532.2596 PAX3- and PAX7-binding protein 1 OS=Homo sapiens OX=9606 GN=PAXBP1 PE=1 SV=2 5.98 1886.6 - 330531 - - - 4.0841 - 2.189 0.39 - 189.9 1 2 0 0.0065 15 0 0 0 5.76E+06 5.80E+06 - - - 4.9306 0.9848 221125_WJC_METTL3_EV_vs_WT_F08.08635.08635.2 10.8 14-Aug P.DGIISK[136.11]PK[136.11].N sp|Q86U44|MTA70_HUMAN 1 872.5302 0 113620 8635 2 872.530013 437.2724 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 8.59 1887.1 - 1.82E+06 - - - -0.2349 - 1.884 0.38 - 187.2 1 1 0 -0.0002 8 0 0 0 5.73E+05 8.01E+08 - - - 3.7579 0.991 221125_WJC_METTL3_EV_vs_WT_F08.08636.08636.2 0.000852 16-Dec Y.PDGIISK[136.11]PK[136.11].N sp|Q86U44|MTA70_HUMAN 1 969.583 0 113621 8636 2 969.582072 485.7988 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 9.01 1887.2 - 1.75E+06 - - - -0.9385 - 2.307 0.443 - 482.9 1 1 0 -0.0009 9 0 0 0 1.51E+06 7.44E+08 - - - 4.7312 0.9999 221125_WJC_METTL3_EV_vs_WT_F08.08650.08650.3 0.000794 14/48 K.KGTVEGFEPADNK.C "sp|P37108|SRP14_HUMAN,tr|H0YLA2|H0YLA2_HUMAN" 2 1390.6729 1.28 113632 8650 3 1390.674427 464.5649 Signal recognition particle 14 kDa protein OS=Homo sapiens OX=9606 GN=SRP14 PE=1 SV=2 4.68 1888.8 - 2.76E+06 - - - 1.1275 - 2.384 0.461 - 236.4 1 2 0 0.0016 13 0 0 0 9.49E+08 7.40E+08 - - - 6.0348 1 221125_WJC_METTL3_EV_vs_WT_F08.08654.08654.2 4.51E-10 16/24 K.KGTVEGFEPADNK.C "sp|P37108|SRP14_HUMAN,tr|H0YLA2|H0YLA2_HUMAN" 2 1390.6729 1.31 113635 8654 2 1390.672367 696.3437 Signal recognition particle 14 kDa protein OS=Homo sapiens OX=9606 GN=SRP14 PE=1 SV=2 4.68 1889.3 - 446763 - - - -0.3538 - 2.952 0.533 - 874.2 1 2 0 -0.0005 13 0 0 0 2.08E+08 1.58E+08 - - - 5.7558 0.9999 221125_WJC_METTL3_EV_vs_WT_F08.08655.08655.2 2.18E-06 15/24 K.K[136.11]GTVEGFEPADNK[136.11].C "sp|P37108|SRP14_HUMAN,tr|H0YLA2|H0YLA2_HUMAN" 2 1406.7013 1.31 113636 8655 2 1406.70041 704.3579 Signal recognition particle 14 kDa protein OS=Homo sapiens OX=9606 GN=SRP14 PE=1 SV=2 4.68 1889.4 - 377919 - - - -0.6035 - 2.778 0.454 - 666.7 1 2 0 -0.0008 13 0 0 0 2.08E+08 1.58E+08 - - - 5.0163 0.9989 221125_WJC_METTL3_EV_vs_WT_F08.08662.08662.3 0.0819 Nov-48 K.IQDK[136.11]EGIPPDQQR[166.11].L "sp|P62979|RS27A_HUMAN,sp|P0CG48|UBC_HUMAN,sp|P0CG48|UBC_HUMAN,sp|P0CG48|UBC_HUMAN,sp|P0CG48|UBC_HUMAN,sp|P0CG48|UBC_HUMAN,sp|P0CG48|UBC_HUMAN,sp|P0CG48|UBC_HUMAN,sp|P0CG48|UBC_HUMAN,sp|P0CG48|UBC_HUMAN,sp|P0CG47|UBB_HUMAN,sp|P0CG47|UBB_HUMAN,sp|P0CG47|UBB_HUMAN,sp|P62987|RL40_HUMAN,tr|F5H388|F5H388_HUMAN,tr|F5H388|F5H388_HUMAN,tr|F5GYU3|F5GYU3_HUMAN,tr|F5GYU3|F5GYU3_HUMAN,tr|B4DV12|B4DV12_HUMAN,tr|B4DV12|B4DV12_HUMAN,tr|J3QSA3|J3QSA3_HUMAN,tr|Q5PY61|Q5PY61_HUMAN,tr|Q5PY61|Q5PY61_HUMAN,tr|Q5PY61|Q5PY61_HUMAN,tr|F5H2Z3|F5H2Z3_HUMAN,tr|F5H2Z3|F5H2Z3_HUMAN,tr|M0R2S1|M0R2S1_HUMAN,tr|J3QS39|J3QS39_HUMAN,tr|J3QTR3|J3QTR3_HUMAN,tr|Q96C32|Q96C32_HUMAN,tr|Q96C32|Q96C32_HUMAN,tr|Q96C32|Q96C32_HUMAN,tr|Q96C32|Q96C32_HUMAN,tr|M0R1V7|M0R1V7_HUMAN,tr|F5H747|F5H747_HUMAN,tr|F5H747|F5H747_HUMAN,tr|F5GXK7|F5GXK7_HUMAN,tr|F5GXK7|F5GXK7_HUMAN,tr|M0R1M6|M0R1M6_HUMAN,tr|F5H6Q2|F5H6Q2_HUMAN,tr|F5H6Q2|F5H6Q2_HUMAN,tr|F5GZ39|F5GZ39_HUMAN,tr|J3QKN0|J3QKN0_HUMAN,tr|J3QKN0|J3QKN0_HUMAN,tr|F5H265|F5H265_HUMAN,tr|F5H265|F5H265_HUMAN,tr|A0A2R8Y422|A0A2R8Y422_HUMAN" 47 1540.7964 0.15 113641 8662 3 1540.795496 514.6061 Ubiquitin-40S ribosomal protein S27a OS=Homo sapiens OX=9606 GN=RPS27A PE=1 SV=2 4.56 1890.1 - 1.45E+06 - - - -0.6127 - 2.068 0.35 - 166.7 1 2 1 -0.0009 13 0 0 0 3.65E+07 2.45E+08 - - - 4.4119 0.9999 221125_WJC_METTL3_EV_vs_WT_F08.08673.08673.3 1.12E-05 14/36 R.HLEFSHDQYR.E sp|Q9NR45|SIAS_HUMAN 1 1330.6054 0.33 113647 8673 3 1330.601599 444.5424 Sialic acid synthase OS=Homo sapiens OX=9606 GN=NANS PE=1 SV=2 5.99 1891.5 - 531006 - - - -2.8927 - 2.18 0.53 - 234.5 1 2 0 -0.0039 10 0 0 0 1.50E+07 4.54E+07 - - - 6.7239 0.9999 221125_WJC_METTL3_EV_vs_WT_F08.08682.08682.3 0.00204 13/52 K.TLTDEVNSPDSDRR.D "sp|Q8TAQ2|SMRC2_HUMAN,tr|F8VXC8|F8VXC8_HUMAN" 2 1603.7438 1.4 113652 8682 3 1603.744371 535.5885 SWI\SNF complex subunit SMARCC2 OS=Homo sapiens OX=9606 GN=SMARCC2 PE=1 SV=1 4.23 1892.7 - 1.47E+06 - - - 0.361 - 1.909 0.454 - 142.3 1 2 0 0.0006 14 0 0 0 8.49E+07 6.08E+07 - - - 5.3198 0.9999 221125_WJC_METTL3_EV_vs_WT_F08.08693.08693.2 0.0392 13/18 R.YPDGIISK[136.11]PK[136.11].N sp|Q86U44|MTA70_HUMAN 1 1132.6463 0.001 113657 8693 2 1132.644763 567.3304 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 8.5 1894.1 - 1.21E+06 - - - -1.3658 - 2.149 0.539 - 604 1 2 0 -0.0015 10 0 0 0 0.00E+00 5.05E+07 - - - 5.1569 0.9998 221125_WJC_METTL3_EV_vs_WT_F08.08699.08699.3 0.000159 17/56 K.IK[136.11]SEHPGLSIGDTAK[136.11].K "sp|P26583|HMGB2_HUMAN,tr|D6R9A6|D6R9A6_HUMAN" 2 1567.8541 0.14 113660 8699 3 1567.851337 523.6253 High mobility group protein B2 OS=Homo sapiens OX=9606 GN=HMGB2 PE=1 SV=2 6.75 1894.8 - 2.06E+06 - - - -1.7438 - 3.021 0.443 - 216.4 1 2 1 -0.0027 15 0 0 0 1.57E+07 1.11E+08 - - - 6.3631 0.9551 221125_WJC_METTL3_EV_vs_WT_F08.08701.08701.4 0.019 14/84 K.IK[136.11]SEHPGLSIGDTAK[136.11].K "sp|P26583|HMGB2_HUMAN,tr|D6R9A6|D6R9A6_HUMAN" 2 1567.8541 0.17 113662 8701 4 1567.851317 392.9708 High mobility group protein B2 OS=Homo sapiens OX=9606 GN=HMGB2 PE=1 SV=2 6.75 1895.1 - 1.59E+06 - - - -1.7565 - 1.864 0.2 - 69.5 1 2 1 -0.0028 15 0 0 0 6.54E+06 3.85E+07 - - - 1.1889 0.9964 221125_WJC_METTL3_EV_vs_WT_F08.08706.08706.3 0.0233 Nov-36 R.DREEALHQFR.S "sp|O00571|DDX3X_HUMAN,sp|O15523|DDX3Y_HUMAN,tr|A0A2R8YFR4|A0A2R8YFR4_HUMAN,tr|A0A2R8YCW1|A0A2R8YCW1_HUMAN,tr|A0A2R8YDH3|A0A2R8YDH3_HUMAN,tr|A0A2R8YDT5|A0A2R8YDT5_HUMAN,tr|A0A2R8Y645|A0A2R8Y645_HUMAN,tr|A0A2R8YF78|A0A2R8YF78_HUMAN,tr|A0A0D9SFB3|A0A0D9SFB3_HUMAN,tr|A0A2R8YFS5|A0A2R8YFS5_HUMAN,tr|A0A0D9SF53|A0A0D9SF53_HUMAN,tr|A0A087WVZ1|A0A087WVZ1_HUMAN,tr|A0A0J9YVQ7|A0A0J9YVQ7_HUMAN,tr|A0A2R8Y5G6|A0A2R8Y5G6_HUMAN,tr|A0A2R8Y7T2|A0A2R8Y7T2_HUMAN,tr|A0A0D9SG12|A0A0D9SG12_HUMAN,tr|F6S8Q4|F6S8Q4_HUMAN,tr|A0A2U3TZJ9|A0A2U3TZJ9_HUMAN,tr|A0A2R8Y4A4|A0A2R8Y4A4_HUMAN" 19 1299.632 1.19 113663 8706 3 1299.630131 434.2179 ATP-dependent RNA helicase DDX3X OS=Homo sapiens OX=9606 GN=DDX3X PE=1 SV=3 5.45 1895.8 - 5.59E+06 - - - -1.4358 - 1.738 0.314 - 216.6 1 2 1 -0.0019 10 0 0 0 9.57E+08 8.03E+08 - - - 3.6545 0.9998 221125_WJC_METTL3_EV_vs_WT_F08.08713.08713.2 0.265 28-Dec K.SVSIQEEQSAPSSEK.G "sp|Q86XZ4|SPAS2_HUMAN,tr|F8VS10|F8VS10_HUMAN" 2 1604.753 2.85 113667 8713 2 1604.751454 803.3838 Spermatogenesis-associated serine-rich protein 2 OS=Homo sapiens OX=9606 GN=SPATS2 PE=1 SV=1 4.25 1896.7 - 1.11E+06 - - - -0.9385 - 2.609 0.452 - 365.7 1 2 0 -0.0015 15 0 0 0 3.11E+07 1.09E+07 - - - 4.7367 0.9994 221125_WJC_METTL3_EV_vs_WT_F08.08718.08718.3 0.00541 14/52 K.TLTDEVNSPDSDR[166.11]R[166.11].D "sp|Q8TAQ2|SMRC2_HUMAN,tr|F8VXC8|F8VXC8_HUMAN" 2 1623.7603 1.37 113670 8718 3 1623.758545 542.2607 SWI\SNF complex subunit SMARCC2 OS=Homo sapiens OX=9606 GN=SMARCC2 PE=1 SV=1 4.23 1897.3 - 2.15E+06 - - - -1.1005 - 1.638 0.347 - 95.6 1 2 0 -0.0018 14 0 0 0 8.55E+07 6.23E+07 - - - 3.7196 0.994 221125_WJC_METTL3_EV_vs_WT_F08.08719.08719.3 0.0362 Dec-48 K.LSSAENDR[166.11]DILR[166.11]R[166.11].E "sp|Q15643|TRIPB_HUMAN,tr|H0YJ97|H0YJ97_HUMAN" 2 1573.8315 1.36 113671 8719 3 1573.828054 525.6178 Thyroid receptor-interacting protein 11 OS=Homo sapiens OX=9606 GN=TRIP11 PE=1 SV=3 6.12 1897.4 - 2.69E+06 - - - -2.1749 - 2.153 0.271 - 168.9 1 2 1 -0.0034 13 0 0 0 1.70E+08 1.25E+08 - - - 3.6396 0.9984 221125_WJC_METTL3_EV_vs_WT_F08.08721.08721.2 8.24E-06 18-Dec R.DREEALHQFR.S "sp|O00571|DDX3X_HUMAN,sp|O15523|DDX3Y_HUMAN,tr|A0A2R8YFR4|A0A2R8YFR4_HUMAN,tr|A0A2R8YCW1|A0A2R8YCW1_HUMAN,tr|A0A2R8YDH3|A0A2R8YDH3_HUMAN,tr|A0A2R8YDT5|A0A2R8YDT5_HUMAN,tr|A0A2R8Y645|A0A2R8Y645_HUMAN,tr|A0A2R8YF78|A0A2R8YF78_HUMAN,tr|A0A0D9SFB3|A0A0D9SFB3_HUMAN,tr|A0A2R8YFS5|A0A2R8YFS5_HUMAN,tr|A0A0D9SF53|A0A0D9SF53_HUMAN,tr|A0A087WVZ1|A0A087WVZ1_HUMAN,tr|A0A0J9YVQ7|A0A0J9YVQ7_HUMAN,tr|A0A2R8Y5G6|A0A2R8Y5G6_HUMAN,tr|A0A2R8Y7T2|A0A2R8Y7T2_HUMAN,tr|A0A0D9SG12|A0A0D9SG12_HUMAN,tr|F6S8Q4|F6S8Q4_HUMAN,tr|A0A2U3TZJ9|A0A2U3TZJ9_HUMAN,tr|A0A2R8Y4A4|A0A2R8Y4A4_HUMAN" 19 1299.632 1.13 113673 8721 2 1299.630746 650.8233 ATP-dependent RNA helicase DDX3X OS=Homo sapiens OX=9606 GN=DDX3X PE=1 SV=3 5.45 1897.6 - 1.11E+06 - - - -0.9626 - 1.878 0.542 - 223.2 1 2 1 -0.0013 10 0 0 0 5.89E+07 5.22E+07 - - - 4.8029 1 221125_WJC_METTL3_EV_vs_WT_F08.08722.08722.2 1.53E-07 15/18 R.DR[166.11]EEALHQFR[166.11].S "sp|O00571|DDX3X_HUMAN,sp|O15523|DDX3Y_HUMAN,tr|A0A2R8YFR4|A0A2R8YFR4_HUMAN,tr|A0A2R8YCW1|A0A2R8YCW1_HUMAN,tr|A0A2R8YDH3|A0A2R8YDH3_HUMAN,tr|A0A2R8YDT5|A0A2R8YDT5_HUMAN,tr|A0A2R8Y645|A0A2R8Y645_HUMAN,tr|A0A2R8YF78|A0A2R8YF78_HUMAN,tr|A0A0D9SFB3|A0A0D9SFB3_HUMAN,tr|A0A2R8YFS5|A0A2R8YFS5_HUMAN,tr|A0A0D9SF53|A0A0D9SF53_HUMAN,tr|A0A087WVZ1|A0A087WVZ1_HUMAN,tr|A0A0J9YVQ7|A0A0J9YVQ7_HUMAN,tr|A0A2R8Y5G6|A0A2R8Y5G6_HUMAN,tr|A0A2R8Y7T2|A0A2R8Y7T2_HUMAN,tr|A0A0D9SG12|A0A0D9SG12_HUMAN,tr|F6S8Q4|F6S8Q4_HUMAN,tr|A0A2U3TZJ9|A0A2U3TZJ9_HUMAN,tr|A0A2R8Y4A4|A0A2R8Y4A4_HUMAN" 19 1319.6485 1.13 113674 8722 2 1319.64783 660.8315 ATP-dependent RNA helicase DDX3X OS=Homo sapiens OX=9606 GN=DDX3X PE=1 SV=3 5.45 1897.8 - 944859 - - - -0.5357 - 2.843 0.519 - 390.9 1 2 1 -0.0007 10 0 0 0 5.89E+07 5.22E+07 - - - 5.7906 0.9968 221125_WJC_METTL3_EV_vs_WT_F08.08724.08724.4 1.23E-05 13/72 K.LSSAENDR[166.11]DILR[166.11]R[166.11].E "sp|Q15643|TRIPB_HUMAN,tr|H0YJ97|H0YJ97_HUMAN" 2 1573.8315 1.1 113675 8724 4 1573.828549 394.4651 Thyroid receptor-interacting protein 11 OS=Homo sapiens OX=9606 GN=TRIP11 PE=1 SV=3 6.12 1898 - 3.49E+06 - - - -1.8604 - 2.311 0.315 - 156.6 1 2 1 -0.0029 13 0 0 0 1.63E+08 1.49E+08 - - - 2.2775 0.9999 221125_WJC_METTL3_EV_vs_WT_F08.08726.08726.3 2.87E-05 16/52 K.K[136.11]GPGEVAGTVTGQK[136.11].R "sp|Q86U44|MTA70_HUMAN,tr|F5H6D8|F5H6D8_HUMAN,tr|H0YFV6|H0YFV6_HUMAN,tr|B4DTN4|B4DTN4_HUMAN" 4 1343.738 0 113676 8726 3 1343.733311 448.9199 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 8.59 1898.2 - 1.97E+06 - - - -3.4739 - 2.799 0.498 - 469.1 1 2 0 -0.0047 14 0 0 0 2.84E+05 1.64E+08 - - - 6.8262 0.836 221125_WJC_METTL3_EV_vs_WT_F08.08728.08728.2 0.0027 16-Aug P.SSAGSVSPR.S sp|P13646|K1C13_HUMAN 1 846.4195 5.78 113677 8728 2 846.417143 424.217 "Keratin, type I cytoskeletal 13 OS=Homo sapiens OX=9606 GN=KRT13 PE=1 SV=4" 9.47 1898.4 - 3.31E+06 - - - -2.8378 - 1.41 0.34 - 221.2 1 1 0 -0.0024 9 0 0 0 1.33E+08 2.30E+07 - - - 2.5455 0.9997 221125_WJC_METTL3_EV_vs_WT_F08.08730.08730.3 1.66E-05 Dec-48 R.ASNGDAWVEAHGK[136.11].L "sp|P38646|GRP75_HUMAN,tr|H0Y8K0|H0Y8K0_HUMAN,tr|A0A7I2V2S7|A0A7I2V2S7_HUMAN,tr|A0A7I2V2G2|A0A7I2V2G2_HUMAN,tr|A0A3B3ITI4|A0A3B3ITI4_HUMAN,tr|A0A7I2V3F7|A0A7I2V3F7_HUMAN,tr|A0A7I2YQB2|A0A7I2YQB2_HUMAN,tr|D6RCD7|D6RCD7_HUMAN" 8 1348.6251 0.6 113679 8730 3 1348.61959 450.549 "Stress-70 protein, mitochondrial OS=Homo sapiens OX=9606 GN=HSPA9 PE=1 SV=2" 5.32 1898.6 - 1.75E+06 - - - -4.1064 - 2.282 0.494 - 217.7 1 2 0 -0.0055 13 0 0 0 5.52E+07 9.15E+07 - - - 6.283 0.9947 221125_WJC_METTL3_EV_vs_WT_F08.08733.08733.4 0.00438 13/72 K.LSSAENDRDILRR.E "sp|Q15643|TRIPB_HUMAN,tr|H0YJ97|H0YJ97_HUMAN" 2 1543.8067 1.09 113680 8733 4 1543.803326 386.9589 Thyroid receptor-interacting protein 11 OS=Homo sapiens OX=9606 GN=TRIP11 PE=1 SV=3 6.12 1899 - 4.91E+06 - - - -2.1641 - 2.342 0.299 - 170.7 1 2 1 -0.0033 13 0 0 0 1.63E+08 1.49E+08 - - - 2.1431 0.9997 221125_WJC_METTL3_EV_vs_WT_F08.08736.08736.2 0.000113 28-Nov K.SVSIQEEQSAPSSEK[136.11].G "sp|Q86XZ4|SPAS2_HUMAN,tr|F8VS10|F8VS10_HUMAN" 2 1612.7672 2.85 113682 8736 2 1612.763183 807.3909 Spermatogenesis-associated serine-rich protein 2 OS=Homo sapiens OX=9606 GN=SPATS2 PE=1 SV=1 4.25 1899.3 - 393710 - - - -2.4659 - 2.282 0.548 - 178.4 1 2 0 -0.004 15 0 0 0 3.11E+07 1.09E+07 - - - 5.1157 0.9555 221125_WJC_METTL3_EV_vs_WT_F08.08737.08737.3 0.787 Nov-36 R.DR[166.11]EEALHQFR[166.11].S "sp|O00571|DDX3X_HUMAN,sp|O15523|DDX3Y_HUMAN,tr|A0A2R8YFR4|A0A2R8YFR4_HUMAN,tr|A0A2R8YCW1|A0A2R8YCW1_HUMAN,tr|A0A2R8YDH3|A0A2R8YDH3_HUMAN,tr|A0A2R8YDT5|A0A2R8YDT5_HUMAN,tr|A0A2R8Y645|A0A2R8Y645_HUMAN,tr|A0A2R8YF78|A0A2R8YF78_HUMAN,tr|A0A0D9SFB3|A0A0D9SFB3_HUMAN,tr|A0A2R8YFS5|A0A2R8YFS5_HUMAN,tr|A0A0D9SF53|A0A0D9SF53_HUMAN,tr|A0A087WVZ1|A0A087WVZ1_HUMAN,tr|A0A0J9YVQ7|A0A0J9YVQ7_HUMAN,tr|A0A2R8Y5G6|A0A2R8Y5G6_HUMAN,tr|A0A2R8Y7T2|A0A2R8Y7T2_HUMAN,tr|A0A0D9SG12|A0A0D9SG12_HUMAN,tr|F6S8Q4|F6S8Q4_HUMAN,tr|A0A2U3TZJ9|A0A2U3TZJ9_HUMAN,tr|A0A2R8Y4A4|A0A2R8Y4A4_HUMAN" 19 1319.6485 1.19 113683 8737 3 1319.64556 440.8901 ATP-dependent RNA helicase DDX3X OS=Homo sapiens OX=9606 GN=DDX3X PE=1 SV=3 5.45 1899.4 - 2.74E+07 - - - -2.2559 - 1.646 0.205 - 119.6 1 2 1 -0.003 10 0 0 0 9.57E+08 8.03E+08 - - - 2.2801 0.9999 221125_WJC_METTL3_EV_vs_WT_F08.08742.08742.3 9.11E-06 Dec-52 R.NIDEQPKPLTDSQR.V "sp|Q9UL18|AGO1_HUMAN,tr|A0A6I8PTZ8|A0A6I8PTZ8_HUMAN,tr|Q5TA58|Q5TA58_HUMAN" 3 1639.8166 8.63 113685 8742 3 1639.813586 547.6128 Protein argonaute-1 OS=Homo sapiens OX=9606 GN=AGO1 PE=1 SV=3 4.56 1900 - 781745 - - - -1.8154 - 2.178 0.434 - 162.1 1 2 0 -0.003 14 0 0 0 1.22E+07 1.42E+06 - - - 5.4465 0.9998 221125_WJC_METTL3_EV_vs_WT_F08.08751.08751.3 2.40E-05 Dec-40 K.GIPHLVTHDAR.T "sp|P62701|RS4X_HUMAN,sp|P22090|RS4Y1_HUMAN,sp|Q8TD47|RS4Y2_HUMAN,tr|C9JEH7|C9JEH7_HUMAN" 4 1214.652 0.77 113689 8751 3 1214.647871 405.8913 "40S ribosomal protein S4, X isoform OS=Homo sapiens OX=9606 GN=RPS4X PE=1 SV=2" 6.92 1901 - 2.81E+06 - - - -3.4026 - 2.372 0.445 - 217.5 1 2 0 -0.0041 11 0 0 0 2.01E+08 2.62E+08 - - - 5.9539 1 221125_WJC_METTL3_EV_vs_WT_F08.08753.08753.3 9.92E-05 Dec-44 K.K[136.11]GESQTDIEITR[166.11].E "sp|P49368|TCPG_HUMAN,tr|B4DUR8|B4DUR8_HUMAN" 2 1393.7168 0.26 113691 8753 3 1393.716882 465.5795 T-complex protein 1 subunit gamma OS=Homo sapiens OX=9606 GN=CCT3 PE=1 SV=4 4.68 1901.2 - 2.26E+07 - - - 0.0639 - 2.391 0.455 - 300 1 2 0 0.0001 12 0 0 0 3.35E+08 1.29E+09 - - - 6.029 0.9999 221125_WJC_METTL3_EV_vs_WT_F08.08754.08754.3 1.71E-05 13/48 R.ASNGDAWVEAHGK.L "sp|P38646|GRP75_HUMAN,tr|H0Y8K0|H0Y8K0_HUMAN,tr|A0A7I2V2S7|A0A7I2V2S7_HUMAN,tr|A0A7I2V2G2|A0A7I2V2G2_HUMAN,tr|A0A3B3ITI4|A0A3B3ITI4_HUMAN,tr|A0A7I2V3F7|A0A7I2V3F7_HUMAN,tr|A0A7I2YQB2|A0A7I2YQB2_HUMAN,tr|D6RCD7|D6RCD7_HUMAN" 8 1340.6109 0.65 113692 8754 3 1340.612297 447.8776 "Stress-70 protein, mitochondrial OS=Homo sapiens OX=9606 GN=HSPA9 PE=1 SV=2" 5.32 1901.3 - 1.91E+06 - - - 1.0212 - 2.453 0.451 - 245.9 1 2 0 0.0014 13 0 0 0 5.95E+07 9.21E+07 - - - 6.0007 1 221125_WJC_METTL3_EV_vs_WT_F08.08759.08759.2 5.77E-06 18/22 K.K[136.11]GESQTDIEITR[166.11].E "sp|P49368|TCPG_HUMAN,tr|B4DUR8|B4DUR8_HUMAN" 2 1393.7168 0.22 113695 8759 2 1393.716926 697.8657 T-complex protein 1 subunit gamma OS=Homo sapiens OX=9606 GN=CCT3 PE=1 SV=4 4.68 1901.9 - 5.70E+06 - - - 0.0954 - 3.187 0.601 - 921.6 1 2 0 0.0001 12 0 0 0 4.74E+07 2.11E+08 - - - 6.5297 0.998 221125_WJC_METTL3_EV_vs_WT_F08.08761.08761.3 0.0157 Sep-44 K.KGESQTDIEITR.E "sp|P49368|TCPG_HUMAN,tr|B4DUR8|B4DUR8_HUMAN" 2 1375.6943 0.26 113697 8761 3 1375.694085 459.5721 T-complex protein 1 subunit gamma OS=Homo sapiens OX=9606 GN=CCT3 PE=1 SV=4 4.68 1902.1 - 8.85E+06 - - - -0.173 - 1.895 0.226 - 119.1 1 2 0 -0.0002 12 0 0 0 3.35E+08 1.29E+09 - - - 2.8314 0.9997 221125_WJC_METTL3_EV_vs_WT_F08.08766.08766.3 0.000207 15/36 K.EEVKLETHIR.V sp|Q9NZI8|IF2B1_HUMAN 1 1252.6776 1.47 113700 8766 3 1252.675916 418.5665 Insulin-like growth factor 2 mRNA-binding protein 1 OS=Homo sapiens OX=9606 GN=IGF2BP1 PE=1 SV=2 5.5 1902.8 - 2.37E+06 - - - -1.3052 - 2.713 0.392 - 414.2 1 2 1 -0.0016 10 0 0 0 2.14E+08 1.46E+08 - - - 5.8247 0.999 221125_WJC_METTL3_EV_vs_WT_F08.08767.08767.3 0.0191 Dec-36 K.EEVK[136.11]LETHIR[166.11].V sp|Q9NZI8|IF2B1_HUMAN 1 1270.7 1.47 113701 8767 3 1270.698004 424.574 Insulin-like growth factor 2 mRNA-binding protein 1 OS=Homo sapiens OX=9606 GN=IGF2BP1 PE=1 SV=2 5.5 1902.8 - 2.59E+06 - - - -1.5873 - 2.333 0.339 - 195.7 1 2 1 -0.002 10 0 0 0 2.14E+08 1.46E+08 - - - 4.793 1 221125_WJC_METTL3_EV_vs_WT_F08.08769.08769.3 5.71E-06 17/52 K.TAEEENPEHVEIQK.M sp|O00566|MPP10_HUMAN 1 1651.7689 2 113703 8769 3 1651.766158 551.5969 U3 small nucleolar ribonucleoprotein protein MPP10 OS=Homo sapiens OX=9606 GN=MPHOSPH10 PE=1 SV=2 4.32 1903 - 1.15E+06 - - - -1.6867 - 2.494 0.546 - 257.4 1 2 0 -0.0028 14 0 0 0 1.55E+08 7.77E+07 - - - 7.0553 1 221125_WJC_METTL3_EV_vs_WT_F08.08774.08774.3 8.68E-06 15/40 K.GIPHLVTHDAR[166.11].T "sp|P62701|RS4X_HUMAN,sp|P22090|RS4Y1_HUMAN,sp|Q8TD47|RS4Y2_HUMAN,tr|C9JEH7|C9JEH7_HUMAN" 4 1224.6603 0.77 113706 8774 3 1224.658876 409.2274 "40S ribosomal protein S4, X isoform OS=Homo sapiens OX=9606 GN=RPS4X PE=1 SV=2" 6.92 1903.6 - 4.16E+06 - - - -1.1415 - 2.48 0.542 - 324.6 1 2 0 -0.0014 11 0 0 0 2.03E+08 2.64E+08 - - - 7.1626 1 221125_WJC_METTL3_EV_vs_WT_F08.08775.08775.2 0.000139 19/22 K.KGESQTDIEITR.E "sp|P49368|TCPG_HUMAN,tr|B4DUR8|B4DUR8_HUMAN" 2 1375.6943 0.22 113707 8775 2 1375.691367 688.8544 T-complex protein 1 subunit gamma OS=Homo sapiens OX=9606 GN=CCT3 PE=1 SV=4 4.68 1903.8 - 1.63E+06 - - - -2.1487 - 3.266 0.57 - 1028 1 2 0 -0.003 12 0 0 0 4.74E+07 2.11E+08 - - - 6.3643 0.9908 221125_WJC_METTL3_EV_vs_WT_F08.08776.08776.3 1.00E-09 19/68 S.LVSGLNSSASEPAK[136.11]EPAK[136.11].K "sp|Q86U44|MTA70_HUMAN,tr|F5H6D8|F5H6D8_HUMAN,tr|H0YFV6|H0YFV6_HUMAN,tr|B4DTN4|B4DTN4_HUMAN" 4 1799.96 0 113708 8776 3 1799.956518 600.9939 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 6.14 1903.8 - 3.20E+06 - - - -1.9306 - 2.923 0.614 - 272.1 1 1 1 -0.0035 18 0 0 0 1.87E+05 1.07E+08 - - - 8.0554 1 221125_WJC_METTL3_EV_vs_WT_F08.08788.08788.2 7.42E-06 14/26 K.K[136.11]GPGEVAGTVTGQK[136.11].R "sp|Q86U44|MTA70_HUMAN,tr|F5H6D8|F5H6D8_HUMAN,tr|H0YFV6|H0YFV6_HUMAN,tr|B4DTN4|B4DTN4_HUMAN" 4 1343.738 0.001 113716 8788 2 1343.734533 672.8763 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 8.59 1905.3 - 581560 - - - -2.5645 - 2.871 0.557 - 523.9 1 2 0 -0.0034 14 0 0 0 0.00E+00 5.51E+07 - - - 5.8005 1 221125_WJC_METTL3_EV_vs_WT_F08.08792.08792.2 5.54E-11 17/30 R.SSEGSLGGQNSGIGGR[166.11].S "sp|Q9UGP4|LIMD1_HUMAN,tr|C9JRJ5|C9JRJ5_HUMAN" 2 1471.6891 0.44 113720 8792 2 1471.688142 736.8518 LIM domain-containing protein 1 OS=Homo sapiens OX=9606 GN=LIMD1 PE=1 SV=1 5.72 1905.8 - 536955 - - - -0.6292 - 3.097 0.665 - 745.7 1 2 0 -0.0009 16 0 0 0 3.69E+06 8.34E+06 - - - 6.7316 0.9944 221125_WJC_METTL3_EV_vs_WT_F08.08796.08796.2 0.0208 22-Oct K.NLKPNPNWNQGK.T "sp|Q6W2J9|BCOR_HUMAN,tr|H7BZ37|H7BZ37_HUMAN,tr|A1A564|A1A564_HUMAN,tr|H7C2V9|H7C2V9_HUMAN,tr|H7BYY2|H7BYY2_HUMAN,tr|H7C231|H7C231_HUMAN" 6 1408.7211 2.59 113722 8796 2 1408.719132 705.3678 BCL-6 corepressor OS=Homo sapiens OX=9606 GN=BCOR PE=1 SV=1 10 1906.3 - 454548 - - - -1.4304 - 1.225 0.235 - 195.6 1 2 0 -0.002 12 0 0 0 1.48E+07 5.71E+06 - - - 1.31 0.9997 221125_WJC_METTL3_EV_vs_WT_F08.08800.08800.3 0.081 Dec-52 K.SINQQSGAHVELQR.N sp|Q96I24|FUBP3_HUMAN 1 1565.791 2.44 113724 8800 3 1565.790405 522.9376 Far upstream element-binding protein 3 OS=Homo sapiens OX=9606 GN=FUBP3 PE=1 SV=2 6.47 1906.9 - 1.23E+06 - - - -0.3909 - 2.292 0.307 - 132.8 1 2 0 -0.0006 14 0 0 0 1.88E+08 7.72E+07 - - - 4.1668 0.9928 221125_WJC_METTL3_EV_vs_WT_F08.08805.08805.2 1.30E-05 18-Sep K.EEVK[136.11]LETHIR[166.11].V sp|Q9NZI8|IF2B1_HUMAN 1 1270.7 2.66 113729 8805 2 1270.696434 636.3573 Insulin-like growth factor 2 mRNA-binding protein 1 OS=Homo sapiens OX=9606 GN=IGF2BP1 PE=1 SV=2 5.5 1907.5 - 482394 - - - -2.8229 - 1.916 0.473 - 319.7 1 2 1 -0.0036 10 0 0 0 6.72E+06 2.52E+06 - - - 4.3485 0.9999 221125_WJC_METTL3_EV_vs_WT_F08.08819.08819.3 0.00162 Dec-36 K.KDMEIAELKK.N "sp|Q15643|TRIPB_HUMAN,tr|H0YJ97|H0YJ97_HUMAN" 2 1203.6533 1.37 113737 8819 3 1203.652261 402.225 Thyroid receptor-interacting protein 11 OS=Homo sapiens OX=9606 GN=TRIP11 PE=1 SV=3 6.18 1909.3 - 1.13E+06 - - - -0.8715 - 2.109 0.404 - 206.1 1 2 0 -0.001 10 0 0 0 1.35E+07 9.84E+06 - - - 5.2232 0.9998 221125_WJC_METTL3_EV_vs_WT_F08.08820.08820.3 5.58E-05 Dec-44 R.GSGEQDWVNRPK.T sp|Q7Z5L9|I2BP2_HUMAN 1 1371.6531 0.73 113738 8820 3 1371.651385 458.225 Interferon regulatory factor 2-binding protein 2 OS=Homo sapiens OX=9606 GN=IRF2BP2 PE=1 SV=2 6.07 1909.3 - 9.25E+06 - - - -1.27 - 2.063 0.362 - 186.2 1 2 0 -0.0017 12 0 0 0 2.46E+08 3.36E+08 - - - 4.5827 0.9996 221125_WJC_METTL3_EV_vs_WT_F08.08827.08827.2 0.000483 26-Jul K.TAEEENPEHVEIQK[136.11].M sp|O00566|MPP10_HUMAN 1 1659.7831 3.26 113745 8827 2 1659.781895 830.8988 U3 small nucleolar ribonucleoprotein protein MPP10 OS=Homo sapiens OX=9606 GN=MPHOSPH10 PE=1 SV=2 4.32 1910.2 - 205696 - - - -0.7525 - 1.556 0.442 - 123.4 1 2 0 -0.0012 14 0 0 0 6.20E+06 1.90E+06 - - - 3.4147 1 221125_WJC_METTL3_EV_vs_WT_F08.08833.08833.3 6.14E-08 13/56 R.ISEAC[160.03]SLAQQSGDHR[166.11].L "sp|P52948|NUP98_HUMAN,tr|H7C3P6|H7C3P6_HUMAN" 2 1667.7561 1.7 113749 8833 3 1667.751762 556.926 Nuclear pore complex protein Nup98-Nup96 OS=Homo sapiens OX=9606 GN=NUP98 PE=1 SV=4 5.32 1911 - 864525 - - - -2.6023 - 2.983 0.554 - 179.6 1 2 0 -0.0043 15 0 0 0 2.71E+07 1.60E+07 - - - 7.5672 0.9977 221125_WJC_METTL3_EV_vs_WT_F08.08834.08834.3 0.00794 Nov-52 K.LIQESDQHLK[136.11]DVEK[136.11].L "sp|O14776|TCRG1_HUMAN,tr|A0A7P0T8N8|A0A7P0T8N8_HUMAN" 2 1696.8967 0.6 113750 8834 3 1696.898485 566.6395 Transcription elongation regulator 1 OS=Homo sapiens OX=9606 GN=TCERG1 PE=1 SV=2 4.75 1911.1 - 595530 - - - 1.0725 - 1.949 0.323 - 126 1 2 1 0.0018 14 0 0 0 4.96E+06 8.25E+06 - - - 3.914 0.9999 221125_WJC_METTL3_EV_vs_WT_F08.08836.08836.3 1.46E-07 Dec-56 R.GR[166.11]GTGEAEEEYVGPR[166.11].L "sp|Q13895|BYST_HUMAN,tr|F8WBL2|F8WBL2_HUMAN" 2 1625.7549 0.76 113752 8836 3 1625.75441 542.9256 Bystin OS=Homo sapiens OX=9606 GN=BYSL PE=1 SV=3 4.49 1911.4 - 498665 - - - -0.2725 - 2.696 0.499 - 232.4 1 2 1 -0.0004 15 0 0 0 5.94E+06 7.77E+06 - - - 6.6911 1 221125_WJC_METTL3_EV_vs_WT_F08.08837.08837.2 9.96E-07 13/26 K.TAEEENPEHVEIQK.M sp|O00566|MPP10_HUMAN 1 1651.7689 3.26 113753 8837 2 1651.771917 826.8917 U3 small nucleolar ribonucleoprotein protein MPP10 OS=Homo sapiens OX=9606 GN=MPHOSPH10 PE=1 SV=2 4.32 1911.5 - 304993 - - - 1.7999 - 2.79 0.624 - 592.2 1 2 0 0.003 14 0 0 0 6.20E+06 1.90E+06 - - - 6.2237 0.9993 221125_WJC_METTL3_EV_vs_WT_F08.08843.08843.3 0.00304 Sep-52 R.VLEENQEHYHIVQK[136.11].F sp|P57740|NU107_HUMAN 1 1772.8937 1.82 113757 8843 3 1772.894148 591.9718 Nuclear pore complex protein Nup107 OS=Homo sapiens OX=9606 GN=NUP107 PE=1 SV=1 5.32 1912.2 - 425401 - - - 0.2538 - 1.651 0.332 - 85.6 1 2 0 0.0004 14 0 0 0 1.25E+07 6.87E+06 - - - 3.5738 0.9996 221125_WJC_METTL3_EV_vs_WT_F08.08848.08848.3 0.00363 13/40 K.VSNRFSGVPDR.F "sp|A0A075B6R9|KVD24_HUMAN,sp|A0A075B6S2|KVD29_HUMAN,sp|A0A0A0MRZ7|KVD26_HUMAN" 3 1232.6262 126.75 113760 8848 3 1232.626496 411.8827 Probable non-functional immunoglobulin kappa variable 2D-24 OS=Homo sapiens OX=9606 GN=IGKV2D-24 PE=1 SV=1 9.57 1912.8 - 977892 - - - 0.2531 - 2.128 0.419 - 321.4 1 2 1 0.0003 11 0 0 0 1.50E+07 1.18E+05 - - - 5.3567 0.8767 221125_WJC_METTL3_EV_vs_WT_F08.08852.08852.3 0.00773 Nov-56 A.TSAGGEESLK[136.11]C[160.03]EDLK[136.11].V "sp|Q9BX74|TM2D1_HUMAN,tr|U3KPS6|U3KPS6_HUMAN,tr|U3KQS3|U3KQS3_HUMAN,tr|J3KPA2|J3KPA2_HUMAN,tr|U3KQ44|U3KQ44_HUMAN,tr|U3KPW4|U3KPW4_HUMAN,tr|U3KQF9|U3KQF9_HUMAN" 7 1638.7742 4.37 113764 8852 3 1638.775337 547.2653 TM2 domain-containing protein 1 OS=Homo sapiens OX=9606 GN=TM2D1 PE=1 SV=1 4.41 1913.3 - 257670 - - - 0.7146 - 2.198 0.328 - 140.4 1 1 1 0.0012 15 0 0 0 2.06E+07 4.72E+06 - - - 4.2516 1 221125_WJC_METTL3_EV_vs_WT_F08.08856.08856.3 3.25E-08 16/52 K.YLANIEQQHGNSGR.N sp|Q9UKX7|NUP50_HUMAN 1 1585.7597 1.34 113766 8856 3 1585.761525 529.5938 Nuclear pore complex protein Nup50 OS=Homo sapiens OX=9606 GN=NUP50 PE=1 SV=2 6.75 1913.9 - 1.69E+06 - - - 1.1401 - 2.735 0.622 - 252.6 1 2 0 0.0018 14 0 0 0 3.88E+07 2.90E+07 - - - 8.148 1 221125_WJC_METTL3_EV_vs_WT_F08.08858.08858.3 1.70E-06 16/52 R.RNSVTPLASPEPTK.K "sp|Q16875|F263_HUMAN,tr|A0A1W2PR17|A0A1W2PR17_HUMAN,tr|Q9H178|Q9H178_HUMAN,tr|Q5W015|Q5W015_HUMAN,tr|Q5VX20|Q5VX20_HUMAN" 5 1495.7995 3.97 113768 8858 3 1495.800796 499.6071 "6-phosphofructo-2-kinase\fructose-2,6-bisphosphatase 3 OS=Homo sapiens OX=9606 GN=PFKFB3 PE=1 SV=1" 8.75 1914.1 - 800455 - - - 0.8952 - 3.207 0.534 - 395.1 1 2 0 0.0013 14 0 0 0 1.70E+07 4.27E+06 - - - 7.5901 1 221125_WJC_METTL3_EV_vs_WT_F08.08859.08859.3 2.17E-08 16/52 R.VLEENQEHYHIVQK.F sp|P57740|NU107_HUMAN 1 1764.8795 1.84 113769 8859 3 1764.882738 589.3004 Nuclear pore complex protein Nup107 OS=Homo sapiens OX=9606 GN=NUP107 PE=1 SV=1 5.32 1914.2 - 719393 - - - 1.8358 - 2.673 0.537 - 191.9 1 2 0 0.0032 14 0 0 0 1.26E+07 6.87E+06 - - - 7.139 1 221125_WJC_METTL3_EV_vs_WT_F08.08861.08861.2 6.82E-08 26-Nov K.NIVQHTTDSSLEEK.Q sp|Q9H501|ESF1_HUMAN 1 1599.774 1.14 113771 8861 2 1599.772116 800.8943 ESF1 homolog OS=Homo sapiens OX=9606 GN=ESF1 PE=1 SV=1 4.65 1914.5 - 161211 - - - -1.1964 - 2.458 0.609 - 316.3 1 2 0 -0.0019 14 0 0 0 3.82E+06 3.36E+06 - - - 5.7953 0.9952 221125_WJC_METTL3_EV_vs_WT_F08.08863.08863.2 0.0785 22-Oct K.QR[166.11]YPDGIISK[136.11]PK[136.11].N sp|Q86U44|MTA70_HUMAN 1 1426.8143 0.001 113772 8863 2 1426.815898 714.4144 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 9.7 1914.7 - 448512 - - - 1.1417 - 2.165 0.338 - 255.7 1 2 1 0.0016 12 0 0 0 0.00E+00 3.36E+09 - - - 3.5693 0.9245 221125_WJC_METTL3_EV_vs_WT_F08.08868.08868.4 0.474 Aug-78 R.VLEENQEHYHIVQK.F sp|P57740|NU107_HUMAN 1 1764.8795 1.24 113776 8868 4 1764.885303 442.2272 Nuclear pore complex protein Nup107 OS=Homo sapiens OX=9606 GN=NUP107 PE=1 SV=1 5.32 1915.1 - 1.08E+06 - - - 3.2892 - 1.511 0.177 - 60.2 1 2 0 0.0058 14 0 0 0 1.77E+07 1.43E+07 - - - 0.9152 0.996 221125_WJC_METTL3_EV_vs_WT_F08.08870.08870.4 0.0601 14/72 R.FVPDKEFSGSDRR.Q "sp|Q13573|SNW1_HUMAN,tr|G3V4X8|G3V4X8_HUMAN" 2 1538.7478 0.94 113778 8870 4 1538.74983 385.6942 SNW domain-containing protein 1 OS=Homo sapiens OX=9606 GN=SNW1 PE=1 SV=1 6.12 1915.3 - 451021 - - - 1.3485 - 2.096 0.296 - 118.4 1 2 1 0.0021 13 0 0 0 3.23E+07 3.43E+07 - - - 2.0762 0.9999 221125_WJC_METTL3_EV_vs_WT_F08.08872.08872.2 1.55E-05 26-Nov K.NIVQHTTDSSLEEK[136.11].Q sp|Q9H501|ESF1_HUMAN 1 1607.7882 1.14 113780 8872 2 1607.786232 804.9014 ESF1 homolog OS=Homo sapiens OX=9606 GN=ESF1 PE=1 SV=1 4.65 1915.6 - 209245 - - - -1.2427 - 2.438 0.532 - 291.4 1 2 0 -0.002 14 0 0 0 3.82E+06 3.36E+06 - - - 5.2061 0.9998 221125_WJC_METTL3_EV_vs_WT_F08.08873.08873.2 2.60E-06 26-Oct R.SQTPNNTVTYESER[166.11].G sp|Q9NVW2|RNF12_HUMAN 1 1634.7412 0.21 113781 8873 2 1634.738229 818.3779 E3 ubiquitin-protein ligase RLIM OS=Homo sapiens OX=9606 GN=RLIM PE=1 SV=3 4.53 1915.7 - 110630 - - - -1.7948 - 2.292 0.594 - 345.4 1 2 0 -0.0029 14 0 0 0 2.06E+05 1.00E+06 - - - 5.5088 0.9988 221125_WJC_METTL3_EV_vs_WT_F08.08874.08874.2 6.69E-06 26-Sep K.YLANIEQQHGNSGR.N sp|Q9UKX7|NUP50_HUMAN 1 1585.7597 6.4 113782 8874 2 1585.75644 793.8871 Nuclear pore complex protein Nup50 OS=Homo sapiens OX=9606 GN=NUP50 PE=1 SV=2 6.75 1915.8 - 99961.7 - - - -2.0665 - 1.927 0.31 - 254.1 1 2 0 -0.0033 14 0 0 0 2.49E+06 3.89E+05 - - - 2.9757 0.9998 221125_WJC_METTL3_EV_vs_WT_F08.08876.08876.3 2.72E-07 14/44 K.QR[166.11]YPDGIISK[136.11]PK[136.11].N sp|Q86U44|MTA70_HUMAN 1 1426.8143 0 113783 8876 3 1426.817142 476.612 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 9.7 1916.1 - 9.81E+06 - - - 2.0136 - 2.196 0.579 - 324.6 1 2 1 0.0029 12 0 0 0 1.03E+08 5.44E+10 - - - 7.1749 0.9993 221125_WJC_METTL3_EV_vs_WT_F08.08879.08879.3 0.000239 Nov-52 K.NIVQHTTDSSLEEK[136.11].Q sp|Q9H501|ESF1_HUMAN 1 1607.7882 1.46 113785 8879 3 1607.793795 536.9367 ESF1 homolog OS=Homo sapiens OX=9606 GN=ESF1 PE=1 SV=1 4.65 1916.3 - 1.36E+06 - - - 3.4613 - 2.115 0.391 - 95.3 1 2 0 0.0056 14 0 0 0 2.12E+07 1.46E+07 - - - 4.8884 0.9839 221125_WJC_METTL3_EV_vs_WT_F08.08882.08882.2 5.87E-06 26-Jul R.HGSGSGQSSSYSPY.G "sp|Q86YZ3|HORN_HUMAN,sp|Q86YZ3|HORN_HUMAN" 2 1399.564 - 113788 8882 2 1399.566336 700.7893 Hornerin OS=Homo sapiens OX=9606 GN=HRNR PE=1 SV=2 6.74 1916.7 - 318703 - - - 1.6427 - 1.638 0.577 - 78.7 1 1 0 0.0023 14 0 0 0 - - - - - 4.5404 1 221125_WJC_METTL3_EV_vs_WT_F08.08883.08883.3 5.95E-08 20/92 R.LR[166.11]GDAAAGPGPGAGAGAAAEPEPR[166.11].R "sp|Q6DKJ4|NXN_HUMAN,tr|A0A0G2JQK5|A0A0G2JQK5_HUMAN" 2 2135.0623 0.85 113789 8883 3 2135.066953 712.6947 Nucleoredoxin OS=Homo sapiens OX=9606 GN=NXN PE=1 SV=2 4.68 1916.8 - 223901 - - - 2.1943 - 3.638 0.624 - 420.5 1 2 1 0.0047 24 0 0 0 2.83E+06 3.34E+06 - - - 8.4952 0.9623 221125_WJC_METTL3_EV_vs_WT_F08.08884.08884.3 0.0471 Jun-36 K.HTFYGIESHR.C sp|Q9NV66|TYW1_HUMAN 1 1245.5891 1.07 113790 8884 3 1245.593006 416.2036 S-adenosyl-L-methionine-dependent tRNA 4-demethylwyosine synthase TYW1 OS=Homo sapiens OX=9606 GN=TYW1 PE=2 SV=2 6.92 1916.9 - 173903 - - - 3.16 - 1.474 0.217 - 53.2 3 2 0 0.0039 10 0 0 0 1.84E+06 1.72E+06 - - - 1.8705 0.9996 221125_WJC_METTL3_EV_vs_WT_F08.08885.08885.3 5.07E-08 15/76 R.VPVASPSAHNISSSGGAPDR[166.11].T "sp|Q7KZI7|MARK2_HUMAN,tr|A0A0A0MRU9|A0A0A0MRU9_HUMAN,tr|E7ETY4|E7ETY4_HUMAN,tr|A0A7I2YQF3|A0A7I2YQF3_HUMAN,tr|A0A7I2YQR3|A0A7I2YQR3_HUMAN,tr|E9PC69|E9PC69_HUMAN" 6 1914.9423 1.02 113791 8885 3 1914.950038 639.3214 Serine\threonine-protein kinase MARK2 OS=Homo sapiens OX=9606 GN=MARK2 PE=1 SV=2 6.71 1917.1 - 126864 - - - 4.0288 - 2.536 0.453 - 223.1 1 2 0 0.0077 20 0 0 0 2.68E+07 2.62E+07 - - - 5.846 0.9997 221125_WJC_METTL3_EV_vs_WT_F08.08887.08887.2 0.00195 26-Aug R.RNSVTPLASPEPTK.K "sp|Q16875|F263_HUMAN,tr|A0A1W2PR17|A0A1W2PR17_HUMAN,tr|Q9H178|Q9H178_HUMAN,tr|Q5W015|Q5W015_HUMAN,tr|Q5VX20|Q5VX20_HUMAN" 5 1495.7995 28.84 113793 8887 2 1495.798206 748.907 "6-phosphofructo-2-kinase\fructose-2,6-bisphosphatase 3 OS=Homo sapiens OX=9606 GN=PFKFB3 PE=1 SV=1" 8.75 1917.3 - 120697 - - - -0.8363 - 1.765 0.449 - 128.1 1 2 0 -0.0013 14 0 0 0 1.55E+06 5.38E+04 - - - 3.7827 0.9998 221125_WJC_METTL3_EV_vs_WT_F08.08890.08890.3 1.83E-06 14/36 R.TKYEHELALR.Q sp|P08779|K1C16_HUMAN 1 1258.667 10614.6 113794 8890 3 1258.669286 420.5629 "Keratin, type I cytoskeletal 16 OS=Homo sapiens OX=9606 GN=KRT16 PE=1 SV=4" 6.42 1917.7 - 704395 - - - 1.8273 - 2.4 0.536 - 327.1 1 2 1 0.0023 10 0 0 0 1.48E+09 1.40E+05 - - - 7.072 0.9998 221125_WJC_METTL3_EV_vs_WT_F08.08891.08891.3 1.33E-06 16/56 R.R[166.11]WDQTADQTPGATPK[136.11].K sp|O75533|SF3B1_HUMAN 1 1688.8237 1.12 113795 8891 3 1688.830968 563.9485 Splicing factor 3B subunit 1 OS=Homo sapiens OX=9606 GN=SF3B1 PE=1 SV=3 5.96 1917.9 - 398128 - - - 4.2929 - 3.106 0.499 - 321.4 1 2 0 0.0073 15 0 0 0 9.46E+06 8.43E+06 - - - 7.0586 0.8267 221125_WJC_METTL3_EV_vs_WT_F08.08897.08897.3 0.0143 Aug-48 K.SVK[136.11]EDSNLTLQEK[136.11].K "sp|P46940|IQGA1_HUMAN,tr|H0YLE8|H0YLE8_HUMAN" 2 1505.7908 0.78 113801 8897 3 1505.79765 502.9375 Ras GTPase-activating-like protein IQGAP1 OS=Homo sapiens OX=9606 GN=IQGAP1 PE=1 SV=1 4.68 1918.6 - 371433 - - - 4.5478 - 1.811 0.203 - 76 1 2 1 0.0068 13 0 0 0 1.71E+07 2.20E+07 - - - 2.4115 1 221125_WJC_METTL3_EV_vs_WT_F08.08903.08903.3 1.07E-07 15/56 R.RWDQTADQTPGATPK.K sp|O75533|SF3B1_HUMAN 1 1670.8012 1.11 113805 8903 3 1670.798262 557.941 Splicing factor 3B subunit 1 OS=Homo sapiens OX=9606 GN=SF3B1 PE=1 SV=3 5.96 1919.3 - 817625 - - - -1.7872 - 2.832 0.494 - 361 1 2 0 -0.003 15 0 0 0 9.37E+06 8.43E+06 - - - 6.7631 0.9991 221125_WJC_METTL3_EV_vs_WT_F08.08906.08906.4 2.23E-05 Dec-72 R.MDYEDDRLRDGER.C "sp|P43243|MATR3_HUMAN,tr|A8MXP9|A8MXP9_HUMAN,tr|D6R991|D6R991_HUMAN,tr|A0A0R4J2E8|A0A0R4J2E8_HUMAN,tr|D6REM6|D6REM6_HUMAN" 5 1668.7162 1.23 113808 8906 4 1668.720067 418.1863 Matrin-3 OS=Homo sapiens OX=9606 GN=MATR3 PE=1 SV=2 4.23 1919.7 - 409174 - - - 2.3191 - 2 0.419 - 168.6 1 2 2 0.0039 13 0 0 0 1.22E+07 9.96E+06 - - - 3.1289 1 221125_WJC_METTL3_EV_vs_WT_F08.08908.08908.3 3.55E-13 21/76 R.VPVASPSAHNISSSGGAPDR.T "sp|Q7KZI7|MARK2_HUMAN,tr|A0A0A0MRU9|A0A0A0MRU9_HUMAN,tr|E7ETY4|E7ETY4_HUMAN,tr|A0A7I2YQF3|A0A7I2YQF3_HUMAN,tr|A0A7I2YQR3|A0A7I2YQR3_HUMAN,tr|E9PC69|E9PC69_HUMAN" 6 1904.9341 1.02 113810 8908 3 1904.944385 635.9853 Serine\threonine-protein kinase MARK2 OS=Homo sapiens OX=9606 GN=MARK2 PE=1 SV=2 6.71 1919.9 - 315990 - - - 5.4238 - 4.077 0.69 - 520.2 1 2 0 0.0103 20 0 0 0 2.68E+07 2.62E+07 - - - 9.6394 0.9993 221125_WJC_METTL3_EV_vs_WT_F08.08909.08909.3 0.0127 Oct-52 R.R[166.11]NSVTPLASPEPTK[136.11].K "sp|Q16875|F263_HUMAN,tr|A0A1W2PR17|A0A1W2PR17_HUMAN,tr|Q9H178|Q9H178_HUMAN,tr|Q5W015|Q5W015_HUMAN,tr|Q5VX20|Q5VX20_HUMAN" 5 1513.8219 3.97 113811 8909 3 1513.819782 505.6146 "6-phosphofructo-2-kinase\fructose-2,6-bisphosphatase 3 OS=Homo sapiens OX=9606 GN=PFKFB3 PE=1 SV=1" 8.75 1920.1 - 284758 - - - -1.4169 - 2.015 0.3 - 122.8 1 2 0 -0.0021 14 0 0 0 1.70E+07 4.27E+06 - - - 3.746 1 221125_WJC_METTL3_EV_vs_WT_F08.08910.08910.3 1.18E-05 Oct-52 R.DTSSC[160.03]MTPYSHSPR.T sp|Q15699|ALX1_HUMAN 1 1624.661 1.01 113812 8910 3 1624.66165 542.5609 ALX homeobox protein 1 OS=Homo sapiens OX=9606 GN=ALX1 PE=1 SV=2 6.73 1920.2 - 219158 - - - 0.4056 - 2.379 0.585 - 154.9 1 2 0 0.0007 14 0 0 0 3.48E+06 3.45E+06 - - - 7.3652 0.9631 221125_WJC_METTL3_EV_vs_WT_F08.08914.08914.3 0.00928 Oct-44 K.EHHFGSSGMTLH.E "sp|Q9Y2W1|TR150_HUMAN,tr|A0A3B3ITZ9|A0A3B3ITZ9_HUMAN" 2 1338.5775 - 113814 8914 3 1338.578714 447.1998 Thyroid hormone receptor-associated protein 3 OS=Homo sapiens OX=9606 GN=THRAP3 PE=1 SV=2 6.27 1920.8 - 1.75E+06 - - - 0.8927 - 1.798 0.354 - 118.7 1 1 0 0.0012 12 0 0 0 - - - - - 4.1126 1 221125_WJC_METTL3_EV_vs_WT_F08.08919.08919.2 3.90E-07 18-Nov R.TKYEHELALR.Q sp|P08779|K1C16_HUMAN 1 1258.667 999 113819 8919 2 1258.669644 630.3408 "Keratin, type I cytoskeletal 16 OS=Homo sapiens OX=9606 GN=KRT16 PE=1 SV=4" 6.42 1921.3 - 418779 - - - 2.1118 - 2.233 0.607 - 399.3 1 2 1 0.0027 10 0 0 0 6.80E+07 0.00E+00 - - - 5.7659 0.9932 221125_WJC_METTL3_EV_vs_WT_F08.08921.08921.2 4.46E-05 24-Sep K.SVK[136.11]EDSNLTLQEK[136.11].K "sp|P46940|IQGA1_HUMAN,tr|H0YLE8|H0YLE8_HUMAN" 2 1505.7908 0.77 113821 8921 2 1505.794913 753.9027 Ras GTPase-activating-like protein IQGAP1 OS=Homo sapiens OX=9606 GN=IQGAP1 PE=1 SV=1 4.68 1921.5 - 186177 - - - 2.7301 - 2.208 0.45 - 141.2 1 2 1 0.0041 13 0 0 0 1.93E+06 2.51E+06 - - - 4.3963 1 221125_WJC_METTL3_EV_vs_WT_F08.08928.08928.3 1.38E-05 Dec-48 R.R[166.11]GDIIGVQGNPGK[136.11].T "sp|Q15046|SYK_HUMAN,tr|H3BVA8|H3BVA8_HUMAN,tr|J3KRL2|J3KRL2_HUMAN,tr|H3BPV7|H3BPV7_HUMAN" 4 1327.7327 0.72 113826 8928 3 1327.73481 443.5848 Lysine--tRNA ligase OS=Homo sapiens OX=9606 GN=KARS1 PE=1 SV=3 8.75 1922.4 - 696118 - - - 1.5756 - 2.652 0.48 - 227.2 1 2 0 0.0021 13 0 0 0 6.29E+06 8.74E+06 - - - 6.5353 0.9939 221125_WJC_METTL3_EV_vs_WT_F08.08933.08933.3 0.0461 Jun-52 R.K[136.11]DMYNDTLNGSTEK[136.11].R sp|Q96PU8|QKI_HUMAN 1 1630.748 1.16 113831 8933 3 1630.747996 544.5899 Protein quaking OS=Homo sapiens OX=9606 GN=QKI PE=1 SV=1 4.56 1923 - 147181 - - - 0.0276 - 1.202 0.276 - 30.3 1 2 0 0 14 0 0 0 1.12E+07 9.60E+06 - - - 2.1061 0.9988 221125_WJC_METTL3_EV_vs_WT_F08.08934.08934.2 0.0166 28-Jun K.SSQPQAGSQGPQTFR[166.11].Q "sp|Q13356|PPIL2_HUMAN,tr|A0A7P0TA15|A0A7P0TA15_HUMAN,tr|A0A7P0TAH4|A0A7P0TAH4_HUMAN,tr|A0A7P0TB19|A0A7P0TB19_HUMAN,tr|A0A7P0Z4K4|A0A7P0Z4K4_HUMAN,tr|A0A7P0T8E8|A0A7P0T8E8_HUMAN" 6 1584.752 0.04 113832 8934 2 1584.751455 793.3833 RING-type E3 ubiquitin-protein ligase PPIL2 OS=Homo sapiens OX=9606 GN=PPIL2 PE=1 SV=1 9.47 1923.2 - 130357 - - - -0.3458 - 1.368 0.324 - 80.9 1 2 0 -0.0005 15 0 0 0 9.86E+04 2.58E+06 - - - 2.2043 1 221125_WJC_METTL3_EV_vs_WT_F08.08947.08947.3 5.82E-06 18/52 K.C[160.03]GFC[160.03]HVGEEENEAR[166.11].G "sp|Q8IWS0|PHF6_HUMAN,tr|Q5JRC6|Q5JRC6_HUMAN,tr|A0A0D9SGE8|A0A0D9SGE8_HUMAN" 3 1702.6703 1.28 113841 8947 3 1702.668262 568.5641 PHD finger protein 6 OS=Homo sapiens OX=9606 GN=PHF6 PE=1 SV=1 4.48 1924.8 - 931128 - - - -1.211 - 3.447 0.681 - 580.5 1 2 0 -0.0021 14 0 0 0 1.97E+07 1.55E+07 - - - 9.4206 1 221125_WJC_METTL3_EV_vs_WT_F08.08950.08950.3 1.04E-08 15/52 K.C[160.03]GFC[160.03]HVGEEENEAR.G "sp|Q8IWS0|PHF6_HUMAN,tr|Q5JRC6|Q5JRC6_HUMAN,tr|A0A0D9SGE8|A0A0D9SGE8_HUMAN" 3 1692.6621 1.26 113844 8950 3 1692.664453 565.228 PHD finger protein 6 OS=Homo sapiens OX=9606 GN=PHF6 PE=1 SV=1 4.48 1925.1 - 724822 - - - 1.4173 - 2.453 0.704 - 222.2 1 2 0 0.0024 14 0 0 0 1.97E+07 1.57E+07 - - - 8.7729 0.9955 221125_WJC_METTL3_EV_vs_WT_F08.08953.08953.2 0.000299 24-Sep K.SVKEDSNLTLQEK.K "sp|P46940|IQGA1_HUMAN,tr|H0YLE8|H0YLE8_HUMAN" 2 1489.7624 0.77 113847 8953 2 1489.76372 745.8885 Ras GTPase-activating-like protein IQGAP1 OS=Homo sapiens OX=9606 GN=IQGAP1 PE=1 SV=1 4.68 1925.4 - 113007 - - - 0.8847 - 1.972 0.367 - 117.3 1 2 1 0.0013 13 0 0 0 1.93E+06 2.51E+06 - - - 3.494 0.9995 221125_WJC_METTL3_EV_vs_WT_F08.08958.08958.3 0.00378 Oct-40 R.DKPYAC[160.03]DIC[160.03]GK.R sp|Q92785|REQU_HUMAN 1 1325.5744 1.91 113850 8958 3 1325.575319 442.8654 Zinc finger protein ubi-d4 OS=Homo sapiens OX=9606 GN=DPF2 PE=1 SV=2 5.95 1926 - 1.08E+06 - - - 0.6872 - 1.728 0.335 - 183.5 1 2 0 0.0009 11 0 0 0 3.14E+07 1.65E+07 - - - 3.8285 1 221125_WJC_METTL3_EV_vs_WT_F08.08959.08959.3 1.85E-05 17/60 R.SLAEAC[160.03]SDGDVNAVRK.L "sp|Q8IWZ3|ANKH1_HUMAN,tr|E9PDP5|E9PDP5_HUMAN,tr|D6RHC4|D6RHC4_HUMAN" 3 1690.7944 1.31 113851 8959 3 1690.795304 564.6054 Ankyrin repeat and KH domain-containing protein 1 OS=Homo sapiens OX=9606 GN=ANKHD1 PE=1 SV=1 4.56 1926.1 - 1.04E+06 - - - 0.5063 - 3.262 0.406 - 232.4 1 2 0 0.0009 16 0 0 0 1.50E+07 1.14E+07 - - - 6.1 1 221125_WJC_METTL3_EV_vs_WT_F08.08960.08960.3 9.68E-11 15/52 R.KDMYNDTLNGSTEK.R sp|Q96PU8|QKI_HUMAN 1 1614.7196 1.16 113852 8960 3 1614.719153 539.2471 Protein quaking OS=Homo sapiens OX=9606 GN=QKI PE=1 SV=1 4.56 1926.2 - 996067 - - - -0.2465 - 3.179 0.665 - 353.3 1 2 0 -0.0004 14 0 0 0 1.11E+07 9.60E+06 - - - 9.0276 0.9914 221125_WJC_METTL3_EV_vs_WT_F08.08963.08963.2 0.00249 22-Nov K.EHHFGSSGMTLH.E "sp|Q9Y2W1|TR150_HUMAN,tr|A0A3B3ITZ9|A0A3B3ITZ9_HUMAN" 2 1338.5775 - 113855 8963 2 1338.578864 670.296 Thyroid hormone receptor-associated protein 3 OS=Homo sapiens OX=9606 GN=THRAP3 PE=1 SV=2 6.27 1926.5 - 701523 - - - 1.0048 - 2.172 0.537 - 278 1 1 0 0.0013 12 0 0 0 - - - - - 5.0477 1 221125_WJC_METTL3_EV_vs_WT_F08.08968.08968.2 5.87E-07 28-Dec R.NTDQASMPENTVAQK[136.11].L sp|P35580|MYH10_HUMAN 1 1640.7555 0.99 113860 8968 2 1640.758067 821.3851 Myosin-10 OS=Homo sapiens OX=9606 GN=MYH10 PE=1 SV=3 4.37 1927.2 - 282121 - - - 1.5347 - 2.73 0.584 - 373.8 1 2 0 0.0025 15 0 0 0 1.45E+07 1.46E+07 - - - 5.8228 0.9834 221125_WJC_METTL3_EV_vs_WT_F08.08974.08974.3 0.188 Dec-48 K.IQDKEGIPPDQQR.L "sp|P62979|RS27A_HUMAN,sp|P0CG48|UBC_HUMAN,sp|P0CG48|UBC_HUMAN,sp|P0CG48|UBC_HUMAN,sp|P0CG48|UBC_HUMAN,sp|P0CG48|UBC_HUMAN,sp|P0CG48|UBC_HUMAN,sp|P0CG48|UBC_HUMAN,sp|P0CG48|UBC_HUMAN,sp|P0CG48|UBC_HUMAN,sp|P0CG47|UBB_HUMAN,sp|P0CG47|UBB_HUMAN,sp|P0CG47|UBB_HUMAN,sp|P62987|RL40_HUMAN,tr|F5H388|F5H388_HUMAN,tr|F5H388|F5H388_HUMAN,tr|F5GYU3|F5GYU3_HUMAN,tr|F5GYU3|F5GYU3_HUMAN,tr|B4DV12|B4DV12_HUMAN,tr|B4DV12|B4DV12_HUMAN,tr|J3QSA3|J3QSA3_HUMAN,tr|Q5PY61|Q5PY61_HUMAN,tr|Q5PY61|Q5PY61_HUMAN,tr|Q5PY61|Q5PY61_HUMAN,tr|F5H2Z3|F5H2Z3_HUMAN,tr|F5H2Z3|F5H2Z3_HUMAN,tr|M0R2S1|M0R2S1_HUMAN,tr|J3QS39|J3QS39_HUMAN,tr|J3QTR3|J3QTR3_HUMAN,tr|Q96C32|Q96C32_HUMAN,tr|Q96C32|Q96C32_HUMAN,tr|Q96C32|Q96C32_HUMAN,tr|Q96C32|Q96C32_HUMAN,tr|M0R1V7|M0R1V7_HUMAN,tr|F5H747|F5H747_HUMAN,tr|F5H747|F5H747_HUMAN,tr|F5GXK7|F5GXK7_HUMAN,tr|F5GXK7|F5GXK7_HUMAN,tr|M0R1M6|M0R1M6_HUMAN,tr|F5H6Q2|F5H6Q2_HUMAN,tr|F5H6Q2|F5H6Q2_HUMAN,tr|F5GZ39|F5GZ39_HUMAN,tr|J3QKN0|J3QKN0_HUMAN,tr|J3QKN0|J3QKN0_HUMAN,tr|F5H265|F5H265_HUMAN,tr|F5H265|F5H265_HUMAN,tr|A0A2R8Y422|A0A2R8Y422_HUMAN" 47 1522.774 0.25 113864 8974 3 1522.776044 508.5986 Ubiquitin-40S ribosomal protein S27a OS=Homo sapiens OX=9606 GN=RPS27A PE=1 SV=2 4.56 1928 - 974523 - - - 1.362 - 2.002 0.197 - 161.4 1 2 1 0.0021 13 0 0 0 1.99E+07 7.87E+07 - - - 2.6178 0.9997 221125_WJC_METTL3_EV_vs_WT_F08.08979.08979.2 0.00377 20-Oct R.DKPYAC[160.03]DIC[160.03]GK.R sp|Q92785|REQU_HUMAN 1 1325.5744 1.19 113869 8979 2 1325.574694 663.7945 Zinc finger protein ubi-d4 OS=Homo sapiens OX=9606 GN=DPF2 PE=1 SV=2 5.95 1928.5 - 245310 - - - 0.2158 - 1.59 0.476 - 302.3 1 2 0 0.0003 11 0 0 0 4.65E+06 3.91E+06 - - - 3.8112 1 221125_WJC_METTL3_EV_vs_WT_F08.08981.08981.2 7.52E-09 14/32 R.GHAGSVDSIAVDGSGTK.F sp|Q9GZL7|WDR12_HUMAN 1 1556.7431 1.86 113871 8981 2 1556.741661 779.3788 Ribosome biogenesis protein WDR12 OS=Homo sapiens OX=9606 GN=WDR12 PE=1 SV=2 5.21 1928.8 - 143899 - - - -0.9012 - 2.911 0.704 - 385.2 1 2 0 -0.0014 17 0 0 0 1.88E+06 1.02E+06 - - - 6.8673 1 221125_WJC_METTL3_EV_vs_WT_F08.08985.08985.3 1.73E-07 19/60 R.SLAEAC[160.03]SDGDVNAVR[166.11]K[136.11].L "sp|Q8IWZ3|ANKH1_HUMAN,tr|E9PDP5|E9PDP5_HUMAN,tr|D6RHC4|D6RHC4_HUMAN" 3 1708.8169 1.31 113873 8985 3 1708.813065 570.6129 Ankyrin repeat and KH domain-containing protein 1 OS=Homo sapiens OX=9606 GN=ANKHD1 PE=1 SV=1 4.56 1929.2 - 703849 - - - -2.2548 - 3.767 0.587 - 322.5 1 2 0 -0.0039 16 0 0 0 1.50E+07 1.14E+07 - - - 8.4865 1 221125_WJC_METTL3_EV_vs_WT_F08.08986.08986.2 7.96E-09 13/28 R.NTDQASMPENTVAQK.L sp|P35580|MYH10_HUMAN 1 1632.7413 0.99 113874 8986 2 1632.741868 817.378 Myosin-10 OS=Homo sapiens OX=9606 GN=MYH10 PE=1 SV=3 4.37 1929.4 - 752200 - - - 0.3179 - 2.765 0.603 - 436.2 1 2 0 0.0005 15 0 0 0 1.45E+07 1.46E+07 - - - 5.995 0.9999 221125_WJC_METTL3_EV_vs_WT_F08.08990.08990.2 0.000366 Dec-38 K.AADPPAENSSAPEAEQGGAE.- "sp|P67809|YBOX1_HUMAN,tr|H0Y449|H0Y449_HUMAN" 2 1896.7973 - 113878 8990 2 1896.79954 949.4059 Y-box-binding protein 1 OS=Homo sapiens OX=9606 GN=YBX1 PE=1 SV=3 3.7 1929.9 - 208764 - - - 1.1577 - 2.559 0.584 - 304.3 1 2 0 0.0022 20 0 0 0 - - - - - 5.6638 1 221125_WJC_METTL3_EV_vs_WT_F08.08996.08996.2 7.38E-06 15/24 K.GPGEVAGTVTGQK[136.11].R "sp|Q86U44|MTA70_HUMAN,tr|F5H6D8|F5H6D8_HUMAN,tr|H0YFV6|H0YFV6_HUMAN,tr|B4DTN4|B4DTN4_HUMAN" 4 1207.6288 0.001 113882 8996 2 1207.629478 604.8217 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 6 1930.6 - 1.59E+06 - - - 0.5482 - 2.808 0.555 - 980.3 1 2 0 0.0007 13 0 0 0 0.00E+00 4.35E+07 - - - 5.7899 0.9999 221125_WJC_METTL3_EV_vs_WT_F08.08997.08997.3 0.000119 14/40 R.DHPLPEVAHVK[136.11].H "sp|P13073|COX41_HUMAN,tr|Q86WV2|Q86WV2_HUMAN,tr|H3BN72|H3BN72_HUMAN,tr|H3BPG0|H3BPG0_HUMAN,tr|H3BNV9|H3BNV9_HUMAN" 5 1248.6706 1.68 113883 8997 3 1248.673554 417.2308 "Cytochrome c oxidase subunit 4 isoform 1, mitochondrial OS=Homo sapiens OX=9606 GN=COX4I1 PE=1 SV=1" 5.99 1930.7 - 463561 - - - 2.3489 - 2.667 0.47 - 355.2 1 2 0 0.0029 11 0 0 0 8.51E+07 5.06E+07 - - - 6.5659 1 221125_WJC_METTL3_EV_vs_WT_F08.08998.08998.3 2.14E-08 19/68 R.VPAASPSAHSISTATPDR.T "sp|Q9P0L2|MARK1_HUMAN,tr|A0A7I2V550|A0A7I2V550_HUMAN,tr|A0A087X0I6|A0A087X0I6_HUMAN,tr|A0A7I2YQC1|A0A7I2YQC1_HUMAN,tr|B4DIB3|B4DIB3_HUMAN" 5 1763.8802 0.89 113884 8998 3 1763.883034 588.9674 Serine\threonine-protein kinase MARK1 OS=Homo sapiens OX=9606 GN=MARK1 PE=1 SV=2 6.71 1930.8 - 435003 - - - 1.5919 - 3.424 0.583 - 598.8 1 2 0 0.0028 18 0 0 0 1.14E+07 1.29E+07 - - - 8.1039 1 221125_WJC_METTL3_EV_vs_WT_F08.09004.09004.3 3.65E-08 18/64 R.VGEAAHALGNTGHEIGR.Q sp|Q6E0U4|DMKN_HUMAN 1 1687.839 4.04 113888 9004 3 1687.843085 563.6203 Dermokine OS=Homo sapiens OX=9606 GN=DMKN PE=1 SV=3 6 1931.5 - 995336 - - - 2.4025 - 3.524 0.572 - 489.8 1 2 0 0.0041 17 0 0 0 2.05E+07 5.07E+06 - - - 8.0982 0.9997 221125_WJC_METTL3_EV_vs_WT_F08.09007.09007.3 0.00015 Dec-60 R.IQAGEVSQPSK[136.11]EQLEK[136.11].L sp|Q9BRP8|PYM1_HUMAN 1 1785.9443 0.66 113891 9007 3 1785.946267 596.3221 Partner of Y14 and mago OS=Homo sapiens OX=9606 GN=PYM1 PE=1 SV=1 4.79 1931.8 - 355183 - - - 1.0773 - 2.71 0.41 - 153.9 1 2 1 0.0019 16 0 0 0 7.78E+06 1.18E+07 - - - 5.6686 0.9979 221125_WJC_METTL3_EV_vs_WT_F08.09008.09008.3 0.00786 Sep-76 K.AADPPAENSSAPEAEQGGAE.- "sp|P67809|YBOX1_HUMAN,tr|H0Y449|H0Y449_HUMAN" 2 1896.7973 - 113892 9008 3 1896.801861 633.2731 Y-box-binding protein 1 OS=Homo sapiens OX=9606 GN=YBX1 PE=1 SV=3 3.7 1932 - 308138 - - - 2.3814 - 1.644 0.332 - 68.2 1 2 0 0.0045 20 0 0 0 - - - - - 3.4463 1 221125_WJC_METTL3_EV_vs_WT_F08.09015.09015.3 1.99E-06 14/52 K.KEPAASAAAFPSQR.T sp|Q9Y2X9|ZN281_HUMAN 1 1429.7314 1.3 113897 9015 3 1429.731982 477.5844 Zinc finger protein 281 OS=Homo sapiens OX=9606 GN=ZNF281 PE=1 SV=1 8.75 1932.7 - 981976 - - - 0.4232 - 2.231 0.502 - 223.1 1 2 0 0.0006 14 0 0 0 1.73E+07 1.34E+07 - - - 6.2692 1 221125_WJC_METTL3_EV_vs_WT_F08.09019.09019.2 1.14E-05 28-Dec K.VDNSSLTGESEPQTR.S "sp|P05023|AT1A1_HUMAN,sp|P13637|AT1A3_HUMAN,sp|P50993|AT1A2_HUMAN,sp|P20648|ATP4A_HUMAN,tr|A0A0A0MT26|A0A0A0MT26_HUMAN,tr|M0QXF2|M0QXF2_HUMAN,tr|A0A2R8YEY8|A0A2R8YEY8_HUMAN,tr|B1AKY9|B1AKY9_HUMAN,tr|M0R116|M0R116_HUMAN" 9 1618.7435 1.54 113901 9019 2 1618.742287 810.379 Sodium\potassium-transporting ATPase subunit alpha-1 OS=Homo sapiens OX=9606 GN=ATP1A1 PE=1 SV=1 4.14 1933.2 - 179104 - - - -0.7234 - 2.39 0.621 - 484.2 1 2 0 -0.0012 15 0 0 0 6.42E+06 4.15E+06 - - - 5.7695 0.9967 221125_WJC_METTL3_EV_vs_WT_F08.09023.09023.3 0.0214 Nov-44 K.K[136.11]K[136.11]EVPAVPETLK[136.11].K sp|P18124|RL7_HUMAN 1 1361.8345 1.19 113903 9023 3 1361.836333 454.9521 60S ribosomal protein L7 OS=Homo sapiens OX=9606 GN=RPL7 PE=1 SV=1 8.5 1933.7 - 1.31E+06 - - - 1.3812 - 1.895 0.311 - 184.9 1 2 1 0.0019 12 0 0 0 4.04E+07 3.41E+07 - - - 3.7786 0.9995 221125_WJC_METTL3_EV_vs_WT_F08.09024.09024.3 9.44E-05 14/48 K.DRPVSQPSLVGSK.E "sp|Q9H4A3|WNK1_HUMAN,tr|F5GWT4|F5GWT4_HUMAN,tr|F6UYG0|F6UYG0_HUMAN" 3 1368.7361 2.97 113904 9024 3 1368.739729 457.2527 Serine\threonine-protein kinase WNK1 OS=Homo sapiens OX=9606 GN=WNK1 PE=1 SV=2 8.75 1933.8 - 892184 - - - 2.6309 - 2.331 0.355 - 340.1 1 2 0 0.0036 13 0 0 0 2.98E+07 1.00E+07 - - - 4.7915 0.9997 221125_WJC_METTL3_EV_vs_WT_F08.09025.09025.3 0.0183 14/48 K.DR[166.11]PVSQPSLVGSK[136.11].E "sp|Q9H4A3|WNK1_HUMAN,tr|F5GWT4|F5GWT4_HUMAN,tr|F6UYG0|F6UYG0_HUMAN" 3 1386.7586 2.62 113905 9025 3 1386.760727 463.2601 Serine\threonine-protein kinase WNK1 OS=Homo sapiens OX=9606 GN=WNK1 PE=1 SV=2 8.75 1933.9 - 635841 - - - 1.5352 - 2.265 0.343 - 341.3 1 2 0 0.0021 13 0 0 0 2.63E+07 1.00E+07 - - - 4.5802 1 221125_WJC_METTL3_EV_vs_WT_F08.09033.09033.3 1.16E-07 16/40 M.GHQQLYWSHPR.K "sp|P62273|RS29_HUMAN,tr|A0A2R8Y851|A0A2R8Y851_HUMAN" 2 1407.6796 1.03 113911 9033 3 1407.682257 470.2338 40S ribosomal protein S29 OS=Homo sapiens OX=9606 GN=RPS29 PE=1 SV=2 8.76 1934.9 - 1.32E+06 - - - 1.8761 - 2.88 0.48 - 528.2 1 2 0 0.0026 11 0 0 0 8.45E+09 8.24E+09 - - - 6.8958 0.9997 221125_WJC_METTL3_EV_vs_WT_F08.09034.09034.3 0.00317 16/52 K.K[136.11]EPAASAAAFPSQR[166.11].T sp|Q9Y2X9|ZN281_HUMAN 1 1447.7538 1.65 113912 9034 3 1447.75863 483.5919 Zinc finger protein 281 OS=Homo sapiens OX=9606 GN=ZNF281 PE=1 SV=1 8.75 1935 - 690668 - - - 3.3037 - 2.932 0.391 - 313.5 1 2 0 0.0048 14 0 0 0 1.71E+07 1.04E+07 - - - 5.7566 0.9802 221125_WJC_METTL3_EV_vs_WT_F08.09037.09037.3 0.0215 Aug-56 K.AVNEQGKEVTEFGNK.Y "sp|Q9H7Z7|PGES2_HUMAN,tr|A0A7I2V5T7|A0A7I2V5T7_HUMAN,tr|A6NHH0|A6NHH0_HUMAN,tr|X6RJ95|X6RJ95_HUMAN,tr|A0A7I2V5X6|A0A7I2V5X6_HUMAN" 5 1648.8057 0.67 113915 9037 3 1648.809965 550.6092 Prostaglandin E synthase 2 OS=Homo sapiens OX=9606 GN=PTGES2 PE=1 SV=1 4.79 1935.4 - 307379 - - - 2.6086 - 1.272 0.346 - 38.6 1 2 1 0.0043 15 0 0 0 5.24E+06 7.78E+06 - - - 3.0242 1 221125_WJC_METTL3_EV_vs_WT_F08.09038.09038.2 5.59E-11 14/28 R.AESC[160.03]GSGNSTGYQIR.L "sp|Q9H2U1|DHX36_HUMAN,tr|E7EWK3|E7EWK3_HUMAN" 2 1585.6791 1.15 113916 9038 2 1585.681364 793.8468 ATP-dependent DNA\RNA helicase DHX36 OS=Homo sapiens OX=9606 GN=DHX36 PE=1 SV=2 6.04 1935.5 - 191003 - - - 1.4379 - 3.327 0.653 - 831.7 1 2 0 0.0023 15 0 0 0 3.15E+07 2.74E+07 - - - 6.8187 1 221125_WJC_METTL3_EV_vs_WT_F08.09039.09039.2 4.95E-09 13/28 R.AESC[160.03]GSGNSTGYQIR[166.11].L "sp|Q9H2U1|DHX36_HUMAN,tr|E7EWK3|E7EWK3_HUMAN" 2 1595.6874 1.15 113917 9039 2 1595.687954 798.851 ATP-dependent DNA\RNA helicase DHX36 OS=Homo sapiens OX=9606 GN=DHX36 PE=1 SV=2 6.04 1935.6 - 178348 - - - 0.376 - 3.196 0.632 - 662.6 1 2 0 0.0006 15 0 0 0 3.15E+07 2.74E+07 - - - 6.5653 0.9998 221125_WJC_METTL3_EV_vs_WT_F08.09043.09043.2 0.000165 14/26 K.K[136.11]GPGEVAGTVTGQK[136.11].R "sp|Q86U44|MTA70_HUMAN,tr|F5H6D8|F5H6D8_HUMAN,tr|H0YFV6|H0YFV6_HUMAN,tr|B4DTN4|B4DTN4_HUMAN" 4 1343.738 0.001 113920 9043 2 1343.740607 672.8763 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 8.59 1936.1 - 383589 - - - 1.9557 - 3.225 0.497 - 460.5 1 2 0 0.0026 14 0 0 0 0.00E+00 7.95E+06 - - - 5.6494 0.9976 221125_WJC_METTL3_EV_vs_WT_F08.09045.09045.3 0.244 14/44 K.KKEVPAVPETLK.K sp|P18124|RL7_HUMAN 1 1337.7919 0.93 113921 9045 3 1337.793907 446.9379 60S ribosomal protein L7 OS=Homo sapiens OX=9606 GN=RPL7 PE=1 SV=1 8.5 1936.3 - 1.25E+06 - - - 1.5361 - 2.126 0.311 - 302.8 1 2 1 0.0021 12 0 0 0 2.79E+07 3.00E+07 - - - 4.0974 0.9999 221125_WJC_METTL3_EV_vs_WT_F08.09046.09046.2 5.29E-06 24-Oct R.SDSGGSSSEPFDR.H sp|P48634|PRC2A_HUMAN 1 1326.5324 1.11 113922 9046 2 1326.531435 664.2735 Protein PRRC2A OS=Homo sapiens OX=9606 GN=PRRC2A PE=1 SV=3 4.03 1936.4 - 342336 - - - -0.729 - 2.455 0.542 - 356.3 1 2 0 -0.001 13 0 0 0 7.87E+07 7.09E+07 - - - 5.349 1 221125_WJC_METTL3_EV_vs_WT_F08.09047.09047.3 6.44E-06 15/40 M.GHQQLYWSHPR[166.11].K "sp|P62273|RS29_HUMAN,tr|A0A2R8Y851|A0A2R8Y851_HUMAN" 2 1417.6879 1.03 113923 9047 3 1417.690812 473.5699 40S ribosomal protein S29 OS=Homo sapiens OX=9606 GN=RPS29 PE=1 SV=2 8.76 1936.5 - 7.12E+06 - - - 2.0639 - 2.463 0.56 - 418.2 1 2 0 0.0029 11 0 0 0 8.45E+09 8.23E+09 - - - 7.3433 0.9983 221125_WJC_METTL3_EV_vs_WT_F08.09048.09048.3 0.0107 Nov-48 K.EK[136.11]DIQEESTFSSR[166.11].K "sp|P42704|LPPRC_HUMAN,tr|A0A804HI14|A0A804HI14_HUMAN,tr|A0A804HL40|A0A804HL40_HUMAN,tr|A0A804HKJ0|A0A804HKJ0_HUMAN,tr|A0A804HKR3|A0A804HKR3_HUMAN,tr|A0A0C4DG06|A0A0C4DG06_HUMAN,tr|A0A804HIN4|A0A804HIN4_HUMAN,tr|A0A804HLG8|A0A804HLG8_HUMAN,tr|A0A804HIV5|A0A804HIV5_HUMAN,tr|A0A804HHY9|A0A804HHY9_HUMAN,tr|A0A804HJH8|A0A804HJH8_HUMAN,tr|B8ZZ38|B8ZZ38_HUMAN,tr|A0A804HI40|A0A804HI40_HUMAN,tr|A0A804HJZ1|A0A804HJZ1_HUMAN,tr|C9JCA9|C9JCA9_HUMAN,tr|A0A804HIQ7|A0A804HIQ7_HUMAN,tr|A0A804HK30|A0A804HK30_HUMAN,tr|A0A804HKI2|A0A804HKI2_HUMAN,tr|A0A804HIG4|A0A804HIG4_HUMAN,tr|A0A804HK02|A0A804HK02_HUMAN" 20 1572.7387 0.91 113924 9048 3 1572.740116 525.2535 "Leucine-rich PPR motif-containing protein, mitochondrial OS=Homo sapiens OX=9606 GN=LRPPRC PE=1 SV=3" 4.41 1936.5 - 2.27E+06 - - - 0.9315 - 2.058 0.326 - 129.8 1 2 1 0.0015 13 0 0 0 5.28E+07 5.80E+07 - - - 4.131 0.9959 221125_WJC_METTL3_EV_vs_WT_F08.09050.09050.3 6.02E-06 Nov-56 F.SQPPAPPHQNTFPPR.S sp|Q96I24|FUBP3_HUMAN 1 1669.8325 999 113926 9050 3 1669.835352 557.6181 Far upstream element-binding protein 3 OS=Homo sapiens OX=9606 GN=FUBP3 PE=1 SV=2 9.49 1936.8 - 315015 - - - 1.7151 - 2.762 0.503 - 118.5 1 1 0 0.0029 15 0 0 0 1.45E+07 0.00E+00 - - - 6.7982 0.9993 221125_WJC_METTL3_EV_vs_WT_F08.09054.09054.2 8.40E-09 Oct-34 R.QGPAETGGQGQPQGPGLR[166.11].T "sp|O43819|SCO2_HUMAN,tr|A0A1W2PQK0|A0A1W2PQK0_HUMAN" 2 1743.8528 1.25 113930 9054 2 1743.859314 872.9337 "Protein SCO2 homolog, mitochondrial OS=Homo sapiens OX=9606 GN=SCO2 PE=1 SV=3" 6 1937.3 - 169737 - - - 3.7474 - 2.2 0.626 - 191.6 1 2 0 0.0065 18 0 0 0 4.86E+07 3.89E+07 - - - 5.601 0.9998 221125_WJC_METTL3_EV_vs_WT_F08.09058.09058.3 1.40E-06 Dec-52 K.K[136.11]GPGEVAGTVTGQK[136.11].R "sp|Q86U44|MTA70_HUMAN,tr|F5H6D8|F5H6D8_HUMAN,tr|H0YFV6|H0YFV6_HUMAN,tr|B4DTN4|B4DTN4_HUMAN" 4 1343.738 0.18 113932 9058 3 1343.742836 448.9199 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 8.59 1937.8 - 1.24E+06 - - - 3.6145 - 2.855 0.464 - 266.1 1 2 0 0.0049 14 0 0 0 9.47E+06 5.36E+07 - - - 6.4997 0.9502 221125_WJC_METTL3_EV_vs_WT_F08.09061.09061.3 0.000301 Sep-56 Q.GGSHGLFGNSTAQSR[166.11].G "sp|Q9UPQ9|TNR6B_HUMAN,tr|H0Y720|H0Y720_HUMAN" 2 1484.6996 2.77 113935 9061 3 1484.703169 495.9071 Trinucleotide repeat-containing gene 6B protein OS=Homo sapiens OX=9606 GN=TNRC6B PE=1 SV=4 9.76 1938 - 619228 - - - 2.422 - 1.825 0.402 - 43.7 1 1 0 0.0036 15 0 0 0 6.27E+07 2.26E+07 - - - 4.5906 0.9999 221125_WJC_METTL3_EV_vs_WT_F08.09063.09063.2 1.79E-06 14/20 M.GHQQLYWSHPR.K "sp|P62273|RS29_HUMAN,tr|A0A2R8Y851|A0A2R8Y851_HUMAN" 2 1407.6796 1.07 113937 9063 2 1407.678416 704.8471 40S ribosomal protein S29 OS=Homo sapiens OX=9606 GN=RPS29 PE=1 SV=2 8.76 1938.3 - 393269 - - - -0.8525 - 2.664 0.423 - 855.2 1 2 0 -0.0012 11 0 0 0 3.29E+08 3.07E+08 - - - 4.8156 1 221125_WJC_METTL3_EV_vs_WT_F08.09064.09064.2 2.42E-10 14/20 M.GHQQLYWSHPR[166.11].K "sp|P62273|RS29_HUMAN,tr|A0A2R8Y851|A0A2R8Y851_HUMAN" 2 1417.6879 1.07 113938 9064 2 1417.692654 709.8512 40S ribosomal protein S29 OS=Homo sapiens OX=9606 GN=RPS29 PE=1 SV=2 8.76 1938.4 - 372032 - - - 3.3632 - 2.875 0.536 - 826.3 1 2 0 0.0048 11 0 0 0 3.21E+08 3.02E+08 - - - 5.8553 1 221125_WJC_METTL3_EV_vs_WT_F08.09065.09065.3 1.26E-10 17/68 R.QGPAETGGQGQPQGPGLR[166.11].T "sp|O43819|SCO2_HUMAN,tr|A0A1W2PQK0|A0A1W2PQK0_HUMAN" 2 1743.8528 1.43 113939 9065 3 1743.852205 582.2915 "Protein SCO2 homolog, mitochondrial OS=Homo sapiens OX=9606 GN=SCO2 PE=1 SV=3" 6 1938.6 - 367041 - - - -0.3292 - 3.228 0.501 - 205.2 1 2 0 -0.0006 18 0 0 0 5.21E+07 3.65E+07 - - - 7.0436 1 221125_WJC_METTL3_EV_vs_WT_F08.09066.09066.2 3.03E-11 15/34 R.QGPAETGGQGQPQGPGLR.T "sp|O43819|SCO2_HUMAN,tr|A0A1W2PQK0|A0A1W2PQK0_HUMAN" 2 1733.8445 1.25 113940 9066 2 1733.850483 867.9295 "Protein SCO2 homolog, mitochondrial OS=Homo sapiens OX=9606 GN=SCO2 PE=1 SV=3" 6 1938.7 - 331332 - - - 3.4455 - 2.826 0.718 - 461.3 1 2 0 0.006 18 0 0 0 4.86E+07 3.89E+07 - - - 6.8964 0.9996 221125_WJC_METTL3_EV_vs_WT_F08.09067.09067.2 3.56E-05 28-Aug K.VDNSSLTGESEPQTR[166.11].S "sp|P05023|AT1A1_HUMAN,sp|P13637|AT1A3_HUMAN,sp|P50993|AT1A2_HUMAN,sp|P20648|ATP4A_HUMAN,tr|A0A0A0MT26|A0A0A0MT26_HUMAN,tr|M0QXF2|M0QXF2_HUMAN,tr|A0A2R8YEY8|A0A2R8YEY8_HUMAN,tr|B1AKY9|B1AKY9_HUMAN,tr|M0R116|M0R116_HUMAN" 9 1628.7517 1.47 113941 9067 2 1628.755084 815.3831 Sodium\potassium-transporting ATPase subunit alpha-1 OS=Homo sapiens OX=9606 GN=ATP1A1 PE=1 SV=1 4.14 1938.8 - 183850 - - - 2.0605 - 1.72 0.531 - 182.9 1 2 0 0.0034 15 0 0 0 6.10E+06 4.15E+06 - - - 4.2952 1 221125_WJC_METTL3_EV_vs_WT_F08.09074.09074.3 6.98E-08 17/68 R.QGPAETGGQGQPQGPGLR.T "sp|O43819|SCO2_HUMAN,tr|A0A1W2PQK0|A0A1W2PQK0_HUMAN" 2 1733.8445 1.43 113946 9074 3 1733.844771 578.9554 "Protein SCO2 homolog, mitochondrial OS=Homo sapiens OX=9606 GN=SCO2 PE=1 SV=3" 6 1939.7 - 690522 - - - 0.1511 - 3.082 0.526 - 247.4 1 2 0 0.0003 18 0 0 0 5.21E+07 3.65E+07 - - - 7.2071 0.9998 221125_WJC_METTL3_EV_vs_WT_F08.09082.09082.2 0.000105 24-Oct K.SNESVDIQDQEEK.V sp|Q5UIP0|RIF1_HUMAN 1 1519.6638 1.07 113953 9082 2 1519.66112 760.8392 Telomere-associated protein RIF1 OS=Homo sapiens OX=9606 GN=RIF1 PE=1 SV=2 3.83 1940.7 - 275121 - - - -1.7708 - 2.223 0.506 - 334.6 1 2 0 -0.0027 13 0 0 0 5.89E+06 5.50E+06 - - - 4.8278 0.9997 221125_WJC_METTL3_EV_vs_WT_F08.09086.09086.2 4.70E-06 13/24 K.SNESVDIQDQEEK[136.11].V sp|Q5UIP0|RIF1_HUMAN 1 1527.678 1.07 113956 9086 2 1527.674213 764.8463 Telomere-associated protein RIF1 OS=Homo sapiens OX=9606 GN=RIF1 PE=1 SV=2 3.83 1941.1 - 317547 - - - -2.4861 - 2.739 0.545 - 609.5 1 2 0 -0.0038 13 0 0 0 5.89E+06 5.50E+06 - - - 5.6512 0.9996 221125_WJC_METTL3_EV_vs_WT_F08.09089.09089.3 0.167 Sep-32 K.R[166.11]IFQIHTSR[166.11].M sp|P62191|PRS4_HUMAN 1 1176.6631 0.26 113957 9089 3 1176.661831 393.2283 26S proteasome regulatory subunit 4 OS=Homo sapiens OX=9606 GN=PSMC1 PE=1 SV=1 12 1941.4 - 619193 - - - -1.0487 - 1.935 0.307 - 126.8 1 2 0 -0.0012 9 0 0 0 2.65E+06 1.04E+07 - - - 3.9518 0.9776 221125_WJC_METTL3_EV_vs_WT_F08.09093.09093.3 0.00741 Jul-40 K.DSIK[136.11]LDDDSER[166.11].K "sp|Q86VP6|CAND1_HUMAN,tr|F5H6I6|F5H6I6_HUMAN" 2 1309.6117 0.84 113961 9093 3 1309.605676 437.5445 Cullin-associated NEDD8-dissociated protein 1 OS=Homo sapiens OX=9606 GN=CAND1 PE=1 SV=2 4.04 1942 - 596036 - - - -4.5685 - 2.002 0.309 - 70.7 1 2 1 -0.006 11 0 0 0 1.80E+07 2.13E+07 - - - 3.9553 0.9669 221125_WJC_METTL3_EV_vs_WT_F08.09096.09096.2 0.000809 12-Aug Q.LYWSHPR[166.11].K "sp|P62273|RS29_HUMAN,tr|A0A2R8Y851|A0A2R8Y851_HUMAN" 2 967.4904 1.08 113962 9096 2 967.49119 484.7525 40S ribosomal protein S29 OS=Homo sapiens OX=9606 GN=RPS29 PE=1 SV=2 8.75 1942.4 - 3.77E+06 - - - 0.862 - 1.429 0.398 - 313.4 1 1 0 0.0008 7 0 0 0 2.00E+08 1.85E+08 - - - 3.1115 0.9309 221125_WJC_METTL3_EV_vs_WT_F08.09097.09097.2 0.000857 12-Jul Q.LYWSHPR.K "sp|P62273|RS29_HUMAN,tr|A0A2R8Y851|A0A2R8Y851_HUMAN" 2 957.4821 1.08 113963 9097 2 957.480044 479.7483 40S ribosomal protein S29 OS=Homo sapiens OX=9606 GN=RPS29 PE=1 SV=2 8.75 1942.4 - 3.11E+06 - - - -2.1327 - 1.438 0.378 - 249.4 1 1 0 -0.002 7 0 0 0 2.00E+08 1.85E+08 - - - 2.9833 0.9994 221125_WJC_METTL3_EV_vs_WT_F08.09098.09098.3 0.00524 14/52 R.SPESRPSVVYPSTK.F "sp|P42694|HELZ_HUMAN,tr|J3QS41|J3QS41_HUMAN" 2 1532.7835 3.43 113964 9098 3 1532.779923 511.9351 Probable helicase with zinc finger domain OS=Homo sapiens OX=9606 GN=HELZ PE=1 SV=2 8.31 1942.6 - 1.23E+06 - - - -2.3154 - 2.329 0.324 - 181.7 1 2 0 -0.0035 14 0 0 0 3.18E+07 9.27E+06 - - - 4.3981 1 221125_WJC_METTL3_EV_vs_WT_F08.09099.09099.3 1.64E-06 15/56 R.SIAHPEEISSNSQVR.S "sp|Q8IYH5|ZZZ3_HUMAN,tr|C9JUA4|C9JUA4_HUMAN" 2 1652.8118 1.48 113965 9099 3 1652.80823 551.9445 ZZ-type zinc finger-containing protein 3 OS=Homo sapiens OX=9606 GN=ZZZ3 PE=1 SV=1 5.38 1942.7 - 669409 - - - -2.1672 - 2.855 0.518 - 302.4 1 2 0 -0.0036 15 0 0 0 3.44E+07 2.32E+07 - - - 7.0516 1 221125_WJC_METTL3_EV_vs_WT_F08.09105.09105.3 2.55E-07 19/60 K.ATVAAFAASEGHSHPR[166.11].V "sp|O14910|LIN7A_HUMAN,sp|Q9NUP9|LIN7C_HUMAN,tr|H0YIA8|H0YIA8_HUMAN,tr|G3V1D4|G3V1D4_HUMAN,tr|H0YI92|H0YI92_HUMAN" 5 1617.7887 1.3 113969 9105 3 1617.786907 540.2702 Protein lin-7 homolog A OS=Homo sapiens OX=9606 GN=LIN7A PE=1 SV=2 6.96 1943.4 - 1.21E+06 - - - -1.1225 - 2.685 0.579 - 449.9 1 2 0 -0.0018 16 0 0 0 5.92E+07 4.55E+07 - - - 7.529 0.9999 221125_WJC_METTL3_EV_vs_WT_F08.09106.09106.2 6.80E-05 14/20 R.RSTSSFSC[160.03]LSR.H sp|P35908|K22E_HUMAN 1 1286.6037 999 113970 9106 2 1286.60212 644.3091 "Keratin, type II cytoskeletal 2 epidermal OS=Homo sapiens OX=9606 GN=KRT2 PE=1 SV=2" 10.35 1943.6 - 807327 - - - -1.2545 - 2.829 0.475 - 201.9 1 2 0 -0.0016 11 0 0 0 8.19E+07 0.00E+00 - - - 5.3621 0.9999 221125_WJC_METTL3_EV_vs_WT_F08.09112.09112.4 0.000566 21/90 K.ATVAAFAASEGHSHPR[166.11].V "sp|O14910|LIN7A_HUMAN,sp|Q9NUP9|LIN7C_HUMAN,tr|H0YIA8|H0YIA8_HUMAN,tr|G3V1D4|G3V1D4_HUMAN,tr|H0YI92|H0YI92_HUMAN" 5 1617.7887 2.32 113974 9112 4 1617.786669 405.4545 Protein lin-7 homolog A OS=Homo sapiens OX=9606 GN=LIN7A PE=1 SV=2 6.96 1944.4 - 1.49E+06 - - - -1.2696 - 3.525 0.435 - 384.5 1 2 0 -0.0021 16 0 0 0 9.20E+07 3.96E+07 - - - 3.4555 0.9999 221125_WJC_METTL3_EV_vs_WT_F08.09115.09115.3 4.02E-07 13/56 R.SIAHPEEISSNSQVR[166.11].S "sp|Q8IYH5|ZZZ3_HUMAN,tr|C9JUA4|C9JUA4_HUMAN" 2 1662.8201 1.97 113976 9115 3 1662.815756 555.2806 ZZ-type zinc finger-containing protein 3 OS=Homo sapiens OX=9606 GN=ZZZ3 PE=1 SV=1 5.38 1944.7 - 839056 - - - -2.6016 - 2.457 0.476 - 317.3 1 2 0 -0.0043 15 0 0 0 3.42E+07 1.74E+07 - - - 6.1914 0.9999 221125_WJC_METTL3_EV_vs_WT_F08.09116.09116.3 0.0117 13/48 K.TLEQHDNIVTHYK.N sp|O60763|USO1_HUMAN 1 1596.7896 1.11 113977 9116 3 1596.788215 533.2705 General vesicular transport factor p115 OS=Homo sapiens OX=9606 GN=USO1 PE=1 SV=2 5.92 1944.8 - 1.17E+06 - - - -0.8799 - 2.248 0.397 - 157.6 1 2 0 -0.0014 13 0 0 0 1.89E+07 1.71E+07 - - - 5.162 0.9854 221125_WJC_METTL3_EV_vs_WT_F08.09117.09117.2 0.00254 16-Sep H.QQLYWSHPR[166.11].K "sp|P62273|RS29_HUMAN,tr|A0A2R8Y851|A0A2R8Y851_HUMAN" 2 1223.6075 1.16 113978 9117 2 1223.60679 612.811 40S ribosomal protein S29 OS=Homo sapiens OX=9606 GN=RPS29 PE=1 SV=2 8.75 1945 - 433685 - - - -0.5892 - 1.948 0.392 - 549.1 1 1 0 -0.0007 9 0 0 0 1.21E+07 1.04E+07 - - - 3.8652 0.9999 221125_WJC_METTL3_EV_vs_WT_F08.09131.09131.3 0.000228 Nov-40 R.RSTSSFSC[160.03]LSR.H sp|P35908|K22E_HUMAN 1 1286.6037 143.34 113988 9131 3 1286.601962 429.8752 "Keratin, type II cytoskeletal 2 epidermal OS=Homo sapiens OX=9606 GN=KRT2 PE=1 SV=2" 10.35 1946.6 - 1.05E+07 - - - -1.3773 - 2.204 0.425 - 139.5 1 2 0 -0.0018 11 0 0 0 2.64E+08 1.84E+06 - - - 5.5229 0.9693 221125_WJC_METTL3_EV_vs_WT_F08.09133.09133.2 0.00152 16-Oct H.QQLYWSHPR.K "sp|P62273|RS29_HUMAN,tr|A0A2R8Y851|A0A2R8Y851_HUMAN" 2 1213.5992 1.16 113990 9133 2 1213.596478 607.8069 40S ribosomal protein S29 OS=Homo sapiens OX=9606 GN=RPS29 PE=1 SV=2 8.75 1946.8 - 772549 - - - -2.2767 - 1.972 0.416 - 604.4 1 1 0 -0.0028 9 0 0 0 1.21E+07 1.04E+07 - - - 4.0772 1 221125_WJC_METTL3_EV_vs_WT_F08.09137.09137.3 1.28E-08 22/60 K.ATVAAFAASEGHSHPR.V "sp|O14910|LIN7A_HUMAN,sp|Q9NUP9|LIN7C_HUMAN,tr|H0YIA8|H0YIA8_HUMAN,tr|G3V1D4|G3V1D4_HUMAN,tr|H0YI92|H0YI92_HUMAN" 5 1607.7805 1.33 113992 9137 3 1607.776319 536.9341 Protein lin-7 homolog A OS=Homo sapiens OX=9606 GN=LIN7A PE=1 SV=2 6.96 1947.4 - 2.13E+06 - - - -2.5712 - 3.781 0.477 - 873.8 1 2 0 -0.0041 16 0 0 0 6.09E+07 4.58E+07 - - - 7.2695 0.9945 221125_WJC_METTL3_EV_vs_WT_F08.09138.09138.4 0.0091 18/78 K.VVDRDSEEAEIIRK.Y "sp|P09874|PARP1_HUMAN,tr|A0A7I2V3E1|A0A7I2V3E1_HUMAN" 2 1657.8635 0.98 113993 9138 4 1657.861917 415.4732 Poly [ADP-ribose] polymerase 1 OS=Homo sapiens OX=9606 GN=PARP1 PE=1 SV=4 4.51 1947.5 - 1.73E+06 - - - -0.9633 - 2.522 0.27 - 331.5 1 2 1 -0.0016 14 0 0 0 1.19E+08 1.22E+08 - - - 1.9123 0.9992 221125_WJC_METTL3_EV_vs_WT_F08.09141.09141.3 0.00156 15/36 K.NKYEDEINKR.T "sp|P48668|K2C6C_HUMAN,sp|P05787|K2C8_HUMAN,sp|P04264|K2C1_HUMAN,sp|P04259|K2C6B_HUMAN,sp|P13647|K2C5_HUMAN,sp|P02538|K2C6A_HUMAN,tr|F8VUG2|F8VUG2_HUMAN,tr|F8W0C6|F8W0C6_HUMAN,tr|F8VP67|F8VP67_HUMAN,tr|F8W1U3|F8W1U3_HUMAN" 10 1307.647 18.57 113996 9141 3 1307.643686 436.8896 "Keratin, type II cytoskeletal 6C OS=Homo sapiens OX=9606 GN=KRT6C PE=1 SV=3" 6.18 1947.9 - 572133 - - - -2.5183 - 2.415 0.407 - 320.1 1 2 1 -0.0033 10 0 0 0 1.58E+07 8.50E+05 - - - 5.6517 1 221125_WJC_METTL3_EV_vs_WT_F08.09143.09143.3 1.37E-06 20/68 R.EGATVYATGTHAQVEDGR[166.11].L "sp|P32322|P5CR1_HUMAN,tr|J3QKT4|J3QKT4_HUMAN,tr|J3QLK9|J3QLK9_HUMAN,tr|J3QL24|J3QL24_HUMAN,tr|E2QRB3|E2QRB3_HUMAN,tr|J3QL23|J3QL23_HUMAN,tr|J3QR88|J3QR88_HUMAN,tr|J3KQ22|J3KQ22_HUMAN,tr|J3QL32|J3QL32_HUMAN" 9 1870.8685 1.11 113998 9143 3 1870.869969 624.6301 "Pyrroline-5-carboxylate reductase 1, mitochondrial OS=Homo sapiens OX=9606 GN=PYCR1 PE=1 SV=2" 4.65 1948.1 - 341123 - - - 0.7911 - 3.23 0.561 - 450.1 1 2 0 0.0015 18 0 0 0 6.92E+07 6.24E+07 - - - 7.7138 0.9999 221125_WJC_METTL3_EV_vs_WT_F08.09147.09147.3 1.60E-06 14/44 K.ESESVDKVMDQK.E "sp|Q14103|HNRPD_HUMAN,tr|H0Y8G5|H0Y8G5_HUMAN,tr|D6RF44|D6RF44_HUMAN,tr|D6RBQ9|D6RBQ9_HUMAN,tr|D6RAF8|D6RAF8_HUMAN,tr|H0YA96|H0YA96_HUMAN" 6 1393.6395 0.07 114000 9147 3 1393.638179 465.5538 Heterogeneous nuclear ribonucleoprotein D0 OS=Homo sapiens OX=9606 GN=HNRNPD PE=1 SV=1 4.32 1948.7 - 4.11E+06 - - - -0.9551 - 2.705 0.537 - 296.3 1 2 1 -0.0013 12 0 0 0 1.45E+08 2.23E+09 - - - 7.2849 1 221125_WJC_METTL3_EV_vs_WT_F08.09148.09148.3 5.31E-06 24/52 K.VVDRDSEEAEIIRK.Y "sp|P09874|PARP1_HUMAN,tr|A0A7I2V3E1|A0A7I2V3E1_HUMAN" 2 1657.8635 1.01 114001 9148 3 1657.861486 553.6284 Poly [ADP-ribose] polymerase 1 OS=Homo sapiens OX=9606 GN=PARP1 PE=1 SV=4 4.51 1948.8 - 2.40E+06 - - - -1.2233 - 3.956 0.597 - 1314.7 1 2 1 -0.002 14 0 0 0 9.31E+07 9.25E+07 - - - 8.8501 1 221125_WJC_METTL3_EV_vs_WT_F08.09149.09149.2 9.96E-08 18/22 K.ESESVDKVMDQK.E "sp|Q14103|HNRPD_HUMAN,tr|H0Y8G5|H0Y8G5_HUMAN,tr|D6RF44|D6RF44_HUMAN,tr|D6RBQ9|D6RBQ9_HUMAN,tr|D6RAF8|D6RAF8_HUMAN,tr|H0YA96|H0YA96_HUMAN" 6 1393.6395 2.49 114002 9149 2 1393.63694 697.827 Heterogeneous nuclear ribonucleoprotein D0 OS=Homo sapiens OX=9606 GN=HNRNPD PE=1 SV=1 4.32 1948.9 - 755945 - - - -1.8441 - 2.994 0.612 - 915.4 1 2 1 -0.0026 12 0 0 0 2.12E+07 8.51E+06 - - - 6.4458 1 221125_WJC_METTL3_EV_vs_WT_F08.09155.09155.2 0.000454 15/34 R.GTSFDAAATSGGSASSEK.A "sp|P13804|ETFA_HUMAN,tr|H0YK49|H0YK49_HUMAN,tr|H0YL12|H0YL12_HUMAN,tr|H0YKF0|H0YKF0_HUMAN,tr|H0YLU7|H0YLU7_HUMAN,tr|H0YNX6|H0YNX6_HUMAN" 6 1629.7118 1.93 114004 9155 2 1629.709224 815.8632 "Electron transfer flavoprotein subunit alpha, mitochondrial OS=Homo sapiens OX=9606 GN=ETFA PE=1 SV=1" 4.37 1949.6 - 826493 - - - -1.5954 - 3.245 0.622 - 707.9 1 2 0 -0.0026 18 0 0 0 5.48E+07 2.84E+07 - - - 6.5283 0.9986 221125_WJC_METTL3_EV_vs_WT_F08.09156.09156.2 0.154 12-Jul R.FSGVPDR.F "sp|A0A075B6R9|KVD24_HUMAN,sp|A0A0C4DH68|KV224_HUMAN,sp|A2NJV5|KV229_HUMAN,sp|A0A075B6S2|KVD29_HUMAN,sp|A0A0A0MRZ7|KVD26_HUMAN" 5 776.3817 172.68 114005 9156 2 776.380702 389.1981 Probable non-functional immunoglobulin kappa variable 2D-24 OS=Homo sapiens OX=9606 GN=IGKV2D-24 PE=1 SV=1 5.84 1949.7 - 2.48E+06 - - - -1.2893 - 1.424 0.3 - 152.5 1 2 0 -0.001 7 0 0 0 3.07E+08 1.78E+06 - - - 2.3765 1 221125_WJC_METTL3_EV_vs_WT_F08.09161.09161.3 1.24E-08 24/68 R.EGATVYATGTHAQVEDGR.L "sp|P32322|P5CR1_HUMAN,tr|J3QKT4|J3QKT4_HUMAN,tr|J3QLK9|J3QLK9_HUMAN,tr|J3QL24|J3QL24_HUMAN,tr|E2QRB3|E2QRB3_HUMAN,tr|J3QL23|J3QL23_HUMAN,tr|J3QR88|J3QR88_HUMAN,tr|J3KQ22|J3KQ22_HUMAN,tr|J3QL32|J3QL32_HUMAN" 9 1860.8602 1.11 114008 9161 3 1860.857626 621.294 "Pyrroline-5-carboxylate reductase 1, mitochondrial OS=Homo sapiens OX=9606 GN=PYCR1 PE=1 SV=2" 4.65 1950.3 - 2.62E+06 - - - -1.3934 - 3.579 0.647 - 543.6 1 2 0 -0.0026 18 0 0 0 6.95E+07 6.24E+07 - - - 8.9278 1 221125_WJC_METTL3_EV_vs_WT_F08.09162.09162.3 0.000233 17/52 R.SSSLGSTPHEELER[166.11].L "sp|Q9NRA8|4ET_HUMAN,tr|B1AKL4|B1AKL4_HUMAN" 2 1537.7248 1.84 114009 9162 3 1537.722668 513.5822 Eukaryotic translation initiation factor 4E transporter OS=Homo sapiens OX=9606 GN=EIF4ENIF1 PE=1 SV=2 4.75 1950.4 - 1.78E+06 - - - -1.3767 - 2.848 0.498 - 514.9 1 2 0 -0.0021 14 0 0 0 3.41E+08 1.85E+08 - - - 6.873 0.9999 221125_WJC_METTL3_EV_vs_WT_F08.09163.09163.3 0.000617 15/52 R.SSSLGSTPHEELER.L "sp|Q9NRA8|4ET_HUMAN,tr|B1AKL4|B1AKL4_HUMAN" 2 1527.7165 1.44 114010 9163 3 1527.713881 510.2461 Eukaryotic translation initiation factor 4E transporter OS=Homo sapiens OX=9606 GN=EIF4ENIF1 PE=1 SV=2 4.75 1950.5 - 1.81E+06 - - - -1.7241 - 2.839 0.434 - 378.2 1 2 0 -0.0026 14 0 0 0 2.66E+08 1.85E+08 - - - 6.1509 0.9997 221125_WJC_METTL3_EV_vs_WT_F08.09166.09166.2 1.48E-06 14/28 K.GSC[160.03]GIGGGIGGGSSR.L "sp|P02533|K1C14_HUMAN,sp|P08779|K1C16_HUMAN,tr|K7ENV3|K7ENV3_HUMAN" 3 1277.5782 278.37 114013 9166 2 1277.575252 639.7964 "Keratin, type I cytoskeletal 14 OS=Homo sapiens OX=9606 GN=KRT14 PE=1 SV=4" 8.25 1950.9 - 492833 - - - -2.3443 - 2.423 0.565 - 406.9 1 2 0 -0.003 15 0 0 0 6.23E+07 2.24E+05 - - - 5.389 1 221125_WJC_METTL3_EV_vs_WT_F08.09170.09170.3 4.35E-06 16/52 K.VVDR[166.11]DSEEAEIIR[166.11]K[136.11].Y "sp|P09874|PARP1_HUMAN,tr|A0A7I2V3E1|A0A7I2V3E1_HUMAN" 2 1685.8943 1.01 114015 9170 3 1685.89274 562.972 Poly [ADP-ribose] polymerase 1 OS=Homo sapiens OX=9606 GN=PARP1 PE=1 SV=4 4.51 1951.4 - 7.22E+06 - - - -0.898 - 3.34 0.609 - 434.7 1 2 1 -0.0015 14 0 0 0 9.30E+07 9.25E+07 - - - 8.5342 0.8777 221125_WJC_METTL3_EV_vs_WT_F08.09171.09171.4 0.366 Dec-96 K.SIGTANRPMGAGEALRR.V "sp|Q12906|ILF3_HUMAN,tr|K7EQR9|K7EQR9_HUMAN" 2 1755.9162 1.05 114016 9171 4 1755.91652 439.9863 Interleukin enhancer-binding factor 3 OS=Homo sapiens OX=9606 GN=ILF3 PE=1 SV=3 11.7 1951.5 - 876842 - - - 0.1623 - 1.546 0.108 - 58.5 1 2 0 0.0003 17 0 0 0 2.28E+07 2.16E+07 - - - 0.3172 0.9999 221125_WJC_METTL3_EV_vs_WT_F08.09173.09173.4 9.31E-07 21/78 K.R[166.11]PAEDMEEEQAFK[136.11]R[166.11].S "sp|P61978|HNRPK_HUMAN,tr|S4R457|S4R457_HUMAN,tr|Q5T6W2|Q5T6W2_HUMAN" 3 1762.8303 1.79 114018 9173 4 1762.825821 441.7148 Heterogeneous nuclear ribonucleoprotein K OS=Homo sapiens OX=9606 GN=HNRNPK PE=1 SV=1 4.59 1951.8 - 924940 - - - -2.5255 - 3.749 0.493 - 598.2 1 2 0 -0.0045 14 0 0 0 7.30E+07 4.07E+07 - - - 3.9968 1 221125_WJC_METTL3_EV_vs_WT_F08.09179.09179.3 6.25E-11 18/44 K.C[160.03]NTDDTIGDLKK.L sp|Q9BZL1|UBL5_HUMAN 1 1378.6398 2.02 114022 9179 3 1378.638469 460.5539 Ubiquitin-like protein 5 OS=Homo sapiens OX=9606 GN=UBL5 PE=1 SV=1 4.43 1952.6 - 5.47E+06 - - - -0.9981 - 2.83 0.645 - 422.6 1 2 0 -0.0014 12 0 0 0 9.53E+08 4.72E+08 - - - 8.6142 1 221125_WJC_METTL3_EV_vs_WT_F08.09180.09180.3 3.46E-09 24/52 K.R[166.11]PAEDMEEEQAFK[136.11]R[166.11].S "sp|P61978|HNRPK_HUMAN,tr|S4R457|S4R457_HUMAN,tr|Q5T6W2|Q5T6W2_HUMAN" 3 1762.8303 1.29 114023 9180 3 1762.829613 588.6174 Heterogeneous nuclear ribonucleoprotein K OS=Homo sapiens OX=9606 GN=HNRNPK PE=1 SV=1 4.59 1952.6 - 2.65E+06 - - - -0.3744 - 4.112 0.664 - 1154 1 2 0 -0.0007 14 0 0 0 1.01E+08 7.82E+07 - - - 9.7003 1 221125_WJC_METTL3_EV_vs_WT_F08.09182.09182.3 7.42E-09 19/52 K.RPAEDMEEEQAFKR.S "sp|P61978|HNRPK_HUMAN,tr|S4R457|S4R457_HUMAN,tr|Q5T6W2|Q5T6W2_HUMAN" 3 1734.7995 1.3 114025 9182 3 1734.793995 579.2738 Heterogeneous nuclear ribonucleoprotein K OS=Homo sapiens OX=9606 GN=HNRNPK PE=1 SV=1 4.59 1952.8 - 2.84E+06 - - - -3.1923 - 3.784 0.666 - 639.4 1 2 0 -0.0055 14 0 0 0 1.01E+08 7.82E+07 - - - 9.5003 1 221125_WJC_METTL3_EV_vs_WT_F08.09185.09185.2 2.65E-10 17/34 R.GTSFDAAATSGGSASSEK[136.11].A "sp|P13804|ETFA_HUMAN,tr|H0YK49|H0YK49_HUMAN,tr|H0YL12|H0YL12_HUMAN,tr|H0YKF0|H0YKF0_HUMAN,tr|H0YLU7|H0YLU7_HUMAN,tr|H0YNX6|H0YNX6_HUMAN" 6 1637.726 1.9 114028 9185 2 1637.72292 819.8703 "Electron transfer flavoprotein subunit alpha, mitochondrial OS=Homo sapiens OX=9606 GN=ETFA PE=1 SV=1" 4.37 1953 - 1.50E+06 - - - -1.8953 - 3.283 0.733 - 805.6 1 2 0 -0.0031 18 0 0 0 5.34E+07 2.81E+07 - - - 7.3766 0.9745 221125_WJC_METTL3_EV_vs_WT_F08.09187.09187.3 0.00057 Oct-56 K.LSDNPAWEGDK[136.11]GNTK[136.11].G "sp|Q9BY42|RTF2_HUMAN,tr|A0A0A0MQR2|A0A0A0MQR2_HUMAN,tr|A2A2L6|A2A2L6_HUMAN,tr|A2A2L5|A2A2L5_HUMAN" 4 1646.7871 0.31 114030 9187 3 1646.779147 549.9363 Replication termination factor 2 OS=Homo sapiens OX=9606 GN=RTF2 PE=1 SV=3 4.56 1953.3 - 601696 - - - -4.8379 - 1.774 0.356 - 78 1 2 1 -0.008 15 0 0 0 1.70E+06 5.55E+06 - - - 4.0026 0.9999 221125_WJC_METTL3_EV_vs_WT_F08.09188.09188.2 5.93E-06 15/26 R.SSSLGSTPHEELER.L "sp|Q9NRA8|4ET_HUMAN,tr|B1AKL4|B1AKL4_HUMAN" 2 1527.7165 2.67 114031 9188 2 1527.715496 764.8655 Eukaryotic translation initiation factor 4E transporter OS=Homo sapiens OX=9606 GN=EIF4ENIF1 PE=1 SV=2 4.75 1953.4 - 531747 - - - -0.667 - 2.663 0.511 - 593.7 1 2 0 -0.001 14 0 0 0 3.28E+07 1.23E+07 - - - 5.2728 1 221125_WJC_METTL3_EV_vs_WT_F08.09193.09193.4 6.44E-06 16/78 K.RPAEDMEEEQAFKR.S "sp|P61978|HNRPK_HUMAN,tr|S4R457|S4R457_HUMAN,tr|Q5T6W2|Q5T6W2_HUMAN" 3 1734.7995 1.79 114034 9193 4 1734.795782 434.7072 Heterogeneous nuclear ribonucleoprotein K OS=Homo sapiens OX=9606 GN=HNRNPK PE=1 SV=1 4.59 1954.1 - 3.40E+06 - - - -2.1622 - 2.463 0.52 - 243.3 1 2 0 -0.0038 14 0 0 0 7.40E+07 4.14E+07 - - - 4.0791 0.8661 221125_WJC_METTL3_EV_vs_WT_F08.09194.09194.4 1.49 Oct-96 K.SIGTANR[166.11]PMGAGEALR[166.11]R[166.11].V "sp|Q12906|ILF3_HUMAN,tr|K7EQR9|K7EQR9_HUMAN" 2 1785.941 1.05 114035 9194 4 1785.939904 447.4925 Interleukin enhancer-binding factor 3 OS=Homo sapiens OX=9606 GN=ILF3 PE=1 SV=3 11.7 1954.1 - 2.52E+06 - - - -0.6389 - 1.185 0.115 - 45.3 1 2 0 -0.0011 17 0 0 0 2.28E+07 2.17E+07 - - - 0.2856 0.9981 221125_WJC_METTL3_EV_vs_WT_F08.09195.09195.3 0.0645 May-60 K.ELNNTC[160.03]EPVVTQPK[136.11]PK[136.11].L "sp|Q92598|HS105_HUMAN,tr|Q5TBM3|Q5TBM3_HUMAN,tr|A0A0A0MSM0|A0A0A0MSM0_HUMAN" 3 1868.9637 0.12 114036 9195 3 1868.961843 623.9952 Heat shock protein 105 kDa OS=Homo sapiens OX=9606 GN=HSPH1 PE=1 SV=1 6.23 1954.2 - 4.52E+06 - - - -0.9931 - 1.365 0.317 - 32.1 1 2 0 -0.0019 16 0 0 0 1.35E+07 1.17E+08 - - - 2.8721 0.9969 221125_WJC_METTL3_EV_vs_WT_F08.09198.09198.4 0.0144 Nov-84 R.FRPAGAAPRPPPKPM.- "sp|Q5JNZ5|RS26L_HUMAN,sp|P62854|RS26_HUMAN" 2 1588.866 1.01 114039 9198 4 1588.865906 398.2238 Putative 40S ribosomal protein S26-like 1 OS=Homo sapiens OX=9606 GN=RPS26P11 PE=5 SV=1 12.01 1954.4 - 880476 - - - -0.0824 - 1.814 0.248 - 57.2 1 2 0 -0.0001 15 0 0 0 2.35E+07 2.33E+07 - - - 1.5976 1 221125_WJC_METTL3_EV_vs_WT_F08.09202.09202.2 2.03E-09 15/22 K.C[160.03]NTDDTIGDLKK.L sp|Q9BZL1|UBL5_HUMAN 1 1378.6398 2.28 114041 9202 2 1378.638144 690.3272 Ubiquitin-like protein 5 OS=Homo sapiens OX=9606 GN=UBL5 PE=1 SV=1 4.43 1955 - 1.59E+06 - - - -1.2338 - 2.783 0.654 - 869 1 2 0 -0.0017 12 0 0 0 7.69E+07 3.37E+07 - - - 6.564 0.9999 221125_WJC_METTL3_EV_vs_WT_F08.09203.09203.4 6.65E-05 18/90 K.ATVAAFAASEGHSHPR.V "sp|O14910|LIN7A_HUMAN,sp|Q9NUP9|LIN7C_HUMAN,tr|H0YIA8|H0YIA8_HUMAN,tr|G3V1D4|G3V1D4_HUMAN,tr|H0YI92|H0YI92_HUMAN" 5 1607.7805 2.36 114042 9203 4 1607.778754 402.9524 Protein lin-7 homolog A OS=Homo sapiens OX=9606 GN=LIN7A PE=1 SV=2 6.96 1955 - 1.50E+06 - - - -1.0567 - 2.746 0.425 - 218 1 2 0 -0.0017 16 0 0 0 9.52E+07 4.04E+07 - - - 3.2806 1 221125_WJC_METTL3_EV_vs_WT_F08.09206.09206.2 1.94E-06 15/26 R.SSSLGSTPHEELER[166.11].L "sp|Q9NRA8|4ET_HUMAN,tr|B1AKL4|B1AKL4_HUMAN" 2 1537.7248 2.4 114045 9206 2 1537.722891 769.8697 Eukaryotic translation initiation factor 4E transporter OS=Homo sapiens OX=9606 GN=EIF4ENIF1 PE=1 SV=2 4.75 1955.3 - 1.01E+06 - - - -1.2317 - 2.595 0.591 - 675.2 1 2 0 -0.0019 14 0 0 0 2.95E+07 1.23E+07 - - - 5.7985 0.9948 221125_WJC_METTL3_EV_vs_WT_F08.09213.09213.2 1.39E-06 13/22 S.SLGSTPHEELER.L "sp|Q9NRA8|4ET_HUMAN,tr|B1AKL4|B1AKL4_HUMAN" 2 1353.6525 0.49 114052 9213 2 1353.651888 677.8335 Eukaryotic translation initiation factor 4E transporter OS=Homo sapiens OX=9606 GN=EIF4ENIF1 PE=1 SV=2 4.75 1956.2 - 202196 - - - -0.4211 - 2.298 0.588 - 575 1 1 0 -0.0006 12 0 0 0 2.57E+06 5.28E+06 - - - 5.573 1 221125_WJC_METTL3_EV_vs_WT_F08.09216.09216.3 3.86E-09 17/56 R.APQEFMTSHSEAGSR[166.11].L sp|Q9BRR6|ADPGK_HUMAN 1 1643.7237 1.28 114053 9216 3 1643.72363 548.9152 ADP-dependent glucokinase OS=Homo sapiens OX=9606 GN=ADPGK PE=1 SV=1 5.4 1956.6 - 1.01E+06 - - - -0.0663 - 3.16 0.575 - 488.2 1 2 0 -0.0001 15 0 0 0 2.82E+07 2.21E+07 - - - 7.9529 1 221125_WJC_METTL3_EV_vs_WT_F08.09221.09221.3 0.000436 19/56 R.APQEFMTSHSEAGSR.L sp|Q9BRR6|ADPGK_HUMAN 1 1633.7155 1.1 114058 9221 3 1633.717795 545.5791 ADP-dependent glucokinase OS=Homo sapiens OX=9606 GN=ADPGK PE=1 SV=1 5.4 1956.9 - 1.08E+06 - - - 1.4237 - 3.349 0.522 - 556 1 2 0 0.0023 15 0 0 0 2.94E+07 2.69E+07 - - - 7.513 1 221125_WJC_METTL3_EV_vs_WT_F08.09223.09223.3 3.87E-07 14/60 K.ELNNTC[160.03]EPVVTQPKPK.L "sp|Q92598|HS105_HUMAN,tr|Q5TBM3|Q5TBM3_HUMAN,tr|A0A0A0MSM0|A0A0A0MSM0_HUMAN" 3 1852.9353 0.12 114060 9223 3 1852.935851 618.6524 Heat shock protein 105 kDa OS=Homo sapiens OX=9606 GN=HSPH1 PE=1 SV=1 6.23 1957.1 - 897555 - - - 0.2979 - 2.425 0.564 - 282.3 1 2 0 0.0006 16 0 0 0 1.35E+07 1.17E+08 - - - 7.1008 1 221125_WJC_METTL3_EV_vs_WT_F08.09224.09224.2 2.13E-09 14/30 K.GPSYGEDVSNTTTAQK.R "sp|P29590|PML_HUMAN,tr|H3BVD2|H3BVD2_HUMAN" 2 1653.7482 1.76 114061 9224 2 1653.745847 827.8814 Protein PML OS=Homo sapiens OX=9606 GN=PML PE=1 SV=3 4.37 1957.3 - 605441 - - - -1.4283 - 2.861 0.648 - 482.9 1 2 0 -0.0024 16 0 0 0 2.84E+07 1.62E+07 - - - 6.4107 1 221125_WJC_METTL3_EV_vs_WT_F08.09225.09225.2 6.27E-09 28-Dec R.GSFSSTAAQDAQGQR.L sp|Q86V85|GP180_HUMAN 1 1509.6808 1.56 114062 9225 2 1509.682991 755.8477 Integral membrane protein GPR180 OS=Homo sapiens OX=9606 GN=GPR180 PE=2 SV=1 5.84 1957.4 - 586503 - - - 1.4526 - 2.818 0.662 - 387 1 2 0 0.0022 15 0 0 0 9.96E+06 6.37E+06 - - - 6.477 1 221125_WJC_METTL3_EV_vs_WT_F08.09226.09226.2 0.000305 15/30 K.GPSYGEDVSNTTTAQK[136.11].R "sp|P29590|PML_HUMAN,tr|H3BVD2|H3BVD2_HUMAN" 2 1661.7624 1.76 114063 9226 2 1661.759076 831.8885 Protein PML OS=Homo sapiens OX=9606 GN=PML PE=1 SV=3 4.37 1957.5 - 448000 - - - -2.0057 - 3.389 0.643 - 817.1 1 2 0 -0.0033 16 0 0 0 2.84E+07 1.62E+07 - - - 6.7899 0.9999 221125_WJC_METTL3_EV_vs_WT_F08.09229.09229.3 0.000371 17/52 K.QGIETPEDQNDLRK.M "sp|Q15637|SF01_HUMAN,tr|A0A7P0T9U7|A0A7P0T9U7_HUMAN" 2 1641.7958 1.21 114064 9229 3 1641.7925 548.2726 Splicing factor 1 OS=Homo sapiens OX=9606 GN=SF1 PE=1 SV=4 4.32 1958 - 1.81E+06 - - - -2.027 - 2.865 0.395 - 502.3 1 2 0 -0.0033 14 0 0 0 3.63E+08 2.99E+08 - - - 5.7402 0.9999 221125_WJC_METTL3_EV_vs_WT_F08.09230.09230.3 0.000341 19/52 K.QGIETPEDQNDLR[166.11]K[136.11].M "sp|Q15637|SF01_HUMAN,tr|A0A7P0T9U7|A0A7P0T9U7_HUMAN" 2 1659.8183 1.22 114065 9230 3 1659.814555 554.28 Splicing factor 1 OS=Homo sapiens OX=9606 GN=SF1 PE=1 SV=4 4.32 1958.1 - 1.37E+06 - - - -2.2551 - 2.935 0.397 - 520.5 1 2 0 -0.0037 14 0 0 0 3.63E+08 2.97E+08 - - - 5.8265 1 221125_WJC_METTL3_EV_vs_WT_F08.09233.09233.3 4.93E-09 15/52 R.ASLQETHFDSTQTK[136.11].Q "sp|O94888|UBXN7_HUMAN,tr|C9JAT7|C9JAT7_HUMAN" 2 1599.762 0.96 114068 9233 3 1599.762625 534.2613 UBX domain-containing protein 7 OS=Homo sapiens OX=9606 GN=UBXN7 PE=1 SV=2 5.32 1958.3 - 958387 - - - 0.3813 - 2.981 0.517 - 385.9 1 2 0 0.0006 14 0 0 0 1.89E+07 1.98E+07 - - - 7.2066 1 221125_WJC_METTL3_EV_vs_WT_F08.09234.09234.2 1.81E-07 16/26 K.EK[136.11]GSFSDTGLGDGK[136.11].M "sp|Q9Y2W1|TR150_HUMAN,tr|A0A3B3ITZ9|A0A3B3ITZ9_HUMAN" 2 1412.6754 2.15 114069 9234 2 1412.674334 707.345 Thyroid hormone receptor-associated protein 3 OS=Homo sapiens OX=9606 GN=THRAP3 PE=1 SV=2 4.56 1958.5 - 581618 - - - -0.7815 - 2.543 0.617 - 602.5 1 2 1 -0.0011 14 0 0 0 1.80E+08 8.34E+07 - - - 5.94 0.9986 221125_WJC_METTL3_EV_vs_WT_F08.09239.09239.2 9.05E-06 26-Dec K.EKGSFSDTGLGDGK.M "sp|Q9Y2W1|TR150_HUMAN,tr|A0A3B3ITZ9|A0A3B3ITZ9_HUMAN" 2 1396.647 2.16 114072 9239 2 1396.648287 699.3308 Thyroid hormone receptor-associated protein 3 OS=Homo sapiens OX=9606 GN=THRAP3 PE=1 SV=2 4.56 1959.1 - 3.19E+06 - - - 0.8943 - 2.138 0.585 - 320.5 1 2 1 0.0012 14 0 0 0 1.79E+08 8.28E+07 - - - 5.2683 1 221125_WJC_METTL3_EV_vs_WT_F08.09240.09240.3 0.00252 15/60 K.HTGPNSPDTANDGFVR[166.11].L "sp|P55795|HNRH2_HUMAN,sp|P31943|HNRH1_HUMAN,tr|E5RGH4|E5RGH4_HUMAN,tr|E7EQJ0|E7EQJ0_HUMAN,tr|D6RIH9|D6RIH9_HUMAN,tr|D6RJ04|D6RJ04_HUMAN,tr|E5RGV0|E5RGV0_HUMAN,tr|D6RFM3|D6RFM3_HUMAN,tr|E9PCY7|E9PCY7_HUMAN,tr|D6RIT2|D6RIT2_HUMAN,tr|D6R9T0|D6R9T0_HUMAN,tr|D6RIU0|D6RIU0_HUMAN,tr|H0YAQ2|H0YAQ2_HUMAN,tr|D6RAM1|D6RAM1_HUMAN,tr|D6RBM0|D6RBM0_HUMAN,tr|G8JLB6|G8JLB6_HUMAN,tr|D6RDU3|D6RDU3_HUMAN" 17 1693.7684 1.31 114073 9240 3 1693.768815 565.5967 Heterogeneous nuclear ribonucleoprotein H2 OS=Homo sapiens OX=9606 GN=HNRNPH2 PE=1 SV=1 5.21 1959.2 - 1.65E+06 - - - 0.2562 - 2.965 0.505 - 300.6 1 2 0 0.0004 16 0 0 0 3.37E+09 2.57E+09 - - - 6.9589 1 221125_WJC_METTL3_EV_vs_WT_F08.09241.09241.3 9.81E-07 15/60 K.HTGPNSPDTANDGFVR.L "sp|P55795|HNRH2_HUMAN,sp|P31943|HNRH1_HUMAN,tr|E5RGH4|E5RGH4_HUMAN,tr|E7EQJ0|E7EQJ0_HUMAN,tr|D6RIH9|D6RIH9_HUMAN,tr|D6RJ04|D6RJ04_HUMAN,tr|E5RGV0|E5RGV0_HUMAN,tr|D6RFM3|D6RFM3_HUMAN,tr|E9PCY7|E9PCY7_HUMAN,tr|D6RIT2|D6RIT2_HUMAN,tr|D6R9T0|D6R9T0_HUMAN,tr|D6RIU0|D6RIU0_HUMAN,tr|H0YAQ2|H0YAQ2_HUMAN,tr|D6RAM1|D6RAM1_HUMAN,tr|D6RBM0|D6RBM0_HUMAN,tr|G8JLB6|G8JLB6_HUMAN,tr|D6RDU3|D6RDU3_HUMAN" 17 1683.7601 1.31 114074 9241 3 1683.756647 562.2606 Heterogeneous nuclear ribonucleoprotein H2 OS=Homo sapiens OX=9606 GN=HNRNPH2 PE=1 SV=1 5.21 1959.2 - 1.73E+06 - - - -2.0573 - 3.023 0.478 - 357.6 1 2 0 -0.0035 16 0 0 0 3.37E+09 2.57E+09 - - - 6.7068 1 221125_WJC_METTL3_EV_vs_WT_F08.09243.09243.3 0.0001 14/52 R.ASLQETHFDSTQTK.Q "sp|O94888|UBXN7_HUMAN,tr|C9JAT7|C9JAT7_HUMAN" 2 1591.7478 0.86 114076 9243 3 1591.748285 531.5899 UBX domain-containing protein 7 OS=Homo sapiens OX=9606 GN=UBXN7 PE=1 SV=2 5.32 1959.4 - 1.47E+06 - - - 0.2953 - 2.76 0.462 - 304 1 2 0 0.0005 14 0 0 0 1.89E+07 2.21E+07 - - - 6.3887 0.9999 221125_WJC_METTL3_EV_vs_WT_F08.09244.09244.3 4.01E-06 Nov-44 K.C[160.03]NTDDTIGDLKK[136.11].L sp|Q9BZL1|UBL5_HUMAN 1 1386.654 - 114077 9244 3 1386.654567 463.2253 Ubiquitin-like protein 5 OS=Homo sapiens OX=9606 GN=UBL5 PE=1 SV=1 4.43 1959.5 - 1.40E+06 - - - 0.3764 - 2.255 0.423 - 169.2 1 2 0 0.0005 12 0 0 0 - - - - - 5.5098 0.9998 221125_WJC_METTL3_EV_vs_WT_F08.09252.09252.4 1.62E-06 17/78 R.MVNDAEK[136.11]FAEEDK[136.11]K[136.11].L "sp|P11021|BIP_HUMAN,tr|A0A7P0TB36|A0A7P0TB36_HUMAN,tr|A0A7P0TAI0|A0A7P0TAI0_HUMAN" 3 1676.8142 0.58 114083 9252 4 1676.811725 420.2108 Endoplasmic reticulum chaperone BiP OS=Homo sapiens OX=9606 GN=HSPA5 PE=1 SV=2 4.51 1960.4 - 665179 - - - -1.4683 - 2.498 0.491 - 196.3 1 2 1 -0.0025 14 0 0 0 9.54E+06 1.63E+07 - - - 3.8322 0.9996 221125_WJC_METTL3_EV_vs_WT_F08.09258.09258.3 0.00958 Nov-52 K.EK[136.11]GSFSDTGLGDGK[136.11].M "sp|Q9Y2W1|TR150_HUMAN,tr|A0A3B3ITZ9|A0A3B3ITZ9_HUMAN" 2 1412.6754 2.58 114087 9258 3 1412.674634 471.8991 Thyroid hormone receptor-associated protein 3 OS=Homo sapiens OX=9606 GN=THRAP3 PE=1 SV=2 4.56 1961.2 - 2.07E+07 - - - -0.5691 - 2.042 0.435 - 142.3 1 2 1 -0.0008 14 0 0 0 1.04E+09 4.03E+08 - - - 5.2869 0.9986 221125_WJC_METTL3_EV_vs_WT_F08.09259.09259.3 1.09E-06 Dec-48 K.GEFKDEEETVTTK.H sp|Q14677|EPN4_HUMAN 1 1511.6991 0.79 114088 9259 3 1511.691422 504.907 Clathrin interactor 1 OS=Homo sapiens OX=9606 GN=CLINT1 PE=1 SV=1 4.25 1961.2 - 5.29E+06 - - - -5.1015 - 2.225 0.583 - 168.8 1 2 1 -0.0077 13 0 0 0 2.44E+08 3.09E+08 - - - 7.2061 1 221125_WJC_METTL3_EV_vs_WT_F08.09260.09260.2 0.000264 18/38 K.AADPPAENSSAPEAEQGGAE.- "sp|P67809|YBOX1_HUMAN,tr|H0Y449|H0Y449_HUMAN" 2 1896.7973 - 114089 9260 2 1896.796962 949.4059 Y-box-binding protein 1 OS=Homo sapiens OX=9606 GN=YBX1 PE=1 SV=3 3.7 1961.3 - 977253 - - - -0.2014 - 3.334 0.642 - 893.6 1 2 0 -0.0004 20 0 0 0 - - - - - 6.7432 0.9999 221125_WJC_METTL3_EV_vs_WT_F08.09261.09261.2 0.000157 30-Oct K.HTGPNSPDTANDGFVR[166.11].L "sp|P55795|HNRH2_HUMAN,sp|P31943|HNRH1_HUMAN,tr|E5RGH4|E5RGH4_HUMAN,tr|E7EQJ0|E7EQJ0_HUMAN,tr|D6RIH9|D6RIH9_HUMAN,tr|D6RJ04|D6RJ04_HUMAN,tr|E5RGV0|E5RGV0_HUMAN,tr|D6RFM3|D6RFM3_HUMAN,tr|E9PCY7|E9PCY7_HUMAN,tr|D6RIT2|D6RIT2_HUMAN,tr|D6R9T0|D6R9T0_HUMAN,tr|D6RIU0|D6RIU0_HUMAN,tr|H0YAQ2|H0YAQ2_HUMAN,tr|D6RAM1|D6RAM1_HUMAN,tr|D6RBM0|D6RBM0_HUMAN,tr|G8JLB6|G8JLB6_HUMAN,tr|D6RDU3|D6RDU3_HUMAN" 17 1693.7684 1.28 114090 9261 2 1693.769614 847.8915 Heterogeneous nuclear ribonucleoprotein H2 OS=Homo sapiens OX=9606 GN=HNRNPH2 PE=1 SV=1 5.21 1961.5 - 499383 - - - 0.728 - 2.168 0.534 - 209.7 1 2 0 0.0012 16 0 0 0 1.90E+08 1.49E+08 - - - 4.8872 1 221125_WJC_METTL3_EV_vs_WT_F08.09262.09262.2 6.55E-05 14/30 K.HTGPNSPDTANDGFVR.L "sp|P55795|HNRH2_HUMAN,sp|P31943|HNRH1_HUMAN,tr|E5RGH4|E5RGH4_HUMAN,tr|E7EQJ0|E7EQJ0_HUMAN,tr|D6RIH9|D6RIH9_HUMAN,tr|D6RJ04|D6RJ04_HUMAN,tr|E5RGV0|E5RGV0_HUMAN,tr|D6RFM3|D6RFM3_HUMAN,tr|E9PCY7|E9PCY7_HUMAN,tr|D6RIT2|D6RIT2_HUMAN,tr|D6R9T0|D6R9T0_HUMAN,tr|D6RIU0|D6RIU0_HUMAN,tr|H0YAQ2|H0YAQ2_HUMAN,tr|D6RAM1|D6RAM1_HUMAN,tr|D6RBM0|D6RBM0_HUMAN,tr|G8JLB6|G8JLB6_HUMAN,tr|D6RDU3|D6RDU3_HUMAN" 17 1683.7601 1.28 114091 9262 2 1683.759578 842.8873 Heterogeneous nuclear ribonucleoprotein H2 OS=Homo sapiens OX=9606 GN=HNRNPH2 PE=1 SV=1 5.21 1961.6 - 423963 - - - -0.3166 - 2.577 0.638 - 458.3 1 2 0 -0.0005 16 0 0 0 1.90E+08 1.49E+08 - - - 6.0804 0.9994 221125_WJC_METTL3_EV_vs_WT_F08.09263.09263.2 4.81E-06 26-Sep R.QDSINAYNEPNSTK[136.11].F sp|O60264|SMCA5_HUMAN 1 1587.7256 0.92 114092 9263 2 1587.720249 794.8701 SWI\SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A member 5 OS=Homo sapiens OX=9606 GN=SMARCA5 PE=1 SV=1 4.37 1961.7 - 228864 - - - -3.3891 - 1.975 0.598 - 231.5 1 2 0 -0.0054 14 0 0 0 4.80E+06 5.21E+06 - - - 5.164 1 221125_WJC_METTL3_EV_vs_WT_F08.09270.09270.3 2.29E-08 15/56 R.THYSNIEANESEEVR.Q "sp|P04632|CPNS1_HUMAN,tr|A0A075B7C0|A0A075B7C0_HUMAN,tr|A0A0C4DGQ5|A0A0C4DGQ5_HUMAN,tr|K7ELJ7|K7ELJ7_HUMAN,tr|U3KQE2|U3KQE2_HUMAN,tr|K7EIV0|K7EIV0_HUMAN,tr|K7EM73|K7EM73_HUMAN" 7 1776.7915 1.27 114097 9270 3 1776.792295 593.2711 Calpain small subunit 1 OS=Homo sapiens OX=9606 GN=CAPNS1 PE=1 SV=1 4.48 1962.6 - 433933 - - - 0.4638 - 2.919 0.606 - 270.6 1 2 0 0.0008 15 0 0 0 1.07E+08 8.40E+07 - - - 8.0913 1 221125_WJC_METTL3_EV_vs_WT_F08.09271.09271.3 2.98E-09 15/56 R.THYSNIEANESEEVR[166.11].Q "sp|P04632|CPNS1_HUMAN,tr|A0A075B7C0|A0A075B7C0_HUMAN,tr|A0A0C4DGQ5|A0A0C4DGQ5_HUMAN,tr|K7ELJ7|K7ELJ7_HUMAN,tr|U3KQE2|U3KQE2_HUMAN,tr|K7EIV0|K7EIV0_HUMAN,tr|K7EM73|K7EM73_HUMAN" 7 1786.7997 1.27 114098 9271 3 1786.801117 596.6072 Calpain small subunit 1 OS=Homo sapiens OX=9606 GN=CAPNS1 PE=1 SV=1 4.48 1962.7 - 368625 - - - 0.7701 - 3.335 0.622 - 515 1 2 0 0.0014 15 0 0 0 1.06E+08 8.38E+07 - - - 8.6172 0.9946 221125_WJC_METTL3_EV_vs_WT_F08.09273.09273.2 2.45E-09 26-Dec R.HGSGSGQSSSYGPY.R "sp|Q86YZ3|HORN_HUMAN,sp|Q86YZ3|HORN_HUMAN" 2 1369.5535 - 114100 9273 2 1369.55371 685.784 Hornerin OS=Homo sapiens OX=9606 GN=HRNR PE=1 SV=2 6.74 1962.9 - 263096 - - - 0.1738 - 2.005 0.636 - 295.2 1 1 0 0.0002 14 0 0 0 - - - - - 5.4841 0.9812 221125_WJC_METTL3_EV_vs_WT_F08.09276.09276.3 0.000122 13/44 R.HYQHVLAVDPEK.A sp|Q06481|APLP2_HUMAN 1 1434.7256 3.86 114101 9276 3 1434.723858 479.2491 Amyloid beta precursor like protein 2 OS=Homo sapiens OX=9606 GN=APLP2 PE=1 SV=2 5.99 1963.4 - 2.30E+06 - - - -1.1884 - 2.287 0.058 - 295.1 1 2 0 -0.0017 12 0 0 0 5.18E+07 1.34E+07 - - - 1.4792 0.9999 221125_WJC_METTL3_EV_vs_WT_F08.09277.09277.2 4.25E-05 26-Aug R.QDSINAYNEPNSTK.F sp|O60264|SMCA5_HUMAN 1 1579.7114 0.92 114102 9277 2 1579.711812 790.863 SWI\SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A member 5 OS=Homo sapiens OX=9606 GN=SMARCA5 PE=1 SV=1 4.37 1963.5 - 210258 - - - 0.2418 - 1.629 0.605 - 155.2 1 2 0 0.0004 14 0 0 0 4.80E+06 5.21E+06 - - - 4.7339 1 221125_WJC_METTL3_EV_vs_WT_F08.09279.09279.2 3.80E-06 13/24 R.EVATNSELVQSGK.S "sp|Q04695|K1C17_HUMAN,sp|P02533|K1C14_HUMAN,tr|K7ESE1|K7ESE1_HUMAN,tr|F5GWP8|F5GWP8_HUMAN" 4 1360.6834 45.23 114104 9279 2 1360.684325 681.349 "Keratin, type I cytoskeletal 17 OS=Homo sapiens OX=9606 GN=KRT17 PE=1 SV=2" 4.53 1963.8 - 362417 - - - 0.6622 - 2.635 0.607 - 417.2 1 2 0 0.0009 13 0 0 0 2.15E+07 4.75E+05 - - - 6.0107 0.996 221125_WJC_METTL3_EV_vs_WT_F08.09286.09286.3 7.22E-05 Nov-64 R.YGDGGSTFQSTTGHC[160.03]VH.M "sp|P31943|HNRH1_HUMAN,tr|H0YBD7|H0YBD7_HUMAN,tr|H0YB39|H0YB39_HUMAN,tr|H0YBG7|H0YBG7_HUMAN,tr|E9PCY7|E9PCY7_HUMAN,tr|D6RIT2|D6RIT2_HUMAN,tr|G8JLB6|G8JLB6_HUMAN" 7 1809.7377 - 114109 9286 3 1809.735986 604.2532 Heterogeneous nuclear ribonucleoprotein H OS=Homo sapiens OX=9606 GN=HNRNPH1 PE=1 SV=4 5.97 1964.6 - 1.36E+06 - - - -0.9255 - 2.184 0.512 - 57.4 1 1 0 -0.0017 17 0 0 0 - - - - - 6.2213 0.9999 221125_WJC_METTL3_EV_vs_WT_F08.09289.09289.2 3.27E-07 24-Oct K.EHDPVGQMVNNPK[136.11].L sp|P55060|XPO2_HUMAN 1 1471.6969 1.06 114112 9289 2 1471.696083 736.8557 Exportin-2 OS=Homo sapiens OX=9606 GN=CSE1L PE=1 SV=3 5.32 1964.9 - 231208 - - - -0.5633 - 2.195 0.59 - 322.5 1 2 0 -0.0008 13 0 0 0 8.83E+06 8.35E+06 - - - 5.4162 1 221125_WJC_METTL3_EV_vs_WT_F08.09295.09295.3 9.58E-06 15/44 R.HYQHVLAVDPEK[136.11].A sp|Q06481|APLP2_HUMAN 1 1442.7398 4.66 114116 9295 3 1442.738133 481.9205 Amyloid beta precursor like protein 2 OS=Homo sapiens OX=9606 GN=APLP2 PE=1 SV=2 5.99 1965.7 - 704130 - - - -1.1298 - 2.805 0.455 - 307.6 1 2 0 -0.0016 12 0 0 0 6.46E+07 1.38E+07 - - - 6.4712 1 221125_WJC_METTL3_EV_vs_WT_F08.09302.09302.2 3.98E-07 18/24 R.K[136.11]QSTDEEVTSLAK[136.11].S "sp|P23193|TCEA1_HUMAN,tr|E5RJ93|E5RJ93_HUMAN,tr|A0A1W2PRL9|A0A1W2PRL9_HUMAN,tr|A0A1W2PPZ5|A0A1W2PPZ5_HUMAN,tr|E5RIS7|E5RIS7_HUMAN" 5 1450.7486 1.22 114121 9302 2 1450.747794 726.3816 Transcription elongation factor A protein 1 OS=Homo sapiens OX=9606 GN=TCEA1 PE=1 SV=2 4.68 1966.6 - 1.16E+06 - - - -0.5576 - 3.54 0.65 - 795.6 1 2 0 -0.0008 13 0 0 0 1.55E+07 1.27E+07 - - - 7.0861 1 221125_WJC_METTL3_EV_vs_WT_F08.09303.09303.2 4.15E-08 19/24 R.KQSTDEEVTSLAK.S "sp|P23193|TCEA1_HUMAN,tr|E5RJ93|E5RJ93_HUMAN,tr|A0A1W2PRL9|A0A1W2PRL9_HUMAN,tr|A0A1W2PPZ5|A0A1W2PPZ5_HUMAN,tr|E5RIS7|E5RIS7_HUMAN" 5 1434.7202 1.22 114122 9303 2 1434.718767 718.3674 Transcription elongation factor A protein 1 OS=Homo sapiens OX=9606 GN=TCEA1 PE=1 SV=2 4.68 1966.7 - 870166 - - - -1.0009 - 3.351 0.651 - 465.6 1 2 0 -0.0014 13 0 0 0 1.55E+07 1.27E+07 - - - 6.9524 0.9998 221125_WJC_METTL3_EV_vs_WT_F08.09304.09304.3 0.000902 Sep-48 K.EHDPVGQMVNNPK.L sp|P55060|XPO2_HUMAN 1 1463.6827 0.89 114123 9304 3 1463.68196 488.9015 Exportin-2 OS=Homo sapiens OX=9606 GN=CSE1L PE=1 SV=3 5.32 1966.8 - 2.72E+06 - - - -0.5138 - 1.656 0.423 - 60.4 1 2 0 -0.0008 13 0 0 0 6.59E+07 7.43E+07 - - - 4.6234 0.9999 221125_WJC_METTL3_EV_vs_WT_F08.09305.09305.3 4.50E-05 14/48 K.QQALTVSTDPEHR[166.11].F "sp|P35606|COPB2_HUMAN,tr|H0Y938|H0Y938_HUMAN,tr|A0A7I2V258|A0A7I2V258_HUMAN,tr|H0YAC7|H0YAC7_HUMAN" 4 1490.7353 0.73 114124 9305 3 1490.736833 497.919 Coatomer subunit beta' OS=Homo sapiens OX=9606 GN=COPB2 PE=1 SV=2 5.32 1966.9 - 805712 - - - 1.0351 - 2.481 0.44 - 280.9 1 2 0 0.0015 13 0 0 0 1.80E+07 2.45E+07 - - - 5.9088 1 221125_WJC_METTL3_EV_vs_WT_F08.09308.09308.2 5.16E-10 16/28 R.THYSNIEANESEEVR.Q "sp|P04632|CPNS1_HUMAN,tr|A0A075B7C0|A0A075B7C0_HUMAN,tr|A0A0C4DGQ5|A0A0C4DGQ5_HUMAN,tr|K7ELJ7|K7ELJ7_HUMAN,tr|U3KQE2|U3KQE2_HUMAN,tr|K7EIV0|K7EIV0_HUMAN,tr|K7EM73|K7EM73_HUMAN" 7 1776.7915 1.17 114127 9308 2 1776.791164 889.403 Calpain small subunit 1 OS=Homo sapiens OX=9606 GN=CAPNS1 PE=1 SV=1 4.48 1967.3 - 338750 - - - -0.1728 - 2.719 0.712 - 352.1 1 2 0 -0.0003 15 0 0 0 6.07E+06 5.20E+06 - - - 6.7589 1 221125_WJC_METTL3_EV_vs_WT_F08.09309.09309.2 8.93E-13 13/32 R.YGDGGSTFQSTTGHC[160.03]VH.M "sp|P31943|HNRH1_HUMAN,tr|H0YBD7|H0YBD7_HUMAN,tr|H0YB39|H0YB39_HUMAN,tr|H0YBG7|H0YBG7_HUMAN,tr|E9PCY7|E9PCY7_HUMAN,tr|D6RIT2|D6RIT2_HUMAN,tr|G8JLB6|G8JLB6_HUMAN" 7 1809.7377 - 114128 9309 2 1809.738459 905.8761 Heterogeneous nuclear ribonucleoprotein H OS=Homo sapiens OX=9606 GN=HNRNPH1 PE=1 SV=4 5.97 1967.4 - 248204 - - - 0.4409 - 2.867 0.727 - 471.7 1 1 0 0.0008 17 0 0 0 - - - - - 6.9999 1 221125_WJC_METTL3_EV_vs_WT_F08.09312.09312.3 0.000599 17/40 M.GHQQLYWSHPR.K "sp|P62273|RS29_HUMAN,tr|A0A2R8Y851|A0A2R8Y851_HUMAN" 2 1407.6796 1.03 114129 9312 3 1407.678335 470.2338 40S ribosomal protein S29 OS=Homo sapiens OX=9606 GN=RPS29 PE=1 SV=2 8.76 1967.8 - 1.33E+07 - - - -0.91 - 2.962 0.532 - 676.8 1 2 0 -0.0013 11 0 0 0 8.45E+09 8.24E+09 - - - 7.5557 1 221125_WJC_METTL3_EV_vs_WT_F08.09314.09314.3 1.07E-07 16/52 R.C[160.03]QLQQAAALNAQHK.Q sp|Q96DF8|ESS2_HUMAN 1 1579.7889 0.75 114131 9314 3 1579.788791 527.6036 Splicing factor ESS-2 homolog OS=Homo sapiens OX=9606 GN=ESS2 PE=1 SV=1 8.23 1968 - 2.76E+06 - - - -0.0747 - 3.352 0.523 - 445.8 1 2 0 -0.0001 14 0 0 0 4.02E+07 5.34E+07 - - - 7.5853 1 221125_WJC_METTL3_EV_vs_WT_F08.09316.09316.3 0.00023 24/52 R.C[160.03]QLQQAAALNAQHK[136.11].Q sp|Q96DF8|ESS2_HUMAN 1 1587.8031 0.71 114133 9316 3 1587.804287 530.275 Splicing factor ESS-2 homolog OS=Homo sapiens OX=9606 GN=ESS2 PE=1 SV=1 8.23 1968.1 - 1.71E+06 - - - 0.7419 - 4.123 0.547 - 1416.9 1 2 0 0.0012 14 0 0 0 4.02E+07 5.66E+07 - - - 8.4028 0.9997 221125_WJC_METTL3_EV_vs_WT_F08.09318.09318.2 0.242 26-Nov K.QGIETPEDQNDLRK.M "sp|Q15637|SF01_HUMAN,tr|A0A7P0T9U7|A0A7P0T9U7_HUMAN" 2 1641.7958 1.43 114135 9318 2 1641.792843 821.9052 Splicing factor 1 OS=Homo sapiens OX=9606 GN=SF1 PE=1 SV=4 4.32 1968.4 - 487004 - - - -1.8181 - 2.303 0.449 - 343.8 1 2 0 -0.003 14 0 0 0 1.12E+07 7.82E+06 - - - 4.4498 1 221125_WJC_METTL3_EV_vs_WT_F08.09320.09320.2 8.19E-09 16/28 R.THYSNIEANESEEVR[166.11].Q "sp|P04632|CPNS1_HUMAN,tr|A0A075B7C0|A0A075B7C0_HUMAN,tr|A0A0C4DGQ5|A0A0C4DGQ5_HUMAN,tr|K7ELJ7|K7ELJ7_HUMAN,tr|U3KQE2|U3KQE2_HUMAN,tr|K7EIV0|K7EIV0_HUMAN,tr|K7EM73|K7EM73_HUMAN" 7 1786.7997 1.17 114137 9320 2 1786.800438 894.4071 Calpain small subunit 1 OS=Homo sapiens OX=9606 GN=CAPNS1 PE=1 SV=1 4.48 1968.6 - 372032 - - - 0.3901 - 3.34 0.706 - 663.7 1 2 0 0.0007 15 0 0 0 6.07E+06 5.20E+06 - - - 7.2202 0.9982 221125_WJC_METTL3_EV_vs_WT_F08.09323.09323.3 1.46E-05 Oct-48 R.K[136.11]QSTDEEVTSLAK[136.11].S "sp|P23193|TCEA1_HUMAN,tr|E5RJ93|E5RJ93_HUMAN,tr|A0A1W2PRL9|A0A1W2PRL9_HUMAN,tr|A0A1W2PPZ5|A0A1W2PPZ5_HUMAN,tr|E5RIS7|E5RIS7_HUMAN" 5 1450.7486 1.01 114138 9323 3 1450.745855 484.5901 Transcription elongation factor A protein 1 OS=Homo sapiens OX=9606 GN=TCEA1 PE=1 SV=2 4.68 1969 - 3.13E+06 - - - -1.8942 - 1.97 0.259 - 143.9 1 2 0 -0.0027 13 0 0 0 5.50E+07 5.43E+07 - - - 3.2652 1 221125_WJC_METTL3_EV_vs_WT_F08.09325.09325.2 1.06E-10 16/34 R.LALSQNQQSSGAAGPTGK.N "sp|O95232|LC7L3_HUMAN,tr|J3KPP4|J3KPP4_HUMAN,tr|D6RDI2|D6RDI2_HUMAN" 3 1713.8646 1.21 114140 9325 2 1713.868136 857.9396 Luc7-like protein 3 OS=Homo sapiens OX=9606 GN=LUC7L3 PE=1 SV=2 8.75 1969.3 - 577346 - - - 2.0772 - 3.156 0.637 - 873.2 1 2 0 0.0036 18 0 0 0 1.94E+07 1.61E+07 - - - 6.5704 1 221125_WJC_METTL3_EV_vs_WT_F08.09326.09326.2 1.28E-11 17/34 R.LALSQNQQSSGAAGPTGK[136.11].N "sp|O95232|LC7L3_HUMAN,tr|J3KPP4|J3KPP4_HUMAN,tr|D6RDI2|D6RDI2_HUMAN" 3 1721.8788 1.21 114141 9326 2 1721.876082 861.9467 Luc7-like protein 3 OS=Homo sapiens OX=9606 GN=LUC7L3 PE=1 SV=2 8.75 1969.4 - 358556 - - - -1.5646 - 3.155 0.651 - 597.7 1 2 0 -0.0027 18 0 0 0 1.94E+07 1.61E+07 - - - 6.6733 0.9863 221125_WJC_METTL3_EV_vs_WT_F08.09330.09330.3 4.1 Dec-44 K.RDPHLAC[160.03]VAYER.G "sp|Q00610|CLH1_HUMAN,sp|P53675|CLH2_HUMAN,tr|A0A087WVQ6|A0A087WVQ6_HUMAN,tr|A0A087WX41|A0A087WX41_HUMAN" 4 1485.7147 1.27 114143 9330 3 1485.707732 496.2455 Clathrin heavy chain 1 OS=Homo sapiens OX=9606 GN=CLTC PE=1 SV=5 6.74 1969.9 - 1.03E+06 - - - -4.6772 - 2.169 0.23 - 164 1 2 0 -0.0069 12 0 0 0 2.84E+07 2.24E+07 - - - 3.2485 0.9999 221125_WJC_METTL3_EV_vs_WT_F08.09332.09332.3 1.57E-07 16/68 R.LALSQNQQSSGAAGPTGK[136.11].N "sp|O95232|LC7L3_HUMAN,tr|J3KPP4|J3KPP4_HUMAN,tr|D6RDI2|D6RDI2_HUMAN" 3 1721.8788 1.44 114145 9332 3 1721.874172 574.9669 Luc7-like protein 3 OS=Homo sapiens OX=9606 GN=LUC7L3 PE=1 SV=2 8.75 1970.1 - 478193 - - - -2.6738 - 3.003 0.529 - 301.6 1 2 0 -0.0046 18 0 0 0 1.47E+07 1.02E+07 - - - 7.1747 0.9997 221125_WJC_METTL3_EV_vs_WT_F08.09333.09333.2 0.143 26-Nov K.QGIETPEDQNDLR[166.11]K[136.11].M "sp|Q15637|SF01_HUMAN,tr|A0A7P0T9U7|A0A7P0T9U7_HUMAN" 2 1659.8183 1.43 114146 9333 2 1659.819695 830.9164 Splicing factor 1 OS=Homo sapiens OX=9606 GN=SF1 PE=1 SV=4 4.32 1970.2 - 416178 - - - 0.8417 - 2.329 0.34 - 354.7 1 2 0 0.0014 14 0 0 0 1.12E+07 7.82E+06 - - - 3.6734 0.9892 221125_WJC_METTL3_EV_vs_WT_F08.09344.09344.3 0.00358 Nov-60 K.ASLPTGEGSISHEEQK.S "sp|Q9BRQ6|MIC25_HUMAN,tr|J3QTB2|J3QTB2_HUMAN,tr|H0Y922|H0Y922_HUMAN,tr|J3QTA6|J3QTA6_HUMAN" 4 1668.7955 0.62 114153 9344 3 1668.801615 557.2724 MICOS complex subunit MIC25 OS=Homo sapiens OX=9606 GN=CHCHD6 PE=1 SV=1 4.75 1971.6 - 1.56E+06 - - - 3.6679 - 2.21 0.211 - 108 1 2 0 0.0061 16 0 0 0 2.53E+07 4.04E+07 - - - 2.9255 1 221125_WJC_METTL3_EV_vs_WT_F08.09350.09350.3 7.77E-09 15/68 R.LALSQNQQSSGAAGPTGK.N "sp|O95232|LC7L3_HUMAN,tr|J3KPP4|J3KPP4_HUMAN,tr|D6RDI2|D6RDI2_HUMAN" 3 1713.8646 1.4 114157 9350 3 1713.863639 572.2955 Luc7-like protein 3 OS=Homo sapiens OX=9606 GN=LUC7L3 PE=1 SV=2 8.75 1972.4 - 886264 - - - -0.5467 - 2.94 0.502 - 326.1 1 2 0 -0.0009 18 0 0 0 1.43E+07 1.02E+07 - - - 6.8219 1 221125_WJC_METTL3_EV_vs_WT_F08.09352.09352.3 5.45E-05 19/56 R.KLDYGQHVVAGTPGR.V "sp|P38919|IF4A3_HUMAN,tr|I3L3H2|I3L3H2_HUMAN" 2 1596.8372 2.05 114159 9352 3 1596.838116 533.2864 Eukaryotic initiation factor 4A-III OS=Homo sapiens OX=9606 GN=EIF4A3 PE=1 SV=4 8.6 1972.6 - 1.41E+06 - - - 0.5492 - 3.024 0.526 - 494.1 1 2 0 0.0009 15 0 0 0 2.90E+07 1.41E+07 - - - 7.2916 1 221125_WJC_METTL3_EV_vs_WT_F08.09353.09353.3 1.10E-06 14/56 R.STVVDNDADFQGTKR.A sp|Q8IYH5|ZZZ3_HUMAN 1 1651.7802 0.31 114160 9353 3 1651.782155 551.6007 ZZ-type zinc finger-containing protein 3 OS=Homo sapiens OX=9606 GN=ZZZ3 PE=1 SV=1 4.43 1972.7 - 710872 - - - 1.1969 - 2.969 0.535 - 281.6 1 2 0 0.002 15 0 0 0 6.90E+06 2.22E+07 - - - 7.3438 0.9998 221125_WJC_METTL3_EV_vs_WT_F08.09354.09354.4 0.000421 18/78 K.LVSEKVDDYEHAAK.Y "sp|O43148|MCES_HUMAN,tr|K7EP06|K7EP06_HUMAN,tr|K7ERH6|K7ERH6_HUMAN" 3 1602.789 1.19 114161 9354 4 1602.790974 401.7045 mRNA cap guanine-N7 methyltransferase OS=Homo sapiens OX=9606 GN=RNMT PE=1 SV=1 4.75 1972.8 - 692915 - - - 1.2616 - 2.86 0.457 - 232.7 1 2 1 0.002 14 0 0 0 1.43E+07 1.20E+07 - - - 3.5856 0.9999 221125_WJC_METTL3_EV_vs_WT_F08.09362.09362.4 3.29E-05 Dec-78 R.LSASLLHSHDTETR[166.11].A "sp|Q9HCU5|PREB_HUMAN,tr|B5MC98|B5MC98_HUMAN" 2 1575.7881 1.06 114167 9362 4 1575.789632 394.9543 Prolactin regulatory element-binding protein OS=Homo sapiens OX=9606 GN=PREB PE=1 SV=2 5.99 1973.9 - 534522 - - - 1.0014 - 2.344 0.398 - 138.3 1 2 0 0.0016 14 0 0 0 6.48E+06 6.13E+06 - - - 2.9998 0.9983 221125_WJC_METTL3_EV_vs_WT_F08.09364.09364.2 0.016 24-Aug K.SSSQIPAQPSVAK.V "sp|Q9Y520|PRC2C_HUMAN,tr|A0A0A0MS30|A0A0A0MS30_HUMAN,tr|E7EPN9|E7EPN9_HUMAN" 3 1298.683 1.64 114169 9364 2 1298.68538 650.3488 Protein PRRC2C OS=Homo sapiens OX=9606 GN=PRRC2C PE=1 SV=4 8.47 1974.2 - 398463 - - - 1.8095 - 1.554 0.323 - 156.6 1 2 0 0.0024 13 0 0 0 6.66E+06 4.07E+06 - - - 2.5573 0.9993 221125_WJC_METTL3_EV_vs_WT_F08.09366.09366.3 0.0206 Dec-68 K.NKPGPYSSVPPPSAPPPK.K "sp|Q14978|NOLC1_HUMAN,tr|A0A0A0MRM9|A0A0A0MRM9_HUMAN,tr|S4R349|S4R349_HUMAN" 3 1815.9519 3.03 114171 9366 3 1815.950247 606.3246 Nucleolar and coiled-body phosphoprotein 1 OS=Homo sapiens OX=9606 GN=NOLC1 PE=1 SV=2 9.7 1974.4 - 784808 - - - -0.9295 - 2.072 0.292 - 106.6 1 2 0 -0.0017 18 0 0 0 2.04E+07 6.75E+06 - - - 3.6091 1 221125_WJC_METTL3_EV_vs_WT_F08.09367.09367.2 1.88E-06 14/26 K.K[136.11]GPGEVAGTVTGQK[136.11].R "sp|Q86U44|MTA70_HUMAN,tr|F5H6D8|F5H6D8_HUMAN,tr|H0YFV6|H0YFV6_HUMAN,tr|B4DTN4|B4DTN4_HUMAN" 4 1343.738 0.001 114172 9367 2 1343.736025 672.8763 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 8.59 1974.6 - 315519 - - - -1.4542 - 2.843 0.558 - 585.6 1 2 0 -0.002 14 0 0 0 0.00E+00 1.87E+07 - - - 5.7838 0.9993 221125_WJC_METTL3_EV_vs_WT_F08.09371.09371.2 0.000967 28-Jun R.ESSANNSVSPSESLR[166.11].A "sp|Q04726|TLE3_HUMAN,tr|H0YL70|H0YL70_HUMAN,tr|H0YKN8|H0YKN8_HUMAN,tr|H0YKT5|H0YKT5_HUMAN,tr|H0YLW9|H0YLW9_HUMAN,tr|H0YLI3|H0YLI3_HUMAN,tr|H0YKH0|H0YKH0_HUMAN,tr|H0YNT2|H0YNT2_HUMAN" 8 1572.7255 2.93 114176 9371 2 1572.72292 787.37 Transducin-like enhancer protein 3 OS=Homo sapiens OX=9606 GN=TLE3 PE=1 SV=2 4.53 1975.1 - 185339 - - - -1.6487 - 1.571 0.417 - 83.7 1 2 0 -0.0026 15 0 0 0 6.73E+06 2.30E+06 - - - 3.2307 0.9247 221125_WJC_METTL3_EV_vs_WT_F08.09372.09372.2 0.0122 26-May R.SAGLPSHSSVISQH.S sp|P82909|RT36_HUMAN 1 1405.695 - 114177 9372 2 1405.69628 703.8548 "28S ribosomal protein S36, mitochondrial OS=Homo sapiens OX=9606 GN=MRPS36 PE=1 SV=2" 6.66 1975.2 - 135786 - - - 0.9163 - 1.143 0.398 - 68.2 1 1 0 0.0013 14 0 0 0 - - - - - 2.3156 0.9993 221125_WJC_METTL3_EV_vs_WT_F08.09377.09377.3 3.40E-05 Sep-52 K.LVSEK[136.11]VDDYEHAAK[136.11].Y "sp|O43148|MCES_HUMAN,tr|K7EP06|K7EP06_HUMAN,tr|K7ERH6|K7ERH6_HUMAN" 3 1618.8174 1.21 114180 9377 3 1618.821229 540.6131 mRNA cap guanine-N7 methyltransferase OS=Homo sapiens OX=9606 GN=RNMT PE=1 SV=1 4.75 1975.8 - 1.93E+06 - - - 2.395 - 2.149 0.464 - 54.5 1 2 1 0.0039 14 0 0 0 2.43E+07 2.01E+07 - - - 5.7451 0.9999 221125_WJC_METTL3_EV_vs_WT_F08.09378.09378.4 3.11E-07 14/78 K.LVSEK[136.11]VDDYEHAAK[136.11].Y "sp|O43148|MCES_HUMAN,tr|K7EP06|K7EP06_HUMAN,tr|K7ERH6|K7ERH6_HUMAN" 3 1618.8174 1.19 114181 9378 4 1618.820186 405.7116 mRNA cap guanine-N7 methyltransferase OS=Homo sapiens OX=9606 GN=RNMT PE=1 SV=1 4.75 1975.9 - 1.46E+06 - - - 1.7507 - 2.876 0.522 - 99.4 1 2 1 0.0028 14 0 0 0 1.43E+07 1.20E+07 - - - 4.1532 0.9999 221125_WJC_METTL3_EV_vs_WT_F08.09380.09380.3 0.000182 13/52 K.K[136.11]GPGEVAGTVTGQK[136.11].R "sp|Q86U44|MTA70_HUMAN,tr|F5H6D8|F5H6D8_HUMAN,tr|H0YFV6|H0YFV6_HUMAN,tr|B4DTN4|B4DTN4_HUMAN" 4 1343.738 0.01 114183 9380 3 1343.738896 448.9199 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 8.59 1976 - 1.01E+06 - - - 0.6824 - 2.392 0.392 - 242 1 2 0 0.0009 14 0 0 0 1.60E+05 1.97E+07 - - - 5.2279 0.9999 221125_WJC_METTL3_EV_vs_WT_F08.09382.09382.3 2.35E-07 21/76 R.AAAAAATAPPSPGPAQPGPR.A sp|Q6SPF0|SAMD1_HUMAN 1 1754.9064 3.31 114185 9382 3 1754.912261 585.9761 Sterile alpha motif domain-containing protein 1 OS=Homo sapiens OX=9606 GN=SAMD1 PE=1 SV=1 9.79 1976.2 - 668505 - - - 3.3506 - 3.671 0.511 - 616.5 1 2 0 0.0059 20 0 0 0 8.42E+06 2.54E+06 - - - 7.3905 0.9991 221125_WJC_METTL3_EV_vs_WT_F08.09383.09383.3 0.000105 13/64 K.EPPK[136.11]EETAQLTGPEAGR[166.11].K sp|P48634|PRC2A_HUMAN 1 1826.9129 1.41 114186 9383 3 1826.918254 609.9783 Protein PRRC2A OS=Homo sapiens OX=9606 GN=PRRC2A PE=1 SV=3 4.49 1976.3 - 304802 - - - 2.9158 - 2.285 0.469 - 234.2 1 2 1 0.0053 17 0 0 0 5.24E+06 3.72E+06 - - - 5.8551 0.9976 221125_WJC_METTL3_EV_vs_WT_F08.09387.09387.3 0.000224 13/40 K.YFHPPAHLQAK.L "sp|Q9NR56|MBNL1_HUMAN,sp|Q5VZF2|MBNL2_HUMAN,tr|H7C4T5|H7C4T5_HUMAN,tr|Q86VM6|Q86VM6_HUMAN,tr|H7C4Y1|H7C4Y1_HUMAN,tr|A0A0A0MQX8|A0A0A0MQX8_HUMAN,tr|A0A7P0T9I3|A0A7P0T9I3_HUMAN,tr|C9JCX1|C9JCX1_HUMAN,tr|C9JP00|C9JP00_HUMAN,tr|O95205|O95205_HUMAN" 10 1307.6775 1.06 114188 9387 3 1307.680326 436.8998 Muscleblind-like protein 1 OS=Homo sapiens OX=9606 GN=MBNL1 PE=1 SV=2 8.61 1976.9 - 2.34E+06 - - - 2.168 - 2.502 0.188 - 227.5 1 2 0 0.0028 11 0 0 0 4.38E+07 4.12E+07 - - - 3.2405 0.9999 221125_WJC_METTL3_EV_vs_WT_F08.09389.09389.3 1.66E-06 13/48 K.DTHDQLSEPSEVR[166.11].S "sp|Q15149|PLEC_HUMAN,tr|H0YDN1|H0YDN1_HUMAN" 2 1521.6935 10.51 114190 9389 3 1521.697497 508.2384 Plectin OS=Homo sapiens OX=9606 GN=PLEC PE=1 SV=3 4.31 1977 - 2.06E+06 - - - 2.6365 - 2.314 0.523 - 292.7 1 2 0 0.004 13 0 0 0 2.56E+08 2.44E+07 - - - 6.6445 0.9998 221125_WJC_METTL3_EV_vs_WT_F08.09390.09390.3 0.000631 Dec-40 R.SNTENLSQHFR[166.11].K "sp|Q9UHB6|LIMA1_HUMAN,tr|F8VVQ7|F8VVQ7_HUMAN,tr|F8VRN8|F8VRN8_HUMAN,tr|F8VTU2|F8VTU2_HUMAN" 4 1341.6301 1.5 114191 9390 3 1341.63304 448.2173 LIM domain and actin-binding protein 1 OS=Homo sapiens OX=9606 GN=LIMA1 PE=1 SV=1 6.47 1977 - 1.32E+06 - - - 2.1936 - 2.305 0.414 - 268.8 1 2 0 0.0029 11 0 0 0 4.00E+07 2.68E+07 - - - 5.5272 0.9341 221125_WJC_METTL3_EV_vs_WT_F08.09391.09391.3 0.00604 Oct-48 R.QQDANKETQLLEK.E "sp|Q8IWC1|MA7D3_HUMAN,tr|A0A0A0MRP0|A0A0A0MRP0_HUMAN" 2 1543.7842 1.98 114192 9391 3 1543.789996 515.602 MAP7 domain-containing protein 3 OS=Homo sapiens OX=9606 GN=MAP7D3 PE=1 SV=2 4.68 1977.1 - 788560 - - - 3.7538 - 1.913 0.219 - 150.5 1 2 1 0.0058 13 0 0 0 5.38E+07 2.71E+07 - - - 2.7388 0.9962 221125_WJC_METTL3_EV_vs_WT_F08.09392.09392.3 0.000731 Dec-40 R.QQDLHLESPQR.Q sp|Q9H6F5|CCD86_HUMAN 1 1349.6688 0.51 114193 9392 3 1349.670777 450.8969 Coiled-coil domain-containing protein 86 OS=Homo sapiens OX=9606 GN=CCDC86 PE=1 SV=1 5.32 1977.2 - 787078 - - - 1.4818 - 2.248 0.161 - 225.2 1 2 0 0.002 11 0 0 0 8.04E+06 1.58E+07 - - - 2.6356 0.9999 221125_WJC_METTL3_EV_vs_WT_F08.09400.09400.3 0.000249 Nov-40 R.SNTENLSQHFR.K "sp|Q9UHB6|LIMA1_HUMAN,tr|F8VVQ7|F8VVQ7_HUMAN,tr|F8VRN8|F8VRN8_HUMAN,tr|F8VTU2|F8VTU2_HUMAN" 4 1331.6218 1.24 114199 9400 3 1331.624233 444.8812 LIM domain and actin-binding protein 1 OS=Homo sapiens OX=9606 GN=LIMA1 PE=1 SV=1 6.47 1978.3 - 3.10E+06 - - - 1.8068 - 2.476 0.451 - 256.9 1 2 0 0.0024 11 0 0 0 4.13E+07 3.34E+07 - - - 6.1432 1 221125_WJC_METTL3_EV_vs_WT_F08.09402.09402.2 0.000257 23/30 R.HGGGGGGFGGGGFGSR.S sp|P35908|K22E_HUMAN 1 1319.5755 999 114201 9402 2 1319.577572 660.795 "Keratin, type II cytoskeletal 2 epidermal OS=Homo sapiens OX=9606 GN=KRT2 PE=1 SV=2" 9.76 1978.5 - 1.31E+06 - - - 1.5361 - 4.29 0.711 - 786.3 1 2 0 0.002 16 0 0 0 7.74E+08 0.00E+00 - - - 7.8722 0.9974 221125_WJC_METTL3_EV_vs_WT_F08.09408.09408.3 0.00539 Nov-56 K.LKHEDTNLASSTIVK.E "sp|P32121|ARRB2_HUMAN,tr|Q68DZ5|Q68DZ5_HUMAN" 2 1654.889 0.48 114207 9408 3 1654.890555 552.6369 Beta-arrestin-2 OS=Homo sapiens OX=9606 GN=ARRB2 PE=1 SV=2 6.75 1979.1 - 396529 - - - 0.9396 - 2.022 0.305 - 148.5 1 2 1 0.0016 15 0 0 0 3.28E+06 6.80E+06 - - - 3.7772 0.9999 221125_WJC_METTL3_EV_vs_WT_F08.09416.09416.3 4.98E-05 16/60 R.QQSVAHQQSGSELALR.R sp|O95235|KI20A_HUMAN 1 1737.8758 999 114213 9416 3 1737.877319 580.2992 Kinesin-like protein KIF20A OS=Homo sapiens OX=9606 GN=KIF20A PE=1 SV=1 6.75 1980 - 613466 - - - 0.8683 - 2.517 0.377 - 98.8 1 2 0 0.0015 16 0 0 0 3.02E+06 0.00E+00 - - - 5.1112 0.9986 221125_WJC_METTL3_EV_vs_WT_F08.09417.09417.3 0.00461 Dec-56 K.KPPLLDRPGEGSYNR.Y "sp|Q8NEY8|PPHLN_HUMAN,tr|F8VRK2|F8VRK2_HUMAN,tr|F8VWU8|F8VWU8_HUMAN,tr|F8W0Q9|F8W0Q9_HUMAN,tr|F8VPY7|F8VPY7_HUMAN" 5 1697.8849 2.07 114214 9417 3 1697.891189 566.9689 Periphilin-1 OS=Homo sapiens OX=9606 GN=PPHLN1 PE=1 SV=2 8.59 1980.1 - 586217 - - - 3.6934 - 2.199 0.35 - 154.3 1 2 0 0.0063 15 0 0 0 1.27E+08 6.14E+07 - - - 4.4966 1 221125_WJC_METTL3_EV_vs_WT_F08.09418.09418.4 1.47E-07 16/84 K.KPPLLDRPGEGSYNR.Y "sp|Q8NEY8|PPHLN_HUMAN,tr|F8VRK2|F8VRK2_HUMAN,tr|F8VWU8|F8VWU8_HUMAN,tr|F8W0Q9|F8W0Q9_HUMAN,tr|F8VPY7|F8VPY7_HUMAN" 5 1697.8849 1.71 114215 9418 4 1697.887675 425.4785 Periphilin-1 OS=Homo sapiens OX=9606 GN=PPHLN1 PE=1 SV=2 8.59 1980.2 - 545966 - - - 1.6238 - 2.986 0.488 - 215 1 2 0 0.0028 15 0 0 0 7.53E+07 4.40E+07 - - - 3.8642 0.9965 221125_WJC_METTL3_EV_vs_WT_F08.09419.09419.3 0.309 Nov-56 K.K[136.11]PPLLDR[166.11]PGEGSYNR[166.11].Y "sp|Q8NEY8|PPHLN_HUMAN,tr|F8VRK2|F8VRK2_HUMAN,tr|F8VWU8|F8VWU8_HUMAN,tr|F8W0Q9|F8W0Q9_HUMAN,tr|F8VPY7|F8VPY7_HUMAN" 5 1725.9157 2.06 114216 9419 3 1725.916448 576.3125 Periphilin-1 OS=Homo sapiens OX=9606 GN=PPHLN1 PE=1 SV=2 8.59 1980.3 - 543818 - - - 0.4577 - 1.736 0.222 - 141.5 1 2 0 0.0008 15 0 0 0 1.26E+08 6.14E+07 - - - 2.4541 0.9996 221125_WJC_METTL3_EV_vs_WT_F08.09420.09420.2 5.45E-07 20-Nov R.SNTENLSQHFR.K "sp|Q9UHB6|LIMA1_HUMAN,tr|F8VVQ7|F8VVQ7_HUMAN,tr|F8VRN8|F8VRN8_HUMAN,tr|F8VTU2|F8VTU2_HUMAN" 4 1331.6218 1.54 114217 9420 2 1331.625415 666.8182 LIM domain and actin-binding protein 1 OS=Homo sapiens OX=9606 GN=LIMA1 PE=1 SV=1 6.47 1980.4 - 386460 - - - 2.6945 - 2.365 0.532 - 678.4 1 2 0 0.0036 11 0 0 0 3.82E+06 2.49E+06 - - - 5.2978 0.9677 221125_WJC_METTL3_EV_vs_WT_F08.09425.09425.4 0.000104 Dec-78 L.DANTLAEK[136.11]DEFEHK[136.11].R "sp|P0DMV8|HS71A_HUMAN,sp|P0DMV9|HS71B_HUMAN,tr|V9GZ37|V9GZ37_HUMAN,tr|A0A0G2JIW1|A0A0G2JIW1_HUMAN" 4 1661.7868 0.12 114222 9425 4 1661.787839 416.454 Heat shock 70 kDa protein 1A OS=Homo sapiens OX=9606 GN=HSPA1A PE=1 SV=1 4.5 1981.1 - 232150 - - - 0.6373 - 2.511 0.443 - 118.7 1 1 1 0.0011 14 0 0 0 3.08E+06 2.51E+07 - - - 3.4167 0.9999 221125_WJC_METTL3_EV_vs_WT_F08.09428.09428.3 1.41E-07 14/44 R.VREMEEEAEKLK.E "sp|Q86U42|PABP2_HUMAN,tr|A0A7I2V383|A0A7I2V383_HUMAN" 2 1489.7446 1.06 114223 9428 3 1489.746111 497.5888 Polyadenylate-binding protein 2 OS=Homo sapiens OX=9606 GN=PABPN1 PE=1 SV=3 4.65 1981.5 - 1.56E+06 - - - 0.9847 - 2.932 0.572 - 366.6 1 2 2 0.0015 12 0 0 0 2.61E+07 2.45E+07 - - - 7.8985 1 221125_WJC_METTL3_EV_vs_WT_F08.09429.09429.3 1.03E-08 16/60 R.RGPQLVC[160.03]TGSDDGTVK.L sp|Q96DI7|SNR40_HUMAN 1 1688.8152 1.92 114224 9429 3 1688.815017 563.9457 U5 small nuclear ribonucleoprotein 40 kDa protein OS=Homo sapiens OX=9606 GN=SNRNP40 PE=1 SV=1 5.95 1981.6 - 1.40E+06 - - - -0.0983 - 2.846 0.542 - 375.4 1 2 0 -0.0002 16 0 0 0 1.66E+08 8.62E+07 - - - 7.2664 1 221125_WJC_METTL3_EV_vs_WT_F08.09435.09435.2 7.68E-07 13/26 R.GNLGAGNGNLQGPR[166.11].H "sp|P43243|MATR3_HUMAN,tr|D6RE02|D6RE02_HUMAN,tr|B3KM87|B3KM87_HUMAN,tr|A8MXP9|A8MXP9_HUMAN,tr|D6RAY2|D6RAY2_HUMAN,tr|D6R991|D6R991_HUMAN,tr|A0A0R4J2E8|A0A0R4J2E8_HUMAN,tr|D6RAM9|D6RAM9_HUMAN,tr|D6RIA2|D6RIA2_HUMAN,tr|H0Y8T4|H0Y8T4_HUMAN,tr|D6REM6|D6REM6_HUMAN,tr|D6RBI2|D6RBI2_HUMAN" 12 1333.6726 1.8 114230 9435 2 1333.677534 667.8436 Matrin-3 OS=Homo sapiens OX=9606 GN=MATR3 PE=1 SV=2 9.75 1982.2 - 417945 - - - 3.6771 - 2.631 0.584 - 560.1 1 2 0 0.0049 14 0 0 0 1.27E+07 7.06E+06 - - - 5.7804 1 221125_WJC_METTL3_EV_vs_WT_F08.09437.09437.2 2.55E-08 Oct-32 K.ADPDGPEAQAEAC[160.03]SGER[166.11].T "sp|Q9NX24|NHP2_HUMAN,tr|J3QSY4|J3QSY4_HUMAN,tr|D6RCB9|D6RCB9_HUMAN,tr|D6RC52|D6RC52_HUMAN" 4 1768.7198 1.54 114232 9437 2 1768.718596 885.3672 H\ACA ribonucleoprotein complex subunit 2 OS=Homo sapiens OX=9606 GN=NHP2 PE=1 SV=1 3.83 1982.5 - 195127 - - - -0.6671 - 2.544 0.741 - 296.8 1 2 0 -0.0012 17 0 0 0 5.23E+06 3.39E+06 - - - 6.8093 0.9999 221125_WJC_METTL3_EV_vs_WT_F08.09443.09443.3 2.64E-05 14/60 R.R[166.11]GPQLVC[160.03]TGSDDGTVK[136.11].L sp|Q96DI7|SNR40_HUMAN 1 1706.8377 1.92 114236 9443 3 1706.836524 569.9532 U5 small nuclear ribonucleoprotein 40 kDa protein OS=Homo sapiens OX=9606 GN=SNRNP40 PE=1 SV=1 5.95 1983.2 - 2.41E+06 - - - -0.6615 - 2.34 0.461 - 232 1 2 0 -0.0011 16 0 0 0 1.66E+08 8.61E+07 - - - 5.8608 0.9845 221125_WJC_METTL3_EV_vs_WT_F08.09445.09445.3 0.621 Nov-40 R.VKQELLEEVKK.E sp|P50552|VASP_HUMAN 1 1341.7868 2.01 114238 9445 3 1341.78496 448.2695 Vasodilator-stimulated phosphoprotein OS=Homo sapiens OX=9606 GN=VASP PE=1 SV=3 6.2 1983.3 - 1.76E+06 - - - -1.3467 - 1.673 0.232 - 108.9 1 2 1 -0.0018 11 0 0 0 3.72E+07 1.85E+07 - - - 2.588 1 221125_WJC_METTL3_EV_vs_WT_F08.09446.09446.3 4.48E-10 19/48 R.VHQLEDDK[136.11]MDITK[136.11].E "sp|Q15643|TRIPB_HUMAN,tr|H0YJ97|H0YJ97_HUMAN" 2 1586.7945 1.14 114239 9446 3 1586.792892 529.9388 Thyroid receptor-interacting protein 11 OS=Homo sapiens OX=9606 GN=TRIP11 PE=1 SV=3 4.66 1983.4 - 900557 - - - -1.0184 - 3.132 0.618 - 450 1 2 1 -0.0016 13 0 0 0 1.45E+08 1.27E+08 - - - 8.525 0.9946 221125_WJC_METTL3_EV_vs_WT_F08.09451.09451.3 0.000369 15/52 L.DANTLAEK[136.11]DEFEHK[136.11].R "sp|P0DMV8|HS71A_HUMAN,sp|P0DMV9|HS71B_HUMAN,tr|V9GZ37|V9GZ37_HUMAN,tr|A0A0G2JIW1|A0A0G2JIW1_HUMAN" 4 1661.7868 0.13 114241 9451 3 1661.785044 554.9362 Heat shock 70 kDa protein 1A OS=Homo sapiens OX=9606 GN=HSPA1A PE=1 SV=1 4.5 1984.1 - 2.55E+06 - - - -1.0447 - 3.431 0.561 - 247 1 1 1 -0.0017 14 0 0 0 5.10E+06 4.06E+07 - - - 8.0705 0.9974 221125_WJC_METTL3_EV_vs_WT_F08.09453.09453.4 0.00884 13/72 R.VHQLEDDKMDITK.E "sp|Q15643|TRIPB_HUMAN,tr|H0YJ97|H0YJ97_HUMAN" 2 1570.7661 1.24 114243 9453 4 1570.765985 393.6988 Thyroid receptor-interacting protein 11 OS=Homo sapiens OX=9606 GN=TRIP11 PE=1 SV=3 4.66 1984.2 - 1.04E+06 - - - -0.0783 - 2.104 0.315 - 187.1 1 2 1 -0.0001 13 0 0 0 8.51E+07 6.86E+07 - - - 2.2435 0.9988 221125_WJC_METTL3_EV_vs_WT_F08.09455.09455.3 0.00355 13/40 K.VQHVIHYQVPR[166.11].T "sp|Q9GZR7|DDX24_HUMAN,tr|A0A087WXU8|A0A087WXU8_HUMAN,tr|A0A1W2PRR2|A0A1W2PRR2_HUMAN,tr|F5GYL3|F5GYL3_HUMAN,tr|G3V529|G3V529_HUMAN" 5 1384.7603 0.86 114245 9455 3 1384.756287 462.5941 ATP-dependent RNA helicase DDX24 OS=Homo sapiens OX=9606 GN=DDX24 PE=1 SV=1 8.73 1984.5 - 564547 - - - -2.9146 - 1.997 0.323 - 193.5 1 2 0 -0.004 11 0 0 0 1.15E+07 1.33E+07 - - - 4.1049 1 221125_WJC_METTL3_EV_vs_WT_F08.09456.09456.2 3.80E-08 18/30 R.RGPQLVC[160.03]TGSDDGTVK.L sp|Q96DI7|SNR40_HUMAN 1 1688.8152 2.06 114246 9456 2 1688.812717 845.4149 U5 small nuclear ribonucleoprotein 40 kDa protein OS=Homo sapiens OX=9606 GN=SNRNP40 PE=1 SV=1 5.95 1984.6 - 393629 - - - -1.4602 - 3.582 0.656 - 611.2 1 2 0 -0.0025 16 0 0 0 1.33E+07 6.46E+06 - - - 7.0224 1 221125_WJC_METTL3_EV_vs_WT_F08.09460.09460.4 8.69E-07 17/84 K.K[136.11]PPLLDR[166.11]PGEGSYNR[166.11].Y "sp|Q8NEY8|PPHLN_HUMAN,tr|F8VRK2|F8VRK2_HUMAN,tr|F8VWU8|F8VWU8_HUMAN,tr|F8W0Q9|F8W0Q9_HUMAN,tr|F8VPY7|F8VPY7_HUMAN" 5 1725.9157 1.71 114248 9460 4 1725.916448 432.4862 Periphilin-1 OS=Homo sapiens OX=9606 GN=PPHLN1 PE=1 SV=2 8.59 1985.1 - 2.27E+06 - - - 0.4577 - 2.837 0.521 - 282 1 2 0 0.0008 15 0 0 0 7.54E+07 4.40E+07 - - - 4.1337 0.9998 221125_WJC_METTL3_EV_vs_WT_F08.09473.09473.4 4.18E-06 13/72 R.VHQLEDDK[136.11]MDITK[136.11].E "sp|Q15643|TRIPB_HUMAN,tr|H0YJ97|H0YJ97_HUMAN" 2 1586.7945 1.24 114257 9473 4 1586.79104 397.7059 Thyroid receptor-interacting protein 11 OS=Homo sapiens OX=9606 GN=TRIP11 PE=1 SV=3 4.66 1986.6 - 3.31E+06 - - - -2.1855 - 2.292 0.498 - 185.1 1 2 1 -0.0035 13 0 0 0 8.50E+07 6.86E+07 - - - 3.8672 0.9973 221125_WJC_METTL3_EV_vs_WT_F08.09477.09477.4 0.00514 Nov-90 R.SFGTEDR[166.11]PTDR[166.11]PIPPR[166.11].D "sp|Q8ND56|LS14A_HUMAN,tr|I3L4Q1|I3L4Q1_HUMAN,tr|A0A140TA76|A0A140TA76_HUMAN,tr|K7EMZ9|K7EMZ9_HUMAN" 4 1869.9476 1.01 114260 9477 4 1869.944367 468.4942 Protein LSM14 homolog A OS=Homo sapiens OX=9606 GN=LSM14A PE=1 SV=3 5.84 1987 - 1.53E+06 - - - -1.7129 - 1.695 0.265 - 72.4 1 2 0 -0.0032 16 0 0 0 2.38E+08 2.35E+08 - - - 1.7176 1 221125_WJC_METTL3_EV_vs_WT_F08.09478.09478.3 3.82E-08 20/72 R.ILEQEEEEEQAGKPGEPSK.K sp|Q9BXP5|SRRT_HUMAN 1 2126.0015 1.17 114261 9478 3 2126.001979 709.6745 Serrate RNA effector molecule homolog OS=Homo sapiens OX=9606 GN=SRRT PE=1 SV=1 4.12 1987.2 - 1.26E+06 - - - 0.2145 - 3.495 0.617 - 454.4 1 2 0 0.0005 19 0 0 0 1.38E+07 1.18E+07 - - - 8.4931 0.9999 221125_WJC_METTL3_EV_vs_WT_F08.09479.09479.3 3.36E-06 Dec-44 R.YNHPKPNLLYQK.F "sp|Q5T3I0|GPTC4_HUMAN,tr|E9PPY4|E9PPY4_HUMAN,tr|F2Z3C6|F2Z3C6_HUMAN,tr|A0A0A0MRK1|A0A0A0MRK1_HUMAN,tr|E9PAV9|E9PAV9_HUMAN" 5 1513.8041 1.65 114262 9479 3 1513.801202 505.6087 G patch domain-containing protein 4 OS=Homo sapiens OX=9606 GN=GPATCH4 PE=1 SV=2 9.53 1987.3 - 1.14E+06 - - - -1.9461 - 2.121 0.458 - 124.8 1 2 0 -0.0029 12 0 0 0 3.39E+07 2.05E+07 - - - 5.7296 0.9995 221125_WJC_METTL3_EV_vs_WT_F08.09480.09480.3 0.000141 Sep-44 R.YNHPK[136.11]PNLLYQK[136.11].F "sp|Q5T3I0|GPTC4_HUMAN,tr|E9PPY4|E9PPY4_HUMAN,tr|F2Z3C6|F2Z3C6_HUMAN,tr|A0A0A0MRK1|A0A0A0MRK1_HUMAN,tr|E9PAV9|E9PAV9_HUMAN" 5 1529.8325 1.63 114263 9480 3 1529.836898 510.9515 G patch domain-containing protein 4 OS=Homo sapiens OX=9606 GN=GPATCH4 PE=1 SV=2 9.53 1987.4 - 751704 - - - 2.8434 - 2.137 0.381 - 76.7 1 2 0 0.0043 12 0 0 0 3.34E+07 2.05E+07 - - - 4.8915 0.9996 221125_WJC_METTL3_EV_vs_WT_F08.09481.09481.3 0.0028 14/60 R.SFGTEDRPTDRPIPPR.D "sp|Q8ND56|LS14A_HUMAN,tr|I3L4Q1|I3L4Q1_HUMAN,tr|A0A140TA76|A0A140TA76_HUMAN,tr|K7EMZ9|K7EMZ9_HUMAN" 4 1839.9228 1.12 114264 9481 3 1839.920587 614.3149 Protein LSM14 homolog A OS=Homo sapiens OX=9606 GN=LSM14A PE=1 SV=3 5.84 1987.5 - 644680 - - - -1.181 - 1.721 0.371 - 85.4 1 2 0 -0.0022 16 0 0 0 1.18E+08 1.06E+08 - - - 4.0687 1 221125_WJC_METTL3_EV_vs_WT_F08.09483.09483.2 9.39E-06 13/24 R.VHQLEDDK[136.11]MDITK[136.11].E "sp|Q15643|TRIPB_HUMAN,tr|H0YJ97|H0YJ97_HUMAN" 2 1586.7945 0.81 114266 9483 2 1586.793532 794.4045 Thyroid receptor-interacting protein 11 OS=Homo sapiens OX=9606 GN=TRIP11 PE=1 SV=3 4.66 1987.8 - 311469 - - - -0.6151 - 2.644 0.604 - 472.5 1 2 1 -0.001 13 0 0 0 4.25E+06 5.22E+06 - - - 5.9973 0.9997 221125_WJC_METTL3_EV_vs_WT_F08.09486.09486.3 6.88E-05 Dec-48 R.VHQLEDDKMDITK.E "sp|Q15643|TRIPB_HUMAN,tr|H0YJ97|H0YJ97_HUMAN" 2 1570.7661 1.14 114267 9486 3 1570.764061 524.596 Thyroid receptor-interacting protein 11 OS=Homo sapiens OX=9606 GN=TRIP11 PE=1 SV=3 4.66 1988.2 - 7.02E+06 - - - -1.3032 - 2.121 0.454 - 203.8 1 2 1 -0.002 13 0 0 0 1.45E+08 1.27E+08 - - - 5.6397 0.9661 221125_WJC_METTL3_EV_vs_WT_F08.09487.09487.4 0.23 Oct-90 R.SFGTEDRPTDRPIPPR.D "sp|Q8ND56|LS14A_HUMAN,tr|I3L4Q1|I3L4Q1_HUMAN,tr|A0A140TA76|A0A140TA76_HUMAN,tr|K7EMZ9|K7EMZ9_HUMAN" 4 1839.9228 1.01 114268 9487 4 1839.922283 460.988 Protein LSM14 homolog A OS=Homo sapiens OX=9606 GN=LSM14A PE=1 SV=3 5.84 1988.3 - 2.26E+06 - - - -0.2593 - 1.452 0.16 - 58.7 1 2 0 -0.0005 16 0 0 0 2.38E+08 2.35E+08 - - - 0.7499 1 221125_WJC_METTL3_EV_vs_WT_F08.09489.09489.3 1.27E-07 15/56 R.TPTQTNGSNVPFKPR.G "sp|P78347|GTF2I_HUMAN,tr|A0A494C1K3|A0A494C1K3_HUMAN" 2 1642.8427 1.6 114270 9489 3 1642.84244 548.6215 General transcription factor II-I OS=Homo sapiens OX=9606 GN=GTF2I PE=1 SV=2 11 1988.4 - 1.29E+06 - - - -0.1692 - 2.663 0.582 - 191.5 1 2 0 -0.0003 15 0 0 0 2.00E+09 1.25E+09 - - - 7.5844 1 221125_WJC_METTL3_EV_vs_WT_F08.09490.09490.3 1.46E-06 15/60 R.SFGTEDR[166.11]PTDR[166.11]PIPPR[166.11].D "sp|Q8ND56|LS14A_HUMAN,tr|I3L4Q1|I3L4Q1_HUMAN,tr|A0A140TA76|A0A140TA76_HUMAN,tr|K7EMZ9|K7EMZ9_HUMAN" 4 1869.9476 1.12 114271 9490 3 1869.946805 624.3231 Protein LSM14 homolog A OS=Homo sapiens OX=9606 GN=LSM14A PE=1 SV=3 5.84 1988.5 - 1.12E+06 - - - -0.4091 - 2.23 0.529 - 111.2 1 2 0 -0.0008 16 0 0 0 1.18E+08 1.06E+08 - - - 6.4954 1 221125_WJC_METTL3_EV_vs_WT_F08.09491.09491.3 2.70E-06 16/52 K.GIGTLHLK[136.11]PTANQK[136.11].T "sp|Q9UKX7|NUP50_HUMAN,tr|B0QY21|B0QY21_HUMAN" 2 1492.8697 1.2 114272 9491 3 1492.868683 498.6305 Nuclear pore complex protein Nup50 OS=Homo sapiens OX=9606 GN=NUP50 PE=1 SV=2 10 1988.7 - 673279 - - - -0.6558 - 2.344 0.474 - 163.7 1 2 0 -0.001 14 0 0 0 4.10E+07 3.40E+07 - - - 6.0882 1 221125_WJC_METTL3_EV_vs_WT_F08.09495.09495.3 0.000415 18/56 R.TPTQTNGSNVPFK[136.11]PR[166.11].G "sp|P78347|GTF2I_HUMAN,tr|A0A494C1K3|A0A494C1K3_HUMAN" 2 1660.8652 1.6 114274 9495 3 1660.864239 554.629 General transcription factor II-I OS=Homo sapiens OX=9606 GN=GTF2I PE=1 SV=2 11 1989.2 - 2.92E+06 - - - -0.5714 - 3.431 0.587 - 283.1 1 2 0 -0.0009 15 0 0 0 2.00E+09 1.25E+09 - - - 8.3012 0.9998 221125_WJC_METTL3_EV_vs_WT_F08.09496.09496.4 0.000487 15/72 K.MNGINRPLIKPQR.R "sp|P43694|GATA4_HUMAN,tr|E9PKS4|E9PKS4_HUMAN,tr|B3KUF4|B3KUF4_HUMAN,tr|A0A087WZ09|A0A087WZ09_HUMAN" 4 1535.8719 2.15 114275 9496 4 1535.870792 384.9752 Transcription factor GATA-4 OS=Homo sapiens OX=9606 GN=GATA4 PE=1 SV=2 12.01 1989.3 - 480001 - - - -0.6895 - 2.124 0.376 - 153.4 1 2 0 -0.0011 13 0 0 0 1.76E+07 8.20E+06 - - - 2.7777 0.9995 221125_WJC_METTL3_EV_vs_WT_F08.09499.09499.3 0.00068 Aug-52 K.THSTTSQAISVGMR[166.11].M "sp|Q9BQ52|RNZ2_HUMAN,tr|G5E9D5|G5E9D5_HUMAN,tr|E7ES68|E7ES68_HUMAN" 3 1484.7281 0.5 114278 9499 3 1484.727504 495.9166 Zinc phosphodiesterase ELAC protein 2 OS=Homo sapiens OX=9606 GN=ELAC2 PE=1 SV=2 9.44 1989.6 - 899536 - - - -0.3987 - 2.084 0.305 - 82.8 1 2 0 -0.0006 14 0 0 0 7.12E+06 1.44E+07 - - - 3.8917 0.8633 221125_WJC_METTL3_EV_vs_WT_F08.09500.09500.3 0.766 Oct-48 K.IQDKEGIPPDQQR.L "sp|P62979|RS27A_HUMAN,sp|P0CG48|UBC_HUMAN,sp|P0CG48|UBC_HUMAN,sp|P0CG48|UBC_HUMAN,sp|P0CG48|UBC_HUMAN,sp|P0CG48|UBC_HUMAN,sp|P0CG48|UBC_HUMAN,sp|P0CG48|UBC_HUMAN,sp|P0CG48|UBC_HUMAN,sp|P0CG48|UBC_HUMAN,sp|P0CG47|UBB_HUMAN,sp|P0CG47|UBB_HUMAN,sp|P0CG47|UBB_HUMAN,sp|P62987|RL40_HUMAN,tr|F5H388|F5H388_HUMAN,tr|F5H388|F5H388_HUMAN,tr|F5GYU3|F5GYU3_HUMAN,tr|F5GYU3|F5GYU3_HUMAN,tr|B4DV12|B4DV12_HUMAN,tr|B4DV12|B4DV12_HUMAN,tr|J3QSA3|J3QSA3_HUMAN,tr|Q5PY61|Q5PY61_HUMAN,tr|Q5PY61|Q5PY61_HUMAN,tr|Q5PY61|Q5PY61_HUMAN,tr|F5H2Z3|F5H2Z3_HUMAN,tr|F5H2Z3|F5H2Z3_HUMAN,tr|M0R2S1|M0R2S1_HUMAN,tr|J3QS39|J3QS39_HUMAN,tr|J3QTR3|J3QTR3_HUMAN,tr|Q96C32|Q96C32_HUMAN,tr|Q96C32|Q96C32_HUMAN,tr|Q96C32|Q96C32_HUMAN,tr|Q96C32|Q96C32_HUMAN,tr|M0R1V7|M0R1V7_HUMAN,tr|F5H747|F5H747_HUMAN,tr|F5H747|F5H747_HUMAN,tr|F5GXK7|F5GXK7_HUMAN,tr|F5GXK7|F5GXK7_HUMAN,tr|M0R1M6|M0R1M6_HUMAN,tr|F5H6Q2|F5H6Q2_HUMAN,tr|F5H6Q2|F5H6Q2_HUMAN,tr|F5GZ39|F5GZ39_HUMAN,tr|J3QKN0|J3QKN0_HUMAN,tr|J3QKN0|J3QKN0_HUMAN,tr|F5H265|F5H265_HUMAN,tr|F5H265|F5H265_HUMAN,tr|A0A2R8Y422|A0A2R8Y422_HUMAN" 47 1522.774 0.83 114279 9500 3 1522.769654 508.5986 Ubiquitin-40S ribosomal protein S27a OS=Homo sapiens OX=9606 GN=RPS27A PE=1 SV=2 4.56 1989.7 - 582758 - - - -2.8343 - 1.88 0.138 - 161.6 1 2 1 -0.0043 13 0 0 0 1.36E+07 1.65E+07 - - - 1.7889 1 221125_WJC_METTL3_EV_vs_WT_F08.09501.09501.3 3.49E-09 13/72 R.ILEQEEEEEQAGK[136.11]PGEPSK[136.11].K sp|Q9BXP5|SRRT_HUMAN 1 2142.0299 1.17 114280 9501 3 2142.029547 715.0173 Serrate RNA effector molecule homolog OS=Homo sapiens OX=9606 GN=SRRT PE=1 SV=1 4.12 1989.9 - 528240 - - - -0.1755 - 2.728 0.523 - 158.3 1 2 0 -0.0004 19 0 0 0 1.38E+07 1.18E+07 - - - 6.8364 0.9999 221125_WJC_METTL3_EV_vs_WT_F08.09504.09504.3 0.002 Dec-44 R.RTEEGPTLSYGR.D "sp|P43243|MATR3_HUMAN,tr|A8MXP9|A8MXP9_HUMAN,tr|D6R991|D6R991_HUMAN,tr|A0A0R4J2E8|A0A0R4J2E8_HUMAN,tr|D6REM6|D6REM6_HUMAN" 5 1364.6684 1.34 114281 9504 3 1364.669017 455.8968 Matrin-3 OS=Homo sapiens OX=9606 GN=MATR3 PE=1 SV=2 6.14 1990.3 - 1.68E+06 - - - 0.4213 - 2.291 0.383 - 247.1 1 2 0 0.0006 12 0 0 0 2.73E+08 2.05E+08 - - - 5.1077 0.9995 221125_WJC_METTL3_EV_vs_WT_F08.09505.09505.3 7.38E-07 15/56 R.RATTGTQTLLSSGTR.L "sp|Q8IX01|SUGP2_HUMAN,tr|M0R2Z9|M0R2Z9_HUMAN,tr|M0R3F6|M0R3F6_HUMAN" 3 1548.822 1.04 114282 9505 3 1548.830421 517.2813 SURP and G-patch domain-containing protein 2 OS=Homo sapiens OX=9606 GN=SUGP2 PE=1 SV=2 12 1990.4 - 791647 - - - 5.448 - 2.87 0.496 - 259 1 2 0 0.0084 15 0 0 0 8.38E+06 8.07E+06 - - - 6.8187 0.8699 221125_WJC_METTL3_EV_vs_WT_F08.09507.09507.4 1.75 Aug-66 R.YNHPK[136.11]PNLLYQK[136.11].F "sp|Q5T3I0|GPTC4_HUMAN,tr|E9PPY4|E9PPY4_HUMAN,tr|F2Z3C6|F2Z3C6_HUMAN,tr|A0A0A0MRK1|A0A0A0MRK1_HUMAN,tr|E9PAV9|E9PAV9_HUMAN" 5 1529.8325 0.02 114284 9507 4 1529.83197 383.4654 G patch domain-containing protein 4 OS=Homo sapiens OX=9606 GN=GPATCH4 PE=1 SV=2 9.53 1990.5 - 873049 - - - -0.3778 - 1.377 0.109 - 32.4 1 2 0 -0.0006 12 0 0 0 2.45E+05 1.21E+07 - - - 0.2956 0.9922 221125_WJC_METTL3_EV_vs_WT_F08.09508.09508.3 0.000253 13/52 F.GTEDRPTDRPIPPR.D "sp|Q8ND56|LS14A_HUMAN,tr|I3L4Q1|I3L4Q1_HUMAN,tr|A0A140TA76|A0A140TA76_HUMAN,tr|K7EMZ9|K7EMZ9_HUMAN" 4 1605.8223 1.15 114285 9508 3 1605.823615 536.2814 Protein LSM14 homolog A OS=Homo sapiens OX=9606 GN=LSM14A PE=1 SV=3 6.12 1990.7 - 427396 - - - 0.8083 - 2.361 0.419 - 106.1 1 1 0 0.0013 14 0 0 0 6.20E+06 5.39E+06 - - - 5.4941 0.9969 221125_WJC_METTL3_EV_vs_WT_F08.09509.09509.2 0.000105 13/24 R.VHQLEDDKMDITK.E "sp|Q15643|TRIPB_HUMAN,tr|H0YJ97|H0YJ97_HUMAN" 2 1570.7661 0.81 114286 9509 2 1570.763951 786.3903 Thyroid receptor-interacting protein 11 OS=Homo sapiens OX=9606 GN=TRIP11 PE=1 SV=3 4.66 1990.8 - 288564 - - - -1.3732 - 1.787 0.487 - 297.6 1 2 1 -0.0022 13 0 0 0 4.25E+06 5.22E+06 - - - 4.1273 0.9998 221125_WJC_METTL3_EV_vs_WT_F08.09516.09516.3 9.73E-06 Nov-52 K.GIGTLHLKPTANQK.T "sp|Q9UKX7|NUP50_HUMAN,tr|B0QY21|B0QY21_HUMAN" 2 1476.8413 1.2 114291 9516 3 1476.84503 493.2877 Nuclear pore complex protein Nup50 OS=Homo sapiens OX=9606 GN=NUP50 PE=1 SV=2 10 1991.5 - 2.72E+06 - - - 2.5514 - 2.285 0.432 - 92.5 1 2 0 0.0038 14 0 0 0 4.10E+07 3.40E+07 - - - 5.5514 0.9993 221125_WJC_METTL3_EV_vs_WT_F08.09518.09518.3 0.00192 Dec-36 K.EIEEYIHK[136.11]PK[136.11].Y sp|P42285|MTREX_HUMAN 1 1300.6998 0.66 114293 9518 3 1300.700606 434.5739 Exosome RNA helicase MTR4 OS=Homo sapiens OX=9606 GN=MTREX PE=1 SV=3 5.5 1991.7 - 758087 - - - 0.6174 - 1.965 0.275 - 189.4 1 2 0 0.0008 10 0 0 0 1.93E+07 2.94E+07 - - - 3.5785 1 221125_WJC_METTL3_EV_vs_WT_F08.09520.09520.2 3.07E-09 28-Dec R.TPTQTNGSNVPFKPR.G "sp|P78347|GTF2I_HUMAN,tr|A0A494C1K3|A0A494C1K3_HUMAN" 2 1642.8427 1.62 114295 9520 2 1642.840958 822.4286 General transcription factor II-I OS=Homo sapiens OX=9606 GN=GTF2I PE=1 SV=2 11 1991.9 - 266013 - - - -1.0713 - 2.576 0.63 - 332.4 1 2 0 -0.0018 15 0 0 0 5.67E+07 3.51E+07 - - - 6.02 0.9994 221125_WJC_METTL3_EV_vs_WT_F08.09526.09526.3 0.000196 Nov-44 K.SK[136.11]QGLDSFDTGK[136.11].G "sp|Q14241|ELOA1_HUMAN,tr|A0A024RAC6|A0A024RAC6_HUMAN" 2 1297.6485 0.59 114299 9526 3 1297.649578 433.5568 Elongin-A OS=Homo sapiens OX=9606 GN=ELOA PE=1 SV=2 5.68 1992.7 - 739410 - - - 0.8346 - 2.095 0.389 - 159 1 2 1 0.0011 12 0 0 0 1.18E+07 2.02E+07 - - - 4.9266 0.9998 221125_WJC_METTL3_EV_vs_WT_F08.09527.09527.2 0.00262 22-Nov R.RTEEGPTLSYGR.D "sp|P43243|MATR3_HUMAN,tr|A8MXP9|A8MXP9_HUMAN,tr|D6R991|D6R991_HUMAN,tr|A0A0R4J2E8|A0A0R4J2E8_HUMAN,tr|D6REM6|D6REM6_HUMAN" 5 1364.6684 1.43 114300 9527 2 1364.669023 683.3415 Matrin-3 OS=Homo sapiens OX=9606 GN=MATR3 PE=1 SV=2 6.14 1992.8 - 689044 - - - 0.4257 - 2.391 0.427 - 74 1 2 0 0.0006 12 0 0 0 3.68E+07 2.57E+07 - - - 4.4883 0.9999 221125_WJC_METTL3_EV_vs_WT_F08.09529.09529.2 1.15E-05 15/22 R.R[166.11]TEEGPTLSYGR[166.11].D "sp|P43243|MATR3_HUMAN,tr|A8MXP9|A8MXP9_HUMAN,tr|D6R991|D6R991_HUMAN,tr|A0A0R4J2E8|A0A0R4J2E8_HUMAN,tr|D6REM6|D6REM6_HUMAN" 5 1384.685 1.43 114302 9529 2 1384.685952 693.3498 Matrin-3 OS=Homo sapiens OX=9606 GN=MATR3 PE=1 SV=2 6.14 1993.1 - 495786 - - - 0.7005 - 2.347 0.555 - 215.1 1 2 0 0.001 12 0 0 0 3.68E+07 2.57E+07 - - - 5.3847 1 221125_WJC_METTL3_EV_vs_WT_F08.09530.09530.3 9.19E-05 17/52 R.K[136.11]NPLPPSVGVVDK[136.11]K[136.11].E sp|Q8NC51|PAIRB_HUMAN 1 1500.909 0.58 114303 9530 3 1500.909752 501.3103 Plasminogen activator inhibitor 1 RNA-binding protein OS=Homo sapiens OX=9606 GN=SERBP1 PE=1 SV=2 9.7 1993.2 - 433966 - - - 0.4917 - 3.366 0.55 - 417 1 2 0 0.0007 14 0 0 0 2.12E+07 3.64E+07 - - - 7.8973 1 221125_WJC_METTL3_EV_vs_WT_F08.09531.09531.2 3.34E-09 14/28 R.TPTQTNGSNVPFK[136.11]PR[166.11].G "sp|P78347|GTF2I_HUMAN,tr|A0A494C1K3|A0A494C1K3_HUMAN" 2 1660.8652 1.62 114304 9531 2 1660.866328 831.4399 General transcription factor II-I OS=Homo sapiens OX=9606 GN=GTF2I PE=1 SV=2 11 1993.3 - 294535 - - - 0.6864 - 2.947 0.581 - 538.1 1 2 0 0.0011 15 0 0 0 5.67E+07 3.50E+07 - - - 5.9891 1 221125_WJC_METTL3_EV_vs_WT_F08.09532.09532.3 5.20E-05 20/64 R.VLEVASGSGQHAAHFAR.A "sp|Q96S19|MTL26_HUMAN,tr|A0A087WYU2|A0A087WYU2_HUMAN,tr|H3BNT3|H3BNT3_HUMAN,tr|H3BRT2|H3BRT2_HUMAN,tr|H3BNB2|H3BNB2_HUMAN,tr|H3BS73|H3BS73_HUMAN,tr|H3BMF3|H3BMF3_HUMAN,tr|H3BQ55|H3BQ55_HUMAN" 8 1735.8754 1.4 114305 9532 3 1735.880231 579.6324 Methyltransferase-like 26 OS=Homo sapiens OX=9606 GN=METTL26 PE=1 SV=2 6.89 1993.5 - 258446 - - - 2.7738 - 3.509 0.528 - 502 1 2 0 0.0048 17 0 0 0 1.73E+07 1.23E+07 - - - 7.5967 1 221125_WJC_METTL3_EV_vs_WT_F08.09538.09538.4 2.79E-05 17/96 R.VLEVASGSGQHAAHFAR.A "sp|Q96S19|MTL26_HUMAN,tr|A0A087WYU2|A0A087WYU2_HUMAN,tr|H3BNT3|H3BNT3_HUMAN,tr|H3BRT2|H3BRT2_HUMAN,tr|H3BNB2|H3BNB2_HUMAN,tr|H3BS73|H3BS73_HUMAN,tr|H3BMF3|H3BMF3_HUMAN,tr|H3BQ55|H3BQ55_HUMAN" 8 1735.8754 1.86 114309 9538 4 1735.874918 434.9761 Methyltransferase-like 26 OS=Homo sapiens OX=9606 GN=METTL26 PE=1 SV=2 6.89 1994.2 - 1.15E+06 - - - -0.2869 - 3.546 0.492 - 236.1 1 2 0 -0.0005 17 0 0 0 2.74E+07 1.48E+07 - - - 3.9477 0.9501 221125_WJC_METTL3_EV_vs_WT_F08.09541.09541.3 0.00596 13/52 F.GTEDR[166.11]PTDR[166.11]PIPPR[166.11].D "sp|Q8ND56|LS14A_HUMAN,tr|I3L4Q1|I3L4Q1_HUMAN,tr|A0A140TA76|A0A140TA76_HUMAN,tr|K7EMZ9|K7EMZ9_HUMAN" 4 1635.8471 1.22 114312 9541 3 1635.845218 546.2897 Protein LSM14 homolog A OS=Homo sapiens OX=9606 GN=LSM14A PE=1 SV=3 6.12 1994.6 - 379761 - - - -1.167 - 2.168 0.295 - 104.2 1 1 0 -0.0019 14 0 0 0 1.36E+07 1.12E+07 - - - 3.8848 1 221125_WJC_METTL3_EV_vs_WT_F08.09545.09545.2 3.84E-09 15/42 K.EAAGAGAGPGGDVGAPEADGC[160.03]K.G sp|Q9UJU5|FOXD3_HUMAN 1 1912.8221 1.33 114316 9545 2 1912.822632 957.4183 Forkhead box protein D3 OS=Homo sapiens OX=9606 GN=FOXD3 PE=1 SV=1 3.92 1995.1 - 192009 - - - 0.2682 - 3.104 0.751 - 349.5 1 2 0 0.0005 22 0 0 0 4.47E+06 3.35E+06 - - - 7.3725 1 221125_WJC_METTL3_EV_vs_WT_F08.09547.09547.3 4.09E-08 16/60 R.HGGGGGGFGGGGFGSR.S sp|P35908|K22E_HUMAN 1 1319.5755 5658.41 114317 9547 3 1319.575892 440.8658 "Keratin, type II cytoskeletal 2 epidermal OS=Homo sapiens OX=9606 GN=KRT2 PE=1 SV=2" 9.76 1995.3 - 2.63E+06 - - - 0.263 - 2.383 0.63 - 206.5 1 2 0 0.0003 16 0 0 0 5.01E+09 8.85E+05 - - - 7.7919 1 221125_WJC_METTL3_EV_vs_WT_F08.09553.09553.3 7.74E-10 18/60 K.VDDEPMDVDKGPGSTK.E "sp|Q13123|RED_HUMAN,tr|A0A0C4DGW5|A0A0C4DGW5_HUMAN" 2 1688.7563 1.41 114322 9553 3 1688.754288 563.9261 Protein Red OS=Homo sapiens OX=9606 GN=IK PE=1 SV=3 4.04 1995.8 - 935500 - - - -1.2098 - 3.384 0.672 - 467.4 1 2 1 -0.002 16 0 0 0 2.28E+07 1.61E+07 - - - 9.1595 0.9999 221125_WJC_METTL3_EV_vs_WT_F08.09555.09555.3 8.77E-07 14/56 R.TPTQTNGSNVPFKPR[166.11].G "sp|P78347|GTF2I_HUMAN,tr|A0A494C1K3|A0A494C1K3_HUMAN" 2 1652.851 - 114324 9555 3 1652.855029 551.9576 General transcription factor II-I OS=Homo sapiens OX=9606 GN=GTF2I PE=1 SV=2 11 1995.9 - 703733 - - - 2.4449 - 2.512 0.526 - 182.6 1 2 0 0.004 15 0 0 0 - - - - - 6.8067 0.9889 221125_WJC_METTL3_EV_vs_WT_F08.09556.09556.3 0.000512 Nov-84 K.EAAGAGAGPGGDVGAPEADGC[160.03]K[136.11].G sp|Q9UJU5|FOXD3_HUMAN 1 1920.8363 0.76 114325 9556 3 1921.844498 641.286 Forkhead box protein D3 OS=Homo sapiens OX=9606 GN=FOXD3 PE=1 SV=1 3.92 1996.1 - 416825 - - - 524.8646 - 2.249 0.42 - 89.8 1 2 0 1.0082 22 0 0 0 3.81E+06 5.03E+06 - - - 4.8648 1 221125_WJC_METTL3_EV_vs_WT_F08.09561.09561.3 3.27E-06 13/56 R.SFGGGC[160.03]HVTAAVSSR[166.11].R "sp|Q9NRA8|4ET_HUMAN,tr|B1AKL5|B1AKL5_HUMAN,tr|B1AKL4|B1AKL4_HUMAN" 3 1501.6971 1.27 114328 9561 3 1501.696589 501.573 Eukaryotic translation initiation factor 4E transporter OS=Homo sapiens OX=9606 GN=EIF4ENIF1 PE=1 SV=2 7.99 1996.7 - 933918 - - - -0.3609 - 2.585 0.552 - 142.1 1 2 0 -0.0005 15 0 0 0 4.78E+07 3.75E+07 - - - 7.1723 0.9995 221125_WJC_METTL3_EV_vs_WT_F08.09562.09562.4 7.69E-05 Nov-78 K.VVHLGDKEQSNWAK.E "sp|Q8IZH2|XRN1_HUMAN,tr|H7C5E4|H7C5E4_HUMAN" 2 1609.8213 1.11 114329 9562 4 1609.821324 403.4626 5'-3' exoribonuclease 1 OS=Homo sapiens OX=9606 GN=XRN1 PE=1 SV=1 6.72 1996.9 - 601518 - - - 0.0429 - 2.462 0.408 - 74.4 1 2 1 0.0001 14 0 0 0 3.83E+07 3.45E+07 - - - 3.1051 0.9997 221125_WJC_METTL3_EV_vs_WT_F08.09563.09563.2 1.10E-05 22-Dec K.RYELPAPSSGQK.N sp|O75934|SPF27_HUMAN 1 1331.6834 1.85 114330 9563 2 1331.68078 666.849 Pre-mRNA-splicing factor SPF27 OS=Homo sapiens OX=9606 GN=BCAS2 PE=1 SV=1 8.59 1997 - 243300 - - - -1.9404 - 2.272 0.491 - 303.8 1 2 0 -0.0026 12 0 0 0 1.42E+07 7.68E+06 - - - 4.826 1 221125_WJC_METTL3_EV_vs_WT_F08.09567.09567.4 1.91E-07 16/96 R.VLEVASGSGQHAAHFAR[166.11].A "sp|Q96S19|MTL26_HUMAN,tr|A0A087WYU2|A0A087WYU2_HUMAN,tr|H3BNT3|H3BNT3_HUMAN,tr|H3BRT2|H3BRT2_HUMAN,tr|H3BNB2|H3BNB2_HUMAN,tr|H3BS73|H3BS73_HUMAN,tr|H3BMF3|H3BMF3_HUMAN,tr|H3BQ55|H3BQ55_HUMAN" 8 1745.8837 1.86 114332 9567 4 1745.881182 437.4782 Methyltransferase-like 26 OS=Homo sapiens OX=9606 GN=METTL26 PE=1 SV=2 6.89 1997.5 - 926879 - - - -1.4342 - 2.9 0.509 - 236.2 1 2 0 -0.0025 17 0 0 0 2.74E+07 1.48E+07 - - - 4.0253 0.9995 221125_WJC_METTL3_EV_vs_WT_F08.09570.09570.3 1.02E-05 16/52 K.VVHLGDK[136.11]EQSNWAK[136.11].E "sp|Q8IZH2|XRN1_HUMAN,tr|H7C5E4|H7C5E4_HUMAN" 2 1625.8497 1.02 114335 9570 3 1625.853087 542.9572 5'-3' exoribonuclease 1 OS=Homo sapiens OX=9606 GN=XRN1 PE=1 SV=1 6.72 1997.8 - 766235 - - - 2.1109 - 2.959 0.406 - 344.3 1 2 1 0.0034 14 0 0 0 4.03E+07 3.94E+07 - - - 5.9486 0.9999 221125_WJC_METTL3_EV_vs_WT_F08.09571.09571.3 8.16E-08 18/52 K.VVHLGDKEQSNWAK.E "sp|Q8IZH2|XRN1_HUMAN,tr|H7C5E4|H7C5E4_HUMAN" 2 1609.8213 1.09 114336 9571 3 1609.82461 537.6144 5'-3' exoribonuclease 1 OS=Homo sapiens OX=9606 GN=XRN1 PE=1 SV=1 6.72 1997.9 - 707261 - - - 2.0841 - 2.935 0.549 - 462.8 1 2 1 0.0034 14 0 0 0 4.03E+07 3.69E+07 - - - 7.5213 1 221125_WJC_METTL3_EV_vs_WT_F08.09575.09575.3 0.000121 Nov-56 R.SFGGGC[160.03]HVTAAVSSR.R "sp|Q9NRA8|4ET_HUMAN,tr|B1AKL5|B1AKL5_HUMAN,tr|B1AKL4|B1AKL4_HUMAN" 3 1491.6889 1.27 114338 9575 3 1491.687962 498.2369 Eukaryotic translation initiation factor 4E transporter OS=Homo sapiens OX=9606 GN=EIF4ENIF1 PE=1 SV=2 7.99 1998.5 - 2.04E+06 - - - -0.6027 - 2.24 0.497 - 82.6 1 2 0 -0.0009 15 0 0 0 4.76E+07 3.75E+07 - - - 6.1852 0.9999 221125_WJC_METTL3_EV_vs_WT_F08.09578.09578.2 0.000294 16/28 K.QGGGGGGGSVPGIER[166.11].M "sp|P52272|HNRPM_HUMAN,tr|M0R019|M0R019_HUMAN,tr|A0A087X0X3|A0A087X0X3_HUMAN,tr|M0R2T0|M0R2T0_HUMAN" 4 1293.6301 1.82 114341 9578 2 1293.631496 647.8223 Heterogeneous nuclear ribonucleoprotein M OS=Homo sapiens OX=9606 GN=HNRNPM PE=1 SV=3 6 1998.8 - 265946 - - - 1.0815 - 3.158 0.463 - 705.6 1 2 0 0.0014 15 0 0 0 2.29E+07 1.25E+07 - - - 5.2875 0.9999 221125_WJC_METTL3_EV_vs_WT_F08.09579.09579.2 7.61E-05 Sep-42 K.EAAGAGAGPGGDVGAPEADGC[160.03]K[136.11].G sp|Q9UJU5|FOXD3_HUMAN 1 1920.8363 1.33 114342 9579 2 1920.835385 961.4254 Forkhead box protein D3 OS=Homo sapiens OX=9606 GN=FOXD3 PE=1 SV=1 3.92 1998.9 - 224994 - - - -0.4862 - 1.901 0.604 - 116.3 1 2 0 -0.0009 22 0 0 0 4.47E+06 3.35E+06 - - - 5.0812 1 221125_WJC_METTL3_EV_vs_WT_F08.09584.09584.3 5.23E-08 17/52 R.KAALEAQNALHNMK.V "sp|Q92879|CELF1_HUMAN,tr|G5EA30|G5EA30_HUMAN,tr|E9PSH0|E9PSH0_HUMAN,tr|E9PQK4|E9PQK4_HUMAN,tr|E9PKU1|E9PKU1_HUMAN" 5 1537.8035 2.7 114345 9584 3 1537.803468 513.6084 CUGBP Elav-like family member 1 OS=Homo sapiens OX=9606 GN=CELF1 PE=1 SV=2 8.6 1999.5 - 1.62E+06 - - - -0.0182 - 3.451 0.42 - 334.4 1 2 0 0 14 0 0 0 5.21E+07 1.93E+07 - - - 6.5144 0.9999 221125_WJC_METTL3_EV_vs_WT_F08.09585.09585.4 1.91E-06 14/78 K.VVHLGDK[136.11]EQSNWAK[136.11].E "sp|Q8IZH2|XRN1_HUMAN,tr|H7C5E4|H7C5E4_HUMAN" 2 1625.8497 1.14 114346 9585 4 1625.849824 407.4697 5'-3' exoribonuclease 1 OS=Homo sapiens OX=9606 GN=XRN1 PE=1 SV=1 6.72 1999.6 - 1.79E+06 - - - 0.1039 - 2.331 0.515 - 147.2 1 2 1 0.0002 14 0 0 0 3.83E+07 3.35E+07 - - - 4.0165 0.999 221125_WJC_METTL3_EV_vs_WT_F08.09586.09586.2 2.23E-05 13/20 K.DKDAYSSFGSR.S "sp|O00571|DDX3X_HUMAN,sp|O15523|DDX3Y_HUMAN,tr|A0A2R8YFR4|A0A2R8YFR4_HUMAN,tr|A0A2R8YCW1|A0A2R8YCW1_HUMAN,tr|A0A2R8YDH3|A0A2R8YDH3_HUMAN,tr|A0A2R8Y645|A0A2R8Y645_HUMAN,tr|A0A2R8YF78|A0A2R8YF78_HUMAN,tr|C9J8G5|C9J8G5_HUMAN,tr|A0A2R8YCU0|A0A2R8YCU0_HUMAN,tr|A0A0D9SFB3|A0A0D9SFB3_HUMAN,tr|A0A2R8YFS5|A0A2R8YFS5_HUMAN,tr|A0A0D9SF53|A0A0D9SF53_HUMAN,tr|A0A2R8Y650|A0A2R8Y650_HUMAN,tr|A0A087WX09|A0A087WX09_HUMAN,tr|C9J081|C9J081_HUMAN,tr|A0A2R8Y5G6|A0A2R8Y5G6_HUMAN,tr|A0A0D9SG12|A0A0D9SG12_HUMAN,tr|F6S8Q4|F6S8Q4_HUMAN,tr|A0A2U3TZJ9|A0A2U3TZJ9_HUMAN,tr|A0A2R8Y4A4|A0A2R8Y4A4_HUMAN,tr|A0A2R8YF89|A0A2R8YF89_HUMAN" 21 1231.5469 1.13 114347 9586 2 1231.546459 616.7807 ATP-dependent RNA helicase DDX3X OS=Homo sapiens OX=9606 GN=DDX3X PE=1 SV=3 5.96 1999.7 - 1.27E+06 - - - -0.3824 - 2.511 0.535 - 610.9 1 2 1 -0.0005 11 0 0 0 2.57E+07 2.26E+07 - - - 5.483 0.9999 221125_WJC_METTL3_EV_vs_WT_F08.09589.09589.4 0.000266 Oct-78 R.KAALEAQNALHNMK.V "sp|Q92879|CELF1_HUMAN,tr|G5EA30|G5EA30_HUMAN,tr|E9PSH0|E9PSH0_HUMAN,tr|E9PQK4|E9PQK4_HUMAN,tr|E9PKU1|E9PKU1_HUMAN" 5 1537.8035 1.25 114350 9589 4 1537.805056 385.4582 CUGBP Elav-like family member 1 OS=Homo sapiens OX=9606 GN=CELF1 PE=1 SV=2 8.6 2000 - 319723 - - - 1.0144 - 1.924 0.411 - 68.8 1 2 0 0.0016 14 0 0 0 5.62E+06 4.50E+06 - - - 3.0411 0.9985 221125_WJC_METTL3_EV_vs_WT_F08.09592.09592.2 0.0278 20-Oct K.DK[136.11]DAYSSFGSR[166.11].S "sp|O00571|DDX3X_HUMAN,sp|O15523|DDX3Y_HUMAN,tr|A0A2R8YFR4|A0A2R8YFR4_HUMAN,tr|A0A2R8YCW1|A0A2R8YCW1_HUMAN,tr|A0A2R8YDH3|A0A2R8YDH3_HUMAN,tr|A0A2R8Y645|A0A2R8Y645_HUMAN,tr|A0A2R8YF78|A0A2R8YF78_HUMAN,tr|C9J8G5|C9J8G5_HUMAN,tr|A0A2R8YCU0|A0A2R8YCU0_HUMAN,tr|A0A0D9SFB3|A0A0D9SFB3_HUMAN,tr|A0A2R8YFS5|A0A2R8YFS5_HUMAN,tr|A0A0D9SF53|A0A0D9SF53_HUMAN,tr|A0A2R8Y650|A0A2R8Y650_HUMAN,tr|A0A087WX09|A0A087WX09_HUMAN,tr|C9J081|C9J081_HUMAN,tr|A0A2R8Y5G6|A0A2R8Y5G6_HUMAN,tr|A0A0D9SG12|A0A0D9SG12_HUMAN,tr|F6S8Q4|F6S8Q4_HUMAN,tr|A0A2U3TZJ9|A0A2U3TZJ9_HUMAN,tr|A0A2R8Y4A4|A0A2R8Y4A4_HUMAN,tr|A0A2R8YF89|A0A2R8YF89_HUMAN" 21 1249.5694 1.13 114351 9592 2 1249.569226 625.792 ATP-dependent RNA helicase DDX3X OS=Homo sapiens OX=9606 GN=DDX3X PE=1 SV=3 5.96 2000.4 - 1.37E+06 - - - -0.1392 - 2.179 0.47 - 337.4 1 2 1 -0.0002 11 0 0 0 2.57E+07 2.26E+07 - - - 4.6194 0.9998 221125_WJC_METTL3_EV_vs_WT_F08.09593.09593.3 2.73E-06 15/44 K.TKQDEVNAAWQR.L "sp|Q13813|SPTN1_HUMAN,tr|A0A0D9SF54|A0A0D9SF54_HUMAN,tr|A0A0D9SGF6|A0A0D9SGF6_HUMAN" 3 1444.7059 1.07 114352 9593 3 1444.707766 482.5759 "Spectrin alpha chain, non-erythrocytic 1 OS=Homo sapiens OX=9606 GN=SPTAN1 PE=1 SV=3" 5.74 2000.5 - 1.31E+06 - - - 1.2978 - 2.482 0.497 - 304.1 1 2 1 0.0019 12 0 0 0 2.08E+07 1.95E+07 - - - 6.6003 0.9999 221125_WJC_METTL3_EV_vs_WT_F08.09594.09594.2 0.000247 15/28 K.QGGGGGGGSVPGIER.M "sp|P52272|HNRPM_HUMAN,tr|M0R019|M0R019_HUMAN,tr|A0A087X0X3|A0A087X0X3_HUMAN,tr|M0R2T0|M0R2T0_HUMAN" 4 1283.6218 1.82 114353 9594 2 1283.620851 642.8182 Heterogeneous nuclear ribonucleoprotein M OS=Homo sapiens OX=9606 GN=HNRNPM PE=1 SV=3 6 2000.6 - 680138 - - - -0.7603 - 2.824 0.478 - 527.2 1 2 0 -0.001 15 0 0 0 2.29E+07 1.25E+07 - - - 5.1236 1 221125_WJC_METTL3_EV_vs_WT_F08.09595.09595.3 2.29E-05 13/52 R.QDHAQQLATAAEER[166.11].E "sp|Q14980|NUMA1_HUMAN,tr|A0A087WY61|A0A087WY61_HUMAN,tr|F5H4J1|F5H4J1_HUMAN,tr|F5H6Y5|F5H6Y5_HUMAN" 4 1576.7469 1.23 114354 9595 3 1576.748049 526.5896 Nuclear mitotic apparatus protein 1 OS=Homo sapiens OX=9606 GN=NUMA1 PE=1 SV=2 4.65 2000.8 - 226304 - - - 0.7179 - 2.486 0.485 - 318.5 1 2 0 0.0011 14 0 0 0 1.42E+07 1.16E+07 - - - 6.3671 0.9322 221125_WJC_METTL3_EV_vs_WT_F08.09596.09596.2 2.24E-06 24-Oct F.GGGC[160.03]HVTAAVSSR[166.11].R "sp|Q9NRA8|4ET_HUMAN,tr|B1AKL5|B1AKL5_HUMAN,tr|B1AKL4|B1AKL4_HUMAN" 3 1267.5967 2.58 114355 9596 2 1267.601902 634.8056 Eukaryotic translation initiation factor 4E transporter OS=Homo sapiens OX=9606 GN=EIF4ENIF1 PE=1 SV=2 8.26 2000.9 - 142014 - - - 4.1133 - 2.087 0.541 - 334.8 1 1 0 0.0052 13 0 0 0 2.62E+06 1.02E+06 - - - 4.9235 1 221125_WJC_METTL3_EV_vs_WT_F08.09599.09599.3 1.58E-05 15/44 K.RPHVFESNPSIR.K "sp|Q16656|NRF1_HUMAN,tr|C9JP85|C9JP85_HUMAN" 2 1437.7477 1.67 114356 9599 3 1437.748851 480.2565 Nuclear respiratory factor 1 OS=Homo sapiens OX=9606 GN=NRF1 PE=1 SV=1 9.61 2001.3 - 805109 - - - 0.8033 - 3.241 0.535 - 412.4 1 2 0 0.0012 12 0 0 0 2.55E+07 1.52E+07 - - - 7.7638 1 221125_WJC_METTL3_EV_vs_WT_F08.09600.09600.3 2.81E-07 20/48 K.K[136.11]DLHDANTDLIGR[166.11].H "sp|P53985|MOT1_HUMAN,tr|Q5T8R3|Q5T8R3_HUMAN,tr|Q5T8R5|Q5T8R5_HUMAN" 3 1484.7702 1.34 114357 9600 3 1484.768274 495.9307 Monocarboxylate transporter 1 OS=Homo sapiens OX=9606 GN=SLC16A1 PE=1 SV=3 5.3 2001.4 - 677985 - - - -1.314 - 3.234 0.538 - 883.1 1 2 0 -0.002 13 0 0 0 1.47E+07 1.10E+07 - - - 7.7199 0.9998 221125_WJC_METTL3_EV_vs_WT_F08.09602.09602.3 0.000597 Dec-36 R.NGVMPSHFSR[166.11].G "sp|P39019|RS19_HUMAN,tr|A0A075B6E2|A0A075B6E2_HUMAN" 2 1140.5374 0.001 114359 9602 3 1140.537179 381.1864 40S ribosomal protein S19 OS=Homo sapiens OX=9606 GN=RPS19 PE=1 SV=2 9.76 2001.6 - 312587 - - - -0.178 - 2.25 0.312 - 351.5 1 2 0 -0.0002 10 0 0 0 0.00E+00 7.52E+06 - - - 4.3867 1 221125_WJC_METTL3_EV_vs_WT_F08.09607.09607.3 5.35E-07 18/52 R.K[136.11]AALEAQNALHNMK[136.11].V "sp|Q92879|CELF1_HUMAN,tr|G5EA30|G5EA30_HUMAN,tr|E9PSH0|E9PSH0_HUMAN,tr|E9PQK4|E9PQK4_HUMAN,tr|E9PKU1|E9PKU1_HUMAN" 5 1553.8319 2.66 114362 9607 3 1553.833391 518.9512 CUGBP Elav-like family member 1 OS=Homo sapiens OX=9606 GN=CELF1 PE=1 SV=2 8.6 2002.3 - 898412 - - - 0.9621 - 3.025 0.583 - 382.7 1 2 0 0.0015 14 0 0 0 5.14E+07 1.93E+07 - - - 7.9811 0.999 221125_WJC_METTL3_EV_vs_WT_F08.09609.09609.2 0.00473 22-Sep K.R[166.11]YELPAPSSGQK[136.11].N sp|O75934|SPF27_HUMAN 1 1349.7058 1.9 114364 9609 2 1349.705955 675.8602 Pre-mRNA-splicing factor SPF27 OS=Homo sapiens OX=9606 GN=BCAS2 PE=1 SV=1 8.59 2002.5 - 267613 - - - 0.0896 - 1.612 0.279 - 159 1 2 0 0.0001 12 0 0 0 1.54E+07 8.10E+06 - - - 2.358 1 221125_WJC_METTL3_EV_vs_WT_F08.09610.09610.2 7.72E-08 28-Sep R.SFGGGC[160.03]HVTAAVSSR[166.11].R "sp|Q9NRA8|4ET_HUMAN,tr|B1AKL5|B1AKL5_HUMAN,tr|B1AKL4|B1AKL4_HUMAN" 3 1501.6971 3.32 114365 9610 2 1501.696494 751.8558 Eukaryotic translation initiation factor 4E transporter OS=Homo sapiens OX=9606 GN=EIF4ENIF1 PE=1 SV=2 7.99 2002.6 - 170735 - - - -0.4242 - 2.203 0.658 - 204.2 1 2 0 -0.0006 15 0 0 0 8.20E+06 2.47E+06 - - - 5.8426 1 221125_WJC_METTL3_EV_vs_WT_F08.09614.09614.3 8.98E-07 16/60 R.VDEEPTTLPSGEAKPR.K "sp|Q641Q2|WAC2A_HUMAN,sp|Q9Y4E1|WAC2C_HUMAN,tr|F8W7U3|F8W7U3_HUMAN,tr|J3KP36|J3KP36_HUMAN,tr|E7ESD2|E7ESD2_HUMAN,tr|A0A0A0MT65|A0A0A0MT65_HUMAN,tr|A0A0A0MR88|A0A0A0MR88_HUMAN,tr|A0A096LPC5|A0A096LPC5_HUMAN" 8 1724.8581 1.04 114367 9614 3 1724.858979 575.96 WASH complex subunit 2A OS=Homo sapiens OX=9606 GN=WASHC2A PE=1 SV=3 4.41 2003.2 - 546992 - - - 0.5131 - 3.034 0.518 - 272.2 1 2 0 0.0009 16 0 0 0 1.06E+07 1.02E+07 - - - 7.1627 0.9999 221125_WJC_METTL3_EV_vs_WT_F08.09615.09615.3 8.13E-08 14/48 K.KDLHDANTDLIGR.H "sp|P53985|MOT1_HUMAN,tr|Q5T8R3|Q5T8R3_HUMAN,tr|Q5T8R5|Q5T8R5_HUMAN" 3 1466.7478 1.33 114368 9615 3 1466.75152 489.9232 Monocarboxylate transporter 1 OS=Homo sapiens OX=9606 GN=SLC16A1 PE=1 SV=3 5.3 2003.3 - 891113 - - - 2.5669 - 2.769 0.508 - 360.5 1 2 0 0.0038 13 0 0 0 1.48E+07 1.11E+07 - - - 6.9641 1 221125_WJC_METTL3_EV_vs_WT_F08.09618.09618.3 1.14E-08 17/60 R.VDEEPTTLPSGEAK[136.11]PR[166.11].K "sp|Q641Q2|WAC2A_HUMAN,sp|Q9Y4E1|WAC2C_HUMAN,tr|F8W7U3|F8W7U3_HUMAN,tr|J3KP36|J3KP36_HUMAN,tr|E7ESD2|E7ESD2_HUMAN,tr|A0A0A0MT65|A0A0A0MT65_HUMAN,tr|A0A0A0MR88|A0A0A0MR88_HUMAN,tr|A0A096LPC5|A0A096LPC5_HUMAN" 8 1742.8806 0.93 114371 9618 3 1742.882752 581.9675 WASH complex subunit 2A OS=Homo sapiens OX=9606 GN=WASHC2A PE=1 SV=3 4.41 2003.7 - 351286 - - - 1.2554 - 3.188 0.528 - 305.8 1 2 0 0.0022 16 0 0 0 1.09E+07 1.17E+07 - - - 7.4009 0.9698 221125_WJC_METTL3_EV_vs_WT_F08.09619.09619.4 0.122 Sep-72 R.ALQHYQNHLNIAR[166.11].E "sp|Q96AY4|TTC28_HUMAN,tr|A0A087WW06|A0A087WW06_HUMAN" 2 1586.8305 0.71 114372 9619 4 1586.834818 397.7149 Tetratricopeptide repeat protein 28 OS=Homo sapiens OX=9606 GN=TTC28 PE=1 SV=4 8.8 2003.8 - 263166 - - - 2.7035 - 1.402 0.201 - 38.6 1 2 0 0.0043 13 0 0 0 2.23E+06 3.16E+06 - - - 1.0996 1 221125_WJC_METTL3_EV_vs_WT_F08.09622.09622.2 4.64E-07 Dec-34 R.AGGPPQVAGAQAAC[160.03]SEDR.M "sp|Q9H3R5|CENPH_HUMAN,tr|B3KVZ3|B3KVZ3_HUMAN,tr|D6RBJ6|D6RBJ6_HUMAN" 3 1740.7849 4.77 114375 9622 2 1740.785947 871.3997 Centromere protein H OS=Homo sapiens OX=9606 GN=CENPH PE=1 SV=1 4.37 2004.2 - 148342 - - - 0.575 - 2.867 0.671 - 329.7 1 2 0 0.001 18 0 0 0 9.33E+06 1.96E+06 - - - 6.5862 0.996 221125_WJC_METTL3_EV_vs_WT_F08.09624.09624.4 0.095 Aug-72 R.ALQHYQNHLNIAR.E "sp|Q96AY4|TTC28_HUMAN,tr|A0A087WW06|A0A087WW06_HUMAN" 2 1576.8223 0.55 114376 9624 4 1576.82328 395.2128 Tetratricopeptide repeat protein 28 OS=Homo sapiens OX=9606 GN=TTC28 PE=1 SV=4 8.8 2004.4 - 150478 - - - 0.6481 - 1.56 0.243 - 40.7 1 2 0 0.001 13 0 0 0 3.02E+06 5.49E+06 - - - 1.5057 0.9989 221125_WJC_METTL3_EV_vs_WT_F08.09626.09626.3 0.00188 Aug-48 R.FDQQKNDYDQLQK.A sp|P15924|DESP_HUMAN 1 1668.7744 20.32 114377 9626 3 1668.774943 557.2654 Desmoplakin OS=Homo sapiens OX=9606 GN=DSP PE=1 SV=3 4.43 2004.6 - 2.52E+06 - - - 0.347 - 1.734 0.391 - 41.1 1 2 1 0.0006 13 0 0 0 2.93E+07 1.44E+06 - - - 4.3915 0.9935 221125_WJC_METTL3_EV_vs_WT_F08.09627.09627.3 0.0017 Dec-56 K.TQDLLNQNHSANAVR.P sp|Q9H040|SPRTN_HUMAN 1 1679.8339 1.5 114378 9627 3 1679.832399 560.9519 DNA-dependent metalloprotease SPRTN OS=Homo sapiens OX=9606 GN=SPRTN PE=1 SV=2 6.41 2004.7 - 1.12E+06 - - - -0.9203 - 2.329 0.441 - 197.6 1 1 0 -0.0015 15 0 0 0 1.59E+07 1.06E+07 - - - 5.6623 1 221125_WJC_METTL3_EV_vs_WT_F08.09628.09628.2 2.66E-11 14/32 K.AGYSQGATQYTQAQQTR[166.11].Q sp|Q96KR1|ZFR_HUMAN 1 1867.8688 1.27 114379 9628 2 1867.870302 934.9417 Zinc finger RNA-binding protein OS=Homo sapiens OX=9606 GN=ZFR PE=1 SV=2 8.63 2004.8 - 307475 - - - 0.7918 - 3.302 0.722 - 615.9 1 2 0 0.0015 17 0 0 0 5.26E+06 4.14E+06 - - - 7.31 1 221125_WJC_METTL3_EV_vs_WT_F08.09629.09629.3 2.86E-05 Oct-68 R.ETTGTGPNVYHENDTIAK[136.11].Y sp|Q4G0F5|VP26B_HUMAN 1 1953.916 0.78 114380 9629 3 1953.915324 652.3126 Vacuolar protein sorting-associated protein 26B OS=Homo sapiens OX=9606 GN=VPS26B PE=1 SV=2 4.65 2004.9 - 247211 - - - -0.3204 - 2.182 0.523 - 108.3 1 2 0 -0.0006 18 0 0 0 2.30E+06 2.93E+06 - - - 6.3136 1 221125_WJC_METTL3_EV_vs_WT_F08.09630.09630.2 5.10E-08 13/30 K.QGEDNSTAQDTEELEK.E "sp|Q86UE4|LYRIC_HUMAN,tr|E5RJU9|E5RJU9_HUMAN" 2 1792.7599 0.79 114381 9630 2 1792.761464 897.3872 Protein LYRIC OS=Homo sapiens OX=9606 GN=MTDH PE=1 SV=2 3.77 2005.1 - 206437 - - - 0.8746 - 2.886 0.675 - 697.1 1 2 0 0.0016 16 0 0 0 2.82E+06 3.55E+06 - - - 6.6318 1 221125_WJC_METTL3_EV_vs_WT_F08.09631.09631.2 3.59E-05 30-Dec K.QGEDNSTAQDTEELEK[136.11].E "sp|Q86UE4|LYRIC_HUMAN,tr|E5RJU9|E5RJU9_HUMAN" 2 1800.7741 0.78 114382 9631 2 1800.778072 901.3943 Protein LYRIC OS=Homo sapiens OX=9606 GN=MTDH PE=1 SV=2 3.77 2005.2 - 153003 - - - 2.2079 - 2.699 0.597 - 587.3 1 2 0 0.004 16 0 0 0 2.82E+06 3.63E+06 - - - 5.8902 1 221125_WJC_METTL3_EV_vs_WT_F08.09637.09637.2 5.11E-12 14/32 K.AGYSQGATQYTQAQQTR.Q sp|Q96KR1|ZFR_HUMAN 1 1857.8606 1.27 114386 9637 2 1857.863172 929.9376 Zinc finger RNA-binding protein OS=Homo sapiens OX=9606 GN=ZFR PE=1 SV=2 8.63 2006 - 273567 - - - 1.4097 - 3.558 0.703 - 738.1 1 2 0 0.0026 17 0 0 0 5.26E+06 4.14E+06 - - - 7.3529 0.9977 221125_WJC_METTL3_EV_vs_WT_F08.09638.09638.3 0.000114 13/64 K.QPPIQSTAGAVPVRNEK.G sp|P55081|MFAP1_HUMAN 1 1790.9639 1.31 114387 9638 3 1790.968247 597.9952 Microfibrillar-associated protein 1 OS=Homo sapiens OX=9606 GN=MFAP1 PE=1 SV=2 8.75 2006.1 - 261257 - - - 2.4294 - 2.326 0.35 - 97.2 1 2 1 0.0044 17 0 0 0 1.64E+07 1.25E+07 - - - 4.5735 0.9998 221125_WJC_METTL3_EV_vs_WT_F08.09639.09639.2 3.90E-05 26-Sep K.SNTEPQSPPIASPK.A "sp|P82094|TMF1_HUMAN,tr|F8WF45|F8WF45_HUMAN,tr|A0A2R8Y7M0|A0A2R8Y7M0_HUMAN" 3 1451.7256 2.96 114388 9639 2 1451.727069 726.8701 TATA element modulatory factor OS=Homo sapiens OX=9606 GN=TMF1 PE=1 SV=2 5.72 2006.2 - 191760 - - - 0.9961 - 1.896 0.581 - 223.6 1 2 0 0.0014 14 0 0 0 4.45E+06 1.50E+06 - - - 4.9372 0.9991 221125_WJC_METTL3_EV_vs_WT_F08.09643.09643.4 1.24E-06 13/78 K.LTDC[160.03]VVMRDPASKR.S "sp|P22626|ROA2_HUMAN,tr|A0A7I2YQN4|A0A7I2YQN4_HUMAN,tr|A0A7I2V4N0|A0A7I2V4N0_HUMAN,tr|A0A7I2V4N1|A0A7I2V4N1_HUMAN,tr|A0A7I2V4I6|A0A7I2V4I6_HUMAN,tr|A0A087WUI2|A0A087WUI2_HUMAN,tr|A0A7I2V4S4|A0A7I2V4S4_HUMAN,tr|A0A7I2V323|A0A7I2V323_HUMAN,tr|A0A7I2V3P1|A0A7I2V3P1_HUMAN,tr|A0A7I2V3P7|A0A7I2V3P7_HUMAN" 10 1646.8232 0.86 114390 9643 4 1646.827303 412.7131 Heterogeneous nuclear ribonucleoproteins A2\B1 OS=Homo sapiens OX=9606 GN=HNRNPA2B1 PE=1 SV=2 8.22 2006.8 - 1.45E+06 - - - 2.4635 - 2.325 0.414 - 184.6 1 2 1 0.0041 14 0 0 0 2.66E+07 3.08E+07 - - - 3.1354 0.9903 221125_WJC_METTL3_EV_vs_WT_F08.09644.09644.3 0.0629 Nov-40 R.QIHNFSHLVSK[136.11].Q "sp|Q9H089|LSG1_HUMAN,tr|H7C2X7|H7C2X7_HUMAN" 2 1316.7081 1.01 114391 9644 3 1316.71038 439.91 Large subunit GTPase 1 homolog OS=Homo sapiens OX=9606 GN=LSG1 PE=1 SV=2 8.76 2006.9 - 1.13E+06 - - - 1.7551 - 1.483 0.222 - 144.1 1 2 0 0.0023 11 0 0 0 1.25E+07 1.24E+07 - - - 2.1339 1 221125_WJC_METTL3_EV_vs_WT_F08.09647.09647.3 1.18E-05 17/44 K.R[166.11]PHVFESNPSIR[166.11].K "sp|Q16656|NRF1_HUMAN,tr|C9JP85|C9JP85_HUMAN" 2 1457.7642 1.7 114394 9647 3 1457.768419 486.9287 Nuclear respiratory factor 1 OS=Homo sapiens OX=9606 GN=NRF1 PE=1 SV=1 9.61 2007.1 - 435085 - - - 2.8695 - 3.409 0.539 - 516.8 1 2 0 0.0042 12 0 0 0 2.55E+07 1.49E+07 - - - 7.9476 0.9999 221125_WJC_METTL3_EV_vs_WT_F08.09649.09649.3 6.47E-06 16/56 K.AELQTALAHTQHAAR.Q "sp|Q08379|GOGA2_HUMAN,tr|A0A6Q8KRG2|A0A6Q8KRG2_HUMAN,tr|H0Y7B8|H0Y7B8_HUMAN,tr|B7ZC06|B7ZC06_HUMAN" 4 1616.8383 0.14 114396 9649 3 1616.843325 539.9534 Golgin subfamily A member 2 OS=Homo sapiens OX=9606 GN=GOLGA2 PE=1 SV=3 6.96 2007.4 - 320815 - - - 3.1067 - 3.07 0.459 - 417.3 1 2 0 0.005 15 0 0 0 4.63E+06 3.32E+07 - - - 6.5829 0.9139 221125_WJC_METTL3_EV_vs_WT_F08.09650.09650.4 0.00227 13/78 L.K[136.11]VVDR[166.11]DSEEAEIIR[166.11].K "sp|P09874|PARP1_HUMAN,tr|A0A7I2V3E1|A0A7I2V3E1_HUMAN" 2 1685.8943 1.49 114397 9650 4 1685.896467 422.4808 Poly [ADP-ribose] polymerase 1 OS=Homo sapiens OX=9606 GN=PARP1 PE=1 SV=4 4.51 2007.5 - 279866 - - - 1.3127 - 2.117 0.384 - 173.9 1 1 1 0.0022 14 0 0 0 1.74E+07 1.16E+07 - - - 2.8407 1 221125_WJC_METTL3_EV_vs_WT_F08.09653.09653.2 3.21E-10 14/34 R.AGGPPQVAGAQAAC[160.03]SEDR[166.11].M "sp|Q9H3R5|CENPH_HUMAN,tr|B3KVZ3|B3KVZ3_HUMAN,tr|D6RBJ6|D6RBJ6_HUMAN" 3 1750.7932 4.77 114400 9653 2 1750.798971 876.4039 Centromere protein H OS=Homo sapiens OX=9606 GN=CENPH PE=1 SV=1 4.37 2007.9 - 75012.4 - - - 3.2871 - 3.143 0.67 - 554.9 1 2 0 0.0058 18 0 0 0 9.33E+06 1.96E+06 - - - 6.8033 0.9999 221125_WJC_METTL3_EV_vs_WT_F08.09656.09656.3 3.41E-05 13/40 R.QIHNFSHLVSK.Q "sp|Q9H089|LSG1_HUMAN,tr|H7C2X7|H7C2X7_HUMAN" 2 1308.6939 1.01 114402 9656 3 1308.696193 437.2386 Large subunit GTPase 1 homolog OS=Homo sapiens OX=9606 GN=LSG1 PE=1 SV=2 8.76 2008.2 - 1.78E+06 - - - 1.7758 - 2.206 0.431 - 175.6 1 2 0 0.0023 11 0 0 0 1.25E+07 1.24E+07 - - - 5.5922 0.9998 221125_WJC_METTL3_EV_vs_WT_F08.09657.09657.4 8.18E-06 Dec-78 K.LTDC[160.03]VVMR[166.11]DPASK[136.11]R[166.11].S "sp|P22626|ROA2_HUMAN,tr|A0A7I2YQN4|A0A7I2YQN4_HUMAN,tr|A0A7I2V4N0|A0A7I2V4N0_HUMAN,tr|A0A7I2V4N1|A0A7I2V4N1_HUMAN,tr|A0A7I2V4I6|A0A7I2V4I6_HUMAN,tr|A0A087WUI2|A0A087WUI2_HUMAN,tr|A0A7I2V4S4|A0A7I2V4S4_HUMAN,tr|A0A7I2V323|A0A7I2V323_HUMAN,tr|A0A7I2V3P1|A0A7I2V3P1_HUMAN,tr|A0A7I2V3P7|A0A7I2V3P7_HUMAN" 10 1674.854 0.95 114403 9657 4 1674.857449 419.7208 Heterogeneous nuclear ribonucleoproteins A2\B1 OS=Homo sapiens OX=9606 GN=HNRNPA2B1 PE=1 SV=2 8.22 2008.2 - 1.75E+06 - - - 2.0676 - 2.523 0.53 - 192.9 1 2 1 0.0035 14 0 0 0 2.63E+07 2.77E+07 - - - 4.175 0.9999 221125_WJC_METTL3_EV_vs_WT_F08.09658.09658.4 5.05E-05 15/84 K.AELQTALAHTQHAAR.Q "sp|Q08379|GOGA2_HUMAN,tr|A0A6Q8KRG2|A0A6Q8KRG2_HUMAN,tr|H0Y7B8|H0Y7B8_HUMAN,tr|B7ZC06|B7ZC06_HUMAN" 4 1616.8383 0.24 114404 9658 4 1616.841504 405.2169 Golgin subfamily A member 2 OS=Homo sapiens OX=9606 GN=GOLGA2 PE=1 SV=3 6.96 2008.4 - 690204 - - - 1.9804 - 2.837 0.446 - 232.5 1 2 0 0.0032 15 0 0 0 5.98E+06 2.48E+07 - - - 3.4802 1 221125_WJC_METTL3_EV_vs_WT_F08.09661.09661.3 2.20E-08 18/68 R.AGGPPQVAGAQAAC[160.03]SEDR.M "sp|Q9H3R5|CENPH_HUMAN,tr|B3KVZ3|B3KVZ3_HUMAN,tr|D6RBJ6|D6RBJ6_HUMAN" 3 1740.7849 0.61 114407 9661 3 1740.786571 581.2689 Centromere protein H OS=Homo sapiens OX=9606 GN=CENPH PE=1 SV=1 4.37 2008.8 - 407378 - - - 0.9335 - 3.675 0.613 - 414.6 1 2 0 0.0016 18 0 0 0 8.14E+06 1.33E+07 - - - 8.6149 0.9994 221125_WJC_METTL3_EV_vs_WT_F08.09668.09668.3 0.00183 14/52 K.SEETLDEGPPK[136.11]YTK[136.11].S sp|Q00688|FKBP3_HUMAN 1 1608.7854 0.24 114413 9668 3 1608.788217 537.2691 Peptidyl-prolyl cis-trans isomerase FKBP3 OS=Homo sapiens OX=9606 GN=FKBP3 PE=1 SV=1 4.41 2009.5 - 725731 - - - 1.7616 - 2.356 0.422 - 185.9 1 2 1 0.0028 14 0 0 0 6.48E+06 2.67E+07 - - - 5.5215 0.9999 221125_WJC_METTL3_EV_vs_WT_F08.09670.09670.3 4.76E-06 13/76 R.GDNQAGGAAAAAAAPEPPPR[166.11].S "sp|O14654|IRS4_HUMAN,tr|A0A804CF45|A0A804CF45_HUMAN" 2 1797.8633 1.25 114415 9670 3 1797.867469 600.2951 Insulin receptor substrate 4 OS=Homo sapiens OX=9606 GN=IRS4 PE=1 SV=1 4.37 2009.8 - 235008 - - - 2.2944 - 2.657 0.476 - 130.6 1 2 0 0.0041 20 0 0 0 2.34E+07 1.87E+07 - - - 6.2165 0.9994 221125_WJC_METTL3_EV_vs_WT_F08.09672.09672.2 0.00305 26-Jul K.SNTEPQSPPIASPK[136.11].A "sp|P82094|TMF1_HUMAN,tr|F8WF45|F8WF45_HUMAN,tr|A0A2R8Y7M0|A0A2R8Y7M0_HUMAN" 3 1459.7398 2.1 114417 9672 2 1459.74102 730.8772 TATA element modulatory factor OS=Homo sapiens OX=9606 GN=TMF1 PE=1 SV=2 5.72 2010 - 132757 - - - 0.82 - 1.321 0.454 - 90.7 1 2 0 0.0012 14 0 0 0 1.51E+07 7.18E+06 - - - 3.0925 0.9712 221125_WJC_METTL3_EV_vs_WT_F08.09676.09676.3 7.09E-07 15/52 L.KVVDRDSEEAEIIR.K "sp|P09874|PARP1_HUMAN,tr|A0A7I2V3E1|A0A7I2V3E1_HUMAN" 2 1657.8635 1.21 114419 9676 3 1657.86792 553.6284 Poly [ADP-ribose] polymerase 1 OS=Homo sapiens OX=9606 GN=PARP1 PE=1 SV=4 4.51 2010.6 - 2.92E+06 - - - 2.6576 - 2.651 0.53 - 311 1 1 1 0.0044 14 0 0 0 2.60E+07 2.14E+07 - - - 7.0387 0.9995 221125_WJC_METTL3_EV_vs_WT_F08.09677.09677.3 0.000156 14/64 K.QPPIQSTAGAVPVR[166.11]NEK[136.11].G sp|P55081|MFAP1_HUMAN 1 1808.9864 1.31 114420 9677 3 1808.989231 604.0027 Microfibrillar-associated protein 1 OS=Homo sapiens OX=9606 GN=MFAP1 PE=1 SV=2 8.75 2010.6 - 970329 - - - 1.5838 - 2.239 0.448 - 137.8 1 2 1 0.0029 17 0 0 0 1.64E+07 1.25E+07 - - - 5.5702 1 221125_WJC_METTL3_EV_vs_WT_F08.09678.09678.3 3.60E-10 19/52 V.KLGHPDTLNQGEFK.E sp|P06702|S10A9_HUMAN 1 1582.8104 209 114421 9678 3 1582.815448 528.6107 Protein S100-A9 OS=Homo sapiens OX=9606 GN=S100A9 PE=1 SV=1 6.75 2010.8 - 745275 - - - 3.2171 - 3.516 0.633 - 511.8 1 1 0 0.0051 14 0 0 0 5.22E+07 2.50E+05 - - - 8.9373 0.9999 221125_WJC_METTL3_EV_vs_WT_F08.09681.09681.3 6.03E-05 Nov-52 R.DTPGHGSGWAETPR.T sp|O75533|SF3B1_HUMAN 1 1466.6539 1.18 114424 9681 3 1466.658452 489.8919 Splicing factor 3B subunit 1 OS=Homo sapiens OX=9606 GN=SF3B1 PE=1 SV=3 5.32 2011.1 - 237307 - - - 3.1343 - 2.235 0.541 - 121.6 1 2 0 0.0046 14 0 0 0 1.27E+07 1.08E+07 - - - 6.7076 0.9999 221125_WJC_METTL3_EV_vs_WT_F08.09682.09682.3 4.01E-05 Nov-60 R.GC[160.03]TPLHYAATSDTDGK[136.11].C "sp|O15084|ANR28_HUMAN,tr|B4DIW9|B4DIW9_HUMAN" 2 1700.7556 1.03 114425 9682 3 1700.754377 567.9258 Serine\threonine-protein phosphatase 6 regulatory ankyrin repeat subunit A OS=Homo sapiens OX=9606 GN=ANKRD28 PE=1 SV=5 5.21 2011.2 - 217936 - - - -0.6897 - 1.956 0.48 - 137 1 2 0 -0.0012 16 0 0 0 2.61E+06 2.55E+06 - - - 5.6126 0.9776 221125_WJC_METTL3_EV_vs_WT_F08.09688.09688.3 4.59E-05 14/52 L.K[136.11]VVDR[166.11]DSEEAEIIR[166.11].K "sp|P09874|PARP1_HUMAN,tr|A0A7I2V3E1|A0A7I2V3E1_HUMAN" 2 1685.8943 11.98 114429 9688 3 1685.897962 562.972 Poly [ADP-ribose] polymerase 1 OS=Homo sapiens OX=9606 GN=PARP1 PE=1 SV=4 4.51 2011.9 - 2.54E+06 - - - 2.1994 - 2.775 0.512 - 294.3 1 1 1 0.0037 14 0 0 0 3.34E+08 2.79E+07 - - - 6.9597 0.8431 221125_WJC_METTL3_EV_vs_WT_F08.09689.09689.4 0.00134 13/78 V.KLGHPDTLNQGEFK.E sp|P06702|S10A9_HUMAN 1 1582.8104 140.68 114430 9689 4 1582.813731 396.7099 Protein S100-A9 OS=Homo sapiens OX=9606 GN=S100A9 PE=1 SV=1 6.75 2012 - 662500 - - - 2.1323 - 2.3 0.295 - 149.1 1 1 0 0.0034 14 0 0 0 1.58E+07 1.12E+05 - - - 2.0959 0.9998 221125_WJC_METTL3_EV_vs_WT_F08.09691.09691.3 8.77E-05 13/48 R.R[166.11]VAEELALEQAK[136.11]K[136.11].E "sp|Q9NX63|MIC19_HUMAN,tr|A0A286YEX5|A0A286YEX5_HUMAN,tr|F8WAR4|F8WAR4_HUMAN,tr|C9JRZ6|C9JRZ6_HUMAN" 4 1509.8725 1.34 114432 9691 3 1509.877643 504.2981 MICOS complex subunit MIC19 OS=Homo sapiens OX=9606 GN=CHCHD3 PE=1 SV=1 6.23 2012.3 - 187064 - - - 3.3983 - 2.457 0.472 - 264.9 1 2 0 0.0051 13 0 0 0 5.87E+06 4.36E+06 - - - 6.2382 0.9993 221125_WJC_METTL3_EV_vs_WT_F08.09692.09692.2 0.00316 30-Aug K.SSTTTTPVQSGANVVK[136.11].L "sp|Q02086|SP2_HUMAN,tr|Q9BRW5|Q9BRW5_HUMAN" 2 1583.8246 0.8 114433 9692 2 1583.825062 792.9196 Transcription factor Sp2 OS=Homo sapiens OX=9606 GN=SP2 PE=1 SV=3 8.47 2012.4 - 145833 - - - 0.2822 - 1.542 0.351 - 114.8 1 2 0 0.0004 16 0 0 0 4.83E+06 6.01E+06 - - - 2.6981 1 221125_WJC_METTL3_EV_vs_WT_F08.09693.09693.2 5.63E-09 Oct-38 R.GDNQAGGAAAAAAAPEPPPR.S "sp|O14654|IRS4_HUMAN,tr|A0A804CF45|A0A804CF45_HUMAN" 2 1787.8551 1.44 114434 9693 2 1787.863381 894.9348 Insulin receptor substrate 4 OS=Homo sapiens OX=9606 GN=IRS4 PE=1 SV=1 4.37 2012.5 - 98380.7 - - - 4.6463 - 2.341 0.631 - 187.7 1 2 0 0.0083 20 0 0 0 6.42E+06 4.46E+06 - - - 5.7901 0.9999 221125_WJC_METTL3_EV_vs_WT_F08.09699.09699.3 0.00496 15/48 R.RVAEELALEQAKK.E "sp|Q9NX63|MIC19_HUMAN,tr|A0A286YEX5|A0A286YEX5_HUMAN,tr|F8WAR4|F8WAR4_HUMAN,tr|C9JRZ6|C9JRZ6_HUMAN" 4 1483.8358 1.49 114438 9699 3 1483.837875 495.6192 MICOS complex subunit MIC19 OS=Homo sapiens OX=9606 GN=CHCHD3 PE=1 SV=1 6.23 2013.3 - 582386 - - - 1.3701 - 2.595 0.429 - 371.3 1 2 0 0.002 13 0 0 0 5.87E+06 3.95E+06 - - - 5.9078 0.9998 221125_WJC_METTL3_EV_vs_WT_F08.09701.09701.3 0.000353 Oct-52 R.DTPGHGSGWAETPR[166.11].T sp|O75533|SF3B1_HUMAN 1 1476.6621 1.18 114440 9701 3 1476.666636 493.228 Splicing factor 3B subunit 1 OS=Homo sapiens OX=9606 GN=SF3B1 PE=1 SV=3 5.32 2013.5 - 497019 - - - 3.0549 - 2.332 0.455 - 107.4 1 2 0 0.0045 14 0 0 0 1.27E+07 1.08E+07 - - - 5.8618 0.9998 221125_WJC_METTL3_EV_vs_WT_F08.09703.09703.4 5.55E-07 13/72 K.TVFAEHISDEC[160.03]K[136.11]R[166.11].R "sp|P39023|RL3_HUMAN,tr|G5E9G0|G5E9G0_HUMAN,tr|H7C3M2|H7C3M2_HUMAN,tr|F8WCR1|F8WCR1_HUMAN,tr|B5MCW2|B5MCW2_HUMAN,tr|H7C422|H7C422_HUMAN" 6 1608.7685 0.82 114442 9703 4 1608.773932 403.1994 60S ribosomal protein L3 OS=Homo sapiens OX=9606 GN=RPL3 PE=1 SV=2 5.41 2013.8 - 261887 - - - 3.3697 - 2.417 0.485 - 104 1 2 0 0.0054 13 0 0 0 1.22E+07 1.48E+07 - - - 3.7732 0.9986 221125_WJC_METTL3_EV_vs_WT_F08.09704.09704.2 0.000976 30-Jul K.SSTTTTPVQSGANVVK.L "sp|Q02086|SP2_HUMAN,tr|Q9BRW5|Q9BRW5_HUMAN" 2 1575.8104 0.8 114443 9704 2 1575.815663 788.9125 Transcription factor Sp2 OS=Homo sapiens OX=9606 GN=SP2 PE=1 SV=3 8.47 2013.9 - 198003 - - - 3.3303 - 1.634 0.489 - 61.4 1 2 0 0.0052 16 0 0 0 4.83E+06 6.01E+06 - - - 3.8583 0.9583 221125_WJC_METTL3_EV_vs_WT_F08.09705.09705.3 0.00189 Jul-44 R.KYTELQLEAAKR.G "sp|Q5T8P6|RBM26_HUMAN,tr|E2PSN0|E2PSN0_HUMAN,tr|A0A087X0H9|A0A087X0H9_HUMAN" 3 1448.7987 1.72 114444 9705 3 1448.807216 483.9402 RNA-binding protein 26 OS=Homo sapiens OX=9606 GN=RBM26 PE=1 SV=3 8.5 2014 - 182354 - - - 5.8586 - 1.838 0.253 - 73.6 1 2 0 0.0085 12 0 0 0 2.50E+06 1.45E+06 - - - 3.0455 1 221125_WJC_METTL3_EV_vs_WT_F08.09709.09709.2 4.22E-10 Oct-38 R.GDNQAGGAAAAAAAPEPPPR[166.11].S "sp|O14654|IRS4_HUMAN,tr|A0A804CF45|A0A804CF45_HUMAN" 2 1797.8633 1.44 114448 9709 2 1797.867092 899.9389 Insulin receptor substrate 4 OS=Homo sapiens OX=9606 GN=IRS4 PE=1 SV=1 4.37 2014.6 - 63044.3 - - - 2.0847 - 2.521 0.713 - 207.1 1 2 0 0.0037 20 0 0 0 6.42E+06 4.46E+06 - - - 6.5793 0.9999 221125_WJC_METTL3_EV_vs_WT_F08.09712.09712.3 4.99E-06 15/36 K.EHFAQFGHVR.R "sp|Q9GZT3|SLIRP_HUMAN,tr|H0YJW7|H0YJW7_HUMAN,tr|A0A087WUN7|A0A087WUN7_HUMAN,tr|G3V2S9|G3V2S9_HUMAN,tr|H0YJU7|H0YJU7_HUMAN,tr|H0YJ07|H0YJ07_HUMAN,tr|H0YJ40|H0YJ40_HUMAN,tr|G3V4X6|G3V4X6_HUMAN" 8 1226.5945 1.21 114449 9712 3 1226.598641 409.8721 "SRA stem-loop-interacting RNA-binding protein, mitochondrial OS=Homo sapiens OX=9606 GN=SLIRP PE=1 SV=1" 7.02 2015 - 6.83E+06 - - - 3.3842 - 2.38 0.553 - 393.4 1 2 0 0.0042 10 0 0 0 1.16E+08 9.64E+07 - - - 7.2366 0.9997 221125_WJC_METTL3_EV_vs_WT_F08.09713.09713.3 2.88E-05 13/44 K.RYELPAPSSGQK.N sp|O75934|SPF27_HUMAN 1 1331.6834 1.61 114450 9713 3 1331.687733 444.9017 Pre-mRNA-splicing factor SPF27 OS=Homo sapiens OX=9606 GN=BCAS2 PE=1 SV=1 8.59 2015.1 - 2.24E+06 - - - 3.2808 - 2.208 0.44 - 269.3 1 2 0 0.0044 12 0 0 0 3.20E+07 1.98E+07 - - - 5.6399 0.9998 221125_WJC_METTL3_EV_vs_WT_F08.09716.09716.3 2.07E-06 13/48 K.TVFAEHISDEC[160.03]KR.R "sp|P39023|RL3_HUMAN,tr|G5E9G0|G5E9G0_HUMAN,tr|H7C3M2|H7C3M2_HUMAN,tr|F8WCR1|F8WCR1_HUMAN,tr|B5MCW2|B5MCW2_HUMAN,tr|H7C422|H7C422_HUMAN" 6 1590.746 0.92 114453 9716 3 1590.751716 531.256 60S ribosomal protein L3 OS=Homo sapiens OX=9606 GN=RPL3 PE=1 SV=2 5.41 2015.3 - 689580 - - - 3.5675 - 2.401 0.491 - 195.3 1 2 0 0.0057 13 0 0 0 1.36E+07 1.48E+07 - - - 6.3874 0.9999 221125_WJC_METTL3_EV_vs_WT_F08.09718.09718.4 5.91E-08 21/72 K.TVFAEHISDEC[160.03]KR.R "sp|P39023|RL3_HUMAN,tr|G5E9G0|G5E9G0_HUMAN,tr|H7C3M2|H7C3M2_HUMAN,tr|F8WCR1|F8WCR1_HUMAN,tr|B5MCW2|B5MCW2_HUMAN,tr|H7C422|H7C422_HUMAN" 6 1590.746 0.82 114455 9718 4 1590.751823 398.6938 60S ribosomal protein L3 OS=Homo sapiens OX=9606 GN=RPL3 PE=1 SV=2 5.41 2015.6 - 649020 - - - 3.6348 - 3.28 0.568 - 320.4 1 2 0 0.0058 13 0 0 0 1.22E+07 1.48E+07 - - - 4.6087 0.9995 221125_WJC_METTL3_EV_vs_WT_F08.09721.09721.3 2.42E-06 17/64 R.QDPPSVVVTSHQAPGEK.K sp|P25311|ZA2G_HUMAN 1 1774.885 552.22 114458 9721 3 1774.894669 592.6356 Zinc-alpha-2-glycoprotein OS=Homo sapiens OX=9606 GN=AZGP1 PE=1 SV=2 5.32 2015.9 - 275160 - - - 5.4606 - 3.266 0.482 - 379.4 1 2 0 0.0097 17 0 0 0 3.34E+08 6.04E+05 - - - 6.9012 1 221125_WJC_METTL3_EV_vs_WT_F08.09723.09723.3 5.25E-07 14/52 K.GETVNDC[160.03]HAEIISR.R "sp|P55265|DSRAD_HUMAN,tr|A0A3B3IRQ9|A0A3B3IRQ9_HUMAN,tr|A0A3B3ISU1|A0A3B3ISU1_HUMAN,tr|A0A7P0Z4K3|A0A7P0Z4K3_HUMAN,tr|A0A7P0Z4F9|A0A7P0Z4F9_HUMAN" 5 1599.7311 57.29 114460 9723 3 1599.733704 534.251 Double-stranded RNA-specific adenosine deaminase OS=Homo sapiens OX=9606 GN=ADAR PE=1 SV=4 4.65 2016.2 - 273707 - - - 1.6159 - 2.73 0.568 - 311.7 1 2 0 0.0026 14 0 0 0 2.94E+06 5.13E+04 - - - 7.5409 1 221125_WJC_METTL3_EV_vs_WT_F08.09730.09730.3 8.63E-10 17/76 R.GDNQAGGAAAAAAAPEPPPR.S "sp|O14654|IRS4_HUMAN,tr|A0A804CF45|A0A804CF45_HUMAN" 2 1787.8551 1.25 114465 9730 3 1787.859956 596.959 Insulin receptor substrate 4 OS=Homo sapiens OX=9606 GN=IRS4 PE=1 SV=1 4.37 2017.1 - 766259 - - - 2.7306 - 3.304 0.615 - 207.1 1 2 0 0.0049 20 0 0 0 2.34E+07 1.87E+07 - - - 8.2947 0.9261 221125_WJC_METTL3_EV_vs_WT_F08.09735.09735.4 0.69 Nov-90 R.SFGTEDR[166.11]PTDR[166.11]PIPPR[166.11].D "sp|Q8ND56|LS14A_HUMAN,tr|I3L4Q1|I3L4Q1_HUMAN,tr|A0A140TA76|A0A140TA76_HUMAN,tr|K7EMZ9|K7EMZ9_HUMAN" 4 1869.9476 1.01 114469 9735 4 1869.95343 468.4942 Protein LSM14 homolog A OS=Homo sapiens OX=9606 GN=LSM14A PE=1 SV=3 5.84 2017.7 - 2.25E+06 - - - 3.1338 - 1.157 0.185 - 73 1 2 0 0.0059 16 0 0 0 2.38E+08 2.35E+08 - - - 0.886 0.9967 221125_WJC_METTL3_EV_vs_WT_F08.09736.09736.3 0.0766 Nov-60 R.SFGTEDRPTDRPIPPR.D "sp|Q8ND56|LS14A_HUMAN,tr|I3L4Q1|I3L4Q1_HUMAN,tr|A0A140TA76|A0A140TA76_HUMAN,tr|K7EMZ9|K7EMZ9_HUMAN" 4 1839.9228 1.12 114470 9736 3 1839.925879 614.3149 Protein LSM14 homolog A OS=Homo sapiens OX=9606 GN=LSM14A PE=1 SV=3 5.84 2017.8 - 1.11E+06 - - - 1.6952 - 1.391 0.307 - 63.3 1 2 0 0.0031 16 0 0 0 1.18E+08 1.06E+08 - - - 2.8087 0.9999 221125_WJC_METTL3_EV_vs_WT_F08.09738.09738.3 0.0467 16/60 K.GTVRPANDFNPDADAK.A "sp|P08133|ANXA6_HUMAN,tr|E5RK69|E5RK69_HUMAN" 2 1686.7962 0.89 114472 9738 3 1686.798827 563.2727 Annexin A6 OS=Homo sapiens OX=9606 GN=ANXA6 PE=1 SV=3 4.43 2018 - 319706 - - - 1.5799 - 2.46 0.472 - 294.8 1 2 0 0.0027 16 0 0 0 4.21E+06 4.72E+06 - - - 6.1113 0.9996 221125_WJC_METTL3_EV_vs_WT_F08.09739.09739.3 0.0132 Sep-64 K.AISSASSPQSPGDALRR.V sp|Q96KR1|ZFR_HUMAN 1 1698.8649 0.65 114473 9739 3 1698.865401 567.2956 Zinc finger RNA-binding protein OS=Homo sapiens OX=9606 GN=ZFR PE=1 SV=2 9.64 2018.2 - 314048 - - - 0.2884 - 2.009 0.335 - 78.3 1 2 0 0.0005 17 0 0 0 2.03E+06 3.13E+06 - - - 4.0372 1 221125_WJC_METTL3_EV_vs_WT_F08.09741.09741.2 7.21E-11 Nov-32 M.SQGAVANANSTPPPYER.T sp|Q96PK6|RBM14_HUMAN 1 1757.8333 2 114475 9741 2 1757.842921 879.9239 RNA-binding protein 14 OS=Homo sapiens OX=9606 GN=RBM14 PE=1 SV=2 5.72 2018.4 - 130624 - - - 5.4869 - 2.765 0.685 - 281.8 1 1 0 0.0096 17 0 0 0 4.45E+06 2.23E+06 - - - 6.5978 0.7841 221125_WJC_METTL3_EV_vs_WT_F08.09742.09742.3 0.172 Aug-64 M.SQGAVANANSTPPPYER.T sp|Q96PK6|RBM14_HUMAN 1 1757.8333 1.56 114476 9742 3 1757.833265 586.9517 RNA-binding protein 14 OS=Homo sapiens OX=9606 GN=RBM14 PE=1 SV=2 5.72 2018.6 - 124489 - - - -0.0063 - 1.838 0.231 - 73.6 1 1 0 0 17 0 0 0 4.29E+06 2.76E+06 - - - 2.6531 0.9774 221125_WJC_METTL3_EV_vs_WT_F08.09743.09743.3 0.00691 Jul-68 R.TEC[160.03]AEPPR[166.11]DEPPADGALK[136.11].R "sp|P53041|PPP5_HUMAN,tr|H0YDU8|H0YDU8_HUMAN" 2 1969.917 0.36 114477 9743 3 1969.922336 657.6463 Serine\threonine-protein phosphatase 5 OS=Homo sapiens OX=9606 GN=PPP5C PE=1 SV=1 4.18 2018.7 - 89290.9 - - - 2.6955 - 1.222 0.353 - 52.5 1 2 1 0.0053 18 0 0 0 3.79E+05 1.05E+06 - - - 2.9734 1 221125_WJC_METTL3_EV_vs_WT_F08.09744.09744.2 6.50E-08 Dec-32 M.SQGAVANANSTPPPYER[166.11].T sp|Q96PK6|RBM14_HUMAN 1 1767.8415 2.35 114478 9744 2 1767.848113 884.928 RNA-binding protein 14 OS=Homo sapiens OX=9606 GN=RBM14 PE=1 SV=2 5.72 2018.8 - 67663.1 - - - 3.7147 - 2.688 0.68 - 328 1 1 0 0.0066 17 0 0 0 6.02E+06 2.56E+06 - - - 6.4924 0.9993 221125_WJC_METTL3_EV_vs_WT_F08.09746.09746.4 0.000245 14/90 R.SFGTEDRPTDRPIPPR.D "sp|Q8ND56|LS14A_HUMAN,tr|I3L4Q1|I3L4Q1_HUMAN,tr|A0A140TA76|A0A140TA76_HUMAN,tr|K7EMZ9|K7EMZ9_HUMAN" 4 1839.9228 1.01 114479 9746 4 1839.928421 460.988 Protein LSM14 homolog A OS=Homo sapiens OX=9606 GN=LSM14A PE=1 SV=3 5.84 2019.1 - 2.56E+06 - - - 3.0768 - 1.922 0.385 - 117.6 1 2 0 0.0057 16 0 0 0 2.38E+08 2.35E+08 - - - 2.8056 0.9477 221125_WJC_METTL3_EV_vs_WT_F08.09749.09749.3 0.00125 Nov-56 F.SQPPAPPHQNTFPPR.S sp|Q96I24|FUBP3_HUMAN 1 1669.8325 0.42 114481 9749 3 1669.836906 557.6181 Far upstream element-binding protein 3 OS=Homo sapiens OX=9606 GN=FUBP3 PE=1 SV=2 9.49 2019.5 - 252360 - - - 2.6458 - 2.338 0.352 - 137.6 1 1 0 0.0044 15 0 0 0 5.49E+06 1.32E+07 - - - 4.6794 0.994 221125_WJC_METTL3_EV_vs_WT_F08.09759.09759.3 0.0437 Dec-48 K.IQDKEGIPPDQQR.L "sp|P62979|RS27A_HUMAN,sp|P0CG48|UBC_HUMAN,sp|P0CG48|UBC_HUMAN,sp|P0CG48|UBC_HUMAN,sp|P0CG48|UBC_HUMAN,sp|P0CG48|UBC_HUMAN,sp|P0CG48|UBC_HUMAN,sp|P0CG48|UBC_HUMAN,sp|P0CG48|UBC_HUMAN,sp|P0CG48|UBC_HUMAN,sp|P0CG47|UBB_HUMAN,sp|P0CG47|UBB_HUMAN,sp|P0CG47|UBB_HUMAN,sp|P62987|RL40_HUMAN,tr|F5H388|F5H388_HUMAN,tr|F5H388|F5H388_HUMAN,tr|F5GYU3|F5GYU3_HUMAN,tr|F5GYU3|F5GYU3_HUMAN,tr|B4DV12|B4DV12_HUMAN,tr|B4DV12|B4DV12_HUMAN,tr|J3QSA3|J3QSA3_HUMAN,tr|Q5PY61|Q5PY61_HUMAN,tr|Q5PY61|Q5PY61_HUMAN,tr|Q5PY61|Q5PY61_HUMAN,tr|F5H2Z3|F5H2Z3_HUMAN,tr|F5H2Z3|F5H2Z3_HUMAN,tr|M0R2S1|M0R2S1_HUMAN,tr|J3QS39|J3QS39_HUMAN,tr|J3QTR3|J3QTR3_HUMAN,tr|Q96C32|Q96C32_HUMAN,tr|Q96C32|Q96C32_HUMAN,tr|Q96C32|Q96C32_HUMAN,tr|Q96C32|Q96C32_HUMAN,tr|M0R1V7|M0R1V7_HUMAN,tr|F5H747|F5H747_HUMAN,tr|F5H747|F5H747_HUMAN,tr|F5GXK7|F5GXK7_HUMAN,tr|F5GXK7|F5GXK7_HUMAN,tr|M0R1M6|M0R1M6_HUMAN,tr|F5H6Q2|F5H6Q2_HUMAN,tr|F5H6Q2|F5H6Q2_HUMAN,tr|F5GZ39|F5GZ39_HUMAN,tr|J3QKN0|J3QKN0_HUMAN,tr|J3QKN0|J3QKN0_HUMAN,tr|F5H265|F5H265_HUMAN,tr|F5H265|F5H265_HUMAN,tr|A0A2R8Y422|A0A2R8Y422_HUMAN" 47 1522.774 0.75 114490 9759 3 1522.778846 508.5986 Ubiquitin-40S ribosomal protein S27a OS=Homo sapiens OX=9606 GN=RPS27A PE=1 SV=2 4.56 2020.7 - 961577 - - - 3.2021 - 2.027 0.34 - 234.5 1 2 1 0.0049 13 0 0 0 1.40E+07 1.85E+07 - - - 4.245 0.9999 221125_WJC_METTL3_EV_vs_WT_F08.09762.09762.4 2.24E-06 16/78 R.WPTGDNIHAEHQVR.S "sp|Q14671|PUM1_HUMAN,tr|Q5T1Z8|Q5T1Z8_HUMAN,tr|H0YEH2|H0YEH2_HUMAN,tr|Q5T1Z4|Q5T1Z4_HUMAN,tr|E9PR38|E9PR38_HUMAN" 5 1658.7914 2.32 114492 9762 4 1658.79586 415.7051 Pumilio homolog 1 OS=Homo sapiens OX=9606 GN=PUM1 PE=1 SV=3 5.99 2021.1 - 435537 - - - 2.7176 - 2.743 0.517 - 199.1 1 2 0 0.0045 14 0 0 0 1.07E+08 4.61E+07 - - - 4.092 0.9892 221125_WJC_METTL3_EV_vs_WT_F08.09764.09764.3 0.165 Dec-36 R.R[166.11]LAELSDYR[166.11]R[166.11].L sp|Q96PK6|RBM14_HUMAN 1 1307.7088 1.98 114494 9764 3 1307.715046 436.9102 RNA-binding protein 14 OS=Homo sapiens OX=9606 GN=RBM14 PE=1 SV=2 8.74 2021.3 - 384689 - - - 4.7434 - 1.94 0.27 - 140 1 2 0 0.0062 10 0 0 0 7.55E+06 3.81E+06 - - - 3.4839 0.9998 221125_WJC_METTL3_EV_vs_WT_F08.09766.09766.3 6.59E-08 16/52 R.WPTGDNIHAEHQVR.S "sp|Q14671|PUM1_HUMAN,tr|Q5T1Z8|Q5T1Z8_HUMAN,tr|H0YEH2|H0YEH2_HUMAN,tr|Q5T1Z4|Q5T1Z4_HUMAN,tr|E9PR38|E9PR38_HUMAN" 5 1658.7914 2.2 114496 9766 3 1658.799458 553.9377 Pumilio homolog 1 OS=Homo sapiens OX=9606 GN=PUM1 PE=1 SV=3 5.99 2021.6 - 310369 - - - 4.8867 - 3.068 0.567 - 322.2 1 2 0 0.0081 14 0 0 0 7.14E+07 3.24E+07 - - - 7.8384 0.9998 221125_WJC_METTL3_EV_vs_WT_F08.09767.09767.3 5.93E-05 Dec-64 R.LEKPETQSSPITVQSSK.D "sp|Q96CB8|INT12_HUMAN,tr|A0A087WXN4|A0A087WXN4_HUMAN,tr|E9PGI3|E9PGI3_HUMAN" 3 1857.9684 4.75 114497 9767 3 1857.973622 620.3301 Integrator complex subunit 12 OS=Homo sapiens OX=9606 GN=INTS12 PE=1 SV=1 6.14 2021.7 - 307796 - - - 2.8251 - 2.361 0.453 - 179.4 1 2 0 0.0052 17 0 0 0 1.24E+07 2.60E+06 - - - 5.7594 0.9502 221125_WJC_METTL3_EV_vs_WT_F08.09772.09772.2 0.00613 28-Jul Y.SQSLLQQQSAAGSQK.E "sp|O95319|CELF2_HUMAN,tr|E9PC62|E9PC62_HUMAN,tr|A0A1B0GU44|A0A1B0GU44_HUMAN,tr|A0A0J9YX66|A0A0J9YX66_HUMAN,tr|A0A1B0GUN8|A0A1B0GUN8_HUMAN,tr|Q5VZZ6|Q5VZZ6_HUMAN,tr|A0A0J9YXJ0|A0A0J9YXJ0_HUMAN,tr|V9GYD9|V9GYD9_HUMAN" 8 1559.7903 1.56 114502 9772 2 1559.793787 780.9025 CUGBP Elav-like family member 2 OS=Homo sapiens OX=9606 GN=CELF2 PE=1 SV=1 8.47 2022.4 - 79009.7 - - - 2.2041 - 1.305 0.511 - 116.2 1 1 0 0.0034 15 0 0 0 6.84E+05 4.38E+05 - - - 3.4686 0.9998 221125_WJC_METTL3_EV_vs_WT_F08.09776.09776.4 1.37E-05 15/78 R.WPTGDNIHAEHQVR[166.11].S "sp|Q14671|PUM1_HUMAN,tr|Q5T1Z8|Q5T1Z8_HUMAN,tr|H0YEH2|H0YEH2_HUMAN,tr|Q5T1Z4|Q5T1Z4_HUMAN,tr|E9PR38|E9PR38_HUMAN" 5 1668.7996 2.32 114504 9776 4 1668.803733 418.2072 Pumilio homolog 1 OS=Homo sapiens OX=9606 GN=PUM1 PE=1 SV=3 5.99 2022.8 - 1.31E+06 - - - 2.4634 - 3.251 0.428 - 149.6 1 2 0 0.0041 14 0 0 0 1.07E+08 4.60E+07 - - - 3.3792 0.9977 221125_WJC_METTL3_EV_vs_WT_F08.09779.09779.3 0.000604 13/60 R.SFGTEDR[166.11]PTDR[166.11]PIPPR[166.11].D "sp|Q8ND56|LS14A_HUMAN,tr|I3L4Q1|I3L4Q1_HUMAN,tr|A0A140TA76|A0A140TA76_HUMAN,tr|K7EMZ9|K7EMZ9_HUMAN" 4 1869.9476 1.12 114507 9779 3 1869.953594 624.3231 Protein LSM14 homolog A OS=Homo sapiens OX=9606 GN=LSM14A PE=1 SV=3 5.84 2023.1 - 610059 - - - 3.2215 - 1.981 0.314 - 76.1 1 2 0 0.006 16 0 0 0 1.18E+08 1.06E+08 - - - 3.7932 1 221125_WJC_METTL3_EV_vs_WT_F08.09784.09784.2 1.10E-07 14/28 R.NSEEQPSGGTTVLQR[166.11].L sp|Q4VCS5|AMOT_HUMAN 1 1611.7728 1.45 114512 9784 2 1611.776089 806.8937 Angiomotin OS=Homo sapiens OX=9606 GN=AMOT PE=1 SV=1 4.53 2023.7 - 239669 - - - 2.0419 - 2.824 0.596 - 360.3 1 2 0 0.0033 15 0 0 0 8.55E+06 5.92E+06 - - - 5.9944 1 221125_WJC_METTL3_EV_vs_WT_F08.09786.09786.2 1.33E-07 14/28 R.NSEEQPSGGTTVLQR.L sp|Q4VCS5|AMOT_HUMAN 1 1601.7645 1.45 114514 9786 2 1601.768455 801.8895 Angiomotin OS=Homo sapiens OX=9606 GN=AMOT PE=1 SV=1 4.53 2024 - 196377 - - - 2.4517 - 2.847 0.635 - 426.6 1 2 0 0.0039 15 0 0 0 8.55E+06 5.92E+06 - - - 6.3022 0.9999 221125_WJC_METTL3_EV_vs_WT_F08.09791.09791.3 1.68E-05 15/48 K.VDNDENEHQLSLR.T "sp|P06748|NPM_HUMAN,tr|A0A7I2V4G8|A0A7I2V4G8_HUMAN,tr|A0A7I2YQC0|A0A7I2YQC0_HUMAN,tr|A0A7I2V433|A0A7I2V433_HUMAN,tr|A0A7I2V579|A0A7I2V579_HUMAN,tr|A0A7I2V2X9|A0A7I2V2X9_HUMAN,tr|A0A7I2V3G5|A0A7I2V3G5_HUMAN,tr|A0A7I2V5S2|A0A7I2V5S2_HUMAN,tr|A0A7I2V3U2|A0A7I2V3U2_HUMAN,tr|E5RGW4|E5RGW4_HUMAN" 10 1567.7227 0.97 114517 9791 3 1567.727801 523.5815 Nucleophosmin OS=Homo sapiens OX=9606 GN=NPM1 PE=1 SV=2 4.31 2024.7 - 1.98E+06 - - - 3.2774 - 2.993 0.545 - 469.8 1 2 0 0.0051 13 0 0 0 1.32E+08 1.36E+08 - - - 7.5871 0.9989 221125_WJC_METTL3_EV_vs_WT_F08.09796.09796.3 0.00338 Sep-52 R.LQFQQQQNSIHAAK[136.11].Q "sp|Q6PJT7|ZC3HE_HUMAN,tr|G3V3Y4|G3V3Y4_HUMAN,tr|G3V256|G3V256_HUMAN,tr|G3V5I6|G3V5I6_HUMAN,tr|A0A3B3IT62|A0A3B3IT62_HUMAN,tr|H0YJA2|H0YJA2_HUMAN" 6 1647.8573 1.63 114522 9796 3 1647.858033 550.293 Zinc finger CCCH domain-containing protein 14 OS=Homo sapiens OX=9606 GN=ZC3H14 PE=1 SV=1 8.76 2025.2 - 594679 - - - 0.4733 - 1.837 0.278 - 61.2 1 2 0 0.0008 14 0 0 0 3.27E+07 2.01E+07 - - - 3.2553 0.9999 221125_WJC_METTL3_EV_vs_WT_F08.09797.09797.3 2.25E-06 14/52 R.LQFQQQQNSIHAAK.Q "sp|Q6PJT7|ZC3HE_HUMAN,tr|G3V3Y4|G3V3Y4_HUMAN,tr|G3V256|G3V256_HUMAN,tr|G3V5I6|G3V5I6_HUMAN,tr|A0A3B3IT62|A0A3B3IT62_HUMAN,tr|H0YJA2|H0YJA2_HUMAN" 6 1639.8431 1.59 114523 9797 3 1639.847527 547.6216 Zinc finger CCCH domain-containing protein 14 OS=Homo sapiens OX=9606 GN=ZC3H14 PE=1 SV=1 8.76 2025.3 - 543259 - - - 2.7283 - 2.597 0.462 - 323.5 1 2 0 0.0045 14 0 0 0 3.18E+07 2.00E+07 - - - 6.2258 0.9984 221125_WJC_METTL3_EV_vs_WT_F08.09801.09801.3 1.81E-09 18/48 W.PTGDNIHAEHQVR.S "sp|Q14671|PUM1_HUMAN,tr|Q5T1Z8|Q5T1Z8_HUMAN,tr|H0YEH2|H0YEH2_HUMAN,tr|Q5T1Z4|Q5T1Z4_HUMAN,tr|E9PR38|E9PR38_HUMAN" 5 1472.712 0.6 114527 9801 3 1472.714343 491.9113 Pumilio homolog 1 OS=Homo sapiens OX=9606 GN=PUM1 PE=1 SV=3 6.01 2025.8 - 360104 - - - 1.5645 - 3.225 0.586 - 543.7 1 1 0 0.0023 13 0 0 0 4.61E+06 7.72E+06 - - - 8.2474 0.9987 221125_WJC_METTL3_EV_vs_WT_F08.09802.09802.3 0.000437 Oct-52 R.K[136.11]VYFHTDAAQAVGK[136.11].L "sp|Q9Y697|NFS1_HUMAN,tr|F2Z2E7|F2Z2E7_HUMAN" 2 1549.8224 0.95 114528 9802 3 1549.827517 517.6147 "Cysteine desulfurase, mitochondrial OS=Homo sapiens OX=9606 GN=NFS1 PE=1 SV=3" 8.51 2025.9 - 322262 - - - 3.3165 - 1.64 0.403 - 93.3 1 2 0 0.0051 14 0 0 0 2.24E+06 2.36E+06 - - - 4.3463 0.9944 221125_WJC_METTL3_EV_vs_WT_F08.09803.09803.2 1.00E-07 13/28 R.SDSPVPTAPTSGGPK[136.11].P "sp|Q86U44|MTA70_HUMAN,tr|B4E349|B4E349_HUMAN,tr|F5H6D8|F5H6D8_HUMAN,tr|B4DTN4|B4DTN4_HUMAN" 4 1404.6976 0.02 114529 9803 2 1404.697918 703.3561 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 5.55 2026.1 - 271613 - - - 0.2093 - 2.27 0.591 - 315.8 1 1 0 0.0003 15 0 0 0 1.86E+07 7.46E+08 - - - 5.4215 1 221125_WJC_METTL3_EV_vs_WT_F08.09808.09808.2 4.38E-10 13/30 K.AAC[160.03]SSSEEDDC[160.03]VSLSK[136.11].A "sp|Q9H019|MFR1L_HUMAN,tr|E9PLD2|E9PLD2_HUMAN,tr|E9PPF9|E9PPF9_HUMAN" 3 1751.7069 2 114534 9808 2 1751.710171 876.8607 Mitochondrial fission regulator 1-like OS=Homo sapiens OX=9606 GN=MTFR1L PE=1 SV=2 3.92 2026.7 - 80319.7 - - - 1.8416 - 2.69 0.678 - 458.5 1 2 0 0.0032 16 0 0 0 1.39E+07 6.93E+06 - - - 6.4805 0.9991 221125_WJC_METTL3_EV_vs_WT_F08.09810.09810.3 0.00396 Nov-44 R.SFRPYHTTDDLR.M "sp|Q14687|GSE1_HUMAN,tr|H0Y613|H0Y613_HUMAN,tr|C9JLW9|C9JLW9_HUMAN" 3 1506.7215 2.39 114535 9810 3 1506.725202 503.2478 Genetic suppressor element 1 OS=Homo sapiens OX=9606 GN=GSE1 PE=1 SV=3 6.46 2026.9 - 395632 - - - 2.4298 - 2.012 0.324 - 149.4 1 2 0 0.0037 12 0 0 0 4.31E+06 1.80E+06 - - - 4.0891 0.9994 221125_WJC_METTL3_EV_vs_WT_F08.09816.09816.4 0.00247 14/90 R.SFGTEDR[166.11]PTDR[166.11]PIPPR[166.11].D "sp|Q8ND56|LS14A_HUMAN,tr|I3L4Q1|I3L4Q1_HUMAN,tr|A0A140TA76|A0A140TA76_HUMAN,tr|K7EMZ9|K7EMZ9_HUMAN" 4 1869.9476 1.01 114541 9816 4 1869.950242 468.4942 Protein LSM14 homolog A OS=Homo sapiens OX=9606 GN=LSM14A PE=1 SV=3 5.84 2027.4 - 1.59E+06 - - - 1.4289 - 1.635 0.341 - 108.7 1 2 0 0.0027 16 0 0 0 2.38E+08 2.35E+08 - - - 2.3665 0.9999 221125_WJC_METTL3_EV_vs_WT_F08.09817.09817.4 5.26E-05 17/84 K.QRPAAGAPPELHSLR.T sp|Q96ED9|HOOK2_HUMAN 1 1598.8641 4.14 114542 9817 4 1598.867044 400.7233 Protein Hook homolog 2 OS=Homo sapiens OX=9606 GN=HOOK2 PE=1 SV=3 9.61 2027.6 - 433828 - - - 1.8269 - 3.435 0.453 - 295.9 1 2 0 0.0029 15 0 0 0 1.01E+07 2.43E+06 - - - 3.6096 0.9998 221125_WJC_METTL3_EV_vs_WT_F08.09820.09820.2 5.26E-06 13/26 K.QVQPQLQQEAEPQK.Q "sp|Q9ULV3|CIZ1_HUMAN,tr|Q5SYW2|Q5SYW2_HUMAN,tr|F5H2X7|F5H2X7_HUMAN,tr|H0Y5D5|H0Y5D5_HUMAN,tr|A0A494C0L7|A0A494C0L7_HUMAN,tr|Q9BTG3|Q9BTG3_HUMAN" 6 1649.8373 3.13 114545 9820 2 1649.840325 825.9259 Cip1-interacting zinc finger protein OS=Homo sapiens OX=9606 GN=CIZ1 PE=1 SV=2 4.53 2028 - 379316 - - - 1.8341 - 2.526 0.572 - 544.2 1 2 0 0.003 14 0 0 0 8.12E+07 2.59E+07 - - - 5.5902 1 221125_WJC_METTL3_EV_vs_WT_F08.09821.09821.2 1.03E-10 13/30 K.AAC[160.03]SSSEEDDC[160.03]VSLSK.A "sp|Q9H019|MFR1L_HUMAN,tr|E9PLD2|E9PLD2_HUMAN,tr|E9PPF9|E9PPF9_HUMAN" 3 1743.6927 2 114546 9821 2 1743.697092 872.8536 Mitochondrial fission regulator 1-like OS=Homo sapiens OX=9606 GN=MTFR1L PE=1 SV=2 3.92 2028.1 - 352775 - - - 2.493 - 2.883 0.759 - 434.2 1 2 0 0.0043 16 0 0 0 1.39E+07 6.93E+06 - - - 7.2488 1 221125_WJC_METTL3_EV_vs_WT_F08.09822.09822.2 6.15E-10 15/24 K.VDNDENEHQLSLR[166.11].T "sp|P06748|NPM_HUMAN,tr|A0A7I2V4G8|A0A7I2V4G8_HUMAN,tr|A0A7I2YQC0|A0A7I2YQC0_HUMAN,tr|A0A7I2V433|A0A7I2V433_HUMAN,tr|A0A7I2V579|A0A7I2V579_HUMAN,tr|A0A7I2V2X9|A0A7I2V2X9_HUMAN,tr|A0A7I2V3G5|A0A7I2V3G5_HUMAN,tr|A0A7I2V5S2|A0A7I2V5S2_HUMAN,tr|A0A7I2V3U2|A0A7I2V3U2_HUMAN,tr|E5RGW4|E5RGW4_HUMAN" 10 1577.7309 0.99 114547 9822 2 1577.733734 789.8727 Nucleophosmin OS=Homo sapiens OX=9606 GN=NPM1 PE=1 SV=2 4.31 2028.2 - 305571 - - - 1.7753 - 3.048 0.66 - 1102.4 1 2 0 0.0028 13 0 0 0 4.73E+06 4.76E+06 - - - 6.7752 1 221125_WJC_METTL3_EV_vs_WT_F08.09824.09824.2 4.12E-07 13/24 K.VDNDENEHQLSLR.T "sp|P06748|NPM_HUMAN,tr|A0A7I2V4G8|A0A7I2V4G8_HUMAN,tr|A0A7I2YQC0|A0A7I2YQC0_HUMAN,tr|A0A7I2V433|A0A7I2V433_HUMAN,tr|A0A7I2V579|A0A7I2V579_HUMAN,tr|A0A7I2V2X9|A0A7I2V2X9_HUMAN,tr|A0A7I2V3G5|A0A7I2V3G5_HUMAN,tr|A0A7I2V5S2|A0A7I2V5S2_HUMAN,tr|A0A7I2V3U2|A0A7I2V3U2_HUMAN,tr|E5RGW4|E5RGW4_HUMAN" 10 1567.7227 0.99 114549 9824 2 1567.724268 784.8686 Nucleophosmin OS=Homo sapiens OX=9606 GN=NPM1 PE=1 SV=2 4.31 2028.5 - 263562 - - - 1.0238 - 2.732 0.6 - 586.6 1 2 0 0.0016 13 0 0 0 4.73E+06 4.76E+06 - - - 6.0515 0.9657 221125_WJC_METTL3_EV_vs_WT_F08.09829.09829.2 0.000173 Jun-32 S.SSLNQQGAHSALSSAST.- tr|D6R9F3|D6R9F3_HUMAN 1 1644.7703 - 114554 9829 2 1644.772653 823.3924 Matrin-3 (Fragment) OS=Homo sapiens OX=9606 GN=MATR3 PE=1 SV=1 6.46 2029.1 - 95273.7 - - - 1.4057 - 1.583 0.432 - 68.3 1 1 0 0.0023 17 0 0 0 - - - - - 3.3603 0.9996 221125_WJC_METTL3_EV_vs_WT_F08.09832.09832.3 8.77E-08 13/48 K.HETQSLALDAC[160.03]SR.D "sp|O75410|TACC1_HUMAN,tr|E7EVI4|E7EVI4_HUMAN,tr|E5RFM9|E5RFM9_HUMAN,tr|A0A0C4DGD5|A0A0C4DGD5_HUMAN,tr|R4GMT7|R4GMT7_HUMAN,tr|H0YAY0|H0YAY0_HUMAN,tr|A0A0C4DGD3|A0A0C4DGD3_HUMAN,tr|H0YBT8|H0YBT8_HUMAN,tr|E7ET87|E7ET87_HUMAN" 9 1486.6834 1.09 114555 9832 3 1486.685424 496.5684 Transforming acidic coiled-coil-containing protein 1 OS=Homo sapiens OX=9606 GN=TACC1 PE=1 SV=2 5.32 2029.6 - 771409 - - - 1.3338 - 2.43 0.288 - 322.8 1 2 0 0.002 13 0 0 0 2.55E+07 2.34E+07 - - - 4.1577 0.996 221125_WJC_METTL3_EV_vs_WT_F08.09834.09834.3 0.0192 Sep-52 R.TSDSTPDPQR[166.11]VPLR[166.11].L "sp|P52948|NUP98_HUMAN,tr|H7C3P6|H7C3P6_HUMAN" 2 1587.812 1.27 114557 9834 3 1587.809632 530.2779 Nuclear pore complex protein Nup98-Nup96 OS=Homo sapiens OX=9606 GN=NUP98 PE=1 SV=4 5.63 2029.8 - 1.23E+06 - - - -1.475 - 1.866 0.305 - 63.6 1 2 1 -0.0023 14 0 0 0 2.77E+07 2.17E+07 - - - 3.5976 0.9946 221125_WJC_METTL3_EV_vs_WT_F08.09838.09838.4 0.002 Dec-72 R.TDFKEEPEPGFKR.L "sp|P47897|SYQ_HUMAN,tr|B4DDN1|B4DDN1_HUMAN,tr|H7C0R3|H7C0R3_HUMAN,tr|A0A0U1RQX5|A0A0U1RQX5_HUMAN,tr|A0A1B0GVU9|A0A1B0GVU9_HUMAN,tr|A0A0U1RRC8|A0A0U1RRC8_HUMAN" 6 1578.7678 0.92 114561 9838 4 1578.769317 395.6992 Glutamine--tRNA ligase OS=Homo sapiens OX=9606 GN=QARS1 PE=1 SV=1 4.87 2030.2 - 570109 - - - 0.9469 - 1.939 0.282 - 105.3 1 2 1 0.0015 13 0 0 0 7.14E+06 7.77E+06 - - - 1.9256 1 221125_WJC_METTL3_EV_vs_WT_F08.09839.09839.3 1.16E-06 19/68 R.AGAGMITQHSSNASPINR[166.11].L "sp|Q9NWH9|SLTM_HUMAN,tr|H7C3F4|H7C3F4_HUMAN,tr|H0YKH2|H0YKH2_HUMAN" 3 1820.8827 0.98 114562 9839 3 1820.884799 607.9682 SAFB-like transcription modulator OS=Homo sapiens OX=9606 GN=SLTM PE=1 SV=2 9.8 2030.3 - 565084 - - - 1.1533 - 3.955 0.572 - 538.8 1 2 0 0.0021 18 0 0 0 6.07E+06 6.19E+06 - - - 8.3405 1 221125_WJC_METTL3_EV_vs_WT_F08.09842.09842.2 3.43E-08 15/22 V.DNDENEHQLSLR[166.11].T "sp|P06748|NPM_HUMAN,tr|A0A7I2V4G8|A0A7I2V4G8_HUMAN,tr|A0A7I2YQC0|A0A7I2YQC0_HUMAN,tr|A0A7I2V433|A0A7I2V433_HUMAN,tr|A0A7I2V579|A0A7I2V579_HUMAN,tr|A0A7I2V2X9|A0A7I2V2X9_HUMAN,tr|A0A7I2V3G5|A0A7I2V3G5_HUMAN,tr|A0A7I2V5S2|A0A7I2V5S2_HUMAN,tr|A0A7I2V3U2|A0A7I2V3U2_HUMAN,tr|E5RGW4|E5RGW4_HUMAN" 10 1478.6625 0.9 114565 9842 2 1478.666906 740.3385 Nucleophosmin OS=Homo sapiens OX=9606 GN=NPM1 PE=1 SV=2 4.31 2030.7 - 183039 - - - 2.9669 - 3.247 0.664 - 1246.9 1 1 0 0.0044 12 0 0 0 1.24E+06 1.38E+06 - - - 7.0427 1 221125_WJC_METTL3_EV_vs_WT_F08.09843.09843.2 1.24E-08 16/22 V.DNDENEHQLSLR.T "sp|P06748|NPM_HUMAN,tr|A0A7I2V4G8|A0A7I2V4G8_HUMAN,tr|A0A7I2YQC0|A0A7I2YQC0_HUMAN,tr|A0A7I2V433|A0A7I2V433_HUMAN,tr|A0A7I2V579|A0A7I2V579_HUMAN,tr|A0A7I2V2X9|A0A7I2V2X9_HUMAN,tr|A0A7I2V3G5|A0A7I2V3G5_HUMAN,tr|A0A7I2V5S2|A0A7I2V5S2_HUMAN,tr|A0A7I2V3U2|A0A7I2V3U2_HUMAN,tr|E5RGW4|E5RGW4_HUMAN" 10 1468.6542 0.9 114566 9843 2 1468.6594 735.3344 Nucleophosmin OS=Homo sapiens OX=9606 GN=NPM1 PE=1 SV=2 4.31 2030.8 - 161309 - - - 3.5073 - 3.132 0.702 - 1288.7 1 1 0 0.0052 12 0 0 0 1.24E+06 1.38E+06 - - - 7.2283 1 221125_WJC_METTL3_EV_vs_WT_F08.09845.09845.2 4.55E-11 28-Nov R.SGC[160.03]DEVSSTSEIGTR[166.11].Y "sp|Q9H2Y7|ZN106_HUMAN,tr|H3BS99|H3BS99_HUMAN,tr|A0A0C4DGM5|A0A0C4DGM5_HUMAN,tr|H3BSS6|H3BSS6_HUMAN" 4 1593.6816 -1 114568 9845 2 1593.684401 797.8481 Zinc finger protein 106 OS=Homo sapiens OX=9606 GN=ZNF106 PE=1 SV=1 4.14 2031.1 - 136619 - - - 1.7576 - 2.567 0.75 - 268.6 1 2 0 0.0028 15 0 0 0 0.00E+00 0.00E+00 - - - 6.8974 1 221125_WJC_METTL3_EV_vs_WT_F08.09846.09846.2 9.53E-11 28-Dec R.SGC[160.03]DEVSSTSEIGTR.Y "sp|Q9H2Y7|ZN106_HUMAN,tr|H3BS99|H3BS99_HUMAN,tr|A0A0C4DGM5|A0A0C4DGM5_HUMAN,tr|H3BSS6|H3BSS6_HUMAN" 4 1583.6733 1.26 114569 9846 2 1583.669426 792.8439 Zinc finger protein 106 OS=Homo sapiens OX=9606 GN=ZNF106 PE=1 SV=1 4.14 2031.2 - 132468 - - - -2.4652 - 2.765 0.766 - 356.8 1 2 0 -0.0039 15 0 0 0 8.49E+05 6.76E+05 - - - 7.1979 1 221125_WJC_METTL3_EV_vs_WT_F08.09848.09848.3 3.91E-11 15/48 K.VDNDENEHQLSLR[166.11].T "sp|P06748|NPM_HUMAN,tr|A0A7I2V4G8|A0A7I2V4G8_HUMAN,tr|A0A7I2YQC0|A0A7I2YQC0_HUMAN,tr|A0A7I2V433|A0A7I2V433_HUMAN,tr|A0A7I2V579|A0A7I2V579_HUMAN,tr|A0A7I2V2X9|A0A7I2V2X9_HUMAN,tr|A0A7I2V3G5|A0A7I2V3G5_HUMAN,tr|A0A7I2V5S2|A0A7I2V5S2_HUMAN,tr|A0A7I2V3U2|A0A7I2V3U2_HUMAN,tr|E5RGW4|E5RGW4_HUMAN" 10 1577.7309 0.98 114570 9848 3 1577.730773 526.9176 Nucleophosmin OS=Homo sapiens OX=9606 GN=NPM1 PE=1 SV=2 4.31 2031.5 - 1.59E+07 - - - -0.1014 - 3.18 0.687 - 566 1 2 0 -0.0002 13 0 0 0 1.32E+08 1.36E+08 - - - 9.336 1 221125_WJC_METTL3_EV_vs_WT_F08.09851.09851.3 8.06E-08 15/48 K.HETQSLALDAC[160.03]SR[166.11].D "sp|O75410|TACC1_HUMAN,tr|E7EVI4|E7EVI4_HUMAN,tr|E5RFM9|E5RFM9_HUMAN,tr|A0A0C4DGD5|A0A0C4DGD5_HUMAN,tr|R4GMT7|R4GMT7_HUMAN,tr|H0YAY0|H0YAY0_HUMAN,tr|A0A0C4DGD3|A0A0C4DGD3_HUMAN,tr|H0YBT8|H0YBT8_HUMAN,tr|E7ET87|E7ET87_HUMAN" 9 1496.6917 1.24 114573 9851 3 1496.695541 499.9045 Transforming acidic coiled-coil-containing protein 1 OS=Homo sapiens OX=9606 GN=TACC1 PE=1 SV=2 5.32 2031.6 - 1.29E+06 - - - 2.559 - 2.491 0.631 - 402.9 1 2 0 0.0038 13 0 0 0 2.51E+07 2.03E+07 - - - 8.0485 1 221125_WJC_METTL3_EV_vs_WT_F08.09853.09853.3 1.24E-06 Dec-44 K.TNNIFC[160.03]SNPNHR.T "sp|P29590|PML_HUMAN,tr|H3BT57|H3BT57_HUMAN" 2 1472.6579 1.05 114575 9853 3 1472.65965 491.8932 Protein PML OS=Homo sapiens OX=9606 GN=PML PE=1 SV=3 7.94 2031.8 - 929692 - - - 1.1917 - 2.657 0.519 - 202.3 1 2 0 0.0018 12 0 0 0 1.30E+07 1.24E+07 - - - 7.0345 1 221125_WJC_METTL3_EV_vs_WT_F08.09854.09854.3 9.20E-06 18/56 K.R[166.11]QAVTNPNNTFYATK[136.11].R "sp|P38646|GRP75_HUMAN,tr|H0Y8K0|H0Y8K0_HUMAN,tr|A0A7I2V2S7|A0A7I2V2S7_HUMAN,tr|A0A7I2V2G2|A0A7I2V2G2_HUMAN,tr|A0A3B3ITI4|A0A3B3ITI4_HUMAN,tr|A0A7I2V3F7|A0A7I2V3F7_HUMAN,tr|A0A7I2YQB2|A0A7I2YQB2_HUMAN,tr|D6RCD7|D6RCD7_HUMAN" 8 1741.8867 0.44 114576 9854 3 1741.890189 581.6362 "Stress-70 protein, mitochondrial OS=Homo sapiens OX=9606 GN=HSPA9 PE=1 SV=2" 9.99 2031.9 - 736375 - - - 2.0306 - 3.157 0.581 - 456.3 1 2 0 0.0035 15 0 0 0 5.90E+07 1.34E+08 - - - 8.0164 0.9973 221125_WJC_METTL3_EV_vs_WT_F08.09855.09855.3 0.000164 Nov-44 K.QVEEALHQLHAR[166.11].D "sp|O00233|PSMD9_HUMAN,tr|F5H169|F5H169_HUMAN,tr|J3KN29|J3KN29_HUMAN,tr|F5H5V4|F5H5V4_HUMAN,tr|F5GX23|F5GX23_HUMAN" 5 1439.7509 0.38 114577 9855 3 1439.758276 480.9242 26S proteasome non-ATPase regulatory subunit 9 OS=Homo sapiens OX=9606 GN=PSMD9 PE=1 SV=3 6 2032 - 501707 - - - 5.137 - 2.048 0.385 - 177.8 1 2 0 0.0074 12 0 0 0 2.41E+06 6.39E+06 - - - 4.8174 0.9999 221125_WJC_METTL3_EV_vs_WT_F08.09856.09856.3 1.08E-07 15/44 K.DLLHPSPEEEKR.K sp|P42677|RS27_HUMAN 1 1448.726 0.72 114578 9856 3 1448.729131 483.9159 40S ribosomal protein S27 OS=Homo sapiens OX=9606 GN=RPS27 PE=1 SV=3 4.83 2032.2 - 447563 - - - 2.1909 - 2.87 0.404 - 318.7 1 2 0 0.0032 12 0 0 0 4.50E+06 6.24E+06 - - - 5.9657 1 221125_WJC_METTL3_EV_vs_WT_F08.09858.09858.3 3.78E-06 Nov-48 K.DSSDPNELYVNHK[136.11].V "sp|O15160|RPAC1_HUMAN,tr|D6RDJ3|D6RDJ3_HUMAN,tr|A0A2R8YEZ4|A0A2R8YEZ4_HUMAN,tr|E7EQB9|E7EQB9_HUMAN,tr|A0A2R8Y5D3|A0A2R8Y5D3_HUMAN,tr|A0A2R8YEY5|A0A2R8YEY5_HUMAN" 6 1524.6936 0.25 114580 9858 3 1524.695164 509.2385 DNA-directed RNA polymerases I and III subunit RPAC1 OS=Homo sapiens OX=9606 GN=POLR1C PE=1 SV=1 4.54 2032.4 - 310661 - - - 1.0251 - 2 0.52 - 155.7 1 2 0 0.0016 13 0 0 0 3.06E+07 1.20E+08 - - - 6.2164 1 221125_WJC_METTL3_EV_vs_WT_F08.09860.09860.2 9.05E-09 Nov-36 K.ANDGEGGDEEAGTEEAVPR[166.11].R sp|Q9H3Q1|BORG4_HUMAN 1 1911.7958 1.85 114582 9860 2 1911.7974 956.9052 Cdc42 effector protein 4 OS=Homo sapiens OX=9606 GN=CDC42EP4 PE=1 SV=1 3.71 2032.7 - 148308 - - - 0.8484 - 2.499 0.672 - 233 1 2 0 0.0016 19 0 0 0 3.02E+06 1.63E+06 - - - 6.2556 1 221125_WJC_METTL3_EV_vs_WT_F08.09868.09868.2 3.50E-07 24-Sep K.HETQSLALDAC[160.03]SR[166.11].D "sp|O75410|TACC1_HUMAN,tr|E7EVI4|E7EVI4_HUMAN,tr|E5RFM9|E5RFM9_HUMAN,tr|A0A0C4DGD5|A0A0C4DGD5_HUMAN,tr|R4GMT7|R4GMT7_HUMAN,tr|H0YAY0|H0YAY0_HUMAN,tr|A0A0C4DGD3|A0A0C4DGD3_HUMAN,tr|H0YBT8|H0YBT8_HUMAN,tr|E7ET87|E7ET87_HUMAN" 9 1496.6917 1.38 114588 9868 2 1496.696917 749.3531 Transforming acidic coiled-coil-containing protein 1 OS=Homo sapiens OX=9606 GN=TACC1 PE=1 SV=2 5.32 2033.6 - 127471 - - - 3.4783 - 2.003 0.672 - 232 1 2 0 0.0052 13 0 0 0 2.03E+06 1.47E+06 - - - 5.7856 1 221125_WJC_METTL3_EV_vs_WT_F08.09873.09873.3 5.14E-09 18/56 K.RQAVTNPNNTFYATK.R "sp|P38646|GRP75_HUMAN,tr|H0Y8K0|H0Y8K0_HUMAN,tr|A0A7I2V2S7|A0A7I2V2S7_HUMAN,tr|A0A7I2V2G2|A0A7I2V2G2_HUMAN,tr|A0A3B3ITI4|A0A3B3ITI4_HUMAN,tr|A0A7I2V3F7|A0A7I2V3F7_HUMAN,tr|A0A7I2YQB2|A0A7I2YQB2_HUMAN,tr|D6RCD7|D6RCD7_HUMAN" 8 1723.8642 0.44 114591 9873 3 1723.867377 575.6287 "Stress-70 protein, mitochondrial OS=Homo sapiens OX=9606 GN=HSPA9 PE=1 SV=2" 9.99 2034.2 - 974326 - - - 1.8534 - 3.31 0.568 - 418.1 1 2 0 0.0032 15 0 0 0 5.89E+07 1.34E+08 - - - 7.995 0.9998 221125_WJC_METTL3_EV_vs_WT_F08.09874.09874.3 0.000969 Dec-44 R.VSVADHSLHLSK.A "sp|Q13162|PRDX4_HUMAN,tr|A6NG45|A6NG45_HUMAN" 2 1291.6885 0.57 114592 9874 3 1291.689129 431.5701 Peroxiredoxin-4 OS=Homo sapiens OX=9606 GN=PRDX4 PE=1 SV=1 6.89 2034.3 - 858844 - - - 0.5257 - 2.487 0.327 - 195.4 1 2 0 0.0007 12 0 0 0 6.11E+07 1.07E+08 - - - 4.7109 0.9997 221125_WJC_METTL3_EV_vs_WT_F08.09876.09876.3 0.00855 Oct-48 K.DSSDPNELYVNHK.V "sp|O15160|RPAC1_HUMAN,tr|D6RDJ3|D6RDJ3_HUMAN,tr|A0A2R8YEZ4|A0A2R8YEZ4_HUMAN,tr|E7EQB9|E7EQB9_HUMAN,tr|A0A2R8Y5D3|A0A2R8Y5D3_HUMAN,tr|A0A2R8YEY5|A0A2R8YEY5_HUMAN" 6 1516.6794 0.25 114594 9876 3 1516.680658 506.5671 DNA-directed RNA polymerases I and III subunit RPAC1 OS=Homo sapiens OX=9606 GN=POLR1C PE=1 SV=1 4.54 2034.5 - 370137 - - - 0.8288 - 1.829 0.376 - 131.8 1 2 0 0.0013 13 0 0 0 3.06E+07 1.20E+08 - - - 4.3687 0.9868 221125_WJC_METTL3_EV_vs_WT_F08.09877.09877.3 9.10E-06 16/48 G.HRLSPADDELYQR.T sp|Q9BU61|NDUF3_HUMAN 1 1598.7801 1.32 114595 9877 3 1598.781178 533.934 NADH dehydrogenase [ubiquinone] 1 alpha subcomplex assembly factor 3 OS=Homo sapiens OX=9606 GN=NDUFAF3 PE=1 SV=1 5.38 2034.6 - 314895 - - - 0.663 - 2.624 0.489 - 360.4 1 1 1 0.0011 13 0 0 0 1.65E+07 1.25E+07 - - - 6.6072 0.9164 221125_WJC_METTL3_EV_vs_WT_F08.09881.09881.2 3.79E-07 28-Sep R.SDSPVPTAPTSGGPK.P "sp|Q86U44|MTA70_HUMAN,tr|B4E349|B4E349_HUMAN,tr|F5H6D8|F5H6D8_HUMAN,tr|B4DTN4|B4DTN4_HUMAN" 4 1396.6834 0.02 114599 9881 2 1396.68897 699.349 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 5.55 2035.2 - 164728 - - - 3.9708 - 1.954 0.5 - 149.9 1 1 0 0.0055 15 0 0 0 1.86E+07 7.45E+08 - - - 4.3792 0.9998 221125_WJC_METTL3_EV_vs_WT_F08.09885.09885.3 4.46E-05 13/52 R.WPTGDNIHAEHQVR[166.11].S "sp|Q14671|PUM1_HUMAN,tr|Q5T1Z8|Q5T1Z8_HUMAN,tr|H0YEH2|H0YEH2_HUMAN,tr|Q5T1Z4|Q5T1Z4_HUMAN,tr|E9PR38|E9PR38_HUMAN" 5 1668.7996 2.2 114602 9885 3 1668.802957 557.2738 Pumilio homolog 1 OS=Homo sapiens OX=9606 GN=PUM1 PE=1 SV=3 5.99 2035.7 - 398153 - - - 1.9984 - 2.431 0.401 - 242.3 1 2 0 0.0033 14 0 0 0 7.14E+07 3.25E+07 - - - 5.3705 0.9998 221125_WJC_METTL3_EV_vs_WT_F08.09887.09887.3 0.00569 Nov-44 R.VSVADHSLHLSK[136.11].A "sp|Q13162|PRDX4_HUMAN,tr|A6NG45|A6NG45_HUMAN" 2 1299.7026 0.57 114603 9887 3 1299.705456 434.2415 Peroxiredoxin-4 OS=Homo sapiens OX=9606 GN=PRDX4 PE=1 SV=1 6.89 2035.9 - 4.96E+06 - - - 2.159 - 2.58 0.374 - 150.6 1 2 0 0.0028 12 0 0 0 6.11E+07 1.07E+08 - - - 5.3361 0.921 221125_WJC_METTL3_EV_vs_WT_F08.09888.09888.3 0.00812 Sep-40 V.SVADHSLHLSK.A "sp|Q13162|PRDX4_HUMAN,tr|A6NG45|A6NG45_HUMAN" 2 1192.62 0.57 114604 9888 3 1192.62057 398.5473 Peroxiredoxin-4 OS=Homo sapiens OX=9606 GN=PRDX4 PE=1 SV=1 6.66 2036 - 711888 - - - 0.4478 - 1.43 0.35 - 77.7 1 1 0 0.0005 11 0 0 0 1.43E+07 2.49E+07 - - - 3.4581 0.9999 221125_WJC_METTL3_EV_vs_WT_F08.09889.09889.2 8.06E-07 24-Nov K.DSSDPNELYVNHK[136.11].V "sp|O15160|RPAC1_HUMAN,tr|D6RDJ3|D6RDJ3_HUMAN,tr|A0A2R8YEZ4|A0A2R8YEZ4_HUMAN,tr|E7EQB9|E7EQB9_HUMAN,tr|A0A2R8Y5D3|A0A2R8Y5D3_HUMAN,tr|A0A2R8YEY5|A0A2R8YEY5_HUMAN" 6 1524.6936 0.17 114605 9889 2 1524.692375 763.3541 DNA-directed RNA polymerases I and III subunit RPAC1 OS=Homo sapiens OX=9606 GN=POLR1C PE=1 SV=1 4.54 2036.1 - 264104 - - - -0.8041 - 2.169 0.631 - 511 1 2 0 -0.0012 13 0 0 0 1.82E+06 1.09E+07 - - - 5.6884 0.9984 221125_WJC_METTL3_EV_vs_WT_F08.09892.09892.2 0.0274 26-Jun K.SNTEPQSPPIASPK.A "sp|P82094|TMF1_HUMAN,tr|F8WF45|F8WF45_HUMAN,tr|A0A2R8Y7M0|A0A2R8Y7M0_HUMAN" 3 1451.7256 5.41 114607 9892 2 1451.728568 726.8701 TATA element modulatory factor OS=Homo sapiens OX=9606 GN=TMF1 PE=1 SV=2 5.72 2036.5 - 105890 - - - 2.0286 - 1.268 0.417 - 99.5 1 2 0 0.0029 14 0 0 0 3.99E+06 7.38E+05 - - - 2.7159 0.9997 221125_WJC_METTL3_EV_vs_WT_F08.09895.09895.3 0.00784 13/56 R.DLIHGAPVGK[136.11]PAANR[166.11].A "sp|Q14683|SMC1A_HUMAN,tr|G8JLG1|G8JLG1_HUMAN,tr|A0A6Q8PHC3|A0A6Q8PHC3_HUMAN" 3 1532.8542 1.06 114609 9895 3 1532.857439 511.9587 Structural maintenance of chromosomes protein 1A OS=Homo sapiens OX=9606 GN=SMC1A PE=1 SV=2 8.75 2036.8 - 363173 - - - 2.0935 - 2.441 0.347 - 142.4 1 2 0 0.0032 15 0 0 0 4.73E+07 4.45E+07 - - - 4.7364 0.9962 221125_WJC_METTL3_EV_vs_WT_F08.09896.09896.4 0.00123 Sep-84 K.ILGVDK[136.11]NASEDEIK[136.11]K[136.11].A "sp|Q99615|DNJC7_HUMAN,tr|A0A6I8PRZ0|A0A6I8PRZ0_HUMAN,tr|A0A6I8PR89|A0A6I8PR89_HUMAN,tr|A0A6I8PIK4|A0A6I8PIK4_HUMAN,tr|A0A6I8PS32|A0A6I8PS32_HUMAN,tr|A0A6I8PUD4|A0A6I8PUD4_HUMAN,tr|K7ER44|K7ER44_HUMAN,tr|A0A6I8PU73|A0A6I8PU73_HUMAN" 8 1681.9313 0.67 114610 9896 4 1681.93225 421.4901 DnaJ homolog subfamily C member 7 OS=Homo sapiens OX=9606 GN=DNAJC7 PE=1 SV=2 4.78 2036.9 - 663177 - - - 0.585 - 2.082 0.323 - 33.3 2 2 1 0.001 15 0 0 0 6.31E+06 9.37E+06 - - - 2.0701 1 221125_WJC_METTL3_EV_vs_WT_F08.09898.09898.3 3.19E-08 21/48 G.HR[166.11]LSPADDELYQR[166.11].T sp|Q9BU61|NDUF3_HUMAN 1 1618.7967 1.32 114612 9898 3 1618.800987 540.6062 NADH dehydrogenase [ubiquinone] 1 alpha subcomplex assembly factor 3 OS=Homo sapiens OX=9606 GN=NDUFAF3 PE=1 SV=1 5.38 2037.2 - 516869 - - - 2.6742 - 4.353 0.577 - 1012.9 1 1 1 0.0043 13 0 0 0 1.65E+07 1.25E+07 - - - 8.9597 0.9997 221125_WJC_METTL3_EV_vs_WT_F08.09899.09899.4 0.000203 15/84 R.DLIHGAPVGK[136.11]PAANR[166.11].A "sp|Q14683|SMC1A_HUMAN,tr|G8JLG1|G8JLG1_HUMAN,tr|A0A6Q8PHC3|A0A6Q8PHC3_HUMAN" 3 1532.8542 0.03 114613 9899 4 1532.855491 384.2208 Structural maintenance of chromosomes protein 1A OS=Homo sapiens OX=9606 GN=SMC1A PE=1 SV=2 8.75 2037.3 - 327674 - - - 0.8226 - 2.305 0.348 - 138.8 1 2 0 0.0013 15 0 0 0 1.07E+06 3.31E+07 - - - 2.5534 0.9995 221125_WJC_METTL3_EV_vs_WT_F08.09900.09900.2 0.0111 13/22 R.VSVADHSLHLSK[136.11].A "sp|Q13162|PRDX4_HUMAN,tr|A6NG45|A6NG45_HUMAN" 2 1299.7026 0.48 114614 9900 2 1299.706805 650.8586 Peroxiredoxin-4 OS=Homo sapiens OX=9606 GN=PRDX4 PE=1 SV=1 6.89 2037.5 - 313020 - - - 3.1969 - 2.718 0.493 - 666.3 1 2 0 0.0042 12 0 0 0 3.03E+06 6.28E+06 - - - 5.3119 1 221125_WJC_METTL3_EV_vs_WT_F08.09902.09902.2 2.74E-11 Nov-36 K.ANDGEGGDEEAGTEEAVPR.R sp|Q9H3Q1|BORG4_HUMAN 1 1901.7875 1.85 114616 9902 2 1901.789001 951.901 Cdc42 effector protein 4 OS=Homo sapiens OX=9606 GN=CDC42EP4 PE=1 SV=1 3.71 2037.7 - 131328 - - - 0.7851 - 2.541 0.792 - 229.9 1 2 0 0.0015 19 0 0 0 3.02E+06 1.63E+06 - - - 7.183 0.9998 221125_WJC_METTL3_EV_vs_WT_F08.09907.09907.2 0.000167 14/28 K.R[166.11]QAVTNPNNTFYATK[136.11].R "sp|P38646|GRP75_HUMAN,tr|H0Y8K0|H0Y8K0_HUMAN,tr|A0A7I2V2S7|A0A7I2V2S7_HUMAN,tr|A0A7I2V2G2|A0A7I2V2G2_HUMAN,tr|A0A3B3ITI4|A0A3B3ITI4_HUMAN,tr|A0A7I2V3F7|A0A7I2V3F7_HUMAN,tr|A0A7I2YQB2|A0A7I2YQB2_HUMAN,tr|D6RCD7|D6RCD7_HUMAN" 8 1741.8867 0.38 114619 9907 2 1741.889367 871.9506 "Stress-70 protein, mitochondrial OS=Homo sapiens OX=9606 GN=HSPA9 PE=1 SV=2" 9.99 2038.4 - 270894 - - - 1.5587 - 2.915 0.522 - 502.1 1 2 0 0.0027 15 0 0 0 2.92E+06 7.77E+06 - - - 5.526 0.9985 221125_WJC_METTL3_EV_vs_WT_F08.09908.09908.3 0.324 Oct-52 R.TSDSTPDPQRVPLR.L "sp|P52948|NUP98_HUMAN,tr|H7C3P6|H7C3P6_HUMAN" 2 1567.7954 1.25 114620 9908 3 1567.797467 523.6058 Nuclear pore complex protein Nup98-Nup96 OS=Homo sapiens OX=9606 GN=NUP98 PE=1 SV=4 5.63 2038.5 - 1.02E+06 - - - 1.2967 - 2.08 0.346 - 105.8 1 2 1 0.002 14 0 0 0 2.80E+07 2.24E+07 - - - 4.3433 0.999 221125_WJC_METTL3_EV_vs_WT_F08.09909.09909.3 0.00045 Dec-56 K.ILGVDK[136.11]NASEDEIK[136.11]K[136.11].A "sp|Q99615|DNJC7_HUMAN,tr|A0A6I8PRZ0|A0A6I8PRZ0_HUMAN,tr|A0A6I8PR89|A0A6I8PR89_HUMAN,tr|A0A6I8PIK4|A0A6I8PIK4_HUMAN,tr|A0A6I8PS32|A0A6I8PS32_HUMAN,tr|A0A6I8PUD4|A0A6I8PUD4_HUMAN,tr|K7ER44|K7ER44_HUMAN,tr|A0A6I8PU73|A0A6I8PU73_HUMAN" 8 1681.9313 0.04 114621 9909 3 1681.932654 561.651 DnaJ homolog subfamily C member 7 OS=Homo sapiens OX=9606 GN=DNAJC7 PE=1 SV=2 4.78 2038.6 - 583152 - - - 0.8252 - 2.288 0.345 - 113.1 1 2 1 0.0014 15 0 0 0 3.27E+05 8.09E+06 - - - 4.5457 0.9998 221125_WJC_METTL3_EV_vs_WT_F08.09911.09911.2 5.39E-09 Nov-32 R.QDPPSVVVTSHQAPGEK.K sp|P25311|ZA2G_HUMAN 1 1774.885 999 114623 9911 2 1774.88762 888.4498 Zinc-alpha-2-glycoprotein OS=Homo sapiens OX=9606 GN=AZGP1 PE=1 SV=2 5.32 2038.8 - 140599 - - - 1.4891 - 2.309 0.595 - 182.5 1 2 0 0.0026 17 0 0 0 3.80E+06 0.00E+00 - - - 5.4922 0.984 221125_WJC_METTL3_EV_vs_WT_F08.09912.09912.2 1.75E-05 20-Jul S.SDPNELYVNHK[136.11].V "sp|O15160|RPAC1_HUMAN,tr|D6RDJ3|D6RDJ3_HUMAN,tr|A0A2R8YEZ4|A0A2R8YEZ4_HUMAN,tr|E7EQB9|E7EQB9_HUMAN,tr|A0A2R8Y5D3|A0A2R8Y5D3_HUMAN,tr|A0A2R8YEY5|A0A2R8YEY5_HUMAN" 6 1322.6346 1.05 114624 9912 2 1322.636454 662.3246 DNA-directed RNA polymerases I and III subunit RPAC1 OS=Homo sapiens OX=9606 GN=POLR1C PE=1 SV=1 5.3 2039 - 117754 - - - 1.3791 - 1.73 0.514 - 181.3 1 1 0 0.0018 11 0 0 0 7.33E+05 6.99E+05 - - - 4.3196 0.9999 221125_WJC_METTL3_EV_vs_WT_F08.09919.09919.2 2.81E-06 22-Oct R.VSVADHSLHLSK.A "sp|Q13162|PRDX4_HUMAN,tr|A6NG45|A6NG45_HUMAN" 2 1291.6885 0.48 114629 9919 2 1291.689387 646.8515 Peroxiredoxin-4 OS=Homo sapiens OX=9606 GN=PRDX4 PE=1 SV=1 6.89 2039.8 - 222851 - - - 0.7254 - 2.466 0.506 - 392.8 1 2 0 0.0009 12 0 0 0 3.03E+06 6.28E+06 - - - 5.1529 0.9998 221125_WJC_METTL3_EV_vs_WT_F08.09921.09921.2 8.94E-06 28-Sep K.RQAVTNPNNTFYATK.R "sp|P38646|GRP75_HUMAN,tr|H0Y8K0|H0Y8K0_HUMAN,tr|A0A7I2V2S7|A0A7I2V2S7_HUMAN,tr|A0A7I2V2G2|A0A7I2V2G2_HUMAN,tr|A0A3B3ITI4|A0A3B3ITI4_HUMAN,tr|A0A7I2V3F7|A0A7I2V3F7_HUMAN,tr|A0A7I2YQB2|A0A7I2YQB2_HUMAN,tr|D6RCD7|D6RCD7_HUMAN" 8 1723.8642 0.38 114631 9921 2 1723.864582 862.9394 "Stress-70 protein, mitochondrial OS=Homo sapiens OX=9606 GN=HSPA9 PE=1 SV=2" 9.99 2040.1 - 113023 - - - 0.232 - 1.933 0.502 - 141.9 1 2 0 0.0004 15 0 0 0 2.92E+06 7.77E+06 - - - 4.369 0.9996 221125_WJC_METTL3_EV_vs_WT_F08.09925.09925.4 0.00353 Nov-84 K.ILGVDKNASEDEIKK.A "sp|Q99615|DNJC7_HUMAN,tr|A0A6I8PRZ0|A0A6I8PRZ0_HUMAN,tr|A0A6I8PR89|A0A6I8PR89_HUMAN,tr|A0A6I8PIK4|A0A6I8PIK4_HUMAN,tr|A0A6I8PS32|A0A6I8PS32_HUMAN,tr|A0A6I8PUD4|A0A6I8PUD4_HUMAN,tr|K7ER44|K7ER44_HUMAN,tr|A0A6I8PU73|A0A6I8PU73_HUMAN" 8 1657.8887 0.67 114633 9925 4 1657.890583 415.4794 DnaJ homolog subfamily C member 7 OS=Homo sapiens OX=9606 GN=DNAJC7 PE=1 SV=2 4.78 2040.5 - 562883 - - - 1.1563 - 2.173 0.417 - 44.3 1 2 1 0.0019 15 0 0 0 6.28E+06 9.43E+06 - - - 3.1327 0.9597 221125_WJC_METTL3_EV_vs_WT_F08.09927.09927.3 4.41E-05 15/76 R.GDNQAGGAAAAAAAPEPPPR[166.11].S "sp|O14654|IRS4_HUMAN,tr|A0A804CF45|A0A804CF45_HUMAN" 2 1797.8633 1.38 114635 9927 3 1798.862995 600.2951 Insulin receptor substrate 4 OS=Homo sapiens OX=9606 GN=IRS4 PE=1 SV=1 4.37 2040.7 - 1.29E+06 - - - 556.0217 - 2.112 0.307 - 149.9 1 2 0 0.9997 20 0 0 0 9.18E+07 6.63E+07 - - - 3.4996 1 221125_WJC_METTL3_EV_vs_WT_F08.09932.09932.3 1.80E-07 17/56 R.DLIHGAPVGKPAANR.A "sp|Q14683|SMC1A_HUMAN,tr|G8JLG1|G8JLG1_HUMAN,tr|A0A6Q8PHC3|A0A6Q8PHC3_HUMAN" 3 1514.8318 1.06 114638 9932 3 1514.833954 505.9512 Structural maintenance of chromosomes protein 1A OS=Homo sapiens OX=9606 GN=SMC1A PE=1 SV=2 8.75 2041.3 - 2.55E+06 - - - 1.4483 - 2.896 0.601 - 293 1 2 0 0.0022 15 0 0 0 4.73E+07 4.45E+07 - - - 8.0146 0.9571 221125_WJC_METTL3_EV_vs_WT_F08.09933.09933.2 0.0078 14-Aug L.KWLDSDAR.N "sp|P34913|HYES_HUMAN,tr|E5RFU2|E5RFU2_HUMAN,tr|E5RFH6|E5RFH6_HUMAN" 3 989.493 24.4 114639 9933 2 989.494097 495.7538 Bifunctional epoxide hydrolase 2 OS=Homo sapiens OX=9606 GN=EPHX2 PE=1 SV=2 5.96 2041.4 - 2.28E+06 - - - 1.0642 - 1.605 0.334 - 388.9 1 1 0 0.0011 8 0 0 0 9.94E+07 4.08E+06 - - - 2.9345 0.9991 221125_WJC_METTL3_EV_vs_WT_F08.09936.09936.3 0.0164 Oct-60 R.NSLPASPAHQLSSSPR[166.11].L sp|Q8TEK3|DOT1L_HUMAN 1 1657.8412 2.85 114642 9936 3 1657.842772 553.621 "Histone-lysine N-methyltransferase, H3 lysine-79 specific OS=Homo sapiens OX=9606 GN=DOT1L PE=1 SV=3" 9.76 2041.6 - 605272 - - - 0.9772 - 1.994 0.31 - 80.6 4 2 0 0.0016 16 0 0 0 6.37E+07 2.24E+07 - - - 3.4879 0.9999 221125_WJC_METTL3_EV_vs_WT_F08.09942.09942.3 0.000443 Dec-44 R.KPHTESLELQVR.G sp|Q9BSJ8|ESYT1_HUMAN 1 1435.7783 0.93 114646 9942 3 1435.780983 479.6001 Extended synaptotagmin-1 OS=Homo sapiens OX=9606 GN=ESYT1 PE=1 SV=1 6.76 2042.4 - 440160 - - - 1.8499 - 2.717 0.41 - 275.3 1 2 0 0.0027 12 0 0 0 9.80E+06 1.05E+07 - - - 5.8809 0.9958 221125_WJC_METTL3_EV_vs_WT_F08.09947.09947.3 1.26E-06 17/52 K.HALLEADVAAHQDR.L "sp|Q13813|SPTN1_HUMAN,tr|A0A0D9SF54|A0A0D9SF54_HUMAN,tr|A0A0D9SGF6|A0A0D9SGF6_HUMAN" 3 1544.7696 1.04 114651 9947 3 1545.78048 515.9305 "Spectrin alpha chain, non-erythrocytic 1 OS=Homo sapiens OX=9606 GN=SPTAN1 PE=1 SV=3" 5.21 2043 - 221576 - - - 654.4193 - 3.755 0.595 - 412.8 1 2 0 1.0109 14 0 0 0 6.76E+06 6.50E+06 - - - 8.4098 1 221125_WJC_METTL3_EV_vs_WT_F08.09950.09950.2 5.44E-16 20/38 R.GDNQAGGAAAAAAAPEPPPR.S "sp|O14654|IRS4_HUMAN,tr|A0A804CF45|A0A804CF45_HUMAN" 2 1787.8551 1.45 114653 9950 2 1787.854862 894.9348 Insulin receptor substrate 4 OS=Homo sapiens OX=9606 GN=IRS4 PE=1 SV=1 4.37 2043.3 - 371536 - - - -0.1186 - 3.743 0.796 - 817.9 1 2 0 -0.0002 20 0 0 0 2.74E+07 1.89E+07 - - - 8.1652 0.9998 221125_WJC_METTL3_EV_vs_WT_F08.09951.09951.2 0.000104 26-Oct K.QVQPQLQQEAEPQK[136.11].Q "sp|Q9ULV3|CIZ1_HUMAN,tr|Q5SYW2|Q5SYW2_HUMAN,tr|F5H2X7|F5H2X7_HUMAN,tr|H0Y5D5|H0Y5D5_HUMAN,tr|A0A494C0L7|A0A494C0L7_HUMAN,tr|Q9BTG3|Q9BTG3_HUMAN" 6 1657.8515 3.13 114654 9951 2 1657.850793 829.933 Cip1-interacting zinc finger protein OS=Homo sapiens OX=9606 GN=CIZ1 PE=1 SV=2 4.53 2043.5 - 233877 - - - -0.4259 - 1.938 0.477 - 254.8 1 2 0 -0.0007 14 0 0 0 8.12E+07 2.59E+07 - - - 4.2243 0.9999 221125_WJC_METTL3_EV_vs_WT_F08.09953.09953.3 3.31E-05 14/56 R.VDEVPDGAVKPPTNK.L sp|O75475|PSIP1_HUMAN 1 1564.8097 1.17 114656 9953 3 1564.810941 522.6105 PC4 and SFRS1-interacting protein OS=Homo sapiens OX=9606 GN=PSIP1 PE=1 SV=1 4.56 2043.6 - 367449 - - - 0.8014 - 2.424 0.419 - 246 1 2 0 0.0013 15 0 0 0 2.66E+07 2.28E+07 - - - 5.5215 0.9999 221125_WJC_METTL3_EV_vs_WT_F08.09954.09954.3 7.48E-07 Dec-68 R.LGMSADPDNEDATDK[136.11]VNK[136.11].V "sp|O75152|ZC11A_HUMAN,tr|E9PBY7|E9PBY7_HUMAN,tr|E9PQ61|E9PQ61_HUMAN" 3 1934.8862 1.17 114657 9954 3 1934.885391 645.9694 Zinc finger CCCH domain-containing protein 11A OS=Homo sapiens OX=9606 GN=ZC3H11A PE=1 SV=3 4.04 2043.8 - 271048 - - - -0.4367 - 2.439 0.569 - 174.2 1 2 1 -0.0008 18 0 0 0 7.78E+06 6.65E+06 - - - 7.1037 0.9989 221125_WJC_METTL3_EV_vs_WT_F08.09955.09955.3 0.00438 Oct-60 K.ALTESTLPK[136.11]PVQK[136.11]PPK[136.11].S "sp|Q9NUL3|STAU2_HUMAN,tr|E5RGQ5|E5RGQ5_HUMAN,tr|E7EVJ4|E7EVJ4_HUMAN,tr|E7EVI1|E7EVI1_HUMAN,tr|E7EPX0|E7EPX0_HUMAN,tr|E5RGT3|E5RGT3_HUMAN,tr|E5RFK1|E5RFK1_HUMAN" 7 1757.0513 1.79 114658 9955 3 1757.054129 586.6911 Double-stranded RNA-binding protein Staufen homolog 2 OS=Homo sapiens OX=9606 GN=STAU2 PE=1 SV=2 9.7 2043.9 - 236285 - - - 1.5981 - 1.59 0.344 - 75.6 1 2 0 0.0028 16 0 0 0 8.73E+06 4.86E+06 - - - 3.5644 0.9976 221125_WJC_METTL3_EV_vs_WT_F08.09956.09956.3 0.00699 Aug-36 R.QAVDVSPLR[166.11]R[166.11].V "sp|P46782|RS5_HUMAN,tr|M0QZN2|M0QZN2_HUMAN,tr|M0R0F0|M0R0F0_HUMAN,tr|M0R0R2|M0R0R2_HUMAN" 4 1159.6576 0.92 114659 9956 3 1159.657589 387.5598 40S ribosomal protein S5 OS=Homo sapiens OX=9606 GN=RPS5 PE=1 SV=4 9.6 2044 - 178956 - - - -0.0483 - 1.637 0.245 - 136.2 1 2 0 -0.0001 10 0 0 0 3.67E+06 3.99E+06 - - - 2.7109 0.9997 221125_WJC_METTL3_EV_vs_WT_F08.09958.09958.3 2.65E-06 16/52 K.HALLEADVAAHQDR[166.11].L "sp|Q13813|SPTN1_HUMAN,tr|A0A0D9SF54|A0A0D9SF54_HUMAN,tr|A0A0D9SGF6|A0A0D9SGF6_HUMAN" 3 1554.7778 1.11 114660 9958 3 1554.78636 519.2666 "Spectrin alpha chain, non-erythrocytic 1 OS=Homo sapiens OX=9606 GN=SPTAN1 PE=1 SV=3" 5.21 2044.2 - 403842 - - - 5.4902 - 3.189 0.564 - 297.5 1 2 0 0.0085 14 0 0 0 7.32E+06 6.62E+06 - - - 7.9076 0.9998 221125_WJC_METTL3_EV_vs_WT_F08.09960.09960.3 9.64E-07 Dec-44 R.DDDK[136.11]AK[136.11]PGFLPK[136.11].G "sp|Q9Y520|PRC2C_HUMAN,tr|E7EPN9|E7EPN9_HUMAN" 2 1353.7355 3.51 114661 9960 3 1353.737498 452.2524 Protein PRRC2C OS=Homo sapiens OX=9606 GN=PRRC2C PE=1 SV=4 6.04 2044.5 - 2.44E+06 - - - 1.501 - 2.404 0.503 - 142.3 1 2 1 0.002 12 0 0 0 3.09E+08 8.80E+07 - - - 6.5787 0.9872 221125_WJC_METTL3_EV_vs_WT_F08.09967.09967.3 0.0089 Oct-56 R.VEEEEERNQILQNEK.K sp|P35580|MYH10_HUMAN 1 1885.9017 0.82 114666 9967 3 1885.909401 629.6412 Myosin-10 OS=Homo sapiens OX=9606 GN=MYH10 PE=1 SV=3 4.21 2045.3 - 939006 - - - 4.0569 - 2.117 0.326 - 111 1 2 1 0.0077 15 0 0 0 1.06E+07 1.30E+07 - - - 4.1295 0.9988 221125_WJC_METTL3_EV_vs_WT_F08.09970.09970.4 0.000785 16/90 K.ALTESTLPKPVQKPPK.S "sp|Q9NUL3|STAU2_HUMAN,tr|E5RGQ5|E5RGQ5_HUMAN,tr|E7EVJ4|E7EVJ4_HUMAN,tr|E7EVI1|E7EVI1_HUMAN,tr|E7EPX0|E7EPX0_HUMAN,tr|E5RGT3|E5RGT3_HUMAN,tr|E5RFK1|E5RFK1_HUMAN" 7 1733.0087 2.23 114669 9970 4 1733.014157 434.2595 Double-stranded RNA-binding protein Staufen homolog 2 OS=Homo sapiens OX=9606 GN=STAU2 PE=1 SV=2 9.7 2045.6 - 848475 - - - 3.1367 - 2.289 0.346 - 167.7 1 2 0 0.0054 16 0 0 0 2.81E+07 1.26E+07 - - - 2.5278 0.9994 221125_WJC_METTL3_EV_vs_WT_F08.09971.09971.3 0.00133 15/56 R.K[136.11]IQALQQQADEAEDR[166.11].A "sp|P67936|TPM4_HUMAN,tr|A0A590UJB9|A0A590UJB9_HUMAN,tr|A0A2R8Y5V9|A0A2R8Y5V9_HUMAN,tr|A0A2R8YGX3|A0A2R8YGX3_HUMAN,tr|A0A590UK79|A0A590UK79_HUMAN" 5 1759.882 0.85 114670 9971 3 1759.889063 587.6346 Tropomyosin alpha-4 chain OS=Homo sapiens OX=9606 GN=TPM4 PE=1 SV=3 4.32 2045.7 - 383621 - - - 4.0355 - 2.533 0.401 - 361.7 1 2 0 0.0071 15 0 0 0 6.11E+06 7.22E+06 - - - 5.4339 1 221125_WJC_METTL3_EV_vs_WT_F08.09972.09972.3 2.00E-07 15/60 K.ALTESTLPKPVQKPPK.S "sp|Q9NUL3|STAU2_HUMAN,tr|E5RGQ5|E5RGQ5_HUMAN,tr|E7EVJ4|E7EVJ4_HUMAN,tr|E7EVI1|E7EVI1_HUMAN,tr|E7EPX0|E7EPX0_HUMAN,tr|E5RGT3|E5RGT3_HUMAN,tr|E5RFK1|E5RFK1_HUMAN" 7 1733.0087 1.79 114671 9972 3 1733.011232 578.6769 Double-stranded RNA-binding protein Staufen homolog 2 OS=Homo sapiens OX=9606 GN=STAU2 PE=1 SV=2 9.7 2045.8 - 374789 - - - 1.4489 - 2.699 0.53 - 284.2 1 2 0 0.0025 16 0 0 0 8.73E+06 4.86E+06 - - - 6.9959 0.9999 221125_WJC_METTL3_EV_vs_WT_F08.09973.09973.3 5.18E-06 14/56 R.VDEVPDGAVK[136.11]PPTNK[136.11].L sp|O75475|PSIP1_HUMAN 1 1580.8381 -1 114672 9973 3 1580.84178 527.9533 PC4 and SFRS1-interacting protein OS=Homo sapiens OX=9606 GN=PSIP1 PE=1 SV=1 4.56 2046 - 371140 - - - 2.3361 - 2.626 0.533 - 199.8 1 2 0 0.0037 15 0 0 0 0.00E+00 0.00E+00 - - - 7.0006 0.9999 221125_WJC_METTL3_EV_vs_WT_F08.09974.09974.4 1.64E-05 Oct-84 K.R[166.11]PAVASAR[166.11]PSILPSK[136.11].D "sp|P27816|MAP4_HUMAN,tr|E7EVA0|E7EVA0_HUMAN,tr|H7C4C5|H7C4C5_HUMAN,tr|A0A804HKE7|A0A804HKE7_HUMAN,tr|B5MEG9|B5MEG9_HUMAN" 5 1576.9407 0.42 114673 9974 4 1576.939505 395.2425 Microtubule-associated protein 4 OS=Homo sapiens OX=9606 GN=MAP4 PE=1 SV=3 12.01 2046.1 - 238621 - - - -0.7895 - 2.183 0.441 - 99.4 1 2 0 -0.0012 15 0 0 0 1.61E+06 3.84E+06 - - - 3.3435 0.9999 221125_WJC_METTL3_EV_vs_WT_F08.09975.09975.2 6.66E-06 22-Nov K.EQYQQQQQWGSR.G "sp|Q14103|HNRPD_HUMAN,tr|H0Y8G5|H0Y8G5_HUMAN,tr|H0YA96|H0YA96_HUMAN" 3 1564.7019 1.08 114674 9975 2 1564.703712 783.3582 Heterogeneous nuclear ribonucleoprotein D0 OS=Homo sapiens OX=9606 GN=HNRNPD PE=1 SV=1 6.1 2046.2 - 225718 - - - 1.1785 - 2.32 0.583 - 540.8 1 2 0 0.0018 12 0 0 0 2.57E+06 2.37E+06 - - - 5.5608 1 221125_WJC_METTL3_EV_vs_WT_F08.09978.09978.3 1.82E-10 22/64 R.QDPPSVVVTSHQAPGEK.K sp|P25311|ZA2G_HUMAN 1 1774.885 593.63 114676 9978 3 1774.887682 592.6356 Zinc-alpha-2-glycoprotein OS=Homo sapiens OX=9606 GN=AZGP1 PE=1 SV=2 5.32 2046.6 - 8.15E+06 - - - 1.524 - 3.736 0.555 - 774.1 1 2 0 0.0027 17 0 0 0 3.33E+08 5.61E+05 - - - 8.0567 1 221125_WJC_METTL3_EV_vs_WT_F08.09980.09980.3 5.70E-07 13/48 K.LHVGNISPTC[160.03]TNK[136.11].E "sp|Q9BWF3|RBM4_HUMAN,tr|D6R9K7|D6R9K7_HUMAN,tr|J3QRR5|J3QRR5_HUMAN,tr|E9PB51|E9PB51_HUMAN" 4 1447.7333 1.29 114678 9980 3 1447.736206 483.585 RNA-binding protein 4 OS=Homo sapiens OX=9606 GN=RBM4 PE=1 SV=1 8.23 2046.8 - 2.33E+06 - - - 2.0087 - 2.451 0.536 - 354.3 1 2 0 0.0029 13 0 0 0 8.88E+07 6.90E+07 - - - 6.9457 0.997 221125_WJC_METTL3_EV_vs_WT_F08.09981.09981.3 5.79E-05 14/60 K.TVNQQTMAAPVVK[136.11]EEK[136.11].Q "sp|Q9Y520|PRC2C_HUMAN,tr|E7EPN9|E7EPN9_HUMAN" 2 1787.9422 0.88 114679 9981 3 1787.944171 596.988 Protein PRRC2C OS=Homo sapiens OX=9606 GN=PRRC2C PE=1 SV=4 5.81 2046.8 - 1.68E+06 - - - 1.0828 - 2.067 0.297 - 177.1 1 2 1 0.0019 16 0 0 0 2.32E+07 2.65E+07 - - - 3.7138 1 221125_WJC_METTL3_EV_vs_WT_F08.09982.09982.3 3.02E-06 Dec-44 R.TLVAVKPDGVQR.R "sp|O00746|NDKM_HUMAN,tr|Q4TT34|Q4TT34_HUMAN,tr|A0A087WVT9|A0A087WVT9_HUMAN,tr|H0Y6J0|H0Y6J0_HUMAN,tr|F2Z2X0|F2Z2X0_HUMAN" 5 1281.7405 0.96 114680 9982 3 1281.742172 428.2541 "Nucleoside diphosphate kinase, mitochondrial OS=Homo sapiens OX=9606 GN=NME4 PE=1 SV=1" 8.41 2046.9 - 1.03E+06 - - - 1.3162 - 2.308 0.537 - 142.2 1 2 0 0.0017 12 0 0 0 2.40E+07 2.50E+07 - - - 6.8449 0.9998 221125_WJC_METTL3_EV_vs_WT_F08.09983.09983.3 0.000913 15/68 R.LGMSADPDNEDATDKVNK.V "sp|O75152|ZC11A_HUMAN,tr|E9PBY7|E9PBY7_HUMAN,tr|E9PQ61|E9PQ61_HUMAN" 3 1918.8578 1.17 114681 9983 3 1918.860144 640.6266 Zinc finger CCCH domain-containing protein 11A OS=Homo sapiens OX=9606 GN=ZC3H11A PE=1 SV=3 4.04 2047 - 720557 - - - 1.2028 - 2.817 0.495 - 234 1 2 1 0.0023 18 0 0 0 7.78E+06 6.65E+06 - - - 6.6371 0.9999 221125_WJC_METTL3_EV_vs_WT_F08.09984.09984.4 0.000203 13/90 K.ALTESTLPK[136.11]PVQK[136.11]PPK[136.11].S "sp|Q9NUL3|STAU2_HUMAN,tr|E5RGQ5|E5RGQ5_HUMAN,tr|E7EVJ4|E7EVJ4_HUMAN,tr|E7EVI1|E7EVI1_HUMAN,tr|E7EPX0|E7EPX0_HUMAN,tr|E5RGT3|E5RGT3_HUMAN,tr|E5RFK1|E5RFK1_HUMAN" 7 1757.0513 1.5 114682 9984 4 1757.054675 440.2701 Double-stranded RNA-binding protein Staufen homolog 2 OS=Homo sapiens OX=9606 GN=STAU2 PE=1 SV=2 9.7 2047.1 - 513619 - - - 1.9089 - 1.913 0.435 - 98.6 1 2 0 0.0034 16 0 0 0 1.37E+07 9.11E+06 - - - 3.2398 1 221125_WJC_METTL3_EV_vs_WT_F08.09985.09985.2 1.12E-07 14/24 K.LHVGNISPTC[160.03]TNK.E "sp|Q9BWF3|RBM4_HUMAN,tr|D6R9K7|D6R9K7_HUMAN,tr|J3QRR5|J3QRR5_HUMAN,tr|E9PB51|E9PB51_HUMAN" 4 1439.7191 1.33 114683 9985 2 1439.720782 720.8668 RNA-binding protein 4 OS=Homo sapiens OX=9606 GN=RBM4 PE=1 SV=1 8.23 2047.3 - 335557 - - - 1.1697 - 2.794 0.605 - 638.9 1 2 0 0.0017 13 0 0 0 1.11E+07 8.34E+06 - - - 6.146 1 221125_WJC_METTL3_EV_vs_WT_F08.09986.09986.3 2.42E-05 16/68 K.IGQQPQQPGAPPQQDYTK.A "sp|Q92945|FUBP2_HUMAN,tr|M0R0C6|M0R0C6_HUMAN,tr|M0QYG1|M0QYG1_HUMAN,tr|A0A087WTP3|A0A087WTP3_HUMAN" 4 1979.9701 1.27 114684 9986 3 1979.970455 660.9973 Far upstream element-binding protein 2 OS=Homo sapiens OX=9606 GN=KHSRP PE=1 SV=4 5.83 2047.4 - 244397 - - - 0.1773 - 2.486 0.502 - 234.7 1 2 0 0.0004 18 0 0 0 5.18E+07 4.07E+07 - - - 6.4044 0.9999 221125_WJC_METTL3_EV_vs_WT_F08.09987.09987.2 9.74E-09 28-Oct K.VSYGIGDEEHDQEGR[166.11].V "sp|P27695|APEX1_HUMAN,tr|G3V3C7|G3V3C7_HUMAN,tr|G3V5M0|G3V5M0_HUMAN,tr|G3V3M6|G3V3M6_HUMAN,tr|G3V359|G3V359_HUMAN" 5 1699.7313 0.001 114685 9987 2 1699.733013 850.8729 DNA-(apurinic or apyrimidinic site) endonuclease OS=Homo sapiens OX=9606 GN=APEX1 PE=1 SV=2 4.17 2047.5 - 124839 - - - 0.9919 - 2.157 0.555 - 256.8 1 2 0 0.0017 15 0 0 0 0.00E+00 7.82E+05 - - - 5.0296 0.9875 221125_WJC_METTL3_EV_vs_WT_F08.09988.09988.2 5.20E-05 22-Jul K.EQYQQQQQWGSR[166.11].G "sp|Q14103|HNRPD_HUMAN,tr|H0Y8G5|H0Y8G5_HUMAN,tr|H0YA96|H0YA96_HUMAN" 3 1574.7101 1.08 114686 9988 2 1575.710669 788.3623 Heterogeneous nuclear ribonucleoprotein D0 OS=Homo sapiens OX=9606 GN=HNRNPD PE=1 SV=1 6.1 2047.7 - 121640 - - - 635.3747 - 1.923 0.53 - 166.8 1 2 0 1.0005 12 0 0 0 2.57E+06 2.37E+06 - - - 4.3619 1 221125_WJC_METTL3_EV_vs_WT_F08.09991.09991.3 2.04E-08 15/56 K.VSYGIGDEEHDQEGR.V "sp|P27695|APEX1_HUMAN,tr|G3V3C7|G3V3C7_HUMAN,tr|G3V5M0|G3V5M0_HUMAN,tr|G3V3M6|G3V3M6_HUMAN,tr|G3V359|G3V359_HUMAN" 5 1689.7231 0.14 114687 9991 3 1689.726172 564.2483 DNA-(apurinic or apyrimidinic site) endonuclease OS=Homo sapiens OX=9606 GN=APEX1 PE=1 SV=2 4.17 2048.1 - 609462 - - - 1.8435 - 2.928 0.61 - 252.3 1 2 0 0.0031 15 0 0 0 7.04E+06 4.90E+07 - - - 8.1433 0.9917 221125_WJC_METTL3_EV_vs_WT_F08.09992.09992.3 0.0133 Nov-60 R.SFGTEDRPTDRPIPPR.D "sp|Q8ND56|LS14A_HUMAN,tr|I3L4Q1|I3L4Q1_HUMAN,tr|A0A140TA76|A0A140TA76_HUMAN,tr|K7EMZ9|K7EMZ9_HUMAN" 4 1839.9228 1.04 114688 9992 3 1839.926444 614.3149 Protein LSM14 homolog A OS=Homo sapiens OX=9606 GN=LSM14A PE=1 SV=3 5.84 2048.2 - 719274 - - - 2.0023 - 1.58 0.235 - 66 1 2 0 0.0037 16 0 0 0 3.80E+07 3.67E+07 - - - 2.3327 0.9931 221125_WJC_METTL3_EV_vs_WT_F08.09993.09993.3 0.0177 Oct-44 R.VTK[136.11]PNIPEAIR[166.11]R[166.11].N "sp|O94905|ERLN2_HUMAN,tr|E5RHW4|E5RHW4_HUMAN,tr|E5RJ09|E5RJ09_HUMAN" 3 1420.8509 1.41 114689 9993 3 1420.851171 474.6242 Erlin-2 OS=Homo sapiens OX=9606 GN=ERLIN2 PE=1 SV=1 10.83 2048.3 - 626101 - - - 0.2104 - 1.682 0.184 - 76.9 1 2 0 0.0003 12 0 0 0 2.26E+07 1.60E+07 - - - 2.0327 1 221125_WJC_METTL3_EV_vs_WT_F08.09994.09994.3 1.05E-07 21/68 K.IGQQPQQPGAPPQQDYTK[136.11].A "sp|Q92945|FUBP2_HUMAN,tr|M0R0C6|M0R0C6_HUMAN,tr|M0QYG1|M0QYG1_HUMAN,tr|A0A087WTP3|A0A087WTP3_HUMAN" 4 1987.9843 1.27 114690 9994 3 1987.986035 663.6687 Far upstream element-binding protein 2 OS=Homo sapiens OX=9606 GN=KHSRP PE=1 SV=4 5.83 2048.4 - 460561 - - - 0.8707 - 3.431 0.585 - 635.2 1 2 0 0.0017 18 0 0 0 5.06E+07 3.98E+07 - - - 8.1316 1 221125_WJC_METTL3_EV_vs_WT_F08.09997.09997.2 3.16E-08 Nov-38 R.GDNQAGGAAAAAAAPEPPPR[166.11].S "sp|O14654|IRS4_HUMAN,tr|A0A804CF45|A0A804CF45_HUMAN" 2 1797.8633 1.46 114693 9997 2 1797.856927 899.9389 Insulin receptor substrate 4 OS=Homo sapiens OX=9606 GN=IRS4 PE=1 SV=1 4.37 2048.8 - 180289 - - - -3.5692 - 2.227 0.641 - 214.9 1 2 0 -0.0064 20 0 0 0 2.69E+07 1.84E+07 - - - 5.7419 0.9994 221125_WJC_METTL3_EV_vs_WT_F08.09999.09999.2 0.00079 Jul-34 K.IGQQPQQPGAPPQQDYTK[136.11].A "sp|Q92945|FUBP2_HUMAN,tr|M0R0C6|M0R0C6_HUMAN,tr|M0QYG1|M0QYG1_HUMAN,tr|A0A087WTP3|A0A087WTP3_HUMAN" 4 1987.9843 1.33 114695 9999 2 1987.988712 994.9994 Far upstream element-binding protein 2 OS=Homo sapiens OX=9606 GN=KHSRP PE=1 SV=4 5.83 2049 - 89926.1 - - - 2.2173 - 1.757 0.482 - 97.5 1 2 0 0.0044 18 0 0 0 1.30E+07 9.79E+06 - - - 3.9853 0.9977 221125_WJC_METTL3_EV_vs_WT_F08.10001.10001.4 0.00603 Dec-90 R.SFGTEDRPTDRPIPPR.D "sp|Q8ND56|LS14A_HUMAN,tr|I3L4Q1|I3L4Q1_HUMAN,tr|A0A140TA76|A0A140TA76_HUMAN,tr|K7EMZ9|K7EMZ9_HUMAN" 4 1839.9228 0.99 114696 10001 4 1839.925857 460.988 Protein LSM14 homolog A OS=Homo sapiens OX=9606 GN=LSM14A PE=1 SV=3 5.84 2049.3 - 1.69E+06 - - - 1.6832 - 1.695 0.277 - 86.2 1 2 0 0.0031 16 0 0 0 2.36E+07 2.39E+07 - - - 1.822 0.9999 221125_WJC_METTL3_EV_vs_WT_F08.10002.10002.3 0.000725 19/52 K.SK[136.11]AELMEISEDK[136.11]TK[136.11].L "sp|P05455|LA_HUMAN,tr|E9PGX9|E9PGX9_HUMAN,tr|E9PFL9|E9PFL9_HUMAN,tr|E7ERC4|E7ERC4_HUMAN" 4 1631.8502 1.11 114697 10002 3 1631.851132 544.9574 Lupus La protein OS=Homo sapiens OX=9606 GN=SSB PE=1 SV=2 4.87 2049.3 - 2.01E+06 - - - 0.5478 - 3.33 0.555 - 488 1 2 2 0.0009 14 0 0 0 3.33E+07 3.00E+07 - - - 7.9244 0.9801 221125_WJC_METTL3_EV_vs_WT_F08.10003.10003.3 0.0156 Oct-44 R.VTKPNIPEAIRR.N "sp|O94905|ERLN2_HUMAN,tr|E5RHW4|E5RHW4_HUMAN,tr|E5RJ09|E5RJ09_HUMAN" 3 1392.8201 1.42 114698 10003 3 1392.823088 465.2807 Erlin-2 OS=Homo sapiens OX=9606 GN=ERLIN2 PE=1 SV=1 10.83 2049.4 - 1.16E+06 - - - 2.1223 - 1.832 0.145 - 105.8 1 2 0 0.003 12 0 0 0 2.27E+07 1.60E+07 - - - 1.8339 0.9995 221125_WJC_METTL3_EV_vs_WT_F08.10004.10004.4 0.000447 14/78 K.SK[136.11]AELMEISEDK[136.11]TK[136.11].L "sp|P05455|LA_HUMAN,tr|E9PGX9|E9PGX9_HUMAN,tr|E9PFL9|E9PFL9_HUMAN,tr|E7ERC4|E7ERC4_HUMAN" 4 1631.8502 0.94 114699 10004 4 1631.853746 408.9698 Lupus La protein OS=Homo sapiens OX=9606 GN=SSB PE=1 SV=2 4.87 2049.5 - 1.15E+06 - - - 2.1497 - 2.225 0.45 - 109.6 1 2 2 0.0035 14 0 0 0 1.52E+07 1.61E+07 - - - 3.4329 0.9935 221125_WJC_METTL3_EV_vs_WT_F08.10005.10005.4 0.0127 Dec-78 K.SKAELMEISEDKTK.L "sp|P05455|LA_HUMAN,tr|E9PGX9|E9PGX9_HUMAN,tr|E9PFL9|E9PFL9_HUMAN,tr|E7ERC4|E7ERC4_HUMAN" 4 1607.8076 0.95 114700 10005 4 1607.810311 402.9592 Lupus La protein OS=Homo sapiens OX=9606 GN=SSB PE=1 SV=2 4.87 2049.6 - 928653 - - - 1.6625 - 2.002 0.284 - 108.7 1 2 2 0.0027 14 0 0 0 1.53E+07 1.61E+07 - - - 1.9498 0.9999 221125_WJC_METTL3_EV_vs_WT_F08.10009.10009.3 3.89E-08 15/60 K.TVNQQTMAAPVVKEEK.Q "sp|Q9Y520|PRC2C_HUMAN,tr|E7EPN9|E7EPN9_HUMAN" 2 1771.9138 0.88 114702 10009 3 1771.91736 591.6452 Protein PRRC2C OS=Homo sapiens OX=9606 GN=PRRC2C PE=1 SV=4 5.81 2050.1 - 2.37E+06 - - - 1.9894 - 2.783 0.618 - 219.8 1 2 1 0.0035 16 0 0 0 2.32E+07 2.65E+07 - - - 8.0553 0.9713 221125_WJC_METTL3_EV_vs_WT_F08.10010.10010.4 0.0681 Nov-90 R.SFGTEDR[166.11]PTDR[166.11]PIPPR[166.11].D "sp|Q8ND56|LS14A_HUMAN,tr|I3L4Q1|I3L4Q1_HUMAN,tr|A0A140TA76|A0A140TA76_HUMAN,tr|K7EMZ9|K7EMZ9_HUMAN" 4 1869.9476 1.08 114703 10010 4 1869.952642 468.4942 Protein LSM14 homolog A OS=Homo sapiens OX=9606 GN=LSM14A PE=1 SV=3 5.84 2050.2 - 1.29E+06 - - - 2.7124 - 1.717 0.196 - 71.7 1 2 0 0.0051 16 0 0 0 1.04E+07 9.57E+06 - - - 1.121 0.9998 221125_WJC_METTL3_EV_vs_WT_F08.10011.10011.3 2.15E-08 20/48 R.FREDHPDLIQNAK.K "sp|P17480|UBF1_HUMAN,tr|E9PKP7|E9PKP7_HUMAN" 2 1581.79 1.44 114704 10011 3 1581.78513 528.2706 Nucleolar transcription factor 1 OS=Homo sapiens OX=9606 GN=UBTF PE=1 SV=1 5.38 2050.2 - 666042 - - - -3.0503 - 2.956 0.592 - 823.8 1 2 1 -0.0048 13 0 0 0 4.91E+07 3.40E+07 - - - 8.0775 0.9989 221125_WJC_METTL3_EV_vs_WT_F08.10012.10012.4 0.000434 Oct-72 R.FREDHPDLIQNAK.K "sp|P17480|UBF1_HUMAN,tr|E9PKP7|E9PKP7_HUMAN" 2 1581.79 1.37 114705 10012 4 1581.793869 396.4548 Nucleolar transcription factor 1 OS=Homo sapiens OX=9606 GN=UBTF PE=1 SV=1 5.38 2050.4 - 324696 - - - 2.4744 - 1.848 0.412 - 79.5 1 2 1 0.0039 13 0 0 0 2.07E+07 1.52E+07 - - - 3.0387 0.9999 221125_WJC_METTL3_EV_vs_WT_F08.10014.10014.2 9.10E-06 Sep-34 K.IGQQPQQPGAPPQQDYTK.A "sp|Q92945|FUBP2_HUMAN,tr|M0R0C6|M0R0C6_HUMAN,tr|M0QYG1|M0QYG1_HUMAN,tr|A0A087WTP3|A0A087WTP3_HUMAN" 4 1979.9701 1.29 114707 10014 2 1979.971128 990.9923 Far upstream element-binding protein 2 OS=Homo sapiens OX=9606 GN=KHSRP PE=1 SV=4 5.83 2050.6 - 191670 - - - 0.5172 - 1.999 0.535 - 144.2 1 2 0 0.001 18 0 0 0 9.23E+06 7.18E+06 - - - 4.6951 0.995 221125_WJC_METTL3_EV_vs_WT_F08.10024.10024.3 0.0526 Aug-36 R.KVELPVPTHR.R "sp|Q9BYD3|RM04_HUMAN,tr|X6RAY8|X6RAY8_HUMAN,tr|K7ES61|K7ES61_HUMAN,tr|K7ELF1|K7ELF1_HUMAN,tr|K7ELQ0|K7ELQ0_HUMAN,tr|K7EKI4|K7EKI4_HUMAN" 6 1174.6822 1.32 114715 10024 3 1174.684146 392.568 "39S ribosomal protein L4, mitochondrial OS=Homo sapiens OX=9606 GN=MRPL4 PE=1 SV=1" 8.75 2051.8 - 273945 - - - 1.6209 - 1.479 0.254 - 111.6 1 2 0 0.0019 10 0 0 0 1.05E+07 7.89E+06 - - - 2.5143 0.9999 221125_WJC_METTL3_EV_vs_WT_F08.10029.10029.3 3.72E-07 13/48 K.KFTNAVTLQQHVR.M "sp|Q9Y467|SALL2_HUMAN,tr|F5H433|F5H433_HUMAN,tr|E7EW59|E7EW59_HUMAN,tr|H0YFS7|H0YFS7_HUMAN" 4 1540.8474 1.32 114718 10029 3 1540.852016 514.6231 Sal-like protein 2 OS=Homo sapiens OX=9606 GN=SALL2 PE=1 SV=4 11 2052.5 - 330478 - - - 2.9893 - 2.836 0.447 - 283.3 1 2 0 0.0046 13 0 0 0 5.64E+06 4.26E+06 - - - 6.3486 0.9934 221125_WJC_METTL3_EV_vs_WT_F08.10031.10031.4 0.00103 Nov-72 R.FR[166.11]EDHPDLIQNAK[136.11].K "sp|P17480|UBF1_HUMAN,tr|E9PKP7|E9PKP7_HUMAN" 2 1599.8124 1.37 114720 10031 4 1599.815595 400.9604 Nucleolar transcription factor 1 OS=Homo sapiens OX=9606 GN=UBTF PE=1 SV=1 5.38 2052.7 - 1.33E+06 - - - 1.9815 - 1.694 0.299 - 61 1 2 1 0.0032 13 0 0 0 2.07E+07 1.52E+07 - - - 2.023 0.9999 221125_WJC_METTL3_EV_vs_WT_F08.10034.10034.2 5.68E-07 Sep-36 K.AGEAPTENPAPPTQQSSAE.- sp|P16989|YBOX3_HUMAN 1 1880.8388 - 114723 10034 2 1880.840433 941.4267 Y-box-binding protein 3 OS=Homo sapiens OX=9606 GN=YBX3 PE=1 SV=4 4.04 2053.1 - 167125 - - - 0.8603 - 2.036 0.661 - 102.4 1 2 0 0.0016 19 0 0 0 - - - - - 5.6706 0.9994 221125_WJC_METTL3_EV_vs_WT_F08.10036.10036.3 0.00171 Nov-60 R.SFGTEDR[166.11]PTDR[166.11]PIPPR[166.11].D "sp|Q8ND56|LS14A_HUMAN,tr|I3L4Q1|I3L4Q1_HUMAN,tr|A0A140TA76|A0A140TA76_HUMAN,tr|K7EMZ9|K7EMZ9_HUMAN" 4 1869.9476 1.01 114724 10036 3 1869.950692 624.3231 Protein LSM14 homolog A OS=Homo sapiens OX=9606 GN=LSM14A PE=1 SV=3 5.84 2053.4 - 592489 - - - 1.6696 - 1.771 0.366 - 69.4 1 2 0 0.0031 16 0 0 0 3.80E+07 3.75E+07 - - - 4.0862 0.9999 221125_WJC_METTL3_EV_vs_WT_F08.10041.10041.3 0.00546 Nov-64 R.FGTGQPAPTAPRPPGDK.K sp|Q9Y6J9|TAF6L_HUMAN 1 1692.8584 1 114729 10041 3 1692.859642 565.2934 TAF6-like RNA polymerase II p300\CBP-associated factor-associated factor 65 kDa subunit 6L OS=Homo sapiens OX=9606 GN=TAF6L PE=1 SV=1 8.75 2053.9 - 332012 - - - 0.752 - 2.315 0.376 - 101.3 1 2 0 0.0013 17 0 0 0 7.44E+06 7.40E+06 - - - 4.8523 0.9997 221125_WJC_METTL3_EV_vs_WT_F08.10042.10042.4 0.000153 Dec-72 K.KFTNAVTLQQHVR.M "sp|Q9Y467|SALL2_HUMAN,tr|F5H433|F5H433_HUMAN,tr|E7EW59|E7EW59_HUMAN,tr|H0YFS7|H0YFS7_HUMAN" 4 1540.8474 1.41 114730 10042 4 1540.852151 386.2191 Sal-like protein 2 OS=Homo sapiens OX=9606 GN=SALL2 PE=1 SV=4 11 2054.1 - 277883 - - - 3.0769 - 2.116 0.433 - 125.2 1 2 0 0.0047 13 0 0 0 3.32E+06 2.35E+06 - - - 3.2714 1 221125_WJC_METTL3_EV_vs_WT_F08.10047.10047.3 7.11E-08 13/40 R.KEMEQLVLDKK.Q sp|Q96A49|SYAP1_HUMAN 1 1359.7432 1.27 114733 10047 3 1359.746099 454.255 Synapse-associated protein 1 OS=Homo sapiens OX=9606 GN=SYAP1 PE=1 SV=1 6.18 2054.6 - 5.98E+06 - - - 2.1416 - 2.594 0.569 - 349.8 1 2 0 0.0029 11 0 0 0 1.21E+08 9.46E+07 - - - 7.5909 1 221125_WJC_METTL3_EV_vs_WT_F08.10048.10048.3 1.34E-07 16/56 K.LITQTFSHHNQLAQK.T "sp|Q9Y266|NUDC_HUMAN,tr|A0A0A0MSS4|A0A0A0MSS4_HUMAN,tr|A0A0A0MSU9|A0A0A0MSU9_HUMAN" 3 1764.9271 1.61 114734 10048 3 1764.931318 589.3163 Nuclear migration protein nudC OS=Homo sapiens OX=9606 GN=NUDC PE=1 SV=1 8.76 2054.7 - 1.17E+06 - - - 2.3803 - 3.517 0.531 - 252.3 1 2 0 0.0042 15 0 0 0 3.77E+08 2.34E+08 - - - 7.7405 0.9998 221125_WJC_METTL3_EV_vs_WT_F08.10050.10050.4 7.11E-05 13/84 K.LTGVFAPRPSTGPHK.L "sp|P62701|RS4X_HUMAN,sp|P22090|RS4Y1_HUMAN,sp|Q8TD47|RS4Y2_HUMAN,tr|C9JEH7|C9JEH7_HUMAN" 4 1563.8522 0.96 114736 10050 4 1563.854469 391.9703 "40S ribosomal protein S4, X isoform OS=Homo sapiens OX=9606 GN=RPS4X PE=1 SV=2" 11 2054.9 - 685414 - - - 1.4758 - 2.53 0.399 - 119.5 1 2 0 0.0023 15 0 0 0 2.93E+07 3.06E+07 - - - 3.0304 0.9981 221125_WJC_METTL3_EV_vs_WT_F08.10051.10051.3 0.000625 19/32 K.KQHLEIELK.Q sp|P15924|DESP_HUMAN 1 1136.6554 0.22 114737 10051 3 1137.660758 379.8924 Desmoplakin OS=Homo sapiens OX=9606 GN=DSP PE=1 SV=3 6.76 2055 - 670923 - - - 884.524 - 3.165 0.401 - 506.4 1 2 0 1.0054 9 0 0 0 1.37E+06 6.35E+06 - - - 6.2046 0.9854 221125_WJC_METTL3_EV_vs_WT_F08.10052.10052.3 0.282 Aug-40 R.KAEEVQAWAQR.K sp|Q9BYN8|RT26_HUMAN 1 1314.668 0.48 114738 10052 3 1314.670445 439.23 "28S ribosomal protein S26, mitochondrial OS=Homo sapiens OX=9606 GN=MRPS26 PE=1 SV=1" 6.14 2055.1 - 396892 - - - 1.8233 - 1.446 0.208 - 101.7 1 2 0 0.0024 11 0 0 0 3.48E+06 7.25E+06 - - - 1.906 0.9994 221125_WJC_METTL3_EV_vs_WT_F08.10053.10053.3 0.000137 16/52 R.LQEAQLYKEEGNQR.Y "sp|Q8N5M4|TTC9C_HUMAN,tr|E9PKV8|E9PKV8_HUMAN,tr|E7EST3|E7EST3_HUMAN" 3 1704.8431 1.05 114739 10053 3 1704.849127 569.2883 Tetratricopeptide repeat protein 9C OS=Homo sapiens OX=9606 GN=TTC9C PE=1 SV=1 4.79 2055.2 - 348016 - - - 3.5282 - 3.256 0.474 - 345.3 1 2 1 0.006 14 0 0 0 1.34E+07 1.29E+07 - - - 6.9602 1 221125_WJC_METTL3_EV_vs_WT_F08.10060.10060.3 9.76E-09 16/76 R.GDNQAGGAAAAAAAPEPPPR.S "sp|O14654|IRS4_HUMAN,tr|A0A804CF45|A0A804CF45_HUMAN" 2 1787.8551 1.36 114744 10060 3 1787.858225 596.959 Insulin receptor substrate 4 OS=Homo sapiens OX=9606 GN=IRS4 PE=1 SV=1 4.37 2056.1 - 533474 - - - 1.7624 - 2.903 0.542 - 190.2 1 2 0 0.0032 20 0 0 0 9.29E+07 6.83E+07 - - - 7.1674 1 221125_WJC_METTL3_EV_vs_WT_F08.10061.10061.3 2.46E-08 18/76 K.TPPPRPSPLEAGSDGC[160.03]EEPK.Q sp|Q9BUA3|SPNDC_HUMAN 1 2119.9844 2.82 114745 10061 3 2119.985363 707.6688 Spindlin interactor and repressor of chromatin-binding protein OS=Homo sapiens OX=9606 GN=SPINDOC PE=1 SV=3 4.41 2056.2 - 509030 - - - 0.4382 - 2.931 0.542 - 281.1 1 2 0 0.0009 20 0 0 0 9.48E+07 3.36E+07 - - - 7.1913 0.9926 221125_WJC_METTL3_EV_vs_WT_F08.10063.10063.3 0.0632 Oct-56 K.NTESSAFGGSLPAK[136.11]K[136.11].S "sp|Q7Z4H7|HAUS6_HUMAN,tr|Q5VY60|Q5VY60_HUMAN,tr|Q5SYF9|Q5SYF9_HUMAN" 3 1508.7806 0.53 114747 10063 3 1508.782131 503.9341 HAUS augmin-like complex subunit 6 OS=Homo sapiens OX=9606 GN=HAUS6 PE=1 SV=2 8.59 2056.5 - 328803 - - - 1.0333 - 1.433 0.232 - 61.5 1 2 0 0.0016 15 0 0 0 2.41E+06 4.54E+06 - - - 2.0649 1 221125_WJC_METTL3_EV_vs_WT_F08.10065.10065.2 4.94E-06 17/20 R.K[136.11]EMEQLVLDK[136.11]K[136.11].Q sp|Q96A49|SYAP1_HUMAN 1 1383.7858 1.3 114749 10065 2 1383.789914 692.9002 Synapse-associated protein 1 OS=Homo sapiens OX=9606 GN=SYAP1 PE=1 SV=1 6.18 2056.8 - 249149 - - - 2.9824 - 2.843 0.558 - 963.8 1 2 0 0.0041 11 0 0 0 4.41E+06 3.40E+06 - - - 5.9877 1 221125_WJC_METTL3_EV_vs_WT_F08.10069.10069.4 3.97E-05 15/84 K.LITQTFSHHNQLAQK.T "sp|Q9Y266|NUDC_HUMAN,tr|A0A0A0MSS4|A0A0A0MSS4_HUMAN,tr|A0A0A0MSU9|A0A0A0MSU9_HUMAN" 3 1764.9271 1.38 114751 10069 4 1764.930606 442.2391 Nuclear migration protein nudC OS=Homo sapiens OX=9606 GN=NUDC PE=1 SV=1 8.76 2057.3 - 9.33E+06 - - - 1.9769 - 2.924 0.579 - 175.4 1 2 0 0.0035 15 0 0 0 3.51E+08 2.54E+08 - - - 4.6486 0.9987 221125_WJC_METTL3_EV_vs_WT_F08.10070.10070.4 0.0019 14/84 K.LTGVFAPR[166.11]PSTGPHK[136.11].L "sp|P62701|RS4X_HUMAN,sp|P22090|RS4Y1_HUMAN,sp|Q8TD47|RS4Y2_HUMAN,tr|C9JEH7|C9JEH7_HUMAN" 4 1581.8746 0.96 114752 10070 4 1581.876891 396.4759 "40S ribosomal protein S4, X isoform OS=Homo sapiens OX=9606 GN=RPS4X PE=1 SV=2" 11 2057.3 - 2.12E+06 - - - 1.4287 - 2.151 0.286 - 102.2 1 2 0 0.0023 15 0 0 0 2.93E+07 3.06E+07 - - - 1.9888 0.9998 221125_WJC_METTL3_EV_vs_WT_F08.10071.10071.3 0.000228 14/36 R.LKDIDEDFKR.E "sp|Q8NHH9|ATLA2_HUMAN,tr|B5MCN0|B5MCN0_HUMAN,tr|H7C3A2|H7C3A2_HUMAN,tr|C9JQQ5|C9JQQ5_HUMAN" 4 1277.6616 1.23 114753 10071 3 1277.662479 426.8945 Atlastin-2 OS=Homo sapiens OX=9606 GN=ATL2 PE=1 SV=2 4.68 2057.5 - 431654 - - - 0.7146 - 2.442 0.462 - 262 1 2 1 0.0009 10 0 0 0 4.76E+06 3.87E+06 - - - 6.298 0.9863 221125_WJC_METTL3_EV_vs_WT_F08.10074.10074.2 0.000635 20-Dec Q.TFSHHNQLAQK.T "sp|Q9Y266|NUDC_HUMAN,tr|A0A0A0MSS4|A0A0A0MSS4_HUMAN,tr|A0A0A0MSU9|A0A0A0MSU9_HUMAN" 3 1309.6527 5.5 114756 10074 2 1309.654961 655.8336 Nuclear migration protein nudC OS=Homo sapiens OX=9606 GN=NUDC PE=1 SV=1 8.47 2057.8 - 88490.6 - - - 1.7012 - 2.37 0.474 - 475.2 1 1 0 0.0022 11 0 0 0 1.59E+06 2.89E+05 - - - 4.8756 0.9998 221125_WJC_METTL3_EV_vs_WT_F08.10078.10078.2 0.000148 16-Sep K.VTMQNLNDR.L "sp|P13645|K1C10_HUMAN,sp|Q7Z3Z0|K1C25_HUMAN,sp|Q7Z3Y9|K1C26_HUMAN,sp|P02533|K1C14_HUMAN,sp|Q7Z3Y8|K1C27_HUMAN,sp|P08779|K1C16_HUMAN,sp|Q7Z3Y7|K1C28_HUMAN,tr|A0A1B0GVI3|A0A1B0GVI3_HUMAN" 8 1089.5237 999 114758 10078 2 1089.524692 545.7691 "Keratin, type I cytoskeletal 10 OS=Homo sapiens OX=9606 GN=KRT10 PE=1 SV=6" 5.81 2058.4 - 1.13E+06 - - - 0.9178 - 1.941 0.439 - 499 1 2 0 0.001 9 0 0 0 1.19E+07 0.00E+00 - - - 4.2018 0.9999 221125_WJC_METTL3_EV_vs_WT_F08.10079.10079.3 5.31E-05 18/52 R.LQEAQLYK[136.11]EEGNQR[166.11].Y "sp|Q8N5M4|TTC9C_HUMAN,tr|E9PKV8|E9PKV8_HUMAN,tr|E7EST3|E7EST3_HUMAN" 3 1722.8656 1.19 114759 10079 3 1722.866901 575.2958 Tetratricopeptide repeat protein 9C OS=Homo sapiens OX=9606 GN=TTC9C PE=1 SV=1 4.79 2058.4 - 1.05E+06 - - - 0.7656 - 3.268 0.473 - 668 1 2 1 0.0013 14 0 0 0 1.29E+07 1.08E+07 - - - 6.9601 1 221125_WJC_METTL3_EV_vs_WT_F08.10080.10080.2 1.54E-09 18/28 K.SSQGDSGVDLSAESR.E "sp|Q5JSZ5|PRC2B_HUMAN,tr|A0A804HKC3|A0A804HKC3_HUMAN,tr|A0A804HJR4|A0A804HJR4_HUMAN" 3 1493.6594 1.89 114760 10080 2 1493.659594 747.837 Protein PRRC2B OS=Homo sapiens OX=9606 GN=PRRC2B PE=1 SV=2 4.03 2058.6 - 850627 - - - 0.1339 - 3.445 0.626 - 1379.8 1 2 0 0.0002 15 0 0 0 6.54E+07 3.45E+07 - - - 6.7056 0.9999 221125_WJC_METTL3_EV_vs_WT_F08.10082.10082.3 0.000464 16/40 R.RQPEAVHLLDK.L sp|Q92621|NU205_HUMAN 1 1304.7201 1.44 114762 10082 3 1304.719537 435.914 Nuclear pore complex protein Nup205 OS=Homo sapiens OX=9606 GN=NUP205 PE=1 SV=3 6.75 2058.8 - 496702 - - - -0.4192 - 2.388 0.413 - 350.6 1 2 0 -0.0005 11 0 0 0 1.12E+07 7.82E+06 - - - 5.6172 0.9982 221125_WJC_METTL3_EV_vs_WT_F08.10083.10083.3 0.0426 Oct-32 K.YK[136.11]PLDLR[166.11]PK[136.11].K sp|P42766|RL35_HUMAN 1 1154.7022 0.001 114763 10083 3 1154.702311 385.908 60S ribosomal protein L35 OS=Homo sapiens OX=9606 GN=RPL35 PE=1 SV=2 9.7 2058.9 - 454104 - - - 0.097 - 2.026 0.2 - 128.5 1 2 0 0.0001 9 0 0 0 0.00E+00 9.70E+06 - - - 2.8977 0.9896 221125_WJC_METTL3_EV_vs_WT_F08.10084.10084.3 6.38E-06 13/56 F.SQPPAPPHQNTFPPR.S sp|Q96I24|FUBP3_HUMAN 1 1669.8325 999 114764 10084 3 1669.835806 557.6181 Far upstream element-binding protein 3 OS=Homo sapiens OX=9606 GN=FUBP3 PE=1 SV=2 9.49 2059.1 - 314795 - - - 1.987 - 2.471 0.445 - 201 1 1 0 0.0033 15 0 0 0 4.80E+06 0.00E+00 - - - 5.8609 0.949 221125_WJC_METTL3_EV_vs_WT_F08.10085.10085.3 0.00326 Oct-52 L.ITQTFSHHNQLAQK.T "sp|Q9Y266|NUDC_HUMAN,tr|A0A0A0MSS4|A0A0A0MSS4_HUMAN,tr|A0A0A0MSU9|A0A0A0MSU9_HUMAN" 3 1651.8431 2.12 114765 10085 3 1651.843714 551.6216 Nuclear migration protein nudC OS=Homo sapiens OX=9606 GN=NUDC PE=1 SV=1 8.76 2059.2 - 300134 - - - 0.4002 - 1.911 0.318 - 111.6 1 1 0 0.0007 14 0 0 0 7.77E+06 3.67E+06 - - - 3.8063 1 221125_WJC_METTL3_EV_vs_WT_F08.10086.10086.2 2.94E-09 16/28 K.LITQTFSHHNQLAQK.T "sp|Q9Y266|NUDC_HUMAN,tr|A0A0A0MSS4|A0A0A0MSS4_HUMAN,tr|A0A0A0MSU9|A0A0A0MSU9_HUMAN" 3 1764.9271 1.62 114766 10086 2 1764.929204 883.4708 Nuclear migration protein nudC OS=Homo sapiens OX=9606 GN=NUDC PE=1 SV=1 8.76 2059.3 - 246736 - - - 1.1825 - 3.514 0.653 - 908.5 1 2 0 0.0021 15 0 0 0 7.97E+06 4.91E+06 - - - 6.9532 0.9997 221125_WJC_METTL3_EV_vs_WT_F08.10087.10087.2 0.00427 28-Sep K.LITQTFSHHNQLAQK[136.11].T "sp|Q9Y266|NUDC_HUMAN,tr|A0A0A0MSS4|A0A0A0MSS4_HUMAN,tr|A0A0A0MSU9|A0A0A0MSU9_HUMAN" 3 1772.9413 1.62 114767 10087 2 1772.944726 887.4779 Nuclear migration protein nudC OS=Homo sapiens OX=9606 GN=NUDC PE=1 SV=1 8.76 2059.4 - 141214 - - - 1.9228 - 2.347 0.477 - 200.1 1 2 0 0.0034 15 0 0 0 7.97E+06 4.91E+06 - - - 4.6605 0.9058 221125_WJC_METTL3_EV_vs_WT_F08.10089.10089.2 0.0002 30-Jul S.SLTLQNSDSSASAPNK.C sp|Q86XN7|PRSR1_HUMAN 1 1618.7798 7.93 114769 10089 2 1618.785337 810.3972 Proline and serine-rich protein 1 OS=Homo sapiens OX=9606 GN=PROSER1 PE=1 SV=2 5.55 2059.7 - 61149.5 - - - 3.3939 - 1.471 0.495 - 129.4 1 1 0 0.0055 16 0 0 0 5.60E+05 7.06E+04 - - - 3.6442 0.9998 221125_WJC_METTL3_EV_vs_WT_F08.10093.10093.4 0.00178 Oct-84 K.LITQTFSHHNQLAQK[136.11].T "sp|Q9Y266|NUDC_HUMAN,tr|A0A0A0MSS4|A0A0A0MSS4_HUMAN,tr|A0A0A0MSU9|A0A0A0MSU9_HUMAN" 3 1772.9413 1.24 114772 10093 4 1772.940145 444.2426 Nuclear migration protein nudC OS=Homo sapiens OX=9606 GN=NUDC PE=1 SV=1 8.76 2060.1 - 1.37E+07 - - - -0.661 - 2.517 0.373 - 59.5 1 2 0 -0.0012 15 0 0 0 3.51E+08 2.84E+08 - - - 2.8026 1 221125_WJC_METTL3_EV_vs_WT_F08.10094.10094.2 6.13E-07 16/28 K.SSQGDSGVDLSAESR[166.11].E "sp|Q5JSZ5|PRC2B_HUMAN,tr|A0A804HKC3|A0A804HKC3_HUMAN,tr|A0A804HJR4|A0A804HJR4_HUMAN" 3 1503.6677 1.89 114773 10094 2 1503.666893 752.8411 Protein PRRC2B OS=Homo sapiens OX=9606 GN=PRRC2B PE=1 SV=2 4.03 2060.2 - 1.27E+06 - - - -0.5127 - 3.437 0.642 - 1132.1 1 2 0 -0.0008 15 0 0 0 6.54E+07 3.45E+07 - - - 6.8179 1 221125_WJC_METTL3_EV_vs_WT_F08.10095.10095.3 0.000258 17/56 K.SEDSSGAAGLSGLHR[166.11].T "sp|Q86U86|PB1_HUMAN,tr|H0Y5B5|H0Y5B5_HUMAN,tr|E7EVG2|E7EVG2_HUMAN" 3 1452.6833 1.8 114774 10095 3 1452.684226 485.235 Protein polybromo-1 OS=Homo sapiens OX=9606 GN=PBRM1 PE=1 SV=1 5.3 2060.3 - 1.03E+06 - - - 0.6691 - 3.341 0.434 - 406.5 1 2 0 0.001 15 0 0 0 4.76E+07 2.64E+07 - - - 6.526 0.9985 221125_WJC_METTL3_EV_vs_WT_F08.10097.10097.3 0.0142 Oct-72 K.AGEAPTENPAPPTQQSSAE.- sp|P16989|YBOX3_HUMAN 1 1880.8388 - 114776 10097 3 1880.833245 627.9535 Y-box-binding protein 3 OS=Homo sapiens OX=9606 GN=YBX3 PE=1 SV=4 4.04 2060.5 - 987592 - - - -2.9614 - 2.029 0.332 - 117.7 1 2 0 -0.0056 19 0 0 0 - - - - - 3.9782 1 221125_WJC_METTL3_EV_vs_WT_F08.10099.10099.3 8.19E-05 19/60 R.TGSISSSVSVPAKPER.R "sp|Q6PJT7|ZC3HE_HUMAN,tr|G3V256|G3V256_HUMAN,tr|H0YJ87|H0YJ87_HUMAN,tr|G3V5I6|G3V5I6_HUMAN,tr|H0YJA2|H0YJA2_HUMAN" 5 1600.842 1.3 114778 10099 3 1600.845334 534.6213 Zinc finger CCCH domain-containing protein 14 OS=Homo sapiens OX=9606 GN=ZC3H14 PE=1 SV=1 8.41 2060.6 - 866711 - - - 2.0514 - 3.83 0.515 - 429.1 1 2 0 0.0033 16 0 0 0 4.61E+07 3.55E+07 - - - 7.7264 0.9926 221125_WJC_METTL3_EV_vs_WT_F08.10100.10100.3 0.00979 Sep-44 K.LDLR[166.11]DDK[136.11]DTIEK[136.11].L "sp|P63000|RAC1_HUMAN,sp|P15153|RAC2_HUMAN,tr|B1AH77|B1AH77_HUMAN,tr|B1AH78|B1AH78_HUMAN,tr|B1AH80|B1AH80_HUMAN" 5 1485.7885 2.88 114779 10100 3 1485.790054 496.2701 Ras-related C3 botulinum toxin substrate 1 OS=Homo sapiens OX=9606 GN=RAC1 PE=1 SV=1 4.36 2060.7 - 750337 - - - 1.0405 - 2.007 0.232 - 103.7 1 2 2 0.0015 12 0 0 0 5.19E+07 1.81E+07 - - - 3.0571 0.9999 221125_WJC_METTL3_EV_vs_WT_F08.10102.10102.3 2.44E-09 14/64 K.ITDSAGHILYSKEDATK.G "sp|P49755|TMEDA_HUMAN,tr|G3V2K7|G3V2K7_HUMAN" 2 1847.9265 1.4 114781 10102 3 1847.927342 616.9828 Transmembrane emp24 domain-containing protein 10 OS=Homo sapiens OX=9606 GN=TMED10 PE=1 SV=2 5.38 2061 - 637140 - - - 0.4513 - 3.378 0.581 - 279.2 1 2 1 0.0008 17 0 0 0 4.40E+06 3.13E+06 - - - 8.0926 0.9932 221125_WJC_METTL3_EV_vs_WT_F08.10106.10106.2 0.000703 13/24 L.TQTFSHHNQLAQK.T "sp|Q9Y266|NUDC_HUMAN,tr|A0A0A0MSS4|A0A0A0MSS4_HUMAN,tr|A0A0A0MSU9|A0A0A0MSU9_HUMAN" 3 1538.759 2.22 114785 10106 2 1538.760011 770.3868 Nuclear migration protein nudC OS=Homo sapiens OX=9606 GN=NUDC PE=1 SV=1 8.47 2061.5 - 177840 - - - 0.6642 - 2.869 0.475 - 548.7 1 1 0 0.001 13 0 0 0 2.66E+06 1.20E+06 - - - 5.2541 1 221125_WJC_METTL3_EV_vs_WT_F08.10110.10110.3 2.77E-06 15/60 R.TGSISSSVSVPAK[136.11]PER[166.11].R "sp|Q6PJT7|ZC3HE_HUMAN,tr|G3V256|G3V256_HUMAN,tr|H0YJ87|H0YJ87_HUMAN,tr|G3V5I6|G3V5I6_HUMAN,tr|H0YJA2|H0YJA2_HUMAN" 5 1618.8645 1.3 114787 10110 3 1618.865868 540.6288 Zinc finger CCCH domain-containing protein 14 OS=Homo sapiens OX=9606 GN=ZC3H14 PE=1 SV=1 8.41 2062 - 1.49E+06 - - - 0.8327 - 3.288 0.533 - 260 1 2 0 0.0013 16 0 0 0 4.61E+07 3.54E+07 - - - 7.5361 0.9994 221125_WJC_METTL3_EV_vs_WT_F08.10111.10111.3 0.00815 13/44 K.LDLRDDKDTIEK.L "sp|P63000|RAC1_HUMAN,sp|P15153|RAC2_HUMAN,tr|B1AH77|B1AH77_HUMAN,tr|B1AH78|B1AH78_HUMAN,tr|B1AH80|B1AH80_HUMAN" 5 1459.7518 11.06 114788 10111 3 1459.752708 487.5912 Ras-related C3 botulinum toxin substrate 1 OS=Homo sapiens OX=9606 GN=RAC1 PE=1 SV=1 4.36 2062.1 - 970315 - - - 0.596 - 2.63 0.335 - 273.7 1 2 2 0.0009 12 0 0 0 2.43E+08 2.20E+07 - - - 4.955 0.9993 221125_WJC_METTL3_EV_vs_WT_F08.10112.10112.3 0.00153 Oct-36 R.K[136.11]VELPVPTHR[166.11].R "sp|Q9BYD3|RM04_HUMAN,tr|X6RAY8|X6RAY8_HUMAN,tr|K7ES61|K7ES61_HUMAN,tr|K7ELF1|K7ELF1_HUMAN,tr|K7ELQ0|K7ELQ0_HUMAN,tr|K7EKI4|K7EKI4_HUMAN" 6 1192.7047 1.39 114789 10112 3 1192.704751 398.5755 "39S ribosomal protein L4, mitochondrial OS=Homo sapiens OX=9606 GN=MRPL4 PE=1 SV=1" 8.75 2062.2 - 477562 - - - 0.0327 - 1.633 0.323 - 194.4 1 2 0 0 10 0 0 0 1.64E+07 1.18E+07 - - - 3.5734 0.9984 221125_WJC_METTL3_EV_vs_WT_F08.10113.10113.3 0.000177 Nov-52 R.KNFQLEEEEQNEAK.L "sp|Q9Y5A7|NUB1_HUMAN,tr|H3BM74|H3BM74_HUMAN,tr|C9JRT6|C9JRT6_HUMAN,tr|H3BM14|H3BM14_HUMAN,tr|F8WDB6|F8WDB6_HUMAN" 5 1734.8061 1.34 114790 10113 3 1734.805649 579.276 NEDD8 ultimate buster 1 OS=Homo sapiens OX=9606 GN=NUB1 PE=1 SV=2 4.33 2062.3 - 300168 - - - -0.2358 - 2.111 0.219 - 170.6 1 2 0 -0.0004 14 0 0 0 4.08E+06 3.03E+06 - - - 2.9671 0.9942 221125_WJC_METTL3_EV_vs_WT_F08.10114.10114.2 7.17E-06 26-Oct Y.TSQNNAQGPLYEQR.S "sp|Q14157|UBP2L_HUMAN,tr|F8W726|F8W726_HUMAN" 2 1604.7543 2.96 114791 10114 2 1604.754899 803.3844 Ubiquitin-associated protein 2-like OS=Homo sapiens OX=9606 GN=UBAP2L PE=1 SV=2 5.66 2062.5 - 298187 - - - 0.3751 - 2.455 0.558 - 244.7 1 1 0 0.0006 14 0 0 0 1.45E+07 4.89E+06 - - - 5.416 0.9929 221125_WJC_METTL3_EV_vs_WT_F08.10116.10116.2 3.69E-07 26-Nov Y.TSQNNAQGPLYEQR[166.11].S "sp|Q14157|UBP2L_HUMAN,tr|F8W726|F8W726_HUMAN" 2 1614.7626 2.96 114793 10116 2 1614.760682 808.3886 Ubiquitin-associated protein 2-like OS=Homo sapiens OX=9606 GN=UBAP2L PE=1 SV=2 5.66 2062.7 - 124383 - - - -1.1674 - 2.428 0.559 - 425 1 1 0 -0.0019 14 0 0 0 1.45E+07 4.89E+06 - - - 5.3952 1 221125_WJC_METTL3_EV_vs_WT_F08.10120.10120.3 5.31E-07 13/60 R.DGQVINETSQHHDDLE.- sp|P08670|VIME_HUMAN 1 1835.7922 - 114795 10120 3 1835.794297 612.938 Vimentin OS=Homo sapiens OX=9606 GN=VIM PE=1 SV=4 4.28 2063.2 - 602623 - - - 1.1428 - 2.739 0.551 - 258.6 1 2 0 0.0021 16 0 0 0 - - - - - 7.2679 0.7866 221125_WJC_METTL3_EV_vs_WT_F08.10121.10121.4 0.0147 Nov-96 L.FVTGVHEEATEEDIHDK.F "sp|Q9Y5S9|RBM8A_HUMAN,tr|A0A0J9YW13|A0A0J9YW13_HUMAN" 2 1954.8909 1.58 114796 10121 4 1954.893171 489.73 RNA-binding protein 8A OS=Homo sapiens OX=9606 GN=RBM8A PE=1 SV=1 4.35 2063.3 - 392973 - - - 1.1868 - 1.763 0.264 - 79.6 1 1 0 0.0023 17 0 0 0 2.82E+06 1.79E+06 - - - 1.7201 0.9781 221125_WJC_METTL3_EV_vs_WT_F08.10125.10125.4 4.21E-06 18/126 F.ASSLVSGLNSSASEPAK[136.11]EPAK[136.11]K[136.11].S "sp|Q86U44|MTA70_HUMAN,tr|F5H6D8|F5H6D8_HUMAN,tr|H0YFV6|H0YFV6_HUMAN,tr|B4DTN4|B4DTN4_HUMAN" 4 2181.1703 0.54 114800 10125 4 2181.174459 546.2999 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 8.54 2063.7 - 418072 - - - 1.8944 - 3.28 0.503 - 125.6 1 1 1 0.0041 22 0 0 0 1.16E+07 2.14E+07 - - - 3.9916 0.9508 221125_WJC_METTL3_EV_vs_WT_F08.10128.10128.2 0.684 Apr-32 R.STPGVASTPQTPVSSSR[166.11].A tr|A0A1W2PQ72|A0A1W2PQ72_HUMAN 1 1667.8354 1.89 114803 10128 2 1667.839701 834.925 Myb_DNA-bind_4 domain-containing protein OS=Homo sapiens OX=9606 GN=LOC100421372 PE=1 SV=1 9.47 2064.1 - 119622 - - - 2.58 - 0.955 0.193 - 42 1 2 0 0.0043 17 0 0 0 3.90E+06 2.06E+06 - - - 0.3519 1 221125_WJC_METTL3_EV_vs_WT_F08.10130.10130.2 1.56E-05 14/24 K.NEEENENSISQYK.E sp|P82673|RT35_HUMAN 1 1582.6747 1.54 114805 10130 2 1582.67435 792.3446 "28S ribosomal protein S35, mitochondrial OS=Homo sapiens OX=9606 GN=MRPS35 PE=1 SV=1" 4.09 2064.3 - 107825 - - - -0.2275 - 2.941 0.653 - 771.5 1 2 0 -0.0004 13 0 0 0 4.92E+06 3.20E+06 - - - 6.6326 1 221125_WJC_METTL3_EV_vs_WT_F08.10132.10132.3 1.97E-09 15/56 K.SEDSSGAAGLSGLHR.T "sp|Q86U86|PB1_HUMAN,tr|H0Y5B5|H0Y5B5_HUMAN,tr|E7EVG2|E7EVG2_HUMAN" 3 1442.675 1.81 114806 10132 3 1442.676781 481.8989 Protein polybromo-1 OS=Homo sapiens OX=9606 GN=PBRM1 PE=1 SV=1 5.3 2064.6 - 4.59E+06 - - - 1.2456 - 3.064 0.609 - 261.8 1 2 0 0.0018 15 0 0 0 4.77E+07 2.64E+07 - - - 8.251 1 221125_WJC_METTL3_EV_vs_WT_F08.10134.10134.3 2.14E-10 15/48 K.RTAAENDFVTLKK.D sp|P35908|K22E_HUMAN 1 1491.8045 291.72 114807 10134 3 1491.807875 498.2755 "Keratin, type II cytoskeletal 2 epidermal OS=Homo sapiens OX=9606 GN=KRT2 PE=1 SV=2" 8.59 2064.8 - 1.34E+06 - - - 2.2342 - 2.884 0.565 - 351.6 1 2 0 0.0033 13 0 0 0 1.46E+07 5.02E+04 - - - 7.71 1 221125_WJC_METTL3_EV_vs_WT_F08.10135.10135.3 2.15E-06 18/64 K.ALGGDVSDQSLESHSQK.V sp|Q9UKJ3|GPTC8_HUMAN 1 1756.8228 1.16 114808 10135 3 1756.823909 586.6149 G patch domain-containing protein 8 OS=Homo sapiens OX=9606 GN=GPATCH8 PE=1 SV=2 4.54 2064.9 - 595102 - - - 0.6478 - 2.888 0.547 - 304.4 1 2 0 0.0011 17 0 0 0 2.12E+07 1.82E+07 - - - 7.3175 0.9993 221125_WJC_METTL3_EV_vs_WT_F08.10137.10137.3 0.0341 Dec-32 K.NIHLNLDR[166.11]R[166.11].T "sp|Q9Y5S9|RBM8A_HUMAN,tr|A0A0J9YW13|A0A0J9YW13_HUMAN" 2 1169.6532 1.53 114810 10137 3 1169.654032 390.8917 RNA-binding protein 8A OS=Homo sapiens OX=9606 GN=RBM8A PE=1 SV=1 9.61 2065 - 1.31E+06 - - - 0.6865 - 1.88 0.281 - 275.7 1 2 0 0.0008 9 0 0 0 5.68E+07 3.71E+07 - - - 3.5752 0.9848 221125_WJC_METTL3_EV_vs_WT_F08.10138.10138.3 0.0501 Nov-48 R.GGNRFEPYANPTK.R "sp|P52272|HNRPM_HUMAN,tr|M0R019|M0R019_HUMAN,tr|M0R0Y6|M0R0Y6_HUMAN,tr|M0R0N3|M0R0N3_HUMAN,tr|A0A087X0X3|A0A087X0X3_HUMAN,tr|M0QYQ7|M0QYQ7_HUMAN,tr|M0R2T0|M0R2T0_HUMAN" 7 1449.7001 2.37 114811 10138 3 1449.698905 484.2406 Heterogeneous nuclear ribonucleoprotein M OS=Homo sapiens OX=9606 GN=HNRNPM PE=1 SV=3 8.59 2065.1 - 2.41E+06 - - - -0.8084 - 1.62 0.237 - 128.9 1 2 1 -0.0012 13 0 0 0 1.68E+07 7.07E+06 - - - 2.49 0.9998 221125_WJC_METTL3_EV_vs_WT_F08.10139.10139.2 4.32E-06 13/26 R.SLLEGEGSSGGGGR.G "sp|P13645|K1C10_HUMAN,tr|A0A1B0GVI3|A0A1B0GVI3_HUMAN" 2 1261.5899 999 114812 10139 2 1261.592153 631.8022 "Keratin, type I cytoskeletal 10 OS=Homo sapiens OX=9606 GN=KRT10 PE=1 SV=6" 4.53 2065.2 - 378506 - - - 1.8191 - 2.469 0.584 - 594 1 2 0 0.0023 14 0 0 0 6.86E+06 0.00E+00 - - - 5.6218 0.9999 221125_WJC_METTL3_EV_vs_WT_F08.10140.10140.3 2.81E-07 13/56 R.QAVTNPNNTFYATK[136.11]R[166.11].L "sp|P38646|GRP75_HUMAN,tr|H0Y8K0|H0Y8K0_HUMAN,tr|A0A7I2V2S7|A0A7I2V2S7_HUMAN,tr|A0A7I2V2G2|A0A7I2V2G2_HUMAN,tr|A0A3B3ITI4|A0A3B3ITI4_HUMAN,tr|A0A7I2V3F7|A0A7I2V3F7_HUMAN,tr|A0A7I2YQB2|A0A7I2YQB2_HUMAN,tr|D6RCD7|D6RCD7_HUMAN" 8 1741.8867 0.58 114813 10140 3 1741.887849 581.6362 "Stress-70 protein, mitochondrial OS=Homo sapiens OX=9606 GN=HSPA9 PE=1 SV=2" 9.99 2065.4 - 363293 - - - 0.6872 - 2.487 0.356 - 258.1 1 2 0 0.0012 15 0 0 0 2.14E+07 3.72E+07 - - - 4.8861 0.9999 221125_WJC_METTL3_EV_vs_WT_F08.10147.10147.2 0.0111 24-Nov K.NEEENENSISQYK[136.11].E sp|P82673|RT35_HUMAN 1 1590.6889 1.54 114818 10147 2 1590.688168 796.3517 "28S ribosomal protein S35, mitochondrial OS=Homo sapiens OX=9606 GN=MRPS35 PE=1 SV=1" 4.09 2066.3 - 235462 - - - -0.4665 - 2.524 0.513 - 428.4 1 2 0 -0.0007 13 0 0 0 4.92E+06 3.20E+06 - - - 5.206 0.9998 221125_WJC_METTL3_EV_vs_WT_F08.10155.10155.2 0.000507 20-Nov R.VEIIANDQGNR[166.11].L "sp|P11021|BIP_HUMAN,sp|P48741|HSP77_HUMAN,sp|P54652|HSP72_HUMAN,sp|P0DMV8|HS71A_HUMAN,sp|P34931|HS71L_HUMAN,sp|P11142|HSP7C_HUMAN,sp|P0DMV9|HS71B_HUMAN,sp|P17066|HSP76_HUMAN,tr|E9PQQ4|E9PQQ4_HUMAN,tr|E9PNE6|E9PNE6_HUMAN,tr|E9PKE3|E9PKE3_HUMAN,tr|A0A7P0TB36|A0A7P0TB36_HUMAN,tr|E9PLF4|E9PLF4_HUMAN,tr|A0A7P0TAI0|A0A7P0TAI0_HUMAN,tr|Q53FA3|Q53FA3_HUMAN,tr|E9PI65|E9PI65_HUMAN,tr|E9PK54|E9PK54_HUMAN,tr|E9PN25|E9PN25_HUMAN,tr|E9PPY6|E9PPY6_HUMAN,tr|E9PQK7|E9PQK7_HUMAN,tr|A0A0G2JIW1|A0A0G2JIW1_HUMAN" 21 1237.629 0.13 114824 10155 2 1237.629883 619.8218 Endoplasmic reticulum chaperone BiP OS=Homo sapiens OX=9606 GN=HSPA5 PE=1 SV=2 4.37 2067.3 - 438691 - - - 0.686 - 2.197 0.479 - 435.6 1 2 0 0.0008 11 0 0 0 2.62E+06 2.03E+07 - - - 4.7079 0.9979 221125_WJC_METTL3_EV_vs_WT_F08.10160.10160.3 0.394 Dec-32 K.NIHLNLDRR.T "sp|Q9Y5S9|RBM8A_HUMAN,tr|A0A0J9YW13|A0A0J9YW13_HUMAN" 2 1149.6367 1.53 114828 10160 3 1149.637732 384.2195 RNA-binding protein 8A OS=Homo sapiens OX=9606 GN=RBM8A PE=1 SV=1 9.61 2068 - 4.05E+06 - - - 0.9072 - 1.661 0.248 - 290 1 2 0 0.001 9 0 0 0 5.69E+07 3.71E+07 - - - 2.8339 0.9999 221125_WJC_METTL3_EV_vs_WT_F08.10162.10162.3 1.84E-05 Nov-44 K.KPHIYYGSLEEK.E sp|O43172|PRP4_HUMAN 1 1462.7456 3.26 114829 10162 3 1462.747561 488.5892 U4\U6 small nuclear ribonucleoprotein Prp4 OS=Homo sapiens OX=9606 GN=PRPF4 PE=1 SV=2 6.75 2068.2 - 1.59E+06 - - - 1.3201 - 2.258 0.466 - 132.1 1 2 0 0.0019 12 0 0 0 2.59E+08 7.95E+07 - - - 5.9925 0.9984 221125_WJC_METTL3_EV_vs_WT_F08.10167.10167.3 0.00494 Nov-60 R.TIQRPVTMGDEGGLRR.L "sp|Q14527|HLTF_HUMAN,tr|H7C5K0|H7C5K0_HUMAN,tr|A0A0C4DGA6|A0A0C4DGA6_HUMAN" 3 1784.9316 1.02 114834 10167 3 1784.933595 595.9845 Helicase-like transcription factor OS=Homo sapiens OX=9606 GN=HLTF PE=1 SV=2 9.17 2068.8 - 358408 - - - 1.1457 - 1.691 0.289 - 61.5 1 2 0 0.002 16 0 0 0 1.09E+07 1.06E+07 - - - 3.1094 1 221125_WJC_METTL3_EV_vs_WT_F08.10168.10168.3 4.94E-08 20/76 K.PAASITSK[136.11]PATLTTTSATSK[136.11].L "sp|O43670|ZN207_HUMAN,tr|J3QRS9|J3QRS9_HUMAN,tr|X6R4W8|X6R4W8_HUMAN,tr|J3KS31|J3KS31_HUMAN" 4 1949.0652 0.3 114835 10168 3 1949.063715 650.6957 BUB3-interacting and GLEBS motif-containing protein ZNF207 OS=Homo sapiens OX=9606 GN=ZNF207 PE=1 SV=1 10.02 2068.9 - 278953 - - - -0.7552 - 3.497 0.635 - 265.4 1 1 0 -0.0015 20 0 0 0 4.84E+06 1.61E+07 - - - 8.6564 0.9571 221125_WJC_METTL3_EV_vs_WT_F08.10169.10169.3 0.14 Sep-52 K.QIATLHAQVADMKK.K sp|P35579|MYH9_HUMAN 1 1552.8395 0.75 114836 10169 3 1552.842641 518.6205 Myosin-9 OS=Homo sapiens OX=9606 GN=MYH9 PE=1 SV=4 8.6 2069 - 276607 - - - 1.9925 - 1.351 0.19 - 51.9 2 2 0 0.0031 14 0 0 0 3.94E+06 5.24E+06 - - - 1.3176 0.8663 221125_WJC_METTL3_EV_vs_WT_F08.10170.10170.3 8.25E-08 14/84 F.ASSLVSGLNSSASEPAK[136.11]EPAK[136.11]K[136.11].S "sp|Q86U44|MTA70_HUMAN,tr|F5H6D8|F5H6D8_HUMAN,tr|H0YFV6|H0YFV6_HUMAN,tr|B4DTN4|B4DTN4_HUMAN" 4 2181.1703 0.02 114837 10170 3 2181.165931 728.0641 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 8.54 2069.1 - 269196 - - - -2.0154 - 2.66 0.343 - 177.1 1 1 1 -0.0044 22 0 0 0 8.08E+04 4.20E+06 - - - 4.6823 0.9997 221125_WJC_METTL3_EV_vs_WT_F08.10175.10175.4 0.0011 17/90 R.TIQRPVTMGDEGGLRR.L "sp|Q14527|HLTF_HUMAN,tr|H7C5K0|H7C5K0_HUMAN,tr|A0A0C4DGA6|A0A0C4DGA6_HUMAN" 3 1784.9316 1.1 114840 10175 4 1784.933343 447.2402 Helicase-like transcription factor OS=Homo sapiens OX=9606 GN=HLTF PE=1 SV=2 9.17 2069.8 - 1.53E+06 - - - 1.0045 - 1.954 0.369 - 198.2 1 2 0 0.0018 16 0 0 0 2.52E+07 2.30E+07 - - - 2.6732 1 221125_WJC_METTL3_EV_vs_WT_F08.10176.10176.3 1.26E-07 19/44 K.K[136.11]PHIYYGSLEEK[136.11].E sp|O43172|PRP4_HUMAN 1 1478.774 3.26 114841 10176 3 1478.775201 493.932 U4\U6 small nuclear ribonucleoprotein Prp4 OS=Homo sapiens OX=9606 GN=PRPF4 PE=1 SV=2 6.75 2069.9 - 1.19E+06 - - - 0.7919 - 2.831 0.497 - 373.8 1 2 0 0.0012 12 0 0 0 2.57E+08 7.91E+07 - - - 6.9652 0.9997 221125_WJC_METTL3_EV_vs_WT_F08.10184.10184.3 6.17E-06 Nov-40 R.SESHTDLTFSR[166.11].E sp|O15226|NKRF_HUMAN 1 1288.5923 0.95 114849 10184 3 1288.594259 430.538 NF-kappa-B-repressing factor OS=Homo sapiens OX=9606 GN=NKRF PE=1 SV=2 5.3 2070.8 - 290250 - - - 1.5094 - 2.192 0.346 - 199.7 1 2 0 0.0019 11 0 0 0 3.82E+06 4.02E+06 - - - 4.6265 0.8884 221125_WJC_METTL3_EV_vs_WT_F08.10187.10187.3 0.218 Sep-76 R.GDNQAGGAAAAAAAPEPPPR[166.11].S "sp|O14654|IRS4_HUMAN,tr|A0A804CF45|A0A804CF45_HUMAN" 2 1797.8633 0.26 114851 10187 3 1797.849835 600.2951 Insulin receptor substrate 4 OS=Homo sapiens OX=9606 GN=IRS4 PE=1 SV=1 4.37 2071.2 - 581621 - - - -7.5139 - 1.685 0.291 - 63.2 1 2 0 -0.0135 20 0 0 0 5.28E+06 2.00E+07 - - - 3.0464 0.9987 221125_WJC_METTL3_EV_vs_WT_F08.10189.10189.4 0.0029 Dec-90 R.TIQR[166.11]PVTMGDEGGLR[166.11]R[166.11].L "sp|Q14527|HLTF_HUMAN,tr|H7C5K0|H7C5K0_HUMAN,tr|A0A0C4DGA6|A0A0C4DGA6_HUMAN" 3 1814.9564 1.29 114852 10189 4 1814.957706 454.7464 Helicase-like transcription factor OS=Homo sapiens OX=9606 GN=HLTF PE=1 SV=2 9.17 2071.4 - 1.97E+06 - - - 0.7416 - 1.876 0.285 - 92.5 1 2 0 0.0013 16 0 0 0 2.55E+07 1.99E+07 - - - 1.9279 0.9999 221125_WJC_METTL3_EV_vs_WT_F08.10191.10191.3 5.37E-06 13/56 K.SNPVIPISSSNHSAR[166.11].S sp|O95628|CNOT4_HUMAN 1 1574.804 1.92 114854 10191 3 1574.805511 525.942 CCR4-NOT transcription complex subunit 4 OS=Homo sapiens OX=9606 GN=CNOT4 PE=1 SV=3 9.49 2071.5 - 646756 - - - 0.9354 - 2.419 0.447 - 168.8 1 2 0 0.0015 15 0 0 0 1.41E+08 7.35E+07 - - - 5.8282 0.9998 221125_WJC_METTL3_EV_vs_WT_F08.10196.10196.2 1.57E-06 28-Dec K.SQAPGQPGASQWGSR[166.11].V "sp|Q96EP5|DAZP1_HUMAN,tr|K7EK33|K7EK33_HUMAN,tr|K7EQ55|K7EQ55_HUMAN,tr|K7EQ02|K7EQ02_HUMAN" 4 1522.7152 1.19 114859 10196 2 1522.71716 762.3649 DAZ-associated protein 1 OS=Homo sapiens OX=9606 GN=DAZAP1 PE=1 SV=1 9.47 2072.2 - 260350 - - - 1.2721 - 2.011 0.562 - 251.1 1 2 0 0.0019 15 0 0 0 2.03E+07 1.71E+07 - - - 4.9089 1 221125_WJC_METTL3_EV_vs_WT_F08.10197.10197.2 3.62E-05 13/22 K.KPHIYYGSLEEK.E sp|O43172|PRP4_HUMAN 1 1462.7456 4.78 114860 10197 2 1462.748001 732.3801 U4\U6 small nuclear ribonucleoprotein Prp4 OS=Homo sapiens OX=9606 GN=PRPF4 PE=1 SV=2 6.75 2072.3 - 166503 - - - 1.6209 - 2.947 0.546 - 820.8 1 2 0 0.0024 12 0 0 0 1.02E+07 2.12E+06 - - - 5.9167 1 221125_WJC_METTL3_EV_vs_WT_F08.10207.10207.2 2.82E-07 13/28 K.INNLNVEENSSGDQR.R sp|Q9Y5V3|MAGD1_HUMAN 1 1687.7762 0.92 114867 10207 2 1687.775478 844.8954 Melanoma-associated antigen D1 OS=Homo sapiens OX=9606 GN=MAGED1 PE=1 SV=3 4.14 2073.6 - 148402 - - - -0.4011 - 2.631 0.642 - 604.2 1 2 0 -0.0007 15 0 0 0 4.93E+06 5.37E+06 - - - 6.1609 0.9999 221125_WJC_METTL3_EV_vs_WT_F08.10211.10211.3 4.39E-07 17/56 K.SNPVIPISSSNHSAR.S sp|O95628|CNOT4_HUMAN 1 1564.7958 1.38 114870 10211 3 1564.800839 522.6059 CCR4-NOT transcription complex subunit 4 OS=Homo sapiens OX=9606 GN=CNOT4 PE=1 SV=3 9.49 2074.1 - 4.50E+06 - - - 3.2407 - 2.807 0.552 - 319.4 1 2 0 0.0051 15 0 0 0 1.51E+08 1.09E+08 - - - 7.386 0.9999 221125_WJC_METTL3_EV_vs_WT_F08.10212.10212.3 4.75E-06 Oct-40 R.SESHTDLTFSR.E sp|O15226|NKRF_HUMAN 1 1278.584 0.94 114871 10212 3 1278.586334 427.202 NF-kappa-B-repressing factor OS=Homo sapiens OX=9606 GN=NKRF PE=1 SV=2 5.3 2074.3 - 316401 - - - 1.791 - 1.819 0.477 - 116.1 1 2 0 0.0023 11 0 0 0 3.79E+06 4.02E+06 - - - 5.5571 0.9999 221125_WJC_METTL3_EV_vs_WT_F08.10213.10213.3 8.68E-08 14/56 K.LSDDNTIGKEEIQQR.L "sp|Q13813|SPTN1_HUMAN,tr|A0A0D9SF54|A0A0D9SF54_HUMAN,tr|A0A0D9SGF6|A0A0D9SGF6_HUMAN" 3 1744.8592 1.59 114872 10213 3 1744.861548 582.627 "Spectrin alpha chain, non-erythrocytic 1 OS=Homo sapiens OX=9606 GN=SPTAN1 PE=1 SV=3" 4.32 2074.3 - 2.67E+06 - - - 1.3709 - 3.074 0.559 - 284.3 1 2 1 0.0024 15 0 0 0 6.38E+07 4.01E+07 - - - 7.7019 0.9973 221125_WJC_METTL3_EV_vs_WT_F08.10216.10216.3 0.000462 20/76 K.PAASITSKPATLTTTSATSK.L "sp|O43670|ZN207_HUMAN,tr|J3QRS9|J3QRS9_HUMAN,tr|X6R4W8|X6R4W8_HUMAN,tr|J3KS31|J3KS31_HUMAN" 4 1933.0368 0.3 114875 10216 3 1933.041144 645.3529 BUB3-interacting and GLEBS motif-containing protein ZNF207 OS=Homo sapiens OX=9606 GN=ZNF207 PE=1 SV=1 10.02 2074.6 - 483314 - - - 2.254 - 3.997 0.554 - 453.5 1 1 0 0.0044 20 0 0 0 4.84E+06 1.61E+07 - - - 8.0767 0.9932 221125_WJC_METTL3_EV_vs_WT_F08.10218.10218.2 0.00194 28-Sep K.INNLNVEENSSGDQR[166.11].R sp|Q9Y5V3|MAGD1_HUMAN 1 1697.7844 0.85 114877 10218 2 1698.787996 849.8995 Melanoma-associated antigen D1 OS=Homo sapiens OX=9606 GN=MAGED1 PE=1 SV=3 4.14 2074.9 - 254990 - - - 591.1063 - 2.088 0.517 - 218.8 1 2 0 1.0036 15 0 0 0 4.93E+06 5.84E+06 - - - 4.3544 0.9999 221125_WJC_METTL3_EV_vs_WT_F08.10224.10224.2 9.70E-07 14/22 K.K[136.11]PHIYYGSLEEK[136.11].E sp|O43172|PRP4_HUMAN 1 1478.774 4.78 114881 10224 2 1478.775494 740.3943 U4\U6 small nuclear ribonucleoprotein Prp4 OS=Homo sapiens OX=9606 GN=PRPF4 PE=1 SV=2 6.75 2075.6 - 173075 - - - 0.99 - 2.769 0.512 - 803 1 2 0 0.0015 12 0 0 0 1.02E+07 2.12E+06 - - - 5.502 1 221125_WJC_METTL3_EV_vs_WT_F08.10226.10226.3 5.45E-07 16/56 K.LSDDNTIGK[136.11]EEIQQR[166.11].L "sp|Q13813|SPTN1_HUMAN,tr|A0A0D9SF54|A0A0D9SF54_HUMAN,tr|A0A0D9SGF6|A0A0D9SGF6_HUMAN" 3 1762.8816 1.59 114882 10226 3 1762.883752 588.6345 "Spectrin alpha chain, non-erythrocytic 1 OS=Homo sapiens OX=9606 GN=SPTAN1 PE=1 SV=3" 4.32 2075.9 - 2.98E+06 - - - 1.206 - 3.469 0.62 - 376.5 1 2 1 0.0021 15 0 0 0 6.38E+07 4.01E+07 - - - 8.6975 0.9999 221125_WJC_METTL3_EV_vs_WT_F08.10227.10227.3 0.000398 Dec-44 R.QDQQQLDRPFNR.G sp|Q92576|PHF3_HUMAN 1 1543.7492 0.59 114883 10227 3 1543.751799 515.5903 PHD finger protein 3 OS=Homo sapiens OX=9606 GN=PHF3 PE=1 SV=3 5.96 2075.9 - 841512 - - - 1.7147 - 2.551 0.403 - 313.5 1 2 0 0.0026 12 0 0 0 1.92E+07 3.25E+07 - - - 5.6281 0.9999 221125_WJC_METTL3_EV_vs_WT_F08.10228.10228.3 2.58E-08 14/52 K.SDVNKEYYTQNMER.E "sp|Q9NW64|RBM22_HUMAN,tr|E5RJW4|E5RJW4_HUMAN,tr|E5RHA8|E5RHA8_HUMAN" 3 1775.7785 0.73 114884 10228 3 1775.781688 592.9334 Pre-mRNA-splicing factor RBM22 OS=Homo sapiens OX=9606 GN=RBM22 PE=1 SV=1 4.68 2076.1 - 517257 - - - 1.8161 - 2.598 0.573 - 247.6 1 2 1 0.0032 14 0 0 0 1.63E+07 2.25E+07 - - - 7.4647 0.9799 221125_WJC_METTL3_EV_vs_WT_F08.10230.10230.3 0.261 Sep-48 R.EKQDTFALASQQK.A "sp|P09110|THIK_HUMAN,tr|C9JDE9|C9JDE9_HUMAN,tr|H7C131|H7C131_HUMAN,tr|H0Y4D4|H0Y4D4_HUMAN" 4 1492.7522 1.58 114886 10230 3 1492.752891 498.5913 "3-ketoacyl-CoA thiolase, peroxisomal OS=Homo sapiens OX=9606 GN=ACAA1 PE=1 SV=2" 6.17 2076.3 - 328617 - - - 0.4817 - 1.758 0.201 - 97.5 1 2 1 0.0007 13 0 0 0 2.49E+07 1.57E+07 - - - 2.3104 0.9998 221125_WJC_METTL3_EV_vs_WT_F08.10235.10235.2 4.28E-07 28-Nov K.SNPVIPISSSNHSAR.S sp|O95628|CNOT4_HUMAN 1 1564.7958 1.97 114889 10235 2 1564.796298 783.4052 CCR4-NOT transcription complex subunit 4 OS=Homo sapiens OX=9606 GN=CNOT4 PE=1 SV=3 9.49 2077 - 413321 - - - 0.3387 - 2.079 0.48 - 236.5 1 2 0 0.0005 15 0 0 0 9.46E+06 4.80E+06 - - - 4.3855 0.9994 221125_WJC_METTL3_EV_vs_WT_F08.10236.10236.2 0.000525 28-Jul K.SNPVIPISSSNHSAR[166.11].S sp|O95628|CNOT4_HUMAN 1 1574.804 1.97 114890 10236 2 1574.806283 788.4093 CCR4-NOT transcription complex subunit 4 OS=Homo sapiens OX=9606 GN=CNOT4 PE=1 SV=3 9.49 2077.1 - 206364 - - - 1.4256 - 1.39 0.468 - 104.9 1 2 0 0.0022 15 0 0 0 9.46E+06 4.80E+06 - - - 3.3066 0.9999 221125_WJC_METTL3_EV_vs_WT_F08.10241.10241.3 0.000457 13/40 K.K[136.11]FPFC[160.03]DGAHTK[136.11].H sp|Q9NZ45|CISD1_HUMAN 1 1322.6412 1.3 114893 10241 3 1322.642167 441.8877 CDGSH iron-sulfur domain-containing protein 1 OS=Homo sapiens OX=9606 GN=CISD1 PE=1 SV=1 8.21 2077.8 - 355039 - - - 0.6994 - 1.819 0.427 - 209.6 1 2 0 0.0009 11 0 0 0 1.04E+07 8.06E+06 - - - 5 0.9981 221125_WJC_METTL3_EV_vs_WT_F08.10249.10249.3 0.00142 Dec-68 K.IGQQPQQPGAPPQQDYTK[136.11].A "sp|Q92945|FUBP2_HUMAN,tr|M0R0C6|M0R0C6_HUMAN,tr|M0QYG1|M0QYG1_HUMAN,tr|A0A087WTP3|A0A087WTP3_HUMAN" 4 1987.9843 0.46 114900 10249 3 1987.990516 663.6687 Far upstream element-binding protein 2 OS=Homo sapiens OX=9606 GN=KHSRP PE=1 SV=4 5.83 2078.8 - 541423 - - - 3.1248 - 2.004 0.326 - 157.1 1 2 0 0.0062 18 0 0 0 7.23E+06 1.56E+07 - - - 3.9038 0.9917 221125_WJC_METTL3_EV_vs_WT_F08.10251.10251.4 0.00881 Sep-72 R.LYK[136.11]EELEQTYHAK[136.11].L "sp|P20700|LMNB1_HUMAN,tr|E9PBF6|E9PBF6_HUMAN,tr|A0A0D9SFE5|A0A0D9SFE5_HUMAN" 3 1666.8537 1.43 114901 10251 4 1666.858235 417.7207 Lamin-B1 OS=Homo sapiens OX=9606 GN=LMNB1 PE=1 SV=2 5.5 2079 - 932242 - - - 2.6985 - 1.847 0.308 - 55.1 1 2 1 0.0045 13 0 0 0 4.65E+07 3.25E+07 - - - 2.1331 0.9952 221125_WJC_METTL3_EV_vs_WT_F08.10252.10252.3 0.00261 Oct-48 R.LYK[136.11]EELEQTYHAK[136.11].L "sp|P20700|LMNB1_HUMAN,tr|E9PBF6|E9PBF6_HUMAN,tr|A0A0D9SFE5|A0A0D9SFE5_HUMAN" 3 1666.8537 1.51 114902 10252 3 1666.861597 556.6252 Lamin-B1 OS=Homo sapiens OX=9606 GN=LMNB1 PE=1 SV=2 5.5 2079.1 - 1.01E+06 - - - 4.7155 - 2.181 0.429 - 123.2 1 2 1 0.0079 13 0 0 0 4.52E+07 3.00E+07 - - - 5.435 0.9999 221125_WJC_METTL3_EV_vs_WT_F08.10254.10254.3 4.94E-11 14/52 K.SDVNK[136.11]EYYTQNMER[166.11].E "sp|Q9NW64|RBM22_HUMAN,tr|E5RJW4|E5RJW4_HUMAN,tr|E5RHA8|E5RHA8_HUMAN" 3 1793.8009 0.73 114904 10254 3 1793.80321 598.9409 Pre-mRNA-splicing factor RBM22 OS=Homo sapiens OX=9606 GN=RBM22 PE=1 SV=1 4.68 2079.2 - 1.75E+06 - - - 1.2694 - 2.872 0.625 - 256 1 2 1 0.0023 14 0 0 0 1.63E+07 2.25E+07 - - - 8.3112 0.9999 221125_WJC_METTL3_EV_vs_WT_F08.10263.10263.3 1.99E-05 13/76 K.TPPPR[166.11]PSPLEAGSDGC[160.03]EEPK[136.11].Q sp|Q9BUA3|SPNDC_HUMAN 1 2138.0069 4.01 114911 10263 3 2138.010973 713.6762 Spindlin interactor and repressor of chromatin-binding protein OS=Homo sapiens OX=9606 GN=SPINDOC PE=1 SV=3 4.41 2080.3 - 543346 - - - 1.9032 - 2.384 0.514 - 126.1 1 2 0 0.0041 20 0 0 0 6.44E+07 1.61E+07 - - - 6.3771 0.9308 221125_WJC_METTL3_EV_vs_WT_F08.10264.10264.4 0.0707 13/102 K.AGLGLGGRPPPQPPREER.A sp|Q6ZSJ8|CA122_HUMAN 1 1883.0126 0.84 114912 10264 4 1883.0182 471.7604 Uncharacterized protein C1orf122 OS=Homo sapiens OX=9606 GN=C1orf122 PE=4 SV=2 9.56 2080.4 - 424935 - - - 2.9856 - 2.001 0.217 - 95.3 1 2 1 0.0056 18 0 0 0 1.05E+07 1.25E+07 - - - 1.3508 0.9982 221125_WJC_METTL3_EV_vs_WT_F08.10269.10269.4 0.000336 14/90 R.SFGTEDR[166.11]PTDR[166.11]PIPPR[166.11].D "sp|Q8ND56|LS14A_HUMAN,tr|I3L4Q1|I3L4Q1_HUMAN,tr|A0A140TA76|A0A140TA76_HUMAN,tr|K7EMZ9|K7EMZ9_HUMAN" 4 1869.9476 0.99 114916 10269 4 1869.950036 468.4942 Protein LSM14 homolog A OS=Homo sapiens OX=9606 GN=LSM14A PE=1 SV=3 5.84 2081 - 1.02E+06 - - - 1.3188 - 2.19 0.267 - 123.8 1 2 0 0.0025 16 0 0 0 2.64E+07 2.67E+07 - - - 1.8254 0.9995 221125_WJC_METTL3_EV_vs_WT_F08.10270.10270.4 0.0186 15/90 R.SFGTEDRPTDRPIPPR.D "sp|Q8ND56|LS14A_HUMAN,tr|I3L4Q1|I3L4Q1_HUMAN,tr|A0A140TA76|A0A140TA76_HUMAN,tr|K7EMZ9|K7EMZ9_HUMAN" 4 1839.9228 0.99 114917 10270 4 1839.925495 460.988 Protein LSM14 homolog A OS=Homo sapiens OX=9606 GN=LSM14A PE=1 SV=3 5.84 2081.1 - 1.16E+06 - - - 1.4865 - 1.809 0.349 - 140.8 1 2 0 0.0027 16 0 0 0 2.64E+07 2.67E+07 - - - 2.4717 0.9866 221125_WJC_METTL3_EV_vs_WT_F08.10272.10272.4 7.44E-06 15/84 A.TVEEVDAAMNAR[166.11]PHK[136.11].V "sp|P09651|ROA1_HUMAN,tr|A0A7I2YQX9|A0A7I2YQX9_HUMAN,tr|A0A7I2V3W4|A0A7I2V3W4_HUMAN,tr|F8W646|F8W646_HUMAN,tr|F8VZ49|F8VZ49_HUMAN,tr|A0A7I2V3R8|A0A7I2V3R8_HUMAN,tr|F8W6I7|F8W6I7_HUMAN,tr|F8VYN5|F8VYN5_HUMAN,tr|A0A7I2V2L6|A0A7I2V2L6_HUMAN,tr|A0A7I2V3C7|A0A7I2V3C7_HUMAN,tr|A0A7I2V3W0|A0A7I2V3W0_HUMAN,tr|A0A7I2YQV3|A0A7I2YQV3_HUMAN,tr|A0A2R8Y4L2|A0A2R8Y4L2_HUMAN,tr|A0A7I2V2Z4|A0A7I2V2Z4_HUMAN,tr|A0A7I2V4M0|A0A7I2V4M0_HUMAN" 15 1684.8322 0.9 114919 10272 4 1684.834013 422.2153 Heterogeneous nuclear ribonucleoprotein A1 OS=Homo sapiens OX=9606 GN=HNRNPA1 PE=1 SV=5 5.41 2081.3 - 413245 - - - 1.0915 - 2.444 0.411 - 165.4 1 1 0 0.0018 15 0 0 0 4.13E+07 4.61E+07 - - - 3.1226 0.9999 221125_WJC_METTL3_EV_vs_WT_F08.10277.10277.3 1.96E-06 15/36 R.KVELPVPTHR.R "sp|Q9BYD3|RM04_HUMAN,tr|X6RAY8|X6RAY8_HUMAN,tr|K7ES61|K7ES61_HUMAN,tr|K7ELF1|K7ELF1_HUMAN,tr|K7ELQ0|K7ELQ0_HUMAN,tr|K7EKI4|K7EKI4_HUMAN" 6 1174.6822 1.45 114922 10277 3 1174.68438 392.568 "39S ribosomal protein L4, mitochondrial OS=Homo sapiens OX=9606 GN=MRPL4 PE=1 SV=1" 8.75 2082 - 1.06E+06 - - - 1.8201 - 2.582 0.424 - 441.2 1 2 0 0.0021 10 0 0 0 3.40E+07 2.34E+07 - - - 6.0368 1 221125_WJC_METTL3_EV_vs_WT_F08.10285.10285.3 4.80E-09 18/44 R.RVDPDVAQHWAK.S "sp|Q9NYR9|KBRS2_HUMAN,tr|K7ERG2|K7ERG2_HUMAN,tr|H7BXP1|H7BXP1_HUMAN" 3 1420.7211 1.11 114928 10285 3 1420.724972 474.581 NF-kappa-B inhibitor-interacting Ras-like protein 2 OS=Homo sapiens OX=9606 GN=NKIRAS2 PE=1 SV=1 6.75 2083.1 - 756974 - - - 2.6923 - 2.967 0.562 - 569.6 1 2 0 0.0038 12 0 0 0 1.15E+07 1.04E+07 - - - 7.8192 0.9998 221125_WJC_METTL3_EV_vs_WT_F08.10286.10286.3 0.000674 18/68 R.IPPLNPGQGPGPNKGDSR.G sp|Q9C0J8|WDR33_HUMAN 1 1799.9278 1.33 114929 10286 3 1799.929552 600.9832 pre-mRNA 3' end processing protein WDR33 OS=Homo sapiens OX=9606 GN=WDR33 PE=1 SV=2 8.75 2083.2 - 337111 - - - 0.9484 - 2.946 0.454 - 318.1 1 2 1 0.0017 18 0 0 0 2.16E+07 1.63E+07 - - - 6.2916 1 221125_WJC_METTL3_EV_vs_WT_F08.10288.10288.3 1.20E-07 17/60 K.RPELLTHSTTEVTQPR.T "sp|P78347|GTF2I_HUMAN,tr|A0A494C0Q7|A0A494C0Q7_HUMAN,tr|A0A494C1K3|A0A494C1K3_HUMAN" 3 1863.9803 1.49 114931 10288 3 1863.98303 622.334 General transcription factor II-I OS=Homo sapiens OX=9606 GN=GTF2I PE=1 SV=2 6.76 2083.4 - 441939 - - - 1.478 - 3.245 0.584 - 405.8 1 2 0 0.0028 16 0 0 0 4.81E+08 3.22E+08 - - - 8.0706 1 221125_WJC_METTL3_EV_vs_WT_F08.10290.10290.2 1.59E-07 24-Nov K.NKENFELQAAQEK.E "sp|O75179|ANR17_HUMAN,tr|H0YM23|H0YM23_HUMAN" 2 1547.758 0.99 114933 10290 2 1547.75968 774.8863 Ankyrin repeat domain-containing protein 17 OS=Homo sapiens OX=9606 GN=ANKRD17 PE=1 SV=3 4.79 2083.7 - 135919 - - - 1.0945 - 2.44 0.6 - 388.4 1 2 1 0.0017 13 0 0 0 3.54E+06 3.59E+06 - - - 5.7614 1 221125_WJC_METTL3_EV_vs_WT_F08.10291.10291.2 4.36E-11 30-Dec K.NEDVC[160.03]SC[160.03]STDTSEVPR.W sp|P49790|NU153_HUMAN 1 1854.736 1.27 114934 10291 2 1854.738637 928.3753 Nuclear pore complex protein Nup153 OS=Homo sapiens OX=9606 GN=NUP153 PE=1 SV=2 3.92 2083.8 - 115821 - - - 1.418 - 2.955 0.777 - 451.1 1 2 0 0.0026 16 0 0 0 7.12E+06 5.62E+06 - - - 7.4429 1 221125_WJC_METTL3_EV_vs_WT_F08.10294.10294.3 1.64E-08 15/52 K.K[136.11]GPGEVAGTVTGQK[136.11].R "sp|Q86U44|MTA70_HUMAN,tr|F5H6D8|F5H6D8_HUMAN,tr|H0YFV6|H0YFV6_HUMAN,tr|B4DTN4|B4DTN4_HUMAN" 4 1343.738 0 114935 10294 3 1343.741577 448.9199 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 8.59 2084.2 - 753422 - - - 2.6776 - 2.992 0.561 - 368.2 1 2 0 0.0036 14 0 0 0 9.21E+04 2.15E+07 - - - 7.7061 1 221125_WJC_METTL3_EV_vs_WT_F08.10295.10295.3 2.35E-19 33/92 R.GPGASGEQPEPGEAAAGGAAEEAR.R sp|Q9H3P7|GCP60_HUMAN 1 2164.9621 1.31 114936 10295 3 2164.966551 722.6613 Golgi resident protein GCP60 OS=Homo sapiens OX=9606 GN=ACBD3 PE=1 SV=4 3.98 2084.4 - 753458 - - - 2.0476 - 5.229 0.745 - 1094.3 1 2 0 0.0044 24 0 0 0 7.99E+06 6.11E+06 - - - 10.6869 0.9995 221125_WJC_METTL3_EV_vs_WT_F08.10297.10297.3 0.0771 Dec-44 R.K[136.11]SDLIQDEALR[166.11]R[166.11].A "sp|Q96MF7|NSE2_HUMAN,tr|E5RFJ1|E5RFJ1_HUMAN" 2 1470.8149 1.37 114938 10297 3 1470.818843 491.2789 E3 SUMO-protein ligase NSE2 OS=Homo sapiens OX=9606 GN=NSMCE2 PE=1 SV=2 6.12 2084.6 - 487938 - - - 2.6937 - 2.146 0.36 - 260.6 1 2 0 0.004 12 0 0 0 1.52E+07 1.11E+07 - - - 4.6691 0.9997 221125_WJC_METTL3_EV_vs_WT_F08.10299.10299.3 2.16E-07 15/48 R.HRLDLGEDYPSGK.K sp|O43143|DHX15_HUMAN 1 1485.7212 1.46 114940 10299 3 1485.725105 496.2477 Pre-mRNA-splicing factor ATP-dependent RNA helicase DHX15 OS=Homo sapiens OX=9606 GN=DHX15 PE=1 SV=2 5.38 2084.8 - 229178 - - - 2.6243 - 2.867 0.518 - 309.1 1 2 1 0.0039 13 0 0 0 1.40E+07 9.60E+06 - - - 7.1698 1 221125_WJC_METTL3_EV_vs_WT_F08.10301.10301.2 7.37E-13 14/30 R.DGQVINETSQHHDDLE.- sp|P08670|VIME_HUMAN 1 1835.7922 - 114942 10301 2 1835.796826 918.9034 Vimentin OS=Homo sapiens OX=9606 GN=VIM PE=1 SV=4 4.28 2085.1 - 169266 - - - 2.5204 - 2.844 0.759 - 406.8 1 2 0 0.0046 16 0 0 0 - - - - - 7.2152 0.9999 221125_WJC_METTL3_EV_vs_WT_F08.10302.10302.2 2.31E-07 Sep-46 R.GPGASGEQPEPGEAAAGGAAEEAR[166.11].R sp|Q9H3P7|GCP60_HUMAN 1 2174.9704 0.76 114943 10302 2 2174.971174 1088.4925 Golgi resident protein GCP60 OS=Homo sapiens OX=9606 GN=ACBD3 PE=1 SV=4 3.98 2085.2 - 146709 - - - 0.3614 - 2.086 0.65 - 103.2 1 2 0 0.0008 24 0 0 0 7.38E+05 9.76E+05 - - - 5.6493 0.9998 221125_WJC_METTL3_EV_vs_WT_F08.10304.10304.3 3.26E-07 Sep-60 K.NEDVC[160.03]SC[160.03]STDTSEVPR.W sp|P49790|NU153_HUMAN 1 1854.736 0.36 114945 10304 3 1854.743845 619.2526 Nuclear pore complex protein Nup153 OS=Homo sapiens OX=9606 GN=NUP153 PE=1 SV=2 3.92 2085.5 - 106597 - - - 4.2259 - 2.329 0.552 - 87 1 2 0 0.0078 16 0 0 0 3.64E+06 1.02E+07 - - - 6.8614 0.9992 221125_WJC_METTL3_EV_vs_WT_F08.10308.10308.3 0.0124 15/44 R.KSDLIQDEALRR.A "sp|Q96MF7|NSE2_HUMAN,tr|E5RFJ1|E5RFJ1_HUMAN" 2 1442.7841 1.37 114947 10308 3 1442.787004 481.9353 E3 SUMO-protein ligase NSE2 OS=Homo sapiens OX=9606 GN=NSMCE2 PE=1 SV=2 6.12 2086 - 1.28E+06 - - - 1.9844 - 2.158 0.299 - 411.5 1 2 0 0.0029 12 0 0 0 1.52E+07 1.11E+07 - - - 4.0048 0.8395 221125_WJC_METTL3_EV_vs_WT_F08.10310.10310.3 1.13E-05 13/56 R.TPTQTNGSNVPFK[136.11]PR[166.11].G "sp|P78347|GTF2I_HUMAN,tr|A0A494C1K3|A0A494C1K3_HUMAN" 2 1660.8652 -1 114949 10310 3 1661.852714 554.629 General transcription factor II-I OS=Homo sapiens OX=9606 GN=GTF2I PE=1 SV=2 11 2086.2 - 2.08E+06 - - - 594.5853 - 2.331 0.487 - 152.8 1 2 0 0.9875 15 0 0 0 0.00E+00 0.00E+00 - - - 5.9043 0.9942 221125_WJC_METTL3_EV_vs_WT_F08.10311.10311.3 0.000414 20/56 A.TVEEVDAAMNAR[166.11]PHK[136.11].V "sp|P09651|ROA1_HUMAN,tr|A0A7I2YQX9|A0A7I2YQX9_HUMAN,tr|A0A7I2V3W4|A0A7I2V3W4_HUMAN,tr|F8W646|F8W646_HUMAN,tr|F8VZ49|F8VZ49_HUMAN,tr|A0A7I2V3R8|A0A7I2V3R8_HUMAN,tr|F8W6I7|F8W6I7_HUMAN,tr|F8VYN5|F8VYN5_HUMAN,tr|A0A7I2V2L6|A0A7I2V2L6_HUMAN,tr|A0A7I2V3C7|A0A7I2V3C7_HUMAN,tr|A0A7I2V3W0|A0A7I2V3W0_HUMAN,tr|A0A7I2YQV3|A0A7I2YQV3_HUMAN,tr|A0A2R8Y4L2|A0A2R8Y4L2_HUMAN,tr|A0A7I2V2Z4|A0A7I2V2Z4_HUMAN,tr|A0A7I2V4M0|A0A7I2V4M0_HUMAN" 15 1684.8322 0.87 114950 10311 3 1684.834748 562.618 Heterogeneous nuclear ribonucleoprotein A1 OS=Homo sapiens OX=9606 GN=HNRNPA1 PE=1 SV=5 5.41 2086.2 - 1.20E+06 - - - 1.5277 - 3.129 0.421 - 324.4 1 1 0 0.0026 15 0 0 0 3.73E+07 4.31E+07 - - - 6.2096 1 221125_WJC_METTL3_EV_vs_WT_F08.10312.10312.4 2.61E-09 19/90 K.RPELLTHSTTEVTQPR.T "sp|P78347|GTF2I_HUMAN,tr|A0A494C0Q7|A0A494C0Q7_HUMAN,tr|A0A494C1K3|A0A494C1K3_HUMAN" 3 1863.9803 1.48 114951 10312 4 1863.984057 467.0023 General transcription factor II-I OS=Homo sapiens OX=9606 GN=GTF2I PE=1 SV=2 6.76 2086.3 - 1.11E+06 - - - 2.029 - 3.52 0.529 - 338.2 1 2 0 0.0038 16 0 0 0 2.47E+08 1.67E+08 - - - 4.2727 0.9977 221125_WJC_METTL3_EV_vs_WT_F08.10314.10314.4 1.74E-05 17/120 K.LEPGGFGEKPVRPGGGDTSPR.Y "sp|Q5JSZ5|PRC2B_HUMAN,tr|A0A804HKC3|A0A804HKC3_HUMAN,tr|A0A804HJR4|A0A804HJR4_HUMAN" 3 2109.0603 1.65 114953 10314 4 2109.064796 528.2724 Protein PRRC2B OS=Homo sapiens OX=9606 GN=PRRC2B PE=1 SV=2 6.18 2086.6 - 435252 - - - 2.1242 - 2.878 0.27 - 188.1 1 2 0 0.0045 21 0 0 0 1.11E+07 6.70E+06 - - - 1.9244 1 221125_WJC_METTL3_EV_vs_WT_F08.10319.10319.2 1.51E-11 30-Nov K.NEDVC[160.03]SC[160.03]STDTSEVPR[166.11].W sp|P49790|NU153_HUMAN 1 1864.7443 1.27 114958 10319 2 1864.744326 933.3794 Nuclear pore complex protein Nup153 OS=Homo sapiens OX=9606 GN=NUP153 PE=1 SV=2 3.92 2087.2 - 302574 - - - 0.0263 - 2.808 0.796 - 369 1 2 0 0.0001 16 0 0 0 7.12E+06 5.62E+06 - - - 7.4586 1 221125_WJC_METTL3_EV_vs_WT_F08.10324.10324.3 2.42E-12 22/76 K.TPPPRPSPLEAGSDGC[160.03]EEPK.Q sp|Q9BUA3|SPNDC_HUMAN 1 2119.9844 16.72 114962 10324 3 2119.9862 707.6688 Spindlin interactor and repressor of chromatin-binding protein OS=Homo sapiens OX=9606 GN=SPINDOC PE=1 SV=3 4.41 2087.9 - 1.24E+06 - - - 0.833 - 3.647 0.578 - 420.9 1 2 0 0.0018 20 0 0 0 2.36E+07 1.41E+06 - - - 8.1227 1 221125_WJC_METTL3_EV_vs_WT_F08.10327.10327.3 1.96E-09 16/40 R.HPGSFDVVHVK[136.11].D "sp|P62701|RS4X_HUMAN,sp|P22090|RS4Y1_HUMAN,tr|C9JEH7|C9JEH7_HUMAN" 3 1228.6444 0.99 114964 10327 3 1228.64303 410.5554 "40S ribosomal protein S4, X isoform OS=Homo sapiens OX=9606 GN=RPS4X PE=1 SV=2" 6.92 2088.2 - 2.33E+06 - - - -1.1199 - 2.82 0.633 - 309 1 2 0 -0.0014 11 0 0 0 8.67E+07 8.74E+07 - - - 8.5421 0.9683 221125_WJC_METTL3_EV_vs_WT_F08.10328.10328.4 6.56E-05 15/84 A.TVEEVDAAMNARPHK.V "sp|P09651|ROA1_HUMAN,tr|A0A7I2YQX9|A0A7I2YQX9_HUMAN,tr|A0A7I2V3W4|A0A7I2V3W4_HUMAN,tr|F8W646|F8W646_HUMAN,tr|F8VZ49|F8VZ49_HUMAN,tr|A0A7I2V3R8|A0A7I2V3R8_HUMAN,tr|F8W6I7|F8W6I7_HUMAN,tr|F8VYN5|F8VYN5_HUMAN,tr|A0A7I2V2L6|A0A7I2V2L6_HUMAN,tr|A0A7I2V3C7|A0A7I2V3C7_HUMAN,tr|A0A7I2V3W0|A0A7I2V3W0_HUMAN,tr|A0A7I2YQV3|A0A7I2YQV3_HUMAN,tr|A0A2R8Y4L2|A0A2R8Y4L2_HUMAN,tr|A0A7I2V2Z4|A0A7I2V2Z4_HUMAN,tr|A0A7I2V4M0|A0A7I2V4M0_HUMAN" 15 1666.8097 0.96 114965 10328 4 1666.801679 417.7097 Heterogeneous nuclear ribonucleoprotein A1 OS=Homo sapiens OX=9606 GN=HNRNPA1 PE=1 SV=5 5.41 2088.3 - 2.18E+06 - - - -4.8146 - 3.113 0.531 - 233.2 1 1 0 -0.008 15 0 0 0 4.05E+07 4.24E+07 - - - 4.2519 0.9997 221125_WJC_METTL3_EV_vs_WT_F08.10329.10329.4 5.78E-05 Nov-78 K.YC[160.03]VEEEEKAAEMHK.M "sp|P78347|GTF2I_HUMAN,tr|C9J6M0|C9J6M0_HUMAN,tr|A0A494C1K3|A0A494C1K3_HUMAN" 3 1751.7495 1.3 114966 10329 4 1751.748607 438.9446 General transcription factor II-I OS=Homo sapiens OX=9606 GN=GTF2I PE=1 SV=2 4.64 2088.3 - 2.15E+06 - - - -0.4938 - 2.306 0.443 - 39.7 1 2 1 -0.0009 14 0 0 0 2.37E+08 1.82E+08 - - - 3.3857 1 221125_WJC_METTL3_EV_vs_WT_F08.10330.10330.3 1.55E-06 17/40 R.HPGSFDVVHVK.D "sp|P62701|RS4X_HUMAN,sp|P22090|RS4Y1_HUMAN,tr|C9JEH7|C9JEH7_HUMAN" 3 1220.6302 0.99 114967 10330 3 1220.62867 407.884 "40S ribosomal protein S4, X isoform OS=Homo sapiens OX=9606 GN=RPS4X PE=1 SV=2" 6.92 2088.4 - 2.00E+06 - - - -1.2584 - 2.727 0.558 - 333.9 1 2 0 -0.0015 11 0 0 0 8.66E+07 8.74E+07 - - - 7.6106 0.9517 221125_WJC_METTL3_EV_vs_WT_F08.10333.10333.3 0.0967 Dec-60 R.SFGTEDR[166.11]PTDR[166.11]PIPPR[166.11].D "sp|Q8ND56|LS14A_HUMAN,tr|I3L4Q1|I3L4Q1_HUMAN,tr|A0A140TA76|A0A140TA76_HUMAN,tr|K7EMZ9|K7EMZ9_HUMAN" 4 1869.9476 0.66 114970 10333 3 1869.942975 624.3231 Protein LSM14 homolog A OS=Homo sapiens OX=9606 GN=LSM14A PE=1 SV=3 5.84 2088.8 - 869636 - - - -2.4573 - 1.52 0.16 - 75.8 1 2 0 -0.0046 16 0 0 0 1.64E+07 2.49E+07 - - - 1.3969 0.8581 221125_WJC_METTL3_EV_vs_WT_F08.10334.10334.3 0.021 Nov-64 W.NKPLTSFGSAPSSEGAK.N "sp|Q9Y520|PRC2C_HUMAN,tr|E7EPN9|E7EPN9_HUMAN,tr|H7C5N8|H7C5N8_HUMAN,tr|A0A2R8Y7F4|A0A2R8Y7F4_HUMAN,tr|A0A2R8YET2|A0A2R8YET2_HUMAN" 5 1676.837 2.11 114971 10334 3 1676.838473 559.9529 Protein PRRC2C OS=Homo sapiens OX=9606 GN=PRRC2C PE=1 SV=4 8.59 2088.9 - 452049 - - - 0.8999 - 2.063 0.239 - 108.5 1 1 0 0.0015 17 0 0 0 1.41E+07 6.66E+06 - - - 3.0336 1 221125_WJC_METTL3_EV_vs_WT_F08.10335.10335.2 8.86E-10 14/24 K.QEYDESGPSIVHR[166.11].K "sp|Q6S8J3|POTEE_HUMAN,sp|P63261|ACTG_HUMAN,sp|Q9BYX7|ACTBM_HUMAN,sp|P60709|ACTB_HUMAN,sp|A5A3E0|POTEF_HUMAN,sp|P0CG38|POTEI_HUMAN,sp|P0CG39|POTEJ_HUMAN,tr|A0A2R8YFE2|A0A2R8YFE2_HUMAN,tr|A0A804GS07|A0A804GS07_HUMAN,tr|A0A6Q8PFE4|A0A6Q8PFE4_HUMAN,tr|I3L4N8|I3L4N8_HUMAN" 11 1525.7037 5.06 114972 10335 2 1525.700813 763.8591 POTE ankyrin domain family member E OS=Homo sapiens OX=9606 GN=POTEE PE=2 SV=3 4.65 2089.1 - 449876 - - - -1.8634 - 2.847 0.649 - 997.7 1 2 0 -0.0028 13 0 0 0 7.34E+07 1.45E+07 - - - 6.5189 0.9985 221125_WJC_METTL3_EV_vs_WT_F08.10338.10338.3 0.00197 Oct-48 R.LYKEELEQTYHAK.L "sp|P20700|LMNB1_HUMAN,tr|E9PBF6|E9PBF6_HUMAN,tr|A0A0D9SFE5|A0A0D9SFE5_HUMAN" 3 1650.8253 1.35 114974 10338 3 1650.824756 551.2824 Lamin-B1 OS=Homo sapiens OX=9606 GN=LMNB1 PE=1 SV=2 5.5 2089.4 - 995826 - - - -0.3519 - 1.889 0.351 - 100.7 1 2 1 -0.0006 13 0 0 0 4.70E+07 3.47E+07 - - - 4.1777 0.9998 221125_WJC_METTL3_EV_vs_WT_F08.10340.10340.4 7.67E-06 14/78 K.YC[160.03]VEEEEK[136.11]AAEMHK[136.11].M "sp|P78347|GTF2I_HUMAN,tr|C9J6M0|C9J6M0_HUMAN,tr|A0A494C1K3|A0A494C1K3_HUMAN" 3 1767.7779 1.4 114975 10340 4 1767.772671 442.9517 General transcription factor II-I OS=Homo sapiens OX=9606 GN=GTF2I PE=1 SV=2 4.64 2089.6 - 4.65E+06 - - - -2.9421 - 2.891 0.578 - 102.1 1 2 1 -0.0052 14 0 0 0 2.36E+08 1.69E+08 - - - 4.6418 1 221125_WJC_METTL3_EV_vs_WT_F08.10341.10341.3 2.14E-07 13/52 K.YC[160.03]VEEEEKAAEMHK.M "sp|P78347|GTF2I_HUMAN,tr|C9J6M0|C9J6M0_HUMAN,tr|A0A494C1K3|A0A494C1K3_HUMAN" 3 1751.7495 1.36 114976 10341 3 1751.748765 584.9238 General transcription factor II-I OS=Homo sapiens OX=9606 GN=GTF2I PE=1 SV=2 4.64 2089.6 - 4.48E+06 - - - -0.4036 - 2.889 0.709 - 126 1 2 1 -0.0007 14 0 0 0 2.08E+08 1.53E+08 - - - 9.2639 0.9973 221125_WJC_METTL3_EV_vs_WT_F08.10343.10343.3 0.00728 15/32 R.R[166.11]K[136.11]VDWLTEK[136.11].M "sp|Q14240|IF4A2_HUMAN,sp|P38919|IF4A3_HUMAN,sp|P60842|IF4A1_HUMAN,tr|J3QL52|J3QL52_HUMAN,tr|J3KT12|J3KT12_HUMAN,tr|J3QS69|J3QS69_HUMAN,tr|I3L3H2|I3L3H2_HUMAN,tr|J3QL43|J3QL43_HUMAN,tr|J3KTN0|J3KTN0_HUMAN,tr|E7EQG2|E7EQG2_HUMAN,tr|J3KSZ0|J3KSZ0_HUMAN" 11 1199.6873 1.12 114978 10343 3 1199.68428 400.903 Eukaryotic initiation factor 4A-II OS=Homo sapiens OX=9606 GN=EIF4A2 PE=1 SV=2 8.59 2089.9 - 1.49E+06 - - - -2.4982 - 2.533 0.28 - 461.2 1 2 1 -0.003 9 0 0 0 2.15E+07 1.91E+07 - - - 4.4619 1 221125_WJC_METTL3_EV_vs_WT_F08.10344.10344.2 1.54E-05 16/24 Q.VINETSQHHDDLE.- sp|P08670|VIME_HUMAN 1 1535.6852 - 114979 10344 2 1535.680545 768.8499 Vimentin OS=Homo sapiens OX=9606 GN=VIM PE=1 SV=4 4.52 2090 - 1.23E+06 - - - -3.041 - 2.52 0.606 - 526.3 1 1 0 -0.0047 13 0 0 0 - - - - - 5.8876 1 221125_WJC_METTL3_EV_vs_WT_F08.10346.10346.3 4.74E-07 23/60 R.NTVSQSISGDPEIDK[136.11]K[136.11].L "sp|Q9BY44|EIF2A_HUMAN,tr|F8WAE5|F8WAE5_HUMAN" 2 1732.8814 0.39 114981 10346 3 1732.88394 578.6344 Eukaryotic translation initiation factor 2A OS=Homo sapiens OX=9606 GN=EIF2A PE=1 SV=3 4.56 2090.3 - 1.16E+06 - - - 1.4612 - 3.547 0.56 - 756.6 1 2 0 0.0025 16 0 0 0 2.03E+07 5.25E+07 - - - 8.0314 1 221125_WJC_METTL3_EV_vs_WT_F08.10353.10353.3 1.50E-09 14/52 K.YC[160.03]VEEEEK[136.11]AAEMHK[136.11].M "sp|P78347|GTF2I_HUMAN,tr|C9J6M0|C9J6M0_HUMAN,tr|A0A494C1K3|A0A494C1K3_HUMAN" 3 1767.7779 1.43 114986 10353 3 1767.773404 590.2666 General transcription factor II-I OS=Homo sapiens OX=9606 GN=GTF2I PE=1 SV=2 4.64 2091 - 5.38E+06 - - - -2.5275 - 2.863 0.649 - 136.6 1 2 1 -0.0045 14 0 0 0 2.07E+08 1.45E+08 - - - 8.5698 0.9996 221125_WJC_METTL3_EV_vs_WT_F08.10354.10354.3 0.000612 18/32 R.RKVDWLTEK.M "sp|Q14240|IF4A2_HUMAN,sp|P38919|IF4A3_HUMAN,sp|P60842|IF4A1_HUMAN,tr|J3QL52|J3QL52_HUMAN,tr|J3KT12|J3KT12_HUMAN,tr|J3QS69|J3QS69_HUMAN,tr|I3L3H2|I3L3H2_HUMAN,tr|J3QL43|J3QL43_HUMAN,tr|J3KTN0|J3KTN0_HUMAN,tr|E7EQG2|E7EQG2_HUMAN,tr|J3KSZ0|J3KSZ0_HUMAN" 11 1173.6506 1.11 114987 10354 3 1173.648132 392.2241 Eukaryotic initiation factor 4A-II OS=Homo sapiens OX=9606 GN=EIF4A2 PE=1 SV=2 8.59 2091.1 - 1.97E+06 - - - -2.1088 - 3.144 0.364 - 845.8 1 2 1 -0.0025 9 0 0 0 2.14E+07 1.93E+07 - - - 6.0498 0.9999 221125_WJC_METTL3_EV_vs_WT_F08.10355.10355.3 3.19E-08 20/68 K.LASSLPDNKQEENTALNK.D sp|Q5VT06|CE350_HUMAN 1 1970.9909 2.79 114988 10355 3 1970.985909 658.0042 Centrosome-associated protein 350 OS=Homo sapiens OX=9606 GN=CEP350 PE=1 SV=1 4.68 2091.2 - 1.93E+06 - - - -2.5317 - 3.914 0.543 - 544.4 1 2 1 -0.005 18 0 0 0 2.19E+07 7.86E+06 - - - 7.9904 0.9998 221125_WJC_METTL3_EV_vs_WT_F08.10359.10359.2 0.00918 18-Dec R.YPDGIISK[136.11]PK[136.11].N sp|Q86U44|MTA70_HUMAN 1 1132.6463 0.001 114990 10359 2 1132.643978 567.3304 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 8.5 2091.7 - 7.43E+06 - - - -2.0589 - 2.084 0.552 - 499.3 1 2 0 -0.0023 10 0 0 0 0.00E+00 3.73E+08 - - - 5.167 0.9999 221125_WJC_METTL3_EV_vs_WT_F08.10367.10367.3 0.00184 14/40 R.KQQQELHLALK.Q sp|Q96EU6|RRP36_HUMAN 1 1334.767 1.39 114996 10367 3 1334.763944 445.9296 Ribosomal RNA processing protein 36 homolog OS=Homo sapiens OX=9606 GN=RRP36 PE=1 SV=1 8.6 2092.6 - 1.64E+06 - - - -2.315 - 3.076 0.437 - 308.8 1 2 0 -0.0031 11 0 0 0 2.59E+07 1.86E+07 - - - 6.6033 0.9999 221125_WJC_METTL3_EV_vs_WT_F08.10375.10375.3 2.11E-05 14/48 K.EFHLNESGDPSSK.S "sp|Q01105|SET_HUMAN,sp|P0DME0|SETLP_HUMAN,tr|A0A0C4DFV9|A0A0C4DFV9_HUMAN" 3 1445.6423 0.99 115002 10375 3 1445.639303 482.888 Protein SET OS=Homo sapiens OX=9606 GN=SET PE=1 SV=3 4.65 2093.6 - 2.07E+06 - - - -2.0641 - 2.525 0.442 - 260.9 1 2 0 -0.003 13 0 0 0 1.52E+08 1.54E+08 - - - 5.9783 0.9998 221125_WJC_METTL3_EV_vs_WT_F08.10378.10378.3 0.000366 20/36 R.KQVEELFERK.Y "sp|P78347|GTF2I_HUMAN,tr|A0A494C1K3|A0A494C1K3_HUMAN" 2 1304.7089 1.92 115004 10378 3 1304.706402 435.9102 General transcription factor II-I OS=Homo sapiens OX=9606 GN=GTF2I PE=1 SV=2 6.23 2093.9 - 1.07E+06 - - - -1.877 - 3.181 0.278 - 835.3 1 2 0 -0.0024 10 0 0 0 3.31E+07 1.73E+07 - - - 5.0183 1 221125_WJC_METTL3_EV_vs_WT_F08.10381.10381.3 2.85E-07 Nov-60 R.DGQVINETSQHHDDLE.- sp|P08670|VIME_HUMAN 1 1835.7922 - 115006 10381 3 1835.788039 612.938 Vimentin OS=Homo sapiens OX=9606 GN=VIM PE=1 SV=4 4.28 2094.3 - 5.73E+08 - - - -2.2661 - 2.673 0.55 - 154.9 1 2 0 -0.0042 16 0 0 0 - - - - - 7.1936 1 221125_WJC_METTL3_EV_vs_WT_F08.10382.10382.3 1.89E-11 16/48 K.QEYDESGPSIVHR.K "sp|Q6S8J3|POTEE_HUMAN,sp|P63261|ACTG_HUMAN,sp|Q9BYX7|ACTBM_HUMAN,sp|P60709|ACTB_HUMAN,sp|A5A3E0|POTEF_HUMAN,sp|P0CG38|POTEI_HUMAN,sp|P0CG39|POTEJ_HUMAN,tr|A0A2R8YFE2|A0A2R8YFE2_HUMAN,tr|A0A804GS07|A0A804GS07_HUMAN,tr|A0A6Q8PFE4|A0A6Q8PFE4_HUMAN,tr|I3L4N8|I3L4N8_HUMAN" 11 1515.6954 1.11 115007 10382 3 1515.693002 506.2391 POTE ankyrin domain family member E OS=Homo sapiens OX=9606 GN=POTEE PE=2 SV=3 4.65 2094.3 - 1.12E+07 - - - -1.5729 - 2.898 0.645 - 438.8 1 2 0 -0.0024 13 0 0 0 2.84E+08 2.56E+08 - - - 8.6153 1 221125_WJC_METTL3_EV_vs_WT_F08.10388.10388.3 3.19E-06 22/60 R.KQPPVSPGTALVGSQK.E sp|P17096|HMGA1_HUMAN 1 1592.8886 0.86 115010 10388 3 1592.887879 531.9701 High mobility group protein HMG-I\HMG-Y OS=Homo sapiens OX=9606 GN=HMGA1 PE=1 SV=3 10 2095 - 1.41E+06 - - - -0.4564 - 4.295 0.546 - 686.6 1 2 0 -0.0007 16 0 0 0 1.33E+08 1.54E+08 - - - 8.3668 1 221125_WJC_METTL3_EV_vs_WT_F08.10390.10390.3 4.12E-10 22/52 K.C[160.03]LDENLEDASQC[160.03]K[136.11]K[136.11].L sp|Q5JTJ3|COA6_HUMAN 1 1724.768 0.75 115012 10390 3 1724.763212 575.93 Cytochrome c oxidase assembly factor 6 homolog OS=Homo sapiens OX=9606 GN=COA6 PE=1 SV=1 4.32 2095.1 - 1.45E+06 - - - -2.7963 - 3.803 0.678 - 545 1 2 0 -0.0048 14 0 0 0 5.41E+07 7.20E+07 - - - 9.6476 1 221125_WJC_METTL3_EV_vs_WT_F08.10394.10394.3 2.50E-09 19/52 H.SC[160.03]NWVAASGPC[160.03]DK[136.11]R[166.11].F sp|Q9H7S9|ZN703_HUMAN 1 1624.7205 1.56 115016 10394 3 1624.714712 542.5808 Zinc finger protein 703 OS=Homo sapiens OX=9606 GN=ZNF703 PE=1 SV=1 7.79 2095.6 - 967379 - - - -3.5717 - 3.975 0.683 - 760.4 1 1 0 -0.0058 14 0 0 0 4.31E+07 2.76E+07 - - - 9.8206 1 221125_WJC_METTL3_EV_vs_WT_F08.10397.10397.3 6.27E-09 15/44 R.K[136.11]SNFAEALAAHK[136.11].Y "sp|P07237|PDIA1_HUMAN,tr|A0A7P0TA97|A0A7P0TA97_HUMAN,tr|A0A7P0T8C0|A0A7P0T8C0_HUMAN,tr|H7BZ94|H7BZ94_HUMAN,tr|A0A7P0Z4B2|A0A7P0Z4B2_HUMAN,tr|A0A7P0TA71|A0A7P0TA71_HUMAN,tr|I3L4M2|I3L4M2_HUMAN,tr|A0A7P0T9D6|A0A7P0T9D6_HUMAN,tr|A0A7P0T9K9|A0A7P0T9K9_HUMAN,tr|H0Y3Z3|H0Y3Z3_HUMAN,tr|A0A7P0Z4S2|A0A7P0Z4S2_HUMAN,tr|I3NI03|I3NI03_HUMAN,tr|A0A7P0TA35|A0A7P0TA35_HUMAN,tr|A0A7P0TAX9|A0A7P0TAX9_HUMAN,tr|I3L1Y5|I3L1Y5_HUMAN,tr|I3L514|I3L514_HUMAN,tr|A0A7P0Z476|A0A7P0Z476_HUMAN,tr|A0A7P0Z4F8|A0A7P0Z4F8_HUMAN,tr|A0A7P0TBP8|A0A7P0TBP8_HUMAN,tr|A0A7P0TB26|A0A7P0TB26_HUMAN,tr|A0A7P0T9U6|A0A7P0T9U6_HUMAN,tr|A0A7P0T9E3|A0A7P0T9E3_HUMAN,tr|A0A7P0TBA3|A0A7P0TBA3_HUMAN,tr|I3L0S0|I3L0S0_HUMAN,tr|I3L3P5|I3L3P5_HUMAN,tr|A0A7P0T940|A0A7P0T940_HUMAN,tr|A0A7P0T8J3|A0A7P0T8J3_HUMAN,tr|A0A7P0Z4J0|A0A7P0Z4J0_HUMAN,tr|A0A7P0T9S9|A0A7P0T9S9_HUMAN,tr|A0A7P0T8X1|A0A7P0T8X1_HUMAN,tr|I3L3U6|I3L3U6_HUMAN" 31 1301.7063 1.23 115017 10397 3 1301.70279 434.9094 Protein disulfide-isomerase OS=Homo sapiens OX=9606 GN=P4HB PE=1 SV=3 8.6 2095.9 - 2.32E+06 - - - -2.6849 - 2.937 0.556 - 388.7 1 2 0 -0.0035 12 0 0 0 1.50E+08 1.21E+08 - - - 7.7242 1 221125_WJC_METTL3_EV_vs_WT_F08.10398.10398.3 1.65E-08 18/60 R.K[136.11]QPPVSPGTALVGSQK[136.11].E sp|P17096|HMGA1_HUMAN 1 1608.917 0.87 115018 10398 3 1608.914438 537.3129 High mobility group protein HMG-I\HMG-Y OS=Homo sapiens OX=9606 GN=HMGA1 PE=1 SV=3 10 2096 - 2.38E+06 - - - -1.5961 - 3.211 0.544 - 521.1 1 2 0 -0.0026 16 0 0 0 1.32E+08 1.52E+08 - - - 7.5976 1 221125_WJC_METTL3_EV_vs_WT_F08.10399.10399.3 3.47E-14 27/72 R.VNLEESSGVENSPAGAR[166.11]PK[136.11].R "sp|Q8WVM8|SCFD1_HUMAN,tr|A0A7I2V4U2|A0A7I2V4U2_HUMAN,tr|A0A7I2V4B8|A0A7I2V4B8_HUMAN,tr|H0YIZ7|H0YIZ7_HUMAN,tr|A0A7I2V5Z4|A0A7I2V5Z4_HUMAN,tr|A0A7I2V3C9|A0A7I2V3C9_HUMAN,tr|B7Z5N7|B7Z5N7_HUMAN,tr|A0A7I2V5I2|A0A7I2V5I2_HUMAN,tr|A0A7I2V590|A0A7I2V590_HUMAN,tr|G3V5E2|G3V5E2_HUMAN,tr|A0A7I2V2U5|A0A7I2V2U5_HUMAN,tr|A0A7I2YQR2|A0A7I2YQR2_HUMAN,tr|A0A7I2V362|A0A7I2V362_HUMAN,tr|A0A7I2V448|A0A7I2V448_HUMAN,tr|A0A7I2V320|A0A7I2V320_HUMAN,tr|A0A7I2V534|A0A7I2V534_HUMAN,tr|A0A7I2V3G4|A0A7I2V3G4_HUMAN,tr|A0A7I2V3B4|A0A7I2V3B4_HUMAN,tr|A0A7I2V5H5|A0A7I2V5H5_HUMAN,tr|A0A7I2V4R0|A0A7I2V4R0_HUMAN,tr|A0A7I2V321|A0A7I2V321_HUMAN" 21 1957.9824 1.33 115019 10399 3 1957.977643 653.6681 Sec1 family domain-containing protein 1 OS=Homo sapiens OX=9606 GN=SCFD1 PE=1 SV=4 4.79 2096.1 - 3.14E+06 - - - -2.4311 - 4.559 0.71 - 986.9 1 2 0 -0.0048 19 0 0 0 8.66E+07 6.51E+07 - - - 10.1817 1 221125_WJC_METTL3_EV_vs_WT_F08.10400.10400.3 1.93E-10 21/52 R.DHAVVVGVYR[166.11]PPPK[136.11].V sp|P22087|FBRL_HUMAN 1 1550.8688 1.09 115020 10400 3 1550.868571 517.9635 rRNA 2'-O-methyltransferase fibrillarin OS=Homo sapiens OX=9606 GN=FBL PE=1 SV=2 8.6 2096.2 - 1.17E+06 - - - -0.1586 - 3.715 0.634 - 710 1 2 0 -0.0002 14 0 0 0 8.90E+07 8.18E+07 - - - 9.0961 1 221125_WJC_METTL3_EV_vs_WT_F08.10401.10401.2 4.99E-07 15/22 V.INETSQHHDDLE.- sp|P08670|VIME_HUMAN 1 1436.6168 - 115021 10401 2 1436.618236 719.3157 Vimentin OS=Homo sapiens OX=9606 GN=VIM PE=1 SV=4 4.52 2096.3 - 966189 - - - 0.9989 - 2.756 0.663 - 796.6 1 1 0 0.0014 12 0 0 0 - - - - - 6.6049 0.9997 221125_WJC_METTL3_EV_vs_WT_F08.10402.10402.2 2.30E-05 13/24 K.EFHLNESGDPSSK[136.11].S "sp|Q01105|SET_HUMAN,sp|P0DME0|SETLP_HUMAN,tr|A0A0C4DFV9|A0A0C4DFV9_HUMAN" 3 1453.6565 0.72 115022 10402 2 1453.653029 727.8355 Protein SET OS=Homo sapiens OX=9606 GN=SET PE=1 SV=3 4.65 2096.5 - 825404 - - - -2.3788 - 2.374 0.525 - 390.3 1 2 0 -0.0035 13 0 0 0 1.33E+07 1.85E+07 - - - 5.1365 1 221125_WJC_METTL3_EV_vs_WT_F08.10406.10406.3 5.99E-11 21/72 R.VNLEESSGVENSPAGARPK.R "sp|Q8WVM8|SCFD1_HUMAN,tr|A0A7I2V4U2|A0A7I2V4U2_HUMAN,tr|A0A7I2V4B8|A0A7I2V4B8_HUMAN,tr|H0YIZ7|H0YIZ7_HUMAN,tr|A0A7I2V5Z4|A0A7I2V5Z4_HUMAN,tr|A0A7I2V3C9|A0A7I2V3C9_HUMAN,tr|B7Z5N7|B7Z5N7_HUMAN,tr|A0A7I2V5I2|A0A7I2V5I2_HUMAN,tr|A0A7I2V590|A0A7I2V590_HUMAN,tr|G3V5E2|G3V5E2_HUMAN,tr|A0A7I2V2U5|A0A7I2V2U5_HUMAN,tr|A0A7I2YQR2|A0A7I2YQR2_HUMAN,tr|A0A7I2V362|A0A7I2V362_HUMAN,tr|A0A7I2V448|A0A7I2V448_HUMAN,tr|A0A7I2V320|A0A7I2V320_HUMAN,tr|A0A7I2V534|A0A7I2V534_HUMAN,tr|A0A7I2V3G4|A0A7I2V3G4_HUMAN,tr|A0A7I2V3B4|A0A7I2V3B4_HUMAN,tr|A0A7I2V5H5|A0A7I2V5H5_HUMAN,tr|A0A7I2V4R0|A0A7I2V4R0_HUMAN,tr|A0A7I2V321|A0A7I2V321_HUMAN" 21 1939.9599 1.33 115024 10406 3 1939.958274 647.6606 Sec1 family domain-containing protein 1 OS=Homo sapiens OX=9606 GN=SCFD1 PE=1 SV=4 4.79 2097 - 3.73E+06 - - - -0.8552 - 3.961 0.639 - 529.8 1 2 0 -0.0017 19 0 0 0 8.66E+07 6.51E+07 - - - 9.0455 1 221125_WJC_METTL3_EV_vs_WT_F08.10407.10407.3 1.34E-07 15/48 K.RTAAENEFVTLKK.D "sp|P48668|K2C6C_HUMAN,sp|P12035|K2C3_HUMAN,sp|P04259|K2C6B_HUMAN,sp|P02538|K2C6A_HUMAN" 4 1505.8202 3.89 115025 10407 3 1505.819241 502.9473 "Keratin, type II cytoskeletal 6C OS=Homo sapiens OX=9606 GN=KRT6C PE=1 SV=3" 8.59 2097.1 - 2.08E+06 - - - -0.6315 - 2.936 0.495 - 385 1 2 0 -0.001 13 0 0 0 4.18E+07 1.08E+07 - - - 6.9787 1 221125_WJC_METTL3_EV_vs_WT_F08.10408.10408.3 4.36E-10 22/52 R.DHAVVVGVYRPPPK.V sp|P22087|FBRL_HUMAN 1 1532.8463 1.09 115026 10408 3 1532.846216 511.9561 rRNA 2'-O-methyltransferase fibrillarin OS=Homo sapiens OX=9606 GN=FBL PE=1 SV=2 8.6 2097.2 - 1.26E+06 - - - -0.0855 - 3.666 0.54 - 796.4 1 2 0 -0.0001 14 0 0 0 9.61E+07 8.84E+07 - - - 8.0128 0.9971 221125_WJC_METTL3_EV_vs_WT_F08.10411.10411.4 0.0136 14/84 R.TSVIQGIHTDHNTLK[136.11].L sp|Q5U5X0|LYRM7_HUMAN 1 1670.8831 1.4 115029 10411 4 1670.880358 418.7281 Complex III assembly factor LYRM7 OS=Homo sapiens OX=9606 GN=LYRM7 PE=1 SV=1 6.61 2097.6 - 655874 - - - -1.6608 - 2.409 0.246 - 136.1 1 2 0 -0.0028 15 0 0 0 1.68E+08 1.20E+08 - - - 1.681 0.9997 221125_WJC_METTL3_EV_vs_WT_F08.10414.10414.3 0.00196 Dec-48 K.EFHLNESGDPSSK[136.11].S "sp|Q01105|SET_HUMAN,sp|P0DME0|SETLP_HUMAN,tr|A0A0C4DFV9|A0A0C4DFV9_HUMAN" 3 1453.6565 0.99 115030 10414 3 1453.653205 485.5594 Protein SET OS=Homo sapiens OX=9606 GN=SET PE=1 SV=3 4.65 2098 - 7.13E+06 - - - -2.2578 - 2.082 0.4 - 185.6 1 2 0 -0.0033 13 0 0 0 1.52E+08 1.54E+08 - - - 4.987 1 221125_WJC_METTL3_EV_vs_WT_F08.10415.10415.3 0.0024 20/52 K.C[160.03]LDENLEDASQC[160.03]KK.L sp|Q5JTJ3|COA6_HUMAN 1 1708.7396 0.69 115031 10415 3 1708.736881 570.5872 Cytochrome c oxidase assembly factor 6 homolog OS=Homo sapiens OX=9606 GN=COA6 PE=1 SV=1 4.32 2098.1 - 2.58E+06 - - - -1.6117 - 3.269 0.613 - 533.5 1 2 0 -0.0028 14 0 0 0 5.44E+07 7.91E+07 - - - 8.5214 0.9998 221125_WJC_METTL3_EV_vs_WT_F08.10418.10418.4 2.39E-05 15/78 R.DHAVVVGVYRPPPK.V sp|P22087|FBRL_HUMAN 1 1532.8463 0.84 115033 10418 4 1532.84298 384.2189 rRNA 2'-O-methyltransferase fibrillarin OS=Homo sapiens OX=9606 GN=FBL PE=1 SV=2 8.6 2098.3 - 532730 - - - -2.1966 - 2.617 0.419 - 261.5 1 2 0 -0.0034 14 0 0 0 2.57E+07 3.08E+07 - - - 3.2222 0.9997 221125_WJC_METTL3_EV_vs_WT_F08.10425.10425.4 0.0392 16/78 R.DHAVVVGVYR[166.11]PPPK[136.11].V sp|P22087|FBRL_HUMAN 1 1550.8688 0.88 115038 10425 4 1550.863992 388.7245 rRNA 2'-O-methyltransferase fibrillarin OS=Homo sapiens OX=9606 GN=FBL PE=1 SV=2 8.6 2099 - 847474 - - - -3.1112 - 2.949 0.411 - 301.8 1 2 0 -0.0048 14 0 0 0 2.54E+07 2.89E+07 - - - 3.1956 1 221125_WJC_METTL3_EV_vs_WT_F08.10428.10428.3 9.93E-12 19/60 K.R[166.11]PELLTHSTTEVTQPR[166.11].T "sp|P78347|GTF2I_HUMAN,tr|A0A494C0Q7|A0A494C0Q7_HUMAN,tr|A0A494C1K3|A0A494C1K3_HUMAN" 3 1883.9968 1.49 115039 10428 3 1883.99499 629.0062 General transcription factor II-I OS=Homo sapiens OX=9606 GN=GTF2I PE=1 SV=2 6.76 2099.4 - 7.67E+06 - - - -0.9687 - 4.048 0.588 - 638.1 1 2 0 -0.0018 16 0 0 0 4.81E+08 3.22E+08 - - - 8.6828 1 221125_WJC_METTL3_EV_vs_WT_F08.10431.10431.2 1.27E-07 13/24 K.EFHLNESGDPSSK.S "sp|Q01105|SET_HUMAN,sp|P0DME0|SETLP_HUMAN,tr|A0A0C4DFV9|A0A0C4DFV9_HUMAN" 3 1445.6423 0.72 115042 10431 2 1445.639975 723.8284 Protein SET OS=Homo sapiens OX=9606 GN=SET PE=1 SV=3 4.65 2099.8 - 412109 - - - -1.5993 - 2.668 0.611 - 441.1 1 2 0 -0.0023 13 0 0 0 1.33E+07 1.85E+07 - - - 6.0717 1 221125_WJC_METTL3_EV_vs_WT_F08.10433.10433.2 9.28E-11 13/36 K.EDGSEVGVGGAQVTGSNTR[166.11].K "sp|Q13618|CUL3_HUMAN,tr|H7C399|H7C399_HUMAN,tr|A0A087WTG3|A0A087WTG3_HUMAN" 3 1828.8427 2.62 115044 10433 2 1828.841326 915.4286 Cullin-3 OS=Homo sapiens OX=9606 GN=CUL3 PE=1 SV=2 4.14 2100 - 195645 - - - -0.7338 - 2.613 0.717 - 359.6 1 2 0 -0.0013 19 0 0 0 1.38E+07 5.25E+06 - - - 6.6978 1 221125_WJC_METTL3_EV_vs_WT_F08.10438.10438.4 1.42E-05 15/84 R.TSVIQGIHTDHNTLK.L sp|Q5U5X0|LYRM7_HUMAN 1 1662.8689 1.41 115047 10438 4 1662.868943 416.7245 Complex III assembly factor LYRM7 OS=Homo sapiens OX=9606 GN=LYRM7 PE=1 SV=1 6.61 2100.5 - 2.72E+06 - - - 0.006 - 2.892 0.471 - 181.3 1 2 0 0 15 0 0 0 1.69E+08 1.20E+08 - - - 3.7056 0.9974 221125_WJC_METTL3_EV_vs_WT_F08.10440.10440.3 0.0106 Sep-48 K.QKIHPTSVISGYR.L "sp|P17987|TCPA_HUMAN,tr|F5H136|F5H136_HUMAN,tr|E7ERF2|E7ERF2_HUMAN,tr|F5H676|F5H676_HUMAN" 4 1484.81 0.41 115049 10440 3 1484.809509 495.9439 T-complex protein 1 subunit alpha OS=Homo sapiens OX=9606 GN=TCP1 PE=1 SV=1 9.99 2100.7 - 850084 - - - -0.3051 - 2.163 0.278 - 131.1 1 2 1 -0.0005 13 0 0 0 4.08E+07 1.00E+08 - - - 3.7311 0.9993 221125_WJC_METTL3_EV_vs_WT_F08.10441.10441.3 0.000546 Oct-32 R.MDYEDDRLR.D "sp|P43243|MATR3_HUMAN,tr|A8MXP9|A8MXP9_HUMAN,tr|D6R991|D6R991_HUMAN,tr|A0A0R4J2E8|A0A0R4J2E8_HUMAN,tr|D6REM6|D6REM6_HUMAN" 5 1211.5241 1.22 115050 10441 3 1211.522714 404.8486 Matrin-3 OS=Homo sapiens OX=9606 GN=MATR3 PE=1 SV=2 4.23 2100.9 - 656358 - - - -1.1325 - 1.686 0.428 - 263.5 1 2 1 -0.0014 9 0 0 0 1.37E+07 1.13E+07 - - - 4.8857 1 221125_WJC_METTL3_EV_vs_WT_F08.10446.10446.3 2.91E-08 16/56 R.TSVIQGIHTDHNTLK[136.11].L sp|Q5U5X0|LYRM7_HUMAN 1 1670.8831 1.41 115053 10446 3 1670.883579 557.9683 Complex III assembly factor LYRM7 OS=Homo sapiens OX=9606 GN=LYRM7 PE=1 SV=1 6.61 2101.5 - 3.24E+06 - - - 0.2669 - 3.1 0.521 - 341 1 2 0 0.0004 15 0 0 0 1.94E+08 1.37E+08 - - - 7.3008 0.9997 221125_WJC_METTL3_EV_vs_WT_F08.10448.10448.4 0.000555 Nov-84 K.TR[166.11]DDEPVC[160.03]GR[166.11]PLGIR[166.11].A "sp|Q9HDC9|APMAP_HUMAN,tr|H0Y512|H0Y512_HUMAN" 2 1769.8985 1.79 115055 10448 4 1769.895493 443.4819 Adipocyte plasma membrane-associated protein OS=Homo sapiens OX=9606 GN=APMAP PE=1 SV=2 5.79 2101.7 - 1.12E+06 - - - -1.7052 - 2.219 0.464 - 87.9 1 2 1 -0.003 15 0 0 0 8.85E+07 4.93E+07 - - - 3.549 1 221125_WJC_METTL3_EV_vs_WT_F08.10450.10450.2 1.55E-09 16/32 R.SDSPVPTAPTSGGPK[136.11]PS.T "sp|Q86U44|MTA70_HUMAN,tr|B4E349|B4E349_HUMAN,tr|F5H6D8|F5H6D8_HUMAN,tr|B4DTN4|B4DTN4_HUMAN" 4 1588.7824 0.02 115057 10450 2 1588.780303 795.3985 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 5.55 2102 - 697434 - - - -1.3299 - 2.745 0.647 - 486.4 1 1 0 -0.0021 17 0 0 0 1.87E+08 8.08E+09 - - - 6.3017 0.9881 221125_WJC_METTL3_EV_vs_WT_F08.10454.10454.4 0.00873 Oct-84 K.TRDDEPVC[160.03]GRPLGIR.A "sp|Q9HDC9|APMAP_HUMAN,tr|H0Y512|H0Y512_HUMAN" 2 1739.8737 1.81 115059 10454 4 1739.871033 435.9757 Adipocyte plasma membrane-associated protein OS=Homo sapiens OX=9606 GN=APMAP PE=1 SV=2 5.79 2102.4 - 2.13E+06 - - - -1.5334 - 1.747 0.254 - 79.5 1 2 1 -0.0027 15 0 0 0 8.98E+07 4.95E+07 - - - 1.6357 0.9999 221125_WJC_METTL3_EV_vs_WT_F08.10459.10459.3 4.24E-07 19/56 K.TRDDEPVC[160.03]GRPLGIR.A "sp|Q9HDC9|APMAP_HUMAN,tr|H0Y512|H0Y512_HUMAN" 2 1739.8737 1.25 115062 10459 3 1739.873926 580.9652 Adipocyte plasma membrane-associated protein OS=Homo sapiens OX=9606 GN=APMAP PE=1 SV=2 5.79 2103 - 809705 - - - 0.1293 - 2.965 0.489 - 241 1 2 1 0.0002 15 0 0 0 4.39E+07 3.50E+07 - - - 6.8279 1 221125_WJC_METTL3_EV_vs_WT_F08.10464.10464.3 6.47E-08 18/60 R.C[160.03]VTDPAYEDVNNC[160.03]HER.A sp|Q9HCS7|SYF1_HUMAN 1 1977.7945 1.72 115065 10464 3 1977.793425 660.2721 Pre-mRNA-splicing factor SYF1 OS=Homo sapiens OX=9606 GN=XAB2 PE=1 SV=2 4.31 2103.7 - 625718 - - - -0.5562 - 3.141 0.721 - 253.6 1 2 0 -0.0011 16 0 0 0 1.64E+07 9.52E+06 - - - 9.5149 0.9995 221125_WJC_METTL3_EV_vs_WT_F08.10465.10465.4 1.17E-05 18/84 K.DTGKTPVEPEVAIHR.L "sp|P60866|RS20_HUMAN,tr|E5RJX2|E5RJX2_HUMAN,tr|E5RIP1|E5RIP1_HUMAN" 3 1647.858 0.75 115066 10465 4 1647.86165 412.9718 40S ribosomal protein S20 OS=Homo sapiens OX=9606 GN=RPS20 PE=1 SV=1 5.45 2103.8 - 808770 - - - 2.1944 - 2.848 0.441 - 223.2 1 2 1 0.0036 15 0 0 0 3.84E+07 5.14E+07 - - - 3.438 0.9999 221125_WJC_METTL3_EV_vs_WT_F08.10466.10466.3 5.40E-05 Dec-44 R.LNYEHDNISLK[136.11]R[166.11].V "sp|Q969X6|UTP4_HUMAN,tr|H3BRM8|H3BRM8_HUMAN,tr|H3BSH7|H3BSH7_HUMAN,tr|A0A0J9YWK2|A0A0J9YWK2_HUMAN,tr|A0A0J9YWM9|A0A0J9YWM9_HUMAN" 5 1518.791 0.4 115067 10466 3 1518.788871 507.2709 U3 small nucleolar RNA-associated protein 4 homolog OS=Homo sapiens OX=9606 GN=UTP4 PE=1 SV=1 6.75 2103.9 - 602770 - - - -1.3761 - 2.312 0.399 - 216.4 1 2 0 -0.0021 12 0 0 0 3.88E+06 9.58E+06 - - - 5.311 0.9968 221125_WJC_METTL3_EV_vs_WT_F08.10472.10472.3 0.000784 Oct-32 K.YK[136.11]DDPVDLR[166.11].L "sp|Q9Y2W1|TR150_HUMAN,tr|A0A3B3ITZ9|A0A3B3ITZ9_HUMAN" 2 1137.5785 0.001 115071 10472 3 1137.577538 380.2001 Thyroid hormone receptor-associated protein 3 OS=Homo sapiens OX=9606 GN=THRAP3 PE=1 SV=2 4.43 2104.6 - 1.09E+06 - - - -0.8527 - 1.585 0.327 - 158.5 1 2 1 -0.001 9 0 0 0 0.00E+00 2.63E+07 - - - 3.5736 1 221125_WJC_METTL3_EV_vs_WT_F08.10473.10473.3 5.72E-07 15/80 R.GLDEEATPGTPGDPAR[166.11]PPASK[136.11].A sp|Q7Z7A3|CTU1_HUMAN 1 2080.0192 1.53 115072 10473 3 2080.017195 694.347 Cytoplasmic tRNA 2-thiolation protein 1 OS=Homo sapiens OX=9606 GN=CTU1 PE=1 SV=1 4.32 2104.7 - 739314 - - - -0.9558 - 2.652 0.55 - 187.9 1 2 0 -0.002 21 0 0 0 1.43E+07 9.39E+06 - - - 7.0097 0.9992 221125_WJC_METTL3_EV_vs_WT_F08.10485.10485.3 1.46E-05 18/56 K.TR[166.11]DDEPVC[160.03]GR[166.11]PLGIR[166.11].A "sp|Q9HDC9|APMAP_HUMAN,tr|H0Y512|H0Y512_HUMAN" 2 1769.8985 1.25 115081 10485 3 1769.896563 590.9734 Adipocyte plasma membrane-associated protein OS=Homo sapiens OX=9606 GN=APMAP PE=1 SV=2 5.79 2106.2 - 1.09E+06 - - - -1.1006 - 2.261 0.363 - 221.9 1 2 1 -0.0019 15 0 0 0 4.39E+07 3.50E+07 - - - 4.7153 1 221125_WJC_METTL3_EV_vs_WT_F08.10486.10486.2 1.01E-12 14/28 K.TTDDTTTDNYIAQGK[136.11].R sp|Q7Z2T5|TRM1L_HUMAN 1 1650.7464 0.24 115082 10486 2 1650.745117 826.3805 TRMT1-like protein OS=Homo sapiens OX=9606 GN=TRMT1L PE=1 SV=2 3.93 2106.3 - 725095 - - - -0.7924 - 3.091 0.703 - 626.7 1 2 0 -0.0013 15 0 0 0 4.37E+06 1.79E+07 - - - 7.0074 0.993 221125_WJC_METTL3_EV_vs_WT_F08.10493.10493.2 0.00258 16-Sep R.TLLEGEESR.M sp|P04264|K2C1_HUMAN 1 1032.5088 6.01 115085 10493 2 1032.5041 517.2617 "Keratin, type II cytoskeletal 1 OS=Homo sapiens OX=9606 GN=KRT1 PE=1 SV=6" 4.25 2107.1 - 1.56E+06 - - - -4.5075 - 1.545 0.363 - 259.7 1 2 0 -0.0047 9 0 0 0 4.48E+07 7.45E+06 - - - 2.9792 1 221125_WJC_METTL3_EV_vs_WT_F08.10502.10502.3 3.05E-07 23/72 R.AASAGQEPLHNEELAGAGR.V "sp|Q96HY6|DDRGK_HUMAN,tr|A0A0A0MRX2|A0A0A0MRX2_HUMAN" 2 1876.9028 1.3 115089 10502 3 1876.900151 626.6415 DDRGK domain-containing protein 1 OS=Homo sapiens OX=9606 GN=DDRGK1 PE=1 SV=2 4.75 2108.2 - 1.12E+06 - - - -1.3863 - 4.018 0.579 - 875.9 1 2 0 -0.0026 19 0 0 0 6.33E+07 4.88E+07 - - - 8.4114 1 221125_WJC_METTL3_EV_vs_WT_F08.10505.10505.3 6.66E-10 18/52 K.TGTITTFEHAHNMR[166.11].V sp|P13639|EF2_HUMAN 1 1624.7655 0.44 115092 10505 3 1624.760804 542.5958 Elongation factor 2 OS=Homo sapiens OX=9606 GN=EEF2 PE=1 SV=4 6.61 2108.6 - 804928 - - - -2.9173 - 3.799 0.563 - 850.1 1 2 0 -0.0047 14 0 0 0 9.30E+07 2.13E+08 - - - 8.3627 1 221125_WJC_METTL3_EV_vs_WT_F08.10512.10512.4 5.36E-07 22/78 K.TGTITTFEHAHNMR[166.11].V sp|P13639|EF2_HUMAN 1 1624.7655 0.41 115097 10512 4 1624.764345 407.1987 Elongation factor 2 OS=Homo sapiens OX=9606 GN=EEF2 PE=1 SV=4 6.61 2109.4 - 1.50E+06 - - - -0.738 - 3.221 0.543 - 611.4 1 2 0 -0.0012 14 0 0 0 6.78E+07 1.64E+08 - - - 4.3776 0.9941 221125_WJC_METTL3_EV_vs_WT_F08.10519.10519.3 2.04E-05 17/56 R.TQSVTSPENSHIMPH.S sp|Q9UI36|DACH1_HUMAN 1 1663.7624 - 115100 10519 3 1663.758702 555.5947 Dachshund homolog 1 OS=Homo sapiens OX=9606 GN=DACH1 PE=1 SV=4 5.92 2110.3 - 4.37E+06 - - - -2.2341 - 3.139 0.462 - 417.9 1 1 0 -0.0037 15 0 0 0 - - - - - 6.6747 1 221125_WJC_METTL3_EV_vs_WT_F08.10521.10521.3 8.04E-09 21/52 K.TGTITTFEHAHNMR.V sp|P13639|EF2_HUMAN 1 1614.7573 0.44 115102 10521 3 1614.753124 539.2597 Elongation factor 2 OS=Homo sapiens OX=9606 GN=EEF2 PE=1 SV=4 6.61 2110.6 - 1.95E+06 - - - -2.57 - 3.469 0.558 - 630.9 1 2 0 -0.0042 14 0 0 0 9.30E+07 2.13E+08 - - - 8.0656 0.9929 221125_WJC_METTL3_EV_vs_WT_F08.10532.10532.4 895 3/102 R.GDEDDEESDDETDGEDGE.G sp|Q96K62|ZBT45_HUMAN 1 1956.5988 - 115107 10532 4 1956.596246 490.157 Zinc finger and BTB domain-containing protein 45 OS=Homo sapiens OX=9606 GN=ZBTB45 PE=1 SV=1 3.11 2112 - 3.31E+06 - - - -1.3171 - 0.245 0.549 - 1.6 1 1 0 -0.0026 18 0 0 0 - - - - - 3.522 0.9997 221125_WJC_METTL3_EV_vs_WT_F08.10537.10537.3 0.000855 13/44 K.VC[160.03]EIHFHEINNK.M "sp|O43347|MSI1H_HUMAN,sp|Q96DH6|MSI2H_HUMAN,tr|B4DHE8|B4DHE8_HUMAN,tr|A0A6Q8PGD8|A0A6Q8PGD8_HUMAN,tr|H0YHB7|H0YHB7_HUMAN,tr|A0A6Q8PF05|A0A6Q8PF05_HUMAN,tr|B4DM51|B4DM51_HUMAN" 7 1538.73 1.49 115110 10537 3 1538.726044 513.9173 RNA-binding protein Musashi homolog 1 OS=Homo sapiens OX=9606 GN=MSI1 PE=1 SV=1 6 2112.6 - 2.04E+06 - - - -2.569 - 2.247 0.38 - 207 1 2 0 -0.004 12 0 0 0 5.74E+08 3.87E+08 - - - 5.0196 1 221125_WJC_METTL3_EV_vs_WT_F08.10540.10540.4 3.74E-07 17/78 K.TGTITTFEHAHNMR.V sp|P13639|EF2_HUMAN 1 1614.7573 0.42 115111 10540 4 1614.754232 404.6966 Elongation factor 2 OS=Homo sapiens OX=9606 GN=EEF2 PE=1 SV=4 6.61 2113 - 3.58E+06 - - - -1.8839 - 3.264 0.579 - 374 1 2 0 -0.003 14 0 0 0 6.89E+07 1.65E+08 - - - 4.6953 0.9997 221125_WJC_METTL3_EV_vs_WT_F08.10543.10543.4 7.29E-05 14/66 K.VC[160.03]EIHFHEINNK.M "sp|O43347|MSI1H_HUMAN,sp|Q96DH6|MSI2H_HUMAN,tr|B4DHE8|B4DHE8_HUMAN,tr|A0A6Q8PGD8|A0A6Q8PGD8_HUMAN,tr|H0YHB7|H0YHB7_HUMAN,tr|A0A6Q8PF05|A0A6Q8PF05_HUMAN,tr|B4DM51|B4DM51_HUMAN" 7 1538.73 1.38 115114 10543 4 1538.723669 385.6898 RNA-binding protein Musashi homolog 1 OS=Homo sapiens OX=9606 GN=MSI1 PE=1 SV=1 6 2113.3 - 2.18E+06 - - - -4.1125 - 2.486 0.485 - 153.5 1 2 0 -0.0063 12 0 0 0 4.75E+08 3.45E+08 - - - 3.7903 0.9986 221125_WJC_METTL3_EV_vs_WT_F08.10550.10550.3 3.48E-05 17/44 K.VC[160.03]EIHFHEINNK[136.11].M "sp|O43347|MSI1H_HUMAN,sp|Q96DH6|MSI2H_HUMAN,tr|B4DHE8|B4DHE8_HUMAN,tr|A0A6Q8PGD8|A0A6Q8PGD8_HUMAN,tr|H0YHB7|H0YHB7_HUMAN,tr|A0A6Q8PF05|A0A6Q8PF05_HUMAN,tr|B4DM51|B4DM51_HUMAN" 7 1546.7442 1.49 115118 10550 3 1546.737856 516.5887 RNA-binding protein Musashi homolog 1 OS=Homo sapiens OX=9606 GN=MSI1 PE=1 SV=1 6 2114.1 - 3.65E+06 - - - -4.0996 - 2.705 0.308 - 475.1 1 2 0 -0.0063 12 0 0 0 5.74E+08 3.87E+08 - - - 4.7304 1 221125_WJC_METTL3_EV_vs_WT_F08.10551.10551.3 2.68E-09 18/52 K.ITESVAETAQTIKK.S sp|Q96A49|SYAP1_HUMAN 1 1517.8301 0.56 115119 10551 3 1517.831329 506.9506 Synapse-associated protein 1 OS=Homo sapiens OX=9606 GN=SYAP1 PE=1 SV=1 6.14 2114.2 - 2.20E+06 - - - 0.8176 - 3.035 0.539 - 587.7 1 2 0 0.0012 14 0 0 0 4.47E+07 7.96E+07 - - - 7.4994 0.9917 221125_WJC_METTL3_EV_vs_WT_F08.10552.10552.3 1.86E-08 18/64 R.SDSPVPTAPTSGGPK[136.11]PS.T "sp|Q86U44|MTA70_HUMAN,tr|B4E349|B4E349_HUMAN,tr|F5H6D8|F5H6D8_HUMAN,tr|B4DTN4|B4DTN4_HUMAN" 4 1588.7824 0 115120 10552 3 1588.777183 530.6014 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 5.55 2114.3 - 2.10E+06 - - - -3.2937 - 3.035 0.534 - 368.6 1 1 0 -0.0052 17 0 0 0 3.75E+05 1.36E+08 - - - 7.2969 0.9985 221125_WJC_METTL3_EV_vs_WT_F08.10560.10560.3 3.53E-06 13/56 K.AENK[136.11]GNDPNVSLVPK[136.11].D sp|P48634|PRC2A_HUMAN 1 1596.8442 1.8 115125 10560 3 1596.840381 533.2887 Protein PRRC2A OS=Homo sapiens OX=9606 GN=PRRC2A PE=1 SV=3 6.11 2115.3 - 1.37E+06 - - - -2.4135 - 2.296 0.38 - 149.8 1 2 1 -0.0039 15 0 0 0 9.97E+07 5.55E+07 - - - 4.9444 1 221125_WJC_METTL3_EV_vs_WT_F08.10561.10561.2 2.48E-09 15/32 R.SDSPVPTAPTSGGPKPS.T "sp|Q86U44|MTA70_HUMAN,tr|B4E349|B4E349_HUMAN,tr|F5H6D8|F5H6D8_HUMAN,tr|B4DTN4|B4DTN4_HUMAN" 4 1580.7682 0.02 115126 10561 2 1580.762862 791.3914 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 5.55 2115.4 - 2.27E+06 - - - -3.387 - 2.871 0.67 - 406.7 1 1 0 -0.0054 17 0 0 0 1.87E+08 7.91E+09 - - - 6.5809 0.9999 221125_WJC_METTL3_EV_vs_WT_F08.10569.10569.3 7.70E-10 15/56 K.AENKGNDPNVSLVPK.D sp|P48634|PRC2A_HUMAN 1 1580.8158 1.8 115129 10569 3 1580.817118 527.9459 Protein PRRC2A OS=Homo sapiens OX=9606 GN=PRRC2A PE=1 SV=3 6.11 2116.4 - 1.39E+06 - - - 0.8116 - 2.881 0.588 - 195 1 2 1 0.0013 15 0 0 0 9.97E+07 5.55E+07 - - - 7.8563 1 221125_WJC_METTL3_EV_vs_WT_F08.10570.10570.2 1.59E-10 14/32 V.FAGTNTGPNNSNTTFQK[136.11].R "sp|Q9NYF8|BCLF1_HUMAN,tr|H0YF14|H0YF14_HUMAN" 2 1805.8424 0.19 115130 10570 2 1805.845787 903.9285 Bcl-2-associated transcription factor 1 OS=Homo sapiens OX=9606 GN=BCLAF1 PE=1 SV=2 8.75 2116.6 - 627305 - - - 1.8806 - 3.219 0.675 - 504.5 1 1 0 0.0034 17 0 0 0 3.94E+06 2.07E+07 - - - 6.8997 1 221125_WJC_METTL3_EV_vs_WT_F08.10572.10572.3 1.37E-07 21/72 R.YLTQVATGQPHEGSSYSSR.K sp|Q9P086|MED11_HUMAN 1 2066.9657 2 115132 10572 3 2066.969779 689.9959 Mediator of RNA polymerase II transcription subunit 11 OS=Homo sapiens OX=9606 GN=MED11 PE=1 SV=2 6.75 2116.8 - 1.13E+06 - - - 1.9507 - 3.657 0.579 - 544.1 1 2 0 0.004 19 0 0 0 3.71E+07 1.86E+07 - - - 8.1798 1 221125_WJC_METTL3_EV_vs_WT_F08.10581.10581.3 3.94E-05 17/52 K.EQIVPKPEEEVAQK.K "sp|P18621|RL17_HUMAN,tr|J3QLC8|J3QLC8_HUMAN,tr|J3QQT2|J3QQT2_HUMAN,tr|A0A0A0MRF8|A0A0A0MRF8_HUMAN,tr|J3KRX5|J3KRX5_HUMAN,tr|A0A087WXM6|A0A087WXM6_HUMAN,tr|A0A0A6YYL6|A0A0A6YYL6_HUMAN" 7 1622.8516 1.06 115137 10581 3 1622.850343 541.9578 60S ribosomal protein L17 OS=Homo sapiens OX=9606 GN=RPL17 PE=1 SV=3 4.49 2117.9 - 2.11E+06 - - - -0.745 - 2.557 0.467 - 270.3 1 2 0 -0.0012 14 0 0 0 2.51E+08 2.38E+08 - - - 6.2412 0.9999 221125_WJC_METTL3_EV_vs_WT_F08.10584.10584.4 6.09E-06 13/66 K.VC[160.03]EIHFHEINNK[136.11].M "sp|O43347|MSI1H_HUMAN,sp|Q96DH6|MSI2H_HUMAN,tr|B4DHE8|B4DHE8_HUMAN,tr|A0A6Q8PGD8|A0A6Q8PGD8_HUMAN,tr|H0YHB7|H0YHB7_HUMAN,tr|A0A6Q8PF05|A0A6Q8PF05_HUMAN,tr|B4DM51|B4DM51_HUMAN" 7 1546.7442 1.38 115138 10584 4 1546.739835 387.6933 RNA-binding protein Musashi homolog 1 OS=Homo sapiens OX=9606 GN=MSI1 PE=1 SV=1 6 2118.3 - 1.40E+07 - - - -2.8201 - 2.453 0.494 - 149.4 1 2 0 -0.0044 12 0 0 0 4.76E+08 3.45E+08 - - - 3.8641 0.993 221125_WJC_METTL3_EV_vs_WT_F08.10590.10590.3 0.0185 Oct-36 K.YK[136.11]DAIHFYNK[136.11].S sp|P31948|STIP1_HUMAN 1 1313.6739 1.27 115142 10590 3 1313.671586 438.8986 Stress-induced-phosphoprotein 1 OS=Homo sapiens OX=9606 GN=STIP1 PE=1 SV=1 8.44 2119.1 - 1.13E+06 - - - -1.7782 - 1.913 0.259 - 68.8 1 2 1 -0.0023 10 0 0 0 6.30E+07 4.97E+07 - - - 3.3214 0.999 221125_WJC_METTL3_EV_vs_WT_F08.10596.10596.3 0.0171 Dec-48 R.EDLQLDK[136.11]PASGVK[136.11].E "sp|P78347|GTF2I_HUMAN,tr|A0A494C0Q7|A0A494C0Q7_HUMAN,tr|A0A494C1K3|A0A494C1K3_HUMAN" 3 1414.7639 2.14 115146 10596 3 1414.76052 472.5952 General transcription factor II-I OS=Homo sapiens OX=9606 GN=GTF2I PE=1 SV=2 4.56 2119.8 - 696512 - - - -2.3601 - 2.055 0.307 - 154.9 1 2 0 -0.0033 13 0 0 0 1.67E+07 7.83E+06 - - - 3.9147 1 221125_WJC_METTL3_EV_vs_WT_F08.10600.10600.3 3.22E-08 22/68 K.LPNQTHPDVPVGDESQAR[166.11].V "sp|Q9NP81|SYSM_HUMAN,tr|M0R2C6|M0R2C6_HUMAN,tr|M0QWZ7|M0QWZ7_HUMAN,tr|B4DJM9|B4DJM9_HUMAN" 4 1968.9529 1.1 115148 10600 3 1968.95491 657.3249 "Serine--tRNA ligase, mitochondrial OS=Homo sapiens OX=9606 GN=SARS2 PE=1 SV=1" 4.54 2120.3 - 1.44E+06 - - - 1.0274 - 3.662 0.566 - 572.8 1 2 0 0.002 18 0 0 0 2.20E+07 2.00E+07 - - - 8.082 1 221125_WJC_METTL3_EV_vs_WT_F08.10604.10604.2 6.86E-11 22-Dec K.VC[160.03]EIHFHEINNK.M "sp|O43347|MSI1H_HUMAN,sp|Q96DH6|MSI2H_HUMAN,tr|B4DHE8|B4DHE8_HUMAN,tr|A0A6Q8PGD8|A0A6Q8PGD8_HUMAN,tr|H0YHB7|H0YHB7_HUMAN,tr|A0A6Q8PF05|A0A6Q8PF05_HUMAN,tr|B4DM51|B4DM51_HUMAN" 7 1538.73 2.56 115150 10604 2 1538.727169 770.3723 RNA-binding protein Musashi homolog 1 OS=Homo sapiens OX=9606 GN=MSI1 PE=1 SV=1 6 2120.8 - 753851 - - - -1.8379 - 3.278 0.709 - 598.9 1 2 0 -0.0028 12 0 0 0 2.20E+07 8.61E+06 - - - 7.4006 0.9997 221125_WJC_METTL3_EV_vs_WT_F08.10605.10605.3 8.86E-09 13/60 K.ATAGDTHLGGEDFDNR[166.11].L "sp|P48741|HSP77_HUMAN,sp|P0DMV8|HS71A_HUMAN,sp|P34931|HS71L_HUMAN,sp|P0DMV9|HS71B_HUMAN,sp|P17066|HSP76_HUMAN,tr|Q53FA3|Q53FA3_HUMAN,tr|V9GZ37|V9GZ37_HUMAN,tr|A0A0G2JIW1|A0A0G2JIW1_HUMAN" 8 1684.7317 0.13 115151 10605 3 1684.725323 562.5845 Putative heat shock 70 kDa protein 7 OS=Homo sapiens OX=9606 GN=HSPA7 PE=5 SV=2 4.22 2121 - 842885 - - - -3.762 - 2.652 0.455 - 173.7 1 2 0 -0.0063 16 0 0 0 1.66E+07 1.28E+08 - - - 6.1136 1 221125_WJC_METTL3_EV_vs_WT_F08.10606.10606.4 8.52E-06 21/78 R.K[136.11]GVAINMVTEEDK[136.11]R[166.11].T sp|P60842|IF4A1_HUMAN 1 1614.861 0.89 115152 10606 4 1614.859284 404.7225 Eukaryotic initiation factor 4A-I OS=Homo sapiens OX=9606 GN=EIF4A1 PE=1 SV=1 6.18 2121.1 - 715051 - - - -1.0385 - 3.373 0.519 - 578.8 1 2 0 -0.0017 14 0 0 0 3.95E+07 4.43E+07 - - - 4.1854 1 221125_WJC_METTL3_EV_vs_WT_F08.10609.10609.3 1.16E-05 21/52 R.K[136.11]GVAINMVTEEDK[136.11]R[166.11].T sp|P60842|IF4A1_HUMAN 1 1614.861 0.85 115153 10609 3 1614.860846 539.2943 Eukaryotic initiation factor 4A-I OS=Homo sapiens OX=9606 GN=EIF4A1 PE=1 SV=1 6.18 2121.5 - 1.65E+06 - - - -0.0712 - 3.743 0.548 - 726.4 1 2 0 -0.0001 14 0 0 0 1.41E+08 1.67E+08 - - - 8.1573 1 221125_WJC_METTL3_EV_vs_WT_F08.10611.10611.3 1.92E-12 21/60 R.MHIEKDETPLSTPTAR.D sp|Q9UI36|DACH1_HUMAN 1 1824.904 2.34 115154 10611 3 1824.901045 609.3086 Dachshund homolog 1 OS=Homo sapiens OX=9606 GN=DACH1 PE=1 SV=4 5.43 2121.7 - 2.47E+06 - - - -1.6182 - 3.309 0.651 - 579.8 1 2 1 -0.003 16 0 0 0 2.83E+08 1.21E+08 - - - 8.8676 1 221125_WJC_METTL3_EV_vs_WT_F08.10612.10612.2 3.14E-10 15/30 K.STAGDTHLGGEDFDNR[166.11].M "sp|P54652|HSP72_HUMAN,sp|P11142|HSP7C_HUMAN,tr|E9PKE3|E9PKE3_HUMAN,tr|E9PN89|E9PN89_HUMAN" 4 1700.7266 0.16 115155 10612 2 1700.72619 851.3706 Heat shock-related 70 kDa protein 2 OS=Homo sapiens OX=9606 GN=HSPA2 PE=1 SV=1 4.22 2121.8 - 838176 - - - -0.227 - 3.103 0.714 - 446.7 1 2 0 -0.0004 16 0 0 0 9.78E+08 6.06E+09 - - - 7.0985 1 221125_WJC_METTL3_EV_vs_WT_F08.10613.10613.2 1.49E-07 20-Nov R.SQYEQLAEQNR.K "sp|P13645|K1C10_HUMAN,tr|A0A1B0GVI3|A0A1B0GVI3_HUMAN" 2 1364.6321 999 115156 10613 2 1364.629392 683.3233 "Keratin, type I cytoskeletal 10 OS=Homo sapiens OX=9606 GN=KRT10 PE=1 SV=6" 4.53 2121.9 - 1.08E+06 - - - -1.9529 - 2.431 0.623 - 505.3 1 2 0 -0.0027 11 0 0 0 2.24E+07 0.00E+00 - - - 6.0447 0.9969 221125_WJC_METTL3_EV_vs_WT_F08.10618.10618.4 0.327 Nov-90 R.MHIEKDETPLSTPTAR.D sp|Q9UI36|DACH1_HUMAN 1 1824.904 1.96 115159 10618 4 1824.900782 457.2333 Dachshund homolog 1 OS=Homo sapiens OX=9606 GN=DACH1 PE=1 SV=4 5.43 2122.6 - 4.59E+06 - - - -1.7623 - 1.898 0.323 - 107.1 1 2 1 -0.0032 16 0 0 0 2.15E+08 1.10E+08 - - - 2.2622 0.9981 221125_WJC_METTL3_EV_vs_WT_F08.10619.10619.4 0.013 15/90 R.SFGTEDR[166.11]PTDR[166.11]PIPPR[166.11].D "sp|Q8ND56|LS14A_HUMAN,tr|I3L4Q1|I3L4Q1_HUMAN,tr|A0A140TA76|A0A140TA76_HUMAN,tr|K7EMZ9|K7EMZ9_HUMAN" 4 1869.9476 3.96 115160 10619 4 1869.942385 468.4942 Protein LSM14 homolog A OS=Homo sapiens OX=9606 GN=LSM14A PE=1 SV=3 5.84 2122.7 - 1.51E+06 - - - -2.7728 - 1.729 0.317 - 137.2 1 2 0 -0.0052 16 0 0 0 1.12E+08 2.83E+07 - - - 2.1766 1 221125_WJC_METTL3_EV_vs_WT_F08.10620.10620.3 1.27E-06 15/60 K.STAGDTHLGGEDFDNR.M "sp|P54652|HSP72_HUMAN,sp|P11142|HSP7C_HUMAN,tr|E9PKE3|E9PKE3_HUMAN,tr|E9PN89|E9PN89_HUMAN" 4 1690.7183 0.17 115161 10620 3 1690.716531 564.58 Heat shock-related 70 kDa protein 2 OS=Homo sapiens OX=9606 GN=HSPA2 PE=1 SV=1 4.22 2122.8 - 4.33E+06 - - - -1.0498 - 2.871 0.622 - 305.5 1 2 0 -0.0018 16 0 0 0 6.70E+09 4.03E+10 - - - 8.1803 1 221125_WJC_METTL3_EV_vs_WT_F08.10627.10627.3 1.98E-06 14/52 R.KGVAINMVTEEDKR.T sp|P60842|IF4A1_HUMAN 1 1588.8243 0.85 115166 10627 3 1588.823091 530.6154 Eukaryotic initiation factor 4A-I OS=Homo sapiens OX=9606 GN=EIF4A1 PE=1 SV=1 6.18 2123.5 - 3.54E+06 - - - -0.7553 - 2.839 0.475 - 335.4 1 2 0 -0.0012 14 0 0 0 1.41E+08 1.67E+08 - - - 6.6085 1 221125_WJC_METTL3_EV_vs_WT_F08.10632.10632.2 1.61E-11 20/26 T.AGDTHLGGEDFDNR[166.11].L "sp|P48741|HSP77_HUMAN,sp|P54652|HSP72_HUMAN,sp|P0DMV8|HS71A_HUMAN,sp|P34931|HS71L_HUMAN,sp|P11142|HSP7C_HUMAN,sp|P0DMV9|HS71B_HUMAN,sp|P17066|HSP76_HUMAN,tr|E9PKE3|E9PKE3_HUMAN,tr|E9PN89|E9PN89_HUMAN,tr|Q53FA3|Q53FA3_HUMAN,tr|V9GZ37|V9GZ37_HUMAN,tr|A0A0G2JIW1|A0A0G2JIW1_HUMAN" 12 1512.6469 0.14 115169 10632 2 1512.641146 757.3307 Putative heat shock 70 kDa protein 7 OS=Homo sapiens OX=9606 GN=HSPA7 PE=5 SV=2 4.22 2124.1 - 1.43E+06 - - - -3.7834 - 3.407 0.683 - 1277.7 1 1 0 -0.0057 14 0 0 0 5.39E+07 3.78E+08 - - - 7.16 1 221125_WJC_METTL3_EV_vs_WT_F08.10634.10634.3 3.66E-10 19/68 K.SIHANFSSGVGTTAASSK.N "sp|Q8IWZ3|ANKH1_HUMAN,tr|A0A0A0MQZ8|A0A0A0MQZ8_HUMAN,tr|H0Y472|H0Y472_HUMAN,tr|H0Y7Y3|H0Y7Y3_HUMAN,tr|H0Y4P6|H0Y4P6_HUMAN,tr|H0Y785|H0Y785_HUMAN" 6 1720.838 1.68 115171 10634 3 1720.836058 574.62 Ankyrin repeat and KH domain-containing protein 1 OS=Homo sapiens OX=9606 GN=ANKHD1 PE=1 SV=1 8.49 2124.3 - 2.64E+06 - - - -1.1442 - 3.472 0.524 - 341.5 1 2 0 -0.002 18 0 0 0 5.63E+08 3.36E+08 - - - 7.481 1 221125_WJC_METTL3_EV_vs_WT_F08.10635.10635.2 7.58E-12 18/30 K.STAGDTHLGGEDFDNR.M "sp|P54652|HSP72_HUMAN,sp|P11142|HSP7C_HUMAN,tr|E9PKE3|E9PKE3_HUMAN,tr|E9PN89|E9PN89_HUMAN" 4 1690.7183 0.16 115172 10635 2 1690.708358 846.3664 Heat shock-related 70 kDa protein 2 OS=Homo sapiens OX=9606 GN=HSPA2 PE=1 SV=1 4.22 2124.4 - 1.65E+06 - - - -5.8839 - 3.558 0.749 - 764.2 1 2 0 -0.0099 16 0 0 0 9.78E+08 6.06E+09 - - - 7.6904 0.9998 221125_WJC_METTL3_EV_vs_WT_F08.10638.10638.3 3.93E-05 Nov-60 R.DGQVINETSQHHDDLE.- sp|P08670|VIME_HUMAN 1 1835.7922 - 115174 10638 3 1835.787833 612.938 Vimentin OS=Homo sapiens OX=9606 GN=VIM PE=1 SV=4 4.28 2124.8 - 5.57E+06 - - - -2.3783 - 2.214 0.441 - 93.4 1 2 0 -0.0044 16 0 0 0 - - - - - 5.4949 0.9999 221125_WJC_METTL3_EV_vs_WT_F08.10641.10641.4 1.40E-06 22/78 R.KGVAINMVTEEDKR.T sp|P60842|IF4A1_HUMAN 1 1588.8243 0.89 115175 10641 4 1588.821297 398.2133 Eukaryotic initiation factor 4A-I OS=Homo sapiens OX=9606 GN=EIF4A1 PE=1 SV=1 6.18 2125.1 - 1.35E+06 - - - -1.8844 - 3.266 0.48 - 610 1 2 0 -0.003 14 0 0 0 3.95E+07 4.43E+07 - - - 3.8338 0.9984 221125_WJC_METTL3_EV_vs_WT_F08.10650.10650.3 7.32E-09 14/68 K.SIHANFSSGVGTTAASSK[136.11].N "sp|Q8IWZ3|ANKH1_HUMAN,tr|A0A0A0MQZ8|A0A0A0MQZ8_HUMAN,tr|H0Y472|H0Y472_HUMAN,tr|H0Y7Y3|H0Y7Y3_HUMAN,tr|H0Y4P6|H0Y4P6_HUMAN,tr|H0Y785|H0Y785_HUMAN" 6 1728.8522 1.68 115178 10650 3 1729.851365 577.2914 Ankyrin repeat and KH domain-containing protein 1 OS=Homo sapiens OX=9606 GN=ANKHD1 PE=1 SV=1 8.49 2126.4 - 9.97E+06 - - - 577.9198 - 3.003 0.527 - 232.8 1 2 0 0.9991 18 0 0 0 5.62E+08 3.36E+08 - - - 6.8769 1 221125_WJC_METTL3_EV_vs_WT_F08.10657.10657.2 5.19E-14 22/34 K.SIHANFSSGVGTTAASSK.N "sp|Q8IWZ3|ANKH1_HUMAN,tr|A0A0A0MQZ8|A0A0A0MQZ8_HUMAN,tr|H0Y472|H0Y472_HUMAN,tr|H0Y7Y3|H0Y7Y3_HUMAN,tr|H0Y4P6|H0Y4P6_HUMAN,tr|H0Y785|H0Y785_HUMAN" 6 1720.838 2.26 115181 10657 2 1720.835902 861.4263 Ankyrin repeat and KH domain-containing protein 1 OS=Homo sapiens OX=9606 GN=ANKHD1 PE=1 SV=1 8.49 2127.2 - 1.91E+06 - - - -1.2349 - 3.975 0.614 - 1295.2 1 2 0 -0.0021 18 0 0 0 4.56E+07 2.02E+07 - - - 6.9682 1 221125_WJC_METTL3_EV_vs_WT_F08.10664.10664.2 5.75E-10 18/24 A.GDTHLGGEDFDNR[166.11].L "sp|P48741|HSP77_HUMAN,sp|P54652|HSP72_HUMAN,sp|P0DMV8|HS71A_HUMAN,sp|P34931|HS71L_HUMAN,sp|P11142|HSP7C_HUMAN,sp|P0DMV9|HS71B_HUMAN,sp|P17066|HSP76_HUMAN,tr|E9PKE3|E9PKE3_HUMAN,tr|E9PN89|E9PN89_HUMAN,tr|Q53FA3|Q53FA3_HUMAN,tr|V9GZ37|V9GZ37_HUMAN,tr|A0A0G2JIW1|A0A0G2JIW1_HUMAN" 12 1441.6098 0.1 115185 10664 2 1441.607291 721.8122 Putative heat shock 70 kDa protein 7 OS=Homo sapiens OX=9606 GN=HSPA7 PE=5 SV=2 4.22 2128 - 4.41E+06 - - - -1.7092 - 2.931 0.742 - 1072.8 1 1 0 -0.0025 13 0 0 0 1.38E+07 1.39E+08 - - - 7.2805 1 221125_WJC_METTL3_EV_vs_WT_F08.10685.10685.2 1.83E-09 22/30 K.ATAGDTHLGGEDFDNR[166.11].L "sp|P48741|HSP77_HUMAN,sp|P0DMV8|HS71A_HUMAN,sp|P34931|HS71L_HUMAN,sp|P0DMV9|HS71B_HUMAN,sp|P17066|HSP76_HUMAN,tr|Q53FA3|Q53FA3_HUMAN,tr|V9GZ37|V9GZ37_HUMAN,tr|A0A0G2JIW1|A0A0G2JIW1_HUMAN" 8 1684.7317 0.14 115191 10685 2 1684.731167 843.3731 Putative heat shock 70 kDa protein 7 OS=Homo sapiens OX=9606 GN=HSPA7 PE=5 SV=2 4.22 2130.9 - 4.08E+06 - - - -0.2932 - 3.728 0.742 - 1217.1 1 2 0 -0.0005 16 0 0 0 6.66E+08 4.69E+09 - - - 7.7564 0.9929 221125_WJC_METTL3_EV_vs_WT_F08.10686.10686.3 7.98E-09 17/56 A.TAGDTHLGGEDFDNR[166.11].L "sp|P48741|HSP77_HUMAN,sp|P54652|HSP72_HUMAN,sp|P0DMV8|HS71A_HUMAN,sp|P34931|HS71L_HUMAN,sp|P11142|HSP7C_HUMAN,sp|P0DMV9|HS71B_HUMAN,sp|P17066|HSP76_HUMAN,tr|E9PKE3|E9PKE3_HUMAN,tr|E9PN89|E9PN89_HUMAN,tr|Q53FA3|Q53FA3_HUMAN,tr|V9GZ37|V9GZ37_HUMAN,tr|A0A0G2JIW1|A0A0G2JIW1_HUMAN" 12 1613.6945 0.09 115192 10686 3 1613.688889 538.9055 Putative heat shock 70 kDa protein 7 OS=Homo sapiens OX=9606 GN=HSPA7 PE=5 SV=2 4.22 2131 - 2.73E+06 - - - -3.5062 - 2.844 0.59 - 319.9 1 1 0 -0.0057 15 0 0 0 1.85E+07 1.95E+08 - - - 7.8437 1 221125_WJC_METTL3_EV_vs_WT_F08.10687.10687.3 0.000287 20/60 K.ATAGDTHLGGEDFDNR.L "sp|P48741|HSP77_HUMAN,sp|P0DMV8|HS71A_HUMAN,sp|P34931|HS71L_HUMAN,sp|P0DMV9|HS71B_HUMAN,sp|P17066|HSP76_HUMAN,tr|Q53FA3|Q53FA3_HUMAN,tr|V9GZ37|V9GZ37_HUMAN,tr|A0A0G2JIW1|A0A0G2JIW1_HUMAN" 8 1674.7234 0.15 115193 10687 3 1674.720788 559.2484 Putative heat shock 70 kDa protein 7 OS=Homo sapiens OX=9606 GN=HSPA7 PE=5 SV=2 4.22 2131.1 - 4.76E+06 - - - -1.5543 - 3.685 0.637 - 581.5 1 2 0 -0.0026 16 0 0 0 7.01E+09 4.77E+10 - - - 8.9878 0.9998 221125_WJC_METTL3_EV_vs_WT_F08.10700.10700.3 0.000116 Nov-44 R.SRTEAESWYQTK.Y "sp|P13647|K2C5_HUMAN,tr|H0YI76|H0YI76_HUMAN,tr|H0YIN9|H0YIN9_HUMAN" 3 1484.6896 172.21 115199 10700 3 1484.686874 495.9038 "Keratin, type II cytoskeletal 5 OS=Homo sapiens OX=9606 GN=KRT5 PE=1 SV=3" 5.86 2132.7 - 3.48E+06 - - - -1.8172 - 2.411 0.493 - 188.5 1 2 1 -0.0027 12 0 0 0 1.03E+09 5.99E+06 - - - 6.4751 1 221125_WJC_METTL3_EV_vs_WT_F08.10710.10710.2 1.64E-14 22/30 K.ATAGDTHLGGEDFDNR.L "sp|P48741|HSP77_HUMAN,sp|P0DMV8|HS71A_HUMAN,sp|P34931|HS71L_HUMAN,sp|P0DMV9|HS71B_HUMAN,sp|P17066|HSP76_HUMAN,tr|Q53FA3|Q53FA3_HUMAN,tr|V9GZ37|V9GZ37_HUMAN,tr|A0A0G2JIW1|A0A0G2JIW1_HUMAN" 8 1674.7234 0.14 115206 10710 2 1674.720962 838.369 Putative heat shock 70 kDa protein 7 OS=Homo sapiens OX=9606 GN=HSPA7 PE=5 SV=2 4.22 2134 - 2.62E+06 - - - -1.4504 - 3.799 0.75 - 1298.8 1 2 0 -0.0024 16 0 0 0 6.66E+08 4.69E+09 - - - 7.8613 1 221125_WJC_METTL3_EV_vs_WT_F08.10716.10716.2 7.34E-10 20/28 A.TAGDTHLGGEDFDNR[166.11].L "sp|P48741|HSP77_HUMAN,sp|P54652|HSP72_HUMAN,sp|P0DMV8|HS71A_HUMAN,sp|P34931|HS71L_HUMAN,sp|P11142|HSP7C_HUMAN,sp|P0DMV9|HS71B_HUMAN,sp|P17066|HSP76_HUMAN,tr|E9PKE3|E9PKE3_HUMAN,tr|E9PN89|E9PN89_HUMAN,tr|Q53FA3|Q53FA3_HUMAN,tr|V9GZ37|V9GZ37_HUMAN,tr|A0A0G2JIW1|A0A0G2JIW1_HUMAN" 12 1613.6945 0.04 115209 10716 2 1613.694315 807.8545 Putative heat shock 70 kDa protein 7 OS=Homo sapiens OX=9606 GN=HSPA7 PE=5 SV=2 4.22 2134.7 - 1.38E+06 - - - -0.1438 - 3.372 0.659 - 1132.8 1 1 0 -0.0002 15 0 0 0 4.97E+06 1.33E+08 - - - 6.8967 1 221125_WJC_METTL3_EV_vs_WT_F08.10725.10725.2 1.43E-11 18/26 T.AGDTHLGGEDFDNR.L "sp|P48741|HSP77_HUMAN,sp|P54652|HSP72_HUMAN,sp|P0DMV8|HS71A_HUMAN,sp|P34931|HS71L_HUMAN,sp|P11142|HSP7C_HUMAN,sp|P0DMV9|HS71B_HUMAN,sp|P17066|HSP76_HUMAN,tr|E9PKE3|E9PKE3_HUMAN,tr|E9PN89|E9PN89_HUMAN,tr|Q53FA3|Q53FA3_HUMAN,tr|V9GZ37|V9GZ37_HUMAN,tr|A0A0G2JIW1|A0A0G2JIW1_HUMAN" 12 1502.6386 0.15 115216 10725 2 1502.63794 752.3266 Putative heat shock 70 kDa protein 7 OS=Homo sapiens OX=9606 GN=HSPA7 PE=5 SV=2 4.22 2135.6 - 1.25E+06 - - - -0.4386 - 3.187 0.703 - 995.5 1 1 0 -0.0007 14 0 0 0 9.54E+07 6.31E+08 - - - 7.1418 1 221125_WJC_METTL3_EV_vs_WT_F08.10729.10729.3 4.16E-07 Dec-60 K.STAGDTHLGGEDFDNR[166.11].M "sp|P54652|HSP72_HUMAN,sp|P11142|HSP7C_HUMAN,tr|E9PKE3|E9PKE3_HUMAN,tr|E9PN89|E9PN89_HUMAN" 4 1700.7266 0.17 115218 10729 3 1700.722493 567.9161 Heat shock-related 70 kDa protein 2 OS=Homo sapiens OX=9606 GN=HSPA2 PE=1 SV=1 4.22 2136.1 - 1.34E+08 - - - -2.4007 - 2.577 0.602 - 180.7 1 2 0 -0.0041 16 0 0 0 6.71E+09 4.05E+10 - - - 7.6795 1 221125_WJC_METTL3_EV_vs_WT_F08.10730.10730.2 3.17E-07 17/22 R.SRTEAESWYQTK.Y "sp|P13647|K2C5_HUMAN,tr|H0YI76|H0YI76_HUMAN,tr|H0YIN9|H0YIN9_HUMAN" 3 1484.6896 999 115219 10730 2 1484.687895 743.3521 "Keratin, type II cytoskeletal 5 OS=Homo sapiens OX=9606 GN=KRT5 PE=1 SV=3" 5.86 2136.2 - 4.98E+06 - - - -1.1295 - 2.701 0.589 - 764 1 2 1 -0.0017 12 0 0 0 2.62E+08 0.00E+00 - - - 6.0052 0.8858 221125_WJC_METTL3_EV_vs_WT_F08.10737.10737.4 0.487 May-84 Q.GSDPSGWEDC[160.03]SFDNR.L "sp|B2RTY4|MYO9A_HUMAN,tr|H3BMM1|H3BMM1_HUMAN,tr|H3BRD5|H3BRD5_HUMAN" 3 1727.6482 0.18 115221 10737 4 1727.635472 432.9193 Unconventional myosin-IXa OS=Homo sapiens OX=9606 GN=MYO9A PE=1 SV=2 3.84 2137.2 - 1.16E+07 - - - -7.3545 - 1.203 0.614 - 24.8 1 1 0 -0.0127 15 0 0 0 4.06E+08 2.30E+09 - - - 4.6329 1 221125_WJC_METTL3_EV_vs_WT_F08.10748.10748.3 7.34E-07 14/40 M.SDTWSSIQAHK[136.11].K "sp|Q86U44|MTA70_HUMAN,tr|B4E349|B4E349_HUMAN,tr|F5H6D8|F5H6D8_HUMAN,tr|B4DTN4|B4DTN4_HUMAN" 4 1266.6084 0.01 115224 10748 3 1266.606197 423.2101 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 6.46 2138.8 - 2.25E+06 - - - -1.7511 - 2.515 0.507 - 362 1 2 0 -0.0022 11 0 0 0 2.38E+06 1.87E+08 - - - 6.812 1 221125_WJC_METTL3_EV_vs_WT_F08.10756.10756.3 7.01E-09 17/48 K.SYC[160.03]AEIAHNVSSK[136.11].N "sp|P62910|RL32_HUMAN,tr|F8W727|F8W727_HUMAN,tr|D3YTB1|D3YTB1_HUMAN" 3 1472.6809 1.68 115228 10756 3 1472.677686 491.9009 60S ribosomal protein L32 OS=Homo sapiens OX=9606 GN=RPL32 PE=1 SV=2 6.46 2139.8 - 1.89E+06 - - - -2.2014 - 2.485 0.661 - 242.6 1 2 0 -0.0032 13 0 0 0 4.33E+07 2.57E+07 - - - 8.3766 0.9986 221125_WJC_METTL3_EV_vs_WT_F08.10761.10761.3 2.55E-08 13/56 A.TAGDTHLGGEDFDNR.L "sp|P48741|HSP77_HUMAN,sp|P54652|HSP72_HUMAN,sp|P0DMV8|HS71A_HUMAN,sp|P34931|HS71L_HUMAN,sp|P11142|HSP7C_HUMAN,sp|P0DMV9|HS71B_HUMAN,sp|P17066|HSP76_HUMAN,tr|E9PKE3|E9PKE3_HUMAN,tr|E9PN89|E9PN89_HUMAN,tr|Q53FA3|Q53FA3_HUMAN,tr|V9GZ37|V9GZ37_HUMAN,tr|A0A0G2JIW1|A0A0G2JIW1_HUMAN" 12 1603.6863 0.1 115230 10761 3 1603.684809 535.5694 Putative heat shock 70 kDa protein 7 OS=Homo sapiens OX=9606 GN=HSPA7 PE=5 SV=2 4.22 2140.5 - 1.01E+06 - - - -0.9154 - 2.644 0.594 - 194.8 1 1 0 -0.0015 15 0 0 0 1.59E+07 1.55E+08 - - - 7.6992 1 221125_WJC_METTL3_EV_vs_WT_F08.10773.10773.3 1.22E-08 17/48 K.SYC[160.03]AEIAHNVSSK.N "sp|P62910|RL32_HUMAN,tr|F8W727|F8W727_HUMAN,tr|D3YTB1|D3YTB1_HUMAN" 3 1464.6667 1.7 115237 10773 3 1464.663614 489.2295 60S ribosomal protein L32 OS=Homo sapiens OX=9606 GN=RPL32 PE=1 SV=2 6.46 2141.9 - 803394 - - - -2.1261 - 2.742 0.613 - 284.3 1 2 0 -0.0031 13 0 0 0 4.38E+07 2.57E+07 - - - 8.1083 0.9998 221125_WJC_METTL3_EV_vs_WT_F08.10776.10776.2 4.73E-06 20-Oct M.SDTWSSIQAHK[136.11].K "sp|Q86U44|MTA70_HUMAN,tr|B4E349|B4E349_HUMAN,tr|F5H6D8|F5H6D8_HUMAN,tr|B4DTN4|B4DTN4_HUMAN" 4 1266.6084 0.8 115240 10776 2 1266.606608 634.3115 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 6.46 2142.1 - 1.59E+06 - - - -1.4266 - 2.011 0.519 - 372.7 1 2 0 -0.0018 11 0 0 0 3.17E+07 3.98E+07 - - - 4.7637 0.991 221125_WJC_METTL3_EV_vs_WT_F08.10785.10785.3 0.00014 15/56 R.K[136.11]GDGAPVTTVPVPNR[166.11].L sp|Q8IVW6|ARI3B_HUMAN 1 1524.8379 1.06 115244 10785 3 1524.832764 509.2866 AT-rich interactive domain-containing protein 3B OS=Homo sapiens OX=9606 GN=ARID3B PE=1 SV=2 8.75 2143.3 - 660148 - - - -3.3754 - 2.344 0.191 - 265.5 1 2 0 -0.0051 15 0 0 0 1.84E+07 1.74E+07 - - - 2.8909 0.9999 221125_WJC_METTL3_EV_vs_WT_F08.10789.10789.3 0.000315 Dec-56 K.LSGWGNVSKPSGTTK.S "sp|Q6Y7W6|GGYF2_HUMAN,tr|A0A7I2V3H7|A0A7I2V3H7_HUMAN,tr|I1E4Y6|I1E4Y6_HUMAN,tr|A0A7I2V516|A0A7I2V516_HUMAN,tr|A0A7I2V3H0|A0A7I2V3H0_HUMAN,tr|A0A7I2V361|A0A7I2V361_HUMAN" 6 1517.7838 2.83 115246 10789 3 1517.782326 506.9352 GRB10-interacting GYF protein 2 OS=Homo sapiens OX=9606 GN=GIGYF2 PE=1 SV=1 10 2143.8 - 786122 - - - -0.9758 - 2.319 0.426 - 156.4 1 2 0 -0.0015 15 0 0 0 4.03E+07 1.42E+07 - - - 5.4839 0.9999 221125_WJC_METTL3_EV_vs_WT_F08.10790.10790.3 3.14E-07 17/60 K.NLPLADQGSSHHITVK.L sp|P15924|DESP_HUMAN 1 1715.8955 28.26 115247 10790 3 1715.890276 572.9724 Desmoplakin OS=Homo sapiens OX=9606 GN=DSP PE=1 SV=3 6.92 2143.9 - 860166 - - - -3.034 - 3.115 0.504 - 247.6 1 2 0 -0.0052 16 0 0 0 2.03E+08 7.18E+06 - - - 7.0731 1 221125_WJC_METTL3_EV_vs_WT_F08.10791.10791.4 2.97E-08 17/90 K.NLPLADQGSSHHITVK.L sp|P15924|DESP_HUMAN 1 1715.8955 28.91 115248 10791 4 1715.892343 429.9811 Desmoplakin OS=Homo sapiens OX=9606 GN=DSP PE=1 SV=3 6.92 2144 - 1.88E+06 - - - -1.8294 - 3.198 0.502 - 175.1 1 2 0 -0.0031 16 0 0 0 2.56E+08 8.84E+06 - - - 4.004 0.9995 221125_WJC_METTL3_EV_vs_WT_F08.10794.10794.4 3.57E-05 16/78 K.RVSISEGDDKIEYR.A "sp|P22087|FBRL_HUMAN,tr|M0R299|M0R299_HUMAN,tr|M0R0P1|M0R0P1_HUMAN,tr|M0R1H0|M0R1H0_HUMAN,tr|M0QXL5|M0QXL5_HUMAN,tr|M0R2Q4|M0R2Q4_HUMAN,tr|M0R2B0|M0R2B0_HUMAN,tr|M0R2U2|M0R2U2_HUMAN" 8 1665.8322 1.66 115251 10794 4 1665.828452 417.4653 rRNA 2'-O-methyltransferase fibrillarin OS=Homo sapiens OX=9606 GN=FBL PE=1 SV=2 4.78 2144.3 - 574580 - - - -2.2577 - 2.993 0.431 - 286.1 1 2 1 -0.0038 14 0 0 0 5.02E+06 3.02E+06 - - - 3.3754 0.9783 221125_WJC_METTL3_EV_vs_WT_F08.10802.10802.3 2.36E-05 Dec-60 K.IK[136.11]ELNNTC[160.03]EPVVTQPK[136.11].P "sp|Q92598|HS105_HUMAN,tr|Q5TBM3|Q5TBM3_HUMAN,tr|A0A0A0MSM0|A0A0A0MSM0_HUMAN" 3 1884.995 0.14 115257 10802 3 1884.991649 629.3389 Heat shock protein 105 kDa OS=Homo sapiens OX=9606 GN=HSPH1 PE=1 SV=1 6.14 2145.2 - 900155 - - - -1.7772 - 2.376 0.517 - 188 1 1 1 -0.0034 16 0 0 0 2.12E+06 1.47E+07 - - - 6.5237 1 221125_WJC_METTL3_EV_vs_WT_F08.10803.10803.3 6.66E-07 14/64 R.VASETHSEGSEYEELPK.R sp|Q5JSZ5|PRC2B_HUMAN 1 1890.8483 1.53 115258 10803 3 1890.847882 631.29 Protein PRRC2B OS=Homo sapiens OX=9606 GN=PRRC2B PE=1 SV=2 4.32 2145.4 - 702138 - - - -0.2301 - 2.038 0.578 - 177.2 1 2 0 -0.0004 17 0 0 0 3.75E+07 2.45E+07 - - - 6.7827 0.9999 221125_WJC_METTL3_EV_vs_WT_F08.10805.10805.3 9.33E-05 13/56 R.KGDGAPVTTVPVPNR.L sp|Q8IVW6|ARI3B_HUMAN 1 1506.8154 1.01 115260 10805 3 1506.812799 503.2791 AT-rich interactive domain-containing protein 3B OS=Homo sapiens OX=9606 GN=ARID3B PE=1 SV=2 8.75 2145.6 - 620210 - - - -1.7534 - 2.565 0.428 - 167.3 1 2 0 -0.0026 15 0 0 0 1.73E+07 1.72E+07 - - - 5.769 0.9852 221125_WJC_METTL3_EV_vs_WT_F08.10806.10806.4 0.000259 Dec-96 M.AEVDAAMAARPHSIDGR.V "sp|P22626|ROA2_HUMAN,tr|A0A7I2YQN4|A0A7I2YQN4_HUMAN,tr|A0A7I2V4N0|A0A7I2V4N0_HUMAN,tr|A0A024RA28|A0A024RA28_HUMAN,tr|A0A7I2V4N1|A0A7I2V4N1_HUMAN,tr|A0A7I2V4I6|A0A7I2V4I6_HUMAN,tr|A0A087WUI2|A0A087WUI2_HUMAN,tr|A0A7I2V4S4|A0A7I2V4S4_HUMAN,tr|A0A7I2V323|A0A7I2V323_HUMAN,tr|A0A7I2V3P1|A0A7I2V3P1_HUMAN,tr|A0A7I2V3P7|A0A7I2V3P7_HUMAN" 11 1765.853 5.5 115261 10806 4 1765.854346 442.4705 Heterogeneous nuclear ribonucleoproteins A2\B1 OS=Homo sapiens OX=9606 GN=HNRNPA2B1 PE=1 SV=2 5.38 2145.8 - 601083 - - - 0.7815 - 2.404 0.406 - 100 1 1 0 0.0014 17 0 0 0 8.57E+06 1.56E+06 - - - 3.064 1 221125_WJC_METTL3_EV_vs_WT_F08.10808.10808.2 3.01E-05 30-Nov K.STSNETMQAVEDGDSK.S "sp|Q2KHR3|QSER1_HUMAN,tr|A0A3B3IRW6|A0A3B3IRW6_HUMAN" 2 1697.705 4.06 115263 10808 2 1697.707151 849.8598 Glutamine and serine-rich protein 1 OS=Homo sapiens OX=9606 GN=QSER1 PE=1 SV=3 3.92 2146 - 403545 - - - 1.2529 - 2.596 0.616 - 453.7 1 2 0 0.0021 16 0 0 0 5.83E+06 1.44E+06 - - - 5.9355 0.9962 221125_WJC_METTL3_EV_vs_WT_F08.10816.10816.3 0.134 13/36 K.KKESILDLSK.Y "sp|Q9UK45|LSM7_HUMAN,tr|K7ENY5|K7ENY5_HUMAN,tr|K7EML7|K7EML7_HUMAN" 3 1159.6812 2.34 115269 10816 3 1159.680278 387.5677 U6 snRNA-associated Sm-like protein LSm7 OS=Homo sapiens OX=9606 GN=LSM7 PE=1 SV=1 8.5 2146.9 - 1.02E+06 - - - -0.8287 - 1.867 0.276 - 266.5 1 2 1 -0.001 10 0 0 0 1.57E+07 6.72E+06 - - - 3.4402 0.9998 221125_WJC_METTL3_EV_vs_WT_F08.10817.10817.3 0.000116 14/72 R.LK[136.11]EQGQAPITPQQGQALAK[136.11].Q sp|P84095|RHOG_HUMAN 1 2021.124 0.88 115270 10817 3 2021.125671 674.7153 Rho-related GTP-binding protein RhoG OS=Homo sapiens OX=9606 GN=RHOG PE=1 SV=1 8.59 2147 - 989470 - - - 0.8075 - 2.662 0.487 - 180 1 2 1 0.0016 19 0 0 0 3.23E+07 3.66E+07 - - - 6.3745 1 221125_WJC_METTL3_EV_vs_WT_F08.10818.10818.3 0.000117 13/56 K.LSGWGNVSK[136.11]PSGTTK[136.11].S "sp|Q6Y7W6|GGYF2_HUMAN,tr|A0A7I2V3H7|A0A7I2V3H7_HUMAN,tr|I1E4Y6|I1E4Y6_HUMAN,tr|A0A7I2V516|A0A7I2V516_HUMAN,tr|A0A7I2V3H0|A0A7I2V3H0_HUMAN,tr|A0A7I2V361|A0A7I2V361_HUMAN" 6 1533.8122 2.99 115271 10818 3 1533.811327 512.278 GRB10-interacting GYF protein 2 OS=Homo sapiens OX=9606 GN=GIGYF2 PE=1 SV=1 10 2147.1 - 774995 - - - -0.5737 - 2.523 0.445 - 215.2 1 2 0 -0.0009 15 0 0 0 4.03E+07 1.35E+07 - - - 5.9159 0.9999 221125_WJC_METTL3_EV_vs_WT_F08.10819.10819.3 8.92E-06 19/52 R.RYNIPHGPVVGSTR.R "sp|P50402|EMD_HUMAN,tr|A0A804HLA2|A0A804HLA2_HUMAN,tr|A0A804HIV7|A0A804HIV7_HUMAN" 3 1551.827 1.52 115272 10819 3 1551.823632 518.2829 Emerin OS=Homo sapiens OX=9606 GN=EMD PE=1 SV=1 10.84 2147.2 - 414130 - - - -2.1761 - 3.481 0.435 - 673.7 1 2 0 -0.0034 14 0 0 0 1.29E+07 8.48E+06 - - - 6.7037 1 221125_WJC_METTL3_EV_vs_WT_F08.10824.10824.4 1.69E-08 23/102 K.TLQAGLSSNHVSHGEVLR[166.11].K "sp|O95163|ELP1_HUMAN,tr|A0A6Q8PFB7|A0A6Q8PFB7_HUMAN,tr|A0A6Q8PFH9|A0A6Q8PFH9_HUMAN,tr|A0A6Q8PH48|A0A6Q8PH48_HUMAN,tr|A0A6Q8PHC9|A0A6Q8PHC9_HUMAN,tr|A0A6Q8PHA0|A0A6Q8PHA0_HUMAN,tr|A0A6Q8PHI5|A0A6Q8PHI5_HUMAN,tr|A0A6Q8PF69|A0A6Q8PF69_HUMAN,tr|A0A6Q8PF66|A0A6Q8PF66_HUMAN,tr|A0A6Q8PGW3|A0A6Q8PGW3_HUMAN,tr|A0A6Q8PG86|A0A6Q8PG86_HUMAN,tr|A0A6Q8PGR0|A0A6Q8PGR0_HUMAN,tr|A0A6Q8PEX6|A0A6Q8PEX6_HUMAN,tr|F5H2T0|F5H2T0_HUMAN,tr|A0A6Q8PHF4|A0A6Q8PHF4_HUMAN,tr|A0A6Q8PFN8|A0A6Q8PFN8_HUMAN" 16 1913.9947 0.58 115275 10824 4 1913.994234 479.5059 Elongator complex protein 1 OS=Homo sapiens OX=9606 GN=ELP1 PE=1 SV=3 6.61 2147.8 - 767196 - - - -0.2398 - 4.08 0.543 - 313.1 1 2 0 -0.0005 18 0 0 0 3.14E+06 5.46E+06 - - - 4.4338 0.9999 221125_WJC_METTL3_EV_vs_WT_F08.10826.10826.3 1.62E-06 21/72 R.LKEQGQAPITPQQGQALAK.Q sp|P84095|RHOG_HUMAN 1 2005.0956 0.89 115277 10826 3 2005.095163 669.3725 Rho-related GTP-binding protein RhoG OS=Homo sapiens OX=9606 GN=RHOG PE=1 SV=1 8.59 2148 - 961849 - - - -0.2374 - 3.136 0.526 - 510.9 1 2 1 -0.0005 19 0 0 0 3.24E+07 3.66E+07 - - - 7.2122 0.978 221125_WJC_METTL3_EV_vs_WT_F08.10827.10827.3 0.000768 Nov-36 K.K[136.11]K[136.11]ESILDLSK[136.11].Y "sp|Q9UK45|LSM7_HUMAN,tr|K7ENY5|K7ENY5_HUMAN,tr|K7EML7|K7EML7_HUMAN" 3 1183.7238 2.34 115278 10827 3 1183.724424 395.5819 U6 snRNA-associated Sm-like protein LSm7 OS=Homo sapiens OX=9606 GN=LSM7 PE=1 SV=1 8.5 2148.2 - 869196 - - - 0.4942 - 1.971 0.155 - 181 1 2 1 0.0006 10 0 0 0 1.57E+07 6.72E+06 - - - 2.2496 0.9954 221125_WJC_METTL3_EV_vs_WT_F08.10828.10828.4 0.0577 12/102 K.TLQAGLSSNHVSHGEVLR.K "sp|O95163|ELP1_HUMAN,tr|A0A6Q8PFB7|A0A6Q8PFB7_HUMAN,tr|A0A6Q8PFH9|A0A6Q8PFH9_HUMAN,tr|A0A6Q8PH48|A0A6Q8PH48_HUMAN,tr|A0A6Q8PHC9|A0A6Q8PHC9_HUMAN,tr|A0A6Q8PHA0|A0A6Q8PHA0_HUMAN,tr|A0A6Q8PHI5|A0A6Q8PHI5_HUMAN,tr|A0A6Q8PF69|A0A6Q8PF69_HUMAN,tr|A0A6Q8PF66|A0A6Q8PF66_HUMAN,tr|A0A6Q8PGW3|A0A6Q8PGW3_HUMAN,tr|A0A6Q8PG86|A0A6Q8PG86_HUMAN,tr|A0A6Q8PGR0|A0A6Q8PGR0_HUMAN,tr|A0A6Q8PEX6|A0A6Q8PEX6_HUMAN,tr|F5H2T0|F5H2T0_HUMAN,tr|A0A6Q8PHF4|A0A6Q8PHF4_HUMAN,tr|A0A6Q8PFN8|A0A6Q8PFN8_HUMAN" 16 1903.9864 0.58 115279 10828 4 1903.983097 477.0039 Elongator complex protein 1 OS=Homo sapiens OX=9606 GN=ELP1 PE=1 SV=3 6.61 2148.2 - 806434 - - - -1.7469 - 1.875 0.24 - 64.1 1 2 0 -0.0033 18 0 0 0 3.14E+06 5.46E+06 - - - 1.5294 0.9999 221125_WJC_METTL3_EV_vs_WT_F08.10832.10832.3 1.42E-06 13/48 K.SGNALFHASTLHR[166.11].L sp|Q14152|EIF3A_HUMAN 1 1419.7247 1.12 115283 10832 3 1419.72594 474.2488 Eukaryotic translation initiation factor 3 subunit A OS=Homo sapiens OX=9606 GN=EIF3A PE=1 SV=1 9.51 2148.7 - 524249 - - - 0.8974 - 2.832 0.37 - 235.9 1 2 0 0.0013 13 0 0 0 6.83E+06 6.08E+06 - - - 5.4872 1 221125_WJC_METTL3_EV_vs_WT_F08.10837.10837.3 6.88E-07 17/60 R.ASGNYATVISHNPETK[136.11].K "sp|P62917|RL8_HUMAN,tr|G3V1A1|G3V1A1_HUMAN,tr|E9PKZ0|E9PKZ0_HUMAN" 3 1695.8308 1.01 115286 10837 3 1695.830421 566.2842 60S ribosomal protein L8 OS=Homo sapiens OX=9606 GN=RPL8 PE=1 SV=2 6.79 2149.4 - 4.84E+06 - - - -0.2017 - 3.379 0.581 - 527 1 2 0 -0.0003 16 0 0 0 1.57E+08 1.56E+08 - - - 8.1416 0.9995 221125_WJC_METTL3_EV_vs_WT_F08.10838.10838.4 0.00179 13/84 R.ETNPHHPPAWIASAR.L sp|O94906|PRP6_HUMAN 1 1682.8277 2.25 115287 10838 4 1682.829231 421.7142 Pre-mRNA-processing factor 6 OS=Homo sapiens OX=9606 GN=PRPF6 PE=1 SV=1 7.02 2149.5 - 1.77E+06 - - - 0.8878 - 2.216 0.327 - 114 1 2 0 0.0015 15 0 0 0 5.89E+07 2.62E+07 - - - 2.3565 1 221125_WJC_METTL3_EV_vs_WT_F08.10840.10840.3 1.31E-11 14/64 R.VASETHSEGSEYEELPK[136.11].R sp|Q5JSZ5|PRC2B_HUMAN 1 1898.8625 1.53 115289 10840 3 1898.859222 633.9614 Protein PRRC2B OS=Homo sapiens OX=9606 GN=PRRC2B PE=1 SV=2 4.32 2149.6 - 2.61E+06 - - - -1.7352 - 3.009 0.698 - 159.5 1 2 0 -0.0033 17 0 0 0 3.75E+07 2.45E+07 - - - 9.1041 1 221125_WJC_METTL3_EV_vs_WT_F08.10841.10841.3 8.74E-14 29/52 L.PLADQGSSHHITVK.L sp|P15924|DESP_HUMAN 1 1488.7685 11.17 115290 10841 3 1488.771174 497.2634 Desmoplakin OS=Homo sapiens OX=9606 GN=DSP PE=1 SV=3 7.33 2149.7 - 1.25E+06 - - - 1.8022 - 4.729 0.69 - 1126.9 1 1 0 0.0027 14 0 0 0 3.94E+07 3.53E+06 - - - 10.3611 1 221125_WJC_METTL3_EV_vs_WT_F08.10842.10842.4 7.99E-07 13/78 R.LLEGEDAHLTQYKK.E "sp|Q04695|K1C17_HUMAN,tr|A0A3B3IS58|A0A3B3IS58_HUMAN,tr|F5GWP8|F5GWP8_HUMAN" 3 1643.8519 10.28 115291 10842 4 1643.853201 411.9702 "Keratin, type I cytoskeletal 17 OS=Homo sapiens OX=9606 GN=KRT17 PE=1 SV=2" 5.45 2149.8 - 1.20E+06 - - - 0.8 - 2.465 0.478 - 113.8 1 2 0 0.0013 14 0 0 0 4.31E+07 4.19E+06 - - - 3.7145 0.9976 221125_WJC_METTL3_EV_vs_WT_F08.10843.10843.4 0.0412 Dec-96 R.ATSLGRPEEEEDELAHR.C "sp|P36551|HEM6_HUMAN,tr|D6RER6|D6RER6_HUMAN" 2 1937.9079 1.43 115292 10843 4 1937.91188 485.4843 "Oxygen-dependent coproporphyrinogen-III oxidase, mitochondrial OS=Homo sapiens OX=9606 GN=CPOX PE=1 SV=3" 4.41 2149.9 - 897727 - - - 2.0548 - 2.312 0.273 - 130.4 1 2 0 0.004 17 0 0 0 7.04E+07 4.91E+07 - - - 1.8921 0.9967 221125_WJC_METTL3_EV_vs_WT_F08.10848.10848.3 0.000231 Nov-60 K.VDSPLPSDKAPTPPGK.G sp|Q12893|TM115_HUMAN 1 1604.841 2.86 115297 10848 3 1604.843495 535.9543 Transmembrane protein 115 OS=Homo sapiens OX=9606 GN=TMEM115 PE=1 SV=1 5.93 2150.4 - 525923 - - - 1.5628 - 2.038 0.312 - 132.1 1 2 1 0.0025 16 0 0 0 6.33E+06 2.21E+06 - - - 3.8446 0.9999 221125_WJC_METTL3_EV_vs_WT_F08.10850.10850.4 4.19E-05 17/90 K.NLPLADQGSSHHITVK[136.11].L sp|P15924|DESP_HUMAN 1 1723.9097 28.79 115299 10850 4 1723.909913 431.9847 Desmoplakin OS=Homo sapiens OX=9606 GN=DSP PE=1 SV=3 6.92 2150.7 - 451280 - - - 0.134 - 2.446 0.434 - 185 1 2 0 0.0002 16 0 0 0 2.54E+08 8.84E+06 - - - 3.3186 0.9983 221125_WJC_METTL3_EV_vs_WT_F08.10851.10851.3 0.0214 Oct-60 K.NLPLADQGSSHHITVK[136.11].L sp|P15924|DESP_HUMAN 1 1723.9097 28.18 115300 10851 3 1723.910753 575.6438 Desmoplakin OS=Homo sapiens OX=9606 GN=DSP PE=1 SV=3 6.92 2150.8 - 380676 - - - 0.6213 - 1.968 0.252 - 80 2 2 0 0.0011 16 0 0 0 2.02E+08 7.18E+06 - - - 2.9471 0.9998 221125_WJC_METTL3_EV_vs_WT_F08.10852.10852.3 1.34E-05 13/60 K.VDSPLPSDK[136.11]APTPPGK[136.11].G sp|Q12893|TM115_HUMAN 1 1620.8694 1.45 115301 10852 3 1620.86881 541.2971 Transmembrane protein 115 OS=Homo sapiens OX=9606 GN=TMEM115 PE=1 SV=1 5.93 2150.9 - 310845 - - - -0.356 - 2.632 0.432 - 237 1 2 1 -0.0006 16 0 0 0 7.73E+07 5.35E+07 - - - 5.8393 1 221125_WJC_METTL3_EV_vs_WT_F08.10857.10857.3 3.83E-08 14/60 K.ATAGDTHLGGEDFDNR[166.11].L "sp|P48741|HSP77_HUMAN,sp|P0DMV8|HS71A_HUMAN,sp|P34931|HS71L_HUMAN,sp|P0DMV9|HS71B_HUMAN,sp|P17066|HSP76_HUMAN,tr|Q53FA3|Q53FA3_HUMAN,tr|V9GZ37|V9GZ37_HUMAN,tr|A0A0G2JIW1|A0A0G2JIW1_HUMAN" 8 1684.7317 0.16 115305 10857 3 1684.73324 562.5845 Putative heat shock 70 kDa protein 7 OS=Homo sapiens OX=9606 GN=HSPA7 PE=5 SV=2 4.22 2151.5 - 9.59E+06 - - - 0.9372 - 2.895 0.633 - 284.8 1 2 0 0.0016 16 0 0 0 2.25E+07 1.41E+08 - - - 8.3244 0.9997 221125_WJC_METTL3_EV_vs_WT_F08.10858.10858.2 0.00975 12-Sep R.LASYLDK.V "sp|Q04695|K1C17_HUMAN,sp|Q99456|K1C12_HUMAN,sp|P13645|K1C10_HUMAN,sp|P02533|K1C14_HUMAN,sp|P08727|K1C19_HUMAN,sp|P35527|K1C9_HUMAN,sp|P08779|K1C16_HUMAN,sp|P19012|K1C15_HUMAN,tr|K7EPJ9|K7EPJ9_HUMAN,tr|C9JM50|C9JM50_HUMAN,tr|A0A1B0GVI3|A0A1B0GVI3_HUMAN,tr|A0A3B3ITG2|A0A3B3ITG2_HUMAN" 12 808.4331 25.67 115306 10858 2 808.432799 405.2238 "Keratin, type I cytoskeletal 17 OS=Homo sapiens OX=9606 GN=KRT17 PE=1 SV=2" 5.83 2151.7 - 1.37E+06 - - - -0.3352 - 1.83 0.365 - 235.5 1 2 0 -0.0003 7 0 0 0 1.43E+07 5.58E+05 - - - 3.6516 0.9138 221125_WJC_METTL3_EV_vs_WT_F08.10859.10859.3 1.88 Sep-48 K.KINSWVESQTNEK.L "sp|P48594|SPB4_HUMAN,sp|P29508|SPB3_HUMAN,tr|C9JZ65|C9JZ65_HUMAN,tr|H0Y5H9|H0Y5H9_HUMAN" 4 1561.7736 1.17 115307 10859 3 1561.775874 521.5985 Serpin B4 OS=Homo sapiens OX=9606 GN=SERPINB4 PE=1 SV=2 6.14 2151.8 - 851765 - - - 1.433 - 1.306 0.13 - 84.4 1 2 0 0.0022 13 0 0 0 2.65E+07 2.25E+07 - - - 0.7126 0.9997 221125_WJC_METTL3_EV_vs_WT_F08.10860.10860.3 8.75E-05 19/52 R.DTALTIAADKGHYK.F "sp|O75179|ANR17_HUMAN,sp|Q8IWZ3|ANKH1_HUMAN,tr|E9PDP5|E9PDP5_HUMAN,tr|H0YM23|H0YM23_HUMAN,tr|H3BLS9|H3BLS9_HUMAN,tr|H0YLQ3|H0YLQ3_HUMAN,tr|H7C2F5|H7C2F5_HUMAN" 7 1502.7729 0.39 115308 10860 3 1502.775018 501.9316 Ankyrin repeat domain-containing protein 17 OS=Homo sapiens OX=9606 GN=ANKRD17 PE=1 SV=3 6.75 2151.9 - 814537 - - - 1.4041 - 3.432 0.381 - 509.8 1 2 1 0.0021 14 0 0 0 7.17E+06 1.86E+07 - - - 6.0643 1 221125_WJC_METTL3_EV_vs_WT_F08.10863.10863.2 5.13E-10 14/30 R.ASGNYATVISHNPETK.K "sp|P62917|RL8_HUMAN,tr|G3V1A1|G3V1A1_HUMAN,tr|E9PKZ0|E9PKZ0_HUMAN" 3 1687.8166 2.34 115311 10863 2 1687.816876 844.9156 60S ribosomal protein L8 OS=Homo sapiens OX=9606 GN=RPL8 PE=1 SV=2 6.79 2152.3 - 314392 - - - 0.1854 - 2.828 0.706 - 612.1 1 2 0 0.0003 16 0 0 0 2.24E+07 9.58E+06 - - - 6.8112 1 221125_WJC_METTL3_EV_vs_WT_F08.10864.10864.2 5.57E-06 14/26 R.SSQSSSQQFSGIGR[166.11].S "sp|Q92841|DDX17_HUMAN,tr|A0A5H1ZRQ2|A0A5H1ZRQ2_HUMAN,tr|A0A1X7SBZ2|A0A1X7SBZ2_HUMAN" 3 1464.6833 1.01 115312 10864 2 1464.682934 733.3489 Probable ATP-dependent RNA helicase DDX17 OS=Homo sapiens OX=9606 GN=DDX17 PE=1 SV=2 9.47 2152.4 - 293295 - - - -0.2185 - 3.013 0.575 - 870.3 1 2 0 -0.0003 14 0 0 0 2.58E+08 2.55E+08 - - - 6.0556 1 221125_WJC_METTL3_EV_vs_WT_F08.10867.10867.3 6.74E-05 14/60 R.ASGNYATVISHNPETK.K "sp|P62917|RL8_HUMAN,tr|G3V1A1|G3V1A1_HUMAN,tr|E9PKZ0|E9PKZ0_HUMAN" 3 1687.8166 0.99 115313 10867 3 1687.81612 563.6128 60S ribosomal protein L8 OS=Homo sapiens OX=9606 GN=RPL8 PE=1 SV=2 6.79 2152.8 - 9.78E+06 - - - -0.2625 - 3.084 0.487 - 265.4 1 2 0 -0.0004 16 0 0 0 1.57E+08 1.58E+08 - - - 6.8592 1 221125_WJC_METTL3_EV_vs_WT_F08.10870.10870.2 2.61E-08 14/26 R.SSQSSSQQFSGIGR.S "sp|Q92841|DDX17_HUMAN,tr|A0A5H1ZRQ2|A0A5H1ZRQ2_HUMAN,tr|A0A1X7SBZ2|A0A1X7SBZ2_HUMAN" 3 1454.675 1.01 115316 10870 2 1454.67478 728.3448 Probable ATP-dependent RNA helicase DDX17 OS=Homo sapiens OX=9606 GN=DDX17 PE=1 SV=2 9.47 2153.1 - 566553 - - - -0.1402 - 2.867 0.664 - 676 1 2 0 -0.0002 14 0 0 0 2.58E+08 2.55E+08 - - - 6.5884 1 221125_WJC_METTL3_EV_vs_WT_F08.10871.10871.3 7.41E-06 14/52 R.RANENSNIQVLSER.S sp|Q6UN15|FIP1_HUMAN 1 1628.823 0.67 115317 10871 3 1628.824236 543.9483 Pre-mRNA 3'-end-processing factor FIP1 OS=Homo sapiens OX=9606 GN=FIP1L1 PE=1 SV=1 6.14 2153.2 - 526593 - - - 0.7306 - 3.13 0.539 - 369.9 1 2 0 0.0012 14 0 0 0 7.15E+06 1.06E+07 - - - 7.5813 1 221125_WJC_METTL3_EV_vs_WT_F08.10873.10873.2 4.68E-11 30-Oct R.ASGNYATVISHNPETK[136.11].K "sp|P62917|RL8_HUMAN,tr|G3V1A1|G3V1A1_HUMAN,tr|E9PKZ0|E9PKZ0_HUMAN" 3 1695.8308 2.34 115319 10873 2 1695.829452 848.9227 60S ribosomal protein L8 OS=Homo sapiens OX=9606 GN=RPL8 PE=1 SV=2 6.79 2153.5 - 324087 - - - -0.7731 - 2.636 0.67 - 316.5 1 2 0 -0.0013 16 0 0 0 2.24E+07 9.58E+06 - - - 6.3722 1 221125_WJC_METTL3_EV_vs_WT_F08.10877.10877.2 9.90E-06 14/28 K.HGSYEDAVHSGALND.- "sp|P17987|TCPA_HUMAN,tr|F5H282|F5H282_HUMAN,tr|E7EQR6|E7EQR6_HUMAN" 3 1570.6648 - 115323 10877 2 1570.670689 786.3397 T-complex protein 1 subunit alpha OS=Homo sapiens OX=9606 GN=TCP1 PE=1 SV=1 4.72 2154 - 261432 - - - 3.7405 - 2.348 0.632 - 325.5 1 2 0 0.0059 15 0 0 0 - - - - - 5.8056 1 221125_WJC_METTL3_EV_vs_WT_F08.10883.10883.3 3.93E-09 19/64 R.ATSLGR[166.11]PEEEEDELAHR[166.11].C "sp|P36551|HEM6_HUMAN,tr|D6RER6|D6RER6_HUMAN" 2 1957.9244 1.39 115327 10883 3 1957.922771 653.6488 "Oxygen-dependent coproporphyrinogen-III oxidase, mitochondrial OS=Homo sapiens OX=9606 GN=CPOX PE=1 SV=3" 4.41 2154.7 - 1.20E+06 - - - -0.8514 - 3.152 0.6 - 442 1 2 0 -0.0017 17 0 0 0 3.90E+07 2.81E+07 - - - 8.1292 0.9997 221125_WJC_METTL3_EV_vs_WT_F08.10887.10887.4 0.00198 13/90 R.SFGTEDR[166.11]PTDR[166.11]PIPPR[166.11].D "sp|Q8ND56|LS14A_HUMAN,tr|I3L4Q1|I3L4Q1_HUMAN,tr|A0A140TA76|A0A140TA76_HUMAN,tr|K7EMZ9|K7EMZ9_HUMAN" 4 1869.9476 1.33 115331 10887 4 1869.950536 468.4942 Protein LSM14 homolog A OS=Homo sapiens OX=9606 GN=LSM14A PE=1 SV=3 5.84 2155.1 - 384548 - - - 1.5861 - 1.832 0.372 - 97.1 1 2 0 0.003 16 0 0 0 1.20E+07 9.05E+06 - - - 2.6763 1 221125_WJC_METTL3_EV_vs_WT_F08.10891.10891.3 9.56E-07 Nov-60 R.DGQVINETSQHHDDLE.- sp|P08670|VIME_HUMAN 1 1835.7922 - 115334 10891 3 1835.793997 612.938 Vimentin OS=Homo sapiens OX=9606 GN=VIM PE=1 SV=4 4.28 2155.6 - 1.14E+06 - - - 0.9794 - 2.33 0.546 - 156.6 1 2 0 0.0018 16 0 0 0 - - - - - 6.7972 1 221125_WJC_METTL3_EV_vs_WT_F08.10893.10893.4 6.89E-05 Nov-78 K.YDEELEGER[166.11]PHSFR[166.11].L sp|O43290|SNUT1_HUMAN 1 1782.8076 2.11 115335 10893 4 1782.807083 446.7092 U4\U6.U5 tri-snRNP-associated protein 1 OS=Homo sapiens OX=9606 GN=SART1 PE=1 SV=1 4.57 2155.8 - 515725 - - - -0.2995 - 1.991 0.506 - 66.7 1 2 0 -0.0005 14 0 0 0 2.53E+07 1.20E+07 - - - 3.8807 0.9997 221125_WJC_METTL3_EV_vs_WT_F08.10894.10894.3 0.0151 16/48 K.R[166.11]R[166.11]PEPIIPVTQPR[166.11].L "sp|Q92797|SYMPK_HUMAN,tr|A0A087WUE9|A0A087WUE9_HUMAN,tr|M0R3C7|M0R3C7_HUMAN" 3 1587.9352 0.89 115336 10894 3 1587.936887 530.319 Symplekin OS=Homo sapiens OX=9606 GN=SYMPK PE=1 SV=2 11.7 2155.9 - 865996 - - - 1.0907 - 2.475 0.305 - 331.3 1 2 0 0.0017 13 0 0 0 7.09E+06 7.93E+06 - - - 4.3971 1 221125_WJC_METTL3_EV_vs_WT_F08.10895.10895.3 1.11E-06 16/76 K.MEEESGAPGVPSGNGAPGPK.G "sp|P52272|HNRPM_HUMAN,tr|M0R019|M0R019_HUMAN,tr|M0R0Y6|M0R0Y6_HUMAN,tr|M0R0N3|M0R0N3_HUMAN,tr|A0A087X0X3|A0A087X0X3_HUMAN,tr|M0QYQ7|M0QYQ7_HUMAN,tr|M0R2T0|M0R2T0_HUMAN" 7 1866.8418 2.38 115337 10895 3 1866.845613 623.2879 Heterogeneous nuclear ribonucleoprotein M OS=Homo sapiens OX=9606 GN=HNRNPM PE=1 SV=3 4.25 2156.1 - 782494 - - - 2.0468 - 2.226 0.578 - 229.1 1 2 0 0.0038 20 0 0 0 5.33E+07 2.24E+07 - - - 6.9244 0.9999 221125_WJC_METTL3_EV_vs_WT_F08.10896.10896.3 0.0419 Dec-52 K.YDEELEGERPHSFR.L sp|O43290|SNUT1_HUMAN 1 1762.7911 2.74 115338 10896 3 1762.790929 588.6043 U4\U6.U5 tri-snRNP-associated protein 1 OS=Homo sapiens OX=9606 GN=SART1 PE=1 SV=1 4.57 2156.2 - 734111 - - - -0.084 - 2.326 0.436 - 173.1 1 2 0 -0.0001 14 0 0 0 1.50E+07 5.47E+06 - - - 5.6443 1 221125_WJC_METTL3_EV_vs_WT_F08.10900.10900.2 5.08E-10 15/38 K.MEEESGAPGVPSGNGAPGPK[136.11].G "sp|P52272|HNRPM_HUMAN,tr|M0R019|M0R019_HUMAN,tr|M0R0Y6|M0R0Y6_HUMAN,tr|M0R0N3|M0R0N3_HUMAN,tr|A0A087X0X3|A0A087X0X3_HUMAN,tr|M0QYQ7|M0QYQ7_HUMAN,tr|M0R2T0|M0R2T0_HUMAN" 7 1874.856 2.23 115342 10900 2 1874.855101 938.4353 Heterogeneous nuclear ribonucleoprotein M OS=Homo sapiens OX=9606 GN=HNRNPM PE=1 SV=3 4.25 2156.7 - 351994 - - - -0.4752 - 2.928 0.736 - 396.5 1 2 0 -0.0009 20 0 0 0 5.24E+07 2.35E+07 - - - 7.1181 1 221125_WJC_METTL3_EV_vs_WT_F08.10901.10901.3 1.29E-10 14/76 K.MEEESGAPGVPSGNGAPGPK[136.11].G "sp|P52272|HNRPM_HUMAN,tr|M0R019|M0R019_HUMAN,tr|M0R0Y6|M0R0Y6_HUMAN,tr|M0R0N3|M0R0N3_HUMAN,tr|A0A087X0X3|A0A087X0X3_HUMAN,tr|M0QYQ7|M0QYQ7_HUMAN,tr|M0R2T0|M0R2T0_HUMAN" 7 1874.856 2.38 115343 10901 3 1874.855872 625.9593 Heterogeneous nuclear ribonucleoprotein M OS=Homo sapiens OX=9606 GN=HNRNPM PE=1 SV=3 4.25 2156.8 - 341293 - - - -0.064 - 2.68 0.628 - 194.7 1 2 0 -0.0001 20 0 0 0 5.33E+07 2.24E+07 - - - 7.9332 0.9999 221125_WJC_METTL3_EV_vs_WT_F08.10904.10904.4 0.00224 13/96 R.ATSLGR[166.11]PEEEEDELAHR[166.11].C "sp|P36551|HEM6_HUMAN,tr|D6RER6|D6RER6_HUMAN" 2 1957.9244 1.43 115344 10904 4 1957.924254 490.4884 "Oxygen-dependent coproporphyrinogen-III oxidase, mitochondrial OS=Homo sapiens OX=9606 GN=CPOX PE=1 SV=3" 4.41 2157.2 - 4.03E+06 - - - -0.094 - 2.263 0.451 - 159.7 1 2 0 -0.0002 17 0 0 0 7.00E+07 4.90E+07 - - - 3.435 0.9999 221125_WJC_METTL3_EV_vs_WT_F08.10905.10905.4 3.05E-06 Dec-78 K.YDEELEGERPHSFR.L sp|O43290|SNUT1_HUMAN 1 1762.7911 2.08 115345 10905 4 1762.791099 441.705 U4\U6.U5 tri-snRNP-associated protein 1 OS=Homo sapiens OX=9606 GN=SART1 PE=1 SV=1 4.57 2157.3 - 1.76E+06 - - - 0.0125 - 2.391 0.397 - 99.6 1 2 0 0 14 0 0 0 2.53E+07 1.21E+07 - - - 2.9987 0.8826 221125_WJC_METTL3_EV_vs_WT_F08.10908.10908.4 0.313 Dec-84 K.DIK[136.11]PAATHHYLVVPK[136.11].K sp|Q9NQE9|HINT3_HUMAN 1 1703.9694 0.48 115348 10908 4 1703.970105 426.9996 Adenosine 5'-monophosphoramidase HINT3 OS=Homo sapiens OX=9606 GN=HINT3 PE=1 SV=1 8.51 2157.6 - 720017 - - - 0.4278 - 1.339 0.115 - 75.4 1 2 0 0.0007 15 0 0 0 5.77E+06 1.21E+07 - - - 0.3312 0.9978 221125_WJC_METTL3_EV_vs_WT_F08.10912.10912.3 6.54E-06 Nov-56 R.NSDHGEDEVIAVSEK[136.11].V "sp|Q14865|ARI5B_HUMAN,tr|A0A7P0TAD2|A0A7P0TAD2_HUMAN,tr|A0A2R8Y5F2|A0A2R8Y5F2_HUMAN" 3 1635.7468 1.34 115352 10912 3 1636.745571 546.2562 AT-rich interactive domain-containing protein 5B OS=Homo sapiens OX=9606 GN=ARID5B PE=1 SV=3 4.17 2158.1 - 220198 - - - 610.6153 - 2.486 0.55 - 201.3 1 2 0 0.9988 15 0 0 0 7.32E+06 5.48E+06 - - - 6.7716 1 221125_WJC_METTL3_EV_vs_WT_F08.10918.10918.3 1.73E-09 15/56 R.K[136.11]IQVLQQQADDAEER[166.11].A "tr|Q5VU61|Q5VU61_HUMAN,tr|A0A087WWU8|A0A087WWU8_HUMAN,tr|D6R904|D6R904_HUMAN" 3 1787.9133 1.05 115355 10918 3 1787.911924 596.9784 Tropomyosin alpha-3 chain OS=Homo sapiens OX=9606 GN=TPM3 PE=1 SV=3 4.32 2158.8 - 1.72E+06 - - - -0.7478 - 3.465 0.595 - 419.7 1 2 0 -0.0013 15 0 0 0 4.53E+07 4.33E+07 - - - 8.416 1 221125_WJC_METTL3_EV_vs_WT_F08.10924.10924.3 3.56E-09 18/56 R.KIQVLQQQADDAEER.A "tr|Q5VU61|Q5VU61_HUMAN,tr|A0A087WWU8|A0A087WWU8_HUMAN,tr|D6R904|D6R904_HUMAN" 3 1769.8908 1.05 115358 10924 3 1769.89053 590.9709 Tropomyosin alpha-3 chain OS=Homo sapiens OX=9606 GN=TPM3 PE=1 SV=3 4.32 2159.6 - 2.21E+06 - - - -0.1475 - 3.336 0.642 - 671.8 1 2 0 -0.0003 15 0 0 0 4.53E+07 4.33E+07 - - - 8.8413 0.9999 221125_WJC_METTL3_EV_vs_WT_F08.10928.10928.3 0.000102 Sep-56 R.R[166.11]ILELSGSSSEDSEK[136.11].V sp|P78527|PRKDC_HUMAN 1 1653.8176 0.1 115362 10928 3 1653.817779 552.2798 DNA-dependent protein kinase catalytic subunit OS=Homo sapiens OX=9606 GN=PRKDC PE=1 SV=3 4.41 2160 - 269544 - - - 0.0907 - 2.13 0.449 - 89.4 1 2 0 0.0001 15 0 0 0 1.92E+05 2.00E+06 - - - 5.5189 1 221125_WJC_METTL3_EV_vs_WT_F08.10930.10930.2 1.06E-07 30-Oct K.STAGDTHLGGEDFDNR[166.11].M "sp|P54652|HSP72_HUMAN,sp|P11142|HSP7C_HUMAN,tr|E9PKE3|E9PKE3_HUMAN,tr|E9PN89|E9PN89_HUMAN" 4 1700.7266 0.001 115364 10930 2 1700.72562 851.3706 Heat shock-related 70 kDa protein 2 OS=Homo sapiens OX=9606 GN=HSPA2 PE=1 SV=1 4.22 2160.3 - 223891 - - - -0.5621 - 2.323 0.689 - 205.8 1 2 0 -0.001 16 0 0 0 0.00E+00 5.74E+06 - - - 6.2019 0.9991 221125_WJC_METTL3_EV_vs_WT_F08.10937.10937.3 0.0164 Nov-48 K.NPSDSAVHSPFTK[136.11].R "sp|Q14157|UBP2L_HUMAN,tr|F8W726|F8W726_HUMAN" 2 1393.6717 6.03 115369 10937 3 1393.672114 465.5645 Ubiquitin-associated protein 2-like OS=Homo sapiens OX=9606 GN=UBAP2L PE=1 SV=2 6.74 2161.2 - 729208 - - - 0.2662 - 1.713 0.307 - 116.4 1 2 0 0.0004 13 0 0 0 1.15E+08 1.90E+07 - - - 3.422 1 221125_WJC_METTL3_EV_vs_WT_F08.10942.10942.2 1.04E-07 28-Dec R.KIQVLQQQADDAEER.A "tr|Q5VU61|Q5VU61_HUMAN,tr|A0A087WWU8|A0A087WWU8_HUMAN,tr|D6R904|D6R904_HUMAN" 3 1769.8908 1.39 115374 10942 2 1769.890999 885.9527 Tropomyosin alpha-3 chain OS=Homo sapiens OX=9606 GN=TPM3 PE=1 SV=3 4.32 2161.9 - 183209 - - - 0.1175 - 2.814 0.636 - 421.3 1 2 0 0.0002 15 0 0 0 3.13E+06 2.25E+06 - - - 6.2821 1 221125_WJC_METTL3_EV_vs_WT_F08.10949.10949.3 1.45E-10 20/72 K.VVQVSAGDSHTAALTDDGR[166.11].V "sp|P18754|RCC1_HUMAN,tr|C9JQZ4|C9JQZ4_HUMAN,tr|C9J3R0|C9J3R0_HUMAN,tr|C9JMJ4|C9JMJ4_HUMAN,tr|C9JW69|C9JW69_HUMAN,tr|C9JRH2|C9JRH2_HUMAN" 6 1907.9213 0.88 115379 10949 3 1907.916051 636.981 Regulator of chromosome condensation OS=Homo sapiens OX=9606 GN=RCC1 PE=1 SV=1 4.41 2162.6 - 782684 - - - -2.7265 - 4.064 0.64 - 481.6 1 2 0 -0.0052 19 0 0 0 1.02E+07 1.15E+07 - - - 9.1188 0.9997 221125_WJC_METTL3_EV_vs_WT_F08.10956.10956.3 0.00011 14/48 K.ATFIK[136.11]VPQNQNGK[136.11].S "sp|P19338|NUCL_HUMAN,tr|A0A7I2V506|A0A7I2V506_HUMAN,tr|A0A7I2V699|A0A7I2V699_HUMAN,tr|A0A7I2V2U7|A0A7I2V2U7_HUMAN,tr|A0A7I2V3F3|A0A7I2V3F3_HUMAN,tr|A0A7I2V428|A0A7I2V428_HUMAN,tr|A0A7I2V349|A0A7I2V349_HUMAN,tr|H7BY16|H7BY16_HUMAN,tr|A0A7I2V5M5|A0A7I2V5M5_HUMAN,tr|C9JLB1|C9JLB1_HUMAN" 10 1459.8118 0.97 115384 10956 3 1459.811058 487.6112 Nucleolin OS=Homo sapiens OX=9606 GN=NCL PE=1 SV=3 10 2163.4 - 882655 - - - -0.5172 - 2.345 0.415 - 209.5 1 2 1 -0.0008 13 0 0 0 4.64E+07 4.76E+07 - - - 5.4774 1 221125_WJC_METTL3_EV_vs_WT_F08.10957.10957.3 2.62E-11 20/72 K.VVQVSAGDSHTAALTDDGR.V "sp|P18754|RCC1_HUMAN,tr|C9JQZ4|C9JQZ4_HUMAN,tr|C9J3R0|C9J3R0_HUMAN,tr|C9JMJ4|C9JMJ4_HUMAN,tr|C9JW69|C9JW69_HUMAN,tr|C9JRH2|C9JRH2_HUMAN" 6 1897.913 0.88 115385 10957 3 1897.917327 633.6449 Regulator of chromosome condensation OS=Homo sapiens OX=9606 GN=RCC1 PE=1 SV=1 4.41 2163.6 - 740372 - - - 2.2888 - 3.894 0.682 - 505.6 1 2 0 0.0043 19 0 0 0 1.02E+07 1.15E+07 - - - 9.4823 1 221125_WJC_METTL3_EV_vs_WT_F08.10962.10962.2 8.11E-10 16/32 R.ASAQQENSSTC[160.03]IGSAIK[136.11].S sp|Q9NXV6|CARF_HUMAN 1 1758.8298 1.16 115390 10962 2 1758.831532 880.4222 CDKN2A-interacting protein OS=Homo sapiens OX=9606 GN=CDKN2AIP PE=1 SV=3 6.04 2164.2 - 169600 - - - 0.9978 - 3.33 0.693 - 893.8 1 2 0 0.0018 17 0 0 0 3.51E+06 3.03E+06 - - - 7.1165 1 221125_WJC_METTL3_EV_vs_WT_F08.10964.10964.2 4.41E-12 17/32 R.ASAQQENSSTC[160.03]IGSAIK.S sp|Q9NXV6|CARF_HUMAN 1 1750.8156 1.16 115392 10964 2 1750.817735 876.4151 CDKN2A-interacting protein OS=Homo sapiens OX=9606 GN=CDKN2AIP PE=1 SV=3 6.04 2164.5 - 131228 - - - 1.2326 - 3.397 0.691 - 1092.1 1 2 0 0.0022 17 0 0 0 3.51E+06 3.03E+06 - - - 7.1506 0.983 221125_WJC_METTL3_EV_vs_WT_F08.10967.10967.3 0.000108 14/48 F.TNQGTVIHFNNPK[136.11].V "sp|P20290|BTF3_HUMAN,tr|A0A7I2V3T6|A0A7I2V3T6_HUMAN,tr|D6RDG3|D6RDG3_HUMAN,tr|A0A7I2V5Y3|A0A7I2V5Y3_HUMAN,tr|H0Y9Y1|H0Y9Y1_HUMAN,tr|A0A7I2YQL2|A0A7I2YQL2_HUMAN" 6 1476.7565 1.03 115393 10967 3 1476.758509 493.2594 Transcription factor BTF3 OS=Homo sapiens OX=9606 GN=BTF3 PE=1 SV=1 8.44 2164.9 - 1.15E+06 - - - 1.3767 - 2.801 0.329 - 394.7 1 1 0 0.002 13 0 0 0 1.95E+07 1.90E+07 - - - 5 0.826 221125_WJC_METTL3_EV_vs_WT_F08.10968.10968.4 0.000614 Dec-90 K.IK[136.11]ELTSTC[160.03]SPIISK[136.11]PK[136.11].P sp|P34932|HSP74_HUMAN 1 1825.0445 0.1 115394 10968 4 1825.0463 457.2684 Heat shock 70 kDa protein 4 OS=Homo sapiens OX=9606 GN=HSPA4 PE=1 SV=4 9.2 2165 - 1.06E+06 - - - 0.9742 - 2.234 0.334 - 105.4 1 1 1 0.0018 16 0 0 0 1.67E+06 1.72E+07 - - - 2.4158 0.9855 221125_WJC_METTL3_EV_vs_WT_F08.10969.10969.3 0.0213 Dec-48 F.TNQGTVIHFNNPK.V "sp|P20290|BTF3_HUMAN,tr|A0A7I2V3T6|A0A7I2V3T6_HUMAN,tr|D6RDG3|D6RDG3_HUMAN,tr|A0A7I2V5Y3|A0A7I2V5Y3_HUMAN,tr|H0Y9Y1|H0Y9Y1_HUMAN,tr|A0A7I2YQL2|A0A7I2YQL2_HUMAN" 6 1468.7423 1.04 115395 10969 3 1468.743913 490.588 Transcription factor BTF3 OS=Homo sapiens OX=9606 GN=BTF3 PE=1 SV=1 8.44 2165.1 - 1.16E+06 - - - 1.1146 - 2.435 0.365 - 270 1 1 0 0.0016 13 0 0 0 1.94E+07 1.88E+07 - - - 5.0218 1 221125_WJC_METTL3_EV_vs_WT_F08.10972.10972.3 3.77E-06 14/60 K.ATAGDTHLGGEDFDNR.L "sp|P48741|HSP77_HUMAN,sp|P0DMV8|HS71A_HUMAN,sp|P34931|HS71L_HUMAN,sp|P0DMV9|HS71B_HUMAN,sp|P17066|HSP76_HUMAN,tr|Q53FA3|Q53FA3_HUMAN,tr|V9GZ37|V9GZ37_HUMAN,tr|A0A0G2JIW1|A0A0G2JIW1_HUMAN" 8 1674.7234 0.13 115398 10972 3 1674.72661 559.2484 Putative heat shock 70 kDa protein 7 OS=Homo sapiens OX=9606 GN=HSPA7 PE=5 SV=2 4.22 2165.3 - 553067 - - - 1.9221 - 2.853 0.612 - 279.3 1 2 0 0.0032 16 0 0 0 2.42E+07 1.82E+08 - - - 8.0523 0.9871 221125_WJC_METTL3_EV_vs_WT_F08.10973.10973.3 6.92E-08 Nov-60 K.IK[136.11]ELTSTC[160.03]SPIISK[136.11]PK[136.11].P sp|P34932|HSP74_HUMAN 1 1825.0445 0.01 115399 10973 3 1825.047272 609.3555 Heat shock 70 kDa protein 4 OS=Homo sapiens OX=9606 GN=HSPA4 PE=1 SV=4 9.2 2165.4 - 487056 - - - 1.5068 - 2.476 0.564 - 86.2 1 1 1 0.0027 16 0 0 0 1.34E+05 9.27E+06 - - - 7.1536 0.9869 221125_WJC_METTL3_EV_vs_WT_F08.10978.10978.4 0.00269 Aug-78 R.GHYNNVSC[160.03]AVFHPR.Q "sp|P53621|COPA_HUMAN,tr|A0A3B3ISC6|A0A3B3ISC6_HUMAN,tr|A0A3B3ITV3|A0A3B3ITV3_HUMAN,tr|A0A3B3IS84|A0A3B3IS84_HUMAN,tr|A0A3B3IU89|A0A3B3IU89_HUMAN,tr|A0A3B3ISK1|A0A3B3ISK1_HUMAN,tr|A0A3B3IT15|A0A3B3IT15_HUMAN" 7 1656.7579 0.54 115404 10978 4 1657.759552 415.1968 Coatomer subunit alpha OS=Homo sapiens OX=9606 GN=COPA PE=1 SV=2 8.24 2166.1 - 305961 - - - 604.5596 - 1.51 0.375 - 43.7 1 2 0 1.0016 14 0 0 0 3.29E+06 6.13E+06 - - - 2.3625 0.996 221125_WJC_METTL3_EV_vs_WT_F08.10979.10979.3 0.056 Apr-72 K.MTTETASEDDNFGTAQSNK.A sp|Q92616|GCN1_HUMAN 1 2045.8484 0.7 115405 10979 3 2045.853756 682.9567 eIF-2-alpha kinase activator GCN1 OS=Homo sapiens OX=9606 GN=GCN1 PE=1 SV=6 3.92 2166.2 - 118493 - - - 2.6214 - 1.037 0.4 - 13.9 1 2 0 0.0054 19 0 0 0 8.03E+05 1.15E+06 - - - 3.0874 1 221125_WJC_METTL3_EV_vs_WT_F08.10982.10982.3 2.30E-08 13/60 K.STAGDTHLGGEDFDNR[166.11].M "sp|P54652|HSP72_HUMAN,sp|P11142|HSP7C_HUMAN,tr|E9PKE3|E9PKE3_HUMAN,tr|E9PN89|E9PN89_HUMAN" 4 1700.7266 0.18 115407 10982 3 1700.728502 567.9161 Heat shock-related 70 kDa protein 2 OS=Homo sapiens OX=9606 GN=HSPA2 PE=1 SV=1 4.22 2166.6 - 4.83E+06 - - - 1.1325 - 2.75 0.615 - 240.2 1 2 0 0.0019 16 0 0 0 3.97E+07 2.16E+08 - - - 7.9917 0.9935 221125_WJC_METTL3_EV_vs_WT_F08.10984.10984.3 0.205 Oct-48 K.ATFIKVPQNQNGK.S "sp|P19338|NUCL_HUMAN,tr|A0A7I2V506|A0A7I2V506_HUMAN,tr|A0A7I2V699|A0A7I2V699_HUMAN,tr|A0A7I2V2U7|A0A7I2V2U7_HUMAN,tr|A0A7I2V3F3|A0A7I2V3F3_HUMAN,tr|A0A7I2V428|A0A7I2V428_HUMAN,tr|A0A7I2V349|A0A7I2V349_HUMAN,tr|H7BY16|H7BY16_HUMAN,tr|A0A7I2V5M5|A0A7I2V5M5_HUMAN,tr|C9JLB1|C9JLB1_HUMAN" 10 1443.7834 0.97 115408 10984 3 1443.78675 482.2684 Nucleolin OS=Homo sapiens OX=9606 GN=NCL PE=1 SV=3 10 2166.8 - 2.61E+06 - - - 2.3113 - 2.026 0.29 - 103.7 1 2 1 0.0033 13 0 0 0 4.64E+07 4.76E+07 - - - 3.6866 0.9973 221125_WJC_METTL3_EV_vs_WT_F08.10991.10991.2 0.000173 24-Aug K.ATFIK[136.11]VPQNQNGK[136.11].S "sp|P19338|NUCL_HUMAN,tr|A0A7I2V506|A0A7I2V506_HUMAN,tr|A0A7I2V699|A0A7I2V699_HUMAN,tr|A0A7I2V2U7|A0A7I2V2U7_HUMAN,tr|A0A7I2V3F3|A0A7I2V3F3_HUMAN,tr|A0A7I2V428|A0A7I2V428_HUMAN,tr|A0A7I2V349|A0A7I2V349_HUMAN,tr|H7BY16|H7BY16_HUMAN,tr|A0A7I2V5M5|A0A7I2V5M5_HUMAN,tr|C9JLB1|C9JLB1_HUMAN" 10 1459.8118 0.94 115415 10991 2 1459.811139 730.9132 Nucleolin OS=Homo sapiens OX=9606 GN=NCL PE=1 SV=3 10 2167.6 - 181483 - - - -0.4617 - 1.617 0.486 - 124.4 1 2 1 -0.0007 13 0 0 0 1.85E+06 1.98E+06 - - - 3.8638 0.9999 221125_WJC_METTL3_EV_vs_WT_F08.10995.10995.3 7.03E-05 Oct-60 K.NLTEQNSYSNIPHEGK[136.11].H "sp|Q5T035|CI129_HUMAN,sp|Q9NZB2|F120A_HUMAN,tr|A0A0C4DH52|A0A0C4DH52_HUMAN" 3 1837.8686 1.01 115417 10995 3 1837.870399 613.6301 Putative uncharacterized protein C9orf129 OS=Homo sapiens OX=9606 GN=C9orf129 PE=4 SV=1 5.4 2168.1 - 989234 - - - 0.9761 - 2.063 0.475 - 97.9 1 2 0 0.0018 16 0 0 0 3.36E+07 3.34E+07 - - - 5.6934 0.9999 221125_WJC_METTL3_EV_vs_WT_F08.10996.10996.4 1.91E-06 17/114 K.GVLNVHPAASASK[136.11]PSADQIR[166.11].Q "sp|Q92576|PHF3_HUMAN,tr|E7ER40|E7ER40_HUMAN,tr|E7EVH3|E7EVH3_HUMAN" 3 2035.093 1.38 115418 10996 4 2035.094938 509.7805 PHD finger protein 3 OS=Homo sapiens OX=9606 GN=PHF3 PE=1 SV=3 8.75 2168.3 - 503875 - - - 0.9734 - 3.211 0.436 - 151.7 1 2 0 0.002 20 0 0 0 1.87E+07 1.36E+07 - - - 3.4104 0.9785 221125_WJC_METTL3_EV_vs_WT_F08.10997.10997.3 0.00334 Aug-60 K.NLTEQNSYSNIPHEGK.H "sp|Q5T035|CI129_HUMAN,sp|Q9NZB2|F120A_HUMAN,tr|A0A0C4DH52|A0A0C4DH52_HUMAN" 3 1829.8544 1.01 115419 10997 3 1829.854797 610.9587 Putative uncharacterized protein C9orf129 OS=Homo sapiens OX=9606 GN=C9orf129 PE=4 SV=1 5.4 2168.3 - 723948 - - - 0.2142 - 1.722 0.127 - 61.7 1 2 0 0.0004 16 0 0 0 3.36E+07 3.34E+07 - - - 1.3503 0.9914 221125_WJC_METTL3_EV_vs_WT_F08.11000.11000.4 1.68E-07 18/96 R.PLHPPPPPPVQPPQHPR.A "sp|Q9UKV3|ACINU_HUMAN,tr|G3V3B0|G3V3B0_HUMAN,tr|S4R3H4|S4R3H4_HUMAN,tr|E7EQT4|E7EQT4_HUMAN" 4 1887.0268 1.96 115422 11000 4 1887.031625 472.764 Apoptotic chromatin condensation inducer in the nucleus OS=Homo sapiens OX=9606 GN=ACIN1 PE=1 SV=2 10.18 2168.7 - 357221 - - - 2.5723 - 2.917 0.507 - 296.6 1 1 0 0.0049 17 0 0 0 1.19E+07 6.06E+06 - - - 4.0093 1 221125_WJC_METTL3_EV_vs_WT_F08.11006.11006.3 2.39E-08 13/68 R.ETVAVK[136.11]PTENNEEEFTSK[136.11].D "sp|O60841|IF2P_HUMAN,tr|A0A087WUT6|A0A087WUT6_HUMAN" 2 2066.9979 0.52 115426 11006 3 2066.999949 690.0066 Eukaryotic translation initiation factor 5B OS=Homo sapiens OX=9606 GN=EIF5B PE=1 SV=4 4.33 2169.5 - 472573 - - - 0.9937 - 2.776 0.578 - 206.8 1 2 0 0.0021 18 0 0 0 3.93E+06 7.59E+06 - - - 7.526 0.9994 221125_WJC_METTL3_EV_vs_WT_F08.11008.11008.2 2.03E-09 Dec-32 R.ATGGGLSSVGGGSSTIK.Y sp|P04259|K2C6B_HUMAN 1 1434.7314 999 115428 11008 2 1434.736447 718.373 "Keratin, type II cytoskeletal 6B OS=Homo sapiens OX=9606 GN=KRT6B PE=1 SV=5" 8.8 2169.8 - 287537 - - - 3.4919 - 2.486 0.591 - 338.5 1 2 0 0.005 17 0 0 0 2.37E+06 0.00E+00 - - - 5.6435 1 221125_WJC_METTL3_EV_vs_WT_F08.11009.11009.2 1.19E-08 Nov-36 R.SDSPVPTAPTSGGPK[136.11]PSTA.S "sp|Q86U44|MTA70_HUMAN,tr|B4E349|B4E349_HUMAN,tr|F5H6D8|F5H6D8_HUMAN,tr|B4DTN4|B4DTN4_HUMAN" 4 1760.8672 0.03 115429 11009 2 1760.871983 881.4409 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 5.55 2169.9 - 222506 - - - 2.7117 - 2.403 0.649 - 165.4 1 1 0 0.0048 19 0 0 0 4.65E+07 1.51E+09 - - - 5.9885 1 221125_WJC_METTL3_EV_vs_WT_F08.11012.11012.2 5.47E-07 26-Nov T.AGDTHLGGEDFDNR[166.11].L "sp|P48741|HSP77_HUMAN,sp|P54652|HSP72_HUMAN,sp|P0DMV8|HS71A_HUMAN,sp|P34931|HS71L_HUMAN,sp|P11142|HSP7C_HUMAN,sp|P0DMV9|HS71B_HUMAN,sp|P17066|HSP76_HUMAN,tr|E9PKE3|E9PKE3_HUMAN,tr|E9PN89|E9PN89_HUMAN,tr|Q53FA3|Q53FA3_HUMAN,tr|V9GZ37|V9GZ37_HUMAN,tr|A0A0G2JIW1|A0A0G2JIW1_HUMAN" 12 1512.6469 0.11 115432 11012 2 1512.651215 757.3307 Putative heat shock 70 kDa protein 7 OS=Homo sapiens OX=9606 GN=HSPA7 PE=5 SV=2 4.22 2170.3 - 80411.2 - - - 2.8731 - 2.586 0.64 - 322.6 1 1 0 0.0043 14 0 0 0 2.29E+05 2.03E+06 - - - 6.1509 0.9999 221125_WJC_METTL3_EV_vs_WT_F08.11019.11019.4 4.08E-06 13/78 K.TALDDR[166.11]PQVLQPHR[166.11].L sp|Q9ULJ3|ZBT21_HUMAN 1 1664.8861 0.58 115437 11019 4 1664.887705 417.2288 Zinc finger and BTB domain-containing protein 21 OS=Homo sapiens OX=9606 GN=ZBTB21 PE=1 SV=2 6.41 2171.1 - 316762 - - - 0.9388 - 2.307 0.453 - 151.3 1 2 0 0.0016 14 0 0 0 5.23E+06 9.02E+06 - - - 3.4727 1 221125_WJC_METTL3_EV_vs_WT_F08.11020.11020.3 5.39E-07 18/48 G.R[166.11]AQVQEFC[160.03]DYGTK[136.11].E "sp|Q86U44|MTA70_HUMAN,tr|H0YFV6|H0YFV6_HUMAN" 2 1618.7529 0.05 115438 11020 3 1618.756252 540.5916 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 6.06 2171.2 - 1.06E+06 - - - 2.0948 - 3.166 0.652 - 662.8 1 1 0 0.0034 13 0 0 0 5.11E+06 1.12E+08 - - - 8.9329 0.9996 221125_WJC_METTL3_EV_vs_WT_F08.11021.11021.3 1.38E-06 15/48 K.ASLENSLEETKGR.Y "sp|P02533|K1C14_HUMAN,sp|P08779|K1C16_HUMAN,tr|K7ENW6|K7ENW6_HUMAN" 3 1432.7158 221.33 115439 11021 3 1432.719667 478.5792 "Keratin, type I cytoskeletal 14 OS=Homo sapiens OX=9606 GN=KRT14 PE=1 SV=4" 4.79 2171.4 - 717955 - - - 2.7081 - 3.139 0.432 - 417.2 1 2 1 0.0039 13 0 0 0 1.89E+07 8.54E+04 - - - 6.4568 0.9999 221125_WJC_METTL3_EV_vs_WT_F08.11023.11023.3 6.43E-06 Oct-52 K.DMYNDTLNGSTEKR.S sp|Q96PU8|QKI_HUMAN 1 1642.7257 3.23 115441 11023 3 1642.72839 548.5825 Protein quaking OS=Homo sapiens OX=9606 GN=QKI PE=1 SV=1 4.56 2171.6 - 308151 - - - 1.6381 - 1.917 0.547 - 87 1 2 0 0.0027 14 0 0 0 4.69E+06 1.45E+06 - - - 6.3672 1 221125_WJC_METTL3_EV_vs_WT_F08.11024.11024.3 1.01E-07 13/68 R.ETVAVKPTENNEEEFTSK.D "sp|O60841|IF2P_HUMAN,tr|A0A087WUT6|A0A087WUT6_HUMAN" 2 2050.9695 0.55 115442 11024 3 2050.972 684.6638 Eukaryotic translation initiation factor 5B OS=Homo sapiens OX=9606 GN=EIF5B PE=1 SV=4 4.33 2171.7 - 295786 - - - 1.2214 - 2.868 0.585 - 210.6 1 2 0 0.0025 18 0 0 0 3.93E+06 7.19E+06 - - - 7.6851 0.9845 221125_WJC_METTL3_EV_vs_WT_F08.11025.11025.3 0.00246 Oct-64 K.TTPNSGDVQVTEDAVR[166.11]R[166.11].Y "sp|P35269|T2FA_HUMAN,tr|M0QXD6|M0QXD6_HUMAN" 2 1863.919 1.15 115443 11025 3 1863.930773 622.3136 General transcription factor IIF subunit 1 OS=Homo sapiens OX=9606 GN=GTF2F1 PE=1 SV=2 4.56 2171.9 - 279923 - - - 6.3388 - 2.141 0.319 - 139.9 1 2 0 0.0118 17 0 0 0 9.82E+06 8.55E+06 - - - 4.0165 1 221125_WJC_METTL3_EV_vs_WT_F08.11026.11026.3 1.78E-07 15/76 K.GVLNVHPAASASK[136.11]PSADQIR[166.11].Q "sp|Q92576|PHF3_HUMAN,tr|E7ER40|E7ER40_HUMAN,tr|E7EVH3|E7EVH3_HUMAN" 3 2035.093 1.22 115444 11026 3 2035.094434 679.3716 PHD finger protein 3 OS=Homo sapiens OX=9606 GN=PHF3 PE=1 SV=3 8.75 2172 - 228541 - - - 0.7258 - 3.072 0.492 - 180.2 1 2 0 0.0015 20 0 0 0 2.32E+06 1.90E+06 - - - 6.7477 0.9966 221125_WJC_METTL3_EV_vs_WT_F08.11027.11027.3 0.00053 Sep-64 K.FMSVQR[166.11]PGPYDR[166.11]PGTAR[166.11].R sp|P52597|HNRPF_HUMAN 1 1963.9829 0.68 115445 11027 3 1963.989017 655.6682 Heterogeneous nuclear ribonucleoprotein F OS=Homo sapiens OX=9606 GN=HNRNPF PE=1 SV=3 10.74 2172.1 - 216284 - - - 3.11 - 1.583 0.336 - 28.9 1 2 0 0.0061 17 0 0 0 7.65E+06 1.12E+07 - - - 3.4448 0.998 221125_WJC_METTL3_EV_vs_WT_F08.11032.11032.4 0.000433 15/114 K.GVLNVHPAASASKPSADQIR.Q "sp|Q92576|PHF3_HUMAN,tr|E7ER40|E7ER40_HUMAN,tr|E7EVH3|E7EVH3_HUMAN" 3 2017.0705 1.08 115448 11032 4 2017.075835 505.2749 PHD finger protein 3 OS=Homo sapiens OX=9606 GN=PHF3 PE=1 SV=3 8.75 2172.7 - 843544 - - - 2.6514 - 2.595 0.298 - 120.9 1 2 0 0.0053 20 0 0 0 1.41E+07 1.30E+07 - - - 2.1371 0.9998 221125_WJC_METTL3_EV_vs_WT_F08.11033.11033.4 0.00117 13/72 K.NLDDTIDDEKLRK.E "sp|Q13310|PABP4_HUMAN,tr|A0A7I2V5W9|A0A7I2V5W9_HUMAN,tr|H0YEU6|H0YEU6_HUMAN,tr|B1ANR0|B1ANR0_HUMAN,tr|A0A7I2V4L7|A0A7I2V4L7_HUMAN,tr|A0A7I2V598|A0A7I2V598_HUMAN,tr|H0Y5F5|H0Y5F5_HUMAN" 7 1573.7948 1.41 115449 11033 4 1573.798146 394.456 Polyadenylate-binding protein 4 OS=Homo sapiens OX=9606 GN=PABPC4 PE=1 SV=1 4.36 2172.8 - 447710 - - - 2.1483 - 2.308 0.507 - 176.7 1 2 1 0.0034 13 0 0 0 5.68E+07 4.02E+07 - - - 3.9481 0.9999 221125_WJC_METTL3_EV_vs_WT_F08.11034.11034.4 4.98E-05 17/72 K.NLDDTIDDEK[136.11]LR[166.11]K[136.11].E "sp|Q13310|PABP4_HUMAN,tr|A0A7I2V5W9|A0A7I2V5W9_HUMAN,tr|H0YEU6|H0YEU6_HUMAN,tr|B1ANR0|B1ANR0_HUMAN,tr|A0A7I2V4L7|A0A7I2V4L7_HUMAN,tr|A0A7I2V598|A0A7I2V598_HUMAN,tr|H0Y5F5|H0Y5F5_HUMAN" 7 1599.8314 1.41 115450 11034 4 1599.833459 400.9651 Polyadenylate-binding protein 4 OS=Homo sapiens OX=9606 GN=PABPC4 PE=1 SV=1 4.36 2172.9 - 424544 - - - 1.2651 - 3.016 0.533 - 340.6 1 2 1 0.002 13 0 0 0 5.68E+07 4.02E+07 - - - 4.274 0.9991 221125_WJC_METTL3_EV_vs_WT_F08.11036.11036.3 2.79E-08 18/68 R.TPAPEPEPC[160.03]EASELPAKR.L "sp|Q9ULV3|CIZ1_HUMAN,tr|Q5SYW2|Q5SYW2_HUMAN,tr|F5H2X7|F5H2X7_HUMAN,tr|H0Y5D5|H0Y5D5_HUMAN,tr|A0A494C0L7|A0A494C0L7_HUMAN,tr|Q9BTG3|Q9BTG3_HUMAN" 6 1977.9466 3.71 115452 11036 3 1977.950408 660.3228 Cip1-interacting zinc finger protein OS=Homo sapiens OX=9606 GN=CIZ1 PE=1 SV=2 4.49 2173.2 - 389530 - - - 1.9293 - 3.063 0.227 - 347.7 1 2 0 0.0038 18 0 0 0 3.49E+08 9.40E+07 - - - 3.8572 0.9999 221125_WJC_METTL3_EV_vs_WT_F08.11038.11038.2 1.80E-07 30-Nov K.ATAGDTHLGGEDFDNR[166.11].L "sp|P48741|HSP77_HUMAN,sp|P0DMV8|HS71A_HUMAN,sp|P34931|HS71L_HUMAN,sp|P0DMV9|HS71B_HUMAN,sp|P17066|HSP76_HUMAN,tr|Q53FA3|Q53FA3_HUMAN,tr|V9GZ37|V9GZ37_HUMAN,tr|A0A0G2JIW1|A0A0G2JIW1_HUMAN" 8 1684.7317 0.01 115454 11038 2 1684.732489 843.3731 Putative heat shock 70 kDa protein 7 OS=Homo sapiens OX=9606 GN=HSPA7 PE=5 SV=2 4.22 2173.5 - 185922 - - - 0.4915 - 2.045 0.597 - 308.6 1 2 0 0.0008 16 0 0 0 5.63E+04 7.81E+06 - - - 5.209 0.9977 221125_WJC_METTL3_EV_vs_WT_F08.11041.11041.4 0.0255 Dec-96 K.FMSVQR[166.11]PGPYDR[166.11]PGTAR[166.11].R sp|P52597|HNRPF_HUMAN 1 1963.9829 0.72 115455 11041 4 1963.987624 492.003 Heterogeneous nuclear ribonucleoprotein F OS=Homo sapiens OX=9606 GN=HNRNPF PE=1 SV=3 10.74 2173.9 - 1.75E+06 - - - 2.4007 - 1.851 0.294 - 78.3 1 2 0 0.0047 17 0 0 0 2.82E+07 3.90E+07 - - - 1.9974 0.9999 221125_WJC_METTL3_EV_vs_WT_F08.11043.11043.3 6.34E-05 13/44 R.VDFTNHLEDTRR.N "sp|O75635|SPB7_HUMAN,tr|C9JM00|C9JM00_HUMAN" 2 1501.7274 102.06 115457 11043 3 1501.729579 501.5831 Serpin B7 OS=Homo sapiens OX=9606 GN=SERPINB7 PE=1 SV=1 5.38 2174 - 1.24E+06 - - - 1.4816 - 2.417 0.383 - 360 1 2 0 0.0022 12 0 0 0 1.89E+07 1.85E+05 - - - 5.2557 0.9999 221125_WJC_METTL3_EV_vs_WT_F08.11044.11044.3 3.44E-07 15/48 K.NLDDTIDDEKLRK.E "sp|Q13310|PABP4_HUMAN,tr|A0A7I2V5W9|A0A7I2V5W9_HUMAN,tr|H0YEU6|H0YEU6_HUMAN,tr|B1ANR0|B1ANR0_HUMAN,tr|A0A7I2V4L7|A0A7I2V4L7_HUMAN,tr|A0A7I2V598|A0A7I2V598_HUMAN,tr|H0Y5F5|H0Y5F5_HUMAN" 7 1573.7948 1.64 115458 11044 3 1573.798441 525.6055 Polyadenylate-binding protein 4 OS=Homo sapiens OX=9606 GN=PABPC4 PE=1 SV=1 4.36 2174.1 - 1.16E+06 - - - 2.3358 - 3.183 0.585 - 344.9 1 2 1 0.0037 13 0 0 0 8.53E+07 5.19E+07 - - - 8.2004 0.9995 221125_WJC_METTL3_EV_vs_WT_F08.11045.11045.4 7.39E-05 Nov-84 K.R[166.11]SLDPADER[166.11]DDVLAK[136.11].R "sp|Q8WXI9|P66B_HUMAN,tr|A0A0U1RR34|A0A0U1RR34_HUMAN,tr|A0A0U1RRM1|A0A0U1RRM1_HUMAN,tr|A0A0U1RRK3|A0A0U1RRK3_HUMAN" 4 1726.8844 2.42 115459 11045 4 1726.886784 432.7284 Transcriptional repressor p66-beta OS=Homo sapiens OX=9606 GN=GATAD2B PE=1 SV=1 4.36 2174.3 - 457838 - - - 1.3707 - 2.567 0.407 - 104.4 1 2 1 0.0024 15 0 0 0 2.45E+07 1.01E+07 - - - 3.1052 1 221125_WJC_METTL3_EV_vs_WT_F08.11046.11046.2 3.31E-07 16/24 G.R[166.11]AQVQEFC[160.03]DYGTK[136.11].E "sp|Q86U44|MTA70_HUMAN,tr|H0YFV6|H0YFV6_HUMAN" 2 1618.7529 0.39 115460 11046 2 1618.752426 810.3837 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 6.06 2174.4 - 350383 - - - -0.2687 - 3.137 0.558 - 796.2 1 1 0 -0.0004 13 0 0 0 3.57E+06 9.22E+06 - - - 6.0965 0.9999 221125_WJC_METTL3_EV_vs_WT_F08.11047.11047.3 0.00523 14/68 R.TPAPEPEPC[160.03]EASELPAK[136.11]R[166.11].L "sp|Q9ULV3|CIZ1_HUMAN,tr|Q5SYW2|Q5SYW2_HUMAN,tr|F5H2X7|F5H2X7_HUMAN,tr|H0Y5D5|H0Y5D5_HUMAN,tr|A0A494C0L7|A0A494C0L7_HUMAN,tr|Q9BTG3|Q9BTG3_HUMAN" 6 1995.9691 3.71 115461 11047 3 1995.972819 666.3303 Cip1-interacting zinc finger protein OS=Homo sapiens OX=9606 GN=CIZ1 PE=1 SV=2 4.49 2174.5 - 285330 - - - 1.8823 - 2.721 0.43 - 246.5 1 2 0 0.0038 18 0 0 0 3.49E+08 9.40E+07 - - - 5.8256 0.9999 221125_WJC_METTL3_EV_vs_WT_F08.11052.11052.3 6.55E-08 15/48 K.NLDDTIDDEK[136.11]LR[166.11]K[136.11].E "sp|Q13310|PABP4_HUMAN,tr|A0A7I2V5W9|A0A7I2V5W9_HUMAN,tr|H0YEU6|H0YEU6_HUMAN,tr|B1ANR0|B1ANR0_HUMAN,tr|A0A7I2V4L7|A0A7I2V4L7_HUMAN,tr|A0A7I2V598|A0A7I2V598_HUMAN,tr|H0Y5F5|H0Y5F5_HUMAN" 7 1599.8314 1.64 115464 11052 3 1599.834845 534.2844 Polyadenylate-binding protein 4 OS=Homo sapiens OX=9606 GN=PABPC4 PE=1 SV=1 4.36 2175.2 - 1.92E+06 - - - 2.1315 - 3.223 0.6 - 335.2 1 2 1 0.0034 13 0 0 0 8.52E+07 5.19E+07 - - - 8.4015 0.9993 221125_WJC_METTL3_EV_vs_WT_F08.11054.11054.4 0.000182 14/84 K.RSLDPADERDDVLAK.R "sp|Q8WXI9|P66B_HUMAN,tr|A0A0U1RR34|A0A0U1RR34_HUMAN,tr|A0A0U1RRM1|A0A0U1RRM1_HUMAN,tr|A0A0U1RRK3|A0A0U1RRK3_HUMAN" 4 1698.8537 2.08 115466 11054 4 1698.85111 425.7207 Transcriptional repressor p66-beta OS=Homo sapiens OX=9606 GN=GATAD2B PE=1 SV=1 4.36 2175.4 - 779029 - - - -1.511 - 2.403 0.39 - 152.3 1 2 1 -0.0026 15 0 0 0 2.09E+07 1.00E+07 - - - 2.9335 1 221125_WJC_METTL3_EV_vs_WT_F08.11060.11060.3 9.08E-09 14/60 R.HDVC[160.03]PAPSSSASHGPF.- tr|H7C0N4|H7C0N4_HUMAN 1 1651.7049 - 115471 11060 3 1651.707224 551.5756 Splicing factor 1 (Fragment) OS=Homo sapiens OX=9606 GN=SF1 PE=1 SV=1 5.97 2176.1 - 508174 - - - 1.404 - 2.778 0.629 - 185.8 1 2 0 0.0023 16 0 0 0 - - - - - 8.1737 1 221125_WJC_METTL3_EV_vs_WT_F08.11062.11062.3 1.43E-09 14/56 K.VHPEIINENGNPSYK[136.11].Y sp|O95881|TXD12_HUMAN 1 1717.8515 1.41 115472 11062 3 1717.854665 573.6244 Thioredoxin domain-containing protein 12 OS=Homo sapiens OX=9606 GN=TXNDC12 PE=1 SV=1 5.4 2176.3 - 2.07E+06 - - - 1.843 - 2.761 0.609 - 302.1 1 2 0 0.0032 15 0 0 0 6.17E+07 4.37E+07 - - - 7.9789 0.9979 221125_WJC_METTL3_EV_vs_WT_F08.11064.11064.3 8.67E-10 17/48 G.RAQVQEFC[160.03]DYGTK[136.11].E "sp|Q86U44|MTA70_HUMAN,tr|H0YFV6|H0YFV6_HUMAN" 2 1608.7446 - 115474 11064 3 1608.747756 537.2555 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 6.06 2176.4 - 1.58E+06 - - - 1.9674 - 3.122 0.585 - 507.8 1 1 0 0.0032 13 0 0 0 - - - - - 8.148 1 221125_WJC_METTL3_EV_vs_WT_F08.11067.11067.2 7.15E-06 Nov-36 K.GAEAANVTGPGGVPVQGSK[136.11].Y "sp|P67809|YBOX1_HUMAN,tr|H0Y449|H0Y449_HUMAN,tr|C9J5V9|C9J5V9_HUMAN" 3 1702.873 1.14 115477 11067 2 1702.875208 852.4438 Y-box-binding protein 1 OS=Homo sapiens OX=9606 GN=YBX1 PE=1 SV=3 6 2176.8 - 177854 - - - 1.3184 - 2.998 0.54 - 169.1 1 2 0 0.0022 19 0 0 0 3.84E+07 3.36E+07 - - - 5.7281 0.9999 221125_WJC_METTL3_EV_vs_WT_F08.11068.11068.3 4.22E-08 15/72 R.AVRPIEVTQAC[160.03]ASPGTSC[160.03]R.V "sp|Q9P0G3|KLK14_HUMAN,tr|A0A1R3UHJ7|A0A1R3UHJ7_HUMAN" 2 2058.9939 999 115478 11068 3 2059.000958 687.3386 Kallikrein-14 OS=Homo sapiens OX=9606 GN=KLK14 PE=1 SV=2 8.11 2176.9 - 103413 - - - 3.4313 - 2.905 0.578 - 216.4 1 2 0 0.0071 19 0 0 0 4.41E+06 0.00E+00 - - - 7.6022 0.9939 221125_WJC_METTL3_EV_vs_WT_F08.11072.11072.3 1.42E-07 15/72 R.SDSPVPTAPTSGGPK[136.11]PSTA.S "sp|Q86U44|MTA70_HUMAN,tr|B4E349|B4E349_HUMAN,tr|F5H6D8|F5H6D8_HUMAN,tr|B4DTN4|B4DTN4_HUMAN" 4 1760.8672 0.06 115480 11072 3 1760.87027 587.963 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 5.55 2177.4 - 931126 - - - 1.7389 - 2.579 0.487 - 273.7 1 1 0 0.0031 19 0 0 0 7.48E+06 1.17E+08 - - - 6.2963 0.998 221125_WJC_METTL3_EV_vs_WT_F08.11074.11074.2 0.000317 24-Sep K.SGDKNDDGLVEIK.V tr|A8MXP9|A8MXP9_HUMAN 1 1388.6783 1.46 115482 11074 2 1388.678702 695.3464 Matrin-3 OS=Homo sapiens OX=9606 GN=MATR3 PE=1 SV=1 4.23 2177.7 - 293026 - - - 0.2621 - 2.314 0.416 - 211 1 2 1 0.0004 13 0 0 0 5.59E+06 3.83E+06 - - - 4.2667 0.9963 221125_WJC_METTL3_EV_vs_WT_F08.11075.11075.2 0.00329 24-Nov K.SGDK[136.11]NDDGLVEIK[136.11].V tr|A8MXP9|A8MXP9_HUMAN 1 1404.7067 1.46 115483 11075 2 1404.708809 703.3606 Matrin-3 OS=Homo sapiens OX=9606 GN=MATR3 PE=1 SV=1 4.23 2177.8 - 248299 - - - 1.4743 - 2.31 0.396 - 227.8 1 2 1 0.0021 13 0 0 0 5.59E+06 3.83E+06 - - - 4.114 1 221125_WJC_METTL3_EV_vs_WT_F08.11081.11081.2 1.08E-10 17/36 K.GAEAANVTGPGGVPVQGSK.Y "sp|P67809|YBOX1_HUMAN,tr|H0Y449|H0Y449_HUMAN,tr|C9J5V9|C9J5V9_HUMAN" 3 1694.8588 1.15 115486 11081 2 1694.860142 848.4367 Y-box-binding protein 1 OS=Homo sapiens OX=9606 GN=YBX1 PE=1 SV=3 6 2178.5 - 554820 - - - 0.8136 - 3.588 0.696 - 549.7 1 2 0 0.0014 19 0 0 0 3.86E+07 3.36E+07 - - - 7.3222 0.9996 221125_WJC_METTL3_EV_vs_WT_F08.11093.11093.3 0.00957 14/64 R.RLAQQMENRPSVQAALK.L "sp|Q9Y3Y2|CHTOP_HUMAN,tr|Q5T7Y7|Q5T7Y7_HUMAN,tr|A0A087X1B7|A0A087X1B7_HUMAN,tr|X6R700|X6R700_HUMAN" 4 1939.0422 1.77 115496 11093 3 1939.04458 647.3547 Chromatin target of PRMT1 protein OS=Homo sapiens OX=9606 GN=CHTOP PE=1 SV=2 10.84 2179.9 - 1.17E+06 - - - 1.2465 - 2.314 0.307 - 175.6 1 2 0 0.0024 17 0 0 0 1.14E+07 6.41E+06 - - - 4.0816 0.9997 221125_WJC_METTL3_EV_vs_WT_F08.11094.11094.3 0.000125 18/64 R.R[166.11]LAQQMENR[166.11]PSVQAALK[136.11].L "sp|Q9Y3Y2|CHTOP_HUMAN,tr|Q5T7Y7|Q5T7Y7_HUMAN,tr|A0A087X1B7|A0A087X1B7_HUMAN,tr|X6R700|X6R700_HUMAN" 4 1967.0729 1.77 115497 11094 3 1967.07241 656.6982 Chromatin target of PRMT1 protein OS=Homo sapiens OX=9606 GN=CHTOP PE=1 SV=2 10.84 2180.1 - 446556 - - - -0.2506 - 2.831 0.287 - 253.9 1 2 0 -0.0005 17 0 0 0 1.14E+07 6.41E+06 - - - 4.3686 0.9827 221125_WJC_METTL3_EV_vs_WT_F08.11095.11095.4 0.0547 Nov-90 R.SFGTEDRPTDRPIPPR.D "sp|Q8ND56|LS14A_HUMAN,tr|I3L4Q1|I3L4Q1_HUMAN,tr|A0A140TA76|A0A140TA76_HUMAN,tr|K7EMZ9|K7EMZ9_HUMAN" 4 1839.9228 0.86 115498 11095 4 1839.926247 460.988 Protein LSM14 homolog A OS=Homo sapiens OX=9606 GN=LSM14A PE=1 SV=3 5.84 2180.2 - 346355 - - - 1.8952 - 1.888 0.191 - 73.2 1 2 0 0.0035 16 0 0 0 7.58E+06 8.79E+06 - - - 1.1114 0.9928 221125_WJC_METTL3_EV_vs_WT_F08.11097.11097.2 0.00259 24-Jun K.NLDDTIDDEKLRK.E "sp|Q13310|PABP4_HUMAN,tr|A0A7I2V5W9|A0A7I2V5W9_HUMAN,tr|H0YEU6|H0YEU6_HUMAN,tr|B1ANR0|B1ANR0_HUMAN,tr|A0A7I2V4L7|A0A7I2V4L7_HUMAN,tr|A0A7I2V598|A0A7I2V598_HUMAN,tr|H0Y5F5|H0Y5F5_HUMAN" 7 1573.7948 3.31 115500 11097 2 1573.793617 787.9047 Polyadenylate-binding protein 4 OS=Homo sapiens OX=9606 GN=PABPC4 PE=1 SV=1 4.36 2180.4 - 137915 - - - -0.7294 - 1.361 0.409 - 84.2 1 2 1 -0.0011 13 0 0 0 1.57E+06 4.75E+05 - - - 2.8526 0.9902 221125_WJC_METTL3_EV_vs_WT_F08.11102.11102.4 2.75E-08 18/78 K.PSDLHLQTGYKVER.H "sp|P24928|RPB1_HUMAN,tr|A0A6Q8PGB0|A0A6Q8PGB0_HUMAN" 2 1641.8475 1.41 115503 11102 4 1641.849396 411.4691 DNA-directed RNA polymerase II subunit RPB1 OS=Homo sapiens OX=9606 GN=POLR2A PE=1 SV=2 7.17 2181.1 - 308488 - - - 1.1731 - 3.103 0.546 - 277.5 1 1 1 0.0019 14 0 0 0 1.17E+07 8.25E+06 - - - 4.39 1 221125_WJC_METTL3_EV_vs_WT_F08.11108.11108.3 1.05E-08 13/60 K.ATAGDTHLGGEDFDNR[166.11].L "sp|P48741|HSP77_HUMAN,sp|P0DMV8|HS71A_HUMAN,sp|P34931|HS71L_HUMAN,sp|P0DMV9|HS71B_HUMAN,sp|P17066|HSP76_HUMAN,tr|Q53FA3|Q53FA3_HUMAN,tr|V9GZ37|V9GZ37_HUMAN,tr|A0A0G2JIW1|A0A0G2JIW1_HUMAN" 8 1684.7317 0.13 115508 11108 3 1684.734131 562.5845 Putative heat shock 70 kDa protein 7 OS=Homo sapiens OX=9606 GN=HSPA7 PE=5 SV=2 4.22 2181.8 - 2.93E+06 - - - 1.4661 - 2.692 0.626 - 226.3 1 2 0 0.0025 16 0 0 0 2.22E+07 1.72E+08 - - - 8.0595 0.9964 221125_WJC_METTL3_EV_vs_WT_F08.11115.11115.3 1.72E-08 13/56 F.SQPPAPPHQNTFPPR.S sp|Q96I24|FUBP3_HUMAN 1 1669.8325 10.48 115514 11115 3 1669.836047 557.6181 Far upstream element-binding protein 3 OS=Homo sapiens OX=9606 GN=FUBP3 PE=1 SV=2 9.49 2182.7 - 432359 - - - 2.1314 - 2.892 0.543 - 204.5 1 1 0 0.0036 15 0 0 0 1.30E+07 1.24E+06 - - - 7.3639 1 221125_WJC_METTL3_EV_vs_WT_F08.11120.11120.3 3.50E-05 Oct-68 R.EVGGGHGC[160.03]TSPPFPQEAR[166.11].A "sp|Q6ZN17|LN28B_HUMAN,tr|A0A1B0GVD3|A0A1B0GVD3_HUMAN" 2 1891.8511 0.96 115517 11120 3 1891.852228 631.6243 Protein lin-28 homolog B OS=Homo sapiens OX=9606 GN=LIN28B PE=1 SV=1 5.4 2183.4 - 356123 - - - 0.6147 - 1.992 0.512 - 97.4 1 2 0 0.0012 18 0 0 0 1.53E+07 1.59E+07 - - - 5.964 0.9931 221125_WJC_METTL3_EV_vs_WT_F08.11123.11123.4 1.09E-09 18/78 K.PSDLHLQTGYK[136.11]VER[166.11].H "sp|P24928|RPB1_HUMAN,tr|A0A6Q8PGB0|A0A6Q8PGB0_HUMAN" 2 1659.8699 1.53 115520 11123 4 1659.868507 415.9748 DNA-directed RNA polymerase II subunit RPB1 OS=Homo sapiens OX=9606 GN=POLR2A PE=1 SV=2 7.17 2183.7 - 386694 - - - -0.8633 - 3.383 0.593 - 239.8 1 1 1 -0.0014 14 0 0 0 1.05E+07 6.88E+06 - - - 4.8306 1 221125_WJC_METTL3_EV_vs_WT_F08.11125.11125.3 6.45E-06 15/72 K.LVNTTITPEPEPK[136.11]PQPNSR[166.11].E sp|Q86V48|LUZP1_HUMAN 1 2135.1342 0.66 115522 11125 3 2135.134845 712.7187 Leucine zipper protein 1 OS=Homo sapiens OX=9606 GN=LUZP1 PE=1 SV=2 6.14 2183.9 - 207652 - - - 0.3241 - 2.459 0.492 - 156.9 1 2 0 0.0007 19 0 0 0 2.59E+06 3.90E+06 - - - 6.2356 1 221125_WJC_METTL3_EV_vs_WT_F08.11131.11131.2 1.82E-10 16/36 R.SDSPVPTAPTSGGPKPSTA.S "sp|Q86U44|MTA70_HUMAN,tr|B4E349|B4E349_HUMAN,tr|F5H6D8|F5H6D8_HUMAN,tr|B4DTN4|B4DTN4_HUMAN" 4 1752.853 0.03 115526 11131 2 1752.855714 877.4338 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 5.55 2184.6 - 1.01E+06 - - - 1.5438 - 2.856 0.687 - 475.4 1 1 0 0.0027 19 0 0 0 4.65E+07 1.51E+09 - - - 6.6944 0.9999 221125_WJC_METTL3_EV_vs_WT_F08.11132.11132.2 8.91E-07 30-Nov R.GSYSSIVNSSSSSDPK.L sp|Q92545|TM131_HUMAN 1 1600.7217 1.39 115527 11132 2 1600.722616 801.3681 Transmembrane protein 131 OS=Homo sapiens OX=9606 GN=TMEM131 PE=1 SV=3 5.83 2184.8 - 306469 - - - 0.5972 - 2.32 0.624 - 235.9 1 2 0 0.001 16 0 0 0 1.80E+07 1.29E+07 - - - 5.7186 0.9965 221125_WJC_METTL3_EV_vs_WT_F08.11136.11136.4 0.0022 Sep-84 R.NDTK[136.11]EDVFVHQTAIK[136.11].R "sp|Q9Y2T7|YBOX2_HUMAN,sp|P67809|YBOX1_HUMAN,sp|P16989|YBOX3_HUMAN,tr|H0Y449|H0Y449_HUMAN,tr|A0A0D9SEI8|A0A0D9SEI8_HUMAN" 5 1759.9076 1.1 115529 11136 4 1759.906504 440.9842 Y-box-binding protein 2 OS=Homo sapiens OX=9606 GN=YBX2 PE=1 SV=2 5.38 2185.3 - 937552 - - - -0.6023 - 2.019 0.302 - 66.9 1 2 1 -0.0011 15 0 0 0 4.15E+08 3.76E+08 - - - 2.1057 1 221125_WJC_METTL3_EV_vs_WT_F08.11138.11138.3 2.45E-11 21/56 R.NDTKEDVFVHQTAIK.R "sp|Q9Y2T7|YBOX2_HUMAN,sp|P67809|YBOX1_HUMAN,sp|P16989|YBOX3_HUMAN,tr|H0Y449|H0Y449_HUMAN,tr|A0A0D9SEI8|A0A0D9SEI8_HUMAN" 5 1743.8792 1.2 115531 11138 3 1743.881164 582.3003 Y-box-binding protein 2 OS=Homo sapiens OX=9606 GN=YBX2 PE=1 SV=2 5.38 2185.6 - 658631 - - - 1.1469 - 4.08 0.586 - 517.5 1 2 1 0.002 15 0 0 0 3.82E+08 3.19E+08 - - - 8.7418 0.9932 221125_WJC_METTL3_EV_vs_WT_F08.11140.11140.3 0.0939 Jul-48 K.NNDKSEFLSTAPR.S sp|Q13416|ORC2_HUMAN 1 1477.7161 0.34 115533 11140 3 1477.718995 493.5793 Origin recognition complex subunit 2 OS=Homo sapiens OX=9606 GN=ORC2 PE=1 SV=2 6.07 2185.8 - 301348 - - - 1.9449 - 1.601 0.328 - 72.3 1 2 1 0.0029 13 0 0 0 4.35E+06 1.28E+07 - - - 3.4721 0.9999 221125_WJC_METTL3_EV_vs_WT_F08.11142.11142.3 2.26E-05 Sep-60 R.DGQVINETSQHHDDLE.- sp|P08670|VIME_HUMAN 1 1835.7922 - 115534 11142 3 1835.788131 612.938 Vimentin OS=Homo sapiens OX=9606 GN=VIM PE=1 SV=4 4.28 2186 - 588589 - - - -2.2159 - 2.226 0.495 - 79.6 1 2 0 -0.0041 16 0 0 0 - - - - - 6.1109 1 221125_WJC_METTL3_EV_vs_WT_F08.11146.11146.3 0.00303 16/40 R.KNHEEEMLALR.G "sp|P08779|K1C16_HUMAN,tr|K7ENW6|K7ENW6_HUMAN" 2 1368.682 729.76 115537 11146 3 1368.681343 457.2346 "Keratin, type I cytoskeletal 16 OS=Homo sapiens OX=9606 GN=KRT16 PE=1 SV=4" 5.5 2186.4 - 7.23E+06 - - - -0.4683 - 3.12 0.479 - 427 1 2 0 -0.0006 11 0 0 0 1.98E+08 2.71E+05 - - - 7.1126 0.9999 221125_WJC_METTL3_EV_vs_WT_F08.11147.11147.4 8.23E-08 17/84 R.NDTKEDVFVHQTAIK.R "sp|Q9Y2T7|YBOX2_HUMAN,sp|P67809|YBOX1_HUMAN,sp|P16989|YBOX3_HUMAN,tr|H0Y449|H0Y449_HUMAN,tr|A0A0D9SEI8|A0A0D9SEI8_HUMAN" 5 1743.8792 1.1 115538 11147 4 1743.879829 436.9771 Y-box-binding protein 2 OS=Homo sapiens OX=9606 GN=YBX2 PE=1 SV=2 5.38 2186.4 - 1.40E+06 - - - 0.3813 - 2.825 0.552 - 273.6 1 2 1 0.0007 15 0 0 0 4.15E+08 3.76E+08 - - - 4.402 1 221125_WJC_METTL3_EV_vs_WT_F08.11149.11149.4 4.52E-05 15/120 K.AATMTAAGHHAEVVVDPEDER[166.11].A "sp|Q13895|BYST_HUMAN,tr|F8WBL2|F8WBL2_HUMAN,tr|H7BY94|H7BY94_HUMAN" 3 2215.0203 0.96 115540 11149 4 2215.018735 554.7624 Bystin OS=Homo sapiens OX=9606 GN=BYSL PE=1 SV=3 4.49 2186.7 - 493638 - - - -0.7133 - 2.665 0.488 - 146.1 1 2 0 -0.0016 21 0 0 0 3.85E+07 4.00E+07 - - - 3.7972 0.9639 221125_WJC_METTL3_EV_vs_WT_F08.11150.11150.3 0.0902 Jul-36 K.WDYEK[136.11]NEWK[136.11]K[136.11].- sp|P13073|COX41_HUMAN 1 1448.7151 1.01 115541 11150 3 1448.714163 483.9123 "Cytochrome c oxidase subunit 4 isoform 1, mitochondrial OS=Homo sapiens OX=9606 GN=COX4I1 PE=1 SV=1" 6.18 2186.8 - 402259 - - - -0.6226 - 1.534 0.205 - 46.7 2 2 1 -0.0009 10 0 0 0 1.27E+07 1.26E+07 - - - 1.9356 1 221125_WJC_METTL3_EV_vs_WT_F08.11151.11151.2 2.47E-08 13/32 R.EDLNSPNPSPGGC[160.03]YDTK.V sp|Q6P4A8|PLBL1_HUMAN 1 1849.7789 999 115542 11151 2 1849.777998 925.8967 Phospholipase B-like 1 OS=Homo sapiens OX=9606 GN=PLBD1 PE=1 SV=2 4.03 2186.9 - 298050 - - - -0.4649 - 2.725 0.728 - 385 1 2 0 -0.0009 17 0 0 0 7.29E+06 0.00E+00 - - - 6.8824 0.998 221125_WJC_METTL3_EV_vs_WT_F08.11154.11154.3 3.00E-07 17/68 K.QTAISQPASGNTFSHHSM.V "sp|Q14157|UBP2L_HUMAN,tr|F8W726|F8W726_HUMAN,tr|Q5VU77|Q5VU77_HUMAN" 3 1899.8534 - 115543 11154 3 1899.8541 634.2917 Ubiquitin-associated protein 2-like OS=Homo sapiens OX=9606 GN=UBAP2L PE=1 SV=2 6.92 2187.4 - 855263 - - - 0.3895 - 2.969 0.53 - 405.8 1 1 0 0.0007 18 0 0 0 - - - - - 7.1586 0.9999 221125_WJC_METTL3_EV_vs_WT_F08.11161.11161.4 5.49E-07 15/120 K.AATMTAAGHHAEVVVDPEDER.A "sp|Q13895|BYST_HUMAN,tr|F8WBL2|F8WBL2_HUMAN,tr|H7BY94|H7BY94_HUMAN" 3 2205.012 0.96 115548 11161 4 2205.015596 552.2603 Bystin OS=Homo sapiens OX=9606 GN=BYSL PE=1 SV=3 4.49 2188.3 - 884128 - - - 1.6104 - 2.829 0.483 - 159.6 1 2 0 0.0036 21 0 0 0 3.86E+07 4.03E+07 - - - 3.7729 0.9999 221125_WJC_METTL3_EV_vs_WT_F08.11162.11162.4 2.07E-06 16/90 R.R[166.11]PLEMEQQQAYR[166.11]PEMK[136.11].T "sp|Q9BUJ2|HNRL1_HUMAN,tr|M0R0K8|M0R0K8_HUMAN,tr|M0QYZ0|M0QYZ0_HUMAN,tr|A0A0A0MRA5|A0A0A0MRA5_HUMAN,tr|M0QZV6|M0QZV6_HUMAN,tr|B7Z4B8|B7Z4B8_HUMAN,tr|M0R203|M0R203_HUMAN" 7 2061.013 1.38 115549 11162 4 2061.008591 516.2605 Heterogeneous nuclear ribonucleoprotein U-like protein 1 OS=Homo sapiens OX=9606 GN=HNRNPUL1 PE=1 SV=2 6.23 2188.4 - 466106 - - - -2.1417 - 3.202 0.497 - 221.5 1 2 0 -0.0044 16 0 0 0 7.76E+07 5.62E+07 - - - 3.9606 0.9986 221125_WJC_METTL3_EV_vs_WT_F08.11163.11163.3 0.00109 Aug-36 K.WDYEKNEWKK.- sp|P13073|COX41_HUMAN 1 1424.6725 0.99 115550 11163 3 1424.673423 475.8981 "Cytochrome c oxidase subunit 4 isoform 1, mitochondrial OS=Homo sapiens OX=9606 GN=COX4I1 PE=1 SV=1" 6.18 2188.5 - 731700 - - - 0.6724 - 1.65 0.377 - 66.6 1 2 1 0.001 10 0 0 0 1.28E+07 1.30E+07 - - - 4.2054 1 221125_WJC_METTL3_EV_vs_WT_F08.11164.11164.3 6.72E-10 19/60 R.R[166.11]PLEMEQQQAYR[166.11]PEMK[136.11].T "sp|Q9BUJ2|HNRL1_HUMAN,tr|M0R0K8|M0R0K8_HUMAN,tr|M0QYZ0|M0QYZ0_HUMAN,tr|A0A0A0MRA5|A0A0A0MRA5_HUMAN,tr|M0QZV6|M0QZV6_HUMAN,tr|B7Z4B8|B7Z4B8_HUMAN,tr|M0R203|M0R203_HUMAN" 7 2061.013 1.61 115551 11164 3 2061.011238 688.0116 Heterogeneous nuclear ribonucleoprotein U-like protein 1 OS=Homo sapiens OX=9606 GN=HNRNPUL1 PE=1 SV=2 6.23 2188.7 - 331471 - - - -0.8573 - 4.038 0.629 - 567.3 1 2 0 -0.0018 16 0 0 0 4.66E+07 2.91E+07 - - - 9.1335 0.9999 221125_WJC_METTL3_EV_vs_WT_F08.11166.11166.3 1.30E-05 Nov-72 K.LVNTTITPEPEPKPQPNSR.E sp|Q86V48|LUZP1_HUMAN 1 2117.1117 0.66 115553 11166 3 2117.11074 706.7112 Leucine zipper protein 1 OS=Homo sapiens OX=9606 GN=LUZP1 PE=1 SV=2 6.14 2188.9 - 214494 - - - -0.4454 - 2.326 0.473 - 144.8 1 2 0 -0.0009 19 0 0 0 2.59E+06 3.90E+06 - - - 5.8871 0.9999 221125_WJC_METTL3_EV_vs_WT_F08.11172.11172.3 5.86E-05 16/64 K.QVSQAQTTVQPSATLQR.S sp|O00268|TAF4_HUMAN 1 1841.9595 1.22 115557 11172 3 1841.964464 614.9938 Transcription initiation factor TFIID subunit 4 OS=Homo sapiens OX=9606 GN=TAF4 PE=1 SV=2 9.75 2189.6 - 560670 - - - 2.6738 - 2.946 0.438 - 197.8 1 2 0 0.0049 17 0 0 0 5.86E+06 4.79E+06 - - - 6.1514 1 221125_WJC_METTL3_EV_vs_WT_F08.11173.11173.4 9.18E-05 15/90 R.RPLEMEQQQAYRPEMK.T "sp|Q9BUJ2|HNRL1_HUMAN,tr|M0R0K8|M0R0K8_HUMAN,tr|M0QYZ0|M0QYZ0_HUMAN,tr|A0A0A0MRA5|A0A0A0MRA5_HUMAN,tr|M0QZV6|M0QZV6_HUMAN,tr|B7Z4B8|B7Z4B8_HUMAN,tr|M0R203|M0R203_HUMAN" 7 2032.9823 1.4 115558 11173 4 2032.985437 509.2528 Heterogeneous nuclear ribonucleoprotein U-like protein 1 OS=Homo sapiens OX=9606 GN=HNRNPUL1 PE=1 SV=2 6.23 2189.7 - 1.16E+06 - - - 1.5603 - 2.964 0.509 - 202.1 1 2 0 0.0032 16 0 0 0 7.71E+07 5.52E+07 - - - 4.0382 1 221125_WJC_METTL3_EV_vs_WT_F08.11174.11174.3 3.19E-08 24/60 R.RPLEMEQQQAYRPEMK.T "sp|Q9BUJ2|HNRL1_HUMAN,tr|M0R0K8|M0R0K8_HUMAN,tr|M0QYZ0|M0QYZ0_HUMAN,tr|A0A0A0MRA5|A0A0A0MRA5_HUMAN,tr|M0QZV6|M0QZV6_HUMAN,tr|B7Z4B8|B7Z4B8_HUMAN,tr|M0R203|M0R203_HUMAN" 7 2032.9823 1.61 115559 11174 3 2032.982321 678.668 Heterogeneous nuclear ribonucleoprotein U-like protein 1 OS=Homo sapiens OX=9606 GN=HNRNPUL1 PE=1 SV=2 6.23 2189.8 - 536584 - - - 0.0275 - 3.904 0.586 - 714.5 1 2 0 0.0001 16 0 0 0 4.66E+07 2.91E+07 - - - 8.568 1 221125_WJC_METTL3_EV_vs_WT_F08.11175.11175.3 4.82E-07 Nov-44 K.LSAMMGAVAEK[136.11]K[136.11].G "sp|Q86U44|MTA70_HUMAN,tr|F5H6D8|F5H6D8_HUMAN,tr|H0YFV6|H0YFV6_HUMAN,tr|B4DTN4|B4DTN4_HUMAN" 4 1250.6698 0.001 115560 11175 3 1250.670324 417.8972 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 8.59 2189.9 - 479868 - - - 0.447 - 2.234 0.525 - 178.8 1 2 0 0.0006 12 0 0 0 0.00E+00 7.88E+06 - - - 6.6211 1 221125_WJC_METTL3_EV_vs_WT_F08.11176.11176.3 1.81E-09 17/80 K.AATMTAAGHHAEVVVDPEDER.A "sp|Q13895|BYST_HUMAN,tr|F8WBL2|F8WBL2_HUMAN,tr|H7BY94|H7BY94_HUMAN" 3 2205.012 0.9 115561 11176 3 2205.014725 736.0113 Bystin OS=Homo sapiens OX=9606 GN=BYSL PE=1 SV=3 4.49 2190.1 - 302462 - - - 1.2154 - 3.522 0.636 - 235.6 1 2 0 0.0027 21 0 0 0 1.16E+07 1.29E+07 - - - 8.6485 0.9991 221125_WJC_METTL3_EV_vs_WT_F08.11182.11182.4 0.00514 Nov-72 K.IK[136.11]ETVDQVEELR[166.11]R[166.11].D "sp|Q14204|DYHC1_HUMAN,tr|A0A7P0T8N2|A0A7P0T8N2_HUMAN,tr|A0A7P0T9C4|A0A7P0T9C4_HUMAN,tr|A0A7P0TBJ7|A0A7P0TBJ7_HUMAN,tr|A0A7P0T9K2|A0A7P0T9K2_HUMAN,tr|A0A2R8Y706|A0A2R8Y706_HUMAN,tr|A0A7P0T916|A0A7P0T916_HUMAN,tr|A0A7P0TB75|A0A7P0TB75_HUMAN,tr|A0A7P0T8W5|A0A7P0T8W5_HUMAN,tr|A0A7P0TAF3|A0A7P0TAF3_HUMAN,tr|A0A7P0T9F1|A0A7P0T9F1_HUMAN,tr|A0A7P0TAW9|A0A7P0TAW9_HUMAN,tr|A0A7P0TA13|A0A7P0TA13_HUMAN,tr|A0A7P0T7V5|A0A7P0T7V5_HUMAN,tr|A0A7P0T9R4|A0A7P0T9R4_HUMAN,tr|A0A2R8Y5T0|A0A2R8Y5T0_HUMAN,tr|A0A2R8YFZ7|A0A2R8YFZ7_HUMAN,tr|A0A7P0T825|A0A7P0T825_HUMAN,tr|A0A2R8Y6H2|A0A2R8Y6H2_HUMAN,tr|A0A7P0TAM4|A0A7P0TAM4_HUMAN" 20 1641.9044 0.82 115565 11182 4 1641.904993 411.4834 Cytoplasmic dynein 1 heavy chain 1 OS=Homo sapiens OX=9606 GN=DYNC1H1 PE=1 SV=5 4.87 2190.9 - 636344 - - - 0.3465 - 2.128 0.373 - 127.2 1 2 1 0.0006 13 0 0 0 1.39E+07 1.70E+07 - - - 2.7524 1 221125_WJC_METTL3_EV_vs_WT_F08.11183.11183.3 8.74E-09 15/56 R.NDTK[136.11]EDVFVHQTAIK[136.11].R "sp|Q9Y2T7|YBOX2_HUMAN,sp|P67809|YBOX1_HUMAN,sp|P16989|YBOX3_HUMAN,tr|H0Y449|H0Y449_HUMAN,tr|A0A0D9SEI8|A0A0D9SEI8_HUMAN" 5 1759.9076 1.2 115566 11183 3 1759.909218 587.6431 Y-box-binding protein 2 OS=Homo sapiens OX=9606 GN=YBX2 PE=1 SV=2 5.38 2190.9 - 9.97E+06 - - - 0.9398 - 3.302 0.598 - 249.1 1 2 1 0.0017 15 0 0 0 3.82E+08 3.19E+08 - - - 8.3236 0.9984 221125_WJC_METTL3_EV_vs_WT_F08.11184.11184.4 0.0482 Aug-72 K.DLEEDHAC[160.03]IPIK[136.11]K[136.11].S sp|P13639|EF2_HUMAN 1 1582.7996 0.47 115567 11184 4 1582.798505 396.7072 Elongation factor 2 OS=Homo sapiens OX=9606 GN=EEF2 PE=1 SV=4 4.75 2190.9 - 1.66E+06 - - - -0.6874 - 1.378 0.29 - 40.8 1 2 0 -0.0011 13 0 0 0 4.14E+07 8.71E+07 - - - 1.8687 1 221125_WJC_METTL3_EV_vs_WT_F08.11185.11185.2 1.37E-11 13/32 K.QVSQAQTTVQPSATLQR.S sp|O00268|TAF4_HUMAN 1 1841.9595 2.68 115568 11185 2 1841.95682 921.987 Transcription initiation factor TFIID subunit 4 OS=Homo sapiens OX=9606 GN=TAF4 PE=1 SV=2 9.75 2191.1 - 163048 - - - -1.4761 - 2.79 0.69 - 437.4 1 2 0 -0.0027 17 0 0 0 2.40E+06 8.95E+05 - - - 6.6591 1 221125_WJC_METTL3_EV_vs_WT_F08.11188.11188.3 7.70E-08 Dec-48 K.DLEEDHAC[160.03]IPIK[136.11]K[136.11].S sp|P13639|EF2_HUMAN 1 1582.7996 0.49 115569 11188 3 1582.799923 528.6071 Elongation factor 2 OS=Homo sapiens OX=9606 GN=EEF2 PE=1 SV=4 4.75 2191.5 - 2.37E+06 - - - 0.2085 - 2.205 0.631 - 126.6 1 2 0 0.0003 13 0 0 0 4.15E+07 8.47E+07 - - - 7.7188 0.9987 221125_WJC_METTL3_EV_vs_WT_F08.11189.11189.3 0.0146 Oct-48 K.IK[136.11]ETVDQVEELR[166.11]R[166.11].D "sp|Q14204|DYHC1_HUMAN,tr|A0A7P0T8N2|A0A7P0T8N2_HUMAN,tr|A0A7P0T9C4|A0A7P0T9C4_HUMAN,tr|A0A7P0TBJ7|A0A7P0TBJ7_HUMAN,tr|A0A7P0T9K2|A0A7P0T9K2_HUMAN,tr|A0A2R8Y706|A0A2R8Y706_HUMAN,tr|A0A7P0T916|A0A7P0T916_HUMAN,tr|A0A7P0TB75|A0A7P0TB75_HUMAN,tr|A0A7P0T8W5|A0A7P0T8W5_HUMAN,tr|A0A7P0TAF3|A0A7P0TAF3_HUMAN,tr|A0A7P0T9F1|A0A7P0T9F1_HUMAN,tr|A0A7P0TAW9|A0A7P0TAW9_HUMAN,tr|A0A7P0TA13|A0A7P0TA13_HUMAN,tr|A0A7P0T7V5|A0A7P0T7V5_HUMAN,tr|A0A7P0T9R4|A0A7P0T9R4_HUMAN,tr|A0A2R8Y5T0|A0A2R8Y5T0_HUMAN,tr|A0A2R8YFZ7|A0A2R8YFZ7_HUMAN,tr|A0A7P0T825|A0A7P0T825_HUMAN,tr|A0A2R8Y6H2|A0A2R8Y6H2_HUMAN,tr|A0A7P0TAM4|A0A7P0TAM4_HUMAN" 20 1641.9044 0.96 115570 11189 3 1641.905339 548.3088 Cytoplasmic dynein 1 heavy chain 1 OS=Homo sapiens OX=9606 GN=DYNC1H1 PE=1 SV=5 4.87 2191.6 - 621566 - - - 0.5573 - 1.802 0.371 - 101.2 1 2 1 0.0009 13 0 0 0 1.93E+07 2.02E+07 - - - 4.2727 1 221125_WJC_METTL3_EV_vs_WT_F08.11190.11190.3 7.06E-11 17/68 E.EYTEETEER[166.11]EESTTGFDK[136.11].S "sp|Q9Y2W1|TR150_HUMAN,tr|A0A3B3ITZ9|A0A3B3ITZ9_HUMAN" 2 2196.9302 2.78 115571 11190 3 2196.927593 733.3173 Thyroid hormone receptor-associated protein 3 OS=Homo sapiens OX=9606 GN=THRAP3 PE=1 SV=2 3.99 2191.7 - 298989 - - - -1.1653 - 3.236 0.696 - 375.2 1 1 1 -0.0026 18 0 0 0 5.69E+07 2.05E+07 - - - 9.2232 0.995 221125_WJC_METTL3_EV_vs_WT_F08.11194.11194.3 2.00E-06 16/68 E.EYTEETEEREESTTGFDK.S "sp|Q9Y2W1|TR150_HUMAN,tr|A0A3B3ITZ9|A0A3B3ITZ9_HUMAN" 2 2178.9077 2.79 115573 11194 3 2178.905835 727.3098 Thyroid hormone receptor-associated protein 3 OS=Homo sapiens OX=9606 GN=THRAP3 PE=1 SV=2 3.99 2192.2 - 1.10E+06 - - - -0.8481 - 2.961 0.626 - 312.8 1 1 1 -0.0018 18 0 0 0 5.71E+07 2.05E+07 - - - 8.2218 1 221125_WJC_METTL3_EV_vs_WT_F08.11195.11195.3 1.12E-11 22/80 K.AATMTAAGHHAEVVVDPEDER[166.11].A "sp|Q13895|BYST_HUMAN,tr|F8WBL2|F8WBL2_HUMAN,tr|H7BY94|H7BY94_HUMAN" 3 2215.0203 0.9 115574 11195 3 2215.019618 739.3474 Bystin OS=Homo sapiens OX=9606 GN=BYSL PE=1 SV=3 4.49 2192.3 - 631485 - - - -0.3147 - 4.287 0.701 - 363.9 1 2 0 -0.0007 21 0 0 0 1.16E+07 1.29E+07 - - - 9.845 0.9753 221125_WJC_METTL3_EV_vs_WT_F08.11196.11196.4 0.718 Sep-72 K.DLEEDHAC[160.03]IPIKK.S sp|P13639|EF2_HUMAN 1 1566.7712 0.47 115575 11196 4 1566.770373 392.7001 Elongation factor 2 OS=Homo sapiens OX=9606 GN=EEF2 PE=1 SV=4 4.75 2192.4 - 1.58E+06 - - - -0.5234 - 1.162 0.181 - 49.9 1 2 0 -0.0008 13 0 0 0 4.13E+07 8.71E+07 - - - 0.8569 1 221125_WJC_METTL3_EV_vs_WT_F08.11197.11197.3 0.000117 14/68 R.EVGGGHGC[160.03]TSPPFPQEAR.A "sp|Q6ZN17|LN28B_HUMAN,tr|A0A1B0GVD3|A0A1B0GVD3_HUMAN" 2 1881.8428 0.96 115576 11197 3 1881.841499 628.2882 Protein lin-28 homolog B OS=Homo sapiens OX=9606 GN=LIN28B PE=1 SV=1 5.4 2192.5 - 498678 - - - -0.6887 - 2.472 0.522 - 226.6 1 2 0 -0.0013 18 0 0 0 1.52E+07 1.59E+07 - - - 6.613 1 221125_WJC_METTL3_EV_vs_WT_F08.11198.11198.2 3.39E-11 17/28 R.NDTKEDVFVHQTAIK.R "sp|Q9Y2T7|YBOX2_HUMAN,sp|P67809|YBOX1_HUMAN,sp|P16989|YBOX3_HUMAN,tr|H0Y449|H0Y449_HUMAN,tr|A0A0D9SEI8|A0A0D9SEI8_HUMAN" 5 1743.8792 999 115577 11198 2 1743.880438 872.9469 Y-box-binding protein 2 OS=Homo sapiens OX=9606 GN=YBX2 PE=1 SV=2 5.38 2192.6 - 381444 - - - 0.7306 - 3.592 0.687 - 1113.7 1 2 1 0.0013 15 0 0 0 8.15E+06 0.00E+00 - - - 7.2585 1 221125_WJC_METTL3_EV_vs_WT_F08.11199.11199.4 1.80E-07 14/84 R.VYVVGTAHFSDDSKR.D "sp|Q9H4I3|TRABD_HUMAN,tr|J3KPT4|J3KPT4_HUMAN" 2 1679.8267 0.67 115578 11199 4 1679.825058 420.964 TraB domain-containing protein OS=Homo sapiens OX=9606 GN=TRABD PE=1 SV=1 6.72 2192.8 - 327172 - - - -0.9977 - 2.492 0.579 - 128.2 1 2 0 -0.0017 15 0 0 0 3.80E+06 5.64E+06 - - - 4.5919 0.8238 221125_WJC_METTL3_EV_vs_WT_F08.11200.11200.3 1.15 Aug-84 K.STYDGLHVITGTTENSPADRC[160.03]K[136.11].K "sp|Q8WXI2|CNKR2_HUMAN,tr|A0A2R8Y5R2|A0A2R8Y5R2_HUMAN,tr|A0A2R8YE27|A0A2R8YE27_HUMAN,tr|A0A2R8YED7|A0A2R8YED7_HUMAN,tr|A0A2R8YFM1|A0A2R8YFM1_HUMAN,tr|A0A2R8YGJ7|A0A2R8YGJ7_HUMAN,tr|A0A2R8Y7K8|A0A2R8Y7K8_HUMAN,tr|A0A2R8Y7A1|A0A2R8Y7A1_HUMAN,tr|A0A2R8YDB6|A0A2R8YDB6_HUMAN,tr|A0A2R8Y622|A0A2R8Y622_HUMAN,tr|A0A2U3TZH5|A0A2U3TZH5_HUMAN,tr|A0A2R8Y700|A0A2R8Y700_HUMAN,tr|A0A2R8Y5S6|A0A2R8Y5S6_HUMAN" 13 2429.1373 - 115579 11200 3 2429.133828 810.7197 Connector enhancer of kinase suppressor of ras 2 OS=Homo sapiens OX=9606 GN=CNKSR2 PE=1 SV=1 5.36 2192.9 - 314716 - - - -1.41 - 1.367 0.158 - 53.7 1 2 1 -0.0034 22 0 0 0 - - - - - 1.0418 0.9998 221125_WJC_METTL3_EV_vs_WT_F08.11204.11204.2 3.01E-06 26-Sep K.K[136.11]GPGEVAGTVTGQK[136.11].R "sp|Q86U44|MTA70_HUMAN,tr|F5H6D8|F5H6D8_HUMAN,tr|H0YFV6|H0YFV6_HUMAN,tr|B4DTN4|B4DTN4_HUMAN" 4 1343.738 0.001 115583 11204 2 1343.736378 672.8763 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 8.59 2193.4 - 134155 - - - -1.1915 - 2.146 0.485 - 208.4 1 2 0 -0.0016 14 0 0 0 0.00E+00 8.07E+06 - - - 4.5389 1 221125_WJC_METTL3_EV_vs_WT_F08.11208.11208.3 4.94E-09 Dec-48 K.DLEEDHAC[160.03]IPIKK.S sp|P13639|EF2_HUMAN 1 1566.7712 0.49 115585 11208 3 1566.77195 523.2643 Elongation factor 2 OS=Homo sapiens OX=9606 GN=EEF2 PE=1 SV=4 4.75 2193.9 - 2.32E+06 - - - 0.4832 - 2.504 0.597 - 126.3 1 2 0 0.0008 13 0 0 0 4.15E+07 8.46E+07 - - - 7.6844 0.9989 221125_WJC_METTL3_EV_vs_WT_F08.11210.11210.3 0.0102 15/48 K.IKETVDQVEELRR.D "sp|Q14204|DYHC1_HUMAN,tr|A0A7P0T8N2|A0A7P0T8N2_HUMAN,tr|A0A7P0T9C4|A0A7P0T9C4_HUMAN,tr|A0A7P0TBJ7|A0A7P0TBJ7_HUMAN,tr|A0A7P0T9K2|A0A7P0T9K2_HUMAN,tr|A0A2R8Y706|A0A2R8Y706_HUMAN,tr|A0A7P0T916|A0A7P0T916_HUMAN,tr|A0A7P0TB75|A0A7P0TB75_HUMAN,tr|A0A7P0T8W5|A0A7P0T8W5_HUMAN,tr|A0A7P0TAF3|A0A7P0TAF3_HUMAN,tr|A0A7P0T9F1|A0A7P0T9F1_HUMAN,tr|A0A7P0TAW9|A0A7P0TAW9_HUMAN,tr|A0A7P0TA13|A0A7P0TA13_HUMAN,tr|A0A7P0T7V5|A0A7P0T7V5_HUMAN,tr|A0A7P0T9R4|A0A7P0T9R4_HUMAN,tr|A0A2R8Y5T0|A0A2R8Y5T0_HUMAN,tr|A0A2R8YFZ7|A0A2R8YFZ7_HUMAN,tr|A0A7P0T825|A0A7P0T825_HUMAN,tr|A0A2R8Y6H2|A0A2R8Y6H2_HUMAN,tr|A0A7P0TAM4|A0A7P0TAM4_HUMAN" 20 1613.8737 0.96 115587 11210 3 1613.874915 538.9652 Cytoplasmic dynein 1 heavy chain 1 OS=Homo sapiens OX=9606 GN=DYNC1H1 PE=1 SV=5 4.87 2194 - 1.54E+06 - - - 0.7628 - 2.143 0.338 - 203.9 1 2 1 0.0012 13 0 0 0 1.93E+07 2.02E+07 - - - 4.3746 0.9998 221125_WJC_METTL3_EV_vs_WT_F08.11211.11211.3 2.82E-05 Nov-52 R.TK[136.11]NETDEDGWTTVR[166.11].R sp|Q14152|EIF3A_HUMAN 1 1668.771 2.12 115588 11211 3 1668.771521 557.2643 Eukaryotic translation initiation factor 3 subunit A OS=Homo sapiens OX=9606 GN=EIF3A PE=1 SV=1 4.32 2194.1 - 864660 - - - 0.3044 - 2.129 0.512 - 164.9 1 2 1 0.0005 14 0 0 0 6.63E+07 3.12E+07 - - - 6.2563 0.9999 221125_WJC_METTL3_EV_vs_WT_F08.11212.11212.3 0.000787 13/60 K.LPSRPGAQGVEPQNLR.T "sp|Q8WXI9|P66B_HUMAN,tr|A0A0U1RRM1|A0A0U1RRM1_HUMAN" 2 1717.9224 2.52 115589 11212 3 1717.924172 573.6481 Transcriptional repressor p66-beta OS=Homo sapiens OX=9606 GN=GATAD2B PE=1 SV=1 9.6 2194.2 - 834972 - - - 1.0513 - 2.499 0.41 - 165.2 1 2 0 0.0018 16 0 0 0 1.68E+07 6.66E+06 - - - 5.4606 0.9999 221125_WJC_METTL3_EV_vs_WT_F08.11214.11214.3 7.58E-05 Aug-48 R.K[136.11]VLK[136.11]PIQLTDPGK[136.11].L "sp|Q9Y2P8|RCL1_HUMAN,tr|Q5VZU3|Q5VZU3_HUMAN" 2 1459.9189 1.16 115591 11214 3 1459.919887 487.6469 RNA 3'-terminal phosphate cyclase-like protein OS=Homo sapiens OX=9606 GN=RCL1 PE=1 SV=3 9.7 2194.4 - 287171 - - - 0.7103 - 1.739 0.487 - 73.4 1 2 0 0.001 13 0 0 0 5.37E+06 4.65E+06 - - - 5.4695 0.9998 221125_WJC_METTL3_EV_vs_WT_F08.11215.11215.3 0.000881 Nov-68 R.APEQR[166.11]PAPNAAPVDPTLR[166.11].T "sp|Q6P1J9|CDC73_HUMAN,tr|A0A2R8YHB3|A0A2R8YHB3_HUMAN,tr|A0A3B3IRP5|A0A3B3IRP5_HUMAN" 3 1919.0128 2.6 115592 11215 3 1919.012483 640.6782 Parafibromin OS=Homo sapiens OX=9606 GN=CDC73 PE=1 SV=1 6.12 2194.5 - 171081 - - - -0.1647 - 2.165 0.354 - 99.8 1 2 0 -0.0003 18 0 0 0 5.63E+06 2.16E+06 - - - 4.4101 0.9988 221125_WJC_METTL3_EV_vs_WT_F08.11219.11219.4 0.000828 17/72 K.IKETVDQVEELRR.D "sp|Q14204|DYHC1_HUMAN,tr|A0A7P0T8N2|A0A7P0T8N2_HUMAN,tr|A0A7P0T9C4|A0A7P0T9C4_HUMAN,tr|A0A7P0TBJ7|A0A7P0TBJ7_HUMAN,tr|A0A7P0T9K2|A0A7P0T9K2_HUMAN,tr|A0A2R8Y706|A0A2R8Y706_HUMAN,tr|A0A7P0T916|A0A7P0T916_HUMAN,tr|A0A7P0TB75|A0A7P0TB75_HUMAN,tr|A0A7P0T8W5|A0A7P0T8W5_HUMAN,tr|A0A7P0TAF3|A0A7P0TAF3_HUMAN,tr|A0A7P0T9F1|A0A7P0T9F1_HUMAN,tr|A0A7P0TAW9|A0A7P0TAW9_HUMAN,tr|A0A7P0TA13|A0A7P0TA13_HUMAN,tr|A0A7P0T7V5|A0A7P0T7V5_HUMAN,tr|A0A7P0T9R4|A0A7P0T9R4_HUMAN,tr|A0A2R8Y5T0|A0A2R8Y5T0_HUMAN,tr|A0A2R8YFZ7|A0A2R8YFZ7_HUMAN,tr|A0A7P0T825|A0A7P0T825_HUMAN,tr|A0A2R8Y6H2|A0A2R8Y6H2_HUMAN,tr|A0A7P0TAM4|A0A7P0TAM4_HUMAN" 20 1613.8737 0.82 115594 11219 4 1613.874889 404.4757 Cytoplasmic dynein 1 heavy chain 1 OS=Homo sapiens OX=9606 GN=DYNC1H1 PE=1 SV=5 4.87 2195 - 951781 - - - 0.7467 - 2.452 0.35 - 309.7 1 2 1 0.0012 13 0 0 0 1.39E+07 1.70E+07 - - - 2.6046 0.9984 221125_WJC_METTL3_EV_vs_WT_F08.11222.11222.3 0.000922 Oct-44 K.HFVGMLPEKDC[160.03]R.Y "sp|P60981|DEST_HUMAN,tr|F6RFD5|F6RFD5_HUMAN" 2 1487.7013 1.53 115597 11222 3 1487.703788 496.9077 Destrin OS=Homo sapiens OX=9606 GN=DSTN PE=1 SV=3 6.74 2195.4 - 282457 - - - 1.6455 - 1.907 0.373 - 137.4 1 2 1 0.0024 12 0 0 0 5.74E+06 3.76E+06 - - - 4.4872 0.9823 221125_WJC_METTL3_EV_vs_WT_F08.11228.11228.3 8.64E-08 16/52 N.DTKEDVFVHQTAIK.R "sp|Q9Y2T7|YBOX2_HUMAN,sp|P67809|YBOX1_HUMAN,sp|P16989|YBOX3_HUMAN,tr|H0Y449|H0Y449_HUMAN,tr|A0A0D9SEI8|A0A0D9SEI8_HUMAN" 5 1629.8362 0.81 115601 11228 3 1629.839571 544.286 Y-box-binding protein 2 OS=Homo sapiens OX=9606 GN=YBX2 PE=1 SV=2 5.38 2196.1 - 353204 - - - 2.0462 - 2.9 0.52 - 215.5 1 1 1 0.0033 14 0 0 0 6.19E+06 7.61E+06 - - - 7.1661 1 221125_WJC_METTL3_EV_vs_WT_F08.11237.11237.3 9.43E-05 Dec-60 K.STAGDTHLGGEDFDNR[166.11].M "sp|P54652|HSP72_HUMAN,sp|P11142|HSP7C_HUMAN,tr|E9PKE3|E9PKE3_HUMAN,tr|E9PN89|E9PN89_HUMAN" 4 1700.7266 0.15 115607 11237 3 1700.728118 567.9161 Heat shock-related 70 kDa protein 2 OS=Homo sapiens OX=9606 GN=HSPA2 PE=1 SV=1 4.22 2197.1 - 862146 - - - 0.9067 - 2.648 0.461 - 178.1 1 2 0 0.0015 16 0 0 0 5.18E+06 3.50E+07 - - - 6.1779 0.9999 221125_WJC_METTL3_EV_vs_WT_F08.11239.11239.3 5.99E-06 Dec-52 R.TKNETDEDGWTTVR.R sp|Q14152|EIF3A_HUMAN 1 1650.7485 2.1 115608 11239 3 1650.750764 551.2568 Eukaryotic translation initiation factor 3 subunit A OS=Homo sapiens OX=9606 GN=EIF3A PE=1 SV=1 4.32 2197.3 - 2.24E+06 - - - 1.3455 - 2.553 0.587 - 186.7 1 2 1 0.0022 14 0 0 0 6.60E+07 3.15E+07 - - - 7.5747 1 221125_WJC_METTL3_EV_vs_WT_F08.11242.11242.2 1.81E-07 16/34 K.GFDTSSSSSNSAASSSFK.F sp|P49790|NU153_HUMAN 1 1752.7439 1.45 115611 11242 2 1752.747695 877.3792 Nuclear pore complex protein Nup153 OS=Homo sapiens OX=9606 GN=NUP153 PE=1 SV=2 5.84 2197.7 - 380011 - - - 2.1926 - 3.671 0.682 - 924.9 1 2 0 0.0038 18 0 0 0 6.06E+07 4.17E+07 - - - 7.2743 0.9996 221125_WJC_METTL3_EV_vs_WT_F08.11249.11249.3 3.43E-07 14/76 R.GRPAGGNGSGLC[160.03]GGGVLGAR.S sp|Q5JSZ5|PRC2B_HUMAN 1 1768.8751 1.34 115616 11249 3 1768.884278 590.6323 Protein PRRC2B OS=Homo sapiens OX=9606 GN=PRRC2B PE=1 SV=2 10.35 2198.6 - 480207 - - - 5.1897 - 2.953 0.516 - 183.2 1 2 0 0.0092 20 0 0 0 2.01E+07 1.50E+07 - - - 6.9173 0.9988 221125_WJC_METTL3_EV_vs_WT_F08.11250.11250.4 0.00301 Sep-96 K.FVQLKPGEKPVPVDQTK.K "sp|O75586|MED6_HUMAN,tr|G3V4A5|G3V4A5_HUMAN,tr|A0A087WYL7|A0A087WYL7_HUMAN" 3 1909.0673 1.35 115617 11250 4 1909.071381 478.2741 Mediator of RNA polymerase II transcription subunit 6 OS=Homo sapiens OX=9606 GN=MED6 PE=1 SV=2 8.5 2198.7 - 404734 - - - 2.1382 - 2.102 0.313 - 55.7 1 2 0 0.0041 17 0 0 0 9.47E+06 7.01E+06 - - - 2.2072 0.9998 221125_WJC_METTL3_EV_vs_WT_F08.11252.11252.3 0.00095 17/48 R.K[136.11]AAALEAMK[136.11]DYTK[136.11].A "sp|P31948|STIP1_HUMAN,tr|H0YGI8|H0YGI8_HUMAN" 2 1462.7916 1.26 115619 11252 3 1462.790453 488.6045 Stress-induced-phosphoprotein 1 OS=Homo sapiens OX=9606 GN=STIP1 PE=1 SV=1 8.43 2199 - 280170 - - - -0.7848 - 2.897 0.437 - 342.1 1 2 1 -0.0011 13 0 0 0 1.18E+07 9.39E+06 - - - 6.2957 0.9998 221125_WJC_METTL3_EV_vs_WT_F08.11253.11253.3 2.89E-05 Nov-64 K.FVQLKPGEKPVPVDQTK.K "sp|O75586|MED6_HUMAN,tr|G3V4A5|G3V4A5_HUMAN,tr|A0A087WYL7|A0A087WYL7_HUMAN" 3 1909.0673 1.11 115620 11253 3 1909.073068 637.363 Mediator of RNA polymerase II transcription subunit 6 OS=Homo sapiens OX=9606 GN=MED6 PE=1 SV=2 8.5 2199.1 - 228402 - - - 3.0219 - 1.978 0.488 - 128 1 2 0 0.0058 17 0 0 0 2.93E+06 2.64E+06 - - - 5.7023 0.9973 221125_WJC_METTL3_EV_vs_WT_F08.11256.11256.2 3.40E-05 26-Jul R.TKNETDEDGWTTVR.R sp|Q14152|EIF3A_HUMAN 1 1650.7485 0.79 115623 11256 2 1650.750977 826.3815 Eukaryotic translation initiation factor 3 subunit A OS=Homo sapiens OX=9606 GN=EIF3A PE=1 SV=1 4.32 2199.5 - 104584 - - - 1.4745 - 1.863 0.538 - 97.9 1 2 1 0.0024 14 0 0 0 9.15E+05 1.15E+06 - - - 4.5753 1 221125_WJC_METTL3_EV_vs_WT_F08.11260.11260.2 2.78E-14 17/34 K.GFDTSSSSSNSAASSSFK[136.11].F sp|P49790|NU153_HUMAN 1 1760.7581 1.45 115625 11260 2 1760.759067 881.3863 Nuclear pore complex protein Nup153 OS=Homo sapiens OX=9606 GN=NUP153 PE=1 SV=2 5.84 2200 - 1.30E+06 - - - 0.5765 - 3.717 0.636 - 988.5 1 2 0 0.001 18 0 0 0 6.06E+07 4.17E+07 - - - 6.966 0.7932 221125_WJC_METTL3_EV_vs_WT_F08.11262.11262.3 0.00103 Sep-56 K.R[166.11]R[166.11]AEQDSTTVAAFAS.S "sp|Q86U44|MTA70_HUMAN,tr|F5H6D8|F5H6D8_HUMAN,tr|H0YFV6|H0YFV6_HUMAN,tr|B4DTN4|B4DTN4_HUMAN" 4 1628.8021 0.03 115627 11262 3 1628.801963 543.9413 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 6.07 2200.2 - 3.32E+06 - - - -0.1074 - 1.697 0.345 - 93 1 1 1 -0.0002 15 0 0 0 2.13E+07 6.24E+08 - - - 3.7664 0.9995 221125_WJC_METTL3_EV_vs_WT_F08.11264.11264.2 0.00173 12-Jun K.DNNLLGR[166.11].F "sp|P0DMV8|HS71A_HUMAN,sp|P34931|HS71L_HUMAN,sp|P0DMV9|HS71B_HUMAN,sp|P17066|HSP76_HUMAN,tr|Q53FA3|Q53FA3_HUMAN,tr|V9GZ37|V9GZ37_HUMAN,tr|A0A0G2JIW1|A0A0G2JIW1_HUMAN" 7 810.4223 0.36 115629 11264 2 810.422155 406.2184 Heat shock 70 kDa protein 1A OS=Homo sapiens OX=9606 GN=HSPA1A PE=1 SV=1 5.84 2200.4 - 467031 - - - -0.2233 - 1.475 0.375 - 222.2 1 2 0 -0.0002 7 0 0 0 2.84E+06 7.87E+06 - - - 3.0422 0.9987 221125_WJC_METTL3_EV_vs_WT_F08.11267.11267.2 0.0922 14-Jul K.DIDIHEVR.L "sp|Q00839|HNRPU_HUMAN,tr|A0A1W2PQL0|A0A1W2PQL0_HUMAN,tr|A0A1W2PPL4|A0A1W2PPL4_HUMAN,tr|A0A1W2PQ74|A0A1W2PQ74_HUMAN,tr|Q5RI18|Q5RI18_HUMAN,tr|A0A1W2PP35|A0A1W2PP35_HUMAN,tr|A0A1W2PPS1|A0A1W2PPS1_HUMAN,tr|A0A1W2PRZ7|A0A1W2PRZ7_HUMAN,tr|A0A1W2PPH7|A0A1W2PPH7_HUMAN,tr|A0A1W2PP34|A0A1W2PP34_HUMAN,tr|A0A1X7SBS1|A0A1X7SBS1_HUMAN" 11 995.5036 1.5 115632 11267 2 995.503899 498.7591 Heterogeneous nuclear ribonucleoprotein U OS=Homo sapiens OX=9606 GN=HNRNPU PE=1 SV=6 4.54 2200.8 - 203067 - - - 0.2913 - 1.616 0.229 - 156 1 2 0 0.0003 8 0 0 0 3.54E+06 2.37E+06 - - - 2.1798 0.9996 221125_WJC_METTL3_EV_vs_WT_F08.11272.11272.3 0.042 15/56 R.GPHPSQGPIPFQQQK.T sp|Q9C0J8|WDR33_HUMAN 1 1644.8372 2 115635 11272 3 1644.841822 549.2864 pre-mRNA 3' end processing protein WDR33 OS=Homo sapiens OX=9606 GN=WDR33 PE=1 SV=2 8.76 2201.5 - 2.38E+06 - - - 2.7863 - 2.82 0.346 - 301.6 1 2 0 0.0046 15 0 0 0 6.38E+07 3.19E+07 - - - 5.1015 1 221125_WJC_METTL3_EV_vs_WT_F08.11273.11273.3 2.59E-08 13/68 K.GFDTSSSSSNSAASSSFK.F sp|P49790|NU153_HUMAN 1 1752.7439 1.69 115636 11273 3 1752.745479 585.2552 Nuclear pore complex protein Nup153 OS=Homo sapiens OX=9606 GN=NUP153 PE=1 SV=2 5.84 2201.6 - 706490 - - - 0.9283 - 2.542 0.598 - 153.8 1 2 0 0.0016 18 0 0 0 1.10E+07 6.55E+06 - - - 7.5298 0.9992 221125_WJC_METTL3_EV_vs_WT_F08.11277.11277.4 5.66E-05 Dec-78 R.LEEELANLK[136.11]DESK[136.11]K[136.11].E "sp|Q14789|GOGB1_HUMAN,tr|E7EU81|E7EU81_HUMAN,tr|H0Y867|H0Y867_HUMAN" 3 1668.8996 1.01 115640 11277 4 1668.899212 418.2322 Golgin subfamily B member 1 OS=Homo sapiens OX=9606 GN=GOLGB1 PE=1 SV=2 4.59 2202.1 - 247847 - - - -0.2511 - 1.974 0.381 - 105.4 1 2 1 -0.0004 14 0 0 0 4.18E+06 4.13E+06 - - - 2.7896 0.8581 221125_WJC_METTL3_EV_vs_WT_F08.11278.11278.4 0.839 Sep-72 K.NISHVHTMDFSPR[166.11].S sp|Q9Y5J1|UTP18_HUMAN 1 1549.7335 1.09 115641 11278 4 1549.735247 388.4407 U3 small nucleolar RNA-associated protein 18 homolog OS=Homo sapiens OX=9606 GN=UTP18 PE=1 SV=3 6.92 2202.2 - 203316 - - - 1.117 - 1.339 0.107 - 49.1 1 2 0 0.0017 13 0 0 0 3.34E+06 3.07E+06 - - - 0.2651 1 221125_WJC_METTL3_EV_vs_WT_F08.11281.11281.3 6.65E-06 14/56 R.GPHPSQGPIPFQQQK[136.11].T sp|Q9C0J8|WDR33_HUMAN 1 1652.8514 2 115642 11281 3 1652.853838 551.9578 pre-mRNA 3' end processing protein WDR33 OS=Homo sapiens OX=9606 GN=WDR33 PE=1 SV=2 8.76 2202.6 - 1.66E+06 - - - 1.4514 - 2.699 0.464 - 256.1 1 2 0 0.0024 15 0 0 0 6.38E+07 3.19E+07 - - - 6.3033 0.9985 221125_WJC_METTL3_EV_vs_WT_F08.11282.11282.3 0.052 14/56 K.NSSTIIQNPVETPK[136.11]K[136.11].D sp|P38432|COIL_HUMAN 1 1670.9174 0.82 115643 11282 3 1670.916591 557.9797 Coilin OS=Homo sapiens OX=9606 GN=COIL PE=1 SV=1 8.59 2202.7 - 584989 - - - -0.4842 - 2.194 0.218 - 211.9 1 2 0 -0.0008 15 0 0 0 8.91E+06 1.08E+07 - - - 3.0205 0.9997 221125_WJC_METTL3_EV_vs_WT_F08.11283.11283.4 0.00219 13/78 K.VEYSEEELKTHISK.G "sp|P12956|XRCC6_HUMAN,tr|B1AHC9|B1AHC9_HUMAN" 2 1690.8414 1.11 115644 11283 4 1690.843302 423.7176 X-ray repair cross-complementing protein 6 OS=Homo sapiens OX=9606 GN=XRCC6 PE=1 SV=2 4.91 2202.8 - 1.06E+06 - - - 1.1361 - 2.632 0.446 - 94.3 1 2 1 0.0019 14 0 0 0 1.03E+08 9.28E+07 - - - 3.4597 1 221125_WJC_METTL3_EV_vs_WT_F08.11285.11285.3 1.93E-09 Dec-68 K.GFDTSSSSSNSAASSSFK[136.11].F sp|P49790|NU153_HUMAN 1 1760.7581 1.69 115646 11285 3 1760.761429 587.9266 Nuclear pore complex protein Nup153 OS=Homo sapiens OX=9606 GN=NUP153 PE=1 SV=2 5.84 2203.1 - 592371 - - - 1.9179 - 2.687 0.626 - 142.5 1 2 0 0.0034 18 0 0 0 1.10E+07 6.55E+06 - - - 7.9796 1 221125_WJC_METTL3_EV_vs_WT_F08.11286.11286.3 4.61E-08 14/44 R.HSLHEEENNIFK.R sp|Q96CB9|NSUN4_HUMAN 1 1495.7056 0.94 115647 11286 3 1495.707803 499.5758 5-methylcytosine rRNA methyltransferase NSUN4 OS=Homo sapiens OX=9606 GN=NSUN4 PE=1 SV=2 5.33 2203.2 - 345025 - - - 1.5023 - 3.047 0.621 - 231.6 1 2 0 0.0022 12 0 0 0 6.90E+06 7.38E+06 - - - 8.5512 0.9999 221125_WJC_METTL3_EV_vs_WT_F08.11287.11287.3 1.42E-06 15/48 R.HEVLLISAEQDKR.A "sp|Q00341|VIGLN_HUMAN,tr|A0A024R4E5|A0A024R4E5_HUMAN,tr|C9JIZ1|C9JIZ1_HUMAN,tr|H7C0A4|H7C0A4_HUMAN,tr|H0Y394|H0Y394_HUMAN" 5 1536.826 1.36 115648 11287 3 1536.829194 513.2826 Vigilin OS=Homo sapiens OX=9606 GN=HDLBP PE=1 SV=2 5.45 2203.3 - 305212 - - - 2.0744 - 2.878 0.378 - 337.4 1 2 0 0.0032 13 0 0 0 6.12E+06 4.51E+06 - - - 5.6195 1 221125_WJC_METTL3_EV_vs_WT_F08.11289.11289.2 7.09E-07 30-Dec K.SSSTALTTNVTEQTEK[136.11].D sp|Q8WYP5|ELYS_HUMAN 1 1703.8305 1.17 115650 11289 2 1703.830252 852.9225 Protein ELYS OS=Homo sapiens OX=9606 GN=AHCTF1 PE=1 SV=3 4.53 2203.6 - 234274 - - - -0.1391 - 2.562 0.636 - 462.2 1 2 0 -0.0002 16 0 0 0 2.77E+06 2.37E+06 - - - 6.0514 0.9997 221125_WJC_METTL3_EV_vs_WT_F08.11293.11293.4 0.000187 Nov-78 K.VEYSEEELK[136.11]THISK[136.11].G "sp|P12956|XRCC6_HUMAN,tr|B1AHC9|B1AHC9_HUMAN" 2 1706.8698 1.11 115652 11293 4 1706.870266 427.7247 X-ray repair cross-complementing protein 6 OS=Homo sapiens OX=9606 GN=XRCC6 PE=1 SV=2 4.91 2204.1 - 2.93E+06 - - - 0.2841 - 2.388 0.442 - 66.9 1 2 1 0.0005 14 0 0 0 1.03E+08 9.28E+07 - - - 3.3898 0.9999 221125_WJC_METTL3_EV_vs_WT_F08.11294.11294.3 8.27E-09 13/52 K.VEYSEEELK[136.11]THISK[136.11].G "sp|P12956|XRCC6_HUMAN,tr|B1AHC9|B1AHC9_HUMAN" 2 1706.8698 1.09 115653 11294 3 1706.870115 569.9639 X-ray repair cross-complementing protein 6 OS=Homo sapiens OX=9606 GN=XRCC6 PE=1 SV=2 4.91 2204.2 - 1.76E+06 - - - 0.1957 - 2.991 0.561 - 207.6 1 2 1 0.0003 14 0 0 0 6.63E+07 6.05E+07 - - - 7.7061 0.9999 221125_WJC_METTL3_EV_vs_WT_F08.11295.11295.3 2.56E-09 14/52 K.VEYSEEELKTHISK.G "sp|P12956|XRCC6_HUMAN,tr|B1AHC9|B1AHC9_HUMAN" 2 1690.8414 1.09 115654 11295 3 1690.842383 564.6211 X-ray repair cross-complementing protein 6 OS=Homo sapiens OX=9606 GN=XRCC6 PE=1 SV=2 4.91 2204.3 - 1.42E+06 - - - 0.5926 - 3.033 0.544 - 252 1 2 1 0.001 14 0 0 0 6.63E+07 6.05E+07 - - - 7.5535 0.9781 221125_WJC_METTL3_EV_vs_WT_F08.11299.11299.4 0.0801 Sep-96 K.IINEVSK[136.11]PLAHHIPVEK[136.11].L sp|P55145|MANF_HUMAN 1 1939.1226 0.62 115658 11299 4 1939.121465 485.7879 Mesencephalic astrocyte-derived neurotrophic factor OS=Homo sapiens OX=9606 GN=MANF PE=1 SV=3 6.92 2204.7 - 452095 - - - -0.576 - 1.779 0.169 - 39.6 1 2 0 -0.0011 17 0 0 0 5.96E+06 9.54E+06 - - - 0.8967 1 221125_WJC_METTL3_EV_vs_WT_F08.11301.11301.3 7.57E-08 14/48 K.K[136.11]PLPDHVSIVEPK[136.11].D "sp|P23396|RS3_HUMAN,tr|H0YEU2|H0YEU2_HUMAN,tr|E9PSF4|E9PSF4_HUMAN,tr|E9PL09|E9PL09_HUMAN,tr|E9PPU1|E9PPU1_HUMAN" 5 1473.8526 0.61 115660 11301 3 1473.855361 492.2915 40S ribosomal protein S3 OS=Homo sapiens OX=9606 GN=RPS3 PE=1 SV=2 6.75 2205 - 237391 - - - 1.8631 - 2.754 0.524 - 250.6 1 2 0 0.0027 13 0 0 0 1.10E+07 1.82E+07 - - - 7.128 0.9998 221125_WJC_METTL3_EV_vs_WT_F08.11314.11314.4 0.00069 Dec-78 K.AVQLK[136.11]PR[166.11]PPQGLVR[166.11].V "sp|Q13724|MOGS_HUMAN,tr|A0A3B3IRK6|A0A3B3IRK6_HUMAN,tr|A0A3B3IRW2|A0A3B3IRW2_HUMAN" 3 1585.9775 0.93 115671 11314 4 1585.979844 397.5016 Mannosyl-oligosaccharide glucosidase OS=Homo sapiens OX=9606 GN=MOGS PE=1 SV=5 12.01 2206.4 - 174152 - - - 1.4969 - 2.08 0.391 - 114.1 1 2 0 0.0024 14 0 0 0 3.77E+06 4.06E+06 - - - 2.8951 0.999 221125_WJC_METTL3_EV_vs_WT_F08.11315.11315.2 0.00427 30-Jun K.SSSTALTTNVTEQTEK.D sp|Q8WYP5|ELYS_HUMAN 1 1695.8163 1.17 115672 11315 2 1695.818024 848.9154 Protein ELYS OS=Homo sapiens OX=9606 GN=AHCTF1 PE=1 SV=3 4.53 2206.5 - 131581 - - - 1.0231 - 1.326 0.387 - 56.9 1 2 0 0.0017 16 0 0 0 2.77E+06 2.37E+06 - - - 2.5926 0.9997 221125_WJC_METTL3_EV_vs_WT_F08.11319.11319.3 0.000594 Dec-52 R.AHTSSTQLQEELEK[136.11].V sp|Q9Y6Y8|S23IP_HUMAN 1 1607.7882 0.53 115674 11319 3 1607.791763 536.9367 SEC23-interacting protein OS=Homo sapiens OX=9606 GN=SEC23IP PE=1 SV=1 4.75 2207 - 1.33E+06 - - - 2.1974 - 2.119 0.385 - 218.1 1 2 0 0.0035 14 0 0 0 1.26E+07 2.39E+07 - - - 4.827 1 221125_WJC_METTL3_EV_vs_WT_F08.11322.11322.3 6.95E-06 Dec-52 R.AHTSSTQLQEELEK.V sp|Q9Y6Y8|S23IP_HUMAN 1 1599.774 0.52 115677 11322 3 1599.773756 534.2653 SEC23-interacting protein OS=Homo sapiens OX=9606 GN=SEC23IP PE=1 SV=1 4.75 2207.4 - 868972 - - - -0.1713 - 2.612 0.449 - 297.2 1 2 0 -0.0003 14 0 0 0 1.29E+07 2.50E+07 - - - 6.0974 0.9943 221125_WJC_METTL3_EV_vs_WT_F08.11336.11336.2 5.36E-07 26-Aug K.VEYSEEELKTHISK.G "sp|P12956|XRCC6_HUMAN,tr|B1AHC9|B1AHC9_HUMAN" 2 1690.8414 1.41 115689 11336 2 1690.843842 846.428 X-ray repair cross-complementing protein 6 OS=Homo sapiens OX=9606 GN=XRCC6 PE=1 SV=2 4.91 2209 - 173937 - - - 1.4555 - 1.975 0.379 - 99.9 1 2 1 0.0025 14 0 0 0 1.30E+06 9.26E+05 - - - 3.5474 0.9991 221125_WJC_METTL3_EV_vs_WT_F08.11337.11337.3 0.00418 Oct-76 K.EC[160.03]EPPSAGAAVTARPGQEIR.Q sp|Q9C0E8|LNP_HUMAN 1 2095.0117 0.72 115690 11337 3 2095.012299 699.3445 Endoplasmic reticulum junction formation protein lunapark OS=Homo sapiens OX=9606 GN=LNPK PE=1 SV=2 4.79 2209.1 - 173818 - - - 0.3093 - 1.717 0.315 - 78.7 1 2 0 0.0006 20 0 0 0 2.81E+06 3.92E+06 - - - 3.3632 0.9981 221125_WJC_METTL3_EV_vs_WT_F08.11340.11340.3 4.96E-08 14/48 H.KDSVFLSC[160.03]SEDNR.L "sp|Q9BQA1|MEP50_HUMAN,tr|H0Y711|H0Y711_HUMAN" 2 1555.6937 3.58 115691 11340 3 1555.695969 519.5718 Methylosome protein 50 OS=Homo sapiens OX=9606 GN=WDR77 PE=1 SV=1 4.56 2209.5 - 857875 - - - 1.4772 - 3.022 0.563 - 297 1 1 0 0.0023 13 0 0 0 1.06E+07 2.95E+06 - - - 7.8147 0.9992 221125_WJC_METTL3_EV_vs_WT_F08.11341.11341.4 0.0175 Dec-96 K.IINEVSKPLAHHIPVEK.L sp|P55145|MANF_HUMAN 1 1923.0942 0.63 115692 11341 4 1923.09635 481.7808 Mesencephalic astrocyte-derived neurotrophic factor OS=Homo sapiens OX=9606 GN=MANF PE=1 SV=3 6.92 2209.6 - 585415 - - - 1.1273 - 1.919 0.313 - 80.7 1 2 0 0.0022 17 0 0 0 5.96E+06 9.48E+06 - - - 2.1761 1 221125_WJC_METTL3_EV_vs_WT_F08.11343.11343.3 1.23E-09 17/56 R.RYDVVADC[160.03]SDNVPTR.Y sp|O95396|MOCS3_HUMAN 1 1765.8053 1.18 115694 11343 3 1765.800084 589.6091 Adenylyltransferase and sulfurtransferase MOCS3 OS=Homo sapiens OX=9606 GN=MOCS3 PE=1 SV=1 4.43 2209.9 - 594083 - - - -2.9805 - 3.775 0.639 - 487.6 1 2 0 -0.0053 15 0 0 0 7.07E+06 6.00E+06 - - - 9.129 1 221125_WJC_METTL3_EV_vs_WT_F08.11345.11345.3 3.47E-11 15/68 K.TTIHQLTMQKEEDTSGYR.A sp|P15924|DESP_HUMAN 1 2137.011 25.14 115696 11345 3 2137.012994 713.3443 Desmoplakin OS=Homo sapiens OX=9606 GN=DSP PE=1 SV=3 5.41 2210.2 - 343669 - - - 0.941 - 3.176 0.65 - 331.7 1 2 1 0.002 18 0 0 0 2.05E+06 8.16E+04 - - - 8.6639 0.9991 221125_WJC_METTL3_EV_vs_WT_F08.11349.11349.3 0.000299 Aug-76 K.EC[160.03]EPPSAGAAVTAR[166.11]PGQEIR[166.11].Q sp|Q9C0E8|LNP_HUMAN 1 2115.0282 0.72 115700 11349 3 2115.021174 706.0167 Endoplasmic reticulum junction formation protein lunapark OS=Homo sapiens OX=9606 GN=LNPK PE=1 SV=2 4.79 2210.7 - 232319 - - - -3.3177 - 1.576 0.444 - 67.4 1 2 0 -0.007 20 0 0 0 2.81E+06 3.92E+06 - - - 4.5918 0.855 221125_WJC_METTL3_EV_vs_WT_F08.11351.11351.2 0.607 26-Mar K.VEYSEEELK[136.11]THISK[136.11].G "sp|P12956|XRCC6_HUMAN,tr|B1AHC9|B1AHC9_HUMAN" 2 1706.8698 1.41 115702 11351 2 1706.869193 854.4422 X-ray repair cross-complementing protein 6 OS=Homo sapiens OX=9606 GN=XRCC6 PE=1 SV=2 4.91 2211 - 125211 - - - -0.3445 - 0.814 0.266 - 21.4 2 2 1 -0.0006 14 0 0 0 1.30E+06 9.26E+05 - - - 0.3546 0.9998 221125_WJC_METTL3_EV_vs_WT_F08.11359.11359.3 8.55E-05 20/48 K.HFSQGSALILHQR[166.11].L sp|P17028|ZNF24_HUMAN 1 1502.7982 0.79 115708 11359 3 1502.796242 501.94 Zinc finger protein 24 OS=Homo sapiens OX=9606 GN=ZNF24 PE=1 SV=4 9.76 2211.7 - 591772 - - - -1.2796 - 3.572 0.242 - 683.5 1 2 0 -0.0019 13 0 0 0 5.97E+06 7.59E+06 - - - 4.6893 0.9995 221125_WJC_METTL3_EV_vs_WT_F08.11362.11362.2 0.0126 14-May K.VGVNGFGR.L sp|P04406|G3P_HUMAN 1 804.4242 1 115711 11362 2 804.424503 403.2194 Glyceraldehyde-3-phosphate dehydrogenase OS=Homo sapiens OX=9606 GN=GAPDH PE=1 SV=3 9.72 2212 - 257460 - - - 0.3319 - 1.442 0.408 - 56.8 1 2 0 0.0003 8 0 0 0 3.93E+06 3.94E+06 - - - 3.1583 0.9997 221125_WJC_METTL3_EV_vs_WT_F08.11363.11363.2 0.00011 24-Jul R.SSSESYTQSFQSR[166.11].K "sp|Q9BTU6|P4K2A_HUMAN,tr|E9PAM4|E9PAM4_HUMAN" 2 1502.6513 0.41 115712 11363 2 1502.65318 752.3329 Phosphatidylinositol 4-kinase type 2-alpha OS=Homo sapiens OX=9606 GN=PI4K2A PE=1 SV=1 5.72 2212.2 - 138147 - - - 1.2604 - 1.632 0.522 - 131 1 2 0 0.0019 13 0 0 0 1.42E+06 3.48E+06 - - - 4.153 1 221125_WJC_METTL3_EV_vs_WT_F08.11369.11369.2 2.05E-08 16/30 K.TSSGDASSLSIEETNK.L "sp|O43290|SNUT1_HUMAN,tr|E9PQI8|E9PQI8_HUMAN" 2 1624.7428 2.78 115716 11369 2 1624.744149 813.3787 U4\U6.U5 tri-snRNP-associated protein 1 OS=Homo sapiens OX=9606 GN=SART1 PE=1 SV=1 4.14 2212.8 - 1.30E+06 - - - 0.8371 - 3.372 0.711 - 981.4 1 2 0 0.0014 16 0 0 0 2.78E+07 9.99E+06 - - - 7.2804 1 221125_WJC_METTL3_EV_vs_WT_F08.11370.11370.3 1.02E-09 20/60 R.RNEGVVGGEDYEEVDR.Y "sp|Q86UK7|ZN598_HUMAN,tr|H3BQQ2|H3BQQ2_HUMAN,tr|H3BPG6|H3BPG6_HUMAN" 3 1821.8129 0.64 115717 11370 3 1821.815118 608.2783 E3 ubiquitin-protein ligase ZNF598 OS=Homo sapiens OX=9606 GN=ZNF598 PE=1 SV=1 4.08 2212.9 - 1.08E+06 - - - 1.1983 - 3.94 0.693 - 754 1 2 0 0.0022 16 0 0 0 1.12E+07 1.75E+07 - - - 9.7839 0.9109 221125_WJC_METTL3_EV_vs_WT_F08.11371.11371.4 0.263 Sep-84 K.LGETYKDHENIVIAK.M "sp|P07237|PDIA1_HUMAN,tr|A0A7P0TA97|A0A7P0TA97_HUMAN,tr|A0A7P0T8C0|A0A7P0T8C0_HUMAN,tr|H7BZ94|H7BZ94_HUMAN,tr|B3KTQ9|B3KTQ9_HUMAN,tr|A0A7P0TA71|A0A7P0TA71_HUMAN,tr|I3L4M2|I3L4M2_HUMAN,tr|A0A7P0T9K9|A0A7P0T9K9_HUMAN,tr|H0Y3Z3|H0Y3Z3_HUMAN,tr|A0A7P0TA35|A0A7P0TA35_HUMAN,tr|A0A7P0TB26|A0A7P0TB26_HUMAN,tr|A0A7P0T9U6|A0A7P0T9U6_HUMAN,tr|I3L0S0|I3L0S0_HUMAN,tr|I3L3P5|I3L3P5_HUMAN,tr|A0A7P0T8J3|A0A7P0T8J3_HUMAN,tr|A0A7P0T8X1|A0A7P0T8X1_HUMAN" 16 1728.9046 1.27 115718 11371 4 1728.907301 433.2334 Protein disulfide-isomerase OS=Homo sapiens OX=9606 GN=P4HB PE=1 SV=3 5.45 2213.1 - 553477 - - - 1.5333 - 1.591 0.176 - 60 1 2 1 0.0027 15 0 0 0 1.23E+07 9.66E+06 - - - 0.9233 0.938 221125_WJC_METTL3_EV_vs_WT_F08.11373.11373.4 0.0801 Sep-84 K.LGETYK[136.11]DHENIVIAK[136.11].M "sp|P07237|PDIA1_HUMAN,tr|A0A7P0TA97|A0A7P0TA97_HUMAN,tr|A0A7P0T8C0|A0A7P0T8C0_HUMAN,tr|H7BZ94|H7BZ94_HUMAN,tr|B3KTQ9|B3KTQ9_HUMAN,tr|A0A7P0TA71|A0A7P0TA71_HUMAN,tr|I3L4M2|I3L4M2_HUMAN,tr|A0A7P0T9K9|A0A7P0T9K9_HUMAN,tr|H0Y3Z3|H0Y3Z3_HUMAN,tr|A0A7P0TA35|A0A7P0TA35_HUMAN,tr|A0A7P0TB26|A0A7P0TB26_HUMAN,tr|A0A7P0T9U6|A0A7P0T9U6_HUMAN,tr|I3L0S0|I3L0S0_HUMAN,tr|I3L3P5|I3L3P5_HUMAN,tr|A0A7P0T8J3|A0A7P0T8J3_HUMAN,tr|A0A7P0T8X1|A0A7P0T8X1_HUMAN" 16 1744.9331 1.26 115720 11373 4 1744.933567 437.2405 Protein disulfide-isomerase OS=Homo sapiens OX=9606 GN=P4HB PE=1 SV=3 5.45 2213.3 - 399432 - - - 0.2963 - 1.531 0.186 - 58.9 1 2 1 0.0005 15 0 0 0 1.24E+07 9.79E+06 - - - 0.9972 0.9999 221125_WJC_METTL3_EV_vs_WT_F08.11374.11374.3 0.00086 17/56 K.LGETYKDHENIVIAK.M "sp|P07237|PDIA1_HUMAN,tr|A0A7P0TA97|A0A7P0TA97_HUMAN,tr|A0A7P0T8C0|A0A7P0T8C0_HUMAN,tr|H7BZ94|H7BZ94_HUMAN,tr|B3KTQ9|B3KTQ9_HUMAN,tr|A0A7P0TA71|A0A7P0TA71_HUMAN,tr|I3L4M2|I3L4M2_HUMAN,tr|A0A7P0T9K9|A0A7P0T9K9_HUMAN,tr|H0Y3Z3|H0Y3Z3_HUMAN,tr|A0A7P0TA35|A0A7P0TA35_HUMAN,tr|A0A7P0TB26|A0A7P0TB26_HUMAN,tr|A0A7P0T9U6|A0A7P0T9U6_HUMAN,tr|I3L0S0|I3L0S0_HUMAN,tr|I3L3P5|I3L3P5_HUMAN,tr|A0A7P0T8J3|A0A7P0T8J3_HUMAN,tr|A0A7P0T8X1|A0A7P0T8X1_HUMAN" 16 1728.9046 1.34 115721 11374 3 1728.905913 577.3088 Protein disulfide-isomerase OS=Homo sapiens OX=9606 GN=P4HB PE=1 SV=3 5.45 2213.4 - 325800 - - - 0.7305 - 3.36 0.49 - 372.9 1 2 1 0.0013 15 0 0 0 9.50E+06 7.09E+06 - - - 7.1651 0.9994 221125_WJC_METTL3_EV_vs_WT_F08.11375.11375.3 1.61E-05 Dec-56 K.LGETYK[136.11]DHENIVIAK[136.11].M "sp|P07237|PDIA1_HUMAN,tr|A0A7P0TA97|A0A7P0TA97_HUMAN,tr|A0A7P0T8C0|A0A7P0T8C0_HUMAN,tr|H7BZ94|H7BZ94_HUMAN,tr|B3KTQ9|B3KTQ9_HUMAN,tr|A0A7P0TA71|A0A7P0TA71_HUMAN,tr|I3L4M2|I3L4M2_HUMAN,tr|A0A7P0T9K9|A0A7P0T9K9_HUMAN,tr|H0Y3Z3|H0Y3Z3_HUMAN,tr|A0A7P0TA35|A0A7P0TA35_HUMAN,tr|A0A7P0TB26|A0A7P0TB26_HUMAN,tr|A0A7P0T9U6|A0A7P0T9U6_HUMAN,tr|I3L0S0|I3L0S0_HUMAN,tr|I3L3P5|I3L3P5_HUMAN,tr|A0A7P0T8J3|A0A7P0T8J3_HUMAN,tr|A0A7P0T8X1|A0A7P0T8X1_HUMAN" 16 1744.9331 1.34 115722 11375 3 1744.936984 582.6516 Protein disulfide-isomerase OS=Homo sapiens OX=9606 GN=P4HB PE=1 SV=3 5.45 2213.6 - 300884 - - - 2.2545 - 2.586 0.42 - 166.3 1 2 1 0.0039 15 0 0 0 9.50E+06 7.09E+06 - - - 5.7007 0.9957 221125_WJC_METTL3_EV_vs_WT_F08.11376.11376.3 0.0122 Sep-56 K.DEPNSTPEK[136.11]TEQFYR[166.11].K "sp|O76021|RL1D1_HUMAN,tr|J3QSV6|J3QSV6_HUMAN,tr|I3L3C4|I3L3C4_HUMAN,tr|I3L234|I3L234_HUMAN,tr|I3L3U9|I3L3U9_HUMAN" 5 1857.85 2.88 115723 11376 3 1857.847996 620.2906 Ribosomal L1 domain-containing protein 1 OS=Homo sapiens OX=9606 GN=RSL1D1 PE=1 SV=3 4.41 2213.7 - 273806 - - - -1.0744 - 1.767 0.301 - 103.4 1 2 1 -0.002 15 0 0 0 1.58E+07 5.51E+06 - - - 3.3808 1 221125_WJC_METTL3_EV_vs_WT_F08.11379.11379.3 4.83E-08 16/52 R.GR[166.11]AQVQEFC[160.03]DYGTK[136.11].E "sp|Q86U44|MTA70_HUMAN,tr|H0YFV6|H0YFV6_HUMAN" 2 1675.7743 0.06 115724 11379 3 1675.777665 559.5987 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 6.06 2214.1 - 2.15E+06 - - - 1.9931 - 2.966 0.653 - 452 1 2 1 0.0033 14 0 0 0 2.22E+06 3.78E+07 - - - 8.7087 0.9999 221125_WJC_METTL3_EV_vs_WT_F08.11380.11380.3 2.79E-07 16/56 K.IK[136.11]GEHPGLSIGDVAK[136.11].K "sp|B2RPK0|HGB1A_HUMAN,sp|P09429|HMGB1_HUMAN,tr|Q5T7C4|Q5T7C4_HUMAN" 3 1535.8642 0.2 115725 11380 3 1535.860567 512.962 Putative high mobility group protein B1-like 1 OS=Homo sapiens OX=9606 GN=HMGB1P1 PE=5 SV=1 6.75 2214.2 - 1.07E+06 - - - -2.3928 - 3.003 0.591 - 186.8 1 2 1 -0.0037 15 0 0 0 2.44E+07 1.20E+08 - - - 7.9973 1 221125_WJC_METTL3_EV_vs_WT_F08.11382.11382.2 1.05E-11 16/30 K.TSSGDASSLSIEETNK[136.11].L "sp|O43290|SNUT1_HUMAN,tr|E9PQI8|E9PQI8_HUMAN" 2 1632.757 2.72 115727 11382 2 1632.756987 817.3858 U4\U6.U5 tri-snRNP-associated protein 1 OS=Homo sapiens OX=9606 GN=SART1 PE=1 SV=1 4.14 2214.5 - 696145 - - - -0.0012 - 3.43 0.662 - 978 1 2 0 0 16 0 0 0 2.72E+07 9.99E+06 - - - 6.9608 0.9956 221125_WJC_METTL3_EV_vs_WT_F08.11384.11384.4 0.00423 10/102 R.VVIDPQEKPSEEPLGDRR.T "sp|Q93075|TATD2_HUMAN,tr|H7C1W4|H7C1W4_HUMAN" 2 2063.0647 0.67 115729 11384 4 2063.071026 516.7735 Putative deoxyribonuclease TATDN2 OS=Homo sapiens OX=9606 GN=TATDN2 PE=1 SV=2 4.51 2214.7 - 303024 - - - 3.0503 - 2.047 0.282 - 64.7 1 2 0 0.0063 18 0 0 0 3.82E+06 5.72E+06 - - - 1.9242 1 221125_WJC_METTL3_EV_vs_WT_F08.11386.11386.3 1.61E-05 16/52 K.HQAFEAELSANQSR[166.11].L "sp|Q13813|SPTN1_HUMAN,tr|A0A0D9SF54|A0A0D9SF54_HUMAN,tr|A0A0D9SGF6|A0A0D9SGF6_HUMAN" 3 1596.752 1.46 115731 11386 3 1596.752586 533.2579 "Spectrin alpha chain, non-erythrocytic 1 OS=Homo sapiens OX=9606 GN=SPTAN1 PE=1 SV=3" 5.4 2215 - 246589 - - - 0.3651 - 2.727 0.514 - 492.3 1 2 0 0.0006 14 0 0 0 3.26E+07 2.22E+07 - - - 6.9365 0.9997 221125_WJC_METTL3_EV_vs_WT_F08.11387.11387.3 2.94E-08 14/52 K.HQAFEAELSANQSR.L "sp|Q13813|SPTN1_HUMAN,tr|A0A0D9SF54|A0A0D9SF54_HUMAN,tr|A0A0D9SGF6|A0A0D9SGF6_HUMAN" 3 1586.7437 1.4 115732 11387 3 1586.752186 529.9219 "Spectrin alpha chain, non-erythrocytic 1 OS=Homo sapiens OX=9606 GN=SPTAN1 PE=1 SV=3" 5.4 2215.1 - 219953 - - - 5.3273 - 2.928 0.576 - 327.5 1 2 0 0.0085 14 0 0 0 3.26E+07 2.33E+07 - - - 7.8145 1 221125_WJC_METTL3_EV_vs_WT_F08.11389.11389.2 1.95E-07 Aug-32 R.EDYDSVEQDGDEPGPQR.S sp|Q9Y5S9|RBM8A_HUMAN 1 1934.7766 2.9 115734 11389 2 1934.779592 968.3956 RNA-binding protein 8A OS=Homo sapiens OX=9606 GN=RBM8A PE=1 SV=1 3.62 2215.4 - 131706 - - - 1.5418 - 1.825 0.705 - 135.6 1 2 0 0.003 17 0 0 0 2.86E+06 9.85E+05 - - - 5.7262 0.9996 221125_WJC_METTL3_EV_vs_WT_F08.11394.11394.4 0.000218 15/84 K.IK[136.11]GEHPGLSIGDVAK[136.11].K "sp|B2RPK0|HGB1A_HUMAN,sp|P09429|HMGB1_HUMAN,tr|Q5T7C4|Q5T7C4_HUMAN" 3 1535.8642 0.16 115737 11394 4 1535.865592 384.9733 Putative high mobility group protein B1-like 1 OS=Homo sapiens OX=9606 GN=HMGB1P1 PE=5 SV=1 6.75 2215.9 - 1.28E+06 - - - 0.879 - 2.558 0.419 - 133.1 1 2 1 0.0014 15 0 0 0 6.48E+06 3.96E+07 - - - 3.2087 1 221125_WJC_METTL3_EV_vs_WT_F08.11395.11395.3 2.47E-06 Nov-52 R.TQQQVEAEVTNIK[136.11]K[136.11].T "sp|Q9H9Q2|CSN7B_HUMAN,tr|A0A087X1P5|A0A087X1P5_HUMAN,tr|J3KQ34|J3KQ34_HUMAN,tr|J3QT73|J3QT73_HUMAN" 4 1630.8861 1 115738 11395 3 1630.887486 544.636 COP9 signalosome complex subunit 7b OS=Homo sapiens OX=9606 GN=COPS7B PE=1 SV=1 5.81 2216 - 916899 - - - 0.8498 - 2.147 0.508 - 114.8 1 2 0 0.0014 14 0 0 0 8.78E+06 8.79E+06 - - - 6.2339 0.9998 221125_WJC_METTL3_EV_vs_WT_F08.11399.11399.4 6.63E-05 17/90 R.LGHGEEELETEK[136.11]DFSR[166.11].Y sp|O60306|AQR_HUMAN 1 1892.8871 1.7 115742 11399 4 1892.888734 474.2291 RNA helicase aquarius OS=Homo sapiens OX=9606 GN=AQR PE=1 SV=4 4.41 2216.5 - 698090 - - - 0.8601 - 2.238 0.474 - 203.6 1 2 1 0.0016 16 0 0 0 1.67E+07 9.81E+06 - - - 3.635 1 221125_WJC_METTL3_EV_vs_WT_F08.11402.11402.3 1.45E-08 21/64 R.IPHEPVINSSNVHVGSR[166.11].G sp|Q14966|ZN638_HUMAN 1 1850.9627 1.28 115745 11402 3 1850.961633 617.9948 Zinc finger protein 638 OS=Homo sapiens OX=9606 GN=ZNF638 PE=1 SV=2 6.92 2216.8 - 437911 - - - -0.557 - 3.374 0.599 - 705.7 1 2 0 -0.001 17 0 0 0 1.35E+07 1.06E+07 - - - 8.2902 0.9998 221125_WJC_METTL3_EV_vs_WT_F08.11406.11406.4 2.63E-07 18/90 K.NVMVEPHRHEGVFIC[160.03]R.G "sp|P22087|FBRL_HUMAN,tr|M0R0P1|M0R0P1_HUMAN,tr|M0R1H0|M0R1H0_HUMAN,tr|M0QXL5|M0QXL5_HUMAN,tr|M0R2Q4|M0R2Q4_HUMAN,tr|M0R2B0|M0R2B0_HUMAN,tr|M0R2U2|M0R2U2_HUMAN" 7 1978.9618 0.73 115747 11406 4 1978.963297 495.7477 rRNA 2'-O-methyltransferase fibrillarin OS=Homo sapiens OX=9606 GN=FBL PE=1 SV=2 6.92 2217.4 - 1.07E+06 - - - 0.7539 - 3.342 0.478 - 303.3 1 2 1 0.0015 16 0 0 0 1.06E+07 1.44E+07 - - - 3.8111 0.9999 221125_WJC_METTL3_EV_vs_WT_F08.11407.11407.4 3.82E-06 19/90 R.LGHGEEELETEKDFSR.Y sp|O60306|AQR_HUMAN 1 1874.8646 1.71 115748 11407 4 1874.866109 469.7234 RNA helicase aquarius OS=Homo sapiens OX=9606 GN=AQR PE=1 SV=4 4.41 2217.4 - 1.09E+06 - - - 0.7857 - 3.437 0.586 - 388.5 1 2 1 0.0015 16 0 0 0 1.64E+07 9.60E+06 - - - 4.761 0.999 221125_WJC_METTL3_EV_vs_WT_F08.11408.11408.4 0.0107 18/90 K.NVMVEPHR[166.11]HEGVFIC[160.03]R[166.11].G "sp|P22087|FBRL_HUMAN,tr|M0R0P1|M0R0P1_HUMAN,tr|M0R1H0|M0R1H0_HUMAN,tr|M0QXL5|M0QXL5_HUMAN,tr|M0R2Q4|M0R2Q4_HUMAN,tr|M0R2B0|M0R2B0_HUMAN,tr|M0R2U2|M0R2U2_HUMAN" 7 1998.9783 0.74 115749 11408 4 1998.979729 500.7519 rRNA 2'-O-methyltransferase fibrillarin OS=Homo sapiens OX=9606 GN=FBL PE=1 SV=2 6.92 2217.5 - 1.53E+06 - - - 0.6924 - 2.588 0.36 - 276.3 1 2 1 0.0014 16 0 0 0 1.06E+07 1.44E+07 - - - 2.694 1 221125_WJC_METTL3_EV_vs_WT_F08.11409.11409.3 1.92E-08 16/48 R.K[136.11]PAAVLK[136.11]PSDWEK[136.11].S sp|Q9H0D6|XRN2_HUMAN 1 1491.8512 1.12 115750 11409 3 1491.853438 498.291 5'-3' exoribonuclease 2 OS=Homo sapiens OX=9606 GN=XRN2 PE=1 SV=1 8.5 2217.6 - 1.29E+06 - - - 1.5236 - 2.836 0.574 - 267.9 1 2 0 0.0023 13 0 0 0 9.78E+07 8.70E+07 - - - 7.7651 1 221125_WJC_METTL3_EV_vs_WT_F08.11410.11410.3 0.000445 22/60 R.LGHGEEELETEKDFSR.Y sp|O60306|AQR_HUMAN 1 1874.8646 1.32 115751 11410 3 1874.865557 625.9622 RNA helicase aquarius OS=Homo sapiens OX=9606 GN=AQR PE=1 SV=4 4.41 2217.7 - 720927 - - - 0.4912 - 4.067 0.592 - 835.8 1 2 1 0.0009 16 0 0 0 6.85E+06 5.17E+06 - - - 8.7396 0.9985 221125_WJC_METTL3_EV_vs_WT_F08.11411.11411.3 1.21E-05 17/60 K.QNLNVDKDTTLPASAR.K sp|O75330|HMMR_HUMAN 1 1741.8959 0.78 115752 11411 3 1741.902219 581.6392 Hyaluronan mediated motility receptor OS=Homo sapiens OX=9606 GN=HMMR PE=1 SV=2 5.96 2217.9 - 683441 - - - 3.6414 - 2.798 0.416 - 238.2 1 2 1 0.0063 16 0 0 0 6.20E+06 7.91E+06 - - - 5.8163 1 221125_WJC_METTL3_EV_vs_WT_F08.11412.11412.3 3.87E-12 21/60 R.LGHGEEELETEK[136.11]DFSR[166.11].Y sp|O60306|AQR_HUMAN 1 1892.8871 1.33 115753 11412 3 1892.890768 631.9696 RNA helicase aquarius OS=Homo sapiens OX=9606 GN=AQR PE=1 SV=4 4.41 2218 - 665184 - - - 1.9346 - 3.768 0.622 - 883.3 1 2 1 0.0037 16 0 0 0 6.80E+06 5.12E+06 - - - 8.8774 1 221125_WJC_METTL3_EV_vs_WT_F08.11413.11413.3 3.71E-07 20/72 K.LGEVVNTHGPVEPDK[136.11]DNIR[166.11].Q "sp|P30419|NMT1_HUMAN,tr|A0A7I2V4Y5|A0A7I2V4Y5_HUMAN,tr|K7EN82|K7EN82_HUMAN,tr|A0A7I2V3X4|A0A7I2V3X4_HUMAN,tr|A0A7I2V539|A0A7I2V539_HUMAN,tr|A0A7I2V3U5|A0A7I2V3U5_HUMAN" 6 2106.0825 0.26 115754 11413 3 2106.081331 703.0348 Glycylpeptide N-tetradecanoyltransferase 1 OS=Homo sapiens OX=9606 GN=NMT1 PE=1 SV=2 4.75 2218.1 - 604818 - - - -0.5323 - 4.06 0.596 - 591.3 1 2 1 -0.0011 19 0 0 0 1.72E+06 6.55E+06 - - - 8.6269 0.9991 221125_WJC_METTL3_EV_vs_WT_F08.11418.11418.2 0.000101 26-Aug K.HQAFEAELSANQSR.L "sp|Q13813|SPTN1_HUMAN,tr|A0A0D9SF54|A0A0D9SF54_HUMAN,tr|A0A0D9SGF6|A0A0D9SGF6_HUMAN" 3 1586.7437 1.81 115759 11418 2 1586.749027 794.3791 "Spectrin alpha chain, non-erythrocytic 1 OS=Homo sapiens OX=9606 GN=SPTAN1 PE=1 SV=3" 5.4 2218.8 - 170643 - - - 3.3364 - 2.135 0.473 - 156.2 1 2 0 0.0053 14 0 0 0 2.84E+06 1.57E+06 - - - 4.4362 1 221125_WJC_METTL3_EV_vs_WT_F08.11424.11424.4 1.55E-07 Dec-72 R.IHQESELHSYLSR[166.11].L "sp|Q9UNE7|CHIP_HUMAN,tr|H3BUD0|H3BUD0_HUMAN,tr|H3BS86|H3BS86_HUMAN,tr|H3BTA3|H3BTA3_HUMAN" 4 1607.7931 0.31 115763 11424 4 1607.793103 402.9556 E3 ubiquitin-protein ligase CHIP OS=Homo sapiens OX=9606 GN=STUB1 PE=1 SV=2 6 2219.5 - 1.13E+06 - - - -0.0224 - 2.986 0.499 - 189.5 1 2 0 0 13 0 0 0 7.05E+06 2.29E+07 - - - 3.9749 1 221125_WJC_METTL3_EV_vs_WT_F08.11425.11425.4 7.26E-08 20/96 R.IPHEPVINSSNVHVGSR[166.11].G sp|Q14966|ZN638_HUMAN 1 1850.9627 1.24 115764 11425 4 1850.962617 463.7479 Zinc finger protein 638 OS=Homo sapiens OX=9606 GN=ZNF638 PE=1 SV=2 6.92 2219.6 - 2.98E+06 - - - -0.0254 - 3.365 0.525 - 448.5 1 2 0 0 17 0 0 0 3.53E+07 2.85E+07 - - - 4.2169 1 221125_WJC_METTL3_EV_vs_WT_F08.11426.11426.4 0.000302 17/96 R.IPHEPVINSSNVHVGSR.G sp|Q14966|ZN638_HUMAN 1 1840.9544 1.24 115765 11426 4 1840.955946 461.2459 Zinc finger protein 638 OS=Homo sapiens OX=9606 GN=ZNF638 PE=1 SV=2 6.92 2219.6 - 2.84E+06 - - - 0.843 - 3.348 0.481 - 246.9 1 2 0 0.0016 17 0 0 0 3.55E+07 2.85E+07 - - - 3.8317 0.9996 221125_WJC_METTL3_EV_vs_WT_F08.11428.11428.3 0.000576 Nov-60 K.NVMVEPHR[166.11]HEGVFIC[160.03]R[166.11].G "sp|P22087|FBRL_HUMAN,tr|M0R0P1|M0R0P1_HUMAN,tr|M0R1H0|M0R1H0_HUMAN,tr|M0QXL5|M0QXL5_HUMAN,tr|M0R2Q4|M0R2Q4_HUMAN,tr|M0R2B0|M0R2B0_HUMAN,tr|M0R2U2|M0R2U2_HUMAN" 7 1998.9783 1.88 115767 11428 3 1998.97836 667.3334 rRNA 2'-O-methyltransferase fibrillarin OS=Homo sapiens OX=9606 GN=FBL PE=1 SV=2 6.92 2219.8 - 346744 - - - 0.0075 - 2.135 0.429 - 160.6 1 2 1 0 16 0 0 0 4.00E+06 2.13E+06 - - - 5.269 0.998 221125_WJC_METTL3_EV_vs_WT_F08.11430.11430.3 0.076 Jul-72 K.IEENSLK[136.11]EEESIEGEK[136.11]EVK[136.11].S "sp|Q14839|CHD4_HUMAN,tr|A0A2R8Y4X2|A0A2R8Y4X2_HUMAN,tr|A0A2U3TZM0|A0A2U3TZM0_HUMAN,tr|A0A2R8Y5M9|A0A2R8Y5M9_HUMAN,tr|A0A2R8Y445|A0A2R8Y445_HUMAN,tr|A0A2R8YD40|A0A2R8YD40_HUMAN,tr|A0A2R8Y5J0|A0A2R8Y5J0_HUMAN,tr|A0A2R8Y425|A0A2R8Y425_HUMAN,tr|A0A2R8YFK9|A0A2R8YFK9_HUMAN,tr|A0A2R8Y8C1|A0A2R8Y8C1_HUMAN,tr|A0A0C4DGG9|A0A0C4DGG9_HUMAN,tr|A0A2R8YFD8|A0A2R8YFD8_HUMAN,tr|A0A2R8YDW2|A0A2R8YDW2_HUMAN,tr|A0A2R8Y7I0|A0A2R8Y7I0_HUMAN,tr|F5GWX5|F5GWX5_HUMAN,tr|A0A2R8YER1|A0A2R8YER1_HUMAN,tr|A0A2R8Y7M9|A0A2R8Y7M9_HUMAN,tr|A0A2R8Y521|A0A2R8Y521_HUMAN,tr|A0A2R8YDJ9|A0A2R8YDJ9_HUMAN,tr|A0A2R8Y212|A0A2R8Y212_HUMAN,tr|A0A2R8YE38|A0A2R8YE38_HUMAN" 21 2242.1279 0.8 115769 11430 3 2242.126572 748.3832 Chromodomain-helicase-DNA-binding protein 4 OS=Homo sapiens OX=9606 GN=CHD4 PE=1 SV=2 4.27 2220.1 - 209795 - - - -0.5713 - 1.61 0.377 - 44.8 1 2 2 -0.0013 19 0 0 0 9.50E+05 1.19E+06 - - - 3.9128 1 221125_WJC_METTL3_EV_vs_WT_F08.11435.11435.3 7.01E-09 20/48 R.KPAAVLKPSDWEK.S sp|Q9H0D6|XRN2_HUMAN 1 1467.8086 1.12 115773 11435 3 1467.80949 490.2768 5'-3' exoribonuclease 2 OS=Homo sapiens OX=9606 GN=XRN2 PE=1 SV=1 8.5 2220.5 - 1.91E+06 - - - 0.6302 - 3.539 0.649 - 509.4 1 2 0 0.0009 13 0 0 0 9.78E+07 8.70E+07 - - - 9.2021 1 221125_WJC_METTL3_EV_vs_WT_F08.11436.11436.3 4.69E-07 18/64 R.IPHEPVINSSNVHVGSR.G sp|Q14966|ZN638_HUMAN 1 1840.9544 1.17 115774 11436 3 1840.95667 614.6587 Zinc finger protein 638 OS=Homo sapiens OX=9606 GN=ZNF638 PE=1 SV=2 6.92 2220.6 - 1.14E+06 - - - 1.2363 - 3.429 0.579 - 377.4 1 2 0 0.0023 17 0 0 0 1.41E+07 1.21E+07 - - - 8.1077 0.8887 221125_WJC_METTL3_EV_vs_WT_F08.11437.11437.4 0.566 Aug-72 R.YTIHSQLEHLQSK[136.11].Y sp|Q9BWJ5|SF3B5_HUMAN 1 1590.8246 1.29 115775 11437 4 1590.827998 398.7134 Splicing factor 3B subunit 5 OS=Homo sapiens OX=9606 GN=SF3B5 PE=1 SV=1 6.92 2220.7 - 896820 - - - 2.1637 - 1.393 0.135 - 28 1 2 0 0.0034 13 0 0 0 1.79E+07 1.39E+07 - - - 0.523 0.9986 221125_WJC_METTL3_EV_vs_WT_F08.11440.11440.3 0.000194 13/76 K.GEPGGGPGELAPVGPDEKEK.G sp|P55316|FOXG1_HUMAN 1 1918.9272 6.11 115778 11440 3 1918.93203 640.6497 Forkhead box protein G1 OS=Homo sapiens OX=9606 GN=FOXG1 PE=1 SV=2 4.25 2221.1 - 315492 - - - 2.4983 - 2.537 0.385 - 175.4 1 2 1 0.0048 20 0 0 0 5.40E+07 8.84E+06 - - - 5.0896 0.9988 221125_WJC_METTL3_EV_vs_WT_F08.11442.11442.3 1.74E-05 Nov-60 R.NFNIHSSISHESPAVK[136.11].L sp|O00311|CDC7_HUMAN 1 1773.8889 0.67 115780 11442 3 1773.896609 592.3036 Cell division cycle 7-related protein kinase OS=Homo sapiens OX=9606 GN=CDC7 PE=1 SV=1 6.92 2221.3 - 292426 - - - 4.3193 - 2.082 0.414 - 122.4 1 2 0 0.0077 16 0 0 0 2.01E+06 3.01E+06 - - - 5.0352 0.9982 221125_WJC_METTL3_EV_vs_WT_F08.11443.11443.2 2.23E-05 28-Oct K.IK[136.11]GEHPGLSIGDVAK[136.11].K "sp|B2RPK0|HGB1A_HUMAN,sp|P09429|HMGB1_HUMAN,tr|Q5T7C4|Q5T7C4_HUMAN" 3 1535.8642 0.001 115781 11443 2 1535.863544 768.9394 Putative high mobility group protein B1-like 1 OS=Homo sapiens OX=9606 GN=HMGB1P1 PE=5 SV=1 6.75 2221.4 - 290242 - - - -0.4545 - 2.192 0.467 - 234.6 1 2 1 -0.0007 15 0 0 0 0.00E+00 2.25E+06 - - - 4.4195 0.8017 221125_WJC_METTL3_EV_vs_WT_F08.11444.11444.4 1.48 Sep-90 R.NFNIHSSISHESPAVK.L sp|O00311|CDC7_HUMAN 1 1765.8747 0.47 115782 11444 4 1765.877238 442.476 Cell division cycle 7-related protein kinase OS=Homo sapiens OX=9606 GN=CDC7 PE=1 SV=1 6.92 2221.6 - 288881 - - - 1.4106 - 1.135 0.104 - 30 1 2 0 0.0025 16 0 0 0 3.26E+06 6.91E+06 - - - 0.1751 0.9998 221125_WJC_METTL3_EV_vs_WT_F08.11446.11446.2 2.93E-05 26-Oct K.HQAFEAELSANQSR[166.11].L "sp|Q13813|SPTN1_HUMAN,tr|A0A0D9SF54|A0A0D9SF54_HUMAN,tr|A0A0D9SGF6|A0A0D9SGF6_HUMAN" 3 1596.752 1.81 115784 11446 2 1596.749446 799.3833 "Spectrin alpha chain, non-erythrocytic 1 OS=Homo sapiens OX=9606 GN=SPTAN1 PE=1 SV=3" 5.4 2221.8 - 185759 - - - -1.6014 - 2.097 0.615 - 264.7 1 2 0 -0.0026 14 0 0 0 2.84E+06 1.57E+06 - - - 5.4409 0.9911 221125_WJC_METTL3_EV_vs_WT_F08.11447.11447.2 2.94E-07 Sep-40 R.SDSPVPTAPTSGGPK[136.11]PSTASA.V "sp|Q86U44|MTA70_HUMAN,tr|B4E349|B4E349_HUMAN,tr|F5H6D8|F5H6D8_HUMAN,tr|B4DTN4|B4DTN4_HUMAN" 4 1918.9364 0.04 115785 11447 2 1918.934339 960.4755 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 5.55 2222 - 154528 - - - -1.0485 - 1.82 0.585 - 125.4 1 1 0 -0.002 21 0 0 0 1.36E+05 3.87E+06 - - - 4.8334 0.9986 221125_WJC_METTL3_EV_vs_WT_F08.11450.11450.3 0.0011 Oct-60 K.QNLNVDK[136.11]DTTLPASAR[166.11].K sp|O75330|HMMR_HUMAN 1 1759.9183 1.14 115787 11450 3 1759.918997 587.6467 Hyaluronan mediated motility receptor OS=Homo sapiens OX=9606 GN=HMMR PE=1 SV=2 5.96 2222.3 - 236645 - - - 0.3699 - 2.179 0.33 - 89.2 1 2 1 0.0006 16 0 0 0 5.15E+06 4.53E+06 - - - 4.2175 1 221125_WJC_METTL3_EV_vs_WT_F08.11453.11453.3 5.00E-08 15/60 R.DGQVINETSQHHDDLE.- sp|P08670|VIME_HUMAN 1 1835.7922 - 115789 11453 3 1835.792811 612.938 Vimentin OS=Homo sapiens OX=9606 GN=VIM PE=1 SV=4 4.28 2222.6 - 2.16E+06 - - - 0.3334 - 3.16 0.561 - 341.6 1 2 0 0.0006 16 0 0 0 - - - - - 7.7466 0.9599 221125_WJC_METTL3_EV_vs_WT_F08.11456.11456.3 0.0403 Aug-52 K.HIGYDDSSKGFDYK.T sp|P31153|METK2_HUMAN 1 1630.7264 0.31 115792 11456 3 1630.727013 544.5827 S-adenosylmethionine synthase isoform type-2 OS=Homo sapiens OX=9606 GN=MAT2A PE=1 SV=1 5.3 2222.9 - 289432 - - - 0.406 - 1.211 0.253 - 68.6 1 2 1 0.0007 14 0 0 0 4.90E+06 1.56E+07 - - - 1.8693 0.9994 221125_WJC_METTL3_EV_vs_WT_F08.11457.11457.3 0.000777 Nov-60 R.NFNIHSSISHESPAVK.L sp|O00311|CDC7_HUMAN 1 1765.8747 0.68 115793 11457 3 1765.872469 589.6322 Cell division cycle 7-related protein kinase OS=Homo sapiens OX=9606 GN=CDC7 PE=1 SV=1 6.92 2223 - 261156 - - - -1.29 - 2.078 0.298 - 98.3 1 2 0 -0.0023 16 0 0 0 2.01E+06 2.95E+06 - - - 3.7385 0.9995 221125_WJC_METTL3_EV_vs_WT_F08.11459.11459.2 6.75E-05 24-Sep R.IHQESELHSYLSR[166.11].L "sp|Q9UNE7|CHIP_HUMAN,tr|H3BUD0|H3BUD0_HUMAN,tr|H3BS86|H3BS86_HUMAN,tr|H3BTA3|H3BTA3_HUMAN" 4 1607.7931 0.001 115795 11459 2 1607.793942 804.9038 E3 ubiquitin-protein ligase CHIP OS=Homo sapiens OX=9606 GN=STUB1 PE=1 SV=2 6 2223.3 - 145441 - - - 0.4994 - 2.044 0.302 - 239.1 1 2 0 0.0008 13 0 0 0 0.00E+00 9.09E+05 - - - 3.1062 0.9999 221125_WJC_METTL3_EV_vs_WT_F08.11460.11460.2 7.35E-06 28-Jun K.DSSYPYSQSDQSMNR[166.11].H sp|O95429|BAG4_HUMAN 1 1773.714 0.001 115796 11460 2 1773.715455 887.8643 BAG family molecular chaperone regulator 4 OS=Homo sapiens OX=9606 GN=BAG4 PE=1 SV=1 4.21 2223.4 - 92284.4 - - - 0.8417 - 1.624 0.638 - 78.3 1 2 0 0.0015 15 0 0 0 0.00E+00 1.74E+06 - - - 4.9449 1 221125_WJC_METTL3_EV_vs_WT_F08.11463.11463.3 1.93E-07 16/48 R.YTIHSQLEHLQSK[136.11].Y sp|Q9BWJ5|SF3B5_HUMAN 1 1590.8246 1.3 115797 11463 3 1590.827155 531.2821 Splicing factor 3B subunit 5 OS=Homo sapiens OX=9606 GN=SF3B5 PE=1 SV=1 6.92 2223.8 - 2.54E+06 - - - 1.6337 - 2.847 0.518 - 279.4 1 2 0 0.0026 13 0 0 0 3.20E+07 2.45E+07 - - - 7.1512 1 221125_WJC_METTL3_EV_vs_WT_F08.11464.11464.3 9.82E-11 17/56 R.IDEYDYSK[136.11]PIQGQQK[136.11].K "sp|P31040|SDHA_HUMAN,tr|A0A087X1I3|A0A087X1I3_HUMAN,tr|D6RFM5|D6RFM5_HUMAN" 3 1826.9021 0.47 115798 11464 3 1826.90417 609.9747 "Succinate dehydrogenase [ubiquinone] flavoprotein subunit, mitochondrial OS=Homo sapiens OX=9606 GN=SDHA PE=1 SV=2" 4.56 2223.9 - 1.84E+06 - - - 1.109 - 3.022 0.665 - 331.5 1 2 0 0.002 15 0 0 0 3.77E+07 8.06E+07 - - - 8.8393 0.9998 221125_WJC_METTL3_EV_vs_WT_F08.11465.11465.3 0.00438 15/56 K.IKGEHPGLSIGDVAK.K "sp|B2RPK0|HGB1A_HUMAN,sp|P09429|HMGB1_HUMAN,tr|Q5T7C4|Q5T7C4_HUMAN" 3 1519.8358 0.2 115799 11465 3 1519.838459 507.6192 Putative high mobility group protein B1-like 1 OS=Homo sapiens OX=9606 GN=HMGB1P1 PE=5 SV=1 6.75 2223.9 - 1.39E+06 - - - 1.7219 - 2.934 0.487 - 197.3 1 2 1 0.0026 15 0 0 0 2.44E+07 1.20E+08 - - - 6.7775 0.9899 221125_WJC_METTL3_EV_vs_WT_F08.11472.11472.3 0.000955 17/56 R.QR[166.11]EELGQGLQGVEQK[136.11].V sp|Q07065|CKAP4_HUMAN 1 1715.8921 1.03 115805 11472 3 1715.90199 572.9713 Cytoskeleton-associated protein 4 OS=Homo sapiens OX=9606 GN=CKAP4 PE=1 SV=2 4.79 2224.8 - 498454 - - - 5.7451 - 2.849 0.371 - 474.4 1 2 1 0.0099 15 0 0 0 3.99E+07 3.89E+07 - - - 5.4055 0.9999 221125_WJC_METTL3_EV_vs_WT_F08.11473.11473.3 4.51E-08 17/56 R.QREELGQGLQGVEQK.V sp|Q07065|CKAP4_HUMAN 1 1697.8697 1.04 115806 11473 3 1697.869512 566.9638 Cytoskeleton-associated protein 4 OS=Homo sapiens OX=9606 GN=CKAP4 PE=1 SV=2 4.79 2224.9 - 487619 - - - -0.0883 - 3.408 0.445 - 487.6 1 2 1 -0.0001 15 0 0 0 3.98E+07 3.83E+07 - - - 6.7007 0.9563 221125_WJC_METTL3_EV_vs_WT_F08.11482.11482.4 0.00787 Oct-96 L.LQDDAHPTLVTYADHSK[136.11].L "sp|Q86U44|MTA70_HUMAN,tr|F5H6D8|F5H6D8_HUMAN,tr|H0YFV6|H0YFV6_HUMAN,tr|B4DTN4|B4DTN4_HUMAN" 4 1917.9312 0.08 115813 11482 4 1917.932333 480.4901 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 5.13 2225.9 - 2.76E+06 - - - 0.5876 - 1.898 0.349 - 65.2 1 1 0 0.0011 17 0 0 0 4.62E+06 5.98E+07 - - - 2.4859 0.9973 221125_WJC_METTL3_EV_vs_WT_F08.11483.11483.3 0.000829 15/48 R.IHQESELHSYLSR.L "sp|Q9UNE7|CHIP_HUMAN,tr|H3BUD0|H3BUD0_HUMAN,tr|H3BS86|H3BS86_HUMAN,tr|H3BTA3|H3BTA3_HUMAN" 4 1597.7849 0.15 115814 11483 3 1597.795703 533.6022 E3 ubiquitin-protein ligase CHIP OS=Homo sapiens OX=9606 GN=STUB1 PE=1 SV=2 6 2226 - 742822 - - - 6.7806 - 2.588 0.427 - 383.2 1 2 0 0.0108 13 0 0 0 7.50E+06 4.94E+07 - - - 5.8758 0.9998 221125_WJC_METTL3_EV_vs_WT_F08.11487.11487.4 4.89E-05 Nov-84 R.VFYELQHSDKPVGTK.K "sp|Q93009|UBP7_HUMAN,tr|A0A669KBL1|A0A669KBL1_HUMAN,tr|F5H2X1|F5H2X1_HUMAN,tr|H3BND8|H3BND8_HUMAN" 4 1746.8941 0.96 115818 11487 4 1746.895081 437.7308 Ubiquitin carboxyl-terminal hydrolase 7 OS=Homo sapiens OX=9606 GN=USP7 PE=1 SV=2 6.72 2226.5 - 164238 - - - 0.5702 - 2.201 0.387 - 50.7 1 2 0 0.001 15 0 0 0 6.33E+06 6.59E+06 - - - 2.8765 0.9988 221125_WJC_METTL3_EV_vs_WT_F08.11491.11491.3 0.000358 13/48 R.EVQTNDLKEVVNK.L "sp|P61247|RS3A_HUMAN,tr|D6R9B6|D6R9B6_HUMAN,tr|H0Y9Y4|H0Y9Y4_HUMAN,tr|D6RB09|D6RB09_HUMAN,tr|E9PFI5|E9PFI5_HUMAN,tr|D6RAT0|D6RAT0_HUMAN,tr|D6RG13|D6RG13_HUMAN" 7 1514.794 0.99 115820 11491 3 1514.793987 505.9386 40S ribosomal protein S3a OS=Homo sapiens OX=9606 GN=RPS3A PE=1 SV=2 4.68 2227 - 1.28E+06 - - - -0.033 - 2.121 0.339 - 170.1 1 2 1 -0.0001 13 0 0 0 1.82E+07 1.83E+07 - - - 4.3581 0.9959 221125_WJC_METTL3_EV_vs_WT_F08.11492.11492.3 3.51E-06 Dec-36 R.K[136.11]IELFGR[166.11]PHN.V sp|Q86U44|MTA70_HUMAN 1 1227.6843 0.06 115821 11492 3 1227.68615 410.2354 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 8.75 2227.1 - 674589 - - - 1.4979 - 2.584 0.477 - 145.9 1 1 0 0.0018 10 0 0 0 8.34E+05 1.33E+07 - - - 6.6301 0.9995 221125_WJC_METTL3_EV_vs_WT_F08.11495.11495.3 3.43E-08 15/76 M.VEK[136.11]EEAGGGISEEEAAQYDR[166.11].Q "sp|Q9UBE0|SAE1_HUMAN,tr|B3KNJ4|B3KNJ4_HUMAN,tr|M0QZS6|M0QZS6_HUMAN,tr|A0A590UKC5|A0A590UKC5_HUMAN,tr|A0A590UK93|A0A590UK93_HUMAN,tr|M0R375|M0R375_HUMAN" 6 2183.9938 1.21 115824 11495 3 2184.002125 729.0052 SUMO-activating enzyme subunit 1 OS=Homo sapiens OX=9606 GN=SAE1 PE=1 SV=1 4.06 2227.4 - 236399 - - - 3.832 - 2.736 0.581 - 222.2 1 2 1 0.0084 20 0 0 0 2.12E+06 1.76E+06 - - - 7.457 0.9482 221125_WJC_METTL3_EV_vs_WT_F08.11497.11497.2 0.00395 24-Jul R.EVQTNDLK[136.11]EVVNK[136.11].L "sp|P61247|RS3A_HUMAN,tr|D6R9B6|D6R9B6_HUMAN,tr|H0Y9Y4|H0Y9Y4_HUMAN,tr|D6RB09|D6RB09_HUMAN,tr|E9PFI5|E9PFI5_HUMAN,tr|D6RAT0|D6RAT0_HUMAN,tr|D6RG13|D6RG13_HUMAN" 7 1530.8224 1.04 115826 11497 2 1530.828052 766.4185 40S ribosomal protein S3a OS=Homo sapiens OX=9606 GN=RPS3A PE=1 SV=2 4.68 2227.7 - 124202 - - - 3.668 - 1.558 0.35 - 134 1 2 1 0.0056 13 0 0 0 9.16E+05 8.82E+05 - - - 2.7623 0.9995 221125_WJC_METTL3_EV_vs_WT_F08.11500.11500.3 5.64E-05 14/48 R.EVQTNDLK[136.11]EVVNK[136.11].L "sp|P61247|RS3A_HUMAN,tr|D6R9B6|D6R9B6_HUMAN,tr|H0Y9Y4|H0Y9Y4_HUMAN,tr|D6RB09|D6RB09_HUMAN,tr|E9PFI5|E9PFI5_HUMAN,tr|D6RAT0|D6RAT0_HUMAN,tr|D6RG13|D6RG13_HUMAN" 7 1530.8224 0.99 115827 11500 3 1530.827591 511.2814 40S ribosomal protein S3a OS=Homo sapiens OX=9606 GN=RPS3A PE=1 SV=2 4.68 2228.1 - 1.65E+06 - - - 3.3668 - 2.827 0.497 - 230.2 1 2 1 0.0052 13 0 0 0 1.82E+07 1.83E+07 - - - 6.8972 0.9999 221125_WJC_METTL3_EV_vs_WT_F08.11501.11501.4 2.31E-05 Dec-84 R.VFYELQHSDK[136.11]PVGTK[136.11].K "sp|Q93009|UBP7_HUMAN,tr|A0A669KBL1|A0A669KBL1_HUMAN,tr|F5H2X1|F5H2X1_HUMAN,tr|H3BND8|H3BND8_HUMAN" 4 1762.9225 0.96 115828 11501 4 1762.923082 441.7379 Ubiquitin carboxyl-terminal hydrolase 7 OS=Homo sapiens OX=9606 GN=USP7 PE=1 SV=2 6.72 2228.3 - 536477 - - - 0.3386 - 2.242 0.464 - 72 1 2 0 0.0006 15 0 0 0 6.33E+06 6.59E+06 - - - 3.5534 0.9999 221125_WJC_METTL3_EV_vs_WT_F08.11503.11503.2 1.20E-08 30-Aug R.DGQVINETSQHHDDLE.- sp|P08670|VIME_HUMAN 1 1835.7922 - 115830 11503 2 1835.794922 918.9034 Vimentin OS=Homo sapiens OX=9606 GN=VIM PE=1 SV=4 4.28 2228.5 - 352562 - - - 1.4833 - 2.083 0.653 - 136 1 2 0 0.0027 16 0 0 0 - - - - - 5.6673 1 221125_WJC_METTL3_EV_vs_WT_F08.11506.11506.2 5.64E-11 28-Dec R.IDEYDYSK[136.11]PIQGQQK[136.11].K "sp|P31040|SDHA_HUMAN,tr|A0A087X1I3|A0A087X1I3_HUMAN,tr|D6RFM5|D6RFM5_HUMAN" 3 1826.9021 0.25 115833 11506 2 1826.900596 914.4583 "Succinate dehydrogenase [ubiquinone] flavoprotein subunit, mitochondrial OS=Homo sapiens OX=9606 GN=SDHA PE=1 SV=2" 4.56 2228.9 - 181274 - - - -0.8473 - 2.596 0.695 - 386.8 1 2 0 -0.0015 15 0 0 0 4.89E+05 1.96E+06 - - - 6.5192 0.9998 221125_WJC_METTL3_EV_vs_WT_F08.11507.11507.3 0.000599 Dec-76 R.ASAGHVAVSSPTPETGPLQR.L sp|P42695|CNDD3_HUMAN 1 1960.9967 1.89 115834 11507 3 1961.001457 654.6728 Condensin-2 complex subunit D3 OS=Homo sapiens OX=9606 GN=NCAPD3 PE=1 SV=2 6.79 2229 - 173714 - - - 2.4498 - 2.657 0.413 - 150.8 1 2 0 0.0048 20 0 0 0 2.07E+07 1.10E+07 - - - 5.5139 1 221125_WJC_METTL3_EV_vs_WT_F08.11512.11512.3 7.81E-06 17/52 R.GHNTNVGAIVFHPK.S sp|O43172|PRP4_HUMAN 1 1489.779 2.9 115837 11512 3 1489.781938 497.6003 U4\U6 small nuclear ribonucleoprotein Prp4 OS=Homo sapiens OX=9606 GN=PRPF4 PE=1 SV=2 8.76 2229.7 - 6.63E+06 - - - 1.9748 - 3.027 0.533 - 432 1 2 0 0.0029 14 0 0 0 2.11E+08 7.28E+07 - - - 7.425 1 221125_WJC_METTL3_EV_vs_WT_F08.11513.11513.3 7.82E-08 15/48 K.KPLPDHVSIVEPK.D "sp|P23396|RS3_HUMAN,tr|H0YEU2|H0YEU2_HUMAN,tr|E9PSF4|E9PSF4_HUMAN,tr|E9PL09|E9PL09_HUMAN,tr|E9PPU1|E9PPU1_HUMAN" 5 1457.8242 0.71 115838 11513 3 1457.826869 486.9487 40S ribosomal protein S3 OS=Homo sapiens OX=9606 GN=RPS3 PE=1 SV=2 6.75 2229.7 - 1.30E+06 - - - 1.8205 - 2.848 0.51 - 296.1 1 2 0 0.0027 13 0 0 0 2.26E+07 3.17E+07 - - - 7.0629 1 221125_WJC_METTL3_EV_vs_WT_F08.11515.11515.3 4.70E-09 16/56 R.VFYELQHSDKPVGTK.K "sp|Q93009|UBP7_HUMAN,tr|A0A669KBL1|A0A669KBL1_HUMAN,tr|F5H2X1|F5H2X1_HUMAN,tr|H3BND8|H3BND8_HUMAN" 4 1746.8941 1.03 115840 11515 3 1746.899075 583.3053 Ubiquitin carboxyl-terminal hydrolase 7 OS=Homo sapiens OX=9606 GN=USP7 PE=1 SV=2 6.72 2230 - 631409 - - - 2.8565 - 3.029 0.569 - 333 1 2 0 0.005 15 0 0 0 6.52E+06 6.35E+06 - - - 7.7742 0.8391 221125_WJC_METTL3_EV_vs_WT_F08.11516.11516.4 0.382 Oct-72 R.TQFSDRDLATLKK.Y sp|Q7Z353|HDX_HUMAN 1 1521.8151 3.92 115841 11516 4 1521.816018 381.4611 Highly divergent homeobox OS=Homo sapiens OX=9606 GN=HDX PE=1 SV=1 8.26 2230.1 - 485037 - - - 0.5986 - 1.188 0.156 - 54.1 1 2 1 0.0009 13 0 0 0 6.81E+06 1.73E+06 - - - 0.6474 0.9999 221125_WJC_METTL3_EV_vs_WT_F08.11518.11518.3 1.87E-07 14/76 R.ASAGHVAVSSPTPETGPLQR[166.11].L sp|P42695|CNDD3_HUMAN 1 1971.0049 1.84 115843 11518 3 1971.00017 658.0089 Condensin-2 complex subunit D3 OS=Homo sapiens OX=9606 GN=NCAPD3 PE=1 SV=2 6.79 2230.4 - 318051 - - - -2.4115 - 2.776 0.503 - 184.6 1 2 0 -0.0048 20 0 0 0 2.01E+07 1.10E+07 - - - 6.6236 0.9271 221125_WJC_METTL3_EV_vs_WT_F08.11519.11519.3 0.000116 13/48 A.RDLDELSRYPEDK.L "sp|P43243|MATR3_HUMAN,tr|A8MXP9|A8MXP9_HUMAN,tr|D6R991|D6R991_HUMAN,tr|A0A0R4J2E8|A0A0R4J2E8_HUMAN,tr|D6REM6|D6REM6_HUMAN" 5 1634.79 1.71 115844 11519 3 1634.786928 545.9373 Matrin-3 OS=Homo sapiens OX=9606 GN=MATR3 PE=1 SV=2 4.44 2230.5 - 268181 - - - -1.8877 - 2.443 0.382 - 271 1 1 1 -0.0031 13 0 0 0 1.89E+07 1.10E+07 - - - 5.2199 1 221125_WJC_METTL3_EV_vs_WT_F08.11525.11525.3 2.09E-11 19/52 R.GHNTNVGAIVFHPK[136.11].S sp|O43172|PRP4_HUMAN 1 1497.7932 2.92 115849 11525 3 1497.795402 500.2717 U4\U6 small nuclear ribonucleoprotein Prp4 OS=Homo sapiens OX=9606 GN=PRPF4 PE=1 SV=2 8.76 2231.2 - 4.35E+06 - - - 1.4728 - 3.235 0.633 - 708.6 1 2 0 0.0022 14 0 0 0 2.11E+08 7.24E+07 - - - 8.7167 1 221125_WJC_METTL3_EV_vs_WT_F08.11526.11526.3 2.28E-06 14/60 K.ATAGDTHLGGEDFDNR[166.11].L "sp|P48741|HSP77_HUMAN,sp|P0DMV8|HS71A_HUMAN,sp|P34931|HS71L_HUMAN,sp|P0DMV9|HS71B_HUMAN,sp|P17066|HSP76_HUMAN,tr|Q53FA3|Q53FA3_HUMAN,tr|V9GZ37|V9GZ37_HUMAN,tr|A0A0G2JIW1|A0A0G2JIW1_HUMAN" 8 1684.7317 0.08 115850 11526 3 1684.731032 562.5845 Putative heat shock 70 kDa protein 7 OS=Homo sapiens OX=9606 GN=HSPA7 PE=5 SV=2 4.22 2231.4 - 526671 - - - -0.3734 - 2.421 0.486 - 241 1 2 0 -0.0006 16 0 0 0 8.11E+05 9.89E+06 - - - 6.2269 1 221125_WJC_METTL3_EV_vs_WT_F08.11528.11528.3 8.10E-09 33/92 K.SLAGSSGPGASSGTSGDHGELVVR[166.11].L "sp|P29692|EF1D_HUMAN,tr|E9PI39|E9PI39_HUMAN,tr|E9PMW7|E9PMW7_HUMAN,tr|E9PQ49|E9PQ49_HUMAN,tr|A0A087X1X7|A0A087X1X7_HUMAN,tr|E9PL12|E9PL12_HUMAN,tr|H0YCK7|H0YCK7_HUMAN,tr|E9PIZ1|E9PIZ1_HUMAN,tr|E9PPR1|E9PPR1_HUMAN,tr|E9PRY8|E9PRY8_HUMAN,tr|E9PK01|E9PK01_HUMAN" 11 2194.049 1.54 115852 11528 3 2194.05334 732.3569 Elongation factor 1-delta OS=Homo sapiens OX=9606 GN=EEF1D PE=1 SV=5 5.3 2231.6 - 817884 - - - 1.9904 - 5.443 0.558 - 989.7 1 2 0 0.0044 24 0 0 0 4.12E+08 2.68E+08 - - - 8.6952 1 221125_WJC_METTL3_EV_vs_WT_F08.11531.11531.3 9.74E-08 18/76 K.TPASGLQTPTSTPAPGSATR.T sp|Q96DF8|ESS2_HUMAN 1 1896.9541 1.4 115855 11531 3 1896.959148 633.3253 Splicing factor ESS-2 homolog OS=Homo sapiens OX=9606 GN=ESS2 PE=1 SV=1 9.41 2232 - 454060 - - - 2.6506 - 3.666 0.55 - 276.8 1 2 0 0.005 20 0 0 0 1.64E+07 1.17E+07 - - - 7.8222 0.9994 221125_WJC_METTL3_EV_vs_WT_F08.11533.11533.3 0.000393 16/76 K.TPASGLQTPTSTPAPGSATR[166.11].T sp|Q96DF8|ESS2_HUMAN 1 1906.9624 1.4 115857 11533 3 1906.96389 636.6614 Splicing factor ESS-2 homolog OS=Homo sapiens OX=9606 GN=ESS2 PE=1 SV=1 9.41 2232.2 - 206639 - - - 0.7866 - 2.432 0.268 - 224.4 1 2 0 0.0015 20 0 0 0 1.64E+07 1.17E+07 - - - 3.6836 0.9999 221125_WJC_METTL3_EV_vs_WT_F08.11538.11538.3 2.21E-05 Nov-56 K.KVEQTIQYNSELEQK.V "sp|Q8IWJ2|GCC2_HUMAN,tr|B8ZZW2|B8ZZW2_HUMAN" 2 1835.9265 1.46 115860 11538 3 1835.927357 612.9828 GRIP and coiled-coil domain-containing protein 2 OS=Homo sapiens OX=9606 GN=GCC2 PE=1 SV=4 4.79 2233 - 1.42E+06 - - - 0.4624 - 2.166 0.464 - 121.9 1 2 0 0.0008 15 0 0 0 1.27E+07 8.75E+06 - - - 5.7296 0.9999 221125_WJC_METTL3_EV_vs_WT_F08.11539.11539.3 0.002 16/32 R.EHLLDQLKR.K "sp|P52732|KIF11_HUMAN,tr|A0A7I2V3A9|A0A7I2V3A9_HUMAN" 2 1150.6459 4.47 115861 11539 3 1150.647293 384.5559 Kinesin-like protein KIF11 OS=Homo sapiens OX=9606 GN=KIF11 PE=1 SV=2 6.85 2233.1 - 948658 - - - 1.2489 - 3.078 0.341 - 537.3 1 2 0 0.0014 9 0 0 0 9.30E+07 2.08E+07 - - - 5.7298 0.9999 221125_WJC_METTL3_EV_vs_WT_F08.11541.11541.4 4.90E-06 18/114 R.DTHPGSPGSPGPALRPLPAR.E sp|Q8N0Y2|ZN444_HUMAN 1 1979.0337 1.66 115863 11541 4 1979.039501 495.7657 Zinc finger protein 444 OS=Homo sapiens OX=9606 GN=ZNF444 PE=1 SV=1 9.61 2233.3 - 726268 - - - 2.9277 - 3.108 0.539 - 171.5 1 2 0 0.0058 20 0 0 0 1.11E+07 6.68E+06 - - - 4.295 0.9994 221125_WJC_METTL3_EV_vs_WT_F08.11544.11544.3 0.089 Dec-32 R.EHLLDQLK[136.11]R[166.11].K "sp|P52732|KIF11_HUMAN,tr|A0A7I2V3A9|A0A7I2V3A9_HUMAN" 2 1168.6683 4.47 115866 11544 3 1168.669513 390.5634 Kinesin-like protein KIF11 OS=Homo sapiens OX=9606 GN=KIF11 PE=1 SV=2 6.85 2233.7 - 345128 - - - 1.0157 - 2.35 0.239 - 252 1 2 0 0.0012 9 0 0 0 9.29E+07 2.08E+07 - - - 3.7793 0.9997 221125_WJC_METTL3_EV_vs_WT_F08.11545.11545.3 0.00177 13/76 K.GEPGGGPGELAPVGPDEK[136.11]EK[136.11].G sp|P55316|FOXG1_HUMAN 1 1934.9556 4.68 115867 11545 3 1934.958031 645.9925 Forkhead box protein G1 OS=Homo sapiens OX=9606 GN=FOXG1 PE=1 SV=2 4.25 2233.8 - 333041 - - - 1.2378 - 2.609 0.433 - 185.4 1 2 1 0.0024 20 0 0 0 1.97E+07 4.21E+06 - - - 5.6933 1 221125_WJC_METTL3_EV_vs_WT_F08.11546.11546.2 1.62E-09 19/38 K.TPASGLQTPTSTPAPGSATR.T sp|Q96DF8|ESS2_HUMAN 1 1896.9541 1.98 115868 11546 2 1896.955848 949.4843 Splicing factor ESS-2 homolog OS=Homo sapiens OX=9606 GN=ESS2 PE=1 SV=1 9.41 2233.9 - 305885 - - - 0.9109 - 3.858 0.664 - 709.3 1 2 0 0.0017 20 0 0 0 1.11E+07 5.58E+06 - - - 7.2642 1 221125_WJC_METTL3_EV_vs_WT_F08.11550.11550.2 2.46E-09 17/38 K.TPASGLQTPTSTPAPGSATR[166.11].T sp|Q96DF8|ESS2_HUMAN 1 1906.9624 1.98 115872 11550 2 1906.962357 954.4885 Splicing factor ESS-2 homolog OS=Homo sapiens OX=9606 GN=ESS2 PE=1 SV=1 9.41 2234.4 - 200886 - - - -0.0173 - 3.072 0.624 - 519.4 1 2 0 0 20 0 0 0 1.11E+07 5.58E+06 - - - 6.4092 0.9986 221125_WJC_METTL3_EV_vs_WT_F08.11554.11554.3 8.35E-09 18/52 K.AYHPHC[160.03]FTC[160.03]VVC[160.03]AR.P "sp|Q15942|ZYX_HUMAN,tr|H0Y2Y8|H0Y2Y8_HUMAN,tr|C9JJK5|C9JJK5_HUMAN" 3 1776.7647 2.26 115874 11554 3 1776.765916 593.2622 Zyxin OS=Homo sapiens OX=9606 GN=ZYX PE=1 SV=1 8.01 2234.9 - 1.17E+06 - - - 0.6928 - 3.213 0.54 - 725.9 1 1 0 0.0012 14 0 0 0 1.10E+07 4.87E+06 - - - 7.662 0.9999 221125_WJC_METTL3_EV_vs_WT_F08.11555.11555.3 1.32E-05 Dec-44 R.SQQQQLVESLHK.V sp|Q7Z3B4|NUP54_HUMAN 1 1423.7419 2.04 115875 11555 3 1423.743683 475.5879 Nucleoporin p54 OS=Homo sapiens OX=9606 GN=NUP54 PE=1 SV=2 6.47 2235 - 1.09E+06 - - - 1.2228 - 2.26 0.459 - 252.6 1 2 0 0.0017 12 0 0 0 1.11E+07 5.42E+06 - - - 5.917 0.9997 221125_WJC_METTL3_EV_vs_WT_F08.11562.11562.2 7.61E-08 30-Oct K.TSSDNNVSVTNVSVAK.T "sp|P54132|BLM_HUMAN,tr|A0A7P0TBM9|A0A7P0TBM9_HUMAN,tr|A0A3B3IT82|A0A3B3IT82_HUMAN,tr|H0YNU5|H0YNU5_HUMAN,tr|H0YLV8|H0YLV8_HUMAN" 5 1620.7955 1.07 115882 11562 2 1620.799711 811.405 Bloom syndrome protein OS=Homo sapiens OX=9606 GN=BLM PE=1 SV=1 5.5 2235.8 - 230507 - - - 2.6018 - 2.181 0.599 - 242.9 1 2 0 0.0042 16 0 0 0 3.90E+06 3.65E+06 - - - 5.381 0.9996 221125_WJC_METTL3_EV_vs_WT_F08.11563.11563.3 0.000392 Aug-76 R.DTHPGSPGSPGPALR[166.11]PLPAR[166.11].E sp|Q8N0Y2|ZN444_HUMAN 1 1999.0502 2.8 115883 11563 3 1999.050033 667.3574 Zinc finger protein 444 OS=Homo sapiens OX=9606 GN=ZNF444 PE=1 SV=1 9.61 2235.9 - 163216 - - - -0.1071 - 1.711 0.379 - 41.9 1 2 0 -0.0002 20 0 0 0 4.05E+06 1.45E+06 - - - 4.0684 1 221125_WJC_METTL3_EV_vs_WT_F08.11566.11566.3 3.49E-07 19/48 K.K[136.11]PLPDHVSIVEPK[136.11].D "sp|P23396|RS3_HUMAN,tr|H0YEU2|H0YEU2_HUMAN,tr|E9PSF4|E9PSF4_HUMAN,tr|E9PL09|E9PL09_HUMAN,tr|E9PPU1|E9PPU1_HUMAN" 5 1473.8526 0.74 115885 11566 3 1473.855104 492.2915 40S ribosomal protein S3 OS=Homo sapiens OX=9606 GN=RPS3 PE=1 SV=2 6.75 2236.3 - 2.03E+06 - - - 1.6888 - 3.611 0.591 - 483.1 1 2 0 0.0025 13 0 0 0 4.67E+07 6.31E+07 - - - 8.6096 0.9999 221125_WJC_METTL3_EV_vs_WT_F08.11570.11570.3 5.61E-05 Dec-44 R.SQQQQLVESLHK[136.11].V sp|Q7Z3B4|NUP54_HUMAN 1 1431.7561 2.09 115888 11570 3 1431.756804 478.2593 Nucleoporin p54 OS=Homo sapiens OX=9606 GN=NUP54 PE=1 SV=2 6.47 2236.7 - 562083 - - - 0.4624 - 2.189 0.385 - 200.4 1 2 0 0.0007 12 0 0 0 1.13E+07 5.42E+06 - - - 5.0038 0.9997 221125_WJC_METTL3_EV_vs_WT_F08.11572.11572.4 1.27E-05 13/78 K.HQLLEADISAHEDR[166.11].L "sp|Q13813|SPTN1_HUMAN,tr|A0A0D9SF54|A0A0D9SF54_HUMAN,tr|A0A0D9SGF6|A0A0D9SGF6_HUMAN" 3 1642.7939 1.43 115890 11572 4 1642.798758 411.7057 "Spectrin alpha chain, non-erythrocytic 1 OS=Homo sapiens OX=9606 GN=SPTAN1 PE=1 SV=3" 4.72 2237 - 207172 - - - 2.9766 - 2.341 0.419 - 209.5 1 2 0 0.0049 14 0 0 0 1.15E+07 8.07E+06 - - - 3.1812 1 221125_WJC_METTL3_EV_vs_WT_F08.11579.11579.2 1.74E-07 Oct-46 K.SLAGSSGPGASSGTSGDHGELVVR[166.11].L "sp|P29692|EF1D_HUMAN,tr|E9PI39|E9PI39_HUMAN,tr|E9PMW7|E9PMW7_HUMAN,tr|E9PQ49|E9PQ49_HUMAN,tr|A0A087X1X7|A0A087X1X7_HUMAN,tr|E9PL12|E9PL12_HUMAN,tr|H0YCK7|H0YCK7_HUMAN,tr|E9PIZ1|E9PIZ1_HUMAN,tr|E9PPR1|E9PPR1_HUMAN,tr|E9PRY8|E9PRY8_HUMAN,tr|E9PK01|E9PK01_HUMAN" 11 2194.049 1.81 115895 11579 2 2194.050085 1098.0318 Elongation factor 1-delta OS=Homo sapiens OX=9606 GN=EEF1D PE=1 SV=5 5.3 2237.9 - 129796 - - - 0.5068 - 2.419 0.63 - 180.8 1 2 0 0.0011 24 0 0 0 3.65E+06 2.02E+06 - - - 5.8656 1 221125_WJC_METTL3_EV_vs_WT_F08.11584.11584.3 2.72E-12 22/52 K.HQLLEADISAHEDR[166.11].L "sp|Q13813|SPTN1_HUMAN,tr|A0A0D9SF54|A0A0D9SF54_HUMAN,tr|A0A0D9SGF6|A0A0D9SGF6_HUMAN" 3 1642.7939 1.64 115898 11584 3 1642.793947 548.6052 "Spectrin alpha chain, non-erythrocytic 1 OS=Homo sapiens OX=9606 GN=SPTAN1 PE=1 SV=3" 4.72 2238.6 - 1.44E+06 - - - 0.0481 - 4.327 0.682 - 1177.6 1 2 0 0.0001 14 0 0 0 4.11E+07 2.51E+07 - - - 10.0366 1 221125_WJC_METTL3_EV_vs_WT_F08.11585.11585.3 4.69E-06 13/56 K.GPNGVYDFSQAHNAK.D sp|Q9Y5V3|MAGD1_HUMAN 1 1603.7379 9.63 115899 11585 3 1603.739819 535.5866 Melanoma-associated antigen D1 OS=Homo sapiens OX=9606 GN=MAGED1 PE=1 SV=3 6.74 2238.7 - 373219 - - - 1.1847 - 2.153 0.504 - 171.9 1 2 0 0.0019 15 0 0 0 6.31E+06 6.55E+05 - - - 6.1596 0.9999 221125_WJC_METTL3_EV_vs_WT_F08.11588.11588.4 1.00E-14 23/90 K.IFVGGIKEDTEEHHLR.D "sp|Q32P51|RA1L2_HUMAN,sp|P09651|ROA1_HUMAN,sp|P22626|ROA2_HUMAN,tr|A0A7I2YQN4|A0A7I2YQN4_HUMAN,tr|A0A7I2YQX9|A0A7I2YQX9_HUMAN,tr|A0A7I2V4N0|A0A7I2V4N0_HUMAN,tr|A0A024RA28|A0A024RA28_HUMAN,tr|A0A7I2V4N1|A0A7I2V4N1_HUMAN,tr|A0A7I2V4I6|A0A7I2V4I6_HUMAN,tr|F8VZ49|F8VZ49_HUMAN,tr|A0A7I2V3R8|A0A7I2V3R8_HUMAN,tr|A0A087WUI2|A0A087WUI2_HUMAN,tr|A0A7I2V4S4|A0A7I2V4S4_HUMAN,tr|F8VTQ5|F8VTQ5_HUMAN,tr|F8W6I7|F8W6I7_HUMAN,tr|A0A7I2V2L6|A0A7I2V2L6_HUMAN,tr|A0A7I2V323|A0A7I2V323_HUMAN,tr|A0A7I2V3W0|A0A7I2V3W0_HUMAN,tr|A0A7I2V5U9|A0A7I2V5U9_HUMAN,tr|A0A2R8Y4L2|A0A2R8Y4L2_HUMAN,tr|A0A7I2V3P1|A0A7I2V3P1_HUMAN,tr|A0A7I2V3P7|A0A7I2V3P7_HUMAN" 22 1878.9588 1.24 115902 11588 4 1878.962688 470.747 Heterogeneous nuclear ribonucleoprotein A1-like 2 OS=Homo sapiens OX=9606 GN=HNRNPA1L2 PE=2 SV=2 5.36 2239.1 - 570754 - - - 2.0634 - 4.503 0.588 - 663 1 2 1 0.0039 16 0 0 0 8.20E+08 6.61E+08 - - - 4.8729 1 221125_WJC_METTL3_EV_vs_WT_F08.11590.11590.3 4.29E-06 13/60 K.STAGDTHLGGEDFDNR[166.11].M "sp|P54652|HSP72_HUMAN,sp|P11142|HSP7C_HUMAN,tr|E9PKE3|E9PKE3_HUMAN,tr|E9PN89|E9PN89_HUMAN" 4 1700.7266 0.14 115904 11590 3 1700.726946 567.9161 Heat shock-related 70 kDa protein 2 OS=Homo sapiens OX=9606 GN=HSPA2 PE=1 SV=1 4.22 2239.3 - 282007 - - - 0.2176 - 2.228 0.524 - 199.1 1 2 0 0.0004 16 0 0 0 1.36E+06 9.63E+06 - - - 6.4375 0.9999 221125_WJC_METTL3_EV_vs_WT_F08.11596.11596.4 0.000126 20/90 K.IFVGGIK[136.11]EDTEEHHLR[166.11].D "sp|Q32P51|RA1L2_HUMAN,sp|P09651|ROA1_HUMAN,sp|P22626|ROA2_HUMAN,tr|A0A7I2YQN4|A0A7I2YQN4_HUMAN,tr|A0A7I2YQX9|A0A7I2YQX9_HUMAN,tr|A0A7I2V4N0|A0A7I2V4N0_HUMAN,tr|A0A024RA28|A0A024RA28_HUMAN,tr|A0A7I2V4N1|A0A7I2V4N1_HUMAN,tr|A0A7I2V4I6|A0A7I2V4I6_HUMAN,tr|F8VZ49|F8VZ49_HUMAN,tr|A0A7I2V3R8|A0A7I2V3R8_HUMAN,tr|A0A087WUI2|A0A087WUI2_HUMAN,tr|A0A7I2V4S4|A0A7I2V4S4_HUMAN,tr|F8VTQ5|F8VTQ5_HUMAN,tr|F8W6I7|F8W6I7_HUMAN,tr|A0A7I2V2L6|A0A7I2V2L6_HUMAN,tr|A0A7I2V323|A0A7I2V323_HUMAN,tr|A0A7I2V3W0|A0A7I2V3W0_HUMAN,tr|A0A7I2V5U9|A0A7I2V5U9_HUMAN,tr|A0A2R8Y4L2|A0A2R8Y4L2_HUMAN,tr|A0A7I2V3P1|A0A7I2V3P1_HUMAN,tr|A0A7I2V3P7|A0A7I2V3P7_HUMAN" 22 1896.9813 1.24 115908 11596 4 1896.982541 475.2526 Heterogeneous nuclear ribonucleoprotein A1-like 2 OS=Homo sapiens OX=9606 GN=HNRNPA1L2 PE=2 SV=2 5.36 2240 - 3.24E+06 - - - 0.6642 - 3.715 0.58 - 402.7 1 2 1 0.0013 16 0 0 0 8.19E+08 6.61E+08 - - - 4.7363 0.9999 221125_WJC_METTL3_EV_vs_WT_F08.11597.11597.3 2.01E-06 16/44 R.TNTPVKEDWNVR.L "sp|P78347|GTF2I_HUMAN,tr|A0A494C0Q7|A0A494C0Q7_HUMAN,tr|A0A494C1K3|A0A494C1K3_HUMAN" 3 1457.7263 1.5 115909 11597 3 1457.72877 486.916 General transcription factor II-I OS=Homo sapiens OX=9606 GN=GTF2I PE=1 SV=2 5.74 2240.1 - 1.90E+06 - - - 1.6999 - 3.057 0.553 - 490.5 1 2 1 0.0025 12 0 0 0 6.65E+07 4.45E+07 - - - 7.8021 0.9999 221125_WJC_METTL3_EV_vs_WT_F08.11598.11598.3 2.87E-07 20/60 K.IFVGGIKEDTEEHHLR.D "sp|Q32P51|RA1L2_HUMAN,sp|P09651|ROA1_HUMAN,sp|P22626|ROA2_HUMAN,tr|A0A7I2YQN4|A0A7I2YQN4_HUMAN,tr|A0A7I2YQX9|A0A7I2YQX9_HUMAN,tr|A0A7I2V4N0|A0A7I2V4N0_HUMAN,tr|A0A024RA28|A0A024RA28_HUMAN,tr|A0A7I2V4N1|A0A7I2V4N1_HUMAN,tr|A0A7I2V4I6|A0A7I2V4I6_HUMAN,tr|F8VZ49|F8VZ49_HUMAN,tr|A0A7I2V3R8|A0A7I2V3R8_HUMAN,tr|A0A087WUI2|A0A087WUI2_HUMAN,tr|A0A7I2V4S4|A0A7I2V4S4_HUMAN,tr|F8VTQ5|F8VTQ5_HUMAN,tr|F8W6I7|F8W6I7_HUMAN,tr|A0A7I2V2L6|A0A7I2V2L6_HUMAN,tr|A0A7I2V323|A0A7I2V323_HUMAN,tr|A0A7I2V3W0|A0A7I2V3W0_HUMAN,tr|A0A7I2V5U9|A0A7I2V5U9_HUMAN,tr|A0A2R8Y4L2|A0A2R8Y4L2_HUMAN,tr|A0A7I2V3P1|A0A7I2V3P1_HUMAN,tr|A0A7I2V3P7|A0A7I2V3P7_HUMAN" 22 1878.9588 1.24 115910 11598 3 1878.961779 627.3269 Heterogeneous nuclear ribonucleoprotein A1-like 2 OS=Homo sapiens OX=9606 GN=HNRNPA1L2 PE=2 SV=2 5.36 2240.2 - 711121 - - - 1.5796 - 3.458 0.603 - 530.2 1 2 1 0.003 16 0 0 0 2.14E+08 1.73E+08 - - - 8.4455 0.9999 221125_WJC_METTL3_EV_vs_WT_F08.11603.11603.3 4.86E-08 15/44 R.TNTPVK[136.11]EDWNVR[166.11].L "sp|P78347|GTF2I_HUMAN,tr|A0A494C0Q7|A0A494C0Q7_HUMAN,tr|A0A494C1K3|A0A494C1K3_HUMAN" 3 1475.7488 1.5 115913 11603 3 1475.750726 492.9235 General transcription factor II-I OS=Homo sapiens OX=9606 GN=GTF2I PE=1 SV=2 5.74 2240.9 - 2.06E+06 - - - 1.3308 - 2.858 0.574 - 448.1 1 2 1 0.002 12 0 0 0 6.65E+07 4.45E+07 - - - 7.8498 1 221125_WJC_METTL3_EV_vs_WT_F08.11605.11605.3 1.72E-07 15/72 K.AAAQLLQSQAQQSGAQQTK[136.11].K "sp|Q9NVA2|SEP11_HUMAN,tr|H0Y961|H0Y961_HUMAN,tr|H0Y9G8|H0Y9G8_HUMAN,tr|D6RGI3|D6RGI3_HUMAN,tr|D6RER5|D6RER5_HUMAN" 5 1964.0167 0.76 115915 11605 3 1964.017727 655.6795 Septin-11 OS=Homo sapiens OX=9606 GN=SEPTIN11 PE=1 SV=3 8.8 2241.1 - 516789 - - - 0.5397 - 3.32 0.519 - 291.6 1 2 0 0.0011 19 0 0 0 1.38E+07 1.82E+07 - - - 7.2741 1 221125_WJC_METTL3_EV_vs_WT_F08.11606.11606.3 3.54E-08 16/72 K.AAAQLLQSQAQQSGAQQTK.K "sp|Q9NVA2|SEP11_HUMAN,tr|H0Y961|H0Y961_HUMAN,tr|H0Y9G8|H0Y9G8_HUMAN,tr|D6RGI3|D6RGI3_HUMAN,tr|D6RER5|D6RER5_HUMAN" 5 1956.0025 0.76 115916 11606 3 1956.004044 653.0081 Septin-11 OS=Homo sapiens OX=9606 GN=SEPTIN11 PE=1 SV=3 8.8 2241.3 - 463737 - - - 0.8062 - 3.3 0.455 - 296.2 1 2 0 0.0016 19 0 0 0 1.38E+07 1.82E+07 - - - 6.5456 1 221125_WJC_METTL3_EV_vs_WT_F08.11616.11616.3 7.22E-09 19/56 L.FVGGIK[136.11]EDTEEHHLR[166.11].D "sp|Q32P51|RA1L2_HUMAN,sp|P09651|ROA1_HUMAN,sp|P22626|ROA2_HUMAN,tr|A0A7I2YQN4|A0A7I2YQN4_HUMAN,tr|A0A7I2YQX9|A0A7I2YQX9_HUMAN,tr|A0A7I2V4N0|A0A7I2V4N0_HUMAN,tr|A0A024RA28|A0A024RA28_HUMAN,tr|A0A7I2V4N1|A0A7I2V4N1_HUMAN,tr|A0A7I2V4I6|A0A7I2V4I6_HUMAN,tr|F8VZ49|F8VZ49_HUMAN,tr|A0A7I2V3R8|A0A7I2V3R8_HUMAN,tr|A0A087WUI2|A0A087WUI2_HUMAN,tr|A0A7I2V4S4|A0A7I2V4S4_HUMAN,tr|F8VTQ5|F8VTQ5_HUMAN,tr|F8W6I7|F8W6I7_HUMAN,tr|A0A7I2V2L6|A0A7I2V2L6_HUMAN,tr|A0A7I2V323|A0A7I2V323_HUMAN,tr|A0A7I2V3W0|A0A7I2V3W0_HUMAN,tr|A0A7I2V5U9|A0A7I2V5U9_HUMAN,tr|A0A2R8Y4L2|A0A2R8Y4L2_HUMAN,tr|A0A7I2V3P1|A0A7I2V3P1_HUMAN,tr|A0A7I2V3P7|A0A7I2V3P7_HUMAN" 22 1783.8972 2.25 115924 11616 3 1783.89704 595.6397 Heterogeneous nuclear ribonucleoprotein A1-like 2 OS=Homo sapiens OX=9606 GN=HNRNPA1L2 PE=2 SV=2 5.36 2242.5 - 614362 - - - -0.0992 - 3.462 0.611 - 470.5 1 1 1 -0.0002 15 0 0 0 5.12E+07 2.28E+07 - - - 8.5924 1 221125_WJC_METTL3_EV_vs_WT_F08.11617.11617.3 3.28E-08 26/52 F.VGGIKEDTEEHHLR.D "sp|Q32P51|RA1L2_HUMAN,sp|P09651|ROA1_HUMAN,sp|P22626|ROA2_HUMAN,tr|A0A7I2YQN4|A0A7I2YQN4_HUMAN,tr|A0A7I2YQX9|A0A7I2YQX9_HUMAN,tr|A0A7I2V4N0|A0A7I2V4N0_HUMAN,tr|A0A024RA28|A0A024RA28_HUMAN,tr|A0A7I2V4N1|A0A7I2V4N1_HUMAN,tr|A0A7I2V4I6|A0A7I2V4I6_HUMAN,tr|F8VZ49|F8VZ49_HUMAN,tr|A0A7I2V3R8|A0A7I2V3R8_HUMAN,tr|A0A087WUI2|A0A087WUI2_HUMAN,tr|A0A7I2V4S4|A0A7I2V4S4_HUMAN,tr|F8VTQ5|F8VTQ5_HUMAN,tr|F8W6I7|F8W6I7_HUMAN,tr|A0A7I2V2L6|A0A7I2V2L6_HUMAN,tr|A0A7I2V323|A0A7I2V323_HUMAN,tr|A0A7I2V3W0|A0A7I2V3W0_HUMAN,tr|A0A7I2V5U9|A0A7I2V5U9_HUMAN,tr|A0A2R8Y4L2|A0A2R8Y4L2_HUMAN,tr|A0A7I2V3P1|A0A7I2V3P1_HUMAN,tr|A0A7I2V3P7|A0A7I2V3P7_HUMAN" 22 1618.8063 1.51 115925 11617 3 1618.806584 540.6094 Heterogeneous nuclear ribonucleoprotein A1-like 2 OS=Homo sapiens OX=9606 GN=HNRNPA1L2 PE=2 SV=2 5.36 2242.6 - 516010 - - - 0.1551 - 4.485 0.663 - 1244.7 1 1 1 0.0003 14 0 0 0 2.80E+07 1.86E+07 - - - 9.92 0.9861 221125_WJC_METTL3_EV_vs_WT_F08.11618.11618.3 6.08E-06 22/48 V.GGIK[136.11]EDTEEHHLR[166.11].D "sp|Q32P51|RA1L2_HUMAN,sp|P09651|ROA1_HUMAN,sp|P22626|ROA2_HUMAN,tr|A0A7I2YQN4|A0A7I2YQN4_HUMAN,tr|A0A7I2YQX9|A0A7I2YQX9_HUMAN,tr|A0A7I2V4N0|A0A7I2V4N0_HUMAN,tr|A0A024RA28|A0A024RA28_HUMAN,tr|A0A7I2V4N1|A0A7I2V4N1_HUMAN,tr|A0A7I2V4I6|A0A7I2V4I6_HUMAN,tr|F8VZ49|F8VZ49_HUMAN,tr|A0A7I2V3R8|A0A7I2V3R8_HUMAN,tr|A0A087WUI2|A0A087WUI2_HUMAN,tr|A0A7I2V4S4|A0A7I2V4S4_HUMAN,tr|F8VTQ5|F8VTQ5_HUMAN,tr|F8W6I7|F8W6I7_HUMAN,tr|A0A7I2V2L6|A0A7I2V2L6_HUMAN,tr|A0A7I2V323|A0A7I2V323_HUMAN,tr|A0A7I2V3W0|A0A7I2V3W0_HUMAN,tr|A0A7I2V5U9|A0A7I2V5U9_HUMAN,tr|A0A2R8Y4L2|A0A2R8Y4L2_HUMAN,tr|A0A7I2V3P1|A0A7I2V3P1_HUMAN,tr|A0A7I2V3P7|A0A7I2V3P7_HUMAN" 22 1537.7604 1.3 115926 11618 3 1537.764512 513.5941 Heterogeneous nuclear ribonucleoprotein A1-like 2 OS=Homo sapiens OX=9606 GN=HNRNPA1L2 PE=2 SV=2 5.36 2242.7 - 389793 - - - 2.6812 - 3.766 0.563 - 637 1 1 1 0.0041 13 0 0 0 1.99E+07 1.53E+07 - - - 8.411 1 221125_WJC_METTL3_EV_vs_WT_F08.11619.11619.3 5.32E-10 22/48 V.GGIKEDTEEHHLR.D "sp|Q32P51|RA1L2_HUMAN,sp|P09651|ROA1_HUMAN,sp|P22626|ROA2_HUMAN,tr|A0A7I2YQN4|A0A7I2YQN4_HUMAN,tr|A0A7I2YQX9|A0A7I2YQX9_HUMAN,tr|A0A7I2V4N0|A0A7I2V4N0_HUMAN,tr|A0A024RA28|A0A024RA28_HUMAN,tr|A0A7I2V4N1|A0A7I2V4N1_HUMAN,tr|A0A7I2V4I6|A0A7I2V4I6_HUMAN,tr|F8VZ49|F8VZ49_HUMAN,tr|A0A7I2V3R8|A0A7I2V3R8_HUMAN,tr|A0A087WUI2|A0A087WUI2_HUMAN,tr|A0A7I2V4S4|A0A7I2V4S4_HUMAN,tr|F8VTQ5|F8VTQ5_HUMAN,tr|F8W6I7|F8W6I7_HUMAN,tr|A0A7I2V2L6|A0A7I2V2L6_HUMAN,tr|A0A7I2V323|A0A7I2V323_HUMAN,tr|A0A7I2V3W0|A0A7I2V3W0_HUMAN,tr|A0A7I2V5U9|A0A7I2V5U9_HUMAN,tr|A0A2R8Y4L2|A0A2R8Y4L2_HUMAN,tr|A0A7I2V3P1|A0A7I2V3P1_HUMAN,tr|A0A7I2V3P7|A0A7I2V3P7_HUMAN" 22 1519.7379 1.31 115927 11619 3 1519.736702 507.5866 Heterogeneous nuclear ribonucleoprotein A1-like 2 OS=Homo sapiens OX=9606 GN=HNRNPA1L2 PE=2 SV=2 5.36 2242.9 - 331025 - - - -0.8008 - 3.878 0.641 - 696.9 1 1 1 -0.0012 13 0 0 0 1.99E+07 1.52E+07 - - - 9.3608 0.9989 221125_WJC_METTL3_EV_vs_WT_F08.11626.11626.3 1.10E-14 30/116 N.VGAGGPAPAAGAAPAGGPAPSTAAAPAEEK.K sp|P05386|RLA1_HUMAN 1 2468.2296 2.36 115932 11626 3 2468.231277 823.7505 60S acidic ribosomal protein P1 OS=Homo sapiens OX=9606 GN=RPLP1 PE=1 SV=1 4.53 2243.6 - 609668 - - - 0.6932 - 4.517 0.553 - 718.7 1 1 0 0.0017 30 0 0 0 1.07E+07 4.52E+06 - - - 8.1739 0.9967 221125_WJC_METTL3_EV_vs_WT_F08.11627.11627.3 3.85E-10 20/116 N.VGAGGPAPAAGAAPAGGPAPSTAAAPAEEK[136.11].K sp|P05386|RLA1_HUMAN 1 2476.2438 2.36 115933 11627 3 2476.241444 826.4219 60S acidic ribosomal protein P1 OS=Homo sapiens OX=9606 GN=RPLP1 PE=1 SV=1 4.53 2243.8 - 379566 - - - -0.9377 - 3.491 0.451 - 241.5 1 1 0 -0.0023 30 0 0 0 1.07E+07 4.52E+06 - - - 6.4438 0.9887 221125_WJC_METTL3_EV_vs_WT_F08.11632.11632.4 6.54E-06 22/84 L.FVGGIK[136.11]EDTEEHHLR[166.11].D "sp|Q32P51|RA1L2_HUMAN,sp|P09651|ROA1_HUMAN,sp|P22626|ROA2_HUMAN,tr|A0A7I2YQN4|A0A7I2YQN4_HUMAN,tr|A0A7I2YQX9|A0A7I2YQX9_HUMAN,tr|A0A7I2V4N0|A0A7I2V4N0_HUMAN,tr|A0A024RA28|A0A024RA28_HUMAN,tr|A0A7I2V4N1|A0A7I2V4N1_HUMAN,tr|A0A7I2V4I6|A0A7I2V4I6_HUMAN,tr|F8VZ49|F8VZ49_HUMAN,tr|A0A7I2V3R8|A0A7I2V3R8_HUMAN,tr|A0A087WUI2|A0A087WUI2_HUMAN,tr|A0A7I2V4S4|A0A7I2V4S4_HUMAN,tr|F8VTQ5|F8VTQ5_HUMAN,tr|F8W6I7|F8W6I7_HUMAN,tr|A0A7I2V2L6|A0A7I2V2L6_HUMAN,tr|A0A7I2V323|A0A7I2V323_HUMAN,tr|A0A7I2V3W0|A0A7I2V3W0_HUMAN,tr|A0A7I2V5U9|A0A7I2V5U9_HUMAN,tr|A0A2R8Y4L2|A0A2R8Y4L2_HUMAN,tr|A0A7I2V3P1|A0A7I2V3P1_HUMAN,tr|A0A7I2V3P7|A0A7I2V3P7_HUMAN" 22 1783.8972 1.74 115936 11632 4 1783.895972 446.9816 Heterogeneous nuclear ribonucleoprotein A1-like 2 OS=Homo sapiens OX=9606 GN=HNRNPA1L2 PE=2 SV=2 5.36 2244.4 - 1.09E+06 - - - -0.6979 - 3.675 0.523 - 503.7 1 1 1 -0.0012 15 0 0 0 2.16E+07 1.24E+07 - - - 4.2436 0.9475 221125_WJC_METTL3_EV_vs_WT_F08.11639.11639.2 0.146 14/24 V.GGIKEDTEEHHLR.D "sp|Q32P51|RA1L2_HUMAN,sp|P09651|ROA1_HUMAN,sp|P22626|ROA2_HUMAN,tr|A0A7I2YQN4|A0A7I2YQN4_HUMAN,tr|A0A7I2YQX9|A0A7I2YQX9_HUMAN,tr|A0A7I2V4N0|A0A7I2V4N0_HUMAN,tr|A0A024RA28|A0A024RA28_HUMAN,tr|A0A7I2V4N1|A0A7I2V4N1_HUMAN,tr|A0A7I2V4I6|A0A7I2V4I6_HUMAN,tr|F8VZ49|F8VZ49_HUMAN,tr|A0A7I2V3R8|A0A7I2V3R8_HUMAN,tr|A0A087WUI2|A0A087WUI2_HUMAN,tr|A0A7I2V4S4|A0A7I2V4S4_HUMAN,tr|F8VTQ5|F8VTQ5_HUMAN,tr|F8W6I7|F8W6I7_HUMAN,tr|A0A7I2V2L6|A0A7I2V2L6_HUMAN,tr|A0A7I2V323|A0A7I2V323_HUMAN,tr|A0A7I2V3W0|A0A7I2V3W0_HUMAN,tr|A0A7I2V5U9|A0A7I2V5U9_HUMAN,tr|A0A2R8Y4L2|A0A2R8Y4L2_HUMAN,tr|A0A7I2V3P1|A0A7I2V3P1_HUMAN,tr|A0A7I2V3P7|A0A7I2V3P7_HUMAN" 22 1519.7379 1.32 115943 11639 2 1519.737923 760.8762 Heterogeneous nuclear ribonucleoprotein A1-like 2 OS=Homo sapiens OX=9606 GN=HNRNPA1L2 PE=2 SV=2 5.36 2245.2 - 175415 - - - 0.0026 - 2.802 0.542 - 446.3 1 1 1 0 13 0 0 0 2.53E+06 1.91E+06 - - - 5.6886 1 221125_WJC_METTL3_EV_vs_WT_F08.11644.11644.3 4.07E-11 27/52 F.VGGIK[136.11]EDTEEHHLR[166.11].D "sp|Q32P51|RA1L2_HUMAN,sp|P09651|ROA1_HUMAN,sp|P22626|ROA2_HUMAN,tr|A0A7I2YQN4|A0A7I2YQN4_HUMAN,tr|A0A7I2YQX9|A0A7I2YQX9_HUMAN,tr|A0A7I2V4N0|A0A7I2V4N0_HUMAN,tr|A0A024RA28|A0A024RA28_HUMAN,tr|A0A7I2V4N1|A0A7I2V4N1_HUMAN,tr|A0A7I2V4I6|A0A7I2V4I6_HUMAN,tr|F8VZ49|F8VZ49_HUMAN,tr|A0A7I2V3R8|A0A7I2V3R8_HUMAN,tr|A0A087WUI2|A0A087WUI2_HUMAN,tr|A0A7I2V4S4|A0A7I2V4S4_HUMAN,tr|F8VTQ5|F8VTQ5_HUMAN,tr|F8W6I7|F8W6I7_HUMAN,tr|A0A7I2V2L6|A0A7I2V2L6_HUMAN,tr|A0A7I2V323|A0A7I2V323_HUMAN,tr|A0A7I2V3W0|A0A7I2V3W0_HUMAN,tr|A0A7I2V5U9|A0A7I2V5U9_HUMAN,tr|A0A2R8Y4L2|A0A2R8Y4L2_HUMAN,tr|A0A7I2V3P1|A0A7I2V3P1_HUMAN,tr|A0A7I2V3P7|A0A7I2V3P7_HUMAN" 22 1636.8288 1.5 115946 11644 3 1636.833347 546.6169 Heterogeneous nuclear ribonucleoprotein A1-like 2 OS=Homo sapiens OX=9606 GN=HNRNPA1L2 PE=2 SV=2 5.36 2245.8 - 1.43E+06 - - - 2.7761 - 4.666 0.656 - 1386.6 1 1 1 0.0045 14 0 0 0 2.77E+07 1.85E+07 - - - 9.9459 1 221125_WJC_METTL3_EV_vs_WT_F08.11645.11645.3 2.86E-07 16/56 K.EQSGTIYLQHADEER.E "sp|P37198|NUP62_HUMAN,tr|M0QXN5|M0QXN5_HUMAN" 2 1774.8122 1.87 115947 11645 3 1774.812426 592.6113 Nuclear pore glycoprotein p62 OS=Homo sapiens OX=9606 GN=NUP62 PE=1 SV=3 4.4 2245.9 - 1.13E+06 - - - 0.124 - 3.207 0.55 - 474.5 1 2 0 0.0002 15 0 0 0 1.98E+07 1.06E+07 - - - 7.7127 0.9987 221125_WJC_METTL3_EV_vs_WT_F08.11655.11655.3 4.00E-05 14/44 R.DR[166.11]INNSLSELR[166.11]R[166.11].L "sp|Q9UBP5|HEY2_HUMAN,sp|Q9Y5J3|HEY1_HUMAN,tr|E5RHK6|E5RHK6_HUMAN,tr|A0A6I8PRS3|A0A6I8PRS3_HUMAN,tr|A0A6I8PRC2|A0A6I8PRC2_HUMAN,tr|A0A6I8PIY0|A0A6I8PIY0_HUMAN,tr|Q5TF93|Q5TF93_HUMAN" 7 1501.8103 1.3 115955 11655 3 1501.810133 501.6107 Hairy\enhancer-of-split related with YRPW motif protein 2 OS=Homo sapiens OX=9606 GN=HEY2 PE=1 SV=1 9.51 2247.1 - 604473 - - - -0.1432 - 2.49 0.286 - 192.9 1 2 1 -0.0002 12 0 0 0 1.14E+07 8.74E+06 - - - 4.2573 0.9331 221125_WJC_METTL3_EV_vs_WT_F08.11661.11661.4 0.00493 Oct-78 F.VGGIKEDTEEHHLR.D "sp|Q32P51|RA1L2_HUMAN,sp|P09651|ROA1_HUMAN,sp|P22626|ROA2_HUMAN,tr|A0A7I2YQN4|A0A7I2YQN4_HUMAN,tr|A0A7I2YQX9|A0A7I2YQX9_HUMAN,tr|A0A7I2V4N0|A0A7I2V4N0_HUMAN,tr|A0A024RA28|A0A024RA28_HUMAN,tr|A0A7I2V4N1|A0A7I2V4N1_HUMAN,tr|A0A7I2V4I6|A0A7I2V4I6_HUMAN,tr|F8VZ49|F8VZ49_HUMAN,tr|A0A7I2V3R8|A0A7I2V3R8_HUMAN,tr|A0A087WUI2|A0A087WUI2_HUMAN,tr|A0A7I2V4S4|A0A7I2V4S4_HUMAN,tr|F8VTQ5|F8VTQ5_HUMAN,tr|F8W6I7|F8W6I7_HUMAN,tr|A0A7I2V2L6|A0A7I2V2L6_HUMAN,tr|A0A7I2V323|A0A7I2V323_HUMAN,tr|A0A7I2V3W0|A0A7I2V3W0_HUMAN,tr|A0A7I2V5U9|A0A7I2V5U9_HUMAN,tr|A0A2R8Y4L2|A0A2R8Y4L2_HUMAN,tr|A0A7I2V3P1|A0A7I2V3P1_HUMAN,tr|A0A7I2V3P7|A0A7I2V3P7_HUMAN" 22 1618.8063 2.23 115959 11661 4 1618.806255 405.7089 Heterogeneous nuclear ribonucleoprotein A1-like 2 OS=Homo sapiens OX=9606 GN=HNRNPA1L2 PE=2 SV=2 5.36 2247.9 - 250323 - - - -0.0482 - 2.202 0.396 - 61.3 1 1 1 -0.0001 14 0 0 0 5.24E+06 2.35E+06 - - - 2.96 0.9928 221125_WJC_METTL3_EV_vs_WT_F08.11664.11664.3 0.000621 Oct-44 K.HKLDVTSVEDYK.A "sp|P48643|TCPE_HUMAN,tr|E9PCA1|E9PCA1_HUMAN,tr|B7ZAR1|B7ZAR1_HUMAN,tr|E7ENZ3|E7ENZ3_HUMAN" 4 1432.7198 0.61 115962 11664 3 1432.715568 478.5805 T-complex protein 1 subunit epsilon OS=Homo sapiens OX=9606 GN=CCT5 PE=1 SV=1 5.38 2248.3 - 473395 - - - -2.9601 - 2.23 0.284 - 175.2 1 2 1 -0.0042 12 0 0 0 5.41E+08 8.86E+08 - - - 3.9282 1 221125_WJC_METTL3_EV_vs_WT_F08.11668.11668.3 8.28E-12 16/60 K.RLDEEEEDNEGGEWER.V sp|Q99613|EIF3C_HUMAN 1 1990.8141 1.26 115964 11668 3 1990.815177 664.612 Eukaryotic translation initiation factor 3 subunit C OS=Homo sapiens OX=9606 GN=EIF3C PE=1 SV=1 3.89 2248.9 - 319913 - - - 0.5626 - 3.009 0.716 - 407.3 1 2 0 0.0011 16 0 0 0 9.99E+06 7.95E+06 - - - 9.349 0.9998 221125_WJC_METTL3_EV_vs_WT_F08.11669.11669.4 1.75E-05 Nov-72 K.KIHEEFSEHALLR.K "sp|Q9Y2L1|RRP44_HUMAN,tr|G3V1J5|G3V1J5_HUMAN" 2 1607.842 2.21 115965 11669 4 1607.841669 402.9678 Exosome complex exonuclease RRP44 OS=Homo sapiens OX=9606 GN=DIS3 PE=1 SV=2 6.02 2249 - 257036 - - - -0.1996 - 2.08 0.375 - 94.9 1 2 0 -0.0003 13 0 0 0 1.60E+07 7.24E+06 - - - 2.7615 0.9966 221125_WJC_METTL3_EV_vs_WT_F08.11676.11676.3 6.00E-05 16/56 F.SQPPAPPHQNTFPPR.S sp|Q96I24|FUBP3_HUMAN 1 1669.8325 7.58 115970 11676 3 1669.831961 557.6181 Far upstream element-binding protein 3 OS=Homo sapiens OX=9606 GN=FUBP3 PE=1 SV=2 9.49 2249.8 - 391031 - - - -0.3156 - 2.955 0.451 - 340.3 1 1 0 -0.0005 15 0 0 0 1.25E+07 1.64E+06 - - - 6.3953 0.9999 221125_WJC_METTL3_EV_vs_WT_F08.11677.11677.3 8.83E-07 13/44 K.HK[136.11]LDVTSVEDYK[136.11].A "sp|P48643|TCPE_HUMAN,tr|E9PCA1|E9PCA1_HUMAN,tr|B7ZAR1|B7ZAR1_HUMAN,tr|E7ENZ3|E7ENZ3_HUMAN" 4 1448.7482 0.61 115971 11677 3 1448.749469 483.9233 T-complex protein 1 subunit epsilon OS=Homo sapiens OX=9606 GN=CCT5 PE=1 SV=1 5.38 2249.9 - 4.60E+06 - - - 0.8697 - 2.647 0.488 - 277.3 1 2 1 0.0013 12 0 0 0 5.42E+08 8.87E+08 - - - 6.6786 0.9953 221125_WJC_METTL3_EV_vs_WT_F08.11678.11678.3 0.00627 15/44 R.DRINNSLSELRR.L "sp|Q9UBP5|HEY2_HUMAN,sp|Q9Y5J3|HEY1_HUMAN,tr|E5RHK6|E5RHK6_HUMAN,tr|A0A6I8PRS3|A0A6I8PRS3_HUMAN,tr|A0A6I8PRC2|A0A6I8PRC2_HUMAN,tr|A0A6I8PIY0|A0A6I8PIY0_HUMAN,tr|Q5TF93|Q5TF93_HUMAN" 7 1471.7855 1.26 115972 11678 3 1471.787827 491.6025 Hairy\enhancer-of-split related with YRPW motif protein 2 OS=Homo sapiens OX=9606 GN=HEY2 PE=1 SV=1 9.51 2250 - 1.20E+06 - - - 1.5553 - 1.846 0.299 - 181.4 1 2 1 0.0023 12 0 0 0 1.14E+07 9.04E+06 - - - 3.5721 0.9999 221125_WJC_METTL3_EV_vs_WT_F08.11690.11690.2 1.15E-07 28-Dec R.EATSSTSNFSSLSSK[136.11].F sp|Q9P2D1|CHD7_HUMAN 1 1539.7144 1.39 115983 11690 2 1539.714889 770.8645 Chromodomain-helicase-DNA-binding protein 7 OS=Homo sapiens OX=9606 GN=CHD7 PE=1 SV=3 6.1 2251.3 - 210413 - - - 0.3202 - 2.422 0.605 - 424.2 1 2 0 0.0005 15 0 0 0 7.88E+06 5.68E+06 - - - 5.6842 0.9999 221125_WJC_METTL3_EV_vs_WT_F08.11692.11692.4 0.000135 15/78 K.VLAQYYTVTDEHHR[166.11].S sp|Q9NX58|LYAR_HUMAN 1 1740.8459 1.89 115985 11692 4 1740.84714 436.2188 Cell growth-regulating nucleolar protein OS=Homo sapiens OX=9606 GN=LYAR PE=1 SV=2 5.99 2251.6 - 142512 - - - 0.7106 - 2.302 0.46 - 166.1 1 2 0 0.0012 14 0 0 0 4.28E+06 2.27E+06 - - - 3.5329 1 221125_WJC_METTL3_EV_vs_WT_F08.11696.11696.3 1.19E-06 17/60 K.R[166.11]LDEEEEDNEGGEWER[166.11].V sp|Q99613|EIF3C_HUMAN 1 2010.8306 1.26 115987 11696 3 2010.832877 671.2841 Eukaryotic translation initiation factor 3 subunit C OS=Homo sapiens OX=9606 GN=EIF3C PE=1 SV=1 3.89 2252.1 - 691157 - - - 1.1339 - 3.276 0.66 - 499.5 1 2 0 0.0023 16 0 0 0 9.99E+06 7.95E+06 - - - 8.9424 1 221125_WJC_METTL3_EV_vs_WT_F08.11697.11697.4 0.000199 14/72 K.K[136.11]IHEEFSEHALLR[166.11].K "sp|Q9Y2L1|RRP44_HUMAN,tr|G3V1J5|G3V1J5_HUMAN" 2 1625.8645 2.09 115988 11697 4 1625.865817 407.4734 Exosome complex exonuclease RRP44 OS=Homo sapiens OX=9606 GN=DIS3 PE=1 SV=2 6.02 2252.2 - 465626 - - - 0.8346 - 2.718 0.494 - 173.4 1 2 0 0.0014 13 0 0 0 1.43E+07 6.86E+06 - - - 3.8961 1 221125_WJC_METTL3_EV_vs_WT_F08.11698.11698.2 9.58E-07 18/22 K.HK[136.11]LDVTSVEDYK[136.11].A "sp|P48643|TCPE_HUMAN,tr|E9PCA1|E9PCA1_HUMAN,tr|B7ZAR1|B7ZAR1_HUMAN,tr|E7ENZ3|E7ENZ3_HUMAN" 4 1448.7482 0.59 115989 11698 2 1448.747608 725.3814 T-complex protein 1 subunit epsilon OS=Homo sapiens OX=9606 GN=CCT5 PE=1 SV=1 5.38 2252.4 - 1.02E+06 - - - -0.4148 - 3.532 0.645 - 909.9 1 2 1 -0.0006 12 0 0 0 2.90E+07 4.95E+07 - - - 7.125 0.9996 221125_WJC_METTL3_EV_vs_WT_F08.11701.11701.3 0.00174 Nov-48 K.NK[136.11]HEAMITDLEER[166.11].L sp|P35579|MYH9_HUMAN 1 1602.7791 0.94 115992 11701 3 1602.780731 535.267 Myosin-9 OS=Homo sapiens OX=9606 GN=MYH9 PE=1 SV=4 4.83 2252.7 - 493156 - - - 1.0326 - 2.372 0.41 - 230.8 1 2 1 0.0017 13 0 0 0 3.24E+07 3.45E+07 - - - 5.4525 1 221125_WJC_METTL3_EV_vs_WT_F08.11702.11702.3 3.49E-08 19/60 R.SSGPYGGGGQYFAKPR.N "sp|P09651|ROA1_HUMAN,tr|A0A7I2YQX9|A0A7I2YQX9_HUMAN,tr|A0A7I2V5N7|A0A7I2V5N7_HUMAN,tr|A0A7I2V661|A0A7I2V661_HUMAN,tr|A0A7I2V520|A0A7I2V520_HUMAN,tr|A0A7I2V2F1|A0A7I2V2F1_HUMAN,tr|A0A7I2V497|A0A7I2V497_HUMAN,tr|A0A7I2V3K5|A0A7I2V3K5_HUMAN,tr|A0A7I2V2M7|A0A7I2V2M7_HUMAN,tr|A0A7I2V4P7|A0A7I2V4P7_HUMAN,tr|A0A7I2V5P1|A0A7I2V5P1_HUMAN,tr|A0A7I2V334|A0A7I2V334_HUMAN,tr|A0A7I2V4E2|A0A7I2V4E2_HUMAN,tr|A0A7I2V4F8|A0A7I2V4F8_HUMAN,tr|A0A7I2V3R8|A0A7I2V3R8_HUMAN,tr|F8W6I7|F8W6I7_HUMAN,tr|A0A7I2V666|A0A7I2V666_HUMAN,tr|A0A7I2V2Q7|A0A7I2V2Q7_HUMAN,tr|A0A7I2V459|A0A7I2V459_HUMAN,tr|A0A7I2YQY2|A0A7I2YQY2_HUMAN,tr|H0YH80|H0YH80_HUMAN,tr|A0A7I2V3W0|A0A7I2V3W0_HUMAN,tr|A0A7I2V3U8|A0A7I2V3U8_HUMAN,tr|A0A7I2V2R4|A0A7I2V2R4_HUMAN,tr|A0A7I2V2X1|A0A7I2V2X1_HUMAN,tr|A0A7I2V453|A0A7I2V453_HUMAN,tr|A0A7I2V360|A0A7I2V360_HUMAN" 27 1627.7743 1.3 115993 11702 3 1627.774064 543.5987 Heterogeneous nuclear ribonucleoprotein A1 OS=Homo sapiens OX=9606 GN=HNRNPA1 PE=1 SV=5 9.7 2252.8 - 465691 - - - -0.1481 - 3.419 0.566 - 440.5 1 2 0 -0.0002 16 0 0 0 1.38E+08 1.07E+08 - - - 8.0046 1 221125_WJC_METTL3_EV_vs_WT_F08.11705.11705.2 2.27E-10 13/28 R.EATSSTSNFSSLSSK.F sp|Q9P2D1|CHD7_HUMAN 1 1531.7002 1.39 115996 11705 2 1531.698881 766.8574 Chromodomain-helicase-DNA-binding protein 7 OS=Homo sapiens OX=9606 GN=CHD7 PE=1 SV=3 6.1 2253.2 - 332867 - - - -0.8585 - 3.013 0.672 - 761.2 1 2 0 -0.0013 15 0 0 0 7.88E+06 5.68E+06 - - - 6.7156 0.9995 221125_WJC_METTL3_EV_vs_WT_F08.11706.11706.3 4.17E-05 Dec-76 K.TASVLSK[136.11]DDVAPESGDTTVK[136.11].K "sp|O76021|RL1D1_HUMAN,tr|J3QSV6|J3QSV6_HUMAN" 2 2035.0292 1.53 115997 11706 3 2035.034756 679.3503 Ribosomal L1 domain-containing protein 1 OS=Homo sapiens OX=9606 GN=RSL1D1 PE=1 SV=3 4.23 2253.3 - 287730 - - - 2.7326 - 2.327 0.516 - 164.9 1 2 1 0.0056 20 0 0 0 4.07E+06 2.66E+06 - - - 6.3403 0.9928 221125_WJC_METTL3_EV_vs_WT_F08.11709.11709.4 0.0372 Dec-84 R.LTWHAYPEDAENK[136.11]EK[136.11].E sp|P45973|CBX5_HUMAN 1 1845.8868 0.97 115998 11709 4 1845.88676 462.479 Chromobox protein homolog 5 OS=Homo sapiens OX=9606 GN=CBX5 PE=1 SV=1 4.83 2253.7 - 986774 - - - -0.0368 - 2.004 0.268 - 75.5 1 2 1 -0.0001 15 0 0 0 2.85E+07 2.93E+07 - - - 1.8074 0.9996 221125_WJC_METTL3_EV_vs_WT_F08.11710.11710.3 0.000276 Nov-48 K.NKHEAMITDLEER.L sp|P35579|MYH9_HUMAN 1 1584.7566 0.93 115999 11710 3 1584.75724 529.2595 Myosin-9 OS=Homo sapiens OX=9606 GN=MYH9 PE=1 SV=4 4.83 2253.8 - 532072 - - - 0.4001 - 2.371 0.397 - 226.8 1 2 1 0.0006 13 0 0 0 3.05E+07 3.26E+07 - - - 5.3067 0.9931 221125_WJC_METTL3_EV_vs_WT_F08.11713.11713.3 0.000614 14/76 K.TASVLSKDDVAPESGDTTVK.K "sp|O76021|RL1D1_HUMAN,tr|J3QSV6|J3QSV6_HUMAN" 2 2019.0008 1.53 116002 11713 3 2019.009057 674.0075 Ribosomal L1 domain-containing protein 1 OS=Homo sapiens OX=9606 GN=RSL1D1 PE=1 SV=3 4.23 2254.2 - 255165 - - - 4.0921 - 2.472 0.353 - 219.5 1 2 1 0.0083 20 0 0 0 3.79E+06 2.48E+06 - - - 4.6689 0.9997 221125_WJC_METTL3_EV_vs_WT_F08.11720.11720.3 5.32E-05 13/44 K.HKLDVTSVEDYK[136.11].A "sp|P48643|TCPE_HUMAN,tr|E9PCA1|E9PCA1_HUMAN,tr|B7ZAR1|B7ZAR1_HUMAN,tr|E7ENZ3|E7ENZ3_HUMAN" 4 1440.734 - 116007 11720 3 1440.735428 481.2519 T-complex protein 1 subunit epsilon OS=Homo sapiens OX=9606 GN=CCT5 PE=1 SV=1 5.38 2255.1 - 1.19E+06 - - - 0.9849 - 2.555 0.422 - 242.4 1 2 1 0.0014 12 0 0 0 - - - - - 5.8446 0.9996 221125_WJC_METTL3_EV_vs_WT_F08.11721.11721.3 0.000198 Dec-64 K.ERVPDSPSPAPSLEEGR.R sp|Q9UI36|DACH1_HUMAN 1 1821.8857 1.43 116008 11721 3 1821.888844 608.3025 Dachshund homolog 1 OS=Homo sapiens OX=9606 GN=DACH1 PE=1 SV=4 4.41 2255.2 - 573295 - - - 1.7224 - 2.637 0.437 - 140 1 2 1 0.0031 17 0 0 0 1.24E+07 8.71E+06 - - - 5.8609 0.9998 221125_WJC_METTL3_EV_vs_WT_F08.11725.11725.2 1.71E-06 22-Nov K.GSFSDTGLGDGK[136.11].M "sp|Q9Y2W1|TR150_HUMAN,tr|A0A3B3ITZ9|A0A3B3ITZ9_HUMAN" 2 1147.5237 2.7 116012 11725 2 1147.526141 574.7691 Thyroid hormone receptor-associated protein 3 OS=Homo sapiens OX=9606 GN=THRAP3 PE=1 SV=2 4.21 2255.7 - 278982 - - - 2.1429 - 1.961 0.606 - 229 1 2 0 0.0025 12 0 0 0 1.70E+07 6.28E+06 - - - 5.2881 1 221125_WJC_METTL3_EV_vs_WT_F08.11731.11731.3 1.13E-05 19/92 K.GEAAPGPAPPAPEATPPPASAAGK.D "sp|Q9NSI2|SLX9_HUMAN,tr|C9JJU7|C9JJU7_HUMAN" 2 2108.0538 2.46 116016 11731 3 2108.053616 703.6919 Ribosome biogenesis protein SLX9 homolog OS=Homo sapiens OX=9606 GN=SLX9 PE=1 SV=2 4.53 2256.5 - 845047 - - - -0.1034 - 3.153 0.534 - 257.1 1 2 0 -0.0002 24 0 0 0 5.65E+08 2.30E+08 - - - 7.1607 0.9998 221125_WJC_METTL3_EV_vs_WT_F08.11733.11733.4 1.20E-05 14/78 R.SDHLIQTDTVNLHR[166.11].K sp|P51151|RAB9A_HUMAN 1 1657.8412 1.44 116018 11733 4 1657.839514 415.4676 Ras-related protein Rab-9A OS=Homo sapiens OX=9606 GN=RAB9A PE=1 SV=1 5.93 2256.7 - 413839 - - - -0.988 - 2.551 0.382 - 262.2 1 2 0 -0.0016 14 0 0 0 1.48E+07 1.03E+07 - - - 2.8913 0.9983 221125_WJC_METTL3_EV_vs_WT_F08.11735.11735.3 0.0342 Aug-52 R.KLDPGSEETQTLVR.E sp|P26641|EF1G_HUMAN 1 1571.8155 1.36 116020 11735 3 1571.816822 524.9458 Elongation factor 1-gamma OS=Homo sapiens OX=9606 GN=EEF1G PE=1 SV=3 4.68 2257 - 278569 - - - 0.8404 - 1.776 0.258 - 80 1 2 0 0.0013 14 0 0 0 1.80E+06 1.32E+06 - - - 2.9425 0.9929 221125_WJC_METTL3_EV_vs_WT_F08.11746.11746.2 0.255 12-Aug R.HLQLAIR[166.11].N "sp|P16104|H2AX_HUMAN,sp|Q9BTM1|H2AJ_HUMAN,sp|Q93077|H2A1C_HUMAN,sp|Q99878|H2A1J_HUMAN,sp|Q16777|H2A2C_HUMAN,sp|Q96QV6|H2A1A_HUMAN,sp|P0C0S5|H2AZ_HUMAN,sp|P04908|H2A1B_HUMAN,sp|P20671|H2A1D_HUMAN,sp|P0C0S8|H2A1_HUMAN,sp|Q6FI13|H2A2A_HUMAN,sp|Q96KK5|H2A1H_HUMAN,sp|Q71UI9|H2AV_HUMAN,sp|Q7L7L0|H2A3_HUMAN,tr|C9J386|C9J386_HUMAN,tr|A0A0U1RR32|A0A0U1RR32_HUMAN,tr|A0A0U1RRH7|A0A0U1RRH7_HUMAN,tr|A0A3B3IS11|A0A3B3IS11_HUMAN,tr|H0YFX9|H0YFX9_HUMAN,tr|C9J0D1|C9J0D1_HUMAN,tr|A0A494C189|A0A494C189_HUMAN" 21 859.5267 1.33 116029 11746 2 859.527184 430.7706 Histone H2AX OS=Homo sapiens OX=9606 GN=H2AX PE=1 SV=2 9.76 2258.3 - 513674 - - - 0.5154 - 1.516 0.076 - 258.1 1 2 0 0.0004 7 0 0 0 8.21E+06 6.17E+06 - - - 0.9206 0.9982 221125_WJC_METTL3_EV_vs_WT_F08.11748.11748.4 0.0717 Dec-72 K.NKHEAMITDLEER.L sp|P35579|MYH9_HUMAN 1 1584.7566 0.79 116031 11748 4 1584.756154 397.1964 Myosin-9 OS=Homo sapiens OX=9606 GN=MYH9 PE=1 SV=4 4.83 2258.6 - 466630 - - - -0.2852 - 1.994 0.336 - 144.7 1 2 1 -0.0005 13 0 0 0 6.40E+06 8.06E+06 - - - 2.4063 0.9999 221125_WJC_METTL3_EV_vs_WT_F08.11751.11751.3 0.000116 Sep-60 R.SITDQVSDSSPYHSPK[136.11].V sp|P55771|PAX9_HUMAN 1 1754.8203 2.58 116034 11751 3 1754.818512 585.9474 Paired box protein Pax-9 OS=Homo sapiens OX=9606 GN=PAX9 PE=1 SV=3 5.19 2259 - 278811 - - - -0.995 - 1.715 0.454 - 57.7 1 2 0 -0.0017 16 0 0 0 1.21E+07 4.70E+06 - - - 4.9852 1 221125_WJC_METTL3_EV_vs_WT_F08.11758.11758.3 7.72E-08 13/52 K.DAHSQGEVVSC[160.03]LEK[136.11].G "sp|Q92896|GSLG1_HUMAN,tr|H3BQT1|H3BQT1_HUMAN,tr|H3BM42|H3BM42_HUMAN" 3 1565.7235 1.15 116039 11758 3 1565.726958 522.9151 Golgi apparatus protein 1 OS=Homo sapiens OX=9606 GN=GLG1 PE=1 SV=2 4.65 2259.8 - 590001 - - - 2.1952 - 2.923 0.545 - 285.1 1 2 0 0.0034 14 0 0 0 2.01E+07 1.74E+07 - - - 7.4658 0.9998 221125_WJC_METTL3_EV_vs_WT_F08.11759.11759.4 0.000103 16/72 K.NK[136.11]HEAMITDLEER[166.11].L sp|P35579|MYH9_HUMAN 1 1602.7791 1.02 116040 11759 4 1602.777785 401.702 Myosin-9 OS=Homo sapiens OX=9606 GN=MYH9 PE=1 SV=4 4.83 2260 - 537720 - - - -0.8055 - 2.771 0.464 - 286.6 1 2 1 -0.0013 13 0 0 0 6.31E+06 6.16E+06 - - - 3.6422 0.8546 221125_WJC_METTL3_EV_vs_WT_F08.11760.11760.3 0.0383 Sep-60 K.QAQTQTSPEHLVLQQK.Q "sp|Q9ULV3|CIZ1_HUMAN,tr|Q5SYW2|Q5SYW2_HUMAN,tr|F5H2X7|F5H2X7_HUMAN,tr|H0Y5D5|H0Y5D5_HUMAN,tr|A0A494C0L7|A0A494C0L7_HUMAN,tr|Q9BTG3|Q9BTG3_HUMAN" 6 1834.9537 4.33 116041 11760 3 1834.965563 612.6585 Cip1-interacting zinc finger protein OS=Homo sapiens OX=9606 GN=CIZ1 PE=1 SV=2 6.75 2260.1 - 402948 - - - 6.4508 - 1.766 0.227 - 64.4 2 2 0 0.0118 16 0 0 0 3.45E+07 7.96E+06 - - - 2.3875 1 221125_WJC_METTL3_EV_vs_WT_F08.11761.11761.3 3.98E-10 20/72 K.ASQEPSPK[136.11]PGTEVIPAAPR[166.11].K "sp|Q96CP2|FWCH2_HUMAN,tr|I3L1Y9|I3L1Y9_HUMAN,tr|I3L4I0|I3L4I0_HUMAN" 3 1949.0337 0.07 116042 11761 3 1949.03236 650.6852 FLYWCH family member 2 OS=Homo sapiens OX=9606 GN=FLYWCH2 PE=1 SV=1 6.19 2260.2 - 389775 - - - -0.6927 - 3.259 0.592 - 406 1 2 0 -0.0014 19 0 0 0 1.32E+06 1.76E+07 - - - 8.0424 0.9976 221125_WJC_METTL3_EV_vs_WT_F08.11763.11763.2 9.41E-06 26-Aug K.K[136.11]GPGEVAGTVTGQK[136.11].R "sp|Q86U44|MTA70_HUMAN,tr|F5H6D8|F5H6D8_HUMAN,tr|H0YFV6|H0YFV6_HUMAN,tr|B4DTN4|B4DTN4_HUMAN" 4 1343.738 0.001 116044 11763 2 1343.744446 672.8763 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 8.59 2260.5 - 182139 - - - 4.8127 - 2.025 0.518 - 188.9 1 2 0 0.0065 14 0 0 0 0.00E+00 2.77E+06 - - - 4.6355 1 221125_WJC_METTL3_EV_vs_WT_F08.11768.11768.3 2.54E-09 15/52 R.NNDVWQNHEAVPGR.A "sp|O00461|GOLI4_HUMAN,tr|F8W785|F8W785_HUMAN" 2 1634.755 11.41 116047 11768 3 1634.757097 545.9256 Golgi integral membrane protein 4 OS=Homo sapiens OX=9606 GN=GOLIM4 PE=1 SV=1 5.32 2261.1 - 1.15E+06 - - - 1.3036 - 2.981 0.461 - 405.5 1 2 0 0.0021 14 0 0 0 1.65E+07 1.45E+06 - - - 6.5818 1 221125_WJC_METTL3_EV_vs_WT_F08.11769.11769.3 5.16E-09 15/52 K.DAHSQGEVVSC[160.03]LEK.G "sp|Q92896|GSLG1_HUMAN,tr|H3BQT1|H3BQT1_HUMAN,tr|H3BM42|H3BM42_HUMAN" 3 1557.7093 1.17 116048 11769 3 1557.712533 520.2437 Golgi apparatus protein 1 OS=Homo sapiens OX=9606 GN=GLG1 PE=1 SV=2 4.65 2261.2 - 1.06E+06 - - - 2.062 - 2.895 0.577 - 379.9 1 2 0 0.0032 14 0 0 0 2.01E+07 1.72E+07 - - - 7.797 1 221125_WJC_METTL3_EV_vs_WT_F08.11770.11770.3 7.81E-05 17/52 R.SDHLIQTDTVNLHR[166.11].K sp|P51151|RAB9A_HUMAN 1 1657.8412 0.12 116049 11770 3 1657.842862 553.621 Ras-related protein Rab-9A OS=Homo sapiens OX=9606 GN=RAB9A PE=1 SV=1 5.93 2261.3 - 919094 - - - 1.0315 - 2.906 0.47 - 373.9 1 2 0 0.0017 14 0 0 0 1.11E+06 8.92E+06 - - - 6.6146 0.9999 221125_WJC_METTL3_EV_vs_WT_F08.11771.11771.3 0.00171 15/60 R.SITDQVSDSSPYHSPK.V sp|P55771|PAX9_HUMAN 1 1746.8061 2.6 116050 11771 3 1746.80812 583.276 Paired box protein Pax-9 OS=Homo sapiens OX=9606 GN=PAX9 PE=1 SV=3 5.19 2261.4 - 761590 - - - 1.1804 - 2.478 0.461 - 162.7 1 2 0 0.0021 16 0 0 0 1.25E+07 4.80E+06 - - - 6.0075 1 221125_WJC_METTL3_EV_vs_WT_F08.11773.11773.3 3.89E-12 25/80 K.VLHEAEGHIVTC[160.03]ETNTGEVYR.G "sp|P62318|SMD3_HUMAN,tr|H3BT13|H3BT13_HUMAN" 2 2413.1332 1.51 116052 11773 3 2413.13617 805.385 Small nuclear ribonucleoprotein Sm D3 OS=Homo sapiens OX=9606 GN=SNRPD3 PE=1 SV=1 4.87 2261.7 - 528586 - - - 1.2212 - 4.245 0.677 - 680 1 2 0 0.0029 21 0 0 0 9.31E+08 6.15E+08 - - - 9.5532 1 221125_WJC_METTL3_EV_vs_WT_F08.11775.11775.3 1.55E-06 18/68 K.AVHEQLAALSQAPVNK[136.11]PK[136.11].K sp|Q15059|BRD3_HUMAN 1 1916.0814 0.47 116054 11775 3 1916.08475 639.7011 Bromodomain-containing protein 3 OS=Homo sapiens OX=9606 GN=BRD3 PE=1 SV=1 8.64 2261.9 - 468616 - - - 1.7244 - 3.176 0.582 - 418.6 1 2 0 0.0033 18 0 0 0 1.45E+06 3.11E+06 - - - 7.9054 1 221125_WJC_METTL3_EV_vs_WT_F08.11779.11779.3 0.0008 15/88 K.TLSSPSNRPSGETSVPPPPAVGR.M sp|Q8WWM7|ATX2L_HUMAN 1 2289.1713 2.82 116058 11779 3 2289.171269 764.0644 Ataxin-2-like protein OS=Homo sapiens OX=9606 GN=ATXN2L PE=1 SV=2 9.26 2262.4 - 303593 - - - -0.0236 - 2.777 0.501 - 178.8 1 2 0 -0.0001 23 0 0 0 1.02E+07 3.60E+06 - - - 6.5217 1 221125_WJC_METTL3_EV_vs_WT_F08.11780.11780.2 4.15E-09 13/32 K.QNQTTAISTPASSEISK.A sp|P49792|RBP2_HUMAN 1 1761.8745 1.07 116059 11780 2 1761.872423 881.9445 E3 SUMO-protein ligase RanBP2 OS=Homo sapiens OX=9606 GN=RANBP2 PE=1 SV=2 6 2262.6 - 140813 - - - -1.163 - 2.839 0.613 - 485.9 1 2 0 -0.002 17 0 0 0 2.50E+07 2.34E+07 - - - 6.1333 0.9999 221125_WJC_METTL3_EV_vs_WT_F08.11781.11781.2 1.59E-05 Aug-32 K.QNQTTAISTPASSEISK[136.11].A sp|P49792|RBP2_HUMAN 1 1769.8887 1.07 116060 11781 2 1769.889117 885.9516 E3 SUMO-protein ligase RanBP2 OS=Homo sapiens OX=9606 GN=RANBP2 PE=1 SV=2 6 2262.7 - 118744 - - - 0.2514 - 2.178 0.535 - 148.1 1 2 0 0.0004 17 0 0 0 2.50E+07 2.34E+07 - - - 4.9061 0.9998 221125_WJC_METTL3_EV_vs_WT_F08.11785.11785.4 2.61E-05 17/84 R.SLDPADERDDVLAKR.L "sp|Q8WXI9|P66B_HUMAN,tr|A0A0U1RR34|A0A0U1RR34_HUMAN,tr|A0A0U1RRM1|A0A0U1RRM1_HUMAN,tr|A0A0U1RRK3|A0A0U1RRK3_HUMAN" 4 1698.8537 1.45 116062 11785 4 1698.853364 425.7207 Transcriptional repressor p66-beta OS=Homo sapiens OX=9606 GN=GATAD2B PE=1 SV=1 4.36 2263.2 - 1.05E+06 - - - -0.1842 - 2.093 0.462 - 227.5 1 2 1 -0.0003 15 0 0 0 1.06E+07 7.28E+06 - - - 3.5114 0.9988 221125_WJC_METTL3_EV_vs_WT_F08.11786.11786.4 0.0238 18/84 R.SLDPADER[166.11]DDVLAK[136.11]R[166.11].L "sp|Q8WXI9|P66B_HUMAN,tr|A0A0U1RR34|A0A0U1RR34_HUMAN,tr|A0A0U1RRM1|A0A0U1RRM1_HUMAN,tr|A0A0U1RRK3|A0A0U1RRK3_HUMAN" 4 1726.8844 1.57 116063 11786 4 1726.883583 432.7284 Transcriptional repressor p66-beta OS=Homo sapiens OX=9606 GN=GATAD2B PE=1 SV=1 4.36 2263.4 - 596435 - - - -0.483 - 2.119 0.359 - 221.6 1 2 1 -0.0008 15 0 0 0 1.06E+07 6.71E+06 - - - 2.6192 1 221125_WJC_METTL3_EV_vs_WT_F08.11787.11787.3 0.00027 20/88 K.TLSSPSNR[166.11]PSGETSVPPPPAVGR[166.11].M sp|Q8WWM7|ATX2L_HUMAN 1 2309.1879 2.82 116064 11787 3 2309.190635 770.7366 Ataxin-2-like protein OS=Homo sapiens OX=9606 GN=ATXN2L PE=1 SV=2 9.26 2263.5 - 336203 - - - 1.2004 - 3.189 0.56 - 312.2 1 2 0 0.0028 23 0 0 0 1.02E+07 3.60E+06 - - - 7.5033 1 221125_WJC_METTL3_EV_vs_WT_F08.11788.11788.2 4.38E-08 20/46 K.GEAAPGPAPPAPEATPPPASAAGK.D "sp|Q9NSI2|SLX9_HUMAN,tr|C9JJU7|C9JJU7_HUMAN" 2 2108.0538 2.68 116065 11788 2 2108.053337 1055.0342 Ribosome biogenesis protein SLX9 homolog OS=Homo sapiens OX=9606 GN=SLX9 PE=1 SV=2 4.53 2263.6 - 324900 - - - -0.2358 - 3.601 0.65 - 585.9 1 2 0 -0.0005 24 0 0 0 6.72E+07 2.51E+07 - - - 6.9917 1 221125_WJC_METTL3_EV_vs_WT_F08.11789.11789.3 7.96E-07 13/68 R.TPAQSGAWDPNNPNTPSR.A sp|O00267|SPT5H_HUMAN 1 1908.8715 1.58 116066 11789 3 1908.872137 637.2978 Transcription elongation factor SPT5 OS=Homo sapiens OX=9606 GN=SUPT5H PE=1 SV=1 5.5 2263.8 - 316894 - - - 0.3589 - 2.627 0.485 - 157.9 1 2 0 0.0007 18 0 0 0 4.10E+06 2.60E+06 - - - 6.3521 0.9994 221125_WJC_METTL3_EV_vs_WT_F08.11791.11791.2 5.26E-06 26-Sep R.SSFYPDGGDQETAK.T "sp|Q9NYF8|BCLF1_HUMAN,tr|H0YF00|H0YF00_HUMAN,tr|E9PKI6|E9PKI6_HUMAN,tr|A0A1W2PQ43|A0A1W2PQ43_HUMAN,tr|E9PK91|E9PK91_HUMAN,tr|E9PJA7|E9PJA7_HUMAN,tr|E9PK09|E9PK09_HUMAN,tr|E9PQN2|E9PQN2_HUMAN" 8 1500.6369 2.35 116068 11791 2 1500.641225 751.3257 Bcl-2-associated transcription factor 1 OS=Homo sapiens OX=9606 GN=BCLAF1 PE=1 SV=2 4.03 2264 - 158961 - - - 2.9034 - 1.805 0.555 - 147.4 1 2 0 0.0044 14 0 0 0 2.57E+07 1.09E+07 - - - 4.6208 1 221125_WJC_METTL3_EV_vs_WT_F08.11796.11796.3 0.000192 19/60 K.NVTDVVNTC[160.03]HDAGISK[136.11].K sp|Q9Y3I0|RTCB_HUMAN 1 1736.8243 1.34 116071 11796 3 1736.824884 579.9487 RNA-splicing ligase RtcB homolog OS=Homo sapiens OX=9606 GN=RTCB PE=1 SV=1 5.21 2264.7 - 2.71E+06 - - - 0.3374 - 3.136 0.568 - 326.6 1 2 0 0.0006 16 0 0 0 1.15E+08 8.59E+07 - - - 7.8051 1 221125_WJC_METTL3_EV_vs_WT_F08.11797.11797.3 5.62E-07 13/44 R.TNAENEFVTIKK.D sp|P04264|K2C1_HUMAN 1 1392.7249 999 116072 11797 3 1392.724544 465.2489 "Keratin, type II cytoskeletal 1 OS=Homo sapiens OX=9606 GN=KRT1 PE=1 SV=6" 5.81 2264.8 - 2.15E+06 - - - -0.252 - 2.592 0.568 - 246.9 1 2 0 -0.0004 12 0 0 0 2.13E+08 0.00E+00 - - - 7.5125 0.9941 221125_WJC_METTL3_EV_vs_WT_F08.11798.11798.3 0.00027 22/76 A.SSLVSGLNSSASEPAK[136.11]EPAK[136.11].K "sp|Q86U44|MTA70_HUMAN,tr|F5H6D8|F5H6D8_HUMAN,tr|H0YFV6|H0YFV6_HUMAN,tr|B4DTN4|B4DTN4_HUMAN" 4 1974.024 0.001 116073 11798 3 1974.022479 659.0153 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 5.86 2264.8 - 2.08E+06 - - - -0.7958 - 3.728 0.55 - 472.8 1 1 1 -0.0016 20 0 0 0 0.00E+00 8.62E+07 - - - 7.8639 1 221125_WJC_METTL3_EV_vs_WT_F08.11800.11800.3 1.39E-08 28/84 R.LLEGEDAHLSSQQASGQSYSSR.E sp|P08779|K1C16_HUMAN 1 2349.0833 758.5 116075 11800 3 2349.084638 784.035 "Keratin, type I cytoskeletal 16 OS=Homo sapiens OX=9606 GN=KRT16 PE=1 SV=4" 4.65 2265 - 1.62E+06 - - - 0.5713 - 4.786 0.718 - 756.1 1 2 0 0.0013 22 0 0 0 7.98E+08 1.05E+06 - - - 10.2566 1 221125_WJC_METTL3_EV_vs_WT_F08.11801.11801.3 4.73E-06 14/48 R.SLENYHFVDEHGK.D sp|Q14677|EPN4_HUMAN 1 1573.7161 1.58 116076 11801 3 1573.716285 525.5793 Clathrin interactor 1 OS=Homo sapiens OX=9606 GN=CLINT1 PE=1 SV=1 5.26 2265.1 - 979079 - - - 0.1042 - 2.682 0.544 - 189.3 1 2 0 0.0002 13 0 0 0 3.88E+08 2.46E+08 - - - 7.2799 1 221125_WJC_METTL3_EV_vs_WT_F08.11803.11803.4 3.30E-05 15/72 R.SLENYHFVDEHGK[136.11].D sp|Q14677|EPN4_HUMAN 1 1581.7303 1.65 116078 11803 4 1581.731264 396.4399 Clathrin interactor 1 OS=Homo sapiens OX=9606 GN=CLINT1 PE=1 SV=1 5.26 2265.3 - 905081 - - - 0.5962 - 2.599 0.473 - 123.7 1 2 0 0.0009 13 0 0 0 4.41E+08 2.68E+08 - - - 3.6969 0.9996 221125_WJC_METTL3_EV_vs_WT_F08.11806.11806.4 7.47E-05 Dec-90 R.GGEVLDSSHDDIK[136.11]LEK[136.11].S sp|O76031|CLPX_HUMAN 1 1756.8814 1.43 116081 11806 4 1756.883359 440.2276 "ATP-dependent Clp protease ATP-binding subunit clpX-like, mitochondrial OS=Homo sapiens OX=9606 GN=CLPX PE=1 SV=2" 4.43 2265.7 - 275934 - - - 1.1105 - 1.837 0.427 - 110.6 1 2 1 0.0019 16 0 0 0 9.67E+06 6.78E+06 - - - 3.1563 1 221125_WJC_METTL3_EV_vs_WT_F08.11807.11807.2 3.87E-09 21/46 K.GEAAPGPAPPAPEATPPPASAAGK[136.11].D "sp|Q9NSI2|SLX9_HUMAN,tr|C9JJU7|C9JJU7_HUMAN" 2 2116.068 3.01 116082 11807 2 2116.072431 1059.0413 Ribosome biogenesis protein SLX9 homolog OS=Homo sapiens OX=9606 GN=SLX9 PE=1 SV=2 4.53 2265.9 - 262611 - - - 2.0779 - 3.353 0.625 - 703.1 1 2 0 0.0044 24 0 0 0 7.79E+07 2.59E+07 - - - 6.6304 1 221125_WJC_METTL3_EV_vs_WT_F08.11809.11809.2 3.72E-08 30-Dec R.SSGPYGGGGQYFAKPR.N "sp|P09651|ROA1_HUMAN,tr|A0A7I2YQX9|A0A7I2YQX9_HUMAN,tr|A0A7I2V5N7|A0A7I2V5N7_HUMAN,tr|A0A7I2V661|A0A7I2V661_HUMAN,tr|A0A7I2V520|A0A7I2V520_HUMAN,tr|A0A7I2V2F1|A0A7I2V2F1_HUMAN,tr|A0A7I2V497|A0A7I2V497_HUMAN,tr|A0A7I2V3K5|A0A7I2V3K5_HUMAN,tr|A0A7I2V2M7|A0A7I2V2M7_HUMAN,tr|A0A7I2V4P7|A0A7I2V4P7_HUMAN,tr|A0A7I2V5P1|A0A7I2V5P1_HUMAN,tr|A0A7I2V334|A0A7I2V334_HUMAN,tr|A0A7I2V4E2|A0A7I2V4E2_HUMAN,tr|A0A7I2V4F8|A0A7I2V4F8_HUMAN,tr|A0A7I2V3R8|A0A7I2V3R8_HUMAN,tr|F8W6I7|F8W6I7_HUMAN,tr|A0A7I2V666|A0A7I2V666_HUMAN,tr|A0A7I2V2Q7|A0A7I2V2Q7_HUMAN,tr|A0A7I2V459|A0A7I2V459_HUMAN,tr|A0A7I2YQY2|A0A7I2YQY2_HUMAN,tr|H0YH80|H0YH80_HUMAN,tr|A0A7I2V3W0|A0A7I2V3W0_HUMAN,tr|A0A7I2V3U8|A0A7I2V3U8_HUMAN,tr|A0A7I2V2R4|A0A7I2V2R4_HUMAN,tr|A0A7I2V2X1|A0A7I2V2X1_HUMAN,tr|A0A7I2V453|A0A7I2V453_HUMAN,tr|A0A7I2V360|A0A7I2V360_HUMAN" 27 1627.7743 1.7 116084 11809 2 1627.772633 814.8944 Heterogeneous nuclear ribonucleoprotein A1 OS=Homo sapiens OX=9606 GN=HNRNPA1 PE=1 SV=5 9.7 2266.1 - 178575 - - - -1.0272 - 2.502 0.647 - 452.4 1 2 0 -0.0017 16 0 0 0 3.15E+06 1.85E+06 - - - 6.0739 1 221125_WJC_METTL3_EV_vs_WT_F08.11810.11810.2 1.08E-11 16/30 K.NVTDVVNTC[160.03]HDAGISK.K sp|Q9Y3I0|RTCB_HUMAN 1 1728.8101 1.34 116085 11810 2 1728.808341 865.4123 RNA-splicing ligase RtcB homolog OS=Homo sapiens OX=9606 GN=RTCB PE=1 SV=1 5.21 2266.2 - 178362 - - - -1.0163 - 3.401 0.715 - 668.3 1 2 0 -0.0018 16 0 0 0 7.65E+06 5.72E+06 - - - 7.3309 1 221125_WJC_METTL3_EV_vs_WT_F08.11811.11811.2 1.99E-07 16/30 K.NVTDVVNTC[160.03]HDAGISK[136.11].K sp|Q9Y3I0|RTCB_HUMAN 1 1736.8243 1.34 116086 11811 2 1736.827007 869.4194 RNA-splicing ligase RtcB homolog OS=Homo sapiens OX=9606 GN=RTCB PE=1 SV=1 5.21 2266.4 - 148123 - - - 1.5597 - 3.367 0.637 - 654.4 1 2 0 0.0027 16 0 0 0 7.65E+06 5.72E+06 - - - 6.7298 1 221125_WJC_METTL3_EV_vs_WT_F08.11815.11815.4 4.13E-11 17/120 K.VLHEAEGHIVTC[160.03]ETNTGEVYR.G "sp|P62318|SMD3_HUMAN,tr|H3BT13|H3BT13_HUMAN" 2 2413.1332 1.74 116088 11815 4 2413.133617 604.2906 Small nuclear ribonucleoprotein Sm D3 OS=Homo sapiens OX=9606 GN=SNRPD3 PE=1 SV=1 4.87 2266.8 - 2.28E+07 - - - 0.1633 - 3.692 0.587 - 237 1 2 0 0.0004 21 0 0 0 1.06E+09 6.12E+08 - - - 4.767 0.9999 221125_WJC_METTL3_EV_vs_WT_F08.11816.11816.3 1.26E-07 18/52 K.K[136.11]SVEEGK[136.11]IDGIIDK[136.11].T sp|Q96A49|SYAP1_HUMAN 1 1553.8727 1.33 116089 11816 3 1553.871738 518.9648 Synapse-associated protein 1 OS=Homo sapiens OX=9606 GN=SYAP1 PE=1 SV=1 4.78 2266.9 - 5.08E+06 - - - -0.6114 - 3.305 0.519 - 337.1 1 2 1 -0.0009 14 0 0 0 2.63E+08 1.97E+08 - - - 7.503 1 221125_WJC_METTL3_EV_vs_WT_F08.11817.11817.3 1.09E-06 13/48 R.SLENYHFVDEHGK[136.11].D sp|Q14677|EPN4_HUMAN 1 1581.7303 1.58 116090 11817 3 1581.72886 528.2507 Clathrin interactor 1 OS=Homo sapiens OX=9606 GN=CLINT1 PE=1 SV=1 5.26 2266.9 - 4.86E+06 - - - -0.9237 - 2.175 0.535 - 138.3 1 2 0 -0.0015 13 0 0 0 3.88E+08 2.46E+08 - - - 6.6111 0.9994 221125_WJC_METTL3_EV_vs_WT_F08.11819.11819.4 0.000476 18/78 K.KSVEEGKIDGIIDK.T sp|Q96A49|SYAP1_HUMAN 1 1529.8301 1.36 116092 11819 4 1529.828408 383.4648 Synapse-associated protein 1 OS=Homo sapiens OX=9606 GN=SYAP1 PE=1 SV=1 4.78 2267.1 - 1.65E+06 - - - -1.0982 - 3.184 0.377 - 290.6 1 2 1 -0.0017 14 0 0 0 7.53E+07 5.53E+07 - - - 2.9284 0.9999 221125_WJC_METTL3_EV_vs_WT_F08.11820.11820.4 6.74E-06 13/84 K.LIHTEDPFNDEHQER.Q sp|Q6ZU65|UBN2_HUMAN 1 1878.8497 1.81 116093 11820 4 1878.849046 470.7197 Ubinuclein-2 OS=Homo sapiens OX=9606 GN=UBN2 PE=1 SV=2 4.49 2267.1 - 1.56E+06 - - - -0.3236 - 3.106 0.448 - 168.7 1 2 0 -0.0006 15 0 0 0 4.05E+07 2.23E+07 - - - 3.5307 0.9997 221125_WJC_METTL3_EV_vs_WT_F08.11821.11821.4 0.000157 16/78 K.K[136.11]SVEEGK[136.11]IDGIIDK[136.11].T sp|Q96A49|SYAP1_HUMAN 1 1553.8727 1.36 116094 11821 4 1553.870466 389.4754 Synapse-associated protein 1 OS=Homo sapiens OX=9606 GN=SYAP1 PE=1 SV=1 4.78 2267.2 - 1.35E+06 - - - -1.43 - 3.011 0.436 - 205 1 2 1 -0.0022 14 0 0 0 7.53E+07 5.53E+07 - - - 3.4215 1 221125_WJC_METTL3_EV_vs_WT_F08.11824.11824.2 8.78E-05 13/22 R.TNAENEFVTIKK.D sp|P04264|K2C1_HUMAN 1 1392.7249 999 116097 11824 2 1392.723215 697.3697 "Keratin, type II cytoskeletal 1 OS=Homo sapiens OX=9606 GN=KRT1 PE=1 SV=6" 5.81 2267.6 - 679903 - - - -1.2063 - 2.733 0.561 - 616.9 1 2 0 -0.0017 12 0 0 0 2.05E+07 0.00E+00 - - - 5.8294 1 221125_WJC_METTL3_EV_vs_WT_F08.11828.11828.2 4.34E-10 18/24 R.SLENYHFVDEHGK.D sp|Q14677|EPN4_HUMAN 1 1573.7161 1.92 116101 11828 2 1573.716614 787.8653 Clathrin interactor 1 OS=Homo sapiens OX=9606 GN=CLINT1 PE=1 SV=1 5.26 2268.1 - 204611 - - - 0.3133 - 3.687 0.623 - 1246.6 1 2 0 0.0005 13 0 0 0 2.23E+07 1.16E+07 - - - 6.9912 1 221125_WJC_METTL3_EV_vs_WT_F08.11830.11830.4 6.70E-06 14/72 R.SLENYHFVDEHGK.D sp|Q14677|EPN4_HUMAN 1 1573.7161 1.65 116102 11830 4 1573.714098 394.4363 Clathrin interactor 1 OS=Homo sapiens OX=9606 GN=CLINT1 PE=1 SV=1 5.26 2268.4 - 2.10E+07 - - - -1.2855 - 2.535 0.498 - 101 1 2 0 -0.002 13 0 0 0 4.41E+08 2.68E+08 - - - 3.9049 1 221125_WJC_METTL3_EV_vs_WT_F08.11832.11832.3 4.32E-08 22/52 K.KSVEEGKIDGIIDK.T sp|Q96A49|SYAP1_HUMAN 1 1529.8301 1.33 116103 11832 3 1529.828279 510.9506 Synapse-associated protein 1 OS=Homo sapiens OX=9606 GN=SYAP1 PE=1 SV=1 4.78 2268.6 - 1.39E+07 - - - -1.1825 - 3.652 0.59 - 556.7 1 2 1 -0.0018 14 0 0 0 2.63E+08 1.97E+08 - - - 8.5597 0.9998 221125_WJC_METTL3_EV_vs_WT_F08.11836.11836.3 0.000345 Dec-64 R.EIVHLQAGQC[160.03]GNQIGAK[136.11].F "sp|P04350|TBB4A_HUMAN,sp|Q9BVA1|TBB2B_HUMAN,sp|P07437|TBB5_HUMAN,sp|Q13509|TBB3_HUMAN,sp|Q13885|TBB2A_HUMAN,sp|P68371|TBB4B_HUMAN,tr|M0R2D3|M0R2D3_HUMAN,tr|G3V3W7|G3V3W7_HUMAN,tr|M0R2T4|M0R2T4_HUMAN,tr|G3V3R4|G3V3R4_HUMAN,tr|M0R042|M0R042_HUMAN,tr|M0QY85|M0QY85_HUMAN,tr|M0QZL7|M0QZL7_HUMAN,tr|G3V5W4|G3V5W4_HUMAN,tr|M0R0X0|M0R0X0_HUMAN,tr|M0QYM7|M0QYM7_HUMAN,tr|G3V4U2|G3V4U2_HUMAN,tr|M0R278|M0R278_HUMAN,tr|M0QY37|M0QY37_HUMAN,tr|G3V2R8|G3V2R8_HUMAN,tr|G3V3J6|G3V3J6_HUMAN,tr|M0QX14|M0QX14_HUMAN,tr|G3V2N6|G3V2N6_HUMAN" 23 1829.9298 0.57 116107 11836 3 1829.927109 610.9839 Tubulin beta-4A chain OS=Homo sapiens OX=9606 GN=TUBB4A PE=1 SV=2 6.83 2268.8 - 1.65E+06 - - - -1.452 - 2.069 0.379 - 152.3 1 2 0 -0.0027 17 0 0 0 2.99E+08 5.25E+08 - - - 4.6015 1 221125_WJC_METTL3_EV_vs_WT_F08.11837.11837.3 3.80E-06 14/56 K.LIHTEDPFNDEHQER.Q sp|Q6ZU65|UBN2_HUMAN 1 1878.8497 2.74 116108 11837 3 1878.848789 627.2905 Ubinuclein-2 OS=Homo sapiens OX=9606 GN=UBN2 PE=1 SV=2 4.49 2268.9 - 1.23E+06 - - - -0.4604 - 3.107 0.511 - 353.1 1 2 0 -0.0009 15 0 0 0 2.66E+07 9.74E+06 - - - 7.195 1 221125_WJC_METTL3_EV_vs_WT_F08.11839.11839.2 5.54E-07 22/26 K.KSVEEGKIDGIIDK.T sp|Q96A49|SYAP1_HUMAN 1 1529.8301 1.54 116110 11839 2 1529.830339 765.9223 Synapse-associated protein 1 OS=Homo sapiens OX=9606 GN=SYAP1 PE=1 SV=1 4.78 2269.1 - 526226 - - - 0.1641 - 4.322 0.629 - 1478.9 1 2 1 0.0003 14 0 0 0 1.20E+07 7.79E+06 - - - 7.3598 1 221125_WJC_METTL3_EV_vs_WT_F08.11840.11840.2 4.25E-10 18/24 R.SLENYHFVDEHGK[136.11].D sp|Q14677|EPN4_HUMAN 1 1581.7303 2.49 116111 11840 2 1581.728108 791.8724 Clathrin interactor 1 OS=Homo sapiens OX=9606 GN=CLINT1 PE=1 SV=1 5.26 2269.3 - 502946 - - - -1.3991 - 3.603 0.75 - 1468 1 2 0 -0.0022 13 0 0 0 2.90E+07 1.16E+07 - - - 7.8695 1 221125_WJC_METTL3_EV_vs_WT_F08.11842.11842.3 6.20E-11 20/60 R.SSGPYGGGGQYFAK[136.11]PR[166.11].N "sp|P09651|ROA1_HUMAN,tr|A0A7I2YQX9|A0A7I2YQX9_HUMAN,tr|A0A7I2V5N7|A0A7I2V5N7_HUMAN,tr|A0A7I2V661|A0A7I2V661_HUMAN,tr|A0A7I2V520|A0A7I2V520_HUMAN,tr|A0A7I2V2F1|A0A7I2V2F1_HUMAN,tr|A0A7I2V497|A0A7I2V497_HUMAN,tr|A0A7I2V3K5|A0A7I2V3K5_HUMAN,tr|A0A7I2V2M7|A0A7I2V2M7_HUMAN,tr|A0A7I2V4P7|A0A7I2V4P7_HUMAN,tr|A0A7I2V5P1|A0A7I2V5P1_HUMAN,tr|A0A7I2V334|A0A7I2V334_HUMAN,tr|A0A7I2V4E2|A0A7I2V4E2_HUMAN,tr|A0A7I2V4F8|A0A7I2V4F8_HUMAN,tr|A0A7I2V3R8|A0A7I2V3R8_HUMAN,tr|F8W6I7|F8W6I7_HUMAN,tr|A0A7I2V666|A0A7I2V666_HUMAN,tr|A0A7I2V2Q7|A0A7I2V2Q7_HUMAN,tr|A0A7I2V459|A0A7I2V459_HUMAN,tr|A0A7I2YQY2|A0A7I2YQY2_HUMAN,tr|H0YH80|H0YH80_HUMAN,tr|A0A7I2V3W0|A0A7I2V3W0_HUMAN,tr|A0A7I2V3U8|A0A7I2V3U8_HUMAN,tr|A0A7I2V2R4|A0A7I2V2R4_HUMAN,tr|A0A7I2V2X1|A0A7I2V2X1_HUMAN,tr|A0A7I2V453|A0A7I2V453_HUMAN,tr|A0A7I2V360|A0A7I2V360_HUMAN" 27 1645.7968 1.31 116112 11842 3 1645.795724 549.6062 Heterogeneous nuclear ribonucleoprotein A1 OS=Homo sapiens OX=9606 GN=HNRNPA1 PE=1 SV=5 9.7 2269.5 - 3.25E+06 - - - -0.6386 - 3.732 0.673 - 634.9 1 2 0 -0.0011 16 0 0 0 1.38E+08 1.06E+08 - - - 9.4221 1 221125_WJC_METTL3_EV_vs_WT_F08.11844.11844.4 3.25E-08 21/120 K.VLHEAEGHIVTC[160.03]ETNTGEVYR[166.11].G "sp|P62318|SMD3_HUMAN,tr|H3BT13|H3BT13_HUMAN" 2 2423.1415 1.71 116114 11844 4 2423.135544 606.7926 Small nuclear ribonucleoprotein Sm D3 OS=Homo sapiens OX=9606 GN=SNRPD3 PE=1 SV=1 4.87 2269.6 - 3.13E+07 - - - -2.4551 - 4.388 0.615 - 335.3 1 2 0 -0.0059 21 0 0 0 1.03E+09 6.04E+08 - - - 5.0663 1 221125_WJC_METTL3_EV_vs_WT_F08.11845.11845.2 2.18E-14 25/42 R.LLEGEDAHLSSQQASGQSYSSR.E sp|P08779|K1C16_HUMAN 1 2349.0833 999 116115 11845 2 2349.07798 1175.5489 "Keratin, type I cytoskeletal 16 OS=Homo sapiens OX=9606 GN=KRT16 PE=1 SV=4" 4.65 2269.8 - 965020 - - - -2.263 - 5.034 0.759 - 1391.1 1 2 0 -0.0053 22 0 0 0 1.50E+07 0.00E+00 - - - 8.6188 1 221125_WJC_METTL3_EV_vs_WT_F08.11847.11847.2 8.68E-07 15/20 L.ENYHFVDEHGK.D sp|Q14677|EPN4_HUMAN 1 1373.6 2.2 116117 11847 2 1373.601195 687.8073 Clathrin interactor 1 OS=Homo sapiens OX=9606 GN=CLINT1 PE=1 SV=1 5.28 2270 - 402178 - - - 0.8489 - 3.046 0.624 - 762.4 1 1 0 0.0012 11 0 0 0 9.40E+06 4.27E+06 - - - 6.6627 1 221125_WJC_METTL3_EV_vs_WT_F08.11848.11848.2 4.75E-11 21/40 K.VLHEAEGHIVTC[160.03]ETNTGEVYR[166.11].G "sp|P62318|SMD3_HUMAN,tr|H3BT13|H3BT13_HUMAN" 2 2423.1415 1.63 116118 11848 2 2423.134926 1212.578 Small nuclear ribonucleoprotein Sm D3 OS=Homo sapiens OX=9606 GN=SNRPD3 PE=1 SV=1 4.87 2270.2 - 320475 - - - -2.7101 - 4.121 0.72 - 746.2 1 2 0 -0.0066 21 0 0 0 1.32E+07 8.08E+06 - - - 7.8384 1 221125_WJC_METTL3_EV_vs_WT_F08.11851.11851.3 1.53E-14 26/80 K.VLHEAEGHIVTC[160.03]ETNTGEVYR[166.11].G "sp|P62318|SMD3_HUMAN,tr|H3BT13|H3BT13_HUMAN" 2 2423.1415 1.51 116119 11851 3 2423.133581 808.7211 Small nuclear ribonucleoprotein Sm D3 OS=Homo sapiens OX=9606 GN=SNRPD3 PE=1 SV=1 4.87 2270.6 - 2.85E+07 - - - -3.2652 - 4.871 0.646 - 697.5 1 2 0 -0.0079 21 0 0 0 9.30E+08 6.15E+08 - - - 9.536 1 221125_WJC_METTL3_EV_vs_WT_F08.11853.11853.4 5.84E-06 20/126 R.LLEGEDAHLSSQQASGQSYSSR.E sp|P08779|K1C16_HUMAN 1 2349.0833 31.55 116121 11853 4 2349.083472 588.2781 "Keratin, type I cytoskeletal 16 OS=Homo sapiens OX=9606 GN=KRT16 PE=1 SV=4" 4.65 2270.7 - 1.93E+06 - - - 0.0749 - 3.237 0.525 - 205.4 1 2 0 0.0002 22 0 0 0 2.04E+07 6.48E+05 - - - 4.1799 1 221125_WJC_METTL3_EV_vs_WT_F08.11854.11854.2 1.53E-06 18/26 K.K[136.11]SVEEGK[136.11]IDGIIDK[136.11].T sp|Q96A49|SYAP1_HUMAN 1 1553.8727 1.54 116122 11854 2 1553.872139 777.9436 Synapse-associated protein 1 OS=Homo sapiens OX=9606 GN=SYAP1 PE=1 SV=1 4.78 2270.9 - 660325 - - - -0.3533 - 4.033 0.433 - 859.1 1 2 1 -0.0005 14 0 0 0 1.20E+07 7.79E+06 - - - 5.7384 0.9899 221125_WJC_METTL3_EV_vs_WT_F08.11855.11855.3 0.000303 14/44 S.LENYHFVDEHGK[136.11].D sp|Q14677|EPN4_HUMAN 1 1494.6983 0.94 116123 11855 3 1494.693317 499.24 Clathrin interactor 1 OS=Homo sapiens OX=9606 GN=CLINT1 PE=1 SV=1 5.27 2271 - 634628 - - - -3.3291 - 2.653 0.52 - 233.2 1 1 0 -0.005 12 0 0 0 7.77E+06 8.23E+06 - - - 7.0406 0.9999 221125_WJC_METTL3_EV_vs_WT_F08.11858.11858.3 1.21E-05 Nov-64 R.LVK[136.11]PGNQNTQVTEAWNK[136.11].V "sp|Q9UQ80|PA2G4_HUMAN,tr|F8W0A3|F8W0A3_HUMAN,tr|F8VR77|F8VR77_HUMAN,tr|H0YIN7|H0YIN7_HUMAN" 4 1942.0243 0.13 116126 11858 3 1942.021931 648.3487 Proliferation-associated protein 2G4 OS=Homo sapiens OX=9606 GN=PA2G4 PE=1 SV=3 8.59 2271.4 - 540333 - - - -1.2327 - 2.137 0.4 - 78 1 2 0 -0.0024 17 0 0 0 5.06E+06 3.97E+07 - - - 4.9174 1 221125_WJC_METTL3_EV_vs_WT_F08.11859.11859.2 8.52E-09 15/32 R.ESGEEYESGSGSNSWER.K sp|Q5D862|FILA2_HUMAN 1 1888.7347 999 116127 11859 2 1888.731464 945.3746 Filaggrin-2 OS=Homo sapiens OX=9606 GN=FLG2 PE=1 SV=1 3.98 2271.5 - 527856 - - - -1.7366 - 2.839 0.735 - 527.4 1 2 0 -0.0033 17 0 0 0 9.12E+06 0.00E+00 - - - 7.0341 1 221125_WJC_METTL3_EV_vs_WT_F08.11860.11860.2 2.91E-10 13/20 L.ENYHFVDEHGK[136.11].D sp|Q14677|EPN4_HUMAN 1 1381.6142 2.2 116128 11860 2 1381.607317 691.8144 Clathrin interactor 1 OS=Homo sapiens OX=9606 GN=CLINT1 PE=1 SV=1 5.28 2271.6 - 423205 - - - -5.0028 - 2.708 0.697 - 541.6 1 1 0 -0.0069 11 0 0 0 9.40E+06 4.27E+06 - - - 6.8819 0.999 221125_WJC_METTL3_EV_vs_WT_F08.11863.11863.3 1.07E-10 16/56 D.KVQALEEANNDLENK.L sp|P35527|K1C9_HUMAN 1 1713.8533 30.09 116129 11863 3 1713.851846 572.2917 "Keratin, type I cytoskeletal 9 OS=Homo sapiens OX=9606 GN=KRT9 PE=1 SV=3" 4.41 2272 - 1.37E+06 - - - -0.8735 - 3.251 0.602 - 508.3 1 1 0 -0.0015 15 0 0 0 1.89E+07 6.28E+05 - - - 8.3276 1 221125_WJC_METTL3_EV_vs_WT_F08.11867.11867.3 1.05E-05 18/48 K.RVC[160.03]EEIAIIPSKK.L "sp|P08708|RS17_HUMAN,tr|H0YN73|H0YN73_HUMAN,tr|H3BNC9|H3BNC9_HUMAN,tr|H0YN88|H0YN88_HUMAN,tr|A0A075B716|A0A075B716_HUMAN" 5 1541.8599 1.27 116133 11867 3 1541.857357 514.9606 40S ribosomal protein S17 OS=Homo sapiens OX=9606 GN=RPS17 PE=1 SV=2 8.2 2272.4 - 1.23E+06 - - - -1.6811 - 2.938 0.535 - 573.7 1 2 0 -0.0026 13 0 0 0 1.22E+08 9.62E+07 - - - 7.426 1 221125_WJC_METTL3_EV_vs_WT_F08.11868.11868.2 1.16E-16 20/40 K.VLHEAEGHIVTC[160.03]ETNTGEVYR.G "sp|P62318|SMD3_HUMAN,tr|H3BT13|H3BT13_HUMAN" 2 2413.1332 1.63 116134 11868 2 2413.130211 1207.5739 Small nuclear ribonucleoprotein Sm D3 OS=Homo sapiens OX=9606 GN=SNRPD3 PE=1 SV=1 4.87 2272.5 - 716431 - - - -1.2482 - 4.109 0.677 - 681.1 1 2 0 -0.003 21 0 0 0 1.32E+07 8.08E+06 - - - 7.5147 0.9976 221125_WJC_METTL3_EV_vs_WT_F08.11874.11874.4 0.00135 14/90 K.C[160.03]SALATQYMHC[160.03]VNHAK[136.11].Q "sp|Q9NX63|MIC19_HUMAN,tr|C9JRZ6|C9JRZ6_HUMAN" 2 1897.8477 3.01 116138 11874 4 1897.845284 475.4692 MICOS complex subunit MIC19 OS=Homo sapiens OX=9606 GN=CHCHD3 PE=1 SV=1 8.06 2273.3 - 973278 - - - -1.2693 - 1.756 0.261 - 114.1 1 2 0 -0.0024 16 0 0 0 3.03E+07 1.01E+07 - - - 1.6954 1 221125_WJC_METTL3_EV_vs_WT_F08.11878.11878.2 1.02E-06 19/32 R.EIVHLQAGQC[160.03]GNQIGAK[136.11].F "sp|P04350|TBB4A_HUMAN,sp|Q9BVA1|TBB2B_HUMAN,sp|P07437|TBB5_HUMAN,sp|Q13509|TBB3_HUMAN,sp|Q13885|TBB2A_HUMAN,sp|P68371|TBB4B_HUMAN,tr|M0R2D3|M0R2D3_HUMAN,tr|G3V3W7|G3V3W7_HUMAN,tr|M0R2T4|M0R2T4_HUMAN,tr|G3V3R4|G3V3R4_HUMAN,tr|M0R042|M0R042_HUMAN,tr|M0QY85|M0QY85_HUMAN,tr|M0QZL7|M0QZL7_HUMAN,tr|G3V5W4|G3V5W4_HUMAN,tr|M0R0X0|M0R0X0_HUMAN,tr|M0QYM7|M0QYM7_HUMAN,tr|G3V4U2|G3V4U2_HUMAN,tr|M0R278|M0R278_HUMAN,tr|M0QY37|M0QY37_HUMAN,tr|G3V2R8|G3V2R8_HUMAN,tr|G3V3J6|G3V3J6_HUMAN,tr|M0QX14|M0QX14_HUMAN,tr|G3V2N6|G3V2N6_HUMAN" 23 1829.9298 0.61 116142 11878 2 1829.92764 915.9722 Tubulin beta-4A chain OS=Homo sapiens OX=9606 GN=TUBB4A PE=1 SV=2 6.83 2273.7 - 700987 - - - -1.1618 - 3.582 0.619 - 1111.3 1 2 0 -0.0021 17 0 0 0 1.10E+07 1.79E+07 - - - 6.7492 0.9993 221125_WJC_METTL3_EV_vs_WT_F08.11883.11883.3 0.000133 Nov-52 R.DK[136.11]EC[160.03]GQLLISENQK[136.11].V "sp|Q8IWS0|PHF6_HUMAN,tr|Q5JRC6|Q5JRC6_HUMAN,tr|A0A0D9SGE8|A0A0D9SGE8_HUMAN" 3 1676.8374 0.65 116145 11883 3 1676.835512 559.9531 PHD finger protein 6 OS=Homo sapiens OX=9606 GN=PHF6 PE=1 SV=1 4.68 2274.3 - 2.30E+06 - - - -1.1468 - 2.151 0.389 - 140 1 2 1 -0.0019 14 0 0 0 1.24E+08 1.91E+08 - - - 4.9119 0.9999 221125_WJC_METTL3_EV_vs_WT_F08.11884.11884.3 9.79E-08 Dec-72 R.TDTAVQATGSVPSTPIAHR[166.11].G "sp|Q9NXR1|NDE1_HUMAN,tr|I3L522|I3L522_HUMAN,tr|I3L533|I3L533_HUMAN,tr|A0A6Q8PEY3|A0A6Q8PEY3_HUMAN,tr|I3L3G9|I3L3G9_HUMAN,tr|A0A6Q8PGV6|A0A6Q8PGV6_HUMAN,tr|I3L2R3|I3L2R3_HUMAN,tr|A0A6Q8PG46|A0A6Q8PG46_HUMAN,tr|I3L2R9|I3L2R9_HUMAN,tr|A0A0J9YY14|A0A0J9YY14_HUMAN" 10 1917.9784 2.44 116146 11884 3 1917.979361 640.3334 Nuclear distribution protein nudE homolog 1 OS=Homo sapiens OX=9606 GN=NDE1 PE=1 SV=3 6.41 2274.4 - 667054 - - - 0.5146 - 2.731 0.434 - 104.6 1 2 0 0.001 19 0 0 0 1.47E+07 5.99E+06 - - - 5.8467 1 221125_WJC_METTL3_EV_vs_WT_F08.11885.11885.2 2.48E-08 18/26 K.KITESVAETAQTIK.K sp|Q96A49|SYAP1_HUMAN 1 1517.8301 1.56 116147 11885 2 1517.829817 759.9223 Synapse-associated protein 1 OS=Homo sapiens OX=9606 GN=SYAP1 PE=1 SV=1 6.14 2274.6 - 381217 - - - -0.1785 - 4.07 0.606 - 863.3 1 2 0 -0.0003 14 0 0 0 1.22E+07 7.78E+06 - - - 7.0392 1 221125_WJC_METTL3_EV_vs_WT_F08.11889.11889.2 9.77E-08 16/26 K.K[136.11]ITESVAETAQTIK[136.11].K sp|Q96A49|SYAP1_HUMAN 1 1533.8585 1.56 116149 11889 2 1533.855682 767.9365 Synapse-associated protein 1 OS=Homo sapiens OX=9606 GN=SYAP1 PE=1 SV=1 6.14 2275.1 - 388807 - - - -1.8294 - 3.533 0.562 - 560.6 1 2 0 -0.0028 14 0 0 0 1.22E+07 7.78E+06 - - - 6.3583 1 221125_WJC_METTL3_EV_vs_WT_F08.11891.11891.3 1.09E-10 17/72 R.TDTAVQATGSVPSTPIAHR.G "sp|Q9NXR1|NDE1_HUMAN,tr|I3L522|I3L522_HUMAN,tr|I3L533|I3L533_HUMAN,tr|A0A6Q8PEY3|A0A6Q8PEY3_HUMAN,tr|I3L3G9|I3L3G9_HUMAN,tr|A0A6Q8PGV6|A0A6Q8PGV6_HUMAN,tr|I3L2R3|I3L2R3_HUMAN,tr|A0A6Q8PG46|A0A6Q8PG46_HUMAN,tr|I3L2R9|I3L2R9_HUMAN,tr|A0A0J9YY14|A0A0J9YY14_HUMAN" 10 1907.9701 2.46 116151 11891 3 1907.970859 636.9973 Nuclear distribution protein nudE homolog 1 OS=Homo sapiens OX=9606 GN=NDE1 PE=1 SV=3 6.41 2275.3 - 744443 - - - 0.3957 - 3.611 0.622 - 256.1 1 2 0 0.0008 19 0 0 0 1.47E+07 5.99E+06 - - - 8.629 1 221125_WJC_METTL3_EV_vs_WT_F08.11892.11892.2 2.08E-06 16/32 R.EIVHLQAGQC[160.03]GNQIGAK.F "sp|P04350|TBB4A_HUMAN,sp|Q9BVA1|TBB2B_HUMAN,sp|P07437|TBB5_HUMAN,sp|Q13509|TBB3_HUMAN,sp|Q13885|TBB2A_HUMAN,sp|P68371|TBB4B_HUMAN,tr|M0R2D3|M0R2D3_HUMAN,tr|G3V3W7|G3V3W7_HUMAN,tr|M0R2T4|M0R2T4_HUMAN,tr|G3V3R4|G3V3R4_HUMAN,tr|M0R042|M0R042_HUMAN,tr|M0QY85|M0QY85_HUMAN,tr|M0QZL7|M0QZL7_HUMAN,tr|G3V5W4|G3V5W4_HUMAN,tr|M0R0X0|M0R0X0_HUMAN,tr|M0QYM7|M0QYM7_HUMAN,tr|G3V4U2|G3V4U2_HUMAN,tr|M0R278|M0R278_HUMAN,tr|M0QY37|M0QY37_HUMAN,tr|G3V2R8|G3V2R8_HUMAN,tr|G3V3J6|G3V3J6_HUMAN,tr|M0QX14|M0QX14_HUMAN,tr|G3V2N6|G3V2N6_HUMAN" 23 1821.9156 0.61 116152 11892 2 1821.912628 911.9651 Tubulin beta-4A chain OS=Homo sapiens OX=9606 GN=TUBB4A PE=1 SV=2 6.83 2275.5 - 689016 - - - -1.6126 - 3.375 0.602 - 674.8 1 2 0 -0.0029 17 0 0 0 1.10E+07 1.79E+07 - - - 6.477 0.9972 221125_WJC_METTL3_EV_vs_WT_F08.11897.11897.2 0.0897 12-Jul R.LAADDFR.T "sp|Q04695|K1C17_HUMAN,sp|P13645|K1C10_HUMAN,sp|O76015|KRT38_HUMAN,sp|Q2M2I5|K1C24_HUMAN,sp|Q15323|K1H1_HUMAN,sp|P02533|K1C14_HUMAN,sp|P05783|K1C18_HUMAN,sp|P08727|K1C19_HUMAN,sp|P08779|K1C16_HUMAN,sp|Q7Z3Y7|K1C28_HUMAN,sp|Q14532|K1H2_HUMAN,sp|P19012|K1C15_HUMAN,sp|O76013|KRT36_HUMAN,sp|Q14525|KT33B_HUMAN,sp|Q92764|KRT35_HUMAN,sp|O76014|KRT37_HUMAN,sp|P13646|K1C13_HUMAN,tr|F8VZY9|F8VZY9_HUMAN,tr|K7EPJ9|K7EPJ9_HUMAN,tr|C9JM50|C9JM50_HUMAN,tr|A0A1B0GVI3|A0A1B0GVI3_HUMAN,tr|K7EMD9|K7EMD9_HUMAN,tr|F5GWP8|F5GWP8_HUMAN,tr|K7ERE3|K7ERE3_HUMAN,tr|C4AM86|C4AM86_HUMAN" 25 806.3923 49.25 116155 11897 2 806.390532 404.2034 "Keratin, type I cytoskeletal 17 OS=Homo sapiens OX=9606 GN=KRT17 PE=1 SV=2" 4.21 2276.1 - 1.36E+06 - - - -2.1516 - 1.555 0.244 - 178.7 1 2 0 -0.0017 7 0 0 0 2.07E+07 4.20E+05 - - - 2.2415 0.9999 221125_WJC_METTL3_EV_vs_WT_F08.11898.11898.3 4.64E-05 Dec-52 R.DKEC[160.03]GQLLISENQK.V "sp|Q8IWS0|PHF6_HUMAN,tr|Q5JRC6|Q5JRC6_HUMAN,tr|A0A0D9SGE8|A0A0D9SGE8_HUMAN" 3 1660.809 0.65 116156 11898 3 1660.807618 554.6103 PHD finger protein 6 OS=Homo sapiens OX=9606 GN=PHF6 PE=1 SV=1 4.68 2276.2 - 3.80E+06 - - - -0.8532 - 2.617 0.489 - 157 1 2 1 -0.0014 14 0 0 0 1.23E+08 1.89E+08 - - - 6.5481 1 221125_WJC_METTL3_EV_vs_WT_F08.11900.11900.4 4.89E-11 20/72 K.RVC[160.03]EEIAIIPSKK.L "sp|P08708|RS17_HUMAN,tr|H0YN73|H0YN73_HUMAN,tr|H3BNC9|H3BNC9_HUMAN,tr|H0YN88|H0YN88_HUMAN,tr|A0A075B716|A0A075B716_HUMAN" 5 1541.8599 1.42 116158 11900 4 1541.858293 386.4723 40S ribosomal protein S17 OS=Homo sapiens OX=9606 GN=RPS17 PE=1 SV=2 8.2 2276.4 - 920353 - - - -1.074 - 3.046 0.583 - 420.5 1 2 0 -0.0017 13 0 0 0 2.88E+07 2.03E+07 - - - 4.7129 0.9987 221125_WJC_METTL3_EV_vs_WT_F08.11902.11902.2 1.93E-05 26-Oct R.DK[136.11]EC[160.03]GQLLISENQK[136.11].V "sp|Q8IWS0|PHF6_HUMAN,tr|Q5JRC6|Q5JRC6_HUMAN,tr|A0A0D9SGE8|A0A0D9SGE8_HUMAN" 3 1676.8374 0.63 116160 11902 2 1676.83736 839.426 PHD finger protein 6 OS=Homo sapiens OX=9606 GN=PHF6 PE=1 SV=1 4.68 2276.6 - 535186 - - - -0.0447 - 2.491 0.493 - 202 1 2 1 -0.0001 14 0 0 0 7.51E+06 1.19E+07 - - - 4.9726 0.9892 221125_WJC_METTL3_EV_vs_WT_F08.11906.11906.2 3.15 18-Oct P.ELATDPELEK[136.11].K "sp|Q86U44|MTA70_HUMAN,tr|B4E349|B4E349_HUMAN,tr|F5H6D8|F5H6D8_HUMAN,tr|H0YFV6|H0YFV6_HUMAN,tr|B4DTN4|B4DTN4_HUMAN" 5 1151.5801 0.01 116162 11906 2 1151.579254 576.7973 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 4 2277.1 - 2.49E+06 - - - -0.7642 - 2.183 0.424 - 384.5 1 1 0 -0.0009 10 0 0 0 3.60E+05 5.21E+07 - - - 4.3516 0.9999 221125_WJC_METTL3_EV_vs_WT_F08.11907.11907.3 1.55E-07 14/56 K.AK[136.11]DLQDELAGNSEQR[166.11].K sp|Q9UQE7|SMC3_HUMAN 1 1690.8241 0.62 116163 11907 3 1690.822944 564.6153 Structural maintenance of chromosomes protein 3 OS=Homo sapiens OX=9606 GN=SMC3 PE=1 SV=2 4.32 2277.2 - 1.24E+06 - - - -0.6908 - 2.755 0.507 - 277.6 1 2 1 -0.0012 15 0 0 0 1.57E+07 2.52E+07 - - - 6.8366 1 221125_WJC_METTL3_EV_vs_WT_F08.11908.11908.2 5.06E-07 21/36 S.SLVSGLNSSASEPAK[136.11]EPAK[136.11].K "sp|Q86U44|MTA70_HUMAN,tr|F5H6D8|F5H6D8_HUMAN,tr|H0YFV6|H0YFV6_HUMAN,tr|B4DTN4|B4DTN4_HUMAN" 4 1886.992 0.001 116164 11908 2 1886.988134 944.5033 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 5.86 2277.3 - 943800 - - - -2.0604 - 3.95 0.618 - 1355.3 1 1 1 -0.0039 19 0 0 0 0.00E+00 3.02E+07 - - - 6.9817 0.9816 221125_WJC_METTL3_EV_vs_WT_F08.11909.11909.3 0.0357 Aug-64 R.LVKPGNQNTQVTEAWNK.V "sp|Q9UQ80|PA2G4_HUMAN,tr|F8W0A3|F8W0A3_HUMAN,tr|F8VR77|F8VR77_HUMAN,tr|H0YIN7|H0YIN7_HUMAN" 4 1925.9959 0.13 116165 11909 3 1925.989649 643.0059 Proliferation-associated protein 2G4 OS=Homo sapiens OX=9606 GN=PA2G4 PE=1 SV=3 8.59 2277.5 - 240353 - - - -3.2586 - 1.552 0.243 - 61.2 1 2 0 -0.0063 17 0 0 0 5.06E+06 3.97E+07 - - - 2.3579 1 221125_WJC_METTL3_EV_vs_WT_F08.11912.11912.3 2.09E-07 19/48 K.R[166.11]VC[160.03]EEIAIIPSK[136.11]K[136.11].L "sp|P08708|RS17_HUMAN,tr|H0YN73|H0YN73_HUMAN,tr|H3BNC9|H3BNC9_HUMAN,tr|H0YN88|H0YN88_HUMAN,tr|A0A075B716|A0A075B716_HUMAN" 5 1567.8966 1.27 116166 11912 3 1567.896358 523.6395 40S ribosomal protein S17 OS=Homo sapiens OX=9606 GN=RPS17 PE=1 SV=2 8.2 2277.9 - 4.15E+06 - - - -0.1665 - 3.229 0.511 - 466.3 1 2 0 -0.0003 13 0 0 0 1.22E+08 9.62E+07 - - - 7.4152 1 221125_WJC_METTL3_EV_vs_WT_F08.11913.11913.3 6.46E-08 15/52 K.KITESVAETAQTIK.K sp|Q96A49|SYAP1_HUMAN 1 1517.8301 1.13 116167 11913 3 1517.830231 506.9506 Synapse-associated protein 1 OS=Homo sapiens OX=9606 GN=SYAP1 PE=1 SV=1 6.14 2278 - 1.62E+06 - - - 0.0942 - 3.27 0.403 - 531 1 2 0 0.0001 14 0 0 0 2.10E+07 1.85E+07 - - - 6.1816 1 221125_WJC_METTL3_EV_vs_WT_F08.11915.11915.3 1.02E-06 14/52 K.K[136.11]ITESVAETAQTIK[136.11].K sp|Q96A49|SYAP1_HUMAN 1 1533.8585 1.13 116169 11915 3 1533.856941 512.2934 Synapse-associated protein 1 OS=Homo sapiens OX=9606 GN=SYAP1 PE=1 SV=1 6.14 2278.2 - 1.23E+06 - - - -1.0086 - 3.242 0.409 - 357 1 2 0 -0.0015 14 0 0 0 2.10E+07 1.85E+07 - - - 6.2253 1 221125_WJC_METTL3_EV_vs_WT_F08.11916.11916.2 2.29E-06 13/26 R.DKEC[160.03]GQLLISENQK.V "sp|Q8IWS0|PHF6_HUMAN,tr|Q5JRC6|Q5JRC6_HUMAN,tr|A0A0D9SGE8|A0A0D9SGE8_HUMAN" 3 1660.809 0.63 116170 11916 2 1660.80602 831.4118 PHD finger protein 6 OS=Homo sapiens OX=9606 GN=PHF6 PE=1 SV=1 4.68 2278.4 - 307666 - - - -1.8154 - 3.017 0.577 - 526 1 2 1 -0.003 14 0 0 0 7.51E+06 1.19E+07 - - - 6.0729 1 221125_WJC_METTL3_EV_vs_WT_F08.11917.11917.2 2.27E-11 17/32 L.VSGLNSSASEPAK[136.11]EPAK[136.11].K "sp|Q86U44|MTA70_HUMAN,tr|F5H6D8|F5H6D8_HUMAN,tr|H0YFV6|H0YFV6_HUMAN,tr|B4DTN4|B4DTN4_HUMAN" 4 1686.8759 0.001 116171 11917 2 1686.875087 844.4452 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 6.11 2278.5 - 179162 - - - -0.4991 - 3.152 0.689 - 832.8 1 1 1 -0.0008 17 0 0 0 0.00E+00 8.36E+05 - - - 6.9522 1 221125_WJC_METTL3_EV_vs_WT_F08.11921.11921.3 8.06E-09 19/76 K.LPQQSHSAFGATSSSSGFGK.S "sp|Q86XP3|DDX42_HUMAN,tr|J3QRI2|J3QRI2_HUMAN,tr|J3KTK9|J3KTK9_HUMAN" 3 1979.9337 0.26 116173 11921 3 1979.938463 660.9852 ATP-dependent RNA helicase DDX42 OS=Homo sapiens OX=9606 GN=DDX42 PE=1 SV=1 8.76 2279 - 621869 - - - 2.3965 - 3.684 0.614 - 475.8 1 2 0 0.0047 20 0 0 0 1.04E+07 3.96E+07 - - - 8.5477 1 221125_WJC_METTL3_EV_vs_WT_F08.11922.11922.2 3.30E-08 15/32 R.GSGGLGGAC[160.03]GGAGFGSR.S "sp|P48668|K2C6C_HUMAN,sp|P04259|K2C6B_HUMAN,sp|P02538|K2C6A_HUMAN" 3 1423.6263 999 116174 11922 2 1423.625053 712.8204 "Keratin, type II cytoskeletal 6C OS=Homo sapiens OX=9606 GN=KRT6C PE=1 SV=3" 8.25 2279.1 - 797870 - - - -0.8478 - 3.262 0.624 - 556.9 1 2 0 -0.0012 17 0 0 0 1.62E+07 0.00E+00 - - - 6.5563 0.9731 221125_WJC_METTL3_EV_vs_WT_F08.11925.11925.3 1.59 Aug-36 R.LKYENEVALR.Q "sp|P13645|K1C10_HUMAN,tr|A0A1B0GVI3|A0A1B0GVI3_HUMAN" 2 1233.6717 0.44 116177 11925 3 1233.671929 412.2312 "Keratin, type I cytoskeletal 10 OS=Homo sapiens OX=9606 GN=KRT10 PE=1 SV=6" 6.14 2279.5 - 433247 - - - 0.1556 - 1.369 0.239 - 66.6 1 2 1 0.0002 10 0 0 0 5.25E+07 1.18E+08 - - - 2.1218 0.9998 221125_WJC_METTL3_EV_vs_WT_F08.11927.11927.3 0.00386 Oct-52 R.IEDVTPIPSDSTR[166.11]R[166.11].K "sp|P62263|RS14_HUMAN,tr|A0A2R8Y811|A0A2R8Y811_HUMAN" 2 1604.8273 1.61 116179 11927 3 1604.829754 535.9497 40S ribosomal protein S14 OS=Homo sapiens OX=9606 GN=RPS14 PE=1 SV=3 4.56 2279.8 - 342962 - - - 1.5354 - 2.308 0.39 - 104.2 1 2 0 0.0025 14 0 0 0 7.17E+07 4.44E+07 - - - 5.1101 1 221125_WJC_METTL3_EV_vs_WT_F08.11928.11928.2 9.23E-11 14/30 K.SPSSDSWTC[160.03]ADTSTER.R "sp|Q8N6T3|ARFG1_HUMAN,tr|F8VWH9|F8VWH9_HUMAN,tr|H0YIQ0|H0YIQ0_HUMAN,tr|E5RHH7|E5RHH7_HUMAN" 4 1785.7112 1.96 116180 11928 2 1785.709586 893.8629 ADP-ribosylation factor GTPase-activating protein 1 OS=Homo sapiens OX=9606 GN=ARFGAP1 PE=1 SV=2 4.03 2279.9 - 237693 - - - -0.8882 - 2.997 0.756 - 629.8 1 2 0 -0.0016 16 0 0 0 3.28E+06 1.68E+06 - - - 7.3228 1 221125_WJC_METTL3_EV_vs_WT_F08.11931.11931.4 1.44E-06 17/72 K.R[166.11]VC[160.03]EEIAIIPSK[136.11]K[136.11].L "sp|P08708|RS17_HUMAN,tr|H0YN73|H0YN73_HUMAN,tr|H3BNC9|H3BNC9_HUMAN,tr|H0YN88|H0YN88_HUMAN,tr|A0A075B716|A0A075B716_HUMAN" 5 1567.8966 1.42 116181 11931 4 1567.894267 392.9814 40S ribosomal protein S17 OS=Homo sapiens OX=9606 GN=RPS17 PE=1 SV=2 8.2 2280.3 - 844118 - - - -1.5001 - 2.758 0.538 - 243.8 1 2 0 -0.0024 13 0 0 0 2.88E+07 2.03E+07 - - - 4.2842 0.9998 221125_WJC_METTL3_EV_vs_WT_F08.11933.11933.3 0.000961 15/56 K.KLNYEENKEESLLEK.R sp|O95347|SMC2_HUMAN 1 1864.9418 0.03 116183 11933 3 1864.940124 622.6546 Structural maintenance of chromosomes protein 2 OS=Homo sapiens OX=9606 GN=SMC2 PE=1 SV=2 4.65 2280.6 - 803951 - - - -0.9116 - 2.254 0.468 - 77.8 1 2 1 -0.0017 15 0 0 0 1.84E+07 7.16E+08 - - - 5.8779 0.9999 221125_WJC_METTL3_EV_vs_WT_F08.11936.11936.3 0.00023 15/52 R.IEDVTPIPSDSTRR.K "sp|P62263|RS14_HUMAN,tr|A0A2R8Y811|A0A2R8Y811_HUMAN" 2 1584.8108 1.23 116186 11936 3 1584.814699 529.2775 40S ribosomal protein S14 OS=Homo sapiens OX=9606 GN=RPS14 PE=1 SV=3 4.56 2280.9 - 496922 - - - 2.4918 - 3.002 0.416 - 393.4 1 2 0 0.0039 14 0 0 0 5.08E+07 4.12E+07 - - - 6.0983 1 221125_WJC_METTL3_EV_vs_WT_F08.11946.11946.3 0.000104 16/44 R.R[166.11]HEQFIPIAADK[136.11].R "sp|Q9Y520|PRC2C_HUMAN,tr|E7EPN9|E7EPN9_HUMAN" 2 1441.7797 1.07 116194 11946 3 1441.77796 481.6005 Protein PRRC2C OS=Homo sapiens OX=9606 GN=PRRC2C PE=1 SV=4 6.75 2282.1 - 1.94E+06 - - - -1.1846 - 2.44 0.48 - 588.4 1 2 0 -0.0017 12 0 0 0 7.14E+07 6.65E+07 - - - 6.3635 1 221125_WJC_METTL3_EV_vs_WT_F08.11947.11947.3 2.39E-05 13/44 R.DAEDALHNLDRK.W "sp|O75494|SRS10_HUMAN,tr|Q5JRI1|Q5JRI1_HUMAN" 2 1395.6743 1.9 116195 11947 3 1395.673311 466.232 Serine\arginine-rich splicing factor 10 OS=Homo sapiens OX=9606 GN=SRSF10 PE=1 SV=1 4.66 2282.2 - 2.95E+06 - - - -0.6771 - 2.468 0.509 - 244.5 1 2 0 -0.0009 12 0 0 0 1.28E+08 6.76E+07 - - - 6.7187 1 221125_WJC_METTL3_EV_vs_WT_F08.11954.11954.3 3.44E-07 15/60 R.C[160.03]VSVQTDPTDEIPTKK.S sp|P18583|SON_HUMAN 1 1816.8877 0.59 116200 11954 3 1816.885984 606.6365 Protein SON OS=Homo sapiens OX=9606 GN=SON PE=1 SV=4 4.56 2282.9 - 5.17E+06 - - - -0.9335 - 2.615 0.534 - 212.4 1 2 0 -0.0017 16 0 0 0 1.24E+08 2.12E+08 - - - 6.9596 1 221125_WJC_METTL3_EV_vs_WT_F08.11956.11956.3 0.000522 14/44 R.RHEQFIPIAADK.R "sp|Q9Y520|PRC2C_HUMAN,tr|E7EPN9|E7EPN9_HUMAN" 2 1423.7572 1.07 116202 11956 3 1423.756759 475.593 Protein PRRC2C OS=Homo sapiens OX=9606 GN=PRRC2C PE=1 SV=4 6.75 2283.1 - 2.31E+06 - - - -0.3083 - 2.504 0.492 - 375.1 1 2 0 -0.0004 12 0 0 0 7.14E+07 6.68E+07 - - - 6.5694 1 221125_WJC_METTL3_EV_vs_WT_F08.11957.11957.3 6.43E-10 24/56 R.KAIVIC[160.03]PTDEDLKDR.T "sp|Q9BUJ2|HNRL1_HUMAN,tr|A0A0A0MRA5|A0A0A0MRA5_HUMAN,tr|M0R3F1|M0R3F1_HUMAN,tr|B7Z4B8|B7Z4B8_HUMAN" 4 1771.9138 1.48 116203 11957 3 1771.913245 591.6452 Heterogeneous nuclear ribonucleoprotein U-like protein 1 OS=Homo sapiens OX=9606 GN=HNRNPUL1 PE=1 SV=2 4.68 2283.2 - 1.10E+06 - - - -0.333 - 4.742 0.635 - 1033 1 2 1 -0.0006 15 0 0 0 1.25E+08 8.42E+07 - - - 9.6808 0.9999 221125_WJC_METTL3_EV_vs_WT_F08.11960.11960.4 1.63E-10 17/84 R.KAIVIC[160.03]PTDEDLKDR.T "sp|Q9BUJ2|HNRL1_HUMAN,tr|A0A0A0MRA5|A0A0A0MRA5_HUMAN,tr|M0R3F1|M0R3F1_HUMAN,tr|B7Z4B8|B7Z4B8_HUMAN" 4 1771.9138 1.57 116206 11960 4 1771.914378 443.9857 Heterogeneous nuclear ribonucleoprotein U-like protein 1 OS=Homo sapiens OX=9606 GN=HNRNPUL1 PE=1 SV=2 4.68 2283.5 - 421455 - - - 0.3064 - 3.174 0.612 - 279.5 1 2 1 0.0005 15 0 0 0 5.04E+07 3.22E+07 - - - 4.966 0.9998 221125_WJC_METTL3_EV_vs_WT_F08.11962.11962.2 4.46E-06 30-Sep R.C[160.03]VSVQTDPTDEIPTKK.S sp|P18583|SON_HUMAN 1 1816.8877 2.11 116208 11962 2 1816.884145 909.4511 Protein SON OS=Homo sapiens OX=9606 GN=SON PE=1 SV=4 4.56 2283.8 - 239696 - - - -1.9456 - 2.049 0.555 - 199.3 1 2 0 -0.0035 16 0 0 0 3.12E+06 1.48E+06 - - - 4.9028 1 221125_WJC_METTL3_EV_vs_WT_F08.11966.11966.3 1.76E-06 14/44 R.DAEDALHNLDR[166.11]K[136.11].W "sp|O75494|SRS10_HUMAN,tr|Q5JRI1|Q5JRI1_HUMAN" 2 1413.6967 1.88 116210 11966 3 1413.695779 472.2395 Serine\arginine-rich splicing factor 10 OS=Homo sapiens OX=9606 GN=SRSF10 PE=1 SV=1 4.66 2284.3 - 3.43E+06 - - - -0.6699 - 2.903 0.456 - 279.8 1 2 0 -0.0009 12 0 0 0 1.27E+08 6.76E+07 - - - 6.5778 1 221125_WJC_METTL3_EV_vs_WT_F08.11969.11969.3 0.000217 16/44 R.HNAEVAAFHLDR.L sp|O75063|XYLK_HUMAN 1 1378.6742 0.9 116213 11969 3 1378.67143 460.5653 Glycosaminoglycan xylosylkinase OS=Homo sapiens OX=9606 GN=FAM20B PE=1 SV=1 5.99 2284.6 - 679670 - - - -2.0063 - 3.297 0.493 - 330.6 1 2 0 -0.0028 12 0 0 0 1.18E+07 1.31E+07 - - - 7.3426 0.9998 221125_WJC_METTL3_EV_vs_WT_F08.11971.11971.3 1.09E-05 Nov-56 K.GSENKTDLDNSIGIK.K sp|Q9H501|ESF1_HUMAN 1 1589.7897 0.48 116215 11971 3 1589.789721 530.9372 ESF1 homolog OS=Homo sapiens OX=9606 GN=ESF1 PE=1 SV=1 4.56 2284.9 - 462641 - - - 0.0258 - 2.316 0.499 - 151.3 1 2 1 0 15 0 0 0 2.39E+07 4.98E+07 - - - 6.2948 0.9236 221125_WJC_METTL3_EV_vs_WT_F08.11972.11972.4 0.00211 Nov-90 Y.ATVEEVDAAMNARPHK.V "sp|P09651|ROA1_HUMAN,tr|A0A7I2YQX9|A0A7I2YQX9_HUMAN,tr|A0A7I2V3W4|A0A7I2V3W4_HUMAN,tr|F8W646|F8W646_HUMAN,tr|F8VZ49|F8VZ49_HUMAN,tr|A0A7I2V3R8|A0A7I2V3R8_HUMAN,tr|F8W6I7|F8W6I7_HUMAN,tr|F8VYN5|F8VYN5_HUMAN,tr|A0A7I2V2L6|A0A7I2V2L6_HUMAN,tr|A0A7I2V3C7|A0A7I2V3C7_HUMAN,tr|A0A7I2V3W0|A0A7I2V3W0_HUMAN,tr|A0A7I2YQV3|A0A7I2YQV3_HUMAN,tr|A0A2R8Y4L2|A0A2R8Y4L2_HUMAN,tr|A0A7I2V2Z4|A0A7I2V2Z4_HUMAN,tr|A0A7I2V4M0|A0A7I2V4M0_HUMAN" 15 1737.8468 1.55 116216 11972 4 1737.846971 435.469 Heterogeneous nuclear ribonucleoprotein A1 OS=Homo sapiens OX=9606 GN=HNRNPA1 PE=1 SV=5 5.45 2285 - 409291 - - - 0.088 - 2.33 0.309 - 85.7 1 1 0 0.0002 16 0 0 0 1.04E+07 6.74E+06 - - - 2.2135 0.9999 221125_WJC_METTL3_EV_vs_WT_F08.11982.11982.3 0.000421 14/64 R.AAHTEDINAC[160.03]TLTTSPR[166.11].L "sp|P04049|RAF1_HUMAN,tr|H7C155|H7C155_HUMAN" 2 1866.8769 0.75 116222 11982 3 1866.871218 623.2996 RAF proto-oncogene serine\threonine-protein kinase OS=Homo sapiens OX=9606 GN=RAF1 PE=1 SV=1 5.32 2286.2 - 1.16E+06 - - - -3.0682 - 2.544 0.519 - 106.4 1 2 0 -0.0057 17 0 0 0 2.66E+07 3.55E+07 - - - 6.6837 1 221125_WJC_METTL3_EV_vs_WT_F08.11983.11983.3 1.26E-08 16/64 K.QPC[160.03]PSESDIITEEDK[136.11]SK[136.11].K sp|O75475|PSIP1_HUMAN 1 1977.9172 1.4 116223 11983 3 1977.916695 660.313 PC4 and SFRS1-interacting protein OS=Homo sapiens OX=9606 GN=PSIP1 PE=1 SV=1 4.18 2286.3 - 674492 - - - -0.2563 - 2.877 0.621 - 290.8 1 2 1 -0.0005 17 0 0 0 5.22E+07 3.74E+07 - - - 8.1331 0.986 221125_WJC_METTL3_EV_vs_WT_F08.11984.11984.2 0.0032 16-Nov R.K[136.11]IELFGR[166.11]PH.N sp|Q86U44|MTA70_HUMAN 1 1113.6414 0.001 116224 11984 2 1113.640276 557.828 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 8.75 2286.4 - 1.83E+06 - - - -0.994 - 2.262 0.365 - 438.9 1 1 0 -0.0011 9 0 0 0 0.00E+00 3.72E+07 - - - 4.098 0.9962 221125_WJC_METTL3_EV_vs_WT_F08.11989.11989.4 0.00429 Sep-90 R.K[136.11]VENEDMNK[136.11]DQILLEK[136.11].E "sp|Q15019|SEPT2_HUMAN,tr|H7C2Y0|H7C2Y0_HUMAN,tr|B5MCX3|B5MCX3_HUMAN" 3 1969.0252 0.79 116229 11989 4 1969.023982 493.2636 Septin-2 OS=Homo sapiens OX=9606 GN=SEPTIN2 PE=1 SV=1 4.51 2287.1 - 382006 - - - -0.6404 - 1.876 0.302 - 63.5 1 2 1 -0.0013 16 0 0 0 3.72E+06 4.73E+06 - - - 2.0759 0.9993 221125_WJC_METTL3_EV_vs_WT_F08.11990.11990.3 5.33E-09 16/64 K.LQQLK[136.11]DETGELSSADEK[136.11].R sp|Q92900|RENT1_HUMAN 1 1905.9502 0.78 116230 11990 3 1905.941243 636.324 Regulator of nonsense transcripts 1 OS=Homo sapiens OX=9606 GN=UPF1 PE=1 SV=2 4.18 2287.2 - 368349 - - - -4.7079 - 3.21 0.575 - 349.6 1 2 1 -0.009 17 0 0 0 1.13E+07 1.44E+07 - - - 7.8945 1 221125_WJC_METTL3_EV_vs_WT_F08.11992.11992.3 4.70E-06 19/92 K.GEAAPGPAPPAPEATPPPASAAGK.D "sp|Q9NSI2|SLX9_HUMAN,tr|C9JJU7|C9JJU7_HUMAN" 2 2108.0538 3.19 116231 11992 3 2108.052647 703.6919 Ribosome biogenesis protein SLX9 homolog OS=Homo sapiens OX=9606 GN=SLX9 PE=1 SV=2 4.53 2287.4 - 6.46E+06 - - - -0.5631 - 3.236 0.548 - 294.3 1 2 0 -0.0012 24 0 0 0 1.27E+08 3.99E+07 - - - 7.3768 1 221125_WJC_METTL3_EV_vs_WT_F08.11996.11996.4 2.31E-07 19/84 R.YTLHVVDSPTVK[136.11]PSR[166.11].D sp|Q8N6R0|EFNMT_HUMAN 1 1715.9325 2.23 116233 11996 4 1715.931261 429.9904 eEF1A lysine and N-terminal methyltransferase OS=Homo sapiens OX=9606 GN=METTL13 PE=1 SV=1 8.6 2287.9 - 497103 - - - -0.7454 - 3.115 0.494 - 238.3 1 2 0 -0.0013 15 0 0 0 1.48E+08 6.65E+07 - - - 3.932 0.9987 221125_WJC_METTL3_EV_vs_WT_F08.11997.11997.3 0.00223 13/60 R.K[136.11]VENEDMNK[136.11]DQILLEK[136.11].E "sp|Q15019|SEPT2_HUMAN,tr|H7C2Y0|H7C2Y0_HUMAN,tr|B5MCX3|B5MCX3_HUMAN" 3 1969.0252 2.83 116234 11997 3 1969.026323 657.349 Septin-2 OS=Homo sapiens OX=9606 GN=SEPTIN2 PE=1 SV=1 4.51 2288 - 491570 - - - 0.5485 - 1.759 0.386 - 122.1 1 2 1 0.0011 16 0 0 0 8.62E+06 3.05E+06 - - - 4.2923 1 221125_WJC_METTL3_EV_vs_WT_F08.12001.12001.3 4.13E-10 18/68 K.QSSESAVSSTVNPVAIHK[136.11].R "sp|P10070|GLI2_HUMAN,tr|A0A7I2PJA1|A0A7I2PJA1_HUMAN" 2 1847.9469 0.001 116236 12001 3 1847.943698 616.9896 Zinc finger protein GLI2 OS=Homo sapiens OX=9606 GN=GLI2 PE=1 SV=4 6.75 2288.6 - 1.39E+06 - - - -1.7089 - 3.078 0.584 - 448 1 2 0 -0.0032 18 0 0 0 0.00E+00 2.77E+07 - - - 7.8497 0.9892 221125_WJC_METTL3_EV_vs_WT_F08.12002.12002.3 7.45E-07 17/72 S.SLVSGLNSSASEPAK[136.11]EPAK[136.11].K "sp|Q86U44|MTA70_HUMAN,tr|F5H6D8|F5H6D8_HUMAN,tr|H0YFV6|H0YFV6_HUMAN,tr|B4DTN4|B4DTN4_HUMAN" 4 1886.992 0 116237 12002 3 1886.989018 630.0046 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 5.86 2288.6 - 1.25E+07 - - - -1.592 - 3.223 0.533 - 181.6 1 1 1 -0.003 19 0 0 0 1.91E+06 9.76E+08 - - - 7.3568 0.8811 221125_WJC_METTL3_EV_vs_WT_F08.12004.12004.4 0.0177 12/108 R.GLLQDDAHPTLVTYADHSK[136.11].L "sp|Q86U44|MTA70_HUMAN,tr|F5H6D8|F5H6D8_HUMAN,tr|H0YFV6|H0YFV6_HUMAN,tr|B4DTN4|B4DTN4_HUMAN" 4 2088.0367 0.001 116239 12004 4 2089.032943 523.0165 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 5.13 2288.7 - 1.44E+06 - - - 477.1037 - 2.322 0.323 - 122.3 1 2 0 0.9962 19 0 0 0 0.00E+00 2.72E+07 - - - 2.0464 1 221125_WJC_METTL3_EV_vs_WT_F08.12011.12011.3 1.19E-07 18/64 K.QPC[160.03]PSESDIITEEDKSK.K sp|O75475|PSIP1_HUMAN 1 1961.8888 0.82 116244 12011 3 1961.890331 654.9702 PC4 and SFRS1-interacting protein OS=Homo sapiens OX=9606 GN=PSIP1 PE=1 SV=1 4.18 2289.6 - 1.13E+06 - - - 0.7794 - 3.379 0.586 - 339.6 1 2 1 0.0015 17 0 0 0 3.11E+07 3.80E+07 - - - 8.1489 1 221125_WJC_METTL3_EV_vs_WT_F08.12016.12016.3 8.77E-11 23/80 R.RPLQGVANQEPSNC[160.03]AAVAVGR.L sp|Q9UBZ4|APEX2_HUMAN 1 2193.1073 2.03 116247 12016 3 2193.098261 732.043 DNA-(apurinic or apyrimidinic site) endonuclease 2 OS=Homo sapiens OX=9606 GN=APEX2 PE=1 SV=1 8.25 2290.3 - 1.46E+06 - - - -4.1138 - 4.495 0.632 - 661.3 1 2 0 -0.009 21 0 0 0 4.60E+07 2.27E+07 - - - 9.187 1 221125_WJC_METTL3_EV_vs_WT_F08.12026.12026.3 4.98E-10 19/52 T.EC[160.03]C[160.03]HGDLLEC[160.03]ADDR.A "sp|P02768|ALBU_HUMAN,tr|B7WNR0|B7WNR0_HUMAN,tr|H0YA55|H0YA55_HUMAN,tr|A0A0C4DGB6|A0A0C4DGB6_HUMAN,tr|D6RHD5|D6RHD5_HUMAN,tr|C9JKR2|C9JKR2_HUMAN" 6 1748.6553 172.18 116253 12026 3 1748.653014 583.8924 Albumin OS=Homo sapiens OX=9606 GN=ALB PE=1 SV=2 4.1 2291.4 - 1.88E+06 - - - -1.281 - 3.143 0.785 - 587.8 1 1 0 -0.0022 14 0 0 0 5.47E+07 3.18E+05 - - - 10.3347 1 221125_WJC_METTL3_EV_vs_WT_F08.12033.12033.3 0.000105 19/52 K.DTSIQEVVSR[166.11]PSSK[136.11].R "sp|Q8IWC1|MA7D3_HUMAN,tr|A0A0A0MRP0|A0A0A0MRP0_HUMAN" 2 1549.8067 0.97 116258 12033 3 1549.804571 517.6095 MAP7 domain-containing protein 3 OS=Homo sapiens OX=9606 GN=MAP7D3 PE=1 SV=2 6.07 2292.3 - 1.63E+06 - - - -1.355 - 3.051 0.461 - 639.4 1 2 0 -0.0021 14 0 0 0 7.92E+07 8.19E+07 - - - 6.6435 0.9979 221125_WJC_METTL3_EV_vs_WT_F08.12035.12035.4 2.22E-05 18/90 R.TGVELGKPTHFTVNAK.A "sp|P21333|FLNA_HUMAN,tr|A0A7P0NMY4|A0A7P0NMY4_HUMAN,tr|Q60FE5|Q60FE5_HUMAN" 3 1697.9101 1.27 116260 12035 4 1697.907883 425.4848 Filamin-A OS=Homo sapiens OX=9606 GN=FLNA PE=1 SV=4 8.29 2292.5 - 1.82E+06 - - - -1.2881 - 3.058 0.244 - 152 1 2 0 -0.0022 16 0 0 0 1.49E+08 1.17E+08 - - - 1.7429 0.9999 221125_WJC_METTL3_EV_vs_WT_F08.12041.12041.3 6.08E-05 18/52 K.DTSIQEVVSRPSSK.R "sp|Q8IWC1|MA7D3_HUMAN,tr|A0A0A0MRP0|A0A0A0MRP0_HUMAN" 2 1531.7842 0.97 116264 12041 3 1531.780286 511.602 MAP7 domain-containing protein 3 OS=Homo sapiens OX=9606 GN=MAP7D3 PE=1 SV=2 6.07 2293.2 - 2.24E+06 - - - -2.5558 - 2.865 0.487 - 459.8 1 2 0 -0.0039 14 0 0 0 7.92E+07 8.19E+07 - - - 6.7657 0.9999 221125_WJC_METTL3_EV_vs_WT_F08.12043.12043.2 3.26E-07 28-Dec K.DSPVQSPNFQQTGSK.L "sp|Q9BYP7|WNK3_HUMAN,tr|A0A087WYK2|A0A087WYK2_HUMAN" 2 1618.7587 3.69 116266 12043 2 1618.758975 810.3866 Serine\threonine-protein kinase WNK3 OS=Homo sapiens OX=9606 GN=WNK3 PE=1 SV=3 5.84 2293.4 - 454887 - - - 0.1612 - 2.27 0.608 - 369.1 1 2 0 0.0003 15 0 0 0 1.26E+07 3.40E+06 - - - 5.5471 0.9999 221125_WJC_METTL3_EV_vs_WT_F08.12047.12047.4 6.74E-06 16/90 R.TGVELGK[136.11]PTHFTVNAK[136.11].A "sp|P21333|FLNA_HUMAN,tr|A0A7P0NMY4|A0A7P0NMY4_HUMAN,tr|Q60FE5|Q60FE5_HUMAN" 3 1713.9385 1.27 116268 12047 4 1713.936404 429.4919 Filamin-A OS=Homo sapiens OX=9606 GN=FLNA PE=1 SV=4 8.29 2293.9 - 3.52E+06 - - - -1.2054 - 2.667 0.466 - 167.9 1 2 0 -0.0021 16 0 0 0 1.48E+08 1.17E+08 - - - 3.627 1 221125_WJC_METTL3_EV_vs_WT_F08.12048.12048.3 1.37E-10 18/60 R.TGVELGK[136.11]PTHFTVNAK[136.11].A "sp|P21333|FLNA_HUMAN,tr|A0A7P0NMY4|A0A7P0NMY4_HUMAN,tr|Q60FE5|Q60FE5_HUMAN" 3 1713.9385 1.67 116269 12048 3 1713.939513 572.3201 Filamin-A OS=Homo sapiens OX=9606 GN=FLNA PE=1 SV=4 8.29 2294 - 1.72E+06 - - - 0.6085 - 3.824 0.604 - 399.3 1 2 0 0.001 16 0 0 0 1.18E+08 7.05E+07 - - - 8.7153 0.9996 221125_WJC_METTL3_EV_vs_WT_F08.12053.12053.3 0.00108 Dec-68 K.HLKPEQPADGVSAVDLEK.L sp|Q96T58|MINT_HUMAN 1 1931.9953 1.62 116274 12053 3 1931.998706 645.0057 Msx2-interacting protein OS=Homo sapiens OX=9606 GN=SPEN PE=1 SV=1 4.75 2294.6 - 549933 - - - 1.7857 - 2.154 0.365 - 123.2 1 2 0 0.0034 18 0 0 0 5.42E+06 3.34E+06 - - - 4.5192 1 221125_WJC_METTL3_EV_vs_WT_F08.12057.12057.3 3.03E-07 23/52 R.RHVFGESDELIGQK.V "sp|P60174|TPIS_HUMAN,tr|U3KPS5|U3KPS5_HUMAN,tr|U3KQF3|U3KQF3_HUMAN,tr|U3KPZ0|U3KPZ0_HUMAN" 4 1613.8162 1.12 116276 12057 3 1613.812806 538.946 Triosephosphate isomerase OS=Homo sapiens OX=9606 GN=TPI1 PE=1 SV=4 5.45 2295 - 1.83E+06 - - - -2.0839 - 4 0.648 - 924.3 1 2 0 -0.0034 14 0 0 0 2.57E+07 2.29E+07 - - - 9.4478 0.9999 221125_WJC_METTL3_EV_vs_WT_F08.12059.12059.3 2.13E-05 16/60 K.GAVLPQEISQVNQHHK.S "sp|Q8IZH2|XRN1_HUMAN,tr|H7C5E4|H7C5E4_HUMAN" 2 1783.9329 0.94 116278 12059 3 1783.935443 595.6516 5'-3' exoribonuclease 1 OS=Homo sapiens OX=9606 GN=XRN1 PE=1 SV=1 6.92 2295.2 - 759587 - - - 1.4087 - 2.737 0.452 - 245.9 1 2 0 0.0025 16 0 0 0 1.28E+07 1.36E+07 - - - 6.1621 1 221125_WJC_METTL3_EV_vs_WT_F08.12066.12066.4 0.00615 22/96 R.EGYAWAEDKEHC[160.03]EEYGR.M sp|Q9Y3I0|RTCB_HUMAN 1 2127.8592 1.21 116283 12066 4 2127.858026 532.9721 RNA-splicing ligase RtcB homolog OS=Homo sapiens OX=9606 GN=RTCB PE=1 SV=1 4.41 2295.9 - 1.75E+06 - - - -0.5672 - 3.925 0.617 - 440.7 1 2 1 -0.0012 17 0 0 0 7.03E+07 5.83E+07 - - - 5.0708 1 221125_WJC_METTL3_EV_vs_WT_F08.12073.12073.3 2.21E-07 18/60 R.TGVELGKPTHFTVNAK.A "sp|P21333|FLNA_HUMAN,tr|A0A7P0NMY4|A0A7P0NMY4_HUMAN,tr|Q60FE5|Q60FE5_HUMAN" 3 1697.9101 1.68 116287 12073 3 1697.905542 566.9773 Filamin-A OS=Homo sapiens OX=9606 GN=FLNA PE=1 SV=4 8.29 2296.8 - 4.41E+06 - - - -2.6668 - 3.837 0.574 - 425.3 1 2 0 -0.0045 16 0 0 0 1.19E+08 7.05E+07 - - - 8.3886 1 221125_WJC_METTL3_EV_vs_WT_F08.12074.12074.3 1.33E-05 14/44 R.DNIQGITKPAIR.R sp|P62805|H4_HUMAN 1 1324.7463 1.32 116288 12074 3 1324.744873 442.5894 Histone H4 OS=Homo sapiens OX=9606 GN=H4C1 PE=1 SV=2 8.75 2296.9 - 2.90E+06 - - - -1.0764 - 2.363 0.46 - 294.3 1 2 0 -0.0014 12 0 0 0 5.69E+07 4.32E+07 - - - 6.0518 1 221125_WJC_METTL3_EV_vs_WT_F08.12076.12076.3 1.39E-09 22/84 R.APR[166.11]PEAAEQVPAAGQGPGPQLR[166.11].G tr|A0A2R8Y8D9|A0A2R8Y8D9_HUMAN 1 2216.1565 5.15 116290 12076 3 2216.156798 739.7261 Proline and serine-rich protein 3 (Fragment) OS=Homo sapiens OX=9606 GN=PROSER3 PE=1 SV=1 6.19 2297.1 - 556391 - - - 0.1331 - 4.141 0.601 - 453.1 1 2 0 0.0003 22 0 0 0 3.64E+07 7.07E+06 - - - 8.6093 1 221125_WJC_METTL3_EV_vs_WT_F08.12089.12089.3 2.98 22/68 R.DAPVHGSPTGPGAWTASK[136.11].L sp|Q9BRP1|PDD2L_HUMAN 1 1742.8467 0.45 116299 12089 3 1742.843135 581.9562 Programmed cell death protein 2-like OS=Homo sapiens OX=9606 GN=PDCD2L PE=1 SV=1 6.74 2298.7 - 1.50E+06 - - - -2.073 - 3.882 0.546 - 734.8 1 2 0 -0.0036 18 0 0 0 1.60E+07 3.59E+07 - - - 8.0038 0.9998 221125_WJC_METTL3_EV_vs_WT_F08.12101.12101.4 5.83E-06 21/84 R.QASTLIDRPAPHFER.T "sp|O43491|E41L2_HUMAN,tr|A0A2R8Y5B3|A0A2R8Y5B3_HUMAN,tr|E9PII3|E9PII3_HUMAN,tr|E9PHY5|E9PHY5_HUMAN,tr|H0Y5B0|H0Y5B0_HUMAN,tr|E9PK52|E9PK52_HUMAN" 6 1736.8958 0.54 116307 12101 4 1736.894624 435.2312 Band 4.1-like protein 2 OS=Homo sapiens OX=9606 GN=EPB41L2 PE=1 SV=1 6.75 2300.1 - 1.22E+06 - - - -0.6869 - 3.089 0.382 - 483.2 1 2 0 -0.0012 15 0 0 0 9.98E+06 1.86E+07 - - - 2.9542 0.9999 221125_WJC_METTL3_EV_vs_WT_F08.12114.12114.3 7.17E-09 21/64 K.VAQPTITDNK[136.11]DGTVTVR[166.11].Y "sp|P21333|FLNA_HUMAN,tr|Q60FE5|Q60FE5_HUMAN,tr|H0Y5F3|H0Y5F3_HUMAN" 3 1831.9759 4.5 116314 12114 3 1831.972454 611.6659 Filamin-A OS=Homo sapiens OX=9606 GN=FLNA PE=1 SV=4 5.93 2301.7 - 2.23E+06 - - - -1.8597 - 3.864 0.513 - 614.1 1 2 1 -0.0034 17 0 0 0 2.30E+08 5.11E+07 - - - 7.6733 1 221125_WJC_METTL3_EV_vs_WT_F08.12120.12120.3 1.09E-07 19/48 R.GEC[160.03]QAC[160.03]DQLHFC[160.03]R[166.11].R sp|Q96H79|ZCCHL_HUMAN 1 1689.6686 1.04 116317 12120 3 1689.66395 564.2301 Zinc finger CCCH-type antiviral protein 1-like OS=Homo sapiens OX=9606 GN=ZC3HAV1L PE=1 SV=2 5.32 2302.4 - 1.09E+06 - - - -2.7224 - 3.409 0.682 - 746 1 2 0 -0.0046 13 0 0 0 2.49E+07 2.38E+07 - - - 9.4675 1 221125_WJC_METTL3_EV_vs_WT_F08.12124.12124.3 3.22E-08 15/44 R.TAAENDFVTLKK.D sp|P35908|K22E_HUMAN 1 1335.7034 224.09 116318 12124 3 1335.69969 446.2418 "Keratin, type II cytoskeletal 2 epidermal OS=Homo sapiens OX=9606 GN=KRT2 PE=1 SV=2" 5.73 2303.1 - 1.35E+06 - - - -2.8008 - 2.488 0.623 - 284 1 2 0 -0.0037 12 0 0 0 4.78E+07 2.13E+05 - - - 8.0113 0.9999 221125_WJC_METTL3_EV_vs_WT_F08.12128.12128.3 4.10E-06 16/52 K.TKLEQLHIMQEQQK.S "sp|Q6P3W7|SCYL2_HUMAN,tr|F8VSC5|F8VSC5_HUMAN,tr|A0A0U1RQQ9|A0A0U1RQQ9_HUMAN" 3 1752.9193 1.7 116319 12128 3 1752.916709 585.3137 SCY1-like protein 2 OS=Homo sapiens OX=9606 GN=SCYL2 PE=1 SV=1 6.42 2303.6 - 1.49E+06 - - - -1.4519 - 2.909 0.485 - 202.2 1 2 1 -0.0025 14 0 0 0 5.00E+07 2.94E+07 - - - 6.7843 1 221125_WJC_METTL3_EV_vs_WT_F08.12137.12137.3 4.77E-08 14/48 R.GEC[160.03]QAC[160.03]DQLHFC[160.03]R.R sp|Q96H79|ZCCHL_HUMAN 1 1679.6603 1.04 116323 12137 3 1679.659961 560.894 Zinc finger CCCH-type antiviral protein 1-like OS=Homo sapiens OX=9606 GN=ZC3HAV1L PE=1 SV=2 5.32 2304.6 - 2.04E+06 - - - -0.1899 - 2.551 0.622 - 265.8 1 2 0 -0.0003 13 0 0 0 2.49E+07 2.38E+07 - - - 8.0137 0.7725 221125_WJC_METTL3_EV_vs_WT_F08.12141.12141.3 0.169 Nov-52 R.KIELFGR[166.11]PHNVQPN.W sp|Q86U44|MTA70_HUMAN 1 1657.8928 - 116326 12141 3 1657.890007 553.6382 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 8.75 2305 - 2.93E+06 - - - -1.681 - 2.07 0.214 - 108.7 1 1 0 -0.0028 14 0 0 0 - - - - - 2.8586 1 221125_WJC_METTL3_EV_vs_WT_F08.12143.12143.3 7.51E-06 17/60 K.GHGEC[160.03]PTTENTETFIR.L sp|O60942|MCE1_HUMAN 1 1847.8108 1.14 116328 12143 3 1847.810952 616.9442 mRNA-capping enzyme OS=Homo sapiens OX=9606 GN=RNGTT PE=1 SV=1 4.75 2305.3 - 672609 - - - 0.0682 - 3.644 0.615 - 523.6 1 2 0 0.0001 16 0 0 0 1.64E+07 1.44E+07 - - - 8.7145 1 221125_WJC_METTL3_EV_vs_WT_F08.12148.12148.2 1.01E-09 20/40 F.ASSLVSGLNSSASEPAK[136.11]EPAK[136.11].K "sp|Q86U44|MTA70_HUMAN,tr|F5H6D8|F5H6D8_HUMAN,tr|H0YFV6|H0YFV6_HUMAN,tr|B4DTN4|B4DTN4_HUMAN" 4 2045.0612 0.001 116331 12148 2 2045.053074 1023.5379 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 6.19 2305.9 - 4.71E+06 - - - -3.9559 - 4.027 0.667 - 1026.4 1 1 1 -0.0081 21 0 0 0 0.00E+00 2.66E+08 - - - 7.3897 0.9999 221125_WJC_METTL3_EV_vs_WT_F08.12154.12154.4 2.97E-10 27/90 K.IFVGGIK[136.11]EDTEEHHLR[166.11].D "sp|Q32P51|RA1L2_HUMAN,sp|P09651|ROA1_HUMAN,sp|P22626|ROA2_HUMAN,tr|A0A7I2YQN4|A0A7I2YQN4_HUMAN,tr|A0A7I2YQX9|A0A7I2YQX9_HUMAN,tr|A0A7I2V4N0|A0A7I2V4N0_HUMAN,tr|A0A024RA28|A0A024RA28_HUMAN,tr|A0A7I2V4N1|A0A7I2V4N1_HUMAN,tr|A0A7I2V4I6|A0A7I2V4I6_HUMAN,tr|F8VZ49|F8VZ49_HUMAN,tr|A0A7I2V3R8|A0A7I2V3R8_HUMAN,tr|A0A087WUI2|A0A087WUI2_HUMAN,tr|A0A7I2V4S4|A0A7I2V4S4_HUMAN,tr|F8VTQ5|F8VTQ5_HUMAN,tr|F8W6I7|F8W6I7_HUMAN,tr|A0A7I2V2L6|A0A7I2V2L6_HUMAN,tr|A0A7I2V323|A0A7I2V323_HUMAN,tr|A0A7I2V3W0|A0A7I2V3W0_HUMAN,tr|A0A7I2V5U9|A0A7I2V5U9_HUMAN,tr|A0A2R8Y4L2|A0A2R8Y4L2_HUMAN,tr|A0A7I2V3P1|A0A7I2V3P1_HUMAN,tr|A0A7I2V3P7|A0A7I2V3P7_HUMAN" 22 1896.9813 1.34 116334 12154 4 1896.976719 475.2526 Heterogeneous nuclear ribonucleoprotein A1-like 2 OS=Homo sapiens OX=9606 GN=HNRNPA1L2 PE=2 SV=2 5.36 2306.7 - 2.10E+06 - - - -2.4049 - 4.368 0.579 - 659.7 1 2 1 -0.0046 16 0 0 0 7.11E+08 5.29E+08 - - - 4.7837 0.9229 221125_WJC_METTL3_EV_vs_WT_F08.12158.12158.4 1.24E-05 21/120 F.ASSLVSGLNSSASEPAK[136.11]EPAK[136.11].K "sp|Q86U44|MTA70_HUMAN,tr|F5H6D8|F5H6D8_HUMAN,tr|H0YFV6|H0YFV6_HUMAN,tr|B4DTN4|B4DTN4_HUMAN" 4 2045.0612 0.02 116336 12158 4 2045.05512 512.2726 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 6.19 2307.2 - 2.24E+06 - - - -2.9554 - 3.627 0.445 - 374.2 1 1 1 -0.006 21 0 0 0 1.58E+06 6.38E+07 - - - 3.5236 0.9999 221125_WJC_METTL3_EV_vs_WT_F08.12161.12161.3 4.56E-07 17/52 K.TK[136.11]LEQLHIMQEQQK[136.11].S "sp|Q6P3W7|SCYL2_HUMAN,tr|F8VSC5|F8VSC5_HUMAN,tr|A0A0U1RQQ9|A0A0U1RQQ9_HUMAN" 3 1768.9477 1.7 116339 12161 3 1768.944895 590.6565 SCY1-like protein 2 OS=Homo sapiens OX=9606 GN=SCYL2 PE=1 SV=1 6.42 2307.5 - 2.10E+06 - - - -1.5597 - 3.005 0.478 - 199.9 1 2 1 -0.0028 14 0 0 0 5.00E+07 2.94E+07 - - - 6.7925 0.9843 221125_WJC_METTL3_EV_vs_WT_F08.12168.12168.2 1.65 22-Jul R.K[136.11]LEEDLLVEVSR.Y sp|Q9Y259|CHKB_HUMAN 1 1436.7966 - 116344 12168 2 1436.798208 719.4056 Choline\ethanolamine kinase OS=Homo sapiens OX=9606 GN=CHKB PE=1 SV=3 4.41 2308.1 - 9.70E+06 - - - 1.1122 - 1.452 0.112 - 115.9 5 2 0 0.0016 12 0 0 0 - - - - - 0.5368 1 221125_WJC_METTL3_EV_vs_WT_F08.12170.12170.3 8.63E-08 20/60 K.IFVGGIKEDTEEHHLR.D "sp|Q32P51|RA1L2_HUMAN,sp|P09651|ROA1_HUMAN,sp|P22626|ROA2_HUMAN,tr|A0A7I2YQN4|A0A7I2YQN4_HUMAN,tr|A0A7I2YQX9|A0A7I2YQX9_HUMAN,tr|A0A7I2V4N0|A0A7I2V4N0_HUMAN,tr|A0A024RA28|A0A024RA28_HUMAN,tr|A0A7I2V4N1|A0A7I2V4N1_HUMAN,tr|A0A7I2V4I6|A0A7I2V4I6_HUMAN,tr|F8VZ49|F8VZ49_HUMAN,tr|A0A7I2V3R8|A0A7I2V3R8_HUMAN,tr|A0A087WUI2|A0A087WUI2_HUMAN,tr|A0A7I2V4S4|A0A7I2V4S4_HUMAN,tr|F8VTQ5|F8VTQ5_HUMAN,tr|F8W6I7|F8W6I7_HUMAN,tr|A0A7I2V2L6|A0A7I2V2L6_HUMAN,tr|A0A7I2V323|A0A7I2V323_HUMAN,tr|A0A7I2V3W0|A0A7I2V3W0_HUMAN,tr|A0A7I2V5U9|A0A7I2V5U9_HUMAN,tr|A0A2R8Y4L2|A0A2R8Y4L2_HUMAN,tr|A0A7I2V3P1|A0A7I2V3P1_HUMAN,tr|A0A7I2V3P7|A0A7I2V3P7_HUMAN" 22 1878.9588 1.3 116346 12170 3 1878.956055 627.3269 Heterogeneous nuclear ribonucleoprotein A1-like 2 OS=Homo sapiens OX=9606 GN=HNRNPA1L2 PE=2 SV=2 5.36 2308.3 - 2.54E+06 - - - -1.4668 - 3.446 0.609 - 487.6 1 2 1 -0.0028 16 0 0 0 2.30E+08 1.77E+08 - - - 8.5035 0.9998 221125_WJC_METTL3_EV_vs_WT_F08.12173.12173.4 2.85E-10 23/90 K.IFVGGIKEDTEEHHLR.D "sp|Q32P51|RA1L2_HUMAN,sp|P09651|ROA1_HUMAN,sp|P22626|ROA2_HUMAN,tr|A0A7I2YQN4|A0A7I2YQN4_HUMAN,tr|A0A7I2YQX9|A0A7I2YQX9_HUMAN,tr|A0A7I2V4N0|A0A7I2V4N0_HUMAN,tr|A0A024RA28|A0A024RA28_HUMAN,tr|A0A7I2V4N1|A0A7I2V4N1_HUMAN,tr|A0A7I2V4I6|A0A7I2V4I6_HUMAN,tr|F8VZ49|F8VZ49_HUMAN,tr|A0A7I2V3R8|A0A7I2V3R8_HUMAN,tr|A0A087WUI2|A0A087WUI2_HUMAN,tr|A0A7I2V4S4|A0A7I2V4S4_HUMAN,tr|F8VTQ5|F8VTQ5_HUMAN,tr|F8W6I7|F8W6I7_HUMAN,tr|A0A7I2V2L6|A0A7I2V2L6_HUMAN,tr|A0A7I2V323|A0A7I2V323_HUMAN,tr|A0A7I2V3W0|A0A7I2V3W0_HUMAN,tr|A0A7I2V5U9|A0A7I2V5U9_HUMAN,tr|A0A2R8Y4L2|A0A2R8Y4L2_HUMAN,tr|A0A7I2V3P1|A0A7I2V3P1_HUMAN,tr|A0A7I2V3P7|A0A7I2V3P7_HUMAN" 22 1878.9588 1.34 116347 12173 4 1878.953346 470.747 Heterogeneous nuclear ribonucleoprotein A1-like 2 OS=Homo sapiens OX=9606 GN=HNRNPA1L2 PE=2 SV=2 5.36 2308.7 - 1.24E+07 - - - -2.9085 - 4.148 0.553 - 460.3 1 2 1 -0.0055 16 0 0 0 7.11E+08 5.29E+08 - - - 4.5389 1 221125_WJC_METTL3_EV_vs_WT_F08.12179.12179.3 7.95E-13 30/60 K.IFVGGIK[136.11]EDTEEHHLR[166.11].D "sp|Q32P51|RA1L2_HUMAN,sp|P09651|ROA1_HUMAN,sp|P22626|ROA2_HUMAN,tr|A0A7I2YQN4|A0A7I2YQN4_HUMAN,tr|A0A7I2YQX9|A0A7I2YQX9_HUMAN,tr|A0A7I2V4N0|A0A7I2V4N0_HUMAN,tr|A0A024RA28|A0A024RA28_HUMAN,tr|A0A7I2V4N1|A0A7I2V4N1_HUMAN,tr|A0A7I2V4I6|A0A7I2V4I6_HUMAN,tr|F8VZ49|F8VZ49_HUMAN,tr|A0A7I2V3R8|A0A7I2V3R8_HUMAN,tr|A0A087WUI2|A0A087WUI2_HUMAN,tr|A0A7I2V4S4|A0A7I2V4S4_HUMAN,tr|F8VTQ5|F8VTQ5_HUMAN,tr|F8W6I7|F8W6I7_HUMAN,tr|A0A7I2V2L6|A0A7I2V2L6_HUMAN,tr|A0A7I2V323|A0A7I2V323_HUMAN,tr|A0A7I2V3W0|A0A7I2V3W0_HUMAN,tr|A0A7I2V5U9|A0A7I2V5U9_HUMAN,tr|A0A2R8Y4L2|A0A2R8Y4L2_HUMAN,tr|A0A7I2V3P1|A0A7I2V3P1_HUMAN,tr|A0A7I2V3P7|A0A7I2V3P7_HUMAN" 22 1896.9813 1.3 116353 12179 3 1896.976517 633.3344 Heterogeneous nuclear ribonucleoprotein A1-like 2 OS=Homo sapiens OX=9606 GN=HNRNPA1L2 PE=2 SV=2 5.36 2309.1 - 2.46E+06 - - - -2.5114 - 4.039 0.642 - 1377.5 1 2 1 -0.0048 16 0 0 0 2.30E+08 1.77E+08 - - - 9.2783 1 221125_WJC_METTL3_EV_vs_WT_F08.12185.12185.2 2.56E-07 18/26 R.KIELFGR[166.11]PHNVQPN.W sp|Q86U44|MTA70_HUMAN 1 1657.8928 - 116357 12185 2 1657.890489 829.9537 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 8.75 2309.8 - 2.41E+06 - - - -1.3903 - 2.953 0.573 - 636.7 1 1 0 -0.0023 14 0 0 0 - - - - - 5.9897 0.9994 221125_WJC_METTL3_EV_vs_WT_F08.12190.12190.3 0.00181 15/68 K.IGAQSHGDNSC[160.03]GIEIVC[160.03]K[136.11].D "sp|Q13613|MTMR1_HUMAN,tr|E9PIH9|E9PIH9_HUMAN,tr|Q8NEC6|Q8NEC6_HUMAN,tr|F8WA39|F8WA39_HUMAN,tr|F8W8S8|F8W8S8_HUMAN,tr|H0YDX3|H0YDX3_HUMAN,tr|F8W764|F8W764_HUMAN" 7 1951.8971 0.14 116359 12190 3 1951.889725 651.6397 Myotubularin-related protein 1 OS=Homo sapiens OX=9606 GN=MTMR1 PE=1 SV=4 5.32 2310.4 - 2.04E+06 - - - -3.8019 - 2.184 0.427 - 175 1 2 0 -0.0074 18 0 0 0 6.71E+06 4.69E+07 - - - 5.2437 1 221125_WJC_METTL3_EV_vs_WT_F08.12201.12201.3 5.47E-12 17/52 R.HHC[160.03]PNTPIILVGTK.L sp|P63000|RAC1_HUMAN 1 1585.8399 0.97 116366 12201 3 1585.837184 529.6206 Ras-related C3 botulinum toxin substrate 1 OS=Homo sapiens OX=9606 GN=RAC1 PE=1 SV=1 8.24 2311.6 - 2.10E+06 - - - -1.7013 - 3.132 0.673 - 621.4 1 2 0 -0.0027 14 0 0 0 1.01E+08 1.04E+08 - - - 9.0766 0.9825 221125_WJC_METTL3_EV_vs_WT_F08.12203.12203.3 2.98E-08 21/80 F.ASSLVSGLNSSASEPAK[136.11]EPAK[136.11].K "sp|Q86U44|MTA70_HUMAN,tr|F5H6D8|F5H6D8_HUMAN,tr|H0YFV6|H0YFV6_HUMAN,tr|B4DTN4|B4DTN4_HUMAN" 4 2045.0612 0 116367 12203 3 2045.055313 682.6943 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 6.19 2311.8 - 1.56E+08 - - - -2.861 - 3.881 0.566 - 525.9 1 1 1 -0.0059 21 0 0 0 3.61E+07 7.77E+09 - - - 8.0999 1 221125_WJC_METTL3_EV_vs_WT_F08.12213.12213.3 1.92E-11 24/64 R.FTNANFQEVSAHTSSGK.D "sp|P55197|AF10_HUMAN,tr|Q5JT35|Q5JT35_HUMAN" 2 1823.8438 7.33 116372 12213 3 1823.841192 608.9552 Protein AF-10 OS=Homo sapiens OX=9606 GN=MLLT10 PE=1 SV=2 6.75 2313 - 4.98E+06 - - - -1.4524 - 3.869 0.633 - 730.8 1 2 0 -0.0026 17 0 0 0 1.58E+08 2.15E+07 - - - 9.0147 0.9998 221125_WJC_METTL3_EV_vs_WT_F08.12215.12215.3 1.61E-05 18/48 R.KTEELEEESFPER.S "sp|Q9Y2W1|TR150_HUMAN,tr|A0A3B3ITZ9|A0A3B3ITZ9_HUMAN" 2 1621.7471 3.08 116374 12215 3 1621.742222 541.5897 Thyroid hormone receptor-associated protein 3 OS=Homo sapiens OX=9606 GN=THRAP3 PE=1 SV=2 4.21 2313.2 - 2.05E+06 - - - -3.0362 - 3.116 0.403 - 608.3 1 2 0 -0.0049 13 0 0 0 1.16E+09 3.77E+08 - - - 6.1132 1 221125_WJC_METTL3_EV_vs_WT_F08.12226.12226.3 6.13E-09 17/52 R.HHC[160.03]PNTPIILVGTK[136.11].L sp|P63000|RAC1_HUMAN 1 1593.8541 1.08 116378 12226 3 1593.854779 532.292 Ras-related C3 botulinum toxin substrate 1 OS=Homo sapiens OX=9606 GN=RAC1 PE=1 SV=1 8.24 2314.7 - 1.61E+06 - - - 0.4373 - 3.137 0.636 - 466 1 2 0 0.0007 14 0 0 0 7.18E+07 6.68E+07 - - - 8.6688 1 221125_WJC_METTL3_EV_vs_WT_F08.12235.12235.3 0.000265 18/48 R.K[136.11]TEELEEESFPER[166.11].S "sp|Q9Y2W1|TR150_HUMAN,tr|A0A3B3ITZ9|A0A3B3ITZ9_HUMAN" 2 1639.7696 3.1 116383 12235 3 1639.770173 547.5971 Thyroid hormone receptor-associated protein 3 OS=Homo sapiens OX=9606 GN=THRAP3 PE=1 SV=2 4.21 2315.9 - 2.81E+06 - - - 0.3397 - 2.924 0.466 - 506.5 1 2 0 0.0006 13 0 0 0 1.17E+09 3.78E+08 - - - 6.6444 0.9998 221125_WJC_METTL3_EV_vs_WT_F08.12245.12245.3 7.89E-06 16/48 R.TNEKVELQELNDR.F "sp|P08670|VIME_HUMAN,sp|P17661|DESM_HUMAN,tr|B0YJC4|B0YJC4_HUMAN,tr|A0A1B0GTT5|A0A1B0GTT5_HUMAN" 4 1586.79 1.93 116389 12245 3 1586.78664 529.9373 Vimentin OS=Homo sapiens OX=9606 GN=VIM PE=1 SV=4 4.41 2317 - 3.88E+06 - - - -2.1263 - 3.113 0.459 - 460 1 2 1 -0.0034 13 0 0 0 4.34E+08 2.25E+08 - - - 6.7354 0.9999 221125_WJC_METTL3_EV_vs_WT_F08.12247.12247.3 8.78E-07 19/48 R.TNEK[136.11]VELQELNDR[166.11].F "sp|P08670|VIME_HUMAN,sp|P17661|DESM_HUMAN,tr|B0YJC4|B0YJC4_HUMAN,tr|A0A1B0GTT5|A0A1B0GTT5_HUMAN" 4 1604.8125 1.93 116391 12247 3 1604.813286 535.9448 Vimentin OS=Homo sapiens OX=9606 GN=VIM PE=1 SV=4 4.41 2317.2 - 2.10E+06 - - - 0.4997 - 3.25 0.503 - 707.7 1 2 1 0.0008 13 0 0 0 4.34E+08 2.25E+08 - - - 7.3434 1 221125_WJC_METTL3_EV_vs_WT_F08.12257.12257.3 4.23E-08 19/84 R.SAATSGAGSTTSGVVSGSLGSR[166.11].E sp|Q7Z6Z7|HUWE1_HUMAN 1 1905.9267 0.28 116397 12257 3 1905.925419 636.3162 E3 ubiquitin-protein ligase HUWE1 OS=Homo sapiens OX=9606 GN=HUWE1 PE=1 SV=3 9.47 2318.4 - 1.83E+06 - - - -0.6889 - 3.628 0.571 - 317.1 1 2 0 -0.0013 22 0 0 0 6.96E+06 2.47E+07 - - - 7.961 1 221125_WJC_METTL3_EV_vs_WT_F08.12272.12272.3 4.13E-07 24/76 K.NQAAIQGR[166.11]PPYAASAEEVAK[136.11].E "sp|Q9NZB2|F120A_HUMAN,tr|A0A0C4DG79|A0A0C4DG79_HUMAN,tr|A0A494C0Y9|A0A494C0Y9_HUMAN" 3 2088.0719 2.18 116406 12272 3 2088.071007 697.0312 Constitutive coactivator of PPAR-gamma-like protein 1 OS=Homo sapiens OX=9606 GN=FAM120A PE=1 SV=2 6.14 2320.2 - 1.58E+06 - - - -0.4214 - 3.855 0.421 - 710.2 1 2 0 -0.0009 20 0 0 0 5.27E+07 2.42E+07 - - - 6.5071 1 221125_WJC_METTL3_EV_vs_WT_F08.12275.12275.2 5.13E-06 14/24 R.TNEK[136.11]VELQELNDR[166.11].F "sp|P08670|VIME_HUMAN,sp|P17661|DESM_HUMAN,tr|B0YJC4|B0YJC4_HUMAN,tr|A0A1B0GTT5|A0A1B0GTT5_HUMAN" 4 1604.8125 2.92 116409 12275 2 1604.80801 803.4135 Vimentin OS=Homo sapiens OX=9606 GN=VIM PE=1 SV=4 4.41 2320.6 - 710177 - - - -2.7879 - 3.058 0.601 - 798.1 1 2 1 -0.0045 13 0 0 0 3.76E+07 1.29E+07 - - - 6.3473 1 221125_WJC_METTL3_EV_vs_WT_F08.12279.12279.2 2.41E-07 15/24 R.TNEKVELQELNDR.F "sp|P08670|VIME_HUMAN,sp|P17661|DESM_HUMAN,tr|B0YJC4|B0YJC4_HUMAN,tr|A0A1B0GTT5|A0A1B0GTT5_HUMAN" 4 1586.79 2.99 116411 12279 2 1586.790112 794.4023 Vimentin OS=Homo sapiens OX=9606 GN=VIM PE=1 SV=4 4.41 2321.1 - 1.49E+06 - - - 0.0618 - 3.134 0.525 - 821.6 1 2 1 0.0001 13 0 0 0 3.86E+07 1.29E+07 - - - 5.8504 1 221125_WJC_METTL3_EV_vs_WT_F08.12282.12282.2 1.58E-07 13/24 R.TNEK[136.11]VELQELNDR[166.11].F "sp|P08670|VIME_HUMAN,sp|P17661|DESM_HUMAN,tr|B0YJC4|B0YJC4_HUMAN,tr|A0A1B0GTT5|A0A1B0GTT5_HUMAN" 4 1604.8125 2.92 116414 12282 2 1604.812303 803.4135 Vimentin OS=Homo sapiens OX=9606 GN=VIM PE=1 SV=4 4.41 2321.4 - 870565 - - - -0.1128 - 2.979 0.602 - 698.8 1 2 1 -0.0002 13 0 0 0 3.76E+07 1.29E+07 - - - 6.2889 1 221125_WJC_METTL3_EV_vs_WT_F08.12287.12287.2 6.84E-08 16/24 R.KTEELEEESFPER.S "sp|Q9Y2W1|TR150_HUMAN,tr|A0A3B3ITZ9|A0A3B3ITZ9_HUMAN" 2 1621.7471 3.69 116417 12287 2 1621.747293 811.8808 Thyroid hormone receptor-associated protein 3 OS=Homo sapiens OX=9606 GN=THRAP3 PE=1 SV=2 4.21 2322.1 - 2.27E+06 - - - 0.0906 - 3.701 0.637 - 1105.8 1 2 0 0.0001 13 0 0 0 1.27E+08 3.44E+07 - - - 7.1044 0.9998 221125_WJC_METTL3_EV_vs_WT_F08.12296.12296.4 0.00235 15/78 K.K[136.11]GFDQEEVFEK[136.11]PTR[166.11].E "sp|P30876|RPB2_HUMAN,tr|C9J4M6|C9J4M6_HUMAN,tr|C9J2Y9|C9J2Y9_HUMAN" 3 1734.8787 0.52 116422 12296 4 1734.874616 434.727 DNA-directed RNA polymerase II subunit RPB2 OS=Homo sapiens OX=9606 GN=POLR2B PE=1 SV=1 4.87 2323.2 - 586831 - - - -2.3656 - 2.725 0.419 - 167.8 1 2 0 -0.0041 14 0 0 0 1.59E+07 3.03E+07 - - - 3.2367 0.9999 221125_WJC_METTL3_EV_vs_WT_F08.12301.12301.4 6.54E-05 22/108 K.GSEPRPLVPPVSGHATIAR.T "sp|Q9Y618|NCOR2_HUMAN,tr|C9J7T7|C9J7T7_HUMAN,tr|C9JE98|C9JE98_HUMAN,tr|C9J0Q5|C9J0Q5_HUMAN,tr|A0A384DVL6|A0A384DVL6_HUMAN" 5 1940.0592 3.14 116427 12301 4 1940.054951 486.0221 Nuclear receptor corepressor 2 OS=Homo sapiens OX=9606 GN=NCOR2 PE=1 SV=3 9.61 2323.8 - 603947 - - - -2.187 - 3.975 0.452 - 528.6 1 2 0 -0.0042 19 0 0 0 3.28E+07 1.04E+07 - - - 3.6259 0.9965 221125_WJC_METTL3_EV_vs_WT_F08.12305.12305.3 0.0327 15/52 R.HLQLAIRNDEELNK.L "sp|P16104|H2AX_HUMAN,sp|Q9BTM1|H2AJ_HUMAN,sp|Q93077|H2A1C_HUMAN,sp|Q99878|H2A1J_HUMAN,sp|Q16777|H2A2C_HUMAN,sp|Q96QV6|H2A1A_HUMAN,sp|P04908|H2A1B_HUMAN,sp|P20671|H2A1D_HUMAN,sp|P0C0S8|H2A1_HUMAN,sp|Q6FI13|H2A2A_HUMAN,sp|Q96KK5|H2A1H_HUMAN,sp|Q7L7L0|H2A3_HUMAN,tr|A0A0U1RR32|A0A0U1RR32_HUMAN,tr|A0A0U1RRH7|A0A0U1RRH7_HUMAN,tr|A0A3B3IS11|A0A3B3IS11_HUMAN,tr|H0YFX9|H0YFX9_HUMAN" 16 1691.8955 1.72 116429 12305 3 1691.892045 564.9724 Histone H2AX OS=Homo sapiens OX=9606 GN=H2AX PE=1 SV=2 5.45 2324.2 - 1.85E+06 - - - -2.0314 - 2.453 0.274 - 238 1 2 1 -0.0034 14 0 0 0 7.02E+07 4.07E+07 - - - 3.9785 0.9999 221125_WJC_METTL3_EV_vs_WT_F08.12306.12306.3 1.04E-06 16/52 R.IVDDLK[136.11]DEAEQYR[166.11]K[136.11].M sp|O75533|SF3B1_HUMAN 1 1746.8998 0.35 116430 12306 3 1746.896225 583.3072 Splicing factor 3B subunit 1 OS=Homo sapiens OX=9606 GN=SF3B1 PE=1 SV=3 4.44 2324.4 - 1.84E+06 - - - -2.0745 - 3.032 0.55 - 328.9 1 2 1 -0.0036 14 0 0 0 3.23E+07 9.21E+07 - - - 7.6187 0.9999 221125_WJC_METTL3_EV_vs_WT_F08.12307.12307.3 3.58E-07 20/48 K.NKFDVDAADEKFR.R sp|Q9H0D6|XRN2_HUMAN 1 1553.7474 1.01 116431 12307 3 1553.748136 518.9231 5'-3' exoribonuclease 2 OS=Homo sapiens OX=9606 GN=XRN2 PE=1 SV=1 4.68 2324.5 - 1.27E+06 - - - 0.4602 - 3.365 0.56 - 568 1 2 2 0.0007 13 0 0 0 7.49E+07 7.40E+07 - - - 8.0732 1 221125_WJC_METTL3_EV_vs_WT_F08.12310.12310.3 1.53E-07 26/48 K.NK[136.11]FDVDAADEK[136.11]FR[166.11].R sp|Q9H0D6|XRN2_HUMAN 1 1579.7841 1.01 116432 12310 3 1579.781356 527.602 5'-3' exoribonuclease 2 OS=Homo sapiens OX=9606 GN=XRN2 PE=1 SV=1 4.68 2324.9 - 1.74E+06 - - - -1.7312 - 4.081 0.59 - 1140.1 1 2 2 -0.0027 13 0 0 0 7.49E+07 7.41E+07 - - - 8.9302 0.9999 221125_WJC_METTL3_EV_vs_WT_F08.12312.12312.3 3.40E-05 16/68 K.AAVHTYGIASVPNQPLKK.Q "sp|Q9UHI6|DDX20_HUMAN,tr|A0A7P0T9T8|A0A7P0T9T8_HUMAN" 2 1893.0472 1.1 116433 12312 3 1893.051007 632.023 Probable ATP-dependent RNA helicase DDX20 OS=Homo sapiens OX=9606 GN=DDX20 PE=1 SV=2 9.7 2325.1 - 658676 - - - 1.9941 - 2.557 0.493 - 237.2 1 2 0 0.0038 18 0 0 0 1.31E+07 1.19E+07 - - - 6.3732 0.9996 221125_WJC_METTL3_EV_vs_WT_F08.12316.12316.4 1.19E-06 23/114 K.QSAQLTALAAQQQAAGK[136.11]EEK[136.11].S sp|Q96A49|SYAP1_HUMAN 1 2086.0989 1.5 116435 12316 4 2086.098545 522.532 Synapse-associated protein 1 OS=Homo sapiens OX=9606 GN=SYAP1 PE=1 SV=1 6.14 2325.5 - 1.60E+06 - - - -0.1922 - 4.312 0.406 - 553.2 1 2 1 -0.0004 20 0 0 0 1.46E+08 9.71E+07 - - - 3.2483 1 221125_WJC_METTL3_EV_vs_WT_F08.12317.12317.3 4.86E-11 21/52 K.K[136.11]GFDQEEVFEK[136.11]PTR[166.11].E "sp|P30876|RPB2_HUMAN,tr|C9J4M6|C9J4M6_HUMAN,tr|C9J2Y9|C9J2Y9_HUMAN" 3 1734.8787 1.09 116436 12317 3 1734.876786 579.3002 DNA-directed RNA polymerase II subunit RPB2 OS=Homo sapiens OX=9606 GN=POLR2B PE=1 SV=1 4.87 2325.6 - 1.62E+06 - - - -1.1148 - 3.534 0.645 - 670.6 1 2 0 -0.0019 14 0 0 0 3.03E+07 2.78E+07 - - - 9.0855 0.9999 221125_WJC_METTL3_EV_vs_WT_F08.12320.12320.4 2.63E-06 18/72 K.NKFDVDAADEKFR.R sp|Q9H0D6|XRN2_HUMAN 1 1553.7474 1.08 116439 12320 4 1553.745875 389.4441 5'-3' exoribonuclease 2 OS=Homo sapiens OX=9606 GN=XRN2 PE=1 SV=1 4.68 2325.9 - 997088 - - - -0.995 - 3.29 0.554 - 448.8 1 2 2 -0.0015 13 0 0 0 3.82E+07 3.53E+07 - - - 4.4891 0.9991 221125_WJC_METTL3_EV_vs_WT_F08.12324.12324.4 5.97E-05 23/114 K.QSAQLTALAAQQQAAGKEEK.S sp|Q96A49|SYAP1_HUMAN 1 2070.0705 1.5 116441 12324 4 2070.07232 518.5249 Synapse-associated protein 1 OS=Homo sapiens OX=9606 GN=SYAP1 PE=1 SV=1 6.14 2326.4 - 4.05E+06 - - - 0.857 - 3.802 0.356 - 551.7 1 2 1 0.0018 20 0 0 0 1.46E+08 9.71E+07 - - - 2.7706 0.9997 221125_WJC_METTL3_EV_vs_WT_F08.12326.12326.4 3.24E-06 18/72 K.NK[136.11]FDVDAADEK[136.11]FR[166.11].R sp|Q9H0D6|XRN2_HUMAN 1 1579.7841 1.08 116443 12326 4 1579.781969 395.9533 5'-3' exoribonuclease 2 OS=Homo sapiens OX=9606 GN=XRN2 PE=1 SV=1 4.68 2326.6 - 1.99E+06 - - - -1.3432 - 3.308 0.432 - 482.7 1 2 2 -0.0021 13 0 0 0 3.82E+07 3.53E+07 - - - 3.4291 0.9999 221125_WJC_METTL3_EV_vs_WT_F08.12327.12327.3 0.000894 17/72 K.GSEPRPLVPPVSGHATIAR.T "sp|Q9Y618|NCOR2_HUMAN,tr|C9J7T7|C9J7T7_HUMAN,tr|C9JE98|C9JE98_HUMAN,tr|C9J0Q5|C9J0Q5_HUMAN,tr|A0A384DVL6|A0A384DVL6_HUMAN" 5 1940.0592 2.06 116444 12327 3 1940.057138 647.6937 Nuclear receptor corepressor 2 OS=Homo sapiens OX=9606 GN=NCOR2 PE=1 SV=3 9.61 2326.7 - 558981 - - - -1.0598 - 2.894 0.395 - 244.1 1 2 0 -0.0021 19 0 0 0 8.81E+06 4.27E+06 - - - 5.554 1 221125_WJC_METTL3_EV_vs_WT_F08.12330.12330.2 4.92E-09 15/26 R.K[136.11]IELFGR[166.11]PHNVQPN.W sp|Q86U44|MTA70_HUMAN 1 1665.907 0.001 116446 12330 2 1665.905174 833.9608 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 8.75 2327 - 1.17E+07 - - - -1.0925 - 2.9 0.601 - 473.2 1 1 0 -0.0018 14 0 0 0 0.00E+00 6.45E+09 - - - 6.1513 0.9998 221125_WJC_METTL3_EV_vs_WT_F08.12332.12332.4 2.44E-08 19/78 R.IVDDLK[136.11]DEAEQYR[166.11]K[136.11].M sp|O75533|SF3B1_HUMAN 1 1746.8998 0.39 116447 12332 4 1746.895695 437.7322 Splicing factor 3B subunit 1 OS=Homo sapiens OX=9606 GN=SF3B1 PE=1 SV=3 4.44 2327.2 - 3.01E+06 - - - -2.3779 - 3.706 0.514 - 216.2 1 2 1 -0.0042 14 0 0 0 1.96E+07 5.05E+07 - - - 4.1755 1 221125_WJC_METTL3_EV_vs_WT_F08.12333.12333.2 7.77E-15 23/38 K.QSAQLTALAAQQQAAGK[136.11]EEK[136.11].S sp|Q96A49|SYAP1_HUMAN 1 2086.0989 1.38 116448 12333 2 2086.093693 1044.0567 Synapse-associated protein 1 OS=Homo sapiens OX=9606 GN=SYAP1 PE=1 SV=1 6.14 2327.3 - 2.06E+06 - - - -2.5181 - 4.481 0.692 - 1846.5 1 2 1 -0.0053 20 0 0 0 1.48E+08 1.07E+08 - - - 7.8379 1 221125_WJC_METTL3_EV_vs_WT_F08.12334.12334.3 1.17E-06 25/76 K.QSAQLTALAAQQQAAGKEEK.S sp|Q96A49|SYAP1_HUMAN 1 2070.0705 1.33 116449 12334 3 2070.06933 691.0308 Synapse-associated protein 1 OS=Homo sapiens OX=9606 GN=SYAP1 PE=1 SV=1 6.14 2327.4 - 2.44E+08 - - - -0.5874 - 4.566 0.576 - 825.1 1 2 1 -0.0012 20 0 0 0 9.70E+09 7.29E+09 - - - 8.6457 0.9998 221125_WJC_METTL3_EV_vs_WT_F08.12335.12335.3 1.20E-05 16/68 K.QLDDK[136.11]DEEINQQSQLVEK[136.11].L sp|P33176|KINH_HUMAN 1 2174.0674 1.43 116450 12335 3 2174.063867 725.6964 Kinesin-1 heavy chain OS=Homo sapiens OX=9606 GN=KIF5B PE=1 SV=1 4.02 2327.5 - 2.71E+06 - - - -1.6117 - 2.628 0.502 - 354.5 1 2 1 -0.0035 18 0 0 0 4.59E+07 3.20E+07 - - - 6.5418 1 221125_WJC_METTL3_EV_vs_WT_F08.12338.12338.2 6.06E-11 20/34 R.GGGGGQDNGLEGLGNDSR.D sp|P08621|RU17_HUMAN 1 1658.7245 1.6 116453 12338 2 1658.7208 830.3695 U1 small nuclear ribonucleoprotein 70 kDa OS=Homo sapiens OX=9606 GN=SNRNP70 PE=1 SV=2 4.03 2327.8 - 1.35E+06 - - - -2.2029 - 3.449 0.705 - 1302.7 1 2 0 -0.0037 18 0 0 0 6.35E+07 3.97E+07 - - - 7.2909 1 221125_WJC_METTL3_EV_vs_WT_F08.12343.12343.2 7.25E-10 17/24 R.K[136.11]TEELEEESFPER[166.11].S "sp|Q9Y2W1|TR150_HUMAN,tr|A0A3B3ITZ9|A0A3B3ITZ9_HUMAN" 2 1639.7696 3.66 116456 12343 2 1639.770158 820.8921 Thyroid hormone receptor-associated protein 3 OS=Homo sapiens OX=9606 GN=THRAP3 PE=1 SV=2 4.21 2328.5 - 875537 - - - 0.3305 - 3.525 0.696 - 1176.5 1 2 0 0.0005 13 0 0 0 1.26E+08 3.44E+07 - - - 7.415 1 221125_WJC_METTL3_EV_vs_WT_F08.12347.12347.2 3.85E-11 23/38 K.QSAQLTALAAQQQAAGKEEK.S sp|Q96A49|SYAP1_HUMAN 1 2070.0705 1.38 116458 12347 2 2070.067785 1036.0425 Synapse-associated protein 1 OS=Homo sapiens OX=9606 GN=SYAP1 PE=1 SV=1 6.14 2328.9 - 5.48E+06 - - - -1.3338 - 4.472 0.683 - 1704.3 1 2 1 -0.0028 20 0 0 0 1.48E+08 1.07E+08 - - - 7.7673 0.9998 221125_WJC_METTL3_EV_vs_WT_F08.12348.12348.4 6.33E-05 19/102 K.AAVHTYGIASVPNQPLKK.Q "sp|Q9UHI6|DDX20_HUMAN,tr|A0A7P0T9T8|A0A7P0T9T8_HUMAN" 2 1893.0472 1.63 116459 12348 4 1893.046303 474.2691 Probable ATP-dependent RNA helicase DDX20 OS=Homo sapiens OX=9606 GN=DDX20 PE=1 SV=2 9.7 2329 - 2.74E+06 - - - -0.4907 - 3.053 0.379 - 265 1 2 0 -0.0009 18 0 0 0 6.98E+07 4.28E+07 - - - 2.9069 0.9999 221125_WJC_METTL3_EV_vs_WT_F08.12349.12349.3 2.04E-09 15/72 K.DAGTDKNPPETAPVEVVEK.K sp|Q96T58|MINT_HUMAN 1 1994.9797 29.49 116460 12349 3 1994.981888 666.0005 Msx2-interacting protein OS=Homo sapiens OX=9606 GN=SPEN PE=1 SV=1 4.18 2329.1 - 726598 - - - 1.1138 - 2.968 0.549 - 186.8 1 2 1 0.0022 19 0 0 0 2.70E+07 9.16E+05 - - - 7.3329 1 221125_WJC_METTL3_EV_vs_WT_F08.12353.12353.2 5.94E-10 18/34 R.GGGGGQDNGLEGLGNDSR[166.11].D sp|P08621|RU17_HUMAN 1 1668.7327 1.6 116462 12353 2 1668.728759 835.3736 U1 small nuclear ribonucleoprotein 70 kDa OS=Homo sapiens OX=9606 GN=SNRNP70 PE=1 SV=2 4.03 2329.7 - 2.58E+06 - - - -2.3761 - 3.005 0.636 - 949.6 1 2 0 -0.004 18 0 0 0 6.34E+07 3.97E+07 - - - 6.4423 0.9977 221125_WJC_METTL3_EV_vs_WT_F08.12358.12358.3 0.00548 15/60 K.LK[136.11]GEATVSFDDPPSAK[136.11].A "sp|P35637|FUS_HUMAN,tr|H3BPE7|H3BPE7_HUMAN" 2 1676.8592 0.95 116465 12358 3 1676.859412 559.9603 RNA-binding protein FUS OS=Homo sapiens OX=9606 GN=FUS PE=1 SV=1 4.56 2330.2 - 3.63E+06 - - - 0.1169 - 2.325 0.28 - 223.4 1 2 1 0.0002 16 0 0 0 1.02E+08 1.07E+08 - - - 3.8265 0.9993 221125_WJC_METTL3_EV_vs_WT_F08.12359.12359.4 0.00177 19/96 K.QHAVINYDASTDEHLVK.D "sp|Q5SW79|CE170_HUMAN,tr|E5RFU8|E5RFU8_HUMAN,tr|E5RIH6|E5RIH6_HUMAN,tr|E5RJT5|E5RJT5_HUMAN" 4 1938.9436 1.11 116466 12359 4 1938.939476 485.7432 Centrosomal protein of 170 kDa OS=Homo sapiens OX=9606 GN=CEP170 PE=1 SV=1 5.21 2330.3 - 1.04E+06 - - - -2.1037 - 2.979 0.326 - 234.3 1 2 0 -0.0041 17 0 0 0 1.74E+07 1.56E+07 - - - 2.4414 0.9998 221125_WJC_METTL3_EV_vs_WT_F08.12363.12363.3 1.13E-06 19/64 R.KASSPSPLTIGTPESQR.K sp|Q9NPI6|DCP1A_HUMAN 1 1754.9163 2.68 116468 12363 3 1754.921514 585.9794 mRNA-decapping enzyme 1A OS=Homo sapiens OX=9606 GN=DCP1A PE=1 SV=3 8.75 2330.8 - 1.82E+06 - - - 2.9842 - 3.336 0.375 - 537.2 1 2 0 0.0052 17 0 0 0 6.38E+07 2.38E+07 - - - 5.763 0.9962 221125_WJC_METTL3_EV_vs_WT_F08.12366.12366.3 3.28E-05 17/68 K.STGDIAGTVVPETNKEPR.Y "sp|Q9UDY2|ZO2_HUMAN,tr|A0A3B3IT83|A0A3B3IT83_HUMAN,tr|A0A2R8YDH4|A0A2R8YDH4_HUMAN,tr|A0A3B3IS03|A0A3B3IS03_HUMAN,tr|A0A3B3ISF1|A0A3B3ISF1_HUMAN,tr|A0A1B0GTW1|A0A1B0GTW1_HUMAN,tr|A0A3B3ISZ5|A0A3B3ISZ5_HUMAN,tr|A0A3B3IRV6|A0A3B3IRV6_HUMAN,tr|A0A3B3IU51|A0A3B3IU51_HUMAN,tr|A0A3B3IRI3|A0A3B3IRI3_HUMAN,tr|A0A3B3ITE1|A0A3B3ITE1_HUMAN" 11 1869.9432 1.01 116471 12366 3 1869.953735 624.3217 Tight junction protein ZO-2 OS=Homo sapiens OX=9606 GN=TJP2 PE=1 SV=2 4.68 2331.1 - 772193 - - - 5.6232 - 3.027 0.459 - 227.3 1 2 1 0.0105 18 0 0 0 2.37E+07 2.35E+07 - - - 6.4125 0.9764 221125_WJC_METTL3_EV_vs_WT_F08.12367.12367.3 0.0962 Aug-40 R.KKLEEELEGMR.R sp|P15924|DESP_HUMAN 1 1360.7021 999 116472 12367 3 1360.70142 454.5746 Desmoplakin OS=Homo sapiens OX=9606 GN=DSP PE=1 SV=3 4.95 2331.3 - 597367 - - - -0.4637 - 1.48 0.229 - 113.6 1 2 1 -0.0006 11 0 0 0 1.63E+07 0.00E+00 - - - 2.2067 1 221125_WJC_METTL3_EV_vs_WT_F08.12368.12368.4 1.21E-06 14/90 K.SHLLNC[160.03]C[160.03]PHDVLSGTR.M "sp|Q9Y383|LC7L2_HUMAN,tr|A0A0A6YYJ8|A0A0A6YYJ8_HUMAN" 2 1864.8672 5.7 116473 12368 4 1864.865646 467.2241 Putative RNA-binding protein Luc7-like 2 OS=Homo sapiens OX=9606 GN=LUC7L2 PE=1 SV=2 6.65 2331.4 - 1.37E+06 - - - -0.8526 - 2.201 0.525 - 118.5 1 2 0 -0.0016 16 0 0 0 2.93E+07 5.13E+06 - - - 4.0731 0.9998 221125_WJC_METTL3_EV_vs_WT_F08.12372.12372.4 9.89E-08 17/78 R.IVDDLKDEAEQYRK.M sp|O75533|SF3B1_HUMAN 1 1720.8632 0.4 116475 12372 4 1720.866563 431.2231 Splicing factor 3B subunit 1 OS=Homo sapiens OX=9606 GN=SF3B1 PE=1 SV=3 4.44 2331.9 - 1.69E+06 - - - 1.9665 - 3.475 0.513 - 259.2 1 2 1 0.0034 14 0 0 0 1.96E+07 4.88E+07 - - - 4.1435 0.9995 221125_WJC_METTL3_EV_vs_WT_F08.12373.12373.3 5.58E-07 14/52 R.IVDDLKDEAEQYRK.M sp|O75533|SF3B1_HUMAN 1 1720.8632 0.37 116476 12373 3 1720.868963 574.6283 Splicing factor 3B subunit 1 OS=Homo sapiens OX=9606 GN=SF3B1 PE=1 SV=3 4.44 2331.9 - 2.17E+06 - - - 3.3611 - 2.686 0.522 - 293.3 1 2 1 0.0058 14 0 0 0 3.23E+07 8.80E+07 - - - 6.984 0.9999 221125_WJC_METTL3_EV_vs_WT_F08.12379.12379.3 0.00174 13/52 K.SHLEVPLEENVNR[166.11]R[166.11].V "sp|Q96CT7|CC124_HUMAN,tr|M0R2F5|M0R2F5_HUMAN" 2 1710.8916 1.05 116480 12379 3 1710.889946 571.3045 Coiled-coil domain-containing protein 124 OS=Homo sapiens OX=9606 GN=CCDC124 PE=1 SV=1 5.47 2332.7 - 4.24E+06 - - - -0.979 - 2.217 0.383 - 216.5 1 2 0 -0.0017 14 0 0 0 1.44E+08 1.37E+08 - - - 4.9254 0.9998 221125_WJC_METTL3_EV_vs_WT_F08.12386.12386.4 1.43E-05 Dec-78 K.SHLEVPLEENVNRR.V "sp|Q96CT7|CC124_HUMAN,tr|M0R2F5|M0R2F5_HUMAN" 2 1690.8751 0.97 116485 12386 4 1690.872255 423.726 Coiled-coil domain-containing protein 124 OS=Homo sapiens OX=9606 GN=CCDC124 PE=1 SV=1 5.47 2333.5 - 3.22E+06 - - - -1.6713 - 2.34 0.398 - 196.8 1 2 0 -0.0028 14 0 0 0 1.13E+08 1.17E+08 - - - 2.9988 0.9996 221125_WJC_METTL3_EV_vs_WT_F08.12387.12387.3 5.15E-06 16/68 K.STGDIAGTVVPETNK[136.11]EPR[166.11].Y "sp|Q9UDY2|ZO2_HUMAN,tr|A0A3B3IT83|A0A3B3IT83_HUMAN,tr|A0A2R8YDH4|A0A2R8YDH4_HUMAN,tr|A0A3B3IS03|A0A3B3IS03_HUMAN,tr|A0A3B3ISF1|A0A3B3ISF1_HUMAN,tr|A0A1B0GTW1|A0A1B0GTW1_HUMAN,tr|A0A3B3ISZ5|A0A3B3ISZ5_HUMAN,tr|A0A3B3IRV6|A0A3B3IRV6_HUMAN,tr|A0A3B3IU51|A0A3B3IU51_HUMAN,tr|A0A3B3IRI3|A0A3B3IRI3_HUMAN,tr|A0A3B3ITE1|A0A3B3ITE1_HUMAN" 11 1887.9657 1.01 116486 12387 3 1887.968946 630.3292 Tight junction protein ZO-2 OS=Homo sapiens OX=9606 GN=TJP2 PE=1 SV=2 4.68 2333.7 - 722725 - - - 1.7246 - 2.822 0.421 - 238 1 2 1 0.0033 18 0 0 0 2.37E+07 2.35E+07 - - - 5.8162 0.9996 221125_WJC_METTL3_EV_vs_WT_F08.12394.12394.4 0.000625 17/108 K.DLHQPSLSPASPHSQGFER[166.11].G "sp|Q9BZF1|OSBL8_HUMAN,tr|F8VQX7|F8VQX7_HUMAN,tr|F8VVE7|F8VVE7_HUMAN,tr|F8VVD3|F8VVD3_HUMAN,tr|F8VZ43|F8VZ43_HUMAN" 5 2099.006 0.65 116491 12394 4 2098.999049 525.7588 Oxysterol-binding protein-related protein 8 OS=Homo sapiens OX=9606 GN=OSBPL8 PE=1 SV=3 5.99 2334.5 - 527406 - - - -3.3049 - 2.728 0.406 - 114 1 2 0 -0.0069 19 0 0 0 5.78E+06 8.95E+06 - - - 3.0974 0.9995 221125_WJC_METTL3_EV_vs_WT_F08.12397.12397.4 1.09E-06 15/90 K.VSRPLELC[160.03]YAPTKDPK.- sp|Q06587|RING1_HUMAN 1 1872.9768 1.27 116492 12397 4 1872.975936 469.2515 E3 ubiquitin-protein ligase RING1 OS=Homo sapiens OX=9606 GN=RING1 PE=1 SV=2 8.15 2334.9 - 995197 - - - -0.4447 - 2.73 0.405 - 145.1 1 2 1 -0.0008 16 0 0 0 1.77E+07 1.40E+07 - - - 3.1047 1 221125_WJC_METTL3_EV_vs_WT_F08.12401.12401.3 0.0473 Dec-64 R.K[136.11]ASSPSPLTIGTPESQR[166.11].K sp|Q9NPI6|DCP1A_HUMAN 1 1772.9387 2.68 116496 12401 3 1772.937987 591.9869 mRNA-decapping enzyme 1A OS=Homo sapiens OX=9606 GN=DCP1A PE=1 SV=3 8.75 2335.4 - 791520 - - - -0.4287 - 2.65 0.441 - 131.4 1 2 0 -0.0008 17 0 0 0 6.38E+07 2.38E+07 - - - 5.9185 0.9995 221125_WJC_METTL3_EV_vs_WT_F08.12403.12403.3 0.000101 Dec-68 K.ENVPPGPEVC[160.03]ITHQEGEK.L "sp|Q9UHB6|LIMA1_HUMAN,tr|F8VRN8|F8VRN8_HUMAN,tr|F8VQE1|F8VQE1_HUMAN,tr|F8VS07|F8VS07_HUMAN" 4 2018.9368 0.85 116498 12403 3 2018.931796 673.9862 LIM domain and actin-binding protein 1 OS=Homo sapiens OX=9606 GN=LIMA1 PE=1 SV=1 4.48 2335.7 - 441085 - - - -2.4562 - 1.913 0.398 - 135.5 1 2 0 -0.005 18 0 0 0 1.63E+07 1.93E+07 - - - 4.5912 0.9999 221125_WJC_METTL3_EV_vs_WT_F08.12415.12415.3 0.000277 13/44 R.K[136.11]IHIDLPNEQAR[166.11].L "sp|P62333|PRS10_HUMAN,tr|A0A087X2I1|A0A087X2I1_HUMAN" 2 1450.8011 6.65 116506 12415 3 1450.803282 484.6077 26S proteasome regulatory subunit 10B OS=Homo sapiens OX=9606 GN=PSMC6 PE=1 SV=1 6.75 2337.2 - 768993 - - - 1.4819 - 2.757 0.414 - 317 1 2 0 0.0022 12 0 0 0 1.45E+08 2.18E+07 - - - 5.9661 0.9999 221125_WJC_METTL3_EV_vs_WT_F08.12418.12418.4 3.20E-05 13/84 K.KVNPDLQVEVKPSIR.A sp|Q96KR1|ZFR_HUMAN 1 1720.9836 1.28 116509 12418 4 1720.980155 431.2532 Zinc finger RNA-binding protein OS=Homo sapiens OX=9606 GN=ZFR PE=1 SV=2 8.59 2337.6 - 438338 - - - -1.9837 - 2.649 0.458 - 155.2 1 2 0 -0.0034 15 0 0 0 6.27E+06 4.89E+06 - - - 3.5601 1 221125_WJC_METTL3_EV_vs_WT_F08.12425.12425.3 2.18E-09 20/64 R.C[160.03]SAGLGALAQR[166.11]PGSVSK[136.11].W "sp|Q9NXV2|KCTD5_HUMAN,tr|H3BSS5|H3BSS5_HUMAN" 2 1675.8795 3.99 116513 12425 3 1675.880592 559.6338 BTB\POZ domain-containing protein KCTD5 OS=Homo sapiens OX=9606 GN=KCTD5 PE=1 SV=1 9.51 2338.4 - 1.42E+06 - - - 0.6761 - 3.729 0.626 - 652.4 1 2 0 0.0011 17 0 0 0 9.40E+07 2.35E+07 - - - 8.8439 0.9895 221125_WJC_METTL3_EV_vs_WT_F08.12427.12427.3 3.10E-05 Dec-84 F.ASAAGGGGSEAAGAEQALVR[166.11]PR[166.11].G "sp|O75896|TUSC2_HUMAN,tr|G3V0I0|G3V0I0_HUMAN,tr|F2Z2A9|F2Z2A9_HUMAN" 3 2002.0095 0.43 116515 12427 3 2002.012154 668.3438 Tumor suppressor candidate 2 OS=Homo sapiens OX=9606 GN=TUSC2 PE=1 SV=3 6.19 2338.6 - 377858 - - - 1.3232 - 2.196 0.452 - 106.8 1 1 0 0.0027 22 0 0 0 2.76E+06 6.36E+06 - - - 5.4436 1 221125_WJC_METTL3_EV_vs_WT_F08.12429.12429.3 4.44E-05 Nov-68 K.ENVPPGPEVC[160.03]ITHQEGEK[136.11].L "sp|Q9UHB6|LIMA1_HUMAN,tr|F8VRN8|F8VRN8_HUMAN,tr|F8VQE1|F8VQE1_HUMAN,tr|F8VS07|F8VS07_HUMAN" 4 2026.951 1.01 116517 12429 3 2026.948598 676.6576 LIM domain and actin-binding protein 1 OS=Homo sapiens OX=9606 GN=LIMA1 PE=1 SV=1 4.48 2338.9 - 332586 - - - -1.1628 - 2.09 0.509 - 129.3 1 2 0 -0.0024 18 0 0 0 2.08E+07 2.07E+07 - - - 6.0498 0.9992 221125_WJC_METTL3_EV_vs_WT_F08.12432.12432.3 4.23E-05 Sep-64 R.SSC[160.03]PLANSQYATIK[136.11]EEK[136.11].G "sp|Q9BXY0|MAK16_HUMAN,tr|H0YBV6|H0YBV6_HUMAN" 2 1940.9484 3.83 116520 12432 3 1940.95162 647.9901 Protein MAK16 homolog OS=Homo sapiens OX=9606 GN=MAK16 PE=1 SV=2 5.86 2339.3 - 115126 - - - 1.6373 - 1.671 0.466 - 79.1 1 2 1 0.0032 17 0 0 0 2.92E+07 7.63E+06 - - - 5.0316 0.9997 221125_WJC_METTL3_EV_vs_WT_F08.12436.12436.3 2.34E-05 13/52 R.QIILEK[136.11]EETEELK[136.11]R[166.11].F "sp|P12956|XRCC6_HUMAN,tr|B1AHC9|B1AHC9_HUMAN" 2 1782.9938 0.001 116522 12436 3 1782.997828 595.3385 X-ray repair cross-complementing protein 6 OS=Homo sapiens OX=9606 GN=XRCC6 PE=1 SV=2 4.65 2339.8 - 336259 - - - 2.2872 - 2.962 0.467 - 226.1 1 2 1 0.0041 14 0 0 0 0.00E+00 2.73E+06 - - - 6.6312 1 221125_WJC_METTL3_EV_vs_WT_F08.12437.12437.3 6.47E-08 16/64 R.C[160.03]SAGLGALAQRPGSVSK.W "sp|Q9NXV2|KCTD5_HUMAN,tr|H3BSS5|H3BSS5_HUMAN" 2 1657.857 4.01 116523 12437 3 1657.860494 553.6263 BTB\POZ domain-containing protein KCTD5 OS=Homo sapiens OX=9606 GN=KCTD5 PE=1 SV=1 9.51 2339.9 - 6.96E+06 - - - 2.1142 - 3.545 0.568 - 410.4 1 2 0 0.0035 17 0 0 0 9.43E+07 2.35E+07 - - - 8.0688 1 221125_WJC_METTL3_EV_vs_WT_F08.12438.12438.3 0.00145 16/36 K.RLHVSNIPFR.F "sp|O43251|RFOX2_HUMAN,sp|Q9NWB1|RFOX1_HUMAN,sp|A6NFN3|RFOX3_HUMAN,tr|A0A6Q8PGE0|A0A6Q8PGE0_HUMAN,tr|A0A6Q8PH77|A0A6Q8PH77_HUMAN,tr|A0A286YEU2|A0A286YEU2_HUMAN,tr|A0A087X2B1|A0A087X2B1_HUMAN,tr|F8VR27|F8VR27_HUMAN,tr|B7Z1U7|B7Z1U7_HUMAN,tr|B0QYY6|B0QYY6_HUMAN,tr|B0QYV1|B0QYV1_HUMAN,tr|A0A6Q8PHA3|A0A6Q8PHA3_HUMAN,tr|A0A3B3ITL7|A0A3B3ITL7_HUMAN,tr|F8VZY7|F8VZY7_HUMAN,tr|B0QYY4|B0QYY4_HUMAN,tr|J3KNW3|J3KNW3_HUMAN,tr|F8VZG9|F8VZG9_HUMAN,tr|J3QRF4|J3QRF4_HUMAN,tr|F8VRS4|F8VRS4_HUMAN,tr|A0A6Q8PFM4|A0A6Q8PFM4_HUMAN,tr|S4R469|S4R469_HUMAN,tr|A0A804HKG7|A0A804HKG7_HUMAN,tr|A0A0G2JRA5|A0A0G2JRA5_HUMAN,tr|A0A804HJM2|A0A804HJM2_HUMAN,tr|J3QQZ2|J3QQZ2_HUMAN,tr|I3L1D4|I3L1D4_HUMAN,tr|B0QYY7|B0QYY7_HUMAN,tr|A0A0G2JSB3|A0A0G2JSB3_HUMAN" 28 1237.7044 1.16 116524 12438 3 1237.706217 413.5754 RNA binding protein fox-1 homolog 2 OS=Homo sapiens OX=9606 GN=RBFOX2 PE=1 SV=3 12 2340 - 531029 - - - 1.489 - 2.993 0.444 - 499.1 1 2 0 0.0018 10 0 0 0 4.51E+07 3.90E+07 - - - 6.6913 0.9721 221125_WJC_METTL3_EV_vs_WT_F08.12439.12439.3 0.0118 Sep-64 K.QAGPASVPLR[166.11]TEEEFK[136.11]K[136.11].F sp|P30101|PDIA3_HUMAN 1 1912.0264 0.69 116525 12439 3 1912.030653 638.3494 Protein disulfide-isomerase A3 OS=Homo sapiens OX=9606 GN=PDIA3 PE=1 SV=4 6.23 2340.1 - 499152 - - - 2.1998 - 1.995 0.208 - 76.3 1 2 1 0.0042 17 0 0 0 5.67E+06 8.22E+06 - - - 2.6026 0.9388 221125_WJC_METTL3_EV_vs_WT_F08.12442.12442.4 0.156 Aug-96 R.AKNPYEEADHNSLAEIR.T sp|Q09328|MGT5A_HUMAN 1 1955.9337 2.75 116528 12442 4 1955.935172 489.9907 "Alpha-1,6-mannosylglycoprotein 6-beta-N-acetylglucosaminyltransferase A OS=Homo sapiens OX=9606 GN=MGAT5 PE=1 SV=1" 4.83 2340.5 - 184995 - - - 0.7434 - 1.696 0.183 - 33.4 1 2 1 0.0015 17 0 0 0 2.59E+06 9.43E+05 - - - 1.0018 1 221125_WJC_METTL3_EV_vs_WT_F08.12444.12444.2 2.01E-06 Oct-32 R.C[160.03]SAGLGALAQRPGSVSK.W "sp|Q9NXV2|KCTD5_HUMAN,tr|H3BSS5|H3BSS5_HUMAN" 2 1657.857 999 116529 12444 2 1657.858944 829.9358 BTB\POZ domain-containing protein KCTD5 OS=Homo sapiens OX=9606 GN=KCTD5 PE=1 SV=1 9.51 2340.7 - 230131 - - - 1.1792 - 2.39 0.623 - 200 1 2 0 0.002 17 0 0 0 2.87E+06 0.00E+00 - - - 5.784 0.9676 221125_WJC_METTL3_EV_vs_WT_F08.12448.12448.3 0.00147 13/64 K.QAGPASVPLRTEEEFKK.F sp|P30101|PDIA3_HUMAN 1 1885.9898 0.68 116532 12448 3 1885.996954 629.6705 Protein disulfide-isomerase A3 OS=Homo sapiens OX=9606 GN=PDIA3 PE=1 SV=4 6.23 2341.1 - 548372 - - - 3.8054 - 2.126 0.254 - 178.4 1 2 1 0.0072 17 0 0 0 4.91E+06 7.25E+06 - - - 3.2753 0.9975 221125_WJC_METTL3_EV_vs_WT_F08.12450.12450.3 0.00201 Nov-64 R.LQEDPNYSPQRFPNAQR.A "sp|P46379|BAG6_HUMAN,tr|A0A7I2V508|A0A7I2V508_HUMAN,tr|H0Y710|H0Y710_HUMAN,tr|H0Y4L1|H0Y4L1_HUMAN,tr|A0A7P0MQS5|A0A7P0MQS5_HUMAN,tr|A0A0G2JL47|A0A0G2JL47_HUMAN,tr|A0A024RCR6|A0A024RCR6_HUMAN,tr|A0A0G2JK23|A0A0G2JK23_HUMAN" 8 2058.9872 1.35 116534 12450 3 2058.991632 687.3363 Large proline-rich protein BAG6 OS=Homo sapiens OX=9606 GN=BAG6 PE=1 SV=2 6.07 2341.4 - 502550 - - - 2.1763 - 2.063 0.36 - 102.1 1 2 1 0.0045 17 0 0 0 1.25E+07 9.26E+06 - - - 4.3819 0.9999 221125_WJC_METTL3_EV_vs_WT_F08.12454.12454.3 1.88E-07 13/88 R.QPPPAPPEQADGNAPGPQPPPVR.L sp|Q12948|FOXC1_HUMAN 1 2313.1502 999 116538 12454 3 2313.155801 772.0573 Forkhead box protein C1 OS=Homo sapiens OX=9606 GN=FOXC1 PE=1 SV=3 4.37 2341.9 - 250317 - - - 2.424 - 2.349 0.507 - 119.2 1 2 0 0.0056 23 0 0 0 4.29E+06 0.00E+00 - - - 6.1944 0.9999 221125_WJC_METTL3_EV_vs_WT_F08.12461.12461.3 1.25E-05 16/36 K.R[166.11]LHVSNIPFR[166.11].F "sp|O43251|RFOX2_HUMAN,sp|Q9NWB1|RFOX1_HUMAN,sp|A6NFN3|RFOX3_HUMAN,tr|A0A6Q8PGE0|A0A6Q8PGE0_HUMAN,tr|A0A6Q8PH77|A0A6Q8PH77_HUMAN,tr|A0A286YEU2|A0A286YEU2_HUMAN,tr|A0A087X2B1|A0A087X2B1_HUMAN,tr|F8VR27|F8VR27_HUMAN,tr|B7Z1U7|B7Z1U7_HUMAN,tr|B0QYY6|B0QYY6_HUMAN,tr|B0QYV1|B0QYV1_HUMAN,tr|A0A6Q8PHA3|A0A6Q8PHA3_HUMAN,tr|A0A3B3ITL7|A0A3B3ITL7_HUMAN,tr|F8VZY7|F8VZY7_HUMAN,tr|B0QYY4|B0QYY4_HUMAN,tr|J3KNW3|J3KNW3_HUMAN,tr|F8VZG9|F8VZG9_HUMAN,tr|J3QRF4|J3QRF4_HUMAN,tr|F8VRS4|F8VRS4_HUMAN,tr|A0A6Q8PFM4|A0A6Q8PFM4_HUMAN,tr|S4R469|S4R469_HUMAN,tr|A0A804HKG7|A0A804HKG7_HUMAN,tr|A0A0G2JRA5|A0A0G2JRA5_HUMAN,tr|A0A804HJM2|A0A804HJM2_HUMAN,tr|J3QQZ2|J3QQZ2_HUMAN,tr|I3L1D4|I3L1D4_HUMAN,tr|B0QYY7|B0QYY7_HUMAN,tr|A0A0G2JSB3|A0A0G2JSB3_HUMAN" 28 1257.7209 1.16 116543 12461 3 1257.722377 420.2476 RNA binding protein fox-1 homolog 2 OS=Homo sapiens OX=9606 GN=RBFOX2 PE=1 SV=3 12 2342.8 - 2.62E+06 - - - 1.1632 - 3.316 0.34 - 619.3 1 2 0 0.0015 10 0 0 0 4.51E+07 3.90E+07 - - - 5.8312 0.9955 221125_WJC_METTL3_EV_vs_WT_F08.12462.12462.3 6.04E-09 15/52 G.RIEDVTPIPSDSTR.R "sp|P62263|RS14_HUMAN,tr|A0A2R8Y811|A0A2R8Y811_HUMAN" 2 1584.8108 1.09 116544 12462 3 1584.815187 529.2775 40S ribosomal protein S14 OS=Homo sapiens OX=9606 GN=RPS14 PE=1 SV=3 4.56 2342.9 - 801888 - - - 2.7997 - 2.844 0.581 - 366.6 1 1 0 0.0044 14 0 0 0 1.36E+07 1.25E+07 - - - 7.794 0.9995 221125_WJC_METTL3_EV_vs_WT_F08.12464.12464.4 8.40E-06 19/78 K.VIEPLKDFHKDEVR.L sp|P49915|GUAA_HUMAN 1 1723.9257 0.97 116546 12464 4 1723.928526 431.9887 GMP synthase [glutamine-hydrolyzing] OS=Homo sapiens OX=9606 GN=GMPS PE=1 SV=1 5.48 2343.1 - 444354 - - - 1.6277 - 3.33 0.406 - 349.3 1 2 2 0.0028 14 0 0 0 2.30E+07 2.36E+07 - - - 3.1969 0.9992 221125_WJC_METTL3_EV_vs_WT_F08.12466.12466.3 1.50E-05 Nov-52 K.YDGK[136.11]WEVEEMK[136.11]ESK[136.11].L "sp|P27824|CALX_HUMAN,tr|A0A7P0T937|A0A7P0T937_HUMAN,tr|A0A7P0T840|A0A7P0T840_HUMAN,tr|A0A7P0Z4H2|A0A7P0Z4H2_HUMAN,tr|A0A7P0TB65|A0A7P0TB65_HUMAN,tr|A0A7P0TAN9|A0A7P0TAN9_HUMAN,tr|A0A7P0TAE9|A0A7P0TAE9_HUMAN,tr|A0A7P0T8N1|A0A7P0T8N1_HUMAN,tr|A0A7P0T8G1|A0A7P0T8G1_HUMAN,tr|A0A7P0Z4D6|A0A7P0Z4D6_HUMAN,tr|A0A7P0Z484|A0A7P0Z484_HUMAN,tr|A0A7P0TAR9|A0A7P0TAR9_HUMAN,tr|A0A7P0T9L0|A0A7P0T9L0_HUMAN,tr|D6RAU8|D6RAU8_HUMAN" 14 1780.8404 1.14 116548 12466 3 1780.844378 594.6207 Calnexin OS=Homo sapiens OX=9606 GN=CANX PE=1 SV=2 4.59 2343.4 - 408986 - - - 2.2327 - 2.457 0.409 - 88.2 1 2 2 0.004 14 0 0 0 3.26E+07 2.85E+07 - - - 5.4878 1 221125_WJC_METTL3_EV_vs_WT_F08.12468.12468.2 1.07E-12 15/32 K.TTPTPSTNSVLSTSTNR[166.11].S "sp|Q7KZI7|MARK2_HUMAN,tr|A0A0A0MRU9|A0A0A0MRU9_HUMAN,tr|E7ETY4|E7ETY4_HUMAN,tr|A0A7I2YQR3|A0A7I2YQR3_HUMAN,tr|E9PC69|E9PC69_HUMAN,tr|A0A7I2V3R3|A0A7I2V3R3_HUMAN" 6 1772.878 0.94 116550 12468 2 1772.882468 887.4463 Serine\threonine-protein kinase MARK2 OS=Homo sapiens OX=9606 GN=MARK2 PE=1 SV=2 9.41 2343.6 - 290038 - - - 2.5253 - 3.03 0.664 - 517.3 1 2 0 0.0045 17 0 0 0 1.50E+07 1.59E+07 - - - 6.6694 1 221125_WJC_METTL3_EV_vs_WT_F08.12469.12469.2 4.38E-08 Nov-32 K.TTPTPSTNSVLSTSTNR.S "sp|Q7KZI7|MARK2_HUMAN,tr|A0A0A0MRU9|A0A0A0MRU9_HUMAN,tr|E7ETY4|E7ETY4_HUMAN,tr|A0A7I2YQR3|A0A7I2YQR3_HUMAN,tr|E9PC69|E9PC69_HUMAN,tr|A0A7I2V3R3|A0A7I2V3R3_HUMAN" 6 1762.8697 0.94 116551 12469 2 1762.873983 882.4421 Serine\threonine-protein kinase MARK2 OS=Homo sapiens OX=9606 GN=MARK2 PE=1 SV=2 9.41 2343.8 - 261034 - - - 2.4176 - 2.381 0.619 - 207.3 1 2 0 0.0043 17 0 0 0 1.50E+07 1.59E+07 - - - 5.7444 0.9999 221125_WJC_METTL3_EV_vs_WT_F08.12476.12476.3 0.0024 14/48 R.KTEELEEESFPER.S "sp|Q9Y2W1|TR150_HUMAN,tr|A0A3B3ITZ9|A0A3B3ITZ9_HUMAN" 2 1621.7471 3.08 116557 12476 3 1621.75119 541.5897 Thyroid hormone receptor-associated protein 3 OS=Homo sapiens OX=9606 GN=THRAP3 PE=1 SV=2 4.21 2344.6 - 3.38E+06 - - - 2.4936 - 2.696 0.476 - 316.6 1 2 0 0.004 13 0 0 0 1.16E+09 3.77E+08 - - - 6.5348 0.9997 221125_WJC_METTL3_EV_vs_WT_F08.12478.12478.4 2.80E-05 14/78 K.VIEPLK[136.11]DFHK[136.11]DEVR[166.11].L sp|P49915|GUAA_HUMAN 1 1749.9624 0.98 116559 12478 4 1749.965327 438.4979 GMP synthase [glutamine-hydrolyzing] OS=Homo sapiens OX=9606 GN=GMPS PE=1 SV=1 5.48 2344.8 - 1.04E+06 - - - 1.6783 - 3.267 0.458 - 169.5 1 2 2 0.0029 14 0 0 0 2.31E+07 2.36E+07 - - - 3.6425 0.9997 221125_WJC_METTL3_EV_vs_WT_F08.12485.12485.3 0.000516 Dec-52 K.YDGKWEVEEMKESK.L "sp|P27824|CALX_HUMAN,tr|A0A7P0T937|A0A7P0T937_HUMAN,tr|A0A7P0T840|A0A7P0T840_HUMAN,tr|A0A7P0Z4H2|A0A7P0Z4H2_HUMAN,tr|A0A7P0TB65|A0A7P0TB65_HUMAN,tr|A0A7P0TAN9|A0A7P0TAN9_HUMAN,tr|A0A7P0TAE9|A0A7P0TAE9_HUMAN,tr|A0A7P0T8N1|A0A7P0T8N1_HUMAN,tr|A0A7P0T8G1|A0A7P0T8G1_HUMAN,tr|A0A7P0Z4D6|A0A7P0Z4D6_HUMAN,tr|A0A7P0Z484|A0A7P0Z484_HUMAN,tr|A0A7P0TAR9|A0A7P0TAR9_HUMAN,tr|A0A7P0T9L0|A0A7P0T9L0_HUMAN,tr|D6RAU8|D6RAU8_HUMAN" 14 1756.7978 1.14 116564 12485 3 1756.801013 586.6065 Calnexin OS=Homo sapiens OX=9606 GN=CANX PE=1 SV=2 4.59 2345.7 - 1.18E+06 - - - 1.8278 - 2.23 0.516 - 102.9 1 2 2 0.0032 14 0 0 0 3.25E+07 2.85E+07 - - - 6.4233 1 221125_WJC_METTL3_EV_vs_WT_F08.12486.12486.3 1.91E-07 20/56 R.KHPAPPPSNYEILVK.A "sp|Q9Y2L1|RRP44_HUMAN,tr|G3V1J5|G3V1J5_HUMAN" 2 1688.925 1.54 116565 12486 3 1688.928591 563.9823 Exosome complex exonuclease RRP44 OS=Homo sapiens OX=9606 GN=DIS3 PE=1 SV=2 8.51 2345.8 - 1.16E+06 - - - 2.1309 - 3.544 0.528 - 649.6 1 2 0 0.0036 15 0 0 0 1.26E+07 8.19E+06 - - - 7.7272 0.999 221125_WJC_METTL3_EV_vs_WT_F08.12487.12487.4 5.84E-05 Oct-78 K.YDGK[136.11]WEVEEMK[136.11]ESK[136.11].L "sp|P27824|CALX_HUMAN,tr|A0A7P0T937|A0A7P0T937_HUMAN,tr|A0A7P0T840|A0A7P0T840_HUMAN,tr|A0A7P0Z4H2|A0A7P0Z4H2_HUMAN,tr|A0A7P0TB65|A0A7P0TB65_HUMAN,tr|A0A7P0TAN9|A0A7P0TAN9_HUMAN,tr|A0A7P0TAE9|A0A7P0TAE9_HUMAN,tr|A0A7P0T8N1|A0A7P0T8N1_HUMAN,tr|A0A7P0T8G1|A0A7P0T8G1_HUMAN,tr|A0A7P0Z4D6|A0A7P0Z4D6_HUMAN,tr|A0A7P0Z484|A0A7P0Z484_HUMAN,tr|A0A7P0TAR9|A0A7P0TAR9_HUMAN,tr|A0A7P0T9L0|A0A7P0T9L0_HUMAN,tr|D6RAU8|D6RAU8_HUMAN" 14 1780.8404 0.99 116566 12487 4 1780.844625 446.2174 Calnexin OS=Homo sapiens OX=9606 GN=CANX PE=1 SV=2 4.59 2345.8 - 1.66E+06 - - - 2.3714 - 1.923 0.414 - 38.1 1 2 2 0.0042 14 0 0 0 2.99E+07 3.03E+07 - - - 3.0663 0.9996 221125_WJC_METTL3_EV_vs_WT_F08.12488.12488.4 4.02E-06 16/78 K.YDGKWEVEEMKESK.L "sp|P27824|CALX_HUMAN,tr|A0A7P0T937|A0A7P0T937_HUMAN,tr|A0A7P0T840|A0A7P0T840_HUMAN,tr|A0A7P0Z4H2|A0A7P0Z4H2_HUMAN,tr|A0A7P0TB65|A0A7P0TB65_HUMAN,tr|A0A7P0TAN9|A0A7P0TAN9_HUMAN,tr|A0A7P0TAE9|A0A7P0TAE9_HUMAN,tr|A0A7P0T8N1|A0A7P0T8N1_HUMAN,tr|A0A7P0T8G1|A0A7P0T8G1_HUMAN,tr|A0A7P0Z4D6|A0A7P0Z4D6_HUMAN,tr|A0A7P0Z484|A0A7P0Z484_HUMAN,tr|A0A7P0TAR9|A0A7P0TAR9_HUMAN,tr|A0A7P0T9L0|A0A7P0T9L0_HUMAN,tr|D6RAU8|D6RAU8_HUMAN" 14 1756.7978 0.99 116567 12488 4 1756.804672 440.2067 Calnexin OS=Homo sapiens OX=9606 GN=CANX PE=1 SV=2 4.59 2345.9 - 1.12E+06 - - - 3.9105 - 2.551 0.57 - 106.2 1 2 2 0.0069 14 0 0 0 2.93E+07 2.96E+07 - - - 4.5262 0.9999 221125_WJC_METTL3_EV_vs_WT_F08.12495.12495.3 6.89E-05 15/48 R.K[136.11]TEELEEESFPER[166.11].S "sp|Q9Y2W1|TR150_HUMAN,tr|A0A3B3ITZ9|A0A3B3ITZ9_HUMAN" 2 1639.7696 3.1 116573 12495 3 1639.767945 547.5971 Thyroid hormone receptor-associated protein 3 OS=Homo sapiens OX=9606 GN=THRAP3 PE=1 SV=2 4.21 2346.7 - 848558 - - - -1.019 - 2.387 0.413 - 368.2 1 2 0 -0.0017 13 0 0 0 1.17E+09 3.78E+08 - - - 5.503 0.9999 221125_WJC_METTL3_EV_vs_WT_F08.12497.12497.3 0.000262 19/56 R.K[136.11]HPAPPPSNYEILVK[136.11].A "sp|Q9Y2L1|RRP44_HUMAN,tr|G3V1J5|G3V1J5_HUMAN" 2 1704.9534 1.57 116575 12497 3 1704.955192 569.3251 Exosome complex exonuclease RRP44 OS=Homo sapiens OX=9606 GN=DIS3 PE=1 SV=2 8.51 2346.9 - 898285 - - - 1.0557 - 3.492 0.338 - 617 1 2 0 0.0018 15 0 0 0 1.20E+07 7.66E+06 - - - 5.5708 0.9999 221125_WJC_METTL3_EV_vs_WT_F08.12498.12498.4 2.35E-07 Dec-96 R.TDEEGK[136.11]DVPDHAVLEMK[136.11].A "sp|Q9BUJ2|HNRL1_HUMAN,tr|A0A0A0MRA5|A0A0A0MRA5_HUMAN,tr|M0R3F1|M0R3F1_HUMAN,tr|B7Z4B8|B7Z4B8_HUMAN" 4 1927.9168 1.86 116576 12498 4 1927.915474 482.9865 Heterogeneous nuclear ribonucleoprotein U-like protein 1 OS=Homo sapiens OX=9606 GN=HNRNPUL1 PE=1 SV=2 4.29 2347 - 529768 - - - -0.6919 - 2.778 0.544 - 81.2 1 2 1 -0.0013 17 0 0 0 8.53E+07 4.59E+07 - - - 4.3153 0.9997 221125_WJC_METTL3_EV_vs_WT_F08.12499.12499.4 9.67E-06 14/84 R.KHPAPPPSNYEILVK.A "sp|Q9Y2L1|RRP44_HUMAN,tr|G3V1J5|G3V1J5_HUMAN" 2 1688.925 1.86 116577 12499 4 1688.930498 423.2385 Exosome complex exonuclease RRP44 OS=Homo sapiens OX=9606 GN=DIS3 PE=1 SV=2 8.51 2347.2 - 294197 - - - 3.2601 - 2.821 0.425 - 187.9 1 2 0 0.0055 15 0 0 0 2.76E+06 1.48E+06 - - - 3.2948 0.977 221125_WJC_METTL3_EV_vs_WT_F08.12502.12502.4 0.000402 13/78 R.K[136.11]IELFGR[166.11]PHNVQPN.W sp|Q86U44|MTA70_HUMAN 1 1665.907 0.01 116579 12502 4 1665.908463 417.484 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 8.75 2347.5 - 4.53E+06 - - - 0.8818 - 2.228 0.379 - 183 1 1 0 0.0015 14 0 0 0 1.54E+06 1.98E+08 - - - 2.816 0.9973 221125_WJC_METTL3_EV_vs_WT_F08.12504.12504.3 0.0485 13/44 K.QK[136.11]QNR[166.11]PIPQWIR[166.11].M "sp|P62891|RL39_HUMAN,sp|Q59GN2|R39L5_HUMAN" 2 1590.9101 0.71 116580 12504 3 1590.914317 531.3106 60S ribosomal protein L39 OS=Homo sapiens OX=9606 GN=RPL39 PE=1 SV=2 12.01 2347.7 - 2.25E+06 - - - 2.6387 - 2.188 0.347 - 286.5 1 2 1 0.0042 12 0 0 0 2.37E+07 3.33E+07 - - - 4.5779 0.9843 221125_WJC_METTL3_EV_vs_WT_F08.12505.12505.3 0.0014 Dec-52 K.VIEPLKDFHKDEVR.L sp|P49915|GUAA_HUMAN 1 1723.9257 1.64 116581 12505 3 1723.936689 575.6492 GMP synthase [glutamine-hydrolyzing] OS=Homo sapiens OX=9606 GN=GMPS PE=1 SV=1 5.48 2347.8 - 655102 - - - 6.3628 - 2.534 0.39 - 204.9 1 2 2 0.011 14 0 0 0 8.51E+06 5.20E+06 - - - 5.356 1 221125_WJC_METTL3_EV_vs_WT_F08.12516.12516.4 5.37E-08 18/96 R.TDEEGKDVPDHAVLEMK.A "sp|Q9BUJ2|HNRL1_HUMAN,tr|A0A0A0MRA5|A0A0A0MRA5_HUMAN,tr|M0R3F1|M0R3F1_HUMAN,tr|B7Z4B8|B7Z4B8_HUMAN" 4 1911.8884 1.86 116590 12516 4 1911.891912 478.9794 Heterogeneous nuclear ribonucleoprotein U-like protein 1 OS=Homo sapiens OX=9606 GN=HNRNPUL1 PE=1 SV=2 4.29 2349.1 - 3.13E+06 - - - 1.8327 - 3.279 0.644 - 334.4 1 2 1 0.0035 17 0 0 0 8.53E+07 4.59E+07 - - - 5.2427 1 221125_WJC_METTL3_EV_vs_WT_F08.12517.12517.3 5.50E-09 21/64 R.TDEEGK[136.11]DVPDHAVLEMK[136.11].A "sp|Q9BUJ2|HNRL1_HUMAN,tr|A0A0A0MRA5|A0A0A0MRA5_HUMAN,tr|M0R3F1|M0R3F1_HUMAN,tr|B7Z4B8|B7Z4B8_HUMAN" 4 1927.9168 1.71 116591 12517 3 1927.916487 643.6462 Heterogeneous nuclear ribonucleoprotein U-like protein 1 OS=Homo sapiens OX=9606 GN=HNRNPUL1 PE=1 SV=2 4.29 2349.2 - 1.15E+06 - - - -0.1665 - 4.349 0.652 - 583.5 1 2 1 -0.0003 17 0 0 0 5.22E+07 3.05E+07 - - - 9.5226 1 221125_WJC_METTL3_EV_vs_WT_F08.12518.12518.3 2.31E-06 15/64 K.TQLQENETHSQLTNLER.K sp|Q96LB3|IFT74_HUMAN 1 2039.9872 5.94 116592 12518 3 2039.99254 681.003 Intraflagellar transport protein 74 homolog OS=Homo sapiens OX=9606 GN=IFT74 PE=1 SV=1 4.75 2349.2 - 1.07E+06 - - - 2.6123 - 3.56 0.528 - 238.3 1 2 0 0.0053 17 0 0 0 1.15E+07 1.94E+06 - - - 7.633 0.9985 221125_WJC_METTL3_EV_vs_WT_F08.12520.12520.3 2.47E-08 15/52 K.VIEPLK[136.11]DFHK[136.11]DEVR[166.11].L sp|P49915|GUAA_HUMAN 1 1749.9624 1.54 116594 12520 3 1749.971668 584.3281 GMP synthase [glutamine-hydrolyzing] OS=Homo sapiens OX=9606 GN=GMPS PE=1 SV=1 5.48 2349.4 - 556589 - - - 5.3018 - 3.015 0.529 - 356.8 1 2 2 0.0093 14 0 0 0 8.01E+06 5.20E+06 - - - 7.3681 0.9998 221125_WJC_METTL3_EV_vs_WT_F08.12528.12528.3 1.94E-05 Dec-56 K.NLSDSEKELYIQHAK.E sp|Q00059|TFAM_HUMAN 1 1773.8897 1.29 116600 12528 3 1773.886331 592.3039 "Transcription factor A, mitochondrial OS=Homo sapiens OX=9606 GN=TFAM PE=1 SV=1" 5.45 2350.4 - 1.40E+06 - - - -1.915 - 2.512 0.499 - 152.5 1 2 1 -0.0034 15 0 0 0 2.02E+07 1.57E+07 - - - 6.5058 0.9999 221125_WJC_METTL3_EV_vs_WT_F08.12529.12529.4 3.35E-07 18/96 R.QLSILVHPDK[136.11]NQDDADR[166.11].A sp|O75937|DNJC8_HUMAN 1 1980.9984 0.61 116601 12529 4 1981.001306 496.2569 DnaJ homolog subfamily C member 8 OS=Homo sapiens OX=9606 GN=DNAJC8 PE=1 SV=2 4.56 2350.5 - 761574 - - - 1.473 - 3.178 0.532 - 276 1 2 1 0.0029 17 0 0 0 8.06E+06 1.33E+07 - - - 4.2572 0.9994 221125_WJC_METTL3_EV_vs_WT_F08.12530.12530.3 0.000454 13/28 R.R[166.11]DYLHYIR[166.11].K "sp|P62280|RS11_HUMAN,tr|M0R1H5|M0R1H5_HUMAN,tr|M0QZC5|M0QZC5_HUMAN" 3 1154.61 0.07 116602 12530 3 1154.609962 385.8773 40S ribosomal protein S11 OS=Homo sapiens OX=9606 GN=RPS11 PE=1 SV=3 8.6 2350.6 - 455434 - - - -0.0043 - 2.388 0.22 - 351.8 1 2 0 0 8 0 0 0 3.03E+05 4.44E+06 - - - 3.7134 1 221125_WJC_METTL3_EV_vs_WT_F08.12532.12532.3 1.08E-10 19/76 K.AEEYTEETEER[166.11]EESTTGFDK[136.11].S "sp|Q9Y2W1|TR150_HUMAN,tr|A0A3B3ITZ9|A0A3B3ITZ9_HUMAN" 2 2397.0099 3.32 116604 12532 3 2397.002759 800.0106 Thyroid hormone receptor-associated protein 3 OS=Homo sapiens OX=9606 GN=THRAP3 PE=1 SV=2 3.93 2350.9 - 411810 - - - -2.962 - 3.365 0.728 - 404.3 1 2 1 -0.0071 20 0 0 0 2.24E+08 6.75E+07 - - - 9.5983 1 221125_WJC_METTL3_EV_vs_WT_F08.12537.12537.3 2.19E-11 23/64 R.TDEEGKDVPDHAVLEMK.A "sp|Q9BUJ2|HNRL1_HUMAN,tr|A0A0A0MRA5|A0A0A0MRA5_HUMAN,tr|M0R3F1|M0R3F1_HUMAN,tr|B7Z4B8|B7Z4B8_HUMAN" 4 1911.8884 1.71 116608 12537 3 1911.891066 638.3034 Heterogeneous nuclear ribonucleoprotein U-like protein 1 OS=Homo sapiens OX=9606 GN=HNRNPUL1 PE=1 SV=2 4.29 2351.5 - 3.60E+06 - - - 1.3902 - 4.458 0.715 - 795.1 1 2 1 0.0027 17 0 0 0 5.22E+07 3.05E+07 - - - 10.2869 0.9999 221125_WJC_METTL3_EV_vs_WT_F08.12538.12538.3 3.89E-08 24/88 K.QGVHAAGAAEAGPLASVPAQSAK.K sp|Q96H79|ZCCHL_HUMAN 1 2087.076 10.01 116609 12538 3 2087.084483 696.6993 Zinc finger CCCH-type antiviral protein 1-like OS=Homo sapiens OX=9606 GN=ZC3HAV1L PE=1 SV=2 6.75 2351.6 - 696596 - - - 4.0808 - 3.714 0.575 - 494.3 1 2 0 0.0085 23 0 0 0 1.44E+08 1.44E+07 - - - 8.0265 0.9998 221125_WJC_METTL3_EV_vs_WT_F08.12539.12539.4 3.43E-06 13/84 K.NLSDSEKELYIQHAK.E sp|Q00059|TFAM_HUMAN 1 1773.8897 1.23 116610 12539 4 1773.891879 444.4797 "Transcription factor A, mitochondrial OS=Homo sapiens OX=9606 GN=TFAM PE=1 SV=1" 5.45 2351.7 - 2.21E+06 - - - 1.2126 - 2.186 0.493 - 112.9 1 2 1 0.0022 15 0 0 0 2.12E+07 1.72E+07 - - - 3.7963 0.9999 221125_WJC_METTL3_EV_vs_WT_F08.12541.12541.3 2.40E-05 13/44 K.QQHVIETLIGK[136.11]K[136.11].Q "sp|P48643|TCPE_HUMAN,tr|E9PCA1|E9PCA1_HUMAN,tr|B7ZAR1|B7ZAR1_HUMAN,tr|E7ENZ3|E7ENZ3_HUMAN" 4 1408.8373 0.62 116612 12541 3 1408.838707 470.6197 T-complex protein 1 subunit epsilon OS=Homo sapiens OX=9606 GN=CCT5 PE=1 SV=1 8.6 2351.9 - 1.26E+06 - - - 0.9994 - 1.986 0.453 - 224.3 1 2 0 0.0014 12 0 0 0 5.40E+08 8.77E+08 - - - 5.4919 0.9604 221125_WJC_METTL3_EV_vs_WT_F08.12543.12543.3 0.00303 13/72 F.YTNPIAKPIPQTPESAGNK.H "sp|P52948|NUP98_HUMAN,tr|A0A3B3ITD8|A0A3B3ITD8_HUMAN" 2 2025.0531 2.89 116614 12543 3 2025.058447 676.025 Nuclear pore complex protein Nup98-Nup96 OS=Homo sapiens OX=9606 GN=NUP98 PE=1 SV=4 8.5 2352.1 - 404864 - - - 2.638 - 2.487 0.373 - 141.9 1 1 0 0.0053 19 0 0 0 1.62E+07 5.59E+06 - - - 4.9354 0.9454 221125_WJC_METTL3_EV_vs_WT_F08.12548.12548.3 3.28E-05 Sep-88 R.QPPPAPPEQADGNAPGPQPPPVR[166.11].L sp|Q12948|FOXC1_HUMAN 1 2323.1585 9.59 116619 12548 3 2324.155346 775.3934 Forkhead box protein C1 OS=Homo sapiens OX=9606 GN=FOXC1 PE=1 SV=3 4.37 2352.8 - 211090 - - - 429.1063 - 1.969 0.341 - 57 1 2 0 0.9969 23 0 0 0 7.57E+07 7.89E+06 - - - 3.6551 1 221125_WJC_METTL3_EV_vs_WT_F08.12553.12553.3 0.0144 23/76 K.AEEYTEETEEREESTTGFDK.S "sp|Q9Y2W1|TR150_HUMAN,tr|A0A3B3ITZ9|A0A3B3ITZ9_HUMAN" 2 2378.9874 3.32 116622 12553 3 2378.990101 794.0031 Thyroid hormone receptor-associated protein 3 OS=Homo sapiens OX=9606 GN=THRAP3 PE=1 SV=2 3.93 2353.4 - 9.98E+06 - - - 1.14 - 4.3 0.647 - 647.3 1 2 1 0.0027 20 0 0 0 2.24E+08 6.75E+07 - - - 9.2913 1 221125_WJC_METTL3_EV_vs_WT_F08.12555.12555.3 1.74E-06 19/44 K.QQHVIETLIGKK.Q "sp|P48643|TCPE_HUMAN,tr|E9PCA1|E9PCA1_HUMAN,tr|B7ZAR1|B7ZAR1_HUMAN,tr|E7ENZ3|E7ENZ3_HUMAN" 4 1392.8089 0.62 116624 12555 3 1392.811088 465.2769 T-complex protein 1 subunit epsilon OS=Homo sapiens OX=9606 GN=CCT5 PE=1 SV=1 8.6 2353.5 - 2.77E+06 - - - 1.5716 - 2.797 0.527 - 537.8 1 2 0 0.0022 12 0 0 0 5.40E+08 8.77E+08 - - - 7.2659 0.998 221125_WJC_METTL3_EV_vs_WT_F08.12556.12556.4 7.79E-05 17/66 K.TRLEQEIATYRR.L "sp|Q04695|K1C17_HUMAN,sp|P02533|K1C14_HUMAN,sp|P35900|K1C20_HUMAN,sp|P08779|K1C16_HUMAN,tr|A0A3B3IS58|A0A3B3IS58_HUMAN,tr|F5GWP8|F5GWP8_HUMAN" 6 1534.8216 32.26 116625 12556 4 1534.82283 384.7127 "Keratin, type I cytoskeletal 17 OS=Homo sapiens OX=9606 GN=KRT17 PE=1 SV=2" 8.41 2353.6 - 1.48E+06 - - - 0.8086 - 2.678 0.316 - 321.5 1 2 1 0.0012 12 0 0 0 6.27E+07 1.94E+06 - - - 2.3489 1 221125_WJC_METTL3_EV_vs_WT_F08.12558.12558.4 1.99E-10 19/84 R.FEPVHFVASSSKDER.Q sp|O15226|NKRF_HUMAN 1 1733.8373 1.27 116627 12558 4 1733.843133 434.4666 NF-kappa-B-repressing factor OS=Homo sapiens OX=9606 GN=NKRF PE=1 SV=2 5.45 2353.9 - 688721 - - - 3.3648 - 3.783 0.621 - 198.4 1 2 1 0.0058 15 0 0 0 4.44E+07 3.49E+07 - - - 5.1056 1 221125_WJC_METTL3_EV_vs_WT_F08.12560.12560.3 8.19E-12 16/68 R.HYEDGYPGGSDNYGSLSR[166.11].V "sp|O60716|CTND1_HUMAN,tr|A0A669KB62|A0A669KB62_HUMAN,tr|A0A669KB05|A0A669KB05_HUMAN,tr|C9JZR2|C9JZR2_HUMAN,tr|H0YC95|H0YC95_HUMAN" 5 1982.827 1.03 116629 12560 3 1982.830424 661.9496 Catenin delta-1 OS=Homo sapiens OX=9606 GN=CTNND1 PE=1 SV=1 4.54 2354.1 - 606777 - - - 1.7177 - 3.286 0.683 - 363.8 1 2 0 0.0034 18 0 0 0 1.53E+07 1.49E+07 - - - 9.1162 0.9999 221125_WJC_METTL3_EV_vs_WT_F08.12565.12565.3 3.40E-07 22/56 R.FEPVHFVASSSK[136.11]DER[166.11].Q sp|O15226|NKRF_HUMAN 1 1751.8598 1.16 116632 12565 3 1751.85948 584.9605 NF-kappa-B-repressing factor OS=Homo sapiens OX=9606 GN=NKRF PE=1 SV=2 5.45 2354.8 - 1.62E+06 - - - -0.165 - 3.523 0.562 - 856.1 1 2 1 -0.0003 15 0 0 0 6.09E+07 5.26E+07 - - - 8.0917 0.9999 221125_WJC_METTL3_EV_vs_WT_F08.12567.12567.4 3.01E-08 23/84 R.FEPVHFVASSSK[136.11]DER[166.11].Q sp|O15226|NKRF_HUMAN 1 1751.8598 1.27 116634 12567 4 1751.861361 438.9722 NF-kappa-B-repressing factor OS=Homo sapiens OX=9606 GN=NKRF PE=1 SV=2 5.45 2354.9 - 1.27E+06 - - - 0.9087 - 4.555 0.587 - 532.6 1 2 1 0.0016 15 0 0 0 4.44E+07 3.49E+07 - - - 4.8773 0.9817 221125_WJC_METTL3_EV_vs_WT_F08.12572.12572.3 0.278 Oct-48 K.WSFMNKPSDGRPK.Y "sp|P49821|NDUV1_HUMAN,tr|G3V0I5|G3V0I5_HUMAN,tr|E9PPR0|E9PPR0_HUMAN,tr|E9PMX3|E9PMX3_HUMAN,tr|E9PQP1|E9PQP1_HUMAN" 5 1548.7507 0.63 116639 12572 3 1548.752894 517.2575 "NADH dehydrogenase [ubiquinone] flavoprotein 1, mitochondrial OS=Homo sapiens OX=9606 GN=NDUFV1 PE=1 SV=4" 9.99 2355.6 - 367789 - - - 1.396 - 1.568 0.167 - 85.1 1 2 0 0.0022 13 0 0 0 2.33E+06 3.70E+06 - - - 1.6208 0.9996 221125_WJC_METTL3_EV_vs_WT_F08.12574.12574.4 0.000477 Nov-72 K.WSFMNKPSDGRPK.Y "sp|P49821|NDUV1_HUMAN,tr|G3V0I5|G3V0I5_HUMAN,tr|E9PPR0|E9PPR0_HUMAN,tr|E9PMX3|E9PMX3_HUMAN,tr|E9PQP1|E9PQP1_HUMAN" 5 1548.7507 1.28 116641 12574 4 1548.750188 388.195 "NADH dehydrogenase [ubiquinone] flavoprotein 1, mitochondrial OS=Homo sapiens OX=9606 GN=NDUFV1 PE=1 SV=4" 9.99 2355.9 - 245783 - - - -0.3513 - 1.977 0.339 - 110.8 1 2 0 -0.0005 13 0 0 0 4.54E+06 3.55E+06 - - - 2.4292 0.9998 221125_WJC_METTL3_EV_vs_WT_F08.12578.12578.3 0.00136 19/44 K.TRLEQEIATYRR.L "sp|Q04695|K1C17_HUMAN,sp|P02533|K1C14_HUMAN,sp|P35900|K1C20_HUMAN,sp|P08779|K1C16_HUMAN,tr|A0A3B3IS58|A0A3B3IS58_HUMAN,tr|F5GWP8|F5GWP8_HUMAN" 6 1534.8216 3297.65 116643 12578 3 1534.822482 512.6145 "Keratin, type I cytoskeletal 17 OS=Homo sapiens OX=9606 GN=KRT17 PE=1 SV=2" 8.41 2356.4 - 6.49E+06 - - - 0.5818 - 3.42 0.361 - 316.3 1 2 1 0.0009 12 0 0 0 1.53E+08 4.63E+04 - - - 5.9729 1 221125_WJC_METTL3_EV_vs_WT_F08.12584.12584.3 1.03E-08 19/72 K.VNPFRPGDSEPPPAPGAQR.A "sp|Q15942|ZYX_HUMAN,tr|H0Y2Y8|H0Y2Y8_HUMAN,tr|C9IZ41|C9IZ41_HUMAN" 3 1987.9864 9.04 116647 12584 3 1987.986487 663.6694 Zyxin OS=Homo sapiens OX=9606 GN=ZYX PE=1 SV=1 6.04 2357.1 - 751675 - - - 0.0322 - 3.379 0.573 - 430 1 2 0 0.0001 19 0 0 0 5.04E+07 5.57E+06 - - - 7.9197 0.9999 221125_WJC_METTL3_EV_vs_WT_F08.12589.12589.3 0.00202 16/44 K.NPHAPTIHFNYR[166.11].Y sp|P36551|HEM6_HUMAN 1 1475.7298 1.23 116649 12589 3 1475.729325 492.9172 "Oxygen-dependent coproporphyrinogen-III oxidase, mitochondrial OS=Homo sapiens OX=9606 GN=CPOX PE=1 SV=3" 8.76 2357.8 - 1.65E+06 - - - -0.2887 - 2.699 0.339 - 246.9 1 2 0 -0.0004 12 0 0 0 6.99E+07 5.70E+07 - - - 5.0715 0.9992 221125_WJC_METTL3_EV_vs_WT_F08.12591.12591.4 0.000387 11/108 K.FAGSAGWEGTESLK[136.11]K[136.11]PEDK[136.11].K "sp|Q13123|RED_HUMAN,tr|A0A0C4DGW5|A0A0C4DGW5_HUMAN" 2 2060.0277 1.53 116651 12591 4 2060.029874 516.0142 Protein Red OS=Homo sapiens OX=9606 GN=IK PE=1 SV=3 4.87 2358.1 - 697952 - - - 1.0626 - 2.341 0.381 - 54.6 1 2 1 0.0022 19 0 0 0 2.08E+07 1.37E+07 - - - 2.8294 0.9999 221125_WJC_METTL3_EV_vs_WT_F08.12592.12592.3 0.00293 15/76 R.AEAPGQPLKPPEGQEGFSQR.R sp|Q9UEG4|ZN629_HUMAN 1 2122.0443 0.64 116652 12592 3 2122.045314 708.3554 Zinc finger protein 629 OS=Homo sapiens OX=9606 GN=ZNF629 PE=1 SV=2 4.79 2358.2 - 617057 - - - 0.4628 - 2.422 0.385 - 172.4 1 2 0 0.001 20 0 0 0 1.49E+07 2.31E+07 - - - 4.9781 0.9999 221125_WJC_METTL3_EV_vs_WT_F08.12599.12599.3 0.00723 14/44 K.NPHAPTIHFNYR.Y sp|P36551|HEM6_HUMAN 1 1465.7215 1.24 116657 12599 3 1465.717853 489.5811 "Oxygen-dependent coproporphyrinogen-III oxidase, mitochondrial OS=Homo sapiens OX=9606 GN=CPOX PE=1 SV=3" 8.76 2359 - 1.68E+06 - - - -2.4752 - 2.543 0.413 - 236.5 1 2 0 -0.0036 12 0 0 0 7.09E+07 5.72E+07 - - - 5.7306 1 221125_WJC_METTL3_EV_vs_WT_F08.12603.12603.3 2.28E-09 19/56 R.FEPVHFVASSSKDER.Q sp|O15226|NKRF_HUMAN 1 1733.8373 1.16 116659 12603 3 1733.836908 578.953 NF-kappa-B-repressing factor OS=Homo sapiens OX=9606 GN=NKRF PE=1 SV=2 5.45 2359.5 - 2.72E+06 - - - -0.2255 - 3.157 0.608 - 488.4 1 2 1 -0.0004 15 0 0 0 6.09E+07 5.26E+07 - - - 8.3183 1 221125_WJC_METTL3_EV_vs_WT_F08.12606.12606.3 1.31E-05 17/64 R.NSIASC[160.03]ADEQPHIGNYR[166.11].L "sp|P27448|MARK3_HUMAN,tr|A0A7I2V3C6|A0A7I2V3C6_HUMAN,tr|A0A7I2V483|A0A7I2V483_HUMAN,tr|A0A7I2V3I9|A0A7I2V3I9_HUMAN,tr|A0A7I2V2J6|A0A7I2V2J6_HUMAN,tr|A0A7I2V3P5|A0A7I2V3P5_HUMAN,tr|A0A7I2V5H7|A0A7I2V5H7_HUMAN,tr|A0A7I2YQF4|A0A7I2YQF4_HUMAN,tr|A0A7I2YQF7|A0A7I2YQF7_HUMAN,tr|A0A7I2V4K8|A0A7I2V4K8_HUMAN,tr|A0A7I2YQ84|A0A7I2YQ84_HUMAN,tr|A0A7I2V3K2|A0A7I2V3K2_HUMAN,tr|A0A7I2V2U9|A0A7I2V2U9_HUMAN,tr|H0YNV4|H0YNV4_HUMAN,tr|A0A7I2V2N8|A0A7I2V2N8_HUMAN,tr|H0YJI9|H0YJI9_HUMAN,tr|A0A7I2V3X7|A0A7I2V3X7_HUMAN,tr|A0A7I2YQ91|A0A7I2YQ91_HUMAN,tr|A0A7I2V409|A0A7I2V409_HUMAN,tr|A0A7I2V4T2|A0A7I2V4T2_HUMAN,tr|A0A7I2V4L1|A0A7I2V4L1_HUMAN,tr|A0A7I2V549|A0A7I2V549_HUMAN,tr|A0A7I2V602|A0A7I2V602_HUMAN,tr|A0A7I2V4T5|A0A7I2V4T5_HUMAN,tr|A0A7I2YQJ7|A0A7I2YQJ7_HUMAN,tr|A0A7I2V3Q1|A0A7I2V3Q1_HUMAN,tr|A0A7I2V2I9|A0A7I2V2I9_HUMAN,tr|J3KNR0|J3KNR0_HUMAN" 28 1940.8674 0.79 116662 12606 3 1940.862009 647.9631 MAP\microtubule affinity-regulating kinase 3 OS=Homo sapiens OX=9606 GN=MARK3 PE=1 SV=5 5.32 2359.9 - 347072 - - - -2.8003 - 3.261 0.552 - 324.9 1 2 0 -0.0054 17 0 0 0 4.77E+07 6.06E+07 - - - 7.6789 0.9784 221125_WJC_METTL3_EV_vs_WT_F08.12634.12634.4 999 0/120 R.NC[160.03]C[160.03]GGC[160.03]GYGSGWSSGC[160.03]GYGC[160.03]G.Y sp|Q3LI59|KR212_HUMAN 1 2218.702 - 116673 12634 4 2218.704817 555.6828 Keratin-associated protein 21-2 OS=Homo sapiens OX=9606 GN=KRTAP21-2 PE=1 SV=2 5.49 2363.8 - 4.81E+06 - - - 1.2859 - 0.122 0.525 - 0 2 1 0 0.0029 21 0 0 0 - - - - - 2.8698 1 221125_WJC_METTL3_EV_vs_WT_F08.12685.12685.3 6.18E-10 18/60 V.HYEIDAC[160.03]MDSEAPGSK[136.11].D "sp|Q86U44|MTA70_HUMAN,tr|H0YFV6|H0YFV6_HUMAN" 2 1816.7487 0.02 116690 12685 3 1817.744289 606.5902 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 4.31 2370.7 - 1.89E+06 - - - 547.9784 - 3.115 0.678 - 346 1 1 0 0.9955 16 0 0 0 2.68E+06 1.51E+08 - - - 8.7387 1 221125_WJC_METTL3_EV_vs_WT_F08.12686.12686.4 1.64E-11 21/108 R.YGDSEFTVQSTTGHC[160.03]VHMR[166.11].G sp|P52597|HNRPF_HUMAN 1 2220.9556 0.77 116691 12686 4 2220.951146 556.2462 Heterogeneous nuclear ribonucleoprotein F OS=Homo sapiens OX=9606 GN=HNRNPF PE=1 SV=3 5.99 2370.7 - 4.35E+06 - - - -2.0086 - 3.834 0.705 - 276.3 1 2 0 -0.0045 19 0 0 0 1.12E+08 1.46E+08 - - - 5.8157 1 221125_WJC_METTL3_EV_vs_WT_F08.12692.12692.4 5.52E-12 26/96 K.K[136.11]MEDSVGC[160.03]LETAEEVK[136.11]R[166.11].K sp|P35579|MYH9_HUMAN 1 2005.9659 0.94 116697 12692 4 2005.959878 502.4988 Myosin-9 OS=Homo sapiens OX=9606 GN=MYH9 PE=1 SV=4 4.59 2371.3 - 1.07E+06 - - - -3.0005 - 4.481 0.647 - 965.7 1 2 0 -0.006 17 0 0 0 1.86E+07 1.98E+07 - - - 5.3766 1 221125_WJC_METTL3_EV_vs_WT_F08.12700.12700.4 2.50E-08 24/108 R.YGDSEFTVQSTTGHC[160.03]VHMR.G sp|P52597|HNRPF_HUMAN 1 2210.9473 0.77 116703 12700 4 2210.944316 553.7441 Heterogeneous nuclear ribonucleoprotein F OS=Homo sapiens OX=9606 GN=HNRNPF PE=1 SV=3 5.99 2372.1 - 4.38E+06 - - - -1.3664 - 3.281 0.561 - 477.5 1 2 0 -0.003 19 0 0 0 1.12E+08 1.46E+08 - - - 4.51 1 221125_WJC_METTL3_EV_vs_WT_F08.12701.12701.4 1.05E-10 25/96 K.KMEDSVGC[160.03]LETAEEVKR.K sp|P35579|MYH9_HUMAN 1 1979.9292 0.83 116704 12701 4 1979.926119 495.9896 Myosin-9 OS=Homo sapiens OX=9606 GN=MYH9 PE=1 SV=4 4.59 2372.3 - 1.22E+06 - - - -1.5698 - 4.043 0.636 - 933.5 1 2 0 -0.0031 17 0 0 0 1.88E+07 2.27E+07 - - - 5.2459 1 221125_WJC_METTL3_EV_vs_WT_F08.12703.12703.3 2.16E-16 22/64 K.KMEDSVGC[160.03]LETAEEVKR.K sp|P35579|MYH9_HUMAN 1 1979.9292 2.7 116706 12703 3 1979.926308 660.9837 Myosin-9 OS=Homo sapiens OX=9606 GN=MYH9 PE=1 SV=4 4.59 2372.5 - 877701 - - - -1.4743 - 4.305 0.718 - 841.5 1 2 0 -0.0029 17 0 0 0 3.68E+07 1.36E+07 - - - 10.232 1 221125_WJC_METTL3_EV_vs_WT_F08.12704.12704.3 2.32E-12 23/88 R.QPPPAPPEQADGNAPGPQPPPVR.L sp|Q12948|FOXC1_HUMAN 1 2313.1502 9.28 116707 12704 3 2313.151282 772.0573 Forkhead box protein C1 OS=Homo sapiens OX=9606 GN=FOXC1 PE=1 SV=3 4.37 2372.7 - 797889 - - - 0.4704 - 3.88 0.674 - 317.3 1 2 0 0.0011 23 0 0 0 9.47E+07 1.02E+07 - - - 9.2348 1 221125_WJC_METTL3_EV_vs_WT_F08.12705.12705.3 7.35E-13 21/64 K.K[136.11]MEDSVGC[160.03]LETAEEVK[136.11]R[166.11].K sp|P35579|MYH9_HUMAN 1 2005.9659 2.44 116708 12705 3 2005.960862 669.6626 Myosin-9 OS=Homo sapiens OX=9606 GN=MYH9 PE=1 SV=4 4.59 2372.8 - 711221 - - - -2.51 - 4.142 0.64 - 679.8 1 2 0 -0.005 17 0 0 0 3.32E+07 1.36E+07 - - - 9.2643 1 221125_WJC_METTL3_EV_vs_WT_F08.12711.12711.3 1.01E-11 27/72 R.YGDSEFTVQSTTGHC[160.03]VHMR[166.11].G sp|P52597|HNRPF_HUMAN 1 2220.9556 0.63 116712 12711 3 2220.946855 741.3258 Heterogeneous nuclear ribonucleoprotein F OS=Homo sapiens OX=9606 GN=HNRNPF PE=1 SV=3 5.99 2373.6 - 2.41E+06 - - - -3.9406 - 4.95 0.741 - 1507.2 1 2 0 -0.0088 19 0 0 0 1.98E+07 3.16E+07 - - - 10.7284 0.9999 221125_WJC_METTL3_EV_vs_WT_F08.12714.12714.4 9.96E-07 18/90 K.IFVGGIKEDTEEHHLR.D "sp|Q32P51|RA1L2_HUMAN,sp|P09651|ROA1_HUMAN,sp|P22626|ROA2_HUMAN,tr|A0A7I2YQN4|A0A7I2YQN4_HUMAN,tr|A0A7I2YQX9|A0A7I2YQX9_HUMAN,tr|A0A7I2V4N0|A0A7I2V4N0_HUMAN,tr|A0A024RA28|A0A024RA28_HUMAN,tr|A0A7I2V4N1|A0A7I2V4N1_HUMAN,tr|A0A7I2V4I6|A0A7I2V4I6_HUMAN,tr|F8VZ49|F8VZ49_HUMAN,tr|A0A7I2V3R8|A0A7I2V3R8_HUMAN,tr|A0A087WUI2|A0A087WUI2_HUMAN,tr|A0A7I2V4S4|A0A7I2V4S4_HUMAN,tr|F8VTQ5|F8VTQ5_HUMAN,tr|F8W6I7|F8W6I7_HUMAN,tr|A0A7I2V2L6|A0A7I2V2L6_HUMAN,tr|A0A7I2V323|A0A7I2V323_HUMAN,tr|A0A7I2V3W0|A0A7I2V3W0_HUMAN,tr|A0A7I2V5U9|A0A7I2V5U9_HUMAN,tr|A0A2R8Y4L2|A0A2R8Y4L2_HUMAN,tr|A0A7I2V3P1|A0A7I2V3P1_HUMAN,tr|A0A7I2V3P7|A0A7I2V3P7_HUMAN" 22 1878.9588 1.09 116715 12714 4 1878.958996 470.747 Heterogeneous nuclear ribonucleoprotein A1-like 2 OS=Homo sapiens OX=9606 GN=HNRNPA1L2 PE=2 SV=2 5.36 2373.9 - 975773 - - - 0.0985 - 3.654 0.495 - 315.3 1 2 1 0.0002 16 0 0 0 1.55E+07 1.42E+07 - - - 3.9909 0.9969 221125_WJC_METTL3_EV_vs_WT_F08.12719.12719.3 6.61E-06 13/60 K.FKDDSNHTIGVEFGSK.L sp|P20338|RAB4A_HUMAN 1 1779.8428 999 116719 12719 3 1779.848075 594.2882 Ras-related protein Rab-4A OS=Homo sapiens OX=9606 GN=RAB4A PE=1 SV=3 5.38 2374.4 - 867963 - - - 2.9761 - 2.465 0.341 - 139 1 2 1 0.0053 16 0 0 0 9.37E+06 0.00E+00 - - - 4.6552 1 221125_WJC_METTL3_EV_vs_WT_F08.12723.12723.3 8.90E-09 19/80 R.TVPGATTTSSAATETMENVK[136.11]K[136.11].C sp|O00268|TAF4_HUMAN 1 2139.07 1.55 116722 12723 3 2139.066763 714.0306 Transcription initiation factor TFIID subunit 4 OS=Homo sapiens OX=9606 GN=TAF4 PE=1 SV=2 5.81 2374.8 - 1.70E+06 - - - -1.5198 - 3.194 0.556 - 253.7 1 2 0 -0.0033 21 0 0 0 3.39E+07 2.19E+07 - - - 7.5221 1 221125_WJC_METTL3_EV_vs_WT_F08.12724.12724.3 5.81E-10 28/72 R.YGDSEFTVQSTTGHC[160.03]VHMR.G sp|P52597|HNRPF_HUMAN 1 2210.9473 0.62 116723 12724 3 2210.952638 737.9897 Heterogeneous nuclear ribonucleoprotein F OS=Homo sapiens OX=9606 GN=HNRNPF PE=1 SV=3 5.99 2374.9 - 1.51E+06 - - - 2.3976 - 4.818 0.621 - 1667 1 2 0 0.0053 19 0 0 0 1.93E+07 3.13E+07 - - - 9.325 0.9926 221125_WJC_METTL3_EV_vs_WT_F08.12726.12726.4 0.162 Sep-90 R.MESSINHISQTVDIHK.E "sp|Q8IZP0|ABI1_HUMAN,sp|Q9NYB9|ABI2_HUMAN,tr|A0A7D9NKC8|A0A7D9NKC8_HUMAN,tr|A0A0C4DG21|A0A0C4DG21_HUMAN,tr|A0A0A0MRT6|A0A0A0MRT6_HUMAN,tr|E7EW77|E7EW77_HUMAN,tr|E7EP65|E7EP65_HUMAN,tr|F8WAL6|F8WAL6_HUMAN,tr|B6VEX4|B6VEX4_HUMAN,tr|E9PEZ7|E9PEZ7_HUMAN" 10 1837.8992 1.31 116725 12726 4 1837.898358 460.4821 Abl interactor 1 OS=Homo sapiens OX=9606 GN=ABI1 PE=1 SV=4 5.95 2375.1 - 675210 - - - -0.4837 - 1.739 0.213 - 59.5 1 2 0 -0.0009 16 0 0 0 4.58E+06 3.51E+06 - - - 1.2746 1 221125_WJC_METTL3_EV_vs_WT_F08.12727.12727.2 3.01E-11 21/30 V.HYEIDAC[160.03]MDSEAPGSK[136.11].D "sp|Q86U44|MTA70_HUMAN,tr|H0YFV6|H0YFV6_HUMAN" 2 1816.7487 0.001 116726 12727 2 1816.746014 909.3817 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 4.31 2375.3 - 493043 - - - -1.506 - 4.351 0.797 - 992.3 1 1 0 -0.0027 16 0 0 0 0.00E+00 9.50E+06 - - - 8.5418 1 221125_WJC_METTL3_EV_vs_WT_F08.12728.12728.2 1.44E-09 16/36 F.SSC[160.03]GGGGGSFGAGGGFGSR.S sp|P04264|K2C1_HUMAN 1 1617.659 999 116727 12728 2 1617.65434 809.8368 "Keratin, type II cytoskeletal 1 OS=Homo sapiens OX=9606 GN=KRT1 PE=1 SV=6" 7.96 2375.4 - 372817 - - - -2.8912 - 3.279 0.721 - 691.1 1 1 0 -0.0047 19 0 0 0 5.12E+06 0.00E+00 - - - 7.2845 1 221125_WJC_METTL3_EV_vs_WT_F08.12734.12734.4 4.53E-11 23/90 K.IFVGGIK[136.11]EDTEEHHLR[166.11].D "sp|Q32P51|RA1L2_HUMAN,sp|P09651|ROA1_HUMAN,sp|P22626|ROA2_HUMAN,tr|A0A7I2YQN4|A0A7I2YQN4_HUMAN,tr|A0A7I2YQX9|A0A7I2YQX9_HUMAN,tr|A0A7I2V4N0|A0A7I2V4N0_HUMAN,tr|A0A024RA28|A0A024RA28_HUMAN,tr|A0A7I2V4N1|A0A7I2V4N1_HUMAN,tr|A0A7I2V4I6|A0A7I2V4I6_HUMAN,tr|F8VZ49|F8VZ49_HUMAN,tr|A0A7I2V3R8|A0A7I2V3R8_HUMAN,tr|A0A087WUI2|A0A087WUI2_HUMAN,tr|A0A7I2V4S4|A0A7I2V4S4_HUMAN,tr|F8VTQ5|F8VTQ5_HUMAN,tr|F8W6I7|F8W6I7_HUMAN,tr|A0A7I2V2L6|A0A7I2V2L6_HUMAN,tr|A0A7I2V323|A0A7I2V323_HUMAN,tr|A0A7I2V3W0|A0A7I2V3W0_HUMAN,tr|A0A7I2V5U9|A0A7I2V5U9_HUMAN,tr|A0A2R8Y4L2|A0A2R8Y4L2_HUMAN,tr|A0A7I2V3P1|A0A7I2V3P1_HUMAN,tr|A0A7I2V3P7|A0A7I2V3P7_HUMAN" 22 1896.9813 1.32 116731 12734 4 1896.977788 475.2526 Heterogeneous nuclear ribonucleoprotein A1-like 2 OS=Homo sapiens OX=9606 GN=HNRNPA1L2 PE=2 SV=2 5.36 2376.1 - 725370 - - - -1.8413 - 4.141 0.656 - 616.6 1 2 1 -0.0035 16 0 0 0 1.14E+07 8.60E+06 - - - 5.4354 0.9991 221125_WJC_METTL3_EV_vs_WT_F08.12735.12735.3 0.00124 Oct-40 K.LKVSELKEELK.K "sp|Q00839|HNRPU_HUMAN,tr|A0A1W2PPS1|A0A1W2PPS1_HUMAN,tr|A0A1X7SBS1|A0A1X7SBS1_HUMAN" 3 1314.7759 0.95 116732 12735 3 1314.77274 439.2659 Heterogeneous nuclear ribonucleoprotein U OS=Homo sapiens OX=9606 GN=HNRNPU PE=1 SV=6 6.23 2376.2 - 444301 - - - -2.3791 - 2.312 0.399 - 74.9 1 2 2 -0.0031 11 0 0 0 6.57E+06 6.91E+06 - - - 5.3685 0.9998 221125_WJC_METTL3_EV_vs_WT_F08.12736.12736.3 0.00168 14/40 K.LK[136.11]VSELK[136.11]EELK[136.11].K "sp|Q00839|HNRPU_HUMAN,tr|A0A1W2PPS1|A0A1W2PPS1_HUMAN,tr|A0A1X7SBS1|A0A1X7SBS1_HUMAN" 3 1338.8185 0.95 116733 12736 3 1338.81625 447.2801 Heterogeneous nuclear ribonucleoprotein U OS=Homo sapiens OX=9606 GN=HNRNPU PE=1 SV=6 6.23 2376.3 - 822207 - - - -1.6567 - 2.715 0.476 - 160.7 1 2 2 -0.0022 11 0 0 0 6.57E+06 6.91E+06 - - - 6.6837 0.9999 221125_WJC_METTL3_EV_vs_WT_F08.12737.12737.4 2.81E-10 16/102 R.VLGTEAVQDPTK[136.11]VEAHVR[166.11].A sp|O43395|PRPF3_HUMAN 1 1966.0603 2.31 116734 12737 4 1966.058558 492.5223 U4\U6 small nuclear ribonucleoprotein Prp3 OS=Homo sapiens OX=9606 GN=PRPF3 PE=1 SV=2 5.44 2376.5 - 457119 - - - -0.8657 - 3.309 0.522 - 220.1 1 2 1 -0.0017 18 0 0 0 3.10E+07 1.34E+07 - - - 4.1789 1 221125_WJC_METTL3_EV_vs_WT_F08.12738.12738.3 0.000292 15/40 R.SLGTADVHFER[166.11].K "sp|Q86V81|THOC4_HUMAN,tr|E9PB61|E9PB61_HUMAN" 2 1240.6076 0.75 116735 12738 3 1240.607695 414.5431 THO complex subunit 4 OS=Homo sapiens OX=9606 GN=ALYREF PE=1 SV=3 5.3 2376.6 - 340345 - - - 0.1008 - 2.836 0.456 - 303.6 1 2 0 0.0001 11 0 0 0 1.01E+07 1.36E+07 - - - 6.5852 0.9991 221125_WJC_METTL3_EV_vs_WT_F08.12746.12746.4 0.00376 15/78 K.DRLLASTLVHSVKK.E "sp|Q9NYF8|BCLF1_HUMAN,tr|E9PKI6|E9PKI6_HUMAN,tr|A0A1W2PQ43|A0A1W2PQ43_HUMAN,tr|E9PK91|E9PK91_HUMAN,tr|E9PJA7|E9PJA7_HUMAN,tr|E9PK09|E9PK09_HUMAN,tr|E9PQN2|E9PQN2_HUMAN" 7 1565.9253 1.6 116741 12746 4 1565.925977 392.4886 Bcl-2-associated transcription factor 1 OS=Homo sapiens OX=9606 GN=BCLAF1 PE=1 SV=2 9.99 2377.5 - 558188 - - - 0.4157 - 2.588 0.363 - 172.1 1 2 1 0.0007 14 0 0 0 4.12E+07 2.57E+07 - - - 2.7314 0.9999 221125_WJC_METTL3_EV_vs_WT_F08.12750.12750.3 0.000329 13/64 K.VSDEPPQLPEPQPR[166.11]PGR[166.11].L sp|O94761|RECQ4_HUMAN 1 1917.9812 2.33 116745 12750 3 1917.981822 640.3343 ATP-dependent DNA helicase Q4 OS=Homo sapiens OX=9606 GN=RECQL4 PE=1 SV=2 4.68 2378 - 177535 - - - 0.3425 - 2.472 0.421 - 189.5 1 2 0 0.0007 17 0 0 0 6.27E+06 2.69E+06 - - - 5.5199 0.9736 221125_WJC_METTL3_EV_vs_WT_F08.12752.12752.4 0.0062 13/78 R.K[136.11]IELFGR[166.11]PHNVQPN.W sp|Q86U44|MTA70_HUMAN 1 1665.907 0.01 116746 12752 4 1665.90569 417.484 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 8.75 2378.3 - 1.41E+06 - - - -0.7828 - 2.213 0.371 - 166.2 1 1 0 -0.0013 14 0 0 0 1.59E+06 2.07E+08 - - - 2.7439 0.9998 221125_WJC_METTL3_EV_vs_WT_F08.12755.12755.3 0.000431 Nov-36 R.DENWDK[136.11]EIEK[136.11].M sp|Q96A49|SYAP1_HUMAN 1 1320.6169 1.15 116748 12755 3 1320.615749 441.2129 Synapse-associated protein 1 OS=Homo sapiens OX=9606 GN=SYAP1 PE=1 SV=1 4.18 2378.6 - 493148 - - - -0.842 - 2.065 0.515 - 186 1 2 1 -0.0011 10 0 0 0 8.55E+06 7.42E+06 - - - 6.3991 1 221125_WJC_METTL3_EV_vs_WT_F08.12757.12757.3 0.000105 14/40 R.SLGTADVHFER.K "sp|Q86V81|THOC4_HUMAN,tr|E9PB61|E9PB61_HUMAN" 2 1230.5993 0.75 116750 12757 3 1230.598834 411.207 THO complex subunit 4 OS=Homo sapiens OX=9606 GN=ALYREF PE=1 SV=3 5.3 2378.8 - 810715 - - - -0.3787 - 2.619 0.471 - 235.3 1 2 0 -0.0005 11 0 0 0 1.01E+07 1.36E+07 - - - 6.5262 1 221125_WJC_METTL3_EV_vs_WT_F08.12758.12758.3 1.45E-11 19/68 R.GGPPC[160.03]KPPAPEDEDEAWR.Q sp|P48634|PRC2A_HUMAN 1 2006.8792 2.06 116751 12758 3 2006.878122 669.967 Protein PRRC2A OS=Homo sapiens OX=9606 GN=PRRC2A PE=1 SV=3 4.18 2379 - 534320 - - - -0.5571 - 3.491 0.678 - 451.3 1 2 0 -0.0011 18 0 0 0 1.55E+07 7.51E+06 - - - 9.2118 0.9998 221125_WJC_METTL3_EV_vs_WT_F08.12759.12759.3 0.00025 15/52 K.DRLLASTLVHSVKK.E "sp|Q9NYF8|BCLF1_HUMAN,tr|E9PKI6|E9PKI6_HUMAN,tr|A0A1W2PQ43|A0A1W2PQ43_HUMAN,tr|E9PK91|E9PK91_HUMAN,tr|E9PJA7|E9PJA7_HUMAN,tr|E9PK09|E9PK09_HUMAN,tr|E9PQN2|E9PQN2_HUMAN" 7 1565.9253 1.52 116752 12759 3 1565.927304 522.9824 Bcl-2-associated transcription factor 1 OS=Homo sapiens OX=9606 GN=BCLAF1 PE=1 SV=2 9.99 2379.1 - 518563 - - - 1.2632 - 3.104 0.408 - 266.6 1 2 1 0.002 14 0 0 0 1.79E+07 1.18E+07 - - - 6.0984 1 221125_WJC_METTL3_EV_vs_WT_F08.12761.12761.3 3.54 21/56 K.K[136.11]FEEFQTDMAAHEER[166.11].V "sp|Q13813|SPTN1_HUMAN,tr|A0A0D9SF54|A0A0D9SF54_HUMAN,tr|A0A0D9SGF6|A0A0D9SGF6_HUMAN" 3 1884.8431 1.51 116754 12761 3 1884.843919 629.2883 "Spectrin alpha chain, non-erythrocytic 1 OS=Homo sapiens OX=9606 GN=SPTAN1 PE=1 SV=3" 4.57 2379.4 - 459938 - - - 0.4175 - 4.375 0.621 - 806.3 1 2 0 0.0008 15 0 0 0 1.11E+07 7.32E+06 - - - 9.3145 1 221125_WJC_METTL3_EV_vs_WT_F08.12765.12765.3 1.31E-09 15/52 R.DDSFFGETSHNYHK[136.11].F "sp|P43243|MATR3_HUMAN,tr|A8MXP9|A8MXP9_HUMAN,tr|D6R991|D6R991_HUMAN,tr|A0A0R4J2E8|A0A0R4J2E8_HUMAN,tr|H0Y8T4|H0Y8T4_HUMAN,tr|D6REM6|D6REM6_HUMAN" 6 1690.7103 1.33 116758 12765 3 1690.708791 564.5774 Matrin-3 OS=Homo sapiens OX=9606 GN=MATR3 PE=1 SV=2 5.21 2379.9 - 227533 - - - -0.9008 - 3.191 0.681 - 204.7 1 2 0 -0.0015 14 0 0 0 1.84E+07 1.39E+07 - - - 9.2157 1 221125_WJC_METTL3_EV_vs_WT_F08.12768.12768.4 5.15E-09 19/114 K.VVTTNYK[136.11]PVANHQYNIEYER[166.11].K sp|P13984|T2FB_HUMAN 1 2455.2251 1.18 116759 12768 4 2455.224245 614.8135 General transcription factor IIF subunit 2 OS=Homo sapiens OX=9606 GN=GTF2F2 PE=1 SV=2 6.72 2380.3 - 2.39E+06 - - - -0.3454 - 3.057 0.591 - 192.8 1 2 0 -0.0008 20 0 0 0 3.43E+07 2.92E+07 - - - 4.7434 0.9999 221125_WJC_METTL3_EV_vs_WT_F08.12769.12769.4 1.18E-06 19/78 K.DR[166.11]LLASTLVHSVK[136.11]K[136.11].E "sp|Q9NYF8|BCLF1_HUMAN,tr|E9PKI6|E9PKI6_HUMAN,tr|A0A1W2PQ43|A0A1W2PQ43_HUMAN,tr|E9PK91|E9PK91_HUMAN,tr|E9PJA7|E9PJA7_HUMAN,tr|E9PK09|E9PK09_HUMAN,tr|E9PQN2|E9PQN2_HUMAN" 7 1591.962 1.6 116760 12769 4 1591.960544 398.9978 Bcl-2-associated transcription factor 1 OS=Homo sapiens OX=9606 GN=BCLAF1 PE=1 SV=2 9.99 2380.4 - 1.23E+06 - - - -0.9121 - 3.204 0.572 - 452.3 1 2 1 -0.0015 14 0 0 0 4.12E+07 2.57E+07 - - - 4.6281 0.9999 221125_WJC_METTL3_EV_vs_WT_F08.12770.12770.4 1.51E-08 19/102 R.VLGTEAVQDPTKVEAHVR.A sp|O43395|PRPF3_HUMAN 1 1948.0378 2.31 116761 12770 4 1948.03833 488.0167 U4\U6 small nuclear ribonucleoprotein Prp3 OS=Homo sapiens OX=9606 GN=PRPF3 PE=1 SV=2 5.44 2380.5 - 1.79E+06 - - - 0.2772 - 3.365 0.582 - 369.8 1 2 1 0.0005 18 0 0 0 3.10E+07 1.34E+07 - - - 4.7072 1 221125_WJC_METTL3_EV_vs_WT_F08.12772.12772.3 2.22E-12 18/64 R.DHANYEEDENGDITPIK.A "sp|Q99547|MPH6_HUMAN,tr|H3BNT4|H3BNT4_HUMAN,tr|H3BSB3|H3BSB3_HUMAN" 3 1958.8494 1.44 116763 12772 3 1958.843931 653.9571 M-phase phosphoprotein 6 OS=Homo sapiens OX=9606 GN=MPHOSPH6 PE=1 SV=2 4.01 2380.7 - 614762 - - - -2.7817 - 3.482 0.761 - 502.4 1 2 0 -0.0054 17 0 0 0 1.13E+07 7.89E+06 - - - 10.1747 1 221125_WJC_METTL3_EV_vs_WT_F08.12773.12773.4 2.62E-07 18/84 K.KFEEFQTDMAAHEER.V "sp|Q13813|SPTN1_HUMAN,tr|A0A0D9SF54|A0A0D9SF54_HUMAN,tr|A0A0D9SGF6|A0A0D9SGF6_HUMAN" 3 1866.8207 0.93 116764 12773 4 1866.82281 467.7124 "Spectrin alpha chain, non-erythrocytic 1 OS=Homo sapiens OX=9606 GN=SPTAN1 PE=1 SV=3" 4.57 2380.8 - 599416 - - - 1.1506 - 3.849 0.551 - 445.2 1 2 0 0.0021 15 0 0 0 6.61E+06 7.10E+06 - - - 4.5036 1 221125_WJC_METTL3_EV_vs_WT_F08.12774.12774.3 1.03E-11 18/76 K.VVTTNYK[136.11]PVANHQYNIEYER[166.11].K sp|P13984|T2FB_HUMAN 1 2455.2251 1.33 116765 12774 3 2455.22331 819.4156 General transcription factor IIF subunit 2 OS=Homo sapiens OX=9606 GN=GTF2F2 PE=1 SV=2 6.72 2381 - 561507 - - - -0.7262 - 3.22 0.651 - 283.2 1 2 0 -0.0018 20 0 0 0 7.53E+06 5.68E+06 - - - 8.6345 1 221125_WJC_METTL3_EV_vs_WT_F08.12775.12775.3 2.03E-15 15/64 R.DHANYEEDENGDITPIK[136.11].A "sp|Q99547|MPH6_HUMAN,tr|H3BNT4|H3BNT4_HUMAN,tr|H3BSB3|H3BSB3_HUMAN" 3 1966.8636 1.44 116766 12775 3 1966.863559 656.6285 M-phase phosphoprotein 6 OS=Homo sapiens OX=9606 GN=MPHOSPH6 PE=1 SV=2 4.01 2381.1 - 557048 - - - -0.0107 - 3.018 0.706 - 347.7 1 2 0 0 17 0 0 0 1.13E+07 7.89E+06 - - - 9.2017 1 221125_WJC_METTL3_EV_vs_WT_F08.12777.12777.3 3.00E-05 16/52 R.DDSFFGETSHNYHK.F "sp|P43243|MATR3_HUMAN,tr|A8MXP9|A8MXP9_HUMAN,tr|D6R991|D6R991_HUMAN,tr|A0A0R4J2E8|A0A0R4J2E8_HUMAN,tr|H0Y8T4|H0Y8T4_HUMAN,tr|D6REM6|D6REM6_HUMAN" 6 1682.6961 1.33 116768 12777 3 1682.69692 561.906 Matrin-3 OS=Homo sapiens OX=9606 GN=MATR3 PE=1 SV=2 5.21 2381.4 - 526671 - - - 0.479 - 3.177 0.625 - 299.5 1 2 0 0.0008 14 0 0 0 1.84E+07 1.39E+07 - - - 8.5798 1 221125_WJC_METTL3_EV_vs_WT_F08.12778.12778.4 7.77E-07 13/78 R.DDSFFGETSHNYHK[136.11].F "sp|P43243|MATR3_HUMAN,tr|A8MXP9|A8MXP9_HUMAN,tr|D6R991|D6R991_HUMAN,tr|A0A0R4J2E8|A0A0R4J2E8_HUMAN,tr|H0Y8T4|H0Y8T4_HUMAN,tr|D6REM6|D6REM6_HUMAN" 6 1690.7103 1.5 116769 12778 4 1690.711707 423.6849 Matrin-3 OS=Homo sapiens OX=9606 GN=MATR3 PE=1 SV=2 5.21 2381.5 - 453099 - - - 0.8239 - 1.854 0.642 - 76.9 1 2 0 0.0014 14 0 0 0 1.53E+07 1.02E+07 - - - 5.0383 1 221125_WJC_METTL3_EV_vs_WT_F08.12784.12784.4 0.000312 21/114 K.VVTTNYKPVANHQYNIEYER.K sp|P13984|T2FB_HUMAN 1 2437.2026 1.18 116773 12784 4 2437.20426 610.3079 General transcription factor IIF subunit 2 OS=Homo sapiens OX=9606 GN=GTF2F2 PE=1 SV=2 6.72 2382.3 - 4.92E+06 - - - 0.6717 - 3.082 0.533 - 268.8 1 2 0 0.0016 20 0 0 0 3.43E+07 2.92E+07 - - - 4.2411 1 221125_WJC_METTL3_EV_vs_WT_F08.12785.12785.3 1.44E-15 21/60 K.HNMDIGTWDNKGPVAK.A sp|Q9Y5A9|YTHD2_HUMAN 1 1781.8519 1.58 116774 12785 3 1781.853675 594.9579 YTH domain-containing family protein 2 OS=Homo sapiens OX=9606 GN=YTHDF2 PE=1 SV=2 6.75 2382.4 - 2.22E+06 - - - 0.9945 - 4.154 0.746 - 636.8 1 2 1 0.0018 16 0 0 0 1.38E+08 8.73E+07 - - - 10.5106 0.8978 221125_WJC_METTL3_EV_vs_WT_F08.12786.12786.3 0.00154 Dec-48 K.EKKEEQVISLGPQ.V "sp|P62263|RS14_HUMAN,tr|A0A2R8Y811|A0A2R8Y811_HUMAN,tr|E5RH77|E5RH77_HUMAN" 3 1483.7882 1.43 116775 12786 3 1483.789042 495.6034 40S ribosomal protein S14 OS=Homo sapiens OX=9606 GN=RPS14 PE=1 SV=3 4.79 2382.5 - 1.21E+06 - - - 0.552 - 2.258 0.33 - 162 1 1 1 0.0008 13 0 0 0 5.28E+07 3.69E+07 - - - 4.4272 1 221125_WJC_METTL3_EV_vs_WT_F08.12787.12787.3 9.98E-17 22/56 K.KFEEFQTDMAAHEER.V "sp|Q13813|SPTN1_HUMAN,tr|A0A0D9SF54|A0A0D9SF54_HUMAN,tr|A0A0D9SGF6|A0A0D9SGF6_HUMAN" 3 1866.8207 1.51 116776 12787 3 1866.823022 623.2808 "Spectrin alpha chain, non-erythrocytic 1 OS=Homo sapiens OX=9606 GN=SPTAN1 PE=1 SV=3" 4.57 2382.6 - 924046 - - - 1.2642 - 4.517 0.688 - 895.7 1 2 0 0.0024 15 0 0 0 1.11E+07 7.32E+06 - - - 10.1444 0.9999 221125_WJC_METTL3_EV_vs_WT_F08.12789.12789.3 9.81E-09 23/68 R.VLGTEAVQDPTKVEAHVR.A sp|O43395|PRPF3_HUMAN 1 1948.0378 3.33 116778 12789 3 1948.038388 650.3532 U4\U6 small nuclear ribonucleoprotein Prp3 OS=Homo sapiens OX=9606 GN=PRPF3 PE=1 SV=2 5.44 2382.8 - 831454 - - - 0.307 - 3.775 0.56 - 745.6 1 2 1 0.0006 18 0 0 0 1.22E+07 3.67E+06 - - - 8.0911 1 221125_WJC_METTL3_EV_vs_WT_F08.12790.12790.3 7.47E-09 24/76 K.VVTTNYKPVANHQYNIEYER.K sp|P13984|T2FB_HUMAN 1 2437.2026 1.33 116779 12790 3 2437.202957 813.4082 General transcription factor IIF subunit 2 OS=Homo sapiens OX=9606 GN=GTF2F2 PE=1 SV=2 6.72 2382.9 - 750778 - - - 0.137 - 4.106 0.689 - 744.3 1 2 0 0.0003 20 0 0 0 7.53E+06 5.68E+06 - - - 9.6482 1 221125_WJC_METTL3_EV_vs_WT_F08.12791.12791.3 1.47E-07 18/52 K.DR[166.11]LLASTLVHSVK[136.11]K[136.11].E "sp|Q9NYF8|BCLF1_HUMAN,tr|E9PKI6|E9PKI6_HUMAN,tr|A0A1W2PQ43|A0A1W2PQ43_HUMAN,tr|E9PK91|E9PK91_HUMAN,tr|E9PJA7|E9PJA7_HUMAN,tr|E9PK09|E9PK09_HUMAN,tr|E9PQN2|E9PQN2_HUMAN" 7 1591.962 1.49 116780 12791 3 1591.962362 531.6613 Bcl-2-associated transcription factor 1 OS=Homo sapiens OX=9606 GN=BCLAF1 PE=1 SV=2 9.99 2383.1 - 646630 - - - 0.2299 - 3.376 0.599 - 400.6 1 2 1 0.0004 14 0 0 0 1.79E+07 1.20E+07 - - - 8.4516 0.9999 221125_WJC_METTL3_EV_vs_WT_F08.12793.12793.4 7.34E-10 18/90 K.HNMDIGTWDNKGPVAK.A sp|Q9Y5A9|YTHD2_HUMAN 1 1781.8519 69.5 116782 12793 4 1781.850427 446.4703 YTH domain-containing family protein 2 OS=Homo sapiens OX=9606 GN=YTHDF2 PE=1 SV=2 6.75 2383.3 - 499247 - - - -0.8284 - 3.245 0.582 - 258.1 1 2 1 -0.0015 16 0 0 0 2.89E+07 4.16E+05 - - - 4.706 0.9996 221125_WJC_METTL3_EV_vs_WT_F08.12802.12802.3 7.67E-05 16/72 R.GPTSTSIDNIDGTPVRDER.S sp|Q5VT52|RPRD2_HUMAN 1 2028.9712 1.82 116789 12802 3 2028.975484 677.331 Regulation of nuclear pre-mRNA domain-containing protein 2 OS=Homo sapiens OX=9606 GN=RPRD2 PE=1 SV=1 4.23 2384.5 - 592631 - - - 2.0986 - 2.944 0.432 - 239.3 1 2 1 0.0043 19 0 0 0 3.18E+07 1.75E+07 - - - 6.008 1 221125_WJC_METTL3_EV_vs_WT_F08.12804.12804.4 3.66E-07 19/102 R.AVHEQLAALSQGPISK[136.11]PK[136.11].R "sp|P25440|BRD2_HUMAN,tr|H0Y6K2|H0Y6K2_HUMAN,tr|U3KQA6|U3KQA6_HUMAN,tr|A0A0G2JHL0|A0A0G2JHL0_HUMAN,tr|A0A140T9F7|A0A140T9F7_HUMAN,tr|A0A0G2JK44|A0A0G2JK44_HUMAN,tr|A0A140T9E9|A0A140T9E9_HUMAN,tr|A0A0G2JHN8|A0A0G2JHN8_HUMAN,tr|A0A140T9I1|A0A140T9I1_HUMAN,tr|A0A140T9V2|A0A140T9V2_HUMAN" 10 1889.0705 0.98 116791 12804 4 1889.073304 473.2749 Bromodomain-containing protein 2 OS=Homo sapiens OX=9606 GN=BRD2 PE=1 SV=2 8.64 2384.8 - 469055 - - - 1.4594 - 2.654 0.544 - 261.8 1 2 0 0.0028 18 0 0 0 7.50E+06 7.64E+06 - - - 4.2946 0.9993 221125_WJC_METTL3_EV_vs_WT_F08.12807.12807.3 0.00226 Dec-72 R.QQTLSEYQDTGNTGDSSLK[136.11].G tr|A0A1B0GTZ1|A0A1B0GTZ1_HUMAN 1 2078.9484 2.28 116794 12807 3 2078.951139 693.9901 Synaptotagmin-14 OS=Homo sapiens OX=9606 GN=SYT14 PE=4 SV=1 4.03 2385.1 - 147219 - - - 1.331 - 1.925 0.323 - 114 1 2 0 0.0028 19 0 0 0 2.12E+06 9.27E+05 - - - 3.7494 0.9997 221125_WJC_METTL3_EV_vs_WT_F08.12810.12810.3 0.0187 13/72 R.GPTSTSIDNIDGTPVR[166.11]DER[166.11].S sp|Q5VT52|RPRD2_HUMAN 1 2048.9878 1.83 116795 12810 3 2048.986401 684.0032 Regulation of nuclear pre-mRNA domain-containing protein 2 OS=Homo sapiens OX=9606 GN=RPRD2 PE=1 SV=1 4.23 2385.5 - 722516 - - - -0.6662 - 2.424 0.429 - 177.4 1 2 1 -0.0014 19 0 0 0 3.19E+07 1.75E+07 - - - 5.4978 1 221125_WJC_METTL3_EV_vs_WT_F08.12811.12811.3 6.22E-10 19/68 R.AVHEQLAALSQGPISK[136.11]PK[136.11].R "sp|P25440|BRD2_HUMAN,tr|H0Y6K2|H0Y6K2_HUMAN,tr|U3KQA6|U3KQA6_HUMAN,tr|A0A0G2JHL0|A0A0G2JHL0_HUMAN,tr|A0A140T9F7|A0A140T9F7_HUMAN,tr|A0A0G2JK44|A0A0G2JK44_HUMAN,tr|A0A140T9E9|A0A140T9E9_HUMAN,tr|A0A0G2JHN8|A0A0G2JHN8_HUMAN,tr|A0A140T9I1|A0A140T9I1_HUMAN,tr|A0A140T9V2|A0A140T9V2_HUMAN" 10 1889.0705 0.63 116796 12811 3 1889.069137 630.6975 Bromodomain-containing protein 2 OS=Homo sapiens OX=9606 GN=BRD2 PE=1 SV=2 8.64 2385.7 - 404256 - - - -0.7464 - 3.165 0.58 - 482.3 1 2 0 -0.0014 18 0 0 0 5.01E+06 7.94E+06 - - - 7.875 0.9999 221125_WJC_METTL3_EV_vs_WT_F08.12814.12814.3 0.00703 Nov-64 K.VSDEPPQLPEPQPRPGR.L sp|O94761|RECQ4_HUMAN 1 1897.9646 1.61 116799 12814 3 1897.965893 633.6622 ATP-dependent DNA helicase Q4 OS=Homo sapiens OX=9606 GN=RECQL4 PE=1 SV=2 4.68 2386.1 - 231619 - - - 0.6681 - 1.98 0.447 - 140.1 1 2 0 0.0013 17 0 0 0 4.01E+06 2.49E+06 - - - 5.249 0.9999 221125_WJC_METTL3_EV_vs_WT_F08.12822.12822.4 8.47E-08 17/90 K.ELEDAYWK[136.11]DDDK[136.11]HVMR[166.11].K "sp|Q96CT7|CC124_HUMAN,tr|M0R2F5|M0R2F5_HUMAN" 2 2074.9629 2.3 116805 12822 4 2074.963702 519.748 Coiled-coil domain-containing protein 124 OS=Homo sapiens OX=9606 GN=CCDC124 PE=1 SV=1 4.52 2387.1 - 331312 - - - 0.4058 - 2.996 0.553 - 189.8 1 2 2 0.0008 16 0 0 0 8.94E+06 3.89E+06 - - - 4.4256 0.9999 221125_WJC_METTL3_EV_vs_WT_F08.12843.12843.3 3.84E-06 14/52 R.DK[136.11]PLK[136.11]DVIIADC[160.03]GK[136.11].L "sp|P23284|PPIB_HUMAN,tr|A0A7P0Z497|A0A7P0Z497_HUMAN,tr|A0A7P0TB45|A0A7P0TB45_HUMAN" 3 1594.8815 0.39 116820 12843 3 1594.882365 532.6344 Peptidyl-prolyl cis-trans isomerase B OS=Homo sapiens OX=9606 GN=PPIB PE=1 SV=2 6.03 2389.6 - 429733 - - - 0.5555 - 2.511 0.515 - 169.8 1 2 1 0.0009 14 0 0 0 3.26E+07 8.28E+07 - - - 6.7282 0.9969 221125_WJC_METTL3_EV_vs_WT_F08.12849.12849.4 0.00125 Oct-78 R.GK[136.11]DQVVILHHMLSK[136.11].A "sp|Q9H0A0|NAT10_HUMAN,tr|E9PMU0|E9PMU0_HUMAN,tr|E9PJN6|E9PJN6_HUMAN" 3 1619.9152 0.78 116826 12849 4 1619.920768 405.9861 RNA cytidine acetyltransferase OS=Homo sapiens OX=9606 GN=NAT10 PE=1 SV=2 8.61 2390.3 - 145921 - - - 3.4175 - 2.214 0.383 - 79.3 1 2 1 0.0055 14 0 0 0 1.24E+06 1.59E+06 - - - 2.8474 0.9997 221125_WJC_METTL3_EV_vs_WT_F08.12856.12856.4 0.00204 20/96 K.KTGQPMINLYTDRETGK.L "sp|P35637|FUS_HUMAN,tr|H3BPE7|H3BPE7_HUMAN" 2 1950.9833 0.95 116831 12856 4 1950.988065 488.7531 RNA-binding protein FUS OS=Homo sapiens OX=9606 GN=FUS PE=1 SV=1 8.5 2391.1 - 748883 - - - 2.4367 - 3.604 0.476 - 337.1 1 2 1 0.0048 17 0 0 0 2.40E+07 2.52E+07 - - - 3.8129 0.9999 221125_WJC_METTL3_EV_vs_WT_F08.12859.12859.4 8.50E-05 14/90 K.TLPAHSDPVSAVHFNR.D sp|P61964|WDR5_HUMAN 1 1746.8802 1.55 116834 12859 4 1746.883293 437.7273 WD repeat-containing protein 5 OS=Homo sapiens OX=9606 GN=WDR5 PE=1 SV=1 6.61 2391.5 - 448111 - - - 1.7895 - 2.264 0.443 - 105.1 1 2 0 0.0031 16 0 0 0 2.42E+07 1.56E+07 - - - 3.3688 0.9998 221125_WJC_METTL3_EV_vs_WT_F08.12860.12860.4 9.49E-05 13/78 K.LKEENFFGPKEEVK.L sp|Q9NZI8|IF2B1_HUMAN 1 1692.8723 1.2 116835 12860 4 1692.874942 424.2253 Insulin-like growth factor 2 mRNA-binding protein 1 OS=Homo sapiens OX=9606 GN=IGF2BP1 PE=1 SV=2 4.95 2391.6 - 388346 - - - 1.5683 - 2.298 0.473 - 88.9 1 2 2 0.0027 14 0 0 0 6.93E+06 5.75E+06 - - - 3.6451 0.9997 221125_WJC_METTL3_EV_vs_WT_F08.12861.12861.3 0.0016 14/60 K.GGR[166.11]GDVGSADIQDLEK[136.11].W "sp|Q9Y5M8|SRPRB_HUMAN,tr|H7C4H2|H7C4H2_HUMAN" 2 1633.8026 1.15 116836 12861 3 1633.804733 545.6082 Signal recognition particle receptor subunit beta OS=Homo sapiens OX=9606 GN=SRPRB PE=1 SV=3 4.23 2391.8 - 384717 - - - 1.2762 - 2.915 0.397 - 257.1 1 2 1 0.0021 16 0 0 0 5.98E+06 5.22E+06 - - - 5.7107 0.9972 221125_WJC_METTL3_EV_vs_WT_F08.12864.12864.3 0.00106 Oct-52 K.LKEENFFGPKEEVK.L sp|Q9NZI8|IF2B1_HUMAN 1 1692.8723 1.88 116839 12864 3 1692.878621 565.298 Insulin-like growth factor 2 mRNA-binding protein 1 OS=Homo sapiens OX=9606 GN=IGF2BP1 PE=1 SV=2 4.95 2392.2 - 244540 - - - 3.7416 - 2.113 0.426 - 63.1 1 2 2 0.0063 14 0 0 0 6.25E+06 3.32E+06 - - - 5.2758 1 221125_WJC_METTL3_EV_vs_WT_F08.12866.12866.2 8.97E-10 13/32 R.DSENLASPSEYPENGER.F "sp|P52948|NUP98_HUMAN,tr|A0A3B3ITD8|A0A3B3ITD8_HUMAN" 2 1892.8024 2.84 116841 12866 2 1892.801693 947.4085 Nuclear pore complex protein Nup98-Nup96 OS=Homo sapiens OX=9606 GN=NUP98 PE=1 SV=4 3.91 2392.4 - 199714 - - - -0.3888 - 2.807 0.711 - 390.5 1 2 0 -0.0007 17 0 0 0 4.27E+06 1.50E+06 - - - 6.8297 0.9964 221125_WJC_METTL3_EV_vs_WT_F08.12867.12867.3 0.00171 Nov-60 K.KPLTSNC[160.03]TIQIATPGK.G "sp|Q15061|WDR43_HUMAN,tr|C9IZK7|C9IZK7_HUMAN" 2 1727.924 0.87 116842 12867 3 1727.932913 576.9819 WD repeat-containing protein 43 OS=Homo sapiens OX=9606 GN=WDR43 PE=1 SV=3 9.31 2392.6 - 159841 - - - 5.1547 - 2.123 0.369 - 142.1 1 2 0 0.0089 16 0 0 0 4.62E+06 5.34E+06 - - - 4.5832 0.9997 221125_WJC_METTL3_EV_vs_WT_F08.12870.12870.3 0.00335 15/72 K.LNSVAAAANGLGAEKDPGR.S sp|Q9H7S9|ZN703_HUMAN 1 1809.9333 3.12 116843 12870 3 1809.93669 604.3184 Zinc finger protein 703 OS=Homo sapiens OX=9606 GN=ZNF703 PE=1 SV=1 6.07 2393 - 1.62E+06 - - - 1.8597 - 3.124 0.434 - 143.8 1 2 1 0.0034 19 0 0 0 2.55E+07 8.18E+06 - - - 6.1763 1 221125_WJC_METTL3_EV_vs_WT_F08.12875.12875.3 8.04E-10 22/56 K.SGQK[136.11]PVLDVHAELDR[166.11].L "sp|Q9Y6G9|DC1L1_HUMAN,tr|E9PHI6|E9PHI6_HUMAN" 2 1680.8914 0.84 116848 12875 3 1680.897431 561.3044 Cytoplasmic dynein 1 light intermediate chain 1 OS=Homo sapiens OX=9606 GN=DYNC1LI1 PE=1 SV=3 5.36 2393.4 - 914802 - - - 3.5862 - 3.793 0.653 - 604 1 2 0 0.006 15 0 0 0 8.80E+06 1.04E+07 - - - 9.2973 0.9989 221125_WJC_METTL3_EV_vs_WT_F08.12878.12878.4 0.0458 Sep-90 R.DGTGHYLC[160.03]NAC[160.03]GLYHK.M "sp|P23771|GATA3_HUMAN,sp|P23769|GATA2_HUMAN,sp|P43694|GATA4_HUMAN,sp|Q9BWX5|GATA5_HUMAN,tr|E9PKS4|E9PKS4_HUMAN,tr|B3KUF4|B3KUF4_HUMAN,tr|A0A087WZ09|A0A087WZ09_HUMAN" 7 1864.7985 1.57 116851 12878 4 1864.80383 467.2069 Trans-acting T-cell-specific transcription factor GATA-3 OS=Homo sapiens OX=9606 GN=GATA3 PE=1 SV=1 6.9 2393.8 - 633910 - - - 2.8647 - 1.612 0.352 - 64.3 1 2 0 0.0053 16 0 0 0 5.88E+06 3.75E+06 - - - 2.4565 0.9999 221125_WJC_METTL3_EV_vs_WT_F08.12880.12880.3 6.89E-07 18/52 R.DKPLKDVIIADC[160.03]GK.L "sp|P23284|PPIB_HUMAN,tr|A0A7P0Z497|A0A7P0Z497_HUMAN,tr|A0A7P0TB45|A0A7P0TB45_HUMAN" 3 1570.8389 0.39 116853 12880 3 1570.840519 524.6202 Peptidyl-prolyl cis-trans isomerase B OS=Homo sapiens OX=9606 GN=PPIB PE=1 SV=2 6.03 2394.1 - 377620 - - - 1.044 - 3.04 0.514 - 314.3 1 2 1 0.0016 14 0 0 0 3.24E+07 8.26E+07 - - - 7.2249 0.9997 221125_WJC_METTL3_EV_vs_WT_F08.12881.12881.3 2.70E-05 Dec-52 K.SQSTAQNLTSDIQR.L sp|Q96LB3|IFT74_HUMAN 1 1547.754 3.03 116854 12881 3 1547.757621 516.9253 Intraflagellar transport protein 74 homolog OS=Homo sapiens OX=9606 GN=IFT74 PE=1 SV=1 5.55 2394.2 - 285924 - - - 2.3634 - 2.191 0.39 - 207 1 2 0 0.0037 14 0 0 0 9.52E+06 3.14E+06 - - - 4.9716 1 221125_WJC_METTL3_EV_vs_WT_F08.12884.12884.3 1.10E-10 20/60 K.KDVDAAYMNKVELQAK.A "sp|P48668|K2C6C_HUMAN,sp|P04259|K2C6B_HUMAN,sp|Q14CN4|K2C72_HUMAN,sp|P02538|K2C6A_HUMAN" 4 1821.9295 81.59 116855 12884 3 1821.93222 608.3171 "Keratin, type II cytoskeletal 6C OS=Homo sapiens OX=9606 GN=KRT6C PE=1 SV=3" 6.12 2394.6 - 1.69E+06 - - - 1.5012 - 4.08 0.641 - 503.3 1 2 1 0.0027 16 0 0 0 4.62E+07 5.66E+05 - - - 9.2936 0.9998 221125_WJC_METTL3_EV_vs_WT_F08.12886.12886.3 7.86E-11 23/64 K.K[136.11]TGQPMINLYTDR[166.11]ETGK[136.11].L "sp|P35637|FUS_HUMAN,tr|H3BPE7|H3BPE7_HUMAN" 2 1977.02 1.34 116857 12886 3 1977.024379 660.0139 RNA-binding protein FUS OS=Homo sapiens OX=9606 GN=FUS PE=1 SV=1 8.5 2394.8 - 667464 - - - 2.2246 - 4.13 0.419 - 579 1 2 1 0.0044 17 0 0 0 1.49E+07 1.11E+07 - - - 6.7932 0.9713 221125_WJC_METTL3_EV_vs_WT_F08.12890.12890.3 4.79E-05 Dec-68 Q.STTVTSHLNSTSVDPYDR[166.11].H sp|Q9BQ04|RBM4B_HUMAN 1 1988.9315 2.26 116861 12890 3 1988.923799 663.9844 RNA-binding protein 4B OS=Homo sapiens OX=9606 GN=RBM4B PE=1 SV=1 5.19 2395.4 - 465222 - - - -3.8634 - 2.748 0.458 - 99.9 1 1 0 -0.0077 18 0 0 0 7.68E+06 3.40E+06 - - - 6.1613 0.9998 221125_WJC_METTL3_EV_vs_WT_F08.12891.12891.4 0.000998 15/78 R.DK[136.11]PLK[136.11]DVIIADC[160.03]GK[136.11].L "sp|P23284|PPIB_HUMAN,tr|A0A7P0Z497|A0A7P0Z497_HUMAN,tr|A0A7P0TB45|A0A7P0TB45_HUMAN" 3 1594.8815 0.34 116862 12891 4 1594.881732 399.7276 Peptidyl-prolyl cis-trans isomerase B OS=Homo sapiens OX=9606 GN=PPIB PE=1 SV=2 6.03 2395.5 - 387974 - - - 0.1586 - 2.548 0.48 - 180.2 1 2 1 0.0003 14 0 0 0 7.01E+06 2.03E+07 - - - 3.7442 0.9998 221125_WJC_METTL3_EV_vs_WT_F08.12893.12893.2 6.89E-07 Sep-32 R.DSENLASPSEYPENGER[166.11].F "sp|P52948|NUP98_HUMAN,tr|A0A3B3ITD8|A0A3B3ITD8_HUMAN" 2 1902.8107 2.73 116864 12893 2 1902.813154 952.4126 Nuclear pore complex protein Nup98-Nup96 OS=Homo sapiens OX=9606 GN=NUP98 PE=1 SV=4 3.91 2395.7 - 108424 - - - 1.2902 - 2.053 0.484 - 125.5 1 2 0 0.0025 17 0 0 0 6.77E+06 2.48E+06 - - - 4.3835 0.9999 221125_WJC_METTL3_EV_vs_WT_F08.12896.12896.4 1.62E-10 20/96 K.K[136.11]TGQPMINLYTDR[166.11]ETGK[136.11].L "sp|P35637|FUS_HUMAN,tr|H3BPE7|H3BPE7_HUMAN" 2 1977.02 0.96 116865 12896 4 1977.019381 495.2623 RNA-binding protein FUS OS=Homo sapiens OX=9606 GN=FUS PE=1 SV=1 8.5 2396.1 - 1.40E+06 - - - -0.3035 - 3.919 0.612 - 405.2 1 2 1 -0.0006 17 0 0 0 2.41E+07 2.52E+07 - - - 5.0269 1 221125_WJC_METTL3_EV_vs_WT_F08.12897.12897.3 1.43E-08 18/60 K.TLPAHSDPVSAVHFNR.D sp|P61964|WDR5_HUMAN 1 1746.8802 1.75 116866 12897 3 1746.882964 583.3007 WD repeat-containing protein 5 OS=Homo sapiens OX=9606 GN=WDR5 PE=1 SV=1 6.61 2396.3 - 663274 - - - 1.6011 - 3.217 0.625 - 416.5 1 2 0 0.0028 16 0 0 0 1.07E+07 6.09E+06 - - - 8.5054 0.9986 221125_WJC_METTL3_EV_vs_WT_F08.12899.12899.4 1.86E-05 17/90 K.TLPAHSDPVSAVHFNR[166.11].D sp|P61964|WDR5_HUMAN 1 1756.8884 1.56 116868 12899 4 1756.89056 440.2294 WD repeat-containing protein 5 OS=Homo sapiens OX=9606 GN=WDR5 PE=1 SV=1 6.61 2396.4 - 1.25E+06 - - - 1.2084 - 2.732 0.268 - 153.2 1 2 0 0.0021 16 0 0 0 2.40E+07 1.54E+07 - - - 1.9121 0.9998 221125_WJC_METTL3_EV_vs_WT_F08.12902.12902.3 1.06E-05 Dec-60 K.SQESNVSIQK[136.11]ENLELK[136.11].E "sp|Q15643|TRIPB_HUMAN,tr|H0YJ97|H0YJ97_HUMAN" 2 1860.9764 1.22 116871 12902 3 1860.977779 621.3327 Thyroid receptor-interacting protein 11 OS=Homo sapiens OX=9606 GN=TRIP11 PE=1 SV=3 4.78 2396.7 - 543448 - - - 0.7561 - 2.65 0.457 - 162.9 1 2 1 0.0014 16 0 0 0 1.68E+07 1.37E+07 - - - 6.1353 0.9608 221125_WJC_METTL3_EV_vs_WT_F08.12903.12903.4 0.0906 15/102 K.YK[136.11]PAVNQIEC[160.03]HPYLTQEK[136.11].L "sp|P15121|ALDR_HUMAN,tr|E9PCX2|E9PCX2_HUMAN" 2 2233.1172 1.41 116872 12903 4 2233.122562 559.2866 Aldo-keto reductase family 1 member B1 OS=Homo sapiens OX=9606 GN=AKR1B1 PE=1 SV=3 6.75 2396.8 - 465040 - - - 2.3837 - 2.103 0.167 - 149.1 1 2 0 0.0053 18 0 0 0 8.63E+06 6.13E+06 - - - 0.9327 0.9999 221125_WJC_METTL3_EV_vs_WT_F08.12904.12904.3 0.000267 Dec-68 R.ETQSPPSLQHSMSAVPGR.H "sp|Q9BYP7|WNK3_HUMAN,tr|A0A087WYK2|A0A087WYK2_HUMAN" 2 1907.916 1.53 116873 12904 3 1907.921341 636.9793 Serine\threonine-protein kinase WNK3 OS=Homo sapiens OX=9606 GN=WNK3 PE=1 SV=3 6.85 2396.9 - 420676 - - - 2.8204 - 2.34 0.522 - 137.1 1 2 0 0.0054 18 0 0 0 3.53E+06 2.30E+06 - - - 6.4753 0.9984 221125_WJC_METTL3_EV_vs_WT_F08.12910.12910.3 6.32E-07 18/44 L.RQSVEADINGLR.R "sp|P13645|K1C10_HUMAN,sp|Q2M2I5|K1C24_HUMAN,sp|P13646|K1C13_HUMAN,tr|A0A1B0GVI3|A0A1B0GVI3_HUMAN,tr|K7EMD9|K7EMD9_HUMAN,tr|K7ERE3|K7ERE3_HUMAN" 6 1356.711 40.94 116877 12910 3 1356.712958 453.2443 "Keratin, type I cytoskeletal 10 OS=Homo sapiens OX=9606 GN=KRT10 PE=1 SV=6" 6.07 2397.6 - 1.62E+06 - - - 1.4609 - 3.386 0.552 - 716.9 1 1 0 0.002 12 0 0 0 2.40E+07 5.87E+05 - - - 8.0744 0.9997 221125_WJC_METTL3_EV_vs_WT_F08.12913.12913.3 4.72E-08 21/92 K.LTIHAENPDSQAVPSAAGAASGEK[136.11].K "sp|O75970|MPDZ_HUMAN,tr|B7ZB24|B7ZB24_HUMAN,tr|H0YGQ3|H0YGQ3_HUMAN,tr|F5H1U9|F5H1U9_HUMAN,tr|A0A075B6R8|A0A075B6R8_HUMAN" 5 2328.1437 3.14 116880 12913 3 2329.147345 777.0552 Multiple PDZ domain protein OS=Homo sapiens OX=9606 GN=MPDZ PE=1 SV=2 4.65 2397.9 - 326836 - - - 431.0846 - 3.938 0.603 - 316 1 2 0 1.0036 24 0 0 0 2.81E+07 8.94E+06 - - - 8.1684 0.9996 221125_WJC_METTL3_EV_vs_WT_F08.12923.12923.4 1.22E-05 14/78 R.DKPLKDVIIADC[160.03]GK.L "sp|P23284|PPIB_HUMAN,tr|A0A7P0Z497|A0A7P0Z497_HUMAN,tr|A0A7P0TB45|A0A7P0TB45_HUMAN" 3 1570.8389 0.35 116886 12923 4 1570.842545 393.717 Peptidyl-prolyl cis-trans isomerase B OS=Homo sapiens OX=9606 GN=PPIB PE=1 SV=2 6.03 2399.2 - 372640 - - - 2.3338 - 2.113 0.478 - 78.5 1 2 1 0.0037 14 0 0 0 7.01E+06 2.03E+07 - - - 3.6578 0.9834 221125_WJC_METTL3_EV_vs_WT_F08.12924.12924.3 2.24E-05 13/64 Y.ISTQQAPSEADLEQYKK.A "sp|Q8WVM8|SCFD1_HUMAN,tr|A0A7I2V4U2|A0A7I2V4U2_HUMAN,tr|A0A7I2V4B8|A0A7I2V4B8_HUMAN,tr|H0YIZ7|H0YIZ7_HUMAN,tr|A0A7I2V5Z4|A0A7I2V5Z4_HUMAN,tr|B7Z5N7|B7Z5N7_HUMAN,tr|A0A7I2V5I2|A0A7I2V5I2_HUMAN,tr|A0A7I2V590|A0A7I2V590_HUMAN,tr|A0A7I2V2U5|A0A7I2V2U5_HUMAN,tr|A0A7I2V448|A0A7I2V448_HUMAN,tr|A0A7I2V320|A0A7I2V320_HUMAN,tr|A0A7I2V3G4|A0A7I2V3G4_HUMAN,tr|A0A7I2V3B4|A0A7I2V3B4_HUMAN,tr|G3V2M8|G3V2M8_HUMAN,tr|A0A7I2V4R0|A0A7I2V4R0_HUMAN" 15 1934.9585 0.39 116887 12924 3 1934.96365 645.9935 Sec1 family domain-containing protein 1 OS=Homo sapiens OX=9606 GN=SCFD1 PE=1 SV=4 4.68 2399.4 - 311424 - - - 2.643 - 2.93 0.41 - 220.9 1 1 0 0.0051 17 0 0 0 5.12E+06 1.31E+07 - - - 5.8255 1 221125_WJC_METTL3_EV_vs_WT_F08.12927.12927.3 2.38E-06 Nov-96 R.LSSQPVVVESSHPYTDDTSTSGTVK.L "sp|O95714|HERC2_HUMAN,tr|A0A3B3IRP6|A0A3B3IRP6_HUMAN,tr|A0A0J9YVP0|A0A0J9YVP0_HUMAN" 3 2620.2504 0.78 116890 12927 3 2620.251168 874.4241 E3 ubiquitin-protein ligase HERC2 OS=Homo sapiens OX=9606 GN=HERC2 PE=1 SV=2 4.54 2399.8 - 240926 - - - 0.2851 - 2.159 0.514 - 88.1 1 2 0 0.0007 25 0 0 0 1.19E+06 1.51E+06 - - - 6.0411 0.9994 221125_WJC_METTL3_EV_vs_WT_F08.12932.12932.4 1.84E-07 16/102 K.NLLIQNKPGDDPNKIVDK.V "sp|P35658|NU214_HUMAN,tr|A0A494BZU9|A0A494BZU9_HUMAN,tr|A0A494C1F2|A0A494C1F2_HUMAN" 3 2020.0953 2.27 116893 12932 4 2020.102192 506.0311 Nuclear pore complex protein Nup214 OS=Homo sapiens OX=9606 GN=NUP214 PE=1 SV=2 6.04 2400.4 - 554222 - - - 3.4097 - 2.83 0.496 - 138.4 1 2 1 0.0069 18 0 0 0 2.66E+07 1.17E+07 - - - 3.8976 1 221125_WJC_METTL3_EV_vs_WT_F08.12933.12933.3 7.01E-10 26/92 K.LTIHAENPDSQAVPSAAGAASGEK.K "sp|O75970|MPDZ_HUMAN,tr|B7ZB24|B7ZB24_HUMAN,tr|H0YGQ3|H0YGQ3_HUMAN,tr|F5H1U9|F5H1U9_HUMAN,tr|A0A075B6R8|A0A075B6R8_HUMAN" 5 2320.1295 3.15 116894 12933 3 2320.131882 774.3838 Multiple PDZ domain protein OS=Homo sapiens OX=9606 GN=MPDZ PE=1 SV=2 4.65 2400.4 - 1.45E+06 - - - 1.0189 - 4.938 0.594 - 502.6 1 2 0 0.0024 24 0 0 0 2.82E+07 8.94E+06 - - - 8.871 0.9996 221125_WJC_METTL3_EV_vs_WT_F08.12934.12934.3 8.69E-05 14/68 K.NLLIQNKPGDDPNKIVDK.V "sp|P35658|NU214_HUMAN,tr|A0A494BZU9|A0A494BZU9_HUMAN,tr|A0A494C1F2|A0A494C1F2_HUMAN" 3 2020.0953 2.65 116895 12934 3 2020.09924 674.3724 Nuclear pore complex protein Nup214 OS=Homo sapiens OX=9606 GN=NUP214 PE=1 SV=2 6.04 2400.6 - 372115 - - - 1.9484 - 2.482 0.455 - 154.5 1 2 1 0.0039 18 0 0 0 1.46E+07 5.52E+06 - - - 5.8754 0.9035 221125_WJC_METTL3_EV_vs_WT_F08.12935.12935.4 0.588 12/102 K.NLLIQNK[136.11]PGDDPNK[136.11]IVDK[136.11].V "sp|P35658|NU214_HUMAN,tr|A0A494BZU9|A0A494BZU9_HUMAN,tr|A0A494C1F2|A0A494C1F2_HUMAN" 3 2044.1379 2.27 116896 12935 4 2044.140494 512.0418 Nuclear pore complex protein Nup214 OS=Homo sapiens OX=9606 GN=NUP214 PE=1 SV=2 6.04 2400.7 - 337216 - - - 1.267 - 2.208 0.155 - 86.7 1 2 1 0.0026 18 0 0 0 2.66E+07 1.17E+07 - - - 0.8457 1 221125_WJC_METTL3_EV_vs_WT_F08.12936.12936.3 3.04E-05 Sep-96 R.LSSQPVVVESSHPYTDDTSTSGTVK[136.11].L "sp|O95714|HERC2_HUMAN,tr|A0A3B3IRP6|A0A3B3IRP6_HUMAN,tr|A0A0J9YVP0|A0A0J9YVP0_HUMAN" 3 2628.2646 0.78 116897 12936 3 2628.268277 877.0955 E3 ubiquitin-protein ligase HERC2 OS=Homo sapiens OX=9606 GN=HERC2 PE=1 SV=2 4.54 2400.8 - 263087 - - - 1.391 - 2.04 0.558 - 52.1 1 2 0 0.0037 25 0 0 0 1.19E+06 1.51E+06 - - - 6.4004 1 221125_WJC_METTL3_EV_vs_WT_F08.12938.12938.3 5.68E-11 13/80 N.C[160.03]TILQVQDETHSETADQQEAK.W sp|Q9BTC0|DIDO1_HUMAN 1 2430.0969 0.68 116899 12938 3 2430.102473 811.0396 Death-inducer obliterator 1 OS=Homo sapiens OX=9606 GN=DIDO1 PE=1 SV=5 4.17 2401.1 - 162757 - - - 2.2946 - 3.042 0.709 - 149.2 1 1 0 0.0056 21 0 0 0 1.50E+06 2.22E+06 - - - 9.1103 1 221125_WJC_METTL3_EV_vs_WT_F08.12939.12939.2 1.05E-07 Oct-34 R.TTSSANNPNLMYQDEC[160.03]DR.R "sp|Q92841|DDX17_HUMAN,tr|A0A5H1ZRQ2|A0A5H1ZRQ2_HUMAN,tr|A0A1X7SBZ2|A0A1X7SBZ2_HUMAN" 3 2114.8633 1.33 116900 12939 2 2114.867954 1058.4389 Probable ATP-dependent RNA helicase DDX17 OS=Homo sapiens OX=9606 GN=DDX17 PE=1 SV=2 4.03 2401.2 - 138551 - - - 2.1855 - 2.266 0.674 - 223.4 1 2 0 0.0046 18 0 0 0 1.80E+06 1.35E+06 - - - 6.0288 0.9996 221125_WJC_METTL3_EV_vs_WT_F08.12942.12942.4 0.17 17/84 M.PDSWDKDVYPEPPRR.T "sp|O96000|NDUBA_HUMAN,tr|H3BPJ9|H3BPJ9_HUMAN,tr|H3BV16|H3BV16_HUMAN" 3 1855.8853 1.94 116901 12942 4 1855.888316 464.9786 NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 10 OS=Homo sapiens OX=9606 GN=NDUFB10 PE=1 SV=3 4.69 2401.6 - 1.17E+06 - - - 1.6186 - 2.794 0.432 - 176.4 1 2 1 0.003 15 0 0 0 2.39E+07 1.23E+07 - - - 3.3529 0.9998 221125_WJC_METTL3_EV_vs_WT_F08.12943.12943.3 4.72E-05 Nov-56 K.TESNQEVANPEHYIK.H "sp|P06730|IF4E_HUMAN,tr|H0Y8J7|H0Y8J7_HUMAN,tr|D6RBW1|D6RBW1_HUMAN,tr|D6RFJ3|D6RFJ3_HUMAN" 4 1757.822 1.39 116902 12943 3 1757.825384 586.948 Eukaryotic translation initiation factor 4E OS=Homo sapiens OX=9606 GN=EIF4E PE=1 SV=2 4.75 2401.7 - 965957 - - - 1.9006 - 2.379 0.375 - 126.6 1 2 0 0.0033 15 0 0 0 2.13E+07 1.53E+07 - - - 4.9814 0.9663 221125_WJC_METTL3_EV_vs_WT_F08.12947.12947.4 0.0931 11/138 R.AAGNPGSLAAPIDHK[136.11]PC[160.03]SAPLEPK[136.11].S sp|Q14676|MDC1_HUMAN 1 2413.2395 0.01 116906 12947 4 2413.245679 604.3171 Mediator of DNA damage checkpoint protein 1 OS=Homo sapiens OX=9606 GN=MDC1 PE=1 SV=3 6.78 2402.1 - 773064 - - - 2.5687 - 1.989 0.182 - 51.8 1 2 0 0.0062 24 0 0 0 1.94E+05 2.55E+07 - - - 1.0291 0.9944 221125_WJC_METTL3_EV_vs_WT_F08.12957.12957.3 0.000133 17/40 K.KREEILEEIAK.V "sp|A0AV96|RBM47_HUMAN,tr|D6RBS9|D6RBS9_HUMAN,tr|B7Z8Z7|B7Z8Z7_HUMAN,tr|D6REZ6|D6REZ6_HUMAN,tr|D6R9D6|D6R9D6_HUMAN" 5 1356.7613 0.87 116914 12957 3 1356.764023 453.261 RNA-binding protein 47 OS=Homo sapiens OX=9606 GN=RBM47 PE=1 SV=2 4.95 2403.4 - 2.09E+06 - - - 2.0217 - 3.191 0.163 - 696.9 1 2 1 0.0027 11 0 0 0 2.89E+07 3.34E+07 - - - 3.6528 0.9999 221125_WJC_METTL3_EV_vs_WT_F08.12960.12960.3 9.14E-05 Dec-56 K.TESNQEVANPEHYIK[136.11].H "sp|P06730|IF4E_HUMAN,tr|H0Y8J7|H0Y8J7_HUMAN,tr|D6RBW1|D6RBW1_HUMAN,tr|D6RFJ3|D6RFJ3_HUMAN" 4 1765.8362 1.39 116917 12960 3 1765.841198 589.6194 Eukaryotic translation initiation factor 4E OS=Homo sapiens OX=9606 GN=EIF4E PE=1 SV=2 4.75 2403.7 - 799818 - - - 2.806 - 2.469 0.482 - 151.8 1 2 0 0.005 15 0 0 0 2.13E+07 1.53E+07 - - - 6.2708 0.9998 221125_WJC_METTL3_EV_vs_WT_F08.12961.12961.3 1.68E-05 13/68 K.NLLIQNK[136.11]PGDDPNK[136.11]IVDK[136.11].V "sp|P35658|NU214_HUMAN,tr|A0A494BZU9|A0A494BZU9_HUMAN,tr|A0A494C1F2|A0A494C1F2_HUMAN" 3 2044.1379 2.65 116918 12961 3 2044.139533 682.3866 Nuclear pore complex protein Nup214 OS=Homo sapiens OX=9606 GN=NUP214 PE=1 SV=2 6.04 2403.8 - 571756 - - - 0.7969 - 2.729 0.479 - 146.3 1 2 1 0.0016 18 0 0 0 1.46E+07 5.52E+06 - - - 6.3798 1 221125_WJC_METTL3_EV_vs_WT_F08.12972.12972.3 6.29E-10 24/92 K.AEVPGATGGDSPHLQPAEPPGEPR.R "sp|Q9P2K5|MYEF2_HUMAN,tr|A0A0A0MR39|A0A0A0MR39_HUMAN,tr|A0A087WWC8|A0A087WWC8_HUMAN,tr|A0A0A0MQW0|A0A0A0MQW0_HUMAN" 4 2365.1299 1.56 116927 12972 3 2365.134443 789.3839 Myelin expression factor 2 OS=Homo sapiens OX=9606 GN=MYEF2 PE=1 SV=3 4.4 2405.1 - 470912 - - - 1.9411 - 3.728 0.556 - 507.3 1 2 0 0.0046 24 0 0 0 1.10E+08 7.02E+07 - - - 7.7938 1 221125_WJC_METTL3_EV_vs_WT_F08.12973.12973.3 1.30E-08 20/92 K.AEVPGATGGDSPHLQPAEPPGEPR[166.11].R "sp|Q9P2K5|MYEF2_HUMAN,tr|A0A0A0MR39|A0A0A0MR39_HUMAN,tr|A0A087WWC8|A0A087WWC8_HUMAN,tr|A0A0A0MQW0|A0A0A0MQW0_HUMAN" 4 2375.1381 1.57 116928 12973 3 2375.138898 792.72 Myelin expression factor 2 OS=Homo sapiens OX=9606 GN=MYEF2 PE=1 SV=3 4.4 2405.2 - 372092 - - - 0.3267 - 3.371 0.581 - 303 1 2 0 0.0008 24 0 0 0 1.10E+08 7.02E+07 - - - 7.8398 0.9974 221125_WJC_METTL3_EV_vs_WT_F08.12983.12983.3 6.43E-05 16/40 K.K[136.11]R[166.11]EEILEEIAK[136.11].V "sp|A0AV96|RBM47_HUMAN,tr|D6RBS9|D6RBS9_HUMAN,tr|B7Z8Z7|B7Z8Z7_HUMAN,tr|D6REZ6|D6REZ6_HUMAN,tr|D6R9D6|D6R9D6_HUMAN" 5 1382.7979 1.13 116936 12983 3 1382.800423 461.9399 RNA-binding protein 47 OS=Homo sapiens OX=9606 GN=RBM47 PE=1 SV=2 4.95 2406.4 - 2.65E+06 - - - 1.7884 - 3.132 0.212 - 559.5 1 2 1 0.0025 11 0 0 0 2.69E+07 2.39E+07 - - - 4.1462 0.9998 221125_WJC_METTL3_EV_vs_WT_F08.12984.12984.3 8.02E-08 17/48 K.RNQSFC[160.03]PTVNLDK.L "sp|P46776|RL27A_HUMAN,tr|E9PLL6|E9PLL6_HUMAN,tr|E9PJD9|E9PJD9_HUMAN" 3 1577.762 0.76 116937 12984 3 1577.767179 526.928 60S ribosomal protein L27a OS=Homo sapiens OX=9606 GN=RPL27A PE=1 SV=2 8.22 2406.5 - 1.10E+06 - - - 3.266 - 2.983 0.417 - 435.7 1 2 0 0.0052 13 0 0 0 9.91E+06 1.30E+07 - - - 6.151 0.9997 221125_WJC_METTL3_EV_vs_WT_F08.12985.12985.4 8.32E-06 13/78 K.C[160.03]KAEHDQLLLNYAK.K "sp|P20700|LMNB1_HUMAN,tr|A0A0D9SFY5|A0A0D9SFY5_HUMAN,tr|E9PBF6|E9PBF6_HUMAN,tr|A0A0D9SFE5|A0A0D9SFE5_HUMAN" 4 1701.8508 1.23 116938 12985 4 1701.852802 426.47 Lamin-B1 OS=Homo sapiens OX=9606 GN=LMNB1 PE=1 SV=2 6.74 2406.6 - 770536 - - - 1.1523 - 2.292 0.449 - 163.9 1 2 1 0.002 14 0 0 0 7.69E+06 6.25E+06 - - - 3.4354 1 221125_WJC_METTL3_EV_vs_WT_F08.12989.12989.3 1.33E-08 23/92 K.VTTVVATPGQGPDR[166.11]PQEVSYTDTK[136.11].V "sp|P49841|GSK3B_HUMAN,tr|A0A7I2V3D8|A0A7I2V3D8_HUMAN,tr|A0A7I2V3T3|A0A7I2V3T3_HUMAN,tr|A0A7I2YQK0|A0A7I2YQK0_HUMAN,tr|A0A7I2V441|A0A7I2V441_HUMAN,tr|A0A7I2V4F3|A0A7I2V4F3_HUMAN,tr|A0A7I2V2V4|A0A7I2V2V4_HUMAN,tr|A0A3B3ITW1|A0A3B3ITW1_HUMAN,tr|A0A7I2V5K9|A0A7I2V5K9_HUMAN" 9 2563.2885 0.32 116942 12989 3 2563.28876 855.4368 Glycogen synthase kinase-3 beta OS=Homo sapiens OX=9606 GN=GSK3B PE=1 SV=2 4.56 2407.1 - 553849 - - - 0.1088 - 3.775 0.606 - 476.7 1 2 0 0.0003 24 0 0 0 3.02E+06 9.52E+06 - - - 8.3816 0.9976 221125_WJC_METTL3_EV_vs_WT_F08.12990.12990.4 0.000195 10/102 R.DTLLALHQHGHSGPFESK.F sp|Q7Z5L9|I2BP2_HUMAN 1 1972.9755 1.69 116943 12990 4 1972.982664 494.2512 Interferon regulatory factor 2-binding protein 2 OS=Homo sapiens OX=9606 GN=IRF2BP2 PE=1 SV=2 6.26 2407.2 - 461750 - - - 3.6189 - 2.28 0.329 - 55.7 1 2 0 0.0071 18 0 0 0 2.05E+07 1.21E+07 - - - 2.37 0.9999 221125_WJC_METTL3_EV_vs_WT_F08.12996.12996.3 3.01E-06 14/92 K.VTTVVATPGQGPDRPQEVSYTDTK.V "sp|P49841|GSK3B_HUMAN,tr|A0A7I2V3D8|A0A7I2V3D8_HUMAN,tr|A0A7I2V3T3|A0A7I2V3T3_HUMAN,tr|A0A7I2YQK0|A0A7I2YQK0_HUMAN,tr|A0A7I2V441|A0A7I2V441_HUMAN,tr|A0A7I2V4F3|A0A7I2V4F3_HUMAN,tr|A0A7I2V2V4|A0A7I2V2V4_HUMAN,tr|A0A3B3ITW1|A0A3B3ITW1_HUMAN,tr|A0A7I2V5K9|A0A7I2V5K9_HUMAN" 9 2545.266 0.32 116949 12996 3 2545.275179 849.4293 Glycogen synthase kinase-3 beta OS=Homo sapiens OX=9606 GN=GSK3B PE=1 SV=2 4.56 2407.9 - 217556 - - - 3.602 - 2.625 0.548 - 181.2 1 2 0 0.0092 24 0 0 0 3.02E+06 9.52E+06 - - - 6.8886 1 221125_WJC_METTL3_EV_vs_WT_F08.13001.13001.3 7.71E-12 23/68 K.NQDEC[160.03]VIALHDC[160.03]NGDVNR.A "sp|Q14157|UBP2L_HUMAN,tr|Q5VU78|Q5VU78_HUMAN,tr|F8W726|F8W726_HUMAN,tr|Q5VU81|Q5VU81_HUMAN,tr|Q5VU79|Q5VU79_HUMAN,tr|Q5VU80|Q5VU80_HUMAN,tr|Q5VU77|Q5VU77_HUMAN" 7 2127.9062 2.18 116952 13001 3 2127.907496 710.3093 Ubiquitin-associated protein 2-like OS=Homo sapiens OX=9606 GN=UBAP2L PE=1 SV=2 4.22 2408.6 - 3.80E+06 - - - 0.609 - 4.081 0.738 - 1093.8 1 2 0 0.0013 18 0 0 0 3.62E+07 1.66E+07 - - - 10.2695 1 221125_WJC_METTL3_EV_vs_WT_F08.13002.13002.3 1.72E-09 21/52 K.C[160.03]KAEHDQLLLNYAK.K "sp|P20700|LMNB1_HUMAN,tr|A0A0D9SFY5|A0A0D9SFY5_HUMAN,tr|E9PBF6|E9PBF6_HUMAN,tr|A0A0D9SFE5|A0A0D9SFE5_HUMAN" 4 1701.8508 1.09 116953 13002 3 1701.858452 568.2909 Lamin-B1 OS=Homo sapiens OX=9606 GN=LMNB1 PE=1 SV=2 6.74 2408.6 - 1.82E+06 - - - 4.4722 - 3.994 0.641 - 865 1 2 1 0.0076 14 0 0 0 1.44E+07 1.33E+07 - - - 9.3645 1 221125_WJC_METTL3_EV_vs_WT_F08.13003.13003.3 1.53E-09 22/68 K.NQDEC[160.03]VIALHDC[160.03]NGDVNR[166.11].A "sp|Q14157|UBP2L_HUMAN,tr|Q5VU78|Q5VU78_HUMAN,tr|F8W726|F8W726_HUMAN,tr|Q5VU81|Q5VU81_HUMAN,tr|Q5VU79|Q5VU79_HUMAN,tr|Q5VU80|Q5VU80_HUMAN,tr|Q5VU77|Q5VU77_HUMAN" 7 2137.9145 2.18 116954 13003 3 2137.915922 713.6454 Ubiquitin-associated protein 2-like OS=Homo sapiens OX=9606 GN=UBAP2L PE=1 SV=2 4.22 2408.7 - 1.87E+06 - - - 0.6792 - 4.142 0.672 - 891.7 1 2 0 0.0015 18 0 0 0 3.62E+07 1.66E+07 - - - 9.5706 0.9999 221125_WJC_METTL3_EV_vs_WT_F08.13007.13007.3 1.75E-08 17/48 K.R[166.11]NQSFC[160.03]PTVNLDK[136.11].L "sp|P46776|RL27A_HUMAN,tr|E9PLL6|E9PLL6_HUMAN,tr|E9PJD9|E9PJD9_HUMAN" 3 1595.7845 0.77 116958 13007 3 1595.788516 532.9354 60S ribosomal protein L27a OS=Homo sapiens OX=9606 GN=RPL27A PE=1 SV=2 8.22 2409 - 1.01E+06 - - - 2.5191 - 2.591 0.474 - 394.8 1 2 0 0.004 13 0 0 0 9.98E+06 1.30E+07 - - - 6.4048 0.9997 221125_WJC_METTL3_EV_vs_WT_F08.13008.13008.4 6.79E-06 15/78 K.C[160.03]K[136.11]AEHDQLLLNYAK[136.11].K "sp|P20700|LMNB1_HUMAN,tr|A0A0D9SFY5|A0A0D9SFY5_HUMAN,tr|E9PBF6|E9PBF6_HUMAN,tr|A0A0D9SFE5|A0A0D9SFE5_HUMAN" 4 1717.8792 1.23 116959 13008 4 1717.881788 430.4771 Lamin-B1 OS=Homo sapiens OX=9606 GN=LMNB1 PE=1 SV=2 6.74 2409.1 - 1.01E+06 - - - 1.4826 - 2.596 0.459 - 225.6 1 2 1 0.0025 14 0 0 0 7.69E+06 6.25E+06 - - - 3.5676 1 221125_WJC_METTL3_EV_vs_WT_F08.13009.13009.3 4.73E-10 25/68 K.VQEQVHTLLSQDQAQAAR.L sp|Q07065|CKAP4_HUMAN 1 2021.029 1.37 116960 13009 3 2021.025224 674.6836 Cytoskeleton-associated protein 4 OS=Homo sapiens OX=9606 GN=CKAP4 PE=1 SV=2 5.32 2409.2 - 886282 - - - -1.8763 - 4.198 0.637 - 1062.1 1 2 0 -0.0038 18 0 0 0 1.13E+07 8.23E+06 - - - 9.2132 1 221125_WJC_METTL3_EV_vs_WT_F08.13011.13011.3 4.16E-10 23/68 K.VQEQVHTLLSQDQAQAAR[166.11].L sp|Q07065|CKAP4_HUMAN 1 2031.0373 1.37 116962 13011 3 2031.041501 678.0197 Cytoskeleton-associated protein 4 OS=Homo sapiens OX=9606 GN=CKAP4 PE=1 SV=2 5.32 2409.4 - 769705 - - - 2.0753 - 4.086 0.619 - 949.5 1 2 0 0.0042 18 0 0 0 1.13E+07 8.23E+06 - - - 8.9451 1 221125_WJC_METTL3_EV_vs_WT_F08.13014.13014.3 4.08E-11 15/60 R.R[166.11]TEQEEDEELLTESSK[136.11].A sp|O60264|SMCA5_HUMAN 1 1939.8977 1.14 116965 13014 3 1939.899186 647.6399 SWI\SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A member 5 OS=Homo sapiens OX=9606 GN=SMARCA5 PE=1 SV=1 4.06 2409.8 - 614376 - - - 0.7506 - 2.957 0.625 - 420.4 1 2 0 0.0015 16 0 0 0 1.25E+07 1.10E+07 - - - 8.2896 1 221125_WJC_METTL3_EV_vs_WT_F08.13015.13015.3 2.79E-12 20/104 R.NAGDLAPAGGAASASTDEAADAESGTR[166.11].N "sp|Q9NXV6|CARF_HUMAN,tr|D6RGD2|D6RGD2_HUMAN,tr|J3KNE1|J3KNE1_HUMAN" 3 2442.077 1.65 116966 13015 3 2442.080579 815.033 CDKN2A-interacting protein OS=Homo sapiens OX=9606 GN=CDKN2AIP PE=1 SV=3 3.77 2409.9 - 496627 - - - 1.45 - 3.747 0.749 - 419.5 1 2 0 0.0035 27 0 0 0 5.75E+06 3.48E+06 - - - 9.9287 0.9021 221125_WJC_METTL3_EV_vs_WT_F08.13022.13022.3 0.14 Sep-76 K.ALNK[136.11]GDANSEVTVYYQSGTR[166.11].S "sp|O43847|NRDC_HUMAN,tr|G3V1R5|G3V1R5_HUMAN,tr|H0Y5G9|H0Y5G9_HUMAN" 3 2190.0672 0.89 116972 13022 3 2190.073066 731.0297 Nardilysin OS=Homo sapiens OX=9606 GN=NRDC PE=1 SV=3 6.11 2410.8 - 393597 - - - 2.6807 - 1.311 0.249 - 60 1 2 1 0.0059 20 0 0 0 1.59E+06 1.79E+06 - - - 1.9714 0.9999 221125_WJC_METTL3_EV_vs_WT_F08.13025.13025.3 0.000508 22/88 R.LKAEPAAPPAAPSTPAPPPAVPK.E sp|P48634|PRC2A_HUMAN 1 2174.2099 1.44 116975 13025 3 2174.211253 725.7439 Protein PRRC2A OS=Homo sapiens OX=9606 GN=PRRC2A PE=1 SV=3 8.59 2411.1 - 454761 - - - 0.6039 - 3.263 0.542 - 406.9 1 2 1 0.0013 23 0 0 0 1.81E+08 1.26E+08 - - - 7.3568 0.9999 221125_WJC_METTL3_EV_vs_WT_F08.13029.13029.3 2.35E-10 21/88 R.LK[136.11]AEPAAPPAAPSTPAPPPAVPK[136.11].E sp|P48634|PRC2A_HUMAN 1 2190.2383 1.43 116977 13029 3 2190.236355 731.0867 Protein PRRC2A OS=Homo sapiens OX=9606 GN=PRRC2A PE=1 SV=3 8.59 2411.7 - 533285 - - - -0.9063 - 3.611 0.498 - 344.2 1 2 1 -0.002 23 0 0 0 1.81E+08 1.26E+08 - - - 7.1038 1 221125_WJC_METTL3_EV_vs_WT_F08.13031.13031.3 1.52E-06 13/64 R.KPEEEEEEELEETAQEK.K sp|O43818|U3IP2_HUMAN 1 2074.9066 4.07 116979 13031 3 2074.910963 692.6428 U3 small nucleolar RNA-interacting protein 2 OS=Homo sapiens OX=9606 GN=RRP9 PE=1 SV=1 3.92 2411.9 - 380836 - - - 2.0931 - 2.926 0.557 - 309.1 1 2 0 0.0043 17 0 0 0 3.59E+07 8.82E+06 - - - 7.4611 0.797 221125_WJC_METTL3_EV_vs_WT_F08.13034.13034.4 0.354 Nov-72 K.KEKEPEYTLLTER.G "sp|O95793|STAU1_HUMAN,tr|Q5JW30|Q5JW30_HUMAN" 2 1634.8516 1.31 116982 13034 4 1634.852659 409.7202 Double-stranded RNA-binding protein Staufen homolog 1 OS=Homo sapiens OX=9606 GN=STAU1 PE=1 SV=2 4.95 2412.3 - 260826 - - - 0.6771 - 1.717 0.13 - 103.9 1 2 1 0.0011 13 0 0 0 2.68E+07 2.05E+07 - - - 0.5576 0.9998 221125_WJC_METTL3_EV_vs_WT_F08.13039.13039.3 4.17E-06 14/48 K.KEKEPEYTLLTER.G "sp|O95793|STAU1_HUMAN,tr|Q5JW30|Q5JW30_HUMAN" 2 1634.8516 2.01 116985 13039 3 1634.855167 545.9578 Double-stranded RNA-binding protein Staufen homolog 1 OS=Homo sapiens OX=9606 GN=STAU1 PE=1 SV=2 4.95 2412.9 - 1.81E+06 - - - 2.2112 - 2.696 0.552 - 278.8 1 2 1 0.0036 13 0 0 0 1.33E+08 6.61E+07 - - - 7.3822 1 221125_WJC_METTL3_EV_vs_WT_F08.13041.13041.3 2.32E-07 17/76 R.DDIIENAPTTHTEEYSGEEK.T "sp|O14744|ANM5_HUMAN,tr|G3V580|G3V580_HUMAN,tr|G3V2X6|G3V2X6_HUMAN,tr|G3V5L5|G3V5L5_HUMAN,tr|H0YJX6|H0YJX6_HUMAN" 5 2276.9921 3.26 116987 13041 3 2276.995019 760.0046 Protein arginine N-methyltransferase 5 OS=Homo sapiens OX=9606 GN=PRMT5 PE=1 SV=4 4 2413.2 - 354695 - - - 1.2903 - 3.71 0.672 - 337.1 1 2 0 0.0029 20 0 0 0 1.06E+08 3.24E+07 - - - 9.2119 0.9999 221125_WJC_METTL3_EV_vs_WT_F08.13042.13042.4 4.35E-06 14/84 K.GFGFVSYEKHEDANK.A "sp|Q13310|PABP4_HUMAN,tr|A0A7I2V5W9|A0A7I2V5W9_HUMAN,tr|B1ANR0|B1ANR0_HUMAN,tr|A0A7I2V4L7|A0A7I2V4L7_HUMAN,tr|H0YCC8|H0YCC8_HUMAN,tr|A0A7I2V598|A0A7I2V598_HUMAN,tr|H0Y5F5|H0Y5F5_HUMAN" 7 1726.7951 1.36 116988 13042 4 1726.797656 432.7061 Polyadenylate-binding protein 4 OS=Homo sapiens OX=9606 GN=PABPC4 PE=1 SV=1 5.45 2413.3 - 281968 - - - 1.4802 - 2.407 0.513 - 86.3 1 2 1 0.0026 15 0 0 0 2.03E+07 1.49E+07 - - - 4.0047 1 221125_WJC_METTL3_EV_vs_WT_F08.13044.13044.3 4.18E-07 Dec-68 R.DTLLALHQHGHSGPFESK.F sp|Q7Z5L9|I2BP2_HUMAN 1 1972.9755 2.39 116990 13044 3 1972.973589 658.6658 Interferon regulatory factor 2-binding protein 2 OS=Homo sapiens OX=9606 GN=IRF2BP2 PE=1 SV=2 6.26 2413.6 - 250107 - - - -0.9808 - 2.833 0.524 - 188.5 1 2 0 -0.0019 18 0 0 0 1.20E+07 5.04E+06 - - - 6.9746 0.9999 221125_WJC_METTL3_EV_vs_WT_F08.13047.13047.3 1.66E-06 18/48 K.K[136.11]EK[136.11]EPEYTLLTER[166.11].G "sp|O95793|STAU1_HUMAN,tr|Q5JW30|Q5JW30_HUMAN" 2 1660.8882 2.01 116991 13047 3 1660.890993 554.6367 Double-stranded RNA-binding protein Staufen homolog 1 OS=Homo sapiens OX=9606 GN=STAU1 PE=1 SV=2 4.95 2414 - 1.69E+06 - - - 1.6684 - 3.022 0.522 - 545.5 1 2 1 0.0028 13 0 0 0 1.33E+08 6.61E+07 - - - 7.3575 0.9998 221125_WJC_METTL3_EV_vs_WT_F08.13050.13050.3 3.50E-07 15/56 K.GFGFVSYEK[136.11]HEDANK[136.11].A "sp|Q13310|PABP4_HUMAN,tr|A0A7I2V5W9|A0A7I2V5W9_HUMAN,tr|B1ANR0|B1ANR0_HUMAN,tr|A0A7I2V4L7|A0A7I2V4L7_HUMAN,tr|H0YCC8|H0YCC8_HUMAN,tr|A0A7I2V598|A0A7I2V598_HUMAN,tr|H0Y5F5|H0Y5F5_HUMAN" 7 1742.8235 1.23 116994 13050 3 1742.826767 581.9484 Polyadenylate-binding protein 4 OS=Homo sapiens OX=9606 GN=PABPC4 PE=1 SV=1 5.45 2414.4 - 483497 - - - 1.8745 - 2.679 0.521 - 195.3 1 2 1 0.0033 15 0 0 0 2.22E+07 1.80E+07 - - - 6.9191 1 221125_WJC_METTL3_EV_vs_WT_F08.13052.13052.3 1.91E-08 18/68 R.HYTGPGDQTVNPQNGFVR.N "sp|Q9UHI6|DDX20_HUMAN,tr|A0A7P0T9T8|A0A7P0T9T8_HUMAN" 2 1985.9344 1.05 116996 13052 3 1985.926931 662.9854 Probable ATP-dependent RNA helicase DDX20 OS=Homo sapiens OX=9606 GN=DDX20 PE=1 SV=2 6.74 2414.6 - 343693 - - - -3.7544 - 3.479 0.656 - 374.4 1 2 0 -0.0075 18 0 0 0 3.53E+07 3.36E+07 - - - 8.9562 0.9999 221125_WJC_METTL3_EV_vs_WT_F08.13058.13058.3 3.02E-06 15/56 K.GFGFVSYEKHEDANK.A "sp|Q13310|PABP4_HUMAN,tr|A0A7I2V5W9|A0A7I2V5W9_HUMAN,tr|B1ANR0|B1ANR0_HUMAN,tr|A0A7I2V4L7|A0A7I2V4L7_HUMAN,tr|H0YCC8|H0YCC8_HUMAN,tr|A0A7I2V598|A0A7I2V598_HUMAN,tr|H0Y5F5|H0Y5F5_HUMAN" 7 1726.7951 1.23 117000 13058 3 1726.796072 576.6056 Polyadenylate-binding protein 4 OS=Homo sapiens OX=9606 GN=PABPC4 PE=1 SV=1 5.45 2415.3 - 875186 - - - 0.5629 - 2.714 0.543 - 157.6 1 2 1 0.001 15 0 0 0 2.22E+07 1.80E+07 - - - 7.1989 0.9996 221125_WJC_METTL3_EV_vs_WT_F08.13059.13059.4 4.53E-05 13/84 K.GFGFVSYEK[136.11]HEDANK[136.11].A "sp|Q13310|PABP4_HUMAN,tr|A0A7I2V5W9|A0A7I2V5W9_HUMAN,tr|B1ANR0|B1ANR0_HUMAN,tr|A0A7I2V4L7|A0A7I2V4L7_HUMAN,tr|H0YCC8|H0YCC8_HUMAN,tr|A0A7I2V598|A0A7I2V598_HUMAN,tr|H0Y5F5|H0Y5F5_HUMAN" 7 1742.8235 1.36 117001 13059 4 1742.824734 436.7132 Polyadenylate-binding protein 4 OS=Homo sapiens OX=9606 GN=PABPC4 PE=1 SV=1 5.45 2415.4 - 759693 - - - 0.708 - 1.825 0.43 - 77.5 1 2 1 0.0012 15 0 0 0 2.03E+07 1.50E+07 - - - 3.1836 0.9998 221125_WJC_METTL3_EV_vs_WT_F08.13060.13060.3 0.000326 Nov-48 R.SIFQHIQSAQSQR.S "sp|Q9Y2W1|TR150_HUMAN,tr|A0A3B3ITZ9|A0A3B3ITZ9_HUMAN" 2 1528.7746 2.55 117002 13060 3 1528.777084 510.5988 Thyroid hormone receptor-associated protein 3 OS=Homo sapiens OX=9606 GN=THRAP3 PE=1 SV=2 9.49 2415.5 - 571090 - - - 1.5993 - 1.992 0.418 - 111.4 1 2 0 0.0024 13 0 0 0 6.94E+08 2.72E+08 - - - 5.0681 0.9997 221125_WJC_METTL3_EV_vs_WT_F08.13064.13064.3 0.00577 Oct-44 K.TGNLGNVVHIER[166.11].F "sp|Q6P5R6|RL22L_HUMAN,tr|H0Y8C2|H0Y8C2_HUMAN,tr|C9JYQ9|C9JYQ9_HUMAN" 3 1317.7029 1.03 117006 13064 3 1317.704545 440.2416 60S ribosomal protein L22-like 1 OS=Homo sapiens OX=9606 GN=RPL22L1 PE=1 SV=2 6.41 2416 - 174071 - - - 1.2727 - 1.864 0.369 - 125.3 1 2 0 0.0017 12 0 0 0 3.17E+06 3.09E+06 - - - 4.3796 1 221125_WJC_METTL3_EV_vs_WT_F08.13068.13068.3 3.64E-11 23/76 R.DDIIENAPTTHTEEYSGEEK[136.11].T "sp|O14744|ANM5_HUMAN,tr|G3V580|G3V580_HUMAN,tr|G3V2X6|G3V2X6_HUMAN,tr|G3V5L5|G3V5L5_HUMAN,tr|H0YJX6|H0YJX6_HUMAN" 5 2285.0063 3.26 117008 13068 3 2285.007748 762.676 Protein arginine N-methyltransferase 5 OS=Homo sapiens OX=9606 GN=PRMT5 PE=1 SV=4 4 2416.5 - 1.12E+06 - - - 0.642 - 4.041 0.676 - 716.8 1 2 0 0.0015 20 0 0 0 1.06E+08 3.24E+07 - - - 9.4642 1 221125_WJC_METTL3_EV_vs_WT_F08.13074.13074.3 5.37E-07 22/92 R.EEEGPAGEAAASQPQAPTSVPGAR.L sp|Q9NR33|DPOE4_HUMAN 1 2306.0775 2.51 117012 13074 3 2306.078952 769.6998 DNA polymerase epsilon subunit 4 OS=Homo sapiens OX=9606 GN=POLE4 PE=1 SV=2 4.09 2417.3 - 805318 - - - 0.6374 - 3.144 0.489 - 356.1 1 2 0 0.0015 24 0 0 0 2.17E+07 8.63E+06 - - - 6.652 0.9999 221125_WJC_METTL3_EV_vs_WT_F08.13076.13076.3 6.13E-06 19/92 R.EEEGPAGEAAASQPQAPTSVPGAR[166.11].L sp|Q9NR33|DPOE4_HUMAN 1 2316.0858 2.51 117014 13076 3 2316.094508 773.0359 DNA polymerase epsilon subunit 4 OS=Homo sapiens OX=9606 GN=POLE4 PE=1 SV=2 4.09 2417.5 - 564177 - - - 3.7805 - 3.02 0.611 - 249.2 1 2 0 0.0088 24 0 0 0 2.17E+07 8.63E+06 - - - 7.9167 1 221125_WJC_METTL3_EV_vs_WT_F08.13077.13077.3 7.93E-08 19/68 R.HYTGPGDQTVNPQNGFVR[166.11].N "sp|Q9UHI6|DDX20_HUMAN,tr|A0A7P0T9T8|A0A7P0T9T8_HUMAN" 2 1995.9427 1.09 117015 13077 3 1995.943818 666.3215 Probable ATP-dependent RNA helicase DDX20 OS=Homo sapiens OX=9606 GN=DDX20 PE=1 SV=2 6.74 2417.7 - 500526 - - - 0.5817 - 3.685 0.582 - 470.5 1 2 0 0.0012 18 0 0 0 3.66E+07 3.37E+07 - - - 8.2762 1 221125_WJC_METTL3_EV_vs_WT_F08.13078.13078.3 8.88E-09 15/44 K.K[136.11]AVLFC[160.03]LSEDK[136.11]K[136.11].N "sp|P23528|COF1_HUMAN,tr|E9PP50|E9PP50_HUMAN,tr|G3V1A4|G3V1A4_HUMAN,tr|E9PQB7|E9PQB7_HUMAN,tr|E9PK25|E9PK25_HUMAN,tr|E9PLJ3|E9PLJ3_HUMAN,tr|E9PS23|E9PS23_HUMAN" 7 1460.8123 2.15 117016 13078 3 1460.813006 487.9447 Cofilin-1 OS=Homo sapiens OX=9606 GN=CFL1 PE=1 SV=3 8.18 2417.8 - 362795 - - - 0.458 - 2.776 0.517 - 319.7 1 2 0 0.0007 12 0 0 0 8.60E+06 4.01E+06 - - - 7.1339 0.9995 221125_WJC_METTL3_EV_vs_WT_F08.13082.13082.4 0.00572 17/72 K.K[136.11]EK[136.11]EPEYTLLTER[166.11].G "sp|O95793|STAU1_HUMAN,tr|Q5JW30|Q5JW30_HUMAN" 2 1660.8882 1.24 117018 13082 4 1660.890105 416.2293 Double-stranded RNA-binding protein Staufen homolog 1 OS=Homo sapiens OX=9606 GN=STAU1 PE=1 SV=2 4.95 2418.3 - 721808 - - - 1.1337 - 2.47 0.398 - 214.9 1 2 1 0.0019 13 0 0 0 2.69E+07 2.18E+07 - - - 3.0249 1 221125_WJC_METTL3_EV_vs_WT_F08.13084.13084.4 4.82E-07 19/108 R.VTVAGGVHISGLHTESAPR[166.11].R "sp|P49327|FAS_HUMAN,tr|A0A0U1RQF0|A0A0U1RQF0_HUMAN" 2 1897.0045 1.61 117020 13084 4 1897.00569 475.2584 Fatty acid synthase OS=Homo sapiens OX=9606 GN=FASN PE=1 SV=3 6.89 2418.5 - 1.35E+06 - - - 0.612 - 3.732 0.528 - 218.9 1 2 0 0.0012 19 0 0 0 4.73E+07 2.94E+07 - - - 4.2669 0.9995 221125_WJC_METTL3_EV_vs_WT_F08.13087.13087.2 6.91E-05 May-36 R.SSLGQSASETEEDTVSVSK.K "sp|Q13435|SF3B2_HUMAN,tr|E9PPJ0|E9PPJ0_HUMAN,tr|H0YCG1|H0YCG1_HUMAN,tr|E9PJ04|E9PJ04_HUMAN" 4 1939.8858 1.3 117023 13087 2 1939.885852 970.9502 Splicing factor 3B subunit 2 OS=Homo sapiens OX=9606 GN=SF3B2 PE=1 SV=2 4 2418.9 - 99819.3 - - - 0.0139 - 1.267 0.448 - 57.2 1 2 0 0 19 0 0 0 1.64E+06 1.26E+06 - - - 2.9317 1 221125_WJC_METTL3_EV_vs_WT_F08.13090.13090.2 8.31E-09 17/24 R.SIFQHIQSAQSQR.S "sp|Q9Y2W1|TR150_HUMAN,tr|A0A3B3ITZ9|A0A3B3ITZ9_HUMAN" 2 1528.7746 2.76 117024 13090 2 1528.774812 765.3946 Thyroid hormone receptor-associated protein 3 OS=Homo sapiens OX=9606 GN=THRAP3 PE=1 SV=2 9.49 2419.3 - 1.63E+06 - - - 0.1132 - 2.985 0.604 - 1216.4 1 2 0 0.0002 13 0 0 0 9.50E+07 3.44E+07 - - - 6.3088 0.9999 221125_WJC_METTL3_EV_vs_WT_F08.13091.13091.4 0.00393 13/96 K.MDLSESSKPLQQHLTTK.G "sp|Q2KHR3|QSER1_HUMAN,tr|A0A3B3IRW6|A0A3B3IRW6_HUMAN" 2 1941.983 1.68 117025 13091 4 1941.983255 486.503 Glutamine and serine-rich protein 1 OS=Homo sapiens OX=9606 GN=QSER1 PE=1 SV=3 6.51 2419.5 - 526133 - - - 0.1432 - 1.908 0.418 - 81.8 1 2 0 0.0003 17 0 0 0 1.52E+07 9.02E+06 - - - 3.0885 1 221125_WJC_METTL3_EV_vs_WT_F08.13092.13092.2 1.32E-08 15/32 R.TDYNASVSVPDSSGPER.L "sp|P61978|HNRPK_HUMAN,tr|Q5T6W2|Q5T6W2_HUMAN" 2 1779.7911 1.39 117026 13092 2 1779.789731 890.9028 Heterogeneous nuclear ribonucleoprotein K OS=Homo sapiens OX=9606 GN=HNRNPK PE=1 SV=1 4.03 2419.6 - 451293 - - - -0.7894 - 2.949 0.72 - 490.3 1 2 0 -0.0014 17 0 0 0 7.27E+07 5.22E+07 - - - 7.0173 1 221125_WJC_METTL3_EV_vs_WT_F08.13094.13094.2 9.08E-11 17/32 R.TDYNASVSVPDSSGPER[166.11].L "sp|P61978|HNRPK_HUMAN,tr|Q5T6W2|Q5T6W2_HUMAN" 2 1789.7994 1.39 117028 13094 2 1789.799144 895.907 Heterogeneous nuclear ribonucleoprotein K OS=Homo sapiens OX=9606 GN=HNRNPK PE=1 SV=1 4.03 2419.9 - 433704 - - - -0.1464 - 3.101 0.612 - 681.7 1 2 0 -0.0003 17 0 0 0 7.27E+07 5.22E+07 - - - 6.3435 0.9966 221125_WJC_METTL3_EV_vs_WT_F08.13095.13095.3 0.0367 Nov-48 K.VKLEEQLKETVEK.Y sp|Q9HAV7|GRPE1_HUMAN 1 1571.877 1.05 117029 13095 3 1571.879651 524.9663 "GrpE protein homolog 1, mitochondrial OS=Homo sapiens OX=9606 GN=GRPEL1 PE=1 SV=2" 4.95 2420 - 421228 - - - 1.6623 - 2.178 0.289 - 86.2 1 2 2 0.0026 13 0 0 0 3.19E+07 3.03E+07 - - - 3.8718 1 221125_WJC_METTL3_EV_vs_WT_F08.13097.13097.3 1.31E-06 18/88 K.LPTSSKPPGAVPSNALTNPAPSK.L sp|Q7Z434|MAVS_HUMAN 1 2230.1957 1.16 117031 13097 3 2230.201917 744.4059 Mitochondrial antiviral-signaling protein OS=Homo sapiens OX=9606 GN=MAVS PE=1 SV=2 10 2420.2 - 304888 - - - 2.7666 - 3.909 0.546 - 275.2 1 2 0 0.0062 23 0 0 0 4.96E+06 4.26E+06 - - - 7.8238 1 221125_WJC_METTL3_EV_vs_WT_F08.13100.13100.2 1.16E-08 Dec-36 R.SSLGQSASETEEDTVSVSK[136.11].K "sp|Q13435|SF3B2_HUMAN,tr|E9PPJ0|E9PPJ0_HUMAN,tr|H0YCG1|H0YCG1_HUMAN,tr|E9PJ04|E9PJ04_HUMAN" 4 1947.9 1.3 117034 13100 2 1947.895692 974.9573 Splicing factor 3B subunit 2 OS=Homo sapiens OX=9606 GN=SF3B2 PE=1 SV=2 4 2420.6 - 178012 - - - -2.2244 - 2.618 0.658 - 370.8 1 2 0 -0.0043 19 0 0 0 1.64E+06 1.26E+06 - - - 6.2658 0.9931 221125_WJC_METTL3_EV_vs_WT_F08.13103.13103.3 2.34E-06 13/56 K.MEEFK[136.11]DQLPADEC[160.03]NK[136.11].L "sp|P38646|GRP75_HUMAN,tr|A0A7I2V2S7|A0A7I2V2S7_HUMAN,tr|A0A7I2V2G2|A0A7I2V2G2_HUMAN,tr|A0A7I2V3F7|A0A7I2V3F7_HUMAN,tr|A0A7I2YQB2|A0A7I2YQB2_HUMAN,tr|D6RCD7|D6RCD7_HUMAN" 6 1868.8256 0.46 117035 13103 3 1869.824754 623.9491 "Stress-70 protein, mitochondrial OS=Homo sapiens OX=9606 GN=HSPA9 PE=1 SV=2" 4.18 2421 - 2.18E+06 - - - 534.6695 - 2.541 0.544 - 266.3 1 2 1 0.9992 15 0 0 0 1.76E+07 3.82E+07 - - - 6.7617 0.9999 221125_WJC_METTL3_EV_vs_WT_F08.13106.13106.4 2.03E-08 15/96 R.YESLTDPSK[136.11]LDSGK[136.11]ELK[136.11].L "sp|Q58FF8|H90B2_HUMAN,sp|P08238|HS90B_HUMAN,sp|Q58FF7|H90B3_HUMAN" 3 1933.0106 0.87 117038 13106 4 1933.014969 484.2599 Putative heat shock protein HSP 90-beta 2 OS=Homo sapiens OX=9606 GN=HSP90AB2P PE=1 SV=2 4.78 2421.4 - 515568 - - - 2.2405 - 3.005 0.568 - 107.7 1 2 2 0.0043 17 0 0 0 9.98E+06 1.15E+07 - - - 4.5507 0.9999 221125_WJC_METTL3_EV_vs_WT_F08.13111.13111.3 1.95E-06 Dec-56 K.MEEFKDQLPADEC[160.03]NK.L "sp|P38646|GRP75_HUMAN,tr|A0A7I2V2S7|A0A7I2V2S7_HUMAN,tr|A0A7I2V2G2|A0A7I2V2G2_HUMAN,tr|A0A7I2V3F7|A0A7I2V3F7_HUMAN,tr|A0A7I2YQB2|A0A7I2YQB2_HUMAN,tr|D6RCD7|D6RCD7_HUMAN" 6 1852.7972 0.46 117041 13111 3 1852.79472 618.6063 "Stress-70 protein, mitochondrial OS=Homo sapiens OX=9606 GN=HSPA9 PE=1 SV=2" 4.18 2422.1 - 887264 - - - -1.3115 - 2.328 0.542 - 196.4 1 2 1 -0.0024 15 0 0 0 1.76E+07 3.82E+07 - - - 6.787 0.999 221125_WJC_METTL3_EV_vs_WT_F08.13113.13113.3 0.00837 Nov-64 R.TDYNASVSVPDSSGPER.L "sp|P61978|HNRPK_HUMAN,tr|Q5T6W2|Q5T6W2_HUMAN" 2 1779.7911 1.65 117043 13113 3 1779.791623 594.271 Heterogeneous nuclear ribonucleoprotein K OS=Homo sapiens OX=9606 GN=HNRNPK PE=1 SV=1 4.03 2422.3 - 582626 - - - 0.2736 - 1.706 0.305 - 114.2 1 2 0 0.0005 17 0 0 0 2.05E+07 1.24E+07 - - - 3.2897 0.9947 221125_WJC_METTL3_EV_vs_WT_F08.13114.13114.4 4.70E-05 17/132 R.LK[136.11]AEPAAPPAAPSTPAPPPAVPK[136.11].E sp|P48634|PRC2A_HUMAN 1 2190.2383 1.92 117044 13114 4 2190.239299 548.5669 Protein PRRC2A OS=Homo sapiens OX=9606 GN=PRRC2A PE=1 SV=3 8.59 2422.4 - 347442 - - - 0.4379 - 2.65 0.275 - 172.9 1 2 1 0.001 23 0 0 0 1.21E+07 6.32E+06 - - - 1.9351 1 221125_WJC_METTL3_EV_vs_WT_F08.13120.13120.3 2.65E-05 Dec-48 R.SIFQHIQSAQSQR[166.11].S "sp|Q9Y2W1|TR150_HUMAN,tr|A0A3B3ITZ9|A0A3B3ITZ9_HUMAN" 2 1538.7829 2.55 117048 13120 3 1538.78304 513.9349 Thyroid hormone receptor-associated protein 3 OS=Homo sapiens OX=9606 GN=THRAP3 PE=1 SV=2 9.49 2423.3 - 1.73E+07 - - - 0.0851 - 2.168 0.496 - 138.6 1 2 0 0.0001 13 0 0 0 6.94E+08 2.72E+08 - - - 6.1679 0.9999 221125_WJC_METTL3_EV_vs_WT_F08.13121.13121.2 0.00015 15/24 R.SIFQHIQSAQSQR[166.11].S "sp|Q9Y2W1|TR150_HUMAN,tr|A0A3B3ITZ9|A0A3B3ITZ9_HUMAN" 2 1538.7829 2.76 117049 13121 2 1538.783717 770.3987 Thyroid hormone receptor-associated protein 3 OS=Homo sapiens OX=9606 GN=THRAP3 PE=1 SV=2 9.49 2423.3 - 1.83E+06 - - - 0.5251 - 2.863 0.535 - 884.9 1 2 0 0.0008 13 0 0 0 9.50E+07 3.44E+07 - - - 5.6919 1 221125_WJC_METTL3_EV_vs_WT_F08.13124.13124.3 3.82E-07 18/88 K.GEGAGPPPPLPPAQPGAEGGGDR.G "sp|Q5T9A4|ATD3B_HUMAN,sp|Q9NVI7|ATD3A_HUMAN,tr|A0A5K1VW56|A0A5K1VW56_HUMAN" 3 2079.9974 1.98 117052 13124 3 2079.999237 694.3397 ATPase family AAA domain-containing protein 3B OS=Homo sapiens OX=9606 GN=ATAD3B PE=1 SV=1 4.14 2423.7 - 319117 - - - 0.8923 - 2.965 0.549 - 237.7 1 2 0 0.0019 23 0 0 0 7.35E+06 3.71E+06 - - - 7.21 0.9997 221125_WJC_METTL3_EV_vs_WT_F08.13127.13127.3 0.000812 15/48 K.VK[136.11]LEEQLK[136.11]ETVEK[136.11].Y sp|Q9HAV7|GRPE1_HUMAN 1 1595.9196 1.05 117053 13127 3 1595.918546 532.9805 "GrpE protein homolog 1, mitochondrial OS=Homo sapiens OX=9606 GN=GRPEL1 PE=1 SV=2" 4.95 2424.1 - 1.64E+06 - - - -0.6842 - 2.833 0.385 - 188.5 1 2 2 -0.0011 13 0 0 0 3.17E+07 3.01E+07 - - - 5.6554 0.957 221125_WJC_METTL3_EV_vs_WT_F08.13128.13128.4 2.61E-05 18/108 K.K[136.11]LGEMWNNTAADDK[136.11]QPYEK[136.11].K "sp|P09429|HMGB1_HUMAN,tr|Q5T7C4|Q5T7C4_HUMAN" 2 2261.0849 0.18 117054 13128 4 2261.091785 566.2785 High mobility group protein B1 OS=Homo sapiens OX=9606 GN=HMGB1 PE=1 SV=3 4.78 2424.2 - 1.75E+06 - - - 3.0525 - 3.081 0.224 - 191.4 1 2 1 0.0069 19 0 0 0 1.11E+07 6.28E+07 - - - 1.5544 1 221125_WJC_METTL3_EV_vs_WT_F08.13129.13129.3 1.93E-09 27/68 R.C[160.03]QAAEPQIITGSHDTTIR[166.11].L "sp|O43660|PLRG1_HUMAN,tr|H0YA24|H0YA24_HUMAN" 2 2006.9719 1.37 117055 13129 3 2006.978346 669.9979 Pleiotropic regulator 1 OS=Homo sapiens OX=9606 GN=PLRG1 PE=1 SV=1 5.32 2424.3 - 1.38E+06 - - - 3.2073 - 3.36 0.616 - 996.7 1 2 0 0.0064 18 0 0 0 3.33E+07 2.44E+07 - - - 8.4239 0.999 221125_WJC_METTL3_EV_vs_WT_F08.13136.13136.4 0.0145 13/138 R.FIESAHTELAK[136.11]DDAAPAPPVADAK[136.11].A "sp|Q92667|AKAP1_HUMAN,tr|I3L0W0|I3L0W0_HUMAN" 2 2479.2566 1.07 117060 13136 4 2479.257296 620.8214 "A-kinase anchor protein 1, mitochondrial OS=Homo sapiens OX=9606 GN=AKAP1 PE=1 SV=1" 4.43 2425.2 - 1.04E+06 - - - 0.2932 - 2.243 0.369 - 82.8 1 2 1 0.0007 24 0 0 0 2.00E+07 1.86E+07 - - - 2.6969 1 221125_WJC_METTL3_EV_vs_WT_F08.13137.13137.3 7.41E-11 22/92 R.RVENSIPAAGETQNVEVAAGPAGK.C "sp|Q15020|SART3_HUMAN,tr|A0A499FI31|A0A499FI31_HUMAN" 2 2364.2034 11.07 117061 13137 3 2364.210877 789.0751 Squamous cell carcinoma antigen recognized by T-cells 3 OS=Homo sapiens OX=9606 GN=SART3 PE=1 SV=1 4.79 2425.3 - 617692 - - - 3.1833 - 3.823 0.644 - 414 1 2 0 0.0075 24 0 0 0 1.15E+07 1.04E+06 - - - 8.8326 1 221125_WJC_METTL3_EV_vs_WT_F08.13139.13139.3 4.37E-09 17/68 K.K[136.11]SQVFSTAADGQTQVEIK[136.11].V "sp|P38646|GRP75_HUMAN,tr|A0A7I2V2S7|A0A7I2V2S7_HUMAN,tr|A0A7I2V2G2|A0A7I2V2G2_HUMAN,tr|A0A7I2YQB2|A0A7I2YQB2_HUMAN,tr|D6RCD7|D6RCD7_HUMAN" 5 1952.0186 0.34 117063 13139 3 1952.023236 651.6801 "Stress-70 protein, mitochondrial OS=Homo sapiens OX=9606 GN=HSPA9 PE=1 SV=2" 6.07 2425.6 - 368961 - - - 2.3898 - 3.607 0.594 - 508.3 1 2 0 0.0047 18 0 0 0 2.64E+07 7.67E+07 - - - 8.3557 1 221125_WJC_METTL3_EV_vs_WT_F08.13140.13140.3 9.09E-06 Dec-80 K.GSVVNVNPTNTR[166.11]PQSDTPEIR[166.11].K "sp|O95819|M4K4_HUMAN,tr|A0A0D9SEY1|A0A0D9SEY1_HUMAN,tr|C9J840|C9J840_HUMAN,tr|E7EX83|E7EX83_HUMAN,tr|E7EN19|E7EN19_HUMAN,tr|H7C360|H7C360_HUMAN,tr|A0A0D9SG62|A0A0D9SG62_HUMAN,tr|G3XAA2|G3XAA2_HUMAN,tr|E7ENQ1|E7ENQ1_HUMAN,tr|H7C0P6|H7C0P6_HUMAN,tr|G5E948|G5E948_HUMAN" 11 2300.1624 0.22 117064 13140 3 2300.162348 767.7281 Mitogen-activated protein kinase kinase kinase kinase 4 OS=Homo sapiens OX=9606 GN=MAP4K4 PE=1 SV=2 6.07 2425.7 - 275239 - - - -0.0126 - 2.659 0.49 - 173.6 1 2 0 0 21 0 0 0 5.20E+05 2.35E+06 - - - 6.3476 0.9999 221125_WJC_METTL3_EV_vs_WT_F08.13150.13150.3 0.000908 Dec-64 K.MDLSESSKPLQQHLTTK.G "sp|Q2KHR3|QSER1_HUMAN,tr|A0A3B3IRW6|A0A3B3IRW6_HUMAN" 2 1941.983 4.47 117070 13150 3 1941.984755 648.3349 Glutamine and serine-rich protein 1 OS=Homo sapiens OX=9606 GN=QSER1 PE=1 SV=3 6.51 2426.9 - 288754 - - - 0.9156 - 2.195 0.449 - 155.9 1 2 0 0.0018 17 0 0 0 8.33E+06 1.86E+06 - - - 5.5315 0.9998 221125_WJC_METTL3_EV_vs_WT_F08.13151.13151.3 0.0016 15/52 R.HGVDHQVISVTFEK.A "sp|Q15020|SART3_HUMAN,tr|A0A499FI31|A0A499FI31_HUMAN" 2 1594.8104 2.77 117071 13151 3 1594.811924 532.6107 Squamous cell carcinoma antigen recognized by T-cells 3 OS=Homo sapiens OX=9606 GN=SART3 PE=1 SV=1 5.99 2427 - 1.31E+06 - - - 0.9832 - 2.118 0.378 - 202.7 1 2 0 0.0016 14 0 0 0 3.37E+07 1.22E+07 - - - 4.7483 0.9999 221125_WJC_METTL3_EV_vs_WT_F08.13152.13152.4 3.76E-06 14/102 K.K[136.11]LSSWDQAETPGHTPSLR[166.11].W sp|O75533|SF3B1_HUMAN 1 2027.0191 1.2 117072 13152 4 2027.022488 507.7621 Splicing factor 3B subunit 1 OS=Homo sapiens OX=9606 GN=SF3B1 PE=1 SV=3 6.75 2427.1 - 415556 - - - 1.6601 - 3.014 0.403 - 173.9 1 2 0 0.0034 18 0 0 0 2.33E+07 1.95E+07 - - - 3.1107 0.9999 221125_WJC_METTL3_EV_vs_WT_F08.13160.13160.3 2.37E-07 19/52 R.HGVDHQVISVTFEK[136.11].A "sp|Q15020|SART3_HUMAN,tr|A0A499FI31|A0A499FI31_HUMAN" 2 1602.8246 2.75 117078 13160 3 1602.82627 535.2821 Squamous cell carcinoma antigen recognized by T-cells 3 OS=Homo sapiens OX=9606 GN=SART3 PE=1 SV=1 5.99 2428.2 - 363931 - - - 1.0694 - 3.26 0.386 - 566.4 1 2 0 0.0017 14 0 0 0 3.38E+07 1.23E+07 - - - 5.9835 0.9994 221125_WJC_METTL3_EV_vs_WT_F08.13163.13163.4 0.00178 16/102 K.KLSSWDQAETPGHTPSLR.W sp|O75533|SF3B1_HUMAN 1 2008.9967 1.19 117079 13163 4 2009.001593 503.2564 Splicing factor 3B subunit 1 OS=Homo sapiens OX=9606 GN=SF3B1 PE=1 SV=3 6.75 2428.6 - 750140 - - - 2.4589 - 2.815 0.351 - 243.6 1 2 0 0.0049 18 0 0 0 2.33E+07 1.96E+07 - - - 2.6343 0.9865 221125_WJC_METTL3_EV_vs_WT_F08.13165.13165.3 1.15E-05 Nov-48 R.C[160.03]R[166.11]DDSFFGETSHN.Y "sp|P43243|MATR3_HUMAN,tr|A8MXP9|A8MXP9_HUMAN,tr|D6R991|D6R991_HUMAN,tr|A0A0R4J2E8|A0A0R4J2E8_HUMAN,tr|H0Y8T4|H0Y8T4_HUMAN,tr|D6REM6|D6REM6_HUMAN" 6 1580.6189 1.27 117081 13165 3 1580.621633 527.8803 Matrin-3 OS=Homo sapiens OX=9606 GN=MATR3 PE=1 SV=2 4.54 2428.8 - 1.47E+06 - - - 1.7038 - 1.951 0.62 - 67.3 1 1 1 0.0027 13 0 0 0 3.82E+07 3.00E+07 - - - 7.2637 0.9953 221125_WJC_METTL3_EV_vs_WT_F08.13171.13171.3 3.38E-07 15/48 R.C[160.03]RDDSFFGETSHN.Y "sp|P43243|MATR3_HUMAN,tr|A8MXP9|A8MXP9_HUMAN,tr|D6R991|D6R991_HUMAN,tr|A0A0R4J2E8|A0A0R4J2E8_HUMAN,tr|H0Y8T4|H0Y8T4_HUMAN,tr|D6REM6|D6REM6_HUMAN" 6 1570.6107 1.26 117085 13171 3 1570.611923 524.5442 Matrin-3 OS=Homo sapiens OX=9606 GN=MATR3 PE=1 SV=2 4.54 2429.4 - 2.18E+06 - - - 0.7978 - 2.388 0.673 - 191.9 1 1 1 0.0013 13 0 0 0 3.82E+07 3.04E+07 - - - 8.403 1 221125_WJC_METTL3_EV_vs_WT_F08.13173.13173.3 1.24E-10 17/68 K.K[136.11]LSSWDQAETPGHTPSLR[166.11].W sp|O75533|SF3B1_HUMAN 1 2027.0191 1.34 117087 13173 3 2027.027079 676.6803 Splicing factor 3B subunit 1 OS=Homo sapiens OX=9606 GN=SF3B1 PE=1 SV=3 6.75 2429.7 - 463868 - - - 3.925 - 3.38 0.623 - 301.4 1 2 0 0.008 18 0 0 0 1.50E+07 1.13E+07 - - - 8.5163 0.9999 221125_WJC_METTL3_EV_vs_WT_F08.13176.13176.4 8.41E-05 13/78 R.HGVDHQVISVTFEK.A "sp|Q15020|SART3_HUMAN,tr|A0A499FI31|A0A499FI31_HUMAN" 2 1594.8104 2.32 117090 13176 4 1594.812997 399.7099 Squamous cell carcinoma antigen recognized by T-cells 3 OS=Homo sapiens OX=9606 GN=SART3 PE=1 SV=1 5.99 2430 - 257715 - - - 1.656 - 2.184 0.446 - 127.2 1 2 0 0.0026 14 0 0 0 4.06E+06 1.75E+06 - - - 3.3915 0.9999 221125_WJC_METTL3_EV_vs_WT_F08.13177.13177.3 0.000108 Oct-72 K.SENGLEFTSSGSANTETTK.V "sp|P21796|VDAC1_HUMAN,tr|C9JI87|C9JI87_HUMAN" 2 1958.8705 1.53 117091 13177 3 1958.873325 653.9641 Voltage-dependent anion-selective channel protein 1 OS=Homo sapiens OX=9606 GN=VDAC1 PE=1 SV=2 4.25 2430.1 - 447531 - - - 1.4376 - 2.344 0.503 - 117 1 2 0 0.0028 19 0 0 0 3.24E+07 2.12E+07 - - - 6.24 1 221125_WJC_METTL3_EV_vs_WT_F08.13178.13178.2 1.26E-14 17/36 K.SENGLEFTSSGSANTETTK[136.11].V "sp|P21796|VDAC1_HUMAN,tr|C9JI87|C9JI87_HUMAN" 2 1966.8847 1.48 117092 13178 2 1966.883695 984.4496 Voltage-dependent anion-selective channel protein 1 OS=Homo sapiens OX=9606 GN=VDAC1 PE=1 SV=2 4.25 2430.3 - 145831 - - - -0.5155 - 3.685 0.716 - 1113.2 1 2 0 -0.001 19 0 0 0 7.39E+07 5.00E+07 - - - 7.5357 1 221125_WJC_METTL3_EV_vs_WT_F08.13180.13180.3 5.95E-13 19/68 K.KSQVFSTAADGQTQVEIK.V "sp|P38646|GRP75_HUMAN,tr|A0A7I2V2S7|A0A7I2V2S7_HUMAN,tr|A0A7I2V2G2|A0A7I2V2G2_HUMAN,tr|A0A7I2YQB2|A0A7I2YQB2_HUMAN,tr|D6RCD7|D6RCD7_HUMAN" 5 1935.9902 0.35 117093 13180 3 1935.992627 646.3373 "Stress-70 protein, mitochondrial OS=Homo sapiens OX=9606 GN=HSPA9 PE=1 SV=2" 6.07 2430.5 - 1.85E+06 - - - 1.2686 - 3.955 0.641 - 702.2 1 2 0 0.0025 18 0 0 0 2.64E+07 7.53E+07 - - - 9.1097 1 221125_WJC_METTL3_EV_vs_WT_F08.13182.13182.3 3.82E-08 15/48 R.C[160.03]R[166.11]DDSFFGETSHN.Y "sp|P43243|MATR3_HUMAN,tr|A8MXP9|A8MXP9_HUMAN,tr|D6R991|D6R991_HUMAN,tr|A0A0R4J2E8|A0A0R4J2E8_HUMAN,tr|H0Y8T4|H0Y8T4_HUMAN,tr|D6REM6|D6REM6_HUMAN" 6 1580.6189 1.27 117094 13182 3 1580.621359 527.8803 Matrin-3 OS=Homo sapiens OX=9606 GN=MATR3 PE=1 SV=2 4.54 2430.7 - 1.69E+06 - - - 1.5304 - 2.625 0.675 - 130.2 1 1 1 0.0024 13 0 0 0 3.82E+07 3.00E+07 - - - 8.6815 1 221125_WJC_METTL3_EV_vs_WT_F08.13189.13189.2 8.36E-15 18/36 K.SENGLEFTSSGSANTETTK.V "sp|P21796|VDAC1_HUMAN,tr|C9JI87|C9JI87_HUMAN" 2 1958.8705 1.49 117101 13189 2 1958.870544 980.4425 Voltage-dependent anion-selective channel protein 1 OS=Homo sapiens OX=9606 GN=VDAC1 PE=1 SV=2 4.25 2431.5 - 468781 - - - 0.0179 - 4.202 0.746 - 1108.8 1 2 0 0 19 0 0 0 7.44E+07 5.00E+07 - - - 8.0803 1 221125_WJC_METTL3_EV_vs_WT_F08.13191.13191.2 9.90E-14 14/34 K.K[136.11]SQVFSTAADGQTQVEIK[136.11].V "sp|P38646|GRP75_HUMAN,tr|A0A7I2V2S7|A0A7I2V2S7_HUMAN,tr|A0A7I2V2G2|A0A7I2V2G2_HUMAN,tr|A0A7I2YQB2|A0A7I2YQB2_HUMAN,tr|D6RCD7|D6RCD7_HUMAN" 5 1952.0186 0.09 117103 13191 2 1952.019304 977.0166 "Stress-70 protein, mitochondrial OS=Homo sapiens OX=9606 GN=HSPA9 PE=1 SV=2" 6.07 2431.8 - 142613 - - - 0.3755 - 3.256 0.67 - 461.6 1 2 0 0.0007 18 0 0 0 1.79E+05 1.88E+06 - - - 6.8917 0.9992 221125_WJC_METTL3_EV_vs_WT_F08.13195.13195.3 0.000342 Sep-68 K.ANELPQPPVPEPANAGK[136.11]R[166.11].K "sp|P78347|GTF2I_HUMAN,tr|A0A494C1K3|A0A494C1K3_HUMAN" 2 1902.0078 1.59 117105 13195 3 1902.012212 635.0099 General transcription factor II-I OS=Homo sapiens OX=9606 GN=GTF2I PE=1 SV=2 6.19 2432.3 - 277328 - - - 2.3039 - 2.016 0.343 - 80.1 1 2 0 0.0044 18 0 0 0 1.08E+07 6.81E+06 - - - 4.1087 1 221125_WJC_METTL3_EV_vs_WT_F08.13197.13197.3 5.77E-09 14/80 R.QVTSSGVSHGGTVSLQDAVTR.R "sp|O94901|SUN1_HUMAN,tr|H7C019|H7C019_HUMAN,tr|C9K051|C9K051_HUMAN,tr|E9PHI4|E9PHI4_HUMAN,tr|C9JK55|C9JK55_HUMAN" 5 2085.0451 1.45 117107 13197 3 2085.048052 696.0223 SUN domain-containing protein 1 OS=Homo sapiens OX=9606 GN=SUN1 PE=1 SV=4 6.74 2432.5 - 422880 - - - 1.435 - 2.969 0.556 - 215.5 1 2 0 0.003 21 0 0 0 5.35E+06 3.70E+06 - - - 7.347 0.9781 221125_WJC_METTL3_EV_vs_WT_F08.13202.13202.2 0.0221 28-May R.AGDWQC[160.03]PNPGC[160.03]GNQN.F "sp|Q01844|EWS_HUMAN,tr|B0QYK0|B0QYK0_HUMAN,tr|A0A0D9SFL3|A0A0D9SFL3_HUMAN,tr|C9JGE3|C9JGE3_HUMAN" 4 1673.6311 - 117112 13202 2 1673.631266 837.8228 RNA-binding protein EWS OS=Homo sapiens OX=9606 GN=EWSR1 PE=1 SV=1 3.8 2433.2 - 84465.4 - - - 0.1064 - 1.181 0.526 - 56.2 1 1 0 0.0002 15 0 0 0 - - - - - 3.335 1 221125_WJC_METTL3_EV_vs_WT_F08.13206.13206.3 8.82E-10 17/72 K.SENGLEFTSSGSANTETTK[136.11].V "sp|P21796|VDAC1_HUMAN,tr|C9JI87|C9JI87_HUMAN" 2 1966.8847 1.53 117114 13206 3 1966.884234 656.6355 Voltage-dependent anion-selective channel protein 1 OS=Homo sapiens OX=9606 GN=VDAC1 PE=1 SV=2 4.25 2433.7 - 1.14E+06 - - - -0.2415 - 3.438 0.656 - 461.5 1 2 0 -0.0005 19 0 0 0 3.24E+07 2.12E+07 - - - 8.8875 1 221125_WJC_METTL3_EV_vs_WT_F08.13209.13209.3 3.33E-06 Nov-68 K.ANELPQPPVPEPANAGKR.K "sp|P78347|GTF2I_HUMAN,tr|A0A494C1K3|A0A494C1K3_HUMAN" 2 1883.9854 2.34 117117 13209 3 1883.983366 629.0024 General transcription factor II-I OS=Homo sapiens OX=9606 GN=GTF2I PE=1 SV=2 6.19 2434.1 - 324978 - - - -1.0584 - 2.315 0.51 - 100.9 1 2 0 -0.002 18 0 0 0 1.93E+07 8.26E+06 - - - 6.3157 1 221125_WJC_METTL3_EV_vs_WT_F08.13212.13212.3 1.51E-06 16/88 R.APPAPPKPEPGEAPGASQC[160.03]MPLK.L sp|P50548|ERF_HUMAN 1 2326.145 3.13 117120 13212 3 2326.144682 776.3889 ETS domain-containing transcription factor ERF OS=Homo sapiens OX=9606 GN=ERF PE=1 SV=2 6.18 2434.4 - 257089 - - - -0.1255 - 3.254 0.534 - 253 1 2 0 -0.0003 23 0 0 0 1.89E+07 6.03E+06 - - - 7.2614 0.9999 221125_WJC_METTL3_EV_vs_WT_F08.13213.13213.2 7.30E-06 28-Nov K.QASIQHIQNAIDTEK.S "sp|P24539|AT5F1_HUMAN,tr|Q5QNZ2|Q5QNZ2_HUMAN" 2 1694.8588 1.37 117121 13213 2 1694.859849 848.4367 "ATP synthase F(0) complex subunit B1, mitochondrial OS=Homo sapiens OX=9606 GN=ATP5PB PE=1 SV=2" 5.32 2434.6 - 161730 - - - 0.6408 - 2.38 0.481 - 441.3 1 2 0 0.0011 15 0 0 0 1.03E+07 7.47E+06 - - - 4.7251 0.9999 221125_WJC_METTL3_EV_vs_WT_F08.13217.13217.3 5.58E-05 13/56 K.QASIQHIQNAIDTEK.S "sp|P24539|AT5F1_HUMAN,tr|Q5QNZ2|Q5QNZ2_HUMAN" 2 1694.8588 1.3 117123 13217 3 1694.860976 565.9602 "ATP synthase F(0) complex subunit B1, mitochondrial OS=Homo sapiens OX=9606 GN=ATP5PB PE=1 SV=2" 5.32 2435 - 4.67E+06 - - - 1.3057 - 2.735 0.427 - 341.7 1 2 0 0.0022 15 0 0 0 1.34E+08 1.03E+08 - - - 5.9254 0.9999 221125_WJC_METTL3_EV_vs_WT_F08.13219.13219.4 1.09E-06 17/114 K.GGAAVDPDSGLEHSAHVLEK[136.11].G "sp|P09874|PARP1_HUMAN,tr|A0A7I2V3E1|A0A7I2V3E1_HUMAN" 2 1995.9741 1.25 117125 13219 4 1995.977435 500.0008 Poly [ADP-ribose] polymerase 1 OS=Homo sapiens OX=9606 GN=PARP1 PE=1 SV=4 4.72 2435.2 - 493021 - - - 1.6543 - 3.5 0.454 - 221.2 1 2 0 0.0033 20 0 0 0 7.81E+08 6.24E+08 - - - 3.5955 0.9993 221125_WJC_METTL3_EV_vs_WT_F08.13222.13222.4 0.000511 14/108 R.VKHEVSGETVVFQGGALGK.T "sp|Q5VYK3|ECM29_HUMAN,tr|J3KN16|J3KN16_HUMAN,tr|A0A804HJA4|A0A804HJA4_HUMAN" 3 1941.032 0.88 117128 13222 4 1941.034514 486.2653 Proteasome adapter and scaffold protein ECM29 OS=Homo sapiens OX=9606 GN=ECPAS PE=1 SV=2 6.73 2435.6 - 398402 - - - 1.3076 - 2.698 0.382 - 180.6 1 2 1 0.0025 19 0 0 0 2.67E+06 3.03E+06 - - - 2.886 0.9998 221125_WJC_METTL3_EV_vs_WT_F08.13223.13223.4 2.14E-06 17/108 R.VK[136.11]HEVSGETVVFQGGALGK[136.11].T "sp|Q5VYK3|ECM29_HUMAN,tr|J3KN16|J3KN16_HUMAN,tr|A0A804HJA4|A0A804HJA4_HUMAN" 3 1957.0604 0.88 117129 13223 4 1957.05979 490.2724 Proteasome adapter and scaffold protein ECM29 OS=Homo sapiens OX=9606 GN=ECPAS PE=1 SV=2 6.73 2435.7 - 395488 - - - -0.2994 - 2.961 0.461 - 239.1 1 2 1 -0.0006 19 0 0 0 2.67E+06 3.03E+06 - - - 3.6056 1 221125_WJC_METTL3_EV_vs_WT_F08.13225.13225.2 3.35E-07 16/28 K.QASIQHIQNAIDTEK[136.11].S "sp|P24539|AT5F1_HUMAN,tr|Q5QNZ2|Q5QNZ2_HUMAN" 2 1702.873 1.37 117131 13225 2 1702.873128 852.4438 "ATP synthase F(0) complex subunit B1, mitochondrial OS=Homo sapiens OX=9606 GN=ATP5PB PE=1 SV=2" 5.32 2436 - 314803 - - - 0.0969 - 3.014 0.572 - 903.2 1 2 0 0.0002 15 0 0 0 1.03E+07 7.47E+06 - - - 5.9782 0.9917 221125_WJC_METTL3_EV_vs_WT_F08.13236.13236.4 0.00508 13/84 K.NSFQPISSLRDDERR.E sp|P98175|RBM10_HUMAN 1 1818.8973 0.57 117140 13236 4 1818.897122 455.7316 RNA-binding protein 10 OS=Homo sapiens OX=9606 GN=RBM10 PE=1 SV=3 6.12 2437.3 - 579636 - - - -0.083 - 2.032 0.261 - 114 1 2 1 -0.0002 15 0 0 0 9.25E+06 1.61E+07 - - - 1.7514 0.9997 221125_WJC_METTL3_EV_vs_WT_F08.13237.13237.4 0.000202 15/96 R.DLK[136.11]PNGANILVTEENK[136.11]K[136.11].E "sp|Q7Z6Z7|HUWE1_HUMAN,tr|H0Y659|H0Y659_HUMAN" 2 1906.0586 0.59 117141 13237 4 1906.058551 477.5219 E3 ubiquitin-protein ligase HUWE1 OS=Homo sapiens OX=9606 GN=HUWE1 PE=1 SV=3 6.18 2437.4 - 536415 - - - -0.0215 - 2.565 0.355 - 170.8 1 2 0 0 17 0 0 0 4.81E+06 8.18E+06 - - - 2.643 1 221125_WJC_METTL3_EV_vs_WT_F08.13241.13241.3 3.21E-12 20/72 K.TEELNREVATNSELVQSGK.S "sp|Q04695|K1C17_HUMAN,sp|P02533|K1C14_HUMAN,tr|K7ESE1|K7ESE1_HUMAN,tr|F5GWP8|F5GWP8_HUMAN" 4 2103.0444 999 117145 13241 3 2103.050922 702.0221 "Keratin, type I cytoskeletal 17 OS=Homo sapiens OX=9606 GN=KRT17 PE=1 SV=2" 4.49 2437.9 - 380648 - - - 3.1055 - 4.3 0.621 - 518.3 1 2 1 0.0065 19 0 0 0 2.19E+08 0.00E+00 - - - 9.0453 1 221125_WJC_METTL3_EV_vs_WT_F08.13245.13245.4 1.64E-07 21/114 K.GGAAVDPDSGLEHSAHVLEK.G "sp|P09874|PARP1_HUMAN,tr|A0A7I2V3E1|A0A7I2V3E1_HUMAN" 2 1987.9599 1.25 117147 13245 4 1987.961863 497.9973 Poly [ADP-ribose] polymerase 1 OS=Homo sapiens OX=9606 GN=PARP1 PE=1 SV=4 4.72 2438.4 - 5.52E+06 - - - 0.9708 - 4.048 0.633 - 402.8 1 2 0 0.0019 20 0 0 0 7.81E+08 6.24E+08 - - - 5.2026 1 221125_WJC_METTL3_EV_vs_WT_F08.13247.13247.3 3.70E-10 20/80 K.AIEDEGGNPDEIEITSEGNKK.T "sp|Q15424|SAFB1_HUMAN,tr|K7ES42|K7ES42_HUMAN" 2 2244.0394 1.59 117149 13247 3 2244.041129 749.0204 Scaffold attachment factor B1 OS=Homo sapiens OX=9606 GN=SAFB PE=1 SV=4 4 2438.7 - 541101 - - - 0.7861 - 3.26 0.67 - 315.8 1 2 0 0.0018 21 0 0 0 2.16E+08 1.36E+08 - - - 8.8425 0.998 221125_WJC_METTL3_EV_vs_WT_F08.13249.13249.3 0.006 Nov-60 K.EKLPGELEPVQATQNK.T "sp|O75821|EIF3G_HUMAN,tr|K7ER90|K7ER90_HUMAN,tr|K7EL20|K7EL20_HUMAN,tr|K7EP16|K7EP16_HUMAN" 4 1779.9367 25.68 117151 13249 3 1779.939038 594.3195 Eukaryotic translation initiation factor 3 subunit G OS=Homo sapiens OX=9606 GN=EIF3G PE=1 SV=2 4.79 2438.9 - 469256 - - - 1.3253 - 2.091 0.333 - 93.3 1 2 1 0.0024 16 0 0 0 1.05E+07 4.09E+05 - - - 4.1447 0.9999 221125_WJC_METTL3_EV_vs_WT_F08.13253.13253.3 2.02E-05 13/56 K.QASIQHIQNAIDTEK[136.11].S "sp|P24539|AT5F1_HUMAN,tr|Q5QNZ2|Q5QNZ2_HUMAN" 2 1702.873 1.3 117154 13253 3 1702.872242 568.6316 "ATP synthase F(0) complex subunit B1, mitochondrial OS=Homo sapiens OX=9606 GN=ATP5PB PE=1 SV=2" 5.32 2439.4 - 8.44E+06 - - - -0.4234 - 2.713 0.376 - 289.4 1 2 0 -0.0007 15 0 0 0 1.34E+08 1.03E+08 - - - 5.3361 0.9987 221125_WJC_METTL3_EV_vs_WT_F08.13258.13258.4 0.0899 15/96 R.DLKPNGANILVTEENKK.E "sp|Q7Z6Z7|HUWE1_HUMAN,tr|H0Y659|H0Y659_HUMAN" 2 1882.016 0.59 117159 13258 4 1882.014509 471.5113 E3 ubiquitin-protein ligase HUWE1 OS=Homo sapiens OX=9606 GN=HUWE1 PE=1 SV=3 6.18 2439.9 - 375300 - - - -0.788 - 2.743 0.271 - 188.9 1 2 0 -0.0015 17 0 0 0 4.81E+06 8.18E+06 - - - 1.9347 0.9907 221125_WJC_METTL3_EV_vs_WT_F08.13260.13260.4 0.000179 15/96 R.K[136.11]VSQPIEGHAASFAQFK[136.11].M "sp|Q00610|CLH1_HUMAN,tr|A0A087WVQ6|A0A087WVQ6_HUMAN" 2 1859.9865 1.47 117161 13260 4 1860.989663 466.0039 Clathrin heavy chain 1 OS=Homo sapiens OX=9606 GN=CLTC PE=1 SV=5 8.6 2440.2 - 296087 - - - 539.348 - 2.606 0.361 - 163.3 1 2 0 1.0032 17 0 0 0 1.94E+07 1.32E+07 - - - 2.4228 0.887 221125_WJC_METTL3_EV_vs_WT_F08.13263.13263.4 0.00683 13/78 R.K[136.11]IELFGR[166.11]PHNVQPN.W sp|Q86U44|MTA70_HUMAN 1 1665.907 0.01 117163 13263 4 1665.906797 417.484 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 8.75 2440.5 - 498299 - - - -0.1183 - 2.09 0.291 - 177.1 1 1 0 -0.0002 14 0 0 0 2.36E+05 2.21E+07 - - - 2.0271 0.9985 221125_WJC_METTL3_EV_vs_WT_F08.13265.13265.3 1.66E-05 19/76 R.RLLEGEDAHLSSQQASGQSY.S sp|P08779|K1C16_HUMAN 1 2175.0192 185.06 117164 13265 3 2175.016491 726.0137 "Keratin, type I cytoskeletal 16 OS=Homo sapiens OX=9606 GN=KRT16 PE=1 SV=4" 4.65 2440.7 - 2.40E+06 - - - -1.2634 - 3.564 0.553 - 480.6 1 1 0 -0.0027 20 0 0 0 3.66E+07 1.98E+05 - - - 7.7878 0.9985 221125_WJC_METTL3_EV_vs_WT_F08.13266.13266.4 0.0139 9/108 R.ETAWGASHHSMSQPIMVQR[166.11].R "sp|Q8TB72|PUM2_HUMAN,tr|C9JW01|C9JW01_HUMAN" 2 2162.0025 1.39 117165 13266 4 2162.000012 541.5079 Pumilio homolog 2 OS=Homo sapiens OX=9606 GN=PUM2 PE=1 SV=2 7.02 2440.8 - 677989 - - - -1.1494 - 1.622 0.286 - 39.4 1 2 0 -0.0025 19 0 0 0 2.39E+07 1.72E+07 - - - 1.8783 1 221125_WJC_METTL3_EV_vs_WT_F08.13267.13267.3 2.88E-06 16/76 K.GGAAVDPDSGLEHSAHVLEK.G "sp|P09874|PARP1_HUMAN,tr|A0A7I2V3E1|A0A7I2V3E1_HUMAN" 2 1987.9599 1.19 117166 13267 3 1987.95815 663.6606 Poly [ADP-ribose] polymerase 1 OS=Homo sapiens OX=9606 GN=PARP1 PE=1 SV=4 4.72 2440.9 - 7.75E+06 - - - -0.8969 - 2.988 0.528 - 245.8 1 2 0 -0.0018 20 0 0 0 3.90E+08 3.28E+08 - - - 7.0817 0.9994 221125_WJC_METTL3_EV_vs_WT_F08.13268.13268.4 0.00141 11/108 R.ETAWGASHHSMSQPIMVQR[166.11].R "sp|Q8TB72|PUM2_HUMAN,tr|C9JW01|C9JW01_HUMAN" 2 2162.0025 1.39 117167 13268 4 2161.99859 541.5079 Pumilio homolog 2 OS=Homo sapiens OX=9606 GN=PUM2 PE=1 SV=2 7.02 2441 - 677989 - - - -1.8071 - 2.092 0.339 - 68.7 1 2 0 -0.0039 19 0 0 0 2.39E+07 1.72E+07 - - - 2.4253 0.8413 221125_WJC_METTL3_EV_vs_WT_F08.13270.13270.3 0.126 Jul-56 K.NSFQPISSLRDDERR.E sp|P98175|RBM10_HUMAN 1 1818.8973 1.29 117169 13270 3 1818.900703 607.3064 RNA-binding protein 10 OS=Homo sapiens OX=9606 GN=RBM10 PE=1 SV=3 6.12 2441.2 - 434857 - - - 1.8858 - 1.562 0.146 - 59.3 1 2 1 0.0034 15 0 0 0 5.18E+06 4.02E+06 - - - 1.3305 0.9996 221125_WJC_METTL3_EV_vs_WT_F08.13273.13273.4 6.30E-06 16/120 K.VPVPEDK[136.11]YTAQVDAEEK[136.11]EDVK[136.11].S sp|O75947|ATP5H_HUMAN 1 2412.2123 1.54 117170 13273 4 2412.208796 604.0603 "ATP synthase subunit d, mitochondrial OS=Homo sapiens OX=9606 GN=ATP5PD PE=1 SV=3" 4.2 2441.6 - 1.50E+06 - - - -1.4323 - 2.831 0.426 - 109.1 1 2 2 -0.0035 21 0 0 0 2.63E+08 1.70E+08 - - - 3.277 0.9999 221125_WJC_METTL3_EV_vs_WT_F08.13276.13276.3 1.69E-09 Dec-80 K.VPVPEDKYTAQVDAEEKEDVK.S sp|O75947|ATP5H_HUMAN 1 2388.1697 1.58 117173 13276 3 2388.167438 797.0638 "ATP synthase subunit d, mitochondrial OS=Homo sapiens OX=9606 GN=ATP5PD PE=1 SV=3" 4.2 2442 - 435835 - - - -0.9267 - 2.347 0.643 - 119 1 2 2 -0.0022 21 0 0 0 6.56E+07 4.16E+07 - - - 7.7536 1 221125_WJC_METTL3_EV_vs_WT_F08.13277.13277.2 3.82E-11 19/36 K.TEELNKEVASNSELVQSSR.S "sp|P08779|K1C16_HUMAN,tr|K7ENW6|K7ENW6_HUMAN" 2 2119.0393 999 117174 13277 2 2119.031721 1060.5269 "Keratin, type I cytoskeletal 16 OS=Homo sapiens OX=9606 GN=KRT16 PE=1 SV=4" 4.49 2442.1 - 195477 - - - -3.5795 - 3.52 0.584 - 932.2 1 2 1 -0.0076 19 0 0 0 3.37E+08 0.00E+00 - - - 6.446 1 221125_WJC_METTL3_EV_vs_WT_F08.13281.13281.3 1.92E-09 16/72 K.LREAEETQSTLQAEC[160.03]DQYR.S "sp|Q9P2E9|RRBP1_HUMAN,tr|A0A087WU26|A0A087WU26_HUMAN,tr|A0A087WVV2|A0A087WVV2_HUMAN,tr|F8W7S5|F8W7S5_HUMAN" 4 2326.0496 1.29 117176 13281 3 2326.049829 776.3571 Ribosome-binding protein 1 OS=Homo sapiens OX=9606 GN=RRBP1 PE=1 SV=5 4.25 2442.6 - 1.08E+06 - - - 0.1187 - 3.239 0.6 - 295.7 1 2 1 0.0003 19 0 0 0 2.73E+07 2.12E+07 - - - 8.1167 0.9999 221125_WJC_METTL3_EV_vs_WT_F08.13283.13283.4 8.48E-06 14/108 R.ETAWGASHHSMSQPIMVQR.R "sp|Q8TB72|PUM2_HUMAN,tr|C9JW01|C9JW01_HUMAN" 2 2151.9942 1.38 117178 13283 4 2151.991237 539.0058 Pumilio homolog 2 OS=Homo sapiens OX=9606 GN=PUM2 PE=1 SV=2 7.02 2442.8 - 1.34E+06 - - - -1.3894 - 2.566 0.466 - 124.7 1 2 0 -0.003 19 0 0 0 2.41E+07 1.74E+07 - - - 3.6 0.7904 221125_WJC_METTL3_EV_vs_WT_F08.13285.13285.3 0.0765 Oct-56 R.STSHK[136.11]PDEIYGMIER[166.11].L sp|Q86U44|MTA70_HUMAN 1 1779.8581 0.001 117180 13285 3 1779.847537 594.2933 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 5.42 2443 - 597262 - - - -5.9089 - 1.731 0.173 - 110.8 1 2 0 -0.0105 15 0 0 0 0.00E+00 8.21E+06 - - - 1.8976 1 221125_WJC_METTL3_EV_vs_WT_F08.13287.13287.3 1.11E-09 17/80 K.VPVPEDK[136.11]YTAQVDAEEK[136.11]EDVK[136.11].S sp|O75947|ATP5H_HUMAN 1 2412.2123 1.58 117182 13287 3 2412.211491 805.078 "ATP synthase subunit d, mitochondrial OS=Homo sapiens OX=9606 GN=ATP5PD PE=1 SV=3" 4.2 2443.3 - 441575 - - - -0.3151 - 2.957 0.647 - 244.6 1 2 2 -0.0008 21 0 0 0 6.56E+07 4.16E+07 - - - 8.3525 1 221125_WJC_METTL3_EV_vs_WT_F08.13288.13288.3 1.08E-08 26/128 L.IC[160.03]NVGAGGPAPAAGAAPAGGPAPSTAAAPAEEK.K sp|P05386|RLA1_HUMAN 1 2855.3872 4.35 117183 13288 3 2855.383495 952.803 60S acidic ribosomal protein P1 OS=Homo sapiens OX=9606 GN=RPLP1 PE=1 SV=1 4.53 2443.4 - 344782 - - - -1.2996 - 4.208 0.653 - 365.1 1 1 0 -0.0037 33 0 0 0 1.12E+07 2.58E+06 - - - 9.1253 1 221125_WJC_METTL3_EV_vs_WT_F08.13294.13294.3 2.04E-09 25/72 K.LR[166.11]EAEETQSTLQAEC[160.03]DQYR[166.11].S "sp|Q9P2E9|RRBP1_HUMAN,tr|A0A087WU26|A0A087WU26_HUMAN,tr|A0A087WVV2|A0A087WVV2_HUMAN,tr|F8W7S5|F8W7S5_HUMAN" 4 2346.0661 1.28 117187 13294 3 2346.063942 783.0293 Ribosome-binding protein 1 OS=Homo sapiens OX=9606 GN=RRBP1 PE=1 SV=5 4.25 2444.1 - 1.54E+06 - - - -0.9169 - 4.701 0.656 - 944.9 1 2 1 -0.0022 19 0 0 0 2.72E+07 2.12E+07 - - - 9.6557 1 221125_WJC_METTL3_EV_vs_WT_F08.13297.13297.3 1.92E-09 21/64 R.K[136.11]VSQPIEGHAASFAQFK[136.11].M "sp|Q00610|CLH1_HUMAN,tr|A0A087WVQ6|A0A087WVQ6_HUMAN" 2 1859.9865 0.95 117190 13297 3 1859.982658 621.0028 Clathrin heavy chain 1 OS=Homo sapiens OX=9606 GN=CLTC PE=1 SV=5 8.6 2444.4 - 788354 - - - -2.0565 - 4.132 0.615 - 362.8 1 2 0 -0.0038 17 0 0 0 1.57E+07 1.66E+07 - - - 8.9798 0.9491 221125_WJC_METTL3_EV_vs_WT_F08.13298.13298.3 1.53E-05 15/52 D.PDSGLEHSAHVLEK.G "sp|P09874|PARP1_HUMAN,tr|A0A7I2V3E1|A0A7I2V3E1_HUMAN" 2 1517.7474 0.91 117191 13298 3 1517.738742 506.9231 Poly [ADP-ribose] polymerase 1 OS=Homo sapiens OX=9606 GN=PARP1 PE=1 SV=4 5.28 2444.5 - 587122 - - - -5.7183 - 3.126 0.499 - 260.9 1 1 0 -0.0087 14 0 0 0 7.11E+06 7.80E+06 - - - 7.1299 0.9999 221125_WJC_METTL3_EV_vs_WT_F08.13301.13301.3 0.000758 16/48 R.NREEEWDPEYTPK.S "sp|Q9Y2W1|TR150_HUMAN,tr|A0A3B3ITZ9|A0A3B3ITZ9_HUMAN" 2 1691.7427 2.92 117192 13301 3 1691.739329 564.9215 Thyroid hormone receptor-associated protein 3 OS=Homo sapiens OX=9606 GN=THRAP3 PE=1 SV=2 4.25 2444.9 - 2.01E+06 - - - -2.0104 - 2.847 0.543 - 479.7 1 2 1 -0.0034 13 0 0 0 5.79E+08 1.98E+08 - - - 7.4297 0.9998 221125_WJC_METTL3_EV_vs_WT_F08.13303.13303.4 1.10E-07 20/108 K.TEELNKEVASNSELVQSSR.S "sp|P08779|K1C16_HUMAN,tr|K7ENW6|K7ENW6_HUMAN" 2 2119.0393 310.42 117194 13303 4 2119.037217 530.7671 "Keratin, type I cytoskeletal 16 OS=Homo sapiens OX=9606 GN=KRT16 PE=1 SV=4" 4.49 2445.1 - 2.22E+06 - - - -0.9858 - 3.015 0.45 - 255 1 2 1 -0.0021 19 0 0 0 1.07E+08 3.43E+05 - - - 3.5155 1 221125_WJC_METTL3_EV_vs_WT_F08.13304.13304.3 1.18E-07 19/56 K.KAEAGAGSATEFQFR.G "sp|Q9NQ39|RS10L_HUMAN,sp|P46783|RS10_HUMAN" 2 1568.7583 1.25 117195 13304 3 1568.756366 523.9267 Putative 40S ribosomal protein S10-like OS=Homo sapiens OX=9606 GN=RPS10P5 PE=5 SV=1 6.14 2445.2 - 1.98E+06 - - - -1.2456 - 3.2 0.509 - 578.3 1 2 0 -0.002 15 0 0 0 2.44E+08 1.95E+08 - - - 7.2494 1 221125_WJC_METTL3_EV_vs_WT_F08.13305.13305.2 1.57E-07 13/32 R.AQVQEFC[160.03]DYGTK[136.11]EEC[160.03]MK[136.11].A "sp|Q86U44|MTA70_HUMAN,tr|H0YFV6|H0YFV6_HUMAN" 2 2137.909 -1 117196 13305 2 2138.903303 1069.9618 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 4.41 2445.3 - 1.22E+06 - - - 465.0993 - 2.4 0.745 - 326 1 2 1 0.9943 17 0 0 0 0.00E+00 0.00E+00 - - - 6.3837 0.9999 221125_WJC_METTL3_EV_vs_WT_F08.13306.13306.3 2.67E-07 15/48 R.NR[166.11]EEEWDPEYTPK[136.11].S "sp|Q9Y2W1|TR150_HUMAN,tr|A0A3B3ITZ9|A0A3B3ITZ9_HUMAN" 2 1709.7652 2.92 117197 13306 3 1709.761756 570.929 Thyroid hormone receptor-associated protein 3 OS=Homo sapiens OX=9606 GN=THRAP3 PE=1 SV=2 4.25 2445.4 - 829374 - - - -2.0143 - 2.818 0.629 - 434.2 1 2 1 -0.0034 13 0 0 0 5.79E+08 1.98E+08 - - - 8.3607 1 221125_WJC_METTL3_EV_vs_WT_F08.13314.13314.2 7.46E-07 24-Nov R.NREEEWDPEYTPK.S "sp|Q9Y2W1|TR150_HUMAN,tr|A0A3B3ITZ9|A0A3B3ITZ9_HUMAN" 2 1691.7427 3.74 117201 13314 2 1691.738289 846.8786 Thyroid hormone receptor-associated protein 3 OS=Homo sapiens OX=9606 GN=THRAP3 PE=1 SV=2 4.25 2446.4 - 483572 - - - -2.6251 - 2.364 0.679 - 324.4 1 2 1 -0.0044 13 0 0 0 5.92E+07 1.59E+07 - - - 6.2628 0.9998 221125_WJC_METTL3_EV_vs_WT_F08.13315.13315.3 6.34E-06 14/52 K.HELLSLASSNHLGK[136.11].N "sp|O15372|EIF3H_HUMAN,tr|B3KS98|B3KS98_HUMAN,tr|A0A087WZK9|A0A087WZK9_HUMAN,tr|E5RJT0|E5RJT0_HUMAN" 4 1512.814 2.24 117202 13315 3 1512.808571 505.2786 Eukaryotic translation initiation factor 3 subunit H OS=Homo sapiens OX=9606 GN=EIF3H PE=1 SV=1 6.92 2446.5 - 489986 - - - -3.5827 - 2.328 0.526 - 194.1 1 2 0 -0.0054 14 0 0 0 1.70E+07 7.59E+06 - - - 6.6485 0.9998 221125_WJC_METTL3_EV_vs_WT_F08.13317.13317.3 4.06E-05 Oct-52 K.NAC[160.03]DHLSGFNVC[160.03]NR[166.11].Y sp|Q9Y3B4|SF3B6_HUMAN 1 1672.7074 1.22 117204 13317 3 1672.699644 558.5764 Splicing factor 3B subunit 6 OS=Homo sapiens OX=9606 GN=SF3B6 PE=1 SV=1 6.73 2446.6 - 4.58E+06 - - - -4.6236 - 2.201 0.577 - 111.1 1 2 0 -0.0077 14 0 0 0 8.25E+07 6.74E+07 - - - 7.0674 1 221125_WJC_METTL3_EV_vs_WT_F08.13326.13326.3 0.00134 16/76 K.GGAAVDPDSGLEHSAHVLEK[136.11].G "sp|P09874|PARP1_HUMAN,tr|A0A7I2V3E1|A0A7I2V3E1_HUMAN" 2 1995.9741 1.19 117208 13326 3 1995.970971 666.332 Poly [ADP-ribose] polymerase 1 OS=Homo sapiens OX=9606 GN=PARP1 PE=1 SV=4 4.72 2447.8 - 9.01E+06 - - - -1.5842 - 3.503 0.596 - 254.3 1 2 0 -0.0032 20 0 0 0 3.90E+08 3.26E+08 - - - 8.2252 1 221125_WJC_METTL3_EV_vs_WT_F08.13327.13327.3 1.71E-09 21/80 K.AIEDEGGNPDEIEITSEGNK[136.11]K[136.11].T "sp|Q15424|SAFB1_HUMAN,tr|K7ES42|K7ES42_HUMAN" 2 2260.0678 1.6 117209 13327 3 2260.06278 754.3632 Scaffold attachment factor B1 OS=Homo sapiens OX=9606 GN=SAFB PE=1 SV=4 4 2447.9 - 2.95E+06 - - - -2.2057 - 2.85 0.542 - 173.6 1 2 0 -0.005 21 0 0 0 2.16E+08 1.36E+08 - - - 7.0923 1 221125_WJC_METTL3_EV_vs_WT_F08.13328.13328.3 6.92E-10 22/60 R.NSNLVGAAHEELQQSR.L "sp|P02545|LMNA_HUMAN,tr|A0A6Q8PF80|A0A6Q8PF80_HUMAN,tr|A0A804HL68|A0A804HL68_HUMAN,tr|Q5TCI8|Q5TCI8_HUMAN,tr|A0A6Q8PFJ0|A0A6Q8PFJ0_HUMAN,tr|A0A6Q8PHQ9|A0A6Q8PHQ9_HUMAN,tr|Q3BDU5|Q3BDU5_HUMAN" 7 1751.8551 2.2 117210 13328 3 1751.853599 584.959 Prelamin-A\C OS=Homo sapiens OX=9606 GN=LMNA PE=1 SV=1 5.4 2448 - 1.64E+06 - - - -0.842 - 4.06 0.52 - 1108.1 1 2 0 -0.0015 16 0 0 0 1.38E+08 6.27E+07 - - - 7.9323 0.9469 221125_WJC_METTL3_EV_vs_WT_F08.13331.13331.3 8.06E-07 16/64 R.AQVQEFC[160.03]DYGTK[136.11]EEC[160.03]MK[136.11].A "sp|Q86U44|MTA70_HUMAN,tr|H0YFV6|H0YFV6_HUMAN" 2 2137.909 0.02 117211 13331 3 2138.899534 713.6436 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 4.41 2448.4 - 9.77E+06 - - - 463.3364 - 3.16 0.589 - 232.2 1 2 1 0.9906 17 0 0 0 4.69E+06 2.82E+08 - - - 7.7391 1 221125_WJC_METTL3_EV_vs_WT_F08.13341.13341.3 0.000307 15/52 K.HELLSLASSNHLGK.N "sp|O15372|EIF3H_HUMAN,tr|B3KS98|B3KS98_HUMAN,tr|A0A087WZK9|A0A087WZK9_HUMAN,tr|E5RJT0|E5RJT0_HUMAN" 4 1504.7998 2.24 117216 13341 3 1504.797622 502.6072 Eukaryotic translation initiation factor 3 subunit H OS=Homo sapiens OX=9606 GN=EIF3H PE=1 SV=1 6.92 2449.6 - 642761 - - - -1.4414 - 2.831 0.505 - 281 1 2 0 -0.0022 14 0 0 0 1.70E+07 7.59E+06 - - - 6.9352 1 221125_WJC_METTL3_EV_vs_WT_F08.13343.13343.3 2.38E-10 19/60 K.IR[166.11]YESLTDPSK[136.11]LDSGK[136.11].E "sp|Q58FF8|H90B2_HUMAN,sp|P08238|HS90B_HUMAN,sp|Q58FF7|H90B3_HUMAN,sp|P07900|HS90A_HUMAN,tr|G3V2J8|G3V2J8_HUMAN" 5 1833.9683 0.52 117217 13343 3 1833.966447 612.33 Putative heat shock protein HSP 90-beta 2 OS=Homo sapiens OX=9606 GN=HSP90AB2P PE=1 SV=2 6.12 2449.8 - 2.07E+06 - - - -0.9902 - 3.572 0.628 - 564.6 1 2 2 -0.0018 16 0 0 0 3.43E+07 6.59E+07 - - - 8.8077 1 221125_WJC_METTL3_EV_vs_WT_F08.13344.13344.3 5.08E-07 19/60 R.NSNLVGAAHEELQQSR[166.11].L "sp|P02545|LMNA_HUMAN,tr|A0A6Q8PF80|A0A6Q8PF80_HUMAN,tr|A0A804HL68|A0A804HL68_HUMAN,tr|Q5TCI8|Q5TCI8_HUMAN,tr|A0A6Q8PFJ0|A0A6Q8PFJ0_HUMAN,tr|A0A6Q8PHQ9|A0A6Q8PHQ9_HUMAN,tr|Q3BDU5|Q3BDU5_HUMAN" 7 1761.8633 2.2 117218 13344 3 1761.860142 588.2951 Prelamin-A\C OS=Homo sapiens OX=9606 GN=LMNA PE=1 SV=1 5.4 2449.9 - 2.20E+06 - - - -1.8174 - 3.391 0.566 - 727.6 1 2 0 -0.0032 16 0 0 0 1.38E+08 6.27E+07 - - - 7.9827 1 221125_WJC_METTL3_EV_vs_WT_F08.13346.13346.2 3.22E-09 15/28 K.K[136.11]AEAGAGSATEFQFR[166.11].G "sp|Q9NQ39|RS10L_HUMAN,sp|P46783|RS10_HUMAN" 2 1586.7808 1.08 117220 13346 2 1586.780355 794.3977 Putative 40S ribosomal protein S10-like OS=Homo sapiens OX=9606 GN=RPS10P5 PE=5 SV=1 6.14 2450.2 - 505123 - - - -0.2741 - 3.43 0.577 - 538.7 1 2 0 -0.0004 15 0 0 0 1.37E+07 1.26E+07 - - - 6.3329 1 221125_WJC_METTL3_EV_vs_WT_F08.13351.13351.3 1.50E-07 15/48 R.LLEGEDAHLTQYK.K "sp|Q04695|K1C17_HUMAN,tr|A0A3B3IS58|A0A3B3IS58_HUMAN,tr|F5GWP8|F5GWP8_HUMAN" 3 1515.7569 15.19 117223 13351 3 1515.758522 506.2596 "Keratin, type I cytoskeletal 17 OS=Homo sapiens OX=9606 GN=KRT17 PE=1 SV=2" 4.65 2450.8 - 677817 - - - 1.0549 - 2.782 0.446 - 268.5 1 2 0 0.0016 13 0 0 0 1.16E+07 7.63E+05 - - - 6.2861 0.9999 221125_WJC_METTL3_EV_vs_WT_F08.13352.13352.3 1.13E-09 13/76 R.GDQPAASGDSDDDEPPPLPR.L sp|O00264|PGRC1_HUMAN 1 2034.8767 0.74 117224 13352 3 2034.883741 679.2995 Membrane-associated progesterone receptor component 1 OS=Homo sapiens OX=9606 GN=PGRMC1 PE=1 SV=3 3.61 2450.9 - 579956 - - - 3.4813 - 2.279 0.686 - 177.7 1 2 0 0.0071 20 0 0 0 1.81E+07 2.45E+07 - - - 8.1847 1 221125_WJC_METTL3_EV_vs_WT_F08.13356.13356.3 1.79E-06 17/56 K.K[136.11]AEAGAGSATEFQFR[166.11].G "sp|Q9NQ39|RS10L_HUMAN,sp|P46783|RS10_HUMAN" 2 1586.7808 1.25 117226 13356 3 1586.778714 529.9342 Putative 40S ribosomal protein S10-like OS=Homo sapiens OX=9606 GN=RPS10P5 PE=5 SV=1 6.14 2451.3 - 6.82E+06 - - - -1.3083 - 2.831 0.464 - 464.4 1 2 0 -0.0021 15 0 0 0 2.44E+08 1.95E+08 - - - 6.428 0.9999 221125_WJC_METTL3_EV_vs_WT_F08.13358.13358.3 1.68E-07 13/60 K.HNMDIGTWDNK[136.11]GPVPK[136.11].A sp|Q9BYJ9|YTHD1_HUMAN 1 1823.896 1.08 117228 13358 3 1823.89423 608.9726 YTH domain-containing family protein 1 OS=Homo sapiens OX=9606 GN=YTHDF1 PE=1 SV=1 6.75 2451.6 - 874566 - - - -0.9447 - 2.68 0.508 - 151.7 1 2 1 -0.0017 16 0 0 0 2.76E+07 2.54E+07 - - - 6.7327 0.9997 221125_WJC_METTL3_EV_vs_WT_F08.13359.13359.4 0.000173 13/96 R.VHTGEK[136.11]PFPC[160.03]PFPGC[160.03]GK[136.11].L "sp|O60481|ZIC3_HUMAN,sp|Q8N9L1|ZIC4_HUMAN,sp|Q96T25|ZIC5_HUMAN,sp|O95409|ZIC2_HUMAN,sp|Q15915|ZIC1_HUMAN,tr|C9JD04|C9JD04_HUMAN" 6 1929.9201 6.13 117229 13359 4 1929.920852 483.4873 Zinc finger protein ZIC 3 OS=Homo sapiens OX=9606 GN=ZIC3 PE=1 SV=1 8.03 2451.7 - 789075 - - - 0.4104 - 2.111 0.351 - 101.5 1 2 0 0.0008 17 0 0 0 1.64E+08 2.67E+07 - - - 2.5403 0.9997 221125_WJC_METTL3_EV_vs_WT_F08.13362.13362.3 4.24E-06 17/64 R.VHTGEK[136.11]PFPC[160.03]PFPGC[160.03]GK[136.11].L "sp|O60481|ZIC3_HUMAN,sp|Q8N9L1|ZIC4_HUMAN,sp|Q96T25|ZIC5_HUMAN,sp|O95409|ZIC2_HUMAN,sp|Q15915|ZIC1_HUMAN,tr|C9JD04|C9JD04_HUMAN" 6 1929.9201 2.76 117230 13362 3 1929.912889 644.314 Zinc finger protein ZIC 3 OS=Homo sapiens OX=9606 GN=ZIC3 PE=1 SV=1 8.03 2452.1 - 795498 - - - -3.7157 - 2.398 0.457 - 261 1 2 0 -0.0072 17 0 0 0 6.03E+07 2.19E+07 - - - 5.8427 1 221125_WJC_METTL3_EV_vs_WT_F08.13363.13363.2 1.06E-07 24-Dec R.NR[166.11]EEEWDPEYTPK[136.11].S "sp|Q9Y2W1|TR150_HUMAN,tr|A0A3B3ITZ9|A0A3B3ITZ9_HUMAN" 2 1709.7652 3.74 117231 13363 2 1709.764222 855.8899 Thyroid hormone receptor-associated protein 3 OS=Homo sapiens OX=9606 GN=THRAP3 PE=1 SV=2 4.25 2452.2 - 708812 - - - -0.572 - 2.469 0.623 - 418 1 2 1 -0.001 13 0 0 0 5.92E+07 1.59E+07 - - - 5.9618 0.861 221125_WJC_METTL3_EV_vs_WT_F08.13365.13365.4 0.0564 Sep-96 K.ELFQTPIC[160.03]TDK[136.11]PTTHEK[136.11].T sp|P46013|KI67_HUMAN 1 2060.0219 1.42 117233 13365 4 2060.012084 516.0128 Proliferation marker protein Ki-67 OS=Homo sapiens OX=9606 GN=MKI67 PE=1 SV=2 5.45 2452.5 - 420535 - - - -4.7854 - 1.989 0.182 - 57.5 1 2 0 -0.0099 17 0 0 0 6.57E+06 4.62E+06 - - - 1.0461 0.9995 221125_WJC_METTL3_EV_vs_WT_F08.13379.13379.4 3.23E-05 16/84 K.IK[136.11]SDHPGISITDLSK[136.11].K "sp|Q08945|SSRP1_HUMAN,tr|A0A0U1RRK2|A0A0U1RRK2_HUMAN" 2 1625.8959 0.77 117243 13379 4 1625.897552 407.4813 FACT complex subunit SSRP1 OS=Homo sapiens OX=9606 GN=SSRP1 PE=1 SV=1 6.75 2454.4 - 395354 - - - 0.9939 - 2.549 0.401 - 154.8 1 2 1 0.0016 15 0 0 0 6.49E+06 8.41E+06 - - - 3.0507 0.9999 221125_WJC_METTL3_EV_vs_WT_F08.13380.13380.2 3.98E-05 22-Dec R.AQVQEFC[160.03]DYGTK[136.11].E "sp|Q86U44|MTA70_HUMAN,tr|H0YFV6|H0YFV6_HUMAN" 2 1452.6435 0.2 117244 13380 2 1452.642105 727.329 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 4.37 2454.4 - 2.57E+06 - - - -0.9466 - 2.613 0.518 - 462.4 1 2 0 -0.0014 12 0 0 0 3.86E+07 1.91E+08 - - - 5.3938 1 221125_WJC_METTL3_EV_vs_WT_F08.13383.13383.2 2.00E-09 13/30 R.NSNLVGAAHEELQQSR.L "sp|P02545|LMNA_HUMAN,tr|A0A6Q8PF80|A0A6Q8PF80_HUMAN,tr|A0A804HL68|A0A804HL68_HUMAN,tr|Q5TCI8|Q5TCI8_HUMAN,tr|A0A6Q8PFJ0|A0A6Q8PFJ0_HUMAN,tr|A0A6Q8PHQ9|A0A6Q8PHQ9_HUMAN,tr|Q3BDU5|Q3BDU5_HUMAN" 7 1751.8551 3.14 117247 13383 2 1751.856659 876.9348 Prelamin-A\C OS=Homo sapiens OX=9606 GN=LMNA PE=1 SV=1 5.4 2454.8 - 222087 - - - 0.9048 - 2.659 0.677 - 505.5 1 2 0 0.0016 16 0 0 0 5.59E+06 1.78E+06 - - - 6.4452 0.9994 221125_WJC_METTL3_EV_vs_WT_F08.13390.13390.3 4.32E-05 14/60 R.QISDGER[166.11]EELNLTANR[166.11].L sp|O95816|BAG2_HUMAN 1 1863.919 0.02 117252 13390 3 1863.917017 622.3136 BAG family molecular chaperone regulator 2 OS=Homo sapiens OX=9606 GN=BAG2 PE=1 SV=1 4.41 2455.7 - 563656 - - - -1.0414 - 2.397 0.379 - 274 1 2 1 -0.0019 16 0 0 0 1.36E+05 5.96E+06 - - - 5.0081 0.9991 221125_WJC_METTL3_EV_vs_WT_F08.13391.13391.4 0.0005 15/84 K.IKSDHPGISITDLSK.K "sp|Q08945|SSRP1_HUMAN,tr|A0A0U1RRK2|A0A0U1RRK2_HUMAN" 2 1609.8675 0.68 117253 13391 4 1609.865455 403.4742 FACT complex subunit SSRP1 OS=Homo sapiens OX=9606 GN=SSRP1 PE=1 SV=1 6.75 2455.8 - 517040 - - - -1.2927 - 2.381 0.371 - 150 1 2 1 -0.0021 15 0 0 0 7.10E+06 1.04E+07 - - - 2.765 1 221125_WJC_METTL3_EV_vs_WT_F08.13399.13399.4 5.11E-05 21/114 R.LSSFYHHEAGVTALSQDPQR.L sp|Q86XL3|ANKL2_HUMAN 1 2242.0767 1.57 117259 13399 4 2242.079367 561.5264 Ankyrin repeat and LEM domain-containing protein 2 OS=Homo sapiens OX=9606 GN=ANKLE2 PE=1 SV=4 5.99 2456.7 - 818534 - - - 1.1922 - 3.78 0.522 - 246.2 1 2 0 0.0027 20 0 0 0 1.41E+07 9.02E+06 - - - 4.2133 1 221125_WJC_METTL3_EV_vs_WT_F08.13403.13403.2 2.74E-16 14/38 R.GDQPAASGDSDDDEPPPLPR.L sp|O00264|PGRC1_HUMAN 1 2034.8767 3.85 117263 13403 2 2034.876363 1018.4456 Membrane-associated progesterone receptor component 1 OS=Homo sapiens OX=9606 GN=PGRMC1 PE=1 SV=3 3.61 2457.2 - 299041 - - - -0.1445 - 3.341 0.78 - 326.7 1 2 0 -0.0003 20 0 0 0 9.85E+06 2.56E+06 - - - 7.7677 0.9902 221125_WJC_METTL3_EV_vs_WT_F08.13409.13409.3 0.0218 Oct-36 R.RKPFYPALIR.Y "sp|O00746|NDKM_HUMAN,tr|Q4TT34|Q4TT34_HUMAN,tr|H0Y6J0|H0Y6J0_HUMAN,tr|F2Z2X0|F2Z2X0_HUMAN,tr|A2IDC9|A2IDC9_HUMAN" 5 1259.7503 1.87 117267 13409 3 1259.747962 420.924 "Nucleoside diphosphate kinase, mitochondrial OS=Homo sapiens OX=9606 GN=NME4 PE=1 SV=1" 11 2458.2 - 370686 - - - -1.8258 - 1.914 0.15 - 153.6 1 2 0 -0.0023 10 0 0 0 4.82E+07 2.58E+07 - - - 2.1077 1 221125_WJC_METTL3_EV_vs_WT_F08.13411.13411.3 8.93E-08 16/76 R.LSSFYHHEAGVTALSQDPQR[166.11].L sp|Q86XL3|ANKL2_HUMAN 1 2252.085 1.89 117269 13411 3 2252.082376 751.7023 Ankyrin repeat and LEM domain-containing protein 2 OS=Homo sapiens OX=9606 GN=ANKLE2 PE=1 SV=4 5.99 2458.4 - 258637 - - - -1.1492 - 3.147 0.569 - 213.3 1 2 0 -0.0026 20 0 0 0 4.11E+06 2.17E+06 - - - 7.6644 0.9798 221125_WJC_METTL3_EV_vs_WT_F08.13412.13412.3 0.295 Sep-36 R.R[166.11]K[136.11]PFYPALIR[166.11].Y "sp|O00746|NDKM_HUMAN,tr|Q4TT34|Q4TT34_HUMAN,tr|H0Y6J0|H0Y6J0_HUMAN,tr|F2Z2X0|F2Z2X0_HUMAN,tr|A2IDC9|A2IDC9_HUMAN" 5 1287.781 1.86 117270 13412 3 1287.779368 430.2676 "Nucleoside diphosphate kinase, mitochondrial OS=Homo sapiens OX=9606 GN=NME4 PE=1 SV=1" 11 2458.5 - 182721 - - - -1.2688 - 1.307 0.192 - 133.4 1 2 0 -0.0016 10 0 0 0 4.81E+07 2.58E+07 - - - 1.4621 0.9997 221125_WJC_METTL3_EV_vs_WT_F08.13417.13417.3 1.19E-06 14/68 K.YVHYEIDAC[160.03]MDSEAPGSK[136.11].D "sp|Q86U44|MTA70_HUMAN,tr|H0YFV6|H0YFV6_HUMAN" 2 2078.8805 0.001 117273 13417 3 2078.869991 693.9674 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 4.31 2459.2 - 360437 - - - -5.0513 - 2.657 0.574 - 181.1 1 2 0 -0.0105 18 0 0 0 0.00E+00 4.84E+06 - - - 7.3699 0.9997 221125_WJC_METTL3_EV_vs_WT_F08.13422.13422.4 1.43E-05 17/90 K.MSSSEEESK[136.11]IDLLDR[166.11]K[136.11].E "sp|P54577|SYYC_HUMAN,tr|A0A6Q8PFX2|A0A6Q8PFX2_HUMAN" 2 1891.9407 0.65 117278 13422 4 1891.944389 473.9925 "Tyrosine--tRNA ligase, cytoplasmic OS=Homo sapiens OX=9606 GN=YARS1 PE=1 SV=4" 4.51 2459.8 - 392880 - - - 1.9351 - 3.095 0.475 - 277.5 1 2 1 0.0037 16 0 0 0 1.31E+07 2.01E+07 - - - 3.7574 1 221125_WJC_METTL3_EV_vs_WT_F08.13428.13428.4 2.75E-06 16/102 K.YVHYEIDAC[160.03]MDSEAPGSK[136.11].D "sp|Q86U44|MTA70_HUMAN,tr|H0YFV6|H0YFV6_HUMAN" 2 2078.8805 0.03 117282 13428 4 2078.880585 520.7274 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 4.31 2460.5 - 1.12E+06 - - - 0.0447 - 2.751 0.603 - 184.7 1 2 0 0.0001 18 0 0 0 6.16E+05 1.86E+07 - - - 4.8211 0.9999 221125_WJC_METTL3_EV_vs_WT_F08.13429.13429.4 9.97E-05 14/108 R.QGDFESDHSGYVR[166.11]PVPVPR[166.11].S sp|A6NHR9|SMHD1_HUMAN 1 2161.0456 2.4 117283 13429 4 2161.047238 541.2687 Structural maintenance of chromosomes flexible hinge domain-containing protein 1 OS=Homo sapiens OX=9606 GN=SMCHD1 PE=1 SV=2 5.38 2460.6 - 1.61E+06 - - - 0.7783 - 2.237 0.411 - 117.8 1 2 0 0.0017 19 0 0 0 6.70E+07 2.79E+07 - - - 3.0752 1 221125_WJC_METTL3_EV_vs_WT_F08.13431.13431.3 2.33E-10 18/76 K.VKVEEEEEEKVAEEEETSVK.K sp|Q9Y2X3|NOP58_HUMAN 1 2348.1119 1.38 117285 13431 3 2348.117749 783.7112 Nucleolar protein 58 OS=Homo sapiens OX=9606 GN=NOP58 PE=1 SV=1 4.12 2460.8 - 505136 - - - 2.5071 - 3.798 0.738 - 402.2 1 2 2 0.0059 20 0 0 0 1.79E+07 1.30E+07 - - - 10.0038 1 221125_WJC_METTL3_EV_vs_WT_F08.13432.13432.3 7.93E-10 14/76 K.VK[136.11]VEEEEEEK[136.11]VAEEEETSVK[136.11].K sp|Q9Y2X3|NOP58_HUMAN 1 2372.1545 1.38 117286 13432 3 2372.151068 791.7254 Nucleolar protein 58 OS=Homo sapiens OX=9606 GN=NOP58 PE=1 SV=1 4.12 2460.9 - 401306 - - - -1.4308 - 3.117 0.66 - 215.2 1 2 2 -0.0034 20 0 0 0 1.79E+07 1.30E+07 - - - 8.6555 0.9997 221125_WJC_METTL3_EV_vs_WT_F08.13433.13433.3 0.027 Dec-80 R.VSEVEEEK[136.11]EPVPQPLPSDDTR[166.11].V sp|O43290|SNUT1_HUMAN 1 2397.1666 4.27 117287 13433 3 2397.170195 800.0628 U4\U6.U5 tri-snRNP-associated protein 1 OS=Homo sapiens OX=9606 GN=SART1 PE=1 SV=1 4 2461.1 - 256660 - - - 1.4851 - 2.337 0.491 - 102.9 1 2 1 0.0036 21 0 0 0 1.82E+07 4.26E+06 - - - 6.0483 0.841 221125_WJC_METTL3_EV_vs_WT_F08.13434.13434.3 0.000878 Sep-84 R.PAAMISQPPTPPTGQPVREDAK.W sp|Q6PKG0|LARP1_HUMAN 1 2287.1631 3.9 117288 13434 3 2287.170665 763.395 La-related protein 1 OS=Homo sapiens OX=9606 GN=LARP1 PE=1 SV=2 6.49 2461.2 - 189452 - - - 3.322 - 2.3 0.439 - 74.6 1 1 1 0.0076 22 0 0 0 2.44E+06 6.25E+05 - - - 5.407 0.9999 221125_WJC_METTL3_EV_vs_WT_F08.13438.13438.4 5.04E-06 16/90 K.MSSSEEESKIDLLDRK.E "sp|P54577|SYYC_HUMAN,tr|A0A6Q8PFX2|A0A6Q8PFX2_HUMAN" 2 1865.9041 0.65 117290 13438 4 1865.903625 467.4833 "Tyrosine--tRNA ligase, cytoplasmic OS=Homo sapiens OX=9606 GN=YARS1 PE=1 SV=4" 4.51 2461.7 - 526878 - - - -0.2321 - 2.908 0.502 - 261.2 1 2 1 -0.0004 16 0 0 0 1.31E+07 2.01E+07 - - - 3.9713 1 221125_WJC_METTL3_EV_vs_WT_F08.13439.13439.3 1.60E-09 22/84 R.EAIQC[160.03]VDNNQSVLVSAHTSAGK[136.11].T sp|P42285|MTREX_HUMAN 1 2335.1318 0.78 117291 13439 3 2335.132499 779.3845 Exosome RNA helicase MTR4 OS=Homo sapiens OX=9606 GN=MTREX PE=1 SV=3 5.32 2461.8 - 1.24E+06 - - - 0.3109 - 3.719 0.625 - 489.7 1 2 0 0.0007 22 0 0 0 1.31E+07 1.68E+07 - - - 8.6219 1 221125_WJC_METTL3_EV_vs_WT_F08.13440.13440.4 4.55E-08 15/90 K.NWEEGGYFNTDKPHPR.G "sp|O95573|ACSL3_HUMAN,tr|A0A7P0TB52|A0A7P0TB52_HUMAN,tr|A0A7P0TA76|A0A7P0TA76_HUMAN,tr|A0A7P0T8L6|A0A7P0T8L6_HUMAN" 4 1945.8707 1.17 117292 13440 4 1945.870328 487.475 Fatty acid CoA ligase Acsl3 OS=Homo sapiens OX=9606 GN=ACSL3 PE=1 SV=3 5.45 2462 - 403900 - - - -0.2035 - 2.908 0.556 - 155 1 2 0 -0.0004 16 0 0 0 1.16E+07 9.87E+06 - - - 4.4413 0.9998 221125_WJC_METTL3_EV_vs_WT_F08.13441.13441.3 5.87E-05 14/56 R.K[136.11]YPSIIVNC[160.03]VEEK[136.11]PK[136.11].E sp|Q9H0D6|XRN2_HUMAN 1 1827.0027 1.16 117293 13441 3 1827.003161 610.0082 5'-3' exoribonuclease 2 OS=Homo sapiens OX=9606 GN=XRN2 PE=1 SV=1 8.16 2462.1 - 403795 - - - 0.2759 - 2.127 0.366 - 189.2 1 2 0 0.0005 15 0 0 0 2.14E+07 1.85E+07 - - - 4.5897 0.9999 221125_WJC_METTL3_EV_vs_WT_F08.13444.13444.4 6.27E-05 15/108 K.GEDSVPDTVHHVVVPVNPK.T "sp|Q92499|DDX1_HUMAN,tr|A0A7I2V2M5|A0A7I2V2M5_HUMAN,tr|A0A087X2G1|A0A087X2G1_HUMAN,tr|A0A7I2V430|A0A7I2V430_HUMAN,tr|A0A7I2V4F0|A0A7I2V4F0_HUMAN,tr|A0A7I2V4J3|A0A7I2V4J3_HUMAN,tr|A0A087WZ71|A0A087WZ71_HUMAN,tr|A0A7I2YQ77|A0A7I2YQ77_HUMAN" 8 2024.0327 1.58 117296 13444 4 2024.035092 507.0155 ATP-dependent RNA helicase DDX1 OS=Homo sapiens OX=9606 GN=DDX1 PE=1 SV=2 5.21 2462.5 - 341374 - - - 1.1798 - 2.648 0.45 - 169.1 1 2 0 0.0024 19 0 0 0 1.67E+08 1.06E+08 - - - 3.4716 0.9999 221125_WJC_METTL3_EV_vs_WT_F08.13452.13452.4 3.75E-05 Nov-84 R.DVDIIDHHDNTYTVK.Y "sp|P21333|FLNA_HUMAN,tr|A0A7P0NMY4|A0A7P0NMY4_HUMAN,tr|Q60FE5|Q60FE5_HUMAN" 3 1783.8377 0.06 117302 13452 4 1783.836697 446.9667 Filamin-A OS=Homo sapiens OX=9606 GN=FLNA PE=1 SV=4 4.54 2463.4 - 942678 - - - -0.5583 - 2.274 0.432 - 65.4 1 2 0 -0.001 15 0 0 0 4.54E+07 7.87E+08 - - - 3.2798 1 221125_WJC_METTL3_EV_vs_WT_F08.13453.13453.4 1.32E-09 20/90 K.NWEEGGYFNTDK[136.11]PHPR[166.11].G "sp|O95573|ACSL3_HUMAN,tr|A0A7P0TB52|A0A7P0TB52_HUMAN,tr|A0A7P0TA76|A0A7P0TA76_HUMAN,tr|A0A7P0T8L6|A0A7P0T8L6_HUMAN" 4 1963.8932 1.17 117303 13453 4 1963.894673 491.9806 Fatty acid CoA ligase Acsl3 OS=Homo sapiens OX=9606 GN=ACSL3 PE=1 SV=3 5.45 2463.6 - 848740 - - - 0.7531 - 3.509 0.66 - 304.1 1 2 0 0.0015 16 0 0 0 1.16E+07 9.87E+06 - - - 5.4124 1 221125_WJC_METTL3_EV_vs_WT_F08.13454.13454.3 0.000365 13/56 R.DVDIIDHHDNTYTVK.Y "sp|P21333|FLNA_HUMAN,tr|A0A7P0NMY4|A0A7P0NMY4_HUMAN,tr|Q60FE5|Q60FE5_HUMAN" 3 1783.8377 1.95 117304 13454 3 1783.837227 595.6198 Filamin-A OS=Homo sapiens OX=9606 GN=FLNA PE=1 SV=4 4.54 2463.6 - 1.33E+06 - - - -0.2612 - 2.557 0.448 - 128.7 1 2 0 -0.0005 15 0 0 0 6.69E+07 3.44E+07 - - - 5.9844 0.9999 221125_WJC_METTL3_EV_vs_WT_F08.13456.13456.4 0.000171 16/108 K.GEDSVPDTVHHVVVPVNPK[136.11].T "sp|Q92499|DDX1_HUMAN,tr|A0A7I2V2M5|A0A7I2V2M5_HUMAN,tr|A0A087X2G1|A0A087X2G1_HUMAN,tr|A0A7I2V430|A0A7I2V430_HUMAN,tr|A0A7I2V4F0|A0A7I2V4F0_HUMAN,tr|A0A7I2V4J3|A0A7I2V4J3_HUMAN,tr|A0A087WZ71|A0A087WZ71_HUMAN,tr|A0A7I2YQ77|A0A7I2YQ77_HUMAN" 8 2032.0469 1.59 117306 13456 4 2032.048191 509.019 ATP-dependent RNA helicase DDX1 OS=Homo sapiens OX=9606 GN=DDX1 PE=1 SV=2 5.21 2463.9 - 463960 - - - 0.6334 - 2.757 0.442 - 204.2 1 2 0 0.0013 19 0 0 0 1.67E+08 1.05E+08 - - - 3.4159 1 221125_WJC_METTL3_EV_vs_WT_F08.13458.13458.3 1.13E-07 13/84 K.QVC[160.03]GDSIK[136.11]PEETEQEVAADETR[166.11].N sp|Q96GM8|TOE1_HUMAN 1 2508.1405 1.34 117308 13458 3 2508.137776 837.0541 Target of EGR1 protein 1 OS=Homo sapiens OX=9606 GN=TOE1 PE=1 SV=1 4 2464.1 - 281558 - - - -1.0849 - 2.588 0.682 - 179.7 1 2 0 -0.0027 22 0 0 0 5.28E+06 3.93E+06 - - - 8.3973 1 221125_WJC_METTL3_EV_vs_WT_F08.13460.13460.3 1.19E-08 19/72 K.TEELNKEVASNSELVQSSR.S "sp|P08779|K1C16_HUMAN,tr|K7ENW6|K7ENW6_HUMAN" 2 2119.0393 999 117309 13460 3 2119.044682 707.3537 "Keratin, type I cytoskeletal 16 OS=Homo sapiens OX=9606 GN=KRT16 PE=1 SV=4" 4.49 2464.4 - 1.86E+06 - - - 2.537 - 3.881 0.616 - 487.6 1 2 1 0.0054 19 0 0 0 4.97E+07 0.00E+00 - - - 8.738 1 221125_WJC_METTL3_EV_vs_WT_F08.13461.13461.3 3.94E-07 17/68 K.ANELPQPPVPEPANAGKR.K "sp|P78347|GTF2I_HUMAN,tr|A0A494C1K3|A0A494C1K3_HUMAN" 2 1883.9854 1.97 117310 13461 3 1883.986766 629.0024 General transcription factor II-I OS=Homo sapiens OX=9606 GN=GTF2I PE=1 SV=2 6.19 2464.4 - 1.24E+06 - - - 0.7463 - 2.908 0.608 - 223.9 1 2 0 0.0014 18 0 0 0 1.06E+08 5.36E+07 - - - 7.9763 1 221125_WJC_METTL3_EV_vs_WT_F08.13462.13462.3 5.86E-09 19/52 K.HEK[136.11]EDGAISTIVLR[166.11].G sp|P50990|TCPQ_HUMAN 1 1584.859 0.38 117311 13462 3 1584.858305 529.2936 T-complex protein 1 subunit theta OS=Homo sapiens OX=9606 GN=CCT8 PE=1 SV=4 5.45 2464.5 - 1.27E+06 - - - -0.4638 - 3.106 0.617 - 536.7 1 2 1 -0.0007 14 0 0 0 2.89E+08 7.65E+08 - - - 8.4306 1 221125_WJC_METTL3_EV_vs_WT_F08.13463.13463.4 6.86E-07 18/90 R.QATINIGTIGHVAHGK.S "sp|Q2VIR3|IF2GL_HUMAN,sp|P41091|IF2G_HUMAN,tr|H7BZU1|H7BZU1_HUMAN" 3 1615.8794 0.93 117312 13463 4 1615.877162 404.9771 Eukaryotic translation initiation factor 2 subunit 3B OS=Homo sapiens OX=9606 GN=EIF2S3B PE=2 SV=2 8.76 2464.7 - 689514 - - - -1.4085 - 3.071 0.486 - 377 1 2 0 -0.0023 16 0 0 0 2.19E+08 2.37E+08 - - - 3.8507 1 221125_WJC_METTL3_EV_vs_WT_F08.13465.13465.3 7.10E-11 14/72 R.YGAQC[160.03]TSAHSQEELAEWQK.R "sp|P42694|HELZ_HUMAN,tr|J3QS41|J3QS41_HUMAN,tr|A0A075B6R3|A0A075B6R3_HUMAN" 3 2221.9698 3.82 117314 13465 3 2221.965134 741.6639 Probable helicase with zinc finger domain OS=Homo sapiens OX=9606 GN=HELZ PE=1 SV=2 4.75 2464.9 - 502663 - - - -2.1206 - 3.214 0.695 - 193.6 1 2 0 -0.0047 19 0 0 0 1.17E+07 3.06E+06 - - - 9.1556 1 221125_WJC_METTL3_EV_vs_WT_F08.13467.13467.3 1.40E-10 17/84 R.EAIQC[160.03]VDNNQSVLVSAHTSAGK.T sp|P42285|MTREX_HUMAN 1 2327.1176 0.78 117315 13467 3 2327.118868 776.7131 Exosome RNA helicase MTR4 OS=Homo sapiens OX=9606 GN=MTREX PE=1 SV=3 5.32 2465.1 - 853750 - - - 0.5565 - 3.21 0.682 - 388.7 1 2 0 0.0013 22 0 0 0 1.31E+07 1.68E+07 - - - 8.9083 0.9997 221125_WJC_METTL3_EV_vs_WT_F08.13470.13470.4 1.25E-06 18/90 R.QATINIGTIGHVAHGK[136.11].S "sp|Q2VIR3|IF2GL_HUMAN,sp|P41091|IF2G_HUMAN,tr|H7BZU1|H7BZU1_HUMAN" 3 1623.8936 0.93 117317 13470 4 1623.887734 406.9807 Eukaryotic translation initiation factor 2 subunit 3B OS=Homo sapiens OX=9606 GN=EIF2S3B PE=2 SV=2 8.76 2465.4 - 1.48E+06 - - - -3.6357 - 3.796 0.449 - 386.7 1 2 0 -0.0059 16 0 0 0 2.19E+08 2.37E+08 - - - 3.6024 1 221125_WJC_METTL3_EV_vs_WT_F08.13472.13472.4 4.07E-09 19/108 K.TMEPEEEVEDDPKVHLEAK.E sp|O15119|TBX3_HUMAN 1 2224.0205 0.95 117319 13472 4 2224.019931 557.0124 T-box transcription factor TBX3 OS=Homo sapiens OX=9606 GN=TBX3 PE=1 SV=4 4.16 2465.6 - 1.12E+06 - - - -0.2756 - 3.201 0.627 - 234.9 1 2 1 -0.0006 19 0 0 0 7.86E+07 8.26E+07 - - - 5.0768 0.9998 221125_WJC_METTL3_EV_vs_WT_F08.13473.13473.3 1.48E-07 15/52 K.HEKEDGAISTIVLR.G sp|P50990|TCPQ_HUMAN 1 1566.8366 0.38 117320 13473 3 1566.83311 523.2861 T-complex protein 1 subunit theta OS=Homo sapiens OX=9606 GN=CCT8 PE=1 SV=4 5.45 2465.7 - 873395 - - - -2.2083 - 2.751 0.542 - 336.7 1 2 1 -0.0035 14 0 0 0 2.89E+08 7.65E+08 - - - 7.2711 0.9997 221125_WJC_METTL3_EV_vs_WT_F08.13477.13477.3 2.23E-06 13/52 K.DGIEPMWEDEKNKR.G "sp|P06730|IF4E_HUMAN,tr|H0Y8J7|H0Y8J7_HUMAN,tr|D6RBW1|D6RBW1_HUMAN" 3 1745.8043 6.93 117322 13477 3 1745.800119 582.942 Eukaryotic translation initiation factor 4E OS=Homo sapiens OX=9606 GN=EIF4E PE=1 SV=2 4.51 2466.3 - 597043 - - - -2.3857 - 2.595 0.519 - 160.7 1 2 1 -0.0042 14 0 0 0 1.07E+07 1.55E+06 - - - 6.8594 0.9999 221125_WJC_METTL3_EV_vs_WT_F08.13478.13478.3 1.20E-09 16/72 K.GEDSVPDTVHHVVVPVNPK.T "sp|Q92499|DDX1_HUMAN,tr|A0A7I2V2M5|A0A7I2V2M5_HUMAN,tr|A0A087X2G1|A0A087X2G1_HUMAN,tr|A0A7I2V430|A0A7I2V430_HUMAN,tr|A0A7I2V4F0|A0A7I2V4F0_HUMAN,tr|A0A7I2V4J3|A0A7I2V4J3_HUMAN,tr|A0A087WZ71|A0A087WZ71_HUMAN,tr|A0A7I2YQ77|A0A7I2YQ77_HUMAN" 8 2024.0327 1.56 117323 13478 3 2024.024202 675.6848 ATP-dependent RNA helicase DDX1 OS=Homo sapiens OX=9606 GN=DDX1 PE=1 SV=2 5.21 2466.4 - 613473 - - - -4.2005 - 3.115 0.609 - 327.8 1 2 0 -0.0085 19 0 0 0 7.96E+07 5.11E+07 - - - 8.1189 1 221125_WJC_METTL3_EV_vs_WT_F08.13483.13483.2 1.92E-07 18/32 R.AQVQEFC[160.03]DYGTKEEC[160.03]MK[136.11].A "sp|Q86U44|MTA70_HUMAN,tr|H0YFV6|H0YFV6_HUMAN" 2 2129.8948 - 117326 13483 2 2130.883244 1065.9547 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 4.41 2467 - 449136 - - - 464.0985 - 3.833 0.722 - 750.1 1 2 1 0.9885 17 0 0 0 - - - - - 7.3667 0.9981 221125_WJC_METTL3_EV_vs_WT_F08.13487.13487.4 1.42E-05 16/78 K.HEK[136.11]EDGAISTIVLR[166.11].G sp|P50990|TCPQ_HUMAN 1 1584.859 0.42 117328 13487 4 1584.85199 397.222 T-complex protein 1 subunit theta OS=Homo sapiens OX=9606 GN=CCT8 PE=1 SV=4 5.45 2467.5 - 762312 - - - -4.4483 - 2.668 0.46 - 161 1 2 1 -0.0071 14 0 0 0 3.50E+07 8.32E+07 - - - 3.585 1 221125_WJC_METTL3_EV_vs_WT_F08.13490.13490.4 1.40E-08 19/96 R.AQVQEFC[160.03]DYGTK[136.11]EEC[160.03]MK[136.11].A "sp|Q86U44|MTA70_HUMAN,tr|H0YFV6|H0YFV6_HUMAN" 2 2137.909 0.001 117329 13490 4 2137.899452 535.4845 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 4.41 2467.9 - 1.63E+06 - - - -4.4487 - 3.819 0.678 - 322.5 1 2 1 -0.0095 17 0 0 0 0.00E+00 6.89E+07 - - - 5.5899 1 221125_WJC_METTL3_EV_vs_WT_F08.13491.13491.3 4.47E-06 20/80 K.SPAVATSTAAPPPPSSPLPSK.S "sp|Q14157|UBP2L_HUMAN,tr|F8W726|F8W726_HUMAN" 2 1959.0313 3.34 117330 13491 3 1959.029152 654.0177 Ubiquitin-associated protein 2-like OS=Homo sapiens OX=9606 GN=UBAP2L PE=1 SV=2 8.47 2468.1 - 605952 - - - -1.1 - 3.525 0.541 - 587.2 1 2 0 -0.0022 21 0 0 0 1.45E+08 4.33E+07 - - - 7.5915 1 221125_WJC_METTL3_EV_vs_WT_F08.13492.13492.2 1.48E-11 16/28 Q.VQEFC[160.03]DYGTK[136.11]EEC[160.03]MK[136.11].A "sp|Q86U44|MTA70_HUMAN,tr|H0YFV6|H0YFV6_HUMAN" 2 1938.8133 0.001 117331 13492 2 1938.805165 970.4139 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 4.41 2468.2 - 617337 - - - -4.1809 - 3.361 0.704 - 689.9 1 1 1 -0.0081 15 0 0 0 0.00E+00 3.08E+07 - - - 7.2185 0.9947 221125_WJC_METTL3_EV_vs_WT_F08.13508.13508.2 5.63E-06 14/26 K.HEK[136.11]EDGAISTIVLR[166.11].G sp|P50990|TCPQ_HUMAN 1 1584.859 0.21 117339 13508 2 1584.855177 793.4368 T-complex protein 1 subunit theta OS=Homo sapiens OX=9606 GN=CCT8 PE=1 SV=4 5.45 2470.1 - 1.26E+06 - - - -2.4374 - 1.859 0.515 - 260.1 1 2 1 -0.0039 14 0 0 0 7.16E+06 3.41E+07 - - - 4.3995 0.9996 221125_WJC_METTL3_EV_vs_WT_F08.13513.13513.4 4.36E-05 18/78 K.HEKEDGAISTIVLR.G sp|P50990|TCPQ_HUMAN 1 1566.8366 0.42 117341 13513 4 1566.833177 392.7164 T-complex protein 1 subunit theta OS=Homo sapiens OX=9606 GN=CCT8 PE=1 SV=4 5.45 2470.8 - 1.82E+06 - - - -2.1655 - 2.422 0.449 - 200.8 1 2 1 -0.0034 14 0 0 0 3.50E+07 8.32E+07 - - - 3.4551 1 221125_WJC_METTL3_EV_vs_WT_F08.13517.13517.3 3.76E-09 16/64 R.AQVQEFC[160.03]DYGTKEEC[160.03]MK.A "sp|Q86U44|MTA70_HUMAN,tr|H0YFV6|H0YFV6_HUMAN" 2 2121.8806 0.01 117343 13517 3 2122.879367 708.3008 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 4.41 2471.3 - 5.99E+06 - - - 470.7164 - 3.235 0.678 - 252.2 1 2 1 0.9988 17 0 0 0 2.42E+08 3.41E+10 - - - 8.7883 0.9515 221125_WJC_METTL3_EV_vs_WT_F08.13522.13522.3 0.0361 Aug-36 K.KKWNLDELPK.F "sp|P17844|DDX5_HUMAN,tr|J3QR02|J3QR02_HUMAN,tr|X6RLV5|X6RLV5_HUMAN,tr|A0A7I2V507|A0A7I2V507_HUMAN,tr|J3KTA4|J3KTA4_HUMAN,tr|J3KTQ4|J3KTQ4_HUMAN,tr|A0A7I2V2S0|A0A7I2V2S0_HUMAN,tr|J3QRQ7|J3QRQ7_HUMAN" 8 1269.7081 1.86 117345 13522 3 1269.703362 424.2433 Probable ATP-dependent RNA helicase DDX5 OS=Homo sapiens OX=9606 GN=DDX5 PE=1 SV=1 8.5 2472 - 799500 - - - -3.7489 - 1.598 0.272 - 131.3 1 2 1 -0.0048 10 0 0 0 2.40E+07 1.29E+07 - - - 2.9402 0.9996 221125_WJC_METTL3_EV_vs_WT_F08.13529.13529.4 4.45E-07 20/96 K.AAVKDVEEEKFPTQLSR.H sp|Q2TAY7|SMU1_HUMAN 1 1946.0109 0.97 117347 13529 4 1946.007034 487.51 WD40 repeat-containing protein SMU1 OS=Homo sapiens OX=9606 GN=SMU1 PE=1 SV=2 4.87 2473 - 1.97E+06 - - - -1.9897 - 3.723 0.424 - 317.1 1 2 2 -0.0039 17 0 0 0 5.88E+07 6.06E+07 - - - 3.3718 1 221125_WJC_METTL3_EV_vs_WT_F08.13530.13530.3 5.98E-14 26/64 K.AAVKDVEEEKFPTQLSR.H sp|Q2TAY7|SMU1_HUMAN 1 1946.0109 1 117348 13530 3 1946.010144 649.6776 WD40 repeat-containing protein SMU1 OS=Homo sapiens OX=9606 GN=SMU1 PE=1 SV=2 4.87 2473.1 - 1.73E+06 - - - -0.3916 - 4.242 0.68 - 656 1 2 2 -0.0008 17 0 0 0 8.38E+07 8.38E+07 - - - 9.7717 1 221125_WJC_METTL3_EV_vs_WT_F08.13534.13534.3 2.67E-10 28/64 K.AAVK[136.11]DVEEEK[136.11]FPTQLSR[166.11].H sp|Q2TAY7|SMU1_HUMAN 1 1972.0476 1 117350 13534 3 1972.048204 658.3565 WD40 repeat-containing protein SMU1 OS=Homo sapiens OX=9606 GN=SMU1 PE=1 SV=2 4.87 2473.7 - 2.18E+06 - - - 0.3185 - 4.739 0.603 - 812.8 1 2 2 0.0006 17 0 0 0 8.38E+07 8.38E+07 - - - 9.1932 1 221125_WJC_METTL3_EV_vs_WT_F08.13535.13535.2 2.72E-12 20/40 K.SPAVATSTAAPPPPSSPLPSK.S "sp|Q14157|UBP2L_HUMAN,tr|F8W726|F8W726_HUMAN" 2 1959.0313 4.65 117351 13535 2 1959.027991 980.5229 Ubiquitin-associated protein 2-like OS=Homo sapiens OX=9606 GN=UBAP2L PE=1 SV=2 8.47 2473.8 - 897206 - - - -1.6927 - 4.071 0.619 - 630.8 1 2 0 -0.0033 21 0 0 0 4.57E+07 9.83E+06 - - - 7.0634 0.8204 221125_WJC_METTL3_EV_vs_WT_F08.13545.13545.3 0.012 Oct-64 A.KC[160.03]PPHSSTQEDGSMNC[160.03]R[166.11].C "sp|P29320|EPHA3_HUMAN,tr|C9JXA2|C9JXA2_HUMAN" 2 1999.8174 - 117356 13545 3 1999.814934 667.6131 Ephrin type-A receptor 3 OS=Homo sapiens OX=9606 GN=EPHA3 PE=1 SV=2 6.73 2475 - 1.57E+06 - - - -1.2326 - 1.537 0.292 - 43.7 1 1 0 -0.0025 17 0 0 0 - - - - - 2.8807 1 221125_WJC_METTL3_EV_vs_WT_F08.13553.13553.3 1.99E-08 17/72 K.GEDSVPDTVHHVVVPVNPK[136.11].T "sp|Q92499|DDX1_HUMAN,tr|A0A7I2V2M5|A0A7I2V2M5_HUMAN,tr|A0A087X2G1|A0A087X2G1_HUMAN,tr|A0A7I2V430|A0A7I2V430_HUMAN,tr|A0A7I2V4F0|A0A7I2V4F0_HUMAN,tr|A0A7I2V4J3|A0A7I2V4J3_HUMAN,tr|A0A087WZ71|A0A087WZ71_HUMAN,tr|A0A7I2YQ77|A0A7I2YQ77_HUMAN" 8 2032.0469 1.56 117361 13553 3 2032.042567 678.3562 ATP-dependent RNA helicase DDX1 OS=Homo sapiens OX=9606 GN=DDX1 PE=1 SV=2 5.21 2476 - 1.55E+06 - - - -2.1343 - 2.704 0.596 - 374.7 1 2 0 -0.0043 19 0 0 0 7.99E+07 5.12E+07 - - - 7.6275 1 221125_WJC_METTL3_EV_vs_WT_F08.13559.13559.3 9.42E-11 20/64 K.SSYLPNSDPLHQSDTSK.A "sp|O75179|ANR17_HUMAN,tr|H0YM23|H0YM23_HUMAN" 2 1874.8646 2.94 117365 13559 3 1874.861775 625.9622 Ankyrin repeat domain-containing protein 17 OS=Homo sapiens OX=9606 GN=ANKRD17 PE=1 SV=3 5.19 2476.8 - 866242 - - - -1.526 - 2.838 0.638 - 299 1 2 0 -0.0029 17 0 0 0 8.70E+07 2.96E+07 - - - 8.2875 1 221125_WJC_METTL3_EV_vs_WT_F08.13565.13565.3 3.30E-07 17/68 K.ANELPQPPVPEPANAGK[136.11]R[166.11].K "sp|P78347|GTF2I_HUMAN,tr|A0A494C1K3|A0A494C1K3_HUMAN" 2 1902.0078 1.98 117369 13565 3 1902.004842 635.0099 General transcription factor II-I OS=Homo sapiens OX=9606 GN=GTF2I PE=1 SV=2 6.19 2477.6 - 1.33E+06 - - - -1.571 - 2.771 0.537 - 254.8 1 2 0 -0.003 18 0 0 0 1.05E+08 5.29E+07 - - - 7.0641 1 221125_WJC_METTL3_EV_vs_WT_F08.13566.13566.3 0.00131 19/56 R.LQAQQDAVNIVC[160.03]HSK[136.11].T "sp|P55036|PSMD4_HUMAN,tr|A6PVX3|A6PVX3_HUMAN,tr|Q5VWC4|Q5VWC4_HUMAN" 3 1717.8661 1.49 117370 13566 3 1717.866892 573.6293 26S proteasome non-ATPase regulatory subunit 4 OS=Homo sapiens OX=9606 GN=PSMD4 PE=1 SV=1 6.73 2477.7 - 816986 - - - 0.4593 - 3.209 0.477 - 781.1 1 2 0 0.0008 15 0 0 0 1.74E+07 1.17E+07 - - - 6.9003 1 221125_WJC_METTL3_EV_vs_WT_F08.13572.13572.3 3.12E-12 25/112 R.LGPASAADTGSEAK[136.11]PGALAEGAAEPEPQR[166.11].H "sp|Q9NYB0|TE2IP_HUMAN,tr|A0A590UJT3|A0A590UJT3_HUMAN" 2 2765.3587 1.09 117374 13572 3 2766.356219 922.7935 Telomeric repeat-binding factor 2-interacting protein 1 OS=Homo sapiens OX=9606 GN=TERF2IP PE=1 SV=1 4.25 2478.5 - 548654 - - - 360.7246 - 4.396 0.664 - 562.8 1 2 0 0.9975 29 0 0 0 1.09E+07 9.97E+06 - - - 9.0732 1 221125_WJC_METTL3_EV_vs_WT_F08.13575.13575.3 3.39E-08 20/108 R.QLASAGTGPC[160.03]PVHPASNGTSPAPALPAR.A sp|Q6ICC9|RTL6_HUMAN 1 2681.3344 9.15 117377 13575 3 2681.330127 894.7854 Retrotransposon Gag-like protein 6 OS=Homo sapiens OX=9606 GN=RTL6 PE=2 SV=1 8.26 2478.9 - 749149 - - - -1.5873 - 3.763 0.637 - 304.3 1 2 0 -0.0043 28 0 0 0 1.47E+07 1.61E+06 - - - 8.6896 1 221125_WJC_METTL3_EV_vs_WT_F08.13576.13576.3 4.52E-08 17/52 K.HHNQPYC[160.03]GIAPYIR.E sp|P08621|RU17_HUMAN 1 1724.8205 1.09 117378 13576 3 1724.818954 575.9475 U1 small nuclear ribonucleoprotein 70 kDa OS=Homo sapiens OX=9606 GN=SNRNP70 PE=1 SV=2 8.21 2479 - 690830 - - - -0.9213 - 3.351 0.545 - 478.3 1 2 0 -0.0016 14 0 0 0 1.37E+07 1.27E+07 - - - 7.8294 1 221125_WJC_METTL3_EV_vs_WT_F08.13580.13580.4 1.84E-11 22/108 R.ALVDHENVISC[160.03]PHLGASTK.E "sp|O43175|SERA_HUMAN,tr|A0A286YF78|A0A286YF78_HUMAN,tr|A0A2C9F2M7|A0A2C9F2M7_HUMAN,tr|A0A286YF22|A0A286YF22_HUMAN,tr|A0A286YFL2|A0A286YFL2_HUMAN,tr|A0A286YFA2|A0A286YFA2_HUMAN" 6 2047.0157 1.44 117380 13580 4 2047.012986 512.7612 D-3-phosphoglycerate dehydrogenase OS=Homo sapiens OX=9606 GN=PHGDH PE=1 SV=4 5.99 2479.5 - 3.66E+06 - - - -1.3131 - 3.907 0.625 - 321.6 1 2 0 -0.0027 19 0 0 0 2.56E+08 1.77E+08 - - - 5.1263 1 221125_WJC_METTL3_EV_vs_WT_F08.13581.13581.3 5.79E-11 30/72 R.ALVDHENVISC[160.03]PHLGASTK[136.11].E "sp|O43175|SERA_HUMAN,tr|A0A286YF78|A0A286YF78_HUMAN,tr|A0A2C9F2M7|A0A2C9F2M7_HUMAN,tr|A0A286YF22|A0A286YF22_HUMAN,tr|A0A286YFL2|A0A286YFL2_HUMAN,tr|A0A286YFA2|A0A286YFA2_HUMAN" 6 2055.0299 1.12 117381 13581 3 2055.027031 686.0172 D-3-phosphoglycerate dehydrogenase OS=Homo sapiens OX=9606 GN=PHGDH PE=1 SV=4 5.99 2479.7 - 1.08E+06 - - - -1.3834 - 4.373 0.612 - 1418.9 1 2 0 -0.0028 19 0 0 0 1.01E+08 9.04E+07 - - - 8.9873 1 221125_WJC_METTL3_EV_vs_WT_F08.13582.13582.3 4.56E-06 25/96 R.NMGGPYGGGNYGPGGSGGSGGYGGR[166.11].S "sp|P22626|ROA2_HUMAN,tr|A0A024RA28|A0A024RA28_HUMAN,tr|A0A7I2V4N1|A0A7I2V4N1_HUMAN,tr|A0A7I2V4I6|A0A7I2V4I6_HUMAN,tr|A0A7I2V323|A0A7I2V323_HUMAN,tr|A0A7I2V3P1|A0A7I2V3P1_HUMAN" 6 2198.9063 1.03 117382 13582 3 2198.904199 733.9761 Heterogeneous nuclear ribonucleoproteins A2\B1 OS=Homo sapiens OX=9606 GN=HNRNPA2B1 PE=1 SV=2 8.5 2479.8 - 1.77E+06 - - - -0.9773 - 4.539 0.617 - 791 1 2 0 -0.0021 25 0 0 0 3.21E+07 3.13E+07 - - - 8.8985 1 221125_WJC_METTL3_EV_vs_WT_F08.13583.13583.3 1.30E-07 21/52 R.HQAQIDHYLGLANK.N "sp|Q9NQC3|RTN4_HUMAN,tr|F8W914|F8W914_HUMAN,tr|H7C106|H7C106_HUMAN" 3 1606.8216 1.13 117383 13583 3 1606.821466 536.6145 Reticulon-4 OS=Homo sapiens OX=9606 GN=RTN4 PE=1 SV=2 6.92 2479.9 - 1.49E+06 - - - -0.0765 - 3.493 0.587 - 685.5 1 2 0 -0.0001 14 0 0 0 5.68E+07 5.04E+07 - - - 8.4084 1 221125_WJC_METTL3_EV_vs_WT_F08.13584.13584.3 3.53E-12 20/52 R.HQAQIDHYLGLANK[136.11].N "sp|Q9NQC3|RTN4_HUMAN,tr|F8W914|F8W914_HUMAN,tr|H7C106|H7C106_HUMAN" 3 1614.8358 1.12 117384 13584 3 1614.83684 539.2859 Reticulon-4 OS=Homo sapiens OX=9606 GN=RTN4 PE=1 SV=2 6.92 2480 - 1.31E+06 - - - 0.6508 - 3.483 0.615 - 596.3 1 2 0 0.0011 14 0 0 0 5.66E+07 5.04E+07 - - - 8.7127 1 221125_WJC_METTL3_EV_vs_WT_F08.13585.13585.3 5.36E-09 30/72 R.ALVDHENVISC[160.03]PHLGASTK.E "sp|O43175|SERA_HUMAN,tr|A0A286YF78|A0A286YF78_HUMAN,tr|A0A2C9F2M7|A0A2C9F2M7_HUMAN,tr|A0A286YF22|A0A286YF22_HUMAN,tr|A0A286YFL2|A0A286YFL2_HUMAN,tr|A0A286YFA2|A0A286YFA2_HUMAN" 6 2047.0157 1.13 117385 13585 3 2047.01595 683.3458 D-3-phosphoglycerate dehydrogenase OS=Homo sapiens OX=9606 GN=PHGDH PE=1 SV=4 5.99 2480.1 - 1.10E+06 - - - 0.1348 - 5.179 0.672 - 1453.6 1 2 0 0.0003 19 0 0 0 1.02E+08 9.07E+07 - - - 10.0725 1 221125_WJC_METTL3_EV_vs_WT_F08.13589.13589.4 1.63E-10 20/108 R.ALVDHENVISC[160.03]PHLGASTK[136.11].E "sp|O43175|SERA_HUMAN,tr|A0A286YF78|A0A286YF78_HUMAN,tr|A0A2C9F2M7|A0A2C9F2M7_HUMAN,tr|A0A286YF22|A0A286YF22_HUMAN,tr|A0A286YFL2|A0A286YFL2_HUMAN,tr|A0A286YFA2|A0A286YFA2_HUMAN" 6 2055.0299 1.44 117387 13589 4 2055.025542 514.7647 D-3-phosphoglycerate dehydrogenase OS=Homo sapiens OX=9606 GN=PHGDH PE=1 SV=4 5.99 2480.6 - 4.92E+06 - - - -2.108 - 3.45 0.562 - 265.6 1 2 0 -0.0043 19 0 0 0 2.56E+08 1.77E+08 - - - 4.5354 1 221125_WJC_METTL3_EV_vs_WT_F08.13590.13590.3 1.77E-13 26/64 R.EIAGHIMEFSQDQHGSR.F "sp|Q14671|PUM1_HUMAN,tr|Q5T1Z8|Q5T1Z8_HUMAN,tr|H0YDK8|H0YDK8_HUMAN,tr|H0YEH2|H0YEH2_HUMAN,tr|Q5T1Z4|Q5T1Z4_HUMAN,tr|E9PR38|E9PR38_HUMAN" 6 1940.8799 2.05 117388 13590 3 1940.875557 647.9672 Pumilio homolog 1 OS=Homo sapiens OX=9606 GN=PUM1 PE=1 SV=3 5.28 2480.7 - 2.44E+06 - - - -2.2423 - 4.404 0.708 - 1073.6 1 2 0 -0.0044 17 0 0 0 1.26E+08 6.13E+07 - - - 10.1776 1 221125_WJC_METTL3_EV_vs_WT_F08.13591.13591.4 2.27E-10 24/96 R.EIAGHIMEFSQDQHGSR.F "sp|Q14671|PUM1_HUMAN,tr|Q5T1Z8|Q5T1Z8_HUMAN,tr|H0YDK8|H0YDK8_HUMAN,tr|H0YEH2|H0YEH2_HUMAN,tr|Q5T1Z4|Q5T1Z4_HUMAN,tr|E9PR38|E9PR38_HUMAN" 6 1940.8799 2 117389 13591 4 1940.877566 486.2273 Pumilio homolog 1 OS=Homo sapiens OX=9606 GN=PUM1 PE=1 SV=3 5.28 2480.8 - 2.07E+06 - - - -1.2072 - 3.649 0.616 - 515.4 1 2 0 -0.0023 17 0 0 0 1.04E+08 5.21E+07 - - - 5.0364 1 221125_WJC_METTL3_EV_vs_WT_F08.13593.13593.3 7.34E-13 30/64 R.EIAGHIMEFSQDQHGSR[166.11].F "sp|Q14671|PUM1_HUMAN,tr|Q5T1Z8|Q5T1Z8_HUMAN,tr|H0YDK8|H0YDK8_HUMAN,tr|H0YEH2|H0YEH2_HUMAN,tr|Q5T1Z4|Q5T1Z4_HUMAN,tr|E9PR38|E9PR38_HUMAN" 6 1950.8882 2.07 117391 13593 3 1950.886743 651.3033 Pumilio homolog 1 OS=Homo sapiens OX=9606 GN=PUM1 PE=1 SV=3 5.28 2481 - 1.48E+06 - - - -0.7361 - 4.526 0.659 - 1425.3 1 2 0 -0.0014 17 0 0 0 1.29E+08 6.23E+07 - - - 9.7011 0.9994 221125_WJC_METTL3_EV_vs_WT_F08.13595.13595.4 2.03E-05 13/78 K.GKPIFEVNKQDIYK.S "sp|Q6P3W7|SCYL2_HUMAN,tr|F8VSC5|F8VSC5_HUMAN,tr|A0A0U1RQQ9|A0A0U1RQQ9_HUMAN" 3 1677.909 1.8 117393 13595 4 1677.905448 420.4845 SCY1-like protein 2 OS=Homo sapiens OX=9606 GN=SCYL2 PE=1 SV=1 8.43 2481.2 - 668815 - - - -2.1211 - 2.238 0.429 - 81.9 1 2 1 -0.0036 14 0 0 0 1.01E+07 5.63E+06 - - - 3.2522 1 221125_WJC_METTL3_EV_vs_WT_F08.13596.13596.3 2.73E-10 18/52 K.HHNQPYC[160.03]GIAPYIR[166.11].E sp|P08621|RU17_HUMAN 1 1734.8288 3.91 117394 13596 3 1734.827487 579.2835 U1 small nuclear ribonucleoprotein 70 kDa OS=Homo sapiens OX=9606 GN=SNRNP70 PE=1 SV=2 8.21 2481.3 - 539941 - - - -0.7643 - 3.406 0.629 - 616.9 1 2 0 -0.0013 14 0 0 0 6.02E+07 1.54E+07 - - - 8.8093 0.9901 221125_WJC_METTL3_EV_vs_WT_F08.13598.13598.4 0.0489 Dec-78 K.GK[136.11]PIFEVNK[136.11]QDIYK[136.11].S "sp|Q6P3W7|SCYL2_HUMAN,tr|F8VSC5|F8VSC5_HUMAN,tr|A0A0U1RQQ9|A0A0U1RQQ9_HUMAN" 3 1701.9516 1.8 117396 13598 4 1701.947627 426.4952 SCY1-like protein 2 OS=Homo sapiens OX=9606 GN=SCYL2 PE=1 SV=1 8.43 2481.6 - 376287 - - - -2.3385 - 2.099 0.28 - 78.5 1 2 1 -0.004 14 0 0 0 1.01E+07 5.63E+06 - - - 1.9319 1 221125_WJC_METTL3_EV_vs_WT_F08.13602.13602.4 1.82E-05 18/96 R.EIAGHIMEFSQDQHGSR[166.11].F "sp|Q14671|PUM1_HUMAN,tr|Q5T1Z8|Q5T1Z8_HUMAN,tr|H0YDK8|H0YDK8_HUMAN,tr|H0YEH2|H0YEH2_HUMAN,tr|Q5T1Z4|Q5T1Z4_HUMAN,tr|E9PR38|E9PR38_HUMAN" 6 1950.8882 2 117398 13602 4 1950.885351 488.7293 Pumilio homolog 1 OS=Homo sapiens OX=9606 GN=PUM1 PE=1 SV=3 5.28 2482.1 - 2.19E+06 - - - -1.4496 - 3.091 0.565 - 226.4 1 2 0 -0.0028 17 0 0 0 1.04E+08 5.21E+07 - - - 4.5348 0.9999 221125_WJC_METTL3_EV_vs_WT_F08.13604.13604.3 4.41E-06 14/68 K.IQSNDGKELDINNQVVPK.N "sp|Q6P4E1|GOLM2_HUMAN,tr|A0A3B3IRW9|A0A3B3IRW9_HUMAN,tr|H0YMR0|H0YMR0_HUMAN,tr|H0YM51|H0YM51_HUMAN" 4 2010.0382 3.22 117400 13604 3 2010.038197 671.02 Protein GOLM2 OS=Homo sapiens OX=9606 GN=GOLM2 PE=1 SV=2 4.56 2482.3 - 1.26E+06 - - - 0.0065 - 3.097 0.534 - 144.8 1 2 1 0 18 0 0 0 1.73E+07 5.39E+06 - - - 7.3085 1 221125_WJC_METTL3_EV_vs_WT_F08.13605.13605.4 1.76E-09 18/78 R.HQAQIDHYLGLANK[136.11].N "sp|Q9NQC3|RTN4_HUMAN,tr|F8W914|F8W914_HUMAN,tr|H7C106|H7C106_HUMAN" 3 1614.8358 1 117401 13605 4 1614.831806 404.7162 Reticulon-4 OS=Homo sapiens OX=9606 GN=RTN4 PE=1 SV=2 6.92 2482.4 - 1.16E+06 - - - -2.4665 - 3.233 0.594 - 357.3 1 2 0 -0.004 14 0 0 0 1.53E+07 1.54E+07 - - - 4.8221 1 221125_WJC_METTL3_EV_vs_WT_F08.13606.13606.4 3.64E-09 19/78 R.HQAQIDHYLGLANK.N "sp|Q9NQC3|RTN4_HUMAN,tr|F8W914|F8W914_HUMAN,tr|H7C106|H7C106_HUMAN" 3 1606.8216 1 117402 13606 4 1606.820565 402.7127 Reticulon-4 OS=Homo sapiens OX=9606 GN=RTN4 PE=1 SV=2 6.92 2482.5 - 1.05E+06 - - - -0.6373 - 3.406 0.592 - 438.5 1 2 0 -0.001 14 0 0 0 1.53E+07 1.54E+07 - - - 4.8245 1 221125_WJC_METTL3_EV_vs_WT_F08.13607.13607.3 9.82E-07 21/80 K.SPAVATSTAAPPPPSSPLPSK[136.11].S "sp|Q14157|UBP2L_HUMAN,tr|F8W726|F8W726_HUMAN" 2 1967.0455 3.36 117403 13607 3 1967.04453 656.6891 Ubiquitin-associated protein 2-like OS=Homo sapiens OX=9606 GN=UBAP2L PE=1 SV=2 8.47 2482.6 - 698960 - - - -0.4967 - 3.803 0.52 - 594 1 2 0 -0.001 21 0 0 0 1.44E+08 4.28E+07 - - - 7.5397 0.8801 221125_WJC_METTL3_EV_vs_WT_F08.13609.13609.4 0.00883 Dec-66 R.QQELDNLLHEK[136.11]R[166.11].Y "sp|Q12788|TBL3_HUMAN,tr|J3KNP2|J3KNP2_HUMAN" 2 1539.8124 0.98 117405 13609 4 1539.808916 385.9604 Transducin beta-like protein 3 OS=Homo sapiens OX=9606 GN=TBL3 PE=1 SV=2 5.45 2482.9 - 356120 - - - -2.2788 - 1.856 0.12 - 110.3 1 2 0 -0.0035 12 0 0 0 3.48E+06 3.54E+06 - - - 0.5035 1 221125_WJC_METTL3_EV_vs_WT_F08.13610.13610.4 3.93E-05 13/66 R.QQELDNLLHEKR.Y "sp|Q12788|TBL3_HUMAN,tr|J3KNP2|J3KNP2_HUMAN" 2 1521.79 0.99 117406 13610 4 1521.789808 381.4548 Transducin beta-like protein 3 OS=Homo sapiens OX=9606 GN=TBL3 PE=1 SV=2 5.45 2483 - 343274 - - - -0.0966 - 2.388 0.495 - 136.3 1 2 0 -0.0001 12 0 0 0 3.48E+06 3.51E+06 - - - 3.8639 0.9944 221125_WJC_METTL3_EV_vs_WT_F08.13611.13611.3 0.00488 Aug-52 K.GK[136.11]PIFEVNK[136.11]QDIYK[136.11].S "sp|Q6P3W7|SCYL2_HUMAN,tr|F8VSC5|F8VSC5_HUMAN,tr|A0A0U1RQQ9|A0A0U1RQQ9_HUMAN" 3 1701.9516 2.69 117407 13611 3 1701.949079 568.3245 SCY1-like protein 2 OS=Homo sapiens OX=9606 GN=SCYL2 PE=1 SV=1 8.43 2483.1 - 328273 - - - -1.4854 - 1.589 0.333 - 33.7 2 2 1 -0.0025 14 0 0 0 1.14E+07 4.24E+06 - - - 3.3433 1 221125_WJC_METTL3_EV_vs_WT_F08.13613.13613.3 8.21E-05 16/72 R.GTGSHPWTMAPPPGSTPSR[166.11].T "sp|O43347|MSI1H_HUMAN,tr|H0YHB7|H0YHB7_HUMAN" 2 1929.9031 1.61 117408 13613 3 1929.901948 644.3083 RNA-binding protein Musashi homolog 1 OS=Homo sapiens OX=9606 GN=MSI1 PE=1 SV=1 9.76 2483.3 - 7.85E+06 - - - -0.5969 - 2.501 0.527 - 298.2 1 2 0 -0.0012 19 0 0 0 3.52E+08 2.19E+08 - - - 6.6673 1 221125_WJC_METTL3_EV_vs_WT_F08.13616.13616.3 5.00E-13 26/112 R.LGPASAADTGSEAKPGALAEGAAEPEPQR.H "sp|Q9NYB0|TE2IP_HUMAN,tr|A0A590UJT3|A0A590UJT3_HUMAN" 2 2747.3362 1.09 117410 13616 3 2747.337188 916.786 Telomeric repeat-binding factor 2-interacting protein 1 OS=Homo sapiens OX=9606 GN=TERF2IP PE=1 SV=1 4.25 2483.7 - 848583 - - - 0.3538 - 4.676 0.722 - 575.8 1 2 0 0.001 29 0 0 0 1.09E+07 9.97E+06 - - - 10.1379 1 221125_WJC_METTL3_EV_vs_WT_F08.13618.13618.3 8.68E-06 24/96 R.NMGGPYGGGNYGPGGSGGSGGYGGR.S "sp|P22626|ROA2_HUMAN,tr|A0A024RA28|A0A024RA28_HUMAN,tr|A0A7I2V4N1|A0A7I2V4N1_HUMAN,tr|A0A7I2V4I6|A0A7I2V4I6_HUMAN,tr|A0A7I2V323|A0A7I2V323_HUMAN,tr|A0A7I2V3P1|A0A7I2V3P1_HUMAN" 6 2188.8981 1 117412 13618 3 2188.897485 730.64 Heterogeneous nuclear ribonucleoproteins A2\B1 OS=Homo sapiens OX=9606 GN=HNRNPA2B1 PE=1 SV=2 8.5 2483.9 - 1.24E+06 - - - -0.2709 - 3.988 0.645 - 485.8 1 2 0 -0.0006 25 0 0 0 3.21E+07 3.21E+07 - - - 8.9134 1 221125_WJC_METTL3_EV_vs_WT_F08.13621.13621.3 4.38E-06 16/80 K.VGVGTC[160.03]GIADKPMTQYQDTSK.Y sp|O75940|SPF30_HUMAN 1 2255.0562 0.89 117415 13621 3 2255.052286 752.6927 Survival of motor neuron-related-splicing factor 30 OS=Homo sapiens OX=9606 GN=SMNDC1 PE=1 SV=1 5.92 2484.3 - 318381 - - - -1.7436 - 2.893 0.535 - 261.8 1 2 0 -0.0039 21 0 0 0 2.77E+06 3.10E+06 - - - 7.0504 1 221125_WJC_METTL3_EV_vs_WT_F08.13627.13627.3 8.46E-13 22/68 K.SEHTQTVSQLTSQNEVLR[166.11].N sp|Q8IWJ2|GCC2_HUMAN 1 2066.0268 4.3 117419 13627 3 2066.025388 689.6829 GRIP and coiled-coil domain-containing protein 2 OS=Homo sapiens OX=9606 GN=GCC2 PE=1 SV=4 5.38 2485.1 - 1.18E+06 - - - -0.6742 - 4.045 0.607 - 694.3 1 2 0 -0.0014 18 0 0 0 1.08E+08 2.50E+07 - - - 8.7869 0.9996 221125_WJC_METTL3_EV_vs_WT_F08.13629.13629.4 2.03E-06 17/102 K.VK[136.11]EDPDQGESMK[136.11]PLTFAR[166.11].F "sp|Q68CQ7|GL8D1_HUMAN,tr|C9J880|C9J880_HUMAN" 2 2073.0411 49.65 117421 13629 4 2073.038034 519.2676 Glycosyltransferase 8 domain-containing protein 1 OS=Homo sapiens OX=9606 GN=GLT8D1 PE=1 SV=2 4.78 2485.3 - 438866 - - - -1.4843 - 2.235 0.42 - 120 1 2 1 -0.0031 18 0 0 0 2.55E+08 5.13E+06 - - - 3.1563 1 221125_WJC_METTL3_EV_vs_WT_F08.13635.13635.4 5.47E-09 16/90 R.DSDSGLEQMSIGHHIR.D sp|Q15773|MLF2_HUMAN 1 1780.8162 0.19 117425 13635 4 1780.814548 446.2113 Myeloid leukemia factor 2 OS=Homo sapiens OX=9606 GN=MLF2 PE=1 SV=1 5.21 2486 - 1.01E+06 - - - -0.9535 - 2.89 0.605 - 245 1 2 0 -0.0017 16 0 0 0 1.55E+07 8.15E+07 - - - 4.8653 0.9999 221125_WJC_METTL3_EV_vs_WT_F08.13636.13636.4 1.04E-09 21/102 R.DVQNFPAATDEKDKFVEK.M "sp|O60610|DIAP1_HUMAN,tr|A0A2R8Y5N1|A0A2R8Y5N1_HUMAN,tr|A0A140T8Z0|A0A140T8Z0_HUMAN,tr|A0A0G2JH68|A0A0G2JH68_HUMAN,tr|H9KV28|H9KV28_HUMAN" 5 2080.0113 0.77 117426 13636 4 2080.012877 521.0101 Protein diaphanous homolog 1 OS=Homo sapiens OX=9606 GN=DIAPH1 PE=1 SV=2 4.44 2486.1 - 786038 - - - 0.7582 - 3.823 0.599 - 319.3 1 2 2 0.0016 18 0 0 0 9.42E+06 1.23E+07 - - - 4.8986 1 221125_WJC_METTL3_EV_vs_WT_F08.13637.13637.3 1.33E-10 20/60 R.DSDSGLEQMSIGHHIR.D sp|Q15773|MLF2_HUMAN 1 1780.8162 0.19 117427 13637 3 1780.808259 594.6127 Myeloid leukemia factor 2 OS=Homo sapiens OX=9606 GN=MLF2 PE=1 SV=1 5.21 2486.3 - 767559 - - - -4.485 - 3.427 0.682 - 686.2 1 2 0 -0.008 16 0 0 0 1.34E+07 7.24E+07 - - - 9.3018 0.9184 221125_WJC_METTL3_EV_vs_WT_F08.13646.13646.3 0.0435 Oct-56 R.HQSIHTGEKPFEC[160.03]NK.C sp|Q96SK3|ZN607_HUMAN 1 1810.8421 999 117434 13646 3 1811.847582 604.6213 Zinc finger protein 607 OS=Homo sapiens OX=9606 GN=ZNF607 PE=1 SV=3 6.91 2487.4 - 487889 - - - 555.2748 - 1.851 0.252 - 73.2 1 2 0 1.0055 15 0 0 0 2.07E+07 0.00E+00 - - - 2.6777 1 221125_WJC_METTL3_EV_vs_WT_F08.13652.13652.3 4.60E-15 18/104 K.NTVC[160.03]PEQSEALAGGSAGDGAQAAGVTK[136.11].E "sp|Q8N1G0|ZN687_HUMAN,tr|A2A3Q2|A2A3Q2_HUMAN,tr|F8WCX2|F8WCX2_HUMAN" 3 2553.1857 0.84 117438 13652 3 2553.185163 852.0692 Zinc finger protein 687 OS=Homo sapiens OX=9606 GN=ZNF687 PE=1 SV=1 4.14 2488.2 - 547637 - - - -0.1943 - 4.153 0.749 - 338.2 1 2 0 -0.0005 27 0 0 0 5.40E+06 6.42E+06 - - - 10.1662 1 221125_WJC_METTL3_EV_vs_WT_F08.13653.13653.3 4.56E-13 15/104 K.NTVC[160.03]PEQSEALAGGSAGDGAQAAGVTK.E "sp|Q8N1G0|ZN687_HUMAN,tr|A2A3Q2|A2A3Q2_HUMAN,tr|F8WCX2|F8WCX2_HUMAN" 3 2545.1715 0.84 117439 13653 3 2545.168067 849.3978 Zinc finger protein 687 OS=Homo sapiens OX=9606 GN=ZNF687 PE=1 SV=1 4.14 2488.3 - 499147 - - - -1.3327 - 3.623 0.705 - 151.9 1 2 0 -0.0034 27 0 0 0 5.40E+06 6.42E+06 - - - 9.3607 0.9968 221125_WJC_METTL3_EV_vs_WT_F08.13654.13654.3 0.00378 14/68 R.DVQNFPAATDEKDKFVEK.M "sp|O60610|DIAP1_HUMAN,tr|A0A2R8Y5N1|A0A2R8Y5N1_HUMAN,tr|A0A140T8Z0|A0A140T8Z0_HUMAN,tr|A0A0G2JH68|A0A0G2JH68_HUMAN,tr|H9KV28|H9KV28_HUMAN" 5 2080.0113 1.18 117440 13654 3 2080.005444 694.3444 Protein diaphanous homolog 1 OS=Homo sapiens OX=9606 GN=DIAPH1 PE=1 SV=2 4.44 2488.4 - 491713 - - - -2.8154 - 2.384 0.341 - 153 1 2 2 -0.0059 18 0 0 0 5.48E+06 4.66E+06 - - - 4.5035 1 221125_WJC_METTL3_EV_vs_WT_F08.13661.13661.3 9.17E-13 19/64 L.VDHENVISC[160.03]PHLGASTK.E "sp|O43175|SERA_HUMAN,tr|A0A286YF78|A0A286YF78_HUMAN,tr|A0A2C9F2M7|A0A2C9F2M7_HUMAN,tr|A0A286YF22|A0A286YF22_HUMAN,tr|A0A286YFL2|A0A286YFL2_HUMAN,tr|A0A286YFA2|A0A286YFA2_HUMAN" 6 1862.8945 1.46 117445 13661 3 1862.898701 621.9721 D-3-phosphoglycerate dehydrogenase OS=Homo sapiens OX=9606 GN=PHGDH PE=1 SV=4 5.99 2489.4 - 406075 - - - 2.2572 - 3.894 0.634 - 643.1 1 1 0 0.0042 17 0 0 0 6.87E+06 4.72E+06 - - - 9.0417 1 221125_WJC_METTL3_EV_vs_WT_F08.13662.13662.4 515 4/132 S.GC[160.03]GGC[160.03]GSSC[160.03]GGC[160.03]GSGC[160.03]GGC[160.03]GSGR[166.11].G sp|Q701N4|KRA52_HUMAN 1 2176.6895 0.02 117446 13662 4 2176.681316 545.1797 Keratin-associated protein 5-2 OS=Homo sapiens OX=9606 GN=KRTAP5-2 PE=1 SV=1 7.78 2489.5 - 378917 - - - -3.7667 - 0.521 0.808 - 7.8 1 1 0 -0.0082 23 0 0 0 2.05E+05 9.58E+06 - - - 6.0453 1 221125_WJC_METTL3_EV_vs_WT_F08.13668.13668.3 6.31E-07 17/64 R.EC[160.03]GQAFSQSSNLLQHQR[166.11].V sp|Q9H7X3|ZN696_HUMAN 1 1998.9205 1.22 117450 13668 3 1998.919092 667.3141 Zinc finger protein 696 OS=Homo sapiens OX=9606 GN=ZNF696 PE=1 SV=2 6.84 2490.3 - 616351 - - - -0.7254 - 3.433 0.61 - 483.5 1 2 0 -0.0014 17 0 0 0 1.64E+07 1.34E+07 - - - 8.4565 1 221125_WJC_METTL3_EV_vs_WT_F08.13670.13670.4 1.04E-06 15/120 K.TSLIMNPHASTNGQLSVHTPK.R "sp|Q9H334|FOXP1_HUMAN,tr|C9J5T4|C9J5T4_HUMAN,tr|A0A3B3ISQ6|A0A3B3ISQ6_HUMAN,tr|A0A3B3IRW5|A0A3B3IRW5_HUMAN,tr|G5E965|G5E965_HUMAN,tr|A0A3B3IRS5|A0A3B3IRS5_HUMAN,tr|A0A3B3IST0|A0A3B3IST0_HUMAN,tr|A0A3B3IT14|A0A3B3IT14_HUMAN,tr|C9J0F0|C9J0F0_HUMAN,tr|A0A3B3IU15|A0A3B3IU15_HUMAN,tr|A0A3B3IUB6|A0A3B3IUB6_HUMAN,tr|H0Y882|H0Y882_HUMAN,tr|A0A3B3IT66|A0A3B3IT66_HUMAN,tr|A0A3B3IS87|A0A3B3IS87_HUMAN,tr|A0A087X2G3|A0A087X2G3_HUMAN,tr|A0A0B4J2F3|A0A0B4J2F3_HUMAN,tr|A0A3B3IU08|A0A3B3IU08_HUMAN,tr|A0A3B3IST6|A0A3B3IST6_HUMAN,tr|A0A3B3IT26|A0A3B3IT26_HUMAN" 19 2232.1321 4.17 117452 13670 4 2232.133606 559.0403 Forkhead box protein P1 OS=Homo sapiens OX=9606 GN=FOXP1 PE=1 SV=1 8.47 2490.5 - 1.23E+06 - - - 0.6742 - 3.134 0.49 - 113.7 1 2 0 0.0015 21 0 0 0 3.79E+07 9.09E+06 - - - 3.8682 1 221125_WJC_METTL3_EV_vs_WT_F08.13674.13674.3 8.12E-09 16/88 R.NSVER[166.11]PAEPVAGAATPSLVEQQK[136.11].M sp|Q9BTC0|DIDO1_HUMAN 1 2395.2462 0.39 117456 13674 3 2395.248494 799.4227 Death-inducer obliterator 1 OS=Homo sapiens OX=9606 GN=DIDO1 PE=1 SV=5 4.79 2491 - 266395 - - - 0.9481 - 3.687 0.585 - 167.6 1 2 0 0.0023 23 0 0 0 1.22E+06 3.16E+06 - - - 8.1226 1 221125_WJC_METTL3_EV_vs_WT_F08.13682.13682.3 6.72E-08 22/80 K.QAAASATQTIAAAQHAASTPK[136.11].A sp|Q9Y490|TLN1_HUMAN 1 2002.0323 1.22 117462 13682 3 2002.031269 668.3514 Talin-1 OS=Homo sapiens OX=9606 GN=TLN1 PE=1 SV=3 8.76 2491.9 - 966079 - - - -0.5235 - 4.479 0.618 - 631.8 1 2 0 -0.001 21 0 0 0 5.36E+07 4.40E+07 - - - 9.0245 1 221125_WJC_METTL3_EV_vs_WT_F08.13683.13683.3 1.19E-08 23/80 K.QAAASATQTIAAAQHAASTPK.A sp|Q9Y490|TLN1_HUMAN 1 1994.0181 1.23 117463 13683 3 1994.020303 665.68 Talin-1 OS=Homo sapiens OX=9606 GN=TLN1 PE=1 SV=3 8.76 2492.1 - 928089 - - - 1.0963 - 4.443 0.539 - 614.4 1 2 0 0.0022 21 0 0 0 5.40E+07 4.40E+07 - - - 8.1241 0.9998 221125_WJC_METTL3_EV_vs_WT_F08.13687.13687.3 0.000315 13/56 R.K[136.11]YPSIIVNC[160.03]VEEK[136.11]PK[136.11].E sp|Q9H0D6|XRN2_HUMAN 1 1827.0027 0.4 117466 13687 3 1827.000457 610.0082 5'-3' exoribonuclease 2 OS=Homo sapiens OX=9606 GN=XRN2 PE=1 SV=1 8.16 2492.5 - 252525 - - - -1.2042 - 1.792 0.433 - 180 1 2 0 -0.0022 15 0 0 0 2.32E+06 5.80E+06 - - - 4.889 1 221125_WJC_METTL3_EV_vs_WT_F08.13689.13689.4 1.28E-05 14/96 K.TGTIVVEGHELHDEDIR[166.11].L "sp|P41252|SYIC_HUMAN,tr|A0A804HL54|A0A804HL54_HUMAN,tr|A0A804HIV9|A0A804HIV9_HUMAN,tr|A0A804HJN6|A0A804HJN6_HUMAN,tr|A0A804HHW9|A0A804HHW9_HUMAN,tr|A0A0A0MSX9|A0A0A0MSX9_HUMAN,tr|J3KR24|J3KR24_HUMAN,tr|A0A804HJ36|A0A804HJ36_HUMAN" 8 1928.9467 1.16 117467 13689 4 1928.94607 483.244 "Isoleucine--tRNA ligase, cytoplasmic OS=Homo sapiens OX=9606 GN=IARS1 PE=1 SV=2" 4.49 2492.8 - 617200 - - - -0.3468 - 2.929 0.469 - 131.5 1 2 0 -0.0007 17 0 0 0 1.74E+07 1.50E+07 - - - 3.6811 0.9998 221125_WJC_METTL3_EV_vs_WT_F08.13691.13691.4 4.77E-06 15/114 K.SLIGVEYKPVSATGAEDKDK.K sp|P07814|SYEP_HUMAN 1 2106.0845 0.9 117469 13691 4 2106.087974 527.5284 Bifunctional glutamate\proline--tRNA ligase OS=Homo sapiens OX=9606 GN=EPRS1 PE=1 SV=5 4.78 2493 - 1.55E+06 - - - 1.6661 - 2.874 0.491 - 71.6 1 2 1 0.0035 20 0 0 0 2.18E+07 2.42E+07 - - - 3.8516 1 221125_WJC_METTL3_EV_vs_WT_F08.13697.13697.2 3.46E-06 15/26 K.VQALEEANNDLENK.L sp|P35527|K1C9_HUMAN 1 1585.7584 999 117475 13697 2 1585.760972 793.8865 "Keratin, type I cytoskeletal 9 OS=Homo sapiens OX=9606 GN=KRT9 PE=1 SV=3" 4 2493.7 - 347883 - - - 1.6345 - 2.88 0.638 - 693.7 1 2 0 0.0026 14 0 0 0 1.29E+07 0.00E+00 - - - 6.4069 0.9989 221125_WJC_METTL3_EV_vs_WT_F08.13698.13698.3 0.00691 Sep-44 R.HVFLTGPPGVGK[136.11].T "sp|Q9BSD7|NTPCR_HUMAN,tr|Q5TDF0|Q5TDF0_HUMAN" 2 1215.6855 0.94 117476 13698 3 1215.6838 406.2358 Cancer-related nucleoside-triphosphatase OS=Homo sapiens OX=9606 GN=NTPCR PE=1 SV=1 8.76 2493.9 - 323702 - - - -1.4338 - 1.57 0.321 - 71.9 1 2 0 -0.0017 12 0 0 0 2.05E+06 2.17E+06 - - - 3.3687 1 221125_WJC_METTL3_EV_vs_WT_F08.13701.13701.4 4.19E-10 20/96 K.TGTIVVEGHELHDEDIR.L "sp|P41252|SYIC_HUMAN,tr|A0A804HL54|A0A804HL54_HUMAN,tr|A0A804HIV9|A0A804HIV9_HUMAN,tr|A0A804HJN6|A0A804HJN6_HUMAN,tr|A0A804HHW9|A0A804HHW9_HUMAN,tr|A0A0A0MSX9|A0A0A0MSX9_HUMAN,tr|J3KR24|J3KR24_HUMAN,tr|A0A804HJ36|A0A804HJ36_HUMAN" 8 1918.9385 1.18 117477 13701 4 1918.941046 480.7419 "Isoleucine--tRNA ligase, cytoplasmic OS=Homo sapiens OX=9606 GN=IARS1 PE=1 SV=2" 4.49 2494.3 - 1.14E+06 - - - 1.3429 - 3.765 0.635 - 259.5 1 2 0 0.0026 17 0 0 0 1.74E+07 1.48E+07 - - - 5.2126 1 221125_WJC_METTL3_EV_vs_WT_F08.13709.13709.3 5.44E-07 18/68 K.ANELPQPPVPEPANAGKR.K "sp|P78347|GTF2I_HUMAN,tr|A0A494C1K3|A0A494C1K3_HUMAN" 2 1883.9854 1.85 117484 13709 3 1883.989235 629.0024 General transcription factor II-I OS=Homo sapiens OX=9606 GN=GTF2I PE=1 SV=2 6.19 2495.3 - 5.59E+06 - - - 2.0568 - 2.843 0.566 - 272.5 1 2 0 0.0039 18 0 0 0 3.62E+08 1.96E+08 - - - 7.4511 1 221125_WJC_METTL3_EV_vs_WT_F08.13712.13712.3 7.35E-06 17/72 R.GTGSHPWTMAPPPGSTPSR.T "sp|O43347|MSI1H_HUMAN,tr|H0YHB7|H0YHB7_HUMAN" 2 1919.8948 1.58 117486 13712 3 1919.894887 640.9722 RNA-binding protein Musashi homolog 1 OS=Homo sapiens OX=9606 GN=MSI1 PE=1 SV=1 9.76 2495.6 - 2.33E+06 - - - 0.0297 - 3.292 0.511 - 306 1 2 0 0.0001 19 0 0 0 3.54E+08 2.24E+08 - - - 7.1644 1 221125_WJC_METTL3_EV_vs_WT_F08.13716.13716.3 5.02E-08 22/64 R.AQVQEFC[160.03]DYGTK[136.11]EEC[160.03]MK[136.11].A "sp|Q86U44|MTA70_HUMAN,tr|H0YFV6|H0YFV6_HUMAN" 2 2137.909 0.13 117490 13716 3 2137.908404 713.6436 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 4.41 2495.9 - 1.42E+06 - - - -0.2615 - 3.663 0.674 - 478.7 1 2 1 -0.0006 17 0 0 0 4.15E+06 3.15E+07 - - - 9.3341 0.9523 221125_WJC_METTL3_EV_vs_WT_F08.13717.13717.3 4.50E-06 13/60 R.GSDIKDLTVC[160.03]EPPKPQ.C "sp|Q8ND56|LS14A_HUMAN,tr|I3L4Q1|I3L4Q1_HUMAN,tr|A0A140TA76|A0A140TA76_HUMAN,tr|K7EMZ9|K7EMZ9_HUMAN" 4 1782.8822 11.82 117491 13717 3 1782.885625 595.3013 Protein LSM14 homolog A OS=Homo sapiens OX=9606 GN=LSM14A PE=1 SV=3 4.56 2496 - 1.07E+06 - - - 1.921 - 2.41 0.447 - 184.1 1 1 1 0.0034 16 0 0 0 2.84E+07 2.41E+06 - - - 5.7797 0.9979 221125_WJC_METTL3_EV_vs_WT_F08.13718.13718.3 0.00235 20/84 R.TQSSASLAASYAAQQHPQAAAS.Y sp|Q96PK6|RBM14_HUMAN 1 2145.0087 - 117492 13718 3 2145.010545 716.0102 RNA-binding protein 14 OS=Homo sapiens OX=9606 GN=RBM14 PE=1 SV=2 6.4 2496.1 - 788519 - - - 0.8723 - 3.75 0.491 - 279.6 1 1 0 0.0019 22 0 0 0 - - - - - 7.1473 1 221125_WJC_METTL3_EV_vs_WT_F08.13722.13722.3 2.27E-06 Sep-80 K.TSLIMNPHASTNGQLSVHTPK.R "sp|Q9H334|FOXP1_HUMAN,tr|C9J5T4|C9J5T4_HUMAN,tr|A0A3B3ISQ6|A0A3B3ISQ6_HUMAN,tr|A0A3B3IRW5|A0A3B3IRW5_HUMAN,tr|G5E965|G5E965_HUMAN,tr|A0A3B3IRS5|A0A3B3IRS5_HUMAN,tr|A0A3B3IST0|A0A3B3IST0_HUMAN,tr|A0A3B3IT14|A0A3B3IT14_HUMAN,tr|C9J0F0|C9J0F0_HUMAN,tr|A0A3B3IU15|A0A3B3IU15_HUMAN,tr|A0A3B3IUB6|A0A3B3IUB6_HUMAN,tr|H0Y882|H0Y882_HUMAN,tr|A0A3B3IT66|A0A3B3IT66_HUMAN,tr|A0A3B3IS87|A0A3B3IS87_HUMAN,tr|A0A087X2G3|A0A087X2G3_HUMAN,tr|A0A0B4J2F3|A0A0B4J2F3_HUMAN,tr|A0A3B3IU08|A0A3B3IU08_HUMAN,tr|A0A3B3IST6|A0A3B3IST6_HUMAN,tr|A0A3B3IT26|A0A3B3IT26_HUMAN" 19 2232.1321 8.26 117496 13722 3 2232.135522 745.0513 Forkhead box protein P1 OS=Homo sapiens OX=9606 GN=FOXP1 PE=1 SV=1 8.47 2496.7 - 299279 - - - 1.5326 - 2.583 0.546 - 63.9 1 2 0 0.0034 21 0 0 0 4.46E+06 5.40E+05 - - - 6.9015 1 221125_WJC_METTL3_EV_vs_WT_F08.13729.13729.3 6.43E-18 27/92 R.TQSSASLAASYAAQQHPQAAASYR.G sp|Q96PK6|RBM14_HUMAN 1 2464.1731 1.89 117501 13729 3 2464.173436 822.3983 RNA-binding protein 14 OS=Homo sapiens OX=9606 GN=RBM14 PE=1 SV=2 8.29 2497.5 - 642902 - - - 0.1307 - 5.313 0.606 - 671.2 1 2 0 0.0003 24 0 0 0 4.19E+09 2.22E+09 - - - 9.1753 0.9998 221125_WJC_METTL3_EV_vs_WT_F08.13735.13735.3 0.00124 Dec-52 R.TYSLGSALRPSTSR.S "sp|P08670|VIME_HUMAN,tr|B0YJC4|B0YJC4_HUMAN,tr|A0A1B0GVG8|A0A1B0GVG8_HUMAN,tr|A0A1B0GTT5|A0A1B0GTT5_HUMAN" 4 1494.7791 1.73 117505 13735 3 1494.780625 499.267 Vimentin OS=Homo sapiens OX=9606 GN=VIM PE=1 SV=4 10.83 2498.3 - 631573 - - - 1.0497 - 1.726 0.405 - 158 1 2 0 0.0016 14 0 0 0 8.90E+07 5.14E+07 - - - 4.5054 0.9963 221125_WJC_METTL3_EV_vs_WT_F08.13736.13736.3 0.00812 Sep-52 R.TYSLGSALR[166.11]PSTSR[166.11].S "sp|P08670|VIME_HUMAN,tr|B0YJC4|B0YJC4_HUMAN,tr|A0A1B0GVG8|A0A1B0GVG8_HUMAN,tr|A0A1B0GTT5|A0A1B0GTT5_HUMAN" 4 1514.7956 1.73 117506 13736 3 1514.795852 505.9391 Vimentin OS=Homo sapiens OX=9606 GN=VIM PE=1 SV=4 10.83 2498.5 - 556066 - - - 0.169 - 1.439 0.262 - 80.3 1 2 0 0.0003 14 0 0 0 8.89E+07 5.13E+07 - - - 2.4282 1 221125_WJC_METTL3_EV_vs_WT_F08.13737.13737.3 1.05E-11 28/92 R.TQSSASLAASYAAQQHPQAAASYR[166.11].G sp|Q96PK6|RBM14_HUMAN 1 2474.1814 1.89 117507 13737 3 2474.184942 825.7344 RNA-binding protein 14 OS=Homo sapiens OX=9606 GN=RBM14 PE=1 SV=2 8.29 2498.6 - 573032 - - - 1.4381 - 5.171 0.672 - 723.4 1 2 0 0.0036 24 0 0 0 4.19E+09 2.22E+09 - - - 9.8473 1 221125_WJC_METTL3_EV_vs_WT_F08.13741.13741.4 0.00129 14/72 K.K[136.11]QPFC[160.03]DGSHFFQR[166.11].T sp|P0C7P0|CISD3_HUMAN 1 1670.7743 0.97 117511 13741 4 1670.776806 418.7008 "CDGSH iron-sulfur domain-containing protein 3, mitochondrial OS=Homo sapiens OX=9606 GN=CISD3 PE=1 SV=1" 8.23 2499.1 - 344788 - - - 1.5209 - 2.467 0.519 - 176.3 1 2 0 0.0025 13 0 0 0 4.68E+06 4.82E+06 - - - 4.0775 1 221125_WJC_METTL3_EV_vs_WT_F08.13743.13743.3 3.07E-09 16/96 K.TPEPVVPTAPEPHPTTSTDQPVTPK.L sp|Q14676|MDC1_HUMAN 1 2622.3177 1.59 117513 13743 3 2622.318244 875.1132 Mediator of DNA damage checkpoint protein 1 OS=Homo sapiens OX=9606 GN=MDC1 PE=1 SV=3 4.65 2499.4 - 194478 - - - 0.2025 - 3.469 0.655 - 198.7 1 2 0 0.0005 25 0 0 0 3.34E+07 2.10E+07 - - - 8.7041 0.9999 221125_WJC_METTL3_EV_vs_WT_F08.13746.13746.3 0.00188 13/44 R.QSVEADINGLRR.V "sp|P13645|K1C10_HUMAN,sp|Q7Z3Y8|K1C27_HUMAN,sp|P13646|K1C13_HUMAN,tr|A0A1B0GVI3|A0A1B0GVI3_HUMAN,tr|K7EMD9|K7EMD9_HUMAN,tr|K7ERE3|K7ERE3_HUMAN" 6 1356.711 269.27 117514 13746 3 1356.710945 453.2443 "Keratin, type I cytoskeletal 10 OS=Homo sapiens OX=9606 GN=KRT10 PE=1 SV=6" 6.07 2499.8 - 3.13E+06 - - - -0.0228 - 1.988 0.393 - 276.7 1 2 0 0 12 0 0 0 1.39E+08 5.16E+05 - - - 4.8262 1 221125_WJC_METTL3_EV_vs_WT_F08.13748.13748.3 1.09E-12 24/80 D.HTPSQELALTQSVGGDSSADR[166.11].L "sp|Q86U44|MTA70_HUMAN,tr|H0YFV6|H0YFV6_HUMAN" 2 2165.0224 0.42 117516 13748 3 2165.022353 722.6814 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 4.54 2500 - 1.78E+06 - - - -0.0328 - 3.865 0.672 - 530.2 1 1 0 -0.0001 21 0 0 0 1.15E+07 2.71E+07 - - - 9.2734 1 221125_WJC_METTL3_EV_vs_WT_F08.13749.13749.4 6.34E-08 26/138 R.TQSSASLAASYAAQQHPQAAASYR[166.11].G sp|Q96PK6|RBM14_HUMAN 1 2474.1814 1.95 117517 13749 4 2474.183272 619.5526 RNA-binding protein 14 OS=Homo sapiens OX=9606 GN=RBM14 PE=1 SV=2 8.29 2500.1 - 589810 - - - 0.7631 - 4.179 0.536 - 363.1 1 2 0 0.0019 24 0 0 0 9.05E+08 4.63E+08 - - - 4.3498 1 221125_WJC_METTL3_EV_vs_WT_F08.13751.13751.3 3.29E-13 20/76 K.MHDLNTDQENLVGTHDAPIR[166.11].C "sp|O43684|BUB3_HUMAN,tr|J3QT28|J3QT28_HUMAN,tr|J3QSX4|J3QSX4_HUMAN" 3 2285.0734 0.34 117519 13751 3 2285.074013 762.6984 Mitotic checkpoint protein BUB3 OS=Homo sapiens OX=9606 GN=BUB3 PE=1 SV=1 4.63 2500.4 - 506317 - - - 0.2626 - 3.88 0.739 - 392.9 1 2 0 0.0006 20 0 0 0 7.00E+06 2.07E+07 - - - 10.0682 1 221125_WJC_METTL3_EV_vs_WT_F08.13752.13752.4 3.62E-07 16/84 R.K[136.11]AHEILPNLVC[160.03]C[160.03]SAK[136.11].N "sp|P50990|TCPQ_HUMAN,tr|H7C4C8|H7C4C8_HUMAN" 2 1754.9142 0.62 117520 13752 4 1754.916276 439.7358 T-complex protein 1 subunit theta OS=Homo sapiens OX=9606 GN=CCT8 PE=1 SV=4 8.06 2500.5 - 358398 - - - 1.1568 - 2.306 0.483 - 185.8 1 2 0 0.002 15 0 0 0 4.08E+07 6.61E+07 - - - 3.7284 1 221125_WJC_METTL3_EV_vs_WT_F08.13753.13753.4 2.33E-06 14/72 K.KQPFC[160.03]DGSHFFQR.T sp|P0C7P0|CISD3_HUMAN 1 1652.7518 0.97 117521 13753 4 1652.752555 414.1952 "CDGSH iron-sulfur domain-containing protein 3, mitochondrial OS=Homo sapiens OX=9606 GN=CISD3 PE=1 SV=1" 8.23 2500.6 - 311604 - - - 0.4598 - 2.753 0.577 - 180.4 1 2 0 0.0008 13 0 0 0 4.68E+06 4.82E+06 - - - 4.6235 1 221125_WJC_METTL3_EV_vs_WT_F08.13760.13760.3 3.33E-07 20/52 R.HQDSWNGLSHEAFR.L "sp|P38646|GRP75_HUMAN,tr|H0Y8K0|H0Y8K0_HUMAN,tr|A0A7I2V2S7|A0A7I2V2S7_HUMAN,tr|A0A7I2V2K6|A0A7I2V2K6_HUMAN,tr|A0A3B3ITI4|A0A3B3ITI4_HUMAN,tr|A0A7I2V3F7|A0A7I2V3F7_HUMAN,tr|A0A7I2YQQ5|A0A7I2YQQ5_HUMAN,tr|D6RCD7|D6RCD7_HUMAN" 8 1682.755 2.38 117526 13760 3 1682.755689 561.9256 "Stress-70 protein, mitochondrial OS=Homo sapiens OX=9606 GN=HSPA9 PE=1 SV=2" 5.99 2501.5 - 691910 - - - 0.4297 - 3.912 0.572 - 726.2 1 2 0 0.0007 14 0 0 0 1.41E+07 5.94E+06 - - - 8.542 1 221125_WJC_METTL3_EV_vs_WT_F08.13761.13761.3 9.17E-07 18/92 R.GIASTSDPPTANIK[136.11]PTPVVSTPSK[136.11].V sp|P12270|TPR_HUMAN 1 2380.2821 2.84 117527 13761 3 2380.281566 794.4346 Nucleoprotein TPR OS=Homo sapiens OX=9606 GN=TPR PE=1 SV=3 8.59 2501.6 - 436575 - - - -0.2059 - 2.691 0.53 - 218.8 1 2 0 -0.0005 24 0 0 0 7.08E+07 2.49E+07 - - - 6.748 1 221125_WJC_METTL3_EV_vs_WT_F08.13765.13765.3 6.78E-05 15/96 K.TPEPVVPTAPEPHPTTSTDQPVTPK[136.11].L sp|Q14676|MDC1_HUMAN 1 2630.3319 1.59 117531 13765 3 2630.331586 877.7846 Mediator of DNA damage checkpoint protein 1 OS=Homo sapiens OX=9606 GN=MDC1 PE=1 SV=3 4.65 2502 - 422867 - - - -0.1243 - 3.233 0.545 - 179.3 1 2 0 -0.0003 25 0 0 0 3.34E+07 2.10E+07 - - - 7.3157 1 221125_WJC_METTL3_EV_vs_WT_F08.13766.13766.3 7.32E-08 17/52 R.HQDSWNGLSHEAFR[166.11].L "sp|P38646|GRP75_HUMAN,tr|H0Y8K0|H0Y8K0_HUMAN,tr|A0A7I2V2S7|A0A7I2V2S7_HUMAN,tr|A0A7I2V2K6|A0A7I2V2K6_HUMAN,tr|A0A3B3ITI4|A0A3B3ITI4_HUMAN,tr|A0A7I2V3F7|A0A7I2V3F7_HUMAN,tr|A0A7I2YQQ5|A0A7I2YQQ5_HUMAN,tr|D6RCD7|D6RCD7_HUMAN" 8 1692.7632 2.38 117532 13766 3 1692.762913 565.2617 "Stress-70 protein, mitochondrial OS=Homo sapiens OX=9606 GN=HSPA9 PE=1 SV=2" 5.99 2502.1 - 339824 - - - -0.1908 - 3.219 0.519 - 546.2 1 2 0 -0.0003 14 0 0 0 1.41E+07 5.94E+06 - - - 7.4331 1 221125_WJC_METTL3_EV_vs_WT_F08.13771.13771.3 2.58E-09 18/92 R.GIASTSDPPTANIKPTPVVSTPSK.V sp|P12270|TPR_HUMAN 1 2364.2537 2.84 117535 13771 3 2364.25334 789.0918 Nucleoprotein TPR OS=Homo sapiens OX=9606 GN=TPR PE=1 SV=3 8.59 2502.8 - 1.56E+06 - - - -0.1337 - 3.509 0.583 - 217.3 1 2 0 -0.0003 24 0 0 0 7.08E+07 2.49E+07 - - - 7.9554 1 221125_WJC_METTL3_EV_vs_WT_F08.13772.13772.3 0.000186 18/56 R.KAHEILPNLVC[160.03]C[160.03]SAK.N "sp|P50990|TCPQ_HUMAN,tr|H7C4C8|H7C4C8_HUMAN" 2 1738.8858 0.52 117536 13772 3 1738.889898 580.6359 T-complex protein 1 subunit theta OS=Homo sapiens OX=9606 GN=CCT8 PE=1 SV=4 8.06 2502.9 - 469006 - - - 2.3302 - 3.731 0.553 - 510.7 1 2 0 0.0041 15 0 0 0 5.29E+07 1.03E+08 - - - 8.14 0.9999 221125_WJC_METTL3_EV_vs_WT_F08.13774.13774.4 1.17E-07 16/84 R.KAHEILPNLVC[160.03]C[160.03]SAK.N "sp|P50990|TCPQ_HUMAN,tr|H7C4C8|H7C4C8_HUMAN" 2 1738.8858 0.57 117538 13774 4 1738.882866 435.7287 T-complex protein 1 subunit theta OS=Homo sapiens OX=9606 GN=CCT8 PE=1 SV=4 8.06 2503.2 - 353571 - - - -1.7137 - 2.665 0.424 - 223.3 1 2 0 -0.003 15 0 0 0 3.74E+07 6.58E+07 - - - 3.2664 0.9998 221125_WJC_METTL3_EV_vs_WT_F08.13783.13783.4 1.24E-07 15/90 R.GTFHDDRDDGVDYWAK.R "tr|H0YF63|H0YF63_HUMAN,tr|E9PK91|E9PK91_HUMAN" 2 1895.8075 2.38 117543 13783 4 1895.812423 474.9591 Bcl-2-associated transcription factor 1 (Fragment) OS=Homo sapiens OX=9606 GN=BCLAF1 PE=1 SV=1 4.28 2504.4 - 569243 - - - 2.6205 - 2.613 0.557 - 151.4 1 2 1 0.005 16 0 0 0 1.98E+07 8.32E+06 - - - 4.4111 1 221125_WJC_METTL3_EV_vs_WT_F08.13784.13784.3 1.61E-05 17/64 K.RVEAAQETVADYQQTIK.K "sp|Q14203|DCTN1_HUMAN,tr|A0A804CDA6|A0A804CDA6_HUMAN,tr|E7EX90|E7EX90_HUMAN,tr|A0A7P0Z4C3|A0A7P0Z4C3_HUMAN,tr|Q6AWB1|Q6AWB1_HUMAN" 5 1948.9854 3.55 117544 13784 3 1948.988672 650.6691 Dynactin subunit 1 OS=Homo sapiens OX=9606 GN=DCTN1 PE=1 SV=3 4.68 2504.5 - 518663 - - - 1.6686 - 3.655 0.517 - 474.4 1 2 0 0.0033 17 0 0 0 9.75E+06 2.74E+06 - - - 7.5775 0.9921 221125_WJC_METTL3_EV_vs_WT_F08.13793.13793.2 1.68E-07 22-Dec R.R[166.11]AEQDSTTVAAF.A "sp|Q86U44|MTA70_HUMAN,tr|F5H6D8|F5H6D8_HUMAN,tr|H0YFV6|H0YFV6_HUMAN,tr|B4DTN4|B4DTN4_HUMAN" 4 1304.6236 0.03 117549 13793 2 1304.624488 653.3191 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 4.37 2505.6 - 1.23E+06 - - - 0.6699 - 2.263 0.51 - 450.4 1 1 0 0.0009 12 0 0 0 1.07E+06 3.59E+07 - - - 4.9564 0.9986 221125_WJC_METTL3_EV_vs_WT_F08.13795.13795.4 0.000529 15/96 R.QQTDMAVNWAGGLHHAK[136.11].K "sp|Q92769|HDAC2_HUMAN,tr|H3BM24|H3BM24_HUMAN" 2 1870.8988 1.72 117551 13795 4 1870.906154 468.732 Histone deacetylase 2 OS=Homo sapiens OX=9606 GN=HDAC2 PE=1 SV=2 6.92 2505.8 - 1.10E+06 - - - 3.9307 - 2.332 0.372 - 158.5 1 2 0 0.0074 17 0 0 0 6.46E+07 3.76E+07 - - - 2.7558 0.9998 221125_WJC_METTL3_EV_vs_WT_F08.13797.13797.4 0.000538 Nov-90 R.GTFHDDR[166.11]DDGVDYWAK[136.11].R "tr|H0YF63|H0YF63_HUMAN,tr|E9PK91|E9PK91_HUMAN" 2 1913.8299 2.38 117553 13797 4 1913.829376 479.4648 Bcl-2-associated transcription factor 1 (Fragment) OS=Homo sapiens OX=9606 GN=BCLAF1 PE=1 SV=1 4.28 2506.1 - 507090 - - - -0.2869 - 2.24 0.494 - 85.9 1 2 1 -0.0005 16 0 0 0 1.98E+07 8.32E+06 - - - 3.8097 0.9999 221125_WJC_METTL3_EV_vs_WT_F08.13800.13800.3 2.13E-07 16/72 K.NKPQVPVPGSDISETQVER.K sp|Q96BK5|PINX1_HUMAN 1 2079.0596 1.46 117556 13800 3 2079.066229 694.0272 PIN2\TERF1-interacting telomerase inhibitor 1 OS=Homo sapiens OX=9606 GN=PINX1 PE=1 SV=2 4.68 2506.5 - 288163 - - - 3.1659 - 3.087 0.566 - 276.2 1 2 0 0.0066 19 0 0 0 1.20E+07 8.24E+06 - - - 7.6178 1 221125_WJC_METTL3_EV_vs_WT_F08.13803.13803.4 1.66E-07 17/96 R.QQTDMAVNWAGGLHHAK.K "sp|Q92769|HDAC2_HUMAN,tr|H3BM24|H3BM24_HUMAN" 2 1862.8846 1.73 117557 13803 4 1862.884092 466.7284 Histone deacetylase 2 OS=Homo sapiens OX=9606 GN=HDAC2 PE=1 SV=2 6.92 2506.9 - 2.54E+06 - - - -0.2727 - 3.011 0.544 - 252.2 1 2 0 -0.0005 17 0 0 0 6.56E+07 3.80E+07 - - - 4.3435 1 221125_WJC_METTL3_EV_vs_WT_F08.13804.13804.3 1.45E-10 21/68 R.DQMEGSPNSSESFEHIAR[166.11].S "sp|Q9Y520|PRC2C_HUMAN,tr|E7EPN9|E7EPN9_HUMAN" 2 2029.8675 0.97 117558 13804 3 2029.864609 677.6298 Protein PRRC2C OS=Homo sapiens OX=9606 GN=PRRC2C PE=1 SV=4 4.4 2507 - 1.31E+06 - - - -1.4257 - 3.373 0.692 - 476.9 1 2 0 -0.0029 18 0 0 0 5.72E+07 5.88E+07 - - - 9.2818 1 221125_WJC_METTL3_EV_vs_WT_F08.13805.13805.3 2.85E-07 17/76 K.STTPPPAEPVSLPQEPPKPR.V tr|A0A7I2V647|A0A7I2V647_HUMAN 1 2124.1215 3.31 117559 13805 3 2124.122966 709.0478 Ras GTPase-activating protein-binding protein 2 OS=Homo sapiens OX=9606 GN=G3BP2 PE=1 SV=1 5.86 2507.1 - 749812 - - - 0.6812 - 3.34 0.515 - 293.8 1 2 0 0.0014 20 0 0 0 4.56E+07 1.38E+07 - - - 7.2071 0.9891 221125_WJC_METTL3_EV_vs_WT_F08.13806.13806.3 1.07E-05 Oct-80 Y.SFASQQQK[136.11]PEDTTIPSTELAK[136.11].Q "sp|P48556|PSMD8_HUMAN,tr|R4GMR5|R4GMR5_HUMAN" 2 2321.1722 0.78 117560 13806 3 2321.176957 774.7313 26S proteasome non-ATPase regulatory subunit 8 OS=Homo sapiens OX=9606 GN=PSMD8 PE=1 SV=2 4.68 2507.2 - 332346 - - - 2.0619 - 2.026 0.505 - 64.5 1 1 0 0.0048 21 0 0 0 6.12E+06 7.83E+06 - - - 5.8617 1 221125_WJC_METTL3_EV_vs_WT_F08.13810.13810.3 2.91E-07 18/68 K.ANELPQPPVPEPANAGK[136.11]R[166.11].K "sp|P78347|GTF2I_HUMAN,tr|A0A494C1K3|A0A494C1K3_HUMAN" 2 1902.0078 1.85 117562 13810 3 1902.005726 635.0099 General transcription factor II-I OS=Homo sapiens OX=9606 GN=GTF2I PE=1 SV=2 6.19 2507.8 - 4.99E+06 - - - -1.1062 - 2.779 0.498 - 298.5 1 2 0 -0.0021 18 0 0 0 3.62E+08 1.96E+08 - - - 6.6367 0.9996 221125_WJC_METTL3_EV_vs_WT_F08.13816.13816.4 0.000942 Aug-66 R.K[136.11]EDWNEIDPIK[136.11]K[136.11].K sp|Q10471|GALT2_HUMAN 1 1537.8203 0.04 117568 13816 4 1537.81883 385.4623 Polypeptide N-acetylgalactosaminyltransferase 2 OS=Homo sapiens OX=9606 GN=GALNT2 PE=1 SV=1 4.78 2508.4 - 291236 - - - -0.9292 - 1.42 0.358 - 38.7 1 2 0 -0.0014 12 0 0 0 1.51E+05 4.18E+06 - - - 2.4743 1 221125_WJC_METTL3_EV_vs_WT_F08.13823.13823.4 4.67E-07 14/108 R.C[160.03]ATPNISPATSVVQHSHLR[166.11].E sp|Q9Y597|KCTD3_HUMAN 1 2084.0461 0.48 117572 13823 4 2084.044948 522.0188 BTB\POZ domain-containing protein KCTD3 OS=Homo sapiens OX=9606 GN=KCTD3 PE=1 SV=2 8.27 2509.2 - 502989 - - - -0.5417 - 2.819 0.492 - 89 1 2 0 -0.0011 19 0 0 0 4.68E+06 9.69E+06 - - - 3.8586 1 221125_WJC_METTL3_EV_vs_WT_F08.13828.13828.3 4.66E-10 17/68 R.DQMEGSPNSSESFEHIAR.S "sp|Q9Y520|PRC2C_HUMAN,tr|E7EPN9|E7EPN9_HUMAN" 2 2019.8592 0.97 117575 13828 3 2019.85981 674.2937 Protein PRRC2C OS=Homo sapiens OX=9606 GN=PRRC2C PE=1 SV=4 4.4 2509.9 - 686742 - - - 0.2857 - 3.367 0.596 - 285.9 1 2 0 0.0006 18 0 0 0 5.71E+07 5.88E+07 - - - 8.2077 1 221125_WJC_METTL3_EV_vs_WT_F08.13830.13830.4 7.99E-09 24/114 K.MHDLNTDQENLVGTHDAPIR[166.11].C "sp|O43684|BUB3_HUMAN,tr|J3QT28|J3QT28_HUMAN,tr|J3QSX4|J3QSX4_HUMAN" 3 2285.0734 0.61 117577 13830 4 2285.071154 572.2756 Mitotic checkpoint protein BUB3 OS=Homo sapiens OX=9606 GN=BUB3 PE=1 SV=1 4.63 2510.1 - 1.34E+06 - - - -0.9886 - 3.829 0.6 - 542.6 1 2 0 -0.0023 20 0 0 0 3.73E+07 6.11E+07 - - - 4.8966 1 221125_WJC_METTL3_EV_vs_WT_F08.13832.13832.3 7.65E-07 15/56 R.STSHK[136.11]PDEIYGMIER[166.11].L sp|Q86U44|MTA70_HUMAN 1 1779.8581 0.08 117579 13832 3 1779.85634 594.2933 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 5.42 2510.3 - 400696 - - - -0.963 - 2.766 0.551 - 248.9 1 2 0 -0.0017 15 0 0 0 9.34E+05 1.17E+07 - - - 7.3374 0.9999 221125_WJC_METTL3_EV_vs_WT_F08.13837.13837.4 1.16E-08 23/120 R.ILDDSKDSVGDSLSGKEDLGR.K "sp|Q8IWI9|MGAP_HUMAN,tr|H3BP52|H3BP52_HUMAN" 2 2205.0761 1.28 117582 13837 4 2205.07458 552.2763 MAX gene-associated protein OS=Homo sapiens OX=9606 GN=MGA PE=1 SV=4 4.17 2511 - 765580 - - - -0.6825 - 4.473 0.598 - 422.1 1 2 2 -0.0015 21 0 0 0 1.21E+07 9.43E+06 - - - 4.9259 0.9797 221125_WJC_METTL3_EV_vs_WT_F08.13839.13839.3 7.59E-05 Sep-60 K.KQSKPVTTPEEIAQVA.T "sp|P10809|CH60_HUMAN,tr|A0A7I2V599|A0A7I2V599_HUMAN,tr|E7EXB4|E7EXB4_HUMAN,tr|A0A7I2YQ71|A0A7I2YQ71_HUMAN,tr|E7ESH4|E7ESH4_HUMAN,tr|A0A7I2V5M1|A0A7I2V5M1_HUMAN,tr|A0A7I2V5K3|A0A7I2V5K3_HUMAN,tr|A0A7I2V369|A0A7I2V369_HUMAN" 8 1724.9309 1.66 117584 13839 3 1724.929677 575.9842 "60 kDa heat shock protein, mitochondrial OS=Homo sapiens OX=9606 GN=HSPD1 PE=1 SV=2" 6.14 2511.2 - 571884 - - - -0.6887 - 2.193 0.361 - 82 1 1 0 -0.0012 16 0 0 0 3.30E+07 1.98E+07 - - - 4.5794 1 221125_WJC_METTL3_EV_vs_WT_F08.13842.13842.2 1.03E-15 15/46 R.TQSSASLAASYAAQQHPQAAASYR[166.11].G sp|Q96PK6|RBM14_HUMAN 1 2474.1814 2.23 117587 13842 2 2474.173187 1238.098 RNA-binding protein 14 OS=Homo sapiens OX=9606 GN=RBM14 PE=1 SV=2 8.29 2511.6 - 279204 - - - -3.313 - 3.651 0.732 - 304.1 1 2 0 -0.0082 24 0 0 0 2.69E+07 1.20E+07 - - - 7.6288 0.9988 221125_WJC_METTL3_EV_vs_WT_F08.13847.13847.4 0.000609 14/78 R.QRPSEIKDYSPYFK.T sp|P08779|K1C16_HUMAN 1 1756.8784 151.01 117590 13847 4 1756.87455 440.2269 "Keratin, type I cytoskeletal 16 OS=Homo sapiens OX=9606 GN=KRT16 PE=1 SV=4" 8.43 2512.2 - 2.75E+06 - - - -2.2113 - 2.456 0.383 - 187.2 1 2 1 -0.0039 14 0 0 0 1.14E+09 7.53E+06 - - - 2.8856 0.9999 221125_WJC_METTL3_EV_vs_WT_F08.13849.13849.3 9.60E-07 Dec-56 M.PGHLQEGFGC[160.03]VVTNR[166.11].F sp|Q8NC51|PAIRB_HUMAN 1 1679.8077 0.51 117592 13849 3 1679.811549 560.9432 Plasminogen activator inhibitor 1 RNA-binding protein OS=Homo sapiens OX=9606 GN=SERBP1 PE=1 SV=2 7.13 2512.5 - 346785 - - - 2.2651 - 2.497 0.512 - 170.1 1 2 0 0.0038 15 0 0 0 3.10E+06 6.10E+06 - - - 6.635 1 221125_WJC_METTL3_EV_vs_WT_F08.13852.13852.3 1.66E-09 18/56 R.K[136.11]AHEILPNLVC[160.03]C[160.03]SAK[136.11].N "sp|P50990|TCPQ_HUMAN,tr|H7C4C8|H7C4C8_HUMAN" 2 1754.9142 0.51 117593 13852 3 1754.911844 585.9787 T-complex protein 1 subunit theta OS=Homo sapiens OX=9606 GN=CCT8 PE=1 SV=4 8.06 2512.9 - 2.67E+06 - - - -1.3687 - 3.333 0.607 - 480.9 1 2 0 -0.0024 15 0 0 0 5.27E+07 1.03E+08 - - - 8.4481 0.9997 221125_WJC_METTL3_EV_vs_WT_F08.13855.13855.3 4.83E-05 Oct-72 R.AIGSASEGAQSSLQEVYHK[136.11].S sp|P28066|PSA5_HUMAN 1 1968.9632 0.75 117596 13855 3 1968.957138 657.3284 Proteasome subunit alpha type-5 OS=Homo sapiens OX=9606 GN=PSMA5 PE=1 SV=3 5.4 2513.2 - 429808 - - - -3.096 - 2.133 0.458 - 74.1 1 2 0 -0.0061 19 0 0 0 6.00E+06 8.04E+06 - - - 5.5057 1 221125_WJC_METTL3_EV_vs_WT_F08.13859.13859.2 4.42E-13 28/46 R.TQSSASLAASYAAQQHPQAAASYR.G sp|Q96PK6|RBM14_HUMAN 1 2464.1731 2.23 117598 13859 2 2464.170572 1233.0938 RNA-binding protein 14 OS=Homo sapiens OX=9606 GN=RBM14 PE=1 SV=2 8.29 2513.7 - 855998 - - - -1.0316 - 5.155 0.718 - 1420.7 1 2 0 -0.0025 24 0 0 0 2.69E+07 1.20E+07 - - - 8.3753 0.9999 221125_WJC_METTL3_EV_vs_WT_F08.13860.13860.3 2.62E-07 14/68 K.LQIASDENYKDPTNLQGK.L "sp|Q13813|SPTN1_HUMAN,tr|A0A0D9SFF6|A0A0D9SFF6_HUMAN,tr|A0A0D9SF54|A0A0D9SF54_HUMAN,tr|A0A0D9SGF6|A0A0D9SGF6_HUMAN" 4 2033.0065 1.46 117599 13860 3 2033.006484 678.6761 "Spectrin alpha chain, non-erythrocytic 1 OS=Homo sapiens OX=9606 GN=SPTAN1 PE=1 SV=3" 4.56 2513.9 - 976343 - - - -0.032 - 2.975 0.543 - 191.8 1 2 1 -0.0001 18 0 0 0 3.98E+07 2.73E+07 - - - 7.3087 0.9998 221125_WJC_METTL3_EV_vs_WT_F08.13863.13863.4 4.09E-06 17/90 K.SGKWEGLVYAPPGKEK.Q "sp|Q9Y2W1|TR150_HUMAN,tr|A0A3B3ITZ9|A0A3B3ITZ9_HUMAN" 2 1744.9148 2.2 117602 13863 4 1744.912023 437.236 Thyroid hormone receptor-associated protein 3 OS=Homo sapiens OX=9606 GN=THRAP3 PE=1 SV=2 8.16 2514.2 - 704783 - - - -1.6035 - 2.681 0.484 - 182.5 1 2 2 -0.0028 16 0 0 0 5.79E+07 2.63E+07 - - - 3.7854 0.9023 221125_WJC_METTL3_EV_vs_WT_F08.13866.13866.2 0.000744 26-Sep R.R[166.11]AEQDSTTVAAFAS.S "sp|Q86U44|MTA70_HUMAN,tr|F5H6D8|F5H6D8_HUMAN,tr|H0YFV6|H0YFV6_HUMAN,tr|B4DTN4|B4DTN4_HUMAN" 4 1462.6928 0.04 117603 13866 2 1462.696068 732.3537 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 4.37 2514.6 - 594299 - - - 2.2643 - 1.508 0.364 - 147.2 1 1 0 0.0033 14 0 0 0 8.41E+05 1.87E+07 - - - 2.7593 0.9998 221125_WJC_METTL3_EV_vs_WT_F08.13870.13870.3 3.76E-08 16/68 K.LQIASDENYK[136.11]DPTNLQGK[136.11].L "sp|Q13813|SPTN1_HUMAN,tr|A0A0D9SFF6|A0A0D9SFF6_HUMAN,tr|A0A0D9SF54|A0A0D9SF54_HUMAN,tr|A0A0D9SGF6|A0A0D9SGF6_HUMAN" 4 2049.0349 1.46 117606 13870 3 2049.029063 684.0189 "Spectrin alpha chain, non-erythrocytic 1 OS=Homo sapiens OX=9606 GN=SPTAN1 PE=1 SV=3" 4.56 2515 - 1.05E+06 - - - -2.8726 - 3.19 0.59 - 272.7 1 2 1 -0.0059 18 0 0 0 3.98E+07 2.73E+07 - - - 8.0049 0.9998 221125_WJC_METTL3_EV_vs_WT_F08.13876.13876.3 1.03E-05 16/60 K.SGKWEGLVYAPPGKEK.Q "sp|Q9Y2W1|TR150_HUMAN,tr|A0A3B3ITZ9|A0A3B3ITZ9_HUMAN" 2 1744.9148 2.57 117609 13876 3 1744.913842 582.6456 Thyroid hormone receptor-associated protein 3 OS=Homo sapiens OX=9606 GN=THRAP3 PE=1 SV=2 8.16 2515.7 - 1.02E+06 - - - -0.5611 - 2.574 0.458 - 285.8 1 2 2 -0.001 16 0 0 0 3.91E+07 1.52E+07 - - - 6.0719 1 221125_WJC_METTL3_EV_vs_WT_F08.13881.13881.3 1.75E-07 15/40 R.LVNHFVEEFK[136.11]R[166.11].K "sp|P0DMV8|HS71A_HUMAN,sp|P0DMV9|HS71B_HUMAN,tr|V9GZ37|V9GZ37_HUMAN,tr|A0A0G2JIW1|A0A0G2JIW1_HUMAN" 4 1434.7739 0.22 117612 13881 3 1434.772247 479.2652 Heat shock 70 kDa protein 1A OS=Homo sapiens OX=9606 GN=HSPA1A PE=1 SV=1 6.76 2516.4 - 1.05E+06 - - - -1.12 - 2.77 0.544 - 478.1 1 2 0 -0.0016 11 0 0 0 3.33E+07 1.51E+08 - - - 7.499 0.9999 221125_WJC_METTL3_EV_vs_WT_F08.13884.13884.4 1.58E-07 23/108 R.LRGIEQAVQSHAVAEEEAR.K "sp|Q16891|MIC60_HUMAN,tr|B9A067|B9A067_HUMAN,tr|C9J406|C9J406_HUMAN,tr|H7C463|H7C463_HUMAN" 4 2092.0661 1.37 117615 13884 4 2092.0653 524.0238 MICOS complex subunit MIC60 OS=Homo sapiens OX=9606 GN=IMMT PE=1 SV=1 4.91 2516.6 - 879239 - - - -0.3967 - 4.196 0.554 - 623.9 1 2 1 -0.0008 19 0 0 0 2.49E+07 1.82E+07 - - - 4.5329 0.9999 221125_WJC_METTL3_EV_vs_WT_F08.13888.13888.3 8.21E-06 16/68 K.ALEEDIENHATDVHQAVK.L "tr|H3BQK9|H3BQK9_HUMAN,tr|H3BPE1|H3BPE1_HUMAN,tr|A0A590UJG2|A0A590UJG2_HUMAN,tr|A0A0A6YYJ5|A0A0A6YYJ5_HUMAN" 4 2017.9705 0.4 117616 13888 3 2017.966727 673.6641 "Microtubule-actin cross-linking factor 1, isoforms 1\2\3\5 OS=Homo sapiens OX=9606 GN=MACF1 PE=1 SV=1" 4.49 2517.1 - 651923 - - - -1.8687 - 2.56 0.47 - 199.2 1 2 0 -0.0038 18 0 0 0 1.98E+07 4.95E+07 - - - 6.1197 0.9997 221125_WJC_METTL3_EV_vs_WT_F08.13891.13891.4 4.36E-07 16/90 K.SGK[136.11]WEGLVYAPPGK[136.11]EK[136.11].Q "sp|Q9Y2W1|TR150_HUMAN,tr|A0A3B3ITZ9|A0A3B3ITZ9_HUMAN" 2 1768.9574 2.61 117618 13891 4 1768.956123 443.2466 Thyroid hormone receptor-associated protein 3 OS=Homo sapiens OX=9606 GN=THRAP3 PE=1 SV=2 8.16 2517.5 - 712618 - - - -0.7338 - 2.535 0.43 - 165.8 1 2 2 -0.0013 16 0 0 0 7.05E+07 2.70E+07 - - - 3.296 0.9997 221125_WJC_METTL3_EV_vs_WT_F08.13893.13893.4 9.54E-06 14/84 K.GVIVDK[136.11]DFSHPQMPK[136.11].K "sp|P48643|TCPE_HUMAN,tr|E9PCA1|E9PCA1_HUMAN,tr|B7ZAR1|B7ZAR1_HUMAN,tr|E7ENZ3|E7ENZ3_HUMAN" 4 1712.8891 0.63 117620 13893 4 1712.887845 429.2295 T-complex protein 1 subunit epsilon OS=Homo sapiens OX=9606 GN=CCT5 PE=1 SV=1 6.75 2517.6 - 1.50E+06 - - - -0.7193 - 2.541 0.446 - 93.8 1 2 1 -0.0012 15 0 0 0 4.87E+07 7.78E+07 - - - 3.4413 0.9998 221125_WJC_METTL3_EV_vs_WT_F08.13895.13895.3 1.80E-05 15/56 K.GVIVDKDFSHPQMPK.K "sp|P48643|TCPE_HUMAN,tr|E9PCA1|E9PCA1_HUMAN,tr|B7ZAR1|B7ZAR1_HUMAN,tr|E7ENZ3|E7ENZ3_HUMAN" 4 1696.8607 0.64 117622 13895 3 1696.860304 566.6275 T-complex protein 1 subunit epsilon OS=Homo sapiens OX=9606 GN=CCT5 PE=1 SV=1 6.75 2517.9 - 462901 - - - -0.2198 - 2.567 0.441 - 202.6 1 2 1 -0.0004 15 0 0 0 3.32E+07 5.18E+07 - - - 5.9166 0.9874 221125_WJC_METTL3_EV_vs_WT_F08.13899.13899.3 0.233 Nov-60 K.EFKEHIAASVSIPSEK.Q "sp|P46379|BAG6_HUMAN,tr|F6UR09|F6UR09_HUMAN,tr|A0A7I2V508|A0A7I2V508_HUMAN,tr|F6U1F2|F6U1F2_HUMAN,tr|F6U341|F6U341_HUMAN,tr|F6WML8|F6WML8_HUMAN,tr|A0A0G2JJM1|A0A0G2JJM1_HUMAN,tr|X6REW1|X6REW1_HUMAN,tr|A0A7I2V3H1|A0A7I2V3H1_HUMAN,tr|A0A7P0MQS5|A0A7P0MQS5_HUMAN,tr|F6XTU0|F6XTU0_HUMAN,tr|F6X9W3|F6X9W3_HUMAN,tr|F6VEM6|F6VEM6_HUMAN,tr|A0A0G2JJR8|A0A0G2JJR8_HUMAN,tr|F6S6P2|F6S6P2_HUMAN,tr|F6TC96|F6TC96_HUMAN,tr|A0A0G2JL47|A0A0G2JL47_HUMAN,tr|A0A024RCR6|A0A024RCR6_HUMAN,tr|A0A0G2JK23|A0A0G2JK23_HUMAN,tr|A0A1B0GX79|A0A1B0GX79_HUMAN" 20 1770.9152 2.71 117624 13899 3 1770.916431 591.3123 Large proline-rich protein BAG6 OS=Homo sapiens OX=9606 GN=BAG6 PE=1 SV=2 5.5 2518.4 - 1.17E+06 - - - 0.6867 - 1.695 0.244 - 95.3 1 2 1 0.0012 16 0 0 0 2.07E+07 7.62E+06 - - - 2.614 0.9847 221125_WJC_METTL3_EV_vs_WT_F08.13902.13902.2 4.98E-05 Nov-46 R.SDSPVPTAPTSGGPK[136.11]PSTASAVPE.L "sp|Q86U44|MTA70_HUMAN,tr|B4E349|B4E349_HUMAN,tr|F5H6D8|F5H6D8_HUMAN,tr|B4DTN4|B4DTN4_HUMAN" 4 2244.1001 0.01 117627 13902 2 2244.099048 1123.0573 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 4.75 2518.7 - 580750 - - - -0.4786 - 1.709 0.463 - 123.5 1 1 0 -0.0011 24 0 0 0 6.01E+05 6.52E+07 - - - 3.7779 1 221125_WJC_METTL3_EV_vs_WT_F08.13903.13903.3 3.73E-10 20/88 K.RPGGSSPLNAVPC[160.03]EGPPGSEPPR.R sp|P48634|PRC2A_HUMAN 1 2314.1124 3.5 117628 13903 3 2314.111652 772.3781 Protein PRRC2A OS=Homo sapiens OX=9606 GN=PRRC2A PE=1 SV=3 6.14 2518.9 - 572862 - - - -0.3353 - 4.15 0.635 - 366.2 1 2 0 -0.0008 23 0 0 0 1.09E+07 3.12E+06 - - - 8.9579 0.9995 221125_WJC_METTL3_EV_vs_WT_F08.13908.13908.3 0.00118 15/52 R.NALQQENHIIDGVK[136.11].V "sp|Q9GZT3|SLIRP_HUMAN,tr|H0YJW7|H0YJW7_HUMAN,tr|A0A087WUN7|A0A087WUN7_HUMAN,tr|G3V2S9|G3V2S9_HUMAN,tr|H0YJ40|H0YJ40_HUMAN,tr|G3V4X6|G3V4X6_HUMAN" 6 1585.8304 1.23 117631 13908 3 1585.830058 529.6174 "SRA stem-loop-interacting RNA-binding protein, mitochondrial OS=Homo sapiens OX=9606 GN=SLIRP PE=1 SV=1" 5.32 2519.5 - 839329 - - - -0.1961 - 2.047 0.307 - 258.7 1 2 0 -0.0003 14 0 0 0 1.76E+07 1.43E+07 - - - 3.8665 1 221125_WJC_METTL3_EV_vs_WT_F08.13910.13910.4 6.02E-08 19/102 K.ALEEDIENHATDVHQAVK.L "tr|H3BQK9|H3BQK9_HUMAN,tr|H3BPE1|H3BPE1_HUMAN,tr|A0A590UJG2|A0A590UJG2_HUMAN,tr|A0A0A6YYJ5|A0A0A6YYJ5_HUMAN" 4 2017.9705 3.63 117633 13910 4 2017.971397 505.4999 "Microtubule-actin cross-linking factor 1, isoforms 1\2\3\5 OS=Homo sapiens OX=9606 GN=MACF1 PE=1 SV=1" 4.49 2519.6 - 1.84E+06 - - - 0.4455 - 3.549 0.586 - 237.7 1 2 0 0.0009 18 0 0 0 2.83E+07 7.82E+06 - - - 4.7602 1 221125_WJC_METTL3_EV_vs_WT_F08.13913.13913.2 2.37E-05 15/26 R.QRPSEIKDYSPYFK.T sp|P08779|K1C16_HUMAN 1 1756.8784 999 117636 13913 2 1756.881813 879.4465 "Keratin, type I cytoskeletal 16 OS=Homo sapiens OX=9606 GN=KRT16 PE=1 SV=4" 8.43 2520 - 422394 - - - 1.9227 - 2.966 0.578 - 518.1 1 2 1 0.0034 14 0 0 0 2.09E+07 0.00E+00 - - - 6.0374 0.9999 221125_WJC_METTL3_EV_vs_WT_F08.13917.13917.3 3.27E-09 19/56 K.GVIVDK[136.11]DFSHPQMPK[136.11].K "sp|P48643|TCPE_HUMAN,tr|E9PCA1|E9PCA1_HUMAN,tr|B7ZAR1|B7ZAR1_HUMAN,tr|E7ENZ3|E7ENZ3_HUMAN" 4 1712.8891 0.64 117638 13917 3 1712.885543 571.9703 T-complex protein 1 subunit epsilon OS=Homo sapiens OX=9606 GN=CCT5 PE=1 SV=1 6.75 2520.5 - 1.27E+06 - - - -2.0632 - 3.546 0.572 - 423.1 1 2 1 -0.0035 15 0 0 0 3.32E+07 5.18E+07 - - - 8.2192 0.9988 221125_WJC_METTL3_EV_vs_WT_F08.13920.13920.4 0.00171 Dec-84 R.STSHK[136.11]PDEIYGMIER[166.11].L sp|Q86U44|MTA70_HUMAN 1 1779.8581 0.05 117641 13920 4 1779.849464 445.9718 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 5.42 2520.9 - 416497 - - - -4.8262 - 1.68 0.432 - 72.6 1 2 0 -0.0086 15 0 0 0 7.96E+05 1.54E+07 - - - 3.1694 1 221125_WJC_METTL3_EV_vs_WT_F08.13925.13925.3 2.15E-10 21/84 R.LLEGEDAHLSSSQFSSGSQSSR.D sp|P02533|K1C14_HUMAN 1 2308.0567 999 117644 13925 3 2308.054681 770.3595 "Keratin, type I cytoskeletal 14 OS=Homo sapiens OX=9606 GN=KRT14 PE=1 SV=4" 4.65 2521.4 - 4.14E+06 - - - -0.8951 - 3.923 0.736 - 396.2 1 2 0 -0.0021 22 0 0 0 8.40E+09 0.00E+00 - - - 9.9857 0.9993 221125_WJC_METTL3_EV_vs_WT_F08.13926.13926.3 0.00228 14/48 K.SVEEGKIDGIIDK.T sp|Q96A49|SYAP1_HUMAN 1 1401.7351 1.34 117645 13926 3 1401.734039 468.2523 Synapse-associated protein 1 OS=Homo sapiens OX=9606 GN=SYAP1 PE=1 SV=1 4.32 2521.6 - 924724 - - - -0.7748 - 2.225 0.366 - 164.4 1 2 1 -0.0011 13 0 0 0 2.27E+07 1.69E+07 - - - 4.7886 1 221125_WJC_METTL3_EV_vs_WT_F08.13928.13928.3 1.41E-07 16/60 R.LAQMISDHNDADFEEK.V "sp|Q14157|UBP2L_HUMAN,tr|Q5VU78|Q5VU78_HUMAN,tr|F8W726|F8W726_HUMAN,tr|Q5VU81|Q5VU81_HUMAN,tr|Q5VU79|Q5VU79_HUMAN,tr|Q5VU80|Q5VU80_HUMAN,tr|Q5VU77|Q5VU77_HUMAN" 7 1861.8152 10.01 117647 13928 3 1861.809759 621.6124 Ubiquitin-associated protein 2-like OS=Homo sapiens OX=9606 GN=UBAP2L PE=1 SV=2 4.1 2521.8 - 418915 - - - -2.9455 - 3.289 0.66 - 311.6 1 2 0 -0.0055 16 0 0 0 6.73E+06 6.73E+05 - - - 8.9517 0.9999 221125_WJC_METTL3_EV_vs_WT_F08.13929.13929.3 0.000333 10/112 R.ATGPEAAGGGGAGGGGGGYR[166.11]PIIQSPGYK[136.11].T sp|Q9ULL5|PRR12_HUMAN 1 2577.2691 2.6 117648 13929 3 2577.268728 860.097 Proline-rich protein 12 OS=Homo sapiens OX=9606 GN=PRR12 PE=1 SV=3 8.54 2521.9 - 349792 - - - -0.1377 - 2.142 0.433 - 49.5 1 2 0 -0.0004 29 0 0 0 1.13E+07 4.34E+06 - - - 5.1199 0.9993 221125_WJC_METTL3_EV_vs_WT_F08.13933.13933.4 0.000566 19/90 K.TLTTVQGIADDYDK[136.11]K[136.11]K[136.11].L "sp|P41567|EIF1_HUMAN,sp|O60739|EIF1B_HUMAN,tr|K7EM18|K7EM18_HUMAN" 3 1818.9789 0.88 117650 13933 4 1818.977072 455.752 Eukaryotic translation initiation factor 1 OS=Homo sapiens OX=9606 GN=EIF1 PE=1 SV=1 5.71 2522.5 - 1.78E+06 - - - -1.0291 - 3.25 0.374 - 279 1 2 1 -0.0019 16 0 0 0 7.01E+07 7.97E+07 - - - 2.896 1 221125_WJC_METTL3_EV_vs_WT_F08.13935.13935.3 1.22E-06 15/76 K.SSSATASQPPESLPQPGLQK.S sp|Q5JSZ5|PRC2B_HUMAN 1 2009.0065 2.09 117652 13935 3 2009.00673 670.6761 Protein PRRC2B OS=Homo sapiens OX=9606 GN=PRRC2B PE=1 SV=2 5.72 2522.7 - 931947 - - - 0.0901 - 2.774 0.586 - 150.9 1 2 0 0.0002 20 0 0 0 7.18E+07 3.44E+07 - - - 7.5485 1 221125_WJC_METTL3_EV_vs_WT_F08.13937.13937.2 2.37E-13 13/40 Q.SSSASYGGGFGGGSC[160.03]QLGGGR.G "sp|P13646|K1C13_HUMAN,tr|K7EMJ2|K7EMJ2_HUMAN,tr|K7ERE3|K7ERE3_HUMAN,tr|K7EQH6|K7EQH6_HUMAN" 4 1904.8071 8.83 117654 13937 2 1904.804491 953.4108 "Keratin, type I cytoskeletal 13 OS=Homo sapiens OX=9606 GN=KRT13 PE=1 SV=4" 7.94 2523 - 417852 - - - -1.3896 - 3.089 0.746 - 337.5 1 1 0 -0.0026 21 0 0 0 4.53E+06 5.13E+05 - - - 7.323 1 221125_WJC_METTL3_EV_vs_WT_F08.13945.13945.3 2.95E-13 24/72 K.THSVNGITEEADPTIYSGK[136.11].V "sp|O75534|CSDE1_HUMAN,tr|E9PLT0|E9PLT0_HUMAN" 2 2025.9735 0.53 117660 13945 3 2025.97182 676.3318 Cold shock domain-containing protein E1 OS=Homo sapiens OX=9606 GN=CSDE1 PE=1 SV=2 4.65 2523.8 - 1.35E+06 - - - -0.812 - 4.323 0.654 - 779.4 1 2 0 -0.0016 19 0 0 0 3.73E+07 7.07E+07 - - - 9.4276 0.9999 221125_WJC_METTL3_EV_vs_WT_F08.13947.13947.4 1.15E-05 15/102 R.SQESGYYDR[166.11]MDYEDDR[166.11]LR[166.11].D "sp|P43243|MATR3_HUMAN,tr|A8MXP9|A8MXP9_HUMAN,tr|D6R991|D6R991_HUMAN,tr|A0A0R4J2E8|A0A0R4J2E8_HUMAN,tr|D6REM6|D6REM6_HUMAN" 5 2326.9903 0.08 117662 13947 4 2326.990254 582.7549 Matrin-3 OS=Homo sapiens OX=9606 GN=MATR3 PE=1 SV=2 4.23 2524.1 - 943507 - - - -0.0193 - 2.027 0.533 - 146.4 1 2 2 0 18 0 0 0 5.85E+05 7.49E+06 - - - 4.1073 1 221125_WJC_METTL3_EV_vs_WT_F08.13948.13948.3 5.86E-08 18/112 R.ATGPEAAGGGGAGGGGGGYRPIIQSPGYK.T sp|Q9ULL5|PRR12_HUMAN 1 2559.2466 2.6 117663 13948 3 2559.244176 854.0895 Proline-rich protein 12 OS=Homo sapiens OX=9606 GN=PRR12 PE=1 SV=3 8.54 2524.2 - 904896 - - - -0.9522 - 2.773 0.553 - 208.7 1 2 0 -0.0024 29 0 0 0 1.13E+07 4.34E+06 - - - 7.0512 1 221125_WJC_METTL3_EV_vs_WT_F08.13949.13949.2 1.39E-14 25/42 R.LLEGEDAHLSSSQFSSGSQSSR.D sp|P02533|K1C14_HUMAN 1 2308.0567 999 117664 13949 2 2308.055243 1155.0356 "Keratin, type I cytoskeletal 14 OS=Homo sapiens OX=9606 GN=KRT14 PE=1 SV=4" 4.65 2524.3 - 622312 - - - -0.6516 - 4.512 0.769 - 1138 1 2 0 -0.0015 22 0 0 0 1.59E+08 0.00E+00 - - - 8.4248 0.9195 221125_WJC_METTL3_EV_vs_WT_F08.13950.13950.4 0.00619 10/102 G.LLQDDAHPTLVTYADHSK[136.11].L "sp|Q86U44|MTA70_HUMAN,tr|F5H6D8|F5H6D8_HUMAN,tr|H0YFV6|H0YFV6_HUMAN,tr|B4DTN4|B4DTN4_HUMAN" 4 2031.0153 0.33 117665 13950 4 2031.012591 508.7611 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 5.13 2524.4 - 253407 - - - -1.319 - 1.909 0.315 - 68.9 1 1 0 -0.0027 18 0 0 0 4.42E+05 1.34E+06 - - - 2.1885 1 221125_WJC_METTL3_EV_vs_WT_F08.13960.13960.3 1.69E-09 17/68 K.ANELPQPPVPEPANAGKR.K "sp|P78347|GTF2I_HUMAN,tr|A0A494C1K3|A0A494C1K3_HUMAN" 2 1883.9854 1.98 117672 13960 3 1883.982419 629.0024 General transcription factor II-I OS=Homo sapiens OX=9606 GN=GTF2I PE=1 SV=2 6.19 2525.5 - 1.40E+06 - - - -1.5611 - 2.95 0.57 - 250.1 1 2 0 -0.0029 18 0 0 0 2.42E+08 1.22E+08 - - - 7.5879 1 221125_WJC_METTL3_EV_vs_WT_F08.13963.13963.3 8.96E-09 17/84 R.SSVETTPSVIQHVGQPPATPAK.H "sp|Q6W2J9|BCOR_HUMAN,tr|H7BZ37|H7BZ37_HUMAN,tr|H7C2V9|H7C2V9_HUMAN,tr|H7BYY2|H7BYY2_HUMAN,tr|H7C231|H7C231_HUMAN" 5 2230.1594 2.13 117674 13963 3 2230.15764 744.3937 BCL-6 corepressor OS=Homo sapiens OX=9606 GN=BCOR PE=1 SV=1 6.47 2525.9 - 1.59E+06 - - - -0.7717 - 3.179 0.55 - 264.1 1 2 0 -0.0017 22 0 0 0 3.01E+08 1.41E+08 - - - 7.4135 1 221125_WJC_METTL3_EV_vs_WT_F08.13969.13969.4 7.92E-09 14/126 R.LLEGEDAHLSSSQFSSGSQSSR.D sp|P02533|K1C14_HUMAN 1 2308.0567 707.44 117678 13969 4 2308.055906 578.0215 "Keratin, type I cytoskeletal 14 OS=Homo sapiens OX=9606 GN=KRT14 PE=1 SV=4" 4.65 2526.7 - 7.08E+06 - - - -0.3644 - 2.837 0.586 - 112.6 1 2 0 -0.0008 22 0 0 0 1.31E+08 1.86E+05 - - - 4.6675 0.9989 221125_WJC_METTL3_EV_vs_WT_F08.13992.13992.4 0.000194 Nov-84 R.GC[160.03]GVVEFKDEEFVKK.A "sp|Q9P2K5|MYEF2_HUMAN,tr|A0A0A0MR39|A0A0A0MR39_HUMAN,tr|A0A0A0MQW0|A0A0A0MQW0_HUMAN" 3 1769.8658 0.67 117694 13992 4 1769.860641 443.4737 Myelin expression factor 2 OS=Homo sapiens OX=9606 GN=MYEF2 PE=1 SV=3 4.87 2529.4 - 545745 - - - -2.9273 - 1.904 0.431 - 54.1 1 2 1 -0.0052 15 0 0 0 9.08E+06 1.35E+07 - - - 3.2064 0.9997 221125_WJC_METTL3_EV_vs_WT_F08.13993.13993.2 5.40E-05 Jul-38 K.SSSATASQPPESLPQPGLQK.S sp|Q5JSZ5|PRC2B_HUMAN 1 2009.0065 4.62 117695 13993 2 2009.00753 1005.5106 Protein PRRC2B OS=Homo sapiens OX=9606 GN=PRRC2B PE=1 SV=2 5.72 2529.5 - 344942 - - - 0.4883 - 1.532 0.487 - 65.9 1 2 0 0.001 20 0 0 0 1.39E+07 3.00E+06 - - - 3.6864 0.9999 221125_WJC_METTL3_EV_vs_WT_F08.13994.13994.3 0.000139 15/64 K.MAPVPLDDSNR[166.11]PASLTK[136.11].D "sp|Q9NYF8|BCLF1_HUMAN,tr|E9PKI6|E9PKI6_HUMAN,tr|A0A1W2PQ43|A0A1W2PQ43_HUMAN,tr|E9PK91|E9PK91_HUMAN,tr|E9PJA7|E9PJA7_HUMAN,tr|E9PK09|E9PK09_HUMAN,tr|E9PQN2|E9PQN2_HUMAN" 7 1828.9472 2.54 117696 13994 3 1828.94816 610.6563 Bcl-2-associated transcription factor 1 OS=Homo sapiens OX=9606 GN=BCLAF1 PE=1 SV=2 5.71 2529.6 - 1.00E+06 - - - 0.5227 - 2.389 0.423 - 174.9 1 2 0 0.001 17 0 0 0 7.29E+07 2.87E+07 - - - 5.4559 1 221125_WJC_METTL3_EV_vs_WT_F08.14003.14003.4 1.03E-06 22/108 K.QALPC[160.03]VAESPTVHVEVHQR[166.11].G sp|Q15645|PCH2_HUMAN 1 2166.0879 0.49 117700 14003 4 2166.083445 542.5293 Pachytene checkpoint protein 2 homolog OS=Homo sapiens OX=9606 GN=TRIP13 PE=1 SV=2 6 2530.8 - 875584 - - - -2.0756 - 3.386 0.552 - 440.9 1 2 0 -0.0045 19 0 0 0 1.33E+07 2.72E+07 - - - 4.4419 1 221125_WJC_METTL3_EV_vs_WT_F08.14004.14004.3 1.78E-11 24/92 R.TQSSASLAASYAAQQHPQAAASYR.G sp|Q96PK6|RBM14_HUMAN 1 2464.1731 1.76 117701 14004 3 2464.16697 822.3983 RNA-binding protein 14 OS=Homo sapiens OX=9606 GN=RBM14 PE=1 SV=2 8.29 2530.9 - 495938 - - - -2.4933 - 4.905 0.717 - 522.8 1 2 0 -0.0061 24 0 0 0 1.47E+07 8.35E+06 - - - 10.2257 0.9999 221125_WJC_METTL3_EV_vs_WT_F08.14005.14005.3 8.87E-08 15/52 K.DKQEVLDQALQQNR.E sp|Q96ST8|CEP89_HUMAN 1 1683.854 1.86 117702 14005 3 1683.853332 562.2919 Centrosomal protein of 89 kDa OS=Homo sapiens OX=9606 GN=CEP89 PE=1 SV=3 4.56 2531 - 678433 - - - -0.4032 - 3.059 0.549 - 332.4 1 2 1 -0.0007 14 0 0 0 1.08E+07 5.84E+06 - - - 7.632 1 221125_WJC_METTL3_EV_vs_WT_F08.14010.14010.3 8.78E-09 23/84 R.SSVETTPSVIQHVGQPPATPAK[136.11].H "sp|Q6W2J9|BCOR_HUMAN,tr|H7BZ37|H7BZ37_HUMAN,tr|H7C2V9|H7C2V9_HUMAN,tr|H7BYY2|H7BYY2_HUMAN,tr|H7C231|H7C231_HUMAN" 5 2238.1736 2.14 117705 14010 3 2238.172175 747.0651 BCL-6 corepressor OS=Homo sapiens OX=9606 GN=BCOR PE=1 SV=1 6.47 2531.7 - 1.60E+06 - - - -0.6193 - 3.883 0.479 - 586.3 1 2 0 -0.0014 22 0 0 0 2.98E+08 1.39E+08 - - - 7.0963 1 221125_WJC_METTL3_EV_vs_WT_F08.14016.14016.3 4.38E-06 16/76 K.SSSATASQPPESLPQPGLQK[136.11].S sp|Q5JSZ5|PRC2B_HUMAN 1 2017.0207 2.54 117709 14016 3 2017.020549 673.3475 Protein PRRC2B OS=Homo sapiens OX=9606 GN=PRRC2B PE=1 SV=2 5.72 2532.5 - 821117 - - - -0.0992 - 2.735 0.469 - 179 1 2 0 -0.0002 20 0 0 0 6.68E+07 2.63E+07 - - - 6.2097 0.9999 221125_WJC_METTL3_EV_vs_WT_F08.14017.14017.3 1.95E-06 15/60 K.TLTTVQGIADDYDK[136.11]K[136.11]K[136.11].L "sp|P41567|EIF1_HUMAN,sp|O60739|EIF1B_HUMAN,tr|K7EM18|K7EM18_HUMAN" 3 1818.9789 0.89 117710 14017 3 1818.97979 607.3336 Eukaryotic translation initiation factor 1 OS=Homo sapiens OX=9606 GN=EIF1 PE=1 SV=1 5.71 2532.6 - 247126 - - - 0.4651 - 2.68 0.522 - 163.3 1 2 1 0.0008 16 0 0 0 3.19E+07 3.58E+07 - - - 6.889 1 221125_WJC_METTL3_EV_vs_WT_F08.14022.14022.3 1.25E-05 17/76 R.SVSSFPVPQDNVDTHPGSGK.E "sp|Q676U5|A16L1_HUMAN,tr|E7EVC7|E7EVC7_HUMAN,tr|C9JAY7|C9JAY7_HUMAN" 3 2053.9705 8.02 117713 14022 3 2053.970979 685.6641 Autophagy-related protein 16-1 OS=Homo sapiens OX=9606 GN=ATG16L1 PE=1 SV=2 5.19 2533.3 - 695929 - - - 0.2342 - 2.71 0.519 - 236.5 1 2 0 0.0005 20 0 0 0 2.36E+07 2.94E+06 - - - 6.7448 1 221125_WJC_METTL3_EV_vs_WT_F08.14024.14024.3 7.78E-09 18/72 K.FNDSEGDDTEETEDYRQFR.K "sp|Q9NYF8|BCLF1_HUMAN,tr|E9PKI6|E9PKI6_HUMAN,tr|A0A1W2PQ43|A0A1W2PQ43_HUMAN,tr|E9PK91|E9PK91_HUMAN,tr|E9PK09|E9PK09_HUMAN,tr|E9PQN2|E9PQN2_HUMAN" 6 2351.9414 1.27 117715 14024 3 2351.937505 784.9878 Bcl-2-associated transcription factor 1 OS=Homo sapiens OX=9606 GN=BCLAF1 PE=1 SV=2 3.85 2533.5 - 638761 - - - -1.6739 - 3.272 0.713 - 405.1 1 2 1 -0.0039 19 0 0 0 9.62E+06 7.60E+06 - - - 9.4004 1 221125_WJC_METTL3_EV_vs_WT_F08.14025.14025.3 1.42E-09 20/84 K.SPSNGVGSLASK[136.11]PVDVASDNVK[136.11].K "sp|Q9NVV0|TM38B_HUMAN,tr|A0A0A0MRS4|A0A0A0MRS4_HUMAN" 2 2143.1092 1.36 117716 14025 3 2143.104353 715.377 Trimeric intracellular cation channel type B OS=Homo sapiens OX=9606 GN=TMEM38B PE=1 SV=1 5.68 2533.7 - 533534 - - - -2.2509 - 3.824 0.562 - 462.8 1 2 0 -0.0048 22 0 0 0 2.46E+07 1.81E+07 - - - 7.9844 0.941 221125_WJC_METTL3_EV_vs_WT_F08.14034.14034.3 1.68E-05 14/48 T.SHK[136.11]PDEIYGMIER[166.11].L sp|Q86U44|MTA70_HUMAN 1 1591.7783 0.001 117723 14034 3 1591.779901 531.6001 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 5.42 2534.8 - 849375 - - - 0.9763 - 2.334 0.262 - 303 1 1 0 0.0016 13 0 0 0 0.00E+00 6.71E+08 - - - 3.7587 0.9997 221125_WJC_METTL3_EV_vs_WT_F08.14037.14037.4 5.04E-06 16/90 R.GTFHDDRDDGVDYWAK.R "tr|H0YF63|H0YF63_HUMAN,tr|E9PK91|E9PK91_HUMAN" 2 1895.8075 2.55 117726 14037 4 1895.808807 474.9591 Bcl-2-associated transcription factor 1 (Fragment) OS=Homo sapiens OX=9606 GN=BCLAF1 PE=1 SV=1 4.28 2535.1 - 1.00E+06 - - - 0.7132 - 2.556 0.45 - 136.8 1 2 1 0.0014 16 0 0 0 6.66E+08 2.61E+08 - - - 3.473 1 221125_WJC_METTL3_EV_vs_WT_F08.14038.14038.3 4.17E-07 21/60 R.GTFHDDRDDGVDYWAK.R "tr|H0YF63|H0YF63_HUMAN,tr|E9PK91|E9PK91_HUMAN" 2 1895.8075 2.31 117727 14038 3 1895.808331 632.9431 Bcl-2-associated transcription factor 1 (Fragment) OS=Homo sapiens OX=9606 GN=BCLAF1 PE=1 SV=1 4.28 2535.2 - 669675 - - - 0.4621 - 3.581 0.694 - 459.7 1 2 1 0.0009 16 0 0 0 6.94E+08 3.01E+08 - - - 9.5503 1 221125_WJC_METTL3_EV_vs_WT_F08.14039.14039.3 1.68E-13 23/84 K.SPSNGVGSLASKPVDVASDNVK.K "sp|Q9NVV0|TM38B_HUMAN,tr|A0A0A0MRS4|A0A0A0MRS4_HUMAN" 2 2127.0808 1.36 117728 14039 3 2127.077117 710.0342 Trimeric intracellular cation channel type B OS=Homo sapiens OX=9606 GN=TMEM38B PE=1 SV=1 5.68 2535.4 - 643616 - - - -1.7207 - 4.618 0.611 - 445.8 1 2 0 -0.0037 22 0 0 0 2.46E+07 1.81E+07 - - - 8.9783 0.9999 221125_WJC_METTL3_EV_vs_WT_F08.14040.14040.2 1.30E-07 15/28 R.STSHK[136.11]PDEIYGMIER[166.11].L sp|Q86U44|MTA70_HUMAN 1 1779.8581 -1 117729 14040 2 1779.856124 890.9363 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 5.42 2535.5 - 443349 - - - -1.0844 - 2.29 0.587 - 477.7 1 2 0 -0.0019 15 0 0 0 0.00E+00 0.00E+00 - - - 5.413 1 221125_WJC_METTL3_EV_vs_WT_F08.14046.14046.3 6.65E-10 14/64 Y.VHYEIDAC[160.03]MDSEAPGSK[136.11].D "sp|Q86U44|MTA70_HUMAN,tr|H0YFV6|H0YFV6_HUMAN" 2 1915.8172 0.01 117733 14046 3 1915.815242 639.613 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 4.31 2536.3 - 2.85E+06 - - - -1.0032 - 3.024 0.708 - 241 1 1 0 -0.0019 17 0 0 0 1.85E+06 1.65E+08 - - - 9.2285 0.9999 221125_WJC_METTL3_EV_vs_WT_F08.14047.14047.4 2.22E-06 14/90 R.GTFHDDR[166.11]DDGVDYWAK[136.11].R "tr|H0YF63|H0YF63_HUMAN,tr|E9PK91|E9PK91_HUMAN" 2 1913.8299 2.53 117734 14047 4 1913.828416 479.4648 Bcl-2-associated transcription factor 1 (Fragment) OS=Homo sapiens OX=9606 GN=BCLAF1 PE=1 SV=1 4.28 2536.3 - 3.10E+06 - - - -0.7885 - 2.175 0.547 - 163.8 1 2 1 -0.0015 16 0 0 0 6.60E+08 2.61E+08 - - - 4.2604 0.9996 221125_WJC_METTL3_EV_vs_WT_F08.14048.14048.3 0.000589 Nov-64 K.MAPVPLDDSNRPASLTK.D "sp|Q9NYF8|BCLF1_HUMAN,tr|E9PKI6|E9PKI6_HUMAN,tr|A0A1W2PQ43|A0A1W2PQ43_HUMAN,tr|E9PK91|E9PK91_HUMAN,tr|E9PJA7|E9PJA7_HUMAN,tr|E9PK09|E9PK09_HUMAN,tr|E9PQN2|E9PQN2_HUMAN" 7 1810.9247 2.54 117735 14048 3 1810.922745 604.6489 Bcl-2-associated transcription factor 1 OS=Homo sapiens OX=9606 GN=BCLAF1 PE=1 SV=2 5.71 2536.4 - 1.57E+06 - - - -1.0983 - 1.983 0.341 - 105.3 1 2 0 -0.002 17 0 0 0 7.29E+07 2.87E+07 - - - 4.0708 1 221125_WJC_METTL3_EV_vs_WT_F08.14049.14049.3 2.66E-09 19/56 K.TK[136.11]PYIQVDIGGGQTK[136.11].T "sp|P11021|BIP_HUMAN,tr|A0A7P0TB36|A0A7P0TB36_HUMAN,tr|A0A7P0TAI0|A0A7P0TAI0_HUMAN" 3 1619.8854 0.49 117736 14049 3 1619.887611 540.9691 Endoplasmic reticulum chaperone BiP OS=Homo sapiens OX=9606 GN=HSPA5 PE=1 SV=2 8.17 2536.5 - 1.29E+06 - - - 1.3822 - 3.569 0.596 - 411.3 1 2 0 0.0022 15 0 0 0 3.90E+07 7.88E+07 - - - 8.5041 0.9759 221125_WJC_METTL3_EV_vs_WT_F08.14059.14059.4 0.00431 16/72 T.SHK[136.11]PDEIYGMIER[166.11].L sp|Q86U44|MTA70_HUMAN 1 1591.7783 0.001 117744 14059 4 1591.77558 398.9519 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 5.42 2537.8 - 1.17E+06 - - - -1.7383 - 2.64 0.381 - 206.4 1 1 0 -0.0028 13 0 0 0 0.00E+00 2.53E+07 - - - 2.9014 1 221125_WJC_METTL3_EV_vs_WT_F08.14077.14077.2 4.14E-08 15/24 T.SHK[136.11]PDEIYGMIER[166.11].L sp|Q86U44|MTA70_HUMAN 1 1591.7783 0.001 117755 14077 2 1591.773328 796.8964 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 5.42 2540.1 - 2.04E+06 - - - -3.1531 - 2.605 0.626 - 500.7 1 1 0 -0.005 13 0 0 0 0.00E+00 7.21E+07 - - - 6.1203 0.9999 221125_WJC_METTL3_EV_vs_WT_F08.14080.14080.3 2.25E-06 17/56 R.STSHK[136.11]PDEIYGMIER[166.11].L sp|Q86U44|MTA70_HUMAN 1 1779.8581 0 117756 14080 3 1779.852556 594.2933 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 5.42 2540.4 - 1.80E+09 - - - -3.089 - 3.083 0.532 - 367.3 1 2 0 -0.0055 15 0 0 0 2.18E+09 6.00E+11 - - - 7.4076 1 221125_WJC_METTL3_EV_vs_WT_F08.14081.14081.2 4.60E-09 21/30 R.GTFHDDRDDGVDYWAK.R "tr|H0YF63|H0YF63_HUMAN,tr|E9PK91|E9PK91_HUMAN" 2 1895.8075 3.64 117757 14081 2 1895.803324 948.911 Bcl-2-associated transcription factor 1 (Fragment) OS=Homo sapiens OX=9606 GN=BCLAF1 PE=1 SV=1 4.28 2540.6 - 3.90E+06 - - - -2.179 - 3.453 0.69 - 1295.5 1 2 1 -0.0041 16 0 0 0 1.01E+08 2.78E+07 - - - 7.1828 0.9998 221125_WJC_METTL3_EV_vs_WT_F08.14082.14082.3 0.00843 19/56 K.TKPYIQVDIGGGQTK.T "sp|P11021|BIP_HUMAN,tr|A0A7P0TB36|A0A7P0TB36_HUMAN,tr|A0A7P0TAI0|A0A7P0TAI0_HUMAN" 3 1603.857 0.49 117758 14082 3 1603.852709 535.6263 Endoplasmic reticulum chaperone BiP OS=Homo sapiens OX=9606 GN=HSPA5 PE=1 SV=2 8.17 2540.7 - 1.94E+06 - - - -2.658 - 2.822 0.372 - 358.8 1 2 0 -0.0043 15 0 0 0 3.90E+07 7.88E+07 - - - 5.3933 0.9997 221125_WJC_METTL3_EV_vs_WT_F08.14087.14087.2 0.000238 28-Nov R.STSHKPDEIYGMIER[166.11].L sp|Q86U44|MTA70_HUMAN 1 1771.8439 - 117760 14087 2 1771.84182 886.9292 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 5.42 2541.3 - 1.11E+07 - - - -1.148 - 1.963 0.456 - 212.3 2 2 0 -0.002 15 0 0 0 - - - - - 3.9321 0.9991 221125_WJC_METTL3_EV_vs_WT_F08.14153.14153.4 0.00114 14/84 R.STSHK[136.11]PDEIYGMIER[166.11].L sp|Q86U44|MTA70_HUMAN 1 1779.8581 0 117774 14153 4 1779.85176 445.9718 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 5.42 2551 - 1.72E+09 - - - -3.5362 - 2.302 0.379 - 157.8 1 2 0 -0.0063 15 0 0 0 1.34E+09 2.76E+11 - - - 2.8214 0.9999 221125_WJC_METTL3_EV_vs_WT_F08.14178.14178.4 3.48E-06 14/96 K.IQVHYYEDGNVQLVSHK.D "sp|P52907|CAZA1_HUMAN,sp|P47755|CAZA2_HUMAN" 2 2028.0065 1.48 117782 14178 4 2028.002695 508.0089 F-actin-capping protein subunit alpha-1 OS=Homo sapiens OX=9606 GN=CAPZA1 PE=1 SV=3 5.99 2554.4 - 4.28E+06 - - - -1.8708 - 2.7 0.44 - 175.9 1 2 0 -0.0038 17 0 0 0 6.94E+07 4.68E+07 - - - 3.3996 0.9994 221125_WJC_METTL3_EV_vs_WT_F08.14180.14180.3 0.000111 14/56 K.TKENVVQSVTSVAEK.T sp|O76070|SYUG_HUMAN 1 1617.8574 2.56 117783 14180 3 1617.854903 540.2931 Gamma-synuclein OS=Homo sapiens OX=9606 GN=SNCG PE=1 SV=2 5.81 2554.6 - 4.89E+06 - - - -1.5224 - 2.405 0.394 - 221.2 1 2 1 -0.0025 15 0 0 0 2.21E+08 8.62E+07 - - - 5.2219 1 221125_WJC_METTL3_EV_vs_WT_F08.14196.14196.3 0.000262 18/64 K.AAQVHAESLQQVVQSQR.E "sp|Q5VT06|CE350_HUMAN,tr|H0Y6Q4|H0Y6Q4_HUMAN" 2 1877.9708 2.57 117787 14196 3 1877.970787 626.9975 Centrosome-associated protein 350 OS=Homo sapiens OX=9606 GN=CEP350 PE=1 SV=1 6.79 2556.9 - 4.88E+06 - - - 0.0075 - 3.276 0.478 - 477 1 2 0 0 17 0 0 0 1.92E+08 7.50E+07 - - - 6.867 0.9998 221125_WJC_METTL3_EV_vs_WT_F08.14207.14207.3 1.20E-05 18/56 K.TK[136.11]ENVVQSVTSVAEK[136.11].T sp|O76070|SYUG_HUMAN 1 1633.8858 2.56 117791 14207 3 1633.882504 545.6359 Gamma-synuclein OS=Homo sapiens OX=9606 GN=SNCG PE=1 SV=2 5.81 2558.2 - 2.40E+06 - - - -1.9965 - 3.205 0.444 - 572.4 1 2 1 -0.0033 15 0 0 0 2.21E+08 8.62E+07 - - - 6.5284 1 221125_WJC_METTL3_EV_vs_WT_F08.14210.14210.3 4.37E-08 16/56 R.STSHKPDEIYGMIER.L sp|Q86U44|MTA70_HUMAN 1 1761.8356 0 117792 14210 3 1761.838121 588.2858 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 5.42 2558.6 - 8.48E+06 - - - 1.44 - 2.907 0.622 - 312 1 2 0 0.0025 15 0 0 0 8.76E+08 2.47E+11 - - - 8.2585 0.9998 221125_WJC_METTL3_EV_vs_WT_F08.14223.14223.4 5.21E-05 17/102 R.SLGSMK[136.11]EENNHLQEELER[166.11].L "sp|Q15643|TRIPB_HUMAN,tr|H0YJ97|H0YJ97_HUMAN" 2 2160.0236 1.38 117794 14223 4 2160.022817 541.0132 Thyroid receptor-interacting protein 11 OS=Homo sapiens OX=9606 GN=TRIP11 PE=1 SV=3 4.64 2560.5 - 4.11E+06 - - - -0.3699 - 2.35 0.467 - 137.2 1 2 1 -0.0008 18 0 0 0 1.50E+08 1.08E+08 - - - 3.5832 1 221125_WJC_METTL3_EV_vs_WT_F08.14255.14255.3 5.25E-11 25/72 R.QAQQERDELADEIANSSGK.G sp|P35579|MYH9_HUMAN 1 2087.972 1.15 117802 14255 3 2087.967916 696.9979 Myosin-9 OS=Homo sapiens OX=9606 GN=MYH9 PE=1 SV=4 4.18 2565 - 2.88E+06 - - - -1.9339 - 4.013 0.637 - 861.6 1 2 1 -0.004 19 0 0 0 1.82E+08 1.59E+08 - - - 9.0546 0.9969 221125_WJC_METTL3_EV_vs_WT_F08.14259.14259.3 7.98E-07 19/48 T.SHK[136.11]PDEIYGMIER[166.11].L sp|Q86U44|MTA70_HUMAN 1 1591.7783 0.001 117805 14259 3 1591.77448 531.6001 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 5.42 2565.5 - 2.41E+06 - - - -2.4294 - 3.294 0.553 - 535.2 1 1 0 -0.0039 13 0 0 0 0.00E+00 6.71E+08 - - - 7.9365 1 221125_WJC_METTL3_EV_vs_WT_F08.14261.14261.2 3.74E-08 17/28 R.STSHK[136.11]PDEIYGMIER[166.11].L sp|Q86U44|MTA70_HUMAN 1 1779.8581 0 117806 14261 2 1779.853428 890.9363 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 5.42 2565.7 - 2.28E+08 - - - -2.5991 - 2.366 0.622 - 549.1 1 2 0 -0.0046 15 0 0 0 1.14E+08 1.36E+11 - - - 5.7509 0.9987 221125_WJC_METTL3_EV_vs_WT_F08.14264.14264.3 6.57E-07 23/72 R.QAQQER[166.11]DELADEIANSSGK[136.11].G sp|P35579|MYH9_HUMAN 1 2105.9944 1.14 117807 14264 3 2105.985205 703.0054 Myosin-9 OS=Homo sapiens OX=9606 GN=MYH9 PE=1 SV=4 4.18 2566.1 - 2.60E+06 - - - -4.3775 - 2.973 0.489 - 426.4 1 2 1 -0.0092 19 0 0 0 1.82E+08 1.59E+08 - - - 6.6662 1 221125_WJC_METTL3_EV_vs_WT_F08.14273.14273.2 8.19E-09 15/22 R.FLEQQNQVLQTK.W "sp|Q7Z794|K2C1B_HUMAN,sp|P04264|K2C1_HUMAN,sp|P35908|K22E_HUMAN" 3 1474.778 999 117810 14273 2 1474.772949 738.3963 "Keratin, type II cytoskeletal 1b OS=Homo sapiens OX=9606 GN=KRT77 PE=1 SV=3" 6 2567.2 - 2.32E+06 - - - -3.4202 - 2.85 0.563 - 678 1 2 0 -0.005 12 0 0 0 1.08E+08 0.00E+00 - - - 5.9534 0.9998 221125_WJC_METTL3_EV_vs_WT_F08.14309.14309.2 2.01E-06 18/28 R.STSHKPDEIYGMIER[166.11].L sp|Q86U44|MTA70_HUMAN 1 1771.8439 - 117823 14309 2 1771.84056 886.9292 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 5.42 2571.9 - 3.31E+06 - - - -1.8591 - 2.465 0.542 - 612.1 1 2 0 -0.0033 15 0 0 0 - - - - - 5.2613 0.9999 221125_WJC_METTL3_EV_vs_WT_F08.14320.14320.4 1.47E-07 28/198 K.LASVPAGGAVAVSAAPGSAAPAAGSAPAAAEEK[136.11]K[136.11].D "sp|P05387|RLA2_HUMAN,tr|H0YDD8|H0YDD8_HUMAN" 2 2917.548 1.68 117827 14320 4 2917.541164 730.3943 60S acidic ribosomal protein P2 OS=Homo sapiens OX=9606 GN=RPLP2 PE=1 SV=1 6.14 2573.4 - 1.64E+06 - - - -2.3431 - 3.358 0.489 - 284.1 1 2 0 -0.0068 34 0 0 0 1.20E+08 7.14E+07 - - - 3.8416 1 221125_WJC_METTL3_EV_vs_WT_F08.14323.14323.3 1.35E-06 38/132 K.LASVPAGGAVAVSAAPGSAAPAAGSAPAAAEEKK.D "sp|P05387|RLA2_HUMAN,tr|H0YDD8|H0YDD8_HUMAN" 2 2901.5196 1.71 117829 14323 3 2901.514904 968.1805 60S acidic ribosomal protein P2 OS=Homo sapiens OX=9606 GN=RPLP2 PE=1 SV=1 6.14 2573.7 - 4.53E+06 - - - -1.6185 - 4.538 0.614 - 825.3 1 2 0 -0.0047 34 0 0 0 2.14E+08 1.25E+08 - - - 8.8639 1 221125_WJC_METTL3_EV_vs_WT_F08.14330.14330.4 1.99E-07 30/198 K.LASVPAGGAVAVSAAPGSAAPAAGSAPAAAEEKK.D "sp|P05387|RLA2_HUMAN,tr|H0YDD8|H0YDD8_HUMAN" 2 2901.5196 1.68 117831 14330 4 2901.51507 726.3872 60S acidic ribosomal protein P2 OS=Homo sapiens OX=9606 GN=RPLP2 PE=1 SV=1 6.14 2574.8 - 4.04E+06 - - - -1.5613 - 3.762 0.501 - 403.1 1 2 0 -0.0045 34 0 0 0 1.20E+08 7.14E+07 - - - 3.9806 0.9732 221125_WJC_METTL3_EV_vs_WT_F08.14340.14340.3 2.72E-05 17/68 R.GK[136.11]VEIDQQQLTQQQLNGN.- "sp|Q8IWS0|PHF6_HUMAN,tr|A0A0D9SGE8|A0A0D9SGE8_HUMAN" 2 2048.0378 0.23 117834 14340 3 2048.036642 683.6865 PHD finger protein 6 OS=Homo sapiens OX=9606 GN=PHF6 PE=1 SV=1 4.37 2576.1 - 981236 - - - -0.5635 - 2.568 0.111 - 269.2 1 2 1 -0.0012 18 0 0 0 1.20E+08 5.27E+08 - - - 2.1257 1 221125_WJC_METTL3_EV_vs_WT_F08.14342.14342.4 4.10E-12 29/120 K.K[136.11]LASQGDSISSQLGPIHPPPR[166.11].T "sp|Q92945|FUBP2_HUMAN,tr|M0R0I5|M0R0I5_HUMAN,tr|M0R0C6|M0R0C6_HUMAN,tr|A0A087WTP3|A0A087WTP3_HUMAN" 4 2202.1876 1.5 117835 14342 4 2202.180662 551.5542 Far upstream element-binding protein 2 OS=Homo sapiens OX=9606 GN=KHSRP PE=1 SV=4 8.75 2576.3 - 2.19E+06 - - - -3.1437 - 4.525 0.64 - 533.3 1 2 0 -0.0069 21 0 0 0 1.22E+08 8.12E+07 - - - 5.2938 1 221125_WJC_METTL3_EV_vs_WT_F08.14345.14345.4 1.02E-10 26/120 K.KLASQGDSISSQLGPIHPPPR.T "sp|Q92945|FUBP2_HUMAN,tr|M0R0I5|M0R0I5_HUMAN,tr|M0R0C6|M0R0C6_HUMAN,tr|A0A087WTP3|A0A087WTP3_HUMAN" 4 2184.1651 1.5 117836 14345 4 2184.164105 547.0486 Far upstream element-binding protein 2 OS=Homo sapiens OX=9606 GN=KHSRP PE=1 SV=4 8.75 2576.7 - 3.84E+06 - - - -0.4624 - 4.793 0.578 - 399.8 1 2 0 -0.001 21 0 0 0 1.15E+08 7.69E+07 - - - 4.7748 0.9997 221125_WJC_METTL3_EV_vs_WT_F08.14354.14354.3 8.98E-06 17/68 R.GKVEIDQQQLTQQQLNGN.- "sp|Q8IWS0|PHF6_HUMAN,tr|A0A0D9SGE8|A0A0D9SGE8_HUMAN" 2 2040.0236 0.23 117840 14354 3 2040.019747 681.0151 PHD finger protein 6 OS=Homo sapiens OX=9606 GN=PHF6 PE=1 SV=1 4.37 2577.9 - 2.50E+06 - - - -1.8867 - 3.39 0.411 - 320.5 1 2 1 -0.0038 18 0 0 0 1.20E+08 5.27E+08 - - - 6.1612 1 221125_WJC_METTL3_EV_vs_WT_F08.14356.14356.3 5.04E-11 40/132 K.LASVPAGGAVAVSAAPGSAAPAAGSAPAAAEEK[136.11]K[136.11].D "sp|P05387|RLA2_HUMAN,tr|H0YDD8|H0YDD8_HUMAN" 2 2917.548 1.71 117841 14356 3 2917.538804 973.5233 60S acidic ribosomal protein P2 OS=Homo sapiens OX=9606 GN=RPLP2 PE=1 SV=1 6.14 2578.1 - 3.61E+06 - - - -3.152 - 4.91 0.668 - 996.4 1 2 0 -0.0092 34 0 0 0 2.14E+08 1.25E+08 - - - 9.6459 1 221125_WJC_METTL3_EV_vs_WT_F08.14357.14357.3 1.41E-11 27/64 K.AVEHMFETEDGSKDEWR.G sp|Q9Y657|SPIN1_HUMAN 1 2064.8847 5.43 117842 14357 3 2064.882892 689.3022 Spindlin-1 OS=Homo sapiens OX=9606 GN=SPIN1 PE=1 SV=3 4.35 2578.3 - 1.35E+06 - - - -0.8848 - 5.071 0.741 - 1529.4 1 2 1 -0.0018 17 0 0 0 4.16E+07 7.66E+06 - - - 10.9025 1 221125_WJC_METTL3_EV_vs_WT_F08.14361.14361.2 6.49E-06 14/34 R.GK[136.11]VEIDQQQLTQQQLNGN.- "sp|Q8IWS0|PHF6_HUMAN,tr|A0A0D9SGE8|A0A0D9SGE8_HUMAN" 2 2048.0378 0.62 117844 14361 2 2048.031997 1025.0262 PHD finger protein 6 OS=Homo sapiens OX=9606 GN=PHF6 PE=1 SV=1 4.37 2578.8 - 1.32E+06 - - - -2.8315 - 3.265 0.562 - 693 1 2 1 -0.0058 18 0 0 0 2.81E+07 4.54E+07 - - - 6.0992 1 221125_WJC_METTL3_EV_vs_WT_F08.14362.14362.4 7.85E-07 25/96 K.AVEHMFETEDGSKDEWR.G sp|Q9Y657|SPIN1_HUMAN 1 2064.8847 2.32 117845 14362 4 2064.886214 517.2285 Spindlin-1 OS=Homo sapiens OX=9606 GN=SPIN1 PE=1 SV=3 4.35 2578.9 - 2.20E+06 - - - 0.724 - 4.534 0.643 - 700.4 1 2 1 0.0015 17 0 0 0 6.53E+07 2.81E+07 - - - 5.3471 1 221125_WJC_METTL3_EV_vs_WT_F08.14363.14363.2 2.29E-09 17/34 R.GKVEIDQQQLTQQQLNGN.- "sp|Q8IWS0|PHF6_HUMAN,tr|A0A0D9SGE8|A0A0D9SGE8_HUMAN" 2 2040.0236 0.62 117846 14363 2 2040.01792 1021.0191 PHD finger protein 6 OS=Homo sapiens OX=9606 GN=PHF6 PE=1 SV=1 4.37 2579 - 926397 - - - -2.7823 - 3.256 0.614 - 508 1 2 1 -0.0057 18 0 0 0 2.81E+07 4.54E+07 - - - 6.4765 1 221125_WJC_METTL3_EV_vs_WT_F08.14364.14364.3 1.97E-11 27/80 K.K[136.11]LASQGDSISSQLGPIHPPPR[166.11].T "sp|Q92945|FUBP2_HUMAN,tr|M0R0I5|M0R0I5_HUMAN,tr|M0R0C6|M0R0C6_HUMAN,tr|A0A087WTP3|A0A087WTP3_HUMAN" 4 2202.1876 2.04 117847 14364 3 2202.184302 735.0698 Far upstream element-binding protein 2 OS=Homo sapiens OX=9606 GN=KHSRP PE=1 SV=4 8.75 2579.1 - 841368 - - - -1.4908 - 4.623 0.648 - 582.9 1 2 0 -0.0033 21 0 0 0 2.69E+07 1.32E+07 - - - 9.4343 0.9999 221125_WJC_METTL3_EV_vs_WT_F08.14365.14365.4 5.98E-07 19/96 K.NREELGFRPEYSASQLK.G "sp|P09874|PARP1_HUMAN,tr|A0A7I2V5E9|A0A7I2V5E9_HUMAN,tr|A0A7I2V625|A0A7I2V625_HUMAN,tr|A0A7I2V3E1|A0A7I2V3E1_HUMAN" 4 2023.0123 1.02 117848 14365 4 2023.014059 506.7604 Poly [ADP-ribose] polymerase 1 OS=Homo sapiens OX=9606 GN=PARP1 PE=1 SV=4 6.23 2579.3 - 825499 - - - 0.868 - 3.262 0.529 - 337.3 1 2 1 0.0018 17 0 0 0 4.30E+08 4.21E+08 - - - 4.2404 1 221125_WJC_METTL3_EV_vs_WT_F08.14368.14368.4 1.77E-08 21/90 K.AQVQLDSDHLEEDIHR.L "sp|P07197|NFM_HUMAN,tr|E7ESP9|E7ESP9_HUMAN,tr|E7EMV2|E7EMV2_HUMAN" 3 1903.9024 2.91 117849 14368 4 1903.898961 476.9829 Neurofilament medium polypeptide OS=Homo sapiens OX=9606 GN=NEFM PE=1 SV=3 4.42 2579.6 - 2.38E+06 - - - -1.8157 - 3.897 0.53 - 527.8 1 2 0 -0.0035 16 0 0 0 4.38E+08 1.51E+08 - - - 4.3173 0.9999 221125_WJC_METTL3_EV_vs_WT_F08.14371.14371.3 1.01E-07 21/64 K.NREELGFRPEYSASQLK.G "sp|P09874|PARP1_HUMAN,tr|A0A7I2V5E9|A0A7I2V5E9_HUMAN,tr|A0A7I2V625|A0A7I2V625_HUMAN,tr|A0A7I2V3E1|A0A7I2V3E1_HUMAN" 4 2023.0123 0.95 117851 14371 3 2023.00842 675.3447 Poly [ADP-ribose] polymerase 1 OS=Homo sapiens OX=9606 GN=PARP1 PE=1 SV=4 6.23 2580 - 1.67E+06 - - - -1.9194 - 3.364 0.499 - 397 1 2 1 -0.0039 17 0 0 0 5.09E+08 5.34E+08 - - - 7.167 0.9996 221125_WJC_METTL3_EV_vs_WT_F08.14372.14372.4 0.000149 15/120 K.NGTQVHGTITGVDVSMNTHLK[136.11].A sp|P62314|SMD1_HUMAN 1 2216.1099 0.96 117852 14372 4 2216.110531 555.0348 Small nuclear ribonucleoprotein Sm D1 OS=Homo sapiens OX=9606 GN=SNRPD1 PE=1 SV=1 6.92 2580.1 - 1.77E+06 - - - 0.278 - 2.896 0.336 - 115.6 1 2 0 0.0006 21 0 0 0 3.14E+07 3.27E+07 - - - 2.502 0.9999 221125_WJC_METTL3_EV_vs_WT_F08.14376.14376.4 7.90E-10 22/96 K.NR[166.11]EELGFR[166.11]PEYSASQLK[136.11].G "sp|P09874|PARP1_HUMAN,tr|A0A7I2V5E9|A0A7I2V5E9_HUMAN,tr|A0A7I2V625|A0A7I2V625_HUMAN,tr|A0A7I2V3E1|A0A7I2V3E1_HUMAN" 4 2051.043 1.02 117854 14376 4 2051.040886 513.768 Poly [ADP-ribose] polymerase 1 OS=Homo sapiens OX=9606 GN=PARP1 PE=1 SV=4 6.23 2580.6 - 3.04E+06 - - - -1.0517 - 3.506 0.58 - 438.4 1 2 1 -0.0022 17 0 0 0 4.30E+08 4.21E+08 - - - 4.7093 1 221125_WJC_METTL3_EV_vs_WT_F08.14377.14377.4 3.41E-08 20/90 K.AQVQLDSDHLEEDIHR[166.11].L "sp|P07197|NFM_HUMAN,tr|E7ESP9|E7ESP9_HUMAN,tr|E7EMV2|E7EMV2_HUMAN" 3 1913.9107 2.91 117855 14377 4 1913.907939 479.4849 Neurofilament medium polypeptide OS=Homo sapiens OX=9606 GN=NEFM PE=1 SV=3 4.42 2580.7 - 1.86E+06 - - - -1.4363 - 3.763 0.496 - 448.2 1 2 0 -0.0027 16 0 0 0 4.38E+08 1.51E+08 - - - 4.0092 0.9997 221125_WJC_METTL3_EV_vs_WT_F08.14381.14381.4 0.000998 15/84 R.STSHK[136.11]PDEIYGMIER[166.11].L sp|Q86U44|MTA70_HUMAN 1 1779.8581 0 117857 14381 4 1779.853754 445.9718 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 5.42 2581.3 - 2.16E+08 - - - -2.4159 - 2.595 0.397 - 155.6 1 2 0 -0.0043 15 0 0 0 1.34E+09 2.76E+11 - - - 3.0215 1 221125_WJC_METTL3_EV_vs_WT_F08.14382.14382.3 4.81E-11 19/60 K.AQVQLDSDHLEEDIHR.L "sp|P07197|NFM_HUMAN,tr|E7ESP9|E7ESP9_HUMAN,tr|E7EMV2|E7EMV2_HUMAN" 3 1903.9024 2.83 117858 14382 3 1903.900951 635.6414 Neurofilament medium polypeptide OS=Homo sapiens OX=9606 GN=NEFM PE=1 SV=3 4.42 2581.4 - 2.66E+06 - - - -0.7705 - 4.027 0.603 - 541 1 2 0 -0.0015 16 0 0 0 1.82E+08 6.42E+07 - - - 8.8368 0.9998 221125_WJC_METTL3_EV_vs_WT_F08.14384.14384.4 4.37E-06 16/78 R.QRPAEIKDYSPYFK.T sp|P02533|K1C14_HUMAN 1 1740.8835 124.87 117860 14384 4 1740.881803 436.2282 "Keratin, type I cytoskeletal 14 OS=Homo sapiens OX=9606 GN=KRT14 PE=1 SV=4" 8.43 2581.5 - 1.38E+06 - - - -0.9869 - 2.648 0.472 - 230.8 1 2 1 -0.0017 14 0 0 0 1.95E+08 1.56E+06 - - - 3.6882 1 221125_WJC_METTL3_EV_vs_WT_F08.14385.14385.4 2.57E-09 31/96 K.AVEHMFETEDGSK[136.11]DEWR[166.11].G sp|Q9Y657|SPIN1_HUMAN 1 2082.9072 2.32 117861 14385 4 2082.905928 521.7341 Spindlin-1 OS=Homo sapiens OX=9606 GN=SPIN1 PE=1 SV=3 4.35 2581.7 - 1.29E+06 - - - -0.6054 - 5.061 0.666 - 1314 1 2 1 -0.0013 17 0 0 0 6.52E+07 2.81E+07 - - - 5.5855 1 221125_WJC_METTL3_EV_vs_WT_F08.14387.14387.4 5.67E-09 20/90 K.K[136.11]HLEINPDHPIVETLR[166.11].Q sp|P08238|HS90B_HUMAN 1 1928.0599 1 117863 14387 4 1928.058425 483.0222 Heat shock protein HSP 90-beta OS=Homo sapiens OX=9606 GN=HSP90AB1 PE=1 SV=4 6.01 2581.9 - 815854 - - - -0.7474 - 3.737 0.531 - 338.8 1 2 0 -0.0014 16 0 0 0 1.03E+08 1.02E+08 - - - 4.3118 1 221125_WJC_METTL3_EV_vs_WT_F08.14388.14388.3 8.28E-06 23/60 K.AQVQLDSDHLEEDIHR[166.11].L "sp|P07197|NFM_HUMAN,tr|E7ESP9|E7ESP9_HUMAN,tr|E7EMV2|E7EMV2_HUMAN" 3 1913.9107 2.83 117864 14388 3 1913.904524 638.9775 Neurofilament medium polypeptide OS=Homo sapiens OX=9606 GN=NEFM PE=1 SV=3 4.42 2582.1 - 808064 - - - -3.2206 - 4.37 0.593 - 878.3 1 2 0 -0.0062 16 0 0 0 1.82E+08 6.42E+07 - - - 8.9337 1 221125_WJC_METTL3_EV_vs_WT_F08.14391.14391.4 1.68E-10 21/114 K.R[166.11]GLLQDDAHPTLVTYADHSK[136.11].L "sp|Q86U44|MTA70_HUMAN,tr|F5H6D8|F5H6D8_HUMAN,tr|H0YFV6|H0YFV6_HUMAN,tr|B4DTN4|B4DTN4_HUMAN" 4 2254.1461 0.02 117865 14391 4 2254.143867 564.5438 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 5.99 2582.5 - 3.16E+06 - - - -0.9973 - 3.687 0.583 - 466.3 1 2 0 -0.0022 20 0 0 0 9.84E+06 5.80E+08 - - - 4.736 0.8016 221125_WJC_METTL3_EV_vs_WT_F08.14393.14393.2 6.47 16-May K.IYEEDQLEK.Q sp|Q8NEH6|MNS1_HUMAN 1 1165.5503 81.97 117867 14393 2 1165.549946 583.7824 Meiosis-specific nuclear structural protein 1 OS=Homo sapiens OX=9606 GN=MNS1 PE=1 SV=2 4 2582.7 - 1.65E+06 - - - -0.29 - 0.927 0.036 - 38.1 12 2 0 -0.0003 9 0 0 0 1.79E+09 2.19E+07 - - - -1.3946 0.9989 221125_WJC_METTL3_EV_vs_WT_F08.14395.14395.3 0.00132 18/96 K.IESPDSSSSSLSSGSSPPGSLPSAR.P sp|Q12948|FOXC1_HUMAN 1 2375.1088 11.75 117869 14395 3 2375.106029 792.7102 Forkhead box protein C1 OS=Homo sapiens OX=9606 GN=FOXC1 PE=1 SV=3 4.37 2583 - 659085 - - - -1.1844 - 3.379 0.623 - 239.8 1 1 0 -0.0028 25 0 0 0 8.73E+07 7.43E+06 - - - 8.2863 1 221125_WJC_METTL3_EV_vs_WT_F08.14399.14399.3 6.40E-16 22/100 S.LHTAANAAATATETTC[160.03]QDVAATPVAR[166.11].Y sp|Q9NP92|RT30_HUMAN 1 2621.2743 1.37 117871 14399 3 2621.273684 874.7654 "39S ribosomal protein S30, mitochondrial OS=Homo sapiens OX=9606 GN=MRPS30 PE=1 SV=2" 5.32 2583.5 - 994553 - - - -0.2342 - 3.962 0.705 - 512.3 1 1 0 -0.0006 26 0 0 0 2.51E+07 1.84E+07 - - - 9.5673 1 221125_WJC_METTL3_EV_vs_WT_F08.14402.14402.3 2.32E-08 22/52 R.QRPAEIKDYSPYFK.T sp|P02533|K1C14_HUMAN 1 1740.8835 39.15 117874 14402 3 1740.882179 581.3018 "Keratin, type I cytoskeletal 14 OS=Homo sapiens OX=9606 GN=KRT14 PE=1 SV=4" 8.43 2583.8 - 1.15E+06 - - - -0.7709 - 3.357 0.591 - 664 1 2 1 -0.0013 14 0 0 0 1.44E+08 3.67E+06 - - - 8.3471 1 221125_WJC_METTL3_EV_vs_WT_F08.14403.14403.3 9.32E-19 30/100 S.LHTAANAAATATETTC[160.03]QDVAATPVAR.Y sp|Q9NP92|RT30_HUMAN 1 2611.266 1.37 117875 14403 3 2611.263713 871.4293 "39S ribosomal protein S30, mitochondrial OS=Homo sapiens OX=9606 GN=MRPS30 PE=1 SV=2" 5.32 2584 - 1.11E+06 - - - -0.8865 - 4.959 0.78 - 1116.1 1 1 0 -0.0023 26 0 0 0 2.51E+07 1.84E+07 - - - 10.9194 1 221125_WJC_METTL3_EV_vs_WT_F08.14408.14408.3 2.08E-13 33/80 K.KLASQGDSISSQLGPIHPPPR.T "sp|Q92945|FUBP2_HUMAN,tr|M0R0I5|M0R0I5_HUMAN,tr|M0R0C6|M0R0C6_HUMAN,tr|A0A087WTP3|A0A087WTP3_HUMAN" 4 2184.1651 1.36 117878 14408 3 2184.166841 729.0623 Far upstream element-binding protein 2 OS=Homo sapiens OX=9606 GN=KHSRP PE=1 SV=4 8.75 2584.6 - 818181 - - - 0.7902 - 5.179 0.684 - 903.8 1 2 0 0.0017 21 0 0 0 3.15E+07 2.32E+07 - - - 10.1083 0.9995 221125_WJC_METTL3_EV_vs_WT_F08.14409.14409.3 0.00149 18/64 K.NR[166.11]EELGFR[166.11]PEYSASQLK[136.11].G "sp|P09874|PARP1_HUMAN,tr|A0A7I2V5E9|A0A7I2V5E9_HUMAN,tr|A0A7I2V625|A0A7I2V625_HUMAN,tr|A0A7I2V3E1|A0A7I2V3E1_HUMAN" 4 2051.043 0.95 117879 14409 3 2051.04178 684.6883 Poly [ADP-ribose] polymerase 1 OS=Homo sapiens OX=9606 GN=PARP1 PE=1 SV=4 6.23 2584.7 - 9.53E+06 - - - -0.6158 - 2.2 0.409 - 255.7 1 2 1 -0.0013 17 0 0 0 5.09E+08 5.34E+08 - - - 5.0915 0.9996 221125_WJC_METTL3_EV_vs_WT_F08.14416.14416.3 0.00249 Dec-60 K.NQNAPDSR[166.11]PEENFFSR[166.11].L sp|Q9HAU5|RENT2_HUMAN 1 1926.8723 0.77 117883 14416 3 1926.86753 643.2981 Regulator of nonsense transcripts 2 OS=Homo sapiens OX=9606 GN=UPF2 PE=1 SV=1 4.68 2585.5 - 574443 - - - -2.4973 - 2.152 0.381 - 167.9 1 2 0 -0.0048 16 0 0 0 2.31E+07 3.02E+07 - - - 4.7529 0.9999 221125_WJC_METTL3_EV_vs_WT_F08.14417.14417.3 1.15E-06 13/64 R.AQVQEFC[160.03]DYGTK[136.11]EEC[160.03]MK[136.11].A "sp|Q86U44|MTA70_HUMAN,tr|H0YFV6|H0YFV6_HUMAN" 2 2137.909 0.04 117884 14417 3 2137.911335 713.6436 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 4.41 2585.6 - 436556 - - - 1.1095 - 2.576 0.568 - 130.4 1 2 1 0.0024 17 0 0 0 2.59E+05 6.75E+06 - - - 7.2625 1 221125_WJC_METTL3_EV_vs_WT_F08.14423.14423.3 1.95E-07 23/76 K.R[166.11]GLLQDDAHPTLVTYADHSK[136.11].L "sp|Q86U44|MTA70_HUMAN,tr|F5H6D8|F5H6D8_HUMAN,tr|H0YFV6|H0YFV6_HUMAN,tr|B4DTN4|B4DTN4_HUMAN" 4 2254.1461 0.001 117887 14423 3 2254.14624 752.3893 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 5.99 2586.4 - 981887 - - - 0.0555 - 4.351 0.603 - 764.2 1 2 0 0.0001 20 0 0 0 0.00E+00 7.17E+07 - - - 8.8301 1 221125_WJC_METTL3_EV_vs_WT_F08.14431.14431.3 4.40E-12 20/92 R.TATYNGPPASPSLSHEATPLSQTR[166.11].S "sp|P27448|MARK3_HUMAN,tr|A0A7I2V3I9|A0A7I2V3I9_HUMAN,tr|H0YIY6|H0YIY6_HUMAN,tr|A0A7I2V5G3|A0A7I2V5G3_HUMAN,tr|A0A7I2YQF4|A0A7I2YQF4_HUMAN,tr|A0A7I2YQF7|A0A7I2YQF7_HUMAN,tr|A0A7I2V4K8|A0A7I2V4K8_HUMAN,tr|A0A7I2V2U9|A0A7I2V2U9_HUMAN,tr|A0A7I2V4G7|A0A7I2V4G7_HUMAN,tr|A0A7I2V2N8|A0A7I2V2N8_HUMAN,tr|H0YJI9|H0YJI9_HUMAN,tr|A0A7I2V409|A0A7I2V409_HUMAN,tr|A0A7I2V4T2|A0A7I2V4T2_HUMAN,tr|A0A7I2V549|A0A7I2V549_HUMAN,tr|A0A7I2V3B9|A0A7I2V3B9_HUMAN,tr|A0A7I2V602|A0A7I2V602_HUMAN,tr|A0A7I2V639|A0A7I2V639_HUMAN,tr|A0A7I2V2E3|A0A7I2V2E3_HUMAN,tr|J3KNR0|J3KNR0_HUMAN,tr|H0YKP9|H0YKP9_HUMAN" 20 2492.2171 1.03 117891 14431 3 2492.220778 831.7463 MAP\microtubule affinity-regulating kinase 3 OS=Homo sapiens OX=9606 GN=MARK3 PE=1 SV=5 6.41 2587.4 - 404527 - - - 1.4754 - 3.801 0.642 - 421.2 1 2 0 0.0037 24 0 0 0 2.28E+07 2.21E+07 - - - 8.7979 1 221125_WJC_METTL3_EV_vs_WT_F08.14432.14432.3 3.18E-09 13/92 R.TATYNGPPASPSLSHEATPLSQTR.S "sp|P27448|MARK3_HUMAN,tr|A0A7I2V3I9|A0A7I2V3I9_HUMAN,tr|H0YIY6|H0YIY6_HUMAN,tr|A0A7I2V5G3|A0A7I2V5G3_HUMAN,tr|A0A7I2YQF4|A0A7I2YQF4_HUMAN,tr|A0A7I2YQF7|A0A7I2YQF7_HUMAN,tr|A0A7I2V4K8|A0A7I2V4K8_HUMAN,tr|A0A7I2V2U9|A0A7I2V2U9_HUMAN,tr|A0A7I2V4G7|A0A7I2V4G7_HUMAN,tr|A0A7I2V2N8|A0A7I2V2N8_HUMAN,tr|H0YJI9|H0YJI9_HUMAN,tr|A0A7I2V409|A0A7I2V409_HUMAN,tr|A0A7I2V4T2|A0A7I2V4T2_HUMAN,tr|A0A7I2V549|A0A7I2V549_HUMAN,tr|A0A7I2V3B9|A0A7I2V3B9_HUMAN,tr|A0A7I2V602|A0A7I2V602_HUMAN,tr|A0A7I2V639|A0A7I2V639_HUMAN,tr|A0A7I2V2E3|A0A7I2V2E3_HUMAN,tr|J3KNR0|J3KNR0_HUMAN,tr|H0YKP9|H0YKP9_HUMAN" 20 2482.2088 1.03 117892 14432 3 2482.209677 828.4102 MAP\microtubule affinity-regulating kinase 3 OS=Homo sapiens OX=9606 GN=MARK3 PE=1 SV=5 6.41 2587.5 - 566169 - - - 0.3408 - 2.977 0.592 - 137 1 2 0 0.0008 24 0 0 0 2.28E+07 2.21E+07 - - - 7.6737 1 221125_WJC_METTL3_EV_vs_WT_F08.14437.14437.4 1.98E-06 14/96 R.VHLPTQPAADTYSEFHK.H "sp|Q6W2J9|BCOR_HUMAN,tr|H7BZ37|H7BZ37_HUMAN,tr|H7C2V9|H7C2V9_HUMAN,tr|H7BYY2|H7BYY2_HUMAN,tr|H7C231|H7C231_HUMAN" 5 1939.9428 1.42 117895 14437 4 1939.941406 485.993 BCL-6 corepressor OS=Homo sapiens OX=9606 GN=BCOR PE=1 SV=1 5.99 2588.2 - 427117 - - - -0.7325 - 2.684 0.486 - 140 1 2 0 -0.0014 17 0 0 0 1.79E+07 1.26E+07 - - - 3.7985 0.9999 221125_WJC_METTL3_EV_vs_WT_F08.14441.14441.2 2.94E-05 14/22 K.NAGVEGSLIVEK.L "sp|P10809|CH60_HUMAN,tr|A0A7I2V2X6|A0A7I2V2X6_HUMAN,tr|A0A7I2YQK6|A0A7I2YQK6_HUMAN,tr|A0A7I2V599|A0A7I2V599_HUMAN" 4 1214.6507 1.47 117897 14441 2 1214.65068 608.3326 "60 kDa heat shock protein, mitochondrial OS=Homo sapiens OX=9606 GN=HSPD1 PE=1 SV=2" 4.53 2588.7 - 854424 - - - 0.0107 - 2.63 0.447 - 709.7 1 2 0 0 12 0 0 0 1.99E+07 1.36E+07 - - - 4.8868 0.7635 221125_WJC_METTL3_EV_vs_WT_F08.14443.14443.3 4.71 Oct-72 R.GLLQDDAHPTLVTYADHSK[136.11].L "sp|Q86U44|MTA70_HUMAN,tr|F5H6D8|F5H6D8_HUMAN,tr|H0YFV6|H0YFV6_HUMAN,tr|B4DTN4|B4DTN4_HUMAN" 4 2088.0367 0.001 117899 14443 3 2088.035762 697.0195 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 5.13 2589 - 1.00E+06 - - - -0.465 - 1.341 0.057 - 63.3 1 2 0 -0.001 19 0 0 0 0.00E+00 2.62E+07 - - - -0.1039 0.9878 221125_WJC_METTL3_EV_vs_WT_F08.14453.14453.3 0.000408 Oct-64 R.VHLPTQPAADTYSEFHK.H "sp|Q6W2J9|BCOR_HUMAN,tr|H7BZ37|H7BZ37_HUMAN,tr|H7C2V9|H7C2V9_HUMAN,tr|H7BYY2|H7BYY2_HUMAN,tr|H7C231|H7C231_HUMAN" 5 1939.9428 0.43 117905 14453 3 1939.926986 647.6549 BCL-6 corepressor OS=Homo sapiens OX=9606 GN=BCOR PE=1 SV=1 5.99 2590.3 - 374844 - - - -8.1657 - 1.96 0.439 - 108.7 1 2 0 -0.0158 17 0 0 0 1.26E+07 2.95E+07 - - - 5.1301 1 221125_WJC_METTL3_EV_vs_WT_F08.14463.14463.3 2.36E-06 14/68 K.KSQIFSTASDNQPTVTIK.V "sp|P11021|BIP_HUMAN,tr|A0A7P0TB36|A0A7P0TB36_HUMAN,tr|A0A7P0TAI0|A0A7P0TAI0_HUMAN" 3 1964.0215 0.57 117911 14463 3 1964.021707 655.6811 Endoplasmic reticulum chaperone BiP OS=Homo sapiens OX=9606 GN=HSPA5 PE=1 SV=2 8.59 2591.6 - 471402 - - - 0.1202 - 2.931 0.522 - 185 1 2 0 0.0002 18 0 0 0 2.75E+07 4.79E+07 - - - 7.0374 1 221125_WJC_METTL3_EV_vs_WT_F08.14468.14468.3 3.19E-07 18/68 K.K[136.11]SQIFSTASDNQPTVTIK[136.11].V "sp|P11021|BIP_HUMAN,tr|A0A7P0TB36|A0A7P0TB36_HUMAN,tr|A0A7P0TAI0|A0A7P0TAI0_HUMAN" 3 1980.0499 0.57 117914 14468 3 1980.049629 661.0239 Endoplasmic reticulum chaperone BiP OS=Homo sapiens OX=9606 GN=HSPA5 PE=1 SV=2 8.59 2592.2 - 836655 - - - -0.1222 - 3.293 0.597 - 358.7 1 2 0 -0.0002 18 0 0 0 2.75E+07 4.79E+07 - - - 8.1636 0.9975 221125_WJC_METTL3_EV_vs_WT_F08.14469.14469.3 0.175 Nov-60 K.KHLEINPDHPIVETLR.Q sp|P08238|HS90B_HUMAN 1 1910.0374 1.01 117915 14469 3 1910.04221 637.6864 Heat shock protein HSP 90-beta OS=Homo sapiens OX=9606 GN=HSP90AB1 PE=1 SV=4 6.01 2592.4 - 418609 - - - 2.5204 - 2.297 0.242 - 107.6 1 2 0 0.0048 16 0 0 0 1.64E+07 1.61E+07 - - - 3.3705 0.9999 221125_WJC_METTL3_EV_vs_WT_F08.14470.14470.3 4.68E-06 14/60 K.NQNAPDSRPEENFFSR.L sp|Q9HAU5|RENT2_HUMAN 1 1906.8558 0.77 117916 14470 3 1906.851211 636.6259 Regulator of nonsense transcripts 2 OS=Homo sapiens OX=9606 GN=UPF2 PE=1 SV=1 4.68 2592.5 - 681303 - - - -2.4076 - 2.468 0.464 - 223.3 1 2 0 -0.0046 16 0 0 0 2.31E+07 3.01E+07 - - - 6.0299 1 221125_WJC_METTL3_EV_vs_WT_F08.14474.14474.4 1.27E-07 15/90 K.KHLEINPDHPIVETLR.Q sp|P08238|HS90B_HUMAN 1 1910.0374 1 117918 14474 4 1910.0397 478.5166 Heat shock protein HSP 90-beta OS=Homo sapiens OX=9606 GN=HSP90AB1 PE=1 SV=4 6.01 2593.1 - 1.79E+06 - - - 1.2063 - 3.268 0.481 - 209.9 1 2 0 0.0023 16 0 0 0 1.03E+08 1.02E+08 - - - 3.8291 0.9997 221125_WJC_METTL3_EV_vs_WT_F08.14482.14482.3 0.0011 Nov-64 R.VHLPTQPAADTYSEFHK[136.11].H "sp|Q6W2J9|BCOR_HUMAN,tr|H7BZ37|H7BZ37_HUMAN,tr|H7C2V9|H7C2V9_HUMAN,tr|H7BYY2|H7BYY2_HUMAN,tr|H7C231|H7C231_HUMAN" 5 1947.957 1.48 117923 14482 3 1947.951246 650.3263 BCL-6 corepressor OS=Homo sapiens OX=9606 GN=BCOR PE=1 SV=1 5.99 2593.9 - 194536 - - - -2.9677 - 2.192 0.424 - 140.4 1 2 0 -0.0058 17 0 0 0 1.21E+07 8.21E+06 - - - 5.2483 0.9999 221125_WJC_METTL3_EV_vs_WT_F08.14483.14483.4 0.000262 Oct-84 K.THINIVVIGHVDSGK[136.11].S "sp|Q05639|EF1A2_HUMAN,sp|P68104|EF1A1_HUMAN,sp|Q5VTE0|EF1A3_HUMAN,tr|A0A2R8Y488|A0A2R8Y488_HUMAN,tr|A0A2R8YDN5|A0A2R8YDN5_HUMAN,tr|A0A7I2V659|A0A7I2V659_HUMAN,tr|A0A7I2V3H3|A0A7I2V3H3_HUMAN,tr|Q5JR01|Q5JR01_HUMAN,tr|A0A2U3TZH3|A0A2U3TZH3_HUMAN,tr|A0A7I2V5N4|A0A7I2V5N4_HUMAN,tr|A0A087WVQ9|A0A087WVQ9_HUMAN,tr|A6PW80|A6PW80_HUMAN,tr|A0A087WV01|A0A087WV01_HUMAN,tr|A0A2R8Y660|A0A2R8Y660_HUMAN,tr|A0A6Q8PFK6|A0A6Q8PFK6_HUMAN" 15 1595.8875 0.3 117924 14483 4 1595.888725 399.9791 Elongation factor 1-alpha 2 OS=Homo sapiens OX=9606 GN=EEF1A2 PE=1 SV=1 6.61 2594.1 - 95765.6 - - - 0.7739 - 2.119 0.433 - 66.7 1 2 0 0.0012 15 0 0 0 3.60E+06 1.21E+07 - - - 3.2632 0.9992 221125_WJC_METTL3_EV_vs_WT_F08.14484.14484.4 8.67E-05 16/96 K.VILHLKEDQTEYLEERR.V "sp|P08238|HS90B_HUMAN,sp|Q58FF7|H90B3_HUMAN,sp|P07900|HS90A_HUMAN,tr|G3V2J8|G3V2J8_HUMAN" 4 2170.1382 0.04 117925 14484 4 2170.141964 543.5418 Heat shock protein HSP 90-beta OS=Homo sapiens OX=9606 GN=HSP90AB1 PE=1 SV=4 4.96 2594.2 - 230039 - - - 1.7197 - 2.953 0.382 - 265.3 1 2 1 0.0037 17 0 0 0 3.92E+06 9.68E+07 - - - 2.9258 0.9999 221125_WJC_METTL3_EV_vs_WT_F08.14487.14487.3 4.24E-06 Sep-84 R.LLEGEDAHLSSSQFSSGSQSSR.D sp|P02533|K1C14_HUMAN 1 2308.0567 999 117926 14487 3 2308.060824 770.3595 "Keratin, type I cytoskeletal 14 OS=Homo sapiens OX=9606 GN=KRT14 PE=1 SV=4" 4.65 2594.6 - 376811 - - - 1.7664 - 1.963 0.543 - 67.3 1 2 0 0.0041 22 0 0 0 1.13E+07 0.00E+00 - - - 6.1918 0.9999 221125_WJC_METTL3_EV_vs_WT_F08.14488.14488.4 0.00233 17/84 R.VLSAPPHFHFGQTNR[166.11].T sp|P26641|EF1G_HUMAN 1 1716.8724 0.93 117927 14488 4 1716.875044 430.2254 Elongation factor 1-gamma OS=Homo sapiens OX=9606 GN=EEF1G PE=1 SV=3 9.73 2594.7 - 360317 - - - 1.5441 - 3.129 0.41 - 344.7 1 2 0 0.0027 15 0 0 0 4.57E+07 4.91E+07 - - - 3.2021 1 221125_WJC_METTL3_EV_vs_WT_F08.14496.14496.3 2.94E-07 Dec-88 K.LPQQDHTTTTDSEMEEPYLQESK.E "sp|Q8IXK0|PHC2_HUMAN,tr|A0A0A0MSI2|A0A0A0MSI2_HUMAN,tr|B3KPJ4|B3KPJ4_HUMAN" 3 2706.1967 5.37 117933 14496 3 2706.197918 903.0728 Polyhomeotic-like protein 2 OS=Homo sapiens OX=9606 GN=PHC2 PE=1 SV=1 4.08 2595.8 - 279245 - - - 0.4608 - 3.054 0.65 - 91.3 1 2 0 0.0012 23 0 0 0 8.37E+06 1.56E+06 - - - 8.4056 0.9998 221125_WJC_METTL3_EV_vs_WT_F08.14499.14499.2 2.53E-07 28-Nov R.STSHK[136.11]PDEIYGMIER[166.11].L sp|Q86U44|MTA70_HUMAN 1 1779.8581 0 117935 14499 2 1779.860764 890.9363 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 5.42 2596.1 - 492930 - - - 1.5226 - 2.067 0.586 - 255.2 1 2 0 0.0027 15 0 0 0 1.14E+08 1.36E+11 - - - 5.1535 1 221125_WJC_METTL3_EV_vs_WT_F08.14504.14504.3 2.29E-08 13/80 R.SMMQDREDQSILC[160.03]TGESGAGK.T "sp|P35579|MYH9_HUMAN,tr|Q5BKV1|Q5BKV1_HUMAN" 2 2298.9879 0.91 117939 14504 3 2298.986204 767.3366 Myosin-9 OS=Homo sapiens OX=9606 GN=MYH9 PE=1 SV=4 4.32 2596.8 - 212335 - - - -0.7295 - 2.727 0.649 - 233.4 1 2 1 -0.0017 21 0 0 0 6.14E+06 6.72E+06 - - - 8.1804 1 221125_WJC_METTL3_EV_vs_WT_F08.14511.14511.3 1.61E-10 16/80 R.SMMQDR[166.11]EDQSILC[160.03]TGESGAGK[136.11].T "sp|P35579|MYH9_HUMAN,tr|Q5BKV1|Q5BKV1_HUMAN" 2 2317.0104 0.91 117944 14511 3 2317.010699 773.3441 Myosin-9 OS=Homo sapiens OX=9606 GN=MYH9 PE=1 SV=4 4.32 2597.7 - 304125 - - - 0.1502 - 3.454 0.762 - 257.8 1 2 1 0.0003 21 0 0 0 6.14E+06 6.72E+06 - - - 10.0072 0.9999 221125_WJC_METTL3_EV_vs_WT_F08.14515.14515.3 2.86E-05 14/76 K.DGLNQTTIPVSPPSTTK[136.11]PSR[166.11].A "sp|Q71RC2|LARP4_HUMAN,tr|X6RLN4|X6RLN4_HUMAN" 2 2113.1134 1.64 117946 14515 3 2113.119276 705.3784 La-related protein 4 OS=Homo sapiens OX=9606 GN=LARP4 PE=1 SV=3 8.75 2598.2 - 458554 - - - 2.7727 - 2.762 0.483 - 161.5 1 2 0 0.0059 20 0 0 0 2.85E+07 1.74E+07 - - - 6.3881 1 221125_WJC_METTL3_EV_vs_WT_F08.14518.14518.3 4.18E-09 15/60 R.FHMDSETHDPIDLQTK[136.11].E "sp|Q9Y2L1|RRP44_HUMAN,tr|G3V1J5|G3V1J5_HUMAN" 2 1920.8767 1.63 117949 14518 3 1920.886387 641.2995 Exosome complex exonuclease RRP44 OS=Homo sapiens OX=9606 GN=DIS3 PE=1 SV=2 4.64 2598.5 - 341501 - - - 5.029 - 2.816 0.673 - 228.9 1 2 0 0.0097 16 0 0 0 1.44E+08 8.82E+07 - - - 8.6971 0.9999 221125_WJC_METTL3_EV_vs_WT_F08.14524.14524.4 7.93E-05 19/84 R.VLSAPPHFHFGQTNR.T sp|P26641|EF1G_HUMAN 1 1706.8641 0.95 117953 14524 4 1706.866745 427.7233 Elongation factor 1-gamma OS=Homo sapiens OX=9606 GN=EEF1G PE=1 SV=3 9.73 2599.3 - 917323 - - - 1.5362 - 2.603 0.442 - 159.2 1 2 0 0.0026 15 0 0 0 4.18E+07 4.40E+07 - - - 3.4147 0.999 221125_WJC_METTL3_EV_vs_WT_F08.14525.14525.4 6.33E-05 15/96 R.RFDAERPVDC[160.03]SVIVVNK.Q "sp|Q9HCD5|NCOA5_HUMAN,tr|Q5JY17|Q5JY17_HUMAN" 2 2003.0258 1.65 117954 14525 4 2003.032328 501.7637 Nuclear receptor coactivator 5 OS=Homo sapiens OX=9606 GN=NCOA5 PE=1 SV=2 6.11 2599.4 - 367718 - - - 3.2366 - 2.512 0.358 - 216.9 1 2 0 0.0065 17 0 0 0 2.72E+07 1.65E+07 - - - 2.66 1 221125_WJC_METTL3_EV_vs_WT_F08.14539.14539.4 1.62E-06 13/90 R.FHMDSETHDPIDLQTK.E "sp|Q9Y2L1|RRP44_HUMAN,tr|G3V1J5|G3V1J5_HUMAN" 2 1912.8625 1.76 117964 14539 4 1912.864948 479.2229 Exosome complex exonuclease RRP44 OS=Homo sapiens OX=9606 GN=DIS3 PE=1 SV=2 4.64 2601.2 - 2.96E+06 - - - 1.2656 - 2.384 0.579 - 119.8 1 2 0 0.0024 16 0 0 0 1.69E+08 9.60E+07 - - - 4.571 1 221125_WJC_METTL3_EV_vs_WT_F08.14541.14541.3 1.31E-16 22/60 R.FHMDSETHDPIDLQTK.E "sp|Q9Y2L1|RRP44_HUMAN,tr|G3V1J5|G3V1J5_HUMAN" 2 1912.8625 1.64 117966 14541 3 1912.863759 638.6281 Exosome complex exonuclease RRP44 OS=Homo sapiens OX=9606 GN=DIS3 PE=1 SV=2 4.64 2601.4 - 2.15E+06 - - - 0.6441 - 4.118 0.774 - 493 1 2 0 0.0012 16 0 0 0 1.44E+08 8.81E+07 - - - 10.8006 1 221125_WJC_METTL3_EV_vs_WT_F08.14542.14542.3 2.65E-06 14/84 R.DPYC[160.03]LGGYHGASHLGGSSC[160.03]STC[160.03].S sp|Q9H7S9|ZN703_HUMAN 1 2341.9151 - 117967 14542 3 2341.914948 781.6456 Zinc finger protein 703 OS=Homo sapiens OX=9606 GN=ZNF703 PE=1 SV=1 5.97 2601.5 - 964485 - - - -0.044 - 2.936 0.675 - 121.1 1 1 0 -0.0001 22 0 0 0 - - - - - 8.6191 1 221125_WJC_METTL3_EV_vs_WT_F08.14543.14543.3 4.74E-06 16/64 R.RFDAERPVDC[160.03]SVIVVNK.Q "sp|Q9HCD5|NCOA5_HUMAN,tr|Q5JY17|Q5JY17_HUMAN" 2 2003.0258 1.61 117968 14543 3 2003.02629 668.6826 Nuclear receptor coactivator 5 OS=Homo sapiens OX=9606 GN=NCOA5 PE=1 SV=2 6.11 2601.7 - 921182 - - - 0.2222 - 3.096 0.51 - 289.5 1 2 0 0.0004 17 0 0 0 2.76E+07 1.71E+07 - - - 7.0809 1 221125_WJC_METTL3_EV_vs_WT_F08.14549.14549.4 1.16E-07 14/90 R.FHMDSETHDPIDLQTK[136.11].E "sp|Q9Y2L1|RRP44_HUMAN,tr|G3V1J5|G3V1J5_HUMAN" 2 1920.8767 1.77 117972 14549 4 1920.874956 481.2265 Exosome complex exonuclease RRP44 OS=Homo sapiens OX=9606 GN=DIS3 PE=1 SV=2 4.64 2602.4 - 2.61E+06 - - - -0.922 - 2.29 0.594 - 151 1 2 0 -0.0018 16 0 0 0 1.69E+08 9.54E+07 - - - 4.6875 0.9998 221125_WJC_METTL3_EV_vs_WT_F08.14550.14550.2 0.000337 20-Oct K.IGGIGTVPVGR.V "sp|Q05639|EF1A2_HUMAN,sp|P68104|EF1A1_HUMAN,sp|Q5VTE0|EF1A3_HUMAN,tr|A0A7I2V659|A0A7I2V659_HUMAN,tr|A0A7I2V3H3|A0A7I2V3H3_HUMAN,tr|A0A2U3TZH3|A0A2U3TZH3_HUMAN,tr|A0A7I2V5N4|A0A7I2V5N4_HUMAN,tr|A0A087WVQ9|A0A087WVQ9_HUMAN" 8 1024.6029 7.98 117973 14550 2 1024.602244 513.3087 Elongation factor 1-alpha 2 OS=Homo sapiens OX=9606 GN=EEF1A2 PE=1 SV=1 9.75 2602.6 - 1.20E+06 - - - -0.6686 - 2.186 0.409 - 270.1 1 2 0 -0.0007 11 0 0 0 4.35E+07 5.45E+06 - - - 4.1774 0.9999 221125_WJC_METTL3_EV_vs_WT_F08.14551.14551.4 9.85E-08 16/96 R.R[166.11]FDAER[166.11]PVDC[160.03]SVIVVNK[136.11].Q "sp|Q9HCD5|NCOA5_HUMAN,tr|Q5JY17|Q5JY17_HUMAN" 2 2031.0566 1.66 117974 14551 4 2031.050959 508.7714 Nuclear receptor coactivator 5 OS=Homo sapiens OX=9606 GN=NCOA5 PE=1 SV=2 6.11 2602.7 - 930447 - - - -2.77 - 2.861 0.504 - 222 1 2 0 -0.0056 17 0 0 0 2.71E+07 1.63E+07 - - - 3.9762 1 221125_WJC_METTL3_EV_vs_WT_F08.14564.14564.3 7.89E-07 16/56 R.STSHK[136.11]PDEIYGMIER[166.11].L sp|Q86U44|MTA70_HUMAN 1 1779.8581 0.02 117984 14564 3 1779.855835 594.2933 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 5.42 2604.2 - 1.85E+07 - - - -1.2467 - 3.051 0.556 - 298.3 1 2 0 -0.0022 15 0 0 0 1.44E+07 7.82E+08 - - - 7.6489 1 221125_WJC_METTL3_EV_vs_WT_F08.14578.14578.3 0.0581 14/56 K.THINIVVIGHVDSGK[136.11].S "sp|Q05639|EF1A2_HUMAN,sp|P68104|EF1A1_HUMAN,sp|Q5VTE0|EF1A3_HUMAN,tr|A0A2R8Y488|A0A2R8Y488_HUMAN,tr|A0A2R8YDN5|A0A2R8YDN5_HUMAN,tr|A0A7I2V659|A0A7I2V659_HUMAN,tr|A0A7I2V3H3|A0A7I2V3H3_HUMAN,tr|Q5JR01|Q5JR01_HUMAN,tr|A0A2U3TZH3|A0A2U3TZH3_HUMAN,tr|A0A7I2V5N4|A0A7I2V5N4_HUMAN,tr|A0A087WVQ9|A0A087WVQ9_HUMAN,tr|A6PW80|A6PW80_HUMAN,tr|A0A087WV01|A0A087WV01_HUMAN,tr|A0A2R8Y660|A0A2R8Y660_HUMAN,tr|A0A6Q8PFK6|A0A6Q8PFK6_HUMAN" 15 1595.8875 0.35 117992 14578 3 1595.887748 532.9698 Elongation factor 1-alpha 2 OS=Homo sapiens OX=9606 GN=EEF1A2 PE=1 SV=1 6.61 2606 - 1.16E+06 - - - 0.1617 - 3.121 0.524 - 251.3 1 2 0 0.0003 15 0 0 0 5.71E+07 1.63E+08 - - - 7.3519 0.9994 221125_WJC_METTL3_EV_vs_WT_F08.14582.14582.4 0.00668 13/102 R.SVTLLIK[136.11]GPNK[136.11]HTLTQIK[136.11].D sp|P40227|TCPZ_HUMAN 1 2014.2365 0.47 117994 14582 4 2014.236412 504.5664 T-complex protein 1 subunit zeta OS=Homo sapiens OX=9606 GN=CCT6A PE=1 SV=3 10.3 2606.6 - 228394 - - - -0.0417 - 2.053 0.399 - 74.3 1 2 2 -0.0001 18 0 0 0 8.25E+06 1.76E+07 - - - 2.9453 1 221125_WJC_METTL3_EV_vs_WT_F08.14593.14593.3 6.26E-09 32/88 R.HGGPGPGGPEPELSPITEGSEAR.A sp|Q8WUF5|IASPP_HUMAN 1 2227.0505 3.38 117999 14593 3 2227.048568 743.3575 RelA-associated inhibitor OS=Homo sapiens OX=9606 GN=PPP1R13L PE=1 SV=4 4.48 2608 - 971163 - - - -0.885 - 5.239 0.688 - 1088.1 1 2 0 -0.002 23 0 0 0 1.22E+08 3.61E+07 - - - 10.0952 0.9986 221125_WJC_METTL3_EV_vs_WT_F08.14609.14609.3 3.52E-05 18/76 R.RLLEGEDAHLSSSQFSSGSQ.S sp|P02533|K1C14_HUMAN 1 2133.9927 20.16 118010 14609 3 2133.992641 712.3382 "Keratin, type I cytoskeletal 14 OS=Homo sapiens OX=9606 GN=KRT14 PE=1 SV=4" 4.65 2609.9 - 748036 - - - -0.023 - 3.333 0.562 - 438.1 1 1 0 0 20 0 0 0 2.72E+07 1.35E+06 - - - 7.7264 0.8968 221125_WJC_METTL3_EV_vs_WT_F08.14610.14610.3 0.761 Nov-76 K.VAPQNDSFGTQLPPMHQQQR[166.11].S tr|C9JSZ1|C9JSZ1_HUMAN 1 2288.0996 0.53 118011 14610 3 2288.110927 763.7071 Far upstream element-binding protein 1 (Fragment) OS=Homo sapiens OX=9606 GN=FUBP1 PE=1 SV=1 6.71 2610.1 - 1.13E+06 - - - 4.9639 - 1.676 0.2 - 76.6 1 2 0 0.0114 20 0 0 0 1.74E+07 3.29E+07 - - - 2.0195 1 221125_WJC_METTL3_EV_vs_WT_F08.14620.14620.3 5.57E-12 29/88 R.HGGPGPGGPEPELSPITEGSEAR[166.11].A sp|Q8WUF5|IASPP_HUMAN 1 2237.0588 3.38 118016 14620 3 2237.055338 746.6935 RelA-associated inhibitor OS=Homo sapiens OX=9606 GN=PPP1R13L PE=1 SV=4 4.48 2611.3 - 1.09E+06 - - - -1.5516 - 4.782 0.56 - 823.7 1 2 0 -0.0035 23 0 0 0 1.22E+08 3.61E+07 - - - 8.4536 0.9999 221125_WJC_METTL3_EV_vs_WT_F08.14622.14622.4 0.000115 17/84 R.STSHK[136.11]PDEIYGMIER[166.11].L sp|Q86U44|MTA70_HUMAN 1 1779.8581 0.04 118017 14622 4 1779.856909 445.9718 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 5.42 2611.6 - 7.45E+06 - - - -0.6433 - 2.59 0.434 - 235.3 1 2 0 -0.0011 15 0 0 0 1.45E+07 4.11E+08 - - - 3.3437 1 221125_WJC_METTL3_EV_vs_WT_F08.14632.14632.3 8.90E-05 13/68 R.EQLSSANHSLQLASQIQK[136.11].A "sp|Q13948|CASP_HUMAN,sp|P39880|CUX1_HUMAN,tr|A0A2R8Y852|A0A2R8Y852_HUMAN,tr|A0A2R8YDI1|A0A2R8YDI1_HUMAN" 4 1989.0371 1.39 118025 14632 3 1989.034416 664.0196 Protein CASP OS=Homo sapiens OX=9606 GN=CUX1 PE=1 SV=2 6.85 2612.8 - 547022 - - - -1.3333 - 2.809 0.468 - 187.7 1 2 0 -0.0027 18 0 0 0 8.22E+07 5.93E+07 - - - 6.3289 0.9993 221125_WJC_METTL3_EV_vs_WT_F08.14639.14639.4 0.000358 12/108 R.VIHLSNLPHSGYSDSAVLK[136.11].L "sp|P43243|MATR3_HUMAN,tr|B3KM87|B3KM87_HUMAN,tr|A8MXP9|A8MXP9_HUMAN,tr|D6RBK5|D6RBK5_HUMAN,tr|A0A0R4J2E8|A0A0R4J2E8_HUMAN,tr|H0Y8T4|H0Y8T4_HUMAN,tr|D6REM6|D6REM6_HUMAN" 7 2044.0833 1.5 118032 14639 4 2044.083604 512.0281 Matrin-3 OS=Homo sapiens OX=9606 GN=MATR3 PE=1 SV=2 6.89 2613.6 - 388774 - - - 0.1536 - 2.357 0.311 - 132.9 1 2 0 0.0003 19 0 0 0 1.60E+07 1.06E+07 - - - 2.2229 0.9997 221125_WJC_METTL3_EV_vs_WT_F08.14643.14643.3 0.000127 13/40 K.IRLENEIQTYR.S "sp|P13645|K1C10_HUMAN,tr|A0A1B0GVI3|A0A1B0GVI3_HUMAN" 2 1433.7627 34.09 118034 14643 3 1433.761631 478.9282 "Keratin, type I cytoskeletal 10 OS=Homo sapiens OX=9606 GN=KRT10 PE=1 SV=6" 6.14 2614.1 - 2.22E+06 - - - -0.7295 - 2.41 0.404 - 337 1 2 1 -0.001 11 0 0 0 5.05E+07 1.48E+06 - - - 5.5428 1 221125_WJC_METTL3_EV_vs_WT_F08.14653.14653.3 1.05E-07 17/68 R.RPTVSSDLENIDTGVNSK.V "sp|O95067|CCNB2_HUMAN,tr|H1UBN3|H1UBN3_HUMAN" 2 1930.9596 1.31 118042 14653 3 1930.959379 644.6605 G2\mitotic-specific cyclin-B2 OS=Homo sapiens OX=9606 GN=CCNB2 PE=1 SV=1 4.56 2615.3 - 263889 - - - -0.1139 - 3.09 0.562 - 293.3 1 2 0 -0.0002 18 0 0 0 8.51E+06 6.47E+06 - - - 7.6149 0.9999 221125_WJC_METTL3_EV_vs_WT_F08.14666.14666.3 6.47E-09 16/80 K.IK[136.11]NENTEGSPQEDGVELEGLK[136.11].Q sp|P11388|TOP2A_HUMAN 1 2301.1307 2.49 118050 14666 3 2301.127264 768.0508 DNA topoisomerase 2-alpha OS=Homo sapiens OX=9606 GN=TOP2A PE=1 SV=3 4.14 2617 - 772800 - - - -1.4932 - 2.998 0.583 - 273.4 1 2 1 -0.0034 21 0 0 0 4.94E+07 1.99E+07 - - - 7.6712 0.9999 221125_WJC_METTL3_EV_vs_WT_F08.14672.14672.3 0.00303 14/52 K.SQIHDIVLVGGSTR[166.11].L "sp|P11142|HSP7C_HUMAN,tr|E9PNE6|E9PNE6_HUMAN,tr|A8K7Q2|A8K7Q2_HUMAN,tr|E9PKE3|E9PKE3_HUMAN,tr|E9PN89|E9PN89_HUMAN" 5 1490.8081 0.14 118054 14672 3 1490.807405 497.9433 Heat shock cognate 71 kDa protein OS=Homo sapiens OX=9606 GN=HSPA8 PE=1 SV=1 6.46 2617.7 - 3.11E+06 - - - -0.44 - 2.033 0.4 - 216.1 1 2 0 -0.0007 14 0 0 0 9.50E+06 6.68E+07 - - - 4.885 1 221125_WJC_METTL3_EV_vs_WT_F08.14675.14675.2 5.35E-13 17/34 K.SPGSSWQEYGPSDTC[160.03]GSR.R sp|Q5JSZ5|PRC2B_HUMAN 1 1956.7908 1.35 118057 14675 2 1956.787231 979.4027 Protein PRRC2B OS=Homo sapiens OX=9606 GN=PRRC2B PE=1 SV=2 4.37 2618.1 - 155477 - - - -1.8336 - 3.337 0.802 - 721.9 1 2 0 -0.0036 18 0 0 0 8.18E+06 6.04E+06 - - - 7.9262 0.9851 221125_WJC_METTL3_EV_vs_WT_F08.14682.14682.3 1.00E-05 15/64 R.AQVQEFC[160.03]DYGTK[136.11]EEC[160.03]MK[136.11].A "sp|Q86U44|MTA70_HUMAN,tr|H0YFV6|H0YFV6_HUMAN" 2 2137.909 0.03 118062 14682 3 2138.902839 713.6436 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 4.41 2618.9 - 445683 - - - 464.8823 - 2.787 0.655 - 211.9 1 2 1 0.9939 17 0 0 0 1.30E+05 4.58E+06 - - - 8.1567 0.998 221125_WJC_METTL3_EV_vs_WT_F08.14683.14683.4 0.0143 9/102 R.GLLPSEGIVHLHSETKPK.T "sp|Q8N6V9|TEX9_HUMAN,tr|H3BS88|H3BS88_HUMAN,tr|H0YKG1|H0YKG1_HUMAN,tr|H0YLZ3|H0YLZ3_HUMAN" 4 1941.0684 24.38 118063 14683 4 1941.069908 486.2744 Testis-expressed protein 9 OS=Homo sapiens OX=9606 GN=TEX9 PE=1 SV=1 6.92 2619 - 232180 - - - 0.797 - 1.925 0.308 - 21.7 3 2 0 0.0015 18 0 0 0 3.69E+06 1.51E+05 - - - 1.7671 0.9997 221125_WJC_METTL3_EV_vs_WT_F08.14690.14690.4 7.91E-06 21/90 R.SKVDEAVAVLQAHQAK.E "sp|Q9H361|PABP3_HUMAN,sp|P11940|PABP1_HUMAN,tr|H0YAS6|H0YAS6_HUMAN,tr|H0YB75|H0YB75_HUMAN,tr|H0YAS7|H0YAS7_HUMAN,tr|A0A7I2YQE4|A0A7I2YQE4_HUMAN,tr|A0A7I2V649|A0A7I2V649_HUMAN,tr|H0YC10|H0YC10_HUMAN,tr|H0YAR2|H0YAR2_HUMAN,tr|E7ERJ7|E7ERJ7_HUMAN,tr|A0A7I2YQ88|A0A7I2YQ88_HUMAN,tr|A0A087WTT1|A0A087WTT1_HUMAN,tr|A0A7I2YQ90|A0A7I2YQ90_HUMAN,tr|A0A7I2V4N4|A0A7I2V4N4_HUMAN,tr|E7EQV3|E7EQV3_HUMAN" 15 1692.9159 1.39 118068 14690 4 1692.913564 424.2362 Polyadenylate-binding protein 3 OS=Homo sapiens OX=9606 GN=PABPC3 PE=1 SV=2 6.47 2619.9 - 499754 - - - -1.3698 - 2.987 0.425 - 459.3 1 2 1 -0.0023 16 0 0 0 1.56E+08 1.12E+08 - - - 3.31 0.9996 221125_WJC_METTL3_EV_vs_WT_F08.14691.14691.4 0.000691 19/90 R.SK[136.11]VDEAVAVLQAHQAK[136.11].E "sp|Q9H361|PABP3_HUMAN,sp|P11940|PABP1_HUMAN,tr|H0YAS6|H0YAS6_HUMAN,tr|H0YB75|H0YB75_HUMAN,tr|H0YAS7|H0YAS7_HUMAN,tr|A0A7I2YQE4|A0A7I2YQE4_HUMAN,tr|A0A7I2V649|A0A7I2V649_HUMAN,tr|H0YC10|H0YC10_HUMAN,tr|H0YAR2|H0YAR2_HUMAN,tr|E7ERJ7|E7ERJ7_HUMAN,tr|A0A7I2YQ88|A0A7I2YQ88_HUMAN,tr|A0A087WTT1|A0A087WTT1_HUMAN,tr|A0A7I2YQ90|A0A7I2YQ90_HUMAN,tr|A0A7I2V4N4|A0A7I2V4N4_HUMAN,tr|E7EQV3|E7EQV3_HUMAN" 15 1708.9443 1.39 118069 14691 4 1708.944313 428.2433 Polyadenylate-binding protein 3 OS=Homo sapiens OX=9606 GN=PABPC3 PE=1 SV=2 6.47 2620 - 458562 - - - 0.0176 - 2.758 0.42 - 341.1 1 2 1 0 16 0 0 0 1.56E+08 1.12E+08 - - - 3.239 1 221125_WJC_METTL3_EV_vs_WT_F08.14696.14696.2 2.06E-09 13/34 K.SPGSSWQEYGPSDTC[160.03]GSR[166.11].R sp|Q5JSZ5|PRC2B_HUMAN 1 1966.7991 1.35 118074 14696 2 1966.798138 984.4068 Protein PRRC2B OS=Homo sapiens OX=9606 GN=PRRC2B PE=1 SV=2 4.37 2620.6 - 206719 - - - -0.4835 - 3.346 0.767 - 428.6 1 2 0 -0.001 18 0 0 0 8.18E+06 6.04E+06 - - - 7.6751 1 221125_WJC_METTL3_EV_vs_WT_F08.14699.14699.3 3.46E-06 25/60 R.SK[136.11]VDEAVAVLQAHQAK[136.11].E "sp|Q9H361|PABP3_HUMAN,sp|P11940|PABP1_HUMAN,tr|H0YAS6|H0YAS6_HUMAN,tr|H0YB75|H0YB75_HUMAN,tr|H0YAS7|H0YAS7_HUMAN,tr|A0A7I2YQE4|A0A7I2YQE4_HUMAN,tr|A0A7I2V649|A0A7I2V649_HUMAN,tr|H0YC10|H0YC10_HUMAN,tr|H0YAR2|H0YAR2_HUMAN,tr|E7ERJ7|E7ERJ7_HUMAN,tr|A0A7I2YQ88|A0A7I2YQ88_HUMAN,tr|A0A087WTT1|A0A087WTT1_HUMAN,tr|A0A7I2YQ90|A0A7I2YQ90_HUMAN,tr|A0A7I2V4N4|A0A7I2V4N4_HUMAN,tr|E7EQV3|E7EQV3_HUMAN" 15 1708.9443 1.27 118075 14699 3 1708.944436 570.6554 Polyadenylate-binding protein 3 OS=Homo sapiens OX=9606 GN=PABPC3 PE=1 SV=2 6.47 2621 - 2.14E+06 - - - 0.0895 - 4.161 0.627 - 726.3 1 2 1 0.0002 16 0 0 0 3.98E+08 3.13E+08 - - - 9.1887 1 221125_WJC_METTL3_EV_vs_WT_F08.14701.14701.3 8.88E-10 19/80 K.IKNENTEGSPQEDGVELEGLK.Q sp|P11388|TOP2A_HUMAN 1 2285.1023 2.48 118077 14701 3 2285.114848 762.708 DNA topoisomerase 2-alpha OS=Homo sapiens OX=9606 GN=TOP2A PE=1 SV=3 4.14 2621.2 - 1.43E+06 - - - 5.4912 - 3.548 0.621 - 424.4 1 2 1 0.0125 21 0 0 0 4.97E+07 2.00E+07 - - - 8.4962 0.9978 221125_WJC_METTL3_EV_vs_WT_F08.14707.14707.4 0.000839 12/102 R.AEDSGEYHC[160.03]VYHFVSAPK.A "sp|Q9Y639|NPTN_HUMAN,tr|Q9UFM8|Q9UFM8_HUMAN" 2 2094.9105 1.13 118083 14707 4 2094.920915 524.7349 Neuroplastin OS=Homo sapiens OX=9606 GN=NPTN PE=1 SV=2 5.28 2621.9 - 317284 - - - 4.9525 - 2.096 0.393 - 90.1 1 2 0 0.0104 18 0 0 0 1.78E+07 1.58E+07 - - - 2.8973 1 221125_WJC_METTL3_EV_vs_WT_F08.14711.14711.3 3.93E-09 17/68 R.EQLSSANHSLQLASQIQK.A "sp|Q13948|CASP_HUMAN,sp|P39880|CUX1_HUMAN,tr|A0A2R8Y852|A0A2R8Y852_HUMAN,tr|A0A2R8YDI1|A0A2R8YDI1_HUMAN" 4 1981.0229 1.39 118085 14711 3 1981.024904 661.3482 Protein CASP OS=Homo sapiens OX=9606 GN=CUX1 PE=1 SV=2 6.85 2622.4 - 1.97E+06 - - - 1.0278 - 3.239 0.572 - 347 1 2 0 0.002 18 0 0 0 8.22E+07 5.93E+07 - - - 7.8432 0.996 221125_WJC_METTL3_EV_vs_WT_F08.14713.14713.4 0.0011 9/108 K.VELKDQTKPTPLILDEQGR.T sp|O43395|PRPF3_HUMAN 1 2179.1848 2.06 118087 14713 4 2179.188166 545.8035 U4\U6 small nuclear ribonucleoprotein Prp3 OS=Homo sapiens OX=9606 GN=PRPF3 PE=1 SV=2 4.78 2622.6 - 938930 - - - 1.5226 - 1.845 0.309 - 55.3 1 2 1 0.0033 19 0 0 0 1.10E+07 5.36E+06 - - - 2.1218 1 221125_WJC_METTL3_EV_vs_WT_F08.14715.14715.3 7.38E-14 21/68 Y.HNLLEGGQEDFESSGAGK.L "sp|P35527|K1C9_HUMAN,tr|K7EQQ3|K7EQQ3_HUMAN" 2 1873.8442 907 118089 14715 3 1873.848882 625.622 "Keratin, type I cytoskeletal 9 OS=Homo sapiens OX=9606 GN=KRT9 PE=1 SV=3" 4.4 2622.9 - 493188 - - - 2.4799 - 4.288 0.701 - 812 1 1 0 0.0046 18 0 0 0 5.15E+07 5.68E+04 - - - 9.9793 0.9386 221125_WJC_METTL3_EV_vs_WT_F08.14726.14726.4 0.00188 8/108 K.VELK[136.11]DQTK[136.11]PTPLILDEQGR[166.11].T sp|O43395|PRPF3_HUMAN 1 2205.2215 2.11 118098 14726 4 2205.228629 552.3127 U4\U6 small nuclear ribonucleoprotein Prp3 OS=Homo sapiens OX=9606 GN=PRPF3 PE=1 SV=2 4.78 2624.3 - 346935 - - - 3.2246 - 2.001 0.23 - 56.7 1 2 1 0.0071 19 0 0 0 1.10E+07 5.24E+06 - - - 1.4606 1 221125_WJC_METTL3_EV_vs_WT_F08.14729.14729.3 1.27E-06 15/56 K.KGDQC[160.03]EFLHEYDMTK.M "sp|O95639|CPSF4_HUMAN,tr|C9K0K2|C9K0K2_HUMAN,tr|B7Z7B0|B7Z7B0_HUMAN,tr|H7C016|H7C016_HUMAN,tr|C9JEV9|C9JEV9_HUMAN" 5 1899.8131 1.41 118101 14729 3 1899.807613 634.2783 Cleavage and polyadenylation specificity factor subunit 4 OS=Homo sapiens OX=9606 GN=CPSF4 PE=1 SV=1 4.75 2624.7 - 207271 - - - -2.9066 - 2.418 0.633 - 231.5 1 2 0 -0.0055 15 0 0 0 6.55E+06 4.65E+06 - - - 7.8997 0.9985 221125_WJC_METTL3_EV_vs_WT_F08.14731.14731.2 2.63E-09 13/30 R.SK[136.11]VDEAVAVLQAHQAK[136.11].E "sp|Q9H361|PABP3_HUMAN,sp|P11940|PABP1_HUMAN,tr|H0YAS6|H0YAS6_HUMAN,tr|H0YB75|H0YB75_HUMAN,tr|H0YAS7|H0YAS7_HUMAN,tr|A0A7I2YQE4|A0A7I2YQE4_HUMAN,tr|A0A7I2V649|A0A7I2V649_HUMAN,tr|H0YC10|H0YC10_HUMAN,tr|H0YAR2|H0YAR2_HUMAN,tr|E7ERJ7|E7ERJ7_HUMAN,tr|A0A7I2YQ88|A0A7I2YQ88_HUMAN,tr|A0A087WTT1|A0A087WTT1_HUMAN,tr|A0A7I2YQ90|A0A7I2YQ90_HUMAN,tr|A0A7I2V4N4|A0A7I2V4N4_HUMAN,tr|E7EQV3|E7EQV3_HUMAN" 15 1708.9443 1.34 118103 14731 2 1708.946632 855.4794 Polyadenylate-binding protein 3 OS=Homo sapiens OX=9606 GN=PABPC3 PE=1 SV=2 6.47 2625 - 138036 - - - 1.3745 - 3.074 0.529 - 473.6 1 2 1 0.0023 16 0 0 0 8.07E+06 6.00E+06 - - - 5.7084 0.9449 221125_WJC_METTL3_EV_vs_WT_F08.14733.14733.3 3.07E-05 13/84 R.LLEGEDAHLSSSQFSSGSQSSR.D sp|P02533|K1C14_HUMAN 1 2308.0567 31.77 118104 14733 3 2309.046935 770.3595 "Keratin, type I cytoskeletal 14 OS=Homo sapiens OX=9606 GN=KRT14 PE=1 SV=4" 4.65 2625.2 - 1.39E+06 - - - 429.0137 - 2.105 0.487 - 110.2 1 2 0 0.9902 22 0 0 0 9.02E+06 2.84E+05 - - - 5.4599 1 221125_WJC_METTL3_EV_vs_WT_F08.14734.14734.4 0.000224 16/84 R.VLSAPPHFHFGQTNR[166.11].T sp|P26641|EF1G_HUMAN 1 1716.8724 -1 118105 14734 4 1716.873942 430.2254 Elongation factor 1-gamma OS=Homo sapiens OX=9606 GN=EEF1G PE=1 SV=3 9.73 2625.3 - 359466 - - - 0.9022 - 2.927 0.486 - 288.4 1 2 0 0.0015 15 0 0 0 0.00E+00 0.00E+00 - - - 3.84 1 221125_WJC_METTL3_EV_vs_WT_F08.14735.14735.4 4.78E-09 13/102 R.AEDSGEYHC[160.03]VYHFVSAPK[136.11].A "sp|Q9Y639|NPTN_HUMAN,tr|Q9UFM8|Q9UFM8_HUMAN" 2 2102.9247 1.12 118106 14735 4 2102.929384 526.7385 Neuroplastin OS=Homo sapiens OX=9606 GN=NPTN PE=1 SV=2 5.28 2625.4 - 978045 - - - 2.2084 - 2.783 0.56 - 107.8 1 2 0 0.0046 18 0 0 0 1.78E+07 1.58E+07 - - - 4.4496 0.9995 221125_WJC_METTL3_EV_vs_WT_F08.14737.14737.4 2.82E-08 19/108 R.SK[136.11]TPVQAAAVSIVEK[136.11]PVTR[166.11].K sp|Q96T58|MINT_HUMAN 1 2006.1734 1.27 118108 14737 4 2006.180702 502.5506 Msx2-interacting protein OS=Homo sapiens OX=9606 GN=SPEN PE=1 SV=1 9.99 2625.7 - 342622 - - - 3.6173 - 3.316 0.531 - 339.9 1 2 1 0.0073 19 0 0 0 1.10E+07 8.70E+06 - - - 4.2513 0.9996 221125_WJC_METTL3_EV_vs_WT_F08.14744.14744.3 9.58E-05 20/60 R.SKVDEAVAVLQAHQAK.E "sp|Q9H361|PABP3_HUMAN,sp|P11940|PABP1_HUMAN,tr|H0YAS6|H0YAS6_HUMAN,tr|H0YB75|H0YB75_HUMAN,tr|H0YAS7|H0YAS7_HUMAN,tr|A0A7I2YQE4|A0A7I2YQE4_HUMAN,tr|A0A7I2V649|A0A7I2V649_HUMAN,tr|H0YC10|H0YC10_HUMAN,tr|H0YAR2|H0YAR2_HUMAN,tr|E7ERJ7|E7ERJ7_HUMAN,tr|A0A7I2YQ88|A0A7I2YQ88_HUMAN,tr|A0A087WTT1|A0A087WTT1_HUMAN,tr|A0A7I2YQ90|A0A7I2YQ90_HUMAN,tr|A0A7I2V4N4|A0A7I2V4N4_HUMAN,tr|E7EQV3|E7EQV3_HUMAN" 15 1692.9159 1.28 118113 14744 3 1692.922447 565.3126 Polyadenylate-binding protein 3 OS=Homo sapiens OX=9606 GN=PABPC3 PE=1 SV=2 6.47 2626.5 - 1.59E+07 - - - 3.8773 - 3.802 0.528 - 502.5 1 2 1 0.0066 16 0 0 0 3.98E+08 3.11E+08 - - - 7.8516 1 221125_WJC_METTL3_EV_vs_WT_F08.14749.14749.2 2.67E-09 18/30 R.SKVDEAVAVLQAHQAK.E "sp|Q9H361|PABP3_HUMAN,sp|P11940|PABP1_HUMAN,tr|H0YAS6|H0YAS6_HUMAN,tr|H0YB75|H0YB75_HUMAN,tr|H0YAS7|H0YAS7_HUMAN,tr|A0A7I2YQE4|A0A7I2YQE4_HUMAN,tr|A0A7I2V649|A0A7I2V649_HUMAN,tr|H0YC10|H0YC10_HUMAN,tr|H0YAR2|H0YAR2_HUMAN,tr|E7ERJ7|E7ERJ7_HUMAN,tr|A0A7I2YQ88|A0A7I2YQ88_HUMAN,tr|A0A087WTT1|A0A087WTT1_HUMAN,tr|A0A7I2YQ90|A0A7I2YQ90_HUMAN,tr|A0A7I2V4N4|A0A7I2V4N4_HUMAN,tr|E7EQV3|E7EQV3_HUMAN" 15 1692.9159 1.34 118118 14749 2 1692.920584 847.4652 Polyadenylate-binding protein 3 OS=Homo sapiens OX=9606 GN=PABPC3 PE=1 SV=2 6.47 2627.2 - 363057 - - - 2.7769 - 3.911 0.713 - 1154.3 1 2 1 0.0047 16 0 0 0 8.07E+06 6.00E+06 - - - 7.6587 1 221125_WJC_METTL3_EV_vs_WT_F08.14751.14751.4 5.49E-07 14/84 K.THINIVVIGHVDSGK[136.11].S "sp|Q05639|EF1A2_HUMAN,sp|P68104|EF1A1_HUMAN,sp|Q5VTE0|EF1A3_HUMAN,tr|A0A2R8Y488|A0A2R8Y488_HUMAN,tr|A0A2R8YDN5|A0A2R8YDN5_HUMAN,tr|A0A7I2V659|A0A7I2V659_HUMAN,tr|A0A7I2V3H3|A0A7I2V3H3_HUMAN,tr|Q5JR01|Q5JR01_HUMAN,tr|A0A2U3TZH3|A0A2U3TZH3_HUMAN,tr|A0A7I2V5N4|A0A7I2V5N4_HUMAN,tr|A0A087WVQ9|A0A087WVQ9_HUMAN,tr|A6PW80|A6PW80_HUMAN,tr|A0A087WV01|A0A087WV01_HUMAN,tr|A0A2R8Y660|A0A2R8Y660_HUMAN,tr|A0A6Q8PFK6|A0A6Q8PFK6_HUMAN" 15 1595.8875 0.35 118120 14751 4 1595.88928 399.9791 Elongation factor 1-alpha 2 OS=Homo sapiens OX=9606 GN=EEF1A2 PE=1 SV=1 6.61 2627.4 - 309063 - - - 1.1216 - 2.686 0.539 - 254.1 1 2 0 0.0018 15 0 0 0 2.68E+07 7.70E+07 - - - 4.2705 1 221125_WJC_METTL3_EV_vs_WT_F08.14752.14752.3 3.22E-08 15/112 K.VDC[160.03]PGPGSGAEGSGPGSVVPGSSGVGTPR.Q "sp|O00268|TAF4_HUMAN,tr|A0A0G2JRY5|A0A0G2JRY5_HUMAN" 2 2580.1874 3.19 118121 14752 3 2580.191531 861.0698 Transcription initiation factor TFIID subunit 4 OS=Homo sapiens OX=9606 GN=TAF4 PE=1 SV=2 4.37 2627.6 - 275295 - - - 1.584 - 2.881 0.67 - 96 1 2 0 0.0041 29 0 0 0 3.44E+06 1.08E+06 - - - 8.4431 1 221125_WJC_METTL3_EV_vs_WT_F08.14753.14753.3 2.58E-07 18/72 R.SKTPVQAAAVSIVEKPVTR.K sp|Q96T58|MINT_HUMAN 1 1980.1368 2.34 118122 14753 3 1980.136629 661.0529 Msx2-interacting protein OS=Homo sapiens OX=9606 GN=SPEN PE=1 SV=1 9.99 2627.7 - 273326 - - - -0.0737 - 3.583 0.64 - 502.3 1 2 1 -0.0001 19 0 0 0 8.34E+06 3.57E+06 - - - 8.8107 0.9995 221125_WJC_METTL3_EV_vs_WT_F08.14756.14756.4 4.43E-05 14/84 K.LKEDISQGVHISVYR.V sp|O43395|PRPF3_HUMAN 1 1742.9315 1.56 118123 14756 4 1742.933784 436.7402 U4\U6 small nuclear ribonucleoprotein Prp3 OS=Homo sapiens OX=9606 GN=PRPF3 PE=1 SV=2 6.75 2628.1 - 1.04E+06 - - - 1.2909 - 2.531 0.406 - 184.6 1 2 1 0.0023 15 0 0 0 8.28E+06 5.29E+06 - - - 3.0915 0.9999 221125_WJC_METTL3_EV_vs_WT_F08.14758.14758.4 2.88E-08 21/108 R.SKTPVQAAAVSIVEKPVTR.K sp|Q96T58|MINT_HUMAN 1 1980.1368 1.26 118125 14758 4 1980.140667 496.0415 Msx2-interacting protein OS=Homo sapiens OX=9606 GN=SPEN PE=1 SV=1 9.99 2628.4 - 752851 - - - 1.9655 - 4.407 0.544 - 435 1 2 1 0.0039 19 0 0 0 1.07E+07 8.48E+06 - - - 4.4616 1 221125_WJC_METTL3_EV_vs_WT_F08.14766.14766.3 0.00015 17/80 K.ENLPVSSDGNLPQQAASAPSR.V sp|Q13625|ASPP2_HUMAN 1 2137.04 1.86 118131 14766 3 2137.039035 713.3539 Apoptosis-stimulating of p53 protein 2 OS=Homo sapiens OX=9606 GN=TP53BP2 PE=1 SV=2 4.37 2629.3 - 949391 - - - -0.4394 - 2.845 0.501 - 331.8 1 2 0 -0.0009 21 0 0 0 9.69E+06 5.21E+06 - - - 6.6321 1 221125_WJC_METTL3_EV_vs_WT_F08.14768.14768.3 2.84E-06 14/68 K.YVHYEIDAC[160.03]MDSEAPGSK[136.11].D "sp|Q86U44|MTA70_HUMAN,tr|H0YFV6|H0YFV6_HUMAN" 2 2078.8805 0.01 118133 14768 3 2078.87583 693.9674 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 4.31 2629.6 - 560692 - - - -2.2426 - 2.502 0.576 - 160.9 1 2 0 -0.0047 18 0 0 0 6.78E+04 8.77E+06 - - - 7.2442 0.9998 221125_WJC_METTL3_EV_vs_WT_F08.14769.14769.3 2.02E-06 18/92 R.IRGPEESQPPQLYAADEEEAPGTR.D sp|Q5RKV6|EXOS6_HUMAN 1 2639.2463 0.56 118134 14769 3 2639.25417 880.7561 Exosome complex component MTR3 OS=Homo sapiens OX=9606 GN=EXOSC6 PE=1 SV=1 4.14 2629.7 - 197660 - - - 2.9671 - 3.742 0.613 - 297.7 1 2 1 0.0078 24 0 0 0 2.80E+06 5.04E+06 - - - 8.4371 0.9986 221125_WJC_METTL3_EV_vs_WT_F08.14770.14770.2 3.19E-05 28-Jul R.STSHK[136.11]PDEIYGMIER[166.11].L sp|Q86U44|MTA70_HUMAN 1 1779.8581 0.001 118135 14770 2 1779.864529 890.9363 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 5.42 2629.8 - 183498 - - - 3.6379 - 1.597 0.53 - 99.7 1 2 0 0.0065 15 0 0 0 0.00E+00 3.72E+06 - - - 4.1045 0.9975 221125_WJC_METTL3_EV_vs_WT_F08.14774.14774.3 0.165 Aug-40 R.LLASTLVHSVK.K "sp|Q9NYF8|BCLF1_HUMAN,tr|E9PKI6|E9PKI6_HUMAN,tr|A0A1W2PQ43|A0A1W2PQ43_HUMAN,tr|E9PK91|E9PK91_HUMAN,tr|E9PJA7|E9PJA7_HUMAN,tr|E9PK09|E9PK09_HUMAN,tr|E9PQN2|E9PQN2_HUMAN" 7 1166.7023 1.5 118137 14774 3 1166.703258 389.908 Bcl-2-associated transcription factor 1 OS=Homo sapiens OX=9606 GN=BCLAF1 PE=1 SV=2 8.76 2630.4 - 198942 - - - 0.8134 - 1.794 0.223 - 41.9 1 2 0 0.0009 11 0 0 0 8.99E+06 6.00E+06 - - - 2.6863 0.9989 221125_WJC_METTL3_EV_vs_WT_F08.14776.14776.4 0.000278 15/114 R.ELK[136.11]EVFGDDSEISK[136.11]ESSGVK[136.11].K sp|O43395|PRPF3_HUMAN 1 2206.1067 2.09 118139 14776 4 2206.108628 552.534 U4\U6 small nuclear ribonucleoprotein Prp3 OS=Homo sapiens OX=9606 GN=PRPF3 PE=1 SV=2 4.36 2630.6 - 433133 - - - 0.8631 - 2.75 0.356 - 184.4 1 2 2 0.0019 20 0 0 0 6.72E+06 3.21E+06 - - - 2.6623 0.822 221125_WJC_METTL3_EV_vs_WT_F08.14783.14783.2 11.4 14-Jun R.K[136.11]QNLLASR.E "sp|O00555|CAC1A_HUMAN,tr|A0A1B0GTI4|A0A1B0GTI4_HUMAN,tr|A0A1C7CYY9|A0A1C7CYY9_HUMAN,tr|A0A1B0GU81|A0A1B0GU81_HUMAN,tr|A0A590UJK2|A0A590UJK2_HUMAN,tr|B5TYJ1|B5TYJ1_HUMAN,tr|A0A1B0GTW2|A0A1B0GTW2_HUMAN,tr|A0A384DVW2|A0A384DVW2_HUMAN,tr|A0A1B0GTN7|A0A1B0GTN7_HUMAN,tr|A0A087WW63|A0A087WW63_HUMAN,tr|A0A1B0GU74|A0A1B0GU74_HUMAN,tr|A0A1B0GUS3|A0A1B0GUS3_HUMAN" 12 936.5596 - 118144 14783 2 936.560418 469.2871 Voltage-dependent P\Q-type calcium channel subunit alpha-1A OS=Homo sapiens OX=9606 GN=CACNA1A PE=1 SV=3 11 2631.5 - 1.35E+06 - - - 0.8585 - 1.01 0.048 - 53.5 22 2 0 0.0008 8 0 0 0 - - - - - -1.1744 0.9985 221125_WJC_METTL3_EV_vs_WT_F08.14786.14786.4 8.65E-05 15/114 R.ELKEVFGDDSEISKESSGVK.K sp|O43395|PRPF3_HUMAN 1 2182.0641 2.09 118147 14786 4 2182.073269 546.5233 U4\U6 small nuclear ribonucleoprotein Prp3 OS=Homo sapiens OX=9606 GN=PRPF3 PE=1 SV=2 4.36 2631.8 - 778625 - - - 4.191 - 2.604 0.468 - 171.5 1 2 2 0.0091 20 0 0 0 6.72E+06 3.21E+06 - - - 3.6169 1 221125_WJC_METTL3_EV_vs_WT_F08.14787.14787.3 8.17E-11 23/64 K.K[136.11]ILDSVGIEADDDR[166.11]LNK[136.11].V sp|P05387|RLA2_HUMAN 1 1926.0268 1.28 118148 14787 3 1926.029001 643.0162 60S acidic ribosomal protein P2 OS=Homo sapiens OX=9606 GN=RPLP2 PE=1 SV=1 4.36 2632 - 678403 - - - 1.1215 - 4.739 0.647 - 498 1 2 1 0.0022 17 0 0 0 3.14E+07 2.45E+07 - - - 9.6833 0.995 221125_WJC_METTL3_EV_vs_WT_F08.14789.14789.4 3.70E-05 13/96 K.QQTDIAVNWAGGLHHAK[136.11].K "sp|Q13547|HDAC1_HUMAN,tr|Q5TEE2|Q5TEE2_HUMAN" 2 1852.9424 1.56 118150 14789 4 1852.945895 464.2429 Histone deacetylase 1 OS=Homo sapiens OX=9606 GN=HDAC1 PE=1 SV=1 6.92 2632.2 - 608973 - - - 1.8975 - 2.272 0.236 - 140.3 1 2 0 0.0035 17 0 0 0 6.27E+07 4.03E+07 - - - 1.5641 0.9998 221125_WJC_METTL3_EV_vs_WT_F08.14790.14790.3 6.35E-12 26/64 K.KILDSVGIEADDDRLNK.V sp|P05387|RLA2_HUMAN 1 1899.9902 1.29 118151 14790 3 1899.996203 634.3373 60S acidic ribosomal protein P2 OS=Homo sapiens OX=9606 GN=RPLP2 PE=1 SV=1 4.36 2632.3 - 557273 - - - 3.1748 - 4.491 0.529 - 1247.8 1 2 1 0.006 17 0 0 0 3.15E+07 2.45E+07 - - - 8.2309 0.9999 221125_WJC_METTL3_EV_vs_WT_F08.14791.14791.3 1.19E-06 13/68 K.VSYIPDEQIAQGPENGRR.G sp|Q9NZI8|IF2B1_HUMAN 1 2028.0025 0.7 118152 14791 3 2028.00617 677.0081 Insulin-like growth factor 2 mRNA-binding protein 1 OS=Homo sapiens OX=9606 GN=IGF2BP1 PE=1 SV=2 4.68 2632.4 - 524088 - - - 1.8259 - 2.285 0.514 - 130.7 1 2 0 0.0037 18 0 0 0 8.84E+06 1.26E+07 - - - 6.3273 0.998 221125_WJC_METTL3_EV_vs_WT_F08.14792.14792.4 6.65E-06 19/96 K.KILDSVGIEADDDRLNK.V sp|P05387|RLA2_HUMAN 1 1899.9902 1.25 118153 14792 4 1899.999306 476.0048 60S acidic ribosomal protein P2 OS=Homo sapiens OX=9606 GN=RPLP2 PE=1 SV=1 4.36 2632.6 - 485631 - - - 4.8079 - 3.115 0.475 - 256.5 1 2 1 0.0091 17 0 0 0 2.30E+07 1.84E+07 - - - 3.7524 0.9999 221125_WJC_METTL3_EV_vs_WT_F08.14794.14794.4 2.04E-05 13/84 K.K[136.11]GDQC[160.03]EFLHEYDMTK[136.11].M "sp|O95639|CPSF4_HUMAN,tr|C9K0K2|C9K0K2_HUMAN,tr|B7Z7B0|B7Z7B0_HUMAN,tr|H7C016|H7C016_HUMAN,tr|C9JEV9|C9JEV9_HUMAN" 5 1915.8415 1.15 118155 14794 4 1915.842452 479.9677 Cleavage and polyadenylation specificity factor subunit 4 OS=Homo sapiens OX=9606 GN=CPSF4 PE=1 SV=1 4.75 2632.8 - 338943 - - - 0.4786 - 2.279 0.439 - 108.6 1 2 0 0.0009 15 0 0 0 4.60E+06 3.99E+06 - - - 3.3415 0.9997 221125_WJC_METTL3_EV_vs_WT_F08.14798.14798.4 0.00179 16/96 K.QQTDIAVNWAGGLHHAK.K "sp|Q13547|HDAC1_HUMAN,tr|Q5TEE2|Q5TEE2_HUMAN" 2 1844.9282 1.56 118157 14798 4 1844.925777 462.2393 Histone deacetylase 1 OS=Homo sapiens OX=9606 GN=HDAC1 PE=1 SV=1 6.92 2633.4 - 1.44E+06 - - - -1.3019 - 2.657 0.346 - 229.6 1 2 0 -0.0024 17 0 0 0 6.23E+07 4.01E+07 - - - 2.5762 0.9998 221125_WJC_METTL3_EV_vs_WT_F08.14799.14799.4 1.88E-05 17/96 K.K[136.11]ILDSVGIEADDDR[166.11]LNK[136.11].V sp|P05387|RLA2_HUMAN 1 1926.0268 1.26 118158 14799 4 1926.030074 482.514 60S acidic ribosomal protein P2 OS=Homo sapiens OX=9606 GN=RPLP2 PE=1 SV=1 4.36 2633.5 - 1.60E+06 - - - 1.6786 - 3.267 0.483 - 153.4 1 2 1 0.0032 17 0 0 0 2.30E+07 1.83E+07 - - - 3.8402 1 221125_WJC_METTL3_EV_vs_WT_F08.14801.14801.3 2.27E-09 21/68 R.GSERPSTSSVSEVWAEDR.L sp|Q9H7E2|TDRD3_HUMAN 1 1977.9028 1.9 118160 14801 3 1977.904923 660.3082 Tudor domain-containing protein 3 OS=Homo sapiens OX=9606 GN=TDRD3 PE=1 SV=1 4.41 2633.7 - 481436 - - - 1.0673 - 3.527 0.513 - 492.4 1 2 0 0.0021 18 0 0 0 1.24E+07 6.51E+06 - - - 7.3975 1 221125_WJC_METTL3_EV_vs_WT_F08.14802.14802.4 1.10E-06 17/102 K.VFQGTDEQLNDLYHNHQR[166.11].T "sp|Q92878|RAD50_HUMAN,tr|E7EN38|E7EN38_HUMAN,tr|A0A494BZX5|A0A494BZX5_HUMAN,tr|A0A494C1B7|A0A494C1B7_HUMAN,tr|E7ESD9|E7ESD9_HUMAN,tr|A0A494C122|A0A494C122_HUMAN,tr|A0A494C0Y7|A0A494C0Y7_HUMAN,tr|A0A1W2PQ90|A0A1W2PQ90_HUMAN" 8 2223.0333 0.93 118161 14802 4 2223.035727 556.7656 DNA repair protein RAD50 OS=Homo sapiens OX=9606 GN=RAD50 PE=1 SV=1 5.21 2633.9 - 476931 - - - 1.1084 - 2.96 0.536 - 303.2 1 2 0 0.0025 18 0 0 0 1.56E+07 1.68E+07 - - - 4.2624 0.9857 221125_WJC_METTL3_EV_vs_WT_F08.14803.14803.4 0.00445 Dec-84 R.VKEDDLDVVLSPQRR.S "sp|Q9NRA8|4ET_HUMAN,tr|B1AKL5|B1AKL5_HUMAN,tr|B1AKL4|B1AKL4_HUMAN" 3 1767.9479 1.08 118162 14803 4 1767.955418 442.9943 Eukaryotic translation initiation factor 4E transporter OS=Homo sapiens OX=9606 GN=EIF4ENIF1 PE=1 SV=2 4.68 2634 - 431519 - - - 4.2456 - 1.779 0.34 - 66.4 1 2 1 0.0075 15 0 0 0 5.02E+06 4.63E+06 - - - 2.3894 0.9983 221125_WJC_METTL3_EV_vs_WT_F08.14804.14804.3 0.000308 Sep-60 K.DEESGSGSNPFQHLEK[136.11].S sp|Q9UBF2|COPG2_HUMAN 1 1767.7791 0.24 118163 14804 3 1767.785589 590.267 Coatomer subunit gamma-2 OS=Homo sapiens OX=9606 GN=COPG2 PE=1 SV=1 4.4 2634.1 - 375182 - - - 3.6583 - 1.842 0.378 - 80.1 1 2 0 0.0065 16 0 0 0 1.40E+06 5.96E+06 - - - 4.3199 1 221125_WJC_METTL3_EV_vs_WT_F08.14806.14806.3 2.27E-05 14/80 R.SSAQLQTNYPSSDNSLYTNAK[136.11].G "sp|P61244|MAX_HUMAN,tr|G3V302|G3V302_HUMAN,tr|G3V5L1|G3V5L1_HUMAN" 3 2296.0699 0.99 118165 14806 3 2296.07013 766.3639 Protein max OS=Homo sapiens OX=9606 GN=MAX PE=1 SV=1 5.55 2634.4 - 304060 - - - 0.1071 - 3.247 0.55 - 283.9 1 2 0 0.0002 21 0 0 0 4.54E+06 4.59E+06 - - - 7.4954 1 221125_WJC_METTL3_EV_vs_WT_F08.14811.14811.3 1.96E-06 16/56 R.STSHK[136.11]PDEIYGMIER[166.11].L sp|Q86U44|MTA70_HUMAN 1 1779.8581 0.02 118169 14811 3 1779.861286 594.2933 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 5.42 2635 - 4.11E+06 - - - 1.8159 - 3.252 0.578 - 323.1 1 2 0 0.0032 15 0 0 0 2.90E+06 1.68E+08 - - - 8.0604 0.9998 221125_WJC_METTL3_EV_vs_WT_F08.14814.14814.4 0.00674 14/102 K.VFQGTDEQLNDLYHNHQR.T "sp|Q92878|RAD50_HUMAN,tr|E7EN38|E7EN38_HUMAN,tr|A0A494BZX5|A0A494BZX5_HUMAN,tr|A0A494C1B7|A0A494C1B7_HUMAN,tr|E7ESD9|E7ESD9_HUMAN,tr|A0A494C122|A0A494C122_HUMAN,tr|A0A494C0Y7|A0A494C0Y7_HUMAN,tr|A0A1W2PQ90|A0A1W2PQ90_HUMAN" 8 2213.025 0.94 118171 14814 4 2213.032668 554.2635 DNA repair protein RAD50 OS=Homo sapiens OX=9606 GN=RAD50 PE=1 SV=1 5.21 2635.3 - 1.01E+06 - - - 3.4681 - 3.461 0.469 - 186.7 1 2 0 0.0077 18 0 0 0 1.57E+07 1.68E+07 - - - 3.7314 0.9999 221125_WJC_METTL3_EV_vs_WT_F08.14816.14816.3 6.78E-08 18/64 K.QQTDIAVNWAGGLHHAK[136.11].K "sp|Q13547|HDAC1_HUMAN,tr|Q5TEE2|Q5TEE2_HUMAN" 2 1852.9424 1.41 118173 14816 3 1852.947822 618.6547 Histone deacetylase 1 OS=Homo sapiens OX=9606 GN=HDAC1 PE=1 SV=1 6.92 2635.5 - 787590 - - - 2.9375 - 2.79 0.548 - 327.2 1 2 0 0.0054 17 0 0 0 2.50E+07 1.77E+07 - - - 7.2402 0.9933 221125_WJC_METTL3_EV_vs_WT_F08.14817.14817.4 6.99E-05 16/78 R.R[166.11]C[160.03]ILPFDK[136.11]ETGFHR[166.11].G "sp|Q9GZT3|SLIRP_HUMAN,tr|H0YJW7|H0YJW7_HUMAN,tr|A0A087WUN7|A0A087WUN7_HUMAN,tr|G3V2S9|G3V2S9_HUMAN,tr|H0YJ40|H0YJ40_HUMAN,tr|G3V4X6|G3V4X6_HUMAN" 6 1802.9244 1.07 118174 14817 4 1802.929451 451.7384 "SRA stem-loop-interacting RNA-binding protein, mitochondrial OS=Homo sapiens OX=9606 GN=SLIRP PE=1 SV=1" 8.23 2635.6 - 524986 - - - 2.7749 - 3.023 0.301 - 263.9 1 2 1 0.005 14 0 0 0 8.13E+06 7.57E+06 - - - 2.2471 1 221125_WJC_METTL3_EV_vs_WT_F08.14818.14818.3 5.17E-06 21/68 R.GSER[166.11]PSTSSVSEVWAEDR[166.11].L sp|Q9H7E2|TDRD3_HUMAN 1 1997.9194 2 118175 14818 3 1997.925093 666.9804 Tudor domain-containing protein 3 OS=Homo sapiens OX=9606 GN=TDRD3 PE=1 SV=1 4.41 2635.8 - 506620 - - - 2.8735 - 3.83 0.579 - 501 1 2 0 0.0057 18 0 0 0 1.29E+07 6.46E+06 - - - 8.3376 0.9996 221125_WJC_METTL3_EV_vs_WT_F08.14820.14820.3 7.51E-06 Oct-60 K.NRAEQWNVNYVETSAK.T "sp|P11233|RALA_HUMAN,tr|H7C3P7|H7C3P7_HUMAN" 2 1907.9126 2.2 118177 14820 3 1907.917398 636.9781 Ras-related protein Ral-A OS=Homo sapiens OX=9606 GN=RALA PE=1 SV=1 6.14 2636 - 186157 - - - 2.5206 - 2.346 0.52 - 124.9 1 2 1 0.0048 16 0 0 0 2.46E+06 1.12E+06 - - - 6.5241 0.9912 221125_WJC_METTL3_EV_vs_WT_F08.14831.14831.3 9.00E-05 13/60 L.RETNLDSLPLVDTHSK.R sp|P08670|VIME_HUMAN 1 1823.9377 1.49 118186 14831 3 1823.942703 608.9865 Vimentin OS=Homo sapiens OX=9606 GN=VIM PE=1 SV=4 5.38 2637.5 - 266470 - - - 2.7205 - 2.591 0.509 - 299.4 1 1 0 0.005 16 0 0 0 1.31E+07 8.74E+06 - - - 6.6563 0.9959 221125_WJC_METTL3_EV_vs_WT_F08.14838.14838.4 0.0324 14/72 K.ELHINLIPNK[136.11]QDR[166.11].T "sp|P07900|HS90A_HUMAN,tr|G3V2J8|G3V2J8_HUMAN" 2 1606.891 0.87 118191 14838 4 1606.895354 402.73 Heat shock protein HSP 90-alpha OS=Homo sapiens OX=9606 GN=HSP90AA1 PE=1 SV=5 6.85 2638.4 - 700451 - - - 2.704 - 2.153 0.338 - 191.7 1 2 1 0.0043 13 0 0 0 3.03E+07 3.49E+07 - - - 2.4511 0.8106 221125_WJC_METTL3_EV_vs_WT_F08.14841.14841.4 2.70E-06 17/90 L.RETNLDSLPLVDTHSK.R sp|P08670|VIME_HUMAN 1 1823.9377 1.64 118194 14841 4 1823.949881 456.9917 Vimentin OS=Homo sapiens OX=9606 GN=VIM PE=1 SV=4 5.38 2638.8 - 442759 - - - 6.6559 - 3.04 0.464 - 293.3 1 1 0 0.0121 16 0 0 0 1.27E+07 7.77E+06 - - - 3.653 0.9999 221125_WJC_METTL3_EV_vs_WT_F08.14842.14842.3 2.23E-09 18/68 K.VFQGTDEQLNDLYHNHQR[166.11].T "sp|Q92878|RAD50_HUMAN,tr|E7EN38|E7EN38_HUMAN,tr|A0A494BZX5|A0A494BZX5_HUMAN,tr|A0A494C1B7|A0A494C1B7_HUMAN,tr|E7ESD9|E7ESD9_HUMAN,tr|A0A494C122|A0A494C122_HUMAN,tr|A0A494C0Y7|A0A494C0Y7_HUMAN,tr|A0A1W2PQ90|A0A1W2PQ90_HUMAN" 8 2223.0333 1 118195 14842 3 2223.02608 742.0184 DNA repair protein RAD50 OS=Homo sapiens OX=9606 GN=RAD50 PE=1 SV=1 5.21 2638.9 - 424535 - - - -3.2312 - 3.235 0.584 - 392.3 1 2 0 -0.0072 18 0 0 0 2.49E+06 2.49E+06 - - - 7.9725 0.9924 221125_WJC_METTL3_EV_vs_WT_F08.14843.14843.4 0.00449 14/72 K.ELHINLIPNKQDR.T "sp|P07900|HS90A_HUMAN,tr|G3V2J8|G3V2J8_HUMAN" 2 1588.8685 0.69 118196 14843 4 1588.872547 398.2244 Heat shock protein HSP 90-alpha OS=Homo sapiens OX=9606 GN=HSP90AA1 PE=1 SV=5 6.85 2639 - 402240 - - - 2.5225 - 2.005 0.303 - 114.7 1 2 1 0.004 13 0 0 0 2.37E+07 3.44E+07 - - - 2.1201 0.9968 221125_WJC_METTL3_EV_vs_WT_F08.14849.14849.3 0.000118 Nov-64 R.NQELSQSVSSTTR[166.11]PLLR[166.11].Q "sp|P82094|TMF1_HUMAN,tr|A0A2R8Y7M0|A0A2R8Y7M0_HUMAN" 2 1935.0288 2.52 118202 14849 3 1935.042009 646.0169 TATA element modulatory factor OS=Homo sapiens OX=9606 GN=TMF1 PE=1 SV=2 9.6 2639.8 - 177435 - - - 6.804 - 2.475 0.435 - 159.3 1 2 0 0.0132 17 0 0 0 2.82E+06 1.12E+06 - - - 5.6756 1 221125_WJC_METTL3_EV_vs_WT_F08.14853.14853.3 1.27E-10 16/76 R.ETDC[160.03]GVHINAGPEIGVASTK.A "sp|Q06210|GFPT1_HUMAN,sp|O94808|GFPT2_HUMAN,tr|A0A6I8PRN4|A0A6I8PRN4_HUMAN,tr|A0A6I8PTT9|A0A6I8PTT9_HUMAN" 4 2053.9739 1.17 118204 14853 3 2053.978613 685.6652 Glutamine--fructose-6-phosphate aminotransferase [isomerizing] 1 OS=Homo sapiens OX=9606 GN=GFPT1 PE=1 SV=3 4.65 2640.4 - 657365 - - - 2.3097 - 3.221 0.628 - 284.9 1 2 0 0.0047 20 0 0 0 3.44E+07 2.93E+07 - - - 8.378 0.9958 221125_WJC_METTL3_EV_vs_WT_F08.14854.14854.3 0.00364 Oct-44 R.DLDELSRYPEDK.L "sp|P43243|MATR3_HUMAN,tr|A8MXP9|A8MXP9_HUMAN,tr|D6R991|D6R991_HUMAN,tr|A0A0R4J2E8|A0A0R4J2E8_HUMAN,tr|D6REM6|D6REM6_HUMAN" 5 1478.6889 1.33 118205 14854 3 1478.694347 493.9036 Matrin-3 OS=Homo sapiens OX=9606 GN=MATR3 PE=1 SV=2 4.11 2640.5 - 497134 - - - 3.6816 - 2.108 0.381 - 95.7 1 2 1 0.0054 12 0 0 0 1.71E+07 1.28E+07 - - - 4.8533 0.9982 221125_WJC_METTL3_EV_vs_WT_F08.14855.14855.3 0.000139 Dec-48 K.ELHINLIPNK[136.11]QDR[166.11].T "sp|P07900|HS90A_HUMAN,tr|G3V2J8|G3V2J8_HUMAN" 2 1606.891 0.68 118206 14855 3 1606.897235 536.6376 Heat shock protein HSP 90-alpha OS=Homo sapiens OX=9606 GN=HSP90AA1 PE=1 SV=5 6.85 2640.6 - 735569 - - - 3.8746 - 2.348 0.446 - 190.2 1 2 1 0.0062 13 0 0 0 1.97E+07 2.88E+07 - - - 5.825 0.9982 221125_WJC_METTL3_EV_vs_WT_F08.14856.14856.3 0.00673 Dec-44 R.DLDELSR[166.11]YPEDK[136.11].L "sp|P43243|MATR3_HUMAN,tr|A8MXP9|A8MXP9_HUMAN,tr|D6R991|D6R991_HUMAN,tr|A0A0R4J2E8|A0A0R4J2E8_HUMAN,tr|D6REM6|D6REM6_HUMAN" 5 1496.7114 1.32 118207 14856 3 1496.716415 499.9111 Matrin-3 OS=Homo sapiens OX=9606 GN=MATR3 PE=1 SV=2 4.11 2640.7 - 456968 - - - 3.3687 - 2.046 0.439 - 133.3 1 2 1 0.005 12 0 0 0 1.71E+07 1.29E+07 - - - 5.4173 1 221125_WJC_METTL3_EV_vs_WT_F08.14857.14857.3 2.82E-07 16/100 K.TPTPSTPGDTQPNTPAPVPPAEDGIK.L "sp|Q14839|CHD4_HUMAN,tr|A0A2R8Y4X2|A0A2R8Y4X2_HUMAN,tr|A0A2U3TZM0|A0A2U3TZM0_HUMAN,tr|A0A2R8Y5M9|A0A2R8Y5M9_HUMAN,tr|A0A2R8Y445|A0A2R8Y445_HUMAN,tr|A0A2R8YD40|A0A2R8YD40_HUMAN,tr|A0A2R8Y5J0|A0A2R8Y5J0_HUMAN,tr|A0A2R8Y425|A0A2R8Y425_HUMAN,tr|A0A2R8YFK9|A0A2R8YFK9_HUMAN,tr|A0A2R8Y8C1|A0A2R8Y8C1_HUMAN,tr|A0A0C4DGG9|A0A0C4DGG9_HUMAN,tr|A0A2R8YDW2|A0A2R8YDW2_HUMAN,tr|F5GWX5|F5GWX5_HUMAN,tr|A0A2R8YER1|A0A2R8YER1_HUMAN,tr|A0A2R8Y7M9|A0A2R8Y7M9_HUMAN,tr|A0A2R8Y521|A0A2R8Y521_HUMAN,tr|A0A2R8Y212|A0A2R8Y212_HUMAN,tr|A0A2R8YE38|A0A2R8YE38_HUMAN" 18 2584.2657 1.62 118208 14857 3 2584.272709 862.4292 Chromodomain-helicase-DNA-binding protein 4 OS=Homo sapiens OX=9606 GN=CHD4 PE=1 SV=2 4.03 2640.9 - 306718 - - - 2.7211 - 2.625 0.624 - 130.5 1 2 0 0.007 26 0 0 0 6.33E+06 3.92E+06 - - - 7.7153 0.9998 221125_WJC_METTL3_EV_vs_WT_F08.14859.14859.3 1.01E-07 16/68 K.GK[136.11]EDEGEEAASPMLQIQR[166.11].D "sp|Q14204|DYHC1_HUMAN,tr|A0A7P0T8N2|A0A7P0T8N2_HUMAN,tr|A0A7P0T9C4|A0A7P0T9C4_HUMAN,tr|A0A7P0TBJ7|A0A7P0TBJ7_HUMAN,tr|A0A804HHY6|A0A804HHY6_HUMAN,tr|A0A7P0T9K2|A0A7P0T9K2_HUMAN,tr|A0A7P0TB64|A0A7P0TB64_HUMAN,tr|A0A2R8Y706|A0A2R8Y706_HUMAN,tr|A0A7P0T916|A0A7P0T916_HUMAN,tr|A0A7P0TB75|A0A7P0TB75_HUMAN,tr|A0A7P0T8W5|A0A7P0T8W5_HUMAN,tr|A0A7P0TAF3|A0A7P0TAF3_HUMAN,tr|A0A7P0T9F1|A0A7P0T9F1_HUMAN,tr|A0A7P0TAW9|A0A7P0TAW9_HUMAN,tr|A0A2R8YGC7|A0A2R8YGC7_HUMAN,tr|A0A7P0TA13|A0A7P0TA13_HUMAN,tr|A0A7P0TAV5|A0A7P0TAV5_HUMAN,tr|A0A7P0T7V5|A0A7P0T7V5_HUMAN,tr|A0A7P0T9R4|A0A7P0T9R4_HUMAN,tr|A0A2R8Y5T0|A0A2R8Y5T0_HUMAN,tr|A0A7P0T990|A0A7P0T990_HUMAN,tr|A0A7P0T942|A0A7P0T942_HUMAN,tr|A0A2R8YFZ7|A0A2R8YFZ7_HUMAN,tr|A0A7P0T825|A0A7P0T825_HUMAN,tr|A0A2R8Y6H2|A0A2R8Y6H2_HUMAN,tr|A0A7P0TAM4|A0A7P0TAM4_HUMAN" 26 2004.9541 1.09 118210 14859 3 2004.959246 669.3253 Cytoplasmic dynein 1 heavy chain 1 OS=Homo sapiens OX=9606 GN=DYNC1H1 PE=1 SV=5 4.25 2641.1 - 256246 - - - 2.5467 - 3.316 0.571 - 334.2 1 2 1 0.0051 18 0 0 0 3.19E+06 2.93E+06 - - - 7.8897 1 221125_WJC_METTL3_EV_vs_WT_F08.14860.14860.3 5.98E-15 21/100 A.K[136.11]LVQDVANNTNEEAGDGTTTATVLAR[166.11].S "sp|P10809|CH60_HUMAN,tr|C9JL25|C9JL25_HUMAN,tr|A0A7I2V2X6|A0A7I2V2X6_HUMAN,tr|A0A7I2YQK6|A0A7I2YQK6_HUMAN,tr|A0A7I2V599|A0A7I2V599_HUMAN,tr|E7EXB4|E7EXB4_HUMAN,tr|A0A7I2YQ71|A0A7I2YQ71_HUMAN,tr|E7ESH4|E7ESH4_HUMAN,tr|A0A7I2V5M1|A0A7I2V5M1_HUMAN,tr|A0A7I2V5K3|A0A7I2V5K3_HUMAN,tr|A0A7I2V369|A0A7I2V369_HUMAN" 11 2705.3587 0.51 118211 14860 3 2705.365862 902.7935 "60 kDa heat shock protein, mitochondrial OS=Homo sapiens OX=9606 GN=HSPD1 PE=1 SV=2" 4.32 2641.2 - 246366 - - - 2.6525 - 4.107 0.765 - 537.5 1 1 0 0.0072 26 0 0 0 1.15E+06 2.26E+06 - - - 10.3171 1 221125_WJC_METTL3_EV_vs_WT_F08.14862.14862.3 1.58E-05 18/100 A.KLVQDVANNTNEEAGDGTTTATVLAR.S "sp|P10809|CH60_HUMAN,tr|C9JL25|C9JL25_HUMAN,tr|A0A7I2V2X6|A0A7I2V2X6_HUMAN,tr|A0A7I2YQK6|A0A7I2YQK6_HUMAN,tr|A0A7I2V599|A0A7I2V599_HUMAN,tr|E7EXB4|E7EXB4_HUMAN,tr|A0A7I2YQ71|A0A7I2YQ71_HUMAN,tr|E7ESH4|E7ESH4_HUMAN,tr|A0A7I2V5M1|A0A7I2V5M1_HUMAN,tr|A0A7I2V5K3|A0A7I2V5K3_HUMAN,tr|A0A7I2V369|A0A7I2V369_HUMAN" 11 2687.3362 0.51 118213 14862 3 2687.340139 896.786 "60 kDa heat shock protein, mitochondrial OS=Homo sapiens OX=9606 GN=HSPD1 PE=1 SV=2" 4.32 2641.5 - 174376 - - - 1.4598 - 3.704 0.656 - 321.3 1 1 0 0.0039 26 0 0 0 1.15E+06 2.26E+06 - - - 8.8652 0.9986 221125_WJC_METTL3_EV_vs_WT_F08.14867.14867.4 0.0728 15/84 R.STSHK[136.11]PDEIYGMIER[166.11].L sp|Q86U44|MTA70_HUMAN 1 1779.8581 -1 118217 14867 4 1779.862687 445.9718 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 5.42 2642.1 - 1.88E+06 - - - 2.603 - 2.473 0.314 - 165.8 1 2 0 0.0046 15 0 0 0 0.00E+00 0.00E+00 - - - 2.2817 1 221125_WJC_METTL3_EV_vs_WT_F08.14871.14871.3 3.58E-11 18/76 R.ETDC[160.03]GVHINAGPEIGVASTK[136.11].A "sp|Q06210|GFPT1_HUMAN,sp|O94808|GFPT2_HUMAN,tr|A0A6I8PRN4|A0A6I8PRN4_HUMAN,tr|A0A6I8PTT9|A0A6I8PTT9_HUMAN" 4 2061.9881 1.17 118220 14871 3 2061.991848 688.3366 Glutamine--fructose-6-phosphate aminotransferase [isomerizing] 1 OS=Homo sapiens OX=9606 GN=GFPT1 PE=1 SV=3 4.65 2642.5 - 1.47E+06 - - - 1.8327 - 3.364 0.663 - 330.4 1 2 0 0.0038 20 0 0 0 3.44E+07 2.93E+07 - - - 8.8738 0.9999 221125_WJC_METTL3_EV_vs_WT_F08.14872.14872.4 2.74E-07 13/114 K.NVIIWGNHSSTQYPDVNHAK.V "sp|P40925|MDHC_HUMAN,tr|C9JF79|C9JF79_HUMAN,tr|A0A5K1VW95|A0A5K1VW95_HUMAN,tr|B8ZZ51|B8ZZ51_HUMAN,tr|B9A041|B9A041_HUMAN" 5 2279.1083 0.75 118221 14872 4 2279.114282 570.7844 "Malate dehydrogenase, cytoplasmic OS=Homo sapiens OX=9606 GN=MDH1 PE=1 SV=4" 6.92 2642.6 - 850108 - - - 2.612 - 2.965 0.539 - 74.6 1 2 0 0.006 20 0 0 0 1.09E+07 1.44E+07 - - - 4.2792 0.9999 221125_WJC_METTL3_EV_vs_WT_F08.14874.14874.3 7.34E-06 19/68 K.SQPNLDTC[160.03]AFHEQPELQK.K "sp|P01037|CYTN_HUMAN,sp|P09228|CYTT_HUMAN,sp|P01036|CYTS_HUMAN" 3 2140.9848 41.2 118223 14874 3 2140.990978 714.6689 Cystatin-SN OS=Homo sapiens OX=9606 GN=CST1 PE=1 SV=3 4.65 2642.8 - 623345 - - - 2.9005 - 3.702 0.508 - 454 1 2 0 0.0062 18 0 0 0 3.57E+07 8.67E+05 - - - 7.4612 1 221125_WJC_METTL3_EV_vs_WT_F08.14875.14875.3 7.67E-13 19/100 A.K[136.11]LVQDVANNTNEEAGDGTTTATVLAR.S "sp|P10809|CH60_HUMAN,tr|C9JL25|C9JL25_HUMAN,tr|A0A7I2V2X6|A0A7I2V2X6_HUMAN,tr|A0A7I2YQK6|A0A7I2YQK6_HUMAN,tr|A0A7I2V599|A0A7I2V599_HUMAN,tr|E7EXB4|E7EXB4_HUMAN,tr|A0A7I2YQ71|A0A7I2YQ71_HUMAN,tr|E7ESH4|E7ESH4_HUMAN,tr|A0A7I2V5M1|A0A7I2V5M1_HUMAN,tr|A0A7I2V5K3|A0A7I2V5K3_HUMAN,tr|A0A7I2V369|A0A7I2V369_HUMAN" 11 2695.3504 - 118224 14875 3 2695.358409 899.4574 "60 kDa heat shock protein, mitochondrial OS=Homo sapiens OX=9606 GN=HSPD1 PE=1 SV=2" 4.32 2643 - 398242 - - - 2.9655 - 4.095 0.736 - 398.9 1 1 0 0.008 26 0 0 0 - - - - - 9.9868 1 221125_WJC_METTL3_EV_vs_WT_F08.14876.14876.3 1.47E-07 15/68 K.HSNLITVPIQDDSNSGAR[166.11].E "sp|Q75N03|HAKAI_HUMAN,tr|C9J2P9|C9J2P9_HUMAN" 2 1932.9529 0.51 118225 14876 3 1932.956966 645.3249 E3 ubiquitin-protein ligase Hakai OS=Homo sapiens OX=9606 GN=CBLL1 PE=1 SV=1 5.21 2643.1 - 375583 - - - 2.1102 - 2.853 0.561 - 272.2 1 2 0 0.0041 18 0 0 0 5.84E+06 1.15E+07 - - - 7.404 1 221125_WJC_METTL3_EV_vs_WT_F08.14878.14878.4 3.79E-09 18/84 R.KEYEQELSDDLHVER.Y "sp|Q7Z7F7|RM55_HUMAN,tr|X6R631|X6R631_HUMAN" 2 1888.8803 1.97 118227 14878 4 1888.884509 473.2273 "39S ribosomal protein L55, mitochondrial OS=Homo sapiens OX=9606 GN=MRPL55 PE=1 SV=1" 4.35 2643.4 - 247037 - - - 2.2357 - 3.608 0.552 - 418.6 1 2 0 0.0042 15 0 0 0 4.67E+06 2.36E+06 - - - 4.4886 0.9949 221125_WJC_METTL3_EV_vs_WT_F08.14880.14880.3 5.89E-05 Dec-68 K.GKEDEGEEAASPMLQIQR.D "sp|Q14204|DYHC1_HUMAN,tr|A0A7P0T8N2|A0A7P0T8N2_HUMAN,tr|A0A7P0T9C4|A0A7P0T9C4_HUMAN,tr|A0A7P0TBJ7|A0A7P0TBJ7_HUMAN,tr|A0A804HHY6|A0A804HHY6_HUMAN,tr|A0A7P0T9K2|A0A7P0T9K2_HUMAN,tr|A0A7P0TB64|A0A7P0TB64_HUMAN,tr|A0A2R8Y706|A0A2R8Y706_HUMAN,tr|A0A7P0T916|A0A7P0T916_HUMAN,tr|A0A7P0TB75|A0A7P0TB75_HUMAN,tr|A0A7P0T8W5|A0A7P0T8W5_HUMAN,tr|A0A7P0TAF3|A0A7P0TAF3_HUMAN,tr|A0A7P0T9F1|A0A7P0T9F1_HUMAN,tr|A0A7P0TAW9|A0A7P0TAW9_HUMAN,tr|A0A2R8YGC7|A0A2R8YGC7_HUMAN,tr|A0A7P0TA13|A0A7P0TA13_HUMAN,tr|A0A7P0TAV5|A0A7P0TAV5_HUMAN,tr|A0A7P0T7V5|A0A7P0T7V5_HUMAN,tr|A0A7P0T9R4|A0A7P0T9R4_HUMAN,tr|A0A2R8Y5T0|A0A2R8Y5T0_HUMAN,tr|A0A7P0T990|A0A7P0T990_HUMAN,tr|A0A7P0T942|A0A7P0T942_HUMAN,tr|A0A2R8YFZ7|A0A2R8YFZ7_HUMAN,tr|A0A7P0T825|A0A7P0T825_HUMAN,tr|A0A2R8Y6H2|A0A2R8Y6H2_HUMAN,tr|A0A7P0TAM4|A0A7P0TAM4_HUMAN" 26 1986.9317 0.53 118229 14880 3 1986.943558 663.3178 Cytoplasmic dynein 1 heavy chain 1 OS=Homo sapiens OX=9606 GN=DYNC1H1 PE=1 SV=5 4.25 2643.6 - 235074 - - - 5.9831 - 2.457 0.499 - 148.2 1 2 1 0.0119 18 0 0 0 3.97E+06 7.44E+06 - - - 6.3385 0.9983 221125_WJC_METTL3_EV_vs_WT_F08.14881.14881.3 0.00163 Nov-40 K.IWHHTFYNELR[166.11].V "sp|Q6S8J3|POTEE_HUMAN,sp|P63261|ACTG_HUMAN,sp|P68133|ACTS_HUMAN,sp|Q9BYX7|ACTBM_HUMAN,sp|P68032|ACTC_HUMAN,sp|P60709|ACTB_HUMAN,sp|A5A3E0|POTEF_HUMAN,sp|P0CG38|POTEI_HUMAN,sp|P0CG39|POTEJ_HUMAN,tr|A0A804GS07|A0A804GS07_HUMAN,tr|I3L3I0|I3L3I0_HUMAN,tr|G5E9R0|G5E9R0_HUMAN,tr|E7EVS6|E7EVS6_HUMAN,tr|A0A6Q8PFE4|A0A6Q8PFE4_HUMAN,tr|J3KT65|J3KT65_HUMAN,tr|I3L3R2|I3L3R2_HUMAN,tr|K7EM38|K7EM38_HUMAN,tr|A0A6Q8PH58|A0A6Q8PH58_HUMAN,tr|I3L1U9|I3L1U9_HUMAN,tr|A0A804HKV3|A0A804HKV3_HUMAN,tr|A0A2R8Y793|A0A2R8Y793_HUMAN,tr|I3L4N8|I3L4N8_HUMAN,tr|C9JUM1|C9JUM1_HUMAN,tr|C9JZR7|C9JZR7_HUMAN,tr|A0A2R8YGF8|A0A2R8YGF8_HUMAN,tr|A6NL76|A6NL76_HUMAN" 26 1524.7502 0.76 118230 14881 3 1524.757624 509.2573 POTE ankyrin domain family member E OS=Homo sapiens OX=9606 GN=POTEE PE=2 SV=3 6.92 2643.7 - 178203 - - - 4.9005 - 2.019 0.409 - 171.6 1 2 0 0.0075 11 0 0 0 1.72E+07 2.25E+07 - - - 5.0938 0.9957 221125_WJC_METTL3_EV_vs_WT_F08.14887.14887.3 0.0059 Jun-40 K.IWHHTFYNELR.V "sp|Q6S8J3|POTEE_HUMAN,sp|P63261|ACTG_HUMAN,sp|P68133|ACTS_HUMAN,sp|Q9BYX7|ACTBM_HUMAN,sp|P68032|ACTC_HUMAN,sp|P60709|ACTB_HUMAN,sp|A5A3E0|POTEF_HUMAN,sp|P0CG38|POTEI_HUMAN,sp|P0CG39|POTEJ_HUMAN,tr|A0A804GS07|A0A804GS07_HUMAN,tr|I3L3I0|I3L3I0_HUMAN,tr|G5E9R0|G5E9R0_HUMAN,tr|E7EVS6|E7EVS6_HUMAN,tr|A0A6Q8PFE4|A0A6Q8PFE4_HUMAN,tr|J3KT65|J3KT65_HUMAN,tr|I3L3R2|I3L3R2_HUMAN,tr|K7EM38|K7EM38_HUMAN,tr|A0A6Q8PH58|A0A6Q8PH58_HUMAN,tr|I3L1U9|I3L1U9_HUMAN,tr|A0A804HKV3|A0A804HKV3_HUMAN,tr|A0A2R8Y793|A0A2R8Y793_HUMAN,tr|I3L4N8|I3L4N8_HUMAN,tr|C9JUM1|C9JUM1_HUMAN,tr|C9JZR7|C9JZR7_HUMAN,tr|A0A2R8YGF8|A0A2R8YGF8_HUMAN,tr|A6NL76|A6NL76_HUMAN" 26 1514.7419 0.76 118235 14887 3 1514.745426 505.9212 POTE ankyrin domain family member E OS=Homo sapiens OX=9606 GN=POTEE PE=2 SV=3 6.92 2644.6 - 261581 - - - 2.3397 - 1.528 0.284 - 50.6 1 2 0 0.0035 11 0 0 0 1.70E+07 2.23E+07 - - - 2.9097 0.9997 221125_WJC_METTL3_EV_vs_WT_F08.14890.14890.4 1.03E-06 13/108 R.GTHELTNPGIAEVTIR[166.11]PDR[166.11].K sp|Q9BYB4|GNB1L_HUMAN 1 2095.0925 0.41 118238 14890 4 2095.101284 524.7804 Guanine nucleotide-binding protein subunit beta-like protein 1 OS=Homo sapiens OX=9606 GN=GNB1L PE=1 SV=2 5.45 2645 - 216936 - - - 4.1898 - 3.222 0.48 - 105.5 1 2 0 0.0088 19 0 0 0 4.03E+06 9.95E+06 - - - 3.7973 0.9996 221125_WJC_METTL3_EV_vs_WT_F08.14893.14893.3 0.000104 14/64 K.QQTDIAVNWAGGLHHAK.K "sp|Q13547|HDAC1_HUMAN,tr|Q5TEE2|Q5TEE2_HUMAN" 2 1844.9282 1.41 118240 14893 3 1844.934191 615.9833 Histone deacetylase 1 OS=Homo sapiens OX=9606 GN=HDAC1 PE=1 SV=1 6.92 2645.4 - 816519 - - - 3.2587 - 2.301 0.416 - 181.7 1 2 0 0.006 17 0 0 0 2.50E+07 1.78E+07 - - - 5.2816 1 221125_WJC_METTL3_EV_vs_WT_F08.14897.14897.4 3.52E-07 18/84 R.K[136.11]EYEQELSDDLHVER[166.11].Y "sp|Q7Z7F7|RM55_HUMAN,tr|X6R631|X6R631_HUMAN" 2 1906.9028 2.15 118244 14897 4 1906.907094 477.733 "39S ribosomal protein L55, mitochondrial OS=Homo sapiens OX=9606 GN=MRPL55 PE=1 SV=1" 4.35 2645.9 - 323459 - - - 2.2749 - 3.927 0.593 - 512.2 1 2 0 0.0043 15 0 0 0 4.48E+06 2.09E+06 - - - 4.8757 1 221125_WJC_METTL3_EV_vs_WT_F08.14898.14898.3 2.33E-07 15/64 K.STSTQGLEHDLDDVNAR[166.11].W "sp|Q03001|DYST_HUMAN,tr|A0A0U1RQJ2|A0A0U1RQJ2_HUMAN,tr|E9PHM6|E9PHM6_HUMAN,tr|F8W9J4|F8W9J4_HUMAN,tr|A0A7P0T890|A0A7P0T890_HUMAN,tr|F6QMI7|F6QMI7_HUMAN" 6 1866.8583 3.35 118245 14898 3 1866.855752 623.2934 Dystonin OS=Homo sapiens OX=9606 GN=DST PE=1 SV=4 4.22 2646 - 222532 - - - -1.3745 - 3.028 0.611 - 371.7 1 2 0 -0.0026 17 0 0 0 6.35E+06 1.89E+06 - - - 8.1502 1 221125_WJC_METTL3_EV_vs_WT_F08.14899.14899.3 5.59E-07 17/56 R.KEYEQELSDDLHVER.Y "sp|Q7Z7F7|RM55_HUMAN,tr|X6R631|X6R631_HUMAN" 2 1888.8803 1.18 118246 14899 3 1888.88441 630.634 "39S ribosomal protein L55, mitochondrial OS=Homo sapiens OX=9606 GN=MRPL55 PE=1 SV=1" 4.35 2646.1 - 203162 - - - 2.1833 - 3.598 0.536 - 504 1 2 0 0.0041 15 0 0 0 2.18E+06 1.86E+06 - - - 7.8557 1 221125_WJC_METTL3_EV_vs_WT_F08.14902.14902.2 3.39E-09 13/30 R.HDSEQDNSDNNTIFVQ.G sp|P35637|FUS_HUMAN 1 1861.7715 - 118249 14902 2 1861.769549 931.893 RNA-binding protein FUS OS=Homo sapiens OX=9606 GN=FUS PE=1 SV=1 3.84 2646.5 - 125039 - - - -1.0286 - 2.88 0.745 - 352.3 1 1 0 -0.0019 16 0 0 0 - - - - - 7.1436 0.9996 221125_WJC_METTL3_EV_vs_WT_F08.14907.14907.3 5.24E-05 13/48 K.ELHINLIPNKQDR.T "sp|P07900|HS90A_HUMAN,tr|G3V2J8|G3V2J8_HUMAN" 2 1588.8685 0.65 118252 14907 3 1588.872476 530.6301 Heat shock protein HSP 90-alpha OS=Homo sapiens OX=9606 GN=HSP90AA1 PE=1 SV=5 6.85 2647.2 - 890099 - - - 2.4779 - 2.609 0.485 - 242.4 1 2 1 0.0039 13 0 0 0 1.85E+07 2.87E+07 - - - 6.5462 1 221125_WJC_METTL3_EV_vs_WT_F08.14914.14914.3 1.27E-08 17/68 K.HSNLITVPIQDDSNSGAR.E "sp|Q75N03|HAKAI_HUMAN,tr|C9J2P9|C9J2P9_HUMAN" 2 1922.9446 0.46 118259 14914 3 1922.94979 641.9888 E3 ubiquitin-protein ligase Hakai OS=Homo sapiens OX=9606 GN=CBLL1 PE=1 SV=1 5.21 2648.1 - 241852 - - - 2.6901 - 2.967 0.609 - 438.7 1 2 0 0.0052 18 0 0 0 5.33E+06 1.16E+07 - - - 8.0364 0.9988 221125_WJC_METTL3_EV_vs_WT_F08.14917.14917.3 1.93E-07 Nov-60 R.HDSEQDNSDNNTIFVQ.G sp|P35637|FUS_HUMAN 1 1861.7715 - 118260 14917 3 1861.773187 621.5978 RNA-binding protein FUS OS=Homo sapiens OX=9606 GN=FUS PE=1 SV=1 3.84 2648.6 - 382978 - - - 0.9255 - 2.391 0.654 - 121.4 1 1 0 0.0017 16 0 0 0 - - - - - 8.0677 1 221125_WJC_METTL3_EV_vs_WT_F08.14918.14918.4 4.66E-05 15/96 R.AIWSQPELAYEEHHAHR[166.11].V sp|Q8IYS1|P20D2_HUMAN 1 2082.9899 1.02 118261 14918 4 2082.98934 521.7548 Xaa-Arg dipeptidase OS=Homo sapiens OX=9606 GN=PM20D2 PE=1 SV=2 5.76 2648.7 - 400116 - - - -0.289 - 3.149 0.508 - 233.1 1 2 0 -0.0006 17 0 0 0 8.25E+06 8.13E+06 - - - 4.0457 1 221125_WJC_METTL3_EV_vs_WT_F08.14923.14923.3 1.67E-12 18/92 R.APSTSPSFEGTQETYTVAHEENVR.F sp|Q9BUT9|MCRI2_HUMAN 1 2636.1991 1.11 118266 14923 3 2636.198423 879.7403 MAPK regulated corepressor interacting protein 2 OS=Homo sapiens OX=9606 GN=MCRIP2 PE=1 SV=2 4.48 2649.3 - 217856 - - - -0.2394 - 3.676 0.652 - 366.1 1 2 0 -0.0006 24 0 0 0 6.28E+06 5.68E+06 - - - 8.8326 0.9983 221125_WJC_METTL3_EV_vs_WT_F08.14931.14931.4 0.00414 8/114 K.NVIIWGNHSSTQYPDVNHAK[136.11].V "sp|P40925|MDHC_HUMAN,tr|C9JF79|C9JF79_HUMAN,tr|A0A5K1VW95|A0A5K1VW95_HUMAN,tr|B8ZZ51|B8ZZ51_HUMAN,tr|B9A041|B9A041_HUMAN" 5 2287.1225 0.98 118271 14931 4 2287.126537 572.7879 "Malate dehydrogenase, cytoplasmic OS=Homo sapiens OX=9606 GN=MDH1 PE=1 SV=4" 6.92 2650.4 - 411838 - - - 1.7524 - 2.094 0.313 - 32.5 2 2 0 0.004 20 0 0 0 1.08E+07 1.11E+07 - - - 1.9669 0.9997 221125_WJC_METTL3_EV_vs_WT_F08.14933.14933.4 2.95E-05 Dec-96 K.EERGDEVMVELAENGKK.A "sp|P35580|MYH10_HUMAN,tr|E7ERA5|E7ERA5_HUMAN" 2 1931.9259 1.09 118273 14933 4 1931.929764 483.9887 Myosin-10 OS=Homo sapiens OX=9606 GN=MYH10 PE=1 SV=3 4.42 2650.6 - 203818 - - - 2.0229 - 2.175 0.476 - 132 1 2 1 0.0039 17 0 0 0 4.07E+06 3.72E+06 - - - 3.6378 1 221125_WJC_METTL3_EV_vs_WT_F08.14939.14939.3 2.63E-06 14/48 R.AQSDIEHLFQHNR.K "sp|Q8TCG1|CIP2A_HUMAN,tr|A0A087X211|A0A087X211_HUMAN" 2 1593.7648 1.46 118277 14939 3 1593.766822 532.2622 Protein CIP2A OS=Homo sapiens OX=9606 GN=CIP2A PE=1 SV=2 6 2651.4 - 710723 - - - 1.2674 - 2.705 0.494 - 375.5 1 2 0 0.002 13 0 0 0 1.19E+07 8.12E+06 - - - 6.7451 0.9999 221125_WJC_METTL3_EV_vs_WT_F08.14949.14949.4 4.43E-06 17/72 R.AQSDIEHLFQHNR.K "sp|Q8TCG1|CIP2A_HUMAN,tr|A0A087X211|A0A087X211_HUMAN" 2 1593.7648 1.42 118285 14949 4 1593.767653 399.4485 Protein CIP2A OS=Homo sapiens OX=9606 GN=CIP2A PE=1 SV=2 6 2652.7 - 970953 - - - 1.7888 - 2.882 0.442 - 330 1 2 0 0.0029 13 0 0 0 1.40E+07 9.92E+06 - - - 3.4648 0.9998 221125_WJC_METTL3_EV_vs_WT_F08.14969.14969.4 1.97E-07 17/144 R.VTEGTIR[166.11]EEQEYEEEVEEEPR[166.11]PAAK[136.11].V "sp|O43491|E41L2_HUMAN,tr|Q6R5J7|Q6R5J7_HUMAN,tr|E9PHY5|E9PHY5_HUMAN,tr|E9PMV8|E9PMV8_HUMAN,tr|H0Y5B0|H0Y5B0_HUMAN,tr|E9PK52|E9PK52_HUMAN" 6 2974.4038 0.99 118298 14969 4 2974.407848 744.6082 Band 4.1-like protein 2 OS=Homo sapiens OX=9606 GN=EPB41L2 PE=1 SV=1 4.12 2655.4 - 382460 - - - 1.3626 - 2.797 0.467 - 182.6 1 2 1 0.0041 25 0 0 0 7.28E+06 7.36E+06 - - - 3.6168 0.9999 221125_WJC_METTL3_EV_vs_WT_F08.14971.14971.4 2.75E-08 18/96 R.AIWSQPELAYEEHHAHR.V sp|Q8IYS1|P20D2_HUMAN 1 2072.9817 1.01 118300 14971 4 2072.987194 519.2527 Xaa-Arg dipeptidase OS=Homo sapiens OX=9606 GN=PM20D2 PE=1 SV=2 5.76 2655.7 - 588739 - - - 2.6638 - 2.869 0.479 - 205.7 1 2 0 0.0055 17 0 0 0 8.25E+06 8.13E+06 - - - 3.7596 0.9429 221125_WJC_METTL3_EV_vs_WT_F08.14974.14974.4 0.0485 Sep-84 K.MKDTDSEEEIREAFR.V "sp|P0DP25|CALM3_HUMAN,sp|P0DP23|CALM1_HUMAN,sp|P0DP24|CALM2_HUMAN,tr|G3V361|G3V361_HUMAN,tr|A0A590UJI2|A0A590UJI2_HUMAN,tr|Q96HY3|Q96HY3_HUMAN,tr|A0A590UJC0|A0A590UJC0_HUMAN,tr|G3V226|G3V226_HUMAN,tr|E7EMB3|E7EMB3_HUMAN" 9 1854.8418 0.9 118303 14974 4 1854.845337 464.7177 Calmodulin-3 OS=Homo sapiens OX=9606 GN=CALM3 PE=1 SV=1 4.36 2656.1 - 144286 - - - 1.9112 - 1.301 0.212 - 74.7 1 2 2 0.0035 15 0 0 0 1.03E+07 1.14E+07 - - - 1.1644 0.9962 221125_WJC_METTL3_EV_vs_WT_F08.14975.14975.3 0.0222 Sep-68 R.ALQDLENAASGDAAVHQR[166.11].L "sp|Q96P16|RPR1A_HUMAN,tr|A0A0C4DGQ6|A0A0C4DGQ6_HUMAN,tr|K7EP82|K7EP82_HUMAN" 3 1874.911 2.4 118304 14975 3 1874.91847 625.9776 Regulation of nuclear pre-mRNA domain-containing protein 1A OS=Homo sapiens OX=9606 GN=RPRD1A PE=1 SV=1 4.54 2656.2 - 119013 - - - 3.9719 - 1.802 0.344 - 100.9 1 2 0 0.0074 18 0 0 0 2.10E+06 8.74E+05 - - - 3.8396 1 221125_WJC_METTL3_EV_vs_WT_F08.14981.14981.3 1.35E-10 24/64 R.R[166.11]EEMEQLFHDDQGGVTR[166.11].W "sp|Q15643|TRIPB_HUMAN,tr|H0YJ97|H0YJ97_HUMAN" 2 2065.939 1.12 118308 14981 3 2065.941299 689.6536 Thyroid receptor-interacting protein 11 OS=Homo sapiens OX=9606 GN=TRIP11 PE=1 SV=3 4.5 2657 - 379973 - - - 1.0925 - 4.167 0.647 - 1044.9 1 2 0 0.0023 17 0 0 0 1.41E+07 1.26E+07 - - - 9.3583 1 221125_WJC_METTL3_EV_vs_WT_F08.14982.14982.4 1.17E-11 16/96 R.REEMEQLFHDDQGGVTR.W "sp|Q15643|TRIPB_HUMAN,tr|H0YJ97|H0YJ97_HUMAN" 2 2045.9225 1.31 118309 14982 4 2045.92662 512.4879 Thyroid receptor-interacting protein 11 OS=Homo sapiens OX=9606 GN=TRIP11 PE=1 SV=3 4.5 2657.1 - 447474 - - - 2.0128 - 3.306 0.632 - 257.5 1 2 0 0.0041 17 0 0 0 1.31E+07 1.00E+07 - - - 5.1409 1 221125_WJC_METTL3_EV_vs_WT_F08.14987.14987.4 4.09E-06 22/96 R.R[166.11]EEMEQLFHDDQGGVTR[166.11].W "sp|Q15643|TRIPB_HUMAN,tr|H0YJ97|H0YJ97_HUMAN" 2 2065.939 1.31 118312 14987 4 2065.945156 517.492 Thyroid receptor-interacting protein 11 OS=Homo sapiens OX=9606 GN=TRIP11 PE=1 SV=3 4.5 2657.8 - 569081 - - - 2.9594 - 3.764 0.583 - 540.3 1 2 0 0.0061 17 0 0 0 1.29E+07 9.83E+06 - - - 4.7589 0.9995 221125_WJC_METTL3_EV_vs_WT_F08.14989.14989.3 0.00212 Dec-68 R.ALQDLENAASGDAAVHQR.L "sp|Q96P16|RPR1A_HUMAN,tr|A0A0C4DGQ6|A0A0C4DGQ6_HUMAN,tr|K7EP82|K7EP82_HUMAN" 3 1864.9028 2.4 118314 14989 3 1864.908605 622.6415 Regulation of nuclear pre-mRNA domain-containing protein 1A OS=Homo sapiens OX=9606 GN=RPRD1A PE=1 SV=1 4.54 2658.1 - 181884 - - - 3.138 - 2.743 0.366 - 197.6 1 2 0 0.0059 18 0 0 0 2.10E+06 8.74E+05 - - - 5.1316 0.7916 221125_WJC_METTL3_EV_vs_WT_F08.14996.14996.3 2.32E-05 15/68 R.GKVEIDQQQLTQQQLNGN.- "sp|Q8IWS0|PHF6_HUMAN,tr|A0A0D9SGE8|A0A0D9SGE8_HUMAN" 2 2040.0236 2.18 118319 14996 3 2041.013513 681.0151 PHD finger protein 6 OS=Homo sapiens OX=9606 GN=PHF6 PE=1 SV=1 4.37 2659 - 710788 - - - 485.2478 - 3.046 0.457 - 258.6 1 2 1 0.9899 18 0 0 0 5.27E+06 2.42E+06 - - - 6.1344 0.9995 221125_WJC_METTL3_EV_vs_WT_F08.14998.14998.3 2.95E-05 13/56 K.MK[136.11]DTDSEEEIR[166.11]EAFR[166.11].V "sp|P0DP25|CALM3_HUMAN,sp|P0DP23|CALM1_HUMAN,sp|P0DP24|CALM2_HUMAN,tr|G3V361|G3V361_HUMAN,tr|A0A590UJI2|A0A590UJI2_HUMAN,tr|Q96HY3|Q96HY3_HUMAN,tr|A0A590UJC0|A0A590UJC0_HUMAN,tr|G3V226|G3V226_HUMAN,tr|E7EMB3|E7EMB3_HUMAN" 9 1882.8725 0.99 118321 14998 3 1882.877277 628.6315 Calmodulin-3 OS=Homo sapiens OX=9606 GN=CALM3 PE=1 SV=1 4.36 2659.3 - 432795 - - - 2.5201 - 2.155 0.503 - 178.9 1 2 2 0.0047 15 0 0 0 8.28E+06 8.40E+06 - - - 6.1501 0.9993 221125_WJC_METTL3_EV_vs_WT_F08.15005.15005.4 0.00021 13/84 K.MK[136.11]DTDSEEEIR[166.11]EAFR[166.11].V "sp|P0DP25|CALM3_HUMAN,sp|P0DP23|CALM1_HUMAN,sp|P0DP24|CALM2_HUMAN,tr|G3V361|G3V361_HUMAN,tr|A0A590UJI2|A0A590UJI2_HUMAN,tr|Q96HY3|Q96HY3_HUMAN,tr|A0A590UJC0|A0A590UJC0_HUMAN,tr|G3V226|G3V226_HUMAN,tr|E7EMB3|E7EMB3_HUMAN" 9 1882.8725 0.91 118326 15005 4 1882.878041 471.7254 Calmodulin-3 OS=Homo sapiens OX=9606 GN=CALM3 PE=1 SV=1 4.36 2660.2 - 754456 - - - 2.9258 - 1.681 0.473 - 113.6 1 2 2 0.0055 15 0 0 0 1.01E+07 1.11E+07 - - - 3.5273 0.9829 221125_WJC_METTL3_EV_vs_WT_F08.15009.15009.3 0.105 Jul-92 K.TYTESYIARPDGDC[160.03]ASSLNGGNIK.G "sp|Q96GY0|ZC21A_HUMAN,tr|H0YAP0|H0YAP0_HUMAN" 2 2588.1813 0.5 118330 15009 3 2588.187872 863.7344 Zinc finger C2HC domain-containing protein 1A OS=Homo sapiens OX=9606 GN=ZC2HC1A PE=1 SV=2 4.56 2660.7 - 155567 - - - 2.5408 - 1.336 0.259 - 21.4 1 2 0 0.0066 24 0 0 0 8.97E+05 1.79E+06 - - - 2.0986 0.9998 221125_WJC_METTL3_EV_vs_WT_F08.15016.15016.4 0.000214 16/96 R.K[136.11]QHPYTFPGGSGTVFAR[166.11].N sp|Q10471|GALT2_HUMAN 1 1866.9496 2.04 118335 15016 4 1866.95317 467.7447 Polypeptide N-acetylgalactosaminyltransferase 2 OS=Homo sapiens OX=9606 GN=GALNT2 PE=1 SV=1 9.99 2661.6 - 295824 - - - 1.9192 - 2.369 0.418 - 180.3 1 2 0 0.0036 17 0 0 0 1.44E+07 7.04E+06 - - - 3.1627 0.9985 221125_WJC_METTL3_EV_vs_WT_F08.15021.15021.3 0.00761 Aug-36 K.QNRPIPQWIR.M "sp|P62891|RL39_HUMAN,sp|Q59GN2|R39L5_HUMAN" 2 1306.7258 0.43 118340 15021 3 1306.728572 436.5826 60S ribosomal protein L39 OS=Homo sapiens OX=9606 GN=RPL39 PE=1 SV=2 12 2662.2 - 195308 - - - 2.0923 - 1.627 0.321 - 118.1 1 2 0 0.0027 10 0 0 0 2.00E+06 4.64E+06 - - - 3.5396 1 221125_WJC_METTL3_EV_vs_WT_F08.15025.15025.4 5.26E-07 13/84 R.AHQLVMEGYNWC[160.03]HDR[166.11].N "sp|P67775|PP2AA_HUMAN,sp|P62714|PP2AB_HUMAN,tr|H0YC23|H0YC23_HUMAN" 3 1924.8336 1.01 118344 15025 4 1924.83407 482.2157 Serine\threonine-protein phosphatase 2A catalytic subunit alpha isoform OS=Homo sapiens OX=9606 GN=PPP2CA PE=1 SV=1 5.99 2662.7 - 140661 - - - 0.2229 - 2.669 0.66 - 162.4 1 2 0 0.0004 15 0 0 0 1.22E+06 1.21E+06 - - - 5.3218 0.9999 221125_WJC_METTL3_EV_vs_WT_F08.15026.15026.3 1.04E-05 Jul-92 K.TYTESYIAR[166.11]PDGDC[160.03]ASSLNGGNIK[136.11].G "sp|Q96GY0|ZC21A_HUMAN,tr|H0YAP0|H0YAP0_HUMAN" 2 2606.2038 0.5 118345 15026 3 2606.209095 869.7419 Zinc finger C2HC domain-containing protein 1A OS=Homo sapiens OX=9606 GN=ZC2HC1A PE=1 SV=2 4.56 2662.9 - 132350 - - - 2.0447 - 1.657 0.542 - 19.3 1 2 0 0.0053 24 0 0 0 8.97E+05 1.79E+06 - - - 5.7542 1 221125_WJC_METTL3_EV_vs_WT_F08.15030.15030.3 1.30E-13 27/84 K.PQVQLHVQSQTQPVSLANTQPR.G "sp|Q15942|ZYX_HUMAN,tr|H7C3D3|H7C3D3_HUMAN,tr|H0Y2Y8|H0Y2Y8_HUMAN" 3 2455.2932 3.74 118347 15030 3 2455.306369 819.4383 Zyxin OS=Homo sapiens OX=9606 GN=ZYX PE=1 SV=1 10.18 2663.5 - 628811 - - - 5.3757 - 5.173 0.695 - 702.2 1 1 0 0.0132 22 0 0 0 2.02E+07 5.40E+06 - - - 10.1813 0.9975 221125_WJC_METTL3_EV_vs_WT_F08.15031.15031.4 0.000119 15/108 K.LC[160.03]LTLHNNEGSYLAHTQGK[136.11].K "sp|Q15428|SF3A2_HUMAN,tr|K7EMT0|K7EMT0_HUMAN" 2 2163.0622 0.66 118348 15031 4 2163.074759 541.7728 Splicing factor 3A subunit 2 OS=Homo sapiens OX=9606 GN=SF3A2 PE=1 SV=2 6.91 2663.6 - 437852 - - - 5.789 - 3.064 0.407 - 187.1 1 2 0 0.0125 19 0 0 0 3.23E+06 4.89E+06 - - - 3.1438 0.9996 221125_WJC_METTL3_EV_vs_WT_F08.15034.15034.3 8.95E-09 18/64 R.K[136.11]QHPYTFPGGSGTVFAR[166.11].N sp|Q10471|GALT2_HUMAN 1 1866.9496 1.56 118351 15034 3 1866.960632 623.3238 Polypeptide N-acetylgalactosaminyltransferase 2 OS=Homo sapiens OX=9606 GN=GALNT2 PE=1 SV=1 9.99 2664 - 408036 - - - 5.9161 - 3.22 0.563 - 445.1 1 2 0 0.011 17 0 0 0 8.76E+06 5.61E+06 - - - 7.768 0.9964 221125_WJC_METTL3_EV_vs_WT_F08.15035.15035.4 0.000124 Sep-84 K.DKFNEC[160.03]GHVLYADIK.M "sp|P52272|HNRPM_HUMAN,tr|A0A087X0X3|A0A087X0X3_HUMAN" 2 1807.8563 1.71 118352 15035 4 1807.862142 452.9714 Heterogeneous nuclear ribonucleoprotein M OS=Homo sapiens OX=9606 GN=HNRNPM PE=1 SV=3 5.38 2664.1 - 309525 - - - 3.2204 - 2.133 0.367 - 49.7 1 2 1 0.0058 15 0 0 0 1.27E+07 7.41E+06 - - - 2.6898 1 221125_WJC_METTL3_EV_vs_WT_F08.15044.15044.3 1.34E-11 20/56 R.STSHK[136.11]PDEIYGMIER[166.11].L sp|Q86U44|MTA70_HUMAN 1 1779.8581 0.01 118359 15044 3 1779.863003 594.2933 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 5.42 2665.2 - 2.63E+06 - - - 2.7806 - 3.871 0.57 - 473.4 1 2 0 0.0049 15 0 0 0 2.05E+06 1.59E+08 - - - 8.4254 1 221125_WJC_METTL3_EV_vs_WT_F08.15045.15045.3 4.90E-10 20/56 K.DKFNEC[160.03]GHVLYADIK.M "sp|P52272|HNRPM_HUMAN,tr|A0A087X0X3|A0A087X0X3_HUMAN" 2 1807.8563 1.81 118360 15045 3 1807.86289 603.626 Heterogeneous nuclear ribonucleoprotein M OS=Homo sapiens OX=9606 GN=HNRNPM PE=1 SV=3 5.38 2665.3 - 691264 - - - 3.6341 - 3.901 0.677 - 419 1 2 1 0.0066 15 0 0 0 1.29E+07 7.11E+06 - - - 9.638 0.9999 221125_WJC_METTL3_EV_vs_WT_F08.15046.15046.3 2.91E-05 17/64 R.KQHPYTFPGGSGTVFAR.N sp|Q10471|GALT2_HUMAN 1 1848.9271 1.57 118361 15046 3 1848.934208 617.3163 Polypeptide N-acetylgalactosaminyltransferase 2 OS=Homo sapiens OX=9606 GN=GALNT2 PE=1 SV=1 9.99 2665.4 - 588384 - - - 3.8352 - 3.61 0.561 - 381.9 1 2 0 0.0071 17 0 0 0 9.02E+06 5.76E+06 - - - 8.0357 0.9997 221125_WJC_METTL3_EV_vs_WT_F08.15047.15047.4 2.00E-06 14/84 K.DK[136.11]FNEC[160.03]GHVLYADIK[136.11].M "sp|P52272|HNRPM_HUMAN,tr|A0A087X0X3|A0A087X0X3_HUMAN" 2 1823.8847 1.74 118362 15047 4 1823.889342 456.9785 Heterogeneous nuclear ribonucleoprotein M OS=Homo sapiens OX=9606 GN=HNRNPM PE=1 SV=3 5.38 2665.6 - 525978 - - - 2.5342 - 2.815 0.499 - 151 1 2 1 0.0046 15 0 0 0 1.27E+07 7.29E+06 - - - 3.9383 1 221125_WJC_METTL3_EV_vs_WT_F08.15048.15048.3 1.63E-11 21/96 K.EGVILTNESAASTGQPDNDVTEGQR[166.11].A sp|Q08J23|NSUN2_HUMAN 1 2597.2081 1.08 118363 15048 3 2597.213616 866.7433 RNA cytosine C(5)-methyltransferase NSUN2 OS=Homo sapiens OX=9606 GN=NSUN2 PE=1 SV=2 3.83 2665.7 - 476123 - - - 2.1423 - 4.004 0.683 - 352.6 1 2 0 0.0056 25 0 0 0 1.50E+07 1.38E+07 - - - 9.3449 1 221125_WJC_METTL3_EV_vs_WT_F08.15050.15050.3 2.28E-09 17/56 K.DK[136.11]FNEC[160.03]GHVLYADIK[136.11].M "sp|P52272|HNRPM_HUMAN,tr|A0A087X0X3|A0A087X0X3_HUMAN" 2 1823.8847 1.81 118365 15050 3 1823.89241 608.9688 Heterogeneous nuclear ribonucleoprotein M OS=Homo sapiens OX=9606 GN=HNRNPM PE=1 SV=3 5.38 2665.9 - 427128 - - - 4.2163 - 3.234 0.622 - 262.1 1 2 1 0.0077 15 0 0 0 1.29E+07 7.11E+06 - - - 8.5352 0.9898 221125_WJC_METTL3_EV_vs_WT_F08.15051.15051.3 0.0121 Dec-56 K.MKDTDSEEEIREAFR.V "sp|P0DP25|CALM3_HUMAN,sp|P0DP23|CALM1_HUMAN,sp|P0DP24|CALM2_HUMAN,tr|G3V361|G3V361_HUMAN,tr|A0A590UJI2|A0A590UJI2_HUMAN,tr|Q96HY3|Q96HY3_HUMAN,tr|A0A590UJC0|A0A590UJC0_HUMAN,tr|G3V226|G3V226_HUMAN,tr|E7EMB3|E7EMB3_HUMAN" 9 1854.8418 0.88 118366 15051 3 1854.849399 619.2879 Calmodulin-3 OS=Homo sapiens OX=9606 GN=CALM3 PE=1 SV=1 4.36 2666.1 - 426815 - - - 4.1012 - 2.098 0.347 - 137.5 1 2 2 0.0076 15 0 0 0 7.46E+06 8.48E+06 - - - 4.3401 1 221125_WJC_METTL3_EV_vs_WT_F08.15052.15052.3 1.50E-11 30/84 K.PQVQLHVQSQTQPVSLANTQPR[166.11].G "sp|Q15942|ZYX_HUMAN,tr|H7C3D3|H7C3D3_HUMAN,tr|H0Y2Y8|H0Y2Y8_HUMAN" 3 2465.3014 3.74 118367 15052 3 2465.309195 822.7744 Zyxin OS=Homo sapiens OX=9606 GN=ZYX PE=1 SV=1 10.18 2666.2 - 424562 - - - 3.1457 - 5.453 0.695 - 940.3 1 1 0 0.0078 22 0 0 0 2.02E+07 5.40E+06 - - - 10.3077 0.9996 221125_WJC_METTL3_EV_vs_WT_F08.15053.15053.4 6.54E-08 14/120 R.IMGPNYTPGK[136.11]K[136.11]EDLYLK[136.11]PIQR[166.11].T sp|P13639|EF2_HUMAN 1 2494.3708 0.36 118368 15053 4 2494.379057 624.6 Elongation factor 2 OS=Homo sapiens OX=9606 GN=EEF2 PE=1 SV=4 9.4 2666.3 - 404077 - - - 3.3215 - 2.579 0.547 - 117.5 1 2 1 0.0083 21 0 0 0 1.39E+06 3.81E+06 - - - 4.298 0.9996 221125_WJC_METTL3_EV_vs_WT_F08.15056.15056.4 2.95E-06 Dec-96 R.SHGVLLEVQYSSSIHDR.E "sp|Q8WV92|MITD1_HUMAN,tr|B8ZZL5|B8ZZL5_HUMAN,tr|H7C3Q6|H7C3Q6_HUMAN" 3 1925.9595 1.41 118371 15056 4 1925.965396 482.4972 MIT domain-containing protein 1 OS=Homo sapiens OX=9606 GN=MITD1 PE=1 SV=1 5.94 2666.7 - 137388 - - - 3.0411 - 3.004 0.397 - 88.6 1 2 0 0.0059 17 0 0 0 7.16E+05 5.08E+05 - - - 3.0618 0.9999 221125_WJC_METTL3_EV_vs_WT_F08.15061.15061.3 5.59E-07 Oct-72 K.LC[160.03]LTLHNNEGSYLAHTQGK[136.11].K "sp|Q15428|SF3A2_HUMAN,tr|K7EMT0|K7EMT0_HUMAN" 2 2163.0622 0.64 118375 15061 3 2163.067536 722.028 Splicing factor 3A subunit 2 OS=Homo sapiens OX=9606 GN=SF3A2 PE=1 SV=2 6.91 2667.3 - 201981 - - - 2.4498 - 2.37 0.474 - 125.8 1 2 0 0.0053 19 0 0 0 1.11E+06 1.73E+06 - - - 5.9431 1 221125_WJC_METTL3_EV_vs_WT_F08.15062.15062.3 3.99E-10 25/76 R.QNQFYDTQVIKQENESGYER.R "sp|Q9BUJ2|HNRL1_HUMAN,tr|M0R0K8|M0R0K8_HUMAN,tr|M0QYZ0|M0QYZ0_HUMAN,tr|A0A0A0MRA5|A0A0A0MRA5_HUMAN,tr|M0QZV6|M0QZV6_HUMAN,tr|B7Z4B8|B7Z4B8_HUMAN,tr|M0R203|M0R203_HUMAN" 7 2475.1302 1.61 118376 15062 3 2475.137464 826.0507 Heterogeneous nuclear ribonucleoprotein U-like protein 1 OS=Homo sapiens OX=9606 GN=HNRNPUL1 PE=1 SV=2 4.41 2667.5 - 1.16E+06 - - - 2.9162 - 4.228 0.647 - 883 1 2 1 0.0072 20 0 0 0 3.11E+07 1.93E+07 - - - 9.2491 1 221125_WJC_METTL3_EV_vs_WT_F08.15063.15063.3 2.36E-09 19/64 R.REEMEQLFHDDQGGVTR.W "sp|Q15643|TRIPB_HUMAN,tr|H0YJ97|H0YJ97_HUMAN" 2 2045.9225 1.11 118377 15063 3 2045.929278 682.9814 Thyroid receptor-interacting protein 11 OS=Homo sapiens OX=9606 GN=TRIP11 PE=1 SV=3 4.5 2667.6 - 565928 - - - 3.312 - 3.238 0.626 - 515.1 1 2 0 0.0068 17 0 0 0 1.41E+07 1.27E+07 - - - 8.4857 1 221125_WJC_METTL3_EV_vs_WT_F08.15064.15064.3 5.32E-11 20/72 K.GDRSEDFGVNEDLADSDAR.A sp|P04083|ANXA1_HUMAN 1 2066.8777 224.08 118378 15064 3 2066.871332 689.9665 Annexin A1 OS=Homo sapiens OX=9606 GN=ANXA1 PE=1 SV=2 3.85 2667.7 - 562506 - - - -3.0907 - 3.634 0.676 - 582.5 1 2 1 -0.0064 19 0 0 0 1.11E+07 4.96E+04 - - - 9.2451 0.9987 221125_WJC_METTL3_EV_vs_WT_F08.15067.15067.4 7.79E-05 Nov-96 R.KQHPYTFPGGSGTVFAR.N sp|Q10471|GALT2_HUMAN 1 1848.9271 1.54 118381 15067 4 1848.934817 463.2391 Polypeptide N-acetylgalactosaminyltransferase 2 OS=Homo sapiens OX=9606 GN=GALNT2 PE=1 SV=1 9.99 2668.1 - 484732 - - - 4.1646 - 2.748 0.378 - 84 1 2 0 0.0077 17 0 0 0 1.03E+07 6.71E+06 - - - 2.865 0.9966 221125_WJC_METTL3_EV_vs_WT_F08.15070.15070.4 2.11E-06 14/108 R.AHPVFYQGTYSQALNDAK[136.11]R[166.11].E sp|Q96CS3|FAF2_HUMAN 1 2183.0879 1.42 118384 15070 4 2183.106038 546.7792 FAS-associated factor 2 OS=Homo sapiens OX=9606 GN=FAF2 PE=1 SV=2 8.55 2668.5 - 232601 - - - 8.3217 - 2.686 0.481 - 135.3 1 2 0 0.0182 19 0 0 0 1.48E+07 1.05E+07 - - - 3.7418 1 221125_WJC_METTL3_EV_vs_WT_F08.15079.15079.3 2.83E-09 25/76 R.QNQFYDTQVIK[136.11]QENESGYER[166.11].R "sp|Q9BUJ2|HNRL1_HUMAN,tr|M0R0K8|M0R0K8_HUMAN,tr|M0QYZ0|M0QYZ0_HUMAN,tr|A0A0A0MRA5|A0A0A0MRA5_HUMAN,tr|M0QZV6|M0QZV6_HUMAN,tr|B7Z4B8|B7Z4B8_HUMAN,tr|M0R203|M0R203_HUMAN" 7 2493.1527 1.61 118391 15079 3 2493.158062 832.0582 Heterogeneous nuclear ribonucleoprotein U-like protein 1 OS=Homo sapiens OX=9606 GN=HNRNPUL1 PE=1 SV=2 4.41 2669.7 - 2.20E+06 - - - 2.1443 - 4.652 0.654 - 929.5 1 2 1 0.0053 20 0 0 0 3.11E+07 1.93E+07 - - - 9.5595 1 221125_WJC_METTL3_EV_vs_WT_F08.15080.15080.2 1.14E-13 18/38 R.FSSC[160.03]GGGGGSFGAGGGFGSR.S sp|P04264|K2C1_HUMAN 1 1764.7274 999 118392 15080 2 1764.727494 883.371 "Keratin, type II cytoskeletal 1 OS=Homo sapiens OX=9606 GN=KRT1 PE=1 SV=6" 8.25 2669.8 - 676681 - - - 0.0357 - 3.894 0.774 - 943.8 1 2 0 0.0001 20 0 0 0 9.69E+06 0.00E+00 - - - 8.1 0.9997 221125_WJC_METTL3_EV_vs_WT_F08.15081.15081.4 2.29E-11 21/102 K.LLNTVEETTKDVSGLHSK.L "sp|P52732|KIF11_HUMAN,tr|A0A7I2YQY4|A0A7I2YQY4_HUMAN,tr|A0A7I2V3A9|A0A7I2V3A9_HUMAN" 3 1970.032 4.65 118393 15081 4 1970.039375 493.5153 Kinesin-like protein KIF11 OS=Homo sapiens OX=9606 GN=KIF11 PE=1 SV=2 5.45 2669.9 - 674429 - - - 3.7253 - 3.868 0.594 - 317.4 1 2 1 0.0073 18 0 0 0 3.07E+07 6.59E+06 - - - 4.8575 0.9998 221125_WJC_METTL3_EV_vs_WT_F08.15082.15082.4 7.17E-10 20/114 R.KPYPEDPAVYKPLSQEELQR.L sp|O95628|CNOT4_HUMAN 1 2386.2169 1.76 118394 15082 4 2386.227805 597.5615 CCR4-NOT transcription complex subunit 4 OS=Homo sapiens OX=9606 GN=CNOT4 PE=1 SV=3 4.87 2670.1 - 473379 - - - 4.5801 - 3.924 0.563 - 347.8 1 2 0 0.0109 20 0 0 0 2.18E+07 1.24E+07 - - - 4.5804 0.9999 221125_WJC_METTL3_EV_vs_WT_F08.15083.15083.3 2.75E-06 Dec-76 R.FSSC[160.03]GGGGGSFGAGGGFGSR.S sp|P04264|K2C1_HUMAN 1 1764.7274 72.17 118395 15083 3 1764.73413 589.2498 "Keratin, type II cytoskeletal 1 OS=Homo sapiens OX=9606 GN=KRT1 PE=1 SV=6" 8.25 2670.2 - 376491 - - - 3.7961 - 2.521 0.568 - 126.5 1 2 0 0.0067 20 0 0 0 4.68E+06 6.48E+04 - - - 7.114 1 221125_WJC_METTL3_EV_vs_WT_F08.15093.15093.3 5.78E-11 23/68 K.LLNTVEETTKDVSGLHSK.L "sp|P52732|KIF11_HUMAN,tr|A0A7I2YQY4|A0A7I2YQY4_HUMAN,tr|A0A7I2V3A9|A0A7I2V3A9_HUMAN" 3 1970.032 7.81 118403 15093 3 1970.040275 657.6846 Kinesin-like protein KIF11 OS=Homo sapiens OX=9606 GN=KIF11 PE=1 SV=2 5.45 2671.5 - 579941 - - - 4.1822 - 4.715 0.655 - 605.2 1 2 1 0.0082 18 0 0 0 1.36E+07 1.74E+06 - - - 9.7018 0.9999 221125_WJC_METTL3_EV_vs_WT_F08.15094.15094.3 3.29E-09 16/84 R.ELDAISTNEEEKEENEAESDVK.H "sp|P49642|PRI1_HUMAN,tr|A0A5F9ZHB6|A0A5F9ZHB6_HUMAN,tr|A0A3B3ITS8|A0A3B3ITS8_HUMAN" 3 2507.1035 0.74 118404 15094 3 2507.106336 836.7084 DNA primase small subunit OS=Homo sapiens OX=9606 GN=PRIM1 PE=1 SV=1 3.84 2671.6 - 355786 - - - 1.1384 - 3.236 0.631 - 256.9 1 2 1 0.0029 22 0 0 0 2.96E+06 3.98E+06 - - - 8.3584 1 221125_WJC_METTL3_EV_vs_WT_F08.15095.15095.3 2.70E-12 19/52 K.HEWQVNGLDDIKDR.S sp|Q9Y281|COF2_HUMAN 1 1723.8278 1.32 118405 15095 3 1723.833333 575.6165 Cofilin-2 OS=Homo sapiens OX=9606 GN=CFL2 PE=1 SV=1 4.66 2671.7 - 351652 - - - 3.2115 - 3.652 0.659 - 571 1 2 1 0.0055 14 0 0 0 7.37E+06 5.58E+06 - - - 9.3279 0.9996 221125_WJC_METTL3_EV_vs_WT_F08.15102.15102.4 0.0146 16/84 R.STSHK[136.11]PDEIYGMIER[166.11].L sp|Q86U44|MTA70_HUMAN 1 1779.8581 0.02 118411 15102 4 1779.863424 445.9718 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 5.42 2672.6 - 1.38E+06 - - - 3.0171 - 2.529 0.4 - 194 1 2 0 0.0054 15 0 0 0 1.52E+06 6.15E+07 - - - 3.0381 0.9986 221125_WJC_METTL3_EV_vs_WT_F08.15104.15104.4 7.39E-06 19/120 R.LTSTATKDPEGFVGHPVNAFK.L sp|P13674|P4HA1_HUMAN 1 2215.1273 1.15 118412 15104 4 2215.13695 554.7891 Prolyl 4-hydroxylase subunit alpha-1 OS=Homo sapiens OX=9606 GN=P4HA1 PE=1 SV=2 6.75 2673 - 736895 - - - 4.3415 - 2.991 0.478 - 174.1 1 2 1 0.0096 21 0 0 0 5.88E+06 5.13E+06 - - - 3.7461 0.9997 221125_WJC_METTL3_EV_vs_WT_F08.15106.15106.4 1.33E-10 15/132 R.YPNGPDYQLHNYGDHSSVSEQFR.D sp|P20719|HXA5_HUMAN 1 2709.1844 1.75 118414 15106 4 2709.195918 678.3034 Homeobox protein Hox-A5 OS=Homo sapiens OX=9606 GN=HOXA5 PE=1 SV=2 5.21 2673.2 - 543656 - - - 4.2489 - 3.269 0.481 - 110.8 1 2 0 0.0115 23 0 0 0 5.77E+06 3.30E+06 - - - 3.7932 0.9995 221125_WJC_METTL3_EV_vs_WT_F08.15107.15107.4 2.91E-05 14/102 K.LLNTVEETTK[136.11]DVSGLHSK[136.11].L "sp|P52732|KIF11_HUMAN,tr|A0A7I2YQY4|A0A7I2YQY4_HUMAN,tr|A0A7I2V3A9|A0A7I2V3A9_HUMAN" 3 1986.0604 4.67 118415 15107 4 1986.066621 497.5224 Kinesin-like protein KIF11 OS=Homo sapiens OX=9606 GN=KIF11 PE=1 SV=2 5.45 2673.4 - 438816 - - - 3.1142 - 2.993 0.491 - 108.7 1 2 1 0.0062 18 0 0 0 3.07E+07 6.57E+06 - - - 3.8735 1 221125_WJC_METTL3_EV_vs_WT_F08.15109.15109.3 1.01E-07 15/80 R.FSTQC[160.03]QYQGSYSSC[160.03]GPQFQSR.A sp|Q5T749|KPRP_HUMAN 1 2502.0329 999 118417 15109 3 2502.038562 835.0182 Keratinocyte proline-rich protein OS=Homo sapiens OX=9606 GN=KPRP PE=1 SV=1 8.05 2673.6 - 306368 - - - 2.2797 - 3.234 0.65 - 221.7 1 2 0 0.0057 21 0 0 0 3.32E+07 0.00E+00 - - - 8.5992 0.9996 221125_WJC_METTL3_EV_vs_WT_F08.15114.15114.3 1.70E-05 13/68 K.SQPNLDTC[160.03]AFHEQPELQK.K "sp|P01037|CYTN_HUMAN,sp|P09228|CYTT_HUMAN,sp|P01036|CYTS_HUMAN" 3 2140.9848 18.81 118421 15114 3 2140.99364 714.6689 Cystatin-SN OS=Homo sapiens OX=9606 GN=CST1 PE=1 SV=3 4.65 2674.2 - 224846 - - - 4.1439 - 2.713 0.442 - 173.6 1 2 0 0.0089 18 0 0 0 3.87E+07 2.06E+06 - - - 5.9507 1 221125_WJC_METTL3_EV_vs_WT_F08.15117.15117.2 1.90E-05 13/26 R.HDSEQDNSDNNTIF.V sp|P35637|FUS_HUMAN 1 1634.6445 - 118424 15117 2 1634.648444 818.3295 RNA-binding protein FUS OS=Homo sapiens OX=9606 GN=FUS PE=1 SV=1 3.84 2674.6 - 822300 - - - 2.4299 - 2.739 0.717 - 734.8 1 1 0 0.004 14 0 0 0 - - - - - 6.864 0.9999 221125_WJC_METTL3_EV_vs_WT_F08.15118.15118.4 2.68E-09 14/114 R.K[136.11]PYPEDPAVYK[136.11]PLSQEELQR[166.11].L sp|O95628|CNOT4_HUMAN 1 2412.2535 1.8 118425 15118 4 2412.26094 604.0707 CCR4-NOT transcription complex subunit 4 OS=Homo sapiens OX=9606 GN=CNOT4 PE=1 SV=3 4.87 2674.7 - 541911 - - - 3.0652 - 3.514 0.534 - 116.5 1 2 0 0.0074 20 0 0 0 2.23E+07 1.24E+07 - - - 4.292 0.9999 221125_WJC_METTL3_EV_vs_WT_F08.15119.15119.4 6.27E-06 12/132 R.YPNGPDYQLHNYGDHSSVSEQFR[166.11].D sp|P20719|HXA5_HUMAN 1 2719.1927 1.75 118426 15119 4 2719.203276 680.8054 Homeobox protein Hox-A5 OS=Homo sapiens OX=9606 GN=HOXA5 PE=1 SV=2 5.21 2674.9 - 283562 - - - 3.8978 - 2.451 0.546 - 84 1 2 0 0.0106 23 0 0 0 5.77E+06 3.30E+06 - - - 4.2659 0.9919 221125_WJC_METTL3_EV_vs_WT_F08.15120.15120.3 4.20E-05 7/104 R.LAALALASSENSSSTPEEC[160.03]EEMSEK[136.11]PK[136.11].K sp|O00567|NOP56_HUMAN 1 2910.3445 -1 118427 15120 3 2910.317288 971.1221 Nucleolar protein 56 OS=Homo sapiens OX=9606 GN=NOP56 PE=1 SV=4 4.21 2675 - 248684 - - - -9.3618 - 2.029 0.509 - 28.2 2 2 0 -0.0272 27 0 0 0 0.00E+00 0.00E+00 - - - 5.6958 1 221125_WJC_METTL3_EV_vs_WT_F08.15121.15121.3 6.00E-11 20/96 K.VQERPPSASSSSDMSLSEPPQPLAR.K sp|Q5VT06|CE350_HUMAN 1 2652.2813 2.05 118428 15121 3 2652.284824 885.1011 Centrosome-associated protein 350 OS=Homo sapiens OX=9606 GN=CEP350 PE=1 SV=1 4.68 2675.1 - 247221 - - - 1.3121 - 3.899 0.686 - 252.2 1 2 0 0.0035 25 0 0 0 1.02E+07 5.00E+06 - - - 9.3178 0.971 221125_WJC_METTL3_EV_vs_WT_F08.15123.15123.3 0.0427 Jun-80 R.LTSTATKDPEGFVGHPVNAFK.L sp|P13674|P4HA1_HUMAN 1 2215.1273 2.41 118430 15123 3 2215.130988 739.3831 Prolyl 4-hydroxylase subunit alpha-1 OS=Homo sapiens OX=9606 GN=P4HA1 PE=1 SV=2 6.75 2675.4 - 151598 - - - 1.65 - 1.663 0.233 - 28.9 1 2 1 0.0037 21 0 0 0 1.14E+06 4.72E+05 - - - 2.3561 1 221125_WJC_METTL3_EV_vs_WT_F08.15124.15124.3 3.06E-06 17/96 K.VQER[166.11]PPSASSSSDMSLSEPPQPLAR[166.11].K sp|Q5VT06|CE350_HUMAN 1 2672.2979 2.05 118431 15124 3 2672.30531 891.7732 Centrosome-associated protein 350 OS=Homo sapiens OX=9606 GN=CEP350 PE=1 SV=1 4.68 2675.5 - 120901 - - - 2.7789 - 2.918 0.627 - 151.1 1 2 0 0.0074 25 0 0 0 1.02E+07 5.00E+06 - - - 7.9921 0.9976 221125_WJC_METTL3_EV_vs_WT_F08.15128.15128.3 0.00636 21/72 R.ANNLHSGDNFQLNDSEIER.Q "sp|Q9BZF1|OSBL8_HUMAN,tr|F8VUA7|F8VUA7_HUMAN,tr|F8VQX7|F8VQX7_HUMAN" 3 2171.9832 0.43 118433 15128 3 2171.997911 725.0017 Oxysterol-binding protein-related protein 8 OS=Homo sapiens OX=9606 GN=OSBPL8 PE=1 SV=3 4.31 2676.1 - 579224 - - - 6.7786 - 3.307 0.406 - 447.2 1 2 0 0.0147 19 0 0 0 2.92E+06 6.76E+06 - - - 6.0009 0.996 221125_WJC_METTL3_EV_vs_WT_F08.15130.15130.2 0.103 16-Oct K.VGLQVVAVK.A "sp|P10809|CH60_HUMAN,tr|A0A7I2V2X6|A0A7I2V2X6_HUMAN,tr|A0A7I2YQK6|A0A7I2YQK6_HUMAN,tr|A0A7I2V599|A0A7I2V599_HUMAN,tr|A0A7I2V5M1|A0A7I2V5M1_HUMAN" 5 911.5804 1.31 118435 15130 2 911.583957 456.7975 "60 kDa heat shock protein, mitochondrial OS=Homo sapiens OX=9606 GN=HSPD1 PE=1 SV=2" 8.72 2676.3 - 269087 - - - 3.8987 - 1.979 0.286 - 235.2 1 2 0 0.0036 9 0 0 0 6.12E+06 4.68E+06 - - - 3.1271 0.9998 221125_WJC_METTL3_EV_vs_WT_F08.15131.15131.3 1.18E-08 17/76 R.KPYPEDPAVYKPLSQEELQR.L sp|O95628|CNOT4_HUMAN 1 2386.2169 1.95 118436 15131 3 2386.228916 796.4129 CCR4-NOT transcription complex subunit 4 OS=Homo sapiens OX=9606 GN=CNOT4 PE=1 SV=3 4.87 2676.5 - 249757 - - - 5.0456 - 3.312 0.582 - 179.4 1 2 0 0.012 20 0 0 0 4.98E+06 2.55E+06 - - - 7.9307 0.9999 221125_WJC_METTL3_EV_vs_WT_F08.15132.15132.3 8.87E-09 17/80 R.VVNTDHGSPEQLQIPVTDSGR.H sp|Q6IQ49|SDE2_HUMAN 1 2248.1084 1.89 118437 15132 3 2248.116765 750.3767 Replication stress response regulator SDE2 OS=Homo sapiens OX=9606 GN=SDE2 PE=1 SV=1 4.54 2676.6 - 227880 - - - 3.7262 - 3.14 0.587 - 215.9 1 2 0 0.0084 21 0 0 0 4.23E+07 2.24E+07 - - - 7.8254 0.996 221125_WJC_METTL3_EV_vs_WT_F08.15133.15133.4 0.000728 Oct-72 K.ELHINLIPNK[136.11]QDR[166.11].T "sp|P07900|HS90A_HUMAN,tr|G3V2J8|G3V2J8_HUMAN" 2 1606.891 0.74 118438 15133 4 1606.897303 402.73 Heat shock protein HSP 90-alpha OS=Homo sapiens OX=9606 GN=HSP90AA1 PE=1 SV=5 6.85 2676.7 - 137340 - - - 3.9169 - 1.73 0.4 - 72.5 1 2 1 0.0063 13 0 0 0 1.77E+06 2.40E+06 - - - 2.9091 0.9999 221125_WJC_METTL3_EV_vs_WT_F08.15135.15135.3 8.02E-07 Dec-76 R.K[136.11]PYPEDPAVYK[136.11]PLSQEELQR[166.11].L sp|O95628|CNOT4_HUMAN 1 2412.2535 1.95 118440 15135 3 2412.260893 805.0918 CCR4-NOT transcription complex subunit 4 OS=Homo sapiens OX=9606 GN=CNOT4 PE=1 SV=3 4.87 2677 - 97877 - - - 3.0457 - 2.868 0.518 - 104.4 1 2 0 0.0073 20 0 0 0 4.98E+06 2.55E+06 - - - 6.8692 0.9969 221125_WJC_METTL3_EV_vs_WT_F08.15142.15142.3 4.98E-05 Nov-68 K.LLNTVEETTK[136.11]DVSGLHSK[136.11].L "sp|P52732|KIF11_HUMAN,tr|A0A7I2YQY4|A0A7I2YQY4_HUMAN,tr|A0A7I2V3A9|A0A7I2V3A9_HUMAN" 3 1986.0604 7.81 118445 15142 3 1986.070336 663.0274 Kinesin-like protein KIF11 OS=Homo sapiens OX=9606 GN=KIF11 PE=1 SV=2 5.45 2677.9 - 160190 - - - 4.9847 - 2.491 0.477 - 101.9 1 2 1 0.0099 18 0 0 0 1.36E+07 1.74E+06 - - - 6.128 1 221125_WJC_METTL3_EV_vs_WT_F08.15143.15143.2 2.77E-09 Dec-40 R.FSTQC[160.03]QYQGSYSSC[160.03]GPQFQSR.A sp|Q5T749|KPRP_HUMAN 1 2502.0329 999 118446 15143 2 2502.040333 1252.0237 Keratinocyte proline-rich protein OS=Homo sapiens OX=9606 GN=KPRP PE=1 SV=1 8.05 2678.1 - 54518.3 - - - 2.9876 - 2.908 0.725 - 346.3 1 2 0 0.0075 21 0 0 0 5.30E+05 0.00E+00 - - - 7.0179 1 221125_WJC_METTL3_EV_vs_WT_F08.15146.15146.3 9.29E-10 17/80 R.VVNTDHGSPEQLQIPVTDSGR[166.11].H sp|Q6IQ49|SDE2_HUMAN 1 2258.1167 1.89 118447 15146 3 2258.122641 753.7128 Replication stress response regulator SDE2 OS=Homo sapiens OX=9606 GN=SDE2 PE=1 SV=1 4.54 2678.5 - 383114 - - - 2.6496 - 3.57 0.615 - 210.4 1 2 0 0.006 21 0 0 0 4.23E+07 2.24E+07 - - - 8.4459 0.9983 221125_WJC_METTL3_EV_vs_WT_F08.15147.15147.2 0.0754 16-Nov K.VGLQVVAVK[136.11].A "sp|P10809|CH60_HUMAN,tr|A0A7I2V2X6|A0A7I2V2X6_HUMAN,tr|A0A7I2YQK6|A0A7I2YQK6_HUMAN,tr|A0A7I2V599|A0A7I2V599_HUMAN,tr|A0A7I2V5M1|A0A7I2V5M1_HUMAN" 5 919.5946 1.31 118448 15147 2 919.597313 460.8046 "60 kDa heat shock protein, mitochondrial OS=Homo sapiens OX=9606 GN=HSPD1 PE=1 SV=2" 8.72 2678.7 - 369664 - - - 2.947 - 2.351 0.245 - 289 1 2 0 0.0027 9 0 0 0 6.12E+06 4.68E+06 - - - 3.3228 0.9993 221125_WJC_METTL3_EV_vs_WT_F08.15149.15149.4 0.00123 10/120 R.VFQSLPHENK[136.11]PLTLSNYQTNK[136.11].A "sp|P04080|CYTB_HUMAN,tr|A0A1W2PQG6|A0A1W2PQG6_HUMAN" 2 2473.2936 0.57 118450 15149 4 2473.301774 619.3307 Cystatin-B OS=Homo sapiens OX=9606 GN=CSTB PE=1 SV=2 8.48 2678.9 - 436442 - - - 3.2956 - 2.404 0.383 - 43.4 1 2 0 0.0082 21 0 0 0 1.44E+08 2.53E+08 - - - 2.8474 0.9996 221125_WJC_METTL3_EV_vs_WT_F08.15159.15159.4 0.000153 13/120 R.VFQSLPHENKPLTLSNYQTNK.A "sp|P04080|CYTB_HUMAN,tr|A0A1W2PQG6|A0A1W2PQG6_HUMAN" 2 2457.2652 0.56 118458 15159 4 2457.273939 615.3236 Cystatin-B OS=Homo sapiens OX=9606 GN=CSTB PE=1 SV=2 8.48 2680.2 - 331161 - - - 3.547 - 2.275 0.431 - 54.1 1 2 0 0.0087 21 0 0 0 1.43E+08 2.53E+08 - - - 3.2468 0.9335 221125_WJC_METTL3_EV_vs_WT_F08.15163.15163.3 0.135 Jun-36 R.IKFEMEQNLR.Q "sp|P35527|K1C9_HUMAN,tr|K7EQQ3|K7EQQ3_HUMAN" 2 1306.6704 68.73 118462 15163 3 1306.674843 436.5641 "Keratin, type I cytoskeletal 9 OS=Homo sapiens OX=9606 GN=KRT9 PE=1 SV=3" 6.14 2680.7 - 185354 - - - 3.4332 - 1.287 0.296 - 63.7 1 2 1 0.0045 10 0 0 0 1.07E+07 1.55E+05 - - - 2.5757 0.997 221125_WJC_METTL3_EV_vs_WT_F08.15165.15165.2 0.00175 Mar-36 K.GSQC[160.03]QSASSGNEC[160.03]NLGVWK.S sp|Q9UPQ9|TNR6B_HUMAN 1 2067.8738 999 118464 15165 2 2067.876677 1034.9442 Trinucleotide repeat-containing gene 6B protein OS=Homo sapiens OX=9606 GN=TNRC6B PE=1 SV=4 5.99 2681 - 61980.5 - - - 1.3729 - 0.865 0.426 - 11.8 1 2 0 0.0028 19 0 0 0 3.35E+05 0.00E+00 - - - 1.83 0.9531 221125_WJC_METTL3_EV_vs_WT_F08.15170.15170.4 0.00335 8/138 K.EPPFFQPPTAPLPQNPC[160.03]FAC[160.03]PSPC[160.03].P tr|A0A1W2PNU3|A0A1W2PNU3_HUMAN 1 2755.2233 - 118467 15170 4 2755.224937 689.8131 Uncharacterized protein OS=Homo sapiens OX=9606 PE=1 SV=1 4 2681.6 - 286104 - - - 0.5938 - 1.606 0.353 - 19.6 1 1 0 0.0016 24 0 0 0 - - - - - 2.4501 0.9925 221125_WJC_METTL3_EV_vs_WT_F08.15171.15171.4 0.000136 10/120 R.TPSKIPYSDVNIGTGVAHPPR.W "sp|Q9UKM7|MA1B1_HUMAN,tr|A0A804HK28|A0A804HK28_HUMAN,tr|H0YG20|H0YG20_HUMAN,tr|A0A804HKS1|A0A804HKS1_HUMAN,tr|H0YGV7|H0YGV7_HUMAN,tr|A0A804HL65|A0A804HL65_HUMAN,tr|A0A804HIP1|A0A804HIP1_HUMAN,tr|A0A804HK01|A0A804HK01_HUMAN,tr|A0A804HJ23|A0A804HJ23_HUMAN,tr|A0A804HHU1|A0A804HHU1_HUMAN,tr|A0A804HK86|A0A804HK86_HUMAN,tr|A0A804HL61|A0A804HL61_HUMAN,tr|A0A804HJ66|A0A804HJ66_HUMAN,tr|H0YGQ1|H0YGQ1_HUMAN,tr|H0YI64|H0YI64_HUMAN,tr|A0A804HJW0|A0A804HJW0_HUMAN" 16 2205.1542 1.57 118468 15171 4 2205.164419 552.2958 "Endoplasmic reticulum mannosyl-oligosaccharide 1,2-alpha-mannosidase OS=Homo sapiens OX=9606 GN=MAN1B1 PE=1 SV=2" 8.29 2681.8 - 193552 - - - 4.6269 - 2.411 0.383 - 45.3 1 2 1 0.0102 21 0 0 0 4.33E+06 2.76E+06 - - - 2.8478 0.9998 221125_WJC_METTL3_EV_vs_WT_F08.15174.15174.4 7.09E-08 14/84 R.QAAVGQGDFHLLDHR.G "sp|O43819|SCO2_HUMAN,tr|A0A1W2PQK0|A0A1W2PQK0_HUMAN" 2 1662.8227 1.01 118471 15174 4 1662.831091 416.7129 "Protein SCO2 homolog, mitochondrial OS=Homo sapiens OX=9606 GN=SCO2 PE=1 SV=3" 5.98 2682.2 - 140837 - - - 5.0751 - 2.9 0.576 - 126.7 1 2 0 0.0084 15 0 0 0 9.92E+06 9.82E+06 - - - 4.6181 0.9992 221125_WJC_METTL3_EV_vs_WT_F08.15183.15183.3 0.000144 13/60 K.NQVALNPQNTVFDAK[136.11]R[166.11].L "sp|P0DMV8|HS71A_HUMAN,sp|P0DMV9|HS71B_HUMAN,tr|A0A0G2JIW1|A0A0G2JIW1_HUMAN" 3 1831.966 0.1 118478 15183 3 1831.973579 611.6626 Heat shock 70 kDa protein 1A OS=Homo sapiens OX=9606 GN=HSPA1A PE=1 SV=1 8.75 2683.4 - 278392 - - - 4.1562 - 2.578 0.391 - 188.1 1 2 0 0.0076 16 0 0 0 2.27E+06 2.19E+07 - - - 5.3271 1 221125_WJC_METTL3_EV_vs_WT_F08.15184.15184.3 1.14E-08 Dec-76 K.WR[166.11]PGDADGTDC[160.03]TSIGTIEQK[136.11].S sp|Q9BTC0|DIDO1_HUMAN 1 2224.0185 0.4 118479 15184 3 2224.022166 742.3468 Death-inducer obliterator 1 OS=Homo sapiens OX=9606 GN=DIDO1 PE=1 SV=5 4.23 2683.5 - 178064 - - - 1.6344 - 2.473 0.639 - 148.5 1 2 0 0.0036 20 0 0 0 2.99E+06 7.55E+06 - - - 7.8598 1 221125_WJC_METTL3_EV_vs_WT_F08.15196.15196.3 5.43E-07 13/56 R.QAAVGQGDFHLLDHR.G "sp|O43819|SCO2_HUMAN,tr|A0A1W2PQK0|A0A1W2PQK0_HUMAN" 2 1662.8227 0.7 118489 15196 3 1662.822701 555.2815 "Protein SCO2 homolog, mitochondrial OS=Homo sapiens OX=9606 GN=SCO2 PE=1 SV=3" 5.98 2685.1 - 202274 - - - 0.0295 - 2.875 0.5 - 177.9 1 2 0 0 15 0 0 0 4.81E+06 6.88E+06 - - - 6.8701 0.9998 221125_WJC_METTL3_EV_vs_WT_F08.15207.15207.3 8.86E-05 Sep-92 K.AQAVTQPVPLANK[136.11]PVPAQSTFPSK[136.11].T "sp|P49750|YLPM1_HUMAN,tr|H0YIQ2|H0YIQ2_HUMAN" 2 2491.377 1.68 118496 15207 3 2491.381497 831.4663 YLP motif-containing protein 1 OS=Homo sapiens OX=9606 GN=YLPM1 PE=1 SV=4 10 2686.6 - 223503 - - - 1.8215 - 2.242 0.44 - 46.4 1 2 0 0.0045 24 0 0 0 6.90E+07 4.09E+07 - - - 5.3195 0.9939 221125_WJC_METTL3_EV_vs_WT_F08.15215.15215.3 2.26E-05 13/68 K.YVHYEIDAC[160.03]MDSEAPGSK[136.11].D "sp|Q86U44|MTA70_HUMAN,tr|H0YFV6|H0YFV6_HUMAN" 2 2078.8805 0.01 118502 15215 3 2079.875848 693.9674 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 4.31 2687.7 - 1.14E+06 - - - 478.7942 - 2.611 0.524 - 183.7 1 2 0 0.9954 18 0 0 0 2.88E+05 3.49E+07 - - - 6.4962 0.9951 221125_WJC_METTL3_EV_vs_WT_F08.15222.15222.4 0.00503 10/102 K.NLVTGDHIPTPQDLPQR[166.11]K[136.11].S "sp|O43768|ENSA_HUMAN,tr|Q5T5H1|Q5T5H1_HUMAN,tr|A0A1W2PRU0|A0A1W2PRU0_HUMAN,tr|A6NMQ3|A6NMQ3_HUMAN" 4 2046.0977 0.66 118509 15222 4 2046.105003 512.5317 Alpha-endosulfine OS=Homo sapiens OX=9606 GN=ENSA PE=1 SV=1 6.75 2688.6 - 114191 - - - 3.5653 - 2.024 0.295 - 66.3 1 2 0 0.0073 18 0 0 0 1.49E+07 2.25E+07 - - - 2.0332 1 221125_WJC_METTL3_EV_vs_WT_F08.15226.15226.4 2.09E-10 20/114 K.VAHPIRPKPPSATSIPAILK.A "sp|Q9UMS4|PRP19_HUMAN,tr|F5GY56|F5GY56_HUMAN" 2 2092.2521 1.3 118512 15226 4 2092.260776 524.0703 Pre-mRNA-processing factor 19 OS=Homo sapiens OX=9606 GN=PRPF19 PE=1 SV=1 11.17 2689.1 - 5.23E+06 - - - 4.1563 - 3.56 0.657 - 193.2 1 2 0 0.0087 20 0 0 0 1.55E+08 1.19E+08 - - - 5.3666 0.9998 221125_WJC_METTL3_EV_vs_WT_F08.15232.15232.2 8.35E-06 22-Oct K.NVQDAIADAEQR.G sp|P35908|K22E_HUMAN 1 1328.6321 26.11 118517 15232 2 1328.63332 665.3233 "Keratin, type II cytoskeletal 2 epidermal OS=Homo sapiens OX=9606 GN=KRT2 PE=1 SV=2" 4.03 2689.9 - 263331 - - - 0.9506 - 2.14 0.484 - 346.8 1 2 0 0.0013 12 0 0 0 3.19E+07 1.22E+06 - - - 4.6172 0.9815 221125_WJC_METTL3_EV_vs_WT_F08.15233.15233.2 3.48E-06 Sep-32 N.IVSNASC[160.03]TTNC[160.03]LAPLAK.V "sp|O14556|G3PT_HUMAN,tr|K7EP73|K7EP73_HUMAN" 2 1818.8968 999 118518 15233 2 1818.899725 910.4557 "Glyceraldehyde-3-phosphate dehydrogenase, testis-specific OS=Homo sapiens OX=9606 GN=GAPDHS PE=1 SV=2" 8.06 2690 - 83404.9 - - - 1.6054 - 1.842 0.508 - 155.8 1 1 0 0.0029 17 0 0 0 1.61E+06 0.00E+00 - - - 4.294 0.998 221125_WJC_METTL3_EV_vs_WT_F08.15239.15239.3 5.23E-06 14/52 R.NLDIER[166.11]PTYTNLNR[166.11].L "sp|Q9NY65|TBA8_HUMAN,sp|Q6PEY2|TBA3E_HUMAN,sp|P0DPH7|TBA3C_HUMAN,sp|Q71U36|TBA1A_HUMAN,sp|P0DPH8|TBA3D_HUMAN,sp|Q9H853|TBA4B_HUMAN,sp|P68366|TBA4A_HUMAN,sp|P68363|TBA1B_HUMAN,sp|Q9BQE3|TBA1C_HUMAN,tr|F8VVB9|F8VVB9_HUMAN,tr|C9JDS9|C9JDS9_HUMAN,tr|A0A7P0TA31|A0A7P0TA31_HUMAN,tr|F5H5D3|F5H5D3_HUMAN,tr|C9J2C0|C9J2C0_HUMAN,tr|F8VQQ4|F8VQQ4_HUMAN,tr|A0A7P0T945|A0A7P0T945_HUMAN" 16 1737.8913 0.73 118522 15239 3 1737.900719 580.3044 Tubulin alpha-8 chain OS=Homo sapiens OX=9606 GN=TUBA8 PE=1 SV=1 6.07 2690.8 - 324866 - - - 5.4273 - 2.513 0.385 - 256.2 1 2 0 0.0094 14 0 0 0 6.10E+06 8.31E+06 - - - 5.2786 0.9656 221125_WJC_METTL3_EV_vs_WT_F08.15242.15242.4 0.00201 8/102 K.VGGAEGTK[136.11]LDDDFK[136.11]EMEK[136.11].K sp|Q99961|SH3G1_HUMAN 1 1991.9572 2.05 118525 15242 4 1992.962388 498.9966 Endophilin-A2 OS=Homo sapiens OX=9606 GN=SH3GL1 PE=1 SV=1 4.3 2691.2 - 168872 - - - 504.6117 - 2.012 0.388 - 58.4 1 2 2 1.0052 18 0 0 0 8.56E+07 4.17E+07 - - - 2.5642 0.9989 221125_WJC_METTL3_EV_vs_WT_F08.15246.15246.4 0.000151 14/102 K.VGGAEGTKLDDDFKEMEK.K sp|Q99961|SH3G1_HUMAN 1 1967.9146 2.09 118527 15246 4 1967.920151 492.9859 Endophilin-A2 OS=Homo sapiens OX=9606 GN=SH3GL1 PE=1 SV=1 4.3 2691.7 - 221398 - - - 2.8091 - 2.908 0.416 - 144.2 1 2 2 0.0055 18 0 0 0 8.71E+07 4.17E+07 - - - 3.211 1 221125_WJC_METTL3_EV_vs_WT_F08.15247.15247.3 2.01E-09 14/80 R.NPNASHSDSVLVQIDATEGNK[136.11].V "sp|Q709C8|VP13C_HUMAN,tr|A0A3B3IU50|A0A3B3IU50_HUMAN" 2 2203.0597 0.01 118528 15247 3 2203.063491 735.3605 Vacuolar protein sorting-associated protein 13C OS=Homo sapiens OX=9606 GN=VPS13C PE=1 SV=1 4.54 2691.9 - 266438 - - - 1.7417 - 3.375 0.595 - 235 1 2 0 0.0038 21 0 0 0 2.82E+04 4.21E+06 - - - 8.0889 1 221125_WJC_METTL3_EV_vs_WT_F08.15253.15253.4 2.87E-07 16/108 K.IFGDLSHQLDQPGHSDEQR.E "sp|Q9NQY0|BIN3_HUMAN,tr|H7BYV6|H7BYV6_HUMAN" 2 2178.009 1.75 118532 15253 4 2178.014787 545.5095 Bridging integrator 3 OS=Homo sapiens OX=9606 GN=BIN3 PE=1 SV=1 4.64 2692.6 - 466979 - - - 2.6529 - 2.919 0.572 - 127.9 1 2 0 0.0058 19 0 0 0 1.17E+07 6.70E+06 - - - 4.5655 0.9881 221125_WJC_METTL3_EV_vs_WT_F08.15255.15255.4 12.2 12/132 F.MLQNEPLPHSC[160.03]NWVAASGPC[160.03]DK[136.11]R[166.11].F sp|Q9H7S9|ZN703_HUMAN 1 2684.2377 2.03 118534 15255 4 2684.237208 672.0667 Zinc finger protein 703 OS=Homo sapiens OX=9606 GN=ZNF703 PE=1 SV=1 6.5 2692.9 - 256363 - - - -0.1706 - 2.553 0.421 - 77.5 1 1 0 -0.0005 23 0 0 0 1.01E+07 4.98E+06 - - - 3.1939 1 221125_WJC_METTL3_EV_vs_WT_F08.15261.15261.3 8.23E-14 17/64 K.HSSGQQNLNTITYETLK[136.11].Y "sp|O75575|RPC9_HUMAN,tr|H7C0S8|H7C0S8_HUMAN" 2 1940.9683 1.96 118538 15261 3 1940.961961 647.9967 DNA-directed RNA polymerase III subunit RPC9 OS=Homo sapiens OX=9606 GN=CRCP PE=1 SV=1 6.75 2693.7 - 157972 - - - -3.2762 - 3.492 0.69 - 459.4 1 2 0 -0.0064 17 0 0 0 2.14E+07 1.09E+07 - - - 9.3901 1 221125_WJC_METTL3_EV_vs_WT_F08.15265.15265.3 6.28E-16 28/80 R.VFQSLPHENKPLTLSNYQTNK.A "sp|P04080|CYTB_HUMAN,tr|A0A1W2PQG6|A0A1W2PQG6_HUMAN" 2 2457.2652 0.82 118541 15265 3 2457.268934 820.0957 Cystatin-B OS=Homo sapiens OX=9606 GN=CSTB PE=1 SV=2 8.48 2694.2 - 1.17E+06 - - - 1.5102 - 4.305 0.672 - 934.7 1 2 0 0.0037 21 0 0 0 2.25E+07 2.76E+07 - - - 9.5309 0.9999 221125_WJC_METTL3_EV_vs_WT_F08.15268.15268.3 1.85E-07 Aug-92 R.VLR[166.11]PQVTAVAQQNQGEVPEPQDMK[136.11].V "sp|Q14204|DYHC1_HUMAN,tr|A0A7P0T8N2|A0A7P0T8N2_HUMAN,tr|A0A7P0T9C4|A0A7P0T9C4_HUMAN,tr|A0A7P0TBJ7|A0A7P0TBJ7_HUMAN,tr|A0A804HHY6|A0A804HHY6_HUMAN,tr|A0A7P0T9K2|A0A7P0T9K2_HUMAN,tr|A0A7P0TB64|A0A7P0TB64_HUMAN,tr|A0A2R8Y706|A0A2R8Y706_HUMAN,tr|A0A7P0T916|A0A7P0T916_HUMAN,tr|A0A7P0TB75|A0A7P0TB75_HUMAN,tr|A0A7P0T8W5|A0A7P0T8W5_HUMAN,tr|A0A7P0T9S3|A0A7P0T9S3_HUMAN,tr|A0A7P0TAF3|A0A7P0TAF3_HUMAN,tr|A0A7P0T9F1|A0A7P0T9F1_HUMAN,tr|A0A7P0TAW9|A0A7P0TAW9_HUMAN,tr|A0A2R8YGC7|A0A2R8YGC7_HUMAN,tr|A0A7P0TA13|A0A7P0TA13_HUMAN,tr|A0A7P0T934|A0A7P0T934_HUMAN,tr|A0A7P0TAV5|A0A7P0TAV5_HUMAN,tr|A0A7P0T9Y3|A0A7P0T9Y3_HUMAN,tr|A0A7P0T7V5|A0A7P0T7V5_HUMAN,tr|A0A7P0T9R4|A0A7P0T9R4_HUMAN,tr|A0A2R8Y5T0|A0A2R8Y5T0_HUMAN,tr|A0A7P0T990|A0A7P0T990_HUMAN,tr|A0A7P0T942|A0A7P0T942_HUMAN,tr|A0A2R8YFZ7|A0A2R8YFZ7_HUMAN,tr|A0A7P0T825|A0A7P0T825_HUMAN,tr|A0A2R8Y6H2|A0A2R8Y6H2_HUMAN,tr|A0A7P0TBC9|A0A7P0TBC9_HUMAN,tr|A0A7P0TAM4|A0A7P0TAM4_HUMAN" 30 2679.3769 0.4 118544 15268 3 2679.383864 894.1329 Cytoplasmic dynein 1 heavy chain 1 OS=Homo sapiens OX=9606 GN=DYNC1H1 PE=1 SV=5 4.68 2694.6 - 147030 - - - 2.592 - 1.719 0.576 - 40.4 1 2 0 0.0069 24 0 0 0 2.70E+06 6.77E+06 - - - 6.2182 1 221125_WJC_METTL3_EV_vs_WT_F08.15271.15271.3 8.47E-13 24/68 K.VGGAEGTKLDDDFKEMEK.K sp|Q99961|SH3G1_HUMAN 1 1967.9146 1.56 118545 15271 3 1967.917023 656.9788 Endophilin-A2 OS=Homo sapiens OX=9606 GN=SH3GL1 PE=1 SV=1 4.3 2695 - 636052 - - - 1.2196 - 4.648 0.653 - 1124.9 1 2 2 0.0024 18 0 0 0 4.15E+07 2.65E+07 - - - 9.6455 0.9964 221125_WJC_METTL3_EV_vs_WT_F08.15272.15272.3 0.0147 Sep-52 K.K[136.11]GPGEVAGTVTGQK[136.11].R "sp|Q86U44|MTA70_HUMAN,tr|F5H6D8|F5H6D8_HUMAN,tr|H0YFV6|H0YFV6_HUMAN,tr|B4DTN4|B4DTN4_HUMAN" 4 1343.738 0.001 118546 15272 3 1343.742092 448.9199 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 8.59 2695.1 - 841061 - - - 3.0609 - 1.904 0.307 - 80.4 4 2 0 0.0041 14 0 0 0 0.00E+00 4.50E+06 - - - 3.3943 1 221125_WJC_METTL3_EV_vs_WT_F08.15273.15273.3 4.43E-07 24/68 K.VGGAEGTK[136.11]LDDDFK[136.11]EMEK[136.11].K sp|Q99961|SH3G1_HUMAN 1 1991.9572 1.56 118547 15273 3 1991.95947 664.993 Endophilin-A2 OS=Homo sapiens OX=9606 GN=SH3GL1 PE=1 SV=1 4.3 2695.3 - 568880 - - - 1.128 - 4.687 0.602 - 799.7 1 2 2 0.0022 18 0 0 0 4.15E+07 2.65E+07 - - - 9.0978 0.995 221125_WJC_METTL3_EV_vs_WT_F08.15274.15274.4 3.09E-05 18/132 F.MLQNEPLPHSC[160.03]NWVAASGPC[160.03]DKR.F sp|Q9H7S9|ZN703_HUMAN 1 2666.2152 2.03 118548 15274 4 2666.220133 667.5611 Zinc finger protein 703 OS=Homo sapiens OX=9606 GN=ZNF703 PE=1 SV=1 6.5 2695.4 - 457272 - - - 1.8517 - 3.4 0.51 - 171.8 1 1 0 0.0049 23 0 0 0 1.01E+07 4.98E+06 - - - 4.0602 1 221125_WJC_METTL3_EV_vs_WT_F08.15275.15275.4 8.59E-10 23/114 R.LHLGSTPHNLTDANIHELAR[166.11].K "sp|Q9UN37|VPS4A_HUMAN,tr|I3L4J1|I3L4J1_HUMAN" 2 2218.1482 0.79 118549 15275 4 2218.149725 555.5443 Vacuolar protein sorting-associated protein 4A OS=Homo sapiens OX=9606 GN=VPS4A PE=1 SV=1 6.26 2695.5 - 384864 - - - 0.6726 - 3.827 0.559 - 340.2 1 2 0 0.0015 20 0 0 0 1.34E+07 1.69E+07 - - - 4.5398 0.9987 221125_WJC_METTL3_EV_vs_WT_F08.15277.15277.3 1.79E-06 Dec-40 K.TTLLHMLK[136.11]DDR[166.11].L "sp|Q9NR31|SAR1A_HUMAN,sp|Q9Y6B6|SAR1B_HUMAN,tr|D6RAA2|D6RAA2_HUMAN,tr|D6RD69|D6RD69_HUMAN,tr|X1WI22|X1WI22_HUMAN,tr|Q5SQT8|Q5SQT8_HUMAN,tr|D6RDB2|D6RDB2_HUMAN" 7 1359.7299 0.79 118551 15277 3 1359.734496 454.2506 GTP-binding protein SAR1a OS=Homo sapiens OX=9606 GN=SAR1A PE=1 SV=1 6.41 2695.8 - 218074 - - - 3.3499 - 2.294 0.436 - 259.3 1 2 1 0.0046 11 0 0 0 4.24E+06 5.40E+06 - - - 5.7584 1 221125_WJC_METTL3_EV_vs_WT_F08.15280.15280.3 2.61E-08 16/56 R.STSHK[136.11]PDEIYGMIER[166.11].L sp|Q86U44|MTA70_HUMAN 1 1779.8581 0.02 118553 15280 3 1779.860323 594.2933 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 5.42 2696.1 - 1.82E+06 - - - 1.2748 - 3.041 0.578 - 346.3 1 2 0 0.0023 15 0 0 0 2.03E+06 1.06E+08 - - - 7.8856 0.9729 221125_WJC_METTL3_EV_vs_WT_F08.15283.15283.3 0.000189 8/104 R.AGAGQRPLTPNQGQQGQQAESLAAAAA.A "sp|Q8TB72|PUM2_HUMAN,tr|A0A0C4DG68|A0A0C4DG68_HUMAN" 2 2590.2848 2.41 118555 15283 3 2590.288875 864.4355 Pumilio homolog 2 OS=Homo sapiens OX=9606 GN=PUM2 PE=1 SV=2 6.05 2696.5 - 276876 - - - 1.577 - 1.549 0.46 - 40.7 1 1 0 0.0041 27 0 0 0 2.12E+07 8.77E+06 - - - 4.6742 0.9999 221125_WJC_METTL3_EV_vs_WT_F08.15284.15284.4 0.000883 16/102 R.VIAPSSSLPTSLTIHHPR.E sp|Q02413|DSG1_HUMAN 1 1912.053 2.13 118556 15284 4 1912.057477 479.0205 Desmoglein-1 OS=Homo sapiens OX=9606 GN=DSG1 PE=1 SV=2 9.73 2696.6 - 192001 - - - 2.3174 - 3.219 0.456 - 261.6 1 2 0 0.0044 18 0 0 0 9.64E+06 4.52E+06 - - - 3.5943 0.9999 221125_WJC_METTL3_EV_vs_WT_F08.15288.15288.4 4.25E-06 14/120 R.K[136.11]EVVVYLDDNQK[136.11]PPVGEGLNR[166.11].K "sp|P52948|NUP98_HUMAN,tr|A0A3B3ITD8|A0A3B3ITD8_HUMAN" 2 2394.2753 2.49 118558 15288 4 2394.276694 599.5761 Nuclear pore complex protein Nup98-Nup96 OS=Homo sapiens OX=9606 GN=NUP98 PE=1 SV=4 4.78 2697 - 411429 - - - 0.5638 - 2.631 0.434 - 111.1 1 2 0 0.0014 21 0 0 0 3.30E+07 1.32E+07 - - - 3.323 0.9974 221125_WJC_METTL3_EV_vs_WT_F08.15292.15292.3 6.31E-06 Nov-84 R.QLAHQAQQQLEEEEEDTPVSPK[136.11].E sp|Q14147|DHX34_HUMAN 1 2541.2074 2.31 118562 15292 3 2542.20269 848.0764 Probable ATP-dependent RNA helicase DHX34 OS=Homo sapiens OX=9606 GN=DHX34 PE=1 SV=2 4.14 2697.6 - 220475 - - - 391.6445 - 2.292 0.608 - 119.5 1 2 0 0.9952 22 0 0 0 2.54E+06 1.10E+06 - - - 7.0093 0.9998 221125_WJC_METTL3_EV_vs_WT_F08.15294.15294.4 0.000118 Nov-96 K.WAEK[136.11]PAFGTPLEEHLK[136.11]R[166.11].S sp|Q68EM7|RHG17_HUMAN 1 2034.0897 1.58 118564 15294 4 2034.095462 509.5297 Rho GTPase-activating protein 17 OS=Homo sapiens OX=9606 GN=ARHGAP17 PE=1 SV=1 6.76 2697.8 - 210087 - - - 2.8249 - 2.075 0.44 - 78 1 2 0 0.0057 17 0 0 0 3.49E+07 2.21E+07 - - - 3.3076 0.9999 221125_WJC_METTL3_EV_vs_WT_F08.15298.15298.4 0.000185 Nov-90 K.KAADHLKPFLDDSTLR.F sp|O43395|PRPF3_HUMAN 1 1825.9686 3.18 118566 15298 4 1825.967532 457.4994 U4\U6 small nuclear ribonucleoprotein Prp3 OS=Homo sapiens OX=9606 GN=PRPF3 PE=1 SV=2 6.75 2698.3 - 536324 - - - -0.6106 - 2.642 0.418 - 135.9 1 2 0 -0.0011 16 0 0 0 3.22E+07 1.01E+07 - - - 3.2062 0.8513 221125_WJC_METTL3_EV_vs_WT_F08.15299.15299.3 0.00584 12/104 R.AGAGQR[166.11]PLTPNQGQQGQQAESLAAAAA.A "sp|Q8TB72|PUM2_HUMAN,tr|A0A0C4DG68|A0A0C4DG68_HUMAN" 2 2600.2931 2.41 118567 15299 3 2600.284865 867.7716 Pumilio homolog 2 OS=Homo sapiens OX=9606 GN=PUM2 PE=1 SV=2 6.05 2698.5 - 209845 - - - -3.1516 - 2.032 0.344 - 17.1 1 1 0 -0.0082 27 0 0 0 2.12E+07 8.77E+06 - - - 4.0042 1 221125_WJC_METTL3_EV_vs_WT_F08.15300.15300.3 2.85E-10 20/92 K.AQAVTQPVPLANKPVPAQSTFPSK.T "sp|P49750|YLPM1_HUMAN,tr|H0YIQ2|H0YIQ2_HUMAN" 2 2475.3486 1.68 118568 15300 3 2475.351293 826.1235 YLP motif-containing protein 1 OS=Homo sapiens OX=9606 GN=YLPM1 PE=1 SV=4 10 2698.6 - 1.44E+06 - - - 1.1045 - 3.759 0.599 - 265.1 1 2 0 0.0027 24 0 0 0 6.88E+07 4.09E+07 - - - 8.293 1 221125_WJC_METTL3_EV_vs_WT_F08.15301.15301.3 6.82E-10 22/64 K.HSSGQQNLNTITYETLK.Y "sp|O75575|RPC9_HUMAN,tr|H7C0S8|H7C0S8_HUMAN" 2 1932.9541 1.97 118569 15301 3 1932.954762 645.3253 DNA-directed RNA polymerase III subunit RPC9 OS=Homo sapiens OX=9606 GN=CRCP PE=1 SV=1 6.75 2698.7 - 697890 - - - 0.3321 - 4.385 0.676 - 966.8 1 2 0 0.0006 17 0 0 0 2.17E+07 1.10E+07 - - - 9.8109 0.9998 221125_WJC_METTL3_EV_vs_WT_F08.15302.15302.4 0.00264 18/96 K.WAEKPAFGTPLEEHLKR.S sp|Q68EM7|RHG17_HUMAN 1 2008.053 1.59 118570 15302 4 2008.054009 503.0205 Rho GTPase-activating protein 17 OS=Homo sapiens OX=9606 GN=ARHGAP17 PE=1 SV=1 6.76 2698.9 - 330863 - - - 0.4796 - 2.989 0.385 - 216.9 1 2 0 0.001 17 0 0 0 3.50E+07 2.20E+07 - - - 2.9569 1 221125_WJC_METTL3_EV_vs_WT_F08.15303.15303.2 4.43E-08 15/42 K.DHTPSQELALTQSVGGDSSADR[166.11].L "sp|Q86U44|MTA70_HUMAN,tr|H0YFV6|H0YFV6_HUMAN" 2 2280.0494 0.01 118571 15303 2 2280.04434 1141.032 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 4.22 2699 - 310518 - - - -2.2048 - 2.987 0.647 - 191.2 1 2 0 -0.005 22 0 0 0 3.11E+06 3.10E+08 - - - 6.5085 1 221125_WJC_METTL3_EV_vs_WT_F08.15304.15304.3 1.76E-11 25/100 R.SPR[166.11]PTSAPAITQGQVAEGGVLDASAK[136.11].K "sp|P11171|EPB41_HUMAN,tr|A0A2R8Y6D0|A0A2R8Y6D0_HUMAN,tr|A0A2R8YFR9|A0A2R8YFR9_HUMAN,tr|A0A2R8Y420|A0A2R8Y420_HUMAN,tr|A0A2R8YCW8|A0A2R8YCW8_HUMAN,tr|A0A2R8Y7N0|A0A2R8Y7N0_HUMAN,tr|A0A3B3ITP0|A0A3B3ITP0_HUMAN,tr|A0A2R8Y5C8|A0A2R8Y5C8_HUMAN,tr|A0A3B3IU06|A0A3B3IU06_HUMAN,tr|A0A2R8Y5G2|A0A2R8Y5G2_HUMAN,tr|A0A1B0GWG0|A0A1B0GWG0_HUMAN,tr|A0A2U3TZH6|A0A2U3TZH6_HUMAN,tr|A0A3B3IUD6|A0A3B3IUD6_HUMAN,tr|A0A2R8Y7Y3|A0A2R8Y7Y3_HUMAN,tr|A0A2R8Y570|A0A2R8Y570_HUMAN,tr|A0A2R8Y6G5|A0A2R8Y6G5_HUMAN,tr|A0A2R8Y5Z6|A0A2R8Y5Z6_HUMAN,tr|A0A2R8YD30|A0A2R8YD30_HUMAN,tr|A0A2R8Y4N6|A0A2R8Y4N6_HUMAN" 19 2525.3205 1.09 118572 15304 3 2525.321946 842.7808 Protein 4.1 OS=Homo sapiens OX=9606 GN=EPB41 PE=1 SV=4 5.79 2699.1 - 290462 - - - 0.5924 - 4.973 0.675 - 765.7 1 2 0 0.0015 26 0 0 0 5.11E+07 4.68E+07 - - - 9.7554 0.9875 221125_WJC_METTL3_EV_vs_WT_F08.15305.15305.4 0.0712 Aug-90 K.K[136.11]AADHLK[136.11]PFLDDSTLR[166.11].F sp|O43395|PRPF3_HUMAN 1 1852.0053 3.31 118573 15305 4 1852.006304 464.0086 U4\U6 small nuclear ribonucleoprotein Prp3 OS=Homo sapiens OX=9606 GN=PRPF3 PE=1 SV=2 6.75 2699.2 - 244266 - - - 0.5329 - 1.923 0.214 - 70.5 2 2 0 0.001 16 0 0 0 3.19E+07 9.63E+06 - - - 1.0893 1 221125_WJC_METTL3_EV_vs_WT_F08.15306.15306.4 0.00528 Sep-72 R.EDAMAMVDHC[160.03]LKK.A "sp|P43243|MATR3_HUMAN,tr|B3KM87|B3KM87_HUMAN,tr|A8MXP9|A8MXP9_HUMAN,tr|A0A0R4J2E8|A0A0R4J2E8_HUMAN,tr|H0Y8T4|H0Y8T4_HUMAN,tr|D6REM6|D6REM6_HUMAN" 6 1546.6942 1.25 118574 15306 4 1546.692236 387.6808 Matrin-3 OS=Homo sapiens OX=9606 GN=MATR3 PE=1 SV=2 5.38 2699.4 - 240456 - - - -1.273 - 2.171 0.498 - 63.3 1 2 0 -0.002 13 0 0 0 8.64E+06 6.92E+06 - - - 3.8475 1 221125_WJC_METTL3_EV_vs_WT_F08.15307.15307.3 1.93E-06 24/100 R.SPRPTSAPAITQGQVAEGGVLDASAK.K "sp|P11171|EPB41_HUMAN,tr|A0A2R8Y6D0|A0A2R8Y6D0_HUMAN,tr|A0A2R8YFR9|A0A2R8YFR9_HUMAN,tr|A0A2R8Y420|A0A2R8Y420_HUMAN,tr|A0A2R8YCW8|A0A2R8YCW8_HUMAN,tr|A0A2R8Y7N0|A0A2R8Y7N0_HUMAN,tr|A0A3B3ITP0|A0A3B3ITP0_HUMAN,tr|A0A2R8Y5C8|A0A2R8Y5C8_HUMAN,tr|A0A3B3IU06|A0A3B3IU06_HUMAN,tr|A0A2R8Y5G2|A0A2R8Y5G2_HUMAN,tr|A0A1B0GWG0|A0A1B0GWG0_HUMAN,tr|A0A2U3TZH6|A0A2U3TZH6_HUMAN,tr|A0A3B3IUD6|A0A3B3IUD6_HUMAN,tr|A0A2R8Y7Y3|A0A2R8Y7Y3_HUMAN,tr|A0A2R8Y570|A0A2R8Y570_HUMAN,tr|A0A2R8Y6G5|A0A2R8Y6G5_HUMAN,tr|A0A2R8Y5Z6|A0A2R8Y5Z6_HUMAN,tr|A0A2R8YD30|A0A2R8YD30_HUMAN,tr|A0A2R8Y4N6|A0A2R8Y4N6_HUMAN" 19 2507.298 1.09 118575 15307 3 2507.292492 836.7733 Protein 4.1 OS=Homo sapiens OX=9606 GN=EPB41 PE=1 SV=4 5.79 2699.5 - 223492 - - - -2.1888 - 4.661 0.634 - 591.1 1 2 0 -0.0055 26 0 0 0 5.11E+07 4.68E+07 - - - 9.1482 1 221125_WJC_METTL3_EV_vs_WT_F08.15310.15310.4 2.59E-08 18/114 K.VAHPIR[166.11]PK[136.11]PPSATSIPAILK[136.11].A "sp|Q9UMS4|PRP19_HUMAN,tr|F5GY56|F5GY56_HUMAN" 2 2118.2888 1.51 118577 15310 4 2118.289757 530.5795 Pre-mRNA-processing factor 19 OS=Homo sapiens OX=9606 GN=PRPF19 PE=1 SV=1 11.17 2699.9 - 5.12E+06 - - - 0.4754 - 3.215 0.591 - 179 1 2 0 0.001 20 0 0 0 1.19E+08 7.89E+07 - - - 4.7602 1 221125_WJC_METTL3_EV_vs_WT_F08.15315.15315.3 8.88E-09 13/60 K.KAADHLKPFLDDSTLR.F sp|O43395|PRPF3_HUMAN 1 1825.9686 14.25 118581 15315 3 1825.965013 609.6635 U4\U6 small nuclear ribonucleoprotein Prp3 OS=Homo sapiens OX=9606 GN=PRPF3 PE=1 SV=2 6.75 2700.4 - 396616 - - - -1.9902 - 2.838 0.516 - 209.6 1 2 0 -0.0036 16 0 0 0 1.78E+07 1.25E+06 - - - 6.9683 0.9992 221125_WJC_METTL3_EV_vs_WT_F08.15317.15317.3 0.00961 Aug-48 R.EDAMAMVDHC[160.03]LKK.A "sp|P43243|MATR3_HUMAN,tr|B3KM87|B3KM87_HUMAN,tr|A8MXP9|A8MXP9_HUMAN,tr|A0A0R4J2E8|A0A0R4J2E8_HUMAN,tr|H0Y8T4|H0Y8T4_HUMAN,tr|D6REM6|D6REM6_HUMAN" 6 1546.6942 1.04 118583 15317 3 1546.690189 516.572 Matrin-3 OS=Homo sapiens OX=9606 GN=MATR3 PE=1 SV=2 5.38 2700.6 - 305606 - - - -2.5965 - 1.764 0.373 - 43.9 1 2 0 -0.004 13 0 0 0 7.32E+06 7.04E+06 - - - 4.2364 0.9689 221125_WJC_METTL3_EV_vs_WT_F08.15320.15320.4 0.0799 13/84 K.KKPIYINVIRDPIER.L "sp|Q7LGA3|HS2ST_HUMAN,tr|K7EP71|K7EP71_HUMAN" 2 1853.0887 1.09 118584 15320 4 1853.085957 464.2795 Heparan sulfate 2-O-sulfotransferase 1 OS=Homo sapiens OX=9606 GN=HS2ST1 PE=1 SV=1 9.7 2701 - 299898 - - - -1.4819 - 1.979 0.206 - 167 1 2 1 -0.0027 15 0 0 0 1.61E+07 1.47E+07 - - - 1.2625 0.9995 221125_WJC_METTL3_EV_vs_WT_F08.15324.15324.3 8.53E-05 Dec-76 K.VAHPIR[166.11]PK[136.11]PPSATSIPAILK[136.11].A "sp|Q9UMS4|PRP19_HUMAN,tr|F5GY56|F5GY56_HUMAN" 2 2118.2888 1.28 118587 15324 3 2118.279963 707.1035 Pre-mRNA-processing factor 19 OS=Homo sapiens OX=9606 GN=PRPF19 PE=1 SV=1 11.17 2701.5 - 465704 - - - -4.1482 - 2.083 0.482 - 109.7 1 2 0 -0.0088 20 0 0 0 2.99E+07 2.34E+07 - - - 5.6916 0.9997 221125_WJC_METTL3_EV_vs_WT_F08.15334.15334.4 3.47E-05 17/84 R.STSHK[136.11]PDEIYGMIER[166.11].L sp|Q86U44|MTA70_HUMAN 1 1779.8581 0.001 118592 15334 4 1779.850693 445.9718 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 5.42 2702.9 - 1.49E+06 - - - -4.1357 - 2.894 0.478 - 223.4 1 2 0 -0.0074 15 0 0 0 0.00E+00 1.03E+08 - - - 3.7647 1 221125_WJC_METTL3_EV_vs_WT_F08.15339.15339.2 9.83E-15 24/34 K.YVHYEIDAC[160.03]MDSEAPGSK[136.11].D "sp|Q86U44|MTA70_HUMAN,tr|H0YFV6|H0YFV6_HUMAN" 2 2078.8805 0.001 118593 15339 2 2078.87351 1040.4475 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 4.31 2703.7 - 1.51E+06 - - - -3.3585 - 4.478 0.812 - 1202.2 1 2 0 -0.007 18 0 0 0 0.00E+00 4.47E+07 - - - 8.722 1 221125_WJC_METTL3_EV_vs_WT_F08.15347.15347.4 1.05E-09 21/120 K.NIDDGTSDRPYSHALVAGIDR.Y "sp|P61353|RL27_HUMAN,tr|K7ELC7|K7ELC7_HUMAN" 2 2271.088 1.05 118595 15347 4 2271.085284 568.7793 60S ribosomal protein L27 OS=Homo sapiens OX=9606 GN=RPL27 PE=1 SV=2 4.56 2704.8 - 2.91E+06 - - - -1.1902 - 2.784 0.616 - 233.9 1 2 0 -0.0027 21 0 0 0 1.73E+08 1.64E+08 - - - 4.9255 0.9998 221125_WJC_METTL3_EV_vs_WT_F08.15355.15355.4 9.83E-05 22/96 R.LLASTLVHSVKKEQEFR.S "sp|Q9NYF8|BCLF1_HUMAN,tr|E9PKI6|E9PKI6_HUMAN,tr|A0A1W2PQ43|A0A1W2PQ43_HUMAN,tr|E9PK91|E9PK91_HUMAN,tr|E9PJA7|E9PJA7_HUMAN,tr|E9PK09|E9PK09_HUMAN,tr|E9PQN2|E9PQN2_HUMAN" 7 1984.1106 2.08 118598 15355 4 1984.104184 497.0349 Bcl-2-associated transcription factor 1 OS=Homo sapiens OX=9606 GN=BCLAF1 PE=1 SV=2 8.6 2705.8 - 1.01E+06 - - - -3.214 - 4.399 0.584 - 493.4 1 2 1 -0.0064 17 0 0 0 2.17E+07 1.04E+07 - - - 4.8217 1 221125_WJC_METTL3_EV_vs_WT_F08.15363.15363.3 7.18E-11 25/84 K.DHTPSQELALTQSVGGDSSADR.L "sp|Q86U44|MTA70_HUMAN,tr|H0YFV6|H0YFV6_HUMAN" 2 2270.0411 0.02 118600 15363 3 2271.029853 757.6876 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 4.22 2706.9 - 8.71E+06 - - - 435.5674 - 4.393 0.677 - 644.5 1 2 0 0.9888 22 0 0 0 2.81E+08 1.45E+10 - - - 9.3229 0.9999 221125_WJC_METTL3_EV_vs_WT_F08.15397.15397.4 1.00E-06 18/108 R.R[166.11]PGQSFHVNSEVNSVLSPR[166.11].S "sp|Q14671|PUM1_HUMAN,tr|Q5T1Z8|Q5T1Z8_HUMAN,tr|H0YEH2|H0YEH2_HUMAN,tr|Q5T1Z4|Q5T1Z4_HUMAN" 4 2129.0881 2.01 118614 15397 4 2129.082011 533.2793 Pumilio homolog 1 OS=Homo sapiens OX=9606 GN=PUM1 PE=1 SV=3 9.61 2711.3 - 949222 - - - -2.8547 - 3.211 0.503 - 216.3 1 2 0 -0.0061 19 0 0 0 3.77E+08 1.87E+08 - - - 3.9971 1 221125_WJC_METTL3_EV_vs_WT_F08.15399.15399.4 1.40E-09 21/108 R.RPGQSFHVNSEVNSVLSPR.S "sp|Q14671|PUM1_HUMAN,tr|Q5T1Z8|Q5T1Z8_HUMAN,tr|H0YEH2|H0YEH2_HUMAN,tr|Q5T1Z4|Q5T1Z4_HUMAN" 4 2109.0715 2.01 118615 15399 4 2109.06743 528.2752 Pumilio homolog 1 OS=Homo sapiens OX=9606 GN=PUM1 PE=1 SV=3 9.61 2711.5 - 1.82E+06 - - - -1.953 - 4.06 0.622 - 322.1 1 2 0 -0.0041 19 0 0 0 3.77E+08 1.87E+08 - - - 5.1127 0.9999 221125_WJC_METTL3_EV_vs_WT_F08.15405.15405.3 0.00104 18/60 R.ETNLDSLPLVDTHSKR.T sp|P08670|VIME_HUMAN 1 1823.9377 1.86 118617 15405 3 1823.932503 608.9865 Vimentin OS=Homo sapiens OX=9606 GN=VIM PE=1 SV=4 5.38 2712.3 - 1.35E+06 - - - -2.8718 - 3.204 0.44 - 398.6 1 2 0 -0.0052 16 0 0 0 8.29E+08 4.47E+08 - - - 6.4318 1 221125_WJC_METTL3_EV_vs_WT_F08.15407.15407.3 1.93E-09 17/72 K.LHISPSNMTNQNTNEYLEK.L sp|Q13547|HDAC1_HUMAN 1 2232.0481 5.11 118619 15407 3 2232.043921 745.0233 Histone deacetylase 1 OS=Homo sapiens OX=9606 GN=HDAC1 PE=1 SV=1 5.4 2712.5 - 1.08E+06 - - - -1.8705 - 2.993 0.529 - 303.1 1 2 0 -0.0042 19 0 0 0 3.70E+07 7.23E+06 - - - 7.13 1 221125_WJC_METTL3_EV_vs_WT_F08.15411.15411.4 3.99E-06 18/90 R.ETNLDSLPLVDTHSK[136.11]R[166.11].T sp|P08670|VIME_HUMAN 1 1841.9602 1.81 118621 15411 4 1841.955811 461.4973 Vimentin OS=Homo sapiens OX=9606 GN=VIM PE=1 SV=4 5.38 2713 - 1.66E+06 - - - -2.3888 - 3.147 0.53 - 331.4 1 2 0 -0.0044 16 0 0 0 1.38E+09 7.61E+08 - - - 4.2417 1 221125_WJC_METTL3_EV_vs_WT_F08.15413.15413.3 1.64E-09 23/72 R.R[166.11]PGQSFHVNSEVNSVLSPR[166.11].S "sp|Q14671|PUM1_HUMAN,tr|Q5T1Z8|Q5T1Z8_HUMAN,tr|H0YEH2|H0YEH2_HUMAN,tr|Q5T1Z4|Q5T1Z4_HUMAN" 4 2129.0881 2.19 118623 15413 3 2129.083202 710.7033 Pumilio homolog 1 OS=Homo sapiens OX=9606 GN=PUM1 PE=1 SV=3 9.61 2713.3 - 767118 - - - -2.2953 - 3.878 0.551 - 667.7 1 2 0 -0.0049 19 0 0 0 2.66E+08 1.22E+08 - - - 8.0115 0.9999 221125_WJC_METTL3_EV_vs_WT_F08.15419.15419.4 2.28E-09 18/114 R.AGIK[136.11]VTVAGLAGK[136.11]DPVQC[160.03]SR[166.11].D "sp|Q99497|PARK7_HUMAN,tr|K7ELW0|K7ELW0_HUMAN" 2 2052.136 2.76 118626 15419 4 2052.131776 514.0413 Parkinson disease protein 7 OS=Homo sapiens OX=9606 GN=PARK7 PE=1 SV=2 9.32 2714 - 674170 - - - -2.0652 - 3.485 0.578 - 179 1 2 2 -0.0042 20 0 0 0 2.67E+07 9.67E+06 - - - 4.6731 0.9999 221125_WJC_METTL3_EV_vs_WT_F08.15420.15420.4 3.23E-07 18/120 R.SMGETESGDAFLDLKKPPASK.C "sp|Q9NRA8|4ET_HUMAN,tr|B1AKL6|B1AKL6_HUMAN,tr|B1AKL5|B1AKL5_HUMAN,tr|B1AKL4|B1AKL4_HUMAN" 4 2207.078 1.2 118627 15420 4 2207.0749 552.7768 Eukaryotic translation initiation factor 4E transporter OS=Homo sapiens OX=9606 GN=EIF4ENIF1 PE=1 SV=2 4.78 2714.2 - 712026 - - - -1.4046 - 3.29 0.536 - 282.1 1 2 1 -0.0031 21 0 0 0 1.84E+07 1.53E+07 - - - 4.2842 1 221125_WJC_METTL3_EV_vs_WT_F08.15427.15427.3 1.27E-11 25/76 R.AGIKVTVAGLAGKDPVQC[160.03]SR.D "sp|Q99497|PARK7_HUMAN,tr|K7ELW0|K7ELW0_HUMAN" 2 2026.0993 3.44 118631 15427 3 2026.095468 676.3737 Parkinson disease protein 7 OS=Homo sapiens OX=9606 GN=PARK7 PE=1 SV=2 9.32 2715 - 957915 - - - -1.913 - 4.475 0.68 - 568.6 1 2 2 -0.0039 20 0 0 0 1.24E+07 3.60E+06 - - - 9.7557 1 221125_WJC_METTL3_EV_vs_WT_F08.15428.15428.2 6.85E-10 17/32 R.ISIGGGSC[160.03]AISGGYGSR.A "sp|P48668|K2C6C_HUMAN,sp|P04259|K2C6B_HUMAN,sp|P02538|K2C6A_HUMAN" 3 1597.7519 999 118632 15428 2 1597.746933 799.8832 "Keratin, type II cytoskeletal 6C OS=Homo sapiens OX=9606 GN=KRT6C PE=1 SV=3" 8.22 2715.1 - 770784 - - - -3.0806 - 3.576 0.639 - 1027 1 2 0 -0.0049 17 0 0 0 1.94E+07 0.00E+00 - - - 6.8919 1 221125_WJC_METTL3_EV_vs_WT_F08.15431.15431.3 3.89E-06 13/116 K.VASGVLSPPPAAPPPSSSSVPEAGGPPIKK.Q "sp|Q8IXM2|BAP18_HUMAN,tr|H0YIS7|H0YIS7_HUMAN,tr|F8W038|F8W038_HUMAN,tr|F8W1H0|F8W1H0_HUMAN" 4 2777.4963 5.24 118635 15431 3 2777.495735 926.8394 Chromatin complexes subunit BAP18 OS=Homo sapiens OX=9606 GN=BAP18 PE=1 SV=1 8.56 2715.5 - 451762 - - - -0.22 - 2.545 0.536 - 117.9 1 2 0 -0.0006 30 0 0 0 8.85E+06 1.69E+06 - - - 6.6648 1 221125_WJC_METTL3_EV_vs_WT_F08.15438.15438.3 4.44E-06 19/60 R.ETNLDSLPLVDTHSK[136.11]R[166.11].T sp|P08670|VIME_HUMAN 1 1841.9602 1.86 118639 15438 3 1841.957874 614.994 Vimentin OS=Homo sapiens OX=9606 GN=VIM PE=1 SV=4 5.38 2716.3 - 2.11E+06 - - - -1.2688 - 3.212 0.567 - 477 1 2 0 -0.0023 16 0 0 0 8.28E+08 4.47E+08 - - - 7.8549 0.9966 221125_WJC_METTL3_EV_vs_WT_F08.15439.15439.3 0.0141 Aug-44 R.GQPIYIQFSNHK[136.11].E "sp|P26599|PTBP1_HUMAN,tr|A0A6Q8PEX4|A0A6Q8PEX4_HUMAN,tr|A0A0U1RRM4|A0A0U1RRM4_HUMAN,tr|A6NLN1|A6NLN1_HUMAN,tr|K7EKJ7|K7EKJ7_HUMAN,tr|K7ES59|K7ES59_HUMAN,tr|A0A7I2V4H6|A0A7I2V4H6_HUMAN,tr|A0A7I2V621|A0A7I2V621_HUMAN" 8 1438.7448 0.72 118640 15439 3 1438.739944 480.5889 Polypyrimidine tract-binding protein 1 OS=Homo sapiens OX=9606 GN=PTBP1 PE=1 SV=1 8.6 2716.4 - 398854 - - - -3.4092 - 1.565 0.343 - 80.7 1 2 0 -0.0049 12 0 0 0 8.42E+06 1.16E+07 - - - 3.6042 0.988 221125_WJC_METTL3_EV_vs_WT_F08.15440.15440.4 0.0155 Nov-84 K.GFSLLATEDKEALKK.Q "sp|P09874|PARP1_HUMAN,tr|A0A7I2V5E9|A0A7I2V5E9_HUMAN,tr|A0A7I2V625|A0A7I2V625_HUMAN,tr|A0A7I2V3E1|A0A7I2V3E1_HUMAN" 4 1648.9036 1.01 118641 15440 4 1648.901822 413.2332 Poly [ADP-ribose] polymerase 1 OS=Homo sapiens OX=9606 GN=PARP1 PE=1 SV=4 6.18 2716.6 - 311061 - - - -1.0704 - 1.495 0.257 - 41.5 1 2 1 -0.0018 15 0 0 0 4.48E+06 4.42E+06 - - - 1.6063 0.9976 221125_WJC_METTL3_EV_vs_WT_F08.15443.15443.3 0.0163 Aug-56 R.ADTQTYQPYNKDWIK.E sp|P84090|ERH_HUMAN 1 1869.8897 3.04 118642 15443 3 1869.890182 624.3039 Enhancer of rudimentary homolog OS=Homo sapiens OX=9606 GN=ERH PE=1 SV=1 6 2717 - 628740 - - - 0.2428 - 1.719 0.344 - 73.5 1 2 1 0.0005 15 0 0 0 1.79E+08 5.90E+07 - - - 3.7887 1 221125_WJC_METTL3_EV_vs_WT_F08.15447.15447.3 6.60E-09 26/72 R.RPGQSFHVNSEVNSVLSPR.S "sp|Q14671|PUM1_HUMAN,tr|Q5T1Z8|Q5T1Z8_HUMAN,tr|H0YEH2|H0YEH2_HUMAN,tr|Q5T1Z4|Q5T1Z4_HUMAN" 4 2109.0715 2.46 118645 15447 3 2109.07167 704.0311 Pumilio homolog 1 OS=Homo sapiens OX=9606 GN=PUM1 PE=1 SV=3 9.61 2717.4 - 4.15E+06 - - - 0.0574 - 4.304 0.613 - 955.9 1 2 0 0.0001 19 0 0 0 7.72E+07 3.14E+07 - - - 8.9601 0.9999 221125_WJC_METTL3_EV_vs_WT_F08.15449.15449.3 2.21E-05 15/72 R.GQTTLPFR[166.11]PVTQEEDDDQR[166.11].- sp|Q96SB8|SMC6_HUMAN 1 2251.062 2.24 118647 15449 3 2251.065773 751.3613 Structural maintenance of chromosomes protein 6 OS=Homo sapiens OX=9606 GN=SMC6 PE=1 SV=2 4.11 2717.6 - 744883 - - - 1.6788 - 2.549 0.421 - 203.4 1 2 0 0.0038 19 0 0 0 2.64E+07 1.18E+07 - - - 5.5315 1 221125_WJC_METTL3_EV_vs_WT_F08.15459.15459.2 1.60E-06 13/24 R.FSGSGSGTDFTLK.L "sp|A2NJV5|KV229_HUMAN,sp|A0A087WW87|KV240_HUMAN,sp|P06310|KV230_HUMAN,sp|A0A075B6S2|KVD29_HUMAN,sp|P01614|KVD40_HUMAN,sp|P01615|KVD28_HUMAN,sp|A0A075B6S6|KVD30_HUMAN,sp|A0A075B6P5|KV228_HUMAN,sp|A0A0A0MRZ7|KVD26_HUMAN" 9 1302.6092 2374.29 118655 15459 2 1302.606984 652.3119 Immunoglobulin kappa variable 2-29 OS=Homo sapiens OX=9606 GN=IGKV2-29 PE=3 SV=2 5.84 2718.8 - 447521 - - - -1.6981 - 2.584 0.594 - 323.2 1 2 0 -0.0022 13 0 0 0 6.66E+08 2.80E+05 - - - 5.8641 0.9999 221125_WJC_METTL3_EV_vs_WT_F08.15460.15460.3 5.32E-09 Dec-88 K.TPVK[136.11]EPNSENVDISSGGGVTGWK[136.11].S sp|P61026|RAB10_HUMAN 1 2373.1783 1.36 118656 15460 3 2373.174462 792.0667 Ras-related protein Rab-10 OS=Homo sapiens OX=9606 GN=RAB10 PE=1 SV=1 4.68 2718.9 - 298302 - - - -1.6252 - 2.689 0.6 - 118.3 1 2 1 -0.0039 23 0 0 0 5.79E+06 4.27E+06 - - - 7.5489 0.8511 221125_WJC_METTL3_EV_vs_WT_F08.15465.15465.4 0.0862 8/108 K.VAVEWDKDHGVLESHLAEK.G "sp|Q8WVQ1|CANT1_HUMAN,tr|K7EN15|K7EN15_HUMAN" 2 2161.0804 3.36 118659 15465 4 2161.084119 541.2774 Soluble calcium-activated nucleotidase 1 OS=Homo sapiens OX=9606 GN=CANT1 PE=1 SV=1 4.86 2719.5 - 981592 - - - 1.7288 - 1.866 0.195 - 29.2 3 2 1 0.0037 19 0 0 0 2.39E+07 7.13E+06 - - - 0.7696 0.9739 221125_WJC_METTL3_EV_vs_WT_F08.15474.15474.2 0.1 16-Dec L.PLVDTHSK[136.11]R[166.11].T sp|P08670|VIME_HUMAN 1 1069.5999 1.74 118666 15474 2 1069.598595 535.8072 Vimentin OS=Homo sapiens OX=9606 GN=VIM PE=1 SV=4 9.18 2720.7 - 812688 - - - -1.2322 - 2.159 0.296 - 588.8 1 1 0 -0.0013 9 0 0 0 1.52E+08 8.69E+07 - - - 3.4535 0.9931 221125_WJC_METTL3_EV_vs_WT_F08.15475.15475.4 0.000989 17/102 R.R[166.11]PEHGGPPELFYDETEAR[166.11].K "sp|O43709|BUD23_HUMAN,tr|F8WD87|F8WD87_HUMAN,tr|F8WD67|F8WD67_HUMAN,tr|E9PCQ7|E9PCQ7_HUMAN" 4 2118.9874 0.2 118667 15475 4 2119.002184 530.7541 Probable 18S rRNA (guanine-N(7))-methyltransferase OS=Homo sapiens OX=9606 GN=BUD23 PE=1 SV=2 4.57 2720.8 - 789750 - - - 6.9901 - 3.354 0.384 - 229.9 1 2 0 0.0148 18 0 0 0 4.26E+06 2.13E+07 - - - 2.9788 1 221125_WJC_METTL3_EV_vs_WT_F08.15484.15484.3 5.69E-06 16/68 K.YVHYEIDAC[160.03]MDSEAPGSK[136.11].D "sp|Q86U44|MTA70_HUMAN,tr|H0YFV6|H0YFV6_HUMAN" 2 2078.8805 0.001 118674 15484 3 2078.875026 693.9674 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 4.31 2721.9 - 753997 - - - -2.6293 - 3.055 0.584 - 297.4 1 2 0 -0.0055 18 0 0 0 0.00E+00 2.13E+07 - - - 7.8304 0.9998 221125_WJC_METTL3_EV_vs_WT_F08.15486.15486.4 2.07E-07 16/96 R.AQSPGAVEEILDR[166.11]ENK[136.11]R[166.11].M "sp|Q9NYM9|BET1L_HUMAN,tr|A0A0C4DH16|A0A0C4DH16_HUMAN,tr|B8ZZS0|B8ZZS0_HUMAN,tr|E9PHY4|E9PHY4_HUMAN,tr|H7BXT7|H7BXT7_HUMAN" 5 1939.0117 1.36 118676 15486 4 1939.008005 485.7602 BET1-like protein OS=Homo sapiens OX=9606 GN=BET1L PE=1 SV=1 4.87 2722.2 - 568010 - - - -1.9278 - 2.793 0.48 - 281.2 1 2 1 -0.0037 17 0 0 0 1.48E+07 1.09E+07 - - - 3.7595 0.9997 221125_WJC_METTL3_EV_vs_WT_F08.15487.15487.4 9.11E-05 19/96 R.AQSPGAVEEILDRENKR.M "sp|Q9NYM9|BET1L_HUMAN,tr|A0A0C4DH16|A0A0C4DH16_HUMAN,tr|B8ZZS0|B8ZZS0_HUMAN,tr|E9PHY4|E9PHY4_HUMAN,tr|H7BXT7|H7BXT7_HUMAN" 5 1910.981 1.15 118677 15487 4 1910.981233 478.7525 BET1-like protein OS=Homo sapiens OX=9606 GN=BET1L PE=1 SV=1 4.87 2722.3 - 530950 - - - 0.1204 - 3.237 0.423 - 391.8 1 2 1 0.0002 17 0 0 0 1.50E+07 1.30E+07 - - - 3.3156 1 221125_WJC_METTL3_EV_vs_WT_F08.15493.15493.4 5.58E-08 18/96 K.ELEGWEPDDDPIEEHKK.H "sp|O15392|BIRC5_HUMAN,tr|A0A0B4J1S3|A0A0B4J1S3_HUMAN" 2 2064.9276 2.62 118682 15493 4 2064.923949 517.2392 Baculoviral IAP repeat-containing protein 5 OS=Homo sapiens OX=9606 GN=BIRC5 PE=1 SV=3 4.12 2722.9 - 1.03E+06 - - - -1.7826 - 2.893 0.58 - 273.2 1 2 0 -0.0037 17 0 0 0 9.98E+07 3.81E+07 - - - 4.6421 0.9989 221125_WJC_METTL3_EV_vs_WT_F08.15496.15496.2 0.00015 28-Dec R.ADTQTYQPYNKDWIK.E sp|P84090|ERH_HUMAN 1 1869.8897 7.09 118685 15496 2 1869.888661 935.9521 Enhancer of rudimentary homolog OS=Homo sapiens OX=9606 GN=ERH PE=1 SV=1 6 2723.3 - 293813 - - - -0.5706 - 2.652 0.527 - 326.6 1 2 1 -0.0011 15 0 0 0 3.62E+06 5.11E+05 - - - 5.3309 0.9999 221125_WJC_METTL3_EV_vs_WT_F08.15499.15499.4 2.78E-09 19/114 K.FVIKRPELLTHSTTEVTQPR.T "sp|P78347|GTF2I_HUMAN,tr|A0A494C0Q7|A0A494C0Q7_HUMAN,tr|A0A494C1K3|A0A494C1K3_HUMAN" 3 2351.2961 1.54 118686 15499 4 2351.297069 588.8313 General transcription factor II-I OS=Homo sapiens OX=9606 GN=GTF2I PE=1 SV=2 8.75 2723.7 - 1.12E+06 - - - 0.3994 - 3.221 0.59 - 232.4 1 2 1 0.0009 20 0 0 0 1.97E+07 1.28E+07 - - - 4.7522 0.9969 221125_WJC_METTL3_EV_vs_WT_F08.15501.15501.3 1.53E-06 14/64 M.QTHISDTSVVLSMDNNR.N "sp|P48668|K2C6C_HUMAN,sp|P04259|K2C6B_HUMAN,sp|P02538|K2C6A_HUMAN" 3 1915.9058 69.14 118688 15501 3 1915.907446 639.6425 "Keratin, type II cytoskeletal 6C OS=Homo sapiens OX=9606 GN=KRT6C PE=1 SV=3" 5.21 2724 - 464115 - - - 0.8649 - 2.655 0.499 - 261.7 1 1 0 0.0017 17 0 0 0 6.67E+06 9.65E+04 - - - 6.5697 0.9999 221125_WJC_METTL3_EV_vs_WT_F08.15508.15508.4 1.12E-06 20/108 R.SFFHQHYLGGQEPTPSNIR.M "sp|P46379|BAG6_HUMAN,tr|A0A7I2V508|A0A7I2V508_HUMAN,tr|A0A7P0MQS5|A0A7P0MQS5_HUMAN,tr|A0A0G2JL47|A0A0G2JL47_HUMAN,tr|A0A024RCR6|A0A024RCR6_HUMAN,tr|A0A0G2JK23|A0A0G2JK23_HUMAN" 6 2214.0606 1.71 118693 15508 4 2214.06637 554.5224 Large proline-rich protein BAG6 OS=Homo sapiens OX=9606 GN=BAG6 PE=1 SV=2 6.66 2724.8 - 531961 - - - 2.5835 - 3.025 0.523 - 238 1 2 0 0.0057 19 0 0 0 3.01E+07 1.76E+07 - - - 4.1511 1 221125_WJC_METTL3_EV_vs_WT_F08.15509.15509.4 3.53E-07 16/96 K.ELEGWEPDDDPIEEHK[136.11]K[136.11].H "sp|O15392|BIRC5_HUMAN,tr|A0A0B4J1S3|A0A0B4J1S3_HUMAN" 2 2080.956 2.62 118694 15509 4 2080.953373 521.2463 Baculoviral IAP repeat-containing protein 5 OS=Homo sapiens OX=9606 GN=BIRC5 PE=1 SV=3 4.12 2724.9 - 819707 - - - -1.2768 - 3.327 0.525 - 188.6 1 2 0 -0.0027 17 0 0 0 9.98E+07 3.81E+07 - - - 4.2122 0.9999 221125_WJC_METTL3_EV_vs_WT_F08.15513.15513.3 0.000649 Dec-40 R.NPEAALSPTFR[166.11].S "sp|Q86U44|MTA70_HUMAN,tr|B4E349|B4E349_HUMAN,tr|F5H6D8|F5H6D8_HUMAN,tr|B4DTN4|B4DTN4_HUMAN" 4 1211.6174 0.02 118698 15513 3 1211.61614 404.8797 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 6 2725.4 - 328804 - - - -1.0457 - 2.287 0.384 - 310.4 1 2 0 -0.0013 11 0 0 0 6.26E+05 2.65E+07 - - - 5.1709 1 221125_WJC_METTL3_EV_vs_WT_F08.15517.15517.3 1.63E-05 18/64 K.ELEGWEPDDDPIEEHKK.H "sp|O15392|BIRC5_HUMAN,tr|A0A0B4J1S3|A0A0B4J1S3_HUMAN" 2 2064.9276 3.88 118700 15517 3 2064.927631 689.3165 Baculoviral IAP repeat-containing protein 5 OS=Homo sapiens OX=9606 GN=BIRC5 PE=1 SV=3 4.12 2725.9 - 1.17E+06 - - - 0.0005 - 2.816 0.525 - 373.7 1 2 0 0 17 0 0 0 6.15E+07 1.58E+07 - - - 7.0088 1 221125_WJC_METTL3_EV_vs_WT_F08.15518.15518.4 1.65E-08 24/108 R.SFFHQHYLGGQEPTPSNIR[166.11].M "sp|P46379|BAG6_HUMAN,tr|A0A7I2V508|A0A7I2V508_HUMAN,tr|A0A7P0MQS5|A0A7P0MQS5_HUMAN,tr|A0A0G2JL47|A0A0G2JL47_HUMAN,tr|A0A024RCR6|A0A024RCR6_HUMAN,tr|A0A0G2JK23|A0A0G2JK23_HUMAN" 6 2224.0689 1.71 118701 15518 4 2224.069519 557.0245 Large proline-rich protein BAG6 OS=Homo sapiens OX=9606 GN=BAG6 PE=1 SV=2 6.66 2726 - 978232 - - - 0.2693 - 3.428 0.542 - 325.4 1 2 0 0.0006 19 0 0 0 3.01E+07 1.76E+07 - - - 4.3602 0.9999 221125_WJC_METTL3_EV_vs_WT_F08.15526.15526.3 6.23E-06 19/72 R.SFFHQHYLGGQEPTPSNIR[166.11].M "sp|P46379|BAG6_HUMAN,tr|A0A7I2V508|A0A7I2V508_HUMAN,tr|A0A7P0MQS5|A0A7P0MQS5_HUMAN,tr|A0A0G2JL47|A0A0G2JL47_HUMAN,tr|A0A024RCR6|A0A024RCR6_HUMAN,tr|A0A0G2JK23|A0A0G2JK23_HUMAN" 6 2224.0689 2.2 118706 15526 3 2224.064162 742.3636 Large proline-rich protein BAG6 OS=Homo sapiens OX=9606 GN=BAG6 PE=1 SV=2 6.66 2727 - 447081 - - - -2.1393 - 2.611 0.489 - 244.6 1 2 0 -0.0048 19 0 0 0 1.70E+07 7.73E+06 - - - 6.3484 1 221125_WJC_METTL3_EV_vs_WT_F08.15527.15527.2 9.02E-09 15/30 R.ETNLDSLPLVDTHSKR.T sp|P08670|VIME_HUMAN 1 1823.9377 2.33 118707 15527 2 1823.934766 912.9761 Vimentin OS=Homo sapiens OX=9606 GN=VIM PE=1 SV=4 5.38 2727.1 - 369077 - - - -1.6311 - 2.81 0.658 - 408.3 1 2 0 -0.003 16 0 0 0 1.85E+07 7.92E+06 - - - 6.4402 1 221125_WJC_METTL3_EV_vs_WT_F08.15535.15535.3 3.71E-08 16/68 R.K[136.11]DTEAGETFSSVQANLSK[136.11].A "sp|P35251|RFC1_HUMAN,tr|A0A1W2PP02|A0A1W2PP02_HUMAN" 2 1926.9506 0.69 118712 15535 3 1926.950363 643.3241 Replication factor C subunit 1 OS=Homo sapiens OX=9606 GN=RFC1 PE=1 SV=4 4.68 2728 - 549621 - - - -0.0976 - 3.204 0.579 - 401 1 2 0 -0.0002 18 0 0 0 6.49E+06 9.40E+06 - - - 7.8947 1 221125_WJC_METTL3_EV_vs_WT_F08.15536.15536.4 8.55E-08 15/102 K.K[136.11]VTHAVVTVPAYFNDAQR[166.11].Q "sp|P11021|BIP_HUMAN,tr|A0A7P0TB36|A0A7P0TB36_HUMAN,tr|A0A7P0TAI0|A0A7P0TAI0_HUMAN" 3 2033.0813 0.49 118713 15536 4 2033.079093 509.2776 Endoplasmic reticulum chaperone BiP OS=Homo sapiens OX=9606 GN=HSPA5 PE=1 SV=2 8.6 2728.2 - 471465 - - - -1.0998 - 3.289 0.545 - 181.6 1 2 0 -0.0022 18 0 0 0 1.94E+07 3.93E+07 - - - 4.3769 1 221125_WJC_METTL3_EV_vs_WT_F08.15540.15540.4 2.25E-06 17/90 R.ETNLDSLPLVDTHSKR.T sp|P08670|VIME_HUMAN 1 1823.9377 1.82 118715 15540 4 1823.937461 456.9917 Vimentin OS=Homo sapiens OX=9606 GN=VIM PE=1 SV=4 5.38 2728.7 - 3.76E+07 - - - -0.1535 - 3.375 0.54 - 371 1 2 0 -0.0003 16 0 0 0 1.38E+09 7.61E+08 - - - 4.3546 1 221125_WJC_METTL3_EV_vs_WT_F08.15541.15541.3 4.37E-16 21/92 R.VLFRPSDTANSSNQDALSSNTSLK.L sp|Q8N4V1|EMC5_HUMAN 1 2551.2514 1.21 118716 15541 3 2551.249333 851.4244 ER membrane protein complex subunit 5 OS=Homo sapiens OX=9606 GN=MMGT1 PE=1 SV=1 5.93 2728.8 - 618531 - - - -0.8196 - 4.45 0.723 - 501.6 1 2 0 -0.0021 24 0 0 0 1.67E+07 1.38E+07 - - - 10.0676 1 221125_WJC_METTL3_EV_vs_WT_F08.15543.15543.3 4.52E-13 21/92 R.VLFR[166.11]PSDTANSSNQDALSSNTSLK[136.11].L sp|Q8N4V1|EMC5_HUMAN 1 2569.2739 1.21 118718 15543 3 2569.268097 857.4319 ER membrane protein complex subunit 5 OS=Homo sapiens OX=9606 GN=MMGT1 PE=1 SV=1 5.93 2729.1 - 613449 - - - -2.2563 - 4.077 0.647 - 535.9 1 2 0 -0.0058 24 0 0 0 1.67E+07 1.38E+07 - - - 9.0159 1 221125_WJC_METTL3_EV_vs_WT_F08.15546.15546.3 1.03E-05 16/56 R.STSHK[136.11]PDEIYGMIER[166.11].L sp|Q86U44|MTA70_HUMAN 1 1779.8581 0.11 118719 15546 3 1779.857958 594.2933 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 5.42 2729.5 - 1.56E+06 - - - -0.0539 - 2.88 0.483 - 349 1 2 0 -0.0001 15 0 0 0 9.62E+06 8.62E+07 - - - 6.6851 0.7988 221125_WJC_METTL3_EV_vs_WT_F08.15550.15550.2 1.95 20-Sep K.ISQR[166.11]DENGELR[166.11].L sp|O15355|PPM1G_HUMAN 1 1335.6646 0.01 118723 15550 2 1335.666334 668.8396 Protein phosphatase 1G OS=Homo sapiens OX=9606 GN=PPM1G PE=1 SV=1 4.68 2729.9 - 516609 - - - 1.3125 - 1.259 0.097 - 124.8 1 2 1 0.0018 11 0 0 0 1.83E+05 1.89E+07 - - - 0.38 1 221125_WJC_METTL3_EV_vs_WT_F08.15553.15553.4 2.11E-08 23/132 K.TTGTPPDSSLVTYELHSRPEQDK.F "sp|Q13561|DCTN2_HUMAN,tr|H0YI98|H0YI98_HUMAN,tr|A8K8J9|A8K8J9_HUMAN,tr|A0A7I2V5R4|A0A7I2V5R4_HUMAN,tr|F8W1I6|F8W1I6_HUMAN,tr|A0A7I2V4H4|A0A7I2V4H4_HUMAN,tr|A0A7I2V390|A0A7I2V390_HUMAN,tr|A0A7I2V4Y9|A0A7I2V4Y9_HUMAN,tr|F8VW18|F8VW18_HUMAN" 9 2557.2296 1.27 118724 15553 4 2557.228541 640.3147 Dynactin subunit 2 OS=Homo sapiens OX=9606 GN=DCTN2 PE=1 SV=4 4.75 2730.3 - 702178 - - - -0.4243 - 4.098 0.596 - 382.3 1 2 0 -0.0011 23 0 0 0 3.17E+07 2.50E+07 - - - 4.8703 1 221125_WJC_METTL3_EV_vs_WT_F08.15560.15560.3 5.20E-12 19/84 R.GNNNVMSNYEAYKPSTGAMGDR.L "sp|Q86XP3|DDX42_HUMAN,tr|A0A0A0MSJ0|A0A0A0MSJ0_HUMAN" 2 2375.027 1.99 118729 15560 3 2375.029289 792.683 ATP-dependent RNA helicase DDX42 OS=Homo sapiens OX=9606 GN=DDX42 PE=1 SV=1 6.07 2731.2 - 348912 - - - 0.9457 - 3.541 0.693 - 237.4 1 2 0 0.0022 22 0 0 0 8.54E+06 4.30E+06 - - - 9.2633 0.9999 221125_WJC_METTL3_EV_vs_WT_F08.15562.15562.3 1.35E-06 13/64 K.ELEGWEPDDDPIEEHK[136.11]K[136.11].H "sp|O15392|BIRC5_HUMAN,tr|A0A0B4J1S3|A0A0B4J1S3_HUMAN" 2 2080.956 3.92 118731 15562 3 2080.962161 694.6593 Baculoviral IAP repeat-containing protein 5 OS=Homo sapiens OX=9606 GN=BIRC5 PE=1 SV=3 4.12 2731.4 - 716828 - - - 2.9462 - 2.674 0.506 - 178.7 1 2 0 0.0061 17 0 0 0 6.07E+07 1.55E+07 - - - 6.6645 0.9734 221125_WJC_METTL3_EV_vs_WT_F08.15564.15564.2 0.000483 14-Sep P.LVDTHSKR.T sp|P08670|VIME_HUMAN 1 954.5247 1.81 118733 15564 2 954.524328 478.2696 Vimentin OS=Homo sapiens OX=9606 GN=VIM PE=1 SV=4 8.75 2731.7 - 452397 - - - -0.3677 - 1.699 0.337 - 256.3 1 1 0 -0.0003 8 0 0 0 1.43E+07 7.93E+06 - - - 3.1285 1 221125_WJC_METTL3_EV_vs_WT_F08.15572.15572.3 7.05E-09 24/100 K.AADR[166.11]LPNLSSPSAEGPPGPPSGPAPR[166.11].K sp|O60784|TOM1_HUMAN 1 2514.273 1.74 118739 15572 3 2514.277308 839.0983 Target of Myb protein 1 OS=Homo sapiens OX=9606 GN=TOM1 PE=1 SV=2 6.12 2732.7 - 283257 - - - 1.7174 - 3.948 0.623 - 461.8 1 2 1 0.0043 26 0 0 0 6.61E+06 3.81E+06 - - - 8.6439 1 221125_WJC_METTL3_EV_vs_WT_F08.15576.15576.4 0.000114 15/84 R.STSHK[136.11]PDEIYGMIER[166.11].L sp|Q86U44|MTA70_HUMAN 1 1779.8581 0.01 118741 15576 4 1779.858641 445.9718 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 5.42 2733.3 - 1.11E+06 - - - 0.3298 - 2.742 0.499 - 171.5 1 2 0 0.0006 15 0 0 0 4.39E+05 5.06E+07 - - - 3.9301 0.9993 221125_WJC_METTL3_EV_vs_WT_F08.15578.15578.4 0.000452 15/108 R.VEEKEPEVTISSIRPISER.A "sp|Q8N6H7|ARFG2_HUMAN,tr|E9PMU9|E9PMU9_HUMAN,tr|E9PQP3|E9PQP3_HUMAN,tr|H0YDN9|H0YDN9_HUMAN,tr|G5E9L0|G5E9L0_HUMAN,tr|A0A0D9SF70|A0A0D9SF70_HUMAN" 6 2197.159 0.68 118743 15578 4 2197.157068 550.297 ADP-ribosylation factor GTPase-activating protein 2 OS=Homo sapiens OX=9606 GN=ARFGAP2 PE=1 SV=1 4.65 2733.5 - 399260 - - - -0.8916 - 2.071 0.393 - 128.9 1 2 1 -0.002 19 0 0 0 2.45E+07 3.62E+07 - - - 2.8924 0.9999 221125_WJC_METTL3_EV_vs_WT_F08.15579.15579.4 7.38E-06 15/108 R.RGHVTQDAPIPGSPLYTIK.A sp|Q15029|U5S1_HUMAN 1 2049.1007 3.05 118744 15579 4 2049.104571 513.2825 116 kDa U5 small nuclear ribonucleoprotein component OS=Homo sapiens OX=9606 GN=EFTUD2 PE=1 SV=1 8.6 2733.6 - 268803 - - - 1.8774 - 2.698 0.466 - 142.7 1 2 0 0.0038 19 0 0 0 6.32E+06 2.07E+06 - - - 3.6167 1 221125_WJC_METTL3_EV_vs_WT_F08.15583.15583.3 6.54E-10 15/68 K.K[136.11]VTHAVVTVPAYFNDAQR[166.11].Q "sp|P11021|BIP_HUMAN,tr|A0A7P0TB36|A0A7P0TB36_HUMAN,tr|A0A7P0TAI0|A0A7P0TAI0_HUMAN" 3 2033.0813 0.58 118746 15583 3 2033.081459 678.7011 Endoplasmic reticulum chaperone BiP OS=Homo sapiens OX=9606 GN=HSPA5 PE=1 SV=2 8.6 2734.1 - 514162 - - - 0.0639 - 3.332 0.611 - 289.4 1 2 0 0.0001 18 0 0 0 1.54E+07 2.67E+07 - - - 8.349 0.9887 221125_WJC_METTL3_EV_vs_WT_F08.15586.15586.3 0.00128 Oct-40 E.PDDDPIEEHKK.H "sp|O15392|BIRC5_HUMAN,tr|A0A0B4J1S3|A0A0B4J1S3_HUMAN" 2 1321.615 3.3 118749 15586 3 1321.613495 441.5456 Baculoviral IAP repeat-containing protein 5 OS=Homo sapiens OX=9606 GN=BIRC5 PE=1 SV=3 4.43 2734.5 - 175030 - - - -1.1463 - 1.61 0.474 - 133.8 1 1 0 -0.0015 11 0 0 0 2.51E+06 7.61E+05 - - - 5.1771 0.9999 221125_WJC_METTL3_EV_vs_WT_F08.15590.15590.4 9.94E-07 15/102 K.QFTPC[160.03]QLLADHANSPNK[136.11]K[136.11].F "sp|P40939|ECHA_HUMAN,tr|H0YFD6|H0YFD6_HUMAN,tr|A0A2R8Y4F5|A0A2R8Y4F5_HUMAN" 3 2084.0444 0.95 118751 15590 4 2084.050268 522.0184 "Trifunctional enzyme subunit alpha, mitochondrial OS=Homo sapiens OX=9606 GN=HADHA PE=1 SV=2" 8.21 2735.1 - 906942 - - - 2.8114 - 2.751 0.495 - 209.4 1 2 0 0.0059 18 0 0 0 1.99E+07 2.09E+07 - - - 3.8795 1 221125_WJC_METTL3_EV_vs_WT_F08.15591.15591.3 2.16E-07 13/60 R.HSIAQLDPEALGNIKK.L sp|Q53HL2|BOREA_HUMAN 1 1732.9472 1.05 118752 15591 3 1732.945974 578.6563 Borealin OS=Homo sapiens OX=9606 GN=CDCA8 PE=1 SV=2 6.75 2735.2 - 259995 - - - -0.6982 - 2.823 0.575 - 286.2 1 2 0 -0.0012 16 0 0 0 1.14E+07 1.08E+07 - - - 7.6132 0.9999 221125_WJC_METTL3_EV_vs_WT_F08.15594.15594.4 0.000785 Dec-96 K.RPPENEAPPVPFLHAQR.Y "sp|Q969N2|PIGT_HUMAN,tr|A0A1W2PRZ8|A0A1W2PRZ8_HUMAN,tr|A0A1W2PP53|A0A1W2PP53_HUMAN,tr|A0A1W2PPR6|A0A1W2PPR6_HUMAN,tr|A0A1W2PPS0|A0A1W2PPS0_HUMAN,tr|A0A1W2PQ52|A0A1W2PQ52_HUMAN,tr|A0A1W2PNP0|A0A1W2PNP0_HUMAN,tr|A0A1W2PP57|A0A1W2PP57_HUMAN,tr|A0A1W2PPQ7|A0A1W2PPQ7_HUMAN,tr|A0A1W2PQY1|A0A1W2PQY1_HUMAN,tr|A0A1W2PP13|A0A1W2PP13_HUMAN,tr|A0A1W2PSC5|A0A1W2PSC5_HUMAN,tr|A0A1W2PQN1|A0A1W2PQN1_HUMAN,tr|A0A1W2PPC3|A0A1W2PPC3_HUMAN" 14 1954.0173 0.89 118755 15594 4 1954.019713 489.5116 GPI transamidase component PIG-T OS=Homo sapiens OX=9606 GN=PIGT PE=1 SV=1 6.76 2735.6 - 139109 - - - 1.2201 - 2.264 0.437 - 94.3 1 2 0 0.0024 17 0 0 0 3.79E+06 4.25E+06 - - - 3.3127 1 221125_WJC_METTL3_EV_vs_WT_F08.15599.15599.4 1.33E-08 30/126 R.RQPPVSPLTLSPGPEAHQGFSR.Q sp|Q6UUV7|CRTC3_HUMAN 1 2357.224 2.72 118758 15599 4 2357.227659 590.3133 CREB-regulated transcription coactivator 3 OS=Homo sapiens OX=9606 GN=CRTC3 PE=1 SV=2 9.61 2736.3 - 896725 - - - 1.5408 - 5.18 0.568 - 672.3 1 2 0 0.0036 22 0 0 0 1.92E+07 7.05E+06 - - - 4.7071 1 221125_WJC_METTL3_EV_vs_WT_F08.15601.15601.4 3.66E-09 17/138 R.RIPVLSPKPAVAPPAPPSSSQLC[160.03]R.Y "sp|Q6PJT7|ZC3HE_HUMAN,tr|G3V256|G3V256_HUMAN,tr|G3V411|G3V411_HUMAN" 3 2524.3948 1.63 118760 15601 4 2524.395811 632.106 Zinc finger CCCH domain-containing protein 14 OS=Homo sapiens OX=9606 GN=ZC3H14 PE=1 SV=1 10.86 2736.5 - 422608 - - - 0.4013 - 3.062 0.578 - 127.3 1 2 0 0.001 24 0 0 0 1.24E+07 7.61E+06 - - - 4.6158 0.9999 221125_WJC_METTL3_EV_vs_WT_F08.15604.15604.4 3.29E-05 13/90 R.HSIAQLDPEALGNIKK.L sp|Q53HL2|BOREA_HUMAN 1 1732.9472 1.93 118763 15604 4 1732.95016 434.2441 Borealin OS=Homo sapiens OX=9606 GN=CDCA8 PE=1 SV=2 6.75 2736.9 - 240996 - - - 1.7173 - 2.752 0.49 - 187.5 1 2 0 0.003 16 0 0 0 9.07E+06 4.70E+06 - - - 3.8467 0.9999 221125_WJC_METTL3_EV_vs_WT_F08.15605.15605.4 2.48E-05 Dec-90 R.HSIAQLDPEALGNIK[136.11]K[136.11].L sp|Q53HL2|BOREA_HUMAN 1 1748.9756 1.93 118764 15605 4 1748.974739 438.2512 Borealin OS=Homo sapiens OX=9606 GN=CDCA8 PE=1 SV=2 6.75 2737 - 185104 - - - -0.4831 - 2.578 0.469 - 140.3 1 2 0 -0.0008 16 0 0 0 9.07E+06 4.70E+06 - - - 3.6415 0.9995 221125_WJC_METTL3_EV_vs_WT_F08.15609.15609.4 6.13E-06 16/102 K.QFTPC[160.03]QLLADHANSPNKK.F "sp|P40939|ECHA_HUMAN,tr|H0YFD6|H0YFD6_HUMAN,tr|A0A2R8Y4F5|A0A2R8Y4F5_HUMAN" 3 2068.016 0.61 118766 15609 4 2068.023393 518.0113 "Trifunctional enzyme subunit alpha, mitochondrial OS=Homo sapiens OX=9606 GN=HADHA PE=1 SV=2" 8.21 2737.5 - 978413 - - - 3.5706 - 3.04 0.415 - 268.2 1 2 0 0.0074 18 0 0 0 1.98E+07 3.27E+07 - - - 3.217 1 221125_WJC_METTL3_EV_vs_WT_F08.15610.15610.3 1.32E-06 16/104 K.AGEGLGTSSGDAISGTDHNSLDSSLTR.E "sp|Q9ULL5|PRR12_HUMAN,tr|A0A3Q5ADB5|A0A3Q5ADB5_HUMAN" 2 2604.1899 1.52 118767 15610 3 2604.190379 869.0706 Proline-rich protein 12 OS=Homo sapiens OX=9606 GN=PRR12 PE=1 SV=3 4.22 2737.7 - 340014 - - - 0.1663 - 3.73 0.504 - 238.7 1 2 0 0.0004 27 0 0 0 1.80E+07 1.19E+07 - - - 7.1876 1 221125_WJC_METTL3_EV_vs_WT_F08.15611.15611.3 1.93E-09 25/96 K.TPVVQNAASIVQPSPAHVGQQGLSK[136.11].L "sp|Q8WXI9|P66B_HUMAN,tr|A0A0U1RRM1|A0A0U1RRM1_HUMAN" 2 2520.354 1.97 118768 15611 3 2520.35359 841.1253 Transcriptional repressor p66-beta OS=Homo sapiens OX=9606 GN=GATAD2B PE=1 SV=1 8.44 2737.8 - 1.03E+06 - - - -0.1567 - 4.621 0.565 - 545 1 2 0 -0.0004 25 0 0 0 7.24E+08 3.68E+08 - - - 8.3605 1 221125_WJC_METTL3_EV_vs_WT_F08.15612.15612.3 2.09E-12 18/80 K.HGDEIITSTTSNYETQTFSSK.T sp|Q6P2Q9|PRP8_HUMAN 1 2345.0659 1.82 118769 15612 3 2345.077046 782.6959 Pre-mRNA-processing-splicing factor 8 OS=Homo sapiens OX=9606 GN=PRPF8 PE=1 SV=2 4.65 2737.9 - 301616 - - - 4.7466 - 3.667 0.711 - 364.4 1 2 0 0.0111 21 0 0 0 4.88E+06 2.69E+06 - - - 9.5791 0.9998 221125_WJC_METTL3_EV_vs_WT_F08.15617.15617.3 0.00118 Oct-44 K.K[136.11]IHPQTIIAGWR[166.11].E "sp|P78371|TCPB_HUMAN,tr|F8VQ14|F8VQ14_HUMAN,tr|F5GWF6|F5GWF6_HUMAN" 3 1436.8371 0.34 118772 15617 3 1436.836902 479.953 T-complex protein 1 subunit beta OS=Homo sapiens OX=9606 GN=CCT2 PE=1 SV=4 11 2738.6 - 285146 - - - -0.1538 - 2.484 0.327 - 154.9 1 2 0 -0.0002 12 0 0 0 2.49E+06 7.25E+06 - - - 4.7077 1 221125_WJC_METTL3_EV_vs_WT_F08.15619.15619.3 1.29E-06 23/104 K.AGEGLGTSSGDAISGTDHNSLDSSLTR[166.11].E "sp|Q9ULL5|PRR12_HUMAN,tr|A0A3Q5ADB5|A0A3Q5ADB5_HUMAN" 2 2614.1982 1.52 118774 15619 3 2614.196737 872.4067 Proline-rich protein 12 OS=Homo sapiens OX=9606 GN=PRR12 PE=1 SV=3 4.22 2738.9 - 482405 - - - -0.5658 - 3.976 0.624 - 608.4 1 2 0 -0.0015 27 0 0 0 1.80E+07 1.19E+07 - - - 8.6721 0.9998 221125_WJC_METTL3_EV_vs_WT_F08.15620.15620.3 2.89E-05 16/72 R.RGHVTQDAPIPGSPLYTIK.A sp|Q15029|U5S1_HUMAN 1 2049.1007 22.75 118775 15620 3 2049.096869 684.0409 116 kDa U5 small nuclear ribonucleoprotein component OS=Homo sapiens OX=9606 GN=EFTUD2 PE=1 SV=1 8.6 2739 - 377055 - - - -1.8813 - 2.664 0.38 - 297.2 1 2 0 -0.0039 19 0 0 0 3.42E+06 1.50E+05 - - - 5.1828 1 221125_WJC_METTL3_EV_vs_WT_F08.15621.15621.3 5.74E-10 16/112 R.VVDESFVDTSPTGPSSADATTSSEELPKK.E sp|Q9Y535|RPC8_HUMAN 1 2980.4037 1.04 118776 15621 3 2980.404246 994.4752 DNA-directed RNA polymerase III subunit RPC8 OS=Homo sapiens OX=9606 GN=POLR3H PE=1 SV=1 4.02 2739.1 - 311973 - - - 0.1876 - 3.588 0.654 - 181 1 2 0 0.0006 29 0 0 0 7.37E+06 7.06E+06 - - - 8.7706 0.9942 221125_WJC_METTL3_EV_vs_WT_F08.15624.15624.3 1.53E-09 19/72 Q.NSGDVNVEINVAPGKDLTK.T "sp|P35527|K1C9_HUMAN,tr|K7EQQ3|K7EQQ3_HUMAN" 2 1969.0116 999 118777 15624 3 1969.013951 657.3445 "Keratin, type I cytoskeletal 9 OS=Homo sapiens OX=9606 GN=KRT9 PE=1 SV=3" 4.56 2739.5 - 784112 - - - 1.1767 - 3.828 0.58 - 308.5 1 1 1 0.0023 19 0 0 0 1.34E+07 0.00E+00 - - - 8.3037 1 221125_WJC_METTL3_EV_vs_WT_F08.15625.15625.4 5.99E-09 25/144 K.TPVVQNAASIVQPSPAHVGQQGLSK.L "sp|Q8WXI9|P66B_HUMAN,tr|A0A0U1RRM1|A0A0U1RRM1_HUMAN" 2 2512.3398 2.07 118778 15625 4 2512.345435 629.0922 Transcriptional repressor p66-beta OS=Homo sapiens OX=9606 GN=GATAD2B PE=1 SV=1 8.44 2739.6 - 864045 - - - 2.2489 - 4.665 0.554 - 391.4 1 2 0 0.0056 25 0 0 0 8.19E+07 3.97E+07 - - - 4.5364 1 221125_WJC_METTL3_EV_vs_WT_F08.15627.15627.3 1.01E-08 21/80 K.HIQSNLDFSPVNSASSEENVK[136.11].Y "sp|O14757|CHK1_HUMAN,tr|E7EPP6|E7EPP6_HUMAN" 2 2309.1015 0.67 118780 15627 3 2310.098154 770.7078 Serine\threonine-protein kinase Chk1 OS=Homo sapiens OX=9606 GN=CHEK1 PE=1 SV=2 4.65 2739.9 - 763470 - - - 431.6116 - 4.314 0.612 - 569.1 1 2 0 0.9966 21 0 0 0 6.11E+06 9.10E+06 - - - 8.5919 1 221125_WJC_METTL3_EV_vs_WT_F08.15634.15634.3 1.03E-12 19/112 R.VVDESFVDTSPTGPSSADATTSSEELPK[136.11]K[136.11].E sp|Q9Y535|RPC8_HUMAN 1 2996.4321 1.04 118785 15634 3 2996.431746 999.818 DNA-directed RNA polymerase III subunit RPC8 OS=Homo sapiens OX=9606 GN=POLR3H PE=1 SV=1 4.02 2740.8 - 455722 - - - -0.1138 - 3.892 0.676 - 249.9 1 2 0 -0.0003 29 0 0 0 7.37E+06 7.06E+06 - - - 9.203 1 221125_WJC_METTL3_EV_vs_WT_F08.15640.15640.3 2.82E-12 32/100 K.EGIC[160.03]ALGGTSELSSEGTQHSYSEEEK[136.11].Y "sp|P13797|PLST_HUMAN,tr|A0A0A0MSQ0|A0A0A0MSQ0_HUMAN" 2 2792.2174 0.82 118789 15640 3 2792.208997 931.7464 Plastin-3 OS=Homo sapiens OX=9606 GN=PLS3 PE=1 SV=4 4.2 2741.6 - 663913 - - - -3.0141 - 5.156 0.716 - 1394.5 1 2 0 -0.0084 26 0 0 0 5.84E+06 7.16E+06 - - - 10.2938 1 221125_WJC_METTL3_EV_vs_WT_F08.15641.15641.4 4.24E-08 19/138 R.R[166.11]IPVLSPK[136.11]PAVAPPAPPSSSQLC[160.03]R[166.11].Y "sp|Q6PJT7|ZC3HE_HUMAN,tr|G3V256|G3V256_HUMAN,tr|G3V411|G3V411_HUMAN" 3 2552.4255 1.63 118790 15641 4 2552.425931 639.1137 Zinc finger CCCH domain-containing protein 14 OS=Homo sapiens OX=9606 GN=ZC3H14 PE=1 SV=1 10.86 2741.7 - 463451 - - - 0.154 - 3.14 0.628 - 168.7 1 2 0 0.0004 24 0 0 0 1.24E+07 7.61E+06 - - - 5.0593 1 221125_WJC_METTL3_EV_vs_WT_F08.15645.15645.3 3.35E-06 Dec-72 R.HPHDIIDDINSGAVEC[160.03]PAS.- sp|P30050|RL12_HUMAN 1 2045.9113 - 118794 15645 3 2045.913138 682.9777 60S ribosomal protein L12 OS=Homo sapiens OX=9606 GN=RPL12 PE=1 SV=1 4.21 2742.3 - 193109 - - - 0.9135 - 2.609 0.521 - 127.3 1 2 0 0.0019 19 0 0 0 - - - - - 6.7041 0.9999 221125_WJC_METTL3_EV_vs_WT_F08.15647.15647.3 7.37E-05 18/60 R.ETNLDSLPLVDTHSKR.T sp|P08670|VIME_HUMAN 1 1823.9377 1.86 118795 15647 3 1823.94358 608.9865 Vimentin OS=Homo sapiens OX=9606 GN=VIM PE=1 SV=4 5.38 2742.5 - 869865 - - - 3.2013 - 2.994 0.484 - 439.4 1 2 0 0.0058 16 0 0 0 8.29E+08 4.47E+08 - - - 6.7483 0.9235 221125_WJC_METTL3_EV_vs_WT_F08.15648.15648.4 5.91E-05 17/102 F.NDTFVHVTDLSGK[136.11]ETIC[160.03]R[166.11].V "sp|P62263|RS14_HUMAN,tr|A0A2R8Y811|A0A2R8Y811_HUMAN,tr|E5RH77|E5RH77_HUMAN" 3 2109.028 1.45 118796 15648 4 2109.031046 528.2643 40S ribosomal protein S14 OS=Homo sapiens OX=9606 GN=RPS14 PE=1 SV=3 5.38 2742.6 - 242765 - - - 1.4571 - 3.231 0.382 - 251.8 1 1 1 0.0031 18 0 0 0 1.16E+07 8.00E+06 - - - 2.9518 1 221125_WJC_METTL3_EV_vs_WT_F08.15649.15649.4 7.22E-09 28/144 K.TPVVQNAASIVQPSPAHVGQQGLSK[136.11].L "sp|Q8WXI9|P66B_HUMAN,tr|A0A0U1RRM1|A0A0U1RRM1_HUMAN" 2 2520.354 2.07 118797 15649 4 2520.353176 631.0958 Transcriptional repressor p66-beta OS=Homo sapiens OX=9606 GN=GATAD2B PE=1 SV=1 8.44 2742.7 - 1.58E+06 - - - -0.321 - 4.662 0.581 - 574.7 1 2 0 -0.0008 25 0 0 0 8.19E+07 3.96E+07 - - - 4.7725 1 221125_WJC_METTL3_EV_vs_WT_F08.15650.15650.3 1.54E-07 22/84 K.VSANK[136.11]GEIGDATPFNDAVNVQK[136.11].L "sp|P30876|RPB2_HUMAN,tr|C9J4M6|C9J4M6_HUMAN,tr|C9J2Y9|C9J2Y9_HUMAN" 3 2289.1572 1.18 118798 15650 3 2289.159089 764.0597 DNA-directed RNA polymerase II subunit RPB2 OS=Homo sapiens OX=9606 GN=POLR2B PE=1 SV=1 4.56 2742.9 - 1.34E+06 - - - 0.8296 - 3.678 0.609 - 573.6 1 2 1 0.0019 22 0 0 0 3.09E+07 2.62E+07 - - - 8.4169 1 221125_WJC_METTL3_EV_vs_WT_F08.15651.15651.4 1.18E-07 20/132 R.RIPVLSPKPVAPPAPPSSSQLC[160.03]R.Y tr|H0YJA2|H0YJA2_HUMAN 1 2453.3577 2.76 118799 15651 4 2453.35948 614.3467 Zinc finger CCCH domain-containing protein 14 (Fragment) OS=Homo sapiens OX=9606 GN=ZC3H14 PE=1 SV=1 10.86 2743 - 615417 - - - 0.7321 - 3.409 0.526 - 210.8 1 2 0 0.0018 23 0 0 0 7.82E+06 2.84E+06 - - - 4.2012 1 221125_WJC_METTL3_EV_vs_WT_F08.15653.15653.3 1.65E-07 19/80 K.HIQSNLDFSPVNSASSEENVK.Y "sp|O14757|CHK1_HUMAN,tr|E7EPP6|E7EPP6_HUMAN" 2 2301.0873 0.67 118801 15653 3 2301.090683 768.0364 Serine\threonine-protein kinase Chk1 OS=Homo sapiens OX=9606 GN=CHEK1 PE=1 SV=2 4.65 2743.2 - 565502 - - - 1.4619 - 3.819 0.487 - 511.5 1 2 0 0.0034 21 0 0 0 6.11E+06 9.10E+06 - - - 7.1812 0.9999 221125_WJC_METTL3_EV_vs_WT_F08.15654.15654.4 5.07E-07 24/102 K.DHVYLQLHHLPPEQLATR[166.11].L "sp|P31040|SDHA_HUMAN,tr|A0A087X1I3|A0A087X1I3_HUMAN,tr|D6RFM5|D6RFM5_HUMAN" 3 2176.1417 0.51 118802 15654 4 2176.147705 545.0427 "Succinate dehydrogenase [ubiquinone] flavoprotein subunit, mitochondrial OS=Homo sapiens OX=9606 GN=SDHA PE=1 SV=2" 6.26 2743.4 - 404707 - - - 2.7636 - 3.985 0.543 - 619.4 1 2 0 0.006 18 0 0 0 6.34E+06 1.23E+07 - - - 4.4242 1 221125_WJC_METTL3_EV_vs_WT_F08.15656.15656.4 1.98E-07 17/102 K.DHVYLQLHHLPPEQLATR.L "sp|P31040|SDHA_HUMAN,tr|A0A087X1I3|A0A087X1I3_HUMAN,tr|D6RFM5|D6RFM5_HUMAN" 3 2166.1334 0.47 118804 15656 4 2166.136694 542.5406 "Succinate dehydrogenase [ubiquinone] flavoprotein subunit, mitochondrial OS=Homo sapiens OX=9606 GN=SDHA PE=1 SV=2" 6.26 2743.6 - 273599 - - - 1.511 - 3.266 0.521 - 315.9 1 2 0 0.0033 18 0 0 0 7.69E+06 1.62E+07 - - - 4.1653 1 221125_WJC_METTL3_EV_vs_WT_F08.15660.15660.3 1.82E-10 21/84 K.VSANKGEIGDATPFNDAVNVQK.L "sp|P30876|RPB2_HUMAN,tr|C9J4M6|C9J4M6_HUMAN,tr|C9J2Y9|C9J2Y9_HUMAN" 3 2273.1288 1.18 118806 15660 3 2273.129877 758.7169 DNA-directed RNA polymerase II subunit RPB2 OS=Homo sapiens OX=9606 GN=POLR2B PE=1 SV=1 4.56 2744.2 - 2.38E+06 - - - 0.4782 - 4.35 0.636 - 511.9 1 2 1 0.0011 22 0 0 0 3.09E+07 2.62E+07 - - - 9.116 0.9934 221125_WJC_METTL3_EV_vs_WT_F08.15662.15662.3 3.62E-05 20/84 A.FASSLVSGLNSSASEPAK[136.11]EPAK[136.11].K "sp|Q86U44|MTA70_HUMAN,tr|F5H6D8|F5H6D8_HUMAN,tr|H0YFV6|H0YFV6_HUMAN,tr|B4DTN4|B4DTN4_HUMAN" 4 2192.1296 0.001 118808 15662 3 2192.132154 731.7171 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 6.14 2744.4 - 623512 - - - 1.1751 - 3.693 0.572 - 389.5 1 1 1 0.0026 22 0 0 0 0.00E+00 2.77E+07 - - - 8.0139 0.9999 221125_WJC_METTL3_EV_vs_WT_F08.15663.15663.4 2.23E-05 15/84 R.FDVHDVTLHADAIHR[166.11].G sp|P13639|EF2_HUMAN 1 1754.8728 0.67 118809 15663 4 1754.869713 439.7255 Elongation factor 2 OS=Homo sapiens OX=9606 GN=EEF2 PE=1 SV=4 5.71 2744.6 - 587348 - - - -1.7517 - 2.488 0.446 - 237.2 1 2 0 -0.0031 15 0 0 0 5.84E+06 8.75E+06 - - - 3.4333 1 221125_WJC_METTL3_EV_vs_WT_F08.15664.15664.3 5.53E-08 Nov-48 K.HQEYLNSILQHAK[136.11].D "sp|P51531|SMCA2_HUMAN,sp|P51532|SMCA4_HUMAN,tr|A0A2R8Y7S2|A0A2R8Y7S2_HUMAN,tr|A0A2R8YGG3|A0A2R8YGG3_HUMAN,tr|A0A0U1RQZ9|A0A0U1RQZ9_HUMAN,tr|Q9HBD4|Q9HBD4_HUMAN,tr|A0A2R8Y440|A0A2R8Y440_HUMAN,tr|F6VDE0|F6VDE0_HUMAN,tr|A0A2R8YG32|A0A2R8YG32_HUMAN,tr|A0A2R8YGP5|A0A2R8YGP5_HUMAN,tr|A0A2R8Y4P4|A0A2R8Y4P4_HUMAN,tr|A0A2R8Y4C5|A0A2R8Y4C5_HUMAN" 12 1587.8249 0.96 118810 15664 3 1587.824818 530.2822 Probable global transcription activator SNF2L2 OS=Homo sapiens OX=9606 GN=SMARCA2 PE=1 SV=2 6.92 2744.7 - 469940 - - - -0.0453 - 2.679 0.583 - 179.3 1 2 0 -0.0001 13 0 0 0 1.61E+07 1.68E+07 - - - 7.7117 1 221125_WJC_METTL3_EV_vs_WT_F08.15665.15665.3 1.15E-07 15/68 R.SSSLIQLTSQNSSPNQQR[166.11].T "sp|O95639|CPSF4_HUMAN,tr|H7C419|H7C419_HUMAN" 2 1983.9849 1.55 118811 15665 3 1983.984182 662.3356 Cleavage and polyadenylation specificity factor subunit 4 OS=Homo sapiens OX=9606 GN=CPSF4 PE=1 SV=1 9.47 2744.8 - 400229 - - - -0.37 - 3.087 0.526 - 205.3 1 2 0 -0.0007 18 0 0 0 1.23E+07 7.92E+06 - - - 7.211 0.9999 221125_WJC_METTL3_EV_vs_WT_F08.15666.15666.4 0.000162 Dec-84 R.FDVHDVTLHADAIHR.G sp|P13639|EF2_HUMAN 1 1744.8645 0.67 118812 15666 4 1744.866012 437.2234 Elongation factor 2 OS=Homo sapiens OX=9606 GN=EEF2 PE=1 SV=4 5.71 2744.9 - 349278 - - - 0.8568 - 2.437 0.416 - 163.2 1 2 0 0.0015 15 0 0 0 5.62E+06 8.40E+06 - - - 3.1652 0.9999 221125_WJC_METTL3_EV_vs_WT_F08.15670.15670.4 1.21E-07 16/108 R.VEEK[136.11]EPEVTISSIR[166.11]PISER[166.11].A "sp|Q8N6H7|ARFG2_HUMAN,tr|E9PMU9|E9PMU9_HUMAN,tr|E9PQP3|E9PQP3_HUMAN,tr|H0YDN9|H0YDN9_HUMAN,tr|G5E9L0|G5E9L0_HUMAN,tr|A0A0D9SF70|A0A0D9SF70_HUMAN" 6 2225.1898 0.9 118814 15670 4 2225.187698 557.3047 ADP-ribosylation factor GTPase-activating protein 2 OS=Homo sapiens OX=9606 GN=ARFGAP2 PE=1 SV=1 4.65 2745.5 - 1.39E+06 - - - -0.9298 - 2.575 0.542 - 205.9 1 2 1 -0.0021 19 0 0 0 5.00E+07 5.58E+07 - - - 4.263 1 221125_WJC_METTL3_EV_vs_WT_F08.15671.15671.3 4.69E-10 17/92 K.SSVQEEC[160.03]VSTISSSKDEDPLAATR.E "sp|Q7L0Y3|TM10C_HUMAN,tr|C9JVB6|C9JVB6_HUMAN" 2 2595.197 1.02 118815 15671 3 2595.193615 866.0729 tRNA methyltransferase 10 homolog C OS=Homo sapiens OX=9606 GN=TRMT10C PE=1 SV=2 4.18 2745.6 - 590485 - - - -1.3063 - 3.252 0.666 - 209.9 1 2 1 -0.0034 24 0 0 0 2.04E+07 2.00E+07 - - - 8.7033 1 221125_WJC_METTL3_EV_vs_WT_F08.15673.15673.3 0.00382 17/52 K.AQIHDLVLVGGSTR[166.11].L "sp|P0DMV8|HS71A_HUMAN,sp|P0DMV9|HS71B_HUMAN,tr|V9GZ37|V9GZ37_HUMAN,tr|A0A0G2JIW1|A0A0G2JIW1_HUMAN" 4 1474.8131 0.3 118817 15673 3 1474.812049 492.6117 Heat shock 70 kDa protein 1A OS=Homo sapiens OX=9606 GN=HSPA1A PE=1 SV=1 6.79 2745.8 - 774282 - - - -0.7438 - 3.07 0.452 - 353.2 1 2 0 -0.0011 14 0 0 0 1.24E+07 4.07E+07 - - - 6.5599 1 221125_WJC_METTL3_EV_vs_WT_F08.15675.15675.3 3.33E-11 21/100 K.EGIC[160.03]ALGGTSELSSEGTQHSYSEEEK.Y "sp|P13797|PLST_HUMAN,tr|A0A0A0MSQ0|A0A0A0MSQ0_HUMAN" 2 2784.2032 0.82 118819 15675 3 2784.204694 929.075 Plastin-3 OS=Homo sapiens OX=9606 GN=PLS3 PE=1 SV=4 4.2 2746.1 - 416406 - - - 0.5319 - 4.233 0.705 - 439.6 1 2 0 0.0015 26 0 0 0 5.84E+06 7.16E+06 - - - 9.7193 0.9997 221125_WJC_METTL3_EV_vs_WT_F08.15676.15676.4 0.000114 11/120 K.NPPDDTGPVHVPLGHIVANEK.W "sp|Q9BTP7|FAP24_HUMAN,tr|X6R368|X6R368_HUMAN" 2 2205.1178 1.9 118820 15676 4 2205.122939 552.2867 Fanconi anemia core complex-associated protein 24 OS=Homo sapiens OX=9606 GN=FAAP24 PE=1 SV=2 5.21 2746.2 - 276917 - - - 2.3164 - 2.218 0.404 - 84.3 1 2 0 0.0051 21 0 0 0 5.03E+06 2.65E+06 - - - 3.0044 0.9922 221125_WJC_METTL3_EV_vs_WT_F08.15677.15677.3 0.139 Aug-48 R.EQDLPLAEAVRPK.T sp|Q96A49|SYAP1_HUMAN 1 1464.7936 3.86 118821 15677 3 1464.796026 489.2718 Synapse-associated protein 1 OS=Homo sapiens OX=9606 GN=SYAP1 PE=1 SV=1 4.68 2746.4 - 272548 - - - 1.6269 - 1.38 0.252 - 107.4 1 2 0 0.0024 13 0 0 0 1.07E+07 2.78E+06 - - - 2.2222 0.9999 221125_WJC_METTL3_EV_vs_WT_F08.15678.15678.3 9.38E-07 17/48 K.DR[166.11]LLASTLVHSVK[136.11].K "sp|Q9NYF8|BCLF1_HUMAN,tr|E9PKI6|E9PKI6_HUMAN,tr|A0A1W2PQ43|A0A1W2PQ43_HUMAN,tr|E9PK91|E9PK91_HUMAN,tr|E9PJA7|E9PJA7_HUMAN,tr|E9PK09|E9PK09_HUMAN,tr|E9PQN2|E9PQN2_HUMAN" 7 1455.8528 2.82 118822 15678 3 1455.854003 486.2916 Bcl-2-associated transcription factor 1 OS=Homo sapiens OX=9606 GN=BCLAF1 PE=1 SV=2 8.75 2746.5 - 253939 - - - 0.8037 - 3.31 0.473 - 530.4 1 2 1 0.0012 13 0 0 0 1.16E+07 4.13E+06 - - - 7.0584 0.9996 221125_WJC_METTL3_EV_vs_WT_F08.15679.15679.4 0.000551 Oct-90 R.ETNLDSLPLVDTHSK[136.11]R[166.11].T sp|P08670|VIME_HUMAN 1 1841.9602 1.81 118823 15679 4 1841.956404 461.4973 Vimentin OS=Homo sapiens OX=9606 GN=VIM PE=1 SV=4 5.38 2746.6 - 184374 - - - -2.0668 - 1.881 0.377 - 57.4 1 2 0 -0.0038 16 0 0 0 1.38E+09 7.62E+08 - - - 2.7289 1 221125_WJC_METTL3_EV_vs_WT_F08.15682.15682.3 2.84E-06 18/68 R.SSSLIQLTSQNSSPNQQR.T "sp|O95639|CPSF4_HUMAN,tr|H7C419|H7C419_HUMAN" 2 1973.9766 1.4 118824 15682 3 1973.977014 658.9995 Cleavage and polyadenylation specificity factor subunit 4 OS=Homo sapiens OX=9606 GN=CPSF4 PE=1 SV=1 9.47 2747 - 844044 - - - 0.1864 - 3.453 0.518 - 390.5 1 2 0 0.0004 18 0 0 0 1.27E+07 9.04E+06 - - - 7.4009 1 221125_WJC_METTL3_EV_vs_WT_F08.15688.15688.3 1.27E-07 18/48 K.HQEYLNSILQHAK.D "sp|P51531|SMCA2_HUMAN,sp|P51532|SMCA4_HUMAN,tr|A0A2R8Y7S2|A0A2R8Y7S2_HUMAN,tr|A0A2R8YGG3|A0A2R8YGG3_HUMAN,tr|A0A0U1RQZ9|A0A0U1RQZ9_HUMAN,tr|Q9HBD4|Q9HBD4_HUMAN,tr|A0A2R8Y440|A0A2R8Y440_HUMAN,tr|F6VDE0|F6VDE0_HUMAN,tr|A0A2R8YG32|A0A2R8YG32_HUMAN,tr|A0A2R8YGP5|A0A2R8YGP5_HUMAN,tr|A0A2R8Y4P4|A0A2R8Y4P4_HUMAN,tr|A0A2R8Y4C5|A0A2R8Y4C5_HUMAN" 12 1579.8107 0.96 118828 15688 3 1579.811614 527.6108 Probable global transcription activator SNF2L2 OS=Homo sapiens OX=9606 GN=SMARCA2 PE=1 SV=2 6.92 2747.8 - 766285 - - - 0.5849 - 3.037 0.502 - 470.2 1 2 0 0.0009 13 0 0 0 1.61E+07 1.68E+07 - - - 7.1484 0.9999 221125_WJC_METTL3_EV_vs_WT_F08.15690.15690.3 0.00779 Sep-56 K.KVPQVSTPTLVEVSR.N "sp|P02768|ALBU_HUMAN,tr|A0A087WWT3|A0A087WWT3_HUMAN,tr|B7WNR0|B7WNR0_HUMAN,tr|H0YA55|H0YA55_HUMAN,tr|A0A0C4DGB6|A0A0C4DGB6_HUMAN,tr|D6RHD5|D6RHD5_HUMAN,tr|C9JKR2|C9JKR2_HUMAN" 7 1638.9305 999 118830 15690 3 1638.931819 547.3174 Albumin OS=Homo sapiens OX=9606 GN=ALB PE=1 SV=2 8.75 2748.1 - 279764 - - - 0.8225 - 2.266 0.418 - 110.3 1 2 0 0.0013 15 0 0 0 3.44E+06 0.00E+00 - - - 5.3344 1 221125_WJC_METTL3_EV_vs_WT_F08.15691.15691.4 3.65E-07 13/78 R.R[166.11]LPAFTLSHLESHR[166.11].D "sp|Q969V3|NCLN_HUMAN,tr|K7EMW4|K7EMW4_HUMAN,tr|K7ELZ9|K7ELZ9_HUMAN,tr|K7ENM2|K7ENM2_HUMAN,tr|K7EQ66|K7EQ66_HUMAN,tr|A0A0C4DGP7|A0A0C4DGP7_HUMAN" 6 1682.912 2.1 118831 15691 4 1682.911238 421.7353 Nicalin OS=Homo sapiens OX=9606 GN=NCLN PE=1 SV=2 9.61 2748.2 - 274006 - - - -0.4308 - 2.69 0.473 - 108.9 1 2 0 -0.0007 14 0 0 0 9.12E+06 4.35E+06 - - - 3.7029 1 221125_WJC_METTL3_EV_vs_WT_F08.15692.15692.4 1.46E-08 15/78 R.RLPAFTLSHLESHR.D "sp|Q969V3|NCLN_HUMAN,tr|K7EMW4|K7EMW4_HUMAN,tr|K7ELZ9|K7ELZ9_HUMAN,tr|K7ENM2|K7ENM2_HUMAN,tr|K7EQ66|K7EQ66_HUMAN,tr|A0A0C4DGP7|A0A0C4DGP7_HUMAN" 6 1662.8954 1.78 118832 15692 4 1662.897882 416.7311 Nicalin OS=Homo sapiens OX=9606 GN=NCLN PE=1 SV=2 9.61 2748.3 - 207158 - - - 1.4787 - 2.833 0.611 - 207.7 1 2 0 0.0025 14 0 0 0 7.74E+06 4.35E+06 - - - 4.9225 0.9992 221125_WJC_METTL3_EV_vs_WT_F08.15694.15694.3 0.0021 Sep-40 R.AVFPSIVGRPR.Q "sp|Q6S8J3|POTEE_HUMAN,sp|P63261|ACTG_HUMAN,sp|P68133|ACTS_HUMAN,sp|P62736|ACTA_HUMAN,sp|Q9BYX7|ACTBM_HUMAN,sp|P68032|ACTC_HUMAN,sp|P60709|ACTB_HUMAN,sp|P63267|ACTH_HUMAN,sp|A5A3E0|POTEF_HUMAN,sp|P0CG38|POTEI_HUMAN,tr|A0A804GS07|A0A804GS07_HUMAN,tr|I3L3I0|I3L3I0_HUMAN,tr|G5E9R0|G5E9R0_HUMAN,tr|E7EVS6|E7EVS6_HUMAN,tr|B8ZZJ2|B8ZZJ2_HUMAN,tr|J3KT65|J3KT65_HUMAN,tr|I3L3R2|I3L3R2_HUMAN,tr|K7EM38|K7EM38_HUMAN,tr|F6QUT6|F6QUT6_HUMAN,tr|C9JTX5|C9JTX5_HUMAN,tr|A0A6Q8PH58|A0A6Q8PH58_HUMAN,tr|F6UVQ4|F6UVQ4_HUMAN,tr|F8WB63|F8WB63_HUMAN,tr|I3L1U9|I3L1U9_HUMAN,tr|A0A2R8Y793|A0A2R8Y793_HUMAN,tr|I3L4N8|I3L4N8_HUMAN,tr|C9JUM1|C9JUM1_HUMAN,tr|F8WCH0|F8WCH0_HUMAN,tr|C9JZR7|C9JZR7_HUMAN,tr|C9JFL5|C9JFL5_HUMAN,tr|A0A2R8YGF8|A0A2R8YGF8_HUMAN,tr|A6NL76|A6NL76_HUMAN" 32 1197.6982 1.57 118834 15694 3 1197.702613 400.24 POTE ankyrin domain family member E OS=Homo sapiens OX=9606 GN=POTEE PE=2 SV=3 12 2748.6 - 140367 - - - 3.6629 - 2.049 0.39 - 110.2 1 2 0 0.0044 11 0 0 0 7.65E+06 4.86E+06 - - - 4.9248 1 221125_WJC_METTL3_EV_vs_WT_F08.15695.15695.2 7.13E-09 15/34 R.SSSLIQLTSQNSSPNQQR.T "sp|O95639|CPSF4_HUMAN,tr|H7C419|H7C419_HUMAN" 2 1973.9766 2.07 118835 15695 2 1973.982146 987.9956 Cleavage and polyadenylation specificity factor subunit 4 OS=Homo sapiens OX=9606 GN=CPSF4 PE=1 SV=1 9.47 2748.7 - 121023 - - - 2.7863 - 3.025 0.635 - 736 1 2 0 0.0055 18 0 0 0 2.28E+06 1.10E+06 - - - 6.4508 0.9994 221125_WJC_METTL3_EV_vs_WT_F08.15696.15696.3 0.00887 6/100 R.LGVPC[160.03]GEPAELGGDASEEDHPQVC[160.03]AK.C "tr|A0A087X1T9|A0A087X1T9_HUMAN,tr|F5H433|F5H433_HUMAN,tr|E7EW59|E7EW59_HUMAN" 3 2721.201 4.31 118836 15696 3 2721.201471 908.0743 Sal-like protein 2 OS=Homo sapiens OX=9606 GN=SALL2 PE=1 SV=1 4.08 2748.8 - 0 - - - 0.1565 - 1.295 0.406 - 18.1 1 2 0 0.0004 26 0 0 0 1.21E+06 2.81E+05 - - - 3.6611 0.9956 221125_WJC_METTL3_EV_vs_WT_F08.15700.15700.3 4.48E-09 17/100 R.GGASQRPLTPNQNQQGQQTDPLVAAA.A "sp|Q14671|PUM1_HUMAN,tr|Q5T1Z8|Q5T1Z8_HUMAN,tr|H0YDK8|H0YDK8_HUMAN,tr|H0YEH2|H0YEH2_HUMAN,tr|Q5T1Z4|Q5T1Z4_HUMAN,tr|H0YED4|H0YED4_HUMAN,tr|E9PR38|E9PR38_HUMAN" 7 2646.311 3.3 118838 15700 3 2646.319081 883.1109 Pumilio homolog 1 OS=Homo sapiens OX=9606 GN=PUM1 PE=1 SV=3 5.84 2749.4 - 549948 - - - 3.0522 - 3.424 0.609 - 180.2 1 1 0 0.0081 26 0 0 0 1.32E+07 3.99E+06 - - - 8.1592 0.9827 221125_WJC_METTL3_EV_vs_WT_F08.15702.15702.3 8.20E-08 17/72 K.PSTASAVPELATDPELEK[136.11]K[136.11].L "sp|Q86U44|MTA70_HUMAN,tr|B4E349|B4E349_HUMAN,tr|F5H6D8|F5H6D8_HUMAN,tr|H0YFV6|H0YFV6_HUMAN,tr|B4DTN4|B4DTN4_HUMAN" 5 1998.0492 0.001 118840 15702 3 1998.050194 667.0237 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 4.41 2749.6 - 407172 - - - 0.4965 - 2.693 0.336 - 242.1 1 1 0 0.001 19 0 0 0 0.00E+00 1.02E+08 - - - 4.7196 0.9995 221125_WJC_METTL3_EV_vs_WT_F08.15706.15706.3 0.0174 Aug-40 R.AVFPSIVGR[166.11]PR[166.11].Q "sp|Q6S8J3|POTEE_HUMAN,sp|P63261|ACTG_HUMAN,sp|P68133|ACTS_HUMAN,sp|P62736|ACTA_HUMAN,sp|Q9BYX7|ACTBM_HUMAN,sp|P68032|ACTC_HUMAN,sp|P60709|ACTB_HUMAN,sp|P63267|ACTH_HUMAN,sp|A5A3E0|POTEF_HUMAN,sp|P0CG38|POTEI_HUMAN,tr|A0A804GS07|A0A804GS07_HUMAN,tr|I3L3I0|I3L3I0_HUMAN,tr|G5E9R0|G5E9R0_HUMAN,tr|E7EVS6|E7EVS6_HUMAN,tr|B8ZZJ2|B8ZZJ2_HUMAN,tr|J3KT65|J3KT65_HUMAN,tr|I3L3R2|I3L3R2_HUMAN,tr|K7EM38|K7EM38_HUMAN,tr|F6QUT6|F6QUT6_HUMAN,tr|C9JTX5|C9JTX5_HUMAN,tr|A0A6Q8PH58|A0A6Q8PH58_HUMAN,tr|F6UVQ4|F6UVQ4_HUMAN,tr|F8WB63|F8WB63_HUMAN,tr|I3L1U9|I3L1U9_HUMAN,tr|A0A2R8Y793|A0A2R8Y793_HUMAN,tr|I3L4N8|I3L4N8_HUMAN,tr|C9JUM1|C9JUM1_HUMAN,tr|F8WCH0|F8WCH0_HUMAN,tr|C9JZR7|C9JZR7_HUMAN,tr|C9JFL5|C9JFL5_HUMAN,tr|A0A2R8YGF8|A0A2R8YGF8_HUMAN,tr|A6NL76|A6NL76_HUMAN" 32 1217.7148 1.56 118844 15706 3 1217.714795 406.9122 POTE ankyrin domain family member E OS=Homo sapiens OX=9606 GN=POTEE PE=2 SV=3 12 2750.1 - 124467 - - - 0.0238 - 1.713 0.343 - 91.3 1 2 0 0 11 0 0 0 7.70E+06 4.92E+06 - - - 3.8932 1 221125_WJC_METTL3_EV_vs_WT_F08.15710.15710.4 6.76E-10 23/108 R.HC[160.03]VTFVLHEEDHTLGNSLR[166.11].Y "sp|P0DPB6|RPAC2_HUMAN,tr|A0A0R4J2F3|A0A0R4J2F3_HUMAN" 2 2273.0887 0.02 118846 15710 4 2273.089891 569.2794 DNA-directed RNA polymerases I and III subunit RPAC2 OS=Homo sapiens OX=9606 GN=POLR1D PE=1 SV=1 5.75 2750.6 - 774524 - - - 0.5372 - 4.042 0.647 - 414.9 1 2 0 0.0012 19 0 0 0 2.25E+06 1.03E+08 - - - 5.3296 1 221125_WJC_METTL3_EV_vs_WT_F08.15711.15711.3 1.03E-07 23/80 R.RVNSASSSNPPAEVDPDTILK.A "sp|Q9BY77|PDIP3_HUMAN,tr|F6VRR5|F6VRR5_HUMAN" 2 2196.1022 1.68 118847 15711 3 2196.094702 733.0414 Polymerase delta-interacting protein 3 OS=Homo sapiens OX=9606 GN=POLDIP3 PE=1 SV=2 4.56 2750.8 - 946988 - - - -3.4324 - 3.797 0.602 - 507.9 1 2 0 -0.0075 21 0 0 0 2.41E+09 1.44E+09 - - - 8.4483 0.9999 221125_WJC_METTL3_EV_vs_WT_F08.15714.15714.4 0.000106 Dec-72 R.AFDHVLHLRPLSR.L "sp|Q9H6R4|NOL6_HUMAN,tr|A0A0A0MRW6|A0A0A0MRW6_HUMAN" 2 1559.8685 0.97 118850 15714 4 1559.869508 390.9744 Nucleolar protein 6 OS=Homo sapiens OX=9606 GN=NOL6 PE=1 SV=2 9.65 2751.2 - 300510 - - - 0.659 - 1.88 0.442 - 116.3 1 2 0 0.001 13 0 0 0 4.42E+06 4.58E+06 - - - 3.3069 1 221125_WJC_METTL3_EV_vs_WT_F08.15721.15721.3 2.67E-11 24/80 R.R[166.11]VNSASSSNPPAEVDPDTILK[136.11].A "sp|Q9BY77|PDIP3_HUMAN,tr|F6VRR5|F6VRR5_HUMAN" 2 2214.1247 1.67 118855 15721 3 2214.126883 739.0488 Polymerase delta-interacting protein 3 OS=Homo sapiens OX=9606 GN=POLDIP3 PE=1 SV=2 4.56 2752.1 - 1.12E+06 - - - 0.9814 - 3.925 0.617 - 499.4 1 2 0 0.0022 21 0 0 0 2.41E+09 1.44E+09 - - - 8.6965 1 221125_WJC_METTL3_EV_vs_WT_F08.15723.15723.4 3.58E-05 14/114 R.LK[136.11]PDEGGEVPVLNVSYK[136.11]PQK[136.11].L "sp|P61221|ABCE1_HUMAN,tr|D6R9I9|D6R9I9_HUMAN" 2 2220.2216 1.1 118857 15723 4 2220.224736 556.0627 ATP-binding cassette sub-family E member 1 OS=Homo sapiens OX=9606 GN=ABCE1 PE=1 SV=1 6.18 2752.3 - 1.13E+06 - - - 1.3972 - 2.929 0.478 - 131.2 1 2 0 0.0031 20 0 0 0 5.89E+07 5.33E+07 - - - 3.7449 0.9929 221125_WJC_METTL3_EV_vs_WT_F08.15724.15724.4 9.25E-05 13/96 K.GYPHLC[160.03]SIC[160.03]DLPVHSNK.E "sp|P43243|MATR3_HUMAN,tr|A8MXP9|A8MXP9_HUMAN,tr|D6R991|D6R991_HUMAN,tr|A0A0R4J2E8|A0A0R4J2E8_HUMAN,tr|H0Y8T4|H0Y8T4_HUMAN,tr|D6REM6|D6REM6_HUMAN" 6 1995.9295 1.29 118858 15724 4 1996.931309 499.9897 Matrin-3 OS=Homo sapiens OX=9606 GN=MATR3 PE=1 SV=2 6.9 2752.4 - 421397 - - - 501.925 - 2.313 0.387 - 87.8 1 2 0 1.0018 17 0 0 0 1.31E+09 1.01E+09 - - - 2.6081 1 221125_WJC_METTL3_EV_vs_WT_F08.15726.15726.3 1.46E-07 14/68 K.YVHYEIDAC[160.03]MDSEAPGSK[136.11].D "sp|Q86U44|MTA70_HUMAN,tr|H0YFV6|H0YFV6_HUMAN" 2 2078.8805 0.001 118860 15726 3 2078.874671 693.9674 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 4.31 2752.7 - 240158 - - - -2.8001 - 3.136 0.629 - 214.6 1 2 0 -0.0058 18 0 0 0 0.00E+00 2.99E+06 - - - 8.3972 0.9997 221125_WJC_METTL3_EV_vs_WT_F08.15730.15730.3 1.52E-06 Nov-72 K.QYYIGDIHPSDLK[136.11]PESGSK[136.11].D "sp|O43169|CYB5B_HUMAN,tr|H3BUX2|H3BUX2_HUMAN" 2 2149.0662 0.96 118864 15730 3 2149.061159 717.3627 Cytochrome b5 type B OS=Homo sapiens OX=9606 GN=CYB5B PE=1 SV=3 5.38 2753.2 - 130893 - - - -2.3685 - 2.302 0.391 - 104 1 2 0 -0.0051 19 0 0 0 1.37E+07 1.43E+07 - - - 4.9463 0.9998 221125_WJC_METTL3_EV_vs_WT_F08.15733.15733.4 1.31E-09 21/114 K.AK[136.11]LDNLDEEWATEHAC[160.03]QVSR[166.11].M sp|Q5SWX8|ODR4_HUMAN 1 2389.1087 1.16 118865 15733 4 2389.110494 598.2845 Protein odr-4 homolog OS=Homo sapiens OX=9606 GN=ODR4 PE=1 SV=1 4.5 2753.6 - 764863 - - - 0.7329 - 4.125 0.463 - 418.3 1 2 1 0.0018 20 0 0 0 1.64E+07 1.41E+07 - - - 3.7292 0.9999 221125_WJC_METTL3_EV_vs_WT_F08.15734.15734.4 3.18E-06 24/108 K.QYYIGDIHPSDLKPESGSK.D "sp|O43169|CYB5B_HUMAN,tr|H3BUX2|H3BUX2_HUMAN" 2 2133.0378 1.22 118866 15734 4 2133.041831 534.2667 Cytochrome b5 type B OS=Homo sapiens OX=9606 GN=CYB5B PE=1 SV=3 5.38 2753.7 - 781815 - - - 1.8668 - 3.35 0.488 - 362.5 1 2 0 0.004 19 0 0 0 4.37E+07 3.60E+07 - - - 3.8814 0.9999 221125_WJC_METTL3_EV_vs_WT_F08.15735.15735.4 0.000295 17/108 K.QYYIGDIHPSDLK[136.11]PESGSK[136.11].D "sp|O43169|CYB5B_HUMAN,tr|H3BUX2|H3BUX2_HUMAN" 2 2149.0662 1.25 118867 15735 4 2149.069358 538.2738 Cytochrome b5 type B OS=Homo sapiens OX=9606 GN=CYB5B PE=1 SV=3 5.38 2753.9 - 726955 - - - 1.4467 - 2.876 0.457 - 159.8 1 2 0 0.0031 19 0 0 0 4.37E+07 3.48E+07 - - - 3.5602 0.9999 221125_WJC_METTL3_EV_vs_WT_F08.15736.15736.4 1.52E-10 19/102 K.FLYQLHETEKEDLIREER.S "sp|O75643|U520_HUMAN,tr|A0A494C1A5|A0A494C1A5_HUMAN" 2 2347.1808 1.53 118868 15736 4 2347.185781 587.8025 U5 small nuclear ribonucleoprotein 200 kDa helicase OS=Homo sapiens OX=9606 GN=SNRNP200 PE=1 SV=2 4.7 2754 - 645395 - - - 2.1115 - 3.391 0.575 - 290.2 1 2 2 0.005 18 0 0 0 1.36E+07 8.87E+06 - - - 4.6477 0.9999 221125_WJC_METTL3_EV_vs_WT_F08.15737.15737.4 4.73E-09 19/144 K.ITEAPASEK[136.11]EIVEVK[136.11]EENIEDATEK[136.11].G "sp|P82970|HMGN5_HUMAN,tr|Q5JSK9|Q5JSK9_HUMAN,tr|Q5JSK6|Q5JSK6_HUMAN,tr|Q5JSL0|Q5JSL0_HUMAN" 4 2824.4292 1.39 118869 15737 4 2824.432915 707.1146 High mobility group nucleosome-binding domain-containing protein 5 OS=Homo sapiens OX=9606 GN=HMGN5 PE=1 SV=1 4.14 2754.1 - 395592 - - - 1.3224 - 3.445 0.542 - 213.4 1 2 2 0.0037 25 0 0 0 3.40E+06 2.45E+06 - - - 4.336 0.9996 221125_WJC_METTL3_EV_vs_WT_F08.15738.15738.4 0.000377 14/72 R.AFDHVLHLR[166.11]PLSR[166.11].L "sp|Q9H6R4|NOL6_HUMAN,tr|A0A0A0MRW6|A0A0A0MRW6_HUMAN" 2 1579.885 0.97 118870 15738 4 1579.887003 395.9785 Nucleolar protein 6 OS=Homo sapiens OX=9606 GN=NOL6 PE=1 SV=2 9.65 2754.3 - 323100 - - - 1.2552 - 2.067 0.345 - 195.3 1 2 0 0.002 13 0 0 0 4.42E+06 4.58E+06 - - - 2.4975 0.9931 221125_WJC_METTL3_EV_vs_WT_F08.15741.15741.4 0.375 14/108 K.RGEPAIYRPLDPKPFPNYR.A "sp|Q9NUL3|STAU2_HUMAN,tr|E7EVJ4|E7EVJ4_HUMAN,tr|E7EVI1|E7EVI1_HUMAN,tr|E7EPX0|E7EPX0_HUMAN,tr|E5RGT3|E5RGT3_HUMAN,tr|E5RFK1|E5RFK1_HUMAN" 6 2285.2069 2.18 118871 15741 4 2285.20904 572.309 Double-stranded RNA-binding protein Staufen homolog 2 OS=Homo sapiens OX=9606 GN=STAU2 PE=1 SV=2 9.69 2754.7 - 413884 - - - 0.9273 - 1.862 0.214 - 91.2 1 2 0 0.0021 19 0 0 0 6.28E+06 2.88E+06 - - - 1.2984 1 221125_WJC_METTL3_EV_vs_WT_F08.15745.15745.3 1.87E-18 27/76 K.AKLDNLDEEWATEHAC[160.03]QVSR.M sp|Q5SWX8|ODR4_HUMAN 1 2371.0863 1.45 118875 15745 3 2371.085364 791.3694 Protein odr-4 homolog OS=Homo sapiens OX=9606 GN=ODR4 PE=1 SV=1 4.5 2755.2 - 543643 - - - -0.3834 - 4.871 0.726 - 1110.2 1 2 1 -0.0009 20 0 0 0 6.19E+06 4.28E+06 - - - 10.4751 0.9998 221125_WJC_METTL3_EV_vs_WT_F08.15749.15749.4 0.00549 10/144 R.SEAEEAITSFNGHKPPGSSEPITVK.F sp|Q15717|ELAV1_HUMAN 1 2611.2766 4 118877 15749 4 2611.279565 653.8264 ELAV-like protein 1 OS=Homo sapiens OX=9606 GN=ELAVL1 PE=1 SV=2 4.9 2755.7 - 215761 - - - 1.1447 - 2.04 0.39 - 47 1 2 0 0.003 25 0 0 0 1.88E+06 4.69E+05 - - - 2.8465 0.9635 221125_WJC_METTL3_EV_vs_WT_F08.15751.15751.3 0.0842 Aug-48 K.GIHPTIISESFQK[136.11].A sp|P50991|TCPD_HUMAN 1 1463.7864 0.7 118879 15751 3 1463.790119 488.9361 T-complex protein 1 subunit delta OS=Homo sapiens OX=9606 GN=CCT4 PE=1 SV=4 6.75 2756 - 399018 - - - 2.555 - 1.482 0.182 - 74.2 1 2 0 0.0037 13 0 0 0 5.54E+06 7.94E+06 - - - 1.6347 1 221125_WJC_METTL3_EV_vs_WT_F08.15758.15758.3 6.13E-05 20/60 K.KQNASLQAAITDAEQR.G sp|Q8N1N4|K2C78_HUMAN 1 1742.8911 999 118884 15758 3 1742.894494 581.971 "Keratin, type II cytoskeletal 78 OS=Homo sapiens OX=9606 GN=KRT78 PE=1 SV=2" 6.07 2756.9 - 1.29E+06 - - - 1.933 - 3.743 0.522 - 683.6 1 2 0 0.0034 16 0 0 0 3.41E+07 0.00E+00 - - - 7.7455 0.9995 221125_WJC_METTL3_EV_vs_WT_F08.15760.15760.3 8.84E-09 17/84 K.EEVKEAYMGNVLQGGEGQAPTR.Q "sp|P24752|THIL_HUMAN,tr|A0A5F9ZHL7|A0A5F9ZHL7_HUMAN,tr|A0A5F9ZHJ7|A0A5F9ZHJ7_HUMAN,tr|A0A5F9ZHH9|A0A5F9ZHH9_HUMAN,tr|A0A5F9ZHL1|A0A5F9ZHL1_HUMAN,tr|E9PRQ6|E9PRQ6_HUMAN,tr|H0YEL7|H0YEL7_HUMAN" 7 2362.1223 1.53 118886 15760 3 2362.131071 788.3814 "Acetyl-CoA acetyltransferase, mitochondrial OS=Homo sapiens OX=9606 GN=ACAT1 PE=1 SV=1" 4.49 2757.2 - 507904 - - - 3.703 - 3.067 0.541 - 213.2 1 2 1 0.0087 22 0 0 0 1.84E+07 1.20E+07 - - - 7.2262 0.9934 221125_WJC_METTL3_EV_vs_WT_F08.15762.15762.4 0.0332 14/84 K.VKELVEFAQDDDRLR.E sp|Q14677|EPN4_HUMAN 1 1831.9428 0.88 118888 15762 4 1831.946062 458.993 Clathrin interactor 1 OS=Homo sapiens OX=9606 GN=CLINT1 PE=1 SV=1 4.44 2757.4 - 373717 - - - 1.7659 - 1.926 0.288 - 161.3 1 2 2 0.0032 15 0 0 0 4.07E+06 4.64E+06 - - - 1.9664 0.9998 221125_WJC_METTL3_EV_vs_WT_F08.15763.15763.4 6.31E-07 16/150 K.ALAEENKNTVDVENGASMAGYADLKR.T "sp|Q96EE4|CC126_HUMAN,tr|C9J0J0|C9J0J0_HUMAN" 2 2765.329 2.47 118889 15763 4 2765.334767 692.3395 Coiled-coil domain-containing protein 126 OS=Homo sapiens OX=9606 GN=CCDC126 PE=2 SV=2 4.51 2757.6 - 358030 - - - 2.0775 - 3.159 0.524 - 129.5 1 2 1 0.0057 26 0 0 0 2.15E+06 8.71E+05 - - - 4.1481 0.993 221125_WJC_METTL3_EV_vs_WT_F08.15764.15764.4 0.253 8/108 R.GLLQDDAHPTLVTYADHSK[136.11].L "sp|Q86U44|MTA70_HUMAN,tr|F5H6D8|F5H6D8_HUMAN,tr|H0YFV6|H0YFV6_HUMAN,tr|B4DTN4|B4DTN4_HUMAN" 4 2088.0367 0.04 118890 15764 4 2088.036251 523.0165 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 5.13 2757.7 - 188347 - - - -0.2308 - 1.978 0.211 - 52.1 1 2 0 -0.0005 19 0 0 0 1.43E+05 3.74E+06 - - - 1.2931 1 221125_WJC_METTL3_EV_vs_WT_F08.15770.15770.3 7.37E-10 19/84 K.EEVK[136.11]EAYMGNVLQGGEGQAPTR[166.11].Q "sp|P24752|THIL_HUMAN,tr|A0A5F9ZHL7|A0A5F9ZHL7_HUMAN,tr|A0A5F9ZHJ7|A0A5F9ZHJ7_HUMAN,tr|A0A5F9ZHH9|A0A5F9ZHH9_HUMAN,tr|A0A5F9ZHL1|A0A5F9ZHL1_HUMAN,tr|E9PRQ6|E9PRQ6_HUMAN,tr|H0YEL7|H0YEL7_HUMAN" 7 2380.1448 1.51 118894 15770 3 2380.14509 794.3889 "Acetyl-CoA acetyltransferase, mitochondrial OS=Homo sapiens OX=9606 GN=ACAT1 PE=1 SV=1" 4.49 2758.5 - 738102 - - - 0.1244 - 3.548 0.603 - 297.7 1 2 1 0.0003 22 0 0 0 1.82E+07 1.20E+07 - - - 8.2652 1 221125_WJC_METTL3_EV_vs_WT_F08.15771.15771.3 9.53E-10 19/72 R.SDNVVEGNC[160.03]ADELLQNSHR.V "sp|O43716|GATC_HUMAN,tr|H0YIV9|H0YIV9_HUMAN,tr|J3KMY1|J3KMY1_HUMAN" 3 2155.9553 2.36 118895 15771 3 2155.960733 719.659 "Glutamyl-tRNA(Gln) amidotransferase subunit C, mitochondrial OS=Homo sapiens OX=9606 GN=GATC PE=1 SV=1" 4.31 2758.6 - 558822 - - - 2.539 - 3.627 0.687 - 493 1 2 0 0.0055 19 0 0 0 1.19E+07 5.04E+06 - - - 9.3632 0.9999 221125_WJC_METTL3_EV_vs_WT_F08.15774.15774.3 1.66E-08 13/84 R.QSQQEAEEEEREEEEEAQIIQR.R sp|Q9NQZ2|SAS10_HUMAN 1 2716.206 1.05 118898 15774 3 2716.2092 906.4093 Something about silencing protein 10 OS=Homo sapiens OX=9606 GN=UTP3 PE=1 SV=1 3.92 2759 - 282693 - - - 1.1818 - 2.872 0.569 - 137.3 1 2 1 0.0032 22 0 0 0 6.25E+06 5.97E+06 - - - 7.3841 0.9809 221125_WJC_METTL3_EV_vs_WT_F08.15775.15775.3 0.16 May-80 K.ITVPGNFQGHSGAQC[160.03]ITC[160.03]SYK.A sp|Q08945|SSRP1_HUMAN 1 2324.0678 1.63 118899 15775 3 2324.066969 775.6965 FACT complex subunit SSRP1 OS=Homo sapiens OX=9606 GN=SSRP1 PE=1 SV=1 8.05 2759.2 - 232628 - - - -0.3515 - 1.353 0.238 - 16.6 12 2 0 -0.0008 21 0 0 0 3.24E+06 1.99E+06 - - - 1.4186 0.9018 221125_WJC_METTL3_EV_vs_WT_F08.15777.15777.3 2.59 Jun-76 K.AK[136.11]LDNLDEEWATEHAC[160.03]QVSR[166.11].M sp|Q5SWX8|ODR4_HUMAN 1 2389.1087 1.45 118901 15777 3 2389.109894 797.3769 Protein odr-4 homolog OS=Homo sapiens OX=9606 GN=ODR4 PE=1 SV=1 4.5 2759.4 - 272974 - - - 0.4818 - 1.419 0.172 - 19.7 1 2 1 0.0012 20 0 0 0 6.19E+06 4.28E+06 - - - 1.3063 0.9916 221125_WJC_METTL3_EV_vs_WT_F08.15778.15778.3 0.0979 Jun-68 K.FLYQLHETEKEDLIREER.S "sp|O75643|U520_HUMAN,tr|A0A494C1A5|A0A494C1A5_HUMAN" 2 2347.1808 3.38 118902 15778 3 2347.183614 783.4009 U5 small nuclear ribonucleoprotein 200 kDa helicase OS=Homo sapiens OX=9606 GN=SNRNP200 PE=1 SV=2 4.7 2759.6 - 154075 - - - 1.1882 - 1.963 0.264 - 39.2 2 2 2 0.0028 18 0 0 0 1.21E+06 3.58E+05 - - - 3.0228 1 221125_WJC_METTL3_EV_vs_WT_F08.15782.15782.3 2.15E-08 23/56 R.STSHK[136.11]PDEIYGMIER[166.11].L sp|Q86U44|MTA70_HUMAN 1 1779.8581 0 118904 15782 3 1779.85902 594.2933 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 5.42 2760.1 - 1.30E+06 - - - 0.5427 - 3.563 0.54 - 651.2 1 2 0 0.001 15 0 0 0 8.26E+04 5.50E+07 - - - 7.8757 1 221125_WJC_METTL3_EV_vs_WT_F08.15783.15783.4 1.32E-06 18/114 R.SFFQDEHVADSENAENRPFR.R "sp|Q5JSZ5|PRC2B_HUMAN,tr|A0A804HKC3|A0A804HKC3_HUMAN" 2 2394.0625 2 118905 15783 4 2394.064663 599.5229 Protein PRRC2B OS=Homo sapiens OX=9606 GN=PRRC2B PE=1 SV=2 4.5 2760.2 - 1.13E+06 - - - 0.9031 - 3.116 0.516 - 128 1 2 0 0.0022 20 0 0 0 2.61E+07 1.30E+07 - - - 4.0966 0.9999 221125_WJC_METTL3_EV_vs_WT_F08.15784.15784.3 1.32E-07 17/60 K.TDEDEKTILNLENSNK.S sp|Q8IX12|CCAR1_HUMAN 1 1861.8905 5.57 118906 15784 3 1861.895353 621.6374 Cell division cycle and apoptosis regulator protein 1 OS=Homo sapiens OX=9606 GN=CCAR1 PE=1 SV=2 4.18 2760.3 - 893904 - - - 2.5979 - 3.153 0.608 - 428.3 1 2 1 0.0048 16 0 0 0 8.21E+07 1.47E+07 - - - 8.2638 0.9932 221125_WJC_METTL3_EV_vs_WT_F08.15787.15787.4 0.0066 Oct-90 K.VILHLK[136.11]EDQTEYLEER[166.11].R "sp|P08238|HS90B_HUMAN,sp|Q58FF6|H90B4_HUMAN,sp|Q58FF7|H90B3_HUMAN,sp|P07900|HS90A_HUMAN,tr|G3V2J8|G3V2J8_HUMAN" 5 2032.0596 0.74 118909 15787 4 2032.062641 509.0222 Heat shock protein HSP 90-beta OS=Homo sapiens OX=9606 GN=HSP90AB1 PE=1 SV=4 4.57 2760.7 - 427860 - - - 1.5009 - 1.788 0.283 - 92.8 1 2 1 0.0031 16 0 0 0 3.94E+06 5.33E+06 - - - 1.8931 1 221125_WJC_METTL3_EV_vs_WT_F08.15789.15789.3 0.000146 Sep-80 K.ITVPGNFQGHSGAQC[160.03]ITC[160.03]SYK[136.11].A sp|Q08945|SSRP1_HUMAN 1 2332.082 1.63 118911 15789 3 2332.081463 778.3679 FACT complex subunit SSRP1 OS=Homo sapiens OX=9606 GN=SSRP1 PE=1 SV=1 8.05 2761 - 275138 - - - -0.2243 - 2.084 0.514 - 48.1 1 2 0 -0.0005 21 0 0 0 3.24E+06 1.99E+06 - - - 6.0309 1 221125_WJC_METTL3_EV_vs_WT_F08.15791.15791.3 2.29E-05 8/120 R.ELGTGEQPLSPTTATSPYGGGHALAGQTSPK[136.11].Q "sp|Q96NU1|SAM11_HUMAN,tr|A0A087WYW1|A0A087WYW1_HUMAN,tr|A0A087WX24|A0A087WX24_HUMAN,tr|A0A087X1J5|A0A087X1J5_HUMAN,tr|A0A087X223|A0A087X223_HUMAN,tr|H7BY14|H7BY14_HUMAN,tr|A0A087WXB3|A0A087WXB3_HUMAN,tr|H7C3J6|H7C3J6_HUMAN,tr|A0A087WYU3|A0A087WYU3_HUMAN,tr|A0A087WU74|A0A087WU74_HUMAN" 10 3017.4822 2.2 118913 15791 3 3017.479733 1006.8347 Sterile alpha motif domain-containing protein 11 OS=Homo sapiens OX=9606 GN=SAMD11 PE=1 SV=3 5.4 2761.2 - 136955 - - - -0.804 - 2.31 0.489 - 32 1 2 0 -0.0024 31 0 0 0 3.27E+06 1.49E+06 - - - 5.9174 1 221125_WJC_METTL3_EV_vs_WT_F08.15796.15796.4 1.36E-07 17/114 R.SFFQDEHVADSENAENR[166.11]PFR[166.11].R "sp|Q5JSZ5|PRC2B_HUMAN,tr|A0A804HKC3|A0A804HKC3_HUMAN" 2 2414.079 2 118916 15796 4 2414.080936 604.527 Protein PRRC2B OS=Homo sapiens OX=9606 GN=PRRC2B PE=1 SV=2 4.5 2761.9 - 1.65E+06 - - - 0.785 - 2.824 0.537 - 116.7 1 2 0 0.0019 20 0 0 0 2.61E+07 1.30E+07 - - - 4.2466 0.9999 221125_WJC_METTL3_EV_vs_WT_F08.15798.15798.3 2.23E-08 16/60 K.ILDSVGIEADDDRLNK.V sp|P05387|RLA2_HUMAN 1 1771.8952 1.42 118918 15798 3 1771.898037 591.639 60S acidic ribosomal protein P2 OS=Homo sapiens OX=9606 GN=RPLP2 PE=1 SV=1 4.04 2762.1 - 839005 - - - 1.5966 - 3.075 0.509 - 276.3 1 2 1 0.0028 16 0 0 0 1.06E+07 7.48E+06 - - - 7.0963 1 221125_WJC_METTL3_EV_vs_WT_F08.15799.15799.3 1.39E-07 20/72 K.QYYIGDIHPSDLKPESGSK.D "sp|O43169|CYB5B_HUMAN,tr|H3BUX2|H3BUX2_HUMAN" 2 2133.0378 0.96 118919 15799 3 2133.041165 712.0199 Cytochrome b5 type B OS=Homo sapiens OX=9606 GN=CYB5B PE=1 SV=3 5.38 2762.3 - 763121 - - - 1.5546 - 3.156 0.568 - 440.8 1 2 0 0.0033 19 0 0 0 1.37E+07 1.43E+07 - - - 7.6953 1 221125_WJC_METTL3_EV_vs_WT_F08.15806.15806.3 0.000148 15/76 R.SFFQDEHVADSENAENRPFR.R "sp|Q5JSZ5|PRC2B_HUMAN,tr|A0A804HKC3|A0A804HKC3_HUMAN" 2 2394.0625 2.41 118924 15806 3 2394.066174 799.0281 Protein PRRC2B OS=Homo sapiens OX=9606 GN=PRRC2B PE=1 SV=2 4.5 2763.3 - 912236 - - - 1.5342 - 2.337 0.542 - 131.5 1 2 0 0.0037 20 0 0 0 7.43E+06 3.09E+06 - - - 6.6411 1 221125_WJC_METTL3_EV_vs_WT_F08.15809.15809.3 1.74E-14 27/128 Q.LSGAGGGGGEAGAGGGAAAVAAGGVVTTTASGK.R "sp|P56270|MAZ_HUMAN,tr|A0A087WWR2|A0A087WWR2_HUMAN" 2 2543.2576 0.66 118927 15809 3 2543.260963 848.7598 Myc-associated zinc finger protein OS=Homo sapiens OX=9606 GN=MAZ PE=1 SV=1 6 2763.7 - 500334 - - - 1.3333 - 4.918 0.738 - 635.4 1 1 0 0.0034 33 0 0 0 4.50E+06 6.77E+06 - - - 10.4317 1 221125_WJC_METTL3_EV_vs_WT_F08.15813.15813.4 6.78E-09 18/114 R.LKPDEGGEVPVLNVSYKPQK.L "sp|P61221|ABCE1_HUMAN,tr|D6R9I9|D6R9I9_HUMAN" 2 2196.179 1.08 118930 15813 4 2196.181181 550.052 ATP-binding cassette sub-family E member 1 OS=Homo sapiens OX=9606 GN=ABCE1 PE=1 SV=1 6.18 2764.1 - 2.25E+06 - - - 0.9776 - 3.042 0.598 - 238.2 1 2 0 0.0021 20 0 0 0 5.73E+07 5.28E+07 - - - 4.8023 0.9986 221125_WJC_METTL3_EV_vs_WT_F08.15816.15816.4 0.000199 15/84 R.STSHK[136.11]PDEIYGMIER[166.11].L sp|Q86U44|MTA70_HUMAN 1 1779.8581 0.01 118933 15816 4 1779.855981 445.9718 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 5.42 2764.5 - 953135 - - - -1.1647 - 2.328 0.275 - 164.2 1 2 0 -0.0021 15 0 0 0 3.18E+05 3.56E+07 - - - 1.9214 1 221125_WJC_METTL3_EV_vs_WT_F08.15818.15818.4 3.44E-08 16/144 R.SEAEEAITSFNGHK[136.11]PPGSSEPITVK[136.11].F sp|Q15717|ELAV1_HUMAN 1 2627.305 1.64 118935 15818 4 2627.302526 657.8335 ELAV-like protein 1 OS=Homo sapiens OX=9606 GN=ELAVL1 PE=1 SV=2 4.9 2764.7 - 781588 - - - -0.9325 - 3.242 0.528 - 109.4 1 2 0 -0.0024 25 0 0 0 9.30E+07 5.66E+07 - - - 4.1952 0.9997 221125_WJC_METTL3_EV_vs_WT_F08.15819.15819.3 0.000187 15/92 K.ELQQAQTTR[166.11]PESTQIQPQPGFC[160.03]IK[136.11].T "sp|Q9NWS0|PIHD1_HUMAN,tr|M0QYF4|M0QYF4_HUMAN,tr|M0QXD5|M0QXD5_HUMAN,tr|M0R3A8|M0R3A8_HUMAN,tr|M0R0J2|M0R0J2_HUMAN,tr|M0QYA2|M0QYA2_HUMAN" 6 2802.4089 1.47 118936 15819 3 2802.404872 935.1436 PIH1 domain-containing protein 1 OS=Homo sapiens OX=9606 GN=PIH1D1 PE=1 SV=1 6.23 2764.9 - 354492 - - - -1.4545 - 2.781 0.328 - 131.7 1 2 0 -0.0041 24 0 0 0 4.03E+08 2.74E+08 - - - 4.5713 0.9997 221125_WJC_METTL3_EV_vs_WT_F08.15821.15821.3 1.95E-05 Nov-60 K.VILHLK[136.11]EDQTEYLEER[166.11].R "sp|P08238|HS90B_HUMAN,sp|Q58FF6|H90B4_HUMAN,sp|Q58FF7|H90B3_HUMAN,sp|P07900|HS90A_HUMAN,tr|G3V2J8|G3V2J8_HUMAN" 5 2032.0596 0.41 118937 15821 3 2032.06357 678.3605 Heat shock protein HSP 90-beta OS=Homo sapiens OX=9606 GN=HSP90AB1 PE=1 SV=4 4.57 2765.1 - 416055 - - - 1.9581 - 2.309 0.513 - 181.2 1 2 1 0.004 16 0 0 0 3.13E+06 7.64E+06 - - - 6.4055 1 221125_WJC_METTL3_EV_vs_WT_F08.15823.15823.3 3.66E-06 25/92 K.ELQQAQTTRPESTQIQPQPGFC[160.03]IK.T "sp|Q9NWS0|PIHD1_HUMAN,tr|M0QYF4|M0QYF4_HUMAN,tr|M0QXD5|M0QXD5_HUMAN,tr|M0R3A8|M0R3A8_HUMAN,tr|M0R0J2|M0R0J2_HUMAN,tr|M0QYA2|M0QYA2_HUMAN" 6 2784.3865 1.47 118938 15823 3 2784.386116 929.1361 PIH1 domain-containing protein 1 OS=Homo sapiens OX=9606 GN=PIH1D1 PE=1 SV=1 6.23 2765.3 - 735071 - - - -0.13 - 3.916 0.515 - 386.3 1 2 0 -0.0004 24 0 0 0 4.03E+08 2.74E+08 - - - 7.4522 1 221125_WJC_METTL3_EV_vs_WT_F08.15825.15825.3 4.95E-10 19/64 K.GYPHLC[160.03]SIC[160.03]DLPVHSNK[136.11].E "sp|P43243|MATR3_HUMAN,tr|A8MXP9|A8MXP9_HUMAN,tr|D6R991|D6R991_HUMAN,tr|A0A0R4J2E8|A0A0R4J2E8_HUMAN,tr|H0Y8T4|H0Y8T4_HUMAN,tr|D6REM6|D6REM6_HUMAN" 6 2003.9437 1.34 118940 15825 3 2003.942768 668.9885 Matrin-3 OS=Homo sapiens OX=9606 GN=MATR3 PE=1 SV=2 6.9 2765.5 - 2.02E+06 - - - -0.4661 - 3.305 0.672 - 379.1 1 2 0 -0.0009 17 0 0 0 6.43E+08 4.81E+08 - - - 9.0519 1 221125_WJC_METTL3_EV_vs_WT_F08.15826.15826.2 4.18E-11 20/40 R.R[166.11]VNSASSSNPPAEVDPDTILK[136.11].A "sp|Q9BY77|PDIP3_HUMAN,tr|F6VRR5|F6VRR5_HUMAN" 2 2214.1247 1.75 118941 15826 2 2214.122804 1108.0696 Polymerase delta-interacting protein 3 OS=Homo sapiens OX=9606 GN=POLDIP3 PE=1 SV=2 4.56 2765.6 - 415181 - - - -0.8608 - 3.292 0.665 - 686.4 1 2 0 -0.0019 21 0 0 0 3.62E+07 2.07E+07 - - - 6.8814 1 221125_WJC_METTL3_EV_vs_WT_F08.15831.15831.4 2.31E-06 18/96 K.HHSLGGQYGVQGFPTIK.L sp|Q15084|PDIA6_HUMAN 1 1824.9271 1.26 118944 15831 4 1824.927105 457.2391 Protein disulfide-isomerase A6 OS=Homo sapiens OX=9606 GN=PDIA6 PE=1 SV=1 8.61 2766.3 - 500941 - - - -0.0066 - 2.502 0.482 - 166.3 1 2 0 0 17 0 0 0 1.02E+07 8.07E+06 - - - 3.7397 0.9997 221125_WJC_METTL3_EV_vs_WT_F08.15832.15832.3 1.94E-05 15/60 K.TDEDEK[136.11]TILNLENSNK[136.11].S sp|Q8IX12|CCAR1_HUMAN 1 1877.9189 5.57 118945 15832 3 1877.913638 626.9802 Cell division cycle and apoptosis regulator protein 1 OS=Homo sapiens OX=9606 GN=CCAR1 PE=1 SV=2 4.18 2766.4 - 972558 - - - -2.8106 - 2.868 0.527 - 309.1 1 2 1 -0.0053 16 0 0 0 8.21E+07 1.47E+07 - - - 7.1175 1 221125_WJC_METTL3_EV_vs_WT_F08.15839.15839.3 1.37E-10 19/64 K.GYPHLC[160.03]SIC[160.03]DLPVHSNK.E "sp|P43243|MATR3_HUMAN,tr|A8MXP9|A8MXP9_HUMAN,tr|D6R991|D6R991_HUMAN,tr|A0A0R4J2E8|A0A0R4J2E8_HUMAN,tr|H0Y8T4|H0Y8T4_HUMAN,tr|D6REM6|D6REM6_HUMAN" 6 1995.9295 1.34 118950 15839 3 1995.929739 666.3171 Matrin-3 OS=Homo sapiens OX=9606 GN=MATR3 PE=1 SV=2 6.9 2767.3 - 3.81E+06 - - - 0.1187 - 3.378 0.654 - 426.6 1 2 0 0.0002 17 0 0 0 6.43E+08 4.81E+08 - - - 8.9066 1 221125_WJC_METTL3_EV_vs_WT_F08.15840.15840.2 2.25E-05 19/40 R.RVNSASSSNPPAEVDPDTILK.A "sp|Q9BY77|PDIP3_HUMAN,tr|F6VRR5|F6VRR5_HUMAN" 2 2196.1022 1.75 118951 15840 2 2196.101069 1099.0584 Polymerase delta-interacting protein 3 OS=Homo sapiens OX=9606 GN=POLDIP3 PE=1 SV=2 4.56 2767.4 - 825754 - - - -0.5332 - 3.321 0.587 - 583.6 1 2 0 -0.0012 21 0 0 0 3.62E+07 2.07E+07 - - - 6.3271 1 221125_WJC_METTL3_EV_vs_WT_F08.15843.15843.3 7.15E-08 17/96 R.SEAEEAITSFNGHKPPGSSEPITVK.F sp|Q15717|ELAV1_HUMAN 1 2611.2766 1.85 118954 15843 3 2611.27365 871.4328 ELAV-like protein 1 OS=Homo sapiens OX=9606 GN=ELAVL1 PE=1 SV=2 4.9 2767.8 - 511441 - - - -1.1205 - 3.377 0.625 - 221.7 1 2 0 -0.0029 25 0 0 0 1.68E+07 9.11E+06 - - - 8.3072 0.9563 221125_WJC_METTL3_EV_vs_WT_F08.15844.15844.3 0.52 Jun-88 K.APVPSTC[160.03]SSTFPEELSPPSHQAK[136.11].R "sp|Q14980|NUMA1_HUMAN,tr|A0A087WY61|A0A087WY61_HUMAN,tr|F5H763|F5H763_HUMAN,tr|F5H0Z7|F5H0Z7_HUMAN,tr|F5H4J1|F5H4J1_HUMAN,tr|F5H6Y5|F5H6Y5_HUMAN" 6 2461.1675 1.09 118955 15844 3 2461.168499 821.3964 Nuclear mitotic apparatus protein 1 OS=Homo sapiens OX=9606 GN=NUMA1 PE=1 SV=2 5.4 2767.9 - 265235 - - - 0.41 - 1.319 0.169 - 18.4 2 2 0 0.001 23 0 0 0 3.06E+06 2.79E+06 - - - 0.9341 0.9996 221125_WJC_METTL3_EV_vs_WT_F08.15845.15845.2 0.000132 Jun-32 K.ANELPQPPVPEPANAGK.R "sp|P78347|GTF2I_HUMAN,tr|A0A494C1K3|A0A494C1K3_HUMAN" 2 1727.8842 11.2 118956 15845 2 1727.885453 864.9494 General transcription factor II-I OS=Homo sapiens OX=9606 GN=GTF2I PE=1 SV=2 4.53 2768.1 - 221488 - - - 0.6968 - 1.563 0.437 - 93.8 1 2 0 0.0012 17 0 0 0 4.66E+06 4.16E+05 - - - 3.3663 1 221125_WJC_METTL3_EV_vs_WT_F08.15849.15849.2 3.89E-08 15/22 A.VPELATDPELEK[136.11].K "sp|Q86U44|MTA70_HUMAN,tr|B4E349|B4E349_HUMAN,tr|F5H6D8|F5H6D8_HUMAN,tr|H0YFV6|H0YFV6_HUMAN,tr|B4DTN4|B4DTN4_HUMAN" 5 1347.7013 0.001 118958 15849 2 1347.700329 674.8579 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 4 2768.6 - 1.32E+06 - - - -0.7294 - 2.88 0.621 - 539.4 1 1 0 -0.001 12 0 0 0 0.00E+00 3.64E+07 - - - 6.4106 1 221125_WJC_METTL3_EV_vs_WT_F08.15853.15853.4 6.67E-08 20/90 K.K[136.11]HLEINPDHSIIETLR[166.11].Q sp|P07900|HS90A_HUMAN 1 1932.0548 0.6 118962 15853 4 1932.054373 484.021 Heat shock protein HSP 90-alpha OS=Homo sapiens OX=9606 GN=HSP90AA1 PE=1 SV=5 6.01 2769.1 - 523911 - - - -0.2107 - 3.217 0.529 - 495.9 1 2 0 -0.0004 16 0 0 0 2.54E+07 4.24E+07 - - - 4.2419 1 221125_WJC_METTL3_EV_vs_WT_F08.15854.15854.3 4.69E-07 16/96 R.SEAEEAITSFNGHK[136.11]PPGSSEPITVK[136.11].F sp|Q15717|ELAV1_HUMAN 1 2627.305 1.85 118963 15854 3 2627.306959 876.7756 ELAV-like protein 1 OS=Homo sapiens OX=9606 GN=ELAVL1 PE=1 SV=2 4.9 2769.2 - 385554 - - - 0.7548 - 3.118 0.599 - 86.7 1 2 0 0.002 25 0 0 0 1.68E+07 9.11E+06 - - - 7.834 0.9972 221125_WJC_METTL3_EV_vs_WT_F08.15855.15855.4 0.00724 Sep-90 K.FILAPAKQEDEWDKPR.L sp|P13674|P4HA1_HUMAN 1 1941.9949 1.64 118964 15855 4 1941.995193 486.506 Prolyl 4-hydroxylase subunit alpha-1 OS=Homo sapiens OX=9606 GN=P4HA1 PE=1 SV=2 4.78 2769.3 - 343139 - - - 0.1704 - 1.703 0.32 - 43.5 1 2 1 0.0003 16 0 0 0 2.18E+06 1.33E+06 - - - 2.1987 0.9988 221125_WJC_METTL3_EV_vs_WT_F08.15858.15858.4 0.0277 18/138 K.ELQQAQTTR[166.11]PESTQIQPQPGFC[160.03]IK[136.11].T "sp|Q9NWS0|PIHD1_HUMAN,tr|M0QYF4|M0QYF4_HUMAN,tr|M0QXD5|M0QXD5_HUMAN,tr|M0R3A8|M0R3A8_HUMAN,tr|M0R0J2|M0R0J2_HUMAN,tr|M0QYA2|M0QYA2_HUMAN" 6 2802.4089 1.48 118965 15858 4 2802.407817 701.6095 PIH1 domain-containing protein 1 OS=Homo sapiens OX=9606 GN=PIH1D1 PE=1 SV=1 6.23 2769.7 - 2.14E+06 - - - -0.4036 - 2.758 0.277 - 98.6 1 2 0 -0.0011 24 0 0 0 8.25E+07 5.56E+07 - - - 1.9623 0.9997 221125_WJC_METTL3_EV_vs_WT_F08.15860.15860.4 6.72E-05 19/114 K.IKPHLMSQELPEDWDKQPVK.V "sp|P07237|PDIA1_HUMAN,tr|A0A7P0TA97|A0A7P0TA97_HUMAN,tr|A0A7P0T8C0|A0A7P0T8C0_HUMAN,tr|H7BZ94|H7BZ94_HUMAN,tr|B3KTQ9|B3KTQ9_HUMAN,tr|A0A7P0TA71|A0A7P0TA71_HUMAN,tr|I3L4M2|I3L4M2_HUMAN,tr|A0A7P0T9D6|A0A7P0T9D6_HUMAN,tr|A0A7P0T9K9|A0A7P0T9K9_HUMAN,tr|H0Y3Z3|H0Y3Z3_HUMAN,tr|A0A7P0TA35|A0A7P0TA35_HUMAN,tr|A0A7P0TB26|A0A7P0TB26_HUMAN,tr|A0A7P0T9U6|A0A7P0T9U6_HUMAN,tr|I3L0S0|I3L0S0_HUMAN,tr|I3L3P5|I3L3P5_HUMAN,tr|A0A7P0T8J3|A0A7P0T8J3_HUMAN,tr|A0A7P0T8X1|A0A7P0T8X1_HUMAN" 17 2417.2413 1.34 118967 15860 4 2417.242494 605.3176 Protein disulfide-isomerase OS=Homo sapiens OX=9606 GN=P4HB PE=1 SV=3 5.48 2770 - 815371 - - - 0.4869 - 2.592 0.443 - 243.8 1 2 1 0.0012 20 0 0 0 1.63E+07 1.22E+07 - - - 3.4 1 221125_WJC_METTL3_EV_vs_WT_F08.15862.15862.3 3.53E-12 20/64 R.HTLEQHNWNIEAAVQDR.L "sp|Q96CS3|FAF2_HUMAN,tr|D6RBG6|D6RBG6_HUMAN" 2 2059.9824 1.31 118969 15862 3 2059.983075 687.6681 FAS-associated factor 2 OS=Homo sapiens OX=9606 GN=FAF2 PE=1 SV=2 5.27 2770.2 - 669690 - - - 0.3277 - 4.204 0.562 - 715.1 1 2 0 0.0007 17 0 0 0 1.70E+07 1.30E+07 - - - 8.4334 1 221125_WJC_METTL3_EV_vs_WT_F08.15867.15867.4 1.17E-08 17/126 K.SHLMSLYSAC[160.03]SSEVPHGPVDQK[136.11].F sp|O95816|BAG2_HUMAN 1 2436.1293 0.43 118972 15867 4 2436.126321 610.0396 BAG family molecular chaperone regulator 2 OS=Homo sapiens OX=9606 GN=BAG2 PE=1 SV=1 5.94 2770.8 - 1.47E+06 - - - -1.2352 - 3.082 0.585 - 179.8 1 2 0 -0.003 22 0 0 0 8.30E+06 1.93E+07 - - - 4.6853 0.9988 221125_WJC_METTL3_EV_vs_WT_F08.15871.15871.4 0.0038 23/138 K.ELQQAQTTRPESTQIQPQPGFC[160.03]IK.T "sp|Q9NWS0|PIHD1_HUMAN,tr|M0QYF4|M0QYF4_HUMAN,tr|M0QXD5|M0QXD5_HUMAN,tr|M0R3A8|M0R3A8_HUMAN,tr|M0R0J2|M0R0J2_HUMAN,tr|M0QYA2|M0QYA2_HUMAN" 6 2784.3865 1.48 118975 15871 4 2784.38594 697.1039 PIH1 domain-containing protein 1 OS=Homo sapiens OX=9606 GN=PIH1D1 PE=1 SV=1 6.23 2771.3 - 4.17E+06 - - - -0.1932 - 2.66 0.278 - 170.3 1 2 0 -0.0005 24 0 0 0 8.25E+07 5.56E+07 - - - 1.9596 0.9999 221125_WJC_METTL3_EV_vs_WT_F08.15875.15875.3 5.10E-09 21/64 R.HTLEQHNWNIEAAVQDR[166.11].L "sp|Q96CS3|FAF2_HUMAN,tr|D6RBG6|D6RBG6_HUMAN" 2 2069.9907 1.3 118977 15875 3 2069.98381 691.0042 FAS-associated factor 2 OS=Homo sapiens OX=9606 GN=FAF2 PE=1 SV=2 5.27 2771.7 - 583457 - - - -3.314 - 3.801 0.499 - 782.2 1 2 0 -0.0069 17 0 0 0 1.68E+07 1.30E+07 - - - 7.4747 1 221125_WJC_METTL3_EV_vs_WT_F08.15876.15876.4 5.59E-08 19/90 K.KHLEINPDHSIIETLR.Q sp|P07900|HS90A_HUMAN 1 1914.0323 0.6 118978 15876 4 1914.03041 479.5154 Heat shock protein HSP 90-alpha OS=Homo sapiens OX=9606 GN=HSP90AA1 PE=1 SV=5 6.01 2771.8 - 930234 - - - -0.9927 - 3.232 0.62 - 424.7 1 2 0 -0.0019 16 0 0 0 2.54E+07 4.24E+07 - - - 5.0352 0.9996 221125_WJC_METTL3_EV_vs_WT_F08.15877.15877.4 2.68E-05 15/84 K.FKVESEQQYFEIEKR.L "sp|P12270|TPR_HUMAN,tr|Q5SWX9|Q5SWX9_HUMAN" 2 1958.9738 3.59 118979 15877 4 1958.977733 490.7507 Nucleoprotein TPR OS=Homo sapiens OX=9606 GN=TPR PE=1 SV=3 4.95 2771.9 - 548154 - - - 2.0118 - 2.855 0.44 - 243.4 1 2 1 0.0039 15 0 0 0 8.65E+06 2.41E+06 - - - 3.43 1 221125_WJC_METTL3_EV_vs_WT_F08.15878.15878.4 2.83E-07 15/96 R.AHHVYPSLPTPLLRPSR.R sp|Q96HA1|P121A_HUMAN 1 1940.0745 0.26 118980 15878 4 1940.076142 486.0259 Nuclear envelope pore membrane protein POM 121 OS=Homo sapiens OX=9606 GN=POM121 PE=1 SV=2 10.84 2772 - 366156 - - - 0.8721 - 2.446 0.534 - 140.5 1 2 0 0.0017 17 0 0 0 8.16E+06 3.11E+07 - - - 4.184 0.9997 221125_WJC_METTL3_EV_vs_WT_F08.15879.15879.4 1.87E-07 17/102 K.KLISVETDIVVDHYKEEK.F "sp|Q12931|TRAP1_HUMAN,tr|I3L0K7|I3L0K7_HUMAN" 2 2144.1365 2.34 118981 15879 4 2144.138418 537.0414 "Heat shock protein 75 kDa, mitochondrial OS=Homo sapiens OX=9606 GN=TRAP1 PE=1 SV=3" 4.9 2772.2 - 320716 - - - 0.8941 - 3.546 0.429 - 305.9 1 2 1 0.0019 18 0 0 0 5.30E+06 2.27E+06 - - - 3.3931 1 221125_WJC_METTL3_EV_vs_WT_F08.15883.15883.4 1.03E-07 20/138 K.QTAISQPASGNTFSHHSMVSMLGK.G "sp|Q14157|UBP2L_HUMAN,tr|F8W726|F8W726_HUMAN" 2 2515.1948 2.11 118983 15883 4 2515.189024 629.806 Ubiquitin-associated protein 2-like OS=Homo sapiens OX=9606 GN=UBAP2L PE=1 SV=2 8.76 2772.7 - 822347 - - - -2.2873 - 3.106 0.527 - 122.3 1 2 0 -0.0058 24 0 0 0 1.06E+09 5.02E+08 - - - 4.1752 0.9999 221125_WJC_METTL3_EV_vs_WT_F08.15886.15886.3 1.01E-07 21/84 R.AVKPEPTNSSVEVSPDIYQQVR.D "sp|Q9UPW6|SATB2_HUMAN,tr|C9JR56|C9JR56_HUMAN" 2 2442.2391 9.6 118986 15886 3 2442.232248 815.087 DNA-binding protein SATB2 OS=Homo sapiens OX=9606 GN=SATB2 PE=1 SV=2 4.68 2773.1 - 416728 - - - -2.7925 - 3.174 0.522 - 297.9 1 2 0 -0.0068 22 0 0 0 9.53E+06 9.93E+05 - - - 7.0962 1 221125_WJC_METTL3_EV_vs_WT_F08.15890.15890.3 1.75E-10 23/96 K.LVQDVANNTNEEAGDGTTTATVLAR[166.11].S "sp|P10809|CH60_HUMAN,tr|C9JL25|C9JL25_HUMAN,tr|A0A7I2V2X6|A0A7I2V2X6_HUMAN,tr|A0A7I2YQK6|A0A7I2YQK6_HUMAN,tr|A0A7I2V599|A0A7I2V599_HUMAN,tr|E7EXB4|E7EXB4_HUMAN,tr|A0A7I2YQ71|A0A7I2YQ71_HUMAN,tr|E7ESH4|E7ESH4_HUMAN,tr|A0A7I2V5M1|A0A7I2V5M1_HUMAN,tr|A0A7I2V5K3|A0A7I2V5K3_HUMAN,tr|A0A7I2V369|A0A7I2V369_HUMAN" 11 2569.2495 1.39 118988 15890 3 2569.245905 857.4238 "60 kDa heat shock protein, mitochondrial OS=Homo sapiens OX=9606 GN=HSPD1 PE=1 SV=2" 3.92 2773.6 - 1.21E+06 - - - -1.4082 - 4.081 0.686 - 485.3 1 2 0 -0.0036 25 0 0 0 1.97E+08 1.42E+08 - - - 9.4227 1 221125_WJC_METTL3_EV_vs_WT_F08.15891.15891.3 4.76E-14 21/96 K.LVQDVANNTNEEAGDGTTTATVLAR.S "sp|P10809|CH60_HUMAN,tr|C9JL25|C9JL25_HUMAN,tr|A0A7I2V2X6|A0A7I2V2X6_HUMAN,tr|A0A7I2YQK6|A0A7I2YQK6_HUMAN,tr|A0A7I2V599|A0A7I2V599_HUMAN,tr|E7EXB4|E7EXB4_HUMAN,tr|A0A7I2YQ71|A0A7I2YQ71_HUMAN,tr|E7ESH4|E7ESH4_HUMAN,tr|A0A7I2V5M1|A0A7I2V5M1_HUMAN,tr|A0A7I2V5K3|A0A7I2V5K3_HUMAN,tr|A0A7I2V369|A0A7I2V369_HUMAN" 11 2559.2413 1.4 118989 15891 3 2559.23864 854.0877 "60 kDa heat shock protein, mitochondrial OS=Homo sapiens OX=9606 GN=HSPD1 PE=1 SV=2" 3.92 2773.8 - 1.22E+06 - - - -1.021 - 3.848 0.714 - 532.8 1 2 0 -0.0026 25 0 0 0 1.98E+08 1.42E+08 - - - 9.5999 1 221125_WJC_METTL3_EV_vs_WT_F08.15893.15893.4 3.08E-11 28/138 K.QTAISQPASGNTFSHHSMVSMLGK[136.11].G "sp|Q14157|UBP2L_HUMAN,tr|F8W726|F8W726_HUMAN" 2 2523.209 2.11 118991 15893 4 2523.206403 631.8095 Ubiquitin-associated protein 2-like OS=Homo sapiens OX=9606 GN=UBAP2L PE=1 SV=2 8.76 2773.9 - 1.27E+06 - - - -1.0201 - 5.246 0.63 - 755.9 1 2 0 -0.0026 24 0 0 0 1.06E+09 5.02E+08 - - - 5.2408 1 221125_WJC_METTL3_EV_vs_WT_F08.15903.15903.3 6.30E-10 22/92 K.QTAISQPASGNTFSHHSMVSMLGK.G "sp|Q14157|UBP2L_HUMAN,tr|F8W726|F8W726_HUMAN" 2 2515.1948 2.7 118997 15903 3 2515.194362 839.4055 Ubiquitin-associated protein 2-like OS=Homo sapiens OX=9606 GN=UBAP2L PE=1 SV=2 8.76 2775.3 - 1.30E+06 - - - -0.165 - 4.253 0.608 - 487.1 1 2 0 -0.0004 24 0 0 0 2.25E+08 8.33E+07 - - - 8.6807 1 221125_WJC_METTL3_EV_vs_WT_F08.15906.15906.3 5.11E-07 21/92 K.QTAISQPASGNTFSHHSMVSMLGK[136.11].G "sp|Q14157|UBP2L_HUMAN,tr|F8W726|F8W726_HUMAN" 2 2523.209 2.65 119000 15906 3 2523.20299 842.0769 Ubiquitin-associated protein 2-like OS=Homo sapiens OX=9606 GN=UBAP2L PE=1 SV=2 8.76 2775.6 - 762779 - - - -2.3728 - 3.913 0.57 - 407.7 1 2 0 -0.006 24 0 0 0 2.20E+08 8.27E+07 - - - 8.062 0.9989 221125_WJC_METTL3_EV_vs_WT_F08.15908.15908.4 0.000531 16/96 K.LDK[136.11]SQIHDIVLVGGSTR[166.11].L "sp|P11142|HSP7C_HUMAN,tr|E9PNE6|E9PNE6_HUMAN,tr|A8K7Q2|A8K7Q2_HUMAN,tr|E9PKE3|E9PKE3_HUMAN,tr|E9PN89|E9PN89_HUMAN" 5 1855.0282 0.87 119002 15908 4 1855.026251 464.7643 Heat shock cognate 71 kDa protein OS=Homo sapiens OX=9606 GN=HSPA8 PE=1 SV=1 6.75 2775.9 - 486076 - - - -1.0674 - 2.815 0.351 - 167.1 1 2 1 -0.002 17 0 0 0 4.31E+07 4.97E+07 - - - 2.6399 1 221125_WJC_METTL3_EV_vs_WT_F08.15915.15915.3 4.39E-11 22/88 R.GYDSAGVGFDGGNDKDWEANAC[160.03]K.L "sp|Q06210|GFPT1_HUMAN,tr|A0A6I8PTT9|A0A6I8PTT9_HUMAN" 2 2431.9975 1.36 119007 15915 3 2431.995425 811.6731 Glutamine--fructose-6-phosphate aminotransferase [isomerizing] 1 OS=Homo sapiens OX=9606 GN=GFPT1 PE=1 SV=3 4.04 2776.8 - 1.05E+06 - - - -0.8606 - 4.21 0.784 - 327.5 1 2 1 -0.0021 23 0 0 0 9.20E+07 6.78E+07 - - - 10.6525 0.9987 221125_WJC_METTL3_EV_vs_WT_F08.15918.15918.2 0.0104 14-Sep R.LPLQDVYK.L "sp|Q05639|EF1A2_HUMAN,sp|P68104|EF1A1_HUMAN,sp|Q5VTE0|EF1A3_HUMAN,tr|A0A7I2V659|A0A7I2V659_HUMAN,tr|A0A7I2V3H3|A0A7I2V3H3_HUMAN,tr|A0A2U3TZH3|A0A2U3TZH3_HUMAN,tr|A0A7I2V5N4|A0A7I2V5N4_HUMAN,tr|A0A087WVQ9|A0A087WVQ9_HUMAN,tr|A0A087WV01|A0A087WV01_HUMAN" 9 974.5437 8.49 119010 15918 2 974.541308 488.2791 Elongation factor 1-alpha 2 OS=Homo sapiens OX=9606 GN=EEF1A2 PE=1 SV=1 5.83 2777.2 - 343119 - - - -2.437 - 1.73 0.332 - 222.9 1 2 0 -0.0024 8 0 0 0 2.42E+07 2.85E+06 - - - 3.1455 0.9999 221125_WJC_METTL3_EV_vs_WT_F08.15921.15921.4 3.29E-05 17/90 R.TTSNTLHYIHIEQLDK[136.11].L sp|Q7Z6Z7|HUWE1_HUMAN 1 1919.9832 0.49 119011 15921 4 1919.983456 481.0031 E3 ubiquitin-protein ligase HUWE1 OS=Homo sapiens OX=9606 GN=HUWE1 PE=1 SV=3 5.92 2777.6 - 1.06E+06 - - - 0.112 - 3.38 0.434 - 324.3 1 2 0 0.0002 16 0 0 0 4.55E+06 9.35E+06 - - - 3.4325 0.9999 221125_WJC_METTL3_EV_vs_WT_F08.15924.15924.4 0.000515 14/90 R.LSFPSIKPDTDQTLKK.E "sp|Q92785|REQU_HUMAN,tr|J3KMZ8|J3KMZ8_HUMAN" 2 1816.9935 1.06 119014 15924 4 1816.99182 455.2556 Zinc finger protein ubi-d4 OS=Homo sapiens OX=9606 GN=DPF2 PE=1 SV=2 8.5 2778 - 617934 - - - -0.9053 - 2.617 0.424 - 90.8 1 2 0 -0.0016 16 0 0 0 4.11E+07 3.88E+07 - - - 3.2549 0.9997 221125_WJC_METTL3_EV_vs_WT_F08.15926.15926.4 0.000645 Nov-90 R.LSFPSIK[136.11]PDTDQTLK[136.11]K[136.11].E "sp|Q92785|REQU_HUMAN,tr|J3KMZ8|J3KMZ8_HUMAN" 2 1841.0361 1.06 119016 15926 4 1841.03299 461.2663 Zinc finger protein ubi-d4 OS=Homo sapiens OX=9606 GN=DPF2 PE=1 SV=2 8.5 2778.2 - 439569 - - - -1.6703 - 2.081 0.371 - 52.4 1 2 0 -0.0031 16 0 0 0 4.11E+07 3.88E+07 - - - 2.7125 0.9996 221125_WJC_METTL3_EV_vs_WT_F08.15927.15927.3 3.21E-07 16/84 K.DHTPSQELALTQSVGGDSSADR[166.11].L "sp|Q86U44|MTA70_HUMAN,tr|H0YFV6|H0YFV6_HUMAN" 2 2280.0494 3.01 119017 15927 3 2280.035707 761.0237 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 4.22 2778.3 - 368550 - - - -5.9911 - 3.285 0.596 - 219.7 1 2 0 -0.0137 22 0 0 0 5.55E+07 1.84E+07 - - - 8.0008 0.9921 221125_WJC_METTL3_EV_vs_WT_F08.15928.15928.4 0.0827 Sep-90 R.KKEADSVYGEWVPVEK.N "sp|P18583|SON_HUMAN,tr|H7C1M2|H7C1M2_HUMAN,tr|H7C2G8|H7C2G8_HUMAN,tr|J3QSZ5|J3QSZ5_HUMAN" 4 1862.9414 2.95 119018 15928 4 1862.943986 466.7426 Protein SON OS=Homo sapiens OX=9606 GN=SON PE=1 SV=4 4.87 2778.5 - 175404 - - - 1.372 - 1.558 0.278 - 56.8 1 2 1 0.0026 16 0 0 0 2.81E+06 9.52E+05 - - - 1.8012 1 221125_WJC_METTL3_EV_vs_WT_F08.15944.15944.2 5.12E-17 18/48 K.LVQDVANNTNEEAGDGTTTATVLAR.S "sp|P10809|CH60_HUMAN,tr|C9JL25|C9JL25_HUMAN,tr|A0A7I2V2X6|A0A7I2V2X6_HUMAN,tr|A0A7I2YQK6|A0A7I2YQK6_HUMAN,tr|A0A7I2V599|A0A7I2V599_HUMAN,tr|E7EXB4|E7EXB4_HUMAN,tr|A0A7I2YQ71|A0A7I2YQ71_HUMAN,tr|E7ESH4|E7ESH4_HUMAN,tr|A0A7I2V5M1|A0A7I2V5M1_HUMAN,tr|A0A7I2V5K3|A0A7I2V5K3_HUMAN,tr|A0A7I2V369|A0A7I2V369_HUMAN" 11 2559.2413 1.53 119028 15944 2 2559.23988 1280.6279 "60 kDa heat shock protein, mitochondrial OS=Homo sapiens OX=9606 GN=HSPD1 PE=1 SV=2" 3.92 2780.5 - 496406 - - - -0.5365 - 4.413 0.786 - 784.4 1 2 0 -0.0014 25 0 0 0 7.43E+06 4.87E+06 - - - 8.4958 1 221125_WJC_METTL3_EV_vs_WT_F08.15948.15948.3 2.41E-10 25/80 R.RVNSASSSNPPAEVDPDTILK.A "sp|Q9BY77|PDIP3_HUMAN,tr|F6VRR5|F6VRR5_HUMAN" 2 2196.1022 1.68 119031 15948 3 2196.100434 733.0414 Polymerase delta-interacting protein 3 OS=Homo sapiens OX=9606 GN=POLDIP3 PE=1 SV=2 4.56 2781 - 8.59E+06 - - - -0.8224 - 3.871 0.638 - 536.5 1 2 0 -0.0018 21 0 0 0 2.41E+09 1.44E+09 - - - 8.8976 0.9999 221125_WJC_METTL3_EV_vs_WT_F08.15951.15951.4 2.20E-07 15/114 K.HAAENPGKYNILGTNTIMDK.M "sp|Q00839|HNRPU_HUMAN,tr|A0A1W2PQL0|A0A1W2PQL0_HUMAN,tr|A0A1W2PPL4|A0A1W2PPL4_HUMAN,tr|A0A1W2PQ74|A0A1W2PQ74_HUMAN,tr|Q5RI18|Q5RI18_HUMAN,tr|A0A1W2PP35|A0A1W2PP35_HUMAN,tr|A0A1W2PPS1|A0A1W2PPS1_HUMAN,tr|A0A1W2PRZ7|A0A1W2PRZ7_HUMAN,tr|A0A1W2PPH7|A0A1W2PPH7_HUMAN,tr|A0A1W2PQD4|A0A1W2PQD4_HUMAN,tr|A0A1W2PP34|A0A1W2PP34_HUMAN,tr|A0A1X7SBS1|A0A1X7SBS1_HUMAN" 12 2186.079 1.06 119033 15951 4 2186.077416 547.527 Heterogeneous nuclear ribonucleoprotein U OS=Homo sapiens OX=9606 GN=HNRNPU PE=1 SV=6 6.75 2781.3 - 2.22E+06 - - - -0.726 - 3.115 0.506 - 191.9 1 2 1 -0.0016 20 0 0 0 2.79E+08 2.63E+08 - - - 4.0096 1 221125_WJC_METTL3_EV_vs_WT_F08.15952.15952.3 1.09E-15 25/76 K.HAAENPGKYNILGTNTIMDK.M "sp|Q00839|HNRPU_HUMAN,tr|A0A1W2PQL0|A0A1W2PQL0_HUMAN,tr|A0A1W2PPL4|A0A1W2PPL4_HUMAN,tr|A0A1W2PQ74|A0A1W2PQ74_HUMAN,tr|Q5RI18|Q5RI18_HUMAN,tr|A0A1W2PP35|A0A1W2PP35_HUMAN,tr|A0A1W2PPS1|A0A1W2PPS1_HUMAN,tr|A0A1W2PRZ7|A0A1W2PRZ7_HUMAN,tr|A0A1W2PPH7|A0A1W2PPH7_HUMAN,tr|A0A1W2PQD4|A0A1W2PQD4_HUMAN,tr|A0A1W2PP34|A0A1W2PP34_HUMAN,tr|A0A1X7SBS1|A0A1X7SBS1_HUMAN" 12 2186.079 1.05 119034 15952 3 2186.076086 729.7003 Heterogeneous nuclear ribonucleoprotein U OS=Homo sapiens OX=9606 GN=HNRNPU PE=1 SV=6 6.75 2781.4 - 1.68E+06 - - - -1.3344 - 4.282 0.671 - 693 1 2 1 -0.0029 20 0 0 0 2.13E+08 2.04E+08 - - - 9.5486 0.9942 221125_WJC_METTL3_EV_vs_WT_F08.15954.15954.4 0.399 13/114 R.EDDTATEETHPVSWKPEIIK.R sp|O43660|PLRG1_HUMAN 1 2324.1172 1.38 119036 15954 4 2324.122106 582.0366 Pleiotropic regulator 1 OS=Homo sapiens OX=9606 GN=PLRG1 PE=1 SV=1 4.35 2781.6 - 300928 - - - 2.1014 - 2.536 0.232 - 100.4 1 2 0 0.0049 20 0 0 0 2.25E+07 1.63E+07 - - - 1.5551 1 221125_WJC_METTL3_EV_vs_WT_F08.15958.15958.3 2.93E-12 24/88 R.GYDSAGVGFDGGNDK[136.11]DWEANAC[160.03]K[136.11].L "sp|Q06210|GFPT1_HUMAN,tr|A0A6I8PTT9|A0A6I8PTT9_HUMAN" 2 2448.0259 1.36 119038 15958 3 2448.020911 817.0159 Glutamine--fructose-6-phosphate aminotransferase [isomerizing] 1 OS=Homo sapiens OX=9606 GN=GFPT1 PE=1 SV=3 4.04 2782.1 - 2.77E+06 - - - -2.0453 - 4.499 0.654 - 408.3 1 2 1 -0.005 23 0 0 0 9.20E+07 6.78E+07 - - - 9.358 1 221125_WJC_METTL3_EV_vs_WT_F08.15962.15962.3 8.88E-10 23/80 R.R[166.11]VNSASSSNPPAEVDPDTILK[136.11].A "sp|Q9BY77|PDIP3_HUMAN,tr|F6VRR5|F6VRR5_HUMAN" 2 2214.1247 1.68 119041 15962 3 2214.121806 739.0488 Polymerase delta-interacting protein 3 OS=Homo sapiens OX=9606 GN=POLDIP3 PE=1 SV=2 4.56 2782.5 - 2.45E+06 - - - -1.3116 - 3.447 0.636 - 447 1 2 0 -0.0029 21 0 0 0 2.41E+09 1.44E+09 - - - 8.5968 1 221125_WJC_METTL3_EV_vs_WT_F08.15964.15964.4 5.72E-07 15/96 K.GYPHLC[160.03]SIC[160.03]DLPVHSNK.E "sp|P43243|MATR3_HUMAN,tr|A8MXP9|A8MXP9_HUMAN,tr|D6R991|D6R991_HUMAN,tr|A0A0R4J2E8|A0A0R4J2E8_HUMAN,tr|H0Y8T4|H0Y8T4_HUMAN,tr|D6REM6|D6REM6_HUMAN" 6 1995.9295 1.29 119042 15964 4 1995.928026 499.9897 Matrin-3 OS=Homo sapiens OX=9606 GN=MATR3 PE=1 SV=2 6.9 2782.7 - 2.59E+07 - - - -0.7395 - 2.105 0.488 - 119.1 1 2 0 -0.0015 17 0 0 0 1.30E+09 1.01E+09 - - - 3.7316 1 221125_WJC_METTL3_EV_vs_WT_F08.15965.15965.4 3.31E-07 15/96 K.GYPHLC[160.03]SIC[160.03]DLPVHSNK[136.11].E "sp|P43243|MATR3_HUMAN,tr|A8MXP9|A8MXP9_HUMAN,tr|D6R991|D6R991_HUMAN,tr|A0A0R4J2E8|A0A0R4J2E8_HUMAN,tr|H0Y8T4|H0Y8T4_HUMAN,tr|D6REM6|D6REM6_HUMAN" 6 2003.9437 1.29 119043 15965 4 2003.939297 501.9932 Matrin-3 OS=Homo sapiens OX=9606 GN=MATR3 PE=1 SV=2 6.9 2782.8 - 2.28E+07 - - - -2.1982 - 2.203 0.567 - 109.2 1 2 0 -0.0044 17 0 0 0 1.30E+09 1.01E+09 - - - 4.4342 0.9999 221125_WJC_METTL3_EV_vs_WT_F08.15966.15966.4 9.12E-09 17/114 K.HAAENPGK[136.11]YNILGTNTIMDK[136.11].M "sp|Q00839|HNRPU_HUMAN,tr|A0A1W2PQL0|A0A1W2PQL0_HUMAN,tr|A0A1W2PPL4|A0A1W2PPL4_HUMAN,tr|A0A1W2PQ74|A0A1W2PQ74_HUMAN,tr|Q5RI18|Q5RI18_HUMAN,tr|A0A1W2PP35|A0A1W2PP35_HUMAN,tr|A0A1W2PPS1|A0A1W2PPS1_HUMAN,tr|A0A1W2PRZ7|A0A1W2PRZ7_HUMAN,tr|A0A1W2PPH7|A0A1W2PPH7_HUMAN,tr|A0A1W2PQD4|A0A1W2PQD4_HUMAN,tr|A0A1W2PP34|A0A1W2PP34_HUMAN,tr|A0A1X7SBS1|A0A1X7SBS1_HUMAN" 12 2202.1074 1.06 119044 15966 4 2202.103684 551.5341 Heterogeneous nuclear ribonucleoprotein U OS=Homo sapiens OX=9606 GN=HNRNPU PE=1 SV=6 6.75 2782.8 - 6.32E+06 - - - -1.6888 - 2.937 0.547 - 268.2 1 2 1 -0.0037 20 0 0 0 2.79E+08 2.63E+08 - - - 4.3463 1 221125_WJC_METTL3_EV_vs_WT_F08.15967.15967.3 3.65E-12 21/76 K.HAAENPGK[136.11]YNILGTNTIMDK[136.11].M "sp|Q00839|HNRPU_HUMAN,tr|A0A1W2PQL0|A0A1W2PQL0_HUMAN,tr|A0A1W2PPL4|A0A1W2PPL4_HUMAN,tr|A0A1W2PQ74|A0A1W2PQ74_HUMAN,tr|Q5RI18|Q5RI18_HUMAN,tr|A0A1W2PP35|A0A1W2PP35_HUMAN,tr|A0A1W2PPS1|A0A1W2PPS1_HUMAN,tr|A0A1W2PRZ7|A0A1W2PRZ7_HUMAN,tr|A0A1W2PPH7|A0A1W2PPH7_HUMAN,tr|A0A1W2PQD4|A0A1W2PQD4_HUMAN,tr|A0A1W2PP34|A0A1W2PP34_HUMAN,tr|A0A1X7SBS1|A0A1X7SBS1_HUMAN" 12 2202.1074 1.05 119045 15967 3 2202.102102 735.0431 Heterogeneous nuclear ribonucleoprotein U OS=Homo sapiens OX=9606 GN=HNRNPU PE=1 SV=6 6.75 2782.9 - 3.87E+06 - - - -2.4072 - 3.946 0.663 - 382.4 1 2 1 -0.0053 20 0 0 0 2.13E+08 2.03E+08 - - - 9.2605 1 221125_WJC_METTL3_EV_vs_WT_F08.15968.15968.3 1.95E-07 22/128 K.LASVPAGGAVAVSAAPGSAAPAAGSAPAAAEEK.K "sp|P05387|RLA2_HUMAN,tr|H0YDD8|H0YDD8_HUMAN" 2 2773.4246 1.78 119046 15968 3 2773.424812 925.4822 60S acidic ribosomal protein P2 OS=Homo sapiens OX=9606 GN=RPLP2 PE=1 SV=1 4.53 2783 - 735918 - - - 0.0631 - 3.409 0.6 - 245.6 1 2 0 0.0002 33 0 0 0 1.51E+08 8.51E+07 - - - 8.0509 1 221125_WJC_METTL3_EV_vs_WT_F08.15978.15978.2 2.43E-14 25/36 R.GLLQDDAHPTLVTYADHSK[136.11].L "sp|Q86U44|MTA70_HUMAN,tr|F5H6D8|F5H6D8_HUMAN,tr|H0YFV6|H0YFV6_HUMAN,tr|B4DTN4|B4DTN4_HUMAN" 4 2088.0367 0 119051 15978 2 2088.028028 1045.0256 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 5.13 2784.3 - 1.79E+06 - - - -4.169 - 4.08 0.705 - 1647.4 1 2 0 -0.0087 19 0 0 0 6.06E+05 4.15E+08 - - - 7.7024 0.7687 221125_WJC_METTL3_EV_vs_WT_F08.15982.15982.4 1.98E-06 17/96 L.LQDDAHPTLVTYADHSK[136.11].L "sp|Q86U44|MTA70_HUMAN,tr|F5H6D8|F5H6D8_HUMAN,tr|H0YFV6|H0YFV6_HUMAN,tr|B4DTN4|B4DTN4_HUMAN" 4 1917.9312 0.02 119053 15982 4 1917.916707 480.4901 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 5.13 2784.8 - 2.13E+06 - - - -7.5597 - 2.951 0.496 - 186.2 1 1 0 -0.0145 17 0 0 0 2.56E+06 1.53E+08 - - - 3.9149 1 221125_WJC_METTL3_EV_vs_WT_F08.15988.15988.3 1.03E-06 19/56 R.RFELYFQGPSSNKPR.V "sp|P33993|MCM7_HUMAN,tr|C9J8M6|C9J8M6_HUMAN" 2 1824.9271 0.85 119058 15988 3 1824.927037 609.3163 DNA replication licensing factor MCM7 OS=Homo sapiens OX=9606 GN=MCM7 PE=1 SV=4 9.99 2785.4 - 918538 - - - -0.0438 - 3.191 0.424 - 602.1 1 2 0 -0.0001 15 0 0 0 1.76E+07 2.08E+07 - - - 6.2949 0.9913 221125_WJC_METTL3_EV_vs_WT_F08.15991.15991.3 7.07E-06 15/64 L.LQDDAHPTLVTYADHSK[136.11].L "sp|Q86U44|MTA70_HUMAN,tr|F5H6D8|F5H6D8_HUMAN,tr|H0YFV6|H0YFV6_HUMAN,tr|B4DTN4|B4DTN4_HUMAN" 4 1917.9312 0.01 119059 15991 3 1917.92476 640.3177 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 5.13 2785.7 - 1.08E+07 - - - -3.3609 - 2.909 0.544 - 281 1 1 0 -0.0064 17 0 0 0 9.90E+06 8.50E+08 - - - 7.3009 0.9964 221125_WJC_METTL3_EV_vs_WT_F08.15995.15995.3 0.149 29/128 K.LASVPAGGAVAVSAAPGSAAPAAGSAPAAAEEK[136.11].K "sp|P05387|RLA2_HUMAN,tr|H0YDD8|H0YDD8_HUMAN" 2 2781.4388 1.78 119061 15995 3 2782.43704 928.1536 60S acidic ribosomal protein P2 OS=Homo sapiens OX=9606 GN=RPLP2 PE=1 SV=1 4.53 2786.2 - 1.73E+06 - - - 358.8801 - 3.732 0.374 - 360.9 1 2 0 0.9982 33 0 0 0 1.51E+08 8.51E+07 - - - 5.463 0.9999 221125_WJC_METTL3_EV_vs_WT_F08.15997.15997.4 8.60E-06 17/96 K.K[136.11]YFLHDDR[166.11]DDGVDYWAK[136.11].R "sp|Q9NYF8|BCLF1_HUMAN,tr|H0YF14|H0YF14_HUMAN" 2 2168.0173 0.35 119062 15997 4 2168.014721 543.0116 Bcl-2-associated transcription factor 1 OS=Homo sapiens OX=9606 GN=BCLAF1 PE=1 SV=2 4.66 2786.4 - 3.29E+06 - - - -1.2076 - 2.948 0.55 - 154.8 1 2 1 -0.0026 17 0 0 0 1.64E+08 4.75E+08 - - - 4.3878 1 221125_WJC_METTL3_EV_vs_WT_F08.16005.16005.3 5.17E-11 19/56 Q.DDAHPTLVTYADHSK[136.11].L "sp|Q86U44|MTA70_HUMAN,tr|F5H6D8|F5H6D8_HUMAN,tr|H0YFV6|H0YFV6_HUMAN,tr|B4DTN4|B4DTN4_HUMAN" 4 1676.7886 0.03 119065 16005 3 1676.783419 559.9368 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 5.13 2787.5 - 1.82E+06 - - - -3.0684 - 3.481 0.64 - 505.6 1 1 0 -0.0051 15 0 0 0 3.36E+06 9.69E+07 - - - 8.9287 1 221125_WJC_METTL3_EV_vs_WT_F08.16012.16012.4 2.86E-12 33/138 R.MVVNEGSDGGQSVYHVHLHVLGGR.Q sp|P49773|HINT1_HUMAN 1 2546.2448 1.6 119068 16012 4 2546.242791 637.5685 Adenosine 5'-monophosphoramidase HINT1 OS=Homo sapiens OX=9606 GN=HINT1 PE=1 SV=2 6.21 2788.5 - 2.26E+06 - - - -0.8043 - 5.15 0.72 - 780.7 1 2 0 -0.002 24 0 0 0 9.47E+07 5.91E+07 - - - 6.0184 1 221125_WJC_METTL3_EV_vs_WT_F08.16015.16015.2 1.45E-11 19/28 Q.DDAHPTLVTYADHSK[136.11].L "sp|Q86U44|MTA70_HUMAN,tr|F5H6D8|F5H6D8_HUMAN,tr|H0YFV6|H0YFV6_HUMAN,tr|B4DTN4|B4DTN4_HUMAN" 4 1676.7886 0.02 119070 16015 2 1676.781378 839.4016 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 5.13 2788.8 - 1.33E+06 - - - -4.2856 - 3.14 0.692 - 962.4 1 1 0 -0.0072 15 0 0 0 4.24E+06 2.49E+08 - - - 6.963 1 221125_WJC_METTL3_EV_vs_WT_F08.16017.16017.3 5.50E-07 23/64 K.K[136.11]YFLHDDR[166.11]DDGVDYWAK[136.11].R "sp|Q9NYF8|BCLF1_HUMAN,tr|H0YF14|H0YF14_HUMAN" 2 2168.0173 0.05 119072 16017 3 2168.01556 723.6797 Bcl-2-associated transcription factor 1 OS=Homo sapiens OX=9606 GN=BCLAF1 PE=1 SV=2 4.66 2789 - 1.94E+06 - - - -0.8206 - 3.992 0.608 - 620.4 1 2 1 -0.0018 17 0 0 0 4.94E+06 9.51E+07 - - - 8.8152 0.9998 221125_WJC_METTL3_EV_vs_WT_F08.16024.16024.4 0.00114 14/108 R.VIHLSNLPHSGYSDSAVLK.L "sp|P43243|MATR3_HUMAN,tr|B3KM87|B3KM87_HUMAN,tr|A8MXP9|A8MXP9_HUMAN,tr|D6RBK5|D6RBK5_HUMAN,tr|A0A0R4J2E8|A0A0R4J2E8_HUMAN,tr|H0Y8T4|H0Y8T4_HUMAN,tr|D6REM6|D6REM6_HUMAN" 7 2036.0691 1.31 119074 16024 4 2036.066748 510.0245 Matrin-3 OS=Homo sapiens OX=9606 GN=MATR3 PE=1 SV=2 6.89 2789.9 - 3.83E+06 - - - -1.1503 - 2.632 0.374 - 183.3 1 2 0 -0.0023 19 0 0 0 4.29E+08 3.26E+08 - - - 2.808 1 221125_WJC_METTL3_EV_vs_WT_F08.16026.16026.3 7.79E-07 14/72 R.VIHLSNLPHSGYSDSAVLK[136.11].L "sp|P43243|MATR3_HUMAN,tr|B3KM87|B3KM87_HUMAN,tr|A8MXP9|A8MXP9_HUMAN,tr|D6RBK5|D6RBK5_HUMAN,tr|A0A0R4J2E8|A0A0R4J2E8_HUMAN,tr|H0Y8T4|H0Y8T4_HUMAN,tr|D6REM6|D6REM6_HUMAN" 7 2044.0833 1.26 119075 16026 3 2044.081 682.3684 Matrin-3 OS=Homo sapiens OX=9606 GN=MATR3 PE=1 SV=2 6.89 2790.1 - 1.55E+06 - - - -1.1203 - 2.629 0.495 - 219.8 1 2 0 -0.0023 19 0 0 0 1.93E+08 1.53E+08 - - - 6.4329 1 221125_WJC_METTL3_EV_vs_WT_F08.16030.16030.4 7.53E-08 22/96 R.RAPEEELPPLDPEEIRK.R "sp|Q8IY67|RAVR1_HUMAN,tr|K7EKR9|K7EKR9_HUMAN,tr|E9PAU2|E9PAU2_HUMAN,tr|A0A087WZ13|A0A087WZ13_HUMAN" 4 2017.048 0.16 119077 16030 4 2017.044916 505.2693 Ribonucleoprotein PTB-binding 1 OS=Homo sapiens OX=9606 GN=RAVER1 PE=1 SV=1 4.42 2790.7 - 1.33E+06 - - - -1.5389 - 3.354 0.57 - 394.1 1 2 0 -0.0031 17 0 0 0 6.48E+07 4.10E+08 - - - 4.6066 0.9785 221125_WJC_METTL3_EV_vs_WT_F08.16032.16032.3 0.000234 13/60 L.QDDAHPTLVTYADHSK[136.11].L "sp|Q86U44|MTA70_HUMAN,tr|F5H6D8|F5H6D8_HUMAN,tr|H0YFV6|H0YFV6_HUMAN,tr|B4DTN4|B4DTN4_HUMAN" 4 1804.8471 0.02 119078 16032 3 1804.840941 602.623 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 5.13 2790.9 - 1.14E+07 - - - -3.4357 - 2.225 0.498 - 193.3 1 1 0 -0.0062 16 0 0 0 6.73E+06 4.09E+08 - - - 6.1426 1 221125_WJC_METTL3_EV_vs_WT_F08.16034.16034.3 1.06E-09 27/72 R.VIHLSNLPHSGYSDSAVLK.L "sp|P43243|MATR3_HUMAN,tr|B3KM87|B3KM87_HUMAN,tr|A8MXP9|A8MXP9_HUMAN,tr|D6RBK5|D6RBK5_HUMAN,tr|A0A0R4J2E8|A0A0R4J2E8_HUMAN,tr|H0Y8T4|H0Y8T4_HUMAN,tr|D6REM6|D6REM6_HUMAN" 7 2036.0691 1.26 119079 16034 3 2036.064652 679.697 Matrin-3 OS=Homo sapiens OX=9606 GN=MATR3 PE=1 SV=2 6.89 2791.1 - 3.45E+06 - - - -2.1797 - 4.352 0.601 - 955.4 1 2 0 -0.0044 19 0 0 0 1.93E+08 1.53E+08 - - - 8.8524 0.9998 221125_WJC_METTL3_EV_vs_WT_F08.16036.16036.4 1.86E-11 31/144 R.IQAGEIGEMKDGVPEGAQLQGPVHR.N sp|P16989|YBOX3_HUMAN 1 2615.3126 0.91 119080 16036 4 2615.306581 654.8354 Y-box-binding protein 3 OS=Homo sapiens OX=9606 GN=YBX3 PE=1 SV=4 4.83 2791.3 - 5.44E+06 - - - -2.2953 - 4.424 0.511 - 507.8 1 2 1 -0.006 25 0 0 0 1.50E+08 1.65E+08 - - - 4.1451 1 221125_WJC_METTL3_EV_vs_WT_F08.16037.16037.2 1.44E-11 19/30 L.QDDAHPTLVTYADHSK[136.11].L "sp|Q86U44|MTA70_HUMAN,tr|F5H6D8|F5H6D8_HUMAN,tr|H0YFV6|H0YFV6_HUMAN,tr|B4DTN4|B4DTN4_HUMAN" 4 1804.8471 0.02 119081 16037 2 1804.845121 903.4308 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 5.13 2791.4 - 1.19E+06 - - - -1.1198 - 3.295 0.697 - 847.8 1 1 0 -0.002 16 0 0 0 4.83E+05 2.46E+07 - - - 7.12 1 221125_WJC_METTL3_EV_vs_WT_F08.16046.16046.3 8.95E-07 18/56 R.STSHK[136.11]PDEIYGMIER[166.11].L sp|Q86U44|MTA70_HUMAN 1 1779.8581 0.09 119085 16046 3 1779.854612 594.2933 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 5.42 2792.6 - 1.18E+06 - - - -1.9339 - 3.053 0.516 - 364.6 1 2 0 -0.0034 15 0 0 0 8.28E+06 8.85E+07 - - - 7.2043 1 221125_WJC_METTL3_EV_vs_WT_F08.16057.16057.3 2.23E-07 18/64 R.RAPEEELPPLDPEEIRK.R "sp|Q8IY67|RAVR1_HUMAN,tr|K7EKR9|K7EKR9_HUMAN,tr|E9PAU2|E9PAU2_HUMAN,tr|A0A087WZ13|A0A087WZ13_HUMAN" 4 2017.048 0.12 119091 16057 3 2017.051015 673.3566 Ribonucleoprotein PTB-binding 1 OS=Homo sapiens OX=9606 GN=RAVER1 PE=1 SV=1 4.42 2794 - 861441 - - - 1.4848 - 3.294 0.543 - 358.8 1 2 0 0.003 17 0 0 0 2.10E+07 1.71E+08 - - - 7.6047 1 221125_WJC_METTL3_EV_vs_WT_F08.16061.16061.3 8.98E-08 22/96 R.IQAGEIGEMKDGVPEGAQLQGPVHR.N sp|P16989|YBOX3_HUMAN 1 2615.3126 0.71 119093 16061 3 2615.307277 872.7781 Y-box-binding protein 3 OS=Homo sapiens OX=9606 GN=YBX3 PE=1 SV=4 4.83 2794.5 - 1.40E+06 - - - -2.0292 - 4.28 0.625 - 330.6 1 2 1 -0.0053 25 0 0 0 1.43E+07 2.02E+07 - - - 8.8517 0.9999 221125_WJC_METTL3_EV_vs_WT_F08.16066.16066.4 4.12E-07 28/144 R.IQAGEIGEMK[136.11]DGVPEGAQLQGPVHR[166.11].N sp|P16989|YBOX3_HUMAN 1 2633.3351 0.91 119096 16066 4 2633.331332 659.341 Y-box-binding protein 3 OS=Homo sapiens OX=9606 GN=YBX3 PE=1 SV=4 4.83 2795.1 - 7.06E+06 - - - -1.4134 - 4.423 0.593 - 521.1 1 2 1 -0.0037 25 0 0 0 1.50E+08 1.65E+08 - - - 4.8594 1 221125_WJC_METTL3_EV_vs_WT_F08.16068.16068.3 3.49E-07 27/96 R.IQAGEIGEMK[136.11]DGVPEGAQLQGPVHR[166.11].N sp|P16989|YBOX3_HUMAN 1 2633.3351 0.71 119098 16068 3 2633.332278 878.7856 Y-box-binding protein 3 OS=Homo sapiens OX=9606 GN=YBX3 PE=1 SV=4 4.83 2795.4 - 1.10E+06 - - - -1.0542 - 4.504 0.655 - 741.2 1 2 1 -0.0028 25 0 0 0 1.43E+07 2.02E+07 - - - 9.3042 0.9998 221125_WJC_METTL3_EV_vs_WT_F08.16069.16069.4 0.00309 13/84 R.STSHK[136.11]PDEIYGMIER[166.11].L sp|Q86U44|MTA70_HUMAN 1 1779.8581 0.02 119099 16069 4 1779.856395 445.9718 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 5.42 2795.5 - 704538 - - - -0.9321 - 1.987 0.395 - 92.1 1 2 0 -0.0017 15 0 0 0 2.82E+05 1.81E+07 - - - 2.9093 1 221125_WJC_METTL3_EV_vs_WT_F08.16073.16073.3 2.26E-11 24/76 R.GQQHASVGAAFYVTGVTNQK[136.11].M sp|Q4VCS5|AMOT_HUMAN 1 2070.0374 1.17 119101 16073 3 2070.030159 691.0197 Angiomotin OS=Homo sapiens OX=9606 GN=AMOT PE=1 SV=1 8.6 2796.1 - 820232 - - - -3.499 - 4.107 0.611 - 653 1 2 0 -0.0072 20 0 0 0 1.76E+07 1.50E+07 - - - 8.7773 0.9982 221125_WJC_METTL3_EV_vs_WT_F08.16075.16075.3 1.03E-08 18/80 G.GPK[136.11]PSTASAVPELATDPELEK[136.11].K "sp|Q86U44|MTA70_HUMAN,tr|B4E349|B4E349_HUMAN,tr|F5H6D8|F5H6D8_HUMAN,tr|H0YFV6|H0YFV6_HUMAN,tr|B4DTN4|B4DTN4_HUMAN" 5 2152.1234 0.001 119103 16075 3 2152.122371 718.3818 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 4.41 2796.3 - 874301 - - - -0.4921 - 3.135 0.543 - 294 1 1 0 -0.0011 21 0 0 0 0.00E+00 1.25E+07 - - - 7.333 0.9998 221125_WJC_METTL3_EV_vs_WT_F08.16080.16080.3 2.01E-06 Dec-44 R.TKEIEAIHAILR.S sp|Q15643|TRIPB_HUMAN 1 1392.8089 0.99 119108 16080 3 1392.808497 465.2769 Thyroid receptor-interacting protein 11 OS=Homo sapiens OX=9606 GN=TRIP11 PE=1 SV=3 6.42 2797 - 236783 - - - -0.2886 - 2.079 0.491 - 178.4 1 2 1 -0.0004 12 0 0 0 3.75E+06 3.79E+06 - - - 6.0427 0.9969 221125_WJC_METTL3_EV_vs_WT_F08.16091.16091.3 7.84E-10 22/104 R.GGASQRPLTPNQNQQGQQTDPLVAAAA.V "sp|Q14671|PUM1_HUMAN,tr|Q5T1Z8|Q5T1Z8_HUMAN,tr|H0YDK8|H0YDK8_HUMAN,tr|H0YEH2|H0YEH2_HUMAN,tr|Q5T1Z4|Q5T1Z4_HUMAN,tr|H0YED4|H0YED4_HUMAN,tr|E9PR38|E9PR38_HUMAN" 7 2717.3481 7.24 119115 16091 3 2717.351401 906.79 Pumilio homolog 1 OS=Homo sapiens OX=9606 GN=PUM1 PE=1 SV=3 5.84 2798.4 - 974309 - - - 1.2082 - 3.541 0.479 - 388.9 1 1 0 0.0033 27 0 0 0 2.14E+07 2.96E+06 - - - 6.7884 0.8894 221125_WJC_METTL3_EV_vs_WT_F08.16093.16093.4 0.00695 13/96 R.SLPVPQLVPETEDEK[136.11]K[136.11]R[166.11].F sp|O00154|BACH_HUMAN 1 1990.0945 1.51 119117 16093 4 1991.091119 498.5309 Cytosolic acyl coenzyme A thioester hydrolase OS=Homo sapiens OX=9606 GN=ACOT7 PE=1 SV=3 4.87 2798.7 - 309332 - - - 500.7767 - 2.497 0.396 - 112.5 1 2 1 0.9966 17 0 0 0 6.00E+06 3.98E+06 - - - 2.7144 0.9993 221125_WJC_METTL3_EV_vs_WT_F08.16097.16097.4 3.63E-07 14/96 R.SNAYHFPDEPYKDGYIR.N "sp|Q9NUQ7|UFSP2_HUMAN,tr|D6RGX2|D6RGX2_HUMAN,tr|H0YA18|H0YA18_HUMAN" 3 2070.9436 16.1 119119 16097 4 2070.952653 518.7432 Ufm1-specific protease 2 OS=Homo sapiens OX=9606 GN=UFSP2 PE=1 SV=3 5.36 2799.2 - 613212 - - - 4.3932 - 2.813 0.552 - 122.6 1 2 1 0.0091 17 0 0 0 8.97E+06 5.57E+05 - - - 4.3872 0.9999 221125_WJC_METTL3_EV_vs_WT_F08.16101.16101.4 1.67E-06 15/84 K.K[136.11]NPEVPVNFAEFSK[136.11]K[136.11].C "sp|O15347|HMGB3_HUMAN,tr|E9PES6|E9PES6_HUMAN,tr|E7EQU1|E7EQU1_HUMAN,tr|E7ES08|E7ES08_HUMAN" 4 1756.9574 0.2 119123 16101 4 1756.960679 440.2466 High mobility group protein B3 OS=Homo sapiens OX=9606 GN=HMGB3 PE=1 SV=4 8.5 2799.7 - 434732 - - - 1.8543 - 2.583 0.5 - 207.8 1 2 0 0.0033 15 0 0 0 1.53E+06 7.63E+06 - - - 3.9166 0.8641 221125_WJC_METTL3_EV_vs_WT_F08.16102.16102.3 0.00825 8/104 R.GGASQR[166.11]PLTPNQNQQGQQTDPLVAAAA.V "sp|Q14671|PUM1_HUMAN,tr|Q5T1Z8|Q5T1Z8_HUMAN,tr|H0YDK8|H0YDK8_HUMAN,tr|H0YEH2|H0YEH2_HUMAN,tr|Q5T1Z4|Q5T1Z4_HUMAN,tr|H0YED4|H0YED4_HUMAN,tr|E9PR38|E9PR38_HUMAN" 7 2727.3564 8.21 119124 16102 3 2727.360256 910.1261 Pumilio homolog 1 OS=Homo sapiens OX=9606 GN=PUM1 PE=1 SV=3 5.84 2799.8 - 272221 - - - 1.4182 - 1.485 0.341 - 32.7 1 1 0 0.0039 27 0 0 0 2.43E+07 2.96E+06 - - - 3.2504 1 221125_WJC_METTL3_EV_vs_WT_F08.16108.16108.4 1.20E-07 14/108 R.GLLQDDAHPTLVTYADHSK[136.11].L "sp|Q86U44|MTA70_HUMAN,tr|F5H6D8|F5H6D8_HUMAN,tr|H0YFV6|H0YFV6_HUMAN,tr|B4DTN4|B4DTN4_HUMAN" 4 2088.0367 0.03 119128 16108 4 2088.040713 523.0165 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 5.13 2800.5 - 1.87E+07 - - - 1.9061 - 2.819 0.58 - 162.8 1 2 0 0.004 19 0 0 0 6.79E+08 2.42E+10 - - - 4.6238 1 221125_WJC_METTL3_EV_vs_WT_F08.16109.16109.3 1.01E-12 26/76 R.GQQHASVGAAFYVTGVTNQK.M sp|Q4VCS5|AMOT_HUMAN 1 2062.0232 1.17 119129 16109 3 2062.026403 688.3483 Angiomotin OS=Homo sapiens OX=9606 GN=AMOT PE=1 SV=1 8.6 2800.6 - 841354 - - - 1.5524 - 4.313 0.635 - 994.4 1 2 0 0.0032 20 0 0 0 1.76E+07 1.50E+07 - - - 9.1647 0.9997 221125_WJC_METTL3_EV_vs_WT_F08.16116.16116.3 8.39E-05 9/100 K.GPPDFSSDEER[166.11]EPTPVLGSGAAAAGR[166.11].S "sp|P42166|LAP2A_HUMAN,sp|P42167|LAP2B_HUMAN,tr|G5E972|G5E972_HUMAN" 3 2589.221 3.53 119136 16116 3 2589.223256 864.0809 "Lamina-associated polypeptide 2, isoform alpha OS=Homo sapiens OX=9606 GN=TMPO PE=1 SV=2" 4.18 2801.5 - 130244 - - - 0.8659 - 1.897 0.512 - 44.1 1 2 1 0.0022 26 0 0 0 9.55E+06 2.70E+06 - - - 5.7207 1 221125_WJC_METTL3_EV_vs_WT_F08.16119.16119.3 1.44E-09 22/72 R.GLLQDDAHPTLVTYADHSK[136.11].L "sp|Q86U44|MTA70_HUMAN,tr|F5H6D8|F5H6D8_HUMAN,tr|H0YFV6|H0YFV6_HUMAN,tr|B4DTN4|B4DTN4_HUMAN" 4 2088.0367 0.04 119137 16119 3 2088.042001 697.0195 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 5.13 2801.9 - 2.48E+06 - - - 2.5229 - 3.542 0.655 - 538.4 1 2 0 0.0053 19 0 0 0 7.34E+05 1.78E+07 - - - 8.9482 1 221125_WJC_METTL3_EV_vs_WT_F08.16120.16120.3 6.03E-12 34/96 T.GSSAQEEASGVALGEAPDHSYESLR.V "sp|Q13011|ECH1_HUMAN,tr|M0QYT0|M0QYT0_HUMAN,tr|M0QZW4|M0QZW4_HUMAN,tr|M0R248|M0R248_HUMAN" 4 2546.1521 5.87 119138 16120 3 2546.159778 849.7246 "Delta(3,5)-Delta(2,4)-dienoyl-CoA isomerase, mitochondrial OS=Homo sapiens OX=9606 GN=ECH1 PE=1 SV=2" 4.25 2802 - 868716 - - - 3.014 - 6.133 0.645 - 1464.9 1 1 0 0.0077 25 0 0 0 1.21E+07 2.06E+06 - - - 9.9016 0.9999 221125_WJC_METTL3_EV_vs_WT_F08.16123.16123.3 5.91E-07 15/80 R.EASRPPEEPSAPSPTLPAQFK.Q "sp|Q9H3P2|NELFA_HUMAN,tr|H0Y3X6|H0Y3X6_HUMAN,tr|A0A0C4DFX9|A0A0C4DFX9_HUMAN" 3 2235.1172 0.97 119141 16123 3 2235.123078 746.0463 Negative elongation factor A OS=Homo sapiens OX=9606 GN=NELFA PE=1 SV=3 4.79 2802.4 - 321879 - - - 2.6468 - 2.714 0.566 - 191.7 1 2 0 0.0059 21 0 0 0 2.73E+06 2.82E+06 - - - 7.2424 0.8019 221125_WJC_METTL3_EV_vs_WT_F08.16125.16125.3 0.098 Sep-56 K.DVDAAYMNKVELQAK.A "sp|P48668|K2C6C_HUMAN,sp|P04259|K2C6B_HUMAN,sp|Q14CN4|K2C72_HUMAN,sp|P02538|K2C6A_HUMAN" 4 1693.8345 4.2 119143 16125 3 1693.842555 565.6188 "Keratin, type II cytoskeletal 6C OS=Homo sapiens OX=9606 GN=KRT6C PE=1 SV=3" 4.56 2802.7 - 217854 - - - 4.7425 - 1.594 0.237 - 51.3 1 2 1 0.008 15 0 0 0 2.70E+06 6.44E+05 - - - 2.3967 1 221125_WJC_METTL3_EV_vs_WT_F08.16136.16136.3 8.61E-07 17/84 K.TLTDGVLDINHEQENTPSTSGK[136.11].R "sp|Q13136|LIPA1_HUMAN,tr|E9PJZ7|E9PJZ7_HUMAN,tr|A0A2R8Y7R9|A0A2R8Y7R9_HUMAN" 3 2363.1332 0.89 119152 16136 3 2363.138447 788.7183 Liprin-alpha-1 OS=Homo sapiens OX=9606 GN=PPFIA1 PE=1 SV=1 4.31 2804.1 - 539501 - - - 2.2149 - 3.132 0.575 - 110.9 1 2 0 0.0052 22 0 0 0 5.75E+06 6.45E+06 - - - 7.6559 1 221125_WJC_METTL3_EV_vs_WT_F08.16138.16138.3 1.94E-10 20/84 R.VTELFMDNKNELDQC[160.03]KSDLQNK.T "sp|P52732|KIF11_HUMAN,tr|A0A7I2YQY4|A0A7I2YQY4_HUMAN,tr|A0A7I2V3A9|A0A7I2V3A9_HUMAN,tr|A0A7I2V3V3|A0A7I2V3V3_HUMAN" 4 2668.2473 10.87 119154 16138 3 2668.255287 890.423 Kinesin-like protein KIF11 OS=Homo sapiens OX=9606 GN=KIF11 PE=1 SV=2 4.44 2804.3 - 452702 - - - 3.0057 - 3.969 0.674 - 390.8 1 2 2 0.008 22 0 0 0 7.95E+06 7.31E+05 - - - 9.3204 0.994 221125_WJC_METTL3_EV_vs_WT_F08.16141.16141.4 0.00931 7/114 R.EAIVNSC[160.03]VFVHQTLHQANAR.L "sp|Q14204|DYHC1_HUMAN,tr|A0A7P0T8N2|A0A7P0T8N2_HUMAN,tr|A0A7P0T9C4|A0A7P0T9C4_HUMAN,tr|A0A7P0TBJ7|A0A7P0TBJ7_HUMAN,tr|A0A7P0T9K2|A0A7P0T9K2_HUMAN,tr|A0A2R8Y706|A0A2R8Y706_HUMAN,tr|A0A7P0T916|A0A7P0T916_HUMAN,tr|A0A7P0TB75|A0A7P0TB75_HUMAN,tr|A0A7P0T8W5|A0A7P0T8W5_HUMAN,tr|A0A7P0TAF3|A0A7P0TAF3_HUMAN,tr|A0A7P0T9F1|A0A7P0T9F1_HUMAN,tr|A0A7P0TAW9|A0A7P0TAW9_HUMAN,tr|A0A7P0TA13|A0A7P0TA13_HUMAN,tr|A0A7P0T7V5|A0A7P0T7V5_HUMAN,tr|A0A7P0T9R4|A0A7P0T9R4_HUMAN,tr|A0A2R8Y5T0|A0A2R8Y5T0_HUMAN,tr|A0A2R8YFZ7|A0A2R8YFZ7_HUMAN,tr|A0A7P0T825|A0A7P0T825_HUMAN,tr|A0A2R8Y6H2|A0A2R8Y6H2_HUMAN,tr|A0A7P0TAM4|A0A7P0TAM4_HUMAN" 20 2293.1386 0.72 119157 16141 4 2293.149147 574.2919 Cytoplasmic dynein 1 heavy chain 1 OS=Homo sapiens OX=9606 GN=DYNC1H1 PE=1 SV=5 7 2804.7 - 184074 - - - 4.6068 - 2.036 0.324 - 29.2 1 2 0 0.0106 20 0 0 0 3.59E+06 5.00E+06 - - - 2.2809 0.9739 221125_WJC_METTL3_EV_vs_WT_F08.16143.16143.3 0.0416 Apr-96 R.TPQTVAGYTIPPGHQVC[160.03]VSPTVNQR.L sp|Q16850|CP51A_HUMAN 1 2706.3548 0.14 119159 16143 3 2706.36871 903.1255 Lanosterol 14-alpha demethylase OS=Homo sapiens OX=9606 GN=CYP51A1 PE=1 SV=4 7.92 2805 - 155513 - - - 5.1457 - 1.456 0.376 - 5.4 15 2 0 0.0139 25 0 0 0 1.09E+06 7.83E+06 - - - 3.0482 0.9997 221125_WJC_METTL3_EV_vs_WT_F08.16146.16146.3 5.28E-08 16/80 R.EASR[166.11]PPEEPSAPSPTLPAQFK[136.11].Q "sp|Q9H3P2|NELFA_HUMAN,tr|H0Y3X6|H0Y3X6_HUMAN,tr|A0A0C4DFX9|A0A0C4DFX9_HUMAN" 3 2253.1396 0.64 119161 16146 3 2253.150724 752.0538 Negative elongation factor A OS=Homo sapiens OX=9606 GN=NELFA PE=1 SV=3 4.79 2805.3 - 416038 - - - 4.9229 - 2.958 0.526 - 222.7 1 2 0 0.0111 21 0 0 0 9.04E+06 1.40E+07 - - - 7.0014 0.9983 221125_WJC_METTL3_EV_vs_WT_F08.16147.16147.3 0.00022 18/100 K.GPPDFSSDEEREPTPVLGSGAAAAGR.S "sp|P42166|LAP2A_HUMAN,sp|P42167|LAP2B_HUMAN,tr|G5E972|G5E972_HUMAN" 3 2569.2045 4.07 119162 16147 3 2569.215365 857.4088 "Lamina-associated polypeptide 2, isoform alpha OS=Homo sapiens OX=9606 GN=TMPO PE=1 SV=2" 4.18 2805.4 - 232879 - - - 4.2391 - 2.551 0.493 - 72.6 1 2 1 0.0109 26 0 0 0 1.36E+07 3.34E+06 - - - 6.188 1 221125_WJC_METTL3_EV_vs_WT_F08.16149.16149.3 1.04E-15 24/96 K.QGSLINSLKPSGPTPASGQLSSGDK.A "sp|P35658|NU214_HUMAN,tr|A0A0A0MSW3|A0A0A0MSW3_HUMAN,tr|A0A494C1F2|A0A494C1F2_HUMAN,tr|A0A494C104|A0A494C104_HUMAN,tr|H0Y837|H0Y837_HUMAN" 5 2425.2449 2.18 119164 16149 3 2425.24936 809.4222 Nuclear pore complex protein Nup214 OS=Homo sapiens OX=9606 GN=NUP214 PE=1 SV=2 8.59 2805.7 - 611916 - - - 1.8464 - 4.471 0.697 - 658.5 1 2 0 0.0045 25 0 0 0 5.02E+08 2.31E+08 - - - 9.7551 1 221125_WJC_METTL3_EV_vs_WT_F08.16150.16150.3 1.01E-12 16/56 R.HSEYNPQHSLLAQFR.N sp|Q15797|SMAD1_HUMAN 1 1825.886 1.93 119165 16150 3 1825.890728 609.6359 Mothers against decapentaplegic homolog 1 OS=Homo sapiens OX=9606 GN=SMAD1 PE=1 SV=1 6.92 2805.8 - 524630 - - - 2.6004 - 3.229 0.663 - 329.6 1 2 0 0.0047 15 0 0 0 3.29E+07 1.70E+07 - - - 8.9891 1 221125_WJC_METTL3_EV_vs_WT_F08.16152.16152.3 4.06E-06 27/100 L.TGSSAQEEASGVALGEAPDHSYESLR.V "sp|Q13011|ECH1_HUMAN,tr|M0QYT0|M0QYT0_HUMAN,tr|M0QZW4|M0QZW4_HUMAN,tr|M0R248|M0R248_HUMAN" 4 2647.1998 2.23 119167 16152 3 2647.200947 883.4072 "Delta(3,5)-Delta(2,4)-dienoyl-CoA isomerase, mitochondrial OS=Homo sapiens OX=9606 GN=ECH1 PE=1 SV=2" 4.25 2806.1 - 475817 - - - 0.4401 - 5.642 0.658 - 722.4 1 1 0 0.0012 26 0 0 0 3.27E+07 1.47E+07 - - - 9.8564 0.906 221125_WJC_METTL3_EV_vs_WT_F08.16153.16153.3 0.0666 13/88 T.SGGPK[136.11]PSTASAVPELATDPELEK[136.11].K "sp|Q86U44|MTA70_HUMAN,tr|B4E349|B4E349_HUMAN,tr|F5H6D8|F5H6D8_HUMAN,tr|H0YFV6|H0YFV6_HUMAN,tr|B4DTN4|B4DTN4_HUMAN" 5 2296.1769 0.001 119168 16153 3 2296.187201 766.3996 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 4.41 2806.2 - 244937 - - - 4.4766 - 2.367 0.428 - 113 1 1 0 0.0103 23 0 0 0 0.00E+00 1.88E+07 - - - 5.3302 0.999 221125_WJC_METTL3_EV_vs_WT_F08.16158.16158.4 8.19E-06 18/126 R.VTELFMDNK[136.11]NELDQC[160.03]K[136.11]SDLQNK[136.11].T "sp|P52732|KIF11_HUMAN,tr|A0A7I2YQY4|A0A7I2YQY4_HUMAN,tr|A0A7I2V3A9|A0A7I2V3A9_HUMAN,tr|A0A7I2V3V3|A0A7I2V3V3_HUMAN" 4 2692.2899 4.83 119171 16158 4 2692.295276 674.0797 Kinesin-like protein KIF11 OS=Homo sapiens OX=9606 GN=KIF11 PE=1 SV=2 4.44 2806.9 - 478508 - - - 2.0091 - 2.989 0.384 - 173.2 1 2 2 0.0054 22 0 0 0 4.14E+07 8.59E+06 - - - 2.9251 1 221125_WJC_METTL3_EV_vs_WT_F08.16160.16160.3 4.62E-10 20/60 K.KQC[160.03]ANLQAAIADAEQR.G "sp|P04259|K2C6B_HUMAN,sp|P02538|K2C6A_HUMAN" 2 1785.8792 105.76 119173 16160 3 1785.881448 596.3003 "Keratin, type II cytoskeletal 6B OS=Homo sapiens OX=9606 GN=KRT6B PE=1 SV=5" 6.06 2807.1 - 2.20E+06 - - - 1.2694 - 4.219 0.598 - 642.9 1 2 0 0.0023 16 0 0 0 6.75E+08 6.39E+06 - - - 8.9003 0.9658 221125_WJC_METTL3_EV_vs_WT_F08.16166.16166.4 0.0443 Nov-96 K.KYFLHDDRDDGVDYWAK.R "sp|Q9NYF8|BCLF1_HUMAN,tr|H0YF14|H0YF14_HUMAN" 2 2141.9807 1.9 119177 16166 4 2141.984289 536.5024 Bcl-2-associated transcription factor 1 OS=Homo sapiens OX=9606 GN=BCLAF1 PE=1 SV=2 4.66 2808 - 851596 - - - 1.69 - 1.696 0.218 - 36 1 2 1 0.0036 17 0 0 0 1.10E+08 5.78E+07 - - - 1.3059 1 221125_WJC_METTL3_EV_vs_WT_F08.16169.16169.3 9.36E-10 28/100 L.TGSSAQEEASGVALGEAPDHSYESLR[166.11].V "sp|Q13011|ECH1_HUMAN,tr|M0QYT0|M0QYT0_HUMAN,tr|M0QZW4|M0QZW4_HUMAN,tr|M0R248|M0R248_HUMAN" 4 2657.2081 2.23 119180 16169 3 2657.20214 886.7433 "Delta(3,5)-Delta(2,4)-dienoyl-CoA isomerase, mitochondrial OS=Homo sapiens OX=9606 GN=ECH1 PE=1 SV=2" 4.25 2808.3 - 801178 - - - -2.2249 - 5.138 0.672 - 760.6 1 1 0 -0.0059 26 0 0 0 3.27E+07 1.47E+07 - - - 9.7959 0.9993 221125_WJC_METTL3_EV_vs_WT_F08.16172.16172.3 9.37E-05 Dec-56 R.GPSLNPVLDYDHGSR[166.11].S "sp|P43243|MATR3_HUMAN,tr|A8MXP9|A8MXP9_HUMAN,tr|D6R991|D6R991_HUMAN,tr|A0A0R4J2E8|A0A0R4J2E8_HUMAN,tr|D6REM6|D6REM6_HUMAN" 5 1635.7881 1.51 119183 16172 3 1635.79601 546.27 Matrin-3 OS=Homo sapiens OX=9606 GN=MATR3 PE=1 SV=2 5.21 2808.7 - 315242 - - - 4.8637 - 2.765 0.431 - 229.7 1 2 0 0.008 15 0 0 0 2.21E+07 1.46E+07 - - - 5.9969 1 221125_WJC_METTL3_EV_vs_WT_F08.16176.16176.3 1.57E-08 23/52 K.KQELEEIC[160.03]HDLEAR.V sp|P35579|MYH9_HUMAN 1 1768.8414 0.28 119185 16176 3 1768.841084 590.6211 Myosin-9 OS=Homo sapiens OX=9606 GN=MYH9 PE=1 SV=4 4.57 2809.2 - 719074 - - - -0.1775 - 4.386 0.603 - 1048.6 1 2 0 -0.0003 14 0 0 0 1.41E+08 5.04E+08 - - - 9.1917 1 221125_WJC_METTL3_EV_vs_WT_F08.16179.16179.3 0.00029 15/68 R.NLTHNPPSDFSFQNMNSK.R sp|Q9Y2H1|ST38L_HUMAN 1 2076.9323 4.04 119188 16179 3 2076.933086 693.3181 Serine\threonine-protein kinase 38-like OS=Homo sapiens OX=9606 GN=STK38L PE=1 SV=3 6.74 2809.6 - 888938 - - - 0.3601 - 3.076 0.469 - 343.5 1 2 0 0.0007 18 0 0 0 3.40E+07 8.40E+06 - - - 6.5666 0.9979 221125_WJC_METTL3_EV_vs_WT_F08.16186.16186.4 0.00211 Dec-96 R.SLPVPQLVPETEDEKKR.F sp|O00154|BACH_HUMAN 1 1964.0579 1.47 119190 16186 4 1964.054633 492.0217 Cytosolic acyl coenzyme A thioester hydrolase OS=Homo sapiens OX=9606 GN=ACOT7 PE=1 SV=3 4.87 2810.7 - 249068 - - - -1.641 - 2.261 0.331 - 97.2 1 2 1 -0.0032 17 0 0 0 7.80E+06 5.31E+06 - - - 2.3894 1 221125_WJC_METTL3_EV_vs_WT_F08.16187.16187.4 3.11E-06 13/78 K.KQELEEIC[160.03]HDLEAR.V sp|P35579|MYH9_HUMAN 1 1768.8414 0.93 119191 16187 4 1768.840557 443.2176 Myosin-9 OS=Homo sapiens OX=9606 GN=MYH9 PE=1 SV=4 4.57 2810.8 - 444985 - - - -0.4755 - 2.729 0.527 - 129.3 1 2 0 -0.0008 14 0 0 0 4.58E+07 4.91E+07 - - - 4.1782 0.9998 221125_WJC_METTL3_EV_vs_WT_F08.16192.16192.3 1.88E-06 13/64 K.KQEETAVLEEDSADWEK.E sp|Q96A49|SYAP1_HUMAN 1 2005.9116 1.81 119194 16192 3 2005.920392 669.6445 Synapse-associated protein 1 OS=Homo sapiens OX=9606 GN=SYAP1 PE=1 SV=1 4 2811.5 - 603187 - - - 4.3601 - 3.161 0.527 - 253.4 1 2 0 0.0087 17 0 0 0 1.42E+07 7.84E+06 - - - 7.3206 1 221125_WJC_METTL3_EV_vs_WT_F08.16197.16197.3 4.16E-06 14/92 K.TQVEASEESALNHLQNPGDAAEGR.A "sp|Q9Y605|MOFA1_HUMAN,tr|A0A087WTY9|A0A087WTY9_HUMAN" 2 2522.1633 3.32 119196 16197 3 2522.161786 841.7284 MORF4 family-associated protein 1 OS=Homo sapiens OX=9606 GN=MRFAP1 PE=1 SV=1 4.25 2812.2 - 562799 - - - -0.6149 - 2.923 0.474 - 66.7 1 2 0 -0.0016 24 0 0 0 3.88E+08 1.17E+08 - - - 6.3154 1 221125_WJC_METTL3_EV_vs_WT_F08.16198.16198.2 2.39E-11 20/30 K.KQC[160.03]ANLQAAIADAEQR.G "sp|P04259|K2C6B_HUMAN,sp|P02538|K2C6A_HUMAN" 2 1785.8792 999 119197 16198 2 1785.876676 893.9469 "Keratin, type II cytoskeletal 6B OS=Homo sapiens OX=9606 GN=KRT6B PE=1 SV=5" 6.06 2812.3 - 476614 - - - -1.4027 - 3.761 0.712 - 1065 1 2 0 -0.0025 16 0 0 0 2.44E+07 0.00E+00 - - - 7.5558 1 221125_WJC_METTL3_EV_vs_WT_F08.16204.16204.4 1.16E-06 18/78 K.K[136.11]QELEEIC[160.03]HDLEAR[166.11].V sp|P35579|MYH9_HUMAN 1 1786.8639 0.93 119200 16204 4 1786.865451 447.7232 Myosin-9 OS=Homo sapiens OX=9606 GN=MYH9 PE=1 SV=4 4.57 2813 - 496289 - - - 0.8859 - 3.306 0.492 - 503.9 1 2 0 0.0016 14 0 0 0 4.58E+07 4.91E+07 - - - 3.9431 1 221125_WJC_METTL3_EV_vs_WT_F08.16206.16206.4 0.000118 12/150 K.TVLSSSLNNHPQTSVPNASALHPSLR[166.11].L sp|Q6UUV7|CRTC3_HUMAN 1 2736.4183 2.19 119202 16206 4 2736.422701 685.1118 CREB-regulated transcription coactivator 3 OS=Homo sapiens OX=9606 GN=CRTC3 PE=1 SV=2 9.47 2813.3 - 607433 - - - 1.6229 - 2.534 0.51 - 83.3 1 2 0 0.0044 26 0 0 0 6.71E+07 3.06E+07 - - - 3.9571 1 221125_WJC_METTL3_EV_vs_WT_F08.16214.16214.4 6.24E-07 24/150 K.TVLSSSLNNHPQTSVPNASALHPSLR.L sp|Q6UUV7|CRTC3_HUMAN 1 2726.41 2.19 119206 16214 4 2726.407332 682.6098 CREB-regulated transcription coactivator 3 OS=Homo sapiens OX=9606 GN=CRTC3 PE=1 SV=2 9.47 2814.2 - 2.02E+06 - - - -0.9749 - 3.25 0.548 - 285.9 1 2 0 -0.0027 26 0 0 0 6.71E+07 3.06E+07 - - - 4.3668 0.9718 221125_WJC_METTL3_EV_vs_WT_F08.16221.16221.4 0.00403 12/108 K.KAESPVKEEAVAEVVTITK.S "sp|P07197|NFM_HUMAN,tr|E7ESP9|E7ESP9_HUMAN" 2 2027.115 3.21 119211 16221 4 2027.117425 507.786 Neurofilament medium polypeptide OS=Homo sapiens OX=9606 GN=NEFM PE=1 SV=3 4.95 2815.1 - 525499 - - - 1.178 - 2.782 0.223 - 119 2 2 1 0.0024 19 0 0 0 1.45E+07 4.53E+06 - - - 1.283 0.9999 221125_WJC_METTL3_EV_vs_WT_F08.16227.16227.4 0.000127 Dec-84 R.HSEYNPQHSLLAQFR.N sp|Q15797|SMAD1_HUMAN 1 1825.886 1.75 119215 16227 4 1825.887059 457.4788 Mothers against decapentaplegic homolog 1 OS=Homo sapiens OX=9606 GN=SMAD1 PE=1 SV=1 6.92 2815.9 - 496216 - - - 0.5909 - 2.65 0.421 - 150 1 2 0 0.0011 15 0 0 0 1.07E+07 6.10E+06 - - - 3.2388 0.9994 221125_WJC_METTL3_EV_vs_WT_F08.16232.16232.3 0.00275 Aug-36 R.LVNHFVEEFK[136.11].R "sp|P0DMV8|HS71A_HUMAN,sp|P0DMV9|HS71B_HUMAN,tr|V9GZ37|V9GZ37_HUMAN,tr|A0A0G2JIW1|A0A0G2JIW1_HUMAN" 4 1268.6645 0.07 119218 16232 3 1268.663591 423.8954 Heat shock 70 kDa protein 1A OS=Homo sapiens OX=9606 GN=HSPA1A PE=1 SV=1 5.4 2816.4 - 493043 - - - -0.6952 - 1.609 0.34 - 109.3 1 2 0 -0.0009 10 0 0 0 1.69E+06 2.49E+07 - - - 3.7194 1 221125_WJC_METTL3_EV_vs_WT_F08.16237.16237.3 1.27E-13 19/72 K.KAESPVKEEAVAEVVTITK.S "sp|P07197|NFM_HUMAN,tr|E7ESP9|E7ESP9_HUMAN" 2 2027.115 6.81 119221 16237 3 2027.114218 676.7123 Neurofilament medium polypeptide OS=Homo sapiens OX=9606 GN=NEFM PE=1 SV=3 4.95 2817 - 581485 - - - -0.404 - 4.24 0.641 - 555.9 1 2 1 -0.0008 19 0 0 0 1.44E+07 2.11E+06 - - - 9.2353 1 221125_WJC_METTL3_EV_vs_WT_F08.16238.16238.4 8.84E-12 20/138 K.NLEEGHSSTVAAHYNELQEVGLEK.R sp|O43148|MCES_HUMAN 1 2653.262 1.42 119222 16238 4 2653.261487 664.3228 mRNA cap guanine-N7 methyltransferase OS=Homo sapiens OX=9606 GN=RNMT PE=1 SV=1 4.62 2817 - 2.01E+06 - - - -0.1892 - 3.569 0.581 - 152.5 1 2 0 -0.0005 24 0 0 0 1.03E+08 7.23E+07 - - - 4.6912 1 221125_WJC_METTL3_EV_vs_WT_F08.16245.16245.4 5.08E-11 20/138 K.NLEEGHSSTVAAHYNELQEVGLEK[136.11].R sp|O43148|MCES_HUMAN 1 2661.2762 1.42 119227 16245 4 2661.273027 666.3263 mRNA cap guanine-N7 methyltransferase OS=Homo sapiens OX=9606 GN=RNMT PE=1 SV=1 4.62 2817.9 - 3.57E+06 - - - -1.1882 - 3.882 0.637 - 196 1 2 0 -0.0032 24 0 0 0 1.03E+08 7.23E+07 - - - 5.2049 1 221125_WJC_METTL3_EV_vs_WT_F08.16246.16246.3 5.79E-11 23/84 K.DHTPSQELALTQSVGGDSSADR[166.11].L "sp|Q86U44|MTA70_HUMAN,tr|H0YFV6|H0YFV6_HUMAN" 2 2280.0494 0.07 119228 16246 3 2281.037048 761.0237 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 4.22 2818 - 1.72E+06 - - - 433.184 - 3.869 0.638 - 494.3 1 2 0 0.9877 22 0 0 0 1.25E+07 1.92E+08 - - - 8.5872 1 221125_WJC_METTL3_EV_vs_WT_F08.16247.16247.3 3.48E-11 18/72 R.DSAWGTSDHSVSQPIMVQR.R "sp|Q14671|PUM1_HUMAN,tr|Q5T1Z8|Q5T1Z8_HUMAN,tr|H0YEH2|H0YEH2_HUMAN,tr|Q5T1Z4|Q5T1Z4_HUMAN" 4 2099.9695 1.92 119229 16247 3 2099.969644 700.9971 Pumilio homolog 1 OS=Homo sapiens OX=9606 GN=PUM1 PE=1 SV=3 5.21 2818.1 - 930631 - - - 0.0914 - 3.236 0.594 - 294.1 1 2 0 0.0002 19 0 0 0 1.71E+07 8.93E+06 - - - 8.0476 1 221125_WJC_METTL3_EV_vs_WT_F08.16251.16251.3 7.49E-10 19/76 K.DQVTAQEIFQDNHEDGPTAK[136.11].K sp|P13010|XRCC5_HUMAN 1 2250.028 0.92 119231 16251 3 2250.021135 751.0166 X-ray repair cross-complementing protein 5 OS=Homo sapiens OX=9606 GN=XRCC5 PE=1 SV=3 4.1 2818.6 - 1.65E+06 - - - -3.0595 - 3.589 0.61 - 278.6 1 2 0 -0.0069 20 0 0 0 1.13E+08 1.22E+08 - - - 8.4391 1 221125_WJC_METTL3_EV_vs_WT_F08.16252.16252.3 1.04E-08 17/88 K.NALPPVLTTVNGQSPPEHSAPAK.V "sp|Q6PKG0|LARP1_HUMAN,tr|A0A0B4J210|A0A0B4J210_HUMAN,tr|H0YBM7|H0YBM7_HUMAN" 3 2324.2125 1.58 119232 16252 3 2324.21188 775.7448 La-related protein 1 OS=Homo sapiens OX=9606 GN=LARP1 PE=1 SV=2 6.75 2818.8 - 853950 - - - -0.2495 - 3.384 0.643 - 305 1 2 0 -0.0006 23 0 0 0 3.13E+07 1.99E+07 - - - 8.5685 1 221125_WJC_METTL3_EV_vs_WT_F08.16253.16253.3 3.30E-07 22/120 R.SLGSVQAPSYGAR[166.11]PVSSAASVYAGAGGSGSR[166.11].L "sp|P05783|K1C18_HUMAN,tr|F8VZY9|F8VZY9_HUMAN" 2 2873.4171 1.93 119233 16253 3 2873.413868 958.813 "Keratin, type I cytoskeletal 18 OS=Homo sapiens OX=9606 GN=KRT18 PE=1 SV=2" 9.98 2818.9 - 707613 - - - -1.1206 - 3.637 0.58 - 259.3 1 2 0 -0.0032 31 0 0 0 2.68E+07 1.39E+07 - - - 7.976 1 221125_WJC_METTL3_EV_vs_WT_F08.16257.16257.3 2.09E-09 30/92 K.NLEEGHSSTVAAHYNELQEVGLEK.R sp|O43148|MCES_HUMAN 1 2653.262 1.54 119235 16257 3 2653.259554 885.4279 mRNA cap guanine-N7 methyltransferase OS=Homo sapiens OX=9606 GN=RNMT PE=1 SV=1 4.62 2819.4 - 1.26E+06 - - - -0.9177 - 5.579 0.705 - 888.2 1 2 0 -0.0024 24 0 0 0 2.43E+07 1.58E+07 - - - 10.3919 1 221125_WJC_METTL3_EV_vs_WT_F08.16258.16258.3 2.46E-11 28/120 R.SLGSVQAPSYGARPVSSAASVYAGAGGSGSR.L "sp|P05783|K1C18_HUMAN,tr|F8VZY9|F8VZY9_HUMAN" 2 2853.4005 1.93 119236 16258 3 2853.400594 952.1408 "Keratin, type I cytoskeletal 18 OS=Homo sapiens OX=9606 GN=KRT18 PE=1 SV=2" 9.98 2819.6 - 1.39E+06 - - - 0.0161 - 4.301 0.647 - 405.5 1 2 0 0 31 0 0 0 2.68E+07 1.39E+07 - - - 9.1097 1 221125_WJC_METTL3_EV_vs_WT_F08.16260.16260.3 2.01E-10 19/88 K.NALPPVLTTVNGQSPPEHSAPAK[136.11].V "sp|Q6PKG0|LARP1_HUMAN,tr|A0A0B4J210|A0A0B4J210_HUMAN,tr|H0YBM7|H0YBM7_HUMAN" 3 2332.2267 1.57 119238 16260 3 2332.223752 778.4162 La-related protein 1 OS=Homo sapiens OX=9606 GN=LARP1 PE=1 SV=2 6.75 2819.8 - 577365 - - - -1.2469 - 3.494 0.622 - 375.5 1 2 0 -0.0029 23 0 0 0 3.08E+07 1.96E+07 - - - 8.4088 1 221125_WJC_METTL3_EV_vs_WT_F08.16261.16261.3 1.70E-09 10/108 K.TLEVVSPSQSVTGSAGHTPYYQSPTDEK.S sp|P46821|MAP1B_HUMAN 1 2964.3989 2.59 119239 16261 3 2964.399171 989.1402 Microtubule-associated protein 1B OS=Homo sapiens OX=9606 GN=MAP1B PE=1 SV=2 4.65 2819.9 - 260164 - - - 0.0995 - 2.588 0.626 - 75.8 1 2 0 0.0003 28 0 0 0 4.78E+06 1.85E+06 - - - 7.7068 0.9988 221125_WJC_METTL3_EV_vs_WT_F08.16266.16266.4 0.00377 11/144 K.QGSLINSLKPSGPTPASGQLSSGDK.A "sp|P35658|NU214_HUMAN,tr|A0A0A0MSW3|A0A0A0MSW3_HUMAN,tr|A0A494C1F2|A0A494C1F2_HUMAN,tr|A0A494C104|A0A494C104_HUMAN,tr|H0Y837|H0Y837_HUMAN" 5 2425.2449 4.76 119242 16266 4 2425.246643 607.3185 Nuclear pore complex protein Nup214 OS=Homo sapiens OX=9606 GN=NUP214 PE=1 SV=2 8.59 2820.5 - 749381 - - - 0.7261 - 2.344 0.286 - 81.3 1 2 0 0.0018 25 0 0 0 1.90E+07 3.99E+06 - - - 1.9859 0.992 221125_WJC_METTL3_EV_vs_WT_F08.16267.16267.4 0.00854 11/108 K.K[136.11]AESPVK[136.11]EEAVAEVVTITK[136.11].S "sp|P07197|NFM_HUMAN,tr|E7ESP9|E7ESP9_HUMAN" 2 2051.1576 3.21 119243 16267 4 2051.152919 513.7967 Neurofilament medium polypeptide OS=Homo sapiens OX=9606 GN=NEFM PE=1 SV=3 4.95 2820.7 - 263939 - - - -2.3002 - 2.376 0.286 - 106.6 1 2 1 -0.0047 19 0 0 0 1.45E+07 4.53E+06 - - - 2.0068 0.9998 221125_WJC_METTL3_EV_vs_WT_F08.16271.16271.4 4.89E-05 22/108 R.EDLQLDKPASGVKEEWYAR.L "sp|P78347|GTF2I_HUMAN,tr|A0A494C0Q7|A0A494C0Q7_HUMAN,tr|A0A494C1K3|A0A494C1K3_HUMAN" 3 2233.1015 1.71 119245 16271 4 2233.102677 559.2827 General transcription factor II-I OS=Homo sapiens OX=9606 GN=GTF2I PE=1 SV=2 4.51 2821.2 - 893823 - - - 0.5217 - 3.761 0.465 - 377.8 1 2 1 0.0012 19 0 0 0 2.50E+07 1.46E+07 - - - 3.7212 1 221125_WJC_METTL3_EV_vs_WT_F08.16281.16281.3 4.50E-11 27/92 K.NLEEGHSSTVAAHYNELQEVGLEK[136.11].R sp|O43148|MCES_HUMAN 1 2661.2762 1.54 119251 16281 3 2661.278651 888.0993 mRNA cap guanine-N7 methyltransferase OS=Homo sapiens OX=9606 GN=RNMT PE=1 SV=1 4.62 2822.4 - 649210 - - - 0.9251 - 5.118 0.735 - 712.5 1 2 0 0.0025 24 0 0 0 2.43E+07 1.58E+07 - - - 10.5261 0.9809 221125_WJC_METTL3_EV_vs_WT_F08.16282.16282.3 1.24E-05 20/88 L.SSSKGSLGGGFSSGGFSGGSFSR.G "sp|P13645|K1C10_HUMAN,tr|A0A1B0GVI3|A0A1B0GVI3_HUMAN" 2 2095.9559 35.53 119252 16282 3 2095.961152 699.6592 "Keratin, type I cytoskeletal 10 OS=Homo sapiens OX=9606 GN=KRT10 PE=1 SV=6" 11 2822.5 - 814452 - - - 2.501 - 3.458 0.545 - 263.8 1 1 1 0.0052 23 0 0 0 1.09E+07 3.08E+05 - - - 7.5253 1 221125_WJC_METTL3_EV_vs_WT_F08.16283.16283.3 1.44E-08 21/72 R.EDLQLDKPASGVKEEWYAR.L "sp|P78347|GTF2I_HUMAN,tr|A0A494C0Q7|A0A494C0Q7_HUMAN,tr|A0A494C1K3|A0A494C1K3_HUMAN" 3 2233.1015 1.94 119253 16283 3 2233.10542 745.3744 General transcription factor II-I OS=Homo sapiens OX=9606 GN=GTF2I PE=1 SV=2 4.51 2822.6 - 681408 - - - 1.75 - 3.989 0.599 - 576.8 1 2 1 0.0039 19 0 0 0 8.18E+06 4.21E+06 - - - 8.6163 1 221125_WJC_METTL3_EV_vs_WT_F08.16286.16286.4 1.59E-08 16/138 K.TQVEASEESALNHLQNPGDAAEGR.A "sp|Q9Y605|MOFA1_HUMAN,tr|A0A087WTY9|A0A087WTY9_HUMAN" 2 2522.1633 6.03 119254 16286 4 2522.165843 631.5481 MORF4 family-associated protein 1 OS=Homo sapiens OX=9606 GN=MRFAP1 PE=1 SV=1 4.25 2823.1 - 1.02E+06 - - - 0.9936 - 3.175 0.512 - 134.7 1 2 0 0.0025 24 0 0 0 1.83E+07 3.03E+06 - - - 4.0526 0.9996 221125_WJC_METTL3_EV_vs_WT_F08.16292.16292.4 0.00679 9/102 K.ADSGSSLQPLPHHPFNFR[166.11].S "sp|Q9HAZ2|PRD16_HUMAN,tr|D6RDW0|D6RDW0_HUMAN,tr|D6RFY3|D6RFY3_HUMAN,tr|H0YA13|H0YA13_HUMAN" 4 2015.9841 1.34 119260 16292 4 2015.980698 505.0033 Histone-lysine N-methyltransferase PRDM16 OS=Homo sapiens OX=9606 GN=PRDM16 PE=1 SV=3 6.96 2823.8 - 161999 - - - -1.7014 - 1.775 0.354 - 36 1 2 0 -0.0034 18 0 0 0 3.48E+06 2.60E+06 - - - 2.5028 0.9538 221125_WJC_METTL3_EV_vs_WT_F08.16293.16293.4 1.5 Aug-84 K.AADHLK[136.11]PFLDDSTLR[166.11].F sp|O43395|PRPF3_HUMAN 1 1715.8962 2.5 119261 16293 4 1715.89318 429.9813 U4\U6 small nuclear ribonucleoprotein Prp3 OS=Homo sapiens OX=9606 GN=PRPF3 PE=1 SV=2 5.3 2823.9 - 126098 - - - -1.7332 - 1.574 0.152 - 46.2 1 2 0 -0.003 15 0 0 0 3.65E+06 1.46E+06 - - - 0.7105 1 221125_WJC_METTL3_EV_vs_WT_F08.16297.16297.3 8.15E-07 15/56 R.STSHK[136.11]PDEIYGMIER[166.11].L sp|Q86U44|MTA70_HUMAN 1 1779.8581 0.02 119263 16297 3 1779.855662 594.2933 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 5.42 2824.4 - 1.07E+06 - - - -1.3439 - 2.784 0.507 - 309.1 1 2 0 -0.0024 15 0 0 0 8.81E+05 3.65E+07 - - - 6.8636 1 221125_WJC_METTL3_EV_vs_WT_F08.16302.16302.3 4.00E-13 26/108 R.ATAPVPTVGEGYGYGHESELSQASAAAR[166.11].N "sp|Q9BWF3|RBM4_HUMAN,tr|E9PB51|E9PB51_HUMAN" 2 2785.3183 1.53 119268 16302 3 2785.317413 929.4467 RNA-binding protein 4 OS=Homo sapiens OX=9606 GN=RBM4 PE=1 SV=1 4.75 2824.9 - 675643 - - - -0.308 - 4.193 0.724 - 380.5 1 2 0 -0.0009 28 0 0 0 7.36E+07 4.80E+07 - - - 9.9094 1 221125_WJC_METTL3_EV_vs_WT_F08.16303.16303.3 2.86E-09 20/72 R.KQTIDNSQGAYQEAFDISK.K sp|P27348|1433T_HUMAN 1 2142.0229 1 119269 16303 3 2142.023292 715.0149 14-3-3 protein theta OS=Homo sapiens OX=9606 GN=YWHAQ PE=1 SV=1 4.56 2825.1 - 624996 - - - 0.1704 - 4.05 0.652 - 668.9 1 2 0 0.0004 19 0 0 0 5.37E+07 5.35E+07 - - - 9.2454 1 221125_WJC_METTL3_EV_vs_WT_F08.16307.16307.3 4.74E-15 30/108 R.ATAPVPTVGEGYGYGHESELSQASAAAR.N "sp|Q9BWF3|RBM4_HUMAN,tr|E9PB51|E9PB51_HUMAN" 2 2775.31 1.53 119271 16307 3 2775.311097 926.1106 RNA-binding protein 4 OS=Homo sapiens OX=9606 GN=RBM4 PE=1 SV=1 4.75 2825.6 - 2.08E+06 - - - 0.3949 - 5.075 0.747 - 661.7 1 2 0 0.0011 28 0 0 0 7.36E+07 4.80E+07 - - - 10.605 0.9999 221125_WJC_METTL3_EV_vs_WT_F08.16308.16308.4 1.46E-07 22/120 R.EVATNSELVQSGKSEISELRR.T "sp|Q04695|K1C17_HUMAN,sp|P02533|K1C14_HUMAN,tr|F5GWP8|F5GWP8_HUMAN" 3 2331.203 8.74 119272 16308 4 2331.205317 583.808 "Keratin, type I cytoskeletal 17 OS=Homo sapiens OX=9606 GN=KRT17 PE=1 SV=2" 4.95 2825.7 - 1.93E+06 - - - 0.9866 - 3.959 0.533 - 375.4 1 2 1 0.0023 21 0 0 0 2.32E+07 2.65E+06 - - - 4.3196 1 221125_WJC_METTL3_EV_vs_WT_F08.16309.16309.3 9.26E-10 22/72 R.K[136.11]QTIDNSQGAYQEAFDISK[136.11].K sp|P27348|1433T_HUMAN 1 2158.0513 0.98 119273 16309 3 2158.052149 720.3577 14-3-3 protein theta OS=Homo sapiens OX=9606 GN=YWHAQ PE=1 SV=1 4.56 2825.8 - 1.44E+06 - - - 0.3809 - 4.144 0.598 - 819.7 1 2 0 0.0008 19 0 0 0 5.41E+07 5.52E+07 - - - 8.6996 0.9999 221125_WJC_METTL3_EV_vs_WT_F08.16311.16311.4 3.54E-05 16/126 R.EATTDFTVDSR[166.11]PLTQVGGDHIK[136.11].A "sp|O75369|FLNB_HUMAN,tr|E7EN95|E7EN95_HUMAN,tr|A0A804HK76|A0A804HK76_HUMAN,tr|A0A804HL72|A0A804HL72_HUMAN" 4 2404.1989 1.28 119275 16311 4 2404.200416 602.057 Filamin-B OS=Homo sapiens OX=9606 GN=FLNB PE=1 SV=2 4.66 2826 - 480372 - - - 0.6148 - 2.929 0.459 - 158.1 1 2 0 0.0015 22 0 0 0 2.31E+07 1.81E+07 - - - 3.5724 0.9895 221125_WJC_METTL3_EV_vs_WT_F08.16313.16313.3 3.98E-07 18/104 K.SR[166.11]PNASGGAAC[160.03]SGPGPEPAVFC[160.03]EPVVK[136.11].L "sp|Q6L8Q7|PDE12_HUMAN,tr|F6T1Q0|F6T1Q0_HUMAN" 2 2715.2864 2.38 119277 16313 3 2716.273545 906.1027 "2',5'-phosphodiesterase 12 OS=Homo sapiens OX=9606 GN=PDE12 PE=1 SV=2" 5.86 2826.3 - 343007 - - - 363.5547 - 3.443 0.617 - 231.4 1 2 0 0.9872 27 0 0 0 7.45E+06 3.13E+06 - - - 7.9899 0.9995 221125_WJC_METTL3_EV_vs_WT_F08.16319.16319.4 0.00986 14/84 R.STSHK[136.11]PDEIYGMIER[166.11].L sp|Q86U44|MTA70_HUMAN 1 1779.8581 0.01 119282 16319 4 1779.858742 445.9718 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 5.42 2827 - 486558 - - - 0.3865 - 2.305 0.328 - 148.2 1 2 0 0.0007 15 0 0 0 2.39E+05 1.91E+07 - - - 2.3795 0.9998 221125_WJC_METTL3_EV_vs_WT_F08.16323.16323.4 2.27E-06 13/126 R.EATTDFTVDSRPLTQVGGDHIK.A "sp|O75369|FLNB_HUMAN,tr|E7EN95|E7EN95_HUMAN,tr|A0A804HK76|A0A804HK76_HUMAN,tr|A0A804HL72|A0A804HL72_HUMAN" 4 2386.1765 0.88 119285 16323 4 2386.182859 597.5514 Filamin-B OS=Homo sapiens OX=9606 GN=FLNB PE=1 SV=2 4.66 2827.5 - 716120 - - - 2.6783 - 3.006 0.419 - 109.7 1 2 0 0.0064 22 0 0 0 1.48E+07 1.68E+07 - - - 3.2313 1 221125_WJC_METTL3_EV_vs_WT_F08.16326.16326.3 4.00E-10 14/104 K.SRPNASGGAAC[160.03]SGPGPEPAVFC[160.03]EPVVK.L "sp|Q6L8Q7|PDE12_HUMAN,tr|F6T1Q0|F6T1Q0_HUMAN" 2 2697.2639 2.11 119288 16326 3 2697.261239 900.0952 "2',5'-phosphodiesterase 12 OS=Homo sapiens OX=9606 GN=PDE12 PE=1 SV=2" 5.86 2827.9 - 406379 - - - -0.994 - 3.09 0.688 - 99.7 1 2 0 -0.0027 27 0 0 0 6.60E+06 3.13E+06 - - - 8.8053 1 221125_WJC_METTL3_EV_vs_WT_F08.16332.16332.4 1.48E-12 22/162 R.ATAPVPTVGEGYGYGHESELSQASAAAR.N "sp|Q9BWF3|RBM4_HUMAN,tr|E9PB51|E9PB51_HUMAN" 2 2775.31 2.49 119292 16332 4 2775.315464 694.8348 RNA-binding protein 4 OS=Homo sapiens OX=9606 GN=RBM4 PE=1 SV=1 4.75 2828.7 - 1.14E+06 - - - 1.9684 - 3.893 0.643 - 222.8 1 2 0 0.0055 28 0 0 0 1.00E+07 4.02E+06 - - - 5.2432 1 221125_WJC_METTL3_EV_vs_WT_F08.16333.16333.3 2.89E-13 23/76 R.SDQQAQVHQLLTPASAISNK.E "sp|Q8NDV7|TNR6A_HUMAN,tr|H7C269|H7C269_HUMAN" 2 2135.0971 3.84 119293 16333 3 2135.099913 712.7063 Trinucleotide repeat-containing gene 6A protein OS=Homo sapiens OX=9606 GN=TNRC6A PE=1 SV=2 6.46 2828.8 - 976851 - - - 1.3198 - 4.585 0.656 - 494.5 1 2 0 0.0028 20 0 0 0 3.77E+07 9.83E+06 - - - 9.5473 1 221125_WJC_METTL3_EV_vs_WT_F08.16337.16337.4 5.26E-07 16/78 R.HADEFLLDLGHHER[166.11].S "sp|Q9BYC5|FUT8_HUMAN,tr|A0A669KAW1|A0A669KAW1_HUMAN" 2 1697.8149 1.57 119297 16337 4 1697.81494 425.461 "Alpha-(1,6)-fucosyltransferase OS=Homo sapiens OX=9606 GN=FUT8 PE=1 SV=2" 5.21 2829.3 - 261614 - - - 0.0018 - 3.626 0.557 - 285 1 2 0 0 14 0 0 0 5.70E+06 3.63E+06 - - - 4.5429 1 221125_WJC_METTL3_EV_vs_WT_F08.16345.16345.4 1.02E-06 18/78 R.HADEFLLDLGHHER.S "sp|Q9BYC5|FUT8_HUMAN,tr|A0A669KAW1|A0A669KAW1_HUMAN" 2 1687.8067 1.47 119303 16345 4 1687.806425 422.9589 "Alpha-(1,6)-fucosyltransferase OS=Homo sapiens OX=9606 GN=FUT8 PE=1 SV=2" 5.21 2830.4 - 498765 - - - -0.1434 - 3.891 0.568 - 451 1 2 0 -0.0002 14 0 0 0 5.72E+06 3.88E+06 - - - 4.6643 1 221125_WJC_METTL3_EV_vs_WT_F08.16346.16346.3 2.10E-07 Nov-84 R.EATTDFTVDSR[166.11]PLTQVGGDHIK[136.11].A "sp|O75369|FLNB_HUMAN,tr|E7EN95|E7EN95_HUMAN,tr|A0A804HK76|A0A804HK76_HUMAN,tr|A0A804HL72|A0A804HL72_HUMAN" 4 2404.1989 0.25 119304 16346 3 2404.202335 802.4069 Filamin-B OS=Homo sapiens OX=9606 GN=FLNB PE=1 SV=2 4.66 2830.5 - 482203 - - - 1.4129 - 2.527 0.54 - 143.4 1 2 0 0.0034 22 0 0 0 8.19E+05 3.28E+06 - - - 6.7574 0.9902 221125_WJC_METTL3_EV_vs_WT_F08.16347.16347.3 7.43E-08 17/80 S.SKGSLGGGFSSGGFSGGSFSR.G "sp|P13645|K1C10_HUMAN,tr|A0A1B0GVI3|A0A1B0GVI3_HUMAN" 2 1921.8919 83.16 119305 16347 3 1921.893693 641.6379 "Keratin, type I cytoskeletal 10 OS=Homo sapiens OX=9606 GN=KRT10 PE=1 SV=6" 11 2830.6 - 456544 - - - 0.9569 - 3.521 0.501 - 309.3 1 1 1 0.0018 21 0 0 0 4.17E+06 5.01E+04 - - - 7.1429 0.9984 221125_WJC_METTL3_EV_vs_WT_F08.16350.16350.4 0.0152 7/114 R.HIGK[136.11]PLLGGPFSLTTHTGER[166.11].K "sp|O75880|SCO1_HUMAN,tr|J3QL56|J3QL56_HUMAN" 2 2135.1606 1.13 119308 16350 4 2135.166203 534.7974 "Protein SCO1 homolog, mitochondrial OS=Homo sapiens OX=9606 GN=SCO1 PE=1 SV=1" 8.76 2831 - 158204 - - - 2.6045 - 1.266 0.363 - 9.4 2 2 0 0.0056 20 0 0 0 9.31E+06 8.21E+06 - - - 2.2334 0.9948 221125_WJC_METTL3_EV_vs_WT_F08.16354.16354.3 0.00566 Nov-44 K.NKLEGLEDALQK.A "sp|P48668|K2C6C_HUMAN,sp|P04259|K2C6B_HUMAN,sp|P02538|K2C6A_HUMAN" 3 1356.7249 1065.06 119310 16354 3 1356.727466 453.2489 "Keratin, type II cytoskeletal 6C OS=Homo sapiens OX=9606 GN=KRT6C PE=1 SV=3" 4.68 2831.6 - 746684 - - - 1.895 - 2.267 0.255 - 296.5 1 2 1 0.0026 12 0 0 0 1.84E+07 1.73E+04 - - - 3.6509 1 221125_WJC_METTL3_EV_vs_WT_F08.16357.16357.3 1.26E-12 20/72 R.GGHMDDGGYSMNFNMSSSR.G "sp|Q96E39|RMXL1_HUMAN,sp|P38159|RBMX_HUMAN,tr|A0A1B0GUK8|A0A1B0GUK8_HUMAN,tr|H3BT71|H3BT71_HUMAN,tr|H0Y6E7|H0Y6E7_HUMAN" 5 2048.7775 1.36 119313 16357 3 2048.77926 683.9331 "RNA binding motif protein, X-linked-like-1 OS=Homo sapiens OX=9606 GN=RBMXL1 PE=1 SV=1" 5.21 2831.9 - 712641 - - - 0.862 - 4.091 0.702 - 674.3 1 2 0 0.0018 19 0 0 0 5.62E+07 4.13E+07 - - - 9.8272 1 221125_WJC_METTL3_EV_vs_WT_F08.16360.16360.3 4.75E-08 11/104 R.TASISSSPSEGTPTVGSYGC[160.03]TPQSLPK.F sp|Q6PKG0|LARP1_HUMAN 1 2695.2647 1.53 119316 16360 3 2695.264341 899.4288 La-related protein 1 OS=Homo sapiens OX=9606 GN=LARP1 PE=1 SV=2 5.66 2832.4 - 258551 - - - -0.1299 - 2.643 0.569 - 87.1 1 2 0 -0.0003 27 0 0 0 6.37E+06 4.15E+06 - - - 7.1197 1 221125_WJC_METTL3_EV_vs_WT_F08.16364.16364.4 3.09E-10 20/126 K.K[136.11]TFPTVNPTTGEVIGHVAEGDR[166.11].A "sp|P30837|AL1B1_HUMAN,tr|A0A0U1RQK9|A0A0U1RQK9_HUMAN" 2 2342.1985 1.49 119318 16364 4 2342.201759 586.5569 "Aldehyde dehydrogenase X, mitochondrial OS=Homo sapiens OX=9606 GN=ALDH1B1 PE=1 SV=3" 5.45 2832.9 - 237136 - - - 1.3726 - 4.19 0.56 - 351 1 2 0 0.0032 22 0 0 0 4.83E+06 3.25E+06 - - - 4.5681 0.9996 221125_WJC_METTL3_EV_vs_WT_F08.16367.16367.4 1.45E-06 15/102 K.ITNEKGEC[160.03]IVSDFTIGRK.G "sp|P52948|NUP98_HUMAN,tr|A0A3B3ITD8|A0A3B3ITD8_HUMAN" 2 2066.0466 16.64 119321 16367 4 2066.053842 517.5189 Nuclear pore complex protein Nup98-Nup96 OS=Homo sapiens OX=9606 GN=NUP98 PE=1 SV=4 6.17 2833.3 - 404811 - - - 3.4859 - 3.056 0.55 - 159.5 1 2 1 0.0072 18 0 0 0 5.81E+06 3.49E+05 - - - 4.3939 1 221125_WJC_METTL3_EV_vs_WT_F08.16368.16368.3 2.84E-08 11/104 R.TASISSSPSEGTPTVGSYGC[160.03]TPQSLPK[136.11].F sp|Q6PKG0|LARP1_HUMAN 1 2703.2789 1.79 119322 16368 3 2703.277359 902.1002 La-related protein 1 OS=Homo sapiens OX=9606 GN=LARP1 PE=1 SV=2 5.66 2833.4 - 339843 - - - -0.5667 - 2.698 0.575 - 80.4 1 2 0 -0.0015 27 0 0 0 7.42E+06 4.15E+06 - - - 7.2337 0.9998 221125_WJC_METTL3_EV_vs_WT_F08.16369.16369.4 3.82E-09 12/132 R.VVNMNQQSDTADLLGGYK[136.11]PVDHK[136.11].L "sp|Q9NU22|MDN1_HUMAN,tr|Q5T795|Q5T795_HUMAN" 2 2544.2613 0.69 119323 16369 4 2544.27283 637.0726 Midasin OS=Homo sapiens OX=9606 GN=MDN1 PE=1 SV=2 5.3 2833.5 - 336286 - - - 4.5172 - 2.921 0.548 - 89.4 1 2 0 0.0115 23 0 0 0 2.10E+06 3.03E+06 - - - 4.3399 1 221125_WJC_METTL3_EV_vs_WT_F08.16376.16376.3 1.18E-05 14/104 K.ADLIPYQDSPEGPDHSSASSGVPNPPK.A "sp|Q8WUA4|TF3C2_HUMAN,tr|H0Y4Q6|H0Y4Q6_HUMAN,tr|H7C318|H7C318_HUMAN" 3 2761.2831 1.67 119329 16376 3 2761.280068 921.435 General transcription factor 3C polypeptide 2 OS=Homo sapiens OX=9606 GN=GTF3C2 PE=1 SV=2 4.22 2834.5 - 396897 - - - -1.1046 - 2.484 0.492 - 115.1 1 2 0 -0.0031 27 0 0 0 3.64E+06 2.19E+06 - - - 6.1177 0.995 221125_WJC_METTL3_EV_vs_WT_F08.16379.16379.3 5.11E-05 Oct-76 F.GQSPFSQPPAPPHQNTFPPR.S sp|Q96I24|FUBP3_HUMAN 1 2186.0657 999 119332 16379 3 2186.066544 729.6959 Far upstream element-binding protein 3 OS=Homo sapiens OX=9606 GN=FUBP3 PE=1 SV=2 9.76 2834.9 - 247735 - - - 0.3696 - 2.606 0.457 - 69.9 1 1 0 0.0008 20 0 0 0 4.05E+06 0.00E+00 - - - 5.9586 0.9888 221125_WJC_METTL3_EV_vs_WT_F08.16380.16380.4 0.0106 8/132 R.VVNMNQQSDTADLLGGYKPVDHK.L "sp|Q9NU22|MDN1_HUMAN,tr|Q5T795|Q5T795_HUMAN" 2 2528.2329 0.69 119333 16380 4 2528.241194 633.0655 Midasin OS=Homo sapiens OX=9606 GN=MDN1 PE=1 SV=2 5.3 2835 - 242952 - - - 3.2659 - 2.039 0.248 - 37.9 1 2 0 0.0083 23 0 0 0 2.10E+06 3.03E+06 - - - 1.6131 0.9999 221125_WJC_METTL3_EV_vs_WT_F08.16384.16384.3 4.95E-05 11/100 R.LSVGAVSSKPTTPTIATPQTVSVPNK.V sp|Q9HBM6|TAF9B_HUMAN 1 2579.417 1.27 119335 16384 3 2579.421933 860.813 Transcription initiation factor TFIID subunit 9B OS=Homo sapiens OX=9606 GN=TAF9B PE=1 SV=1 10 2835.6 - 160703 - - - 1.8997 - 2.109 0.488 - 80.5 1 2 0 0.0049 26 0 0 0 1.28E+07 1.01E+07 - - - 5.6961 1 221125_WJC_METTL3_EV_vs_WT_F08.16385.16385.3 1.82E-08 13/60 R.K[136.11]EAESC[160.03]DC[160.03]LQGFQLTH.S "sp|P04350|TBB4A_HUMAN,sp|A6NNZ2|TBB8B_HUMAN,sp|P07437|TBB5_HUMAN,sp|P68371|TBB4B_HUMAN,sp|Q3ZCM7|TBB8_HUMAN,tr|Q5ST81|Q5ST81_HUMAN,tr|Q5JP53|Q5JP53_HUMAN,tr|M0R042|M0R042_HUMAN,tr|A0A075B736|A0A075B736_HUMAN,tr|M0R1I1|M0R1I1_HUMAN,tr|Q5SQY0|Q5SQY0_HUMAN" 11 1929.844 0.65 119336 16385 3 1929.850497 644.2886 Tubulin beta-4A chain OS=Homo sapiens OX=9606 GN=TUBB4A PE=1 SV=2 4.65 2835.7 - 486165 - - - 3.3417 - 3.085 0.675 - 270.6 1 1 0 0.0065 16 0 0 0 4.97E+06 7.62E+06 - - - 8.9544 0.9489 221125_WJC_METTL3_EV_vs_WT_F08.16386.16386.3 2.06E-06 Nov-60 R.KEAESC[160.03]DC[160.03]LQGFQLTH.S "sp|P04350|TBB4A_HUMAN,sp|A6NNZ2|TBB8B_HUMAN,sp|P07437|TBB5_HUMAN,sp|P68371|TBB4B_HUMAN,sp|Q3ZCM7|TBB8_HUMAN,tr|Q5ST81|Q5ST81_HUMAN,tr|Q5JP53|Q5JP53_HUMAN,tr|M0R042|M0R042_HUMAN,tr|A0A075B736|A0A075B736_HUMAN,tr|M0R1I1|M0R1I1_HUMAN,tr|Q5SQY0|Q5SQY0_HUMAN" 11 1921.8298 0.65 119337 16386 3 1921.819571 641.6172 Tubulin beta-4A chain OS=Homo sapiens OX=9606 GN=TUBB4A PE=1 SV=2 4.65 2835.8 - 225107 - - - -5.3475 - 2.236 0.552 - 194 1 1 0 -0.0103 16 0 0 0 4.97E+06 7.62E+06 - - - 6.7561 0.8916 221125_WJC_METTL3_EV_vs_WT_F08.16392.16392.4 0.00255 8/108 R.AAVGRPLDKHEGALETLLR.Y "sp|Q8WUM4|PDC6I_HUMAN,tr|A0A3B3IT07|A0A3B3IT07_HUMAN,tr|C9IZF9|C9IZF9_HUMAN,tr|F8WBR8|F8WBR8_HUMAN,tr|F8WEQ7|F8WEQ7_HUMAN" 5 2045.1382 0.8 119343 16392 4 2045.147111 512.2918 Programmed cell death 6-interacting protein OS=Homo sapiens OX=9606 GN=PDCD6IP PE=1 SV=1 6.8 2836.6 - 108111 - - - 4.3709 - 1.989 0.24 - 44.9 1 2 1 0.0089 19 0 0 0 1.00E+06 1.25E+06 - - - 1.5451 1 221125_WJC_METTL3_EV_vs_WT_F08.16396.16396.3 6.28E-08 20/76 R.SDQQAQVHQLLTPASAISNK[136.11].E "sp|Q8NDV7|TNR6A_HUMAN,tr|H7C269|H7C269_HUMAN" 2 2143.1113 3.84 119345 16396 3 2143.1189 715.3777 Trinucleotide repeat-containing gene 6A protein OS=Homo sapiens OX=9606 GN=TNRC6A PE=1 SV=2 6.46 2837.1 - 647280 - - - 3.5486 - 3.938 0.598 - 456.7 1 2 0 0.0076 20 0 0 0 3.77E+07 9.83E+06 - - - 8.5303 1 221125_WJC_METTL3_EV_vs_WT_F08.16403.16403.3 5.12E-06 Jul-84 R.C[160.03]SDNSSYEEPLSPISASSSTSR[166.11].R "sp|Q8IXK0|PHC2_HUMAN,tr|A0A0A0MSI2|A0A0A0MSI2_HUMAN,tr|B3KPJ4|B3KPJ4_HUMAN" 3 2370.0157 2.21 119352 16403 3 2370.01742 791.0125 Polyhomeotic-like protein 2 OS=Homo sapiens OX=9606 GN=PHC2 PE=1 SV=1 4.14 2838 - 117596 - - - 0.7325 - 1.844 0.587 - 38.2 1 2 0 0.0017 22 0 0 0 2.49E+06 1.12E+06 - - - 6.5348 1 221125_WJC_METTL3_EV_vs_WT_F08.16407.16407.4 2.15E-11 25/102 K.DHASIQMNVAEVDK[136.11]VTGR[166.11].F "sp|P63220|RS21_HUMAN,tr|Q9BYK1|Q9BYK1_HUMAN,tr|Q8WVC2|Q8WVC2_HUMAN" 3 1986.9912 0.5 119354 16407 4 1986.996728 497.7551 40S ribosomal protein S21 OS=Homo sapiens OX=9606 GN=RPS21 PE=1 SV=1 5.38 2838.6 - 988338 - - - 2.7851 - 4.219 0.639 - 893.4 1 2 1 0.0055 18 0 0 0 4.98E+07 1.00E+08 - - - 5.2795 1 221125_WJC_METTL3_EV_vs_WT_F08.16409.16409.3 3.59E-17 33/68 K.DHASIQMNVAEVDK[136.11]VTGR[166.11].F "sp|P63220|RS21_HUMAN,tr|Q9BYK1|Q9BYK1_HUMAN,tr|Q8WVC2|Q8WVC2_HUMAN" 3 1986.9912 0.63 119356 16409 3 1986.998638 663.3377 40S ribosomal protein S21 OS=Homo sapiens OX=9606 GN=RPS21 PE=1 SV=1 5.38 2838.8 - 851123 - - - 3.7464 - 5.421 0.753 - 1820.7 1 2 1 0.0074 18 0 0 0 5.99E+07 9.47E+07 - - - 11.1421 0.9999 221125_WJC_METTL3_EV_vs_WT_F08.16411.16411.3 0.000667 14/100 R.LSVGAVSSK[136.11]PTTPTIATPQTVSVPNK[136.11].V sp|Q9HBM6|TAF9B_HUMAN 1 2595.4454 1.27 119358 16411 3 2595.449901 866.1558 Transcription initiation factor TFIID subunit 9B OS=Homo sapiens OX=9606 GN=TAF9B PE=1 SV=1 10 2839.1 - 352943 - - - 1.7215 - 2.536 0.471 - 122 1 2 0 0.0045 26 0 0 0 1.28E+07 1.01E+07 - - - 5.9309 1 221125_WJC_METTL3_EV_vs_WT_F08.16412.16412.4 1.57E-13 24/102 K.DHASIQMNVAEVDKVTGR.F "sp|P63220|RS21_HUMAN,tr|Q9BYK1|Q9BYK1_HUMAN,tr|Q8WVC2|Q8WVC2_HUMAN" 3 1968.9687 0.49 119359 16412 4 1968.978026 493.2495 40S ribosomal protein S21 OS=Homo sapiens OX=9606 GN=RPS21 PE=1 SV=1 5.38 2839.2 - 335558 - - - 4.7243 - 4.347 0.637 - 890.4 1 2 1 0.0093 18 0 0 0 4.93E+07 1.00E+08 - - - 5.2713 0.9999 221125_WJC_METTL3_EV_vs_WT_F08.16413.16413.3 7.62E-09 13/104 R.LAPASNMTSQRPVSSTGINFDNPSVQK.A sp|Q9HCD5|NCOA5_HUMAN 1 2845.4029 1.92 119360 16413 3 2845.414961 949.4749 Nuclear receptor coactivator 5 OS=Homo sapiens OX=9606 GN=NCOA5 PE=1 SV=2 8.75 2839.4 - 228817 - - - 4.2542 - 2.901 0.612 - 148.6 1 2 0 0.0121 27 0 0 0 1.15E+08 5.99E+07 - - - 7.8101 1 221125_WJC_METTL3_EV_vs_WT_F08.16418.16418.3 3.42E-10 27/100 R.AGEARPGPTAESASGPSEDPSVNFLK.N "sp|Q13501|SQSTM_HUMAN,tr|E9PFW8|E9PFW8_HUMAN,tr|E7EMC7|E7EMC7_HUMAN" 3 2570.2249 2.44 119363 16418 3 2570.23191 857.7489 Sequestosome-1 OS=Homo sapiens OX=9606 GN=SQSTM1 PE=1 SV=1 4.41 2839.9 - 589421 - - - 2.7371 - 5.069 0.667 - 639.4 1 2 0 0.007 26 0 0 0 2.42E+07 9.92E+06 - - - 9.7087 1 221125_WJC_METTL3_EV_vs_WT_F08.16419.16419.3 1.07E-11 15/104 R.LAPASNMTSQR[166.11]PVSSTGINFDNPSVQK[136.11].A sp|Q9HCD5|NCOA5_HUMAN 1 2863.4253 1.92 119364 16419 3 2863.434583 955.4824 Nuclear receptor coactivator 5 OS=Homo sapiens OX=9606 GN=NCOA5 PE=1 SV=2 8.75 2840.1 - 311625 - - - 3.2328 - 3.252 0.668 - 184.9 1 2 0 0.0093 27 0 0 0 1.15E+08 5.99E+07 - - - 8.698 1 221125_WJC_METTL3_EV_vs_WT_F08.16421.16421.3 1.24E-15 32/68 K.DHASIQMNVAEVDKVTGR.F "sp|P63220|RS21_HUMAN,tr|Q9BYK1|Q9BYK1_HUMAN,tr|Q8WVC2|Q8WVC2_HUMAN" 3 1968.9687 0.52 119366 16421 3 1968.971032 657.3302 40S ribosomal protein S21 OS=Homo sapiens OX=9606 GN=RPS21 PE=1 SV=1 5.38 2840.3 - 500083 - - - 1.1722 - 5.557 0.679 - 1482.8 1 2 1 0.0023 18 0 0 0 4.87E+07 9.41E+07 - - - 10.3802 0.9981 221125_WJC_METTL3_EV_vs_WT_F08.16423.16423.4 1.55E-06 14/198 R.SDSPVPTAPTSGGPK[136.11]PSTASAVPELATDPELEK[136.11]K[136.11].L "sp|Q86U44|MTA70_HUMAN,tr|B4E349|B4E349_HUMAN,tr|F5H6D8|F5H6D8_HUMAN,tr|B4DTN4|B4DTN4_HUMAN" 4 3384.7363 0 119368 16423 4 3385.745329 847.1913 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 4.51 2840.6 - 167303 - - - 298.1231 - 2.459 0.516 - 65.7 1 2 0 1.0091 34 0 0 0 8.81E+04 4.35E+08 - - - 3.7061 1 221125_WJC_METTL3_EV_vs_WT_F08.16427.16427.3 1.30E-11 18/72 R.GGHMDDGGYSMNFNMSSSR[166.11].G "sp|Q96E39|RMXL1_HUMAN,sp|P38159|RBMX_HUMAN,tr|A0A1B0GUK8|A0A1B0GUK8_HUMAN,tr|H3BT71|H3BT71_HUMAN,tr|H0Y6E7|H0Y6E7_HUMAN" 5 2058.7858 1.36 119370 16427 3 2058.791814 687.2692 "RNA binding motif protein, X-linked-like-1 OS=Homo sapiens OX=9606 GN=RBMXL1 PE=1 SV=1" 5.21 2841.1 - 926970 - - - 2.9386 - 3.731 0.792 - 575.6 1 2 0 0.006 19 0 0 0 5.62E+07 4.13E+07 - - - 10.6032 0.9953 221125_WJC_METTL3_EV_vs_WT_F08.16428.16428.3 0.0018 Dec-44 R.TVITEEFKVPDK.M sp|Q96I24|FUBP3_HUMAN 1 1404.75 2.13 119371 16428 3 1404.756211 469.2573 Far upstream element-binding protein 3 OS=Homo sapiens OX=9606 GN=FUBP3 PE=1 SV=2 4.68 2841.3 - 584469 - - - 4.388 - 2.557 0.367 - 136.4 1 2 1 0.0062 12 0 0 0 9.18E+06 4.30E+06 - - - 5.2323 1 221125_WJC_METTL3_EV_vs_WT_F08.16429.16429.3 2.60E-10 17/72 R.GLLQDDAHPTLVTYADHSK[136.11].L "sp|Q86U44|MTA70_HUMAN,tr|F5H6D8|F5H6D8_HUMAN,tr|H0YFV6|H0YFV6_HUMAN,tr|B4DTN4|B4DTN4_HUMAN" 4 2088.0367 0.02 119372 16429 3 2088.041334 697.0195 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 5.13 2841.4 - 736722 - - - 2.2035 - 3.241 0.598 - 295.2 1 2 0 0.0046 19 0 0 0 1.76E+05 1.08E+07 - - - 8.0947 0.999 221125_WJC_METTL3_EV_vs_WT_F08.16430.16430.3 7.99E-05 16/52 K.KKELEEIVQPIISK.L "sp|P11021|BIP_HUMAN,tr|A0A7P0TB36|A0A7P0TB36_HUMAN,tr|A0A7P0TAI0|A0A7P0TAI0_HUMAN" 3 1652.9713 0.53 119373 16430 3 1652.978383 551.9977 Endoplasmic reticulum chaperone BiP OS=Homo sapiens OX=9606 GN=HSPA5 PE=1 SV=2 6.23 2841.5 - 295368 - - - 4.3013 - 3.098 0.49 - 410.9 1 2 1 0.0071 14 0 0 0 9.03E+07 1.70E+08 - - - 7.0061 0.9998 221125_WJC_METTL3_EV_vs_WT_F08.16435.16435.3 1.60E-06 18/52 K.K[136.11]K[136.11]ELEEIVQPIISK[136.11].L "sp|P11021|BIP_HUMAN,tr|A0A7P0TB36|A0A7P0TB36_HUMAN,tr|A0A7P0TAI0|A0A7P0TAI0_HUMAN" 3 1677.0139 0.53 119376 16435 3 1677.019121 560.0119 Endoplasmic reticulum chaperone BiP OS=Homo sapiens OX=9606 GN=HSPA5 PE=1 SV=2 6.23 2842.2 - 1.60E+06 - - - 3.1294 - 3.019 0.588 - 518.1 1 2 1 0.0052 14 0 0 0 9.03E+07 1.70E+08 - - - 8.0305 1 221125_WJC_METTL3_EV_vs_WT_F08.16436.16436.4 5.91E-12 24/138 R.IVSR[166.11]PEELR[166.11]EDDVGTGAGLLEIK[136.11]K[136.11].L "sp|P49368|TCPG_HUMAN,tr|B4DUR8|B4DUR8_HUMAN" 2 2659.463 0.24 119377 16436 4 2659.468056 665.873 T-complex protein 1 subunit gamma OS=Homo sapiens OX=9606 GN=CCT3 PE=1 SV=4 4.66 2842.3 - 839110 - - - 1.888 - 3.987 0.653 - 397 1 2 1 0.005 24 0 0 0 3.92E+07 1.63E+08 - - - 5.3522 0.9999 221125_WJC_METTL3_EV_vs_WT_F08.16439.16439.4 8.32E-05 14/78 K.K[136.11]K[136.11]ELEEIVQPIISK[136.11].L "sp|P11021|BIP_HUMAN,tr|A0A7P0TB36|A0A7P0TB36_HUMAN,tr|A0A7P0TAI0|A0A7P0TAI0_HUMAN" 3 1677.0139 1.9 119380 16439 4 1677.016051 420.2607 Endoplasmic reticulum chaperone BiP OS=Homo sapiens OX=9606 GN=HSPA5 PE=1 SV=2 6.23 2842.7 - 301088 - - - 1.2987 - 2.552 0.515 - 200.5 1 2 1 0.0022 14 0 0 0 1.04E+07 5.46E+06 - - - 4.0489 0.9997 221125_WJC_METTL3_EV_vs_WT_F08.16444.16444.3 2.76E-06 Oct-52 K.K[136.11]GPGEVAGTVTGQK[136.11].R "sp|Q86U44|MTA70_HUMAN,tr|F5H6D8|F5H6D8_HUMAN,tr|H0YFV6|H0YFV6_HUMAN,tr|B4DTN4|B4DTN4_HUMAN" 4 1343.738 0.001 119385 16444 3 1343.742683 448.9199 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 8.59 2843.4 - 169433 - - - 3.5007 - 2.284 0.457 - 147.9 1 2 0 0.0047 14 0 0 0 0.00E+00 3.19E+06 - - - 5.8287 1 221125_WJC_METTL3_EV_vs_WT_F08.16447.16447.4 8.90E-06 17/144 R.QQSHFAMMHGGTGFAGIDSSSPEVK[136.11].G sp|Q15365|PCBP1_HUMAN 1 2613.1832 0.51 119386 16447 4 2613.185723 654.3031 Poly(rC)-binding protein 1 OS=Homo sapiens OX=9606 GN=PCBP1 PE=1 SV=2 5.99 2843.8 - 960461 - - - 0.9819 - 2.788 0.496 - 138.1 1 2 0 0.0026 25 0 0 0 2.93E+07 5.78E+07 - - - 3.8687 0.9999 221125_WJC_METTL3_EV_vs_WT_F08.16448.16448.4 4.34E-05 12/156 R.LAPASNMTSQR[166.11]PVSSTGINFDNPSVQK[136.11].A sp|Q9HCD5|NCOA5_HUMAN 1 2863.4253 2 119387 16448 4 2863.429176 716.8636 Nuclear receptor coactivator 5 OS=Homo sapiens OX=9606 GN=NCOA5 PE=1 SV=2 8.75 2843.9 - 493920 - - - 1.3445 - 2.723 0.427 - 67.8 1 2 0 0.0039 27 0 0 0 2.12E+07 1.06E+07 - - - 3.255 1 221125_WJC_METTL3_EV_vs_WT_F08.16449.16449.3 9.37E-10 14/76 K.QTTVSNSQQAYQEAFEISK[136.11]K[136.11].E sp|P31946|1433B_HUMAN 1 2302.1412 1.18 119388 16449 3 2302.145038 768.3877 14-3-3 protein beta\alpha OS=Homo sapiens OX=9606 GN=YWHAB PE=1 SV=3 6.14 2844.1 - 444994 - - - 1.665 - 3.079 0.535 - 327.7 1 2 0 0.0038 20 0 0 0 1.19E+07 1.01E+07 - - - 7.232 0.9916 221125_WJC_METTL3_EV_vs_WT_F08.16450.16450.4 2.08E-05 13/78 K.KKELEEIVQPIISK.L "sp|P11021|BIP_HUMAN,tr|A0A7P0TB36|A0A7P0TB36_HUMAN,tr|A0A7P0TAI0|A0A7P0TAI0_HUMAN" 3 1652.9713 1.89 119389 16450 4 1652.975173 414.2501 Endoplasmic reticulum chaperone BiP OS=Homo sapiens OX=9606 GN=HSPA5 PE=1 SV=2 6.23 2844.2 - 222389 - - - 2.3594 - 2.597 0.282 - 202.2 1 2 1 0.0039 14 0 0 0 1.03E+07 5.46E+06 - - - 2.0268 0.9997 221125_WJC_METTL3_EV_vs_WT_F08.16455.16455.4 1.62E-05 16/156 R.LAPASNMTSQRPVSSTGINFDNPSVQK.A sp|Q9HCD5|NCOA5_HUMAN 1 2845.4029 2 119392 16455 4 2845.409612 712.358 Nuclear receptor coactivator 5 OS=Homo sapiens OX=9606 GN=NCOA5 PE=1 SV=2 8.75 2844.9 - 1.49E+06 - - - 2.3744 - 3.1 0.393 - 118.5 1 2 0 0.0068 27 0 0 0 2.12E+07 1.06E+07 - - - 2.9988 0.9999 221125_WJC_METTL3_EV_vs_WT_F08.16456.16456.3 3.88E-06 14/76 K.QTTVSNSQQAYQEAFEISKK.E sp|P31946|1433B_HUMAN 1 2286.1128 1.18 119393 16456 3 2286.117666 763.0449 14-3-3 protein beta\alpha OS=Homo sapiens OX=9606 GN=YWHAB PE=1 SV=3 6.14 2845 - 518664 - - - 2.1263 - 2.462 0.458 - 156.1 1 2 0 0.0049 20 0 0 0 1.19E+07 1.01E+07 - - - 5.8307 0.9996 221125_WJC_METTL3_EV_vs_WT_F08.16457.16457.3 2.37E-05 15/52 K.SGK[136.11]WEGLVYAPPGK[136.11].E "sp|Q9Y2W1|TR150_HUMAN,tr|A0A3B3ITZ9|A0A3B3ITZ9_HUMAN" 2 1503.8057 2.6 119394 16457 3 1503.809605 502.2758 Thyroid hormone receptor-associated protein 3 OS=Homo sapiens OX=9606 GN=THRAP3 PE=1 SV=2 8.22 2845.1 - 512762 - - - 2.62 - 2.776 0.468 - 251.6 1 2 1 0.0039 14 0 0 0 2.72E+07 1.04E+07 - - - 6.47 0.9997 221125_WJC_METTL3_EV_vs_WT_F08.16458.16458.4 7.02E-05 17/126 R.R[166.11]GEQADHFTQTPLDPGSQVLVR[166.11].V "sp|Q9BTE6|AASD1_HUMAN,tr|B3KSP9|B3KSP9_HUMAN,tr|C9J5N1|C9J5N1_HUMAN" 3 2470.2468 0.47 119395 16458 4 2470.257948 618.569 Alanyl-tRNA editing protein Aarsd1 OS=Homo sapiens OX=9606 GN=AARSD1 PE=1 SV=2 5.38 2845.3 - 350407 - - - 4.523 - 2.986 0.509 - 259.6 1 2 0 0.0112 22 0 0 0 2.29E+06 4.90E+06 - - - 4.0112 1 221125_WJC_METTL3_EV_vs_WT_F08.16461.16461.3 1.96E-10 19/84 R.KSEYTQPTPIQC[160.03]QGVPVALSGR.D "sp|Q86XP3|DDX42_HUMAN,tr|A0A0A0MSJ0|A0A0A0MSJ0_HUMAN" 2 2415.2216 2.26 119398 16461 3 2415.226724 806.0812 ATP-dependent RNA helicase DDX42 OS=Homo sapiens OX=9606 GN=DDX42 PE=1 SV=1 8.2 2845.6 - 262790 - - - 2.1033 - 3.537 0.607 - 207.8 1 2 0 0.0051 22 0 0 0 1.99E+07 8.81E+06 - - - 8.3011 1 221125_WJC_METTL3_EV_vs_WT_F08.16467.16467.4 6.87E-10 19/132 R.SLSTTNVFAC[160.03]SDRPTVIYSSNHK.L "sp|Q16531|DDB1_HUMAN,tr|A0A7P0TAK7|A0A7P0TAK7_HUMAN,tr|A0A7P0T870|A0A7P0T870_HUMAN,tr|A0A7P0TB30|A0A7P0TB30_HUMAN,tr|A0A7P0Z3Z5|A0A7P0Z3Z5_HUMAN,tr|F5GY55|F5GY55_HUMAN,tr|A0A7P0Z4B9|A0A7P0Z4B9_HUMAN,tr|A0A7P0T965|A0A7P0T965_HUMAN" 8 2583.2388 0.56 119402 16467 4 2583.245351 646.817 DNA damage-binding protein 1 OS=Homo sapiens OX=9606 GN=DDB1 PE=1 SV=1 7.95 2846.4 - 908393 - - - 2.5549 - 3.525 0.557 - 233.4 1 2 0 0.0066 23 0 0 0 1.91E+07 3.40E+07 - - - 4.4805 1 221125_WJC_METTL3_EV_vs_WT_F08.16468.16468.3 1.14E-10 19/88 K.ESVTDYTTPSSSLPNTVATNNTK.M "sp|Q9Y520|PRC2C_HUMAN,tr|E7EPN9|E7EPN9_HUMAN,tr|A0A2R8Y7F4|A0A2R8Y7F4_HUMAN,tr|A0A2R8YET2|A0A2R8YET2_HUMAN" 4 2426.1449 3.38 119403 16468 3 2426.149207 809.7222 Protein PRRC2C OS=Homo sapiens OX=9606 GN=PRRC2C PE=1 SV=4 4.37 2846.6 - 765735 - - - 1.7781 - 3.405 0.601 - 295.7 1 2 0 0.0043 23 0 0 0 8.02E+07 2.37E+07 - - - 8.1137 1 221125_WJC_METTL3_EV_vs_WT_F08.16470.16470.3 1.72E-08 13/96 R.QQSHFAMMHGGTGFAGIDSSSPEVK[136.11].G sp|Q15365|PCBP1_HUMAN 1 2613.1832 0.32 119405 16470 3 2613.186488 872.0683 Poly(rC)-binding protein 1 OS=Homo sapiens OX=9606 GN=PCBP1 PE=1 SV=2 5.99 2846.8 - 435061 - - - 1.2747 - 2.832 0.663 - 121.5 1 2 0 0.0033 25 0 0 0 2.52E+06 7.99E+06 - - - 8.3258 0.9999 221125_WJC_METTL3_EV_vs_WT_F08.16476.16476.4 1.35E-05 Dec-96 R.VK[136.11]PAPDETSFSEALLK[136.11]R[166.11].N "sp|Q12905|ILF2_HUMAN,tr|B4DY09|B4DY09_HUMAN,tr|X6R6Z1|X6R6Z1_HUMAN,tr|A0A0A0MRL0|A0A0A0MRL0_HUMAN" 4 1913.0468 1.29 119410 16476 4 1913.051527 479.269 Interleukin enhancer-binding factor 2 OS=Homo sapiens OX=9606 GN=ILF2 PE=1 SV=2 6.15 2847.6 - 226922 - - - 2.4458 - 2.779 0.529 - 89.5 1 2 0 0.0047 17 0 0 0 5.26E+06 4.07E+06 - - - 4.184 1 221125_WJC_METTL3_EV_vs_WT_F08.16480.16480.4 1.85E-06 28/138 R.IVSRPEELREDDVGTGAGLLEIKK.L "sp|P49368|TCPG_HUMAN,tr|B4DUR8|B4DUR8_HUMAN" 2 2623.4181 0.24 119413 16480 4 2623.422294 656.8618 T-complex protein 1 subunit gamma OS=Homo sapiens OX=9606 GN=CCT3 PE=1 SV=4 4.66 2848 - 2.42E+06 - - - 1.6006 - 4.181 0.636 - 538.1 1 2 1 0.0042 24 0 0 0 3.92E+07 1.63E+08 - - - 5.2197 0.9999 221125_WJC_METTL3_EV_vs_WT_F08.16481.16481.3 8.46E-11 17/56 K.SKQEALKNDLVEALK.R tr|B1AK88|B1AK88_HUMAN 1 1684.936 0.88 119414 16481 3 1684.938494 562.6526 F-actin-capping protein subunit beta OS=Homo sapiens OX=9606 GN=CAPZB PE=1 SV=1 5.9 2848.1 - 602415 - - - 1.5098 - 3.214 0.571 - 225.2 1 2 2 0.0025 15 0 0 0 1.67E+07 1.90E+07 - - - 7.9519 1 221125_WJC_METTL3_EV_vs_WT_F08.16483.16483.3 1.10E-11 28/84 R.HIQEHYGGTATFYLSQAADGAK[136.11].V "sp|P51570|GALK1_HUMAN,tr|K7EII7|K7EII7_HUMAN" 2 2372.1277 1.54 119416 16483 3 2372.135559 791.7165 Galactokinase OS=Homo sapiens OX=9606 GN=GALK1 PE=1 SV=1 5.99 2848.4 - 469117 - - - 3.324 - 4.702 0.706 - 982 1 2 0 0.0079 22 0 0 0 5.37E+07 3.49E+07 - - - 10.079 0.9997 221125_WJC_METTL3_EV_vs_WT_F08.16485.16485.4 0.00162 13/90 K.AEDNFEDIITKPPVRK.F "sp|Q9Y6G9|DC1L1_HUMAN,tr|E9PHI6|E9PHI6_HUMAN" 2 1870.9789 0.93 119418 16485 4 1870.980001 468.752 Cytoplasmic dynein 1 light intermediate chain 1 OS=Homo sapiens OX=9606 GN=DYNC1LI1 PE=1 SV=3 4.78 2848.6 - 341136 - - - 0.6002 - 2.301 0.354 - 109.7 1 2 0 0.0011 16 0 0 0 7.19E+06 7.75E+06 - - - 2.6005 0.9999 221125_WJC_METTL3_EV_vs_WT_F08.16486.16486.4 0.000152 Dec-96 R.VKPAPDETSFSEALLKR.N "sp|Q12905|ILF2_HUMAN,tr|B4DY09|B4DY09_HUMAN,tr|X6R6Z1|X6R6Z1_HUMAN,tr|A0A0A0MRL0|A0A0A0MRL0_HUMAN" 4 1887.0102 1.29 119419 16486 4 1887.011278 472.7598 Interleukin enhancer-binding factor 2 OS=Homo sapiens OX=9606 GN=ILF2 PE=1 SV=2 6.15 2848.7 - 315905 - - - 0.5829 - 2.239 0.436 - 104.4 1 2 0 0.0011 17 0 0 0 5.26E+06 4.07E+06 - - - 3.3005 0.9838 221125_WJC_METTL3_EV_vs_WT_F08.16487.16487.4 0.0246 Sep-84 K.SKQEALKNDLVEALK.R tr|B1AK88|B1AK88_HUMAN 1 1684.936 0.84 119420 16487 4 1684.938383 422.2413 F-actin-capping protein subunit beta OS=Homo sapiens OX=9606 GN=CAPZB PE=1 SV=1 5.9 2848.9 - 288185 - - - 1.444 - 1.854 0.24 - 63.4 1 2 2 0.0024 15 0 0 0 4.97E+06 5.90E+06 - - - 1.5352 1 221125_WJC_METTL3_EV_vs_WT_F08.16492.16492.3 3.78E-13 31/84 R.HIQEHYGGTATFYLSQAADGAK.V "sp|P51570|GALK1_HUMAN,tr|K7EII7|K7EII7_HUMAN" 2 2364.1135 1.54 119423 16492 3 2364.114676 789.0451 Galactokinase OS=Homo sapiens OX=9606 GN=GALK1 PE=1 SV=1 5.99 2849.6 - 2.29E+06 - - - 0.5084 - 5.016 0.73 - 1265.4 1 2 0 0.0012 22 0 0 0 5.37E+07 3.49E+07 - - - 10.5017 0.9999 221125_WJC_METTL3_EV_vs_WT_F08.16493.16493.3 0.401 16/92 R.IVSR[166.11]PEELR[166.11]EDDVGTGAGLLEIK[136.11]K[136.11].L "sp|P49368|TCPG_HUMAN,tr|B4DUR8|B4DUR8_HUMAN" 2 2659.463 0.11 119424 16493 3 2659.465184 887.495 T-complex protein 1 subunit gamma OS=Homo sapiens OX=9606 GN=CCT3 PE=1 SV=4 4.66 2849.7 - 701940 - - - 0.8081 - 2.803 0.53 - 123.4 1 2 1 0.0021 24 0 0 0 8.72E+05 8.17E+06 - - - 6.8423 0.9999 221125_WJC_METTL3_EV_vs_WT_F08.16495.16495.3 0.00148 17/56 K.SK[136.11]QEALK[136.11]NDLVEALK[136.11].R tr|B1AK88|B1AK88_HUMAN 1 1708.9786 0.88 119426 16495 3 1708.979125 570.6668 F-actin-capping protein subunit beta OS=Homo sapiens OX=9606 GN=CAPZB PE=1 SV=1 5.9 2849.9 - 932930 - - - 0.3365 - 2.996 0.482 - 195.5 1 2 2 0.0006 15 0 0 0 1.67E+07 1.90E+07 - - - 6.7769 1 221125_WJC_METTL3_EV_vs_WT_F08.16496.16496.4 3.25E-10 26/144 R.SVR[166.11]PTDSNVSPAISIHEIGAVGATK[136.11].T "sp|P46020|KPB1_HUMAN,tr|A6NMN0|A6NMN0_HUMAN,tr|A6NIT2|A6NIT2_HUMAN" 3 2523.3412 1.01 119427 16496 4 2523.343411 631.8426 "Phosphorylase b kinase regulatory subunit alpha, skeletal muscle isoform OS=Homo sapiens OX=9606 GN=PHKA1 PE=1 SV=2" 6.47 2850 - 616156 - - - 0.8818 - 4.729 0.545 - 436 1 2 0 0.0022 25 0 0 0 1.93E+07 1.92E+07 - - - 4.4633 1 221125_WJC_METTL3_EV_vs_WT_F08.16498.16498.2 4.97E-10 17/44 K.ESVTDYTTPSSSLPNTVATNNTK.M "sp|Q9Y520|PRC2C_HUMAN,tr|E7EPN9|E7EPN9_HUMAN,tr|A0A2R8Y7F4|A0A2R8Y7F4_HUMAN,tr|A0A2R8YET2|A0A2R8YET2_HUMAN" 4 2426.1449 2.34 119429 16498 2 2428.145447 1214.0797 Protein PRRC2C OS=Homo sapiens OX=9606 GN=PRRC2C PE=1 SV=4 4.37 2850.3 - 247718 - - - 824.5814 - 3.188 0.746 - 548.7 1 2 0 2.0006 23 0 0 0 1.32E+07 5.63E+06 - - - 6.7732 0.998 221125_WJC_METTL3_EV_vs_WT_F08.16499.16499.2 0.000556 26-Oct K.K[136.11]K[136.11]ELEEIVQPIISK[136.11].L "sp|P11021|BIP_HUMAN,tr|A0A7P0TB36|A0A7P0TB36_HUMAN,tr|A0A7P0TAI0|A0A7P0TAI0_HUMAN" 3 1677.0139 0.37 119430 16499 2 1677.016209 839.5142 Endoplasmic reticulum chaperone BiP OS=Homo sapiens OX=9606 GN=HSPA5 PE=1 SV=2 6.23 2850.4 - 243629 - - - 1.393 - 2.383 0.512 - 315.7 1 2 1 0.0023 14 0 0 0 2.06E+06 5.50E+06 - - - 5.001 1 221125_WJC_METTL3_EV_vs_WT_F08.16504.16504.4 1.40E-12 25/144 R.SVRPTDSNVSPAISIHEIGAVGATK.T "sp|P46020|KPB1_HUMAN,tr|A6NMN0|A6NMN0_HUMAN,tr|A6NIT2|A6NIT2_HUMAN" 3 2505.3187 1.01 119432 16504 4 2505.322831 627.337 "Phosphorylase b kinase regulatory subunit alpha, skeletal muscle isoform OS=Homo sapiens OX=9606 GN=PHKA1 PE=1 SV=2" 6.47 2851.1 - 673497 - - - 1.6425 - 5.108 0.622 - 391.4 1 2 0 0.0041 25 0 0 0 1.94E+07 1.92E+07 - - - 5.1575 0.9999 221125_WJC_METTL3_EV_vs_WT_F08.16505.16505.4 4.84E-05 18/168 R.GLPAGDVLEPVQKPHEGPGEMGKPVVIPK.E "sp|Q10472|GALT1_HUMAN,tr|K7EJV8|K7EJV8_HUMAN" 2 2974.595 1.56 119433 16505 4 2974.60228 744.656 Polypeptide N-acetylgalactosaminyltransferase 1 OS=Homo sapiens OX=9606 GN=GALNT1 PE=1 SV=1 5.53 2851.2 - 763299 - - - 2.4427 - 2.604 0.469 - 107.2 1 2 0 0.0073 29 0 0 0 1.33E+07 8.55E+06 - - - 3.6011 0.9996 221125_WJC_METTL3_EV_vs_WT_F08.16510.16510.4 4.38E-05 13/90 R.R[166.11]LDPNK[136.11]YPVPENWLHK[136.11].E "sp|P39748|FEN1_HUMAN,tr|I3L3E9|I3L3E9_HUMAN" 2 2031.0901 0.51 119438 16510 4 2031.091805 508.7798 Flap endonuclease 1 OS=Homo sapiens OX=9606 GN=FEN1 PE=1 SV=1 8.5 2851.8 - 204759 - - - 0.8641 - 2.402 0.427 - 114.5 1 2 1 0.0018 16 0 0 0 2.52E+06 4.95E+06 - - - 3.2508 1 221125_WJC_METTL3_EV_vs_WT_F08.16513.16513.4 2.07E-08 18/102 K.FAASGGFLHHMAGLSSSK.L "sp|Q9BY77|PDIP3_HUMAN,tr|F6VRR5|F6VRR5_HUMAN,tr|F8WCX5|F8WCX5_HUMAN,tr|Q8WUT1|Q8WUT1_HUMAN" 4 1803.8726 1.86 119439 16513 4 1803.87183 451.9754 Polymerase delta-interacting protein 3 OS=Homo sapiens OX=9606 GN=POLDIP3 PE=1 SV=2 8.76 2852.2 - 746931 - - - -0.4479 - 3.367 0.542 - 226.9 1 2 0 -0.0008 18 0 0 0 3.01E+07 1.62E+07 - - - 4.3592 0.9998 221125_WJC_METTL3_EV_vs_WT_F08.16514.16514.4 1.05E-05 16/102 K.FAASGGFLHHMAGLSSSK[136.11].L "sp|Q9BY77|PDIP3_HUMAN,tr|F6VRR5|F6VRR5_HUMAN,tr|F8WCX5|F8WCX5_HUMAN,tr|Q8WUT1|Q8WUT1_HUMAN" 4 1811.8868 1.86 119440 16514 4 1811.881793 453.979 Polymerase delta-interacting protein 3 OS=Homo sapiens OX=9606 GN=POLDIP3 PE=1 SV=2 8.76 2852.4 - 565572 - - - -2.7844 - 3.335 0.416 - 185.7 1 2 0 -0.005 18 0 0 0 3.00E+07 1.62E+07 - - - 3.2581 0.9993 221125_WJC_METTL3_EV_vs_WT_F08.16515.16515.3 0.0253 16/60 R.TRRDEPTGEVLSLVGK.L "sp|O75643|U520_HUMAN,tr|A0A494C1A5|A0A494C1A5_HUMAN" 2 1755.9479 1.52 119441 16515 3 1755.951357 586.3232 U5 small nuclear ribonucleoprotein 200 kDa helicase OS=Homo sapiens OX=9606 GN=SNRNP200 PE=1 SV=2 5.85 2852.5 - 765870 - - - 1.9619 - 2.803 0.381 - 353.8 1 2 1 0.0034 16 0 0 0 1.52E+07 9.95E+06 - - - 5.4314 1 221125_WJC_METTL3_EV_vs_WT_F08.16518.16518.4 4.11E-08 19/126 K.TVGFGTNNSEHITYLEHNPYEK.F sp|Q99459|CDC5L_HUMAN 1 2549.1823 1.43 119442 16518 4 2549.184685 638.3028 Cell division cycle 5-like protein OS=Homo sapiens OX=9606 GN=CDC5L PE=1 SV=2 5.31 2852.9 - 878784 - - - 0.9427 - 3.837 0.535 - 199.2 1 2 0 0.0024 22 0 0 0 1.86E+07 1.30E+07 - - - 4.322 0.9998 221125_WJC_METTL3_EV_vs_WT_F08.16519.16519.3 4.70E-06 15/52 K.SGKWEGLVYAPPGK.E "sp|Q9Y2W1|TR150_HUMAN,tr|A0A3B3ITZ9|A0A3B3ITZ9_HUMAN" 2 1487.7773 2.5 119443 16519 3 1487.776919 496.933 Thyroid hormone receptor-associated protein 3 OS=Homo sapiens OX=9606 GN=THRAP3 PE=1 SV=2 8.22 2853 - 786524 - - - -0.2326 - 2.665 0.458 - 218.3 1 2 1 -0.0003 14 0 0 0 2.81E+07 1.12E+07 - - - 6.2511 1 221125_WJC_METTL3_EV_vs_WT_F08.16521.16521.2 5.26E-13 Dec-44 K.ESVTDYTTPSSSLPNTVATNNTK[136.11].M "sp|Q9Y520|PRC2C_HUMAN,tr|E7EPN9|E7EPN9_HUMAN,tr|A0A2R8Y7F4|A0A2R8Y7F4_HUMAN,tr|A0A2R8YET2|A0A2R8YET2_HUMAN" 4 2434.1591 2.34 119445 16521 2 2434.157265 1218.0868 Protein PRRC2C OS=Homo sapiens OX=9606 GN=PRRC2C PE=1 SV=4 4.37 2853.2 - 277325 - - - -0.751 - 2.802 0.726 - 223 1 2 0 -0.0018 23 0 0 0 1.32E+07 5.63E+06 - - - 6.9358 1 221125_WJC_METTL3_EV_vs_WT_F08.16526.16526.3 7.55E-08 20/80 K.YQGDGIVEDEEETMENNEEKK.D "sp|Q9NYF8|BCLF1_HUMAN,tr|H0YF63|H0YF63_HUMAN,tr|E9PK91|E9PK91_HUMAN,tr|H0YF14|H0YF14_HUMAN" 4 2485.0439 2.39 119448 16526 3 2485.042185 829.3552 Bcl-2-associated transcription factor 1 OS=Homo sapiens OX=9606 GN=BCLAF1 PE=1 SV=2 3.89 2853.9 - 1.39E+06 - - - -0.6736 - 3.83 0.643 - 340.4 1 2 0 -0.0017 21 0 0 0 1.55E+08 6.50E+07 - - - 8.9278 1 221125_WJC_METTL3_EV_vs_WT_F08.16527.16527.4 3.46E-05 16/132 K.VGPYHNPQETYHYYQLPVC[160.03]C[160.03]PEK.L "sp|O15321|TM9S1_HUMAN,tr|E9PJC4|E9PJC4_HUMAN,tr|E9PSI1|E9PSI1_HUMAN,tr|E9PL78|E9PL78_HUMAN,tr|E9PJM1|E9PJM1_HUMAN,tr|E9PS99|E9PS99_HUMAN,tr|E9PQY7|E9PQY7_HUMAN,tr|E9PMQ9|E9PMQ9_HUMAN" 8 2878.2843 1.51 119449 16527 4 2878.284225 720.5784 Transmembrane 9 superfamily member 1 OS=Homo sapiens OX=9606 GN=TM9SF1 PE=2 SV=2 6 2854 - 391694 - - - -0.0334 - 2.42 0.546 - 170.1 1 2 0 -0.0001 23 0 0 0 1.29E+07 8.54E+06 - - - 4.2647 0.9978 221125_WJC_METTL3_EV_vs_WT_F08.16529.16529.4 0.00135 13/114 R.RAFREEFGAEPELAVSAPGR.V "sp|P51570|GALK1_HUMAN,tr|K7ERJ9|K7ERJ9_HUMAN,tr|K7ERN9|K7ERN9_HUMAN,tr|K7EII7|K7EII7_HUMAN" 4 2188.1025 0.94 119451 16529 4 2188.102961 548.0329 Galactokinase OS=Homo sapiens OX=9606 GN=GALK1 PE=1 SV=1 4.95 2854.2 - 302498 - - - 0.2038 - 2.415 0.321 - 129.1 1 2 1 0.0004 20 0 0 0 3.49E+06 3.72E+06 - - - 2.3146 1 221125_WJC_METTL3_EV_vs_WT_F08.16532.16532.4 4.78E-09 27/126 R.HIQEHYGGTATFYLSQAADGAK[136.11].V "sp|P51570|GALK1_HUMAN,tr|K7EII7|K7EII7_HUMAN" 2 2372.1277 1.83 119452 16532 4 2372.12639 594.0392 Galactokinase OS=Homo sapiens OX=9606 GN=GALK1 PE=1 SV=1 5.99 2854.6 - 4.88E+06 - - - -0.5413 - 3.738 0.54 - 415.9 1 2 0 -0.0013 22 0 0 0 1.29E+08 7.04E+07 - - - 4.3572 0.9999 221125_WJC_METTL3_EV_vs_WT_F08.16533.16533.4 0.000477 14/168 R.GLPAGDVLEPVQK[136.11]PHEGPGEMGK[136.11]PVVIPK[136.11].E "sp|Q10472|GALT1_HUMAN,tr|K7EJV8|K7EJV8_HUMAN" 2 2998.6376 1.56 119453 16533 4 2998.639243 750.6667 Polypeptide N-acetylgalactosaminyltransferase 1 OS=Homo sapiens OX=9606 GN=GALNT1 PE=1 SV=1 5.53 2854.8 - 773784 - - - 0.5432 - 2.257 0.427 - 51.2 1 2 0 0.0016 29 0 0 0 1.33E+07 8.55E+06 - - - 3.193 0.9992 221125_WJC_METTL3_EV_vs_WT_F08.16536.16536.4 0.0166 18/126 K.SSQIGAVVSHQSSVIPDREYLR.K "sp|Q9NVS9|PNPO_HUMAN,tr|J3QQZ9|J3QQZ9_HUMAN,tr|J3QQV6|J3QQV6_HUMAN" 3 2427.2506 1.21 119456 16536 4 2427.247487 607.8199 Pyridoxine-5'-phosphate oxidase OS=Homo sapiens OX=9606 GN=PNPO PE=1 SV=1 6.47 2855.1 - 729842 - - - -1.2974 - 3.257 0.367 - 205.1 1 2 1 -0.0031 22 0 0 0 6.92E+06 5.74E+06 - - - 2.8059 0.9985 221125_WJC_METTL3_EV_vs_WT_F08.16537.16537.3 9.76E-06 16/108 K.QNPSLPAPQTLAGGNPETAQPHAGTLPR.P "sp|Q68EM7|RHG17_HUMAN,tr|I3L3P1|I3L3P1_HUMAN,tr|I3L4Y5|I3L4Y5_HUMAN,tr|I3L460|I3L460_HUMAN" 4 2819.4315 2.22 119457 16537 3 2819.42849 940.8178 Rho GTPase-activating protein 17 OS=Homo sapiens OX=9606 GN=ARHGAP17 PE=1 SV=1 6.75 2855.2 - 350084 - - - -1.0513 - 2.786 0.6 - 152.4 1 1 0 -0.003 28 0 0 0 1.04E+07 4.66E+06 - - - 7.5858 0.9999 221125_WJC_METTL3_EV_vs_WT_F08.16538.16538.3 6.03E-06 15/96 K.LGHPEALSAGTGSPQPPSFTYAQQR[166.11].E "sp|Q15942|ZYX_HUMAN,tr|H7C3D3|H7C3D3_HUMAN,tr|H0Y2Y8|H0Y2Y8_HUMAN" 3 2606.2753 6.98 119458 16538 3 2606.277449 869.7657 Zyxin OS=Homo sapiens OX=9606 GN=ZYX PE=1 SV=1 6.75 2855.4 - 218763 - - - 0.8307 - 2.24 0.446 - 127.7 1 2 0 0.0022 25 0 0 0 9.78E+06 1.40E+06 - - - 5.3673 1 221125_WJC_METTL3_EV_vs_WT_F08.16539.16539.4 3.61E-06 14/108 K.DRPENVHGGILADDMGLGK.T "sp|Q14527|HLTF_HUMAN,tr|A0A0C4DGA6|A0A0C4DGA6_HUMAN" 2 1992.9687 2.19 119459 16539 4 1992.969181 499.2495 Helicase-like transcription factor OS=Homo sapiens OX=9606 GN=HLTF PE=1 SV=2 4.66 2855.5 - 216381 - - - 0.2293 - 3.103 0.513 - 135.6 1 2 0 0.0005 19 0 0 0 4.69E+06 2.14E+06 - - - 4.0741 1 221125_WJC_METTL3_EV_vs_WT_F08.16543.16543.3 2.83E-12 19/68 K.FAASGGFLHHMAGLSSSK.L "sp|Q9BY77|PDIP3_HUMAN,tr|F6VRR5|F6VRR5_HUMAN,tr|F8WCX5|F8WCX5_HUMAN,tr|Q8WUT1|Q8WUT1_HUMAN" 4 1803.8726 1.87 119461 16543 3 1803.875024 602.2982 Polymerase delta-interacting protein 3 OS=Homo sapiens OX=9606 GN=POLDIP3 PE=1 SV=2 8.76 2856 - 1.94E+06 - - - 1.3227 - 3.954 0.649 - 365.8 1 2 0 0.0024 18 0 0 0 1.92E+07 1.03E+07 - - - 9.1983 1 221125_WJC_METTL3_EV_vs_WT_F08.16544.16544.4 4.11E-09 20/126 K.TVGFGTNNSEHITYLEHNPYEK[136.11].F sp|Q99459|CDC5L_HUMAN 1 2557.1965 1.43 119462 16544 4 2557.193962 640.3064 Cell division cycle 5-like protein OS=Homo sapiens OX=9606 GN=CDC5L PE=1 SV=2 5.31 2856.1 - 1.34E+06 - - - -0.9855 - 3.877 0.586 - 207.9 1 2 0 -0.0025 22 0 0 0 1.86E+07 1.30E+07 - - - 4.7692 1 221125_WJC_METTL3_EV_vs_WT_F08.16547.16547.3 2.06E-08 23/96 K.LGHPEALSAGTGSPQPPSFTYAQQR.E "sp|Q15942|ZYX_HUMAN,tr|H7C3D3|H7C3D3_HUMAN,tr|H0Y2Y8|H0Y2Y8_HUMAN" 3 2596.267 6.62 119465 16547 3 2596.266807 866.4296 Zyxin OS=Homo sapiens OX=9606 GN=ZYX PE=1 SV=1 6.75 2856.4 - 809060 - - - -0.0797 - 3.691 0.567 - 292.6 1 2 0 -0.0002 25 0 0 0 9.28E+06 1.40E+06 - - - 7.8658 0.9998 221125_WJC_METTL3_EV_vs_WT_F08.16548.16548.4 0.000652 21/126 K.SSQIGAVVSHQSSVIPDR[166.11]EYLR[166.11].K "sp|Q9NVS9|PNPO_HUMAN,tr|J3QQZ9|J3QQZ9_HUMAN,tr|J3QQV6|J3QQV6_HUMAN" 3 2447.2672 1.19 119466 16548 4 2447.265843 612.8241 Pyridoxine-5'-phosphate oxidase OS=Homo sapiens OX=9606 GN=PNPO PE=1 SV=1 6.47 2856.5 - 740596 - - - -0.5447 - 4.187 0.442 - 355.9 1 2 1 -0.0013 22 0 0 0 6.92E+06 5.80E+06 - - - 3.5413 0.9986 221125_WJC_METTL3_EV_vs_WT_F08.16551.16551.3 3.37E-09 Dec-76 T.SSTDGHSSYGLDSGFC[160.03]TISR[166.11].L sp|Q00587|BORG5_HUMAN 1 2142.9152 0.7 119469 16551 3 2142.911924 715.3123 Cdc42 effector protein 1 OS=Homo sapiens OX=9606 GN=CDC42EP1 PE=1 SV=1 5.19 2856.9 - 193816 - - - -1.5204 - 2.648 0.659 - 215.8 1 1 0 -0.0033 20 0 0 0 1.77E+06 2.53E+06 - - - 8.2488 0.9999 221125_WJC_METTL3_EV_vs_WT_F08.16557.16557.4 0.000349 12/108 R.GLLQDDAHPTLVTYADHSK[136.11].L "sp|Q86U44|MTA70_HUMAN,tr|F5H6D8|F5H6D8_HUMAN,tr|H0YFV6|H0YFV6_HUMAN,tr|B4DTN4|B4DTN4_HUMAN" 4 2088.0367 0.03 119473 16557 4 2088.034733 523.0165 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 5.13 2857.6 - 1.61E+06 - - - -0.9578 - 2.493 0.454 - 136.1 1 2 0 -0.002 19 0 0 0 1.48E+06 5.51E+07 - - - 3.4861 1 221125_WJC_METTL3_EV_vs_WT_F08.16561.16561.3 5.84E-08 23/96 K.C[160.03]SLQAAAILDANDAHQTETSSSQVK[136.11].D sp|Q9UHB9|SRP68_HUMAN 1 2652.2541 1.12 119477 16561 3 2652.249023 885.092 Signal recognition particle subunit SRP68 OS=Homo sapiens OX=9606 GN=SRP68 PE=1 SV=2 4.54 2858.1 - 620303 - - - -1.904 - 5.075 0.658 - 611 1 2 0 -0.005 25 0 0 0 7.94E+06 7.09E+06 - - - 9.6116 0.9999 221125_WJC_METTL3_EV_vs_WT_F08.16562.16562.4 0.00116 13/84 R.STSHK[136.11]PDEIYGMIER[166.11].L sp|Q86U44|MTA70_HUMAN 1 1779.8581 0.33 119478 16562 4 1779.856914 445.9718 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 5.42 2858.2 - 604704 - - - -0.6405 - 1.773 0.456 - 91.9 1 2 0 -0.0011 15 0 0 0 4.01E+06 1.22E+07 - - - 3.3996 0.9554 221125_WJC_METTL3_EV_vs_WT_F08.16564.16564.4 8.04E-05 23/120 F.AATATANQIPIISAEHLTSHK.Y "sp|Q9NR56|MBNL1_HUMAN,tr|Q86VM6|Q86VM6_HUMAN,tr|A0A0A0MQX8|A0A0A0MQX8_HUMAN" 3 2173.1491 1.75 119480 16564 4 2173.150334 544.2946 Muscleblind-like protein 1 OS=Homo sapiens OX=9606 GN=MBNL1 PE=1 SV=2 6.96 2858.5 - 580266 - - - 0.5536 - 3.394 0.327 - 306.5 1 1 0 0.0012 21 0 0 0 3.12E+07 1.78E+07 - - - 2.4759 0.9968 221125_WJC_METTL3_EV_vs_WT_F08.16567.16567.4 0.00303 Dec-90 R.TRRDEPTGEVLSLVGK.L "sp|O75643|U520_HUMAN,tr|A0A494C1A5|A0A494C1A5_HUMAN" 2 1755.9479 1.73 119483 16567 4 1755.946773 439.9943 U5 small nuclear ribonucleoprotein 200 kDa helicase OS=Homo sapiens OX=9606 GN=SNRNP200 PE=1 SV=2 5.85 2858.9 - 146852 - - - -0.6487 - 1.864 0.311 - 96.4 1 2 1 -0.0011 16 0 0 0 4.64E+06 2.69E+06 - - - 2.152 0.9997 221125_WJC_METTL3_EV_vs_WT_F08.16570.16570.4 0.00312 12/132 K.GVTIPYR[166.11]PK[136.11]PSSSPVIFAGGQDR[166.11].Y "sp|Q15366|PCBP2_HUMAN,tr|H3BSS4|H3BSS4_HUMAN" 2 2456.317 0.88 119484 16570 4 2456.317049 615.0865 Poly(rC)-binding protein 2 OS=Homo sapiens OX=9606 GN=PCBP2 PE=1 SV=1 9.99 2859.3 - 2.65E+06 - - - 0.0065 - 1.936 0.36 - 70.2 1 2 0 0 23 0 0 0 1.95E+07 2.21E+07 - - - 2.5735 1 221125_WJC_METTL3_EV_vs_WT_F08.16572.16572.3 2.38E-07 22/80 K.YQGDGIVEDEEETMENNEEK[136.11]K[136.11].D "sp|Q9NYF8|BCLF1_HUMAN,tr|H0YF63|H0YF63_HUMAN,tr|E9PK91|E9PK91_HUMAN,tr|H0YF14|H0YF14_HUMAN" 4 2501.0723 2.37 119486 16572 3 2501.070412 834.698 Bcl-2-associated transcription factor 1 OS=Homo sapiens OX=9606 GN=BCLAF1 PE=1 SV=2 3.89 2859.5 - 6.63E+06 - - - -0.7385 - 4.252 0.72 - 466.3 1 2 0 -0.0018 21 0 0 0 1.54E+08 6.49E+07 - - - 10.0368 0.9997 221125_WJC_METTL3_EV_vs_WT_F08.16574.16574.3 2.77E-08 24/52 K.RKQELAETLANLER.Q sp|Q9HAF1|EAF6_HUMAN 1 1669.9111 1.39 119488 16574 3 1669.916549 557.6443 Chromatin modification-related protein MEAF6 OS=Homo sapiens OX=9606 GN=MEAF6 PE=1 SV=1 6.23 2859.7 - 1.03E+06 - - - 3.2439 - 3.468 0.542 - 951.3 1 2 1 0.0054 14 0 0 0 2.44E+07 1.76E+07 - - - 7.8861 0.9999 221125_WJC_METTL3_EV_vs_WT_F08.16577.16577.4 1.20E-08 18/108 R.DGSAFEDGLR[166.11]HPFIVNHPK[136.11].V "sp|P55265|DSRAD_HUMAN,tr|A0A3B3IRQ9|A0A3B3IRQ9_HUMAN,tr|A0A7P0Z4K3|A0A7P0Z4K3_HUMAN,tr|A0A7P0Z4F9|A0A7P0Z4F9_HUMAN" 4 2153.0773 0.77 119491 16577 4 2153.076655 539.2766 Double-stranded RNA-specific adenosine deaminase OS=Homo sapiens OX=9606 GN=ADAR PE=1 SV=4 6 2860 - 681798 - - - -0.3028 - 3.486 0.609 - 226.2 1 2 1 -0.0007 19 0 0 0 5.55E+06 7.17E+06 - - - 4.949 0.9999 221125_WJC_METTL3_EV_vs_WT_F08.16580.16580.3 2.37E-08 15/72 K.QGEDNSTAQDTEELEK[136.11]EIR[166.11].E "sp|Q86UE4|LYRIC_HUMAN,tr|E5RJU9|E5RJU9_HUMAN" 2 2209.0101 1.41 119494 16580 3 2209.006848 737.344 Protein LYRIC OS=Homo sapiens OX=9606 GN=MTDH PE=1 SV=2 4 2860.4 - 315618 - - - -1.4875 - 3.299 0.611 - 375.5 1 2 1 -0.0033 19 0 0 0 4.04E+06 2.87E+06 - - - 8.2836 0.9996 221125_WJC_METTL3_EV_vs_WT_F08.16581.16581.4 8.27E-05 15/78 K.RKQELAETLANLER.Q sp|Q9HAF1|EAF6_HUMAN 1 1669.9111 1.73 119495 16581 4 1669.912933 418.4851 Chromatin modification-related protein MEAF6 OS=Homo sapiens OX=9606 GN=MEAF6 PE=1 SV=1 6.23 2860.5 - 243963 - - - 1.0785 - 2.76 0.407 - 273.9 1 2 1 0.0018 14 0 0 0 4.89E+06 2.82E+06 - - - 3.1375 1 221125_WJC_METTL3_EV_vs_WT_F08.16582.16582.3 1.62E-09 27/96 R.DK[136.11]LAQQQAAAAAAAAAAASQQGSAK[136.11].N "sp|Q9BZK7|TBL1R_HUMAN,tr|A0A1B0GUU2|A0A1B0GUU2_HUMAN,tr|C9IYU9|C9IYU9_HUMAN,tr|C9JCK0|C9JCK0_HUMAN,tr|A0A0D9SF63|A0A0D9SF63_HUMAN,tr|C9JBN1|C9JBN1_HUMAN,tr|C9JLJ1|C9JLJ1_HUMAN,tr|A0A0D9SF25|A0A0D9SF25_HUMAN" 8 2313.2008 1.74 119496 16582 3 2313.202664 772.0742 F-box-like\WD repeat-containing protein TBL1XR1 OS=Homo sapiens OX=9606 GN=TBL1XR1 PE=1 SV=1 8.59 2860.7 - 226260 - - - 0.8119 - 5.04 0.626 - 892.5 1 2 1 0.0019 25 0 0 0 3.50E+07 2.01E+07 - - - 9.2398 0.8466 221125_WJC_METTL3_EV_vs_WT_F08.16586.16586.3 5.12E-05 20/100 R.STSSFSC[160.03]LSRHGGGGGGFGGGGFGSR.S sp|P35908|K22E_HUMAN 1 2432.0676 -1 119498 16586 3 2433.052498 811.6965 "Keratin, type II cytoskeletal 2 epidermal OS=Homo sapiens OX=9606 GN=KRT2 PE=1 SV=2" 10.35 2861.2 - 3.03E+06 - - - 404.962 - 3.584 0.564 - 369.3 1 2 1 0.9849 26 0 0 0 0.00E+00 0.00E+00 - - - 7.4919 0.9998 221125_WJC_METTL3_EV_vs_WT_F08.16589.16589.3 4.53E-06 19/40 K.FAAQELIEVK[136.11]R[166.11].G "sp|Q86U44|MTA70_HUMAN,tr|F5H6D8|F5H6D8_HUMAN,tr|H0YFV6|H0YFV6_HUMAN,tr|B4DTN4|B4DTN4_HUMAN" 4 1320.7521 0 119501 16589 3 1320.751254 441.258 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 6.14 2861.5 - 1.96E+06 - - - -0.6072 - 2.807 0.282 - 333.3 1 2 0 -0.0008 11 0 0 0 1.70E+05 4.81E+07 - - - 4.6159 1 221125_WJC_METTL3_EV_vs_WT_F08.16590.16590.3 7.56E-13 36/96 R.DKLAQQQAAAAAAAAAAASQQGSAK.N "sp|Q9BZK7|TBL1R_HUMAN,tr|A0A1B0GUU2|A0A1B0GUU2_HUMAN,tr|C9IYU9|C9IYU9_HUMAN,tr|C9JCK0|C9JCK0_HUMAN,tr|A0A0D9SF63|A0A0D9SF63_HUMAN,tr|C9JBN1|C9JBN1_HUMAN,tr|C9JLJ1|C9JLJ1_HUMAN,tr|A0A0D9SF25|A0A0D9SF25_HUMAN" 8 2297.1724 1.74 119502 16590 3 2297.174938 766.7314 F-box-like\WD repeat-containing protein TBL1XR1 OS=Homo sapiens OX=9606 GN=TBL1XR1 PE=1 SV=1 8.59 2861.6 - 1.68E+06 - - - 1.1109 - 5.593 0.617 - 1988.9 1 2 1 0.0026 25 0 0 0 3.50E+07 2.01E+07 - - - 9.3788 0.9997 221125_WJC_METTL3_EV_vs_WT_F08.16592.16592.4 2.15E-07 18/138 R.GIDSEGHAANFVETEQIVHYNGSK.A "sp|Q9NTJ5|SAC1_HUMAN,tr|E9PGZ4|E9PGZ4_HUMAN,tr|A0A5F9ZHN7|A0A5F9ZHN7_HUMAN,tr|F8WDN7|F8WDN7_HUMAN" 4 2601.2096 2.39 119504 16592 4 2601.217004 651.3097 Phosphatidylinositol-3-phosphatase SAC1 OS=Homo sapiens OX=9606 GN=SACM1L PE=1 SV=2 4.8 2861.8 - 1.01E+06 - - - 2.8621 - 3.491 0.404 - 188.8 1 2 0 0.0074 24 0 0 0 2.10E+07 8.78E+06 - - - 3.1416 0.9999 221125_WJC_METTL3_EV_vs_WT_F08.16593.16593.3 7.90E-07 16/52 K.NKLEGLEDALQKAK.Q "sp|P48668|K2C6C_HUMAN,sp|P04259|K2C6B_HUMAN,sp|P02538|K2C6A_HUMAN" 3 1555.857 6.68 119505 16593 3 1555.856243 519.6263 "Keratin, type II cytoskeletal 6C OS=Homo sapiens OX=9606 GN=KRT6C PE=1 SV=3" 6.18 2862 - 395209 - - - -0.4686 - 2.619 0.548 - 207.5 1 2 2 -0.0007 14 0 0 0 2.86E+06 4.28E+05 - - - 7.2081 0.9983 221125_WJC_METTL3_EV_vs_WT_F08.16598.16598.4 4.85E-12 26/120 F.AATATANQIPIISAEHLTSHK[136.11].Y "sp|Q9NR56|MBNL1_HUMAN,tr|Q86VM6|Q86VM6_HUMAN,tr|A0A0A0MQX8|A0A0A0MQX8_HUMAN" 3 2181.1633 1.75 119508 16598 4 2181.163552 546.2981 Muscleblind-like protein 1 OS=Homo sapiens OX=9606 GN=MBNL1 PE=1 SV=2 6.96 2862.6 - 1.12E+06 - - - 0.1013 - 4.454 0.588 - 398.8 1 1 0 0.0002 21 0 0 0 3.11E+07 1.78E+07 - - - 4.8378 0.9996 221125_WJC_METTL3_EV_vs_WT_F08.16603.16603.3 5.13E-07 Dec-72 K.QTIDNSQGAYQEAFDISKK.E sp|P27348|1433T_HUMAN 1 2142.0229 0.88 119513 16603 3 2142.030253 715.0149 14-3-3 protein theta OS=Homo sapiens OX=9606 GN=YWHAQ PE=1 SV=1 4.56 2863.2 - 561954 - - - 3.4201 - 2.637 0.413 - 153.8 1 2 0 0.0073 19 0 0 0 5.92E+06 6.75E+06 - - - 5.5247 1 221125_WJC_METTL3_EV_vs_WT_F08.16604.16604.3 2.69E-09 14/80 R.C[160.03]ESAPGC[160.03]GVWQRPVIDNPNYK.G "sp|P27824|CALX_HUMAN,tr|A0A7P0T937|A0A7P0T937_HUMAN,tr|A0A7P0T840|A0A7P0T840_HUMAN,tr|A0A7P0TB65|A0A7P0TB65_HUMAN,tr|A0A7P0TAE9|A0A7P0TAE9_HUMAN,tr|D6RGY2|D6RGY2_HUMAN,tr|A0A7P0T8G1|A0A7P0T8G1_HUMAN,tr|A0A7P0Z4D6|A0A7P0Z4D6_HUMAN,tr|A0A7P0Z484|A0A7P0Z484_HUMAN,tr|A0A7P0TAR9|A0A7P0TAR9_HUMAN,tr|A0A7P0T9L0|A0A7P0T9L0_HUMAN" 11 2446.1158 1.48 119514 16604 3 2446.114746 816.3792 Calnexin OS=Homo sapiens OX=9606 GN=CANX PE=1 SV=2 6.05 2863.4 - 533236 - - - -0.4305 - 2.655 0.473 - 151.2 1 2 0 -0.0011 21 0 0 0 1.04E+07 7.01E+06 - - - 6.1542 1 221125_WJC_METTL3_EV_vs_WT_F08.16609.16609.3 4.42E-17 26/88 K.ER[166.11]PTPSLNNNC[160.03]TTSEDSLVLYNR[166.11].V "sp|P07814|SYEP_HUMAN,tr|V9GYZ6|V9GYZ6_HUMAN" 2 2699.2724 0.87 119517 16609 3 2699.273493 900.7647 Bifunctional glutamate\proline--tRNA ligase OS=Homo sapiens OX=9606 GN=EPRS1 PE=1 SV=5 4.68 2864 - 1.37E+06 - - - 0.4057 - 4.63 0.764 - 873.7 1 2 0 0.0011 23 0 0 0 4.07E+07 4.67E+07 - - - 10.6528 1 221125_WJC_METTL3_EV_vs_WT_F08.16610.16610.3 1.51E-12 21/88 K.ERPTPSLNNNC[160.03]TTSEDSLVLYNR.V "sp|P07814|SYEP_HUMAN,tr|V9GYZ6|V9GYZ6_HUMAN" 2 2679.2559 0.87 119518 16610 3 2679.259082 894.0926 Bifunctional glutamate\proline--tRNA ligase OS=Homo sapiens OX=9606 GN=EPRS1 PE=1 SV=5 4.68 2864.2 - 1.07E+06 - - - 1.2033 - 4.096 0.71 - 586.6 1 2 0 0.0032 23 0 0 0 4.07E+07 4.67E+07 - - - 9.7627 0.9997 221125_WJC_METTL3_EV_vs_WT_F08.16612.16612.4 1.45E-05 22/144 R.DKLAQQQAAAAAAAAAAASQQGSAK.N "sp|Q9BZK7|TBL1R_HUMAN,tr|A0A1B0GUU2|A0A1B0GUU2_HUMAN,tr|C9IYU9|C9IYU9_HUMAN,tr|C9JCK0|C9JCK0_HUMAN,tr|A0A0D9SF63|A0A0D9SF63_HUMAN,tr|C9JBN1|C9JBN1_HUMAN,tr|C9JLJ1|C9JLJ1_HUMAN,tr|A0A0D9SF25|A0A0D9SF25_HUMAN" 8 2297.1724 2.24 119520 16612 4 2297.177777 575.3004 F-box-like\WD repeat-containing protein TBL1XR1 OS=Homo sapiens OX=9606 GN=TBL1XR1 PE=1 SV=1 8.59 2864.4 - 695303 - - - 2.3468 - 3.967 0.491 - 352.6 1 2 1 0.0054 25 0 0 0 4.86E+06 2.17E+06 - - - 3.9365 1 221125_WJC_METTL3_EV_vs_WT_F08.16614.16614.3 1.30E-12 26/108 K.QNPSLPAPQTLAGGNPETAQPHAGTLPR[166.11].P "sp|Q68EM7|RHG17_HUMAN,tr|I3L3P1|I3L3P1_HUMAN,tr|I3L4Y5|I3L4Y5_HUMAN,tr|I3L460|I3L460_HUMAN" 4 2829.4397 2.22 119522 16614 3 2829.444595 944.1539 Rho GTPase-activating protein 17 OS=Homo sapiens OX=9606 GN=ARHGAP17 PE=1 SV=1 6.75 2864.6 - 467148 - - - 1.7215 - 4.318 0.684 - 526.4 1 1 0 0.0049 28 0 0 0 1.13E+07 5.07E+06 - - - 9.5299 1 221125_WJC_METTL3_EV_vs_WT_F08.16615.16615.3 2.37E-07 17/84 R.R[166.11]AELVC[160.03]LNNTEISENSSDLSQK[136.11].L sp|Q9P0K7|RAI14_HUMAN 1 2524.2194 1.27 119523 16615 3 2524.219736 842.4137 Ankycorbin OS=Homo sapiens OX=9606 GN=RAI14 PE=1 SV=2 4.41 2864.8 - 453392 - - - 0.1268 - 3.699 0.609 - 332 1 2 0 0.0003 22 0 0 0 2.85E+06 2.24E+06 - - - 8.4309 0.9995 221125_WJC_METTL3_EV_vs_WT_F08.16620.16620.4 0.000473 13/78 K.R[166.11]K[136.11]QELAETLANLER[166.11].Q sp|Q9HAF1|EAF6_HUMAN 1 1697.9419 1.73 119528 16620 4 1697.944377 425.4927 Chromatin modification-related protein MEAF6 OS=Homo sapiens OX=9606 GN=MEAF6 PE=1 SV=1 6.23 2865.4 - 257330 - - - 1.4753 - 2.654 0.416 - 202.2 1 2 1 0.0025 14 0 0 0 4.89E+06 2.82E+06 - - - 3.2014 0.9999 221125_WJC_METTL3_EV_vs_WT_F08.16626.16626.3 1.69E-05 22/52 K.R[166.11]K[136.11]QELAETLANLER[166.11].Q sp|Q9HAF1|EAF6_HUMAN 1 1697.9419 1.45 119532 16626 3 1697.94474 566.9879 Chromatin modification-related protein MEAF6 OS=Homo sapiens OX=9606 GN=MEAF6 PE=1 SV=1 6.23 2866.1 - 807204 - - - 1.6891 - 3.752 0.478 - 780.4 1 2 1 0.0029 14 0 0 0 2.44E+07 1.68E+07 - - - 7.3825 1 221125_WJC_METTL3_EV_vs_WT_F08.16627.16627.3 0.00048 Oct-80 R.C[160.03]ESAPGC[160.03]GVWQR[166.11]PVIDNPNYK[136.11].G "sp|P27824|CALX_HUMAN,tr|A0A7P0T937|A0A7P0T937_HUMAN,tr|A0A7P0T840|A0A7P0T840_HUMAN,tr|A0A7P0TB65|A0A7P0TB65_HUMAN,tr|A0A7P0TAE9|A0A7P0TAE9_HUMAN,tr|D6RGY2|D6RGY2_HUMAN,tr|A0A7P0T8G1|A0A7P0T8G1_HUMAN,tr|A0A7P0Z4D6|A0A7P0Z4D6_HUMAN,tr|A0A7P0Z484|A0A7P0Z484_HUMAN,tr|A0A7P0TAR9|A0A7P0TAR9_HUMAN,tr|A0A7P0T9L0|A0A7P0T9L0_HUMAN" 11 2464.1383 1.85 119533 16627 3 2464.139345 822.3867 Calnexin OS=Homo sapiens OX=9606 GN=CANX PE=1 SV=2 6.05 2866.2 - 702178 - - - 0.4367 - 2.179 0.525 - 88.7 1 2 0 0.0011 21 0 0 0 1.27E+07 6.86E+06 - - - 6.2602 1 221125_WJC_METTL3_EV_vs_WT_F08.16628.16628.3 1.31E-12 18/60 K.DTFEHDPSESIDEFNK.S "sp|Q9NYF8|BCLF1_HUMAN,tr|E9PKI6|E9PKI6_HUMAN,tr|A0A1W2PQ43|A0A1W2PQ43_HUMAN,tr|E9PK91|E9PK91_HUMAN,tr|E9PJA7|E9PJA7_HUMAN,tr|E9PK09|E9PK09_HUMAN,tr|E9PQN2|E9PQN2_HUMAN" 7 1908.8014 2.89 119534 16628 3 1908.80497 637.2744 Bcl-2-associated transcription factor 1 OS=Homo sapiens OX=9606 GN=BCLAF1 PE=1 SV=2 4.01 2866.4 - 675686 - - - 1.8876 - 3.331 0.726 - 519.3 1 2 0 0.0036 16 0 0 0 9.33E+06 3.23E+06 - - - 9.7206 0.9999 221125_WJC_METTL3_EV_vs_WT_F08.16629.16629.4 5.63E-08 20/84 K.KSDEC[160.03]KAEIELFVNR.L sp|Q99805|TM9S2_HUMAN 1 1836.904 1.34 119535 16629 4 1836.906927 460.2333 Transmembrane 9 superfamily member 2 OS=Homo sapiens OX=9606 GN=TM9SF2 PE=1 SV=1 4.87 2866.5 - 642896 - - - 1.5945 - 3.314 0.59 - 362 1 2 1 0.0029 15 0 0 0 8.22E+06 6.15E+06 - - - 4.7893 0.9999 221125_WJC_METTL3_EV_vs_WT_F08.16630.16630.3 5.97E-11 15/72 K.QTIDNSQGAYQEAFDISK[136.11]K[136.11].E sp|P27348|1433T_HUMAN 1 2158.0513 0.87 119536 16630 3 2158.058875 720.3577 14-3-3 protein theta OS=Homo sapiens OX=9606 GN=YWHAQ PE=1 SV=1 4.56 2866.6 - 486174 - - - 3.4976 - 3.076 0.625 - 212 1 2 0 0.0075 19 0 0 0 5.92E+06 6.84E+06 - - - 8.2666 1 221125_WJC_METTL3_EV_vs_WT_F08.16631.16631.3 1.08E-09 18/56 K.K[136.11]SDEC[160.03]K[136.11]AEIELFVNR[166.11].L sp|Q99805|TM9S2_HUMAN 1 1862.9407 1.54 119537 16631 3 1862.947982 621.9875 Transmembrane 9 superfamily member 2 OS=Homo sapiens OX=9606 GN=TM9SF2 PE=1 SV=1 4.87 2866.8 - 378991 - - - 3.9261 - 3.412 0.661 - 521.2 1 2 1 0.0073 15 0 0 0 6.22E+06 4.04E+06 - - - 9.1099 0.9999 221125_WJC_METTL3_EV_vs_WT_F08.16638.16638.4 2.49E-07 20/138 R.GIDSEGHAANFVETEQIVHYNGSK[136.11].A "sp|Q9NTJ5|SAC1_HUMAN,tr|E9PGZ4|E9PGZ4_HUMAN,tr|A0A5F9ZHN7|A0A5F9ZHN7_HUMAN,tr|F8WDN7|F8WDN7_HUMAN" 4 2609.2238 2.39 119542 16638 4 2609.229432 653.3132 Phosphatidylinositol-3-phosphatase SAC1 OS=Homo sapiens OX=9606 GN=SACM1L PE=1 SV=2 4.8 2867.7 - 911113 - - - 2.1742 - 3.812 0.509 - 259.6 1 2 0 0.0057 24 0 0 0 2.04E+07 8.51E+06 - - - 4.0843 0.9997 221125_WJC_METTL3_EV_vs_WT_F08.16639.16639.4 1.88E-06 14/84 K.K[136.11]SDEC[160.03]K[136.11]AEIELFVNR[166.11].L sp|Q99805|TM9S2_HUMAN 1 1862.9407 1.36 119543 16639 4 1862.943703 466.7424 Transmembrane 9 superfamily member 2 OS=Homo sapiens OX=9606 GN=TM9SF2 PE=1 SV=1 4.87 2867.8 - 599420 - - - 1.6291 - 2.434 0.454 - 162.2 1 2 1 0.003 15 0 0 0 8.39E+06 6.15E+06 - - - 3.4951 0.9714 221125_WJC_METTL3_EV_vs_WT_F08.16641.16641.4 0.000606 20/90 R.VREEVPLELVEAHVKK.V sp|Q92922|SMRC1_HUMAN 1 1874.0625 1.52 119545 16641 4 1874.0736 469.5229 SWI\SNF complex subunit SMARCC1 OS=Homo sapiens OX=9606 GN=SMARCC1 PE=1 SV=3 5.57 2868.1 - 385152 - - - 5.8973 - 2.537 0.351 - 278.7 1 2 1 0.0111 16 0 0 0 3.80E+06 2.50E+06 - - - 2.606 0.9999 221125_WJC_METTL3_EV_vs_WT_F08.16644.16644.4 5.51E-08 12/114 R.HIGKPLLGGPFSLTTHTGER.K "sp|O75880|SCO1_HUMAN,tr|J3QL56|J3QL56_HUMAN" 2 2117.1382 1.37 119548 16644 4 2117.143282 530.2918 "Protein SCO1 homolog, mitochondrial OS=Homo sapiens OX=9606 GN=SCO1 PE=1 SV=1" 8.76 2868.5 - 204554 - - - 2.4136 - 2.662 0.523 - 92.2 1 2 0 0.0051 20 0 0 0 2.48E+06 1.81E+06 - - - 4.1041 1 221125_WJC_METTL3_EV_vs_WT_F08.16653.16653.3 1.21E-12 16/56 K.KSDEC[160.03]KAEIELFVNR.L sp|Q99805|TM9S2_HUMAN 1 1836.904 1.54 119555 16653 3 1836.9128 613.3086 Transmembrane 9 superfamily member 2 OS=Homo sapiens OX=9606 GN=TM9SF2 PE=1 SV=1 4.87 2869.7 - 391350 - - - 4.7918 - 3.261 0.646 - 440.4 1 2 1 0.0088 15 0 0 0 6.22E+06 4.04E+06 - - - 8.8242 0.7937 221125_WJC_METTL3_EV_vs_WT_F08.16654.16654.3 0.0264 14/76 F.GQSPFSQPPAPPHQNTFPPR.S sp|Q96I24|FUBP3_HUMAN 1 2186.0657 1 119556 16654 3 2186.079679 729.6959 Far upstream element-binding protein 3 OS=Homo sapiens OX=9606 GN=FUBP3 PE=1 SV=2 9.76 2869.8 - 253647 - - - 6.3781 - 2.821 0.418 - 122.4 1 1 0 0.0139 20 0 0 0 1.31E+07 1.31E+07 - - - 5.7124 0.9923 221125_WJC_METTL3_EV_vs_WT_F08.16670.16670.3 0.00704 14/92 A.SESSGIPERPC[160.03]VLTGTPESIEQAK.R sp|Q96I24|FUBP3_HUMAN 1 2571.2486 3.06 119568 16670 3 2571.250393 858.0902 Far upstream element-binding protein 3 OS=Homo sapiens OX=9606 GN=FUBP3 PE=1 SV=2 4.49 2871.8 - 276378 - - - 0.679 - 2.387 0.442 - 113.9 1 1 0 0.0017 24 0 0 0 2.74E+07 8.97E+06 - - - 5.4881 1 221125_WJC_METTL3_EV_vs_WT_F08.16674.16674.4 3.46E-09 18/180 R.GAPAAAAAAAPPPTPAPPPPPAPVAAAAPAR[166.11].A sp|Q6SPF0|SAMD1_HUMAN 1 2671.4474 3.72 119572 16674 4 2671.447466 668.8691 Sterile alpha motif domain-containing protein 1 OS=Homo sapiens OX=9606 GN=SAMD1 PE=1 SV=1 9.75 2872.3 - 153526 - - - 0.0337 - 4.027 0.535 - 195.6 1 2 0 0.0001 31 0 0 0 1.47E+07 3.95E+06 - - - 4.306 0.9998 221125_WJC_METTL3_EV_vs_WT_F08.16679.16679.4 0.00068 24/180 R.GAPAAAAAAAPPPTPAPPPPPAPVAAAAPAR.A sp|Q6SPF0|SAMD1_HUMAN 1 2661.4391 3.75 119576 16679 4 2661.448963 666.3671 Sterile alpha motif domain-containing protein 1 OS=Homo sapiens OX=9606 GN=SAMD1 PE=1 SV=1 9.75 2873.1 - 320077 - - - 3.7036 - 4.669 0.469 - 383.2 1 2 0 0.0099 31 0 0 0 1.50E+07 3.99E+06 - - - 3.7738 0.998 221125_WJC_METTL3_EV_vs_WT_F08.16682.16682.4 0.0393 Sep-84 K.YQEEFEHFQQELDKK.K sp|P49257|LMAN1_HUMAN 1 1996.9167 1.58 119578 16682 4 1996.924994 500.2364 Protein ERGIC-53 OS=Homo sapiens OX=9606 GN=LMAN1 PE=1 SV=2 4.57 2873.4 - 539315 - - - 4.1679 - 2.025 0.365 - 74.3 1 2 0 0.0083 15 0 0 0 1.67E+07 1.06E+07 - - - 2.6531 0.9872 221125_WJC_METTL3_EV_vs_WT_F08.16685.16685.3 0.00739 10/108 V.PTAPTSGGPK[136.11]PSTASAVPELATDPELEK[136.11].K "sp|Q86U44|MTA70_HUMAN,tr|B4E349|B4E349_HUMAN,tr|F5H6D8|F5H6D8_HUMAN,tr|H0YFV6|H0YFV6_HUMAN,tr|B4DTN4|B4DTN4_HUMAN" 5 2763.4149 0.001 119581 16685 3 2763.417386 922.1456 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 4.41 2873.8 - 204619 - - - 0.892 - 2.399 0.403 - 48.4 1 1 0 0.0025 28 0 0 0 0.00E+00 5.25E+06 - - - 5.0455 0.9999 221125_WJC_METTL3_EV_vs_WT_F08.16692.16692.4 1.35E-05 Oct-84 K.YQEEFEHFQQELDK[136.11]K[136.11].K sp|P49257|LMAN1_HUMAN 1 2012.9451 1.86 119586 16692 4 2012.947757 504.2435 Protein ERGIC-53 OS=Homo sapiens OX=9606 GN=LMAN1 PE=1 SV=2 4.57 2874.7 - 658538 - - - 1.3344 - 2.004 0.483 - 82.5 1 2 0 0.0027 15 0 0 0 1.98E+07 1.07E+07 - - - 3.678 0.9994 221125_WJC_METTL3_EV_vs_WT_F08.16698.16698.4 0.529 22/114 K.LDK[136.11]SQIHDIVLVGGSTR[166.11]IPK[136.11].L "sp|P11142|HSP7C_HUMAN,tr|E9PNE6|E9PNE6_HUMAN,tr|A8K7Q2|A8K7Q2_HUMAN,tr|E9PKE3|E9PKE3_HUMAN,tr|E9PN89|E9PN89_HUMAN" 5 2201.2742 0.05 119592 16698 4 2201.283896 551.3258 Heat shock cognate 71 kDa protein OS=Homo sapiens OX=9606 GN=HSPA8 PE=1 SV=1 8.6 2875.5 - 479265 - - - 4.3947 - 4.484 0.557 - 288.3 1 2 2 0.0097 20 0 0 0 4.98E+05 9.35E+06 - - - 4.5731 0.9899 221125_WJC_METTL3_EV_vs_WT_F08.16699.16699.4 2.66E-09 22/114 R.IRDPNQGGKDITEEIMSGAR.T "sp|Q04637|IF4G1_HUMAN,tr|C9J2Z7|C9J2Z7_HUMAN,tr|E7EUU4|E7EUU4_HUMAN,tr|E9PGM1|E9PGM1_HUMAN,tr|C9J6B6|C9J6B6_HUMAN,tr|E7EX73|E7EX73_HUMAN,tr|C9K073|C9K073_HUMAN,tr|F8WCF2|F8WCF2_HUMAN,tr|C9JHW9|C9JHW9_HUMAN,tr|A0A7I2Y1C3|A0A7I2Y1C3_HUMAN,tr|C9JF13|C9JF13_HUMAN" 11 2186.075 1.12 119593 16699 4 2186.087933 547.526 Eukaryotic translation initiation factor 4 gamma 1 OS=Homo sapiens OX=9606 GN=EIF4G1 PE=1 SV=4 4.78 2875.7 - 464985 - - - 5.9252 - 3.831 0.404 - 315.7 1 2 2 0.013 20 0 0 0 6.28E+06 5.60E+06 - - - 3.1879 0.9997 221125_WJC_METTL3_EV_vs_WT_F08.16702.16702.4 5.13E-06 11/114 R.HIGK[136.11]PLLGGPFSLTTHTGER[166.11].K "sp|O75880|SCO1_HUMAN,tr|J3QL56|J3QL56_HUMAN" 2 2135.1606 1.18 119596 16702 4 2135.170003 534.7974 "Protein SCO1 homolog, mitochondrial OS=Homo sapiens OX=9606 GN=SCO1 PE=1 SV=1" 8.76 2876 - 184460 - - - 4.3842 - 2.319 0.509 - 50.7 1 2 0 0.0094 20 0 0 0 8.30E+06 7.03E+06 - - - 3.935 0.9996 221125_WJC_METTL3_EV_vs_WT_F08.16705.16705.4 3.75E-08 14/114 K.GTFDGDKLGDLKEEGDVMDK.T "sp|Q14671|PUM1_HUMAN,tr|Q5T1Z8|Q5T1Z8_HUMAN,tr|H0YEH2|H0YEH2_HUMAN,tr|Q5T1Z4|Q5T1Z4_HUMAN" 4 2167.9943 2.17 119597 16705 4 2168.002631 543.0059 Pumilio homolog 1 OS=Homo sapiens OX=9606 GN=PUM1 PE=1 SV=3 4.09 2876.5 - 1.01E+06 - - - 3.8293 - 3.258 0.565 - 137.2 1 2 2 0.0083 20 0 0 0 1.99E+07 9.18E+06 - - - 4.5363 1 221125_WJC_METTL3_EV_vs_WT_F08.16708.16708.3 1.48E-05 19/76 K.GTFDGDKLGDLKEEGDVMDK.T "sp|Q14671|PUM1_HUMAN,tr|Q5T1Z8|Q5T1Z8_HUMAN,tr|H0YEH2|H0YEH2_HUMAN,tr|Q5T1Z4|Q5T1Z4_HUMAN" 4 2167.9943 3.54 119600 16708 3 2168.001921 723.6721 Pumilio homolog 1 OS=Homo sapiens OX=9606 GN=PUM1 PE=1 SV=3 4.09 2876.8 - 375445 - - - 3.5019 - 4.223 0.648 - 476.7 1 2 2 0.0076 20 0 0 0 9.07E+06 2.57E+06 - - - 9.2573 1 221125_WJC_METTL3_EV_vs_WT_F08.16709.16709.4 6.91E-09 20/162 K.QNPSLPAPQTLAGGNPETAQPHAGTLPR.P "sp|Q68EM7|RHG17_HUMAN,tr|I3L3P1|I3L3P1_HUMAN,tr|I3L4Y5|I3L4Y5_HUMAN,tr|I3L460|I3L460_HUMAN" 4 2819.4315 3.17 119601 16709 4 2819.440423 705.8651 Rho GTPase-activating protein 17 OS=Homo sapiens OX=9606 GN=ARHGAP17 PE=1 SV=1 6.75 2877 - 237006 - - - 3.1811 - 3.339 0.634 - 164.4 1 1 0 0.009 28 0 0 0 2.98E+06 9.41E+05 - - - 5.1162 0.9995 221125_WJC_METTL3_EV_vs_WT_F08.16712.16712.4 3.27E-05 11/114 K.ASEAEAPDK[136.11]HGSASFVSLLK[136.11].S sp|Q9NXV6|CARF_HUMAN 1 2059.0557 1.24 119602 16712 4 2059.061432 515.7712 CDKN2A-interacting protein OS=Homo sapiens OX=9606 GN=CDKN2AIP PE=1 SV=3 5.45 2877.4 - 407092 - - - 2.7911 - 2.537 0.475 - 98.8 1 2 1 0.0057 20 0 0 0 1.08E+07 8.68E+06 - - - 3.6701 0.9995 221125_WJC_METTL3_EV_vs_WT_F08.16714.16714.4 1.38E-08 17/114 K.ASEAEAPDKHGSASFVSLLK.S sp|Q9NXV6|CARF_HUMAN 1 2043.0273 0.98 119604 16714 4 2043.035839 511.7641 CDKN2A-interacting protein OS=Homo sapiens OX=9606 GN=CDKN2AIP PE=1 SV=3 5.45 2877.6 - 461433 - - - 4.1874 - 3.221 0.573 - 273.6 1 2 1 0.0086 20 0 0 0 1.11E+07 1.13E+07 - - - 4.6021 0.9984 221125_WJC_METTL3_EV_vs_WT_F08.16715.16715.4 0.000243 14/126 R.SDDGVFHIGAAAQDKPSAEVLK.S "sp|Q6BDS2|URFB1_HUMAN,tr|H7C1J4|H7C1J4_HUMAN" 2 2254.123 0.94 119605 16715 4 2254.131803 564.538 UHRF1-binding protein 1 OS=Homo sapiens OX=9606 GN=UHRF1BP1 PE=1 SV=1 4.66 2877.8 - 396076 - - - 3.9159 - 2.312 0.363 - 84.5 1 2 0 0.0088 22 0 0 0 8.90E+06 9.50E+06 - - - 2.6573 0.9999 221125_WJC_METTL3_EV_vs_WT_F08.16716.16716.4 6.73E-06 15/126 R.SDDGVFHIGAAAQDK[136.11]PSAEVLK[136.11].S "sp|Q6BDS2|URFB1_HUMAN,tr|H7C1J4|H7C1J4_HUMAN" 2 2270.1514 0.93 119606 16716 4 2270.156844 568.5451 UHRF1-binding protein 1 OS=Homo sapiens OX=9606 GN=UHRF1BP1 PE=1 SV=1 4.66 2877.9 - 376813 - - - 2.4086 - 2.694 0.466 - 125.1 1 2 0 0.0055 22 0 0 0 8.81E+06 9.46E+06 - - - 3.6048 1 221125_WJC_METTL3_EV_vs_WT_F08.16725.16725.4 3.17E-06 12/126 K.VHNDAQSFDYDHDAFLGAEEAK.T sp|O43852|CALU_HUMAN 1 2478.0724 1.27 119613 16725 4 2478.076484 620.5254 Calumenin OS=Homo sapiens OX=9606 GN=CALU PE=1 SV=2 4.22 2879.1 - 185102 - - - 1.6493 - 2.274 0.522 - 66.4 1 2 0 0.0041 22 0 0 0 6.45E+06 5.06E+06 - - - 4.0372 1 221125_WJC_METTL3_EV_vs_WT_F08.16732.16732.3 4.16E-06 20/120 R.GAPAAAAAAAPPPTPAPPPPPAPVAAAAPAR.A sp|Q6SPF0|SAMD1_HUMAN 1 2661.4391 3.48 119617 16732 3 2661.444974 888.1536 Sterile alpha motif domain-containing protein 1 OS=Homo sapiens OX=9606 GN=SAMD1 PE=1 SV=1 9.75 2880 - 302331 - - - 2.2048 - 4.233 0.628 - 318.3 1 2 0 0.0059 31 0 0 0 5.08E+07 1.46E+07 - - - 8.8596 0.9717 221125_WJC_METTL3_EV_vs_WT_F08.16734.16734.3 0.568 13/56 R.NSKIEISELNRVIQR.L sp|P04264|K2C1_HUMAN 1 1798.0061 319.9 119618 16734 3 1798.011029 600.3426 "Keratin, type II cytoskeletal 1 OS=Homo sapiens OX=9606 GN=KRT1 PE=1 SV=6" 8.75 2880.3 - 597513 - - - 2.7442 - 2.006 0.223 - 203.4 1 2 2 0.0049 15 0 0 0 1.41E+07 4.42E+04 - - - 2.8414 0.9999 221125_WJC_METTL3_EV_vs_WT_F08.16742.16742.4 0.000228 14/180 K.TPAQLAGHMQTHLGGAAPPVPGDAPQPQPTC[160.03].- tr|I3L0M3|I3L0M3_HUMAN 1 3101.4811 - 119624 16742 4 3101.482552 776.3776 "MYC-associated zinc finger protein (Purine-binding transcription factor), isoform CRA_e OS=Homo sapiens OX=9606 GN=MAZ PE=1 SV=1" 5.9 2881.2 - 192529 - - - 0.4607 - 2.513 0.422 - 67.3 1 2 0 0.0014 31 0 0 0 - - - - - 3.1788 0.9973 221125_WJC_METTL3_EV_vs_WT_F08.16744.16744.4 5.76E-05 11/126 K.VHNDAQSFDYDHDAFLGAEEAK[136.11].T sp|O43852|CALU_HUMAN 1 2486.0866 1.27 119626 16744 4 2487.092818 622.5289 Calumenin OS=Homo sapiens OX=9606 GN=CALU PE=1 SV=2 4.22 2881.5 - 288741 - - - 404.7409 - 1.94 0.472 - 41.5 1 2 0 1.0062 22 0 0 0 6.45E+06 5.06E+06 - - - 3.2724 0.9999 221125_WJC_METTL3_EV_vs_WT_F08.16745.16745.4 1.41E-06 16/132 K.AADFQLHTHVNDGTEFGGSIYQK[136.11].V sp|Q9Y277|VDAC3_HUMAN 1 2542.1968 1.21 119627 16745 4 2542.20374 636.5565 Voltage-dependent anion-selective channel protein 3 OS=Homo sapiens OX=9606 GN=VDAC3 PE=1 SV=1 5.21 2881.6 - 286391 - - - 2.7236 - 3.31 0.519 - 144 1 2 0 0.0069 23 0 0 0 2.93E+07 2.43E+07 - - - 4.1293 0.9999 221125_WJC_METTL3_EV_vs_WT_F08.16748.16748.3 0.0027 16/120 K.TPAQLAGHMQTHLGGAAPPVPGDAPQPQPTC[160.03].- tr|I3L0M3|I3L0M3_HUMAN 1 3101.4811 - 119628 16748 3 3101.490909 1034.8343 "MYC-associated zinc finger protein (Purine-binding transcription factor), isoform CRA_e OS=Homo sapiens OX=9606 GN=MAZ PE=1 SV=1" 5.9 2882.1 - 183016 - - - 3.1553 - 2.99 0.567 - 96.6 1 2 0 0.0098 31 0 0 0 - - - - - 7.3786 0.9998 221125_WJC_METTL3_EV_vs_WT_F08.16749.16749.3 1.22E-07 14/72 R.DGNEVEPDDDHFSIGVGSR[166.11].L "sp|Q15633|TRBP2_HUMAN,tr|F8VSA1|F8VSA1_HUMAN,tr|H3BV98|H3BV98_HUMAN" 3 2053.8853 2.97 119629 16749 3 2053.894043 685.6357 RISC-loading complex subunit TARBP2 OS=Homo sapiens OX=9606 GN=TARBP2 PE=1 SV=3 3.96 2882.2 - 218803 - - - 4.2758 - 2.874 0.556 - 243.4 1 2 0 0.0088 19 0 0 0 7.71E+06 2.59E+06 - - - 7.3301 1 221125_WJC_METTL3_EV_vs_WT_F08.16751.16751.3 3.08E-09 9/104 K.EIEESKEPGVEDTEWSNTQTEEAIQTR.S "sp|Q99986|VRK1_HUMAN,tr|A0A7P0T838|A0A7P0T838_HUMAN,tr|A0A7P0TA16|A0A7P0TA16_HUMAN,tr|H0YJF7|H0YJF7_HUMAN,tr|A0A7P0T9T1|A0A7P0T9T1_HUMAN,tr|A0A7P0Z4A4|A0A7P0Z4A4_HUMAN,tr|A0A7P0T9E5|A0A7P0T9E5_HUMAN,tr|A0A7P0TBE4|A0A7P0TBE4_HUMAN,tr|A0A7P0TA65|A0A7P0TA65_HUMAN,tr|A0A7P0T824|A0A7P0T824_HUMAN,tr|A0A7P0TB15|A0A7P0TB15_HUMAN,tr|A0A7P0T952|A0A7P0T952_HUMAN" 12 3134.4164 0.32 119631 16751 3 3134.417419 1045.8127 Serine\threonine-protein kinase VRK1 OS=Homo sapiens OX=9606 GN=VRK1 PE=1 SV=1 3.93 2882.4 - 115834 - - - 0.3324 - 2.595 0.669 - 76.4 1 2 1 0.001 27 0 0 0 3.31E+06 1.04E+07 - - - 8.1923 1 221125_WJC_METTL3_EV_vs_WT_F08.16759.16759.4 1.53E-05 16/132 K.AADFQLHTHVNDGTEFGGSIYQK.V sp|Q9Y277|VDAC3_HUMAN 1 2534.1826 1.21 119635 16759 4 2534.183567 634.5529 Voltage-dependent anion-selective channel protein 3 OS=Homo sapiens OX=9606 GN=VDAC3 PE=1 SV=1 5.21 2883.7 - 580333 - - - 0.3753 - 3.368 0.467 - 157.5 1 2 0 0.001 23 0 0 0 2.93E+07 2.43E+07 - - - 3.6839 1 221125_WJC_METTL3_EV_vs_WT_F08.16760.16760.3 1.71E-08 14/104 K.EIEESK[136.11]EPGVEDTEWSNTQTEEAIQTR[166.11].S "sp|Q99986|VRK1_HUMAN,tr|A0A7P0T838|A0A7P0T838_HUMAN,tr|A0A7P0TA16|A0A7P0TA16_HUMAN,tr|H0YJF7|H0YJF7_HUMAN,tr|A0A7P0T9T1|A0A7P0T9T1_HUMAN,tr|A0A7P0Z4A4|A0A7P0Z4A4_HUMAN,tr|A0A7P0T9E5|A0A7P0T9E5_HUMAN,tr|A0A7P0TBE4|A0A7P0TBE4_HUMAN,tr|A0A7P0TA65|A0A7P0TA65_HUMAN,tr|A0A7P0T824|A0A7P0T824_HUMAN,tr|A0A7P0TB15|A0A7P0TB15_HUMAN,tr|A0A7P0T952|A0A7P0T952_HUMAN" 12 3152.4388 0.32 119636 16760 3 3152.439841 1051.8202 Serine\threonine-protein kinase VRK1 OS=Homo sapiens OX=9606 GN=VRK1 PE=1 SV=1 3.93 2883.8 - 404460 - - - 0.3153 - 3.28 0.637 - 199.2 1 2 1 0.001 27 0 0 0 3.31E+06 1.04E+07 - - - 8.3744 0.9968 221125_WJC_METTL3_EV_vs_WT_F08.16762.16762.4 0.000159 17/126 K.SKAEAESLYQSKYEELQITAGR.H sp|P04264|K2C1_HUMAN 1 2500.2445 1355.53 119638 16762 4 2500.258749 626.0684 "Keratin, type II cytoskeletal 1 OS=Homo sapiens OX=9606 GN=KRT1 PE=1 SV=6" 4.94 2884.1 - 536381 - - - 5.6798 - 3.377 0.488 - 147.7 1 2 2 0.0142 22 0 0 0 6.25E+07 4.61E+04 - - - 3.8678 0.9799 221125_WJC_METTL3_EV_vs_WT_F08.16773.16773.3 1.38E-05 11/100 K.QHGVNVSVNASATPFQQPSGYGSHGY.N "sp|Q14157|UBP2L_HUMAN,tr|F8W726|F8W726_HUMAN,tr|H7C2T8|H7C2T8_HUMAN,tr|H0Y5H6|H0Y5H6_HUMAN" 4 2688.2317 - 119645 16773 3 2688.238393 897.0845 Ubiquitin-associated protein 2-like OS=Homo sapiens OX=9606 GN=UBAP2L PE=1 SV=2 6.92 2885.4 - 264855 - - - 2.4931 - 2.431 0.442 - 69.6 1 1 0 0.0067 26 0 0 0 - - - - - 5.5097 1 221125_WJC_METTL3_EV_vs_WT_F08.16777.16777.3 2.64E-13 16/108 K.QNPSLPAPQTLAGGNPETAQPHAGTLPR.P "sp|Q68EM7|RHG17_HUMAN,tr|I3L3P1|I3L3P1_HUMAN,tr|I3L4Y5|I3L4Y5_HUMAN,tr|I3L460|I3L460_HUMAN" 4 2819.4315 2.71 119647 16777 3 2819.439303 940.8178 Rho GTPase-activating protein 17 OS=Homo sapiens OX=9606 GN=ARHGAP17 PE=1 SV=1 6.75 2886 - 206498 - - - 2.7839 - 3.408 0.682 - 149 1 1 0 0.0078 28 0 0 0 1.62E+07 5.97E+06 - - - 8.9623 1 221125_WJC_METTL3_EV_vs_WT_F08.16788.16788.3 2.70E-14 28/84 K.SKAEAESLYQSKYEELQITAGR.H sp|P04264|K2C1_HUMAN 1 2500.2445 999 119653 16788 3 2500.250777 834.4221 "Keratin, type II cytoskeletal 1 OS=Homo sapiens OX=9606 GN=KRT1 PE=1 SV=6" 4.94 2887.4 - 583892 - - - 2.4914 - 5.021 0.701 - 1165.6 1 2 2 0.0062 22 0 0 0 6.32E+06 0.00E+00 - - - 10.1794 0.9567 221125_WJC_METTL3_EV_vs_WT_F08.16790.16790.4 9.88E-06 16/96 K.LDK[136.11]AQIHDLVLVGGSTR[166.11].L "sp|P0DMV8|HS71A_HUMAN,sp|P0DMV9|HS71B_HUMAN,tr|V9GZ37|V9GZ37_HUMAN,tr|A0A0G2JIW1|A0A0G2JIW1_HUMAN" 4 1839.0333 0.1 119655 16790 4 1839.035474 460.7656 Heat shock 70 kDa protein 1A OS=Homo sapiens OX=9606 GN=HSPA1A PE=1 SV=1 6.75 2887.7 - 352560 - - - 1.1729 - 2.897 0.176 - 175.8 1 2 1 0.0022 17 0 0 0 8.58E+05 8.24E+06 - - - 1.1266 1 221125_WJC_METTL3_EV_vs_WT_F08.16791.16791.3 0.000858 Oct-88 K.AADFQLHTHVNDGTEFGGSIYQK.V sp|Q9Y277|VDAC3_HUMAN 1 2534.1826 1.42 119656 16791 3 2534.18006 845.7348 Voltage-dependent anion-selective channel protein 3 OS=Homo sapiens OX=9606 GN=VDAC3 PE=1 SV=1 5.21 2887.8 - 289268 - - - -1.0086 - 2.736 0.456 - 81.3 1 2 0 -0.0026 23 0 0 0 6.49E+06 4.58E+06 - - - 5.9844 0.9366 221125_WJC_METTL3_EV_vs_WT_F08.16793.16793.4 0.0407 Sep-96 K.DKPNRGEAQLVIPFSGK.G "sp|Q9H040|SPRTN_HUMAN,tr|B1AKT1|B1AKT1_HUMAN" 2 1854.9952 1.8 119658 16793 4 1854.995658 464.7561 DNA-dependent metalloprotease SPRTN OS=Homo sapiens OX=9606 GN=SPRTN PE=1 SV=2 8.59 2888.1 - 143010 - - - 0.2491 - 1.515 0.186 - 72.5 1 2 1 0.0005 17 0 0 0 4.39E+06 2.43E+06 - - - 0.989 0.9993 221125_WJC_METTL3_EV_vs_WT_F08.16795.16795.4 0.00166 15/84 R.STSHK[136.11]PDEIYGMIER[166.11].L sp|Q86U44|MTA70_HUMAN 1 1779.8581 0.08 119659 16795 4 1779.860047 445.9718 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 5.42 2888.4 - 452135 - - - 1.1198 - 2.433 0.309 - 163.7 1 2 0 0.002 15 0 0 0 2.30E+06 2.88E+07 - - - 2.2331 0.9999 221125_WJC_METTL3_EV_vs_WT_F08.16800.16800.3 1.10E-05 16/88 K.AADFQLHTHVNDGTEFGGSIYQK[136.11].V sp|Q9Y277|VDAC3_HUMAN 1 2542.1968 1.42 119663 16800 3 2542.193143 848.4062 Voltage-dependent anion-selective channel protein 3 OS=Homo sapiens OX=9606 GN=VDAC3 PE=1 SV=1 5.21 2889 - 378327 - - - -1.4448 - 2.519 0.471 - 108.5 1 2 0 -0.0037 23 0 0 0 6.49E+06 4.58E+06 - - - 5.9575 1 221125_WJC_METTL3_EV_vs_WT_F08.16803.16803.4 1.34E-06 15/132 K.HGEVC[160.03]PAGWK[136.11]PGSETIIPDPAGK[136.11].L sp|Q13162|PRDX4_HUMAN 1 2418.1973 0.64 119664 16803 4 2418.198055 605.5566 Peroxiredoxin-4 OS=Homo sapiens OX=9606 GN=PRDX4 PE=1 SV=1 5.45 2889.4 - 385729 - - - 0.3205 - 2.468 0.486 - 90.6 1 2 0 0.0008 23 0 0 0 1.65E+07 2.56E+07 - - - 3.7486 0.9999 221125_WJC_METTL3_EV_vs_WT_F08.16811.16811.3 7.23E-06 Sep-52 K.K[136.11]GPGEVAGTVTGQK[136.11].R "sp|Q86U44|MTA70_HUMAN,tr|F5H6D8|F5H6D8_HUMAN,tr|H0YFV6|H0YFV6_HUMAN,tr|B4DTN4|B4DTN4_HUMAN" 4 1343.738 0 119669 16811 3 1343.7405 448.9199 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 8.59 2890.5 - 214708 - - - 1.8761 - 2.086 0.476 - 77.1 1 2 0 0.0025 14 0 0 0 4.19E+04 8.97E+06 - - - 5.8002 1 221125_WJC_METTL3_EV_vs_WT_F08.16812.16812.4 3.76E-10 12/144 K.SNPSEVVEFTTC[160.03]PDKPGIPVKPSVK.G "sp|Q9Y2H6|FND3A_HUMAN,tr|G5E9X3|G5E9X3_HUMAN" 2 2711.384 0.93 119670 16812 4 2711.389236 678.8533 Fibronectin type-III domain-containing protein 3A OS=Homo sapiens OX=9606 GN=FNDC3A PE=1 SV=4 5.9 2890.6 - 378025 - - - 1.9245 - 2.74 0.571 - 67.9 1 2 0 0.0052 25 0 0 0 6.21E+06 6.67E+06 - - - 4.5152 0.9999 221125_WJC_METTL3_EV_vs_WT_F08.16813.16813.4 1.67E-08 15/108 R.SAFEEEGK[136.11]ETADITHALSK[136.11].L sp|Q15042|RB3GP_HUMAN 1 2078.0139 0.88 119671 16813 4 2078.009171 520.5107 Rab3 GTPase-activating protein catalytic subunit OS=Homo sapiens OX=9606 GN=RAB3GAP1 PE=1 SV=3 4.57 2890.7 - 339496 - - - -2.2656 - 3.016 0.557 - 156.4 1 2 1 -0.0047 19 0 0 0 1.07E+07 1.22E+07 - - - 4.4463 0.9996 221125_WJC_METTL3_EV_vs_WT_F08.16814.16814.4 0.000902 11/108 R.GLLQDDAHPTLVTYADHSK[136.11].L "sp|Q86U44|MTA70_HUMAN,tr|F5H6D8|F5H6D8_HUMAN,tr|H0YFV6|H0YFV6_HUMAN,tr|B4DTN4|B4DTN4_HUMAN" 4 2088.0367 0.47 119672 16814 4 2088.039788 523.0165 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 5.13 2890.9 - 269833 - - - 1.4631 - 2.199 0.348 - 104 1 2 0 0.0031 19 0 0 0 6.20E+06 1.32E+07 - - - 2.5207 0.9999 221125_WJC_METTL3_EV_vs_WT_F08.16816.16816.4 3.54E-06 13/72 R.C[160.03]ILPFDK[136.11]ETGFHR[166.11].G "sp|Q9GZT3|SLIRP_HUMAN,tr|H0YJW7|H0YJW7_HUMAN,tr|A0A087WUN7|A0A087WUN7_HUMAN,tr|G3V2S9|G3V2S9_HUMAN,tr|H0YJ40|H0YJ40_HUMAN,tr|G3V4X6|G3V4X6_HUMAN" 6 1636.8151 1.13 119674 16816 4 1636.816812 410.211 "SRA stem-loop-interacting RNA-binding protein, mitochondrial OS=Homo sapiens OX=9606 GN=SLIRP PE=1 SV=1" 6.74 2891.1 - 159221 - - - 1.0661 - 2.702 0.53 - 166.7 1 2 1 0.0017 13 0 0 0 5.88E+06 5.19E+06 - - - 4.2072 0.9767 221125_WJC_METTL3_EV_vs_WT_F08.16819.16819.4 0.00378 17/156 R.SLYGLGGSKRISIGGGSC[160.03]AISGGYGSR.A "sp|P48668|K2C6C_HUMAN,sp|P04259|K2C6B_HUMAN,sp|P02538|K2C6A_HUMAN" 3 2616.3078 999 119675 16819 4 2616.321653 655.0842 "Keratin, type II cytoskeletal 6C OS=Homo sapiens OX=9606 GN=KRT6C PE=1 SV=3" 9.78 2891.5 - 499754 - - - 5.2819 - 2.594 0.343 - 106.5 1 2 1 0.0138 27 0 0 0 7.32E+06 0.00E+00 - - - 2.5059 1 221125_WJC_METTL3_EV_vs_WT_F08.16821.16821.3 6.13E-10 20/88 R.YSTPHAFTFNTSSPSSEGSLSQR[166.11].Q "sp|P04049|RAF1_HUMAN,tr|H7C155|H7C155_HUMAN" 2 2497.1385 0.93 119677 16821 3 2497.139038 833.3868 RAF proto-oncogene serine\threonine-protein kinase OS=Homo sapiens OX=9606 GN=RAF1 PE=1 SV=1 6.75 2891.8 - 791444 - - - 0.209 - 3.581 0.627 - 297.7 1 2 0 0.0005 23 0 0 0 1.79E+07 1.92E+07 - - - 8.5229 0.9999 221125_WJC_METTL3_EV_vs_WT_F08.16822.16822.4 3.59E-08 17/108 R.SAFEEEGKETADITHALSK.L sp|Q15042|RB3GP_HUMAN 1 2061.9855 0.84 119678 16822 4 2061.989128 516.5036 Rab3 GTPase-activating protein catalytic subunit OS=Homo sapiens OX=9606 GN=RAB3GAP1 PE=1 SV=3 4.57 2891.9 - 513194 - - - 1.7697 - 2.962 0.546 - 162.9 1 2 1 0.0036 19 0 0 0 1.07E+07 1.27E+07 - - - 4.3447 0.9999 221125_WJC_METTL3_EV_vs_WT_F08.16823.16823.4 1.99E-05 17/72 R.C[160.03]ILPFDKETGFHR.G "sp|Q9GZT3|SLIRP_HUMAN,tr|H0YJW7|H0YJW7_HUMAN,tr|A0A087WUN7|A0A087WUN7_HUMAN,tr|G3V2S9|G3V2S9_HUMAN,tr|H0YJ40|H0YJ40_HUMAN,tr|G3V4X6|G3V4X6_HUMAN" 6 1618.7926 1.13 119679 16823 4 1618.794651 405.7054 "SRA stem-loop-interacting RNA-binding protein, mitochondrial OS=Homo sapiens OX=9606 GN=SLIRP PE=1 SV=1" 6.74 2892 - 274420 - - - 1.2688 - 2.92 0.501 - 345.7 1 2 1 0.0021 13 0 0 0 5.88E+06 5.20E+06 - - - 3.9834 0.9998 221125_WJC_METTL3_EV_vs_WT_F08.16824.16824.3 8.16E-05 Dec-72 R.SAFEEEGKETADITHALSK.L sp|Q15042|RB3GP_HUMAN 1 2061.9855 0.87 119680 16824 3 2061.991608 688.3358 Rab3 GTPase-activating protein catalytic subunit OS=Homo sapiens OX=9606 GN=RAB3GAP1 PE=1 SV=3 4.57 2892.1 - 254345 - - - 2.9724 - 3.174 0.558 - 201.9 1 2 1 0.0061 19 0 0 0 7.20E+06 8.30E+06 - - - 7.597 0.9999 221125_WJC_METTL3_EV_vs_WT_F08.16830.16830.4 0.00142 18/114 R.AISHEHSPSDLEAHFVPLVK.R "sp|P30153|2AAA_HUMAN,tr|C9J9C1|C9J9C1_HUMAN" 2 2212.1277 0.93 119684 16830 4 2212.134279 554.0392 Serine\threonine-protein phosphatase 2A 65 kDa regulatory subunit A alpha isoform OS=Homo sapiens OX=9606 GN=PPP2R1A PE=1 SV=4 5.75 2892.8 - 552261 - - - 2.989 - 2.952 0.573 - 141.4 1 2 0 0.0066 20 0 0 0 9.41E+07 1.01E+08 - - - 4.5735 0.9999 221125_WJC_METTL3_EV_vs_WT_F08.16831.16831.4 1.89E-06 17/108 R.FQSSHHPTDITSLDQYVER[166.11].M "sp|P14625|ENPL_HUMAN,tr|A0A7P0T917|A0A7P0T917_HUMAN,tr|A0A7P0T823|A0A7P0T823_HUMAN,tr|A0A7P0TAE1|A0A7P0TAE1_HUMAN,tr|H0YIV0|H0YIV0_HUMAN,tr|A0A7P0TAY2|A0A7P0TAY2_HUMAN,tr|A0A087WT78|A0A087WT78_HUMAN,tr|A0A7P0TAT8|A0A7P0TAT8_HUMAN" 8 2269.0639 0.92 119685 16831 4 2269.06706 568.2733 Endoplasmin OS=Homo sapiens OX=9606 GN=HSP90B1 PE=1 SV=1 5.21 2893 - 522937 - - - 1.3948 - 3.183 0.462 - 267.3 1 2 0 0.0032 19 0 0 0 8.12E+07 8.85E+07 - - - 3.638 0.9965 221125_WJC_METTL3_EV_vs_WT_F08.16832.16832.4 0.0885 Aug-78 K.HWPFQVINDGDK[136.11]PK[136.11].V "sp|P0DMV8|HS71A_HUMAN,sp|P0DMV9|HS71B_HUMAN,tr|A0A0G2JIW1|A0A0G2JIW1_HUMAN" 3 1695.8704 0.13 119686 16832 4 1695.870475 424.9749 Heat shock 70 kDa protein 1A OS=Homo sapiens OX=9606 GN=HSPA1A PE=1 SV=1 6.75 2893.1 - 128520 - - - 0.0501 - 1.577 0.248 - 38.3 1 2 0 0.0001 14 0 0 0 3.19E+07 2.39E+08 - - - 1.5504 0.9972 221125_WJC_METTL3_EV_vs_WT_F08.16833.16833.4 0.000611 Nov-96 K.DK[136.11]PNR[166.11]GEAQLVIPFSGK[136.11].G "sp|Q9H040|SPRTN_HUMAN,tr|B1AKT1|B1AKT1_HUMAN" 2 1881.0319 1.88 119687 16833 4 1881.035839 471.2652 DNA-dependent metalloprotease SPRTN OS=Homo sapiens OX=9606 GN=SPRTN PE=1 SV=2 8.59 2893.2 - 126957 - - - 2.1121 - 1.91 0.344 - 102.9 1 2 1 0.004 17 0 0 0 4.64E+06 2.46E+06 - - - 2.4437 0.9858 221125_WJC_METTL3_EV_vs_WT_F08.16836.16836.4 0.00425 11/120 K.KVDKIEELDQENEAALENGIK.N "sp|P43243|MATR3_HUMAN,tr|B3KM87|B3KM87_HUMAN,tr|A8MXP9|A8MXP9_HUMAN,tr|A0A0R4J2E8|A0A0R4J2E8_HUMAN,tr|D6REM6|D6REM6_HUMAN" 5 2384.2071 1.45 119688 16836 4 2384.212493 597.0591 Matrin-3 OS=Homo sapiens OX=9606 GN=MATR3 PE=1 SV=2 4.25 2893.6 - 716963 - - - 2.2624 - 2.442 0.26 - 65.7 1 2 1 0.0054 21 0 0 0 1.82E+08 1.26E+08 - - - 1.7827 1 221125_WJC_METTL3_EV_vs_WT_F08.16837.16837.4 7.04E-07 15/102 K.GQWFHISDTHVQAVPTTK.V sp|Q9Y5T5|UBP16_HUMAN 1 2051.0225 1.09 119689 16837 4 2051.025184 513.7629 Ubiquitin carboxyl-terminal hydrolase 16 OS=Homo sapiens OX=9606 GN=USP16 PE=1 SV=1 6.92 2893.8 - 658249 - - - 1.3213 - 2.99 0.499 - 133.9 1 2 0 0.0027 18 0 0 0 6.66E+06 6.09E+06 - - - 3.9437 1 221125_WJC_METTL3_EV_vs_WT_F08.16838.16838.4 1.71E-07 17/108 R.FQSSHHPTDITSLDQYVER.M "sp|P14625|ENPL_HUMAN,tr|A0A7P0T917|A0A7P0T917_HUMAN,tr|A0A7P0T823|A0A7P0T823_HUMAN,tr|A0A7P0TAE1|A0A7P0TAE1_HUMAN,tr|H0YIV0|H0YIV0_HUMAN,tr|A0A7P0TAY2|A0A7P0TAY2_HUMAN,tr|A0A087WT78|A0A087WT78_HUMAN,tr|A0A7P0TAT8|A0A7P0TAT8_HUMAN" 8 2259.0556 0.92 119690 16838 4 2259.059236 565.7712 Endoplasmin OS=Homo sapiens OX=9606 GN=HSP90B1 PE=1 SV=1 5.21 2893.8 - 993936 - - - 1.5985 - 3.128 0.499 - 230.1 1 2 0 0.0036 19 0 0 0 8.12E+07 8.84E+07 - - - 3.9541 1 221125_WJC_METTL3_EV_vs_WT_F08.16839.16839.3 1.53E-15 23/72 R.SAFEEEGK[136.11]ETADITHALSK[136.11].L sp|Q15042|RB3GP_HUMAN 1 2078.0139 0.87 119691 16839 3 2078.017888 693.6786 Rab3 GTPase-activating protein catalytic subunit OS=Homo sapiens OX=9606 GN=RAB3GAP1 PE=1 SV=3 4.57 2894 - 602051 - - - 1.9292 - 4.53 0.66 - 995.1 1 2 1 0.004 19 0 0 0 7.20E+06 8.25E+06 - - - 9.6088 0.9999 221125_WJC_METTL3_EV_vs_WT_F08.16840.16840.3 6.83E-07 20/72 R.FQSSHHPTDITSLDQYVER[166.11].M "sp|P14625|ENPL_HUMAN,tr|A0A7P0T917|A0A7P0T917_HUMAN,tr|A0A7P0T823|A0A7P0T823_HUMAN,tr|A0A7P0TAE1|A0A7P0TAE1_HUMAN,tr|H0YIV0|H0YIV0_HUMAN,tr|A0A7P0TAY2|A0A7P0TAY2_HUMAN,tr|A0A087WT78|A0A087WT78_HUMAN,tr|A0A7P0TAT8|A0A7P0TAT8_HUMAN" 8 2269.0639 0.96 119692 16840 3 2269.074291 757.3619 Endoplasmin OS=Homo sapiens OX=9606 GN=HSP90B1 PE=1 SV=1 5.21 2894.1 - 413240 - - - 4.5816 - 3.684 0.601 - 507.7 1 2 0 0.0104 19 0 0 0 3.39E+07 3.54E+07 - - - 8.4413 1 221125_WJC_METTL3_EV_vs_WT_F08.16843.16843.3 3.33E-08 18/56 R.STSHK[136.11]PDEIYGMIER[166.11].L sp|Q86U44|MTA70_HUMAN 1 1779.8581 0.02 119693 16843 3 1779.858457 594.2933 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 5.42 2894.5 - 763910 - - - 0.2264 - 3.15 0.483 - 398.9 1 2 0 0.0004 15 0 0 0 1.68E+06 7.02E+07 - - - 6.9189 1 221125_WJC_METTL3_EV_vs_WT_F08.16844.16844.3 1.55E-06 25/72 R.FQSSHHPTDITSLDQYVER.M "sp|P14625|ENPL_HUMAN,tr|A0A7P0T917|A0A7P0T917_HUMAN,tr|A0A7P0T823|A0A7P0T823_HUMAN,tr|A0A7P0TAE1|A0A7P0TAE1_HUMAN,tr|H0YIV0|H0YIV0_HUMAN,tr|A0A7P0TAY2|A0A7P0TAY2_HUMAN,tr|A0A087WT78|A0A087WT78_HUMAN,tr|A0A7P0TAT8|A0A7P0TAT8_HUMAN" 8 2259.0556 0.96 119694 16844 3 2259.058387 754.0258 Endoplasmin OS=Homo sapiens OX=9606 GN=HSP90B1 PE=1 SV=1 5.21 2894.6 - 641629 - - - 1.2226 - 4.065 0.623 - 990.3 1 2 0 0.0028 19 0 0 0 3.39E+07 3.54E+07 - - - 8.9305 0.9997 221125_WJC_METTL3_EV_vs_WT_F08.16846.16846.4 1.91E-06 19/120 K.K[136.11]VDK[136.11]IEELDQENEAALENGIK[136.11].N "sp|P43243|MATR3_HUMAN,tr|B3KM87|B3KM87_HUMAN,tr|A8MXP9|A8MXP9_HUMAN,tr|A0A0R4J2E8|A0A0R4J2E8_HUMAN,tr|D6REM6|D6REM6_HUMAN" 5 2408.2497 1.45 119696 16846 4 2408.25505 603.0697 Matrin-3 OS=Homo sapiens OX=9606 GN=MATR3 PE=1 SV=2 4.25 2894.8 - 1.02E+06 - - - 2.2219 - 3.2 0.473 - 236.9 1 2 1 0.0053 21 0 0 0 1.82E+08 1.26E+08 - - - 3.7261 1 221125_WJC_METTL3_EV_vs_WT_F08.16848.16848.3 2.81E-09 19/80 K.KVDKIEELDQENEAALENGIK.N "sp|P43243|MATR3_HUMAN,tr|B3KM87|B3KM87_HUMAN,tr|A8MXP9|A8MXP9_HUMAN,tr|A0A0R4J2E8|A0A0R4J2E8_HUMAN,tr|D6REM6|D6REM6_HUMAN" 5 2384.2071 1.42 119698 16848 3 2384.209518 795.743 Matrin-3 OS=Homo sapiens OX=9606 GN=MATR3 PE=1 SV=2 4.25 2895.1 - 614129 - - - 1.0146 - 4.074 0.599 - 528.6 1 2 1 0.0024 21 0 0 0 1.34E+08 9.45E+07 - - - 8.5851 1 221125_WJC_METTL3_EV_vs_WT_F08.16855.16855.3 5.18E-09 15/112 R.SGGDGGDEVEGSGVGAGEGETVQHFPLAR[166.11].P sp|Q96DT7|ZBT10_HUMAN 1 2780.2513 0.8 119703 16855 3 2780.249043 927.7577 Zinc finger and BTB domain-containing protein 10 OS=Homo sapiens OX=9606 GN=ZBTB10 PE=1 SV=2 4.08 2896 - 151208 - - - -0.8168 - 2.934 0.752 - 145.1 1 1 0 -0.0023 29 0 0 0 3.41E+06 4.27E+06 - - - 9.3998 0.9898 221125_WJC_METTL3_EV_vs_WT_F08.16858.16858.4 2.30E-05 12/120 K.DLANLEVPHELPTKQDGSGVK.G "sp|Q8WXI9|P66B_HUMAN,tr|A0A0U1RR34|A0A0U1RR34_HUMAN,tr|A0A0U1RRM1|A0A0U1RRM1_HUMAN,tr|A0A0U1RRK3|A0A0U1RRK3_HUMAN" 4 2246.1543 2.26 119704 16858 4 2246.16198 562.5458 Transcriptional repressor p66-beta OS=Homo sapiens OX=9606 GN=GATAD2B PE=1 SV=1 4.75 2896.4 - 385383 - - - 3.4299 - 2.601 0.34 - 40.1 2 2 1 0.0077 21 0 0 0 2.55E+07 1.13E+07 - - - 2.2699 1 221125_WJC_METTL3_EV_vs_WT_F08.16863.16863.3 6.81E-11 15/92 K.TGQGDYPLNNELDKEQEDVASTTR.K sp|O94874|UFL1_HUMAN 1 2679.226 3.93 119709 16863 3 2679.2277 894.0826 E3 UFM1-protein ligase 1 OS=Homo sapiens OX=9606 GN=UFL1 PE=1 SV=2 4.02 2897 - 310104 - - - 0.6356 - 3.467 0.669 - 117.2 1 2 1 0.0017 24 0 0 0 1.36E+07 3.46E+06 - - - 8.8859 1 221125_WJC_METTL3_EV_vs_WT_F08.16865.16865.3 5.13E-06 15/88 K.HGEVC[160.03]PAGWK[136.11]PGSETIIPDPAGK[136.11].L sp|Q13162|PRDX4_HUMAN 1 2418.1973 1.77 119711 16865 3 2418.19884 807.073 Peroxiredoxin-4 OS=Homo sapiens OX=9606 GN=PRDX4 PE=1 SV=1 5.45 2897.3 - 295272 - - - 0.6451 - 3.033 0.6 - 169.7 1 2 0 0.0016 23 0 0 0 8.39E+06 4.73E+06 - - - 7.8319 1 221125_WJC_METTL3_EV_vs_WT_F08.16868.16868.3 2.20E-14 22/80 K.K[136.11]VDK[136.11]IEELDQENEAALENGIK[136.11].N "sp|P43243|MATR3_HUMAN,tr|B3KM87|B3KM87_HUMAN,tr|A8MXP9|A8MXP9_HUMAN,tr|A0A0R4J2E8|A0A0R4J2E8_HUMAN,tr|D6REM6|D6REM6_HUMAN" 5 2408.2497 1.42 119712 16868 3 2408.249778 803.7572 Matrin-3 OS=Homo sapiens OX=9606 GN=MATR3 PE=1 SV=2 4.25 2897.7 - 3.13E+06 - - - 0.0328 - 4.075 0.687 - 622.7 1 2 1 0.0001 21 0 0 0 1.34E+08 9.45E+07 - - - 9.5675 0.9999 221125_WJC_METTL3_EV_vs_WT_F08.16872.16872.3 8.28E-06 15/84 R.NNSSSSFSPHFLGPGVGGAASK[136.11].G "sp|Q93075|TATD2_HUMAN,tr|H7C1D0|H7C1D0_HUMAN,tr|H7C1W4|H7C1W4_HUMAN" 3 2112.0116 1.61 119716 16872 3 2112.003269 705.0111 Putative deoxyribonuclease TATDN2 OS=Homo sapiens OX=9606 GN=TATDN2 PE=1 SV=2 8.76 2898.2 - 207964 - - - -3.9356 - 3.065 0.583 - 163.6 1 2 0 -0.0083 22 0 0 0 4.96E+06 3.09E+06 - - - 7.693 1 221125_WJC_METTL3_EV_vs_WT_F08.16877.16877.3 5.70E-12 21/76 R.AISHEHSPSDLEAHFVPLVK[136.11].R "sp|P30153|2AAA_HUMAN,tr|C9J9C1|C9J9C1_HUMAN" 2 2220.1419 0.94 119718 16877 3 2220.143702 741.0546 Serine\threonine-protein phosphatase 2A 65 kDa regulatory subunit A alpha isoform OS=Homo sapiens OX=9606 GN=PPP2R1A PE=1 SV=4 5.75 2898.9 - 519958 - - - 0.8265 - 4.091 0.55 - 453.1 1 2 0 0.0018 20 0 0 0 1.21E+07 1.28E+07 - - - 8.0892 0.9978 221125_WJC_METTL3_EV_vs_WT_F08.16879.16879.4 1.44E-05 13/120 R.DEPC[160.03]SSTSR[166.11]PALEEDVIYHVK[136.11].Y "sp|Q96T88|UHRF1_HUMAN,tr|A0A087WTW0|A0A087WTW0_HUMAN,tr|A0A087WVR3|A0A087WVR3_HUMAN" 3 2449.155 1.54 119720 16879 4 2450.160076 613.296 E3 ubiquitin-protein ligase UHRF1 OS=Homo sapiens OX=9606 GN=UHRF1 PE=1 SV=1 4.5 2899.1 - 598605 - - - 410.3664 - 2.35 0.466 - 106.2 1 2 0 1.0051 21 0 0 0 2.80E+07 1.81E+07 - - - 3.2862 0.9964 221125_WJC_METTL3_EV_vs_WT_F08.16880.16880.4 0.0163 16/120 K.ETPPTAHLILPEQHMSLAQQK.A "sp|Q8IWZ3|ANKH1_HUMAN,tr|H0Y472|H0Y472_HUMAN,tr|H0Y7Y3|H0Y7Y3_HUMAN,tr|H0Y4P6|H0Y4P6_HUMAN,tr|H0Y785|H0Y785_HUMAN" 5 2368.2209 1.35 119721 16880 4 2368.226876 593.0625 Ankyrin repeat and KH domain-containing protein 1 OS=Homo sapiens OX=9606 GN=ANKHD1 PE=1 SV=1 6.01 2899.3 - 567721 - - - 2.5167 - 2.419 0.269 - 158.1 1 2 0 0.006 21 0 0 0 1.34E+07 9.92E+06 - - - 1.8578 1 221125_WJC_METTL3_EV_vs_WT_F08.16881.16881.3 2.34E-09 12/112 R.SGGDGGDEVEGSGVGAGEGETVQHFPLAR.P sp|Q96DT7|ZBT10_HUMAN 1 2770.243 0.8 119722 16881 3 2770.241201 924.4216 Zinc finger and BTB domain-containing protein 10 OS=Homo sapiens OX=9606 GN=ZBTB10 PE=1 SV=2 4.08 2899.4 - 241496 - - - -0.6653 - 2.765 0.696 - 87.4 1 1 0 -0.0018 29 0 0 0 3.41E+06 4.27E+06 - - - 8.639 0.9998 221125_WJC_METTL3_EV_vs_WT_F08.16883.16883.3 1.72E-05 Dec-84 R.DVDELPSLQPSVGSPSRPSSSR.L sp|O43815|STRN_HUMAN 1 2296.1295 1.4 119724 16883 3 2296.133821 766.3838 Striatin OS=Homo sapiens OX=9606 GN=STRN PE=1 SV=4 4.56 2899.6 - 206758 - - - 1.874 - 2.163 0.428 - 73.5 1 2 0 0.0043 22 0 0 0 1.18E+07 8.41E+06 - - - 5.1397 0.9982 221125_WJC_METTL3_EV_vs_WT_F08.16887.16887.3 0.000464 19/76 F.GQSPFSQPPAPPHQNTFPPR.S sp|Q96I24|FUBP3_HUMAN 1 2186.0657 1.45 119726 16887 3 2186.067754 729.6959 Far upstream element-binding protein 3 OS=Homo sapiens OX=9606 GN=FUBP3 PE=1 SV=2 9.76 2900.1 - 681493 - - - 0.9231 - 4.04 0.488 - 300.7 1 1 0 0.002 20 0 0 0 1.52E+07 1.05E+07 - - - 7.3675 0.9992 221125_WJC_METTL3_EV_vs_WT_F08.16888.16888.3 0.00138 Dec-80 K.DLANLEVPHELPTKQDGSGVK.G "sp|Q8WXI9|P66B_HUMAN,tr|A0A0U1RR34|A0A0U1RR34_HUMAN,tr|A0A0U1RRM1|A0A0U1RRM1_HUMAN,tr|A0A0U1RRK3|A0A0U1RRK3_HUMAN" 4 2246.1543 2.7 119727 16888 3 2246.159637 749.7254 Transcriptional repressor p66-beta OS=Homo sapiens OX=9606 GN=GATAD2B PE=1 SV=1 4.75 2900.2 - 387833 - - - 2.3867 - 2.727 0.418 - 90.6 1 2 1 0.0054 21 0 0 0 6.69E+06 2.48E+06 - - - 5.6039 0.9997 221125_WJC_METTL3_EV_vs_WT_F08.16891.16891.3 7.31E-05 13/84 R.DVDELPSLQPSVGSPSR[166.11]PSSSR[166.11].L sp|O43815|STRN_HUMAN 1 2316.1461 1.47 119730 16891 3 2316.141933 773.056 Striatin OS=Homo sapiens OX=9606 GN=STRN PE=1 SV=4 4.56 2900.6 - 283731 - - - -1.781 - 2.458 0.344 - 105 1 2 0 -0.0041 22 0 0 0 1.18E+07 8.03E+06 - - - 4.5063 1 221125_WJC_METTL3_EV_vs_WT_F08.16894.16894.3 3.10E-12 27/84 R.QNSQLPAQVQNGPSQEELEIQR.R "sp|Q8N8S7|ENAH_HUMAN,tr|A0A0U1RQP7|A0A0U1RQP7_HUMAN,tr|A0A075B6E5|A0A075B6E5_HUMAN,tr|A0A0U1RRM6|A0A0U1RRM6_HUMAN" 4 2492.2255 1.52 119731 16894 3 2492.226119 831.7491 Protein enabled homolog OS=Homo sapiens OX=9606 GN=ENAH PE=1 SV=2 4.25 2901 - 2.73E+06 - - - 0.2311 - 4.532 0.623 - 1125.1 1 2 0 0.0006 22 0 0 0 3.34E+07 2.19E+07 - - - 9.0684 1 221125_WJC_METTL3_EV_vs_WT_F08.16895.16895.3 1.53E-12 20/76 R.AISHEHSPSDLEAHFVPLVK.R "sp|P30153|2AAA_HUMAN,tr|C9J9C1|C9J9C1_HUMAN" 2 2212.1277 0.92 119732 16895 3 2212.129617 738.3832 Serine\threonine-protein phosphatase 2A 65 kDa regulatory subunit A alpha isoform OS=Homo sapiens OX=9606 GN=PPP2R1A PE=1 SV=4 5.75 2901.1 - 590016 - - - 0.8815 - 4.317 0.603 - 450 1 2 0 0.0019 20 0 0 0 1.18E+07 1.29E+07 - - - 8.8105 1 221125_WJC_METTL3_EV_vs_WT_F08.16904.16904.4 3.06E-06 13/78 K.HWPFQVINDGDKPK.V "sp|P0DMV8|HS71A_HUMAN,sp|P0DMV9|HS71B_HUMAN,tr|A0A0G2JIW1|A0A0G2JIW1_HUMAN" 3 1679.842 0.13 119739 16904 4 1679.842329 420.9678 Heat shock 70 kDa protein 1A OS=Homo sapiens OX=9606 GN=HSPA1A PE=1 SV=1 6.75 2902.3 - 195652 - - - 0.2018 - 2.388 0.578 - 116.6 1 2 0 0.0003 14 0 0 0 3.19E+07 2.38E+08 - - - 4.5736 0.9998 221125_WJC_METTL3_EV_vs_WT_F08.16912.16912.3 0.000112 Oct-92 K.SK[136.11]LESGLTNGDEPMDQDLSDVPTK[136.11].C sp|Q9P2I0|CPSF2_HUMAN 1 2591.2243 0.75 119745 16912 3 2591.224257 864.7487 Cleavage and polyadenylation specificity factor subunit 2 OS=Homo sapiens OX=9606 GN=CPSF2 PE=1 SV=2 3.96 2903.3 - 140465 - - - -0.0332 - 2.233 0.503 - 70.3 1 2 1 -0.0001 24 0 0 0 2.35E+06 3.12E+06 - - - 6.0138 1 221125_WJC_METTL3_EV_vs_WT_F08.16914.16914.4 5.75E-10 30/138 K.IHVSDQELQSANASVDDSR[166.11]LEELK[136.11].A "sp|P22314|UBA1_HUMAN,tr|Q5JRR6|Q5JRR6_HUMAN" 2 2700.3321 0.55 119747 16914 4 2700.334089 676.0903 Ubiquitin-like modifier-activating enzyme 1 OS=Homo sapiens OX=9606 GN=UBA1 PE=1 SV=3 4.29 2903.6 - 1.05E+06 - - - 0.7229 - 5.218 0.64 - 630.5 1 2 1 0.002 24 0 0 0 1.66E+07 3.03E+07 - - - 5.3263 1 221125_WJC_METTL3_EV_vs_WT_F08.16921.16921.3 1.02E-05 23/52 K.HWPFQVINDGDK[136.11]PK[136.11].V "sp|P0DMV8|HS71A_HUMAN,sp|P0DMV9|HS71B_HUMAN,tr|A0A0G2JIW1|A0A0G2JIW1_HUMAN" 3 1695.8704 0.13 119752 16921 3 1695.872016 566.2974 Heat shock 70 kDa protein 1A OS=Homo sapiens OX=9606 GN=HSPA1A PE=1 SV=1 6.75 2904.5 - 4.10E+06 - - - 0.9588 - 3.513 0.582 - 1036.7 1 2 0 0.0016 14 0 0 0 1.15E+08 8.67E+08 - - - 8.3674 1 221125_WJC_METTL3_EV_vs_WT_F08.16929.16929.4 4.13E-09 25/138 K.IHVSDQELQSANASVDDSRLEELK.A "sp|P22314|UBA1_HUMAN,tr|Q5JRR6|Q5JRR6_HUMAN" 2 2682.3097 0.55 119758 16929 4 2682.31562 671.5847 Ubiquitin-like modifier-activating enzyme 1 OS=Homo sapiens OX=9606 GN=UBA1 PE=1 SV=3 4.29 2905.6 - 1.47E+06 - - - 2.2194 - 4.849 0.641 - 427.3 1 2 1 0.006 24 0 0 0 1.66E+07 3.03E+07 - - - 5.3103 1 221125_WJC_METTL3_EV_vs_WT_F08.16930.16930.3 1.31E-08 29/92 K.IHVSDQELQSANASVDDSR[166.11]LEELK[136.11].A "sp|P22314|UBA1_HUMAN,tr|Q5JRR6|Q5JRR6_HUMAN" 2 2700.3321 0.58 119759 16930 3 2701.337131 901.118 Ubiquitin-like modifier-activating enzyme 1 OS=Homo sapiens OX=9606 GN=UBA1 PE=1 SV=3 4.29 2905.7 - 436337 - - - 372.1742 - 5.782 0.668 - 668.7 1 2 1 1.005 24 0 0 0 3.47E+06 5.96E+06 - - - 9.7847 0.9996 221125_WJC_METTL3_EV_vs_WT_F08.16933.16933.4 0.0107 12/120 K.ETTYYDVLGVK[136.11]PNATQEELK[136.11]K[136.11].A sp|P31689|DNJA1_HUMAN 1 2449.2803 0.65 119762 16933 4 2449.284587 613.3273 DnaJ homolog subfamily A member 1 OS=Homo sapiens OX=9606 GN=DNAJA1 PE=1 SV=2 4.87 2906.1 - 316644 - - - 1.7622 - 2.265 0.352 - 88.9 1 2 0 0.0043 21 0 0 0 6.34E+07 9.80E+07 - - - 2.5589 0.9998 221125_WJC_METTL3_EV_vs_WT_F08.16934.16934.3 0.000118 Nov-52 K.SFFDNISC[160.03]DDNR[166.11]ER[166.11].R "sp|Q8ND56|LS14A_HUMAN,tr|A0A096LP11|A0A096LP11_HUMAN,tr|A0A140TA76|A0A140TA76_HUMAN,tr|A0A0G2JQ95|A0A0G2JQ95_HUMAN" 4 1793.7542 1 119763 16934 3 1793.753534 598.9253 Protein LSM14 homolog A OS=Homo sapiens OX=9606 GN=LSM14A PE=1 SV=3 4.23 2906.2 - 250709 - - - -0.3718 - 2.068 0.527 - 110.1 1 2 1 -0.0007 14 0 0 0 3.72E+07 3.71E+07 - - - 6.3463 1 221125_WJC_METTL3_EV_vs_WT_F08.16939.16939.4 2.61E-11 24/114 R.AISHEHSPSDLEAHFVPLVK[136.11].R "sp|P30153|2AAA_HUMAN,tr|C9J9C1|C9J9C1_HUMAN" 2 2220.1419 0.93 119767 16939 4 2220.146172 556.0427 Serine\threonine-protein phosphatase 2A 65 kDa regulatory subunit A alpha isoform OS=Homo sapiens OX=9606 GN=PPP2R1A PE=1 SV=4 5.75 2906.8 - 3.77E+06 - - - 1.9391 - 4.513 0.691 - 278.7 1 2 0 0.0043 20 0 0 0 9.41E+07 1.01E+08 - - - 5.7431 0.9483 221125_WJC_METTL3_EV_vs_WT_F08.16946.16946.4 0.986 Sep-96 K.QVK[136.11]PYVEEGLHPQIIIR[166.11].A "sp|Q99832|TCPH_HUMAN,tr|F8WAM2|F8WAM2_HUMAN" 2 2036.1538 0.12 119773 16946 4 2036.154562 510.0457 T-complex protein 1 subunit eta OS=Homo sapiens OX=9606 GN=CCT7 PE=1 SV=2 6.76 2907.7 - 109282 - - - 0.3909 - 1.489 0.143 - 48.2 1 2 0 0.0008 17 0 0 0 1.50E+06 1.30E+07 - - - 0.6087 0.9998 221125_WJC_METTL3_EV_vs_WT_F08.16950.16950.3 1.30E-06 14/52 K.SFFDNISC[160.03]DDNRER.R "sp|Q8ND56|LS14A_HUMAN,tr|A0A096LP11|A0A096LP11_HUMAN,tr|A0A140TA76|A0A140TA76_HUMAN,tr|A0A0G2JQ95|A0A0G2JQ95_HUMAN" 4 1773.7377 1 119775 16950 3 1773.741551 592.2532 Protein LSM14 homolog A OS=Homo sapiens OX=9606 GN=LSM14A PE=1 SV=3 4.23 2908.2 - 820131 - - - 2.1931 - 2.211 0.609 - 206.5 1 2 1 0.0039 14 0 0 0 3.72E+07 3.71E+07 - - - 7.4373 1 221125_WJC_METTL3_EV_vs_WT_F08.16951.16951.3 1.19E-06 19/76 R.QQVAFYGQTLGQAQAHSQEQ.- sp|Q96I24|FUBP3_HUMAN 1 2218.0403 - 119776 16951 3 2218.043536 740.354 Far upstream element-binding protein 3 OS=Homo sapiens OX=9606 GN=FUBP3 PE=1 SV=2 5.24 2908.4 - 783512 - - - 1.4549 - 3.161 0.492 - 370.9 1 2 0 0.0032 20 0 0 0 - - - - - 6.8165 0.999 221125_WJC_METTL3_EV_vs_WT_F08.16952.16952.4 0.000566 14/120 K.ETTYYDVLGVKPNATQEELKK.A sp|P31689|DNJA1_HUMAN 1 2425.2377 0.69 119777 16952 4 2425.248257 607.3167 DnaJ homolog subfamily A member 1 OS=Homo sapiens OX=9606 GN=DNAJA1 PE=1 SV=2 4.87 2908.5 - 497130 - - - 4.3649 - 2.58 0.412 - 123.3 1 2 0 0.0106 21 0 0 0 6.80E+07 9.83E+07 - - - 3.1225 1 221125_WJC_METTL3_EV_vs_WT_F08.16953.16953.3 1.29E-12 23/92 K.IHVSDQELQSANASVDDSRLEELK.A "sp|P22314|UBA1_HUMAN,tr|Q5JRR6|Q5JRR6_HUMAN" 2 2682.3097 0.58 119778 16953 3 2682.315413 895.1105 Ubiquitin-like modifier-activating enzyme 1 OS=Homo sapiens OX=9606 GN=UBA1 PE=1 SV=3 4.29 2908.6 - 453398 - - - 2.1422 - 4.47 0.653 - 374.6 1 2 1 0.0057 24 0 0 0 3.47E+06 5.96E+06 - - - 9.2965 1 221125_WJC_METTL3_EV_vs_WT_F08.16954.16954.3 3.03E-07 21/64 K.K[136.11]K[136.11]VDDDLGTIESLEEAK[136.11].K sp|P35580|MYH10_HUMAN 1 1913.0056 0.87 119779 16954 3 1913.007084 638.6758 Myosin-10 OS=Homo sapiens OX=9606 GN=MYH10 PE=1 SV=3 4.3 2908.8 - 434218 - - - 0.8003 - 3.716 0.568 - 690.2 1 2 1 0.0015 17 0 0 0 4.99E+07 5.76E+07 - - - 8.1884 0.9995 221125_WJC_METTL3_EV_vs_WT_F08.16956.16956.4 7.96E-07 17/96 K.K[136.11]K[136.11]VDDDLGTIESLEEAK[136.11].K sp|P35580|MYH10_HUMAN 1 1913.0056 0.94 119781 16956 4 1913.010703 479.2587 Myosin-10 OS=Homo sapiens OX=9606 GN=MYH10 PE=1 SV=3 4.3 2909 - 225909 - - - 2.6921 - 2.816 0.473 - 323.1 1 2 1 0.0052 17 0 0 0 2.17E+07 2.31E+07 - - - 3.701 0.9997 221125_WJC_METTL3_EV_vs_WT_F08.16957.16957.4 3.07E-06 15/96 K.KKVDDDLGTIESLEEAK.K sp|P35580|MYH10_HUMAN 1 1888.963 0.94 119782 16957 4 1888.966889 473.248 Myosin-10 OS=Homo sapiens OX=9606 GN=MYH10 PE=1 SV=3 4.3 2909.1 - 218433 - - - 2.0837 - 2.815 0.477 - 242.9 1 2 1 0.0039 17 0 0 0 2.17E+07 2.31E+07 - - - 3.7361 0.9999 221125_WJC_METTL3_EV_vs_WT_F08.16965.16965.4 2.97E-06 14/96 K.ANHPHNVQSQVVEAFIR[166.11].W sp|P78560|CRADD_HUMAN 1 1955.0001 2.24 119788 16965 4 1955.005504 489.7573 Death domain-containing protein CRADD OS=Homo sapiens OX=9606 GN=CRADD PE=1 SV=1 6.96 2910.2 - 242343 - - - 2.7581 - 3.306 0.552 - 174.3 1 2 0 0.0054 17 0 0 0 7.02E+06 3.14E+06 - - - 4.4443 1 221125_WJC_METTL3_EV_vs_WT_F08.16971.16971.4 2.88E-07 23/138 R.TYHPPAQLTHTQFPAASSVGLPSR[166.11].T sp|Q96T58|MINT_HUMAN 1 2572.3062 1.38 119792 16971 4 2572.309747 644.0838 Msx2-interacting protein OS=Homo sapiens OX=9606 GN=SPEN PE=1 SV=1 8.47 2911 - 1.12E+06 - - - 1.3824 - 3.588 0.49 - 230.6 1 2 0 0.0036 24 0 0 0 6.32E+07 4.57E+07 - - - 3.9 1 221125_WJC_METTL3_EV_vs_WT_F08.16975.16975.3 0.000817 21/80 K.ETTYYDVLGVK[136.11]PNATQEELK[136.11]K[136.11].A sp|P31689|DNJA1_HUMAN 1 2449.2803 0.64 119796 16975 3 2449.285167 817.434 DnaJ homolog subfamily A member 1 OS=Homo sapiens OX=9606 GN=DNAJA1 PE=1 SV=2 4.87 2911.4 - 860092 - - - 1.999 - 3.916 0.568 - 427.6 1 2 0 0.0049 21 0 0 0 1.04E+07 1.63E+07 - - - 8.144 1 221125_WJC_METTL3_EV_vs_WT_F08.16977.16977.4 3.26E-12 20/96 K.ANHPHNVQSQVVEAFIR.W sp|P78560|CRADD_HUMAN 1 1944.9918 2.06 119798 16977 4 1944.993618 487.2552 Death domain-containing protein CRADD OS=Homo sapiens OX=9606 GN=CRADD PE=1 SV=1 6.96 2911.6 - 609661 - - - 0.9131 - 4.26 0.635 - 411.2 1 2 0 0.0018 17 0 0 0 6.46E+06 3.14E+06 - - - 5.2557 0.9259 221125_WJC_METTL3_EV_vs_WT_F08.16980.16980.2 0.0416 14-Jun V.INDGDK[136.11]PK[136.11].V "sp|P0DMV8|HS71A_HUMAN,sp|P0DMV9|HS71B_HUMAN,tr|A0A0G2JIW1|A0A0G2JIW1_HUMAN" 3 901.484 0.08 119801 16980 2 901.483427 451.7493 Heat shock 70 kDa protein 1A OS=Homo sapiens OX=9606 GN=HSPA1A PE=1 SV=1 5.96 2912 - 183633 - - - -0.6312 - 1.293 0.319 - 63.9 1 1 0 -0.0006 8 0 0 0 8.01E+05 9.84E+06 - - - 2.172 1 221125_WJC_METTL3_EV_vs_WT_F08.16985.16985.3 4.77E-10 17/80 K.ETTYYDVLGVKPNATQEELKK.A sp|P31689|DNJA1_HUMAN 1 2425.2377 0.78 119804 16985 3 2425.239247 809.4198 DnaJ homolog subfamily A member 1 OS=Homo sapiens OX=9606 GN=DNAJA1 PE=1 SV=2 4.87 2912.6 - 586813 - - - 0.6498 - 3.272 0.559 - 272.3 1 2 0 0.0016 21 0 0 0 1.28E+07 1.63E+07 - - - 7.6138 0.8115 221125_WJC_METTL3_EV_vs_WT_F08.16989.16989.4 0.0146 15/102 A.KITNEKGEC[160.03]IVSDFTIGR.K "sp|P52948|NUP98_HUMAN,tr|A0A3B3ITD8|A0A3B3ITD8_HUMAN" 2 2066.0466 2.17 119808 16989 4 2066.05032 517.5189 Nuclear pore complex protein Nup98-Nup96 OS=Homo sapiens OX=9606 GN=NUP98 PE=1 SV=4 6.17 2913.1 - 387657 - - - 1.7812 - 2.533 0.342 - 157.2 1 1 1 0.0037 18 0 0 0 4.23E+06 1.95E+06 - - - 2.5201 1 221125_WJC_METTL3_EV_vs_WT_F08.16990.16990.2 1.06E-09 14/38 R.QQVAFYGQTLGQAQAHSQEQ.- sp|Q96I24|FUBP3_HUMAN 1 2218.0403 - 119809 16990 2 2218.040845 1110.0274 Far upstream element-binding protein 3 OS=Homo sapiens OX=9606 GN=FUBP3 PE=1 SV=2 5.24 2913.3 - 362263 - - - 0.2417 - 2.73 0.638 - 351.8 1 2 0 0.0005 20 0 0 0 - - - - - 6.2222 0.9997 221125_WJC_METTL3_EV_vs_WT_F08.16994.16994.2 2.47E-07 24-Sep R.TTPSYVAFTDTER.L "sp|P48741|HSP77_HUMAN,sp|P54652|HSP72_HUMAN,sp|P0DMV8|HS71A_HUMAN,sp|P34931|HS71L_HUMAN,sp|P11142|HSP7C_HUMAN,sp|P0DMV9|HS71B_HUMAN,sp|P17066|HSP76_HUMAN,tr|E9PQQ4|E9PQQ4_HUMAN,tr|E9PNE6|E9PNE6_HUMAN,tr|E9PKE3|E9PKE3_HUMAN,tr|E9PLF4|E9PLF4_HUMAN,tr|Q53FA3|Q53FA3_HUMAN,tr|E9PI65|E9PI65_HUMAN,tr|E9PK54|E9PK54_HUMAN,tr|E9PN25|E9PN25_HUMAN,tr|E9PPY6|E9PPY6_HUMAN,tr|E9PQK7|E9PQK7_HUMAN,tr|A0A0G2JIW1|A0A0G2JIW1_HUMAN" 18 1486.694 0.18 119813 16994 2 1486.697451 744.3543 Putative heat shock 70 kDa protein 7 OS=Homo sapiens OX=9606 GN=HSPA7 PE=5 SV=2 4.37 2913.8 - 235770 - - - 2.3287 - 2.099 0.583 - 262.2 1 2 0 0.0035 13 0 0 0 3.03E+06 1.71E+07 - - - 5.2489 1 221125_WJC_METTL3_EV_vs_WT_F08.16998.16998.3 5.98E-12 20/60 K.KQC[160.03]ASLQAAIADAEQR.G sp|P48668|K2C6C_HUMAN 1 1758.8683 999 119815 16998 3 1758.868236 587.2967 "Keratin, type II cytoskeletal 6C OS=Homo sapiens OX=9606 GN=KRT6C PE=1 SV=3" 6.06 2914.4 - 1.94E+06 - - - -0.0262 - 3.928 0.581 - 662.5 1 2 0 0 16 0 0 0 2.98E+07 0.00E+00 - - - 8.528 1 221125_WJC_METTL3_EV_vs_WT_F08.16999.16999.3 2.77E-08 19/52 K.HWPFQVINDGDKPK.V "sp|P0DMV8|HS71A_HUMAN,sp|P0DMV9|HS71B_HUMAN,tr|A0A0G2JIW1|A0A0G2JIW1_HUMAN" 3 1679.842 0.13 119816 16999 3 1679.841853 560.9546 Heat shock 70 kDa protein 1A OS=Homo sapiens OX=9606 GN=HSPA1A PE=1 SV=1 6.75 2914.4 - 1.97E+06 - - - -0.0816 - 3.462 0.512 - 704.6 1 2 0 -0.0001 14 0 0 0 1.15E+08 8.66E+08 - - - 7.5485 1 221125_WJC_METTL3_EV_vs_WT_F08.17004.17004.2 7.53E-10 16/28 K.QISNLQQSISDAEQR.G sp|P04264|K2C1_HUMAN 1 1715.8438 999 119821 17004 2 1715.845607 858.9292 "Keratin, type II cytoskeletal 1 OS=Homo sapiens OX=9606 GN=KRT1 PE=1 SV=6" 4.37 2915 - 411933 - - - 1.0292 - 3.153 0.585 - 985.5 1 2 0 0.0018 15 0 0 0 2.99E+07 0.00E+00 - - - 6.1845 0.7745 221125_WJC_METTL3_EV_vs_WT_F08.17010.17010.3 1.44 Aug-64 K.RDYDFSRAQSTYFNDPK[136.11].W "sp|Q92824|PCSK5_HUMAN,tr|A0A669KA35|A0A669KA35_HUMAN,tr|B1AMG5|B1AMG5_HUMAN" 3 2116.9694 - 119825 17010 3 2116.970845 706.6637 Proprotein convertase subtilisin\kexin type 5 OS=Homo sapiens OX=9606 GN=PCSK5 PE=1 SV=4 6.04 2915.8 - 6.48E+06 - - - 0.6911 - 1.33 0.134 - 47.3 1 2 1 0.0015 17 0 0 0 - - - - - 0.754 0.9999 221125_WJC_METTL3_EV_vs_WT_F08.17011.17011.3 1.63E-07 17/64 K.KKVDDDLGTIESLEEAK.K sp|P35580|MYH10_HUMAN 1 1888.963 0.87 119826 17011 3 1888.96252 630.6616 Myosin-10 OS=Homo sapiens OX=9606 GN=MYH10 PE=1 SV=3 4.3 2915.9 - 3.44E+06 - - - -0.2292 - 3.254 0.527 - 429.7 1 2 1 -0.0004 17 0 0 0 4.99E+07 5.75E+07 - - - 7.3962 1 221125_WJC_METTL3_EV_vs_WT_F08.17012.17012.3 2.60E-07 16/56 K.QISNLQQSISDAEQR.G sp|P04264|K2C1_HUMAN 1 1715.8438 61.24 119827 17012 3 1715.845624 572.9552 "Keratin, type II cytoskeletal 1 OS=Homo sapiens OX=9606 GN=KRT1 PE=1 SV=6" 4.37 2916 - 1.84E+06 - - - 1.0391 - 3.046 0.532 - 331.5 1 2 0 0.0018 15 0 0 0 5.20E+07 8.49E+05 - - - 7.3772 0.9999 221125_WJC_METTL3_EV_vs_WT_F08.17020.17020.3 6.88E-07 16/56 K.NK[136.11]DQGTYEDYVEGLR[166.11].V "sp|P60660|MYL6_HUMAN,tr|F8W1R7|F8W1R7_HUMAN,tr|G3V1V0|G3V1V0_HUMAN,tr|B7Z6Z4|B7Z6Z4_HUMAN,tr|F8VZU9|F8VZU9_HUMAN,tr|G8JLA2|G8JLA2_HUMAN,tr|H0YI43|H0YI43_HUMAN,tr|F8W180|F8W180_HUMAN,tr|G3V1Y7|G3V1Y7_HUMAN,tr|J3KND3|J3KND3_HUMAN,tr|F8VPF3|F8VPF3_HUMAN" 11 1803.8394 1.27 119833 17020 3 1803.839484 602.2871 Myosin light polypeptide 6 OS=Homo sapiens OX=9606 GN=MYL6 PE=1 SV=2 4.32 2917 - 894733 - - - 0.0316 - 2.842 0.564 - 260.8 1 2 1 0.0001 15 0 0 0 1.70E+07 1.34E+07 - - - 7.5535 0.9999 221125_WJC_METTL3_EV_vs_WT_F08.17035.17035.3 1.21E-06 16/52 K.HWPFQVINDGDKPK[136.11].V "sp|P0DMV8|HS71A_HUMAN,sp|P0DMV9|HS71B_HUMAN,tr|A0A0G2JIW1|A0A0G2JIW1_HUMAN" 3 1687.8562 - 119846 17035 3 1687.857009 563.626 Heat shock 70 kDa protein 1A OS=Homo sapiens OX=9606 GN=HSPA1A PE=1 SV=1 6.75 2918.9 - 405966 - - - 0.4852 - 2.848 0.401 - 287.1 2 2 0 0.0008 14 0 0 0 - - - - - 5.6526 0.9999 221125_WJC_METTL3_EV_vs_WT_F08.17038.17038.4 0.00122 13/84 R.STSHK[136.11]PDEIYGMIER[166.11].L sp|Q86U44|MTA70_HUMAN 1 1779.8581 0.01 119848 17038 4 1779.856467 445.9718 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 5.42 2919.3 - 517895 - - - -0.8916 - 2.109 0.422 - 129.6 1 2 0 -0.0016 15 0 0 0 1.69E+05 1.99E+07 - - - 3.1657 0.9614 221125_WJC_METTL3_EV_vs_WT_F08.17047.17047.2 0.00207 16-Aug Q.VINDGDK[136.11]PK[136.11].V "sp|P0DMV8|HS71A_HUMAN,sp|P0DMV9|HS71B_HUMAN,tr|A0A0G2JIW1|A0A0G2JIW1_HUMAN" 3 1000.5524 0.06 119854 17047 2 1000.553567 501.2835 Heat shock 70 kDa protein 1A OS=Homo sapiens OX=9606 GN=HSPA1A PE=1 SV=1 5.93 2920.4 - 453952 - - - 1.1564 - 1.544 0.378 - 150.9 1 1 0 0.0012 9 0 0 0 9.87E+05 1.53E+07 - - - 3.0892 0.9997 221125_WJC_METTL3_EV_vs_WT_F08.17054.17054.4 1.09E-06 17/96 R.EDLR[166.11]LPEGDLGK[136.11]EIEQK[136.11].Y "sp|P63241|IF5A1_HUMAN,sp|Q6IS14|IF5AL_HUMAN,tr|I3L397|I3L397_HUMAN,tr|I3L504|I3L504_HUMAN" 4 1994.0531 1.05 119859 17054 4 1994.051574 499.5205 Eukaryotic translation initiation factor 5A-1 OS=Homo sapiens OX=9606 GN=EIF5A PE=1 SV=2 4.36 2921.3 - 334787 - - - -0.7427 - 2.701 0.437 - 138.4 1 2 2 -0.0015 17 0 0 0 9.63E+07 9.19E+07 - - - 3.3742 0.9881 221125_WJC_METTL3_EV_vs_WT_F08.17061.17061.4 0.0208 15/96 R.EDLRLPEGDLGKEIEQK.Y "sp|P63241|IF5A1_HUMAN,sp|Q6IS14|IF5AL_HUMAN,tr|I3L397|I3L397_HUMAN,tr|I3L504|I3L504_HUMAN" 4 1968.0164 1.05 119864 17061 4 1968.018338 493.0114 Eukaryotic translation initiation factor 5A-1 OS=Homo sapiens OX=9606 GN=EIF5A PE=1 SV=2 4.36 2922.2 - 466494 - - - 0.9924 - 1.95 0.247 - 98.6 1 2 2 0.002 17 0 0 0 9.63E+07 9.19E+07 - - - 1.6072 0.9986 221125_WJC_METTL3_EV_vs_WT_F08.17062.17062.4 0.000216 16/120 K.HGYEKPTPIQTQAIPAIMSGR.D "sp|Q7L014|DDX46_HUMAN,tr|D6RJA6|D6RJA6_HUMAN,tr|A0A0C4DG89|A0A0C4DG89_HUMAN" 3 2294.1841 1.26 119865 17062 4 2294.173954 574.5533 Probable ATP-dependent RNA helicase DDX46 OS=Homo sapiens OX=9606 GN=DDX46 PE=1 SV=2 8.6 2922.3 - 273298 - - - -4.4382 - 2.508 0.391 - 135.4 1 2 0 -0.0102 21 0 0 0 6.33E+06 5.01E+06 - - - 2.9305 0.9999 221125_WJC_METTL3_EV_vs_WT_F08.17067.17067.3 1.03E-07 18/64 R.EDLRLPEGDLGKEIEQK.Y "sp|P63241|IF5A1_HUMAN,sp|Q6IS14|IF5AL_HUMAN,tr|I3L397|I3L397_HUMAN,tr|I3L504|I3L504_HUMAN" 4 1968.0164 1.08 119868 17067 3 1968.018295 657.0127 Eukaryotic translation initiation factor 5A-1 OS=Homo sapiens OX=9606 GN=EIF5A PE=1 SV=2 4.36 2922.9 - 531402 - - - 0.9705 - 3.372 0.46 - 448.2 1 2 2 0.0019 17 0 0 0 5.87E+07 5.43E+07 - - - 6.7388 1 221125_WJC_METTL3_EV_vs_WT_F08.17068.17068.4 6.57E-10 23/162 R.GPNGASAGVAAQHSQC[160.03]FAAWYGHC[160.03]PGLK.V "sp|P11177|ODPB_HUMAN,tr|F8WF02|F8WF02_HUMAN,tr|C9J634|C9J634_HUMAN" 3 2898.3079 1.32 119869 17068 4 2898.304734 725.5842 "Pyruvate dehydrogenase E1 component subunit beta, mitochondrial OS=Homo sapiens OX=9606 GN=PDHB PE=1 SV=3" 8.06 2923.1 - 473476 - - - -1.0755 - 3.753 0.648 - 223.1 1 2 0 -0.0031 28 0 0 0 6.63E+06 5.04E+06 - - - 5.276 1 221125_WJC_METTL3_EV_vs_WT_F08.17069.17069.3 1.45E-10 21/64 R.EDLR[166.11]LPEGDLGK[136.11]EIEQK[136.11].Y "sp|P63241|IF5A1_HUMAN,sp|Q6IS14|IF5AL_HUMAN,tr|I3L397|I3L397_HUMAN,tr|I3L504|I3L504_HUMAN" 4 1994.0531 1.08 119870 17069 3 1994.054667 665.6916 Eukaryotic translation initiation factor 5A-1 OS=Homo sapiens OX=9606 GN=EIF5A PE=1 SV=2 4.36 2923.2 - 469551 - - - 0.8084 - 4.292 0.552 - 699.5 1 2 2 0.0016 17 0 0 0 5.87E+07 5.43E+07 - - - 8.374 1 221125_WJC_METTL3_EV_vs_WT_F08.17072.17072.4 1.60E-08 18/78 K.HWPFQVINDGDK[136.11]PK[136.11].V "sp|P0DMV8|HS71A_HUMAN,sp|P0DMV9|HS71B_HUMAN,tr|A0A0G2JIW1|A0A0G2JIW1_HUMAN" 3 1695.8704 0.13 119872 17072 4 1695.870736 424.9749 Heat shock 70 kDa protein 1A OS=Homo sapiens OX=9606 GN=HSPA1A PE=1 SV=1 6.75 2923.6 - 4.77E+06 - - - 0.204 - 3.016 0.607 - 259.5 1 2 0 0.0003 14 0 0 0 3.19E+07 2.39E+08 - - - 4.911 0.9999 221125_WJC_METTL3_EV_vs_WT_F08.17074.17074.4 1.81E-07 12/120 K.LLTQHENIKNEIDNYEEDYQK.M "sp|Q01082|SPTB2_HUMAN,tr|A0A087WUZ3|A0A087WUZ3_HUMAN" 2 2635.2402 1.49 119873 17074 4 2635.243176 659.8173 "Spectrin beta chain, non-erythrocytic 1 OS=Homo sapiens OX=9606 GN=SPTBN1 PE=1 SV=2" 4.35 2923.8 - 602096 - - - 1.1327 - 2.696 0.51 - 107.8 1 2 1 0.003 21 0 0 0 4.35E+07 2.92E+07 - - - 3.9921 1 221125_WJC_METTL3_EV_vs_WT_F08.17083.17083.3 5.74E-12 22/96 K.SSSSSSQPEHSAMLVSTAASPSLIK[136.11].E sp|P42166|LAP2A_HUMAN 1 2496.2257 0.77 119878 17083 3 2496.226859 833.0825 "Lamina-associated polypeptide 2, isoform alpha OS=Homo sapiens OX=9606 GN=TMPO PE=1 SV=2" 6.47 2925 - 738749 - - - 0.4511 - 3.559 0.666 - 437.8 1 2 0 0.0011 25 0 0 0 1.91E+07 2.47E+07 - - - 8.8855 0.9999 221125_WJC_METTL3_EV_vs_WT_F08.17085.17085.3 3.57E-06 15/56 R.STSHK[136.11]PDEIYGMIER[166.11].L sp|Q86U44|MTA70_HUMAN 1 1779.8581 0.14 119880 17085 3 1779.860098 594.2933 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 5.42 2925.3 - 604398 - - - 1.1484 - 2.919 0.359 - 308 1 2 0 0.002 15 0 0 0 4.13E+06 3.01E+07 - - - 5.3372 1 221125_WJC_METTL3_EV_vs_WT_F08.17087.17087.3 4.50E-09 Dec-80 K.LLTQHENIKNEIDNYEEDYQK.M "sp|Q01082|SPTB2_HUMAN,tr|A0A087WUZ3|A0A087WUZ3_HUMAN" 2 2635.2402 1.43 119882 17087 3 2635.240291 879.4207 "Spectrin beta chain, non-erythrocytic 1 OS=Homo sapiens OX=9606 GN=SPTBN1 PE=1 SV=2" 4.35 2925.6 - 220904 - - - 0.0379 - 3.141 0.675 - 166.6 1 2 1 0.0001 21 0 0 0 1.84E+07 1.29E+07 - - - 8.8095 0.9845 221125_WJC_METTL3_EV_vs_WT_F08.17088.17088.3 0.0692 Jun-36 R.MVNHFIAEFK[136.11].R "sp|P11142|HSP7C_HUMAN,tr|A8K7Q2|A8K7Q2_HUMAN,tr|E9PKE3|E9PKE3_HUMAN,tr|E9PN89|E9PN89_HUMAN" 4 1242.6311 0.13 119883 17088 3 1242.63416 415.2176 Heat shock cognate 71 kDa protein OS=Homo sapiens OX=9606 GN=HSPA8 PE=1 SV=1 6.5 2925.7 - 152901 - - - 2.4907 - 1.282 0.258 - 58.5 1 2 0 0.0031 10 0 0 0 1.07E+06 8.24E+06 - - - 2.1411 1 221125_WJC_METTL3_EV_vs_WT_F08.17095.17095.4 7.00E-05 15/162 R.GPNGASAGVAAQHSQC[160.03]FAAWYGHC[160.03]PGLK[136.11].V "sp|P11177|ODPB_HUMAN,tr|F8WF02|F8WF02_HUMAN,tr|C9J634|C9J634_HUMAN" 3 2906.3221 1.32 119888 17095 4 2906.32213 727.5878 "Pyruvate dehydrogenase E1 component subunit beta, mitochondrial OS=Homo sapiens OX=9606 GN=PDHB PE=1 SV=3" 8.06 2926.6 - 354522 - - - 0.0272 - 2.54 0.509 - 109.6 1 2 0 0.0001 28 0 0 0 6.63E+06 5.04E+06 - - - 3.9457 0.9876 221125_WJC_METTL3_EV_vs_WT_F08.17098.17098.4 0.0531 10/108 R.GLLQDDAHPTLVTYADHSK[136.11].L "sp|Q86U44|MTA70_HUMAN,tr|F5H6D8|F5H6D8_HUMAN,tr|H0YFV6|H0YFV6_HUMAN,tr|B4DTN4|B4DTN4_HUMAN" 4 2088.0367 0.12 119891 17098 4 2089.039033 523.0165 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 5.13 2927 - 179590 - - - 480.0203 - 2.094 0.357 - 102.5 1 2 0 1.0023 19 0 0 0 1.08E+06 9.27E+06 - - - 2.3057 0.9999 221125_WJC_METTL3_EV_vs_WT_F08.17101.17101.4 8.62E-05 17/120 K.QSGEPFLQDGSC[160.03]INVAPHLHK[136.11].C sp|Q7LBC6|KDM3B_HUMAN 1 2341.1365 1.72 119892 17101 4 2341.14204 586.2914 Lysine-specific demethylase 3B OS=Homo sapiens OX=9606 GN=KDM3B PE=1 SV=2 5.99 2927.4 - 450228 - - - 2.3813 - 3.301 0.486 - 224.1 1 2 0 0.0056 21 0 0 0 1.58E+07 9.23E+06 - - - 3.8495 0.9997 221125_WJC_METTL3_EV_vs_WT_F08.17103.17103.4 3.72E-11 18/144 K.VINAAHSFYNGTTTLPISDEDRTPR.K sp|P49915|GUAA_HUMAN 1 2774.3624 1.2 119894 17103 4 2774.370672 694.5979 GMP synthase [glutamine-hydrolyzing] OS=Homo sapiens OX=9606 GN=GMPS PE=1 SV=1 5.38 2927.7 - 483319 - - - 2.992 - 3.782 0.526 - 105.5 1 2 1 0.0083 25 0 0 0 5.16E+06 4.30E+06 - - - 4.2252 1 221125_WJC_METTL3_EV_vs_WT_F08.17105.17105.3 1.20E-11 21/104 R.GGYDGYR[166.11]PSFSNTPNSGYTQSQFSAPR[166.11].D "sp|Q14444|CAPR1_HUMAN,tr|G3V153|G3V153_HUMAN" 2 2960.3229 1.09 119896 17105 3 2960.329858 987.7816 Caprin-1 OS=Homo sapiens OX=9606 GN=CAPRIN1 PE=1 SV=2 8.5 2927.9 - 389302 - - - 2.3663 - 4.275 0.759 - 483.7 1 2 0 0.007 27 0 0 0 2.58E+07 2.37E+07 - - - 10.3425 1 221125_WJC_METTL3_EV_vs_WT_F08.17110.17110.3 1.90E-07 18/104 R.GGYDGYRPSFSNTPNSGYTQSQFSAPR.D "sp|Q14444|CAPR1_HUMAN,tr|G3V153|G3V153_HUMAN" 2 2940.3063 1.09 119898 17110 3 2940.304875 981.1094 Caprin-1 OS=Homo sapiens OX=9606 GN=CAPRIN1 PE=1 SV=2 8.5 2928.6 - 565341 - - - -0.4891 - 3.962 0.697 - 394.5 1 2 0 -0.0014 27 0 0 0 2.58E+07 2.37E+07 - - - 9.4779 0.9999 221125_WJC_METTL3_EV_vs_WT_F08.17111.17111.3 0.000106 Sep-52 K.K[136.11]GPGEVAGTVTGQK[136.11].R "sp|Q86U44|MTA70_HUMAN,tr|F5H6D8|F5H6D8_HUMAN,tr|H0YFV6|H0YFV6_HUMAN,tr|B4DTN4|B4DTN4_HUMAN" 4 1343.738 0.03 119899 17111 3 1343.739572 448.9199 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 8.59 2928.7 - 238481 - - - 1.1855 - 2.213 0.416 - 131 1 2 0 0.0016 14 0 0 0 2.19E+05 7.30E+06 - - - 5.2886 0.9996 221125_WJC_METTL3_EV_vs_WT_F08.17116.17116.4 1.36E-06 19/102 K.EGQEEVLKEVVESEGERK.T "sp|Q8TAQ2|SMRC2_HUMAN,tr|F8VXC8|F8VXC8_HUMAN" 2 2073.0226 6.3 119902 17116 4 2073.028234 519.2629 SWI\SNF complex subunit SMARCC2 OS=Homo sapiens OX=9606 GN=SMARCC2 PE=1 SV=1 4.36 2929.4 - 518624 - - - 2.7211 - 2.882 0.487 - 208.5 1 2 1 0.0056 18 0 0 0 1.50E+07 2.38E+06 - - - 3.8259 1 221125_WJC_METTL3_EV_vs_WT_F08.17120.17120.4 2.38E-07 19/126 K.KPDYLPYAEDESVDDLAQQKPR.S sp|O43290|SNUT1_HUMAN 1 2576.2395 6.96 119906 17120 4 2576.240448 645.0671 U4\U6.U5 tri-snRNP-associated protein 1 OS=Homo sapiens OX=9606 GN=SART1 PE=1 SV=1 4.23 2929.9 - 254264 - - - 0.3827 - 3.463 0.571 - 256.1 1 2 0 0.001 22 0 0 0 7.92E+06 1.14E+06 - - - 4.6021 0.9998 221125_WJC_METTL3_EV_vs_WT_F08.17123.17123.4 9.61E-06 10/162 R.LPLQLDDAVRPEAEGEEEGRATVNQDTR.L "sp|P14868|SYDC_HUMAN,tr|C9J7S3|C9J7S3_HUMAN,tr|C9JLC1|C9JLC1_HUMAN" 3 3107.5119 0.8 119907 17123 4 3107.516556 777.8853 "Aspartate--tRNA ligase, cytoplasmic OS=Homo sapiens OX=9606 GN=DARS1 PE=1 SV=2" 4.12 2930.3 - 204999 - - - 1.4825 - 1.972 0.492 - 39.2 1 2 1 0.0046 28 0 0 0 6.60E+06 8.26E+06 - - - 3.7179 0.9998 221125_WJC_METTL3_EV_vs_WT_F08.17126.17126.4 0.00029 16/162 R.LPLQLDDAVR[166.11]PEAEGEEEGR[166.11]ATVNQDTR[166.11].L "sp|P14868|SYDC_HUMAN,tr|C9J7S3|C9J7S3_HUMAN,tr|C9JLC1|C9JLC1_HUMAN" 3 3137.5368 0.81 119910 17126 4 3137.54271 785.3915 "Aspartate--tRNA ligase, cytoplasmic OS=Homo sapiens OX=9606 GN=DARS1 PE=1 SV=2" 4.12 2930.7 - 350431 - - - 1.8967 - 2.57 0.531 - 104.4 1 2 1 0.006 28 0 0 0 6.66E+06 8.26E+06 - - - 4.1392 0.9991 221125_WJC_METTL3_EV_vs_WT_F08.17127.17127.3 0.000769 Jul-80 K.QSGEPFLQDGSC[160.03]INVAPHLHK[136.11].C sp|Q7LBC6|KDM3B_HUMAN 1 2341.1365 3.51 119911 17127 3 2341.132186 781.3861 Lysine-specific demethylase 3B OS=Homo sapiens OX=9606 GN=KDM3B PE=1 SV=2 5.99 2930.8 - 173916 - - - -1.8277 - 1.67 0.359 - 37.8 1 2 0 -0.0043 21 0 0 0 7.41E+06 2.11E+06 - - - 3.7708 1 221125_WJC_METTL3_EV_vs_WT_F08.17135.17135.3 6.03E-09 16/104 K.DSTGAADPPQPHIVGIQSPDQQAALAR.H "sp|Q9BQ95|ECSIT_HUMAN,tr|J3KTF5|J3KTF5_HUMAN" 2 2739.3576 1.29 119917 17135 3 2739.363314 914.1265 "Evolutionarily conserved signaling intermediate in Toll pathway, mitochondrial OS=Homo sapiens OX=9606 GN=ECSIT PE=1 SV=1" 4.41 2931.7 - 251567 - - - 2.0786 - 3.15 0.638 - 117.7 1 2 0 0.0057 27 0 0 0 5.25E+06 4.08E+06 - - - 8.2912 1 221125_WJC_METTL3_EV_vs_WT_F08.17136.17136.3 5.09E-12 18/104 K.DSTGAADPPQPHIVGIQSPDQQAALAR[166.11].H "sp|Q9BQ95|ECSIT_HUMAN,tr|J3KTF5|J3KTF5_HUMAN" 2 2749.3659 1.29 119918 17136 3 2749.368829 917.4626 "Evolutionarily conserved signaling intermediate in Toll pathway, mitochondrial OS=Homo sapiens OX=9606 GN=ECSIT PE=1 SV=1" 4.41 2931.9 - 225604 - - - 1.069 - 3.118 0.646 - 129.5 1 2 0 0.0029 27 0 0 0 5.25E+06 4.08E+06 - - - 8.3577 0.9999 221125_WJC_METTL3_EV_vs_WT_F08.17141.17141.4 1.14E-07 17/120 K.QSGEPFLQDGSC[160.03]INVAPHLHK.C sp|Q7LBC6|KDM3B_HUMAN 1 2333.1223 1.73 119922 17141 4 2333.129347 584.2878 Lysine-specific demethylase 3B OS=Homo sapiens OX=9606 GN=KDM3B PE=1 SV=2 5.99 2932.5 - 765381 - - - 3.0354 - 2.913 0.559 - 217.8 1 2 0 0.0071 21 0 0 0 1.71E+07 9.91E+06 - - - 4.4431 1 221125_WJC_METTL3_EV_vs_WT_F08.17142.17142.4 5.56E-07 13/78 K.HWPFQVINDGDKPK.V "sp|P0DMV8|HS71A_HUMAN,sp|P0DMV9|HS71B_HUMAN,tr|A0A0G2JIW1|A0A0G2JIW1_HUMAN" 3 1679.842 0.13 119923 17142 4 1679.845017 420.9678 Heat shock 70 kDa protein 1A OS=Homo sapiens OX=9606 GN=HSPA1A PE=1 SV=1 6.75 2932.6 - 266126 - - - 1.802 - 2.798 0.536 - 101.1 1 2 0 0.003 14 0 0 0 3.17E+07 2.35E+08 - - - 4.265 0.9864 221125_WJC_METTL3_EV_vs_WT_F08.17146.17146.3 0.577 Jun-76 R.LK[136.11]ETIDNNSVSSPLQSLQQR[166.11].T "sp|P60228|EIF3E_HUMAN,tr|A0A7I2V3I2|A0A7I2V3I2_HUMAN,tr|H0YBP5|H0YBP5_HUMAN,tr|A0A7I2V5Z6|A0A7I2V5Z6_HUMAN,tr|A0A7I2V2H9|A0A7I2V2H9_HUMAN,tr|B3KW56|B3KW56_HUMAN,tr|A0A7I2V4B4|A0A7I2V4B4_HUMAN,tr|E5RGA2|E5RGA2_HUMAN,tr|A0A7I2V3I0|A0A7I2V3I0_HUMAN,tr|A0A7I2V3S3|A0A7I2V3S3_HUMAN,tr|A0A7I2V4G3|A0A7I2V4G3_HUMAN,tr|E5RHS5|E5RHS5_HUMAN,tr|A0A7I2V2W0|A0A7I2V2W0_HUMAN,tr|A0A7I2V5P9|A0A7I2V5P9_HUMAN" 14 2274.1935 2.29 119927 17146 3 2274.191544 759.0718 Eukaryotic translation initiation factor 3 subunit E OS=Homo sapiens OX=9606 GN=EIF3E PE=1 SV=1 6.07 2933.1 - 177819 - - - -0.8421 - 1.956 0.215 - 37.1 1 2 1 -0.0019 20 0 0 0 6.89E+06 3.01E+06 - - - 2.5641 0.9996 221125_WJC_METTL3_EV_vs_WT_F08.17153.17153.4 0.000496 17/144 R.NQLSTAASLGPSGLQNHGQHLILSR[166.11].E "sp|Q96JN0|LCOR_HUMAN,tr|A0A6Q8PH28|A0A6Q8PH28_HUMAN,tr|A0A6Q8PG83|A0A6Q8PG83_HUMAN,tr|A0A6Q8PFQ9|A0A6Q8PFQ9_HUMAN,tr|A0A6Q8PGR8|A0A6Q8PGR8_HUMAN,tr|A0A6Q8PGL8|A0A6Q8PGL8_HUMAN,tr|A0A6Q8PFM9|A0A6Q8PFM9_HUMAN" 7 2608.3709 2.56 119932 17153 4 2608.381123 653.1 Ligand-dependent corepressor OS=Homo sapiens OX=9606 GN=LCOR PE=1 SV=2 9.76 2934 - 320287 - - - 3.9132 - 3.558 0.444 - 186.9 1 2 0 0.0102 25 0 0 0 6.55E+06 2.56E+06 - - - 3.4915 1 221125_WJC_METTL3_EV_vs_WT_F08.17158.17158.4 3.68E-11 21/102 R.NNQGQLIAEPFYHLPSKK.K "sp|Q86U86|PB1_HUMAN,tr|H0Y5B5|H0Y5B5_HUMAN,tr|E7EVG2|E7EVG2_HUMAN" 3 2083.0851 1.77 119935 17158 4 2083.088727 521.7785 Protein polybromo-1 OS=Homo sapiens OX=9606 GN=PBRM1 PE=1 SV=1 8.51 2934.7 - 629152 - - - 1.7536 - 3.548 0.579 - 346.6 1 2 0 0.0037 18 0 0 0 2.22E+07 1.25E+07 - - - 4.6984 0.9999 221125_WJC_METTL3_EV_vs_WT_F08.17162.17162.3 1.49E-06 19/52 K.HWPFQVINDGDK[136.11]PK[136.11].V "sp|P0DMV8|HS71A_HUMAN,sp|P0DMV9|HS71B_HUMAN,tr|A0A0G2JIW1|A0A0G2JIW1_HUMAN" 3 1695.8704 0.13 119938 17162 3 1695.876631 566.2974 Heat shock 70 kDa protein 1A OS=Homo sapiens OX=9606 GN=HSPA1A PE=1 SV=1 6.75 2935.2 - 4.68E+06 - - - 3.6801 - 3.082 0.568 - 689.2 1 2 0 0.0062 14 0 0 0 1.15E+08 8.67E+08 - - - 7.8622 0.9999 221125_WJC_METTL3_EV_vs_WT_F08.17164.17164.4 3.35E-10 18/96 R.RSDEDYLYREELAQFHR.D "sp|P16435|NCPR_HUMAN,tr|H0Y4R2|H0Y4R2_HUMAN,tr|E7EMD0|E7EMD0_HUMAN" 3 2226.0454 0.96 119939 17164 4 2226.050518 557.5186 NADPH--cytochrome P450 reductase OS=Homo sapiens OX=9606 GN=POR PE=1 SV=2 4.9 2935.4 - 680462 - - - 2.3018 - 3.388 0.584 - 294.1 1 2 1 0.0051 17 0 0 0 5.79E+06 6.04E+06 - - - 4.7314 0.9998 221125_WJC_METTL3_EV_vs_WT_F08.17171.17171.4 1.58E-06 18/102 R.NNQGQLIAEPFYHLPSK[136.11]K[136.11].K "sp|Q86U86|PB1_HUMAN,tr|H0Y5B5|H0Y5B5_HUMAN,tr|E7EVG2|E7EVG2_HUMAN" 3 2099.1135 1.77 119944 17171 4 2099.121035 525.7856 Protein polybromo-1 OS=Homo sapiens OX=9606 GN=PBRM1 PE=1 SV=1 8.51 2936.3 - 877160 - - - 3.602 - 3.187 0.473 - 242 1 2 0 0.0076 18 0 0 0 2.22E+07 1.25E+07 - - - 3.7379 0.9995 221125_WJC_METTL3_EV_vs_WT_F08.17173.17173.3 4.95E-07 Dec-76 R.STANNVEIHIPVPNDADSPK.F "sp|Q9BXS5|AP1M1_HUMAN,tr|K7EJL1|K7EJL1_HUMAN,tr|K7EQX3|K7EQX3_HUMAN" 3 2117.0389 0.93 119946 17173 3 2117.051341 706.6869 AP-1 complex subunit mu-1 OS=Homo sapiens OX=9606 GN=AP1M1 PE=1 SV=3 4.53 2936.6 - 397178 - - - 5.8709 - 2.762 0.567 - 112.1 1 2 0 0.0124 20 0 0 0 3.02E+07 3.26E+07 - - - 7.3228 1 221125_WJC_METTL3_EV_vs_WT_F08.17174.17174.4 3.42E-10 20/90 R.R[166.11]GFC[160.03]FITYTDEEPVK[136.11]K[136.11].L "sp|O14979|HNRDL_HUMAN,tr|A0A087WUK2|A0A087WUK2_HUMAN" 2 2015.0033 1.01 119947 17174 4 2015.009395 504.7581 Heterogeneous nuclear ribonucleoprotein D-like OS=Homo sapiens OX=9606 GN=HNRNPDL PE=1 SV=3 6.17 2936.7 - 369892 - - - 3.0402 - 3.074 0.631 - 323.7 1 2 0 0.0061 16 0 0 0 5.83E+06 5.77E+06 - - - 5.1121 0.9996 221125_WJC_METTL3_EV_vs_WT_F08.17177.17177.3 3.47E-06 15/88 R.KVGNPFELDTQQGPQVDKEQFER.V sp|P30837|AL1B1_HUMAN 1 2688.3144 2.84 119950 17177 3 2688.324824 897.1121 "Aldehyde dehydrogenase X, mitochondrial OS=Homo sapiens OX=9606 GN=ALDH1B1 PE=1 SV=3" 4.51 2937.1 - 201584 - - - 3.8928 - 3.245 0.609 - 179.6 1 2 1 0.0105 23 0 0 0 2.52E+06 8.86E+05 - - - 8.0883 1 221125_WJC_METTL3_EV_vs_WT_F08.17183.17183.4 8.85E-08 12/198 K.FPSTETATLAQKPSQDTEKPLEPVSTVQVEPAVK.T "sp|Q9Y520|PRC2C_HUMAN,tr|E7EPN9|E7EPN9_HUMAN" 2 3651.8883 1.1 119954 17183 4 3651.894836 913.9794 Protein PRRC2C OS=Homo sapiens OX=9606 GN=PRRC2C PE=1 SV=4 4.59 2937.9 - 331142 - - - 1.7794 - 2.786 0.578 - 24 1 2 0 0.0065 34 0 0 0 6.77E+06 6.18E+06 - - - 4.5607 0.9999 221125_WJC_METTL3_EV_vs_WT_F08.17184.17184.3 1.64E-05 21/68 R.NNQGQLIAEPFYHLPSKK.K "sp|Q86U86|PB1_HUMAN,tr|H0Y5B5|H0Y5B5_HUMAN,tr|E7EVG2|E7EVG2_HUMAN" 3 2083.0851 1.66 119955 17184 3 2083.090901 695.369 Protein polybromo-1 OS=Homo sapiens OX=9606 GN=PBRM1 PE=1 SV=1 8.51 2938 - 534002 - - - 2.7973 - 3.139 0.447 - 577.4 1 2 0 0.0058 18 0 0 0 5.75E+06 3.47E+06 - - - 6.3704 0.8408 221125_WJC_METTL3_EV_vs_WT_F08.17193.17193.3 3.81E-05 18/72 K.SKELTTEIDNNIEQISSYK.S "sp|P13645|K1C10_HUMAN,tr|A0A1B0GVI3|A0A1B0GVI3_HUMAN" 2 2211.0907 24.64 119962 17193 3 2212.084139 738.0375 "Keratin, type I cytoskeletal 10 OS=Homo sapiens OX=9606 GN=KRT10 PE=1 SV=6" 4.41 2939.2 - 1.57E+06 - - - 449.3104 - 2.995 0.358 - 401.8 1 2 1 0.9935 19 0 0 0 9.01E+06 3.66E+05 - - - 4.9511 1 221125_WJC_METTL3_EV_vs_WT_F08.17198.17198.4 2.49E-13 24/120 R.IC[160.03]NAVSPDK[136.11]DVDGFHVINVGR[166.11].M "sp|P13995|MTDC_HUMAN,tr|A0A7I2V482|A0A7I2V482_HUMAN,tr|A0A7I2V2U6|A0A7I2V2U6_HUMAN,tr|A0A7I2YQD4|A0A7I2YQD4_HUMAN,tr|B8ZZU9|B8ZZU9_HUMAN" 5 2329.1604 1.23 119967 17198 4 2329.170539 583.2974 "Bifunctional methylenetetrahydrofolate dehydrogenase\cyclohydrolase, mitochondrial OS=Homo sapiens OX=9606 GN=MTHFD2 PE=1 SV=2" 5.3 2939.9 - 240319 - - - 4.3595 - 3.655 0.638 - 127.9 1 2 1 0.0102 21 0 0 0 1.32E+07 1.07E+07 - - - 5.2049 0.9998 221125_WJC_METTL3_EV_vs_WT_F08.17202.17202.4 2.14E-08 20/120 R.IC[160.03]NAVSPDKDVDGFHVINVGR.M "sp|P13995|MTDC_HUMAN,tr|A0A7I2V482|A0A7I2V482_HUMAN,tr|A0A7I2V2U6|A0A7I2V2U6_HUMAN,tr|A0A7I2YQD4|A0A7I2YQD4_HUMAN,tr|B8ZZU9|B8ZZU9_HUMAN" 5 2311.1379 1.23 119969 17202 4 2311.144061 578.7918 "Bifunctional methylenetetrahydrofolate dehydrogenase\cyclohydrolase, mitochondrial OS=Homo sapiens OX=9606 GN=MTHFD2 PE=1 SV=2" 5.3 2940.3 - 425268 - - - 2.6593 - 3.25 0.532 - 136.7 1 2 1 0.0061 21 0 0 0 1.32E+07 1.07E+07 - - - 4.2445 0.9991 221125_WJC_METTL3_EV_vs_WT_F08.17205.17205.4 0.00177 10/120 K.NLDAVHDITVAYPHNIPQSEK.H sp|Q6UWP7|LCLT1_HUMAN 1 2360.1761 0.72 119972 17205 4 2360.180104 591.0513 Lysocardiolipin acyltransferase 1 OS=Homo sapiens OX=9606 GN=LCLAT1 PE=1 SV=1 5.21 2940.7 - 331083 - - - 1.7075 - 2.176 0.317 - 52.8 1 2 0 0.004 21 0 0 0 4.77E+06 6.65E+06 - - - 2.2411 1 221125_WJC_METTL3_EV_vs_WT_F08.17206.17206.3 1.45E-07 17/84 K.SGTTSESGALSLEPSHIGDLQK[136.11].A sp|Q7Z417|NUFP2_HUMAN 1 2221.0954 6.31 119973 17206 3 2221.096973 741.3724 Nuclear fragile X mental retardation-interacting protein 2 OS=Homo sapiens OX=9606 GN=NUFIP2 PE=1 SV=1 4.65 2940.8 - 315056 - - - 0.7213 - 3.506 0.569 - 234.2 1 2 0 0.0016 22 0 0 0 2.23E+07 3.54E+06 - - - 7.8575 0.9998 221125_WJC_METTL3_EV_vs_WT_F08.17207.17207.4 5.81E-09 17/156 K.EATPVVHETEPESGSQPR[166.11]PAVLSGYFK[136.11].Q "sp|Q9Y520|PRC2C_HUMAN,tr|E7EPN9|E7EPN9_HUMAN" 2 2929.4577 1.22 119974 17207 4 2929.471126 733.3717 Protein PRRC2C OS=Homo sapiens OX=9606 GN=PRRC2C PE=1 SV=4 4.91 2941 - 276131 - - - 4.5927 - 3.179 0.568 - 146.2 1 2 0 0.0135 27 0 0 0 5.65E+07 4.62E+07 - - - 4.528 0.9999 221125_WJC_METTL3_EV_vs_WT_F08.17214.17214.4 1.09E-08 22/156 K.EATPVVHETEPESGSQPRPAVLSGYFK.Q "sp|Q9Y520|PRC2C_HUMAN,tr|E7EPN9|E7EPN9_HUMAN" 2 2911.4352 1.22 119979 17214 4 2911.441823 728.8661 Protein PRRC2C OS=Homo sapiens OX=9606 GN=PRRC2C PE=1 SV=4 4.91 2941.9 - 752060 - - - 2.2741 - 3.454 0.498 - 233.2 1 2 0 0.0066 27 0 0 0 5.64E+07 4.62E+07 - - - 3.9466 0.9997 221125_WJC_METTL3_EV_vs_WT_F08.17215.17215.3 0.000242 14/84 R.GTGNTSTDGSYK[136.11]PSFLTDQELK[136.11].H "sp|P27540|ARNT_HUMAN,tr|A6NGV6|A6NGV6_HUMAN" 2 2361.1307 0.18 119980 17215 3 2361.137589 788.0508 Aryl hydrocarbon receptor nuclear translocator OS=Homo sapiens OX=9606 GN=ARNT PE=1 SV=1 4.56 2942 - 388053 - - - 2.9177 - 2.482 0.415 - 136.7 1 2 0 0.0069 22 0 0 0 7.83E+05 4.47E+06 - - - 5.3202 0.998 221125_WJC_METTL3_EV_vs_WT_F08.17219.17219.4 0.0043 Aug-90 R.DLKPENILLDDHGHIR.L "sp|P43250|GRK6_HUMAN,tr|D6RHX8|D6RHX8_HUMAN,tr|F8W9W2|F8W9W2_HUMAN" 3 1883.9854 1.02 119984 17219 4 1883.99171 472.0036 G protein-coupled receptor kinase 6 OS=Homo sapiens OX=9606 GN=GRK6 PE=1 SV=2 5.26 2942.5 - 200080 - - - 3.3705 - 2.216 0.328 - 55.7 1 2 0 0.0063 16 0 0 0 2.09E+06 2.05E+06 - - - 2.3594 0.9971 221125_WJC_METTL3_EV_vs_WT_F08.17221.17221.3 0.0252 Jul-32 K.FYVHNDIFR.Y "sp|Q13283|G3BP1_HUMAN,tr|A0A7I2V5M7|A0A7I2V5M7_HUMAN,tr|A0A7P0P2U7|A0A7P0P2U7_HUMAN,tr|A0A7I2YQU8|A0A7I2YQU8_HUMAN,tr|A0A7I2V651|A0A7I2V651_HUMAN,tr|A0A7I2YQN9|A0A7I2YQN9_HUMAN,tr|A0A7I2V2V1|A0A7I2V2V1_HUMAN" 7 1209.5931 0.62 119985 17221 3 1209.595217 404.205 Ras GTPase-activating protein-binding protein 1 OS=Homo sapiens OX=9606 GN=G3BP1 PE=1 SV=1 6.74 2942.8 - 91346.4 - - - 1.756 - 1.495 0.285 - 60.5 1 2 0 0.0021 9 0 0 0 1.65E+06 2.68E+06 - - - 2.9288 0.9922 221125_WJC_METTL3_EV_vs_WT_F08.17224.17224.3 8.07E-05 11/104 K.ALGSDC[160.03]GGSSGSSSGSGPSAPTSSSVL.G sp|Q96F45|ZN503_HUMAN 1 2355.0132 - 119986 17224 3 2355.012249 786.0117 Zinc finger protein 503 OS=Homo sapiens OX=9606 GN=ZNF503 PE=1 SV=1 3.8 2943.2 - 494700 - - - -0.4153 - 2.233 0.457 - 93.2 1 1 0 -0.001 27 0 0 0 - - - - - 5.483 0.9992 221125_WJC_METTL3_EV_vs_WT_F08.17227.17227.3 0.00651 Aug-32 K.FYVHNDIFR[166.11].Y "sp|Q13283|G3BP1_HUMAN,tr|A0A7I2V5M7|A0A7I2V5M7_HUMAN,tr|A0A7P0P2U7|A0A7P0P2U7_HUMAN,tr|A0A7I2YQU8|A0A7I2YQU8_HUMAN,tr|A0A7I2V651|A0A7I2V651_HUMAN,tr|A0A7I2YQN9|A0A7I2YQN9_HUMAN,tr|A0A7I2V2V1|A0A7I2V2V1_HUMAN" 7 1219.6014 0.51 119989 17227 3 1219.6029 407.5411 Ras GTPase-activating protein-binding protein 1 OS=Homo sapiens OX=9606 GN=G3BP1 PE=1 SV=1 6.74 2943.6 - 134124 - - - 1.2602 - 1.486 0.35 - 84.7 1 2 0 0.0015 9 0 0 0 1.67E+06 3.27E+06 - - - 3.6355 0.9996 221125_WJC_METTL3_EV_vs_WT_F08.17235.17235.3 7.50E-07 13/80 R.IC[160.03]NAVSPDK[136.11]DVDGFHVINVGR[166.11].M "sp|P13995|MTDC_HUMAN,tr|A0A7I2V482|A0A7I2V482_HUMAN,tr|A0A7I2V2U6|A0A7I2V2U6_HUMAN,tr|A0A7I2YQD4|A0A7I2YQD4_HUMAN,tr|B8ZZU9|B8ZZU9_HUMAN" 5 2329.1604 1.34 119995 17235 3 2329.168996 777.3941 "Bifunctional methylenetetrahydrofolate dehydrogenase\cyclohydrolase, mitochondrial OS=Homo sapiens OX=9606 GN=MTHFD2 PE=1 SV=2" 5.3 2944.7 - 209261 - - - 3.697 - 3.194 0.565 - 99.4 1 2 1 0.0086 21 0 0 0 2.05E+06 1.53E+06 - - - 7.6209 0.8371 221125_WJC_METTL3_EV_vs_WT_F08.17237.17237.3 0.201 Jun-40 K.GKPLALVEEIR.N "sp|Q9BSD7|NTPCR_HUMAN,tr|Q5TDF0|Q5TDF0_HUMAN" 2 1223.7238 1.12 119997 17237 3 1223.723768 408.9152 Cancer-related nucleoside-triphosphatase OS=Homo sapiens OX=9606 GN=NTPCR PE=1 SV=1 6.14 2944.9 - 126928 - - - -0.0033 - 1.483 0.056 - 55 2 2 0 0 11 0 0 0 1.54E+06 1.37E+06 - - - 0.1445 1 221125_WJC_METTL3_EV_vs_WT_F08.17242.17242.3 0.000195 18/76 R.STANNVEIHIPVPNDADSPK[136.11].F "sp|Q9BXS5|AP1M1_HUMAN,tr|K7EJL1|K7EJL1_HUMAN,tr|K7EQX3|K7EQX3_HUMAN" 3 2125.0531 1.15 120000 17242 3 2125.054181 709.3583 AP-1 complex subunit mu-1 OS=Homo sapiens OX=9606 GN=AP1M1 PE=1 SV=3 4.53 2945.6 - 877389 - - - 0.503 - 2.865 0.453 - 285 1 2 0 0.0011 20 0 0 0 2.38E+07 2.06E+07 - - - 6.1438 1 221125_WJC_METTL3_EV_vs_WT_F08.17247.17247.4 2.45E-12 28/150 R.TPGHPPPPEIPSELGAC[160.03]DFEK[136.11]PESPR[166.11].A "sp|Q92538|GBF1_HUMAN,tr|A0A7I2YQM2|A0A7I2YQM2_HUMAN,tr|A0A669KBG8|A0A669KBG8_HUMAN,tr|A0A7I2V2L5|A0A7I2V2L5_HUMAN,tr|A0A7I2V514|A0A7I2V514_HUMAN,tr|A0A7I2YQ65|A0A7I2YQ65_HUMAN,tr|A0A669KB10|A0A669KB10_HUMAN,tr|A0A7I2V452|A0A7I2V452_HUMAN,tr|A0A7P0RGV0|A0A7P0RGV0_HUMAN" 9 2858.3664 2.65 120003 17247 4 2858.368596 715.5989 Golgi-specific brefeldin A-resistance guanine nucleotide exchange factor 1 OS=Homo sapiens OX=9606 GN=GBF1 PE=1 SV=2 4.57 2946.3 - 294222 - - - 0.7634 - 4.501 0.637 - 608.2 1 2 0 0.0022 26 0 0 0 1.32E+07 4.97E+06 - - - 5.2444 1 221125_WJC_METTL3_EV_vs_WT_F08.17248.17248.3 1.45E-12 22/108 R.KSEATPSPGAC[160.03]LQPEVPLSPAEQATTVK.A "sp|Q2NL68|PRSR3_HUMAN,tr|A0A2R8Y8D9|A0A2R8Y8D9_HUMAN" 2 2892.4539 6.05 120004 17248 3 2892.457869 965.1586 Proline and serine-rich protein 3 OS=Homo sapiens OX=9606 GN=PROSER3 PE=1 SV=1 4.79 2946.4 - 374610 - - - 1.376 - 3.547 0.666 - 310.8 1 2 0 0.004 28 0 0 0 1.12E+07 1.84E+06 - - - 8.877 0.998 221125_WJC_METTL3_EV_vs_WT_F08.17251.17251.4 8.79E-05 12/102 K.FKKPEGSWDC[160.03]ELC[160.03]LVQNK.A sp|P49790|NU153_HUMAN 1 2237.0609 2.07 120007 17251 4 2237.068607 560.2725 Nuclear pore complex protein Nup153 OS=Homo sapiens OX=9606 GN=NUP153 PE=1 SV=2 6.17 2946.8 - 382924 - - - 3.4407 - 2.237 0.415 - 124.8 1 2 1 0.0077 18 0 0 0 2.03E+07 9.78E+06 - - - 3.1118 1 221125_WJC_METTL3_EV_vs_WT_F08.17258.17258.4 2.74E-11 25/108 K.MNLASEPQEVLHIGSAHNR[166.11].S sp|O00151|PDLI1_HUMAN 1 2112.041 0.21 120011 17258 4 2112.045257 529.0175 PDZ and LIM domain protein 1 OS=Homo sapiens OX=9606 GN=PDLIM1 PE=1 SV=4 5.96 2947.7 - 589582 - - - 2.0198 - 4.266 0.634 - 587.5 1 2 0 0.0043 19 0 0 0 2.07E+06 9.75E+06 - - - 5.2339 0.9992 221125_WJC_METTL3_EV_vs_WT_F08.17263.17263.4 0.0057 Sep-96 K.QFTIAK[136.11]PTTHFPLHLSR[166.11].C sp|Q9P0U3|SENP1_HUMAN 1 2011.1122 0.63 120016 17263 4 2011.112268 503.7853 Sentrin-specific protease 1 OS=Homo sapiens OX=9606 GN=SENP1 PE=1 SV=2 11 2948.4 - 138703 - - - 0.0159 - 1.832 0.312 - 39.2 1 2 0 0 17 0 0 0 2.12E+06 3.35E+06 - - - 2.1518 1 221125_WJC_METTL3_EV_vs_WT_F08.17267.17267.3 2.88E-08 28/88 R.GNFGGSFAGSFGGAGGHAPGVAR.K "sp|P52272|HNRPM_HUMAN,tr|M0R2I7|M0R2I7_HUMAN,tr|M0QY96|M0QY96_HUMAN,tr|A0A087X0X3|A0A087X0X3_HUMAN" 4 2033.9456 0.12 120018 17267 3 2033.948143 678.9891 Heterogeneous nuclear ribonucleoprotein M OS=Homo sapiens OX=9606 GN=HNRNPM PE=1 SV=3 9.76 2948.9 - 1.48E+06 - - - 1.2404 - 4.797 0.689 - 789.6 1 2 0 0.0025 23 0 0 0 1.83E+07 1.50E+08 - - - 9.8994 0.9997 221125_WJC_METTL3_EV_vs_WT_F08.17270.17270.4 1.27E-05 18/102 K.FK[136.11]K[136.11]PEGSWDC[160.03]ELC[160.03]LVQNK[136.11].A sp|P49790|NU153_HUMAN 1 2261.1035 2.13 120021 17270 4 2261.10801 566.2832 Nuclear pore complex protein Nup153 OS=Homo sapiens OX=9606 GN=NUP153 PE=1 SV=2 6.17 2949.3 - 532369 - - - 1.9902 - 2.962 0.481 - 321.8 1 2 1 0.0045 18 0 0 0 1.97E+07 9.24E+06 - - - 3.7833 0.9795 221125_WJC_METTL3_EV_vs_WT_F08.17285.17285.4 5.17E-09 23/138 E.VSNRFSGVPDRFSGSGSGTDFTLK.L "sp|A0A075B6S2|KVD29_HUMAN,sp|A0A0A0MRZ7|KVD26_HUMAN" 2 2517.2248 4316.21 120032 17285 4 2517.231521 630.3135 Immunoglobulin kappa variable 2D-29 OS=Homo sapiens OX=9606 GN=IGKV2D-29 PE=3 SV=1 8.72 2951.2 - 3.01E+06 - - - 2.664 - 3.385 0.568 - 242.3 1 1 2 0.0067 24 0 0 0 1.19E+09 2.75E+05 - - - 4.5594 1 221125_WJC_METTL3_EV_vs_WT_F08.17287.17287.4 6.73E-06 15/84 R.STSHK[136.11]PDEIYGMIER[166.11].L sp|Q86U44|MTA70_HUMAN 1 1779.8581 0.01 120034 17287 4 1779.862322 445.9718 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 5.42 2951.5 - 392229 - - - 2.3979 - 2.708 0.545 - 161.9 1 2 0 0.0043 15 0 0 0 1.71E+05 1.97E+07 - - - 4.325 0.9747 221125_WJC_METTL3_EV_vs_WT_F08.17288.17288.3 0.000151 16/92 E.VSNRFSGVPDRFSGSGSGTDFTLK.L "sp|A0A075B6S2|KVD29_HUMAN,sp|A0A0A0MRZ7|KVD26_HUMAN" 2 2517.2248 999 120035 17288 3 2517.228224 840.0822 Immunoglobulin kappa variable 2D-29 OS=Homo sapiens OX=9606 GN=IGKV2D-29 PE=3 SV=1 8.72 2951.6 - 345446 - - - 1.3543 - 2.848 0.464 - 104.4 1 1 2 0.0034 24 0 0 0 2.02E+08 0.00E+00 - - - 6.1431 1 221125_WJC_METTL3_EV_vs_WT_F08.17289.17289.3 2.90E-06 17/64 R.HDGSEPC[160.03]VDVLFGDGHR.L sp|Q96EL3|RM53_HUMAN 1 1895.8221 1.34 120036 17289 3 1895.827868 632.948 "39S ribosomal protein L53, mitochondrial OS=Homo sapiens OX=9606 GN=MRPL53 PE=1 SV=1" 4.64 2951.8 - 986335 - - - 3.0636 - 3.088 0.609 - 325.7 1 2 0 0.0058 17 0 0 0 1.86E+08 1.39E+08 - - - 8.1766 0.9998 221125_WJC_METTL3_EV_vs_WT_F08.17291.17291.4 1.80E-07 20/150 R.TPGHPPPPEIPSELGAC[160.03]DFEKPESPR.A "sp|Q92538|GBF1_HUMAN,tr|A0A7I2YQM2|A0A7I2YQM2_HUMAN,tr|A0A669KBG8|A0A669KBG8_HUMAN,tr|A0A7I2V2L5|A0A7I2V2L5_HUMAN,tr|A0A7I2V514|A0A7I2V514_HUMAN,tr|A0A7I2YQ65|A0A7I2YQ65_HUMAN,tr|A0A669KB10|A0A669KB10_HUMAN,tr|A0A7I2V452|A0A7I2V452_HUMAN,tr|A0A7P0RGV0|A0A7P0RGV0_HUMAN" 9 2840.3439 2.5 120038 17291 4 2840.356198 711.0933 Golgi-specific brefeldin A-resistance guanine nucleotide exchange factor 1 OS=Homo sapiens OX=9606 GN=GBF1 PE=1 SV=2 4.57 2952 - 301009 - - - 4.3143 - 3.315 0.536 - 187 1 2 0 0.0123 26 0 0 0 1.38E+07 5.54E+06 - - - 4.266 0.9955 221125_WJC_METTL3_EV_vs_WT_F08.17292.17292.3 0.0182 Aug-40 K.ALNSIIDVYHK.Y sp|P05109|S10A8_HUMAN 1 1271.6874 128.86 120039 17292 3 1271.690656 424.9031 Protein S100-A8 OS=Homo sapiens OX=9606 GN=S100A8 PE=1 SV=1 6.79 2952.2 - 223686 - - - 2.5706 - 1.749 0.257 - 102.6 1 2 0 0.0033 11 0 0 0 2.72E+06 2.11E+04 - - - 2.9925 1 221125_WJC_METTL3_EV_vs_WT_F08.17296.17296.4 1.45E-06 19/168 K.IQIASESSGIPERPC[160.03]VLTGTPESIEQAKR.L sp|Q96I24|FUBP3_HUMAN 1 3152.6136 1.22 120041 17296 4 3152.62046 789.1607 Far upstream element-binding protein 3 OS=Homo sapiens OX=9606 GN=FUBP3 PE=1 SV=2 4.95 2952.7 - 472365 - - - 2.1833 - 3.518 0.52 - 145.8 1 2 0 0.0069 29 0 0 0 2.37E+06 1.94E+06 - - - 4.1378 0.9998 221125_WJC_METTL3_EV_vs_WT_F08.17297.17297.3 1.36E-10 14/68 K.FKKPEGSWDC[160.03]ELC[160.03]LVQNK.A sp|P49790|NU153_HUMAN 1 2237.0609 1.73 120042 17297 3 2237.067648 746.6942 Nuclear pore complex protein Nup153 OS=Homo sapiens OX=9606 GN=NUP153 PE=1 SV=2 6.17 2952.8 - 463255 - - - 3.012 - 2.862 0.616 - 268.7 1 2 1 0.0067 18 0 0 0 9.55E+06 5.53E+06 - - - 8.0243 1 221125_WJC_METTL3_EV_vs_WT_F08.17298.17298.4 3.24E-11 21/96 R.HDGSEPC[160.03]VDVLFGDGHR[166.11].L sp|Q96EL3|RM53_HUMAN 1 1905.8303 1.35 120043 17298 4 1905.834769 477.4649 "39S ribosomal protein L53, mitochondrial OS=Homo sapiens OX=9606 GN=MRPL53 PE=1 SV=1" 4.64 2953 - 310303 - - - 2.3292 - 3.415 0.656 - 444.1 1 2 0 0.0044 17 0 0 0 9.13E+07 6.78E+07 - - - 5.361 1 221125_WJC_METTL3_EV_vs_WT_F08.17300.17300.3 5.04E-05 15/112 R.AFSTVPLTPVPRPSDSVSSTPAATSTPSK.Q "sp|Q9ULV3|CIZ1_HUMAN,tr|Q5SYW2|Q5SYW2_HUMAN,tr|F5H2X7|F5H2X7_HUMAN,tr|H0Y5D5|H0Y5D5_HUMAN,tr|A0A494C0L7|A0A494C0L7_HUMAN,tr|Q9BTG3|Q9BTG3_HUMAN" 6 2884.4818 4.79 120045 17300 3 2884.485813 962.5012 Cip1-interacting zinc finger protein OS=Homo sapiens OX=9606 GN=CIZ1 PE=1 SV=2 8.79 2953.2 - 245009 - - - 1.385 - 2.615 0.536 - 108.2 1 2 0 0.004 29 0 0 0 7.56E+07 1.58E+07 - - - 6.7263 1 221125_WJC_METTL3_EV_vs_WT_F08.17306.17306.4 8.29E-09 24/168 K.IQIASESSGIPER[166.11]PC[160.03]VLTGTPESIEQAK[136.11]R[166.11].L sp|Q96I24|FUBP3_HUMAN 1 3180.6443 1.81 120049 17306 4 3180.647991 796.1684 Far upstream element-binding protein 3 OS=Homo sapiens OX=9606 GN=FUBP3 PE=1 SV=2 4.95 2954.1 - 610176 - - - 1.1551 - 4.16 0.618 - 261 1 2 0 0.0037 29 0 0 0 1.19E+09 6.59E+08 - - - 5.0434 0.9997 221125_WJC_METTL3_EV_vs_WT_F08.17308.17308.4 0.00219 14/102 K.K[136.11]QGGLGPMNIPLVSDPK[136.11]R[166.11].T "sp|Q06830|PRDX1_HUMAN,tr|A0A0A0MSI0|A0A0A0MSI0_HUMAN" 2 1932.0825 0.66 120051 17308 4 1932.088351 484.0279 Peroxiredoxin-1 OS=Homo sapiens OX=9606 GN=PRDX1 PE=1 SV=1 9.99 2954.3 - 282985 - - - 3.017 - 2.526 0.434 - 152.4 1 2 0 0.0058 18 0 0 0 3.77E+07 5.73E+07 - - - 3.3193 0.999 221125_WJC_METTL3_EV_vs_WT_F08.17310.17310.3 2.51E-07 14/96 K.QGSLINSLKPSGPTPASGQLSSGDK.A "sp|P35658|NU214_HUMAN,tr|A0A0A0MSW3|A0A0A0MSW3_HUMAN,tr|A0A494C1F2|A0A494C1F2_HUMAN,tr|A0A494C104|A0A494C104_HUMAN,tr|H0Y837|H0Y837_HUMAN" 5 2425.2449 3.91 120053 17310 3 2426.24712 809.4222 Nuclear pore complex protein Nup214 OS=Homo sapiens OX=9606 GN=NUP214 PE=1 SV=2 8.59 2954.6 - 155935 - - - 413.2523 - 2.869 0.491 - 142.8 1 2 0 1.0022 25 0 0 0 1.07E+06 2.73E+05 - - - 6.1613 1 221125_WJC_METTL3_EV_vs_WT_F08.17315.17315.3 1.55E-16 27/64 R.HDGSEPC[160.03]VDVLFGDGHR[166.11].L sp|Q96EL3|RM53_HUMAN 1 1905.8303 1.33 120056 17315 3 1905.835436 636.2841 "39S ribosomal protein L53, mitochondrial OS=Homo sapiens OX=9606 GN=MRPL53 PE=1 SV=1" 4.64 2955.3 - 1.47E+06 - - - 2.6791 - 4.361 0.716 - 1316.1 1 2 0 0.0051 17 0 0 0 1.86E+08 1.40E+08 - - - 10.2418 0.9999 221125_WJC_METTL3_EV_vs_WT_F08.17319.17319.4 9.94E-09 15/96 K.HTGFLEISQHSQEFINR.L sp|Q7L0Y3|TM10C_HUMAN 1 2041.997 0.85 120060 17319 4 2042.004311 511.5065 tRNA methyltransferase 10 homolog C OS=Homo sapiens OX=9606 GN=TRMT10C PE=1 SV=2 6 2955.8 - 185503 - - - 3.5867 - 3.198 0.574 - 232.8 1 2 0 0.0073 17 0 0 0 2.63E+06 3.07E+06 - - - 4.6237 1 221125_WJC_METTL3_EV_vs_WT_F08.17327.17327.3 2.53E-07 15/112 R.AFSTVPLTPVPR[166.11]PSDSVSSTPAATSTPSK[136.11].Q "sp|Q9ULV3|CIZ1_HUMAN,tr|Q5SYW2|Q5SYW2_HUMAN,tr|F5H2X7|F5H2X7_HUMAN,tr|H0Y5D5|H0Y5D5_HUMAN,tr|A0A494C0L7|A0A494C0L7_HUMAN,tr|Q9BTG3|Q9BTG3_HUMAN" 6 2902.5043 4.36 120066 17327 3 2902.509105 968.5087 Cip1-interacting zinc finger protein OS=Homo sapiens OX=9606 GN=CIZ1 PE=1 SV=2 8.79 2956.9 - 223318 - - - 1.6596 - 2.722 0.545 - 107.7 1 2 0 0.0048 29 0 0 0 6.88E+07 1.58E+07 - - - 6.9187 0.9998 221125_WJC_METTL3_EV_vs_WT_F08.17331.17331.3 8.17E-06 15/56 R.STSHK[136.11]PDEIYGMIER[166.11].L sp|Q86U44|MTA70_HUMAN 1 1779.8581 0.93 120068 17331 3 1779.860631 594.2933 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 5.42 2957.3 - 533769 - - - 1.4479 - 2.893 0.339 - 295.3 1 2 0 0.0026 15 0 0 0 3.27E+07 3.51E+07 - - - 5.0907 0.9942 221125_WJC_METTL3_EV_vs_WT_F08.17334.17334.4 0.0134 8/108 R.GLLQDDAHPTLVTYADHSK[136.11].L "sp|Q86U44|MTA70_HUMAN,tr|F5H6D8|F5H6D8_HUMAN,tr|H0YFV6|H0YFV6_HUMAN,tr|B4DTN4|B4DTN4_HUMAN" 4 2088.0367 0.03 120071 17334 4 2088.042697 523.0165 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 5.13 2957.7 - 196243 - - - 2.8563 - 1.898 0.266 - 51.1 1 2 0 0.006 19 0 0 0 3.31E+05 1.08E+07 - - - 1.7564 1 221125_WJC_METTL3_EV_vs_WT_F08.17339.17339.3 3.42E-08 16/108 K.VTEWQQTYTYDSGIHSGANTC[160.03]VPSVSSK.G "sp|P14923|PLAK_HUMAN,tr|K7ERP3|K7ERP3_HUMAN,tr|C9JKY1|C9JKY1_HUMAN,tr|C9JK18|C9JK18_HUMAN,tr|C9JTX4|C9JTX4_HUMAN,tr|C9JPI2|C9JPI2_HUMAN,tr|C9J826|C9J826_HUMAN" 7 3101.4036 4.05 120074 17339 3 3101.408881 1034.8085 Junction plakoglobin OS=Homo sapiens OX=9606 GN=JUP PE=1 SV=3 5.32 2958.4 - 294868 - - - 1.6886 - 3.102 0.657 - 152.9 1 2 0 0.0052 28 0 0 0 4.90E+07 1.21E+07 - - - 8.4679 1 221125_WJC_METTL3_EV_vs_WT_F08.17345.17345.3 3.29E-08 15/112 K.IQIASESSGIPER[166.11]PC[160.03]VLTGTPESIEQAK[136.11]R[166.11].L sp|Q96I24|FUBP3_HUMAN 1 3180.6443 2.06 120078 17345 3 3180.64758 1061.222 Far upstream element-binding protein 3 OS=Homo sapiens OX=9606 GN=FUBP3 PE=1 SV=2 4.95 2959.2 - 215361 - - - 1.0259 - 3.257 0.594 - 137.5 1 2 0 0.0033 29 0 0 0 6.69E+07 3.25E+07 - - - 7.8782 1 221125_WJC_METTL3_EV_vs_WT_F08.17350.17350.3 3.52E-08 15/112 K.IQIASESSGIPERPC[160.03]VLTGTPESIEQAKR.L sp|Q96I24|FUBP3_HUMAN 1 3152.6136 2.08 120081 17350 3 3152.616212 1051.8785 Far upstream element-binding protein 3 OS=Homo sapiens OX=9606 GN=FUBP3 PE=1 SV=2 4.95 2959.9 - 566612 - - - 0.8358 - 3.202 0.6 - 108.5 1 2 0 0.0026 29 0 0 0 6.77E+07 3.26E+07 - - - 7.9061 1 221125_WJC_METTL3_EV_vs_WT_F08.17357.17357.4 0.000646 21/108 K.YQQHQESLSAQLQVVYEHR[166.11].S "sp|O00461|GOLI4_HUMAN,tr|F8W785|F8W785_HUMAN" 2 2352.1486 1.21 120085 17357 4 2352.149356 589.0444 Golgi integral membrane protein 4 OS=Homo sapiens OX=9606 GN=GOLIM4 PE=1 SV=1 6 2960.8 - 974658 - - - 0.3099 - 3.421 0.471 - 370.2 1 2 0 0.0007 19 0 0 0 3.11E+07 2.57E+07 - - - 3.7414 1 221125_WJC_METTL3_EV_vs_WT_F08.17364.17364.4 0.000353 20/102 K.R[166.11]PLDDGVGNQLGALVHQR[166.11].T sp|Q96I24|FUBP3_HUMAN 1 1964.0455 1.84 120090 17364 4 1964.044568 492.0187 Far upstream element-binding protein 3 OS=Homo sapiens OX=9606 GN=FUBP3 PE=1 SV=2 6.75 2961.7 - 385975 - - - -0.4725 - 3.775 0.553 - 386 1 2 0 -0.0009 18 0 0 0 2.28E+08 1.24E+08 - - - 4.4941 1 221125_WJC_METTL3_EV_vs_WT_F08.17365.17365.4 4.01E-10 24/102 K.RPLDDGVGNQLGALVHQR.T sp|Q96I24|FUBP3_HUMAN 1 1944.029 1.84 120091 17365 4 1944.027935 487.0145 Far upstream element-binding protein 3 OS=Homo sapiens OX=9606 GN=FUBP3 PE=1 SV=2 6.75 2961.8 - 768642 - - - -0.5252 - 4.173 0.566 - 471.4 1 2 0 -0.001 18 0 0 0 2.30E+08 1.25E+08 - - - 4.6416 1 221125_WJC_METTL3_EV_vs_WT_F08.17372.17372.4 4.27E-07 21/108 K.YQQHQESLSAQLQVVYEHR.S "sp|O00461|GOLI4_HUMAN,tr|F8W785|F8W785_HUMAN" 2 2342.1404 1.21 120095 17372 4 2342.139464 586.5424 Golgi integral membrane protein 4 OS=Homo sapiens OX=9606 GN=GOLIM4 PE=1 SV=1 6 2962.6 - 1.63E+06 - - - -0.3813 - 3.597 0.556 - 358 1 2 0 -0.0009 19 0 0 0 3.11E+07 2.57E+07 - - - 4.4982 1 221125_WJC_METTL3_EV_vs_WT_F08.17377.17377.4 1.44E-08 22/162 K.VTEWQQTYTYDSGIHSGANTC[160.03]VPSVSSK.G "sp|P14923|PLAK_HUMAN,tr|K7ERP3|K7ERP3_HUMAN,tr|C9JKY1|C9JKY1_HUMAN,tr|C9JK18|C9JK18_HUMAN,tr|C9JTX4|C9JTX4_HUMAN,tr|C9JPI2|C9JPI2_HUMAN,tr|C9J826|C9J826_HUMAN" 7 3101.4036 4.13 120099 17377 4 3101.396872 776.3582 Junction plakoglobin OS=Homo sapiens OX=9606 GN=JUP PE=1 SV=3 5.32 2963.2 - 874278 - - - -2.1835 - 4.126 0.592 - 138.2 1 2 0 -0.0068 28 0 0 0 1.63E+07 3.96E+06 - - - 4.8169 1 221125_WJC_METTL3_EV_vs_WT_F08.17378.17378.3 1.46E-10 18/112 K.QKGDTPASATAGDTLSVPAPAVQPEESLK.T "tr|A0A087WYS0|A0A087WYS0_HUMAN,tr|C9J406|C9J406_HUMAN,tr|H7C463|H7C463_HUMAN" 3 2864.4403 1.59 120100 17378 3 2864.437851 955.8207 MICOS complex subunit MIC60 OS=Homo sapiens OX=9606 GN=IMMT PE=1 SV=1 4.32 2963.3 - 623149 - - - -0.8714 - 3.4 0.622 - 143.1 1 2 1 -0.0025 29 0 0 0 8.35E+07 5.24E+07 - - - 8.2895 0.9531 221125_WJC_METTL3_EV_vs_WT_F08.17388.17388.2 0.000531 26-Sep A.SAVPELATDPELEK[136.11].K "sp|Q86U44|MTA70_HUMAN,tr|B4E349|B4E349_HUMAN,tr|F5H6D8|F5H6D8_HUMAN,tr|H0YFV6|H0YFV6_HUMAN,tr|B4DTN4|B4DTN4_HUMAN" 5 1505.7705 0.06 120106 17388 2 1505.767375 753.8925 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 4 2964.6 - 429603 - - - -2.0448 - 1.861 0.372 - 213.3 1 1 0 -0.0031 14 0 0 0 4.80E+06 7.48E+07 - - - 3.3463 0.9992 221125_WJC_METTL3_EV_vs_WT_F08.17389.17389.4 0.0241 11/168 R.AFSTVPLTPVPRPSDSVSSTPAATSTPSK.Q "sp|Q9ULV3|CIZ1_HUMAN,tr|Q5SYW2|Q5SYW2_HUMAN,tr|F5H2X7|F5H2X7_HUMAN,tr|H0Y5D5|H0Y5D5_HUMAN,tr|A0A494C0L7|A0A494C0L7_HUMAN,tr|Q9BTG3|Q9BTG3_HUMAN" 6 2884.4818 13.03 120107 17389 4 2884.479215 722.1277 Cip1-interacting zinc finger protein OS=Homo sapiens OX=9606 GN=CIZ1 PE=1 SV=2 8.79 2964.8 - 356950 - - - -0.9024 - 2.217 0.307 - 35.2 1 2 0 -0.0026 29 0 0 0 7.99E+06 6.14E+05 - - - 2.1428 1 221125_WJC_METTL3_EV_vs_WT_F08.17395.17395.3 3.42E-12 31/68 K.R[166.11]PLDDGVGNQLGALVHQR[166.11].T sp|Q96I24|FUBP3_HUMAN 1 1964.0455 1.91 120111 17395 3 1964.043896 655.6891 Far upstream element-binding protein 3 OS=Homo sapiens OX=9606 GN=FUBP3 PE=1 SV=2 6.75 2965.5 - 2.63E+06 - - - -0.8146 - 5.298 0.592 - 1332.7 1 2 0 -0.0016 18 0 0 0 2.07E+08 1.08E+08 - - - 9.2916 1 221125_WJC_METTL3_EV_vs_WT_F08.17402.17402.3 9.18E-11 20/84 R.SSHLEVSQASQLLQQQQQQQLR[166.11].R "sp|O75376|NCOR1_HUMAN,tr|J3KT44|J3KT44_HUMAN,tr|E7EVU5|E7EVU5_HUMAN,tr|C9JAP0|C9JAP0_HUMAN,tr|J3KS51|J3KS51_HUMAN,tr|E7EW50|E7EW50_HUMAN" 6 2573.3185 1.25 120116 17402 3 2573.303608 858.7801 Nuclear receptor corepressor 1 OS=Homo sapiens OX=9606 GN=NCOR1 PE=1 SV=2 6.47 2966.4 - 409089 - - - -5.805 - 4.487 0.65 - 650.9 1 2 0 -0.0149 22 0 0 0 8.61E+06 6.86E+06 - - - 9.3418 1 221125_WJC_METTL3_EV_vs_WT_F08.17407.17407.4 1.74E-10 22/102 K.R[166.11]GAPPSSNIEDFHGLLPK[136.11].G "sp|P43243|MATR3_HUMAN,tr|A8MXP9|A8MXP9_HUMAN,tr|D6R991|D6R991_HUMAN,tr|A0A0R4J2E8|A0A0R4J2E8_HUMAN,tr|H0Y8T4|H0Y8T4_HUMAN,tr|D6REM6|D6REM6_HUMAN" 6 1952.0235 1.47 120119 17407 4 1952.021502 489.0131 Matrin-3 OS=Homo sapiens OX=9606 GN=MATR3 PE=1 SV=2 6.75 2967 - 959678 - - - -1.0133 - 3.671 0.575 - 234.6 1 2 0 -0.002 18 0 0 0 1.21E+08 8.21E+07 - - - 4.6757 0.9999 221125_WJC_METTL3_EV_vs_WT_F08.17411.17411.4 2.00E-05 19/102 K.KQGGLGPMNIPLVSDPKR.T "sp|Q06830|PRDX1_HUMAN,tr|A0A0A0MSI0|A0A0A0MSI0_HUMAN" 2 1906.0459 0.66 120121 17411 4 1906.045213 477.5187 Peroxiredoxin-1 OS=Homo sapiens OX=9606 GN=PRDX1 PE=1 SV=1 9.99 2967.6 - 1.52E+06 - - - -0.3352 - 2.983 0.463 - 310.3 1 2 0 -0.0006 18 0 0 0 3.77E+07 5.73E+07 - - - 3.6302 1 221125_WJC_METTL3_EV_vs_WT_F08.17413.17413.3 1.96E-13 31/68 K.RPLDDGVGNQLGALVHQR.T sp|Q96I24|FUBP3_HUMAN 1 1944.029 1.91 120123 17413 3 1944.027686 649.0169 Far upstream element-binding protein 3 OS=Homo sapiens OX=9606 GN=FUBP3 PE=1 SV=2 6.75 2967.7 - 7.17E+06 - - - -0.6533 - 5.627 0.613 - 1303.2 1 2 0 -0.0013 18 0 0 0 2.09E+08 1.09E+08 - - - 9.6758 0.9999 221125_WJC_METTL3_EV_vs_WT_F08.17419.17419.4 0.000346 11/144 K.EKPELSEPSHLNGPSSDPEAAFLSR.D "sp|Q9H4A3|WNK1_HUMAN,tr|F5GWT4|F5GWT4_HUMAN,tr|A0A6Q8PFM0|A0A6Q8PFM0_HUMAN" 3 2693.2933 8.26 120127 17419 4 2693.289027 674.3306 Serine\threonine-protein kinase WNK1 OS=Homo sapiens OX=9606 GN=WNK1 PE=1 SV=2 4.57 2968.6 - 1.01E+06 - - - -1.5824 - 2.256 0.454 - 59.9 1 2 0 -0.0043 25 0 0 0 2.72E+07 3.30E+06 - - - 3.4353 1 221125_WJC_METTL3_EV_vs_WT_F08.17421.17421.3 6.16E-11 23/84 R.SSHLEVSQASQLLQQQQQQQLR.R "sp|O75376|NCOR1_HUMAN,tr|J3KT44|J3KT44_HUMAN,tr|E7EVU5|E7EVU5_HUMAN,tr|C9JAP0|C9JAP0_HUMAN,tr|J3KS51|J3KS51_HUMAN,tr|E7EW50|E7EW50_HUMAN" 6 2563.3103 1.25 120129 17421 3 2563.30765 855.444 Nuclear receptor corepressor 1 OS=Homo sapiens OX=9606 GN=NCOR1 PE=1 SV=2 6.47 2968.8 - 373493 - - - -1.0245 - 4.626 0.71 - 915.9 1 2 0 -0.0026 22 0 0 0 8.61E+06 6.86E+06 - - - 10.0865 1 221125_WJC_METTL3_EV_vs_WT_F08.17427.17427.4 1.58E-06 21/96 R.HDGSEPC[160.03]VDVLFGDGHR.L sp|Q96EL3|RM53_HUMAN 1 1895.8221 1.35 120133 17427 4 1895.82165 474.9628 "39S ribosomal protein L53, mitochondrial OS=Homo sapiens OX=9606 GN=MRPL53 PE=1 SV=1" 4.64 2969.6 - 1.11E+06 - - - -0.2163 - 3.231 0.583 - 353.8 1 2 0 -0.0004 17 0 0 0 9.13E+07 6.78E+07 - - - 4.7075 1 221125_WJC_METTL3_EV_vs_WT_F08.17428.17428.4 3.43E-11 21/132 R.EKEPIVGSTDYGKDEDSAEALLK.K "sp|Q13813|SPTN1_HUMAN,tr|A0A0D9SF54|A0A0D9SF54_HUMAN,tr|A0A0D9SGF6|A0A0D9SGF6_HUMAN" 3 2493.2122 1.41 120134 17428 4 2493.21391 624.3103 "Spectrin alpha chain, non-erythrocytic 1 OS=Homo sapiens OX=9606 GN=SPTAN1 PE=1 SV=3" 4.2 2969.7 - 850063 - - - 0.6682 - 3.862 0.627 - 351 1 2 2 0.0017 23 0 0 0 4.67E+07 3.32E+07 - - - 5.1207 1 221125_WJC_METTL3_EV_vs_WT_F08.17429.17429.3 7.95E-07 23/112 K.QK[136.11]GDTPASATAGDTLSVPAPAVQPEESLK[136.11].T "tr|A0A087WYS0|A0A087WYS0_HUMAN,tr|C9J406|C9J406_HUMAN,tr|H7C463|H7C463_HUMAN" 3 2880.4687 1.59 120135 17429 3 2880.466672 961.1635 MICOS complex subunit MIC60 OS=Homo sapiens OX=9606 GN=IMMT PE=1 SV=1 4.32 2969.9 - 1.11E+06 - - - -0.7204 - 3.732 0.6 - 271 1 2 1 -0.0021 29 0 0 0 8.35E+07 5.24E+07 - - - 8.2586 0.972 221125_WJC_METTL3_EV_vs_WT_F08.17430.17430.4 0.0551 19/126 R.IGFSVQPDRLELGKPDNNDGSK.L "sp|O95071|UBR5_HUMAN,tr|E7EMW7|E7EMW7_HUMAN" 2 2385.1925 0.69 120136 17430 4 2385.194128 597.3054 E3 ubiquitin-protein ligase UBR5 OS=Homo sapiens OX=9606 GN=UBR5 PE=1 SV=2 4.68 2970 - 733965 - - - 0.7027 - 1.933 0.212 - 101.3 1 2 1 0.0017 22 0 0 0 1.04E+07 1.52E+07 - - - 1.2864 1 221125_WJC_METTL3_EV_vs_WT_F08.17431.17431.4 5.34E-10 24/132 K.HSLPSGLGLSETQITSHGFDNTK[136.11].E sp|P53367|ARFP1_HUMAN 1 2433.2016 3.48 120137 17431 4 2433.205254 609.3077 Arfaptin-1 OS=Homo sapiens OX=9606 GN=ARFIP1 PE=1 SV=2 5.99 2970.1 - 631336 - - - 1.5153 - 3.893 0.572 - 447.6 1 2 0 0.0037 23 0 0 0 2.41E+07 6.94E+06 - - - 4.644 1 221125_WJC_METTL3_EV_vs_WT_F08.17433.17433.4 1.11E-09 20/114 K.HGVNVQSIADIHPIQVQPGR[166.11].L sp|P46019|KPB2_HUMAN 1 2174.1584 1.23 120139 17433 4 2174.162909 544.5469 "Phosphorylase b kinase regulatory subunit alpha, liver isoform OS=Homo sapiens OX=9606 GN=PHKA2 PE=1 SV=1" 6.92 2970.4 - 354076 - - - 2.0721 - 3.408 0.589 - 258 1 2 0 0.0045 20 0 0 0 6.44E+06 5.23E+06 - - - 4.7613 0.9913 221125_WJC_METTL3_EV_vs_WT_F08.17434.17434.4 0.0112 10/108 K.K[136.11]R[166.11]EPLNFGIPDGSTGFSSR[166.11].L "sp|O00559|RCAS1_HUMAN,tr|E9PND3|E9PND3_HUMAN,tr|E9PN10|E9PN10_HUMAN,tr|E9PJ40|E9PJ40_HUMAN" 4 2092.0696 0.54 120140 17434 4 2092.077212 524.0247 Receptor-binding cancer antigen expressed on SiSo cells OS=Homo sapiens OX=9606 GN=EBAG9 PE=1 SV=1 8.75 2970.5 - 333812 - - - 3.6423 - 2.106 0.338 - 68.8 1 2 1 0.0076 19 0 0 0 3.02E+06 5.64E+06 - - - 2.4178 1 221125_WJC_METTL3_EV_vs_WT_F08.17438.17438.4 7.65E-07 19/102 K.RGAPPSSNIEDFHGLLPK.G "sp|P43243|MATR3_HUMAN,tr|A8MXP9|A8MXP9_HUMAN,tr|D6R991|D6R991_HUMAN,tr|A0A0R4J2E8|A0A0R4J2E8_HUMAN,tr|H0Y8T4|H0Y8T4_HUMAN,tr|D6REM6|D6REM6_HUMAN" 6 1934.001 1.46 120142 17438 4 1934.002319 484.5075 Matrin-3 OS=Homo sapiens OX=9606 GN=MATR3 PE=1 SV=2 6.75 2971 - 1.43E+06 - - - 0.6768 - 2.423 0.486 - 177.3 1 2 0 0.0013 18 0 0 0 1.21E+08 8.27E+07 - - - 3.7589 1 221125_WJC_METTL3_EV_vs_WT_F08.17440.17440.4 7.64E-05 18/108 R.HALDAHQQSIPAVLEIPSK.E sp|Q16864|VATF_HUMAN 1 2053.0956 2.84 120144 17440 4 2053.093525 514.2812 V-type proton ATPase subunit F OS=Homo sapiens OX=9606 GN=ATP6V1F PE=1 SV=2 5.99 2971.3 - 523947 - - - -1.0297 - 3.035 0.547 - 231.3 1 2 0 -0.0021 19 0 0 0 1.08E+07 3.81E+06 - - - 4.3621 1 221125_WJC_METTL3_EV_vs_WT_F08.17448.17448.3 1.12E-11 20/88 K.HSLPSGLGLSETQITSHGFDNTK[136.11].E sp|P53367|ARFP1_HUMAN 1 2433.2016 1.61 120150 17448 3 2433.202073 812.0745 Arfaptin-1 OS=Homo sapiens OX=9606 GN=ARFIP1 PE=1 SV=2 5.99 2972.3 - 392479 - - - 0.208 - 3.825 0.654 - 329.7 1 2 0 0.0005 23 0 0 0 9.52E+06 5.93E+06 - - - 8.9785 0.9994 221125_WJC_METTL3_EV_vs_WT_F08.17449.17449.4 0.00588 13/144 K.FAC[160.03]NGTVIEHPEYGEVIQLQGDQRK.N "sp|P41567|EIF1_HUMAN,sp|O60739|EIF1B_HUMAN,tr|K7EM18|K7EM18_HUMAN,tr|K7EQP2|K7EQP2_HUMAN" 4 2887.3923 1.23 120151 17449 4 2887.38801 722.8553 Eukaryotic translation initiation factor 1 OS=Homo sapiens OX=9606 GN=EIF1 PE=1 SV=1 4.83 2972.4 - 379663 - - - -1.483 - 1.962 0.329 - 48.7 1 2 0 -0.0043 25 0 0 0 1.02E+07 8.33E+06 - - - 2.3028 0.9999 221125_WJC_METTL3_EV_vs_WT_F08.17456.17456.4 4.81E-11 22/120 K.QEILENK[136.11]DVVVQHVHFDGLGR[166.11].T sp|Q9Y512|SAM50_HUMAN 1 2449.2833 1.09 120155 17456 4 2449.281207 613.3281 Sorting and assembly machinery component 50 homolog OS=Homo sapiens OX=9606 GN=SAMM50 PE=1 SV=3 5.31 2973.3 - 1.10E+06 - - - -0.8451 - 3.746 0.566 - 319.5 1 2 1 -0.0021 21 0 0 0 2.29E+07 2.11E+07 - - - 4.5886 1 221125_WJC_METTL3_EV_vs_WT_F08.17457.17457.4 4.14E-06 17/114 K.HGVNVQSIADIHPIQVQPGR.L sp|P46019|KPB2_HUMAN 1 2164.1501 1.22 120156 17457 4 2164.150239 542.0448 "Phosphorylase b kinase regulatory subunit alpha, liver isoform OS=Homo sapiens OX=9606 GN=PHKA2 PE=1 SV=1" 6.92 2973.5 - 346866 - - - 0.0485 - 2.849 0.531 - 180.8 1 2 0 0.0001 20 0 0 0 6.44E+06 5.26E+06 - - - 4.1978 0.9978 221125_WJC_METTL3_EV_vs_WT_F08.17462.17462.4 0.00136 16/108 R.HALDAHQQSIPAVLEIPSK[136.11].E sp|Q16864|VATF_HUMAN 1 2061.1098 2.82 120159 17462 4 2062.112096 516.2847 V-type proton ATPase subunit F OS=Homo sapiens OX=9606 GN=ATP6V1F PE=1 SV=2 5.99 2974.1 - 323368 - - - 486.2705 - 3.013 0.447 - 155.2 1 2 0 1.0023 19 0 0 0 1.02E+07 3.61E+06 - - - 3.2122 1 221125_WJC_METTL3_EV_vs_WT_F08.17470.17470.3 7.02E-07 18/96 R.QSQIQVFEDGADTTSPETPDSSASK.V "sp|Q14203|DCTN1_HUMAN,tr|A0A804CDA6|A0A804CDA6_HUMAN,tr|E7EX90|E7EX90_HUMAN,tr|C9JJD0|C9JJD0_HUMAN,tr|A0A7P0Z4C3|A0A7P0Z4C3_HUMAN,tr|Q6AWB1|Q6AWB1_HUMAN,tr|E9PCY0|E9PCY0_HUMAN,tr|C9JKG6|C9JKG6_HUMAN" 8 2624.1726 2.34 120165 17470 3 2624.173863 875.7315 Dynactin subunit 1 OS=Homo sapiens OX=9606 GN=DCTN1 PE=1 SV=3 3.77 2975.2 - 505660 - - - 0.4946 - 3.192 0.637 - 255.1 1 2 0 0.0013 25 0 0 0 5.62E+07 2.40E+07 - - - 8.3118 1 221125_WJC_METTL3_EV_vs_WT_F08.17471.17471.3 9.30E-15 29/68 K.RGAPPSSNIEDFHGLLPK.G "sp|P43243|MATR3_HUMAN,tr|A8MXP9|A8MXP9_HUMAN,tr|D6R991|D6R991_HUMAN,tr|A0A0R4J2E8|A0A0R4J2E8_HUMAN,tr|H0Y8T4|H0Y8T4_HUMAN,tr|D6REM6|D6REM6_HUMAN" 6 1934.001 1.56 120166 17471 3 1934.003189 645.6743 Matrin-3 OS=Homo sapiens OX=9606 GN=MATR3 PE=1 SV=2 6.75 2975.3 - 1.44E+06 - - - 1.1267 - 4.642 0.671 - 1330.5 1 2 0 0.0022 18 0 0 0 7.46E+07 4.78E+07 - - - 9.8431 0.9999 221125_WJC_METTL3_EV_vs_WT_F08.17473.17473.4 0.000188 21/102 R.K[136.11]AGTQIENIDEDFR[166.11]DGLK[136.11].L "sp|O43707|ACTN4_HUMAN,tr|F5GXS2|F5GXS2_HUMAN,tr|K7EP19|K7EP19_HUMAN,tr|H7C144|H7C144_HUMAN" 4 2074.0541 1.07 120168 17473 4 2074.055862 519.5208 Alpha-actinin-4 OS=Homo sapiens OX=9606 GN=ACTN4 PE=1 SV=2 4.44 2975.5 - 559122 - - - 0.8409 - 3.647 0.525 - 289.7 1 2 1 0.0017 18 0 0 0 8.51E+06 7.93E+06 - - - 4.2384 0.9995 221125_WJC_METTL3_EV_vs_WT_F08.17474.17474.4 4.27E-07 21/102 R.KAGTQIENIDEDFRDGLK.L "sp|O43707|ACTN4_HUMAN,tr|F5GXS2|F5GXS2_HUMAN,tr|K7EP19|K7EP19_HUMAN,tr|H7C144|H7C144_HUMAN" 4 2048.0174 1.07 120169 17474 4 2048.024184 513.0116 Alpha-actinin-4 OS=Homo sapiens OX=9606 GN=ACTN4 PE=1 SV=2 4.44 2975.6 - 485604 - - - 3.289 - 3.666 0.498 - 502.9 1 2 1 0.0067 18 0 0 0 8.51E+06 7.93E+06 - - - 4.0037 0.9936 221125_WJC_METTL3_EV_vs_WT_F08.17477.17477.4 0.021 11/108 K.KYVATLGVEVHPLVFHTNR.G "sp|P62826|RAN_HUMAN,tr|H0YFC6|H0YFC6_HUMAN,tr|B5MDF5|B5MDF5_HUMAN,tr|J3KQE5|J3KQE5_HUMAN,tr|F5H018|F5H018_HUMAN" 5 2179.1902 0.83 120172 17477 4 2179.195596 545.8048 GTP-binding nuclear protein Ran OS=Homo sapiens OX=9606 GN=RAN PE=1 SV=3 8.6 2976 - 293208 - - - 2.4725 - 2.669 0.236 - 82.6 1 2 0 0.0054 19 0 0 0 6.38E+06 7.65E+06 - - - 1.6107 0.8304 221125_WJC_METTL3_EV_vs_WT_F08.17480.17480.4 0.0248 9/108 K.ESQEGPK[136.11]HPTGPFFPVLSK[136.11].D sp|Q9UKJ3|GPTC8_HUMAN 1 2097.0866 0.96 120175 17480 4 2097.089023 525.2789 G patch domain-containing protein 8 OS=Homo sapiens OX=9606 GN=GPATCH8 PE=1 SV=2 6.85 2976.4 - 143258 - - - 1.1597 - 1.766 0.139 - 60.9 1 2 1 0.0024 19 0 0 0 6.50E+06 6.75E+06 - - - 0.6276 0.9995 221125_WJC_METTL3_EV_vs_WT_F08.17486.17486.4 0.000609 13/108 R.SDKGNEFVVIHNGIITNYK.D sp|O94808|GFPT2_HUMAN 1 2147.1011 0.69 120179 17486 4 2147.102347 537.7826 Glutamine--fructose-6-phosphate aminotransferase [isomerizing] 2 OS=Homo sapiens OX=9606 GN=GFPT2 PE=1 SV=3 6.47 2977.2 - 353260 - - - 0.5724 - 2.627 0.402 - 129.6 1 2 1 0.0012 19 0 0 0 1.92E+06 2.79E+06 - - - 3.0514 1 221125_WJC_METTL3_EV_vs_WT_F08.17487.17487.4 4.51E-08 14/108 K.K[136.11]YVATLGVEVHPLVFHTNR[166.11].G "sp|P62826|RAN_HUMAN,tr|H0YFC6|H0YFC6_HUMAN,tr|B5MDF5|B5MDF5_HUMAN,tr|J3KQE5|J3KQE5_HUMAN,tr|F5H018|F5H018_HUMAN" 5 2197.2127 0.83 120180 17487 4 2197.215997 550.3104 GTP-binding nuclear protein Ran OS=Homo sapiens OX=9606 GN=RAN PE=1 SV=3 8.6 2977.4 - 323056 - - - 1.5106 - 2.895 0.546 - 88.6 1 2 0 0.0033 19 0 0 0 6.38E+06 7.65E+06 - - - 4.3371 1 221125_WJC_METTL3_EV_vs_WT_F08.17493.17493.3 1.42E-09 19/96 R.QSQIQVFEDGADTTSPETPDSSASK[136.11].V "sp|Q14203|DCTN1_HUMAN,tr|A0A804CDA6|A0A804CDA6_HUMAN,tr|E7EX90|E7EX90_HUMAN,tr|C9JJD0|C9JJD0_HUMAN,tr|A0A7P0Z4C3|A0A7P0Z4C3_HUMAN,tr|Q6AWB1|Q6AWB1_HUMAN,tr|E9PCY0|E9PCY0_HUMAN,tr|C9JKG6|C9JKG6_HUMAN" 8 2632.1868 2.34 120184 17493 3 2632.186932 878.4029 Dynactin subunit 1 OS=Homo sapiens OX=9606 GN=DCTN1 PE=1 SV=3 3.77 2978.1 - 775506 - - - 0.0634 - 3.244 0.62 - 293.2 1 2 0 0.0002 25 0 0 0 5.62E+07 2.40E+07 - - - 8.1597 0.9999 221125_WJC_METTL3_EV_vs_WT_F08.17494.17494.4 3.59E-09 25/168 K.SQWVAPSSVVLHDEGQNEEDVEKEEETER.M "sp|Q9Y2L1|RRP44_HUMAN,tr|F2Z2C0|F2Z2C0_HUMAN,tr|G3V1J5|G3V1J5_HUMAN" 3 3354.5124 6.85 120185 17494 4 3354.514204 839.6354 Exosome complex exonuclease RRP44 OS=Homo sapiens OX=9606 GN=DIS3 PE=1 SV=2 4.04 2978.3 - 766106 - - - 0.5372 - 3.506 0.581 - 313.8 1 2 1 0.0018 29 0 0 0 6.47E+06 9.45E+05 - - - 4.6691 0.9998 221125_WJC_METTL3_EV_vs_WT_F08.17496.17496.4 8.61E-06 17/174 R.VVVPATEEEAEVDEFPTDGEMSAQEEDRRK.E "sp|O00541|PESC_HUMAN,tr|B3KXD6|B3KXD6_HUMAN,tr|B5MCF9|B5MCF9_HUMAN" 3 3391.5362 1.15 120187 17496 4 3391.537711 848.8913 Pescadillo homolog OS=Homo sapiens OX=9606 GN=PES1 PE=1 SV=1 3.96 2978.5 - 586349 - - - 0.4532 - 3.236 0.487 - 107.9 1 2 1 0.0015 30 0 0 0 6.11E+06 5.31E+06 - - - 3.8238 1 221125_WJC_METTL3_EV_vs_WT_F08.17500.17500.3 7.37E-10 13/116 F.STPASQLFSPHGSNPSTPAATPVPTASPVK.A sp|Q86XN7|PRSR1_HUMAN 1 2930.4774 3.64 120191 17500 3 2930.474133 977.8331 Proline and serine-rich protein 1 OS=Homo sapiens OX=9606 GN=PROSER1 PE=1 SV=2 8.49 2979 - 270333 - - - -1.1152 - 2.959 0.673 - 114.2 1 1 0 -0.0033 30 0 0 0 6.60E+06 1.81E+06 - - - 8.5382 1 221125_WJC_METTL3_EV_vs_WT_F08.17504.17504.3 1.73E-07 15/68 K.KQELIEDLQPDINQNVQK.L sp|Q9UJC3|HOOK1_HUMAN 1 2151.1172 2.11 120193 17504 3 2151.121249 718.0463 Protein Hook homolog 1 OS=Homo sapiens OX=9606 GN=HOOK1 PE=1 SV=2 4.32 2979.6 - 584556 - - - 1.8999 - 3.414 0.541 - 249 1 2 0 0.0041 18 0 0 0 1.13E+07 5.35E+06 - - - 7.628 0.977 221125_WJC_METTL3_EV_vs_WT_F08.17507.17507.4 0.0425 10/114 K.NIK[136.11]PLLSTFSQVPGSENEK[136.11]K[136.11].C "sp|Q96FV9|THOC1_HUMAN,tr|J3QQZ3|J3QQZ3_HUMAN,tr|J3KRD7|J3KRD7_HUMAN,tr|A0A087WWS1|A0A087WWS1_HUMAN,tr|A0A087WY84|A0A087WY84_HUMAN,tr|J3KT14|J3KT14_HUMAN" 6 2239.2274 0.9 120196 17507 4 2239.235023 560.8141 THO complex subunit 1 OS=Homo sapiens OX=9606 GN=THOC1 PE=1 SV=1 8.5 2979.9 - 278737 - - - 3.3829 - 1.804 0.224 - 46.8 1 2 0 0.0076 20 0 0 0 4.83E+06 5.37E+06 - - - 1.3708 1 221125_WJC_METTL3_EV_vs_WT_F08.17508.17508.4 2.09E-06 14/78 K.HWPFMVVNDAGR[166.11]PK[136.11].V "sp|P11142|HSP7C_HUMAN,tr|E9PQQ4|E9PQQ4_HUMAN,tr|E9PNE6|E9PNE6_HUMAN,tr|E9PKE3|E9PKE3_HUMAN,tr|E9PN89|E9PN89_HUMAN,tr|E9PLF4|E9PLF4_HUMAN,tr|E9PK54|E9PK54_HUMAN,tr|E9PN25|E9PN25_HUMAN,tr|E9PPY6|E9PPY6_HUMAN,tr|E9PQK7|E9PQK7_HUMAN" 10 1670.847 0.2 120197 17508 4 1670.850936 418.719 Heat shock cognate 71 kDa protein OS=Homo sapiens OX=9606 GN=HSPA8 PE=1 SV=1 8.75 2980.1 - 215446 - - - 2.3341 - 2.926 0.539 - 199.4 1 2 0 0.0039 14 0 0 0 5.66E+06 2.80E+07 - - - 4.3071 1 221125_WJC_METTL3_EV_vs_WT_F08.17512.17512.3 3.15E-12 22/100 R.LQQLLPASQSTQLPC[160.03]SSSPQETTQSR.P "sp|Q6W2J9|BCOR_HUMAN,tr|H7BZ37|H7BZ37_HUMAN,tr|H7C2V9|H7C2V9_HUMAN,tr|H7C231|H7C231_HUMAN" 4 2871.4032 2.14 120199 17512 3 2871.406066 958.1417 BCL-6 corepressor OS=Homo sapiens OX=9606 GN=BCOR PE=1 SV=1 5.99 2980.5 - 626201 - - - 0.9807 - 3.764 0.677 - 372.8 1 1 0 0.0028 26 0 0 0 1.67E+07 7.82E+06 - - - 9.1366 0.9986 221125_WJC_METTL3_EV_vs_WT_F08.17514.17514.3 4.50E-10 16/96 F.SSASGGFGSTATSNTSNLFGNSGAK.T "sp|P35658|NU214_HUMAN,tr|A0A494C0Y1|A0A494C0Y1_HUMAN,tr|A0A0A0MSW3|A0A0A0MSW3_HUMAN,tr|B7ZAV2|B7ZAV2_HUMAN,tr|A0A494C1F2|A0A494C1F2_HUMAN,tr|H0Y837|H0Y837_HUMAN" 6 2306.0411 1.71 120201 17514 3 2306.043695 769.6876 Nuclear pore complex protein Nup214 OS=Homo sapiens OX=9606 GN=NUP214 PE=1 SV=2 8.47 2980.8 - 639285 - - - 1.1266 - 2.877 0.638 - 212.6 1 1 0 0.0026 25 0 0 0 2.08E+07 1.22E+07 - - - 8.0835 0.9976 221125_WJC_METTL3_EV_vs_WT_F08.17516.17516.3 0.0194 15/68 K.K[136.11]QELIEDLQPDINQNVQK[136.11].L sp|Q9UJC3|HOOK1_HUMAN 1 2167.1456 2.2 120203 17516 3 2168.146691 723.3891 Protein Hook homolog 1 OS=Homo sapiens OX=9606 GN=HOOK1 PE=1 SV=2 4.32 2981 - 344953 - - - 461.9574 - 3.122 0.384 - 283.5 1 2 0 1.0011 18 0 0 0 1.13E+07 5.13E+06 - - - 5.3788 0.9981 221125_WJC_METTL3_EV_vs_WT_F08.17523.17523.3 7.51E-10 15/96 F.SSASGGFGSTATSNTSNLFGNSGAK[136.11].T "sp|P35658|NU214_HUMAN,tr|A0A494C0Y1|A0A494C0Y1_HUMAN,tr|A0A0A0MSW3|A0A0A0MSW3_HUMAN,tr|B7ZAV2|B7ZAV2_HUMAN,tr|A0A494C1F2|A0A494C1F2_HUMAN,tr|H0Y837|H0Y837_HUMAN" 6 2314.0553 1.72 120208 17523 3 2314.058273 772.359 Nuclear pore complex protein Nup214 OS=Homo sapiens OX=9606 GN=NUP214 PE=1 SV=2 8.47 2981.9 - 459935 - - - 1.2861 - 2.989 0.587 - 162.4 1 1 0 0.003 25 0 0 0 2.13E+07 1.24E+07 - - - 7.6027 0.9994 221125_WJC_METTL3_EV_vs_WT_F08.17524.17524.4 0.134 Nov-84 R.STSHK[136.11]PDEIYGMIER[166.11].L sp|Q86U44|MTA70_HUMAN 1 1779.8581 0 120209 17524 4 1779.858836 445.9718 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 5.42 2982 - 385499 - - - 0.4394 - 2.005 0.326 - 55.2 1 2 0 0.0008 15 0 0 0 5.48E+04 1.46E+07 - - - 2.3122 0.9997 221125_WJC_METTL3_EV_vs_WT_F08.17529.17529.4 5.16E-05 13/114 K.NIKPLLSTFSQVPGSENEKK.C "sp|Q96FV9|THOC1_HUMAN,tr|J3QQZ3|J3QQZ3_HUMAN,tr|J3KRD7|J3KRD7_HUMAN,tr|A0A087WWS1|A0A087WWS1_HUMAN,tr|A0A087WY84|A0A087WY84_HUMAN,tr|J3KT14|J3KT14_HUMAN" 6 2215.1848 0.9 120212 17529 4 2215.189877 554.8035 THO complex subunit 1 OS=Homo sapiens OX=9606 GN=THOC1 PE=1 SV=1 8.5 2982.7 - 303491 - - - 2.2702 - 2.272 0.39 - 87 1 2 0 0.005 20 0 0 0 4.83E+06 5.37E+06 - - - 2.8935 1 221125_WJC_METTL3_EV_vs_WT_F08.17533.17533.4 1.84E-09 31/168 K.IQIASESSGIPERPC[160.03]VLTGTPESIEQAKR.L sp|Q96I24|FUBP3_HUMAN 1 3152.6136 1.81 120215 17533 4 3152.620032 789.1607 Far upstream element-binding protein 3 OS=Homo sapiens OX=9606 GN=FUBP3 PE=1 SV=2 4.95 2983.2 - 2.33E+06 - - - 2.0475 - 4.69 0.587 - 386.3 1 2 0 0.0065 29 0 0 0 1.19E+09 6.60E+08 - - - 4.8097 1 221125_WJC_METTL3_EV_vs_WT_F08.17535.17535.3 6.96E-11 24/100 R.LQQLLPASQSTQLPC[160.03]SSSPQETTQSR[166.11].P "sp|Q6W2J9|BCOR_HUMAN,tr|H7BZ37|H7BZ37_HUMAN,tr|H7C2V9|H7C2V9_HUMAN,tr|H7C231|H7C231_HUMAN" 4 2881.4115 2.14 120216 17535 3 2881.410289 961.4778 BCL-6 corepressor OS=Homo sapiens OX=9606 GN=BCOR PE=1 SV=1 5.99 2983.5 - 566352 - - - -0.4272 - 4.039 0.661 - 516.1 1 1 0 -0.0012 26 0 0 0 1.67E+07 7.82E+06 - - - 9.1208 0.8324 221125_WJC_METTL3_EV_vs_WT_F08.17536.17536.4 0.0115 16/138 E.VSNRFSGVPDRFSGSGSGTDFTLK.L "sp|A0A075B6S2|KVD29_HUMAN,sp|A0A0A0MRZ7|KVD26_HUMAN" 2 2517.2248 1.77 120217 17536 4 2517.231377 630.3135 Immunoglobulin kappa variable 2D-29 OS=Homo sapiens OX=9606 GN=IGKV2D-29 PE=3 SV=1 8.72 2983.6 - 458303 - - - 2.6068 - 2.417 0.386 - 110.4 1 1 2 0.0066 24 0 0 0 1.57E+07 8.90E+06 - - - 2.8672 0.9998 221125_WJC_METTL3_EV_vs_WT_F08.17542.17542.3 4.65E-07 Dec-60 K.EESSSISSLK[136.11]DEFTQR[166.11].L "sp|P82094|TMF1_HUMAN,tr|F8WF45|F8WF45_HUMAN,tr|A0A2R8Y7M0|A0A2R8Y7M0_HUMAN" 3 1859.8868 1.66 120221 17542 3 1859.891054 620.9695 TATA element modulatory factor OS=Homo sapiens OX=9606 GN=TMF1 PE=1 SV=2 4.41 2984.4 - 203822 - - - 2.3028 - 2.841 0.549 - 211.2 1 2 1 0.0043 16 0 0 0 6.54E+06 3.93E+06 - - - 7.3388 0.9997 221125_WJC_METTL3_EV_vs_WT_F08.17544.17544.4 3.69E-09 20/144 R.SSAAAAAAAAAGQIHHVTQNGGLYK.R sp|O15270|SPTC2_HUMAN 1 2364.1935 0.43 120223 17544 4 2364.202539 592.0556 Serine palmitoyltransferase 2 OS=Homo sapiens OX=9606 GN=SPTLC2 PE=1 SV=1 8.36 2984.7 - 515378 - - - 3.8423 - 3.859 0.463 - 208.3 1 2 0 0.0091 25 0 0 0 1.10E+07 2.58E+07 - - - 3.683 1 221125_WJC_METTL3_EV_vs_WT_F08.17545.17545.2 3.18E-10 14/48 F.SSASGGFGSTATSNTSNLFGNSGAK.T "sp|P35658|NU214_HUMAN,tr|A0A494C0Y1|A0A494C0Y1_HUMAN,tr|A0A0A0MSW3|A0A0A0MSW3_HUMAN,tr|B7ZAV2|B7ZAV2_HUMAN,tr|A0A494C1F2|A0A494C1F2_HUMAN,tr|H0Y837|H0Y837_HUMAN" 6 2306.0411 3.49 120224 17545 2 2306.044336 1154.0278 Nuclear pore complex protein Nup214 OS=Homo sapiens OX=9606 GN=NUP214 PE=1 SV=2 8.47 2984.8 - 123945 - - - 1.4046 - 3.106 0.71 - 349.3 1 1 0 0.0032 25 0 0 0 2.64E+06 7.58E+05 - - - 7.0704 0.9999 221125_WJC_METTL3_EV_vs_WT_F08.17550.17550.4 1.48E-05 17/168 K.IQIASESSGIPER[166.11]PC[160.03]VLTGTPESIEQAK[136.11]R[166.11].L sp|Q96I24|FUBP3_HUMAN 1 3180.6443 1.96 120227 17550 4 3180.649392 796.1684 Far upstream element-binding protein 3 OS=Homo sapiens OX=9606 GN=FUBP3 PE=1 SV=2 4.95 2985.5 - 784435 - - - 1.5956 - 3.066 0.452 - 79.4 1 2 0 0.0051 29 0 0 0 1.66E+08 8.47E+07 - - - 3.5041 0.9998 221125_WJC_METTL3_EV_vs_WT_F08.17553.17553.3 1.17E-05 Sep-52 K.K[136.11]GPGEVAGTVTGQK[136.11].R "sp|Q86U44|MTA70_HUMAN,tr|F5H6D8|F5H6D8_HUMAN,tr|H0YFV6|H0YFV6_HUMAN,tr|B4DTN4|B4DTN4_HUMAN" 4 1343.738 0.001 120230 17553 3 1343.740948 448.9199 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 8.59 2985.9 - 159522 - - - 2.2095 - 1.977 0.439 - 124.8 1 2 0 0.003 14 0 0 0 0.00E+00 1.43E+07 - - - 5.2449 1 221125_WJC_METTL3_EV_vs_WT_F08.17559.17559.4 5.37E-11 21/162 K.GHSTC[160.03]LSEGALSPDGTVLATASHDGYVK[136.11].F sp|Q6P2E9|EDC4_HUMAN 1 2837.3381 1.93 120234 17559 4 2837.346225 710.3418 Enhancer of mRNA-decapping protein 4 OS=Homo sapiens OX=9606 GN=EDC4 PE=1 SV=1 5.21 2986.7 - 288464 - - - 2.8506 - 4.08 0.653 - 319 1 2 0 0.0081 28 0 0 0 3.34E+07 1.73E+07 - - - 5.344 0.9999 221125_WJC_METTL3_EV_vs_WT_F08.17565.17565.3 0.000175 13/68 R.VAPEEHPVLLTEAPLNPK[136.11].A "sp|P63261|ACTG_HUMAN,sp|P60709|ACTB_HUMAN,tr|A0A804GS07|A0A804GS07_HUMAN,tr|I3L3I0|I3L3I0_HUMAN,tr|G5E9R0|G5E9R0_HUMAN,tr|E7EVS6|E7EVS6_HUMAN,tr|A0A6Q8PFE4|A0A6Q8PFE4_HUMAN,tr|J3KT65|J3KT65_HUMAN,tr|I3L3R2|I3L3R2_HUMAN,tr|K7EM38|K7EM38_HUMAN,tr|A0A6Q8PH58|A0A6Q8PH58_HUMAN,tr|I3L1U9|I3L1U9_HUMAN,tr|A0A2R8Y793|A0A2R8Y793_HUMAN,tr|I3L4N8|I3L4N8_HUMAN,tr|A0A2R8YGF8|A0A2R8YGF8_HUMAN" 15 1961.0713 0.97 120238 17565 3 1961.073594 654.6977 "Actin, cytoplasmic 2 OS=Homo sapiens OX=9606 GN=ACTG1 PE=1 SV=1" 4.75 2987.4 - 278209 - - - 1.1555 - 2.448 0.379 - 182.9 1 2 0 0.0023 18 0 0 0 1.13E+07 1.17E+07 - - - 4.9942 0.9204 221125_WJC_METTL3_EV_vs_WT_F08.17566.17566.2 1.04E-05 Jul-40 K.DHTPSQELALTQSVGGDSSAD.R "sp|Q86U44|MTA70_HUMAN,tr|H0YFV6|H0YFV6_HUMAN" 2 2113.94 - 120239 17566 2 2113.930571 1057.9773 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 4.04 2987.6 - 151287 - - - -4.4538 - 1.898 0.596 - 112 1 1 0 -0.0094 21 0 0 0 - - - - - 5.0155 0.9997 221125_WJC_METTL3_EV_vs_WT_F08.17574.17574.3 1.18E-08 15/84 K.VPEIEVTVEGPNNNNPQTSAVR[166.11].T "sp|P78347|GTF2I_HUMAN,tr|A0A494C1K3|A0A494C1K3_HUMAN" 2 2373.18 1.25 120244 17574 3 2373.189019 792.0673 General transcription factor II-I OS=Homo sapiens OX=9606 GN=GTF2I PE=1 SV=2 4.25 2988.7 - 334124 - - - 3.8059 - 3.476 0.424 - 200.1 1 2 0 0.009 22 0 0 0 5.66E+06 4.54E+06 - - - 6.2185 1 221125_WJC_METTL3_EV_vs_WT_F08.17576.17576.4 2.00E-06 19/132 K.SVEMHHEALSEALPGDNVGFNVK[136.11].N "sp|Q05639|EF1A2_HUMAN,sp|P68104|EF1A1_HUMAN,tr|A0A7I2V659|A0A7I2V659_HUMAN,tr|A0A7I2V3H3|A0A7I2V3H3_HUMAN,tr|A0A2U3TZH3|A0A2U3TZH3_HUMAN,tr|A0A7I2V5N4|A0A7I2V5N4_HUMAN,tr|A0A087WVQ9|A0A087WVQ9_HUMAN,tr|A0A087WV01|A0A087WV01_HUMAN" 8 2487.1944 0.37 120246 17576 4 2487.199344 622.8059 Elongation factor 1-alpha 2 OS=Homo sapiens OX=9606 GN=EEF1A2 PE=1 SV=1 4.8 2989 - 289262 - - - 1.9986 - 3.424 0.581 - 220.4 1 2 0 0.005 23 0 0 0 9.14E+06 2.46E+07 - - - 4.6804 0.9962 221125_WJC_METTL3_EV_vs_WT_F08.17580.17580.4 3.29E-10 27/168 R.AAASLAAVSGTAAASLGSAQPTDLGAHKR.P sp|Q7Z5L9|I2BP2_HUMAN 1 2649.3834 1.6 120248 17580 4 2649.381691 663.3531 Interferon regulatory factor 2-binding protein 2 OS=Homo sapiens OX=9606 GN=IRF2BP2 PE=1 SV=2 8.8 2989.5 - 1.13E+06 - - - -0.6605 - 4.721 0.493 - 280.8 1 1 0 -0.0018 29 0 0 0 3.84E+07 2.40E+07 - - - 3.9949 1 221125_WJC_METTL3_EV_vs_WT_F08.17582.17582.3 1.97E-10 16/88 R.SKADC[160.03]PTMEAQTTLTTNDIVISK.L sp|Q13123|RED_HUMAN 1 2523.2197 1.05 120250 17582 3 2523.215543 842.0805 Protein Red OS=Homo sapiens OX=9606 GN=IK PE=1 SV=3 4.56 2989.8 - 268563 - - - -1.6297 - 3.359 0.678 - 261.5 1 2 1 -0.0041 23 0 0 0 2.45E+07 2.34E+07 - - - 8.9403 1 221125_WJC_METTL3_EV_vs_WT_F08.17586.17586.4 2.11E-13 29/162 K.GHSTC[160.03]LSEGALSPDGTVLATASHDGYVK.F sp|Q6P2E9|EDC4_HUMAN 1 2829.3239 1.39 120252 17586 4 2829.325451 708.3383 Enhancer of mRNA-decapping protein 4 OS=Homo sapiens OX=9606 GN=EDC4 PE=1 SV=1 5.21 2990.3 - 821722 - - - 0.5351 - 5.613 0.674 - 569.4 1 2 0 0.0015 28 0 0 0 2.20E+07 1.58E+07 - - - 5.6277 1 221125_WJC_METTL3_EV_vs_WT_F08.17589.17589.3 4.68E-10 22/112 K.VVGDRENGSDNLPSSAGSGDKPLSDPAPF.- "sp|O43399|TPD54_HUMAN,tr|A0A087WZ51|A0A087WZ51_HUMAN" 2 2884.3475 1.74 120255 17589 3 2884.346294 962.4564 Tumor protein D54 OS=Homo sapiens OX=9606 GN=TPD52L2 PE=1 SV=2 4.04 2990.7 - 635825 - - - -0.4212 - 4.168 0.605 - 146 1 2 1 -0.0012 29 0 0 0 1.08E+08 6.22E+07 - - - 8.5688 0.9866 221125_WJC_METTL3_EV_vs_WT_F08.17590.17590.4 2.81E-07 14/156 E.QGEGSSGVSSLLLHPEPVPGPEK[136.11]ENVR[166.11].T "sp|A0A1B0GTU1|ZC11B_HUMAN,sp|O75152|ZC11A_HUMAN,tr|E9PBY7|E9PBY7_HUMAN,tr|A0A1W2PPR9|A0A1W2PPR9_HUMAN,tr|A0A494C0C4|A0A494C0C4_HUMAN,tr|E9PQ61|E9PQ61_HUMAN" 6 2816.4424 0.8 120256 17590 4 2816.445316 705.1179 Zinc finger CCCH domain-containing protein 11B OS=Homo sapiens OX=9606 GN=ZC3H11B PE=4 SV=1 4.91 2990.8 - 537456 - - - 1.051 - 3.25 0.516 - 78.8 1 1 1 0.003 27 0 0 0 5.44E+06 6.80E+06 - - - 4.0852 0.9964 221125_WJC_METTL3_EV_vs_WT_F08.17594.17594.4 3.14E-09 29/168 R.AAASLAAVSGTAAASLGSAQPTDLGAHK[136.11]R[166.11].P sp|Q7Z5L9|I2BP2_HUMAN 1 2667.4059 1.6 120258 17594 4 2667.401127 667.8588 Interferon regulatory factor 2-binding protein 2 OS=Homo sapiens OX=9606 GN=IRF2BP2 PE=1 SV=2 8.8 2991.3 - 1.44E+06 - - - -1.7935 - 4.985 0.52 - 348.9 1 1 0 -0.0048 29 0 0 0 3.84E+07 2.40E+07 - - - 4.2458 1 221125_WJC_METTL3_EV_vs_WT_F08.17598.17598.3 2.67E-08 14/80 K.TQTVC[160.03]NFTDGALVQHQEWDGK.E "sp|Q01469|FABP5_HUMAN,sp|A8MUU1|FB5L3_HUMAN,tr|I6L8B7|I6L8B7_HUMAN" 3 2433.1019 89.8 120262 17598 3 2433.106085 812.0413 Fatty acid-binding protein 5 OS=Homo sapiens OX=9606 GN=FABP5 PE=1 SV=3 4.53 2991.9 - 383905 - - - 1.7106 - 3.636 0.647 - 189 1 2 0 0.0042 21 0 0 0 8.43E+06 9.39E+04 - - - 8.8471 0.9987 221125_WJC_METTL3_EV_vs_WT_F08.17611.17611.3 0.0436 Sep-56 R.ETNLDSLPLVDTHSK[136.11].R sp|P08670|VIME_HUMAN 1 1675.8508 4.43 120269 17611 3 1675.853076 559.6242 Vimentin OS=Homo sapiens OX=9606 GN=VIM PE=1 SV=4 4.54 2993.5 - 1.11E+06 - - - 1.3402 - 1.981 0.267 - 98.5 1 2 0 0.0022 15 0 0 0 1.35E+08 3.04E+07 - - - 3.2999 1 221125_WJC_METTL3_EV_vs_WT_F08.17614.17614.3 8.94E-16 20/88 R.SK[136.11]ADC[160.03]PTMEAQTTLTTNDIVISK[136.11].L sp|Q13123|RED_HUMAN 1 2539.2481 1.05 120271 17614 3 2539.242257 847.4233 Protein Red OS=Homo sapiens OX=9606 GN=IK PE=1 SV=3 4.56 2993.8 - 785468 - - - -2.2834 - 4.211 0.707 - 472.1 1 2 1 -0.0058 23 0 0 0 2.45E+07 2.34E+07 - - - 9.7935 0.9985 221125_WJC_METTL3_EV_vs_WT_F08.17615.17615.3 7.22E-06 18/100 K.APSQALVQNIGQPTQGSPQPVGQQAN.N sp|Q9Y5A9|YTHD2_HUMAN 1 2614.3099 - 120272 17615 3 2614.306993 872.4439 YTH domain-containing family protein 2 OS=Homo sapiens OX=9606 GN=YTHDF2 PE=1 SV=2 5.57 2993.9 - 777617 - - - -1.128 - 3.546 0.564 - 293.8 1 1 0 -0.0029 26 0 0 0 - - - - - 7.7394 1 221125_WJC_METTL3_EV_vs_WT_F08.17620.17620.3 1.17E-11 20/112 K.VVGDR[166.11]ENGSDNLPSSAGSGDK[136.11]PLSDPAPF.- "sp|O43399|TPD54_HUMAN,tr|A0A087WZ51|A0A087WZ51_HUMAN" 2 2902.37 1.74 120275 17620 3 2902.381225 968.4639 Tumor protein D54 OS=Homo sapiens OX=9606 GN=TPD52L2 PE=1 SV=2 4.04 2994.5 - 1.36E+06 - - - 3.8748 - 4.139 0.655 - 129.9 1 2 1 0.0112 29 0 0 0 1.08E+08 6.22E+07 - - - 9.1074 1 221125_WJC_METTL3_EV_vs_WT_F08.17624.17624.4 1.49E-07 32/228 R.IFPPETSASVAATPPPSTASAPAAVNSSASADKPLSNMK.L "sp|P09874|PARP1_HUMAN,tr|A0A7I2V3E1|A0A7I2V3E1_HUMAN" 2 3766.8724 1.52 120279 17624 4 3766.873617 942.7254 Poly [ADP-ribose] polymerase 1 OS=Homo sapiens OX=9606 GN=PARP1 PE=1 SV=4 6.07 2995 - 483041 - - - 0.3308 - 4.392 0.547 - 338.6 1 2 0 0.0012 39 0 0 0 3.23E+07 2.13E+07 - - - 4.416 1 221125_WJC_METTL3_EV_vs_WT_F08.17631.17631.3 1.13E-08 14/52 K.HWPFMVVNDAGR[166.11]PK[136.11].V "sp|P11142|HSP7C_HUMAN,tr|E9PQQ4|E9PQQ4_HUMAN,tr|E9PNE6|E9PNE6_HUMAN,tr|E9PKE3|E9PKE3_HUMAN,tr|E9PN89|E9PN89_HUMAN,tr|E9PLF4|E9PLF4_HUMAN,tr|E9PK54|E9PK54_HUMAN,tr|E9PN25|E9PN25_HUMAN,tr|E9PPY6|E9PPY6_HUMAN,tr|E9PQK7|E9PQK7_HUMAN" 10 1670.847 0.1 120284 17631 3 1670.846907 557.9563 Heat shock cognate 71 kDa protein OS=Homo sapiens OX=9606 GN=HSPA8 PE=1 SV=1 8.75 2995.8 - 1.85E+06 - - - -0.0772 - 2.985 0.589 - 343.6 1 2 0 -0.0001 14 0 0 0 1.05E+07 1.01E+08 - - - 8.013 1 221125_WJC_METTL3_EV_vs_WT_F08.17641.17641.3 7.83E-08 18/96 K.TQEDPKPFC[160.03]VGSAPPSVDVTPTYTK.D "sp|Q6W2J9|BCOR_HUMAN,tr|H7BZ37|H7BZ37_HUMAN,tr|A1A564|A1A564_HUMAN,tr|H7C2V9|H7C2V9_HUMAN,tr|H7BYY2|H7BYY2_HUMAN,tr|H7C231|H7C231_HUMAN" 6 2720.3003 1.94 120288 17641 3 2720.296148 907.7741 BCL-6 corepressor OS=Homo sapiens OX=9606 GN=BCOR PE=1 SV=1 4.56 2997 - 1.11E+06 - - - -1.5439 - 3.241 0.53 - 153.2 1 2 0 -0.0042 25 0 0 0 1.32E+08 6.80E+07 - - - 7.1531 0.93 221125_WJC_METTL3_EV_vs_WT_F08.17643.17643.4 0.000134 Dec-96 Q.FEDVRDAEDALHNLDRK.W "sp|O75494|SRS10_HUMAN,tr|Q5JRI1|Q5JRI1_HUMAN" 2 2041.9817 1.91 120289 17643 4 2041.980799 511.5027 Serine\arginine-rich splicing factor 10 OS=Homo sapiens OX=9606 GN=SRSF10 PE=1 SV=1 4.52 2997.2 - 288569 - - - -0.4564 - 2.174 0.395 - 143.6 1 1 1 -0.0009 17 0 0 0 9.72E+06 5.09E+06 - - - 2.9334 1 221125_WJC_METTL3_EV_vs_WT_F08.17648.17648.3 1.04E-06 18/72 R.EGRPSGEAFVELESEDEVK.L "sp|P31943|HNRH1_HUMAN,tr|E7EQJ0|E7EQJ0_HUMAN,tr|D6RIH9|D6RIH9_HUMAN,tr|D6RJ04|D6RJ04_HUMAN,tr|D6RFM3|D6RFM3_HUMAN,tr|E9PCY7|E9PCY7_HUMAN,tr|D6RIT2|D6RIT2_HUMAN,tr|D6R9T0|D6R9T0_HUMAN,tr|D6RIU0|D6RIU0_HUMAN,tr|D6RAM1|D6RAM1_HUMAN,tr|D6RBM0|D6RBM0_HUMAN,tr|G8JLB6|G8JLB6_HUMAN,tr|D6RDL0|D6RDL0_HUMAN,tr|D6RDU3|D6RDU3_HUMAN,tr|E7EN40|E7EN40_HUMAN" 15 2105.9753 1.67 120293 17648 3 2105.972289 702.999 Heterogeneous nuclear ribonucleoprotein H OS=Homo sapiens OX=9606 GN=HNRNPH1 PE=1 SV=4 4.06 2997.8 - 590048 - - - -1.434 - 3.447 0.5 - 518.4 1 2 0 -0.003 19 0 0 0 2.16E+07 1.29E+07 - - - 7.154 1 221125_WJC_METTL3_EV_vs_WT_F08.17653.17653.3 6.46E-07 14/96 K.TQEDPK[136.11]PFC[160.03]VGSAPPSVDVTPTYTK[136.11].D "sp|Q6W2J9|BCOR_HUMAN,tr|H7BZ37|H7BZ37_HUMAN,tr|A1A564|A1A564_HUMAN,tr|H7C2V9|H7C2V9_HUMAN,tr|H7BYY2|H7BYY2_HUMAN,tr|H7C231|H7C231_HUMAN" 6 2736.3287 1.93 120296 17653 3 2736.323345 913.1169 BCL-6 corepressor OS=Homo sapiens OX=9606 GN=BCOR PE=1 SV=1 4.56 2998.4 - 861619 - - - -1.9745 - 2.691 0.56 - 113.4 1 2 0 -0.0054 25 0 0 0 1.28E+08 6.67E+07 - - - 7.0594 0.9999 221125_WJC_METTL3_EV_vs_WT_F08.17654.17654.4 2.10E-11 25/120 K.YKDGTELELKENDIKPLTSFR.Q "sp|Q14739|LBR_HUMAN,tr|A0A494C1L1|A0A494C1L1_HUMAN,tr|C9JXK0|C9JXK0_HUMAN" 3 2495.2908 1.2 120297 17654 4 2495.289662 624.83 Delta(14)-sterol reductase LBR OS=Homo sapiens OX=9606 GN=LBR PE=1 SV=2 4.94 2998.6 - 997919 - - - -0.444 - 3.863 0.616 - 316.4 1 2 2 -0.0011 21 0 0 0 2.61E+07 2.18E+07 - - - 5.0342 0.9998 221125_WJC_METTL3_EV_vs_WT_F08.17655.17655.4 5.89E-06 14/120 K.YK[136.11]DGTELELK[136.11]ENDIK[136.11]PLTSFR[166.11].Q "sp|Q14739|LBR_HUMAN,tr|A0A494C1L1|A0A494C1L1_HUMAN,tr|C9JXK0|C9JXK0_HUMAN" 3 2529.3416 1.2 120298 17655 4 2529.339587 633.3427 Delta(14)-sterol reductase LBR OS=Homo sapiens OX=9606 GN=LBR PE=1 SV=2 4.94 2998.7 - 826031 - - - -0.8117 - 2.748 0.492 - 74.5 1 2 2 -0.0021 21 0 0 0 2.61E+07 2.17E+07 - - - 3.842 0.9999 221125_WJC_METTL3_EV_vs_WT_F08.17659.17659.3 2.86E-08 16/92 R.QQQEEEDLNLEDRGEETVLGGGTR.E sp|Q5T3I0|GPTC4_HUMAN 1 2701.2427 5.26 120300 17659 3 2701.236957 901.4215 G patch domain-containing protein 4 OS=Homo sapiens OX=9606 GN=GPATCH4 PE=1 SV=2 3.94 2999.1 - 1.21E+06 - - - -2.1298 - 3.196 0.638 - 182.9 1 2 1 -0.0058 24 0 0 0 3.37E+07 6.41E+06 - - - 8.3501 0.9744 221125_WJC_METTL3_EV_vs_WT_F08.17669.17669.4 1.01E-05 18/126 N.SDTHSSTFDAGAGIALNDHFVK[136.11].L "sp|P04406|G3P_HUMAN,tr|E7EUT5|E7EUT5_HUMAN" 2 2297.0804 1.29 120304 17669 4 2297.079989 575.2774 Glyceraldehyde-3-phosphate dehydrogenase OS=Homo sapiens OX=9606 GN=GAPDH PE=1 SV=3 5.12 3000.3 - 597067 - - - -0.1741 - 2.68 0.369 - 211.8 1 1 0 -0.0004 22 0 0 0 1.75E+07 1.36E+07 - - - 2.7602 1 221125_WJC_METTL3_EV_vs_WT_F08.17670.17670.3 2.14E-16 26/116 R.GGAVGGEK[136.11]DPPPPGTQGVVYFADDDNTYSR[166.11].E "sp|O94766|B3GA3_HUMAN,tr|G3V150|G3V150_HUMAN" 2 3083.4227 1.69 120305 17670 3 3083.414707 1028.8149 Galactosylgalactosylxylosylprotein 3-beta-glucuronosyltransferase 3 OS=Homo sapiens OX=9606 GN=B3GAT3 PE=1 SV=2 4.04 3000.5 - 349108 - - - -2.6062 - 4.88 0.767 - 561.1 1 2 1 -0.008 30 0 0 0 2.63E+07 1.56E+07 - - - 10.7359 1 221125_WJC_METTL3_EV_vs_WT_F08.17674.17674.3 3.37E-06 19/72 R.EGR[166.11]PSGEAFVELESEDEVK[136.11].L "sp|P31943|HNRH1_HUMAN,tr|E7EQJ0|E7EQJ0_HUMAN,tr|D6RIH9|D6RIH9_HUMAN,tr|D6RJ04|D6RJ04_HUMAN,tr|D6RFM3|D6RFM3_HUMAN,tr|E9PCY7|E9PCY7_HUMAN,tr|D6RIT2|D6RIT2_HUMAN,tr|D6R9T0|D6R9T0_HUMAN,tr|D6RIU0|D6RIU0_HUMAN,tr|D6RAM1|D6RAM1_HUMAN,tr|D6RBM0|D6RBM0_HUMAN,tr|G8JLB6|G8JLB6_HUMAN,tr|D6RDL0|D6RDL0_HUMAN,tr|D6RDU3|D6RDU3_HUMAN,tr|E7EN40|E7EN40_HUMAN" 15 2123.9978 1.67 120307 17674 3 2123.994604 709.0065 Heterogeneous nuclear ribonucleoprotein H OS=Homo sapiens OX=9606 GN=HNRNPH1 PE=1 SV=4 4.06 3001 - 381811 - - - -1.4948 - 3.627 0.571 - 478.4 1 2 0 -0.0032 19 0 0 0 2.16E+07 1.29E+07 - - - 8.0706 0.9805 221125_WJC_METTL3_EV_vs_WT_F08.17675.17675.4 1.85E-06 18/126 N.SDTHSSTFDAGAGIALNDHFVK.L "sp|P04406|G3P_HUMAN,tr|E7EUT5|E7EUT5_HUMAN" 2 2289.0662 1.29 120308 17675 4 2289.058621 573.2738 Glyceraldehyde-3-phosphate dehydrogenase OS=Homo sapiens OX=9606 GN=GAPDH PE=1 SV=3 5.12 3001.1 - 586989 - - - -3.3062 - 3.277 0.475 - 203.3 1 1 0 -0.0076 22 0 0 0 1.75E+07 1.36E+07 - - - 3.7467 1 221125_WJC_METTL3_EV_vs_WT_F08.17679.17679.4 3.91E-06 24/192 R.ESAAPAAAPTAEAPPPSVVTRPEPQALPSPAIR.A "sp|Q92841|DDX17_HUMAN,tr|A0A5H1ZRQ2|A0A5H1ZRQ2_HUMAN,tr|A0A1X7SBZ2|A0A1X7SBZ2_HUMAN" 3 3245.7044 19.46 120310 17679 4 3245.701358 812.4334 Probable ATP-dependent RNA helicase DDX17 OS=Homo sapiens OX=9606 GN=DDX17 PE=1 SV=2 4.79 3001.6 - 838506 - - - -0.9499 - 3.235 0.545 - 186.4 1 2 0 -0.0031 33 0 0 0 2.00E+07 1.03E+06 - - - 4.3211 1 221125_WJC_METTL3_EV_vs_WT_F08.17683.17683.3 2.75E-20 29/116 R.GGAVGGEKDPPPPGTQGVVYFADDDNTYSR.E "sp|O94766|B3GA3_HUMAN,tr|G3V150|G3V150_HUMAN" 2 3065.4003 1.7 120312 17683 3 3065.403303 1022.8074 Galactosylgalactosylxylosylprotein 3-beta-glucuronosyltransferase 3 OS=Homo sapiens OX=9606 GN=B3GAT3 PE=1 SV=2 4.04 3002.2 - 574438 - - - 0.9885 - 5.508 0.796 - 836.6 1 2 1 0.003 30 0 0 0 2.65E+07 1.56E+07 - - - 11.3391 0.9997 221125_WJC_METTL3_EV_vs_WT_F08.17685.17685.4 0.00044 11/108 R.AHIVFDFHQAADGIQEQQR.Q sp|P30520|PURA2_HUMAN 1 2209.0665 0.82 120314 17685 4 2209.06851 553.2739 Adenylosuccinate synthetase isozyme 2 OS=Homo sapiens OX=9606 GN=ADSS2 PE=1 SV=3 5.21 3002.4 - 277954 - - - 0.9262 - 1.978 0.366 - 49 1 2 0 0.002 19 0 0 0 7.04E+06 8.58E+06 - - - 2.6418 0.9741 221125_WJC_METTL3_EV_vs_WT_F08.17686.17686.4 0.00313 Oct-96 Q.FEDVR[166.11]DAEDALHNLDR[166.11]K[136.11].W "sp|O75494|SRS10_HUMAN,tr|Q5JRI1|Q5JRI1_HUMAN" 2 2070.0125 1.91 120315 17686 4 2070.011127 518.5104 Serine\arginine-rich splicing factor 10 OS=Homo sapiens OX=9606 GN=SRSF10 PE=1 SV=1 4.52 3002.6 - 235668 - - - -0.6493 - 1.958 0.472 - 41.9 1 1 1 -0.0013 17 0 0 0 9.72E+06 5.09E+06 - - - 3.5672 1 221125_WJC_METTL3_EV_vs_WT_F08.17690.17690.4 1.15E-12 26/150 T.VAAFASSLVSGLNSSASEPAK[136.11]EPAK[136.11]K[136.11].S "sp|Q86U44|MTA70_HUMAN,tr|F5H6D8|F5H6D8_HUMAN,tr|H0YFV6|H0YFV6_HUMAN,tr|B4DTN4|B4DTN4_HUMAN" 4 2569.3814 0 120316 17690 4 2569.378497 643.3526 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 8.47 3003.2 - 896038 - - - -1.1228 - 4.605 0.648 - 436.7 1 1 1 -0.0029 26 0 0 0 1.89E+05 4.18E+07 - - - 5.3471 0.9896 221125_WJC_METTL3_EV_vs_WT_F08.17692.17692.4 7.92E-07 22/180 D.SPVPTAPTSGGPK[136.11]PSTASAVPELATDPELEK[136.11].K "sp|Q86U44|MTA70_HUMAN,tr|B4E349|B4E349_HUMAN,tr|F5H6D8|F5H6D8_HUMAN,tr|B4DTN4|B4DTN4_HUMAN" 4 3046.5681 0 120317 17692 4 3046.564568 762.6493 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 4.41 3003.4 - 953225 - - - -1.1682 - 3.232 0.424 - 161 1 1 0 -0.0036 31 0 0 0 1.50E+05 4.12E+07 - - - 3.272 0.9998 221125_WJC_METTL3_EV_vs_WT_F08.17693.17693.4 5.51E-06 13/102 R.QEFAQHANAFHQWIQETR.T "sp|Q13813|SPTN1_HUMAN,tr|A0A0D9SF54|A0A0D9SF54_HUMAN,tr|A0A0D9SGF6|A0A0D9SGF6_HUMAN" 3 2240.0511 0.91 120318 17693 4 2240.056548 561.0201 "Spectrin alpha chain, non-erythrocytic 1 OS=Homo sapiens OX=9606 GN=SPTAN1 PE=1 SV=3" 6 3003.5 - 412747 - - - 2.4107 - 2.652 0.432 - 179 1 2 0 0.0054 18 0 0 0 1.25E+07 1.38E+07 - - - 3.3187 0.9999 221125_WJC_METTL3_EV_vs_WT_F08.17694.17694.4 1.75E-08 20/126 R.GSDALSETSSVSHIEDLEKVER.L "sp|Q6P996|PDXD1_HUMAN,tr|H3BND4|H3BND4_HUMAN" 2 2387.1452 0.56 120319 17694 4 2387.139718 597.7936 Pyridoxal-dependent decarboxylase domain-containing protein 1 OS=Homo sapiens OX=9606 GN=PDXDC1 PE=1 SV=2 4.35 3003.6 - 506001 - - - -2.3078 - 4.244 0.591 - 244.9 1 2 1 -0.0055 22 0 0 0 1.03E+07 1.84E+07 - - - 4.8415 0.9974 221125_WJC_METTL3_EV_vs_WT_F08.17697.17697.4 0.00358 8/108 R.GLLQDDAHPTLVTYADHSK[136.11].L "sp|Q86U44|MTA70_HUMAN,tr|F5H6D8|F5H6D8_HUMAN,tr|H0YFV6|H0YFV6_HUMAN,tr|B4DTN4|B4DTN4_HUMAN" 4 2088.0367 0.02 120322 17697 4 2088.042759 523.0165 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 5.13 3004 - 198160 - - - 2.886 - 2.013 0.302 - 53.7 1 2 0 0.006 19 0 0 0 2.99E+05 1.98E+07 - - - 2.0896 1 221125_WJC_METTL3_EV_vs_WT_F08.17698.17698.4 5.90E-05 11/108 K.KESSVGGEDLDSYPDFLHK.M "sp|Q9H582|ZN644_HUMAN,tr|A0A087WZL9|A0A087WZL9_HUMAN" 2 2121.9855 0.71 120323 17698 4 2121.985099 531.5036 Zinc finger protein 644 OS=Homo sapiens OX=9606 GN=ZNF644 PE=1 SV=2 4.43 3004.2 - 183302 - - - -0.1791 - 2.185 0.506 - 75.6 1 2 0 -0.0004 19 0 0 0 3.72E+06 5.20E+06 - - - 3.8945 0.9999 221125_WJC_METTL3_EV_vs_WT_F08.17701.17701.4 5.18E-08 17/120 K.EAMEDGEIDGNK[136.11]VTLDWAK[136.11]PK[136.11].G "sp|P19338|NUCL_HUMAN,tr|A0A7I2V699|A0A7I2V699_HUMAN,tr|A0A7I2V3F3|A0A7I2V3F3_HUMAN,tr|A0A7I2V428|A0A7I2V428_HUMAN,tr|H7BY16|H7BY16_HUMAN,tr|C9JLB1|C9JLB1_HUMAN" 6 2369.1635 1.04 120324 17701 4 2369.165606 593.2982 Nucleolin OS=Homo sapiens OX=9606 GN=NCL PE=1 SV=3 4.3 3004.6 - 1.02E+06 - - - 0.8775 - 3.022 0.557 - 204.5 1 2 1 0.0021 21 0 0 0 3.93E+07 3.79E+07 - - - 4.4392 0.9999 221125_WJC_METTL3_EV_vs_WT_F08.17712.17712.3 3.63E-05 16/128 R.ESAAPAAAPTAEAPPPSVVTRPEPQALPSPAIR.A "sp|Q92841|DDX17_HUMAN,tr|A0A5H1ZRQ2|A0A5H1ZRQ2_HUMAN,tr|A0A1X7SBZ2|A0A1X7SBZ2_HUMAN" 3 3245.7044 999 120331 17712 3 3245.709884 1082.9088 Probable ATP-dependent RNA helicase DDX17 OS=Homo sapiens OX=9606 GN=DDX17 PE=1 SV=2 4.79 3006.1 - 736507 - - - 1.677 - 2.293 0.521 - 66.7 1 2 0 0.0054 33 0 0 0 2.80E+07 0.00E+00 - - - 6.2563 1 221125_WJC_METTL3_EV_vs_WT_F08.17722.17722.3 7.33E-10 17/80 K.EAMEDGEIDGNK[136.11]VTLDWAK[136.11]PK[136.11].G "sp|P19338|NUCL_HUMAN,tr|A0A7I2V699|A0A7I2V699_HUMAN,tr|A0A7I2V3F3|A0A7I2V3F3_HUMAN,tr|A0A7I2V428|A0A7I2V428_HUMAN,tr|H7BY16|H7BY16_HUMAN,tr|C9JLB1|C9JLB1_HUMAN" 6 2369.1635 0.6 120337 17722 3 2369.161317 790.7285 Nucleolin OS=Homo sapiens OX=9606 GN=NCL PE=1 SV=3 4.3 3007.4 - 468135 - - - -0.9328 - 3.669 0.665 - 304.9 1 2 1 -0.0022 21 0 0 0 8.06E+06 1.35E+07 - - - 9.07 1 221125_WJC_METTL3_EV_vs_WT_F08.17729.17729.3 2.58E-12 19/72 R.YHTSQSGDEMTSLSEYVSR[166.11].M sp|P08238|HS90B_HUMAN 1 2185.9461 0.74 120342 17729 3 2185.942109 729.656 Heat shock protein HSP 90-beta OS=Homo sapiens OX=9606 GN=HSP90AB1 PE=1 SV=4 4.65 3008.5 - 299378 - - - -1.8473 - 3.571 0.707 - 464.3 1 2 0 -0.004 19 0 0 0 5.34E+07 7.25E+07 - - - 9.5484 0.9986 221125_WJC_METTL3_EV_vs_WT_F08.17737.17737.4 2.79E-07 20/228 R.IFPPETSASVAATPPPSTASAPAAVNSSASADK[136.11]PLSNMK[136.11].L "sp|P09874|PARP1_HUMAN,tr|A0A7I2V3E1|A0A7I2V3E1_HUMAN" 2 3782.9008 1.52 120346 17737 4 3783.900235 946.7325 Poly [ADP-ribose] polymerase 1 OS=Homo sapiens OX=9606 GN=PARP1 PE=1 SV=4 6.07 3009.5 - 449156 - - - 264.2057 - 4.076 0.487 - 118.9 1 2 0 0.9995 39 0 0 0 3.23E+07 2.13E+07 - - - 3.5956 1 221125_WJC_METTL3_EV_vs_WT_F08.17739.17739.4 4.72E-09 17/138 K.K[136.11]AELLDNEK[136.11]PAAVVAPITTGYTVK[136.11].L sp|Q9HB71|CYBP_HUMAN 1 2551.4324 0.26 120348 17739 4 2551.433465 638.8654 Calcyclin-binding protein OS=Homo sapiens OX=9606 GN=CACYBP PE=1 SV=2 6.18 3009.7 - 293736 - - - 0.435 - 3.579 0.545 - 149.9 1 2 0 0.0011 24 0 0 0 2.02E+06 7.70E+06 - - - 4.3786 1 221125_WJC_METTL3_EV_vs_WT_F08.17745.17745.3 1.30E-10 19/72 R.YHTSQSGDEMTSLSEYVSR.M sp|P08238|HS90B_HUMAN 1 2175.9379 0.74 120352 17745 3 2175.937518 726.3199 Heat shock protein HSP 90-beta OS=Homo sapiens OX=9606 GN=HSP90AB1 PE=1 SV=4 4.65 3010.5 - 684002 - - - -0.165 - 3.855 0.694 - 451.4 1 2 0 -0.0004 19 0 0 0 5.35E+07 7.25E+07 - - - 9.5925 0.9992 221125_WJC_METTL3_EV_vs_WT_F08.17746.17746.3 8.44E-06 14/80 K.EAMEDGEIDGNKVTLDWAKPK.G "sp|P19338|NUCL_HUMAN,tr|A0A7I2V699|A0A7I2V699_HUMAN,tr|A0A7I2V3F3|A0A7I2V3F3_HUMAN,tr|A0A7I2V428|A0A7I2V428_HUMAN,tr|H7BY16|H7BY16_HUMAN,tr|C9JLB1|C9JLB1_HUMAN" 6 2345.1209 0.65 120353 17746 3 2345.127792 782.7143 Nucleolin OS=Homo sapiens OX=9606 GN=NCL PE=1 SV=3 4.3 3010.6 - 469264 - - - 2.9274 - 2.46 0.468 - 205.7 1 2 1 0.0069 21 0 0 0 8.06E+06 1.25E+07 - - - 5.9139 1 221125_WJC_METTL3_EV_vs_WT_F08.17752.17752.3 8.56E-11 17/104 R.R[166.11]GAYGGGYGGYDDYNGYNDGYGFGSDR[166.11].F "sp|P31943|HNRH1_HUMAN,tr|H0YBD7|H0YBD7_HUMAN,tr|H0YB39|H0YB39_HUMAN,tr|E9PCY7|E9PCY7_HUMAN,tr|G8JLB6|G8JLB6_HUMAN" 5 2892.1551 1.46 120357 17752 3 2892.160847 965.059 Heterogeneous nuclear ribonucleoprotein H OS=Homo sapiens OX=9606 GN=HNRNPH1 PE=1 SV=4 4.14 3011.4 - 177938 - - - 1.9805 - 3.566 0.809 - 273 1 2 0 0.0057 27 0 0 0 1.90E+06 1.30E+06 - - - 10.4831 0.9994 221125_WJC_METTL3_EV_vs_WT_F08.17755.17755.4 3.33E-05 13/120 K.TSLK[136.11]EDEDK[136.11]SGPIFIVVPNGK[136.11].E sp|Q14008|CKAP5_HUMAN 1 2296.2377 1.1 120360 17755 4 2296.244138 575.0667 Cytoskeleton-associated protein 5 OS=Homo sapiens OX=9606 GN=CKAP5 PE=1 SV=3 4.78 3011.8 - 208552 - - - 2.8133 - 2.886 0.456 - 84.1 1 2 2 0.0065 21 0 0 0 3.58E+07 3.26E+07 - - - 3.5437 0.998 221125_WJC_METTL3_EV_vs_WT_F08.17770.17770.3 0.000117 Sep-52 R.IVATKPLYVALAQR.K "sp|Q9H361|PABP3_HUMAN,sp|P11940|PABP1_HUMAN,tr|A0A7I2YQE4|A0A7I2YQE4_HUMAN,tr|A0A7I2V649|A0A7I2V649_HUMAN,tr|H0YB86|H0YB86_HUMAN,tr|H0YAR2|H0YAR2_HUMAN,tr|E7ERJ7|E7ERJ7_HUMAN,tr|A0A7I2YQ88|A0A7I2YQ88_HUMAN,tr|A0A087WTT1|A0A087WTT1_HUMAN,tr|A0A7I2YQ90|A0A7I2YQ90_HUMAN,tr|A0A7I2V4N4|A0A7I2V4N4_HUMAN,tr|E7EQV3|E7EQV3_HUMAN" 12 1541.9293 1.37 120370 17770 3 1541.936189 514.9837 Polyadenylate-binding protein 3 OS=Homo sapiens OX=9606 GN=PABPC3 PE=1 SV=2 9.99 3013.6 - 136468 - - - 4.436 - 1.815 0.405 - 90.4 1 2 0 0.0068 14 0 0 0 4.61E+06 3.35E+06 - - - 4.6376 0.9983 221125_WJC_METTL3_EV_vs_WT_F08.17776.17776.3 2.35E-08 23/120 D.SPVPTAPTSGGPK[136.11]PSTASAVPELATDPELEK[136.11].K "sp|Q86U44|MTA70_HUMAN,tr|B4E349|B4E349_HUMAN,tr|F5H6D8|F5H6D8_HUMAN,tr|B4DTN4|B4DTN4_HUMAN" 4 3046.5681 0.001 120373 17776 3 3046.566771 1016.53 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 4.41 3014.5 - 1.83E+06 - - - -0.4451 - 3.403 0.54 - 193.6 1 1 0 -0.0014 31 0 0 0 0.00E+00 2.19E+08 - - - 7.3776 0.9999 221125_WJC_METTL3_EV_vs_WT_F08.17785.17785.3 7.75E-09 19/72 K.SKELTTEIDNNIEQISSYK.S "sp|P13645|K1C10_HUMAN,tr|A0A1B0GVI3|A0A1B0GVI3_HUMAN" 2 2211.0907 1301.42 120378 17785 3 2211.095375 738.0375 "Keratin, type I cytoskeletal 10 OS=Homo sapiens OX=9606 GN=KRT10 PE=1 SV=6" 4.41 3015.6 - 963535 - - - 2.1266 - 3.836 0.591 - 357.5 1 2 1 0.0047 19 0 0 0 3.61E+08 2.78E+05 - - - 8.4308 0.9997 221125_WJC_METTL3_EV_vs_WT_F08.17788.17788.4 5.80E-07 17/120 K.TSLKEDEDKSGPIFIVVPNGK.E sp|Q14008|CKAP5_HUMAN 1 2272.1951 1.09 120380 17788 4 2272.198747 569.056 Cytoskeleton-associated protein 5 OS=Homo sapiens OX=9606 GN=CKAP5 PE=1 SV=3 4.78 3015.9 - 1.03E+06 - - - 1.6147 - 2.805 0.46 - 146.2 1 2 2 0.0037 21 0 0 0 3.59E+07 3.28E+07 - - - 3.5698 1 221125_WJC_METTL3_EV_vs_WT_F08.17794.17794.4 1.78E-10 19/144 R.IHQIGPGMVQQIQSVC[160.03]MEC[160.03]QGHGER[166.11].L sp|P31689|DNJA1_HUMAN 1 2888.3178 0.39 120384 17794 4 2888.31606 723.0867 DnaJ homolog subfamily A member 1 OS=Homo sapiens OX=9606 GN=DNAJA1 PE=1 SV=2 6 3016.7 - 433051 - - - -0.5945 - 3.846 0.66 - 227.8 1 2 0 -0.0017 25 0 0 0 8.71E+06 2.23E+07 - - - 5.3987 0.9998 221125_WJC_METTL3_EV_vs_WT_F08.17796.17796.4 3.16E-06 20/120 R.QLFHPEQLITGK[136.11]EDAANNYAR[166.11].G "sp|Q9NY65|TBA8_HUMAN,sp|P0DPH7|TBA3C_HUMAN,sp|Q71U36|TBA1A_HUMAN,sp|P0DPH8|TBA3D_HUMAN,sp|P68366|TBA4A_HUMAN,sp|P68363|TBA1B_HUMAN,sp|Q9BQE3|TBA1C_HUMAN,tr|C9JJQ8|C9JJQ8_HUMAN,tr|F8VS66|F8VS66_HUMAN,tr|F8VWV9|F8VWV9_HUMAN,tr|F8VRZ4|F8VRZ4_HUMAN,tr|F8VVB9|F8VVB9_HUMAN,tr|C9JQ00|C9JQ00_HUMAN,tr|C9JEV8|C9JEV8_HUMAN,tr|A0A7P0TA31|A0A7P0TA31_HUMAN,tr|A0A1W2PQM2|A0A1W2PQM2_HUMAN,tr|F5H5D3|F5H5D3_HUMAN,tr|C9J2C0|C9J2C0_HUMAN,tr|C9K0S6|C9K0S6_HUMAN,tr|C9JDL2|C9JDL2_HUMAN,tr|F8VQQ4|F8VQQ4_HUMAN,tr|F8VX09|F8VX09_HUMAN,tr|A0A7P0T945|A0A7P0T945_HUMAN" 23 2432.2203 1.07 120386 17796 4 2432.222996 609.0624 Tubulin alpha-8 chain OS=Homo sapiens OX=9606 GN=TUBA8 PE=1 SV=1 5.45 3016.9 - 1.34E+06 - - - 1.0912 - 3.834 0.471 - 408 1 2 1 0.0027 21 0 0 0 9.53E+07 8.93E+07 - - - 3.7692 0.9999 221125_WJC_METTL3_EV_vs_WT_F08.17800.17800.3 8.79E-12 24/80 R.QLFHPEQLITGK[136.11]EDAANNYAR[166.11].G "sp|Q9NY65|TBA8_HUMAN,sp|P0DPH7|TBA3C_HUMAN,sp|Q71U36|TBA1A_HUMAN,sp|P0DPH8|TBA3D_HUMAN,sp|P68366|TBA4A_HUMAN,sp|P68363|TBA1B_HUMAN,sp|Q9BQE3|TBA1C_HUMAN,tr|C9JJQ8|C9JJQ8_HUMAN,tr|F8VS66|F8VS66_HUMAN,tr|F8VWV9|F8VWV9_HUMAN,tr|F8VRZ4|F8VRZ4_HUMAN,tr|F8VVB9|F8VVB9_HUMAN,tr|C9JQ00|C9JQ00_HUMAN,tr|C9JEV8|C9JEV8_HUMAN,tr|A0A7P0TA31|A0A7P0TA31_HUMAN,tr|A0A1W2PQM2|A0A1W2PQM2_HUMAN,tr|F5H5D3|F5H5D3_HUMAN,tr|C9J2C0|C9J2C0_HUMAN,tr|C9K0S6|C9K0S6_HUMAN,tr|C9JDL2|C9JDL2_HUMAN,tr|F8VQQ4|F8VQQ4_HUMAN,tr|F8VX09|F8VX09_HUMAN,tr|A0A7P0T945|A0A7P0T945_HUMAN" 23 2432.2203 0.6 120388 17800 3 2432.223238 811.7474 Tubulin alpha-8 chain OS=Homo sapiens OX=9606 GN=TUBA8 PE=1 SV=1 5.45 3017.4 - 527058 - - - 1.1907 - 3.994 0.577 - 835.2 1 2 1 0.0029 21 0 0 0 1.87E+07 3.13E+07 - - - 8.2922 0.9992 221125_WJC_METTL3_EV_vs_WT_F08.17801.17801.3 0.00139 Aug-52 K.K[136.11]GPGEVAGTVTGQK[136.11].R "sp|Q86U44|MTA70_HUMAN,tr|F5H6D8|F5H6D8_HUMAN,tr|H0YFV6|H0YFV6_HUMAN,tr|B4DTN4|B4DTN4_HUMAN" 4 1343.738 0.001 120389 17801 3 1343.735535 448.9199 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 8.59 3017.6 - 225075 - - - -1.8188 - 1.654 0.357 - 86.8 1 2 0 -0.0024 14 0 0 0 0.00E+00 6.41E+06 - - - 3.8568 0.7956 221125_WJC_METTL3_EV_vs_WT_F08.17802.17802.4 0.128 9/180 R.SGGGGSSVSGGGGGGGAGAGGC[160.03]GGPGGALTR[166.11].R "sp|Q8N594|MPND_HUMAN,tr|W4VSR2|W4VSR2_HUMAN,tr|M0R044|M0R044_HUMAN,tr|M0R189|M0R189_HUMAN,tr|M0R0F2|M0R0F2_HUMAN" 5 2342.0293 0.04 120390 17802 4 2342.025401 586.5146 MPN domain-containing protein OS=Homo sapiens OX=9606 GN=MPND PE=1 SV=1 7.96 3017.6 - 1.60E+06 - - - -1.6721 - 1.677 0.153 - 17.4 5 2 0 -0.0039 31 0 0 0 1.38E+06 3.10E+07 - - - 0.181 1 221125_WJC_METTL3_EV_vs_WT_F08.17811.17811.3 2.51E-12 18/84 K.ENQHVQQTLNSTNEIEALETSR[166.11].L sp|Q9UKT4|FBX5_HUMAN 1 2550.2186 0.44 120397 17811 3 2551.219133 851.0801 F-box only protein 5 OS=Homo sapiens OX=9606 GN=FBXO5 PE=1 SV=1 4.48 3018.8 - 364298 - - - 392.3491 - 3.792 0.653 - 253.3 1 2 0 1.0006 22 0 0 0 2.53E+06 5.82E+06 - - - 8.7032 0.9999 221125_WJC_METTL3_EV_vs_WT_F08.17816.17816.4 6.24E-09 21/132 K.VKADRDESSPYAAMLAAQDVAQR.C "sp|P62263|RS14_HUMAN,tr|A0A2R8Y811|A0A2R8Y811_HUMAN,tr|E5RH77|E5RH77_HUMAN" 3 2491.2125 1.23 120400 17816 4 2491.214686 623.8104 40S ribosomal protein S14 OS=Homo sapiens OX=9606 GN=RPS14 PE=1 SV=3 4.68 3019.5 - 618959 - - - 0.863 - 3.846 0.585 - 340.8 1 2 2 0.0022 23 0 0 0 2.48E+09 2.01E+09 - - - 4.7537 1 221125_WJC_METTL3_EV_vs_WT_F08.17821.17821.3 2.23E-09 30/124 R.LQAALDDEEAGGRPAMEPGNGSLDLGGDSAGR.S "sp|Q00839|HNRPU_HUMAN,tr|A0A1W2PPS1|A0A1W2PPS1_HUMAN,tr|A0A1X7SBS1|A0A1X7SBS1_HUMAN" 3 3125.432 1.31 120402 17821 3 3125.425903 1042.8179 Heterogeneous nuclear ribonucleoprotein U OS=Homo sapiens OX=9606 GN=HNRNPU PE=1 SV=6 3.9 3020.1 - 1.51E+06 - - - -1.9457 - 4.717 0.712 - 786.4 1 2 0 -0.0061 32 0 0 0 3.31E+08 2.53E+08 - - - 10.0451 1 221125_WJC_METTL3_EV_vs_WT_F08.17823.17823.4 5.58E-08 17/102 R.NHIENQDEC[160.03]VLNVISHAR[166.11].L "sp|Q9BZE1|RM37_HUMAN,tr|S4R369|S4R369_HUMAN" 2 2157.0261 1.37 120404 17823 4 2157.020608 540.2638 "39S ribosomal protein L37, mitochondrial OS=Homo sapiens OX=9606 GN=MRPL37 PE=1 SV=2" 5.27 3020.4 - 366517 - - - -2.5317 - 3.018 0.6 - 265.4 1 2 0 -0.0055 18 0 0 0 1.18E+07 8.62E+06 - - - 4.8253 0.9996 221125_WJC_METTL3_EV_vs_WT_F08.17827.17827.3 3.64E-05 14/56 R.STSHK[136.11]PDEIYGMIER[166.11].L sp|Q86U44|MTA70_HUMAN 1 1779.8581 0.01 120405 17827 3 1779.85132 594.2933 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 5.42 3020.9 - 395364 - - - -3.7834 - 2.701 0.408 - 269.5 1 2 0 -0.0067 15 0 0 0 1.83E+05 1.57E+07 - - - 5.6797 0.9999 221125_WJC_METTL3_EV_vs_WT_F08.17829.17829.4 7.38E-10 24/132 K.VK[136.11]ADR[166.11]DESSPYAAMLAAQDVAQR[166.11].C "sp|P62263|RS14_HUMAN,tr|A0A2R8Y811|A0A2R8Y811_HUMAN,tr|E5RH77|E5RH77_HUMAN" 3 2519.2433 1.23 120407 17829 4 2519.24048 630.8181 40S ribosomal protein S14 OS=Homo sapiens OX=9606 GN=RPS14 PE=1 SV=3 4.68 3021.2 - 1.45E+06 - - - -1.1099 - 3.952 0.539 - 379.9 1 2 2 -0.0028 23 0 0 0 2.48E+09 2.01E+09 - - - 4.3619 1 221125_WJC_METTL3_EV_vs_WT_F08.17836.17836.3 1.04E-14 26/68 R.NHIENQDEC[160.03]VLNVISHAR.L "sp|Q9BZE1|RM37_HUMAN,tr|S4R369|S4R369_HUMAN" 2 2147.0178 1.14 120411 17836 3 2147.01178 716.6799 "39S ribosomal protein L37, mitochondrial OS=Homo sapiens OX=9606 GN=MRPL37 PE=1 SV=2" 5.27 3022 - 745381 - - - -2.8034 - 4.158 0.723 - 1165.6 1 2 0 -0.006 18 0 0 0 2.48E+07 2.18E+07 - - - 10.1475 0.9995 221125_WJC_METTL3_EV_vs_WT_F08.17838.17838.4 9.27E-06 16/114 R.DSDKRPSLGLAPGGLAVVGR.S "sp|O95785|WIZ_HUMAN,tr|A0A669KBG4|A0A669KBG4_HUMAN,tr|A0A2R8YFV2|A0A2R8YFV2_HUMAN,tr|A0A669KAV7|A0A669KAV7_HUMAN,tr|M0QXA7|M0QXA7_HUMAN,tr|A0A669KBH9|A0A669KBH9_HUMAN,tr|B9EGQ5|B9EGQ5_HUMAN" 7 1964.0803 1.51 120413 17838 4 1964.076329 492.0274 Protein Wiz OS=Homo sapiens OX=9606 GN=WIZ PE=1 SV=2 8.75 3022.3 - 506098 - - - -2.0335 - 3.098 0.423 - 168.4 1 2 1 -0.004 20 0 0 0 7.42E+06 4.93E+06 - - - 3.2847 1 221125_WJC_METTL3_EV_vs_WT_F08.17842.17842.4 1.31E-07 19/186 R.LQAALDDEEAGGRPAMEPGNGSLDLGGDSAGR.S "sp|Q00839|HNRPU_HUMAN,tr|A0A1W2PPS1|A0A1W2PPS1_HUMAN,tr|A0A1X7SBS1|A0A1X7SBS1_HUMAN" 3 3125.432 1.22 120415 17842 4 3125.428353 782.3653 Heterogeneous nuclear ribonucleoprotein U OS=Homo sapiens OX=9606 GN=HNRNPU PE=1 SV=6 3.9 3022.8 - 2.66E+06 - - - -1.1618 - 3.364 0.598 - 143.2 1 2 0 -0.0036 32 0 0 0 6.90E+07 5.66E+07 - - - 4.7963 1 221125_WJC_METTL3_EV_vs_WT_F08.17845.17845.3 7.52E-13 24/88 K.VK[136.11]ADR[166.11]DESSPYAAMLAAQDVAQR[166.11].C "sp|P62263|RS14_HUMAN,tr|A0A2R8Y811|A0A2R8Y811_HUMAN,tr|E5RH77|E5RH77_HUMAN" 3 2519.2433 1.1 120418 17845 3 2519.240384 840.755 40S ribosomal protein S14 OS=Homo sapiens OX=9606 GN=RPS14 PE=1 SV=3 4.68 3023.2 - 827114 - - - -1.148 - 4.732 0.573 - 741.7 1 2 2 -0.0029 23 0 0 0 5.35E+08 4.89E+08 - - - 8.574 1 221125_WJC_METTL3_EV_vs_WT_F08.17846.17846.3 7.42E-17 25/68 R.NHIENQDEC[160.03]VLNVISHAR[166.11].L "sp|Q9BZE1|RM37_HUMAN,tr|S4R369|S4R369_HUMAN" 2 2157.0261 2.7 120419 17846 3 2157.014678 720.016 "39S ribosomal protein L37, mitochondrial OS=Homo sapiens OX=9606 GN=MRPL37 PE=1 SV=2" 5.27 3023.3 - 501912 - - - -5.2809 - 4.396 0.734 - 1081.8 1 2 0 -0.0114 18 0 0 0 2.29E+07 8.51E+06 - - - 10.4073 1 221125_WJC_METTL3_EV_vs_WT_F08.17861.17861.4 9.98E-07 19/228 R.IFPPETSASVAATPPPSTASAPAAVNSSASADKPLSNMK.L "sp|P09874|PARP1_HUMAN,tr|A0A7I2V3E1|A0A7I2V3E1_HUMAN" 2 3766.8724 2.1 120429 17861 4 3766.868973 942.7254 Poly [ADP-ribose] polymerase 1 OS=Homo sapiens OX=9606 GN=PARP1 PE=1 SV=4 6.07 3025.1 - 1.07E+06 - - - -0.9021 - 3.565 0.477 - 101.7 1 2 0 -0.0034 39 0 0 0 8.59E+06 4.08E+06 - - - 3.7456 0.9999 221125_WJC_METTL3_EV_vs_WT_F08.17863.17863.4 3.79E-08 23/120 R.QLFHPEQLITGKEDAANNYAR.G "sp|Q9NY65|TBA8_HUMAN,sp|P0DPH7|TBA3C_HUMAN,sp|Q71U36|TBA1A_HUMAN,sp|P0DPH8|TBA3D_HUMAN,sp|P68366|TBA4A_HUMAN,sp|P68363|TBA1B_HUMAN,sp|Q9BQE3|TBA1C_HUMAN,tr|C9JJQ8|C9JJQ8_HUMAN,tr|F8VS66|F8VS66_HUMAN,tr|F8VWV9|F8VWV9_HUMAN,tr|F8VRZ4|F8VRZ4_HUMAN,tr|F8VVB9|F8VVB9_HUMAN,tr|C9JQ00|C9JQ00_HUMAN,tr|C9JEV8|C9JEV8_HUMAN,tr|A0A7P0TA31|A0A7P0TA31_HUMAN,tr|A0A1W2PQM2|A0A1W2PQM2_HUMAN,tr|F5H5D3|F5H5D3_HUMAN,tr|C9J2C0|C9J2C0_HUMAN,tr|C9K0S6|C9K0S6_HUMAN,tr|C9JDL2|C9JDL2_HUMAN,tr|F8VQQ4|F8VQQ4_HUMAN,tr|F8VX09|F8VX09_HUMAN,tr|A0A7P0T945|A0A7P0T945_HUMAN" 23 2414.1979 0.7 120430 17863 4 2414.19383 604.5567 Tubulin alpha-8 chain OS=Homo sapiens OX=9606 GN=TUBA8 PE=1 SV=1 5.45 3025.4 - 1.82E+06 - - - -1.6743 - 4.383 0.568 - 548.2 1 2 1 -0.004 21 0 0 0 5.59E+07 7.99E+07 - - - 4.6573 0.9795 221125_WJC_METTL3_EV_vs_WT_F08.17867.17867.2 1.11E-06 Dec-54 R.SDSPVPTAPTSGGPK[136.11]PSTASAVPELATD.P "sp|Q86U44|MTA70_HUMAN,tr|B4E349|B4E349_HUMAN,tr|F5H6D8|F5H6D8_HUMAN,tr|B4DTN4|B4DTN4_HUMAN" 4 2644.2959 0.001 120432 17867 2 2644.289403 1323.1552 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 4.27 3025.9 - 831736 - - - -2.4649 - 2.097 0.553 - 147 1 1 0 -0.0065 28 0 0 0 0.00E+00 1.82E+07 - - - 4.944 0.9998 221125_WJC_METTL3_EV_vs_WT_F08.17870.17870.4 0.00151 13/84 R.STSHK[136.11]PDEIYGMIER[166.11].L sp|Q86U44|MTA70_HUMAN 1 1779.8581 0.001 120433 17870 4 1779.8543 445.9718 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 5.42 3026.3 - 398165 - - - -2.1092 - 1.951 0.41 - 66.7 1 2 0 -0.0038 15 0 0 0 0.00E+00 9.44E+06 - - - 3.0327 0.9992 221125_WJC_METTL3_EV_vs_WT_F08.17872.17872.2 0.000572 28-Dec R.GALQNIIPASTGAAK[136.11].A "sp|P04406|G3P_HUMAN,tr|E7EUT5|E7EUT5_HUMAN" 2 1418.7973 1.26 120434 17872 2 1418.792285 710.4059 Glyceraldehyde-3-phosphate dehydrogenase OS=Homo sapiens OX=9606 GN=GAPDH PE=1 SV=3 8.75 3026.5 - 311533 - - - -3.5192 - 2.489 0.486 - 304.7 1 2 0 -0.005 15 0 0 0 2.41E+07 1.91E+07 - - - 4.8709 1 221125_WJC_METTL3_EV_vs_WT_F08.17883.17883.3 9.16E-06 30/88 K.VKADRDESSPYAAMLAAQDVAQR.C "sp|P62263|RS14_HUMAN,tr|A0A2R8Y811|A0A2R8Y811_HUMAN,tr|E5RH77|E5RH77_HUMAN" 3 2491.2125 1.1 120440 17883 3 2491.208571 831.4115 40S ribosomal protein S14 OS=Homo sapiens OX=9606 GN=RPS14 PE=1 SV=3 4.68 3027.9 - 7.67E+06 - - - -1.5916 - 5.017 0.586 - 1136.1 1 2 2 -0.004 23 0 0 0 5.35E+08 4.88E+08 - - - 8.8558 1 221125_WJC_METTL3_EV_vs_WT_F08.17884.17884.4 8.54E-08 29/186 R.LQAALDDEEAGGR[166.11]PAMEPGNGSLDLGGDSAGR[166.11].S "sp|Q00839|HNRPU_HUMAN,tr|A0A1W2PPS1|A0A1W2PPS1_HUMAN,tr|A0A1X7SBS1|A0A1X7SBS1_HUMAN" 3 3145.4485 1.21 120441 17884 4 3145.441032 787.3694 Heterogeneous nuclear ribonucleoprotein U OS=Homo sapiens OX=9606 GN=HNRNPU PE=1 SV=6 3.9 3028.1 - 1.58E+06 - - - -2.3819 - 3.402 0.58 - 304 1 2 0 -0.0075 32 0 0 0 6.90E+07 5.71E+07 - - - 4.6419 0.9999 221125_WJC_METTL3_EV_vs_WT_F08.17886.17886.2 2.37E-06 28-Nov R.GALQNIIPASTGAAK.A "sp|P04406|G3P_HUMAN,tr|E7EUT5|E7EUT5_HUMAN" 2 1410.7831 1.25 120443 17886 2 1410.782112 706.3988 Glyceraldehyde-3-phosphate dehydrogenase OS=Homo sapiens OX=9606 GN=GAPDH PE=1 SV=3 8.75 3028.3 - 398710 - - - -0.6847 - 2.19 0.5 - 264.8 1 2 0 -0.001 15 0 0 0 2.41E+07 1.93E+07 - - - 4.661 1 221125_WJC_METTL3_EV_vs_WT_F08.17894.17894.3 3.25E-11 32/124 R.LQAALDDEEAGGR[166.11]PAMEPGNGSLDLGGDSAGR[166.11].S "sp|Q00839|HNRPU_HUMAN,tr|A0A1W2PPS1|A0A1W2PPS1_HUMAN,tr|A0A1X7SBS1|A0A1X7SBS1_HUMAN" 3 3145.4485 1.31 120447 17894 3 3145.444718 1049.4901 Heterogeneous nuclear ribonucleoprotein U OS=Homo sapiens OX=9606 GN=HNRNPU PE=1 SV=6 3.9 3029.4 - 2.40E+06 - - - -1.21 - 4.865 0.645 - 909.6 1 2 0 -0.0038 32 0 0 0 3.31E+08 2.53E+08 - - - 9.3698 0.9966 221125_WJC_METTL3_EV_vs_WT_F08.17895.17895.3 9.05E-08 14/76 L.VSSHSDNESLGGFSIEDVQK.E "sp|Q8IWS0|PHF6_HUMAN,tr|Q5JRC6|Q5JRC6_HUMAN,tr|A0A0D9SGE8|A0A0D9SGE8_HUMAN" 3 2133.9815 1.23 120448 17895 3 2133.975824 712.3344 PHD finger protein 6 OS=Homo sapiens OX=9606 GN=PHF6 PE=1 SV=1 4.31 3029.5 - 567119 - - - -2.6397 - 3.189 0.598 - 224.4 1 1 0 -0.0056 20 0 0 0 1.75E+07 1.42E+07 - - - 8.019 1 221125_WJC_METTL3_EV_vs_WT_F08.17896.17896.3 7.88E-09 14/52 K.HGYIGEFEIIDDHR[166.11].A "sp|P62244|RS15A_HUMAN,tr|I3L246|I3L246_HUMAN,tr|I3L3P7|I3L3P7_HUMAN,tr|H3BN98|H3BN98_HUMAN" 4 1709.8037 0.99 120449 17896 3 1709.801671 570.9418 40S ribosomal protein S15a OS=Homo sapiens OX=9606 GN=RPS15A PE=1 SV=2 4.72 3029.6 - 552992 - - - -1.189 - 2.968 0.588 - 302 1 2 0 -0.002 14 0 0 0 9.78E+06 9.85E+06 - - - 7.9862 1 221125_WJC_METTL3_EV_vs_WT_F08.17906.17906.4 1.47E-11 26/114 K.AR[166.11]PFPDGLAEDIDK[136.11]GEVSAR[166.11].Q sp|P13639|EF2_HUMAN 1 2170.1013 0.53 120455 17906 4 2170.09697 543.5326 Elongation factor 2 OS=Homo sapiens OX=9606 GN=EEF2 PE=1 SV=4 4.44 3030.8 - 369535 - - - -1.9888 - 4.591 0.613 - 653 1 2 1 -0.0043 20 0 0 0 5.91E+06 1.11E+07 - - - 5.0699 1 221125_WJC_METTL3_EV_vs_WT_F08.17907.17907.3 6.00E-14 23/84 K.TKEQVTNVGGAVVTGVTAVAQK.T "sp|P37840|SYUA_HUMAN,tr|A0A669KB41|A0A669KB41_HUMAN,tr|A0A669KBH5|A0A669KBH5_HUMAN,tr|H6UYS7|H6UYS7_HUMAN,tr|E7EPV7|E7EPV7_HUMAN" 5 2156.1801 1.59 120456 17907 3 2156.177093 719.734 Alpha-synuclein OS=Homo sapiens OX=9606 GN=SNCA PE=1 SV=1 8.26 3031 - 648700 - - - -1.3932 - 4.138 0.626 - 692.6 1 2 1 -0.003 22 0 0 0 3.60E+09 2.26E+09 - - - 8.8855 0.9999 221125_WJC_METTL3_EV_vs_WT_F08.17912.17912.3 5.14E-08 24/84 K.TK[136.11]EQVTNVGGAVVTGVTAVAQK[136.11].T "sp|P37840|SYUA_HUMAN,tr|A0A669KB41|A0A669KB41_HUMAN,tr|A0A669KBH5|A0A669KBH5_HUMAN,tr|H6UYS7|H6UYS7_HUMAN,tr|E7EPV7|E7EPV7_HUMAN" 5 2172.2085 1.59 120459 17912 3 2172.205825 725.0768 Alpha-synuclein OS=Homo sapiens OX=9606 GN=SNCA PE=1 SV=1 8.26 3031.6 - 1.23E+06 - - - -1.2301 - 3.528 0.523 - 242.9 1 2 1 -0.0027 22 0 0 0 3.60E+09 2.26E+09 - - - 7.3592 0.9998 221125_WJC_METTL3_EV_vs_WT_F08.17926.17926.4 8.46E-08 20/126 K.TKEQVTNVGGAVVTGVTAVAQK.T "sp|P37840|SYUA_HUMAN,tr|A0A669KB41|A0A669KB41_HUMAN,tr|A0A669KBH5|A0A669KBH5_HUMAN,tr|H6UYS7|H6UYS7_HUMAN,tr|E7EPV7|E7EPV7_HUMAN" 5 2156.1801 1.65 120466 17926 4 2156.174931 540.0523 Alpha-synuclein OS=Homo sapiens OX=9606 GN=SNCA PE=1 SV=1 8.26 3033.3 - 972323 - - - -2.3959 - 3.462 0.528 - 292.1 1 2 1 -0.0052 22 0 0 0 5.34E+08 3.24E+08 - - - 4.2266 0.9993 221125_WJC_METTL3_EV_vs_WT_F08.17928.17928.4 8.93E-07 19/126 K.TK[136.11]EQVTNVGGAVVTGVTAVAQK[136.11].T "sp|P37840|SYUA_HUMAN,tr|A0A669KB41|A0A669KB41_HUMAN,tr|A0A669KBH5|A0A669KBH5_HUMAN,tr|H6UYS7|H6UYS7_HUMAN,tr|E7EPV7|E7EPV7_HUMAN" 5 2172.2085 1.65 120468 17928 4 2172.205159 544.0594 Alpha-synuclein OS=Homo sapiens OX=9606 GN=SNCA PE=1 SV=1 8.26 3033.5 - 806704 - - - -1.5367 - 3.541 0.381 - 253.8 1 2 1 -0.0033 22 0 0 0 5.34E+08 3.24E+08 - - - 2.955 1 221125_WJC_METTL3_EV_vs_WT_F08.17942.17942.3 3.86E-15 29/64 K.HSQAVEELAEQLEQTK[136.11]R[166.11].V sp|P35579|MYH9_HUMAN 1 2013.0246 0.99 120477 17942 3 2013.018536 672.0155 Myosin-9 OS=Homo sapiens OX=9606 GN=MYH9 PE=1 SV=4 4.91 3035.3 - 1.16E+06 - - - -3.0134 - 5.328 0.684 - 1849.3 1 2 0 -0.0061 17 0 0 0 2.48E+08 2.51E+08 - - - 10.3907 0.9784 221125_WJC_METTL3_EV_vs_WT_F08.17945.17945.3 6.26E-05 Dec-56 N.GDK[136.11]EIGNIISDAMK[136.11]K[136.11].V "sp|P10809|CH60_HUMAN,tr|A0A7I2V599|A0A7I2V599_HUMAN,tr|E7EXB4|E7EXB4_HUMAN,tr|A0A7I2YQ71|A0A7I2YQ71_HUMAN,tr|E7ESH4|E7ESH4_HUMAN,tr|A0A7I2V5M1|A0A7I2V5M1_HUMAN,tr|A0A7I2V5K3|A0A7I2V5K3_HUMAN,tr|A0A7I2V369|A0A7I2V369_HUMAN" 8 1641.8822 0.04 120478 17945 3 1641.880686 548.3013 "60 kDa heat shock protein, mitochondrial OS=Homo sapiens OX=9606 GN=HSPD1 PE=1 SV=2" 6.12 3035.7 - 245637 - - - -0.9264 - 2.631 0.443 - 154.3 1 1 1 -0.0015 15 0 0 0 6.33E+05 1.50E+07 - - - 6.0028 0.9997 221125_WJC_METTL3_EV_vs_WT_F08.17947.17947.3 1.56E-05 Nov-48 K.LKDLFDYSPPLHK.N "sp|Q9NYF8|BCLF1_HUMAN,tr|E9PKI6|E9PKI6_HUMAN,tr|A0A1W2PQ43|A0A1W2PQ43_HUMAN,tr|E9PK91|E9PK91_HUMAN,tr|E9PK09|E9PK09_HUMAN,tr|E9PQN2|E9PQN2_HUMAN" 6 1571.8348 2.66 120480 17947 3 1571.833009 524.9522 Bcl-2-associated transcription factor 1 OS=Homo sapiens OX=9606 GN=BCLAF1 PE=1 SV=2 6.75 3035.9 - 418896 - - - -1.1267 - 2.213 0.459 - 147.2 1 2 1 -0.0018 13 0 0 0 2.37E+07 8.91E+06 - - - 5.8106 1 221125_WJC_METTL3_EV_vs_WT_F08.17950.17950.4 7.09E-14 27/96 K.HSQAVEELAEQLEQTK[136.11]R[166.11].V sp|P35579|MYH9_HUMAN 1 2013.0246 1.04 120481 17950 4 2013.019993 504.2634 Myosin-9 OS=Homo sapiens OX=9606 GN=MYH9 PE=1 SV=4 4.91 3036.3 - 1.08E+06 - - - -2.2896 - 4.525 0.651 - 815.3 1 2 0 -0.0046 17 0 0 0 1.58E+08 1.51E+08 - - - 5.4152 1 221125_WJC_METTL3_EV_vs_WT_F08.17965.17965.4 9.97E-10 24/96 K.HSQAVEELAEQLEQTKR.V sp|P35579|MYH9_HUMAN 1 1995.0021 1.04 120490 17965 4 1995.001239 499.7578 Myosin-9 OS=Homo sapiens OX=9606 GN=MYH9 PE=1 SV=4 4.91 3038.3 - 1.07E+06 - - - -0.4476 - 4.241 0.569 - 641.3 1 2 0 -0.0009 17 0 0 0 1.58E+08 1.51E+08 - - - 4.68 0.985 221125_WJC_METTL3_EV_vs_WT_F08.17966.17966.4 5.20E-07 15/84 N.GDKEIGNIISDAMKK.V "sp|P10809|CH60_HUMAN,tr|A0A7I2V599|A0A7I2V599_HUMAN,tr|E7EXB4|E7EXB4_HUMAN,tr|A0A7I2YQ71|A0A7I2YQ71_HUMAN,tr|E7ESH4|E7ESH4_HUMAN,tr|A0A7I2V5M1|A0A7I2V5M1_HUMAN,tr|A0A7I2V5K3|A0A7I2V5K3_HUMAN,tr|A0A7I2V369|A0A7I2V369_HUMAN" 8 1617.8396 1.36 120491 17966 4 1617.837913 405.4672 "60 kDa heat shock protein, mitochondrial OS=Homo sapiens OX=9606 GN=HSPD1 PE=1 SV=2" 6.12 3038.4 - 323772 - - - -1.0471 - 2.809 0.505 - 205.8 1 1 1 -0.0017 15 0 0 0 1.03E+07 7.53E+06 - - - 3.9906 1 221125_WJC_METTL3_EV_vs_WT_F08.17972.17972.4 4.30E-17 34/234 M.PVVLTSGTGSQAQPQPAANQALAAGTHSSPVPGSIGVAGR.S "sp|Q14671|PUM1_HUMAN,tr|Q5T1Z8|Q5T1Z8_HUMAN,tr|E9PM68|E9PM68_HUMAN,tr|E9PMX1|E9PMX1_HUMAN,tr|H0YEH2|H0YEH2_HUMAN,tr|Q5T1Z4|Q5T1Z4_HUMAN,tr|E9PL65|E9PL65_HUMAN,tr|E9PR38|E9PR38_HUMAN" 8 3735.9292 3.25 120494 17972 4 3735.928015 934.9896 Pumilio homolog 1 OS=Homo sapiens OX=9606 GN=PUM1 PE=1 SV=3 10.18 3039.3 - 728117 - - - -0.3303 - 5.186 0.71 - 296.3 1 1 0 -0.0012 40 0 0 0 1.03E+09 3.17E+08 - - - 5.8806 0.9424 221125_WJC_METTL3_EV_vs_WT_F08.17977.17977.4 0.00059 Dec-84 N.GDK[136.11]EIGNIISDAMK[136.11]K[136.11].V "sp|P10809|CH60_HUMAN,tr|A0A7I2V599|A0A7I2V599_HUMAN,tr|E7EXB4|E7EXB4_HUMAN,tr|A0A7I2YQ71|A0A7I2YQ71_HUMAN,tr|E7ESH4|E7ESH4_HUMAN,tr|A0A7I2V5M1|A0A7I2V5M1_HUMAN,tr|A0A7I2V5K3|A0A7I2V5K3_HUMAN,tr|A0A7I2V369|A0A7I2V369_HUMAN" 8 1641.8822 1.38 120497 17977 4 1641.879929 411.4778 "60 kDa heat shock protein, mitochondrial OS=Homo sapiens OX=9606 GN=HSPD1 PE=1 SV=2" 6.12 3039.9 - 263577 - - - -1.3874 - 2.091 0.409 - 115.4 1 1 1 -0.0023 15 0 0 0 1.04E+07 7.53E+06 - - - 3.0492 1 221125_WJC_METTL3_EV_vs_WT_F08.17980.17980.2 2.99E-13 25/42 K.TKEQVTNVGGAVVTGVTAVAQK.T "sp|P37840|SYUA_HUMAN,tr|A0A669KB41|A0A669KB41_HUMAN,tr|A0A669KBH5|A0A669KBH5_HUMAN,tr|H6UYS7|H6UYS7_HUMAN,tr|E7EPV7|E7EPV7_HUMAN" 5 2156.1801 2 120499 17980 2 2156.182732 1079.0973 Alpha-synuclein OS=Homo sapiens OX=9606 GN=SNCA PE=1 SV=1 8.26 3040.3 - 879897 - - - 1.2221 - 4.968 0.73 - 1792.1 1 2 1 0.0026 22 0 0 0 4.51E+07 2.25E+07 - - - 8.373 0.9718 221125_WJC_METTL3_EV_vs_WT_F08.17981.17981.3 0.0718 Aug-48 K.LK[136.11]DLFDYSPPLHK[136.11].N "sp|Q9NYF8|BCLF1_HUMAN,tr|E9PKI6|E9PKI6_HUMAN,tr|A0A1W2PQ43|A0A1W2PQ43_HUMAN,tr|E9PK91|E9PK91_HUMAN,tr|E9PK09|E9PK09_HUMAN,tr|E9PQN2|E9PQN2_HUMAN" 6 1587.8632 2.73 120500 17981 3 1587.85895 530.295 Bcl-2-associated transcription factor 1 OS=Homo sapiens OX=9606 GN=BCLAF1 PE=1 SV=2 6.75 3040.4 - 284463 - - - -2.664 - 1.782 0.24 - 59.9 1 2 1 -0.0042 13 0 0 0 2.41E+07 8.82E+06 - - - 2.781 1 221125_WJC_METTL3_EV_vs_WT_F08.17987.17987.4 1.32E-11 31/162 Q.VIILNHPGQISAGYAPVLDC[160.03]HTAHIAC[160.03]K[136.11].F "sp|P68104|EF1A1_HUMAN,tr|A0A7I2V659|A0A7I2V659_HUMAN,tr|A0A7I2V5N4|A0A7I2V5N4_HUMAN,tr|A0A087WVQ9|A0A087WVQ9_HUMAN,tr|A0A087WV01|A0A087WV01_HUMAN" 5 3062.5674 0.32 120504 17987 4 3062.5661 766.6491 Elongation factor 1-alpha 1 OS=Homo sapiens OX=9606 GN=EEF1A1 PE=1 SV=1 6.98 3041.1 - 3.74E+06 - - - -0.4134 - 5.412 0.66 - 585.1 1 1 0 -0.0013 28 0 0 0 2.80E+07 8.85E+07 - - - 5.4946 0.9999 221125_WJC_METTL3_EV_vs_WT_F08.17991.17991.4 2.05E-07 19/120 R.DSFDDR[166.11]GPSLNPVLDYDHGSR[166.11].S "sp|P43243|MATR3_HUMAN,tr|A8MXP9|A8MXP9_HUMAN,tr|D6R991|D6R991_HUMAN,tr|A0A0R4J2E8|A0A0R4J2E8_HUMAN,tr|D6REM6|D6REM6_HUMAN" 5 2381.0787 1.36 120506 17991 4 2381.080012 596.277 Matrin-3 OS=Homo sapiens OX=9606 GN=MATR3 PE=1 SV=2 4.28 3041.6 - 652516 - - - 0.5485 - 3.215 0.562 - 261.2 1 2 1 0.0013 21 0 0 0 7.37E+07 5.41E+07 - - - 4.5034 1 221125_WJC_METTL3_EV_vs_WT_F08.18011.18011.4 1.67E-16 41/234 M.PVVLTSGTGSQAQPQPAANQALAAGTHSSPVPGSIGVAGR[166.11].S "sp|Q14671|PUM1_HUMAN,tr|Q5T1Z8|Q5T1Z8_HUMAN,tr|E9PM68|E9PM68_HUMAN,tr|E9PMX1|E9PMX1_HUMAN,tr|H0YEH2|H0YEH2_HUMAN,tr|Q5T1Z4|Q5T1Z4_HUMAN,tr|E9PL65|E9PL65_HUMAN,tr|E9PR38|E9PR38_HUMAN" 8 3745.9375 3.25 120517 18011 4 3745.932741 937.4917 Pumilio homolog 1 OS=Homo sapiens OX=9606 GN=PUM1 PE=1 SV=3 10.18 3044.2 - 1.95E+06 - - - -1.2755 - 6.047 0.685 - 603.5 1 1 0 -0.0048 40 0 0 0 1.03E+09 3.17E+08 - - - 5.7064 0.9999 221125_WJC_METTL3_EV_vs_WT_F08.18013.18013.4 6.23E-07 20/120 R.DSFDDRGPSLNPVLDYDHGSR.S "sp|P43243|MATR3_HUMAN,tr|A8MXP9|A8MXP9_HUMAN,tr|D6R991|D6R991_HUMAN,tr|A0A0R4J2E8|A0A0R4J2E8_HUMAN,tr|D6REM6|D6REM6_HUMAN" 5 2361.0622 1.36 120519 18013 4 2361.05872 591.2728 Matrin-3 OS=Homo sapiens OX=9606 GN=MATR3 PE=1 SV=2 4.28 3044.5 - 1.07E+06 - - - -1.4595 - 3.431 0.557 - 302.2 1 2 1 -0.0034 21 0 0 0 7.36E+07 5.40E+07 - - - 4.4808 0.999 221125_WJC_METTL3_EV_vs_WT_F08.18017.18017.4 0.068 14/90 K.YFLHDDR[166.11]DDGVDYWAK[136.11].R "sp|Q9NYF8|BCLF1_HUMAN,tr|H0YF14|H0YF14_HUMAN" 2 2031.9082 2.33 120520 18017 4 2031.904063 508.9843 Bcl-2-associated transcription factor 1 OS=Homo sapiens OX=9606 GN=BCLAF1 PE=1 SV=2 4.28 3045 - 1.01E+06 - - - -2.0242 - 2.547 0.383 - 142.5 1 2 1 -0.0041 16 0 0 0 5.38E+07 2.31E+07 - - - 2.8878 0.9997 221125_WJC_METTL3_EV_vs_WT_F08.18025.18025.3 0.000134 Dec-68 K.HQSSNLNVPELNSINMSR[166.11].S sp|Q96S59|RANB9_HUMAN 1 2048.9937 1.03 120526 18025 3 2048.986542 684.0052 Ran-binding protein 9 OS=Homo sapiens OX=9606 GN=RANBP9 PE=1 SV=1 6.75 3046.1 - 375047 - - - -3.4964 - 2.902 0.411 - 171.5 1 2 0 -0.0072 18 0 0 0 9.36E+06 9.10E+06 - - - 5.7732 1 221125_WJC_METTL3_EV_vs_WT_F08.18029.18029.4 1.30E-09 21/120 R.SSDKFC[160.03]SPISSELAQNHEFYK.N "sp|Q8IVH2|FOXP4_HUMAN,tr|B7ZBM3|B7ZBM3_HUMAN" 2 2473.122 5.73 120528 18029 4 2473.121746 619.2878 Forkhead box protein P4 OS=Homo sapiens OX=9606 GN=FOXP4 PE=1 SV=1 5.42 3046.6 - 527917 - - - -0.0987 - 3.777 0.646 - 271.4 1 2 1 -0.0002 21 0 0 0 2.63E+07 4.60E+06 - - - 5.2881 0.9959 221125_WJC_METTL3_EV_vs_WT_F08.18031.18031.4 0.0537 13/90 K.YFLHDDRDDGVDYWAK.R "sp|Q9NYF8|BCLF1_HUMAN,tr|H0YF14|H0YF14_HUMAN" 2 2013.8857 2.33 120529 18031 4 2013.887127 504.4787 Bcl-2-associated transcription factor 1 OS=Homo sapiens OX=9606 GN=BCLAF1 PE=1 SV=2 4.28 3046.8 - 2.73E+06 - - - 0.7056 - 1.797 0.3 - 91.6 1 2 1 0.0014 16 0 0 0 5.39E+07 2.31E+07 - - - 2.0433 1 221125_WJC_METTL3_EV_vs_WT_F08.18032.18032.3 5.60E-19 36/156 M.PVVLTSGTGSQAQPQPAANQALAAGTHSSPVPGSIGVAGR.S "sp|Q14671|PUM1_HUMAN,tr|Q5T1Z8|Q5T1Z8_HUMAN,tr|E9PM68|E9PM68_HUMAN,tr|E9PMX1|E9PMX1_HUMAN,tr|H0YEH2|H0YEH2_HUMAN,tr|Q5T1Z4|Q5T1Z4_HUMAN,tr|E9PL65|E9PL65_HUMAN,tr|E9PR38|E9PR38_HUMAN" 8 3735.9292 4.09 120530 18032 3 3735.929899 1246.317 Pumilio homolog 1 OS=Homo sapiens OX=9606 GN=PUM1 PE=1 SV=3 10.18 3046.9 - 1.52E+06 - - - 0.174 - 5.283 0.747 - 625 1 1 0 0.0006 40 0 0 0 1.55E+08 3.79E+07 - - - 10.6975 1 221125_WJC_METTL3_EV_vs_WT_F08.18036.18036.3 5.99E-15 30/156 M.PVVLTSGTGSQAQPQPAANQALAAGTHSSPVPGSIGVAGR[166.11].S "sp|Q14671|PUM1_HUMAN,tr|Q5T1Z8|Q5T1Z8_HUMAN,tr|E9PM68|E9PM68_HUMAN,tr|E9PMX1|E9PMX1_HUMAN,tr|H0YEH2|H0YEH2_HUMAN,tr|Q5T1Z4|Q5T1Z4_HUMAN,tr|E9PL65|E9PL65_HUMAN,tr|E9PR38|E9PR38_HUMAN" 8 3745.9375 4.09 120532 18036 3 3745.929446 1249.6531 Pumilio homolog 1 OS=Homo sapiens OX=9606 GN=PUM1 PE=1 SV=3 10.18 3047.5 - 528282 - - - -2.1551 - 5.062 0.726 - 490.1 1 1 0 -0.0081 40 0 0 0 1.55E+08 3.79E+07 - - - 10.363 0.9999 221125_WJC_METTL3_EV_vs_WT_F08.18043.18043.4 1.54E-07 19/150 R.TLVNK[136.11]EEPPK[136.11]ELPAAEPVLSPLEGTK[136.11].M "sp|Q9BY77|PDIP3_HUMAN,tr|F6VRR5|F6VRR5_HUMAN" 2 2809.5539 1.7 120536 18043 4 2809.551262 703.3958 Polymerase delta-interacting protein 3 OS=Homo sapiens OX=9606 GN=POLDIP3 PE=1 SV=2 4.65 3048.4 - 873592 - - - -0.9485 - 3.665 0.562 - 203.4 1 2 2 -0.0027 26 0 0 0 1.22E+08 7.19E+07 - - - 4.5266 1 221125_WJC_METTL3_EV_vs_WT_F08.18051.18051.3 2.86E-09 22/72 R.SDKNNEFIVIHNGIITNYK.D "sp|Q06210|GFPT1_HUMAN,tr|A0A6I8PRN4|A0A6I8PRN4_HUMAN,tr|A0A6I8PTT9|A0A6I8PTT9_HUMAN" 3 2218.1382 1.85 120542 18051 3 2218.140978 740.3867 Glutamine--fructose-6-phosphate aminotransferase [isomerizing] 1 OS=Homo sapiens OX=9606 GN=GFPT1 PE=1 SV=3 6.47 3049.4 - 944327 - - - 1.238 - 4.391 0.626 - 666.6 1 2 1 0.0027 19 0 0 0 6.33E+07 3.43E+07 - - - 9.1535 1 221125_WJC_METTL3_EV_vs_WT_F08.18053.18053.3 1.51E-19 25/84 K.HTQENC[160.03]ETWGVNGETGTLVDMK[136.11].E "sp|P49368|TCPG_HUMAN,tr|B4DUR8|B4DUR8_HUMAN" 2 2513.1042 0.23 120544 18053 3 2513.103103 838.7087 T-complex protein 1 subunit gamma OS=Homo sapiens OX=9606 GN=CCT3 PE=1 SV=4 4.4 3049.6 - 4.07E+06 - - - -0.4516 - 4.695 0.782 - 1133 1 2 0 -0.0011 22 0 0 0 7.13E+07 3.11E+08 - - - 10.9247 0.9999 221125_WJC_METTL3_EV_vs_WT_F08.18054.18054.4 9.04E-10 20/108 R.SDKNNEFIVIHNGIITNYK.D "sp|Q06210|GFPT1_HUMAN,tr|A0A6I8PRN4|A0A6I8PRN4_HUMAN,tr|A0A6I8PTT9|A0A6I8PTT9_HUMAN" 3 2218.1382 1.39 120545 18054 4 2218.139179 555.5418 Glutamine--fructose-6-phosphate aminotransferase [isomerizing] 1 OS=Homo sapiens OX=9606 GN=GFPT1 PE=1 SV=3 6.47 3049.6 - 1.93E+06 - - - 0.4269 - 3.841 0.581 - 330.2 1 2 1 0.0009 19 0 0 0 8.67E+07 6.21E+07 - - - 4.738 0.9995 221125_WJC_METTL3_EV_vs_WT_F08.18055.18055.4 1.80E-07 19/108 R.SDK[136.11]NNEFIVIHNGIITNYK[136.11].D "sp|Q06210|GFPT1_HUMAN,tr|A0A6I8PRN4|A0A6I8PRN4_HUMAN,tr|A0A6I8PTT9|A0A6I8PTT9_HUMAN" 3 2234.1666 1.39 120546 18055 4 2234.176593 559.5489 Glutamine--fructose-6-phosphate aminotransferase [isomerizing] 1 OS=Homo sapiens OX=9606 GN=GFPT1 PE=1 SV=3 6.47 3049.7 - 1.48E+06 - - - 4.4585 - 3.66 0.587 - 360 1 2 1 0.01 19 0 0 0 8.67E+07 6.21E+07 - - - 4.7714 0.9934 221125_WJC_METTL3_EV_vs_WT_F08.18058.18058.4 5.24E-12 28/144 A.LQSHSSPEGKEEPEPLSPELEYIPR.K sp|Q8N490|PNKD_HUMAN 1 2847.3927 1.02 120547 18058 4 2847.395892 712.8554 Probable hydrolase PNKD OS=Homo sapiens OX=9606 GN=PNKD PE=1 SV=2 4.47 3050.1 - 1.09E+06 - - - 1.1319 - 4.208 0.597 - 656.5 1 1 1 0.0032 25 0 0 0 2.75E+07 2.69E+07 - - - 4.8785 1 221125_WJC_METTL3_EV_vs_WT_F08.18060.18060.3 2.37E-05 31/64 K.HSQAVEELAEQLEQTKR.V sp|P35579|MYH9_HUMAN 1 1995.0021 0.99 120549 18060 3 1995.002175 666.008 Myosin-9 OS=Homo sapiens OX=9606 GN=MYH9 PE=1 SV=4 4.91 3050.3 - 5.85E+06 - - - 0.0216 - 5.872 0.682 - 1887.3 1 2 0 0 17 0 0 0 2.48E+08 2.51E+08 - - - 10.6157 0.9861 221125_WJC_METTL3_EV_vs_WT_F08.18061.18061.2 1.16E-05 13/32 P.STASAVPELATDPELEK[136.11].K "sp|Q86U44|MTA70_HUMAN,tr|B4E349|B4E349_HUMAN,tr|F5H6D8|F5H6D8_HUMAN,tr|H0YFV6|H0YFV6_HUMAN,tr|B4DTN4|B4DTN4_HUMAN" 5 1764.8873 0.02 120550 18061 2 1764.885358 883.4509 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 4 3050.4 - 825193 - - - -1.0862 - 2.038 0.456 - 277.2 1 1 0 -0.0019 17 0 0 0 1.09E+06 5.14E+07 - - - 4.1588 0.9995 221125_WJC_METTL3_EV_vs_WT_F08.18063.18063.3 0.000129 Dec-60 K.YFLHDDR[166.11]DDGVDYWAK[136.11].R "sp|Q9NYF8|BCLF1_HUMAN,tr|H0YF14|H0YF14_HUMAN" 2 2031.9082 3.46 120552 18063 3 2031.90528 678.31 Bcl-2-associated transcription factor 1 OS=Homo sapiens OX=9606 GN=BCLAF1 PE=1 SV=2 4.28 3050.7 - 531091 - - - -1.4253 - 2.126 0.44 - 146.6 1 2 1 -0.0029 16 0 0 0 6.96E+07 2.01E+07 - - - 5.38 0.9855 221125_WJC_METTL3_EV_vs_WT_F08.18064.18064.4 0.12 7/108 K.QEQAHDDAIWSVAWGTNKK.E "sp|Q9GZS3|WDR61_HUMAN,tr|H0YM76|H0YM76_HUMAN,tr|H0YMF9|H0YMF9_HUMAN,tr|H0YN81|H0YN81_HUMAN" 4 2183.0396 0.82 120553 18064 4 2183.043008 546.7672 WD repeat-containing protein 61 OS=Homo sapiens OX=9606 GN=WDR61 PE=1 SV=1 5.38 3050.8 - 252039 - - - 1.5698 - 1.717 0.195 - 17.7 1 2 0 0.0034 19 0 0 0 5.83E+06 7.07E+06 - - - 1.1052 1 221125_WJC_METTL3_EV_vs_WT_F08.18068.18068.4 1.18E-11 28/180 K.AFQYVETHGEVC[160.03]PANWTPDSPTIK[136.11]PSPAASK[136.11].E sp|P30048|PRDX3_HUMAN 1 3400.6369 0.63 120555 18068 4 3400.636186 851.1665 "Thioredoxin-dependent peroxide reductase, mitochondrial OS=Homo sapiens OX=9606 GN=PRDX3 PE=1 SV=3" 5.45 3051.3 - 834970 - - - -0.2076 - 4.076 0.718 - 301.4 1 2 0 -0.0007 31 0 0 0 1.01E+07 1.61E+07 - - - 5.9023 0.9999 221125_WJC_METTL3_EV_vs_WT_F08.18071.18071.3 4.99E-06 15/48 R.GYFEYIEENKYSR.A "sp|Q00839|HNRPU_HUMAN,tr|Q5RI18|Q5RI18_HUMAN,tr|A0A1W2PP35|A0A1W2PP35_HUMAN,tr|A0A1W2PPS1|A0A1W2PPS1_HUMAN,tr|A0A1W2PRI6|A0A1W2PRI6_HUMAN" 5 1696.7733 0.95 120556 18071 3 1696.776205 566.5984 Heterogeneous nuclear ribonucleoprotein U OS=Homo sapiens OX=9606 GN=HNRNPU PE=1 SV=6 4.79 3051.7 - 306604 - - - 1.7109 - 2.919 0.578 - 250.5 1 2 1 0.0029 13 0 0 0 1.49E+07 1.57E+07 - - - 7.8878 0.9999 221125_WJC_METTL3_EV_vs_WT_F08.18077.18077.4 3.55E-05 16/96 R.EKDRDPEAQFEMPYVVR.L "sp|O14744|ANM5_HUMAN,tr|H0YJD3|H0YJD3_HUMAN,tr|H7BZ44|H7BZ44_HUMAN" 3 2107.9997 3.29 120560 18077 4 2108.002802 528.0072 Protein arginine N-methyltransferase 5 OS=Homo sapiens OX=9606 GN=PRMT5 PE=1 SV=4 4.51 3052.4 - 388310 - - - 1.4763 - 2.94 0.548 - 186.7 1 2 2 0.0031 17 0 0 0 1.12E+08 3.39E+07 - - - 4.3694 1 221125_WJC_METTL3_EV_vs_WT_F08.18078.18078.3 7.63E-17 24/144 L.SVPQLSGAGGGGGEAGAGGGAAAVAAGGVVTTTASGK.R "sp|P56270|MAZ_HUMAN,tr|A0A087WWR2|A0A087WWR2_HUMAN" 2 2954.4694 0.33 120561 18078 3 2954.465137 985.8304 Myc-associated zinc finger protein OS=Homo sapiens OX=9606 GN=MAZ PE=1 SV=1 5.72 3052.6 - 365486 - - - -1.428 - 4.881 0.729 - 363 1 1 0 -0.0042 37 0 0 0 3.63E+06 1.10E+07 - - - 10.3138 1 221125_WJC_METTL3_EV_vs_WT_F08.18081.18081.3 3.29E-14 24/84 K.HTQENC[160.03]ETWGVNGETGTLVDMK.E "sp|P49368|TCPG_HUMAN,tr|B4DUR8|B4DUR8_HUMAN" 2 2505.09 0.23 120562 18081 3 2505.083146 836.0373 T-complex protein 1 subunit gamma OS=Homo sapiens OX=9606 GN=CCT3 PE=1 SV=4 4.4 3053 - 2.76E+06 - - - -2.7512 - 4.486 0.76 - 903.5 1 2 0 -0.0069 22 0 0 0 7.13E+07 3.11E+08 - - - 10.5699 1 221125_WJC_METTL3_EV_vs_WT_F08.18082.18082.3 1.30E-15 26/96 K.YTHLVDQDTTSFDSAWGQESAQNTK.F sp|P55081|MFAP1_HUMAN 1 2828.2525 1.5 120563 18082 3 2828.249213 943.7581 Microfibrillar-associated protein 1 OS=Homo sapiens OX=9606 GN=MFAP1 PE=1 SV=2 4.22 3053.1 - 2.73E+06 - - - -1.1785 - 4.568 0.704 - 605.2 1 2 0 -0.0033 25 0 0 0 5.20E+07 3.46E+07 - - - 9.8828 0.9999 221125_WJC_METTL3_EV_vs_WT_F08.18093.18093.4 9.18E-09 24/138 K.ISTDKETNEGVLSVVKPLNYEENR.Q sp|Q14574|DSC3_HUMAN 1 2733.3821 186.84 120570 18093 4 2733.379638 684.3528 Desmocollin-3 OS=Homo sapiens OX=9606 GN=DSC3 PE=1 SV=3 4.59 3054.6 - 2.93E+06 - - - -0.9022 - 4.185 0.615 - 288.1 1 2 1 -0.0025 24 0 0 0 1.22E+08 6.54E+05 - - - 5.0377 0.9997 221125_WJC_METTL3_EV_vs_WT_F08.18094.18094.4 1.83E-05 14/108 K.QEQAHDDAIWSVAWGTNK[136.11]K[136.11].E "sp|Q9GZS3|WDR61_HUMAN,tr|H0YM76|H0YM76_HUMAN,tr|H0YMF9|H0YMF9_HUMAN,tr|H0YN81|H0YN81_HUMAN" 4 2199.068 0.82 120571 18094 4 2199.059194 550.7743 WD repeat-containing protein 61 OS=Homo sapiens OX=9606 GN=WDR61 PE=1 SV=1 5.38 3054.7 - 514223 - - - -3.9958 - 2.124 0.479 - 91.3 1 2 0 -0.0088 19 0 0 0 5.75E+06 7.00E+06 - - - 3.6476 1 221125_WJC_METTL3_EV_vs_WT_F08.18095.18095.4 3.44E-10 23/144 A.LQSHSSPEGK[136.11]EEPEPLSPELEYIPR[166.11].K sp|Q8N490|PNKD_HUMAN 1 2865.4151 1.5 120572 18095 4 2865.413096 717.3611 Probable hydrolase PNKD OS=Homo sapiens OX=9606 GN=PNKD PE=1 SV=2 4.47 3054.8 - 1.43E+06 - - - -0.713 - 3.811 0.673 - 365.9 1 1 1 -0.002 25 0 0 0 4.91E+07 3.26E+07 - - - 5.5088 0.9999 221125_WJC_METTL3_EV_vs_WT_F08.18098.18098.3 3.22E-07 14/48 R.GYFEYIEENK[136.11]YSR[166.11].A "sp|Q00839|HNRPU_HUMAN,tr|Q5RI18|Q5RI18_HUMAN,tr|A0A1W2PP35|A0A1W2PP35_HUMAN,tr|A0A1W2PPS1|A0A1W2PPS1_HUMAN,tr|A0A1W2PRI6|A0A1W2PRI6_HUMAN" 5 1714.7958 0.95 120573 18098 3 1714.793457 572.6059 Heterogeneous nuclear ribonucleoprotein U OS=Homo sapiens OX=9606 GN=HNRNPU PE=1 SV=6 4.79 3055.2 - 719010 - - - -1.35 - 2.697 0.583 - 213.9 1 2 1 -0.0023 13 0 0 0 1.49E+07 1.57E+07 - - - 7.7292 0.9997 221125_WJC_METTL3_EV_vs_WT_F08.18109.18109.3 1.27E-10 30/92 K.ISTDKETNEGVLSVVKPLNYEENR.Q sp|Q14574|DSC3_HUMAN 1 2733.3821 999 120577 18109 3 2733.372217 912.1346 Desmocollin-3 OS=Homo sapiens OX=9606 GN=DSC3 PE=1 SV=3 4.59 3056.7 - 944223 - - - -3.6171 - 3.898 0.569 - 540.1 1 2 1 -0.0099 24 0 0 0 1.94E+07 0.00E+00 - - - 8.0409 0.9997 221125_WJC_METTL3_EV_vs_WT_F08.18130.18130.3 6.20E-09 22/64 R.EKDRDPEAQFEMPYVVR.L "sp|O14744|ANM5_HUMAN,tr|H0YJD3|H0YJD3_HUMAN,tr|H7BZ44|H7BZ44_HUMAN" 3 2107.9997 4.26 120580 18130 3 2107.995636 703.6738 Protein arginine N-methyltransferase 5 OS=Homo sapiens OX=9606 GN=PRMT5 PE=1 SV=4 4.51 3060 - 2.61E+06 - - - -1.9232 - 4.093 0.387 - 560.8 1 2 2 -0.0041 17 0 0 0 6.45E+07 1.51E+07 - - - 6.4138 1 221125_WJC_METTL3_EV_vs_WT_F08.18173.18173.3 2.62E-08 24/72 R.HPHDIIDDINSGAVEC[160.03]PAS.- sp|P30050|RL12_HUMAN 1 2045.9113 - 120584 18173 3 2045.903862 682.9777 60S ribosomal protein L12 OS=Homo sapiens OX=9606 GN=RPL12 PE=1 SV=1 4.21 3066.9 - 5.12E+06 - - - -3.6204 - 3.957 0.611 - 911.3 1 2 0 -0.0074 19 0 0 0 - - - - - 8.7293 1 221125_WJC_METTL3_EV_vs_WT_F08.18183.18183.2 1.14E-08 18/36 R.HPHDIIDDINSGAVEC[160.03]PAS.- sp|P30050|RL12_HUMAN 1 2045.9113 - 120585 18183 2 2045.904716 1023.9629 60S ribosomal protein L12 OS=Homo sapiens OX=9606 GN=RPL12 PE=1 SV=1 4.21 3068.5 - 6.09E+06 - - - -3.203 - 2.99 0.624 - 582.4 1 2 0 -0.0066 19 0 0 0 - - - - - 6.3406 1 221125_WJC_METTL3_EV_vs_WT_F08.18213.18213.2 2.96E-07 15/20 V.PELATDPELEK[136.11].K "sp|Q86U44|MTA70_HUMAN,tr|B4E349|B4E349_HUMAN,tr|F5H6D8|F5H6D8_HUMAN,tr|H0YFV6|H0YFV6_HUMAN,tr|B4DTN4|B4DTN4_HUMAN" 5 1248.6329 0.07 120588 18213 2 1248.62547 625.3237 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 4 3073.3 - 1.85E+06 - - - -5.9489 - 2.763 0.578 - 648.3 1 1 0 -0.0074 11 0 0 0 1.51E+07 2.19E+08 - - - 6.0572 0.9998 221125_WJC_METTL3_EV_vs_WT_F08.18241.18241.4 3.24E-09 19/120 R.DSFDDR[166.11]GPSLNPVLDYDHGSR[166.11].S "sp|P43243|MATR3_HUMAN,tr|A8MXP9|A8MXP9_HUMAN,tr|D6R991|D6R991_HUMAN,tr|A0A0R4J2E8|A0A0R4J2E8_HUMAN,tr|D6REM6|D6REM6_HUMAN" 5 2381.0787 1.35 120592 18241 4 2381.071171 596.277 Matrin-3 OS=Homo sapiens OX=9606 GN=MATR3 PE=1 SV=2 4.28 3077.6 - 5.57E+06 - - - -3.1645 - 3.605 0.601 - 263.6 1 2 1 -0.0075 21 0 0 0 3.47E+09 2.57E+09 - - - 4.879 0.9996 221125_WJC_METTL3_EV_vs_WT_F08.18242.18242.4 1.14E-09 22/120 R.DSFDDRGPSLNPVLDYDHGSR.S "sp|P43243|MATR3_HUMAN,tr|A8MXP9|A8MXP9_HUMAN,tr|D6R991|D6R991_HUMAN,tr|A0A0R4J2E8|A0A0R4J2E8_HUMAN,tr|D6REM6|D6REM6_HUMAN" 5 2361.0622 1.35 120593 18242 4 2361.052134 591.2728 Matrin-3 OS=Homo sapiens OX=9606 GN=MATR3 PE=1 SV=2 4.28 3077.6 - 6.09E+06 - - - -4.2489 - 3.726 0.617 - 373.5 1 2 1 -0.01 21 0 0 0 3.47E+09 2.58E+09 - - - 5.0285 1 221125_WJC_METTL3_EV_vs_WT_F08.18247.18247.3 1.78E-07 31/80 R.DSFDDR[166.11]GPSLNPVLDYDHGSR[166.11].S "sp|P43243|MATR3_HUMAN,tr|A8MXP9|A8MXP9_HUMAN,tr|D6R991|D6R991_HUMAN,tr|A0A0R4J2E8|A0A0R4J2E8_HUMAN,tr|D6REM6|D6REM6_HUMAN" 5 2381.0787 1.35 120594 18247 3 2381.073582 794.7002 Matrin-3 OS=Homo sapiens OX=9606 GN=MATR3 PE=1 SV=2 4.28 3078.4 - 2.48E+06 - - - -2.152 - 4.367 0.638 - 932.1 1 2 1 -0.0051 21 0 0 0 9.98E+08 7.39E+08 - - - 9.1857 1 221125_WJC_METTL3_EV_vs_WT_F08.18249.18249.3 2.12E-13 26/80 R.DSFDDRGPSLNPVLDYDHGSR.S "sp|P43243|MATR3_HUMAN,tr|A8MXP9|A8MXP9_HUMAN,tr|D6R991|D6R991_HUMAN,tr|A0A0R4J2E8|A0A0R4J2E8_HUMAN,tr|D6REM6|D6REM6_HUMAN" 5 2361.0622 1.35 120595 18249 3 2361.055106 788.028 Matrin-3 OS=Homo sapiens OX=9606 GN=MATR3 PE=1 SV=2 4.28 3078.6 - 3.97E+06 - - - -2.9902 - 4.149 0.609 - 734 1 2 1 -0.0071 21 0 0 0 9.99E+08 7.39E+08 - - - 8.7391 1 221125_WJC_METTL3_EV_vs_WT_F08.18259.18259.2 4.74E-11 29/64 R.SDSPVPTAPTSGGPK[136.11]PSTASAVPELATDPELEK[136.11].K "sp|Q86U44|MTA70_HUMAN,tr|B4E349|B4E349_HUMAN,tr|F5H6D8|F5H6D8_HUMAN,tr|B4DTN4|B4DTN4_HUMAN" 4 3248.6271 0.03 120599 18259 2 3250.625447 1625.3208 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 4.18 3079.9 - 3.13E+06 - - - 615.1365 - 4.005 0.705 - 568.3 1 2 0 1.9983 33 0 0 0 1.74E+07 5.87E+08 - - - 7.032 0.8678 221125_WJC_METTL3_EV_vs_WT_F08.18276.18276.3 0.0826 12/116 R.SDSPVPTAPTSGGPK[136.11]PSTASAVPELATDPE.L "sp|Q86U44|MTA70_HUMAN,tr|B4E349|B4E349_HUMAN,tr|F5H6D8|F5H6D8_HUMAN,tr|B4DTN4|B4DTN4_HUMAN" 4 2870.3913 0.08 120605 18276 3 2870.387314 957.8044 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 4.16 3082.1 - 2.12E+06 - - - -1.381 - 1.912 0.283 - 44.7 1 1 0 -0.004 30 0 0 0 5.21E+06 6.26E+07 - - - 3.1852 0.9999 221125_WJC_METTL3_EV_vs_WT_F08.18277.18277.4 6.91E-08 26/120 K.FEK[136.11]DFDFESANAQFNK[136.11]EEIDR[166.11].E "sp|Q8ND56|LS14A_HUMAN,tr|A0A140TA76|A0A140TA76_HUMAN,tr|K7EMZ9|K7EMZ9_HUMAN" 3 2604.1979 1.1 120606 18277 4 2604.190543 652.0567 Protein LSM14 homolog A OS=Homo sapiens OX=9606 GN=LSM14A PE=1 SV=3 4.2 3082.2 - 1.62E+06 - - - -2.8181 - 4.916 0.595 - 818.5 1 2 2 -0.0073 21 0 0 0 4.27E+07 3.88E+07 - - - 4.9294 1 221125_WJC_METTL3_EV_vs_WT_F08.18302.18302.3 7.19E-13 23/104 R.AHSGAAPWQPLAAPSGASAQAAEQLQR.G "sp|P51617|IRAK1_HUMAN,tr|H7C2I6|H7C2I6_HUMAN,tr|H7C3C1|H7C3C1_HUMAN,tr|H7C224|H7C224_HUMAN,tr|D3YTB5|D3YTB5_HUMAN" 5 2670.3263 3.3 120618 18302 3 2670.31825 891.116 Interleukin-1 receptor-associated kinase 1 OS=Homo sapiens OX=9606 GN=IRAK1 PE=1 SV=2 6.79 3085.4 - 1.00E+06 - - - -3 - 4.818 0.701 - 422 1 2 0 -0.008 27 0 0 0 2.95E+07 8.93E+06 - - - 9.9707 1 221125_WJC_METTL3_EV_vs_WT_F08.18315.18315.2 7.19E-09 15/34 K.PSTASAVPELATDPELEK[136.11].K "sp|Q86U44|MTA70_HUMAN,tr|B4E349|B4E349_HUMAN,tr|F5H6D8|F5H6D8_HUMAN,tr|H0YFV6|H0YFV6_HUMAN,tr|B4DTN4|B4DTN4_HUMAN" 5 1861.94 0.001 120626 18315 2 1862.939013 931.9773 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 4 3087 - 382945 - - - 536.5232 - 3.355 0.583 - 393.3 1 1 0 0.999 18 0 0 0 0.00E+00 2.12E+07 - - - 6.0093 0.9989 221125_WJC_METTL3_EV_vs_WT_F08.18317.18317.4 0.0104 Nov-84 R.STSHK[136.11]PDEIYGMIER[166.11].L sp|Q86U44|MTA70_HUMAN 1 1779.8581 0.001 120628 18317 4 1779.854094 445.9718 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 5.42 3087.3 - 496638 - - - -2.2249 - 1.647 0.326 - 74.3 1 2 0 -0.004 15 0 0 0 0.00E+00 1.18E+07 - - - 2.2409 1 221125_WJC_METTL3_EV_vs_WT_F08.18323.18323.4 7.21E-09 15/156 R.SLQTLPTDSSTFDTDTFC[160.03]PPRPKPVAR.K "sp|Q9NQG6|MID51_HUMAN,tr|B0QY95|B0QY95_HUMAN" 2 3033.4866 0.58 120632 18323 4 3033.487789 759.3789 Mitochondrial dynamics protein MID51 OS=Homo sapiens OX=9606 GN=MIEF1 PE=1 SV=1 5.76 3088.1 - 472857 - - - 0.3966 - 3.174 0.593 - 143.2 1 2 0 0.0012 27 0 0 0 8.03E+06 1.39E+07 - - - 4.7485 1 221125_WJC_METTL3_EV_vs_WT_F08.18336.18336.4 2.99E-06 20/108 K.TGSQYDIQDAIDKGLVDRK.F sp|P15924|DESP_HUMAN 1 2121.0702 6.23 120641 18336 4 2121.071481 531.2748 Desmoplakin OS=Homo sapiens OX=9606 GN=DSP PE=1 SV=3 4.58 3089.8 - 517510 - - - 0.5983 - 3.99 0.623 - 423.7 1 2 1 0.0013 19 0 0 0 8.99E+06 1.44E+06 - - - 5.1163 0.9999 221125_WJC_METTL3_EV_vs_WT_F08.18339.18339.3 0.000937 Aug-52 K.K[136.11]GPGEVAGTVTGQK[136.11].R "sp|Q86U44|MTA70_HUMAN,tr|F5H6D8|F5H6D8_HUMAN,tr|H0YFV6|H0YFV6_HUMAN,tr|B4DTN4|B4DTN4_HUMAN" 4 1343.738 0.001 120644 18339 3 1343.736506 448.9199 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 8.59 3090.2 - 198071 - - - -1.0962 - 1.964 0.428 - 88.6 1 2 0 -0.0015 14 0 0 0 0.00E+00 3.47E+06 - - - 5.1052 0.9983 221125_WJC_METTL3_EV_vs_WT_F08.18345.18345.3 2.19E-07 16/68 K.PSTASAVPELATDPELEK[136.11].K "sp|Q86U44|MTA70_HUMAN,tr|B4E349|B4E349_HUMAN,tr|F5H6D8|F5H6D8_HUMAN,tr|H0YFV6|H0YFV6_HUMAN,tr|B4DTN4|B4DTN4_HUMAN" 5 1861.94 0.32 120647 18345 3 1861.939378 621.654 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 4 3090.9 - 575878 - - - -0.355 - 2.916 0.557 - 244.1 1 1 0 -0.0007 18 0 0 0 4.02E+06 1.27E+07 - - - 7.4148 1 221125_WJC_METTL3_EV_vs_WT_F08.18352.18352.4 9.86E-05 20/126 K.R[166.11]PHLSVILVGENPASHSYVLNK[136.11].T "sp|P13995|MTDC_HUMAN,tr|A0A7I2V2U6|A0A7I2V2U6_HUMAN,tr|B8ZZU9|B8ZZU9_HUMAN,tr|B9A062|B9A062_HUMAN" 4 2447.3404 1.24 120652 18352 4 2447.342138 612.8424 "Bifunctional methylenetetrahydrofolate dehydrogenase\cyclohydrolase, mitochondrial OS=Homo sapiens OX=9606 GN=MTHFD2 PE=1 SV=2" 8.6 3091.8 - 588840 - - - 0.711 - 4.084 0.471 - 306.1 1 2 0 0.0017 22 0 0 0 5.39E+07 4.36E+07 - - - 3.7855 0.9999 221125_WJC_METTL3_EV_vs_WT_F08.18354.18354.4 1.26E-07 11/114 R.VANYC[160.03]STHLLEHITTNEDFR.A "sp|O75688|PPM1B_HUMAN,tr|B8ZZF0|B8ZZF0_HUMAN,tr|A0A3B3IS24|A0A3B3IS24_HUMAN,tr|C9JIR6|C9JIR6_HUMAN" 4 2419.1227 2.71 120654 18354 4 2419.127962 605.7879 Protein phosphatase 1B OS=Homo sapiens OX=9606 GN=PPM1B PE=1 SV=1 5.27 3092.1 - 665798 - - - 2.1921 - 2.361 0.499 - 73.9 1 2 0 0.0053 20 0 0 0 5.33E+07 1.97E+07 - - - 3.855 1 221125_WJC_METTL3_EV_vs_WT_F08.18361.18361.3 1.98E-05 8/112 K.SSVSDAPVHITASGEPVPISEESEELDQK[136.11].T "sp|O14646|CHD1_HUMAN,tr|H0Y8V4|H0Y8V4_HUMAN,tr|A0A087WVF4|A0A087WVF4_HUMAN" 3 3044.4553 1.39 120658 18361 3 3044.452751 1015.8257 Chromodomain-helicase-DNA-binding protein 1 OS=Homo sapiens OX=9606 GN=CHD1 PE=1 SV=2 4 3093.1 - 145963 - - - -0.8488 - 2.002 0.532 - 35.2 1 2 0 -0.0026 29 0 0 0 7.82E+06 5.61E+06 - - - 6.0675 1 221125_WJC_METTL3_EV_vs_WT_F08.18363.18363.4 2.03E-09 17/144 K.DLPIHAC[160.03]SYC[160.03]GIHDPAC[160.03]VVYC[160.03]NTSK.K sp|Q92900|RENT1_HUMAN 1 2936.2714 1.94 120660 18363 4 2936.275393 735.0751 Regulator of nonsense transcripts 1 OS=Homo sapiens OX=9606 GN=UPF1 PE=1 SV=2 5.97 3093.3 - 264916 - - - 1.363 - 3.555 0.698 - 147.1 1 2 0 0.004 25 0 0 0 2.74E+07 1.41E+07 - - - 5.7038 0.9222 221125_WJC_METTL3_EV_vs_WT_F08.18364.18364.4 0.000125 9/144 R.LYKDDQLLDDGKTLGEC[160.03]GFTSQTAR.P "sp|Q15370|ELOB_HUMAN,tr|B8ZZU8|B8ZZU8_HUMAN" 2 2830.3443 0.04 120661 18364 4 2830.350519 708.5934 Elongin-B OS=Homo sapiens OX=9606 GN=ELOB PE=1 SV=1 4.36 3093.4 - 228326 - - - 2.1838 - 2.416 0.424 - 47 1 1 2 0.0062 25 0 0 0 2.90E+06 6.66E+07 - - - 3.1954 0.9998 221125_WJC_METTL3_EV_vs_WT_F08.18374.18374.4 9.86E-09 18/156 R.SLQTLPTDSSTFDTDTFC[160.03]PPR[166.11]PK[136.11]PVAR[166.11].K "sp|Q9NQG6|MID51_HUMAN,tr|B0QY95|B0QY95_HUMAN" 2 3061.5173 0.58 120667 18374 4 3061.530426 766.3866 Mitochondrial dynamics protein MID51 OS=Homo sapiens OX=9606 GN=MIEF1 PE=1 SV=1 5.76 3094.8 - 384319 - - - 4.2789 - 2.982 0.547 - 253 1 2 0 0.0131 27 0 0 0 8.03E+06 1.39E+07 - - - 4.3253 0.999 221125_WJC_METTL3_EV_vs_WT_F08.18376.18376.3 0.000807 Sep-80 R.ENFC[160.03]NIHVSLVPQPSSTGEQK.T "sp|P17812|PYRG1_HUMAN,tr|A0A3B3ITF6|A0A3B3ITF6_HUMAN,tr|B4E1E0|B4E1E0_HUMAN,tr|A0A3B3IRQ8|A0A3B3IRQ8_HUMAN,tr|A0A3B3ITB8|A0A3B3ITB8_HUMAN,tr|A0A3B3IRI2|A0A3B3IRI2_HUMAN" 6 2370.1274 0.85 120669 18376 3 2370.1372 791.0497 CTP synthase 1 OS=Homo sapiens OX=9606 GN=CTPS1 PE=1 SV=2 5.4 3095 - 219657 - - - 4.1306 - 2.122 0.425 - 34.3 1 2 0 0.0098 21 0 0 0 5.32E+07 6.22E+07 - - - 5.0794 0.9997 221125_WJC_METTL3_EV_vs_WT_F08.18379.18379.3 6.80E-05 Oct-44 R.YLYTLVITDKEK.A "sp|P63173|RL38_HUMAN,tr|J3KT73|J3KT73_HUMAN,tr|J3QL01|J3QL01_HUMAN" 3 1484.8126 1.04 120671 18379 3 1484.813984 495.9448 60S ribosomal protein L38 OS=Homo sapiens OX=9606 GN=RPL38 PE=1 SV=2 6.07 3095.4 - 155558 - - - 0.9005 - 1.866 0.485 - 79.2 1 2 1 0.0013 12 0 0 0 1.76E+07 1.69E+07 - - - 5.676 0.9996 221125_WJC_METTL3_EV_vs_WT_F08.18386.18386.4 9.08E-05 11/138 K.FTNSNTPNSYNHMDPDKLNGLWSR.L "sp|Q5JTV8|TOIP1_HUMAN,tr|J3KN66|J3KN66_HUMAN,tr|A0A0A0MSK5|A0A0A0MSK5_HUMAN" 3 2807.2722 1.81 120676 18386 4 2807.277753 702.8253 Torsin-1A-interacting protein 1 OS=Homo sapiens OX=9606 GN=TOR1AIP1 PE=1 SV=2 6.75 3096.3 - 345866 - - - 1.9866 - 2.231 0.451 - 58.9 1 2 1 0.0056 24 0 0 0 6.21E+06 3.42E+06 - - - 3.4075 0.9996 221125_WJC_METTL3_EV_vs_WT_F08.18392.18392.3 0.00485 Oct-44 R.YLYTLVITDK[136.11]EK[136.11].A "sp|P63173|RL38_HUMAN,tr|J3KT73|J3KT73_HUMAN,tr|J3QL01|J3QL01_HUMAN" 3 1500.841 1.04 120680 18392 3 1500.841625 501.2876 60S ribosomal protein L38 OS=Homo sapiens OX=9606 GN=RPL38 PE=1 SV=2 6.07 3097.1 - 492256 - - - 0.3851 - 2.188 0.414 - 96.5 1 2 1 0.0006 12 0 0 0 1.76E+07 1.69E+07 - - - 5.3259 0.9999 221125_WJC_METTL3_EV_vs_WT_F08.18394.18394.3 13.3 15/80 R.ENFC[160.03]NIHVSLVPQPSSTGEQK[136.11].T "sp|P17812|PYRG1_HUMAN,tr|A0A3B3ITF6|A0A3B3ITF6_HUMAN,tr|B4E1E0|B4E1E0_HUMAN,tr|A0A3B3IRQ8|A0A3B3IRQ8_HUMAN,tr|A0A3B3ITB8|A0A3B3ITB8_HUMAN,tr|A0A3B3IRI2|A0A3B3IRI2_HUMAN" 6 2378.1416 0.85 120682 18394 3 2378.146046 793.7211 CTP synthase 1 OS=Homo sapiens OX=9606 GN=CTPS1 PE=1 SV=2 5.4 3097.4 - 550534 - - - 1.8653 - 3.149 0.474 - 141 1 2 0 0.0044 21 0 0 0 5.32E+07 6.29E+07 - - - 6.5735 1 221125_WJC_METTL3_EV_vs_WT_F08.18396.18396.2 8.47E-09 14/34 K.PSTASAVPELATDPELEK[136.11].K "sp|Q86U44|MTA70_HUMAN,tr|B4E349|B4E349_HUMAN,tr|F5H6D8|F5H6D8_HUMAN,tr|H0YFV6|H0YFV6_HUMAN,tr|B4DTN4|B4DTN4_HUMAN" 5 1861.94 0.001 120684 18396 2 1861.938273 931.9773 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 4 3097.6 - 265947 - - - -0.9485 - 2.898 0.591 - 323.4 1 1 0 -0.0018 18 0 0 0 0.00E+00 2.12E+07 - - - 6.0215 0.9981 221125_WJC_METTL3_EV_vs_WT_F08.18401.18401.4 6.65E-07 17/180 R.VPTHTLAMVVPPQEPDRTSQENSPALLGVQK.G "sp|Q8IWZ3|ANKH1_HUMAN,tr|E9PDP5|E9PDP5_HUMAN,tr|H7C2F5|H7C2F5_HUMAN" 3 3338.7293 2.48 120686 18401 4 3338.727645 835.6896 Ankyrin repeat and KH domain-containing protein 1 OS=Homo sapiens OX=9606 GN=ANKHD1 PE=1 SV=1 5.44 3098.3 - 802802 - - - -0.4885 - 2.969 0.323 - 69.2 1 2 1 -0.0016 31 0 0 0 2.23E+07 8.98E+06 - - - 2.3677 0.9998 221125_WJC_METTL3_EV_vs_WT_F08.18440.18440.3 4.94E-08 16/56 K.HKELAPYDENWFYTR.A "sp|P39019|RS19_HUMAN,tr|M0R140|M0R140_HUMAN,tr|M0R2L9|M0R2L9_HUMAN,tr|M0QYF7|M0QYF7_HUMAN" 4 1967.9166 1.18 120705 18440 3 1967.911349 656.9795 40S ribosomal protein S19 OS=Homo sapiens OX=9606 GN=RPS19 PE=1 SV=2 5.45 3103.4 - 1.33E+06 - - - -2.6744 - 3.333 0.563 - 378.9 1 2 1 -0.0053 15 0 0 0 1.09E+08 9.26E+07 - - - 7.9568 0.9997 221125_WJC_METTL3_EV_vs_WT_F08.18441.18441.3 1.60E-08 18/56 K.HK[136.11]ELAPYDENWFYTR[166.11].A "sp|P39019|RS19_HUMAN,tr|M0R140|M0R140_HUMAN,tr|M0R2L9|M0R2L9_HUMAN,tr|M0QYF7|M0QYF7_HUMAN" 4 1985.9391 1.18 120706 18441 3 1985.93249 662.987 40S ribosomal protein S19 OS=Homo sapiens OX=9606 GN=RPS19 PE=1 SV=2 5.45 3103.5 - 1.19E+06 - - - -3.3193 - 3.246 0.566 - 379.5 1 2 1 -0.0066 15 0 0 0 1.09E+08 9.26E+07 - - - 7.9208 0.9993 221125_WJC_METTL3_EV_vs_WT_F08.18446.18446.4 6.73E-06 16/84 K.HK[136.11]ELAPYDENWFYTR[166.11].A "sp|P39019|RS19_HUMAN,tr|M0R140|M0R140_HUMAN,tr|M0R2L9|M0R2L9_HUMAN,tr|M0QYF7|M0QYF7_HUMAN" 4 1985.9391 1.04 120709 18446 4 1985.930838 497.492 40S ribosomal protein S19 OS=Homo sapiens OX=9606 GN=RPS19 PE=1 SV=2 5.45 3104.2 - 936752 - - - -4.1512 - 2.798 0.538 - 177.3 1 2 1 -0.0082 15 0 0 0 5.86E+07 5.61E+07 - - - 4.2746 1 221125_WJC_METTL3_EV_vs_WT_F08.18447.18447.4 2.66E-08 18/84 K.HKELAPYDENWFYTR.A "sp|P39019|RS19_HUMAN,tr|M0R140|M0R140_HUMAN,tr|M0R2L9|M0R2L9_HUMAN,tr|M0QYF7|M0QYF7_HUMAN" 4 1967.9166 1.04 120710 18447 4 1967.917339 492.9864 40S ribosomal protein S19 OS=Homo sapiens OX=9606 GN=RPS19 PE=1 SV=2 5.45 3104.3 - 1.13E+06 - - - 0.3694 - 2.733 0.633 - 262.2 1 2 1 0.0007 15 0 0 0 5.85E+07 5.61E+07 - - - 5.0952 1 221125_WJC_METTL3_EV_vs_WT_F08.18455.18455.4 9.35E-15 26/138 R.KSPTMEQAVQTASAHLPAPAAVGR.R sp|Q8ND56|LS14A_HUMAN 1 2417.2485 1.16 120715 18455 4 2417.240952 605.3194 Protein LSM14 homolog A OS=Homo sapiens OX=9606 GN=LSM14A PE=1 SV=3 8.75 3105.3 - 1.03E+06 - - - -3.1341 - 4.944 0.658 - 310.2 1 2 0 -0.0076 24 0 0 0 3.52E+08 3.05E+08 - - - 5.4641 0.8681 221125_WJC_METTL3_EV_vs_WT_F08.18460.18460.3 0.0931 Oct-44 K.QKVDSLLENLEK.L "sp|P0DMR1|HNRC4_HUMAN,sp|P07910|HNRPC_HUMAN,sp|O60812|HNRC1_HUMAN,sp|B2RXH8|HNRC2_HUMAN,sp|B7ZW38|HNRC3_HUMAN,tr|B4DY08|B4DY08_HUMAN,tr|G3V5V7|G3V5V7_HUMAN,tr|B2R5W2|B2R5W2_HUMAN,tr|G3V4C1|G3V4C1_HUMAN,tr|A0A0G2JPF8|A0A0G2JPF8_HUMAN,tr|A0A0G2JNQ3|A0A0G2JNQ3_HUMAN,tr|G3V576|G3V576_HUMAN,tr|G3V2D6|G3V2D6_HUMAN,tr|G3V4W0|G3V4W0_HUMAN,tr|G3V2Q1|G3V2Q1_HUMAN" 15 1414.7668 1.52 120717 18460 3 1414.764598 472.5962 Heterogeneous nuclear ribonucleoprotein C-like 4 OS=Homo sapiens OX=9606 GN=HNRNPCL4 PE=3 SV=1 4.68 3105.9 - 432697 - - - -1.5282 - 1.745 0.107 - 136.2 1 2 1 -0.0022 12 0 0 0 3.01E+07 1.99E+07 - - - 1.2756 0.9995 221125_WJC_METTL3_EV_vs_WT_F08.18467.18467.4 0.000543 19/192 R.SDSPVPTAPTSGGPK[136.11]PSTASAVPELATDPELEK[136.11].K "sp|Q86U44|MTA70_HUMAN,tr|B4E349|B4E349_HUMAN,tr|F5H6D8|F5H6D8_HUMAN,tr|B4DTN4|B4DTN4_HUMAN" 4 3248.6271 0.04 120719 18467 4 3248.61843 813.1641 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 4.18 3106.9 - 2.58E+06 - - - -2.6682 - 2.797 0.374 - 109 1 2 0 -0.0087 33 0 0 0 5.65E+06 1.38E+08 - - - 2.7875 0.9886 221125_WJC_METTL3_EV_vs_WT_F08.18476.18476.4 0.000105 10/168 R.PQSC[160.03]HPC[160.03]C[160.03]YKPEAPGC[160.03]EAPDHLQGLGVPI.- sp|Q8N5Z5|KCD17_HUMAN 1 3273.4464 5.07 120723 18476 4 3273.454779 819.3689 BTB\POZ domain-containing protein KCTD17 OS=Homo sapiens OX=9606 GN=KCTD17 PE=1 SV=3 5.28 3108.1 - 722910 - - - 2.5612 - 1.909 0.5 - 21 1 1 0 0.0084 29 0 0 0 2.58E+08 5.09E+07 - - - 3.7749 1 221125_WJC_METTL3_EV_vs_WT_F08.18479.18479.4 1.28E-06 13/120 K.EK[136.11]PSYDTETDPSEGLMNVLK[136.11]K[136.11].L sp|Q9HB71|CYBP_HUMAN 1 2404.1894 0.31 120724 18479 4 2404.187867 602.0546 Calcyclin-binding protein OS=Homo sapiens OX=9606 GN=CACYBP PE=1 SV=2 4.51 3108.5 - 394709 - - - -0.6405 - 2.271 0.538 - 74.5 1 2 0 -0.0015 21 0 0 0 1.60E+07 5.22E+07 - - - 4.1795 1 221125_WJC_METTL3_EV_vs_WT_F08.18481.18481.4 2.32E-08 23/138 R.K[136.11]SPTMEQAVQTASAHLPAPAAVGR[166.11].R sp|Q8ND56|LS14A_HUMAN 1 2435.271 1.15 120725 18481 4 2435.269749 609.825 Protein LSM14 homolog A OS=Homo sapiens OX=9606 GN=LSM14A PE=1 SV=3 8.75 3108.7 - 1.37E+06 - - - -0.5129 - 3.694 0.595 - 214.5 1 2 0 -0.0012 24 0 0 0 3.69E+08 3.20E+08 - - - 4.8239 1 221125_WJC_METTL3_EV_vs_WT_F08.18485.18485.3 1.92E-11 23/76 K.TSHSSTEAC[160.03]C[160.03]ELC[160.03]GLYFENR.K "sp|O95785|WIZ_HUMAN,tr|A0A669KBG4|A0A669KBG4_HUMAN,tr|A0A2R8YFV2|A0A2R8YFV2_HUMAN,tr|A0A669KAV7|A0A669KAV7_HUMAN,tr|M0QXA7|M0QXA7_HUMAN,tr|A0A669KBH9|A0A669KBH9_HUMAN,tr|B9EGQ5|B9EGQ5_HUMAN" 7 2419.9831 1.71 120727 18485 3 2419.981457 807.6683 Protein Wiz OS=Homo sapiens OX=9606 GN=WIZ PE=1 SV=2 4.75 3109.2 - 1.30E+06 - - - -0.6913 - 3.503 0.731 - 564.5 1 2 0 -0.0017 20 0 0 0 6.02E+07 3.52E+07 - - - 9.7308 1 221125_WJC_METTL3_EV_vs_WT_F08.18487.18487.3 4.19E-10 18/76 K.TSHSSTEAC[160.03]C[160.03]ELC[160.03]GLYFENR[166.11].K "sp|O95785|WIZ_HUMAN,tr|A0A669KBG4|A0A669KBG4_HUMAN,tr|A0A2R8YFV2|A0A2R8YFV2_HUMAN,tr|A0A669KAV7|A0A669KAV7_HUMAN,tr|M0QXA7|M0QXA7_HUMAN,tr|A0A669KBH9|A0A669KBH9_HUMAN,tr|B9EGQ5|B9EGQ5_HUMAN" 7 2429.9914 1.71 120728 18487 3 2429.98945 811.0044 Protein Wiz OS=Homo sapiens OX=9606 GN=WIZ PE=1 SV=2 4.75 3109.4 - 1.29E+06 - - - -0.8025 - 3.275 0.724 - 326.1 1 2 0 -0.0019 20 0 0 0 6.02E+07 3.52E+07 - - - 9.4894 0.973 221125_WJC_METTL3_EV_vs_WT_F08.18502.18502.3 9.97E-06 18/88 K.QSKPVTTPEEIAQVATISANGDK.E "sp|P10809|CH60_HUMAN,tr|A0A7I2V599|A0A7I2V599_HUMAN,tr|E7EXB4|E7EXB4_HUMAN,tr|A0A7I2YQ71|A0A7I2YQ71_HUMAN,tr|E7ESH4|E7ESH4_HUMAN,tr|A0A7I2V5M1|A0A7I2V5M1_HUMAN,tr|A0A7I2V5K3|A0A7I2V5K3_HUMAN,tr|A0A7I2V369|A0A7I2V369_HUMAN" 8 2383.2231 1.59 120736 18502 3 2384.215104 795.415 "60 kDa heat shock protein, mitochondrial OS=Homo sapiens OX=9606 GN=HSPD1 PE=1 SV=2" 4.68 3111.2 - 888316 - - - 416.2514 - 2.637 0.448 - 235.1 1 2 0 0.992 23 0 0 0 1.77E+08 1.12E+08 - - - 5.5347 0.9995 221125_WJC_METTL3_EV_vs_WT_F08.18506.18506.4 0.000215 Nov-84 R.GFC[160.03]FITFKEEEPVKK.L "sp|Q14103|HNRPD_HUMAN,tr|H0Y8G5|H0Y8G5_HUMAN,tr|H0YA96|H0YA96_HUMAN" 3 1857.9335 1.07 120738 18506 4 1857.938083 465.4907 Heterogeneous nuclear ribonucleoprotein D0 OS=Homo sapiens OX=9606 GN=HNRNPD PE=1 SV=1 6.22 3111.7 - 340814 - - - 2.4624 - 1.68 0.471 - 62.7 1 2 1 0.0046 15 0 0 0 1.11E+07 1.03E+07 - - - 3.5099 0.9996 221125_WJC_METTL3_EV_vs_WT_F08.18508.18508.4 7.78E-09 18/114 K.SFPK[136.11]DDPSK[136.11]PVHLTAFLGYK[136.11].A "sp|P39023|RL3_HUMAN,tr|H7C3M2|H7C3M2_HUMAN,tr|F8WCR1|F8WCR1_HUMAN,tr|H7C422|H7C422_HUMAN" 4 2270.2162 0.98 120740 18508 4 2270.208223 568.5613 60S ribosomal protein L3 OS=Homo sapiens OX=9606 GN=RPL3 PE=1 SV=2 8.18 3112 - 795153 - - - -3.4939 - 3.034 0.544 - 125.5 1 2 1 -0.0079 20 0 0 0 6.86E+07 7.01E+07 - - - 4.3298 0.9998 221125_WJC_METTL3_EV_vs_WT_F08.18517.18517.4 1.88E-05 20/144 R.VGTVIGSNK[136.11]LEQMPSK[136.11]EDAIEHFMK[136.11].L "sp|P09874|PARP1_HUMAN,tr|A0A7I2V3E1|A0A7I2V3E1_HUMAN" 2 2811.4361 0.99 120743 18517 4 2811.438554 703.8663 Poly [ADP-ribose] polymerase 1 OS=Homo sapiens OX=9606 GN=PARP1 PE=1 SV=4 5.53 3113.3 - 640434 - - - 0.8597 - 3.897 0.46 - 223.1 1 2 2 0.0024 25 0 0 0 4.22E+07 4.28E+07 - - - 3.6619 1 221125_WJC_METTL3_EV_vs_WT_F08.18520.18520.4 6.19E-14 27/114 K.DK[136.11]LESEMEDAYHEHQANLLR[166.11].Q "sp|P23246|SFPQ_HUMAN,tr|H0Y9K7|H0Y9K7_HUMAN" 2 2445.135 0.86 120744 18520 4 2445.133097 612.291 "Splicing factor, proline- and glutamine-rich OS=Homo sapiens OX=9606 GN=SFPQ PE=1 SV=2" 4.63 3113.7 - 1.30E+06 - - - -0.7611 - 4.373 0.674 - 878.5 1 2 1 -0.0019 20 0 0 0 3.74E+08 4.34E+08 - - - 5.5853 0.9995 221125_WJC_METTL3_EV_vs_WT_F08.18521.18521.4 9.72E-05 17/144 R.VGTVIGSNKLEQMPSKEDAIEHFMK.L "sp|P09874|PARP1_HUMAN,tr|A0A7I2V3E1|A0A7I2V3E1_HUMAN" 2 2787.3935 0.99 120745 18521 4 2787.387841 697.8557 Poly [ADP-ribose] polymerase 1 OS=Homo sapiens OX=9606 GN=PARP1 PE=1 SV=4 5.53 3113.8 - 779532 - - - -2.0435 - 3.094 0.426 - 93.3 1 2 2 -0.0057 25 0 0 0 4.22E+07 4.28E+07 - - - 3.2916 0.9999 221125_WJC_METTL3_EV_vs_WT_F08.18526.18526.3 5.66E-05 19/124 K.TPETVVPTAPELQPSTSTDQPVTPEPTSQATR.G sp|Q14676|MDC1_HUMAN 1 3361.6525 2.16 120748 18526 3 3361.666148 1121.5581 Mediator of DNA damage checkpoint protein 1 OS=Homo sapiens OX=9606 GN=MDC1 PE=1 SV=3 4 3114.5 - 398203 - - - 4.0525 - 3.111 0.544 - 209.8 1 2 0 0.0136 32 0 0 0 1.99E+07 9.19E+06 - - - 7.2124 1 221125_WJC_METTL3_EV_vs_WT_F08.18529.18529.4 8.72E-11 22/114 K.DKLESEMEDAYHEHQANLLR.Q "sp|P23246|SFPQ_HUMAN,tr|H0Y9K7|H0Y9K7_HUMAN" 2 2427.1125 0.86 120749 18529 4 2427.115798 607.7854 "Splicing factor, proline- and glutamine-rich OS=Homo sapiens OX=9606 GN=SFPQ PE=1 SV=2" 4.63 3114.9 - 3.13E+06 - - - 1.3638 - 4.448 0.68 - 575.2 1 2 1 0.0033 20 0 0 0 3.73E+08 4.34E+08 - - - 5.6428 1 221125_WJC_METTL3_EV_vs_WT_F08.18540.18540.3 2.72E-08 15/92 R.KSPTMEQAVQTASAHLPAPAAVGR.R sp|Q8ND56|LS14A_HUMAN 1 2417.2485 1.21 120756 18540 3 2417.250146 806.7568 Protein LSM14 homolog A OS=Homo sapiens OX=9606 GN=LSM14A PE=1 SV=3 8.75 3116.3 - 712606 - - - 0.6694 - 3.146 0.55 - 82.4 1 2 0 0.0016 24 0 0 0 1.26E+08 1.04E+08 - - - 7.3335 0.9998 221125_WJC_METTL3_EV_vs_WT_F08.18541.18541.4 1.61E-05 Oct-84 R.GFC[160.03]FITFK[136.11]EEEPVK[136.11]K[136.11].L "sp|Q14103|HNRPD_HUMAN,tr|H0Y8G5|H0Y8G5_HUMAN,tr|H0YA96|H0YA96_HUMAN" 3 1881.9761 1.07 120757 18541 4 1881.977863 471.5013 Heterogeneous nuclear ribonucleoprotein D0 OS=Homo sapiens OX=9606 GN=HNRNPD PE=1 SV=1 6.22 3116.5 - 365102 - - - 0.9325 - 1.836 0.469 - 53.3 1 2 1 0.0018 15 0 0 0 1.11E+07 1.03E+07 - - - 3.5251 0.9948 221125_WJC_METTL3_EV_vs_WT_F08.18542.18542.4 3.30E-06 9/156 Q.SC[160.03]HPC[160.03]C[160.03]YKPEAPGC[160.03]EAPDHLQGLGVPI.- sp|Q8N5Z5|KCD17_HUMAN 1 3048.3351 4.82 120758 18542 4 3048.334604 763.091 BTB\POZ domain-containing protein KCTD17 OS=Homo sapiens OX=9606 GN=KCTD17 PE=1 SV=3 5.26 3116.6 - 529278 - - - -0.1476 - 2.04 0.494 - 17 1 1 0 -0.0004 27 0 0 0 3.75E+07 7.78E+06 - - - 3.7487 1 221125_WJC_METTL3_EV_vs_WT_F08.18547.18547.3 1.66E-11 24/76 K.DKLESEMEDAYHEHQANLLR.Q "sp|P23246|SFPQ_HUMAN,tr|H0Y9K7|H0Y9K7_HUMAN" 2 2427.1125 0.87 120761 18547 3 2427.113045 810.0448 "Splicing factor, proline- and glutamine-rich OS=Homo sapiens OX=9606 GN=SFPQ PE=1 SV=2" 4.63 3117.3 - 748953 - - - 0.2295 - 4.764 0.743 - 1001.6 1 2 1 0.0006 20 0 0 0 3.09E+07 3.57E+07 - - - 10.6108 1 221125_WJC_METTL3_EV_vs_WT_F08.18550.18550.3 3.87E-06 15/124 R.GKPLLLSAPGGQEDPAPEIPSSAPAAPSSAPR.T "sp|Q13487|SNPC2_HUMAN,tr|M0QXY9|M0QXY9_HUMAN" 2 3064.5829 5.09 120764 18550 3 3064.582539 1022.5349 snRNA-activating protein complex subunit 2 OS=Homo sapiens OX=9606 GN=SNAPC2 PE=1 SV=1 4.68 3117.6 - 262573 - - - -0.1273 - 2.624 0.585 - 95.3 1 2 0 -0.0004 32 0 0 0 1.11E+07 2.18E+06 - - - 7.2815 0.8651 221125_WJC_METTL3_EV_vs_WT_F08.18551.18551.3 0.316 Aug-72 K.QGAPTSFLPPEASQLK[136.11]PDR[166.11].Q "sp|Q9BUJ2|HNRL1_HUMAN,tr|M0R0K8|M0R0K8_HUMAN,tr|M0QYZ0|M0QYZ0_HUMAN,tr|A0A0A0MRA5|A0A0A0MRA5_HUMAN,tr|M0QZV6|M0QZV6_HUMAN,tr|B7Z4B8|B7Z4B8_HUMAN,tr|M0QYI8|M0QYI8_HUMAN,tr|M0R203|M0R203_HUMAN" 8 2056.0708 1.37 120765 18551 3 2056.074306 686.3642 Heterogeneous nuclear ribonucleoprotein U-like protein 1 OS=Homo sapiens OX=9606 GN=HNRNPUL1 PE=1 SV=2 6.07 3117.8 - 137211 - - - 1.6935 - 1.516 0.086 - 51.7 1 2 0 0.0035 19 0 0 0 5.82E+06 4.24E+06 - - - 0.5201 1 221125_WJC_METTL3_EV_vs_WT_F08.18568.18568.4 4.26E-09 23/162 R.HVVFTAETHNFPTGVC[160.03]PFSGATTGTGGR[166.11].L sp|O15067|PUR4_HUMAN 1 2914.3696 0.64 120774 18568 4 2914.377181 729.5997 Phosphoribosylformylglycinamidine synthase OS=Homo sapiens OX=9606 GN=PFAS PE=1 SV=4 6.91 3120 - 544750 - - - 2.6026 - 4.393 0.617 - 365.9 1 2 0 0.0076 28 0 0 0 1.40E+07 2.19E+07 - - - 5.0538 0.9989 221125_WJC_METTL3_EV_vs_WT_F08.18578.18578.4 0.00135 15/84 R.STSHK[136.11]PDEIYGMIER[166.11].L sp|Q86U44|MTA70_HUMAN 1 1779.8581 0.02 120779 18578 4 1779.860861 445.9718 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 5.42 3121.3 - 260637 - - - 1.5771 - 2.442 0.295 - 135.1 1 2 0 0.0028 15 0 0 0 5.45E+05 2.25E+07 - - - 2.1124 0.9999 221125_WJC_METTL3_EV_vs_WT_F08.18584.18584.4 1.44E-08 20/120 R.DSFDDRGPSLNPVLDYDHGSR.S "sp|P43243|MATR3_HUMAN,tr|A8MXP9|A8MXP9_HUMAN,tr|D6R991|D6R991_HUMAN,tr|A0A0R4J2E8|A0A0R4J2E8_HUMAN,tr|D6REM6|D6REM6_HUMAN" 5 2361.0622 1.31 120783 18584 4 2361.065567 591.2728 Matrin-3 OS=Homo sapiens OX=9606 GN=MATR3 PE=1 SV=2 4.28 3122.1 - 1.04E+06 - - - 1.4405 - 3.487 0.545 - 306.6 1 2 1 0.0034 21 0 0 0 3.20E+07 2.44E+07 - - - 4.3817 0.9999 221125_WJC_METTL3_EV_vs_WT_F08.18585.18585.4 2.29E-07 17/120 R.DSFDDR[166.11]GPSLNPVLDYDHGSR[166.11].S "sp|P43243|MATR3_HUMAN,tr|A8MXP9|A8MXP9_HUMAN,tr|D6R991|D6R991_HUMAN,tr|A0A0R4J2E8|A0A0R4J2E8_HUMAN,tr|D6REM6|D6REM6_HUMAN" 5 2381.0787 1.32 120784 18585 4 2381.074377 596.277 Matrin-3 OS=Homo sapiens OX=9606 GN=MATR3 PE=1 SV=2 4.28 3122.2 - 762351 - - - -1.8181 - 3.441 0.579 - 205.1 1 2 1 -0.0043 21 0 0 0 3.22E+07 2.44E+07 - - - 4.673 1 221125_WJC_METTL3_EV_vs_WT_F08.18586.18586.3 1.15E-12 25/100 K.RPSTSQTVSTPAPVPVIESTEAIEAK.A sp|P12270|TPR_HUMAN 1 2694.4076 9.02 120785 18586 3 2694.411085 899.1431 Nucleoprotein TPR OS=Homo sapiens OX=9606 GN=TPR PE=1 SV=3 4.79 3122.3 - 477793 - - - 1.2971 - 4.572 0.677 - 618.9 1 2 0 0.0035 26 0 0 0 4.97E+07 5.51E+06 - - - 9.5838 0.9999 221125_WJC_METTL3_EV_vs_WT_F08.18606.18606.3 6.96E-08 17/80 R.DSFDDRGPSLNPVLDYDHGSR.S "sp|P43243|MATR3_HUMAN,tr|A8MXP9|A8MXP9_HUMAN,tr|D6R991|D6R991_HUMAN,tr|A0A0R4J2E8|A0A0R4J2E8_HUMAN,tr|D6REM6|D6REM6_HUMAN" 5 2361.0622 1.91 120799 18606 3 2361.060707 788.028 Matrin-3 OS=Homo sapiens OX=9606 GN=MATR3 PE=1 SV=2 4.28 3125 - 461176 - - - -0.6179 - 2.999 0.576 - 353.3 1 2 1 -0.0015 21 0 0 0 5.60E+06 2.93E+06 - - - 7.5945 0.9999 221125_WJC_METTL3_EV_vs_WT_F08.18607.18607.3 0.00973 Nov-44 R.EHALLAYTLGVK[136.11].Q "sp|Q05639|EF1A2_HUMAN,sp|P68104|EF1A1_HUMAN,sp|Q5VTE0|EF1A3_HUMAN,tr|A0A2R8Y488|A0A2R8Y488_HUMAN,tr|A0A7I2V659|A0A7I2V659_HUMAN,tr|A0A7I2V3H3|A0A7I2V3H3_HUMAN,tr|A0A2U3TZH3|A0A2U3TZH3_HUMAN,tr|A0A7I2V5N4|A0A7I2V5N4_HUMAN,tr|A0A087WVQ9|A0A087WVQ9_HUMAN,tr|A0A087WV01|A0A087WV01_HUMAN,tr|A0A2R8Y660|A0A2R8Y660_HUMAN" 11 1321.7485 0.74 120800 18607 3 1321.748275 441.5901 Elongation factor 1-alpha 2 OS=Homo sapiens OX=9606 GN=EEF1A2 PE=1 SV=1 6.85 3125.1 - 228453 - - - -0.1982 - 2.203 0.434 - 186.1 1 2 0 -0.0003 12 0 0 0 2.87E+06 3.87E+06 - - - 5.5679 0.9999 221125_WJC_METTL3_EV_vs_WT_F08.18609.18609.4 1.16E-07 22/162 K.QHQPTPQPALPYNHIYSYPSPITAAAAK.V sp|P55771|PAX9_HUMAN 1 3060.5458 3.99 120801 18609 4 3060.55814 766.1437 Paired box protein Pax-9 OS=Homo sapiens OX=9606 GN=PAX9 PE=1 SV=3 8.45 3125.3 - 745091 - - - 4.0463 - 3.7 0.547 - 227 1 2 0 0.0124 28 0 0 0 2.14E+07 5.36E+06 - - - 4.3899 0.9999 221125_WJC_METTL3_EV_vs_WT_F08.18619.18619.4 0.000174 22/144 R.SRPPEERPPGLPLPPPPPSSSAVFR.L sp|P48634|PRC2A_HUMAN 1 2663.4184 9.63 120808 18619 4 2663.420874 666.8619 Protein PRRC2A OS=Homo sapiens OX=9606 GN=PRRC2A PE=1 SV=3 9.23 3126.6 - 942605 - - - 0.9401 - 3.174 0.439 - 179.3 1 2 0 0.0025 25 0 0 0 2.46E+07 2.55E+06 - - - 3.4138 1 221125_WJC_METTL3_EV_vs_WT_F08.18620.18620.4 4.34E-11 27/126 R.HLC[160.03]IC[160.03]SVDPPGC[160.03]TDIDDALHC[160.03]R.E "sp|Q9Y2L1|RRP44_HUMAN,tr|F2Z2C0|F2Z2C0_HUMAN,tr|G3V1J5|G3V1J5_HUMAN" 3 2610.1083 1.45 120809 18620 4 2610.116924 653.5344 Exosome complex exonuclease RRP44 OS=Homo sapiens OX=9606 GN=DIS3 PE=1 SV=2 4.54 3126.7 - 1.12E+06 - - - 3.2857 - 5.096 0.72 - 557.5 1 2 0 0.0086 22 0 0 0 2.98E+07 2.06E+07 - - - 6.0233 0.9997 221125_WJC_METTL3_EV_vs_WT_F08.18628.18628.3 8.70E-06 Oct-64 K.GQPSNKEDVDDLVSQLR.Q sp|P12270|TPR_HUMAN 1 1898.9334 2.57 120813 18628 3 1898.937221 633.9851 Nucleoprotein TPR OS=Homo sapiens OX=9606 GN=TPR PE=1 SV=3 4.23 3127.6 - 558139 - - - 2.0206 - 2.328 0.52 - 79.2 1 2 1 0.0038 17 0 0 0 1.21E+07 4.70E+06 - - - 6.4712 1 221125_WJC_METTL3_EV_vs_WT_F08.18633.18633.4 3.57E-12 30/126 R.HLC[160.03]IC[160.03]SVDPPGC[160.03]TDIDDALHC[160.03]R[166.11].E "sp|Q9Y2L1|RRP44_HUMAN,tr|F2Z2C0|F2Z2C0_HUMAN,tr|G3V1J5|G3V1J5_HUMAN" 3 2620.1166 1.38 120816 18633 4 2620.116042 656.0364 Exosome complex exonuclease RRP44 OS=Homo sapiens OX=9606 GN=DIS3 PE=1 SV=2 4.54 3128.3 - 1.14E+06 - - - -0.2198 - 5.749 0.747 - 934.3 1 2 0 -0.0006 22 0 0 0 2.98E+07 2.17E+07 - - - 6.3 1 221125_WJC_METTL3_EV_vs_WT_F08.18634.18634.2 0.152 18-Dec L.PGDNVGFNVK[136.11].N "sp|Q05639|EF1A2_HUMAN,sp|P68104|EF1A1_HUMAN,tr|A0A7I2V659|A0A7I2V659_HUMAN,tr|A0A7I2V3H3|A0A7I2V3H3_HUMAN,tr|A0A2U3TZH3|A0A2U3TZH3_HUMAN,tr|A0A7I2V5N4|A0A7I2V5N4_HUMAN,tr|A0A087WVQ9|A0A087WVQ9_HUMAN,tr|A0A087WV01|A0A087WV01_HUMAN" 8 1053.5335 1.95 120817 18634 2 1053.533635 527.774 Elongation factor 1-alpha 2 OS=Homo sapiens OX=9606 GN=EEF1A2 PE=1 SV=1 6.26 3128.4 - 308913 - - - 0.1671 - 2.865 0.536 - 777.1 1 1 0 0.0002 10 0 0 0 1.29E+07 6.61E+06 - - - 5.9379 0.9999 221125_WJC_METTL3_EV_vs_WT_F08.18640.18640.4 7.52E-06 18/132 R.IVSR[166.11]PEELR[166.11]EDDVGTGAGLLEIK[136.11].K "sp|P49368|TCPG_HUMAN,tr|B4DUR8|B4DUR8_HUMAN" 2 2523.3539 0.2 120821 18640 4 2523.351176 631.8457 T-complex protein 1 subunit gamma OS=Homo sapiens OX=9606 GN=CCT3 PE=1 SV=4 4.36 3129.2 - 1.02E+06 - - - -1.0684 - 3.149 0.52 - 173.7 1 2 1 -0.0027 23 0 0 0 6.55E+06 3.26E+07 - - - 4.123 1 221125_WJC_METTL3_EV_vs_WT_F08.18643.18643.3 9.34E-07 19/52 R.KVESLQEEIAFLKK.L "sp|P08670|VIME_HUMAN,tr|B0YJC5|B0YJC5_HUMAN,tr|B0YJC4|B0YJC4_HUMAN" 3 1660.94 1.91 120824 18643 3 1660.940942 554.6539 Vimentin OS=Homo sapiens OX=9606 GN=VIM PE=1 SV=4 6.23 3129.6 - 838952 - - - 0.5834 - 3.682 0.568 - 507.2 1 2 0 0.001 14 0 0 0 3.42E+07 1.79E+07 - - - 8.3363 0.9995 221125_WJC_METTL3_EV_vs_WT_F08.18644.18644.4 1.86E-06 13/78 R.K[136.11]VESLQEEIAFLK[136.11]K[136.11].L "sp|P08670|VIME_HUMAN,tr|B0YJC5|B0YJC5_HUMAN,tr|B0YJC4|B0YJC4_HUMAN" 3 1684.9826 1.71 120825 18644 4 1684.981974 422.2529 Vimentin OS=Homo sapiens OX=9606 GN=VIM PE=1 SV=4 6.23 3129.7 - 524711 - - - -0.3555 - 2.241 0.33 - 153.3 1 2 0 -0.0006 14 0 0 0 1.84E+07 1.07E+07 - - - 2.3918 0.9998 221125_WJC_METTL3_EV_vs_WT_F08.18645.18645.4 0.00233 15/78 R.KVESLQEEIAFLKK.L "sp|P08670|VIME_HUMAN,tr|B0YJC5|B0YJC5_HUMAN,tr|B0YJC4|B0YJC4_HUMAN" 3 1660.94 1.71 120826 18645 4 1660.936237 416.2423 Vimentin OS=Homo sapiens OX=9606 GN=VIM PE=1 SV=4 6.23 3129.8 - 492607 - - - -2.2493 - 2.556 0.424 - 226.5 1 2 0 -0.0037 14 0 0 0 1.84E+07 1.08E+07 - - - 3.257 1 221125_WJC_METTL3_EV_vs_WT_F08.18649.18649.3 2.24E-08 19/112 K.TPETVVPTAPELQISTSTDQPVTPKPTSR.T sp|Q14676|MDC1_HUMAN 1 3076.5928 2.27 120828 18649 3 3076.598262 1026.5382 Mediator of DNA damage checkpoint protein 1 OS=Homo sapiens OX=9606 GN=MDC1 PE=1 SV=3 4.68 3130.4 - 737016 - - - 1.7672 - 3.961 0.673 - 197.4 1 2 0 0.0054 29 0 0 0 2.38E+07 1.05E+07 - - - 9.2086 1 221125_WJC_METTL3_EV_vs_WT_F08.18651.18651.3 1.85E-06 21/84 R.HLC[160.03]IC[160.03]SVDPPGC[160.03]TDIDDALHC[160.03]R.E "sp|Q9Y2L1|RRP44_HUMAN,tr|F2Z2C0|F2Z2C0_HUMAN,tr|G3V1J5|G3V1J5_HUMAN" 3 2610.1083 2.62 120830 18651 3 2610.106639 871.0434 Exosome complex exonuclease RRP44 OS=Homo sapiens OX=9606 GN=DIS3 PE=1 SV=2 4.54 3130.6 - 670020 - - - -0.6548 - 3.911 0.734 - 409.4 1 2 0 -0.0017 22 0 0 0 9.98E+06 3.81E+06 - - - 9.9562 0.9192 221125_WJC_METTL3_EV_vs_WT_F08.18660.18660.4 0.00269 13/96 S.ANGDK[136.11]EIGNIISDAMK[136.11]K[136.11].V "sp|P10809|CH60_HUMAN,tr|A0A7I2V599|A0A7I2V599_HUMAN,tr|E7EXB4|E7EXB4_HUMAN,tr|A0A7I2YQ71|A0A7I2YQ71_HUMAN,tr|E7ESH4|E7ESH4_HUMAN,tr|A0A7I2V5M1|A0A7I2V5M1_HUMAN,tr|A0A7I2V5K3|A0A7I2V5K3_HUMAN,tr|A0A7I2V369|A0A7I2V369_HUMAN" 8 1826.9622 1.14 120837 18660 4 1826.962369 457.7478 "60 kDa heat shock protein, mitochondrial OS=Homo sapiens OX=9606 GN=HSPD1 PE=1 SV=2" 6.16 3131.6 - 429201 - - - 0.0662 - 2.617 0.378 - 108 1 1 1 0.0001 17 0 0 0 3.84E+07 3.36E+07 - - - 2.8501 0.9436 221125_WJC_METTL3_EV_vs_WT_F08.18663.18663.4 0.0829 Dec-96 S.ANGDKEIGNIISDAMKK.V "sp|P10809|CH60_HUMAN,tr|A0A7I2V599|A0A7I2V599_HUMAN,tr|E7EXB4|E7EXB4_HUMAN,tr|A0A7I2YQ71|A0A7I2YQ71_HUMAN,tr|E7ESH4|E7ESH4_HUMAN,tr|A0A7I2V5M1|A0A7I2V5M1_HUMAN,tr|A0A7I2V5K3|A0A7I2V5K3_HUMAN,tr|A0A7I2V369|A0A7I2V369_HUMAN" 8 1802.9196 1.15 120838 18663 4 1802.917962 451.7372 "60 kDa heat shock protein, mitochondrial OS=Homo sapiens OX=9606 GN=HSPD1 PE=1 SV=2" 6.16 3132 - 801822 - - - -0.9351 - 2.646 0.402 - 107.7 1 1 1 -0.0017 17 0 0 0 3.84E+07 3.35E+07 - - - 3.0624 1 221125_WJC_METTL3_EV_vs_WT_F08.18664.18664.3 4.67E-13 23/100 K.R[166.11]PSTSQTVSTPAPVPVIESTEAIEAK[136.11].A sp|P12270|TPR_HUMAN 1 2712.4301 9.02 120839 18664 3 2712.429808 905.1506 Nucleoprotein TPR OS=Homo sapiens OX=9606 GN=TPR PE=1 SV=3 4.79 3132.2 - 472254 - - - -0.0929 - 4.672 0.697 - 514.6 1 2 0 -0.0003 26 0 0 0 4.97E+07 5.51E+06 - - - 9.8574 0.9807 221125_WJC_METTL3_EV_vs_WT_F08.18675.18675.3 0.000773 16/64 S.ANGDKEIGNIISDAMKK.V "sp|P10809|CH60_HUMAN,tr|A0A7I2V599|A0A7I2V599_HUMAN,tr|E7EXB4|E7EXB4_HUMAN,tr|A0A7I2YQ71|A0A7I2YQ71_HUMAN,tr|E7ESH4|E7ESH4_HUMAN,tr|A0A7I2V5M1|A0A7I2V5M1_HUMAN,tr|A0A7I2V5K3|A0A7I2V5K3_HUMAN,tr|A0A7I2V369|A0A7I2V369_HUMAN" 8 1802.9196 1.33 120845 18675 3 1802.919605 601.9805 "60 kDa heat shock protein, mitochondrial OS=Homo sapiens OX=9606 GN=HSPD1 PE=1 SV=2" 6.16 3133.8 - 664787 - - - -0.0239 - 2.801 0.448 - 285.7 1 1 1 0 17 0 0 0 2.76E+07 2.07E+07 - - - 6.1368 0.94 221125_WJC_METTL3_EV_vs_WT_F08.18679.18679.4 0.00464 12/138 A.HVPTLQVLRPGLVVVHAEDGTTSK.Y "sp|P30049|ATPD_HUMAN,tr|A0A087WTL3|A0A087WTL3_HUMAN" 2 2552.4075 3.69 120847 18679 4 2552.416808 639.1091 "ATP synthase subunit delta, mitochondrial OS=Homo sapiens OX=9606 GN=ATP5F1D PE=1 SV=2" 6.92 3134.3 - 303598 - - - 3.6581 - 2.348 0.421 - 50.9 1 1 0 0.0093 24 0 0 0 1.26E+07 3.41E+06 - - - 3.1618 1 221125_WJC_METTL3_EV_vs_WT_F08.18685.18685.4 9.54E-13 19/246 R.LLPC[160.03]LHSAC[160.03]SAC[160.03]LGPAAPAAANSSGDGGAAGDGTVVDC[160.03]PVC[160.03]K.Q sp|Q13263|TIF1B_HUMAN 1 4110.8326 1.04 120850 18685 4 4110.830512 1028.7154 Transcription intermediary factor 1-beta OS=Homo sapiens OX=9606 GN=TRIM28 PE=1 SV=5 4.41 3135.1 - 905217 - - - -0.5057 - 3.791 0.716 - 130.2 1 2 0 -0.0021 42 0 0 0 1.71E+07 1.64E+07 - - - 5.8385 1 221125_WJC_METTL3_EV_vs_WT_F08.18690.18690.4 1.24E-13 30/138 R.KSPTMEQAVQTASAHLPAPAAVGR.R sp|Q8ND56|LS14A_HUMAN 1 2417.2485 1.2 120854 18690 4 2417.25208 605.3194 Protein LSM14 homolog A OS=Homo sapiens OX=9606 GN=LSM14A PE=1 SV=3 8.75 3135.7 - 6.47E+06 - - - 1.4694 - 5.266 0.676 - 409.6 1 2 0 0.0036 24 0 0 0 2.25E+08 1.87E+08 - - - 5.6421 1 221125_WJC_METTL3_EV_vs_WT_F08.18694.18694.4 2.69E-12 29/186 K.TPETVVPTALELQPSTSTDRPVTSEPTSQATR.G "sp|Q14676|MDC1_HUMAN,tr|H0Y6Z8|H0Y6Z8_HUMAN" 2 3395.7056 0.35 120857 18694 4 3395.716231 849.9337 Mediator of DNA damage checkpoint protein 1 OS=Homo sapiens OX=9606 GN=MDC1 PE=1 SV=3 4.41 3136.2 - 700895 - - - 3.1239 - 4.006 0.619 - 261.8 1 2 0 0.0106 32 0 0 0 1.04E+07 2.92E+07 - - - 5.0299 1 221125_WJC_METTL3_EV_vs_WT_F08.18695.18695.3 6.11E-08 18/124 K.TPETVVPTALELQPSTSTDRPVTSEPTSQATR.G "sp|Q14676|MDC1_HUMAN,tr|H0Y6Z8|H0Y6Z8_HUMAN" 2 3395.7056 0.46 120858 18695 3 3395.701055 1132.9092 Mediator of DNA damage checkpoint protein 1 OS=Homo sapiens OX=9606 GN=MDC1 PE=1 SV=3 4.41 3136.3 - 624526 - - - -1.3452 - 2.631 0.521 - 135.6 1 2 0 -0.0046 32 0 0 0 1.59E+07 3.45E+07 - - - 6.5729 0.9995 221125_WJC_METTL3_EV_vs_WT_F08.18701.18701.3 0.000291 Oct-40 K.LKVPEWVDTVK.L "sp|P39019|RS19_HUMAN,tr|M0R140|M0R140_HUMAN,tr|M0R2L9|M0R2L9_HUMAN,tr|M0QYF7|M0QYF7_HUMAN" 4 1312.7391 1.3 120862 18701 3 1312.739514 438.587 40S ribosomal protein S19 OS=Homo sapiens OX=9606 GN=RPS19 PE=1 SV=2 6.07 3137.1 - 212974 - - - 0.3245 - 1.849 0.434 - 154.6 1 2 1 0.0004 11 0 0 0 9.35E+06 7.19E+06 - - - 5.1247 1 221125_WJC_METTL3_EV_vs_WT_F08.18712.18712.3 1.24E-05 Aug-52 K.K[136.11]GPGEVAGTVTGQK[136.11].R "sp|Q86U44|MTA70_HUMAN,tr|F5H6D8|F5H6D8_HUMAN,tr|H0YFV6|H0YFV6_HUMAN,tr|B4DTN4|B4DTN4_HUMAN" 4 1343.738 0.01 120867 18712 3 1343.738994 448.9199 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 8.59 3138.6 - 121869 - - - 0.7554 - 1.812 0.523 - 88.5 1 2 0 0.001 14 0 0 0 4.86E+04 8.38E+06 - - - 5.9504 1 221125_WJC_METTL3_EV_vs_WT_F08.18714.18714.3 4.43E-14 20/108 K.EEMSQLTGQNSGDVNVEINVAPGKDLTK.T "sp|P35527|K1C9_HUMAN,tr|K7EQQ3|K7EQQ3_HUMAN" 2 2972.4397 999 120869 18714 3 2972.451229 991.8205 "Keratin, type I cytoskeletal 9 OS=Homo sapiens OX=9606 GN=KRT9 PE=1 SV=3" 4.18 3138.9 - 346958 - - - 3.8803 - 3.915 0.733 - 216.5 1 2 1 0.0115 28 0 0 0 2.92E+07 0.00E+00 - - - 9.849 1 221125_WJC_METTL3_EV_vs_WT_F08.18718.18718.4 8.23E-10 31/138 R.K[136.11]SPTMEQAVQTASAHLPAPAAVGR[166.11].R sp|Q8ND56|LS14A_HUMAN 1 2435.271 1.22 120871 18718 4 2435.274737 609.825 Protein LSM14 homolog A OS=Homo sapiens OX=9606 GN=LSM14A PE=1 SV=3 8.75 3139.4 - 2.95E+06 - - - 1.5354 - 4.648 0.633 - 429.4 1 2 0 0.0037 24 0 0 0 2.09E+08 1.71E+08 - - - 5.2277 0.9824 221125_WJC_METTL3_EV_vs_WT_F08.18720.18720.4 0.0482 9/138 K.EVMNADDPDLQR[166.11]PDEEAIK[136.11]EITEK[136.11].T "sp|Q13573|SNW1_HUMAN,tr|G3V3A4|G3V3A4_HUMAN" 2 2810.349 1.25 120873 18720 4 2810.3562 703.5945 SNW domain-containing protein 1 OS=Homo sapiens OX=9606 GN=SNW1 PE=1 SV=1 4.01 3139.7 - 312160 - - - 2.5481 - 1.811 0.271 - 29.5 1 2 1 0.0072 24 0 0 0 1.83E+07 1.46E+07 - - - 1.7734 1 221125_WJC_METTL3_EV_vs_WT_F08.18724.18724.3 1.14E-08 27/88 K.QSK[136.11]PVTTPEEIAQVATISANGDK[136.11].E "sp|P10809|CH60_HUMAN,tr|A0A7I2V599|A0A7I2V599_HUMAN,tr|E7EXB4|E7EXB4_HUMAN,tr|A0A7I2YQ71|A0A7I2YQ71_HUMAN,tr|E7ESH4|E7ESH4_HUMAN,tr|A0A7I2V5M1|A0A7I2V5M1_HUMAN,tr|A0A7I2V5K3|A0A7I2V5K3_HUMAN,tr|A0A7I2V369|A0A7I2V369_HUMAN" 8 2399.2515 1.63 120876 18724 3 2399.251026 800.7578 "60 kDa heat shock protein, mitochondrial OS=Homo sapiens OX=9606 GN=HSPD1 PE=1 SV=2" 4.68 3140.1 - 2.02E+06 - - - -0.1909 - 4.084 0.524 - 583.5 1 2 0 -0.0005 23 0 0 0 1.82E+08 1.11E+08 - - - 7.6829 1 221125_WJC_METTL3_EV_vs_WT_F08.18736.18736.3 1.14E-07 24/88 K.QSKPVTTPEEIAQVATISANGDK.E "sp|P10809|CH60_HUMAN,tr|A0A7I2V599|A0A7I2V599_HUMAN,tr|E7EXB4|E7EXB4_HUMAN,tr|A0A7I2YQ71|A0A7I2YQ71_HUMAN,tr|E7ESH4|E7ESH4_HUMAN,tr|A0A7I2V5M1|A0A7I2V5M1_HUMAN,tr|A0A7I2V5K3|A0A7I2V5K3_HUMAN,tr|A0A7I2V369|A0A7I2V369_HUMAN" 8 2383.2231 1.63 120883 18736 3 2383.228649 795.415 "60 kDa heat shock protein, mitochondrial OS=Homo sapiens OX=9606 GN=HSPD1 PE=1 SV=2" 4.68 3141.5 - 1.93E+06 - - - 2.3351 - 4.148 0.569 - 631.6 1 2 0 0.0056 23 0 0 0 1.85E+08 1.13E+08 - - - 8.2196 1 221125_WJC_METTL3_EV_vs_WT_F08.18740.18740.4 1.11E-12 20/144 R.NVHTTDFPGNYSGYDDAWDQDR[166.11]FEK[136.11].N "sp|O15160|RPAC1_HUMAN,tr|A0A2R8YEZ4|A0A2R8YEZ4_HUMAN,tr|H0Y723|H0Y723_HUMAN,tr|E7EQB9|E7EQB9_HUMAN,tr|A0A2R8Y5D3|A0A2R8Y5D3_HUMAN,tr|A0A2R8Y8D6|A0A2R8Y8D6_HUMAN" 6 2994.2812 0.09 120886 18740 4 2994.28917 749.5776 DNA-directed RNA polymerases I and III subunit RPAC1 OS=Homo sapiens OX=9606 GN=POLR1C PE=1 SV=1 4.17 3142 - 500176 - - - 2.6738 - 3.655 0.664 - 246.6 1 2 1 0.008 25 0 0 0 7.59E+06 8.89E+07 - - - 5.4156 0.9983 221125_WJC_METTL3_EV_vs_WT_F08.18747.18747.4 0.000385 Sep-90 K.KDEKTDTLEDLFPTTK.L sp|P13010|XRCC5_HUMAN 1 1879.9415 1.03 120891 18747 4 1879.9472 470.9926 X-ray repair cross-complementing protein 5 OS=Homo sapiens OX=9606 GN=XRCC5 PE=1 SV=3 4.44 3142.9 - 191499 - - - 3.0379 - 2.007 0.41 - 69.6 1 2 1 0.0057 16 0 0 0 1.76E+07 1.71E+07 - - - 3.0385 1 221125_WJC_METTL3_EV_vs_WT_F08.18748.18748.4 9.80E-07 22/138 K.EVMNADDPDLQRPDEEAIKEITEK.T "sp|Q13573|SNW1_HUMAN,tr|G3V3A4|G3V3A4_HUMAN" 2 2784.3124 1.26 120892 18748 4 2784.315155 697.0854 SNW domain-containing protein 1 OS=Homo sapiens OX=9606 GN=SNW1 PE=1 SV=1 4.01 3143.1 - 529043 - - - 1.0006 - 3.746 0.631 - 265.4 1 2 1 0.0028 24 0 0 0 1.84E+07 1.46E+07 - - - 5.1413 1 221125_WJC_METTL3_EV_vs_WT_F08.18764.18764.3 1.37E-09 16/104 K.STEQQQAAPEPDPSTMTPQEQQQYWYR.Q "sp|P49750|YLPM1_HUMAN,tr|F8VU51|F8VU51_HUMAN" 2 3223.4153 6.14 120904 18764 3 3223.424844 1075.479 YLP motif-containing protein 1 OS=Homo sapiens OX=9606 GN=YLPM1 PE=1 SV=4 4 3145.2 - 319478 - - - 2.9698 - 3.633 0.66 - 152.6 1 2 0 0.0096 27 0 0 0 6.00E+06 9.77E+05 - - - 8.8637 1 221125_WJC_METTL3_EV_vs_WT_F08.18765.18765.3 3.68E-10 15/52 K.HTTSIFDDFSHYEK.R sp|Q9Y5A9|YTHD2_HUMAN 1 1725.7635 1.41 120905 18765 3 1725.768453 576.2618 YTH domain-containing family protein 2 OS=Homo sapiens OX=9606 GN=YTHDF2 PE=1 SV=2 5.21 3145.3 - 247149 - - - 2.8903 - 2.924 0.635 - 197.8 1 2 0 0.005 14 0 0 0 4.37E+08 3.10E+08 - - - 8.4696 1 221125_WJC_METTL3_EV_vs_WT_F08.18769.18769.3 6.47E-14 26/84 K.TKEQANAVSEAVVSSVNTVATK.T sp|O76070|SYUG_HUMAN 1 2232.1598 2.48 120907 18769 3 2232.164624 745.0605 Gamma-synuclein OS=Homo sapiens OX=9606 GN=SNCG PE=1 SV=2 5.81 3145.9 - 1.10E+06 - - - 2.1813 - 4.621 0.591 - 846.5 1 2 1 0.0049 22 0 0 0 1.03E+08 4.13E+07 - - - 8.7565 1 221125_WJC_METTL3_EV_vs_WT_F08.18770.18770.3 1.15E-10 18/52 K.HTTSIFDDFSHYEK[136.11].R sp|Q9Y5A9|YTHD2_HUMAN 1 1733.7777 1.41 120908 18770 3 1733.779333 578.9332 YTH domain-containing family protein 2 OS=Homo sapiens OX=9606 GN=YTHDF2 PE=1 SV=2 5.21 3146 - 604996 - - - 0.9621 - 3.149 0.596 - 273.5 1 2 0 0.0017 14 0 0 0 4.36E+08 3.10E+08 - - - 8.2328 1 221125_WJC_METTL3_EV_vs_WT_F08.18771.18771.4 0.000233 Sep-78 K.HTTSIFDDFSHYEK[136.11].R sp|Q9Y5A9|YTHD2_HUMAN 1 1733.7777 1.39 120909 18771 4 1733.779616 434.4517 YTH domain-containing family protein 2 OS=Homo sapiens OX=9606 GN=YTHDF2 PE=1 SV=2 5.21 3146.1 - 175402 - - - 1.1253 - 2.134 0.498 - 30.3 1 2 0 0.002 14 0 0 0 1.23E+08 8.83E+07 - - - 3.8359 0.9992 221125_WJC_METTL3_EV_vs_WT_F08.18774.18774.4 1.41E-08 21/126 K.HFSIHPDTGVITTTTPFLDREK.C sp|Q08554|DSC1_HUMAN 1 2511.2758 54.95 120910 18774 4 2511.286676 628.8262 Desmocollin-1 OS=Homo sapiens OX=9606 GN=DSC1 PE=1 SV=2 6 3146.5 - 989025 - - - 4.3356 - 3.554 0.528 - 302.4 1 2 1 0.0109 22 0 0 0 4.83E+07 8.80E+05 - - - 4.2336 0.9997 221125_WJC_METTL3_EV_vs_WT_F08.18775.18775.4 1.34E-05 16/114 K.SFPK[136.11]DDPSK[136.11]PVHLTAFLGYK[136.11].A "sp|P39023|RL3_HUMAN,tr|H7C3M2|H7C3M2_HUMAN,tr|F8WCR1|F8WCR1_HUMAN,tr|H7C422|H7C422_HUMAN" 4 2270.2162 1.15 120911 18775 4 2270.220058 568.5613 60S ribosomal protein L3 OS=Homo sapiens OX=9606 GN=RPL3 PE=1 SV=2 8.18 3146.7 - 523225 - - - 1.7192 - 2.37 0.477 - 85.2 1 2 1 0.0039 20 0 0 0 3.47E+07 3.01E+07 - - - 3.6652 1 221125_WJC_METTL3_EV_vs_WT_F08.18776.18776.4 7.54E-08 25/168 R.VAELLLLHGAEPNC[160.03]ADPATLTRPVHDAAR.E "sp|P42771|CDN2A_HUMAN,sp|P42772|CDN2B_HUMAN,tr|K7ENC6|K7ENC6_HUMAN,tr|J3QRG6|J3QRG6_HUMAN,tr|K7ES20|K7ES20_HUMAN" 5 3106.5982 2.96 120912 18776 4 3106.606206 777.6568 Cyclin-dependent kinase inhibitor 2A OS=Homo sapiens OX=9606 GN=CDKN2A PE=1 SV=2 5.31 3146.8 - 678527 - - - 2.5765 - 4.174 0.583 - 187.6 1 2 0 0.008 29 0 0 0 3.71E+07 1.25E+07 - - - 4.7386 0.9997 221125_WJC_METTL3_EV_vs_WT_F08.18778.18778.3 1.74E-05 Oct-48 R.SIFDHIKLPQASK.S "sp|Q9NYF8|BCLF1_HUMAN,tr|E9PKI6|E9PKI6_HUMAN,tr|A0A1W2PQ43|A0A1W2PQ43_HUMAN,tr|E9PK91|E9PK91_HUMAN,tr|E9PJA7|E9PJA7_HUMAN,tr|E9PK09|E9PK09_HUMAN,tr|E9PQN2|E9PQN2_HUMAN" 7 1482.8195 2.21 120914 18778 3 1482.822599 495.2804 Bcl-2-associated transcription factor 1 OS=Homo sapiens OX=9606 GN=BCLAF1 PE=1 SV=2 8.33 3147 - 264656 - - - 2.1142 - 2.012 0.533 - 92.7 1 2 1 0.0031 13 0 0 0 1.59E+07 7.20E+06 - - - 6.3771 1 221125_WJC_METTL3_EV_vs_WT_F08.18784.18784.4 1.27E-08 18/78 K.HTTSIFDDFSHYEK.R sp|Q9Y5A9|YTHD2_HUMAN 1 1725.7635 1.39 120918 18784 4 1725.765337 432.4481 YTH domain-containing family protein 2 OS=Homo sapiens OX=9606 GN=YTHDF2 PE=1 SV=2 5.21 3147.8 - 626704 - - - 1.0847 - 3.304 0.665 - 170.1 1 2 0 0.0019 14 0 0 0 1.23E+08 8.83E+07 - - - 5.4486 0.9999 221125_WJC_METTL3_EV_vs_WT_F08.18791.18791.3 2.61E-10 15/60 K.K[136.11]DEK[136.11]TDTLEDLFPTTK[136.11].L sp|P13010|XRCC5_HUMAN 1 1903.9841 0.83 120923 18791 3 1903.985813 635.6686 X-ray repair cross-complementing protein 5 OS=Homo sapiens OX=9606 GN=XRCC5 PE=1 SV=3 4.44 3148.8 - 447451 - - - 0.9055 - 3.092 0.557 - 277.8 1 2 1 0.0017 16 0 0 0 2.71E+07 3.25E+07 - - - 7.6459 0.7966 221125_WJC_METTL3_EV_vs_WT_F08.18797.18797.2 0.0846 16-Jun R.AVFPSIVGR.P "sp|Q6S8J3|POTEE_HUMAN,sp|P63261|ACTG_HUMAN,sp|P68133|ACTS_HUMAN,sp|P62736|ACTA_HUMAN,sp|P68032|ACTC_HUMAN,sp|P60709|ACTB_HUMAN,sp|P63267|ACTH_HUMAN,sp|A5A3E0|POTEF_HUMAN,sp|P0CG38|POTEI_HUMAN,tr|A0A804GS07|A0A804GS07_HUMAN,tr|I3L3I0|I3L3I0_HUMAN,tr|G5E9R0|G5E9R0_HUMAN,tr|E7EVS6|E7EVS6_HUMAN,tr|B8ZZJ2|B8ZZJ2_HUMAN,tr|J3KT65|J3KT65_HUMAN,tr|I3L3R2|I3L3R2_HUMAN,tr|K7EM38|K7EM38_HUMAN,tr|F6QUT6|F6QUT6_HUMAN,tr|C9JTX5|C9JTX5_HUMAN,tr|A0A6Q8PH58|A0A6Q8PH58_HUMAN,tr|F6UVQ4|F6UVQ4_HUMAN,tr|F8WB63|F8WB63_HUMAN,tr|I3L1U9|I3L1U9_HUMAN,tr|A0A2R8Y793|A0A2R8Y793_HUMAN,tr|I3L4N8|I3L4N8_HUMAN,tr|C9JUM1|C9JUM1_HUMAN,tr|F8WCH0|F8WCH0_HUMAN,tr|C9JZR7|C9JZR7_HUMAN,tr|C9JFL5|C9JFL5_HUMAN,tr|A0A2R8YGF8|A0A2R8YGF8_HUMAN,tr|A6NL76|A6NL76_HUMAN" 31 944.5444 12.82 120927 18797 2 944.54606 473.2795 POTE ankyrin domain family member E OS=Homo sapiens OX=9606 GN=POTEE PE=2 SV=3 9.79 3149.5 - 163066 - - - 1.8093 - 1.391 0.24 - 119.7 1 1 0 0.0017 9 0 0 0 4.46E+06 3.48E+05 - - - 1.7679 1 221125_WJC_METTL3_EV_vs_WT_F08.18801.18801.3 1.11E-06 14/68 R.NLNHSLPSDFTFQNMNSK.R sp|Q15208|STK38_HUMAN 1 2092.9636 5.25 120929 18801 3 2092.965785 698.6618 Serine\threonine-protein kinase 38 OS=Homo sapiens OX=9606 GN=STK38 PE=1 SV=1 6.74 3150 - 492156 - - - 1.0258 - 2.871 0.507 - 280.8 1 2 0 0.0021 18 0 0 0 8.85E+06 1.69E+06 - - - 6.8182 0.9978 221125_WJC_METTL3_EV_vs_WT_F08.18802.18802.3 0.00475 16/56 R.STSHK[136.11]PDEIYGMIER[166.11].L sp|Q86U44|MTA70_HUMAN 1 1779.8581 0.02 120930 18802 3 1779.850872 594.2933 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 5.42 3150.1 - 330850 - - - -4.0352 - 2.012 0.353 - 274.7 1 2 0 -0.0072 15 0 0 0 1.31E+05 7.18E+06 - - - 4.2979 0.9999 221125_WJC_METTL3_EV_vs_WT_F08.18804.18804.4 4.28E-08 19/126 K.TKEQANAVSEAVVSSVNTVATK.T sp|O76070|SYUG_HUMAN 1 2232.1598 0.39 120932 18804 4 2232.165185 559.0472 Gamma-synuclein OS=Homo sapiens OX=9606 GN=SNCG PE=1 SV=2 5.81 3150.4 - 289950 - - - 2.4326 - 3.821 0.564 - 327.1 1 2 1 0.0054 22 0 0 0 6.59E+06 1.68E+07 - - - 4.5722 0.9895 221125_WJC_METTL3_EV_vs_WT_F08.18805.18805.4 0.263 11/102 K.NVQDAIADAEQRGEHALK.D sp|P35908|K22E_HUMAN 1 1963.9712 18456.24 120933 18805 4 1963.974695 492.0001 "Keratin, type II cytoskeletal 2 epidermal OS=Homo sapiens OX=9606 GN=KRT2 PE=1 SV=2" 4.75 3150.5 - 151505 - - - 1.7964 - 1.363 0.282 - 59.7 1 2 1 0.0035 18 0 0 0 1.24E+09 6.71E+04 - - - 1.7856 0.999 221125_WJC_METTL3_EV_vs_WT_F08.18806.18806.3 0.000389 Sep-48 R.SIFDHIK[136.11]LPQASK[136.11].S "sp|Q9NYF8|BCLF1_HUMAN,tr|E9PKI6|E9PKI6_HUMAN,tr|A0A1W2PQ43|A0A1W2PQ43_HUMAN,tr|E9PK91|E9PK91_HUMAN,tr|E9PJA7|E9PJA7_HUMAN,tr|E9PK09|E9PK09_HUMAN,tr|E9PQN2|E9PQN2_HUMAN" 7 1498.8479 2.21 120934 18806 3 1498.85104 500.6232 Bcl-2-associated transcription factor 1 OS=Homo sapiens OX=9606 GN=BCLAF1 PE=1 SV=2 8.33 3150.7 - 147493 - - - 2.119 - 2.003 0.429 - 60.2 1 2 1 0.0032 13 0 0 0 1.59E+07 7.20E+06 - - - 5.2054 1 221125_WJC_METTL3_EV_vs_WT_F08.18823.18823.4 1.63E-13 25/150 R.K[136.11]FVIHPESNNLIIIETDHNAYTEATK[136.11].A sp|Q15393|SF3B3_HUMAN 1 3012.5528 1.28 120945 18823 4 3012.548709 754.1455 Splicing factor 3B subunit 3 OS=Homo sapiens OX=9606 GN=SF3B3 PE=1 SV=4 5.36 3152.9 - 759976 - - - -1.3417 - 5.108 0.663 - 537.4 1 2 0 -0.004 26 0 0 0 5.43E+07 4.25E+07 - - - 5.51 1 221125_WJC_METTL3_EV_vs_WT_F08.18824.18824.4 4.83E-09 21/168 R.VAELLLLHGAEPNC[160.03]ADPATLTR[166.11]PVHDAAR[166.11].E "sp|P42771|CDN2A_HUMAN,sp|P42772|CDN2B_HUMAN,tr|K7ENC6|K7ENC6_HUMAN,tr|J3QRG6|J3QRG6_HUMAN,tr|K7ES20|K7ES20_HUMAN" 5 3126.6147 2.96 120946 18824 4 3126.614522 782.661 Cyclin-dependent kinase inhibitor 2A OS=Homo sapiens OX=9606 GN=CDKN2A PE=1 SV=2 5.31 3153 - 599732 - - - -0.0704 - 3.326 0.546 - 137.2 1 2 0 -0.0002 29 0 0 0 3.71E+07 1.25E+07 - - - 4.3487 0.9919 221125_WJC_METTL3_EV_vs_WT_F08.18825.18825.4 0.0144 10/108 K.EAEKPAVPETAGIKFPDFK.S sp|Q9NPF5|DMAP1_HUMAN 1 2073.0783 1.38 120947 18825 4 2073.08154 519.2768 DNA methyltransferase 1-associated protein 1 OS=Homo sapiens OX=9606 GN=DMAP1 PE=1 SV=1 4.87 3153.2 - 445819 - - - 1.5836 - 1.906 0.275 - 33.3 1 2 1 0.0033 19 0 0 0 1.07E+07 7.71E+06 - - - 1.8369 0.9908 221125_WJC_METTL3_EV_vs_WT_F08.18827.18827.4 0.112 9/108 K.EAEK[136.11]PAVPETAGIK[136.11]FPDFK[136.11].S sp|Q9NPF5|DMAP1_HUMAN 1 2097.1209 1.38 120949 18827 4 2097.122638 525.2875 DNA methyltransferase 1-associated protein 1 OS=Homo sapiens OX=9606 GN=DMAP1 PE=1 SV=1 4.87 3153.4 - 177971 - - - 0.8493 - 1.962 0.259 - 44 1 2 1 0.0018 19 0 0 0 1.07E+07 7.71E+06 - - - 1.7078 1 221125_WJC_METTL3_EV_vs_WT_F08.18833.18833.3 9.89E-09 18/68 K.NVQDAIADAEQRGEHALK.D sp|P35908|K22E_HUMAN 1 1963.9712 999 120953 18833 3 1963.972607 655.6643 "Keratin, type II cytoskeletal 2 epidermal OS=Homo sapiens OX=9606 GN=KRT2 PE=1 SV=2" 4.75 3154.3 - 1.13E+06 - - - 0.7332 - 3.209 0.598 - 294.3 1 2 1 0.0014 18 0 0 0 6.95E+08 0.00E+00 - - - 8.1101 1 221125_WJC_METTL3_EV_vs_WT_F08.18836.18836.4 1.04E-08 19/150 R.KFVIHPESNNLIIIETDHNAYTEATK.A sp|Q15393|SF3B3_HUMAN 1 2996.5244 1.28 120954 18836 4 2996.526212 750.1384 Splicing factor 3B subunit 3 OS=Homo sapiens OX=9606 GN=SF3B3 PE=1 SV=4 5.36 3154.6 - 1.59E+06 - - - 0.6211 - 3.933 0.57 - 186.7 1 2 0 0.0019 26 0 0 0 5.43E+07 4.25E+07 - - - 4.6187 1 221125_WJC_METTL3_EV_vs_WT_F08.18840.18840.3 1.79E-11 23/108 K.IQIASESSGIPERPC[160.03]VLTGTPESIEQAK.R sp|Q96I24|FUBP3_HUMAN 1 2996.5125 2.25 120958 18840 3 2996.513225 999.8448 Far upstream element-binding protein 3 OS=Homo sapiens OX=9606 GN=FUBP3 PE=1 SV=2 4.49 3155.2 - 519356 - - - 0.2533 - 3.809 0.623 - 335.7 1 2 0 0.0008 28 0 0 0 2.57E+07 1.14E+07 - - - 8.5624 0.9839 221125_WJC_METTL3_EV_vs_WT_F08.18841.18841.2 0.00183 14-Jul F.DDFSHYEK.R sp|Q9Y5A9|YTHD2_HUMAN 1 1039.4247 1.42 120959 18841 2 1039.424728 520.7196 YTH domain-containing family protein 2 OS=Homo sapiens OX=9606 GN=YTHDF2 PE=1 SV=2 4.54 3155.3 - 493783 - - - 0.0366 - 1.557 0.449 - 176.1 1 1 0 0 8 0 0 0 8.54E+06 6.02E+06 - - - 3.6926 1 221125_WJC_METTL3_EV_vs_WT_F08.18852.18852.3 3.22E-08 19/108 K.IQIASESSGIPER[166.11]PC[160.03]VLTGTPESIEQAK[136.11].R sp|Q96I24|FUBP3_HUMAN 1 3014.5349 2.24 120966 18852 3 3014.534539 1005.8523 Far upstream element-binding protein 3 OS=Homo sapiens OX=9606 GN=FUBP3 PE=1 SV=2 4.49 3156.7 - 455687 - - - -0.1317 - 3.166 0.578 - 208.7 1 2 0 -0.0004 28 0 0 0 2.56E+07 1.14E+07 - - - 7.6354 1 221125_WJC_METTL3_EV_vs_WT_F08.18859.18859.4 9.77E-10 24/186 K.LGGEAAHLPHLRPLPESQPSSSPLLQTAPGVK.G "sp|Q9Y618|NCOR2_HUMAN,tr|C9J7T7|C9J7T7_HUMAN,tr|C9JE98|C9JE98_HUMAN,tr|C9J0Q5|C9J0Q5_HUMAN,tr|A0A384DVL6|A0A384DVL6_HUMAN" 5 3283.7677 5.58 120971 18859 4 3283.770843 821.9492 Nuclear receptor corepressor 2 OS=Homo sapiens OX=9606 GN=NCOR2 PE=1 SV=3 6.92 3157.6 - 502847 - - - 0.9541 - 4.014 0.594 - 224 1 2 0 0.0031 32 0 0 0 1.60E+07 2.87E+06 - - - 4.8149 1 221125_WJC_METTL3_EV_vs_WT_F08.18864.18864.4 0.000146 13/84 K.LSTDDLNSLIAHAHR.R "sp|Q16891|MIC60_HUMAN,tr|B9A067|B9A067_HUMAN,tr|C9J406|C9J406_HUMAN,tr|H7C463|H7C463_HUMAN" 4 1661.8485 1.6 120973 18864 4 1661.846475 416.4694 MICOS complex subunit MIC60 OS=Homo sapiens OX=9606 GN=IMMT PE=1 SV=1 5.98 3158.4 - 314801 - - - -1.2378 - 2.724 0.492 - 202.6 1 2 0 -0.0021 15 0 0 0 8.04E+06 5.03E+06 - - - 3.8664 0.9976 221125_WJC_METTL3_EV_vs_WT_F08.18865.18865.4 0.000231 9/108 R.DK[136.11]VAGHSLGYGFVNYVTAK[136.11].D "sp|Q15717|ELAV1_HUMAN,tr|M0QZR9|M0QZR9_HUMAN" 2 2041.0604 1.59 120974 18865 4 2041.060945 511.2724 ELAV-like protein 1 OS=Homo sapiens OX=9606 GN=ELAVL1 PE=1 SV=2 8.44 3158.5 - 242483 - - - 0.2788 - 2.077 0.321 - 73.4 1 2 1 0.0006 19 0 0 0 7.32E+06 4.61E+06 - - - 2.2671 0.9982 221125_WJC_METTL3_EV_vs_WT_F08.18867.18867.4 0.0266 13/84 K.LSTDDLNSLIAHAHR[166.11].R "sp|Q16891|MIC60_HUMAN,tr|B9A067|B9A067_HUMAN,tr|C9J406|C9J406_HUMAN,tr|H7C463|H7C463_HUMAN" 4 1671.8568 1.6 120976 18867 4 1671.851579 418.9715 MICOS complex subunit MIC60 OS=Homo sapiens OX=9606 GN=IMMT PE=1 SV=1 5.98 3158.7 - 230876 - - - -3.1241 - 2.4 0.319 - 125.9 1 2 0 -0.0052 15 0 0 0 8.06E+06 5.03E+06 - - - 2.3144 0.9926 221125_WJC_METTL3_EV_vs_WT_F08.18876.18876.2 0.00126 18-Sep K.PDEIYGMIER[166.11].L sp|Q86U44|MTA70_HUMAN 1 1231.5782 0.05 120982 18876 2 1231.577908 616.7964 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 4.14 3159.8 - 497327 - - - -0.2728 - 2.116 0.496 - 314.1 1 1 0 -0.0003 10 0 0 0 6.29E+05 1.30E+07 - - - 4.7965 1 221125_WJC_METTL3_EV_vs_WT_F08.18881.18881.3 2.16E-18 22/124 K.TPEPVVPTAPELQPSTSTDQPVTSEPTSQVTR.G "sp|Q14676|MDC1_HUMAN,tr|H0Y6Z8|H0Y6Z8_HUMAN" 2 3375.6682 1.94 120984 18881 3 3375.670193 1126.23 Mediator of DNA damage checkpoint protein 1 OS=Homo sapiens OX=9606 GN=MDC1 PE=1 SV=3 4 3160.4 - 640265 - - - 0.5978 - 4.451 0.723 - 342 1 2 0 0.002 32 0 0 0 1.94E+07 1.00E+07 - - - 10.0353 0.9576 221125_WJC_METTL3_EV_vs_WT_F08.18912.18912.3 9.46E-06 16/60 V.QDAIADAEQRGEHALK.D sp|P35908|K22E_HUMAN 1 1750.8598 999 121001 18912 3 1750.864109 584.6272 "Keratin, type II cytoskeletal 2 epidermal OS=Homo sapiens OX=9606 GN=KRT2 PE=1 SV=2" 4.75 3164.2 - 633555 - - - 2.4468 - 2.967 0.447 - 344.1 1 1 1 0.0043 16 0 0 0 1.55E+07 0.00E+00 - - - 6.3129 1 221125_WJC_METTL3_EV_vs_WT_F08.18918.18918.4 1.95E-05 14/120 K.SWQGVTIYFSGHETPGEGEHK.L "sp|Q8IZH2|XRN1_HUMAN,tr|C9JCZ8|C9JCZ8_HUMAN" 2 2345.0713 1.14 121004 18918 4 2345.067125 587.2751 5'-3' exoribonuclease 1 OS=Homo sapiens OX=9606 GN=XRN1 PE=1 SV=1 5.31 3164.9 - 559884 - - - -1.7697 - 3.036 0.56 - 118.6 1 2 0 -0.0041 21 0 0 0 1.39E+07 1.22E+07 - - - 4.4663 0.984 221125_WJC_METTL3_EV_vs_WT_F08.18923.18923.4 0.000785 12/168 K.ELAEQLGLSTGEKEKLPGELEPVQATQNK.T "sp|O75821|EIF3G_HUMAN,tr|K7ER90|K7ER90_HUMAN,tr|K7EL20|K7EL20_HUMAN" 3 3135.6299 1.17 121007 18923 4 3135.627736 784.9148 Eukaryotic translation initiation factor 3 subunit G OS=Homo sapiens OX=9606 GN=EIF3G PE=1 SV=2 4.48 3165.6 - 651333 - - - -0.7026 - 2.445 0.229 - 46.5 1 2 2 -0.0022 29 0 0 0 4.75E+07 4.05E+07 - - - 1.4941 1 221125_WJC_METTL3_EV_vs_WT_F08.18934.18934.2 2.48E-11 14/34 K.NVQDAIADAEQRGEHALK.D sp|P35908|K22E_HUMAN 1 1963.9712 999 121011 18934 2 1963.970876 982.9929 "Keratin, type II cytoskeletal 2 epidermal OS=Homo sapiens OX=9606 GN=KRT2 PE=1 SV=2" 4.75 3167 - 338808 - - - -0.1482 - 3.052 0.674 - 324.4 1 2 1 -0.0003 18 0 0 0 6.33E+06 0.00E+00 - - - 6.7623 1 221125_WJC_METTL3_EV_vs_WT_F08.18937.18937.4 1.59E-09 15/156 V.SSDFNSDTHSSTFDAGAGIALNDHFVK.L "sp|P04406|G3P_HUMAN,tr|E7EUT5|E7EUT5_HUMAN" 2 2839.2685 0.71 121013 18937 4 2839.267014 710.8244 Glyceraldehyde-3-phosphate dehydrogenase OS=Homo sapiens OX=9606 GN=GAPDH PE=1 SV=3 4.54 3167.4 - 894229 - - - -0.5343 - 3.025 0.64 - 85 1 1 0 -0.0015 27 0 0 0 3.63E+07 5.12E+07 - - - 5.1425 0.957 221125_WJC_METTL3_EV_vs_WT_F08.18938.18938.3 6.21E-05 11/108 R.GSDIK[136.11]DLTVC[160.03]EPPK[136.11]PQC[160.03]SLPQDPAIVQS.S "sp|Q8ND56|LS14A_HUMAN,tr|I3L4Q1|I3L4Q1_HUMAN,tr|A0A140TA76|A0A140TA76_HUMAN,tr|K7EMZ9|K7EMZ9_HUMAN" 4 3094.5286 1.34 121014 18938 3 3094.530975 1032.5168 Protein LSM14 homolog A OS=Homo sapiens OX=9606 GN=LSM14A PE=1 SV=3 4.23 3167.5 - 596764 - - - 0.7717 - 2.318 0.43 - 66.9 1 1 1 0.0024 28 0 0 0 2.82E+07 2.11E+07 - - - 5.2676 0.9998 221125_WJC_METTL3_EV_vs_WT_F08.18941.18941.4 1.56E-06 14/114 R.GRVNFDDYTVNLGGLKDHIK.E "sp|Q06210|GFPT1_HUMAN,tr|A0A6I8PRN4|A0A6I8PRN4_HUMAN,tr|A0A6I8PTT9|A0A6I8PTT9_HUMAN" 3 2260.16 1.43 121015 18941 4 2260.161397 566.0473 Glutamine--fructose-6-phosphate aminotransferase [isomerizing] 1 OS=Homo sapiens OX=9606 GN=GFPT1 PE=1 SV=3 6.75 3168.1 - 568540 - - - 0.6048 - 2.517 0.475 - 153.5 1 2 2 0.0014 20 0 0 0 6.80E+06 4.75E+06 - - - 3.6686 0.861 221125_WJC_METTL3_EV_vs_WT_F08.18954.18954.4 2.91E-08 19/132 R.GQHVTGSPFQFTVGPLGEGGAHK[136.11].V "sp|O75369|FLNB_HUMAN,tr|E7EN95|E7EN95_HUMAN,tr|A0A804HK76|A0A804HK76_HUMAN,tr|H7C5L4|H7C5L4_HUMAN,tr|A0A804HL72|A0A804HL72_HUMAN" 5 2315.1538 0.45 121024 18954 4 2318.158858 579.7957 Filamin-B OS=Homo sapiens OX=9606 GN=FLNB PE=1 SV=2 6.92 3169.6 - 560755 - - - 1297.9824 - 3.955 0.551 - 326.7 1 2 0 3.005 23 0 0 0 1.77E+07 3.95E+07 - - - 3.635 0.9999 221125_WJC_METTL3_EV_vs_WT_F08.18958.18958.4 6.48E-08 18/114 K.TSAK[136.11]EEDAFHFVSYVPVNGR[166.11].L "sp|Q9Y5K5|UCHL5_HUMAN,tr|H0Y4E0|H0Y4E0_HUMAN,tr|Q5LJA9|Q5LJA9_HUMAN,tr|H0Y6Y4|H0Y6Y4_HUMAN,tr|Q5LJB0|Q5LJB0_HUMAN,tr|Q5LJA5|Q5LJA5_HUMAN" 6 2270.1087 1.57 121025 18958 4 2270.107419 568.5344 Ubiquitin carboxyl-terminal hydrolase isozyme L5 OS=Homo sapiens OX=9606 GN=UCHL5 PE=1 SV=3 5.41 3170.2 - 683799 - - - -0.5493 - 2.457 0.526 - 128.7 1 2 1 -0.0012 20 0 0 0 1.97E+08 1.26E+08 - - - 4.1045 1 221125_WJC_METTL3_EV_vs_WT_F08.18961.18961.4 3.02E-07 17/132 R.GQHVTGSPFQFTVGPLGEGGAHK.V "sp|O75369|FLNB_HUMAN,tr|E7EN95|E7EN95_HUMAN,tr|A0A804HK76|A0A804HK76_HUMAN,tr|H7C5L4|H7C5L4_HUMAN,tr|A0A804HL72|A0A804HL72_HUMAN" 5 2307.1396 0.45 121027 18961 4 2307.137827 577.7922 Filamin-B OS=Homo sapiens OX=9606 GN=FLNB PE=1 SV=2 6.92 3170.6 - 676190 - - - -0.7811 - 3.257 0.467 - 111 1 2 0 -0.0018 23 0 0 0 1.77E+07 3.90E+07 - - - 3.6728 1 221125_WJC_METTL3_EV_vs_WT_F08.18966.18966.3 8.77E-12 24/80 R.QVQSLTC[160.03]EVDALK[136.11]GTNESLER[166.11].Q "sp|P08670|VIME_HUMAN,tr|B0YJC5|B0YJC5_HUMAN,tr|B0YJC4|B0YJC4_HUMAN" 3 2394.1816 1.19 121030 18966 3 2394.184138 799.0678 Vimentin OS=Homo sapiens OX=9606 GN=VIM PE=1 SV=4 4.41 3171.2 - 827791 - - - 1.0709 - 4.401 0.632 - 673.5 1 2 1 0.0026 21 0 0 0 2.59E+07 2.17E+07 - - - 9.1381 0.9761 221125_WJC_METTL3_EV_vs_WT_F08.18967.18967.3 5.55E-08 19/108 R.GSDIKDLTVC[160.03]EPPKPQC[160.03]SLPQDPAIVQS.S "sp|Q8ND56|LS14A_HUMAN,tr|I3L4Q1|I3L4Q1_HUMAN,tr|A0A140TA76|A0A140TA76_HUMAN,tr|K7EMZ9|K7EMZ9_HUMAN" 4 3078.5002 1.34 121031 18967 3 3078.507851 1027.174 Protein LSM14 homolog A OS=Homo sapiens OX=9606 GN=LSM14A PE=1 SV=3 4.23 3171.3 - 535595 - - - 2.4895 - 2.759 0.563 - 251.2 1 1 1 0.0077 28 0 0 0 2.82E+07 2.11E+07 - - - 7.1496 0.9999 221125_WJC_METTL3_EV_vs_WT_F08.18971.18971.4 4.94E-08 18/168 K.ELAEQLGLSTGEK[136.11]EK[136.11]LPGELEPVQATQNK[136.11].T "sp|O75821|EIF3G_HUMAN,tr|K7ER90|K7ER90_HUMAN,tr|K7EL20|K7EL20_HUMAN" 3 3159.6725 1.17 121033 18971 4 3159.670974 790.9254 Eukaryotic translation initiation factor 3 subunit G OS=Homo sapiens OX=9606 GN=EIF3G PE=1 SV=2 4.48 3171.9 - 1.61E+06 - - - -0.4953 - 3.565 0.501 - 115.6 1 2 2 -0.0016 29 0 0 0 4.75E+07 4.05E+07 - - - 3.978 1 221125_WJC_METTL3_EV_vs_WT_F08.18973.18973.3 1.14E-13 21/76 K.TSAKEEDAFHFVSYVPVNGR.L "sp|Q9Y5K5|UCHL5_HUMAN,tr|H0Y4E0|H0Y4E0_HUMAN,tr|Q5LJA9|Q5LJA9_HUMAN,tr|H0Y6Y4|H0Y6Y4_HUMAN,tr|Q5LJB0|Q5LJB0_HUMAN,tr|Q5LJA5|Q5LJA5_HUMAN" 6 2252.0862 1.55 121035 18973 3 2252.088914 751.7027 Ubiquitin carboxyl-terminal hydrolase isozyme L5 OS=Homo sapiens OX=9606 GN=UCHL5 PE=1 SV=3 5.41 3172.1 - 1.03E+06 - - - 1.2069 - 3.995 0.698 - 481.4 1 2 1 0.0027 20 0 0 0 7.89E+07 5.10E+07 - - - 9.6814 1 221125_WJC_METTL3_EV_vs_WT_F08.18977.18977.4 1.61E-14 32/186 K.IEHTYTGGVDSDLGEAMSDC[160.03]DPDGPLMC[160.03]HTTK.M sp|Q15029|U5S1_HUMAN 1 3508.4527 2.12 121037 18977 4 3508.459827 878.1205 116 kDa U5 small nuclear ribonucleoprotein component OS=Homo sapiens OX=9606 GN=EFTUD2 PE=1 SV=1 4.08 3172.6 - 903204 - - - 2.0254 - 5.964 0.798 - 641.5 1 2 0 0.0071 32 0 0 0 1.94E+07 9.13E+06 - - - 6.709 0.9998 221125_WJC_METTL3_EV_vs_WT_F08.18979.18979.4 1.93E-05 19/114 K.TSAKEEDAFHFVSYVPVNGR.L "sp|Q9Y5K5|UCHL5_HUMAN,tr|H0Y4E0|H0Y4E0_HUMAN,tr|Q5LJA9|Q5LJA9_HUMAN,tr|H0Y6Y4|H0Y6Y4_HUMAN,tr|Q5LJB0|Q5LJB0_HUMAN,tr|Q5LJA5|Q5LJA5_HUMAN" 6 2252.0862 1.57 121038 18979 4 2252.089313 564.0288 Ubiquitin carboxyl-terminal hydrolase isozyme L5 OS=Homo sapiens OX=9606 GN=UCHL5 PE=1 SV=3 5.41 3172.9 - 4.06E+06 - - - 1.3841 - 2.203 0.509 - 200.9 1 2 1 0.0031 20 0 0 0 1.94E+08 1.24E+08 - - - 3.9195 1 221125_WJC_METTL3_EV_vs_WT_F08.18980.18980.3 4.94E-11 29/80 R.QVQSLTC[160.03]EVDALKGTNESLER.Q "sp|P08670|VIME_HUMAN,tr|B0YJC5|B0YJC5_HUMAN,tr|B0YJC4|B0YJC4_HUMAN" 3 2376.1591 1.19 121039 18980 3 2376.160631 793.0603 Vimentin OS=Homo sapiens OX=9606 GN=VIM PE=1 SV=4 4.41 3173 - 1.27E+06 - - - 0.6426 - 4.625 0.601 - 1107.2 1 2 1 0.0015 21 0 0 0 2.59E+07 2.17E+07 - - - 8.9118 0.9929 221125_WJC_METTL3_EV_vs_WT_F08.18982.18982.4 0.0346 9/144 R.SRPPEERPPGLPLPPPPPSSSAVFR.L sp|P48634|PRC2A_HUMAN 1 2663.4184 4.44 121041 18982 4 2663.415679 666.8619 Protein PRRC2A OS=Homo sapiens OX=9606 GN=PRRC2A PE=1 SV=3 9.23 3173.3 - 413127 - - - -1.0104 - 1.897 0.214 - 30.2 1 2 0 -0.0027 25 0 0 0 5.78E+06 1.30E+06 - - - 1.2916 1 221125_WJC_METTL3_EV_vs_WT_F08.18999.18999.3 1.28E-13 28/76 K.TSAK[136.11]EEDAFHFVSYVPVNGR[166.11].L "sp|Q9Y5K5|UCHL5_HUMAN,tr|H0Y4E0|H0Y4E0_HUMAN,tr|Q5LJA9|Q5LJA9_HUMAN,tr|H0Y6Y4|H0Y6Y4_HUMAN,tr|Q5LJB0|Q5LJB0_HUMAN,tr|Q5LJA5|Q5LJA5_HUMAN" 6 2270.1087 1.55 121051 18999 3 2270.111505 757.7102 Ubiquitin carboxyl-terminal hydrolase isozyme L5 OS=Homo sapiens OX=9606 GN=UCHL5 PE=1 SV=3 5.41 3175.5 - 2.24E+06 - - - 1.2506 - 4.019 0.697 - 1034.3 1 2 1 0.0028 20 0 0 0 7.91E+07 5.10E+07 - - - 9.6848 0.9994 221125_WJC_METTL3_EV_vs_WT_F08.19005.19005.3 4.28E-05 Sep-52 K.K[136.11]GPGEVAGTVTGQK[136.11].R "sp|Q86U44|MTA70_HUMAN,tr|F5H6D8|F5H6D8_HUMAN,tr|H0YFV6|H0YFV6_HUMAN,tr|B4DTN4|B4DTN4_HUMAN" 4 1343.738 0.001 121054 19005 3 1343.732595 448.9199 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 8.59 3176.3 - 180761 - - - -4.0067 - 1.814 0.475 - 77 1 2 0 -0.0054 14 0 0 0 0.00E+00 5.30E+06 - - - 5.4169 0.9999 221125_WJC_METTL3_EV_vs_WT_F08.19007.19007.4 4.45E-07 24/174 R.RGEESSGHFLVAATGTAAGGGGGLILASPK.L "tr|F5H433|F5H433_HUMAN,tr|F5H1G6|F5H1G6_HUMAN" 2 2767.4253 1.88 121055 19007 4 2767.43439 692.8636 Sal-like protein 2 OS=Homo sapiens OX=9606 GN=SALL2 PE=1 SV=3 6.76 3176.5 - 572369 - - - 3.2825 - 4.289 0.578 - 409.1 1 2 0 0.0091 30 0 0 0 1.47E+07 7.81E+06 - - - 4.7 0.9994 221125_WJC_METTL3_EV_vs_WT_F08.19008.19008.4 2.93E-08 17/120 K.EYRPHLVDQGAMLLNVSGHVK.E "sp|P22735|TGM1_HUMAN,tr|H0YMQ8|H0YMQ8_HUMAN" 2 2362.2216 0.85 121056 19008 4 2362.234348 591.5627 Protein-glutamine gamma-glutamyltransferase K OS=Homo sapiens OX=9606 GN=TGM1 PE=1 SV=4 7.01 3176.7 - 485844 - - - 5.4034 - 3.259 0.496 - 176.2 1 2 0 0.0128 21 0 0 0 1.59E+07 1.86E+07 - - - 3.9303 0.9946 221125_WJC_METTL3_EV_vs_WT_F08.19010.19010.4 0.0447 13/138 K.KSPLALLAQTC[160.03]SQIGKPDPPPSSK.L sp|Q9H7S9|ZN703_HUMAN 1 2519.3418 2.19 121058 19010 4 2519.348283 630.8427 Zinc finger protein 703 OS=Homo sapiens OX=9606 GN=ZNF703 PE=1 SV=1 9.2 3176.9 - 396774 - - - 2.5892 - 1.982 0.26 - 53.8 1 2 0 0.0065 24 0 0 0 8.14E+07 3.72E+07 - - - 1.7068 0.9991 221125_WJC_METTL3_EV_vs_WT_F08.19011.19011.4 0.00126 9/126 R.SLSEINKPNFYNNDFDDDFSHR.S "sp|Q5QJE6|TDIF2_HUMAN,tr|J3KP30|J3KP30_HUMAN" 2 2673.1732 20.74 121059 19011 4 2673.184071 669.3006 Deoxynucleotidyltransferase terminal-interacting protein 2 OS=Homo sapiens OX=9606 GN=DNTTIP2 PE=1 SV=2 4.35 3177.1 - 276023 - - - 4.0764 - 2.054 0.41 - 52.5 1 2 0 0.0109 22 0 0 0 4.33E+06 2.09E+05 - - - 3.0271 0.9484 221125_WJC_METTL3_EV_vs_WT_F08.19014.19014.4 0.0643 7/138 K.KSPLALLAQTC[160.03]SQIGKPDPSPSSK.L sp|Q96F45|ZN503_HUMAN 1 2509.321 2.12 121061 19014 4 2509.323809 628.3375 Zinc finger protein 503 OS=Homo sapiens OX=9606 GN=ZNF503 PE=1 SV=1 9.2 3177.4 - 221409 - - - 1.1099 - 1.767 0.138 - 24.9 1 2 0 0.0028 24 0 0 0 6.57E+06 3.10E+06 - - - 0.6091 0.9988 221125_WJC_METTL3_EV_vs_WT_F08.19017.19017.4 0.0186 12/114 K.QDSSPHLTSQR[166.11]PVDMVQLLK[136.11].K sp|Q96T58|MINT_HUMAN 1 2296.1964 1.02 121063 19017 4 2296.196715 575.0564 Msx2-interacting protein OS=Homo sapiens OX=9606 GN=SPEN PE=1 SV=1 6.75 3177.8 - 533721 - - - 0.1215 - 2.031 0.289 - 105.2 1 2 0 0.0003 20 0 0 0 9.98E+06 9.83E+06 - - - 1.9783 1 221125_WJC_METTL3_EV_vs_WT_F08.19021.19021.4 3.77E-11 22/174 R.R[166.11]GEESSGHFLVAATGTAAGGGGGLILASPK[136.11].L "tr|F5H433|F5H433_HUMAN,tr|F5H1G6|F5H1G6_HUMAN" 2 2785.4478 1.88 121065 19021 4 2785.452908 697.3692 Sal-like protein 2 OS=Homo sapiens OX=9606 GN=SALL2 PE=1 SV=3 6.76 3178.3 - 467137 - - - 1.8424 - 4.221 0.656 - 316.3 1 2 0 0.0051 30 0 0 0 1.47E+07 7.81E+06 - - - 5.3751 1 221125_WJC_METTL3_EV_vs_WT_F08.19022.19022.3 2.30E-14 20/96 R.SLDNK[136.11]GDTDGEDQVC[160.03]VSEISIVTNR[166.11].G sp|Q6ULP2|AFTIN_HUMAN 1 2768.289 1.67 121066 19022 3 2768.297413 923.7703 Aftiphilin OS=Homo sapiens OX=9606 GN=AFTPH PE=1 SV=3 3.96 3178.5 - 403008 - - - 3.0564 - 3.624 0.733 - 295.8 1 2 1 0.0085 25 0 0 0 1.32E+07 7.92E+06 - - - 9.6721 0.9999 221125_WJC_METTL3_EV_vs_WT_F08.19028.19028.4 4.39E-09 19/108 K.VTEGLVDVILYHQPDDK[136.11]K[136.11]K[136.11].N "sp|O43390|HNRPR_HUMAN,tr|B4DT28|B4DT28_HUMAN,tr|A0A6Q8PHG0|A0A6Q8PHG0_HUMAN,tr|A0A6Q8PH31|A0A6Q8PH31_HUMAN,tr|A0A6Q8PEX7|A0A6Q8PEX7_HUMAN" 5 2220.2216 1.6 121070 19028 4 2220.222882 556.0627 Heterogeneous nuclear ribonucleoprotein R OS=Homo sapiens OX=9606 GN=HNRNPR PE=1 SV=1 5.43 3179.3 - 483891 - - - 0.5621 - 4.121 0.525 - 319 1 2 1 0.0012 19 0 0 0 2.94E+07 1.83E+07 - - - 4.2743 0.9961 221125_WJC_METTL3_EV_vs_WT_F08.19031.19031.4 4.87E-06 12/150 S.SDFNSDTHSSTFDAGAGIALNDHFVK.L "sp|P04406|G3P_HUMAN,tr|E7EUT5|E7EUT5_HUMAN" 2 2752.2365 0.68 121073 19031 4 2752.241479 689.0664 Glyceraldehyde-3-phosphate dehydrogenase OS=Homo sapiens OX=9606 GN=GAPDH PE=1 SV=3 4.54 3179.6 - 377412 - - - 1.8083 - 2.245 0.549 - 60.8 1 1 0 0.005 26 0 0 0 3.92E+06 5.72E+06 - - - 4.2582 0.9996 221125_WJC_METTL3_EV_vs_WT_F08.19032.19032.4 2.23E-06 19/180 K.QVYIPTYTKPNPNQIISVGSKPGMNGAGFQK.G sp|O94776|MTA2_HUMAN 1 3333.718 0.59 121074 19032 4 3333.731908 834.4368 Metastasis-associated protein MTA2 OS=Homo sapiens OX=9606 GN=MTA2 PE=1 SV=1 9.83 3179.8 - 353891 - - - 4.177 - 3.354 0.47 - 133.7 1 2 0 0.0139 31 0 0 0 5.57E+06 9.48E+06 - - - 3.6808 1 221125_WJC_METTL3_EV_vs_WT_F08.19038.19038.3 2.14E-06 15/80 K.TATQTGHTLLEDYQIVDNSQR.E sp|Q8N0X7|SPART_HUMAN 1 2389.151 3.12 121078 19038 3 2389.149309 797.3909 Spartin OS=Homo sapiens OX=9606 GN=SPART PE=1 SV=1 4.53 3180.5 - 521689 - - - -0.7002 - 3.415 0.515 - 214.3 1 2 0 -0.0017 21 0 0 0 1.22E+07 3.92E+06 - - - 7.2258 0.9987 221125_WJC_METTL3_EV_vs_WT_F08.19039.19039.3 1.09E-08 13/108 L.TSFGTETSNSGTLPQSSAVGSAFTQDTR[166.11].S "sp|Q8ND56|LS14A_HUMAN,tr|A0A140TA76|A0A140TA76_HUMAN,tr|K7EMZ9|K7EMZ9_HUMAN" 3 2843.3085 1.03 121079 19039 3 2843.312093 948.7768 Protein LSM14 homolog A OS=Homo sapiens OX=9606 GN=LSM14A PE=1 SV=3 4.37 3180.6 - 304046 - - - 1.2654 - 3.121 0.643 - 113 1 1 0 0.0036 28 0 0 0 1.09E+07 1.06E+07 - - - 8.3263 0.9998 221125_WJC_METTL3_EV_vs_WT_F08.19044.19044.4 8.04E-08 21/108 K.VTEGLVDVILYHQPDDKKK.N "sp|O43390|HNRPR_HUMAN,tr|B4DT28|B4DT28_HUMAN,tr|A0A6Q8PHG0|A0A6Q8PHG0_HUMAN,tr|A0A6Q8PH31|A0A6Q8PH31_HUMAN,tr|A0A6Q8PEX7|A0A6Q8PEX7_HUMAN" 5 2196.179 1.58 121082 19044 4 2196.18577 550.052 Heterogeneous nuclear ribonucleoprotein R OS=Homo sapiens OX=9606 GN=HNRNPR PE=1 SV=1 5.43 3181.3 - 1.07E+06 - - - 3.0671 - 3.906 0.56 - 350.3 1 2 1 0.0067 19 0 0 0 2.90E+07 1.83E+07 - - - 4.5593 1 221125_WJC_METTL3_EV_vs_WT_F08.19047.19047.3 9.67E-09 14/112 K.GTDDLNPVTSTPAK[136.11]PSSPPPEFSFNTPGK[136.11].N "sp|Q6NXT4|ZNT6_HUMAN,tr|B5MCR8|B5MCR8_HUMAN" 2 3000.4687 1.26 121085 19047 3 3000.475365 1001.1635 Zinc transporter 6 OS=Homo sapiens OX=9606 GN=SLC30A6 PE=1 SV=2 4.56 3181.7 - 225931 - - - 2.2057 - 2.933 0.649 - 138.3 1 2 0 0.0066 29 0 0 0 4.55E+06 3.60E+06 - - - 8.2494 1 221125_WJC_METTL3_EV_vs_WT_F08.19052.19052.3 1.09E-13 23/96 R.SLDNKGDTDGEDQVC[160.03]VSEISIVTNR.G sp|Q6ULP2|AFTIN_HUMAN 1 2750.2665 1.7 121088 19052 3 2750.271948 917.7628 Aftiphilin OS=Homo sapiens OX=9606 GN=AFTPH PE=1 SV=3 3.96 3182.4 - 554310 - - - 1.9874 - 3.77 0.75 - 552.2 1 2 1 0.0055 25 0 0 0 1.35E+07 7.92E+06 - - - 9.9534 1 221125_WJC_METTL3_EV_vs_WT_F08.19054.19054.3 8.12E-05 23/108 L.TSFGTETSNSGTLPQSSAVGSAFTQDTR.S "sp|Q8ND56|LS14A_HUMAN,tr|A0A140TA76|A0A140TA76_HUMAN,tr|K7EMZ9|K7EMZ9_HUMAN" 3 2833.3002 1.03 121090 19054 3 2833.309467 945.4407 Protein LSM14 homolog A OS=Homo sapiens OX=9606 GN=LSM14A PE=1 SV=3 4.37 3182.6 - 603215 - - - 3.2619 - 3.793 0.68 - 333.6 1 1 0 0.0092 28 0 0 0 1.09E+07 1.06E+07 - - - 9.1859 0.9984 221125_WJC_METTL3_EV_vs_WT_F08.19055.19055.4 0.000199 17/138 K.K[136.11]SPLALLAQTC[160.03]SQIGK[136.11]PDPPPSSK[136.11].L sp|Q9H7S9|ZN703_HUMAN 1 2543.3844 2.2 121091 19055 4 2543.397071 636.8534 Zinc finger protein 703 OS=Homo sapiens OX=9606 GN=ZNF703 PE=1 SV=1 9.2 3182.7 - 557563 - - - 4.9977 - 2.438 0.413 - 99.1 1 2 0 0.0127 24 0 0 0 8.17E+07 3.72E+07 - - - 3.1033 1 221125_WJC_METTL3_EV_vs_WT_F08.19063.19063.4 5.42E-13 25/156 R.ATDKDITGTLSNPEVFNYGVETHEAYK.Q "sp|P16083|NQO2_HUMAN,tr|Q5TD07|Q5TD07_HUMAN,tr|Q5TD05|Q5TD05_HUMAN" 3 2998.4196 1.33 121097 19063 4 2998.429391 750.6122 Ribosyldihydronicotinamide dehydrogenase [quinone] OS=Homo sapiens OX=9606 GN=NQO2 PE=1 SV=5 4.5 3183.8 - 603701 - - - 3.2614 - 4.993 0.642 - 436.7 1 2 1 0.0098 27 0 0 0 3.76E+07 2.82E+07 - - - 5.3144 0.9997 221125_WJC_METTL3_EV_vs_WT_F08.19066.19066.4 2.08E-06 16/126 K.KPEDNHTQC[160.03]QLVPVVEIGISER.Q sp|Q9NQS7|INCE_HUMAN 1 2547.2751 1.88 121100 19066 4 2547.287409 637.8261 Inner centromere protein OS=Homo sapiens OX=9606 GN=INCENP PE=1 SV=3 4.83 3184.2 - 503667 - - - 4.8177 - 3.169 0.521 - 143.5 1 2 0 0.0123 22 0 0 0 2.19E+07 1.17E+07 - - - 4.1348 0.9999 221125_WJC_METTL3_EV_vs_WT_F08.19079.19079.4 0.0307 25/156 R.ATDK[136.11]DITGTLSNPEVFNYGVETHEAYK[136.11].Q "sp|P16083|NQO2_HUMAN,tr|Q5TD07|Q5TD07_HUMAN,tr|Q5TD05|Q5TD05_HUMAN" 3 3014.448 1.33 121109 19079 4 3014.455175 754.6193 Ribosyldihydronicotinamide dehydrogenase [quinone] OS=Homo sapiens OX=9606 GN=NQO2 PE=1 SV=5 4.5 3185.9 - 564094 - - - 2.3762 - 5.161 0.602 - 310.1 1 2 1 0.0072 27 0 0 0 3.76E+07 2.82E+07 - - - 4.9773 0.9519 221125_WJC_METTL3_EV_vs_WT_F08.19081.19081.4 9.08E-05 10/114 K.HAASDVDLEIESLLNQQSTK[136.11].E "sp|Q86U44|MTA70_HUMAN,tr|F5H6D8|F5H6D8_HUMAN,tr|H0YFV6|H0YFV6_HUMAN,tr|B4DTN4|B4DTN4_HUMAN" 4 2205.1005 0 121111 19081 4 2206.114618 552.2824 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 4.31 3186.2 - 175569 - - - 459.9165 - 2.069 0.445 - 72 1 2 0 1.0142 20 0 0 0 9.22E+04 2.18E+07 - - - 3.0614 0.9999 221125_WJC_METTL3_EV_vs_WT_F08.19086.19086.4 3.54E-07 13/168 K.VNDNK[136.11]EPEQIAFQDEDEAQLNK[136.11]ENWTVVK[136.11].T sp|Q13112|CAF1B_HUMAN 1 3453.6751 0.44 121114 19086 4 3453.672758 864.426 Chromatin assembly factor 1 subunit B OS=Homo sapiens OX=9606 GN=CHAF1B PE=1 SV=1 4.12 3186.9 - 291958 - - - -0.666 - 3.205 0.528 - 66.1 1 2 2 -0.0023 29 0 0 0 4.35E+06 9.78E+06 - - - 4.18 0.9995 221125_WJC_METTL3_EV_vs_WT_F08.19089.19089.4 0.00443 14/192 R.SDSPVPTAPTSGGPK[136.11]PSTASAVPELATDPELEK[136.11].K "sp|Q86U44|MTA70_HUMAN,tr|B4E349|B4E349_HUMAN,tr|F5H6D8|F5H6D8_HUMAN,tr|B4DTN4|B4DTN4_HUMAN" 4 3248.6271 0 121115 19089 4 3248.633706 813.1641 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 4.18 3187.3 - 335364 - - - 2.0341 - 2.142 0.36 - 77.4 1 2 0 0.0066 33 0 0 0 5.79E+04 2.62E+07 - - - 2.5862 0.999 221125_WJC_METTL3_EV_vs_WT_F08.19098.19098.3 9.59E-11 15/80 V.K[136.11]GNPQGFNQGLDC[160.03]DVIVAEVR[166.11].S sp|Q86U44|MTA70_HUMAN 1 2333.1553 0.001 121122 19098 3 2333.155402 778.7257 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 4.56 3188.5 - 256633 - - - 0.0441 - 3.16 0.632 - 254.4 1 1 0 0.0001 21 0 0 0 0.00E+00 5.72E+06 - - - 8.3446 0.9954 221125_WJC_METTL3_EV_vs_WT_F08.19121.19121.4 6.34E-08 17/120 N.VRPVPLELHIQGFNISHTQTR.L sp|O75643|U520_HUMAN 1 2441.3292 1.97 121134 19121 4 2441.334197 611.3396 U5 small nuclear ribonucleoprotein 200 kDa helicase OS=Homo sapiens OX=9606 GN=SNRNP200 PE=1 SV=2 9.58 3191.5 - 249618 - - - 2.0628 - 3.035 0.538 - 186.7 1 1 0 0.005 21 0 0 0 5.01E+06 2.54E+06 - - - 4.2744 0.9993 221125_WJC_METTL3_EV_vs_WT_F08.19157.19157.3 4.22E-08 21/128 R.SDSPVPTAPTSGGPK[136.11]PSTASAVPELATDPELEK[136.11].K "sp|Q86U44|MTA70_HUMAN,tr|B4E349|B4E349_HUMAN,tr|F5H6D8|F5H6D8_HUMAN,tr|B4DTN4|B4DTN4_HUMAN" 4 3248.6271 0.01 121150 19157 3 3249.623587 1083.883 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 4.18 3196.4 - 1.35E+06 - - - 306.7416 - 3.288 0.61 - 166.1 1 2 0 0.9965 33 0 0 0 7.19E+05 1.06E+08 - - - 7.8033 1 221125_WJC_METTL3_EV_vs_WT_F08.19180.19180.4 9.39E-08 30/132 K.GRAEGEWEDQEALDYFSDKESGK.Q "sp|Q9NYF8|BCLF1_HUMAN,tr|E9PKI6|E9PKI6_HUMAN,tr|A0A1W2PQ43|A0A1W2PQ43_HUMAN,tr|E9PK91|E9PK91_HUMAN,tr|E9PK09|E9PK09_HUMAN,tr|E9PQN2|E9PQN2_HUMAN" 6 2645.1518 2.17 121160 19180 4 2645.152196 662.2952 Bcl-2-associated transcription factor 1 OS=Homo sapiens OX=9606 GN=BCLAF1 PE=1 SV=2 4.12 3199.4 - 2.12E+06 - - - 0.1614 - 4.812 0.616 - 610.3 1 2 2 0.0004 23 0 0 0 1.94E+08 8.97E+07 - - - 5.0966 1 221125_WJC_METTL3_EV_vs_WT_F08.19181.19181.4 4.08E-11 26/132 K.GR[166.11]AEGEWEDQEALDYFSDK[136.11]ESGK[136.11].Q "sp|Q9NYF8|BCLF1_HUMAN,tr|E9PKI6|E9PKI6_HUMAN,tr|A0A1W2PQ43|A0A1W2PQ43_HUMAN,tr|E9PK91|E9PK91_HUMAN,tr|E9PK09|E9PK09_HUMAN,tr|E9PQN2|E9PQN2_HUMAN" 6 2671.1884 2.17 121161 19181 4 2671.182569 668.8044 Bcl-2-associated transcription factor 1 OS=Homo sapiens OX=9606 GN=BCLAF1 PE=1 SV=2 4.12 3199.6 - 954051 - - - -2.1975 - 4.626 0.687 - 379.6 1 2 2 -0.0059 23 0 0 0 1.94E+08 8.97E+07 - - - 5.7003 0.9989 221125_WJC_METTL3_EV_vs_WT_F08.19182.19182.4 5.65E-05 11/138 R.QQGNEPSQILSLTGDRVPLHC[160.03]VDR.H sp|Q8NFH3|NUP43_HUMAN 1 2718.3508 2.36 121162 19182 4 2718.354149 680.595 Nucleoporin Nup43 OS=Homo sapiens OX=9606 GN=NUP43 PE=1 SV=1 5.38 3199.7 - 941235 - - - 1.2463 - 2.268 0.361 - 47 1 2 1 0.0034 24 0 0 0 1.36E+07 5.77E+06 - - - 2.63 1 221125_WJC_METTL3_EV_vs_WT_F08.19183.19183.3 7.65E-13 22/136 A.ASSLNSYGAQGSSLASYGNQPSSYGAQAASSYGVR.A sp|Q96PK6|RBM14_HUMAN 1 3442.5662 2.9 121163 19183 3 3442.562406 1148.5293 RNA-binding protein 14 OS=Homo sapiens OX=9606 GN=RBM14 PE=1 SV=2 8.47 3199.8 - 422372 - - - -1.0931 - 4.238 0.713 - 271 1 1 0 -0.0038 35 0 0 0 1.57E+07 5.41E+06 - - - 9.8105 1 221125_WJC_METTL3_EV_vs_WT_F08.19188.19188.3 2.95E-08 19/64 R.IINEPTAAAIAYGLDK[136.11]K[136.11].G "sp|P54652|HSP72_HUMAN,sp|P11142|HSP7C_HUMAN,tr|E9PKE3|E9PKE3_HUMAN,tr|E9PN89|E9PN89_HUMAN,tr|E9PI65|E9PI65_HUMAN" 5 1803.0113 0.53 121165 19188 3 1803.014564 602.011 Heat shock-related 70 kDa protein 2 OS=Homo sapiens OX=9606 GN=HSPA2 PE=1 SV=1 6.07 3200.4 - 873166 - - - 1.8103 - 3.403 0.583 - 433.3 1 2 0 0.0033 17 0 0 0 2.69E+07 5.08E+07 - - - 8.1328 1 221125_WJC_METTL3_EV_vs_WT_F08.19190.19190.4 3.14E-12 22/186 K.TYVVTGNMGSNDKVGDFVATDLDTGRPSTTVR.Y sp|Q02413|DSG1_HUMAN 1 3372.6256 999 121167 19190 4 3372.635183 844.1637 Desmoglein-1 OS=Homo sapiens OX=9606 GN=DSG1 PE=1 SV=2 4.58 3200.7 - 1.09E+06 - - - 2.842 - 4.333 0.647 - 189.7 1 2 1 0.0096 32 0 0 0 5.42E+07 0.00E+00 - - - 5.2975 0.9986 221125_WJC_METTL3_EV_vs_WT_F08.19192.19192.2 0.8 16-Aug R.LLLPGELAK[136.11].H "sp|Q8N257|H2B3B_HUMAN,sp|A0A2R8Y619|H2BE1_HUMAN,sp|P33778|H2B1B_HUMAN,sp|Q96A08|H2B1A_HUMAN,sp|Q5QNW6|H2B2F_HUMAN,sp|P58876|H2B1D_HUMAN,sp|Q99880|H2B1L_HUMAN,sp|P62807|H2B1C_HUMAN,sp|Q99877|H2B1N_HUMAN,sp|P57053|H2BFS_HUMAN,sp|P23527|H2B1O_HUMAN,sp|O60814|H2B1K_HUMAN,sp|Q93079|H2B1H_HUMAN,sp|Q99879|H2B1M_HUMAN,sp|Q16778|H2B2E_HUMAN,sp|P06899|H2B1J_HUMAN,tr|U3KQK0|U3KQK0_HUMAN" 17 960.6099 1.65 121169 19192 2 960.60914 481.3122 Histone H2B type 3-B OS=Homo sapiens OX=9606 GN=H2BU1 PE=1 SV=3 6 3200.9 - 214792 - - - -0.8099 - 1.503 0.267 - 160.8 1 2 0 -0.0008 9 0 0 0 1.64E+07 9.95E+06 - - - 2.1916 1 221125_WJC_METTL3_EV_vs_WT_F08.19196.19196.3 9.99E-15 30/88 K.GRAEGEWEDQEALDYFSDKESGK.Q "sp|Q9NYF8|BCLF1_HUMAN,tr|E9PKI6|E9PKI6_HUMAN,tr|A0A1W2PQ43|A0A1W2PQ43_HUMAN,tr|E9PK91|E9PK91_HUMAN,tr|E9PK09|E9PK09_HUMAN,tr|E9PQN2|E9PQN2_HUMAN" 6 2645.1518 2.6 121170 19196 3 2645.151259 882.7245 Bcl-2-associated transcription factor 1 OS=Homo sapiens OX=9606 GN=BCLAF1 PE=1 SV=2 4.12 3201.5 - 1.04E+06 - - - -0.1928 - 5.993 0.749 - 1510.5 1 2 2 -0.0005 23 0 0 0 3.90E+07 1.50E+07 - - - 11.0911 1 221125_WJC_METTL3_EV_vs_WT_F08.19198.19198.4 7.24E-11 31/198 A.SLFQQQAAAAAAATNSANQQTTPQAQQGQQQVLR.G "sp|Q14671|PUM1_HUMAN,tr|Q5T1Z8|Q5T1Z8_HUMAN,tr|H0YDK8|H0YDK8_HUMAN,tr|H0YEH2|H0YEH2_HUMAN,tr|Q5T1Z4|Q5T1Z4_HUMAN,tr|H0YED4|H0YED4_HUMAN,tr|E9PR38|E9PR38_HUMAN" 7 3553.7622 2.16 121172 19198 4 3553.76331 889.4478 Pumilio homolog 1 OS=Homo sapiens OX=9606 GN=PUM1 PE=1 SV=3 9.47 3201.8 - 1.12E+06 - - - 0.3168 - 5.345 0.668 - 525.1 1 1 0 0.0011 34 0 0 0 3.26E+07 1.51E+07 - - - 5.5398 1 221125_WJC_METTL3_EV_vs_WT_F08.19207.19207.3 2.71E-15 22/132 A.SLFQQQAAAAAAATNSANQQTTPQAQQGQQQVLR.G "sp|Q14671|PUM1_HUMAN,tr|Q5T1Z8|Q5T1Z8_HUMAN,tr|H0YDK8|H0YDK8_HUMAN,tr|H0YEH2|H0YEH2_HUMAN,tr|Q5T1Z4|Q5T1Z4_HUMAN,tr|H0YED4|H0YED4_HUMAN,tr|E9PR38|E9PR38_HUMAN" 7 3553.7622 3.29 121177 19207 3 3553.761937 1185.5947 Pumilio homolog 1 OS=Homo sapiens OX=9606 GN=PUM1 PE=1 SV=3 9.47 3203.1 - 802694 - - - -0.0695 - 4.268 0.684 - 299.8 1 1 0 -0.0002 34 0 0 0 2.04E+07 6.22E+06 - - - 9.5044 0.9979 221125_WJC_METTL3_EV_vs_WT_F08.19208.19208.2 0.0324 16-Aug R.LLLPGELAK.H "sp|Q8N257|H2B3B_HUMAN,sp|A0A2R8Y619|H2BE1_HUMAN,sp|P33778|H2B1B_HUMAN,sp|Q96A08|H2B1A_HUMAN,sp|Q5QNW6|H2B2F_HUMAN,sp|P58876|H2B1D_HUMAN,sp|Q99880|H2B1L_HUMAN,sp|P62807|H2B1C_HUMAN,sp|Q99877|H2B1N_HUMAN,sp|P57053|H2BFS_HUMAN,sp|P23527|H2B1O_HUMAN,sp|O60814|H2B1K_HUMAN,sp|Q93079|H2B1H_HUMAN,sp|Q99879|H2B1M_HUMAN,sp|Q16778|H2B2E_HUMAN,sp|P06899|H2B1J_HUMAN,tr|U3KQK0|U3KQK0_HUMAN" 17 952.5957 1.65 121178 19208 2 952.595046 477.3051 Histone H2B type 3-B OS=Homo sapiens OX=9606 GN=H2BU1 PE=1 SV=3 6 3203.2 - 476416 - - - -0.7054 - 1.4 0.241 - 187.1 1 2 0 -0.0007 9 0 0 0 1.64E+07 9.95E+06 - - - 1.7942 0.9989 221125_WJC_METTL3_EV_vs_WT_F08.19209.19209.3 4.34E-07 12/136 A.ASSLNSYGAQGSSLASYGNQPSSYGAQAASSYGVR[166.11].A sp|Q96PK6|RBM14_HUMAN 1 3452.5744 2.9 121179 19209 3 3452.575285 1151.8654 RNA-binding protein 14 OS=Homo sapiens OX=9606 GN=RBM14 PE=1 SV=2 8.47 3203.4 - 507963 - - - 0.245 - 2.778 0.663 - 73 1 1 0 0.0008 35 0 0 0 1.57E+07 5.41E+06 - - - 8.2822 1 221125_WJC_METTL3_EV_vs_WT_F08.19214.19214.4 4.56E-09 28/198 A.SLFQQQAAAAAAATNSANQQTTPQAQQGQQQVLR[166.11].G "sp|Q14671|PUM1_HUMAN,tr|Q5T1Z8|Q5T1Z8_HUMAN,tr|H0YDK8|H0YDK8_HUMAN,tr|H0YEH2|H0YEH2_HUMAN,tr|Q5T1Z4|Q5T1Z4_HUMAN,tr|H0YED4|H0YED4_HUMAN,tr|E9PR38|E9PR38_HUMAN" 7 3563.7705 2.16 121182 19214 4 3563.767057 891.9499 Pumilio homolog 1 OS=Homo sapiens OX=9606 GN=PUM1 PE=1 SV=3 9.47 3204 - 872118 - - - -0.9532 - 4.751 0.622 - 431.1 1 1 0 -0.0034 34 0 0 0 3.26E+07 1.51E+07 - - - 5.1037 1 221125_WJC_METTL3_EV_vs_WT_F08.19216.19216.3 1.35E-11 22/64 R.IINEPTAAAIAYGLDKK.G "sp|P54652|HSP72_HUMAN,sp|P11142|HSP7C_HUMAN,tr|E9PKE3|E9PKE3_HUMAN,tr|E9PN89|E9PN89_HUMAN,tr|E9PI65|E9PI65_HUMAN" 5 1786.9829 0.53 121184 19216 3 1786.983736 596.6682 Heat shock-related 70 kDa protein 2 OS=Homo sapiens OX=9606 GN=HSPA2 PE=1 SV=1 6.07 3204.3 - 1.51E+06 - - - 0.4678 - 3.846 0.501 - 544.4 1 2 0 0.0008 17 0 0 0 2.69E+07 5.08E+07 - - - 7.5284 0.9999 221125_WJC_METTL3_EV_vs_WT_F08.19222.19222.4 1.05E-07 20/102 R.EREQIKSLNNQFASFIDK.V sp|P04264|K2C1_HUMAN 1 2166.1069 26.65 121188 19222 4 2166.105897 542.534 "Keratin, type II cytoskeletal 1 OS=Homo sapiens OX=9606 GN=KRT1 PE=1 SV=6" 6.28 3205 - 627613 - - - -0.4778 - 3.888 0.493 - 376.3 1 2 2 -0.001 18 0 0 0 1.36E+07 5.11E+05 - - - 3.9819 0.9999 221125_WJC_METTL3_EV_vs_WT_F08.19229.19229.4 0.000696 12/138 K.EQLYQQAMEEAAWHHMPHPSDSER.L "sp|O75175|CNOT3_HUMAN,tr|A0A2R8Y691|A0A2R8Y691_HUMAN,tr|B7Z6J7|B7Z6J7_HUMAN,tr|A0A2H2FJL5|A0A2H2FJL5_HUMAN,tr|H7C3F5|H7C3F5_HUMAN,tr|H0Y5X7|H0Y5X7_HUMAN" 6 2906.2501 3.15 121193 19229 4 2906.249783 727.5698 CCR4-NOT transcription complex subunit 3 OS=Homo sapiens OX=9606 GN=CNOT3 PE=1 SV=1 4.89 3205.9 - 175170 - - - -0.0953 - 2.004 0.418 - 64.3 1 2 0 -0.0003 24 0 0 0 7.48E+06 2.38E+06 - - - 3.0873 0.9999 221125_WJC_METTL3_EV_vs_WT_F08.19251.19251.4 6.83E-09 20/144 K.C[160.03]TTDENKVPYFNAPVYLENKEQIGK.V sp|Q9NY12|GAR1_HUMAN 1 2956.4277 0.79 121207 19251 4 2956.431646 740.1142 H\ACA ribonucleoprotein complex subunit 1 OS=Homo sapiens OX=9606 GN=GAR1 PE=1 SV=1 4.87 3208.7 - 559265 - - - 1.3435 - 3.862 0.578 - 190.3 1 2 2 0.004 25 0 0 0 7.57E+06 9.52E+06 - - - 4.6857 0.9998 221125_WJC_METTL3_EV_vs_WT_F08.19256.19256.3 0.000831 Aug-52 K.K[136.11]GPGEVAGTVTGQK[136.11].R "sp|Q86U44|MTA70_HUMAN,tr|F5H6D8|F5H6D8_HUMAN,tr|H0YFV6|H0YFV6_HUMAN,tr|B4DTN4|B4DTN4_HUMAN" 4 1343.738 0.001 121210 19256 3 1343.735902 448.9199 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 8.59 3209.4 - 154990 - - - -1.5457 - 1.893 0.427 - 75.7 1 2 0 -0.0021 14 0 0 0 0.00E+00 3.38E+06 - - - 4.996 1 221125_WJC_METTL3_EV_vs_WT_F08.19259.19259.4 3.81E-14 25/156 K.IGEEQSAEDAEDGPPELLFIHGGHTAK.L "sp|Q16576|RBBP7_HUMAN,tr|Q5JNZ6|Q5JNZ6_HUMAN,tr|E9PC52|E9PC52_HUMAN" 3 2846.3359 1.37 121212 19259 4 2846.341057 712.5912 Histone-binding protein RBBP7 OS=Homo sapiens OX=9606 GN=RBBP7 PE=1 SV=1 4.24 3209.8 - 703157 - - - 1.8181 - 4.544 0.693 - 476.5 1 2 0 0.0052 27 0 0 0 4.76E+07 3.47E+07 - - - 5.7301 1 221125_WJC_METTL3_EV_vs_WT_F08.19267.19267.3 4.14E-06 13/56 R.STSHK[136.11]PDEIYGMIER[166.11].L sp|Q86U44|MTA70_HUMAN 1 1779.8581 0.05 121217 19267 3 1779.85908 594.2933 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 5.42 3210.8 - 268091 - - - 0.5765 - 2.521 0.496 - 225.7 1 2 0 0.001 15 0 0 0 9.64E+05 2.01E+07 - - - 6.4824 1 221125_WJC_METTL3_EV_vs_WT_F08.19272.19272.4 3.87E-08 29/186 K.LAEEEDLFDSAHPEEGDLDLASESTAHAQSSK[136.11].A "sp|Q14151|SAFB2_HUMAN,sp|Q15424|SAFB1_HUMAN" 2 3435.5317 1.52 121220 19272 4 3435.535555 859.8902 Scaffold attachment factor B2 OS=Homo sapiens OX=9606 GN=SAFB2 PE=1 SV=1 3.96 3211.4 - 657176 - - - 1.1084 - 4.835 0.692 - 575 1 2 0 0.0038 32 0 0 0 1.19E+08 7.83E+07 - - - 5.7239 0.9998 221125_WJC_METTL3_EV_vs_WT_F08.19274.19274.4 4.62E-06 14/132 K.QAFFHLYHPLGSQHPFSAGGVGR.S "sp|Q9Y467|SALL2_HUMAN,tr|F5H433|F5H433_HUMAN,tr|E7EW59|E7EW59_HUMAN,tr|H0YFS7|H0YFS7_HUMAN" 4 2509.2403 1.01 121222 19274 4 2509.246046 628.3174 Sal-like protein 2 OS=Homo sapiens OX=9606 GN=SALL2 PE=1 SV=4 8.77 3211.7 - 353967 - - - 2.2716 - 2.795 0.42 - 115.2 1 2 0 0.0057 23 0 0 0 4.73E+06 4.67E+06 - - - 3.2131 1 221125_WJC_METTL3_EV_vs_WT_F08.19281.19281.3 2.71E-15 17/112 K.KAALDEAQGVGLDSTGYYDQEIYGGSDSR.F "sp|O75533|SF3B1_HUMAN,tr|B4DGZ4|B4DGZ4_HUMAN,tr|A0A494C1M2|A0A494C1M2_HUMAN" 3 3064.3898 1.37 121226 19281 3 3064.385088 1022.4705 Splicing factor 3B subunit 1 OS=Homo sapiens OX=9606 GN=SF3B1 PE=1 SV=3 3.96 3212.6 - 377329 - - - -1.5272 - 3.669 0.765 - 215.6 1 2 0 -0.0047 29 0 0 0 7.57E+06 5.55E+06 - - - 10.0583 0.9998 221125_WJC_METTL3_EV_vs_WT_F08.19283.19283.4 1.17E-05 14/132 K.QAFFHLYHPLGSQHPFSAGGVGR[166.11].S "sp|Q9Y467|SALL2_HUMAN,tr|F5H433|F5H433_HUMAN,tr|E7EW59|E7EW59_HUMAN,tr|H0YFS7|H0YFS7_HUMAN" 4 2519.2486 1.07 121228 19283 4 2519.250543 630.8194 Sal-like protein 2 OS=Homo sapiens OX=9606 GN=SALL2 PE=1 SV=4 8.77 3212.8 - 319468 - - - 0.7649 - 2.562 0.391 - 105.8 1 2 0 0.0019 23 0 0 0 4.44E+06 4.17E+06 - - - 2.9335 1 221125_WJC_METTL3_EV_vs_WT_F08.19287.19287.3 6.17E-12 15/112 K.K[136.11]AALDEAQGVGLDSTGYYDQEIYGGSDSR[166.11].F "sp|O75533|SF3B1_HUMAN,tr|B4DGZ4|B4DGZ4_HUMAN,tr|A0A494C1M2|A0A494C1M2_HUMAN" 3 3082.4122 1.37 121230 19287 3 3082.425007 1028.478 Splicing factor 3B subunit 1 OS=Homo sapiens OX=9606 GN=SF3B1 PE=1 SV=3 3.96 3213.4 - 399015 - - - 4.1425 - 3.212 0.724 - 173.9 1 2 0 0.0128 29 0 0 0 7.57E+06 5.55E+06 - - - 9.2929 1 221125_WJC_METTL3_EV_vs_WT_F08.19288.19288.4 4.24E-12 31/186 K.LAEEEDLFDSAHPEEGDLDLASESTAHAQSSK.A "sp|Q14151|SAFB2_HUMAN,sp|Q15424|SAFB1_HUMAN" 2 3427.5175 1.52 121231 19288 4 3427.519574 857.8867 Scaffold attachment factor B2 OS=Homo sapiens OX=9606 GN=SAFB2 PE=1 SV=1 3.96 3213.5 - 3.71E+06 - - - 0.5914 - 4.886 0.689 - 508.6 1 2 0 0.002 32 0 0 0 1.19E+08 7.83E+07 - - - 5.7015 1 221125_WJC_METTL3_EV_vs_WT_F08.19296.19296.3 2.17E-11 21/124 K.LAEEEDLFDSAHPEEGDLDLASESTAHAQSSK.A "sp|Q14151|SAFB2_HUMAN,sp|Q15424|SAFB1_HUMAN" 2 3427.5175 3.22 121237 19296 3 3427.517474 1143.5131 Scaffold attachment factor B2 OS=Homo sapiens OX=9606 GN=SAFB2 PE=1 SV=1 3.96 3214.5 - 278269 - - - -0.0213 - 4.522 0.767 - 333.9 1 2 0 -0.0001 32 0 0 0 6.00E+06 1.86E+06 - - - 10.5628 1 221125_WJC_METTL3_EV_vs_WT_F08.19301.19301.3 3.36E-09 14/124 R.LDTEAPYC[160.03]GPSSYNQGQESGAGC[160.03]GPGDVFPER.R sp|Q5T749|KPRP_HUMAN 1 3401.4201 999 121240 19301 3 3401.413085 1134.814 Keratinocyte proline-rich protein OS=Homo sapiens OX=9606 GN=KPRP PE=1 SV=1 3.83 3215.2 - 197985 - - - -2.0621 - 3.174 0.731 - 91.8 1 2 0 -0.007 32 0 0 0 5.19E+06 0.00E+00 - - - 9.3452 1 221125_WJC_METTL3_EV_vs_WT_F08.19309.19309.3 3.30E-13 19/88 K.EIETYHNLLEGGQEDFESSGAGK.L "sp|P35527|K1C9_HUMAN,tr|K7EQQ3|K7EQQ3_HUMAN" 2 2509.1245 1072.86 121245 19309 3 2509.1237 837.3821 "Keratin, type I cytoskeletal 9 OS=Homo sapiens OX=9606 GN=KRT9 PE=1 SV=3" 4.14 3216.2 - 548262 - - - -0.3156 - 4.139 0.669 - 491 1 2 0 -0.0008 23 0 0 0 4.14E+08 3.86E+05 - - - 9.3308 1 221125_WJC_METTL3_EV_vs_WT_F08.19316.19316.4 2.44E-06 23/102 K.RPENSLLEETLHFDHAVR.M "sp|O00566|MPP10_HUMAN,tr|U3KQ48|U3KQ48_HUMAN" 2 2162.0869 999 121250 19316 4 2162.090851 541.529 U3 small nucleolar ribonucleoprotein protein MPP10 OS=Homo sapiens OX=9606 GN=MPHOSPH10 PE=1 SV=2 5.36 3217.1 - 632538 - - - 1.8436 - 2.833 0.518 - 234.4 1 2 0 0.004 18 0 0 0 3.03E+07 0.00E+00 - - - 4.0903 1 221125_WJC_METTL3_EV_vs_WT_F08.19319.19319.4 2.88E-15 27/156 K.IGEEQSPEDAEDGPPELLFIHGGHTAK.L "sp|Q09028|RBBP4_HUMAN,tr|H0YCT5|H0YCT5_HUMAN,tr|H0YDK2|H0YDK2_HUMAN,tr|H0YEU5|H0YEU5_HUMAN,tr|H0YF10|H0YF10_HUMAN" 5 2872.3515 1.81 121251 19319 4 2872.35456 719.0952 Histone-binding protein RBBP4 OS=Homo sapiens OX=9606 GN=RBBP4 PE=1 SV=3 4.24 3217.5 - 768626 - - - 1.0542 - 4.073 0.699 - 160.7 1 2 0 0.003 27 0 0 0 6.17E+07 3.40E+07 - - - 5.7487 0.9999 221125_WJC_METTL3_EV_vs_WT_F08.19321.19321.4 3.41E-06 8/138 K.HTSVIQSTGLVSNVK[136.11]PLSLVNQAK[136.11].K "sp|Q9UIF8|BAZ2B_HUMAN,tr|A0A0A0MR97|A0A0A0MR97_HUMAN" 2 2535.4355 1.23 121253 19321 4 2535.440227 634.8662 Bromodomain adjacent to zinc finger domain protein 2B OS=Homo sapiens OX=9606 GN=BAZ2B PE=1 SV=3 10 3217.7 - 156507 - - - 1.8498 - 1.702 0.483 - 29.8 1 2 0 0.0047 24 0 0 0 4.65E+06 3.79E+06 - - - 3.5994 1 221125_WJC_METTL3_EV_vs_WT_F08.19325.19325.4 1.25E-11 24/156 K.IGEEQSPEDAEDGPPELLFIHGGHTAK[136.11].L "sp|Q09028|RBBP4_HUMAN,tr|H0YCT5|H0YCT5_HUMAN,tr|H0YDK2|H0YDK2_HUMAN,tr|H0YEU5|H0YEU5_HUMAN,tr|H0YF10|H0YF10_HUMAN" 5 2880.3657 2.01 121255 19325 4 2880.363074 721.0987 Histone-binding protein RBBP4 OS=Homo sapiens OX=9606 GN=RBBP4 PE=1 SV=3 4.24 3218.3 - 648797 - - - -0.9228 - 3.588 0.668 - 120.7 1 2 0 -0.0027 27 0 0 0 9.82E+07 4.87E+07 - - - 5.4393 1 221125_WJC_METTL3_EV_vs_WT_F08.19326.19326.2 3.51E-07 22-Aug K.SFFDNISC[160.03]DDNR[166.11].E "sp|Q8ND56|LS14A_HUMAN,tr|A0A096LP11|A0A096LP11_HUMAN,tr|A0A140TA76|A0A140TA76_HUMAN,tr|A0A0G2JQ95|A0A0G2JQ95_HUMAN" 4 1498.6022 0.75 121256 19326 2 1498.602339 750.3084 Protein LSM14 homolog A OS=Homo sapiens OX=9606 GN=LSM14A PE=1 SV=3 3.93 3218.4 - 134764 - - - 0.0747 - 1.973 0.689 - 195.3 1 2 0 0.0001 12 0 0 0 4.43E+06 5.91E+06 - - - 5.9179 0.9945 221125_WJC_METTL3_EV_vs_WT_F08.19332.19332.3 2.19E-05 15/104 M.SSSLNQQGAHSALSSASTSSHNLQSIF.- tr|D6RBS2|D6RBS2_HUMAN 1 2745.2954 - 121260 19332 3 2745.294468 916.1057 Matrin-3 (Fragment) OS=Homo sapiens OX=9606 GN=MATR3 PE=1 SV=1 6.66 3219.1 - 601632 - - - -0.3446 - 2.538 0.464 - 150.6 1 1 0 -0.0009 27 0 0 0 - - - - - 5.8556 1 221125_WJC_METTL3_EV_vs_WT_F08.19336.19336.4 9.34E-09 17/150 K.EIENGVYLINGQVKDEDC[160.03]DLLEGQKK.S sp|Q5SWX8|ODR4_HUMAN 1 3005.4652 1.55 121262 19336 4 3005.466773 752.3736 Protein odr-4 homolog OS=Homo sapiens OX=9606 GN=ODR4 PE=1 SV=1 4.2 3219.6 - 487490 - - - 0.5294 - 3.302 0.632 - 130.1 1 2 1 0.0016 26 0 0 0 3.95E+07 2.55E+07 - - - 5.1033 0.9999 221125_WJC_METTL3_EV_vs_WT_F08.19339.19339.4 9.51E-07 14/120 R.SQYEQLAEQNRKDAEAWFNEK.S "sp|P13645|K1C10_HUMAN,tr|A0A1B0GVI3|A0A1B0GVI3_HUMAN" 2 2583.199 201.46 121265 19339 4 2583.197234 646.807 "Keratin, type I cytoskeletal 10 OS=Homo sapiens OX=9606 GN=KRT10 PE=1 SV=6" 4.58 3220 - 700025 - - - -0.6813 - 2.747 0.497 - 115.6 1 2 1 -0.0018 21 0 0 0 8.07E+07 4.01E+05 - - - 3.8855 0.8676 221125_WJC_METTL3_EV_vs_WT_F08.19352.19352.3 0.00228 10/100 S.SSLNQQGAHSALSSASTSSHNLQSIF.- tr|D6RBS2|D6RBS2_HUMAN 1 2658.2634 - 121272 19352 3 2658.268781 887.0951 Matrin-3 (Fragment) OS=Homo sapiens OX=9606 GN=MATR3 PE=1 SV=1 6.66 3221.7 - 365256 - - - 2.0295 - 2.021 0.303 - 65 1 1 0 0.0054 26 0 0 0 - - - - - 3.5354 0.9999 221125_WJC_METTL3_EV_vs_WT_F08.19363.19363.3 3.95E-10 16/80 R.SQYEQLAEQNRKDAEAWFNEK.S "sp|P13645|K1C10_HUMAN,tr|A0A1B0GVI3|A0A1B0GVI3_HUMAN" 2 2583.199 999 121277 19363 3 2583.201709 862.0736 "Keratin, type I cytoskeletal 10 OS=Homo sapiens OX=9606 GN=KRT10 PE=1 SV=6" 4.58 3223.1 - 518707 - - - 1.051 - 3.278 0.604 - 250.2 1 2 1 0.0027 21 0 0 0 1.72E+07 0.00E+00 - - - 8.1196 0.9999 221125_WJC_METTL3_EV_vs_WT_F08.19369.19369.4 1.76E-07 24/150 K.EIENGVYLINGQVK[136.11]DEDC[160.03]DLLEGQK[136.11]K[136.11].S sp|Q5SWX8|ODR4_HUMAN 1 3029.5078 1.55 121280 19369 4 3029.511561 758.3842 Protein odr-4 homolog OS=Homo sapiens OX=9606 GN=ODR4 PE=1 SV=1 4.2 3223.9 - 949004 - - - 1.2474 - 3.953 0.615 - 259 1 2 1 0.0038 26 0 0 0 3.95E+07 2.55E+07 - - - 5.0115 1 221125_WJC_METTL3_EV_vs_WT_F08.19376.19376.4 1.93E-06 14/150 K.GYEEVHVPALKPKPFGSEEQLLPVEK.L "sp|O75643|U520_HUMAN,tr|A0A494C1A5|A0A494C1A5_HUMAN" 2 2919.5382 2.77 121284 19376 4 2919.543362 730.8918 U5 small nuclear ribonucleoprotein 200 kDa helicase OS=Homo sapiens OX=9606 GN=SNRNP200 PE=1 SV=2 5.02 3224.8 - 369275 - - - 1.7643 - 2.799 0.538 - 62.5 1 2 0 0.0052 26 0 0 0 2.47E+07 8.89E+06 - - - 4.232 1 221125_WJC_METTL3_EV_vs_WT_F08.19387.19387.4 1.72E-13 23/174 K.GKDEAMAIGGHWSPSLDGPDPEKDPSVLIK.T "sp|Q8IX12|CCAR1_HUMAN,tr|F5H2E6|F5H2E6_HUMAN,tr|F5H1H2|F5H1H2_HUMAN,tr|A0A0C4DGG8|A0A0C4DGG8_HUMAN,tr|F5H3E1|F5H3E1_HUMAN" 5 3145.539 3.34 121289 19387 4 3145.548789 787.392 Cell division cycle and apoptosis regulator protein 1 OS=Homo sapiens OX=9606 GN=CCAR1 PE=1 SV=2 4.52 3226.2 - 428341 - - - 3.1073 - 4.393 0.676 - 250.6 1 2 2 0.0098 30 0 0 0 1.26E+07 3.76E+06 - - - 5.5601 1 221125_WJC_METTL3_EV_vs_WT_F08.19389.19389.3 6.25E-08 13/104 K.IGEEQSPEDAEDGPPELLFIHGGHTAK.L "sp|Q09028|RBBP4_HUMAN,tr|H0YCT5|H0YCT5_HUMAN,tr|H0YDK2|H0YDK2_HUMAN,tr|H0YEU5|H0YEU5_HUMAN,tr|H0YF10|H0YF10_HUMAN" 5 2872.3515 3.35 121291 19389 3 2872.354469 958.4578 Histone-binding protein RBBP4 OS=Homo sapiens OX=9606 GN=RBBP4 PE=1 SV=3 4.24 3226.4 - 193239 - - - 1.0225 - 3.013 0.59 - 155.2 1 2 0 0.0029 27 0 0 0 5.02E+06 1.50E+06 - - - 7.6546 0.9999 221125_WJC_METTL3_EV_vs_WT_F08.19390.19390.4 6.94E-06 13/96 R.K[136.11]FDEVLVNHFC[160.03]EEFGK[136.11]K[136.11].Y "sp|P34932|HSP74_HUMAN,tr|A0A087WTS8|A0A087WTS8_HUMAN,tr|A0A087WYC1|A0A087WYC1_HUMAN" 3 2149.0729 0.08 121292 19390 4 2149.078765 538.2755 Heat shock 70 kDa protein 4 OS=Homo sapiens OX=9606 GN=HSPA4 PE=1 SV=4 5.53 3226.6 - 155337 - - - 2.7468 - 2.824 0.491 - 181.7 1 2 0 0.0059 17 0 0 0 9.68E+05 1.17E+07 - - - 3.8585 0.9998 221125_WJC_METTL3_EV_vs_WT_F08.19394.19394.3 4.75E-07 18/52 K.NKLNDLEDALQQAK.E sp|P04264|K2C1_HUMAN 1 1598.8264 400.65 121294 19394 3 1598.82956 533.9494 "Keratin, type II cytoskeletal 1 OS=Homo sapiens OX=9606 GN=KRT1 PE=1 SV=6" 4.56 3227.1 - 629884 - - - 1.9764 - 2.782 0.509 - 205.4 1 2 1 0.0032 14 0 0 0 1.72E+08 4.29E+05 - - - 6.9331 0.9992 221125_WJC_METTL3_EV_vs_WT_F08.19395.19395.4 1.28E-05 11/132 R.DNWSSSDGK[136.11]DDPIEVSK[136.11]DSIFVK[136.11].L sp|Q8WUM0|NU133_HUMAN 1 2591.2453 7.79 121295 19395 4 2591.255172 648.8186 Nuclear pore complex protein Nup133 OS=Homo sapiens OX=9606 GN=NUP133 PE=1 SV=2 4.17 3227.2 - 296918 - - - 3.7935 - 2.376 0.506 - 63.8 1 2 2 0.0098 23 0 0 0 4.45E+07 5.71E+06 - - - 3.9079 0.977 221125_WJC_METTL3_EV_vs_WT_F08.19396.19396.3 0.00499 Oct-64 R.GAPPSSNIEDFHGLLPK.G "sp|P43243|MATR3_HUMAN,tr|A8MXP9|A8MXP9_HUMAN,tr|D6R991|D6R991_HUMAN,tr|A0A0R4J2E8|A0A0R4J2E8_HUMAN,tr|H0Y8T4|H0Y8T4_HUMAN,tr|D6REM6|D6REM6_HUMAN" 6 1777.8999 1.35 121296 19396 3 1777.910546 593.6406 Matrin-3 OS=Homo sapiens OX=9606 GN=MATR3 PE=1 SV=2 5.32 3227.4 - 291333 - - - 5.9885 - 1.603 0.342 - 93.8 1 2 0 0.0106 17 0 0 0 6.16E+07 4.56E+07 - - - 3.5421 0.9092 221125_WJC_METTL3_EV_vs_WT_F08.19400.19400.4 0.106 10/120 R.SHFEQWGTLTDC[160.03]VVMR[166.11]DPNTK[136.11].R "sp|Q32P51|RA1L2_HUMAN,sp|P09651|ROA1_HUMAN,tr|F8W646|F8W646_HUMAN,tr|F8VZ49|F8VZ49_HUMAN,tr|A0A7I2V3R8|A0A7I2V3R8_HUMAN,tr|F8W6I7|F8W6I7_HUMAN,tr|A0A7I2V2L6|A0A7I2V2L6_HUMAN,tr|A0A7I2V3W0|A0A7I2V3W0_HUMAN" 8 2538.175 1.02 121300 19400 4 2538.18044 635.551 Heterogeneous nuclear ribonucleoprotein A1-like 2 OS=Homo sapiens OX=9606 GN=HNRNPA1L2 PE=2 SV=2 5.36 3227.9 - 218162 - - - 2.1244 - 2.061 0.181 - 63 1 2 1 0.0054 21 0 0 0 4.29E+06 4.21E+06 - - - 1.039 0.994 221125_WJC_METTL3_EV_vs_WT_F08.19401.19401.3 3.62E-05 Oct-92 K.SGNSDVYENEIPGGQYTNLHFQAH.S sp|P11498|PYC_HUMAN 1 2676.1841 - 121301 19401 3 2676.184875 893.0686 "Pyruvate carboxylase, mitochondrial OS=Homo sapiens OX=9606 GN=PC PE=1 SV=2" 4.62 3228 - 152270 - - - 0.2997 - 2.181 0.485 - 63.4 1 1 0 0.0008 24 0 0 0 - - - - - 5.7582 0.9968 221125_WJC_METTL3_EV_vs_WT_F08.19410.19410.4 0.0304 10/192 R.SDSPVPTAPTSGGPK[136.11]PSTASAVPELATDPELEK[136.11].K "sp|Q86U44|MTA70_HUMAN,tr|B4E349|B4E349_HUMAN,tr|F5H6D8|F5H6D8_HUMAN,tr|B4DTN4|B4DTN4_HUMAN" 4 3248.6271 0.01 121306 19410 4 3248.636069 813.1641 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 4.18 3229.3 - 244122 - - - 2.7615 - 1.945 0.293 - 31.9 1 2 0 0.009 33 0 0 0 7.88E+04 8.36E+06 - - - 1.9734 1 221125_WJC_METTL3_EV_vs_WT_F08.19411.19411.4 1.44E-09 23/234 R.LPAGYTLHETPPAGASPVLTPQESQSALEAAAANGGQRPR.E sp|P0C7T5|ATX1L_HUMAN 1 4010.0246 1.98 121307 19411 4 4010.031059 1003.5134 Ataxin-1-like OS=Homo sapiens OX=9606 GN=ATXN1L PE=1 SV=1 5.5 3229.4 - 234591 - - - 1.6092 - 3.13 0.586 - 118.6 1 2 0 0.0065 40 0 0 0 5.75E+07 2.90E+07 - - - 4.6541 1 221125_WJC_METTL3_EV_vs_WT_F08.19417.19417.4 1.90E-12 27/204 R.DPYC[160.03]LSYHC[160.03]ASHLAGAAAASASC[160.03]AHDPAAAAAALK.S sp|Q96F45|ZN503_HUMAN 1 3526.5816 1.37 121311 19417 4 3526.592037 882.6527 Zinc finger protein 503 OS=Homo sapiens OX=9606 GN=ZNF503 PE=1 SV=1 6.25 3230.2 - 541717 - - - 2.9473 - 4.707 0.696 - 217.1 1 2 0 0.0104 35 0 0 0 1.29E+07 9.43E+06 - - - 5.7403 0.9962 221125_WJC_METTL3_EV_vs_WT_F08.19418.19418.4 1.29E-05 14/138 K.TGTLQDLIQHGSPINNEC[160.03]HPSLER[166.11].K "sp|Q5VWN6|TASO2_HUMAN,tr|A0A2R8YH03|A0A2R8YH03_HUMAN" 2 2725.3117 0.6 121312 19418 4 2726.318862 682.3352 Protein TASOR 2 OS=Homo sapiens OX=9606 GN=TASOR2 PE=1 SV=1 5.26 3230.4 - 296386 - - - 369.5412 - 2.601 0.447 - 92.2 1 2 0 1.0071 24 0 0 0 1.29E+07 2.15E+07 - - - 3.1445 0.9965 221125_WJC_METTL3_EV_vs_WT_F08.19419.19419.3 2.53E-05 Nov-64 R.GAPPSSNIEDFHGLLPK[136.11].G "sp|P43243|MATR3_HUMAN,tr|A8MXP9|A8MXP9_HUMAN,tr|D6R991|D6R991_HUMAN,tr|A0A0R4J2E8|A0A0R4J2E8_HUMAN,tr|H0Y8T4|H0Y8T4_HUMAN,tr|D6REM6|D6REM6_HUMAN" 6 1785.9141 1.48 121313 19419 3 1785.92597 596.312 Matrin-3 OS=Homo sapiens OX=9606 GN=MATR3 PE=1 SV=2 5.32 3230.5 - 271007 - - - 6.647 - 2.021 0.467 - 123.9 1 2 0 0.0119 17 0 0 0 6.05E+07 4.09E+07 - - - 5.5208 0.9737 221125_WJC_METTL3_EV_vs_WT_F08.19422.19422.4 1.08 Aug-96 K.EIK[136.11]DTEK[136.11]EVDDLTAELK[136.11].S "sp|Q9NTJ3|SMC4_HUMAN,tr|E9PD53|E9PD53_HUMAN" 2 1999.0423 0.57 121316 19422 4 1999.047279 500.7679 Structural maintenance of chromosomes protein 4 OS=Homo sapiens OX=9606 GN=SMC4 PE=1 SV=2 4.2 3230.9 - 82294.5 - - - 2.4747 - 1.538 0.255 - 56.6 1 2 2 0.0049 17 0 0 0 1.34E+06 2.33E+06 - - - 1.5936 1 221125_WJC_METTL3_EV_vs_WT_F08.19425.19425.4 1.03E-07 33/132 K.DFDFESANAQFNKEEIDREFHNK.L "sp|Q8ND56|LS14A_HUMAN,tr|A0A140TA76|A0A140TA76_HUMAN,tr|K7EMZ9|K7EMZ9_HUMAN" 3 2829.2631 0.99 121317 19425 4 2829.270389 708.323 Protein LSM14 homolog A OS=Homo sapiens OX=9606 GN=LSM14A PE=1 SV=3 4.43 3231.3 - 6.22E+06 - - - 2.5936 - 5.38 0.607 - 440 1 2 2 0.0073 23 0 0 0 2.60E+09 2.61E+09 - - - 5.0525 0.9979 221125_WJC_METTL3_EV_vs_WT_F08.19427.19427.3 2.74E-08 18/88 K.DFDFESANAQFNK[136.11]EEIDR[166.11]EFHNK[136.11].L "sp|Q8ND56|LS14A_HUMAN,tr|A0A140TA76|A0A140TA76_HUMAN,tr|K7EMZ9|K7EMZ9_HUMAN" 3 2855.2997 0.97 121319 19427 3 2855.30753 952.7739 Protein LSM14 homolog A OS=Homo sapiens OX=9606 GN=LSM14A PE=1 SV=3 4.43 3231.6 - 492562 - - - 2.7349 - 2.952 0.338 - 242.5 1 2 2 0.0078 23 0 0 0 2.50E+08 2.57E+08 - - - 4.8456 1 221125_WJC_METTL3_EV_vs_WT_F08.19428.19428.4 2.96E-06 20/234 R.LPAGYTLHETPPAGASPVLTPQESQSALEAAAANGGQR[166.11]PR[166.11].E sp|P0C7T5|ATX1L_HUMAN 1 4030.0411 1.98 121320 19428 4 4030.040724 1008.5176 Ataxin-1-like OS=Homo sapiens OX=9606 GN=ATXN1L PE=1 SV=1 5.5 3231.7 - 195649 - - - -0.1047 - 3.451 0.529 - 95.5 1 2 0 -0.0004 40 0 0 0 5.75E+07 2.90E+07 - - - 4.1879 1 221125_WJC_METTL3_EV_vs_WT_F08.19432.19432.2 9.82E-06 22/26 K.NKLNDLEDALQQAK.E sp|P04264|K2C1_HUMAN 1 1598.8264 999 121321 19432 2 1598.828798 800.4205 "Keratin, type II cytoskeletal 1 OS=Homo sapiens OX=9606 GN=KRT1 PE=1 SV=6" 4.56 3232.3 - 1.42E+06 - - - 1.4999 - 3.941 0.661 - 1942 1 2 1 0.0024 14 0 0 0 4.78E+07 0.00E+00 - - - 7.3639 0.9979 221125_WJC_METTL3_EV_vs_WT_F08.19438.19438.3 0.00628 Oct-64 K.EIK[136.11]DTEK[136.11]EVDDLTAELK[136.11].S "sp|Q9NTJ3|SMC4_HUMAN,tr|E9PD53|E9PD53_HUMAN" 2 1999.0423 0.71 121325 19438 3 1999.041004 667.3547 Structural maintenance of chromosomes protein 4 OS=Homo sapiens OX=9606 GN=SMC4 PE=1 SV=2 4.2 3233 - 258786 - - - -0.6643 - 1.895 0.336 - 122.4 1 2 2 -0.0013 17 0 0 0 3.18E+06 4.47E+06 - - - 3.9006 1 221125_WJC_METTL3_EV_vs_WT_F08.19443.19443.3 5.88E-13 23/88 K.DFDFESANAQFNKEEIDREFHNK.L "sp|Q8ND56|LS14A_HUMAN,tr|A0A140TA76|A0A140TA76_HUMAN,tr|K7EMZ9|K7EMZ9_HUMAN" 3 2829.2631 0.97 121328 19443 3 2829.26378 944.095 Protein LSM14 homolog A OS=Homo sapiens OX=9606 GN=LSM14A PE=1 SV=3 4.43 3233.7 - 1.59E+06 - - - 0.2577 - 4.031 0.708 - 378.7 1 2 2 0.0007 23 0 0 0 2.50E+08 2.57E+08 - - - 9.7036 0.9998 221125_WJC_METTL3_EV_vs_WT_F08.19444.19444.4 0.000201 13/150 K.GYEEVHVPALK[136.11]PK[136.11]PFGSEEQLLPVEK[136.11].L "sp|O75643|U520_HUMAN,tr|A0A494C1A5|A0A494C1A5_HUMAN" 2 2943.5808 2.78 121329 19444 4 2943.590314 736.9025 U5 small nuclear ribonucleoprotein 200 kDa helicase OS=Homo sapiens OX=9606 GN=SNRNP200 PE=1 SV=2 5.02 3233.9 - 387478 - - - 3.2284 - 2.245 0.466 - 57.1 1 2 0 0.0095 26 0 0 0 2.47E+07 8.89E+06 - - - 3.5345 1 221125_WJC_METTL3_EV_vs_WT_F08.19449.19449.3 1.13E-11 20/80 K.AQQIHSQTSQQYPLYDLDLGK.F sp|P15924|DESP_HUMAN 1 2432.1972 0.95 121332 19449 3 2432.192672 811.7397 Desmoplakin OS=Homo sapiens OX=9606 GN=DSP PE=1 SV=3 5.21 3234.5 - 432678 - - - -1.8629 - 3.706 0.641 - 409.3 1 2 0 -0.0045 21 0 0 0 1.82E+07 1.92E+07 - - - 8.8258 1 221125_WJC_METTL3_EV_vs_WT_F08.19478.19478.4 1.39E-10 28/132 K.DFDFESANAQFNK[136.11]EEIDR[166.11]EFHNK[136.11].L "sp|Q8ND56|LS14A_HUMAN,tr|A0A140TA76|A0A140TA76_HUMAN,tr|K7EMZ9|K7EMZ9_HUMAN" 3 2855.2997 0.99 121348 19478 4 2855.293918 714.8322 Protein LSM14 homolog A OS=Homo sapiens OX=9606 GN=LSM14A PE=1 SV=3 4.43 3238.2 - 9.34E+07 - - - -2.0324 - 4.637 0.662 - 267 1 2 2 -0.0058 23 0 0 0 2.60E+09 2.61E+09 - - - 5.4835 1 221125_WJC_METTL3_EV_vs_WT_F08.19494.19494.4 1.03E-08 19/180 K.HISPAFQPPLPPTDGSTVVPAGPEPPPQSSR[166.11].A sp|Q68EM7|RHG17_HUMAN 1 3169.6072 2.43 121355 19494 4 3169.604046 793.4091 Rho GTPase-activating protein 17 OS=Homo sapiens OX=9606 GN=ARHGAP17 PE=1 SV=1 5.32 3240.4 - 399045 - - - -0.9897 - 3.415 0.544 - 118.1 1 2 0 -0.0031 31 0 0 0 2.08E+07 8.55E+06 - - - 4.3334 1 221125_WJC_METTL3_EV_vs_WT_F08.19502.19502.3 5.92E-11 25/120 K.HISPAFQPPLPPTDGSTVVPAGPEPPPQSSR.A sp|Q68EM7|RHG17_HUMAN 1 3159.5989 2.26 121360 19502 3 3159.591693 1054.2069 Rho GTPase-activating protein 17 OS=Homo sapiens OX=9606 GN=ARHGAP17 PE=1 SV=1 5.32 3241.4 - 624508 - - - -2.2851 - 3.863 0.588 - 330.9 1 2 0 -0.0072 31 0 0 0 3.05E+07 1.35E+07 - - - 8.2028 0.9999 221125_WJC_METTL3_EV_vs_WT_F08.19511.19511.3 9.64E-07 13/84 K.TKGHLDAELDAYMAQTDPETND.- "sp|Q9Y3Y2|CHTOP_HUMAN,tr|X6R700|X6R700_HUMAN" 2 2434.0594 1.74 121364 19511 3 2434.06192 812.3604 Chromatin target of PRMT1 protein OS=Homo sapiens OX=9606 GN=CHTOP PE=1 SV=2 4.1 3242.5 - 415292 - - - 1.0152 - 2.641 0.614 - 122.7 1 2 1 0.0025 22 0 0 0 1.41E+07 8.08E+06 - - - 7.6873 1 221125_WJC_METTL3_EV_vs_WT_F08.19526.19526.3 2.76E-07 Oct-44 R.FATSEELLSHLR[166.11].T "sp|Q9H7S9|ZN703_HUMAN,sp|Q96F45|ZN503_HUMAN" 2 1411.7335 1.49 121373 19526 3 1411.732364 471.5851 Zinc finger protein 703 OS=Homo sapiens OX=9606 GN=ZNF703 PE=1 SV=1 5.4 3244.5 - 157585 - - - -0.804 - 2.024 0.523 - 101.8 1 2 0 -0.0011 12 0 0 0 3.63E+06 2.44E+06 - - - 6.325 1 221125_WJC_METTL3_EV_vs_WT_F08.19533.19533.3 3.30E-06 Oct-44 R.FATSEELLSHLR.T "sp|Q9H7S9|ZN703_HUMAN,sp|Q96F45|ZN503_HUMAN" 2 1401.7252 1.49 121378 19533 3 1401.724744 468.249 Zinc finger protein 703 OS=Homo sapiens OX=9606 GN=ZNF703 PE=1 SV=1 5.4 3245.4 - 195805 - - - -0.346 - 2.237 0.491 - 74.5 1 2 0 -0.0005 12 0 0 0 3.63E+06 2.44E+06 - - - 6.2457 0.9999 221125_WJC_METTL3_EV_vs_WT_F08.19534.19534.2 6.57E-05 18-Nov K.FAAQELIEVK[136.11].R "sp|Q86U44|MTA70_HUMAN,tr|F5H6D8|F5H6D8_HUMAN,tr|H0YFV6|H0YFV6_HUMAN,tr|B4DTN4|B4DTN4_HUMAN" 4 1154.6427 0.02 121379 19534 2 1154.642834 578.3286 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 4.53 3245.6 - 462066 - - - 0.1377 - 2.106 0.468 - 289.5 1 2 0 0.0002 10 0 0 0 5.94E+06 2.77E+08 - - - 4.5765 1 221125_WJC_METTL3_EV_vs_WT_F08.19539.19539.3 1.31E-08 18/52 K.HTTSIFDDFAHYEK[136.11].R "sp|Q9BYJ9|YTHD1_HUMAN,sp|Q7Z739|YTHD3_HUMAN,tr|A0A087X0Q1|A0A087X0Q1_HUMAN,tr|A0A024R7W5|A0A024R7W5_HUMAN,tr|A0A087WY31|A0A087WY31_HUMAN" 5 1717.7828 1.43 121382 19539 3 1717.784966 573.6015 YTH domain-containing family protein 1 OS=Homo sapiens OX=9606 GN=YTHDF1 PE=1 SV=1 5.21 3246.2 - 1.37E+06 - - - 1.29 - 3.176 0.624 - 228.9 1 2 0 0.0022 14 0 0 0 2.86E+07 2.00E+07 - - - 8.5675 1 221125_WJC_METTL3_EV_vs_WT_F08.19541.19541.3 1.53E-10 19/120 K.HISPAFQPPLPPTDGSTVVPAGPEPPPQSSR[166.11].A sp|Q68EM7|RHG17_HUMAN 1 3169.6072 3.06 121384 19541 3 3169.605388 1057.543 Rho GTPase-activating protein 17 OS=Homo sapiens OX=9606 GN=ARHGAP17 PE=1 SV=1 5.32 3246.4 - 259494 - - - -0.5663 - 3.438 0.652 - 185.8 1 2 0 -0.0018 31 0 0 0 3.61E+07 1.18E+07 - - - 8.6497 1 221125_WJC_METTL3_EV_vs_WT_F08.19548.19548.4 4.24E-10 21/180 K.LVNTLNTIPSLGQSPGPVVVSNNSSAHGSQR[166.11].T "sp|Q7Z3K3|POGZ_HUMAN,tr|M0R2X2|M0R2X2_HUMAN,tr|H7C238|H7C238_HUMAN" 3 3139.625 0.6 121389 19548 4 3139.62443 785.9135 Pogo transposable element with ZNF domain OS=Homo sapiens OX=9606 GN=POGZ PE=1 SV=2 9.76 3247.3 - 397202 - - - -0.1685 - 3.628 0.535 - 245.5 1 2 0 -0.0005 31 0 0 0 3.39E+06 5.64E+06 - - - 4.2742 1 221125_WJC_METTL3_EV_vs_WT_F08.19549.19549.4 5.32E-06 14/78 K.HTTSIFDDFAHYEK.R "sp|Q9BYJ9|YTHD1_HUMAN,sp|Q7Z739|YTHD3_HUMAN,tr|A0A087X0Q1|A0A087X0Q1_HUMAN,tr|A0A024R7W5|A0A024R7W5_HUMAN,tr|A0A087WY31|A0A087WY31_HUMAN" 5 1709.7686 1.42 121390 19549 4 1709.769121 428.4494 YTH domain-containing family protein 1 OS=Homo sapiens OX=9606 GN=YTHDF1 PE=1 SV=1 5.21 3247.4 - 378347 - - - 0.334 - 2.668 0.625 - 103.9 1 2 0 0.0006 14 0 0 0 6.56E+06 4.63E+06 - - - 5.023 0.9999 221125_WJC_METTL3_EV_vs_WT_F08.19550.19550.4 4.55E-05 Nov-84 K.AQNDLIWNIK[136.11]DELK[136.11]K[136.11].V "sp|P09874|PARP1_HUMAN,tr|A0A7I2V5E9|A0A7I2V5E9_HUMAN,tr|A0A7I2V625|A0A7I2V625_HUMAN,tr|A0A7I2V3E1|A0A7I2V3E1_HUMAN" 4 1851.0316 0.8 121391 19550 4 1851.033188 463.7652 Poly [ADP-ribose] polymerase 1 OS=Homo sapiens OX=9606 GN=PARP1 PE=1 SV=4 6.16 3247.6 - 235080 - - - 0.832 - 2.324 0.572 - 107.6 1 2 1 0.0015 15 0 0 0 2.81E+06 3.50E+06 - - - 4.506 0.9972 221125_WJC_METTL3_EV_vs_WT_F08.19558.19558.4 0.0145 Sep-90 K.EK[136.11]YQEEFEHFQQELDK[136.11].K sp|P49257|LMAN1_HUMAN 1 2141.9877 1.27 121397 19558 4 2141.992476 536.5042 Protein ERGIC-53 OS=Homo sapiens OX=9606 GN=LMAN1 PE=1 SV=2 4.41 3248.7 - 235583 - - - 2.246 - 1.56 0.356 - 34.7 1 2 1 0.0048 16 0 0 0 8.79E+06 6.93E+06 - - - 2.4799 1 221125_WJC_METTL3_EV_vs_WT_F08.19560.19560.4 2.24E-12 28/150 R.LEKEIETYHNLLEGGQEDFESSGAGK.L "sp|P35527|K1C9_HUMAN,tr|K7EQQ3|K7EQQ3_HUMAN" 2 2879.3461 595.53 121398 19560 4 2879.349713 720.8438 "Keratin, type I cytoskeletal 9 OS=Homo sapiens OX=9606 GN=KRT9 PE=1 SV=3" 4.3 3249 - 2.97E+07 - - - 1.2506 - 4.85 0.696 - 596.7 1 2 1 0.0036 26 0 0 0 3.33E+08 5.59E+05 - - - 5.7811 1 221125_WJC_METTL3_EV_vs_WT_F08.19564.19564.3 2.62E-12 19/52 K.HTTSIFDDFAHYEK.R "sp|Q9BYJ9|YTHD1_HUMAN,sp|Q7Z739|YTHD3_HUMAN,tr|A0A087X0Q1|A0A087X0Q1_HUMAN,tr|A0A024R7W5|A0A024R7W5_HUMAN,tr|A0A087WY31|A0A087WY31_HUMAN" 5 1709.7686 1.43 121401 19564 3 1709.770028 570.9301 YTH domain-containing family protein 1 OS=Homo sapiens OX=9606 GN=YTHDF1 PE=1 SV=1 5.21 3249.4 - 1.77E+06 - - - 0.8644 - 3.561 0.668 - 362.7 1 2 0 0.0015 14 0 0 0 2.86E+07 2.00E+07 - - - 9.3623 0.8137 221125_WJC_METTL3_EV_vs_WT_F08.19566.19566.3 0.000146 Nov-64 K.R[166.11]R[166.11]AEQDSTTVAAFASSL.V "sp|Q86U44|MTA70_HUMAN,tr|F5H6D8|F5H6D8_HUMAN,tr|H0YFV6|H0YFV6_HUMAN,tr|B4DTN4|B4DTN4_HUMAN" 4 1828.9182 0.001 121403 19566 3 1828.917441 610.6467 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 6.07 3249.6 - 546833 - - - -0.4314 - 2.096 0.31 - 146.3 1 1 1 -0.0008 17 0 0 0 0.00E+00 1.27E+07 - - - 3.8655 1 221125_WJC_METTL3_EV_vs_WT_F08.19568.19568.4 1.66E-07 16/78 K.HTTSIFDDFAHYEK[136.11].R "sp|Q9BYJ9|YTHD1_HUMAN,sp|Q7Z739|YTHD3_HUMAN,tr|A0A087X0Q1|A0A087X0Q1_HUMAN,tr|A0A024R7W5|A0A024R7W5_HUMAN,tr|A0A087WY31|A0A087WY31_HUMAN" 5 1717.7828 1.44 121405 19568 4 1717.782085 430.453 YTH domain-containing family protein 1 OS=Homo sapiens OX=9606 GN=YTHDF1 PE=1 SV=1 5.21 3249.9 - 488976 - - - -0.3871 - 2.845 0.616 - 124.4 1 2 0 -0.0007 14 0 0 0 6.56E+06 4.55E+06 - - - 4.968 0.9999 221125_WJC_METTL3_EV_vs_WT_F08.19574.19574.4 1.58E-18 28/138 R.KAPLNIPGTPVLEDFPQNDDEKER.L "sp|Q15003|CND2_HUMAN,tr|C9J470|C9J470_HUMAN,tr|C9JZP1|C9JZP1_HUMAN,tr|E9PHA2|E9PHA2_HUMAN" 4 2721.361 1.41 121409 19574 4 2721.36368 681.3475 Condensin complex subunit 2 OS=Homo sapiens OX=9606 GN=NCAPH PE=1 SV=3 4.3 3250.6 - 1.23E+06 - - - 0.9944 - 4.844 0.587 - 599.2 1 2 1 0.0027 24 0 0 0 5.18E+07 3.68E+07 - - - 4.8409 1 221125_WJC_METTL3_EV_vs_WT_F08.19575.19575.4 1.65E-09 21/138 R.K[136.11]APLNIPGTPVLEDFPQNDDEK[136.11]ER[166.11].L "sp|Q15003|CND2_HUMAN,tr|C9J470|C9J470_HUMAN,tr|C9JZP1|C9JZP1_HUMAN,tr|E9PHA2|E9PHA2_HUMAN" 4 2747.3976 1.41 121410 19575 4 2747.396216 687.8567 Condensin complex subunit 2 OS=Homo sapiens OX=9606 GN=NCAPH PE=1 SV=3 4.3 3250.7 - 787034 - - - -0.5198 - 3.999 0.619 - 259.2 1 2 1 -0.0014 24 0 0 0 5.19E+07 3.69E+07 - - - 5.0583 1 221125_WJC_METTL3_EV_vs_WT_F08.19580.19580.4 0.000312 14/78 K.K[136.11]DDEENYLDLFSHK[136.11].N sp|Q07666|KHDR1_HUMAN 1 1767.8286 1.05 121415 19580 4 1767.825719 442.9644 "KH domain-containing, RNA-binding, signal transduction-associated protein 1 OS=Homo sapiens OX=9606 GN=KHDRBS1 PE=1 SV=1" 4.43 3251.4 - 302568 - - - -1.6551 - 2.237 0.521 - 170 1 2 0 -0.0029 14 0 0 0 1.04E+07 9.93E+06 - - - 4.053 0.9997 221125_WJC_METTL3_EV_vs_WT_F08.19581.19581.3 0.000435 Aug-52 K.K[136.11]GPGEVAGTVTGQK[136.11].R "sp|Q86U44|MTA70_HUMAN,tr|F5H6D8|F5H6D8_HUMAN,tr|H0YFV6|H0YFV6_HUMAN,tr|B4DTN4|B4DTN4_HUMAN" 4 1343.738 0.001 121416 19581 3 1343.738597 448.9199 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 8.59 3251.5 - 145322 - - - 0.4599 - 1.789 0.378 - 110.9 1 2 0 0.0006 14 0 0 0 0.00E+00 9.68E+06 - - - 4.2999 1 221125_WJC_METTL3_EV_vs_WT_F08.19584.19584.3 9.48E-12 20/72 L.SSASTSSHNLQSIFNIGSR[166.11].G "sp|P43243|MATR3_HUMAN,tr|A8MXP9|A8MXP9_HUMAN,tr|D6R991|D6R991_HUMAN,tr|D6REK4|D6REK4_HUMAN,tr|A0A0R4J2E8|A0A0R4J2E8_HUMAN,tr|D6RCM3|D6RCM3_HUMAN,tr|D6R8Z5|D6R8Z5_HUMAN,tr|D6REM6|D6REM6_HUMAN" 8 2001.9744 1.3 121417 19584 3 2001.974303 668.3321 Matrin-3 OS=Homo sapiens OX=9606 GN=MATR3 PE=1 SV=2 9.49 3251.9 - 1.12E+06 - - - -0.024 - 3.519 0.644 - 389.6 1 1 0 0 19 0 0 0 3.46E+08 2.65E+08 - - - 8.811 1 221125_WJC_METTL3_EV_vs_WT_F08.19586.19586.3 1.83E-10 24/72 L.SSASTSSHNLQSIFNIGSR.G "sp|P43243|MATR3_HUMAN,tr|A8MXP9|A8MXP9_HUMAN,tr|D6R991|D6R991_HUMAN,tr|D6REK4|D6REK4_HUMAN,tr|A0A0R4J2E8|A0A0R4J2E8_HUMAN,tr|D6RCM3|D6RCM3_HUMAN,tr|D6R8Z5|D6R8Z5_HUMAN,tr|D6REM6|D6REM6_HUMAN" 8 1991.9661 1.3 121419 19586 3 1991.966654 664.996 Matrin-3 OS=Homo sapiens OX=9606 GN=MATR3 PE=1 SV=2 9.49 3252.1 - 1.14E+06 - - - 0.2877 - 4.039 0.705 - 766.3 1 1 0 0.0006 19 0 0 0 3.46E+08 2.65E+08 - - - 9.8296 1 221125_WJC_METTL3_EV_vs_WT_F08.19587.19587.3 2.41E-07 16/52 K.K[136.11]DDEENYLDLFSHK[136.11].N sp|Q07666|KHDR1_HUMAN 1 1767.8286 1.14 121420 19587 3 1767.828938 590.2835 "KH domain-containing, RNA-binding, signal transduction-associated protein 1 OS=Homo sapiens OX=9606 GN=KHDRBS1 PE=1 SV=1" 4.43 3252.3 - 1.09E+06 - - - 0.1657 - 2.922 0.635 - 293.9 1 2 0 0.0003 14 0 0 0 2.30E+07 2.03E+07 - - - 8.4691 1 221125_WJC_METTL3_EV_vs_WT_F08.19588.19588.3 4.60E-11 17/52 K.KDDEENYLDLFSHK.N sp|Q07666|KHDR1_HUMAN 1 1751.8002 1.13 121421 19588 3 1751.80159 584.9407 "KH domain-containing, RNA-binding, signal transduction-associated protein 1 OS=Homo sapiens OX=9606 GN=KHDRBS1 PE=1 SV=1" 4.43 3252.4 - 1.06E+06 - - - 0.7678 - 3.166 0.627 - 347.6 1 2 0 0.0013 14 0 0 0 2.30E+07 2.04E+07 - - - 8.5928 0.9999 221125_WJC_METTL3_EV_vs_WT_F08.19589.19589.4 9.84E-07 18/102 R.HLQLAIR[166.11]NDEELNK[136.11]LLGK[136.11].V "sp|Q9BTM1|H2AJ_HUMAN,sp|Q99878|H2A1J_HUMAN,sp|Q16777|H2A2C_HUMAN,sp|P20671|H2A1D_HUMAN,sp|P0C0S8|H2A1_HUMAN,sp|Q6FI13|H2A2A_HUMAN,sp|Q96KK5|H2A1H_HUMAN,tr|A0A0U1RR32|A0A0U1RR32_HUMAN,tr|A0A0U1RRH7|A0A0U1RRH7_HUMAN,tr|H0YFX9|H0YFX9_HUMAN" 10 2129.2167 1.06 121422 19589 4 2129.217716 533.3115 Histone H2A.J OS=Homo sapiens OX=9606 GN=H2AJ PE=1 SV=1 6.76 3252.5 - 747438 - - - 0.4739 - 2.919 0.544 - 277.8 1 2 2 0.001 18 0 0 0 1.37E+07 1.29E+07 - - - 4.3277 0.9999 221125_WJC_METTL3_EV_vs_WT_F08.19590.19590.4 1.04E-10 18/102 R.HLQLAIRNDEELNKLLGK.V "sp|Q9BTM1|H2AJ_HUMAN,sp|Q99878|H2A1J_HUMAN,sp|Q16777|H2A2C_HUMAN,sp|P20671|H2A1D_HUMAN,sp|P0C0S8|H2A1_HUMAN,sp|Q6FI13|H2A2A_HUMAN,sp|Q96KK5|H2A1H_HUMAN,tr|A0A0U1RR32|A0A0U1RR32_HUMAN,tr|A0A0U1RRH7|A0A0U1RRH7_HUMAN,tr|H0YFX9|H0YFX9_HUMAN" 10 2103.18 0.85 121423 19590 4 2103.18295 526.8023 Histone H2A.J OS=Homo sapiens OX=9606 GN=H2AJ PE=1 SV=1 6.76 3252.6 - 647012 - - - 1.385 - 3.642 0.592 - 268.8 1 2 2 0.0029 18 0 0 0 1.48E+07 1.74E+07 - - - 4.8207 1 221125_WJC_METTL3_EV_vs_WT_F08.19597.19597.4 2.14E-07 17/78 K.KDDEENYLDLFSHK.N sp|Q07666|KHDR1_HUMAN 1 1751.8002 1.05 121428 19597 4 1751.80233 438.9573 "KH domain-containing, RNA-binding, signal transduction-associated protein 1 OS=Homo sapiens OX=9606 GN=KHDRBS1 PE=1 SV=1" 4.43 3253.5 - 657854 - - - 1.1902 - 2.888 0.584 - 255.4 1 2 0 0.0021 14 0 0 0 1.04E+07 9.93E+06 - - - 4.6945 1 221125_WJC_METTL3_EV_vs_WT_F08.19599.19599.3 1.53E-05 15/128 R.SDSPVPTAPTSGGPK[136.11]PSTASAVPELATDPELEK[136.11].K "sp|Q86U44|MTA70_HUMAN,tr|B4E349|B4E349_HUMAN,tr|F5H6D8|F5H6D8_HUMAN,tr|B4DTN4|B4DTN4_HUMAN" 4 3248.6271 0.001 121430 19599 3 3248.62755 1083.883 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 4.18 3253.7 - 667701 - - - 0.1391 - 2.824 0.544 - 92.1 1 2 0 0.0005 33 0 0 0 0.00E+00 1.88E+07 - - - 6.9934 1 221125_WJC_METTL3_EV_vs_WT_F08.19604.19604.4 3.27E-08 11/168 R.K[136.11]VPGVTAIDLDEDTC[160.03]TFHIYGEDQDAVK[136.11]K[136.11].A "sp|Q06787|FMR1_HUMAN,tr|A0A087WY29|A0A087WY29_HUMAN,tr|R9WNI0|R9WNI0_HUMAN,tr|A8MQB8|A8MQB8_HUMAN,tr|A0A087WWR6|A0A087WWR6_HUMAN,tr|A0A087WXI3|A0A087WXI3_HUMAN,tr|Q8IXW7|Q8IXW7_HUMAN,tr|G3V0J0|G3V0J0_HUMAN" 8 3287.6082 1.38 121433 19604 4 3287.607927 822.9093 Synaptic functional regulator FMR1 OS=Homo sapiens OX=9606 GN=FMR1 PE=1 SV=1 4.32 3254.4 - 457553 - - - -0.0903 - 3.041 0.639 - 55.7 1 2 0 -0.0003 29 0 0 0 9.96E+06 7.21E+06 - - - 5.1305 1 221125_WJC_METTL3_EV_vs_WT_F08.19606.19606.4 1.31E-08 25/168 R.KVPGVTAIDLDEDTC[160.03]TFHIYGEDQDAVKK.A "sp|Q06787|FMR1_HUMAN,tr|A0A087WY29|A0A087WY29_HUMAN,tr|R9WNI0|R9WNI0_HUMAN,tr|A8MQB8|A8MQB8_HUMAN,tr|A0A087WWR6|A0A087WWR6_HUMAN,tr|A0A087WXI3|A0A087WXI3_HUMAN,tr|Q8IXW7|Q8IXW7_HUMAN,tr|G3V0J0|G3V0J0_HUMAN" 8 3263.5656 1.36 121435 19606 4 3263.566999 816.8987 Synaptic functional regulator FMR1 OS=Homo sapiens OX=9606 GN=FMR1 PE=1 SV=1 4.32 3254.7 - 741880 - - - 0.4213 - 4.561 0.68 - 382.7 1 2 0 0.0014 29 0 0 0 9.96E+06 7.32E+06 - - - 5.612 1 221125_WJC_METTL3_EV_vs_WT_F08.19611.19611.3 5.08E-16 26/116 K.DSAHLMNGPISQTTSQTSSIPPLSQVPATK.V "sp|Q92615|LAR4B_HUMAN,tr|B5MCU2|B5MCU2_HUMAN,tr|X6RCG6|X6RCG6_HUMAN" 3 3092.5448 1.38 121440 19611 3 3092.556959 1031.8556 La-related protein 4B OS=Homo sapiens OX=9606 GN=LARP4B PE=1 SV=3 6.74 3255.3 - 454320 - - - 3.9223 - 3.998 0.763 - 357.2 1 2 0 0.0121 30 0 0 0 3.32E+08 2.41E+08 - - - 10.2315 0.9999 221125_WJC_METTL3_EV_vs_WT_F08.19623.19623.4 0.000531 Dec-84 R.STSHK[136.11]PDEIYGMIER[166.11].L sp|Q86U44|MTA70_HUMAN 1 1779.8581 0.01 121448 19623 4 1779.857792 445.9718 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 5.42 3256.9 - 252526 - - - -0.1472 - 2.053 0.454 - 71.9 1 2 0 -0.0003 15 0 0 0 3.62E+04 6.17E+06 - - - 3.4349 1 221125_WJC_METTL3_EV_vs_WT_F08.19627.19627.3 8.12E-19 24/116 K.DSAHLMNGPISQTTSQTSSIPPLSQVPATK[136.11].V "sp|Q92615|LAR4B_HUMAN,tr|B5MCU2|B5MCU2_HUMAN,tr|X6RCG6|X6RCG6_HUMAN" 3 3100.559 1.38 121451 19627 3 3100.562884 1034.527 La-related protein 4B OS=Homo sapiens OX=9606 GN=LARP4B PE=1 SV=3 6.74 3257.4 - 1.14E+06 - - - 1.2433 - 4.397 0.709 - 236.4 1 2 0 0.0039 30 0 0 0 3.32E+08 2.41E+08 - - - 9.8506 1 221125_WJC_METTL3_EV_vs_WT_F08.19629.19629.4 1.20E-10 17/174 K.DSAHLMNGPISQTTSQTSSIPPLSQVPATK.V "sp|Q92615|LAR4B_HUMAN,tr|B5MCU2|B5MCU2_HUMAN,tr|X6RCG6|X6RCG6_HUMAN" 3 3092.5448 1.5 121452 19629 4 3092.549471 774.1435 La-related protein 4B OS=Homo sapiens OX=9606 GN=LARP4B PE=1 SV=3 6.74 3257.6 - 534330 - - - 1.501 - 2.833 0.577 - 81.3 1 2 0 0.0046 30 0 0 0 8.77E+07 5.83E+07 - - - 4.5656 0.9998 221125_WJC_METTL3_EV_vs_WT_F08.19630.19630.4 0.0106 15/174 K.DSAHLMNGPISQTTSQTSSIPPLSQVPATK[136.11].V "sp|Q92615|LAR4B_HUMAN,tr|B5MCU2|B5MCU2_HUMAN,tr|X6RCG6|X6RCG6_HUMAN" 3 3100.559 1.5 121453 19630 4 3100.56786 776.147 La-related protein 4B OS=Homo sapiens OX=9606 GN=LARP4B PE=1 SV=3 6.74 3257.7 - 404832 - - - 2.8482 - 1.899 0.459 - 65 1 2 0 0.0088 30 0 0 0 8.77E+07 5.83E+07 - - - 3.4149 1 221125_WJC_METTL3_EV_vs_WT_F08.19638.19638.2 1.31E-14 18/36 L.SSASTSSHNLQSIFNIGSR.G "sp|P43243|MATR3_HUMAN,tr|A8MXP9|A8MXP9_HUMAN,tr|D6R991|D6R991_HUMAN,tr|D6REK4|D6REK4_HUMAN,tr|A0A0R4J2E8|A0A0R4J2E8_HUMAN,tr|D6RCM3|D6RCM3_HUMAN,tr|D6R8Z5|D6R8Z5_HUMAN,tr|D6REM6|D6REM6_HUMAN" 8 1991.9661 1.47 121458 19638 2 1991.973867 996.9903 Matrin-3 OS=Homo sapiens OX=9606 GN=MATR3 PE=1 SV=2 9.49 3258.8 - 364889 - - - 3.9087 - 3.509 0.684 - 776.3 1 1 0 0.0078 19 0 0 0 5.17E+06 3.51E+06 - - - 7.1769 0.9999 221125_WJC_METTL3_EV_vs_WT_F08.19659.19659.3 2.42E-09 16/84 R.EQQIVIQSSGGLSKDDIENMVK.N "sp|P38646|GRP75_HUMAN,tr|A0A7I2V2S7|A0A7I2V2S7_HUMAN,tr|A0A7I2V2G2|A0A7I2V2G2_HUMAN,tr|H0Y8S0|H0Y8S0_HUMAN,tr|A0A7I2V3F7|A0A7I2V3F7_HUMAN,tr|A0A7I2YQB2|A0A7I2YQB2_HUMAN,tr|D6RCD7|D6RCD7_HUMAN" 7 2417.2108 0.28 121474 19659 3 2417.213981 806.7442 "Stress-70 protein, mitochondrial OS=Homo sapiens OX=9606 GN=HSPA9 PE=1 SV=2" 4.32 3261.5 - 367912 - - - 1.3139 - 3.005 0.637 - 161 1 2 1 0.0032 22 0 0 0 4.58E+06 1.66E+07 - - - 8.2496 0.968 221125_WJC_METTL3_EV_vs_WT_F08.19663.19663.3 0.418 Jul-92 R.K[136.11]APLNIPGTPVLEDFPQNDDEK[136.11]ER[166.11].L "sp|Q15003|CND2_HUMAN,tr|C9J470|C9J470_HUMAN,tr|C9JZP1|C9JZP1_HUMAN,tr|E9PHA2|E9PHA2_HUMAN" 4 2747.3976 2.22 121478 19663 3 2747.396152 916.8065 Condensin complex subunit 2 OS=Homo sapiens OX=9606 GN=NCAPH PE=1 SV=3 4.3 3262 - 135152 - - - -0.5431 - 1.369 0.246 - 30.4 1 2 1 -0.0015 24 0 0 0 3.34E+06 1.50E+06 - - - 2.0117 1 221125_WJC_METTL3_EV_vs_WT_F08.19671.19671.2 8.30E-08 Dec-32 K.GILFVGSGVSGGEEGAR[166.11].Y "sp|P52209|6PGD_HUMAN,tr|K7EMN2|K7EMN2_HUMAN,tr|K7EPF6|K7EPF6_HUMAN,tr|K7EM49|K7EM49_HUMAN" 4 1600.8085 0.07 121483 19671 2 1600.81507 801.4115 "6-phosphogluconate dehydrogenase, decarboxylating OS=Homo sapiens OX=9606 GN=PGD PE=1 SV=3" 4.53 3263.1 - 278276 - - - 4.1323 - 2.714 0.59 - 339.3 1 2 0 0.0066 17 0 0 0 2.83E+05 3.95E+06 - - - 5.8513 0.9997 221125_WJC_METTL3_EV_vs_WT_F08.19673.19673.3 6.42E-06 17/84 R.EQQIVIQSSGGLSK[136.11]DDIENMVK[136.11].N "sp|P38646|GRP75_HUMAN,tr|A0A7I2V2S7|A0A7I2V2S7_HUMAN,tr|A0A7I2V2G2|A0A7I2V2G2_HUMAN,tr|H0Y8S0|H0Y8S0_HUMAN,tr|A0A7I2V3F7|A0A7I2V3F7_HUMAN,tr|A0A7I2YQB2|A0A7I2YQB2_HUMAN,tr|D6RCD7|D6RCD7_HUMAN" 7 2433.2392 0.32 121484 19673 3 2433.246956 812.087 "Stress-70 protein, mitochondrial OS=Homo sapiens OX=9606 GN=HSPA9 PE=1 SV=2" 4.32 3263.4 - 510869 - - - 3.1855 - 3.468 0.547 - 218.2 1 2 1 0.0078 22 0 0 0 4.58E+06 1.42E+07 - - - 7.5847 1 221125_WJC_METTL3_EV_vs_WT_F08.19675.19675.3 6.76E-10 19/80 K.ADRDESSPYAAMLAAQDVAQR.C "sp|P62263|RS14_HUMAN,tr|A0A2R8Y811|A0A2R8Y811_HUMAN,tr|E5RH77|E5RH77_HUMAN" 3 2264.0492 1.63 121486 19675 3 2264.055028 755.6903 40S ribosomal protein S14 OS=Homo sapiens OX=9606 GN=RPS14 PE=1 SV=3 4.23 3263.6 - 282219 - - - 2.5923 - 3.959 0.659 - 495.6 1 2 1 0.0059 21 0 0 0 2.93E+07 1.80E+07 - - - 9.1844 0.9997 221125_WJC_METTL3_EV_vs_WT_F08.19684.19684.4 0.000153 15/120 R.SK[136.11]LAAAILGGVDQIHIK[136.11]PGAK[136.11].V "sp|P22087|FBRL_HUMAN,tr|M0R299|M0R299_HUMAN,tr|M0R0P1|M0R0P1_HUMAN,tr|M0R1H0|M0R1H0_HUMAN,tr|M0QXL5|M0QXL5_HUMAN,tr|M0R2Q4|M0R2Q4_HUMAN,tr|M0R2B0|M0R2B0_HUMAN,tr|M0R2U2|M0R2U2_HUMAN" 8 2110.2689 0.82 121493 19684 4 2110.2686 528.5745 rRNA 2'-O-methyltransferase fibrillarin OS=Homo sapiens OX=9606 GN=FBL PE=1 SV=2 9.7 3264.8 - 166185 - - - -0.1227 - 2.658 0.452 - 184.1 1 2 1 -0.0003 21 0 0 0 1.88E+06 2.30E+06 - - - 3.4834 0.9999 221125_WJC_METTL3_EV_vs_WT_F08.19688.19688.4 6.91E-09 17/138 K.ENALVQMADGNQAQLAMSHLNGHK.L "sp|P26599|PTBP1_HUMAN,tr|A0A0U1RRM4|A0A0U1RRM4_HUMAN,tr|A6NLN1|A6NLN1_HUMAN,tr|A0A0D9SF20|A0A0D9SF20_HUMAN,tr|A0A7I2V621|A0A7I2V621_HUMAN,tr|K7EK45|K7EK45_HUMAN" 6 2576.2224 1.05 121495 19688 4 2576.232265 645.0629 Polypyrimidine tract-binding protein 1 OS=Homo sapiens OX=9606 GN=PTBP1 PE=1 SV=1 6 3265.4 - 541210 - - - 3.8335 - 3.593 0.577 - 238.7 1 2 0 0.0099 24 0 0 0 3.92E+07 3.74E+07 - - - 4.656 1 221125_WJC_METTL3_EV_vs_WT_F08.19692.19692.4 8.77E-08 23/138 K.ENALVQMADGNQAQLAMSHLNGHK[136.11].L "sp|P26599|PTBP1_HUMAN,tr|A0A0U1RRM4|A0A0U1RRM4_HUMAN,tr|A6NLN1|A6NLN1_HUMAN,tr|A0A0D9SF20|A0A0D9SF20_HUMAN,tr|A0A7I2V621|A0A7I2V621_HUMAN,tr|K7EK45|K7EK45_HUMAN" 6 2584.2366 1.05 121497 19692 4 2584.242988 647.0664 Polypyrimidine tract-binding protein 1 OS=Homo sapiens OX=9606 GN=PTBP1 PE=1 SV=1 6 3265.9 - 757922 - - - 2.4762 - 3.762 0.56 - 383.7 1 2 0 0.0064 24 0 0 0 3.81E+07 3.62E+07 - - - 4.5237 1 221125_WJC_METTL3_EV_vs_WT_F08.19693.19693.3 2.48E-09 19/80 K.ADR[166.11]DESSPYAAMLAAQDVAQR[166.11].C "sp|P62263|RS14_HUMAN,tr|A0A2R8Y811|A0A2R8Y811_HUMAN,tr|E5RH77|E5RH77_HUMAN" 3 2284.0657 1.62 121498 19693 3 2284.073175 762.3625 40S ribosomal protein S14 OS=Homo sapiens OX=9606 GN=RPS14 PE=1 SV=3 4.23 3266 - 426972 - - - 3.2731 - 4.098 0.657 - 503.9 1 2 1 0.0075 21 0 0 0 2.92E+07 1.80E+07 - - - 9.2444 0.9998 221125_WJC_METTL3_EV_vs_WT_F08.19694.19694.4 0.00279 17/138 K.LATDKNDPHLC[160.03]DFIETHYLNEQVK.A "sp|P02794|FRIH_HUMAN,tr|G3V1D1|G3V1D1_HUMAN,tr|G3V192|G3V192_HUMAN" 3 2899.3811 1.36 121499 19694 4 2899.386469 725.8525 Ferritin heavy chain OS=Homo sapiens OX=9606 GN=FTH1 PE=1 SV=2 4.8 3266.2 - 410158 - - - 1.8663 - 3.566 0.501 - 121.8 1 2 1 0.0054 24 0 0 0 7.01E+06 5.17E+06 - - - 3.9933 0.9998 221125_WJC_METTL3_EV_vs_WT_F08.19695.19695.4 9.88E-05 14/126 K.RVIISAPSADAPMFVMGVNHEK.Y "sp|P04406|G3P_HUMAN,tr|E7EUT5|E7EUT5_HUMAN" 2 2368.2032 1.2 121500 19695 4 2368.209353 593.0581 Glyceraldehyde-3-phosphate dehydrogenase OS=Homo sapiens OX=9606 GN=GAPDH PE=1 SV=3 6.75 3266.3 - 238371 - - - 2.6163 - 2.966 0.438 - 109.2 1 2 0 0.0062 22 0 0 0 6.67E+06 5.54E+06 - - - 3.3924 0.9931 221125_WJC_METTL3_EV_vs_WT_F08.19697.19697.4 3.59E-05 13/120 R.SKLAAAILGGVDQIHIKPGAK.V "sp|P22087|FBRL_HUMAN,tr|M0R299|M0R299_HUMAN,tr|M0R0P1|M0R0P1_HUMAN,tr|M0R1H0|M0R1H0_HUMAN,tr|M0QXL5|M0QXL5_HUMAN,tr|M0R2Q4|M0R2Q4_HUMAN,tr|M0R2B0|M0R2B0_HUMAN,tr|M0R2U2|M0R2U2_HUMAN" 8 2086.2263 0.82 121502 19697 4 2086.236173 522.5638 rRNA 2'-O-methyltransferase fibrillarin OS=Homo sapiens OX=9606 GN=FBL PE=1 SV=2 9.7 3266.6 - 128636 - - - 4.7521 - 2.332 0.396 - 115.8 1 2 1 0.0099 21 0 0 0 1.88E+06 2.30E+06 - - - 2.95 0.9994 221125_WJC_METTL3_EV_vs_WT_F08.19706.19706.4 1.71E-09 18/96 K.GKFGHEFLEFEFRPDGK.L "sp|Q96A72|MGN2_HUMAN,sp|P61326|MGN_HUMAN,tr|F5H6N1|F5H6N1_HUMAN" 3 2038.9901 1.6 121507 19706 4 2038.999716 510.7548 Protein mago nashi homolog 2 OS=Homo sapiens OX=9606 GN=MAGOHB PE=1 SV=1 5.53 3267.6 - 284043 - - - 4.7107 - 3.885 0.591 - 231.4 1 2 1 0.0096 17 0 0 0 2.25E+07 1.40E+07 - - - 4.8386 0.9997 221125_WJC_METTL3_EV_vs_WT_F08.19709.19709.4 1.87E-06 18/96 K.GK[136.11]FGHEFLEFEFR[166.11]PDGK[136.11].L "sp|Q96A72|MGN2_HUMAN,sp|P61326|MGN_HUMAN,tr|F5H6N1|F5H6N1_HUMAN" 3 2065.0268 1.6 121510 19709 4 2065.034076 517.264 Protein mago nashi homolog 2 OS=Homo sapiens OX=9606 GN=MAGOHB PE=1 SV=1 5.53 3268 - 237323 - - - 3.5326 - 3.381 0.558 - 248.5 1 2 1 0.0073 17 0 0 0 2.27E+07 1.41E+07 - - - 4.5038 0.9934 221125_WJC_METTL3_EV_vs_WT_F08.19714.19714.4 8.65E-07 17/174 H.QVVSSDFNSDTHSSTFDAGAGIALNDHFVK[136.11].L "sp|P04406|G3P_HUMAN,tr|E7EUT5|E7EUT5_HUMAN" 2 3173.4781 1.99 121512 19714 4 3173.487842 794.3768 Glyceraldehyde-3-phosphate dehydrogenase OS=Homo sapiens OX=9606 GN=GAPDH PE=1 SV=3 4.54 3268.8 - 737666 - - - 3.0585 - 3.212 0.579 - 149.6 1 1 0 0.0097 30 0 0 0 2.50E+07 1.26E+07 - - - 4.62 1 221125_WJC_METTL3_EV_vs_WT_F08.19715.19715.4 2.40E-12 30/156 R.IKEETEIIEGEVVEIQIDRPATGTGSK.V "sp|Q9Y230|RUVB2_HUMAN,tr|M0R0Y3|M0R0Y3_HUMAN,tr|X6R2L4|X6R2L4_HUMAN" 3 2940.5292 1.09 121513 19715 4 2940.544334 736.1396 RuvB-like 2 OS=Homo sapiens OX=9606 GN=RUVBL2 PE=1 SV=3 4.31 3268.9 - 532281 - - - 5.1596 - 5.908 0.661 - 627.9 1 2 1 0.0152 27 0 0 0 1.39E+07 1.28E+07 - - - 5.5309 1 221125_WJC_METTL3_EV_vs_WT_F08.19716.19716.3 5.86E-11 17/92 K.ENALVQMADGNQAQLAMSHLNGHK.L "sp|P26599|PTBP1_HUMAN,tr|A0A0U1RRM4|A0A0U1RRM4_HUMAN,tr|A6NLN1|A6NLN1_HUMAN,tr|A0A0D9SF20|A0A0D9SF20_HUMAN,tr|A0A7I2V621|A0A7I2V621_HUMAN,tr|K7EK45|K7EK45_HUMAN" 6 2576.2224 0.87 121514 19716 3 2576.224862 859.7481 Polypyrimidine tract-binding protein 1 OS=Homo sapiens OX=9606 GN=PTBP1 PE=1 SV=1 6 3269 - 255281 - - - 0.9599 - 3.34 0.657 - 247.4 1 2 0 0.0025 24 0 0 0 5.30E+06 6.10E+06 - - - 8.6652 0.9999 221125_WJC_METTL3_EV_vs_WT_F08.19717.19717.3 5.41E-06 11/104 R.IK[136.11]EETEIIEGEVVEIQIDR[166.11]PATGTGSK[136.11].V "sp|Q9Y230|RUVB2_HUMAN,tr|M0R0Y3|M0R0Y3_HUMAN,tr|X6R2L4|X6R2L4_HUMAN" 3 2966.5658 1.04 121515 19717 3 2966.561374 989.8626 RuvB-like 2 OS=Homo sapiens OX=9606 GN=RUVBL2 PE=1 SV=3 4.31 3269.1 - 102994 - - - -1.5027 - 3.013 0.535 - 92.8 1 2 1 -0.0045 27 0 0 0 2.30E+06 2.21E+06 - - - 7.0409 0.9997 221125_WJC_METTL3_EV_vs_WT_F08.19720.19720.4 1.40E-08 21/114 K.HYFQNTQGLIFVVDSNDR[166.11]ER[166.11].L "sp|P18085|ARF4_HUMAN,sp|P84077|ARF1_HUMAN,sp|P61204|ARF3_HUMAN,sp|P84085|ARF5_HUMAN,tr|F5H423|F5H423_HUMAN,tr|C9J1Z8|C9J1Z8_HUMAN,tr|C9JPM4|C9JPM4_HUMAN,tr|C9JAK5|C9JAK5_HUMAN,tr|F5H0C7|F5H0C7_HUMAN" 9 2457.194 0.36 121516 19720 4 2457.202264 615.3058 ADP-ribosylation factor 4 OS=Homo sapiens OX=9606 GN=ARF4 PE=1 SV=3 5.38 3269.6 - 515430 - - - 3.3587 - 3.748 0.565 - 347 1 2 1 0.0083 20 0 0 0 5.02E+06 1.38E+07 - - - 4.5832 1 221125_WJC_METTL3_EV_vs_WT_F08.19721.19721.3 2.41E-10 19/92 K.DSGQWHYFDDNSVSPVNENQIESK[136.11].A "sp|P51784|UBP11_HUMAN,tr|G5E9A6|G5E9A6_HUMAN" 2 2802.2249 0.08 121517 19721 3 2803.232462 935.0822 Ubiquitin carboxyl-terminal hydrolase 11 OS=Homo sapiens OX=9606 GN=USP11 PE=1 SV=3 4.1 3269.7 - 338196 - - - 359.5646 - 4.017 0.718 - 397.5 1 2 0 1.0076 24 0 0 0 5.10E+05 6.06E+06 - - - 9.4955 0.9995 221125_WJC_METTL3_EV_vs_WT_F08.19722.19722.4 0.00031 16/222 R.ILKPAEGNPTDQAGFSEDRDFGYSVGLNPPEEEAVTSK.T sp|Q86XL3|ANKL2_HUMAN 1 4063.9287 2.36 121518 19722 4 4063.944569 1016.9895 Ankyrin repeat and LEM domain-containing protein 2 OS=Homo sapiens OX=9606 GN=ANKLE2 PE=1 SV=4 4.12 3269.8 - 192210 - - - 3.9048 - 2.834 0.556 - 70.9 1 2 1 0.0159 38 0 0 0 1.57E+07 6.65E+06 - - - 4.3648 0.999 221125_WJC_METTL3_EV_vs_WT_F08.19726.19726.3 3.77E-06 18/76 K.HYFQNTQGLIFVVDSNDRER.L "sp|P18085|ARF4_HUMAN,sp|P84077|ARF1_HUMAN,sp|P61204|ARF3_HUMAN,sp|P84085|ARF5_HUMAN,tr|F5H423|F5H423_HUMAN,tr|C9J1Z8|C9J1Z8_HUMAN,tr|C9JPM4|C9JPM4_HUMAN,tr|C9JAK5|C9JAK5_HUMAN,tr|F5H0C7|F5H0C7_HUMAN" 9 2437.1775 0.86 121520 19726 3 2437.188383 813.3998 ADP-ribosylation factor 4 OS=Homo sapiens OX=9606 GN=ARF4 PE=1 SV=3 5.38 3270.4 - 529648 - - - 4.4773 - 2.957 0.534 - 275 1 2 1 0.0109 20 0 0 0 1.10E+07 1.28E+07 - - - 7.1208 1 221125_WJC_METTL3_EV_vs_WT_F08.19727.19727.4 2.04E-11 26/204 R.SFAHLLPSPEPSPEGSYVGQHSQGLGGHYADSYLK.R "tr|K7EQG2|K7EQG2_HUMAN,tr|E9PAU2|E9PAU2_HUMAN,tr|A0A087WZ13|A0A087WZ13_HUMAN" 3 3711.7594 1.04 121521 19727 4 3711.763878 928.9471 Uncharacterized protein (Fragment) OS=Homo sapiens OX=9606 PE=1 SV=1 5.72 3270.5 - 315682 - - - 1.2091 - 4.3 0.682 - 231.3 1 2 0 0.0045 35 0 0 0 2.43E+08 2.34E+08 - - - 5.5933 1 221125_WJC_METTL3_EV_vs_WT_F08.19730.19730.4 4.09E-10 24/204 R.SFAHLLPSPEPSPEGSYVGQHSQGLGGHYADSYLK[136.11].R "tr|K7EQG2|K7EQG2_HUMAN,tr|E9PAU2|E9PAU2_HUMAN,tr|A0A087WZ13|A0A087WZ13_HUMAN" 3 3719.7736 1.04 121524 19730 4 3719.779687 930.9507 Uncharacterized protein (Fragment) OS=Homo sapiens OX=9606 PE=1 SV=1 5.72 3270.9 - 306948 - - - 1.6391 - 4.104 0.663 - 224.8 1 2 0 0.0061 35 0 0 0 2.43E+08 2.34E+08 - - - 5.4137 0.9997 221125_WJC_METTL3_EV_vs_WT_F08.19731.19731.4 1.08E-05 10/120 K.LK[136.11]ESSHSGVVLSVEEVEAGLK[136.11].G "sp|Q9NRA8|4ET_HUMAN,tr|B1AKL4|B1AKL4_HUMAN,tr|B0QYZ7|B0QYZ7_HUMAN" 3 2212.1922 0.92 121525 19731 4 2212.198039 554.0553 Eukaryotic translation initiation factor 4E transporter OS=Homo sapiens OX=9606 GN=EIF4ENIF1 PE=1 SV=2 4.91 3271 - 163272 - - - 2.6494 - 2.479 0.504 - 82.8 1 2 1 0.0059 21 0 0 0 2.82E+06 3.05E+06 - - - 3.9114 0.9994 221125_WJC_METTL3_EV_vs_WT_F08.19735.19735.4 2.55E-10 24/138 K.QREEYQPATPGLGMFVEVKDPEDK.V sp|Q9BVK6|TMED9_HUMAN 1 2762.3221 1.4 121527 19735 4 2762.334649 691.5878 Transmembrane emp24 domain-containing protein 9 OS=Homo sapiens OX=9606 GN=TMED9 PE=1 SV=2 4.36 3271.5 - 504578 - - - 4.5263 - 3.788 0.595 - 339 1 2 2 0.0125 24 0 0 0 8.45E+07 6.03E+07 - - - 4.8289 1 221125_WJC_METTL3_EV_vs_WT_F08.19737.19737.3 2.65E-07 Dec-92 K.ENALVQMADGNQAQLAMSHLNGHK[136.11].L "sp|P26599|PTBP1_HUMAN,tr|A0A0U1RRM4|A0A0U1RRM4_HUMAN,tr|A6NLN1|A6NLN1_HUMAN,tr|A0A0D9SF20|A0A0D9SF20_HUMAN,tr|A0A7I2V621|A0A7I2V621_HUMAN,tr|K7EK45|K7EK45_HUMAN" 6 2584.2366 0.86 121528 19737 3 2584.236371 862.4195 Polypyrimidine tract-binding protein 1 OS=Homo sapiens OX=9606 GN=PTBP1 PE=1 SV=1 6 3271.8 - 235696 - - - -0.0844 - 2.366 0.539 - 117.7 1 2 0 -0.0002 24 0 0 0 5.30E+06 6.20E+06 - - - 6.5495 0.9997 221125_WJC_METTL3_EV_vs_WT_F08.19750.19750.4 7.42E-10 30/138 K.QR[166.11]EEYQPATPGLGMFVEVK[136.11]DPEDK[136.11].V sp|Q9BVK6|TMED9_HUMAN 1 2788.3588 1.4 121537 19750 4 2788.368724 698.097 Transmembrane emp24 domain-containing protein 9 OS=Homo sapiens OX=9606 GN=TMED9 PE=1 SV=2 4.36 3273.4 - 1.15E+06 - - - 3.5533 - 4.641 0.586 - 576.8 1 2 2 0.0099 24 0 0 0 8.45E+07 6.03E+07 - - - 4.8165 0.9977 221125_WJC_METTL3_EV_vs_WT_F08.19764.19764.4 0.101 6/108 R.GLLQDDAHPTLVTYADHSK[136.11].L "sp|Q86U44|MTA70_HUMAN,tr|F5H6D8|F5H6D8_HUMAN,tr|H0YFV6|H0YFV6_HUMAN,tr|B4DTN4|B4DTN4_HUMAN" 4 2088.0367 0.001 121545 19764 4 2088.038529 523.0165 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 5.13 3275.3 - 62813.4 - - - 0.8601 - 1.536 0.27 - 31.2 1 2 0 0.0018 19 0 0 0 0.00E+00 3.27E+06 - - - 1.7208 0.9999 221125_WJC_METTL3_EV_vs_WT_F08.19770.19770.3 0.00013 16/56 R.STSHK[136.11]PDEIYGMIER[166.11].L sp|Q86U44|MTA70_HUMAN 1 1779.8581 0.11 121549 19770 3 1779.862381 594.2933 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 5.42 3276.1 - 287739 - - - 2.4311 - 2.723 0.473 - 309.7 1 2 0 0.0043 15 0 0 0 2.10E+06 1.93E+07 - - - 6.4262 0.9963 221125_WJC_METTL3_EV_vs_WT_F08.19773.19773.4 0.000497 11/132 K.DFDFESANAQFNKEEIDREFHNK.L "sp|Q8ND56|LS14A_HUMAN,tr|A0A140TA76|A0A140TA76_HUMAN,tr|K7EMZ9|K7EMZ9_HUMAN" 3 2829.2631 1.4 121550 19773 4 2829.268252 708.323 Protein LSM14 homolog A OS=Homo sapiens OX=9606 GN=LSM14A PE=1 SV=3 4.43 3276.5 - 552841 - - - 1.8383 - 1.829 0.324 - 27.5 1 2 2 0.0052 23 0 0 0 1.80E+07 1.29E+07 - - - 2.2403 1 221125_WJC_METTL3_EV_vs_WT_F08.19775.19775.4 1.59E-09 13/126 R.AYVESIC[160.03]SNNFDSFLHETHENK[136.11].Y "sp|Q7Z2W4|ZCCHV_HUMAN,tr|C9J6P4|C9J6P4_HUMAN,tr|A0A7P0T8C6|A0A7P0T8C6_HUMAN" 3 2648.1693 1.1 121552 19775 4 2648.177438 663.0496 Zinc finger CCCH-type antiviral protein 1 OS=Homo sapiens OX=9606 GN=ZC3HAV1 PE=1 SV=3 4.8 3276.8 - 300951 - - - 3.0802 - 2.872 0.633 - 70.4 1 2 0 0.0082 22 0 0 0 6.50E+06 5.91E+06 - - - 5.0786 0.9998 221125_WJC_METTL3_EV_vs_WT_F08.19794.19794.4 4.76E-09 17/144 K.K[136.11]LNC[160.03]QVIGASVDSHFC[160.03]HLAWVNTPK[136.11].K "sp|Q06830|PRDX1_HUMAN,tr|A0A0A0MSI0|A0A0A0MSI0_HUMAN" 2 2896.4447 0.66 121562 19794 4 2896.45846 725.1185 Peroxiredoxin-1 OS=Homo sapiens OX=9606 GN=PRDX1 PE=1 SV=1 8.06 3279.3 - 357256 - - - 4.7372 - 3.165 0.553 - 170.3 1 2 0 0.0137 25 0 0 0 1.32E+07 1.99E+07 - - - 4.402 1 221125_WJC_METTL3_EV_vs_WT_F08.19795.19795.3 2.99E-09 14/100 R.SNSSMAALIAQSENNQTDQDLGDNSR.N "sp|P55197|AF10_HUMAN,tr|Q5JT35|Q5JT35_HUMAN" 2 2765.2158 8.99 121563 19795 3 2765.203754 922.7459 Protein AF-10 OS=Homo sapiens OX=9606 GN=MLLT10 PE=1 SV=2 3.84 3279.4 - 287296 - - - -4.3718 - 3.054 0.664 - 195.3 1 2 0 -0.0121 26 0 0 0 2.43E+07 2.71E+06 - - - 8.5081 0.9993 221125_WJC_METTL3_EV_vs_WT_F08.19796.19796.4 0.000303 Jul-96 K.EHYVDLKDRPFFAGLVK.Y "sp|P15531|NDKA_HUMAN,tr|Q32Q12|Q32Q12_HUMAN,tr|J3KPD9|J3KPD9_HUMAN,tr|E5RHP0|E5RHP0_HUMAN,tr|E7ERL0|E7ERL0_HUMAN" 5 2033.0734 0.67 121564 19796 4 2033.075179 509.2756 Nucleoside diphosphate kinase A OS=Homo sapiens OX=9606 GN=NME1 PE=1 SV=1 6.85 3279.6 - 139887 - - - 0.8519 - 1.624 0.398 - 33.6 1 2 1 0.0017 17 0 0 0 3.76E+06 5.65E+06 - - - 2.8581 0.9928 221125_WJC_METTL3_EV_vs_WT_F08.19812.19812.4 0.000131 13/192 R.GIQLSPGVGSSAGPPGDLEDDEGLKHLQQEAEK.L sp|O75420|GGYF1_HUMAN 1 3357.6325 0.86 121572 19812 4 3357.6509 840.4154 GRB10-interacting GYF protein 1 OS=Homo sapiens OX=9606 GN=GIGYF1 PE=1 SV=2 4.19 3281.5 - 223680 - - - 5.4926 - 2.481 0.428 - 79.3 1 2 1 0.0184 33 0 0 0 9.72E+06 1.13E+07 - - - 3.2188 1 221125_WJC_METTL3_EV_vs_WT_F08.19816.19816.3 6.79E-06 Sep-52 K.K[136.11]GPGEVAGTVTGQK[136.11].R "sp|Q86U44|MTA70_HUMAN,tr|F5H6D8|F5H6D8_HUMAN,tr|H0YFV6|H0YFV6_HUMAN,tr|B4DTN4|B4DTN4_HUMAN" 4 1343.738 0 121574 19816 3 1343.738724 448.9199 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 8.59 3282.1 - 171527 - - - 0.5544 - 2.154 0.506 - 156.3 1 2 0 0.0007 14 0 0 0 5.22E+04 1.14E+07 - - - 6.2204 0.998 221125_WJC_METTL3_EV_vs_WT_F08.19828.19828.3 0.015 6/116 M.PGPTQTLSPNGENNNDIIQDNNGTIIPFRK.H sp|Q15555|MARE2_HUMAN 1 3263.6171 64.75 121579 19828 3 3263.615544 1088.8796 Microtubule-associated protein RP\EB family member 2 OS=Homo sapiens OX=9606 GN=MAPRE2 PE=1 SV=1 4.56 3283.7 - 229924 - - - -0.4716 - 1.434 0.309 - 16.8 1 2 0 -0.0015 30 0 0 0 1.61E+07 2.48E+05 - - - 2.8139 1 221125_WJC_METTL3_EV_vs_WT_F08.19832.19832.4 3.03E-09 25/180 R.KIYC[160.03]VAC[160.03]QELDSDVDKDNPALNAQAALSQAR.E "sp|O60232|ZNRD2_HUMAN,tr|H0YEB6|H0YEB6_HUMAN,tr|G3V1B8|G3V1B8_HUMAN" 3 3462.6508 2.15 121580 19832 4 3462.648309 866.67 Protein ZNRD2 OS=Homo sapiens OX=9606 GN=ZNRD2 PE=1 SV=1 4.36 3284.3 - 797467 - - - -0.7101 - 4.722 0.726 - 401.5 1 2 1 -0.0025 31 0 0 0 4.66E+07 2.17E+07 - - - 6.0162 0.9999 221125_WJC_METTL3_EV_vs_WT_F08.19839.19839.4 0.0778 13/108 R.TSQNSELNNMQDLVEDYKK.K sp|P35908|K22E_HUMAN 1 2255.0376 5.83 121584 19839 4 2255.037725 564.7667 "Keratin, type II cytoskeletal 2 epidermal OS=Homo sapiens OX=9606 GN=KRT2 PE=1 SV=2" 4.32 3285.1 - 1.09E+06 - - - 0.0594 - 2.441 0.405 - 99.7 1 2 0 0.0001 19 0 0 0 2.89E+08 4.95E+07 - - - 3.053 1 221125_WJC_METTL3_EV_vs_WT_F08.19842.19842.3 2.19E-08 23/116 K.DSAHLMNGPISQTTSQTSSIPPLSQVPATK.V "sp|Q92615|LAR4B_HUMAN,tr|B5MCU2|B5MCU2_HUMAN,tr|X6RCG6|X6RCG6_HUMAN" 3 3092.5448 1.38 121586 19842 3 3092.54182 1031.8556 La-related protein 4B OS=Homo sapiens OX=9606 GN=LARP4B PE=1 SV=3 6.74 3285.5 - 952335 - - - -0.973 - 4.241 0.704 - 214.3 1 2 0 -0.003 30 0 0 0 3.32E+08 2.41E+08 - - - 9.712 1 221125_WJC_METTL3_EV_vs_WT_F08.19843.19843.4 1.31E-09 20/144 K.KLNC[160.03]QVIGASVDSHFC[160.03]HLAWVNTPK.K "sp|Q06830|PRDX1_HUMAN,tr|A0A0A0MSI0|A0A0A0MSI0_HUMAN" 2 2880.4163 0.65 121587 19843 4 2880.420345 721.1114 Peroxiredoxin-1 OS=Homo sapiens OX=9606 GN=PRDX1 PE=1 SV=1 8.06 3285.6 - 478622 - - - 1.3908 - 3.91 0.62 - 256.8 1 2 0 0.004 25 0 0 0 1.30E+07 2.00E+07 - - - 5.0551 1 221125_WJC_METTL3_EV_vs_WT_F08.19848.19848.4 1.15E-10 27/180 R.K[136.11]IYC[160.03]VAC[160.03]QELDSDVDK[136.11]DNPALNAQAALSQAR[166.11].E "sp|O60232|ZNRD2_HUMAN,tr|H0YEB6|H0YEB6_HUMAN,tr|G3V1B8|G3V1B8_HUMAN" 3 3488.6874 2.02 121590 19848 4 3488.685095 873.1791 Protein ZNRD2 OS=Homo sapiens OX=9606 GN=ZNRD2 PE=1 SV=1 4.36 3286.3 - 863616 - - - -0.6716 - 4.47 0.679 - 422.2 1 2 1 -0.0023 31 0 0 0 4.38E+07 2.17E+07 - - - 5.5905 1 221125_WJC_METTL3_EV_vs_WT_F08.19850.19850.2 2.10E-08 13/36 R.TSQNSELNNMQDLVEDYKK.K sp|P35908|K22E_HUMAN 1 2255.0376 999 121591 19850 2 2255.031466 1128.5261 "Keratin, type II cytoskeletal 2 epidermal OS=Homo sapiens OX=9606 GN=KRT2 PE=1 SV=2" 4.32 3286.5 - 611486 - - - -2.7161 - 3.415 0.636 - 458.6 1 2 0 -0.0061 19 0 0 0 1.03E+08 0.00E+00 - - - 6.7561 1 221125_WJC_METTL3_EV_vs_WT_F08.19859.19859.3 5.82E-11 16/116 K.DSAHLMNGPISQTTSQTSSIPPLSQVPATK[136.11].V "sp|Q92615|LAR4B_HUMAN,tr|B5MCU2|B5MCU2_HUMAN,tr|X6RCG6|X6RCG6_HUMAN" 3 3100.559 1.38 121595 19859 3 3100.551129 1034.527 La-related protein 4B OS=Homo sapiens OX=9606 GN=LARP4B PE=1 SV=3 6.74 3287.6 - 548459 - - - -2.5479 - 3.064 0.684 - 102.9 1 2 0 -0.0079 30 0 0 0 3.31E+08 2.40E+08 - - - 8.7398 0.9956 221125_WJC_METTL3_EV_vs_WT_F08.19868.19868.4 0.0577 15/126 K.QAVDFLSNEGHIYSTVDDDHFK.S "sp|P15927|RFA2_HUMAN,tr|Q5TEJ0|Q5TEJ0_HUMAN" 2 2536.1506 8.94 121600 19868 4 2536.151763 635.0449 Replication protein A 32 kDa subunit OS=Homo sapiens OX=9606 GN=RPA2 PE=1 SV=1 4.34 3288.9 - 877600 - - - 0.44 - 2.448 0.224 - 114.3 1 2 0 0.0011 22 0 0 0 2.58E+07 2.89E+06 - - - 1.4683 0.9999 221125_WJC_METTL3_EV_vs_WT_F08.19881.19881.4 3.73E-07 16/138 K.KVTSVVFHPSQDLVFSASPDATIR.L sp|Q9UMS4|PRP19_HUMAN 1 2600.3599 2.01 121607 19881 4 2600.366507 651.0972 Pre-mRNA-processing factor 19 OS=Homo sapiens OX=9606 GN=PRPF19 PE=1 SV=1 6.75 3290.5 - 569812 - - - 2.5593 - 3.215 0.492 - 176.8 1 2 0 0.0067 24 0 0 0 1.26E+07 6.29E+06 - - - 3.8814 1 221125_WJC_METTL3_EV_vs_WT_F08.19890.19890.3 3.59E-11 23/72 R.TSQNSELNNMQDLVEDYKK.K sp|P35908|K22E_HUMAN 1 2255.0376 999 121611 19890 3 2255.033262 752.6865 "Keratin, type II cytoskeletal 2 epidermal OS=Homo sapiens OX=9606 GN=KRT2 PE=1 SV=2" 4.32 3291.5 - 2.90E+08 - - - -1.9197 - 4.159 0.657 - 668 1 2 0 -0.0043 19 0 0 0 1.05E+10 0.00E+00 - - - 9.3653 1 221125_WJC_METTL3_EV_vs_WT_F08.19894.19894.3 2.00E-12 19/68 K.DFDFESANAQFNKEEIDR.E "sp|Q8ND56|LS14A_HUMAN,tr|A0A140TA76|A0A140TA76_HUMAN,tr|K7EMZ9|K7EMZ9_HUMAN" 3 2173.9552 0.94 121612 19894 3 2173.944872 725.659 Protein LSM14 homolog A OS=Homo sapiens OX=9606 GN=LSM14A PE=1 SV=3 4.02 3292.1 - 1.03E+06 - - - -4.7701 - 3.65 0.737 - 316 1 2 1 -0.0104 18 0 0 0 3.16E+07 3.35E+07 - - - 9.978 1 221125_WJC_METTL3_EV_vs_WT_F08.19896.19896.3 4.44E-11 19/68 K.DFDFESANAQFNK[136.11]EEIDR[166.11].E "sp|Q8ND56|LS14A_HUMAN,tr|A0A140TA76|A0A140TA76_HUMAN,tr|K7EMZ9|K7EMZ9_HUMAN" 3 2191.9777 0.94 121613 19896 3 2191.974913 731.6665 Protein LSM14 homolog A OS=Homo sapiens OX=9606 GN=LSM14A PE=1 SV=3 4.02 3292.3 - 940306 - - - -1.2769 - 3.532 0.695 - 267.4 1 2 1 -0.0028 18 0 0 0 3.16E+07 3.35E+07 - - - 9.43 1 221125_WJC_METTL3_EV_vs_WT_F08.19917.19917.3 8.64E-19 31/124 K.VGGTKPAGGDFGEVLNSAANASATTTEPLPEK.T "sp|P55327|TPD52_HUMAN,tr|E5RK35|E5RK35_HUMAN" 2 3085.5204 1.15 121621 19917 3 3085.516474 1029.5141 Tumor protein D52 OS=Homo sapiens OX=9606 GN=TPD52 PE=1 SV=2 4.41 3295 - 1.24E+06 - - - -1.2685 - 5.851 0.655 - 604.5 1 2 0 -0.0039 32 0 0 0 1.01E+08 8.73E+07 - - - 9.9059 0.9878 221125_WJC_METTL3_EV_vs_WT_F08.19918.19918.2 0.0378 14-Jun R.VDEIIWVK[136.11].T sp|Q86U44|MTA70_HUMAN 1 1008.5735 0.01 121622 19918 2 1008.569458 505.294 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 4.37 3295.1 - 387955 - - - -4.0404 - 1.723 0.199 - 111.7 1 2 0 -0.0041 8 0 0 0 1.27E+06 1.84E+08 - - - 2.1504 0.9999 221125_WJC_METTL3_EV_vs_WT_F08.19920.19920.3 5.82E-05 14/64 K.K[136.11]IGDEYFTFITDC[160.03]K[136.11]DPK[136.11].A "sp|P49368|TCPG_HUMAN,tr|B4DUR8|B4DUR8_HUMAN" 2 2100.03 0.43 121624 19920 3 2100.029506 701.0173 T-complex protein 1 subunit gamma OS=Homo sapiens OX=9606 GN=CCT3 PE=1 SV=4 4.68 3295.4 - 331213 - - - -0.2324 - 2.699 0.499 - 170.4 1 2 1 -0.0005 17 0 0 0 4.24E+06 9.94E+06 - - - 6.6115 0.998 221125_WJC_METTL3_EV_vs_WT_F08.19921.19921.4 0.000202 Oct-96 K.K[136.11]IGDEYFTFITDC[160.03]K[136.11]DPK[136.11].A "sp|P49368|TCPG_HUMAN,tr|B4DUR8|B4DUR8_HUMAN" 2 2100.03 1.06 121625 19921 4 2100.02303 526.0148 T-complex protein 1 subunit gamma OS=Homo sapiens OX=9606 GN=CCT3 PE=1 SV=4 4.68 3295.5 - 276369 - - - -3.3161 - 1.804 0.416 - 66.1 1 2 1 -0.007 17 0 0 0 1.09E+07 1.03E+07 - - - 3.0498 0.8468 221125_WJC_METTL3_EV_vs_WT_F08.19926.19926.3 0.000101 15/72 K.SKELTTEIDNNIEQISSYK.S "sp|P13645|K1C10_HUMAN,tr|A0A1B0GVI3|A0A1B0GVI3_HUMAN" 2 2211.0907 999 121628 19926 3 2212.085108 738.0375 "Keratin, type I cytoskeletal 10 OS=Homo sapiens OX=9606 GN=KRT10 PE=1 SV=6" 4.41 3296.2 - 722665 - - - 449.7486 - 2.735 0.356 - 233.7 1 2 1 0.9944 19 0 0 0 1.67E+09 0.00E+00 - - - 4.7055 0.9952 221125_WJC_METTL3_EV_vs_WT_F08.19930.19930.4 0.216 Aug-84 R.STSHK[136.11]PDEIYGMIER[166.11].L sp|Q86U44|MTA70_HUMAN 1 1779.8581 0.001 121632 19930 4 1779.857895 445.9718 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 5.42 3296.7 - 303739 - - - -0.0893 - 1.267 0.244 - 36.9 1 2 0 -0.0002 15 0 0 0 0.00E+00 7.73E+06 - - - 1.4344 1 221125_WJC_METTL3_EV_vs_WT_F08.19935.19935.4 3.03E-09 27/186 K.VGGTKPAGGDFGEVLNSAANASATTTEPLPEK.T "sp|P55327|TPD52_HUMAN,tr|E5RK35|E5RK35_HUMAN" 2 3085.5204 1.36 121635 19935 4 3085.524734 772.3874 Tumor protein D52 OS=Homo sapiens OX=9606 GN=TPD52 PE=1 SV=2 4.41 3297.3 - 947066 - - - 1.4085 - 5.004 0.64 - 265.8 1 2 0 0.0043 32 0 0 0 2.17E+07 1.60E+07 - - - 5.2815 0.9999 221125_WJC_METTL3_EV_vs_WT_F08.19936.19936.4 0.000701 10/186 K.VGGTK[136.11]PAGGDFGEVLNSAANASATTTEPLPEK[136.11].T "sp|P55327|TPD52_HUMAN,tr|E5RK35|E5RK35_HUMAN" 2 3101.5488 1.38 121636 19936 4 3101.550908 776.3945 Tumor protein D52 OS=Homo sapiens OX=9606 GN=TPD52 PE=1 SV=2 4.41 3297.5 - 767626 - - - 0.6835 - 2.487 0.464 - 32 1 2 0 0.0021 32 0 0 0 2.17E+07 1.57E+07 - - - 3.5392 0.9997 221125_WJC_METTL3_EV_vs_WT_F08.19943.19943.3 3.74E-05 Aug-64 K.KIGDEYFTFITDC[160.03]KDPK.A "sp|P49368|TCPG_HUMAN,tr|B4DUR8|B4DUR8_HUMAN" 2 2075.9874 0.45 121641 19943 3 2075.990077 693.0031 T-complex protein 1 subunit gamma OS=Homo sapiens OX=9606 GN=CCT3 PE=1 SV=4 4.68 3298.4 - 131528 - - - 1.2924 - 2.084 0.483 - 55.6 1 2 1 0.0027 17 0 0 0 4.47E+06 1.00E+07 - - - 5.7793 1 221125_WJC_METTL3_EV_vs_WT_F08.19947.19947.3 1.27E-12 18/124 R.TSSDSALHTSVMNPSPQDTYPGPTPPSILPSR.R "sp|Q53ET0|CRTC2_HUMAN,tr|H0YDQ8|H0YDQ8_HUMAN" 2 3336.5932 1.19 121643 19947 3 3336.599088 1113.205 CREB-regulated transcription coactivator 2 OS=Homo sapiens OX=9606 GN=CRTC2 PE=1 SV=2 5.18 3299 - 355445 - - - 1.7539 - 3.379 0.73 - 137.7 1 2 0 0.0059 32 0 0 0 7.39E+06 6.23E+06 - - - 9.4784 0.9861 221125_WJC_METTL3_EV_vs_WT_F08.19960.19960.2 2.39E-07 20-Oct F.LNTC[160.03]FHMDTC[160.03]K[136.11].Y "sp|Q86U44|MTA70_HUMAN,tr|H0YFV6|H0YFV6_HUMAN" 2 1433.5981 0.001 121650 19960 2 1433.595026 717.8063 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 6.73 3300.5 - 316478 - - - -2.1631 - 2.664 0.488 - 527 1 1 0 -0.0031 11 0 0 0 0.00E+00 1.95E+07 - - - 5.2951 1 221125_WJC_METTL3_EV_vs_WT_F08.19964.19964.2 3.37E-16 20/42 K.HTDESLGDC[160.03]SFLNTC[160.03]FHMDTC[160.03]K[136.11].Y "sp|Q86U44|MTA70_HUMAN,tr|H0YFV6|H0YFV6_HUMAN" 2 2682.0698 0.001 121652 19964 2 2682.065396 1342.0422 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 4.64 3301 - 293805 - - - -1.6584 - 4.512 0.841 - 880 1 2 0 -0.0044 22 0 0 0 0.00E+00 1.43E+07 - - - 8.9556 1 221125_WJC_METTL3_EV_vs_WT_F08.19974.19974.3 7.05E-07 13/128 R.SDSPVPTAPTSGGPK[136.11]PSTASAVPELATDPELEK[136.11].K "sp|Q86U44|MTA70_HUMAN,tr|B4E349|B4E349_HUMAN,tr|F5H6D8|F5H6D8_HUMAN,tr|B4DTN4|B4DTN4_HUMAN" 4 3248.6271 0.01 121657 19974 3 3248.622764 1083.883 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 4.18 3302.2 - 791811 - - - -1.3341 - 2.757 0.556 - 77.2 1 2 0 -0.0043 33 0 0 0 3.59E+05 4.14E+07 - - - 7.0708 1 221125_WJC_METTL3_EV_vs_WT_F08.19992.19992.2 2.98E-06 13/24 C.SFLNTC[160.03]FHMDTC[160.03]K[136.11].Y "sp|Q86U44|MTA70_HUMAN,tr|H0YFV6|H0YFV6_HUMAN" 2 1667.6986 0.001 121663 19992 2 1667.690496 834.8566 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 6.45 3304.6 - 344937 - - - -4.8408 - 2.852 0.674 - 411.1 1 1 0 -0.0081 13 0 0 0 0.00E+00 1.55E+07 - - - 6.7064 1 221125_WJC_METTL3_EV_vs_WT_F08.19995.19995.4 2.24E-10 19/156 K.FC[160.03]KYEHDDIVSTVSVLSSGTQAVSGSK.D "sp|Q9BQA1|MEP50_HUMAN,tr|H0Y711|H0Y711_HUMAN" 2 2900.3862 0.78 121665 19995 4 2900.378053 726.1038 Methylosome protein 50 OS=Homo sapiens OX=9606 GN=WDR77 PE=1 SV=1 5.38 3305 - 915147 - - - -2.81 - 4.022 0.661 - 247.3 1 2 1 -0.0081 27 0 0 0 2.57E+07 3.28E+07 - - - 5.4126 1 221125_WJC_METTL3_EV_vs_WT_F08.20010.20010.2 5.00E-07 22-Dec S.FLNTC[160.03]FHMDTC[160.03]K[136.11].Y "sp|Q86U44|MTA70_HUMAN,tr|H0YFV6|H0YFV6_HUMAN" 2 1580.6665 0.001 121672 20010 2 1580.66106 791.3405 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 6.73 3306.8 - 209692 - - - -3.4675 - 2.645 0.643 - 384.9 1 1 0 -0.0055 12 0 0 0 0.00E+00 9.84E+06 - - - 6.3477 1 221125_WJC_METTL3_EV_vs_WT_F08.20013.20013.3 8.01E-08 18/72 K.HSSDASSLLPQNILSQTSR.H "sp|Q9BTA9|WAC_HUMAN,tr|A0A7P0T961|A0A7P0T961_HUMAN,tr|J3QTA0|J3QTA0_HUMAN" 3 2040.0236 1.75 121673 20013 3 2040.020258 681.0151 WW domain-containing adapter protein with coiled-coil OS=Homo sapiens OX=9606 GN=WAC PE=1 SV=3 6.74 3307.2 - 1.59E+06 - - - -1.6363 - 3.229 0.587 - 477.5 1 2 0 -0.0033 19 0 0 0 6.40E+07 3.66E+07 - - - 7.9633 0.9999 221125_WJC_METTL3_EV_vs_WT_F08.20031.20031.4 3.90E-07 14/114 K.C[160.03]R[166.11]APEVSQHVYQAYETILK[136.11]N.- sp|Q10567|AP1B1_HUMAN 1 2423.2022 0.45 121682 20031 4 2423.207798 606.8078 AP-1 complex subunit beta-1 OS=Homo sapiens OX=9606 GN=AP1B1 PE=1 SV=2 6.75 3309.6 - 176358 - - - 2.2899 - 2.762 0.568 - 150 1 2 1 0.0055 20 0 0 0 9.24E+06 2.04E+07 - - - 4.508 0.9931 221125_WJC_METTL3_EV_vs_WT_F08.20032.20032.4 0.0326 14/120 R.KKESDLPSAILQTSGVSEFTK.K sp|Q99459|CDC5L_HUMAN 1 2264.19 2.51 121683 20032 4 2264.186886 567.0548 Cell division cycle 5-like protein OS=Homo sapiens OX=9606 GN=CDC5L PE=1 SV=2 6.18 3309.8 - 488499 - - - -1.3722 - 2.214 0.268 - 85.4 1 2 1 -0.0031 21 0 0 0 4.48E+07 1.78E+07 - - - 1.8206 0.9999 221125_WJC_METTL3_EV_vs_WT_F08.20034.20034.4 3.76E-08 19/186 R.AGGDAEPRPAEPPAWAGGARPGPGVWDPNWDR.R sp|Q96HS1|PGAM5_HUMAN 1 3308.55 1.85 121685 20034 4 3308.560841 828.1448 "Serine\threonine-protein phosphatase PGAM5, mitochondrial OS=Homo sapiens OX=9606 GN=PGAM5 PE=1 SV=2" 4.44 3310 - 434290 - - - 3.2748 - 2.491 0.578 - 129.9 1 2 0 0.0108 32 0 0 0 1.25E+07 6.78E+06 - - - 4.5295 1 221125_WJC_METTL3_EV_vs_WT_F08.20039.20039.4 1.25E-08 24/150 K.K[136.11]QPTGTVPLSVTAALQLTHSQEDSSR[166.11].C "sp|Q8IXK0|PHC2_HUMAN,tr|A0A0A0MSI2|A0A0A0MSI2_HUMAN,tr|B3KPJ4|B3KPJ4_HUMAN" 3 2768.4424 1.48 121688 20039 4 2768.444221 693.1179 Polyhomeotic-like protein 2 OS=Homo sapiens OX=9606 GN=PHC2 PE=1 SV=1 6.75 3310.6 - 695783 - - - 0.6737 - 4.344 0.628 - 370.1 1 2 0 0.0019 26 0 0 0 2.33E+07 1.57E+07 - - - 5.1549 1 221125_WJC_METTL3_EV_vs_WT_F08.20040.20040.4 1.39E-09 14/90 K.R[166.11]GIEK[136.11]PPFELPDFIK[136.11]R[166.11].T "sp|Q13435|SF3B2_HUMAN,tr|E9PPJ0|E9PPJ0_HUMAN" 2 1977.1286 0.27 121689 20040 4 1977.129424 495.2894 Splicing factor 3B subunit 2 OS=Homo sapiens OX=9606 GN=SF3B2 PE=1 SV=2 8.59 3310.7 - 140475 - - - 0.438 - 2.959 0.624 - 186.4 1 2 0 0.0009 16 0 0 0 4.11E+06 1.52E+07 - - - 5.0392 1 221125_WJC_METTL3_EV_vs_WT_F08.20043.20043.4 1.22E-12 28/150 K.KQPTGTVPLSVTAALQLTHSQEDSSR.C "sp|Q8IXK0|PHC2_HUMAN,tr|A0A0A0MSI2|A0A0A0MSI2_HUMAN,tr|B3KPJ4|B3KPJ4_HUMAN" 3 2750.4199 1.49 121690 20043 4 2750.426201 688.6122 Polyhomeotic-like protein 2 OS=Homo sapiens OX=9606 GN=PHC2 PE=1 SV=1 6.75 3311.1 - 989481 - - - 2.296 - 5.122 0.68 - 556.8 1 2 0 0.0063 26 0 0 0 2.34E+07 1.57E+07 - - - 5.6582 0.9998 221125_WJC_METTL3_EV_vs_WT_F08.20044.20044.3 0.000148 14/80 R.KKESDLPSAILQTSGVSEFTK.K sp|Q99459|CDC5L_HUMAN 1 2264.19 2.26 121691 20044 3 2264.187864 755.7373 Cell division cycle 5-like protein OS=Homo sapiens OX=9606 GN=CDC5L PE=1 SV=2 6.18 3311.2 - 706090 - - - -0.9403 - 2.752 0.435 - 205.7 1 2 1 -0.0021 21 0 0 0 3.06E+07 1.35E+07 - - - 5.8162 0.9996 221125_WJC_METTL3_EV_vs_WT_F08.20045.20045.4 2.63E-05 20/120 R.K[136.11]K[136.11]ESDLPSAILQTSGVSEFTK[136.11].K sp|Q99459|CDC5L_HUMAN 1 2288.2326 2.54 121692 20045 4 2288.239303 573.0654 Cell division cycle 5-like protein OS=Homo sapiens OX=9606 GN=CDC5L PE=1 SV=2 6.18 3311.4 - 530461 - - - 2.9324 - 3.604 0.501 - 384.7 1 2 1 0.0067 21 0 0 0 4.50E+07 1.77E+07 - - - 4.0087 1 221125_WJC_METTL3_EV_vs_WT_F08.20050.20050.4 2.83E-10 24/150 R.GHGDSVDQLC[160.03]WHPSNPDLFVTASGDK.T sp|Q96J01|THOC3_HUMAN 1 2838.2668 0.63 121695 20050 4 2838.270799 710.574 THO complex subunit 3 OS=Homo sapiens OX=9606 GN=THOC3 PE=1 SV=1 4.54 3312 - 987108 - - - 1.4241 - 4.11 0.666 - 317.6 1 2 0 0.004 26 0 0 0 1.99E+07 3.17E+07 - - - 5.4676 1 221125_WJC_METTL3_EV_vs_WT_F08.20051.20051.4 3.91E-15 25/162 R.GHSSFVNEATFTQDGHYIISASSDGTVK.L sp|Q2TAY7|SMU1_HUMAN 1 2954.3682 0.91 121696 20051 4 2954.370795 739.5993 WD40 repeat-containing protein SMU1 OS=Homo sapiens OX=9606 GN=SMU1 PE=1 SV=2 5.21 3312.2 - 745887 - - - 0.8631 - 4.195 0.682 - 396.2 1 2 0 0.0026 28 0 0 0 1.13E+07 1.24E+07 - - - 5.6066 0.9999 221125_WJC_METTL3_EV_vs_WT_F08.20054.20054.3 9.98E-06 Aug-52 K.K[136.11]GPGEVAGTVTGQK[136.11].R "sp|Q86U44|MTA70_HUMAN,tr|F5H6D8|F5H6D8_HUMAN,tr|H0YFV6|H0YFV6_HUMAN,tr|B4DTN4|B4DTN4_HUMAN" 4 1343.738 0.001 121698 20054 3 1343.735524 448.9199 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 8.59 3312.5 - 180759 - - - -1.827 - 1.949 0.518 - 110.9 1 2 0 -0.0025 14 0 0 0 0.00E+00 9.50E+06 - - - 6.0879 0.9999 221125_WJC_METTL3_EV_vs_WT_F08.20056.20056.3 1.14E-07 20/80 R.K[136.11]K[136.11]ESDLPSAILQTSGVSEFTK[136.11].K sp|Q99459|CDC5L_HUMAN 1 2288.2326 2.23 121699 20056 3 2288.233025 763.7515 Cell division cycle 5-like protein OS=Homo sapiens OX=9606 GN=CDC5L PE=1 SV=2 6.18 3312.7 - 510795 - - - 0.1888 - 3.578 0.511 - 567.9 1 2 1 0.0004 21 0 0 0 3.01E+07 1.35E+07 - - - 7.2933 0.9999 221125_WJC_METTL3_EV_vs_WT_F08.20058.20058.4 4.97E-06 14/132 R.C[160.03]KDLNTFLHEPFSSVAATC[160.03]QTPK.L sp|Q9H1E1|RNAS7_HUMAN 1 2650.252 114.18 121701 20058 4 2650.254899 663.5703 Ribonuclease 7 OS=Homo sapiens OX=9606 GN=RNASE7 PE=1 SV=2 6.73 3313 - 172715 - - - 1.1093 - 2.952 0.5 - 146.6 1 2 1 0.0029 23 0 0 0 1.02E+07 8.90E+04 - - - 3.9279 1 221125_WJC_METTL3_EV_vs_WT_F08.20065.20065.3 1.06E-09 13/100 R.GHGDSVDQLC[160.03]WHPSNPDLFVTASGDK.T sp|Q96J01|THOC3_HUMAN 1 2838.2668 0.84 121705 20065 3 2838.266025 947.0962 THO complex subunit 3 OS=Homo sapiens OX=9606 GN=THOC3 PE=1 SV=1 4.54 3314 - 192560 - - - -0.2579 - 2.842 0.745 - 136.7 1 2 0 -0.0007 26 0 0 0 2.26E+06 2.69E+06 - - - 9.2488 1 221125_WJC_METTL3_EV_vs_WT_F08.20070.20070.4 3.69E-07 13/102 R.SPSELFAQHIVTIVHHVK.E "sp|Q9Y2W1|TR150_HUMAN,tr|A0A3B3ITZ9|A0A3B3ITZ9_HUMAN" 2 2041.1109 2.63 121707 20070 4 2041.114037 511.285 Thyroid hormone receptor-associated protein 3 OS=Homo sapiens OX=9606 GN=THRAP3 PE=1 SV=2 6.78 3314.7 - 289405 - - - 1.5394 - 2.844 0.551 - 116.6 1 2 0 0.0031 18 0 0 0 7.62E+08 2.90E+08 - - - 4.3791 1 221125_WJC_METTL3_EV_vs_WT_F08.20072.20072.3 3.08E-09 14/92 R.ATC[160.03]NNYTPQFQLRPSYSSC[160.03]FPQYR.S sp|Q5T749|KPRP_HUMAN 1 2984.3334 999 121709 20072 3 2984.337615 995.7851 Keratinocyte proline-rich protein OS=Homo sapiens OX=9606 GN=KPRP PE=1 SV=1 8.86 3315 - 280912 - - - 1.4134 - 2.74 0.615 - 118.8 1 2 0 0.0042 24 0 0 0 6.49E+06 0.00E+00 - - - 7.7366 1 221125_WJC_METTL3_EV_vs_WT_F08.20075.20075.3 1.63E-15 29/84 K.HTDESLGDC[160.03]SFLNTC[160.03]FHMDTC[160.03]K[136.11].Y "sp|Q86U44|MTA70_HUMAN,tr|H0YFV6|H0YFV6_HUMAN" 2 2682.0698 0.02 121710 20075 3 2683.071154 895.0306 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 4.64 3315.4 - 1.49E+06 - - - 373.3348 - 5.304 0.761 - 1298.6 1 2 0 1.0013 22 0 0 0 4.67E+07 2.37E+09 - - - 10.7027 0.9657 221125_WJC_METTL3_EV_vs_WT_F08.20079.20079.3 0.0221 9/116 K.DSAHLMNGPISQTTSQTSSIPPLSQVPATK.V "sp|Q92615|LAR4B_HUMAN,tr|B5MCU2|B5MCU2_HUMAN,tr|X6RCG6|X6RCG6_HUMAN" 3 3092.5448 4.04 121713 20079 3 3093.537821 1031.8556 La-related protein 4B OS=Homo sapiens OX=9606 GN=LARP4B PE=1 SV=3 6.74 3315.9 - 415699 - - - 321.0922 - 1.8 0.426 - 28.1 1 2 0 0.993 30 0 0 0 5.33E+06 1.32E+06 - - - 4.3667 0.9969 221125_WJC_METTL3_EV_vs_WT_F08.20091.20091.3 1.81E-05 15/124 R.AAASSYNTQGAASSLGSYGAQAASYGAQSAAS.S sp|Q96PK6|RBM14_HUMAN 1 2925.3013 - 121722 20091 3 2925.304977 976.1077 RNA-binding protein 14 OS=Homo sapiens OX=9606 GN=RBM14 PE=1 SV=2 5.57 3317.4 - 346086 - - - 1.2614 - 3.18 0.507 - 143.2 1 1 0 0.0037 32 0 0 0 - - - - - 6.8531 0.9996 221125_WJC_METTL3_EV_vs_WT_F08.20092.20092.3 2.10E-05 14/52 K.ILLAELEQLKGQGK.S "sp|P08670|VIME_HUMAN,tr|B0YJC4|B0YJC4_HUMAN,tr|A0A1B0GTT5|A0A1B0GTT5_HUMAN" 3 1538.9032 1.53 121723 20092 3 1538.903735 513.975 Vimentin OS=Homo sapiens OX=9606 GN=VIM PE=1 SV=4 6.14 3317.5 - 229820 - - - 0.3522 - 2.546 0.376 - 273.6 1 2 1 0.0005 14 0 0 0 3.80E+06 2.48E+06 - - - 5.2154 0.9997 221125_WJC_METTL3_EV_vs_WT_F08.20093.20093.3 7.94E-05 Nov-80 K.WQHDLFDSGFGGGAGVETGGK.L "sp|Q86V81|THOC4_HUMAN,tr|E9PB61|E9PB61_HUMAN" 2 2120.9552 0.72 121724 20093 3 2120.955289 707.9923 THO complex subunit 4 OS=Homo sapiens OX=9606 GN=ALYREF PE=1 SV=3 4.54 3317.7 - 162980 - - - 0.0504 - 1.788 0.392 - 95.9 1 2 0 0.0001 21 0 0 0 2.73E+06 3.76E+06 - - - 4.3035 1 221125_WJC_METTL3_EV_vs_WT_F08.20097.20097.4 3.56E-13 18/132 R.DYEVSDSAPHLEGLAEFQENVRK.T sp|Q9HBM1|SPC25_HUMAN 1 2632.2405 0.45 121726 20097 4 2632.245204 659.0674 Kinetochore protein Spc25 OS=Homo sapiens OX=9606 GN=SPC25 PE=1 SV=1 4.35 3318.2 - 383213 - - - 1.7776 - 3.17 0.603 - 94 1 2 0 0.0047 23 0 0 0 4.84E+06 1.06E+07 - - - 4.847 1 221125_WJC_METTL3_EV_vs_WT_F08.20102.20102.3 2.88E-08 11/104 R.ENENGEEEEEEAEFGEEDLFHQQGDPR.T sp|Q03252|LMNB2_HUMAN 1 3191.2712 1.88 121731 20102 3 3191.276971 1064.7643 Lamin-B2 OS=Homo sapiens OX=9606 GN=LMNB2 PE=1 SV=4 3.73 3318.9 - 253512 - - - 1.8181 - 2.115 0.751 - 39.2 1 2 0 0.0058 27 0 0 0 2.87E+06 1.53E+06 - - - 8.6346 0.9985 221125_WJC_METTL3_EV_vs_WT_F08.20111.20111.2 0.0491 14-Jun R.ILELDQFK[136.11].G "sp|P12956|XRCC6_HUMAN,tr|B1AHC9|B1AHC9_HUMAN" 2 1012.5684 0.39 121738 20111 2 1012.57056 507.2915 X-ray repair cross-complementing protein 6 OS=Homo sapiens OX=9606 GN=XRCC6 PE=1 SV=2 4.37 3320 - 114034 - - - 2.0868 - 1.453 0.361 - 60 1 2 0 0.0021 8 0 0 0 1.74E+06 4.50E+06 - - - 2.8335 0.9793 221125_WJC_METTL3_EV_vs_WT_F08.20115.20115.4 5.07E-05 11/132 K.DFDFESANAQFNK[136.11]EEIDR[166.11]EFHNK[136.11].L "sp|Q8ND56|LS14A_HUMAN,tr|A0A140TA76|A0A140TA76_HUMAN,tr|K7EMZ9|K7EMZ9_HUMAN" 3 2855.2997 1.38 121740 20115 4 2856.292979 714.8322 Protein LSM14 homolog A OS=Homo sapiens OX=9606 GN=LSM14A PE=1 SV=3 4.43 3320.5 - 242552 - - - 347.8647 - 2.067 0.539 - 31.1 1 2 2 0.9933 23 0 0 0 3.41E+06 2.47E+06 - - - 3.8776 0.9999 221125_WJC_METTL3_EV_vs_WT_F08.20116.20116.4 3.20E-10 16/102 R.SPSELFAQHIVTIVHHVK[136.11].E "sp|Q9Y2W1|TR150_HUMAN,tr|A0A3B3ITZ9|A0A3B3ITZ9_HUMAN" 2 2049.1251 2.63 121741 20116 4 2049.130541 513.2886 Thyroid hormone receptor-associated protein 3 OS=Homo sapiens OX=9606 GN=THRAP3 PE=1 SV=2 6.78 3320.7 - 482880 - - - 2.6577 - 3.076 0.532 - 195 1 2 0 0.0054 18 0 0 0 8.36E+08 3.18E+08 - - - 4.2399 0.9995 221125_WJC_METTL3_EV_vs_WT_F08.20117.20117.3 0.000295 Dec-44 R.AR[166.11]FEELNADLFR[166.11].G "sp|P54652|HSP72_HUMAN,sp|P11142|HSP7C_HUMAN,tr|E9PNE6|E9PNE6_HUMAN,tr|A8K7Q2|A8K7Q2_HUMAN,tr|E9PKE3|E9PKE3_HUMAN,tr|E9PN89|E9PN89_HUMAN" 6 1499.7636 0.18 121742 20117 3 1499.766971 500.9285 Heat shock-related 70 kDa protein 2 OS=Homo sapiens OX=9606 GN=HSPA2 PE=1 SV=1 4.68 3320.8 - 467238 - - - 2.2697 - 2.112 0.479 - 283.6 1 2 1 0.0034 12 0 0 0 4.36E+06 2.46E+07 - - - 5.9518 0.9999 221125_WJC_METTL3_EV_vs_WT_F08.20121.20121.4 1.17E-06 18/102 K.YHIDLDPHFNDILGQHSR.K "sp|P19784|CSK22_HUMAN,tr|H3BNI9|H3BNI9_HUMAN,tr|H3BSA1|H3BSA1_HUMAN" 3 2176.045 1.11 121744 20121 4 2176.050459 545.0185 Casein kinase II subunit alpha' OS=Homo sapiens OX=9606 GN=CSNK2A2 PE=1 SV=1 5.71 3321.3 - 242704 - - - 2.5087 - 2.786 0.537 - 226.8 1 2 0 0.0055 18 0 0 0 2.43E+07 2.19E+07 - - - 4.2495 1 221125_WJC_METTL3_EV_vs_WT_F08.20124.20124.3 1.15E-15 23/116 R.SNGETPAVDIGAADLAHAQQQQQQALQVAR.Q "sp|Q9H334|FOXP1_HUMAN,tr|G5E965|G5E965_HUMAN,tr|A0A3B3IRY1|A0A3B3IRY1_HUMAN,tr|A0A087WVT2|A0A087WVT2_HUMAN,tr|A0A3B3IRS5|A0A3B3IRS5_HUMAN,tr|A0A3B3IST0|A0A3B3IST0_HUMAN,tr|A0A3B3ISQ7|A0A3B3ISQ7_HUMAN,tr|C9J0F0|C9J0F0_HUMAN,tr|A0A3B3IU15|A0A3B3IU15_HUMAN,tr|A0A3B3IU08|A0A3B3IU08_HUMAN,tr|A0A3B3IST6|A0A3B3IST6_HUMAN" 11 3114.5443 999 121747 20124 3 3114.555043 1039.1887 Forkhead box protein P1 OS=Homo sapiens OX=9606 GN=FOXP1 PE=1 SV=1 4.53 3321.7 - 288113 - - - 3.4647 - 4.909 0.752 - 276.4 1 2 0 0.0108 30 0 0 0 1.23E+07 0.00E+00 - - - 10.5815 1 221125_WJC_METTL3_EV_vs_WT_F08.20127.20127.3 5.90E-11 20/72 R.TSQNSELNNMQDLVEDYKK.K sp|P35908|K22E_HUMAN 1 2255.0376 999 121749 20127 3 2256.028254 752.6865 "Keratin, type II cytoskeletal 2 epidermal OS=Homo sapiens OX=9606 GN=KRT2 PE=1 SV=2" 4.32 3322.1 - 1.80E+06 - - - 439.3111 - 3.407 0.66 - 589.5 1 2 0 0.9907 19 0 0 0 1.99E+07 0.00E+00 - - - 8.6356 1 221125_WJC_METTL3_EV_vs_WT_F08.20135.20135.4 1.72E-08 17/150 K.YYQHLYSIHLAEQPEDC[160.03]TMQLADHIK.F "sp|Q14203|DCTN1_HUMAN,tr|A0A804CDA6|A0A804CDA6_HUMAN,tr|E7EX90|E7EX90_HUMAN,tr|A0A7P0Z4C3|A0A7P0Z4C3_HUMAN,tr|Q6AWB1|Q6AWB1_HUMAN" 5 3202.4852 0.8 121754 20135 4 3202.493535 801.6286 Dynactin subunit 1 OS=Homo sapiens OX=9606 GN=DCTN1 PE=1 SV=3 5.21 3323.1 - 271565 - - - 2.6008 - 3.501 0.635 - 169.8 1 2 0 0.0083 26 0 0 0 8.60E+06 1.08E+07 - - - 5.146 0.9995 221125_WJC_METTL3_EV_vs_WT_F08.20146.20146.4 3.39E-09 13/198 K.TPK[136.11]PVEPAASDLEPFTPTDQSVTPEAIAQGGQSK[136.11].T sp|Q14676|MDC1_HUMAN 1 3508.7544 1.85 121760 20146 4 3508.774973 878.1959 Mediator of DNA damage checkpoint protein 1 OS=Homo sapiens OX=9606 GN=MDC1 PE=1 SV=3 4.18 3324.7 - 150302 - - - 5.8565 - 3.121 0.547 - 50.5 1 2 0 0.0205 34 0 0 0 8.67E+06 4.68E+06 - - - 4.3208 0.9999 221125_WJC_METTL3_EV_vs_WT_F08.20151.20151.3 4.60E-09 17/132 K.TPKPVEPAASDLEPFTPTDQSVTPEAIAQGGQSK.T sp|Q14676|MDC1_HUMAN 1 3492.726 1.97 121762 20151 3 3492.738275 1165.2493 Mediator of DNA damage checkpoint protein 1 OS=Homo sapiens OX=9606 GN=MDC1 PE=1 SV=3 4.18 3325.4 - 196765 - - - 3.5076 - 3.279 0.597 - 189.5 1 2 0 0.0123 34 0 0 0 5.84E+06 2.96E+06 - - - 7.9247 0.9035 221125_WJC_METTL3_EV_vs_WT_F08.20153.20153.3 0.000538 11/100 K.NGFSSVQATQLQTTQSVEGATGSAVK.S "sp|Q14157|UBP2L_HUMAN,tr|F8W726|F8W726_HUMAN" 2 2595.2776 1.25 121764 20153 3 2596.265383 866.0998 Ubiquitin-associated protein 2-like OS=Homo sapiens OX=9606 GN=UBAP2L PE=1 SV=2 6 3325.7 - 464497 - - - 380.5928 - 2.666 0.409 - 118.3 1 2 0 0.9877 26 0 0 0 1.16E+06 9.27E+05 - - - 5.0823 1 221125_WJC_METTL3_EV_vs_WT_F08.20156.20156.3 3.86E-14 19/68 R.SPSELFAQHIVTIVHHVK.E "sp|Q9Y2W1|TR150_HUMAN,tr|A0A3B3ITZ9|A0A3B3ITZ9_HUMAN" 2 2041.1109 2.59 121765 20156 3 2041.116071 681.3776 Thyroid hormone receptor-associated protein 3 OS=Homo sapiens OX=9606 GN=THRAP3 PE=1 SV=2 6.78 3326.1 - 915089 - - - 2.5359 - 3.832 0.665 - 483.4 1 2 0 0.0052 18 0 0 0 1.34E+08 5.16E+07 - - - 9.2978 1 221125_WJC_METTL3_EV_vs_WT_F08.20158.20158.3 4.39E-06 13/144 R.GQPGNAYDGAGQPSAAYLSMSQGAVANANSTPPPYER.T sp|Q96PK6|RBM14_HUMAN 1 3693.6754 2.74 121767 20158 3 3693.673226 1232.2324 RNA-binding protein 14 OS=Homo sapiens OX=9606 GN=RBM14 PE=1 SV=2 4.37 3326.4 - 212485 - - - -0.5891 - 2.732 0.595 - 44.6 1 2 0 -0.0022 37 0 0 0 4.02E+08 1.47E+08 - - - 7.4853 0.998 221125_WJC_METTL3_EV_vs_WT_F08.20160.20160.3 0.000337 Oct-44 R.ARFEELNADLFR.G "sp|P54652|HSP72_HUMAN,sp|P11142|HSP7C_HUMAN,tr|E9PNE6|E9PNE6_HUMAN,tr|A8K7Q2|A8K7Q2_HUMAN,tr|E9PKE3|E9PKE3_HUMAN,tr|E9PN89|E9PN89_HUMAN" 6 1479.747 0.17 121769 20160 3 1479.751165 494.2563 Heat shock-related 70 kDa protein 2 OS=Homo sapiens OX=9606 GN=HSPA2 PE=1 SV=1 4.68 3326.6 - 169356 - - - 2.7964 - 2.145 0.386 - 191.5 1 2 1 0.0041 12 0 0 0 4.27E+06 2.46E+07 - - - 4.9577 1 221125_WJC_METTL3_EV_vs_WT_F08.20164.20164.4 1.16E-06 24/216 R.GQPGNAYDGAGQPSAAYLSMSQGAVANANSTPPPYER.T sp|Q96PK6|RBM14_HUMAN 1 3693.6754 2.27 121771 20164 4 3693.673435 924.4261 RNA-binding protein 14 OS=Homo sapiens OX=9606 GN=RBM14 PE=1 SV=2 4.37 3327.2 - 408032 - - - -0.5325 - 4.273 0.654 - 151.8 1 2 0 -0.002 37 0 0 0 4.00E+08 1.76E+08 - - - 5.3436 0.9997 221125_WJC_METTL3_EV_vs_WT_F08.20166.20166.4 0.000258 9/174 R.SNGETPAVDIGAADLAHAQQQQQQALQVAR.Q "sp|Q9H334|FOXP1_HUMAN,tr|G5E965|G5E965_HUMAN,tr|A0A3B3IRY1|A0A3B3IRY1_HUMAN,tr|A0A087WVT2|A0A087WVT2_HUMAN,tr|A0A3B3IRS5|A0A3B3IRS5_HUMAN,tr|A0A3B3IST0|A0A3B3IST0_HUMAN,tr|A0A3B3ISQ7|A0A3B3ISQ7_HUMAN,tr|C9J0F0|C9J0F0_HUMAN,tr|A0A3B3IU15|A0A3B3IU15_HUMAN,tr|A0A3B3IU08|A0A3B3IU08_HUMAN,tr|A0A3B3IST6|A0A3B3IST6_HUMAN" 11 3114.5443 1.58 121773 20166 4 3114.550789 779.6433 Forkhead box protein P1 OS=Homo sapiens OX=9606 GN=FOXP1 PE=1 SV=1 4.53 3327.4 - 239556 - - - 2.0989 - 1.93 0.396 - 41 1 2 0 0.0065 30 0 0 0 4.94E+06 3.13E+06 - - - 2.8722 0.9999 221125_WJC_METTL3_EV_vs_WT_F08.20173.20173.3 1.49E-07 Dec-56 R.STSHK[136.11]PDEIYGMIER[166.11].L sp|Q86U44|MTA70_HUMAN 1 1779.8581 0.04 121777 20173 3 1779.863463 594.2933 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 5.42 3328.5 - 232248 - - - 3.039 - 2.672 0.555 - 191.8 1 2 0 0.0054 15 0 0 0 4.99E+05 1.35E+07 - - - 7.2908 1 221125_WJC_METTL3_EV_vs_WT_F08.20176.20176.3 3.93E-15 17/144 R.GQPGNAYDGAGQPSAAYLSMSQGAVANANSTPPPYER[166.11].T sp|Q96PK6|RBM14_HUMAN 1 3703.6837 2.74 121778 20176 3 3703.686317 1235.5685 RNA-binding protein 14 OS=Homo sapiens OX=9606 GN=RBM14 PE=1 SV=2 4.37 3328.9 - 250822 - - - 0.7142 - 4.015 0.743 - 91.3 1 2 0 0.0026 37 0 0 0 4.02E+08 1.47E+08 - - - 10.021 0.8129 221125_WJC_METTL3_EV_vs_WT_F08.20179.20179.3 0.0632 Jul-44 F.AQHIVTIVHHVK[136.11].E "sp|Q9Y2W1|TR150_HUMAN,tr|A0A3B3ITZ9|A0A3B3ITZ9_HUMAN" 2 1388.8132 3.21 121781 20179 3 1388.815795 463.945 Thyroid hormone receptor-associated protein 3 OS=Homo sapiens OX=9606 GN=THRAP3 PE=1 SV=2 8.81 3329.2 - 102281 - - - 1.8663 - 1.315 0.347 - 62.2 1 1 0 0.0026 12 0 0 0 4.47E+07 1.39E+07 - - - 3.167 0.9985 221125_WJC_METTL3_EV_vs_WT_F08.20183.20183.3 2.31E-06 13/44 F.AQHIVTIVHHVK.E "sp|Q9Y2W1|TR150_HUMAN,tr|A0A3B3ITZ9|A0A3B3ITZ9_HUMAN" 2 1380.799 2.42 121783 20183 3 1380.799085 461.2736 Thyroid hormone receptor-associated protein 3 OS=Homo sapiens OX=9606 GN=THRAP3 PE=1 SV=2 8.81 3329.8 - 242205 - - - 0.0594 - 2.472 0.582 - 204.6 1 1 0 0.0001 12 0 0 0 2.48E+07 1.02E+07 - - - 7.5373 1 221125_WJC_METTL3_EV_vs_WT_F08.20186.20186.3 5.37E-12 22/68 R.SPSELFAQHIVTIVHHVK[136.11].E "sp|Q9Y2W1|TR150_HUMAN,tr|A0A3B3ITZ9|A0A3B3ITZ9_HUMAN" 2 2049.1251 2.59 121784 20186 3 2049.126316 684.049 Thyroid hormone receptor-associated protein 3 OS=Homo sapiens OX=9606 GN=THRAP3 PE=1 SV=2 6.78 3330.2 - 756303 - - - 0.5959 - 3.884 0.679 - 784.8 1 2 0 0.0012 18 0 0 0 1.46E+08 5.65E+07 - - - 9.4886 0.9857 221125_WJC_METTL3_EV_vs_WT_F08.20188.20188.3 2.29E-05 Dec-48 L.DGIHLLDPDVVAR[166.11].F sp|Q86U44|MTA70_HUMAN 1 1428.76 0.01 121786 20188 3 1428.760773 477.2606 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 4.41 3330.4 - 425488 - - - 0.5074 - 2.528 0.344 - 317.6 1 1 0 0.0007 13 0 0 0 9.34E+04 1.14E+07 - - - 4.8896 1 221125_WJC_METTL3_EV_vs_WT_F08.20189.20189.4 5.39E-07 16/162 K.EMEPLGWIHTQPNESPQLSPQDVTTHAK.L sp|Q6P2Q9|PRP8_HUMAN 1 3169.5139 1.47 121787 20189 4 3169.517882 793.3857 Pre-mRNA-processing-splicing factor 8 OS=Homo sapiens OX=9606 GN=PRPF8 PE=1 SV=2 4.8 3330.6 - 344209 - - - 1.268 - 3.014 0.523 - 106.2 1 2 0 0.004 28 0 0 0 5.17E+07 3.52E+07 - - - 4.1196 1 221125_WJC_METTL3_EV_vs_WT_F08.20205.20205.4 4.12E-12 24/216 R.GQPGNAYDGAGQPSAAYLSMSQGAVANANSTPPPYER[166.11].T sp|Q96PK6|RBM14_HUMAN 1 3703.6837 2.27 121795 20205 4 3703.676564 926.9282 RNA-binding protein 14 OS=Homo sapiens OX=9606 GN=RBM14 PE=1 SV=2 4.37 3332.6 - 993406 - - - -1.9192 - 4.567 0.664 - 161.4 1 2 0 -0.0071 37 0 0 0 3.99E+08 1.76E+08 - - - 5.4488 0.9996 221125_WJC_METTL3_EV_vs_WT_F08.20210.20210.4 2.28E-05 17/132 K.AENGKLVINGNPITIFQERDPSK.L sp|P04406|G3P_HUMAN 1 2539.3395 1.51 121797 20210 4 2539.347883 635.8421 Glyceraldehyde-3-phosphate dehydrogenase OS=Homo sapiens OX=9606 GN=GAPDH PE=1 SV=3 6.23 3333.4 - 338973 - - - 3.3205 - 3.317 0.519 - 184.8 1 2 2 0.0084 23 0 0 0 1.29E+08 8.55E+07 - - - 4.1295 1 221125_WJC_METTL3_EV_vs_WT_F08.20211.20211.4 1.05E-09 26/126 K.HTDESLGDC[160.03]SFLNTC[160.03]FHMDTC[160.03]K[136.11].Y "sp|Q86U44|MTA70_HUMAN,tr|H0YFV6|H0YFV6_HUMAN" 2 2682.0698 0.06 121798 20211 4 2682.066674 671.5247 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 4.64 3333.5 - 1.91E+06 - - - -1.1819 - 4.883 0.677 - 639.8 1 2 0 -0.0032 22 0 0 0 6.27E+06 1.12E+08 - - - 5.6366 0.9994 221125_WJC_METTL3_EV_vs_WT_F08.20212.20212.3 0.0819 14/52 R.NKLNDLEEALQQAK.E sp|P35908|K22E_HUMAN 1 1612.842 999 121799 20212 3 1612.840115 538.6213 "Keratin, type II cytoskeletal 2 epidermal OS=Homo sapiens OX=9606 GN=KRT2 PE=1 SV=2" 4.68 3333.6 - 213300 - - - -1.1997 - 2.437 0.37 - 291 1 2 1 -0.0019 14 0 0 0 3.02E+07 0.00E+00 - - - 5.0318 0.9935 221125_WJC_METTL3_EV_vs_WT_F08.20233.20233.4 2.43E-05 Dec-96 S.PSELFAQHIVTIVHHVK.E "sp|Q9Y2W1|TR150_HUMAN,tr|A0A3B3ITZ9|A0A3B3ITZ9_HUMAN" 2 1954.0789 4.78 121811 20233 4 1954.077096 489.527 Thyroid hormone receptor-associated protein 3 OS=Homo sapiens OX=9606 GN=THRAP3 PE=1 SV=2 7.42 3336.3 - 209243 - - - -0.9058 - 2.361 0.466 - 118.3 1 1 0 -0.0018 17 0 0 0 1.16E+07 2.42E+06 - - - 3.5798 0.9964 221125_WJC_METTL3_EV_vs_WT_F08.20234.20234.3 2.39E-05 16/128 R.SDSPVPTAPTSGGPK[136.11]PSTASAVPELATDPELEK[136.11].K "sp|Q86U44|MTA70_HUMAN,tr|B4E349|B4E349_HUMAN,tr|F5H6D8|F5H6D8_HUMAN,tr|B4DTN4|B4DTN4_HUMAN" 4 3248.6271 0 121812 20234 3 3249.620974 1083.883 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 4.18 3336.4 - 558505 - - - 305.9372 - 3.001 0.494 - 101.3 1 2 0 0.9939 33 0 0 0 1.85E+05 4.99E+07 - - - 6.3006 0.9998 221125_WJC_METTL3_EV_vs_WT_F08.20244.20244.4 1.73E-06 18/162 K.EMEPLGWIHTQPNESPQLSPQDVTTHAK[136.11].L sp|Q6P2Q9|PRP8_HUMAN 1 3177.5281 1.63 121818 20244 4 3177.52354 795.3893 Pre-mRNA-processing-splicing factor 8 OS=Homo sapiens OX=9606 GN=PRPF8 PE=1 SV=2 4.8 3337.7 - 1.24E+06 - - - -1.4234 - 3.315 0.367 - 131.5 1 2 0 -0.0045 28 0 0 0 5.75E+07 3.54E+07 - - - 2.7912 0.9999 221125_WJC_METTL3_EV_vs_WT_F08.20246.20246.4 1.21E-11 20/108 K.ER[166.11]VEAVNMAEGIIHDTETK[136.11].M "sp|P38646|GRP75_HUMAN,tr|A0A7I2V2S7|A0A7I2V2S7_HUMAN,tr|A0A7I2V2G2|A0A7I2V2G2_HUMAN,tr|A0A7I2V3F7|A0A7I2V3F7_HUMAN,tr|A0A7I2YQB2|A0A7I2YQB2_HUMAN,tr|D6RCD7|D6RCD7_HUMAN" 6 2159.0648 0.42 121819 20246 4 2159.062808 540.7735 "Stress-70 protein, mitochondrial OS=Homo sapiens OX=9606 GN=HSPA9 PE=1 SV=2" 4.57 3338 - 384897 - - - -0.9009 - 3.986 0.607 - 333 1 2 1 -0.0019 19 0 0 0 5.23E+07 1.26E+08 - - - 4.9766 0.9841 221125_WJC_METTL3_EV_vs_WT_F08.20248.20248.4 0.619 9/192 R.K[136.11]ESESC[160.03]DC[160.03]LQGFQLTHSLGGGTGSGMGTLLISK[136.11].L "sp|Q9BVA1|TBB2B_HUMAN,sp|Q13885|TBB2A_HUMAN" 2 3470.6451 1.62 121820 20248 4 3470.640236 868.6685 Tubulin beta-2B chain OS=Homo sapiens OX=9606 GN=TUBB2B PE=1 SV=1 5.44 3338.2 - 1.73E+06 - - - -1.3989 - 1.287 0.196 - 27.6 1 2 0 -0.0049 33 0 0 0 4.82E+07 2.97E+07 - - - 1.0063 1 221125_WJC_METTL3_EV_vs_WT_F08.20253.20253.3 3.03E-08 22/48 R.KIEEIKDFLLTAR.R "sp|P63173|RL38_HUMAN,tr|J3KT73|J3KT73_HUMAN,tr|J3QL01|J3QL01_HUMAN,tr|J3KSP2|J3KSP2_HUMAN" 4 1574.9032 1.11 121823 20253 3 1574.902362 525.975 60S ribosomal protein L38 OS=Homo sapiens OX=9606 GN=RPL38 PE=1 SV=2 6.18 3338.9 - 866660 - - - -0.5283 - 3.196 0.576 - 703.8 1 2 1 -0.0008 13 0 0 0 2.17E+08 1.95E+08 - - - 8.1118 0.9982 221125_WJC_METTL3_EV_vs_WT_F08.20255.20255.4 0.00056 13/72 R.K[136.11]IEEIK[136.11]DFLLTAR[166.11].R "sp|P63173|RL38_HUMAN,tr|J3KT73|J3KT73_HUMAN,tr|J3QL01|J3QL01_HUMAN,tr|J3KSP2|J3KSP2_HUMAN" 4 1600.9399 1.13 121825 20255 4 1600.939462 401.2422 60S ribosomal protein L38 OS=Homo sapiens OX=9606 GN=RPL38 PE=1 SV=2 6.18 3339.2 - 365347 - - - -0.2505 - 2.246 0.331 - 151.9 1 2 1 -0.0004 13 0 0 0 4.51E+07 3.98E+07 - - - 2.4069 1 221125_WJC_METTL3_EV_vs_WT_F08.20258.20258.3 3.41E-17 32/72 K.ER[166.11]VEAVNMAEGIIHDTETK[136.11].M "sp|P38646|GRP75_HUMAN,tr|A0A7I2V2S7|A0A7I2V2S7_HUMAN,tr|A0A7I2V2G2|A0A7I2V2G2_HUMAN,tr|A0A7I2V3F7|A0A7I2V3F7_HUMAN,tr|A0A7I2YQB2|A0A7I2YQB2_HUMAN,tr|D6RCD7|D6RCD7_HUMAN" 6 2159.0648 0.39 121826 20258 3 2159.06398 720.6955 "Stress-70 protein, mitochondrial OS=Homo sapiens OX=9606 GN=HSPA9 PE=1 SV=2" 4.57 3339.6 - 1.20E+06 - - - -0.358 - 5.788 0.628 - 1629.8 1 2 1 -0.0008 19 0 0 0 5.15E+07 1.34E+08 - - - 9.855 1 221125_WJC_METTL3_EV_vs_WT_F08.20259.20259.3 5.25E-09 23/72 K.ERVEAVNMAEGIIHDTETK.M "sp|P38646|GRP75_HUMAN,tr|A0A7I2V2S7|A0A7I2V2S7_HUMAN,tr|A0A7I2V2G2|A0A7I2V2G2_HUMAN,tr|A0A7I2V3F7|A0A7I2V3F7_HUMAN,tr|A0A7I2YQB2|A0A7I2YQB2_HUMAN,tr|D6RCD7|D6RCD7_HUMAN" 6 2141.0423 0.39 121827 20259 3 2141.041294 714.688 "Stress-70 protein, mitochondrial OS=Homo sapiens OX=9606 GN=HSPA9 PE=1 SV=2" 4.57 3339.7 - 322558 - - - -0.4619 - 4.768 0.632 - 639 1 2 1 -0.001 19 0 0 0 5.15E+07 1.34E+08 - - - 9.4232 1 221125_WJC_METTL3_EV_vs_WT_F08.20265.20265.3 2.55E-05 21/48 R.K[136.11]IEEIK[136.11]DFLLTAR[166.11].R "sp|P63173|RL38_HUMAN,tr|J3KT73|J3KT73_HUMAN,tr|J3QL01|J3QL01_HUMAN,tr|J3KSP2|J3KSP2_HUMAN" 4 1600.9399 1.11 121831 20265 3 1600.938267 534.6539 60S ribosomal protein L38 OS=Homo sapiens OX=9606 GN=RPL38 PE=1 SV=2 6.18 3340.5 - 4.74E+06 - - - -0.9969 - 3.175 0.599 - 609 1 2 1 -0.0016 13 0 0 0 2.17E+08 1.95E+08 - - - 8.3502 0.9999 221125_WJC_METTL3_EV_vs_WT_F08.20272.20272.4 1.44E-08 18/108 K.GLEEITVHNKDEVYQILEK.G "sp|P52732|KIF11_HUMAN,tr|A0A7I2YQY4|A0A7I2YQY4_HUMAN,tr|A0A7I2V3A9|A0A7I2V3A9_HUMAN,tr|A0A7I2V3V3|A0A7I2V3V3_HUMAN" 4 2256.1638 7.41 121834 20272 4 2256.162887 565.0482 Kinesin-like protein KIF11 OS=Homo sapiens OX=9606 GN=KIF11 PE=1 SV=2 4.57 3341.3 - 954264 - - - -0.3949 - 3.612 0.516 - 325.5 1 2 1 -0.0009 19 0 0 0 3.93E+07 5.31E+06 - - - 4.1515 0.9999 221125_WJC_METTL3_EV_vs_WT_F08.20273.20273.4 0.000149 15/210 R.SVGDGETVEFDVVEGEK[136.11]GAEAANVTGPGGVPVQGSK[136.11].Y "sp|P67809|YBOX1_HUMAN,tr|H0Y449|H0Y449_HUMAN" 2 3487.6926 2.04 121835 20273 4 3487.685571 872.9304 Y-box-binding protein 1 OS=Homo sapiens OX=9606 GN=YBX1 PE=1 SV=3 4 3341.4 - 823136 - - - -2.0016 - 2.649 0.546 - 49.9 1 2 1 -0.007 36 0 0 0 2.67E+07 1.31E+07 - - - 4.2636 1 221125_WJC_METTL3_EV_vs_WT_F08.20275.20275.2 5.98E-09 17/24 R.KIEEIKDFLLTAR.R "sp|P63173|RL38_HUMAN,tr|J3KT73|J3KT73_HUMAN,tr|J3QL01|J3QL01_HUMAN,tr|J3KSP2|J3KSP2_HUMAN" 4 1574.9032 0.85 121837 20275 2 1574.901193 788.4589 60S ribosomal protein L38 OS=Homo sapiens OX=9606 GN=RPL38 PE=1 SV=2 6.18 3341.7 - 417573 - - - -1.2706 - 3.467 0.598 - 1165.1 1 2 1 -0.002 13 0 0 0 7.31E+06 8.61E+06 - - - 6.6481 1 221125_WJC_METTL3_EV_vs_WT_F08.20284.20284.3 1.07E-10 18/140 R.SVGDGETVEFDVVEGEK[136.11]GAEAANVTGPGGVPVQGSK[136.11].Y "sp|P67809|YBOX1_HUMAN,tr|H0Y449|H0Y449_HUMAN" 2 3487.6926 1.26 121840 20284 3 3487.689655 1163.5715 Y-box-binding protein 1 OS=Homo sapiens OX=9606 GN=YBX1 PE=1 SV=3 4 3343.1 - 1.05E+06 - - - -0.8306 - 3.997 0.684 - 93.2 1 2 1 -0.0029 36 0 0 0 2.25E+07 1.78E+07 - - - 9.3528 0.9996 221125_WJC_METTL3_EV_vs_WT_F08.20290.20290.4 3.27E-08 19/108 K.ERVEAVNMAEGIIHDTETK.M "sp|P38646|GRP75_HUMAN,tr|A0A7I2V2S7|A0A7I2V2S7_HUMAN,tr|A0A7I2V2G2|A0A7I2V2G2_HUMAN,tr|A0A7I2V3F7|A0A7I2V3F7_HUMAN,tr|A0A7I2YQB2|A0A7I2YQB2_HUMAN,tr|D6RCD7|D6RCD7_HUMAN" 6 2141.0423 0.41 121843 20290 4 2141.035431 536.2678 "Stress-70 protein, mitochondrial OS=Homo sapiens OX=9606 GN=HSPA9 PE=1 SV=2" 4.57 3343.8 - 1.40E+06 - - - -3.2003 - 3.031 0.514 - 263.7 1 2 1 -0.0069 19 0 0 0 5.20E+07 1.26E+08 - - - 4.0731 1 221125_WJC_METTL3_EV_vs_WT_F08.20300.20300.4 3.48E-11 19/102 R.SPSELFAQHIVTIVHHVK.E "sp|Q9Y2W1|TR150_HUMAN,tr|A0A3B3ITZ9|A0A3B3ITZ9_HUMAN" 2 2041.1109 2.77 121849 20300 4 2041.104988 511.285 Thyroid hormone receptor-associated protein 3 OS=Homo sapiens OX=9606 GN=THRAP3 PE=1 SV=2 6.78 3344.9 - 1.76E+07 - - - -2.894 - 3.435 0.6 - 254.6 1 2 0 -0.0059 18 0 0 0 1.04E+09 3.74E+08 - - - 4.8695 1 221125_WJC_METTL3_EV_vs_WT_F08.20342.20342.4 4.34E-10 20/210 K.GSPEFPAQETPTTFPEEAPTVSPAVAQSNSSEEEAR.E "sp|Q5JSZ5|PRC2B_HUMAN,tr|A0A804HIM8|A0A804HIM8_HUMAN" 2 3773.718 3.91 121862 20342 4 3773.712558 944.4368 Protein PRRC2B OS=Homo sapiens OX=9606 GN=PRRC2B PE=1 SV=2 3.83 3350.6 - 1.33E+06 - - - -1.4521 - 3.476 0.636 - 111 1 2 0 -0.0055 36 0 0 0 4.46E+07 1.14E+07 - - - 5.1275 1 221125_WJC_METTL3_EV_vs_WT_F08.20344.20344.4 1.38E-08 19/102 R.SPSELFAQHIVTIVHHVK[136.11].E "sp|Q9Y2W1|TR150_HUMAN,tr|A0A3B3ITZ9|A0A3B3ITZ9_HUMAN" 2 2049.1251 2.78 121863 20344 4 2049.120615 513.2886 Thyroid hormone receptor-associated protein 3 OS=Homo sapiens OX=9606 GN=THRAP3 PE=1 SV=2 6.78 3350.8 - 4.73E+06 - - - -2.1863 - 3.133 0.591 - 298.4 1 2 0 -0.0045 18 0 0 0 9.41E+08 3.38E+08 - - - 4.76 0.9964 221125_WJC_METTL3_EV_vs_WT_F08.20354.20354.3 0.00257 13/60 K.QK[136.11]LEDK[136.11]VENLVDQLNK[136.11].S "sp|Q15643|TRIPB_HUMAN,tr|H0YJ97|H0YJ97_HUMAN" 2 1936.0692 1.22 121868 20354 3 1936.062904 646.3637 Thyroid receptor-interacting protein 11 OS=Homo sapiens OX=9606 GN=TRIP11 PE=1 SV=3 4.78 3352.1 - 3.05E+06 - - - -3.2292 - 2.573 0.332 - 146.4 1 2 2 -0.0063 16 0 0 0 2.87E+08 2.36E+08 - - - 4.6647 0.9987 221125_WJC_METTL3_EV_vs_WT_F08.20356.20356.3 0.0214 Sep-60 K.QKLEDKVENLVDQLNK.S "sp|Q15643|TRIPB_HUMAN,tr|H0YJ97|H0YJ97_HUMAN" 2 1912.0266 1.22 121870 20356 3 1912.029442 638.3495 Thyroid receptor-interacting protein 11 OS=Homo sapiens OX=9606 GN=TRIP11 PE=1 SV=3 4.78 3352.3 - 3.52E+06 - - - 1.5094 - 2.262 0.357 - 130.4 1 2 2 0.0029 16 0 0 0 2.87E+08 2.36E+08 - - - 4.6138 0.9999 221125_WJC_METTL3_EV_vs_WT_F08.20363.20363.4 2.36E-07 18/108 K.IKSDFFELLSNHHLDSQSR.W "sp|O14776|TCRG1_HUMAN,tr|A0A7P0T8N8|A0A7P0T8N8_HUMAN,tr|G3V220|G3V220_HUMAN" 3 2272.1236 0.58 121873 20363 4 2272.123832 569.0382 Transcription elongation regulator 1 OS=Homo sapiens OX=9606 GN=TCERG1 PE=1 SV=2 6 3353.2 - 433053 - - - 0.0823 - 2.986 0.548 - 128.1 1 2 1 0.0002 19 0 0 0 8.26E+06 1.41E+07 - - - 4.3658 0.9998 221125_WJC_METTL3_EV_vs_WT_F08.20367.20367.4 1.32E-10 19/108 K.IK[136.11]SDFFELLSNHHLDSQSR[166.11].W "sp|O14776|TCRG1_HUMAN,tr|A0A7P0T8N8|A0A7P0T8N8_HUMAN,tr|G3V220|G3V220_HUMAN" 3 2290.1461 0.58 121876 20367 4 2290.143516 573.5438 Transcription elongation regulator 1 OS=Homo sapiens OX=9606 GN=TCERG1 PE=1 SV=2 6 3353.7 - 680028 - - - -1.1349 - 3.99 0.474 - 351.4 1 2 1 -0.0026 19 0 0 0 8.26E+06 1.41E+07 - - - 3.8191 0.9999 221125_WJC_METTL3_EV_vs_WT_F08.20371.20371.4 3.98E-06 17/120 K.DGNVLLHEMQIQHPTASLIAK[136.11].V sp|P40227|TCPZ_HUMAN 1 2322.2246 0.52 121878 20371 4 2322.220164 581.5634 T-complex protein 1 subunit zeta OS=Homo sapiens OX=9606 GN=CCT6A PE=1 SV=3 5.99 3354.2 - 1.13E+06 - - - -1.8891 - 3.357 0.48 - 171.1 1 2 0 -0.0044 21 0 0 0 7.97E+06 1.53E+07 - - - 3.8031 1 221125_WJC_METTL3_EV_vs_WT_F08.20389.20389.3 1.82E-12 27/144 R.GQPGNAYDGAGQPSAAYLSMSQGAVANANSTPPPYER.T sp|Q96PK6|RBM14_HUMAN 1 3693.6754 2.74 121887 20389 3 3693.672047 1232.2324 RNA-binding protein 14 OS=Homo sapiens OX=9606 GN=RBM14 PE=1 SV=2 4.37 3356.6 - 1.43E+06 - - - -0.9083 - 5.1 0.728 - 288.8 1 2 0 -0.0034 37 0 0 0 4.02E+08 1.47E+08 - - - 10.4038 1 221125_WJC_METTL3_EV_vs_WT_F08.20396.20396.4 9.99E-13 29/216 R.GQPGNAYDGAGQPSAAYLSMSQGAVANANSTPPPYER.T sp|Q96PK6|RBM14_HUMAN 1 3693.6754 2.27 121893 20396 4 3693.677339 924.4261 RNA-binding protein 14 OS=Homo sapiens OX=9606 GN=RBM14 PE=1 SV=2 4.37 3357.4 - 1.28E+06 - - - 0.5244 - 4.222 0.7 - 229.7 1 2 0 0.0019 37 0 0 0 4.00E+08 1.76E+08 - - - 5.7405 0.9858 221125_WJC_METTL3_EV_vs_WT_F08.20400.20400.4 1.15E-06 16/114 A.TISANGDKEIGNIISDAMKK.V "sp|P10809|CH60_HUMAN,tr|A0A7I2V599|A0A7I2V599_HUMAN,tr|E7EXB4|E7EXB4_HUMAN,tr|A0A7I2YQ71|A0A7I2YQ71_HUMAN,tr|E7ESH4|E7ESH4_HUMAN,tr|A0A7I2V5M1|A0A7I2V5M1_HUMAN,tr|A0A7I2V5K3|A0A7I2V5K3_HUMAN,tr|A0A7I2V369|A0A7I2V369_HUMAN" 8 2104.0834 1.19 121896 20400 4 2104.086001 527.0281 "60 kDa heat shock protein, mitochondrial OS=Homo sapiens OX=9606 GN=HSPD1 PE=1 SV=2" 5.79 3357.9 - 847974 - - - 1.2271 - 2.681 0.515 - 87.6 1 1 1 0.0026 20 0 0 0 1.88E+07 1.59E+07 - - - 4.0375 0.9655 221125_WJC_METTL3_EV_vs_WT_F08.20401.20401.3 1.53E-07 13/72 R.TSQNSELNNMQDLVEDYKK.K sp|P35908|K22E_HUMAN 1 2255.0376 999 121897 20401 3 2256.02436 752.6865 "Keratin, type II cytoskeletal 2 epidermal OS=Homo sapiens OX=9606 GN=KRT2 PE=1 SV=2" 4.32 3358 - 802589 - - - 437.5843 - 2.894 0.588 - 252.1 1 2 0 0.9868 19 0 0 0 1.74E+06 0.00E+00 - - - 7.433 0.9998 221125_WJC_METTL3_EV_vs_WT_F08.20410.20410.3 0.00539 Aug-52 K.K[136.11]GPGEVAGTVTGQK[136.11].R "sp|Q86U44|MTA70_HUMAN,tr|F5H6D8|F5H6D8_HUMAN,tr|H0YFV6|H0YFV6_HUMAN,tr|B4DTN4|B4DTN4_HUMAN" 4 1343.738 0.001 121903 20410 3 1343.738532 448.9199 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 8.59 3359.2 - 121178 - - - 0.4115 - 1.886 0.383 - 96.5 1 2 0 0.0006 14 0 0 0 0.00E+00 7.14E+06 - - - 4.496 0.9993 221125_WJC_METTL3_EV_vs_WT_F08.20417.20417.4 1.73E-08 19/192 R.AAIAPFQSAGSPPELQGLPELHEEC[160.03]EGNHPSAR[166.11].K sp|Q7Z628|ARHG8_HUMAN 1 3505.656 1.6 121908 20417 4 3506.653979 877.4213 Neuroepithelial cell-transforming gene 1 protein OS=Homo sapiens OX=9606 GN=NET1 PE=1 SV=1 4.62 3360 - 414199 - - - 284.6765 - 3.494 0.583 - 137.3 1 2 0 0.998 33 0 0 0 6.98E+06 4.36E+06 - - - 4.3993 1 221125_WJC_METTL3_EV_vs_WT_F08.20418.20418.3 8.76E-11 15/76 A.TISANGDKEIGNIISDAMKK.V "sp|P10809|CH60_HUMAN,tr|A0A7I2V599|A0A7I2V599_HUMAN,tr|E7EXB4|E7EXB4_HUMAN,tr|A0A7I2YQ71|A0A7I2YQ71_HUMAN,tr|E7ESH4|E7ESH4_HUMAN,tr|A0A7I2V5M1|A0A7I2V5M1_HUMAN,tr|A0A7I2V5K3|A0A7I2V5K3_HUMAN,tr|A0A7I2V369|A0A7I2V369_HUMAN" 8 2104.0834 0.87 121909 20418 3 2104.08248 702.3684 "60 kDa heat shock protein, mitochondrial OS=Homo sapiens OX=9606 GN=HSPD1 PE=1 SV=2" 5.79 3360.2 - 307848 - - - -0.4463 - 2.842 0.672 - 128.2 1 1 1 -0.0009 20 0 0 0 5.24E+06 6.00E+06 - - - 8.5659 1 221125_WJC_METTL3_EV_vs_WT_F08.20430.20430.4 1.02E-08 23/192 R.AAIAPFQSAGSPPELQGLPELHEEC[160.03]EGNHPSAR.K sp|Q7Z628|ARHG8_HUMAN 1 3495.6477 1.64 121916 20430 4 3495.643492 874.9192 Neuroepithelial cell-transforming gene 1 protein OS=Homo sapiens OX=9606 GN=NET1 PE=1 SV=1 4.62 3361.7 - 382813 - - - -1.2127 - 3.538 0.652 - 252.7 1 2 0 -0.0042 33 0 0 0 7.14E+06 4.36E+06 - - - 5.2789 0.9204 221125_WJC_METTL3_EV_vs_WT_F08.20436.20436.4 0.146 6/108 R.GLLQDDAHPTLVTYADHSK[136.11].L "sp|Q86U44|MTA70_HUMAN,tr|F5H6D8|F5H6D8_HUMAN,tr|H0YFV6|H0YFV6_HUMAN,tr|B4DTN4|B4DTN4_HUMAN" 4 2088.0367 0.1 121920 20436 4 2088.037623 523.0165 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 5.13 3362.5 - 86131.3 - - - 0.4262 - 1.479 0.127 - 27.7 1 2 0 0.0009 19 0 0 0 7.29E+05 7.04E+06 - - - 0.4636 1 221125_WJC_METTL3_EV_vs_WT_F08.20438.20438.4 5.37E-09 15/144 K.LEHLSVSHNNLTTLHGELSSLPSLR.A "sp|Q13045|FLII_HUMAN,tr|J3KS54|J3KS54_HUMAN,tr|K7EP37|K7EP37_HUMAN,tr|K7EP27|K7EP27_HUMAN" 4 2753.446 0.88 121922 20438 4 2753.452442 689.3688 Protein flightless-1 homolog OS=Homo sapiens OX=9606 GN=FLII PE=1 SV=2 6.27 3362.8 - 286802 - - - 2.3247 - 3.035 0.618 - 149.2 1 2 0 0.0064 25 0 0 0 6.03E+06 6.84E+06 - - - 4.9565 0.9994 221125_WJC_METTL3_EV_vs_WT_F08.20447.20447.4 0.000428 Dec-90 K.K[136.11]EEK[136.11]EDEISLEDLIER[166.11].E sp|Q8WU90|ZC3HF_HUMAN 1 2000.016 0.38 121927 20447 4 2000.020701 501.0113 Zinc finger CCCH domain-containing protein 15 OS=Homo sapiens OX=9606 GN=ZC3H15 PE=1 SV=1 4.17 3364 - 291944 - - - 2.35 - 2.347 0.438 - 115.5 1 2 1 0.0047 16 0 0 0 2.24E+06 5.83E+06 - - - 3.3376 1 221125_WJC_METTL3_EV_vs_WT_F08.20456.20456.3 1.20E-05 16/68 R.SPSELFAQHIVTIVHHVK.E "sp|Q9Y2W1|TR150_HUMAN,tr|A0A3B3ITZ9|A0A3B3ITZ9_HUMAN" 2 2041.1109 2.78 121932 20456 3 2041.114058 681.3776 Thyroid hormone receptor-associated protein 3 OS=Homo sapiens OX=9606 GN=THRAP3 PE=1 SV=2 6.78 3365.2 - 569842 - - - 1.5496 - 3.216 0.549 - 273.3 1 2 0 0.0032 18 0 0 0 2.51E+08 9.03E+07 - - - 7.5687 0.9992 221125_WJC_METTL3_EV_vs_WT_F08.20460.20460.4 0.000111 10/144 K.LEHLSVSHNNLTTLHGELSSLPSLR[166.11].A "sp|Q13045|FLII_HUMAN,tr|J3KS54|J3KS54_HUMAN,tr|K7EP37|K7EP37_HUMAN,tr|K7EP27|K7EP27_HUMAN" 4 2763.4543 0.88 121934 20460 4 2763.463549 691.8709 Protein flightless-1 homolog OS=Homo sapiens OX=9606 GN=FLII PE=1 SV=2 6.27 3365.7 - 187382 - - - 3.3429 - 2.303 0.378 - 47.7 1 2 0 0.0092 25 0 0 0 6.03E+06 6.84E+06 - - - 2.7789 1 221125_WJC_METTL3_EV_vs_WT_F08.20463.20463.4 1.06E-11 27/126 K.HTDESLGDC[160.03]SFLNTC[160.03]FHMDTC[160.03]K[136.11].Y "sp|Q86U44|MTA70_HUMAN,tr|H0YFV6|H0YFV6_HUMAN" 2 2682.0698 0.16 121935 20463 4 2683.065942 671.5247 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 4.64 3366.2 - 1.21E+06 - - - 371.3915 - 4.698 0.739 - 589.4 1 2 0 0.9961 22 0 0 0 3.97E+06 2.49E+07 - - - 5.8886 0.989 221125_WJC_METTL3_EV_vs_WT_F08.20489.20489.4 0.0758 7/144 K.FSGDLDDQTC[160.03]REDLHILFSNHGEIK.W sp|P05455|LA_HUMAN 1 2945.3614 0.96 121949 20489 4 2945.369969 737.3476 Lupus La protein OS=Homo sapiens OX=9606 GN=SSB PE=1 SV=2 4.51 3369.8 - 112091 - - - 2.9144 - 1.381 0.316 - 22 1 2 1 0.0086 25 0 0 0 2.94E+06 3.07E+06 - - - 2.0768 0.9991 221125_WJC_METTL3_EV_vs_WT_F08.20495.20495.4 0.000548 Sep-96 R.DLIGHIVEFSQDQHGSR[166.11].F "sp|Q8TB72|PUM2_HUMAN,tr|A0A0C4DG68|A0A0C4DG68_HUMAN" 2 1946.9474 1.43 121954 20495 4 1946.956231 487.7441 Pumilio homolog 2 OS=Homo sapiens OX=9606 GN=PUM2 PE=1 SV=2 5.21 3370.6 - 89713.8 - - - 4.5317 - 1.921 0.435 - 36.5 1 2 0 0.0088 17 0 0 0 2.51E+07 1.76E+07 - - - 3.2365 0.9995 221125_WJC_METTL3_EV_vs_WT_F08.20499.20499.3 1.58E-05 Sep-92 K.SQGLSQLYHNQSQGLLSQLQGQSK.D "sp|P78344|IF4G2_HUMAN,tr|D3DQV9|D3DQV9_HUMAN" 2 2628.3256 2.06 121956 20499 3 2628.338591 877.1158 Eukaryotic translation initiation factor 4 gamma 2 OS=Homo sapiens OX=9606 GN=EIF4G2 PE=1 SV=1 8.33 3371.1 - 222981 - - - 4.9457 - 2.496 0.51 - 75 1 2 0 0.013 24 0 0 0 9.96E+08 4.85E+08 - - - 6.3469 0.997 221125_WJC_METTL3_EV_vs_WT_F08.20503.20503.4 0.00398 9/120 K.NLPQDSNC[160.03]QEVHDLLKDYDLK.Y sp|Q9HCJ3|RAVR2_HUMAN 1 2543.1962 2.83 121958 20503 4 2543.208863 636.8063 Ribonucleoprotein PTB-binding 2 OS=Homo sapiens OX=9606 GN=RAVER2 PE=1 SV=2 4.35 3371.6 - 219032 - - - 4.9725 - 1.776 0.475 - 27.3 1 2 1 0.0126 21 0 0 0 7.91E+06 2.79E+06 - - - 3.5468 1 221125_WJC_METTL3_EV_vs_WT_F08.20507.20507.4 1.89E-11 18/96 R.DLIGHIVEFSQDQHGSR.F "sp|Q8TB72|PUM2_HUMAN,tr|A0A0C4DG68|A0A0C4DG68_HUMAN" 2 1936.9391 1.43 121960 20507 4 1936.943082 485.2421 Pumilio homolog 2 OS=Homo sapiens OX=9606 GN=PUM2 PE=1 SV=2 5.21 3372.2 - 243959 - - - 2.0362 - 3.37 0.657 - 188 1 2 0 0.0039 17 0 0 0 2.51E+07 1.76E+07 - - - 5.3652 0.9999 221125_WJC_METTL3_EV_vs_WT_F08.20508.20508.3 4.13E-05 Sep-92 K.SQGLSQLYHNQSQGLLSQLQGQSK[136.11].D "sp|P78344|IF4G2_HUMAN,tr|D3DQV9|D3DQV9_HUMAN" 2 2636.3398 2.06 121961 20508 3 2636.345247 879.7872 Eukaryotic translation initiation factor 4 gamma 2 OS=Homo sapiens OX=9606 GN=EIF4G2 PE=1 SV=1 8.33 3372.3 - 306678 - - - 2.0692 - 2.283 0.473 - 73.5 1 2 0 0.0055 24 0 0 0 9.96E+08 4.85E+08 - - - 5.7293 0.9998 221125_WJC_METTL3_EV_vs_WT_F08.20512.20512.3 1.57E-07 13/56 R.STSHK[136.11]PDEIYGMIER[166.11].L sp|Q86U44|MTA70_HUMAN 1 1779.8581 0.88 121962 20512 3 1779.864869 594.2933 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 5.42 3373.1 - 209988 - - - 3.829 - 2.411 0.509 - 223.5 1 2 0 0.0068 15 0 0 0 1.45E+07 1.65E+07 - - - 6.5093 1 221125_WJC_METTL3_EV_vs_WT_F08.20513.20513.3 1.34E-08 15/128 R.SDSPVPTAPTSGGPK[136.11]PSTASAVPELATDPELEK[136.11].K "sp|Q86U44|MTA70_HUMAN,tr|B4E349|B4E349_HUMAN,tr|F5H6D8|F5H6D8_HUMAN,tr|B4DTN4|B4DTN4_HUMAN" 4 3248.6271 0.02 121963 20513 3 3248.630849 1083.883 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 4.18 3373.2 - 239904 - - - 1.1546 - 2.903 0.542 - 97.6 1 2 0 0.0037 33 0 0 0 3.54E+05 2.29E+07 - - - 7.0336 1 221125_WJC_METTL3_EV_vs_WT_F08.20514.20514.3 1.65E-12 24/64 R.DLIGHIVEFSQDQHGSR[166.11].F "sp|Q8TB72|PUM2_HUMAN,tr|A0A0C4DG68|A0A0C4DG68_HUMAN" 2 1946.9474 1.41 121964 20514 3 1946.954074 649.9897 Pumilio homolog 2 OS=Homo sapiens OX=9606 GN=PUM2 PE=1 SV=2 5.21 3373.3 - 560306 - - - 3.4238 - 4.237 0.68 - 787 1 2 0 0.0067 17 0 0 0 7.36E+07 5.24E+07 - - - 9.7671 0.9788 221125_WJC_METTL3_EV_vs_WT_F08.20523.20523.4 0.0756 7/186 K.VGGTNLGAPGAFGQSPFSQPPAPPHQNTFPPR.S sp|Q96I24|FUBP3_HUMAN 1 3227.5901 3.48 121968 20523 4 3227.607881 807.9048 Far upstream element-binding protein 3 OS=Homo sapiens OX=9606 GN=FUBP3 PE=1 SV=2 9.73 3374.6 - 124311 - - - 5.5153 - 1.665 0.302 - 15.6 1 2 0 0.0178 32 0 0 0 3.66E+06 1.05E+06 - - - 2.0036 1 221125_WJC_METTL3_EV_vs_WT_F08.20525.20525.3 4.47E-09 26/64 R.HGVQELEIELQSQLSKK.A "sp|P35527|K1C9_HUMAN,tr|K7EQQ3|K7EQQ3_HUMAN" 2 1965.0531 1042.38 121969 20525 3 1965.061382 656.025 "Keratin, type I cytoskeletal 9 OS=Homo sapiens OX=9606 GN=KRT9 PE=1 SV=3" 5.5 3374.8 - 700588 - - - 4.2121 - 4.849 0.606 - 1085 1 2 0 0.0083 17 0 0 0 3.76E+07 3.61E+04 - - - 9.2825 1 221125_WJC_METTL3_EV_vs_WT_F08.20527.20527.4 2.05E-14 29/162 K.DR[166.11]PQEADGIDSVIVVDNVPQVGPDR[166.11]LEK[136.11].L "sp|P55884|EIF3B_HUMAN,tr|C9JZG1|C9JZG1_HUMAN" 2 3087.5831 1.22 121970 20527 4 3087.572239 772.9031 Eukaryotic translation initiation factor 3 subunit B OS=Homo sapiens OX=9606 GN=EIF3B PE=1 SV=3 4.09 3375 - 1.18E+06 - - - -3.5167 - 5.216 0.637 - 407.7 1 2 1 -0.0109 28 0 0 0 7.38E+07 6.04E+07 - - - 5.2803 0.9999 221125_WJC_METTL3_EV_vs_WT_F08.20529.20529.4 3.34E-10 17/102 R.SPSELFAQHIVTIVHHVK.E "sp|Q9Y2W1|TR150_HUMAN,tr|A0A3B3ITZ9|A0A3B3ITZ9_HUMAN" 2 2041.1109 2.77 121971 20529 4 2041.1182 511.285 Thyroid hormone receptor-associated protein 3 OS=Homo sapiens OX=9606 GN=THRAP3 PE=1 SV=2 6.78 3375.2 - 648836 - - - 3.5789 - 3.4 0.579 - 216.9 1 2 0 0.0073 18 0 0 0 1.04E+09 3.74E+08 - - - 4.6828 1 221125_WJC_METTL3_EV_vs_WT_F08.20530.20530.3 5.33E-09 11/108 K.DRPQEADGIDSVIVVDNVPQVGPDRLEK.L "sp|P55884|EIF3B_HUMAN,tr|C9JZG1|C9JZG1_HUMAN" 2 3059.5524 2.47 121972 20530 3 3059.557902 1020.8581 Eukaryotic translation initiation factor 3 subunit B OS=Homo sapiens OX=9606 GN=EIF3B PE=1 SV=3 4.09 3375.4 - 111815 - - - 1.8124 - 3.412 0.676 - 56.7 1 2 1 0.0055 28 0 0 0 4.37E+06 1.77E+06 - - - 8.8988 0.9971 221125_WJC_METTL3_EV_vs_WT_F08.20541.20541.4 4.77E-06 12/138 K.SQGLSQLYHNQSQGLLSQLQGQSK.D "sp|P78344|IF4G2_HUMAN,tr|D3DQV9|D3DQV9_HUMAN" 2 2628.3256 2.27 121978 20541 4 2628.339443 658.0887 Eukaryotic translation initiation factor 4 gamma 2 OS=Homo sapiens OX=9606 GN=EIF4G2 PE=1 SV=1 8.33 3376.8 - 398595 - - - 5.2699 - 2.488 0.385 - 73.7 1 2 0 0.0139 24 0 0 0 3.85E+07 1.70E+07 - - - 2.8658 1 221125_WJC_METTL3_EV_vs_WT_F08.20542.20542.4 7.84E-06 19/168 K.VSNTQYHEVMNLEPENTLDQHSFSLPTC[160.03]R[166.11].L sp|O43264|ZW10_HUMAN 1 3455.575 1.15 121979 20542 4 3455.579117 864.901 Centromere\kinetochore protein zw10 homolog OS=Homo sapiens OX=9606 GN=ZW10 PE=1 SV=3 4.8 3376.9 - 387866 - - - 1.1989 - 3.765 0.538 - 125.2 1 2 0 0.0041 29 0 0 0 6.09E+06 5.31E+06 - - - 4.3162 0.9999 221125_WJC_METTL3_EV_vs_WT_F08.20552.20552.4 8.91E-05 11/138 K.SQGLSQLYHNQSQGLLSQLQGQSK[136.11].D "sp|P78344|IF4G2_HUMAN,tr|D3DQV9|D3DQV9_HUMAN" 2 2636.3398 2.27 121983 20552 4 2636.338507 660.0922 Eukaryotic translation initiation factor 4 gamma 2 OS=Homo sapiens OX=9606 GN=EIF4G2 PE=1 SV=1 8.33 3378.4 - 697614 - - - -0.4874 - 2.536 0.435 - 73.1 1 2 0 -0.0013 24 0 0 0 3.85E+07 1.70E+07 - - - 3.3106 1 221125_WJC_METTL3_EV_vs_WT_F08.20557.20557.4 1.71E-07 15/180 R.YQDEDTPPQEHISPQITNEVIGPELVHVSEK.N "sp|Q12959|DLG1_HUMAN,tr|A0A590UJZ4|A0A590UJZ4_HUMAN,tr|A0A590UJ18|A0A590UJ18_HUMAN,tr|A0A590UKA8|A0A590UKA8_HUMAN,tr|B4E2H8|B4E2H8_HUMAN,tr|A0A590UK13|A0A590UK13_HUMAN,tr|A0A0C4DFT3|A0A0C4DFT3_HUMAN,tr|A0A590UJD9|A0A590UJD9_HUMAN,tr|A0A590UJ95|A0A590UJ95_HUMAN,tr|A0A590UJL2|A0A590UJL2_HUMAN,tr|A8MUT6|A8MUT6_HUMAN,tr|A0A590UJ08|A0A590UJ08_HUMAN,tr|C9JUA9|C9JUA9_HUMAN,tr|C9JN61|C9JN61_HUMAN,tr|A0A590UJ68|A0A590UJ68_HUMAN,tr|A0A590UK81|A0A590UK81_HUMAN,tr|C9JCP6|C9JCP6_HUMAN,tr|E7EQD7|E7EQD7_HUMAN,tr|A0A590UK52|A0A590UK52_HUMAN,tr|A0A590UJ81|A0A590UJ81_HUMAN,tr|A0A590UJ86|A0A590UJ86_HUMAN,tr|A0A590UJC5|A0A590UJC5_HUMAN,tr|A0A590UK02|A0A590UK02_HUMAN,tr|A0A590UJ64|A0A590UJ64_HUMAN,tr|A0A590UJ29|A0A590UJ29_HUMAN,tr|A0A590UJS9|A0A590UJS9_HUMAN,tr|A0A590UJR5|A0A590UJR5_HUMAN,tr|C9IYP1|C9IYP1_HUMAN" 28 3527.7056 2.64 121985 20557 4 3527.703116 882.9337 Disks large homolog 1 OS=Homo sapiens OX=9606 GN=DLG1 PE=1 SV=2 4.24 3379.1 - 292064 - - - -0.7107 - 2.664 0.572 - 103.4 1 2 0 -0.0025 31 0 0 0 9.14E+06 3.47E+06 - - - 4.5018 0.9982 221125_WJC_METTL3_EV_vs_WT_F08.20587.20587.4 0.00603 Oct-96 K.EKPKPTPDYLMQLMNDK.K sp|Q96PU8|QKI_HUMAN 1 2047.0118 3.05 122001 20587 4 2047.013017 512.7602 Protein quaking OS=Homo sapiens OX=9606 GN=QKI PE=1 SV=1 6.22 3383.1 - 370418 - - - 0.5779 - 1.817 0.273 - 72.5 1 2 0 0.0012 17 0 0 0 9.34E+06 3.07E+06 - - - 1.8092 1 221125_WJC_METTL3_EV_vs_WT_F08.20599.20599.4 1.41E-09 31/138 K.KGADSLEDFLYHEGYAC[160.03]TSIHGDR.S "sp|O00571|DDX3X_HUMAN,sp|O15523|DDX3Y_HUMAN,tr|A0A2R8YFR4|A0A2R8YFR4_HUMAN,tr|A0A2R8YCW1|A0A2R8YCW1_HUMAN,tr|A0A2R8YDH3|A0A2R8YDH3_HUMAN,tr|A0A2R8YDT5|A0A2R8YDT5_HUMAN,tr|A0A2R8Y645|A0A2R8Y645_HUMAN,tr|A0A2R8YF78|A0A2R8YF78_HUMAN,tr|A0A0D9SFB3|A0A0D9SFB3_HUMAN,tr|A0A2R8YFS5|A0A2R8YFS5_HUMAN,tr|A0A0D9SF53|A0A0D9SF53_HUMAN,tr|A0A0J9YVQ7|A0A0J9YVQ7_HUMAN,tr|A0A2R8Y5G6|A0A2R8Y5G6_HUMAN,tr|A0A2R8Y7T2|A0A2R8Y7T2_HUMAN,tr|A0A0D9SG12|A0A0D9SG12_HUMAN,tr|F6S8Q4|F6S8Q4_HUMAN,tr|A0A2U3TZJ9|A0A2U3TZJ9_HUMAN,tr|A0A2R8Y4A4|A0A2R8Y4A4_HUMAN" 18 2740.2187 1.18 122008 20599 4 2740.223588 686.062 ATP-dependent RNA helicase DDX3X OS=Homo sapiens OX=9606 GN=DDX3X PE=1 SV=3 4.8 3384.6 - 459519 - - - 1.7677 - 5.737 0.71 - 777.9 1 2 0 0.0048 24 0 0 0 1.06E+07 9.03E+06 - - - 5.9652 1 221125_WJC_METTL3_EV_vs_WT_F08.20606.20606.3 9.15E-06 15/68 R.DVQIGDIVTVGEC[160.03]R[166.11]PLSK[136.11].T "sp|P62280|RS11_HUMAN,tr|M0R1H5|M0R1H5_HUMAN" 2 2003.0476 1.04 122011 20606 3 2003.042467 668.6898 40S ribosomal protein S11 OS=Homo sapiens OX=9606 GN=RPS11 PE=1 SV=3 4.56 3385.5 - 282117 - - - -2.5856 - 2.972 0.564 - 225.4 1 2 0 -0.0052 18 0 0 0 6.56E+06 6.32E+06 - - - 7.5389 0.9956 221125_WJC_METTL3_EV_vs_WT_F08.20609.20609.3 5.19E-06 Nov-76 L.AISTPDAPATQDGVESLLQK[136.11].F "sp|Q86U44|MTA70_HUMAN,tr|B4E349|B4E349_HUMAN,tr|F5H6D8|F5H6D8_HUMAN,tr|H0YFV6|H0YFV6_HUMAN,tr|B4DTN4|B4DTN4_HUMAN" 5 2048.0517 1.44 122012 20609 3 2048.050258 683.6912 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 4.03 3385.9 - 528462 - - - -0.7114 - 2.375 0.489 - 109.2 1 1 0 -0.0015 20 0 0 0 1.81E+07 1.26E+07 - - - 6.09 1 221125_WJC_METTL3_EV_vs_WT_F08.20611.20611.4 2.48E-12 26/144 K.AQQIHSQTSQQYPLYDLDLGKFGEK.V sp|P15924|DESP_HUMAN 1 2893.4246 22.84 122013 20611 4 2893.434942 724.3634 Desmoplakin OS=Homo sapiens OX=9606 GN=DSP PE=1 SV=3 5.38 3386.2 - 511405 - - - 3.5615 - 4.811 0.621 - 507.7 1 2 1 0.0103 25 0 0 0 1.99E+07 8.72E+05 - - - 5.1281 0.9999 221125_WJC_METTL3_EV_vs_WT_F08.20613.20613.4 9.77E-09 17/144 K.NNKNEFVSLINC[160.03]SSQPPLISHGIGK.D "sp|O95793|STAU1_HUMAN,tr|Q5JW30|Q5JW30_HUMAN" 2 2752.3966 1.96 122015 20613 4 2752.397941 689.1064 Double-stranded RNA-binding protein Staufen homolog 1 OS=Homo sapiens OX=9606 GN=STAU1 PE=1 SV=2 8.21 3386.4 - 765728 - - - 0.4694 - 3.577 0.6 - 93 1 2 1 0.0013 25 0 0 0 1.76E+08 8.97E+07 - - - 4.8535 1 221125_WJC_METTL3_EV_vs_WT_F08.20623.20623.4 7.45E-09 21/150 R.EGHPVYPQLR[166.11]PGYIPIPVLHEGAENR[166.11].Q "sp|O95817|BAG3_HUMAN,tr|C9JFK9|C9JFK9_HUMAN" 2 2957.5415 0.37 122022 20623 4 2957.559364 740.3927 BAG family molecular chaperone regulator 3 OS=Homo sapiens OX=9606 GN=BAG3 PE=1 SV=3 6.03 3387.7 - 432635 - - - 6.0402 - 3.974 0.624 - 240.6 1 2 0 0.0179 26 0 0 0 4.56E+06 1.25E+07 - - - 5.0876 0.9967 221125_WJC_METTL3_EV_vs_WT_F08.20627.20627.4 2.19E-06 13/138 H.SSC[160.03]HIC[160.03]TAADDHQALIWDIQQMPR.A sp|P61962|DCAF7_HUMAN 1 2852.2793 4.72 122024 20627 4 2852.279072 714.0771 DDB1- and CUL4-associated factor 7 OS=Homo sapiens OX=9606 GN=DCAF7 PE=1 SV=1 5.12 3388.2 - 334514 - - - -0.0635 - 2.53 0.529 - 118.3 1 1 0 -0.0002 24 0 0 0 4.56E+06 9.64E+05 - - - 4.1283 1 221125_WJC_METTL3_EV_vs_WT_F08.20638.20638.4 2.61E-16 38/216 K.RPSYAPPPTPAPATQMPSTPGFVGYNPYSHLAYNNYR.L "sp|Q969G3|SMCE1_HUMAN,tr|A0A2R8Y855|A0A2R8Y855_HUMAN,tr|J3QL66|J3QL66_HUMAN,tr|J3QKX6|J3QKX6_HUMAN,tr|A0A2R8YDQ4|A0A2R8YDQ4_HUMAN" 5 4078.9425 3.28 122032 20638 4 4078.945728 1020.7429 SWI\SNF-related matrix-associated actin-dependent regulator of chromatin subfamily E member 1 OS=Homo sapiens OX=9606 GN=SMARCE1 PE=1 SV=2 9.4 3389.6 - 579364 - - - 0.8022 - 5.014 0.707 - 656.2 1 2 0 0.0033 37 0 0 0 1.62E+07 4.93E+06 - - - 5.8515 1 221125_WJC_METTL3_EV_vs_WT_F08.20639.20639.3 8.18E-21 26/116 K.TAQQNGDTPEAQGLDITTYGESNLVAEPQK.V "sp|Q15003|CND2_HUMAN,tr|E9PHA2|E9PHA2_HUMAN,tr|H7C415|H7C415_HUMAN" 3 3174.4953 1.61 122033 20639 3 3174.500645 1059.1724 Condensin complex subunit 2 OS=Homo sapiens OX=9606 GN=NCAPH PE=1 SV=3 3.83 3389.7 - 480696 - - - 1.685 - 4.69 0.794 - 444.7 1 2 0 0.0053 30 0 0 0 1.52E+07 9.47E+06 - - - 10.9463 1 221125_WJC_METTL3_EV_vs_WT_F08.20644.20644.3 1.94E-08 Oct-52 K.K[136.11]GPGEVAGTVTGQK[136.11].R "sp|Q86U44|MTA70_HUMAN,tr|F5H6D8|F5H6D8_HUMAN,tr|H0YFV6|H0YFV6_HUMAN,tr|B4DTN4|B4DTN4_HUMAN" 4 1343.738 0.001 122036 20644 3 1343.740409 448.9199 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 8.59 3390.3 - 157490 - - - 1.8084 - 2.348 0.61 - 167.5 1 2 0 0.0024 14 0 0 0 0.00E+00 3.21E+06 - - - 7.6086 1 221125_WJC_METTL3_EV_vs_WT_F08.20646.20646.3 3.63E-06 Dec-72 R.MDSFDEDLARPSGLLAQER.K "sp|Q9Y2W1|TR150_HUMAN,tr|A0A3B3ITZ9|A0A3B3ITZ9_HUMAN" 2 2149.011 3.37 122038 20646 3 2149.012592 717.3443 Thyroid hormone receptor-associated protein 3 OS=Homo sapiens OX=9606 GN=THRAP3 PE=1 SV=2 4.1 3390.6 - 875527 - - - 0.7487 - 2.653 0.549 - 154.3 1 2 0 0.0016 19 0 0 0 4.27E+07 1.27E+07 - - - 7.0574 1 221125_WJC_METTL3_EV_vs_WT_F08.20647.20647.3 1.62E-12 22/96 K.NNKNEFVSLINC[160.03]SSQPPLISHGIGK.D "sp|O95793|STAU1_HUMAN,tr|Q5JW30|Q5JW30_HUMAN" 2 2752.3966 1.82 122039 20647 3 2752.395374 918.4728 Double-stranded RNA-binding protein Staufen homolog 1 OS=Homo sapiens OX=9606 GN=STAU1 PE=1 SV=2 8.21 3390.7 - 503268 - - - -0.4632 - 4.245 0.719 - 361.4 1 2 1 -0.0013 25 0 0 0 2.06E+07 1.14E+07 - - - 9.8819 0.9992 221125_WJC_METTL3_EV_vs_WT_F08.20655.20655.3 3.84E-10 21/100 K.DK[136.11]NFQWANTGAAVFGTQSVGTQSAGK[136.11].V sp|P49792|RBP2_HUMAN 1 2685.3118 1.24 122043 20655 3 2685.324774 896.1112 E3 SUMO-protein ligase RanBP2 OS=Homo sapiens OX=9606 GN=RANBP2 PE=1 SV=2 8.59 3391.8 - 666462 - - - 4.8341 - 3.329 0.6 - 405.9 1 2 1 0.013 26 0 0 0 9.81E+06 7.91E+06 - - - 7.9927 0.9999 221125_WJC_METTL3_EV_vs_WT_F08.20658.20658.3 1.66E-08 14/96 K.NNK[136.11]NEFVSLINC[160.03]SSQPPLISHGIGK[136.11].D "sp|O95793|STAU1_HUMAN,tr|Q5JW30|Q5JW30_HUMAN" 2 2768.425 1.82 122044 20658 3 2768.426872 923.8156 Double-stranded RNA-binding protein Staufen homolog 1 OS=Homo sapiens OX=9606 GN=STAU1 PE=1 SV=2 8.21 3392.2 - 506314 - - - 0.6585 - 2.779 0.618 - 111.9 1 2 1 0.0018 25 0 0 0 2.06E+07 1.14E+07 - - - 7.781 1 221125_WJC_METTL3_EV_vs_WT_F08.20663.20663.4 5.16E-08 25/138 R.HAMNLEAVNTYEGTHDIHALILGR.A sp|Q92947|GCDH_HUMAN 1 2674.3286 1.04 122047 20663 4 2674.33232 669.5894 "Glutaryl-CoA dehydrogenase, mitochondrial OS=Homo sapiens OX=9606 GN=GCDH PE=1 SV=1" 5.75 3393 - 354246 - - - 1.4026 - 5.351 0.71 - 619.3 1 2 0 0.0038 24 0 0 0 1.13E+07 1.08E+07 - - - 5.9432 1 221125_WJC_METTL3_EV_vs_WT_F08.20685.20685.3 2.60E-08 16/68 K.TVTNAVVTVPAYFNDSQR[166.11].Q "sp|P11142|HSP7C_HUMAN,tr|E9PQQ4|E9PQQ4_HUMAN,tr|E9PN89|E9PN89_HUMAN,tr|E9PLF4|E9PLF4_HUMAN,tr|E9PI65|E9PI65_HUMAN,tr|E9PK54|E9PK54_HUMAN,tr|E9PQK7|E9PQK7_HUMAN" 7 1990.9988 0.12 122060 20685 3 1991.003504 664.6735 Heat shock cognate 71 kDa protein OS=Homo sapiens OX=9606 GN=HSPA8 PE=1 SV=1 5.5 3395.9 - 619416 - - - 2.3752 - 3.001 0.562 - 350.9 1 2 0 0.0047 18 0 0 0 3.30E+06 2.76E+07 - - - 7.5409 0.9999 221125_WJC_METTL3_EV_vs_WT_F08.20689.20689.4 7.02E-14 27/144 K.NNK[136.11]NEFVSLINC[160.03]SSQPPLISHGIGK[136.11].D "sp|O95793|STAU1_HUMAN,tr|Q5JW30|Q5JW30_HUMAN" 2 2768.425 1.96 122063 20689 4 2768.426003 693.1135 Double-stranded RNA-binding protein Staufen homolog 1 OS=Homo sapiens OX=9606 GN=STAU1 PE=1 SV=2 8.21 3396.4 - 1.56E+06 - - - 0.3446 - 3.897 0.606 - 336.4 1 2 1 0.001 25 0 0 0 1.75E+08 8.93E+07 - - - 4.9331 1 221125_WJC_METTL3_EV_vs_WT_F08.20692.20692.3 1.89E-16 24/136 K.GEGAPGQPAEDSVKQEGLDLTGTAATATSFAAPPK.V "sp|Q8IVH2|FOXP4_HUMAN,tr|A0A590UJX7|A0A590UJX7_HUMAN,tr|B7ZBM3|B7ZBM3_HUMAN" 3 3368.6372 6.27 122065 20692 3 3368.639728 1123.8863 Forkhead box protein P4 OS=Homo sapiens OX=9606 GN=FOXP4 PE=1 SV=1 4.18 3396.8 - 663632 - - - 0.7478 - 4.154 0.743 - 300.6 1 2 1 0.0025 35 0 0 0 2.06E+07 3.29E+06 - - - 10.0993 0.9998 221125_WJC_METTL3_EV_vs_WT_F08.20693.20693.4 2.55E-05 15/204 K.GEGAPGQPAEDSVKQEGLDLTGTAATATSFAAPPK.V "sp|Q8IVH2|FOXP4_HUMAN,tr|A0A590UJX7|A0A590UJX7_HUMAN,tr|B7ZBM3|B7ZBM3_HUMAN" 3 3368.6372 10.02 122066 20693 4 3368.632623 843.1666 Forkhead box protein P4 OS=Homo sapiens OX=9606 GN=FOXP4 PE=1 SV=1 4.18 3396.9 - 593989 - - - -1.3614 - 3.089 0.477 - 72.3 1 2 1 -0.0046 35 0 0 0 1.41E+07 1.41E+06 - - - 3.7109 0.9999 221125_WJC_METTL3_EV_vs_WT_F08.20694.20694.3 8.77E-09 Dec-44 R.AR[166.11]FEELC[160.03]SDLFR[166.11].S "sp|P48741|HSP77_HUMAN,sp|P0DMV8|HS71A_HUMAN,sp|P0DMV9|HS71B_HUMAN,sp|P17066|HSP76_HUMAN,tr|V9GZ37|V9GZ37_HUMAN,tr|A0A0G2JIW1|A0A0G2JIW1_HUMAN" 6 1561.7462 0.17 122067 20694 3 1561.745641 521.5893 Putative heat shock 70 kDa protein 7 OS=Homo sapiens OX=9606 GN=HSPA7 PE=5 SV=2 4.68 3397 - 438430 - - - -0.3599 - 2.58 0.565 - 271.8 1 2 1 -0.0006 12 0 0 0 1.67E+06 9.59E+06 - - - 7.4662 0.9999 221125_WJC_METTL3_EV_vs_WT_F08.20698.20698.3 3.97E-05 14/60 K.KDC[160.03]EVVMMIGLPGAGK.T "sp|Q00839|HNRPU_HUMAN,tr|A0A1W2PQL0|A0A1W2PQL0_HUMAN,tr|A0A1W2PPL4|A0A1W2PPL4_HUMAN,tr|A0A1W2PQ74|A0A1W2PQ74_HUMAN,tr|Q5RI18|Q5RI18_HUMAN,tr|A0A1W2PP35|A0A1W2PP35_HUMAN,tr|A0A1W2PPS1|A0A1W2PPS1_HUMAN,tr|A0A1W2PRZ7|A0A1W2PRZ7_HUMAN,tr|A0A1W2PPH7|A0A1W2PPH7_HUMAN,tr|A0A1W2PQD4|A0A1W2PQD4_HUMAN,tr|A0A1W2PP34|A0A1W2PP34_HUMAN,tr|A0A1X7SBS1|A0A1X7SBS1_HUMAN" 12 1703.8409 0.54 122069 20698 3 1703.846077 568.9542 Heterogeneous nuclear ribonucleoprotein U OS=Homo sapiens OX=9606 GN=HNRNPU PE=1 SV=6 6.06 3397.6 - 262638 - - - 3.056 - 2.682 0.559 - 221 1 2 0 0.0052 16 0 0 0 5.59E+06 1.03E+07 - - - 7.3022 0.9999 221125_WJC_METTL3_EV_vs_WT_F08.20706.20706.3 8.96E-07 16/136 K.GEGAPGQPAEDSVK[136.11]QEGLDLTGTAATATSFAAPPK[136.11].V "sp|Q8IVH2|FOXP4_HUMAN,tr|A0A590UJX7|A0A590UJX7_HUMAN,tr|B7ZBM3|B7ZBM3_HUMAN" 3 3384.6656 6.24 122075 20706 3 3384.670828 1129.2291 Forkhead box protein P4 OS=Homo sapiens OX=9606 GN=FOXP4 PE=1 SV=1 4.18 3398.6 - 374279 - - - 1.542 - 2.974 0.558 - 111.7 1 2 1 0.0052 35 0 0 0 2.05E+07 3.29E+06 - - - 7.2672 0.9951 221125_WJC_METTL3_EV_vs_WT_F08.20711.20711.4 0.000147 19/108 K.ISSIQSIVPALEIANAHR[166.11]K[136.11].P "sp|P10809|CH60_HUMAN,tr|A0A7I2V2X6|A0A7I2V2X6_HUMAN,tr|A0A7I2YQK6|A0A7I2YQK6_HUMAN,tr|A0A7I2V599|A0A7I2V599_HUMAN,tr|A0A7I2YQ71|A0A7I2YQ71_HUMAN,tr|A0A7I2V5M1|A0A7I2V5M1_HUMAN,tr|A0A7I2V5K3|A0A7I2V5K3_HUMAN,tr|A0A7I2V369|A0A7I2V369_HUMAN" 8 2064.181 0.88 122078 20711 4 2064.183518 517.0525 "60 kDa heat shock protein, mitochondrial OS=Homo sapiens OX=9606 GN=HSPD1 PE=1 SV=2" 8.75 3399.3 - 275998 - - - 1.199 - 2.931 0.483 - 324.4 1 1 0 0.0025 19 0 0 0 1.71E+07 1.95E+07 - - - 3.7931 0.8748 221125_WJC_METTL3_EV_vs_WT_F08.20714.20714.4 1.37E-06 18/108 K.ISSIQSIVPALEIANAHRK.P "sp|P10809|CH60_HUMAN,tr|A0A7I2V2X6|A0A7I2V2X6_HUMAN,tr|A0A7I2YQK6|A0A7I2YQK6_HUMAN,tr|A0A7I2V599|A0A7I2V599_HUMAN,tr|A0A7I2YQ71|A0A7I2YQ71_HUMAN,tr|A0A7I2V5M1|A0A7I2V5M1_HUMAN,tr|A0A7I2V5K3|A0A7I2V5K3_HUMAN,tr|A0A7I2V369|A0A7I2V369_HUMAN" 8 2046.1586 0.85 122081 20714 4 2046.163862 512.5469 "60 kDa heat shock protein, mitochondrial OS=Homo sapiens OX=9606 GN=HSPD1 PE=1 SV=2" 8.75 3399.7 - 352279 - - - 2.5848 - 3.243 0.313 - 249.4 1 1 0 0.0053 19 0 0 0 1.46E+07 1.72E+07 - - - 2.3469 0.9999 221125_WJC_METTL3_EV_vs_WT_F08.20718.20718.3 1.66E-05 13/60 K.K[136.11]DC[160.03]EVVMMIGLPGAGK[136.11].T "sp|Q00839|HNRPU_HUMAN,tr|A0A1W2PQL0|A0A1W2PQL0_HUMAN,tr|A0A1W2PPL4|A0A1W2PPL4_HUMAN,tr|A0A1W2PQ74|A0A1W2PQ74_HUMAN,tr|Q5RI18|Q5RI18_HUMAN,tr|A0A1W2PP35|A0A1W2PP35_HUMAN,tr|A0A1W2PPS1|A0A1W2PPS1_HUMAN,tr|A0A1W2PRZ7|A0A1W2PRZ7_HUMAN,tr|A0A1W2PPH7|A0A1W2PPH7_HUMAN,tr|A0A1W2PQD4|A0A1W2PQD4_HUMAN,tr|A0A1W2PP34|A0A1W2PP34_HUMAN,tr|A0A1X7SBS1|A0A1X7SBS1_HUMAN" 12 1719.8693 0.54 122083 20718 3 1719.872538 574.297 Heterogeneous nuclear ribonucleoprotein U OS=Homo sapiens OX=9606 GN=HNRNPU PE=1 SV=6 6.06 3400.2 - 288762 - - - 1.9001 - 2.322 0.529 - 135.5 1 2 0 0.0033 16 0 0 0 5.64E+06 1.05E+07 - - - 6.5985 0.9998 221125_WJC_METTL3_EV_vs_WT_F08.20720.20720.2 0.0019 16-Oct R.YLDVSILGK[136.11].F sp|Q86U44|MTA70_HUMAN 1 1014.5841 0.02 122085 20720 2 1014.585424 508.2993 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 5.83 3400.5 - 195555 - - - 1.3069 - 2.022 0.486 - 246.9 1 2 0 0.0013 9 0 0 0 3.73E+06 2.10E+08 - - - 4.6671 0.9996 221125_WJC_METTL3_EV_vs_WT_F08.20738.20738.4 6.20E-05 12/150 K.QLPDKWQHDLFDSGFGGGAGVETGGK.L "sp|Q86V81|THOC4_HUMAN,tr|E9PB61|E9PB61_HUMAN" 2 2702.2725 0.72 122096 20738 4 2702.279315 676.5754 THO complex subunit 4 OS=Homo sapiens OX=9606 GN=ALYREF PE=1 SV=3 4.66 3402.7 - 496393 - - - 2.5242 - 2.351 0.479 - 81.8 1 2 1 0.0068 26 0 0 0 1.89E+08 2.64E+08 - - - 3.663 0.9995 221125_WJC_METTL3_EV_vs_WT_F08.20742.20742.2 1.17E-05 Oct-34 K.TVTNAVVTVPAYFNDSQR[166.11].Q "sp|P11142|HSP7C_HUMAN,tr|E9PQQ4|E9PQQ4_HUMAN,tr|E9PN89|E9PN89_HUMAN,tr|E9PLF4|E9PLF4_HUMAN,tr|E9PI65|E9PI65_HUMAN,tr|E9PK54|E9PK54_HUMAN,tr|E9PQK7|E9PQK7_HUMAN" 7 1990.9988 0.01 122098 20742 2 1991.003574 996.5067 Heat shock cognate 71 kDa protein OS=Homo sapiens OX=9606 GN=HSPA8 PE=1 SV=1 5.5 3403.3 - 154730 - - - 2.4103 - 1.967 0.482 - 190.6 1 2 0 0.0048 18 0 0 0 6.39E+04 4.94E+06 - - - 4.2628 1 221125_WJC_METTL3_EV_vs_WT_F08.20745.20745.3 3.27E-08 13/56 R.STSHK[136.11]PDEIYGMIER[166.11].L sp|Q86U44|MTA70_HUMAN 1 1779.8581 0.05 122101 20745 3 1779.858766 594.2933 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 5.42 3403.7 - 259982 - - - 0.4 - 2.501 0.554 - 213.3 1 2 0 0.0007 15 0 0 0 1.17E+06 2.37E+07 - - - 7.1083 1 221125_WJC_METTL3_EV_vs_WT_F08.20751.20751.4 8.29E-11 20/126 K.HTDESLGDC[160.03]SFLNTC[160.03]FHMDTC[160.03]K[136.11].Y "sp|Q86U44|MTA70_HUMAN,tr|H0YFV6|H0YFV6_HUMAN" 2 2682.0698 0.37 122103 20751 4 2682.072549 671.5247 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 4.64 3404.6 - 352944 - - - 1.0085 - 3.99 0.703 - 301.7 1 2 0 0.0027 22 0 0 0 2.44E+06 6.66E+06 - - - 5.7969 0.9999 221125_WJC_METTL3_EV_vs_WT_F08.20756.20756.3 2.36E-07 13/100 K.QLPDK[136.11]WQHDLFDSGFGGGAGVETGGK[136.11].L "sp|Q86V81|THOC4_HUMAN,tr|E9PB61|E9PB61_HUMAN" 2 2718.3009 0.69 122104 20756 3 2718.302994 907.1076 THO complex subunit 4 OS=Homo sapiens OX=9606 GN=ALYREF PE=1 SV=3 4.66 3405.3 - 239617 - - - 0.7725 - 2.73 0.595 - 108.9 1 2 1 0.0021 26 0 0 0 3.09E+07 4.48E+07 - - - 7.4836 0.9999 221125_WJC_METTL3_EV_vs_WT_F08.20759.20759.4 0.00022 18/102 R.SPSELFAQHIVTIVHHVK.E "sp|Q9Y2W1|TR150_HUMAN,tr|A0A3B3ITZ9|A0A3B3ITZ9_HUMAN" 2 2041.1109 3.07 122106 20759 4 2041.114244 511.285 Thyroid hormone receptor-associated protein 3 OS=Homo sapiens OX=9606 GN=THRAP3 PE=1 SV=2 6.78 3405.7 - 574639 - - - 1.6408 - 2.854 0.468 - 212.9 1 2 0 0.0033 18 0 0 0 1.59E+08 5.18E+07 - - - 3.6578 0.9999 221125_WJC_METTL3_EV_vs_WT_F08.20763.20763.4 0.000522 10/162 K.AIGSSPLGSGEGLLGLSPGPNGHSHLLK[136.11].V "sp|Q8IY67|RAVR1_HUMAN,tr|K7EQG2|K7EQG2_HUMAN,tr|E9PAU2|E9PAU2_HUMAN,tr|A0A087WZ13|A0A087WZ13_HUMAN" 4 2659.4173 1.16 122108 20763 4 2659.420478 665.8616 Ribonucleoprotein PTB-binding 1 OS=Homo sapiens OX=9606 GN=RAVER1 PE=1 SV=1 6.96 3406.1 - 146773 - - - 1.1897 - 2.441 0.445 - 36.6 1 2 0 0.0032 28 0 0 0 6.96E+06 5.97E+06 - - - 3.3755 0.998 221125_WJC_METTL3_EV_vs_WT_F08.20766.20766.4 7.06E-07 21/150 K.QLPDK[136.11]WQHDLFDSGFGGGAGVETGGK[136.11].L "sp|Q86V81|THOC4_HUMAN,tr|E9PB61|E9PB61_HUMAN" 2 2718.3009 0.72 122109 20766 4 2718.300352 680.5825 THO complex subunit 4 OS=Homo sapiens OX=9606 GN=ALYREF PE=1 SV=3 4.66 3406.5 - 2.16E+06 - - - -0.1994 - 2.817 0.322 - 172.5 1 2 1 -0.0005 26 0 0 0 1.89E+08 2.64E+08 - - - 2.3552 1 221125_WJC_METTL3_EV_vs_WT_F08.20768.20768.4 3.05E-10 17/144 R.SNDLFPVHHLDNNEFC[160.03]PGDFVVDK[136.11]R[166.11].V "sp|Q9C0C9|UBE2O_HUMAN,tr|K7ES11|K7ES11_HUMAN" 2 2988.3944 1.31 122110 20768 4 2988.391902 748.1059 (E3-independent) E2 ubiquitin-conjugating enzyme OS=Homo sapiens OX=9606 GN=UBE2O PE=1 SV=3 4.72 3406.7 - 388634 - - - -0.8225 - 3.161 0.553 - 153.4 1 2 0 -0.0025 25 0 0 0 1.45E+07 1.11E+07 - - - 4.4048 0.9998 221125_WJC_METTL3_EV_vs_WT_F08.20769.20769.3 6.58E-09 13/100 K.QLPDKWQHDLFDSGFGGGAGVETGGK.L "sp|Q86V81|THOC4_HUMAN,tr|E9PB61|E9PB61_HUMAN" 2 2702.2725 0.69 122111 20769 3 2702.279967 901.7648 THO complex subunit 4 OS=Homo sapiens OX=9606 GN=ALYREF PE=1 SV=3 4.66 3406.8 - 298901 - - - 2.7655 - 2.761 0.617 - 112.7 1 2 1 0.0075 26 0 0 0 3.09E+07 4.48E+07 - - - 7.7534 1 221125_WJC_METTL3_EV_vs_WT_F08.20774.20774.4 7.21E-20 27/216 R.C[160.03]SDAAGYPHATHDLEGPPLDAYSIQGQHTISPLDLAK.L sp|Q15365|PCBP1_HUMAN 1 3944.8639 0.83 122113 20774 4 3944.865949 987.2233 Poly(rC)-binding protein 1 OS=Homo sapiens OX=9606 GN=PCBP1 PE=1 SV=2 4.7 3407.5 - 365372 - - - 0.5113 - 5.561 0.769 - 343.2 1 2 0 0.002 37 0 0 0 5.62E+07 6.79E+07 - - - 6.4218 1 221125_WJC_METTL3_EV_vs_WT_F08.20776.20776.4 3.82E-07 13/144 R.SNDLFPVHHLDNNEFC[160.03]PGDFVVDKR.V "sp|Q9C0C9|UBE2O_HUMAN,tr|K7ES11|K7ES11_HUMAN" 2 2970.3719 1.3 122115 20776 4 2970.374798 743.6002 (E3-independent) E2 ubiquitin-conjugating enzyme OS=Homo sapiens OX=9606 GN=UBE2O PE=1 SV=3 4.72 3407.7 - 395186 - - - 0.979 - 3.055 0.634 - 84.8 1 2 0 0.0029 25 0 0 0 1.45E+07 1.11E+07 - - - 5.0988 0.9926 221125_WJC_METTL3_EV_vs_WT_F08.20780.20780.2 0.147 16-Jun R.YLDVSILGK.F sp|Q86U44|MTA70_HUMAN 1 1006.5699 0.02 122116 20780 2 1006.570086 504.2922 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 5.83 3408.3 - 105650 - - - 0.1868 - 1.118 0.2 - 75.2 1 2 0 0.0002 9 0 0 0 3.73E+06 2.11E+08 - - - 0.8408 0.9965 221125_WJC_METTL3_EV_vs_WT_F08.20782.20782.3 0.000205 9/128 R.SDSPVPTAPTSGGPK[136.11]PSTASAVPELATDPELEK[136.11].K "sp|Q86U44|MTA70_HUMAN,tr|B4E349|B4E349_HUMAN,tr|F5H6D8|F5H6D8_HUMAN,tr|B4DTN4|B4DTN4_HUMAN" 4 3248.6271 0.11 122117 20782 3 3249.624532 1083.883 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 4.18 3408.5 - 445464 - - - 307.0325 - 2.207 0.482 - 33.6 1 2 0 0.9974 33 0 0 0 2.34E+06 2.16E+07 - - - 5.4588 0.9996 221125_WJC_METTL3_EV_vs_WT_F08.20787.20787.4 2.56E-05 14/162 K.AIGSSPLGSGEGLLGLSPGPNGHSHLLK.V "sp|Q8IY67|RAVR1_HUMAN,tr|K7EQG2|K7EQG2_HUMAN,tr|E9PAU2|E9PAU2_HUMAN,tr|A0A087WZ13|A0A087WZ13_HUMAN" 4 2651.4031 1.16 122119 20787 4 2651.410604 663.8581 Ribonucleoprotein PTB-binding 1 OS=Homo sapiens OX=9606 GN=RAVER1 PE=1 SV=1 6.96 3409.2 - 511106 - - - 2.8249 - 2.395 0.397 - 71.8 1 2 0 0.0075 28 0 0 0 6.96E+06 5.97E+06 - - - 2.9506 1 221125_WJC_METTL3_EV_vs_WT_F08.20794.20794.3 2.16E-09 13/56 R.GFAFVTFDDHDSVDK[136.11].L "sp|Q32P51|RA1L2_HUMAN,sp|P09651|ROA1_HUMAN,tr|A0A7I2YQX9|A0A7I2YQX9_HUMAN,tr|F8VZ49|F8VZ49_HUMAN,tr|A0A7I2V3R8|A0A7I2V3R8_HUMAN,tr|F8VTQ5|F8VTQ5_HUMAN,tr|F8W6I7|F8W6I7_HUMAN,tr|H0YH80|H0YH80_HUMAN,tr|A0A7I2V2L6|A0A7I2V2L6_HUMAN,tr|A0A7I2V3W0|A0A7I2V3W0_HUMAN,tr|A0A7I2V5U9|A0A7I2V5U9_HUMAN,tr|A0A2R8Y4L2|A0A2R8Y4L2_HUMAN" 12 1706.7668 2.13 122123 20794 3 1706.768587 569.9295 Heterogeneous nuclear ribonucleoprotein A1-like 2 OS=Homo sapiens OX=9606 GN=HNRNPA1L2 PE=2 SV=2 4.13 3410.1 - 235906 - - - 1.0669 - 2.564 0.682 - 136.6 1 2 0 0.0018 15 0 0 0 1.27E+07 5.96E+06 - - - 8.6 0.9999 221125_WJC_METTL3_EV_vs_WT_F08.20796.20796.4 3.97E-11 20/192 K.LK[136.11]TEQGGAHFSVSSLAEGSVTSVGSVNPAENFR[166.11].V sp|P13010|XRCC5_HUMAN 1 3379.6763 0.25 122124 20796 4 3379.682903 845.9264 X-ray repair cross-complementing protein 5 OS=Homo sapiens OX=9606 GN=XRCC5 PE=1 SV=3 5.5 3410.4 - 419403 - - - 1.9443 - 4.032 0.553 - 164.7 1 2 1 0.0066 33 0 0 0 2.37E+06 9.49E+06 - - - 4.4558 0.9995 221125_WJC_METTL3_EV_vs_WT_F08.20797.20797.3 6.77E-06 Oct-56 R.GFAFVTFDDHDSVDK.L "sp|Q32P51|RA1L2_HUMAN,sp|P09651|ROA1_HUMAN,tr|A0A7I2YQX9|A0A7I2YQX9_HUMAN,tr|F8VZ49|F8VZ49_HUMAN,tr|A0A7I2V3R8|A0A7I2V3R8_HUMAN,tr|F8VTQ5|F8VTQ5_HUMAN,tr|F8W6I7|F8W6I7_HUMAN,tr|H0YH80|H0YH80_HUMAN,tr|A0A7I2V2L6|A0A7I2V2L6_HUMAN,tr|A0A7I2V3W0|A0A7I2V3W0_HUMAN,tr|A0A7I2V5U9|A0A7I2V5U9_HUMAN,tr|A0A2R8Y4L2|A0A2R8Y4L2_HUMAN" 12 1698.7526 1.41 122125 20797 3 1698.7579 567.2581 Heterogeneous nuclear ribonucleoprotein A1-like 2 OS=Homo sapiens OX=9606 GN=HNRNPA1L2 PE=2 SV=2 4.13 3410.5 - 315814 - - - 3.14 - 2.051 0.409 - 56.4 1 2 0 0.0053 15 0 0 0 8.28E+06 5.87E+06 - - - 4.9728 0.9999 221125_WJC_METTL3_EV_vs_WT_F08.20804.20804.3 0.000135 13/68 R.SPSELFAQHIVTIVHHVK[136.11].E "sp|Q9Y2W1|TR150_HUMAN,tr|A0A3B3ITZ9|A0A3B3ITZ9_HUMAN" 2 2049.1251 3.02 122130 20804 3 2049.121659 684.049 Thyroid hormone receptor-associated protein 3 OS=Homo sapiens OX=9606 GN=THRAP3 PE=1 SV=2 6.78 3411.3 - 317387 - - - -1.6768 - 2.642 0.476 - 205 1 2 0 -0.0034 18 0 0 0 4.00E+07 1.32E+07 - - - 6.2652 1 221125_WJC_METTL3_EV_vs_WT_F08.20815.20815.4 3.53E-10 17/120 K.KDYSQYEENITHLQEQIVDGK.M "sp|Q9C075|K1C23_HUMAN,tr|J3QR55|J3QR55_HUMAN" 2 2536.2082 85.43 122136 20815 4 2536.209689 635.0593 "Keratin, type I cytoskeletal 23 OS=Homo sapiens OX=9606 GN=KRT23 PE=1 SV=2" 4.5 3412.8 - 656947 - - - 0.6021 - 3.941 0.677 - 227.5 1 2 0 0.0015 21 0 0 0 2.65E+07 3.10E+05 - - - 5.5716 1 221125_WJC_METTL3_EV_vs_WT_F08.20825.20825.4 7.51E-08 Dec-84 R.KNTDLYHC[160.03]LLEHLQR.L sp|Q8WVV4|POF1B_HUMAN 1 1938.9734 999 122141 20825 4 1938.974719 485.7506 Protein POF1B OS=Homo sapiens OX=9606 GN=POF1B PE=1 SV=3 6.91 3414.2 - 130507 - - - 0.6725 - 2.438 0.588 - 150.9 1 2 0 0.0013 15 0 0 0 2.56E+06 0.00E+00 - - - 4.6625 1 221125_WJC_METTL3_EV_vs_WT_F08.20832.20832.3 1.32E-09 25/112 K.ASHNNTQIQVVSASNEPLAFASC[160.03]GTEGFR.N sp|P82912|RT11_HUMAN 1 3091.4418 1 122146 20832 3 3091.444517 1031.4879 "28S ribosomal protein S11, mitochondrial OS=Homo sapiens OX=9606 GN=MRPS11 PE=1 SV=2" 5.4 3415.1 - 576740 - - - 0.8915 - 5.265 0.73 - 514.9 1 2 0 0.0028 29 0 0 0 9.76E+06 9.76E+06 - - - 10.4996 1 221125_WJC_METTL3_EV_vs_WT_F08.20843.20843.3 2.88E-08 16/92 K.YEHDDIVSTVSVLSSGTQAVSGSK.D "sp|Q9BQA1|MEP50_HUMAN,tr|H0Y711|H0Y711_HUMAN" 2 2465.1922 3.07 122151 20843 3 2465.197599 822.738 Methylosome protein 50 OS=Homo sapiens OX=9606 GN=WDR77 PE=1 SV=1 4.54 3416.7 - 316845 - - - 2.199 - 3.217 0.652 - 287.3 1 2 0 0.0054 24 0 0 0 6.16E+07 2.01E+07 - - - 8.5215 0.9998 221125_WJC_METTL3_EV_vs_WT_F08.20847.20847.4 4.19E-06 28/192 K.R[166.11]K[136.11]ELEQVC[160.03]NPIISGLYQGAGGPGPGGFGAQGPK[136.11].G "sp|P0DMV8|HS71A_HUMAN,sp|P0DMV9|HS71B_HUMAN,tr|V9GZ37|V9GZ37_HUMAN,tr|A0A0G2JIW1|A0A0G2JIW1_HUMAN" 4 3364.7197 0.06 122152 20847 4 3364.729033 842.1872 Heat shock 70 kDa protein 1A OS=Homo sapiens OX=9606 GN=HSPA1A PE=1 SV=1 8.18 3417.3 - 612007 - - - 2.7845 - 4.356 0.576 - 437.8 1 2 1 0.0094 33 0 0 0 1.03E+07 1.75E+08 - - - 4.6784 0.9958 221125_WJC_METTL3_EV_vs_WT_F08.20848.20848.4 0.000216 20/198 L.NHSLLTTVGWDHQVVHHVVPTEPLPAPGPASVTE.- "sp|Q9BQA1|MEP50_HUMAN,tr|H0Y711|H0Y711_HUMAN" 2 3620.8376 - 122153 20848 4 3620.842716 906.2167 Methylosome protein 50 OS=Homo sapiens OX=9606 GN=WDR77 PE=1 SV=1 5.64 3417.4 - 433539 - - - 1.4182 - 3.471 0.505 - 163.2 1 1 0 0.0051 34 0 0 0 - - - - - 3.9912 1 221125_WJC_METTL3_EV_vs_WT_F08.20851.20851.3 1.36E-09 14/92 K.YEHDDIVSTVSVLSSGTQAVSGSK[136.11].D "sp|Q9BQA1|MEP50_HUMAN,tr|H0Y711|H0Y711_HUMAN" 2 2473.2064 3.09 122154 20851 3 2473.208686 825.4094 Methylosome protein 50 OS=Homo sapiens OX=9606 GN=WDR77 PE=1 SV=1 4.54 3417.8 - 327286 - - - 0.9332 - 2.836 0.58 - 117.6 1 2 0 0.0023 24 0 0 0 6.16E+07 1.99E+07 - - - 7.4269 1 221125_WJC_METTL3_EV_vs_WT_F08.20854.20854.3 5.08E-07 15/80 K.KDYSQYEENITHLQEQIVDGK.M "sp|Q9C075|K1C23_HUMAN,tr|J3QR55|J3QR55_HUMAN" 2 2536.2082 999 122156 20854 3 2536.207538 846.41 "Keratin, type I cytoskeletal 23 OS=Homo sapiens OX=9606 GN=KRT23 PE=1 SV=2" 4.5 3418.3 - 237725 - - - -0.246 - 2.959 0.543 - 205.7 1 2 0 -0.0006 21 0 0 0 1.01E+07 0.00E+00 - - - 7.1946 0.9999 221125_WJC_METTL3_EV_vs_WT_F08.20866.20866.3 4.03E-06 14/72 K.K[136.11]ISSIQSIVPALEIANAHR[166.11].K "sp|P10809|CH60_HUMAN,tr|A0A7I2V2X6|A0A7I2V2X6_HUMAN,tr|A0A7I2YQK6|A0A7I2YQK6_HUMAN,tr|A0A7I2V599|A0A7I2V599_HUMAN,tr|A0A7I2YQ71|A0A7I2YQ71_HUMAN,tr|A0A7I2V5M1|A0A7I2V5M1_HUMAN,tr|A0A7I2V5K3|A0A7I2V5K3_HUMAN,tr|A0A7I2V369|A0A7I2V369_HUMAN" 8 2064.181 1.23 122162 20866 3 2064.187063 689.0676 "60 kDa heat shock protein, mitochondrial OS=Homo sapiens OX=9606 GN=HSPD1 PE=1 SV=2" 8.75 3419.9 - 201664 - - - 2.9164 - 3.148 0.532 - 225.6 1 2 0 0.006 19 0 0 0 2.25E+07 1.83E+07 - - - 7.287 0.9999 221125_WJC_METTL3_EV_vs_WT_F08.20878.20878.3 4.46E-06 Sep-52 K.K[136.11]GPGEVAGTVTGQK[136.11].R "sp|Q86U44|MTA70_HUMAN,tr|F5H6D8|F5H6D8_HUMAN,tr|H0YFV6|H0YFV6_HUMAN,tr|B4DTN4|B4DTN4_HUMAN" 4 1343.738 0.01 122169 20878 3 1343.739892 448.9199 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 8.59 3421.5 - 121962 - - - 1.4236 - 2.104 0.484 - 128.7 1 2 0 0.0019 14 0 0 0 4.56E+04 6.19E+06 - - - 5.9124 0.999 221125_WJC_METTL3_EV_vs_WT_F08.20889.20889.4 4.16E-07 20/156 K.TKEQASHLGGAVFSGAGNIAAATGLVK.R "sp|Q16143|SYUB_HUMAN,tr|G4Y816|G4Y816_HUMAN" 2 2554.3504 1.47 122175 20889 4 2554.36235 639.5949 Beta-synuclein OS=Homo sapiens OX=9606 GN=SNCB PE=1 SV=1 8.29 3423 - 818907 - - - 4.6979 - 3.52 0.536 - 214 1 2 1 0.012 27 0 0 0 4.58E+08 3.11E+08 - - - 4.2818 1 221125_WJC_METTL3_EV_vs_WT_F08.20899.20899.4 7.59E-12 28/156 K.TK[136.11]EQASHLGGAVFSGAGNIAAATGLVK[136.11].R "sp|Q16143|SYUB_HUMAN,tr|G4Y816|G4Y816_HUMAN" 2 2570.3787 1.5 122181 20899 4 2570.378866 643.602 Beta-synuclein OS=Homo sapiens OX=9606 GN=SNCB PE=1 SV=1 8.29 3424.4 - 966873 - - - 0.0451 - 4.557 0.638 - 402.5 1 2 1 0.0001 27 0 0 0 4.57E+08 3.05E+08 - - - 5.2537 0.9997 221125_WJC_METTL3_EV_vs_WT_F08.20900.20900.4 0.00274 Oct-84 R.STSHK[136.11]PDEIYGMIER[166.11].L sp|Q86U44|MTA70_HUMAN 1 1779.8581 0.01 122182 20900 4 1779.858359 445.9718 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 5.42 3424.5 - 154979 - - - 0.1714 - 1.677 0.361 - 48.6 1 2 0 0.0003 15 0 0 0 5.43E+04 9.85E+06 - - - 2.553 1 221125_WJC_METTL3_EV_vs_WT_F08.20901.20901.4 1.52E-11 24/186 K.SIDDTSNFDEFPESDILKPTVATSNHPETDYK.N sp|Q15208|STK38_HUMAN 1 3611.6427 3.8 122183 20901 4 3611.646146 903.918 Serine\threonine-protein kinase 38 OS=Homo sapiens OX=9606 GN=STK38 PE=1 SV=1 4.02 3424.6 - 1.34E+06 - - - 0.9408 - 4.338 0.692 - 234.6 1 2 0 0.0034 32 0 0 0 2.82E+09 7.41E+08 - - - 5.6913 1 221125_WJC_METTL3_EV_vs_WT_F08.20903.20903.3 6.68E-14 18/104 K.TKEQASHLGGAVFSGAGNIAAATGLVK.R "sp|Q16143|SYUB_HUMAN,tr|G4Y816|G4Y816_HUMAN" 2 2554.3504 1.42 122185 20903 3 2554.351189 852.4574 Beta-synuclein OS=Homo sapiens OX=9606 GN=SNCB PE=1 SV=1 8.29 3424.9 - 250890 - - - 0.3285 - 3.973 0.736 - 288.7 1 2 1 0.0008 27 0 0 0 1.35E+08 9.56E+07 - - - 9.9192 1 221125_WJC_METTL3_EV_vs_WT_F08.20909.20909.3 3.40E-11 19/104 K.TK[136.11]EQASHLGGAVFSGAGNIAAATGLVK[136.11].R "sp|Q16143|SYUB_HUMAN,tr|G4Y816|G4Y816_HUMAN" 2 2570.3787 1.41 122189 20909 3 2570.381761 857.8002 Beta-synuclein OS=Homo sapiens OX=9606 GN=SNCB PE=1 SV=1 8.29 3425.7 - 430301 - - - 1.1714 - 3.885 0.656 - 292.8 1 2 1 0.003 27 0 0 0 1.35E+08 9.57E+07 - - - 8.9752 1 221125_WJC_METTL3_EV_vs_WT_F08.20921.20921.4 4.07E-12 26/264 R.RPPGGTSPPNGGLPGPLATSAAPPGPPAAASPC[160.03]LGPVAAAGSGLR.R "sp|Q8WWM7|ATX2L_HUMAN,tr|H3BUF6|H3BUF6_HUMAN" 2 4023.0749 5.56 122196 20921 4 4023.073853 1006.776 Ataxin-2-like protein OS=Homo sapiens OX=9606 GN=ATXN2L PE=1 SV=2 10.35 3427.3 - 264473 - - - -0.2523 - 4.265 0.652 - 245 1 2 0 -0.001 45 0 0 0 2.13E+07 3.83E+06 - - - 5.3099 1 221125_WJC_METTL3_EV_vs_WT_F08.20924.20924.3 7.35E-08 16/104 R.GSSGGGC[160.03]FGGSSGGYGGLGGFGGGSFR.G "sp|P13645|K1C10_HUMAN,tr|A0A1B0GVI3|A0A1B0GVI3_HUMAN" 2 2341.9771 103.12 122197 20924 3 2341.982607 781.6663 "Keratin, type I cytoskeletal 10 OS=Homo sapiens OX=9606 GN=KRT10 PE=1 SV=6" 8.22 3427.7 - 450552 - - - 2.3698 - 2.966 0.587 - 144.9 1 2 0 0.0056 27 0 0 0 1.27E+07 1.23E+05 - - - 7.5842 1 221125_WJC_METTL3_EV_vs_WT_F08.20925.20925.4 5.55E-11 30/192 K.RKELEQVC[160.03]NPIISGLYQGAGGPGPGGFGAQGPK.G "sp|P0DMV8|HS71A_HUMAN,sp|P0DMV9|HS71B_HUMAN,tr|V9GZ37|V9GZ37_HUMAN,tr|A0A0G2JIW1|A0A0G2JIW1_HUMAN" 4 3338.683 0.06 122198 20925 4 3338.693743 835.678 Heat shock 70 kDa protein 1A OS=Homo sapiens OX=9606 GN=HSPA1A PE=1 SV=1 8.18 3427.9 - 499722 - - - 3.2195 - 5.409 0.637 - 585.9 1 2 1 0.0107 33 0 0 0 1.03E+07 1.75E+08 - - - 5.2739 0.9998 221125_WJC_METTL3_EV_vs_WT_F08.20928.20928.3 0.000161 Nov-68 R.SPSELFAQHIVTIVHHVK.E "sp|Q9Y2W1|TR150_HUMAN,tr|A0A3B3ITZ9|A0A3B3ITZ9_HUMAN" 2 2041.1109 2.91 122201 20928 3 2041.11548 681.3776 Thyroid hormone receptor-associated protein 3 OS=Homo sapiens OX=9606 GN=THRAP3 PE=1 SV=2 6.78 3428.3 - 221393 - - - 2.2463 - 2.437 0.418 - 126.2 1 2 0 0.0046 18 0 0 0 4.04E+07 1.39E+07 - - - 5.4171 1 221125_WJC_METTL3_EV_vs_WT_F08.20932.20932.3 1.19E-06 13/64 R.AETEC[160.03]QNTEYQQLLDIK.L "sp|P13645|K1C10_HUMAN,tr|A0A1B0GVI3|A0A1B0GVI3_HUMAN" 2 2081.9576 794.46 122203 20932 3 2081.960442 694.9931 "Keratin, type I cytoskeletal 10 OS=Homo sapiens OX=9606 GN=KRT10 PE=1 SV=6" 4 3428.8 - 335573 - - - 1.3891 - 2.607 0.559 - 247.2 1 2 0 0.0029 17 0 0 0 3.43E+07 4.31E+04 - - - 7.1922 1 221125_WJC_METTL3_EV_vs_WT_F08.20933.20933.3 4.40E-13 21/124 K.SIDDTSNFDEFPESDILKPTVATSNHPETDYK.N sp|Q15208|STK38_HUMAN 1 3611.6427 4.71 122204 20933 3 3611.650089 1204.8882 Serine\threonine-protein kinase 38 OS=Homo sapiens OX=9606 GN=STK38 PE=1 SV=1 4.02 3428.9 - 479407 - - - 2.0326 - 3.688 0.702 - 232.2 1 2 0 0.0073 32 0 0 0 1.39E+08 2.95E+07 - - - 9.3671 1 221125_WJC_METTL3_EV_vs_WT_F08.20938.20938.4 3.06E-05 23/108 K.K[136.11]ISSIQSIVPALEIANAHR[166.11].K "sp|P10809|CH60_HUMAN,tr|A0A7I2V2X6|A0A7I2V2X6_HUMAN,tr|A0A7I2YQK6|A0A7I2YQK6_HUMAN,tr|A0A7I2V599|A0A7I2V599_HUMAN,tr|A0A7I2YQ71|A0A7I2YQ71_HUMAN,tr|A0A7I2V5M1|A0A7I2V5M1_HUMAN,tr|A0A7I2V5K3|A0A7I2V5K3_HUMAN,tr|A0A7I2V369|A0A7I2V369_HUMAN" 8 2064.181 1.29 122208 20938 4 2064.182512 517.0525 "60 kDa heat shock protein, mitochondrial OS=Homo sapiens OX=9606 GN=HSPD1 PE=1 SV=2" 8.75 3429.5 - 1.07E+06 - - - 0.7117 - 3.988 0.561 - 592.2 1 2 0 0.0015 19 0 0 0 4.81E+07 3.72E+07 - - - 4.5765 1 221125_WJC_METTL3_EV_vs_WT_F08.20940.20940.4 2.17E-06 19/108 K.KISSIQSIVPALEIANAHR.K "sp|P10809|CH60_HUMAN,tr|A0A7I2V2X6|A0A7I2V2X6_HUMAN,tr|A0A7I2YQK6|A0A7I2YQK6_HUMAN,tr|A0A7I2V599|A0A7I2V599_HUMAN,tr|A0A7I2YQ71|A0A7I2YQ71_HUMAN,tr|A0A7I2V5M1|A0A7I2V5M1_HUMAN,tr|A0A7I2V5K3|A0A7I2V5K3_HUMAN,tr|A0A7I2V369|A0A7I2V369_HUMAN" 8 2046.1586 1.29 122209 20940 4 2046.158137 512.5469 "60 kDa heat shock protein, mitochondrial OS=Homo sapiens OX=9606 GN=HSPD1 PE=1 SV=2" 8.75 3429.7 - 1.32E+06 - - - -0.2131 - 3.27 0.509 - 282.8 1 2 0 -0.0004 19 0 0 0 5.11E+07 3.94E+07 - - - 4.057 1 221125_WJC_METTL3_EV_vs_WT_F08.20942.20942.3 3.28E-10 19/72 K.SKELTTEIDNNIEQISSYK.S "sp|P13645|K1C10_HUMAN,tr|A0A1B0GVI3|A0A1B0GVI3_HUMAN" 2 2211.0907 158.87 122211 20942 3 2211.091203 738.0375 "Keratin, type I cytoskeletal 10 OS=Homo sapiens OX=9606 GN=KRT10 PE=1 SV=6" 4.41 3429.9 - 4.79E+06 - - - 0.2397 - 3.76 0.618 - 358.6 1 2 1 0.0005 19 0 0 0 3.05E+08 1.92E+06 - - - 8.6838 1 221125_WJC_METTL3_EV_vs_WT_F08.20943.20943.4 3.07E-12 18/132 K.HTDESLGDC[160.03]SFLNTC[160.03]FHMDTC[160.03]K[136.11]Y.V "sp|Q86U44|MTA70_HUMAN,tr|H0YFV6|H0YFV6_HUMAN" 2 2845.1332 0.001 122212 20943 4 2846.135726 712.2906 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 4.64 3430.1 - 480091 - - - 352.3751 - 3.456 0.732 - 208.2 1 1 0 1.0026 23 0 0 0 0.00E+00 2.19E+07 - - - 5.7214 0.9989 221125_WJC_METTL3_EV_vs_WT_F08.20954.20954.3 2.32E-07 18/124 A.GSSLTSFGTETSNSGTLPQSSAVGSAFTQDTR[166.11].S "sp|Q8ND56|LS14A_HUMAN,tr|A0A140TA76|A0A140TA76_HUMAN,tr|K7EMZ9|K7EMZ9_HUMAN" 3 3187.4781 1.16 122218 20954 3 3187.477609 1063.5 Protein LSM14 homolog A OS=Homo sapiens OX=9606 GN=LSM14A PE=1 SV=3 4.37 3431.6 - 589260 - - - -0.1475 - 3.187 0.631 - 247.9 1 1 0 -0.0005 32 0 0 0 4.25E+07 3.67E+07 - - - 8.2415 0.9999 221125_WJC_METTL3_EV_vs_WT_F08.20957.20957.4 1.77E-08 17/162 R.THSGLTDGIPLQSISAPGSGIWSDGKDK.S sp|A5YKK6|CNOT1_HUMAN 1 2823.4039 1.06 122220 20957 4 2823.401259 706.8583 CCR4-NOT transcription complex subunit 1 OS=Homo sapiens OX=9606 GN=CNOT1 PE=1 SV=2 5.27 3431.9 - 301488 - - - -0.9361 - 3.491 0.611 - 175.3 1 2 1 -0.0026 28 0 0 0 1.46E+07 1.38E+07 - - - 4.9316 0.9982 221125_WJC_METTL3_EV_vs_WT_F08.20958.20958.4 6.96E-10 19/114 K.HAASDVDLEIESLLNQQSTK[136.11].E "sp|Q86U44|MTA70_HUMAN,tr|F5H6D8|F5H6D8_HUMAN,tr|H0YFV6|H0YFV6_HUMAN,tr|B4DTN4|B4DTN4_HUMAN" 4 2205.1005 0.02 122221 20958 4 2206.096941 552.2824 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 4.31 3432 - 1.11E+06 - - - 451.9 - 3.501 0.606 - 322.3 1 2 0 0.9965 20 0 0 0 8.69E+05 3.88E+07 - - - 4.6435 1 221125_WJC_METTL3_EV_vs_WT_F08.20968.20968.3 5.71E-09 16/124 K.SIDDTSNFDEFPESDILK[136.11]PTVATSNHPETDYK[136.11].N sp|Q15208|STK38_HUMAN 1 3627.6711 4.71 122224 20968 3 3627.659473 1210.231 Serine\threonine-protein kinase 38 OS=Homo sapiens OX=9606 GN=STK38 PE=1 SV=1 4.02 3433.5 - 471644 - - - -3.2183 - 3.025 0.649 - 120 1 2 0 -0.0117 32 0 0 0 1.39E+08 2.95E+07 - - - 8.3191 0.9999 221125_WJC_METTL3_EV_vs_WT_F08.20975.20975.3 0.00403 Dec-56 R.STSHK[136.11]PDEIYGMIER[166.11].L sp|Q86U44|MTA70_HUMAN 1 1779.8581 0.1 122227 20975 3 1779.857735 594.2933 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 5.42 3434.4 - 302719 - - - -0.1792 - 2.564 0.409 - 156.2 1 2 0 -0.0003 15 0 0 0 9.99E+05 1.02E+07 - - - 5.5568 0.9999 221125_WJC_METTL3_EV_vs_WT_F08.20983.20983.3 1.60E-06 9/104 R.QPSGDSGLAAETSAISQDLEGVPPSKK.M sp|Q4VC05|BCL7A_HUMAN 1 2668.3192 1.82 122230 20983 3 2668.314475 890.447 B-cell CLL\lymphoma 7 protein family member A OS=Homo sapiens OX=9606 GN=BCL7A PE=1 SV=1 4.32 3435.5 - 392715 - - - -1.7592 - 2.479 0.508 - 26.9 1 2 0 -0.0047 27 0 0 0 2.42E+07 1.33E+07 - - - 6.291 1 221125_WJC_METTL3_EV_vs_WT_F08.21002.21002.4 1.40E-09 18/186 K.LKEPGGGSFRDDDDINDVASMAGVNLSEESAR.L "sp|O00268|TAF4_HUMAN,tr|V9GY14|V9GY14_HUMAN,tr|A0A0G2JRY5|A0A0G2JRY5_HUMAN" 3 3350.5321 5.83 122235 21002 4 3350.532258 838.6403 Transcription initiation factor TFIID subunit 4 OS=Homo sapiens OX=9606 GN=TAF4 PE=1 SV=2 4.03 3438.2 - 561374 - - - 0.0495 - 3.349 0.683 - 100.3 1 2 2 0.0002 32 0 0 0 2.70E+07 4.63E+06 - - - 5.5357 0.9998 221125_WJC_METTL3_EV_vs_WT_F08.21008.21008.3 14.8 Nov-56 R.GFGFVTFDDHDPVDK[136.11].L "sp|P22626|ROA2_HUMAN,tr|A0A7I2V4N0|A0A7I2V4N0_HUMAN,tr|A0A024RA28|A0A024RA28_HUMAN,tr|A0A7I2V4N1|A0A7I2V4N1_HUMAN,tr|A0A7I2V4I6|A0A7I2V4I6_HUMAN,tr|A0A087WUI2|A0A087WUI2_HUMAN,tr|A0A7I2V4S4|A0A7I2V4S4_HUMAN,tr|A0A7I2V323|A0A7I2V323_HUMAN,tr|A0A7I2V3P1|A0A7I2V3P1_HUMAN,tr|A0A7I2V3P7|A0A7I2V3P7_HUMAN" 10 1702.7719 1.23 122238 21008 3 1702.769216 568.5979 Heterogeneous nuclear ribonucleoproteins A2\B1 OS=Homo sapiens OX=9606 GN=HNRNPA2B1 PE=1 SV=2 4.13 3439 - 350790 - - - -1.5475 - 2.353 0.361 - 96.1 1 2 0 -0.0026 15 0 0 0 1.25E+07 1.02E+07 - - - 4.7969 1 221125_WJC_METTL3_EV_vs_WT_F08.21021.21021.4 4.12E-08 15/120 R.K[136.11]HAASDVDLEIESLLNQQSTK[136.11].E "sp|Q86U44|MTA70_HUMAN,tr|F5H6D8|F5H6D8_HUMAN,tr|H0YFV6|H0YFV6_HUMAN,tr|B4DTN4|B4DTN4_HUMAN" 4 2341.2096 0.34 122246 21021 4 2341.209754 586.3097 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 4.75 3440.6 - 397993 - - - 0.0577 - 3.532 0.526 - 145.5 1 2 0 0.0001 21 0 0 0 1.80E+07 5.24E+07 - - - 4.2215 1 221125_WJC_METTL3_EV_vs_WT_F08.21024.21024.3 2.09E-06 Dec-56 R.GFGFVTFDDHDPVDK.L "sp|P22626|ROA2_HUMAN,tr|A0A7I2V4N0|A0A7I2V4N0_HUMAN,tr|A0A024RA28|A0A024RA28_HUMAN,tr|A0A7I2V4N1|A0A7I2V4N1_HUMAN,tr|A0A7I2V4I6|A0A7I2V4I6_HUMAN,tr|A0A087WUI2|A0A087WUI2_HUMAN,tr|A0A7I2V4S4|A0A7I2V4S4_HUMAN,tr|A0A7I2V323|A0A7I2V323_HUMAN,tr|A0A7I2V3P1|A0A7I2V3P1_HUMAN,tr|A0A7I2V3P7|A0A7I2V3P7_HUMAN" 10 1694.7577 1.23 122247 21024 3 1694.755998 565.9265 Heterogeneous nuclear ribonucleoproteins A2\B1 OS=Homo sapiens OX=9606 GN=HNRNPA2B1 PE=1 SV=2 4.13 3440.9 - 475485 - - - -0.9754 - 2.034 0.563 - 98.4 1 2 0 -0.0017 15 0 0 0 1.25E+07 1.02E+07 - - - 6.6691 0.9999 221125_WJC_METTL3_EV_vs_WT_F08.21028.21028.4 6.44E-08 17/126 K.KQC[160.03]ANLQNAIADAEQRGELALK.D "sp|P13647|K2C5_HUMAN,tr|H0YI76|H0YI76_HUMAN" 2 2440.2493 8.92 122249 21028 4 2440.251601 611.0696 "Keratin, type II cytoskeletal 5 OS=Homo sapiens OX=9606 GN=KRT5 PE=1 SV=3" 6.17 3441.4 - 450595 - - - 0.961 - 3.271 0.549 - 210.4 1 2 1 0.0023 22 0 0 0 2.10E+07 2.36E+06 - - - 4.3916 0.998 221125_WJC_METTL3_EV_vs_WT_F08.21030.21030.4 1.49E-05 11/138 R.IGNSGVEEIKGHPFFEGVDWEHIR.E sp|Q9Y2H1|ST38L_HUMAN 1 2751.3405 5.63 122250 21030 4 2751.330967 688.8424 Serine\threonine-protein kinase 38-like OS=Homo sapiens OX=9606 GN=STK38L PE=1 SV=3 4.92 3441.6 - 322959 - - - -3.4699 - 2.468 0.412 - 65.8 1 2 1 -0.0095 24 0 0 0 8.07E+06 1.43E+06 - - - 3.0994 0.9855 221125_WJC_METTL3_EV_vs_WT_F08.21044.21044.4 8.49E-08 20/156 T.TVAAFASSLVSGLNSSASEPAK[136.11]EPAK[136.11]K[136.11].S "sp|Q86U44|MTA70_HUMAN,tr|F5H6D8|F5H6D8_HUMAN,tr|H0YFV6|H0YFV6_HUMAN,tr|B4DTN4|B4DTN4_HUMAN" 4 2670.4291 0.02 122256 21044 4 2670.429212 668.6145 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 8.17 3443.4 - 678099 - - - 0.0565 - 3.667 0.504 - 191.9 1 1 1 0.0002 27 0 0 0 1.74E+06 1.13E+08 - - - 4.0193 1 221125_WJC_METTL3_EV_vs_WT_F08.21048.21048.4 1.15E-11 25/174 R.VPLVAPEDLRDDIIENAPTTHTEEYSGEEK.T "sp|O14744|ANM5_HUMAN,tr|G3V580|G3V580_HUMAN,tr|G3V2X6|G3V2X6_HUMAN,tr|G3V5L5|G3V5L5_HUMAN,tr|H0YJX6|H0YJX6_HUMAN" 5 3366.6103 3.27 122258 21048 4 3366.605846 842.6599 Protein arginine N-methyltransferase 5 OS=Homo sapiens OX=9606 GN=PRMT5 PE=1 SV=4 4.05 3443.9 - 1.35E+06 - - - -1.3307 - 4.258 0.662 - 250.1 1 2 1 -0.0045 30 0 0 0 1.30E+08 3.99E+07 - - - 5.4301 0.9149 221125_WJC_METTL3_EV_vs_WT_F08.21053.21053.3 0.0299 Sep-84 K.HTDESLGDC[160.03]SFLNTC[160.03]FHMDTC[160.03]K.Y "sp|Q86U44|MTA70_HUMAN,tr|H0YFV6|H0YFV6_HUMAN" 2 2674.0556 -1 122260 21053 3 2674.035379 892.3592 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 4.64 3444.6 - 1.16E+06 - - - -7.578 - 1.692 0.314 - 70.5 1 2 0 -0.0203 22 0 0 0 0.00E+00 0.00E+00 - - - 3.282 1 221125_WJC_METTL3_EV_vs_WT_F08.21058.21058.4 4.33E-11 15/126 K.HTDESLGDC[160.03]SFLNTC[160.03]FHMDTC[160.03]K[136.11].Y "sp|Q86U44|MTA70_HUMAN,tr|H0YFV6|H0YFV6_HUMAN" 2 2682.0698 0.04 122262 21058 4 2682.079202 671.5247 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 4.64 3445.2 - 164398 - - - 3.4891 - 3.601 0.706 - 201.1 1 2 0 0.0094 22 0 0 0 8.18E+05 2.17E+07 - - - 5.7876 0.7839 221125_WJC_METTL3_EV_vs_WT_F08.21060.21060.4 2.27E-06 19/132 K.AENGK[136.11]LVINGNPITIFQER[166.11]DPSK[136.11].L sp|P04406|G3P_HUMAN 1 2565.3761 1.49 122263 21060 4 2566.362089 642.3513 Glyceraldehyde-3-phosphate dehydrogenase OS=Homo sapiens OX=9606 GN=GAPDH PE=1 SV=3 6.23 3445.4 - 780911 - - - 384.3366 - 3.618 0.494 - 249.5 1 2 2 0.986 23 0 0 0 8.98E+06 6.05E+06 - - - 3.6693 1 221125_WJC_METTL3_EV_vs_WT_F08.21066.21066.3 4.32E-10 26/80 R.K[136.11]HAASDVDLEIESLLNQQSTK[136.11].E "sp|Q86U44|MTA70_HUMAN,tr|F5H6D8|F5H6D8_HUMAN,tr|H0YFV6|H0YFV6_HUMAN,tr|B4DTN4|B4DTN4_HUMAN" 4 2341.2096 0.22 122267 21066 3 2341.206845 781.4105 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 4.75 3446.1 - 653393 - - - -1.1849 - 4.714 0.617 - 1057.4 1 2 0 -0.0028 21 0 0 0 6.09E+06 2.81E+07 - - - 9.1355 0.9998 221125_WJC_METTL3_EV_vs_WT_F08.21067.21067.2 5.10E-06 18-Oct R.EC[160.03]LNLWGYER[166.11].V sp|Q86U44|MTA70_HUMAN 1 1348.6109 0.02 122268 21067 2 1348.608582 675.3127 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 4.53 3446.3 - 308510 - - - -1.7492 - 2.109 0.588 - 511.2 1 2 0 -0.0024 10 0 0 0 9.30E+05 4.29E+07 - - - 5.4661 1 221125_WJC_METTL3_EV_vs_WT_F08.21073.21073.4 4.23E-08 19/174 R.VPLVAPEDLR[166.11]DDIIENAPTTHTEEYSGEEK[136.11].T "sp|O14744|ANM5_HUMAN,tr|G3V580|G3V580_HUMAN,tr|G3V2X6|G3V2X6_HUMAN,tr|G3V5L5|G3V5L5_HUMAN,tr|H0YJX6|H0YJX6_HUMAN" 5 3384.6328 3.27 122271 21073 4 3384.633507 847.1655 Protein arginine N-methyltransferase 5 OS=Homo sapiens OX=9606 GN=PRMT5 PE=1 SV=4 4.05 3447 - 882286 - - - 0.2101 - 3.723 0.626 - 153.6 1 2 1 0.0007 30 0 0 0 1.30E+08 3.99E+07 - - - 5.0768 1 221125_WJC_METTL3_EV_vs_WT_F08.21079.21079.3 6.07E-09 23/120 K.SNEVVAVPTNGTVNNVAQEPVNTLGDISGNK.T "sp|Q9Y520|PRC2C_HUMAN,tr|E7EPN9|E7EPN9_HUMAN" 2 3136.5637 1.43 122274 21079 3 3136.566532 1046.5285 Protein PRRC2C OS=Homo sapiens OX=9606 GN=PRRC2C PE=1 SV=4 4.14 3447.8 - 630819 - - - 0.9188 - 4.171 0.639 - 374.9 1 2 0 0.0029 31 0 0 0 3.92E+07 2.74E+07 - - - 8.9491 0.9995 221125_WJC_METTL3_EV_vs_WT_F08.21087.21087.4 4.91E-05 10/144 K.FGDPVVQSDMK[136.11]HWPFQVINDGDK[136.11]PK[136.11].V "sp|P0DMV8|HS71A_HUMAN,sp|P0DMV9|HS71B_HUMAN,tr|A0A0G2JIW1|A0A0G2JIW1_HUMAN" 3 2907.444 0.08 122279 21087 4 2907.451438 727.8683 Heat shock 70 kDa protein 1A OS=Homo sapiens OX=9606 GN=HSPA1A PE=1 SV=1 5.36 3448.9 - 260634 - - - 2.5586 - 2.117 0.475 - 33.3 1 2 1 0.0074 25 0 0 0 6.85E+05 8.28E+06 - - - 3.5969 1 221125_WJC_METTL3_EV_vs_WT_F08.21089.21089.3 5.91E-10 17/120 K.SNEVVAVPTNGTVNNVAQEPVNTLGDISGNK[136.11].T "sp|Q9Y520|PRC2C_HUMAN,tr|E7EPN9|E7EPN9_HUMAN" 2 3144.5779 1.43 122281 21089 3 3144.578571 1049.1999 Protein PRRC2C OS=Homo sapiens OX=9606 GN=PRRC2C PE=1 SV=4 4.14 3449.2 - 850689 - - - 0.2293 - 3.707 0.628 - 250.7 1 2 0 0.0007 31 0 0 0 3.92E+07 2.74E+07 - - - 8.5557 1 221125_WJC_METTL3_EV_vs_WT_F08.21095.21095.4 1.50E-06 13/186 K.SIDDTSNFDEFPESDILK[136.11]PTVATSNHPETDYK[136.11].N sp|Q15208|STK38_HUMAN 1 3627.6711 3.81 122284 21095 4 3627.672716 907.9251 Serine\threonine-protein kinase 38 OS=Homo sapiens OX=9606 GN=STK38 PE=1 SV=1 4.02 3450.1 - 584913 - - - 0.4322 - 2.455 0.487 - 66.5 1 2 0 0.0016 32 0 0 0 2.83E+09 7.44E+08 - - - 3.7356 0.9998 221125_WJC_METTL3_EV_vs_WT_F08.21116.21116.3 0.000351 Jul-52 K.K[136.11]GPGEVAGTVTGQK[136.11].R "sp|Q86U44|MTA70_HUMAN,tr|F5H6D8|F5H6D8_HUMAN,tr|H0YFV6|H0YFV6_HUMAN,tr|B4DTN4|B4DTN4_HUMAN" 4 1343.738 0.001 122293 21116 3 1343.738416 448.9199 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 8.59 3452.8 - 128844 - - - 0.3252 - 1.745 0.428 - 75.3 1 2 0 0.0004 14 0 0 0 0.00E+00 4.42E+06 - - - 4.7912 1 221125_WJC_METTL3_EV_vs_WT_F08.21130.21130.3 1.26E-16 24/140 K.LAQQQASAAAAAAAATAAATAATTTSAGVSHQNPSK.N "sp|O60907|TBL1X_HUMAN,tr|A0A804HJZ5|A0A804HJZ5_HUMAN,tr|A0A2R8YFW3|A0A2R8YFW3_HUMAN" 3 3265.6287 2.4 122302 21130 3 3265.637301 1089.5502 F-box-like\WD repeat-containing protein TBL1X OS=Homo sapiens OX=9606 GN=TBL1X PE=1 SV=3 8.76 3454.6 - 203409 - - - 2.6307 - 5.881 0.719 - 579.9 1 2 0 0.0086 36 0 0 0 2.72E+07 1.13E+07 - - - 10.6299 1 221125_WJC_METTL3_EV_vs_WT_F08.21132.21132.4 7.26E-11 20/186 K.SIDDTSNFDEFPESDILKPTVATSNHPETDYK.N sp|Q15208|STK38_HUMAN 1 3611.6427 3.8 122303 21132 4 3611.646575 903.918 Serine\threonine-protein kinase 38 OS=Homo sapiens OX=9606 GN=STK38 PE=1 SV=1 4.02 3454.8 - 510272 - - - 1.0596 - 3.473 0.681 - 190.6 1 2 0 0.0038 32 0 0 0 2.82E+09 7.41E+08 - - - 5.5283 1 221125_WJC_METTL3_EV_vs_WT_F08.21140.21140.3 5.59E-06 10/128 R.SDSPVPTAPTSGGPK[136.11]PSTASAVPELATDPELEK[136.11].K "sp|Q86U44|MTA70_HUMAN,tr|B4E349|B4E349_HUMAN,tr|F5H6D8|F5H6D8_HUMAN,tr|B4DTN4|B4DTN4_HUMAN" 4 3248.6271 0.001 122307 21140 3 3248.629664 1083.883 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 4.18 3455.8 - 266381 - - - 0.7899 - 2.182 0.543 - 41.3 1 2 0 0.0026 33 0 0 0 0.00E+00 1.61E+07 - - - 6.3883 1 221125_WJC_METTL3_EV_vs_WT_F08.21146.21146.3 1.59E-11 17/140 K.LAQQQASAAAAAAAATAAATAATTTSAGVSHQNPSK[136.11].N "sp|O60907|TBL1X_HUMAN,tr|A0A804HJZ5|A0A804HJZ5_HUMAN,tr|A0A2R8YFW3|A0A2R8YFW3_HUMAN" 3 3273.6429 2.37 122311 21146 3 3273.642411 1092.2216 F-box-like\WD repeat-containing protein TBL1X OS=Homo sapiens OX=9606 GN=TBL1X PE=1 SV=3 8.76 3456.6 - 208817 - - - -0.1524 - 4.923 0.614 - 219.8 1 2 0 -0.0005 36 0 0 0 2.69E+07 1.13E+07 - - - 9.0524 1 221125_WJC_METTL3_EV_vs_WT_F08.21151.21151.4 2.61E-09 16/144 K.KKPEDSPSDDDVLIVYELTPTAEQK.A sp|P49792|RBP2_HUMAN 1 2816.3968 1.14 122314 21151 4 2816.398635 705.1065 E3 SUMO-protein ligase RanBP2 OS=Homo sapiens OX=9606 GN=RANBP2 PE=1 SV=2 4.14 3457.3 - 549877 - - - 0.6689 - 3.829 0.596 - 145.6 1 2 0 0.0019 25 0 0 0 1.88E+07 1.65E+07 - - - 4.8402 1 221125_WJC_METTL3_EV_vs_WT_F08.21152.21152.4 4.11E-09 24/198 R.GDPQQQSITHIAIPQEAYNAVHVSGSPTALAAVK.L sp|Q2TAL8|QRIC1_HUMAN 1 3497.7903 1.73 122315 21152 4 3497.784097 875.4549 Transcriptional regulator QRICH1 OS=Homo sapiens OX=9606 GN=QRICH1 PE=1 SV=1 5.99 3457.4 - 480182 - - - -1.7723 - 3.745 0.619 - 223.6 1 2 0 -0.0062 34 0 0 0 3.90E+07 2.26E+07 - - - 5.0058 1 221125_WJC_METTL3_EV_vs_WT_F08.21158.21158.4 8.25E-19 46/210 K.LAQQQASAAAAAAAATAAATAATTTSAGVSHQNPSK.N "sp|O60907|TBL1X_HUMAN,tr|A0A804HJZ5|A0A804HJZ5_HUMAN,tr|A0A2R8YFW3|A0A2R8YFW3_HUMAN" 3 3265.6287 1.75 122319 21158 4 3265.628959 817.4145 F-box-like\WD repeat-containing protein TBL1X OS=Homo sapiens OX=9606 GN=TBL1X PE=1 SV=3 8.76 3458.2 - 4.58E+06 - - - 0.0762 - 7.89 0.691 - 1526.2 1 2 0 0.0002 36 0 0 0 1.56E+08 8.91E+07 - - - 5.8493 1 221125_WJC_METTL3_EV_vs_WT_F08.21159.21159.4 1.08E-08 20/198 R.GDPQQQSITHIAIPQEAYNAVHVSGSPTALAAVK[136.11].L sp|Q2TAL8|QRIC1_HUMAN 1 3505.8045 1.73 122320 21159 4 3505.802836 877.4584 Transcriptional regulator QRICH1 OS=Homo sapiens OX=9606 GN=QRICH1 PE=1 SV=1 5.99 3458.4 - 548765 - - - -0.4735 - 3.926 0.582 - 135.7 1 2 0 -0.0017 34 0 0 0 3.89E+07 2.25E+07 - - - 4.6991 0.9998 221125_WJC_METTL3_EV_vs_WT_F08.21164.21164.4 2.18E-05 16/144 K.AKWETYFDHENTVDAPFC[160.03]LNANENK.S sp|Q96P63|SPB12_HUMAN 1 3012.3348 144.62 122322 21164 4 3012.331108 754.091 Serpin B12 OS=Homo sapiens OX=9606 GN=SERPINB12 PE=1 SV=1 4.5 3459.1 - 986040 - - - -1.2376 - 2.909 0.465 - 136.1 1 2 1 -0.0037 25 0 0 0 4.00E+07 2.76E+05 - - - 3.612 0.9997 221125_WJC_METTL3_EV_vs_WT_F08.21175.21175.2 7.84E-06 22-Oct K.DAGTIAGLNVLR[166.11].L "sp|P11142|HSP7C_HUMAN,tr|E9PQQ4|E9PQQ4_HUMAN,tr|E9PKE3|E9PKE3_HUMAN,tr|E9PN89|E9PN89_HUMAN,tr|E9PLF4|E9PLF4_HUMAN,tr|E9PI65|E9PI65_HUMAN,tr|E9PK54|E9PK54_HUMAN,tr|E9PQK7|E9PQK7_HUMAN" 8 1208.6753 1.91 122328 21175 2 1208.672881 605.3449 Heat shock cognate 71 kDa protein OS=Homo sapiens OX=9606 GN=HSPA8 PE=1 SV=1 5.84 3460.5 - 399168 - - - -1.965 - 2.098 0.523 - 308.9 1 2 0 -0.0024 12 0 0 0 3.49E+07 1.82E+07 - - - 4.8528 0.9997 221125_WJC_METTL3_EV_vs_WT_F08.21176.21176.4 0.000599 11/132 K.HSTGIDIGDSLTIPDEFTEDEKK.S "sp|Q6NUK1|SCMC1_HUMAN,tr|A0A3B3IU96|A0A3B3IU96_HUMAN" 2 2546.2024 1.54 122329 21176 4 2546.208478 637.5579 Calcium-binding mitochondrial carrier protein SCaMC-1 OS=Homo sapiens OX=9606 GN=SLC25A24 PE=1 SV=2 4.14 3460.6 - 303671 - - - 2.3839 - 1.909 0.403 - 62.9 1 2 0 0.0061 23 0 0 0 5.74E+06 3.72E+06 - - - 2.9415 0.9999 221125_WJC_METTL3_EV_vs_WT_F08.21178.21178.3 7.57E-08 14/80 R.LASYLDKVQALEEANNDLENK.L sp|P35527|K1C9_HUMAN 1 2376.1809 999 122331 21178 3 2376.184581 793.0676 "Keratin, type I cytoskeletal 9 OS=Homo sapiens OX=9606 GN=KRT9 PE=1 SV=3" 4.18 3460.8 - 442947 - - - 1.5554 - 3.361 0.614 - 176.2 1 2 1 0.0037 21 0 0 0 1.54E+07 0.00E+00 - - - 8.2908 0.9999 221125_WJC_METTL3_EV_vs_WT_F08.21206.21206.4 0.000237 11/186 K.VGGTNLGAPGAFGQSPFSQPPAPPHQNTFPPR.S sp|Q96I24|FUBP3_HUMAN 1 3227.5901 6.45 122344 21206 4 3227.591486 807.9048 Far upstream element-binding protein 3 OS=Homo sapiens OX=9606 GN=FUBP3 PE=1 SV=2 9.73 3464.5 - 251439 - - - 0.4356 - 2.112 0.428 - 33.3 1 2 0 0.0014 32 0 0 0 6.08E+06 9.43E+05 - - - 3.1767 0.9999 221125_WJC_METTL3_EV_vs_WT_F08.21210.21210.3 6.37E-07 Dec-48 R.KVESLQEEIAFLK.K "sp|P08670|VIME_HUMAN,tr|B0YJC5|B0YJC5_HUMAN,tr|B0YJC4|B0YJC4_HUMAN" 3 1532.845 1.92 122346 21210 3 1532.847345 511.9556 Vimentin OS=Homo sapiens OX=9606 GN=VIM PE=1 SV=4 4.79 3465 - 238957 - - - 1.5233 - 2.393 0.486 - 155.9 1 2 0 0.0023 13 0 0 0 7.35E+06 3.83E+06 - - - 6.3235 0.9992 221125_WJC_METTL3_EV_vs_WT_F08.21211.21211.4 0.000143 13/144 K.K[136.11]VEHEISEGNVATAAAAALASAATK[136.11].A sp|Q92922|SMRC1_HUMAN 1 2425.2784 3.32 122347 21211 4 2425.278217 607.3269 SWI\SNF complex subunit SMARCC1 OS=Homo sapiens OX=9606 GN=SMARCC1 PE=1 SV=3 5.5 3465.1 - 150212 - - - -0.0618 - 2.741 0.301 - 101.9 1 2 0 -0.0001 25 0 0 0 5.27E+07 1.59E+07 - - - 2.1666 1 221125_WJC_METTL3_EV_vs_WT_F08.21215.21215.4 1.90E-08 22/144 K.KVEHEISEGNVATAAAAALASAATK.A sp|Q92922|SMRC1_HUMAN 1 2409.25 3.32 122349 21215 4 2409.254849 603.3198 SWI\SNF complex subunit SMARCC1 OS=Homo sapiens OX=9606 GN=SMARCC1 PE=1 SV=3 5.5 3465.7 - 677591 - - - 2.0264 - 4.155 0.55 - 409.5 1 2 0 0.0049 25 0 0 0 5.27E+07 1.59E+07 - - - 4.465 1 221125_WJC_METTL3_EV_vs_WT_F08.21217.21217.4 8.52E-17 39/210 K.LAQQQASAAAAAAAATAAATAATTTSAGVSHQNPSK[136.11].N "sp|O60907|TBL1X_HUMAN,tr|A0A804HJZ5|A0A804HJZ5_HUMAN,tr|A0A2R8YFW3|A0A2R8YFW3_HUMAN" 3 3273.6429 1.75 122351 21217 4 3273.647218 819.418 F-box-like\WD repeat-containing protein TBL1X OS=Homo sapiens OX=9606 GN=TBL1X PE=1 SV=3 8.76 3465.9 - 735793 - - - 1.316 - 7.045 0.704 - 1055.5 1 2 0 0.0043 36 0 0 0 1.56E+08 8.90E+07 - - - 5.9279 1 221125_WJC_METTL3_EV_vs_WT_F08.21221.21221.4 4.28E-11 24/204 R.YGPQYGHPPPPPPPPEYGPHADSPVLMVYGLDQSK.M "sp|P14866|HNRPL_HUMAN,tr|A0A3B3ITJ4|A0A3B3ITJ4_HUMAN,tr|M0QXS5|M0QXS5_HUMAN" 3 3783.8032 0.13 122353 21221 4 3783.813009 946.9581 Heterogeneous nuclear ribonucleoprotein L OS=Homo sapiens OX=9606 GN=HNRNPL PE=1 SV=2 5.21 3466.5 - 359271 - - - 2.6006 - 4.418 0.625 - 313.7 1 2 0 0.0098 35 0 0 0 1.04E+07 8.06E+07 - - - 5.1037 0.9998 221125_WJC_METTL3_EV_vs_WT_F08.21237.21237.2 0.000137 22-Nov K.WELLQQVDTSTR.T sp|P04264|K2C1_HUMAN 1 1474.7416 4.07 122365 21237 2 1474.743408 738.3781 "Keratin, type II cytoskeletal 1 OS=Homo sapiens OX=9606 GN=KRT1 PE=1 SV=6" 4.37 3468.6 - 326342 - - - 1.2212 - 2.455 0.511 - 461.3 1 2 0 0.0018 12 0 0 0 2.18E+07 5.34E+06 - - - 5.1778 0.9997 221125_WJC_METTL3_EV_vs_WT_F08.21242.21242.4 2.31E-05 13/102 R.KKEDLQEVDGEIEAVLQK.K "sp|O15381|NVL_HUMAN,tr|E9PH71|E9PH71_HUMAN,tr|C9J6P7|C9J6P7_HUMAN,tr|E7EWK7|E7EWK7_HUMAN,tr|C9JP83|C9JP83_HUMAN" 5 2070.0845 1.63 122368 21242 4 2070.090665 518.5284 Nuclear valosin-containing protein-like OS=Homo sapiens OX=9606 GN=NVL PE=1 SV=1 4.36 3469.3 - 221399 - - - 2.995 - 2.295 0.544 - 66.4 1 2 1 0.0062 18 0 0 0 7.85E+06 4.81E+06 - - - 4.2438 0.9921 221125_WJC_METTL3_EV_vs_WT_F08.21243.21243.3 0.000215 Nov-48 D.LEIESLLNQQSTK[136.11].E "sp|Q86U44|MTA70_HUMAN,tr|F5H6D8|F5H6D8_HUMAN,tr|H0YFV6|H0YFV6_HUMAN,tr|B4DTN4|B4DTN4_HUMAN" 4 1509.813 0 122369 21243 3 1509.814835 504.2783 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 4.53 3469.4 - 249643 - - - 1.2233 - 2.109 0.459 - 198.7 1 1 0 0.0018 13 0 0 0 1.67E+04 4.42E+06 - - - 5.6801 0.9955 221125_WJC_METTL3_EV_vs_WT_F08.21244.21244.3 1.95E-07 13/92 K.NQSQGYNQWQQGQFWGQKPWSQHY.H "sp|Q00839|HNRPU_HUMAN,tr|A0A1W2PPL4|A0A1W2PPL4_HUMAN,tr|Q5RI18|Q5RI18_HUMAN,tr|A0A1W2PP35|A0A1W2PP35_HUMAN,tr|A0A1W2PPH7|A0A1W2PPH7_HUMAN,tr|A0A1X7SBS1|A0A1X7SBS1_HUMAN" 6 3009.3331 1.09 122370 21244 3 3009.341493 1004.1183 Heterogeneous nuclear ribonucleoprotein U OS=Homo sapiens OX=9606 GN=HNRNPU PE=1 SV=6 8.5 3469.5 - 325572 - - - 2.7767 - 2.668 0.621 - 114.1 1 1 0 0.0084 24 0 0 0 1.29E+07 1.18E+07 - - - 7.7405 0.9999 221125_WJC_METTL3_EV_vs_WT_F08.21249.21249.3 3.16E-05 Oct-64 R.VEAVNMAEGIIHDTETK[136.11].M "sp|P38646|GRP75_HUMAN,tr|A0A7I2V2S7|A0A7I2V2S7_HUMAN,tr|A0A7I2V2G2|A0A7I2V2G2_HUMAN,tr|A0A7I2V3F7|A0A7I2V3F7_HUMAN,tr|A0A7I2YQB2|A0A7I2YQB2_HUMAN,tr|D6RCD7|D6RCD7_HUMAN" 6 1863.9128 0.25 122373 21249 3 1863.917293 622.3115 "Stress-70 protein, mitochondrial OS=Homo sapiens OX=9606 GN=HSPA9 PE=1 SV=2" 4.4 3470.2 - 224743 - - - 2.4223 - 2.232 0.467 - 112 1 2 0 0.0045 17 0 0 0 1.05E+06 4.20E+06 - - - 5.7737 1 221125_WJC_METTL3_EV_vs_WT_F08.21251.21251.4 1.42E-11 24/216 K.GDFFPPER[166.11]PQQLPHGLGGIGMGLGPGGQPIDANHLNK[136.11].G "sp|P52272|HNRPM_HUMAN,tr|M0R019|M0R019_HUMAN,tr|M0R0N3|M0R0N3_HUMAN,tr|A0A087X0X3|A0A087X0X3_HUMAN,tr|M0QZM1|M0QZM1_HUMAN" 5 3835.9336 2.16 122375 21251 4 3835.942117 959.9907 Heterogeneous nuclear ribonucleoprotein M OS=Homo sapiens OX=9606 GN=HNRNPM PE=1 SV=3 6 3470.5 - 323570 - - - 2.2289 - 3.798 0.569 - 175.2 1 2 0 0.0086 37 0 0 0 7.44E+07 3.45E+07 - - - 4.5674 0.9999 221125_WJC_METTL3_EV_vs_WT_F08.21254.21254.4 6.88E-10 25/216 K.GDFFPPERPQQLPHGLGGIGMGLGPGGQPIDANHLNK.G "sp|P52272|HNRPM_HUMAN,tr|M0R019|M0R019_HUMAN,tr|M0R0N3|M0R0N3_HUMAN,tr|A0A087X0X3|A0A087X0X3_HUMAN,tr|M0QZM1|M0QZM1_HUMAN" 5 3817.9111 2.17 122376 21254 4 3817.924368 955.4851 Heterogeneous nuclear ribonucleoprotein M OS=Homo sapiens OX=9606 GN=HNRNPM PE=1 SV=3 6 3470.9 - 719690 - - - 3.476 - 4.652 0.573 - 221.8 1 2 0 0.0133 37 0 0 0 5.92E+07 2.73E+07 - - - 4.6604 0.9996 221125_WJC_METTL3_EV_vs_WT_F08.21256.21256.3 0.000285 11/124 K.VGGTNLGAPGAFGQSPFSQPPAPPHQNTFPPR.S sp|Q96I24|FUBP3_HUMAN 1 3227.5901 2.66 122377 21256 3 3227.595702 1076.8706 Far upstream element-binding protein 3 OS=Homo sapiens OX=9606 GN=FUBP3 PE=1 SV=2 9.73 3471.1 - 172257 - - - 1.7419 - 1.979 0.395 - 66 1 2 0 0.0056 32 0 0 0 1.60E+07 6.00E+06 - - - 4.5127 1 221125_WJC_METTL3_EV_vs_WT_F08.21264.21264.3 4.58E-11 20/96 K.KVEHEISEGNVATAAAAALASAATK.A sp|Q92922|SMRC1_HUMAN 1 2409.25 6.88 122382 21264 3 2409.254913 804.0906 SWI\SNF complex subunit SMARCC1 OS=Homo sapiens OX=9606 GN=SMARCC1 PE=1 SV=3 5.5 3472.1 - 412084 - - - 2.0529 - 4.244 0.61 - 470.7 1 2 0 0.0049 25 0 0 0 1.31E+07 1.91E+06 - - - 8.6651 0.8838 221125_WJC_METTL3_EV_vs_WT_F08.21272.21272.4 0.145 5/108 K.K[136.11]AQDEGLLSDVVPFK[136.11]VPGK[136.11].D "sp|P55084|ECHB_HUMAN,tr|F5GZQ3|F5GZQ3_HUMAN" 2 2050.1525 0.8 122387 21272 4 2050.158857 513.5454 "Trifunctional enzyme subunit beta, mitochondrial OS=Homo sapiens OX=9606 GN=HADHB PE=1 SV=3" 6.12 3473.3 - 100201 - - - 3.1046 - 1.289 0.241 - 16.7 2 2 1 0.0064 19 0 0 0 1.52E+06 1.91E+06 - - - 1.1783 0.9994 221125_WJC_METTL3_EV_vs_WT_F08.21276.21276.2 0.00434 16-Sep K.LLQDFFNGK[136.11].E "sp|P54652|HSP72_HUMAN,sp|P11142|HSP7C_HUMAN,sp|P17066|HSP76_HUMAN,tr|E9PNE6|E9PNE6_HUMAN,tr|A8K7Q2|A8K7Q2_HUMAN,tr|E9PKE3|E9PKE3_HUMAN,tr|E9PN89|E9PN89_HUMAN" 7 1088.5746 0.19 122388 21276 2 1088.576311 545.2946 Heat shock-related 70 kDa protein 2 OS=Homo sapiens OX=9606 GN=HSPA2 PE=1 SV=1 5.84 3473.9 - 330273 - - - 1.5764 - 1.899 0.347 - 142.6 1 2 0 0.0017 9 0 0 0 2.32E+06 1.19E+07 - - - 3.4588 0.9971 221125_WJC_METTL3_EV_vs_WT_F08.21278.21278.3 3.69E-09 20/84 H.SALSSASTSSHNLQSIFNIGSR.G "sp|P43243|MATR3_HUMAN,tr|A8MXP9|A8MXP9_HUMAN,tr|D6R991|D6R991_HUMAN,tr|D6REK4|D6REK4_HUMAN,tr|A0A0R4J2E8|A0A0R4J2E8_HUMAN,tr|D6RCM3|D6RCM3_HUMAN,tr|D6R8Z5|D6R8Z5_HUMAN,tr|D6REM6|D6REM6_HUMAN" 8 2263.1193 2.26 122390 21278 3 2263.124401 755.3804 Matrin-3 OS=Homo sapiens OX=9606 GN=MATR3 PE=1 SV=2 9.49 3474.2 - 487900 - - - 2.2597 - 3.59 0.568 - 529.6 1 1 0 0.0051 22 0 0 0 1.45E+07 6.43E+06 - - - 7.9015 1 221125_WJC_METTL3_EV_vs_WT_F08.21288.21288.3 2.66E-12 19/144 K.VGGTKPAGGDFGEVLNSAANASATTTEPLPEKTQESL.- "sp|P55327|TPD52_HUMAN,tr|E5RK35|E5RK35_HUMAN" 2 3643.7853 2.53 122395 21288 3 3643.78641 1215.6024 Tumor protein D52 OS=Homo sapiens OX=9606 GN=TPD52 PE=1 SV=2 4.25 3475.5 - 342516 - - - 0.2964 - 4.261 0.692 - 148 1 2 1 0.0011 37 0 0 0 8.11E+06 3.21E+06 - - - 9.5896 0.9973 221125_WJC_METTL3_EV_vs_WT_F08.21291.21291.2 0.0102 16-May K.LLQDFFNGK.E "sp|P54652|HSP72_HUMAN,sp|P11142|HSP7C_HUMAN,sp|P17066|HSP76_HUMAN,tr|E9PNE6|E9PNE6_HUMAN,tr|A8K7Q2|A8K7Q2_HUMAN,tr|E9PKE3|E9PKE3_HUMAN,tr|E9PN89|E9PN89_HUMAN" 7 1080.5604 0.19 122397 21291 2 1080.559181 541.2875 Heat shock-related 70 kDa protein 2 OS=Homo sapiens OX=9606 GN=HSPA2 PE=1 SV=1 5.84 3475.8 - 72698.8 - - - -1.1235 - 1.052 0.346 - 41.3 1 2 0 -0.0012 9 0 0 0 2.26E+06 1.19E+07 - - - 1.7428 0.9998 221125_WJC_METTL3_EV_vs_WT_F08.21304.21304.4 1.65E-07 19/150 R.TGHILHPEYLQPLPSTPVSPIELDAK.K sp|Q96F45|ZN503_HUMAN 1 2851.512 2.13 122404 21304 4 2851.51926 713.8853 Zinc finger protein 503 OS=Homo sapiens OX=9606 GN=ZNF503 PE=1 SV=1 5.26 3477.5 - 300433 - - - 2.5474 - 3.14 0.444 - 106 1 2 0 0.0073 26 0 0 0 5.03E+06 2.36E+06 - - - 3.4495 0.9971 221125_WJC_METTL3_EV_vs_WT_F08.21306.21306.3 2.14E-08 28/80 R.K[136.11]HAASDVDLEIESLLNQQSTK[136.11].E "sp|Q86U44|MTA70_HUMAN,tr|F5H6D8|F5H6D8_HUMAN,tr|H0YFV6|H0YFV6_HUMAN,tr|B4DTN4|B4DTN4_HUMAN" 4 2341.2096 0.19 122405 21306 3 2342.202645 781.4105 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 4.75 3477.7 - 1.45E+06 - - - 424.1508 - 4.764 0.57 - 1274.9 1 2 0 0.993 21 0 0 0 1.25E+07 6.43E+07 - - - 8.3625 0.9734 221125_WJC_METTL3_EV_vs_WT_F08.21307.21307.4 0.00203 14/120 R.K[136.11]IELFGR[166.11]PHNVQPNWITLGNQ.L sp|Q86U44|MTA70_HUMAN 1 2478.3251 0 122406 21307 4 2478.328891 620.5885 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 8.75 3477.8 - 815882 - - - 1.5369 - 2.81 0.375 - 107 1 1 0 0.0038 21 0 0 0 2.91E+05 6.28E+07 - - - 2.8306 0.9973 221125_WJC_METTL3_EV_vs_WT_F08.21329.21329.3 1.31E-06 15/52 Q.LDGIHLLDPDVVAR[166.11].F sp|Q86U44|MTA70_HUMAN 1 1541.8441 0.01 122418 21329 3 1541.842927 514.9553 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 4.41 3480.6 - 244469 - - - -0.7686 - 2.826 0.485 - 342.9 1 1 0 -0.0012 14 0 0 0 2.31E+05 1.94E+07 - - - 6.7078 1 221125_WJC_METTL3_EV_vs_WT_F08.21337.21337.4 1.23E-06 18/126 K.HTDESLGDC[160.03]SFLNTC[160.03]FHMDTC[160.03]K[136.11].Y "sp|Q86U44|MTA70_HUMAN,tr|H0YFV6|H0YFV6_HUMAN" 2 2682.0698 0.02 122424 21337 4 2682.074748 671.5247 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 4.64 3481.7 - 273276 - - - 1.8284 - 3.887 0.695 - 342.8 1 2 0 0.0049 22 0 0 0 2.05E+05 1.23E+07 - - - 5.7181 0.9995 221125_WJC_METTL3_EV_vs_WT_F08.21347.21347.3 1.32E-07 13/76 K.GNPQGFNQGLDC[160.03]DVIVAEVR[166.11].S sp|Q86U44|MTA70_HUMAN 1 2197.0461 0.01 122430 21347 3 2198.050211 733.356 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 4.03 3483 - 407959 - - - 457.0113 - 2.669 0.577 - 179.3 1 2 0 1.0041 20 0 0 0 5.39E+06 4.97E+08 - - - 7.0765 1 221125_WJC_METTL3_EV_vs_WT_F08.21358.21358.2 3.08E-09 Dec-38 K.GNPQGFNQGLDC[160.03]DVIVAEVR[166.11].S sp|Q86U44|MTA70_HUMAN 1 2197.0461 0.001 122437 21358 2 2198.039519 1099.5303 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 4.03 3484.5 - 174189 - - - 452.1448 - 2.559 0.649 - 329.6 1 2 0 0.9934 20 0 0 0 0.00E+00 8.75E+07 - - - 5.8327 1 221125_WJC_METTL3_EV_vs_WT_F08.21386.21386.4 2.60E-08 23/180 M.PTGDFDSK[136.11]PSWADQVEEEGEDDK[136.11]C[160.03]VTSELLK[136.11].G "sp|O75821|EIF3G_HUMAN,tr|K7ER90|K7ER90_HUMAN,tr|K7EL20|K7EL20_HUMAN,tr|K7ENH0|K7ENH0_HUMAN,tr|K7ENA8|K7ENA8_HUMAN,tr|K7EL60|K7EL60_HUMAN" 6 3534.6047 0.86 122450 21386 4 3534.599176 884.6584 Eukaryotic translation initiation factor 3 subunit G OS=Homo sapiens OX=9606 GN=EIF3G PE=1 SV=2 3.93 3488.6 - 488789 - - - -1.5501 - 4.348 0.701 - 304.8 1 2 1 -0.0055 31 0 0 0 7.42E+06 8.68E+06 - - - 5.7727 1 221125_WJC_METTL3_EV_vs_WT_F08.21395.21395.4 1.06E-08 18/186 K.YGYNAGEATHHAVDSAVNVGVTAYNINNIGIK.A sp|Q8N0X7|SPART_HUMAN 1 3331.6222 0.72 122455 21395 4 3331.619806 833.9128 Spartin OS=Homo sapiens OX=9606 GN=SPART PE=1 SV=1 5.99 3489.7 - 343030 - - - -0.709 - 2.495 0.609 - 102.8 1 2 0 -0.0024 32 0 0 0 3.25E+06 4.51E+06 - - - 4.8021 1 221125_WJC_METTL3_EV_vs_WT_F08.21401.21401.3 6.68E-12 23/124 R.GGGGSFGYSYGGGSGGGFSASSLGGGFGGGSR.G sp|P35527|K1C9_HUMAN 1 2704.1538 999 122459 21401 3 2704.148956 902.3919 "Keratin, type I cytoskeletal 9 OS=Homo sapiens OX=9606 GN=KRT9 PE=1 SV=3" 8.59 3490.5 - 1.16E+06 - - - -1.8043 - 3.926 0.677 - 274.4 1 2 0 -0.0049 32 0 0 0 4.38E+07 0.00E+00 - - - 9.2329 1 221125_WJC_METTL3_EV_vs_WT_F08.21413.21413.2 8.51E-07 27/40 R.K[136.11]HAASDVDLEIESLLNQQSTK[136.11].E "sp|Q86U44|MTA70_HUMAN,tr|F5H6D8|F5H6D8_HUMAN,tr|H0YFV6|H0YFV6_HUMAN,tr|B4DTN4|B4DTN4_HUMAN" 4 2341.2096 0.01 122467 21413 2 2342.20479 1171.6121 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 4.75 3492 - 3.52E+06 - - - 425.067 - 5.043 0.643 - 1830.5 1 2 0 0.9952 21 0 0 0 3.31E+07 5.84E+09 - - - 7.4556 0.9775 221125_WJC_METTL3_EV_vs_WT_F08.21423.21423.2 0.195 26-Sep R.ELLDTSFEDLSK[136.11]PK.R sp|P78345|RPP38_HUMAN 1 1628.8389 - 122473 21423 2 1628.839436 815.4267 Ribonuclease P protein subunit p38 OS=Homo sapiens OX=9606 GN=RPP38 PE=1 SV=2 4.32 3493.4 - 1.10E+06 - - - 0.3487 - 1.556 0.013 - 160.4 2 2 0 0.0006 14 0 0 0 - - - - - 0.1118 0.999 221125_WJC_METTL3_EV_vs_WT_F08.21457.21457.3 0.000132 17/80 R.KHAASDVDLEIESLLNQQSTK.E "sp|Q86U44|MTA70_HUMAN,tr|F5H6D8|F5H6D8_HUMAN,tr|H0YFV6|H0YFV6_HUMAN,tr|B4DTN4|B4DTN4_HUMAN" 4 2325.1812 0.01 122486 21457 3 2326.18041 776.0677 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 4.75 3497.8 - 9.81E+06 - - - 429.7261 - 3.796 0.489 - 370.3 1 2 0 0.9992 21 0 0 0 5.01E+08 5.72E+10 - - - 6.9132 0.8853 221125_WJC_METTL3_EV_vs_WT_F08.21467.21467.2 5.33E-06 16/22 L.EIESLLNQQSTK[136.11].E "sp|Q86U44|MTA70_HUMAN,tr|F5H6D8|F5H6D8_HUMAN,tr|H0YFV6|H0YFV6_HUMAN,tr|B4DTN4|B4DTN4_HUMAN" 4 1396.7289 0.04 122489 21467 2 1396.722402 699.3717 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 4.53 3499.1 - 2.49E+06 - - - -4.6695 - 2.893 0.372 - 825.4 1 1 0 -0.0065 12 0 0 0 6.04E+06 1.41E+08 - - - 4.5816 1 221125_WJC_METTL3_EV_vs_WT_F08.21479.21479.2 7.46E-11 26/40 R.K[136.11]HAASDVDLEIESLLNQQSTK.E "sp|Q86U44|MTA70_HUMAN,tr|F5H6D8|F5H6D8_HUMAN,tr|H0YFV6|H0YFV6_HUMAN,tr|B4DTN4|B4DTN4_HUMAN" 4 2333.1954 - 122491 21479 2 2334.186501 1167.605 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 4.75 3501 - 6.01E+06 - - - 424.7745 - 4.59 0.655 - 1275.8 1 2 0 0.9911 21 0 0 0 - - - - - 7.3142 1 221125_WJC_METTL3_EV_vs_WT_F08.21536.21536.4 1.50E-20 41/156 R.R[166.11]QLLAQQLGAESADSIGAVLNSK[136.11]DEQR[166.11].E "sp|Q9HCE5|MET14_HUMAN,tr|A0A0D9SFW0|A0A0D9SFW0_HUMAN,tr|A0A0D9SF88|A0A0D9SF88_HUMAN" 3 2924.531 0.02 122501 21536 4 2925.523793 732.14 N6-adenosine-methyltransferase non-catalytic subunit OS=Homo sapiens OX=9606 GN=METTL14 PE=1 SV=2 4.78 3509.5 - 3.72E+06 - - - 339.4702 - 6.557 0.697 - 1623.1 1 2 1 0.9928 27 0 0 0 2.76E+06 1.65E+08 - - - 5.6061 0.9371 221125_WJC_METTL3_EV_vs_WT_F08.21543.21543.2 0.00111 20-Dec E.IESLLNQQSTK[136.11].E "sp|Q86U44|MTA70_HUMAN,tr|F5H6D8|F5H6D8_HUMAN,tr|H0YFV6|H0YFV6_HUMAN,tr|B4DTN4|B4DTN4_HUMAN" 4 1267.6863 0.001 122502 21543 2 1267.682162 634.8504 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 6 3510.6 - 1.30E+06 - - - -3.2887 - 2.462 0.351 - 547.3 1 1 0 -0.0042 11 0 0 0 0.00E+00 5.64E+07 - - - 4.0695 0.9999 221125_WJC_METTL3_EV_vs_WT_F08.21554.21554.2 5.01E-07 14/22 K.SLNNQFASFIDK.V sp|P04264|K2C1_HUMAN 1 1382.683 3.07 122504 21554 2 1382.682329 692.3488 "Keratin, type II cytoskeletal 1 OS=Homo sapiens OX=9606 GN=KRT1 PE=1 SV=6" 5.55 3512.2 - 1.53E+06 - - - -0.507 - 2.384 0.579 - 654.3 1 2 0 -0.0007 12 0 0 0 5.89E+07 1.92E+07 - - - 5.6032 0.993 221125_WJC_METTL3_EV_vs_WT_F08.21615.21615.3 3.03E-08 17/64 L.GNQLDGIHLLDPDVVAR[166.11].F sp|Q86U44|MTA70_HUMAN 1 1840.9671 0 122511 21615 3 1840.960354 614.663 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 4.41 3521.6 - 3.62E+06 - - - -3.6541 - 3.289 0.585 - 286.2 1 1 0 -0.0067 17 0 0 0 1.16E+06 2.60E+08 - - - 8.0681 0.8581 221125_WJC_METTL3_EV_vs_WT_F08.21618.21618.3 0.00339 15/72 R.IQEIIEQLDVTTSEYEK[136.11]EK[136.11].L "sp|P10809|CH60_HUMAN,tr|A0A7I2V2X6|A0A7I2V2X6_HUMAN,tr|A0A7I2YQK6|A0A7I2YQK6_HUMAN,tr|A0A7I2V599|A0A7I2V599_HUMAN" 4 2310.1813 0.65 122512 21618 3 2311.171324 771.0677 "60 kDa heat shock protein, mitochondrial OS=Homo sapiens OX=9606 GN=HSPD1 PE=1 SV=2" 4.14 3522 - 1.72E+06 - - - 428.5313 - 3.142 0.445 - 256.2 1 2 1 0.99 19 0 0 0 8.92E+07 1.38E+08 - - - 6.0398 1 221125_WJC_METTL3_EV_vs_WT_F08.21642.21642.3 2.78E-10 23/72 R.IQEIIEQLDVTTSEYEKEK.L "sp|P10809|CH60_HUMAN,tr|A0A7I2V2X6|A0A7I2V2X6_HUMAN,tr|A0A7I2YQK6|A0A7I2YQK6_HUMAN,tr|A0A7I2V599|A0A7I2V599_HUMAN" 4 2294.1529 0.72 122521 21642 3 2294.149334 765.7249 "60 kDa heat shock protein, mitochondrial OS=Homo sapiens OX=9606 GN=HSPD1 PE=1 SV=2" 4.14 3525.1 - 3.30E+06 - - - -1.5714 - 3.98 0.606 - 691.5 1 2 1 -0.0036 19 0 0 0 8.33E+07 1.15E+08 - - - 8.6888 0.9999 221125_WJC_METTL3_EV_vs_WT_F08.21682.21682.4 3.84E-10 34/252 K.VVGSAVGSGSITSNIVASNSLPPATIAPPKPASWADIASKPAK.Q sp|Q9Y5A9|YTHD2_HUMAN 1 4113.211 1.57 122536 21682 4 4113.192316 1029.31 YTH domain-containing family protein 2 OS=Homo sapiens OX=9606 GN=YTHDF2 PE=1 SV=2 9.7 3530.4 - 3.01E+06 - - - -4.5449 - 5.283 0.582 - 285.2 1 2 0 -0.0187 43 0 0 0 1.92E+08 1.22E+08 - - - 4.7603 0.9982 221125_WJC_METTL3_EV_vs_WT_F08.21683.21683.3 0.00152 16/80 R.KHAASDVDLEIESLLNQQSTK.E "sp|Q86U44|MTA70_HUMAN,tr|F5H6D8|F5H6D8_HUMAN,tr|H0YFV6|H0YFV6_HUMAN,tr|B4DTN4|B4DTN4_HUMAN" 4 2325.1812 0.01 122537 21683 3 2326.182354 776.0677 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 4.75 3530.5 - 1.25E+06 - - - 430.5621 - 3.178 0.414 - 371 1 2 0 1.0011 21 0 0 0 7.42E+08 7.54E+10 - - - 5.6504 0.8926 221125_WJC_METTL3_EV_vs_WT_F08.21690.21690.2 0.437 12-Jul L.LNQQSTK[136.11].E "sp|Q86U44|MTA70_HUMAN,tr|F5H6D8|F5H6D8_HUMAN,tr|H0YFV6|H0YFV6_HUMAN,tr|B4DTN4|B4DTN4_HUMAN" 4 825.4436 0.001 122541 21690 2 825.441373 413.7291 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 8.75 3531.4 - 511435 - - - -2.6749 - 1.445 0.364 - 112.7 1 1 0 -0.0022 7 0 0 0 0.00E+00 7.81E+07 - - - 2.8952 1 221125_WJC_METTL3_EV_vs_WT_F08.21701.21701.2 1.07E-08 24/40 R.K[136.11]HAASDVDLEIESLLNQQSTK[136.11].E "sp|Q86U44|MTA70_HUMAN,tr|F5H6D8|F5H6D8_HUMAN,tr|H0YFV6|H0YFV6_HUMAN,tr|B4DTN4|B4DTN4_HUMAN" 4 2341.2096 0 122544 21701 2 2342.206927 1171.6121 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 4.75 3533 - 2.09E+06 - - - 425.9798 - 4.927 0.661 - 1378.6 1 2 0 0.9973 21 0 0 0 4.88E+06 3.40E+09 - - - 7.5307 1 221125_WJC_METTL3_EV_vs_WT_F08.21711.21711.3 5.90E-18 29/112 K.GSGDPSSSSSSGNPLVYLDVDANGKPLGR.V "sp|P30405|PPIF_HUMAN,tr|R4GN99|R4GN99_HUMAN" 2 2832.3526 1.15 122549 21711 3 2832.350103 945.1248 "Peptidyl-prolyl cis-trans isomerase F, mitochondrial OS=Homo sapiens OX=9606 GN=PPIF PE=1 SV=1" 4.43 3534.2 - 474085 - - - -0.8798 - 5.019 0.798 - 519.5 1 2 0 -0.0025 29 0 0 0 2.24E+07 1.95E+07 - - - 11.1477 1 221125_WJC_METTL3_EV_vs_WT_F08.21715.21715.4 1.82E-12 27/276 K.SAAPAPISASC[160.03]PEPPIGSAVPTSSASIPVTSSVSDPGVGSISPASPK.L "sp|Q8WWM7|ATX2L_HUMAN,tr|H3BUF6|H3BUF6_HUMAN" 2 4371.1792 2.93 122551 21715 4 4371.178374 1093.8021 Ataxin-2-like protein OS=Homo sapiens OX=9606 GN=ATXN2L PE=1 SV=2 4.37 3534.7 - 1.26E+06 - - - -0.1839 - 5.106 0.662 - 183.6 1 2 0 -0.0008 47 0 0 0 3.19E+07 1.09E+07 - - - 5.444 0.9982 221125_WJC_METTL3_EV_vs_WT_F08.21719.21719.4 0.0081 Sep-84 R.STSHK[136.11]PDEIYGMIER[166.11].L sp|Q86U44|MTA70_HUMAN 1 1779.8581 0 122555 21719 4 1779.853892 445.9718 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 5.42 3535.2 - 230229 - - - -2.3384 - 1.751 0.305 - 37.8 1 2 0 -0.0042 15 0 0 0 4.51E+04 1.23E+07 - - - 2.08 1 221125_WJC_METTL3_EV_vs_WT_F08.21722.21722.4 1.32E-08 18/216 K.GDFFPPERPQQLPHGLGGIGMGLGPGGQPIDANHLNK.G "sp|P52272|HNRPM_HUMAN,tr|M0R019|M0R019_HUMAN,tr|M0R0N3|M0R0N3_HUMAN,tr|A0A087X0X3|A0A087X0X3_HUMAN,tr|M0QZM1|M0QZM1_HUMAN" 5 3817.9111 3.02 122556 21722 4 3817.904357 955.4851 Heterogeneous nuclear ribonucleoprotein M OS=Homo sapiens OX=9606 GN=HNRNPM PE=1 SV=3 6 3535.6 - 530502 - - - -1.7654 - 3.948 0.492 - 115.4 1 2 0 -0.0067 37 0 0 0 1.74E+07 5.74E+06 - - - 3.9091 0.9979 221125_WJC_METTL3_EV_vs_WT_F08.21725.21725.3 0.0202 Dec-44 K.IEEIKDFLLTAR.R "sp|P63173|RL38_HUMAN,tr|J3KT73|J3KT73_HUMAN,tr|J3QL01|J3QL01_HUMAN,tr|J3KSP2|J3KSP2_HUMAN" 4 1446.8082 1.78 122559 21725 3 1446.807095 483.2767 60S ribosomal protein L38 OS=Homo sapiens OX=9606 GN=RPL38 PE=1 SV=2 4.68 3536 - 386118 - - - -0.7845 - 2.107 0.294 - 132.8 1 2 1 -0.0011 12 0 0 0 9.38E+06 5.25E+06 - - - 3.8833 0.9999 221125_WJC_METTL3_EV_vs_WT_F08.21732.21732.4 5.11E-06 27/138 K.QISNLQQSISDAEQRGENALKDAK.N sp|P04264|K2C1_HUMAN 1 2642.326 26.88 122562 21732 4 2642.325454 661.5888 "Keratin, type II cytoskeletal 1 OS=Homo sapiens OX=9606 GN=KRT1 PE=1 SV=6" 4.78 3536.8 - 1.00E+06 - - - -0.2013 - 3.378 0.507 - 469.9 1 2 2 -0.0005 24 0 0 0 8.00E+07 2.98E+06 - - - 4.0295 1 221125_WJC_METTL3_EV_vs_WT_F08.21734.21734.4 4.70E-10 18/204 K.GISEDSHLESLQDVGQSAAPTFMISPETVTGTGK[136.11]K[136.11].C "sp|P27816|MAP4_HUMAN,tr|E7EVA0|E7EVA0_HUMAN,tr|A0A804HKE7|A0A804HKE7_HUMAN" 3 3632.7851 0.18 122563 21734 4 3632.775186 909.2035 Microtubule-associated protein 4 OS=Homo sapiens OX=9606 GN=MAP4 PE=1 SV=3 4.5 3537 - 493972 - - - -2.7213 - 3.248 0.666 - 122 1 2 0 -0.0099 35 0 0 0 1.63E+06 9.11E+06 - - - 5.3694 0.9992 221125_WJC_METTL3_EV_vs_WT_F08.21736.21736.4 2.75E-11 17/276 K.SAAPAPISASC[160.03]PEPPIGSAVPTSSASIPVTSSVSDPGVGSISPASPK[136.11].L "sp|Q8WWM7|ATX2L_HUMAN,tr|H3BUF6|H3BUF6_HUMAN" 2 4379.1934 2.93 122565 21736 4 4380.18644 1095.8056 Ataxin-2-like protein OS=Homo sapiens OX=9606 GN=ATXN2L PE=1 SV=2 4.37 3537.3 - 479838 - - - 226.7682 - 3.908 0.648 - 77.6 1 2 0 0.9931 47 0 0 0 3.19E+07 1.09E+07 - - - 4.9724 0.996 221125_WJC_METTL3_EV_vs_WT_F08.21745.21745.4 6.03E-09 20/126 R.K[136.11]HAASDVDLEIESLLNQQSTK[136.11]E.Q "sp|Q86U44|MTA70_HUMAN,tr|F5H6D8|F5H6D8_HUMAN,tr|H0YFV6|H0YFV6_HUMAN,tr|B4DTN4|B4DTN4_HUMAN" 4 2470.2522 0.33 122569 21745 4 2470.252365 618.5703 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 4.67 3538.6 - 417638 - - - 0.0619 - 3.504 0.495 - 236.6 1 1 0 0.0002 22 0 0 0 5.10E+06 1.55E+07 - - - 3.9447 1 221125_WJC_METTL3_EV_vs_WT_F08.21760.21760.4 2.65E-18 22/234 K.TAQALAQLAAQHSQSGSTTTSSWDMGSTTQSPSLVQYDLK.N "sp|Q14157|UBP2L_HUMAN,tr|F8W726|F8W726_HUMAN" 2 4181.9811 1.94 122574 21760 4 4181.98288 1046.5026 Ubiquitin-associated protein 2-like OS=Homo sapiens OX=9606 GN=UBAP2L PE=1 SV=2 5.18 3540.6 - 669479 - - - 0.4146 - 4.341 0.739 - 186 1 2 0 0.0017 40 0 0 0 5.52E+07 2.85E+07 - - - 6.0816 0.9999 221125_WJC_METTL3_EV_vs_WT_F08.21763.21763.4 4.00E-06 18/126 K.VQALEEANNDLENKIQDWYDKK.G sp|P35527|K1C9_HUMAN 1 2662.2875 253.91 122575 21763 4 2662.291281 666.5791 "Keratin, type I cytoskeletal 9 OS=Homo sapiens OX=9606 GN=KRT9 PE=1 SV=3" 4.3 3541 - 362437 - - - 1.4296 - 3.498 0.56 - 121.2 1 2 1 0.0038 22 0 0 0 4.00E+07 1.58E+05 - - - 4.5089 1 221125_WJC_METTL3_EV_vs_WT_F08.21775.21775.3 1.45E-05 Aug-52 K.K[136.11]GPGEVAGTVTGQK[136.11].R "sp|Q86U44|MTA70_HUMAN,tr|F5H6D8|F5H6D8_HUMAN,tr|H0YFV6|H0YFV6_HUMAN,tr|B4DTN4|B4DTN4_HUMAN" 4 1343.738 0 122580 21775 3 1343.737908 448.9199 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 8.59 3542.7 - 129795 - - - -0.0528 - 1.998 0.539 - 77.7 1 2 0 -0.0001 14 0 0 0 2.02E+04 1.20E+07 - - - 6.3887 0.9711 221125_WJC_METTL3_EV_vs_WT_F08.21781.21781.3 0.0168 Sep-92 K.QISNLQQSISDAEQRGENALKDAK.N sp|P04264|K2C1_HUMAN 1 2642.326 999 122582 21781 3 2642.334499 881.7826 "Keratin, type II cytoskeletal 1 OS=Homo sapiens OX=9606 GN=KRT1 PE=1 SV=6" 4.78 3543.6 - 137524 - - - 3.2218 - 1.773 0.286 - 58.6 1 2 2 0.0085 24 0 0 0 6.11E+06 0.00E+00 - - - 3.0563 0.9997 221125_WJC_METTL3_EV_vs_WT_F08.21797.21797.4 9.64E-08 22/120 R.AAQLVDKDSTFLSTLEHHLSR.Y "sp|Q969V3|NCLN_HUMAN,tr|K7EMW4|K7EMW4_HUMAN,tr|K7ELZ9|K7ELZ9_HUMAN,tr|A0A0C4DGP7|A0A0C4DGP7_HUMAN" 4 2367.2183 1.36 122589 21797 4 2367.22624 592.8118 Nicalin OS=Homo sapiens OX=9606 GN=NCLN PE=1 SV=2 6 3545.6 - 413365 - - - 3.3656 - 3.952 0.554 - 457.3 1 2 1 0.008 21 0 0 0 3.94E+07 2.89E+07 - - - 4.5002 0.9995 221125_WJC_METTL3_EV_vs_WT_F08.21798.21798.3 0.000919 Nov-84 K.VQALEEANNDLENKIQDWYDKK.G sp|P35527|K1C9_HUMAN 1 2662.2875 6.23 122590 21798 3 2662.291922 888.4364 "Keratin, type I cytoskeletal 9 OS=Homo sapiens OX=9606 GN=KRT9 PE=1 SV=3" 4.3 3545.8 - 224658 - - - 1.6704 - 2.275 0.453 - 102.9 1 2 1 0.0044 22 0 0 0 6.08E+06 9.76E+05 - - - 5.538 0.992 221125_WJC_METTL3_EV_vs_WT_F08.21809.21809.3 0.000482 11/128 R.SDSPVPTAPTSGGPK[136.11]PSTASAVPELATDPELEK[136.11].K "sp|Q86U44|MTA70_HUMAN,tr|B4E349|B4E349_HUMAN,tr|F5H6D8|F5H6D8_HUMAN,tr|B4DTN4|B4DTN4_HUMAN" 4 3248.6271 0.34 122595 21809 3 3249.632484 1083.883 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 4.18 3547.1 - 229343 - - - 309.4803 - 1.957 0.398 - 47 1 2 0 1.0054 33 0 0 0 8.94E+06 2.65E+07 - - - 4.2435 1 221125_WJC_METTL3_EV_vs_WT_F08.21810.21810.3 3.68E-07 Dec-84 R.HDSEQDNSDNNTIFVQGLGENV.T sp|P35637|FUS_HUMAN 1 2431.0524 - 122596 21810 3 2431.057313 811.3581 RNA-binding protein FUS OS=Homo sapiens OX=9606 GN=FUS PE=1 SV=1 3.77 3547.2 - 296286 - - - 2.025 - 2.651 0.7 - 143.6 1 1 0 0.0049 22 0 0 0 - - - - - 8.6544 0.9885 221125_WJC_METTL3_EV_vs_WT_F08.21811.21811.4 0.122 7/102 K.SK[136.11]GLAPDLPEDLYHLIK[136.11]K[136.11].A "sp|P62277|RS13_HUMAN,tr|J3KMX5|J3KMX5_HUMAN" 2 2060.1732 0.98 122597 21811 4 2060.17708 516.0506 40S ribosomal protein S13 OS=Homo sapiens OX=9606 GN=RPS13 PE=1 SV=2 6.47 3547.3 - 133517 - - - 1.8702 - 1.937 0.266 - 39.3 1 2 1 0.0039 18 0 0 0 5.09E+06 5.21E+06 - - - 1.7667 0.9918 221125_WJC_METTL3_EV_vs_WT_F08.21816.21816.4 7.06E-05 13/102 K.SKGLAPDLPEDLYHLIKK.A "sp|P62277|RS13_HUMAN,tr|J3KMX5|J3KMX5_HUMAN" 2 2036.1306 0.98 122600 21816 4 2036.140052 510.0399 40S ribosomal protein S13 OS=Homo sapiens OX=9606 GN=RPS13 PE=1 SV=2 6.47 3548 - 142280 - - - 4.6289 - 2.007 0.384 - 70.4 1 2 1 0.0094 18 0 0 0 5.09E+06 5.21E+06 - - - 2.8044 0.9606 221125_WJC_METTL3_EV_vs_WT_F08.21821.21821.3 0.0762 Dec-60 R.DGLK[136.11]LMLLLEVISGER[166.11].L "sp|O43707|ACTN4_HUMAN,sp|P12814|ACTN1_HUMAN,tr|A0A804HK61|A0A804HK61_HUMAN,tr|A0A804HIN7|A0A804HIN7_HUMAN,tr|G3V5M4|G3V5M4_HUMAN,tr|A0A804HLF4|A0A804HLF4_HUMAN,tr|A0A804HIY0|A0A804HIY0_HUMAN,tr|A0A7I2V4Y4|A0A7I2V4Y4_HUMAN,tr|A0A804HII9|A0A804HII9_HUMAN,tr|A0A804HJQ9|A0A804HJQ9_HUMAN,tr|F5GXS2|F5GXS2_HUMAN,tr|A0A804HKE2|A0A804HKE2_HUMAN,tr|G3V2N5|G3V2N5_HUMAN,tr|A0A804HLD0|A0A804HLD0_HUMAN,tr|H7C144|H7C144_HUMAN" 15 1803.0295 0 122602 21821 3 1803.035687 602.0171 Alpha-actinin-4 OS=Homo sapiens OX=9606 GN=ACTN4 PE=1 SV=2 4.68 3548.6 - 779101 - - - 3.4442 - 2.081 0.227 - 185.9 1 2 1 0.0062 16 0 0 0 5.67E+05 1.25E+08 - - - 2.9495 1 221125_WJC_METTL3_EV_vs_WT_F08.21825.21825.4 1.96E-08 15/234 K.TAQALAQLAAQHSQSGSTTTSSWDMGSTTQSPSLVQYDLK[136.11].N "sp|Q14157|UBP2L_HUMAN,tr|F8W726|F8W726_HUMAN" 2 4189.9953 1.94 122604 21825 4 4189.996015 1048.5061 Ubiquitin-associated protein 2-like OS=Homo sapiens OX=9606 GN=UBAP2L PE=1 SV=2 5.18 3549.1 - 266639 - - - 0.1597 - 2.639 0.608 - 93.2 1 2 0 0.0007 40 0 0 0 5.52E+07 2.85E+07 - - - 4.798 0.966 221125_WJC_METTL3_EV_vs_WT_F08.21826.21826.4 0.0108 12/120 R.K[136.11]NTDK[136.11]NYLNFVSPLPDIVGQK[136.11].S sp|Q9Y2X9|ZN281_HUMAN 1 2413.3068 1.53 122605 21826 4 2413.31957 604.334 Zinc finger protein 281 OS=Homo sapiens OX=9606 GN=ZNF281 PE=1 SV=1 8.43 3549.2 - 310817 - - - 5.3077 - 2.282 0.326 - 84.2 1 2 1 0.0128 21 0 0 0 2.15E+07 1.41E+07 - - - 2.3328 1 221125_WJC_METTL3_EV_vs_WT_F08.21837.21837.4 5.04E-13 28/252 K.VVGSAVGSGSITSNIVASNSLPPATIAPPK[136.11]PASWADIASK[136.11]PAK[136.11].Q sp|Q9Y5A9|YTHD2_HUMAN 1 4137.2536 1.57 122610 21837 4 4137.264063 1035.3207 YTH domain-containing family protein 2 OS=Homo sapiens OX=9606 GN=YTHDF2 PE=1 SV=2 9.7 3550.7 - 690978 - - - 2.5266 - 3.846 0.652 - 171.7 1 2 0 0.0105 43 0 0 0 1.91E+08 1.22E+08 - - - 5.2815 0.9794 221125_WJC_METTL3_EV_vs_WT_F08.21839.21839.2 0.205 30-Aug R.DGLK[136.11]LMLLLEVISGER[166.11].L "sp|O43707|ACTN4_HUMAN,sp|P12814|ACTN1_HUMAN,tr|A0A804HK61|A0A804HK61_HUMAN,tr|A0A804HIN7|A0A804HIN7_HUMAN,tr|G3V5M4|G3V5M4_HUMAN,tr|A0A804HLF4|A0A804HLF4_HUMAN,tr|A0A804HIY0|A0A804HIY0_HUMAN,tr|A0A7I2V4Y4|A0A7I2V4Y4_HUMAN,tr|A0A804HII9|A0A804HII9_HUMAN,tr|A0A804HJQ9|A0A804HJQ9_HUMAN,tr|F5GXS2|F5GXS2_HUMAN,tr|A0A804HKE2|A0A804HKE2_HUMAN,tr|G3V2N5|G3V2N5_HUMAN,tr|A0A804HLD0|A0A804HLD0_HUMAN,tr|H7C144|H7C144_HUMAN" 15 1803.0295 0.001 122612 21839 2 1803.028794 902.522 Alpha-actinin-4 OS=Homo sapiens OX=9606 GN=ACTN4 PE=1 SV=2 4.68 3550.9 - 132726 - - - -0.3788 - 1.713 0.201 - 180.6 1 2 1 -0.0007 16 0 0 0 0.00E+00 6.26E+06 - - - 1.8487 1 221125_WJC_METTL3_EV_vs_WT_F08.21851.21851.4 6.34E-10 25/144 K.GDTNIKPILQVINIRPITTGNSPPR.Y "sp|P27694|RFA1_HUMAN,tr|I3L2M5|I3L2M5_HUMAN,tr|I3L524|I3L524_HUMAN" 3 2713.5239 1.33 122619 21851 4 2713.531303 679.3883 Replication protein A 70 kDa DNA-binding subunit OS=Homo sapiens OX=9606 GN=RPA1 PE=1 SV=2 10.84 3552.5 - 589563 - - - 2.7289 - 3.988 0.616 - 359.5 1 2 0 0.0074 25 0 0 0 1.85E+08 1.39E+08 - - - 5.0257 0.9827 221125_WJC_METTL3_EV_vs_WT_F08.21858.21858.3 0.0517 Aug-80 R.K[136.11]NTDK[136.11]NYLNFVSPLPDIVGQK[136.11].S sp|Q9Y2X9|ZN281_HUMAN 1 2413.3068 1.42 122623 21858 3 2413.308303 805.4429 Zinc finger protein 281 OS=Homo sapiens OX=9606 GN=ZNF281 PE=1 SV=1 8.43 3553.4 - 304510 - - - 0.639 - 1.699 0.233 - 41.1 1 2 1 0.0015 21 0 0 0 3.99E+06 2.81E+06 - - - 2.408 1 221125_WJC_METTL3_EV_vs_WT_F08.21859.21859.4 4.76E-14 19/192 R.K[136.11]EAESC[160.03]DC[160.03]LQGFQLTHSLGGGTGSGMGTLLISK[136.11].L "sp|P04350|TBB4A_HUMAN,sp|A6NNZ2|TBB8B_HUMAN,sp|P07437|TBB5_HUMAN,sp|P68371|TBB4B_HUMAN,sp|Q3ZCM7|TBB8_HUMAN,tr|Q5ST81|Q5ST81_HUMAN,tr|Q5JP53|Q5JP53_HUMAN,tr|M0R042|M0R042_HUMAN,tr|A0A075B736|A0A075B736_HUMAN,tr|Q5SQY0|Q5SQY0_HUMAN" 10 3454.6502 0.58 122624 21859 4 3454.648836 864.6698 Tubulin beta-4A chain OS=Homo sapiens OX=9606 GN=TUBB4A PE=1 SV=2 5.44 3553.6 - 528560 - - - -0.3879 - 3.782 0.751 - 135.9 1 2 0 -0.0013 33 0 0 0 2.50E+07 4.29E+07 - - - 6.1615 1 221125_WJC_METTL3_EV_vs_WT_F08.21864.21864.4 7.45E-11 27/144 K.GDTNIK[136.11]PILQVINIR[166.11]PITTGNSPPR[166.11].Y "sp|P27694|RFA1_HUMAN,tr|I3L2M5|I3L2M5_HUMAN,tr|I3L524|I3L524_HUMAN" 3 2741.5546 1.33 122627 21864 4 2741.560644 686.3959 Replication protein A 70 kDa DNA-binding subunit OS=Homo sapiens OX=9606 GN=RPA1 PE=1 SV=2 10.84 3554.2 - 1.08E+06 - - - 2.1907 - 4.299 0.665 - 451.2 1 2 0 0.006 25 0 0 0 1.85E+08 1.39E+08 - - - 5.4764 0.9977 221125_WJC_METTL3_EV_vs_WT_F08.21866.21866.4 0.000104 14/120 R.KNTDKNYLNFVSPLPDIVGQK.S sp|Q9Y2X9|ZN281_HUMAN 1 2389.2642 1.54 122629 21866 4 2389.27064 598.3233 Zinc finger protein 281 OS=Homo sapiens OX=9606 GN=ZNF281 PE=1 SV=1 8.43 3554.5 - 1.38E+06 - - - 2.7117 - 2.618 0.367 - 89.4 1 2 1 0.0065 21 0 0 0 2.17E+07 1.41E+07 - - - 2.7368 0.9842 221125_WJC_METTL3_EV_vs_WT_F08.21869.21869.2 0.111 14-Jun R.LTILELER[166.11].E sp|Q569K6|CC157_HUMAN 1 995.5891 0 122632 21869 2 995.590233 498.8018 Coiled-coil domain-containing protein 157 OS=Homo sapiens OX=9606 GN=CCDC157 PE=1 SV=3 4.53 3554.9 - 230641 - - - 1.1712 - 1.476 0.046 - 102.6 1 2 0 0.0012 8 0 0 0 6.64E+04 5.30E+07 - - - 0.5546 1 221125_WJC_METTL3_EV_vs_WT_F08.21872.21872.4 4.73E-19 27/192 R.KEAESC[160.03]DC[160.03]LQGFQLTHSLGGGTGSGMGTLLISK.L "sp|P04350|TBB4A_HUMAN,sp|A6NNZ2|TBB8B_HUMAN,sp|P07437|TBB5_HUMAN,sp|P68371|TBB4B_HUMAN,sp|Q3ZCM7|TBB8_HUMAN,tr|Q5ST81|Q5ST81_HUMAN,tr|Q5JP53|Q5JP53_HUMAN,tr|M0R042|M0R042_HUMAN,tr|A0A075B736|A0A075B736_HUMAN,tr|Q5SQY0|Q5SQY0_HUMAN" 10 3438.6218 0.58 122633 21872 4 3438.628978 860.6627 Tubulin beta-4A chain OS=Homo sapiens OX=9606 GN=TUBB4A PE=1 SV=2 5.44 3555.3 - 993108 - - - 2.0944 - 5.051 0.741 - 281.9 1 2 0 0.0072 33 0 0 0 2.50E+07 4.29E+07 - - - 6.1596 0.9922 221125_WJC_METTL3_EV_vs_WT_F08.21875.21875.4 0.000121 7/114 R.RKDGVFLYFEDNAGVIVNNK.G "sp|P62829|RL23_HUMAN,tr|J3KT29|J3KT29_HUMAN,tr|J3KTJ3|J3KTJ3_HUMAN" 3 2297.1804 0.93 122636 21875 4 2297.193026 575.3024 60S ribosomal protein L23 OS=Homo sapiens OX=9606 GN=RPL23 PE=1 SV=1 6.12 3555.6 - 229539 - - - 5.4828 - 2.091 0.425 - 34.4 1 2 1 0.0126 20 0 0 0 1.38E+07 1.48E+07 - - - 3.1683 0.996 221125_WJC_METTL3_EV_vs_WT_F08.21880.21880.4 0.00482 12/114 R.EFTMAEIEHFVDPSEKDHPK.F "sp|P41250|GARS_HUMAN,tr|H7C443|H7C443_HUMAN,tr|A0A6Q8PGI6|A0A6Q8PGI6_HUMAN,tr|A0A6Q8PGA8|A0A6Q8PGA8_HUMAN,tr|A0A6Q8PGW4|A0A6Q8PGW4_HUMAN,tr|A0A6Q8PGZ8|A0A6Q8PGZ8_HUMAN,tr|A0A6Q8PHH9|A0A6Q8PHH9_HUMAN,tr|A0A6Q8PHI7|A0A6Q8PHI7_HUMAN,tr|A0A6Q8PFZ6|A0A6Q8PFZ6_HUMAN" 9 2385.0947 1.21 122639 21880 4 2385.101775 597.281 Glycine--tRNA ligase OS=Homo sapiens OX=9606 GN=GARS1 PE=1 SV=3 4.63 3556.3 - 705896 - - - 2.9613 - 2.355 0.349 - 48.8 1 2 1 0.0071 20 0 0 0 2.45E+07 2.03E+07 - - - 2.5481 1 221125_WJC_METTL3_EV_vs_WT_F08.21882.21882.4 1.72E-14 19/186 R.FSFLSKPVDENHQQDGDEDSLVSHFYTNPIAK.P "sp|P52948|NUP98_HUMAN,tr|A0A3B3ITD8|A0A3B3ITD8_HUMAN" 2 3663.7118 1.96 122641 21882 4 3663.722014 916.9352 Nuclear pore complex protein Nup98-Nup96 OS=Homo sapiens OX=9606 GN=NUP98 PE=1 SV=4 4.51 3556.6 - 632980 - - - 2.7958 - 4.481 0.685 - 130.9 1 1 0 0.0102 32 0 0 0 5.03E+07 2.56E+07 - - - 5.6383 1 221125_WJC_METTL3_EV_vs_WT_F08.21883.21883.3 5.85E-11 13/92 R.NGPGFHNDIDSNSTIQEILIPASK.V sp|Q96I24|FUBP3_HUMAN 1 2566.2663 2.13 122642 21883 3 2566.274711 856.4294 Far upstream element-binding protein 3 OS=Homo sapiens OX=9606 GN=FUBP3 PE=1 SV=2 4.54 3556.7 - 346830 - - - 3.2596 - 2.903 0.682 - 84.4 1 2 0 0.0084 24 0 0 0 3.51E+07 1.65E+07 - - - 8.6166 1 221125_WJC_METTL3_EV_vs_WT_F08.21889.21889.4 3.65E-12 20/186 R.FSFLSK[136.11]PVDENHQQDGDEDSLVSHFYTNPIAK[136.11].P "sp|P52948|NUP98_HUMAN,tr|A0A3B3ITD8|A0A3B3ITD8_HUMAN" 2 3679.7402 1.97 122646 21889 4 3679.745499 920.9423 Nuclear pore complex protein Nup98-Nup96 OS=Homo sapiens OX=9606 GN=NUP98 PE=1 SV=4 4.51 3557.5 - 514732 - - - 1.4479 - 4.497 0.63 - 152 1 1 0 0.0053 32 0 0 0 5.02E+07 2.55E+07 - - - 5.162 0.9999 221125_WJC_METTL3_EV_vs_WT_F08.21892.21892.3 1.79E-06 Sep-60 R.IINEPTAAAIAYGLDR[166.11].T "sp|P0DMV8|HS71A_HUMAN,sp|P0DMV9|HS71B_HUMAN,sp|P17066|HSP76_HUMAN,tr|A0A0G2JIW1|A0A0G2JIW1_HUMAN" 4 1696.9024 0.15 122649 21892 3 1696.904592 566.6414 Heat shock 70 kDa protein 1A OS=Homo sapiens OX=9606 GN=HSPA1A PE=1 SV=1 4.37 3557.9 - 117398 - - - 1.3183 - 1.994 0.48 - 98 1 2 0 0.0022 16 0 0 0 1.35E+06 9.07E+06 - - - 5.6617 0.9999 221125_WJC_METTL3_EV_vs_WT_F08.21905.21905.3 2.20E-06 13/96 K.GDTNIKPILQVINIRPITTGNSPPR.Y "sp|P27694|RFA1_HUMAN,tr|I3L2M5|I3L2M5_HUMAN,tr|I3L524|I3L524_HUMAN" 3 2713.5239 1.4 122656 21905 3 2713.531458 905.5152 Replication protein A 70 kDa DNA-binding subunit OS=Homo sapiens OX=9606 GN=RPA1 PE=1 SV=2 10.84 3559.7 - 456172 - - - 2.786 - 1.766 0.606 - 75 1 2 0 0.0076 25 0 0 0 1.79E+07 1.27E+07 - - - 6.6026 0.9983 221125_WJC_METTL3_EV_vs_WT_F08.21907.21907.3 3.65E-07 26/80 R.K[136.11]HAASDVDLEIESLLNQQSTK[136.11].E "sp|Q86U44|MTA70_HUMAN,tr|F5H6D8|F5H6D8_HUMAN,tr|H0YFV6|H0YFV6_HUMAN,tr|B4DTN4|B4DTN4_HUMAN" 4 2341.2096 0.04 122657 21907 3 2342.206594 781.4105 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 4.75 3559.9 - 3.37E+06 - - - 425.8376 - 4.223 0.487 - 1033.3 1 2 0 0.997 21 0 0 0 3.17E+07 7.31E+08 - - - 7.1471 1 221125_WJC_METTL3_EV_vs_WT_F08.21908.21908.2 7.48E-08 13/30 R.IINEPTAAAIAYGLDR[166.11].T "sp|P0DMV8|HS71A_HUMAN,sp|P0DMV9|HS71B_HUMAN,sp|P17066|HSP76_HUMAN,tr|A0A0G2JIW1|A0A0G2JIW1_HUMAN" 4 1696.9024 0.05 122658 21908 2 1696.903835 849.4585 Heat shock 70 kDa protein 1A OS=Homo sapiens OX=9606 GN=HSPA1A PE=1 SV=1 4.37 3560.1 - 345526 - - - 0.8722 - 3.045 0.588 - 442.1 1 2 0 0.0015 16 0 0 0 4.71E+05 9.85E+06 - - - 6.1211 0.9998 221125_WJC_METTL3_EV_vs_WT_F08.21911.21911.4 1.07E-07 16/150 K.EVLAGRPLFPHVLC[160.03]HNC[160.03]AVEFNFGQK.E "sp|Q00839|HNRPU_HUMAN,tr|A0A1W2PQL0|A0A1W2PQL0_HUMAN,tr|A0A1W2PPL4|A0A1W2PPL4_HUMAN,tr|A0A1W2PQ74|A0A1W2PQ74_HUMAN,tr|Q5RI18|Q5RI18_HUMAN,tr|A0A1W2PP35|A0A1W2PP35_HUMAN,tr|A0A1W2PPS1|A0A1W2PPS1_HUMAN,tr|A0A1W2PRZ7|A0A1W2PRZ7_HUMAN,tr|A0A1W2PPH7|A0A1W2PPH7_HUMAN,tr|A0A1W2PP34|A0A1W2PP34_HUMAN,tr|A0A1X7SBS1|A0A1X7SBS1_HUMAN" 11 3038.5007 2.1 122660 21911 4 3038.51096 760.6325 Heterogeneous nuclear ribonucleoprotein U OS=Homo sapiens OX=9606 GN=HNRNPU PE=1 SV=6 6.99 3560.4 - 475076 - - - 3.3645 - 2.746 0.497 - 86.1 1 2 0 0.0102 26 0 0 0 3.03E+07 1.45E+07 - - - 3.8677 1 221125_WJC_METTL3_EV_vs_WT_F08.21913.21913.4 1.56E-09 28/252 K.VVGSAVGSGSITSNIVASNSLPPATIAPPKPASWADIASKPAK.Q sp|Q9Y5A9|YTHD2_HUMAN 1 4113.211 1.6 122661 21913 4 4113.221313 1029.31 YTH domain-containing family protein 2 OS=Homo sapiens OX=9606 GN=YTHDF2 PE=1 SV=2 9.7 3560.6 - 622040 - - - 2.5049 - 4.173 0.599 - 164.2 1 2 0 0.0103 43 0 0 0 3.15E+07 1.97E+07 - - - 4.8434 0.9984 221125_WJC_METTL3_EV_vs_WT_F08.21915.21915.4 9.79E-11 27/120 R.K[136.11]HAASDVDLEIESLLNQQSTK[136.11].E "sp|Q86U44|MTA70_HUMAN,tr|F5H6D8|F5H6D8_HUMAN,tr|H0YFV6|H0YFV6_HUMAN,tr|B4DTN4|B4DTN4_HUMAN" 4 2341.2096 0.14 122663 21915 4 2342.206487 586.3097 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 4.75 3560.8 - 6.72E+06 - - - 425.7919 - 4.557 0.576 - 815.6 1 2 0 0.9969 21 0 0 0 6.39E+07 4.59E+08 - - - 4.4648 0.9894 221125_WJC_METTL3_EV_vs_WT_F08.21929.21929.4 5.11E-07 15/216 R.GSDIKDLTVC[160.03]EPPKPQC[160.03]SLPQDPAIVQSSLGSSTSSF.Q "sp|Q8ND56|LS14A_HUMAN,tr|A0A140TA76|A0A140TA76_HUMAN,tr|K7EMZ9|K7EMZ9_HUMAN" 3 3931.8819 1.04 122672 21929 4 3931.883396 983.9778 Protein LSM14 homolog A OS=Homo sapiens OX=9606 GN=LSM14A PE=1 SV=3 4.23 3562.6 - 427484 - - - 0.3678 - 2.448 0.554 - 54.8 1 1 1 0.0014 37 0 0 0 2.29E+07 2.21E+07 - - - 4.3101 1 221125_WJC_METTL3_EV_vs_WT_F08.21930.21930.3 6.33E-10 18/92 R.NGPGFHNDIDSNSTIQEILIPASK[136.11].V sp|Q96I24|FUBP3_HUMAN 1 2574.2805 2.13 122673 21930 3 2574.29133 859.1008 Far upstream element-binding protein 3 OS=Homo sapiens OX=9606 GN=FUBP3 PE=1 SV=2 4.54 3562.8 - 340446 - - - 4.1891 - 3.464 0.716 - 183.5 1 2 0 0.0108 24 0 0 0 3.51E+07 1.64E+07 - - - 9.4054 0.9873 221125_WJC_METTL3_EV_vs_WT_F08.21934.21934.2 3.61E-06 30-Aug R.R[166.11]AEQDSTTVAAFASSL.V "sp|Q86U44|MTA70_HUMAN,tr|F5H6D8|F5H6D8_HUMAN,tr|H0YFV6|H0YFV6_HUMAN,tr|B4DTN4|B4DTN4_HUMAN" 4 1662.8088 0.02 122675 21934 2 1662.807478 832.4117 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 4.37 3563.3 - 174666 - - - -0.8245 - 1.926 0.472 - 106.3 1 1 0 -0.0014 16 0 0 0 1.72E+05 8.91E+06 - - - 4.1382 0.9888 221125_WJC_METTL3_EV_vs_WT_F08.21942.21942.3 1.50E-06 11/144 R.GSDIKDLTVC[160.03]EPPKPQC[160.03]SLPQDPAIVQSSLGSSTSSF.Q "sp|Q8ND56|LS14A_HUMAN,tr|A0A140TA76|A0A140TA76_HUMAN,tr|K7EMZ9|K7EMZ9_HUMAN" 3 3931.8819 1.13 122680 21942 3 3931.883288 1311.6346 Protein LSM14 homolog A OS=Homo sapiens OX=9606 GN=LSM14A PE=1 SV=3 4.23 3564.4 - 240602 - - - 0.3403 - 2.432 0.561 - 47.7 1 1 1 0.0013 37 0 0 0 6.99E+06 6.18E+06 - - - 6.8388 0.9997 221125_WJC_METTL3_EV_vs_WT_F08.21944.21944.4 0.000201 8/222 K.EAASLLEAGEERPGEQSQGTQSQGSALQDPEC[160.03]FAHLLR.F "sp|O00255|MEN1_HUMAN,tr|A0A5F9ZHS3|A0A5F9ZHS3_HUMAN" 2 4095.9192 1.61 122682 21944 4 4095.928059 1024.9871 Menin OS=Homo sapiens OX=9606 GN=MEN1 PE=1 SV=4 4.3 3564.6 - 188204 - - - 2.1592 - 2.136 0.406 - 14.7 1 2 0 0.0088 38 0 0 0 2.15E+06 1.33E+06 - - - 2.9787 0.9937 221125_WJC_METTL3_EV_vs_WT_F08.21957.21957.4 8.39E-10 22/216 R.GSDIK[136.11]DLTVC[160.03]EPPK[136.11]PQC[160.03]SLPQDPAIVQSSLGSSTSSF.Q "sp|Q8ND56|LS14A_HUMAN,tr|A0A140TA76|A0A140TA76_HUMAN,tr|K7EMZ9|K7EMZ9_HUMAN" 3 3947.9104 1.04 122689 21957 4 3947.913918 987.9849 Protein LSM14 homolog A OS=Homo sapiens OX=9606 GN=LSM14A PE=1 SV=3 4.23 3566.3 - 646553 - - - 0.9038 - 3.507 0.617 - 143.7 1 1 1 0.0036 37 0 0 0 2.32E+07 2.24E+07 - - - 4.9632 1 221125_WJC_METTL3_EV_vs_WT_F08.21959.21959.3 9.77E-10 22/60 R.HGVQELEIELQSQLSK.K "sp|P35527|K1C9_HUMAN,tr|K7EQQ3|K7EQQ3_HUMAN" 2 1836.9581 666.12 122691 21959 3 1836.962436 613.3267 "Keratin, type I cytoskeletal 9 OS=Homo sapiens OX=9606 GN=KRT9 PE=1 SV=3" 4.75 3566.5 - 856857 - - - 2.3376 - 3.433 0.519 - 371.1 1 2 0 0.0043 16 0 0 0 3.35E+07 5.03E+04 - - - 7.49 0.9998 221125_WJC_METTL3_EV_vs_WT_F08.21963.21963.3 0.00426 8/120 R.NC[160.03]SVTGIDDLEQIPADTTDINHLETQPVSSK[136.11].D "sp|Q8NG31|KNL1_HUMAN,tr|E9PPJ1|E9PPJ1_HUMAN,tr|H0YCZ2|H0YCZ2_HUMAN" 3 3404.6133 0.1 122693 21963 3 3404.618554 1135.8784 Kinetochore scaffold 1 OS=Homo sapiens OX=9606 GN=KNL1 PE=1 SV=3 3.96 3567.1 - 145358 - - - 1.5406 - 1.401 0.496 - 35.9 1 2 0 0.0052 31 0 0 0 3.62E+05 3.48E+06 - - - 4.8442 1 221125_WJC_METTL3_EV_vs_WT_F08.21977.21977.3 4.15E-12 19/116 K.TPSTMENDSSNLDPSQAPSLAQPLVFSNSK.Q "sp|Q14157|UBP2L_HUMAN,tr|F8W726|F8W726_HUMAN,tr|Q5VU77|Q5VU77_HUMAN" 3 3161.4823 2.65 122701 21977 3 3161.480925 1054.8347 Ubiquitin-associated protein 2-like OS=Homo sapiens OX=9606 GN=UBAP2L PE=1 SV=2 4.03 3569 - 463641 - - - -0.4311 - 3.169 0.713 - 233.6 1 2 0 -0.0014 30 0 0 0 2.20E+07 8.30E+06 - - - 9.1425 0.9992 221125_WJC_METTL3_EV_vs_WT_F08.21981.21981.4 1.59E-07 13/114 R.TREGNDLYHEMIESGVINLK.D "sp|P06576|ATPB_HUMAN,tr|F8W079|F8W079_HUMAN,tr|H0YI37|H0YI37_HUMAN,tr|F8W0P7|F8W0P7_HUMAN,tr|H0YH81|H0YH81_HUMAN" 5 2317.1372 7.86 122703 21981 4 2317.147608 580.2916 "ATP synthase subunit beta, mitochondrial OS=Homo sapiens OX=9606 GN=ATP5F1B PE=1 SV=3" 4.83 3569.6 - 209405 - - - 4.4719 - 2.399 0.548 - 97.3 1 2 1 0.0104 20 0 0 0 6.08E+06 7.74E+05 - - - 4.2855 1 221125_WJC_METTL3_EV_vs_WT_F08.21982.21982.2 9.85E-10 13/30 K.SYELPDGQVITIGNER.F "sp|Q6S8J3|POTEE_HUMAN,sp|P63261|ACTG_HUMAN,sp|P68133|ACTS_HUMAN,sp|P62736|ACTA_HUMAN,sp|Q9BYX7|ACTBM_HUMAN,sp|P68032|ACTC_HUMAN,sp|Q562R1|ACTBL_HUMAN,sp|P60709|ACTB_HUMAN,sp|P63267|ACTH_HUMAN,sp|A5A3E0|POTEF_HUMAN,tr|A0A804GS07|A0A804GS07_HUMAN,tr|E7EVS6|E7EVS6_HUMAN,tr|A0A6Q8PFE4|A0A6Q8PFE4_HUMAN,tr|A0A2R8YEA7|A0A2R8YEA7_HUMAN,tr|A0A804HKV3|A0A804HKV3_HUMAN,tr|A0A2R8Y793|A0A2R8Y793_HUMAN,tr|I3L4N8|I3L4N8_HUMAN,tr|A6NL76|A6NL76_HUMAN" 18 1789.8846 8.5 122704 21982 2 1789.888347 895.9496 POTE ankyrin domain family member E OS=Homo sapiens OX=9606 GN=POTEE PE=2 SV=3 4.14 3569.7 - 239258 - - - 2.0694 - 2.711 0.683 - 487.6 1 2 0 0.0037 16 0 0 0 8.25E+06 9.71E+05 - - - 6.5364 1 221125_WJC_METTL3_EV_vs_WT_F08.21986.21986.3 1.80E-12 15/116 K.TPSTMENDSSNLDPSQAPSLAQPLVFSNSK[136.11].Q "sp|Q14157|UBP2L_HUMAN,tr|F8W726|F8W726_HUMAN,tr|Q5VU77|Q5VU77_HUMAN" 3 3169.4965 2.65 122706 21986 3 3169.498951 1057.5061 Ubiquitin-associated protein 2-like OS=Homo sapiens OX=9606 GN=UBAP2L PE=1 SV=2 4.03 3570.2 - 234216 - - - 0.7771 - 2.951 0.76 - 159.9 1 2 0 0.0025 30 0 0 0 2.20E+07 8.30E+06 - - - 9.5022 1 221125_WJC_METTL3_EV_vs_WT_F08.21998.21998.3 9.71E-16 17/112 R.QHFSPLSLLTPC[160.03]SSASNDSSAQSVSSGVR.A "sp|O75179|ANR17_HUMAN,tr|H0YM23|H0YM23_HUMAN" 2 3005.4149 9.43 122713 21998 3 3005.422312 1002.8122 Ankyrin repeat domain-containing protein 17 OS=Homo sapiens OX=9606 GN=ANKRD17 PE=1 SV=3 6.74 3571.8 - 173936 - - - 2.4735 - 4.014 0.767 - 286.6 1 2 0 0.0074 29 0 0 0 5.58E+06 5.92E+05 - - - 10.2866 0.9971 221125_WJC_METTL3_EV_vs_WT_F08.22006.22006.4 0.00161 15/156 K.C[160.03]SENK[136.11]LPAELQELPGLSHQYWSAPSDK[136.11].E "sp|P27695|APEX1_HUMAN,tr|G3V3C7|G3V3C7_HUMAN,tr|G3V5M0|G3V5M0_HUMAN,tr|G3V3M6|G3V3M6_HUMAN,tr|H7C4A8|H7C4A8_HUMAN,tr|A0A0C4DGK8|A0A0C4DGK8_HUMAN,tr|G3V359|G3V359_HUMAN,tr|G3V5Q1|G3V5Q1_HUMAN" 8 3099.4943 0.14 122717 22006 4 3099.509838 775.8808 DNA-(apurinic or apyrimidinic site) endonuclease OS=Homo sapiens OX=9606 GN=APEX1 PE=1 SV=2 4.83 3572.9 - 209777 - - - 5.0289 - 2.665 0.467 - 99.1 1 2 1 0.0156 27 0 0 0 5.91E+05 4.22E+06 - - - 3.5931 0.9999 221125_WJC_METTL3_EV_vs_WT_F08.22008.22008.3 2.78E-05 Sep-52 K.K[136.11]GPGEVAGTVTGQK[136.11].R "sp|Q86U44|MTA70_HUMAN,tr|F5H6D8|F5H6D8_HUMAN,tr|H0YFV6|H0YFV6_HUMAN,tr|B4DTN4|B4DTN4_HUMAN" 4 1343.738 0 122718 22008 3 1343.741572 448.9199 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 8.59 3573.3 - 87598.8 - - - 2.6739 - 2.002 0.511 - 145.1 1 2 0 0.0036 14 0 0 0 1.73E+04 6.33E+06 - - - 6.0809 0.9999 221125_WJC_METTL3_EV_vs_WT_F08.22012.22012.4 6.40E-07 14/204 R.SQPAFMQSSLSQPSVVLSGTAIHNFPTVQHQELAK.A "sp|Q9Y520|PRC2C_HUMAN,tr|E7EPN9|E7EPN9_HUMAN,tr|H7C5N8|H7C5N8_HUMAN,tr|A0A2R8Y7F4|A0A2R8Y7F4_HUMAN,tr|A0A2R8YET2|A0A2R8YET2_HUMAN" 5 3763.8992 2.77 122720 22012 4 3763.915564 941.9821 Protein PRRC2C OS=Homo sapiens OX=9606 GN=PRRC2C PE=1 SV=4 6.66 3573.8 - 231860 - - - 4.3489 - 3.125 0.601 - 73.8 1 2 0 0.0164 35 0 0 0 9.16E+06 3.31E+06 - - - 4.7904 1 221125_WJC_METTL3_EV_vs_WT_F08.22013.22013.3 7.73E-11 13/108 K.NSHSSSYTPNSFSSEELQAEPLDLSLPK.Q "sp|O60315|ZEB2_HUMAN,tr|U3KQ51|U3KQ51_HUMAN,tr|A0JP08|A0JP08_HUMAN,tr|A0A1B0GW50|A0A1B0GW50_HUMAN,tr|A0A1B0GV02|A0A1B0GV02_HUMAN,tr|A0A1B0GVV8|A0A1B0GVV8_HUMAN" 6 3063.4309 5.4 122721 22013 3 3063.43912 1022.1509 Zinc finger E-box-binding homeobox 2 OS=Homo sapiens OX=9606 GN=ZEB2 PE=1 SV=1 4.4 3573.9 - 197822 - - - 2.6816 - 2.834 0.707 - 131.6 1 2 0 0.0082 28 0 0 0 5.59E+06 1.04E+06 - - - 8.8166 1 221125_WJC_METTL3_EV_vs_WT_F08.22014.22014.4 2.75E-14 21/138 K.DYALHWLVLGTHTSDEQNHLVVAR.V "sp|Q16576|RBBP7_HUMAN,tr|C9J7L0|C9J7L0_HUMAN,tr|E9PC52|E9PC52_HUMAN" 3 2773.3936 1.28 122722 22014 4 2773.407321 694.3557 Histone-binding protein RBBP7 OS=Homo sapiens OX=9606 GN=RBBP7 PE=1 SV=1 5.73 3574 - 235248 - - - 4.943 - 3.888 0.703 - 273.1 1 2 0 0.0137 24 0 0 0 3.53E+06 2.76E+06 - - - 5.777 0.9994 221125_WJC_METTL3_EV_vs_WT_F08.22016.22016.2 7.22E-06 18-Oct R.FEELNADLFR[166.11].G "sp|P54652|HSP72_HUMAN,sp|P11142|HSP7C_HUMAN,tr|E9PNE6|E9PNE6_HUMAN,tr|A8K7Q2|A8K7Q2_HUMAN,tr|E9PKE3|E9PKE3_HUMAN,tr|E9PN89|E9PN89_HUMAN" 6 1262.6171 0.46 122724 22016 2 1262.62133 632.3158 Heat shock-related 70 kDa protein 2 OS=Homo sapiens OX=9606 GN=HSPA2 PE=1 SV=1 4.14 3574.3 - 119612 - - - 3.3724 - 2.207 0.554 - 333.1 1 2 0 0.0043 10 0 0 0 1.85E+06 4.08E+06 - - - 5.3412 0.9966 221125_WJC_METTL3_EV_vs_WT_F08.22032.22032.3 9.61E-07 Jul-92 L.QTSSTGNEAGGVNSNQFEELLQER.D "sp|Q15643|TRIPB_HUMAN,tr|H0YJ97|H0YJ97_HUMAN" 2 2594.1845 1.3 122732 22032 3 2594.189263 865.7354 Thyroid receptor-interacting protein 11 OS=Homo sapiens OX=9606 GN=TRIP11 PE=1 SV=3 4.09 3576.5 - 150339 - - - 1.8488 - 2.12 0.617 - 48.5 1 1 0 0.0048 24 0 0 0 5.65E+06 4.34E+06 - - - 7.1628 0.9997 221125_WJC_METTL3_EV_vs_WT_F08.22034.22034.4 4.42E-08 11/138 K.DYALHWLVLGTHTSDEQNHLVVAR[166.11].V "sp|Q16576|RBBP7_HUMAN,tr|C9J7L0|C9J7L0_HUMAN,tr|E9PC52|E9PC52_HUMAN" 3 2783.4019 1.23 122733 22034 4 2783.41469 696.8577 Histone-binding protein RBBP7 OS=Homo sapiens OX=9606 GN=RBBP7 PE=1 SV=1 5.73 3576.7 - 173259 - - - 4.6016 - 2.462 0.525 - 47.8 1 2 0 0.0128 24 0 0 0 3.32E+06 2.70E+06 - - - 4.0812 0.9992 221125_WJC_METTL3_EV_vs_WT_F08.22035.22035.4 0.000569 11/174 K.SPQPPVEEEDEHFDDTVVC[160.03]LDTYNC[160.03]DLHFK[136.11].L "sp|Q00839|HNRPU_HUMAN,tr|Q5RI18|Q5RI18_HUMAN,tr|A0A1W2PP35|A0A1W2PP35_HUMAN,tr|A0A1W2PPS1|A0A1W2PPS1_HUMAN,tr|A0A1W2PRI6|A0A1W2PRI6_HUMAN" 5 3642.5646 1.06 122734 22035 4 3643.565955 911.6484 Heterogeneous nuclear ribonucleoprotein U OS=Homo sapiens OX=9606 GN=HNRNPU PE=1 SV=6 3.97 3576.9 - 130925 - - - 274.8915 - 2.475 0.543 - 58.3 1 2 0 1.0013 30 0 0 0 1.39E+06 1.32E+06 - - - 3.9522 0.9999 221125_WJC_METTL3_EV_vs_WT_F08.22036.22036.4 0.00122 15/204 R.SQPAFMQSSLSQPSVVLSGTAIHNFPTVQHQELAK[136.11].A "sp|Q9Y520|PRC2C_HUMAN,tr|E7EPN9|E7EPN9_HUMAN,tr|H7C5N8|H7C5N8_HUMAN,tr|A0A2R8Y7F4|A0A2R8Y7F4_HUMAN,tr|A0A2R8YET2|A0A2R8YET2_HUMAN" 5 3771.9134 2.77 122735 22036 4 3771.922935 943.9856 Protein PRRC2C OS=Homo sapiens OX=9606 GN=PRRC2C PE=1 SV=4 6.66 3577 - 337024 - - - 2.5292 - 2.909 0.478 - 82.8 1 2 0 0.0095 35 0 0 0 9.16E+06 3.31E+06 - - - 3.7004 0.9984 221125_WJC_METTL3_EV_vs_WT_F08.22043.22043.3 1.88E-06 Nov-92 L.QTSSTGNEAGGVNSNQFEELLQER[166.11].D "sp|Q15643|TRIPB_HUMAN,tr|H0YJ97|H0YJ97_HUMAN" 2 2604.1927 1.3 122738 22043 3 2604.191695 869.0715 Thyroid receptor-interacting protein 11 OS=Homo sapiens OX=9606 GN=TRIP11 PE=1 SV=3 4.09 3578.1 - 225359 - - - -0.4001 - 2.586 0.601 - 108.7 1 1 0 -0.001 24 0 0 0 5.65E+06 4.34E+06 - - - 7.447 0.9998 221125_WJC_METTL3_EV_vs_WT_F08.22044.22044.4 1.73E-07 12/132 K.HSSVYPTQEELEAVQNMVSHTER[166.11].A "sp|Q12906|ILF3_HUMAN,tr|K7EM82|K7EM82_HUMAN,tr|K7ER69|K7ER69_HUMAN,tr|K7ENK6|K7ENK6_HUMAN,tr|K7EJ09|K7EJ09_HUMAN,tr|K7ERM6|K7ERM6_HUMAN,tr|K7EKJ9|K7EKJ9_HUMAN" 7 2680.2427 1.56 122739 22044 4 2680.256141 671.0679 Interleukin enhancer-binding factor 3 OS=Homo sapiens OX=9606 GN=ILF3 PE=1 SV=3 4.87 3578.3 - 132377 - - - 5.0283 - 2.837 0.579 - 79.4 1 2 0 0.0135 23 0 0 0 3.93E+07 2.53E+07 - - - 4.5997 1 221125_WJC_METTL3_EV_vs_WT_F08.22048.22048.4 1.13E-10 26/120 K.EEYITSALESTEEKLHDAASK.L "sp|P52732|KIF11_HUMAN,tr|A0A7I2YQY4|A0A7I2YQY4_HUMAN,tr|A0A7I2V3A9|A0A7I2V3A9_HUMAN,tr|A0A7I2V3V3|A0A7I2V3V3_HUMAN" 4 2350.1176 6.38 122741 22048 4 2350.127305 588.5367 Kinesin-like protein KIF11 OS=Homo sapiens OX=9606 GN=KIF11 PE=1 SV=2 4.41 3578.8 - 1.82E+06 - - - 4.1228 - 4.974 0.654 - 826.9 1 2 1 0.0097 21 0 0 0 2.31E+07 3.63E+06 - - - 5.4462 0.9987 221125_WJC_METTL3_EV_vs_WT_F08.22049.22049.4 4.93E-07 13/126 K.NTTYDLIANIVHDGKPSEGSYR.L "sp|Q53GS9|SNUT2_HUMAN,tr|B9A018|B9A018_HUMAN,tr|A0A087X1B2|A0A087X1B2_HUMAN" 3 2449.1874 1.42 122742 22049 4 2449.202122 613.3041 U4\U6.U5 tri-snRNP-associated protein 2 OS=Homo sapiens OX=9606 GN=USP39 PE=1 SV=2 5.38 3578.9 - 282837 - - - 6.0244 - 2.809 0.473 - 59.3 1 2 0 0.0148 22 0 0 0 2.87E+06 2.02E+06 - - - 3.6769 1 221125_WJC_METTL3_EV_vs_WT_F08.22050.22050.4 5.97E-10 22/132 K.HSSVYPTQEELEAVQNMVSHTER.A "sp|Q12906|ILF3_HUMAN,tr|K7EM82|K7EM82_HUMAN,tr|K7ER69|K7ER69_HUMAN,tr|K7ENK6|K7ENK6_HUMAN,tr|K7EJ09|K7EJ09_HUMAN,tr|K7ERM6|K7ERM6_HUMAN,tr|K7EKJ9|K7EKJ9_HUMAN" 7 2670.2344 1.56 122743 22050 4 2670.250009 668.5659 Interleukin enhancer-binding factor 3 OS=Homo sapiens OX=9606 GN=ILF3 PE=1 SV=3 4.87 3579.1 - 309258 - - - 5.8478 - 4.266 0.636 - 269.5 1 2 0 0.0156 23 0 0 0 3.94E+07 2.53E+07 - - - 5.2274 0.9977 221125_WJC_METTL3_EV_vs_WT_F08.22058.22058.3 2.11E-07 Dec-68 K.LVINGNPITIFQERDPSK.L sp|P04406|G3P_HUMAN 1 2040.1004 1.04 122749 22058 3 2040.111834 681.0407 Glyceraldehyde-3-phosphate dehydrogenase OS=Homo sapiens OX=9606 GN=GAPDH PE=1 SV=3 6.07 3580.1 - 315843 - - - 5.6095 - 2.58 0.553 - 137.5 1 2 1 0.0114 18 0 0 0 2.33E+07 2.24E+07 - - - 7.0623 1 221125_WJC_METTL3_EV_vs_WT_F08.22059.22059.3 6.99E-11 16/56 K.HSGNITFDEIVNIAR.Q sp|P30050|RL12_HUMAN 1 1684.8533 1.21 122750 22059 3 1684.859049 562.625 60S ribosomal protein L12 OS=Homo sapiens OX=9606 GN=RPL12 PE=1 SV=1 5.32 3580.3 - 200207 - - - 3.4223 - 3.092 0.621 - 463.9 1 2 0 0.0058 15 0 0 0 5.63E+06 4.66E+06 - - - 8.4074 0.9993 221125_WJC_METTL3_EV_vs_WT_F08.22063.22063.3 4.14E-05 Dec-68 K.LVINGNPITIFQER[166.11]DPSK[136.11].L sp|P04406|G3P_HUMAN 1 2058.1229 1.04 122752 22063 3 2058.127421 687.0482 Glyceraldehyde-3-phosphate dehydrogenase OS=Homo sapiens OX=9606 GN=GAPDH PE=1 SV=3 6.07 3580.8 - 407575 - - - 2.2161 - 2.501 0.429 - 132 1 2 1 0.0046 18 0 0 0 2.33E+07 2.25E+07 - - - 5.6043 0.9908 221125_WJC_METTL3_EV_vs_WT_F08.22065.22065.4 0.00139 7/168 R.NITNNADIQQMNR[166.11]PSNVAHILQTLSAPTK[136.11].N sp|Q6ZW49|PAXI1_HUMAN 1 3206.6585 2.86 122754 22065 4 3206.671843 802.6719 PAX-interacting protein 1 OS=Homo sapiens OX=9606 GN=PAXIP1 PE=1 SV=2 8.75 3581.1 - 141164 - - - 4.1567 - 1.894 0.291 - 20.2 1 2 0 0.0133 29 0 0 0 5.54E+06 1.93E+06 - - - 1.952 0.9991 221125_WJC_METTL3_EV_vs_WT_F08.22068.22068.3 0.00167 8/128 R.SDSPVPTAPTSGGPK[136.11]PSTASAVPELATDPELEK[136.11].K "sp|Q86U44|MTA70_HUMAN,tr|B4E349|B4E349_HUMAN,tr|F5H6D8|F5H6D8_HUMAN,tr|B4DTN4|B4DTN4_HUMAN" 4 3248.6271 0.001 122755 22068 3 3248.627869 1083.883 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 4.18 3581.5 - 212690 - - - 0.2373 - 1.779 0.314 - 31.2 1 2 0 0.0008 33 0 0 0 0.00E+00 1.53E+07 - - - 3.3659 1 221125_WJC_METTL3_EV_vs_WT_F08.22076.22076.4 1.10E-09 16/246 K.NTPLSEDDNPGASSAPAQATFISPSEDFSSSSQAEVPPSLSR.S sp|Q9BT25|HAUS8_HUMAN 1 4276.952 2.9 122760 22076 4 4276.970017 1070.2453 HAUS augmin-like complex subunit 8 OS=Homo sapiens OX=9606 GN=HAUS8 PE=1 SV=3 3.71 3582.5 - 206580 - - - 4.2093 - 3.093 0.688 - 38.8 1 2 0 0.018 42 0 0 0 3.35E+06 1.16E+06 - - - 5.5322 1 221125_WJC_METTL3_EV_vs_WT_F08.22078.22078.3 2.13E-12 23/88 K.HSSVYPTQEELEAVQNMVSHTER.A "sp|Q12906|ILF3_HUMAN,tr|K7EM82|K7EM82_HUMAN,tr|K7ER69|K7ER69_HUMAN,tr|K7ENK6|K7ENK6_HUMAN,tr|K7EJ09|K7EJ09_HUMAN,tr|K7ERM6|K7ERM6_HUMAN,tr|K7EKJ9|K7EKJ9_HUMAN" 7 2670.2344 1.16 122761 22078 3 2670.231717 891.0854 Interleukin enhancer-binding factor 3 OS=Homo sapiens OX=9606 GN=ILF3 PE=1 SV=3 4.87 3582.8 - 256652 - - - -1.0025 - 4.595 0.708 - 675.9 1 2 0 -0.0027 23 0 0 0 9.12E+06 7.89E+06 - - - 10.0103 0.9986 221125_WJC_METTL3_EV_vs_WT_F08.22080.22080.4 5.53E-05 9/108 K.NTHATTHNAYDLEVIDIFK.L "sp|P09874|PARP1_HUMAN,tr|A0A7I2V3E1|A0A7I2V3E1_HUMAN" 2 2201.0753 1.24 122763 22080 4 2201.083898 551.2761 Poly [ADP-ribose] polymerase 1 OS=Homo sapiens OX=9606 GN=PARP1 PE=1 SV=4 5.21 3583 - 347614 - - - 3.9076 - 1.639 0.385 - 47.5 1 2 0 0.0086 19 0 0 0 8.23E+06 6.64E+06 - - - 2.7418 0.9999 221125_WJC_METTL3_EV_vs_WT_F08.22087.22087.4 6.87E-07 11/180 R.QYQHGSVSDTVFDSIPANPALLTYPRPGTSR.S sp|Q99959|PKP2_HUMAN 1 3373.6691 2.09 122768 22087 4 3373.68121 844.4246 Plakophilin-2 OS=Homo sapiens OX=9606 GN=PKP2 PE=1 SV=2 6.75 3584 - 291273 - - - 3.5842 - 2.014 0.564 - 19 1 2 0 0.0121 31 0 0 0 1.25E+07 5.98E+06 - - - 4.3445 0.9972 221125_WJC_METTL3_EV_vs_WT_F08.22091.22091.4 2.40E-05 11/150 K.VEEQEPELTSTPNFVVEVIK[136.11]NDDGK[136.11]K[136.11].A "sp|Q07021|C1QBP_HUMAN,tr|I3L3B0|I3L3B0_HUMAN,tr|I3L3Q7|I3L3Q7_HUMAN" 3 2967.5139 1.57 122770 22091 4 2967.514351 742.8858 "Complement component 1 Q subcomponent-binding protein, mitochondrial OS=Homo sapiens OX=9606 GN=C1QBP PE=1 SV=1" 4.25 3584.6 - 329365 - - - 0.1476 - 2.626 0.308 - 58.9 1 2 1 0.0004 26 0 0 0 6.68E+06 4.27E+06 - - - 2.2113 1 221125_WJC_METTL3_EV_vs_WT_F08.22099.22099.4 4.18E-07 16/180 R.QYQHGSVSDTVFDSIPANPALLTYPR[166.11]PGTSR[166.11].S sp|Q99959|PKP2_HUMAN 1 3393.6857 2.12 122776 22099 4 3393.694743 849.4287 Plakophilin-2 OS=Homo sapiens OX=9606 GN=PKP2 PE=1 SV=2 6.75 3585.6 - 326114 - - - 2.677 - 2.57 0.63 - 58.4 1 2 0 0.0091 31 0 0 0 1.29E+07 6.11E+06 - - - 4.9939 1 221125_WJC_METTL3_EV_vs_WT_F08.22106.22106.3 6.55E-12 25/100 K.EQVHQGGVELQQLEAGLQEAGEEDTR.L "sp|Q8NBT2|SPC24_HUMAN,tr|K7EJH0|K7EJH0_HUMAN,tr|K7EMX1|K7EMX1_HUMAN,tr|K7EJV2|K7EJV2_HUMAN,tr|K7ESQ2|K7ESQ2_HUMAN" 5 2849.3428 2.65 122781 22106 3 2849.34512 950.7882 Kinetochore protein Spc24 OS=Homo sapiens OX=9606 GN=SPC24 PE=1 SV=2 4.06 3586.6 - 1.26E+06 - - - 0.829 - 4.898 0.656 - 636.6 1 2 0 0.0024 26 0 0 0 6.16E+07 2.32E+07 - - - 9.5084 0.9149 221125_WJC_METTL3_EV_vs_WT_F08.22111.22111.2 0.0363 16-Sep L.NSLIAHAHR.R "sp|Q16891|MIC60_HUMAN,tr|B9A067|B9A067_HUMAN,tr|C9J406|C9J406_HUMAN,tr|H7C463|H7C463_HUMAN" 4 1017.5468 1.16 122785 22111 2 1017.54911 509.7807 MICOS complex subunit MIC60 OS=Homo sapiens OX=9606 GN=IMMT PE=1 SV=1 9.76 3587.2 - 81244.6 - - - 2.2594 - 1.972 0.257 - 300.9 1 1 0 0.0023 9 0 0 0 3.95E+06 3.41E+06 - - - 2.903 1 221125_WJC_METTL3_EV_vs_WT_F08.22116.22116.3 6.52E-16 31/100 K.EQVHQGGVELQQLEAGLQEAGEEDTR[166.11].L "sp|Q8NBT2|SPC24_HUMAN,tr|K7EJH0|K7EJH0_HUMAN,tr|K7EMX1|K7EMX1_HUMAN,tr|K7EJV2|K7EJV2_HUMAN,tr|K7ESQ2|K7ESQ2_HUMAN" 5 2859.351 2.65 122788 22116 3 2859.356284 954.1243 Kinetochore protein Spc24 OS=Homo sapiens OX=9606 GN=SPC24 PE=1 SV=2 4.06 3587.9 - 1.18E+06 - - - 1.8382 - 5.537 0.733 - 1224.4 1 2 0 0.0053 26 0 0 0 6.16E+07 2.32E+07 - - - 10.6482 1 221125_WJC_METTL3_EV_vs_WT_F08.22124.22124.4 2.38E-10 21/150 K.EQVHQGGVELQQLEAGLQEAGEEDTR.L "sp|Q8NBT2|SPC24_HUMAN,tr|K7EJH0|K7EJH0_HUMAN,tr|K7EMX1|K7EMX1_HUMAN,tr|K7EJV2|K7EJV2_HUMAN,tr|K7ESQ2|K7ESQ2_HUMAN" 5 2849.3428 2.71 122794 22124 4 2849.346441 713.343 Kinetochore protein Spc24 OS=Homo sapiens OX=9606 GN=SPC24 PE=1 SV=2 4.06 3588.9 - 649471 - - - 1.2926 - 4.022 0.581 - 166.5 1 2 0 0.0037 26 0 0 0 5.94E+06 2.20E+06 - - - 4.721 1 221125_WJC_METTL3_EV_vs_WT_F08.22125.22125.4 4.49E-09 15/108 K.NTHATTHNAYDLEVIDIFK[136.11].L "sp|P09874|PARP1_HUMAN,tr|A0A7I2V3E1|A0A7I2V3E1_HUMAN" 2 2209.0895 1.25 122795 22125 4 2209.090036 553.2797 Poly [ADP-ribose] polymerase 1 OS=Homo sapiens OX=9606 GN=PARP1 PE=1 SV=4 5.21 3589.1 - 344744 - - - 0.244 - 3.085 0.563 - 170.9 1 2 0 0.0005 19 0 0 0 8.54E+06 6.83E+06 - - - 4.5073 0.9354 221125_WJC_METTL3_EV_vs_WT_F08.22126.22126.2 0.00372 26-Jul K.LLHHLSDLALTLPT.D "sp|Q86U44|MTA70_HUMAN,tr|B4E349|B4E349_HUMAN,tr|F5H6D8|F5H6D8_HUMAN,tr|H0YFV6|H0YFV6_HUMAN,tr|B4DTN4|B4DTN4_HUMAN" 5 1542.877 - 122796 22126 2 1542.876296 772.4458 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 5.97 3589.2 - 182870 - - - -0.4427 - 1.815 0.234 - 87.2 1 1 0 -0.0007 14 0 0 0 - - - - - 2.265 0.9999 221125_WJC_METTL3_EV_vs_WT_F08.22129.22129.3 1.53E-06 Oct-96 K.QYNGVPLDGRPMNIQLVTSQIDAQR.R "sp|Q86V81|THOC4_HUMAN,tr|E9PB61|E9PB61_HUMAN" 2 2812.429 0.58 122797 22129 3 2812.435959 938.4836 THO complex subunit 4 OS=Homo sapiens OX=9606 GN=ALYREF PE=1 SV=3 5.96 3589.6 - 328814 - - - 2.4705 - 1.991 0.507 - 38.1 1 2 0 0.0069 25 0 0 0 9.50E+06 1.63E+07 - - - 5.7749 0.9999 221125_WJC_METTL3_EV_vs_WT_F08.22131.22131.3 0.000425 Dec-96 K.QYNGVPLDGR[166.11]PMNIQLVTSQIDAQR[166.11].R "sp|Q86V81|THOC4_HUMAN,tr|E9PB61|E9PB61_HUMAN" 2 2832.4456 0.58 122798 22131 3 2832.44806 945.1558 THO complex subunit 4 OS=Homo sapiens OX=9606 GN=ALYREF PE=1 SV=3 5.96 3589.8 - 457698 - - - 0.8858 - 2.156 0.475 - 59 1 2 0 0.0025 25 0 0 0 9.50E+06 1.63E+07 - - - 5.6026 1 221125_WJC_METTL3_EV_vs_WT_F08.22133.22133.3 1.73E-09 24/80 R.K[136.11]HAASDVDLEIESLLNQQSTK[136.11].E "sp|Q86U44|MTA70_HUMAN,tr|F5H6D8|F5H6D8_HUMAN,tr|H0YFV6|H0YFV6_HUMAN,tr|B4DTN4|B4DTN4_HUMAN" 4 2341.2096 0.15 122799 22133 3 2342.208904 781.4105 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 4.75 3590.1 - 1.53E+06 - - - 426.8242 - 4.471 0.595 - 863 1 2 0 0.9993 21 0 0 0 3.39E+07 2.21E+08 - - - 8.4873 1 221125_WJC_METTL3_EV_vs_WT_F08.22138.22138.4 1.93E-06 9/150 K.EQVHQGGVELQQLEAGLQEAGEEDTR[166.11].L "sp|Q8NBT2|SPC24_HUMAN,tr|K7EJH0|K7EJH0_HUMAN,tr|K7EMX1|K7EMX1_HUMAN,tr|K7EJV2|K7EJV2_HUMAN,tr|K7ESQ2|K7ESQ2_HUMAN" 5 2859.351 2.7 122803 22138 4 2859.354686 715.845 Kinetochore protein Spc24 OS=Homo sapiens OX=9606 GN=SPC24 PE=1 SV=2 4.06 3590.7 - 196546 - - - 1.2793 - 2.554 0.517 - 31.5 1 2 0 0.0037 26 0 0 0 6.03E+06 2.23E+06 - - - 4.0207 0.9998 221125_WJC_METTL3_EV_vs_WT_F08.22139.22139.2 8.39E-07 Sep-34 K.SSGPTSLFAVTVAPPGAR[166.11].Q "sp|Q00839|HNRPU_HUMAN,tr|A0A1W2PP35|A0A1W2PP35_HUMAN,tr|A0A1W2PPS1|A0A1W2PPS1_HUMAN,tr|A0A1W2PP22|A0A1W2PP22_HUMAN,tr|A0A1X7SBS1|A0A1X7SBS1_HUMAN" 5 1723.9133 0.84 122804 22139 2 1723.91611 862.9639 Heterogeneous nuclear ribonucleoprotein U OS=Homo sapiens OX=9606 GN=HNRNPU PE=1 SV=6 9.47 3590.8 - 145644 - - - 1.6567 - 2.13 0.529 - 218.4 1 2 0 0.0029 18 0 0 0 4.13E+06 4.95E+06 - - - 4.8063 0.9518 221125_WJC_METTL3_EV_vs_WT_F08.22140.22140.3 0.0485 Jul-68 K.SSGPTSLFAVTVAPPGAR.Q "sp|Q00839|HNRPU_HUMAN,tr|A0A1W2PP35|A0A1W2PP35_HUMAN,tr|A0A1W2PPS1|A0A1W2PPS1_HUMAN,tr|A0A1W2PP22|A0A1W2PP22_HUMAN,tr|A0A1X7SBS1|A0A1X7SBS1_HUMAN" 5 1713.905 1.26 122805 22140 3 1713.909638 572.3089 Heterogeneous nuclear ribonucleoprotein U OS=Homo sapiens OX=9606 GN=HNRNPU PE=1 SV=6 9.47 3590.9 - 127554 - - - 2.7154 - 1.423 0.202 - 36.7 2 2 0 0.0047 18 0 0 0 3.50E+06 2.78E+06 - - - 1.5299 0.9655 221125_WJC_METTL3_EV_vs_WT_F08.22141.22141.4 0.000763 10/114 Q.HRGDADQASNILASFGLSAR.D "sp|P43243|MATR3_HUMAN,tr|A8MXP9|A8MXP9_HUMAN,tr|D6R991|D6R991_HUMAN,tr|A0A0R4J2E8|A0A0R4J2E8_HUMAN,tr|D6REM6|D6REM6_HUMAN" 5 2085.0352 2.47 122806 22141 4 2085.039406 522.2661 Matrin-3 OS=Homo sapiens OX=9606 GN=MATR3 PE=1 SV=2 6.75 3591.1 - 96203.3 - - - 2.0345 - 2.408 0.48 - 83.6 1 1 1 0.0042 20 0 0 0 1.12E+07 4.55E+06 - - - 3.6965 1 221125_WJC_METTL3_EV_vs_WT_F08.22143.22143.4 4.70E-06 10/252 K.VVGSAVGSGSITSNIVASNSLPPATIAPPKPASWADIASKPAK.Q sp|Q9Y5A9|YTHD2_HUMAN 1 4113.211 2.71 122807 22143 4 4113.21127 1029.31 YTH domain-containing family protein 2 OS=Homo sapiens OX=9606 GN=YTHDF2 PE=1 SV=2 9.7 3591.3 - 198835 - - - 0.0632 - 2.365 0.503 - 15.4 1 2 0 0.0003 43 0 0 0 4.59E+06 1.69E+06 - - - 3.849 0.9926 221125_WJC_METTL3_EV_vs_WT_F08.22145.22145.2 6.65E-07 Dec-40 C.LAISTPDAPATQDGVESLLQK[136.11].F "sp|Q86U44|MTA70_HUMAN,tr|B4E349|B4E349_HUMAN,tr|F5H6D8|F5H6D8_HUMAN,tr|H0YFV6|H0YFV6_HUMAN,tr|B4DTN4|B4DTN4_HUMAN" 5 2161.1358 0.001 122808 22145 2 2161.135914 1081.5752 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 4.03 3591.5 - 201568 - - - 0.0625 - 2.376 0.494 - 298.1 1 1 0 0.0001 21 0 0 0 0.00E+00 3.10E+06 - - - 4.8173 1 221125_WJC_METTL3_EV_vs_WT_F08.22165.22165.3 6.12E-05 14/100 R.DGAPQPPPPPPPPPPPMPLQLEAHLR.S sp|Q9ULL5|PRR12_HUMAN 1 2742.4316 14.63 122820 22165 3 2742.436259 915.1511 Proline-rich protein 12 OS=Homo sapiens OX=9606 GN=PRR12 PE=1 SV=3 5.32 3594.2 - 136209 - - - 1.7072 - 3.608 0.585 - 172.2 1 2 0 0.0047 26 0 0 0 4.13E+06 2.82E+05 - - - 8.0129 0.7797 221125_WJC_METTL3_EV_vs_WT_F08.22166.22166.4 5.14E-07 13/114 Q.HR[166.11]GDADQASNILASFGLSAR[166.11].D "sp|P43243|MATR3_HUMAN,tr|A8MXP9|A8MXP9_HUMAN,tr|D6R991|D6R991_HUMAN,tr|A0A0R4J2E8|A0A0R4J2E8_HUMAN,tr|D6REM6|D6REM6_HUMAN" 5 2105.0517 2.55 122821 22166 4 2105.06491 527.2702 Matrin-3 OS=Homo sapiens OX=9606 GN=MATR3 PE=1 SV=2 6.75 3594.4 - 53935.7 - - - 6.2735 - 2.551 0.57 - 148.6 1 1 1 0.0132 20 0 0 0 1.12E+07 4.38E+06 - - - 4.4967 0.8743 221125_WJC_METTL3_EV_vs_WT_F08.22179.22179.3 1.08E-05 Oct-80 C.LAISTPDAPATQDGVESLLQK[136.11].F "sp|Q86U44|MTA70_HUMAN,tr|B4E349|B4E349_HUMAN,tr|F5H6D8|F5H6D8_HUMAN,tr|H0YFV6|H0YFV6_HUMAN,tr|B4DTN4|B4DTN4_HUMAN" 5 2161.1358 0 122828 22179 3 2162.14049 721.3859 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 4.03 3596.1 - 142128 - - - 464.8995 - 2.412 0.497 - 128.8 1 1 0 1.0047 21 0 0 0 2.62E+04 2.51E+07 - - - 5.9136 0.9227 221125_WJC_METTL3_EV_vs_WT_F08.22180.22180.3 7.68E-08 12/128 K.RK[136.11]ELEQVC[160.03]NPIISGLYQGAGGPGPGGFGAQGPK[136.11].G "sp|P0DMV8|HS71A_HUMAN,sp|P0DMV9|HS71B_HUMAN,tr|V9GZ37|V9GZ37_HUMAN,tr|A0A0G2JIW1|A0A0G2JIW1_HUMAN" 4 3354.7114 - 122829 22180 3 3355.693689 1119.2444 Heat shock 70 kDa protein 1A OS=Homo sapiens OX=9606 GN=HSPA1A PE=1 SV=1 8.18 3596.3 - 215196 - - - 292.8106 - 2.907 0.599 - 111.5 1 2 1 0.9823 33 0 0 0 - - - - - 7.4012 0.9528 221125_WJC_METTL3_EV_vs_WT_F08.22211.22211.4 0.00893 7/216 R.QSFAASHQLPGYAPTPQPTGLSGIFDTSVNSASSNTK[136.11].E tr|A0A3B3IRW6|A0A3B3IRW6_HUMAN 1 3770.8267 1.51 122847 22211 4 3770.839881 943.714 Glutamine and serine-rich protein 1 OS=Homo sapiens OX=9606 GN=QSER1 PE=1 SV=1 6.74 3600.6 - 179991 - - - 3.4828 - 1.837 0.199 - 18.7 1 2 0 0.0131 37 0 0 0 6.03E+06 3.99E+06 - - - 1.1327 0.9806 221125_WJC_METTL3_EV_vs_WT_F08.22218.22218.2 0.0169 22-Jun K.SLESLDTSLFAK.N sp|Q12874|SF3A3_HUMAN 1 1309.6765 24.23 122850 22218 2 1309.681791 655.8456 Splicing factor 3A subunit 3 OS=Homo sapiens OX=9606 GN=SF3A3 PE=1 SV=1 4.37 3601.6 - 109275 - - - 4.0033 - 1.175 0.312 - 74.2 1 2 0 0.0052 12 0 0 0 1.74E+06 7.19E+04 - - - 1.7681 1 221125_WJC_METTL3_EV_vs_WT_F08.22239.22239.2 7.61E-06 Dec-32 R.AAVEEGIVLGGGC[160.03]ALLR[166.11].C "sp|P10809|CH60_HUMAN,tr|A0A7I2V2X6|A0A7I2V2X6_HUMAN,tr|A0A7I2YQK6|A0A7I2YQK6_HUMAN,tr|A0A7I2V599|A0A7I2V599_HUMAN" 4 1693.9061 1.56 122862 22239 2 1693.908107 847.9603 "60 kDa heat shock protein, mitochondrial OS=Homo sapiens OX=9606 GN=HSPD1 PE=1 SV=2" 4.53 3604.5 - 112153 - - - 1.2079 - 3.217 0.527 - 369.3 1 2 0 0.002 17 0 0 0 3.69E+06 2.36E+06 - - - 5.8055 0.9999 221125_WJC_METTL3_EV_vs_WT_F08.22241.22241.3 8.83E-06 Aug-52 K.K[136.11]GPGEVAGTVTGQK[136.11].R "sp|Q86U44|MTA70_HUMAN,tr|F5H6D8|F5H6D8_HUMAN,tr|H0YFV6|H0YFV6_HUMAN,tr|B4DTN4|B4DTN4_HUMAN" 4 1343.738 0 122864 22241 3 1343.740041 448.9199 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 8.59 3604.7 - 112263 - - - 1.5345 - 1.88 0.509 - 79.6 1 2 0 0.0021 14 0 0 0 1.27E+04 5.17E+06 - - - 5.8919 1 221125_WJC_METTL3_EV_vs_WT_F08.22246.22246.3 1.28E-08 13/72 K.IIAATIENAQPILQIDNAR.L sp|P08779|K1C16_HUMAN 1 2063.1375 60.57 122867 22246 3 2063.13923 688.7198 "Keratin, type I cytoskeletal 16 OS=Homo sapiens OX=9606 GN=KRT16 PE=1 SV=4" 4.37 3605.4 - 208420 - - - 0.8366 - 2.671 0.6 - 170.7 1 2 0 0.0017 19 0 0 0 1.57E+07 2.59E+05 - - - 7.6426 0.9997 221125_WJC_METTL3_EV_vs_WT_F08.22252.22252.4 2.64E-11 23/162 K.EQVHQGGVELQQLEAGLQEAGEEDTRLK.A "sp|Q8NBT2|SPC24_HUMAN,tr|K7EJH0|K7EJH0_HUMAN,tr|K7EMX1|K7EMX1_HUMAN,tr|K7EJV2|K7EJV2_HUMAN,tr|K7ESQ2|K7ESQ2_HUMAN" 5 3090.5218 2.39 122870 22252 4 3090.533548 773.6377 Kinetochore protein Spc24 OS=Homo sapiens OX=9606 GN=SPC24 PE=1 SV=2 4.3 3606.2 - 199746 - - - 3.8062 - 4.459 0.614 - 254.9 1 2 1 0.0118 28 0 0 0 5.85E+07 2.45E+07 - - - 5.0311 0.9977 221125_WJC_METTL3_EV_vs_WT_F08.22261.22261.4 0.000542 9/126 K.C[160.03]QEVISWLDANTLAEK[136.11]DEFEHK[136.11].R "sp|P0DMV8|HS71A_HUMAN,sp|P0DMV9|HS71B_HUMAN,tr|V9GZ37|V9GZ37_HUMAN,tr|A0A0G2JIW1|A0A0G2JIW1_HUMAN" 4 2677.2665 0.03 122874 22261 4 2677.27254 670.3239 Heat shock 70 kDa protein 1A OS=Homo sapiens OX=9606 GN=HSPA1A PE=1 SV=1 4.35 3607.5 - 175603 - - - 2.2628 - 1.951 0.361 - 37.2 1 2 1 0.0061 22 0 0 0 1.30E+05 5.03E+06 - - - 2.5851 0.9999 221125_WJC_METTL3_EV_vs_WT_F08.22263.22263.4 0.000194 9/138 K.ENSTASEVLDSLSQSVHVK[136.11]PENLR[166.11].L "sp|O94966|UBP19_HUMAN,tr|E7ESU0|E7ESU0_HUMAN" 2 2656.3423 0.27 122875 22263 4 2656.344461 665.0929 Ubiquitin carboxyl-terminal hydrolase 19 OS=Homo sapiens OX=9606 GN=USP19 PE=1 SV=2 4.83 3607.7 - 187556 - - - 0.8105 - 2.205 0.418 - 58.8 1 2 0 0.0022 24 0 0 0 2.27E+06 8.53E+06 - - - 3.1175 0.998 221125_WJC_METTL3_EV_vs_WT_F08.22264.22264.2 9.93E-08 13/32 R.AAVEEGIVLGGGC[160.03]ALLR.C "sp|P10809|CH60_HUMAN,tr|A0A7I2V2X6|A0A7I2V2X6_HUMAN,tr|A0A7I2YQK6|A0A7I2YQK6_HUMAN,tr|A0A7I2V599|A0A7I2V599_HUMAN" 4 1683.8978 1.56 122876 22264 2 1683.906038 842.9562 "60 kDa heat shock protein, mitochondrial OS=Homo sapiens OX=9606 GN=HSPD1 PE=1 SV=2" 4.53 3607.9 - 102240 - - - 4.8976 - 2.897 0.464 - 456.9 1 2 0 0.0082 17 0 0 0 3.69E+06 2.36E+06 - - - 5.0806 0.9999 221125_WJC_METTL3_EV_vs_WT_F08.22271.22271.4 9.08E-11 27/162 K.EQVHQGGVELQQLEAGLQEAGEEDTR[166.11]LK[136.11].A "sp|Q8NBT2|SPC24_HUMAN,tr|K7EJH0|K7EJH0_HUMAN,tr|K7EMX1|K7EMX1_HUMAN,tr|K7EJV2|K7EJV2_HUMAN,tr|K7ESQ2|K7ESQ2_HUMAN" 5 3108.5443 2.39 122880 22271 4 3108.546547 778.1433 Kinetochore protein Spc24 OS=Homo sapiens OX=9606 GN=SPC24 PE=1 SV=2 4.3 3608.8 - 401246 - - - 0.7373 - 5.182 0.608 - 478.4 1 2 1 0.0023 28 0 0 0 5.85E+07 2.45E+07 - - - 5.0282 1 221125_WJC_METTL3_EV_vs_WT_F08.22286.22286.4 1.22E-08 11/162 K.TSPKPAVVETVTTAKPQQIQALMDEVTK.Q "sp|P56192|SYMC_HUMAN,tr|H0YIP0|H0YIP0_HUMAN,tr|H0YI94|H0YI94_HUMAN" 3 3009.6056 0.91 122888 22286 4 3009.611789 753.4087 "Methionine--tRNA ligase, cytoplasmic OS=Homo sapiens OX=9606 GN=MARS1 PE=1 SV=2" 5.85 3610.8 - 169021 - - - 2.0438 - 2.986 0.605 - 64.3 1 2 0 0.0062 28 0 0 0 2.66E+07 2.93E+07 - - - 4.8299 1 221125_WJC_METTL3_EV_vs_WT_F08.22287.22287.3 1.60E-09 10/124 R.K[136.11]INSSPNVNTTASGVEDLNIIQVTIPDDDNER[166.11].L "sp|P78347|GTF2I_HUMAN,tr|A0A494C1K3|A0A494C1K3_HUMAN" 2 3485.7241 1.75 122889 22287 3 3485.73045 1162.9153 General transcription factor II-I OS=Homo sapiens OX=9606 GN=GTF2I PE=1 SV=2 3.96 3610.9 - 115456 - - - 1.8303 - 2.473 0.633 - 47.9 1 2 0 0.0064 32 0 0 0 3.66E+08 2.09E+08 - - - 7.6786 1 221125_WJC_METTL3_EV_vs_WT_F08.22289.22289.4 2.69E-10 21/132 R.KTSQLLETLNQLSTHTHVVDITR.T "sp|Q14203|DCTN1_HUMAN,tr|A0A804CDA6|A0A804CDA6_HUMAN,tr|E7EX90|E7EX90_HUMAN,tr|A0A7P0Z4C3|A0A7P0Z4C3_HUMAN,tr|E7EWF7|E7EWF7_HUMAN" 5 2633.4137 1.69 122891 22289 4 2633.419437 659.3607 Dynactin subunit 1 OS=Homo sapiens OX=9606 GN=DCTN1 PE=1 SV=3 6.92 3611.2 - 412416 - - - 2.1865 - 4.417 0.628 - 483.4 1 2 0 0.0058 23 0 0 0 2.28E+08 1.35E+08 - - - 5.1718 1 221125_WJC_METTL3_EV_vs_WT_F08.22294.22294.4 2.60E-14 27/132 R.K[136.11]TSQLLETLNQLSTHTHVVDITR[166.11].T "sp|Q14203|DCTN1_HUMAN,tr|A0A804CDA6|A0A804CDA6_HUMAN,tr|E7EX90|E7EX90_HUMAN,tr|A0A7P0Z4C3|A0A7P0Z4C3_HUMAN,tr|E7EWF7|E7EWF7_HUMAN" 5 2651.4361 1.69 122893 22294 4 2651.436601 663.8663 Dynactin subunit 1 OS=Homo sapiens OX=9606 GN=DCTN1 PE=1 SV=3 6.92 3611.9 - 359954 - - - 0.1705 - 5.296 0.563 - 789.4 1 2 0 0.0005 23 0 0 0 2.28E+08 1.35E+08 - - - 4.6663 1 221125_WJC_METTL3_EV_vs_WT_F08.22295.22295.3 1.97E-16 23/124 R.KINSSPNVNTTASGVEDLNIIQVTIPDDDNER.L "sp|P78347|GTF2I_HUMAN,tr|A0A494C1K3|A0A494C1K3_HUMAN" 2 3467.7016 1.75 122894 22295 3 3467.70241 1156.9078 General transcription factor II-I OS=Homo sapiens OX=9606 GN=GTF2I PE=1 SV=2 3.96 3612 - 307820 - - - 0.2336 - 4.285 0.728 - 222.1 1 2 0 0.0008 32 0 0 0 3.65E+08 2.09E+08 - - - 10.004 0.9999 221125_WJC_METTL3_EV_vs_WT_F08.22296.22296.3 1.68E-07 13/128 R.SDSPVPTAPTSGGPK[136.11]PSTASAVPELATDPELEK[136.11].K "sp|Q86U44|MTA70_HUMAN,tr|B4E349|B4E349_HUMAN,tr|F5H6D8|F5H6D8_HUMAN,tr|B4DTN4|B4DTN4_HUMAN" 4 3248.6271 0.03 122895 22296 3 3248.637273 1083.883 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 4.18 3612.2 - 232552 - - - 3.1321 - 2.587 0.581 - 81.5 1 2 0 0.0102 33 0 0 0 1.45E+05 5.62E+06 - - - 7.2015 1 221125_WJC_METTL3_EV_vs_WT_F08.22300.22300.4 2.90E-08 16/186 R.KINSSPNVNTTASGVEDLNIIQVTIPDDDNER.L "sp|P78347|GTF2I_HUMAN,tr|A0A494C1K3|A0A494C1K3_HUMAN" 2 3467.7016 1.35 122897 22300 4 3467.708809 867.9327 General transcription factor II-I OS=Homo sapiens OX=9606 GN=GTF2I PE=1 SV=2 3.96 3612.7 - 279267 - - - 2.0789 - 3.493 0.675 - 74 1 2 0 0.0072 32 0 0 0 1.42E+08 1.06E+08 - - - 5.4769 0.9993 221125_WJC_METTL3_EV_vs_WT_F08.22307.22307.4 0.0137 8/108 R.FAHIDGDHLTLLNVYHAFK[136.11].Q sp|O43143|DHX15_HUMAN 1 2218.1415 1.07 122901 22307 4 2218.145472 555.5426 Pre-mRNA-splicing factor ATP-dependent RNA helicase DHX15 OS=Homo sapiens OX=9606 GN=DHX15 PE=1 SV=2 6.26 3613.7 - 186332 - - - 1.8029 - 1.697 0.338 - 36.5 1 2 0 0.004 19 0 0 0 3.75E+06 3.50E+06 - - - 2.3457 0.9201 221125_WJC_METTL3_EV_vs_WT_F08.22310.22310.4 0.0796 5/108 R.FAHIDGDHLTLLNVYHAFK.Q sp|O43143|DHX15_HUMAN 1 2210.1273 1.07 122903 22310 4 2210.135427 553.5391 Pre-mRNA-splicing factor ATP-dependent RNA helicase DHX15 OS=Homo sapiens OX=9606 GN=DHX15 PE=1 SV=2 6.26 3614 - 141519 - - - 3.6894 - 1.269 0.194 - 16.8 1 2 0 0.0082 19 0 0 0 3.75E+06 3.50E+06 - - - 0.9929 1 221125_WJC_METTL3_EV_vs_WT_F08.22322.22322.4 1.41E-16 28/162 K.TSPK[136.11]PAVVETVTTAK[136.11]PQQIQALMDEVTK[136.11].Q "sp|P56192|SYMC_HUMAN,tr|H0YIP0|H0YIP0_HUMAN,tr|H0YI94|H0YI94_HUMAN" 3 3033.6482 0.91 122909 22322 4 3033.648946 759.4193 "Methionine--tRNA ligase, cytoplasmic OS=Homo sapiens OX=9606 GN=MARS1 PE=1 SV=2" 5.85 3615.5 - 1.11E+06 - - - 0.2334 - 5.195 0.674 - 756.8 1 2 0 0.0007 28 0 0 0 2.66E+07 2.93E+07 - - - 5.6039 0.9998 221125_WJC_METTL3_EV_vs_WT_F08.22325.22325.3 9.86E-06 Sep-52 K.SLNNQFASFIDKVR.F sp|P04264|K2C1_HUMAN 1 1637.8526 123.85 122912 22325 3 1637.852593 546.9581 "Keratin, type II cytoskeletal 1 OS=Homo sapiens OX=9606 GN=KRT1 PE=1 SV=6" 8.46 3615.9 - 158765 - - - 0.0232 - 1.971 0.507 - 82 1 2 1 0 14 0 0 0 7.09E+06 5.73E+04 - - - 5.9958 0.9998 221125_WJC_METTL3_EV_vs_WT_F08.22328.22328.4 3.34E-06 12/162 R.QVASHVGLHSASIPGILALDLC[160.03]PSDTNK[136.11].L "sp|Q9UMS4|PRP19_HUMAN,tr|F5GY56|F5GY56_HUMAN" 2 2907.5004 1.73 122913 22328 4 2907.509233 727.8824 Pre-mRNA-processing factor 19 OS=Homo sapiens OX=9606 GN=PRPF19 PE=1 SV=1 5.98 3616.2 - 260374 - - - 3.0408 - 2.58 0.445 - 77.6 1 2 0 0.0088 28 0 0 0 2.12E+07 1.23E+07 - - - 3.3911 1 221125_WJC_METTL3_EV_vs_WT_F08.22330.22330.4 1.05E-14 24/150 K.VEEQEPELTSTPNFVVEVIK[136.11]NDDGK[136.11]K[136.11].A "sp|Q07021|C1QBP_HUMAN,tr|I3L3B0|I3L3B0_HUMAN,tr|I3L3Q7|I3L3Q7_HUMAN" 3 2967.5139 1.15 122914 22330 4 2967.518533 742.8858 "Complement component 1 Q subcomponent-binding protein, mitochondrial OS=Homo sapiens OX=9606 GN=C1QBP PE=1 SV=1" 4.25 3616.5 - 811184 - - - 1.5569 - 4.335 0.696 - 339 1 2 1 0.0046 26 0 0 0 8.16E+07 7.10E+07 - - - 5.7454 0.9995 221125_WJC_METTL3_EV_vs_WT_F08.22331.22331.3 1.52E-07 Nov-76 K.KQELEVLTANIQDLKEEYSR.K "sp|Q9HBM1|SPC25_HUMAN,tr|C9JW94|C9JW94_HUMAN" 2 2405.2438 2.74 122915 22331 3 2405.250116 802.7552 Kinetochore protein Spc25 OS=Homo sapiens OX=9606 GN=SPC25 PE=1 SV=1 4.59 3616.6 - 232512 - - - 2.618 - 2.493 0.5 - 117.7 1 2 1 0.0063 20 0 0 0 3.93E+06 1.43E+06 - - - 6.3289 0.9998 221125_WJC_METTL3_EV_vs_WT_F08.22334.22334.4 3.04E-07 16/114 K.KQELEVLTANIQDLKEEYSR.K "sp|Q9HBM1|SPC25_HUMAN,tr|C9JW94|C9JW94_HUMAN" 2 2405.2438 0.59 122918 22334 4 2405.249935 602.3182 Kinetochore protein Spc25 OS=Homo sapiens OX=9606 GN=SPC25 PE=1 SV=1 4.59 3617 - 365130 - - - 2.5428 - 3.222 0.533 - 170.9 1 2 1 0.0061 20 0 0 0 7.28E+06 1.23E+07 - - - 4.2547 0.9097 221125_WJC_METTL3_EV_vs_WT_F08.22345.22345.4 0.00192 13/234 R.GSDIKDLTVC[160.03]EPPKPQC[160.03]SLPQDPAIVQSSLGSSTSSFQSM.G "sp|Q8ND56|LS14A_HUMAN,tr|A0A140TA76|A0A140TA76_HUMAN,tr|K7EMZ9|K7EMZ9_HUMAN" 3 4278.013 1.3 122921 22345 4 4278.012929 1070.5105 Protein LSM14 homolog A OS=Homo sapiens OX=9606 GN=LSM14A PE=1 SV=3 4.23 3618.6 - 574074 - - - -0.0259 - 1.945 0.387 - 44.3 1 1 1 -0.0001 40 0 0 0 1.46E+07 1.13E+07 - - - 2.7865 1 221125_WJC_METTL3_EV_vs_WT_F08.22347.22347.4 5.94E-12 37/186 R.K[136.11]INSSPNVNTTASGVEDLNIIQVTIPDDDNER[166.11].L "sp|P78347|GTF2I_HUMAN,tr|A0A494C1K3|A0A494C1K3_HUMAN" 2 3485.7241 1.42 122922 22347 4 3485.719779 872.4383 General transcription factor II-I OS=Homo sapiens OX=9606 GN=GTF2I PE=1 SV=2 3.96 3618.8 - 2.55E+06 - - - -1.231 - 5.513 0.665 - 500.8 1 2 0 -0.0043 32 0 0 0 1.41E+08 9.95E+07 - - - 5.5284 0.9994 221125_WJC_METTL3_EV_vs_WT_F08.22353.22353.3 8.65E-05 Aug-96 K.EQASHLGGAVFSGAGNIAAATGLVK[136.11].R "sp|Q16143|SYUB_HUMAN,tr|G4Y816|G4Y816_HUMAN" 2 2333.2219 1.33 122924 22353 3 2333.214746 778.7479 Beta-synuclein OS=Homo sapiens OX=9606 GN=SNCB PE=1 SV=1 6.85 3619.7 - 195803 - - - -3.07 - 1.977 0.428 - 31.5 1 2 0 -0.0072 25 0 0 0 4.21E+06 3.16E+06 - - - 4.8779 1 221125_WJC_METTL3_EV_vs_WT_F08.22356.22356.4 2.12E-09 24/120 R.K[136.11]HAASDVDLEIESLLNQQSTK[136.11].E "sp|Q86U44|MTA70_HUMAN,tr|F5H6D8|F5H6D8_HUMAN,tr|H0YFV6|H0YFV6_HUMAN,tr|B4DTN4|B4DTN4_HUMAN" 4 2341.2096 0.02 122925 22356 4 2341.207749 586.3097 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 4.75 3620.1 - 1.82E+06 - - - -0.7987 - 4.178 0.599 - 556.7 1 2 0 -0.0019 21 0 0 0 2.15E+06 1.21E+08 - - - 4.9119 1 221125_WJC_METTL3_EV_vs_WT_F08.22363.22363.3 8.03E-09 24/80 R.K[136.11]HAASDVDLEIESLLNQQSTK[136.11].E "sp|Q86U44|MTA70_HUMAN,tr|F5H6D8|F5H6D8_HUMAN,tr|H0YFV6|H0YFV6_HUMAN,tr|B4DTN4|B4DTN4_HUMAN" 4 2341.2096 0.02 122927 22363 3 2341.207352 781.4105 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 4.75 3621.1 - 1.14E+06 - - - -0.9683 - 4.196 0.57 - 910.6 1 2 0 -0.0023 21 0 0 0 2.11E+06 9.95E+07 - - - 8.3326 0.9999 221125_WJC_METTL3_EV_vs_WT_F08.22366.22366.3 1.75E-11 12/100 K.VEEQEPELTSTPNFVVEVIKNDDGKK.A "sp|Q07021|C1QBP_HUMAN,tr|I3L3B0|I3L3B0_HUMAN,tr|I3L3Q7|I3L3Q7_HUMAN" 3 2943.4713 2.22 122929 22366 3 2943.478232 982.1644 "Complement component 1 Q subcomponent-binding protein, mitochondrial OS=Homo sapiens OX=9606 GN=C1QBP PE=1 SV=1" 4.25 3621.4 - 400586 - - - 2.3506 - 2.782 0.627 - 80.8 1 2 1 0.0069 26 0 0 0 6.34E+06 2.86E+06 - - - 7.8825 0.9481 221125_WJC_METTL3_EV_vs_WT_F08.22367.22367.3 0.00217 Jul-68 T.LGNQLDGIHLLDPDVVAR[166.11].F sp|Q86U44|MTA70_HUMAN 1 1954.0511 0.05 122930 22367 3 1954.048051 652.3577 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 4.41 3621.5 - 175215 - - - -1.5834 - 1.537 0.397 - 42.7 1 1 0 -0.0031 18 0 0 0 1.09E+05 2.08E+06 - - - 4.0356 1 221125_WJC_METTL3_EV_vs_WT_F08.22387.22387.4 5.07E-08 12/144 K.KHISQISVAEDDDESLLGHLMIVGK.K sp|P49773|HINT1_HUMAN 1 2733.4007 2.29 122937 22387 4 2733.407094 684.3575 Adenosine 5'-monophosphoramidase HINT1 OS=Homo sapiens OX=9606 GN=HINT1 PE=1 SV=2 4.8 3624.4 - 229024 - - - 2.3279 - 2.867 0.582 - 91.7 1 2 0 0.0064 25 0 0 0 6.48E+06 2.83E+06 - - - 4.625 1 221125_WJC_METTL3_EV_vs_WT_F08.22388.22388.4 9.68E-07 17/162 R.QVASHVGLHSASIPGILALDLC[160.03]PSDTNK.L "sp|Q9UMS4|PRP19_HUMAN,tr|F5GY56|F5GY56_HUMAN" 2 2899.4862 1.73 122938 22388 4 2899.486639 725.8788 Pre-mRNA-processing factor 19 OS=Homo sapiens OX=9606 GN=PRPF19 PE=1 SV=1 5.98 3624.6 - 596267 - - - 0.1542 - 2.894 0.472 - 124 1 2 0 0.0004 28 0 0 0 2.12E+07 1.23E+07 - - - 3.6641 1 221125_WJC_METTL3_EV_vs_WT_F08.22392.22392.3 4.37E-06 Sep-52 K.SNSFFEGVDWEHIR.E sp|Q15208|STK38_HUMAN 1 1721.7798 16.85 122939 22392 3 1721.780915 574.9339 Serine\threonine-protein kinase 38 OS=Homo sapiens OX=9606 GN=STK38 PE=1 SV=1 4.65 3625.2 - 215932 - - - 0.6569 - 2.13 0.546 - 102.1 1 2 0 0.0011 14 0 0 0 4.42E+06 2.63E+05 - - - 6.6365 0.9999 221125_WJC_METTL3_EV_vs_WT_F08.22402.22402.4 0.0145 7/108 R.GLLQDDAHPTLVTYADHSK[136.11].L "sp|Q86U44|MTA70_HUMAN,tr|F5H6D8|F5H6D8_HUMAN,tr|H0YFV6|H0YFV6_HUMAN,tr|B4DTN4|B4DTN4_HUMAN" 4 2088.0367 0.001 122942 22402 4 2088.034139 523.0165 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 5.13 3626.6 - 96022.8 - - - -1.2423 - 1.655 0.456 - 30.8 1 2 0 -0.0026 19 0 0 0 0.00E+00 2.46E+06 - - - 3.3647 0.9951 221125_WJC_METTL3_EV_vs_WT_F08.22408.22408.4 0.00495 7/126 K.LKNFGQELAQVQHSIGQLC[160.03]NTK.D "sp|Q15643|TRIPB_HUMAN,tr|H0YJ97|H0YJ97_HUMAN" 2 2512.2856 1.13 122945 22408 4 2512.291204 629.0787 Thyroid receptor-interacting protein 11 OS=Homo sapiens OX=9606 GN=TRIP11 PE=1 SV=3 8.21 3627.4 - 231856 - - - 2.2139 - 1.861 0.321 - 31.8 1 2 1 0.0056 22 0 0 0 1.65E+07 1.47E+07 - - - 2.2217 0.9997 221125_WJC_METTL3_EV_vs_WT_F08.22414.22414.4 5.83E-07 13/126 K.LK[136.11]NFGQELAQVQHSIGQLC[160.03]NTK[136.11].D "sp|Q15643|TRIPB_HUMAN,tr|H0YJ97|H0YJ97_HUMAN" 2 2528.314 1.13 122948 22414 4 2528.318899 633.0858 Thyroid receptor-interacting protein 11 OS=Homo sapiens OX=9606 GN=TRIP11 PE=1 SV=3 8.21 3628.4 - 367746 - - - 1.921 - 3.004 0.473 - 163.1 1 2 1 0.0049 22 0 0 0 1.67E+07 1.47E+07 - - - 3.7016 0.9999 221125_WJC_METTL3_EV_vs_WT_F08.22421.22421.2 6.51E-05 28-Sep K.GFGFVTFENSADADR.A "sp|O43251|RFOX2_HUMAN,sp|Q9NWB1|RFOX1_HUMAN,tr|A0A6Q8PGE0|A0A6Q8PGE0_HUMAN,tr|A0A6Q8PH77|A0A6Q8PH77_HUMAN,tr|A0A286YEU2|A0A286YEU2_HUMAN,tr|A0A087X2B1|A0A087X2B1_HUMAN,tr|F8VR27|F8VR27_HUMAN,tr|B7Z1U7|B7Z1U7_HUMAN,tr|B0QYV1|B0QYV1_HUMAN,tr|A0A6Q8PHA3|A0A6Q8PHA3_HUMAN,tr|F8VZY7|F8VZY7_HUMAN,tr|B0QYY4|B0QYY4_HUMAN,tr|J3KNW3|J3KNW3_HUMAN,tr|F8VZG9|F8VZG9_HUMAN,tr|F8VRS4|F8VRS4_HUMAN,tr|A0A6Q8PFM4|A0A6Q8PFM4_HUMAN,tr|S4R469|S4R469_HUMAN,tr|A0A804HKG7|A0A804HKG7_HUMAN,tr|A0A0G2JRD1|A0A0G2JRD1_HUMAN,tr|A0A0G2JRA5|A0A0G2JRA5_HUMAN,tr|A0A804HJM2|A0A804HJM2_HUMAN,tr|I3L1D4|I3L1D4_HUMAN,tr|B0QYY7|B0QYY7_HUMAN,tr|A0A0G2JSB3|A0A0G2JSB3_HUMAN,tr|S4R3K7|S4R3K7_HUMAN" 25 1631.7216 1.51 122953 22421 2 1631.720826 816.8681 RNA binding protein fox-1 homolog 2 OS=Homo sapiens OX=9606 GN=RBFOX2 PE=1 SV=3 4.03 3629.2 - 82188.3 - - - -0.4743 - 2.328 0.584 - 216.1 1 2 0 -0.0008 15 0 0 0 3.64E+06 2.40E+06 - - - 5.4317 0.9994 221125_WJC_METTL3_EV_vs_WT_F08.22426.22426.3 0.000275 Oct-84 K.LK[136.11]NFGQELAQVQHSIGQLC[160.03]NTK[136.11].D "sp|Q15643|TRIPB_HUMAN,tr|H0YJ97|H0YJ97_HUMAN" 2 2528.314 1.76 122955 22426 3 2528.313442 843.7786 Thyroid receptor-interacting protein 11 OS=Homo sapiens OX=9606 GN=TRIP11 PE=1 SV=3 8.21 3629.8 - 169224 - - - -0.2373 - 1.721 0.454 - 76.5 1 2 1 -0.0006 22 0 0 0 5.21E+06 2.97E+06 - - - 4.8886 0.9999 221125_WJC_METTL3_EV_vs_WT_F08.22431.22431.4 2.89E-07 17/216 K.QDTVSEPVTPASLAALQSDVQPVGHDYVEEVRNDEGK.V sp|Q96KR1|ZFR_HUMAN 1 3978.9083 2.31 122958 22431 4 3978.908141 995.7344 Zinc finger RNA-binding protein OS=Homo sapiens OX=9606 GN=ZFR PE=1 SV=2 4.07 3630.4 - 363444 - - - -0.0397 - 3.377 0.548 - 86.9 1 2 1 -0.0002 37 0 0 0 1.12E+07 4.83E+06 - - - 4.3525 0.9998 221125_WJC_METTL3_EV_vs_WT_F08.22437.22437.3 5.44E-08 Nov-84 K.LKNFGQELAQVQHSIGQLC[160.03]NTK.D "sp|Q15643|TRIPB_HUMAN,tr|H0YJ97|H0YJ97_HUMAN" 2 2512.2856 1.76 122960 22437 3 2512.289331 838.4358 Thyroid receptor-interacting protein 11 OS=Homo sapiens OX=9606 GN=TRIP11 PE=1 SV=3 8.21 3631.2 - 212615 - - - 1.4684 - 2.405 0.54 - 143 1 2 1 0.0037 22 0 0 0 5.21E+06 2.97E+06 - - - 6.64 0.9887 221125_WJC_METTL3_EV_vs_WT_F08.22445.22445.2 7.77E-05 28-Aug K.GFGFVTFENSADADR[166.11].A "sp|O43251|RFOX2_HUMAN,sp|Q9NWB1|RFOX1_HUMAN,tr|A0A6Q8PGE0|A0A6Q8PGE0_HUMAN,tr|A0A6Q8PH77|A0A6Q8PH77_HUMAN,tr|A0A286YEU2|A0A286YEU2_HUMAN,tr|A0A087X2B1|A0A087X2B1_HUMAN,tr|F8VR27|F8VR27_HUMAN,tr|B7Z1U7|B7Z1U7_HUMAN,tr|B0QYV1|B0QYV1_HUMAN,tr|A0A6Q8PHA3|A0A6Q8PHA3_HUMAN,tr|F8VZY7|F8VZY7_HUMAN,tr|B0QYY4|B0QYY4_HUMAN,tr|J3KNW3|J3KNW3_HUMAN,tr|F8VZG9|F8VZG9_HUMAN,tr|F8VRS4|F8VRS4_HUMAN,tr|A0A6Q8PFM4|A0A6Q8PFM4_HUMAN,tr|S4R469|S4R469_HUMAN,tr|A0A804HKG7|A0A804HKG7_HUMAN,tr|A0A0G2JRD1|A0A0G2JRD1_HUMAN,tr|A0A0G2JRA5|A0A0G2JRA5_HUMAN,tr|A0A804HJM2|A0A804HJM2_HUMAN,tr|I3L1D4|I3L1D4_HUMAN,tr|B0QYY7|B0QYY7_HUMAN,tr|A0A0G2JSB3|A0A0G2JSB3_HUMAN,tr|S4R3K7|S4R3K7_HUMAN" 25 1641.7299 1.51 122964 22445 2 1642.729838 821.8722 RNA binding protein fox-1 homolog 2 OS=Homo sapiens OX=9606 GN=RBFOX2 PE=1 SV=3 4.03 3632.4 - 153440 - - - 609.0941 - 2.043 0.587 - 164.6 1 2 0 1 15 0 0 0 3.64E+06 2.40E+06 - - - 4.819 0.9999 221125_WJC_METTL3_EV_vs_WT_F08.22460.22460.3 2.13E-07 16/92 R.VETGVLK[136.11]PGMVVTFAPVNVTTEVK[136.11].S "sp|P68104|EF1A1_HUMAN,sp|Q5VTE0|EF1A3_HUMAN,tr|A0A7I2V659|A0A7I2V659_HUMAN,tr|A0A7I2V3H3|A0A7I2V3H3_HUMAN,tr|A0A7I2V5N4|A0A7I2V5N4_HUMAN,tr|A0A087WVQ9|A0A087WVQ9_HUMAN" 6 2530.4051 0.22 122970 22460 3 2530.415229 844.4757 Elongation factor 1-alpha 1 OS=Homo sapiens OX=9606 GN=EEF1A1 PE=1 SV=1 6.11 3634.6 - 357146 - - - 3.9839 - 2.754 0.626 - 141.4 1 2 0 0.0101 24 0 0 0 2.41E+06 1.11E+07 - - - 7.8694 0.9986 221125_WJC_METTL3_EV_vs_WT_F08.22481.22481.3 0.0377 Jun-52 K.K[136.11]GPGEVAGTVTGQK[136.11].R "sp|Q86U44|MTA70_HUMAN,tr|F5H6D8|F5H6D8_HUMAN,tr|H0YFV6|H0YFV6_HUMAN,tr|B4DTN4|B4DTN4_HUMAN" 4 1343.738 0.001 122979 22481 3 1343.738073 448.9199 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 8.59 3637.4 - 128496 - - - 0.07 - 1.408 0.326 - 57.4 1 2 0 0.0001 14 0 0 0 0.00E+00 5.33E+06 - - - 3.0839 0.9998 221125_WJC_METTL3_EV_vs_WT_F08.22483.22483.3 8.79E-05 Oct-92 R.VETGVLKPGMVVTFAPVNVTTEVK.S "sp|P68104|EF1A1_HUMAN,sp|Q5VTE0|EF1A3_HUMAN,tr|A0A7I2V659|A0A7I2V659_HUMAN,tr|A0A7I2V3H3|A0A7I2V3H3_HUMAN,tr|A0A7I2V5N4|A0A7I2V5N4_HUMAN,tr|A0A087WVQ9|A0A087WVQ9_HUMAN" 6 2514.3767 0.22 122980 22483 3 2514.377863 839.1329 Elongation factor 1-alpha 1 OS=Homo sapiens OX=9606 GN=EEF1A1 PE=1 SV=1 6.11 3637.6 - 155860 - - - 0.4434 - 2.296 0.368 - 56.5 1 2 0 0.0011 24 0 0 0 2.41E+06 1.11E+07 - - - 4.573 0.9999 221125_WJC_METTL3_EV_vs_WT_F08.22489.22489.3 6.39E-07 13/64 K.ELTTEIDNNIEQISSYK.S "sp|P13645|K1C10_HUMAN,tr|A0A1B0GVI3|A0A1B0GVI3_HUMAN" 2 1995.9637 19.93 122984 22489 3 1995.966585 666.3285 "Keratin, type I cytoskeletal 10 OS=Homo sapiens OX=9606 GN=KRT10 PE=1 SV=6" 4 3638.5 - 294612 - - - 1.4549 - 2.839 0.387 - 182.9 1 2 0 0.0029 17 0 0 0 8.33E+06 4.18E+05 - - - 5.4899 0.9995 221125_WJC_METTL3_EV_vs_WT_F08.22490.22490.4 5.51E-05 12/186 K.SR[166.11]EPQAK[136.11]PQLDLSIDSLDLSC[160.03]EEGTPLSITSK[136.11].L "sp|Q14980|NUMA1_HUMAN,tr|A0A087WY61|A0A087WY61_HUMAN" 2 3539.7875 0.54 122985 22490 4 3539.800254 885.9542 Nuclear mitotic apparatus protein 1 OS=Homo sapiens OX=9606 GN=NUMA1 PE=1 SV=2 4.3 3638.6 - 210777 - - - 3.5948 - 2.753 0.536 - 57.7 1 2 1 0.0127 32 0 0 0 3.11E+06 5.74E+06 - - - 4.1936 1 221125_WJC_METTL3_EV_vs_WT_F08.22498.22498.4 7.31E-08 20/132 R.C[160.03]K[136.11]DDEFTHLYTLIVR[166.11]PDNTYEVK[136.11].L "sp|P27797|CALR_HUMAN,tr|A0A7P0T861|A0A7P0T861_HUMAN,tr|K7EL50|K7EL50_HUMAN,tr|K7EJB9|K7EJB9_HUMAN" 4 2881.4167 1.48 122988 22498 4 2881.430882 721.3614 Calreticulin OS=Homo sapiens OX=9606 GN=CALR PE=1 SV=1 4.83 3639.6 - 483203 - - - 4.9337 - 3.541 0.639 - 258.8 1 2 1 0.0142 23 0 0 0 1.57E+07 1.06E+07 - - - 5.1936 1 221125_WJC_METTL3_EV_vs_WT_F08.22501.22501.4 7.49E-11 30/258 K.ALANVNIGSLIC[160.03]NVGAGGPAPAAGAAPAGGPAPSTAAAPAEEKK.V sp|P05386|RLA1_HUMAN 1 3936.0163 1.51 122989 22501 4 3936.024782 985.0114 60S acidic ribosomal protein P1 OS=Homo sapiens OX=9606 GN=RPLP1 PE=1 SV=1 6.18 3640 - 461504 - - - 2.1423 - 5.755 0.662 - 294.5 1 2 0 0.0084 44 0 0 0 1.01E+07 6.70E+06 - - - 5.4816 1 221125_WJC_METTL3_EV_vs_WT_F08.22508.22508.3 6.06E-07 17/76 K.RIQEIIEQLDVTTSEYEKEK.L "sp|P10809|CH60_HUMAN,tr|A0A7I2V2X6|A0A7I2V2X6_HUMAN,tr|A0A7I2YQK6|A0A7I2YQK6_HUMAN,tr|A0A7I2V599|A0A7I2V599_HUMAN" 4 2450.2541 1.53 122993 22508 3 2450.253092 817.7586 "60 kDa heat shock protein, mitochondrial OS=Homo sapiens OX=9606 GN=HSPD1 PE=1 SV=2" 4.42 3641 - 148310 - - - -0.391 - 3.467 0.588 - 374.6 1 2 1 -0.001 20 0 0 0 1.83E+07 1.20E+07 - - - 8.1116 1 221125_WJC_METTL3_EV_vs_WT_F08.22529.22529.3 5.97E-10 23/76 K.R[166.11]IQEIIEQLDVTTSEYEK[136.11]EK[136.11].L "sp|P10809|CH60_HUMAN,tr|A0A7I2V2X6|A0A7I2V2X6_HUMAN,tr|A0A7I2YQK6|A0A7I2YQK6_HUMAN,tr|A0A7I2V599|A0A7I2V599_HUMAN" 4 2476.2907 1.53 123006 22529 3 2476.292895 826.4375 "60 kDa heat shock protein, mitochondrial OS=Homo sapiens OX=9606 GN=HSPD1 PE=1 SV=2" 4.42 3643.8 - 334921 - - - 0.8783 - 4.063 0.605 - 806.1 1 2 1 0.0022 20 0 0 0 1.83E+07 1.20E+07 - - - 8.6856 1 221125_WJC_METTL3_EV_vs_WT_F08.22531.22531.4 1.78E-07 20/114 K.RIQEIIEQLDVTTSEYEKEK.L "sp|P10809|CH60_HUMAN,tr|A0A7I2V2X6|A0A7I2V2X6_HUMAN,tr|A0A7I2YQK6|A0A7I2YQK6_HUMAN,tr|A0A7I2V599|A0A7I2V599_HUMAN" 4 2450.2541 1.07 123008 22531 4 2450.259118 613.5708 "60 kDa heat shock protein, mitochondrial OS=Homo sapiens OX=9606 GN=HSPD1 PE=1 SV=2" 4.42 3644.1 - 301691 - - - 2.0684 - 3.586 0.619 - 276.3 1 2 1 0.0051 20 0 0 0 9.45E+06 8.87E+06 - - - 5.0393 0.9994 221125_WJC_METTL3_EV_vs_WT_F08.22532.22532.3 4.55E-06 Aug-64 K.AAIDWFDGK[136.11]EFSGNPIK[136.11].V "sp|P35637|FUS_HUMAN,tr|H3BPE7|H3BPE7_HUMAN" 2 1909.9545 1.36 123009 22532 3 1909.960268 637.6588 RNA-binding protein FUS OS=Homo sapiens OX=9606 GN=FUS PE=1 SV=1 4.56 3644.2 - 165905 - - - 3.0126 - 2.359 0.515 - 88.7 1 2 1 0.0058 17 0 0 0 6.50E+06 4.77E+06 - - - 6.4483 0.982 221125_WJC_METTL3_EV_vs_WT_F08.22546.22546.4 3.12E-06 15/162 A.EEEDK[136.11]K[136.11]EDVGTVVGIDLGTTYSC[160.03]VGVFK[136.11].N "sp|P11021|BIP_HUMAN,tr|A0A7P0TB36|A0A7P0TB36_HUMAN,tr|A0A7P0TAI0|A0A7P0TAI0_HUMAN" 3 3097.5228 0.05 123016 22546 4 3097.527497 775.388 Endoplasmic reticulum chaperone BiP OS=Homo sapiens OX=9606 GN=HSPA5 PE=1 SV=2 4.2 3646 - 394003 - - - 1.5283 - 3.215 0.504 - 104.3 1 1 1 0.0047 28 0 0 0 4.58E+05 9.83E+06 - - - 3.9741 1 221125_WJC_METTL3_EV_vs_WT_F08.22551.22551.4 1.67E-12 24/120 S.LHTDGDK[136.11]AFVDFLSDEIK[136.11]EER[166.11].K sp|Q07021|C1QBP_HUMAN 1 2489.2285 1.17 123017 22551 4 2489.231035 623.3144 "Complement component 1 Q subcomponent-binding protein, mitochondrial OS=Homo sapiens OX=9606 GN=C1QBP PE=1 SV=1" 4.38 3646.8 - 358592 - - - 1.0369 - 4.319 0.647 - 411.4 1 1 2 0.0026 21 0 0 0 5.66E+07 4.82E+07 - - - 5.3405 0.9999 221125_WJC_METTL3_EV_vs_WT_F08.22560.22560.4 0.000802 10/126 R.K[136.11]LQEDGLLSNVSHVIVDEVHER[166.11].S "sp|Q7Z478|DHX29_HUMAN,tr|A0A087WYN9|A0A087WYN9_HUMAN" 2 2533.3255 0.38 123023 22560 4 2533.329564 634.3387 ATP-dependent RNA helicase DHX29 OS=Homo sapiens OX=9606 GN=DHX29 PE=1 SV=2 4.87 3647.9 - 105329 - - - 1.59 - 2.438 0.464 - 72.4 1 2 0 0.004 22 0 0 0 1.97E+06 5.15E+06 - - - 3.5551 0.9998 221125_WJC_METTL3_EV_vs_WT_F08.22568.22568.3 4.37E-05 9/128 R.SDSPVPTAPTSGGPK[136.11]PSTASAVPELATDPELEK[136.11].K "sp|Q86U44|MTA70_HUMAN,tr|B4E349|B4E349_HUMAN,tr|F5H6D8|F5H6D8_HUMAN,tr|B4DTN4|B4DTN4_HUMAN" 4 3248.6271 0.01 123027 22568 3 3248.63457 1083.883 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 4.18 3649 - 217681 - - - 2.3 - 1.872 0.485 - 35.5 1 2 0 0.0075 33 0 0 0 5.99E+04 7.15E+06 - - - 5.3877 1 221125_WJC_METTL3_EV_vs_WT_F08.22570.22570.3 4.12E-13 22/80 S.LHTDGDK[136.11]AFVDFLSDEIK[136.11]EER[166.11].K sp|Q07021|C1QBP_HUMAN 1 2489.2285 1.26 123028 22570 3 2489.234183 830.7501 "Complement component 1 Q subcomponent-binding protein, mitochondrial OS=Homo sapiens OX=9606 GN=C1QBP PE=1 SV=1" 4.38 3649.3 - 227132 - - - 2.3015 - 4.261 0.742 - 407.9 1 1 2 0.0057 21 0 0 0 8.54E+06 6.80E+06 - - - 10.2861 0.9879 221125_WJC_METTL3_EV_vs_WT_F08.22574.22574.3 3.71E-06 9/124 R.KINSSPNVNTTASGVEDLNIIQVTIPDDDNER.L "sp|P78347|GTF2I_HUMAN,tr|A0A494C1K3|A0A494C1K3_HUMAN" 2 3467.7016 2.12 123030 22574 3 3468.689901 1156.9078 General transcription factor II-I OS=Homo sapiens OX=9606 GN=GTF2I PE=1 SV=2 3.96 3649.7 - 340390 - - - 285.0017 - 2.17 0.542 - 39.6 1 2 0 0.9883 32 0 0 0 2.64E+07 1.25E+07 - - - 6.0914 1 221125_WJC_METTL3_EV_vs_WT_F08.22577.22577.3 3.91E-09 15/100 R.YAQPATATAATAAAAAAAAYSDGYGR.V "sp|O43251|RFOX2_HUMAN,tr|B0QYV1|B0QYV1_HUMAN,tr|A0A0G2JRD1|A0A0G2JRD1_HUMAN,tr|A0A0G2JRA5|A0A0G2JRA5_HUMAN,tr|S4R3K7|S4R3K7_HUMAN" 5 2431.1404 2.36 123032 22577 3 2431.142432 811.3874 RNA binding protein fox-1 homolog 2 OS=Homo sapiens OX=9606 GN=RBFOX2 PE=1 SV=3 5.83 3650.1 - 177882 - - - 0.8288 - 3.345 0.674 - 261.2 1 2 0 0.002 26 0 0 0 3.26E+06 1.38E+06 - - - 8.8318 0.9284 221125_WJC_METTL3_EV_vs_WT_F08.22586.22586.3 5.14E-05 9/124 R.K[136.11]INSSPNVNTTASGVEDLNIIQVTIPDDDNER[166.11].L "sp|P78347|GTF2I_HUMAN,tr|A0A494C1K3|A0A494C1K3_HUMAN" 2 3485.7241 3.11 123037 22586 3 3486.703955 1162.9153 General transcription factor II-I OS=Homo sapiens OX=9606 GN=GTF2I PE=1 SV=2 3.96 3651.2 - 228107 - - - 281.1138 - 2.13 0.529 - 40.1 1 2 0 0.9799 32 0 0 0 2.97E+06 9.54E+05 - - - 5.906 1 221125_WJC_METTL3_EV_vs_WT_F08.22587.22587.3 1.43E-11 13/116 K.APKPEDIDEEDDDVPDLVENFDEASKNEAN.- sp|Q96K17|BT3L4_HUMAN 1 3358.4485 0.89 123038 22587 3 3358.448586 1120.4901 Transcription factor BTF3 homolog 4 OS=Homo sapiens OX=9606 GN=BTF3L4 PE=1 SV=1 3.58 3651.4 - 173320 - - - 0.036 - 3.407 0.775 - 100.7 1 2 1 0.0001 30 0 0 0 1.95E+07 2.18E+07 - - - 10.0006 1 221125_WJC_METTL3_EV_vs_WT_F08.22597.22597.3 3.61E-12 26/104 K.KYQDEYGVSSIIPNFQISQDSVGNSNR.S sp|Q8WVD3|RN138_HUMAN 1 3044.4476 0.94 123043 22597 3 3044.450488 1015.8231 E3 ubiquitin-protein ligase RNF138 OS=Homo sapiens OX=9606 GN=RNF138 PE=1 SV=1 4.56 3652.7 - 531490 - - - 0.9624 - 4.38 0.694 - 793.8 1 2 0 0.0029 27 0 0 0 2.68E+07 2.85E+07 - - - 9.6748 1 221125_WJC_METTL3_EV_vs_WT_F08.22599.22599.4 1.10E-08 29/120 R.K[136.11]HAASDVDLEIESLLNQQSTK[136.11].E "sp|Q86U44|MTA70_HUMAN,tr|F5H6D8|F5H6D8_HUMAN,tr|H0YFV6|H0YFV6_HUMAN,tr|B4DTN4|B4DTN4_HUMAN" 4 2341.2096 0.02 123044 22599 4 2341.209962 586.3097 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 4.75 3652.9 - 1.10E+06 - - - 0.1465 - 4.787 0.573 - 781 1 2 0 0.0003 21 0 0 0 1.00E+06 4.79E+07 - - - 4.731 1 221125_WJC_METTL3_EV_vs_WT_F08.22600.22600.3 1.50E-09 24/80 R.K[136.11]HAASDVDLEIESLLNQQSTK[136.11].E "sp|Q86U44|MTA70_HUMAN,tr|F5H6D8|F5H6D8_HUMAN,tr|H0YFV6|H0YFV6_HUMAN,tr|B4DTN4|B4DTN4_HUMAN" 4 2341.2096 0 123045 22600 3 2341.207912 781.4105 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 4.75 3653 - 1.01E+06 - - - -0.7291 - 4.473 0.617 - 990.2 1 2 0 -0.0017 21 0 0 0 3.96E+04 3.41E+07 - - - 9.01 0.9718 221125_WJC_METTL3_EV_vs_WT_F08.22602.22602.4 9.76E-06 9/186 R.KINSSPNVNTTASGVEDLNIIQVTIPDDDNER.L "sp|P78347|GTF2I_HUMAN,tr|A0A494C1K3|A0A494C1K3_HUMAN" 2 3467.7016 0.78 123047 22602 4 3468.688077 867.9327 General transcription factor II-I OS=Homo sapiens OX=9606 GN=GTF2I PE=1 SV=2 3.96 3653.3 - 319614 - - - 284.4757 - 2.341 0.477 - 22.6 1 2 0 0.9865 32 0 0 0 1.68E+06 2.15E+06 - - - 3.3614 1 221125_WJC_METTL3_EV_vs_WT_F08.22618.22618.3 1.18E-09 14/116 K.APK[136.11]PEDIDEEDDDVPDLVENFDEASK[136.11]NEAN.- sp|Q96K17|BT3L4_HUMAN 1 3374.4769 0.89 123057 22618 3 3374.480466 1125.8329 Transcription factor BTF3 homolog 4 OS=Homo sapiens OX=9606 GN=BTF3L4 PE=1 SV=1 3.58 3655.4 - 332762 - - - 1.0671 - 3.387 0.672 - 136.1 1 2 1 0.0036 30 0 0 0 1.95E+07 2.18E+07 - - - 8.8378 1 221125_WJC_METTL3_EV_vs_WT_F08.22623.22623.4 8.21E-05 11/138 K.NELHNLLDK[136.11]PQLQGIPVLVLGNK[136.11]R[166.11].D "sp|Q96BM9|ARL8A_HUMAN,sp|Q9NVJ2|ARL8B_HUMAN" 2 2733.5864 1.32 123060 22623 4 2733.593837 684.4039 ADP-ribosylation factor-like protein 8A OS=Homo sapiens OX=9606 GN=ARL8A PE=1 SV=1 8.6 3656.1 - 124466 - - - 2.7246 - 2.57 0.588 - 76.3 1 2 0 0.0074 24 0 0 0 8.74E+06 6.61E+06 - - - 4.6449 1 221125_WJC_METTL3_EV_vs_WT_F08.22624.22624.4 1.46E-14 16/156 K.KYQDEYGVSSIIPNFQISQDSVGNSNR.S sp|Q8WVD3|RN138_HUMAN 1 3044.4476 0.61 123061 22624 4 3044.454744 762.1192 E3 ubiquitin-protein ligase RNF138 OS=Homo sapiens OX=9606 GN=RNF138 PE=1 SV=1 4.56 3656.2 - 246876 - - - 2.3604 - 3.735 0.677 - 127.3 1 2 0 0.0072 27 0 0 0 6.81E+06 1.12E+07 - - - 5.5289 0.9999 221125_WJC_METTL3_EV_vs_WT_F08.22628.22628.2 0.00379 26-Nov K.LISWYDNEFGYSNR[166.11].V "sp|P04406|G3P_HUMAN,tr|E7EUT5|E7EUT5_HUMAN" 2 1772.8034 1.03 123063 22628 2 1772.805555 887.409 Glyceraldehyde-3-phosphate dehydrogenase OS=Homo sapiens OX=9606 GN=GAPDH PE=1 SV=3 4.37 3656.8 - 153893 - - - 1.2325 - 2.466 0.582 - 461.2 1 2 0 0.0022 14 0 0 0 1.38E+07 1.34E+07 - - - 5.604 1 221125_WJC_METTL3_EV_vs_WT_F08.22633.22633.2 9.56E-10 26-Dec K.LISWYDNEFGYSNR.V "sp|P04406|G3P_HUMAN,tr|E7EUT5|E7EUT5_HUMAN" 2 1762.7951 1.02 123065 22633 2 1762.795282 882.4048 Glyceraldehyde-3-phosphate dehydrogenase OS=Homo sapiens OX=9606 GN=GAPDH PE=1 SV=3 4.37 3657.5 - 213814 - - - 0.1032 - 2.62 0.73 - 503.5 1 2 0 0.0002 14 0 0 0 1.38E+07 1.35E+07 - - - 6.8498 0.9992 221125_WJC_METTL3_EV_vs_WT_F08.22638.22638.2 0.0158 22-Aug K.DAGVIAGLNVLR[166.11].L "sp|P0DMV8|HS71A_HUMAN,sp|P34931|HS71L_HUMAN,sp|P0DMV9|HS71B_HUMAN,tr|Q53FA3|Q53FA3_HUMAN,tr|A0A0G2JIW1|A0A0G2JIW1_HUMAN" 5 1206.696 0.13 123068 22638 2 1206.698177 604.3553 Heat shock 70 kDa protein 1A OS=Homo sapiens OX=9606 GN=HSPA1A PE=1 SV=1 5.84 3658.2 - 157796 - - - 1.8116 - 1.711 0.383 - 244.6 1 2 0 0.0022 12 0 0 0 2.13E+06 1.63E+07 - - - 3.2823 1 221125_WJC_METTL3_EV_vs_WT_F08.22639.22639.4 4.30E-11 18/120 S.LHTDGDKAFVDFLSDEIKEER.K sp|Q07021|C1QBP_HUMAN 1 2463.1918 1.17 123069 22639 4 2463.196578 616.8052 "Complement component 1 Q subcomponent-binding protein, mitochondrial OS=Homo sapiens OX=9606 GN=C1QBP PE=1 SV=1" 4.38 3658.3 - 500800 - - - 1.9463 - 4.075 0.628 - 247 1 1 2 0.0048 21 0 0 0 5.66E+07 4.82E+07 - - - 5.1553 1 221125_WJC_METTL3_EV_vs_WT_F08.22640.22640.4 0.00194 19/138 K.NELHNLLDKPQLQGIPVLVLGNKR.D "sp|Q96BM9|ARL8A_HUMAN,sp|Q9NVJ2|ARL8B_HUMAN" 2 2707.5497 1.32 123070 22640 4 2707.557536 677.8947 ADP-ribosylation factor-like protein 8A OS=Homo sapiens OX=9606 GN=ARL8A PE=1 SV=1 8.6 3658.5 - 333644 - - - 2.8871 - 3.71 0.625 - 269.2 1 2 0 0.0078 24 0 0 0 8.74E+06 6.61E+06 - - - 5.0846 0.9591 221125_WJC_METTL3_EV_vs_WT_F08.22645.22645.3 0.372 Jun-52 K.LISWYDNEFGYSNR[166.11].V "sp|P04406|G3P_HUMAN,tr|E7EUT5|E7EUT5_HUMAN" 2 1772.8034 1.15 123073 22645 3 1772.807586 591.9417 Glyceraldehyde-3-phosphate dehydrogenase OS=Homo sapiens OX=9606 GN=GAPDH PE=1 SV=3 4.37 3659.1 - 164528 - - - 2.3782 - 1.097 0.243 - 50.4 1 2 0 0.0042 14 0 0 0 4.71E+06 4.08E+06 - - - 1.4941 0.9999 221125_WJC_METTL3_EV_vs_WT_F08.22657.22657.4 0.0068 8/108 R.GLLQDDAHPTLVTYADHSK[136.11].L "sp|Q86U44|MTA70_HUMAN,tr|F5H6D8|F5H6D8_HUMAN,tr|H0YFV6|H0YFV6_HUMAN,tr|B4DTN4|B4DTN4_HUMAN" 4 2088.0367 0.001 123079 22657 4 2088.04086 523.0165 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 5.13 3660.7 - 78239.6 - - - 1.9765 - 1.456 0.45 - 33.4 1 2 0 0.0041 19 0 0 0 0.00E+00 4.14E+06 - - - 3.2687 1 221125_WJC_METTL3_EV_vs_WT_F08.22678.22678.4 3.21E-08 15/168 K.TAVIDHHNYDISDLGQHTLIVADTENLLK.A "sp|P39656|OST48_HUMAN,tr|U3KQ84|U3KQ84_HUMAN,tr|A0A0C4DGS1|A0A0C4DGS1_HUMAN" 3 3244.6364 1.12 123089 22678 4 3244.63968 812.1664 Dolichyl-diphosphooligosaccharide--protein glycosyltransferase 48 kDa subunit OS=Homo sapiens OX=9606 GN=DDOST PE=1 SV=4 4.7 3663.6 - 239384 - - - 1.0044 - 2.913 0.564 - 84.6 1 2 0 0.0033 29 0 0 0 6.33E+06 5.64E+06 - - - 4.4637 1 221125_WJC_METTL3_EV_vs_WT_F08.22686.22686.3 9.46E-06 10/112 R.R[166.11]AEQDSTTVAAFASSLVSGLNSSASEPAK[136.11].E "sp|Q86U44|MTA70_HUMAN,tr|F5H6D8|F5H6D8_HUMAN,tr|H0YFV6|H0YFV6_HUMAN,tr|B4DTN4|B4DTN4_HUMAN" 4 2898.4326 0.001 123092 22686 3 2898.431841 967.1515 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 4.68 3664.7 - 117374 - - - -0.255 - 2.857 0.551 - 57.2 1 2 0 -0.0007 29 0 0 0 0.00E+00 3.89E+06 - - - 7.098 1 221125_WJC_METTL3_EV_vs_WT_F08.22703.22703.4 6.85E-10 17/228 W.GVYPASLFQQQAAAAAAATNSANQQTTPQAQQGQQQVLR.G "sp|Q14671|PUM1_HUMAN,tr|Q5T1Z8|Q5T1Z8_HUMAN,tr|H0YDK8|H0YDK8_HUMAN,tr|H0YEH2|H0YEH2_HUMAN,tr|Q5T1Z4|Q5T1Z4_HUMAN,tr|H0YED4|H0YED4_HUMAN,tr|E9PR38|E9PR38_HUMAN" 7 4041.0053 4.47 123098 22703 4 4041.020314 1011.2586 Pumilio homolog 1 OS=Homo sapiens OX=9606 GN=PUM1 PE=1 SV=3 8.75 3667.4 - 181747 - - - 3.7233 - 3.455 0.652 - 92.8 1 1 0 0.015 39 0 0 0 6.55E+06 1.47E+06 - - - 5.2565 0.9998 221125_WJC_METTL3_EV_vs_WT_F08.22714.22714.4 7.97E-07 15/174 K.EQELNQSISEKETLIAEIEELDRQNQEATK.H "sp|Q15643|TRIPB_HUMAN,tr|H0YJ97|H0YJ97_HUMAN" 2 3514.7275 1.36 123104 22714 4 3514.735381 879.6891 Thyroid receptor-interacting protein 11 OS=Homo sapiens OX=9606 GN=TRIP11 PE=1 SV=3 4.14 3668.8 - 245118 - - - 2.2477 - 3.584 0.518 - 103.3 1 2 2 0.0079 30 0 0 0 8.46E+06 6.21E+06 - - - 4.1231 0.9942 221125_WJC_METTL3_EV_vs_WT_F08.22720.22720.4 0.0412 6/132 K.VHSHSAEMEAQLSQALEELGGQK.Q "sp|Q9Y6D9|MD1L1_HUMAN,tr|C9JX80|C9JX80_HUMAN" 2 2478.1809 1.83 123107 22720 4 2478.189562 620.5525 Mitotic spindle assembly checkpoint protein MAD1 OS=Homo sapiens OX=9606 GN=MAD1L1 PE=1 SV=2 4.87 3669.7 - 92770.6 - - - 3.4949 - 1.547 0.296 - 27.5 1 2 0 0.0087 23 0 0 0 5.16E+07 2.81E+07 - - - 1.9413 0.9999 221125_WJC_METTL3_EV_vs_WT_F08.22726.22726.3 4.08E-06 Sep-52 K.K[136.11]GPGEVAGTVTGQK[136.11].R "sp|Q86U44|MTA70_HUMAN,tr|F5H6D8|F5H6D8_HUMAN,tr|H0YFV6|H0YFV6_HUMAN,tr|B4DTN4|B4DTN4_HUMAN" 4 1343.738 0.001 123110 22726 3 1343.740582 448.9199 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 8.59 3670.5 - 61760.4 - - - 1.9371 - 1.838 0.528 - 102.9 1 2 0 0.0026 14 0 0 0 0.00E+00 6.84E+06 - - - 6.0435 0.9868 221125_WJC_METTL3_EV_vs_WT_F08.22729.22729.4 0.0312 6/138 K.SNIPQSEVSHKEDQIQEILEGLQK.L "sp|O60281|ZN292_HUMAN,tr|J3KNV1|J3KNV1_HUMAN" 2 2748.393 1.5 123113 22729 4 2748.400894 688.1055 Zinc finger protein 292 OS=Homo sapiens OX=9606 GN=ZNF292 PE=1 SV=3 4.57 3670.9 - 107139 - - - 2.8711 - 1.463 0.303 - 12.3 1 2 1 0.0079 24 0 0 0 1.92E+06 1.28E+06 - - - 1.9833 1 221125_WJC_METTL3_EV_vs_WT_F08.22734.22734.4 3.92E-09 16/252 R.YNSSSISSVLKDPDSNPYSLLDTSEPEPPVDSEPGEPPPASAR.R sp|P51116|FXR2_HUMAN 1 4527.1089 1.37 123116 22734 4 4527.118384 1132.7845 Fragile X mental retardation syndrome-related protein 2 OS=Homo sapiens OX=9606 GN=FXR2 PE=1 SV=2 3.85 3671.5 - 609551 - - - 2.0929 - 2.814 0.662 - 48.4 1 2 1 0.0095 43 0 0 0 5.11E+07 3.74E+07 - - - 5.2799 0.9999 221125_WJC_METTL3_EV_vs_WT_F08.22741.22741.3 1.30E-05 13/68 K.ISSIQSIVPALEIANAHR.K "sp|P10809|CH60_HUMAN,tr|A0A7I2V2X6|A0A7I2V2X6_HUMAN,tr|A0A7I2YQK6|A0A7I2YQK6_HUMAN,tr|A0A7I2V599|A0A7I2V599_HUMAN,tr|A0A7I2YQ71|A0A7I2YQ71_HUMAN,tr|A0A7I2V5M1|A0A7I2V5M1_HUMAN,tr|A0A7I2V5K3|A0A7I2V5K3_HUMAN,tr|A0A7I2V369|A0A7I2V369_HUMAN" 8 1918.0636 1.32 123121 22741 3 1918.067819 640.3618 "60 kDa heat shock protein, mitochondrial OS=Homo sapiens OX=9606 GN=HSPD1 PE=1 SV=2" 6.75 3672.5 - 170546 - - - 2.1944 - 2.513 0.495 - 213.3 1 2 0 0.0042 18 0 0 0 5.93E+07 4.50E+07 - - - 6.3522 0.9999 221125_WJC_METTL3_EV_vs_WT_F08.22743.22743.3 4.29E-07 Dec-68 K.ISSIQSIVPALEIANAHR[166.11].K "sp|P10809|CH60_HUMAN,tr|A0A7I2V2X6|A0A7I2V2X6_HUMAN,tr|A0A7I2YQK6|A0A7I2YQK6_HUMAN,tr|A0A7I2V599|A0A7I2V599_HUMAN,tr|A0A7I2YQ71|A0A7I2YQ71_HUMAN,tr|A0A7I2V5M1|A0A7I2V5M1_HUMAN,tr|A0A7I2V5K3|A0A7I2V5K3_HUMAN,tr|A0A7I2V369|A0A7I2V369_HUMAN" 8 1928.0719 1.32 123123 22743 3 1928.077824 643.6979 "60 kDa heat shock protein, mitochondrial OS=Homo sapiens OX=9606 GN=HSPD1 PE=1 SV=2" 6.75 3672.8 - 102556 - - - 3.0829 - 2.619 0.584 - 162.3 1 2 0 0.0059 18 0 0 0 5.93E+07 4.51E+07 - - - 7.4468 0.9999 221125_WJC_METTL3_EV_vs_WT_F08.22747.22747.4 4.82E-09 20/174 K.EQELNQSISEK[136.11]ETLIAEIEELDR[166.11]QNQEATK[136.11].H "sp|Q15643|TRIPB_HUMAN,tr|H0YJ97|H0YJ97_HUMAN" 2 3540.7642 1.36 123126 22747 4 3540.7675 886.1983 Thyroid receptor-interacting protein 11 OS=Homo sapiens OX=9606 GN=TRIP11 PE=1 SV=3 4.14 3673.4 - 383912 - - - 0.9458 - 3.902 0.57 - 151.7 1 2 2 0.0034 30 0 0 0 8.46E+06 6.21E+06 - - - 4.603 1 221125_WJC_METTL3_EV_vs_WT_F08.22751.22751.4 7.79E-14 27/192 R.SSHYGGSLPNVNQIGSGLAEFQSPLHSPLDSSR.S sp|Q53ET0|CRTC2_HUMAN 1 3437.66 1.43 123129 22751 4 3437.663255 860.4223 CREB-regulated transcription coactivator 2 OS=Homo sapiens OX=9606 GN=CRTC2 PE=1 SV=2 5.94 3673.9 - 293358 - - - 0.944 - 4.777 0.732 - 411.3 1 2 0 0.0032 33 0 0 0 6.71E+07 4.68E+07 - - - 6.0656 0.9991 221125_WJC_METTL3_EV_vs_WT_F08.22752.22752.3 0.00109 Sep-64 R.IQEIIEQLDVTTSEYEK[136.11].E "sp|P10809|CH60_HUMAN,tr|A0A7I2V2X6|A0A7I2V2X6_HUMAN,tr|A0A7I2YQK6|A0A7I2YQK6_HUMAN,tr|A0A7I2V599|A0A7I2V599_HUMAN" 4 2045.0296 1.52 123130 22752 3 2045.03515 682.6838 "60 kDa heat shock protein, mitochondrial OS=Homo sapiens OX=9606 GN=HSPD1 PE=1 SV=2" 3.91 3674 - 86528.7 - - - 2.7227 - 1.792 0.378 - 101.8 1 2 0 0.0056 17 0 0 0 2.95E+06 1.94E+06 - - - 4.2265 1 221125_WJC_METTL3_EV_vs_WT_F08.22757.22757.4 1.96E-16 24/192 R.SSHYGGSLPNVNQIGSGLAEFQSPLHSPLDSSR[166.11].S sp|Q53ET0|CRTC2_HUMAN 1 3447.6683 1.43 123133 22757 4 3447.680101 862.9243 CREB-regulated transcription coactivator 2 OS=Homo sapiens OX=9606 GN=CRTC2 PE=1 SV=2 5.94 3674.7 - 329446 - - - 3.4287 - 4.405 0.696 - 263.6 1 2 0 0.0118 33 0 0 0 6.67E+07 4.65E+07 - - - 5.7256 1 221125_WJC_METTL3_EV_vs_WT_F08.22762.22762.3 7.29E-13 16/88 K.VHSHSAEMEAQLSQALEELGGQK[136.11].Q "sp|Q9Y6D9|MD1L1_HUMAN,tr|C9JX80|C9JX80_HUMAN" 2 2486.1951 1.25 123136 22762 3 2486.195389 829.739 Mitotic spindle assembly checkpoint protein MAD1 OS=Homo sapiens OX=9606 GN=MAD1L1 PE=1 SV=2 4.87 3675.4 - 232851 - - - 0.1158 - 3.629 0.618 - 316.8 1 2 0 0.0003 23 0 0 0 1.52E+07 1.22E+07 - - - 8.4538 0.9536 221125_WJC_METTL3_EV_vs_WT_F08.22768.22768.4 0.0877 6/240 R.DEDLVVAQQINAQRPEPQSDNDSSATC[160.03]SADEDVDGEPERQR[166.11].M "sp|O75376|NCOR1_HUMAN,tr|A0A088AWL3|A0A088AWL3_HUMAN" 2 4580.0105 - 123139 22768 4 4580.02868 1146.0099 Nuclear receptor corepressor 1 OS=Homo sapiens OX=9606 GN=NCOR1 PE=1 SV=2 3.79 3676.3 - 190634 - - - 3.9696 - 0.928 0.297 - 7.9 1 2 1 0.0182 41 0 0 0 - - - - - 1.7846 0.9998 221125_WJC_METTL3_EV_vs_WT_F08.22770.22770.4 1.70E-06 15/252 R.YNSSSISSVLK[136.11]DPDSNPYSLLDTSEPEPPVDSEPGEPPPASAR[166.11].R sp|P51116|FXR2_HUMAN 1 4545.1314 1.36 123140 22770 4 4545.139798 1137.2901 Fragile X mental retardation syndrome-related protein 2 OS=Homo sapiens OX=9606 GN=FXR2 PE=1 SV=2 3.85 3676.5 - 921905 - - - 1.8523 - 2.746 0.532 - 50.2 1 2 1 0.0084 43 0 0 0 5.11E+07 3.75E+07 - - - 4.1417 0.9999 221125_WJC_METTL3_EV_vs_WT_F08.22774.22774.3 2.74E-08 Nov-76 K.FEAHPNDLYVEGLPENIPFR[166.11].S "sp|P78347|GTF2I_HUMAN,tr|A0A494C0Q7|A0A494C0Q7_HUMAN,tr|A0A494C1K3|A0A494C1K3_HUMAN" 3 2366.1571 0.67 123143 22774 3 2366.16273 789.7263 General transcription factor II-I OS=Homo sapiens OX=9606 GN=GTF2I PE=1 SV=2 4.4 3677 - 220875 - - - 2.3933 - 2.593 0.522 - 87.4 1 2 0 0.0057 20 0 0 0 4.27E+06 6.35E+06 - - - 6.6698 1 221125_WJC_METTL3_EV_vs_WT_F08.22779.22779.4 7.50E-15 26/132 K.VHSHSAEMEAQLSQALEELGGQK[136.11].Q "sp|Q9Y6D9|MD1L1_HUMAN,tr|C9JX80|C9JX80_HUMAN" 2 2486.1951 1.8 123145 22779 4 2486.197176 622.5561 Mitotic spindle assembly checkpoint protein MAD1 OS=Homo sapiens OX=9606 GN=MAD1L1 PE=1 SV=2 4.87 3677.6 - 798225 - - - 0.8346 - 4.524 0.67 - 633.6 1 2 0 0.0021 23 0 0 0 5.03E+07 2.80E+07 - - - 5.5461 0.9843 221125_WJC_METTL3_EV_vs_WT_F08.22792.22792.2 0.000491 24-May K.C[160.03]EFQDAYVLLSEK[136.11].K "sp|P10809|CH60_HUMAN,tr|A0A7I2V2X6|A0A7I2V2X6_HUMAN,tr|A0A7I2YQK6|A0A7I2YQK6_HUMAN,tr|A0A7I2V599|A0A7I2V599_HUMAN,tr|A0A7I2YQ71|A0A7I2YQ71_HUMAN,tr|A0A7I2V5M1|A0A7I2V5M1_HUMAN,tr|A0A7I2V5K3|A0A7I2V5K3_HUMAN,tr|A0A7I2V369|A0A7I2V369_HUMAN" 8 1608.7585 1.01 123152 22792 2 1608.766486 805.3865 "60 kDa heat shock protein, mitochondrial OS=Homo sapiens OX=9606 GN=HSPD1 PE=1 SV=2" 4.14 3679.4 - 48475.8 - - - 4.9579 - 1.212 0.407 - 54.3 1 2 0 0.008 13 0 0 0 5.96E+06 5.89E+06 - - - 2.5381 0.9978 221125_WJC_METTL3_EV_vs_WT_F08.22796.22796.2 4.64E-05 24-Jun K.C[160.03]EFQDAYVLLSEK.K "sp|P10809|CH60_HUMAN,tr|A0A7I2V2X6|A0A7I2V2X6_HUMAN,tr|A0A7I2YQK6|A0A7I2YQK6_HUMAN,tr|A0A7I2V599|A0A7I2V599_HUMAN,tr|A0A7I2YQ71|A0A7I2YQ71_HUMAN,tr|A0A7I2V5M1|A0A7I2V5M1_HUMAN,tr|A0A7I2V5K3|A0A7I2V5K3_HUMAN,tr|A0A7I2V369|A0A7I2V369_HUMAN" 8 1600.7443 1.01 123153 22796 2 1600.75031 801.3794 "60 kDa heat shock protein, mitochondrial OS=Homo sapiens OX=9606 GN=HSPD1 PE=1 SV=2" 4.14 3680 - 87337.9 - - - 3.7483 - 1.477 0.494 - 83.5 1 2 0 0.006 13 0 0 0 5.96E+06 5.89E+06 - - - 3.6888 0.9514 221125_WJC_METTL3_EV_vs_WT_F08.22806.22806.3 6.27E-05 Aug-72 L.TLGNQLDGIHLLDPDVVAR[166.11].F sp|Q86U44|MTA70_HUMAN 1 2055.0988 0.01 123158 22806 3 2055.105491 686.0402 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 4.41 3681.1 - 92011.7 - - - 3.2446 - 1.763 0.467 - 45.1 1 1 0 0.0067 19 0 0 0 5.34E+04 5.17E+06 - - - 5.1378 0.8344 221125_WJC_METTL3_EV_vs_WT_F08.22819.22819.4 0.0003 12/168 D.STTVAAFASSLVSGLNSSASEPAK[136.11]EPAK[136.11]K[136.11].S "sp|Q86U44|MTA70_HUMAN,tr|F5H6D8|F5H6D8_HUMAN,tr|H0YFV6|H0YFV6_HUMAN,tr|B4DTN4|B4DTN4_HUMAN" 4 2858.5088 0.19 123162 22819 4 2858.518985 715.6345 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 8.22 3683.1 - 204613 - - - 3.5742 - 2.422 0.434 - 57.5 1 1 1 0.0102 29 0 0 0 6.67E+05 3.55E+06 - - - 3.2733 1 221125_WJC_METTL3_EV_vs_WT_F08.22822.22822.3 4.59E-09 25/80 R.K[136.11]HAASDVDLEIESLLNQQSTK[136.11].E "sp|Q86U44|MTA70_HUMAN,tr|F5H6D8|F5H6D8_HUMAN,tr|H0YFV6|H0YFV6_HUMAN,tr|B4DTN4|B4DTN4_HUMAN" 4 2341.2096 0 123164 22822 3 2341.212737 781.4105 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 4.75 3683.5 - 638722 - - - 1.3318 - 4.767 0.637 - 1053.2 1 2 0 0.0031 21 0 0 0 1.83E+05 4.41E+07 - - - 9.3852 1 221125_WJC_METTL3_EV_vs_WT_F08.22834.22834.3 8.75E-08 13/128 R.SDSPVPTAPTSGGPK[136.11]PSTASAVPELATDPELEK[136.11].K "sp|Q86U44|MTA70_HUMAN,tr|B4E349|B4E349_HUMAN,tr|F5H6D8|F5H6D8_HUMAN,tr|B4DTN4|B4DTN4_HUMAN" 4 3248.6271 0.001 123168 22834 3 3248.629317 1083.883 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 4.18 3685.2 - 163285 - - - 0.6831 - 2.561 0.525 - 73 1 2 0 0.0022 33 0 0 0 0.00E+00 9.22E+06 - - - 6.5561 1 221125_WJC_METTL3_EV_vs_WT_F08.22839.22839.3 1.56E-07 16/108 K.QPNENGVSVQNENFEEIINLPIGSKPSR.L "sp|Q14244|MAP7_HUMAN,tr|A0A087WZ40|A0A087WZ40_HUMAN" 2 3108.5476 1.37 123171 22839 3 3108.555861 1037.1898 Ensconsin OS=Homo sapiens OX=9606 GN=MAP7 PE=1 SV=1 4.49 3685.9 - 202211 - - - 2.6556 - 3.192 0.562 - 130.7 1 2 0 0.0083 28 0 0 0 6.58E+06 4.81E+06 - - - 7.4737 0.9993 221125_WJC_METTL3_EV_vs_WT_F08.22841.22841.4 0.000171 10/162 K.QPNENGVSVQNENFEEIINLPIGSKPSR.L "sp|Q14244|MAP7_HUMAN,tr|A0A087WZ40|A0A087WZ40_HUMAN" 2 3108.5476 1.56 123173 22841 4 3108.561832 778.1442 Ensconsin OS=Homo sapiens OX=9606 GN=MAP7 PE=1 SV=1 4.49 3686.1 - 123975 - - - 4.5764 - 1.959 0.462 - 35.8 1 2 0 0.0142 28 0 0 0 2.99E+06 1.91E+06 - - - 3.4521 1 221125_WJC_METTL3_EV_vs_WT_F08.22851.22851.3 2.55E-08 13/108 K.QPNENGVSVQNENFEEIINLPIGSK[136.11]PSR[166.11].L "sp|Q14244|MAP7_HUMAN,tr|A0A087WZ40|A0A087WZ40_HUMAN" 2 3126.5701 1.37 123179 22851 3 3126.574005 1043.1973 Ensconsin OS=Homo sapiens OX=9606 GN=MAP7 PE=1 SV=1 4.49 3687.5 - 259931 - - - 1.2566 - 2.757 0.653 - 98.8 1 2 0 0.0039 28 0 0 0 6.58E+06 4.81E+06 - - - 8.1524 1 221125_WJC_METTL3_EV_vs_WT_F08.22854.22854.3 1.08E-09 Dec-60 K.K[136.11]VSQEILELLNTTTAK[136.11].E "sp|Q86U44|MTA70_HUMAN,tr|H0YFV6|H0YFV6_HUMAN" 2 1803.0324 0.01 123180 22854 3 1803.032712 602.0181 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 6.14 3688.1 - 276111 - - - 0.1564 - 2.988 0.594 - 266 1 2 0 0.0003 16 0 0 0 2.34E+07 1.91E+09 - - - 7.971 1 221125_WJC_METTL3_EV_vs_WT_F08.22868.22868.2 8.87E-08 13/30 K.K[136.11]VSQEILELLNTTTAK[136.11].E "sp|Q86U44|MTA70_HUMAN,tr|H0YFV6|H0YFV6_HUMAN" 2 1803.0324 0.001 123189 22868 2 1803.034946 902.5235 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 6.14 3689.9 - 122620 - - - 1.3954 - 2.621 0.599 - 410.7 1 2 0 0.0025 16 0 0 0 0.00E+00 2.52E+08 - - - 5.8334 0.9935 221125_WJC_METTL3_EV_vs_WT_F08.22869.22869.4 4.72E-07 9/186 R.KINSSPNVNTTASGVEDLNIIQVTIPDDDNER.L "sp|P78347|GTF2I_HUMAN,tr|A0A494C1K3|A0A494C1K3_HUMAN" 2 3467.7016 1.6 123190 22869 4 3468.691244 867.9327 General transcription factor II-I OS=Homo sapiens OX=9606 GN=GTF2I PE=1 SV=2 3.96 3690.1 - 108610 - - - 285.389 - 2.091 0.549 - 25.5 1 2 0 0.9896 32 0 0 0 1.38E+06 8.63E+05 - - - 3.9531 0.9998 221125_WJC_METTL3_EV_vs_WT_F08.22871.22871.3 1.71E-05 10/124 R.AEQDSTTVAAFASSLVSGLNSSASEPAK[136.11]EPAK[136.11].K "sp|Q86U44|MTA70_HUMAN,tr|F5H6D8|F5H6D8_HUMAN,tr|H0YFV6|H0YFV6_HUMAN,tr|B4DTN4|B4DTN4_HUMAN" 4 3165.5648 0.001 123192 22871 3 3165.566392 1056.1956 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 4.41 3690.3 - 170932 - - - 0.4928 - 2.648 0.504 - 64.1 1 2 1 0.0016 32 0 0 0 0.00E+00 3.36E+06 - - - 6.399 0.9955 221125_WJC_METTL3_EV_vs_WT_F08.22872.22872.2 0.00476 18-Jun K.NGFLLDGFPR.T "sp|P54819|KAD2_HUMAN,tr|A0A5F9ZHP2|A0A5F9ZHP2_HUMAN,tr|G3V213|G3V213_HUMAN,tr|F8VY04|F8VY04_HUMAN,tr|F8W1A4|F8W1A4_HUMAN,tr|A0A5K1VW67|A0A5K1VW67_HUMAN,tr|F8VZG5|F8VZG5_HUMAN" 7 1134.5822 0.39 123193 22872 2 1134.586249 568.2984 "Adenylate kinase 2, mitochondrial OS=Homo sapiens OX=9606 GN=AK2 PE=1 SV=2" 5.84 3690.4 - 66646.8 - - - 3.574 - 1.367 0.388 - 78.2 1 2 0 0.0041 10 0 0 0 2.25E+06 5.69E+06 - - - 2.7781 0.7912 221125_WJC_METTL3_EV_vs_WT_F08.22882.22882.4 1.73 3/108 R.GLLQDDAHPTLVTYADHSK[136.11].L "sp|Q86U44|MTA70_HUMAN,tr|F5H6D8|F5H6D8_HUMAN,tr|H0YFV6|H0YFV6_HUMAN,tr|B4DTN4|B4DTN4_HUMAN" 4 2088.0367 0.001 123198 22882 4 2088.034982 523.0165 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 5.13 3691.7 - 94287.9 - - - -0.8386 - 0.964 0.224 - 4.4 23 2 0 -0.0018 19 0 0 0 0.00E+00 1.61E+06 - - - 0.125 1 221125_WJC_METTL3_EV_vs_WT_F08.22913.22913.4 2.61E-09 24/120 R.K[136.11]HAASDVDLEIESLLNQQSTK[136.11].E "sp|Q86U44|MTA70_HUMAN,tr|F5H6D8|F5H6D8_HUMAN,tr|H0YFV6|H0YFV6_HUMAN,tr|B4DTN4|B4DTN4_HUMAN" 4 2341.2096 0.01 123212 22913 4 2341.204288 586.3097 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 4.75 3696 - 878138 - - - -2.277 - 4.221 0.578 - 537.9 1 2 0 -0.0053 21 0 0 0 1.97E+05 2.12E+07 - - - 4.7316 0.9998 221125_WJC_METTL3_EV_vs_WT_F08.22914.22914.4 2.92E-06 16/168 K.HAVSDPSILDSLDLNEDER[166.11]EVLINNINR[166.11]R[166.11].L "sp|P05198|IF2A_HUMAN,tr|H0YJS4|H0YJS4_HUMAN,tr|G3V4T5|G3V4T5_HUMAN" 3 3375.7161 0.97 123213 22914 4 3375.708502 844.9363 Eukaryotic translation initiation factor 2 subunit 1 OS=Homo sapiens OX=9606 GN=EIF2S1 PE=1 SV=3 4.38 3696.2 - 417990 - - - -2.2567 - 2.773 0.526 - 59.5 1 2 1 -0.0076 29 0 0 0 9.84E+06 1.01E+07 - - - 4.1165 0.9997 221125_WJC_METTL3_EV_vs_WT_F08.22928.22928.2 0.000524 30-Oct K.K[136.11]VSQEILELLNTTTAK.E "sp|Q86U44|MTA70_HUMAN,tr|H0YFV6|H0YFV6_HUMAN" 2 1795.0182 - 123221 22928 2 1795.016392 898.5164 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 6.14 3698 - 273124 - - - -1.0239 - 2.114 0.411 - 177.5 1 2 0 -0.0018 16 0 0 0 - - - - - 3.9165 0.9996 221125_WJC_METTL3_EV_vs_WT_F08.22932.22932.4 0.000358 16/168 K.HAVSDPSILDSLDLNEDEREVLINNINRR.L "sp|P05198|IF2A_HUMAN,tr|H0YJS4|H0YJS4_HUMAN,tr|G3V4T5|G3V4T5_HUMAN" 3 3345.6913 0.97 123223 22932 4 3345.681254 837.4301 Eukaryotic translation initiation factor 2 subunit 1 OS=Homo sapiens OX=9606 GN=EIF2S1 PE=1 SV=3 4.38 3698.5 - 456853 - - - -3.0057 - 2.75 0.51 - 72.7 1 2 1 -0.0101 29 0 0 0 9.84E+06 1.01E+07 - - - 3.974 1 221125_WJC_METTL3_EV_vs_WT_F08.22947.22947.3 1.82E-06 Dec-92 K.QTQTFTTYSDNQPGVLIQVYEGER[166.11].A "sp|P11142|HSP7C_HUMAN,tr|E9PNE6|E9PNE6_HUMAN,tr|A8K7Q2|A8K7Q2_HUMAN,tr|E9PKE3|E9PKE3_HUMAN,tr|E9PS65|E9PS65_HUMAN" 5 2783.3278 0.01 123232 22947 3 2783.322924 928.7832 Heat shock cognate 71 kDa protein OS=Homo sapiens OX=9606 GN=HSPA8 PE=1 SV=1 4.14 3700.4 - 351182 - - - -1.7425 - 2.48 0.553 - 131.5 1 2 0 -0.0048 24 0 0 0 4.30E+04 5.44E+06 - - - 6.8136 0.9999 221125_WJC_METTL3_EV_vs_WT_F08.22950.22950.3 9.21E-05 Aug-52 K.K[136.11]GPGEVAGTVTGQK[136.11].R "sp|Q86U44|MTA70_HUMAN,tr|F5H6D8|F5H6D8_HUMAN,tr|H0YFV6|H0YFV6_HUMAN,tr|B4DTN4|B4DTN4_HUMAN" 4 1343.738 0.001 123233 22950 3 1343.736208 448.9199 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 8.59 3700.8 - 88329.7 - - - -1.318 - 1.594 0.502 - 96.4 1 2 0 -0.0018 14 0 0 0 0.00E+00 6.68E+06 - - - 5.3754 1 221125_WJC_METTL3_EV_vs_WT_F08.22954.22954.4 3.62E-10 31/174 R.HIADLAGNSEVILPVPAFNVINGGSHAGNK[136.11].L "sp|P06733|ENOA_HUMAN,tr|A0A2R8Y6G6|A0A2R8Y6G6_HUMAN,tr|K7EM90|K7EM90_HUMAN,tr|A0A2R8YEM5|A0A2R8YEM5_HUMAN" 4 3018.5767 1.62 123235 22954 4 3018.575417 755.6514 Alpha-enolase OS=Homo sapiens OX=9606 GN=ENO1 PE=1 SV=2 5.99 3701.2 - 467306 - - - -0.4144 - 4.769 0.635 - 271.8 1 2 0 -0.0013 30 0 0 0 4.36E+07 2.69E+07 - - - 5.2307 1 221125_WJC_METTL3_EV_vs_WT_F08.22969.22969.4 5.60E-14 17/102 R.SHTEEDC[160.03]TEELFDFLHAR.D sp|P07919|QCR6_HUMAN 1 2234.9539 0.97 123242 22969 4 2234.958127 559.7457 "Cytochrome b-c1 complex subunit 6, mitochondrial OS=Homo sapiens OX=9606 GN=UQCRH PE=1 SV=2" 4.35 3703.2 - 240765 - - - 1.9083 - 3.205 0.71 - 323.6 1 2 0 0.0043 18 0 0 0 2.89E+06 2.97E+06 - - - 5.8036 0.9992 221125_WJC_METTL3_EV_vs_WT_F08.22970.22970.4 0.000368 13/102 R.C[160.03]QHAAHIISELILTAQER[166.11].D sp|Q96I24|FUBP3_HUMAN 1 2099.0821 1.77 123243 22970 4 2099.080138 525.7778 Far upstream element-binding protein 3 OS=Homo sapiens OX=9606 GN=FUBP3 PE=1 SV=2 6 3703.4 - 69092.9 - - - -0.948 - 2.186 0.308 - 148.3 1 2 0 -0.002 18 0 0 0 3.28E+06 1.86E+06 - - - 2.1742 1 221125_WJC_METTL3_EV_vs_WT_F08.22975.22975.4 2.45E-13 39/174 R.HIADLAGNSEVILPVPAFNVINGGSHAGNK.L "sp|P06733|ENOA_HUMAN,tr|A0A2R8Y6G6|A0A2R8Y6G6_HUMAN,tr|K7EM90|K7EM90_HUMAN,tr|A0A2R8YEM5|A0A2R8YEM5_HUMAN" 4 3010.5625 1.62 123245 22975 4 3010.569366 753.6479 Alpha-enolase OS=Homo sapiens OX=9606 GN=ENO1 PE=1 SV=2 5.99 3704.1 - 1.78E+06 - - - 2.2913 - 6.037 0.691 - 859 1 2 0 0.0069 30 0 0 0 4.36E+07 2.69E+07 - - - 5.7887 1 221125_WJC_METTL3_EV_vs_WT_F08.22978.22978.3 7.87E-05 18/116 R.HIADLAGNSEVILPVPAFNVINGGSHAGNK.L "sp|P06733|ENOA_HUMAN,tr|A0A2R8Y6G6|A0A2R8Y6G6_HUMAN,tr|K7EM90|K7EM90_HUMAN,tr|A0A2R8YEM5|A0A2R8YEM5_HUMAN" 4 3010.5625 2.36 123247 22978 3 3010.5664 1004.5281 Alpha-enolase OS=Homo sapiens OX=9606 GN=ENO1 PE=1 SV=2 5.99 3704.5 - 161959 - - - 1.3061 - 3.746 0.608 - 256.5 1 2 0 0.0039 30 0 0 0 2.54E+06 1.07E+06 - - - 8.3559 1 221125_WJC_METTL3_EV_vs_WT_F08.22981.22981.4 1.05E-06 12/102 R.SHTEEDC[160.03]TEELFDFLHAR[166.11].D sp|P07919|QCR6_HUMAN 1 2244.9621 0.97 123248 22981 4 2244.965311 562.2478 "Cytochrome b-c1 complex subunit 6, mitochondrial OS=Homo sapiens OX=9606 GN=UQCRH PE=1 SV=2" 4.35 3704.9 - 185462 - - - 1.4161 - 2.645 0.568 - 151.8 1 2 0 0.0032 18 0 0 0 2.89E+06 2.97E+06 - - - 4.5022 0.9999 221125_WJC_METTL3_EV_vs_WT_F08.22982.22982.3 2.06E-08 16/68 R.C[160.03]QHAAHIISELILTAQER.D sp|Q96I24|FUBP3_HUMAN 1 2089.0739 6.54 123249 22982 3 2089.083549 697.3652 Far upstream element-binding protein 3 OS=Homo sapiens OX=9606 GN=FUBP3 PE=1 SV=2 6 3705 - 134727 - - - 4.6389 - 3.208 0.605 - 438.8 1 2 0 0.0097 18 0 0 0 1.20E+07 1.83E+06 - - - 8.185 1 221125_WJC_METTL3_EV_vs_WT_F08.22987.22987.3 3.33E-16 24/96 R.EQELHNLLEVVSQC[160.03]C[160.03]EASSSDITEK.S "sp|P52732|KIF11_HUMAN,tr|A0A7I2V3A9|A0A7I2V3A9_HUMAN" 2 2904.3117 6.03 123252 22987 3 2904.310311 969.1112 Kinesin-like protein KIF11 OS=Homo sapiens OX=9606 GN=KIF11 PE=1 SV=2 4.14 3705.7 - 346056 - - - -0.4845 - 4.269 0.801 - 813.4 1 2 0 -0.0014 25 0 0 0 4.26E+07 7.06E+06 - - - 10.8091 0.9998 221125_WJC_METTL3_EV_vs_WT_F08.22988.22988.4 8.79E-07 12/132 K.QSPSQANGC[160.03]SDHRPIDILEMLSR.A "sp|Q9NPI6|DCP1A_HUMAN,tr|A0A087WT55|A0A087WT55_HUMAN,tr|A0A087WVE6|A0A087WVE6_HUMAN" 3 2610.2279 2.4 123253 22988 4 2610.240215 653.5642 mRNA-decapping enzyme 1A OS=Homo sapiens OX=9606 GN=DCP1A PE=1 SV=3 5.38 3705.8 - 153415 - - - 4.7299 - 2.899 0.582 - 79.1 1 2 0 0.0123 23 0 0 0 7.43E+06 3.10E+06 - - - 4.6331 1 221125_WJC_METTL3_EV_vs_WT_F08.22998.22998.4 6.70E-13 18/144 R.EQELHNLLEVVSQC[160.03]C[160.03]EASSSDITEK.S "sp|P52732|KIF11_HUMAN,tr|A0A7I2V3A9|A0A7I2V3A9_HUMAN" 2 2904.3117 3.45 123259 22998 4 2904.318871 727.0852 Kinesin-like protein KIF11 OS=Homo sapiens OX=9606 GN=KIF11 PE=1 SV=2 4.14 3707.2 - 236044 - - - 2.4629 - 3.741 0.69 - 244.1 1 2 0 0.0072 25 0 0 0 7.47E+06 2.16E+06 - - - 5.6495 0.9999 221125_WJC_METTL3_EV_vs_WT_F08.22999.22999.3 2.75E-05 Nov-52 K.KQELEEILHDLESR.V sp|P35580|MYH10_HUMAN 1 1737.8897 0.07 123260 22999 3 1737.893912 580.3039 Myosin-10 OS=Homo sapiens OX=9606 GN=MYH10 PE=1 SV=3 4.57 3707.3 - 98793.7 - - - 2.4075 - 2.421 0.511 - 205.8 1 2 0 0.0042 14 0 0 0 4.48E+06 6.09E+07 - - - 6.5857 1 221125_WJC_METTL3_EV_vs_WT_F08.23005.23005.4 3.22E-07 12/132 K.QSPSQANGC[160.03]SDHR[166.11]PIDILEMLSR[166.11].A "sp|Q9NPI6|DCP1A_HUMAN,tr|A0A087WT55|A0A087WT55_HUMAN,tr|A0A087WVE6|A0A087WVE6_HUMAN" 3 2630.2444 2.41 123263 23005 4 2630.247378 658.5684 mRNA-decapping enzyme 1A OS=Homo sapiens OX=9606 GN=DCP1A PE=1 SV=3 5.38 3708.2 - 141173 - - - 1.1288 - 2.445 0.584 - 95.7 1 2 0 0.003 23 0 0 0 7.40E+06 3.07E+06 - - - 4.598 0.9996 221125_WJC_METTL3_EV_vs_WT_F08.23017.23017.3 0.000103 Aug-76 K.NNQFQALLQYADPVSAQHAK.L "sp|P26599|PTBP1_HUMAN,tr|A0A6Q8PEX4|A0A6Q8PEX4_HUMAN,tr|A0A0U1RRM4|A0A0U1RRM4_HUMAN,tr|A6NLN1|A6NLN1_HUMAN,tr|K7EKJ7|K7EKJ7_HUMAN,tr|A0A087WU68|A0A087WU68_HUMAN,tr|A0A7I2V4H6|A0A7I2V4H6_HUMAN,tr|A0A7I2V621|A0A7I2V621_HUMAN,tr|K7EK45|K7EK45_HUMAN" 9 2242.1131 1.44 123270 23017 3 2242.118859 748.3783 Polypyrimidine tract-binding protein 1 OS=Homo sapiens OX=9606 GN=PTBP1 PE=1 SV=1 6.74 3709.8 - 145153 - - - 2.5775 - 2.086 0.414 - 52.7 1 2 0 0.0058 20 0 0 0 4.47E+06 3.10E+06 - - - 4.9378 0.9991 221125_WJC_METTL3_EV_vs_WT_F08.23021.23021.4 0.0112 11/150 R.SFGTEDRPTDRPIPPRDEVFEYIIFR.G "sp|Q8ND56|LS14A_HUMAN,tr|I3L4Q1|I3L4Q1_HUMAN,tr|A0A140TA76|A0A140TA76_HUMAN,tr|K7EMZ9|K7EMZ9_HUMAN" 4 3151.5727 1 123272 23021 4 3151.57854 788.9005 Protein LSM14 homolog A OS=Homo sapiens OX=9606 GN=LSM14A PE=1 SV=3 4.59 3710.4 - 253137 - - - 1.8534 - 1.498 0.409 - 15.7 1 2 1 0.0058 26 0 0 0 2.17E+08 2.17E+08 - - - 2.9118 0.9699 221125_WJC_METTL3_EV_vs_WT_F08.23023.23023.3 0.00527 Jul-80 K.EQQSK[136.11]K[136.11]VSQEILELLNTTTAK[136.11].E "sp|Q86U44|MTA70_HUMAN,tr|H0YFV6|H0YFV6_HUMAN" 2 2411.3334 0.001 123273 23023 3 2411.344496 804.7851 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 6.33 3710.6 - 119457 - - - 4.614 - 1.579 0.371 - 39.2 1 2 1 0.0111 21 0 0 0 0.00E+00 3.12E+06 - - - 3.7683 0.9998 221125_WJC_METTL3_EV_vs_WT_F08.23025.23025.3 0.000121 Aug-76 K.NNQFQALLQYADPVSAQHAK[136.11].L "sp|P26599|PTBP1_HUMAN,tr|A0A6Q8PEX4|A0A6Q8PEX4_HUMAN,tr|A0A0U1RRM4|A0A0U1RRM4_HUMAN,tr|A6NLN1|A6NLN1_HUMAN,tr|K7EKJ7|K7EKJ7_HUMAN,tr|A0A087WU68|A0A087WU68_HUMAN,tr|A0A7I2V4H6|A0A7I2V4H6_HUMAN,tr|A0A7I2V621|A0A7I2V621_HUMAN,tr|K7EK45|K7EK45_HUMAN" 9 2250.1273 1.38 123274 23025 3 2250.131715 751.0497 Polypyrimidine tract-binding protein 1 OS=Homo sapiens OX=9606 GN=PTBP1 PE=1 SV=1 6.74 3710.9 - 130906 - - - 1.971 - 1.539 0.502 - 22.8 1 2 0 0.0044 20 0 0 0 4.29E+06 3.10E+06 - - - 5.1815 1 221125_WJC_METTL3_EV_vs_WT_F08.23027.23027.3 2.39E-08 11/120 R.GSDELFSTC[160.03]VTNGPFIMSSNSASAANGNDSK.K "sp|P26599|PTBP1_HUMAN,tr|A0A6Q8PEX4|A0A6Q8PEX4_HUMAN,tr|A0A0U1RRM4|A0A0U1RRM4_HUMAN,tr|K7EKJ7|K7EKJ7_HUMAN,tr|A0A7I2V4H6|A0A7I2V4H6_HUMAN,tr|A0A7I2V621|A0A7I2V621_HUMAN" 6 3164.3663 0.56 123276 23027 3 3164.365555 1055.796 Polypyrimidine tract-binding protein 1 OS=Homo sapiens OX=9606 GN=PTBP1 PE=1 SV=1 4.03 3711.1 - 120278 - - - -0.2266 - 3.02 0.702 - 111.9 1 2 0 -0.0007 31 0 0 0 3.92E+06 7.03E+06 - - - 8.9092 1 221125_WJC_METTL3_EV_vs_WT_F08.23033.23033.3 8.27E-09 16/120 R.GSDELFSTC[160.03]VTNGPFIMSSNSASAANGNDSK[136.11].K "sp|P26599|PTBP1_HUMAN,tr|A0A6Q8PEX4|A0A6Q8PEX4_HUMAN,tr|A0A0U1RRM4|A0A0U1RRM4_HUMAN,tr|K7EKJ7|K7EKJ7_HUMAN,tr|A0A7I2V4H6|A0A7I2V4H6_HUMAN,tr|A0A7I2V621|A0A7I2V621_HUMAN" 6 3172.3805 0.56 123280 23033 3 3172.383248 1058.4674 Polypyrimidine tract-binding protein 1 OS=Homo sapiens OX=9606 GN=PTBP1 PE=1 SV=1 4.03 3711.9 - 182287 - - - 0.8751 - 3.633 0.709 - 269.9 1 2 0 0.0028 31 0 0 0 3.92E+06 7.03E+06 - - - 9.4118 1 221125_WJC_METTL3_EV_vs_WT_F08.23036.23036.3 2.80E-08 19/96 R.EQELHNLLEVVSQC[160.03]C[160.03]EASSSDITEK[136.11].S "sp|P52732|KIF11_HUMAN,tr|A0A7I2V3A9|A0A7I2V3A9_HUMAN" 2 2912.3259 6.03 123281 23036 3 2912.323798 971.7826 Kinesin-like protein KIF11 OS=Homo sapiens OX=9606 GN=KIF11 PE=1 SV=2 4.14 3712.3 - 283902 - - - -0.7279 - 3.932 0.697 - 416.4 1 2 0 -0.0021 25 0 0 0 4.26E+07 7.06E+06 - - - 9.4602 0.9922 221125_WJC_METTL3_EV_vs_WT_F08.23043.23043.3 0.00133 Jul-96 R.HDSEQDNSDNNTIFVQGLGENVTIE.S sp|P35637|FUS_HUMAN 1 2774.2267 - 123284 23043 3 2774.228842 925.7495 RNA-binding protein FUS OS=Homo sapiens OX=9606 GN=FUS PE=1 SV=1 3.89 3713.4 - 133721 - - - 0.7631 - 1.243 0.577 - 27.7 1 1 0 0.0021 25 0 0 0 - - - - - 5.4728 1 221125_WJC_METTL3_EV_vs_WT_F08.23049.23049.3 1.30E-09 19/80 R.K[136.11]HAASDVDLEIESLLNQQSTK[136.11].E "sp|Q86U44|MTA70_HUMAN,tr|F5H6D8|F5H6D8_HUMAN,tr|H0YFV6|H0YFV6_HUMAN,tr|B4DTN4|B4DTN4_HUMAN" 4 2341.2096 0.04 123288 23049 3 2341.208252 781.4105 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 4.75 3714.2 - 486286 - - - -0.5839 - 4.085 0.565 - 459.6 1 2 0 -0.0014 21 0 0 0 2.17E+06 4.89E+07 - - - 8.2128 1 221125_WJC_METTL3_EV_vs_WT_F08.23052.23052.4 6.86E-07 10/216 K.KPGAGDTAFPGTGGFSATFDYQQAFGNSTGGFDGQAR.Q sp|Q96PK6|RBM14_HUMAN 1 3684.6506 2.71 123290 23052 4 3684.655934 922.1699 RNA-binding protein 14 OS=Homo sapiens OX=9606 GN=RBM14 PE=1 SV=2 4.43 3714.5 - 148890 - - - 1.4563 - 2.206 0.637 - 29 1 2 0 0.0054 37 0 0 0 2.88E+06 1.06E+06 - - - 5.0009 1 221125_WJC_METTL3_EV_vs_WT_F08.23063.23063.4 4.57E-13 30/144 K.TEEVK[136.11]QDK[136.11]DDIINIFSVASGHLYER[166.11].F sp|Q9NYU2|UGGG1_HUMAN 1 2931.4824 0.12 123293 23063 4 2931.487193 733.8779 UDP-glucose:glycoprotein glucosyltransferase 1 OS=Homo sapiens OX=9606 GN=UGGT1 PE=1 SV=3 4.58 3716.3 - 700294 - - - 1.6224 - 5.359 0.673 - 788.1 1 2 2 0.0048 25 0 0 0 3.22E+06 2.76E+07 - - - 5.6165 0.939 221125_WJC_METTL3_EV_vs_WT_F08.23074.23074.3 0.376 May-72 K.LGGSLADSYLDEGFLLDK[136.11]K[136.11].L "sp|P78371|TCPB_HUMAN,tr|F8VQ14|F8VQ14_HUMAN,tr|F5GWF6|F5GWF6_HUMAN" 3 2056.0699 0.27 123299 23074 3 2056.072132 686.3639 T-complex protein 1 subunit beta OS=Homo sapiens OX=9606 GN=CCT2 PE=1 SV=4 4.23 3717.8 - 93189.4 - - - 1.0671 - 0.947 0.216 - 19.9 1 2 0 0.0022 19 0 0 0 8.41E+05 3.16E+06 - - - 0.8138 1 221125_WJC_METTL3_EV_vs_WT_F08.23077.23077.3 1.93E-06 15/60 K.K[136.11]VSQEILELLNTTTAK[136.11].E "sp|Q86U44|MTA70_HUMAN,tr|H0YFV6|H0YFV6_HUMAN" 2 1803.0324 0.36 123300 23077 3 1803.034273 602.0181 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 6.14 3718.2 - 152891 - - - 1.0222 - 2.962 0.587 - 412.2 1 2 0 0.0018 16 0 0 0 4.79E+06 1.35E+07 - - - 7.8701 0.9997 221125_WJC_METTL3_EV_vs_WT_F08.23088.23088.3 0.00188 Jul-56 R.STSHK[136.11]PDEIYGMIER[166.11].L sp|Q86U44|MTA70_HUMAN 1 1779.8581 0.01 123308 23088 3 1779.860044 594.2933 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 5.42 3719.6 - 184589 - - - 1.1181 - 1.449 0.43 - 49.5 1 2 0 0.002 15 0 0 0 1.90E+05 1.43E+07 - - - 4.3013 1 221125_WJC_METTL3_EV_vs_WT_F08.23092.23092.3 2.29E-09 25/76 K.HAASDVDLEIESLLNQQSTK[136.11].E "sp|Q86U44|MTA70_HUMAN,tr|F5H6D8|F5H6D8_HUMAN,tr|H0YFV6|H0YFV6_HUMAN,tr|B4DTN4|B4DTN4_HUMAN" 4 2205.1005 0.02 123310 23092 3 2206.097468 736.0408 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 4.31 3720.1 - 1.66E+06 - - - 452.139 - 4.404 0.64 - 817.2 1 2 0 0.997 20 0 0 0 7.60E+07 3.05E+09 - - - 8.9958 1 221125_WJC_METTL3_EV_vs_WT_F08.23122.23122.2 3.74E-10 15/38 K.HAASDVDLEIESLLNQQSTK[136.11].E "sp|Q86U44|MTA70_HUMAN,tr|F5H6D8|F5H6D8_HUMAN,tr|H0YFV6|H0YFV6_HUMAN,tr|B4DTN4|B4DTN4_HUMAN" 4 2205.1005 0.001 123326 23122 2 2206.10074 1103.5575 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 4.31 3723.8 - 334468 - - - 453.6229 - 3.247 0.576 - 392.7 1 2 0 1.0003 20 0 0 0 0.00E+00 4.57E+07 - - - 5.8768 1 221125_WJC_METTL3_EV_vs_WT_F08.23136.23136.4 3.74E-09 16/114 K.HAASDVDLEIESLLNQQSTK[136.11].E "sp|Q86U44|MTA70_HUMAN,tr|F5H6D8|F5H6D8_HUMAN,tr|H0YFV6|H0YFV6_HUMAN,tr|B4DTN4|B4DTN4_HUMAN" 4 2205.1005 0.01 123334 23136 4 2205.094369 552.2824 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 4.31 3725.6 - 482378 - - - -2.7604 - 3.007 0.623 - 226.3 1 2 0 -0.0061 20 0 0 0 1.48E+05 1.64E+07 - - - 5.015 0.9999 221125_WJC_METTL3_EV_vs_WT_F08.23143.23143.4 1.68E-05 24/120 R.K[136.11]HAASDVDLEIESLLNQQSTK[136.11].E "sp|Q86U44|MTA70_HUMAN,tr|F5H6D8|F5H6D8_HUMAN,tr|H0YFV6|H0YFV6_HUMAN,tr|B4DTN4|B4DTN4_HUMAN" 4 2341.2096 0.01 123338 23143 4 2341.201757 586.3097 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 4.75 3726.5 - 1.09E+06 - - - -3.3581 - 4.546 0.55 - 487.7 1 2 0 -0.0079 21 0 0 0 6.09E+05 4.54E+07 - - - 4.5117 1 221125_WJC_METTL3_EV_vs_WT_F08.23146.23146.4 4.28E-13 22/192 R.TESSSDRIPVHQNGLSMNQMLMGLSPNVLPGPK.E sp|Q9UI36|DACH1_HUMAN 1 3533.7429 1.99 123340 23146 4 3533.735007 884.443 Dachshund homolog 1 OS=Homo sapiens OX=9606 GN=DACH1 PE=1 SV=4 6.42 3726.8 - 475685 - - - -2.2319 - 4.277 0.704 - 199.4 1 2 1 -0.0079 33 0 0 0 2.19E+07 1.10E+07 - - - 5.7875 0.9621 221125_WJC_METTL3_EV_vs_WT_F08.23166.23166.4 0.000195 17/168 K.NHGVVMPDANK[136.11]ENTLNQLVGAAFGAAGQR[166.11].C "sp|Q02252|MMSA_HUMAN,tr|G3V4Z4|G3V4Z4_HUMAN" 2 2996.5006 1.68 123348 23166 4 2997.493525 750.1324 "Methylmalonate-semialdehyde dehydrogenase [acylating], mitochondrial OS=Homo sapiens OX=9606 GN=ALDH6A1 PE=1 SV=2" 6.75 3729.7 - 257419 - - - 331.3759 - 2.911 0.473 - 107.7 1 2 1 0.993 29 0 0 0 1.16E+07 6.88E+06 - - - 3.3972 1 221125_WJC_METTL3_EV_vs_WT_F08.23174.23174.4 7.24E-07 15/192 R.TESSSDR[166.11]IPVHQNGLSMNQMLMGLSPNVLPGPK[136.11].E sp|Q9UI36|DACH1_HUMAN 1 3551.7654 2.64 123351 23174 4 3551.753789 888.9486 Dachshund homolog 1 OS=Homo sapiens OX=9606 GN=DACH1 PE=1 SV=4 6.42 3730.6 - 375019 - - - -3.2589 - 3.208 0.638 - 96.9 1 2 1 -0.0116 33 0 0 0 2.14E+07 8.13E+06 - - - 5.1257 1 221125_WJC_METTL3_EV_vs_WT_F08.23177.23177.4 1.07E-12 25/168 K.NHGVVMPDANKENTLNQLVGAAFGAAGQR.C "sp|Q02252|MMSA_HUMAN,tr|G3V4Z4|G3V4Z4_HUMAN" 2 2978.4781 1.68 123352 23177 4 2978.467987 745.6268 "Methylmalonate-semialdehyde dehydrogenase [acylating], mitochondrial OS=Homo sapiens OX=9606 GN=ALDH6A1 PE=1 SV=2" 6.75 3731 - 460001 - - - -3.391 - 3.802 0.69 - 397.7 1 2 1 -0.0101 29 0 0 0 1.16E+07 6.88E+06 - - - 5.6406 1 221125_WJC_METTL3_EV_vs_WT_F08.23193.23193.3 0.00128 13/64 K.HVINFDLPSDIEEYVHR.L "sp|O00571|DDX3X_HUMAN,sp|O15523|DDX3Y_HUMAN,tr|A0A2R8YFR4|A0A2R8YFR4_HUMAN,tr|A0A2R8YCW1|A0A2R8YCW1_HUMAN,tr|A0A2R8YDT5|A0A2R8YDT5_HUMAN,tr|A0A2R8Y645|A0A2R8Y645_HUMAN,tr|A0A2R8YF78|A0A2R8YF78_HUMAN,tr|A0A0D9SFB3|A0A0D9SFB3_HUMAN,tr|A0A2R8YFS5|A0A2R8YFS5_HUMAN,tr|A0A0D9SF53|A0A0D9SF53_HUMAN,tr|A0A087WVZ1|A0A087WVZ1_HUMAN,tr|A0A0J9YVQ7|A0A0J9YVQ7_HUMAN,tr|A0A2R8Y5G6|A0A2R8Y5G6_HUMAN,tr|A0A2R8Y7T2|A0A2R8Y7T2_HUMAN,tr|A0A0D9SG12|A0A0D9SG12_HUMAN,tr|F6S8Q4|F6S8Q4_HUMAN,tr|A0A2U3TZJ9|A0A2U3TZJ9_HUMAN,tr|A0A2R8Y4A4|A0A2R8Y4A4_HUMAN" 18 2082.0171 0.9 123361 23193 3 2082.014455 695.013 ATP-dependent RNA helicase DDX3X OS=Homo sapiens OX=9606 GN=DDX3X PE=1 SV=3 4.72 3733.2 - 190516 - - - -1.2483 - 3.043 0.552 - 254.1 1 2 0 -0.0026 17 0 0 0 3.61E+06 4.01E+06 - - - 7.5049 1 221125_WJC_METTL3_EV_vs_WT_F08.23199.23199.4 5.90E-09 14/96 K.HVINFDLPSDIEEYVHR.L "sp|O00571|DDX3X_HUMAN,sp|O15523|DDX3Y_HUMAN,tr|A0A2R8YFR4|A0A2R8YFR4_HUMAN,tr|A0A2R8YCW1|A0A2R8YCW1_HUMAN,tr|A0A2R8YDT5|A0A2R8YDT5_HUMAN,tr|A0A2R8Y645|A0A2R8Y645_HUMAN,tr|A0A2R8YF78|A0A2R8YF78_HUMAN,tr|A0A0D9SFB3|A0A0D9SFB3_HUMAN,tr|A0A2R8YFS5|A0A2R8YFS5_HUMAN,tr|A0A0D9SF53|A0A0D9SF53_HUMAN,tr|A0A087WVZ1|A0A087WVZ1_HUMAN,tr|A0A0J9YVQ7|A0A0J9YVQ7_HUMAN,tr|A0A2R8Y5G6|A0A2R8Y5G6_HUMAN,tr|A0A2R8Y7T2|A0A2R8Y7T2_HUMAN,tr|A0A0D9SG12|A0A0D9SG12_HUMAN,tr|F6S8Q4|F6S8Q4_HUMAN,tr|A0A2U3TZJ9|A0A2U3TZJ9_HUMAN,tr|A0A2R8Y4A4|A0A2R8Y4A4_HUMAN" 18 2082.0171 1.17 123363 23199 4 2082.017044 521.5115 ATP-dependent RNA helicase DDX3X OS=Homo sapiens OX=9606 GN=DDX3X PE=1 SV=3 4.72 3734.1 - 83325.4 - - - -0.0048 - 2.731 0.631 - 171.6 1 2 0 0 17 0 0 0 3.21E+06 2.75E+06 - - - 5.067 0.9997 221125_WJC_METTL3_EV_vs_WT_F08.23213.23213.2 0.00125 18-Jul K.ILLAELEQLK[136.11].G "sp|P08670|VIME_HUMAN,tr|B0YJC4|B0YJC4_HUMAN,tr|A0A1B0GTT5|A0A1B0GTT5_HUMAN" 3 1176.7209 1.95 123372 23213 2 1176.720017 589.3677 Vimentin OS=Homo sapiens OX=9606 GN=VIM PE=1 SV=4 4.53 3735.8 - 111608 - - - -0.7716 - 1.665 0.422 - 98.6 1 2 0 -0.0009 10 0 0 0 6.97E+06 3.57E+06 - - - 3.5807 0.9978 221125_WJC_METTL3_EV_vs_WT_F08.23231.23231.4 0.00447 5/174 R.TNLDESDVQPVK[136.11]EQLAQAMFDHIPVGVGSK[136.11].G sp|Q9Y3I0|RTCB_HUMAN 1 3267.6416 3.68 123379 23231 4 3267.641854 817.9177 RNA-splicing ligase RtcB homolog OS=Homo sapiens OX=9606 GN=RTCB PE=1 SV=1 4.43 3738.3 - 136897 - - - 0.0646 - 1.253 0.346 - 8.1 1 2 1 0.0002 30 0 0 0 1.06E+07 2.89E+06 - - - 2.3065 0.9963 221125_WJC_METTL3_EV_vs_WT_F08.23233.23233.4 0.0601 5/108 R.GLLQDDAHPTLVTYADHSK[136.11].L "sp|Q86U44|MTA70_HUMAN,tr|F5H6D8|F5H6D8_HUMAN,tr|H0YFV6|H0YFV6_HUMAN,tr|B4DTN4|B4DTN4_HUMAN" 4 2088.0367 0.42 123380 23233 4 2088.035072 523.0165 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 5.13 3738.5 - 91481.1 - - - -0.7955 - 1.163 0.259 - 12.4 1 2 0 -0.0017 19 0 0 0 2.86E+06 6.79E+06 - - - 1.531 0.993 221125_WJC_METTL3_EV_vs_WT_F08.23237.23237.2 1.68E-05 28-Dec D.VDLEIESLLNQQSTK[136.11].E "sp|Q86U44|MTA70_HUMAN,tr|F5H6D8|F5H6D8_HUMAN,tr|H0YFV6|H0YFV6_HUMAN,tr|B4DTN4|B4DTN4_HUMAN" 4 1723.9083 0.001 123382 23237 2 1723.90605 862.9614 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 4.14 3739 - 187066 - - - -1.3313 - 2.778 0.558 - 553 1 1 0 -0.0023 15 0 0 0 0.00E+00 1.64E+07 - - - 5.6736 1 221125_WJC_METTL3_EV_vs_WT_F08.23242.23242.3 5.63E-10 Dec-88 R.RDNYVPEVSALDQEIIEVDPDTK.E "sp|P08708|RS17_HUMAN,tr|H3BNC9|H3BNC9_HUMAN,tr|H0YN88|H0YN88_HUMAN,tr|A0A075B716|A0A075B716_HUMAN" 4 2644.2868 0.87 123385 23242 3 2644.280143 882.4362 40S ribosomal protein S17 OS=Homo sapiens OX=9606 GN=RPS17 PE=1 SV=2 3.9 3739.7 - 133529 - - - -2.5198 - 3.211 0.645 - 118.4 1 2 0 -0.0067 23 0 0 0 5.18E+06 5.95E+06 - - - 8.466 0.9999 221125_WJC_METTL3_EV_vs_WT_F08.23243.23243.4 6.04E-06 12/162 R.GPLPLSSQHR[166.11]GDADQASNILASFGLSAR[166.11].D "sp|P43243|MATR3_HUMAN,tr|A8MXP9|A8MXP9_HUMAN,tr|D6R991|D6R991_HUMAN,tr|A0A0R4J2E8|A0A0R4J2E8_HUMAN,tr|D6REM6|D6REM6_HUMAN" 5 2884.4695 1.34 123386 23243 4 2884.469414 722.1246 Matrin-3 OS=Homo sapiens OX=9606 GN=MATR3 PE=1 SV=2 6.75 3739.8 - 160960 - - - -0.0153 - 2.221 0.571 - 75 1 2 1 0 28 0 0 0 1.29E+07 9.63E+06 - - - 4.4437 1 221125_WJC_METTL3_EV_vs_WT_F08.23248.23248.4 8.92E-09 20/150 R.SFGTEDRPTDRPIPPRDEVFEYIIFR.G "sp|Q8ND56|LS14A_HUMAN,tr|I3L4Q1|I3L4Q1_HUMAN,tr|A0A140TA76|A0A140TA76_HUMAN,tr|K7EMZ9|K7EMZ9_HUMAN" 4 3151.5727 1 123387 23248 4 3151.572811 788.9005 Protein LSM14 homolog A OS=Homo sapiens OX=9606 GN=LSM14A PE=1 SV=3 4.59 3740.6 - 775561 - - - 0.0355 - 3.431 0.64 - 56.4 1 2 1 0.0001 26 0 0 0 2.16E+08 2.16E+08 - - - 5.1854 0.9999 221125_WJC_METTL3_EV_vs_WT_F08.23250.23250.3 0.00017 Jul-52 K.K[136.11]GPGEVAGTVTGQK[136.11].R "sp|Q86U44|MTA70_HUMAN,tr|F5H6D8|F5H6D8_HUMAN,tr|H0YFV6|H0YFV6_HUMAN,tr|B4DTN4|B4DTN4_HUMAN" 4 1343.738 0 123389 23250 3 1343.738919 448.9199 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 8.59 3740.8 - 88663.8 - - - 0.6995 - 1.636 0.501 - 68.7 1 2 0 0.0009 14 0 0 0 2.15E+04 5.50E+06 - - - 5.4336 0.9999 221125_WJC_METTL3_EV_vs_WT_F08.23264.23264.3 2.15E-05 9/128 R.SDSPVPTAPTSGGPK[136.11]PSTASAVPELATDPELEK[136.11].K "sp|Q86U44|MTA70_HUMAN,tr|B4E349|B4E349_HUMAN,tr|F5H6D8|F5H6D8_HUMAN,tr|B4DTN4|B4DTN4_HUMAN" 4 3248.6271 0.001 123395 23264 3 3248.633053 1083.883 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 4.18 3742.9 - 162166 - - - 1.8331 - 1.953 0.513 - 38.6 1 2 0 0.006 33 0 0 0 0.00E+00 1.77E+07 - - - 5.7978 0.9992 221125_WJC_METTL3_EV_vs_WT_F08.23267.23267.2 3.66E-06 Jul-32 R.STGEAFVQFASQEIAEK[136.11].A "sp|P55795|HNRH2_HUMAN,sp|P31943|HNRH1_HUMAN,tr|E5RGH4|E5RGH4_HUMAN,tr|H0YB39|H0YB39_HUMAN,tr|E5RGV0|E5RGV0_HUMAN,tr|E9PCY7|E9PCY7_HUMAN,tr|D6RIU0|D6RIU0_HUMAN,tr|D6RBM0|D6RBM0_HUMAN,tr|G8JLB6|G8JLB6_HUMAN,tr|E7EN40|E7EN40_HUMAN" 10 1848.8985 0.66 123396 23267 2 1848.902032 925.4565 Heterogeneous nuclear ribonucleoprotein H2 OS=Homo sapiens OX=9606 GN=HNRNPH2 PE=1 SV=1 4.25 3743.3 - 90562.4 - - - 1.9055 - 1.655 0.42 - 90.2 1 2 0 0.0035 17 0 0 0 1.67E+06 2.52E+06 - - - 3.3806 0.9998 221125_WJC_METTL3_EV_vs_WT_F08.23273.23273.2 0.00512 Sep-32 R.STGEAFVQFASQEIAEK.A "sp|P55795|HNRH2_HUMAN,sp|P31943|HNRH1_HUMAN,tr|E5RGH4|E5RGH4_HUMAN,tr|H0YB39|H0YB39_HUMAN,tr|E5RGV0|E5RGV0_HUMAN,tr|E9PCY7|E9PCY7_HUMAN,tr|D6RIU0|D6RIU0_HUMAN,tr|D6RBM0|D6RBM0_HUMAN,tr|G8JLB6|G8JLB6_HUMAN,tr|E7EN40|E7EN40_HUMAN" 10 1840.8843 0.66 123400 23273 2 1840.886195 921.4494 Heterogeneous nuclear ribonucleoprotein H2 OS=Homo sapiens OX=9606 GN=HNRNPH2 PE=1 SV=1 4.25 3744.1 - 67995.2 - - - 1.0245 - 2.116 0.496 - 186.2 1 2 0 0.0019 17 0 0 0 1.67E+06 2.52E+06 - - - 4.5466 0.9984 221125_WJC_METTL3_EV_vs_WT_F08.23278.23278.2 0.00273 May-32 R.STGEAFVQFASQEIAEK.A "sp|P55795|HNRH2_HUMAN,sp|P31943|HNRH1_HUMAN,tr|E5RGH4|E5RGH4_HUMAN,tr|H0YB39|H0YB39_HUMAN,tr|E5RGV0|E5RGV0_HUMAN,tr|E9PCY7|E9PCY7_HUMAN,tr|D6RIU0|D6RIU0_HUMAN,tr|D6RBM0|D6RBM0_HUMAN,tr|G8JLB6|G8JLB6_HUMAN,tr|E7EN40|E7EN40_HUMAN" 10 1840.8843 0.66 123402 23278 2 1840.886876 921.4494 Heterogeneous nuclear ribonucleoprotein H2 OS=Homo sapiens OX=9606 GN=HNRNPH2 PE=1 SV=1 4.25 3744.7 - 63923.3 - - - 1.3944 - 1.358 0.353 - 80.3 1 2 0 0.0026 17 0 0 0 1.67E+06 2.52E+06 - - - 2.3998 0.9999 221125_WJC_METTL3_EV_vs_WT_F08.23286.23286.3 8.86E-06 Oct-64 K.VTLENFYSNLIAQHEER.E sp|Q15208|STK38_HUMAN 1 2062.012 7.83 123406 23286 3 2062.009434 688.3446 Serine\threonine-protein kinase 38 OS=Homo sapiens OX=9606 GN=STK38 PE=1 SV=1 4.75 3745.9 - 138938 - - - -1.2294 - 2.433 0.462 - 98.8 1 2 0 -0.0025 17 0 0 0 5.76E+06 7.35E+05 - - - 5.9363 0.9982 221125_WJC_METTL3_EV_vs_WT_F08.23293.23293.4 0.00163 8/126 R.ESEEENLNKSEISQVFEIALKR.N "sp|O95793|STAU1_HUMAN,tr|Q5JW30|Q5JW30_HUMAN,tr|Q5JW28|Q5JW28_HUMAN" 3 2591.3079 7.64 123408 23293 4 2591.310849 648.8342 Double-stranded RNA-binding protein Staufen homolog 1 OS=Homo sapiens OX=9606 GN=STAU1 PE=1 SV=2 4.48 3746.9 - 138286 - - - 1.1473 - 1.437 0.353 - 24.2 1 2 1 0.003 22 0 0 0 3.39E+06 4.44E+05 - - - 2.4163 1 221125_WJC_METTL3_EV_vs_WT_F08.23306.23306.4 0.000396 9/126 K.NPDDPDMVDVFMDHLDIDHNKK.L sp|P20930|FILA_HUMAN 1 2609.1526 49.63 123415 23306 4 2609.158133 653.2954 Filaggrin OS=Homo sapiens OX=9606 GN=FLG PE=1 SV=3 4.21 3748.7 - 124567 - - - 2.106 - 1.825 0.544 - 60.4 1 2 0 0.0055 22 0 0 0 1.40E+07 2.82E+05 - - - 4.1563 0.9976 221125_WJC_METTL3_EV_vs_WT_F08.23313.23313.3 0.0702 Apr-60 K.K[136.11]VSQEILELLNTTTAK[136.11].E "sp|Q86U44|MTA70_HUMAN,tr|H0YFV6|H0YFV6_HUMAN" 2 1803.0324 0.03 123420 23313 3 1803.030138 602.0181 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 6.14 3749.6 - 58420.6 - - - -1.2712 - 1.163 0.375 - 10.8 5 2 0 -0.0023 16 0 0 0 1.18E+05 4.40E+06 - - - 2.7842 0.9999 221125_WJC_METTL3_EV_vs_WT_F08.23317.23317.3 0.000517 Oct-56 R.STSHK[136.11]PDEIYGMIER[166.11].L sp|Q86U44|MTA70_HUMAN 1 1779.8581 0.04 123422 23317 3 1779.859201 594.2933 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 5.42 3750.1 - 150918 - - - 0.6444 - 1.787 0.496 - 124.2 1 2 0 0.0011 15 0 0 0 6.20E+05 1.63E+07 - - - 5.5844 0.9999 221125_WJC_METTL3_EV_vs_WT_F08.23323.23323.4 6.78E-06 10/162 R.GPLPLSSQHRGDADQASNILASFGLSAR.D "sp|P43243|MATR3_HUMAN,tr|A8MXP9|A8MXP9_HUMAN,tr|D6R991|D6R991_HUMAN,tr|A0A0R4J2E8|A0A0R4J2E8_HUMAN,tr|D6REM6|D6REM6_HUMAN" 5 2864.4529 1.34 123426 23323 4 2864.456384 717.1205 Matrin-3 OS=Homo sapiens OX=9606 GN=MATR3 PE=1 SV=2 6.75 3750.9 - 132855 - - - 1.21 - 2.382 0.56 - 57.2 1 2 1 0.0035 28 0 0 0 1.29E+07 9.63E+06 - - - 4.3688 0.9988 221125_WJC_METTL3_EV_vs_WT_F08.23324.23324.4 0.00104 10/144 K.GMSVSDLADKLSTDDLNSLIAHAHR.R "sp|Q16891|MIC60_HUMAN,tr|B9A067|B9A067_HUMAN,tr|C9J406|C9J406_HUMAN,tr|H7C463|H7C463_HUMAN" 4 2665.313 1.6 123427 23324 4 2665.319854 667.3355 MICOS complex subunit MIC60 OS=Homo sapiens OX=9606 GN=IMMT PE=1 SV=1 5.2 3751.1 - 145762 - - - 2.5798 - 2.251 0.408 - 61.7 1 2 1 0.0069 25 0 0 0 9.46E+06 5.89E+06 - - - 3.0334 0.9934 221125_WJC_METTL3_EV_vs_WT_F08.23334.23334.2 0.0137 May-38 R.ISLGLPVGAVINC[160.03]ADNTGAK[136.11].N "sp|P62829|RL23_HUMAN,tr|J3KT29|J3KT29_HUMAN,tr|B9ZVP7|B9ZVP7_HUMAN,tr|C9JD32|C9JD32_HUMAN" 4 1977.0445 1.33 123433 23334 2 1977.038194 989.5295 60S ribosomal protein L23 OS=Homo sapiens OX=9606 GN=RPL23 PE=1 SV=1 5.83 3752.4 - 67837.2 - - - -3.1704 - 1.321 0.345 - 48 2 2 0 -0.0063 20 0 0 0 1.25E+06 9.42E+05 - - - 2.1372 0.9996 221125_WJC_METTL3_EV_vs_WT_F08.23341.23341.3 0.000399 Jul-76 R.ISLGLPVGAVINC[160.03]ADNTGAK.N "sp|P62829|RL23_HUMAN,tr|J3KT29|J3KT29_HUMAN,tr|B9ZVP7|B9ZVP7_HUMAN,tr|C9JD32|C9JD32_HUMAN" 4 1969.0303 1.01 123437 23341 3 1969.032051 657.3507 60S ribosomal protein L23 OS=Homo sapiens OX=9606 GN=RPL23 PE=1 SV=1 5.83 3753.5 - 132531 - - - 0.9086 - 1.618 0.388 - 31 1 2 0 0.0018 20 0 0 0 3.51E+06 3.48E+06 - - - 4.0327 0.9999 221125_WJC_METTL3_EV_vs_WT_F08.23364.23364.4 5.48E-07 15/144 K.GMSVSDLADK[136.11]LSTDDLNSLIAHAHR[166.11].R "sp|Q16891|MIC60_HUMAN,tr|B9A067|B9A067_HUMAN,tr|C9J406|C9J406_HUMAN,tr|H7C463|H7C463_HUMAN" 4 2683.3354 1.62 123449 23364 4 2683.339785 671.8411 MICOS complex subunit MIC60 OS=Homo sapiens OX=9606 GN=IMMT PE=1 SV=1 5.2 3756.5 - 308463 - - - 1.6163 - 3.139 0.571 - 138.3 1 2 1 0.0043 25 0 0 0 9.42E+06 5.83E+06 - - - 4.5587 0.9998 221125_WJC_METTL3_EV_vs_WT_F08.23384.23384.4 0.00122 10/126 K.TSQLLETLNQLSTHTHVVDITR.T "sp|Q14203|DCTN1_HUMAN,tr|A0A804CDA6|A0A804CDA6_HUMAN,tr|E7EX90|E7EX90_HUMAN,tr|A0A7P0Z4C3|A0A7P0Z4C3_HUMAN,tr|E7EWF7|E7EWF7_HUMAN" 5 2505.3187 2.32 123461 23384 4 2505.3238 627.337 Dynactin subunit 1 OS=Homo sapiens OX=9606 GN=DCTN1 PE=1 SV=3 5.92 3759.1 - 188714 - - - 2.0293 - 2.358 0.399 - 56 1 2 0 0.0051 22 0 0 0 4.85E+06 2.09E+06 - - - 2.9782 1 221125_WJC_METTL3_EV_vs_WT_F08.23387.23387.3 7.59E-07 13/116 K.TGSSSPPGGPPK[136.11]PGSQLDSMLGSLQSDLNK[136.11].L "sp|P49023|PAXI_HUMAN,tr|F5GZ78|F5GZ78_HUMAN,tr|A0A1B0GTU4|A0A1B0GTU4_HUMAN" 3 2954.4626 0.72 123462 23387 3 2954.458578 985.8281 Paxillin OS=Homo sapiens OX=9606 GN=PXN PE=1 SV=3 5.63 3759.5 - 157930 - - - -1.3667 - 2.579 0.5 - 107.2 1 2 0 -0.004 30 0 0 0 1.25E+06 1.75E+06 - - - 6.293 1 221125_WJC_METTL3_EV_vs_WT_F08.23389.23389.4 6.03E-05 14/114 R.HNHDLSSYQDTIQQLENELR[166.11].G "sp|P07197|NFM_HUMAN,tr|E7ESP9|E7ESP9_HUMAN,tr|E7EMV2|E7EMV2_HUMAN" 3 2449.1497 3.5 123464 23389 4 2449.150528 613.2947 Neurofilament medium polypeptide OS=Homo sapiens OX=9606 GN=NEFM PE=1 SV=3 4.72 3759.8 - 215384 - - - 0.3181 - 2.491 0.511 - 64.2 1 2 0 0.0008 20 0 0 0 7.18E+07 2.05E+07 - - - 3.9787 0.9999 221125_WJC_METTL3_EV_vs_WT_F08.23403.23403.4 1.01E-06 18/210 R.EGNQEVPFDVPELWYEDEK[136.11]HSLNSSSASTTEPDFQK[136.11].D "sp|P42704|LPPRC_HUMAN,tr|A0A804HI14|A0A804HI14_HUMAN,tr|A0A804HL40|A0A804HL40_HUMAN,tr|A0A804HKJ0|A0A804HKJ0_HUMAN,tr|A0A804HKR3|A0A804HKR3_HUMAN,tr|A0A804HIN4|A0A804HIN4_HUMAN,tr|A0A804HI40|A0A804HI40_HUMAN,tr|A0A804HJZ1|A0A804HJZ1_HUMAN,tr|A0A804HIQ7|A0A804HIQ7_HUMAN,tr|A0A804HK30|A0A804HK30_HUMAN,tr|A0A804HKI2|A0A804HKI2_HUMAN,tr|A0A804HJI0|A0A804HJI0_HUMAN,tr|A0A804HIG4|A0A804HIG4_HUMAN" 13 4154.884 0.78 123474 23403 4 4154.883177 1039.7283 "Leucine-rich PPR motif-containing protein, mitochondrial OS=Homo sapiens OX=9606 GN=LRPPRC PE=1 SV=3" 4.05 3761.6 - 398523 - - - -0.1966 - 2.868 0.554 - 64.1 1 2 1 -0.0008 36 0 0 0 7.99E+06 1.02E+07 - - - 4.3584 1 221125_WJC_METTL3_EV_vs_WT_F08.23404.23404.3 4.26E-10 21/76 R.HNHDLSSYQDTIQQLENELR.G "sp|P07197|NFM_HUMAN,tr|E7ESP9|E7ESP9_HUMAN,tr|E7EMV2|E7EMV2_HUMAN" 3 2439.1415 2.76 123475 23404 3 2439.142202 814.0544 Neurofilament medium polypeptide OS=Homo sapiens OX=9606 GN=NEFM PE=1 SV=3 4.72 3761.7 - 690354 - - - 0.2964 - 3.532 0.652 - 455.7 1 2 0 0.0007 20 0 0 0 3.08E+07 1.11E+07 - - - 8.8703 1 221125_WJC_METTL3_EV_vs_WT_F08.23405.23405.3 3.03E-11 21/76 R.HNHDLSSYQDTIQQLENELR[166.11].G "sp|P07197|NFM_HUMAN,tr|E7ESP9|E7ESP9_HUMAN,tr|E7EMV2|E7EMV2_HUMAN" 3 2449.1497 2.78 123476 23405 3 2449.149572 817.3905 Neurofilament medium polypeptide OS=Homo sapiens OX=9606 GN=NEFM PE=1 SV=3 4.72 3761.8 - 261755 - - - -0.0723 - 4.139 0.686 - 657.9 1 2 0 -0.0002 20 0 0 0 3.06E+07 1.10E+07 - - - 9.6342 0.9642 221125_WJC_METTL3_EV_vs_WT_F08.23410.23410.2 0.09 14-Aug K.DIGFIKLD.- "sp|P62273|RS29_HUMAN,tr|A0A087WTT6|A0A087WTT6_HUMAN" 2 919.5015 1.11 123479 23410 2 919.501005 460.758 40S ribosomal protein S29 OS=Homo sapiens OX=9606 GN=RPS29 PE=1 SV=2 4.54 3762.5 - 412771 - - - -0.5209 - 1.241 0.235 - 129.2 1 2 1 -0.0005 8 0 0 0 6.64E+06 6.00E+06 - - - 1.4278 0.9999 221125_WJC_METTL3_EV_vs_WT_F08.23411.23411.4 1.24E-09 17/210 R.EGNQEVPFDVPELWYEDEKHSLNSSSASTTEPDFQK.D "sp|P42704|LPPRC_HUMAN,tr|A0A804HI14|A0A804HI14_HUMAN,tr|A0A804HL40|A0A804HL40_HUMAN,tr|A0A804HKJ0|A0A804HKJ0_HUMAN,tr|A0A804HKR3|A0A804HKR3_HUMAN,tr|A0A804HIN4|A0A804HIN4_HUMAN,tr|A0A804HI40|A0A804HI40_HUMAN,tr|A0A804HJZ1|A0A804HJZ1_HUMAN,tr|A0A804HIQ7|A0A804HIQ7_HUMAN,tr|A0A804HK30|A0A804HK30_HUMAN,tr|A0A804HKI2|A0A804HKI2_HUMAN,tr|A0A804HJI0|A0A804HJI0_HUMAN,tr|A0A804HIG4|A0A804HIG4_HUMAN" 13 4138.8556 0.78 123480 23411 4 4138.855984 1035.7212 "Leucine-rich PPR motif-containing protein, mitochondrial OS=Homo sapiens OX=9606 GN=LRPPRC PE=1 SV=3" 4.05 3762.6 - 303560 - - - 0.0942 - 3.249 0.59 - 65.7 1 2 1 0.0004 36 0 0 0 7.99E+06 1.02E+07 - - - 4.7086 0.9968 221125_WJC_METTL3_EV_vs_WT_F08.23412.23412.3 0.00011 Nov-52 V.DLEIESLLNQQSTK[136.11].E "sp|Q86U44|MTA70_HUMAN,tr|F5H6D8|F5H6D8_HUMAN,tr|H0YFV6|H0YFV6_HUMAN,tr|B4DTN4|B4DTN4_HUMAN" 4 1624.8399 0.01 123481 23412 3 1624.840631 542.6206 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 4.14 3762.8 - 623443 - - - 0.4308 - 2.586 0.486 - 120.8 1 1 0 0.0007 14 0 0 0 6.86E+04 9.35E+06 - - - 6.4832 0.9995 221125_WJC_METTL3_EV_vs_WT_F08.23418.23418.3 0.0193 Sep-56 R.DYLHLPPEIVPATLR[166.11].R "sp|P46783|RS10_HUMAN,tr|A0A2R8Y6L3|A0A2R8Y6L3_HUMAN,tr|F6U211|F6U211_HUMAN,tr|A0A1W2PQS6|A0A1W2PQS6_HUMAN,tr|A0A2R8YFH6|A0A2R8YFH6_HUMAN,tr|A0A2R8Y7H1|A0A2R8Y7H1_HUMAN,tr|S4R435|S4R435_HUMAN" 7 1742.9595 1.36 123487 23418 3 1742.961618 581.9938 40S ribosomal protein S10 OS=Homo sapiens OX=9606 GN=RPS10 PE=1 SV=1 5.32 3763.5 - 91272.9 - - - 1.2289 - 1.859 0.344 - 95.5 1 2 0 0.0021 15 0 0 0 7.57E+06 5.55E+06 - - - 3.9926 1 221125_WJC_METTL3_EV_vs_WT_F08.23419.23419.3 2.32E-05 Oct-56 R.DYLHLPPEIVPATLR.R "sp|P46783|RS10_HUMAN,tr|A0A2R8Y6L3|A0A2R8Y6L3_HUMAN,tr|F6U211|F6U211_HUMAN,tr|A0A1W2PQS6|A0A1W2PQS6_HUMAN,tr|A0A2R8YFH6|A0A2R8YFH6_HUMAN,tr|A0A2R8Y7H1|A0A2R8Y7H1_HUMAN,tr|S4R435|S4R435_HUMAN" 7 1732.9512 1.38 123488 23419 3 1732.95029 578.6577 40S ribosomal protein S10 OS=Homo sapiens OX=9606 GN=RPS10 PE=1 SV=1 5.32 3763.7 - 80263.6 - - - -0.5286 - 2.042 0.544 - 99.7 1 2 0 -0.0009 15 0 0 0 9.17E+06 6.63E+06 - - - 6.4677 1 221125_WJC_METTL3_EV_vs_WT_F08.23422.23422.3 1.40E-14 21/104 R.SSSPSDSDTSGFSSGSDHLSDLISSLR.L "sp|Q9BZB8|CPEB1_HUMAN,tr|A0A087X171|A0A087X171_HUMAN,tr|A0A087WXG7|A0A087WXG7_HUMAN,tr|A0A0J9YXP0|A0A0J9YXP0_HUMAN,tr|H3BNC9|H3BNC9_HUMAN,tr|A0A087WVR7|A0A087WVR7_HUMAN,tr|A0A024R214|A0A024R214_HUMAN" 7 2727.2107 1.18 123489 23422 3 2727.209015 910.0775 Cytoplasmic polyadenylation element-binding protein 1 OS=Homo sapiens OX=9606 GN=CPEB1 PE=1 SV=1 4.13 3764.1 - 341759 - - - -0.6329 - 4.39 0.767 - 455.9 1 2 0 -0.0017 27 0 0 0 4.48E+06 3.79E+06 - - - 10.4942 0.9992 221125_WJC_METTL3_EV_vs_WT_F08.23436.23436.3 4.47E-07 14/76 K.HAASDVDLEIESLLNQQSTK[136.11].E "sp|Q86U44|MTA70_HUMAN,tr|F5H6D8|F5H6D8_HUMAN,tr|H0YFV6|H0YFV6_HUMAN,tr|B4DTN4|B4DTN4_HUMAN" 4 2205.1005 0.02 123498 23436 3 2206.099623 736.0408 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 4.31 3765.9 - 198378 - - - 453.1163 - 3.09 0.563 - 221.3 1 2 0 0.9992 20 0 0 0 1.10E+05 6.75E+06 - - - 7.2771 0.9999 221125_WJC_METTL3_EV_vs_WT_F08.23437.23437.4 4.44E-05 8/150 R.GSDPSTHQRPPSEMADFLSDAIPGLK.L "sp|Q8TC07|TBC15_HUMAN,tr|C9JA93|C9JA93_HUMAN" 2 2752.3126 0.82 123499 23437 4 2752.315078 689.0854 TBC1 domain family member 15 OS=Homo sapiens OX=9606 GN=TBC1D15 PE=1 SV=2 4.66 3766 - 136279 - - - 0.8843 - 1.669 0.434 - 30.3 1 2 0 0.0024 26 0 0 0 3.98E+06 4.83E+06 - - - 3.1644 1 221125_WJC_METTL3_EV_vs_WT_F08.23440.23440.4 1.20E-06 18/120 R.K[136.11]HAASDVDLEIESLLNQQSTK[136.11].E "sp|Q86U44|MTA70_HUMAN,tr|F5H6D8|F5H6D8_HUMAN,tr|H0YFV6|H0YFV6_HUMAN,tr|B4DTN4|B4DTN4_HUMAN" 4 2341.2096 0.02 123500 23440 4 2341.212334 586.3097 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 4.75 3766.4 - 889502 - - - 1.1597 - 3.906 0.506 - 252.7 1 2 0 0.0027 21 0 0 0 4.27E+05 2.50E+07 - - - 4.08 0.9916 221125_WJC_METTL3_EV_vs_WT_F08.23445.23445.4 1.34E-05 11/156 K.NK[136.11]SEDSTK[136.11]DDIDLDALAAEIEGAGAAK[136.11].E "sp|O60841|IF2P_HUMAN,tr|A0A087WUT6|A0A087WUT6_HUMAN" 2 2770.3571 0.57 123503 23445 4 2770.355363 693.5965 Eukaryotic translation initiation factor 5B OS=Homo sapiens OX=9606 GN=EIF5B PE=1 SV=4 4.03 3767.1 - 267701 - - - -0.6191 - 2.073 0.263 - 44.3 1 2 2 -0.0017 27 0 0 0 6.33E+06 1.11E+07 - - - 1.7428 1 221125_WJC_METTL3_EV_vs_WT_F08.23458.23458.4 6.25E-08 18/156 K.NKSEDSTKDDIDLDALAAEIEGAGAAK.E "sp|O60841|IF2P_HUMAN,tr|A0A087WUT6|A0A087WUT6_HUMAN" 2 2746.3145 0.57 123510 23458 4 2746.323705 687.5859 Eukaryotic translation initiation factor 5B OS=Homo sapiens OX=9606 GN=EIF5B PE=1 SV=4 4.03 3769 - 263442 - - - 3.3598 - 3.149 0.635 - 274.8 1 2 2 0.0092 27 0 0 0 6.21E+06 1.09E+07 - - - 5.1094 1 221125_WJC_METTL3_EV_vs_WT_F08.23462.23462.4 7.77E-12 16/192 R.KREDAITQQNTIQNEAVNLLDPGSSYLLQEPPR.T "sp|Q96IZ0|PAWR_HUMAN,tr|H0YI16|H0YI16_HUMAN" 2 3736.902 0.82 123512 23462 4 3736.909455 935.2328 PRKC apoptosis WT1 regulator protein OS=Homo sapiens OX=9606 GN=PAWR PE=1 SV=1 4.51 3769.5 - 133746 - - - 1.9867 - 4.051 0.677 - 112.7 1 2 1 0.0074 33 0 0 0 2.97E+06 3.62E+06 - - - 5.5363 0.9999 221125_WJC_METTL3_EV_vs_WT_F08.23467.23467.4 8.96E-08 16/192 R.K[136.11]R[166.11]EDAITQQNTIQNEAVNLLDPGSSYLLQEPPR[166.11].T "sp|Q96IZ0|PAWR_HUMAN,tr|H0YI16|H0YI16_HUMAN" 2 3764.9328 0.83 123515 23467 4 3764.935102 942.2405 PRKC apoptosis WT1 regulator protein OS=Homo sapiens OX=9606 GN=PAWR PE=1 SV=1 4.51 3770.2 - 162332 - - - 0.6191 - 3.495 0.597 - 100.1 1 2 1 0.0023 33 0 0 0 2.97E+06 3.58E+06 - - - 4.7971 0.9999 221125_WJC_METTL3_EV_vs_WT_F08.23473.23473.3 6.19E-06 Jul-52 K.K[136.11]GPGEVAGTVTGQK[136.11].R "sp|Q86U44|MTA70_HUMAN,tr|F5H6D8|F5H6D8_HUMAN,tr|H0YFV6|H0YFV6_HUMAN,tr|B4DTN4|B4DTN4_HUMAN" 4 1343.738 0.001 123519 23473 3 1343.739647 448.9199 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 8.59 3771.1 - 71003.5 - - - 1.2413 - 1.537 0.517 - 44.6 1 2 0 0.0017 14 0 0 0 0.00E+00 3.37E+06 - - - 5.4459 1 221125_WJC_METTL3_EV_vs_WT_F08.23479.23479.4 1.43E-09 13/138 K.LNDFRDEQIGQLQELMQEATKPNR.Q sp|Q9NRP4|SDHF3_HUMAN 1 2872.4138 1.85 123523 23479 4 2872.428403 719.1107 "Succinate dehydrogenase assembly factor 3, mitochondrial OS=Homo sapiens OX=9606 GN=SDHAF3 PE=1 SV=1" 4.51 3771.9 - 74945.8 - - - 5.0995 - 3.119 0.646 - 112.2 1 2 1 0.0146 24 0 0 0 1.60E+06 8.65E+05 - - - 5.2098 0.9977 221125_WJC_METTL3_EV_vs_WT_F08.23485.23485.3 0.00349 Sep-76 K.KDELDSLITAITTNGAHPSK.C "sp|Q13485|SMAD4_HUMAN,tr|K7EIU8|K7EIU8_HUMAN,tr|K7EL18|K7EL18_HUMAN,tr|K7ENG1|K7ENG1_HUMAN,tr|K7EL15|K7EL15_HUMAN,tr|K7EIJ2|K7EIJ2_HUMAN,tr|K7ES96|K7ES96_HUMAN" 7 2110.0906 3.65 123527 23485 3 2110.098273 704.3708 Mothers against decapentaplegic homolog 4 OS=Homo sapiens OX=9606 GN=SMAD4 PE=1 SV=1 5.38 3772.7 - 139118 - - - 3.6302 - 2.482 0.297 - 100.5 1 2 0 0.0077 20 0 0 0 3.79E+06 1.04E+06 - - - 4.0545 0.9999 221125_WJC_METTL3_EV_vs_WT_F08.23487.23487.3 0.00239 Jun-68 R.IGPYQPNVPVGIDYVIPK.T "sp|P43243|MATR3_HUMAN,tr|B3KM87|B3KM87_HUMAN,tr|A8MXP9|A8MXP9_HUMAN,tr|A0A0R4J2E8|A0A0R4J2E8_HUMAN" 4 1968.072 1.61 123529 23487 3 1968.075101 657.0313 Matrin-3 OS=Homo sapiens OX=9606 GN=MATR3 PE=1 SV=2 5.83 3772.9 - 134249 - - - 1.5502 - 1.62 0.506 - 32.9 1 2 0 0.0031 18 0 0 0 5.44E+06 3.38E+06 - - - 5.3818 1 221125_WJC_METTL3_EV_vs_WT_F08.23493.23493.4 3.14E-05 9/114 K.KDELDSLITAITTNGAHPSK.C "sp|Q13485|SMAD4_HUMAN,tr|K7EIU8|K7EIU8_HUMAN,tr|K7EL18|K7EL18_HUMAN,tr|K7ENG1|K7ENG1_HUMAN,tr|K7EL15|K7EL15_HUMAN,tr|K7EIJ2|K7EIJ2_HUMAN,tr|K7ES96|K7ES96_HUMAN" 7 2110.0906 1.49 123533 23493 4 2110.092396 528.5299 Mothers against decapentaplegic homolog 4 OS=Homo sapiens OX=9606 GN=SMAD4 PE=1 SV=1 5.38 3773.8 - 112762 - - - 0.845 - 2.119 0.503 - 39.3 1 2 0 0.0018 20 0 0 0 1.44E+06 9.66E+05 - - - 3.8547 0.9574 221125_WJC_METTL3_EV_vs_WT_F08.23496.23496.4 0.00549 7/204 K.QSKPVTTPEEIAQVATISANGDKEIGNIISDAMK[136.11]K[136.11].V "sp|P10809|CH60_HUMAN,tr|A0A7I2V599|A0A7I2V599_HUMAN,tr|E7EXB4|E7EXB4_HUMAN,tr|A0A7I2YQ71|A0A7I2YQ71_HUMAN,tr|E7ESH4|E7ESH4_HUMAN,tr|A0A7I2V5M1|A0A7I2V5M1_HUMAN,tr|A0A7I2V5K3|A0A7I2V5K3_HUMAN,tr|A0A7I2V369|A0A7I2V369_HUMAN" 8 3698.9372 - 123536 23496 4 3698.918916 925.7416 "60 kDa heat shock protein, mitochondrial OS=Homo sapiens OX=9606 GN=HSPD1 PE=1 SV=2" 4.94 3774.2 - 119838 - - - -4.9311 - 2.188 0.304 - 16.9 1 2 1 -0.0182 35 0 0 0 - - - - - 2.0991 1 221125_WJC_METTL3_EV_vs_WT_F08.23500.23500.3 1.96E-08 17/80 R.K[136.11]HAASDVDLEIESLLNQQSTK[136.11].E "sp|Q86U44|MTA70_HUMAN,tr|F5H6D8|F5H6D8_HUMAN,tr|H0YFV6|H0YFV6_HUMAN,tr|B4DTN4|B4DTN4_HUMAN" 4 2341.2096 0.32 123538 23500 3 2341.209685 781.4105 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 4.75 3774.7 - 342510 - - - 0.0282 - 3.37 0.595 - 187.7 1 2 0 0.0001 21 0 0 0 6.01E+06 1.88E+07 - - - 8.0863 1 221125_WJC_METTL3_EV_vs_WT_F08.23501.23501.3 3.19E-08 13/80 K.RIDTPSLEEPSDLEELEQFAK.T "sp|P14859|PO2F1_HUMAN,tr|A0A0C4DG88|A0A0C4DG88_HUMAN" 2 2445.1911 2.14 123539 23501 3 2445.203854 816.071 "POU domain, class 2, transcription factor 1 OS=Homo sapiens OX=9606 GN=POU2F1 PE=1 SV=2" 4 3774.9 - 135640 - - - 5.2098 - 3.04 0.669 - 199.4 1 2 0 0.0127 21 0 0 0 1.49E+06 6.94E+05 - - - 8.6608 0.8501 221125_WJC_METTL3_EV_vs_WT_F08.23507.23507.3 0.00265 14/64 R.K[136.11]HAASDVDLEIESLLNQ.Q "sp|Q86U44|MTA70_HUMAN,tr|F5H6D8|F5H6D8_HUMAN,tr|H0YFV6|H0YFV6_HUMAN,tr|B4DTN4|B4DTN4_HUMAN" 4 1888.9622 0.02 123543 23507 3 1888.971409 630.6613 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 4.31 3775.7 - 231135 - - - 4.89 - 2.389 0.392 - 294.6 1 1 0 0.0092 17 0 0 0 3.66E+04 2.07E+06 - - - 5.1079 0.9994 221125_WJC_METTL3_EV_vs_WT_F08.23508.23508.2 0.000467 Aug-34 R.IGPYQPNVPVGIDYVIPK.T "sp|P43243|MATR3_HUMAN,tr|B3KM87|B3KM87_HUMAN,tr|A8MXP9|A8MXP9_HUMAN,tr|A0A0R4J2E8|A0A0R4J2E8_HUMAN" 4 1968.072 1.71 123544 23508 2 1968.074896 985.0433 Matrin-3 OS=Homo sapiens OX=9606 GN=MATR3 PE=1 SV=2 5.83 3775.8 - 136227 - - - 1.4461 - 1.622 0.436 - 124.5 1 2 0 0.0028 18 0 0 0 3.77E+06 2.20E+06 - - - 3.4495 0.9999 221125_WJC_METTL3_EV_vs_WT_F08.23513.23513.3 4.46E-06 9/128 R.SDSPVPTAPTSGGPK[136.11]PSTASAVPELATDPELEK[136.11].K "sp|Q86U44|MTA70_HUMAN,tr|B4E349|B4E349_HUMAN,tr|F5H6D8|F5H6D8_HUMAN,tr|B4DTN4|B4DTN4_HUMAN" 4 3248.6271 0.001 123547 23513 3 3248.632391 1083.883 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 4.18 3776.5 - 160480 - - - 1.6293 - 2.014 0.525 - 36.5 1 2 0 0.0053 33 0 0 0 0.00E+00 2.79E+06 - - - 6.0025 1 221125_WJC_METTL3_EV_vs_WT_F08.23523.23523.3 7.64E-07 12/112 R.R[166.11]AEQDSTTVAAFASSLVSGLNSSASEPAK[136.11].E "sp|Q86U44|MTA70_HUMAN,tr|F5H6D8|F5H6D8_HUMAN,tr|H0YFV6|H0YFV6_HUMAN,tr|B4DTN4|B4DTN4_HUMAN" 4 2898.4326 0.001 123554 23523 3 2898.432675 967.1515 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 4.68 3777.8 - 109843 - - - 0.0328 - 2.656 0.575 - 114.7 1 2 0 0.0001 29 0 0 0 0.00E+00 1.64E+06 - - - 7.198 1 221125_WJC_METTL3_EV_vs_WT_F08.23529.23529.3 2.15E-09 13/104 R.ALYDAELSQMQTHISDTSVVLSMDNNR.N "sp|P48668|K2C6C_HUMAN,sp|P04259|K2C6B_HUMAN,sp|P02538|K2C6A_HUMAN" 3 3037.4121 999 123558 23529 3 3037.422736 1013.478 "Keratin, type II cytoskeletal 6C OS=Homo sapiens OX=9606 GN=KRT6C PE=1 SV=3" 4.22 3778.7 - 103317 - - - 3.5017 - 2.926 0.683 - 154.2 1 2 0 0.0106 27 0 0 0 2.42E+06 0.00E+00 - - - 8.6219 0.9926 221125_WJC_METTL3_EV_vs_WT_F08.23534.23534.2 0.00232 22-Jun K.ADTLTDEINFLR.A "sp|P48668|K2C6C_HUMAN,sp|P04259|K2C6B_HUMAN,sp|P02538|K2C6A_HUMAN" 3 1406.7042 5.67 123561 23534 2 1406.708048 704.3594 "Keratin, type II cytoskeletal 6C OS=Homo sapiens OX=9606 GN=KRT6C PE=1 SV=3" 4.03 3779.4 - 65009.2 - - - 2.7646 - 1.531 0.225 - 127.3 1 2 0 0.0039 12 0 0 0 8.66E+06 1.53E+06 - - - 1.8223 0.9824 221125_WJC_METTL3_EV_vs_WT_F08.23542.23542.3 0.00429 Jun-68 R.IGPYQPNVPVGIDYVIPK[136.11].T "sp|P43243|MATR3_HUMAN,tr|B3KM87|B3KM87_HUMAN,tr|A8MXP9|A8MXP9_HUMAN,tr|A0A0R4J2E8|A0A0R4J2E8_HUMAN" 4 1976.0863 1.62 123565 23542 3 1976.094352 659.7027 Matrin-3 OS=Homo sapiens OX=9606 GN=MATR3 PE=1 SV=2 5.83 3780.5 - 110566 - - - 4.1 - 1.336 0.318 - 34.4 1 2 0 0.0081 18 0 0 0 5.48E+06 3.38E+06 - - - 2.8045 0.9999 221125_WJC_METTL3_EV_vs_WT_F08.23546.23546.3 6.87E-06 Oct-56 R.STSHK[136.11]PDEIYGMIER[166.11].L sp|Q86U44|MTA70_HUMAN 1 1779.8581 0.02 123567 23546 3 1779.862077 594.2933 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 5.42 3781.1 - 132076 - - - 2.2603 - 1.869 0.552 - 108.6 1 2 0 0.004 15 0 0 0 9.46E+04 5.66E+06 - - - 6.325 0.9997 221125_WJC_METTL3_EV_vs_WT_F08.23559.23559.4 1.46E-06 16/162 R.QNLDTIVQAIQHIEGTQEKQELEEEQRR.A sp|Q01664|TFAP4_HUMAN 1 3361.6862 1.41 123575 23559 4 3361.691635 841.4288 Transcription factor AP-4 OS=Homo sapiens OX=9606 GN=TFAP4 PE=1 SV=2 4.54 3783.1 - 508993 - - - 1.6093 - 3.033 0.447 - 145.3 1 2 1 0.0054 28 0 0 0 1.14E+07 8.07E+06 - - - 3.4597 1 221125_WJC_METTL3_EV_vs_WT_F08.23583.23583.3 5.54E-09 11/104 K.VLYDAEISQIHQSVTDTNVILSMDNSR.N sp|P35908|K22E_HUMAN 1 3047.487 999 123589 23583 3 3047.496167 1016.8363 "Keratin, type II cytoskeletal 2 epidermal OS=Homo sapiens OX=9606 GN=KRT2 PE=1 SV=2" 4.22 3786.4 - 129182 - - - 3.0146 - 3.12 0.653 - 94.6 1 2 0 0.0092 27 0 0 0 5.39E+06 0.00E+00 - - - 8.4355 0.9999 221125_WJC_METTL3_EV_vs_WT_F08.23597.23597.4 6.21E-05 7/156 K.VLYDAEISQIHQSVTDTNVILSMDNSR.N sp|P35908|K22E_HUMAN 1 3047.487 16.05 123597 23597 4 3047.49581 762.879 "Keratin, type II cytoskeletal 2 epidermal OS=Homo sapiens OX=9606 GN=KRT2 PE=1 SV=2" 4.22 3788.4 - 191948 - - - 2.8975 - 1.947 0.52 - 22.4 1 2 0 0.0088 27 0 0 0 4.34E+06 2.70E+05 - - - 3.9581 1 221125_WJC_METTL3_EV_vs_WT_F08.23598.23598.4 5.37E-07 14/252 K.ALANVNIGSLIC[160.03]NVGAGGPAPAAGAAPAGGPAPSTAAAPAEEK.K sp|P05386|RLA1_HUMAN 1 3807.9214 1.67 123598 23598 4 3807.928636 952.9876 60S acidic ribosomal protein P1 OS=Homo sapiens OX=9606 GN=RPLP1 PE=1 SV=1 4.53 3788.5 - 150397 - - - 1.9037 - 2.856 0.532 - 60.6 1 2 0 0.0072 43 0 0 0 4.93E+07 2.95E+07 - - - 4.1532 0.9999 221125_WJC_METTL3_EV_vs_WT_F08.23604.23604.3 1.50E-06 7/120 R.SSGGSGGGPLSHFYSGSPTSYFTSGLQAGLK[136.11].Q "tr|K7EQG2|K7EQG2_HUMAN,tr|E9PAU2|E9PAU2_HUMAN,tr|A0A087WZ13|A0A087WZ13_HUMAN" 3 2998.4188 0.75 123602 23604 3 2998.42508 1000.4802 Uncharacterized protein (Fragment) OS=Homo sapiens OX=9606 PE=1 SV=1 8.24 3789.3 - 69056.8 - - - 2.0844 - 1.736 0.604 - 35.1 1 2 0 0.0062 31 0 0 0 1.85E+06 2.46E+06 - - - 6.5413 0.9876 221125_WJC_METTL3_EV_vs_WT_F08.23605.23605.2 0.224 28-May R.NIETIINTFHQYSVK.L sp|P06702|S10A9_HUMAN 1 1805.9312 999 123603 23605 2 1805.927966 903.9729 Protein S100-A9 OS=Homo sapiens OX=9606 GN=S100A9 PE=1 SV=1 6.75 3789.5 - 44874.3 - - - -1.7902 - 1.097 0.221 - 55.5 1 2 0 -0.0032 15 0 0 0 1.11E+06 0.00E+00 - - - 0.8999 1 221125_WJC_METTL3_EV_vs_WT_F08.23610.23610.3 1.68E-08 15/168 K.ALANVNIGSLIC[160.03]NVGAGGPAPAAGAAPAGGPAPSTAAAPAEEK.K sp|P05386|RLA1_HUMAN 1 3807.9214 2.26 123605 23610 3 3807.929431 1270.3144 60S acidic ribosomal protein P1 OS=Homo sapiens OX=9606 GN=RPLP1 PE=1 SV=1 4.53 3790.2 - 133595 - - - 2.1124 - 2.898 0.612 - 79.6 1 2 0 0.008 43 0 0 0 1.71E+07 7.55E+06 - - - 7.8089 0.9999 221125_WJC_METTL3_EV_vs_WT_F08.23611.23611.3 4.00E-10 13/72 K.NKLNDLEDALQQAKEDLAR.L sp|P04264|K2C1_HUMAN 1 2183.1182 229.07 123606 23611 3 2183.123801 728.7134 "Keratin, type II cytoskeletal 1 OS=Homo sapiens OX=9606 GN=KRT1 PE=1 SV=6" 4.44 3790.4 - 68535.4 - - - 2.5541 - 2.977 0.615 - 159.7 1 2 2 0.0056 19 0 0 0 4.14E+07 1.81E+05 - - - 8.0753 1 221125_WJC_METTL3_EV_vs_WT_F08.23615.23615.4 5.85E-07 12/270 K.EPSAAAPTGAGGVAPGSGNNSGGPSLLVPLPVNPPSSPTPSFSDAK.A "sp|O75175|CNOT3_HUMAN,tr|B7Z6J7|B7Z6J7_HUMAN,tr|A0A2H2FJL5|A0A2H2FJL5_HUMAN,tr|H7C3F5|H7C3F5_HUMAN,tr|A0A2R8Y4W0|A0A2R8Y4W0_HUMAN,tr|H0Y5X7|H0Y5X7_HUMAN" 6 4210.0818 2.42 123607 23615 4 4210.078484 1053.5277 CCR4-NOT transcription complex subunit 3 OS=Homo sapiens OX=9606 GN=CNOT3 PE=1 SV=1 4.37 3791 - 83591.1 - - - -0.7986 - 2.479 0.631 - 44 1 2 0 -0.0034 46 0 0 0 1.91E+07 7.89E+06 - - - 4.9723 0.9987 221125_WJC_METTL3_EV_vs_WT_F08.23621.23621.2 3.72E-05 22-Aug R.LFPPQWIC[160.03]C[160.03]DIR[166.11].Y sp|Q86U44|MTA70_HUMAN 1 1613.7722 0 123610 23621 2 1613.778755 807.8934 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 5.82 3791.8 - 203739 - - - 4.0557 - 1.879 0.545 - 166.7 1 2 0 0.0065 12 0 0 0 3.58E+04 1.34E+07 - - - 4.7239 1 221125_WJC_METTL3_EV_vs_WT_F08.23622.23622.4 6.88E-09 15/252 R.APAQNPELTPGPAPAGPTPAPETNAPNHPSPAEYVEVLQELQR.L "sp|P46379|BAG6_HUMAN,tr|A0A7I2V508|A0A7I2V508_HUMAN,tr|A0A0G2JJM1|A0A0G2JJM1_HUMAN,tr|X6REW1|X6REW1_HUMAN,tr|A0A7P0MQS5|A0A7P0MQS5_HUMAN,tr|F6S6P2|F6S6P2_HUMAN,tr|A0A0G2JL47|A0A0G2JL47_HUMAN,tr|A0A024RCR6|A0A024RCR6_HUMAN,tr|A0A0G2JK23|A0A0G2JK23_HUMAN" 9 4452.1986 2.47 123611 23622 4 4452.202734 1114.0569 Large proline-rich protein BAG6 OS=Homo sapiens OX=9606 GN=BAG6 PE=1 SV=2 4.32 3791.9 - 156003 - - - 0.9267 - 3.4 0.478 - 45.5 1 2 0 0.0041 43 0 0 0 3.09E+07 1.25E+07 - - - 3.7337 0.9999 221125_WJC_METTL3_EV_vs_WT_F08.23631.23631.4 4.81E-08 17/108 K.NKLNDLEDALQQAKEDLAR.L sp|P04264|K2C1_HUMAN 1 2183.1182 152.22 123614 23631 4 2183.121885 546.7868 "Keratin, type II cytoskeletal 1 OS=Homo sapiens OX=9606 GN=KRT1 PE=1 SV=6" 4.44 3793.3 - 274815 - - - 1.6765 - 3.404 0.532 - 208.9 1 2 2 0.0037 19 0 0 0 1.79E+07 1.18E+05 - - - 4.2699 0.9998 221125_WJC_METTL3_EV_vs_WT_F08.23654.23654.3 0.0023 Jul-76 K.HAASDVDLEIESLLNQQSTK[136.11].E "sp|Q86U44|MTA70_HUMAN,tr|F5H6D8|F5H6D8_HUMAN,tr|H0YFV6|H0YFV6_HUMAN,tr|B4DTN4|B4DTN4_HUMAN" 4 2205.1005 0.06 123626 23654 3 2205.101116 736.0408 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 4.31 3796.5 - 112668 - - - 0.2993 - 1.474 0.475 - 42.7 1 2 0 0.0007 20 0 0 0 3.10E+05 4.94E+06 - - - 4.7768 0.9974 221125_WJC_METTL3_EV_vs_WT_F08.23658.23658.3 1.05E-07 16/128 R.AEQDSTTVAAFASSLVSGLNSSASEPAK[136.11]EPAK[136.11]K[136.11].S "sp|Q86U44|MTA70_HUMAN,tr|F5H6D8|F5H6D8_HUMAN,tr|H0YFV6|H0YFV6_HUMAN,tr|B4DTN4|B4DTN4_HUMAN" 4 3301.674 0.001 123627 23658 3 3302.6734 1101.5653 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 4.87 3797.1 - 241221 - - - 302.6965 - 2.96 0.583 - 162.7 1 2 1 0.9994 33 0 0 0 0.00E+00 8.32E+06 - - - 7.2597 0.9997 221125_WJC_METTL3_EV_vs_WT_F08.23659.23659.4 9.57E-05 8/156 R.IRSEDEEDLGNARPSAPSTLFDFLESK.M sp|Q9H7E2|TDRD3_HUMAN 1 3022.452 0.41 123628 23659 4 3022.458222 756.6203 Tudor domain-containing protein 3 OS=Homo sapiens OX=9606 GN=TDRD3 PE=1 SV=1 4.2 3797.3 - 60784.9 - - - 2.0672 - 1.736 0.496 - 32.3 1 2 1 0.0062 27 0 0 0 7.51E+05 1.82E+06 - - - 3.714 0.9892 221125_WJC_METTL3_EV_vs_WT_F08.23672.23672.3 0.00371 7/168 K.ALANVNIGSLIC[160.03]NVGAGGPAPAAGAAPAGGPAPSTAAAPAEEK[136.11].K sp|P05386|RLA1_HUMAN 1 3815.9356 2.26 123632 23672 3 3816.93598 1272.9858 60S acidic ribosomal protein P1 OS=Homo sapiens OX=9606 GN=RPLP1 PE=1 SV=1 4.53 3799.3 - 92144.6 - - - 262.1619 - 1.415 0.441 - 20.3 1 2 0 1.0004 43 0 0 0 1.71E+07 7.55E+06 - - - 3.9782 0.9362 221125_WJC_METTL3_EV_vs_WT_F08.23676.23676.2 2.6 16-Apr K.DAEDWFFSK.T "sp|Q04695|K1C17_HUMAN,tr|K7ESE1|K7ESE1_HUMAN,tr|F5GWP8|F5GWP8_HUMAN" 3 1143.4873 24.52 123636 23676 2 1143.486102 572.7509 "Keratin, type I cytoskeletal 17 OS=Homo sapiens OX=9606 GN=KRT17 PE=1 SV=2" 4.03 3799.8 - 84115.6 - - - -1.0389 - 0.79 0.158 - 65 1 2 0 -0.0012 9 0 0 0 2.04E+06 8.30E+04 - - - -0.4743 0.995 221125_WJC_METTL3_EV_vs_WT_F08.23684.23684.4 0.00059 11/252 K.ALANVNIGSLIC[160.03]NVGAGGPAPAAGAAPAGGPAPSTAAAPAEEK[136.11].K sp|P05386|RLA1_HUMAN 1 3815.9356 1.67 123641 23684 4 3816.929943 954.9912 60S acidic ribosomal protein P1 OS=Homo sapiens OX=9606 GN=RPLP1 PE=1 SV=1 4.53 3800.9 - 110560 - - - 260.5799 - 2.449 0.472 - 31.4 1 2 0 0.9944 43 0 0 0 4.93E+07 2.95E+07 - - - 3.3138 0.9992 221125_WJC_METTL3_EV_vs_WT_F08.23687.23687.3 0.00302 Jun-52 K.K[136.11]GPGEVAGTVTGQK[136.11].R "sp|Q86U44|MTA70_HUMAN,tr|F5H6D8|F5H6D8_HUMAN,tr|H0YFV6|H0YFV6_HUMAN,tr|B4DTN4|B4DTN4_HUMAN" 4 1343.738 0 123643 23687 3 1343.738116 448.9199 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 8.59 3801.3 - 81018.2 - - - 0.102 - 1.417 0.357 - 48.3 1 2 0 0.0001 14 0 0 0 1.37E+04 8.02E+06 - - - 3.4464 1 221125_WJC_METTL3_EV_vs_WT_F08.23712.23712.3 1.76E-07 22/80 R.K[136.11]HAASDVDLEIESLLNQQSTK[136.11].E "sp|Q86U44|MTA70_HUMAN,tr|F5H6D8|F5H6D8_HUMAN,tr|H0YFV6|H0YFV6_HUMAN,tr|B4DTN4|B4DTN4_HUMAN" 4 2341.2096 0.09 123651 23712 3 2341.206246 781.4105 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 4.75 3805.1 - 325930 - - - -1.4407 - 3.774 0.59 - 662.4 1 2 0 -0.0034 21 0 0 0 5.42E+06 5.77E+07 - - - 8.3011 1 221125_WJC_METTL3_EV_vs_WT_F08.23714.23714.4 7.83E-07 17/120 R.K[136.11]HAASDVDLEIESLLNQQSTK[136.11].E "sp|Q86U44|MTA70_HUMAN,tr|F5H6D8|F5H6D8_HUMAN,tr|H0YFV6|H0YFV6_HUMAN,tr|B4DTN4|B4DTN4_HUMAN" 4 2341.2096 0.01 123653 23714 4 2341.21016 586.3097 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 4.75 3805.4 - 563221 - - - 0.2311 - 3.736 0.509 - 232.2 1 2 0 0.0005 21 0 0 0 5.92E+05 6.48E+07 - - - 4.092 1 221125_WJC_METTL3_EV_vs_WT_F08.23729.23729.3 1.56E-05 Jul-56 R.HFYWYLTNEGIQYLR.D "sp|P46783|RS10_HUMAN,tr|A0A2R8Y6L3|A0A2R8Y6L3_HUMAN,tr|F6U211|F6U211_HUMAN,tr|A0A1W2PQS6|A0A1W2PQS6_HUMAN,tr|A0A2R8YFH6|A0A2R8YFH6_HUMAN,tr|A0A2R8Y7H1|A0A2R8Y7H1_HUMAN,tr|S4R435|S4R435_HUMAN" 7 2001.9737 1.1 123661 23729 3 2001.975078 668.3319 40S ribosomal protein S10 OS=Homo sapiens OX=9606 GN=RPS10 PE=1 SV=1 6.75 3807.5 - 44984.7 - - - 0.6718 - 1.746 0.533 - 76.1 1 2 0 0.0013 15 0 0 0 6.56E+06 5.96E+06 - - - 5.9363 0.9995 221125_WJC_METTL3_EV_vs_WT_F08.23736.23736.2 0.000102 13/28 K.VSQEILELLNTTTAK[136.11].E "sp|Q86U44|MTA70_HUMAN,tr|H0YFV6|H0YFV6_HUMAN" 2 1666.9233 0.02 123666 23736 2 1666.928378 834.4689 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 4.53 3808.5 - 93051.3 - - - 3.0661 - 2.766 0.495 - 630.6 1 2 0 0.0051 15 0 0 0 2.73E+06 1.65E+08 - - - 5.1968 1 221125_WJC_METTL3_EV_vs_WT_F08.23745.23745.4 3.58E-12 21/174 K.KSEAAVPPWVDTNDEETIQQQILALSADKR.N sp|Q96A49|SYAP1_HUMAN 1 3351.6947 1.32 123671 23745 4 3351.703193 838.9309 Synapse-associated protein 1 OS=Homo sapiens OX=9606 GN=SYAP1 PE=1 SV=1 4.3 3809.7 - 260540 - - - 2.5447 - 3.7 0.695 - 196.1 1 2 0 0.0085 30 0 0 0 1.68E+08 1.27E+08 - - - 5.6733 1 221125_WJC_METTL3_EV_vs_WT_F08.23761.23761.3 6.58E-09 Dec-56 R.HFYWYLTNEGIQYLR[166.11].D "sp|P46783|RS10_HUMAN,tr|A0A2R8Y6L3|A0A2R8Y6L3_HUMAN,tr|F6U211|F6U211_HUMAN,tr|A0A1W2PQS6|A0A1W2PQS6_HUMAN,tr|A0A2R8YFH6|A0A2R8YFH6_HUMAN,tr|A0A2R8Y7H1|A0A2R8Y7H1_HUMAN,tr|S4R435|S4R435_HUMAN" 7 2011.982 1.1 123679 23761 3 2011.981985 671.6679 40S ribosomal protein S10 OS=Homo sapiens OX=9606 GN=RPS10 PE=1 SV=1 6.75 3811.8 - 282077 - - - -0.0089 - 2.572 0.601 - 271.3 1 2 0 0 15 0 0 0 6.56E+06 5.96E+06 - - - 7.7056 1 221125_WJC_METTL3_EV_vs_WT_F08.23775.23775.3 1.12E-06 12/116 K.K[136.11]SEAAVPPWVDTNDEETIQQQILALSADK[136.11]R[166.11].N sp|Q96A49|SYAP1_HUMAN 1 3377.7313 1.72 123685 23775 3 3377.731602 1126.9177 Synapse-associated protein 1 OS=Homo sapiens OX=9606 GN=SYAP1 PE=1 SV=1 4.3 3813.8 - 83183 - - - 0.0793 - 1.95 0.567 - 92.8 1 2 0 0.0003 30 0 0 0 6.75E+06 3.93E+06 - - - 6.3978 0.9307 221125_WJC_METTL3_EV_vs_WT_F08.23776.23776.2 2.64E-05 28-Oct K.VSQEILELLNTTTAK.E "sp|Q86U44|MTA70_HUMAN,tr|H0YFV6|H0YFV6_HUMAN" 2 1658.9091 0.02 123686 23776 2 1659.906611 830.4618 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 4.53 3813.9 - 52631 - - - 601.3253 - 2.238 0.399 - 273.2 1 2 0 0.9975 15 0 0 0 2.73E+06 1.65E+08 - - - 3.6553 0.9877 221125_WJC_METTL3_EV_vs_WT_F08.23783.23783.3 0.192 Jun-56 R.STSHK[136.11]PDEIYGMIER[166.11].L sp|Q86U44|MTA70_HUMAN 1 1779.8581 0.15 123688 23783 3 1779.855372 594.2933 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 5.42 3814.9 - 157342 - - - -1.5069 - 1.293 0.236 - 38.4 1 2 0 -0.0027 15 0 0 0 9.92E+05 6.52E+06 - - - 1.8409 1 221125_WJC_METTL3_EV_vs_WT_F08.23790.23790.3 1.09E-08 15/56 K.VSQEILELLNTTTAK[136.11].E "sp|Q86U44|MTA70_HUMAN,tr|H0YFV6|H0YFV6_HUMAN" 2 1666.9233 0.02 123692 23790 3 1666.91887 556.6484 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 4.53 3815.7 - 9.80E+06 - - - -2.6378 - 2.839 0.571 - 382 1 2 0 -0.0044 15 0 0 0 5.06E+06 2.05E+08 - - - 7.6276 0.9997 221125_WJC_METTL3_EV_vs_WT_F08.23792.23792.2 7.82E-05 28-Sep K.VSQEILELLNTTTAK.E "sp|Q86U44|MTA70_HUMAN,tr|H0YFV6|H0YFV6_HUMAN" 2 1658.9091 0.02 123694 23792 2 1658.906615 830.4618 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 4.53 3815.9 - 115019 - - - -1.4781 - 1.914 0.466 - 227.3 1 2 0 -0.0025 15 0 0 0 2.73E+06 1.65E+08 - - - 4.0782 1 221125_WJC_METTL3_EV_vs_WT_F08.23803.23803.3 5.93E-07 14/116 K.KSEAAVPPWVDTNDEETIQQQILALSADKR.N sp|Q96A49|SYAP1_HUMAN 1 3351.6947 1.73 123698 23803 3 3351.68918 1118.2388 Synapse-associated protein 1 OS=Homo sapiens OX=9606 GN=SYAP1 PE=1 SV=1 4.3 3817.4 - 288351 - - - -1.6362 - 2.57 0.543 - 133.6 1 2 0 -0.0055 30 0 0 0 6.75E+06 3.91E+06 - - - 6.764 1 221125_WJC_METTL3_EV_vs_WT_F08.23810.23810.3 1.76E-09 12/120 K.INSSPNVNTTASGVEDLNIIQVTIPDDDNER.L "sp|P78347|GTF2I_HUMAN,tr|A0A494C1K3|A0A494C1K3_HUMAN" 2 3339.6066 2.39 123700 23810 3 3339.600378 1114.2095 General transcription factor II-I OS=Homo sapiens OX=9606 GN=GTF2I PE=1 SV=2 3.66 3818.5 - 136255 - - - -1.8742 - 2.525 0.659 - 72.1 1 2 0 -0.0063 31 0 0 0 7.33E+06 3.07E+06 - - - 8.0164 1 221125_WJC_METTL3_EV_vs_WT_F08.23819.23819.3 2.58E-08 Nov-64 K.LNDLEDALQQAKEDLAR.L sp|P04264|K2C1_HUMAN 1 1940.9803 999 123705 23819 3 1940.981316 648.0007 "Keratin, type II cytoskeletal 1 OS=Homo sapiens OX=9606 GN=KRT1 PE=1 SV=6" 4.11 3819.7 - 58526 - - - 0.5059 - 2.685 0.638 - 176.8 1 2 1 0.001 17 0 0 0 1.38E+06 0.00E+00 - - - 8.148 0.99 221125_WJC_METTL3_EV_vs_WT_F08.23822.23822.2 0.115 18-May K.FLLFGIQDGK.R "sp|P22105|TENX_HUMAN,tr|A0A140TA52|A0A140TA52_HUMAN,tr|A0A140T956|A0A140T956_HUMAN,tr|A0A140TA33|A0A140TA33_HUMAN,tr|A0A140T8Y3|A0A140T8Y3_HUMAN,tr|A0A3B3ISX9|A0A3B3ISX9_HUMAN,tr|A0A140T9C0|A0A140T9C0_HUMAN,tr|A0A140T902|A0A140T902_HUMAN,tr|A0A140T8Z8|A0A140T8Z8_HUMAN,tr|A0A140TA41|A0A140TA41_HUMAN" 10 1136.623 890.53 123706 23822 2 1136.622383 569.3188 Tenascin-X OS=Homo sapiens OX=9606 GN=TNXB PE=1 SV=5 5.84 3820 - 70474.1 - - - -0.5393 - 1.097 0.182 - 61.2 1 2 0 -0.0006 10 0 0 0 6.32E+06 7.10E+03 - - - 0.6435 0.9999 221125_WJC_METTL3_EV_vs_WT_F08.23829.23829.3 0.000266 7/128 R.SDSPVPTAPTSGGPK[136.11]PSTASAVPELATDPELEK[136.11].K "sp|Q86U44|MTA70_HUMAN,tr|B4E349|B4E349_HUMAN,tr|F5H6D8|F5H6D8_HUMAN,tr|B4DTN4|B4DTN4_HUMAN" 4 3248.6271 0.001 123708 23829 3 3248.630082 1083.883 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 4.18 3821 - 96242.3 - - - 0.9185 - 1.638 0.482 - 22.4 1 2 0 0.003 33 0 0 0 0.00E+00 1.00E+07 - - - 5.0483 0.9998 221125_WJC_METTL3_EV_vs_WT_F08.23843.23843.3 0.00193 7/120 R.TTPPEAAQNGQSPMAALILVADNAGGSHASK.D sp|Q7Z5L9|I2BP2_HUMAN 1 3003.472 1.79 123715 23843 3 3003.474842 1002.1646 Interferon regulatory factor 2-binding protein 2 OS=Homo sapiens OX=9606 GN=IRF2BP2 PE=1 SV=2 5.29 3823.1 - 69939.2 - - - 0.9469 - 1.711 0.43 - 35.1 1 2 0 0.0028 31 0 0 0 2.06E+06 1.15E+06 - - - 4.5689 1 221125_WJC_METTL3_EV_vs_WT_F08.23852.23852.4 2.61E-17 24/252 R.AQEEGPGEPPPPELALLPPPPPPPPTPATPTSSASNLDLGEQR.E "sp|Q7Z7K6|CENPV_HUMAN,tr|A0A0M3HER2|A0A0M3HER2_HUMAN" 2 4345.1754 2.13 123721 23852 4 4345.184664 1087.3011 Centromere protein V OS=Homo sapiens OX=9606 GN=CENPV PE=1 SV=1 3.83 3824.4 - 201082 - - - 2.1293 - 4.626 0.696 - 246.1 1 2 0 0.0093 43 0 0 0 8.06E+06 3.78E+06 - - - 5.7173 0.9973 221125_WJC_METTL3_EV_vs_WT_F08.23860.23860.3 0.0184 May-68 K.GPTEQLVSPEPEVYEILR.A "sp|O75688|PPM1B_HUMAN,tr|A0A3B3IS24|A0A3B3IS24_HUMAN,tr|C9JIR6|C9JIR6_HUMAN" 3 2055.0524 1.45 123724 23860 3 2055.058927 686.0248 Protein phosphatase 1B OS=Homo sapiens OX=9606 GN=PPM1B PE=1 SV=1 4.09 3825.6 - 77144.3 - - - 3.1581 - 1.375 0.387 - 21 1 2 0 0.0065 18 0 0 0 1.44E+06 9.88E+05 - - - 3.6458 0.9337 221125_WJC_METTL3_EV_vs_WT_F08.23862.23862.4 0.00126 7/174 Q.DSTTVAAFASSLVSGLNSSASEPAK[136.11]EPAK[136.11]K[136.11].S "sp|Q86U44|MTA70_HUMAN,tr|F5H6D8|F5H6D8_HUMAN,tr|H0YFV6|H0YFV6_HUMAN,tr|B4DTN4|B4DTN4_HUMAN" 4 2973.5357 0.05 123725 23862 4 2973.539279 744.3912 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 6.18 3825.8 - 101843 - - - 1.1999 - 1.808 0.409 - 18.8 1 1 1 0.0036 30 0 0 0 1.86E+05 3.52E+06 - - - 2.9662 0.9905 221125_WJC_METTL3_EV_vs_WT_F08.23881.23881.2 0.000487 22-Jun R.LFPPQWIC[160.03]C[160.03]DIR[166.11].Y sp|Q86U44|MTA70_HUMAN 1 1613.7722 0.001 123734 23881 2 1613.780378 807.8934 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 5.82 3828.6 - 97248.9 - - - 5.0614 - 1.373 0.437 - 99.5 1 2 0 0.0082 12 0 0 0 0.00E+00 6.27E+06 - - - 3.1002 1 221125_WJC_METTL3_EV_vs_WT_F08.23887.23887.4 1.15E-09 16/186 K.NQKDDVAQTDLLQIDPNFGSKEDFDSLLQSAK.K "sp|P08195|4F2_HUMAN,tr|A0A7P0TAN7|A0A7P0TAN7_HUMAN,tr|J3KPF3|J3KPF3_HUMAN,tr|F5H056|F5H056_HUMAN,tr|H0YH36|H0YH36_HUMAN,tr|A0A7P0TAT7|A0A7P0TAT7_HUMAN,tr|F5GZI0|F5GZI0_HUMAN,tr|A0A7P0T8U7|A0A7P0T8U7_HUMAN,tr|A0A7P0T9F7|A0A7P0T9F7_HUMAN,tr|A0A7P0TBF8|A0A7P0TBF8_HUMAN,tr|A0A7P0T8F1|A0A7P0T8F1_HUMAN,tr|A0A7P0Z4A0|A0A7P0Z4A0_HUMAN,tr|F5GZS6|F5GZS6_HUMAN,tr|A0A7P0Z4P5|A0A7P0Z4P5_HUMAN,tr|A0A7P0TAS6|A0A7P0TAS6_HUMAN" 15 3578.7377 1.43 123737 23887 4 3578.740415 895.6917 4F2 cell-surface antigen heavy chain OS=Homo sapiens OX=9606 GN=SLC3A2 PE=1 SV=3 4.04 3829.4 - 109019 - - - 0.7723 - 3.277 0.666 - 68.3 1 2 2 0.0028 32 0 0 0 3.37E+06 2.35E+06 - - - 5.3805 0.9989 221125_WJC_METTL3_EV_vs_WT_F08.23891.23891.2 0.00418 26-Jun K.LVINGNPITIFQER.D sp|P04406|G3P_HUMAN 1 1612.8937 1.11 123739 23891 2 1612.897364 807.4541 Glyceraldehyde-3-phosphate dehydrogenase OS=Homo sapiens OX=9606 GN=GAPDH PE=1 SV=3 6 3830 - 81970.7 - - - 2.2773 - 1.484 0.443 - 85 1 2 0 0.0037 14 0 0 0 2.75E+06 2.47E+06 - - - 3.3024 1 221125_WJC_METTL3_EV_vs_WT_F08.23897.23897.4 2.88E-08 15/186 K.NQK[136.11]DDVAQTDLLQIDPNFGSK[136.11]EDFDSLLQSAK[136.11].K "sp|P08195|4F2_HUMAN,tr|A0A7P0TAN7|A0A7P0TAN7_HUMAN,tr|J3KPF3|J3KPF3_HUMAN,tr|F5H056|F5H056_HUMAN,tr|H0YH36|H0YH36_HUMAN,tr|A0A7P0TAT7|A0A7P0TAT7_HUMAN,tr|F5GZI0|F5GZI0_HUMAN,tr|A0A7P0T8U7|A0A7P0T8U7_HUMAN,tr|A0A7P0T9F7|A0A7P0T9F7_HUMAN,tr|A0A7P0TBF8|A0A7P0TBF8_HUMAN,tr|A0A7P0T8F1|A0A7P0T8F1_HUMAN,tr|A0A7P0Z4A0|A0A7P0Z4A0_HUMAN,tr|F5GZS6|F5GZS6_HUMAN,tr|A0A7P0Z4P5|A0A7P0Z4P5_HUMAN,tr|A0A7P0TAS6|A0A7P0TAS6_HUMAN" 15 3602.7803 1.43 123743 23897 4 3602.781825 901.7023 4F2 cell-surface antigen heavy chain OS=Homo sapiens OX=9606 GN=SLC3A2 PE=1 SV=3 4.04 3830.8 - 131790 - - - 0.4369 - 3.249 0.633 - 72.1 1 2 2 0.0016 32 0 0 0 3.37E+06 2.35E+06 - - - 5.091 0.9998 221125_WJC_METTL3_EV_vs_WT_F08.23903.23903.2 3.09E-05 26-Aug K.LVINGNPITIFQER[166.11].D sp|P04406|G3P_HUMAN 1 1622.902 1.11 123747 23903 2 1622.900846 812.4583 Glyceraldehyde-3-phosphate dehydrogenase OS=Homo sapiens OX=9606 GN=GAPDH PE=1 SV=3 6 3831.6 - 84854.4 - - - -0.687 - 1.763 0.543 - 160.9 1 2 0 -0.0011 14 0 0 0 2.75E+06 2.47E+06 - - - 4.4741 1 221125_WJC_METTL3_EV_vs_WT_F08.23911.23911.4 3.74E-08 13/252 R.AQEEGPGEPPPPELALLPPPPPPPPTPATPTSSASNLDLGEQR[166.11].E "sp|Q7Z7K6|CENPV_HUMAN,tr|A0A0M3HER2|A0A0M3HER2_HUMAN" 2 4355.1837 2.12 123752 23911 4 4355.186156 1089.8032 Centromere protein V OS=Homo sapiens OX=9606 GN=CENPV PE=1 SV=1 3.83 3832.6 - 75062.2 - - - 0.5681 - 3.112 0.605 - 60.7 1 2 0 0.0025 43 0 0 0 8.03E+06 3.78E+06 - - - 4.8143 0.9999 221125_WJC_METTL3_EV_vs_WT_F08.23923.23923.4 2.22E-07 21/234 K.QKGDTPASATAPTEAAQIISAAGDTLSVPAPAVQPEESLK.T sp|Q16891|MIC60_HUMAN 1 3916.9906 1.45 123758 23923 4 3916.990982 980.2549 MICOS complex subunit MIC60 OS=Homo sapiens OX=9606 GN=IMMT PE=1 SV=1 4.18 3834.4 - 407377 - - - 0.1047 - 2.917 0.577 - 94.4 1 2 1 0.0004 40 0 0 0 5.93E+07 4.08E+07 - - - 4.5571 0.9999 221125_WJC_METTL3_EV_vs_WT_F08.23924.23924.4 0.000995 5/252 K.DLTVC[160.03]EPPKPQC[160.03]SLPQDPAIVQSSLGSSTSSFQSMGSYGPFGR.M "sp|Q8ND56|LS14A_HUMAN,tr|A0A140TA76|A0A140TA76_HUMAN,tr|K7EMZ9|K7EMZ9_HUMAN" 3 4599.1356 0.9 123759 23924 4 4599.144244 1150.7912 Protein LSM14 homolog A OS=Homo sapiens OX=9606 GN=LSM14A PE=1 SV=3 4.56 3834.5 - 91429.5 - - - 1.8762 - 1.396 0.49 - 7.2 1 2 0 0.0086 43 0 0 0 2.62E+06 2.92E+06 - - - 3.5835 0.9999 221125_WJC_METTL3_EV_vs_WT_F08.23935.23935.3 6.58E-08 13/156 K.QKGDTPASATAPTEAAQIISAAGDTLSVPAPAVQPEESLK.T sp|Q16891|MIC60_HUMAN 1 3916.9906 1.77 123765 23935 3 3916.990684 1306.6708 MICOS complex subunit MIC60 OS=Homo sapiens OX=9606 GN=IMMT PE=1 SV=1 4.18 3835.9 - 246151 - - - 0.0286 - 2.928 0.628 - 46.8 1 2 1 0.0001 40 0 0 0 1.87E+07 1.05E+07 - - - 8.0132 0.9999 221125_WJC_METTL3_EV_vs_WT_F08.23937.23937.3 2.39E-05 7/156 K.QK[136.11]GDTPASATAPTEAAQIISAAGDTLSVPAPAVQPEESLK[136.11].T sp|Q16891|MIC60_HUMAN 1 3933.019 1.77 123767 23937 3 3933.016248 1312.0136 MICOS complex subunit MIC60 OS=Homo sapiens OX=9606 GN=IMMT PE=1 SV=1 4.18 3836.2 - 133394 - - - -0.6926 - 2.236 0.539 - 14.8 1 2 1 -0.0027 40 0 0 0 1.87E+07 1.05E+07 - - - 6.3999 1 221125_WJC_METTL3_EV_vs_WT_F08.23951.23951.4 3.12E-09 13/174 K.K[136.11]SEAAVPPWVDTNDEETIQQQILALSADK[136.11]R[166.11].N sp|Q96A49|SYAP1_HUMAN 1 3377.7313 1.51 123775 23951 4 3377.73292 845.4401 Synapse-associated protein 1 OS=Homo sapiens OX=9606 GN=SYAP1 PE=1 SV=1 4.3 3838.1 - 166928 - - - 0.4695 - 2.562 0.653 - 62.9 1 2 0 0.0016 30 0 0 0 1.75E+07 1.15E+07 - - - 5.1972 1 221125_WJC_METTL3_EV_vs_WT_F08.23963.23963.4 0.000923 21/120 R.K[136.11]HAASDVDLEIESLLNQQSTK[136.11].E "sp|Q86U44|MTA70_HUMAN,tr|F5H6D8|F5H6D8_HUMAN,tr|H0YFV6|H0YFV6_HUMAN,tr|B4DTN4|B4DTN4_HUMAN" 4 2341.2096 0.01 123781 23963 4 2341.206512 586.3097 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 4.75 3839.8 - 719387 - - - -1.3271 - 4.056 0.508 - 336.2 1 2 0 -0.0031 21 0 0 0 1.68E+05 1.98E+07 - - - 4.1097 0.9992 221125_WJC_METTL3_EV_vs_WT_F08.23973.23973.3 0.0242 4/112 K.APLATGEDDDDEVPDLVENFDEASKNEAN.- "sp|P20290|BTF3_HUMAN,tr|A0A7I2V5Y3|A0A7I2V5Y3_HUMAN" 2 3118.3375 1.52 123787 23973 3 3118.342125 1040.4531 Transcription factor BTF3 OS=Homo sapiens OX=9606 GN=BTF3 PE=1 SV=1 3.42 3841.2 - 104153 - - - 1.4966 - 1.404 0.506 - 9.7 1 2 1 0.0047 29 0 0 0 2.79E+06 1.83E+06 - - - 4.9608 0.9674 221125_WJC_METTL3_EV_vs_WT_F08.23976.23976.4 9.91E-07 11/204 K.QSKPVTTPEEIAQVATISANGDKEIGNIISDAMKK.V "sp|P10809|CH60_HUMAN,tr|A0A7I2V599|A0A7I2V599_HUMAN,tr|E7EXB4|E7EXB4_HUMAN,tr|A0A7I2YQ71|A0A7I2YQ71_HUMAN,tr|E7ESH4|E7ESH4_HUMAN,tr|A0A7I2V5M1|A0A7I2V5M1_HUMAN,tr|A0A7I2V5K3|A0A7I2V5K3_HUMAN,tr|A0A7I2V369|A0A7I2V369_HUMAN" 8 3682.9088 2.77 123788 23976 4 3683.900686 921.7345 "60 kDa heat shock protein, mitochondrial OS=Homo sapiens OX=9606 GN=HSPD1 PE=1 SV=2" 4.94 3841.6 - 140306 - - - 269.3333 - 2.54 0.471 - 35.8 1 2 1 0.9919 35 0 0 0 1.13E+06 4.09E+05 - - - 3.3272 1 221125_WJC_METTL3_EV_vs_WT_F08.23980.23980.4 8.84E-10 16/168 R.K[136.11]DGNASGTTLLEALDC[160.03]ILPPTR[166.11]PTDK[136.11]PLR[166.11].L "sp|P68104|EF1A1_HUMAN,sp|Q5VTE0|EF1A3_HUMAN,tr|A0A7I2V659|A0A7I2V659_HUMAN,tr|A0A7I2V3H3|A0A7I2V3H3_HUMAN,tr|A0A7I2V5N4|A0A7I2V5N4_HUMAN,tr|A0A087WVQ9|A0A087WVQ9_HUMAN,tr|A0A087WV01|A0A087WV01_HUMAN" 7 3184.7 0.27 123790 23980 4 3184.702151 797.1823 Elongation factor 1-alpha 1 OS=Homo sapiens OX=9606 GN=EEF1A1 PE=1 SV=1 6.16 3842.2 - 582835 - - - 0.6792 - 3.056 0.656 - 126.2 1 2 0 0.0022 29 0 0 0 7.03E+06 2.59E+07 - - - 5.2795 1 221125_WJC_METTL3_EV_vs_WT_F08.23981.23981.3 5.26E-17 26/112 K.DIENQYETQITQIEHEVSSSGQEVQSSAK.E "sp|P35527|K1C9_HUMAN,tr|K7EQQ3|K7EQQ3_HUMAN" 2 3263.5066 212.46 123791 23981 3 3263.508132 1088.8428 "Keratin, type I cytoskeletal 9 OS=Homo sapiens OX=9606 GN=KRT9 PE=1 SV=3" 4.14 3842.3 - 695723 - - - 0.4728 - 5.322 0.733 - 892.7 1 2 0 0.0015 29 0 0 0 4.21E+09 1.98E+07 - - - 10.5581 1 221125_WJC_METTL3_EV_vs_WT_F08.23982.23982.3 3.16E-09 19/80 R.K[136.11]HAASDVDLEIESLLNQQSTK[136.11].E "sp|Q86U44|MTA70_HUMAN,tr|F5H6D8|F5H6D8_HUMAN,tr|H0YFV6|H0YFV6_HUMAN,tr|B4DTN4|B4DTN4_HUMAN" 4 2341.2096 0.01 123792 23982 3 2341.208182 781.4105 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 4.75 3842.4 - 335330 - - - -0.6138 - 3.603 0.574 - 528 1 2 0 -0.0014 21 0 0 0 1.52E+05 1.52E+07 - - - 8.0121 1 221125_WJC_METTL3_EV_vs_WT_F08.23983.23983.4 1.84E-16 26/198 K.TQEDEEEISTSPGVSEFVSDAFDAC[160.03]NLNQEDLRK.E sp|Q96A49|SYAP1_HUMAN 1 3858.7014 1.93 123793 23983 4 3858.698196 965.6826 Synapse-associated protein 1 OS=Homo sapiens OX=9606 GN=SYAP1 PE=1 SV=1 3.76 3842.6 - 279083 - - - -0.8308 - 5.054 0.788 - 327 1 2 0 -0.0032 34 0 0 0 8.16E+06 4.23E+06 - - - 6.567 1 221125_WJC_METTL3_EV_vs_WT_F08.23984.23984.4 4.07E-10 10/168 K.DIENQYETQITQIEHEVSSSGQEVQSSAK.E "sp|P35527|K1C9_HUMAN,tr|K7EQQ3|K7EQQ3_HUMAN" 2 3263.5066 276.16 123794 23984 4 3263.508028 816.8839 "Keratin, type I cytoskeletal 9 OS=Homo sapiens OX=9606 GN=KRT9 PE=1 SV=3" 4.14 3842.7 - 235635 - - - 0.4409 - 3.023 0.594 - 42.3 1 2 0 0.0014 29 0 0 0 1.64E+09 5.93E+06 - - - 4.7367 1 221125_WJC_METTL3_EV_vs_WT_F08.23988.23988.3 2.27E-11 24/132 K.TQEDEEEISTSPGVSEFVSDAFDAC[160.03]NLNQEDLRK.E sp|Q96A49|SYAP1_HUMAN 1 3858.7014 1.52 123796 23988 3 3858.705114 1287.2411 Synapse-associated protein 1 OS=Homo sapiens OX=9606 GN=SYAP1 PE=1 SV=1 3.76 3843.3 - 305088 - - - 0.962 - 4.943 0.767 - 387.9 1 2 0 0.0037 34 0 0 0 5.43E+06 3.57E+06 - - - 10.7666 0.9922 221125_WJC_METTL3_EV_vs_WT_F08.23995.23995.4 0.0595 10/234 K.QK[136.11]GDTPASATAPTEAAQIISAAGDTLSVPAPAVQPEESLK[136.11].T sp|Q16891|MIC60_HUMAN 1 3933.019 1.45 123801 23995 4 3933.013147 984.262 MICOS complex subunit MIC60 OS=Homo sapiens OX=9606 GN=IMMT PE=1 SV=1 4.18 3844.2 - 412126 - - - -1.4811 - 2.377 0.266 - 25.7 1 2 1 -0.0058 40 0 0 0 5.93E+07 4.08E+07 - - - 1.7896 1 221125_WJC_METTL3_EV_vs_WT_F08.23996.23996.3 4.56E-05 14/120 K.ELEQVC[160.03]NPIISGLYQGAGGPGPGGFGAQGPK[136.11].G "sp|P0DMV8|HS71A_HUMAN,sp|P0DMV9|HS71B_HUMAN,tr|V9GZ37|V9GZ37_HUMAN,tr|A0A0G2JIW1|A0A0G2JIW1_HUMAN" 4 3062.5011 0.02 123802 23996 3 3062.498756 1021.841 Heat shock 70 kDa protein 1A OS=Homo sapiens OX=9606 GN=HSPA1A PE=1 SV=1 4.53 3844.3 - 145191 - - - -0.7719 - 3.07 0.604 - 122.8 1 2 0 -0.0024 31 0 0 0 1.45E+05 7.09E+06 - - - 7.8539 1 221125_WJC_METTL3_EV_vs_WT_F08.24002.24002.4 0.00613 17/168 R.KDGNASGTTLLEALDC[160.03]ILPPTRPTDKPLR.L "sp|P68104|EF1A1_HUMAN,sp|Q5VTE0|EF1A3_HUMAN,tr|A0A7I2V659|A0A7I2V659_HUMAN,tr|A0A7I2V3H3|A0A7I2V3H3_HUMAN,tr|A0A7I2V5N4|A0A7I2V5N4_HUMAN,tr|A0A087WVQ9|A0A087WVQ9_HUMAN,tr|A0A087WV01|A0A087WV01_HUMAN" 7 3148.655 0.27 123806 24002 4 3148.656151 788.171 Elongation factor 1-alpha 1 OS=Homo sapiens OX=9606 GN=EEF1A1 PE=1 SV=1 6.16 3845.1 - 1.19E+06 - - - 0.3503 - 2.965 0.485 - 101.1 1 2 0 0.0011 29 0 0 0 7.00E+06 2.59E+07 - - - 3.7821 1 221125_WJC_METTL3_EV_vs_WT_F08.24012.24012.2 1.30E-11 Jul-56 K.DIENQYETQITQIEHEVSSSGQEVQSSAK.E "sp|P35527|K1C9_HUMAN,tr|K7EQQ3|K7EQQ3_HUMAN" 2 3263.5066 999 123812 24012 2 3263.502097 1632.7606 "Keratin, type I cytoskeletal 9 OS=Homo sapiens OX=9606 GN=KRT9 PE=1 SV=3" 4.14 3846.4 - 522522 - - - -1.3764 - 2.341 0.701 - 32.6 1 2 0 -0.0045 29 0 0 0 1.33E+07 0.00E+00 - - - 6.3084 0.9996 221125_WJC_METTL3_EV_vs_WT_F08.24014.24014.2 9.55E-05 26-Jul K.AFYPEEISSMVLTK[136.11].M "sp|P0DMV8|HS71A_HUMAN,sp|P34931|HS71L_HUMAN,sp|P0DMV9|HS71B_HUMAN,tr|Q53FA3|Q53FA3_HUMAN,tr|A0A0G2JIW1|A0A0G2JIW1_HUMAN" 5 1621.8153 0.2 123814 24014 2 1621.813603 811.9149 Heat shock 70 kDa protein 1A OS=Homo sapiens OX=9606 GN=HSPA1A PE=1 SV=1 4.53 3846.7 - 135834 - - - -1.0439 - 1.551 0.463 - 91.4 1 2 0 -0.0017 14 0 0 0 8.41E+05 4.23E+06 - - - 3.5616 0.9995 221125_WJC_METTL3_EV_vs_WT_F08.24056.24056.3 0.00606 Jun-56 R.STSHK[136.11]PDEIYGMIER[166.11].L sp|Q86U44|MTA70_HUMAN 1 1779.8581 0.03 123822 24056 3 1779.855325 594.2933 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 5.42 3853 - 149247 - - - -1.5333 - 1.551 0.394 - 44.5 1 2 0 -0.0027 15 0 0 0 3.10E+05 9.72E+06 - - - 4.0772 0.9973 221125_WJC_METTL3_EV_vs_WT_F08.24085.24085.2 0.00981 18-Jun K.LLEPVLLLGK.E "sp|P62249|RS16_HUMAN,tr|M0R210|M0R210_HUMAN,tr|M0R3H0|M0R3H0_HUMAN,tr|M0QX76|M0QX76_HUMAN,tr|M0R1M5|M0R1M5_HUMAN,tr|Q6IPX4|Q6IPX4_HUMAN" 6 1093.7111 0.83 123831 24085 2 1093.708156 547.8628 40S ribosomal protein S16 OS=Homo sapiens OX=9606 GN=RPS16 PE=1 SV=2 6 3857.2 - 60320.5 - - - -2.6762 - 1.324 0.375 - 90.6 1 2 0 -0.0029 10 0 0 0 3.64E+06 4.39E+06 - - - 2.5932 0.9959 221125_WJC_METTL3_EV_vs_WT_F08.24091.24091.3 0.0263 May-52 K.K[136.11]GPGEVAGTVTGQK[136.11].R "sp|Q86U44|MTA70_HUMAN,tr|F5H6D8|F5H6D8_HUMAN,tr|H0YFV6|H0YFV6_HUMAN,tr|B4DTN4|B4DTN4_HUMAN" 4 1343.738 0.001 123835 24091 3 1343.734608 448.9199 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 8.59 3858 - 99692.5 - - - -2.5087 - 1.054 0.387 - 26.1 1 2 0 -0.0034 14 0 0 0 0.00E+00 4.74E+06 - - - 2.9935 0.9966 221125_WJC_METTL3_EV_vs_WT_F08.24105.24105.2 0.0125 24-Jun K.TLNDELEIIEGMK.F "sp|P10809|CH60_HUMAN,tr|A0A7I2V2X6|A0A7I2V2X6_HUMAN,tr|A0A7I2V599|A0A7I2V599_HUMAN,tr|E7EXB4|E7EXB4_HUMAN,tr|A0A7I2YQ71|A0A7I2YQ71_HUMAN,tr|E7ESH4|E7ESH4_HUMAN,tr|A0A7I2V5M1|A0A7I2V5M1_HUMAN,tr|A0A7I2V5K3|A0A7I2V5K3_HUMAN,tr|A0A7I2V369|A0A7I2V369_HUMAN" 9 1503.7491 1.53 123840 24105 2 1503.753167 752.8818 "60 kDa heat shock protein, mitochondrial OS=Homo sapiens OX=9606 GN=HSPD1 PE=1 SV=2" 4 3860.2 - 55134.6 - - - 2.7305 - 1.043 0.448 - 71.1 1 2 0 0.0041 13 0 0 0 2.60E+06 1.70E+06 - - - 2.4567 0.8444 221125_WJC_METTL3_EV_vs_WT_F08.24109.24109.3 0.0515 3/124 R.AEQDSTTVAAFASSLVSGLNSSASEPAK[136.11]EPAK[136.11].K "sp|Q86U44|MTA70_HUMAN,tr|F5H6D8|F5H6D8_HUMAN,tr|H0YFV6|H0YFV6_HUMAN,tr|B4DTN4|B4DTN4_HUMAN" 4 3165.5648 0.001 123843 24109 3 3165.570675 1056.1956 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 4.41 3860.7 - 66892.1 - - - 1.8458 - 0.862 0.281 - 6.8 1 2 1 0.0058 32 0 0 0 0.00E+00 1.48E+06 - - - 1.3296 0.9972 221125_WJC_METTL3_EV_vs_WT_F08.24115.24115.2 0.0543 18-Jun K.LLEPVLLLGK[136.11].E "sp|P62249|RS16_HUMAN,tr|M0R210|M0R210_HUMAN,tr|M0R3H0|M0R3H0_HUMAN,tr|M0QX76|M0QX76_HUMAN,tr|M0R1M5|M0R1M5_HUMAN,tr|Q6IPX4|Q6IPX4_HUMAN" 6 1101.7253 0.83 123847 24115 2 1101.72679 551.8699 40S ribosomal protein S16 OS=Homo sapiens OX=9606 GN=RPS16 PE=1 SV=2 6 3861.4 - 127276 - - - 1.3679 - 1.128 0.34 - 100 1 2 0 0.0015 10 0 0 0 3.64E+06 4.39E+06 - - - 1.888 0.9986 221125_WJC_METTL3_EV_vs_WT_F08.24117.24117.2 9.60E-05 24-Aug K.TLNDELEIIEGMK[136.11].F "sp|P10809|CH60_HUMAN,tr|A0A7I2V2X6|A0A7I2V2X6_HUMAN,tr|A0A7I2V599|A0A7I2V599_HUMAN,tr|E7EXB4|E7EXB4_HUMAN,tr|A0A7I2YQ71|A0A7I2YQ71_HUMAN,tr|E7ESH4|E7ESH4_HUMAN,tr|A0A7I2V5M1|A0A7I2V5M1_HUMAN,tr|A0A7I2V5K3|A0A7I2V5K3_HUMAN,tr|A0A7I2V369|A0A7I2V369_HUMAN" 9 1511.7633 1.53 123849 24117 2 1511.768315 756.8889 "60 kDa heat shock protein, mitochondrial OS=Homo sapiens OX=9606 GN=HSPD1 PE=1 SV=2" 4 3861.7 - 70876.1 - - - 3.3431 - 1.848 0.435 - 120.5 1 2 0 0.0051 13 0 0 0 2.60E+06 1.70E+06 - - - 3.8284 0.9447 221125_WJC_METTL3_EV_vs_WT_F08.24128.24128.4 0.568 4/102 K.STSESFIQHIVSLVHHVK.E "sp|Q9NYF8|BCLF1_HUMAN,tr|E9PKI6|E9PKI6_HUMAN,tr|A0A1W2PQ43|A0A1W2PQ43_HUMAN,tr|E9PK91|E9PK91_HUMAN,tr|E9PJA7|E9PJA7_HUMAN,tr|E9PK09|E9PK09_HUMAN,tr|E9PQN2|E9PQN2_HUMAN" 7 2047.0851 2.09 123853 24128 4 2047.08853 512.7785 Bcl-2-associated transcription factor 1 OS=Homo sapiens OX=9606 GN=BCLAF1 PE=1 SV=2 6.78 3863.2 - 234768 - - - 1.6883 - 0.958 0.194 - 10.5 2 2 0 0.0035 18 0 0 0 4.37E+08 2.09E+08 - - - 0.6695 0.9727 221125_WJC_METTL3_EV_vs_WT_F08.24129.24129.3 0.000479 7/128 R.SDSPVPTAPTSGGPK[136.11]PSTASAVPELATDPELEK[136.11].K "sp|Q86U44|MTA70_HUMAN,tr|B4E349|B4E349_HUMAN,tr|F5H6D8|F5H6D8_HUMAN,tr|B4DTN4|B4DTN4_HUMAN" 4 3248.6271 0.001 123854 24129 3 3249.634682 1083.883 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 4.18 3863.3 - 83421.2 - - - 310.1569 - 1.628 0.371 - 22.8 1 2 0 1.0076 33 0 0 0 0.00E+00 7.65E+06 - - - 3.5184 1 221125_WJC_METTL3_EV_vs_WT_F08.24134.24134.4 0.000185 7/102 K.STSESFIQHIVSLVHHVK[136.11].E "sp|Q9NYF8|BCLF1_HUMAN,tr|E9PKI6|E9PKI6_HUMAN,tr|A0A1W2PQ43|A0A1W2PQ43_HUMAN,tr|E9PK91|E9PK91_HUMAN,tr|E9PJA7|E9PJA7_HUMAN,tr|E9PK09|E9PK09_HUMAN,tr|E9PQN2|E9PQN2_HUMAN" 7 2055.0993 2.09 123857 24134 4 2055.103157 514.7821 Bcl-2-associated transcription factor 1 OS=Homo sapiens OX=9606 GN=BCLAF1 PE=1 SV=2 6.78 3864 - 193001 - - - 1.8894 - 1.625 0.526 - 30.3 1 2 0 0.0039 18 0 0 0 4.37E+08 2.09E+08 - - - 3.9695 0.9999 221125_WJC_METTL3_EV_vs_WT_F08.24139.24139.3 5.86E-08 Sep-68 K.STSESFIQHIVSLVHHVK.E "sp|Q9NYF8|BCLF1_HUMAN,tr|E9PKI6|E9PKI6_HUMAN,tr|A0A1W2PQ43|A0A1W2PQ43_HUMAN,tr|E9PK91|E9PK91_HUMAN,tr|E9PJA7|E9PJA7_HUMAN,tr|E9PK09|E9PK09_HUMAN,tr|E9PQN2|E9PQN2_HUMAN" 7 2047.0851 2.05 123860 24139 3 2047.090901 683.369 Bcl-2-associated transcription factor 1 OS=Homo sapiens OX=9606 GN=BCLAF1 PE=1 SV=2 6.78 3864.7 - 250999 - - - 2.8465 - 2.286 0.614 - 87 1 2 0 0.0058 18 0 0 0 1.49E+08 7.29E+07 - - - 7.4427 1 221125_WJC_METTL3_EV_vs_WT_F08.24152.24152.3 2.70E-09 13/68 K.STSESFIQHIVSLVHHVK[136.11].E "sp|Q9NYF8|BCLF1_HUMAN,tr|E9PKI6|E9PKI6_HUMAN,tr|A0A1W2PQ43|A0A1W2PQ43_HUMAN,tr|E9PK91|E9PK91_HUMAN,tr|E9PJA7|E9PJA7_HUMAN,tr|E9PK09|E9PK09_HUMAN,tr|E9PQN2|E9PQN2_HUMAN" 7 2055.0993 2.05 123867 24152 3 2055.102166 686.0404 Bcl-2-associated transcription factor 1 OS=Homo sapiens OX=9606 GN=BCLAF1 PE=1 SV=2 6.78 3866.6 - 99896.5 - - - 1.4072 - 2.748 0.603 - 199.3 1 2 0 0.0029 18 0 0 0 1.49E+08 7.29E+07 - - - 7.7792 0.9899 221125_WJC_METTL3_EV_vs_WT_F08.24161.24161.3 6.62E-05 Aug-44 F.IQHIVSLVHHVK.E "sp|Q9NYF8|BCLF1_HUMAN,tr|E9PKI6|E9PKI6_HUMAN,tr|A0A1W2PQ43|A0A1W2PQ43_HUMAN,tr|E9PK91|E9PK91_HUMAN,tr|E9PJA7|E9PJA7_HUMAN,tr|E9PK09|E9PK09_HUMAN,tr|E9PQN2|E9PQN2_HUMAN" 7 1408.8303 2.03 123874 24161 3 1408.828047 470.6174 Bcl-2-associated transcription factor 1 OS=Homo sapiens OX=9606 GN=BCLAF1 PE=1 SV=2 8.77 3867.8 - 195692 - - - -1.6013 - 1.683 0.499 - 69.8 1 1 0 -0.0023 12 0 0 0 1.12E+07 5.50E+06 - - - 5.5457 0.9363 221125_WJC_METTL3_EV_vs_WT_F08.24166.24166.3 0.0196 Jun-60 T.SESFIQHIVSLVHHVK[136.11].E "sp|Q9NYF8|BCLF1_HUMAN,tr|E9PKI6|E9PKI6_HUMAN,tr|A0A1W2PQ43|A0A1W2PQ43_HUMAN,tr|E9PK91|E9PK91_HUMAN,tr|E9PJA7|E9PJA7_HUMAN,tr|E9PK09|E9PK09_HUMAN,tr|E9PQN2|E9PQN2_HUMAN" 7 1867.0196 2.14 123877 24166 3 1867.020549 623.3471 Bcl-2-associated transcription factor 1 OS=Homo sapiens OX=9606 GN=BCLAF1 PE=1 SV=2 6.78 3868.5 - 77781.3 - - - 0.526 - 1.443 0.372 - 35.5 1 1 0 0.001 16 0 0 0 9.36E+06 4.38E+06 - - - 3.6281 0.9915 221125_WJC_METTL3_EV_vs_WT_F08.24167.24167.3 6.57E-06 Sep-60 T.SESFIQHIVSLVHHVK.E "sp|Q9NYF8|BCLF1_HUMAN,tr|E9PKI6|E9PKI6_HUMAN,tr|A0A1W2PQ43|A0A1W2PQ43_HUMAN,tr|E9PK91|E9PK91_HUMAN,tr|E9PJA7|E9PJA7_HUMAN,tr|E9PK09|E9PK09_HUMAN,tr|E9PQN2|E9PQN2_HUMAN" 7 1859.0054 2.13 123878 24167 3 1859.011004 620.6757 Bcl-2-associated transcription factor 1 OS=Homo sapiens OX=9606 GN=BCLAF1 PE=1 SV=2 6.78 3868.7 - 104597 - - - 3.0323 - 2.343 0.563 - 70.3 1 1 0 0.0056 16 0 0 0 9.35E+06 4.38E+06 - - - 7 1 221125_WJC_METTL3_EV_vs_WT_F08.24178.24178.2 1.67E-09 Nov-34 K.STSESFIQHIVSLVHHVK.E "sp|Q9NYF8|BCLF1_HUMAN,tr|E9PKI6|E9PKI6_HUMAN,tr|A0A1W2PQ43|A0A1W2PQ43_HUMAN,tr|E9PK91|E9PK91_HUMAN,tr|E9PJA7|E9PJA7_HUMAN,tr|E9PK09|E9PK09_HUMAN,tr|E9PQN2|E9PQN2_HUMAN" 7 2047.0851 2.07 123885 24178 2 2047.087559 1024.5498 Bcl-2-associated transcription factor 1 OS=Homo sapiens OX=9606 GN=BCLAF1 PE=1 SV=2 6.78 3870.2 - 68720.5 - - - 1.2139 - 2.433 0.7 - 298.9 1 2 0 0.0025 18 0 0 0 5.67E+06 2.74E+06 - - - 6.3964 0.9999 221125_WJC_METTL3_EV_vs_WT_F08.24190.24190.4 2.68E-06 20/120 R.K[136.11]HAASDVDLEIESLLNQQSTK[136.11].E "sp|Q86U44|MTA70_HUMAN,tr|F5H6D8|F5H6D8_HUMAN,tr|H0YFV6|H0YFV6_HUMAN,tr|B4DTN4|B4DTN4_HUMAN" 4 2341.2096 0.01 123890 24190 4 2341.201655 586.3097 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 4.75 3872 - 340470 - - - -3.4017 - 3.757 0.531 - 320.8 1 2 0 -0.008 21 0 0 0 2.88E+05 2.58E+07 - - - 4.2833 0.9971 221125_WJC_METTL3_EV_vs_WT_F08.24194.24194.3 0.000241 13/44 F.IQHIVSLVHHVK[136.11].E "sp|Q9NYF8|BCLF1_HUMAN,tr|E9PKI6|E9PKI6_HUMAN,tr|A0A1W2PQ43|A0A1W2PQ43_HUMAN,tr|E9PK91|E9PK91_HUMAN,tr|E9PJA7|E9PJA7_HUMAN,tr|E9PK09|E9PK09_HUMAN,tr|E9PQN2|E9PQN2_HUMAN" 7 1416.8445 2.05 123891 24194 3 1416.844627 473.2888 Bcl-2-associated transcription factor 1 OS=Homo sapiens OX=9606 GN=BCLAF1 PE=1 SV=2 8.77 3872.6 - 227862 - - - 0.0875 - 2.525 0.495 - 189.1 1 1 0 0.0001 12 0 0 0 1.12E+07 5.46E+06 - - - 6.6261 1 221125_WJC_METTL3_EV_vs_WT_F08.24203.24203.3 3.33E-07 16/80 R.K[136.11]HAASDVDLEIESLLNQQSTK[136.11].E "sp|Q86U44|MTA70_HUMAN,tr|F5H6D8|F5H6D8_HUMAN,tr|H0YFV6|H0YFV6_HUMAN,tr|B4DTN4|B4DTN4_HUMAN" 4 2341.2096 0.01 123894 24203 3 2341.212662 781.4105 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 4.75 3873.7 - 229603 - - - 1.2998 - 3.662 0.543 - 356.6 1 2 0 0.003 21 0 0 0 1.44E+05 1.62E+07 - - - 7.705 0.9998 221125_WJC_METTL3_EV_vs_WT_F08.24204.24204.3 1.71E-09 9/112 K.DIENQYETQITQIEHEVSSSGQEVQSSAK.E "sp|P35527|K1C9_HUMAN,tr|K7EQQ3|K7EQQ3_HUMAN" 2 3263.5066 999 123895 24204 3 3263.493494 1088.8428 "Keratin, type I cytoskeletal 9 OS=Homo sapiens OX=9606 GN=KRT9 PE=1 SV=3" 4.14 3873.9 - 88725.9 - - - -4.0126 - 2.555 0.563 - 61.7 1 2 0 -0.0131 29 0 0 0 5.94E+06 0.00E+00 - - - 6.9714 0.9985 221125_WJC_METTL3_EV_vs_WT_F08.24205.24205.4 4.60E-11 19/198 K.DHTPSQELALTQSVGGDSSADR[166.11]LFPPQWIC[160.03]C[160.03]DIR[166.11].Y sp|Q86U44|MTA70_HUMAN 1 3875.811 0.001 123896 24205 4 3876.810985 969.96 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 4.35 3874 - 197630 - - - 258.0035 - 3.278 0.628 - 133 1 2 1 1 34 0 0 0 0.00E+00 1.13E+07 - - - 4.7692 0.9999 221125_WJC_METTL3_EV_vs_WT_F08.24221.24221.4 0.000266 6/174 K.KSEAAVPPWVDTNDEETIQQQILALSADKR.N sp|Q96A49|SYAP1_HUMAN 1 3351.6947 1.22 123901 24221 4 3351.703401 838.9309 Synapse-associated protein 1 OS=Homo sapiens OX=9606 GN=SYAP1 PE=1 SV=1 4.3 3876.3 - 37702.8 - - - 2.6067 - 1.453 0.518 - 14.8 1 2 0 0.0087 30 0 0 0 3.11E+06 2.55E+06 - - - 3.8466 0.9309 221125_WJC_METTL3_EV_vs_WT_F08.24248.24248.4 3.1 4/108 R.GLLQDDAHPTLVTYADHSK[136.11].L "sp|Q86U44|MTA70_HUMAN,tr|F5H6D8|F5H6D8_HUMAN,tr|H0YFV6|H0YFV6_HUMAN,tr|B4DTN4|B4DTN4_HUMAN" 4 2088.0367 0.001 123913 24248 4 2088.03698 523.0165 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 5.13 3880.4 - 71299 - - - 0.1183 - 0.807 0.156 - 6.6 1 2 0 0.0002 19 0 0 0 0.00E+00 3.00E+06 - - - 0.5112 0.9991 221125_WJC_METTL3_EV_vs_WT_F08.24265.24265.4 1.87E-05 14/168 R.R[166.11]AEQDSTTVAAFASSLVSGLNSSASEPAK[136.11].E "sp|Q86U44|MTA70_HUMAN,tr|F5H6D8|F5H6D8_HUMAN,tr|H0YFV6|H0YFV6_HUMAN,tr|B4DTN4|B4DTN4_HUMAN" 4 2898.4326 0 123922 24265 4 2898.452776 725.6154 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 4.68 3883 - 197083 - - - 6.9679 - 3.272 0.567 - 78.5 1 2 0 0.0202 29 0 0 0 1.30E+04 3.38E+06 - - - 4.5209 0.9998 221125_WJC_METTL3_EV_vs_WT_F08.24280.24280.3 0.000246 Jun-88 R.IITITGTQDQIQNAQYLLQNSVK.Q sp|P61978|HNRPK_HUMAN 1 2588.381 3.2 123931 24280 3 2588.3821 863.8009 Heterogeneous nuclear ribonucleoprotein K OS=Homo sapiens OX=9606 GN=HNRNPK PE=1 SV=1 5.83 3885 - 39422.1 - - - 0.4319 - 1.724 0.415 - 36.8 1 2 0 0.0011 23 0 0 0 7.32E+05 2.29E+05 - - - 4.4442 0.9962 221125_WJC_METTL3_EV_vs_WT_F08.24289.24289.3 0.0496 May-56 R.STSHK[136.11]PDEIYGMIER[166.11].L sp|Q86U44|MTA70_HUMAN 1 1779.8581 0.02 123936 24289 3 1779.859822 594.2933 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 5.42 3886.3 - 95234.9 - - - 0.9933 - 1.2 0.31 - 25.5 1 2 0 0.0018 15 0 0 0 1.51E+05 8.14E+06 - - - 2.4714 0.9997 221125_WJC_METTL3_EV_vs_WT_F08.24303.24303.3 0.00549 Jun-52 K.K[136.11]GPGEVAGTVTGQK[136.11].R "sp|Q86U44|MTA70_HUMAN,tr|F5H6D8|F5H6D8_HUMAN,tr|H0YFV6|H0YFV6_HUMAN,tr|B4DTN4|B4DTN4_HUMAN" 4 1343.738 0.001 123943 24303 3 1343.739029 448.9199 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 8.59 3888.5 - 64079.1 - - - 0.7814 - 1.453 0.42 - 31 1 2 0 0.001 14 0 0 0 0.00E+00 3.48E+06 - - - 4.2152 0.9995 221125_WJC_METTL3_EV_vs_WT_F08.24317.24317.3 3.53E-10 16/112 R.R[166.11]AEQDSTTVAAFASSLVSGLNSSASEPAK[136.11].E "sp|Q86U44|MTA70_HUMAN,tr|F5H6D8|F5H6D8_HUMAN,tr|H0YFV6|H0YFV6_HUMAN,tr|B4DTN4|B4DTN4_HUMAN" 4 2898.4326 0.06 123951 24317 3 2898.451978 967.1515 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 4.68 3890.5 - 311610 - - - 6.6926 - 3.401 0.632 - 199.8 1 2 0 0.0194 29 0 0 0 5.18E+05 8.22E+06 - - - 8.3969 0.9997 221125_WJC_METTL3_EV_vs_WT_F08.24339.24339.4 0.00594 5/102 K.STSESFIQHIVSLVHHVK.E "sp|Q9NYF8|BCLF1_HUMAN,tr|E9PKI6|E9PKI6_HUMAN,tr|A0A1W2PQ43|A0A1W2PQ43_HUMAN,tr|E9PK91|E9PK91_HUMAN,tr|E9PJA7|E9PJA7_HUMAN,tr|E9PK09|E9PK09_HUMAN,tr|E9PQN2|E9PQN2_HUMAN" 7 2047.0851 2.09 123960 24339 4 2047.086372 512.7785 Bcl-2-associated transcription factor 1 OS=Homo sapiens OX=9606 GN=BCLAF1 PE=1 SV=2 6.78 3893.6 - 71496.5 - - - 0.6341 - 1.396 0.383 - 17 1 2 0 0.0013 18 0 0 0 4.37E+08 2.09E+08 - - - 2.6736 0.9998 221125_WJC_METTL3_EV_vs_WT_F08.24360.24360.3 8.31E-06 Aug-84 K.EKPYFPIPEEYTFIQNVPLEDR.V "sp|Q00839|HNRPU_HUMAN,tr|A0A1W2PQL0|A0A1W2PQL0_HUMAN,tr|A0A1W2PPL4|A0A1W2PPL4_HUMAN,tr|A0A1W2PQ74|A0A1W2PQ74_HUMAN,tr|Q5RI18|Q5RI18_HUMAN,tr|A0A1W2PP35|A0A1W2PP35_HUMAN,tr|A0A1W2PPS1|A0A1W2PPS1_HUMAN,tr|A0A1W2PRZ7|A0A1W2PRZ7_HUMAN,tr|A0A1W2PPH7|A0A1W2PPH7_HUMAN,tr|A0A1W2PP34|A0A1W2PP34_HUMAN,tr|A0A1X7SBS1|A0A1X7SBS1_HUMAN" 11 2723.3483 1.22 123970 24360 3 2723.356849 908.79 Heterogeneous nuclear ribonucleoprotein U OS=Homo sapiens OX=9606 GN=HNRNPU PE=1 SV=6 4.25 3896.4 - 68959.7 - - - 3.145 - 1.76 0.545 - 51.2 1 2 0 0.0086 22 0 0 0 8.85E+06 7.27E+06 - - - 5.9541 0.9997 221125_WJC_METTL3_EV_vs_WT_F08.24363.24363.3 0.00012 Jun-84 K.EK[136.11]PYFPIPEEYTFIQNVPLEDR[166.11].V "sp|Q00839|HNRPU_HUMAN,tr|A0A1W2PQL0|A0A1W2PQL0_HUMAN,tr|A0A1W2PPL4|A0A1W2PPL4_HUMAN,tr|A0A1W2PQ74|A0A1W2PQ74_HUMAN,tr|Q5RI18|Q5RI18_HUMAN,tr|A0A1W2PP35|A0A1W2PP35_HUMAN,tr|A0A1W2PPS1|A0A1W2PPS1_HUMAN,tr|A0A1W2PRZ7|A0A1W2PRZ7_HUMAN,tr|A0A1W2PPH7|A0A1W2PPH7_HUMAN,tr|A0A1W2PP34|A0A1W2PP34_HUMAN,tr|A0A1X7SBS1|A0A1X7SBS1_HUMAN" 11 2741.3708 1.23 123973 24363 3 2741.365939 914.7975 Heterogeneous nuclear ribonucleoprotein U OS=Homo sapiens OX=9606 GN=HNRNPU PE=1 SV=6 4.25 3896.7 - 62939 - - - -1.7564 - 1.658 0.432 - 30.1 1 2 0 -0.0048 22 0 0 0 8.85E+06 7.22E+06 - - - 4.5538 0.8292 221125_WJC_METTL3_EV_vs_WT_F08.24392.24392.4 0.21 5/192 R.SDSPVPTAPTSGGPK[136.11]PSTASAVPELATDPELEK[136.11].K "sp|Q86U44|MTA70_HUMAN,tr|B4E349|B4E349_HUMAN,tr|F5H6D8|F5H6D8_HUMAN,tr|B4DTN4|B4DTN4_HUMAN" 4 3248.6271 0.05 123988 24392 4 3249.633655 813.1641 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 4.18 3900.7 - 35760.1 - - - 309.8407 - 1.122 0.265 - 9.7 1 2 0 1.0066 33 0 0 0 2.72E+04 5.61E+05 - - - 1.2883 0.8334 221125_WJC_METTL3_EV_vs_WT_F08.24401.24401.2 0.0249 26-Apr K.K[136.11]VSQEILELLNTTT.A "sp|Q86U44|MTA70_HUMAN,tr|H0YFV6|H0YFV6_HUMAN" 2 1595.8862 0.001 123993 24401 2 1595.884114 798.9504 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 4.53 3902 - 23902.6 - - - -1.2777 - 1.033 0.341 - 47.5 1 1 0 -0.002 14 0 0 0 0.00E+00 1.55E+05 - - - 1.6405 0.9942 221125_WJC_METTL3_EV_vs_WT_F08.24409.24409.3 6.56E-07 Oct-64 A.SDVDLEIESLLNQQSTK[136.11].E "sp|Q86U44|MTA70_HUMAN,tr|F5H6D8|F5H6D8_HUMAN,tr|H0YFV6|H0YFV6_HUMAN,tr|B4DTN4|B4DTN4_HUMAN" 4 1925.9673 0.01 123998 24409 3 1925.970305 642.9964 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 3.92 3903.2 - 139314 - - - 1.5514 - 2.202 0.511 - 125.1 1 1 0 0.003 17 0 0 0 1.82E+05 1.97E+07 - - - 6.2305 0.9999 221125_WJC_METTL3_EV_vs_WT_F08.24429.24429.4 1.05E-07 19/120 R.K[136.11]HAASDVDLEIESLLNQQSTK[136.11].E "sp|Q86U44|MTA70_HUMAN,tr|F5H6D8|F5H6D8_HUMAN,tr|H0YFV6|H0YFV6_HUMAN,tr|B4DTN4|B4DTN4_HUMAN" 4 2341.2096 0.01 124007 24429 4 2341.200619 586.3097 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 4.75 3906.1 - 511831 - - - -3.8442 - 3.491 0.544 - 293.7 1 2 0 -0.009 21 0 0 0 2.26E+05 2.84E+07 - - - 4.3718 0.9899 221125_WJC_METTL3_EV_vs_WT_F08.24430.24430.3 5.86E-08 15/80 R.K[136.11]HAASDVDLEIESLLNQQSTK[136.11].E "sp|Q86U44|MTA70_HUMAN,tr|F5H6D8|F5H6D8_HUMAN,tr|H0YFV6|H0YFV6_HUMAN,tr|B4DTN4|B4DTN4_HUMAN" 4 2341.2096 0.001 124008 24430 3 2342.200962 781.4105 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 4.75 3906.2 - 286587 - - - 423.432 - 3.157 0.542 - 305.6 1 2 0 0.9913 21 0 0 0 0.00E+00 9.53E+06 - - - 7.0643 1 221125_WJC_METTL3_EV_vs_WT_F08.24462.24462.3 3.44E-11 18/68 A.ASDVDLEIESLLNQQSTK[136.11].E "sp|Q86U44|MTA70_HUMAN,tr|F5H6D8|F5H6D8_HUMAN,tr|H0YFV6|H0YFV6_HUMAN,tr|B4DTN4|B4DTN4_HUMAN" 4 1997.0044 0.001 124016 24462 3 1997.999847 666.6754 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 3.92 3911 - 585732 - - - 498.4551 - 3.718 0.626 - 480.2 1 1 0 0.9954 18 0 0 0 0.00E+00 1.96E+07 - - - 8.5135 1 221125_WJC_METTL3_EV_vs_WT_F08.24472.24472.2 3.93E-05 16/34 A.ASDVDLEIESLLNQQSTK[136.11].E "sp|Q86U44|MTA70_HUMAN,tr|F5H6D8|F5H6D8_HUMAN,tr|H0YFV6|H0YFV6_HUMAN,tr|B4DTN4|B4DTN4_HUMAN" 4 1997.0044 0.91 124017 24472 2 1997.991217 999.5095 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 3.92 3912.6 - 225817 - - - 494.1336 - 3.501 0.597 - 1067.8 1 1 0 0.9868 18 0 0 0 3.33E+06 3.67E+06 - - - 6.2213 1 221125_WJC_METTL3_EV_vs_WT_F08.24490.24490.4 1.56E-10 27/168 R.R[166.11]AEQDSTTVAAFASSLVSGLNSSASEPAK[136.11].E "sp|Q86U44|MTA70_HUMAN,tr|F5H6D8|F5H6D8_HUMAN,tr|H0YFV6|H0YFV6_HUMAN,tr|B4DTN4|B4DTN4_HUMAN" 4 2898.4326 0.01 124024 24490 4 2898.427352 725.6154 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 4.68 3915.1 - 3.59E+06 - - - -1.8037 - 4.907 0.606 - 432.5 1 2 0 -0.0052 29 0 0 0 2.74E+06 4.97E+08 - - - 4.9894 1 221125_WJC_METTL3_EV_vs_WT_F08.24491.24491.3 3.74E-11 23/124 R.R[166.11]AEQDSTTVAAFASSLVSGLNSSASEPAK[136.11]EPA.K "sp|Q86U44|MTA70_HUMAN,tr|F5H6D8|F5H6D8_HUMAN,tr|H0YFV6|H0YFV6_HUMAN,tr|B4DTN4|B4DTN4_HUMAN" 4 3195.5651 2.52 124025 24491 3 3196.556595 1066.1956 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 4.41 3915.3 - 548041 - - - 310.2878 - 4.342 0.649 - 403.1 1 1 1 0.9915 32 0 0 0 7.35E+07 2.92E+07 - - - 8.8792 1 221125_WJC_METTL3_EV_vs_WT_F08.24494.24494.4 1.01E-12 24/240 R.NPGEQASNTNGTHQFSPAGLSQDFFSSSLASPSLPLASTGK.F "sp|P39880|CUX1_HUMAN,tr|A0A2R8Y852|A0A2R8Y852_HUMAN" 2 4133.9566 0.74 124026 24494 4 4133.945313 1034.4964 Homeobox protein cut-like 1 OS=Homo sapiens OX=9606 GN=CUX1 PE=1 SV=3 5.32 3915.7 - 649886 - - - -2.7414 - 4.522 0.75 - 173.5 1 2 0 -0.0113 41 0 0 0 2.35E+07 3.20E+07 - - - 6.1843 1 221125_WJC_METTL3_EV_vs_WT_F08.24502.24502.4 6.11E-13 25/240 R.NPGEQASNTNGTHQFSPAGLSQDFFSSSLASPSLPLASTGK[136.11].F "sp|P39880|CUX1_HUMAN,tr|A0A2R8Y852|A0A2R8Y852_HUMAN" 2 4141.9708 0.73 124030 24502 4 4141.962782 1036.5 Homeobox protein cut-like 1 OS=Homo sapiens OX=9606 GN=CUX1 PE=1 SV=3 5.32 3916.8 - 605835 - - - -1.9469 - 3.637 0.779 - 229.9 1 2 0 -0.0081 41 0 0 0 2.34E+07 3.19E+07 - - - 6.3751 0.9896 221125_WJC_METTL3_EV_vs_WT_F08.24507.24507.3 0.000891 7/128 R.SDSPVPTAPTSGGPK[136.11]PSTASAVPELATDPELEK[136.11].K "sp|Q86U44|MTA70_HUMAN,tr|B4E349|B4E349_HUMAN,tr|F5H6D8|F5H6D8_HUMAN,tr|B4DTN4|B4DTN4_HUMAN" 4 3248.6271 0.03 124033 24507 3 3249.628389 1083.883 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 4.18 3917.4 - 124873 - - - 308.2197 - 1.409 0.442 - 24.3 1 2 0 1.0013 33 0 0 0 7.89E+04 2.93E+06 - - - 3.9793 0.9999 221125_WJC_METTL3_EV_vs_WT_F08.24509.24509.3 0.00348 Aug-56 R.STSHK[136.11]PDEIYGMIER[166.11].L sp|Q86U44|MTA70_HUMAN 1 1779.8581 0.03 124034 24509 3 1779.855799 594.2933 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 5.42 3917.7 - 112960 - - - -1.267 - 1.764 0.482 - 83.1 1 2 0 -0.0023 15 0 0 0 5.45E+05 1.86E+07 - - - 5.3942 1 221125_WJC_METTL3_EV_vs_WT_F08.24511.24511.3 6.47E-09 11/160 R.NPGEQASNTNGTHQFSPAGLSQDFFSSSLASPSLPLASTGK.F "sp|P39880|CUX1_HUMAN,tr|A0A2R8Y852|A0A2R8Y852_HUMAN" 2 4133.9566 3.52 124035 24511 3 4133.948482 1378.9928 Homeobox protein cut-like 1 OS=Homo sapiens OX=9606 GN=CUX1 PE=1 SV=3 5.32 3918 - 135193 - - - -1.9749 - 2.73 0.748 - 46.4 1 2 0 -0.0082 41 0 0 0 2.45E+06 6.94E+05 - - - 9.1877 0.7803 221125_WJC_METTL3_EV_vs_WT_F08.24518.24518.4 1.16E-10 20/174 R.R[166.11]AEQDSTTVAAFASSLVSGLNSSASEPAK[136.11]E.P "sp|Q86U44|MTA70_HUMAN,tr|F5H6D8|F5H6D8_HUMAN,tr|H0YFV6|H0YFV6_HUMAN,tr|B4DTN4|B4DTN4_HUMAN" 4 3027.4752 0.02 124039 24518 4 3028.466809 757.8761 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 4.62 3919 - 331790 - - - 327.5455 - 4.173 0.649 - 234.9 1 1 0 0.9916 30 0 0 0 3.72E+04 1.93E+06 - - - 5.0374 0.9909 221125_WJC_METTL3_EV_vs_WT_F08.24528.24528.3 6.10E-07 15/104 K.R[166.11]R[166.11]AEQDSTTVAAFASSLVSGLNSSASE.P "sp|Q86U44|MTA70_HUMAN,tr|F5H6D8|F5H6D8_HUMAN,tr|H0YFV6|H0YFV6_HUMAN,tr|B4DTN4|B4DTN4_HUMAN" 4 2760.3429 0.13 124044 24528 3 2760.338109 921.1216 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 4.94 3920.2 - 433635 - - - -1.7429 - 3.567 0.571 - 219.9 1 1 1 -0.0048 27 0 0 0 4.49E+05 3.49E+06 - - - 7.8305 0.9645 221125_WJC_METTL3_EV_vs_WT_F08.24529.24529.4 0.000962 15/150 R.KDGNASGTTLLEALDC[160.03]ILPPTRPTDK.P "sp|P68104|EF1A1_HUMAN,sp|Q5VTE0|EF1A3_HUMAN,tr|A0A7I2V659|A0A7I2V659_HUMAN,tr|A0A7I2V3H3|A0A7I2V3H3_HUMAN,tr|A0A7I2V5N4|A0A7I2V5N4_HUMAN,tr|A0A087WVQ9|A0A087WVQ9_HUMAN,tr|A0A087WV01|A0A087WV01_HUMAN" 7 2782.4171 0.19 124045 24529 4 2782.406995 696.6116 Elongation factor 1-alpha 1 OS=Homo sapiens OX=9606 GN=EEF1A1 PE=1 SV=1 4.68 3920.3 - 292695 - - - -3.635 - 2.724 0.453 - 84.8 1 1 0 -0.0101 26 0 0 0 4.57E+06 2.36E+07 - - - 3.4822 1 221125_WJC_METTL3_EV_vs_WT_F08.24532.24532.4 4.83E-11 24/150 R.K[136.11]DGNASGTTLLEALDC[160.03]ILPPTR[166.11]PTDK[136.11].P "sp|P68104|EF1A1_HUMAN,sp|Q5VTE0|EF1A3_HUMAN,tr|A0A7I2V659|A0A7I2V659_HUMAN,tr|A0A7I2V3H3|A0A7I2V3H3_HUMAN,tr|A0A7I2V5N4|A0A7I2V5N4_HUMAN,tr|A0A087WVQ9|A0A087WVQ9_HUMAN,tr|A0A087WV01|A0A087WV01_HUMAN" 7 2808.4538 0.19 124046 24532 4 2808.44252 703.1207 Elongation factor 1-alpha 1 OS=Homo sapiens OX=9606 GN=EEF1A1 PE=1 SV=1 4.68 3920.7 - 1.23E+06 - - - -4.009 - 3.804 0.628 - 209.6 1 1 0 -0.0113 26 0 0 0 4.57E+06 2.36E+07 - - - 5.1104 1 221125_WJC_METTL3_EV_vs_WT_F08.24537.24537.3 7.35E-16 26/112 R.R[166.11]AEQDSTTVAAFASSLVSGLNSSASEPAK[136.11].E "sp|Q86U44|MTA70_HUMAN,tr|F5H6D8|F5H6D8_HUMAN,tr|H0YFV6|H0YFV6_HUMAN,tr|B4DTN4|B4DTN4_HUMAN" 4 2898.4326 0.01 124048 24537 3 2898.415872 967.1515 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 4.68 3921.4 - 1.65E+06 - - - -5.7645 - 4.897 0.715 - 535.6 1 2 0 -0.0167 29 0 0 0 1.71E+07 3.28E+09 - - - 10.1618 0.9906 221125_WJC_METTL3_EV_vs_WT_F08.24577.24577.3 7.69E-07 16/96 K.R[166.11]R[166.11]AEQDSTTVAAFASSLVSGLNSSA.S "sp|Q86U44|MTA70_HUMAN,tr|F5H6D8|F5H6D8_HUMAN,tr|H0YFV6|H0YFV6_HUMAN,tr|B4DTN4|B4DTN4_HUMAN" 4 2544.2683 0.07 124052 24577 3 2544.263719 849.0967 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 6.07 3928 - 1.11E+06 - - - -1.7997 - 3.576 0.571 - 272.1 1 1 1 -0.0046 25 0 0 0 1.58E+06 2.31E+07 - - - 7.8364 0.9999 221125_WJC_METTL3_EV_vs_WT_F08.24596.24596.2 4.05E-07 22-Nov K.VDLLNQEIEFLK.V sp|P35908|K22E_HUMAN 1 1459.7922 999 124062 24596 2 1459.791551 730.9034 "Keratin, type II cytoskeletal 2 epidermal OS=Homo sapiens OX=9606 GN=KRT2 PE=1 SV=2" 4.14 3930.5 - 186697 - - - -0.4761 - 2.475 0.514 - 616.6 1 2 0 -0.0007 12 0 0 0 3.28E+06 0.00E+00 - - - 5.2217 0.9996 221125_WJC_METTL3_EV_vs_WT_F08.24611.24611.3 0.00163 Jun-52 K.K[136.11]GPGEVAGTVTGQK[136.11].R "sp|Q86U44|MTA70_HUMAN,tr|F5H6D8|F5H6D8_HUMAN,tr|H0YFV6|H0YFV6_HUMAN,tr|B4DTN4|B4DTN4_HUMAN" 4 1343.738 0.001 124070 24611 3 1343.737855 448.9199 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 8.59 3932.7 - 94551 - - - -0.0923 - 1.496 0.386 - 51.4 1 2 0 -0.0001 14 0 0 0 0.00E+00 3.13E+06 - - - 3.9139 1 221125_WJC_METTL3_EV_vs_WT_F08.24639.24639.4 1.99E-08 23/120 R.K[136.11]HAASDVDLEIESLLNQQSTK[136.11].E "sp|Q86U44|MTA70_HUMAN,tr|F5H6D8|F5H6D8_HUMAN,tr|H0YFV6|H0YFV6_HUMAN,tr|B4DTN4|B4DTN4_HUMAN" 4 2341.2096 0.13 124087 24639 4 2341.210017 586.3097 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 4.75 3936.6 - 575437 - - - 0.17 - 4.017 0.535 - 471.8 1 2 0 0.0004 21 0 0 0 6.07E+06 4.64E+07 - - - 4.3423 0.9567 221125_WJC_METTL3_EV_vs_WT_F08.24643.24643.3 5.31E-07 18/72 H.AASDVDLEIESLLNQQSTK[136.11].E "sp|Q86U44|MTA70_HUMAN,tr|F5H6D8|F5H6D8_HUMAN,tr|H0YFV6|H0YFV6_HUMAN,tr|B4DTN4|B4DTN4_HUMAN" 4 2068.0415 0.04 124089 24643 3 2069.041902 690.3545 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 3.92 3937.1 - 381494 - - - 483.7224 - 3.609 0.586 - 469.5 1 1 0 1.0004 19 0 0 0 4.30E+05 1.22E+07 - - - 7.9494 1 221125_WJC_METTL3_EV_vs_WT_F08.24650.24650.4 4.25E-11 21/186 R.AEQDSTTVAAFASSLVSGLNSSASEPAK[136.11]EPAK[136.11].K "sp|Q86U44|MTA70_HUMAN,tr|F5H6D8|F5H6D8_HUMAN,tr|H0YFV6|H0YFV6_HUMAN,tr|B4DTN4|B4DTN4_HUMAN" 4 3165.5648 0.01 124094 24650 4 3166.560185 792.3985 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 4.41 3938.1 - 326230 - - - 314.4314 - 4.365 0.673 - 223.2 1 2 1 0.9954 32 0 0 0 6.73E+04 6.27E+06 - - - 5.253 0.9978 221125_WJC_METTL3_EV_vs_WT_F08.24654.24654.4 9.79E-10 15/198 K.DHTPSQELALTQSVGGDSSADR[166.11]LFPPQWIC[160.03]C[160.03]DIR[166.11].Y sp|Q86U44|MTA70_HUMAN 1 3875.811 0.16 124096 24654 4 3876.810385 969.96 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 4.35 3938.6 - 144930 - - - 257.8487 - 2.966 0.586 - 76.5 1 2 1 0.9994 34 0 0 0 1.13E+06 7.25E+06 - - - 4.3739 0.986 221125_WJC_METTL3_EV_vs_WT_F08.24671.24671.4 0.0333 14/84 R.STSHK[136.11]PDEIYGMIER[166.11].L sp|Q86U44|MTA70_HUMAN 1 1779.8581 0 124102 24671 4 1779.866271 445.9718 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 5.42 3941.1 - 0 - - - 4.6167 - 1.998 0.281 - 97 1 2 0 0.0082 15 0 0 0 1.71E+04 4.61E+06 - - - 1.9172 1 221125_WJC_METTL3_EV_vs_WT_F08.24680.24680.4 5.45E-25 51/222 K.GILGYTEHQVVSSDFNSDTHSSTFDAGAGIALNDHFVK.L "sp|P04406|G3P_HUMAN,tr|E7EUT5|E7EUT5_HUMAN" 2 4035.8875 0.81 124105 24680 4 4035.91668 1009.9792 Glyceraldehyde-3-phosphate dehydrogenase OS=Homo sapiens OX=9606 GN=GAPDH PE=1 SV=3 4.7 3942.5 - 3.44E+06 - - - 7.2291 - 7.403 0.746 - 1012.2 1 2 0 0.0292 38 0 0 0 1.98E+07 2.44E+07 - - - 6.2949 0.9998 221125_WJC_METTL3_EV_vs_WT_F08.24689.24689.4 1.19E-10 29/102 R.SPSELFAQHIVTIVHHVK.E "sp|Q9Y2W1|TR150_HUMAN,tr|A0A3B3ITZ9|A0A3B3ITZ9_HUMAN" 2 2041.1109 2.82 124111 24689 4 2041.12076 511.285 Thyroid hormone receptor-associated protein 3 OS=Homo sapiens OX=9606 GN=THRAP3 PE=1 SV=2 6.78 3943.6 - 1.87E+06 - - - 4.8332 - 4.259 0.602 - 706.8 1 2 0 0.0099 18 0 0 0 5.30E+06 1.88E+06 - - - 4.9595 0.9999 221125_WJC_METTL3_EV_vs_WT_F08.24693.24693.4 1.41E-11 24/102 R.SPSELFAQHIVTIVHHVK[136.11].E "sp|Q9Y2W1|TR150_HUMAN,tr|A0A3B3ITZ9|A0A3B3ITZ9_HUMAN" 2 2049.1251 2.82 124115 24693 4 2049.133555 513.2886 Thyroid hormone receptor-associated protein 3 OS=Homo sapiens OX=9606 GN=THRAP3 PE=1 SV=2 6.78 3944.1 - 612851 - - - 4.1286 - 3.882 0.607 - 456.6 1 2 0 0.0085 18 0 0 0 5.30E+06 1.88E+06 - - - 4.9716 0.9985 221125_WJC_METTL3_EV_vs_WT_F08.24701.24701.4 4.26E-08 20/132 R.KTSQLLETLNQLSTHTHVVDITR.T "sp|Q14203|DCTN1_HUMAN,tr|A0A804CDA6|A0A804CDA6_HUMAN,tr|E7EX90|E7EX90_HUMAN,tr|A0A7P0Z4C3|A0A7P0Z4C3_HUMAN,tr|E7EWF7|E7EWF7_HUMAN" 5 2633.4137 2.25 124118 24701 4 2633.430901 659.3607 Dynactin subunit 1 OS=Homo sapiens OX=9606 GN=DCTN1 PE=1 SV=3 6.92 3945.2 - 663214 - - - 6.5398 - 4.365 0.47 - 309.6 1 2 0 0.0172 23 0 0 0 3.41E+06 1.52E+06 - - - 3.7895 0.9984 221125_WJC_METTL3_EV_vs_WT_F08.24703.24703.4 4.54E-07 23/204 K.QSKPVTTPEEIAQVATISANGDKEIGNIISDAMK[136.11]K[136.11].V "sp|P10809|CH60_HUMAN,tr|A0A7I2V599|A0A7I2V599_HUMAN,tr|E7EXB4|E7EXB4_HUMAN,tr|A0A7I2YQ71|A0A7I2YQ71_HUMAN,tr|E7ESH4|E7ESH4_HUMAN,tr|A0A7I2V5M1|A0A7I2V5M1_HUMAN,tr|A0A7I2V5K3|A0A7I2V5K3_HUMAN,tr|A0A7I2V369|A0A7I2V369_HUMAN" 8 3698.9372 - 124120 24703 4 3698.919342 925.7416 "60 kDa heat shock protein, mitochondrial OS=Homo sapiens OX=9606 GN=HSPD1 PE=1 SV=2" 4.94 3945.5 - 1.31E+06 - - - -4.816 - 4.758 0.484 - 172.2 1 2 1 -0.0178 35 0 0 0 - - - - - 3.8962 0.9933 221125_WJC_METTL3_EV_vs_WT_F08.24714.24714.3 0.000209 23/80 R.K[136.11]HAASDVDLEIESLLNQQSTK[136.11].E "sp|Q86U44|MTA70_HUMAN,tr|F5H6D8|F5H6D8_HUMAN,tr|H0YFV6|H0YFV6_HUMAN,tr|B4DTN4|B4DTN4_HUMAN" 4 2341.2096 0 124126 24714 3 2342.202405 781.4105 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 4.75 3946.9 - 1.18E+06 - - - 424.0483 - 3.421 0.521 - 424.1 1 2 0 0.9928 21 0 0 0 1.27E+05 6.10E+07 - - - 7.0223 0.9736 221125_WJC_METTL3_EV_vs_WT_F08.24721.24721.4 3.67E-05 14/102 R.K[136.11]IELFGR[166.11]PHNVQPNWITL.G sp|Q86U44|MTA70_HUMAN 1 2179.2021 0.13 124129 24721 4 2179.201586 545.8078 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 8.75 3947.8 - 543047 - - - -0.2418 - 2.992 0.361 - 102.4 1 1 0 -0.0005 18 0 0 0 4.20E+05 3.17E+06 - - - 2.7434 0.9874 221125_WJC_METTL3_EV_vs_WT_F08.24722.24722.4 4.95E-06 16/120 S.LHTDGDKAFVDFLSDEIKEER.K sp|Q07021|C1QBP_HUMAN 1 2463.1918 1.53 124130 24722 4 2463.191578 616.8052 "Complement component 1 Q subcomponent-binding protein, mitochondrial OS=Homo sapiens OX=9606 GN=C1QBP PE=1 SV=1" 4.38 3947.9 - 648499 - - - -0.0836 - 2.97 0.524 - 206.3 1 1 2 -0.0002 21 0 0 0 7.31E+06 4.78E+06 - - - 4.1468 0.9998 221125_WJC_METTL3_EV_vs_WT_F08.24728.24728.4 9.59E-05 15/240 R.DATWSPLNHSLLTTVGWDHQVVHHVVPTEPLPAPGPASVTE.- "sp|Q9BQA1|MEP50_HUMAN,tr|H0Y711|H0Y711_HUMAN" 2 4391.1975 - 124134 24728 4 4391.192157 1098.8066 Methylosome protein 50 OS=Homo sapiens OX=9606 GN=WDR77 PE=1 SV=1 5.25 3948.6 - 739027 - - - -1.2133 - 2.625 0.367 - 43.6 1 2 0 -0.0053 41 0 0 0 - - - - - 2.6961 1 221125_WJC_METTL3_EV_vs_WT_F08.24731.24731.4 9.42E-10 26/150 R.SFGTEDRPTDRPIPPRDEVFEYIIFR.G "sp|Q8ND56|LS14A_HUMAN,tr|I3L4Q1|I3L4Q1_HUMAN,tr|A0A140TA76|A0A140TA76_HUMAN,tr|K7EMZ9|K7EMZ9_HUMAN" 4 3151.5727 1.08 124135 24731 4 3151.569785 788.9005 Protein LSM14 homolog A OS=Homo sapiens OX=9606 GN=LSM14A PE=1 SV=3 4.59 3949 - 6.09E+06 - - - -0.9246 - 2.776 0.643 - 115.7 1 2 1 -0.0029 26 0 0 0 6.08E+07 5.62E+07 - - - 5.1439 0.9999 221125_WJC_METTL3_EV_vs_WT_F08.24743.24743.4 6.72E-09 19/162 R.VAIEHLDK[136.11]ISDSVLVDIK[136.11]DTEPLIQTAK[136.11].T "sp|P48643|TCPE_HUMAN,tr|E9PCA1|E9PCA1_HUMAN,tr|B7ZAR1|B7ZAR1_HUMAN,tr|E7ENZ3|E7ENZ3_HUMAN" 4 3113.7286 0.82 124141 24743 4 3113.724098 779.4394 T-complex protein 1 subunit epsilon OS=Homo sapiens OX=9606 GN=CCT5 PE=1 SV=1 4.52 3950.5 - 486518 - - - -1.4449 - 3.531 0.608 - 136 1 2 2 -0.0045 28 0 0 0 1.71E+06 2.08E+06 - - - 4.9085 1 221125_WJC_METTL3_EV_vs_WT_F08.24768.24768.4 3.68E-11 22/102 K.STSESFIQHIVSLVHHVK.E "sp|Q9NYF8|BCLF1_HUMAN,tr|E9PKI6|E9PKI6_HUMAN,tr|A0A1W2PQ43|A0A1W2PQ43_HUMAN,tr|E9PK91|E9PK91_HUMAN,tr|E9PJA7|E9PJA7_HUMAN,tr|E9PK09|E9PK09_HUMAN,tr|E9PQN2|E9PQN2_HUMAN" 7 2047.0851 2.01 124154 24768 4 2047.081017 512.7785 Bcl-2-associated transcription factor 1 OS=Homo sapiens OX=9606 GN=BCLAF1 PE=1 SV=2 6.78 3953.8 - 1.49E+06 - - - -1.9818 - 3.477 0.64 - 300.6 1 2 0 -0.0041 18 0 0 0 3.86E+07 1.92E+07 - - - 5.2223 1 221125_WJC_METTL3_EV_vs_WT_F08.24772.24772.4 1.75E-13 24/102 K.STSESFIQHIVSLVHHVK[136.11].E "sp|Q9NYF8|BCLF1_HUMAN,tr|E9PKI6|E9PKI6_HUMAN,tr|A0A1W2PQ43|A0A1W2PQ43_HUMAN,tr|E9PK91|E9PK91_HUMAN,tr|E9PJA7|E9PJA7_HUMAN,tr|E9PK09|E9PK09_HUMAN,tr|E9PQN2|E9PQN2_HUMAN" 7 2055.0993 2.01 124155 24772 4 2055.094951 514.7821 Bcl-2-associated transcription factor 1 OS=Homo sapiens OX=9606 GN=BCLAF1 PE=1 SV=2 6.78 3954.4 - 2.59E+06 - - - -2.1035 - 3.756 0.686 - 406.8 1 2 0 -0.0043 18 0 0 0 3.86E+07 1.92E+07 - - - 5.6491 1 221125_WJC_METTL3_EV_vs_WT_F08.24777.24777.3 2.61E-09 17/68 K.STSESFIQHIVSLVHHVK[136.11].E "sp|Q9NYF8|BCLF1_HUMAN,tr|E9PKI6|E9PKI6_HUMAN,tr|A0A1W2PQ43|A0A1W2PQ43_HUMAN,tr|E9PK91|E9PK91_HUMAN,tr|E9PJA7|E9PJA7_HUMAN,tr|E9PK09|E9PK09_HUMAN,tr|E9PQN2|E9PQN2_HUMAN" 7 2055.0993 1.53 124158 24777 3 2055.097048 686.0404 Bcl-2-associated transcription factor 1 OS=Homo sapiens OX=9606 GN=BCLAF1 PE=1 SV=2 6.78 3955 - 940216 - - - -1.0832 - 3.123 0.629 - 372.6 1 2 0 -0.0022 18 0 0 0 1.23E+07 8.05E+06 - - - 8.3878 0.8757 221125_WJC_METTL3_EV_vs_WT_F08.24778.24778.4 0.682 7/168 K.EKNYEWSFIQC[160.03]PAC[160.03]TC[160.03]SGHANIC[160.03]HLHTGK[136.11].C tr|H0YDQ9|H0YDQ9_HUMAN 1 3512.5362 - 124159 24778 4 3512.54589 879.1413 Attractin-like protein 1 (Fragment) OS=Homo sapiens OX=9606 GN=ATRNL1 PE=4 SV=1 7.06 3955.1 - 364788 - - - 2.753 - 1.276 0.203 - 14.5 1 2 1 0.0097 29 0 0 0 - - - - - 1.0653 0.9961 221125_WJC_METTL3_EV_vs_WT_F08.24779.24779.3 5.63E-09 13/60 T.SESFIQHIVSLVHHVK.E "sp|Q9NYF8|BCLF1_HUMAN,tr|E9PKI6|E9PKI6_HUMAN,tr|A0A1W2PQ43|A0A1W2PQ43_HUMAN,tr|E9PK91|E9PK91_HUMAN,tr|E9PJA7|E9PJA7_HUMAN,tr|E9PK09|E9PK09_HUMAN,tr|E9PQN2|E9PQN2_HUMAN" 7 1859.0054 0.54 124160 24779 3 1859.002044 620.6757 Bcl-2-associated transcription factor 1 OS=Homo sapiens OX=9606 GN=BCLAF1 PE=1 SV=2 6.78 3955.3 - 148128 - - - -1.7875 - 2.663 0.517 - 151.2 1 1 0 -0.0033 16 0 0 0 7.82E+05 1.45E+06 - - - 6.8163 1 221125_WJC_METTL3_EV_vs_WT_F08.24786.24786.3 2.70E-05 Aug-56 R.STSHK[136.11]PDEIYGMIER[166.11].L sp|Q86U44|MTA70_HUMAN 1 1779.8581 0.34 124165 24786 3 1779.8568 594.2933 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 5.42 3956.2 - 96653.1 - - - -0.7046 - 1.628 0.552 - 73.2 1 2 0 -0.0013 15 0 0 0 3.06E+06 9.09E+06 - - - 5.9656 0.996 221125_WJC_METTL3_EV_vs_WT_F08.24787.24787.4 1.66E-08 15/96 T.RTHNLEPYFESFINNLR.R sp|P04264|K2C1_HUMAN 1 2149.0705 10.69 124166 24787 4 2149.07037 538.2749 "Keratin, type II cytoskeletal 1 OS=Homo sapiens OX=9606 GN=KRT1 PE=1 SV=6" 6.76 3956.3 - 90880.3 - - - -0.0544 - 2.535 0.506 - 219.7 1 1 0 -0.0001 17 0 0 0 1.44E+06 1.34E+05 - - - 3.9532 1 221125_WJC_METTL3_EV_vs_WT_F08.24802.24802.3 2.32E-13 18/60 R.THNLEPYFESFINNLR.R sp|P04264|K2C1_HUMAN 1 1992.9694 17.68 124177 24802 3 1992.977893 665.3304 "Keratin, type II cytoskeletal 1 OS=Homo sapiens OX=9606 GN=KRT1 PE=1 SV=6" 5.37 3958.4 - 334255 - - - 4.2735 - 3.612 0.709 - 639 1 2 0 0.0085 16 0 0 0 8.49E+06 4.80E+05 - - - 9.7375 0.9929 221125_WJC_METTL3_EV_vs_WT_F08.24803.24803.4 0.041 6/108 R.GLLQDDAHPTLVTYADHSK[136.11].L "sp|Q86U44|MTA70_HUMAN,tr|F5H6D8|F5H6D8_HUMAN,tr|H0YFV6|H0YFV6_HUMAN,tr|B4DTN4|B4DTN4_HUMAN" 4 2088.0367 0.02 124178 24803 4 2088.047168 523.0165 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 5.13 3958.6 - 82318.9 - - - 4.9975 - 1.199 0.35 - 8.4 1 2 0 0.0104 19 0 0 0 6.98E+04 2.98E+06 - - - 2.3309 0.9962 221125_WJC_METTL3_EV_vs_WT_F08.24804.24804.3 1.15E-07 11/124 R.AEQDSTTVAAFASSLVSGLNSSASEPAK[136.11]EPAK[136.11].K "sp|Q86U44|MTA70_HUMAN,tr|F5H6D8|F5H6D8_HUMAN,tr|H0YFV6|H0YFV6_HUMAN,tr|B4DTN4|B4DTN4_HUMAN" 4 3165.5648 0.01 124179 24804 3 3166.565255 1056.1956 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 4.41 3958.7 - 129765 - - - 316.033 - 2.523 0.55 - 72.3 1 2 1 1.0004 32 0 0 0 1.54E+05 2.98E+07 - - - 6.524 0.9999 221125_WJC_METTL3_EV_vs_WT_F08.24845.24845.2 0.00132 22-Oct R.NLDLDSIIAEVK.A "sp|P48668|K2C6C_HUMAN,sp|P04259|K2C6B_HUMAN,sp|P13647|K2C5_HUMAN,sp|P35908|K22E_HUMAN,sp|O95678|K2C75_HUMAN,sp|Q5XKE5|K2C79_HUMAN,sp|P02538|K2C6A_HUMAN,tr|H0YI76|H0YI76_HUMAN,tr|H0YIN9|H0YIN9_HUMAN" 9 1328.7187 6.9 124205 24845 2 1328.717992 665.3666 "Keratin, type II cytoskeletal 6C OS=Homo sapiens OX=9606 GN=KRT6C PE=1 SV=3" 4.03 3964.3 - 585836 - - - -0.5682 - 2.226 0.494 - 234.6 1 2 0 -0.0008 12 0 0 0 1.17E+07 1.69E+06 - - - 4.7949 0.9999 221125_WJC_METTL3_EV_vs_WT_F08.24853.24853.2 0.000604 13/22 R.SLDLDSIIAEVK.A sp|P04264|K2C1_HUMAN 1 1301.7078 999 124208 24853 2 1301.707447 651.8612 "Keratin, type II cytoskeletal 1 OS=Homo sapiens OX=9606 GN=KRT1 PE=1 SV=6" 4.03 3965.3 - 487671 - - - -0.3081 - 2.709 0.486 - 448.2 1 2 0 -0.0004 12 0 0 0 1.03E+07 0.00E+00 - - - 5.2526 0.9386 221125_WJC_METTL3_EV_vs_WT_F08.24861.24861.4 2.09E-09 14/198 K.QSK[136.11]PVTTPEEIAQVATISANGDK[136.11]EIGNIISDAMK[136.11].K "sp|P10809|CH60_HUMAN,tr|A0A7I2V599|A0A7I2V599_HUMAN,tr|E7EXB4|E7EXB4_HUMAN,tr|A0A7I2YQ71|A0A7I2YQ71_HUMAN,tr|E7ESH4|E7ESH4_HUMAN,tr|A0A7I2V5M1|A0A7I2V5M1_HUMAN,tr|A0A7I2V5K3|A0A7I2V5K3_HUMAN,tr|A0A7I2V369|A0A7I2V369_HUMAN" 8 3578.8564 4.11 124212 24861 4 3579.842228 895.7214 "60 kDa heat shock protein, mitochondrial OS=Homo sapiens OX=9606 GN=HSPD1 PE=1 SV=2" 4.51 3966.4 - 323311 - - - 275.4609 - 3.325 0.512 - 85.2 1 2 1 0.9858 34 0 0 0 3.21E+06 7.81E+05 - - - 3.7677 0.992 221125_WJC_METTL3_EV_vs_WT_F08.24870.24870.3 0.0629 Jul-44 R.SLDLDSIIAEVK.A sp|P04264|K2C1_HUMAN 1 1301.7078 999 124219 24870 3 1301.70863 434.9099 "Keratin, type II cytoskeletal 1 OS=Homo sapiens OX=9606 GN=KRT1 PE=1 SV=6" 4.03 3967.6 - 74403.4 - - - 0.6007 - 1.099 0.282 - 57.2 1 2 0 0.0008 12 0 0 0 6.62E+05 0.00E+00 - - - 1.9455 0.9255 221125_WJC_METTL3_EV_vs_WT_F08.24875.24875.3 1.37E-06 Nov-80 K.R[166.11]R[166.11]AEQDSTTVAAFASSLVSGL.N "sp|Q86U44|MTA70_HUMAN,tr|F5H6D8|F5H6D8_HUMAN,tr|H0YFV6|H0YFV6_HUMAN,tr|B4DTN4|B4DTN4_HUMAN" 4 2185.1242 0.001 124222 24875 3 2185.128477 729.382 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 6.07 3968.3 - 134934 - - - 1.9573 - 2.308 0.428 - 137.1 1 1 1 0.0043 21 0 0 0 0.00E+00 2.60E+06 - - - 5.3158 0.9999 221125_WJC_METTL3_EV_vs_WT_F08.24877.24877.4 2.30E-06 15/120 R.K[136.11]HAASDVDLEIESLLNQQSTK[136.11].E "sp|Q86U44|MTA70_HUMAN,tr|F5H6D8|F5H6D8_HUMAN,tr|H0YFV6|H0YFV6_HUMAN,tr|B4DTN4|B4DTN4_HUMAN" 4 2341.2096 0.03 124224 24877 4 2341.214179 586.3097 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 4.75 3968.6 - 244024 - - - 1.9477 - 3.473 0.495 - 212.2 1 2 0 0.0046 21 0 0 0 2.94E+05 9.47E+06 - - - 3.9449 0.997 221125_WJC_METTL3_EV_vs_WT_F08.24882.24882.3 0.0197 Aug-52 K.K[136.11]GPGEVAGTVTGQK[136.11].R "sp|Q86U44|MTA70_HUMAN,tr|F5H6D8|F5H6D8_HUMAN,tr|H0YFV6|H0YFV6_HUMAN,tr|B4DTN4|B4DTN4_HUMAN" 4 1343.738 0.03 124226 24882 3 1343.741397 448.9199 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 8.59 3969.4 - 89433.5 - - - 2.5437 - 1.42 0.34 - 38.5 1 2 0 0.0034 14 0 0 0 1.17E+05 3.97E+06 - - - 3.2616 0.9999 221125_WJC_METTL3_EV_vs_WT_F08.24913.24913.2 2.13E-05 Aug-34 R.GDADQASNILASFGLSAR[166.11].D "sp|P43243|MATR3_HUMAN,tr|A8MXP9|A8MXP9_HUMAN,tr|D6R991|D6R991_HUMAN,tr|A0A0R4J2E8|A0A0R4J2E8_HUMAN,tr|D6REM6|D6REM6_HUMAN" 5 1801.8834 1.62 124242 24913 2 1801.884171 901.949 Matrin-3 OS=Homo sapiens OX=9606 GN=MATR3 PE=1 SV=2 4.21 3973.8 - 49998.2 - - - 0.4218 - 1.972 0.547 - 138.2 1 2 0 0.0008 18 0 0 0 1.05E+06 6.50E+05 - - - 4.7504 0.9552 221125_WJC_METTL3_EV_vs_WT_F08.24915.24915.3 0.0182 8/128 R.SDSPVPTAPTSGGPK[136.11]PSTASAVPELATDPELEK[136.11].K "sp|Q86U44|MTA70_HUMAN,tr|B4E349|B4E349_HUMAN,tr|F5H6D8|F5H6D8_HUMAN,tr|B4DTN4|B4DTN4_HUMAN" 4 3248.6271 0.001 124243 24915 3 3249.63948 1083.883 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 4.18 3974.1 - 70380.1 - - - 311.6338 - 1.525 0.413 - 30.5 1 2 0 1.0124 33 0 0 0 0.00E+00 5.37E+06 - - - 3.835 0.9751 221125_WJC_METTL3_EV_vs_WT_F08.24916.24916.3 0.0847 Apr-68 R.GDADQASNILASFGLSAR[166.11].D "sp|P43243|MATR3_HUMAN,tr|A8MXP9|A8MXP9_HUMAN,tr|D6R991|D6R991_HUMAN,tr|A0A0R4J2E8|A0A0R4J2E8_HUMAN,tr|D6REM6|D6REM6_HUMAN" 5 1801.8834 1.26 124244 24916 3 1801.886418 601.6351 Matrin-3 OS=Homo sapiens OX=9606 GN=MATR3 PE=1 SV=2 4.21 3974.2 - 78706.3 - - - 1.6688 - 1.123 0.262 - 14.2 3 2 0 0.003 18 0 0 0 1.09E+06 8.66E+05 - - - 1.5282 1 221125_WJC_METTL3_EV_vs_WT_F08.24917.24917.2 6.09E-11 Dec-34 R.GDADQASNILASFGLSAR.D "sp|P43243|MATR3_HUMAN,tr|A8MXP9|A8MXP9_HUMAN,tr|D6R991|D6R991_HUMAN,tr|A0A0R4J2E8|A0A0R4J2E8_HUMAN,tr|D6REM6|D6REM6_HUMAN" 5 1791.8751 1.62 124245 24917 2 1791.877038 896.9448 Matrin-3 OS=Homo sapiens OX=9606 GN=MATR3 PE=1 SV=2 4.21 3974.3 - 74658 - - - 1.0587 - 2.821 0.703 - 362.8 1 2 0 0.0019 18 0 0 0 1.05E+06 6.50E+05 - - - 6.7825 0.9962 221125_WJC_METTL3_EV_vs_WT_F08.24918.24918.3 7.93E-05 9/112 R.R[166.11]AEQDSTTVAAFASSLVSGLNSSASEPAK[136.11].E "sp|Q86U44|MTA70_HUMAN,tr|F5H6D8|F5H6D8_HUMAN,tr|H0YFV6|H0YFV6_HUMAN,tr|B4DTN4|B4DTN4_HUMAN" 4 2898.4326 0.001 124246 24918 3 2899.435396 967.1515 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 4.68 3974.4 - 73243.9 - - - 345.9856 - 2.137 0.428 - 62.5 1 2 0 1.0028 29 0 0 0 0.00E+00 3.32E+06 - - - 4.7811 1 221125_WJC_METTL3_EV_vs_WT_F08.24925.24925.4 0.000517 14/162 K.DGNASGTTLLEALDC[160.03]ILPPTR[166.11]PTDK[136.11]PLR[166.11].L "sp|P68104|EF1A1_HUMAN,sp|Q5VTE0|EF1A3_HUMAN,tr|A0A7I2V659|A0A7I2V659_HUMAN,tr|A0A7I2V3H3|A0A7I2V3H3_HUMAN,tr|A0A7I2V5N4|A0A7I2V5N4_HUMAN,tr|A0A087WVQ9|A0A087WVQ9_HUMAN,tr|A0A087WV01|A0A087WV01_HUMAN" 7 3048.5908 0.28 124251 24925 4 3048.596644 763.155 Elongation factor 1-alpha 1 OS=Homo sapiens OX=9606 GN=EEF1A1 PE=1 SV=1 4.68 3975.4 - 119708 - - - 1.9088 - 2.751 0.611 - 97.8 1 2 0 0.0058 28 0 0 0 1.25E+06 4.40E+06 - - - 4.8567 0.9966 221125_WJC_METTL3_EV_vs_WT_F08.24929.24929.3 0.0418 May-68 R.GDADQASNILASFGLSAR.D "sp|P43243|MATR3_HUMAN,tr|A8MXP9|A8MXP9_HUMAN,tr|D6R991|D6R991_HUMAN,tr|A0A0R4J2E8|A0A0R4J2E8_HUMAN,tr|D6REM6|D6REM6_HUMAN" 5 1791.8751 1.26 124253 24929 3 1791.879176 598.299 Matrin-3 OS=Homo sapiens OX=9606 GN=MATR3 PE=1 SV=2 4.21 3976 - 114710 - - - 2.2518 - 1.198 0.363 - 34.8 1 2 0 0.004 18 0 0 0 1.09E+06 8.66E+05 - - - 3.0358 0.9919 221125_WJC_METTL3_EV_vs_WT_F08.24931.24931.4 0.0413 6/144 R.RKLEGDSTDLSDQIAELQAQIAELK.M sp|P35579|MYH9_HUMAN 1 2770.4349 1.21 124255 24931 4 2770.443606 693.616 Myosin-9 OS=Homo sapiens OX=9606 GN=MYH9 PE=1 SV=4 4.3 3976.3 - 47761.6 - - - 3.154 - 1.412 0.339 - 14.3 1 2 1 0.0087 25 0 0 0 2.39E+05 1.99E+05 - - - 2.284 0.9547 221125_WJC_METTL3_EV_vs_WT_F08.24937.24937.3 1.33E-05 Sep-80 N.WITLGNQLDGIHLLDPDVVAR[166.11].F sp|Q86U44|MTA70_HUMAN 1 2354.2622 0 124259 24937 3 2354.267922 785.7613 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 4.41 3977.1 - 78923.9 - - - 2.4305 - 2.164 0.385 - 47.5 1 1 0 0.0057 21 0 0 0 4.72E+04 1.29E+07 - - - 4.6815 0.9999 221125_WJC_METTL3_EV_vs_WT_F08.24941.24941.4 6.45E-07 11/162 K.DGNASGTTLLEALDC[160.03]ILPPTRPTDKPLR.L "sp|P68104|EF1A1_HUMAN,sp|Q5VTE0|EF1A3_HUMAN,tr|A0A7I2V659|A0A7I2V659_HUMAN,tr|A0A7I2V3H3|A0A7I2V3H3_HUMAN,tr|A0A7I2V5N4|A0A7I2V5N4_HUMAN,tr|A0A087WVQ9|A0A087WVQ9_HUMAN,tr|A0A087WV01|A0A087WV01_HUMAN" 7 3020.5601 0.28 124261 24941 4 3020.56842 756.1473 Elongation factor 1-alpha 1 OS=Homo sapiens OX=9606 GN=EEF1A1 PE=1 SV=1 4.68 3977.7 - 200798 - - - 2.7594 - 2.512 0.554 - 56.6 1 2 0 0.0083 28 0 0 0 1.25E+06 4.40E+06 - - - 4.3317 0.9982 221125_WJC_METTL3_EV_vs_WT_F08.24955.24955.3 0.0845 Jul-80 R.K[136.11]HAASDVDLEIESLLNQQSTK[136.11].E "sp|Q86U44|MTA70_HUMAN,tr|F5H6D8|F5H6D8_HUMAN,tr|H0YFV6|H0YFV6_HUMAN,tr|B4DTN4|B4DTN4_HUMAN" 4 2341.2096 0.01 124270 24955 3 2341.21325 781.4105 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 4.75 3979.7 - 157096 - - - 1.5509 - 1.602 0.313 - 51.5 1 2 0 0.0036 21 0 0 0 3.62E+04 7.18E+06 - - - 3.1584 0.9999 221125_WJC_METTL3_EV_vs_WT_F08.24971.24971.4 4.57E-10 17/198 K.QSKPVTTPEEIAQVATISANGDKEIGNIISDAMK.K "sp|P10809|CH60_HUMAN,tr|A0A7I2V599|A0A7I2V599_HUMAN,tr|E7EXB4|E7EXB4_HUMAN,tr|A0A7I2YQ71|A0A7I2YQ71_HUMAN,tr|E7ESH4|E7ESH4_HUMAN,tr|A0A7I2V5M1|A0A7I2V5M1_HUMAN,tr|A0A7I2V5K3|A0A7I2V5K3_HUMAN,tr|A0A7I2V369|A0A7I2V369_HUMAN" 8 3554.8138 1.68 124280 24971 4 3554.816676 889.7107 "60 kDa heat shock protein, mitochondrial OS=Homo sapiens OX=9606 GN=HSPD1 PE=1 SV=2" 4.51 3981.8 - 163454 - - - 0.811 - 3.89 0.599 - 122.3 1 2 1 0.0029 34 0 0 0 3.82E+06 2.27E+06 - - - 4.844 1 221125_WJC_METTL3_EV_vs_WT_F08.24976.24976.3 2.87E-13 18/84 R.KPLVIIAEDVDGEALSTLVLNR.L "sp|P10809|CH60_HUMAN,tr|A0A7I2V2X6|A0A7I2V2X6_HUMAN,tr|A0A7I2YQK6|A0A7I2YQK6_HUMAN,tr|A0A7I2V599|A0A7I2V599_HUMAN,tr|A0A7I2YQ71|A0A7I2YQ71_HUMAN,tr|A0A7I2V5M1|A0A7I2V5M1_HUMAN,tr|A0A7I2V5K3|A0A7I2V5K3_HUMAN" 7 2364.3264 1.33 124283 24976 3 2364.329518 789.1161 "60 kDa heat shock protein, mitochondrial OS=Homo sapiens OX=9606 GN=HSPD1 PE=1 SV=2" 4.32 3982.4 - 258642 - - - 1.3073 - 3.68 0.708 - 300.2 1 2 0 0.0031 22 0 0 0 6.32E+06 4.74E+06 - - - 9.5216 1 221125_WJC_METTL3_EV_vs_WT_F08.24982.24982.3 9.51E-15 23/84 R.K[136.11]PLVIIAEDVDGEALSTLVLNR[166.11].L "sp|P10809|CH60_HUMAN,tr|A0A7I2V2X6|A0A7I2V2X6_HUMAN,tr|A0A7I2YQK6|A0A7I2YQK6_HUMAN,tr|A0A7I2V599|A0A7I2V599_HUMAN,tr|A0A7I2YQ71|A0A7I2YQ71_HUMAN,tr|A0A7I2V5M1|A0A7I2V5M1_HUMAN,tr|A0A7I2V5K3|A0A7I2V5K3_HUMAN" 7 2382.3489 1.33 124287 24982 3 2382.347181 795.1236 "60 kDa heat shock protein, mitochondrial OS=Homo sapiens OX=9606 GN=HSPD1 PE=1 SV=2" 4.32 3983.2 - 419243 - - - -0.7203 - 4.494 0.61 - 641.2 1 2 0 -0.0017 22 0 0 0 6.32E+06 4.74E+06 - - - 8.9032 1 221125_WJC_METTL3_EV_vs_WT_F08.24984.24984.4 9.39E-07 9/126 R.KPLVIIAEDVDGEALSTLVLNR.L "sp|P10809|CH60_HUMAN,tr|A0A7I2V2X6|A0A7I2V2X6_HUMAN,tr|A0A7I2YQK6|A0A7I2YQK6_HUMAN,tr|A0A7I2V599|A0A7I2V599_HUMAN,tr|A0A7I2YQ71|A0A7I2YQ71_HUMAN,tr|A0A7I2V5M1|A0A7I2V5M1_HUMAN,tr|A0A7I2V5K3|A0A7I2V5K3_HUMAN" 7 2364.3264 1.55 124288 24984 4 2364.323635 592.0889 "60 kDa heat shock protein, mitochondrial OS=Homo sapiens OX=9606 GN=HSPD1 PE=1 SV=2" 4.32 3983.5 - 94032.4 - - - -1.1809 - 2.02 0.532 - 56.9 1 2 0 -0.0028 22 0 0 0 8.04E+05 5.18E+05 - - - 4.0858 1 221125_WJC_METTL3_EV_vs_WT_F08.24986.24986.4 1.73E-06 11/126 R.K[136.11]PLVIIAEDVDGEALSTLVLNR[166.11].L "sp|P10809|CH60_HUMAN,tr|A0A7I2V2X6|A0A7I2V2X6_HUMAN,tr|A0A7I2YQK6|A0A7I2YQK6_HUMAN,tr|A0A7I2V599|A0A7I2V599_HUMAN,tr|A0A7I2YQ71|A0A7I2YQ71_HUMAN,tr|A0A7I2V5M1|A0A7I2V5M1_HUMAN,tr|A0A7I2V5K3|A0A7I2V5K3_HUMAN" 7 2382.3489 1.55 124290 24986 4 2382.346738 596.5945 "60 kDa heat shock protein, mitochondrial OS=Homo sapiens OX=9606 GN=HSPD1 PE=1 SV=2" 4.32 3983.7 - 71607.8 - - - -0.9062 - 2.294 0.583 - 109 1 2 0 -0.0022 22 0 0 0 8.04E+05 5.18E+05 - - - 4.5715 1 221125_WJC_METTL3_EV_vs_WT_F08.24990.24990.4 3.51E-06 9/162 R.HVDAHATLNDGVVVQVMGLLSNNNQALR.R "sp|Q13283|G3BP1_HUMAN,tr|A0A7I2YQB1|A0A7I2YQB1_HUMAN,tr|A0A7I2V5M7|A0A7I2V5M7_HUMAN,tr|E5RH42|E5RH42_HUMAN,tr|A0A7P0P2U7|A0A7P0P2U7_HUMAN,tr|A0A7I2YQU8|A0A7I2YQU8_HUMAN,tr|E5RJU8|E5RJU8_HUMAN,tr|A0A7I2V651|A0A7I2V651_HUMAN,tr|E5RIF8|E5RIF8_HUMAN,tr|A0A7I2YQN9|A0A7I2YQN9_HUMAN" 10 2984.525 1.63 124292 24990 4 2984.527501 747.1385 Ras GTPase-activating protein-binding protein 1 OS=Homo sapiens OX=9606 GN=G3BP1 PE=1 SV=1 5.98 3984.3 - 116216 - - - 0.8256 - 2.459 0.521 - 38.2 1 2 0 0.0025 28 0 0 0 7.53E+05 4.63E+05 - - - 4.0395 1 221125_WJC_METTL3_EV_vs_WT_F08.24993.24993.4 2.68E-06 12/162 R.HVDAHATLSDGVVVQVMGLLSNSGQPER.K "sp|Q9UN86|G3BP2_HUMAN,tr|A0A7I2V3E2|A0A7I2V3E2_HUMAN,tr|D6RAC7|D6RAC7_HUMAN,tr|D6RB17|D6RB17_HUMAN,tr|A0A7I2YQS2|A0A7I2YQS2_HUMAN,tr|A0A7I2YQG8|A0A7I2YQG8_HUMAN,tr|A0A7I2V572|A0A7I2V572_HUMAN,tr|D6RBW8|D6RBW8_HUMAN" 8 2915.456 1.63 124295 24993 4 2915.454424 729.8713 Ras GTPase-activating protein-binding protein 2 OS=Homo sapiens OX=9606 GN=G3BP2 PE=1 SV=2 5.21 3984.7 - 111554 - - - -0.5248 - 2.174 0.559 - 44.2 1 2 0 -0.0015 28 0 0 0 7.70E+05 4.71E+05 - - - 4.3322 0.9997 221125_WJC_METTL3_EV_vs_WT_F08.25004.25004.3 0.00328 Aug-56 R.STSHK[136.11]PDEIYGMIER[166.11].L sp|Q86U44|MTA70_HUMAN 1 1779.8581 0.03 124299 25004 3 1779.858544 594.2933 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 5.42 3986.4 - 112287 - - - 0.2753 - 1.572 0.413 - 77.6 1 2 0 0.0005 15 0 0 0 1.93E+05 6.32E+06 - - - 4.3247 0.9904 221125_WJC_METTL3_EV_vs_WT_F08.25060.25060.2 0.126 30-Apr K.AAGVNVEPFWPGLFAK.A sp|P05386|RLA1_HUMAN 1 1701.8879 1.8 124331 25060 2 1701.893321 851.9512 60S acidic ribosomal protein P1 OS=Homo sapiens OX=9606 GN=RPLP1 PE=1 SV=1 6.05 3994.1 - 42617.2 - - - 3.1982 - 0.958 0.397 - 40.3 1 2 0 0.0054 16 0 0 0 5.59E+05 3.10E+05 - - - 1.866 0.9978 221125_WJC_METTL3_EV_vs_WT_F08.25061.25061.2 0.0425 30-Apr K.AAGVNVEPFWPGLFAK[136.11].A sp|P05386|RLA1_HUMAN 1 1709.9021 1.8 124332 25061 2 1709.901801 855.9583 60S acidic ribosomal protein P1 OS=Homo sapiens OX=9606 GN=RPLP1 PE=1 SV=1 6.05 3994.2 - 23354.3 - - - -0.162 - 0.948 0.377 - 21.8 1 2 0 -0.0003 16 0 0 0 5.59E+05 3.10E+05 - - - 1.6941 0.994 221125_WJC_METTL3_EV_vs_WT_F08.25081.25081.3 0.0611 4/100 R.EIQLWFQSSELVSWADGGQHSSIHPA.- "sp|O00746|NDKM_HUMAN,tr|Q4TT34|Q4TT34_HUMAN,tr|A0A087WVT9|A0A087WVT9_HUMAN" 3 2908.378 - 124346 25081 3 2908.379718 970.4666 "Nucleoside diphosphate kinase, mitochondrial OS=Homo sapiens OX=9606 GN=NME4 PE=1 SV=1" 4.63 3997 - 47956.7 - - - 0.5835 - 1.052 0.311 - 11.6 1 2 0 0.0017 26 0 0 0 - - - - - 2.1235 0.9998 221125_WJC_METTL3_EV_vs_WT_F08.25091.25091.3 0.00204 May-64 K.ATENDIYNFFSPLNPVR.V "sp|P52597|HNRPF_HUMAN,sp|P31943|HNRH1_HUMAN,tr|H0YBD7|H0YBD7_HUMAN,tr|H0YB39|H0YB39_HUMAN,tr|H0YBG7|H0YBG7_HUMAN,tr|E9PCY7|E9PCY7_HUMAN,tr|G8JLB6|G8JLB6_HUMAN" 7 1995.969 1.81 124354 25091 3 1995.972242 666.3303 Heterogeneous nuclear ribonucleoprotein F OS=Homo sapiens OX=9606 GN=HNRNPF PE=1 SV=3 4.37 3998.4 - 66948.9 - - - 1.6037 - 1.458 0.493 - 29.1 1 2 0 0.0032 17 0 0 0 5.20E+05 2.88E+05 - - - 4.9882 0.9963 221125_WJC_METTL3_EV_vs_WT_F08.25092.25092.4 2.24E-06 15/270 A.ASSPPAGPPPPPAPALVGLPPPPPSPPGFTLPPLGGSLGAGTSTSR.S "sp|O96008|TOM40_HUMAN,tr|K7EJ57|K7EJ57_HUMAN" 2 4215.2368 2.95 124355 25092 4 4215.247422 1054.8165 Mitochondrial import receptor subunit TOM40 homolog OS=Homo sapiens OX=9606 GN=TOMM40 PE=1 SV=1 9.79 3998.5 - 66746.2 - - - 2.5126 - 3.083 0.615 - 38.7 1 1 0 0.0106 46 0 0 0 1.10E+06 3.74E+05 - - - 4.8923 0.9989 221125_WJC_METTL3_EV_vs_WT_F08.25093.25093.3 0.00237 Jun-64 K.ATENDIYNFFSPLNPVR[166.11].V "sp|P52597|HNRPF_HUMAN,sp|P31943|HNRH1_HUMAN,tr|H0YBD7|H0YBD7_HUMAN,tr|H0YB39|H0YB39_HUMAN,tr|H0YBG7|H0YBG7_HUMAN,tr|E9PCY7|E9PCY7_HUMAN,tr|G8JLB6|G8JLB6_HUMAN" 7 2005.9773 1.86 124356 25093 3 2005.981811 669.6664 Heterogeneous nuclear ribonucleoprotein F OS=Homo sapiens OX=9606 GN=HNRNPF PE=1 SV=3 4.37 3998.7 - 59795.8 - - - 2.2433 - 1.443 0.395 - 38.4 1 2 0 0.0045 17 0 0 0 5.34E+05 2.88E+05 - - - 3.8691 0.9974 221125_WJC_METTL3_EV_vs_WT_F08.25102.25102.3 0.00636 Jun-52 K.K[136.11]GPGEVAGTVTGQK[136.11].R "sp|Q86U44|MTA70_HUMAN,tr|F5H6D8|F5H6D8_HUMAN,tr|H0YFV6|H0YFV6_HUMAN,tr|B4DTN4|B4DTN4_HUMAN" 4 1343.738 0.06 124362 25102 3 1343.740919 448.9199 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 8.59 3999.9 - 83556.8 - - - 2.1879 - 1.158 0.382 - 19.6 1 2 0 0.0029 14 0 0 0 5.63E+04 9.88E+05 - - - 3.1879 0.9998 221125_WJC_METTL3_EV_vs_WT_F08.25117.25117.3 0.00156 Aug-88 K.SINPDEAVAYGAAVQAAILSGDK[136.11].S "sp|P11142|HSP7C_HUMAN,tr|E9PNE6|E9PNE6_HUMAN,tr|A8K7Q2|A8K7Q2_HUMAN,tr|E9PKE3|E9PKE3_HUMAN" 4 2267.1525 0.03 124371 25117 3 2267.155996 756.7248 Heat shock cognate 71 kDa protein OS=Homo sapiens OX=9606 GN=HSPA8 PE=1 SV=1 4.03 4001.8 - 42713.3 - - - 1.5456 - 1.369 0.493 - 41 1 2 0 0.0035 23 0 0 0 1.83E+04 6.38E+05 - - - 4.7723 1 221125_WJC_METTL3_EV_vs_WT_F08.25124.25124.4 1.62E-10 8/210 K.TC[160.03]NC[160.03]ETEDYGEKFDENDVITC[160.03]FANFESDEVELSYAK.N "sp|Q00839|HNRPU_HUMAN,tr|A0A1W2PQL0|A0A1W2PQL0_HUMAN,tr|A0A1W2PPL4|A0A1W2PPL4_HUMAN,tr|A0A1W2PQ74|A0A1W2PQ74_HUMAN,tr|Q5RI18|Q5RI18_HUMAN,tr|A0A1W2PP35|A0A1W2PP35_HUMAN,tr|A0A1W2PPS1|A0A1W2PPS1_HUMAN,tr|A0A1W2PRZ7|A0A1W2PRZ7_HUMAN,tr|A0A1W2PPH7|A0A1W2PPH7_HUMAN,tr|A0A1W2PP34|A0A1W2PP34_HUMAN,tr|A0A1X7SBS1|A0A1X7SBS1_HUMAN" 11 4327.7668 0.81 124375 25124 4 4327.767879 1082.949 Heterogeneous nuclear ribonucleoprotein U OS=Homo sapiens OX=9606 GN=HNRNPU PE=1 SV=6 3.73 4002.7 - 78879.9 - - - 0.2535 - 2.155 0.799 - 30.2 1 2 1 0.0011 36 0 0 0 1.28E+06 1.59E+06 - - - 6.4065 1 221125_WJC_METTL3_EV_vs_WT_F08.25142.25142.3 1.74E-10 15/108 R.AEQDSTTVAAFASSLVSGLNSSASEPAK[136.11].E "sp|Q86U44|MTA70_HUMAN,tr|F5H6D8|F5H6D8_HUMAN,tr|H0YFV6|H0YFV6_HUMAN,tr|B4DTN4|B4DTN4_HUMAN" 4 2732.3232 0 124385 25142 3 2733.327323 911.7817 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 4.14 4005.3 - 131649 - - - 367.4986 - 3.332 0.718 - 150 1 2 0 1.0041 28 0 0 0 1.23E+04 3.01E+06 - - - 9.0358 0.9361 221125_WJC_METTL3_EV_vs_WT_F08.25149.25149.3 1.85E-08 15/100 H.NVQPNWITLGNQLDGIHLLDPDVVAR[166.11].F sp|Q86U44|MTA70_HUMAN 1 2906.5278 0.001 124388 25149 3 2907.533402 969.8499 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 4.41 4006.4 - 62570.3 - - - 345.9767 - 2.988 0.549 - 113 1 1 0 1.0056 26 0 0 0 0.00E+00 1.82E+06 - - - 6.9005 0.9854 221125_WJC_METTL3_EV_vs_WT_F08.25152.25152.3 0.00606 May-56 R.QNLEPLFEQYINNLR.R "sp|P48668|K2C6C_HUMAN,sp|P04259|K2C6B_HUMAN,sp|P13647|K2C5_HUMAN,sp|P02538|K2C6A_HUMAN,tr|F8W0C6|F8W0C6_HUMAN" 5 1889.9636 -1 124389 25152 3 1889.970881 630.9951 "Keratin, type II cytoskeletal 6C OS=Homo sapiens OX=9606 GN=KRT6C PE=1 SV=3" 4.53 4006.8 - 38220.7 - - - 3.8726 - 1.202 0.341 - 19.3 1 2 0 0.0073 15 0 0 0 0.00E+00 0.00E+00 - - - 2.8199 1 221125_WJC_METTL3_EV_vs_WT_F08.25890.25890.3 0.00838 21/52 K.K[136.11]GPGEVAGTVTGQK[136.11].R "sp|Q86U44|MTA70_HUMAN,tr|F5H6D8|F5H6D8_HUMAN,tr|H0YFV6|H0YFV6_HUMAN,tr|B4DTN4|B4DTN4_HUMAN" 4 1343.738 0.001 124519 25890 3 1343.74099 448.9199 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 8.59 4136.4 - 1.71E+06 - - - 2.2408 - 3.695 0.561 - 724.5 1 2 0 0.003 14 0 0 0 0.00E+00 3.18E+06 - - - 8.2671 1 221125_WJC_METTL3_EV_vs_WT_F08.25891.25891.2 8.77E-06 18/26 K.K[136.11]GPGEVAGTVTGQK[136.11].R "sp|Q86U44|MTA70_HUMAN,tr|F5H6D8|F5H6D8_HUMAN,tr|H0YFV6|H0YFV6_HUMAN,tr|B4DTN4|B4DTN4_HUMAN" 4 1343.738 -1 124520 25891 2 1343.740774 672.8763 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 8.59 4136.5 - 256499 - - - 2.08 - 3.585 0.548 - 803.1 1 2 0 0.0028 14 0 0 0 0.00E+00 0.00E+00 - - - 6.2916 0.999 221125_WJC_METTL3_EV_vs_WT_F09.02363.02363.2 0.0346 14-Nov K.TSNEHLQK.H sp|P12270|TPR_HUMAN 1 955.4723 640.25 124552 2363 2 955.472013 478.7434 Nucleoprotein TPR OS=Homo sapiens OX=9606 GN=TPR PE=1 SV=3 6.41 1176.3 - 5.37E+06 - - - -0.3098 - 1.493 0.285 - 310.7 1 2 0 -0.0003 8 0 0 0 6.65E+06 1.04E+04 - - - 2.3547 0.9134 221125_WJC_METTL3_EV_vs_WT_F09.02382.02382.2 2.49 12-Aug R.R[166.11]QEIEQK[136.11].L sp|Q9H307|PININ_HUMAN 1 947.5155 4.29 124570 2382 2 947.511495 474.765 Pinin OS=Homo sapiens OX=9606 GN=PNN PE=1 SV=5 6.14 1178.2 - 1.00E+07 - - - -4.2416 - 1.474 0.063 - 356.3 1 2 0 -0.004 7 0 0 0 7.27E+07 1.70E+07 - - - 0.7344 0.9945 221125_WJC_METTL3_EV_vs_WT_F09.02389.02389.2 0.00262 14-Aug R.DYGHSSSR[166.11].D "sp|Q96E39|RMXL1_HUMAN,sp|P38159|RBMX_HUMAN,tr|H3BUY5|H3BUY5_HUMAN,tr|H3BT71|H3BT71_HUMAN,tr|H0Y6E7|H0Y6E7_HUMAN" 5 917.3867 1.7 124577 2389 2 917.382886 459.7006 "RNA binding motif protein, X-linked-like-1 OS=Homo sapiens OX=9606 GN=RBMXL1 PE=1 SV=1" 6.74 1178.7 - 978407 - - - -4.1335 - 1.28 0.428 - 274.6 1 2 0 -0.0038 8 0 0 0 2.61E+07 1.53E+07 - - - 2.9455 0.9797 221125_WJC_METTL3_EV_vs_WT_F09.02394.02394.2 0.0407 16-Sep K.ANSQPSAGR[166.11].A "sp|P15927|RFA2_HUMAN,tr|Q5TEJ0|Q5TEJ0_HUMAN" 2 896.434 1.4 124582 2394 2 896.428872 449.2243 Replication protein A 32 kDa subunit OS=Homo sapiens OX=9606 GN=RPA2 PE=1 SV=1 9.79 1179.3 - 474316 - - - -5.6792 - 1.939 0.242 - 309 1 2 0 -0.0051 9 0 0 0 1.09E+07 7.77E+06 - - - 2.7425 0.9968 221125_WJC_METTL3_EV_vs_WT_F09.02397.02397.2 0.00251 16-Jun K.YNHDGEAGR.L "sp|Q9BUK6|MSTO1_HUMAN,tr|A0A3B3IUD2|A0A3B3IUD2_HUMAN" 2 1017.4264 1.18 124585 2397 2 1017.422504 509.7205 Protein misato homolog 1 OS=Homo sapiens OX=9606 GN=MSTO1 PE=1 SV=1 5.32 1179.7 - 410157 - - - -3.8499 - 1.282 0.481 - 133.5 1 2 0 -0.0039 9 0 0 0 6.33E+05 5.37E+05 - - - 3.3111 0.9326 221125_WJC_METTL3_EV_vs_WT_F09.02400.02400.2 0.0138 14-Aug R.SSGLSQHR.R "sp|Q9NW07|ZN358_HUMAN,sp|Q9UC06|ZNF70_HUMAN" 2 870.4308 -1 124587 2400 2 870.424776 436.2227 Zinc finger protein 358 OS=Homo sapiens OX=9606 GN=ZNF358 PE=1 SV=2 9.49 1180.1 - 973979 - - - -6.8954 - 1.476 0.29 - 156.9 1 2 0 -0.006 8 0 0 0 0.00E+00 0.00E+00 - - - 2.3553 0.9815 221125_WJC_METTL3_EV_vs_WT_F09.02401.02401.2 0.0369 14-Oct K.HLEQQAEK[136.11].M "sp|Q6Y7W6|GGYF2_HUMAN,tr|A0A7I2V3H7|A0A7I2V3H7_HUMAN,tr|I1E4Y6|I1E4Y6_HUMAN,tr|A0A7I2V516|A0A7I2V516_HUMAN,tr|A0A7I2V3H0|A0A7I2V3H0_HUMAN,tr|C9JHW1|C9JHW1_HUMAN,tr|A0A7I2V361|A0A7I2V361_HUMAN,tr|E7ESB6|E7ESB6_HUMAN" 8 989.5022 2.92 124588 2401 2 989.497311 495.7584 GRB10-interacting GYF protein 2 OS=Homo sapiens OX=9606 GN=GIGYF2 PE=1 SV=1 5.4 1180.2 - 337299 - - - -4.8994 - 1.549 0.266 - 321.6 1 2 0 -0.0048 8 0 0 0 2.63E+06 9.01E+05 - - - 2.324 0.9964 221125_WJC_METTL3_EV_vs_WT_F09.02402.02402.2 0.000126 14-Sep R.DYGHSSSR.D "sp|Q96E39|RMXL1_HUMAN,sp|P38159|RBMX_HUMAN,tr|H3BUY5|H3BUY5_HUMAN,tr|H3BT71|H3BT71_HUMAN,tr|H0Y6E7|H0Y6E7_HUMAN" 5 907.3784 1.71 124589 2402 2 907.374447 454.6965 "RNA binding motif protein, X-linked-like-1 OS=Homo sapiens OX=9606 GN=RBMXL1 PE=1 SV=1" 6.74 1180.2 - 5.04E+06 - - - -4.3653 - 1.492 0.453 - 325.9 1 2 0 -0.004 8 0 0 0 2.62E+07 1.53E+07 - - - 3.5924 0.9925 221125_WJC_METTL3_EV_vs_WT_F09.02403.02403.2 0.00373 14-Sep K.K[136.11]INPENSK[136.11].L sp|Q9Y266|NUDC_HUMAN 1 944.5262 1.84 124590 2403 2 944.52212 473.2704 Nuclear migration protein nudC OS=Homo sapiens OX=9606 GN=NUDC PE=1 SV=1 8.59 1180.3 - 4.73E+06 - - - -4.3143 - 1.862 0.252 - 251.6 1 2 0 -0.0041 8 0 0 0 1.04E+08 5.66E+07 - - - 2.7759 0.9979 221125_WJC_METTL3_EV_vs_WT_F09.02405.02405.2 0.00423 16-Aug R.TSSSTTPNR.K "sp|Q9ULV3|CIZ1_HUMAN,tr|Q5SYW2|Q5SYW2_HUMAN,tr|F5H2X7|F5H2X7_HUMAN,tr|H0Y5D5|H0Y5D5_HUMAN,tr|A0A494C0L7|A0A494C0L7_HUMAN,tr|Q9BTG3|Q9BTG3_HUMAN,tr|F6VD24|F6VD24_HUMAN" 7 949.4465 3.48 124592 2405 2 949.443318 475.7305 Cip1-interacting zinc finger protein OS=Homo sapiens OX=9606 GN=CIZ1 PE=1 SV=2 9.41 1180.4 - 3.79E+06 - - - -3.3388 - 1.463 0.438 - 228.4 1 2 0 -0.0032 9 0 0 0 5.52E+06 1.58E+06 - - - 3.3758 0.9986 221125_WJC_METTL3_EV_vs_WT_F09.02406.02406.2 0.000886 16-Oct K.TATAVAHC[160.03]K[136.11].R "sp|P62249|RS16_HUMAN,tr|M0R210|M0R210_HUMAN,tr|M0R3H0|M0R3H0_HUMAN,tr|M0R1M5|M0R1M5_HUMAN,tr|Q6IPX4|Q6IPX4_HUMAN" 5 965.4844 0.65 124593 2406 2 965.48017 483.7495 40S ribosomal protein S16 OS=Homo sapiens OX=9606 GN=RPS16 PE=1 SV=2 7.92 1180.5 - 1.24E+06 - - - -4.3812 - 2.031 0.531 - 407.2 1 2 0 -0.0042 9 0 0 0 5.20E+06 7.95E+06 - - - 5.0114 0.9991 221125_WJC_METTL3_EV_vs_WT_F09.02408.02408.2 9.54E-05 16-Nov R.C[160.03]QQC[160.03]QAEAK.C "sp|P29590|PML_HUMAN,tr|H3BT57|H3BT57_HUMAN" 2 1121.4594 1.01 124595 2408 2 1121.454755 561.737 Protein PML OS=Homo sapiens OX=9606 GN=PML PE=1 SV=3 5.99 1180.7 - 807876 - - - -4.1223 - 2.136 0.59 - 631.9 1 2 0 -0.0046 9 0 0 0 6.46E+06 6.39E+06 - - - 5.5929 1 221125_WJC_METTL3_EV_vs_WT_F09.02409.02409.2 5.21E-07 16-Nov R.C[160.03]QQC[160.03]QAEAK[136.11].C "sp|P29590|PML_HUMAN,tr|H3BT57|H3BT57_HUMAN" 2 1129.4736 1.01 124596 2409 2 1129.468871 565.7441 Protein PML OS=Homo sapiens OX=9606 GN=PML PE=1 SV=3 5.99 1180.8 - 805660 - - - -4.1674 - 2.12 0.671 - 611.9 1 2 0 -0.0047 9 0 0 0 6.46E+06 6.39E+06 - - - 6.1694 0.9936 221125_WJC_METTL3_EV_vs_WT_F09.02410.02410.2 0.00208 20-Oct K.SLSSTSAGGKK.Q "sp|Q6W2J9|BCOR_HUMAN,tr|H7BZ37|H7BZ37_HUMAN,tr|H7C2V9|H7C2V9_HUMAN,tr|H7BYY2|H7BYY2_HUMAN,tr|H7C231|H7C231_HUMAN" 5 1021.5404 -1 124597 2410 2 1021.533985 511.7775 BCL-6 corepressor OS=Homo sapiens OX=9606 GN=BCOR PE=1 SV=1 10 1180.9 - 456397 - - - -6.268 - 2.129 0.479 - 222.4 1 2 0 -0.0064 11 0 0 0 0.00E+00 0.00E+00 - - - 4.6211 0.9852 221125_WJC_METTL3_EV_vs_WT_F09.02417.02417.2 0.139 14-Nov R.KQSEGLTK.E "sp|P51572|BAP31_HUMAN,tr|A0A2R8Y5M6|A0A2R8Y5M6_HUMAN" 2 889.4869 0.59 124602 2417 2 889.483081 445.7507 B-cell receptor-associated protein 31 OS=Homo sapiens OX=9606 GN=BCAP31 PE=1 SV=3 8.59 1181.9 - 2.64E+06 - - - -4.289 - 1.943 0.149 - 375.2 1 2 0 -0.0038 8 0 0 0 1.99E+07 3.35E+07 - - - 2.1436 1 221125_WJC_METTL3_EV_vs_WT_F09.02419.02419.2 9.50E-08 16-Nov R.TEC[160.03]NQC[160.03]GDR[166.11].G tr|H7BY36|H7BY36_HUMAN 1 1148.4214 0.92 124604 2419 2 1148.416385 575.218 RNA-binding protein EWS (Fragment) OS=Homo sapiens OX=9606 GN=EWSR1 PE=1 SV=1 4.37 1182.1 - 1.31E+06 - - - -4.3895 - 2.159 0.756 - 628.1 1 2 0 -0.005 9 0 0 0 1.68E+07 1.82E+07 - - - 6.8499 1 221125_WJC_METTL3_EV_vs_WT_F09.02422.02422.2 2.62E-06 16-Oct R.TEC[160.03]NQC[160.03]GDR.G tr|H7BY36|H7BY36_HUMAN 1 1138.4132 0.92 124607 2422 2 1138.40829 570.2139 RNA-binding protein EWS (Fragment) OS=Homo sapiens OX=9606 GN=EWSR1 PE=1 SV=1 4.37 1182.3 - 755574 - - - -4.2744 - 2.195 0.667 - 486.9 1 2 0 -0.0049 9 0 0 0 1.68E+07 1.82E+07 - - - 6.2404 0.999 221125_WJC_METTL3_EV_vs_WT_F09.02423.02423.2 9.81E-06 18-Nov K.LVQEQGSHSK.F sp|P35580|MYH10_HUMAN 1 1111.5622 0.95 124608 2423 2 1111.558102 556.7884 Myosin-10 OS=Homo sapiens OX=9606 GN=MYH10 PE=1 SV=3 6.75 1182.4 - 536110 - - - -3.6741 - 2.01 0.504 - 396.6 1 2 0 -0.0041 10 0 0 0 2.09E+07 2.21E+07 - - - 4.711 0.8175 221125_WJC_METTL3_EV_vs_WT_F09.02426.02426.2 0.0852 14-Jun T.ATAVAHC[160.03]K[136.11].R "sp|P62249|RS16_HUMAN,tr|M0R210|M0R210_HUMAN,tr|M0R3H0|M0R3H0_HUMAN,tr|M0R1M5|M0R1M5_HUMAN,tr|Q6IPX4|Q6IPX4_HUMAN" 5 864.4367 0.99 124611 2426 2 864.436012 433.2256 40S ribosomal protein S16 OS=Homo sapiens OX=9606 GN=RPS16 PE=1 SV=2 8.27 1182.8 - 428131 - - - -0.8213 - 1.358 0.195 - 127 1 1 0 -0.0007 8 0 0 0 2.11E+06 2.14E+06 - - - 1.404 0.8442 221125_WJC_METTL3_EV_vs_WT_F09.02429.02429.2 0.00301 22-May S.QAAGDNQGDEAK.E "sp|Q9Y2W1|TR150_HUMAN,tr|A0A3B3ITZ9|A0A3B3ITZ9_HUMAN" 2 1202.5164 4.49 124614 2429 2 1202.511633 602.2655 Thyroid hormone receptor-associated protein 3 OS=Homo sapiens OX=9606 GN=THRAP3 PE=1 SV=2 4.03 1183.2 - 249969 - - - -3.9293 - 1.405 0.471 - 104.4 1 1 0 -0.0047 12 0 0 0 1.88E+06 4.20E+05 - - - 3.413 0.9985 221125_WJC_METTL3_EV_vs_WT_F09.02433.02433.2 0.00114 18-Nov K.LVQEQGSHSK[136.11].F sp|P35580|MYH10_HUMAN 1 1119.5764 0.95 124616 2433 2 1119.571897 560.7955 Myosin-10 OS=Homo sapiens OX=9606 GN=MYH10 PE=1 SV=3 6.75 1183.7 - 2.63E+06 - - - -4.0096 - 2.13 0.445 - 388.6 1 2 0 -0.0045 10 0 0 0 2.09E+07 2.21E+07 - - - 4.4369 0.9982 221125_WJC_METTL3_EV_vs_WT_F09.02435.02435.2 4.77E-05 20-Nov K.GNGSSQPGTAR[166.11].R sp|Q9UL25|RAB21_HUMAN 1 1040.4875 0.6 124618 2435 2 1040.482311 521.251 Ras-related protein Rab-21 OS=Homo sapiens OX=9606 GN=RAB21 PE=1 SV=3 9.75 1183.9 - 762372 - - - -4.9438 - 2.304 0.532 - 346.1 1 2 0 -0.0051 11 0 0 0 1.49E+07 2.48E+07 - - - 5.2267 0.8715 221125_WJC_METTL3_EV_vs_WT_F09.02440.02440.2 0.000555 16-Dec A.GAHLQGGAK[136.11].R "sp|P04406|G3P_HUMAN,tr|E7EUT5|E7EUT5_HUMAN" 2 845.4599 1.05 124623 2440 2 845.455577 423.7372 Glyceraldehyde-3-phosphate dehydrogenase OS=Homo sapiens OX=9606 GN=GAPDH PE=1 SV=3 8.76 1184.6 - 319128 - - - -5.1132 - 2.203 0.485 - 553.7 1 1 0 -0.0043 9 0 0 0 2.96E+07 2.81E+07 - - - 4.9068 0.9986 221125_WJC_METTL3_EV_vs_WT_F09.02446.02446.2 0.0128 14/18 K.AGAHLQGGAK[136.11].R "sp|P04406|G3P_HUMAN,tr|E7EUT5|E7EUT5_HUMAN" 2 916.497 1.05 124627 2446 2 916.493118 459.2558 Glyceraldehyde-3-phosphate dehydrogenase OS=Homo sapiens OX=9606 GN=GAPDH PE=1 SV=3 8.8 1185.4 - 1.74E+06 - - - -4.251 - 2.237 0.469 - 661.3 1 2 0 -0.0039 10 0 0 0 2.56E+07 2.44E+07 - - - 4.7512 0.8479 221125_WJC_METTL3_EV_vs_WT_F09.02447.02447.2 0.0138 16-Dec A.GAHLQGGAK.R "sp|P04406|G3P_HUMAN,tr|E7EUT5|E7EUT5_HUMAN" 2 837.4457 1.05 124628 2447 2 837.44194 419.7301 Glyceraldehyde-3-phosphate dehydrogenase OS=Homo sapiens OX=9606 GN=GAPDH PE=1 SV=3 8.76 1185.5 - 1.78E+06 - - - -4.4898 - 2.067 0.378 - 583.3 1 1 0 -0.0038 9 0 0 0 2.96E+07 2.81E+07 - - - 3.9324 0.9989 221125_WJC_METTL3_EV_vs_WT_F09.02448.02448.2 6.91E-07 20-Nov K.GNGSSQPGTAR.R sp|Q9UL25|RAB21_HUMAN 1 1030.4792 0.6 124629 2448 2 1030.474656 516.2469 Ras-related protein Rab-21 OS=Homo sapiens OX=9606 GN=RAB21 PE=1 SV=3 9.75 1185.6 - 1.36E+06 - - - -4.395 - 2.352 0.563 - 349.4 1 2 0 -0.0045 11 0 0 0 1.49E+07 2.48E+07 - - - 5.5116 0.9994 221125_WJC_METTL3_EV_vs_WT_F09.02452.02452.2 0.000473 18-Dec R.SSNTEQNGVK.D sp|Q9H7E2|TDRD3_HUMAN 1 1062.4942 1.84 124633 2452 2 1062.49071 532.2544 Tudor domain-containing protein 3 OS=Homo sapiens OX=9606 GN=TDRD3 PE=1 SV=1 5.72 1186 - 390697 - - - -3.2527 - 2.266 0.496 - 733 1 2 0 -0.0035 10 0 0 0 2.73E+06 1.48E+06 - - - 4.9867 0.9986 221125_WJC_METTL3_EV_vs_WT_F09.02457.02457.2 0.00354 18-Dec K.AGAHLQGGAK.R "sp|P04406|G3P_HUMAN,tr|E7EUT5|E7EUT5_HUMAN" 2 908.4828 1.05 124636 2457 2 908.479231 455.2487 Glyceraldehyde-3-phosphate dehydrogenase OS=Homo sapiens OX=9606 GN=GAPDH PE=1 SV=3 8.8 1186.7 - 3.82E+06 - - - -3.9439 - 2.377 0.402 - 578.7 1 2 0 -0.0036 10 0 0 0 2.56E+07 2.44E+07 - - - 4.4259 0.9667 221125_WJC_METTL3_EV_vs_WT_F09.02460.02460.2 0.145 16-Jul K.ASDADR[166.11]PC[160.03]R[166.11].K "sp|Q86U44|MTA70_HUMAN,tr|H0YFV6|H0YFV6_HUMAN" 2 1066.4729 0 124639 2460 2 1066.468838 534.2437 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 6 1186.9 - 915968 - - - -3.791 - 1.158 0.237 - 100.8 1 2 0 -0.004 9 0 0 0 6.37E+06 2.28E+09 - - - 1.2146 0.9994 221125_WJC_METTL3_EV_vs_WT_F09.02461.02461.2 3.11E-05 20-Sep K.ADSC[160.03]SQAAGTK.G sp|Q9H7N4|SFR19_HUMAN 1 1094.4662 2.25 124640 2461 2 1094.46234 548.2404 "Splicing factor, arginine\serine-rich 19 OS=Homo sapiens OX=9606 GN=SCAF1 PE=1 SV=3" 5.87 1187.1 - 760105 - - - -3.5606 - 2.146 0.58 - 344 1 2 0 -0.0039 11 0 0 0 5.04E+06 2.24E+06 - - - 5.3894 0.95 221125_WJC_METTL3_EV_vs_WT_F09.02462.02462.2 1.05 16-Jul K.ANSQPSAGR.A "sp|P15927|RFA2_HUMAN,tr|Q5TEJ0|Q5TEJ0_HUMAN" 2 886.4257 0.91 124641 2462 2 886.422132 444.2201 Replication protein A 32 kDa subunit OS=Homo sapiens OX=9606 GN=RPA2 PE=1 SV=1 9.79 1187.2 - 742802 - - - -4.0173 - 1.464 0.12 - 170.4 1 2 0 -0.0036 9 0 0 0 1.49E+07 1.64E+07 - - - 1.029 0.7981 221125_WJC_METTL3_EV_vs_WT_F09.02464.02464.2 1.43 12-Jun K.KEPVTTR.Q "sp|Q04695|K1C17_HUMAN,tr|F5GWP8|F5GWP8_HUMAN" 2 829.4658 46.16 124643 2464 2 829.462411 415.7402 "Keratin, type I cytoskeletal 17 OS=Homo sapiens OX=9606 GN=KRT17 PE=1 SV=2" 8.75 1187.4 - 330417 - - - -4.046 - 1.115 0.083 - 182.3 1 2 0 -0.0034 7 0 0 0 2.22E+06 4.81E+04 - - - -0.0021 1 221125_WJC_METTL3_EV_vs_WT_F09.02465.02465.2 3.09E-06 20-Nov K.ADSC[160.03]SQAAGTK[136.11].G sp|Q9H7N4|SFR19_HUMAN 1 1102.4804 2.25 124644 2465 2 1102.475773 552.2475 "Splicing factor, arginine\serine-rich 19 OS=Homo sapiens OX=9606 GN=SCAF1 PE=1 SV=3" 5.87 1187.6 - 304762 - - - -4.2305 - 2.323 0.602 - 598.7 1 2 0 -0.0047 11 0 0 0 5.04E+06 2.24E+06 - - - 5.766 0.9967 221125_WJC_METTL3_EV_vs_WT_F09.02466.02466.2 0.0372 16-Aug K.EDPDGEHAR.R "sp|P52272|HNRPM_HUMAN,tr|M0R019|M0R019_HUMAN,tr|M0R0N3|M0R0N3_HUMAN,tr|A0A087X0X3|A0A087X0X3_HUMAN,tr|M0QYQ7|M0QYQ7_HUMAN,tr|M0R2T0|M0R2T0_HUMAN" 6 1024.421 3.05 124645 2466 2 1024.416089 513.2178 Heterogeneous nuclear ribonucleoprotein M OS=Homo sapiens OX=9606 GN=HNRNPM PE=1 SV=3 4.31 1187.7 - 208331 - - - -4.7949 - 1.651 0.487 - 299.6 1 2 0 -0.0049 9 0 0 0 1.95E+07 6.40E+06 - - - 4.087 1 221125_WJC_METTL3_EV_vs_WT_F09.02472.02472.2 4.95E-05 13/20 K.TAAAAAEHSQR[166.11].E sp|O43242|PSMD3_HUMAN 1 1121.5453 0.45 124649 2472 2 1121.540446 561.7799 26S proteasome non-ATPase regulatory subunit 3 OS=Homo sapiens OX=9606 GN=PSMD3 PE=1 SV=2 6.41 1188.4 - 1.62E+06 - - - -4.3315 - 2.834 0.545 - 847.1 1 2 0 -0.0049 11 0 0 0 1.07E+07 2.39E+07 - - - 5.8829 0.9865 221125_WJC_METTL3_EV_vs_WT_F09.02476.02476.2 0.000104 15/20 K.TAAAAAEHSQR.E sp|O43242|PSMD3_HUMAN 1 1111.537 0.45 124653 2476 2 1111.526495 556.7758 26S proteasome non-ATPase regulatory subunit 3 OS=Homo sapiens OX=9606 GN=PSMD3 PE=1 SV=2 6.41 1188.9 - 743302 - - - -9.4815 - 2.75 0.515 - 1097.3 1 2 0 -0.0105 11 0 0 0 1.07E+07 2.39E+07 - - - 5.5781 0.9962 221125_WJC_METTL3_EV_vs_WT_F09.02477.02477.2 0.000369 16-Aug K.EDPDGEHAR[166.11].R "sp|P52272|HNRPM_HUMAN,tr|M0R019|M0R019_HUMAN,tr|M0R0N3|M0R0N3_HUMAN,tr|A0A087X0X3|A0A087X0X3_HUMAN,tr|M0QYQ7|M0QYQ7_HUMAN,tr|M0R2T0|M0R2T0_HUMAN" 6 1034.4293 3.05 124654 2477 2 1034.423723 518.2219 Heterogeneous nuclear ribonucleoprotein M OS=Homo sapiens OX=9606 GN=HNRNPM PE=1 SV=3 4.31 1189 - 595502 - - - -5.3633 - 1.585 0.556 - 292.2 1 2 0 -0.0055 9 0 0 0 1.95E+07 6.40E+06 - - - 4.4784 0.9915 221125_WJC_METTL3_EV_vs_WT_F09.02483.02483.2 0.0541 16-Jul K.VDPSHDASK.V "sp|O75369|FLNB_HUMAN,sp|Q14315|FLNC_HUMAN,tr|E7EN95|E7EN95_HUMAN,tr|A0A804HK76|A0A804HK76_HUMAN,tr|A0A804HL72|A0A804HL72_HUMAN" 5 954.4407 0.84 124660 2483 2 954.437248 478.2276 Filamin-B OS=Homo sapiens OX=9606 GN=FLNB PE=1 SV=2 5.21 1189.8 - 270956 - - - -3.5895 - 1.297 0.324 - 177.6 1 2 0 -0.0034 9 0 0 0 2.91E+06 3.45E+06 - - - 2.1853 0.8941 221125_WJC_METTL3_EV_vs_WT_F09.02484.02484.2 1.45E-05 16-Nov A.AAAAEHSQR.E sp|O43242|PSMD3_HUMAN 1 939.4522 0.43 124661 2484 2 939.44742 470.7334 26S proteasome non-ATPase regulatory subunit 3 OS=Homo sapiens OX=9606 GN=PSMD3 PE=1 SV=2 6.79 1189.9 - 236773 - - - -5.1328 - 2.234 0.544 - 625.9 1 1 0 -0.0048 9 0 0 0 3.99E+06 9.34E+06 - - - 5.3829 0.9866 221125_WJC_METTL3_EV_vs_WT_F09.02491.02491.2 0.000784 14-Jul R.QYNEEGRK.A "sp|Q9BUJ2|HNRL1_HUMAN,tr|A0A0A0MRA5|A0A0A0MRA5_HUMAN,tr|M0R3F1|M0R3F1_HUMAN,tr|B7Z4B8|B7Z4B8_HUMAN" 4 1022.4781 1.75 124666 2491 2 1022.472778 512.2463 Heterogeneous nuclear ribonucleoprotein U-like protein 1 OS=Homo sapiens OX=9606 GN=HNRNPUL1 PE=1 SV=2 6.14 1190.7 - 3.20E+06 - - - -5.2265 - 1.367 0.387 - 209.9 1 2 0 -0.0053 8 0 0 0 2.88E+07 1.65E+07 - - - 2.8405 0.9992 221125_WJC_METTL3_EV_vs_WT_F09.02493.02493.2 0.00131 13/16 K.HLNDETTSK[136.11].Q sp|Q9NUQ9|CYRIB_HUMAN 1 1051.5026 0.96 124668 2493 2 1051.498541 526.7586 CYFIP-related Rac1 interactor B OS=Homo sapiens OX=9606 GN=CYRIB PE=1 SV=1 5.32 1190.8 - 1.37E+06 - - - -3.8155 - 2.472 0.48 - 569.3 1 2 0 -0.004 9 0 0 0 2.83E+07 2.94E+07 - - - 5.2033 0.9689 221125_WJC_METTL3_EV_vs_WT_F09.02496.02496.2 0.000267 14-Aug R.HAQTISGH.A "sp|Q9UBN7|HDAC6_HUMAN,tr|A0A2R8Y4G2|A0A2R8Y4G2_HUMAN,tr|A0A2R8YDE6|A0A2R8YDE6_HUMAN" 3 849.4093 - 124671 2496 2 849.410137 425.7119 Histone deacetylase 6 OS=Homo sapiens OX=9606 GN=HDAC6 PE=1 SV=2 6.92 1191.2 - 622870 - - - 0.9689 - 1.398 0.43 - 177.3 1 1 0 0.0008 8 0 0 0 - - - - - 3.2272 0.9984 221125_WJC_METTL3_EV_vs_WT_F09.02503.02503.2 0.00117 16-Nov K.HLNDETTSK.Q sp|Q9NUQ9|CYRIB_HUMAN 1 1043.4884 0.96 124675 2503 2 1043.483235 522.7515 CYFIP-related Rac1 interactor B OS=Homo sapiens OX=9606 GN=CYRIB PE=1 SV=1 5.32 1192 - 1.92E+06 - - - -4.9047 - 2.172 0.56 - 373.3 1 2 0 -0.0051 9 0 0 0 2.83E+07 2.94E+07 - - - 5.4195 0.893 221125_WJC_METTL3_EV_vs_WT_F09.02505.02505.2 1.7 12-May R.KSNVSYK.N sp|Q9Y5B9|SP16H_HUMAN 1 824.4392 1.02 124677 2505 2 824.436247 413.2269 FACT complex subunit SPT16 OS=Homo sapiens OX=9606 GN=SUPT16H PE=1 SV=1 9.7 1192.2 - 296002 - - - -3.6037 - 1.076 0.135 - 93.9 1 2 0 -0.003 7 0 0 0 1.42E+07 1.39E+07 - - - 0.2693 0.944 221125_WJC_METTL3_EV_vs_WT_F09.02510.02510.2 0.199 12-Jul R.K[136.11]SNVSYK[136.11].N sp|Q9Y5B9|SP16H_HUMAN 1 840.4676 1.02 124679 2510 2 840.463517 421.2411 FACT complex subunit SPT16 OS=Homo sapiens OX=9606 GN=SUPT16H PE=1 SV=1 9.7 1192.9 - 598831 - - - -4.8794 - 1.372 0.183 - 156.8 1 2 0 -0.0041 7 0 0 0 1.42E+07 1.39E+07 - - - 1.3935 0.9958 221125_WJC_METTL3_EV_vs_WT_F09.02525.02525.2 2.30E-05 15/20 K.K[136.11]TAEAGGVTGK[136.11].G "sp|P09874|PARP1_HUMAN,tr|A0A7I2V5E9|A0A7I2V5E9_HUMAN,tr|A0A7I2V625|A0A7I2V625_HUMAN,tr|A0A7I2V3E1|A0A7I2V3E1_HUMAN" 4 1033.5739 1.05 124685 2525 2 1033.567482 517.7942 Poly [ADP-ribose] polymerase 1 OS=Homo sapiens OX=9606 GN=PARP1 PE=1 SV=4 8.59 1194.8 - 1.34E+06 - - - -6.1844 - 2.664 0.49 - 640.6 1 2 0 -0.0064 11 0 0 0 6.70E+07 6.37E+07 - - - 5.3088 0.9905 221125_WJC_METTL3_EV_vs_WT_F09.02526.02526.2 1.11E-07 16/20 K.KTAEAGGVTGK.G "sp|P09874|PARP1_HUMAN,tr|A0A7I2V5E9|A0A7I2V5E9_HUMAN,tr|A0A7I2V625|A0A7I2V625_HUMAN,tr|A0A7I2V3E1|A0A7I2V3E1_HUMAN" 4 1017.5455 1.05 124686 2526 2 1017.537634 509.78 Poly [ADP-ribose] polymerase 1 OS=Homo sapiens OX=9606 GN=PARP1 PE=1 SV=4 8.59 1194.9 - 762158 - - - -7.7048 - 2.963 0.493 - 787.2 1 2 0 -0.0078 11 0 0 0 6.70E+07 6.37E+07 - - - 5.6183 0.9597 221125_WJC_METTL3_EV_vs_WT_F09.02534.02534.2 0.567 14-Jun R.ENTHQTLK.C "sp|Q9NX63|MIC19_HUMAN,tr|C9JRZ6|C9JRZ6_HUMAN" 2 969.488 1.39 124690 2534 2 969.48373 485.7513 MICOS complex subunit MIC19 OS=Homo sapiens OX=9606 GN=CHCHD3 PE=1 SV=1 6.85 1195.9 - 601358 - - - -4.3621 - 1.205 0.24 - 118.9 1 2 0 -0.0042 8 0 0 0 8.47E+06 6.07E+06 - - - 1.3747 0.9981 221125_WJC_METTL3_EV_vs_WT_F09.02535.02535.2 0.000182 16-Dec K.K[136.11]IEQDTDTK[136.11].L sp|O00425|IF2B3_HUMAN 1 1092.5634 1.28 124691 2535 2 1092.557793 547.289 Insulin-like growth factor 2 mRNA-binding protein 3 OS=Homo sapiens OX=9606 GN=IGF2BP3 PE=1 SV=2 4.56 1196 - 1.13E+06 - - - -5.1036 - 2.567 0.499 - 479 1 2 0 -0.0056 9 0 0 0 2.68E+07 2.09E+07 - - - 5.4523 0.9944 221125_WJC_METTL3_EV_vs_WT_F09.02542.02542.2 0.00137 16-Aug K.TDSSPNQAR.A "sp|P26599|PTBP1_HUMAN,tr|A0A6Q8PEX4|A0A6Q8PEX4_HUMAN,tr|A6NLN1|A6NLN1_HUMAN,tr|A0A087WU68|A0A087WU68_HUMAN,tr|K7ES59|K7ES59_HUMAN,tr|A0A7I2V4H6|A0A7I2V4H6_HUMAN,tr|A0A7I2V621|A0A7I2V621_HUMAN" 7 974.4417 1.17 124696 2542 2 974.43759 488.2281 Polypyrimidine tract-binding protein 1 OS=Homo sapiens OX=9606 GN=PTBP1 PE=1 SV=1 5.5 1196.8 - 5.81E+06 - - - -4.2558 - 1.742 0.322 - 298.5 1 2 0 -0.0041 9 0 0 0 1.32E+08 1.13E+08 - - - 3.0237 0.9994 221125_WJC_METTL3_EV_vs_WT_F09.02544.02544.2 5.34E-06 18-Sep K.LSSANGHEER.S "sp|Q14498|RBM39_HUMAN,tr|Q5QP22|Q5QP22_HUMAN,tr|F2Z2Z5|F2Z2Z5_HUMAN,tr|H0Y6I9|H0Y6I9_HUMAN,tr|A8MYG5|A8MYG5_HUMAN,tr|Q5QP23|Q5QP23_HUMAN,tr|F8WF24|F8WF24_HUMAN,tr|G3XAC6|G3XAC6_HUMAN" 8 1098.5054 1.27 124698 2544 2 1098.50185 550.26 RNA-binding protein 39 OS=Homo sapiens OX=9606 GN=RBM39 PE=1 SV=2 5.4 1197 - 548819 - - - -3.2317 - 2.041 0.548 - 321 1 2 0 -0.0036 10 0 0 0 7.30E+06 5.73E+06 - - - 5.0788 0.9946 221125_WJC_METTL3_EV_vs_WT_F09.02548.02548.2 0.049 16-Nov K.TDSSPNQAR[166.11].A "sp|P26599|PTBP1_HUMAN,tr|A0A6Q8PEX4|A0A6Q8PEX4_HUMAN,tr|A6NLN1|A6NLN1_HUMAN,tr|A0A087WU68|A0A087WU68_HUMAN,tr|K7ES59|K7ES59_HUMAN,tr|A0A7I2V4H6|A0A7I2V4H6_HUMAN,tr|A0A7I2V621|A0A7I2V621_HUMAN" 7 984.45 1.17 124700 2548 2 984.44638 493.2323 Polypyrimidine tract-binding protein 1 OS=Homo sapiens OX=9606 GN=PTBP1 PE=1 SV=1 5.5 1197.6 - 7.13E+06 - - - -3.6843 - 1.852 0.247 - 608.3 1 2 0 -0.0036 9 0 0 0 1.32E+08 1.13E+08 - - - 2.6471 0.9956 221125_WJC_METTL3_EV_vs_WT_F09.02549.02549.2 0.0387 14-Sep R.DLVHSNKK.E "sp|Q9Y2W1|TR150_HUMAN,tr|A0A3B3ITZ9|A0A3B3ITZ9_HUMAN" 2 939.5138 2.65 124701 2549 2 939.509821 470.7642 Thyroid hormone receptor-associated protein 3 OS=Homo sapiens OX=9606 GN=THRAP3 PE=1 SV=2 8.6 1197.6 - 4.61E+06 - - - -4.2139 - 1.778 0.333 - 361.3 1 2 0 -0.004 8 0 0 0 1.59E+09 6.01E+08 - - - 3.2349 1 221125_WJC_METTL3_EV_vs_WT_F09.02550.02550.2 0.00125 13/16 K.KIEQDTDTK.L sp|O00425|IF2B3_HUMAN 1 1076.535 1.29 124702 2550 2 1076.531101 539.2748 Insulin-like growth factor 2 mRNA-binding protein 3 OS=Homo sapiens OX=9606 GN=IGF2BP3 PE=1 SV=2 4.56 1197.7 - 3.04E+06 - - - -3.593 - 2.707 0.553 - 643.7 1 2 0 -0.0039 9 0 0 0 2.68E+07 2.08E+07 - - - 6.0053 0.9964 221125_WJC_METTL3_EV_vs_WT_F09.02551.02551.2 0.023 14-Oct R.DLVHSNK[136.11]K[136.11].E "sp|Q9Y2W1|TR150_HUMAN,tr|A0A3B3ITZ9|A0A3B3ITZ9_HUMAN" 2 955.5422 2.65 124703 2551 2 955.538295 478.7784 Thyroid hormone receptor-associated protein 3 OS=Homo sapiens OX=9606 GN=THRAP3 PE=1 SV=2 8.6 1197.7 - 2.56E+06 - - - -4.0658 - 1.676 0.373 - 382.6 1 2 0 -0.0039 8 0 0 0 1.59E+09 6.01E+08 - - - 3.3522 0.9996 221125_WJC_METTL3_EV_vs_WT_F09.02554.02554.2 5.96E-05 18-Oct K.LSSANGHEER[166.11].S "sp|Q14498|RBM39_HUMAN,tr|Q5QP22|Q5QP22_HUMAN,tr|F2Z2Z5|F2Z2Z5_HUMAN,tr|H0Y6I9|H0Y6I9_HUMAN,tr|A8MYG5|A8MYG5_HUMAN,tr|Q5QP23|Q5QP23_HUMAN,tr|F8WF24|F8WF24_HUMAN,tr|G3XAC6|G3XAC6_HUMAN" 8 1108.5137 1.28 124706 2554 2 1108.51076 555.2641 RNA-binding protein 39 OS=Homo sapiens OX=9606 GN=RBM39 PE=1 SV=2 5.4 1198.1 - 663257 - - - -2.6251 - 2.198 0.491 - 443.5 1 2 0 -0.0029 10 0 0 0 7.65E+06 5.96E+06 - - - 4.8649 0.8018 221125_WJC_METTL3_EV_vs_WT_F09.02567.02567.2 0.577 12-Jun R.KFGQGSR.S "sp|P62273|RS29_HUMAN,tr|A0A2R8Y6P7|A0A2R8Y6P7_HUMAN,tr|A0A2R8Y851|A0A2R8Y851_HUMAN" 3 778.4086 1.1 124715 2567 2 778.404412 390.2116 40S ribosomal protein S29 OS=Homo sapiens OX=9606 GN=RPS29 PE=1 SV=2 11 1199.7 - 1.42E+06 - - - -5.3622 - 1.199 0.156 - 147.4 2 2 0 -0.0042 7 0 0 0 1.31E+08 1.19E+08 - - - 0.6325 0.9028 221125_WJC_METTL3_EV_vs_WT_F09.02568.02568.2 0.0209 12-Jul R.DLVHSNK.K "sp|Q9Y2W1|TR150_HUMAN,tr|A0A3B3ITZ9|A0A3B3ITZ9_HUMAN" 2 811.4188 1.89 124716 2568 2 811.414533 406.7167 Thyroid hormone receptor-associated protein 3 OS=Homo sapiens OX=9606 GN=THRAP3 PE=1 SV=2 6.74 1199.9 - 1.12E+06 - - - -5.2796 - 1.317 0.17 - 189.8 1 2 0 -0.0043 7 0 0 0 2.96E+07 1.57E+07 - - - 1.1678 0.9828 221125_WJC_METTL3_EV_vs_WT_F09.02571.02571.2 0.00129 16-Sep R.IR[166.11]DPNQGGK[136.11].D "sp|O43432|IF4G3_HUMAN,sp|Q04637|IF4G1_HUMAN,tr|C9J2Z7|C9J2Z7_HUMAN,tr|A0A804HJV5|A0A804HJV5_HUMAN,tr|E7EUU4|E7EUU4_HUMAN,tr|E9PGM1|E9PGM1_HUMAN,tr|A0A0U1RQK7|A0A0U1RQK7_HUMAN,tr|C9J6B6|C9J6B6_HUMAN,tr|A0A0A0MSA7|A0A0A0MSA7_HUMAN,tr|E7EX73|E7EX73_HUMAN,tr|C9K073|C9K073_HUMAN,tr|F8WCF2|F8WCF2_HUMAN,tr|C9JHW9|C9JHW9_HUMAN,tr|B1AN92|B1AN92_HUMAN,tr|A0A7I2Y1C3|A0A7I2Y1C3_HUMAN,tr|C9JF13|C9JF13_HUMAN,tr|B1AN91|B1AN91_HUMAN" 17 1001.5373 0.65 124719 2571 2 1001.533787 501.7759 Eukaryotic translation initiation factor 4 gamma 3 OS=Homo sapiens OX=9606 GN=EIF4G3 PE=1 SV=2 8.75 1200.1 - 819445 - - - -3.5196 - 2.182 0.346 - 332.6 1 2 1 -0.0035 9 0 0 0 1.68E+07 2.60E+07 - - - 3.8527 0.8464 221125_WJC_METTL3_EV_vs_WT_F09.02573.02573.2 0.31 12-Jun R.DLVHSNK[136.11].K "sp|Q9Y2W1|TR150_HUMAN,tr|A0A3B3ITZ9|A0A3B3ITZ9_HUMAN" 2 819.433 1.97 124721 2573 2 819.429053 410.7238 Thyroid hormone receptor-associated protein 3 OS=Homo sapiens OX=9606 GN=THRAP3 PE=1 SV=2 6.74 1200.4 - 741090 - - - -4.8375 - 1.176 0.14 - 118 1 2 0 -0.004 7 0 0 0 2.96E+07 1.50E+07 - - - 0.5875 0.9981 221125_WJC_METTL3_EV_vs_WT_F09.02574.02574.2 0.000134 16-Oct R.NEDEDSPNK.L "sp|P62899|RL31_HUMAN,tr|B7Z4C8|B7Z4C8_HUMAN,tr|B7Z4E3|B7Z4E3_HUMAN,tr|H7C2W9|H7C2W9_HUMAN,tr|C9JU56|C9JU56_HUMAN" 5 1046.4152 2.91 124722 2574 2 1046.410952 524.2149 60S ribosomal protein L31 OS=Homo sapiens OX=9606 GN=RPL31 PE=1 SV=1 3.92 1200.5 - 725493 - - - -4.1045 - 1.803 0.458 - 505.6 1 2 0 -0.0043 9 0 0 0 4.21E+07 1.45E+07 - - - 4.1278 0.9762 221125_WJC_METTL3_EV_vs_WT_F09.02580.02580.2 2.1 12-Jun R.K[136.11]FGQGSR[166.11].S "sp|P62273|RS29_HUMAN,tr|A0A2R8Y6P7|A0A2R8Y6P7_HUMAN,tr|A0A2R8Y851|A0A2R8Y851_HUMAN" 3 796.4311 1.1 124726 2580 2 796.427662 399.2228 40S ribosomal protein S29 OS=Homo sapiens OX=9606 GN=RPS29 PE=1 SV=2 11 1201.2 - 5.69E+06 - - - -4.2615 - 1.394 0.222 - 137.5 1 2 0 -0.0034 7 0 0 0 1.32E+08 1.19E+08 - - - 1.7321 0.9745 221125_WJC_METTL3_EV_vs_WT_F09.02584.02584.2 0.166 12-Jun R.KQDVVNR.V "sp|Q8IWC1|MA7D3_HUMAN,tr|A0A0A0MRP0|A0A0A0MRP0_HUMAN" 2 857.4719 1.12 124730 2584 2 857.468554 429.7432 MAP7 domain-containing protein 3 OS=Homo sapiens OX=9606 GN=MAP7D3 PE=1 SV=2 8.75 1201.6 - 1.15E+06 - - - -3.9197 - 1.287 0.223 - 109.9 1 2 0 -0.0034 7 0 0 0 1.21E+07 1.08E+07 - - - 1.4865 0.9869 221125_WJC_METTL3_EV_vs_WT_F09.02585.02585.2 0.367 18-Sep K.KLADSDQASK.V "sp|Q14980|NUMA1_HUMAN,tr|A0A087WY61|A0A087WY61_HUMAN,tr|H0YFY6|H0YFY6_HUMAN,tr|K4DIE0|K4DIE0_HUMAN" 4 1061.5353 4.42 124731 2585 2 1061.531044 531.7749 Nuclear mitotic apparatus protein 1 OS=Homo sapiens OX=9606 GN=NUMA1 PE=1 SV=2 5.96 1201.7 - 594349 - - - -4.0121 - 1.706 0.209 - 252.4 1 2 0 -0.0043 10 0 0 0 6.56E+06 1.49E+06 - - - 2.0743 0.9809 221125_WJC_METTL3_EV_vs_WT_F09.02586.02586.2 0.0124 18-Jul K.K[136.11]LADSDQASK[136.11].V "sp|Q14980|NUMA1_HUMAN,tr|A0A087WY61|A0A087WY61_HUMAN,tr|H0YFY6|H0YFY6_HUMAN,tr|K4DIE0|K4DIE0_HUMAN" 4 1077.5637 -1 124732 2586 2 1077.557402 539.7891 Nuclear mitotic apparatus protein 1 OS=Homo sapiens OX=9606 GN=NUMA1 PE=1 SV=2 5.96 1201.8 - 412554 - - - -5.8475 - 1.531 0.364 - 143.6 1 2 0 -0.0063 10 0 0 0 0.00E+00 0.00E+00 - - - 2.9164 0.9957 221125_WJC_METTL3_EV_vs_WT_F09.02595.02595.3 0.000147 Oct-36 K.MVEK[136.11]DQDGGR[166.11].K "sp|P39019|RS19_HUMAN,tr|A0A075B6E2|A0A075B6E2_HUMAN" 2 1151.536 0.001 124737 2595 3 1151.530734 384.8526 40S ribosomal protein S19 OS=Homo sapiens OX=9606 GN=RPS19 PE=1 SV=2 4.56 1203 - 1.57E+06 - - - -4.5661 - 1.84 0.458 - 174 1 2 1 -0.0053 10 0 0 0 0.00E+00 9.84E+07 - - - 5.4256 0.9937 221125_WJC_METTL3_EV_vs_WT_F09.02603.02603.2 2.78E-05 18-Oct K.MVEK[136.11]DQDGGR[166.11].K "sp|P39019|RS19_HUMAN,tr|A0A075B6E2|A0A075B6E2_HUMAN" 2 1151.536 1.36 124742 2603 2 1151.532765 576.7753 40S ribosomal protein S19 OS=Homo sapiens OX=9606 GN=RPS19 PE=1 SV=2 4.56 1203.9 - 723151 - - - -2.8023 - 1.789 0.523 - 359.9 1 2 1 -0.0032 10 0 0 0 1.92E+07 1.41E+07 - - - 4.5264 0.9707 221125_WJC_METTL3_EV_vs_WT_F09.02608.02608.2 0.0247 14-Aug K.NR[166.11]PGPQTR[166.11].S "sp|O14744|ANM5_HUMAN,tr|C9JSX3|C9JSX3_HUMAN,tr|G3V580|G3V580_HUMAN,tr|G3V2L6|G3V2L6_HUMAN,tr|G3V5L5|G3V5L5_HUMAN" 5 944.5055 2.58 124745 2608 2 944.500667 473.26 Protein arginine N-methyltransferase 5 OS=Homo sapiens OX=9606 GN=PRMT5 PE=1 SV=4 12 1204.5 - 1.37E+06 - - - -5.1191 - 1.402 0.271 - 139.5 1 2 0 -0.0048 8 0 0 0 4.56E+08 1.77E+08 - - - 2.0602 0.9852 221125_WJC_METTL3_EV_vs_WT_F09.02609.02609.2 0.000168 18-Oct K.MVEKDQDGGR.K "sp|P39019|RS19_HUMAN,tr|A0A075B6E2|A0A075B6E2_HUMAN" 2 1133.5135 1.39 124746 2609 2 1133.509123 567.764 40S ribosomal protein S19 OS=Homo sapiens OX=9606 GN=RPS19 PE=1 SV=2 4.56 1204.6 - 778828 - - - -3.8809 - 1.794 0.509 - 343 1 2 1 -0.0044 10 0 0 0 1.96E+07 1.41E+07 - - - 4.4305 0.9949 221125_WJC_METTL3_EV_vs_WT_F09.02610.02610.2 0.0475 14-Jul K.QVEEKPQR.A sp|Q14008|CKAP5_HUMAN 1 1012.5302 0.86 124747 2610 2 1012.527683 507.2724 Cytoskeleton-associated protein 5 OS=Homo sapiens OX=9606 GN=CKAP5 PE=1 SV=3 6.14 1204.7 - 399649 - - - -2.4444 - 1.254 0.296 - 269.6 1 2 0 -0.0025 8 0 0 0 7.82E+06 9.04E+06 - - - 1.9091 0.9983 221125_WJC_METTL3_EV_vs_WT_F09.02614.02614.2 0.0469 14-Aug K.K[136.11]FQGENTK[136.11].S "sp|Q96CT7|CC124_HUMAN,tr|M0R2F5|M0R2F5_HUMAN" 2 966.5105 1.08 124749 2614 2 966.507581 484.2625 Coiled-coil domain-containing protein 124 OS=Homo sapiens OX=9606 GN=CCDC124 PE=1 SV=1 8.59 1205.2 - 828926 - - - -3.0667 - 1.7 0.371 - 227.7 1 2 0 -0.003 8 0 0 0 2.12E+07 1.96E+07 - - - 3.3806 0.9981 221125_WJC_METTL3_EV_vs_WT_F09.02631.02631.2 0.0134 14-Oct K.KFQGENTK.S "sp|Q96CT7|CC124_HUMAN,tr|M0R2F5|M0R2F5_HUMAN" 2 950.4821 1.07 124762 2631 2 950.479848 476.2483 Coiled-coil domain-containing protein 124 OS=Homo sapiens OX=9606 GN=CCDC124 PE=1 SV=1 8.59 1207.1 - 1.37E+06 - - - -2.4167 - 1.801 0.261 - 332 1 2 0 -0.0023 8 0 0 0 2.12E+07 1.98E+07 - - - 2.7424 0.9978 221125_WJC_METTL3_EV_vs_WT_F09.02632.02632.2 0.00819 12-Jul R.R[166.11]DSASYR[166.11].D "sp|Q92841|DDX17_HUMAN,tr|A0A5H1ZRQ2|A0A5H1ZRQ2_HUMAN,tr|A0A1X7SBZ2|A0A1X7SBZ2_HUMAN" 3 873.4208 1.34 124763 2632 2 873.418891 437.7177 Probable ATP-dependent RNA helicase DDX17 OS=Homo sapiens OX=9606 GN=DDX17 PE=1 SV=2 8.75 1207.2 - 894073 - - - -2.1502 - 1.361 0.331 - 152.9 1 2 0 -0.0019 7 0 0 0 1.19E+07 8.91E+06 - - - 2.4618 0.9985 221125_WJC_METTL3_EV_vs_WT_F09.02638.02638.2 0.0034 14-Sep K.VSDEAVKK.D "sp|O75688|PPM1B_HUMAN,tr|B8ZZF0|B8ZZF0_HUMAN,tr|A0A3B3IS24|A0A3B3IS24_HUMAN,tr|C9JIR6|C9JIR6_HUMAN" 4 874.476 2.7 124766 2638 2 874.473622 438.2453 Protein phosphatase 1B OS=Homo sapiens OX=9606 GN=PPM1B PE=1 SV=1 6.04 1208 - 1.03E+06 - - - -2.7159 - 1.623 0.367 - 206 1 2 0 -0.0024 8 0 0 0 9.01E+06 3.34E+06 - - - 3.2115 0.999 221125_WJC_METTL3_EV_vs_WT_F09.02645.02645.2 0.0142 20-Aug K.TETQTTGAENK[136.11].A "sp|Q9BWU0|NADAP_HUMAN,tr|A0A087X0M4|A0A087X0M4_HUMAN" 2 1186.5557 0.67 124773 2645 2 1186.554711 594.2851 Kanadaptin OS=Homo sapiens OX=9606 GN=SLC4A1AP PE=1 SV=1 4.53 1208.8 - 241340 - - - -0.8428 - 1.399 0.347 - 198.6 1 2 0 -0.001 11 0 0 0 1.18E+06 1.76E+06 - - - 2.5119 0.9776 221125_WJC_METTL3_EV_vs_WT_F09.02646.02646.2 6.47E-05 20-Sep K.TETQTTGAENK.A "sp|Q9BWU0|NADAP_HUMAN,tr|A0A087X0M4|A0A087X0M4_HUMAN" 2 1178.5415 0.67 124774 2646 2 1178.532688 590.278 Kanadaptin OS=Homo sapiens OX=9606 GN=SLC4A1AP PE=1 SV=1 4.53 1209 - 180121 - - - -7.4864 - 1.63 0.482 - 182.4 1 2 0 -0.0088 11 0 0 0 1.18E+06 1.76E+06 - - - 3.92 0.9827 221125_WJC_METTL3_EV_vs_WT_F09.02654.02654.2 0.314 14-Jul K.QQSNEHLR[166.11].R "sp|O43707|ACTN4_HUMAN,tr|F5GXS2|F5GXS2_HUMAN,tr|H7C144|H7C144_HUMAN" 3 1020.4976 0.68 124780 2654 2 1020.492858 511.2561 Alpha-actinin-4 OS=Homo sapiens OX=9606 GN=ACTN4 PE=1 SV=2 6.75 1209.9 - 591789 - - - -4.6722 - 1.581 0.247 - 181.3 1 2 0 -0.0048 8 0 0 0 8.63E+06 1.28E+07 - - - 2.2453 0.9961 221125_WJC_METTL3_EV_vs_WT_F09.02655.02655.2 0.00976 14-Sep K.QQSNEHLR.R "sp|O43707|ACTN4_HUMAN,tr|F5GXS2|F5GXS2_HUMAN,tr|H7C144|H7C144_HUMAN" 3 1010.4894 0.64 124781 2655 2 1010.484464 506.252 Alpha-actinin-4 OS=Homo sapiens OX=9606 GN=ACTN4 PE=1 SV=2 6.75 1210.1 - 549143 - - - -4.8412 - 2.002 0.377 - 479.7 1 2 0 -0.0049 8 0 0 0 8.22E+06 1.28E+07 - - - 3.9175 0.9878 221125_WJC_METTL3_EV_vs_WT_F09.02656.02656.2 0.00439 22-Oct Y.SVSGSGSTAGSR[166.11].T "sp|Q15149|PLEC_HUMAN,tr|H0YDN1|H0YDN1_HUMAN" 2 1061.4977 1.54 124782 2656 2 1061.497913 531.7561 Plectin OS=Homo sapiens OX=9606 GN=PLEC PE=1 SV=3 9.47 1210.2 - 527250 - - - 0.2148 - 2.326 0.381 - 220.4 1 1 0 0.0002 12 0 0 0 4.47E+06 2.91E+06 - - - 4.0761 0.995 221125_WJC_METTL3_EV_vs_WT_F09.02657.02657.2 0.028 14-Aug K.AAHSYNPK[136.11].E sp|Q9BYJ9|YTHD1_HUMAN 1 894.4439 1.93 124783 2657 2 894.441248 448.2292 YTH domain-containing family protein 1 OS=Homo sapiens OX=9606 GN=YTHDF1 PE=1 SV=1 8.64 1210.3 - 465201 - - - -2.9829 - 1.424 0.292 - 186.9 1 2 0 -0.0027 8 0 0 0 9.39E+06 4.86E+06 - - - 2.2629 0.9869 221125_WJC_METTL3_EV_vs_WT_F09.02661.02661.2 0.043 16-Oct K.EEGINK[136.11]SEK[136.11].R "sp|P09874|PARP1_HUMAN,tr|A0A7I2V3E1|A0A7I2V3E1_HUMAN" 2 1048.5372 1.57 124785 2661 2 1048.534352 525.2759 Poly [ADP-ribose] polymerase 1 OS=Homo sapiens OX=9606 GN=PARP1 PE=1 SV=4 4.79 1210.9 - 871891 - - - -2.6723 - 2.141 0.298 - 460.2 1 2 1 -0.0028 9 0 0 0 1.08E+07 6.88E+06 - - - 3.4436 0.7891 221125_WJC_METTL3_EV_vs_WT_F09.02662.02662.2 10.2 12-Aug K.DISENKR.A "sp|P11142|HSP7C_HUMAN,sp|Q13029|PRDM2_HUMAN,tr|E9PNE6|E9PNE6_HUMAN,tr|A8K7Q2|A8K7Q2_HUMAN,tr|E9PKE3|E9PKE3_HUMAN,tr|E9PN89|E9PN89_HUMAN" 6 860.4352 0.16 124786 2662 2 860.431421 431.2249 Heat shock cognate 71 kDa protein OS=Homo sapiens OX=9606 GN=HSPA8 PE=1 SV=1 6.07 1211 - 1.84E+06 - - - -4.3862 - 1.232 0.057 - 194.4 1 2 0 -0.0038 7 0 0 0 5.41E+07 3.48E+08 - - - 0.1219 0.992 221125_WJC_METTL3_EV_vs_WT_F09.02666.02666.2 0.0361 16-Jul R.R[166.11]AVSPSNPK[136.11].A "sp|Q14244|MAP7_HUMAN,tr|A0A087WZ40|A0A087WZ40_HUMAN" 2 972.5471 28.3 124790 2666 2 972.543931 487.2809 Ensconsin OS=Homo sapiens OX=9606 GN=MAP7 PE=1 SV=1 11 1211.5 - 431581 - - - -3.3088 - 1.389 0.28 - 185.5 1 2 0 -0.0032 9 0 0 0 2.18E+08 7.69E+06 - - - 2.0587 0.9973 221125_WJC_METTL3_EV_vs_WT_F09.02667.02667.2 0.0553 18-Sep R.SVNPNKPATK.D "sp|Q06787|FMR1_HUMAN,tr|A0A087WY29|A0A087WY29_HUMAN,tr|R9WNI0|R9WNI0_HUMAN,tr|A8MQB8|A8MQB8_HUMAN,tr|A0A087WXI3|A0A087WXI3_HUMAN,tr|Q8IXW7|Q8IXW7_HUMAN,tr|G3V0J0|G3V0J0_HUMAN" 7 1054.5771 2.17 124791 2667 2 1054.574354 528.2958 Synaptic functional regulator FMR1 OS=Homo sapiens OX=9606 GN=FMR1 PE=1 SV=1 10 1211.6 - 405209 - - - -2.6115 - 1.631 0.291 - 227.9 1 2 0 -0.0028 10 0 0 0 3.36E+06 1.55E+06 - - - 2.5549 0.9944 221125_WJC_METTL3_EV_vs_WT_F09.02668.02668.2 0.000835 16-Jul K.SDGHPETPK.Q "sp|Q6KC79|NIPBL_HUMAN,tr|A0A590UJS4|A0A590UJS4_HUMAN" 2 966.4407 0.94 124792 2668 2 966.436531 484.2276 Nipped-B-like protein OS=Homo sapiens OX=9606 GN=NIPBL PE=1 SV=2 5.3 1211.8 - 335598 - - - -4.2869 - 1.459 0.393 - 119.4 1 2 0 -0.0041 9 0 0 0 1.37E+07 1.47E+07 - - - 3.0353 0.9333 221125_WJC_METTL3_EV_vs_WT_F09.02671.02671.2 0.163 12-Sep K.SKDIVNK.M "sp|P52732|KIF11_HUMAN,tr|A0A7I2V3A9|A0A7I2V3A9_HUMAN" 2 802.4549 4.47 124793 2671 2 802.452054 402.2347 Kinesin-like protein KIF11 OS=Homo sapiens OX=9606 GN=KIF11 PE=1 SV=2 8.31 1212.2 - 5.70E+06 - - - -3.5067 - 1.926 0.172 - 230 1 2 1 -0.0028 7 0 0 0 4.87E+07 1.09E+07 - - - 2.3873 0.8442 221125_WJC_METTL3_EV_vs_WT_F09.02686.02686.2 0.00162 18-Aug K.SQHSGNAQVT.Q "sp|Q92499|DDX1_HUMAN,tr|A0A7I2V2M5|A0A7I2V2M5_HUMAN,tr|A0A087X2G1|A0A087X2G1_HUMAN,tr|A0A7I2V430|A0A7I2V430_HUMAN,tr|A0A7I2V421|A0A7I2V421_HUMAN,tr|A0A7I2V4F0|A0A7I2V4F0_HUMAN,tr|A0A7I2V5X8|A0A7I2V5X8_HUMAN,tr|A0A7I2V4J3|A0A7I2V4J3_HUMAN,tr|A0A087WZ71|A0A087WZ71_HUMAN,tr|A0A7I2YQ77|A0A7I2YQ77_HUMAN" 10 1027.4683 - 124807 2686 2 1027.465137 514.7414 ATP-dependent RNA helicase DDX1 OS=Homo sapiens OX=9606 GN=DDX1 PE=1 SV=2 6.46 1213.8 - 272874 - - - -3.0648 - 1.533 0.342 - 215.2 1 1 0 -0.0031 10 0 0 0 - - - - - 2.7585 0.9989 221125_WJC_METTL3_EV_vs_WT_F09.02690.02690.2 9.30E-05 18-Oct K.STNSSDVSAK.S sp|O75717|WDHD1_HUMAN 1 994.4567 0.62 124809 2690 2 994.452635 498.2356 WD repeat and HMG-box DNA-binding protein 1 OS=Homo sapiens OX=9606 GN=WDHD1 PE=1 SV=1 5.55 1214.3 - 814990 - - - -4.1058 - 1.929 0.566 - 490.8 1 2 0 -0.0041 10 0 0 0 8.24E+06 1.33E+07 - - - 5.0541 0.9664 221125_WJC_METTL3_EV_vs_WT_F09.02693.02693.2 0.0366 16-May R.NSDPNDPNR.E "sp|Q96SB4|SRPK1_HUMAN,tr|H3BLV9|H3BLV9_HUMAN" 2 1027.4319 0.35 124812 2693 2 1027.429572 514.7232 SRSF protein kinase 1 OS=Homo sapiens OX=9606 GN=SRPK1 PE=1 SV=2 4.21 1214.7 - 302880 - - - -2.2658 - 1.198 0.118 - 110.5 1 2 0 -0.0023 9 0 0 0 4.56E+06 1.29E+07 - - - 0.4345 0.9715 221125_WJC_METTL3_EV_vs_WT_F09.02705.02705.2 0.306 12-May K.HQGYTER[166.11].S "sp|Q9NUQ7|UFSP2_HUMAN,tr|H0Y9B0|H0Y9B0_HUMAN,tr|D6RGX2|D6RGX2_HUMAN,tr|H0YA18|H0YA18_HUMAN" 4 899.4125 0.8 124821 2705 2 899.410738 450.7135 Ufm1-specific protease 2 OS=Homo sapiens OX=9606 GN=UFSP2 PE=1 SV=3 6.75 1216.2 - 620090 - - - -1.9579 - 1.015 0.178 - 63.6 1 2 0 -0.0018 7 0 0 0 1.87E+07 2.34E+07 - - - 0.4023 0.9926 221125_WJC_METTL3_EV_vs_WT_F09.02707.02707.2 0.00186 18-Aug R.LQEDTDKANK.Q sp|P12270|TPR_HUMAN 1 1160.5673 5.14 124823 2707 2 1160.565456 581.2909 Nucleoprotein TPR OS=Homo sapiens OX=9606 GN=TPR PE=1 SV=3 4.56 1216.4 - 183763 - - - -1.6156 - 1.731 0.363 - 199.6 1 2 1 -0.0019 10 0 0 0 5.22E+06 1.01E+06 - - - 3.2531 0.9077 221125_WJC_METTL3_EV_vs_WT_F09.02709.02709.2 4.72 12-Jun K.DISENK[136.11]R[166.11].A "sp|P11142|HSP7C_HUMAN,sp|Q13029|PRDM2_HUMAN,tr|E9PNE6|E9PNE6_HUMAN,tr|A8K7Q2|A8K7Q2_HUMAN,tr|E9PKE3|E9PKE3_HUMAN,tr|E9PN89|E9PN89_HUMAN" 6 878.4577 0.16 124824 2709 2 878.455215 440.2361 Heat shock cognate 71 kDa protein OS=Homo sapiens OX=9606 GN=HSPA8 PE=1 SV=1 6.07 1216.7 - 5.12E+06 - - - -2.789 - 1.144 0.071 - 119.9 1 2 0 -0.0024 7 0 0 0 5.41E+07 3.48E+08 - - - -0.0091 0.9975 221125_WJC_METTL3_EV_vs_WT_F09.02716.02716.3 0.00108 Oct-36 R.LQEDTDKANK.Q sp|P12270|TPR_HUMAN 1 1160.5673 3.75 124828 2716 3 1160.563532 387.8631 Nucleoprotein TPR OS=Homo sapiens OX=9606 GN=TPR PE=1 SV=3 4.56 1217.4 - 2.84E+06 - - - -3.2734 - 2.088 0.401 - 71.5 2 2 1 -0.0038 10 0 0 0 3.65E+07 9.72E+06 - - - 5.0204 0.9726 221125_WJC_METTL3_EV_vs_WT_F09.02717.02717.2 0.307 12-Jun K.HQGYTER.S "sp|Q9NUQ7|UFSP2_HUMAN,tr|H0Y9B0|H0Y9B0_HUMAN,tr|D6RGX2|D6RGX2_HUMAN,tr|H0YA18|H0YA18_HUMAN" 4 889.4042 0.86 124829 2717 2 889.401493 445.7094 Ufm1-specific protease 2 OS=Homo sapiens OX=9606 GN=UFSP2 PE=1 SV=3 6.75 1217.4 - 1.40E+06 - - - -3.0762 - 1.242 0.17 - 106.5 1 2 0 -0.0027 7 0 0 0 1.87E+07 2.16E+07 - - - 0.9825 0.9965 221125_WJC_METTL3_EV_vs_WT_F09.02724.02724.2 0.0109 20-May R.NTGSC[160.03]QEAAAK[136.11].V "sp|O15270|SPTC2_HUMAN,tr|H0YJV2|H0YJV2_HUMAN" 2 1143.507 0.47 124834 2724 2 1143.502392 572.7608 Serine palmitoyltransferase 2 OS=Homo sapiens OX=9606 GN=SPTLC2 PE=1 SV=1 5.99 1218.3 - 155297 - - - -4.0175 - 1.509 0.432 - 85.2 1 2 0 -0.0046 11 0 0 0 3.37E+06 7.19E+06 - - - 3.3434 0.9991 221125_WJC_METTL3_EV_vs_WT_F09.02730.02730.2 0.00126 12-Jul R.HYDDPGK.G sp|P55316|FOXG1_HUMAN 1 830.3559 0.95 124838 2730 2 830.353594 416.1852 Forkhead box protein G1 OS=Homo sapiens OX=9606 GN=FOXG1 PE=1 SV=2 5.21 1219.1 - 375761 - - - -2.7554 - 1.43 0.494 - 273.6 1 2 0 -0.0023 7 0 0 0 7.70E+06 8.15E+06 - - - 3.8223 0.9987 221125_WJC_METTL3_EV_vs_WT_F09.02736.02736.2 0.000736 12-Jul R.HYDDPGK[136.11].G sp|P55316|FOXG1_HUMAN 1 838.3701 0.95 124842 2736 2 838.367762 420.1923 Forkhead box protein G1 OS=Homo sapiens OX=9606 GN=FOXG1 PE=1 SV=2 5.21 1219.9 - 449342 - - - -2.7673 - 1.338 0.465 - 279.7 1 2 0 -0.0023 7 0 0 0 7.70E+06 8.09E+06 - - - 3.3974 0.9984 221125_WJC_METTL3_EV_vs_WT_F09.02742.02742.3 0.0005 Nov-44 K.VADSSKGPDEAK.L "sp|O60506|HNRPQ_HUMAN,tr|A0A7I2YQV8|A0A7I2YQV8_HUMAN,tr|A0A7I2YQN2|A0A7I2YQN2_HUMAN,tr|A0A7I2V5Q6|A0A7I2V5Q6_HUMAN,tr|A0A7I2V4Z0|A0A7I2V4Z0_HUMAN,tr|B7Z645|B7Z645_HUMAN,tr|A0A7I2V2F0|A0A7I2V2F0_HUMAN,tr|A0A7I2V2F2|A0A7I2V2F2_HUMAN,tr|A0A7I2V4J0|A0A7I2V4J0_HUMAN,tr|F6UXX1|F6UXX1_HUMAN,tr|A0A7I2V346|A0A7I2V346_HUMAN,tr|A0A7I2V309|A0A7I2V309_HUMAN" 12 1202.5779 1.22 124846 2742 3 1202.574738 401.8666 Heterogeneous nuclear ribonucleoprotein Q OS=Homo sapiens OX=9606 GN=SYNCRIP PE=1 SV=2 4.56 1220.7 - 488484 - - - -2.626 - 2.399 0.363 - 132.7 1 2 1 -0.0032 12 0 0 0 3.58E+07 2.92E+07 - - - 5.0117 0.9953 221125_WJC_METTL3_EV_vs_WT_F09.02744.02744.2 0.42 14-Jul R.RSSSDIAR.A "sp|P78364|PHC1_HUMAN,tr|J3KQH6|J3KQH6_HUMAN" 2 890.457 999 124848 2744 2 890.456881 446.2358 Polyhomeotic-like protein 1 OS=Homo sapiens OX=9606 GN=PHC1 PE=1 SV=3 9.6 1220.9 - 664317 - - - -0.1258 - 1.374 0.172 - 108.8 2 2 0 -0.0001 8 0 0 0 7.24E+06 0.00E+00 - - - 1.1351 0.9997 221125_WJC_METTL3_EV_vs_WT_F09.02745.02745.2 0.0148 18-Sep K.AQGQEQEQER[166.11].Q sp|Q96BH1|RNF25_HUMAN 1 1211.5406 1.05 124849 2745 2 1211.537708 606.7776 E3 ubiquitin-protein ligase RNF25 OS=Homo sapiens OX=9606 GN=RNF25 PE=1 SV=1 4.25 1221 - 273007 - - - -2.3978 - 1.982 0.537 - 374.3 1 2 0 -0.0029 10 0 0 0 2.49E+06 2.37E+06 - - - 4.9159 0.9935 221125_WJC_METTL3_EV_vs_WT_F09.02747.02747.2 0.00227 18-Sep R.AETEQGEQQR.Q sp|Q15149|PLEC_HUMAN 1 1174.5214 1.94 124851 2747 2 1174.513648 588.268 Plectin OS=Homo sapiens OX=9606 GN=PLEC PE=1 SV=3 4.25 1221.3 - 136354 - - - -6.6376 - 2.248 0.506 - 393.6 1 2 0 -0.0078 10 0 0 0 5.26E+06 2.71E+06 - - - 5.0369 0.846 221125_WJC_METTL3_EV_vs_WT_F09.02751.02751.2 11.6 14-Jun K.EEKPSVSK.E "sp|O43491|E41L2_HUMAN,tr|E9PIG0|E9PIG0_HUMAN,tr|A0A2R8Y5B3|A0A2R8Y5B3_HUMAN,tr|E9PII3|E9PII3_HUMAN,tr|E9PHY5|E9PHY5_HUMAN,tr|E9PK52|E9PK52_HUMAN,tr|E9PRG1|E9PRG1_HUMAN,tr|E9PQD2|E9PQD2_HUMAN" 8 902.4709 0.77 124853 2751 2 902.468448 452.2427 Band 4.1-like protein 2 OS=Homo sapiens OX=9606 GN=EPB41L2 PE=1 SV=1 6.24 1221.8 - 456378 - - - -2.7303 - 1.042 0.059 - 110.7 1 2 0 -0.0025 8 0 0 0 4.39E+06 5.71E+06 - - - -0.3999 0.9974 221125_WJC_METTL3_EV_vs_WT_F09.02753.02753.2 0.12 16-Aug K.QTK[136.11]PAEAPR[166.11].L "sp|Q14690|RRP5_HUMAN,tr|A0A3B3IUD7|A0A3B3IUD7_HUMAN" 2 1014.5577 1.24 124855 2753 2 1014.558993 508.2861 Protein RRP5 homolog OS=Homo sapiens OX=9606 GN=PDCD11 PE=1 SV=3 8.75 1222.1 - 292292 - - - 1.2616 - 1.378 0.264 - 220.1 1 2 0 0.0013 9 0 0 0 3.93E+06 3.18E+06 - - - 1.9181 0.9998 221125_WJC_METTL3_EV_vs_WT_F09.02754.02754.2 0.00987 18-Sep R.AETEQGEQQR[166.11].Q sp|Q15149|PLEC_HUMAN 1 1184.5297 1.94 124856 2754 2 1184.528622 593.2721 Plectin OS=Homo sapiens OX=9606 GN=PLEC PE=1 SV=3 4.25 1222.2 - 161079 - - - -0.9219 - 1.858 0.504 - 280.7 1 2 0 -0.0011 10 0 0 0 5.26E+06 2.71E+06 - - - 4.4924 0.9994 221125_WJC_METTL3_EV_vs_WT_F09.02761.02761.2 0.000543 22-Jul R.GAAATTTTTEHR[166.11].F "sp|Q9H4A3|WNK1_HUMAN,tr|F5GWT4|F5GWT4_HUMAN,tr|F6UYG0|F6UYG0_HUMAN" 3 1225.5926 1.55 124861 2761 2 1225.589985 613.8036 Serine\threonine-protein kinase WNK1 OS=Homo sapiens OX=9606 GN=WNK1 PE=1 SV=2 6.75 1223.1 - 83690.7 - - - -2.1728 - 1.769 0.457 - 183.4 1 2 0 -0.0027 12 0 0 0 3.29E+06 2.11E+06 - - - 3.9164 0.9999 221125_WJC_METTL3_EV_vs_WT_F09.02764.02764.3 0.00101 14/44 R.GAAATTTTTEHR.F "sp|Q9H4A3|WNK1_HUMAN,tr|F5GWT4|F5GWT4_HUMAN,tr|F6UYG0|F6UYG0_HUMAN" 3 1215.5844 3.18 124862 2764 3 1215.581237 406.2021 Serine\threonine-protein kinase WNK1 OS=Homo sapiens OX=9606 GN=WNK1 PE=1 SV=2 6.75 1223.5 - 1.65E+06 - - - -2.5839 - 2.576 0.421 - 335.4 1 2 0 -0.0031 12 0 0 0 4.77E+07 1.50E+07 - - - 5.8557 0.9999 221125_WJC_METTL3_EV_vs_WT_F09.02765.02765.3 1.47E-05 17/44 R.GAAATTTTTEHR[166.11].F "sp|Q9H4A3|WNK1_HUMAN,tr|F5GWT4|F5GWT4_HUMAN,tr|F6UYG0|F6UYG0_HUMAN" 3 1225.5926 3.31 124863 2765 3 1225.588793 409.5382 Serine\threonine-protein kinase WNK1 OS=Homo sapiens OX=9606 GN=WNK1 PE=1 SV=2 6.75 1223.6 - 1.14E+06 - - - -3.1454 - 2.873 0.499 - 567.8 1 2 0 -0.0039 12 0 0 0 4.53E+07 1.37E+07 - - - 7.0276 0.9992 221125_WJC_METTL3_EV_vs_WT_F09.02766.02766.2 0.00633 14-Aug R.RSDAGSYR.R sp|Q8WUF5|IASPP_HUMAN 1 910.4257 4.73 124864 2766 2 910.424 456.2201 RelA-associated inhibitor OS=Homo sapiens OX=9606 GN=PPP1R13L PE=1 SV=4 8.75 1223.7 - 878231 - - - -1.8596 - 1.666 0.362 - 159.7 1 2 0 -0.0017 8 0 0 0 1.08E+07 2.28E+06 - - - 3.2536 0.9997 221125_WJC_METTL3_EV_vs_WT_F09.02768.02768.2 6.60E-05 22-Oct R.GAAATTTTTEHR.F "sp|Q9H4A3|WNK1_HUMAN,tr|F5GWT4|F5GWT4_HUMAN,tr|F6UYG0|F6UYG0_HUMAN" 3 1215.5844 1.55 124866 2768 2 1215.581707 608.7995 Serine\threonine-protein kinase WNK1 OS=Homo sapiens OX=9606 GN=WNK1 PE=1 SV=2 6.75 1224 - 228129 - - - -2.1973 - 2.317 0.464 - 360.1 1 2 0 -0.0027 12 0 0 0 3.29E+06 2.11E+06 - - - 4.6782 0.9998 221125_WJC_METTL3_EV_vs_WT_F09.02769.02769.2 0.000599 18-Sep R.SAVNTEEEKK.S sp|Q16706|MA2A1_HUMAN 1 1133.5564 0.83 124867 2769 2 1133.555409 567.7855 Alpha-mannosidase 2 OS=Homo sapiens OX=9606 GN=MAN2A1 PE=1 SV=2 4.78 1224.1 - 179456 - - - -0.9025 - 1.819 0.449 - 281 1 2 0 -0.001 10 0 0 0 2.00E+06 2.42E+06 - - - 4.027 0.9993 221125_WJC_METTL3_EV_vs_WT_F09.02775.02775.2 0.00014 18-Sep R.SAVNTEEEK[136.11]K[136.11].S sp|Q16706|MA2A1_HUMAN 1 1149.5848 0.83 124871 2775 2 1149.582253 575.7997 Alpha-mannosidase 2 OS=Homo sapiens OX=9606 GN=MAN2A1 PE=1 SV=2 4.78 1224.9 - 270675 - - - -2.2434 - 1.867 0.402 - 352.6 1 2 0 -0.0026 10 0 0 0 2.00E+06 2.42E+06 - - - 3.7521 0.9998 221125_WJC_METTL3_EV_vs_WT_F09.02778.02778.2 5.75E-08 13/26 K.AGGEGGSEEEGSDK.G "sp|P07197|NFM_HUMAN,tr|E7ESP9|E7ESP9_HUMAN" 2 1307.5113 4.99 124874 2778 2 1307.509352 654.7629 Neurofilament medium polypeptide OS=Homo sapiens OX=9606 GN=NEFM PE=1 SV=3 3.91 1225.3 - 173562 - - - -1.5151 - 2.601 0.469 - 586 1 2 0 -0.002 14 0 0 0 1.33E+06 2.66E+05 - - - 4.9032 0.9996 221125_WJC_METTL3_EV_vs_WT_F09.02789.02789.2 0.000743 14-Jun R.DHGDMTNR.K "sp|Q6P2Q9|PRP8_HUMAN,tr|I3L0J9|I3L0J9_HUMAN" 2 944.377 0.73 124883 2789 2 944.375305 473.1958 Pre-mRNA-processing-splicing factor 8 OS=Homo sapiens OX=9606 GN=PRPF8 PE=1 SV=2 5.21 1226.7 - 383874 - - - -1.8245 - 1.413 0.534 - 154.8 1 2 0 -0.0017 8 0 0 0 3.38E+06 4.64E+06 - - - 4.0272 0.97 221125_WJC_METTL3_EV_vs_WT_F09.02794.02794.2 0.0642 26-Feb K.AGGEGGSEEEGSDK[136.11].G "sp|P07197|NFM_HUMAN,tr|E7ESP9|E7ESP9_HUMAN" 2 1315.5255 -1 124888 2794 2 1315.523215 658.77 Neurofilament medium polypeptide OS=Homo sapiens OX=9606 GN=NEFM PE=1 SV=3 3.91 1227.4 - 63930 - - - -1.762 - 0.705 0.305 - 5.3 2 2 0 -0.0023 14 0 0 0 0.00E+00 0.00E+00 - - - 0.2813 0.9038 221125_WJC_METTL3_EV_vs_WT_F09.02798.02798.2 0.195 14-Sep R.QR[166.11]ESDITK[136.11].E "sp|P17987|TCPA_HUMAN,tr|F5GZ03|F5GZ03_HUMAN,tr|F5H282|F5H282_HUMAN,tr|E7EQR6|E7EQR6_HUMAN,tr|E7ERF2|E7ERF2_HUMAN" 5 993.521 0.59 124890 2798 2 993.518581 497.7678 T-complex protein 1 subunit alpha OS=Homo sapiens OX=9606 GN=TCP1 PE=1 SV=1 6.07 1227.9 - 2.68E+06 - - - -2.4277 - 1.704 0.105 - 369 1 2 1 -0.0024 8 0 0 0 4.56E+07 7.74E+07 - - - 1.4232 0.9993 221125_WJC_METTL3_EV_vs_WT_F09.02799.02799.2 0.00562 16-Sep K.EALNSC[160.03]NK[136.11]R[166.11].E "sp|P19338|NUCL_HUMAN,tr|A0A7I2V506|A0A7I2V506_HUMAN,tr|A0A7I2V699|A0A7I2V699_HUMAN,tr|A0A7I2V2U7|A0A7I2V2U7_HUMAN,tr|A0A7I2V3F3|A0A7I2V3F3_HUMAN,tr|A0A7I2V428|A0A7I2V428_HUMAN,tr|A0A7I2V349|A0A7I2V349_HUMAN,tr|H7BY16|H7BY16_HUMAN,tr|A0A7I2V5M5|A0A7I2V5M5_HUMAN,tr|C9JLB1|C9JLB1_HUMAN" 10 1108.5414 0.92 124891 2799 2 1108.538141 555.278 Nucleolin OS=Homo sapiens OX=9606 GN=NCL PE=1 SV=3 8.32 1228 - 2.33E+06 - - - -2.9507 - 1.883 0.48 - 372.9 1 2 0 -0.0033 9 0 0 0 4.04E+07 4.39E+07 - - - 4.4162 0.9917 221125_WJC_METTL3_EV_vs_WT_F09.02801.02801.2 0.00186 14/20 K.TK[136.11]QGVAEAAGK[136.11].T "sp|P37840|SYUA_HUMAN,tr|A0A669KB41|A0A669KB41_HUMAN,tr|D6RA31|D6RA31_HUMAN,tr|A0A669KBH5|A0A669KBH5_HUMAN,tr|H6UYS7|H6UYS7_HUMAN,tr|E7EPV7|E7EPV7_HUMAN" 6 1074.6004 0.7 124893 2801 2 1074.596523 538.3075 Alpha-synuclein OS=Homo sapiens OX=9606 GN=SNCA PE=1 SV=1 8.26 1228.2 - 1.70E+06 - - - -3.6293 - 2.538 0.483 - 467.6 1 2 1 -0.0039 11 0 0 0 1.30E+07 1.87E+07 - - - 5.1268 0.9941 221125_WJC_METTL3_EV_vs_WT_F09.02805.02805.2 0.0111 16-Sep R.QLQQQQQQK.V sp|Q15911|ZFHX3_HUMAN 1 1155.5996 2.2 124896 2805 2 1155.596264 578.8071 Zinc finger homeobox protein 3 OS=Homo sapiens OX=9606 GN=ZFHX3 PE=1 SV=2 8.75 1228.5 - 531357 - - - -2.9171 - 1.595 0.228 - 382.2 1 2 0 -0.0034 9 0 0 0 2.75E+06 1.25E+06 - - - 2.0746 0.8237 221125_WJC_METTL3_EV_vs_WT_F09.02806.02806.2 0.0662 16-Aug K.IQAQEDREK.G "sp|Q9Y3D7|TIM16_HUMAN,tr|I3L3T0|I3L3T0_HUMAN,tr|A0A0A6YYL4|A0A0A6YYL4_HUMAN,tr|I3L0X9|I3L0X9_HUMAN" 4 1115.5571 2.38 124897 2806 2 1115.55259 558.7858 Mitochondrial import inner membrane translocase subunit TIM16 OS=Homo sapiens OX=9606 GN=PAM16 PE=1 SV=2 4.68 1228.7 - 432701 - - - -4.0437 - 1.554 0.201 - 203 1 2 1 -0.0045 9 0 0 0 3.18E+06 1.34E+06 - - - 1.7995 0.8721 221125_WJC_METTL3_EV_vs_WT_F09.02818.02818.2 0.0341 16-Jul R.K[136.11]ISSPTGSK[136.11].D "sp|Q99623|PHB2_HUMAN,tr|A0A7I2V5F0|A0A7I2V5F0_HUMAN,tr|F5GWA7|F5GWA7_HUMAN,tr|J3KPX7|J3KPX7_HUMAN,tr|F5GY37|F5GY37_HUMAN" 5 919.5309 1.13 124906 2818 2 919.524469 460.7727 Prohibitin-2 OS=Homo sapiens OX=9606 GN=PHB2 PE=1 SV=2 10 1230.2 - 554525 - - - -7.0438 - 1.562 0.205 - 139.7 1 2 0 -0.0065 9 0 0 0 1.55E+08 1.38E+08 - - - 1.8433 0.9956 221125_WJC_METTL3_EV_vs_WT_F09.02823.02823.2 0.0108 16-Sep K.EALNSC[160.03]NKR.E "sp|P19338|NUCL_HUMAN,tr|A0A7I2V506|A0A7I2V506_HUMAN,tr|A0A7I2V699|A0A7I2V699_HUMAN,tr|A0A7I2V2U7|A0A7I2V2U7_HUMAN,tr|A0A7I2V3F3|A0A7I2V3F3_HUMAN,tr|A0A7I2V428|A0A7I2V428_HUMAN,tr|A0A7I2V349|A0A7I2V349_HUMAN,tr|H7BY16|H7BY16_HUMAN,tr|A0A7I2V5M5|A0A7I2V5M5_HUMAN,tr|C9JLB1|C9JLB1_HUMAN" 10 1090.5189 0.9 124910 2823 2 1090.513777 546.2667 Nucleolin OS=Homo sapiens OX=9606 GN=NCL PE=1 SV=3 8.32 1230.7 - 5.55E+06 - - - -4.7363 - 1.832 0.388 - 370.3 1 2 0 -0.0052 9 0 0 0 3.94E+07 4.39E+07 - - - 3.6566 0.9951 221125_WJC_METTL3_EV_vs_WT_F09.02824.02824.2 0.00656 16-Oct R.QLQEEQEKK.A sp|Q9NQS7|INCE_HUMAN 1 1158.5881 1.62 124911 2824 2 1158.583549 580.3013 Inner centromere protein OS=Homo sapiens OX=9606 GN=INCENP PE=1 SV=3 4.79 1230.8 - 1.33E+06 - - - -3.8996 - 1.841 0.284 - 466.6 1 2 0 -0.0045 9 0 0 0 6.46E+06 3.99E+06 - - - 2.9029 0.898 221125_WJC_METTL3_EV_vs_WT_F09.02833.02833.2 6.99E-05 22-Nov S.VSSSSTASASAK.K "sp|Q16836|HCDH_HUMAN,tr|A0A804HJW7|A0A804HJW7_HUMAN,tr|A0A1W2PP40|A0A1W2PP40_HUMAN,tr|E9PF18|E9PF18_HUMAN,tr|A0A0A0MSE2|A0A0A0MSE2_HUMAN,tr|A0A1W2PQV5|A0A1W2PQV5_HUMAN,tr|J3KR89|J3KR89_HUMAN,tr|A0A1W2PNM1|A0A1W2PNM1_HUMAN,tr|A0A1W2PQ78|A0A1W2PQ78_HUMAN" 9 1081.5251 2.58 124917 2833 2 1081.520044 541.7698 "Hydroxyacyl-coenzyme A dehydrogenase, mitochondrial OS=Homo sapiens OX=9606 GN=HADH PE=1 SV=3" 8.72 1231.9 - 705574 - - - -4.7045 - 2.073 0.527 - 425.4 1 1 0 -0.0051 12 0 0 0 1.71E+07 6.63E+06 - - - 4.8499 0.9885 221125_WJC_METTL3_EV_vs_WT_F09.02844.02844.2 0.441 12-Aug K.K[136.11]QEELNR[166.11].K sp|O14828|SCAM3_HUMAN 1 933.4999 1.23 124922 2844 2 933.496 467.7572 Secretory carrier-associated membrane protein 3 OS=Homo sapiens OX=9606 GN=SCAMP3 PE=1 SV=3 6.14 1233.3 - 3.83E+06 - - - -4.1393 - 1.794 0.186 - 275.8 1 2 0 -0.0039 7 0 0 0 4.86E+07 3.95E+07 - - - 2.2654 0.9992 221125_WJC_METTL3_EV_vs_WT_F09.02845.02845.2 0.000333 14-Aug R.SYSPAHNR.E "sp|Q9Y2W1|TR150_HUMAN,tr|A0A3B3ITZ9|A0A3B3ITZ9_HUMAN" 2 930.4308 2.29 124923 2845 2 930.42866 466.2227 Thyroid hormone receptor-associated protein 3 OS=Homo sapiens OX=9606 GN=THRAP3 PE=1 SV=2 8.49 1233.5 - 1.15E+06 - - - -2.2764 - 1.449 0.455 - 264.6 1 2 0 -0.0021 8 0 0 0 6.39E+08 2.79E+08 - - - 3.5195 0.9995 221125_WJC_METTL3_EV_vs_WT_F09.02847.02847.2 4.89E-05 13/16 R.HLQEAEQTK[136.11].N sp|Q96P70|IPO9_HUMAN 1 1090.5498 2.21 124925 2847 2 1090.547139 546.2822 Importin-9 OS=Homo sapiens OX=9606 GN=IPO9 PE=1 SV=3 5.4 1233.7 - 464018 - - - -2.474 - 2.127 0.426 - 514.9 1 2 0 -0.0027 9 0 0 0 1.45E+07 6.55E+06 - - - 4.37 0.9483 221125_WJC_METTL3_EV_vs_WT_F09.02850.02850.2 2.98E-05 13/20 L.SSGTQAVSGSK.D "sp|Q9BQA1|MEP50_HUMAN,tr|H0Y711|H0Y711_HUMAN" 2 1007.4884 2.92 124926 2850 2 1007.484124 504.7515 Methylosome protein 50 OS=Homo sapiens OX=9606 GN=WDR77 PE=1 SV=1 8.47 1234.1 - 1.78E+06 - - - -4.1976 - 2.525 0.553 - 757.8 1 1 0 -0.0042 11 0 0 0 5.67E+07 1.94E+07 - - - 5.6298 0.9815 221125_WJC_METTL3_EV_vs_WT_F09.02852.02852.2 2.46 14-Jul R.AQEDEVK[136.11]R[166.11].L "sp|Q8WVM8|SCFD1_HUMAN,tr|A0A7I2V4U2|A0A7I2V4U2_HUMAN,tr|A0A7I2V4B8|A0A7I2V4B8_HUMAN,tr|H0YIZ7|H0YIZ7_HUMAN,tr|A0A7I2V5Z4|A0A7I2V5Z4_HUMAN,tr|A0A7I2V3C9|A0A7I2V3C9_HUMAN,tr|B7Z5N7|B7Z5N7_HUMAN,tr|A0A7I2V5I2|A0A7I2V5I2_HUMAN,tr|A0A7I2V590|A0A7I2V590_HUMAN,tr|G3V5E2|G3V5E2_HUMAN,tr|A0A7I2V2U5|A0A7I2V2U5_HUMAN,tr|A0A7I2YQR2|A0A7I2YQR2_HUMAN,tr|A0A7I2V362|A0A7I2V362_HUMAN,tr|A0A7I2V448|A0A7I2V448_HUMAN,tr|A0A7I2V320|A0A7I2V320_HUMAN,tr|A0A7I2V534|A0A7I2V534_HUMAN,tr|A0A7I2V3G4|A0A7I2V3G4_HUMAN,tr|A0A7I2V3B4|A0A7I2V3B4_HUMAN,tr|A0A7I2V5H5|A0A7I2V5H5_HUMAN,tr|A0A7I2V4R0|A0A7I2V4R0_HUMAN" 20 991.5053 0.55 124928 2852 2 991.500923 496.7599 Sec1 family domain-containing protein 1 OS=Homo sapiens OX=9606 GN=SCFD1 PE=1 SV=4 4.68 1234.2 - 1.41E+06 - - - -4.4579 - 1.562 0.226 - 293.3 1 2 0 -0.0044 8 0 0 0 4.78E+07 8.74E+07 - - - 2.0539 0.9363 221125_WJC_METTL3_EV_vs_WT_F09.02853.02853.2 0.417 14-Aug R.AQEDEVKR.L "sp|Q8WVM8|SCFD1_HUMAN,tr|A0A7I2V4U2|A0A7I2V4U2_HUMAN,tr|A0A7I2V4B8|A0A7I2V4B8_HUMAN,tr|H0YIZ7|H0YIZ7_HUMAN,tr|A0A7I2V5Z4|A0A7I2V5Z4_HUMAN,tr|A0A7I2V3C9|A0A7I2V3C9_HUMAN,tr|B7Z5N7|B7Z5N7_HUMAN,tr|A0A7I2V5I2|A0A7I2V5I2_HUMAN,tr|A0A7I2V590|A0A7I2V590_HUMAN,tr|G3V5E2|G3V5E2_HUMAN,tr|A0A7I2V2U5|A0A7I2V2U5_HUMAN,tr|A0A7I2YQR2|A0A7I2YQR2_HUMAN,tr|A0A7I2V362|A0A7I2V362_HUMAN,tr|A0A7I2V448|A0A7I2V448_HUMAN,tr|A0A7I2V320|A0A7I2V320_HUMAN,tr|A0A7I2V534|A0A7I2V534_HUMAN,tr|A0A7I2V3G4|A0A7I2V3G4_HUMAN,tr|A0A7I2V3B4|A0A7I2V3B4_HUMAN,tr|A0A7I2V5H5|A0A7I2V5H5_HUMAN,tr|A0A7I2V4R0|A0A7I2V4R0_HUMAN" 20 973.4829 0.54 124929 2853 2 973.476869 487.7487 Sec1 family domain-containing protein 1 OS=Homo sapiens OX=9606 GN=SCFD1 PE=1 SV=4 4.68 1234.3 - 1.30E+06 - - - -6.1675 - 1.758 0.17 - 395.8 1 2 0 -0.006 8 0 0 0 4.77E+07 8.78E+07 - - - 1.9963 0.9983 221125_WJC_METTL3_EV_vs_WT_F09.02854.02854.2 0.000871 14-Aug R.SYSPAHNR[166.11].E "sp|Q9Y2W1|TR150_HUMAN,tr|A0A3B3ITZ9|A0A3B3ITZ9_HUMAN" 2 940.439 2.29 124930 2854 2 940.435784 471.2268 Thyroid hormone receptor-associated protein 3 OS=Homo sapiens OX=9606 GN=THRAP3 PE=1 SV=2 8.49 1234.4 - 882648 - - - -3.4707 - 1.539 0.453 - 255.5 1 2 0 -0.0033 8 0 0 0 6.39E+08 2.79E+08 - - - 3.6861 0.9712 221125_WJC_METTL3_EV_vs_WT_F09.02855.02855.2 7.54E-05 20-Oct L.SSGTQAVSGSK[136.11].D "sp|Q9BQA1|MEP50_HUMAN,tr|H0Y711|H0Y711_HUMAN" 2 1015.5026 2.92 124931 2855 2 1015.499852 508.7586 Methylosome protein 50 OS=Homo sapiens OX=9606 GN=WDR77 PE=1 SV=1 8.47 1234.6 - 852519 - - - -2.6598 - 2.124 0.475 - 431.7 1 1 0 -0.0027 11 0 0 0 5.67E+07 1.94E+07 - - - 4.5864 0.9993 221125_WJC_METTL3_EV_vs_WT_F09.02860.02860.2 0.000131 16-Dec R.K[136.11]SSTPEEVK[136.11].K "sp|P23528|COF1_HUMAN,tr|E9PP50|E9PP50_HUMAN,tr|G3V1A4|G3V1A4_HUMAN,tr|E9PQB7|E9PQB7_HUMAN,tr|E9PK25|E9PK25_HUMAN,tr|E9PLJ3|E9PLJ3_HUMAN,tr|E9PS23|E9PS23_HUMAN" 7 1019.547 1.39 124934 2860 2 1019.543213 510.7808 Cofilin-1 OS=Homo sapiens OX=9606 GN=CFL1 PE=1 SV=3 6.14 1235.2 - 666409 - - - -3.7046 - 2.476 0.495 - 430.2 1 2 0 -0.0038 9 0 0 0 5.35E+08 3.86E+08 - - - 5.3189 0.9996 221125_WJC_METTL3_EV_vs_WT_F09.02861.02861.3 0.0015 Nov-40 K.MENDESAKEEK.S "sp|Q9P2K5|MYEF2_HUMAN,tr|A0A0A0MR39|A0A0A0MR39_HUMAN,tr|A0A087WUT0|A0A087WUT0_HUMAN,tr|A0A087WWC8|A0A087WWC8_HUMAN,tr|A0A0A0MQW0|A0A0A0MQW0_HUMAN" 5 1308.5504 1.32 124935 2861 3 1308.546329 437.1907 Myelin expression factor 2 OS=Homo sapiens OX=9606 GN=MYEF2 PE=1 SV=3 4.25 1235.4 - 399509 - - - -3.0813 - 2.218 0.554 - 148.6 1 2 1 -0.004 11 0 0 0 4.18E+06 3.16E+06 - - - 6.9785 0.8612 221125_WJC_METTL3_EV_vs_WT_F09.02862.02862.2 8.52 12-Jun S.YSPAHNR[166.11].E "sp|Q9Y2W1|TR150_HUMAN,tr|A0A3B3ITZ9|A0A3B3ITZ9_HUMAN" 2 853.407 2.3 124936 2862 2 853.407035 427.7108 Thyroid hormone receptor-associated protein 3 OS=Homo sapiens OX=9606 GN=THRAP3 PE=1 SV=2 8.75 1235.5 - 298176 - - - 0.0176 - 1.037 0.326 - 189.7 1 1 0 0 7 0 0 0 1.58E+08 6.87E+07 - - - 1.564 0.9932 221125_WJC_METTL3_EV_vs_WT_F09.02865.02865.2 1.27 12-Jul K.KQEELNR.K sp|O14828|SCAM3_HUMAN 1 915.4774 1.23 124938 2865 2 915.474873 458.746 Secretory carrier-associated membrane protein 3 OS=Homo sapiens OX=9606 GN=SCAMP3 PE=1 SV=3 6.14 1235.9 - 2.93E+06 - - - -2.7538 - 1.706 0.153 - 204.2 1 2 0 -0.0025 7 0 0 0 4.86E+07 3.95E+07 - - - 1.8628 0.9938 221125_WJC_METTL3_EV_vs_WT_F09.02878.02878.2 0.0814 12-Jul K.SIQHHLR.T "sp|Q9NP79|VTA1_HUMAN,tr|A0A087WY55|A0A087WY55_HUMAN" 2 889.4882 1.28 124948 2878 2 889.486439 445.7514 Vacuolar protein sorting-associated protein VTA1 homolog OS=Homo sapiens OX=9606 GN=VTA1 PE=1 SV=1 9.51 1237.4 - 794318 - - - -2.018 - 1.256 0.237 - 239 1 2 0 -0.0018 7 0 0 0 1.91E+07 1.50E+07 - - - 1.5131 0.9997 221125_WJC_METTL3_EV_vs_WT_F09.02886.02886.2 0.17 16-Nov R.KSSTPEEVK.K "sp|P23528|COF1_HUMAN,tr|E9PP50|E9PP50_HUMAN,tr|G3V1A4|G3V1A4_HUMAN,tr|E9PQB7|E9PQB7_HUMAN,tr|E9PK25|E9PK25_HUMAN,tr|E9PLJ3|E9PLJ3_HUMAN,tr|E9PS23|E9PS23_HUMAN" 7 1003.5186 1.39 124954 2886 2 1003.516408 502.7666 Cofilin-1 OS=Homo sapiens OX=9606 GN=CFL1 PE=1 SV=3 6.14 1238.4 - 9.01E+06 - - - -2.1743 - 2.269 0.446 - 347.1 1 2 0 -0.0022 9 0 0 0 5.35E+08 3.86E+08 - - - 4.7049 0.9483 221125_WJC_METTL3_EV_vs_WT_F09.02887.02887.2 0.00881 16-Jun K.DYGKESQAK.D sp|P25398|RS12_HUMAN 1 1024.4825 0.66 124955 2887 2 1024.480012 513.2485 40S ribosomal protein S12 OS=Homo sapiens OX=9606 GN=RPS12 PE=1 SV=3 6.07 1238.6 - 829214 - - - -2.4666 - 1.257 0.325 - 76.3 2 2 1 -0.0025 9 0 0 0 4.56E+06 6.87E+06 - - - 1.9679 0.9991 221125_WJC_METTL3_EV_vs_WT_F09.02894.02894.2 0.0531 16-Jul K.TEEVDEEKK.M sp|Q9UIG0|BAZ1B_HUMAN 1 1105.5139 6.79 124960 2894 2 1105.512317 553.7642 Tyrosine-protein kinase BAZ1B OS=Homo sapiens OX=9606 GN=BAZ1B PE=1 SV=2 4.25 1239.5 - 112572 - - - -1.431 - 1.477 0.36 - 184.8 1 2 0 -0.0016 9 0 0 0 1.87E+07 2.75E+06 - - - 2.8278 0.9919 221125_WJC_METTL3_EV_vs_WT_F09.02900.02900.2 0.89 14-Sep K.KGPAAIQK.N sp|P35527|K1C9_HUMAN 1 811.4916 177.68 124964 2900 2 811.488388 406.7531 "Keratin, type I cytoskeletal 9 OS=Homo sapiens OX=9606 GN=KRT9 PE=1 SV=3" 10 1240.3 - 458940 - - - -3.9434 - 1.843 0.213 - 263.2 1 2 0 -0.0032 8 0 0 0 3.41E+07 1.92E+05 - - - 2.4572 0.8029 221125_WJC_METTL3_EV_vs_WT_F09.02906.02906.2 3.32 18-May R.RAPPGGC[160.03]EER.E sp|Q5RKV6|EXOS6_HUMAN 1 1127.5142 1.22 124968 2906 2 1127.512456 564.7644 Exosome complex component MTR3 OS=Homo sapiens OX=9606 GN=EXOSC6 PE=1 SV=1 6.14 1241.1 - 272424 - - - -1.5388 - 0.999 0.042 - 34 10 2 0 -0.0017 10 0 0 0 3.91E+06 3.20E+06 - - - -1.0988 0.9332 221125_WJC_METTL3_EV_vs_WT_F09.02910.02910.2 0.0837 14-Jul R.SK[136.11]GQESFK[136.11].K "sp|P06748|NPM_HUMAN,tr|E5RI98|E5RI98_HUMAN,tr|A0A7I2V5S2|A0A7I2V5S2_HUMAN" 3 925.484 0.75 124970 2910 2 925.480572 463.7493 Nucleophosmin OS=Homo sapiens OX=9606 GN=NPM1 PE=1 SV=2 8.31 1241.6 - 641213 - - - -3.6997 - 1.448 0.319 - 115.4 1 2 1 -0.0034 8 0 0 0 2.11E+08 2.82E+08 - - - 2.5125 0.9997 221125_WJC_METTL3_EV_vs_WT_F09.02912.02912.2 3.76E-06 20-Sep R.NADC[160.03]SSGPGQR[166.11].V "sp|Q9BSD7|NTPCR_HUMAN,tr|Q5TDF0|Q5TDF0_HUMAN" 2 1157.4759 1.18 124972 2912 2 1157.474428 579.7452 Cancer-related nucleoside-triphosphatase OS=Homo sapiens OX=9606 GN=NTPCR PE=1 SV=1 5.83 1241.9 - 237364 - - - -1.2752 - 1.877 0.409 - 415.9 1 2 0 -0.0015 11 0 0 0 6.06E+08 5.12E+08 - - - 3.7648 0.9984 221125_WJC_METTL3_EV_vs_WT_F09.02915.02915.2 0.00556 14-Nov R.RQC[160.03]EEVAR.A "sp|P51570|GALK1_HUMAN,tr|K7EII7|K7EII7_HUMAN" 2 1046.4927 2.92 124973 2915 2 1046.489377 524.2536 Galactokinase OS=Homo sapiens OX=9606 GN=GALK1 PE=1 SV=1 6.14 1242.3 - 1.20E+06 - - - -3.2012 - 2.267 0.279 - 280.9 1 2 0 -0.0033 8 0 0 0 2.72E+07 9.32E+06 - - - 3.5691 0.9996 221125_WJC_METTL3_EV_vs_WT_F09.02917.02917.2 0.000215 14-Nov R.R[166.11]QC[160.03]EEVAR[166.11].A "sp|P51570|GALK1_HUMAN,tr|K7EII7|K7EII7_HUMAN" 2 1066.5093 2.92 124975 2917 2 1066.509686 534.2619 Galactokinase OS=Homo sapiens OX=9606 GN=GALK1 PE=1 SV=1 6.14 1242.5 - 751256 - - - 0.3929 - 2.144 0.28 - 284.3 1 2 0 0.0004 8 0 0 0 2.72E+07 9.32E+06 - - - 3.4091 1 221125_WJC_METTL3_EV_vs_WT_F09.02919.02919.2 2.33E-09 16-Nov K.NHAC[160.03]EMC[160.03]GK[136.11].A "sp|Q14119|VEZF1_HUMAN,sp|P56270|MAZ_HUMAN,tr|J3QSH4|J3QSH4_HUMAN,tr|I3L2Z5|I3L2Z5_HUMAN,tr|A0A087WWR2|A0A087WWR2_HUMAN" 5 1113.4245 1.17 124977 2919 2 1113.420987 557.7195 Vascular endothelial zinc finger 1 OS=Homo sapiens OX=9606 GN=VEZF1 PE=1 SV=2 6.73 1242.8 - 253274 - - - -3.1722 - 2.451 0.679 - 682.4 1 2 0 -0.0035 9 0 0 0 2.37E+07 2.02E+07 - - - 6.6486 0.9733 221125_WJC_METTL3_EV_vs_WT_F09.02921.02921.2 0.0267 14-Jun R.SKGQESFK.K "sp|P06748|NPM_HUMAN,tr|E5RI98|E5RI98_HUMAN,tr|A0A7I2V5S2|A0A7I2V5S2_HUMAN" 3 909.4556 0.75 124978 2921 2 909.452653 455.7351 Nucleophosmin OS=Homo sapiens OX=9606 GN=NPM1 PE=1 SV=2 8.31 1243 - 2.02E+06 - - - -3.236 - 1.408 0.411 - 83.3 1 2 1 -0.0029 8 0 0 0 2.11E+08 2.82E+08 - - - 3.1077 1 221125_WJC_METTL3_EV_vs_WT_F09.02924.02924.2 5.05E-06 20-Nov R.NADC[160.03]SSGPGQR.V "sp|Q9BSD7|NTPCR_HUMAN,tr|Q5TDF0|Q5TDF0_HUMAN" 2 1147.4676 1.18 124980 2924 2 1147.465428 574.7411 Cancer-related nucleoside-triphosphatase OS=Homo sapiens OX=9606 GN=NTPCR PE=1 SV=1 5.83 1243.3 - 663668 - - - -1.9225 - 2.13 0.655 - 550.6 1 2 0 -0.0022 11 0 0 0 6.06E+08 5.12E+08 - - - 5.9236 0.9986 221125_WJC_METTL3_EV_vs_WT_F09.02929.02929.2 0.00028 20-Jul R.QSSADGSQPPK.K sp|Q15291|RBBP5_HUMAN 1 1100.5098 0.51 124982 2929 2 1100.506446 551.2622 Retinoblastoma-binding protein 5 OS=Homo sapiens OX=9606 GN=RBBP5 PE=1 SV=2 5.84 1244 - 321156 - - - -3.0622 - 1.367 0.495 - 140.9 1 2 0 -0.0034 11 0 0 0 6.14E+06 1.20E+07 - - - 3.5417 0.9904 221125_WJC_METTL3_EV_vs_WT_F09.02930.02930.2 0.102 22-May K.K[136.11]VEGAGEEQAAK[136.11].K sp|P07196|NFL_HUMAN 1 1231.6379 2.35 124983 2930 2 1231.633626 616.8262 Neurofilament light polypeptide OS=Homo sapiens OX=9606 GN=NEFL PE=1 SV=3 4.79 1244.1 - 138303 - - - -3.4953 - 1.149 0.355 - 60.4 1 2 0 -0.0043 12 0 0 0 5.64E+06 2.40E+06 - - - 2.0271 0.9976 221125_WJC_METTL3_EV_vs_WT_F09.02931.02931.2 0.0195 12-Aug K.K[136.11]LEDGPK[136.11].F "sp|P68104|EF1A1_HUMAN,sp|Q5VTE0|EF1A3_HUMAN,tr|A0A7I2V659|A0A7I2V659_HUMAN,tr|A0A7I2V5N4|A0A7I2V5N4_HUMAN,tr|A0A087WVQ9|A0A087WVQ9_HUMAN,tr|A0A087WV01|A0A087WV01_HUMAN" 6 801.4567 0.31 124984 2931 2 801.454574 401.7356 Elongation factor 1-alpha 1 OS=Homo sapiens OX=9606 GN=EEF1A1 PE=1 SV=1 6.07 1244.2 - 587347 - - - -2.6764 - 1.641 0.288 - 219 1 2 0 -0.0021 7 0 0 0 4.91E+06 1.57E+07 - - - 2.7369 0.9974 221125_WJC_METTL3_EV_vs_WT_F09.02932.02932.3 2.52E-07 16/40 R.AGADEDDK[136.11]GPR[166.11].A "sp|P25440|BRD2_HUMAN,tr|H0Y6K2|H0Y6K2_HUMAN,tr|A0A0G2JHL0|A0A0G2JHL0_HUMAN,tr|A0A140T9F7|A0A140T9F7_HUMAN,tr|A0A0G2JK44|A0A0G2JK44_HUMAN,tr|A0A140T9E9|A0A140T9E9_HUMAN,tr|A0A0G2JHN8|A0A0G2JHN8_HUMAN,tr|A0A140T9I1|A0A140T9I1_HUMAN,tr|A0A140T9V2|A0A140T9V2_HUMAN" 9 1147.5224 0.001 124985 2932 3 1147.519845 383.5148 Bromodomain-containing protein 2 OS=Homo sapiens OX=9606 GN=BRD2 PE=1 SV=2 4.23 1244.3 - 599694 - - - -2.2701 - 2.687 0.27 - 439.1 1 2 1 -0.0026 11 0 0 0 0.00E+00 2.09E+07 - - - 4.3575 0.9997 221125_WJC_METTL3_EV_vs_WT_F09.02937.02937.3 3.05E-05 Dec-44 K.K[136.11]VEGAGEEQAAK[136.11].K sp|P07196|NFL_HUMAN 1 1231.6379 2.16 124988 2937 3 1231.633281 411.5533 Neurofilament light polypeptide OS=Homo sapiens OX=9606 GN=NEFL PE=1 SV=3 4.79 1244.9 - 892914 - - - -3.7755 - 2.452 0.464 - 158.9 1 2 0 -0.0046 12 0 0 0 2.08E+07 9.64E+06 - - - 6.1979 0.9984 221125_WJC_METTL3_EV_vs_WT_F09.02946.02946.2 6.92E-07 18-Sep K.DGEEC[160.03]TNEGK.G sp|Q86XN7|PRSR1_HUMAN 1 1137.4244 2.23 124995 2946 2 1137.421211 569.7195 Proline and serine-rich protein 1 OS=Homo sapiens OX=9606 GN=PROSER1 PE=1 SV=2 4 1246 - 497423 - - - -2.8318 - 1.962 0.316 - 407.9 1 2 0 -0.0032 10 0 0 0 3.52E+07 1.58E+07 - - - 3.2552 0.9988 221125_WJC_METTL3_EV_vs_WT_F09.02953.02953.2 0.00263 14-Aug R.DQINSDHR.T sp|Q12874|SF3A3_HUMAN 1 983.4421 3.61 125000 2953 2 983.43884 492.7283 Splicing factor 3A subunit 3 OS=Homo sapiens OX=9606 GN=SF3A3 PE=1 SV=1 5.21 1246.8 - 2.26E+06 - - - -3.2854 - 1.637 0.46 - 378 1 2 0 -0.0032 8 0 0 0 8.15E+07 2.26E+07 - - - 3.924 1 221125_WJC_METTL3_EV_vs_WT_F09.02959.02959.2 4.89E-07 20-Oct R.ETNGNEDEEGR.Q "sp|Q9BUQ8|DDX23_HUMAN,tr|H0YIL9|H0YIL9_HUMAN" 2 1248.4855 10.15 125006 2959 2 1248.480469 625.25 Probable ATP-dependent RNA helicase DDX23 OS=Homo sapiens OX=9606 GN=DDX23 PE=1 SV=3 3.91 1247.6 - 108116 - - - -3.9912 - 2.119 0.711 - 400.2 1 2 0 -0.005 11 0 0 0 1.13E+06 1.11E+05 - - - 6.3224 0.9971 221125_WJC_METTL3_EV_vs_WT_F09.02964.02964.2 0.00892 14-Jul R.DQINSDHR[166.11].T sp|Q12874|SF3A3_HUMAN 1 993.4503 3.6 125009 2964 2 993.447277 497.7324 Splicing factor 3A subunit 3 OS=Homo sapiens OX=9606 GN=SF3A3 PE=1 SV=1 5.21 1248.1 - 1.86E+06 - - - -3.0842 - 1.477 0.351 - 289.3 1 2 0 -0.0031 8 0 0 0 8.13E+07 2.26E+07 - - - 2.8088 1 221125_WJC_METTL3_EV_vs_WT_F09.02966.02966.2 3.37E-07 16-Oct K.NHAC[160.03]EMC[160.03]GK.A "sp|Q14119|VEZF1_HUMAN,sp|P56270|MAZ_HUMAN,tr|J3QSH4|J3QSH4_HUMAN,tr|I3L2Z5|I3L2Z5_HUMAN,tr|A0A087WWR2|A0A087WWR2_HUMAN" 5 1105.4103 1.17 125011 2966 2 1105.407151 553.7124 Vascular endothelial zinc finger 1 OS=Homo sapiens OX=9606 GN=VEZF1 PE=1 SV=2 6.73 1248.2 - 1.08E+06 - - - -2.8659 - 2.238 0.647 - 554.7 1 2 0 -0.0032 9 0 0 0 2.37E+07 2.02E+07 - - - 6.1493 0.966 221125_WJC_METTL3_EV_vs_WT_F09.02967.02967.2 0.021 14-Sep R.SK[136.11]NDSK[136.11]PY.- "sp|Q92879|CELF1_HUMAN,sp|O95319|CELF2_HUMAN,tr|G5EA30|G5EA30_HUMAN,tr|E9PC62|E9PC62_HUMAN,tr|A0A1B0GU44|A0A1B0GU44_HUMAN,tr|A0A0J9YX66|A0A0J9YX66_HUMAN,tr|A0A1B0GUN8|A0A1B0GUN8_HUMAN,tr|Q5VZZ6|Q5VZZ6_HUMAN,tr|A0A0J9YXJ0|A0A0J9YXJ0_HUMAN,tr|V9GYD9|V9GYD9_HUMAN" 10 953.4789 1.22 125012 2967 2 953.475496 477.7467 CUGBP Elav-like family member 1 OS=Homo sapiens OX=9606 GN=CELF1 PE=1 SV=2 8.22 1248.4 - 776220 - - - -3.5816 - 1.678 0.34 - 199.7 1 2 1 -0.0034 8 0 0 0 2.14E+07 1.76E+07 - - - 3.1122 0.9982 221125_WJC_METTL3_EV_vs_WT_F09.02968.02968.2 1.40E-05 18-Nov R.HAESVGDGER.V sp|P30533|AMRP_HUMAN 1 1055.4632 0 125013 2968 2 1055.458011 528.7389 Alpha-2-macroglobulin receptor-associated protein OS=Homo sapiens OX=9606 GN=LRPAP1 PE=1 SV=1 4.65 1248.5 - 508871 - - - -4.9173 - 2.052 0.565 - 344.4 1 2 0 -0.0052 10 0 0 0 2.39E+06 5.25E+08 - - - 5.2189 0.9974 221125_WJC_METTL3_EV_vs_WT_F09.02975.02975.2 0.014 20-Jun K.GSATPSGQESR[166.11].T sp|Q14781|CBX2_HUMAN 1 1085.4977 8.54 125020 2975 2 1085.501272 543.7561 Chromobox protein homolog 2 OS=Homo sapiens OX=9606 GN=CBX2 PE=1 SV=2 6 1249.4 - 183822 - - - 3.3045 - 1.671 0.366 - 117.9 1 2 0 0.0036 11 0 0 0 8.84E+07 1.04E+07 - - - 3.1321 0.9869 221125_WJC_METTL3_EV_vs_WT_F09.02981.02981.2 0.00783 14-Oct R.SKNDSKPY.- "sp|Q92879|CELF1_HUMAN,sp|O95319|CELF2_HUMAN,tr|G5EA30|G5EA30_HUMAN,tr|E9PC62|E9PC62_HUMAN,tr|A0A1B0GU44|A0A1B0GU44_HUMAN,tr|A0A0J9YX66|A0A0J9YX66_HUMAN,tr|A0A1B0GUN8|A0A1B0GUN8_HUMAN,tr|Q5VZZ6|Q5VZZ6_HUMAN,tr|A0A0J9YXJ0|A0A0J9YXJ0_HUMAN,tr|V9GYD9|V9GYD9_HUMAN" 10 937.4505 1.22 125023 2981 2 937.447477 469.7325 CUGBP Elav-like family member 1 OS=Homo sapiens OX=9606 GN=CELF1 PE=1 SV=2 8.22 1250.1 - 2.19E+06 - - - -3.2364 - 1.739 0.438 - 227 1 2 1 -0.003 8 0 0 0 2.14E+07 1.75E+07 - - - 3.9439 0.9707 221125_WJC_METTL3_EV_vs_WT_F09.02982.02982.2 0.000976 16-Nov K.SSENK[136.11]LETK[136.11].V "sp|Q6KC79|NIPBL_HUMAN,tr|A0A590UJS4|A0A590UJS4_HUMAN" 2 1050.5528 2.95 125024 2982 2 1050.550267 526.2837 Nipped-B-like protein OS=Homo sapiens OX=9606 GN=NIPBL PE=1 SV=2 5.86 1250.2 - 1.04E+06 - - - -2.4149 - 2.092 0.171 - 554.7 1 2 1 -0.0025 9 0 0 0 3.00E+07 1.02E+07 - - - 2.4386 0.9875 221125_WJC_METTL3_EV_vs_WT_F09.02988.02988.2 0.000681 16-Dec K.SSENKLETK.V "sp|Q6KC79|NIPBL_HUMAN,tr|A0A590UJS4|A0A590UJS4_HUMAN" 2 1034.5244 3.05 125028 2988 2 1034.521296 518.2695 Nipped-B-like protein OS=Homo sapiens OX=9606 GN=NIPBL PE=1 SV=2 5.86 1251 - 1.75E+06 - - - -3.0043 - 2.288 0.318 - 688 1 2 1 -0.0031 9 0 0 0 3.10E+07 1.02E+07 - - - 3.7833 0.9947 221125_WJC_METTL3_EV_vs_WT_F09.02990.02990.2 0.0195 14-Aug R.K[136.11]LTPQGQR[166.11].D "sp|P39019|RS19_HUMAN,tr|A0A075B6E2|A0A075B6E2_HUMAN" 2 944.5522 1.14 125030 2990 2 944.549188 473.2834 40S ribosomal protein S19 OS=Homo sapiens OX=9606 GN=RPS19 PE=1 SV=2 11 1251.2 - 1.06E+06 - - - -3.2248 - 1.979 0.171 - 263.3 1 2 0 -0.003 8 0 0 0 3.37E+07 2.95E+07 - - - 2.3617 0.9986 221125_WJC_METTL3_EV_vs_WT_F09.02992.02992.2 0.000323 16-Nov K.KSTLNPNAK.E "sp|Q8WWM7|ATX2L_HUMAN,sp|Q99700|ATX2_HUMAN,tr|F8W0B5|F8W0B5_HUMAN,tr|A0A5F9ZHW5|A0A5F9ZHW5_HUMAN,tr|A0A5F9ZHH4|A0A5F9ZHH4_HUMAN,tr|F8WB05|F8WB05_HUMAN,tr|A0A5F9ZI57|A0A5F9ZI57_HUMAN,tr|A0A2R8YDM9|A0A2R8YDM9_HUMAN,tr|H3BUF6|H3BUF6_HUMAN,tr|F8VQP2|F8VQP2_HUMAN,tr|A0A2R8Y5A6|A0A2R8Y5A6_HUMAN,tr|S4R3J6|S4R3J6_HUMAN,tr|F8WB06|F8WB06_HUMAN,tr|V9GY86|V9GY86_HUMAN,tr|A0A2R8Y7E6|A0A2R8Y7E6_HUMAN,tr|A0A5F9ZHX3|A0A5F9ZHX3_HUMAN,tr|H0YH87|H0YH87_HUMAN,tr|A0A2R8Y7P6|A0A2R8Y7P6_HUMAN" 18 971.54 2.06 125031 2992 2 971.537191 486.7773 Ataxin-2-like protein OS=Homo sapiens OX=9606 GN=ATXN2L PE=1 SV=2 10 1251.5 - 792063 - - - -2.8851 - 1.915 0.344 - 368.1 1 2 0 -0.0028 9 0 0 0 1.44E+07 7.00E+06 - - - 3.4606 0.9759 221125_WJC_METTL3_EV_vs_WT_F09.02997.02997.2 0.00986 18-Oct K.AKDSIDAGSK.E "sp|Q96C01|F136A_HUMAN,tr|E7EQY1|E7EQY1_HUMAN" 2 990.4982 1.61 125034 2997 2 990.494776 496.2564 Protein FAM136A OS=Homo sapiens OX=9606 GN=FAM136A PE=1 SV=1 6 1252.1 - 1.21E+06 - - - -3.4457 - 2.095 0.309 - 212.4 1 2 1 -0.0034 10 0 0 0 1.08E+07 6.71E+06 - - - 3.3865 0.9968 221125_WJC_METTL3_EV_vs_WT_F09.02999.02999.3 0.0132 Aug-32 K.QTHSQELC[160.03]K[136.11].L "sp|P52732|KIF11_HUMAN,tr|A0A7I2V3A9|A0A7I2V3A9_HUMAN" 2 1137.5328 0.001 125036 2999 3 1137.52964 380.1849 Kinesin-like protein KIF11 OS=Homo sapiens OX=9606 GN=KIF11 PE=1 SV=2 6.74 1252.3 - 1.65E+06 - - - -2.7841 - 1.699 0.285 - 108.7 1 2 0 -0.0032 9 0 0 0 0.00E+00 2.91E+07 - - - 3.314 0.9964 221125_WJC_METTL3_EV_vs_WT_F09.03006.03006.2 2.97E-06 18-Oct R.SPTDC[160.03]AQSSK.S sp|O00443|P3C2A_HUMAN 1 1079.4553 1.33 125042 3006 2 1079.448827 540.7349 Phosphatidylinositol 4-phosphate 3-kinase C2 domain-containing subunit alpha OS=Homo sapiens OX=9606 GN=PIK3C2A PE=1 SV=2 5.55 1253.1 - 386395 - - - -6.0317 - 1.915 0.619 - 456.3 1 2 0 -0.0065 10 0 0 0 3.91E+07 2.94E+07 - - - 5.4244 0.9958 221125_WJC_METTL3_EV_vs_WT_F09.03014.03014.2 0.107 14-Aug R.KLTPQGQR.D "sp|P39019|RS19_HUMAN,tr|A0A075B6E2|A0A075B6E2_HUMAN" 2 926.5298 1.14 125048 3014 2 926.527287 464.2722 40S ribosomal protein S19 OS=Homo sapiens OX=9606 GN=RPS19 PE=1 SV=2 11 1253.9 - 3.73E+06 - - - -2.6734 - 1.871 0.173 - 276 1 2 0 -0.0025 8 0 0 0 3.38E+07 2.96E+07 - - - 2.2074 0.9966 221125_WJC_METTL3_EV_vs_WT_F09.03017.03017.3 0.000147 13/40 K.TKQGVTEAAEK.T "sp|O76070|SYUG_HUMAN,sp|Q16143|SYUB_HUMAN,tr|F8W754|F8W754_HUMAN,tr|G4Y816|G4Y816_HUMAN" 4 1160.6037 1.33 125051 3017 3 1160.600355 387.8752 Gamma-synuclein OS=Homo sapiens OX=9606 GN=SNCG PE=1 SV=2 5.81 1254.3 - 476882 - - - -2.8968 - 2.265 0.327 - 285.1 1 2 1 -0.0034 11 0 0 0 1.69E+07 1.28E+07 - - - 4.5074 1 221125_WJC_METTL3_EV_vs_WT_F09.03018.03018.2 2.25E-10 17/26 R.PSQAAGDNQGDEAK.E "sp|Q9Y2W1|TR150_HUMAN,tr|A0A3B3ITZ9|A0A3B3ITZ9_HUMAN" 2 1386.6012 2.93 125052 3018 2 1386.599454 694.3079 Thyroid hormone receptor-associated protein 3 OS=Homo sapiens OX=9606 GN=THRAP3 PE=1 SV=2 4.03 1254.4 - 467291 - - - -1.2239 - 3.538 0.691 - 1339.8 1 1 0 -0.0017 14 0 0 0 2.67E+08 9.10E+07 - - - 7.315 0.9874 221125_WJC_METTL3_EV_vs_WT_F09.03019.03019.2 0.000392 14-Sep Q.THSQELC[160.03]K.L "sp|P52732|KIF11_HUMAN,tr|A0A7I2V3A9|A0A7I2V3A9_HUMAN" 2 1001.46 10.81 125053 3019 2 1001.459749 501.7373 Kinesin-like protein KIF11 OS=Homo sapiens OX=9606 GN=KIF11 PE=1 SV=2 6.41 1254.6 - 308465 - - - -0.2806 - 1.733 0.446 - 409.4 1 1 0 -0.0003 8 0 0 0 3.11E+06 2.88E+05 - - - 3.9934 1 221125_WJC_METTL3_EV_vs_WT_F09.03020.03020.2 3.30E-12 17/26 R.PSQAAGDNQGDEAK[136.11].E "sp|Q9Y2W1|TR150_HUMAN,tr|A0A3B3ITZ9|A0A3B3ITZ9_HUMAN" 2 1394.6154 2.93 125054 3020 2 1394.612266 698.315 Thyroid hormone receptor-associated protein 3 OS=Homo sapiens OX=9606 GN=THRAP3 PE=1 SV=2 4.03 1254.7 - 284046 - - - -2.2121 - 3.439 0.73 - 856.8 1 1 0 -0.0031 14 0 0 0 2.67E+08 9.10E+07 - - - 7.5314 0.9996 221125_WJC_METTL3_EV_vs_WT_F09.03025.03025.2 1.28E-07 18-Dec R.SPTDC[160.03]AQSSK[136.11].S sp|O00443|P3C2A_HUMAN 1 1087.4695 1.33 125057 3025 2 1087.466306 544.742 Phosphatidylinositol 4-phosphate 3-kinase C2 domain-containing subunit alpha OS=Homo sapiens OX=9606 GN=PIK3C2A PE=1 SV=2 5.55 1255.2 - 2.02E+06 - - - -2.972 - 2.315 0.539 - 606.7 1 2 0 -0.0032 10 0 0 0 3.91E+07 2.94E+07 - - - 5.3641 0.9717 221125_WJC_METTL3_EV_vs_WT_F09.03028.03028.2 0.0836 18-Jun R.SAVPPGADK[136.11]K[136.11].A "sp|P46783|RS10_HUMAN,tr|F6U211|F6U211_HUMAN,tr|A0A1W2PQS6|A0A1W2PQS6_HUMAN,tr|A0A2R8YFH6|A0A2R8YFH6_HUMAN,tr|A0A2R8Y7H1|A0A2R8Y7H1_HUMAN,tr|S4R435|S4R435_HUMAN" 6 984.5575 1.33 125060 3028 2 984.552803 493.286 40S ribosomal protein S10 OS=Homo sapiens OX=9606 GN=RPS10 PE=1 SV=1 8.31 1255.6 - 633462 - - - -4.7656 - 1.359 0.269 - 150.4 1 2 0 -0.0047 10 0 0 0 9.54E+06 7.15E+06 - - - 1.8826 0.9937 221125_WJC_METTL3_EV_vs_WT_F09.03029.03029.2 0.00054 20-Dec K.TK[136.11]QGVTEAAEK[136.11].T "sp|O76070|SYUG_HUMAN,sp|Q16143|SYUB_HUMAN,tr|F8W754|F8W754_HUMAN,tr|G4Y816|G4Y816_HUMAN" 4 1176.6321 1.58 125061 3029 2 1176.628558 589.3233 Gamma-synuclein OS=Homo sapiens OX=9606 GN=SNCG PE=1 SV=2 5.81 1255.7 - 409039 - - - -3.0247 - 2.303 0.477 - 351.9 1 2 1 -0.0036 11 0 0 0 5.28E+06 3.35E+06 - - - 4.8197 0.9992 221125_WJC_METTL3_EV_vs_WT_F09.03035.03035.2 1.60E-06 18-Nov R.QQAQEENEAR.E sp|Q96SC8|DMTA2_HUMAN 1 1201.5323 1.79 125065 3035 2 1201.528973 601.7734 Doublesex- and mab-3-related transcription factor A2 OS=Homo sapiens OX=9606 GN=DMRTA2 PE=2 SV=2 4.25 1256.5 - 841577 - - - -2.8048 - 2.273 0.376 - 713.2 1 2 0 -0.0034 10 0 0 0 5.03E+06 2.81E+06 - - - 4.109 0.9993 221125_WJC_METTL3_EV_vs_WT_F09.03039.03039.2 0.148 18-Nov R.QQAQEENEAR[166.11].E sp|Q96SC8|DMTA2_HUMAN 1 1211.5406 1.79 125069 3039 2 1211.537138 606.7776 Doublesex- and mab-3-related transcription factor A2 OS=Homo sapiens OX=9606 GN=DMRTA2 PE=2 SV=2 4.25 1257.1 - 507069 - - - -2.8682 - 2.173 0.427 - 695.7 1 2 0 -0.0035 10 0 0 0 5.03E+06 2.81E+06 - - - 4.3601 0.9905 221125_WJC_METTL3_EV_vs_WT_F09.03049.03049.3 0.000355 13/52 R.PSQAAGDNQGDEAK.E "sp|Q9Y2W1|TR150_HUMAN,tr|A0A3B3ITZ9|A0A3B3ITZ9_HUMAN" 2 1386.6012 3.42 125077 3049 3 1386.597401 463.2077 Thyroid hormone receptor-associated protein 3 OS=Homo sapiens OX=9606 GN=THRAP3 PE=1 SV=2 4.03 1258.3 - 1.22E+06 - - - -2.7045 - 2.129 0.534 - 227.4 1 1 0 -0.0037 14 0 0 0 7.15E+06 2.09E+06 - - - 6.5007 0.9932 221125_WJC_METTL3_EV_vs_WT_F09.03056.03056.3 0.00156 Nov-40 K.TK[136.11]QGVTEAAEK[136.11].T "sp|O76070|SYUG_HUMAN,sp|Q16143|SYUB_HUMAN,tr|F8W754|F8W754_HUMAN,tr|G4Y816|G4Y816_HUMAN" 4 1176.6321 1.33 125082 3056 3 1176.628229 393.218 Gamma-synuclein OS=Homo sapiens OX=9606 GN=SNCG PE=1 SV=2 5.81 1259.2 - 606491 - - - -3.3043 - 2.026 0.326 - 196.3 1 2 1 -0.0039 11 0 0 0 1.69E+07 1.28E+07 - - - 4.1793 0.9994 221125_WJC_METTL3_EV_vs_WT_F09.03065.03065.2 0.0697 13/14 K.K[136.11]DENEIEK[136.11].L "sp|Q14683|SMC1A_HUMAN,tr|G8JLG1|G8JLG1_HUMAN,tr|A0A6Q8PHC3|A0A6Q8PHC3_HUMAN" 3 1019.5106 1.07 125089 3065 2 1019.508021 510.7626 Structural maintenance of chromosomes protein 1A OS=Homo sapiens OX=9606 GN=SMC1A PE=1 SV=2 4.41 1260.3 - 673064 - - - -2.5345 - 2.414 0.339 - 523.1 1 2 0 -0.0026 8 0 0 0 6.18E+07 5.79E+07 - - - 4.202 0.9834 221125_WJC_METTL3_EV_vs_WT_F09.03073.03073.2 0.42 12-Jul K.DEDYK[136.11]QR[166.11].T "sp|Q00839|HNRPU_HUMAN,tr|A0A1W2PQL0|A0A1W2PQL0_HUMAN,tr|A0A1W2PPL4|A0A1W2PPL4_HUMAN,tr|A0A1W2PQ74|A0A1W2PQ74_HUMAN,tr|Q5RI18|Q5RI18_HUMAN,tr|A0A1W2PP35|A0A1W2PP35_HUMAN,tr|A0A1W2PPS1|A0A1W2PPS1_HUMAN,tr|A0A1W2PRZ7|A0A1W2PRZ7_HUMAN,tr|A0A1W2PPH7|A0A1W2PPH7_HUMAN,tr|A0A1W2PQD4|A0A1W2PQD4_HUMAN,tr|A0A1W2PP34|A0A1W2PP34_HUMAN,tr|A0A1X7SBS1|A0A1X7SBS1_HUMAN" 12 970.4475 0.96 125095 3073 2 970.445405 486.231 Heterogeneous nuclear ribonucleoprotein U OS=Homo sapiens OX=9606 GN=HNRNPU PE=1 SV=6 4.56 1261.4 - 2.12E+06 - - - -2.1526 - 1.573 0.315 - 392.3 1 2 1 -0.0021 7 0 0 0 4.24E+08 4.42E+08 - - - 2.8022 0.9974 221125_WJC_METTL3_EV_vs_WT_F09.03077.03077.2 0.63 12-Jul R.KQHSLLK.R "sp|P62841|RS15_HUMAN,tr|K7EJ78|K7EJ78_HUMAN,tr|K7EM56|K7EM56_HUMAN,tr|A0A0B4J2B4|A0A0B4J2B4_HUMAN,tr|S4R456|S4R456_HUMAN,tr|K7ELC2|K7ELC2_HUMAN,tr|K7EQJ5|K7EQJ5_HUMAN,tr|S4R417|S4R417_HUMAN" 8 852.5181 1.27 125099 3077 2 852.516658 427.2663 40S ribosomal protein S15 OS=Homo sapiens OX=9606 GN=RPS15 PE=1 SV=2 10 1261.8 - 697194 - - - -1.7349 - 1.678 0.185 - 199.8 1 2 0 -0.0015 7 0 0 0 1.87E+07 1.47E+07 - - - 2.047 0.9998 221125_WJC_METTL3_EV_vs_WT_F09.03086.03086.2 7.48E-05 22-Aug K.TAESSGGPSTSR[166.11].V "sp|P19447|ERCC3_HUMAN,tr|A0A2R8Y762|A0A2R8Y762_HUMAN,tr|H7C309|H7C309_HUMAN,tr|A0A2R8Y5L2|A0A2R8Y5L2_HUMAN,tr|A0A2R8Y6W8|A0A2R8Y6W8_HUMAN,tr|A0A2R8YES7|A0A2R8YES7_HUMAN" 6 1145.5188 0.32 125108 3086 2 1145.518463 573.7667 General transcription and DNA repair factor IIH helicase subunit XPB OS=Homo sapiens OX=9606 GN=ERCC3 PE=1 SV=1 5.66 1263 - 110420 - - - -0.3073 - 1.773 0.52 - 214.3 1 2 0 -0.0004 12 0 0 0 1.78E+06 5.57E+06 - - - 4.3884 0.8231 221125_WJC_METTL3_EV_vs_WT_F09.03096.03096.2 0.0997 18-Jun Q.SVGGDSSADR[166.11].L "sp|Q86U44|MTA70_HUMAN,tr|H0YFV6|H0YFV6_HUMAN" 2 959.4184 0.16 125116 3096 2 959.416809 480.7165 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 4.21 1263.9 - 793985 - - - -1.6291 - 1.121 0.323 - 71.2 1 1 0 -0.0016 10 0 0 0 1.99E+06 1.27E+07 - - - 1.745 0.9271 221125_WJC_METTL3_EV_vs_WT_F09.03099.03099.2 0.674 20-Jul R.RGAAASPEPAR.A sp|P84157|MXRA7_HUMAN 1 1081.5629 1.59 125119 3099 2 1081.560315 541.7887 Matrix-remodeling-associated protein 7 OS=Homo sapiens OX=9606 GN=MXRA7 PE=1 SV=1 9.6 1264.3 - 279269 - - - -2.3485 - 1.175 0.064 - 60 1 2 0 -0.0025 11 0 0 0 4.61E+06 2.90E+06 - - - -0.0508 0.9985 221125_WJC_METTL3_EV_vs_WT_F09.03103.03103.2 0.0551 16-Sep K.YTTTSSSSR.K "sp|P48668|K2C6C_HUMAN,sp|P04259|K2C6B_HUMAN,sp|P02538|K2C6A_HUMAN" 3 988.4462 75.41 125121 3103 2 988.442317 495.2304 "Keratin, type II cytoskeletal 6C OS=Homo sapiens OX=9606 GN=KRT6C PE=1 SV=3" 8.75 1264.7 - 2.76E+06 - - - -3.8819 - 1.846 0.464 - 287.4 1 2 0 -0.0038 9 0 0 0 6.19E+07 8.21E+05 - - - 4.2404 0.8405 221125_WJC_METTL3_EV_vs_WT_F09.03108.03108.3 0.132 Nov-40 K.EK[136.11]DGTTDSGIK[136.11].L sp|Q9NW64|RBM22_HUMAN 1 1165.5797 0.78 125124 3108 3 1165.575525 389.5339 Pre-mRNA-splicing factor RBM22 OS=Homo sapiens OX=9606 GN=RBM22 PE=1 SV=1 4.56 1265.5 - 1.90E+06 - - - -3.6222 - 1.846 0.157 - 188.4 1 2 1 -0.0042 11 0 0 0 1.48E+07 1.90E+07 - - - 2.0307 0.9859 221125_WJC_METTL3_EV_vs_WT_F09.03112.03112.2 0.000956 20-Jul R.VGEGDK[136.11]EDATR[166.11].R sp|Q8WXX5|DNJC9_HUMAN 1 1193.5643 1.36 125128 3112 2 1193.560821 597.7894 DnaJ homolog subfamily C member 9 OS=Homo sapiens OX=9606 GN=DNAJC9 PE=1 SV=1 4.32 1266 - 192501 - - - -2.9274 - 1.35 0.504 - 152.3 1 2 1 -0.0035 11 0 0 0 2.23E+06 1.64E+06 - - - 3.5743 0.9896 221125_WJC_METTL3_EV_vs_WT_F09.03117.03117.2 0.000501 20-Nov K.EK[136.11]DGTTDSGIK[136.11].L sp|Q9NW64|RBM22_HUMAN 1 1165.5797 0.77 125131 3117 2 1165.57636 583.7971 Pre-mRNA-splicing factor RBM22 OS=Homo sapiens OX=9606 GN=RBM22 PE=1 SV=1 4.56 1266.6 - 563122 - - - -2.9059 - 1.788 0.45 - 291.7 1 2 1 -0.0034 11 0 0 0 3.57E+06 4.63E+06 - - - 3.9356 0.9623 221125_WJC_METTL3_EV_vs_WT_F09.03121.03121.2 0.00648 20-Sep K.EKDGTTDSGIK.L sp|Q9NW64|RBM22_HUMAN 1 1149.5513 0.77 125135 3121 2 1149.547716 575.7829 Pre-mRNA-splicing factor RBM22 OS=Homo sapiens OX=9606 GN=RBM22 PE=1 SV=1 4.56 1267 - 407649 - - - -3.1586 - 1.582 0.328 - 146.2 1 2 1 -0.0036 11 0 0 0 3.57E+06 4.63E+06 - - - 2.7033 0.9977 221125_WJC_METTL3_EV_vs_WT_F09.03122.03122.2 0.00297 20-Jun K.EVNNESGESQR[166.11].G sp|Q9NQS1|AVEN_HUMAN 1 1257.5461 1.44 125136 3122 2 1257.541835 629.7803 Cell death regulator Aven OS=Homo sapiens OX=9606 GN=AVEN PE=1 SV=1 4.25 1267.1 - 281693 - - - -3.3852 - 1.453 0.438 - 130.9 1 2 0 -0.0043 11 0 0 0 3.16E+06 2.20E+06 - - - 3.2855 0.9995 221125_WJC_METTL3_EV_vs_WT_F09.03127.03127.2 0.000163 16-Oct R.QHLEETTQK.A sp|P12270|TPR_HUMAN 1 1112.5462 2.72 125139 3127 2 1112.543978 557.2804 Nucleoprotein TPR OS=Homo sapiens OX=9606 GN=TPR PE=1 SV=3 5.4 1267.7 - 2.61E+06 - - - -1.999 - 1.694 0.441 - 369.9 1 2 0 -0.0022 9 0 0 0 2.38E+07 8.73E+06 - - - 3.8224 0.8953 221125_WJC_METTL3_EV_vs_WT_F09.03128.03128.2 0.628 14-Aug L.RNDEELNK.L "sp|P16104|H2AX_HUMAN,sp|Q9BTM1|H2AJ_HUMAN,sp|Q93077|H2A1C_HUMAN,sp|Q99878|H2A1J_HUMAN,sp|Q16777|H2A2C_HUMAN,sp|Q8IUE6|H2A2B_HUMAN,sp|Q96QV6|H2A1A_HUMAN,sp|P04908|H2A1B_HUMAN,sp|P20671|H2A1D_HUMAN,sp|P0C0S8|H2A1_HUMAN,sp|Q6FI13|H2A2A_HUMAN,sp|Q96KK5|H2A1H_HUMAN,sp|Q7L7L0|H2A3_HUMAN,tr|A0A0U1RR32|A0A0U1RR32_HUMAN,tr|A0A0U1RRH7|A0A0U1RRH7_HUMAN,tr|A0A3B3IS11|A0A3B3IS11_HUMAN,tr|H0YFX9|H0YFX9_HUMAN" 17 1016.4887 13.85 125140 3128 2 1016.48636 509.2516 Histone H2AX OS=Homo sapiens OX=9606 GN=H2AX PE=1 SV=2 4.68 1267.8 - 1.59E+06 - - - -2.2893 - 1.693 0.274 - 276.2 1 1 0 -0.0023 8 0 0 0 2.75E+07 1.98E+06 - - - 2.6519 0.8353 221125_WJC_METTL3_EV_vs_WT_F09.03129.03129.3 0.268 Aug-40 K.EKDGTTDSGIK.L sp|Q9NW64|RBM22_HUMAN 1 1149.5513 0.79 125141 3129 3 1149.549148 384.1911 Pre-mRNA-splicing factor RBM22 OS=Homo sapiens OX=9606 GN=RBM22 PE=1 SV=1 4.56 1267.8 - 1.50E+06 - - - -1.9129 - 1.369 0.165 - 76.7 1 2 1 -0.0022 11 0 0 0 1.50E+07 1.90E+07 - - - 1.2712 0.9998 221125_WJC_METTL3_EV_vs_WT_F09.03130.03130.2 1.57E-05 16-Oct R.QHLEETTQK[136.11].A sp|P12270|TPR_HUMAN 1 1120.5604 2.72 125142 3130 2 1120.562044 561.2875 Nucleoprotein TPR OS=Homo sapiens OX=9606 GN=TPR PE=1 SV=3 5.4 1267.9 - 1.01E+06 - - - 1.4653 - 1.774 0.527 - 343.9 1 2 0 0.0016 9 0 0 0 2.38E+07 8.73E+06 - - - 4.5913 0.9998 221125_WJC_METTL3_EV_vs_WT_F09.03131.03131.2 0.00045 13/18 R.KGAAPAPPGK.T "sp|Q13428|TCOF_HUMAN,tr|E7ETY2|E7ETY2_HUMAN,tr|H0Y8Y7|H0Y8Y7_HUMAN,tr|A0A3B3IS06|A0A3B3IS06_HUMAN,tr|A0A6I8PRA0|A0A6I8PRA0_HUMAN,tr|A0A2R8Y857|A0A2R8Y857_HUMAN" 6 892.5131 1.21 125143 3131 2 892.511353 447.2638 Treacle protein OS=Homo sapiens OX=9606 GN=TCOF1 PE=1 SV=3 10 1268 - 689662 - - - -1.9025 - 2.427 0.448 - 624.4 1 2 0 -0.0017 10 0 0 0 2.25E+07 1.85E+07 - - - 4.8243 1 221125_WJC_METTL3_EV_vs_WT_F09.03133.03133.2 2.13E-06 16/18 R.K[136.11]GAAPAPPGK[136.11].T "sp|Q13428|TCOF_HUMAN,tr|E7ETY2|E7ETY2_HUMAN,tr|H0Y8Y7|H0Y8Y7_HUMAN,tr|A0A3B3IS06|A0A3B3IS06_HUMAN,tr|A0A6I8PRA0|A0A6I8PRA0_HUMAN,tr|A0A2R8Y857|A0A2R8Y857_HUMAN" 6 908.5415 1.21 125145 3133 2 908.539523 455.278 Treacle protein OS=Homo sapiens OX=9606 GN=TCOF1 PE=1 SV=3 10 1268.3 - 507494 - - - -2.1221 - 3.022 0.578 - 963.3 1 2 0 -0.0019 10 0 0 0 2.25E+07 1.85E+07 - - - 6.3965 0.8587 221125_WJC_METTL3_EV_vs_WT_F09.03139.03139.3 0.138 Sep-32 R.QQITEK[136.11]EEK[136.11].T sp|P12270|TPR_HUMAN 1 1147.6056 0.001 125149 3139 3 1147.604958 383.5425 Nucleoprotein TPR OS=Homo sapiens OX=9606 GN=TPR PE=1 SV=3 4.79 1268.9 - 1.19E+06 - - - -0.5315 - 1.698 0.084 - 139.5 1 2 1 -0.0006 9 0 0 0 0.00E+00 8.63E+06 - - - 1.072 0.9918 221125_WJC_METTL3_EV_vs_WT_F09.03140.03140.2 2.91E-05 20-Nov S.SSSGYGGGSSR.V sp|P35527|K1C9_HUMAN 1 1000.421 18.73 125150 3140 2 1000.419588 501.2178 "Keratin, type I cytoskeletal 9 OS=Homo sapiens OX=9606 GN=KRT9 PE=1 SV=3" 8.46 1269 - 1.64E+06 - - - -1.4124 - 2.127 0.58 - 400.7 1 1 0 -0.0014 11 0 0 0 2.56E+07 1.37E+06 - - - 5.3661 0.9997 221125_WJC_METTL3_EV_vs_WT_F09.03142.03142.3 0.025 Nov-36 K.TEADNAER[166.11]PR[166.11].A sp|P52952|NKX25_HUMAN 1 1177.5591 1.18 125152 3142 3 1177.556792 393.527 Homeobox protein Nkx-2.5 OS=Homo sapiens OX=9606 GN=NKX2-5 PE=1 SV=1 4.68 1269.3 - 453194 - - - -1.9209 - 1.955 0.388 - 281.4 1 2 0 -0.0023 10 0 0 0 1.06E+07 8.94E+06 - - - 4.823 0.9305 221125_WJC_METTL3_EV_vs_WT_F09.03144.03144.2 1.55E-06 26-Sep G.GGSYGSGGGGGGGR.G sp|P04264|K2C1_HUMAN 1 1081.4537 5.6 125154 3144 2 1081.450996 541.7341 "Keratin, type II cytoskeletal 1 OS=Homo sapiens OX=9606 GN=KRT1 PE=1 SV=6" 8.75 1269.5 - 310734 - - - -2.4994 - 1.704 0.389 - 221.9 1 1 0 -0.0027 14 0 0 0 2.46E+06 4.39E+05 - - - 3.2508 1 221125_WJC_METTL3_EV_vs_WT_F09.03146.03146.2 0.000134 18-Nov K.HLEQQEGQPK.H sp|P07476|INVO_HUMAN 1 1192.5837 94.13 125156 3146 2 1192.583256 597.2991 Involucrin OS=Homo sapiens OX=9606 GN=IVL PE=1 SV=2 5.4 1269.8 - 147025 - - - -0.3304 - 2.315 0.597 - 406 1 2 0 -0.0004 10 0 0 0 5.09E+06 5.41E+04 - - - 5.7934 0.9998 221125_WJC_METTL3_EV_vs_WT_F09.03150.03150.2 0.000188 20-Dec K.SEEEQSSSSVK.K "sp|P07910|HNRPC_HUMAN,tr|B4DY08|B4DY08_HUMAN,tr|G3V5V7|G3V5V7_HUMAN,tr|B2R5W2|B2R5W2_HUMAN,tr|G3V4C1|G3V4C1_HUMAN,tr|G3V2D6|G3V2D6_HUMAN,tr|G3V4W0|G3V4W0_HUMAN,tr|G3V2Q1|G3V2Q1_HUMAN" 8 1195.5204 1.57 125158 3150 2 1195.518359 598.7675 Heterogeneous nuclear ribonucleoproteins C1\C2 OS=Homo sapiens OX=9606 GN=HNRNPC PE=1 SV=4 4.25 1270.3 - 1.77E+06 - - - -1.7415 - 2.488 0.549 - 559.5 1 2 0 -0.0021 11 0 0 0 3.33E+08 2.12E+08 - - - 5.561 0.9938 221125_WJC_METTL3_EV_vs_WT_F09.03151.03151.2 0.157 16-Jun R.GSEPVPEKK.L "sp|Q8WU79|SMAP2_HUMAN,tr|A0A087WV97|A0A087WV97_HUMAN,tr|X6RCC3|X6RCC3_HUMAN" 3 969.5131 0.9 125159 3151 2 969.511508 485.7638 Stromal membrane-associated protein 2 OS=Homo sapiens OX=9606 GN=SMAP2 PE=1 SV=1 6.14 1270.4 - 998006 - - - -1.6534 - 1.193 0.242 - 159.2 1 2 0 -0.0016 9 0 0 0 6.80E+06 7.55E+06 - - - 1.3384 0.9088 221125_WJC_METTL3_EV_vs_WT_F09.03152.03152.2 0.0197 14-Jul H.DVLHSDKK.L sp|Q00535|CDK5_HUMAN 1 940.4978 3.65 125160 3152 2 940.496317 471.2562 Cyclin-dependent-like kinase 5 OS=Homo sapiens OX=9606 GN=CDK5 PE=1 SV=3 6.75 1270.5 - 860736 - - - -1.5715 - 1.404 0.309 - 219 1 1 0 -0.0015 8 0 0 0 6.94E+06 1.90E+06 - - - 2.3462 0.9996 221125_WJC_METTL3_EV_vs_WT_F09.03155.03155.2 0.000263 18-Sep R.EQQPSSASER.Q sp|P12270|TPR_HUMAN 1 1117.5 2.92 125163 3155 2 1117.497828 559.7573 Nucleoprotein TPR OS=Homo sapiens OX=9606 GN=TPR PE=1 SV=3 4.53 1270.9 - 586486 - - - -1.9257 - 1.869 0.466 - 279.8 1 2 0 -0.0022 10 0 0 0 2.76E+07 9.45E+06 - - - 4.2279 1 221125_WJC_METTL3_EV_vs_WT_F09.03157.03157.2 4.94E-08 20-Sep R.NDGAENSC[160.03]TER[166.11].D "sp|Q9Y5Q8|TF3C5_HUMAN,tr|Q5T7U1|Q5T7U1_HUMAN,tr|H7BY84|H7BY84_HUMAN" 3 1261.4869 0.52 125165 3157 2 1261.485938 631.7507 General transcription factor 3C polypeptide 5 OS=Homo sapiens OX=9606 GN=GTF3C5 PE=1 SV=2 4.14 1271.1 - 423475 - - - -0.7333 - 2.17 0.748 - 342.1 1 2 0 -0.0009 11 0 0 0 1.31E+06 2.52E+06 - - - 6.6613 0.9955 221125_WJC_METTL3_EV_vs_WT_F09.03158.03158.2 0.0576 12-Oct R.DRYDSDR.Y "sp|P23588|IF4B_HUMAN,tr|E7EX17|E7EX17_HUMAN,tr|F8VX11|F8VX11_HUMAN" 3 925.389 3.02 125166 3158 2 925.387975 463.7018 Eukaryotic translation initiation factor 4B OS=Homo sapiens OX=9606 GN=EIF4B PE=1 SV=2 4.43 1271.2 - 320319 - - - -1.0785 - 1.757 0.36 - 500.5 1 2 1 -0.001 7 0 0 0 2.81E+07 9.32E+06 - - - 3.4855 0.9999 221125_WJC_METTL3_EV_vs_WT_F09.03159.03159.2 8.39E-06 20-Oct R.NDGAENSC[160.03]TER.D "sp|Q9Y5Q8|TF3C5_HUMAN,tr|Q5T7U1|Q5T7U1_HUMAN,tr|H7BY84|H7BY84_HUMAN" 3 1251.4786 0.52 125167 3159 2 1251.477668 626.7466 General transcription factor 3C polypeptide 5 OS=Homo sapiens OX=9606 GN=GTF3C5 PE=1 SV=2 4.14 1271.4 - 244708 - - - -0.7391 - 1.971 0.552 - 498.1 1 2 0 -0.0009 11 0 0 0 1.31E+06 2.52E+06 - - - 4.9534 0.9809 221125_WJC_METTL3_EV_vs_WT_F09.03168.03168.2 0.0403 12-Oct R.DR[166.11]YDSDR[166.11].Y "sp|P23588|IF4B_HUMAN,tr|E7EX17|E7EX17_HUMAN,tr|F8VX11|F8VX11_HUMAN" 3 945.4055 3.02 125174 3168 2 945.402905 473.71 Eukaryotic translation initiation factor 4B OS=Homo sapiens OX=9606 GN=EIF4B PE=1 SV=2 4.43 1272.3 - 1.04E+06 - - - -2.7586 - 1.835 0.289 - 519.1 1 2 1 -0.0026 7 0 0 0 2.81E+07 9.32E+06 - - - 3.0982 0.9993 221125_WJC_METTL3_EV_vs_WT_F09.03169.03169.3 0.000873 Oct-36 K.INQAKPEC[160.03]GR.Q sp|Q9H8V3|ECT2_HUMAN 1 1171.5768 5.59 125175 3169 3 1171.572792 391.5329 Protein ECT2 OS=Homo sapiens OX=9606 GN=ECT2 PE=1 SV=4 8.22 1272.4 - 900540 - - - -3.4133 - 2.138 0.372 - 106.7 1 2 0 -0.004 10 0 0 0 5.47E+07 9.79E+06 - - - 4.9055 0.9998 221125_WJC_METTL3_EV_vs_WT_F09.03172.03172.2 0.00864 13/18 R.SGGGGYSQNR[166.11].W "sp|Q9BUJ2|HNRL1_HUMAN,tr|A0A0A0MRA5|A0A0A0MRA5_HUMAN,tr|M0R3F1|M0R3F1_HUMAN,tr|B7Z4B8|B7Z4B8_HUMAN" 4 991.4347 1.57 125178 3172 2 991.435355 496.7246 Heterogeneous nuclear ribonucleoprotein U-like protein 1 OS=Homo sapiens OX=9606 GN=HNRNPUL1 PE=1 SV=2 8.46 1272.8 - 664087 - - - 0.6697 - 2.817 0.358 - 852.3 1 2 0 0.0007 10 0 0 0 2.42E+08 1.54E+08 - - - 4.5759 0.968 221125_WJC_METTL3_EV_vs_WT_F09.03179.03179.2 2.45 14-Jul K.QESTEYRR.Q "sp|P08670|VIME_HUMAN,tr|B0YJC5|B0YJC5_HUMAN,tr|B0YJC4|B0YJC4_HUMAN" 3 1067.4996 1.86 125183 3179 2 1067.497354 534.7571 Vimentin OS=Homo sapiens OX=9606 GN=VIM PE=1 SV=4 6.14 1273.6 - 3.59E+07 - - - -2.0909 - 1.214 0.103 - 106.1 1 2 0 -0.0022 8 0 0 0 3.98E+08 2.14E+08 - - - 0.3859 0.9995 221125_WJC_METTL3_EV_vs_WT_F09.03180.03180.2 0.000255 13/18 R.SGGGGYSQNR.W "sp|Q9BUJ2|HNRL1_HUMAN,tr|A0A0A0MRA5|A0A0A0MRA5_HUMAN,tr|M0R3F1|M0R3F1_HUMAN,tr|B7Z4B8|B7Z4B8_HUMAN" 4 981.4264 1.57 125184 3180 2 981.423653 491.7205 Heterogeneous nuclear ribonucleoprotein U-like protein 1 OS=Homo sapiens OX=9606 GN=HNRNPUL1 PE=1 SV=2 8.46 1273.6 - 7.54E+06 - - - -2.8204 - 2.811 0.378 - 800 1 2 0 -0.0028 10 0 0 0 2.42E+08 1.54E+08 - - - 4.717 0.9679 221125_WJC_METTL3_EV_vs_WT_F09.03182.03182.2 0.0296 12-Sep R.DRENYDR.G "sp|P17844|DDX5_HUMAN,tr|J3KTA4|J3KTA4_HUMAN,tr|A0A0G2JLI4|A0A0G2JLI4_HUMAN" 3 966.4155 1.61 125186 3182 2 966.411854 484.215 Probable ATP-dependent RNA helicase DDX5 OS=Homo sapiens OX=9606 GN=DDX5 PE=1 SV=1 4.56 1273.7 - 2.61E+06 - - - -3.7955 - 1.823 0.325 - 293.6 1 2 1 -0.0037 7 0 0 0 3.42E+08 2.12E+08 - - - 3.343 0.8271 221125_WJC_METTL3_EV_vs_WT_F09.03183.03183.2 0.0413 14-Aug K.DKQTQLNR.G sp|P98175|RBM10_HUMAN 1 1001.5254 0.9 125187 3183 2 1001.520033 501.77 RNA-binding protein 10 OS=Homo sapiens OX=9606 GN=RBM10 PE=1 SV=3 8.75 1273.8 - 1.79E+06 - - - -5.3658 - 1.705 0.269 - 224.6 1 2 1 -0.0054 8 0 0 0 5.93E+06 6.59E+06 - - - 2.6354 0.9802 221125_WJC_METTL3_EV_vs_WT_F09.03186.03186.3 0.00104 13/36 R.EAEEAER[166.11]EER[166.11].K "sp|Q96HY6|DDRGK_HUMAN,tr|A0A0A0MRX2|A0A0A0MRX2_HUMAN" 2 1266.5591 0.34 125190 3186 3 1266.552416 423.1936 DDRGK domain-containing protein 1 OS=Homo sapiens OX=9606 GN=DDRGK1 PE=1 SV=2 4.21 1274.2 - 615067 - - - -5.2876 - 2.038 0.346 - 359.2 1 2 1 -0.0067 10 0 0 0 3.40E+06 1.01E+07 - - - 4.475 0.9994 221125_WJC_METTL3_EV_vs_WT_F09.03187.03187.2 0.01 16-Oct R.NQHLVSQQK.D sp|P12270|TPR_HUMAN 1 1080.5676 4.53 125191 3187 2 1080.564774 541.2911 Nucleoprotein TPR OS=Homo sapiens OX=9606 GN=TPR PE=1 SV=3 8.76 1274.3 - 433977 - - - -2.6208 - 2.128 0.417 - 539.7 1 2 0 -0.0028 9 0 0 0 5.01E+06 1.11E+06 - - - 4.3049 0.9989 221125_WJC_METTL3_EV_vs_WT_F09.03203.03203.2 0.00737 18-Nov K.K[136.11]VEGAPTQGR[166.11].K "sp|Q9P2E9|RRBP1_HUMAN,tr|A2A2S5|A2A2S5_HUMAN" 2 1059.5792 0.81 125203 3203 2 1059.575681 530.7969 Ribosome-binding protein 1 OS=Homo sapiens OX=9606 GN=RRBP1 PE=1 SV=5 8.75 1276.1 - 1.56E+06 - - - -3.2994 - 2.091 0.4 - 347.9 1 2 0 -0.0035 10 0 0 0 1.58E+07 1.96E+07 - - - 4.0533 0.9914 221125_WJC_METTL3_EV_vs_WT_F09.03207.03207.2 1.13 18-Nov R.LAESK[136.11]PNENR[166.11].L "sp|Q6KC79|NIPBL_HUMAN,tr|A0A590UJS4|A0A590UJS4_HUMAN" 2 1174.6061 1.51 125205 3207 2 1174.60295 588.3103 Nipped-B-like protein OS=Homo sapiens OX=9606 GN=NIPBL PE=1 SV=2 6.14 1276.6 - 472958 - - - -2.6988 - 1.741 0.143 - 511.3 1 2 0 -0.0032 10 0 0 0 1.32E+07 8.72E+06 - - - 1.6439 0.9996 221125_WJC_METTL3_EV_vs_WT_F09.03211.03211.2 2.09E-05 18-Sep K.TSDTETEPSK.T sp|P46013|KI67_HUMAN 1 1093.4775 1.12 125209 3211 2 1093.474777 547.746 Proliferation marker protein Ki-67 OS=Homo sapiens OX=9606 GN=MKI67 PE=1 SV=2 4.14 1277.1 - 471297 - - - -2.5021 - 1.846 0.522 - 309.5 1 2 0 -0.0027 10 0 0 0 1.13E+07 1.01E+07 - - - 4.6068 0.997 221125_WJC_METTL3_EV_vs_WT_F09.03215.03215.2 0.000909 22-Oct K.GNTPATGTTQGK[136.11].K "sp|Q9P2E9|RRBP1_HUMAN,tr|A2A2S5|A2A2S5_HUMAN,tr|A0A087WVV2|A0A087WVV2_HUMAN" 3 1139.5662 1.11 125211 3215 2 1139.560938 570.7904 Ribosome-binding protein 1 OS=Homo sapiens OX=9606 GN=RRBP1 PE=1 SV=5 8.75 1277.6 - 1.02E+06 - - - -4.6316 - 1.918 0.446 - 384.6 1 2 0 -0.0053 12 0 0 0 1.16E+08 1.04E+08 - - - 4.0471 0.9867 221125_WJC_METTL3_EV_vs_WT_F09.03222.03222.2 0.000238 16-Aug K.INHEGEVNR[166.11].A "sp|Q09028|RBBP4_HUMAN,sp|Q16576|RBBP7_HUMAN,tr|Q5JP01|Q5JP01_HUMAN,tr|E9PC52|E9PC52_HUMAN" 4 1076.5238 1.18 125216 3222 2 1076.519816 539.2692 Histone-binding protein RBBP4 OS=Homo sapiens OX=9606 GN=RBBP4 PE=1 SV=3 5.4 1278.4 - 450807 - - - -3.7389 - 1.42 0.25 - 246.4 1 2 0 -0.004 9 0 0 0 9.68E+06 8.21E+06 - - - 1.9007 0.9971 221125_WJC_METTL3_EV_vs_WT_F09.03224.03224.2 0.000533 20-Oct K.SEEEQSSSSVK[136.11].K "sp|P07910|HNRPC_HUMAN,tr|B4DY08|B4DY08_HUMAN,tr|G3V5V7|G3V5V7_HUMAN,tr|B2R5W2|B2R5W2_HUMAN,tr|G3V4C1|G3V4C1_HUMAN,tr|G3V2D6|G3V2D6_HUMAN,tr|G3V4W0|G3V4W0_HUMAN,tr|G3V2Q1|G3V2Q1_HUMAN" 8 1203.5346 1.57 125217 3224 2 1203.528278 602.7746 Heterogeneous nuclear ribonucleoproteins C1\C2 OS=Homo sapiens OX=9606 GN=HNRNPC PE=1 SV=4 4.25 1278.6 - 390538 - - - -5.2869 - 2.084 0.517 - 344.9 1 2 0 -0.0064 11 0 0 0 3.33E+08 2.12E+08 - - - 4.844 0.9565 221125_WJC_METTL3_EV_vs_WT_F09.03229.03229.2 1.01E-06 13/24 G.GSGGGYGGGSGSR.G "sp|P35527|K1C9_HUMAN,sp|P35527|K1C9_HUMAN,tr|K7EQQ3|K7EQQ3_HUMAN,tr|K7EQQ3|K7EQQ3_HUMAN" 4 1054.4428 0.18 125220 3229 2 1054.440303 528.2287 "Keratin, type I cytoskeletal 9 OS=Homo sapiens OX=9606 GN=KRT9 PE=1 SV=3" 8.75 1279.3 - 739520 - - - -2.3681 - 2.214 0.355 - 478.6 1 1 0 -0.0025 13 0 0 0 6.21E+06 3.52E+07 - - - 3.7021 0.9437 221125_WJC_METTL3_EV_vs_WT_F09.03232.03232.2 0.00775 14-Jul L.NHEGEVNR.A "sp|Q09028|RBBP4_HUMAN,sp|Q16576|RBBP7_HUMAN,tr|Q5JP01|Q5JP01_HUMAN,tr|E9PC52|E9PC52_HUMAN" 4 953.4315 1.82 125221 3232 2 953.430405 477.723 Histone-binding protein RBBP4 OS=Homo sapiens OX=9606 GN=RBBP4 PE=1 SV=3 5.4 1279.7 - 460936 - - - -1.1558 - 1.431 0.336 - 211.2 1 1 0 -0.0011 8 0 0 0 5.02E+06 2.76E+06 - - - 2.6032 0.9868 221125_WJC_METTL3_EV_vs_WT_F09.03234.03234.2 8.55E-05 24-Oct R.HSVVAGGGGGEGR[166.11].K sp|Q6PKG0|LARP1_HUMAN 1 1148.5562 2.07 125223 3234 2 1148.547442 575.2854 La-related protein 1 OS=Homo sapiens OX=9606 GN=LARP1 PE=1 SV=2 6.75 1279.9 - 147473 - - - -7.6278 - 2.128 0.522 - 270.7 1 2 0 -0.0088 13 0 0 0 2.60E+07 1.26E+07 - - - 4.8319 0.9969 221125_WJC_METTL3_EV_vs_WT_F09.03237.03237.2 0.569 16-Oct K.RFNDGSDEK.K "sp|P25705|ATPA_HUMAN,tr|K7EK77|K7EK77_HUMAN,tr|K7ENJ4|K7ENJ4_HUMAN" 3 1066.468 1.39 125224 3237 2 1066.466615 534.2413 "ATP synthase subunit alpha, mitochondrial OS=Homo sapiens OX=9606 GN=ATP5F1A PE=1 SV=1" 4.56 1280.4 - 1.84E+06 - - - -1.2537 - 1.667 0.156 - 456.7 1 2 0 -0.0013 9 0 0 0 4.19E+07 3.01E+07 - - - 1.6712 0.9974 221125_WJC_METTL3_EV_vs_WT_F09.03238.03238.2 2.99E-05 18-Nov K.TSDTETEPSK[136.11].T sp|P46013|KI67_HUMAN 1 1101.4917 1.11 125225 3238 2 1101.486338 551.7531 Proliferation marker protein Ki-67 OS=Homo sapiens OX=9606 GN=MKI67 PE=1 SV=2 4.14 1280.6 - 254759 - - - -4.8797 - 1.914 0.498 - 467.4 1 2 0 -0.0054 10 0 0 0 1.07E+07 9.58E+06 - - - 4.5296 1 221125_WJC_METTL3_EV_vs_WT_F09.03239.03239.3 0.000187 18/48 R.HSVVAGGGGGEGR[166.11].K sp|Q6PKG0|LARP1_HUMAN 1 1148.5562 0.86 125226 3239 3 1148.553573 383.8593 La-related protein 1 OS=Homo sapiens OX=9606 GN=LARP1 PE=1 SV=2 6.75 1280.6 - 1.13E+06 - - - -2.2898 - 3.51 0.49 - 797.3 1 2 0 -0.0026 13 0 0 0 3.80E+07 4.41E+07 - - - 7.4066 0.9993 221125_WJC_METTL3_EV_vs_WT_F09.03242.03242.2 9.51E-09 30-Oct K.ASGGQDGAASSAGAAK[136.11].R sp|O60287|NPA1P_HUMAN 1 1312.6099 1.14 125229 3242 2 1312.605581 657.3122 Nucleolar pre-ribosomal-associated protein 1 OS=Homo sapiens OX=9606 GN=URB1 PE=1 SV=4 5.88 1281 - 91171.2 - - - -3.2683 - 2.062 0.52 - 170.8 1 2 0 -0.0043 16 0 0 0 9.17E+05 8.07E+05 - - - 4.6596 0.86 221125_WJC_METTL3_EV_vs_WT_F09.03246.03246.2 0.0413 16-Aug R.EAQKELQEK.V sp|O43395|PRPF3_HUMAN 1 1101.5666 2.32 125231 3246 2 1101.562681 551.7906 U4\U6 small nuclear ribonucleoprotein Prp3 OS=Homo sapiens OX=9606 GN=PRPF3 PE=1 SV=2 4.79 1281.6 - 414360 - - - -3.5604 - 1.349 0.248 - 218.8 1 2 1 -0.0039 9 0 0 0 3.64E+07 1.57E+07 - - - 1.7376 0.9924 221125_WJC_METTL3_EV_vs_WT_F09.03249.03249.2 0.108 14-May R.HDSPEDVK.R "sp|P31948|STIP1_HUMAN,tr|H0YGI8|H0YGI8_HUMAN" 2 925.4141 1.34 125234 3249 2 925.413315 463.7143 Stress-induced-phosphoprotein 1 OS=Homo sapiens OX=9606 GN=STIP1 PE=1 SV=1 4.54 1281.9 - 210310 - - - -0.8753 - 0.971 0.263 - 105.6 1 2 0 -0.0008 8 0 0 0 2.33E+07 1.73E+07 - - - 0.8945 1 221125_WJC_METTL3_EV_vs_WT_F09.03253.03253.3 4.35E-07 13/48 K.GAHPSGGADDVAK[136.11].K sp|Q07065|CKAP4_HUMAN 1 1188.5615 1.24 125236 3253 3 1188.559295 397.1944 Cytoskeleton-associated protein 4 OS=Homo sapiens OX=9606 GN=CKAP4 PE=1 SV=2 5.21 1282.5 - 932519 - - - -1.8257 - 2.428 0.567 - 282.5 1 2 0 -0.0022 13 0 0 0 5.51E+07 4.46E+07 - - - 7.266 0.7902 221125_WJC_METTL3_EV_vs_WT_F09.03254.03254.2 0.00938 16-Jul T.PNNRPDAPK.E "sp|Q5TAP6|UT14C_HUMAN,sp|Q9BVJ6|UT14A_HUMAN" 2 1007.5148 8.05 125237 3254 2 1007.511137 504.7647 U3 small nucleolar RNA-associated protein 14 homolog C OS=Homo sapiens OX=9606 GN=UTP14C PE=1 SV=1 9.18 1282.6 - 243248 - - - -3.6774 - 1.611 0.328 - 163.6 1 1 0 -0.0037 9 0 0 0 4.51E+06 5.61E+05 - - - 2.842 0.9342 221125_WJC_METTL3_EV_vs_WT_F09.03257.03257.2 3.09E-05 24-Sep K.GAHPSGGADDVAK[136.11].K sp|Q07065|CKAP4_HUMAN 1 1188.5615 1.06 125240 3257 2 1188.555799 595.288 Cytoskeleton-associated protein 4 OS=Homo sapiens OX=9606 GN=CKAP4 PE=1 SV=2 5.21 1282.9 - 242747 - - - -4.7671 - 1.603 0.13 - 164.6 1 2 0 -0.0057 13 0 0 0 1.05E+07 9.93E+06 - - - 1.2105 0.9996 221125_WJC_METTL3_EV_vs_WT_F09.03258.03258.2 4.17E-06 24-Nov K.GAHPSGGADDVAK.K sp|Q07065|CKAP4_HUMAN 1 1180.5473 0.94 125241 3258 2 1180.54483 591.2809 Cytoskeleton-associated protein 4 OS=Homo sapiens OX=9606 GN=CKAP4 PE=1 SV=2 5.21 1283.1 - 200683 - - - -2.0626 - 2.019 0.465 - 263.4 1 2 0 -0.0024 13 0 0 0 1.05E+07 1.12E+07 - - - 4.278 0.9447 221125_WJC_METTL3_EV_vs_WT_F09.03259.03259.2 0.0005 22-Sep F.SSEAESGSPETK.K tr|A0A7P0MKV3|A0A7P0MKV3_HUMAN 1 1207.5204 1.16 125242 3259 2 1207.516614 604.7675 "28S ribosomal protein S22, mitochondrial OS=Homo sapiens OX=9606 GN=MRPS22 PE=1 SV=1" 4.25 1283.2 - 200038 - - - -3.1693 - 1.739 0.493 - 205.6 1 1 0 -0.0038 12 0 0 0 3.76E+06 3.24E+06 - - - 4.1369 0.7618 221125_WJC_METTL3_EV_vs_WT_F09.03260.03260.2 0.00356 20-Jun K.TQNANQAASER[166.11].L sp|P48552|NRIP1_HUMAN 1 1198.5566 -1 125243 3260 2 1199.555739 600.2856 Nuclear receptor-interacting protein 1 OS=Homo sapiens OX=9606 GN=NRIP1 PE=1 SV=2 5.66 1283.3 - 64040.6 - - - 833.621 - 1.311 0.376 - 83 1 2 0 0.9991 11 0 0 0 0.00E+00 0.00E+00 - - - 2.237 1 221125_WJC_METTL3_EV_vs_WT_F09.03262.03262.3 7.36E-07 23/48 R.HSVVAGGGGGEGR.K sp|Q6PKG0|LARP1_HUMAN 1 1138.5479 0.86 125244 3262 3 1138.54698 380.5233 La-related protein 1 OS=Homo sapiens OX=9606 GN=LARP1 PE=1 SV=2 6.75 1283.6 - 3.84E+06 - - - -0.837 - 3.603 0.594 - 1353.2 1 2 0 -0.001 13 0 0 0 3.80E+07 4.41E+07 - - - 8.6375 0.9958 221125_WJC_METTL3_EV_vs_WT_F09.03267.03267.2 0.000709 14-Aug K.QQQDQVDR.N "sp|Q15233|NONO_HUMAN,tr|A0A7I2V535|A0A7I2V535_HUMAN,tr|A0A7I2V4N2|A0A7I2V4N2_HUMAN,tr|A0A7I2V4K9|A0A7I2V4K9_HUMAN,tr|A0A7I2V464|A0A7I2V464_HUMAN,tr|A0A7P0MRW0|A0A7P0MRW0_HUMAN,tr|H7C367|H7C367_HUMAN,tr|A0A7I2V4J2|A0A7I2V4J2_HUMAN,tr|A0A7I2V5Y7|A0A7I2V5Y7_HUMAN,tr|C9JYS8|C9JYS8_HUMAN" 10 1015.4683 0.41 125248 3267 2 1015.466209 508.7414 Non-POU domain-containing octamer-binding protein OS=Homo sapiens OX=9606 GN=NONO PE=1 SV=4 4.21 1284.1 - 361141 - - - -2.0454 - 1.792 0.14 - 419.5 1 2 0 -0.0021 8 0 0 0 4.54E+06 1.11E+07 - - - 1.8337 0.9131 221125_WJC_METTL3_EV_vs_WT_F09.03269.03269.2 2.04 16-Jul K.GSPRPQAPK.A "sp|Q14978|NOLC1_HUMAN,tr|A0A0A0MRM9|A0A0A0MRM9_HUMAN" 2 936.5141 1.98 125250 3269 2 936.511799 469.2643 Nucleolar and coiled-body phosphoprotein 1 OS=Homo sapiens OX=9606 GN=NOLC1 PE=1 SV=2 11 1284.4 - 212243 - - - -2.4719 - 1.234 0.032 - 173.7 1 2 0 -0.0023 9 0 0 0 4.74E+07 2.40E+07 - - - -0.1151 0.9988 221125_WJC_METTL3_EV_vs_WT_F09.03275.03275.2 6.55E-05 14-Jul R.HDSPEDVK[136.11].R "sp|P31948|STIP1_HUMAN,tr|H0YGI8|H0YGI8_HUMAN" 2 933.4283 1.34 125253 3275 2 933.425467 467.7214 Stress-induced-phosphoprotein 1 OS=Homo sapiens OX=9606 GN=STIP1 PE=1 SV=1 4.54 1285.2 - 513467 - - - -3.0618 - 1.759 0.407 - 181 1 2 0 -0.0029 8 0 0 0 2.33E+07 1.73E+07 - - - 3.7495 0.9752 221125_WJC_METTL3_EV_vs_WT_F09.03276.03276.2 0.0549 18-Jul R.TPNNRPDAPK.E "sp|Q5TAP6|UT14C_HUMAN,sp|Q9BVJ6|UT14A_HUMAN" 2 1108.5625 2.6 125254 3276 2 1108.560414 555.2885 U3 small nucleolar RNA-associated protein 14 homolog C OS=Homo sapiens OX=9606 GN=UTP14C PE=1 SV=1 8.41 1285.3 - 320721 - - - -1.9007 - 1.285 0.099 - 104 1 2 0 -0.0021 10 0 0 0 1.17E+07 4.49E+06 - - - 0.4715 0.9997 221125_WJC_METTL3_EV_vs_WT_F09.03277.03277.2 0.017 16-Sep K.HEANNPQLK.E "sp|P31948|STIP1_HUMAN,tr|F5GXD8|F5GXD8_HUMAN,tr|F5H783|F5H783_HUMAN" 3 1049.5254 0.94 125255 3277 2 1049.52365 525.77 Stress-induced-phosphoprotein 1 OS=Homo sapiens OX=9606 GN=STIP1 PE=1 SV=1 6.75 1285.4 - 194659 - - - -1.6741 - 1.755 0.495 - 230.7 1 2 0 -0.0018 9 0 0 0 1.24E+07 1.32E+07 - - - 4.3238 0.996 221125_WJC_METTL3_EV_vs_WT_F09.03278.03278.2 0.0328 16-Jul K.GSPR[166.11]PQAPK[136.11].A "sp|Q14978|NOLC1_HUMAN,tr|A0A0A0MRM9|A0A0A0MRM9_HUMAN" 2 954.5366 1.98 125256 3278 2 954.533264 478.2756 Nucleolar and coiled-body phosphoprotein 1 OS=Homo sapiens OX=9606 GN=NOLC1 PE=1 SV=2 11 1285.6 - 181253 - - - -3.4781 - 1.467 0.358 - 183 1 2 0 -0.0033 9 0 0 0 4.74E+07 2.40E+07 - - - 2.7928 0.9998 221125_WJC_METTL3_EV_vs_WT_F09.03287.03287.2 0.000307 18-Nov R.QAQQAQNVQR.K "sp|Q9NQ55|SSF1_HUMAN,tr|A0A0B4J1V8|A0A0B4J1V8_HUMAN,tr|H7C446|H7C446_HUMAN,tr|A0A0A6YYI3|A0A0A6YYI3_HUMAN,tr|A8MV53|A8MV53_HUMAN" 5 1169.5901 1 125262 3287 2 1169.587526 585.8023 Suppressor of SWI4 1 homolog OS=Homo sapiens OX=9606 GN=PPAN PE=2 SV=1 9.75 1286.7 - 202997 - - - -2.2281 - 2.302 0.535 - 722.9 1 2 0 -0.0026 10 0 0 0 9.49E+06 9.54E+06 - - - 5.319 0.814 221125_WJC_METTL3_EV_vs_WT_F09.03295.03295.2 5.44 20-Mar -.MSDSEEESQDR.Q "sp|P51157|RAB28_HUMAN,tr|Q8WVF3|Q8WVF3_HUMAN" 2 1311.4885 1.35 125268 3295 2 1311.48591 656.7515 Ras-related protein Rab-28 OS=Homo sapiens OX=9606 GN=RAB28 PE=1 SV=2 3.83 1287.7 - 167612 - - - -1.9665 - 0.797 0.112 - 27.1 2 2 0 -0.0026 11 0 0 0 8.38E+06 6.19E+06 - - - -0.8809 0.9955 221125_WJC_METTL3_EV_vs_WT_F09.03297.03297.2 0.000129 18-Jul R.ITEADEK[136.11]NDR[166.11].T sp|Q9H2W6|RM46_HUMAN 1 1207.58 2.83 125270 3297 2 1207.577825 604.7973 "39S ribosomal protein L46, mitochondrial OS=Homo sapiens OX=9606 GN=MRPL46 PE=1 SV=1" 4.32 1288 - 169353 - - - -1.7721 - 1.66 0.475 - 196.8 1 2 1 -0.0021 10 0 0 0 9.54E+06 3.37E+06 - - - 3.9634 0.9998 221125_WJC_METTL3_EV_vs_WT_F09.03300.03300.2 0.000644 18-Nov R.QAQQAQNVQR[166.11].K "sp|Q9NQ55|SSF1_HUMAN,tr|A0A0B4J1V8|A0A0B4J1V8_HUMAN,tr|H7C446|H7C446_HUMAN,tr|A0A0A6YYI3|A0A0A6YYI3_HUMAN,tr|A8MV53|A8MV53_HUMAN" 5 1179.5984 1 125271 3300 2 1179.59683 590.8065 Suppressor of SWI4 1 homolog OS=Homo sapiens OX=9606 GN=PPAN PE=2 SV=1 9.75 1288.4 - 567059 - - - -1.3327 - 2.162 0.459 - 672.4 1 2 0 -0.0016 10 0 0 0 9.49E+06 9.54E+06 - - - 4.5829 0.9993 221125_WJC_METTL3_EV_vs_WT_F09.03303.03303.2 0.0283 16-Jul K.HQIEGNVSK.Q sp|Q14789|GOGB1_HUMAN 1 1010.5145 1.12 125274 3303 2 1010.51448 506.2645 Golgin subfamily B member 1 OS=Homo sapiens OX=9606 GN=GOLGB1 PE=1 SV=2 6.75 1288.8 - 152957 - - - -0.0277 - 1.2 0.43 - 133.2 1 2 0 0 9 0 0 0 3.16E+06 2.81E+06 - - - 2.7444 0.9998 221125_WJC_METTL3_EV_vs_WT_F09.03307.03307.2 1.69E-05 26-Nov K.VAGGAAPSKPASAK.K "sp|Q14978|NOLC1_HUMAN,tr|A0A0A0MRM9|A0A0A0MRM9_HUMAN" 2 1210.667 1.97 125276 3307 2 1210.66483 606.3408 Nucleolar and coiled-body phosphoprotein 1 OS=Homo sapiens OX=9606 GN=NOLC1 PE=1 SV=2 10 1289.3 - 398660 - - - -1.7808 - 2.185 0.549 - 308.1 1 2 0 -0.0022 14 0 0 0 8.64E+07 4.38E+07 - - - 5.0567 0.9862 221125_WJC_METTL3_EV_vs_WT_F09.03309.03309.2 1.02E-05 26-Dec G.GGSGGGYGGGSGSR.G "sp|P35527|K1C9_HUMAN,sp|P35527|K1C9_HUMAN,tr|K7EQQ3|K7EQQ3_HUMAN,tr|K7EQQ3|K7EQQ3_HUMAN" 4 1111.4643 78.36 125278 3309 2 1111.463089 556.7394 "Keratin, type I cytoskeletal 9 OS=Homo sapiens OX=9606 GN=KRT9 PE=1 SV=3" 8.75 1289.6 - 299671 - - - -1.0563 - 1.714 0.509 - 389.5 1 1 0 -0.0012 14 0 0 0 5.17E+06 6.60E+04 - - - 4.1523 0.9998 221125_WJC_METTL3_EV_vs_WT_F09.03310.03310.2 5.49E-05 26-Oct K.VAGGAAPSK[136.11]PASAK[136.11].K "sp|Q14978|NOLC1_HUMAN,tr|A0A0A0MRM9|A0A0A0MRM9_HUMAN" 2 1226.6954 1.97 125279 3310 2 1226.69361 614.355 Nucleolar and coiled-body phosphoprotein 1 OS=Homo sapiens OX=9606 GN=NOLC1 PE=1 SV=2 10 1289.7 - 188784 - - - -1.4478 - 1.953 0.508 - 251.9 1 2 0 -0.0018 14 0 0 0 8.64E+07 4.38E+07 - - - 4.4723 0.9994 221125_WJC_METTL3_EV_vs_WT_F09.03314.03314.3 0.02 13/52 K.VAGGAAPSK[136.11]PASAK[136.11].K "sp|Q14978|NOLC1_HUMAN,tr|A0A0A0MRM9|A0A0A0MRM9_HUMAN" 2 1226.6954 2.03 125281 3314 3 1226.691861 409.9057 Nucleolar and coiled-body phosphoprotein 1 OS=Homo sapiens OX=9606 GN=NOLC1 PE=1 SV=2 10 1290.3 - 4.02E+06 - - - -2.8736 - 2.26 0.362 - 183.2 1 2 0 -0.0035 14 0 0 0 8.18E+08 4.03E+08 - - - 4.7418 0.9791 221125_WJC_METTL3_EV_vs_WT_F09.03315.03315.2 0.0285 14-Aug R.VFK[136.11]EENQK[136.11].G "sp|Q9NYF8|BCLF1_HUMAN,tr|E9PKI6|E9PKI6_HUMAN,tr|A0A1W2PQ43|A0A1W2PQ43_HUMAN,tr|E9PK91|E9PK91_HUMAN,tr|E9PK09|E9PK09_HUMAN,tr|E9PQN2|E9PQN2_HUMAN" 6 1036.5524 2.31 125282 3315 2 1036.550689 519.2835 Bcl-2-associated transcription factor 1 OS=Homo sapiens OX=9606 GN=BCLAF1 PE=1 SV=2 6.11 1290.4 - 582975 - - - -1.6603 - 1.321 0.325 - 222.1 1 2 1 -0.0017 8 0 0 0 2.55E+07 1.11E+07 - - - 2.2805 0.9972 221125_WJC_METTL3_EV_vs_WT_F09.03319.03319.2 0.00109 22-Jun R.LC[160.03]SSSSSDTSSR[166.11].S "sp|Q86WB0|NIPA_HUMAN,tr|C9J0I9|C9J0I9_HUMAN" 2 1282.5335 0.001 125286 3319 2 1282.529724 642.274 Nuclear-interacting partner of ALK OS=Homo sapiens OX=9606 GN=ZC3HC1 PE=1 SV=1 5.83 1290.9 - 72047.3 - - - -2.9278 - 1.151 0.452 - 97 1 2 0 -0.0038 12 0 0 0 0.00E+00 7.75E+05 - - - 2.7483 0.9999 221125_WJC_METTL3_EV_vs_WT_F09.03322.03322.3 0.000106 15/52 K.VAGGAAPSKPASAK.K "sp|Q14978|NOLC1_HUMAN,tr|A0A0A0MRM9|A0A0A0MRM9_HUMAN" 2 1210.667 2.03 125287 3322 3 1210.664435 404.5629 Nucleolar and coiled-body phosphoprotein 1 OS=Homo sapiens OX=9606 GN=NOLC1 PE=1 SV=2 10 1291.3 - 1.26E+07 - - - -2.1071 - 2.411 0.44 - 249.3 1 2 0 -0.0026 14 0 0 0 8.17E+08 4.03E+08 - - - 5.7836 0.9904 221125_WJC_METTL3_EV_vs_WT_F09.03324.03324.2 7.37E-07 13/24 V.AGGAAPSKPASAK.K "sp|Q14978|NOLC1_HUMAN,tr|A0A0A0MRM9|A0A0A0MRM9_HUMAN" 2 1111.5986 1.38 125289 3324 2 1111.59987 556.8066 Nucleolar and coiled-body phosphoprotein 1 OS=Homo sapiens OX=9606 GN=NOLC1 PE=1 SV=2 10 1291.6 - 631866 - - - 1.1677 - 2.501 0.487 - 609.8 1 1 0 0.0013 13 0 0 0 5.13E+07 3.71E+07 - - - 4.9903 0.9985 221125_WJC_METTL3_EV_vs_WT_F09.03326.03326.3 0.00857 Sep-40 K.IQNNDNVGK[136.11]PK[136.11].S "sp|Q08170|SRSF4_HUMAN,tr|A0A0D9SEM4|A0A0D9SEM4_HUMAN" 2 1241.6699 1.26 125291 3326 3 1241.665702 414.8972 Serine\arginine-rich splicing factor 4 OS=Homo sapiens OX=9606 GN=SRSF4 PE=1 SV=2 8.59 1291.8 - 418011 - - - -3.3801 - 1.913 0.346 - 85.9 1 2 0 -0.0042 11 0 0 0 1.18E+07 9.36E+06 - - - 4.2392 0.994 221125_WJC_METTL3_EV_vs_WT_F09.03327.03327.2 0.338 16-Jul R.NSTIENTRR.H "sp|Q99717|SMAD5_HUMAN,sp|O15198|SMAD9_HUMAN,sp|Q15797|SMAD1_HUMAN,tr|H0YAK7|H0YAK7_HUMAN" 4 1089.5527 1.77 125292 3327 2 1089.555347 545.7836 Mothers against decapentaplegic homolog 5 OS=Homo sapiens OX=9606 GN=SMAD5 PE=1 SV=1 9.6 1292 - 404620 - - - 2.4441 - 1.561 0.202 - 85.6 1 2 0 0.0027 9 0 0 0 1.87E+07 1.06E+07 - - - 1.8205 0.9999 221125_WJC_METTL3_EV_vs_WT_F09.03329.03329.2 0.000508 18-Aug R.SEENEEDC[160.03]SR.E "sp|Q6ZWJ1|STXB4_HUMAN,tr|E7EPP7|E7EPP7_HUMAN" 2 1253.4466 3.91 125294 3329 2 1253.447762 627.7306 Syntaxin-binding protein 4 OS=Homo sapiens OX=9606 GN=STXBP4 PE=1 SV=2 3.91 1292.2 - 87109.8 - - - 0.9079 - 1.758 0.648 - 261.4 1 2 0 0.0011 10 0 0 0 4.68E+05 1.20E+05 - - - 5.4016 0.9871 221125_WJC_METTL3_EV_vs_WT_F09.03335.03335.2 6.32E-06 22-Dec A.GGAAPSK[136.11]PASAK[136.11].K "sp|Q14978|NOLC1_HUMAN,tr|A0A0A0MRM9|A0A0A0MRM9_HUMAN" 2 1056.5899 2.24 125298 3335 2 1056.588328 529.3022 Nucleolar and coiled-body phosphoprotein 1 OS=Homo sapiens OX=9606 GN=NOLC1 PE=1 SV=2 10 1292.9 - 713431 - - - -1.4481 - 2.028 0.495 - 395 1 1 0 -0.0015 12 0 0 0 4.55E+07 2.03E+07 - - - 4.557 0.9997 221125_WJC_METTL3_EV_vs_WT_F09.03336.03336.3 0.0206 Dec-48 K.KPAAAAAPGTAEK.L "sp|P50454|SERPH_HUMAN,tr|E9PNX1|E9PNX1_HUMAN,tr|E9PIG2|E9PIG2_HUMAN,tr|E9PPV6|E9PPV6_HUMAN,tr|E9PR70|E9PR70_HUMAN,tr|E9PMI5|E9PMI5_HUMAN,tr|E9PRS3|E9PRS3_HUMAN,tr|E9PJH8|E9PJH8_HUMAN,tr|E9PK86|E9PK86_HUMAN,tr|E9PQ34|E9PQ34_HUMAN" 10 1181.6404 1.75 125299 3336 3 1181.639839 394.8874 Serpin H1 OS=Homo sapiens OX=9606 GN=SERPINH1 PE=1 SV=2 8.59 1293.1 - 595715 - - - -0.5061 - 2.154 0.323 - 242.7 1 2 0 -0.0006 13 0 0 0 4.94E+07 2.82E+07 - - - 4.2214 0.9997 221125_WJC_METTL3_EV_vs_WT_F09.03338.03338.2 0.00815 18-Sep R.EHC[160.03]PAGQPVK.V "sp|Q6P2Q9|PRP8_HUMAN,tr|I3L0J9|I3L0J9_HUMAN" 2 1121.5288 0.72 125301 3338 2 1121.52815 561.7717 Pre-mRNA-processing-splicing factor 8 OS=Homo sapiens OX=9606 GN=PRPF8 PE=1 SV=2 6.83 1293.3 - 330607 - - - -0.5599 - 1.884 0.4 - 354.2 1 2 0 -0.0006 10 0 0 0 5.28E+06 7.35E+06 - - - 3.7632 0.9647 221125_WJC_METTL3_EV_vs_WT_F09.03345.03345.2 0.285 12-Sep R.QREEYER.A sp|P12270|TPR_HUMAN 1 1008.4625 1.8 125306 3345 2 1008.460325 505.2385 Nucleoprotein TPR OS=Homo sapiens OX=9606 GN=TPR PE=1 SV=3 4.79 1294.2 - 634562 - - - -2.129 - 1.692 0.188 - 248.9 1 2 1 -0.0021 7 0 0 0 5.81E+06 3.23E+06 - - - 2.0953 0.9994 221125_WJC_METTL3_EV_vs_WT_F09.03347.03347.2 4.30E-05 13/24 R.SVSSSSTASASAK.K "sp|Q16836|HCDH_HUMAN,tr|A0A804HJW7|A0A804HJW7_HUMAN,tr|A0A1W2PP40|A0A1W2PP40_HUMAN,tr|E9PF18|E9PF18_HUMAN,tr|A0A0A0MSE2|A0A0A0MSE2_HUMAN,tr|A0A1W2PQV5|A0A1W2PQV5_HUMAN,tr|J3KR89|J3KR89_HUMAN,tr|A0A1W2PNM1|A0A1W2PNM1_HUMAN,tr|A0A1W2PQ78|A0A1W2PQ78_HUMAN" 9 1168.5572 3.85 125308 3347 2 1168.55371 585.2859 "Hydroxyacyl-coenzyme A dehydrogenase, mitochondrial OS=Homo sapiens OX=9606 GN=HADH PE=1 SV=3" 8.47 1294.5 - 445774 - - - -2.9532 - 2.448 0.428 - 359.1 1 2 0 -0.0035 13 0 0 0 4.83E+06 1.25E+06 - - - 4.4989 0.8775 221125_WJC_METTL3_EV_vs_WT_F09.03350.03350.3 0.000694 Nov-36 F.LC[160.03]SGSHQVQR.D "sp|Q9Y4A5|TRRAP_HUMAN,tr|A0A2R8YFJ4|A0A2R8YFJ4_HUMAN,tr|H0Y4W2|H0Y4W2_HUMAN,tr|F2Z2U4|F2Z2U4_HUMAN" 4 1170.5564 1.73 125309 3350 3 1170.550972 391.1927 Transformation\transcription domain-associated protein OS=Homo sapiens OX=9606 GN=TRRAP PE=1 SV=3 8.26 1294.9 - 637838 - - - -4.6286 - 2.126 0.393 - 140.9 1 1 0 -0.0054 10 0 0 0 5.63E+06 3.25E+06 - - - 5.1228 1 221125_WJC_METTL3_EV_vs_WT_F09.03352.03352.2 9.76E-07 15/24 K.K[136.11]PAAAAAPGTAEK[136.11].L "sp|P50454|SERPH_HUMAN,tr|E9PNX1|E9PNX1_HUMAN,tr|E9PIG2|E9PIG2_HUMAN,tr|E9PPV6|E9PPV6_HUMAN,tr|E9PR70|E9PR70_HUMAN,tr|E9PMI5|E9PMI5_HUMAN,tr|E9PRS3|E9PRS3_HUMAN,tr|E9PJH8|E9PJH8_HUMAN,tr|E9PK86|E9PK86_HUMAN,tr|E9PQ34|E9PQ34_HUMAN" 10 1197.6688 2.13 125311 3352 2 1197.665635 599.8417 Serpin H1 OS=Homo sapiens OX=9606 GN=SERPINH1 PE=1 SV=2 8.59 1295.1 - 387266 - - - -2.6735 - 3.438 0.606 - 645.1 1 2 0 -0.0032 13 0 0 0 1.60E+07 7.49E+06 - - - 6.6853 0.9995 221125_WJC_METTL3_EV_vs_WT_F09.03353.03353.2 0.00335 22-Aug K.EGNNPAENGDAK.T sp|P05204|HMGN2_HUMAN 1 1214.5164 1.17 125312 3353 2 1214.516351 608.2655 Non-histone chromosomal protein HMG-17 OS=Homo sapiens OX=9606 GN=HMGN2 PE=1 SV=3 4.14 1295.2 - 1.05E+06 - - - -0.0058 - 1.264 0.462 - 151.4 1 2 0 0 12 0 0 0 5.36E+07 4.56E+07 - - - 3.0698 0.9997 221125_WJC_METTL3_EV_vs_WT_F09.03358.03358.2 0.000293 20-Nov R.TSTSSSSVQAR[166.11].R "sp|Q9UKV3|ACINU_HUMAN,tr|S4R3H4|S4R3H4_HUMAN,tr|E7EQT4|E7EQT4_HUMAN" 3 1119.5395 1.27 125315 3358 2 1119.537614 560.7771 Apoptotic chromatin condensation inducer in the nucleus OS=Homo sapiens OX=9606 GN=ACIN1 PE=1 SV=2 9.41 1295.9 - 514634 - - - -1.7293 - 2.076 0.474 - 533.7 1 2 0 -0.0019 11 0 0 0 4.90E+07 3.87E+07 - - - 4.5174 0.9899 221125_WJC_METTL3_EV_vs_WT_F09.03359.03359.2 0.0364 14-Jul R.DYK[136.11]DEQGR[166.11].L "sp|Q86U86|PB1_HUMAN,tr|H0Y5B5|H0Y5B5_HUMAN,tr|E7EVG2|E7EVG2_HUMAN,tr|C9JPI5|C9JPI5_HUMAN,tr|C9JQF1|C9JQF1_HUMAN,tr|C9JCJ2|C9JCJ2_HUMAN,tr|C9J053|C9J053_HUMAN" 7 1027.469 1.15 125316 3359 2 1027.467443 514.7418 Protein polybromo-1 OS=Homo sapiens OX=9606 GN=PBRM1 PE=1 SV=1 4.56 1296.1 - 357165 - - - -1.4745 - 1.278 0.416 - 160.7 1 2 1 -0.0015 8 0 0 0 6.50E+06 5.65E+06 - - - 2.8529 1 221125_WJC_METTL3_EV_vs_WT_F09.03364.03364.3 1.85E-05 13/48 K.K[136.11]PAAAAAPGTAEK[136.11].L "sp|P50454|SERPH_HUMAN,tr|E9PNX1|E9PNX1_HUMAN,tr|E9PIG2|E9PIG2_HUMAN,tr|E9PPV6|E9PPV6_HUMAN,tr|E9PR70|E9PR70_HUMAN,tr|E9PMI5|E9PMI5_HUMAN,tr|E9PRS3|E9PRS3_HUMAN,tr|E9PJH8|E9PJH8_HUMAN,tr|E9PK86|E9PK86_HUMAN,tr|E9PQ34|E9PQ34_HUMAN" 10 1197.6688 1.9 125319 3364 3 1197.666313 400.2302 Serpin H1 OS=Homo sapiens OX=9606 GN=SERPINH1 PE=1 SV=2 8.59 1296.7 - 2.38E+06 - - - -2.1074 - 2.526 0.515 - 332.1 1 2 0 -0.0025 13 0 0 0 4.92E+07 2.59E+07 - - - 6.7934 0.9984 221125_WJC_METTL3_EV_vs_WT_F09.03368.03368.2 0.00159 18-Nov R.KGAAPTPPGK.T "sp|Q13428|TCOF_HUMAN,tr|H0YAB7|H0YAB7_HUMAN,tr|E7ETY2|E7ETY2_HUMAN,tr|H0Y8Y7|H0Y8Y7_HUMAN,tr|A0A3B3IS06|A0A3B3IS06_HUMAN,tr|A0A6I8PRA0|A0A6I8PRA0_HUMAN" 6 922.5236 1.03 125323 3368 2 922.520655 462.2691 Treacle protein OS=Homo sapiens OX=9606 GN=TCOF1 PE=1 SV=3 10 1297.2 - 431292 - - - -3.2097 - 2.019 0.344 - 395.2 1 2 0 -0.003 10 0 0 0 1.14E+07 1.10E+07 - - - 3.542 1 221125_WJC_METTL3_EV_vs_WT_F09.03373.03373.2 2.25E-05 19/24 K.KPAAAAAPGTAEK.L "sp|P50454|SERPH_HUMAN,tr|E9PNX1|E9PNX1_HUMAN,tr|E9PIG2|E9PIG2_HUMAN,tr|E9PPV6|E9PPV6_HUMAN,tr|E9PR70|E9PR70_HUMAN,tr|E9PMI5|E9PMI5_HUMAN,tr|E9PRS3|E9PRS3_HUMAN,tr|E9PJH8|E9PJH8_HUMAN,tr|E9PK86|E9PK86_HUMAN,tr|E9PQ34|E9PQ34_HUMAN" 10 1181.6404 2.13 125326 3373 2 1181.637967 591.8275 Serpin H1 OS=Homo sapiens OX=9606 GN=SERPINH1 PE=1 SV=2 8.59 1297.9 - 1.02E+06 - - - -2.0903 - 3.795 0.595 - 1213.7 1 2 0 -0.0025 13 0 0 0 1.60E+07 7.49E+06 - - - 6.8578 0.9999 221125_WJC_METTL3_EV_vs_WT_F09.03374.03374.3 0.000161 17/44 K.QIGANAHGAGSR.S sp|Q8TEK3|DOT1L_HUMAN 1 1137.5639 0.91 125327 3374 3 1137.560982 380.1952 "Histone-lysine N-methyltransferase, H3 lysine-79 specific OS=Homo sapiens OX=9606 GN=DOT1L PE=1 SV=3" 9.76 1298 - 658760 - - - -2.581 - 2.623 0.456 - 478 1 2 0 -0.0029 12 0 0 0 6.14E+06 6.74E+06 - - - 6.2961 0.9879 221125_WJC_METTL3_EV_vs_WT_F09.03379.03379.2 0.00085 22-Aug H.LQQDGQTGSGQR.S sp|Q14157|UBP2L_HUMAN 1 1273.6011 4.28 125332 3379 2 1273.600426 637.8078 Ubiquitin-associated protein 2-like OS=Homo sapiens OX=9606 GN=UBAP2L PE=1 SV=2 5.84 1298.6 - 147570 - - - -0.5221 - 1.825 0.47 - 250.6 1 1 0 -0.0007 12 0 0 0 1.23E+06 2.88E+05 - - - 4.0951 1 221125_WJC_METTL3_EV_vs_WT_F09.03386.03386.2 2.73E-07 20-Oct R.TSTSSSSVQAR.R "sp|Q9UKV3|ACINU_HUMAN,tr|S4R3H4|S4R3H4_HUMAN,tr|E7EQT4|E7EQT4_HUMAN" 3 1109.5313 1.27 125337 3386 2 1109.529719 555.7729 Apoptotic chromatin condensation inducer in the nucleus OS=Homo sapiens OX=9606 GN=ACIN1 PE=1 SV=2 9.41 1299.5 - 6.54E+06 - - - -1.4069 - 2.234 0.621 - 496.4 1 2 0 -0.0016 11 0 0 0 4.90E+07 3.87E+07 - - - 5.8017 0.9943 221125_WJC_METTL3_EV_vs_WT_F09.03390.03390.3 0.342 Nov-44 K.QIGANAHGAGSR[166.11].S sp|Q8TEK3|DOT1L_HUMAN 1 1147.5722 0.95 125341 3390 3 1147.569972 383.5313 "Histone-lysine N-methyltransferase, H3 lysine-79 specific OS=Homo sapiens OX=9606 GN=DOT1L PE=1 SV=3" 9.76 1299.9 - 495131 - - - -1.931 - 1.586 0.24 - 126.7 1 2 0 -0.0022 12 0 0 0 5.73E+06 6.04E+06 - - - 2.4936 0.9762 221125_WJC_METTL3_EV_vs_WT_F09.03393.03393.2 0.127 14-Jul K.NYDPQK[136.11]DK[136.11].R sp|P62906|RL10A_HUMAN 1 1022.5004 1.28 125344 3393 2 1022.49862 512.2575 60S ribosomal protein L10a OS=Homo sapiens OX=9606 GN=RPL10A PE=1 SV=2 5.96 1300.3 - 446102 - - - -1.7154 - 1.526 0.255 - 221.3 1 2 1 -0.0018 8 0 0 0 6.48E+06 5.07E+06 - - - 2.1986 0.9995 221125_WJC_METTL3_EV_vs_WT_F09.03394.03394.2 0.0022 16-Sep R.SGHGTEFNK.Q "sp|Q14966|ZN638_HUMAN,tr|A0A096LPB4|A0A096LPB4_HUMAN,tr|A0A096LNX0|A0A096LNX0_HUMAN,tr|A0A096LPI0|A0A096LPI0_HUMAN,tr|A0A096LNR2|A0A096LNR2_HUMAN" 5 975.441 0.51 125345 3394 2 975.438281 488.7278 Zinc finger protein 638 OS=Homo sapiens OX=9606 GN=ZNF638 PE=1 SV=2 6.47 1300.4 - 353066 - - - -2.7967 - 1.786 0.553 - 225.6 1 2 0 -0.0027 9 0 0 0 6.36E+06 1.25E+07 - - - 4.8025 1 221125_WJC_METTL3_EV_vs_WT_F09.03398.03398.2 2.23E-08 13/22 R.LTNGPSNGSSSR.Q sp|Q15007|FL2D_HUMAN 1 1175.5531 0.53 125347 3398 2 1175.553527 588.7838 Pre-mRNA-splicing regulator WTAP OS=Homo sapiens OX=9606 GN=WTAP PE=1 SV=2 9.75 1301 - 1.29E+06 - - - 0.3819 - 2.451 0.659 - 657.5 1 2 0 0.0004 12 0 0 0 2.20E+07 4.17E+07 - - - 6.2671 0.9886 221125_WJC_METTL3_EV_vs_WT_F09.03403.03403.2 1.34E-05 20-Oct K.PAGGPK[136.11]PPSGK[136.11].K "sp|P50990|TCPQ_HUMAN,tr|H7C2U0|H7C2U0_HUMAN" 2 1007.5735 0.55 125352 3403 2 1007.572766 504.794 T-complex protein 1 subunit theta OS=Homo sapiens OX=9606 GN=CCT8 PE=1 SV=4 10.02 1301.5 - 612725 - - - -0.7086 - 1.936 0.463 - 263 1 1 0 -0.0007 11 0 0 0 1.30E+07 2.36E+07 - - - 4.2476 0.9966 221125_WJC_METTL3_EV_vs_WT_F09.03411.03411.2 9.08E-05 16-Aug K.DKNTDTLSK.K sp|P20930|FILA_HUMAN 1 1020.5088 897.8 125358 3411 2 1020.508687 511.2617 Filaggrin OS=Homo sapiens OX=9606 GN=FLG PE=1 SV=3 5.96 1302.4 - 872307 - - - -0.0657 - 1.943 0.352 - 196.1 1 2 1 -0.0001 9 0 0 0 8.66E+07 9.64E+04 - - - 3.5625 0.9464 221125_WJC_METTL3_EV_vs_WT_F09.03414.03414.2 0.0175 14-Oct S.PQQIDHAK.Q "sp|Q92945|FUBP2_HUMAN,tr|M0R3J3|M0R3J3_HUMAN,tr|M0R0C6|M0R0C6_HUMAN,tr|A0A087WTP3|A0A087WTP3_HUMAN" 4 935.4825 1.54 125361 3414 2 935.480809 468.7485 Far upstream element-binding protein 2 OS=Homo sapiens OX=9606 GN=KHSRP PE=1 SV=4 7.17 1302.8 - 420706 - - - -1.7852 - 1.973 0.26 - 302.6 1 1 0 -0.0017 8 0 0 0 1.14E+07 7.43E+06 - - - 3.0103 0.9998 221125_WJC_METTL3_EV_vs_WT_F09.03415.03415.2 0.00146 18-Sep R.GSPQQIDHAK[136.11].Q "sp|Q92945|FUBP2_HUMAN,tr|M0R3J3|M0R3J3_HUMAN,tr|M0R0C6|M0R0C6_HUMAN,tr|A0A087WTP3|A0A087WTP3_HUMAN" 4 1087.5502 3.58 125362 3415 2 1087.550593 544.7824 Far upstream element-binding protein 2 OS=Homo sapiens OX=9606 GN=KHSRP PE=1 SV=4 6.74 1302.9 - 334330 - - - 0.3871 - 1.692 0.5 - 259.4 1 2 0 0.0004 10 0 0 0 2.72E+07 7.59E+06 - - - 4.2018 0.9996 221125_WJC_METTL3_EV_vs_WT_F09.03422.03422.2 2.14E-05 18-Dec K.KGEGAPIQGK.K "sp|Q9P2E9|RRBP1_HUMAN,tr|V9GY78|V9GY78_HUMAN" 2 983.54 0.04 125366 3422 2 983.537283 492.7773 Ribosome-binding protein 1 OS=Homo sapiens OX=9606 GN=RRBP1 PE=1 SV=5 8.59 1303.7 - 1.22E+06 - - - -2.7564 - 2.491 0.478 - 450.4 1 2 0 -0.0027 10 0 0 0 1.63E+07 3.69E+08 - - - 5.1182 0.9997 221125_WJC_METTL3_EV_vs_WT_F09.03423.03423.2 0.0295 13/18 K.K[136.11]GEGAPIQGK[136.11].K "sp|Q9P2E9|RRBP1_HUMAN,tr|V9GY78|V9GY78_HUMAN" 2 999.5684 0.04 125367 3423 2 999.565846 500.7915 Ribosome-binding protein 1 OS=Homo sapiens OX=9606 GN=RRBP1 PE=1 SV=5 8.59 1303.8 - 1.13E+06 - - - -2.5491 - 2.848 0.463 - 523.2 1 2 0 -0.0025 10 0 0 0 1.65E+07 4.54E+08 - - - 5.3813 1 221125_WJC_METTL3_EV_vs_WT_F09.03429.03429.2 2.34E-05 14/20 R.HLQEASATDGK.G "sp|Q5VW38|GP107_HUMAN,tr|G5E994|G5E994_HUMAN" 2 1155.552 0.64 125373 3429 2 1155.54987 578.7833 Protein GPR107 OS=Homo sapiens OX=9606 GN=GPR107 PE=1 SV=1 5.32 1304.6 - 340701 - - - -1.8571 - 2.698 0.565 - 559.9 1 2 0 -0.0021 11 0 0 0 6.27E+06 9.83E+06 - - - 5.8984 0.9999 221125_WJC_METTL3_EV_vs_WT_F09.03434.03434.2 0.0484 16-Dec K.HGLAHDEMK.S "sp|Q9Y2W1|TR150_HUMAN,tr|A0A3B3ITZ9|A0A3B3ITZ9_HUMAN" 2 1036.476 2.69 125375 3434 2 1036.474885 519.2453 Thyroid hormone receptor-associated protein 3 OS=Homo sapiens OX=9606 GN=THRAP3 PE=1 SV=2 5.99 1305.3 - 6.03E+06 - - - -1.0893 - 2.161 0.497 - 422.1 1 2 0 -0.0011 9 0 0 0 1.19E+08 4.42E+07 - - - 4.9408 0.9996 221125_WJC_METTL3_EV_vs_WT_F09.03436.03436.2 3.81E-06 16-Dec K.HTTDLDASK.L "sp|P17540|KCRS_HUMAN,sp|P12532|KCRU_HUMAN,tr|C9JSQ1|C9JSQ1_HUMAN,tr|D6RHV3|D6RHV3_HUMAN,tr|D6R998|D6R998_HUMAN,tr|C9JT96|C9JT96_HUMAN,tr|C9J8F6|C9J8F6_HUMAN,tr|F8WCN3|F8WCN3_HUMAN,tr|C9J6W7|C9J6W7_HUMAN" 9 986.4669 0.6 125377 3436 2 986.464183 494.2407 "Creatine kinase S-type, mitochondrial OS=Homo sapiens OX=9606 GN=CKMT2 PE=1 SV=2" 5.21 1305.4 - 1.84E+06 - - - -2.7431 - 2.275 0.517 - 382.2 1 2 0 -0.0027 9 0 0 0 2.51E+07 4.16E+07 - - - 5.2367 0.9997 221125_WJC_METTL3_EV_vs_WT_F09.03439.03439.2 8.03E-05 16-Sep R.SQSGGYSDR[166.11].S "sp|Q14011|CIRBP_HUMAN,tr|F6WMK9|F6WMK9_HUMAN,tr|K7EMY9|K7EMY9_HUMAN,tr|K7EQR7|K7EQR7_HUMAN,tr|K7EPM4|K7EPM4_HUMAN,tr|D6W5Y5|D6W5Y5_HUMAN" 6 965.4078 0.92 125380 3439 2 965.406285 483.7112 Cold-inducible RNA-binding protein OS=Homo sapiens OX=9606 GN=CIRBP PE=1 SV=1 5.55 1305.8 - 669090 - - - -1.5776 - 1.841 0.492 - 358.5 1 2 0 -0.0015 9 0 0 0 1.94E+07 2.10E+07 - - - 4.4401 0.9883 221125_WJC_METTL3_EV_vs_WT_F09.03440.03440.2 0.000377 18-Oct K.ADK[136.11]LAEEHSS.- sp|P06576|ATPB_HUMAN 1 1093.5131 2.45 125381 3440 2 1093.514667 547.7638 "ATP synthase subunit beta, mitochondrial OS=Homo sapiens OX=9606 GN=ATP5F1B PE=1 SV=3" 4.65 1305.9 - 617199 - - - 1.4174 - 1.695 0.306 - 185.4 1 2 1 0.0015 10 0 0 0 2.05E+07 8.39E+06 - - - 2.7736 0.9983 221125_WJC_METTL3_EV_vs_WT_F09.03446.03446.2 0.000723 16-Nov K.HTTDLDASK[136.11].L "sp|P17540|KCRS_HUMAN,sp|P12532|KCRU_HUMAN,tr|C9JSQ1|C9JSQ1_HUMAN,tr|D6RHV3|D6RHV3_HUMAN,tr|D6R998|D6R998_HUMAN,tr|C9JT96|C9JT96_HUMAN,tr|C9J8F6|C9J8F6_HUMAN,tr|F8WCN3|F8WCN3_HUMAN,tr|C9J6W7|C9J6W7_HUMAN" 9 994.4811 0.79 125385 3446 2 994.476652 498.2478 "Creatine kinase S-type, mitochondrial OS=Homo sapiens OX=9606 GN=CKMT2 PE=1 SV=2" 5.21 1306.7 - 2.89E+06 - - - -4.4616 - 1.933 0.518 - 283.2 1 2 0 -0.0044 9 0 0 0 3.43E+07 4.35E+07 - - - 4.7723 0.9892 221125_WJC_METTL3_EV_vs_WT_F09.03448.03448.2 0.0773 14-Nov K.LK[136.11]EDK[136.11]LEK[136.11].Q "sp|Q8ND56|LS14A_HUMAN,sp|Q07866|KLC1_HUMAN,tr|G3V5R9|G3V5R9_HUMAN,tr|G3V3H3|G3V3H3_HUMAN,tr|G3V2P7|G3V2P7_HUMAN,tr|F8W6L3|F8W6L3_HUMAN,tr|E7EVH7|E7EVH7_HUMAN,tr|A0A140TA76|A0A140TA76_HUMAN,tr|K7EMZ9|K7EMZ9_HUMAN,tr|G3V2E7|G3V2E7_HUMAN,tr|G5E9S8|G5E9S8_HUMAN" 11 1025.6183 0.97 125387 3448 2 1025.616078 513.8164 Protein LSM14 homolog A OS=Homo sapiens OX=9606 GN=LSM14A PE=1 SV=3 6.18 1306.8 - 2.19E+06 - - - -2.1772 - 2.025 0.283 - 307.2 1 2 2 -0.0022 8 0 0 0 5.18E+08 5.36E+08 - - - 3.2585 0.8312 221125_WJC_METTL3_EV_vs_WT_F09.03456.03456.3 0.00709 Oct-40 K.VPASQPRPESK.P "sp|Q13283|G3BP1_HUMAN,tr|A0A7I2V5M7|A0A7I2V5M7_HUMAN,tr|A0A7P0P2U7|A0A7P0P2U7_HUMAN,tr|A0A7I2YQU8|A0A7I2YQU8_HUMAN,tr|A0A7I2V548|A0A7I2V548_HUMAN,tr|A0A7I2YQN9|A0A7I2YQN9_HUMAN" 6 1194.6357 1.16 125392 3456 3 1194.636746 399.2192 Ras GTPase-activating protein-binding protein 1 OS=Homo sapiens OX=9606 GN=G3BP1 PE=1 SV=1 8.72 1307.8 - 763433 - - - 0.8873 - 1.81 0.239 - 120 1 1 0 0.0011 11 0 0 0 9.16E+06 7.90E+06 - - - 2.8899 0.9942 221125_WJC_METTL3_EV_vs_WT_F09.03457.03457.2 2.18E-06 22-Nov K.EGNNPAENGDAK[136.11].T sp|P05204|HMGN2_HUMAN 1 1222.5306 1.17 125393 3457 2 1222.522888 612.2726 Non-histone chromosomal protein HMG-17 OS=Homo sapiens OX=9606 GN=HMGN2 PE=1 SV=3 4.14 1307.8 - 2.32E+06 - - - -6.2739 - 1.951 0.543 - 445.8 1 2 0 -0.0077 12 0 0 0 5.36E+07 4.56E+07 - - - 4.8077 0.978 221125_WJC_METTL3_EV_vs_WT_F09.03461.03461.2 0.358 14-Jul K.R[166.11]NSTIPTK[136.11].Q "sp|P0DMV8|HS71A_HUMAN,sp|P34931|HS71L_HUMAN,sp|P0DMV9|HS71B_HUMAN,tr|Q53FA3|Q53FA3_HUMAN,tr|V9GZ37|V9GZ37_HUMAN,tr|A0A0G2JIW1|A0A0G2JIW1_HUMAN" 6 933.5362 0.13 125395 3461 2 933.53432 467.7754 Heat shock 70 kDa protein 1A OS=Homo sapiens OX=9606 GN=HSPA1A PE=1 SV=1 11 1308.4 - 2.22E+06 - - - -2.0674 - 1.548 0.037 - 255 1 2 0 -0.0019 8 0 0 0 4.49E+07 3.33E+08 - - - 0.6315 0.9973 221125_WJC_METTL3_EV_vs_WT_F09.03462.03462.3 0.339 Sep-32 R.TK[136.11]PQMQEER[166.11].R "sp|O75643|U520_HUMAN,tr|A0A494C1A5|A0A494C1A5_HUMAN" 2 1163.5724 1.91 125396 3462 3 1163.569291 388.8647 U5 small nuclear ribonucleoprotein 200 kDa helicase OS=Homo sapiens OX=9606 GN=SNRNP200 PE=1 SV=2 5.81 1308.4 - 2.15E+06 - - - -2.6522 - 1.787 0.275 - 102.9 1 2 0 -0.0031 9 0 0 0 6.93E+07 3.62E+07 - - - 3.3547 0.8887 221125_WJC_METTL3_EV_vs_WT_F09.03463.03463.2 0.0422 16-Jul Q.HEDQVEQYK.K "sp|P02545|LMNA_HUMAN,tr|A0A6Q8PF80|A0A6Q8PF80_HUMAN,tr|A0A804HL68|A0A804HL68_HUMAN,tr|Q5TCI8|Q5TCI8_HUMAN,tr|A0A6Q8PFJ0|A0A6Q8PFJ0_HUMAN,tr|A0A6Q8PHQ9|A0A6Q8PHQ9_HUMAN,tr|Q3BDU5|Q3BDU5_HUMAN" 7 1174.5255 0.88 125397 3463 2 1174.526149 588.27 Prelamin-A\C OS=Homo sapiens OX=9606 GN=LMNA PE=1 SV=1 4.65 1308.5 - 1.05E+06 - - - 0.5807 - 1.221 0.302 - 125.4 1 1 0 0.0007 9 0 0 0 1.89E+07 2.14E+07 - - - 1.849 0.999 221125_WJC_METTL3_EV_vs_WT_F09.03466.03466.2 0.0135 16-Jul R.TKPQMQEER.R "sp|O75643|U520_HUMAN,tr|A0A494C1A5|A0A494C1A5_HUMAN" 2 1145.5499 0.66 125400 3466 2 1145.548189 573.7822 U5 small nuclear ribonucleoprotein 200 kDa helicase OS=Homo sapiens OX=9606 GN=SNRNP200 PE=1 SV=2 5.81 1308.9 - 365174 - - - -1.4997 - 1.336 0.393 - 142.4 1 2 0 -0.0017 9 0 0 0 7.55E+06 1.15E+07 - - - 2.7812 0.9924 221125_WJC_METTL3_EV_vs_WT_F09.03467.03467.2 0.0199 20-Oct R.IVTDR[166.11]ETGSSK[136.11].G "sp|P19338|NUCL_HUMAN,tr|A0A7I2V699|A0A7I2V699_HUMAN,tr|A0A7I2V2U7|A0A7I2V2U7_HUMAN,tr|A0A7I2V3F3|A0A7I2V3F3_HUMAN,tr|A0A7I2V428|A0A7I2V428_HUMAN,tr|H7BY16|H7BY16_HUMAN,tr|A0A7I2V5M5|A0A7I2V5M5_HUMAN,tr|C9JLB1|C9JLB1_HUMAN" 8 1209.632 1.1 125401 3467 2 1209.629665 605.8233 Nucleolin OS=Homo sapiens OX=9606 GN=NCL PE=1 SV=3 6.07 1309 - 206240 - - - -1.9312 - 2.044 0.336 - 276.1 1 2 1 -0.0023 11 0 0 0 4.63E+06 4.22E+06 - - - 3.456 0.9616 221125_WJC_METTL3_EV_vs_WT_F09.03476.03476.3 0.404 13/36 K.VTNVDEEK[136.11]QR[166.11].M "sp|Q14690|RRP5_HUMAN,tr|A0A3B3IUD7|A0A3B3IUD7_HUMAN" 2 1234.6273 2.26 125408 3476 3 1234.621935 412.5497 Protein RRP5 homolog OS=Homo sapiens OX=9606 GN=PDCD11 PE=1 SV=3 4.68 1309.9 - 805915 - - - -4.3049 - 2.191 0.23 - 293.3 1 2 1 -0.0053 10 0 0 0 8.39E+07 3.71E+07 - - - 3.3935 0.9958 221125_WJC_METTL3_EV_vs_WT_F09.03478.03478.2 0.0193 16-Sep R.KLNEQSPTR.C sp|O75396|SC22B_HUMAN 1 1071.5673 2.51 125410 3478 2 1071.563603 536.7909 Vesicle-trafficking protein SEC22b OS=Homo sapiens OX=9606 GN=SEC22B PE=1 SV=5 8.75 1310.1 - 557377 - - - -3.424 - 1.855 0.255 - 333.7 1 2 0 -0.0037 9 0 0 0 1.98E+07 7.91E+06 - - - 2.7109 0.9831 221125_WJC_METTL3_EV_vs_WT_F09.03486.03486.2 5.87 14-Oct K.LK[136.11]EDKLEK[136.11].Q "sp|Q8ND56|LS14A_HUMAN,sp|Q07866|KLC1_HUMAN,tr|G3V5R9|G3V5R9_HUMAN,tr|G3V3H3|G3V3H3_HUMAN,tr|G3V2P7|G3V2P7_HUMAN,tr|F8W6L3|F8W6L3_HUMAN,tr|E7EVH7|E7EVH7_HUMAN,tr|A0A140TA76|A0A140TA76_HUMAN,tr|K7EMZ9|K7EMZ9_HUMAN,tr|G3V2E7|G3V2E7_HUMAN,tr|G5E9S8|G5E9S8_HUMAN" 11 1017.6041 - 125416 3486 2 1017.601827 509.8093 Protein LSM14 homolog A OS=Homo sapiens OX=9606 GN=LSM14A PE=1 SV=3 6.18 1311.1 - 2.19E+06 - - - -2.2445 - 2.225 0.189 - 246.8 1 2 2 -0.0023 8 0 0 0 - - - - - 2.8483 0.8338 221125_WJC_METTL3_EV_vs_WT_F09.03488.03488.3 0.0128 Dec-36 K.VTNVDEEKQR.M "sp|Q14690|RRP5_HUMAN,tr|A0A3B3IUD7|A0A3B3IUD7_HUMAN" 2 1216.6048 2.27 125418 3488 3 1216.597977 406.5422 Protein RRP5 homolog OS=Homo sapiens OX=9606 GN=PDCD11 PE=1 SV=3 4.68 1311.2 - 1.72E+06 - - - -5.5918 - 2.321 0.172 - 293.5 1 2 1 -0.0068 10 0 0 0 8.38E+07 3.69E+07 - - - 2.9148 0.9463 221125_WJC_METTL3_EV_vs_WT_F09.03489.03489.2 0.0642 20-Aug R.IVTDRETGSSK.G "sp|P19338|NUCL_HUMAN,tr|A0A7I2V699|A0A7I2V699_HUMAN,tr|A0A7I2V2U7|A0A7I2V2U7_HUMAN,tr|A0A7I2V3F3|A0A7I2V3F3_HUMAN,tr|A0A7I2V428|A0A7I2V428_HUMAN,tr|H7BY16|H7BY16_HUMAN,tr|A0A7I2V5M5|A0A7I2V5M5_HUMAN,tr|C9JLB1|C9JLB1_HUMAN" 8 1191.6095 1.1 125419 3489 2 1191.60519 596.812 Nucleolin OS=Homo sapiens OX=9606 GN=NCL PE=1 SV=3 6.07 1311.4 - 545089 - - - -3.643 - 1.657 0.309 - 144.9 1 2 1 -0.0043 11 0 0 0 4.63E+06 4.22E+06 - - - 2.6881 0.9983 221125_WJC_METTL3_EV_vs_WT_F09.03490.03490.2 1.44E-05 16-Oct R.VHELEQQNK[136.11].V sp|P07196|NFL_HUMAN 1 1131.5764 1.79 125420 3490 2 1131.571839 566.7955 Neurofilament light polypeptide OS=Homo sapiens OX=9606 GN=NEFL PE=1 SV=3 5.4 1311.5 - 493546 - - - -4.0183 - 1.76 0.481 - 455.6 1 2 0 -0.0045 9 0 0 0 1.56E+07 8.72E+06 - - - 4.2277 1 221125_WJC_METTL3_EV_vs_WT_F09.03494.03494.2 1.26E-06 24-Oct K.LGSSC[160.03]SGSGDSGR.R sp|Q5D862|FILA2_HUMAN 1 1225.4993 118.26 125422 3494 2 1225.495239 613.7569 Filaggrin-2 OS=Homo sapiens OX=9606 GN=FLG2 PE=1 SV=1 5.83 1312 - 2.48E+06 - - - -3.3366 - 2.168 0.639 - 362 1 2 0 -0.0041 13 0 0 0 2.10E+07 1.77E+05 - - - 5.7454 0.7643 221125_WJC_METTL3_EV_vs_WT_F09.03498.03498.3 0.605 Oct-32 R.QNLQEEKER.K sp|Q96CS3|FAF2_HUMAN 1 1172.5786 0.67 125426 3498 3 1172.57666 391.8668 FAS-associated factor 2 OS=Homo sapiens OX=9606 GN=FAF2 PE=1 SV=2 4.79 1312.5 - 766393 - - - -1.6246 - 1.67 0.074 - 165.4 1 2 1 -0.0019 9 0 0 0 6.87E+06 1.03E+07 - - - 0.91 1 221125_WJC_METTL3_EV_vs_WT_F09.03499.03499.2 3.99E-08 22-Dec K.DGADEAESNDGK.V "sp|Q6W2J9|BCOR_HUMAN,tr|H7BZ37|H7BZ37_HUMAN,tr|A1A564|A1A564_HUMAN,tr|H7C2V9|H7C2V9_HUMAN,tr|H7BYY2|H7BYY2_HUMAN,tr|H7C231|H7C231_HUMAN" 6 1206.4637 2.66 125427 3499 2 1206.460465 604.2391 BCL-6 corepressor OS=Homo sapiens OX=9606 GN=BCOR PE=1 SV=1 3.77 1312.6 - 724361 - - - -2.6433 - 2.608 0.693 - 528.7 1 2 0 -0.0032 12 0 0 0 3.31E+07 1.25E+07 - - - 6.6807 0.9903 221125_WJC_METTL3_EV_vs_WT_F09.03506.03506.2 0.00739 20-Oct R.AKEAAEQDVEK.K "sp|P26373|RL13_HUMAN,tr|J3KS98|J3KS98_HUMAN" 2 1216.5935 1.26 125432 3506 2 1216.590866 609.304 60S ribosomal protein L13 OS=Homo sapiens OX=9606 GN=RPL13 PE=1 SV=4 4.41 1313.3 - 1.25E+06 - - - -2.2029 - 2.145 0.311 - 216 1 2 1 -0.0027 11 0 0 0 1.86E+07 1.48E+07 - - - 3.4017 0.9863 221125_WJC_METTL3_EV_vs_WT_F09.03507.03507.2 0.000284 20-Nov R.AK[136.11]EAAEQDVEK[136.11].K "sp|P26373|RL13_HUMAN,tr|J3KS98|J3KS98_HUMAN" 2 1232.6219 1.27 125433 3507 2 1232.61896 617.3182 60S ribosomal protein L13 OS=Homo sapiens OX=9606 GN=RPL13 PE=1 SV=4 4.41 1313.3 - 1.24E+06 - - - -2.4225 - 2.237 0.267 - 257.4 1 2 1 -0.003 11 0 0 0 1.86E+07 1.46E+07 - - - 3.1902 0.9982 221125_WJC_METTL3_EV_vs_WT_F09.03509.03509.2 0.0504 18-Aug K.EEGKPLQQEK.E "sp|P07197|NFM_HUMAN,tr|E7ESP9|E7ESP9_HUMAN" 2 1184.6037 3.14 125435 3509 2 1184.602514 593.3091 Neurofilament medium polypeptide OS=Homo sapiens OX=9606 GN=NEFM PE=1 SV=3 4.79 1313.6 - 333773 - - - -1.0155 - 1.262 0.316 - 148.2 1 2 0 -0.0012 10 0 0 0 6.32E+06 2.01E+06 - - - 2.0241 0.8141 221125_WJC_METTL3_EV_vs_WT_F09.03510.03510.2 4.71 16-May R.ASHPSVTER[166.11].H "sp|Q13724|MOGS_HUMAN,tr|A0A3B3IRK6|A0A3B3IRK6_HUMAN,tr|A0A3B3IRW2|A0A3B3IRW2_HUMAN" 3 992.4915 0.56 125436 3510 2 992.492056 497.253 Mannosyl-oligosaccharide glucosidase OS=Homo sapiens OX=9606 GN=MOGS PE=1 SV=5 6.79 1313.7 - 328161 - - - 0.5824 - 0.887 0.041 - 57.5 4 2 0 0.0006 9 0 0 0 1.74E+06 3.13E+06 - - - -1.2722 0.9999 221125_WJC_METTL3_EV_vs_WT_F09.03513.03513.3 4.38E-06 Dec-44 K.C[160.03]GGAGHIASDC[160.03]K[136.11].F "sp|Q15637|SF01_HUMAN,tr|H7C561|H7C561_HUMAN,tr|A0A7P0T9U7|A0A7P0T9U7_HUMAN" 3 1239.5216 1.23 125437 3513 3 1239.517518 414.1811 Splicing factor 1 OS=Homo sapiens OX=9606 GN=SF1 PE=1 SV=4 6.73 1314.1 - 2.03E+06 - - - -3.2859 - 2.341 0.56 - 187.6 1 2 0 -0.0041 12 0 0 0 2.93E+07 2.37E+07 - - - 7.14 0.9797 221125_WJC_METTL3_EV_vs_WT_F09.03521.03521.2 0.832 14-Aug K.RNSTIPTK.Q "sp|P0DMV8|HS71A_HUMAN,sp|P34931|HS71L_HUMAN,sp|P0DMV9|HS71B_HUMAN,tr|Q53FA3|Q53FA3_HUMAN,tr|V9GZ37|V9GZ37_HUMAN,tr|A0A0G2JIW1|A0A0G2JIW1_HUMAN" 6 915.5138 0.13 125443 3521 2 915.510976 458.7642 Heat shock 70 kDa protein 1A OS=Homo sapiens OX=9606 GN=HSPA1A PE=1 SV=1 11 1315 - 3.48E+06 - - - -3.0628 - 1.65 0.087 - 365.6 1 2 0 -0.0028 8 0 0 0 4.49E+07 3.33E+08 - - - 1.193 0.9935 221125_WJC_METTL3_EV_vs_WT_F09.03535.03535.2 0.784 16-Sep K.NASEDEIK[136.11]K[136.11].A "sp|Q99615|DNJC7_HUMAN,tr|A0A6I8PRZ0|A0A6I8PRZ0_HUMAN,tr|A0A6I8PR89|A0A6I8PR89_HUMAN,tr|A0A6I8PIK4|A0A6I8PIK4_HUMAN,tr|A0A6I8PS32|A0A6I8PS32_HUMAN,tr|A0A6I8PUD4|A0A6I8PUD4_HUMAN,tr|K7EQ73|K7EQ73_HUMAN,tr|K7ER44|K7ER44_HUMAN,tr|A0A6I8PU73|A0A6I8PU73_HUMAN" 9 1048.5372 1.02 125454 3535 2 1048.533907 525.2759 DnaJ homolog subfamily C member 7 OS=Homo sapiens OX=9606 GN=DNAJC7 PE=1 SV=2 4.68 1316.6 - 2.42E+06 - - - -3.0967 - 1.684 0.211 - 300.1 1 2 0 -0.0032 9 0 0 0 3.13E+07 3.08E+07 - - - 2.1062 0.9782 221125_WJC_METTL3_EV_vs_WT_F09.03537.03537.2 0.00617 16-Jul R.ETEDVPKDK.S sp|O43148|MCES_HUMAN 1 1059.5084 0.7 125456 3537 2 1059.505882 530.7615 mRNA cap guanine-N7 methyltransferase OS=Homo sapiens OX=9606 GN=RNMT PE=1 SV=1 4.32 1316.8 - 1.18E+06 - - - -2.3955 - 1.525 0.331 - 201.1 1 2 1 -0.0025 9 0 0 0 1.16E+07 1.66E+07 - - - 2.7058 0.9999 221125_WJC_METTL3_EV_vs_WT_F09.03540.03540.3 0.000643 Oct-32 R.EEYEAHQDR.V sp|Q06587|RING1_HUMAN 1 1175.4843 1.11 125459 3540 3 1175.481487 392.8354 E3 ubiquitin-protein ligase RING1 OS=Homo sapiens OX=9606 GN=RING1 PE=1 SV=2 4.4 1317.2 - 688760 - - - -2.4186 - 1.927 0.482 - 153.7 1 2 0 -0.0028 9 0 0 0 7.13E+06 6.42E+06 - - - 5.89 0.9998 221125_WJC_METTL3_EV_vs_WT_F09.03541.03541.2 8.90E-06 22-Oct K.DSESADAGGAQR[166.11].G "sp|Q9Y5X1|SNX9_HUMAN,tr|A0A7P0T8S8|A0A7P0T8S8_HUMAN,tr|A0A7P0T8D4|A0A7P0T8D4_HUMAN,tr|A0A7P0T8C7|A0A7P0T8C7_HUMAN,tr|A0A7P0Z4A2|A0A7P0Z4A2_HUMAN,tr|A0A7P0T8Z7|A0A7P0T8Z7_HUMAN,tr|A0A7P0T8Z2|A0A7P0T8Z2_HUMAN,tr|A0A7P0Z4A5|A0A7P0Z4A5_HUMAN,tr|A0A7P0TBI9|A0A7P0TBI9_HUMAN" 9 1172.4933 0.78 125460 3541 2 1172.491299 587.2539 Sorting nexin-9 OS=Homo sapiens OX=9606 GN=SNX9 PE=1 SV=1 4.03 1317.3 - 347555 - - - -1.7305 - 2.029 0.532 - 434 1 2 0 -0.002 12 0 0 0 4.28E+06 5.48E+06 - - - 4.8314 1 221125_WJC_METTL3_EV_vs_WT_F09.03546.03546.2 2.12E-09 22-Nov K.DGADEAESNDGK[136.11].V "sp|Q6W2J9|BCOR_HUMAN,tr|H7BZ37|H7BZ37_HUMAN,tr|A1A564|A1A564_HUMAN,tr|H7C2V9|H7C2V9_HUMAN,tr|H7BYY2|H7BYY2_HUMAN,tr|H7C231|H7C231_HUMAN" 6 1214.4779 2.66 125463 3546 2 1214.474644 608.2462 BCL-6 corepressor OS=Homo sapiens OX=9606 GN=BCOR PE=1 SV=1 3.77 1317.9 - 549576 - - - -2.6431 - 2.285 0.748 - 462.9 1 2 0 -0.0032 12 0 0 0 3.31E+07 1.25E+07 - - - 6.739 0.9897 221125_WJC_METTL3_EV_vs_WT_F09.03549.03549.2 0.00674 12-Jul R.SHQDFSR[166.11].Q sp|Q07065|CKAP4_HUMAN 1 885.3968 1.29 125465 3549 2 885.39448 443.7057 Cytoskeleton-associated protein 4 OS=Homo sapiens OX=9606 GN=CKAP4 PE=1 SV=2 6.46 1318.2 - 745608 - - - -2.6756 - 1.327 0.211 - 269 1 2 0 -0.0024 7 0 0 0 7.05E+06 5.48E+06 - - - 1.4952 0.9998 221125_WJC_METTL3_EV_vs_WT_F09.03558.03558.3 0.000151 14/40 K.QATENAK[136.11]EEVR[166.11].R sp|P26641|EF1G_HUMAN 1 1291.6487 1.38 125472 3558 3 1291.646907 431.5568 Elongation factor 1-gamma OS=Homo sapiens OX=9606 GN=EEF1G PE=1 SV=3 4.79 1319.2 - 993398 - - - -1.3982 - 2.554 0.475 - 379.9 1 2 1 -0.0018 11 0 0 0 2.68E+07 1.93E+07 - - - 6.499 0.8341 221125_WJC_METTL3_EV_vs_WT_F09.03559.03559.2 0.138 18-Jun V.NVGAGSHPNK.V "sp|P21333|FLNA_HUMAN,tr|A0A7P0NMY4|A0A7P0NMY4_HUMAN,tr|Q60FE5|Q60FE5_HUMAN" 3 979.4835 12.08 125473 3559 2 979.485356 490.749 Filamin-A OS=Homo sapiens OX=9606 GN=FLNA PE=1 SV=4 8.76 1319.3 - 635273 - - - 1.852 - 1.173 0.339 - 82.8 1 1 0 0.0018 10 0 0 0 3.84E+06 3.17E+05 - - - 1.9897 0.9998 221125_WJC_METTL3_EV_vs_WT_F09.03566.03566.3 7.48E-06 Nov-40 K.QATENAKEEVR.R sp|P26641|EF1G_HUMAN 1 1273.6262 1.3 125478 3566 3 1273.624932 425.5494 Elongation factor 1-gamma OS=Homo sapiens OX=9606 GN=EEF1G PE=1 SV=3 4.79 1320.1 - 2.16E+06 - - - -1.0293 - 2.399 0.476 - 232.5 1 2 1 -0.0013 11 0 0 0 2.52E+07 1.93E+07 - - - 6.3324 1 221125_WJC_METTL3_EV_vs_WT_F09.03569.03569.2 1.40E-07 17/22 R.HVVC[160.03]AAETGSGK[136.11].T sp|Q9NUL7|DDX28_HUMAN 1 1222.5856 0.95 125481 3569 2 1222.586846 612.3001 Probable ATP-dependent RNA helicase DDX28 OS=Homo sapiens OX=9606 GN=DDX28 PE=1 SV=2 6.74 1320.3 - 1.62E+06 - - - 1.0429 - 2.872 0.628 - 821.1 1 2 0 0.0013 12 0 0 0 1.95E+07 2.06E+07 - - - 6.4549 1 221125_WJC_METTL3_EV_vs_WT_F09.03570.03570.2 7.22E-08 17/22 R.HVVC[160.03]AAETGSGK.T sp|Q9NUL7|DDX28_HUMAN 1 1214.5714 0.94 125482 3570 2 1214.568979 608.293 Probable ATP-dependent RNA helicase DDX28 OS=Homo sapiens OX=9606 GN=DDX28 PE=1 SV=2 6.74 1320.4 - 1.48E+06 - - - -1.9694 - 2.836 0.716 - 876.5 1 2 0 -0.0024 12 0 0 0 1.95E+07 2.07E+07 - - - 7.0713 0.9989 221125_WJC_METTL3_EV_vs_WT_F09.03572.03572.2 0.0395 16-Nov K.SQRPEEEVK.S "sp|P82094|TMF1_HUMAN,tr|F8WF45|F8WF45_HUMAN,tr|A0A2R8Y7M0|A0A2R8Y7M0_HUMAN" 3 1100.5462 1.67 125483 3572 2 1100.544496 551.2804 TATA element modulatory factor OS=Homo sapiens OX=9606 GN=TMF1 PE=1 SV=2 4.78 1320.6 - 776236 - - - -1.5501 - 2.007 0.23 - 515.7 1 2 0 -0.0017 9 0 0 0 3.22E+07 1.93E+07 - - - 2.7547 0.9996 221125_WJC_METTL3_EV_vs_WT_F09.03574.03574.2 0.018 22-Aug K.DSESADAGGAQR.G "sp|Q9Y5X1|SNX9_HUMAN,tr|A0A7P0T8S8|A0A7P0T8S8_HUMAN,tr|A0A7P0T8D4|A0A7P0T8D4_HUMAN,tr|A0A7P0T8C7|A0A7P0T8C7_HUMAN,tr|A0A7P0Z4A2|A0A7P0Z4A2_HUMAN,tr|A0A7P0T8Z7|A0A7P0T8Z7_HUMAN,tr|A0A7P0T8Z2|A0A7P0T8Z2_HUMAN,tr|A0A7P0Z4A5|A0A7P0Z4A5_HUMAN,tr|A0A7P0TBI9|A0A7P0TBI9_HUMAN" 9 1162.4851 0.78 125485 3574 2 1162.48322 582.2498 Sorting nexin-9 OS=Homo sapiens OX=9606 GN=SNX9 PE=1 SV=1 4.03 1320.9 - 431169 - - - -1.5811 - 1.757 0.455 - 195.1 1 2 0 -0.0018 12 0 0 0 4.28E+06 5.48E+06 - - - 3.884 0.9967 221125_WJC_METTL3_EV_vs_WT_F09.03578.03578.2 0.000161 20-Oct K.QATENAK[136.11]EEVR[166.11].R sp|P26641|EF1G_HUMAN 1 1291.6487 1.03 125489 3578 2 1291.645961 646.8316 Elongation factor 1-gamma OS=Homo sapiens OX=9606 GN=EEF1G PE=1 SV=3 4.79 1321.4 - 185271 - - - -2.1306 - 2.275 0.476 - 486.5 1 2 1 -0.0028 11 0 0 0 2.11E+06 2.05E+06 - - - 4.7795 0.9985 221125_WJC_METTL3_EV_vs_WT_F09.03582.03582.2 0.0382 16-Sep K.SQR[166.11]PEEEVK[136.11].S "sp|P82094|TMF1_HUMAN,tr|F8WF45|F8WF45_HUMAN,tr|A0A2R8Y7M0|A0A2R8Y7M0_HUMAN" 3 1118.5687 1.67 125491 3582 2 1118.565535 560.2916 TATA element modulatory factor OS=Homo sapiens OX=9606 GN=TMF1 PE=1 SV=2 4.78 1321.9 - 2.80E+06 - - - -2.8045 - 1.977 0.306 - 394.4 1 2 0 -0.0031 9 0 0 0 3.22E+07 1.93E+07 - - - 3.272 0.9999 221125_WJC_METTL3_EV_vs_WT_F09.03583.03583.3 3.92E-07 Nov-44 R.HVVC[160.03]AAETGSGK[136.11].T sp|Q9NUL7|DDX28_HUMAN 1 1222.5856 1.41 125492 3583 3 1222.582376 408.5358 Probable ATP-dependent RNA helicase DDX28 OS=Homo sapiens OX=9606 GN=DDX28 PE=1 SV=2 6.74 1322 - 1.96E+06 - - - -2.6133 - 2.335 0.502 - 284.9 1 2 0 -0.0032 12 0 0 0 1.45E+07 1.03E+07 - - - 6.4865 0.9214 221125_WJC_METTL3_EV_vs_WT_F09.03592.03592.2 0.0175 16-Oct T.R[166.11]SVSSSSYR[166.11].R "sp|P08670|VIME_HUMAN,tr|B0YJC4|B0YJC4_HUMAN,tr|A0A1B0GVG8|A0A1B0GVG8_HUMAN,tr|A0A1B0GTT5|A0A1B0GTT5_HUMAN" 4 1047.5212 -1 125501 3592 2 1047.518208 524.7679 Vimentin OS=Homo sapiens OX=9606 GN=VIM PE=1 SV=4 10.84 1323 - 654155 - - - -2.8668 - 1.782 0.364 - 132.8 1 1 0 -0.003 9 0 0 0 0.00E+00 0.00E+00 - - - 3.4 0.9985 221125_WJC_METTL3_EV_vs_WT_F09.03594.03594.2 0.0256 14-Jul R.NTTIPTKK.S "sp|P38646|GRP75_HUMAN,tr|A0A7I2V2S7|A0A7I2V2S7_HUMAN,tr|A0A7I2V2G2|A0A7I2V2G2_HUMAN,tr|A0A7I2YQB2|A0A7I2YQB2_HUMAN,tr|D6RCD7|D6RCD7_HUMAN" 5 901.5233 0.42 125503 3594 2 901.521584 451.7689 "Stress-70 protein, mitochondrial OS=Homo sapiens OX=9606 GN=HSPA9 PE=1 SV=2" 10 1323.3 - 628204 - - - -1.8835 - 1.479 0.323 - 252.7 1 2 0 -0.0017 8 0 0 0 2.87E+07 6.76E+07 - - - 2.6065 0.9837 221125_WJC_METTL3_EV_vs_WT_F09.03607.03607.2 0.0543 14-Jul R.EKEEQLQR.Q "sp|Q14244|MAP7_HUMAN,tr|A0A087WZ40|A0A087WZ40_HUMAN" 2 1058.5356 1.35 125515 3607 2 1058.533731 530.2751 Ensconsin OS=Homo sapiens OX=9606 GN=MAP7 PE=1 SV=1 4.79 1324.4 - 494123 - - - -1.8006 - 1.612 0.285 - 182.7 1 2 1 -0.0019 8 0 0 0 9.85E+06 7.32E+06 - - - 2.5855 0.9794 221125_WJC_METTL3_EV_vs_WT_F09.03611.03611.2 0.000357 18-Oct F.GSDQSENVDR.G "sp|Q9UII2|ATIF1_HUMAN,tr|A0A0B4J230|A0A0B4J230_HUMAN" 2 1105.4636 0.9 125517 3611 2 1105.46071 553.7391 "ATPase inhibitor, mitochondrial OS=Homo sapiens OX=9606 GN=ATP5IF1 PE=1 SV=1" 4.03 1325 - 2.12E+06 - - - -2.6098 - 2.188 0.53 - 488.5 1 1 0 -0.0029 10 0 0 0 1.60E+07 1.78E+07 - - - 5.1402 0.9785 221125_WJC_METTL3_EV_vs_WT_F09.03612.03612.2 0.000397 18-Sep F.GSDQSENVDR[166.11].G "sp|Q9UII2|ATIF1_HUMAN,tr|A0A0B4J230|A0A0B4J230_HUMAN" 2 1115.4719 0.91 125518 3612 2 1115.469196 558.7432 "ATPase inhibitor, mitochondrial OS=Homo sapiens OX=9606 GN=ATP5IF1 PE=1 SV=1" 4.03 1325 - 1.91E+06 - - - -2.3927 - 2.13 0.488 - 335.1 1 1 0 -0.0027 10 0 0 0 1.60E+07 1.77E+07 - - - 4.7551 0.9946 221125_WJC_METTL3_EV_vs_WT_F09.03619.03619.3 0.00131 Aug-36 K.EHEQTDSEIK[136.11].Q "sp|Q15643|TRIPB_HUMAN,tr|H0YJ97|H0YJ97_HUMAN" 2 1222.5557 1.14 125523 3619 3 1222.549649 408.5258 Thyroid receptor-interacting protein 11 OS=Homo sapiens OX=9606 GN=TRIP11 PE=1 SV=3 4.4 1325.9 - 1.80E+06 - - - -4.9585 - 1.716 0.358 - 151.6 1 2 0 -0.0061 10 0 0 0 4.31E+07 3.78E+07 - - - 4.1067 1 221125_WJC_METTL3_EV_vs_WT_F09.03622.03622.2 1.68E-06 14/26 R.GGGGGGLGNNGSSR[166.11].G sp|Q96DT7|ZBT10_HUMAN 1 1155.5256 0.64 125526 3622 2 1155.521652 578.7701 Zinc finger and BTB domain-containing protein 10 OS=Homo sapiens OX=9606 GN=ZBTB10 PE=1 SV=2 9.75 1326.2 - 407282 - - - -3.4435 - 3.031 0.537 - 487.1 1 2 0 -0.004 14 0 0 0 3.27E+06 5.08E+06 - - - 5.7887 0.9997 221125_WJC_METTL3_EV_vs_WT_F09.03633.03633.2 0.000689 22-Aug K.GESSSPSPSAEK.G "sp|P28290|ITPI2_HUMAN,tr|E9PHV5|E9PHV5_HUMAN" 2 1161.515 2.54 125535 3633 2 1161.516386 581.7648 Protein ITPRID2 OS=Homo sapiens OX=9606 GN=ITPRID2 PE=1 SV=3 4.53 1327.6 - 164941 - - - 1.2268 - 1.703 0.504 - 193 1 2 0 0.0014 12 0 0 0 2.66E+06 1.05E+06 - - - 4.1639 0.9995 221125_WJC_METTL3_EV_vs_WT_F09.03636.03636.3 0.00208 Sep-36 K.EHEQTDSEIK.Q "sp|Q15643|TRIPB_HUMAN,tr|H0YJ97|H0YJ97_HUMAN" 2 1214.5415 1.16 125536 3636 3 1214.537646 405.8544 Thyroid receptor-interacting protein 11 OS=Homo sapiens OX=9606 GN=TRIP11 PE=1 SV=3 4.4 1328 - 5.99E+06 - - - -3.1823 - 1.718 0.444 - 194.6 1 2 0 -0.0039 10 0 0 0 4.29E+07 3.70E+07 - - - 5.0695 0.9989 221125_WJC_METTL3_EV_vs_WT_F09.03638.03638.3 1.74E-05 15/44 K.AALGDSKEDTQK.A "sp|Q9NRA8|4ET_HUMAN,tr|B1AKL4|B1AKL4_HUMAN" 2 1261.615 1.07 125538 3638 3 1261.611673 421.5456 Eukaryotic translation initiation factor 4E transporter OS=Homo sapiens OX=9606 GN=EIF4ENIF1 PE=1 SV=2 4.56 1328.2 - 2.20E+06 - - - -2.645 - 2.798 0.359 - 373.1 1 2 1 -0.0033 12 0 0 0 1.39E+08 1.31E+08 - - - 5.3935 0.9996 221125_WJC_METTL3_EV_vs_WT_F09.03639.03639.2 0.000401 18-Dec K.EHEQTDSEIK.Q "sp|Q15643|TRIPB_HUMAN,tr|H0YJ97|H0YJ97_HUMAN" 2 1214.5415 0.35 125539 3639 2 1214.538453 608.278 Thyroid receptor-interacting protein 11 OS=Homo sapiens OX=9606 GN=TRIP11 PE=1 SV=3 4.4 1328.3 - 1.21E+06 - - - -2.5178 - 2.32 0.435 - 592.1 1 2 0 -0.0031 10 0 0 0 9.56E+06 2.76E+07 - - - 4.602 0.9986 221125_WJC_METTL3_EV_vs_WT_F09.03642.03642.2 0.000266 14-Jul R.DC[160.03]QLNAHK[136.11].D "sp|Q13263|TIF1B_HUMAN,tr|M0R2I3|M0R2I3_HUMAN,tr|M0R3C0|M0R3C0_HUMAN" 3 992.4589 0.83 125542 3642 2 992.45566 497.2367 Transcription intermediary factor 1-beta OS=Homo sapiens OX=9606 GN=TRIM28 PE=1 SV=5 6.73 1328.6 - 683169 - - - -3.2787 - 1.484 0.476 - 219.3 1 2 0 -0.0033 8 0 0 0 4.26E+06 5.12E+06 - - - 3.7462 0.9979 221125_WJC_METTL3_EV_vs_WT_F09.03644.03644.2 0.00258 14-Aug R.DC[160.03]QLNAHK.D "sp|Q13263|TIF1B_HUMAN,tr|M0R2I3|M0R2I3_HUMAN,tr|M0R3C0|M0R3C0_HUMAN" 3 984.4447 0.83 125543 3644 2 984.441107 493.2296 Transcription intermediary factor 1-beta OS=Homo sapiens OX=9606 GN=TRIM28 PE=1 SV=5 6.73 1328.8 - 543269 - - - -3.664 - 1.38 0.485 - 260.6 1 2 0 -0.0036 8 0 0 0 4.26E+06 5.12E+06 - - - 3.5935 0.9997 221125_WJC_METTL3_EV_vs_WT_F09.03646.03646.3 0.286 13/44 K.AALGDSK[136.11]EDTQK[136.11].A "sp|Q9NRA8|4ET_HUMAN,tr|B1AKL4|B1AKL4_HUMAN" 2 1277.6434 1.04 125544 3646 3 1277.641044 426.8884 Eukaryotic translation initiation factor 4E transporter OS=Homo sapiens OX=9606 GN=EIF4ENIF1 PE=1 SV=2 4.56 1329.1 - 7.30E+06 - - - -1.8518 - 2.696 0.44 - 253.6 1 2 1 -0.0024 12 0 0 0 1.40E+08 1.34E+08 - - - 6.1939 0.999 221125_WJC_METTL3_EV_vs_WT_F09.03648.03648.3 0.0155 13/36 K.LPQTSDDEKK.D sp|Q9GZT3|SLIRP_HUMAN 1 1159.5721 1.18 125546 3648 3 1159.569291 387.5313 "SRA stem-loop-interacting RNA-binding protein, mitochondrial OS=Homo sapiens OX=9606 GN=SLIRP PE=1 SV=1" 4.56 1329.2 - 3.17E+06 - - - -2.4069 - 1.929 0.314 - 208.5 1 2 0 -0.0028 10 0 0 0 2.79E+07 2.37E+07 - - - 3.9587 1 221125_WJC_METTL3_EV_vs_WT_F09.03651.03651.2 3.90E-09 16/22 K.AALGDSKEDTQK.A "sp|Q9NRA8|4ET_HUMAN,tr|B1AKL4|B1AKL4_HUMAN" 2 1261.615 1.07 125549 3651 2 1261.612539 631.8148 Eukaryotic translation initiation factor 4E transporter OS=Homo sapiens OX=9606 GN=EIF4ENIF1 PE=1 SV=2 4.56 1329.4 - 913963 - - - -1.9586 - 2.94 0.621 - 1164.8 1 2 1 -0.0025 12 0 0 0 1.92E+07 1.80E+07 - - - 6.4644 1 221125_WJC_METTL3_EV_vs_WT_F09.03652.03652.2 0.00455 17/22 K.AALGDSK[136.11]EDTQK[136.11].A "sp|Q9NRA8|4ET_HUMAN,tr|B1AKL4|B1AKL4_HUMAN" 2 1277.6434 1.07 125550 3652 2 1277.640035 639.829 Eukaryotic translation initiation factor 4E transporter OS=Homo sapiens OX=9606 GN=EIF4ENIF1 PE=1 SV=2 4.56 1329.6 - 760940 - - - -2.6416 - 3.034 0.534 - 1234.7 1 2 1 -0.0034 12 0 0 0 1.92E+07 1.80E+07 - - - 5.9044 0.9999 221125_WJC_METTL3_EV_vs_WT_F09.03659.03659.3 9.62E-05 Nov-36 K.IGK[136.11]PHTVPC[160.03]K[136.11].V "sp|P15880|RS2_HUMAN,tr|I3L404|I3L404_HUMAN,tr|E9PM36|E9PM36_HUMAN,tr|E9PPT0|E9PPT0_HUMAN,tr|E9PMM9|E9PMM9_HUMAN,tr|H0YEN5|H0YEN5_HUMAN" 6 1151.6456 0.03 125555 3659 3 1151.643178 384.8891 40S ribosomal protein S2 OS=Homo sapiens OX=9606 GN=RPS2 PE=1 SV=2 9.31 1330.5 - 2.84E+06 - - - -2.1022 - 2.252 0.415 - 141.8 1 2 0 -0.0024 10 0 0 0 2.04E+06 7.23E+07 - - - 5.537 0.8483 221125_WJC_METTL3_EV_vs_WT_F09.03662.03662.2 0.000271 14/18 A.LGDSKEDTQK.A "sp|Q9NRA8|4ET_HUMAN,tr|B1AKL4|B1AKL4_HUMAN" 2 1119.5408 1.29 125558 3662 2 1119.540917 560.7777 Eukaryotic translation initiation factor 4E transporter OS=Homo sapiens OX=9606 GN=EIF4ENIF1 PE=1 SV=2 4.56 1330.9 - 919590 - - - 0.1206 - 2.746 0.253 - 678.5 1 1 1 0.0001 10 0 0 0 6.33E+06 4.91E+06 - - - 3.7292 0.9996 221125_WJC_METTL3_EV_vs_WT_F09.03665.03665.2 0.000648 18-Jun K.LPQTSDDEK[136.11]K[136.11].D sp|Q9GZT3|SLIRP_HUMAN 1 1175.6005 1.08 125561 3665 2 1175.599307 588.8075 "SRA stem-loop-interacting RNA-binding protein, mitochondrial OS=Homo sapiens OX=9606 GN=SLIRP PE=1 SV=1" 4.56 1331.2 - 264667 - - - -0.9995 - 1.456 0.471 - 131.4 1 2 0 -0.0012 10 0 0 0 2.49E+06 2.32E+06 - - - 3.5681 0.9995 221125_WJC_METTL3_EV_vs_WT_F09.03671.03671.3 0.00142 Dec-36 R.IRDVTNNQEK.H "sp|Q9Y2L1|RRP44_HUMAN,tr|F2Z2C0|F2Z2C0_HUMAN" 2 1215.6208 1.69 125565 3671 3 1215.618101 406.2142 Exosome complex exonuclease RRP44 OS=Homo sapiens OX=9606 GN=DIS3 PE=1 SV=2 6.07 1332 - 6.99E+06 - - - -2.1907 - 2.375 0.421 - 291.6 1 2 1 -0.0027 10 0 0 0 1.50E+08 8.92E+07 - - - 5.7592 0.9999 221125_WJC_METTL3_EV_vs_WT_F09.03672.03672.2 1.04E-06 20-Dec R.TGSQGQC[160.03]TQVR[166.11].V sp|P62857|RS28_HUMAN 1 1230.5651 0.93 125566 3672 2 1230.563105 616.2898 40S ribosomal protein S28 OS=Homo sapiens OX=9606 GN=RPS28 PE=1 SV=1 7.91 1332.1 - 4.94E+06 - - - -1.5838 - 2.638 0.523 - 559 1 2 0 -0.0019 11 0 0 0 4.99E+08 5.37E+08 - - - 5.5274 1 221125_WJC_METTL3_EV_vs_WT_F09.03673.03673.2 3.44E-07 13/20 R.TGSQGQC[160.03]TQVR.V sp|P62857|RS28_HUMAN 1 1220.5568 0.93 125567 3673 2 1220.555326 611.2857 40S ribosomal protein S28 OS=Homo sapiens OX=9606 GN=RPS28 PE=1 SV=1 7.91 1332.2 - 2.93E+06 - - - -1.1945 - 2.933 0.618 - 729 1 2 0 -0.0015 11 0 0 0 4.99E+08 5.37E+08 - - - 6.516 1 221125_WJC_METTL3_EV_vs_WT_F09.03675.03675.2 0.000148 14/26 R.GSGGGSSGGSIGGR.G sp|P04264|K2C1_HUMAN 1 1091.4956 999 125569 3675 2 1091.493471 546.7551 "Keratin, type II cytoskeletal 1 OS=Homo sapiens OX=9606 GN=KRT1 PE=1 SV=6" 9.75 1332.3 - 2.53E+06 - - - -1.9166 - 2.978 0.539 - 543 1 2 0 -0.0021 14 0 0 0 3.22E+10 0.00E+00 - - - 5.7598 0.9973 221125_WJC_METTL3_EV_vs_WT_F09.03676.03676.2 0.000163 13/18 R.IRDVTNNQEK.H "sp|Q9Y2L1|RRP44_HUMAN,tr|F2Z2C0|F2Z2C0_HUMAN" 2 1215.6208 1.93 125570 3676 2 1215.618692 608.8177 Exosome complex exonuclease RRP44 OS=Homo sapiens OX=9606 GN=DIS3 PE=1 SV=2 6.07 1332.4 - 1.33E+06 - - - -1.7045 - 2.495 0.417 - 518.8 1 2 1 -0.0021 10 0 0 0 3.96E+07 2.05E+07 - - - 4.6724 0.9995 221125_WJC_METTL3_EV_vs_WT_F09.03680.03680.3 0.00132 Oct-36 K.K[136.11]PSQTASYER[166.11].L sp|Q8WUF5|IASPP_HUMAN 1 1183.5952 28.33 125574 3680 3 1183.592943 395.539 RelA-associated inhibitor OS=Homo sapiens OX=9606 GN=PPP1R13L PE=1 SV=4 8.59 1332.8 - 510713 - - - -1.9246 - 2.013 0.334 - 224.8 1 2 0 -0.0023 10 0 0 0 1.39E+08 4.92E+06 - - - 4.3064 0.9787 221125_WJC_METTL3_EV_vs_WT_F09.03682.03682.2 0.000394 16-Aug L.GK[136.11]PHTVPC[160.03]K[136.11].V "sp|P15880|RS2_HUMAN,tr|I3L404|I3L404_HUMAN,tr|E9PM36|E9PM36_HUMAN,tr|E9PMM9|E9PMM9_HUMAN,tr|H0YEN5|H0YEN5_HUMAN" 5 1038.5615 1.12 125576 3682 2 1038.562456 520.288 40S ribosomal protein S2 OS=Homo sapiens OX=9606 GN=RPS2 PE=1 SV=2 9.31 1333 - 341764 - - - 0.8868 - 1.502 0.461 - 219.2 1 1 0 0.0009 9 0 0 0 2.81E+06 2.52E+06 - - - 3.6225 0.9985 221125_WJC_METTL3_EV_vs_WT_F09.03683.03683.2 0.00914 18-Jul K.KPSQTASYER.L sp|Q8WUF5|IASPP_HUMAN 1 1165.5728 3.15 125577 3683 2 1165.570767 583.7937 RelA-associated inhibitor OS=Homo sapiens OX=9606 GN=PPP1R13L PE=1 SV=4 8.59 1333.2 - 285665 - - - -1.7022 - 1.645 0.285 - 157.5 1 2 0 -0.002 10 0 0 0 3.54E+06 1.12E+06 - - - 2.5347 0.8622 221125_WJC_METTL3_EV_vs_WT_F09.03684.03684.2 0.743 18-May K.LPQTSDDEKK.D sp|Q9GZT3|SLIRP_HUMAN 1 1159.5721 1.08 125578 3684 2 1159.56825 580.7933 "SRA stem-loop-interacting RNA-binding protein, mitochondrial OS=Homo sapiens OX=9606 GN=SLIRP PE=1 SV=1" 4.56 1333.3 - 256636 - - - -3.3047 - 0.991 0.126 - 97.9 1 2 0 -0.0038 10 0 0 0 2.49E+06 2.32E+06 - - - -0.0548 0.9996 221125_WJC_METTL3_EV_vs_WT_F09.03686.03686.2 0.000268 18-Oct K.SAVGHEYQSK[136.11].L sp|Q14247|SRC8_HUMAN 1 1112.5342 -1 125580 3686 2 1112.53189 557.2744 Src substrate cortactin OS=Homo sapiens OX=9606 GN=CTTN PE=1 SV=2 6.47 1333.6 - 161791 - - - -2.0647 - 1.975 0.431 - 450.5 1 2 0 -0.0023 10 0 0 0 0.00E+00 0.00E+00 - - - 4.1233 0.9951 221125_WJC_METTL3_EV_vs_WT_F09.03707.03707.2 0.00599 18-Jun K.K[136.11]PSQTASYER[166.11].L sp|Q8WUF5|IASPP_HUMAN 1 1183.5952 3.71 125599 3707 2 1183.59043 592.8049 RelA-associated inhibitor OS=Homo sapiens OX=9606 GN=PPP1R13L PE=1 SV=4 8.59 1336 - 171565 - - - -4.0478 - 1.489 0.385 - 107.7 1 2 0 -0.0048 10 0 0 0 4.17E+06 1.12E+06 - - - 2.9943 0.9955 221125_WJC_METTL3_EV_vs_WT_F09.03726.03726.2 0.407 16-Aug K.HSLSGRPLK.V "sp|P52272|HNRPM_HUMAN,tr|M0R019|M0R019_HUMAN,tr|M0R0N3|M0R0N3_HUMAN,tr|A0A087X0X3|A0A087X0X3_HUMAN,tr|M0QYQ7|M0QYQ7_HUMAN,tr|M0R2T0|M0R2T0_HUMAN" 6 993.572 1.63 125611 3726 2 993.569414 497.7933 Heterogeneous nuclear ribonucleoprotein M OS=Homo sapiens OX=9606 GN=HNRNPM PE=1 SV=3 11 1338.1 - 3.29E+06 - - - -2.5655 - 1.529 0.246 - 118.6 1 2 0 -0.0025 9 0 0 0 1.36E+08 8.32E+07 - - - 2.0856 0.8445 221125_WJC_METTL3_EV_vs_WT_F09.03730.03730.2 0.0824 12-Jul K.QHSLLKR.L "sp|P62841|RS15_HUMAN,tr|K7EJ78|K7EJ78_HUMAN,tr|K7EM56|K7EM56_HUMAN,tr|A0A0B4J2B4|A0A0B4J2B4_HUMAN,tr|S4R456|S4R456_HUMAN,tr|K7ELC2|K7ELC2_HUMAN,tr|K7EQJ5|K7EQJ5_HUMAN,tr|S4R417|S4R417_HUMAN" 8 880.5243 1.17 125614 3730 2 880.520469 441.2694 40S ribosomal protein S15 OS=Homo sapiens OX=9606 GN=RPS15 PE=1 SV=2 11 1338.6 - 1.45E+06 - - - -4.3338 - 1.319 0.057 - 317.5 1 2 0 -0.0038 7 0 0 0 1.26E+07 1.07E+07 - - - 0.3381 0.999 221125_WJC_METTL3_EV_vs_WT_F09.03731.03731.2 0.0571 16-Nov K.QSTIVC[160.03]HNR[166.11].V "sp|Q16531|DDB1_HUMAN,tr|F5GWI0|F5GWI0_HUMAN,tr|A0A7P0TAK7|A0A7P0TAK7_HUMAN,tr|A0A7P0T870|A0A7P0T870_HUMAN,tr|A0A7P0TB30|A0A7P0TB30_HUMAN,tr|A0A7P0Z3Z5|A0A7P0Z3Z5_HUMAN,tr|F5GY55|F5GY55_HUMAN,tr|A0A7P0Z4B9|A0A7P0Z4B9_HUMAN,tr|A0A7P0T965|A0A7P0T965_HUMAN" 9 1123.5432 1.22 125615 3731 2 1123.539378 562.7789 DNA damage-binding protein 1 OS=Homo sapiens OX=9606 GN=DDB1 PE=1 SV=1 8.26 1338.7 - 1.06E+06 - - - -3.3982 - 2.367 0.373 - 694.5 1 2 0 -0.0038 9 0 0 0 7.56E+06 6.20E+06 - - - 4.2875 0.9696 221125_WJC_METTL3_EV_vs_WT_F09.03734.03734.3 0.0361 Sep-36 R.EALQEK[136.11]EEQK[136.11].T "sp|Q13435|SF3B2_HUMAN,tr|E9PPJ0|E9PPJ0_HUMAN" 2 1246.6376 1.27 125616 3734 3 1246.632498 416.5531 Splicing factor 3B subunit 2 OS=Homo sapiens OX=9606 GN=SF3B2 PE=1 SV=2 4.49 1339.1 - 9.32E+06 - - - -4.0894 - 1.913 0.271 - 110.3 1 2 1 -0.0051 10 0 0 0 2.90E+08 2.28E+08 - - - 3.4544 0.9495 221125_WJC_METTL3_EV_vs_WT_F09.03735.03735.2 0.0009 22-Dec S.GGGSSGGSIGGR.G sp|P04264|K2C1_HUMAN 1 947.4421 352.46 125617 3735 2 947.439515 474.7283 "Keratin, type II cytoskeletal 1 OS=Homo sapiens OX=9606 GN=KRT1 PE=1 SV=6" 9.75 1339.2 - 3.16E+06 - - - -2.6978 - 2.693 0.293 - 594.8 1 1 0 -0.0026 12 0 0 0 5.22E+07 1.48E+05 - - - 3.8109 0.998 221125_WJC_METTL3_EV_vs_WT_F09.03736.03736.2 0.0553 16-Nov K.HSLSGR[166.11]PLK[136.11].V "sp|P52272|HNRPM_HUMAN,tr|M0R019|M0R019_HUMAN,tr|M0R0N3|M0R0N3_HUMAN,tr|A0A087X0X3|A0A087X0X3_HUMAN,tr|M0QYQ7|M0QYQ7_HUMAN,tr|M0R2T0|M0R2T0_HUMAN" 6 1011.5944 1.63 125618 3736 2 1011.591125 506.8045 Heterogeneous nuclear ribonucleoprotein M OS=Homo sapiens OX=9606 GN=HNRNPM PE=1 SV=3 11 1339.3 - 3.40E+06 - - - -3.2701 - 1.806 0.351 - 246.6 1 2 0 -0.0033 9 0 0 0 1.36E+08 8.32E+07 - - - 3.3426 0.998 221125_WJC_METTL3_EV_vs_WT_F09.03739.03739.2 8.91E-05 14/18 K.K[136.11]GDSSAEELK[136.11].L sp|P26373|RL13_HUMAN 1 1078.5477 1.23 125619 3739 2 1078.542867 540.2811 60S ribosomal protein L13 OS=Homo sapiens OX=9606 GN=RPL13 PE=1 SV=4 4.68 1339.6 - 3.16E+06 - - - -4.4986 - 2.764 0.352 - 601.2 1 2 0 -0.0049 10 0 0 0 8.43E+07 6.84E+07 - - - 4.4772 0.986 221125_WJC_METTL3_EV_vs_WT_F09.03741.03741.2 0.00101 13/18 R.EALQEK[136.11]EEQK[136.11].T "sp|Q13435|SF3B2_HUMAN,tr|E9PPJ0|E9PPJ0_HUMAN" 2 1246.6376 1.21 125620 3741 2 1246.632671 624.3261 Splicing factor 3B subunit 2 OS=Homo sapiens OX=9606 GN=SF3B2 PE=1 SV=2 4.49 1339.9 - 3.78E+06 - - - -3.9506 - 2.327 0.433 - 704.2 1 2 1 -0.0049 10 0 0 0 7.61E+07 6.31E+07 - - - 4.5951 0.9986 221125_WJC_METTL3_EV_vs_WT_F09.03743.03743.2 0.0025 13/18 K.KGDSSAEELK.L sp|P26373|RL13_HUMAN 1 1062.5193 1.23 125621 3743 2 1062.514983 532.2669 60S ribosomal protein L13 OS=Homo sapiens OX=9606 GN=RPL13 PE=1 SV=4 4.68 1340.1 - 4.71E+06 - - - -4.0809 - 2.755 0.367 - 517.8 1 2 0 -0.0043 10 0 0 0 8.43E+07 6.84E+07 - - - 4.5791 0.9898 221125_WJC_METTL3_EV_vs_WT_F09.03746.03746.2 0.00157 18-Nov R.EALQEKEEQK.T "sp|Q13435|SF3B2_HUMAN,tr|E9PPJ0|E9PPJ0_HUMAN" 2 1230.6092 1.21 125622 3746 2 1230.606173 616.3119 Splicing factor 3B subunit 2 OS=Homo sapiens OX=9606 GN=SF3B2 PE=1 SV=2 4.49 1340.4 - 4.04E+06 - - - -2.4565 - 1.98 0.352 - 526.3 1 2 1 -0.003 10 0 0 0 7.61E+07 6.31E+07 - - - 3.5467 0.9979 221125_WJC_METTL3_EV_vs_WT_F09.03748.03748.3 0.000206 Nov-40 K.AAEEPSKVEEK.K sp|P29966|MARCS_HUMAN 1 1215.5983 0.55 125623 3748 3 1215.592767 406.2067 Myristoylated alanine-rich C-kinase substrate OS=Homo sapiens OX=9606 GN=MARCKS PE=1 SV=4 4.49 1340.7 - 6.90E+06 - - - -4.5492 - 2.308 0.473 - 207.6 1 2 1 -0.0055 11 0 0 0 1.24E+08 2.27E+08 - - - 6.188 0.9983 221125_WJC_METTL3_EV_vs_WT_F09.03751.03751.3 0.00213 14/32 R.QQQQEALR[166.11]R[166.11].L "sp|Q6Y7W6|GGYF2_HUMAN,tr|A0A7I2V3H7|A0A7I2V3H7_HUMAN,tr|I1E4Y6|I1E4Y6_HUMAN,tr|A0A7I2V516|A0A7I2V516_HUMAN,tr|A0A7I2V3H0|A0A7I2V3H0_HUMAN,tr|A0A7I2V361|A0A7I2V361_HUMAN" 6 1175.6274 2.53 125625 3751 3 1175.622139 392.8831 GRB10-interacting GYF protein 2 OS=Homo sapiens OX=9606 GN=GIGYF2 PE=1 SV=1 9.6 1341 - 2.74E+06 - - - -4.4819 - 2.17 0.351 - 383.8 1 2 0 -0.0053 9 0 0 0 3.26E+08 1.29E+08 - - - 4.7867 0.9285 221125_WJC_METTL3_EV_vs_WT_F09.03762.03762.2 0.7 16-Aug R.QQQQEALRR.L "sp|Q6Y7W6|GGYF2_HUMAN,tr|A0A7I2V3H7|A0A7I2V3H7_HUMAN,tr|I1E4Y6|I1E4Y6_HUMAN,tr|A0A7I2V516|A0A7I2V516_HUMAN,tr|A0A7I2V3H0|A0A7I2V3H0_HUMAN,tr|A0A7I2V361|A0A7I2V361_HUMAN" 6 1155.6109 2.92 125631 3762 2 1155.606509 578.8127 GRB10-interacting GYF protein 2 OS=Homo sapiens OX=9606 GN=GIGYF2 PE=1 SV=1 9.6 1342.1 - 1.29E+06 - - - -3.772 - 1.445 0.073 - 124.3 1 2 0 -0.0044 9 0 0 0 3.01E+07 1.03E+07 - - - 0.6438 0.9933 221125_WJC_METTL3_EV_vs_WT_F09.03764.03764.2 0.0834 14-Jun K.FVEEQHTK.K sp|Q96A49|SYAP1_HUMAN 1 1016.4927 1.75 125633 3764 2 1016.489405 509.2536 Synapse-associated protein 1 OS=Homo sapiens OX=9606 GN=SYAP1 PE=1 SV=1 5.4 1342.3 - 331908 - - - -3.2514 - 1.138 0.372 - 91.8 1 2 0 -0.0033 8 0 0 0 3.86E+06 2.21E+06 - - - 2.1774 0.9841 221125_WJC_METTL3_EV_vs_WT_F09.03769.03769.3 0.0163 Oct-44 R.LKQSAEEQAQAR.A sp|Q15149|PLEC_HUMAN 1 1357.695 1.81 125636 3769 3 1357.689356 453.5723 Plectin OS=Homo sapiens OX=9606 GN=PLEC PE=1 SV=3 6.14 1342.9 - 747050 - - - -4.1512 - 2.104 0.304 - 135 1 2 1 -0.0056 12 0 0 0 8.54E+06 4.73E+06 - - - 3.9896 0.9953 221125_WJC_METTL3_EV_vs_WT_F09.03771.03771.2 0.00816 16-Aug R.K[136.11]VQENSIQR[166.11].V "sp|Q96IZ6|MET2A_HUMAN,sp|Q6P1Q9|MET2B_HUMAN,tr|F8WAS9|F8WAS9_HUMAN" 3 1118.6163 0.61 125638 3771 2 1118.614143 560.3154 tRNA N(3)-methylcytidine methyltransferase METTL2A OS=Homo sapiens OX=9606 GN=METTL2A PE=1 SV=5 8.75 1343.2 - 262024 - - - -1.9202 - 1.638 0.165 - 245.7 1 2 0 -0.0021 9 0 0 0 2.39E+06 3.91E+06 - - - 1.6867 0.7653 221125_WJC_METTL3_EV_vs_WT_F09.03774.03774.3 0.199 Nov-32 R.QQQQEALRR.L "sp|Q6Y7W6|GGYF2_HUMAN,tr|A0A7I2V3H7|A0A7I2V3H7_HUMAN,tr|I1E4Y6|I1E4Y6_HUMAN,tr|A0A7I2V516|A0A7I2V516_HUMAN,tr|A0A7I2V3H0|A0A7I2V3H0_HUMAN,tr|A0A7I2V361|A0A7I2V361_HUMAN" 6 1155.6109 2.53 125639 3774 3 1155.608482 386.2109 GRB10-interacting GYF protein 2 OS=Homo sapiens OX=9606 GN=GIGYF2 PE=1 SV=1 9.6 1343.6 - 2.70E+07 - - - -2.0647 - 1.616 0.023 - 239.2 1 2 0 -0.0024 9 0 0 0 3.26E+08 1.29E+08 - - - 0.2423 0.9999 221125_WJC_METTL3_EV_vs_WT_F09.03780.03780.3 2.76E-07 13/36 R.K[136.11]DSETGENIR[166.11].Q "sp|P38646|GRP75_HUMAN,tr|A0A7I2V2S7|A0A7I2V2S7_HUMAN,tr|A0A7I2V2G2|A0A7I2V2G2_HUMAN,tr|A0A7I2V3F7|A0A7I2V3F7_HUMAN,tr|A0A7I2YQB2|A0A7I2YQB2_HUMAN,tr|D6RCD7|D6RCD7_HUMAN" 6 1165.5694 0.48 125643 3780 3 1165.566558 389.5304 "Stress-70 protein, mitochondrial OS=Homo sapiens OX=9606 GN=HSPA9 PE=1 SV=2" 4.68 1344.3 - 4.05E+06 - - - -2.4383 - 2.436 0.517 - 444.2 1 2 0 -0.0028 10 0 0 0 9.26E+07 1.94E+08 - - - 6.9035 0.9993 221125_WJC_METTL3_EV_vs_WT_F09.03782.03782.2 0.00516 16-Aug K.HC[160.03]SQVDSVR.G sp|Q14247|SRC8_HUMAN 1 1086.4876 0.16 125645 3782 2 1086.485372 544.2511 Src substrate cortactin OS=Homo sapiens OX=9606 GN=CTTN PE=1 SV=2 6.74 1344.6 - 534491 - - - -2.0884 - 1.549 0.432 - 175.6 1 2 0 -0.0023 9 0 0 0 8.50E+06 5.34E+07 - - - 3.4971 0.9984 221125_WJC_METTL3_EV_vs_WT_F09.03786.03786.3 0.000338 Nov-40 K.VNPEREDSETR.T "sp|Q9Y4A5|TRRAP_HUMAN,tr|H0Y4W2|H0Y4W2_HUMAN,tr|F2Z2U4|F2Z2U4_HUMAN" 3 1330.6113 0.95 125647 3786 3 1330.609638 444.5444 Transformation\transcription domain-associated protein OS=Homo sapiens OX=9606 GN=TRRAP PE=1 SV=3 4.41 1345.1 - 1.58E+06 - - - -1.2656 - 1.608 0.387 - 178.6 1 2 1 -0.0017 11 0 0 0 2.34E+07 2.47E+07 - - - 4.2036 0.9997 221125_WJC_METTL3_EV_vs_WT_F09.03787.03787.2 0.997 18-Oct R.KDSETGENIR.Q "sp|P38646|GRP75_HUMAN,tr|A0A7I2V2S7|A0A7I2V2S7_HUMAN,tr|A0A7I2V2G2|A0A7I2V2G2_HUMAN,tr|A0A7I2V3F7|A0A7I2V3F7_HUMAN,tr|A0A7I2YQB2|A0A7I2YQB2_HUMAN,tr|D6RCD7|D6RCD7_HUMAN" 6 1147.5469 0.42 125648 3787 2 1147.545308 574.7807 "Stress-70 protein, mitochondrial OS=Homo sapiens OX=9606 GN=HSPA9 PE=1 SV=2" 4.68 1345.2 - 859980 - - - -1.4134 - 2.149 0.397 - 319.7 1 2 0 -0.0016 10 0 0 0 2.66E+07 6.41E+07 - - - 4.1081 0.9996 221125_WJC_METTL3_EV_vs_WT_F09.03789.03789.2 0.00381 16-Nov K.KQSQLVQEK.D sp|P40222|TXLNA_HUMAN 1 1086.6033 1.04 125650 3789 2 1086.601294 544.3089 Alpha-taxilin OS=Homo sapiens OX=9606 GN=TXLNA PE=1 SV=3 8.59 1345.5 - 455860 - - - -1.8673 - 2.019 0.398 - 368.7 1 2 0 -0.002 9 0 0 0 4.38E+06 4.21E+06 - - - 4.0127 0.9951 221125_WJC_METTL3_EV_vs_WT_F09.03790.03790.3 0.0143 Aug-44 R.TK[136.11]TENSGEALAK[136.11].V sp|Q9P016|THYN1_HUMAN 1 1263.6641 22.95 125651 3790 3 1263.662754 422.2287 Thymocyte nuclear protein 1 OS=Homo sapiens OX=9606 GN=THYN1 PE=1 SV=1 5.81 1345.6 - 368587 - - - -1.1008 - 1.63 0.305 - 98.2 1 2 1 -0.0014 12 0 0 0 1.43E+08 6.22E+06 - - - 3.2943 0.9995 221125_WJC_METTL3_EV_vs_WT_F09.03794.03794.2 0.00327 14-Aug K.EEFEHQQK[136.11].E "sp|P11142|HSP7C_HUMAN,tr|E9PNE6|E9PNE6_HUMAN,tr|A8K7Q2|A8K7Q2_HUMAN,tr|E9PKE3|E9PKE3_HUMAN,tr|E9PM13|E9PM13_HUMAN,tr|E9PS65|E9PS65_HUMAN" 6 1081.492 3.65 125654 3794 2 1081.491304 541.7533 Heat shock cognate 71 kDa protein OS=Homo sapiens OX=9606 GN=HSPA8 PE=1 SV=1 4.75 1346.2 - 772966 - - - -0.6325 - 1.381 0.415 - 118.7 1 2 0 -0.0007 8 0 0 0 8.82E+07 2.42E+07 - - - 3.0795 0.9751 221125_WJC_METTL3_EV_vs_WT_F09.03796.03796.2 0.802 16-Oct E.VAGTVTGQK[136.11].R "sp|Q86U44|MTA70_HUMAN,tr|F5H6D8|F5H6D8_HUMAN,tr|H0YFV6|H0YFV6_HUMAN,tr|B4DTN4|B4DTN4_HUMAN" 4 867.4905 0.02 125656 3796 2 867.489293 434.7525 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 8.72 1346.3 - 2.95E+06 - - - -1.4271 - 2.176 0.317 - 263 1 1 0 -0.0012 9 0 0 0 7.44E+05 3.81E+07 - - - 3.6313 0.9867 221125_WJC_METTL3_EV_vs_WT_F09.03797.03797.3 0.0029 Sep-40 K.VNPER[166.11]EDSETR[166.11].T "sp|Q9Y4A5|TRRAP_HUMAN,tr|H0Y4W2|H0Y4W2_HUMAN,tr|F2Z2U4|F2Z2U4_HUMAN" 3 1350.6279 0.95 125657 3797 3 1350.625403 451.2166 Transformation\transcription domain-associated protein OS=Homo sapiens OX=9606 GN=TRRAP PE=1 SV=3 4.41 1346.4 - 1.01E+06 - - - -1.8206 - 1.54 0.28 - 106.1 1 2 1 -0.0025 11 0 0 0 2.35E+07 2.47E+07 - - - 2.8877 0.9707 221125_WJC_METTL3_EV_vs_WT_F09.03798.03798.2 0.515 16-Jul R.K[136.11]QDADSLQR[166.11].A "sp|P14324|FPPS_HUMAN,tr|A0A087WVN4|A0A087WVN4_HUMAN,tr|A0A087X1D8|A0A087X1D8_HUMAN" 3 1077.5534 0.16 125658 3798 2 1077.551868 539.784 Farnesyl pyrophosphate synthase OS=Homo sapiens OX=9606 GN=FDPS PE=1 SV=4 5.96 1346.5 - 870704 - - - -1.3809 - 1.329 0.038 - 159.2 1 2 0 -0.0015 9 0 0 0 3.32E+06 2.04E+07 - - - 0.1441 0.9995 221125_WJC_METTL3_EV_vs_WT_F09.03799.03799.2 0.202 16-Oct K.K[136.11]QSQLVQEK[136.11].D sp|P40222|TXLNA_HUMAN 1 1102.6317 1.03 125659 3799 2 1102.630019 552.3231 Alpha-taxilin OS=Homo sapiens OX=9606 GN=TXLNA PE=1 SV=3 8.59 1346.6 - 521052 - - - -1.5454 - 1.952 0.338 - 324.9 1 2 0 -0.0017 9 0 0 0 4.38E+06 4.25E+06 - - - 3.472 0.9172 221125_WJC_METTL3_EV_vs_WT_F09.03802.03802.2 1.66 16-Apr K.NNQITNNQR[166.11].L sp|P00558|PGK1_HUMAN 1 1110.5406 1.21 125662 3802 2 1110.540421 556.2776 Phosphoglycerate kinase 1 OS=Homo sapiens OX=9606 GN=PGK1 PE=1 SV=3 9.75 1347 - 324643 - - - -0.1189 - 0.948 0.046 - 51.7 1 2 0 -0.0001 9 0 0 0 9.67E+07 8.02E+07 - - - -0.7738 0.9923 221125_WJC_METTL3_EV_vs_WT_F09.03804.03804.2 0.12 16-Aug K.VHQLETQNR.A sp|Q16352|AINX_HUMAN 1 1123.5734 1.47 125664 3804 2 1123.577977 562.794 Alpha-internexin OS=Homo sapiens OX=9606 GN=INA PE=1 SV=2 6.72 1347.2 - 296706 - - - 4.0558 - 1.558 0.307 - 301.2 1 2 0 0.0046 9 0 0 0 1.96E+06 1.33E+06 - - - 2.5899 0.9999 221125_WJC_METTL3_EV_vs_WT_F09.03810.03810.3 0.000183 Nov-36 R.KDSETGENIR.Q "sp|P38646|GRP75_HUMAN,tr|A0A7I2V2S7|A0A7I2V2S7_HUMAN,tr|A0A7I2V2G2|A0A7I2V2G2_HUMAN,tr|A0A7I2V3F7|A0A7I2V3F7_HUMAN,tr|A0A7I2YQB2|A0A7I2YQB2_HUMAN,tr|D6RCD7|D6RCD7_HUMAN" 6 1147.5469 0.48 125668 3810 3 1147.548145 383.5229 "Stress-70 protein, mitochondrial OS=Homo sapiens OX=9606 GN=HSPA9 PE=1 SV=2" 4.68 1348.1 - 1.74E+07 - - - 1.0588 - 2.342 0.43 - 268.7 1 2 0 0.0012 10 0 0 0 9.26E+07 1.94E+08 - - - 5.819 0.9708 221125_WJC_METTL3_EV_vs_WT_F09.03811.03811.3 0.00802 Oct-36 R.VDQLKSDQSR.L sp|P04264|K2C1_HUMAN 1 1174.5942 79.36 125669 3811 3 1174.590549 392.5387 "Keratin, type II cytoskeletal 1 OS=Homo sapiens OX=9606 GN=KRT1 PE=1 SV=6" 5.93 1348.1 - 2.68E+06 - - - -3.1211 - 1.847 0.238 - 169.7 1 2 1 -0.0037 10 0 0 0 2.21E+07 2.79E+05 - - - 2.9843 0.973 221125_WJC_METTL3_EV_vs_WT_F09.03814.03814.3 4.41 Jun-36 R.YSDR[166.11]PSSGPR[166.11].T "sp|Q05925|HME1_HUMAN,sp|P19622|HME2_HUMAN" 2 1140.5427 0.001 125672 3814 3 1140.543644 381.1882 Homeobox protein engrailed-1 OS=Homo sapiens OX=9606 GN=EN1 PE=3 SV=3 8.75 1348.4 - 490557 - - - 0.8496 - 1.189 0.209 - 42.9 2 2 0 0.001 10 0 0 0 0.00E+00 3.92E+06 - - - 1.2361 0.9465 221125_WJC_METTL3_EV_vs_WT_F09.03817.03817.3 0.699 Sep-44 K.EEHGPEAC[160.03]DAAK.L sp|O15119|TBX3_HUMAN 1 1312.5354 0.64 125675 3817 3 1312.533306 438.5191 T-box transcription factor TBX3 OS=Homo sapiens OX=9606 GN=TBX3 PE=1 SV=4 4.4 1348.8 - 262735 - - - -1.5801 - 1.04 0.21 - 98.6 1 2 0 -0.0021 12 0 0 0 1.93E+06 3.01E+06 - - - 0.9894 0.8013 221125_WJC_METTL3_EV_vs_WT_F09.03818.03818.2 0.713 22-May R.TK[136.11]TENSGEALAK[136.11].V sp|Q9P016|THYN1_HUMAN 1 1263.6641 31.17 125676 3818 2 1263.663292 632.8393 Thymocyte nuclear protein 1 OS=Homo sapiens OX=9606 GN=THYN1 PE=1 SV=1 5.81 1348.9 - 156131 - - - -0.675 - 1.05 0.175 - 45.7 5 2 1 -0.0009 12 0 0 0 1.78E+07 5.73E+05 - - - 0.1494 1 221125_WJC_METTL3_EV_vs_WT_F09.03829.03829.3 2.13E-06 17/48 R.AVC[160.03]EADQSHGGPR[166.11].S "sp|O14545|TRAD1_HUMAN,tr|F8VNX8|F8VNX8_HUMAN" 2 1392.608 0.7 125685 3829 3 1392.605199 465.2099 TRAF-type zinc finger domain-containing protein 1 OS=Homo sapiens OX=9606 GN=TRAFD1 PE=1 SV=1 5.32 1350.3 - 500991 - - - -1.9977 - 2.262 0.608 - 386.6 1 2 0 -0.0028 13 0 0 0 2.10E+06 3.00E+06 - - - 7.5309 0.9995 221125_WJC_METTL3_EV_vs_WT_F09.03830.03830.2 1.84E-05 18-Aug R.EYEQDQSSSR.D "sp|Q5T200|ZC3HD_HUMAN,tr|A0A7I2V4I5|A0A7I2V4I5_HUMAN" 2 1227.5004 1.46 125686 3830 2 1227.497225 614.7575 Zinc finger CCCH domain-containing protein 13 OS=Homo sapiens OX=9606 GN=ZC3H13 PE=1 SV=1 4.14 1350.4 - 430625 - - - -2.5654 - 1.759 0.542 - 270.7 1 2 0 -0.0031 10 0 0 0 2.00E+06 1.37E+06 - - - 4.6196 0.9934 221125_WJC_METTL3_EV_vs_WT_F09.03835.03835.2 1.68 18-May R.GGSDGYGSGR.G "sp|P22626|ROA2_HUMAN,tr|A0A024RA28|A0A024RA28_HUMAN,tr|A0A7I2V4N1|A0A7I2V4N1_HUMAN,tr|A0A7I2V4S4|A0A7I2V4S4_HUMAN,tr|A0A7I2V323|A0A7I2V323_HUMAN,tr|A0A7I2V3P1|A0A7I2V3P1_HUMAN,tr|A0A7I2V3P7|A0A7I2V3P7_HUMAN" 7 911.3733 1.62 125691 3835 2 911.37319 456.6939 Heterogeneous nuclear ribonucleoproteins A2\B1 OS=Homo sapiens OX=9606 GN=HNRNPA2B1 PE=1 SV=2 5.84 1351 - 225039 - - - -0.1459 - 0.874 0.303 - 89.5 1 2 0 -0.0001 10 0 0 0 1.58E+06 9.73E+05 - - - 0.903 0.997 221125_WJC_METTL3_EV_vs_WT_F09.03836.03836.2 0.00479 22-Jul R.NPPSESEGSDGR[166.11].F "sp|Q8TBX8|PI42C_HUMAN,tr|F8VNT5|F8VNT5_HUMAN,tr|F8VU68|F8VU68_HUMAN" 3 1240.5195 1.16 125692 3836 2 1240.515811 621.267 Phosphatidylinositol 5-phosphate 4-kinase type-2 gamma OS=Homo sapiens OX=9606 GN=PIP4K2C PE=1 SV=3 4.14 1351.2 - 140670 - - - -3.0084 - 1.466 0.365 - 142.7 1 2 0 -0.0037 12 0 0 0 1.09E+06 9.44E+05 - - - 2.7422 0.9705 221125_WJC_METTL3_EV_vs_WT_F09.03846.03846.2 0.684 22-Nov K.SSSSGSVGESSS.K "sp|P13645|K1C10_HUMAN,tr|A0A1B0GVI3|A0A1B0GVI3_HUMAN" 2 1056.4207 - 125700 3846 2 1056.420387 529.2176 "Keratin, type I cytoskeletal 10 OS=Homo sapiens OX=9606 GN=KRT10 PE=1 SV=6" 4 1352.3 - 2.11E+06 - - - -0.3218 - 1.751 0.338 - 321.5 1 1 0 -0.0003 12 0 0 0 - - - - - 3.0113 0.9839 221125_WJC_METTL3_EV_vs_WT_F09.03850.03850.2 0.000247 Sep-32 R.SGGGGGGGGC[160.03]GGGGGVS.S "sp|P13645|K1C10_HUMAN,tr|A0A1B0GVI3|A0A1B0GVI3_HUMAN" 2 1192.4527 - 125704 3850 2 1192.45155 597.2336 "Keratin, type I cytoskeletal 10 OS=Homo sapiens OX=9606 GN=KRT10 PE=1 SV=6" 5.24 1352.7 - 804284 - - - -0.9753 - 1.458 0.532 - 136.5 1 1 0 -0.0012 17 0 0 0 - - - - - 3.897 0.9998 221125_WJC_METTL3_EV_vs_WT_F09.03851.03851.2 1.73E-05 22-Oct R.AAQQQQPSASPR.A sp|Q86U86|PB1_HUMAN 1 1267.6269 1.77 125705 3851 2 1267.626757 634.8207 Protein polybromo-1 OS=Homo sapiens OX=9606 GN=PBRM1 PE=1 SV=1 9.79 1352.8 - 796589 - - - -0.1223 - 2.45 0.382 - 288.3 1 2 0 -0.0002 12 0 0 0 6.96E+06 3.93E+06 - - - 4.2202 0.9986 221125_WJC_METTL3_EV_vs_WT_F09.03854.03854.2 1.92E-05 13/18 K.GQVK[136.11]EEGINK[136.11].S "sp|P09874|PARP1_HUMAN,tr|A0A7I2V3E1|A0A7I2V3E1_HUMAN" 2 1116.611 0.97 125708 3854 2 1116.609412 559.3128 Poly [ADP-ribose] polymerase 1 OS=Homo sapiens OX=9606 GN=PARP1 PE=1 SV=4 6.14 1353.2 - 629854 - - - -1.4114 - 2.694 0.512 - 603.9 1 2 1 -0.0016 10 0 0 0 4.79E+06 4.95E+06 - - - 5.5884 0.9999 221125_WJC_METTL3_EV_vs_WT_F09.03856.03856.3 7.95E-06 Nov-48 R.AVC[160.03]EADQSHGGPR.S "sp|O14545|TRAD1_HUMAN,tr|F8VNX8|F8VNX8_HUMAN" 2 1382.5997 0.7 125710 3856 3 1382.599356 461.8738 TRAF-type zinc finger domain-containing protein 1 OS=Homo sapiens OX=9606 GN=TRAFD1 PE=1 SV=1 5.32 1353.4 - 534059 - - - -0.2568 - 1.863 0.483 - 118 1 2 0 -0.0004 13 0 0 0 2.10E+06 3.00E+06 - - - 5.6118 0.9975 221125_WJC_METTL3_EV_vs_WT_F09.03857.03857.3 2.96E-06 13/44 H.ILC[160.03]SGSNDHTSK[136.11].F sp|Q9C0J8|WDR33_HUMAN 1 1325.6125 1.57 125711 3857 3 1325.610525 442.8781 pre-mRNA 3' end processing protein WDR33 OS=Homo sapiens OX=9606 GN=WDR33 PE=1 SV=2 6.73 1353.6 - 515655 - - - -1.5004 - 2.313 0.567 - 247.1 1 1 0 -0.002 12 0 0 0 3.38E+06 2.15E+06 - - - 7.1853 0.9872 221125_WJC_METTL3_EV_vs_WT_F09.03860.03860.2 0.00128 22-Sep R.LSSSTEQSTSSR[166.11].L "sp|P54792|DVLP1_HUMAN,sp|O14640|DVL1_HUMAN,tr|A0A087WWA7|A0A087WWA7_HUMAN" 3 1278.5927 -1 125714 3860 2 1278.584901 640.3036 Putative segment polarity protein dishevelled homolog DVL1P1 OS=Homo sapiens OX=9606 GN=DVL1P1 PE=5 SV=1 6 1353.9 - 407080 - - - -6.1059 - 1.711 0.418 - 132 1 2 0 -0.0078 12 0 0 0 0.00E+00 0.00E+00 - - - 3.539 0.9933 221125_WJC_METTL3_EV_vs_WT_F09.03870.03870.2 2.25E-05 22-Nov L.TQSVGGDSSADR[166.11].L "sp|Q86U44|MTA70_HUMAN,tr|H0YFV6|H0YFV6_HUMAN" 2 1188.5246 0.02 125722 3870 2 1188.523356 595.2696 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 4.21 1354.9 - 2.73E+06 - - - -1.0702 - 2.296 0.571 - 494.9 1 1 0 -0.0013 12 0 0 0 3.34E+06 1.42E+08 - - - 5.445 0.9999 221125_WJC_METTL3_EV_vs_WT_F09.03871.03871.3 0.0228 14/36 R.SEIQAEQDR[166.11]K[136.11].L "sp|Q16891|MIC60_HUMAN,tr|B9A067|B9A067_HUMAN,tr|C9J406|C9J406_HUMAN,tr|H7C463|H7C463_HUMAN" 4 1220.6116 1.63 125723 3871 3 1220.610085 407.8778 MICOS complex subunit MIC60 OS=Homo sapiens OX=9606 GN=IMMT PE=1 SV=1 4.68 1355 - 2.55E+06 - - - -1.2404 - 2.334 0.427 - 252.4 1 2 0 -0.0015 10 0 0 0 9.07E+07 5.55E+07 - - - 5.7755 0.9997 221125_WJC_METTL3_EV_vs_WT_F09.03872.03872.3 0.000136 Dec-44 K.AGADEER[166.11]AETAR[166.11].L "sp|P78371|TCPB_HUMAN,tr|F8VQ14|F8VQ14_HUMAN,tr|F5GWF6|F5GWF6_HUMAN" 3 1294.6016 0.51 125724 3872 3 1294.600071 432.5412 T-complex protein 1 subunit beta OS=Homo sapiens OX=9606 GN=CCT2 PE=1 SV=4 4.41 1355 - 1.90E+06 - - - -1.2174 - 2.303 0.436 - 258.2 1 2 1 -0.0016 12 0 0 0 2.76E+06 5.46E+06 - - - 5.7128 0.9996 221125_WJC_METTL3_EV_vs_WT_F09.03875.03875.3 0.000375 15/44 K.AGADEERAETAR.L "sp|P78371|TCPB_HUMAN,tr|F8VQ14|F8VQ14_HUMAN,tr|F5GWF6|F5GWF6_HUMAN" 3 1274.5851 0.51 125727 3875 3 1274.583388 425.869 T-complex protein 1 subunit beta OS=Homo sapiens OX=9606 GN=CCT2 PE=1 SV=4 4.41 1355.3 - 944649 - - - -1.3487 - 2.171 0.432 - 384.2 1 2 1 -0.0017 12 0 0 0 2.76E+06 5.41E+06 - - - 5.5046 0.9986 221125_WJC_METTL3_EV_vs_WT_F09.03878.03878.2 0.0982 18-Aug R.SEIQAEQDR[166.11]K[136.11].L "sp|Q16891|MIC60_HUMAN,tr|B9A067|B9A067_HUMAN,tr|C9J406|C9J406_HUMAN,tr|H7C463|H7C463_HUMAN" 4 1220.6116 1.68 125729 3878 2 1220.610329 611.3131 MICOS complex subunit MIC60 OS=Homo sapiens OX=9606 GN=IMMT PE=1 SV=1 4.68 1355.7 - 301974 - - - -1.0405 - 1.775 0.232 - 200 2 2 0 -0.0013 10 0 0 0 1.31E+07 7.78E+06 - - - 2.2213 0.9994 221125_WJC_METTL3_EV_vs_WT_F09.03879.03879.2 0.000359 22-Jul K.ASPQENGPAVHK.G "sp|Q5JSZ5|PRC2B_HUMAN,tr|A0A804HIM8|A0A804HIM8_HUMAN" 2 1233.6102 1.36 125730 3879 2 1233.609161 617.8124 Protein PRRC2B OS=Homo sapiens OX=9606 GN=PRRC2B PE=1 SV=2 6.79 1355.8 - 273765 - - - -0.8414 - 1.391 0.423 - 160.6 1 2 0 -0.001 12 0 0 0 1.43E+06 1.06E+06 - - - 3.0333 0.9982 221125_WJC_METTL3_EV_vs_WT_F09.03882.03882.2 0.000307 18-Jul R.AAQMHSGYQR.R sp|Q96PK6|RBM14_HUMAN 1 1147.5193 -1 125733 3882 2 1147.515426 574.7669 RNA-binding protein 14 OS=Homo sapiens OX=9606 GN=RBM14 PE=1 SV=2 8.8 1356.2 - 188119 - - - -3.3551 - 1.732 0.402 - 213.5 1 2 0 -0.0039 10 0 0 0 0.00E+00 0.00E+00 - - - 3.5422 0.9999 221125_WJC_METTL3_EV_vs_WT_F09.03888.03888.3 0.000904 14/36 R.SEIQAEQDRK.L "sp|Q16891|MIC60_HUMAN,tr|B9A067|B9A067_HUMAN,tr|C9J406|C9J406_HUMAN,tr|H7C463|H7C463_HUMAN" 4 1202.5891 1.66 125738 3888 3 1202.587412 401.8703 MICOS complex subunit MIC60 OS=Homo sapiens OX=9606 GN=IMMT PE=1 SV=1 4.68 1357 - 1.48E+07 - - - -1.4278 - 2.409 0.439 - 304.1 1 2 0 -0.0017 10 0 0 0 9.28E+07 5.58E+07 - - - 6.0016 0.9721 221125_WJC_METTL3_EV_vs_WT_F09.03889.03889.2 0.567 12-Apr K.KDMMDIK.Y sp|Q96RL7|VP13A_HUMAN 1 879.4194 3.14 125739 3889 2 879.420018 440.717 Vacuolar protein sorting-associated protein 13A OS=Homo sapiens OX=9606 GN=VPS13A PE=1 SV=2 5.96 1357 - 3.77E+06 - - - 0.6914 - 0.967 0.149 - 98.6 1 2 0 0.0006 7 0 0 0 1.67E+08 5.32E+07 - - - 0.035 0.9997 221125_WJC_METTL3_EV_vs_WT_F09.03891.03891.3 0.00874 Oct-36 R.AAQMHSGYQR.R sp|Q96PK6|RBM14_HUMAN 1 1147.5193 1.67 125741 3891 3 1147.516073 383.5137 RNA-binding protein 14 OS=Homo sapiens OX=9606 GN=RBM14 PE=1 SV=2 8.8 1357.1 - 2.75E+06 - - - -2.7912 - 1.962 0.42 - 187.6 1 2 0 -0.0032 10 0 0 0 7.47E+06 4.49E+06 - - - 5.19 0.9998 221125_WJC_METTL3_EV_vs_WT_F09.03892.03892.2 0.00492 18-Nov R.SEIQAEQDRK.L "sp|Q16891|MIC60_HUMAN,tr|B9A067|B9A067_HUMAN,tr|C9J406|C9J406_HUMAN,tr|H7C463|H7C463_HUMAN" 4 1202.5891 1.57 125742 3892 2 1202.587165 602.3018 MICOS complex subunit MIC60 OS=Homo sapiens OX=9606 GN=IMMT PE=1 SV=1 4.68 1357.2 - 1.68E+06 - - - -1.6331 - 2.166 0.482 - 499.7 1 2 0 -0.002 10 0 0 0 1.33E+07 8.46E+06 - - - 4.7578 0.9873 221125_WJC_METTL3_EV_vs_WT_F09.03898.03898.2 2.70E-06 22-Oct L.TQSVGGDSSADR.L "sp|Q86U44|MTA70_HUMAN,tr|H0YFV6|H0YFV6_HUMAN" 2 1178.5164 0.02 125748 3898 2 1178.514677 590.2655 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 4.21 1357.8 - 385589 - - - -1.4264 - 1.968 0.506 - 369.9 1 1 0 -0.0017 12 0 0 0 3.34E+06 1.42E+08 - - - 4.5591 0.8336 221125_WJC_METTL3_EV_vs_WT_F09.03901.03901.2 0.000352 26-Jul F.GSSVGSSASSSATR[166.11].R sp|Q8TB72|PUM2_HUMAN 1 1249.5774 -1 125751 3901 2 1249.582939 625.796 Pumilio homolog 2 OS=Homo sapiens OX=9606 GN=PUM2 PE=1 SV=2 9.75 1358.2 - 271022 - - - 4.4391 - 1.414 0.525 - 136.7 1 1 0 0.0055 14 0 0 0 0.00E+00 0.00E+00 - - - 3.7862 0.9999 221125_WJC_METTL3_EV_vs_WT_F09.03907.03907.3 3.16E-06 Dec-36 K.TSYAQHQQVR[166.11].Q "sp|P61247|RS3A_HUMAN,tr|H0Y8L7|H0Y8L7_HUMAN,tr|D6R9B6|D6R9B6_HUMAN,tr|H0Y9Y4|H0Y9Y4_HUMAN,tr|D6RAS7|D6RAS7_HUMAN,tr|D6RB09|D6RB09_HUMAN,tr|E9PFI5|E9PFI5_HUMAN,tr|D6RAT0|D6RAT0_HUMAN,tr|D6RG13|D6RG13_HUMAN" 9 1226.6032 0.93 125755 3907 3 1226.599712 409.875 40S ribosomal protein S3a OS=Homo sapiens OX=9606 GN=RPS3A PE=1 SV=2 8.44 1359 - 2.35E+07 - - - -2.8061 - 2.419 0.535 - 347.9 1 2 0 -0.0034 10 0 0 0 2.85E+08 3.06E+08 - - - 7.0835 0.9998 221125_WJC_METTL3_EV_vs_WT_F09.03909.03909.2 8.51E-06 18-Dec K.TSYAQHQQVR[166.11].Q "sp|P61247|RS3A_HUMAN,tr|H0Y8L7|H0Y8L7_HUMAN,tr|D6R9B6|D6R9B6_HUMAN,tr|H0Y9Y4|H0Y9Y4_HUMAN,tr|D6RAS7|D6RAS7_HUMAN,tr|D6RB09|D6RB09_HUMAN,tr|E9PFI5|E9PFI5_HUMAN,tr|D6RAT0|D6RAT0_HUMAN,tr|D6RG13|D6RG13_HUMAN" 9 1226.6032 0.97 125757 3909 2 1226.600616 614.3089 40S ribosomal protein S3a OS=Homo sapiens OX=9606 GN=RPS3A PE=1 SV=2 8.44 1359.1 - 1.72E+06 - - - -2.0691 - 2.308 0.551 - 595.1 1 2 0 -0.0025 10 0 0 0 2.51E+07 2.60E+07 - - - 5.4445 0.9996 221125_WJC_METTL3_EV_vs_WT_F09.03913.03913.3 0.869 Dec-36 R.DTTDK[136.11]GQQLR[166.11].K "sp|Q13144|EI2BE_HUMAN,tr|A0A3B3IUB1|A0A3B3IUB1_HUMAN" 2 1178.601 4.21 125761 3913 3 1178.59928 393.8743 Translation initiation factor eIF-2B subunit epsilon OS=Homo sapiens OX=9606 GN=EIF2B5 PE=1 SV=3 5.96 1359.5 - 1.10E+06 - - - -1.4891 - 2.326 0.41 - 304 1 2 1 -0.0018 10 0 0 0 3.28E+07 7.78E+06 - - - 5.5759 0.9921 221125_WJC_METTL3_EV_vs_WT_F09.03914.03914.2 2.12E-06 16-Nov T.SYAQHQQVR.Q "sp|P61247|RS3A_HUMAN,tr|H0Y8L7|H0Y8L7_HUMAN,tr|D6R9B6|D6R9B6_HUMAN,tr|H0Y9Y4|H0Y9Y4_HUMAN,tr|D6RAS7|D6RAS7_HUMAN,tr|D6RB09|D6RB09_HUMAN,tr|E9PFI5|E9PFI5_HUMAN,tr|D6RAT0|D6RAT0_HUMAN,tr|D6RG13|D6RG13_HUMAN" 9 1115.5472 0.97 125762 3914 2 1115.54586 558.7809 40S ribosomal protein S3a OS=Homo sapiens OX=9606 GN=RPS3A PE=1 SV=2 8.49 1359.6 - 1.03E+06 - - - -1.2057 - 1.934 0.579 - 491 1 1 0 -0.0013 9 0 0 0 1.29E+07 1.33E+07 - - - 5.2253 0.968 221125_WJC_METTL3_EV_vs_WT_F09.03915.03915.2 2.89E-05 13/14 S.YAQHQQVR[166.11].Q "sp|P61247|RS3A_HUMAN,tr|H0Y8L7|H0Y8L7_HUMAN,tr|D6R9B6|D6R9B6_HUMAN,tr|H0Y9Y4|H0Y9Y4_HUMAN,tr|D6RAS7|D6RAS7_HUMAN,tr|D6RB09|D6RB09_HUMAN,tr|E9PFI5|E9PFI5_HUMAN,tr|D6RAT0|D6RAT0_HUMAN,tr|D6RG13|D6RG13_HUMAN" 9 1038.5234 0.89 125763 3915 2 1038.521935 520.269 40S ribosomal protein S3a OS=Homo sapiens OX=9606 GN=RPS3A PE=1 SV=2 8.75 1359.8 - 957116 - - - -1.4559 - 1.883 0.326 - 852.2 1 1 0 -0.0015 8 0 0 0 1.11E+07 1.25E+07 - - - 3.3571 0.9879 221125_WJC_METTL3_EV_vs_WT_F09.03916.03916.2 4.52E-07 16-Dec T.SYAQHQQVR[166.11].Q "sp|P61247|RS3A_HUMAN,tr|H0Y8L7|H0Y8L7_HUMAN,tr|D6R9B6|D6R9B6_HUMAN,tr|H0Y9Y4|H0Y9Y4_HUMAN,tr|D6RAS7|D6RAS7_HUMAN,tr|D6RB09|D6RB09_HUMAN,tr|E9PFI5|E9PFI5_HUMAN,tr|D6RAT0|D6RAT0_HUMAN,tr|D6RG13|D6RG13_HUMAN" 9 1125.5555 0.99 125764 3916 2 1125.553204 563.785 40S ribosomal protein S3a OS=Homo sapiens OX=9606 GN=RPS3A PE=1 SV=2 8.49 1359.9 - 919832 - - - -2.0177 - 2.067 0.574 - 553.6 1 1 0 -0.0023 9 0 0 0 1.32E+07 1.33E+07 - - - 5.3805 0.9117 221125_WJC_METTL3_EV_vs_WT_F09.03919.03919.2 1.43E-06 14-Dec S.YAQHQQVR.Q "sp|P61247|RS3A_HUMAN,tr|H0Y8L7|H0Y8L7_HUMAN,tr|D6R9B6|D6R9B6_HUMAN,tr|H0Y9Y4|H0Y9Y4_HUMAN,tr|D6RAS7|D6RAS7_HUMAN,tr|D6RB09|D6RB09_HUMAN,tr|E9PFI5|E9PFI5_HUMAN,tr|D6RAT0|D6RAT0_HUMAN,tr|D6RG13|D6RG13_HUMAN" 9 1028.5152 0.89 125767 3919 2 1028.512094 515.2649 40S ribosomal protein S3a OS=Homo sapiens OX=9606 GN=RPS3A PE=1 SV=2 8.75 1360.3 - 578142 - - - -2.9975 - 1.861 0.332 - 755.7 1 1 0 -0.0031 8 0 0 0 1.11E+07 1.25E+07 - - - 3.3654 0.9999 221125_WJC_METTL3_EV_vs_WT_F09.03923.03923.2 5.28E-05 22-Sep R.AAQQQQPSASPR[166.11].A sp|Q86U86|PB1_HUMAN 1 1277.6352 1.77 125770 3923 2 1277.633917 639.8249 Protein polybromo-1 OS=Homo sapiens OX=9606 GN=PBRM1 PE=1 SV=1 9.79 1360.9 - 219745 - - - -0.9901 - 2.166 0.564 - 155.9 1 2 0 -0.0013 12 0 0 0 6.96E+06 3.93E+06 - - - 5.2399 1 221125_WJC_METTL3_EV_vs_WT_F09.03925.03925.2 2.06E-07 18-Dec K.TSYAQHQQVR.Q "sp|P61247|RS3A_HUMAN,tr|H0Y8L7|H0Y8L7_HUMAN,tr|D6R9B6|D6R9B6_HUMAN,tr|H0Y9Y4|H0Y9Y4_HUMAN,tr|D6RAS7|D6RAS7_HUMAN,tr|D6RB09|D6RB09_HUMAN,tr|E9PFI5|E9PFI5_HUMAN,tr|D6RAT0|D6RAT0_HUMAN,tr|D6RG13|D6RG13_HUMAN" 9 1216.5949 0.94 125771 3925 2 1216.592608 609.3047 40S ribosomal protein S3a OS=Homo sapiens OX=9606 GN=RPS3A PE=1 SV=2 8.44 1361.1 - 5.20E+06 - - - -1.8708 - 2.418 0.581 - 581 1 2 0 -0.0023 10 0 0 0 2.44E+07 2.60E+07 - - - 5.7961 0.9998 221125_WJC_METTL3_EV_vs_WT_F09.03927.03927.3 1.33E-08 Oct-36 K.TKYDEETTAK.A "sp|Q13948|CASP_HUMAN,sp|P39880|CUX1_HUMAN,tr|A0A2R8Y8D0|A0A2R8Y8D0_HUMAN,tr|A0A2R8Y852|A0A2R8Y852_HUMAN,tr|A0A2R8YDI1|A0A2R8YDI1_HUMAN" 5 1184.5561 0.62 125773 3927 3 1184.553669 395.8593 Protein CASP OS=Homo sapiens OX=9606 GN=CUX1 PE=1 SV=2 4.68 1361.2 - 3.61E+06 - - - -2.0506 - 2.179 0.533 - 165.5 1 2 1 -0.0024 10 0 0 0 5.36E+07 8.60E+07 - - - 6.7564 0.9087 221125_WJC_METTL3_EV_vs_WT_F09.03928.03928.3 0.00279 16/44 R.QGSVTAPGGHPR[166.11].H sp|P48634|PRC2A_HUMAN 1 1172.5926 1.46 125774 3928 3 1172.583928 391.8715 Protein PRRC2A OS=Homo sapiens OX=9606 GN=PRRC2A PE=1 SV=3 9.76 1361.2 - 1.61E+06 - - - -7.3862 - 2.236 0.214 - 318.9 1 2 0 -0.0087 12 0 0 0 4.36E+07 2.98E+07 - - - 3.154 0.8604 221125_WJC_METTL3_EV_vs_WT_F09.03930.03930.3 0.237 Aug-32 R.EK[136.11]EALEQQR[166.11].Q sp|Q92922|SMRC1_HUMAN 1 1147.5952 0.001 125776 3930 3 1147.593176 383.539 SWI\SNF complex subunit SMARCC1 OS=Homo sapiens OX=9606 GN=SMARCC1 PE=1 SV=3 4.79 1361.4 - 1.22E+06 - - - -1.782 - 1.499 0.141 - 106.3 1 2 1 -0.002 9 0 0 0 0.00E+00 6.95E+06 - - - 1.3314 0.8787 221125_WJC_METTL3_EV_vs_WT_F09.03939.03939.2 4.78 20-May R.ESESGGLRPNK.Q sp|Q96G25|MED8_HUMAN 1 1172.5786 12.59 125785 3939 2 1172.577169 587.2966 Mediator of RNA polymerase II transcription subunit 8 OS=Homo sapiens OX=9606 GN=MED8 PE=1 SV=2 6.24 1362.5 - 262148 - - - -1.1905 - 1.018 0.064 - 54.5 9 2 0 -0.0014 11 0 0 0 1.51E+06 1.20E+05 - - - -0.8647 0.9848 221125_WJC_METTL3_EV_vs_WT_F09.03941.03941.2 0.0896 14-Aug K.K[136.11]QEDFEQK[136.11].Y "sp|Q8N9T8|KRI1_HUMAN,tr|F8WFC1|F8WFC1_HUMAN,tr|A0A494C108|A0A494C108_HUMAN" 3 1066.5266 1.15 125787 3941 2 1066.520048 534.2706 Protein KRI1 homolog OS=Homo sapiens OX=9606 GN=KRI1 PE=1 SV=3 4.68 1362.8 - 198444 - - - -6.133 - 1.786 0.349 - 201.2 1 2 0 -0.0065 8 0 0 0 2.30E+06 2.01E+06 - - - 3.3658 0.9918 221125_WJC_METTL3_EV_vs_WT_F09.03942.03942.2 0.726 16-May R.LTEAKPVDK.V "sp|P52815|RM12_HUMAN,tr|B4DLN1|B4DLN1_HUMAN" 2 999.5601 2.4 125788 3942 2 999.559054 500.7873 "39S ribosomal protein L12, mitochondrial OS=Homo sapiens OX=9606 GN=MRPL12 PE=1 SV=2" 6.07 1362.9 - 188412 - - - -1.0074 - 1.162 0.219 - 83.4 3 2 0 -0.001 9 0 0 0 1.14E+06 4.75E+05 - - - 0.8795 1 221125_WJC_METTL3_EV_vs_WT_F09.03944.03944.2 3.57E-06 14/26 R.GSGGGSSGGSIGGR.G sp|P04264|K2C1_HUMAN 1 1091.4956 13.86 125789 3944 2 1091.493469 546.7551 "Keratin, type II cytoskeletal 1 OS=Homo sapiens OX=9606 GN=KRT1 PE=1 SV=6" 9.75 1363.1 - 443982 - - - -1.9185 - 3.241 0.557 - 787.3 1 2 0 -0.0021 14 0 0 0 6.76E+06 4.88E+05 - - - 6.1052 0.9994 221125_WJC_METTL3_EV_vs_WT_F09.03946.03946.3 0.00142 Oct-36 K.TK[136.11]YDEETTAK[136.11].A "sp|Q13948|CASP_HUMAN,sp|P39880|CUX1_HUMAN,tr|A0A2R8Y8D0|A0A2R8Y8D0_HUMAN,tr|A0A2R8Y852|A0A2R8Y852_HUMAN,tr|A0A2R8YDI1|A0A2R8YDI1_HUMAN" 5 1200.5845 0.61 125790 3946 3 1200.582888 401.2021 Protein CASP OS=Homo sapiens OX=9606 GN=CUX1 PE=1 SV=2 4.68 1363.3 - 8.37E+06 - - - -1.341 - 1.851 0.431 - 182.8 1 2 1 -0.0016 10 0 0 0 5.36E+07 8.79E+07 - - - 5.143 0.9977 221125_WJC_METTL3_EV_vs_WT_F09.03947.03947.2 2.96E-06 18-Oct K.TKYDEETTAK.A "sp|Q13948|CASP_HUMAN,sp|P39880|CUX1_HUMAN,tr|A0A2R8Y8D0|A0A2R8Y8D0_HUMAN,tr|A0A2R8Y852|A0A2R8Y852_HUMAN,tr|A0A2R8YDI1|A0A2R8YDI1_HUMAN" 5 1184.5561 0.79 125791 3947 2 1184.553906 593.2853 Protein CASP OS=Homo sapiens OX=9606 GN=CUX1 PE=1 SV=2 4.68 1363.4 - 3.05E+06 - - - -1.8505 - 1.85 0.587 - 211.4 1 2 1 -0.0022 10 0 0 0 1.58E+07 1.99E+07 - - - 5.0931 1 221125_WJC_METTL3_EV_vs_WT_F09.03948.03948.2 4.26E-06 18-Nov K.TK[136.11]YDEETTAK[136.11].A "sp|Q13948|CASP_HUMAN,sp|P39880|CUX1_HUMAN,tr|A0A2R8Y8D0|A0A2R8Y8D0_HUMAN,tr|A0A2R8Y852|A0A2R8Y852_HUMAN,tr|A0A2R8YDI1|A0A2R8YDI1_HUMAN" 5 1200.5845 0.79 125792 3948 2 1200.58257 601.2995 Protein CASP OS=Homo sapiens OX=9606 GN=CUX1 PE=1 SV=2 4.68 1363.5 - 2.24E+06 - - - -1.6059 - 2.229 0.615 - 284.9 1 2 1 -0.0019 10 0 0 0 1.58E+07 1.99E+07 - - - 5.8202 0.9995 221125_WJC_METTL3_EV_vs_WT_F09.03964.03964.2 5.90E-06 14-Sep K.SFATASHR[166.11].N "sp|Q9NYF8|BCLF1_HUMAN,tr|E9PKI6|E9PKI6_HUMAN,tr|A0A1W2PQ43|A0A1W2PQ43_HUMAN,tr|E9PK91|E9PK91_HUMAN,tr|E9PK09|E9PK09_HUMAN,tr|E9PQN2|E9PQN2_HUMAN" 6 885.4332 1.94 125806 3964 2 885.432825 443.7239 Bcl-2-associated transcription factor 1 OS=Homo sapiens OX=9606 GN=BCLAF1 PE=1 SV=2 9.49 1365.3 - 1.10E+06 - - - -0.4631 - 1.693 0.33 - 293 1 2 0 -0.0004 8 0 0 0 1.09E+07 5.62E+06 - - - 3.0662 1 221125_WJC_METTL3_EV_vs_WT_F09.03967.03967.2 3.68E-06 20-Dec K.NSDIEQSSDSK.V "sp|P0DJD0|RGPD1_HUMAN,sp|Q7Z3J3|RGPD4_HUMAN,sp|O14715|RGPD8_HUMAN,sp|P49792|RBP2_HUMAN,sp|P0DJD1|RGPD2_HUMAN,sp|A6NKT7|RGPD3_HUMAN,sp|Q99666|RGPD5_HUMAN,tr|A0A286YES2|A0A286YES2_HUMAN,tr|F8VYC4|F8VYC4_HUMAN,tr|H7BZ48|H7BZ48_HUMAN,tr|J3KNE0|J3KNE0_HUMAN,tr|A0A1W2PNU4|A0A1W2PNU4_HUMAN,tr|J3KQ37|J3KQ37_HUMAN" 13 1208.5157 1.11 125809 3967 2 1208.515022 605.2651 RANBP2-like and GRIP domain-containing protein 1 OS=Homo sapiens OX=9606 GN=RGPD1 PE=2 SV=1 4.03 1365.7 - 456802 - - - -0.5527 - 2.58 0.604 - 712.6 1 2 0 -0.0007 11 0 0 0 7.77E+06 7.01E+06 - - - 6.0659 0.9995 221125_WJC_METTL3_EV_vs_WT_F09.03968.03968.2 0.00401 22-Nov R.QGSVTAPGGHPR.H sp|P48634|PRC2A_HUMAN 1 1162.5843 1.91 125810 3968 2 1162.581595 582.2994 Protein PRRC2A OS=Homo sapiens OX=9606 GN=PRRC2A PE=1 SV=3 9.76 1365.9 - 342217 - - - -2.3431 - 2.267 0.425 - 366.8 1 2 0 -0.0027 12 0 0 0 3.04E+06 1.59E+06 - - - 4.3327 0.9996 221125_WJC_METTL3_EV_vs_WT_F09.03978.03978.3 0.0143 15/36 R.SVHK[136.11]VEPITK[136.11].H "sp|P25787|PSA2_HUMAN,tr|A0A024RA52|A0A024RA52_HUMAN,tr|A0A7I2V2H3|A0A7I2V2H3_HUMAN" 3 1152.6838 0.02 125818 3978 3 1152.683915 385.2352 Proteasome subunit alpha type-2 OS=Homo sapiens OX=9606 GN=PSMA2 PE=1 SV=2 8.34 1367.2 - 2.32E+06 - - - 0.1353 - 2.482 0.379 - 294.8 1 2 1 0.0002 10 0 0 0 3.13E+05 1.28E+07 - - - 5.4203 0.9761 221125_WJC_METTL3_EV_vs_WT_F09.03979.03979.2 0.00678 14-Aug N.R[166.11]NTTIPTK[136.11].K "sp|P38646|GRP75_HUMAN,sp|P54652|HSP72_HUMAN,sp|P11142|HSP7C_HUMAN,tr|E9PNE6|E9PNE6_HUMAN,tr|A8K7Q2|A8K7Q2_HUMAN,tr|E9PKE3|E9PKE3_HUMAN,tr|A0A7I2V2S7|A0A7I2V2S7_HUMAN,tr|A0A7I2V2G2|A0A7I2V2G2_HUMAN,tr|E9PS65|E9PS65_HUMAN,tr|A0A7I2YQB2|A0A7I2YQB2_HUMAN,tr|D6RCD7|D6RCD7_HUMAN" 11 947.5519 0.13 125819 3979 2 947.552136 474.7832 "Stress-70 protein, mitochondrial OS=Homo sapiens OX=9606 GN=HSPA9 PE=1 SV=2" 11 1367.3 - 2.19E+06 - - - 0.2491 - 1.588 0.383 - 305.2 1 1 0 0.0002 8 0 0 0 3.36E+06 2.68E+07 - - - 3.2646 0.9985 221125_WJC_METTL3_EV_vs_WT_F09.03980.03980.3 9.54E-07 15/48 N.STAGASGGAYEHR.Y "sp|P31943|HNRH1_HUMAN,tr|H0YB39|H0YB39_HUMAN,tr|G8JLB6|G8JLB6_HUMAN" 3 1262.564 0.98 125820 3980 3 1262.564475 421.8619 Heterogeneous nuclear ribonucleoprotein H OS=Homo sapiens OX=9606 GN=HNRNPH1 PE=1 SV=4 6.47 1367.4 - 1.84E+06 - - - 0.3944 - 3.043 0.542 - 400.3 1 1 0 0.0005 13 0 0 0 6.11E+06 6.25E+06 - - - 7.5999 0.9978 221125_WJC_METTL3_EV_vs_WT_F09.03981.03981.3 0.000445 20/48 N.STAGASGGAYEHR[166.11].Y "sp|P31943|HNRH1_HUMAN,tr|H0YB39|H0YB39_HUMAN,tr|G8JLB6|G8JLB6_HUMAN" 3 1272.5722 0.98 125821 3981 3 1272.572405 425.198 Heterogeneous nuclear ribonucleoprotein H OS=Homo sapiens OX=9606 GN=HNRNPH1 PE=1 SV=4 6.47 1367.4 - 1.37E+06 - - - 0.1242 - 3.565 0.449 - 856.9 1 1 0 0.0002 13 0 0 0 6.11E+06 6.25E+06 - - - 6.9924 1 221125_WJC_METTL3_EV_vs_WT_F09.03982.03982.2 3.24E-07 13/20 K.NSDIEQSSDSK[136.11].V "sp|P0DJD0|RGPD1_HUMAN,sp|Q7Z3J3|RGPD4_HUMAN,sp|O14715|RGPD8_HUMAN,sp|P49792|RBP2_HUMAN,sp|P0DJD1|RGPD2_HUMAN,sp|A6NKT7|RGPD3_HUMAN,sp|Q99666|RGPD5_HUMAN,tr|A0A286YES2|A0A286YES2_HUMAN,tr|F8VYC4|F8VYC4_HUMAN,tr|H7BZ48|H7BZ48_HUMAN,tr|J3KNE0|J3KNE0_HUMAN,tr|A0A1W2PNU4|A0A1W2PNU4_HUMAN,tr|J3KQ37|J3KQ37_HUMAN" 13 1216.5299 1.11 125822 3982 2 1216.529965 609.2722 RANBP2-like and GRIP domain-containing protein 1 OS=Homo sapiens OX=9606 GN=RGPD1 PE=2 SV=1 4.03 1367.5 - 1.22E+06 - - - 0.0617 - 2.552 0.589 - 768.4 1 2 0 0.0001 11 0 0 0 7.77E+06 7.01E+06 - - - 5.9258 0.8891 221125_WJC_METTL3_EV_vs_WT_F09.03984.03984.3 3.43 Aug-44 R.QLEDGDQPESKK.L "sp|Q92945|FUBP2_HUMAN,tr|M0R0I5|M0R0I5_HUMAN,tr|M0R0C6|M0R0C6_HUMAN,tr|A0A087WTP3|A0A087WTP3_HUMAN" 4 1372.647 1.09 125824 3984 3 1372.645264 458.5563 Far upstream element-binding protein 2 OS=Homo sapiens OX=9606 GN=KHSRP PE=1 SV=4 4.32 1367.8 - 645824 - - - -1.2924 - 1.215 0.124 - 69.6 1 2 0 -0.0018 12 0 0 0 2.96E+06 2.70E+06 - - - 0.4618 0.9941 221125_WJC_METTL3_EV_vs_WT_F09.03985.03985.3 0.0297 Sep-44 R.QLEDGDQPESK[136.11]K[136.11].L "sp|Q92945|FUBP2_HUMAN,tr|M0R0I5|M0R0I5_HUMAN,tr|M0R0C6|M0R0C6_HUMAN,tr|A0A087WTP3|A0A087WTP3_HUMAN" 4 1388.6754 1.09 125825 3985 3 1388.677147 463.8991 Far upstream element-binding protein 2 OS=Homo sapiens OX=9606 GN=KHSRP PE=1 SV=4 4.32 1367.8 - 542756 - - - 1.2307 - 1.518 0.23 - 134.1 1 2 0 0.0017 12 0 0 0 2.96E+06 2.70E+06 - - - 2.2608 0.931 221125_WJC_METTL3_EV_vs_WT_F09.03987.03987.2 0.247 16-Jun K.IHAEEKLDK.A "sp|O75410|TACC1_HUMAN,tr|E7EVI4|E7EVI4_HUMAN,tr|B4E3H6|B4E3H6_HUMAN,tr|H0YAY0|H0YAY0_HUMAN,tr|H0YBT8|H0YBT8_HUMAN,tr|E7ET87|E7ET87_HUMAN" 6 1081.5768 1.04 125827 3987 2 1081.575305 541.7957 Transforming acidic coiled-coil-containing protein 1 OS=Homo sapiens OX=9606 GN=TACC1 PE=1 SV=2 5.45 1368.1 - 298218 - - - -1.3582 - 1.227 0.207 - 123.6 1 2 1 -0.0015 9 0 0 0 1.37E+06 1.32E+06 - - - 1.1613 0.9999 221125_WJC_METTL3_EV_vs_WT_F09.03991.03991.3 6.98E-06 14/52 K.VVNGAAASQPPSKR.K sp|O75533|SF3B1_HUMAN 1 1380.7474 1.26 125831 3991 3 1380.747879 461.2564 Splicing factor 3B subunit 1 OS=Homo sapiens OX=9606 GN=SF3B1 PE=1 SV=3 11 1368.6 - 269846 - - - 0.3752 - 2.231 0.432 - 219.6 1 2 0 0.0005 14 0 0 0 7.64E+07 6.04E+07 - - - 5.4888 0.9997 221125_WJC_METTL3_EV_vs_WT_F09.03994.03994.2 0.0298 20-Jun K.EC[160.03]VGASNQNC[160.03]R.T "sp|O00400|ACATN_HUMAN,tr|A0A2R8YF57|A0A2R8YF57_HUMAN,tr|H7C562|H7C562_HUMAN,tr|H7C577|H7C577_HUMAN" 4 1293.519 1.97 125834 3994 2 1293.517531 647.7668 Acetyl-coenzyme A transporter 1 OS=Homo sapiens OX=9606 GN=SLC33A1 PE=1 SV=1 6.08 1369 - 148306 - - - -1.1496 - 1.171 0.626 - 106.9 1 2 0 -0.0015 11 0 0 0 1.11E+06 5.62E+05 - - - 4.0912 0.9998 221125_WJC_METTL3_EV_vs_WT_F09.03995.03995.2 0.000227 20-Sep K.TLQNTSSEGSR.L sp|Q06787|FMR1_HUMAN 1 1178.5527 2.48 125835 3995 2 1178.552925 590.2836 Synaptic functional regulator FMR1 OS=Homo sapiens OX=9606 GN=FMR1 PE=1 SV=1 5.66 1369.1 - 121764 - - - 0.1536 - 1.64 0.548 - 248.1 1 2 0 0.0002 11 0 0 0 5.77E+05 2.32E+05 - - - 4.4267 0.8939 221125_WJC_METTL3_EV_vs_WT_F09.03996.03996.2 1.95 20-Mar K.EC[160.03]VGASNQNC[160.03]R[166.11].T "sp|O00400|ACATN_HUMAN,tr|A0A2R8YF57|A0A2R8YF57_HUMAN,tr|H7C562|H7C562_HUMAN,tr|H7C577|H7C577_HUMAN" 4 1303.5273 1.97 125836 3996 2 1303.52626 652.7709 Acetyl-coenzyme A transporter 1 OS=Homo sapiens OX=9606 GN=SLC33A1 PE=1 SV=1 6.08 1369.3 - 112482 - - - -0.7886 - 0.744 0.162 - 21.8 5 2 0 -0.001 11 0 0 0 1.11E+06 5.62E+05 - - - -0.875 0.9998 221125_WJC_METTL3_EV_vs_WT_F09.04000.04000.3 1.25E-05 15/48 K.VSSAEGAAKEEPK.R "sp|P05114|HMGN1_HUMAN,tr|F2Z2W6|F2Z2W6_HUMAN,tr|F2Z2Y5|F2Z2Y5_HUMAN,tr|A6NEL0|A6NEL0_HUMAN,tr|H7BXJ5|H7BXJ5_HUMAN,tr|A0A494C035|A0A494C035_HUMAN" 6 1301.6463 0.91 125838 4000 3 1301.646761 434.8894 Non-histone chromosomal protein HMG-14 OS=Homo sapiens OX=9606 GN=HMGN1 PE=1 SV=3 4.79 1369.8 - 6.49E+06 - - - 0.3465 - 3.085 0.422 - 358 1 2 1 0.0005 13 0 0 0 2.06E+08 2.27E+08 - - - 6.2992 0.9999 221125_WJC_METTL3_EV_vs_WT_F09.04002.04002.3 2.15E-05 16/52 K.VVNGAAASQPPSK[136.11]R[166.11].K sp|O75533|SF3B1_HUMAN 1 1398.7698 1.26 125840 4002 3 1398.768991 467.2639 Splicing factor 3B subunit 1 OS=Homo sapiens OX=9606 GN=SF3B1 PE=1 SV=3 11 1370 - 1.56E+06 - - - -0.6005 - 2.877 0.402 - 264.1 1 2 0 -0.0008 14 0 0 0 7.64E+07 6.04E+07 - - - 5.83 1 221125_WJC_METTL3_EV_vs_WT_F09.04005.04005.2 4.54E-09 16/24 K.VSSAEGAAK[136.11]EEPK[136.11].R "sp|P05114|HMGN1_HUMAN,tr|F2Z2W6|F2Z2W6_HUMAN,tr|F2Z2Y5|F2Z2Y5_HUMAN,tr|A6NEL0|A6NEL0_HUMAN,tr|H7BXJ5|H7BXJ5_HUMAN,tr|A0A494C035|A0A494C035_HUMAN" 6 1317.6747 0.98 125843 4005 2 1317.674383 659.8446 Non-histone chromosomal protein HMG-14 OS=Homo sapiens OX=9606 GN=HMGN1 PE=1 SV=3 4.79 1370.3 - 543055 - - - -0.2482 - 2.845 0.623 - 857.4 1 2 1 -0.0003 13 0 0 0 2.16E+07 2.21E+07 - - - 6.3258 0.9999 221125_WJC_METTL3_EV_vs_WT_F09.04008.04008.2 9.26E-05 16-Oct R.SDTSGHFQR.L sp|P50995|ANX11_HUMAN 1 1033.4577 0.93 125846 4008 2 1033.45854 517.7361 Annexin A11 OS=Homo sapiens OX=9606 GN=ANXA11 PE=1 SV=1 6.46 1370.7 - 421802 - - - 0.7925 - 2.131 0.534 - 665.7 1 2 0 0.0008 9 0 0 0 2.31E+06 2.48E+06 - - - 5.1737 1 221125_WJC_METTL3_EV_vs_WT_F09.04009.04009.2 6.51E-09 16/24 K.VSSAEGAAKEEPK.R "sp|P05114|HMGN1_HUMAN,tr|F2Z2W6|F2Z2W6_HUMAN,tr|F2Z2Y5|F2Z2Y5_HUMAN,tr|A6NEL0|A6NEL0_HUMAN,tr|H7BXJ5|H7BXJ5_HUMAN,tr|A0A494C035|A0A494C035_HUMAN" 6 1301.6463 0.98 125847 4009 2 1301.64701 651.8304 Non-histone chromosomal protein HMG-14 OS=Homo sapiens OX=9606 GN=HMGN1 PE=1 SV=3 4.79 1370.8 - 352248 - - - 0.5378 - 3.165 0.62 - 924.3 1 2 1 0.0007 13 0 0 0 2.16E+07 2.21E+07 - - - 6.5771 0.9999 221125_WJC_METTL3_EV_vs_WT_F09.04012.04012.2 4.20E-05 24-Sep R.AASQPPNSSEAGR.K "sp|Q9UI08|EVL_HUMAN,tr|H0YJN0|H0YJN0_HUMAN" 2 1270.5902 5.33 125850 4012 2 1270.58913 636.3024 Ena\VASP-like protein OS=Homo sapiens OX=9606 GN=EVL PE=1 SV=2 6.05 1371.2 - 266312 - - - -0.8358 - 1.706 0.648 - 156.9 1 2 0 -0.0011 13 0 0 0 2.70E+06 5.07E+05 - - - 5.1977 0.9999 221125_WJC_METTL3_EV_vs_WT_F09.04018.04018.3 4.19E-08 15/48 K.VSSAEGAAK[136.11]EEPK[136.11].R "sp|P05114|HMGN1_HUMAN,tr|F2Z2W6|F2Z2W6_HUMAN,tr|F2Z2Y5|F2Z2Y5_HUMAN,tr|A6NEL0|A6NEL0_HUMAN,tr|H7BXJ5|H7BXJ5_HUMAN,tr|A0A494C035|A0A494C035_HUMAN" 6 1317.6747 0.91 125854 4018 3 1317.671805 440.2322 Non-histone chromosomal protein HMG-14 OS=Homo sapiens OX=9606 GN=HMGN1 PE=1 SV=3 4.79 1372 - 2.74E+07 - - - -2.2046 - 3.196 0.586 - 351.7 1 2 1 -0.0029 13 0 0 0 2.06E+08 2.27E+08 - - - 8.2228 0.9999 221125_WJC_METTL3_EV_vs_WT_F09.04025.04025.3 0.0524 14/44 R.VLSTVHTHSSVK.S "sp|Q13155|AIMP2_HUMAN,tr|A8MU58|A8MU58_HUMAN" 2 1293.7041 1.29 125861 4025 3 1293.701543 432.242 Aminoacyl tRNA synthase complex-interacting multifunctional protein 2 OS=Homo sapiens OX=9606 GN=AIMP2 PE=1 SV=2 8.74 1372.5 - 1.32E+06 - - - -1.9765 - 2.686 0.432 - 310.5 1 2 0 -0.0026 12 0 0 0 1.23E+07 9.56E+06 - - - 6.0944 0.9995 221125_WJC_METTL3_EV_vs_WT_F09.04026.04026.2 0.00349 16-Dec R.K[136.11]SVLADQGK[136.11].S "sp|Q9NYF8|BCLF1_HUMAN,tr|E9PKI6|E9PKI6_HUMAN,tr|A0A1W2PQ43|A0A1W2PQ43_HUMAN,tr|E9PK91|E9PK91_HUMAN,tr|E9PK09|E9PK09_HUMAN,tr|E9PQN2|E9PQN2_HUMAN" 6 960.5575 2.58 125862 4026 2 960.554713 481.286 Bcl-2-associated transcription factor 1 OS=Homo sapiens OX=9606 GN=BCLAF1 PE=1 SV=2 8.59 1372.6 - 1.18E+06 - - - -2.8962 - 2.337 0.451 - 460.4 1 2 0 -0.0028 9 0 0 0 3.16E+07 1.23E+07 - - - 4.827 0.9892 221125_WJC_METTL3_EV_vs_WT_F09.04027.04027.2 4.33E-05 24-Nov E.VSSSGQEVQSSAK.E "sp|P35527|K1C9_HUMAN,tr|K7EQQ3|K7EQQ3_HUMAN" 2 1292.6208 0.55 125863 4027 2 1292.618448 647.3177 "Keratin, type I cytoskeletal 9 OS=Homo sapiens OX=9606 GN=KRT9 PE=1 SV=3" 5.97 1372.7 - 710702 - - - -1.8381 - 2.539 0.532 - 510.7 1 1 0 -0.0024 13 0 0 0 3.63E+06 6.55E+06 - - - 5.361 0.9983 221125_WJC_METTL3_EV_vs_WT_F09.04036.04036.2 0.00127 16-Sep R.KSVLADQGK.S "sp|Q9NYF8|BCLF1_HUMAN,tr|E9PKI6|E9PKI6_HUMAN,tr|A0A1W2PQ43|A0A1W2PQ43_HUMAN,tr|E9PK91|E9PK91_HUMAN,tr|E9PK09|E9PK09_HUMAN,tr|E9PQN2|E9PQN2_HUMAN" 6 944.5291 2.58 125870 4036 2 944.525187 473.2718 Bcl-2-associated transcription factor 1 OS=Homo sapiens OX=9606 GN=BCLAF1 PE=1 SV=2 8.59 1373.8 - 3.36E+06 - - - -4.1375 - 2.253 0.396 - 221.1 1 2 0 -0.0039 9 0 0 0 3.16E+07 1.23E+07 - - - 4.3145 0.9997 221125_WJC_METTL3_EV_vs_WT_F09.04044.04044.2 3.47E-06 16-Nov K.TFHHVYSGK[136.11].D sp|Q9NR30|DDX21_HUMAN 1 1082.5389 0.99 125876 4044 2 1082.536315 542.2767 Nucleolar RNA helicase 2 OS=Homo sapiens OX=9606 GN=DDX21 PE=1 SV=5 8.31 1374.8 - 944515 - - - -2.3685 - 2.058 0.572 - 538.1 1 2 0 -0.0026 9 0 0 0 1.59E+07 1.60E+07 - - - 5.353 1 221125_WJC_METTL3_EV_vs_WT_F09.04047.04047.2 3.01E-06 16-Nov K.TFHHVYSGK.D sp|Q9NR30|DDX21_HUMAN 1 1074.5247 1 125879 4047 2 1074.520043 538.2696 Nucleolar RNA helicase 2 OS=Homo sapiens OX=9606 GN=DDX21 PE=1 SV=5 8.31 1375 - 631650 - - - -4.3145 - 2.201 0.63 - 435.4 1 2 0 -0.0046 9 0 0 0 1.61E+07 1.61E+07 - - - 5.9751 0.9861 221125_WJC_METTL3_EV_vs_WT_F09.04052.04052.3 0.000974 Nov-44 R.VKDASPNQVAEK.V sp|O43402|EMC8_HUMAN 1 1284.6674 1.27 125882 4052 3 1284.661311 429.2297 ER membrane protein complex subunit 8 OS=Homo sapiens OX=9606 GN=EMC8 PE=1 SV=1 6.04 1375.6 - 989622 - - - -4.7242 - 2.131 0.341 - 121.7 1 2 1 -0.0061 12 0 0 0 3.59E+07 2.81E+07 - - - 4.4373 0.9999 221125_WJC_METTL3_EV_vs_WT_F09.04063.04063.3 0.000106 14/48 R.AIGSTSKPQESPK.G "sp|P18887|XRCC1_HUMAN,tr|M0QYS5|M0QYS5_HUMAN,tr|F5H8D7|F5H8D7_HUMAN" 3 1328.6936 1.04 125888 4063 3 1328.691134 443.9051 DNA repair protein XRCC1 OS=Homo sapiens OX=9606 GN=XRCC1 PE=1 SV=2 8.64 1377 - 1.84E+06 - - - -1.8522 - 2.531 0.419 - 187.7 1 2 0 -0.0025 13 0 0 0 2.82E+07 2.72E+07 - - - 5.7285 0.9542 221125_WJC_METTL3_EV_vs_WT_F09.04064.04064.2 0.00455 16-Jun S.DADYDYQNR.L "sp|P12259|FA5_HUMAN,tr|A0A0A0MRJ7|A0A0A0MRJ7_HUMAN" 2 1158.4578 284.39 125889 4064 2 1158.455527 580.2362 Coagulation factor V OS=Homo sapiens OX=9606 GN=F5 PE=1 SV=4 3.93 1377.2 - 998078 - - - -1.9457 - 1.283 0.479 - 171.1 1 1 0 -0.0023 9 0 0 0 1.08E+07 3.80E+04 - - - 3.2991 0.8263 221125_WJC_METTL3_EV_vs_WT_F09.04070.04070.3 1.5 Jul-36 K.QQKPTLSGQR.F "sp|Q7L1Q6|BZW1_HUMAN,tr|C9JFN4|C9JFN4_HUMAN,tr|C9JV57|C9JV57_HUMAN,tr|C9JWF5|C9JWF5_HUMAN,tr|C9J188|C9J188_HUMAN,tr|C9IZ80|C9IZ80_HUMAN" 6 1141.6204 0.79 125893 4070 3 1141.616723 381.5474 Basic leucine zipper and W2 domain-containing protein 1 OS=Homo sapiens OX=9606 GN=BZW1 PE=1 SV=1 11 1377.8 - 2.41E+06 - - - -3.1946 - 1.261 0.151 - 67.5 1 2 0 -0.0036 10 0 0 0 3.21E+07 4.09E+07 - - - 0.8998 0.9376 221125_WJC_METTL3_EV_vs_WT_F09.04071.04071.3 0.0642 Sep-44 R.VK[136.11]DASPNQVAEK[136.11].V sp|O43402|EMC8_HUMAN 1 1300.6958 1.27 125894 4071 3 1300.693791 434.5725 ER membrane protein complex subunit 8 OS=Homo sapiens OX=9606 GN=EMC8 PE=1 SV=1 6.04 1377.8 - 2.05E+06 - - - -1.5292 - 1.658 0.163 - 107.7 1 2 1 -0.002 12 0 0 0 3.59E+07 2.81E+07 - - - 1.7582 0.9966 221125_WJC_METTL3_EV_vs_WT_F09.04075.04075.3 0.0136 Oct-36 K.QQK[136.11]PTLSGQR[166.11].F "sp|Q7L1Q6|BZW1_HUMAN,tr|C9JFN4|C9JFN4_HUMAN,tr|C9JV57|C9JV57_HUMAN,tr|C9JWF5|C9JWF5_HUMAN,tr|C9J188|C9J188_HUMAN,tr|C9IZ80|C9IZ80_HUMAN" 6 1159.6428 0.79 125895 4075 3 1159.638638 387.5549 Basic leucine zipper and W2 domain-containing protein 1 OS=Homo sapiens OX=9606 GN=BZW1 PE=1 SV=1 11 1378.4 - 4.40E+06 - - - -3.6235 - 1.704 0.325 - 158.6 1 2 0 -0.0042 10 0 0 0 3.21E+07 4.09E+07 - - - 3.7188 0.9926 221125_WJC_METTL3_EV_vs_WT_F09.04076.04076.3 0.0462 Nov-48 R.AIGSTSK[136.11]PQESPK[136.11].G "sp|P18887|XRCC1_HUMAN,tr|M0QYS5|M0QYS5_HUMAN,tr|F5H8D7|F5H8D7_HUMAN" 3 1344.722 1.04 125896 4076 3 1344.717038 449.2479 DNA repair protein XRCC1 OS=Homo sapiens OX=9606 GN=XRCC1 PE=1 SV=2 8.64 1378.4 - 1.83E+06 - - - -3.6863 - 1.951 0.254 - 127.2 1 2 0 -0.005 13 0 0 0 2.82E+07 2.72E+07 - - - 3.1825 1 221125_WJC_METTL3_EV_vs_WT_F09.04078.04078.2 8.79E-08 14/22 K.GC[160.03]SEDHSGLDAK[136.11].S sp|Q5JSZ5|PRC2B_HUMAN 1 1282.5339 0.84 125898 4078 2 1282.529005 642.2742 Protein PRRC2B OS=Homo sapiens OX=9606 GN=PRRC2B PE=1 SV=2 4.54 1378.7 - 780517 - - - -3.8401 - 2.896 0.689 - 619.5 1 2 0 -0.0049 12 0 0 0 7.69E+06 9.20E+06 - - - 6.9262 1 221125_WJC_METTL3_EV_vs_WT_F09.04079.04079.2 7.74E-11 14/22 K.GC[160.03]SEDHSGLDAK.S sp|Q5JSZ5|PRC2B_HUMAN 1 1274.5197 0.84 125899 4079 2 1274.514986 638.2671 Protein PRRC2B OS=Homo sapiens OX=9606 GN=PRRC2B PE=1 SV=2 4.54 1378.8 - 652619 - - - -3.7222 - 3.082 0.723 - 654 1 2 0 -0.0047 12 0 0 0 7.69E+06 9.20E+06 - - - 7.3412 0.9998 221125_WJC_METTL3_EV_vs_WT_F09.04080.04080.2 2.28E-05 18-Jul K.GHEDDSYEAR.K "sp|Q9H2P0|ADNP_HUMAN,tr|A0A2R8Y6X0|A0A2R8Y6X0_HUMAN,tr|A0A669KBJ7|A0A669KBJ7_HUMAN" 3 1177.4636 0.98 125900 4080 2 1177.461875 589.7391 Activity-dependent neuroprotector homeobox protein OS=Homo sapiens OX=9606 GN=ADNP PE=1 SV=1 4.31 1379 - 502118 - - - -1.4608 - 1.639 0.631 - 185.4 1 2 0 -0.0017 10 0 0 0 4.16E+06 4.27E+06 - - - 5.0802 0.9244 221125_WJC_METTL3_EV_vs_WT_F09.04081.04081.2 0.0407 18-Jun K.QQKPTLSGQR.F "sp|Q7L1Q6|BZW1_HUMAN,tr|C9JFN4|C9JFN4_HUMAN,tr|C9JV57|C9JV57_HUMAN,tr|C9JWF5|C9JWF5_HUMAN,tr|C9J188|C9J188_HUMAN,tr|C9IZ80|C9IZ80_HUMAN" 6 1141.6204 0.76 125901 4081 2 1141.615806 571.8175 Basic leucine zipper and W2 domain-containing protein 1 OS=Homo sapiens OX=9606 GN=BZW1 PE=1 SV=1 11 1379.1 - 471825 - - - -3.9978 - 1.144 0.194 - 104.9 2 2 0 -0.0046 10 0 0 0 3.16E+06 4.18E+06 - - - 0.7135 0.9974 221125_WJC_METTL3_EV_vs_WT_F09.04087.04087.3 0.00353 Aug-36 K.NK[136.11]EEAAEYAK[136.11].L "sp|P62753|RS6_HUMAN,tr|A2A3R5|A2A3R5_HUMAN" 2 1167.5743 1.23 125905 4087 3 1167.572749 390.1987 40S ribosomal protein S6 OS=Homo sapiens OX=9606 GN=RPS6 PE=1 SV=1 4.79 1379.8 - 2.23E+06 - - - -1.301 - 1.728 0.331 - 150.1 1 2 1 -0.0015 10 0 0 0 1.50E+07 1.22E+07 - - - 3.8273 1 221125_WJC_METTL3_EV_vs_WT_F09.04088.04088.3 6.64E-09 Oct-36 K.GHEDDSYEAR.K "sp|Q9H2P0|ADNP_HUMAN,tr|A0A2R8Y6X0|A0A2R8Y6X0_HUMAN,tr|A0A669KBJ7|A0A669KBJ7_HUMAN" 3 1177.4636 1.16 125906 4088 3 1177.461019 393.4951 Activity-dependent neuroprotector homeobox protein OS=Homo sapiens OX=9606 GN=ADNP PE=1 SV=1 4.31 1379.8 - 1.30E+06 - - - -2.1878 - 2.231 0.703 - 168.8 1 2 0 -0.0026 10 0 0 0 1.41E+07 1.22E+07 - - - 8.7205 0.9931 221125_WJC_METTL3_EV_vs_WT_F09.04091.04091.2 1.39 18-Sep K.NK[136.11]EEAAEYAK[136.11].L "sp|P62753|RS6_HUMAN,tr|A2A3R5|A2A3R5_HUMAN" 2 1167.5743 1.29 125909 4091 2 1167.572797 584.7944 40S ribosomal protein S6 OS=Homo sapiens OX=9606 GN=RPS6 PE=1 SV=1 4.79 1380.2 - 761858 - - - -1.2599 - 1.919 0.306 - 270.5 1 2 1 -0.0015 10 0 0 0 7.12E+06 5.52E+06 - - - 3.12 0.9856 221125_WJC_METTL3_EV_vs_WT_F09.04096.04096.2 0.018 22-Jul K.NEPQNPGANSAR.G sp|P20339|RAB5A_HUMAN 1 1253.5749 1.09 125914 4096 2 1253.570701 627.7947 Ras-related protein Rab-5A OS=Homo sapiens OX=9606 GN=RAB5A PE=1 SV=2 6 1380.8 - 306969 - - - -3.3305 - 1.209 0.279 - 130.3 1 2 0 -0.0042 12 0 0 0 4.99E+06 4.58E+06 - - - 1.5998 0.9989 221125_WJC_METTL3_EV_vs_WT_F09.04105.04105.2 7.66E-06 13/18 K.NKEEAAEYAK.L "sp|P62753|RS6_HUMAN,tr|A2A3R5|A2A3R5_HUMAN" 2 1151.5459 1.29 125921 4105 2 1151.545565 576.7802 40S ribosomal protein S6 OS=Homo sapiens OX=9606 GN=RPS6 PE=1 SV=1 4.79 1381.7 - 844223 - - - -0.2631 - 2.127 0.57 - 570.2 1 2 1 -0.0003 10 0 0 0 7.12E+06 5.52E+06 - - - 5.3576 0.9999 221125_WJC_METTL3_EV_vs_WT_F09.04107.04107.3 0.000148 Aug-36 R.VQHSC[160.03]PIC[160.03]QK[136.11].K "sp|Q9NSC2|SALL1_HUMAN,sp|Q9BXA9|SALL3_HUMAN,tr|A0A087WXW6|A0A087WXW6_HUMAN,tr|A0A140TA74|A0A140TA74_HUMAN,tr|A0A140TA70|A0A140TA70_HUMAN,tr|H3BSM9|H3BSM9_HUMAN,tr|A9JR48|A9JR48_HUMAN" 7 1263.5944 1.86 125923 4107 3 1263.594115 422.2054 Sal-like protein 1 OS=Homo sapiens OX=9606 GN=SALL1 PE=1 SV=2 8.04 1382 - 638498 - - - -0.1955 - 1.84 0.406 - 116.2 1 2 0 -0.0002 10 0 0 0 2.39E+07 1.28E+07 - - - 4.8472 0.9997 221125_WJC_METTL3_EV_vs_WT_F09.04108.04108.2 0.00107 14/18 R.RAEENALQQK.A sp|P15924|DESP_HUMAN 1 1185.6102 23.87 125924 4108 2 1185.608354 593.8124 Desmoplakin OS=Homo sapiens OX=9606 GN=DSP PE=1 SV=3 6.14 1382.1 - 569541 - - - -1.5562 - 2.305 0.402 - 765.8 1 2 0 -0.0018 10 0 0 0 2.89E+07 1.21E+06 - - - 4.3406 0.8254 221125_WJC_METTL3_EV_vs_WT_F09.04114.04114.2 1.37 22-Mar K.GNSPPSSGEAC[160.03]R[166.11].E sp|P41227|NAA10_HUMAN 1 1227.5178 0.52 125930 4114 2 1227.518526 614.7662 N-alpha-acetyltransferase 10 OS=Homo sapiens OX=9606 GN=NAA10 PE=1 SV=1 5.99 1382.9 - 71372.2 - - - 0.6167 - 0.635 0.145 - 23.1 2 2 0 0.0008 12 0 0 0 2.92E+06 5.66E+06 - - - -1.2176 0.9999 221125_WJC_METTL3_EV_vs_WT_F09.04122.04122.3 1.11E-05 Nov-36 K.STETAQQLK[136.11]R[166.11].S "sp|Q9H3P2|NELFA_HUMAN,tr|C9JHL4|C9JHL4_HUMAN,tr|H7C0W2|H7C0W2_HUMAN,tr|C9JEM7|C9JEM7_HUMAN,tr|H0Y3X6|H0Y3X6_HUMAN,tr|H7C2C7|H7C2C7_HUMAN,tr|A0A0C4DFX9|A0A0C4DFX9_HUMAN" 7 1178.6374 0.45 125936 4122 3 1178.637347 393.8864 Negative elongation factor A OS=Homo sapiens OX=9606 GN=NELFA PE=1 SV=3 8.46 1383.8 - 565708 - - - -0.0619 - 2.45 0.411 - 264.1 1 2 0 -0.0001 10 0 0 0 1.39E+06 3.09E+06 - - - 5.7392 0.9987 221125_WJC_METTL3_EV_vs_WT_F09.04123.04123.2 0.0178 14-Jul K.K[136.11]C[160.03]SESIPK[136.11].D "sp|P09874|PARP1_HUMAN,tr|A0A7I2V384|A0A7I2V384_HUMAN,tr|A0A7I2V5E9|A0A7I2V5E9_HUMAN,tr|A0A7I2V625|A0A7I2V625_HUMAN,tr|A0A7I2V3E1|A0A7I2V3E1_HUMAN" 5 963.503 1.1 125937 4123 2 963.502871 482.7588 Poly [ADP-ribose] polymerase 1 OS=Homo sapiens OX=9606 GN=PARP1 PE=1 SV=4 8.2 1383.9 - 519976 - - - -0.1515 - 1.534 0.243 - 202.1 1 2 0 -0.0001 8 0 0 0 3.62E+06 3.28E+06 - - - 2.1262 0.8144 221125_WJC_METTL3_EV_vs_WT_F09.04125.04125.2 0.603 14-Jun R.TYSC[160.03]IHC[160.03]R.A "sp|O60688|YPEL1_HUMAN,sp|Q96QA6|YPEL2_HUMAN,tr|A0A5F9ZH55|A0A5F9ZH55_HUMAN,tr|B5MCX2|B5MCX2_HUMAN,tr|A0A5F9ZHD1|A0A5F9ZHD1_HUMAN" 5 1095.459 8.19 125939 4125 2 1095.463821 548.7368 Protein yippee-like 1 OS=Homo sapiens OX=9606 GN=YPEL1 PE=3 SV=1 7.77 1384.2 - 265473 - - - 4.4155 - 0.85 0.231 - 60.9 1 2 0 0.0048 8 0 0 0 2.81E+06 3.43E+05 - - - 0.2555 0.9976 221125_WJC_METTL3_EV_vs_WT_F09.04126.04126.2 0.043 18-Nov K.NSQGEEVAQR.S sp|P20700|LMNB1_HUMAN 1 1116.516 1.38 125940 4126 2 1116.51106 559.2653 Lamin-B1 OS=Homo sapiens OX=9606 GN=LMNB1 PE=1 SV=2 4.53 1384.3 - 186496 - - - -4.3922 - 2.185 0.392 - 550.8 1 2 0 -0.0049 10 0 0 0 2.55E+06 1.85E+06 - - - 4.1165 0.9997 221125_WJC_METTL3_EV_vs_WT_F09.04127.04127.2 0.00276 18-Oct K.NSQGEEVAQR[166.11].S sp|P20700|LMNB1_HUMAN 1 1126.5242 1.53 125941 4127 2 1126.52398 564.2694 Lamin-B1 OS=Homo sapiens OX=9606 GN=LMNB1 PE=1 SV=2 4.53 1384.4 - 177243 - - - -0.2255 - 1.978 0.353 - 485.7 1 2 0 -0.0003 10 0 0 0 2.83E+06 1.85E+06 - - - 3.5521 0.9993 221125_WJC_METTL3_EV_vs_WT_F09.04134.04134.3 0.0226 Sep-36 R.VQHSC[160.03]PIC[160.03]QK.K "sp|Q9NSC2|SALL1_HUMAN,sp|Q9BXA9|SALL3_HUMAN,tr|A0A087WXW6|A0A087WXW6_HUMAN,tr|A0A140TA74|A0A140TA74_HUMAN,tr|A0A140TA70|A0A140TA70_HUMAN,tr|H3BSM9|H3BSM9_HUMAN,tr|A9JR48|A9JR48_HUMAN" 7 1255.5802 2.02 125946 4134 3 1255.57949 419.534 Sal-like protein 1 OS=Homo sapiens OX=9606 GN=SALL1 PE=1 SV=2 8.04 1385.4 - 2.33E+06 - - - -0.5352 - 1.599 0.331 - 88.4 1 2 0 -0.0007 10 0 0 0 2.39E+07 1.19E+07 - - - 3.6009 0.9588 221125_WJC_METTL3_EV_vs_WT_F09.04139.04139.2 3.04 14-Apr K.KC[160.03]SESIPK.D "sp|P09874|PARP1_HUMAN,tr|A0A7I2V384|A0A7I2V384_HUMAN,tr|A0A7I2V5E9|A0A7I2V5E9_HUMAN,tr|A0A7I2V625|A0A7I2V625_HUMAN,tr|A0A7I2V3E1|A0A7I2V3E1_HUMAN" 5 947.4746 1.1 125951 4139 2 947.474446 474.7446 Poly [ADP-ribose] polymerase 1 OS=Homo sapiens OX=9606 GN=PARP1 PE=1 SV=4 8.2 1385.9 - 554639 - - - -0.1805 - 1.133 0.065 - 85 3 2 0 -0.0002 8 0 0 0 3.62E+06 3.28E+06 - - - -0.3155 0.9996 221125_WJC_METTL3_EV_vs_WT_F09.04143.04143.3 0.00366 Oct-36 K.STETAQQLKR.S "sp|Q9H3P2|NELFA_HUMAN,tr|C9JHL4|C9JHL4_HUMAN,tr|H7C0W2|H7C0W2_HUMAN,tr|C9JEM7|C9JEM7_HUMAN,tr|H0Y3X6|H0Y3X6_HUMAN,tr|H7C2C7|H7C2C7_HUMAN,tr|A0A0C4DFX9|A0A0C4DFX9_HUMAN" 7 1160.6149 0.36 125955 4143 3 1160.614302 387.8789 Negative elongation factor A OS=Homo sapiens OX=9606 GN=NELFA PE=1 SV=3 8.46 1386.4 - 424424 - - - -0.5583 - 2.014 0.3 - 210.8 1 2 0 -0.0006 10 0 0 0 1.48E+06 4.10E+06 - - - 3.9292 0.9976 221125_WJC_METTL3_EV_vs_WT_F09.04144.04144.2 0.0505 20-Aug K.NSTPSEPGSGR.G sp|P51858|HDGF_HUMAN 1 1087.4894 0.69 125956 4144 2 1087.485787 544.752 Hepatoma-derived growth factor OS=Homo sapiens OX=9606 GN=HDGF PE=1 SV=1 6 1386.6 - 378974 - - - -3.3361 - 1.681 0.374 - 185.5 1 2 0 -0.0036 11 0 0 0 4.55E+06 6.58E+06 - - - 3.2073 0.9997 221125_WJC_METTL3_EV_vs_WT_F09.04148.04148.2 3.04E-08 26-Sep K.ATSTSTSGAGDVGK[136.11].E sp|Q96T17|MA7D2_HUMAN 1 1245.5928 1.64 125960 4148 2 1245.595503 623.8037 MAP7 domain-containing protein 2 OS=Homo sapiens OX=9606 GN=MAP7D2 PE=1 SV=2 5.88 1387.1 - 256741 - - - 2.1508 - 2.068 0.555 - 252.1 1 2 0 0.0027 14 0 0 0 2.52E+06 1.54E+06 - - - 4.9627 0.9994 221125_WJC_METTL3_EV_vs_WT_F09.04152.04152.2 1.16E-07 26-Sep K.ATSTSTSGAGDVGK.E sp|Q96T17|MA7D2_HUMAN 1 1237.5786 0.92 125963 4152 2 1237.582799 619.7966 MAP7 domain-containing protein 2 OS=Homo sapiens OX=9606 GN=MAP7D2 PE=1 SV=2 5.88 1387.6 - 174152 - - - 3.3735 - 1.979 0.6 - 212.2 1 2 0 0.0042 14 0 0 0 1.41E+06 1.54E+06 - - - 5.1842 0.9999 221125_WJC_METTL3_EV_vs_WT_F09.04155.04155.2 2.33E-05 16-Dec R.HQGTFTDEK.S sp|Q92922|SMRC1_HUMAN 1 1061.4778 2.83 125966 4155 2 1061.477657 531.7462 SWI\SNF complex subunit SMARCC1 OS=Homo sapiens OX=9606 GN=SMARCC1 PE=1 SV=3 5.32 1387.8 - 1.09E+06 - - - -0.1234 - 2.292 0.544 - 383.8 1 2 0 -0.0001 9 0 0 0 6.88E+06 2.43E+06 - - - 5.4585 1 221125_WJC_METTL3_EV_vs_WT_F09.04157.04157.2 5.35E-11 17/30 K.SAAQAAAQTNSNAAGK.Q sp|Q8NC51|PAIRB_HUMAN 1 1459.7015 0.82 125968 4157 2 1459.701522 730.858 Plasminogen activator inhibitor 1 RNA-binding protein OS=Homo sapiens OX=9606 GN=SERBP1 PE=1 SV=2 8.47 1388 - 537685 - - - -0.0082 - 3.433 0.687 - 1122.5 1 2 0 0 16 0 0 0 7.37E+07 8.97E+07 - - - 7.1476 0.9997 221125_WJC_METTL3_EV_vs_WT_F09.04158.04158.2 0.00478 16-Aug R.HQGTFTDEK[136.11].S sp|Q92922|SMRC1_HUMAN 1 1069.492 2.83 125969 4158 2 1069.491114 535.7533 SWI\SNF complex subunit SMARCC1 OS=Homo sapiens OX=9606 GN=SMARCC1 PE=1 SV=3 5.32 1388.2 - 493522 - - - -0.8172 - 1.815 0.381 - 146.5 1 2 0 -0.0009 9 0 0 0 6.88E+06 2.43E+06 - - - 3.5793 1 221125_WJC_METTL3_EV_vs_WT_F09.04165.04165.3 1.63E-07 15/60 K.SAAQAAAQTNSNAAGK.Q sp|Q8NC51|PAIRB_HUMAN 1 1459.7015 0.89 125974 4165 3 1459.701794 487.5745 Plasminogen activator inhibitor 1 RNA-binding protein OS=Homo sapiens OX=9606 GN=SERBP1 PE=1 SV=2 8.47 1389.1 - 1.56E+06 - - - 0.1781 - 2.531 0.583 - 331.1 1 2 0 0.0003 16 0 0 0 4.89E+07 5.52E+07 - - - 7.4225 0.9998 221125_WJC_METTL3_EV_vs_WT_F09.04169.04169.2 0.00815 20-Sep R.GQTQEEEVRPK.G "sp|O15234|CASC3_HUMAN,tr|J3KSY7|J3KSY7_HUMAN" 2 1299.6419 1.96 125977 4169 2 1299.642613 650.8282 Protein CASC3 OS=Homo sapiens OX=9606 GN=CASC3 PE=1 SV=2 4.79 1389.6 - 176523 - - - 0.554 - 1.967 0.491 - 212.2 1 2 0 0.0007 11 0 0 0 1.78E+06 9.11E+05 - - - 4.4974 0.9996 221125_WJC_METTL3_EV_vs_WT_F09.04177.04177.3 0.00471 Dec-44 K.EGESVQGSHVTR.W sp|Q92503|S14L1_HUMAN 1 1284.6058 1.4 125984 4177 3 1284.604392 429.2092 SEC14-like protein 1 OS=Homo sapiens OX=9606 GN=SEC14L1 PE=1 SV=2 5.4 1390.6 - 580010 - - - -1.1288 - 1.481 0.394 - 170.4 1 2 0 -0.0014 12 0 0 0 6.72E+06 4.80E+06 - - - 4.0209 0.9995 221125_WJC_METTL3_EV_vs_WT_F09.04184.04184.3 0.00628 Nov-36 R.GSQFTSK[136.11]EER[166.11].D sp|Q9UQE7|SMC3_HUMAN 1 1185.5745 0.76 125989 4184 3 1185.574456 396.1988 Structural maintenance of chromosomes protein 3 OS=Homo sapiens OX=9606 GN=SMC3 PE=1 SV=2 6.14 1391.5 - 978262 - - - -0.0253 - 2.431 0.358 - 261.2 1 2 1 0 10 0 0 0 6.65E+06 8.76E+06 - - - 5.1256 0.9999 221125_WJC_METTL3_EV_vs_WT_F09.04185.04185.3 0.00491 16/36 R.R[166.11]LAPSPAR[166.11]PR[166.11].H "sp|O14654|IRS4_HUMAN,tr|A0A804CF45|A0A804CF45_HUMAN" 2 1149.6873 0.001 125990 4185 3 1149.687035 384.2364 Insulin receptor substrate 4 OS=Homo sapiens OX=9606 GN=IRS4 PE=1 SV=1 12.3 1391.6 - 681847 - - - -0.2479 - 2.627 0.359 - 233.5 1 2 0 -0.0003 10 0 0 0 0.00E+00 1.14E+07 - - - 5.3631 0.9996 221125_WJC_METTL3_EV_vs_WT_F09.04186.04186.2 0.000644 22-Jul K.NEPQNPGANSAR[166.11].G sp|P20339|RAB5A_HUMAN 1 1263.5831 1.44 125991 4186 2 1263.581977 632.7988 Ras-related protein Rab-5A OS=Homo sapiens OX=9606 GN=RAB5A PE=1 SV=2 6 1391.8 - 230059 - - - -0.9251 - 1.639 0.405 - 152.1 1 2 0 -0.0012 12 0 0 0 4.85E+06 3.37E+06 - - - 3.332 0.9621 221125_WJC_METTL3_EV_vs_WT_F09.04187.04187.2 0.00355 16-Jun A.SDSHRPEVK.L "sp|Q9NYF8|BCLF1_HUMAN,tr|E9PKI6|E9PKI6_HUMAN,tr|A0A1W2PQ43|A0A1W2PQ43_HUMAN,tr|E9PK91|E9PK91_HUMAN,tr|E9PJA7|E9PJA7_HUMAN,tr|E9PK09|E9PK09_HUMAN,tr|E9PQN2|E9PQN2_HUMAN" 7 1053.5203 2.56 125992 4187 2 1053.51852 527.7674 Bcl-2-associated transcription factor 1 OS=Homo sapiens OX=9606 GN=BCLAF1 PE=1 SV=2 6.47 1391.9 - 105138 - - - -1.7105 - 1.471 0.431 - 134.5 1 1 0 -0.0018 9 0 0 0 7.78E+06 3.04E+06 - - - 3.3404 1 221125_WJC_METTL3_EV_vs_WT_F09.04191.04191.2 5.49E-11 18/30 K.SAAQAAAQTNSNAAGK[136.11].Q sp|Q8NC51|PAIRB_HUMAN 1 1467.7157 0.82 125994 4191 2 1467.714104 734.8651 Plasminogen activator inhibitor 1 RNA-binding protein OS=Homo sapiens OX=9606 GN=SERBP1 PE=1 SV=2 8.47 1392.4 - 7.91E+06 - - - -1.1106 - 3.47 0.699 - 1336.9 1 2 0 -0.0016 16 0 0 0 7.37E+07 8.97E+07 - - - 7.2621 1 221125_WJC_METTL3_EV_vs_WT_F09.04195.04195.3 4.76E-05 13/36 K.QQTTVPQK[136.11]PR[166.11].Q "sp|Q9BY77|PDIP3_HUMAN,tr|F6VRR5|F6VRR5_HUMAN,tr|F8WCX5|F8WCX5_HUMAN,tr|Q6R954|Q6R954_HUMAN,tr|Q8WUT1|Q8WUT1_HUMAN,tr|F8WEE2|F8WEE2_HUMAN" 6 1199.6741 1.4 125998 4195 3 1199.673134 400.8987 Polymerase delta-interacting protein 3 OS=Homo sapiens OX=9606 GN=POLDIP3 PE=1 SV=2 11 1392.8 - 680030 - - - -0.8386 - 2.305 0.443 - 326.6 1 2 0 -0.001 10 0 0 0 2.58E+07 1.84E+07 - - - 5.9175 1 221125_WJC_METTL3_EV_vs_WT_F09.04202.04202.3 2.04E-09 15/60 K.SAAQAAAQTNSNAAGK[136.11].Q sp|Q8NC51|PAIRB_HUMAN 1 1467.7157 0.89 126003 4202 3 1467.712549 490.2459 Plasminogen activator inhibitor 1 RNA-binding protein OS=Homo sapiens OX=9606 GN=SERBP1 PE=1 SV=2 8.47 1393.7 - 4.46E+06 - - - -2.17 - 3.055 0.614 - 299.2 1 2 0 -0.0032 16 0 0 0 4.89E+07 5.52E+07 - - - 8.2501 0.9996 221125_WJC_METTL3_EV_vs_WT_F09.04206.04206.2 2.09E-05 26-Dec R.GSGGGSSGGSIGGR.G sp|P04264|K2C1_HUMAN 1 1091.4956 39.42 126007 4206 2 1091.498326 546.7551 "Keratin, type II cytoskeletal 1 OS=Homo sapiens OX=9606 GN=KRT1 PE=1 SV=6" 9.75 1394.1 - 156817 - - - 2.5314 - 2.426 0.513 - 409.3 1 2 0 0.0028 14 0 0 0 6.36E+06 1.61E+05 - - - 5.0531 0.9929 221125_WJC_METTL3_EV_vs_WT_F09.04207.04207.2 0.13 16-Jun R.K[136.11]NELETENR[166.11].L "sp|Q86VS8|HOOK3_HUMAN,tr|H0YE69|H0YE69_HUMAN" 2 1149.5745 4.31 126008 4207 2 1149.571953 575.7945 Protein Hook homolog 3 OS=Homo sapiens OX=9606 GN=HOOK3 PE=1 SV=2 4.79 1394.2 - 149039 - - - -2.2034 - 1.61 0.149 - 110.4 1 2 0 -0.0025 9 0 0 0 5.02E+06 1.17E+06 - - - 1.5185 0.9988 221125_WJC_METTL3_EV_vs_WT_F09.04209.04209.2 0.138 18-May K.QQTTVPQK[136.11]PR[166.11].Q "sp|Q9BY77|PDIP3_HUMAN,tr|F6VRR5|F6VRR5_HUMAN,tr|F8WCX5|F8WCX5_HUMAN,tr|Q6R954|Q6R954_HUMAN,tr|Q8WUT1|Q8WUT1_HUMAN,tr|F8WEE2|F8WEE2_HUMAN" 6 1199.6741 1.12 126010 4209 2 1199.67393 600.8443 Polymerase delta-interacting protein 3 OS=Homo sapiens OX=9606 GN=POLDIP3 PE=1 SV=2 11 1394.5 - 94448.4 - - - -0.175 - 1.242 0.345 - 60.6 1 2 0 -0.0002 10 0 0 0 1.09E+06 9.73E+05 - - - 2.194 1 221125_WJC_METTL3_EV_vs_WT_F09.04215.04215.3 1.64E-05 13/48 K.ISHLSGSGSGDER[166.11].V "sp|Q96T37|RBM15_HUMAN,tr|A0A494C001|A0A494C001_HUMAN,tr|A0A499FJY3|A0A499FJY3_HUMAN,tr|A0A087WWP4|A0A087WWP4_HUMAN" 4 1310.609 1.1 126014 4215 3 1310.60842 437.877 RNA-binding protein 15 OS=Homo sapiens OX=9606 GN=RBM15 PE=1 SV=2 5.32 1395.2 - 951927 - - - -0.4631 - 2.405 0.484 - 223.8 1 2 0 -0.0006 13 0 0 0 4.20E+07 3.82E+07 - - - 6.3152 0.9999 221125_WJC_METTL3_EV_vs_WT_F09.04216.04216.3 4.86E-06 15/48 K.ISHLSGSGSGDER.V "sp|Q96T37|RBM15_HUMAN,tr|A0A494C001|A0A494C001_HUMAN,tr|A0A499FJY3|A0A499FJY3_HUMAN,tr|A0A087WWP4|A0A087WWP4_HUMAN" 4 1300.6008 1.08 126015 4216 3 1300.601 434.5409 RNA-binding protein 15 OS=Homo sapiens OX=9606 GN=RBM15 PE=1 SV=2 5.32 1395.3 - 617612 - - - 0.1868 - 2.448 0.419 - 259.1 1 2 0 0.0002 13 0 0 0 4.21E+07 3.88E+07 - - - 5.6387 0.9994 221125_WJC_METTL3_EV_vs_WT_F09.04217.04217.2 0.000583 16-Oct R.RGFSANSAR.L "sp|P48668|K2C6C_HUMAN,sp|P04259|K2C6B_HUMAN,sp|P02538|K2C6A_HUMAN" 3 964.4839 61.55 126016 4217 2 964.483431 483.2492 "Keratin, type II cytoskeletal 6C OS=Homo sapiens OX=9606 GN=KRT6C PE=1 SV=3" 12 1395.4 - 543336 - - - -0.4614 - 1.687 0.322 - 171.3 1 2 0 -0.0004 9 0 0 0 3.35E+07 5.44E+05 - - - 2.9321 0.9996 221125_WJC_METTL3_EV_vs_WT_F09.04219.04219.2 0.077 16-Jul R.RGDDSFGDK.Y "sp|P23588|IF4B_HUMAN,tr|E7EX17|E7EX17_HUMAN" 2 995.4308 3.86 126018 4219 2 995.429815 498.7227 Eukaryotic translation initiation factor 4B OS=Homo sapiens OX=9606 GN=EIF4B PE=1 SV=2 4.43 1395.7 - 338379 - - - -1.0277 - 1.74 0.381 - 220.7 1 2 0 -0.001 9 0 0 0 5.09E+06 1.32E+06 - - - 3.4572 0.9997 221125_WJC_METTL3_EV_vs_WT_F09.04220.04220.2 1.18E-05 20-Nov R.ASQQQQTNSIR[166.11].N "sp|O60934|NBN_HUMAN,tr|A0A0C4DG07|A0A0C4DG07_HUMAN" 2 1269.6301 1.32 126019 4220 2 1269.632801 635.8223 Nibrin OS=Homo sapiens OX=9606 GN=NBN PE=1 SV=1 9.79 1395.8 - 267731 - - - 2.1298 - 2.179 0.477 - 561.4 1 2 0 0.0027 11 0 0 0 8.94E+06 6.75E+06 - - - 4.6703 0.9886 221125_WJC_METTL3_EV_vs_WT_F09.04221.04221.2 0.00338 18-Sep L.ASDSHRPEVK.L "sp|Q9NYF8|BCLF1_HUMAN,tr|E9PKI6|E9PKI6_HUMAN,tr|A0A1W2PQ43|A0A1W2PQ43_HUMAN,tr|E9PK91|E9PK91_HUMAN,tr|E9PJA7|E9PJA7_HUMAN,tr|E9PK09|E9PK09_HUMAN,tr|E9PQN2|E9PQN2_HUMAN" 7 1124.5574 2.18 126020 4221 2 1124.557342 563.286 Bcl-2-associated transcription factor 1 OS=Homo sapiens OX=9606 GN=BCLAF1 PE=1 SV=2 6.8 1396 - 242180 - - - -0.0827 - 2.077 0.413 - 261.8 1 1 0 -0.0001 10 0 0 0 9.84E+06 4.52E+06 - - - 4.1316 0.9997 221125_WJC_METTL3_EV_vs_WT_F09.04225.04225.2 0.0146 18-Sep K.QQTTVPQKPR.Q "sp|Q9BY77|PDIP3_HUMAN,tr|F6VRR5|F6VRR5_HUMAN,tr|F8WCX5|F8WCX5_HUMAN,tr|Q6R954|Q6R954_HUMAN,tr|Q8WUT1|Q8WUT1_HUMAN,tr|F8WEE2|F8WEE2_HUMAN" 6 1181.6517 1.12 126024 4225 2 1181.651716 591.8331 Polymerase delta-interacting protein 3 OS=Homo sapiens OX=9606 GN=POLDIP3 PE=1 SV=2 11 1396.5 - 139169 - - - 0.0389 - 1.805 0.376 - 267.6 1 2 0 0 10 0 0 0 1.09E+06 9.73E+05 - - - 3.4666 0.9995 221125_WJC_METTL3_EV_vs_WT_F09.04226.04226.2 0.000459 24-Aug K.ISHLSGSGSGDER[166.11].V "sp|Q96T37|RBM15_HUMAN,tr|A0A494C001|A0A494C001_HUMAN,tr|A0A499FJY3|A0A499FJY3_HUMAN,tr|A0A087WWP4|A0A087WWP4_HUMAN" 4 1310.609 1.1 126025 4226 2 1310.606426 656.3118 RNA-binding protein 15 OS=Homo sapiens OX=9606 GN=RBM15 PE=1 SV=2 5.32 1396.6 - 57751.3 - - - -1.9846 - 1.662 0.465 - 231.9 1 2 0 -0.0026 13 0 0 0 4.29E+06 3.89E+06 - - - 3.7785 0.9988 221125_WJC_METTL3_EV_vs_WT_F09.04229.04229.2 0.0389 16-Aug R.KNELETENR.L "sp|Q86VS8|HOOK3_HUMAN,tr|H0YE69|H0YE69_HUMAN" 2 1131.552 3.89 126027 4229 2 1131.552636 566.7833 Protein Hook homolog 3 OS=Homo sapiens OX=9606 GN=HOOK3 PE=1 SV=2 4.79 1397 - 346935 - - - 0.5479 - 1.782 0.215 - 245 1 2 0 0.0006 9 0 0 0 5.02E+06 1.29E+06 - - - 2.3002 0.9999 221125_WJC_METTL3_EV_vs_WT_F09.04235.04235.2 0.000124 20-Nov R.ASQQQQTNSIR.N "sp|O60934|NBN_HUMAN,tr|A0A0C4DG07|A0A0C4DG07_HUMAN" 2 1259.6218 1.33 126032 4235 2 1259.621207 630.8182 Nibrin OS=Homo sapiens OX=9606 GN=NBN PE=1 SV=1 9.79 1397.6 - 811054 - - - -0.4922 - 2.446 0.479 - 499.5 1 2 0 -0.0006 11 0 0 0 8.97E+06 6.75E+06 - - - 4.9984 0.9998 221125_WJC_METTL3_EV_vs_WT_F09.04237.04237.2 0.000328 24-Oct K.ISHLSGSGSGDER.V "sp|Q96T37|RBM15_HUMAN,tr|A0A494C001|A0A494C001_HUMAN,tr|A0A499FJY3|A0A499FJY3_HUMAN,tr|A0A087WWP4|A0A087WWP4_HUMAN" 4 1300.6008 1.1 126034 4237 2 1300.600503 651.3077 RNA-binding protein 15 OS=Homo sapiens OX=9606 GN=RBM15 PE=1 SV=2 5.32 1397.9 - 332919 - - - -0.1953 - 2.163 0.435 - 350.3 1 2 0 -0.0003 13 0 0 0 4.29E+06 3.89E+06 - - - 4.2339 0.9773 221125_WJC_METTL3_EV_vs_WT_F09.04238.04238.2 0.000175 18-Sep L.ASDSHR[166.11]PEVK[136.11].L "sp|Q9NYF8|BCLF1_HUMAN,tr|E9PKI6|E9PKI6_HUMAN,tr|A0A1W2PQ43|A0A1W2PQ43_HUMAN,tr|E9PK91|E9PK91_HUMAN,tr|E9PJA7|E9PJA7_HUMAN,tr|E9PK09|E9PK09_HUMAN,tr|E9PQN2|E9PQN2_HUMAN" 7 1142.5799 2.18 126035 4238 2 1142.577881 572.2972 Bcl-2-associated transcription factor 1 OS=Homo sapiens OX=9606 GN=BCLAF1 PE=1 SV=2 6.8 1398 - 228413 - - - -1.7714 - 1.799 0.452 - 260.8 1 1 0 -0.002 10 0 0 0 9.84E+06 4.52E+06 - - - 4.018 0.8742 221125_WJC_METTL3_EV_vs_WT_F09.04251.04251.2 0.00258 20-Jul M.IASDSHRPEVK.L "sp|Q9NYF8|BCLF1_HUMAN,tr|E9PKI6|E9PKI6_HUMAN,tr|A0A1W2PQ43|A0A1W2PQ43_HUMAN,tr|E9PK91|E9PK91_HUMAN,tr|E9PJA7|E9PJA7_HUMAN,tr|E9PK09|E9PK09_HUMAN,tr|E9PQN2|E9PQN2_HUMAN" 7 1237.6415 1.03 126046 4251 2 1237.645239 619.828 Bcl-2-associated transcription factor 1 OS=Homo sapiens OX=9606 GN=BCLAF1 PE=1 SV=2 6.75 1399.7 - 70781.6 - - - 3.0219 - 1.683 0.345 - 142.9 1 1 0 0.0037 11 0 0 0 6.99E+05 6.81E+05 - - - 2.9963 0.9947 221125_WJC_METTL3_EV_vs_WT_F09.04254.04254.3 0.0627 Dec-40 R.NLEGANQHVSK.E "sp|Q86XP3|DDX42_HUMAN,tr|A0A0A0MSJ0|A0A0A0MSJ0_HUMAN" 2 1195.5945 0.7 126047 4254 3 1195.592913 399.5388 ATP-dependent RNA helicase DDX42 OS=Homo sapiens OX=9606 GN=DDX42 PE=1 SV=1 6.75 1400.1 - 879277 - - - -1.3684 - 2.032 0.158 - 199 1 2 0 -0.0016 11 0 0 0 1.20E+07 1.72E+07 - - - 2.3153 0.8528 221125_WJC_METTL3_EV_vs_WT_F09.04255.04255.2 0.696 12-Jul R.RREELYR.Q "sp|Q9HCD5|NCOA5_HUMAN,tr|Q5JY17|Q5JY17_HUMAN" 2 1020.5465 1.77 126048 4255 2 1020.546857 511.2805 Nuclear receptor coactivator 5 OS=Homo sapiens OX=9606 GN=NCOA5 PE=1 SV=2 8.74 1400.2 - 590952 - - - 0.3723 - 1.451 0.021 - 120.2 1 2 1 0.0004 7 0 0 0 6.40E+06 3.62E+06 - - - 0.3755 0.9988 221125_WJC_METTL3_EV_vs_WT_F09.04261.04261.3 0.0223 Sep-40 R.HSPATISSSTR[166.11].G sp|O15119|TBX3_HUMAN 1 1152.5763 1.05 126052 4261 3 1152.575267 385.1994 T-box transcription factor TBX3 OS=Homo sapiens OX=9606 GN=TBX3 PE=1 SV=4 9.76 1401 - 344353 - - - -0.8702 - 1.595 0.296 - 101.5 1 2 0 -0.001 11 0 0 0 2.00E+07 1.91E+07 - - - 3.1661 0.9999 221125_WJC_METTL3_EV_vs_WT_F09.04262.04262.2 7.29E-07 18-Oct K.NNLPSNDSSK.F "sp|P17480|UBF1_HUMAN,tr|E9PMM2|E9PMM2_HUMAN,tr|E9PKP7|E9PKP7_HUMAN" 3 1074.4942 1.44 126053 4262 2 1074.493842 538.2544 Nucleolar transcription factor 1 OS=Homo sapiens OX=9606 GN=UBTF PE=1 SV=1 5.84 1401.2 - 423624 - - - -0.3015 - 1.989 0.591 - 382.2 1 2 0 -0.0003 10 0 0 0 2.54E+07 1.76E+07 - - - 5.3254 0.9999 221125_WJC_METTL3_EV_vs_WT_F09.04263.04263.2 5.88E-06 18-Nov K.NNLPSNDSSK[136.11].F "sp|P17480|UBF1_HUMAN,tr|E9PMM2|E9PMM2_HUMAN,tr|E9PKP7|E9PKP7_HUMAN" 3 1082.5084 1.44 126054 4263 2 1082.507129 542.2615 Nucleolar transcription factor 1 OS=Homo sapiens OX=9606 GN=UBTF PE=1 SV=1 5.84 1401.3 - 295338 - - - -1.1427 - 2.16 0.53 - 461.8 1 2 0 -0.0012 10 0 0 0 2.54E+07 1.76E+07 - - - 5.1048 0.9701 221125_WJC_METTL3_EV_vs_WT_F09.04265.04265.3 0.17 Jul-40 R.DVGDTC[160.03]SVGKK.D "sp|Q1ED39|KNOP1_HUMAN,tr|H3BPL4|H3BPL4_HUMAN" 2 1164.5445 1.21 126056 4265 3 1164.542935 389.1888 Lysine-rich nucleolar protein 1 OS=Homo sapiens OX=9606 GN=KNOP1 PE=1 SV=1 5.95 1401.6 - 163019 - - - -1.3336 - 1.367 0.176 - 49.9 2 2 0 -0.0016 11 0 0 0 1.42E+06 1.18E+06 - - - 1.2506 0.9237 221125_WJC_METTL3_EV_vs_WT_F09.04266.04266.2 0.0705 20-Jul R.NLEGANQHVSK[136.11].E "sp|Q86XP3|DDX42_HUMAN,tr|A0A0A0MSJ0|A0A0A0MSJ0_HUMAN" 2 1203.6087 1.66 126057 4266 2 1203.612906 602.8117 ATP-dependent RNA helicase DDX42 OS=Homo sapiens OX=9606 GN=DDX42 PE=1 SV=1 6.75 1401.7 - 70456.5 - - - 3.4538 - 1.291 0.098 - 141.1 1 2 0 0.0042 11 0 0 0 1.00E+06 6.05E+05 - - - 0.4545 1 221125_WJC_METTL3_EV_vs_WT_F09.04270.04270.2 2.11E-08 13/22 K.QSEAENTEQVNK.N "sp|Q9NRY5|F1142_HUMAN,tr|E7ESJ7|E7ESJ7_HUMAN" 2 1375.6216 1.58 126059 4270 2 1375.619819 688.8181 Protein FAM114A2 OS=Homo sapiens OX=9606 GN=FAM114A2 PE=1 SV=4 4.25 1402.2 - 740550 - - - -1.2598 - 2.755 0.624 - 664.3 1 2 0 -0.0017 12 0 0 0 6.90E+06 4.37E+06 - - - 6.3158 1 221125_WJC_METTL3_EV_vs_WT_F09.04272.04272.2 8.59E-09 14/22 K.QSEAENTEQVNK[136.11].N "sp|Q9NRY5|F1142_HUMAN,tr|E7ESJ7|E7ESJ7_HUMAN" 2 1383.6358 1.58 126061 4272 2 1383.636679 692.8252 Protein FAM114A2 OS=Homo sapiens OX=9606 GN=FAM114A2 PE=1 SV=4 4.25 1402.4 - 498240 - - - 0.67 - 2.558 0.592 - 865.3 1 2 0 0.0009 12 0 0 0 6.90E+06 4.37E+06 - - - 5.8845 0.9981 221125_WJC_METTL3_EV_vs_WT_F09.04275.04275.2 0.097 20-Jun R.NLEGANQHVSK.E "sp|Q86XP3|DDX42_HUMAN,tr|A0A0A0MSJ0|A0A0A0MSJ0_HUMAN" 2 1195.5945 1.58 126064 4275 2 1195.594597 598.8046 ATP-dependent RNA helicase DDX42 OS=Homo sapiens OX=9606 GN=DDX42 PE=1 SV=1 6.75 1402.8 - 125669 - - - 0.0401 - 1.175 0.319 - 87.8 1 2 0 0 11 0 0 0 1.00E+06 6.33E+05 - - - 1.8334 0.8847 221125_WJC_METTL3_EV_vs_WT_F09.04281.04281.3 0.148 Aug-36 K.GREEESDQIR.E sp|Q92620|PRP16_HUMAN 1 1217.5636 1.16 126069 4281 3 1217.564882 406.8618 Pre-mRNA-splicing factor ATP-dependent RNA helicase PRP16 OS=Homo sapiens OX=9606 GN=DHX38 PE=1 SV=2 4.41 1403.5 - 345840 - - - 1.0176 - 1.543 0.131 - 119 1 2 1 0.0012 10 0 0 0 3.02E+06 2.61E+06 - - - 1.2669 0.9998 221125_WJC_METTL3_EV_vs_WT_F09.04292.04292.3 0.000136 Aug-36 R.VR[166.11]IEGDNENK[136.11].L "sp|P51114|FXR1_HUMAN,tr|E7EU85|E7EU85_HUMAN,tr|E9PFF5|E9PFF5_HUMAN,tr|B4DXZ6|B4DXZ6_HUMAN" 4 1190.601 1.28 126078 4292 3 1190.601683 397.8743 Fragile X mental retardation syndrome-related protein 1 OS=Homo sapiens OX=9606 GN=FXR1 PE=1 SV=3 4.68 1404.9 - 750680 - - - 0.5443 - 1.771 0.512 - 66.9 1 2 1 0.0006 10 0 0 0 1.13E+07 8.81E+06 - - - 5.9173 0.9331 221125_WJC_METTL3_EV_vs_WT_F09.04293.04293.3 1.74 Aug-48 R.ASVAAQQQEEARR.S "sp|Q86UK7|ZN598_HUMAN,tr|H3BQQ2|H3BQQ2_HUMAN,tr|H3BPG6|H3BPG6_HUMAN" 3 1442.7226 0.6 126079 4293 3 1442.723953 481.9148 E3 ubiquitin-protein ligase ZNF598 OS=Homo sapiens OX=9606 GN=ZNF598 PE=1 SV=1 6.19 1405 - 273561 - - - 0.9357 - 1.301 0.132 - 59.6 1 2 0 0.0014 13 0 0 0 1.25E+06 2.08E+06 - - - 0.7247 0.9914 221125_WJC_METTL3_EV_vs_WT_F09.04296.04296.2 0.389 20-Apr R.GRPAVC[160.03]QPQGR.F sp|Q5T749|KPRP_HUMAN 1 1224.6146 999 126082 4296 2 1224.615444 613.3146 Keratinocyte proline-rich protein OS=Homo sapiens OX=9606 GN=KPRP PE=1 SV=1 10.35 1405.4 - 81991.7 - - - 0.7112 - 0.973 0.252 - 22.8 1 2 0 0.0009 11 0 0 0 7.16E+06 0.00E+00 - - - 0.828 1 221125_WJC_METTL3_EV_vs_WT_F09.04299.04299.3 4.60E-05 14/40 R.GRPAVC[160.03]QPQGR.F sp|Q5T749|KPRP_HUMAN 1 1224.6146 55.96 126083 4299 3 1224.615783 409.2121 Keratinocyte proline-rich protein OS=Homo sapiens OX=9606 GN=KPRP PE=1 SV=1 10.35 1405.8 - 2.14E+06 - - - 0.9881 - 2.446 0.467 - 351.1 1 2 0 0.0012 11 0 0 0 9.20E+07 1.64E+06 - - - 6.2872 0.9147 221125_WJC_METTL3_EV_vs_WT_F09.04302.04302.3 2.05 Oct-40 K.QLPAHDQDPSK[136.11].C "sp|Q9UGI8|TES_HUMAN,tr|F8W7T0|F8W7T0_HUMAN" 2 1242.6084 0.51 126086 4302 3 1242.608746 415.2101 Testin OS=Homo sapiens OX=9606 GN=TES PE=1 SV=1 5.21 1406.1 - 425139 - - - 0.2664 - 1.324 0.108 - 168.8 1 2 0 0.0003 11 0 0 0 2.71E+06 5.31E+06 - - - 0.5413 0.9907 221125_WJC_METTL3_EV_vs_WT_F09.04303.04303.3 0.0933 Sep-40 R.GGGSQHYPEER.H "sp|Q9NWH9|SLTM_HUMAN,tr|H7C3F4|H7C3F4_HUMAN,tr|H0YKH2|H0YKH2_HUMAN" 3 1215.5269 1.9 126087 4303 3 1215.530803 406.1829 SAFB-like transcription modulator OS=Homo sapiens OX=9606 GN=SLTM PE=1 SV=2 5.4 1406.3 - 310959 - - - 3.2406 - 1.769 0.238 - 108.5 1 2 0 0.0039 11 0 0 0 5.27E+06 2.78E+06 - - - 2.8128 0.7908 221125_WJC_METTL3_EV_vs_WT_F09.04304.04304.3 0.196 Sep-48 R.ASVAAQQQEEAR[166.11]R[166.11].S "sp|Q86UK7|ZN598_HUMAN,tr|H3BQQ2|H3BQQ2_HUMAN,tr|H3BPG6|H3BPG6_HUMAN" 3 1462.7391 0.6 126088 4304 3 1462.740967 488.587 E3 ubiquitin-protein ligase ZNF598 OS=Homo sapiens OX=9606 GN=ZNF598 PE=1 SV=1 6.19 1406.4 - 301259 - - - 1.247 - 1.484 0.044 - 121 1 2 0 0.0018 13 0 0 0 1.25E+06 2.08E+06 - - - 0.1003 0.9998 221125_WJC_METTL3_EV_vs_WT_F09.04305.04305.3 0.00114 Oct-36 R.THELEHSAIK.C "sp|Q93100|KPBB_HUMAN,tr|H3BV13|H3BV13_HUMAN,tr|I3NHZ9|I3NHZ9_HUMAN,tr|H3BQ89|H3BQ89_HUMAN" 4 1163.5935 1.27 126089 4305 3 1163.595426 388.8718 Phosphorylase b kinase regulatory subunit beta OS=Homo sapiens OX=9606 GN=PHKB PE=1 SV=3 5.94 1406.5 - 256731 - - - 1.6664 - 2.34 0.365 - 152.8 1 2 0 0.0019 10 0 0 0 4.44E+06 3.50E+06 - - - 5.0917 0.9988 221125_WJC_METTL3_EV_vs_WT_F09.04308.04308.2 0.0203 12-May R.HWDQNER[166.11].F "sp|P08195|4F2_HUMAN,tr|A0A7P0TAN7|A0A7P0TAN7_HUMAN,tr|J3KPF3|J3KPF3_HUMAN,tr|F5H056|F5H056_HUMAN,tr|F5GZI0|F5GZI0_HUMAN,tr|A0A7P0T9F7|A0A7P0T9F7_HUMAN,tr|A0A7P0TBF8|A0A7P0TBF8_HUMAN,tr|A0A7P0Z4A0|A0A7P0Z4A0_HUMAN,tr|F5GZS6|F5GZS6_HUMAN,tr|A0A7P0Z4P5|A0A7P0Z4P5_HUMAN" 10 993.4292 0.05 126092 4308 2 993.429623 497.7219 4F2 cell-surface antigen heavy chain OS=Homo sapiens OX=9606 GN=SLC3A2 PE=1 SV=3 5.32 1406.9 - 224175 - - - 0.4137 - 1.076 0.403 - 67 1 2 0 0.0004 7 0 0 0 3.51E+05 7.69E+06 - - - 2.2495 0.8115 221125_WJC_METTL3_EV_vs_WT_F09.04309.04309.2 0.148 16-Apr K.NTHC[160.03]SSLPH.Y "sp|P43243|MATR3_HUMAN,tr|B3KM87|B3KM87_HUMAN,tr|A8MXP9|A8MXP9_HUMAN,tr|A0A0R4J2E8|A0A0R4J2E8_HUMAN" 4 1051.4505 - 126093 4309 2 1051.453181 526.7325 Matrin-3 OS=Homo sapiens OX=9606 GN=MATR3 PE=1 SV=2 6.91 1407 - 194339 - - - 2.5232 - 0.985 0.438 - 63.4 1 1 0 0.0027 9 0 0 0 - - - - - 2.2315 0.9522 221125_WJC_METTL3_EV_vs_WT_F09.04310.04310.2 0.677 18-Jul R.VR[166.11]IEGDNENK[136.11].L "sp|P51114|FXR1_HUMAN,tr|E7EU85|E7EU85_HUMAN,tr|E9PFF5|E9PFF5_HUMAN,tr|B4DXZ6|B4DXZ6_HUMAN" 4 1190.601 1.71 126094 4310 2 1190.60269 596.3078 Fragile X mental retardation syndrome-related protein 1 OS=Homo sapiens OX=9606 GN=FXR1 PE=1 SV=3 4.68 1407.2 - 174686 - - - 1.3901 - 1.624 0.155 - 126.1 1 2 1 0.0017 10 0 0 0 2.15E+06 1.25E+06 - - - 1.5388 0.9842 221125_WJC_METTL3_EV_vs_WT_F09.04312.04312.2 0.00409 18-Jun R.TSDSTPDPQR.V "sp|P52948|NUP98_HUMAN,tr|H7C3P6|H7C3P6_HUMAN" 2 1102.4891 1.29 126096 4312 2 1102.495343 552.2518 Nuclear pore complex protein Nup98-Nup96 OS=Homo sapiens OX=9606 GN=NUP98 PE=1 SV=4 4.21 1407.4 - 71555.6 - - - 5.6799 - 1.323 0.432 - 115.8 1 2 0 0.0063 10 0 0 0 2.58E+07 2.00E+07 - - - 3.0111 0.9992 221125_WJC_METTL3_EV_vs_WT_F09.04320.04320.3 0.00271 Oct-40 K.NPSPTTRPVSR.R "sp|Q9ULV3|CIZ1_HUMAN,tr|Q5SYW2|Q5SYW2_HUMAN,tr|F5H2X7|F5H2X7_HUMAN,tr|H0Y5D5|H0Y5D5_HUMAN,tr|A0A0U1RQR2|A0A0U1RQR2_HUMAN,tr|A0A494C0L7|A0A494C0L7_HUMAN,tr|Q9BTG3|Q9BTG3_HUMAN" 7 1210.6418 2.51 126102 4320 3 1210.642985 404.5546 Cip1-interacting zinc finger protein OS=Homo sapiens OX=9606 GN=CIZ1 PE=1 SV=2 12 1408.5 - 5.85E+06 - - - 0.9507 - 1.876 0.29 - 171.3 1 2 0 0.0012 11 0 0 0 1.51E+08 6.05E+07 - - - 3.5602 0.9999 221125_WJC_METTL3_EV_vs_WT_F09.04325.04325.3 1.19E-05 Nov-44 K.HVLTGSADNSC[160.03]R.L "sp|Q13347|EIF3I_HUMAN,tr|A0A7I2YQT9|A0A7I2YQT9_HUMAN,tr|A0A7I2V613|A0A7I2V613_HUMAN,tr|A0A7I2V3N2|A0A7I2V3N2_HUMAN,tr|A0A7I2YQU2|A0A7I2YQU2_HUMAN,tr|A0A7I2YQX4|A0A7I2YQX4_HUMAN,tr|A0A7I2YQI6|A0A7I2YQI6_HUMAN,tr|A0A7I2YQF8|A0A7I2YQF8_HUMAN,tr|Q5TFK1|Q5TFK1_HUMAN,tr|A0A7I2V415|A0A7I2V415_HUMAN,tr|A0A7I2V3U3|A0A7I2V3U3_HUMAN,tr|A0A7I2V607|A0A7I2V607_HUMAN,tr|A0A7I2V640|A0A7I2V640_HUMAN,tr|A0A7P0MRT9|A0A7P0MRT9_HUMAN,tr|A0A7I2V3T4|A0A7I2V3T4_HUMAN,tr|A0A7I2V3K6|A0A7I2V3K6_HUMAN,tr|A0A7I2V4S8|A0A7I2V4S8_HUMAN,tr|A0A7I2V5V8|A0A7I2V5V8_HUMAN,tr|A0A7I2V391|A0A7I2V391_HUMAN,tr|A0A7I2V5E4|A0A7I2V5E4_HUMAN,tr|A0A7I2YQN1|A0A7I2YQN1_HUMAN,tr|A0A7I2V2M3|A0A7I2V2M3_HUMAN,tr|A0A7I2YQP9|A0A7I2YQP9_HUMAN,tr|A0A7I2YQI2|A0A7I2YQI2_HUMAN,tr|A0A7I2YQC8|A0A7I2YQC8_HUMAN,tr|A0A7I2V685|A0A7I2V685_HUMAN" 26 1315.5939 1.26 126107 4325 3 1315.59524 439.5386 Eukaryotic translation initiation factor 3 subunit I OS=Homo sapiens OX=9606 GN=EIF3I PE=1 SV=1 6.74 1409 - 555207 - - - 1.0201 - 1.918 0.444 - 227.4 1 2 0 0.0013 12 0 0 0 1.91E+07 1.52E+07 - - - 5.295 0.9922 221125_WJC_METTL3_EV_vs_WT_F09.04326.04326.2 7.11E-05 20-Dec A.STSQAQLSSQK.M "sp|Q8IWZ3|ANKH1_HUMAN,tr|A0A0A0MQZ8|A0A0A0MQZ8_HUMAN,tr|H0Y472|H0Y472_HUMAN,tr|H0Y7Y3|H0Y7Y3_HUMAN,tr|H0Y4P6|H0Y4P6_HUMAN,tr|H7C0V5|H7C0V5_HUMAN,tr|H0Y785|H0Y785_HUMAN" 7 1163.5782 1.29 126108 4326 2 1163.578645 582.7964 Ankyrin repeat and KH domain-containing protein 1 OS=Homo sapiens OX=9606 GN=ANKHD1 PE=1 SV=1 8.47 1409.1 - 523624 - - - 0.3567 - 2.204 0.491 - 729.4 1 1 0 0.0004 11 0 0 0 2.63E+06 2.03E+06 - - - 4.8053 0.9986 221125_WJC_METTL3_EV_vs_WT_F09.04327.04327.2 0.047 20-Sep K.NPSPTTRPVSR.R "sp|Q9ULV3|CIZ1_HUMAN,tr|Q5SYW2|Q5SYW2_HUMAN,tr|F5H2X7|F5H2X7_HUMAN,tr|H0Y5D5|H0Y5D5_HUMAN,tr|A0A0U1RQR2|A0A0U1RQR2_HUMAN,tr|A0A494C0L7|A0A494C0L7_HUMAN,tr|Q9BTG3|Q9BTG3_HUMAN" 7 1210.6418 2.93 126109 4327 2 1210.642524 606.3282 Cip1-interacting zinc finger protein OS=Homo sapiens OX=9606 GN=CIZ1 PE=1 SV=2 12 1409.3 - 398437 - - - 0.5699 - 1.689 0.235 - 83.6 1 2 0 0.0007 11 0 0 0 1.28E+07 4.35E+06 - - - 2.1944 0.9846 221125_WJC_METTL3_EV_vs_WT_F09.04329.04329.3 1.10E-05 17/52 T.ALAAQQQAAGKEEK.S sp|Q96A49|SYAP1_HUMAN 1 1441.7525 1.38 126111 4329 3 1441.753139 481.5914 Synapse-associated protein 1 OS=Homo sapiens OX=9606 GN=SYAP1 PE=1 SV=1 6.19 1409.5 - 393521 - - - 0.439 - 2.627 0.476 - 262.5 1 1 1 0.0006 14 0 0 0 1.07E+07 7.81E+06 - - - 6.4135 0.9999 221125_WJC_METTL3_EV_vs_WT_F09.04332.04332.2 0.000569 26-Oct R.ASPGGVSTSSSDGK.A sp|P54259|ATN1_HUMAN 1 1235.563 46.51 126114 4332 2 1235.562853 618.7888 Atrophin-1 OS=Homo sapiens OX=9606 GN=ATN1 PE=1 SV=3 5.88 1409.9 - 108732 - - - -0.0979 - 1.798 0.576 - 248.2 1 2 0 -0.0001 14 0 0 0 1.02E+06 2.19E+04 - - - 4.7675 0.9999 221125_WJC_METTL3_EV_vs_WT_F09.04339.04339.3 2.29E-05 Dec-36 R.QVHSTER[166.11]PFK[136.11].C "sp|P56270|MAZ_HUMAN,tr|H3BQI4|H3BQI4_HUMAN,tr|H3BQS2|H3BQS2_HUMAN,tr|I3L2Z5|I3L2Z5_HUMAN,tr|A0A087WWR2|A0A087WWR2_HUMAN" 5 1245.6585 3.68 126119 4339 3 1245.656589 416.2268 Myc-associated zinc finger protein OS=Homo sapiens OX=9606 GN=MAZ PE=1 SV=1 8.75 1410.8 - 3.32E+06 - - - -1.5261 - 2.217 0.428 - 163 1 2 0 -0.0019 10 0 0 0 7.68E+07 2.09E+07 - - - 5.6364 1 221125_WJC_METTL3_EV_vs_WT_F09.04341.04341.3 3.72E-06 Oct-44 K.HVLTGSADNSC[160.03]R[166.11].L "sp|Q13347|EIF3I_HUMAN,tr|A0A7I2YQT9|A0A7I2YQT9_HUMAN,tr|A0A7I2V613|A0A7I2V613_HUMAN,tr|A0A7I2V3N2|A0A7I2V3N2_HUMAN,tr|A0A7I2YQU2|A0A7I2YQU2_HUMAN,tr|A0A7I2YQX4|A0A7I2YQX4_HUMAN,tr|A0A7I2YQI6|A0A7I2YQI6_HUMAN,tr|A0A7I2YQF8|A0A7I2YQF8_HUMAN,tr|Q5TFK1|Q5TFK1_HUMAN,tr|A0A7I2V415|A0A7I2V415_HUMAN,tr|A0A7I2V3U3|A0A7I2V3U3_HUMAN,tr|A0A7I2V607|A0A7I2V607_HUMAN,tr|A0A7I2V640|A0A7I2V640_HUMAN,tr|A0A7P0MRT9|A0A7P0MRT9_HUMAN,tr|A0A7I2V3T4|A0A7I2V3T4_HUMAN,tr|A0A7I2V3K6|A0A7I2V3K6_HUMAN,tr|A0A7I2V4S8|A0A7I2V4S8_HUMAN,tr|A0A7I2V5V8|A0A7I2V5V8_HUMAN,tr|A0A7I2V391|A0A7I2V391_HUMAN,tr|A0A7I2V5E4|A0A7I2V5E4_HUMAN,tr|A0A7I2YQN1|A0A7I2YQN1_HUMAN,tr|A0A7I2V2M3|A0A7I2V2M3_HUMAN,tr|A0A7I2YQP9|A0A7I2YQP9_HUMAN,tr|A0A7I2YQI2|A0A7I2YQI2_HUMAN,tr|A0A7I2YQC8|A0A7I2YQC8_HUMAN,tr|A0A7I2V685|A0A7I2V685_HUMAN" 26 1325.6022 1.26 126121 4341 3 1325.602051 442.8747 Eukaryotic translation initiation factor 3 subunit I OS=Homo sapiens OX=9606 GN=EIF3I PE=1 SV=1 6.74 1410.9 - 3.59E+06 - - - -0.0883 - 1.892 0.531 - 195.9 1 2 0 -0.0001 12 0 0 0 1.91E+07 1.52E+07 - - - 6.2275 0.981 221125_WJC_METTL3_EV_vs_WT_F09.04342.04342.3 0.000112 16/52 T.ALAAQQQAAGK[136.11]EEK[136.11].S sp|Q96A49|SYAP1_HUMAN 1 1457.7809 1.38 126122 4342 3 1457.779875 486.9342 Synapse-associated protein 1 OS=Homo sapiens OX=9606 GN=SYAP1 PE=1 SV=1 6.19 1411 - 1.93E+06 - - - -0.7072 - 2.925 0.427 - 225.4 1 1 1 -0.001 14 0 0 0 1.07E+07 7.81E+06 - - - 6.1527 1 221125_WJC_METTL3_EV_vs_WT_F09.04343.04343.2 5.33E-09 22-Nov K.HVLTGSADNSC[160.03]R.L "sp|Q13347|EIF3I_HUMAN,tr|A0A7I2YQT9|A0A7I2YQT9_HUMAN,tr|A0A7I2V613|A0A7I2V613_HUMAN,tr|A0A7I2V3N2|A0A7I2V3N2_HUMAN,tr|A0A7I2YQU2|A0A7I2YQU2_HUMAN,tr|A0A7I2YQX4|A0A7I2YQX4_HUMAN,tr|A0A7I2YQI6|A0A7I2YQI6_HUMAN,tr|A0A7I2YQF8|A0A7I2YQF8_HUMAN,tr|Q5TFK1|Q5TFK1_HUMAN,tr|A0A7I2V415|A0A7I2V415_HUMAN,tr|A0A7I2V3U3|A0A7I2V3U3_HUMAN,tr|A0A7I2V607|A0A7I2V607_HUMAN,tr|A0A7I2V640|A0A7I2V640_HUMAN,tr|A0A7P0MRT9|A0A7P0MRT9_HUMAN,tr|A0A7I2V3T4|A0A7I2V3T4_HUMAN,tr|A0A7I2V3K6|A0A7I2V3K6_HUMAN,tr|A0A7I2V4S8|A0A7I2V4S8_HUMAN,tr|A0A7I2V5V8|A0A7I2V5V8_HUMAN,tr|A0A7I2V391|A0A7I2V391_HUMAN,tr|A0A7I2V5E4|A0A7I2V5E4_HUMAN,tr|A0A7I2YQN1|A0A7I2YQN1_HUMAN,tr|A0A7I2V2M3|A0A7I2V2M3_HUMAN,tr|A0A7I2YQP9|A0A7I2YQP9_HUMAN,tr|A0A7I2YQI2|A0A7I2YQI2_HUMAN,tr|A0A7I2YQC8|A0A7I2YQC8_HUMAN,tr|A0A7I2V685|A0A7I2V685_HUMAN" 26 1315.5939 1.21 126123 4343 2 1315.593088 658.8042 Eukaryotic translation initiation factor 3 subunit I OS=Homo sapiens OX=9606 GN=EIF3I PE=1 SV=1 6.74 1411.1 - 1.70E+06 - - - -0.6157 - 2.167 0.686 - 313 1 2 0 -0.0008 12 0 0 0 9.10E+06 7.54E+06 - - - 6.1423 0.9999 221125_WJC_METTL3_EV_vs_WT_F09.04344.04344.2 1.01E-07 22-Dec K.HVLTGSADNSC[160.03]R[166.11].L "sp|Q13347|EIF3I_HUMAN,tr|A0A7I2YQT9|A0A7I2YQT9_HUMAN,tr|A0A7I2V613|A0A7I2V613_HUMAN,tr|A0A7I2V3N2|A0A7I2V3N2_HUMAN,tr|A0A7I2YQU2|A0A7I2YQU2_HUMAN,tr|A0A7I2YQX4|A0A7I2YQX4_HUMAN,tr|A0A7I2YQI6|A0A7I2YQI6_HUMAN,tr|A0A7I2YQF8|A0A7I2YQF8_HUMAN,tr|Q5TFK1|Q5TFK1_HUMAN,tr|A0A7I2V415|A0A7I2V415_HUMAN,tr|A0A7I2V3U3|A0A7I2V3U3_HUMAN,tr|A0A7I2V607|A0A7I2V607_HUMAN,tr|A0A7I2V640|A0A7I2V640_HUMAN,tr|A0A7P0MRT9|A0A7P0MRT9_HUMAN,tr|A0A7I2V3T4|A0A7I2V3T4_HUMAN,tr|A0A7I2V3K6|A0A7I2V3K6_HUMAN,tr|A0A7I2V4S8|A0A7I2V4S8_HUMAN,tr|A0A7I2V5V8|A0A7I2V5V8_HUMAN,tr|A0A7I2V391|A0A7I2V391_HUMAN,tr|A0A7I2V5E4|A0A7I2V5E4_HUMAN,tr|A0A7I2YQN1|A0A7I2YQN1_HUMAN,tr|A0A7I2V2M3|A0A7I2V2M3_HUMAN,tr|A0A7I2YQP9|A0A7I2YQP9_HUMAN,tr|A0A7I2YQI2|A0A7I2YQI2_HUMAN,tr|A0A7I2YQC8|A0A7I2YQC8_HUMAN,tr|A0A7I2V685|A0A7I2V685_HUMAN" 26 1325.6022 1.21 126124 4344 2 1325.600652 663.8084 Eukaryotic translation initiation factor 3 subunit I OS=Homo sapiens OX=9606 GN=EIF3I PE=1 SV=1 6.74 1411.2 - 1.42E+06 - - - -1.1436 - 2.294 0.607 - 373.8 1 2 0 -0.0015 12 0 0 0 9.10E+06 7.54E+06 - - - 5.7085 0.9992 221125_WJC_METTL3_EV_vs_WT_F09.04355.04355.2 0.0236 18-Dec K.KTDAPQPDVK.E "sp|P27824|CALX_HUMAN,tr|A0A7P0T937|A0A7P0T937_HUMAN,tr|A0A7P0T840|A0A7P0T840_HUMAN,tr|A0A7P0TB65|A0A7P0TB65_HUMAN,tr|A0A7P0TAE9|A0A7P0TAE9_HUMAN,tr|D6RGY2|D6RGY2_HUMAN,tr|A0A7P0T8G1|A0A7P0T8G1_HUMAN,tr|A0A7P0Z484|A0A7P0Z484_HUMAN,tr|A0A7P0T9L0|A0A7P0T9L0_HUMAN" 9 1097.5717 2.33 126135 4355 2 1097.568554 549.7931 Calnexin OS=Homo sapiens OX=9606 GN=CANX PE=1 SV=2 5.96 1412.3 - 311980 - - - -2.8554 - 2.224 0.387 - 276.1 1 2 0 -0.0031 10 0 0 0 2.19E+06 9.39E+05 - - - 4.1295 1 221125_WJC_METTL3_EV_vs_WT_F09.04356.04356.2 4.86E-06 18-Dec R.LGNDFHTNKR.V "sp|P08708|RS17_HUMAN,tr|H0YN73|H0YN73_HUMAN,tr|H3BNC9|H3BNC9_HUMAN,tr|A0A0J9YYC4|A0A0J9YYC4_HUMAN,tr|H0YN88|H0YN88_HUMAN,tr|A0A075B716|A0A075B716_HUMAN" 6 1200.6 1.36 126136 4356 2 1200.600584 601.3073 40S ribosomal protein S17 OS=Homo sapiens OX=9606 GN=RPS17 PE=1 SV=2 8.75 1412.5 - 307733 - - - 0.5122 - 2.747 0.557 - 815.1 1 2 0 0.0006 10 0 0 0 7.50E+06 5.52E+06 - - - 5.9754 0.9452 221125_WJC_METTL3_EV_vs_WT_F09.04357.04357.2 0.0204 20-Aug A.STSQAQLSSQK[136.11].M "sp|Q8IWZ3|ANKH1_HUMAN,tr|A0A0A0MQZ8|A0A0A0MQZ8_HUMAN,tr|H0Y472|H0Y472_HUMAN,tr|H0Y7Y3|H0Y7Y3_HUMAN,tr|H0Y4P6|H0Y4P6_HUMAN,tr|H7C0V5|H7C0V5_HUMAN,tr|H0Y785|H0Y785_HUMAN" 7 1171.5924 1.29 126137 4357 2 1171.591976 586.8035 Ankyrin repeat and KH domain-containing protein 1 OS=Homo sapiens OX=9606 GN=ANKHD1 PE=1 SV=1 8.47 1412.6 - 296102 - - - -0.3875 - 1.588 0.287 - 148.5 1 1 0 -0.0005 11 0 0 0 2.63E+06 2.03E+06 - - - 2.4117 0.9948 221125_WJC_METTL3_EV_vs_WT_F09.04360.04360.2 6.07E-09 16-Nov L.GNDFHTNKR.V "sp|P08708|RS17_HUMAN,tr|H0YN73|H0YN73_HUMAN,tr|H3BNC9|H3BNC9_HUMAN,tr|A0A0J9YYC4|A0A0J9YYC4_HUMAN,tr|H0YN88|H0YN88_HUMAN,tr|A0A075B716|A0A075B716_HUMAN" 6 1087.5159 1.35 126139 4360 2 1087.515159 544.7652 40S ribosomal protein S17 OS=Homo sapiens OX=9606 GN=RPS17 PE=1 SV=2 8.75 1412.9 - 2.55E+06 - - - -0.686 - 2.15 0.603 - 609.5 1 1 0 -0.0007 9 0 0 0 1.03E+07 7.58E+06 - - - 5.7091 0.9998 221125_WJC_METTL3_EV_vs_WT_F09.04361.04361.2 4.72E-05 18-Nov R.LGNDFHTNK[136.11]R[166.11].V "sp|P08708|RS17_HUMAN,tr|H0YN73|H0YN73_HUMAN,tr|H3BNC9|H3BNC9_HUMAN,tr|A0A0J9YYC4|A0A0J9YYC4_HUMAN,tr|H0YN88|H0YN88_HUMAN,tr|A0A075B716|A0A075B716_HUMAN" 6 1218.6224 1.36 126140 4361 2 1218.620023 610.3185 40S ribosomal protein S17 OS=Homo sapiens OX=9606 GN=RPS17 PE=1 SV=2 8.75 1413.1 - 1.34E+06 - - - -1.9826 - 2.418 0.545 - 595.8 1 2 0 -0.0024 10 0 0 0 7.50E+06 5.52E+06 - - - 5.5302 1 221125_WJC_METTL3_EV_vs_WT_F09.04362.04362.3 0.00181 Dec-36 R.LGNDFHTNK[136.11]R[166.11].V "sp|P08708|RS17_HUMAN,tr|H0YN73|H0YN73_HUMAN,tr|H3BNC9|H3BNC9_HUMAN,tr|A0A0J9YYC4|A0A0J9YYC4_HUMAN,tr|H0YN88|H0YN88_HUMAN,tr|A0A075B716|A0A075B716_HUMAN" 6 1218.6224 1.27 126141 4362 3 1218.620123 407.2148 40S ribosomal protein S17 OS=Homo sapiens OX=9606 GN=RPS17 PE=1 SV=2 8.75 1413.1 - 3.05E+07 - - - -1.9005 - 2.725 0.484 - 239.6 1 2 0 -0.0023 10 0 0 0 1.46E+08 1.15E+08 - - - 6.8631 1 221125_WJC_METTL3_EV_vs_WT_F09.04363.04363.3 7.29E-07 Nov-36 K.KDDTDDEIAK.Y "sp|P27824|CALX_HUMAN,tr|A0A7P0T937|A0A7P0T937_HUMAN,tr|A0A7P0T840|A0A7P0T840_HUMAN,tr|A0A7P0Z4H2|A0A7P0Z4H2_HUMAN,tr|A0A7P0TB65|A0A7P0TB65_HUMAN,tr|A0A7P0TAN9|A0A7P0TAN9_HUMAN,tr|A0A7P0TAE9|A0A7P0TAE9_HUMAN,tr|A0A7P0T8N1|A0A7P0T8N1_HUMAN,tr|A0A7P0T8G1|A0A7P0T8G1_HUMAN,tr|A0A7P0Z4D6|A0A7P0Z4D6_HUMAN,tr|A0A7P0Z484|A0A7P0Z484_HUMAN,tr|A0A7P0TAR9|A0A7P0TAR9_HUMAN,tr|A0A7P0T9L0|A0A7P0T9L0_HUMAN,tr|D6RAQ8|D6RAQ8_HUMAN,tr|D6RAU8|D6RAU8_HUMAN" 15 1148.5197 0.98 126142 4363 3 1148.518021 383.8472 Calnexin OS=Homo sapiens OX=9606 GN=CANX PE=1 SV=2 4.04 1413.2 - 3.04E+06 - - - -1.4732 - 2.295 0.582 - 251.3 1 2 0 -0.0017 10 0 0 0 2.47E+07 2.52E+07 - - - 7.4544 1 221125_WJC_METTL3_EV_vs_WT_F09.04364.04364.2 0.000454 18-Nov K.KDDTDDEIAK.Y "sp|P27824|CALX_HUMAN,tr|A0A7P0T937|A0A7P0T937_HUMAN,tr|A0A7P0T840|A0A7P0T840_HUMAN,tr|A0A7P0Z4H2|A0A7P0Z4H2_HUMAN,tr|A0A7P0TB65|A0A7P0TB65_HUMAN,tr|A0A7P0TAN9|A0A7P0TAN9_HUMAN,tr|A0A7P0TAE9|A0A7P0TAE9_HUMAN,tr|A0A7P0T8N1|A0A7P0T8N1_HUMAN,tr|A0A7P0T8G1|A0A7P0T8G1_HUMAN,tr|A0A7P0Z4D6|A0A7P0Z4D6_HUMAN,tr|A0A7P0Z484|A0A7P0Z484_HUMAN,tr|A0A7P0TAR9|A0A7P0TAR9_HUMAN,tr|A0A7P0T9L0|A0A7P0T9L0_HUMAN,tr|D6RAQ8|D6RAQ8_HUMAN,tr|D6RAU8|D6RAU8_HUMAN" 15 1148.5197 1.56 126143 4364 2 1148.51794 575.2671 Calnexin OS=Homo sapiens OX=9606 GN=CANX PE=1 SV=2 4.04 1413.2 - 2.34E+06 - - - -1.5437 - 2.61 0.588 - 374.4 1 2 0 -0.0018 10 0 0 0 2.27E+07 1.46E+07 - - - 6.0612 0.9648 221125_WJC_METTL3_EV_vs_WT_F09.04367.04367.2 0.000393 14-Sep G.NDFHTNKR.V "sp|P08708|RS17_HUMAN,tr|H0YN73|H0YN73_HUMAN,tr|H3BNC9|H3BNC9_HUMAN,tr|A0A0J9YYC4|A0A0J9YYC4_HUMAN,tr|H0YN88|H0YN88_HUMAN,tr|A0A075B716|A0A075B716_HUMAN" 6 1030.4944 0.51 126146 4367 2 1030.492439 516.2545 40S ribosomal protein S17 OS=Homo sapiens OX=9606 GN=RPS17 PE=1 SV=2 8.75 1413.5 - 775746 - - - -1.9428 - 1.753 0.389 - 415.6 1 1 0 -0.002 8 0 0 0 3.68E+06 7.21E+06 - - - 3.6065 0.9989 221125_WJC_METTL3_EV_vs_WT_F09.04371.04371.2 0.0016 18-Sep R.TSDSTPDPQR[166.11].V "sp|P52948|NUP98_HUMAN,tr|H7C3P6|H7C3P6_HUMAN" 2 1112.4974 1.84 126150 4371 2 1112.493168 557.256 Nuclear pore complex protein Nup98-Nup96 OS=Homo sapiens OX=9606 GN=NUP98 PE=1 SV=4 4.21 1414 - 312932 - - - -3.76 - 1.965 0.504 - 272.7 1 2 0 -0.0042 10 0 0 0 2.41E+07 1.31E+07 - - - 4.6477 1 221125_WJC_METTL3_EV_vs_WT_F09.04378.04378.2 6.37E-08 14/18 K.K[136.11]DDTDDEIAK[136.11].Y "sp|P27824|CALX_HUMAN,tr|A0A7P0T937|A0A7P0T937_HUMAN,tr|A0A7P0T840|A0A7P0T840_HUMAN,tr|A0A7P0Z4H2|A0A7P0Z4H2_HUMAN,tr|A0A7P0TB65|A0A7P0TB65_HUMAN,tr|A0A7P0TAN9|A0A7P0TAN9_HUMAN,tr|A0A7P0TAE9|A0A7P0TAE9_HUMAN,tr|A0A7P0T8N1|A0A7P0T8N1_HUMAN,tr|A0A7P0T8G1|A0A7P0T8G1_HUMAN,tr|A0A7P0Z4D6|A0A7P0Z4D6_HUMAN,tr|A0A7P0Z484|A0A7P0Z484_HUMAN,tr|A0A7P0TAR9|A0A7P0TAR9_HUMAN,tr|A0A7P0T9L0|A0A7P0T9L0_HUMAN,tr|D6RAQ8|D6RAQ8_HUMAN,tr|D6RAU8|D6RAU8_HUMAN" 15 1164.5481 1.56 126156 4378 2 1164.544905 583.2813 Calnexin OS=Homo sapiens OX=9606 GN=CANX PE=1 SV=2 4.04 1414.9 - 2.30E+06 - - - -2.7547 - 2.974 0.654 - 602.9 1 2 0 -0.0032 10 0 0 0 2.27E+07 1.46E+07 - - - 6.9127 0.9997 221125_WJC_METTL3_EV_vs_WT_F09.04382.04382.3 0.00347 13/52 R.GVGSGGQGPPPPRR.E sp|P48634|PRC2A_HUMAN 1 1317.6902 0.4 126159 4382 3 1317.687953 440.2373 Protein PRRC2A OS=Homo sapiens OX=9606 GN=PRRC2A PE=1 SV=3 12 1415.2 - 2.00E+06 - - - -1.6908 - 1.835 0.388 - 163.3 1 2 0 -0.0022 14 0 0 0 3.13E+07 7.77E+07 - - - 4.4784 0.9996 221125_WJC_METTL3_EV_vs_WT_F09.04385.04385.2 0.00012 13/20 K.QQQQQQNDVVK.L "sp|Q15286|RAB35_HUMAN,tr|F5H157|F5H157_HUMAN" 2 1341.6637 1.3 126162 4385 2 1341.661486 671.8391 Ras-related protein Rab-35 OS=Homo sapiens OX=9606 GN=RAB35 PE=1 SV=1 5.84 1415.6 - 642368 - - - -1.6435 - 2.534 0.306 - 805.6 1 2 0 -0.0022 11 0 0 0 3.10E+07 2.38E+07 - - - 3.8157 0.9999 221125_WJC_METTL3_EV_vs_WT_F09.04386.04386.2 0.00333 13/20 K.QQQQQQNDVVK[136.11].L "sp|Q15286|RAB35_HUMAN,tr|F5H157|F5H157_HUMAN" 2 1349.6779 1.3 126163 4386 2 1349.676355 675.8462 Ras-related protein Rab-35 OS=Homo sapiens OX=9606 GN=RAB35 PE=1 SV=1 5.84 1415.7 - 615798 - - - -1.138 - 2.509 0.507 - 817.7 1 2 0 -0.0015 11 0 0 0 3.10E+07 2.38E+07 - - - 5.2737 0.9998 221125_WJC_METTL3_EV_vs_WT_F09.04391.04391.2 4.69E-05 18-Sep R.QQQSISENEK.L "sp|Q96KQ4|ASPP1_HUMAN,tr|A0A3B3ISJ2|A0A3B3ISJ2_HUMAN" 2 1189.5575 2.85 126168 4391 2 1189.556109 595.786 Apoptosis-stimulating of p53 protein 1 OS=Homo sapiens OX=9606 GN=PPP1R13B PE=1 SV=3 4.53 1416.3 - 382428 - - - -1.1651 - 2.037 0.487 - 418.9 1 2 0 -0.0014 10 0 0 0 3.15E+06 1.10E+06 - - - 4.6235 0.973 221125_WJC_METTL3_EV_vs_WT_F09.04393.04393.2 1.16 22-May K.NEPQNPGANSAR.G sp|P20339|RAB5A_HUMAN 1 1253.5749 -1 126170 4393 2 1253.57416 627.7947 Ras-related protein Rab-5A OS=Homo sapiens OX=9606 GN=RAB5A PE=1 SV=2 6 1416.6 - 188598 - - - -0.5712 - 0.973 0.138 - 78.8 1 2 0 -0.0007 12 0 0 0 0.00E+00 0.00E+00 - - - -0.012 0.9994 221125_WJC_METTL3_EV_vs_WT_F09.04398.04398.3 0.00816 Sep-40 K.MQVDQEEGHQK[136.11].C "sp|O95757|HS74L_HUMAN,tr|D6RJ96|D6RJ96_HUMAN,tr|E9PDE8|E9PDE8_HUMAN" 3 1335.5969 0.37 126173 4398 3 1335.595008 446.2062 Heat shock 70 kDa protein 4L OS=Homo sapiens OX=9606 GN=HSPA4L PE=1 SV=3 4.65 1417.1 - 2.00E+06 - - - -1.3896 - 1.784 0.332 - 113.7 1 2 0 -0.0019 11 0 0 0 2.47E+07 6.70E+07 - - - 3.8854 0.9996 221125_WJC_METTL3_EV_vs_WT_F09.04399.04399.3 0.000184 Nov-40 R.RPDQQLQGEGK.L sp|Q8NC51|PAIRB_HUMAN 1 1254.6317 0.76 126174 4399 3 1254.628149 419.2178 Plasminogen activator inhibitor 1 RNA-binding protein OS=Homo sapiens OX=9606 GN=SERBP1 PE=1 SV=2 6.07 1417.2 - 1.77E+06 - - - -2.8008 - 2.331 0.368 - 306.9 1 2 0 -0.0035 11 0 0 0 7.54E+08 9.91E+08 - - - 5.046 0.9735 221125_WJC_METTL3_EV_vs_WT_F09.04400.04400.3 0.0138 Sep-52 R.GVGSGGQGPPPPR[166.11]R[166.11].E sp|P48634|PRC2A_HUMAN 1 1337.7067 0.88 126175 4400 3 1337.708171 446.9095 Protein PRRC2A OS=Homo sapiens OX=9606 GN=PRRC2A PE=1 SV=3 12 1417.2 - 2.00E+06 - - - 1.0839 - 1.529 0.147 - 70.5 1 2 0 0.0014 14 0 0 0 2.67E+07 3.04E+07 - - - 1.3069 0.9998 221125_WJC_METTL3_EV_vs_WT_F09.04405.04405.2 0.0474 13/20 R.RPDQQLQGEGK.L sp|Q8NC51|PAIRB_HUMAN 1 1254.6317 0.75 126180 4405 2 1254.630317 628.3231 Plasminogen activator inhibitor 1 RNA-binding protein OS=Homo sapiens OX=9606 GN=SERBP1 PE=1 SV=2 6.07 1417.9 - 249917 - - - -1.0728 - 2.689 0.325 - 611.7 1 2 0 -0.0013 11 0 0 0 2.15E+08 2.88E+08 - - - 4.117 0.9991 221125_WJC_METTL3_EV_vs_WT_F09.04411.04411.2 0.000308 18-Jul K.GSSNSYAIK[136.11]K[136.11].K "sp|P46782|RS5_HUMAN,tr|M0QZN2|M0QZN2_HUMAN,tr|M0R0F0|M0R0F0_HUMAN,tr|M0R0R2|M0R0R2_HUMAN" 4 1069.5739 0.96 126183 4411 2 1069.570886 535.7942 40S ribosomal protein S5 OS=Homo sapiens OX=9606 GN=RPS5 PE=1 SV=4 9.7 1418.5 - 2.78E+06 - - - -2.7936 - 1.807 0.431 - 194 1 2 0 -0.003 10 0 0 0 1.88E+07 1.95E+07 - - - 3.875 0.9997 221125_WJC_METTL3_EV_vs_WT_F09.04412.04412.2 6.58E-07 18-Sep K.GSSNSYAIKK.K "sp|P46782|RS5_HUMAN,tr|M0QZN2|M0QZN2_HUMAN,tr|M0R0F0|M0R0F0_HUMAN,tr|M0R0R2|M0R0R2_HUMAN" 4 1053.5455 0.96 126184 4412 2 1053.54323 527.78 40S ribosomal protein S5 OS=Homo sapiens OX=9606 GN=RPS5 PE=1 SV=4 9.7 1418.6 - 2.78E+06 - - - -2.13 - 1.978 0.53 - 339.8 1 2 0 -0.0022 10 0 0 0 1.88E+07 1.95E+07 - - - 4.8588 0.9997 221125_WJC_METTL3_EV_vs_WT_F09.04415.04415.3 0.0192 Dec-44 K.VAETANEEEVKK.M "sp|P61221|ABCE1_HUMAN,tr|D6R9I9|D6R9I9_HUMAN" 2 1345.6725 1.28 126187 4415 3 1345.66929 449.5648 ATP-binding cassette sub-family E member 1 OS=Homo sapiens OX=9606 GN=ABCE1 PE=1 SV=1 4.49 1418.9 - 713928 - - - -2.404 - 2.179 0.392 - 159.5 1 2 0 -0.0032 12 0 0 0 3.85E+06 3.01E+06 - - - 5.0684 1 221125_WJC_METTL3_EV_vs_WT_F09.04417.04417.2 0.000154 20-Dec K.MQVDQEEGHQK[136.11].C "sp|O95757|HS74L_HUMAN,tr|D6RJ96|D6RJ96_HUMAN,tr|E9PDE8|E9PDE8_HUMAN" 3 1335.5969 0.02 126188 4417 2 1335.590489 668.8057 Heat shock 70 kDa protein 4L OS=Homo sapiens OX=9606 GN=HSPA4L PE=1 SV=3 4.65 1419.1 - 401613 - - - -4.7731 - 2.422 0.596 - 496.5 1 2 0 -0.0064 11 0 0 0 6.72E+04 3.18E+06 - - - 5.8341 0.9979 221125_WJC_METTL3_EV_vs_WT_F09.04446.04446.3 0.00303 Nov-36 K.YTQVGPDHNR.S sp|Q08211|DHX9_HUMAN 1 1185.5527 0.95 126205 4446 3 1185.545456 396.1915 ATP-dependent RNA helicase A OS=Homo sapiens OX=9606 GN=DHX9 PE=1 SV=4 6.74 1422.4 - 1.49E+06 - - - -6.0967 - 2.056 0.455 - 145.2 1 2 0 -0.0072 10 0 0 0 3.03E+07 3.20E+07 - - - 5.7157 0.9827 221125_WJC_METTL3_EV_vs_WT_F09.04447.04447.3 0.0507 Dec-40 K.TTGYSDRPTAR.R sp|Q9NP61|ARFG3_HUMAN 1 1223.5895 0.97 126206 4447 3 1223.581369 408.8704 ADP-ribosylation factor GTPase-activating protein 3 OS=Homo sapiens OX=9606 GN=ARFGAP3 PE=1 SV=1 8.41 1422.5 - 2.87E+06 - - - -6.6158 - 1.933 0.33 - 228.4 1 2 0 -0.0081 11 0 0 0 6.19E+07 6.36E+07 - - - 4.0892 0.9938 221125_WJC_METTL3_EV_vs_WT_F09.04454.04454.2 7.91E-05 18-Oct R.TPNGPNIDK[136.11]K[136.11].E "sp|Q92598|HS105_HUMAN,tr|Q5TBM3|Q5TBM3_HUMAN,tr|A0A0A0MSM0|A0A0A0MSM0_HUMAN" 3 1098.6004 0.09 126210 4454 2 1098.594155 550.3075 Heat shock protein 105 kDa OS=Homo sapiens OX=9606 GN=HSPH1 PE=1 SV=1 8.26 1423.5 - 828530 - - - -5.7054 - 1.814 0.461 - 342.7 1 2 0 -0.0063 10 0 0 0 1.57E+06 1.67E+07 - - - 4.1063 0.9841 221125_WJC_METTL3_EV_vs_WT_F09.04455.04455.2 2.11E-05 24-Dec R.SSSSGQHGSGLGE.S "sp|Q86YZ3|HORN_HUMAN,sp|Q86YZ3|HORN_HUMAN,sp|Q86YZ3|HORN_HUMAN" 3 1188.5007 - 126211 4455 2 1188.498055 595.2576 Hornerin OS=Homo sapiens OX=9606 GN=HRNR PE=1 SV=2 5.45 1423.6 - 620451 - - - -2.2322 - 2.273 0.536 - 380.9 1 1 0 -0.0027 13 0 0 0 - - - - - 5.1064 0.9983 221125_WJC_METTL3_EV_vs_WT_F09.04456.04456.3 7.87E-05 15/52 K.LQGTPSNK[136.11]EDAAAR[166.11].K "sp|O14686|KMT2D_HUMAN,tr|A0A804HHR9|A0A804HHR9_HUMAN" 2 1474.7495 1.91 126212 4456 3 1474.748283 492.5904 Histone-lysine N-methyltransferase 2D OS=Homo sapiens OX=9606 GN=KMT2D PE=1 SV=2 6.07 1423.7 - 517234 - - - -0.8184 - 2.765 0.251 - 341.8 1 2 1 -0.0012 14 0 0 0 1.51E+07 7.90E+06 - - - 4.0409 0.9991 221125_WJC_METTL3_EV_vs_WT_F09.04475.04475.3 0.00321 Oct-40 R.R[166.11]PDQQLQGEGK.L sp|Q8NC51|PAIRB_HUMAN 1 1264.6399 - 126227 4475 3 1264.637225 422.5539 Plasminogen activator inhibitor 1 RNA-binding protein OS=Homo sapiens OX=9606 GN=SERBP1 PE=1 SV=2 6.07 1425.8 - 1.31E+06 - - - -2.1413 - 1.918 0.318 - 215.3 1 2 0 -0.0027 11 0 0 0 - - - - - 3.9348 0.9998 221125_WJC_METTL3_EV_vs_WT_F09.04484.04484.2 1.90E-06 16/20 R.R[166.11]PDQQLQGEGK[136.11].L sp|Q8NC51|PAIRB_HUMAN 1 1272.6541 0.75 126235 4484 2 1272.651479 637.3343 Plasminogen activator inhibitor 1 RNA-binding protein OS=Homo sapiens OX=9606 GN=SERBP1 PE=1 SV=2 6.07 1426.9 - 1.77E+07 - - - -2.0854 - 2.759 0.485 - 820 1 2 0 -0.0027 11 0 0 0 2.15E+08 2.88E+08 - - - 5.3678 0.9997 221125_WJC_METTL3_EV_vs_WT_F09.04492.04492.3 0.000513 16/44 R.QIGASSR[166.11]PPPNR[166.11].T "sp|Q06787|FMR1_HUMAN,tr|R9WNI0|R9WNI0_HUMAN,tr|A8MQB8|A8MQB8_HUMAN,tr|G3V0J0|G3V0J0_HUMAN" 4 1298.6958 -1 126241 4492 3 1298.693168 433.9059 Synaptic functional regulator FMR1 OS=Homo sapiens OX=9606 GN=FMR1 PE=1 SV=1 12 1427.7 - 520955 - - - -2.0436 - 2.165 0.361 - 408.8 1 2 0 -0.0027 12 0 0 0 0.00E+00 0.00E+00 - - - 4.7051 0.8508 221125_WJC_METTL3_EV_vs_WT_F09.04497.04497.2 1.69 18-May K.EK[136.11]PVC[160.03]GTTYK[136.11].V "sp|Q14444|CAPR1_HUMAN,tr|G3V153|G3V153_HUMAN" 2 1197.6035 0.64 126246 4497 2 1197.602237 599.809 Caprin-1 OS=Homo sapiens OX=9606 GN=CAPRIN1 PE=1 SV=2 8.27 1428.4 - 206526 - - - -1.0212 - 0.996 0.006 - 51.6 2 2 0 -0.0012 10 0 0 0 9.02E+05 1.40E+06 - - - -1.0607 0.9998 221125_WJC_METTL3_EV_vs_WT_F09.04500.04500.3 0.00377 Nov-40 K.GVPIC[160.03]HQTQQK.Q sp|P23490|LORI_HUMAN 1 1294.6452 18.49 126247 4500 3 1294.642193 432.5557 Loricrin OS=Homo sapiens OX=9606 GN=LORICRIN PE=1 SV=2 8.23 1428.8 - 1.18E+06 - - - -2.3265 - 2.337 0.389 - 122.2 1 2 0 -0.003 11 0 0 0 7.69E+06 4.16E+05 - - - 5.2876 0.906 221125_WJC_METTL3_EV_vs_WT_F09.04513.04513.2 0.483 20-Apr K.GVPIC[160.03]HQTQQK.Q sp|P23490|LORI_HUMAN 1 1294.6452 999 126259 4513 2 1294.646027 648.3299 Loricrin OS=Homo sapiens OX=9606 GN=LORICRIN PE=1 SV=2 8.23 1430.3 - 123222 - - - 0.6349 - 0.907 0.079 - 43.4 2 2 0 0.0008 11 0 0 0 6.83E+05 0.00E+00 - - - -0.7743 0.9971 221125_WJC_METTL3_EV_vs_WT_F09.04514.04514.2 0.0171 16-Aug R.TGHWLNHGK[136.11].E sp|Q86U44|MTA70_HUMAN 1 1056.5345 -1 126260 4514 2 1056.534848 529.2745 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 8.47 1430.4 - 111841 - - - 0.3653 - 1.23 0.259 - 179.3 1 2 0 0.0004 9 0 0 0 0.00E+00 0.00E+00 - - - 1.5528 0.9993 221125_WJC_METTL3_EV_vs_WT_F09.04520.04520.3 0.0225 Nov-44 R.QIGASSRPPPNR.T "sp|Q06787|FMR1_HUMAN,tr|R9WNI0|R9WNI0_HUMAN,tr|A8MQB8|A8MQB8_HUMAN,tr|G3V0J0|G3V0J0_HUMAN" 4 1278.6793 2.7 126263 4520 3 1278.680162 427.2337 Synaptic functional regulator FMR1 OS=Homo sapiens OX=9606 GN=FMR1 PE=1 SV=1 12 1431.2 - 2.39E+06 - - - 0.6882 - 1.784 0.309 - 160.1 1 2 0 0.0009 12 0 0 0 4.57E+07 1.69E+07 - - - 3.5893 0.9991 221125_WJC_METTL3_EV_vs_WT_F09.04527.04527.2 3.30E-05 18-Oct K.NSVNSHTIGR.Y "sp|Q08188|TGM3_HUMAN,tr|A0A494C0J7|A0A494C0J7_HUMAN" 2 1083.5421 9.55 126270 4527 2 1083.538569 542.7783 Protein-glutamine gamma-glutamyltransferase E OS=Homo sapiens OX=9606 GN=TGM3 PE=1 SV=4 9.76 1431.9 - 220349 - - - -3.2772 - 2.09 0.439 - 537.7 1 2 0 -0.0036 10 0 0 0 1.27E+06 1.33E+05 - - - 4.34 0.9997 221125_WJC_METTL3_EV_vs_WT_F09.04531.04531.2 9.18E-07 22-Oct K.EGNTEQPVQTSK.L "sp|Q9P2K3|RCOR3_HUMAN,tr|B4DV59|B4DV59_HUMAN,tr|H0YDD7|H0YDD7_HUMAN" 3 1316.6208 1.47 126274 4531 2 1316.623471 659.3177 REST corepressor 3 OS=Homo sapiens OX=9606 GN=RCOR3 PE=1 SV=2 4.53 1432.5 - 88236 - - - 2.0104 - 1.954 0.554 - 291.8 1 2 0 0.0026 12 0 0 0 2.24E+06 1.53E+06 - - - 4.8946 0.9997 221125_WJC_METTL3_EV_vs_WT_F09.04533.04533.3 0.000286 Oct-40 R.R[166.11]PDQQLQGEGK[136.11].L sp|Q8NC51|PAIRB_HUMAN 1 1272.6541 0.76 126275 4533 3 1272.653927 425.2253 Plasminogen activator inhibitor 1 RNA-binding protein OS=Homo sapiens OX=9606 GN=SERBP1 PE=1 SV=2 6.07 1432.7 - 726551 - - - -0.1619 - 1.975 0.332 - 133.7 1 2 0 -0.0002 11 0 0 0 7.54E+08 9.91E+08 - - - 4.1748 0.9997 221125_WJC_METTL3_EV_vs_WT_F09.04545.04545.2 0.00471 13/14 K.R[166.11]FTDEESR[166.11].V "sp|Q9NYF8|BCLF1_HUMAN,tr|H0YF00|H0YF00_HUMAN,tr|E9PKI6|E9PKI6_HUMAN,tr|A0A1W2PQ43|A0A1W2PQ43_HUMAN,tr|E9PK91|E9PK91_HUMAN,tr|E9PK09|E9PK09_HUMAN,tr|E9PQN2|E9PQN2_HUMAN" 7 1058.4896 2.4 126286 4545 2 1058.489236 530.2521 Bcl-2-associated transcription factor 1 OS=Homo sapiens OX=9606 GN=BCLAF1 PE=1 SV=2 4.68 1433.9 - 401412 - - - -0.3222 - 2.445 0.232 - 733.7 1 2 0 -0.0003 8 0 0 0 6.31E+06 2.63E+06 - - - 3.4508 0.9958 221125_WJC_METTL3_EV_vs_WT_F09.04546.04546.3 0.0911 Nov-44 R.TPPK[136.11]EEQSENLK[136.11].H sp|Q5SWX8|ODR4_HUMAN 1 1414.7275 1.96 126287 4546 3 1414.727062 472.5831 Protein odr-4 homolog OS=Homo sapiens OX=9606 GN=ODR4 PE=1 SV=1 4.78 1434.1 - 764728 - - - -0.2912 - 1.872 0.278 - 123.3 1 2 1 -0.0004 12 0 0 0 4.48E+07 2.28E+07 - - - 3.3773 0.9997 221125_WJC_METTL3_EV_vs_WT_F09.04548.04548.2 4.02E-05 13/18 K.HSEVQQANLK[136.11].A "sp|P35606|COPB2_HUMAN,tr|H0Y938|H0Y938_HUMAN,tr|A0A7I2V258|A0A7I2V258_HUMAN,tr|H0YAC7|H0YAC7_HUMAN" 4 1160.6029 0.52 126289 4548 2 1160.600331 581.3087 Coatomer subunit beta' OS=Homo sapiens OX=9606 GN=COPB2 PE=1 SV=2 6.75 1434.3 - 311729 - - - -2.2445 - 2.723 0.44 - 415.8 1 2 0 -0.0026 10 0 0 0 1.89E+07 3.66E+07 - - - 5.0862 1 221125_WJC_METTL3_EV_vs_WT_F09.04549.04549.2 2.36E-08 13/16 R.HSDGNLC[160.03]VK.V "sp|P49458|SRP09_HUMAN,tr|Q659G3|Q659G3_HUMAN,tr|E9PE20|E9PE20_HUMAN,tr|Q6P2S0|Q6P2S0_HUMAN" 4 1028.4709 1.81 126290 4549 2 1028.469588 515.2427 Signal recognition particle 9 kDa protein OS=Homo sapiens OX=9606 GN=SRP9 PE=1 SV=2 6.73 1434.4 - 306779 - - - -1.3039 - 2.611 0.694 - 443.3 1 2 0 -0.0013 9 0 0 0 8.74E+06 4.84E+06 - - - 6.943 0.9998 221125_WJC_METTL3_EV_vs_WT_F09.04550.04550.2 0.000434 18-Sep K.KDVDSAYMNK.V sp|P12035|K2C3_HUMAN 1 1169.5387 56.69 126291 4550 2 1169.537964 585.7766 "Keratin, type II cytoskeletal 3 OS=Homo sapiens OX=9606 GN=KRT3 PE=1 SV=3" 5.96 1434.6 - 270544 - - - -0.6071 - 2.021 0.454 - 237.8 1 2 0 -0.0007 10 0 0 0 1.80E+07 3.18E+05 - - - 4.358 0.9999 221125_WJC_METTL3_EV_vs_WT_F09.04553.04553.2 1.70E-06 22-Oct K.EGNTEQPVQTSK[136.11].L "sp|Q9P2K3|RCOR3_HUMAN,tr|B4DV59|B4DV59_HUMAN,tr|H0YDD7|H0YDD7_HUMAN" 3 1324.635 1.47 126294 4553 2 1324.634853 663.3248 REST corepressor 3 OS=Homo sapiens OX=9606 GN=RCOR3 PE=1 SV=2 4.53 1434.9 - 147541 - - - -0.1291 - 2.053 0.544 - 299.2 1 2 0 -0.0002 12 0 0 0 2.24E+06 1.53E+06 - - - 4.9515 0.9842 221125_WJC_METTL3_EV_vs_WT_F09.04557.04557.2 0.854 18-Jun R.QR[166.11]PDLGSAQK[136.11].G "sp|P33991|MCM4_HUMAN,tr|A0A3B3IT92|A0A3B3IT92_HUMAN,tr|A0A3B3IU45|A0A3B3IU45_HUMAN,tr|A0A3B3ITP6|A0A3B3ITP6_HUMAN,tr|E5RFR3|E5RFR3_HUMAN,tr|A0A3B3IS57|A0A3B3IS57_HUMAN" 6 1116.6006 0.33 126297 4557 2 1116.601082 559.3076 DNA replication licensing factor MCM4 OS=Homo sapiens OX=9606 GN=MCM4 PE=1 SV=5 8.75 1435.5 - 134340 - - - 0.3949 - 1.105 0.14 - 98 1 2 0 0.0004 10 0 0 0 3.63E+05 1.10E+06 - - - 0.3536 0.9993 221125_WJC_METTL3_EV_vs_WT_F09.04560.04560.3 0.000168 13/40 R.YLEEQKTENGK.D "sp|Q9Y2W1|TR150_HUMAN,tr|A0A3B3ITZ9|A0A3B3ITZ9_HUMAN" 2 1337.6463 3.41 126300 4560 3 1337.645557 446.8894 Thyroid hormone receptor-associated protein 3 OS=Homo sapiens OX=9606 GN=THRAP3 PE=1 SV=2 4.79 1435.6 - 5.29E+06 - - - -0.5629 - 2.016 0.385 - 135.2 1 2 1 -0.0008 11 0 0 0 3.83E+07 1.12E+07 - - - 4.8239 0.9972 221125_WJC_METTL3_EV_vs_WT_F09.04561.04561.3 0.202 Nov-40 R.YLEEQK[136.11]TENGK[136.11].D "sp|Q9Y2W1|TR150_HUMAN,tr|A0A3B3ITZ9|A0A3B3ITZ9_HUMAN" 2 1353.6747 3.38 126301 4561 3 1353.673092 452.2322 Thyroid hormone receptor-associated protein 3 OS=Homo sapiens OX=9606 GN=THRAP3 PE=1 SV=2 4.79 1435.7 - 2.27E+06 - - - -1.1953 - 1.604 0.345 - 106 1 2 1 -0.0016 11 0 0 0 3.80E+07 1.12E+07 - - - 3.7283 0.9995 221125_WJC_METTL3_EV_vs_WT_F09.04562.04562.3 0.00155 13/40 R.LRENAAHLGDK.R "sp|Q9HCM9|TRI39_HUMAN,tr|A0A0G2JKY0|A0A0G2JKY0_HUMAN,tr|A0A096LP39|A0A096LP39_HUMAN,tr|A0A140TA46|A0A140TA46_HUMAN,tr|A2AAZ6|A2AAZ6_HUMAN,tr|H0Y735|H0Y735_HUMAN" 6 1222.6418 2.26 126302 4562 3 1222.639707 408.5546 E3 ubiquitin-protein ligase TRIM39 OS=Homo sapiens OX=9606 GN=TRIM39 PE=1 SV=2 6.75 1435.7 - 1.76E+06 - - - -1.7397 - 2.614 0.373 - 251.5 1 2 1 -0.0021 11 0 0 0 1.59E+07 7.03E+06 - - - 5.4277 0.9998 221125_WJC_METTL3_EV_vs_WT_F09.04563.04563.3 0.000592 Nov-36 R.KAYLEPEHTK.A "sp|Q70IA6|MOB2_HUMAN,tr|A0A087WVS8|A0A087WVS8_HUMAN" 2 1214.6295 1.37 126303 4563 3 1214.627435 405.8838 MOB kinase activator 2 OS=Homo sapiens OX=9606 GN=MOB2 PE=1 SV=1 6.76 1435.8 - 1.62E+06 - - - -1.7314 - 2.238 0.365 - 214.9 1 2 0 -0.0021 10 0 0 0 1.23E+07 8.96E+06 - - - 4.9615 1 221125_WJC_METTL3_EV_vs_WT_F09.04564.04564.2 2.89E-06 13/18 K.ESDLSHVQNK.S "sp|O43390|HNRPR_HUMAN,tr|A0A6Q8PH31|A0A6Q8PH31_HUMAN,tr|A0A6Q8PH35|A0A6Q8PH35_HUMAN" 3 1155.552 1.51 126304 4564 2 1155.549903 578.7833 Heterogeneous nuclear ribonucleoprotein R OS=Homo sapiens OX=9606 GN=HNRNPR PE=1 SV=1 5.32 1435.9 - 1.52E+06 - - - -1.8286 - 2.752 0.582 - 645 1 2 0 -0.0021 10 0 0 0 2.45E+07 1.62E+07 - - - 6.1647 0.9977 221125_WJC_METTL3_EV_vs_WT_F09.04570.04570.2 0.000594 20-Aug R.YLEEQKTENGK.D "sp|Q9Y2W1|TR150_HUMAN,tr|A0A3B3ITZ9|A0A3B3ITZ9_HUMAN" 2 1337.6463 3.32 126309 4570 2 1337.6457 669.8304 Thyroid hormone receptor-associated protein 3 OS=Homo sapiens OX=9606 GN=THRAP3 PE=1 SV=2 4.79 1436.6 - 367366 - - - -0.456 - 1.691 0.49 - 160.4 1 2 1 -0.0006 11 0 0 0 2.69E+06 8.11E+05 - - - 4.0811 0.9968 221125_WJC_METTL3_EV_vs_WT_F09.04573.04573.2 0.00906 18-Sep R.INVVNNHQAK[136.11].Q "sp|Q9BY77|PDIP3_HUMAN,tr|F6VRR5|F6VRR5_HUMAN,tr|F8WCX5|F8WCX5_HUMAN" 3 1143.624 1.99 126312 4573 2 1143.620108 572.8193 Polymerase delta-interacting protein 3 OS=Homo sapiens OX=9606 GN=POLDIP3 PE=1 SV=2 8.76 1437 - 107244 - - - -3.4076 - 1.815 0.305 - 263.1 1 2 0 -0.0039 10 0 0 0 2.39E+06 1.20E+06 - - - 2.9564 0.9303 221125_WJC_METTL3_EV_vs_WT_F09.04579.04579.2 0.00356 16-Sep R.ESDGFREEK.N "sp|Q9NYF8|BCLF1_HUMAN,tr|E9PKI6|E9PKI6_HUMAN,tr|A0A1W2PQ43|A0A1W2PQ43_HUMAN,tr|E9PK91|E9PK91_HUMAN,tr|E9PK09|E9PK09_HUMAN,tr|E9PQN2|E9PQN2_HUMAN" 6 1095.4833 2.5 126315 4579 2 1095.480673 548.7489 Bcl-2-associated transcription factor 1 OS=Homo sapiens OX=9606 GN=BCLAF1 PE=1 SV=2 4.41 1437.7 - 1.97E+06 - - - -2.3679 - 1.829 0.118 - 359.2 1 2 1 -0.0026 9 0 0 0 7.09E+07 2.84E+07 - - - 1.6585 0.9995 221125_WJC_METTL3_EV_vs_WT_F09.04580.04580.3 0.00535 Nov-40 K.DVKPKPIADAK.A "sp|P27816|MAP4_HUMAN,tr|E7EVA0|E7EVA0_HUMAN,tr|H7C4C5|H7C4C5_HUMAN,tr|A0A804HKE7|A0A804HKE7_HUMAN,tr|B5MEG9|B5MEG9_HUMAN" 5 1180.6816 0.53 126316 4580 3 1180.679081 394.5678 Microtubule-associated protein 4 OS=Homo sapiens OX=9606 GN=MAP4 PE=1 SV=3 8.5 1437.8 - 1.42E+06 - - - -2.1106 - 2.375 0.308 - 105.4 1 2 0 -0.0025 11 0 0 0 9.65E+06 1.82E+07 - - - 4.4305 0.9948 221125_WJC_METTL3_EV_vs_WT_F09.04581.04581.3 2.34E-05 14/40 R.LR[166.11]ENAAHLGDK[136.11].R "sp|Q9HCM9|TRI39_HUMAN,tr|A0A0G2JKY0|A0A0G2JKY0_HUMAN,tr|A0A096LP39|A0A096LP39_HUMAN,tr|A0A140TA46|A0A140TA46_HUMAN,tr|A2AAZ6|A2AAZ6_HUMAN,tr|H0Y735|H0Y735_HUMAN" 6 1240.6643 2.26 126317 4581 3 1240.655667 414.562 E3 ubiquitin-protein ligase TRIM39 OS=Homo sapiens OX=9606 GN=TRIM39 PE=1 SV=2 6.75 1437.8 - 1.36E+06 - - - -6.9616 - 2.795 0.513 - 257.2 1 2 1 -0.0086 11 0 0 0 1.59E+07 7.03E+06 - - - 7.1769 1 221125_WJC_METTL3_EV_vs_WT_F09.04582.04582.3 1.49E-05 17/52 K.IDSEGGVSANHTSR.A "sp|P51659|DHB4_HUMAN,tr|A0A2R8Y7L2|A0A2R8Y7L2_HUMAN,tr|A0A2R8YD50|A0A2R8YD50_HUMAN,tr|A0A804HIR1|A0A804HIR1_HUMAN,tr|E7ET17|E7ET17_HUMAN,tr|E7ER27|E7ER27_HUMAN,tr|E7EPL9|E7EPL9_HUMAN,tr|A0A804HKU2|A0A804HKU2_HUMAN,tr|A0A804HK65|A0A804HK65_HUMAN" 9 1428.6593 0.62 126318 4582 3 1428.657478 477.2271 Peroxisomal multifunctional enzyme type 2 OS=Homo sapiens OX=9606 GN=HSD17B4 PE=1 SV=3 5.32 1437.9 - 1.01E+06 - - - -1.2991 - 2.935 0.527 - 317.5 1 2 0 -0.0019 14 0 0 0 6.30E+06 1.02E+07 - - - 7.2764 0.9998 221125_WJC_METTL3_EV_vs_WT_F09.04583.04583.3 0.00105 Oct-48 K.TATPQQAQEVHEK.L "sp|P60174|TPIS_HUMAN,tr|U3KPZ0|U3KPZ0_HUMAN" 2 1465.7161 1.43 126319 4583 3 1465.717833 489.5793 Triosephosphate isomerase OS=Homo sapiens OX=9606 GN=TPI1 PE=1 SV=4 5.37 1438 - 925051 - - - 1.168 - 2.214 0.379 - 109.9 1 2 0 0.0017 13 0 0 0 5.25E+07 3.67E+07 - - - 4.9199 0.9998 221125_WJC_METTL3_EV_vs_WT_F09.04584.04584.3 2.42E-05 14/36 R.VRYDSSNQVK.G "sp|O95983|MBD3_HUMAN,tr|A0A087X1H1|A0A087X1H1_HUMAN,tr|K7EIE8|K7EIE8_HUMAN,tr|A0A087WT34|A0A087WT34_HUMAN,tr|A0A0A0MTS6|A0A0A0MTS6_HUMAN,tr|A0A087WZ12|A0A087WZ12_HUMAN" 6 1194.5993 1.16 126320 4584 3 1194.597906 399.207 Methyl-CpG-binding domain protein 3 OS=Homo sapiens OX=9606 GN=MBD3 PE=1 SV=1 8.56 1438.1 - 913191 - - - -1.1669 - 2.352 0.474 - 412 1 2 1 -0.0014 10 0 0 0 2.66E+07 2.31E+07 - - - 6.322 0.971 221125_WJC_METTL3_EV_vs_WT_F09.04589.04589.2 0.15 18-Jul R.VRYDSSNQVK.G "sp|O95983|MBD3_HUMAN,tr|A0A087X1H1|A0A087X1H1_HUMAN,tr|K7EIE8|K7EIE8_HUMAN,tr|A0A087WT34|A0A087WT34_HUMAN,tr|A0A0A0MTS6|A0A0A0MTS6_HUMAN,tr|A0A087WZ12|A0A087WZ12_HUMAN" 6 1194.5993 1.46 126325 4589 2 1194.59674 598.3069 Methyl-CpG-binding domain protein 3 OS=Homo sapiens OX=9606 GN=MBD3 PE=1 SV=1 8.56 1438.7 - 148587 - - - -2.143 - 1.456 0.296 - 172.5 1 2 1 -0.0026 10 0 0 0 3.99E+06 2.74E+06 - - - 2.2751 0.9999 221125_WJC_METTL3_EV_vs_WT_F09.04594.04594.3 0.000945 Nov-40 K.DVK[136.11]PK[136.11]PIADAK[136.11].A "sp|P27816|MAP4_HUMAN,tr|E7EVA0|E7EVA0_HUMAN,tr|H7C4C5|H7C4C5_HUMAN,tr|A0A804HKE7|A0A804HKE7_HUMAN,tr|B5MEG9|B5MEG9_HUMAN" 5 1204.7242 0.53 126328 4594 3 1204.722607 402.582 Microtubule-associated protein 4 OS=Homo sapiens OX=9606 GN=MAP4 PE=1 SV=3 8.5 1439.2 - 2.61E+06 - - - -1.2999 - 2.293 0.424 - 104.7 1 2 0 -0.0016 11 0 0 0 9.65E+06 1.82E+07 - - - 5.6242 0.9998 221125_WJC_METTL3_EV_vs_WT_F09.04596.04596.3 2.19E-05 13/32 R.ER[166.11]ELEEC[160.03]QR[166.11].N "sp|Q9UNE7|CHIP_HUMAN,tr|H3BUD0|H3BUD0_HUMAN,tr|H3BS86|H3BS86_HUMAN,tr|H3BTA3|H3BTA3_HUMAN" 4 1267.573 0.32 126330 4596 3 1267.572652 423.5316 E3 ubiquitin-protein ligase CHIP OS=Homo sapiens OX=9606 GN=STUB1 PE=1 SV=2 4.49 1439.4 - 1.36E+06 - - - -0.2659 - 2.567 0.45 - 452.3 1 2 1 -0.0003 9 0 0 0 6.16E+06 1.92E+07 - - - 6.3982 1 221125_WJC_METTL3_EV_vs_WT_F09.04597.04597.3 3.72E-06 16/48 K.TATPQQAQEVHEK[136.11].L "sp|P60174|TPIS_HUMAN,tr|U3KPZ0|U3KPZ0_HUMAN" 2 1473.7303 1.43 126331 4597 3 1473.729346 492.2507 Triosephosphate isomerase OS=Homo sapiens OX=9606 GN=TPI1 PE=1 SV=4 5.37 1439.4 - 1.31E+06 - - - -0.6616 - 2.357 0.484 - 335.8 1 2 0 -0.001 13 0 0 0 5.25E+07 3.67E+07 - - - 6.2605 0.9965 221125_WJC_METTL3_EV_vs_WT_F09.04599.04599.2 0.0072 16-Sep R.ER[166.11]ELEEC[160.03]QR[166.11].N "sp|Q9UNE7|CHIP_HUMAN,tr|H3BUD0|H3BUD0_HUMAN,tr|H3BS86|H3BS86_HUMAN,tr|H3BTA3|H3BTA3_HUMAN" 4 1267.573 0.25 126332 4599 2 1267.571687 634.7938 E3 ubiquitin-protein ligase CHIP OS=Homo sapiens OX=9606 GN=STUB1 PE=1 SV=2 4.49 1439.7 - 220972 - - - -1.0272 - 1.728 0.424 - 175.9 1 2 1 -0.0013 9 0 0 0 6.70E+05 2.63E+06 - - - 3.7547 0.9668 221125_WJC_METTL3_EV_vs_WT_F09.04602.04602.3 0.0689 Aug-36 R.VR[166.11]YDSSNQVK[136.11].G "sp|O95983|MBD3_HUMAN,tr|A0A087X1H1|A0A087X1H1_HUMAN,tr|K7EIE8|K7EIE8_HUMAN,tr|A0A087WT34|A0A087WT34_HUMAN,tr|A0A0A0MTS6|A0A0A0MTS6_HUMAN,tr|A0A087WZ12|A0A087WZ12_HUMAN" 6 1212.6218 1.69 126333 4602 3 1212.622421 405.2145 Methyl-CpG-binding domain protein 3 OS=Homo sapiens OX=9606 GN=MBD3 PE=1 SV=1 8.56 1440.1 - 2.50E+06 - - - 0.5369 - 1.602 0.186 - 105.6 1 2 1 0.0007 10 0 0 0 4.05E+07 2.39E+07 - - - 1.9898 0.9999 221125_WJC_METTL3_EV_vs_WT_F09.04603.04603.2 0.000479 22-Dec R.GSGSGQSPSYGR.H sp|Q86YZ3|HORN_HUMAN 1 1138.5003 999 126334 4603 2 1138.499706 570.2574 Hornerin OS=Homo sapiens OX=9606 GN=HRNR PE=1 SV=2 8.75 1440.2 - 1.61E+06 - - - -0.534 - 2.65 0.522 - 356.9 1 2 0 -0.0006 12 0 0 0 4.60E+08 0.00E+00 - - - 5.4605 0.9861 221125_WJC_METTL3_EV_vs_WT_F09.04610.04610.2 0.0268 18-Aug R.VR[166.11]YDSSNQVK[136.11].G "sp|O95983|MBD3_HUMAN,tr|A0A087X1H1|A0A087X1H1_HUMAN,tr|K7EIE8|K7EIE8_HUMAN,tr|A0A087WT34|A0A087WT34_HUMAN,tr|A0A0A0MTS6|A0A0A0MTS6_HUMAN,tr|A0A087WZ12|A0A087WZ12_HUMAN" 6 1212.6218 1.46 126341 4610 2 1212.622884 607.3182 Methyl-CpG-binding domain protein 3 OS=Homo sapiens OX=9606 GN=MBD3 PE=1 SV=1 8.56 1440.9 - 372675 - - - 0.9187 - 1.39 0.328 - 167.6 1 2 1 0.0011 10 0 0 0 3.99E+06 2.74E+06 - - - 2.3824 1 221125_WJC_METTL3_EV_vs_WT_F09.04611.04611.2 7.29E-08 22-Dec R.SDADENVSASDK.R "sp|Q92878|RAD50_HUMAN,tr|A0A494BZX8|A0A494BZX8_HUMAN,tr|H7C0V2|H7C0V2_HUMAN,tr|A0A1W2PQ90|A0A1W2PQ90_HUMAN" 4 1236.5106 1.07 126342 4611 2 1236.506054 619.2626 DNA repair protein RAD50 OS=Homo sapiens OX=9606 GN=RAD50 PE=1 SV=1 3.84 1441 - 287362 - - - -3.6797 - 2.48 0.706 - 575.3 1 2 0 -0.0046 12 0 0 0 4.79E+06 4.48E+06 - - - 6.6439 1 221125_WJC_METTL3_EV_vs_WT_F09.04612.04612.2 4.90E-09 22-Dec R.SDADENVSASDK[136.11].R "sp|Q92878|RAD50_HUMAN,tr|A0A494BZX8|A0A494BZX8_HUMAN,tr|H7C0V2|H7C0V2_HUMAN,tr|A0A1W2PQ90|A0A1W2PQ90_HUMAN" 4 1244.5248 1.07 126343 4612 2 1244.52261 623.2697 DNA repair protein RAD50 OS=Homo sapiens OX=9606 GN=RAD50 PE=1 SV=1 3.84 1441.1 - 248801 - - - -1.7629 - 2.676 0.733 - 554.3 1 2 0 -0.0022 12 0 0 0 4.79E+06 4.48E+06 - - - 7.0442 0.9913 221125_WJC_METTL3_EV_vs_WT_F09.04616.04616.2 0.000122 14-Oct T.GHWLNHGK[136.11].E sp|Q86U44|MTA70_HUMAN 1 955.4868 0.02 126345 4616 2 955.486655 478.7507 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 8.76 1441.7 - 4.17E+06 - - - -0.134 - 1.877 0.486 - 415 1 1 0 -0.0001 8 0 0 0 3.46E+07 2.13E+09 - - - 4.5296 0.9106 221125_WJC_METTL3_EV_vs_WT_F09.04617.04617.3 1.06 Jun-36 K.KDVDSAYMNK.V sp|P12035|K2C3_HUMAN 1 1169.5387 7.91 126346 4617 3 1169.53818 390.8535 "Keratin, type II cytoskeletal 3 OS=Homo sapiens OX=9606 GN=KRT3 PE=1 SV=3" 5.96 1441.8 - 3.08E+06 - - - -0.4224 - 1.229 0.123 - 70.7 1 2 0 -0.0005 10 0 0 0 4.11E+07 5.19E+06 - - - 0.5134 0.9892 221125_WJC_METTL3_EV_vs_WT_F09.04626.04626.2 1.37E-05 12-Oct G.HWLNHGK[136.11].E sp|Q86U44|MTA70_HUMAN 1 898.4653 0 126353 4626 2 898.464798 450.2399 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 8.76 1442.7 - 4.82E+06 - - - -0.581 - 2.01 0.41 - 312.4 1 1 0 -0.0005 7 0 0 0 1.10E+06 1.01E+09 - - - 4.2812 0.9973 221125_WJC_METTL3_EV_vs_WT_F09.04632.04632.3 0.00104 Nov-44 R.LTEQK[136.11]GEQQIQK[136.11].A sp|Q9Y5B9|SP16H_HUMAN 1 1444.7857 0.94 126359 4632 3 1444.785966 482.6025 FACT complex subunit SPT16 OS=Homo sapiens OX=9606 GN=SUPT16H PE=1 SV=1 6.14 1443.1 - 1.55E+06 - - - 0.2139 - 1.654 0.337 - 90.9 1 2 1 0.0003 12 0 0 0 4.21E+07 4.46E+07 - - - 3.6919 0.9999 221125_WJC_METTL3_EV_vs_WT_F09.04634.04634.3 6.62E-06 13/52 K.VAPAQPSEEGPGRK.D "sp|P23588|IF4B_HUMAN,tr|E7EX17|E7EX17_HUMAN" 2 1421.7263 2.98 126361 4634 3 1421.725549 474.916 Eukaryotic translation initiation factor 4B OS=Homo sapiens OX=9606 GN=EIF4B PE=1 SV=2 6.11 1443.2 - 682674 - - - -0.5226 - 2.318 0.41 - 200.1 1 2 0 -0.0007 14 0 0 0 2.93E+08 9.83E+07 - - - 5.3451 0.9997 221125_WJC_METTL3_EV_vs_WT_F09.04639.04639.2 0.000156 16-Nov R.TGHWLNHGK.E sp|Q86U44|MTA70_HUMAN 1 1048.5203 0.02 126364 4639 2 1048.519792 525.2674 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 8.47 1443.9 - 1.97E+06 - - - -0.4483 - 2.158 0.339 - 371.4 1 2 0 -0.0005 9 0 0 0 3.19E+08 1.47E+10 - - - 3.77 0.991 221125_WJC_METTL3_EV_vs_WT_F09.04642.04642.2 0.00977 22-Jul R.LTEQKGEQQIQK.A sp|Q9Y5B9|SP16H_HUMAN 1 1428.7573 1.02 126367 4642 2 1428.755637 715.3859 FACT complex subunit SPT16 OS=Homo sapiens OX=9606 GN=SUPT16H PE=1 SV=1 6.14 1444.3 - 210947 - - - -1.1339 - 1.706 0.316 - 153.9 1 2 1 -0.0016 12 0 0 0 3.39E+06 3.31E+06 - - - 2.7799 0.9989 221125_WJC_METTL3_EV_vs_WT_F09.04646.04646.3 0.0183 Aug-36 K.TSEDADELHK[136.11].L sp|Q9UKX7|NUP50_HUMAN 1 1151.5186 5.3 126369 4646 3 1151.515863 384.8468 Nuclear pore complex protein Nup50 OS=Homo sapiens OX=9606 GN=NUP50 PE=1 SV=2 4.31 1444.8 - 550652 - - - -2.3743 - 1.613 0.356 - 86.6 1 2 0 -0.0027 10 0 0 0 3.42E+07 6.46E+06 - - - 3.9045 0.9892 221125_WJC_METTL3_EV_vs_WT_F09.04651.04651.2 0.00963 22-Aug R.LTEQK[136.11]GEQQIQK[136.11].A sp|Q9Y5B9|SP16H_HUMAN 1 1444.7857 1.02 126374 4651 2 1444.786057 723.4001 FACT complex subunit SPT16 OS=Homo sapiens OX=9606 GN=SUPT16H PE=1 SV=1 6.14 1445.4 - 296050 - - - 0.2769 - 1.668 0.276 - 151.4 1 2 1 0.0004 12 0 0 0 3.39E+06 3.31E+06 - - - 2.4256 1 221125_WJC_METTL3_EV_vs_WT_F09.04657.04657.2 1.06E-05 17/20 K.K[136.11]ETEGDVTSVK[136.11].D sp|P50990|TCPQ_HUMAN 1 1207.6267 0.4 126378 4657 2 1207.623346 604.8206 T-complex protein 1 subunit theta OS=Homo sapiens OX=9606 GN=CCT8 PE=1 SV=4 4.68 1446.1 - 1.48E+06 - - - -2.7749 - 3.221 0.535 - 947.1 1 2 0 -0.0034 11 0 0 0 5.97E+07 1.48E+08 - - - 6.1558 0.9997 221125_WJC_METTL3_EV_vs_WT_F09.04673.04673.3 1.92E-05 Dec-40 K.KETEGDVTSVK.D sp|P50990|TCPQ_HUMAN 1 1191.5983 0.43 126387 4673 3 1191.594594 398.2067 T-complex protein 1 subunit theta OS=Homo sapiens OX=9606 GN=CCT8 PE=1 SV=4 4.68 1447.8 - 4.43E+06 - - - -3.1076 - 2.375 0.408 - 293.1 1 2 0 -0.0037 11 0 0 0 1.12E+08 2.62E+08 - - - 5.5451 0.9994 221125_WJC_METTL3_EV_vs_WT_F09.04677.04677.2 1.67E-05 17/20 K.KETEGDVTSVK.D sp|P50990|TCPQ_HUMAN 1 1191.5983 0.4 126389 4677 2 1191.594665 596.8064 T-complex protein 1 subunit theta OS=Homo sapiens OX=9606 GN=CCT8 PE=1 SV=4 4.68 1448.2 - 2.75E+06 - - - -3.048 - 2.694 0.419 - 927.6 1 2 0 -0.0036 11 0 0 0 5.97E+07 1.48E+08 - - - 4.8156 0.9975 221125_WJC_METTL3_EV_vs_WT_F09.04702.04702.2 1.34E-07 22-Dec R.NSTPSSSSSLQK[136.11].S "sp|Q9P0U3|SENP1_HUMAN,tr|F8VRZ8|F8VRZ8_HUMAN" 2 1229.5979 0.81 126399 4702 2 1229.595337 615.8062 Sentrin-specific protease 1 OS=Homo sapiens OX=9606 GN=SENP1 PE=1 SV=2 8.75 1451.3 - 1.05E+06 - - - -2.0926 - 2.145 0.168 - 478.2 1 2 0 -0.0026 12 0 0 0 2.57E+07 3.19E+07 - - - 2.289 0.9964 221125_WJC_METTL3_EV_vs_WT_F09.04703.04703.2 1.38E-05 14/22 R.NSTPSSSSSLQK.S "sp|Q9P0U3|SENP1_HUMAN,tr|F8VRZ8|F8VRZ8_HUMAN" 2 1221.5837 0.81 126400 4703 2 1221.578362 611.7991 Sentrin-specific protease 1 OS=Homo sapiens OX=9606 GN=SENP1 PE=1 SV=2 8.75 1451.4 - 1.27E+06 - - - -4.3779 - 1.894 0.39 - 432.1 1 2 0 -0.0053 12 0 0 0 2.57E+07 3.19E+07 - - - 3.6004 0.9992 221125_WJC_METTL3_EV_vs_WT_F09.04709.04709.2 1.84E-05 18-Nov R.KDNASNIYSK.N sp|Q8TBA6|GOGA5_HUMAN 1 1138.5619 2.15 126402 4709 2 1138.558442 570.2882 Golgin subfamily A member 5 OS=Homo sapiens OX=9606 GN=GOLGA5 PE=1 SV=3 8.5 1452.2 - 512477 - - - -2.995 - 2.265 0.389 - 351.3 1 2 0 -0.0034 10 0 0 0 2.35E+07 1.09E+07 - - - 4.1952 0.9999 221125_WJC_METTL3_EV_vs_WT_F09.04711.04711.3 6.80E-05 Dec-48 R.SSDGRPDSGGTLR.L "sp|P55196|AFAD_HUMAN,tr|J3KN01|J3KN01_HUMAN,tr|A0A804HJ20|A0A804HJ20_HUMAN,tr|Q5TIG5|Q5TIG5_HUMAN,tr|A8MQ02|A8MQ02_HUMAN" 5 1303.6117 1.19 126403 4711 3 1303.609009 435.5445 Afadin OS=Homo sapiens OX=9606 GN=AFDN PE=1 SV=3 5.68 1452.4 - 1.04E+06 - - - -2.0305 - 1.947 0.491 - 226.4 1 2 0 -0.0026 13 0 0 0 4.63E+07 3.89E+07 - - - 5.8199 1 221125_WJC_METTL3_EV_vs_WT_F09.04713.04713.3 1.91E-06 16/52 K.RPGVTGENSNEVAK.L "sp|Q7Z3K3|POGZ_HUMAN,tr|M0R2X2|M0R2X2_HUMAN" 2 1456.727 0.77 126405 4713 3 1456.726444 486.5829 Pogo transposable element with ZNF domain OS=Homo sapiens OX=9606 GN=POGZ PE=1 SV=2 6.14 1452.7 - 950507 - - - -0.3954 - 2.814 0.497 - 374.5 1 2 0 -0.0006 14 0 0 0 2.35E+07 3.08E+07 - - - 6.8304 0.9995 221125_WJC_METTL3_EV_vs_WT_F09.04718.04718.2 0.00378 14/26 K.VQTESSTGSVGSNR[166.11].V sp|Q9BRX2|PELO_HUMAN 1 1417.6673 0.79 126408 4718 2 1417.663961 709.8409 Protein pelota homolog OS=Homo sapiens OX=9606 GN=PELO PE=1 SV=2 5.97 1453.3 - 2.37E+06 - - - -2.3341 - 2.094 0.447 - 394.7 1 2 0 -0.0033 14 0 0 0 2.47E+07 3.15E+07 - - - 4.1962 0.9972 221125_WJC_METTL3_EV_vs_WT_F09.04719.04719.3 0.00169 Oct-48 R.SSDGR[166.11]PDSGGTLR[166.11].L "sp|P55196|AFAD_HUMAN,tr|J3KN01|J3KN01_HUMAN,tr|A0A804HJ20|A0A804HJ20_HUMAN,tr|Q5TIG5|Q5TIG5_HUMAN,tr|A8MQ02|A8MQ02_HUMAN" 5 1323.6282 1.18 126409 4719 3 1323.621852 442.2167 Afadin OS=Homo sapiens OX=9606 GN=AFDN PE=1 SV=3 5.68 1453.4 - 2.69E+06 - - - -4.7929 - 1.987 0.373 - 72.1 1 2 0 -0.0063 13 0 0 0 4.59E+07 3.89E+07 - - - 4.5585 0.9907 221125_WJC_METTL3_EV_vs_WT_F09.04720.04720.2 0.0202 20-Oct R.EK[136.11]LHGTVVEGR[166.11].K "sp|O43251|RFOX2_HUMAN,sp|Q9NWB1|RFOX1_HUMAN,tr|A0A6Q8PGE0|A0A6Q8PGE0_HUMAN,tr|A0A6Q8PH77|A0A6Q8PH77_HUMAN,tr|A0A286YEU2|A0A286YEU2_HUMAN,tr|A0A087X2B1|A0A087X2B1_HUMAN,tr|F8VR27|F8VR27_HUMAN,tr|B7Z1U7|B7Z1U7_HUMAN,tr|B0QYV1|B0QYV1_HUMAN,tr|A0A6Q8PHA3|A0A6Q8PHA3_HUMAN,tr|F8VZY7|F8VZY7_HUMAN,tr|B0QYY4|B0QYY4_HUMAN,tr|J3KNW3|J3KNW3_HUMAN,tr|F8VZG9|F8VZG9_HUMAN,tr|F8VRS4|F8VRS4_HUMAN,tr|A0A6Q8PFM4|A0A6Q8PFM4_HUMAN,tr|S4R469|S4R469_HUMAN,tr|A0A804HKG7|A0A804HKG7_HUMAN,tr|A0A0G2JRD1|A0A0G2JRD1_HUMAN,tr|A0A0G2JRA5|A0A0G2JRA5_HUMAN,tr|A0A804HJM2|A0A804HJM2_HUMAN,tr|I3L1D4|I3L1D4_HUMAN,tr|S4R3K7|S4R3K7_HUMAN" 23 1241.6847 1.11 126410 4720 2 1241.682015 621.8496 RNA binding protein fox-1 homolog 2 OS=Homo sapiens OX=9606 GN=RBFOX2 PE=1 SV=3 6.86 1453.5 - 554400 - - - -2.1664 - 2.069 0.326 - 376.2 1 2 1 -0.0027 11 0 0 0 1.10E+08 9.94E+07 - - - 3.4149 0.9995 221125_WJC_METTL3_EV_vs_WT_F09.04721.04721.2 0.00517 16-Dec K.KLNVTEQEK.L "sp|P06733|ENOA_HUMAN,tr|A0A2R8Y6G6|A0A2R8Y6G6_HUMAN,tr|K7EM90|K7EM90_HUMAN,tr|A0A2R8Y879|A0A2R8Y879_HUMAN,tr|A0A2R8Y6I8|A0A2R8Y6I8_HUMAN,tr|A0A2R8YEM5|A0A2R8YEM5_HUMAN" 6 1087.5873 1.54 126411 4721 2 1087.58548 544.8009 Alpha-enolase OS=Homo sapiens OX=9606 GN=ENO1 PE=1 SV=2 6.14 1453.6 - 417559 - - - -1.7093 - 2.093 0.341 - 529.1 1 2 0 -0.0019 9 0 0 0 8.48E+06 5.51E+06 - - - 3.6958 0.9892 221125_WJC_METTL3_EV_vs_WT_F09.04732.04732.2 0.00122 20-Nov R.EKLHGTVVEGR.K "sp|O43251|RFOX2_HUMAN,sp|Q9NWB1|RFOX1_HUMAN,tr|A0A6Q8PGE0|A0A6Q8PGE0_HUMAN,tr|A0A6Q8PH77|A0A6Q8PH77_HUMAN,tr|A0A286YEU2|A0A286YEU2_HUMAN,tr|A0A087X2B1|A0A087X2B1_HUMAN,tr|F8VR27|F8VR27_HUMAN,tr|B7Z1U7|B7Z1U7_HUMAN,tr|B0QYV1|B0QYV1_HUMAN,tr|A0A6Q8PHA3|A0A6Q8PHA3_HUMAN,tr|F8VZY7|F8VZY7_HUMAN,tr|B0QYY4|B0QYY4_HUMAN,tr|J3KNW3|J3KNW3_HUMAN,tr|F8VZG9|F8VZG9_HUMAN,tr|F8VRS4|F8VRS4_HUMAN,tr|A0A6Q8PFM4|A0A6Q8PFM4_HUMAN,tr|S4R469|S4R469_HUMAN,tr|A0A804HKG7|A0A804HKG7_HUMAN,tr|A0A0G2JRD1|A0A0G2JRD1_HUMAN,tr|A0A0G2JRA5|A0A0G2JRA5_HUMAN,tr|A0A804HJM2|A0A804HJM2_HUMAN,tr|I3L1D4|I3L1D4_HUMAN,tr|S4R3K7|S4R3K7_HUMAN" 23 1223.6622 1.11 126416 4732 2 1223.659033 612.8384 RNA binding protein fox-1 homolog 2 OS=Homo sapiens OX=9606 GN=RBFOX2 PE=1 SV=3 6.86 1455.1 - 1.26E+06 - - - -2.6167 - 1.815 0.402 - 315.6 1 2 1 -0.0032 11 0 0 0 1.10E+08 9.94E+07 - - - 3.6217 0.9998 221125_WJC_METTL3_EV_vs_WT_F09.04749.04749.2 0.000265 26-Oct R.GSGGGSSGGSIGGR.G sp|P04264|K2C1_HUMAN 1 1091.4956 15.4 126427 4749 2 1091.495144 546.7551 "Keratin, type II cytoskeletal 1 OS=Homo sapiens OX=9606 GN=KRT1 PE=1 SV=6" 9.75 1457.1 - 282436 - - - -0.3839 - 1.964 0.465 - 243 1 2 0 -0.0004 14 0 0 0 5.71E+06 3.71E+05 - - - 4.1692 0.983 221125_WJC_METTL3_EV_vs_WT_F09.04756.04756.2 0.0145 18-Dec E.KLHGTVVEGR.K "sp|O43251|RFOX2_HUMAN,sp|Q9NWB1|RFOX1_HUMAN,tr|A0A6Q8PGE0|A0A6Q8PGE0_HUMAN,tr|A0A6Q8PH77|A0A6Q8PH77_HUMAN,tr|A0A286YEU2|A0A286YEU2_HUMAN,tr|A0A087X2B1|A0A087X2B1_HUMAN,tr|F8VR27|F8VR27_HUMAN,tr|B7Z1U7|B7Z1U7_HUMAN,tr|B0QYV1|B0QYV1_HUMAN,tr|A0A6Q8PHA3|A0A6Q8PHA3_HUMAN,tr|F8VZY7|F8VZY7_HUMAN,tr|B0QYY4|B0QYY4_HUMAN,tr|J3KNW3|J3KNW3_HUMAN,tr|F8VZG9|F8VZG9_HUMAN,tr|F8VRS4|F8VRS4_HUMAN,tr|A0A6Q8PFM4|A0A6Q8PFM4_HUMAN,tr|S4R469|S4R469_HUMAN,tr|A0A804HKG7|A0A804HKG7_HUMAN,tr|A0A0G2JRD1|A0A0G2JRD1_HUMAN,tr|A0A0G2JRA5|A0A0G2JRA5_HUMAN,tr|A0A804HJM2|A0A804HJM2_HUMAN,tr|I3L1D4|I3L1D4_HUMAN,tr|S4R3K7|S4R3K7_HUMAN" 23 1094.6196 1.23 126431 4756 2 1094.618493 548.3171 RNA binding protein fox-1 homolog 2 OS=Homo sapiens OX=9606 GN=RBFOX2 PE=1 SV=3 8.75 1457.8 - 404303 - - - -1.0497 - 2.098 0.374 - 583.2 1 1 0 -0.0011 10 0 0 0 6.90E+06 5.62E+06 - - - 3.8713 0.995 221125_WJC_METTL3_EV_vs_WT_F09.04771.04771.2 0.47 16-Jun K.LHGTVVEGR.K "sp|O43251|RFOX2_HUMAN,sp|Q9NWB1|RFOX1_HUMAN,tr|A0A6Q8PGE0|A0A6Q8PGE0_HUMAN,tr|A0A6Q8PH77|A0A6Q8PH77_HUMAN,tr|A0A286YEU2|A0A286YEU2_HUMAN,tr|A0A087X2B1|A0A087X2B1_HUMAN,tr|F8VR27|F8VR27_HUMAN,tr|B7Z1U7|B7Z1U7_HUMAN,tr|B0QYV1|B0QYV1_HUMAN,tr|A0A6Q8PHA3|A0A6Q8PHA3_HUMAN,tr|F8VZY7|F8VZY7_HUMAN,tr|B0QYY4|B0QYY4_HUMAN,tr|J3KNW3|J3KNW3_HUMAN,tr|F8VZG9|F8VZG9_HUMAN,tr|F8VRS4|F8VRS4_HUMAN,tr|A0A6Q8PFM4|A0A6Q8PFM4_HUMAN,tr|S4R469|S4R469_HUMAN,tr|A0A804HKG7|A0A804HKG7_HUMAN,tr|A0A0G2JRD1|A0A0G2JRD1_HUMAN,tr|A0A0G2JRA5|A0A0G2JRA5_HUMAN,tr|A0A804HJM2|A0A804HJM2_HUMAN,tr|I3L1D4|I3L1D4_HUMAN,tr|S4R3K7|S4R3K7_HUMAN" 23 966.5247 1.37 126442 4771 2 966.525161 484.2696 RNA binding protein fox-1 homolog 2 OS=Homo sapiens OX=9606 GN=RBFOX2 PE=1 SV=3 6.75 1459.6 - 426443 - - - 0.4987 - 1.272 0.221 - 124.7 3 2 0 0.0005 9 0 0 0 7.08E+06 5.17E+06 - - - 1.1561 0.8834 221125_WJC_METTL3_EV_vs_WT_F09.04776.04776.2 0.000949 24-Jun Y.ASPVSQSPQTSSK.Q "sp|P43694|GATA4_HUMAN,tr|B3KUF4|B3KUF4_HUMAN,tr|A0A087WZ09|A0A087WZ09_HUMAN" 3 1302.6416 3.24 126444 4776 2 1302.638423 652.3281 Transcription factor GATA-4 OS=Homo sapiens OX=9606 GN=GATA4 PE=1 SV=2 8.8 1460.3 - 163538 - - - -2.4074 - 1.187 0.425 - 78.1 1 1 0 -0.0031 13 0 0 0 3.57E+06 1.10E+06 - - - 2.619 0.9991 221125_WJC_METTL3_EV_vs_WT_F09.04780.04780.2 4.42E-06 16-Oct R.TGHWLNHGK[136.11].E sp|Q86U44|MTA70_HUMAN 1 1056.5345 0.02 126446 4780 2 1056.532391 529.2745 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 8.47 1460.9 - 1.67E+07 - - - -1.9602 - 1.945 0.306 - 311.9 1 2 0 -0.0021 9 0 0 0 3.19E+08 1.47E+10 - - - 3.2251 0.9999 221125_WJC_METTL3_EV_vs_WT_F09.04783.04783.3 0.000183 13/48 R.SSVGPSKPVSQPR.R sp|Q9Y657|SPIN1_HUMAN 1 1324.7099 2.27 126448 4783 3 1324.707888 442.5772 Spindlin-1 OS=Homo sapiens OX=9606 GN=SPIN1 PE=1 SV=3 11 1461.2 - 1.20E+06 - - - -1.5286 - 2.623 0.43 - 204.7 1 2 0 -0.002 13 0 0 0 2.15E+08 9.47E+07 - - - 5.9481 0.9999 221125_WJC_METTL3_EV_vs_WT_F09.04789.04789.2 8.53E-05 24-Aug K.DADSQNPDAPEGK[136.11].R "sp|P53621|COPA_HUMAN,tr|A0A3B3ISC6|A0A3B3ISC6_HUMAN,tr|A0A3B3ITV3|A0A3B3ITV3_HUMAN,tr|A0A3B3IS84|A0A3B3IS84_HUMAN,tr|A0A3B3IU89|A0A3B3IU89_HUMAN,tr|A0A3B3ISK1|A0A3B3ISK1_HUMAN,tr|A0A3B3IT15|A0A3B3IT15_HUMAN" 7 1350.5779 0.29 126454 4789 2 1350.577147 676.2962 Coatomer subunit alpha OS=Homo sapiens OX=9606 GN=COPA PE=1 SV=2 3.84 1461.9 - 161726 - - - -0.5598 - 1.832 0.557 - 212.6 1 2 0 -0.0008 13 0 0 0 7.88E+05 2.69E+06 - - - 4.7086 0.9999 221125_WJC_METTL3_EV_vs_WT_F09.04790.04790.2 1.21E-05 13/24 K.NGGGVGGGELDK[136.11]K[136.11].D sp|Q9H7S9|ZN703_HUMAN 1 1202.6226 1.4 126455 4790 2 1202.621904 602.3186 Zinc finger protein 703 OS=Homo sapiens OX=9606 GN=ZNF703 PE=1 SV=1 6.07 1462 - 111403 - - - -0.5912 - 2.446 0.515 - 619.5 1 2 0 -0.0007 13 0 0 0 2.89E+07 2.06E+07 - - - 5.1402 1 221125_WJC_METTL3_EV_vs_WT_F09.04793.04793.3 0.0135 19/48 K.NGGGVGGGELDKK.D sp|Q9H7S9|ZN703_HUMAN 1 1186.5942 1.54 126456 4793 3 1186.593348 396.5387 Zinc finger protein 703 OS=Homo sapiens OX=9606 GN=ZNF703 PE=1 SV=1 6.07 1462.4 - 2.58E+06 - - - -0.7307 - 2.978 0.534 - 590.5 1 2 0 -0.0009 13 0 0 0 1.64E+08 1.06E+08 - - - 7.452 1 221125_WJC_METTL3_EV_vs_WT_F09.04794.04794.3 0.00098 13/48 R.SSVGPSK[136.11]PVSQPR[166.11].R sp|Q9Y657|SPIN1_HUMAN 1 1342.7324 2.27 126457 4794 3 1342.73079 448.5847 Spindlin-1 OS=Homo sapiens OX=9606 GN=SPIN1 PE=1 SV=3 11 1462.5 - 1.59E+06 - - - -1.1864 - 2.529 0.45 - 190.4 1 2 0 -0.0016 13 0 0 0 2.14E+08 9.42E+07 - - - 6.0722 0.9984 221125_WJC_METTL3_EV_vs_WT_F09.04795.04795.2 0.000273 14-Oct K.ADKDYHFK.V "sp|P06748|NPM_HUMAN,tr|A0A7I2V4G8|A0A7I2V4G8_HUMAN,tr|A0A7I2YQC0|A0A7I2YQC0_HUMAN,tr|A0A7I2V433|A0A7I2V433_HUMAN,tr|A0A7I2V579|A0A7I2V579_HUMAN,tr|A0A7I2V2X9|A0A7I2V2X9_HUMAN,tr|A0A7I2V3G5|A0A7I2V3G5_HUMAN,tr|A0A7I2V5S2|A0A7I2V5S2_HUMAN,tr|A0A7I2V3U2|A0A7I2V3U2_HUMAN" 9 1022.4821 0.78 126458 4795 2 1022.481773 512.2483 Nucleophosmin OS=Homo sapiens OX=9606 GN=NPM1 PE=1 SV=2 6.79 1462.6 - 741882 - - - -0.3638 - 1.898 0.492 - 350.4 1 2 1 -0.0004 8 0 0 0 2.84E+07 3.63E+07 - - - 4.6074 0.9945 221125_WJC_METTL3_EV_vs_WT_F09.04801.04801.3 3.42E-05 Dec-40 F.SLEDPQTHSNR.L sp|P08238|HS90B_HUMAN 1 1282.5902 0.33 126462 4801 3 1282.5907 428.5373 Heat shock protein HSP 90-beta OS=Homo sapiens OX=9606 GN=HSP90AB1 PE=1 SV=4 5.3 1463.4 - 1.00E+06 - - - 0.3961 - 1.953 0.485 - 152.3 1 1 0 0.0005 11 0 0 0 2.62E+07 7.96E+07 - - - 5.8487 1 221125_WJC_METTL3_EV_vs_WT_F09.04802.04802.2 5.64E-07 13/24 K.NGGGVGGGELDKK.D sp|Q9H7S9|ZN703_HUMAN 1 1186.5942 1.42 126463 4802 2 1186.595076 594.3044 Zinc finger protein 703 OS=Homo sapiens OX=9606 GN=ZNF703 PE=1 SV=1 6.07 1463.5 - 933079 - - - 0.7256 - 2.803 0.583 - 556.3 1 2 0 0.0009 13 0 0 0 2.92E+07 2.06E+07 - - - 5.9921 0.9995 221125_WJC_METTL3_EV_vs_WT_F09.04808.04808.3 0.00628 Jul-44 R.VLEENHVEHQPR.F sp|Q9H4L5|OSBL3_HUMAN 1 1485.7324 0.44 126469 4808 3 1485.732265 496.2514 Oxysterol-binding protein-related protein 3 OS=Homo sapiens OX=9606 GN=OSBPL3 PE=1 SV=1 5.32 1464.3 - 139856 - - - -0.1178 - 1.439 0.384 - 52.2 1 2 0 -0.0002 12 0 0 0 1.34E+06 3.02E+06 - - - 3.83 0.9994 221125_WJC_METTL3_EV_vs_WT_F09.04810.04810.3 0.000896 Aug-44 R.VLEENHVEHQPR[166.11].F sp|Q9H4L5|OSBL3_HUMAN 1 1495.7407 1.61 126471 4810 3 1495.739644 499.5875 Oxysterol-binding protein-related protein 3 OS=Homo sapiens OX=9606 GN=OSBPL3 PE=1 SV=1 5.32 1464.5 - 74253.5 - - - -0.7127 - 1.551 0.35 - 74.1 1 2 0 -0.0011 12 0 0 0 1.21E+06 7.50E+05 - - - 3.6584 0.9996 221125_WJC_METTL3_EV_vs_WT_F09.04816.04816.3 0.00192 13/36 K.YTPPPHHIGK[136.11].G sp|O43920|NDUS5_HUMAN 1 1153.6124 1.42 126475 4816 3 1153.612669 385.5447 NADH dehydrogenase [ubiquinone] iron-sulfur protein 5 OS=Homo sapiens OX=9606 GN=NDUFS5 PE=1 SV=3 8.61 1465.2 - 1.07E+06 - - - 0.2523 - 1.864 0.319 - 277.2 1 2 0 0.0003 10 0 0 0 2.60E+07 1.83E+07 - - - 3.9151 0.9997 221125_WJC_METTL3_EV_vs_WT_F09.04821.04821.2 0.000846 24-Aug R.SSVGPSKPVSQPR.R sp|Q9Y657|SPIN1_HUMAN 1 1324.7099 2.62 126480 4821 2 1324.709624 663.3622 Spindlin-1 OS=Homo sapiens OX=9606 GN=SPIN1 PE=1 SV=3 11 1465.7 - 330532 - - - -0.2182 - 1.766 0.422 - 139.1 1 2 0 -0.0003 13 0 0 0 1.45E+07 5.53E+06 - - - 3.6174 0.9995 221125_WJC_METTL3_EV_vs_WT_F09.04823.04823.3 0.000101 Nov-48 K.YTKQDGEC[160.03]GTLSK.G sp|Q5D862|FILA2_HUMAN 1 1485.677 7.88 126482 4823 3 1485.677734 496.2329 Filaggrin-2 OS=Homo sapiens OX=9606 GN=FLG2 PE=1 SV=1 6.06 1465.9 - 242849 - - - 0.5216 - 1.958 0.435 - 90.9 1 2 1 0.0008 13 0 0 0 3.83E+07 4.86E+06 - - - 5.2114 0.9852 221125_WJC_METTL3_EV_vs_WT_F09.04824.04824.2 0.000123 18-Oct V.GPSKPVSQPR.R sp|Q9Y657|SPIN1_HUMAN 1 1051.5774 1.94 126483 4824 2 1051.578475 526.796 Spindlin-1 OS=Homo sapiens OX=9606 GN=SPIN1 PE=1 SV=3 11 1466.1 - 225115 - - - 0.9814 - 1.899 0.449 - 291.6 1 1 0 0.001 10 0 0 0 7.02E+06 3.63E+06 - - - 4.1471 0.9996 221125_WJC_METTL3_EV_vs_WT_F09.04828.04828.3 0.000258 Oct-40 R.EKLHGTVVEGR.K "sp|O43251|RFOX2_HUMAN,sp|Q9NWB1|RFOX1_HUMAN,tr|A0A6Q8PGE0|A0A6Q8PGE0_HUMAN,tr|A0A6Q8PH77|A0A6Q8PH77_HUMAN,tr|A0A286YEU2|A0A286YEU2_HUMAN,tr|A0A087X2B1|A0A087X2B1_HUMAN,tr|F8VR27|F8VR27_HUMAN,tr|B7Z1U7|B7Z1U7_HUMAN,tr|B0QYV1|B0QYV1_HUMAN,tr|A0A6Q8PHA3|A0A6Q8PHA3_HUMAN,tr|F8VZY7|F8VZY7_HUMAN,tr|B0QYY4|B0QYY4_HUMAN,tr|J3KNW3|J3KNW3_HUMAN,tr|F8VZG9|F8VZG9_HUMAN,tr|F8VRS4|F8VRS4_HUMAN,tr|A0A6Q8PFM4|A0A6Q8PFM4_HUMAN,tr|S4R469|S4R469_HUMAN,tr|A0A804HKG7|A0A804HKG7_HUMAN,tr|A0A0G2JRD1|A0A0G2JRD1_HUMAN,tr|A0A0G2JRA5|A0A0G2JRA5_HUMAN,tr|A0A804HJM2|A0A804HJM2_HUMAN,tr|I3L1D4|I3L1D4_HUMAN,tr|S4R3K7|S4R3K7_HUMAN" 23 1223.6622 1.12 126486 4828 3 1223.662361 408.8947 RNA binding protein fox-1 homolog 2 OS=Homo sapiens OX=9606 GN=RBFOX2 PE=1 SV=3 6.86 1466.6 - 2.98E+06 - - - 0.103 - 2.127 0.412 - 155.1 1 2 1 0.0001 11 0 0 0 2.03E+09 1.81E+09 - - - 5.2774 0.9997 221125_WJC_METTL3_EV_vs_WT_F09.04832.04832.3 0.000361 13/36 K.YTPPPHHIGK.G sp|O43920|NDUS5_HUMAN 1 1145.5982 1.27 126489 4832 3 1145.598203 382.8733 NADH dehydrogenase [ubiquinone] iron-sulfur protein 5 OS=Homo sapiens OX=9606 GN=NDUFS5 PE=1 SV=3 8.61 1467 - 2.03E+06 - - - 0.0218 - 2.086 0.319 - 280.4 1 2 0 0 10 0 0 0 2.65E+07 2.09E+07 - - - 4.2438 0.7988 221125_WJC_METTL3_EV_vs_WT_F09.04836.04836.2 0.0876 20-Jun G.GGVGGGELDK[136.11]K[136.11].D sp|Q9H7S9|ZN703_HUMAN 1 1031.5582 1.54 126493 4836 2 1031.557585 516.7864 Zinc finger protein 703 OS=Homo sapiens OX=9606 GN=ZNF703 PE=1 SV=1 6.07 1467.5 - 117224 - - - -0.6195 - 1.059 0.281 - 88.2 1 1 0 -0.0006 11 0 0 0 1.57E+06 1.02E+06 - - - 1.2713 1 221125_WJC_METTL3_EV_vs_WT_F09.04841.04841.3 1.79E-05 23/52 K.EESAASGGAAYTK[136.11]R[166.11].Y "sp|Q9Y2W1|TR150_HUMAN,tr|A0A3B3ITZ9|A0A3B3ITZ9_HUMAN" 2 1414.6807 2.63 126496 4841 3 1414.680954 472.5675 Thyroid hormone receptor-associated protein 3 OS=Homo sapiens OX=9606 GN=THRAP3 PE=1 SV=2 6.24 1468.2 - 1.90E+06 - - - 0.1499 - 3.573 0.57 - 1299.8 1 2 0 0.0002 14 0 0 0 1.20E+09 4.58E+08 - - - 8.279 0.9845 221125_WJC_METTL3_EV_vs_WT_F09.04843.04843.3 4 Sep-44 K.GSLGEERNPTSK.Y "sp|Q86U86|PB1_HUMAN,tr|H0Y5B5|H0Y5B5_HUMAN,tr|E7EVG2|E7EVG2_HUMAN" 3 1273.6262 1.27 126498 4843 3 1273.626231 425.5494 Protein polybromo-1 OS=Homo sapiens OX=9606 GN=PBRM1 PE=1 SV=1 6.14 1468.3 - 1.16E+06 - - - -0.0094 - 1.634 0.231 - 97.8 1 2 1 0 12 0 0 0 1.43E+07 1.13E+07 - - - 2.4765 0.9839 221125_WJC_METTL3_EV_vs_WT_F09.04846.04846.2 1.92 18-Jul R.R[166.11]LSYNTASNK[136.11].T sp|P49207|RL34_HUMAN 1 1170.6112 1.68 126501 4846 2 1170.610823 586.3129 60S ribosomal protein L34 OS=Homo sapiens OX=9606 GN=RPL34 PE=1 SV=3 9.99 1468.7 - 183262 - - - -0.3272 - 1.45 0.059 - 123.8 3 2 0 -0.0004 10 0 0 0 5.58E+06 3.31E+06 - - - 0.3007 1 221125_WJC_METTL3_EV_vs_WT_F09.04847.04847.2 4.39E-08 26-Nov K.EESAASGGAAYTKR.Y "sp|Q9Y2W1|TR150_HUMAN,tr|A0A3B3ITZ9|A0A3B3ITZ9_HUMAN" 2 1396.6583 2.53 126502 4847 2 1396.658646 699.3364 Thyroid hormone receptor-associated protein 3 OS=Homo sapiens OX=9606 GN=THRAP3 PE=1 SV=2 6.24 1468.9 - 160417 - - - 0.2678 - 2.629 0.596 - 343.7 1 2 0 0.0004 14 0 0 0 7.16E+07 2.83E+07 - - - 5.8686 0.9861 221125_WJC_METTL3_EV_vs_WT_F09.04850.04850.2 0.0349 24-Jun K.YTKQDGEC[160.03]GTLSK.G sp|Q5D862|FILA2_HUMAN 1 1485.677 999 126505 4850 2 1485.677252 743.8458 Filaggrin-2 OS=Homo sapiens OX=9606 GN=FLG2 PE=1 SV=1 6.06 1469.3 - 70333.2 - - - 0.1972 - 1.338 0.325 - 80.8 1 2 1 0.0003 13 0 0 0 1.71E+06 0.00E+00 - - - 2.1887 0.9808 221125_WJC_METTL3_EV_vs_WT_F09.04854.04854.3 0.00131 13/48 K.NGGGVGGGELDKK[136.11].D sp|Q9H7S9|ZN703_HUMAN 1 1194.6084 - 126508 4854 3 1194.601974 399.2101 Zinc finger protein 703 OS=Homo sapiens OX=9606 GN=ZNF703 PE=1 SV=1 6.07 1469.7 - 206035 - - - -5.3917 - 1.796 0.291 - 210.9 1 2 0 -0.0064 13 0 0 0 - - - - - 3.3702 1 221125_WJC_METTL3_EV_vs_WT_F09.04857.04857.3 8.25E-07 14/32 K.LHEDLC[160.03]EK[136.11]R[166.11].T sp|Q8N1G4|LRC47_HUMAN 1 1216.5989 0.82 126511 4857 3 1216.597591 406.5403 Leucine-rich repeat-containing protein 47 OS=Homo sapiens OX=9606 GN=LRRC47 PE=1 SV=1 5.45 1470 - 530634 - - - -1.0981 - 2.666 0.53 - 268.3 1 2 0 -0.0013 9 0 0 0 4.94E+06 6.05E+06 - - - 7.4039 0.9998 221125_WJC_METTL3_EV_vs_WT_F09.04858.04858.2 3.52E-08 14/26 K.EESAASGGAAYTK[136.11]R[166.11].Y "sp|Q9Y2W1|TR150_HUMAN,tr|A0A3B3ITZ9|A0A3B3ITZ9_HUMAN" 2 1414.6807 2.53 126512 4858 2 1414.681053 708.3476 Thyroid hormone receptor-associated protein 3 OS=Homo sapiens OX=9606 GN=THRAP3 PE=1 SV=2 6.24 1470.2 - 356281 - - - 0.2198 - 2.641 0.387 - 625 1 2 0 0.0003 14 0 0 0 7.16E+07 2.83E+07 - - - 4.3364 0.9999 221125_WJC_METTL3_EV_vs_WT_F09.04865.04865.3 0.176 13/44 R.GSPSTVSSSYKR.S "sp|P07197|NFM_HUMAN,tr|E7ESP9|E7ESP9_HUMAN,tr|E7EMV2|E7EMV2_HUMAN" 3 1254.6204 0.59 126517 4865 3 1254.619633 419.2141 Neurofilament medium polypeptide OS=Homo sapiens OX=9606 GN=NEFM PE=1 SV=3 9.99 1471 - 1.12E+06 - - - -0.6353 - 2.546 0.407 - 272.8 1 2 0 -0.0008 12 0 0 0 3.33E+07 5.65E+07 - - - 5.6678 0.9992 221125_WJC_METTL3_EV_vs_WT_F09.04866.04866.3 0.0249 Oct-48 R.VDPDSQQNHSEIK.L sp|Q9BXS6|NUSAP_HUMAN 1 1495.6903 1.53 126518 4866 3 1495.690247 499.5707 Nucleolar and spindle-associated protein 1 OS=Homo sapiens OX=9606 GN=NUSAP1 PE=1 SV=1 4.54 1471.2 - 438872 - - - -0.0354 - 1.523 0.343 - 109.7 1 2 0 -0.0001 13 0 0 0 1.03E+07 6.73E+06 - - - 3.5047 0.9992 221125_WJC_METTL3_EV_vs_WT_F09.04870.04870.2 1.64E-05 20-Sep K.QQTNNQTEVVK.L "sp|Q5BKZ1|ZN326_HUMAN,tr|A0A0A0MRN4|A0A0A0MRN4_HUMAN" 2 1287.6419 1.87 126522 4870 2 1287.642881 644.8282 DBIRD complex subunit ZNF326 OS=Homo sapiens OX=9606 GN=ZNF326 PE=1 SV=2 6 1471.7 - 234087 - - - 0.7673 - 2.03 0.248 - 313.4 1 2 0 0.001 11 0 0 0 3.85E+06 2.05E+06 - - - 2.7878 0.8851 221125_WJC_METTL3_EV_vs_WT_F09.04871.04871.3 0.0333 Jun-36 K.SEPHQVDVSR[166.11].L sp|O75529|TAF5L_HUMAN 1 1162.5606 32.52 126523 4871 3 1162.557075 388.5275 TAF5-like RNA polymerase II p300\CBP-associated factor-associated factor 65 kDa subunit 5L OS=Homo sapiens OX=9606 GN=TAF5L PE=1 SV=1 5.3 1471.8 - 146926 - - - -3.0493 - 1.449 0.181 - 42.1 14 2 0 -0.0035 10 0 0 0 2.28E+08 7.02E+06 - - - 1.1097 0.9866 221125_WJC_METTL3_EV_vs_WT_F09.04872.04872.2 0.337 13/24 E.ESAASGGAAYTKR.Y "sp|Q9Y2W1|TR150_HUMAN,tr|A0A3B3ITZ9|A0A3B3ITZ9_HUMAN" 2 1267.6157 2.24 126524 4872 2 1267.616075 634.8151 Thyroid hormone receptor-associated protein 3 OS=Homo sapiens OX=9606 GN=THRAP3 PE=1 SV=2 8.69 1471.9 - 141037 - - - 0.3124 - 2.37 0.368 - 560.1 1 1 0 0.0004 13 0 0 0 9.81E+06 4.37E+06 - - - 3.9736 1 221125_WJC_METTL3_EV_vs_WT_F09.04880.04880.3 0.000295 17/52 K.EESAASGGAAYTKR[166.11].Y "sp|Q9Y2W1|TR150_HUMAN,tr|A0A3B3ITZ9|A0A3B3ITZ9_HUMAN" 2 1406.6665 - 126530 4880 3 1406.666595 469.8961 Thyroid hormone receptor-associated protein 3 OS=Homo sapiens OX=9606 GN=THRAP3 PE=1 SV=2 6.24 1472.8 - 670990 - - - 0.0377 - 2.798 0.487 - 522.9 1 2 0 0.0001 14 0 0 0 - - - - - 6.7039 0.9919 221125_WJC_METTL3_EV_vs_WT_F09.04881.04881.2 3.75E-06 15/20 S.AASGGAAYTKR.Y "sp|Q9Y2W1|TR150_HUMAN,tr|A0A3B3ITZ9|A0A3B3ITZ9_HUMAN" 2 1051.5411 2.05 126531 4881 2 1051.539385 526.7778 Thyroid hormone receptor-associated protein 3 OS=Homo sapiens OX=9606 GN=THRAP3 PE=1 SV=2 9.99 1472.9 - 620212 - - - -1.59 - 2.532 0.56 - 962.5 1 1 0 -0.0017 11 0 0 0 7.33E+06 3.57E+06 - - - 5.6898 0.8465 221125_WJC_METTL3_EV_vs_WT_F09.04883.04883.2 1.30E-05 13/20 S.AASGGAAYTK[136.11]R[166.11].Y "sp|Q9Y2W1|TR150_HUMAN,tr|A0A3B3ITZ9|A0A3B3ITZ9_HUMAN" 2 1069.5635 2.45 126533 4883 2 1069.557203 535.789 Thyroid hormone receptor-associated protein 3 OS=Homo sapiens OX=9606 GN=THRAP3 PE=1 SV=2 9.99 1473.2 - 269141 - - - -5.9127 - 2.406 0.579 - 722.8 1 1 0 -0.0063 11 0 0 0 7.33E+06 3.00E+06 - - - 5.6906 0.9999 221125_WJC_METTL3_EV_vs_WT_F09.04892.04892.3 0.000638 Nov-44 R.TSNEVTVETDKK.T "sp|Q9NRY5|F1142_HUMAN,tr|E7ESJ7|E7ESJ7_HUMAN" 2 1349.6674 1.01 126539 4892 3 1349.66625 450.8964 Protein FAM114A2 OS=Homo sapiens OX=9606 GN=FAM114A2 PE=1 SV=4 4.68 1474.1 - 1.05E+06 - - - -0.881 - 2.218 0.402 - 185.2 1 2 0 -0.0012 12 0 0 0 4.91E+07 4.84E+07 - - - 5.2296 0.9994 221125_WJC_METTL3_EV_vs_WT_F09.04897.04897.3 0.0208 Nov-36 R.LHEADATLKR.E sp|Q8TBA6|GOGA5_HUMAN 1 1152.6251 2.33 126544 4897 3 1152.624116 385.2157 Golgin subfamily A member 5 OS=Homo sapiens OX=9606 GN=GOLGA5 PE=1 SV=3 6.75 1474.6 - 437078 - - - -0.8719 - 1.904 0.293 - 175.8 1 2 0 -0.001 10 0 0 0 9.21E+06 3.96E+06 - - - 3.687 0.9998 221125_WJC_METTL3_EV_vs_WT_F09.04898.04898.2 2.10E-06 18-Sep K.HNSVEDSVTK.S sp|O60563|CCNT1_HUMAN 1 1114.5255 0.46 126545 4898 2 1114.526675 558.27 Cyclin-T1 OS=Homo sapiens OX=9606 GN=CCNT1 PE=1 SV=1 5.32 1474.7 - 291565 - - - 1.0839 - 1.775 0.562 - 176.6 1 2 0 0.0012 10 0 0 0 2.94E+06 6.43E+06 - - - 4.7932 0.9968 221125_WJC_METTL3_EV_vs_WT_F09.04901.04901.3 0.0416 Nov-44 R.TSNEVTVETDK[136.11]K[136.11].T "sp|Q9NRY5|F1142_HUMAN,tr|E7ESJ7|E7ESJ7_HUMAN" 2 1365.6958 1.01 126546 4901 3 1365.696385 456.2392 Protein FAM114A2 OS=Homo sapiens OX=9606 GN=FAM114A2 PE=1 SV=4 4.68 1475.1 - 3.37E+06 - - - 0.3998 - 2.081 0.174 - 187.8 1 2 0 0.0005 12 0 0 0 4.91E+07 4.86E+07 - - - 2.5111 0.9426 221125_WJC_METTL3_EV_vs_WT_F09.04902.04902.2 0.151 24-May R.SSVGPSK[136.11]PVSQPR[166.11].R sp|Q9Y657|SPIN1_HUMAN 1 1342.7324 2.62 126547 4902 2 1342.727849 672.3735 Spindlin-1 OS=Homo sapiens OX=9606 GN=SPIN1 PE=1 SV=3 11 1475.2 - 295875 - - - -3.3767 - 1.256 0.151 - 46.9 2 2 0 -0.0045 13 0 0 0 1.45E+07 5.53E+06 - - - 0.6054 0.9997 221125_WJC_METTL3_EV_vs_WT_F09.04905.04905.2 0.000142 18-Aug K.NC[160.03]SETQYESK[136.11].V sp|P61981|1433G_HUMAN 1 1252.5121 1.08 126550 4905 2 1252.509481 627.2633 14-3-3 protein gamma OS=Homo sapiens OX=9606 GN=YWHAG PE=1 SV=2 4.53 1475.6 - 163260 - - - -2.1157 - 1.744 0.58 - 259.4 1 2 0 -0.0027 10 0 0 0 3.00E+06 2.78E+06 - - - 4.8765 0.9999 221125_WJC_METTL3_EV_vs_WT_F09.04906.04906.2 5.47E-08 22-Oct R.TSNEVTVETDK[136.11]K[136.11].T "sp|Q9NRY5|F1142_HUMAN,tr|E7ESJ7|E7ESJ7_HUMAN" 2 1365.6958 1.28 126551 4906 2 1365.694636 683.8552 Protein FAM114A2 OS=Homo sapiens OX=9606 GN=FAM114A2 PE=1 SV=4 4.68 1475.8 - 146139 - - - -0.8809 - 2.108 0.616 - 351.7 1 2 0 -0.0012 12 0 0 0 3.08E+06 2.42E+06 - - - 5.5526 0.9999 221125_WJC_METTL3_EV_vs_WT_F09.04907.04907.2 5.48E-07 22-Dec R.TSNEVTVETDKK.T "sp|Q9NRY5|F1142_HUMAN,tr|E7ESJ7|E7ESJ7_HUMAN" 2 1349.6674 1.28 126552 4907 2 1349.666013 675.841 Protein FAM114A2 OS=Homo sapiens OX=9606 GN=FAM114A2 PE=1 SV=4 4.68 1475.9 - 140028 - - - -1.0566 - 2.464 0.558 - 587.5 1 2 0 -0.0014 12 0 0 0 3.08E+06 2.42E+06 - - - 5.5347 0.9277 221125_WJC_METTL3_EV_vs_WT_F09.04910.04910.2 0.0312 14-Nov K.LRDDFEKK.M "sp|Q9Y2W1|TR150_HUMAN,tr|A0A3B3ITZ9|A0A3B3ITZ9_HUMAN" 2 1049.5506 2.82 126553 4910 2 1049.549028 525.7826 Thyroid hormone receptor-associated protein 3 OS=Homo sapiens OX=9606 GN=THRAP3 PE=1 SV=2 6.12 1476.3 - 1.73E+06 - - - -1.4587 - 1.743 0.061 - 433.3 1 2 1 -0.0015 8 0 0 0 1.15E+08 4.08E+07 - - - 1.1668 0.9912 221125_WJC_METTL3_EV_vs_WT_F09.04913.04913.2 0.0156 14-Sep K.LR[166.11]DDFEK[136.11]K[136.11].M "sp|Q9Y2W1|TR150_HUMAN,tr|A0A3B3ITZ9|A0A3B3ITZ9_HUMAN" 2 1075.5872 2.82 126556 4913 2 1075.58539 538.8009 Thyroid hormone receptor-associated protein 3 OS=Homo sapiens OX=9606 GN=THRAP3 PE=1 SV=2 6.12 1476.6 - 1.09E+06 - - - -1.7098 - 1.843 0.305 - 285.2 1 2 1 -0.0018 8 0 0 0 1.15E+08 4.08E+07 - - - 3.1371 0.9985 221125_WJC_METTL3_EV_vs_WT_F09.04914.04914.3 0.0147 Aug-40 R.YLDEADR[166.11]DK[136.11]ER[166.11].Y "sp|Q9NP66|HM20A_HUMAN,tr|H0YKM5|H0YKM5_HUMAN" 2 1436.689 2.92 126557 4914 3 1436.686858 479.9036 High mobility group protein 20A OS=Homo sapiens OX=9606 GN=HMG20A PE=1 SV=1 4.44 1476.7 - 681305 - - - -1.4993 - 1.436 0.43 - 64.1 1 2 2 -0.0022 11 0 0 0 1.83E+07 6.29E+06 - - - 4.3615 0.9985 221125_WJC_METTL3_EV_vs_WT_F09.04916.04916.3 0.000204 14/40 K.NAELEK[136.11]DAQNR[166.11].L sp|Q2TAL8|QRIC1_HUMAN 1 1304.644 1.57 126559 4916 3 1304.638667 435.8886 Transcriptional regulator QRICH1 OS=Homo sapiens OX=9606 GN=QRICH1 PE=1 SV=1 4.68 1477 - 583884 - - - -4.0586 - 2.767 0.426 - 306.1 1 2 1 -0.0053 11 0 0 0 1.15E+07 7.34E+06 - - - 6.1793 1 221125_WJC_METTL3_EV_vs_WT_F09.04917.04917.2 3.00E-07 24-Nov K.DGGPVTSQESGQK[136.11].L "sp|Q9BXW9|FACD2_HUMAN,tr|A0A6Q8PFY3|A0A6Q8PFY3_HUMAN,tr|H7BZJ7|H7BZJ7_HUMAN" 3 1296.6037 0.4 126560 4917 2 1296.603144 649.3091 Fanconi anemia group D2 protein OS=Homo sapiens OX=9606 GN=FANCD2 PE=1 SV=2 4.37 1477.1 - 337060 - - - -0.4466 - 2.302 0.646 - 371.7 1 2 0 -0.0006 13 0 0 0 1.43E+06 3.57E+06 - - - 5.9521 0.9987 221125_WJC_METTL3_EV_vs_WT_F09.04918.04918.2 1.25 18-Nov R.HIDQQIQGSR.L "sp|Q14999|CUL7_HUMAN,tr|A0A669KB95|A0A669KB95_HUMAN,tr|A0A669KAU7|A0A669KAU7_HUMAN,tr|A0A669KBH4|A0A669KBH4_HUMAN" 4 1180.5949 0.66 126561 4918 2 1180.591495 591.3047 Cullin-7 OS=Homo sapiens OX=9606 GN=CUL7 PE=1 SV=2 6.74 1477.2 - 336641 - - - -2.8706 - 2.09 0.32 - 361.2 1 2 0 -0.0034 10 0 0 0 3.27E+06 4.97E+06 - - - 3.4611 0.7839 221125_WJC_METTL3_EV_vs_WT_F09.04919.04919.2 0.194 20-Apr R.NPSVIDKQDKD.- "sp|Q9NPL8|TIDC1_HUMAN,tr|C9JU35|C9JU35_HUMAN" 2 1257.6201 0.14 126562 4919 2 1257.620689 629.8173 "Complex I assembly factor TIMMDC1, mitochondrial OS=Homo sapiens OX=9606 GN=TIMMDC1 PE=1 SV=2" 4.68 1477.4 - 177202 - - - 0.4723 - 1.141 0.176 - 15.4 23 2 1 0.0006 11 0 0 0 1.80E+06 1.26E+07 - - - 0.0893 0.9998 221125_WJC_METTL3_EV_vs_WT_F09.04925.04925.2 0.00243 14/18 R.RVEEDIQQQK.A sp|P15924|DESP_HUMAN 1 1271.647 25.11 126566 4925 2 1271.646738 636.8308 Desmoplakin OS=Homo sapiens OX=9606 GN=DSP PE=1 SV=3 4.68 1478.1 - 2.10E+06 - - - -0.1895 - 2.489 0.378 - 739.6 1 2 0 -0.0002 10 0 0 0 6.41E+07 2.55E+06 - - - 4.3782 0.9993 221125_WJC_METTL3_EV_vs_WT_F09.04927.04927.3 0.00211 13/40 K.NAELEKDAQNR.L sp|Q2TAL8|QRIC1_HUMAN 1 1286.6215 1.58 126568 4927 3 1286.619355 429.8811 Transcriptional regulator QRICH1 OS=Homo sapiens OX=9606 GN=QRICH1 PE=1 SV=1 4.68 1478.2 - 1.30E+06 - - - -1.6609 - 2.206 0.388 - 367.7 1 2 1 -0.0021 11 0 0 0 1.16E+07 7.34E+06 - - - 5.1128 1 221125_WJC_METTL3_EV_vs_WT_F09.04930.04930.2 3.85E-07 14/30 K.TGGTVESDGSTESTGR.L sp|Q8NDV7|TNR6A_HUMAN 1 1539.6649 4.27 126571 4930 2 1539.665379 770.8397 Trinucleotide repeat-containing gene 6A protein OS=Homo sapiens OX=9606 GN=TNRC6A PE=1 SV=2 4.14 1478.6 - 214506 - - - 0.3286 - 2.739 0.69 - 583.6 1 2 0 0.0005 16 0 0 0 5.30E+06 1.24E+06 - - - 6.6144 0.9991 221125_WJC_METTL3_EV_vs_WT_F09.04931.04931.2 0.00176 20-Jul K.QVHPDTGISSK.A "sp|Q8N257|H2B3B_HUMAN,sp|P33778|H2B1B_HUMAN,sp|Q96A08|H2B1A_HUMAN,sp|Q5QNW6|H2B2F_HUMAN,sp|P58876|H2B1D_HUMAN,sp|Q99880|H2B1L_HUMAN,sp|P62807|H2B1C_HUMAN,sp|Q99877|H2B1N_HUMAN,sp|P57053|H2BFS_HUMAN,sp|P23527|H2B1O_HUMAN,sp|O60814|H2B1K_HUMAN,sp|Q93079|H2B1H_HUMAN,sp|Q99879|H2B1M_HUMAN,sp|Q16778|H2B2E_HUMAN,sp|P06899|H2B1J_HUMAN,tr|U3KQK0|U3KQK0_HUMAN" 16 1167.5884 0.99 126572 4931 2 1167.587016 584.8015 Histone H2B type 3-B OS=Homo sapiens OX=9606 GN=H2BU1 PE=1 SV=3 6.74 1478.7 - 96067.9 - - - -1.1862 - 1.33 0.389 - 115.3 1 2 0 -0.0014 11 0 0 0 2.08E+07 2.11E+07 - - - 2.6852 0.9997 221125_WJC_METTL3_EV_vs_WT_F09.04933.04933.2 0.31 18-Nov R.HIDQQIQGSR[166.11].L "sp|Q14999|CUL7_HUMAN,tr|A0A669KB95|A0A669KB95_HUMAN,tr|A0A669KAU7|A0A669KAU7_HUMAN,tr|A0A669KBH4|A0A669KBH4_HUMAN" 4 1190.6032 0.66 126573 4933 2 1190.602242 596.3089 Cullin-7 OS=Homo sapiens OX=9606 GN=CUL7 PE=1 SV=2 6.74 1478.9 - 356023 - - - -0.766 - 2.017 0.357 - 323.6 1 2 0 -0.0009 10 0 0 0 3.27E+06 4.97E+06 - - - 3.6359 0.9994 221125_WJC_METTL3_EV_vs_WT_F09.04935.04935.3 0.000622 14/36 R.LRSEIDNVKK.Q sp|P04264|K2C1_HUMAN 1 1200.6826 61819.55 126574 4935 3 1200.681725 401.2348 "Keratin, type II cytoskeletal 1 OS=Homo sapiens OX=9606 GN=KRT1 PE=1 SV=6" 8.59 1479.1 - 1.55E+07 - - - -0.7587 - 2.568 0.329 - 298.6 1 2 1 -0.0009 10 0 0 0 1.71E+10 2.77E+05 - - - 4.9621 0.9996 221125_WJC_METTL3_EV_vs_WT_F09.04939.04939.3 0.000787 Nov-40 K.QVHPDTGISSK[136.11].A "sp|Q8N257|H2B3B_HUMAN,sp|P33778|H2B1B_HUMAN,sp|Q96A08|H2B1A_HUMAN,sp|Q5QNW6|H2B2F_HUMAN,sp|P58876|H2B1D_HUMAN,sp|Q99880|H2B1L_HUMAN,sp|P62807|H2B1C_HUMAN,sp|Q99877|H2B1N_HUMAN,sp|P57053|H2BFS_HUMAN,sp|P23527|H2B1O_HUMAN,sp|O60814|H2B1K_HUMAN,sp|Q93079|H2B1H_HUMAN,sp|Q99879|H2B1M_HUMAN,sp|Q16778|H2B2E_HUMAN,sp|P06899|H2B1J_HUMAN,tr|U3KQK0|U3KQK0_HUMAN" 16 1175.6026 1.79 126578 4939 3 1175.59991 392.8748 Histone H2B type 3-B OS=Homo sapiens OX=9606 GN=H2BU1 PE=1 SV=3 6.74 1479.3 - 2.01E+06 - - - -2.289 - 2.046 0.373 - 166.4 1 2 0 -0.0027 11 0 0 0 2.12E+08 1.19E+08 - - - 4.7315 0.9957 221125_WJC_METTL3_EV_vs_WT_F09.04943.04943.2 0.00775 18-Dec R.LRSEIDNVKK.Q sp|P04264|K2C1_HUMAN 1 1200.6826 999 126582 4943 2 1200.681421 601.3486 "Keratin, type II cytoskeletal 1 OS=Homo sapiens OX=9606 GN=KRT1 PE=1 SV=6" 8.59 1479.7 - 887722 - - - -1.0119 - 2.195 0.308 - 369.5 1 2 1 -0.0012 10 0 0 0 1.57E+09 0.00E+00 - - - 3.51 1 221125_WJC_METTL3_EV_vs_WT_F09.04946.04946.3 3.21E-05 14/44 R.YAAVHVHTNAAR.Q "sp|P49593|PPM1F_HUMAN,tr|C9J2F3|C9J2F3_HUMAN,tr|B5MCT7|B5MCT7_HUMAN,tr|A8MX49|A8MX49_HUMAN" 4 1308.6687 1.18 126585 4946 3 1308.667555 437.2302 Protein phosphatase 1F OS=Homo sapiens OX=9606 GN=PPM1F PE=1 SV=3 8.76 1479.9 - 385838 - - - -0.8879 - 2.219 0.508 - 186.8 1 2 0 -0.0012 12 0 0 0 1.45E+07 1.22E+07 - - - 6.4127 0.9999 221125_WJC_METTL3_EV_vs_WT_F09.04947.04947.2 9.31E-05 13/22 R.K[136.11]PAQQSLGSQVK[136.11].T sp|Q99626|CDX2_HUMAN 1 1285.7325 2.52 126586 4947 2 1285.730376 643.8735 Homeobox protein CDX-2 OS=Homo sapiens OX=9606 GN=CDX2 PE=1 SV=3 10 1480.1 - 328699 - - - -1.652 - 2.854 0.51 - 475.8 1 2 0 -0.0021 12 0 0 0 8.18E+06 3.24E+06 - - - 5.5666 0.9999 221125_WJC_METTL3_EV_vs_WT_F09.04949.04949.2 3.54E-05 20-Nov K.QVHPDTGISSK[136.11].A "sp|Q8N257|H2B3B_HUMAN,sp|P33778|H2B1B_HUMAN,sp|Q96A08|H2B1A_HUMAN,sp|Q5QNW6|H2B2F_HUMAN,sp|P58876|H2B1D_HUMAN,sp|Q99880|H2B1L_HUMAN,sp|P62807|H2B1C_HUMAN,sp|Q99877|H2B1N_HUMAN,sp|P57053|H2BFS_HUMAN,sp|P23527|H2B1O_HUMAN,sp|O60814|H2B1K_HUMAN,sp|Q93079|H2B1H_HUMAN,sp|Q99879|H2B1M_HUMAN,sp|Q16778|H2B2E_HUMAN,sp|P06899|H2B1J_HUMAN,tr|U3KQK0|U3KQK0_HUMAN" 16 1175.6026 0.99 126588 4949 2 1175.601411 588.8086 Histone H2B type 3-B OS=Homo sapiens OX=9606 GN=H2BU1 PE=1 SV=3 6.74 1480.3 - 268534 - - - -1.0122 - 2.179 0.539 - 376.3 1 2 0 -0.0012 11 0 0 0 2.08E+07 2.11E+07 - - - 5.1287 0.9996 221125_WJC_METTL3_EV_vs_WT_F09.04958.04958.3 1.66E-05 Nov-40 K.SNNHENVSLAK.A "sp|Q96MU7|YTDC1_HUMAN,tr|J3QR07|J3QR07_HUMAN" 2 1211.5895 1.44 126595 4958 3 1211.584489 404.8704 YTH domain-containing protein 1 OS=Homo sapiens OX=9606 GN=YTHDC1 PE=1 SV=3 6.47 1481.3 - 2.57E+06 - - - -4.1062 - 2.188 0.462 - 156.7 1 2 0 -0.005 11 0 0 0 6.47E+07 4.49E+07 - - - 5.9138 0.9996 221125_WJC_METTL3_EV_vs_WT_F09.04959.04959.3 0.000137 Oct-40 K.SNNHENVSLAK[136.11].A "sp|Q96MU7|YTDC1_HUMAN,tr|J3QR07|J3QR07_HUMAN" 2 1219.6037 1.44 126596 4959 3 1219.598902 407.5418 YTH domain-containing protein 1 OS=Homo sapiens OX=9606 GN=YTHDC1 PE=1 SV=3 6.47 1481.3 - 2.30E+06 - - - -3.9045 - 1.996 0.487 - 139.6 1 2 0 -0.0048 11 0 0 0 6.48E+07 4.49E+07 - - - 5.9317 0.9995 221125_WJC_METTL3_EV_vs_WT_F09.04964.04964.2 0.000841 20-Dec K.SNNHENVSLAK.A "sp|Q96MU7|YTDC1_HUMAN,tr|J3QR07|J3QR07_HUMAN" 2 1211.5895 1.46 126601 4964 2 1211.585926 606.802 YTH domain-containing protein 1 OS=Homo sapiens OX=9606 GN=YTHDC1 PE=1 SV=3 6.47 1481.9 - 400610 - - - -2.9201 - 2.206 0.513 - 367 1 2 0 -0.0035 11 0 0 0 7.80E+06 5.35E+06 - - - 4.9692 0.9943 221125_WJC_METTL3_EV_vs_WT_F09.04967.04967.2 0.228 14-Aug R.SEIDNVKK.Q sp|P04264|K2C1_HUMAN 1 931.4975 58.75 126602 4967 2 931.494657 466.756 "Keratin, type II cytoskeletal 1 OS=Homo sapiens OX=9606 GN=KRT1 PE=1 SV=6" 5.79 1482.3 - 1.09E+07 - - - -3.0102 - 1.526 0.251 - 298 1 2 0 -0.0028 8 0 0 0 1.14E+08 1.94E+06 - - - 2.1687 1 221125_WJC_METTL3_EV_vs_WT_F09.04973.04973.2 0.000298 13/20 K.SNNHENVSLAK[136.11].A "sp|Q96MU7|YTDC1_HUMAN,tr|J3QR07|J3QR07_HUMAN" 2 1219.6037 1.46 126608 4973 2 1219.600125 610.8091 YTH domain-containing protein 1 OS=Homo sapiens OX=9606 GN=YTHDC1 PE=1 SV=3 6.47 1482.7 - 849069 - - - -2.9018 - 2.66 0.569 - 690.6 1 2 0 -0.0035 11 0 0 0 7.80E+06 5.35E+06 - - - 5.8891 0.9996 221125_WJC_METTL3_EV_vs_WT_F09.04974.04974.2 0.00351 22-Dec R.ESQVVSENGQEK[136.11].V sp|Q9P2D1|CHD7_HUMAN 1 1340.6299 1.44 126609 4974 2 1340.627513 671.3222 Chromodomain-helicase-DNA-binding protein 7 OS=Homo sapiens OX=9606 GN=CHD7 PE=1 SV=3 4.25 1482.9 - 580311 - - - -1.8089 - 2.177 0.404 - 542 1 2 0 -0.0024 12 0 0 0 7.80E+06 5.43E+06 - - - 4.0711 0.8311 221125_WJC_METTL3_EV_vs_WT_F09.04983.04983.2 0.0223 16-Sep L.RSEIDNVKK.Q sp|P04264|K2C1_HUMAN 1 1087.5986 999 126614 4983 2 1087.594633 544.8066 "Keratin, type II cytoskeletal 1 OS=Homo sapiens OX=9606 GN=KRT1 PE=1 SV=6" 8.59 1484 - 1.13E+06 - - - -3.6217 - 1.88 0.298 - 229.3 1 1 0 -0.0039 9 0 0 0 1.50E+07 0.00E+00 - - - 3.0671 0.9831 221125_WJC_METTL3_EV_vs_WT_F09.04984.04984.2 0.0138 16-Nov R.LRSEIDNVK.K sp|P04264|K2C1_HUMAN 1 1072.5877 999 126615 4984 2 1072.584997 537.3011 "Keratin, type II cytoskeletal 1 OS=Homo sapiens OX=9606 GN=KRT1 PE=1 SV=6" 6.07 1484.1 - 1.59E+06 - - - -2.4949 - 2.123 0.245 - 447.5 1 2 1 -0.0027 9 0 0 0 1.74E+07 0.00E+00 - - - 3.0277 1 221125_WJC_METTL3_EV_vs_WT_F09.04985.04985.2 1.58E-07 14/26 R.AQAVSEDAGGNEGR.A "sp|P55884|EIF3B_HUMAN,tr|C9JZG1|C9JZG1_HUMAN" 2 1359.6015 1.28 126616 4985 2 1359.600002 680.808 Eukaryotic translation initiation factor 3 subunit B OS=Homo sapiens OX=9606 GN=EIF3B PE=1 SV=3 4.14 1484.2 - 1.24E+06 - - - -1.0908 - 2.472 0.668 - 599 1 2 0 -0.0015 14 0 0 0 2.02E+07 1.57E+07 - - - 6.2455 0.9979 221125_WJC_METTL3_EV_vs_WT_F09.04986.04986.2 0.0366 16-Dec K.YK[136.11]AEDEVQR[166.11].E "sp|P0DMV8|HS71A_HUMAN,sp|P34931|HS71L_HUMAN,sp|P0DMV9|HS71B_HUMAN,tr|Q53FA3|Q53FA3_HUMAN,tr|V9GZ37|V9GZ37_HUMAN,tr|A0A0G2JIW1|A0A0G2JIW1_HUMAN" 6 1154.5687 0.12 126617 4986 2 1154.567585 578.2916 Heat shock 70 kDa protein 1A OS=Homo sapiens OX=9606 GN=HSPA1A PE=1 SV=1 4.68 1484.3 - 1.01E+06 - - - -0.9415 - 2.105 0.429 - 394.7 1 2 1 -0.0011 9 0 0 0 1.21E+07 9.77E+07 - - - 4.3626 0.9993 221125_WJC_METTL3_EV_vs_WT_F09.04989.04989.3 3.46E-05 13/32 K.YK[136.11]AEDEVQR[166.11].E "sp|P0DMV8|HS71A_HUMAN,sp|P34931|HS71L_HUMAN,sp|P0DMV9|HS71B_HUMAN,tr|Q53FA3|Q53FA3_HUMAN,tr|V9GZ37|V9GZ37_HUMAN,tr|A0A0G2JIW1|A0A0G2JIW1_HUMAN" 6 1154.5687 0.01 126618 4989 3 1154.565733 385.8635 Heat shock 70 kDa protein 1A OS=Homo sapiens OX=9606 GN=HSPA1A PE=1 SV=1 4.68 1484.7 - 1.69E+07 - - - -2.5455 - 2.502 0.405 - 306.5 1 2 1 -0.0029 9 0 0 0 3.13E+06 3.79E+08 - - - 5.8185 0.9992 221125_WJC_METTL3_EV_vs_WT_F09.04990.04990.2 0.00165 20-Nov K.VSVQNGSIHQK.D "sp|Q7Z739|YTHD3_HUMAN,tr|S4R373|S4R373_HUMAN" 2 1195.6309 1.47 126619 4990 2 1195.627422 598.8227 YTH domain-containing family protein 3 OS=Homo sapiens OX=9606 GN=YTHDF3 PE=1 SV=1 8.73 1484.8 - 4.46E+06 - - - -2.9382 - 1.921 0.445 - 201.6 1 2 0 -0.0035 11 0 0 0 3.33E+07 2.26E+07 - - - 4.0928 0.9999 221125_WJC_METTL3_EV_vs_WT_F09.04991.04991.3 2.16E-05 Dec-44 R.ANVVTTPSTNRK.N "sp|Q8IWZ3|ANKH1_HUMAN,tr|E9PDP5|E9PDP5_HUMAN,tr|H0Y472|H0Y472_HUMAN,tr|H0Y4P6|H0Y4P6_HUMAN,tr|H0Y785|H0Y785_HUMAN" 5 1286.6943 1.15 126620 4991 3 1286.691838 429.9054 Ankyrin repeat and KH domain-containing protein 1 OS=Homo sapiens OX=9606 GN=ANKHD1 PE=1 SV=1 11 1484.8 - 4.98E+06 - - - -1.8847 - 2.57 0.451 - 271.5 1 2 0 -0.0024 12 0 0 0 1.31E+08 1.14E+08 - - - 6.1839 0.9998 221125_WJC_METTL3_EV_vs_WT_F09.04992.04992.3 3.81E-05 13/44 R.NTAELQPESGK[136.11]R[166.11].K sp|O15355|PPM1G_HUMAN 1 1346.6909 0.69 126621 4992 3 1346.687274 449.9042 Protein phosphatase 1G OS=Homo sapiens OX=9606 GN=PPM1G PE=1 SV=1 6.14 1484.9 - 4.14E+06 - - - -2.7014 - 2.348 0.412 - 184.1 1 2 0 -0.0036 12 0 0 0 2.53E+07 3.65E+07 - - - 5.4983 0.9992 221125_WJC_METTL3_EV_vs_WT_F09.04995.04995.3 8.80E-05 13/48 K.ISTTTSEEPC[160.03]R[166.11]DK[136.11].G sp|O15119|TBX3_HUMAN 1 1540.7158 1 126624 4995 3 1540.711082 514.5792 T-box transcription factor TBX3 OS=Homo sapiens OX=9606 GN=TBX3 PE=1 SV=4 4.68 1485.1 - 1.08E+06 - - - -3.0668 - 2.108 0.491 - 187.2 1 2 1 -0.0047 13 0 0 0 5.57E+06 5.58E+06 - - - 6.0348 1 221125_WJC_METTL3_EV_vs_WT_F09.04999.04999.3 8.63E-06 15/40 R.SPHHALGLSSR[166.11].Y sp|Q96F45|ZN503_HUMAN 1 1170.6133 1.22 126626 4999 3 1170.611548 391.2117 Zinc finger protein 503 OS=Homo sapiens OX=9606 GN=ZNF503 PE=1 SV=1 9.51 1485.7 - 6.88E+06 - - - -1.5172 - 3.234 0.497 - 328 1 2 0 -0.0018 11 0 0 0 1.29E+08 1.06E+08 - - - 7.4149 0.9994 221125_WJC_METTL3_EV_vs_WT_F09.05000.05000.3 0.491 Dec-44 R.ANVVTTPSTNR[166.11]K[136.11].N "sp|Q8IWZ3|ANKH1_HUMAN,tr|E9PDP5|E9PDP5_HUMAN,tr|H0Y472|H0Y472_HUMAN,tr|H0Y4P6|H0Y4P6_HUMAN,tr|H0Y785|H0Y785_HUMAN" 5 1304.7167 1.14 126627 5000 3 1304.715184 435.9129 Ankyrin repeat and KH domain-containing protein 1 OS=Homo sapiens OX=9606 GN=ANKHD1 PE=1 SV=1 11 1485.7 - 5.47E+06 - - - -1.1872 - 2.503 0.242 - 210.4 1 2 0 -0.0015 12 0 0 0 1.32E+08 1.15E+08 - - - 3.7808 0.9985 221125_WJC_METTL3_EV_vs_WT_F09.05002.05002.3 0.0101 Nov-44 R.NTAELQPESGKR.K sp|O15355|PPM1G_HUMAN 1 1328.6684 0.69 126629 5002 3 1328.666957 443.8968 Protein phosphatase 1G OS=Homo sapiens OX=9606 GN=PPM1G PE=1 SV=1 6.14 1485.8 - 2.98E+06 - - - -1.1177 - 2.209 0.21 - 169.5 1 2 0 -0.0015 12 0 0 0 2.51E+07 3.65E+07 - - - 3.0777 0.994 221125_WJC_METTL3_EV_vs_WT_F09.05003.05003.3 3.17E-05 15/32 K.YKAEDEVQR.E "sp|P0DMV8|HS71A_HUMAN,sp|P34931|HS71L_HUMAN,sp|P0DMV9|HS71B_HUMAN,tr|Q53FA3|Q53FA3_HUMAN,tr|V9GZ37|V9GZ37_HUMAN,tr|A0A0G2JIW1|A0A0G2JIW1_HUMAN" 6 1136.5462 0.01 126630 5003 3 1137.547359 379.856 Heat shock 70 kDa protein 1A OS=Homo sapiens OX=9606 GN=HSPA1A PE=1 SV=1 4.68 1485.8 - 1.87E+06 - - - 880.8766 - 2.763 0.481 - 384.5 1 2 1 1.0012 9 0 0 0 3.13E+06 3.79E+08 - - - 6.6883 1 221125_WJC_METTL3_EV_vs_WT_F09.05004.05004.2 2.31E-06 14/22 R.NSPGSQVASNPR[166.11].Q sp|Q9H0D6|XRN2_HUMAN 1 1222.593 1.4 126631 5004 2 1222.591524 612.3038 5'-3' exoribonuclease 2 OS=Homo sapiens OX=9606 GN=XRN2 PE=1 SV=1 9.75 1485.9 - 1.66E+06 - - - -1.1934 - 2.5 0.61 - 796.5 1 2 0 -0.0015 12 0 0 0 2.44E+07 1.74E+07 - - - 5.9569 0.9688 221125_WJC_METTL3_EV_vs_WT_F09.05007.05007.2 0.0052 18-Sep V.SVQNGSIHQK[136.11].D "sp|Q7Z739|YTHD3_HUMAN,tr|A0A087WY31|A0A087WY31_HUMAN,tr|S4R373|S4R373_HUMAN,tr|A0A087X0U5|A0A087X0U5_HUMAN,tr|A0A087WU40|A0A087WU40_HUMAN" 5 1104.5767 1.18 126634 5007 2 1104.575755 553.2956 YTH domain-containing family protein 3 OS=Homo sapiens OX=9606 GN=YTHDF3 PE=1 SV=1 8.49 1486.3 - 1.05E+06 - - - -0.8745 - 1.549 0.382 - 206.9 1 1 0 -0.001 10 0 0 0 7.17E+06 6.08E+06 - - - 3.0837 0.9997 221125_WJC_METTL3_EV_vs_WT_F09.05008.05008.2 0.00424 22-Oct R.ANVVTTPSTNRK.N "sp|Q8IWZ3|ANKH1_HUMAN,tr|E9PDP5|E9PDP5_HUMAN,tr|H0Y472|H0Y472_HUMAN,tr|H0Y4P6|H0Y4P6_HUMAN,tr|H0Y785|H0Y785_HUMAN" 5 1286.6943 1.18 126635 5008 2 1286.692935 644.3544 Ankyrin repeat and KH domain-containing protein 1 OS=Homo sapiens OX=9606 GN=ANKHD1 PE=1 SV=1 11 1486.4 - 559541 - - - -1.0321 - 2.097 0.391 - 353 1 2 0 -0.0013 12 0 0 0 1.03E+07 8.74E+06 - - - 3.8769 0.9947 221125_WJC_METTL3_EV_vs_WT_F09.05009.05009.2 0.0158 22-Sep R.ANVVTTPSTNR[166.11]K[136.11].N "sp|Q8IWZ3|ANKH1_HUMAN,tr|E9PDP5|E9PDP5_HUMAN,tr|H0Y472|H0Y472_HUMAN,tr|H0Y4P6|H0Y4P6_HUMAN,tr|H0Y785|H0Y785_HUMAN" 5 1304.7167 1.18 126636 5009 2 1304.710733 653.3656 Ankyrin repeat and KH domain-containing protein 1 OS=Homo sapiens OX=9606 GN=ANKHD1 PE=1 SV=1 11 1486.5 - 501872 - - - -4.5987 - 1.758 0.382 - 285.7 1 2 0 -0.006 12 0 0 0 1.03E+07 8.74E+06 - - - 3.345 0.9386 221125_WJC_METTL3_EV_vs_WT_F09.05010.05010.2 2.33E-06 18-Nov R.KIEVNNATAR.V "sp|O43251|RFOX2_HUMAN,sp|Q9NWB1|RFOX1_HUMAN,sp|A6NFN3|RFOX3_HUMAN,tr|A0A6Q8PGE0|A0A6Q8PGE0_HUMAN,tr|A0A6Q8PH77|A0A6Q8PH77_HUMAN,tr|A0A286YEU2|A0A286YEU2_HUMAN,tr|A0A087X2B1|A0A087X2B1_HUMAN,tr|F8VR27|F8VR27_HUMAN,tr|B7Z1U7|B7Z1U7_HUMAN,tr|B0QYV1|B0QYV1_HUMAN,tr|A0A6Q8PHA3|A0A6Q8PHA3_HUMAN,tr|A0A3B3ITL7|A0A3B3ITL7_HUMAN,tr|F8VZY7|F8VZY7_HUMAN,tr|B0QYY4|B0QYY4_HUMAN,tr|J3KNW3|J3KNW3_HUMAN,tr|F8VZG9|F8VZG9_HUMAN,tr|J3QRF4|J3QRF4_HUMAN,tr|F8VRS4|F8VRS4_HUMAN,tr|A0A6Q8PFM4|A0A6Q8PFM4_HUMAN,tr|S4R469|S4R469_HUMAN,tr|A0A804HKG7|A0A804HKG7_HUMAN,tr|A0A0G2JRD1|A0A0G2JRD1_HUMAN,tr|A0A0G2JRA5|A0A0G2JRA5_HUMAN,tr|A0A804HJM2|A0A804HJM2_HUMAN,tr|I3L1D4|I3L1D4_HUMAN,tr|S4R3K7|S4R3K7_HUMAN" 26 1114.6095 1.23 126637 5010 2 1114.599482 558.312 RNA binding protein fox-1 homolog 2 OS=Homo sapiens OX=9606 GN=RBFOX2 PE=1 SV=3 8.75 1486.7 - 496624 - - - -8.9619 - 2.303 0.255 - 430.7 1 2 0 -0.01 10 0 0 0 1.36E+07 1.11E+07 - - - 3.2498 1 221125_WJC_METTL3_EV_vs_WT_F09.05014.05014.3 1.04E-07 18/40 R.SPHHALGLSSR.Y sp|Q96F45|ZN503_HUMAN 1 1160.6051 1.22 126639 5014 3 1160.603189 387.8756 Zinc finger protein 503 OS=Homo sapiens OX=9606 GN=ZNF503 PE=1 SV=1 9.51 1487.2 - 3.01E+07 - - - -1.6069 - 3.601 0.513 - 547.8 1 2 0 -0.0019 11 0 0 0 1.29E+08 1.06E+08 - - - 7.8986 0.9998 221125_WJC_METTL3_EV_vs_WT_F09.05015.05015.3 5.40E-05 Nov-44 R.K[136.11]LQETQMSTTSK[136.11].L "sp|Q13948|CASP_HUMAN,sp|P39880|CUX1_HUMAN,tr|A0A2R8Y8D0|A0A2R8Y8D0_HUMAN,tr|A0A2R8Y852|A0A2R8Y852_HUMAN,tr|A0A2R8YDI1|A0A2R8YDI1_HUMAN" 5 1396.7203 1.01 126640 5015 3 1396.717749 466.5807 Protein CASP OS=Homo sapiens OX=9606 GN=CUX1 PE=1 SV=2 8.59 1487.2 - 4.93E+06 - - - -1.8121 - 2.135 0.408 - 243.9 1 2 0 -0.0025 12 0 0 0 2.24E+07 2.22E+07 - - - 5.1905 0.9939 221125_WJC_METTL3_EV_vs_WT_F09.05018.05018.2 0.000281 14/18 L.ASDSHRPEVK.L "sp|Q9NYF8|BCLF1_HUMAN,tr|E9PKI6|E9PKI6_HUMAN,tr|A0A1W2PQ43|A0A1W2PQ43_HUMAN,tr|E9PK91|E9PK91_HUMAN,tr|E9PJA7|E9PJA7_HUMAN,tr|E9PK09|E9PK09_HUMAN,tr|E9PQN2|E9PQN2_HUMAN" 7 1124.5574 3 126643 5018 2 1124.556633 563.286 Bcl-2-associated transcription factor 1 OS=Homo sapiens OX=9606 GN=BCLAF1 PE=1 SV=2 6.8 1487.4 - 3.06E+06 - - - -0.7132 - 2.554 0.501 - 798.3 1 1 0 -0.0008 10 0 0 0 4.13E+07 1.38E+07 - - - 5.3584 1 221125_WJC_METTL3_EV_vs_WT_F09.05020.05020.3 7.13E-07 15/44 R.VDC[160.03]DQHSDIAQR[166.11].Y sp|Q9BS26|ERP44_HUMAN 1 1452.6291 6.7 126645 5020 3 1452.626248 485.217 Endoplasmic reticulum resident protein 44 OS=Homo sapiens OX=9606 GN=ERP44 PE=1 SV=1 4.41 1487.5 - 1.45E+06 - - - -1.9709 - 2.927 0.506 - 483.9 1 2 0 -0.0029 12 0 0 0 5.20E+07 7.76E+06 - - - 7.1575 0.9997 221125_WJC_METTL3_EV_vs_WT_F09.05023.05023.2 6.68E-06 13/22 K.MIASDSHRPEVK.L "sp|Q9NYF8|BCLF1_HUMAN,tr|E9PKI6|E9PKI6_HUMAN,tr|A0A1W2PQ43|A0A1W2PQ43_HUMAN,tr|E9PK91|E9PK91_HUMAN,tr|E9PJA7|E9PJA7_HUMAN,tr|E9PK09|E9PK09_HUMAN,tr|E9PQN2|E9PQN2_HUMAN" 7 1368.682 2.05 126648 5023 2 1368.680498 685.3483 Bcl-2-associated transcription factor 1 OS=Homo sapiens OX=9606 GN=BCLAF1 PE=1 SV=2 6.51 1487.8 - 1.03E+06 - - - -1.0857 - 2.38 0.323 - 441.3 1 2 0 -0.0015 12 0 0 0 1.71E+07 8.34E+06 - - - 3.7077 0.9951 221125_WJC_METTL3_EV_vs_WT_F09.05024.05024.3 0.153 Sep-40 K.K[136.11]EPVSTNAVQR[166.11].R "sp|Q96CM3|RUSD4_HUMAN,tr|E9PJV3|E9PJV3_HUMAN" 2 1245.6796 1.61 126649 5024 3 1245.677976 416.2338 Mitochondrial RNA pseudouridine synthase RPUSD4 OS=Homo sapiens OX=9606 GN=RPUSD4 PE=1 SV=1 8.75 1487.8 - 1.03E+06 - - - -1.319 - 1.822 0.189 - 195 1 2 0 -0.0016 11 0 0 0 9.30E+06 5.77E+06 - - - 2.351 0.9934 221125_WJC_METTL3_EV_vs_WT_F09.05026.05026.2 2.14E-05 14/18 L.ASDSHR[166.11]PEVK[136.11].L "sp|Q9NYF8|BCLF1_HUMAN,tr|E9PKI6|E9PKI6_HUMAN,tr|A0A1W2PQ43|A0A1W2PQ43_HUMAN,tr|E9PK91|E9PK91_HUMAN,tr|E9PJA7|E9PJA7_HUMAN,tr|E9PK09|E9PK09_HUMAN,tr|E9PQN2|E9PQN2_HUMAN" 7 1142.5799 2.98 126651 5026 2 1142.578533 572.2972 Bcl-2-associated transcription factor 1 OS=Homo sapiens OX=9606 GN=BCLAF1 PE=1 SV=2 6.8 1488 - 1.02E+06 - - - -1.2008 - 2.57 0.536 - 755.5 1 1 0 -0.0014 10 0 0 0 4.10E+07 1.38E+07 - - - 5.6342 0.8602 221125_WJC_METTL3_EV_vs_WT_F09.05027.05027.3 0.0267 Nov-40 R.EKQPLEESASR.A "sp|Q9HC36|MRM3_HUMAN,tr|I3L0T6|I3L0T6_HUMAN" 2 1272.631 2.71 126652 5027 3 1272.625767 425.2176 "rRNA methyltransferase 3, mitochondrial OS=Homo sapiens OX=9606 GN=MRM3 PE=1 SV=2" 4.79 1488.1 - 833275 - - - -4.1072 - 1.829 0.188 - 210 1 2 1 -0.0052 11 0 0 0 1.98E+07 7.31E+06 - - - 2.3498 1 221125_WJC_METTL3_EV_vs_WT_F09.05028.05028.2 1.56E-08 19/22 R.KLQETQMSTTSK.L "sp|Q13948|CASP_HUMAN,sp|P39880|CUX1_HUMAN,tr|A0A2R8Y8D0|A0A2R8Y8D0_HUMAN,tr|A0A2R8Y852|A0A2R8Y852_HUMAN,tr|A0A2R8YDI1|A0A2R8YDI1_HUMAN" 5 1380.6919 0.81 126653 5028 2 1380.689678 691.3532 Protein CASP OS=Homo sapiens OX=9606 GN=CUX1 PE=1 SV=2 8.59 1488.3 - 770585 - - - -1.5949 - 3.394 0.565 - 1138.2 1 2 0 -0.0022 12 0 0 0 3.63E+06 4.47E+06 - - - 6.4287 0.9999 221125_WJC_METTL3_EV_vs_WT_F09.05030.05030.2 9.63E-06 14/22 K.MIASDSHR[166.11]PEVK[136.11].L "sp|Q9NYF8|BCLF1_HUMAN,tr|E9PKI6|E9PKI6_HUMAN,tr|A0A1W2PQ43|A0A1W2PQ43_HUMAN,tr|E9PK91|E9PK91_HUMAN,tr|E9PJA7|E9PJA7_HUMAN,tr|E9PK09|E9PK09_HUMAN,tr|E9PQN2|E9PQN2_HUMAN" 7 1386.7045 2.05 126655 5030 2 1386.702824 694.3595 Bcl-2-associated transcription factor 1 OS=Homo sapiens OX=9606 GN=BCLAF1 PE=1 SV=2 6.51 1488.5 - 630297 - - - -1.1754 - 2.433 0.576 - 425.1 1 2 0 -0.0016 12 0 0 0 1.71E+07 8.34E+06 - - - 5.6343 0.9997 221125_WJC_METTL3_EV_vs_WT_F09.05032.05032.2 0.00106 22-Oct R.NTAELQPESGK[136.11]R[166.11].K sp|O15355|PPM1G_HUMAN 1 1346.6909 0.71 126657 5032 2 1346.689501 674.3527 Protein phosphatase 1G OS=Homo sapiens OX=9606 GN=PPM1G PE=1 SV=1 6.14 1488.8 - 434689 - - - -1.0478 - 1.998 0.394 - 351.9 1 2 0 -0.0014 12 0 0 0 1.79E+06 2.52E+06 - - - 3.7718 0.9999 221125_WJC_METTL3_EV_vs_WT_F09.05036.05036.3 7.19E-05 Nov-36 K.DSDLSHVQNK.S "sp|O60506|HNRPQ_HUMAN,tr|A0A7I2YQV8|A0A7I2YQV8_HUMAN,tr|A0A7I2YQN2|A0A7I2YQN2_HUMAN,tr|A0A7I2V5Q6|A0A7I2V5Q6_HUMAN,tr|A0A7I2V4Z0|A0A7I2V4Z0_HUMAN,tr|A0A7I2V4J0|A0A7I2V4J0_HUMAN,tr|F6UXX1|F6UXX1_HUMAN,tr|A0A7I2V346|A0A7I2V346_HUMAN" 8 1141.5364 1.15 126659 5036 3 1141.535324 381.5194 Heterogeneous nuclear ribonucleoprotein Q OS=Homo sapiens OX=9606 GN=SYNCRIP PE=1 SV=2 5.21 1489.3 - 1.14E+07 - - - -0.9128 - 2.154 0.379 - 244.9 1 2 0 -0.001 10 0 0 0 9.45E+07 8.25E+07 - - - 5.0061 0.9961 221125_WJC_METTL3_EV_vs_WT_F09.05037.05037.3 0.0351 Jul-40 R.VYTDVNTHRPR.E "sp|P68400|CSK21_HUMAN,sp|Q8NEV1|CSK23_HUMAN,tr|A0A2R8YCK2|A0A2R8YCK2_HUMAN,tr|A0A2R8YFU2|A0A2R8YFU2_HUMAN,tr|V9GYA2|V9GYA2_HUMAN,tr|A0A2R8YEW1|A0A2R8YEW1_HUMAN,tr|A0A2R8Y4D6|A0A2R8Y4D6_HUMAN,tr|A0A2R8YD58|A0A2R8YD58_HUMAN,tr|A0A2R8YF43|A0A2R8YF43_HUMAN,tr|A0A2R8Y5A0|A0A2R8Y5A0_HUMAN,tr|A0A2R8YDY7|A0A2R8YDY7_HUMAN,tr|A0A2R8YF47|A0A2R8YF47_HUMAN,tr|A0A2R8Y4H0|A0A2R8Y4H0_HUMAN,tr|A0A2R8Y7T1|A0A2R8Y7T1_HUMAN,tr|A0A2R8YDP2|A0A2R8YDP2_HUMAN,tr|A0A2R8Y797|A0A2R8Y797_HUMAN,tr|A0A2R8YEL7|A0A2R8YEL7_HUMAN,tr|V9GY80|V9GY80_HUMAN,tr|A0A2R8YCC9|A0A2R8YCC9_HUMAN,tr|E7EU96|E7EU96_HUMAN,tr|A0A2R8Y3W6|A0A2R8Y3W6_HUMAN" 21 1356.6898 0.28 126660 5037 3 1356.689368 453.2372 Casein kinase II subunit alpha OS=Homo sapiens OX=9606 GN=CSNK2A1 PE=1 SV=1 8.72 1489.3 - 7.06E+06 - - - -0.3531 - 1.479 0.246 - 64.3 1 2 0 -0.0005 11 0 0 0 1.97E+07 6.98E+07 - - - 2.3943 0.9963 221125_WJC_METTL3_EV_vs_WT_F09.05039.05039.3 0.000242 Nov-40 M.IASDSHRPEVK.L "sp|Q9NYF8|BCLF1_HUMAN,tr|E9PKI6|E9PKI6_HUMAN,tr|A0A1W2PQ43|A0A1W2PQ43_HUMAN,tr|E9PK91|E9PK91_HUMAN,tr|E9PJA7|E9PJA7_HUMAN,tr|E9PK09|E9PK09_HUMAN,tr|E9PQN2|E9PQN2_HUMAN" 7 1237.6415 2.53 126662 5039 3 1237.639838 413.5544 Bcl-2-associated transcription factor 1 OS=Homo sapiens OX=9606 GN=BCLAF1 PE=1 SV=2 6.75 1489.4 - 5.59E+06 - - - -1.3421 - 2.457 0.485 - 114.3 1 1 0 -0.0017 11 0 0 0 2.48E+07 9.79E+06 - - - 6.5005 1 221125_WJC_METTL3_EV_vs_WT_F09.05040.05040.3 2.05E-06 18/60 K.APEGGEGAQPVPGHAR.K "sp|Q6W2J9|BCOR_HUMAN,tr|H7BZ37|H7BZ37_HUMAN,tr|H7C2V9|H7C2V9_HUMAN,tr|H7BYY2|H7BYY2_HUMAN,tr|H7C231|H7C231_HUMAN" 5 1528.7383 2.03 126663 5040 3 1528.737569 510.5867 BCL-6 corepressor OS=Homo sapiens OX=9606 GN=BCOR PE=1 SV=1 5.4 1489.5 - 4.67E+06 - - - -0.4474 - 2.862 0.559 - 297.2 1 2 0 -0.0007 16 0 0 0 1.01E+08 4.98E+07 - - - 7.4702 0.9521 221125_WJC_METTL3_EV_vs_WT_F09.05041.05041.2 0.361 16-Sep L.DDIVSGHK[136.11]K[136.11].K "sp|P49368|TCPG_HUMAN,tr|B4DUR8|B4DUR8_HUMAN" 2 1013.5477 0.2 126664 5041 2 1013.547075 507.7811 T-complex protein 1 subunit gamma OS=Homo sapiens OX=9606 GN=CCT3 PE=1 SV=4 6.75 1489.5 - 4.55E+06 - - - -0.5762 - 1.886 0.229 - 248.3 1 1 0 -0.0006 9 0 0 0 3.15E+06 1.56E+07 - - - 2.5677 0.9877 221125_WJC_METTL3_EV_vs_WT_F09.05044.05044.3 0.00089 13/40 M.IASDSHR[166.11]PEVK[136.11].L "sp|Q9NYF8|BCLF1_HUMAN,tr|E9PKI6|E9PKI6_HUMAN,tr|A0A1W2PQ43|A0A1W2PQ43_HUMAN,tr|E9PK91|E9PK91_HUMAN,tr|E9PJA7|E9PJA7_HUMAN,tr|E9PK09|E9PK09_HUMAN,tr|E9PQN2|E9PQN2_HUMAN" 7 1255.664 2.49 126667 5044 3 1255.66202 419.5619 Bcl-2-associated transcription factor 1 OS=Homo sapiens OX=9606 GN=BCLAF1 PE=1 SV=2 6.75 1489.6 - 2.96E+06 - - - -1.5522 - 2.665 0.358 - 374.7 1 1 0 -0.0019 11 0 0 0 2.44E+07 9.79E+06 - - - 5.3154 1 221125_WJC_METTL3_EV_vs_WT_F09.05045.05045.2 1.66E-05 14/18 K.DSDLSHVQNK[136.11].S "sp|O60506|HNRPQ_HUMAN,tr|A0A7I2YQV8|A0A7I2YQV8_HUMAN,tr|A0A7I2YQN2|A0A7I2YQN2_HUMAN,tr|A0A7I2V5Q6|A0A7I2V5Q6_HUMAN,tr|A0A7I2V4Z0|A0A7I2V4Z0_HUMAN,tr|A0A7I2V4J0|A0A7I2V4J0_HUMAN,tr|F6UXX1|F6UXX1_HUMAN,tr|A0A7I2V346|A0A7I2V346_HUMAN" 8 1149.5506 1.14 126668 5045 2 1149.549137 575.7826 Heterogeneous nuclear ribonucleoprotein Q OS=Homo sapiens OX=9606 GN=SYNCRIP PE=1 SV=2 5.21 1489.7 - 2.92E+06 - - - -1.2431 - 2.917 0.591 - 1010.3 1 2 0 -0.0014 10 0 0 0 2.47E+07 2.17E+07 - - - 6.3939 0.9998 221125_WJC_METTL3_EV_vs_WT_F09.05047.05047.2 0.00568 18-Dec R.K[136.11]IEVNNATAR[166.11].V "sp|O43251|RFOX2_HUMAN,sp|Q9NWB1|RFOX1_HUMAN,sp|A6NFN3|RFOX3_HUMAN,tr|A0A6Q8PGE0|A0A6Q8PGE0_HUMAN,tr|A0A6Q8PH77|A0A6Q8PH77_HUMAN,tr|A0A286YEU2|A0A286YEU2_HUMAN,tr|A0A087X2B1|A0A087X2B1_HUMAN,tr|F8VR27|F8VR27_HUMAN,tr|B7Z1U7|B7Z1U7_HUMAN,tr|B0QYV1|B0QYV1_HUMAN,tr|A0A6Q8PHA3|A0A6Q8PHA3_HUMAN,tr|A0A3B3ITL7|A0A3B3ITL7_HUMAN,tr|F8VZY7|F8VZY7_HUMAN,tr|B0QYY4|B0QYY4_HUMAN,tr|J3KNW3|J3KNW3_HUMAN,tr|F8VZG9|F8VZG9_HUMAN,tr|J3QRF4|J3QRF4_HUMAN,tr|F8VRS4|F8VRS4_HUMAN,tr|A0A6Q8PFM4|A0A6Q8PFM4_HUMAN,tr|S4R469|S4R469_HUMAN,tr|A0A804HKG7|A0A804HKG7_HUMAN,tr|A0A0G2JRD1|A0A0G2JRD1_HUMAN,tr|A0A0G2JRA5|A0A0G2JRA5_HUMAN,tr|A0A804HJM2|A0A804HJM2_HUMAN,tr|I3L1D4|I3L1D4_HUMAN,tr|S4R3K7|S4R3K7_HUMAN" 26 1132.6319 1.23 126670 5047 2 1132.630059 567.3232 RNA binding protein fox-1 homolog 2 OS=Homo sapiens OX=9606 GN=RBFOX2 PE=1 SV=3 8.75 1489.8 - 2.50E+06 - - - -1.6616 - 2.441 0.419 - 501.4 1 2 0 -0.0019 10 0 0 0 1.36E+07 1.11E+07 - - - 4.6261 0.9812 221125_WJC_METTL3_EV_vs_WT_F09.05048.05048.2 0.000371 13/16 A.SDSHR[166.11]PEVK[136.11].L "sp|Q9NYF8|BCLF1_HUMAN,tr|E9PKI6|E9PKI6_HUMAN,tr|A0A1W2PQ43|A0A1W2PQ43_HUMAN,tr|E9PK91|E9PK91_HUMAN,tr|E9PJA7|E9PJA7_HUMAN,tr|E9PK09|E9PK09_HUMAN,tr|E9PQN2|E9PQN2_HUMAN" 7 1071.5428 2.81 126671 5048 2 1071.541422 536.7787 Bcl-2-associated transcription factor 1 OS=Homo sapiens OX=9606 GN=BCLAF1 PE=1 SV=2 6.47 1489.9 - 1.71E+06 - - - -1.2785 - 2.277 0.333 - 789.1 1 1 0 -0.0014 9 0 0 0 1.85E+07 6.59E+06 - - - 3.8807 0.9926 221125_WJC_METTL3_EV_vs_WT_F09.05050.05050.2 3.88E-05 14/20 M.IASDSHRPEVK.L "sp|Q9NYF8|BCLF1_HUMAN,tr|E9PKI6|E9PKI6_HUMAN,tr|A0A1W2PQ43|A0A1W2PQ43_HUMAN,tr|E9PK91|E9PK91_HUMAN,tr|E9PJA7|E9PJA7_HUMAN,tr|E9PK09|E9PK09_HUMAN,tr|E9PQN2|E9PQN2_HUMAN" 7 1237.6415 2.16 126673 5050 2 1237.639738 619.828 Bcl-2-associated transcription factor 1 OS=Homo sapiens OX=9606 GN=BCLAF1 PE=1 SV=2 6.75 1490.2 - 1.50E+06 - - - -1.4229 - 2.734 0.525 - 670.8 1 1 0 -0.0018 11 0 0 0 6.50E+06 3.01E+06 - - - 5.6389 0.986 221125_WJC_METTL3_EV_vs_WT_F09.05054.05054.2 0.000361 14/20 M.IASDSHR[166.11]PEVK[136.11].L "sp|Q9NYF8|BCLF1_HUMAN,tr|E9PKI6|E9PKI6_HUMAN,tr|A0A1W2PQ43|A0A1W2PQ43_HUMAN,tr|E9PK91|E9PK91_HUMAN,tr|E9PJA7|E9PJA7_HUMAN,tr|E9PK09|E9PK09_HUMAN,tr|E9PQN2|E9PQN2_HUMAN" 7 1255.664 2.16 126677 5054 2 1255.661021 628.8393 Bcl-2-associated transcription factor 1 OS=Homo sapiens OX=9606 GN=BCLAF1 PE=1 SV=2 6.75 1490.6 - 611571 - - - -2.3478 - 2.719 0.521 - 586.8 1 1 0 -0.0029 11 0 0 0 6.50E+06 3.01E+06 - - - 5.5941 0.9998 221125_WJC_METTL3_EV_vs_WT_F09.05059.05059.2 1.78E-06 13/18 K.DSDLSHVQNK.S "sp|O60506|HNRPQ_HUMAN,tr|A0A7I2YQV8|A0A7I2YQV8_HUMAN,tr|A0A7I2YQN2|A0A7I2YQN2_HUMAN,tr|A0A7I2V5Q6|A0A7I2V5Q6_HUMAN,tr|A0A7I2V4Z0|A0A7I2V4Z0_HUMAN,tr|A0A7I2V4J0|A0A7I2V4J0_HUMAN,tr|F6UXX1|F6UXX1_HUMAN,tr|A0A7I2V346|A0A7I2V346_HUMAN" 8 1141.5364 1.14 126681 5059 2 1141.534278 571.7755 Heterogeneous nuclear ribonucleoprotein Q OS=Homo sapiens OX=9606 GN=SYNCRIP PE=1 SV=2 5.21 1491.2 - 7.76E+06 - - - -1.8291 - 2.824 0.42 - 978.1 1 2 0 -0.0021 10 0 0 0 2.47E+07 2.17E+07 - - - 5.0403 0.9852 221125_WJC_METTL3_EV_vs_WT_F09.05066.05066.3 0.329 15/56 K.LGASNSPGQPNSVKR.K sp|P49756|RBM25_HUMAN 1 1510.7852 1.19 126688 5066 3 1510.783296 504.6023 RNA-binding protein 25 OS=Homo sapiens OX=9606 GN=RBM25 PE=1 SV=3 11 1491.7 - 965367 - - - -1.2629 - 1.809 0.14 - 189.3 1 2 0 -0.0019 15 0 0 0 3.25E+06 2.73E+06 - - - 1.6471 0.901 221125_WJC_METTL3_EV_vs_WT_F09.05067.05067.3 0.104 Sep-48 R.EAAEEEGEPEVK[136.11]K[136.11].R sp|O95551|TYDP2_HUMAN 1 1459.7013 0.35 126689 5067 3 1459.696541 487.5744 Tyrosyl-DNA phosphodiesterase 2 OS=Homo sapiens OX=9606 GN=TDP2 PE=1 SV=1 4.21 1491.8 - 760432 - - - -3.2733 - 1.512 0.147 - 100.2 1 2 0 -0.0048 13 0 0 0 1.08E+06 3.13E+06 - - - 1.2985 1 221125_WJC_METTL3_EV_vs_WT_F09.05068.05068.2 8.57E-13 22/30 K.APEGGEGAQPVPGHAR.K "sp|Q6W2J9|BCOR_HUMAN,tr|H7BZ37|H7BZ37_HUMAN,tr|H7C2V9|H7C2V9_HUMAN,tr|H7BYY2|H7BYY2_HUMAN,tr|H7C231|H7C231_HUMAN" 5 1528.7383 2.36 126690 5068 2 1528.737785 765.3764 BCL-6 corepressor OS=Homo sapiens OX=9606 GN=BCOR PE=1 SV=1 5.4 1491.9 - 575196 - - - -0.3061 - 4.227 0.644 - 1451.1 1 2 0 -0.0005 16 0 0 0 2.94E+06 1.24E+06 - - - 7.3414 0.8637 221125_WJC_METTL3_EV_vs_WT_F09.05073.05073.2 0.0398 18-Jun N.VVTTPSTNRK.N "sp|Q8IWZ3|ANKH1_HUMAN,tr|E9PDP5|E9PDP5_HUMAN,tr|H0Y472|H0Y472_HUMAN,tr|H0Y4P6|H0Y4P6_HUMAN,tr|H0Y785|H0Y785_HUMAN" 5 1101.6142 1.93 126695 5073 2 1101.612633 551.8144 Ankyrin repeat and KH domain-containing protein 1 OS=Homo sapiens OX=9606 GN=ANKHD1 PE=1 SV=1 11 1492.5 - 341729 - - - -1.4424 - 1.223 0.311 - 117.5 1 1 0 -0.0016 10 0 0 0 2.92E+06 1.51E+06 - - - 1.8995 0.7965 221125_WJC_METTL3_EV_vs_WT_F09.05074.05074.2 0.0258 18-Jun N.VVTTPSTNR[166.11]K[136.11].N "sp|Q8IWZ3|ANKH1_HUMAN,tr|E9PDP5|E9PDP5_HUMAN,tr|H0Y472|H0Y472_HUMAN,tr|H0Y4P6|H0Y4P6_HUMAN,tr|H0Y785|H0Y785_HUMAN" 5 1119.6367 1.8 126696 5074 2 1119.633848 560.8256 Ankyrin repeat and KH domain-containing protein 1 OS=Homo sapiens OX=9606 GN=ANKHD1 PE=1 SV=1 11 1492.7 - 311530 - - - -2.5401 - 1.288 0.322 - 126.2 1 1 0 -0.0028 10 0 0 0 2.73E+06 1.51E+06 - - - 2.1249 0.9998 221125_WJC_METTL3_EV_vs_WT_F09.05078.05078.3 0.000936 Oct-44 R.NPPPNSDPNLRR.F sp|Q96I24|FUBP3_HUMAN 1 1375.6957 2.4 126698 5078 3 1375.694372 459.5725 Far upstream element-binding protein 3 OS=Homo sapiens OX=9606 GN=FUBP3 PE=1 SV=2 9.6 1493.2 - 2.58E+07 - - - -0.9363 - 1.848 0.374 - 94.1 1 2 0 -0.0013 12 0 0 0 3.25E+08 1.35E+08 - - - 4.4116 0.9783 221125_WJC_METTL3_EV_vs_WT_F09.05081.05081.3 0.000844 Dec-44 R.K[136.11]TQTPAAQPVPR[166.11].P "sp|Q6P1J9|CDC73_HUMAN,tr|A0A1B0GUB2|A0A1B0GUB2_HUMAN,tr|A0A3B3IRP5|A0A3B3IRP5_HUMAN" 3 1310.7426 1.2 126701 5081 3 1310.741453 437.9215 Parafibromin OS=Homo sapiens OX=9606 GN=CDC73 PE=1 SV=1 11 1493.3 - 4.68E+06 - - - -0.84 - 2.158 0.345 - 181.8 1 1 0 -0.0011 12 0 0 0 2.10E+07 1.75E+07 - - - 4.5182 1 221125_WJC_METTL3_EV_vs_WT_F09.05082.05082.2 1.55E-07 14/26 K.SPPSTGSTYGSSQK.E "sp|Q9Y2W1|TR150_HUMAN,tr|A0A3B3ITZ9|A0A3B3ITZ9_HUMAN" 2 1382.6314 2.86 126702 5082 2 1382.630151 692.323 Thyroid hormone receptor-associated protein 3 OS=Homo sapiens OX=9606 GN=THRAP3 PE=1 SV=2 8.31 1493.4 - 2.83E+06 - - - -0.8947 - 2.804 0.645 - 345.3 1 2 0 -0.0012 14 0 0 0 5.62E+08 1.97E+08 - - - 6.3919 1 221125_WJC_METTL3_EV_vs_WT_F09.05083.05083.3 1.69E-07 15/48 K.VGGTSDVEVNEKK.D "sp|P10809|CH60_HUMAN,tr|A0A7I2V2X6|A0A7I2V2X6_HUMAN,tr|A0A7I2YQK6|A0A7I2YQK6_HUMAN,tr|A0A7I2V599|A0A7I2V599_HUMAN" 4 1360.6834 0.76 126703 5083 3 1360.68214 454.5684 "60 kDa heat shock protein, mitochondrial OS=Homo sapiens OX=9606 GN=HSPD1 PE=1 SV=2" 4.68 1493.4 - 2.48E+06 - - - -0.9436 - 2.955 0.525 - 410.4 1 2 0 -0.0013 13 0 0 0 2.91E+08 3.85E+08 - - - 7.3306 0.9999 221125_WJC_METTL3_EV_vs_WT_F09.05084.05084.3 1.14E-05 Oct-36 R.DEDDADYK[136.11]PK[136.11].K "sp|P11387|TOP1_HUMAN,tr|A0A7P0T9R7|A0A7P0T9R7_HUMAN" 2 1210.5325 1.58 126704 5084 3 1210.530768 404.5181 DNA topoisomerase 1 OS=Homo sapiens OX=9606 GN=TOP1 PE=1 SV=2 4.04 1493.5 - 2.04E+06 - - - -1.3994 - 1.938 0.499 - 155 1 2 0 -0.0017 10 0 0 0 9.91E+06 6.29E+06 - - - 6.0352 0.9732 221125_WJC_METTL3_EV_vs_WT_F09.05086.05086.2 3.15 12-Sep M.YEEHLKR.M "sp|P84090|ERH_HUMAN,tr|G3V279|G3V279_HUMAN" 2 973.4981 2.08 126706 5086 2 973.497688 487.7563 Enhancer of rudimentary homolog OS=Homo sapiens OX=9606 GN=ERH PE=1 SV=1 6.76 1493.6 - 1.51E+06 - - - -0.454 - 1.745 0.315 - 406.6 1 1 0 -0.0004 7 0 0 0 1.29E+07 6.20E+06 - - - 3.1316 0.9895 221125_WJC_METTL3_EV_vs_WT_F09.05087.05087.3 8.21E-05 18/56 L.TALAAQQQAAGK[136.11]EEK[136.11].S sp|Q96A49|SYAP1_HUMAN 1 1558.8286 -1 126707 5087 3 1558.826566 520.6168 Synapse-associated protein 1 OS=Homo sapiens OX=9606 GN=SYAP1 PE=1 SV=1 5.81 1493.7 - 1.34E+06 - - - -1.2952 - 3.684 0.466 - 346.4 1 1 1 -0.002 15 0 0 0 0.00E+00 0.00E+00 - - - 7.1375 1 221125_WJC_METTL3_EV_vs_WT_F09.05088.05088.2 7.95E-08 17/26 K.SPPSTGSTYGSSQK[136.11].E "sp|Q9Y2W1|TR150_HUMAN,tr|A0A3B3ITZ9|A0A3B3ITZ9_HUMAN" 2 1390.6456 2.86 126708 5088 2 1390.644852 696.3301 Thyroid hormone receptor-associated protein 3 OS=Homo sapiens OX=9606 GN=THRAP3 PE=1 SV=2 8.31 1493.8 - 1.32E+06 - - - -0.5293 - 3.01 0.611 - 572 1 2 0 -0.0007 14 0 0 0 5.62E+08 1.97E+08 - - - 6.3189 1 221125_WJC_METTL3_EV_vs_WT_F09.05090.05090.2 0.000312 22-Nov R.SSSDNNTNTLGR[166.11].N "sp|Q9ULT8|HECD1_HUMAN,tr|A0A087X2H1|A0A087X2H1_HUMAN,tr|H0YJ72|H0YJ72_HUMAN,tr|H0YJP0|H0YJP0_HUMAN" 4 1274.5726 0.49 126710 5090 2 1274.572513 638.2936 E3 ubiquitin-protein ligase HECTD1 OS=Homo sapiens OX=9606 GN=HECTD1 PE=1 SV=3 5.55 1494.1 - 950706 - - - -0.1004 - 2.652 0.572 - 555.6 1 2 0 -0.0001 12 0 0 0 1.93E+06 3.97E+06 - - - 5.832 0.9995 221125_WJC_METTL3_EV_vs_WT_F09.05092.05092.2 0.000203 14-Sep K.MYEEHLKR.M "sp|P84090|ERH_HUMAN,tr|G3V279|G3V279_HUMAN" 2 1104.5386 2.6 126712 5092 2 1104.538874 553.2766 Enhancer of rudimentary homolog OS=Homo sapiens OX=9606 GN=ERH PE=1 SV=1 6.51 1494.3 - 802170 - - - 0.2354 - 2.165 0.236 - 470 1 2 0 0.0003 8 0 0 0 8.82E+06 3.40E+06 - - - 3.1136 0.9999 221125_WJC_METTL3_EV_vs_WT_F09.05103.05103.2 1.78E-05 24-Dec K.VGGTSDVEVNEK[136.11]K[136.11].D "sp|P10809|CH60_HUMAN,tr|A0A7I2V2X6|A0A7I2V2X6_HUMAN,tr|A0A7I2YQK6|A0A7I2YQK6_HUMAN,tr|A0A7I2V599|A0A7I2V599_HUMAN" 4 1376.7118 1 126722 5103 2 1376.710363 689.3632 "60 kDa heat shock protein, mitochondrial OS=Homo sapiens OX=9606 GN=HSPD1 PE=1 SV=2" 4.68 1495.3 - 3.75E+06 - - - -1.0612 - 2.7 0.556 - 533.9 1 2 0 -0.0015 13 0 0 0 2.18E+07 2.18E+07 - - - 5.6964 1 221125_WJC_METTL3_EV_vs_WT_F09.05105.05105.2 3.02E-05 17/24 K.VGGTSDVEVNEKK.D "sp|P10809|CH60_HUMAN,tr|A0A7I2V2X6|A0A7I2V2X6_HUMAN,tr|A0A7I2YQK6|A0A7I2YQK6_HUMAN,tr|A0A7I2V599|A0A7I2V599_HUMAN" 4 1360.6834 1 126724 5105 2 1360.683038 681.349 "60 kDa heat shock protein, mitochondrial OS=Homo sapiens OX=9606 GN=HSPD1 PE=1 SV=2" 4.68 1495.4 - 3.05E+06 - - - -0.2837 - 3.386 0.583 - 1597.9 1 2 0 -0.0004 13 0 0 0 2.18E+07 2.18E+07 - - - 6.4772 1 221125_WJC_METTL3_EV_vs_WT_F09.05108.05108.2 8.18E-14 15/24 K.TPNAQEAEGQQTR.A "sp|Q99865|SPI2A_HUMAN,sp|Q9BPZ2|SPI2B_HUMAN,tr|A0A087X074|A0A087X074_HUMAN,tr|Q5JZB8|Q5JZB8_HUMAN,tr|Q5JZB7|Q5JZB7_HUMAN" 5 1428.6593 4.29 126727 5108 2 1428.659332 715.3369 Spindlin-2A OS=Homo sapiens OX=9606 GN=SPIN2A PE=1 SV=3 4.53 1495.6 - 1.81E+06 - - - -0.0014 - 3.169 0.736 - 1128.3 1 2 0 0 13 0 0 0 6.50E+06 1.51E+06 - - - 7.4374 0.9917 221125_WJC_METTL3_EV_vs_WT_F09.05110.05110.2 6.89E-09 15/22 V.GGTSDVEVNEKK.D "sp|P10809|CH60_HUMAN,tr|A0A7I2V2X6|A0A7I2V2X6_HUMAN,tr|A0A7I2YQK6|A0A7I2YQK6_HUMAN,tr|A0A7I2V599|A0A7I2V599_HUMAN" 4 1261.615 -1 126729 5110 2 1261.613351 631.8148 "60 kDa heat shock protein, mitochondrial OS=Homo sapiens OX=9606 GN=HSPD1 PE=1 SV=2" 4.68 1495.8 - 1.79E+06 - - - -1.315 - 2.631 0.494 - 1074 1 1 0 -0.0017 12 0 0 0 0.00E+00 0.00E+00 - - - 5.2345 0.998 221125_WJC_METTL3_EV_vs_WT_F09.05113.05113.2 0.000722 14-Aug K.MYEEHLK[136.11]R[166.11].M "sp|P84090|ERH_HUMAN,tr|G3V279|G3V279_HUMAN" 2 1122.5611 2.6 126732 5113 2 1122.560868 562.2878 Enhancer of rudimentary homolog OS=Homo sapiens OX=9606 GN=ERH PE=1 SV=1 6.51 1496 - 1.55E+06 - - - -0.1924 - 1.75 0.141 - 313.4 1 2 0 -0.0002 8 0 0 0 8.82E+06 3.40E+06 - - - 1.7701 0.9938 221125_WJC_METTL3_EV_vs_WT_F09.05114.05114.2 0.00243 14/22 V.GGTSDVEVNEK[136.11]K[136.11].D "sp|P10809|CH60_HUMAN,tr|A0A7I2V2X6|A0A7I2V2X6_HUMAN,tr|A0A7I2YQK6|A0A7I2YQK6_HUMAN,tr|A0A7I2V599|A0A7I2V599_HUMAN" 4 1277.6434 1.12 126733 5114 2 1277.64316 639.829 "60 kDa heat shock protein, mitochondrial OS=Homo sapiens OX=9606 GN=HSPD1 PE=1 SV=2" 4.68 1496.1 - 1.38E+06 - - - -0.1957 - 2.624 0.48 - 833.3 1 1 0 -0.0003 12 0 0 0 9.94E+06 8.88E+06 - - - 5.1245 0.9989 221125_WJC_METTL3_EV_vs_WT_F09.05116.05116.2 0.0196 14-Aug K.YEDEINKR.T "sp|P48668|K2C6C_HUMAN,sp|P05787|K2C8_HUMAN,sp|Q01546|K22O_HUMAN,sp|Q7Z794|K2C1B_HUMAN,sp|P12035|K2C3_HUMAN,sp|P04264|K2C1_HUMAN,sp|P04259|K2C6B_HUMAN,sp|P13647|K2C5_HUMAN,sp|P35908|K22E_HUMAN,sp|O95678|K2C75_HUMAN,sp|P02538|K2C6A_HUMAN,tr|F8VUG2|F8VUG2_HUMAN,tr|F8W0C6|F8W0C6_HUMAN,tr|F8VP67|F8VP67_HUMAN,tr|F8W1U3|F8W1U3_HUMAN,tr|H0YIN9|H0YIN9_HUMAN" 16 1065.5091 -1 126735 5116 2 1065.507858 533.7618 "Keratin, type II cytoskeletal 6C OS=Homo sapiens OX=9606 GN=KRT6C PE=1 SV=3" 4.68 1496.3 - 913255 - - - -1.1544 - 1.47 0.308 - 211.2 1 2 0 -0.0012 8 0 0 0 0.00E+00 0.00E+00 - - - 2.4774 0.9868 221125_WJC_METTL3_EV_vs_WT_F09.05117.05117.2 0.00321 18-Nov P.PPNSDPNLRR.F sp|Q96I24|FUBP3_HUMAN 1 1164.6 2.29 126736 5117 2 1164.599827 583.3073 Far upstream element-binding protein 3 OS=Homo sapiens OX=9606 GN=FUBP3 PE=1 SV=2 10.03 1496.4 - 866954 - - - -0.1219 - 2.081 0.385 - 299.3 1 1 0 -0.0001 10 0 0 0 5.85E+06 2.56E+06 - - - 3.9302 0.7619 221125_WJC_METTL3_EV_vs_WT_F09.05121.05121.2 0.032 18-Aug P.PPNSDPNLR[166.11]R[166.11].F sp|Q96I24|FUBP3_HUMAN 1 1184.6165 2.4 126739 5121 2 1184.614678 593.3155 Far upstream element-binding protein 3 OS=Homo sapiens OX=9606 GN=FUBP3 PE=1 SV=2 10.03 1497 - 411039 - - - -1.5456 - 1.377 0.201 - 205.6 1 1 0 -0.0018 10 0 0 0 6.13E+06 2.56E+06 - - - 1.418 0.9999 221125_WJC_METTL3_EV_vs_WT_F09.05122.05122.3 2.75E-05 Nov-60 K.APEGGEGAQPVPGHAR[166.11].K "sp|Q6W2J9|BCOR_HUMAN,tr|H7BZ37|H7BZ37_HUMAN,tr|H7C2V9|H7C2V9_HUMAN,tr|H7BYY2|H7BYY2_HUMAN,tr|H7C231|H7C231_HUMAN" 5 1538.7465 2.02 126740 5122 3 1538.742605 513.9228 BCL-6 corepressor OS=Homo sapiens OX=9606 GN=BCOR PE=1 SV=1 5.4 1497.1 - 2.42E+06 - - - -2.5462 - 2.283 0.524 - 96.1 1 2 0 -0.0039 16 0 0 0 1.01E+08 4.98E+07 - - - 6.4991 0.9926 221125_WJC_METTL3_EV_vs_WT_F09.05126.05126.3 0.0567 Aug-44 K.NHVAAHGQSLLK.C sp|Q96JM3|CHAP1_HUMAN 1 1273.6891 0.39 126744 5126 3 1273.686674 425.5703 Chromosome alignment-maintaining phosphoprotein 1 OS=Homo sapiens OX=9606 GN=CHAMP1 PE=1 SV=2 8.76 1497.3 - 1.21E+06 - - - -1.9188 - 1.428 0.251 - 73.8 1 2 0 -0.0024 12 0 0 0 3.04E+06 7.79E+06 - - - 2.3253 0.9923 221125_WJC_METTL3_EV_vs_WT_F09.05127.05127.2 2.00E-06 20-Nov G.GTSDVEVNEKK.D "sp|P10809|CH60_HUMAN,tr|A0A7I2V2X6|A0A7I2V2X6_HUMAN,tr|A0A7I2YQK6|A0A7I2YQK6_HUMAN,tr|A0A7I2V599|A0A7I2V599_HUMAN" 4 1204.5935 1.05 126745 5127 2 1204.591857 603.304 "60 kDa heat shock protein, mitochondrial OS=Homo sapiens OX=9606 GN=HSPD1 PE=1 SV=2" 4.68 1497.4 - 1.16E+06 - - - -1.4021 - 2.579 0.529 - 614.7 1 1 0 -0.0017 11 0 0 0 3.07E+06 2.94E+06 - - - 5.5106 0.9994 221125_WJC_METTL3_EV_vs_WT_F09.05132.05132.2 0.00146 24-Dec R.RGFSDSGGGPPAK.Q "sp|Q9H307|PININ_HUMAN,tr|G3V5F0|G3V5F0_HUMAN,tr|G3V579|G3V579_HUMAN" 3 1231.5945 2.15 126750 5132 2 1231.592028 616.8046 Pinin OS=Homo sapiens OX=9606 GN=PNN PE=1 SV=5 8.75 1498 - 633914 - - - -2.0469 - 2.095 0.377 - 240.4 1 2 0 -0.0025 13 0 0 0 9.01E+06 4.19E+06 - - - 3.7228 1 221125_WJC_METTL3_EV_vs_WT_F09.05140.05140.2 1.34E-07 18/28 K.APTADTQTQNVNQAK.M sp|Q9Y5V3|MAGD1_HUMAN 1 1585.7696 1.57 126755 5140 2 1585.768373 793.8921 Melanoma-associated antigen D1 OS=Homo sapiens OX=9606 GN=MAGED1 PE=1 SV=3 5.88 1499 - 4.48E+06 - - - -0.782 - 3.701 0.633 - 1402.8 1 2 0 -0.0012 15 0 0 0 3.54E+07 2.25E+07 - - - 6.9332 0.9999 221125_WJC_METTL3_EV_vs_WT_F09.05142.05142.3 0.00406 13/36 K.VSR[166.11]PENEQLR[166.11].N "sp|Q8ND56|LS14A_HUMAN,tr|A0A140TA76|A0A140TA76_HUMAN,tr|K7EMZ9|K7EMZ9_HUMAN" 3 1246.6533 1.1 126757 5142 3 1246.652918 416.5584 Protein LSM14 homolog A OS=Homo sapiens OX=9606 GN=LSM14A PE=1 SV=3 6.11 1499.1 - 2.75E+06 - - - -0.2968 - 2.349 0.36 - 282.6 1 2 0 -0.0004 10 0 0 0 6.26E+07 5.72E+07 - - - 5.0476 0.9995 221125_WJC_METTL3_EV_vs_WT_F09.05145.05145.3 0.000401 Dec-56 K.APTADTQTQNVNQAK.M sp|Q9Y5V3|MAGD1_HUMAN 1 1585.7696 1.7 126760 5145 3 1585.769223 529.5971 Melanoma-associated antigen D1 OS=Homo sapiens OX=9606 GN=MAGED1 PE=1 SV=3 5.88 1499.3 - 1.50E+06 - - - -0.2459 - 1.837 0.333 - 162.4 1 2 0 -0.0004 15 0 0 0 9.13E+06 5.38E+06 - - - 3.8394 1 221125_WJC_METTL3_EV_vs_WT_F09.05151.05151.2 3.37E-09 24-Dec R.ATC[160.03]DC[160.03]PNC[160.03]QEAER.L "sp|Q8IXZ3|SP8_HUMAN,sp|P0CG40|SP9_HUMAN,tr|A0A087X0Q6|A0A087X0Q6_HUMAN" 3 1609.5919 1.35 126766 5151 2 1609.590513 805.8032 Transcription factor Sp8 OS=Homo sapiens OX=9606 GN=SP8 PE=1 SV=3 4.14 1500 - 598890 - - - -0.8779 - 2.677 0.8 - 393.3 1 2 0 -0.0014 13 0 0 0 5.70E+06 4.23E+06 - - - 7.4766 1 221125_WJC_METTL3_EV_vs_WT_F09.05154.05154.2 9.58E-09 24-Dec R.ATC[160.03]DC[160.03]PNC[160.03]QEAER[166.11].L "sp|Q8IXZ3|SP8_HUMAN,sp|P0CG40|SP9_HUMAN,tr|A0A087X0Q6|A0A087X0Q6_HUMAN" 3 1619.6002 1.35 126769 5154 2 1619.599013 810.8074 Transcription factor Sp8 OS=Homo sapiens OX=9606 GN=SP8 PE=1 SV=3 4.14 1500.3 - 488584 - - - -0.7304 - 2.682 0.757 - 406.1 1 2 0 -0.0012 13 0 0 0 5.70E+06 4.23E+06 - - - 7.1639 0.9996 221125_WJC_METTL3_EV_vs_WT_F09.05155.05155.3 0.00153 Dec-32 K.SHLNLDDR[166.11]R[166.11].W sp|Q5SY16|NOL9_HUMAN 1 1144.5852 0.001 126770 5155 3 1144.583531 382.5357 Polynucleotide 5'-hydroxyl-kinase NOL9 OS=Homo sapiens OX=9606 GN=NOL9 PE=1 SV=1 6.47 1500.4 - 386074 - - - -1.466 - 1.907 0.34 - 340.5 1 2 0 -0.0017 9 0 0 0 0.00E+00 2.87E+06 - - - 4.2757 0.9875 221125_WJC_METTL3_EV_vs_WT_F09.05161.05161.3 9.13E-05 Nov-40 L.DDSNRPASLTK.D "sp|Q9NYF8|BCLF1_HUMAN,tr|E9PKI6|E9PKI6_HUMAN,tr|A0A1W2PQ43|A0A1W2PQ43_HUMAN,tr|E9PK91|E9PK91_HUMAN,tr|E9PJA7|E9PJA7_HUMAN,tr|E9PK09|E9PK09_HUMAN,tr|E9PQN2|E9PQN2_HUMAN" 7 1202.5891 1.27 126774 5161 3 1202.588761 401.8703 Bcl-2-associated transcription factor 1 OS=Homo sapiens OX=9606 GN=BCLAF1 PE=1 SV=2 5.96 1501.3 - 4.58E+06 - - - -0.306 - 1.916 0.415 - 197.9 1 1 0 -0.0004 11 0 0 0 4.66E+07 3.67E+07 - - - 5.014 0.9988 221125_WJC_METTL3_EV_vs_WT_F09.05163.05163.3 0.000478 13/56 K.EVAGAK[136.11]PHITAAEGK[136.11].L "sp|Q16891|MIC60_HUMAN,tr|B9A067|B9A067_HUMAN,tr|C9J406|C9J406_HUMAN,tr|H7C463|H7C463_HUMAN" 4 1493.8173 1.61 126776 5163 3 1493.810907 498.9464 MICOS complex subunit MIC60 OS=Homo sapiens OX=9606 GN=IMMT PE=1 SV=1 6.85 1501.4 - 2.84E+06 - - - -4.2743 - 2.396 0.374 - 161.2 1 2 0 -0.0064 15 0 0 0 1.55E+07 9.60E+06 - - - 4.988 0.9996 221125_WJC_METTL3_EV_vs_WT_F09.05168.05168.2 0.00082 20-Aug R.DSPEENVQSNK.M "sp|Q8NDV7|TNR6A_HUMAN,tr|H7C269|H7C269_HUMAN" 2 1245.5473 2.43 126781 5168 2 1245.547295 623.7809 Trinucleotide repeat-containing gene 6A protein OS=Homo sapiens OX=9606 GN=TNRC6A PE=1 SV=2 4.14 1501.7 - 1.72E+06 - - - -0.0233 - 1.573 0.397 - 158.2 1 2 0 0 11 0 0 0 1.10E+07 4.53E+06 - - - 3.1987 0.9999 221125_WJC_METTL3_EV_vs_WT_F09.05171.05171.3 0.000214 13/56 K.APTADTQTQNVNQAK[136.11].M sp|Q9Y5V3|MAGD1_HUMAN 1 1593.7838 1.7 126784 5171 3 1593.780567 532.2685 Melanoma-associated antigen D1 OS=Homo sapiens OX=9606 GN=MAGED1 PE=1 SV=3 5.88 1501.9 - 1.18E+06 - - - -2.0367 - 2.542 0.455 - 337.7 1 2 0 -0.0032 15 0 0 0 9.13E+06 5.38E+06 - - - 6.0463 1 221125_WJC_METTL3_EV_vs_WT_F09.05175.05175.2 2.48E-06 15/26 K.SPQSDPADTPTNTK.Q sp|P46013|KI67_HUMAN 1 1457.6634 1.12 126788 5175 2 1457.661733 729.839 Proliferation marker protein Ki-67 OS=Homo sapiens OX=9606 GN=MKI67 PE=1 SV=2 4.21 1502.3 - 814094 - - - -1.1553 - 2.852 0.659 - 673.8 1 2 0 -0.0017 14 0 0 0 4.07E+06 3.62E+06 - - - 6.5378 0.9999 221125_WJC_METTL3_EV_vs_WT_F09.05176.05176.2 0.000322 20-Sep R.DSPEENVQSNK[136.11].M "sp|Q8NDV7|TNR6A_HUMAN,tr|H7C269|H7C269_HUMAN" 2 1253.5615 2.43 126789 5176 2 1253.56161 627.788 Trinucleotide repeat-containing gene 6A protein OS=Homo sapiens OX=9606 GN=TNRC6A PE=1 SV=2 4.14 1502.4 - 673832 - - - 0.0686 - 1.829 0.524 - 307.7 1 2 0 0.0001 11 0 0 0 1.10E+07 4.53E+06 - - - 4.5446 0.9762 221125_WJC_METTL3_EV_vs_WT_F09.05178.05178.2 8.89E-05 13/16 V.SR[166.11]PENEQLR[166.11].N "sp|Q8ND56|LS14A_HUMAN,tr|A0A140TA76|A0A140TA76_HUMAN,tr|K7EMZ9|K7EMZ9_HUMAN" 3 1147.5849 1.68 126791 5178 2 1147.58348 574.7997 Protein LSM14 homolog A OS=Homo sapiens OX=9606 GN=LSM14A PE=1 SV=3 5.86 1502.6 - 630373 - - - -1.2147 - 2.083 0.323 - 379.7 1 1 0 -0.0014 9 0 0 0 5.55E+06 3.31E+06 - - - 3.5492 1 221125_WJC_METTL3_EV_vs_WT_F09.05180.05180.2 0.0186 14/26 K.SPQSDPADTPTNTK[136.11].Q sp|P46013|KI67_HUMAN 1 1465.6776 1.12 126793 5180 2 1465.67784 733.8461 Proliferation marker protein Ki-67 OS=Homo sapiens OX=9606 GN=MKI67 PE=1 SV=2 4.21 1502.8 - 595372 - - - 0.1521 - 2.835 0.579 - 697.1 1 2 0 0.0002 14 0 0 0 4.07E+06 3.62E+06 - - - 5.9324 0.9999 221125_WJC_METTL3_EV_vs_WT_F09.05185.05185.2 4.16E-06 14-Nov K.KYYLHDDR.E "sp|Q9Y2W1|TR150_HUMAN,tr|A0A3B3ITZ9|A0A3B3ITZ9_HUMAN" 2 1108.5302 3.37 126797 5185 2 1108.530364 555.2724 Thyroid hormone receptor-associated protein 3 OS=Homo sapiens OX=9606 GN=THRAP3 PE=1 SV=2 6.75 1503.3 - 4.29E+06 - - - 0.1858 - 2.171 0.547 - 611.3 1 2 0 0.0002 8 0 0 0 2.12E+07 6.30E+06 - - - 5.419 0.9998 221125_WJC_METTL3_EV_vs_WT_F09.05187.05187.2 0.00455 13/18 K.VSRPENEQLR.N "sp|Q8ND56|LS14A_HUMAN,tr|A0A140TA76|A0A140TA76_HUMAN,tr|K7EMZ9|K7EMZ9_HUMAN" 3 1226.6367 1.03 126799 5187 2 1226.636923 614.3257 Protein LSM14 homolog A OS=Homo sapiens OX=9606 GN=LSM14A PE=1 SV=3 6.11 1503.5 - 1.26E+06 - - - 0.1427 - 2.247 0.351 - 279.1 1 2 0 0.0002 10 0 0 0 4.63E+06 4.48E+06 - - - 3.8933 0.9859 221125_WJC_METTL3_EV_vs_WT_F09.05188.05188.3 0.00595 Jul-44 M.DNADSSPVVDKR.E sp|Q86UP2|KTN1_HUMAN 1 1301.6212 1.19 126800 5188 3 1301.621141 434.881 Kinectin OS=Homo sapiens OX=9606 GN=KTN1 PE=1 SV=1 4.43 1503.5 - 1.17E+06 - - - -0.0131 - 1.661 0.445 - 75.9 1 1 0 0 12 0 0 0 7.95E+06 6.71E+06 - - - 4.9078 0.9998 221125_WJC_METTL3_EV_vs_WT_F09.05192.05192.2 0.00109 22-Dec K.VLGQPHHELDSK.T "sp|Q96DH6|MSI2H_HUMAN,tr|B4DHE8|B4DHE8_HUMAN,tr|A0A6Q8PF05|A0A6Q8PF05_HUMAN,tr|J3QKT5|J3QKT5_HUMAN,tr|A0A6Q8PFU8|A0A6Q8PFU8_HUMAN,tr|J3KTC1|J3KTC1_HUMAN,tr|A0A6Q8PHT3|A0A6Q8PHT3_HUMAN" 7 1358.6943 1.34 126804 5192 2 1358.69565 680.3544 RNA-binding protein Musashi homolog 2 OS=Homo sapiens OX=9606 GN=MSI2 PE=1 SV=1 5.99 1504 - 331188 - - - 1.0208 - 2.268 0.463 - 426.6 1 2 0 0.0014 12 0 0 0 2.78E+06 2.08E+06 - - - 4.6149 0.9998 221125_WJC_METTL3_EV_vs_WT_F09.05193.05193.2 0.00015 16-Sep K.HQTEDDFQR.E sp|Q15648|MED1_HUMAN 1 1174.5003 1.15 126805 5193 2 1174.501518 588.2574 Mediator of RNA polymerase II transcription subunit 1 OS=Homo sapiens OX=9606 GN=MED1 PE=1 SV=4 4.54 1504.1 - 287011 - - - 1.0251 - 1.75 0.484 - 221.8 1 2 0 0.0012 9 0 0 0 6.73E+05 5.83E+05 - - - 4.2344 0.9995 221125_WJC_METTL3_EV_vs_WT_F09.05202.05202.3 1.76E-05 Nov-44 K.HVVQSISTQQEK[136.11].E "sp|P24539|AT5F1_HUMAN,tr|Q5QNZ2|Q5QNZ2_HUMAN" 2 1390.7296 1.33 126812 5202 3 1390.729092 464.5838 "ATP synthase F(0) complex subunit B1, mitochondrial OS=Homo sapiens OX=9606 GN=ATP5PB PE=1 SV=2" 6.75 1505.1 - 5.46E+06 - - - -0.3602 - 2.072 0.292 - 221.7 1 2 0 -0.0005 12 0 0 0 3.07E+07 2.32E+07 - - - 3.8147 0.9999 221125_WJC_METTL3_EV_vs_WT_F09.05208.05208.2 0.00111 20-Dec R.KPNEGADGQWK.K sp|Q8NC51|PAIRB_HUMAN 1 1228.5837 0.51 126817 5208 2 1228.58428 615.2991 Plasminogen activator inhibitor 1 RNA-binding protein OS=Homo sapiens OX=9606 GN=SERBP1 PE=1 SV=2 6.07 1505.7 - 581875 - - - 0.5128 - 2.658 0.52 - 508.4 1 2 0 0.0006 11 0 0 0 3.35E+06 6.58E+06 - - - 5.5261 0.9992 221125_WJC_METTL3_EV_vs_WT_F09.05213.05213.2 0.0221 28-Jun K.APTADTQTQNVNQAK[136.11].M sp|Q9Y5V3|MAGD1_HUMAN 1 1593.7838 1.57 126822 5213 2 1593.782507 797.8992 Melanoma-associated antigen D1 OS=Homo sapiens OX=9606 GN=MAGED1 PE=1 SV=3 5.88 1506.3 - 336702 - - - -0.8194 - 1.292 0.407 - 72.2 1 2 0 -0.0013 15 0 0 0 3.54E+07 2.25E+07 - - - 2.6765 0.9988 221125_WJC_METTL3_EV_vs_WT_F09.05217.05217.3 0.000639 Dec-44 K.VLGQPHHELDSK[136.11].T "sp|Q96DH6|MSI2H_HUMAN,tr|B4DHE8|B4DHE8_HUMAN,tr|A0A6Q8PF05|A0A6Q8PF05_HUMAN,tr|J3QKT5|J3QKT5_HUMAN,tr|A0A6Q8PFU8|A0A6Q8PFU8_HUMAN,tr|J3KTC1|J3KTC1_HUMAN,tr|A0A6Q8PHT3|A0A6Q8PHT3_HUMAN" 7 1366.7085 1.46 126824 5217 3 1366.710426 456.5768 RNA-binding protein Musashi homolog 2 OS=Homo sapiens OX=9606 GN=MSI2 PE=1 SV=1 5.99 1506.8 - 1.97E+06 - - - 1.4363 - 2.307 0.227 - 241 1 2 0 0.002 12 0 0 0 5.60E+07 3.82E+07 - - - 3.3874 1 221125_WJC_METTL3_EV_vs_WT_F09.05219.05219.3 9.35E-05 Nov-36 R.RQVDQLTNDK.A "sp|P08670|VIME_HUMAN,tr|B0YJC4|B0YJC4_HUMAN" 2 1215.6208 1.88 126825 5219 3 1215.620464 406.2142 Vimentin OS=Homo sapiens OX=9606 GN=VIM PE=1 SV=4 5.96 1507 - 3.64E+06 - - - -0.2468 - 2.378 0.449 - 305.3 1 2 0 -0.0003 10 0 0 0 6.96E+08 3.71E+08 - - - 6.0757 0.9999 221125_WJC_METTL3_EV_vs_WT_F09.05220.05220.3 0.0128 Oct-36 R.R[166.11]QVDQLTNDK[136.11].A "sp|P08670|VIME_HUMAN,tr|B0YJC4|B0YJC4_HUMAN" 2 1233.6432 1.88 126826 5220 3 1233.64362 412.2217 Vimentin OS=Homo sapiens OX=9606 GN=VIM PE=1 SV=4 5.96 1507.1 - 2.75E+06 - - - 0.3129 - 2.224 0.375 - 273.9 1 2 0 0.0004 10 0 0 0 6.96E+08 3.71E+08 - - - 5.0551 0.9998 221125_WJC_METTL3_EV_vs_WT_F09.05221.05221.2 0.183 14/18 R.RQVDQLTNDK.A "sp|P08670|VIME_HUMAN,tr|B0YJC4|B0YJC4_HUMAN" 2 1215.6208 1.9 126827 5221 2 1215.61993 608.8177 Vimentin OS=Homo sapiens OX=9606 GN=VIM PE=1 SV=4 5.96 1507.1 - 2.46E+06 - - - -0.6861 - 2.7 0.313 - 781 1 2 0 -0.0008 10 0 0 0 5.58E+08 2.93E+08 - - - 4.125 0.9998 221125_WJC_METTL3_EV_vs_WT_F09.05222.05222.2 0.00163 15/18 R.R[166.11]QVDQLTNDK[136.11].A "sp|P08670|VIME_HUMAN,tr|B0YJC4|B0YJC4_HUMAN" 2 1233.6432 1.9 126828 5222 2 1233.642824 617.8289 Vimentin OS=Homo sapiens OX=9606 GN=VIM PE=1 SV=4 5.96 1507.2 - 1.90E+06 - - - -0.3323 - 2.541 0.326 - 735 1 2 0 -0.0004 10 0 0 0 5.58E+08 2.93E+08 - - - 4.0518 1 221125_WJC_METTL3_EV_vs_WT_F09.05224.05224.3 5.19E-05 Nov-36 K.RQITQNTDYR.L sp|Q92896|GSLG1_HUMAN 1 1293.6426 0.67 126830 5224 3 1293.643071 432.2215 Golgi apparatus protein 1 OS=Homo sapiens OX=9606 GN=GLG1 PE=1 SV=2 8.75 1507.4 - 907855 - - - 0.3935 - 2.211 0.458 - 249.1 1 2 0 0.0005 10 0 0 0 3.45E+06 5.15E+06 - - - 5.9633 0.9995 221125_WJC_METTL3_EV_vs_WT_F09.05227.05227.2 3.27E-05 13/20 R.K[136.11]PNEGADGQWK[136.11].K sp|Q8NC51|PAIRB_HUMAN 1 1244.612 0.51 126833 5227 2 1244.615105 623.3133 Plasminogen activator inhibitor 1 RNA-binding protein OS=Homo sapiens OX=9606 GN=SERBP1 PE=1 SV=2 6.07 1507.7 - 688602 - - - 2.4546 - 2.671 0.363 - 508.6 1 2 0 0.0031 11 0 0 0 3.35E+06 6.58E+06 - - - 4.3789 0.9998 221125_WJC_METTL3_EV_vs_WT_F09.05228.05228.2 0.00724 13/16 R.RSEPIYNSR.C sp|Q5T749|KPRP_HUMAN 1 1120.5625 999 126834 5228 2 1120.562131 561.2885 Keratinocyte proline-rich protein OS=Homo sapiens OX=9606 GN=KPRP PE=1 SV=1 8.75 1507.8 - 450478 - - - -0.348 - 2.357 0.32 - 333.8 1 2 0 -0.0004 9 0 0 0 6.93E+06 0.00E+00 - - - 3.8849 0.9923 221125_WJC_METTL3_EV_vs_WT_F09.05231.05231.3 0.226 13/52 R.QR[166.11]PPSGAGSVTPER[166.11].M sp|Q14703|MBTP1_HUMAN 1 1457.749 3 126837 5231 3 1457.746367 486.9236 Membrane-bound transcription factor site-1 protease OS=Homo sapiens OX=9606 GN=MBTPS1 PE=1 SV=1 9.6 1508.1 - 265006 - - - -1.7925 - 1.822 0.189 - 110.4 1 2 0 -0.0026 14 0 0 0 9.03E+06 3.01E+06 - - - 2.2408 0.8891 221125_WJC_METTL3_EV_vs_WT_F09.05232.05232.2 0.249 18-May K.QK[136.11]DTEPTNFK[136.11].V "sp|Q15003|CND2_HUMAN,tr|C9J470|C9J470_HUMAN,tr|E9PHA2|E9PHA2_HUMAN" 3 1222.6165 1.69 126838 5232 2 1222.616615 612.3155 Condensin complex subunit 2 OS=Homo sapiens OX=9606 GN=NCAPH PE=1 SV=3 6.07 1508.3 - 234553 - - - 0.1211 - 1.196 0.138 - 76.3 1 2 1 0.0001 10 0 0 0 3.01E+06 1.78E+06 - - - 0.5598 1 221125_WJC_METTL3_EV_vs_WT_F09.05233.05233.3 3.30E-05 Dec-56 K.K[136.11]GPGEVAGTVTGQK[136.11]R[166.11].R "sp|Q86U44|MTA70_HUMAN,tr|F5H6D8|F5H6D8_HUMAN,tr|H0YFV6|H0YFV6_HUMAN,tr|B4DTN4|B4DTN4_HUMAN" 4 1509.8474 0.001 126839 5233 3 1509.847781 504.2897 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 9.99 1508.4 - 208147 - - - 0.2788 - 2.468 0.455 - 189.7 1 2 0 0.0004 15 0 0 0 0.00E+00 2.93E+06 - - - 5.97 1 221125_WJC_METTL3_EV_vs_WT_F09.05242.05242.3 0.000255 17/40 K.QR[166.11]PQATAEQIR[166.11].L "sp|Q14157|UBP2L_HUMAN,tr|Q5VU78|Q5VU78_HUMAN,tr|F8W726|F8W726_HUMAN,tr|Q5VU81|Q5VU81_HUMAN,tr|Q5VU79|Q5VU79_HUMAN,tr|Q5VU80|Q5VU80_HUMAN,tr|Q5VU77|Q5VU77_HUMAN" 7 1316.7064 2.22 126846 5242 3 1316.704941 439.9094 Ubiquitin-associated protein 2-like OS=Homo sapiens OX=9606 GN=UBAP2L PE=1 SV=2 9.6 1509.3 - 1.79E+06 - - - -1.0982 - 2.956 0.39 - 736.3 1 2 0 -0.0014 11 0 0 0 7.96E+07 3.58E+07 - - - 5.9667 0.9999 221125_WJC_METTL3_EV_vs_WT_F09.05250.05250.3 0.00553 14/32 R.RFEKPLEEK.G sp|Q8NC51|PAIRB_HUMAN 1 1174.6346 0.71 126854 5250 3 1174.634176 392.5522 Plasminogen activator inhibitor 1 RNA-binding protein OS=Homo sapiens OX=9606 GN=SERBP1 PE=1 SV=2 6.23 1510.1 - 518916 - - - -0.3805 - 2.629 0.389 - 327.6 1 2 0 -0.0004 9 0 0 0 5.26E+07 7.39E+07 - - - 5.79 1 221125_WJC_METTL3_EV_vs_WT_F09.05257.05257.3 2.57E-05 14/48 K.IHNAENIQPGEQK[136.11].Y "sp|Q04637|IF4G1_HUMAN,tr|C9J2Z7|C9J2Z7_HUMAN,tr|E7EUU4|E7EUU4_HUMAN,tr|E9PGM1|E9PGM1_HUMAN,tr|C9J6B6|C9J6B6_HUMAN,tr|E7EX73|E7EX73_HUMAN,tr|C9K073|C9K073_HUMAN,tr|A0A7I2Y1C3|A0A7I2Y1C3_HUMAN,tr|C9JF13|C9JF13_HUMAN,tr|A0A6Q8PFB2|A0A6Q8PFB2_HUMAN" 10 1484.7463 0.96 126859 5257 3 1484.744753 495.9227 Eukaryotic translation initiation factor 4 gamma 1 OS=Homo sapiens OX=9606 GN=EIF4G1 PE=1 SV=4 5.4 1511 - 1.76E+06 - - - -1.0453 - 2.692 0.497 - 306.1 1 2 0 -0.0016 13 0 0 0 2.66E+07 2.77E+07 - - - 6.7656 0.9993 221125_WJC_METTL3_EV_vs_WT_F09.05261.05261.2 0.0193 14/18 R.R[166.11]QVDQLTNDK.A "sp|P08670|VIME_HUMAN,tr|B0YJC4|B0YJC4_HUMAN" 2 1225.629 - 126863 5261 2 1225.625743 613.8218 Vimentin OS=Homo sapiens OX=9606 GN=VIM PE=1 SV=4 5.96 1511.4 - 885164 - - - -2.6852 - 2.599 0.336 - 784.7 1 2 0 -0.0033 10 0 0 0 - - - - - 4.1877 0.9998 221125_WJC_METTL3_EV_vs_WT_F09.05265.05265.2 0.0026 20-Dec K.QR[166.11]PQATAEQIR[166.11].L "sp|Q14157|UBP2L_HUMAN,tr|Q5VU78|Q5VU78_HUMAN,tr|F8W726|F8W726_HUMAN,tr|Q5VU81|Q5VU81_HUMAN,tr|Q5VU79|Q5VU79_HUMAN,tr|Q5VU80|Q5VU80_HUMAN,tr|Q5VU77|Q5VU77_HUMAN" 7 1316.7064 2.28 126867 5265 2 1316.705653 659.3605 Ubiquitin-associated protein 2-like OS=Homo sapiens OX=9606 GN=UBAP2L PE=1 SV=2 9.6 1511.8 - 718287 - - - -0.5575 - 2.052 0.449 - 193.1 1 2 0 -0.0007 11 0 0 0 9.16E+06 4.02E+06 - - - 4.3016 0.9997 221125_WJC_METTL3_EV_vs_WT_F09.05266.05266.2 0.000441 16-Oct R.R[166.11]YDDPEVQK[136.11].D "sp|P38646|GRP75_HUMAN,tr|H0Y8K0|H0Y8K0_HUMAN,tr|A0A7I2V2S7|A0A7I2V2S7_HUMAN,tr|A0A7I2V2G2|A0A7I2V2G2_HUMAN,tr|A0A3B3ITI4|A0A3B3ITI4_HUMAN,tr|A0A7I2V3F7|A0A7I2V3F7_HUMAN,tr|A0A7I2YQB2|A0A7I2YQB2_HUMAN,tr|D6RCD7|D6RCD7_HUMAN" 8 1166.5687 0.64 126868 5266 2 1166.567054 584.2916 "Stress-70 protein, mitochondrial OS=Homo sapiens OX=9606 GN=HSPA9 PE=1 SV=2" 4.56 1511.9 - 697561 - - - -1.387 - 2.271 0.375 - 470.5 1 2 0 -0.0016 9 0 0 0 3.88E+06 6.02E+06 - - - 4.1832 0.9995 221125_WJC_METTL3_EV_vs_WT_F09.05267.05267.3 0.00028 Nov-36 R.K[136.11]QDSGHLDLR[166.11].N "sp|Q86U44|MTA70_HUMAN,tr|B4E349|B4E349_HUMAN,tr|F5H6D8|F5H6D8_HUMAN,tr|B4DTN4|B4DTN4_HUMAN" 4 1185.6221 0.05 126869 5267 3 1185.618612 396.2146 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 6.75 1512.1 - 561354 - - - -2.9461 - 2.115 0.373 - 157.7 1 2 0 -0.0035 10 0 0 0 5.60E+06 1.21E+08 - - - 4.8852 0.9619 221125_WJC_METTL3_EV_vs_WT_F09.05268.05268.2 0.395 16-Sep R.R[166.11]FEK[136.11]PLEEK[136.11].G sp|Q8NC51|PAIRB_HUMAN 1 1200.6713 0.87 126870 5268 2 1200.6679 601.3429 Plasminogen activator inhibitor 1 RNA-binding protein OS=Homo sapiens OX=9606 GN=SERBP1 PE=1 SV=2 6.23 1512.2 - 415494 - - - -2.8259 - 1.646 0.019 - 239.4 1 2 0 -0.0034 9 0 0 0 3.30E+06 3.80E+06 - - - 0.622 0.9993 221125_WJC_METTL3_EV_vs_WT_F09.05273.05273.2 0.000237 20-Oct K.QRPQATAEQIR.L "sp|Q14157|UBP2L_HUMAN,tr|Q5VU78|Q5VU78_HUMAN,tr|F8W726|F8W726_HUMAN,tr|Q5VU81|Q5VU81_HUMAN,tr|Q5VU79|Q5VU79_HUMAN,tr|Q5VU80|Q5VU80_HUMAN,tr|Q5VU77|Q5VU77_HUMAN" 7 1296.6898 2.28 126873 5273 2 1296.688303 649.3522 Ubiquitin-associated protein 2-like OS=Homo sapiens OX=9606 GN=UBAP2L PE=1 SV=2 9.6 1512.9 - 1.34E+06 - - - -1.1907 - 1.993 0.269 - 112.8 1 2 0 -0.0015 11 0 0 0 9.16E+06 4.02E+06 - - - 2.893 1 221125_WJC_METTL3_EV_vs_WT_F09.05284.05284.3 5.13E-06 15/40 R.QQPGPSEHIER.R "sp|P50552|VASP_HUMAN,tr|K7EQD0|K7EQD0_HUMAN" 2 1276.616 1.37 126882 5284 3 1276.615863 426.5459 Vasodilator-stimulated phosphoprotein OS=Homo sapiens OX=9606 GN=VASP PE=1 SV=3 5.4 1514.1 - 1.03E+06 - - - -0.1175 - 3.032 0.463 - 605.3 1 2 0 -0.0001 11 0 0 0 1.15E+07 8.37E+06 - - - 6.8531 0.9998 221125_WJC_METTL3_EV_vs_WT_F09.05287.05287.3 0.0366 Oct-36 K.TC[160.03]EESSFC[160.03]KR.Q sp|Q14697|GANAB_HUMAN 1 1302.5333 0.83 126885 5287 3 1302.52988 435.185 Neutral alpha-glucosidase AB OS=Homo sapiens OX=9606 GN=GANAB PE=1 SV=3 5.81 1514.4 - 652162 - - - -2.6034 - 1.937 0.471 - 177 1 2 0 -0.0034 10 0 0 0 6.81E+06 8.20E+06 - - - 5.7211 0.9999 221125_WJC_METTL3_EV_vs_WT_F09.05292.05292.2 3.18E-05 24-Oct K.IHNAENIQPGEQK[136.11].Y "sp|Q04637|IF4G1_HUMAN,tr|C9J2Z7|C9J2Z7_HUMAN,tr|E7EUU4|E7EUU4_HUMAN,tr|E9PGM1|E9PGM1_HUMAN,tr|C9J6B6|C9J6B6_HUMAN,tr|E7EX73|E7EX73_HUMAN,tr|C9K073|C9K073_HUMAN,tr|A0A7I2Y1C3|A0A7I2Y1C3_HUMAN,tr|C9JF13|C9JF13_HUMAN,tr|A0A6Q8PFB2|A0A6Q8PFB2_HUMAN" 10 1484.7463 0.42 126890 5292 2 1484.745987 743.3804 Eukaryotic translation initiation factor 4 gamma 1 OS=Homo sapiens OX=9606 GN=EIF4G1 PE=1 SV=4 5.4 1515 - 231106 - - - -0.2142 - 2.149 0.494 - 267.8 1 2 0 -0.0003 13 0 0 0 1.31E+06 3.09E+06 - - - 4.653 1 221125_WJC_METTL3_EV_vs_WT_F09.05297.05297.3 4.74E-05 Nov-40 R.QQPGPSEHIER[166.11].R "sp|P50552|VASP_HUMAN,tr|K7EQD0|K7EQD0_HUMAN" 2 1286.6243 1.71 126893 5297 3 1286.625014 429.882 Vasodilator-stimulated phosphoprotein OS=Homo sapiens OX=9606 GN=VASP PE=1 SV=3 5.4 1515.6 - 577274 - - - 0.5682 - 2.394 0.48 - 290.3 1 2 0 0.0007 11 0 0 0 1.12E+07 6.57E+06 - - - 6.3713 0.9927 221125_WJC_METTL3_EV_vs_WT_F09.05300.05300.3 2.35E-06 13/56 S.AAQKENAGEDPGLAR.Q sp|P81605|DCD_HUMAN 1 1525.7485 999 126896 5300 3 1525.749468 509.5901 Dermcidin OS=Homo sapiens OX=9606 GN=DCD PE=1 SV=2 4.68 1515.8 - 887894 - - - 0.6449 - 2.854 0.557 - 127.7 1 1 1 0.001 15 0 0 0 4.10E+06 0.00E+00 - - - 7.4862 0.9957 221125_WJC_METTL3_EV_vs_WT_F09.05304.05304.2 0.0193 16-Oct K.IKNDLNLKK.S sp|P15924|DESP_HUMAN 1 1084.6604 999 126900 5304 2 1084.661069 543.3375 Desmoplakin OS=Homo sapiens OX=9606 GN=DSP PE=1 SV=3 9.7 1516.3 - 394146 - - - 0.5762 - 1.992 0.323 - 211.9 1 2 1 0.0006 9 0 0 0 2.14E+06 0.00E+00 - - - 3.4202 1 221125_WJC_METTL3_EV_vs_WT_F09.05306.05306.2 5.70E-08 22-Nov K.SDTNNSGPEINK[136.11].L "sp|P42694|HELZ_HUMAN,tr|J3QS41|J3QS41_HUMAN" 2 1282.5881 2.32 126902 5306 2 1282.588271 642.3013 Probable helicase with zinc finger domain OS=Homo sapiens OX=9606 GN=HELZ PE=1 SV=2 4.37 1516.6 - 344066 - - - 0.1544 - 2.419 0.613 - 511.5 1 2 0 0.0002 12 0 0 0 3.83E+07 1.65E+07 - - - 5.8928 0.8849 221125_WJC_METTL3_EV_vs_WT_F09.05311.05311.2 5.04 24-Apr K.IHNAENIQPGEQK.Y "sp|Q04637|IF4G1_HUMAN,tr|C9J2Z7|C9J2Z7_HUMAN,tr|E7EUU4|E7EUU4_HUMAN,tr|E9PGM1|E9PGM1_HUMAN,tr|C9J6B6|C9J6B6_HUMAN,tr|E7EX73|E7EX73_HUMAN,tr|C9K073|C9K073_HUMAN,tr|A0A7I2Y1C3|A0A7I2Y1C3_HUMAN,tr|C9JF13|C9JF13_HUMAN,tr|A0A6Q8PFB2|A0A6Q8PFB2_HUMAN" 10 1476.7321 0.47 126907 5311 2 1476.73287 739.3733 Eukaryotic translation initiation factor 4 gamma 1 OS=Homo sapiens OX=9606 GN=EIF4G1 PE=1 SV=4 5.4 1517.2 - 193691 - - - 0.518 - 0.923 0.049 - 55.1 2 2 0 0.0008 13 0 0 0 1.31E+06 2.78E+06 - - - -0.9374 1 221125_WJC_METTL3_EV_vs_WT_F09.05313.05313.2 3.41E-11 16/30 R.AGAPADQGAEAADNQR.E sp|Q9H0W5|CCDC8_HUMAN 1 1540.6866 1.63 126909 5313 2 1540.686166 771.3506 Coiled-coil domain-containing protein 8 OS=Homo sapiens OX=9606 GN=CCDC8 PE=1 SV=2 4.03 1517.5 - 118909 - - - -0.2895 - 3.015 0.615 - 768.7 1 2 0 -0.0004 16 0 0 0 6.08E+06 3.73E+06 - - - 6.2965 0.9999 221125_WJC_METTL3_EV_vs_WT_F09.05317.05317.3 1.16E-06 14/32 R.RADDDRFPR.R sp|Q14152|EIF3A_HUMAN 1 1146.553 1.29 126911 5317 3 1146.553095 383.1916 Eukaryotic translation initiation factor 3 subunit A OS=Homo sapiens OX=9606 GN=EIF3A PE=1 SV=1 6.04 1517.9 - 2.06E+06 - - - 0.0663 - 2.397 0.513 - 432.8 1 2 1 0.0001 9 0 0 0 2.16E+07 1.68E+07 - - - 6.8941 0.9929 221125_WJC_METTL3_EV_vs_WT_F09.05322.05322.3 0.000397 Oct-48 K.ETQEDK[136.11]LEGGAAK[136.11].R "sp|O43491|E41L2_HUMAN,tr|A0A2R8Y5B3|A0A2R8Y5B3_HUMAN,tr|E9PII3|E9PII3_HUMAN,tr|E9PHY5|E9PHY5_HUMAN,tr|E9PK52|E9PK52_HUMAN" 5 1390.6911 0.82 126916 5322 3 1390.693765 464.571 Band 4.1-like protein 2 OS=Homo sapiens OX=9606 GN=EPB41L2 PE=1 SV=1 4.41 1518.3 - 1.09E+06 - - - 1.9249 - 1.858 0.289 - 110.2 1 2 1 0.0027 13 0 0 0 8.60E+06 1.05E+07 - - - 3.441 0.9998 221125_WJC_METTL3_EV_vs_WT_F09.05323.05323.3 5.59E-05 13/40 K.QRAEVLQSTQR.F "sp|Q9Y520|PRC2C_HUMAN,tr|E7EPN9|E7EPN9_HUMAN,tr|H7C5N8|H7C5N8_HUMAN,tr|A0A2R8YET2|A0A2R8YET2_HUMAN" 4 1314.7004 15.37 126917 5323 3 1314.701827 439.2407 Protein PRRC2C OS=Homo sapiens OX=9606 GN=PRRC2C PE=1 SV=4 9.6 1518.4 - 1.06E+06 - - - 1.0771 - 2.373 0.498 - 351.7 1 2 1 0.0014 11 0 0 0 2.55E+07 1.66E+06 - - - 6.5467 1 221125_WJC_METTL3_EV_vs_WT_F09.05324.05324.3 1.32E-08 17/60 R.AGAPADQGAEAADNQR.E sp|Q9H0W5|CCDC8_HUMAN 1 1540.6866 1.61 126918 5324 3 1540.687519 514.5695 Coiled-coil domain-containing protein 8 OS=Homo sapiens OX=9606 GN=CCDC8 PE=1 SV=2 4.03 1518.5 - 559824 - - - 0.5887 - 2.886 0.609 - 473.2 1 2 0 0.0009 16 0 0 0 3.92E+06 2.44E+06 - - - 8.049 0.9935 221125_WJC_METTL3_EV_vs_WT_F09.05328.05328.2 1.54E-05 24-Nov R.HGSGSGQSSSYGP.Y "sp|Q86YZ3|HORN_HUMAN,sp|Q86YZ3|HORN_HUMAN" 2 1206.4901 - 126922 5328 2 1206.489217 604.2523 Hornerin OS=Homo sapiens OX=9606 GN=HRNR PE=1 SV=2 6.74 1519 - 310420 - - - -0.7683 - 2.203 0.567 - 305.9 1 1 0 -0.0009 13 0 0 0 - - - - - 5.2557 0.9984 221125_WJC_METTL3_EV_vs_WT_F09.05329.05329.2 4.78E-05 20-Nov K.SSDRLDEAAQR.L sp|Q9HCS7|SYF1_HUMAN 1 1246.5902 1.2 126923 5329 2 1246.591482 624.3024 Pre-mRNA-splicing factor SYF1 OS=Homo sapiens OX=9606 GN=XAB2 PE=1 SV=2 4.56 1519.1 - 264366 - - - 1.0348 - 2.311 0.509 - 161.5 1 2 1 0.0013 11 0 0 0 1.86E+06 1.55E+06 - - - 5.0662 0.9768 221125_WJC_METTL3_EV_vs_WT_F09.05341.05341.3 0.263 Sep-32 R.GYFEHREDR.R "sp|Q9BUJ2|HNRL1_HUMAN,tr|M0R0K8|M0R0K8_HUMAN,tr|M0QYZ0|M0QYZ0_HUMAN,tr|A0A0A0MRA5|A0A0A0MRA5_HUMAN,tr|M0QZV6|M0QZV6_HUMAN,tr|M0R3F1|M0R3F1_HUMAN,tr|B7Z4B8|B7Z4B8_HUMAN,tr|M0QYI8|M0QYI8_HUMAN" 8 1207.537 1.41 126934 5341 3 1207.536477 403.5196 Heterogeneous nuclear ribonucleoprotein U-like protein 1 OS=Homo sapiens OX=9606 GN=HNRNPUL1 PE=1 SV=2 5.45 1520.2 - 1.95E+06 - - - -0.4613 - 1.257 0.268 - 134 1 2 1 -0.0006 9 0 0 0 1.76E+07 1.25E+07 - - - 2.2171 0.9951 221125_WJC_METTL3_EV_vs_WT_F09.05343.05343.2 0.00575 26-Sep R.ATSSSSGSLSATGR.L sp|Q03252|LMNB2_HUMAN 1 1267.6004 6.02 126936 5343 2 1267.603562 634.8075 Lamin-B2 OS=Homo sapiens OX=9606 GN=LMNB2 PE=1 SV=4 9.79 1520.5 - 451507 - - - 2.4771 - 1.994 0.184 - 135.5 2 2 0 0.0031 14 0 0 0 1.69E+06 2.80E+05 - - - 1.9964 0.9999 221125_WJC_METTL3_EV_vs_WT_F09.05345.05345.2 1.36E-05 13/26 R.VSGQPQSVTASSDK[136.11].A "sp|Q8N6T3|ARFG1_HUMAN,tr|F8VWH9|F8VWH9_HUMAN,tr|E5RHT6|E5RHT6_HUMAN,tr|F8W1U7|F8W1U7_HUMAN,tr|E5RHC5|E5RHC5_HUMAN" 5 1397.6878 1.27 126938 5345 2 1397.687988 699.8512 ADP-ribosylation factor GTPase-activating protein 1 OS=Homo sapiens OX=9606 GN=ARFGAP1 PE=1 SV=2 5.81 1520.7 - 329129 - - - 0.1438 - 2.225 0.499 - 434.6 1 2 0 0.0002 14 0 0 0 3.17E+06 2.49E+06 - - - 4.7335 1 221125_WJC_METTL3_EV_vs_WT_F09.05346.05346.2 1.64E-06 13/22 R.SSNADAEEK[136.11]LDR[166.11].S "sp|O60828|PQBP1_HUMAN,tr|A0A5H1ZRR1|A0A5H1ZRR1_HUMAN" 2 1351.6335 0.86 126939 5346 2 1351.634045 676.824 Polyglutamine-binding protein 1 OS=Homo sapiens OX=9606 GN=PQBP1 PE=1 SV=1 4.32 1520.8 - 248083 - - - 0.435 - 2.8 0.584 - 888.6 1 2 1 0.0006 12 0 0 0 9.34E+05 1.08E+06 - - - 6.0633 0.8673 221125_WJC_METTL3_EV_vs_WT_F09.05347.05347.2 0.00992 20-Jun K.QRAEVLQSTQR.F "sp|Q9Y520|PRC2C_HUMAN,tr|E7EPN9|E7EPN9_HUMAN,tr|H7C5N8|H7C5N8_HUMAN,tr|A0A2R8YET2|A0A2R8YET2_HUMAN" 4 1314.7004 -1 126940 5347 2 1314.696301 658.3575 Protein PRRC2C OS=Homo sapiens OX=9606 GN=PRRC2C PE=1 SV=4 9.6 1521 - 224806 - - - -3.1262 - 1.232 0.262 - 31.5 1 2 1 -0.0041 11 0 0 0 0.00E+00 0.00E+00 - - - 1.5393 0.9999 221125_WJC_METTL3_EV_vs_WT_F09.05359.05359.3 0.000256 17/56 K.LR[166.11]ESTPGDSPSTVNK[136.11].L sp|Q5T6F2|UBAP2_HUMAN 1 1604.8125 1.37 126950 5359 3 1604.814483 535.9448 Ubiquitin-associated protein 2 OS=Homo sapiens OX=9606 GN=UBAP2 PE=1 SV=1 6.07 1522.3 - 579255 - - - 1.2456 - 3.127 0.52 - 449.1 1 2 1 0.002 15 0 0 0 4.33E+06 3.17E+06 - - - 7.3118 1 221125_WJC_METTL3_EV_vs_WT_F09.05364.05364.2 2.22E-07 30-Nov K.GVPAGNSDTEGGQPGR[166.11].K "sp|Q9UKV3|ACINU_HUMAN,tr|G3V3B0|G3V3B0_HUMAN,tr|S4R3H4|S4R3H4_HUMAN,tr|E7EQT4|E7EQT4_HUMAN,tr|G3V3T3|G3V3T3_HUMAN" 5 1507.6891 1.65 126955 5364 2 1507.690167 754.8518 Apoptotic chromatin condensation inducer in the nucleus OS=Homo sapiens OX=9606 GN=ACIN1 PE=1 SV=2 4.37 1522.9 - 312274 - - - 0.7289 - 2.332 0.65 - 272.6 1 2 0 0.0011 16 0 0 0 1.70E+07 1.03E+07 - - - 5.9233 0.9984 221125_WJC_METTL3_EV_vs_WT_F09.05367.05367.3 0.0646 Aug-64 R.LPPSGSK[136.11]PVAASTC[160.03]SGK[136.11].K "sp|O43663|PRC1_HUMAN,tr|H3BSJ8|H3BSJ8_HUMAN,tr|H0YNE4|H0YNE4_HUMAN,tr|G3V3N7|G3V3N7_HUMAN" 4 1658.8633 0.69 126958 5367 3 1658.864216 553.9617 Protein regulator of cytokinesis 1 OS=Homo sapiens OX=9606 GN=PRC1 PE=1 SV=2 9.31 1523.3 - 245949 - - - 0.5787 - 1.625 0.29 - 68 1 2 0 0.001 17 0 0 0 2.96E+06 4.26E+06 - - - 2.9995 0.994 221125_WJC_METTL3_EV_vs_WT_F09.05369.05369.2 0.00323 28-Jul K.AEEAQK[136.11]TESVDNEGE.- sp|Q15651|HMGN3_HUMAN 1 1642.705 -1 126960 5369 2 1642.702879 822.3598 High mobility group nucleosome-binding domain-containing protein 3 OS=Homo sapiens OX=9606 GN=HMGN3 PE=1 SV=2 4.02 1523.6 - 209883 - - - -1.2632 - 1.645 0.405 - 117.8 1 2 1 -0.0021 15 0 0 0 0.00E+00 0.00E+00 - - - 3.2554 1 221125_WJC_METTL3_EV_vs_WT_F09.05370.05370.3 2.15E-06 22/64 R.ALGQAASDNSGPEDAKR.Q "sp|Q15155|NOMO1_HUMAN,sp|Q5JPE7|NOMO2_HUMAN,sp|P69849|NOMO3_HUMAN,tr|A0A7I2V3P4|A0A7I2V3P4_HUMAN,tr|A0A7I2V6B0|A0A7I2V6B0_HUMAN,tr|A0A7I2V4T6|A0A7I2V4T6_HUMAN,tr|A0A0G2JP90|A0A0G2JP90_HUMAN,tr|A0A087WTD5|A0A087WTD5_HUMAN,tr|A0A087X117|A0A087X117_HUMAN,tr|A0A0G2JN29|A0A0G2JN29_HUMAN,tr|A0A7I2V2Z5|A0A7I2V2Z5_HUMAN,tr|A0A087WW46|A0A087WW46_HUMAN,tr|H3BUC9|H3BUC9_HUMAN,tr|J3KN36|J3KN36_HUMAN" 14 1685.7969 1.72 126961 5370 3 1685.79668 562.9396 Nodal modulator 1 OS=Homo sapiens OX=9606 GN=NOMO1 PE=1 SV=5 4.56 1523.7 - 177897 - - - -0.1252 - 4.189 0.603 - 546.5 1 2 0 -0.0002 17 0 0 0 8.74E+06 5.08E+06 - - - 8.8816 0.9987 221125_WJC_METTL3_EV_vs_WT_F09.05371.05371.2 1.21E-06 28-Sep K.AEEAQKTESVDNEGE.- sp|Q15651|HMGN3_HUMAN 1 1634.6908 -1 126962 5371 2 1634.692336 818.3527 High mobility group nucleosome-binding domain-containing protein 3 OS=Homo sapiens OX=9606 GN=HMGN3 PE=1 SV=2 4.02 1523.8 - 142725 - - - 0.9678 - 2.435 0.575 - 197.3 1 2 1 0.0016 15 0 0 0 0.00E+00 0.00E+00 - - - 5.4754 1 221125_WJC_METTL3_EV_vs_WT_F09.05375.05375.2 1.07E-08 15/26 K.SPPSTGSTYGSSQK.E "sp|Q9Y2W1|TR150_HUMAN,tr|A0A3B3ITZ9|A0A3B3ITZ9_HUMAN" 2 1382.6314 2.88 126965 5375 2 1382.631097 692.323 Thyroid hormone receptor-associated protein 3 OS=Homo sapiens OX=9606 GN=THRAP3 PE=1 SV=2 8.31 1524.3 - 1.93E+06 - - - -0.2105 - 2.753 0.641 - 469.3 1 2 0 -0.0003 14 0 0 0 5.19E+08 1.80E+08 - - - 6.3166 0.9999 221125_WJC_METTL3_EV_vs_WT_F09.05376.05376.3 0.0094 15/36 R.LRAEIDNVKK.Q "sp|P13647|K2C5_HUMAN,tr|H0YI76|H0YI76_HUMAN" 2 1184.6877 999 126966 5376 3 1184.686356 395.9032 "Keratin, type II cytoskeletal 5 OS=Homo sapiens OX=9606 GN=KRT5 PE=1 SV=3" 8.59 1524.3 - 1.50E+07 - - - -1.1522 - 2.909 0.434 - 397.4 1 2 1 -0.0014 10 0 0 0 1.20E+08 0.00E+00 - - - 6.4968 0.9471 221125_WJC_METTL3_EV_vs_WT_F09.05377.05377.2 2.66 12-May K.EQSIVEK[136.11].F "sp|Q86U44|MTA70_HUMAN,tr|H0YFV6|H0YFV6_HUMAN" 2 839.448 0.03 126967 5377 2 839.446881 420.7313 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 4.53 1524.4 - 1.37E+07 - - - -1.3306 - 1.221 0.027 - 174.9 2 2 0 -0.0011 7 0 0 0 4.63E+06 1.50E+08 - - - -0.2617 0.9999 221125_WJC_METTL3_EV_vs_WT_F09.05378.05378.3 0.000304 13/44 K.TSGNATVDHLSK.Y sp|Q99496|RING2_HUMAN 1 1228.6048 1.87 126968 5378 3 1228.603168 410.5422 E3 ubiquitin-protein ligase RING2 OS=Homo sapiens OX=9606 GN=RNF2 PE=1 SV=1 6.41 1524.4 - 1.34E+07 - - - -1.3121 - 2.423 0.409 - 298.2 1 2 0 -0.0016 12 0 0 0 5.70E+07 3.04E+07 - - - 5.5526 1 221125_WJC_METTL3_EV_vs_WT_F09.05380.05380.3 6.07E-06 14/44 K.TSGNATVDHLSK[136.11].Y sp|Q99496|RING2_HUMAN 1 1236.619 1.87 126970 5380 3 1236.617149 413.2136 E3 ubiquitin-protein ligase RING2 OS=Homo sapiens OX=9606 GN=RNF2 PE=1 SV=1 6.41 1524.5 - 7.33E+06 - - - -1.4807 - 2.716 0.555 - 324.3 1 2 0 -0.0018 12 0 0 0 5.69E+07 3.04E+07 - - - 7.4967 0.9999 221125_WJC_METTL3_EV_vs_WT_F09.05384.05384.2 7.09E-10 15/30 K.GVPAGNSDTEGGQPGR.K "sp|Q9UKV3|ACINU_HUMAN,tr|G3V3B0|G3V3B0_HUMAN,tr|S4R3H4|S4R3H4_HUMAN,tr|E7EQT4|E7EQT4_HUMAN,tr|G3V3T3|G3V3T3_HUMAN" 5 1497.6808 1.62 126974 5384 2 1497.679386 749.8477 Apoptotic chromatin condensation inducer in the nucleus OS=Homo sapiens OX=9606 GN=ACIN1 PE=1 SV=2 4.37 1524.7 - 1.44E+06 - - - -0.9428 - 2.579 0.564 - 538.9 1 2 0 -0.0014 16 0 0 0 1.71E+07 1.05E+07 - - - 5.5355 0.9792 221125_WJC_METTL3_EV_vs_WT_F09.05386.05386.3 0.00445 Nov-32 R.R[166.11]ADDDR[166.11]FPR[166.11].R sp|Q14152|EIF3A_HUMAN 1 1176.5778 1.29 126976 5386 3 1176.575938 393.1999 Eukaryotic translation initiation factor 3 subunit A OS=Homo sapiens OX=9606 GN=EIF3A PE=1 SV=1 6.04 1524.9 - 1.17E+06 - - - -1.6072 - 1.938 0.176 - 243.5 1 2 1 -0.0019 9 0 0 0 2.16E+07 1.68E+07 - - - 2.4958 1 221125_WJC_METTL3_EV_vs_WT_F09.05389.05389.2 6.99E-07 15/24 R.TSGQTFANSNSSR[166.11].S sp|Q99661|KIF2C_HUMAN 1 1365.6148 0.9 126979 5389 2 1365.614024 683.8147 Kinesin-like protein KIF2C OS=Homo sapiens OX=9606 GN=KIF2C PE=1 SV=2 9.41 1525.2 - 707997 - - - -0.5975 - 2.654 0.604 - 947.2 1 2 0 -0.0008 13 0 0 0 2.67E+06 2.96E+06 - - - 6.007 0.9918 221125_WJC_METTL3_EV_vs_WT_F09.05393.05393.2 3.98E-06 15/26 K.SPPSTGSTYGSSQK[136.11].E "sp|Q9Y2W1|TR150_HUMAN,tr|A0A3B3ITZ9|A0A3B3ITZ9_HUMAN" 2 1390.6456 2.86 126983 5393 2 1390.636039 696.3301 Thyroid hormone receptor-associated protein 3 OS=Homo sapiens OX=9606 GN=THRAP3 PE=1 SV=2 8.31 1525.7 - 553338 - - - -6.8666 - 2.227 0.521 - 515.3 1 2 0 -0.0095 14 0 0 0 5.62E+08 1.97E+08 - - - 4.8953 1 221125_WJC_METTL3_EV_vs_WT_F09.05395.05395.3 1.11E-05 14/44 K.TGQSLATLHAHK[136.11].N sp|Q9C0J8|WDR33_HUMAN 1 1270.6873 1.43 126984 5395 3 1270.685039 424.5697 pre-mRNA 3' end processing protein WDR33 OS=Homo sapiens OX=9606 GN=WDR33 PE=1 SV=2 8.47 1525.9 - 2.76E+06 - - - -1.8061 - 2.894 0.472 - 360.8 1 2 0 -0.0023 12 0 0 0 1.16E+07 8.13E+06 - - - 6.7472 0.9961 221125_WJC_METTL3_EV_vs_WT_F09.05397.05397.2 0.139 18-Oct R.LRAEIDNVKK.Q "sp|P13647|K2C5_HUMAN,tr|H0YI76|H0YI76_HUMAN" 2 1184.6877 999 126986 5397 2 1184.685981 593.3511 "Keratin, type II cytoskeletal 5 OS=Homo sapiens OX=9606 GN=KRT5 PE=1 SV=3" 8.59 1526.1 - 2.14E+06 - - - -1.4687 - 1.938 0.407 - 270.6 1 2 1 -0.0017 10 0 0 0 7.01E+06 0.00E+00 - - - 3.8934 1 221125_WJC_METTL3_EV_vs_WT_F09.05404.05404.2 7.93E-06 28-Oct R.TTDGSLQNTSSEGSR.L "tr|A8MQB8|A8MQB8_HUMAN,tr|G3V0J0|G3V0J0_HUMAN" 2 1538.6809 1.99 126993 5404 2 1538.67981 770.3477 Synaptic functional regulator FMR1 OS=Homo sapiens OX=9606 GN=FMR1 PE=1 SV=1 4.37 1526.8 - 657899 - - - -0.6811 - 2.506 0.604 - 285.8 1 2 0 -0.001 15 0 0 0 5.91E+06 2.97E+06 - - - 5.7605 0.9945 221125_WJC_METTL3_EV_vs_WT_F09.05406.05406.2 1.80E-05 20-Dec T.SGNATVDHLSK.Y sp|Q99496|RING2_HUMAN 1 1127.5571 -1 126995 5406 2 1127.557073 564.7858 E3 ubiquitin-protein ligase RING2 OS=Homo sapiens OX=9606 GN=RNF2 PE=1 SV=1 6.46 1527.1 - 490671 - - - -0.0248 - 2.454 0.534 - 500.5 1 1 0 0 11 0 0 0 0.00E+00 0.00E+00 - - - 5.4137 0.9996 221125_WJC_METTL3_EV_vs_WT_F09.05407.05407.2 1.11E-06 13/22 R.KMDETDASSAVK.V "sp|Q13148|TADBP_HUMAN,tr|A0A087WX29|A0A087WX29_HUMAN,tr|G3V162|G3V162_HUMAN,tr|A0A087WYY0|A0A087WYY0_HUMAN,tr|K7EN94|K7EN94_HUMAN,tr|A0A0A0N0M3|A0A0A0N0M3_HUMAN,tr|B1AKP7|B1AKP7_HUMAN,tr|K7EJM5|K7EJM5_HUMAN,tr|A0A087X260|A0A087X260_HUMAN" 9 1280.5918 -1 126996 5407 2 1280.588011 641.3032 TAR DNA-binding protein 43 OS=Homo sapiens OX=9606 GN=TARDBP PE=1 SV=1 4.56 1527.2 - 472781 - - - -2.9838 - 2.427 0.538 - 403.7 1 2 0 -0.0038 12 0 0 0 0.00E+00 0.00E+00 - - - 5.3464 1 221125_WJC_METTL3_EV_vs_WT_F09.05413.05413.3 1.56E-09 13/48 R.C[160.03]GETGHVAINC[160.03]SK[136.11].T sp|P62633|CNBP_HUMAN 1 1439.6377 0.34 127001 5413 3 1439.635816 480.8865 CCHC-type zinc finger nucleic acid binding protein OS=Homo sapiens OX=9606 GN=CNBP PE=1 SV=1 6.73 1527.8 - 1.32E+07 - - - -1.2969 - 2.527 0.681 - 236.7 1 2 0 -0.0019 13 0 0 0 4.57E+07 1.36E+08 - - - 8.6454 0.9999 221125_WJC_METTL3_EV_vs_WT_F09.05416.05416.3 1.42E-06 23/64 R.ALGQAASDNSGPEDAK[136.11]R[166.11].Q "sp|Q15155|NOMO1_HUMAN,sp|Q5JPE7|NOMO2_HUMAN,sp|P69849|NOMO3_HUMAN,tr|A0A7I2V3P4|A0A7I2V3P4_HUMAN,tr|A0A7I2V6B0|A0A7I2V6B0_HUMAN,tr|A0A7I2V4T6|A0A7I2V4T6_HUMAN,tr|A0A0G2JP90|A0A0G2JP90_HUMAN,tr|A0A087WTD5|A0A087WTD5_HUMAN,tr|A0A087X117|A0A087X117_HUMAN,tr|A0A0G2JN29|A0A0G2JN29_HUMAN,tr|A0A7I2V2Z5|A0A7I2V2Z5_HUMAN,tr|A0A087WW46|A0A087WW46_HUMAN,tr|H3BUC9|H3BUC9_HUMAN,tr|J3KN36|J3KN36_HUMAN" 14 1703.8194 1.72 127004 5416 3 1703.812124 568.9471 Nodal modulator 1 OS=Homo sapiens OX=9606 GN=NOMO1 PE=1 SV=5 4.56 1528.1 - 1.10E+06 - - - -4.2475 - 3.591 0.576 - 602.2 1 2 0 -0.0072 17 0 0 0 8.74E+06 5.08E+06 - - - 8.1895 0.9999 221125_WJC_METTL3_EV_vs_WT_F09.05417.05417.2 1.31E-05 20-Dec K.SQEAQSLQQQR.D "sp|Q08379|GOGA2_HUMAN,tr|A0A6Q8KRG2|A0A6Q8KRG2_HUMAN,tr|A0A1W2PQY5|A0A1W2PQY5_HUMAN" 3 1301.6324 5.78 127005 5417 2 1301.630162 651.8235 Golgin subfamily A member 2 OS=Homo sapiens OX=9606 GN=GOLGA2 PE=1 SV=3 5.72 1528.2 - 367422 - - - -1.7125 - 2.517 0.56 - 734.2 1 2 0 -0.0022 11 0 0 0 4.14E+06 7.16E+05 - - - 5.6736 0.9998 221125_WJC_METTL3_EV_vs_WT_F09.05418.05418.2 8.10E-06 22-Nov K.KGPGLAVQSGDK.T sp|Q96PK6|RBM14_HUMAN 1 1155.6248 2.44 127006 5418 2 1155.623188 578.8197 RNA-binding protein 14 OS=Homo sapiens OX=9606 GN=RBM14 PE=1 SV=2 8.59 1528.3 - 208340 - - - -1.3837 - 2.278 0.5 - 266.7 1 2 0 -0.0016 12 0 0 0 1.25E+07 5.11E+06 - - - 4.8997 1 221125_WJC_METTL3_EV_vs_WT_F09.05422.05422.3 3.95E-05 17/48 R.VEAKPEVQSQPPR.V "sp|Q9UN86|G3BP2_HUMAN,tr|A0A7I2V3E2|A0A7I2V3E2_HUMAN,tr|A0A7I2V647|A0A7I2V647_HUMAN,tr|A0A7I2V3Z6|A0A7I2V3Z6_HUMAN,tr|A0A7I2YQD9|A0A7I2YQD9_HUMAN,tr|A0A7I2V382|A0A7I2V382_HUMAN,tr|A0A7I2V547|A0A7I2V547_HUMAN,tr|A0A7I2V3P9|A0A7I2V3P9_HUMAN" 8 1463.7732 1.56 127008 5422 3 1463.772394 488.9317 Ras GTPase-activating protein-binding protein 2 OS=Homo sapiens OX=9606 GN=G3BP2 PE=1 SV=2 6.11 1528.8 - 6.83E+06 - - - -0.5793 - 2.753 0.431 - 420.3 1 2 0 -0.0008 13 0 0 0 3.44E+08 2.20E+08 - - - 6.0907 0.999 221125_WJC_METTL3_EV_vs_WT_F09.05426.05426.2 0.00155 24-Aug K.EESAASGGAAYTK.R "sp|Q9Y2W1|TR150_HUMAN,tr|A0A3B3ITZ9|A0A3B3ITZ9_HUMAN" 2 1240.5572 4.47 127012 5426 2 1240.55607 621.2859 Thyroid hormone receptor-associated protein 3 OS=Homo sapiens OX=9606 GN=THRAP3 PE=1 SV=2 4.53 1529.1 - 600437 - - - -0.8794 - 1.554 0.312 - 146.4 1 2 0 -0.0011 13 0 0 0 3.29E+06 7.35E+05 - - - 2.4765 1 221125_WJC_METTL3_EV_vs_WT_F09.05428.05428.2 1.37E-06 16/22 K.K[136.11]GPGLAVQSGDK[136.11].T sp|Q96PK6|RBM14_HUMAN 1 1171.6532 2.44 127014 5428 2 1171.652245 586.8339 RNA-binding protein 14 OS=Homo sapiens OX=9606 GN=RBM14 PE=1 SV=2 8.59 1529.3 - 401729 - - - -0.804 - 2.831 0.555 - 682 1 2 0 -0.0009 12 0 0 0 1.25E+07 5.11E+06 - - - 5.878 0.8353 221125_WJC_METTL3_EV_vs_WT_F09.05429.05429.3 0.304 Sep-48 R.KQAANFTAGGQPR.R "sp|Q6RFH5|WDR74_HUMAN,tr|F5GYL6|F5GYL6_HUMAN" 2 1344.6898 2.05 127015 5429 3 1345.695159 449.2372 WD repeat-containing protein 74 OS=Homo sapiens OX=9606 GN=WDR74 PE=1 SV=1 11 1529.4 - 360359 - - - 747.6163 - 1.653 0.236 - 98.5 1 2 0 1.0053 13 0 0 0 8.83E+06 4.30E+06 - - - 2.2554 0.9988 221125_WJC_METTL3_EV_vs_WT_F09.05431.05431.2 0.000128 22-Sep K.EYSQMQQQNTQK[136.11].V "sp|Q8WUB8|PHF10_HUMAN,tr|S5FZ81|S5FZ81_HUMAN" 2 1519.6817 1.05 127017 5431 2 1519.676732 760.8481 PHD finger protein 10 OS=Homo sapiens OX=9606 GN=PHF10 PE=1 SV=3 6.1 1529.7 - 195643 - - - -3.2402 - 1.547 0.51 - 207.2 1 2 0 -0.0049 12 0 0 0 1.01E+06 9.65E+05 - - - 3.9543 0.998 221125_WJC_METTL3_EV_vs_WT_F09.05434.05434.2 0.082 20-Jun K.SQEAQSLQQQR[166.11].D "sp|Q08379|GOGA2_HUMAN,tr|A0A6Q8KRG2|A0A6Q8KRG2_HUMAN,tr|A0A1W2PQY5|A0A1W2PQY5_HUMAN" 3 1311.6407 -1 127020 5434 2 1311.639532 656.8276 Golgin subfamily A member 2 OS=Homo sapiens OX=9606 GN=GOLGA2 PE=1 SV=3 5.72 1530.1 - 152826 - - - -0.8608 - 1.419 0.256 - 130.2 1 2 0 -0.0011 11 0 0 0 0.00E+00 0.00E+00 - - - 1.8782 0.9999 221125_WJC_METTL3_EV_vs_WT_F09.05436.05436.3 0.00173 Aug-40 R.HMNGYGSHTFK.L sp|P04040|CATA_HUMAN 1 1277.5611 2.89 127021 5436 3 1277.559666 426.861 Catalase OS=Homo sapiens OX=9606 GN=CAT PE=1 SV=3 8.61 1530.4 - 669501 - - - -1.1545 - 1.406 0.56 - 47.8 1 2 0 -0.0015 11 0 0 0 6.02E+06 2.09E+06 - - - 5.751 0.9999 221125_WJC_METTL3_EV_vs_WT_F09.05438.05438.3 0.000142 13/44 K.K[136.11]GPGLAVQSGDK[136.11].T sp|Q96PK6|RBM14_HUMAN 1 1171.6532 1.94 127022 5438 3 1171.650686 391.5583 RNA-binding protein 14 OS=Homo sapiens OX=9606 GN=RBM14 PE=1 SV=2 8.59 1530.6 - 5.50E+06 - - - -2.1346 - 2.84 0.462 - 381.7 1 2 0 -0.0025 12 0 0 0 5.31E+07 2.74E+07 - - - 6.5834 1 221125_WJC_METTL3_EV_vs_WT_F09.05441.05441.2 3.70E-08 17/24 R.VEAKPEVQSQPPR.V "sp|Q9UN86|G3BP2_HUMAN,tr|A0A7I2V3E2|A0A7I2V3E2_HUMAN,tr|A0A7I2V647|A0A7I2V647_HUMAN,tr|A0A7I2V3Z6|A0A7I2V3Z6_HUMAN,tr|A0A7I2YQD9|A0A7I2YQD9_HUMAN,tr|A0A7I2V382|A0A7I2V382_HUMAN,tr|A0A7I2V547|A0A7I2V547_HUMAN,tr|A0A7I2V3P9|A0A7I2V3P9_HUMAN" 8 1463.7732 1.59 127025 5441 2 1463.773087 732.8939 Ras GTPase-activating protein-binding protein 2 OS=Homo sapiens OX=9606 GN=G3BP2 PE=1 SV=2 6.11 1531 - 1.04E+06 - - - -0.1059 - 2.752 0.605 - 645.6 1 2 0 -0.0002 13 0 0 0 1.21E+07 7.61E+06 - - - 6.1077 0.9995 221125_WJC_METTL3_EV_vs_WT_F09.05444.05444.3 0.203 Nov-40 R.KALEHVPNSVR.L sp|O94906|PRP6_HUMAN 1 1248.6939 1.94 127028 5444 3 1248.692316 417.2386 Pre-mRNA-processing factor 6 OS=Homo sapiens OX=9606 GN=PRPF6 PE=1 SV=1 8.75 1531.3 - 883198 - - - -1.2437 - 2.274 0.272 - 178.7 1 2 0 -0.0016 11 0 0 0 1.23E+07 6.34E+06 - - - 3.906 1 221125_WJC_METTL3_EV_vs_WT_F09.05445.05445.3 5.08E-09 13/40 K.SDC[160.03]KEFSSEAR.V "sp|Q12931|TRAP1_HUMAN,tr|I3L0K7|I3L0K7_HUMAN,tr|I3L239|I3L239_HUMAN,tr|I3L2D5|I3L2D5_HUMAN" 4 1314.551 2.5 127029 5445 3 1314.549953 439.191 "Heat shock protein 75 kDa, mitochondrial OS=Homo sapiens OX=9606 GN=TRAP1 PE=1 SV=3" 4.68 1531.4 - 762275 - - - -0.8193 - 2.663 0.694 - 334.5 1 2 1 -0.0011 11 0 0 0 1.13E+07 4.51E+06 - - - 9.0596 0.9669 221125_WJC_METTL3_EV_vs_WT_F09.05448.05448.2 0.00847 22-Nov V.EAKPEVQSQPPR.V "sp|Q9UN86|G3BP2_HUMAN,tr|A0A7I2V3E2|A0A7I2V3E2_HUMAN,tr|A0A7I2V647|A0A7I2V647_HUMAN,tr|A0A7I2V3Z6|A0A7I2V3Z6_HUMAN,tr|A0A7I2YQD9|A0A7I2YQD9_HUMAN,tr|A0A7I2V382|A0A7I2V382_HUMAN,tr|A0A7I2V547|A0A7I2V547_HUMAN,tr|A0A7I2V3P9|A0A7I2V3P9_HUMAN" 8 1364.7048 1.96 127032 5448 2 1364.702845 683.3597 Ras GTPase-activating protein-binding protein 2 OS=Homo sapiens OX=9606 GN=G3BP2 PE=1 SV=2 6.24 1531.8 - 467744 - - - -1.4531 - 1.744 0.381 - 211.1 1 1 0 -0.002 12 0 0 0 5.10E+06 2.60E+06 - - - 3.3179 0.9996 221125_WJC_METTL3_EV_vs_WT_F09.05455.05455.3 0.00164 17/36 K.IK[136.11]ELDHNISK[136.11].H sp|O95347|SMC2_HUMAN 1 1211.6845 0.98 127037 5455 3 1211.682527 404.9021 Structural maintenance of chromosomes protein 2 OS=Homo sapiens OX=9606 GN=SMC2 PE=1 SV=2 6.75 1532.6 - 1.51E+06 - - - -1.6176 - 2.975 0.351 - 278.4 1 2 1 -0.002 10 0 0 0 9.42E+06 9.61E+06 - - - 5.6368 0.9996 221125_WJC_METTL3_EV_vs_WT_F09.05456.05456.3 0.000212 Oct-40 K.SDC[160.03]K[136.11]EFSSEAR[166.11].V "sp|Q12931|TRAP1_HUMAN,tr|I3L0K7|I3L0K7_HUMAN,tr|I3L239|I3L239_HUMAN,tr|I3L2D5|I3L2D5_HUMAN" 4 1332.5735 2.5 127038 5456 3 1332.570842 445.1984 "Heat shock protein 75 kDa, mitochondrial OS=Homo sapiens OX=9606 GN=TRAP1 PE=1 SV=3" 4.68 1532.6 - 1.08E+06 - - - -1.9946 - 1.989 0.501 - 123.7 1 2 1 -0.0027 11 0 0 0 1.13E+07 4.51E+06 - - - 6.0784 0.9961 221125_WJC_METTL3_EV_vs_WT_F09.05457.05457.3 0.00827 13/36 K.IKELDHNISK.H sp|O95347|SMC2_HUMAN 1 1195.6561 0.99 127039 5457 3 1195.654087 399.5593 Structural maintenance of chromosomes protein 2 OS=Homo sapiens OX=9606 GN=SMC2 PE=1 SV=2 6.75 1532.7 - 975819 - - - -1.6727 - 2.082 0.27 - 158.4 1 2 1 -0.002 10 0 0 0 9.51E+06 9.61E+06 - - - 3.6913 1 221125_WJC_METTL3_EV_vs_WT_F09.05458.05458.2 0.000281 13/22 R.DSAQTSVTQAQR[166.11].E "sp|Q14980|NUMA1_HUMAN,tr|A0A087WY61|A0A087WY61_HUMAN,tr|F5H4J1|F5H4J1_HUMAN,tr|F5H6Y5|F5H6Y5_HUMAN" 4 1300.6247 0.81 127040 5458 2 1300.624572 651.3196 Nuclear mitotic apparatus protein 1 OS=Homo sapiens OX=9606 GN=NUMA1 PE=1 SV=2 5.84 1532.8 - 834950 - - - -0.0807 - 2.889 0.63 - 684.4 1 2 0 -0.0001 12 0 0 0 4.88E+06 6.05E+06 - - - 6.4856 0.998 221125_WJC_METTL3_EV_vs_WT_F09.05460.05460.3 0.000683 Nov-40 R.NPKPATVFSHK.N "sp|Q92643|GPI8_HUMAN,tr|A6NEM5|A6NEM5_HUMAN" 2 1224.6615 1.1 127042 5460 3 1224.658279 409.2278 GPI-anchor transamidase OS=Homo sapiens OX=9606 GN=PIGK PE=1 SV=2 10 1533.1 - 806556 - - - -2.6358 - 2.071 0.265 - 129.5 1 2 0 -0.0032 11 0 0 0 4.29E+06 3.88E+06 - - - 3.5618 0.9999 221125_WJC_METTL3_EV_vs_WT_F09.05461.05461.3 0.00305 13/48 R.VEAKPEVQSQPPR[166.11].V "sp|Q9UN86|G3BP2_HUMAN,tr|A0A7I2V3E2|A0A7I2V3E2_HUMAN,tr|A0A7I2V647|A0A7I2V647_HUMAN,tr|A0A7I2V3Z6|A0A7I2V3Z6_HUMAN,tr|A0A7I2YQD9|A0A7I2YQD9_HUMAN,tr|A0A7I2V382|A0A7I2V382_HUMAN,tr|A0A7I2V547|A0A7I2V547_HUMAN,tr|A0A7I2V3P9|A0A7I2V3P9_HUMAN" 8 1473.7815 - 127043 5461 3 1473.779778 492.2678 Ras GTPase-activating protein-binding protein 2 OS=Homo sapiens OX=9606 GN=G3BP2 PE=1 SV=2 6.11 1533.2 - 720523 - - - -1.1766 - 2.682 0.331 - 199.5 1 2 0 -0.0017 13 0 0 0 - - - - - 4.9047 0.9989 221125_WJC_METTL3_EV_vs_WT_F09.05462.05462.2 1.65E-05 14/24 K.ETEGDVTSVK[136.11]DAK[136.11].L sp|P50990|TCPQ_HUMAN 1 1393.6908 0.35 127044 5462 2 1393.690434 697.8527 T-complex protein 1 subunit theta OS=Homo sapiens OX=9606 GN=CCT8 PE=1 SV=4 4.32 1533.3 - 690614 - - - -0.2296 - 2.709 0.504 - 605.7 1 2 1 -0.0003 13 0 0 0 2.73E+06 7.79E+06 - - - 5.3212 0.9998 221125_WJC_METTL3_EV_vs_WT_F09.05466.05466.3 0.01 Oct-36 R.R[166.11]EQEQLNVEK[136.11].R "sp|Q15643|TRIPB_HUMAN,tr|H0YJ97|H0YJ97_HUMAN" 2 1289.6694 1.85 127048 5466 3 1289.669506 430.8971 Thyroid receptor-interacting protein 11 OS=Homo sapiens OX=9606 GN=TRIP11 PE=1 SV=3 4.79 1533.9 - 423250 - - - 0.0442 - 2.048 0.339 - 187.5 1 2 0 0.0001 10 0 0 0 1.01E+07 5.48E+06 - - - 4.4131 1 221125_WJC_METTL3_EV_vs_WT_F09.05471.05471.3 0.000729 17/40 K.HLNTEHALDDR[166.11].S "sp|Q8IVH2|FOXP4_HUMAN,tr|B7ZBM3|B7ZBM3_HUMAN" 2 1329.6301 2.95 127051 5471 3 1329.630514 444.2173 Forkhead box protein P4 OS=Homo sapiens OX=9606 GN=FOXP4 PE=1 SV=1 5.21 1534.4 - 1.37E+06 - - - 0.3136 - 2.51 0.514 - 340.9 1 2 0 0.0004 11 0 0 0 2.47E+07 8.37E+06 - - - 6.8848 0.9999 221125_WJC_METTL3_EV_vs_WT_F09.05472.05472.2 0.000199 13/22 R.NR[166.11]PPLPAGTNSK[136.11].G "sp|P42166|LAP2A_HUMAN,sp|P42167|LAP2B_HUMAN,tr|G5E972|G5E972_HUMAN" 3 1268.6956 1.26 127052 5472 2 1268.694689 635.3551 "Lamina-associated polypeptide 2, isoform alpha OS=Homo sapiens OX=9606 GN=TMPO PE=1 SV=2" 11 1534.6 - 1.04E+06 - - - -0.7212 - 2.675 0.491 - 547 1 2 0 -0.0009 12 0 0 0 2.14E+07 1.70E+07 - - - 5.2562 1 221125_WJC_METTL3_EV_vs_WT_F09.05473.05473.2 1.76E-07 17/22 R.NRPPLPAGTNSK.G "sp|P42166|LAP2A_HUMAN,sp|P42167|LAP2B_HUMAN,tr|G5E972|G5E972_HUMAN" 3 1250.6731 1.26 127053 5473 2 1250.670832 626.3438 "Lamina-associated polypeptide 2, isoform alpha OS=Homo sapiens OX=9606 GN=TMPO PE=1 SV=2" 11 1534.7 - 877303 - - - -1.8406 - 3.169 0.58 - 881.8 1 2 0 -0.0023 12 0 0 0 2.21E+07 1.75E+07 - - - 6.359 0.9999 221125_WJC_METTL3_EV_vs_WT_F09.05474.05474.2 4.03E-06 22-Dec R.DSAQTSVTQAQR.E "sp|Q14980|NUMA1_HUMAN,tr|A0A087WY61|A0A087WY61_HUMAN,tr|F5H4J1|F5H4J1_HUMAN,tr|F5H6Y5|F5H6Y5_HUMAN" 4 1290.6164 0.79 127054 5474 2 1290.615256 646.3155 Nuclear mitotic apparatus protein 1 OS=Homo sapiens OX=9606 GN=NUMA1 PE=1 SV=2 5.84 1534.8 - 734383 - - - -0.8918 - 2.209 0.551 - 495.8 1 2 0 -0.0012 12 0 0 0 4.80E+06 6.05E+06 - - - 5.1956 0.9822 221125_WJC_METTL3_EV_vs_WT_F09.05475.05475.3 0.0834 Oct-40 K.ETAKPKPDPFK.G "sp|O43823|AKAP8_HUMAN,tr|A0A7P0T893|A0A7P0T893_HUMAN" 2 1256.6765 1.08 127055 5475 3 1256.675269 419.8994 A-kinase anchor protein 8 OS=Homo sapiens OX=9606 GN=AKAP8 PE=1 SV=1 8.59 1534.9 - 728883 - - - -0.97 - 1.788 0.114 - 81.5 1 2 0 -0.0012 11 0 0 0 7.36E+06 6.85E+06 - - - 1.4615 0.9985 221125_WJC_METTL3_EV_vs_WT_F09.05485.05485.3 0.0281 Sep-36 K.VQVSYK[136.11]GETK[136.11].A "sp|P0DMV8|HS71A_HUMAN,sp|P0DMV9|HS71B_HUMAN,tr|A0A0G2JIW1|A0A0G2JIW1_HUMAN" 3 1153.6314 0.07 127063 5485 3 1153.631079 385.5511 Heat shock 70 kDa protein 1A OS=Homo sapiens OX=9606 GN=HSPA1A PE=1 SV=1 8.47 1536.1 - 1.15E+06 - - - -0.2687 - 1.848 0.345 - 136.4 1 2 1 -0.0003 10 0 0 0 4.79E+06 6.49E+07 - - - 4.1798 0.8491 221125_WJC_METTL3_EV_vs_WT_F09.05486.05486.2 0.00645 16-Oct Y.KSEITELRR.N "sp|P13645|K1C10_HUMAN,tr|A0A1B0GVI3|A0A1B0GVI3_HUMAN" 2 1130.6408 19.85 127064 5486 2 1130.639859 566.3277 "Keratin, type I cytoskeletal 10 OS=Homo sapiens OX=9606 GN=KRT10 PE=1 SV=6" 8.75 1536.2 - 675023 - - - -0.8066 - 1.83 0.106 - 200.1 1 1 0 -0.0009 9 0 0 0 4.47E+06 2.25E+05 - - - 1.5719 0.9993 221125_WJC_METTL3_EV_vs_WT_F09.05488.05488.2 0.00772 18-Sep R.R[166.11]EQEQLNVEK[136.11].R "sp|Q15643|TRIPB_HUMAN,tr|H0YJ97|H0YJ97_HUMAN" 2 1289.6694 1.13 127066 5488 2 1289.67091 645.842 Thyroid receptor-interacting protein 11 OS=Homo sapiens OX=9606 GN=TRIP11 PE=1 SV=3 4.79 1536.4 - 518425 - - - 1.1328 - 1.861 0.297 - 334.7 1 2 0 0.0015 10 0 0 0 4.34E+06 3.85E+06 - - - 2.9679 0.9061 221125_WJC_METTL3_EV_vs_WT_F09.05490.05490.2 1.46 18-Jul R.KFYTR[166.11]LTNSK[136.11].Q sp|Q9UP38|FZD1_HUMAN 1 1274.7102 - 127068 5490 2 1274.708918 638.3624 Frizzled-1 OS=Homo sapiens OX=9606 GN=FZD1 PE=1 SV=2 10.29 1536.7 - 249725 - - - -0.9987 - 1.57 0.068 - 129.9 1 2 1 -0.0013 10 0 0 0 - - - - - 0.8019 1 221125_WJC_METTL3_EV_vs_WT_F09.05496.05496.3 3.91E-05 14/52 K.ADAEGESDLENSRK.L sp|Q9Y490|TLN1_HUMAN 1 1519.675 0.83 127072 5496 3 1519.675705 507.5656 Talin-1 OS=Homo sapiens OX=9606 GN=TLN1 PE=1 SV=3 4.18 1537.3 - 956655 - - - 0.435 - 2.867 0.544 - 289.9 1 2 0 0.0007 14 0 0 0 8.62E+06 1.04E+07 - - - 7.404 0.9999 221125_WJC_METTL3_EV_vs_WT_F09.05497.05497.3 5.34E-05 13/48 R.ESVNQDKESQELR.K sp|Q5VUA4|ZN318_HUMAN 1 1560.738 1.15 127073 5497 3 1560.738047 521.2533 Zinc finger protein 318 OS=Homo sapiens OX=9606 GN=ZNF318 PE=1 SV=2 4.41 1537.5 - 914388 - - - 0.0436 - 2.65 0.476 - 300.5 1 2 1 0.0001 13 0 0 0 7.08E+06 6.17E+06 - - - 6.4892 1 221125_WJC_METTL3_EV_vs_WT_F09.05498.05498.3 9.26E-06 Dec-52 K.ADAEGESDLENSR[166.11]K[136.11].L sp|Q9Y490|TLN1_HUMAN 1 1537.6975 0.83 127074 5498 3 1537.698077 513.5731 Talin-1 OS=Homo sapiens OX=9606 GN=TLN1 PE=1 SV=3 4.18 1537.5 - 904884 - - - 0.3661 - 2.325 0.482 - 190 1 2 0 0.0006 14 0 0 0 8.62E+06 1.04E+07 - - - 6.1559 0.9999 221125_WJC_METTL3_EV_vs_WT_F09.05499.05499.3 1.44E-05 Dec-48 R.ESVNQDK[136.11]ESQELR[166.11].K sp|Q5VUA4|ZN318_HUMAN 1 1578.7604 1.15 127075 5499 3 1578.7607 527.2608 Zinc finger protein 318 OS=Homo sapiens OX=9606 GN=ZNF318 PE=1 SV=2 4.41 1537.7 - 730748 - - - 0.159 - 2.472 0.487 - 270.8 1 2 1 0.0003 13 0 0 0 7.08E+06 6.17E+06 - - - 6.4233 0.9997 221125_WJC_METTL3_EV_vs_WT_F09.05500.05500.3 0.00476 14/40 R.VRTELADKVTK.L sp|P35579|MYH9_HUMAN 1 1258.7245 0.85 127076 5500 3 1258.723946 420.5821 Myosin-9 OS=Homo sapiens OX=9606 GN=MYH9 PE=1 SV=4 8.56 1537.7 - 880962 - - - -0.4409 - 2.41 0.413 - 187.6 1 2 2 -0.0006 11 0 0 0 4.01E+06 4.75E+06 - - - 5.6433 0.9988 221125_WJC_METTL3_EV_vs_WT_F09.05513.05513.3 0.017 13/36 K.VQVSYKGETK.A "sp|P0DMV8|HS71A_HUMAN,sp|P0DMV9|HS71B_HUMAN,tr|A0A0G2JIW1|A0A0G2JIW1_HUMAN" 3 1137.603 0.07 127087 5513 3 1137.603539 380.2083 Heat shock 70 kDa protein 1A OS=Homo sapiens OX=9606 GN=HSPA1A PE=1 SV=1 8.47 1539.3 - 1.16E+06 - - - 0.4835 - 2.424 0.288 - 297.2 1 2 1 0.0006 10 0 0 0 4.79E+06 6.49E+07 - - - 4.3366 0.996 221125_WJC_METTL3_EV_vs_WT_F09.05514.05514.2 0.262 18-Oct K.VQVSYK[136.11]GETK[136.11].A "sp|P0DMV8|HS71A_HUMAN,sp|P0DMV9|HS71B_HUMAN,tr|A0A0G2JIW1|A0A0G2JIW1_HUMAN" 3 1153.6314 0.11 127088 5514 2 1153.631975 577.823 Heat shock 70 kDa protein 1A OS=Homo sapiens OX=9606 GN=HSPA1A PE=1 SV=1 8.47 1539.4 - 1.78E+06 - - - 0.508 - 1.955 0.348 - 370.1 1 2 1 0.0006 10 0 0 0 8.83E+05 8.26E+06 - - - 3.4824 0.9999 221125_WJC_METTL3_EV_vs_WT_F09.05515.05515.3 0.00047 Oct-44 R.SQR[166.11]PEESEPLEK[136.11].K sp|Q5TFE4|NT5D1_HUMAN 1 1445.7117 0.43 127089 5515 3 1445.712698 482.9112 5'-nucleotidase domain-containing protein 1 OS=Homo sapiens OX=9606 GN=NT5DC1 PE=1 SV=1 4.49 1539.4 - 751285 - - - 0.6848 - 2.222 0.417 - 162 1 2 0 0.001 12 0 0 0 1.78E+06 4.16E+06 - - - 5.4019 0.9499 221125_WJC_METTL3_EV_vs_WT_F09.05521.05521.2 0.394 18-Jul K.VQVSYKGETK.A "sp|P0DMV8|HS71A_HUMAN,sp|P0DMV9|HS71B_HUMAN,tr|A0A0G2JIW1|A0A0G2JIW1_HUMAN" 3 1137.603 -1 127094 5521 2 1137.60318 569.8088 Heat shock 70 kDa protein 1A OS=Homo sapiens OX=9606 GN=HSPA1A PE=1 SV=1 8.47 1540.1 - 204916 - - - 0.1679 - 1.547 0.122 - 206.7 1 2 1 0.0002 10 0 0 0 0.00E+00 0.00E+00 - - - 1.1599 0.9932 221125_WJC_METTL3_EV_vs_WT_F09.05530.05530.3 0.0734 Oct-36 K.IDDK[136.11]PVK[136.11]IDK[136.11].W "sp|Q15005|SPCS2_HUMAN,tr|H0YE04|H0YE04_HUMAN,tr|E9PI68|E9PI68_HUMAN,tr|A0A087WUC6|A0A087WUC6_HUMAN,tr|E9PL01|E9PL01_HUMAN" 5 1193.7082 1.22 127100 5530 3 1193.709011 398.91 Signal peptidase complex subunit 2 OS=Homo sapiens OX=9606 GN=SPCS2 PE=1 SV=3 6.04 1541.2 - 1.34E+06 - - - 0.6886 - 1.975 0.225 - 115.7 1 2 1 0.0008 10 0 0 0 7.07E+06 5.78E+06 - - - 3.0359 0.9986 221125_WJC_METTL3_EV_vs_WT_F09.05531.05531.3 0.000117 Nov-36 K.IDDKPVKIDK.W "sp|Q15005|SPCS2_HUMAN,tr|H0YE04|H0YE04_HUMAN,tr|E9PI68|E9PI68_HUMAN,tr|A0A087WUC6|A0A087WUC6_HUMAN,tr|E9PL01|E9PL01_HUMAN" 5 1169.6656 1.18 127101 5531 3 1169.666374 390.8958 Signal peptidase complex subunit 2 OS=Homo sapiens OX=9606 GN=SPCS2 PE=1 SV=3 6.04 1541.3 - 1.33E+06 - - - 0.6711 - 2.039 0.324 - 131 1 2 1 0.0008 10 0 0 0 7.13E+06 6.06E+06 - - - 4.2328 0.9997 221125_WJC_METTL3_EV_vs_WT_F09.05533.05533.3 0.00273 Nov-40 R.K[136.11]SPSVSLSQSK[136.11].E "sp|Q5VT06|CE350_HUMAN,tr|H0Y6Q4|H0Y6Q4_HUMAN" 2 1162.6529 2.01 127103 5533 3 1162.653305 388.5582 Centrosome-associated protein 350 OS=Homo sapiens OX=9606 GN=CEP350 PE=1 SV=1 10 1541.4 - 905788 - - - 0.3896 - 2.035 0.33 - 201.4 1 2 0 0.0005 11 0 0 0 8.54E+06 4.25E+06 - - - 4.2374 0.8226 221125_WJC_METTL3_EV_vs_WT_F09.05536.05536.3 0.689 May-44 R.SSEPVQHEESIR.K "sp|Q9UDY2|ZO2_HUMAN,tr|A0A2R8YDH4|A0A2R8YDH4_HUMAN,tr|A0A1B0GTW1|A0A1B0GTW1_HUMAN,tr|A0A3B3IRI3|A0A3B3IRI3_HUMAN,tr|A0A3B3ITE1|A0A3B3ITE1_HUMAN" 5 1396.6583 1.49 127106 5536 3 1396.657453 466.56 Tight junction protein ZO-2 OS=Homo sapiens OX=9606 GN=TJP2 PE=1 SV=2 4.75 1541.7 - 546276 - - - -0.5864 - 1.178 0.157 - 18.2 26 2 0 -0.0008 12 0 0 0 6.50E+06 4.37E+06 - - - 0.0894 0.9981 221125_WJC_METTL3_EV_vs_WT_F09.05538.05538.3 1.77E-06 Oct-64 R.GPYESGSGHSSGLGHQE.S sp|Q86YZ3|HORN_HUMAN 1 1684.7077 - 127108 5538 3 1684.709436 562.5765 Hornerin OS=Homo sapiens OX=9606 GN=HRNR PE=1 SV=2 5.37 1541.9 - 418049 - - - 1.0061 - 2.392 0.594 - 62.4 1 1 0 0.0017 17 0 0 0 - - - - - 7.3653 0.9998 221125_WJC_METTL3_EV_vs_WT_F09.05541.05541.2 0.000687 13/20 R.KSPSVSLSQSK.E "sp|Q5VT06|CE350_HUMAN,tr|H0Y6Q4|H0Y6Q4_HUMAN" 2 1146.6245 1.84 127111 5541 2 1146.626609 574.3195 Centrosome-associated protein 350 OS=Homo sapiens OX=9606 GN=CEP350 PE=1 SV=1 10 1542.2 - 320297 - - - 1.8812 - 2.575 0.467 - 552.8 1 2 0 0.0022 11 0 0 0 2.01E+06 1.09E+06 - - - 5.0483 0.9977 221125_WJC_METTL3_EV_vs_WT_F09.05543.05543.3 0.0204 Aug-60 R.GSSPGPR[166.11]PVEGTPASR[166.11].T sp|Q13112|CAF1B_HUMAN 1 1570.7967 -1 127113 5543 3 1570.793846 524.6062 Chromatin assembly factor 1 subunit B OS=Homo sapiens OX=9606 GN=CHAF1B PE=1 SV=1 9.6 1542.5 - 241456 - - - -1.7902 - 1.652 0.289 - 59.5 1 2 0 -0.0028 16 0 0 0 0.00E+00 0.00E+00 - - - 3.0493 0.9793 221125_WJC_METTL3_EV_vs_WT_F09.05552.05552.3 0.0226 Aug-32 K.FKYDDAERR.F "sp|P29692|EF1D_HUMAN,tr|E9PI39|E9PI39_HUMAN,tr|E9PMW7|E9PMW7_HUMAN,tr|E9PKK3|E9PKK3_HUMAN,tr|E9PQ49|E9PQ49_HUMAN,tr|A0A087X1X7|A0A087X1X7_HUMAN,tr|E9PL12|E9PL12_HUMAN,tr|E9PK72|E9PK72_HUMAN,tr|H0YCK7|H0YCK7_HUMAN,tr|E9PQZ1|E9PQZ1_HUMAN,tr|E9PK06|E9PK06_HUMAN,tr|E9PIZ1|E9PIZ1_HUMAN,tr|E9PN91|E9PN91_HUMAN,tr|E9PNW6|E9PNW6_HUMAN,tr|E9PPR1|E9PPR1_HUMAN,tr|E9PRY8|E9PRY8_HUMAN,tr|E9PK01|E9PK01_HUMAN,tr|E9PJD0|E9PJD0_HUMAN,tr|E9PL71|E9PL71_HUMAN" 19 1198.5731 1.99 127121 5552 3 1198.574148 400.5316 Elongation factor 1-delta OS=Homo sapiens OX=9606 GN=EEF1D PE=1 SV=5 6.12 1543.5 - 1.53E+06 - - - 0.8869 - 1.482 0.233 - 97.1 1 2 1 0.0011 9 0 0 0 8.30E+06 4.17E+06 - - - 2.323 0.973 221125_WJC_METTL3_EV_vs_WT_F09.05553.05553.3 0.0373 Aug-32 K.FK[136.11]YDDAER[166.11]R[166.11].F "sp|P29692|EF1D_HUMAN,tr|E9PI39|E9PI39_HUMAN,tr|E9PMW7|E9PMW7_HUMAN,tr|E9PKK3|E9PKK3_HUMAN,tr|E9PQ49|E9PQ49_HUMAN,tr|A0A087X1X7|A0A087X1X7_HUMAN,tr|E9PL12|E9PL12_HUMAN,tr|E9PK72|E9PK72_HUMAN,tr|H0YCK7|H0YCK7_HUMAN,tr|E9PQZ1|E9PQZ1_HUMAN,tr|E9PK06|E9PK06_HUMAN,tr|E9PIZ1|E9PIZ1_HUMAN,tr|E9PN91|E9PN91_HUMAN,tr|E9PNW6|E9PNW6_HUMAN,tr|E9PPR1|E9PPR1_HUMAN,tr|E9PRY8|E9PRY8_HUMAN,tr|E9PK01|E9PK01_HUMAN,tr|E9PJD0|E9PJD0_HUMAN,tr|E9PL71|E9PL71_HUMAN" 19 1226.6038 1.99 127122 5553 3 1226.605855 409.8752 Elongation factor 1-delta OS=Homo sapiens OX=9606 GN=EEF1D PE=1 SV=5 6.12 1543.5 - 1.14E+06 - - - 1.655 - 1.475 0.254 - 88.4 2 2 1 0.002 9 0 0 0 8.30E+06 4.17E+06 - - - 2.4033 1 221125_WJC_METTL3_EV_vs_WT_F09.05554.05554.2 8.07E-06 17/30 R.GGSGGSHGGGSGFGGE.S "sp|P35527|K1C9_HUMAN,tr|K7EQQ3|K7EQQ3_HUMAN" 2 1262.4912 - 127123 5554 2 1262.492254 632.2529 "Keratin, type I cytoskeletal 9 OS=Homo sapiens OX=9606 GN=KRT9 PE=1 SV=3" 5.47 1543.6 - 1.12E+06 - - - 0.8301 - 3.039 0.613 - 664 1 1 0 0.001 16 0 0 0 - - - - - 6.301 0.9998 221125_WJC_METTL3_EV_vs_WT_F09.05556.05556.2 0.0214 18-Nov R.KYTEQITNEK.L "sp|Q16718|NDUA5_HUMAN,tr|C9IZN5|C9IZN5_HUMAN,tr|H7BYD0|H7BYD0_HUMAN,tr|A0A087X1G1|A0A087X1G1_HUMAN,tr|F8WAS3|F8WAS3_HUMAN,tr|A0A7I2V2W4|A0A7I2V2W4_HUMAN,tr|A0A7I2V3L8|A0A7I2V3L8_HUMAN" 7 1252.6299 3.3 127125 5556 2 1252.629443 627.3222 NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 5 OS=Homo sapiens OX=9606 GN=NDUFA5 PE=1 SV=3 6.14 1543.9 - 605910 - - - -0.3904 - 2.104 0.387 - 417.3 1 2 0 -0.0005 10 0 0 0 3.36E+06 1.02E+06 - - - 3.9755 0.946 221125_WJC_METTL3_EV_vs_WT_F09.05557.05557.2 0.574 20-Jul K.GSRVPSKEDDK.E "sp|O43424|GRID2_HUMAN,tr|A0A087X043|A0A087X043_HUMAN" 2 1216.6048 999 127126 5557 2 1216.604463 609.3097 "Glutamate receptor ionotropic, delta-2 OS=Homo sapiens OX=9606 GN=GRID2 PE=1 SV=2" 6.12 1544 - 523891 - - - -0.2606 - 1.641 0.096 - 133.6 1 2 2 -0.0003 11 0 0 0 2.65E+06 0.00E+00 - - - 1.0899 1 221125_WJC_METTL3_EV_vs_WT_F09.05558.05558.3 4.78E-08 13/52 K.HMAAASAEC[160.03]QNYAK[136.11].E "sp|Q9P2E9|RRBP1_HUMAN,tr|A0A087WU26|A0A087WU26_HUMAN,tr|A0A087WVV2|A0A087WVV2_HUMAN,tr|F8W7S5|F8W7S5_HUMAN" 4 1558.6748 1.01 127127 5558 3 1558.675489 520.5655 Ribosome-binding protein 1 OS=Homo sapiens OX=9606 GN=RRBP1 PE=1 SV=5 6.74 1544.2 - 449921 - - - 0.444 - 2.651 0.556 - 321.6 1 2 0 0.0007 14 0 0 0 3.77E+06 3.72E+06 - - - 7.3296 1 221125_WJC_METTL3_EV_vs_WT_F09.05559.05559.2 6.29E-11 19/34 K.NQGGGLSSSGAGEGQGPK.K sp|P07814|SYEP_HUMAN 1 1586.7285 1.01 127128 5559 2 1586.727548 794.3715 Bifunctional glutamate\proline--tRNA ligase OS=Homo sapiens OX=9606 GN=EPRS1 PE=1 SV=5 6 1544.3 - 284955 - - - -0.5855 - 3.43 0.709 - 1113.7 1 2 0 -0.0009 18 0 0 0 1.05E+07 1.04E+07 - - - 7.3077 1 221125_WJC_METTL3_EV_vs_WT_F09.05562.05562.2 8.32E-09 13/38 K.AEGDSAGTAGTPGGTPAGDK.V "sp|Q92925|SMRD2_HUMAN,tr|B9EGA3|B9EGA3_HUMAN,tr|J3KMX2|J3KMX2_HUMAN" 3 1715.7598 1 127131 5562 2 1715.760886 858.8872 SWI\SNF-related matrix-associated actin-dependent regulator of chromatin subfamily D member 2 OS=Homo sapiens OX=9606 GN=SMARCD2 PE=1 SV=3 4.03 1544.7 - 108307 - - - 0.612 - 2.651 0.645 - 259.3 1 2 0 0.001 20 0 0 0 1.73E+06 1.73E+06 - - - 6.2016 0.9998 221125_WJC_METTL3_EV_vs_WT_F09.05567.05567.3 3.64E-05 14/48 K.IQDK[136.11]EGIPPDQQR[166.11].L "sp|P62979|RS27A_HUMAN,sp|P0CG48|UBC_HUMAN,sp|P0CG48|UBC_HUMAN,sp|P0CG48|UBC_HUMAN,sp|P0CG48|UBC_HUMAN,sp|P0CG48|UBC_HUMAN,sp|P0CG48|UBC_HUMAN,sp|P0CG48|UBC_HUMAN,sp|P0CG48|UBC_HUMAN,sp|P0CG48|UBC_HUMAN,sp|P0CG47|UBB_HUMAN,sp|P0CG47|UBB_HUMAN,sp|P0CG47|UBB_HUMAN,sp|P62987|RL40_HUMAN,tr|F5H388|F5H388_HUMAN,tr|F5H388|F5H388_HUMAN,tr|F5GYU3|F5GYU3_HUMAN,tr|F5GYU3|F5GYU3_HUMAN,tr|B4DV12|B4DV12_HUMAN,tr|B4DV12|B4DV12_HUMAN,tr|J3QSA3|J3QSA3_HUMAN,tr|Q5PY61|Q5PY61_HUMAN,tr|Q5PY61|Q5PY61_HUMAN,tr|Q5PY61|Q5PY61_HUMAN,tr|F5H2Z3|F5H2Z3_HUMAN,tr|F5H2Z3|F5H2Z3_HUMAN,tr|M0R2S1|M0R2S1_HUMAN,tr|J3QS39|J3QS39_HUMAN,tr|J3QTR3|J3QTR3_HUMAN,tr|Q96C32|Q96C32_HUMAN,tr|Q96C32|Q96C32_HUMAN,tr|Q96C32|Q96C32_HUMAN,tr|Q96C32|Q96C32_HUMAN,tr|M0R1V7|M0R1V7_HUMAN,tr|F5H747|F5H747_HUMAN,tr|F5H747|F5H747_HUMAN,tr|F5GXK7|F5GXK7_HUMAN,tr|F5GXK7|F5GXK7_HUMAN,tr|M0R1M6|M0R1M6_HUMAN,tr|F5H6Q2|F5H6Q2_HUMAN,tr|F5H6Q2|F5H6Q2_HUMAN,tr|F5GZ39|F5GZ39_HUMAN,tr|J3QKN0|J3QKN0_HUMAN,tr|J3QKN0|J3QKN0_HUMAN,tr|F5H265|F5H265_HUMAN,tr|F5H265|F5H265_HUMAN,tr|A0A2R8Y422|A0A2R8Y422_HUMAN" 47 1540.7964 0.71 127134 5567 3 1540.797052 514.6061 Ubiquitin-40S ribosomal protein S27a OS=Homo sapiens OX=9606 GN=RPS27A PE=1 SV=2 4.56 1545.3 - 3.25E+06 - - - 0.3972 - 2.538 0.449 - 308.4 1 2 1 0.0006 13 0 0 0 2.95E+07 4.16E+07 - - - 6.071 0.9998 221125_WJC_METTL3_EV_vs_WT_F09.05568.05568.3 3.02E-05 14/48 K.IQDKEGIPPDQQR.L "sp|P62979|RS27A_HUMAN,sp|P0CG48|UBC_HUMAN,sp|P0CG48|UBC_HUMAN,sp|P0CG48|UBC_HUMAN,sp|P0CG48|UBC_HUMAN,sp|P0CG48|UBC_HUMAN,sp|P0CG48|UBC_HUMAN,sp|P0CG48|UBC_HUMAN,sp|P0CG48|UBC_HUMAN,sp|P0CG48|UBC_HUMAN,sp|P0CG47|UBB_HUMAN,sp|P0CG47|UBB_HUMAN,sp|P0CG47|UBB_HUMAN,sp|P62987|RL40_HUMAN,tr|F5H388|F5H388_HUMAN,tr|F5H388|F5H388_HUMAN,tr|F5GYU3|F5GYU3_HUMAN,tr|F5GYU3|F5GYU3_HUMAN,tr|B4DV12|B4DV12_HUMAN,tr|B4DV12|B4DV12_HUMAN,tr|J3QSA3|J3QSA3_HUMAN,tr|Q5PY61|Q5PY61_HUMAN,tr|Q5PY61|Q5PY61_HUMAN,tr|Q5PY61|Q5PY61_HUMAN,tr|F5H2Z3|F5H2Z3_HUMAN,tr|F5H2Z3|F5H2Z3_HUMAN,tr|M0R2S1|M0R2S1_HUMAN,tr|J3QS39|J3QS39_HUMAN,tr|J3QTR3|J3QTR3_HUMAN,tr|Q96C32|Q96C32_HUMAN,tr|Q96C32|Q96C32_HUMAN,tr|Q96C32|Q96C32_HUMAN,tr|Q96C32|Q96C32_HUMAN,tr|M0R1V7|M0R1V7_HUMAN,tr|F5H747|F5H747_HUMAN,tr|F5H747|F5H747_HUMAN,tr|F5GXK7|F5GXK7_HUMAN,tr|F5GXK7|F5GXK7_HUMAN,tr|M0R1M6|M0R1M6_HUMAN,tr|F5H6Q2|F5H6Q2_HUMAN,tr|F5H6Q2|F5H6Q2_HUMAN,tr|F5GZ39|F5GZ39_HUMAN,tr|J3QKN0|J3QKN0_HUMAN,tr|J3QKN0|J3QKN0_HUMAN,tr|F5H265|F5H265_HUMAN,tr|F5H265|F5H265_HUMAN,tr|A0A2R8Y422|A0A2R8Y422_HUMAN" 47 1522.774 0.75 127135 5568 3 1522.774932 508.5986 Ubiquitin-40S ribosomal protein S27a OS=Homo sapiens OX=9606 GN=RPS27A PE=1 SV=2 4.56 1545.3 - 2.42E+06 - - - 0.6317 - 2.675 0.431 - 323 1 2 1 0.001 13 0 0 0 8.44E+07 1.13E+08 - - - 6.0127 0.9995 221125_WJC_METTL3_EV_vs_WT_F09.05570.05570.3 0.0027 Oct-40 K.QNQHEELQNVR[166.11].K "sp|Q8NHH9|ATLA2_HUMAN,tr|B5MCN0|B5MCN0_HUMAN,tr|H7C3A2|H7C3A2_HUMAN,tr|C9JQQ5|C9JQQ5_HUMAN" 4 1403.6781 5.12 127137 5570 3 1403.676688 468.9 Atlastin-2 OS=Homo sapiens OX=9606 GN=ATL2 PE=1 SV=2 5.4 1545.4 - 1.64E+06 - - - -1.0123 - 1.944 0.304 - 240.8 1 2 0 -0.0014 11 0 0 0 3.47E+07 6.76E+06 - - - 3.8173 1 221125_WJC_METTL3_EV_vs_WT_F09.05572.05572.2 7.94E-13 21/34 K.NQGGGLSSSGAGEGQGPK[136.11].K sp|P07814|SYEP_HUMAN 1 1594.7427 1.01 127139 5572 2 1594.742727 798.3786 Bifunctional glutamate\proline--tRNA ligase OS=Homo sapiens OX=9606 GN=EPRS1 PE=1 SV=5 6 1545.6 - 1.43E+06 - - - 0.0314 - 3.671 0.735 - 1437.5 1 2 0 0.0001 18 0 0 0 1.05E+07 1.04E+07 - - - 7.6669 1 221125_WJC_METTL3_EV_vs_WT_F09.05576.05576.3 1.06E-05 Dec-52 K.HMAAASAEC[160.03]QNYAK.E "sp|Q9P2E9|RRBP1_HUMAN,tr|A0A087WU26|A0A087WU26_HUMAN,tr|A0A087WVV2|A0A087WVV2_HUMAN,tr|F8W7S5|F8W7S5_HUMAN" 4 1550.6606 0.9 127143 5576 3 1550.660876 517.8941 Ribosome-binding protein 1 OS=Homo sapiens OX=9606 GN=RRBP1 PE=1 SV=5 6.74 1545.9 - 756045 - - - 0.1799 - 2.239 0.538 - 97.3 1 2 0 0.0003 14 0 0 0 3.35E+06 3.72E+06 - - - 6.6801 0.9967 221125_WJC_METTL3_EV_vs_WT_F09.05577.05577.2 0.00991 18-Oct K.VQVEYK[136.11]GETK[136.11].T "sp|P54652|HSP72_HUMAN,sp|P11142|HSP7C_HUMAN,tr|E9PQQ4|E9PQQ4_HUMAN,tr|E9PKE3|E9PKE3_HUMAN,tr|E9PN89|E9PN89_HUMAN,tr|E9PLF4|E9PLF4_HUMAN,tr|E9PK54|E9PK54_HUMAN,tr|E9PN25|E9PN25_HUMAN,tr|E9PPY6|E9PPY6_HUMAN,tr|E9PQK7|E9PQK7_HUMAN" 10 1195.642 0.45 127144 5577 2 1195.642812 598.8283 Heat shock-related 70 kDa protein 2 OS=Homo sapiens OX=9606 GN=HSPA2 PE=1 SV=1 6.11 1546 - 456235 - - - 0.7184 - 1.929 0.395 - 439.7 1 2 1 0.0009 10 0 0 0 2.30E+06 5.12E+06 - - - 3.7921 1 221125_WJC_METTL3_EV_vs_WT_F09.05580.05580.2 9.30E-12 15/38 K.AEGDSAGTAGTPGGTPAGDK[136.11].V "sp|Q92925|SMRD2_HUMAN,tr|B9EGA3|B9EGA3_HUMAN,tr|J3KMX2|J3KMX2_HUMAN" 3 1723.774 1 127147 5580 2 1723.774484 862.8943 SWI\SNF-related matrix-associated actin-dependent regulator of chromatin subfamily D member 2 OS=Homo sapiens OX=9606 GN=SMARCD2 PE=1 SV=3 4.03 1546.4 - 298423 - - - 0.2599 - 3.156 0.752 - 449 1 2 0 0.0004 20 0 0 0 1.73E+06 1.73E+06 - - - 7.4208 1 221125_WJC_METTL3_EV_vs_WT_F09.05582.05582.2 0.000193 14/24 K.FQR[166.11]PGDPQSAQDK[136.11].A "sp|Q15637|SF01_HUMAN,tr|H7C561|H7C561_HUMAN,tr|A0A7P0T9U7|A0A7P0T9U7_HUMAN" 3 1490.7233 1.7 127149 5582 2 1490.722801 746.3689 Splicing factor 1 OS=Homo sapiens OX=9606 GN=SF1 PE=1 SV=4 5.96 1546.7 - 123942 - - - -0.318 - 3.089 0.562 - 491.3 1 2 0 -0.0005 13 0 0 0 3.72E+07 2.20E+07 - - - 6.0864 0.9999 221125_WJC_METTL3_EV_vs_WT_F09.05584.05584.2 0.00228 13/16 R.K[136.11]ADIDLTK[136.11]R[166.11].A sp|P62269|RS18_HUMAN 1 1084.6451 1 127150 5584 2 1084.645256 543.3298 40S ribosomal protein S18 OS=Homo sapiens OX=9606 GN=RPS18 PE=1 SV=3 8.59 1546.9 - 3.39E+06 - - - 0.1641 - 2.449 0.425 - 673 1 2 0 0.0002 9 0 0 0 1.52E+07 1.51E+07 - - - 4.7712 0.9999 221125_WJC_METTL3_EV_vs_WT_F09.05586.05586.3 1.34E-05 Dec-44 R.RYPSSISSSPQK.D "sp|Q14157|UBP2L_HUMAN,tr|F8W726|F8W726_HUMAN" 2 1335.6783 2.16 127151 5586 3 1335.678523 446.2334 Ubiquitin-associated protein 2-like OS=Homo sapiens OX=9606 GN=UBAP2L PE=1 SV=2 9.99 1547.2 - 3.42E+06 - - - 0.1827 - 2.146 0.458 - 222.7 1 2 0 0.0002 12 0 0 0 2.81E+08 1.30E+08 - - - 5.7628 1 221125_WJC_METTL3_EV_vs_WT_F09.05587.05587.3 3.65E-06 17/44 K.DSYVGDEAQSK[136.11]R[166.11].G "sp|P63261|ACTG_HUMAN,sp|P68133|ACTS_HUMAN,sp|P62736|ACTA_HUMAN,sp|P68032|ACTC_HUMAN,sp|P60709|ACTB_HUMAN,sp|P63267|ACTH_HUMAN,tr|A0A804GS07|A0A804GS07_HUMAN,tr|I3L3I0|I3L3I0_HUMAN,tr|G5E9R0|G5E9R0_HUMAN,tr|E7EVS6|E7EVS6_HUMAN,tr|A0A6Q8PFE4|A0A6Q8PFE4_HUMAN,tr|B8ZZJ2|B8ZZJ2_HUMAN,tr|J3KT65|J3KT65_HUMAN,tr|I3L3R2|I3L3R2_HUMAN,tr|K7EM38|K7EM38_HUMAN,tr|F6QUT6|F6QUT6_HUMAN,tr|C9JTX5|C9JTX5_HUMAN,tr|A0A6Q8PH58|A0A6Q8PH58_HUMAN,tr|F6UVQ4|F6UVQ4_HUMAN,tr|F8WB63|F8WB63_HUMAN,tr|I3L1U9|I3L1U9_HUMAN,tr|A0A804HKV3|A0A804HKV3_HUMAN,tr|A0A2R8Y793|A0A2R8Y793_HUMAN,tr|I3L4N8|I3L4N8_HUMAN,tr|C9JUM1|C9JUM1_HUMAN,tr|C9JZR7|C9JZR7_HUMAN,tr|C9JFL5|C9JFL5_HUMAN,tr|A0A2R8YGF8|A0A2R8YGF8_HUMAN,tr|A6NL76|A6NL76_HUMAN" 29 1371.6385 0.83 127152 5587 3 1371.637842 458.2201 "Actin, cytoplasmic 2 OS=Homo sapiens OX=9606 GN=ACTG1 PE=1 SV=1" 4.56 1547.2 - 3.89E+06 - - - -0.5111 - 2.816 0.577 - 328.1 1 2 0 -0.0007 12 0 0 0 3.04E+08 3.68E+08 - - - 7.8425 0.9987 221125_WJC_METTL3_EV_vs_WT_F09.05589.05589.3 0.0311 15/44 K.DSYVGDEAQSKR.G "sp|P63261|ACTG_HUMAN,sp|P68133|ACTS_HUMAN,sp|P62736|ACTA_HUMAN,sp|P68032|ACTC_HUMAN,sp|P60709|ACTB_HUMAN,sp|P63267|ACTH_HUMAN,tr|A0A804GS07|A0A804GS07_HUMAN,tr|I3L3I0|I3L3I0_HUMAN,tr|G5E9R0|G5E9R0_HUMAN,tr|E7EVS6|E7EVS6_HUMAN,tr|A0A6Q8PFE4|A0A6Q8PFE4_HUMAN,tr|B8ZZJ2|B8ZZJ2_HUMAN,tr|J3KT65|J3KT65_HUMAN,tr|I3L3R2|I3L3R2_HUMAN,tr|K7EM38|K7EM38_HUMAN,tr|F6QUT6|F6QUT6_HUMAN,tr|C9JTX5|C9JTX5_HUMAN,tr|A0A6Q8PH58|A0A6Q8PH58_HUMAN,tr|F6UVQ4|F6UVQ4_HUMAN,tr|F8WB63|F8WB63_HUMAN,tr|I3L1U9|I3L1U9_HUMAN,tr|A0A804HKV3|A0A804HKV3_HUMAN,tr|A0A2R8Y793|A0A2R8Y793_HUMAN,tr|I3L4N8|I3L4N8_HUMAN,tr|C9JUM1|C9JUM1_HUMAN,tr|C9JZR7|C9JZR7_HUMAN,tr|C9JFL5|C9JFL5_HUMAN,tr|A0A2R8YGF8|A0A2R8YGF8_HUMAN,tr|A6NL76|A6NL76_HUMAN" 29 1353.6161 0.83 127154 5589 3 1353.607758 452.2126 "Actin, cytoplasmic 2 OS=Homo sapiens OX=9606 GN=ACTG1 PE=1 SV=1" 4.56 1547.3 - 1.87E+06 - - - -6.1428 - 2.652 0.448 - 302.6 1 2 0 -0.0083 12 0 0 0 3.04E+08 3.68E+08 - - - 6.2359 1 221125_WJC_METTL3_EV_vs_WT_F09.05590.05590.2 2.64E-07 22-Dec W.PDATYGTGSASR.A "sp|Q9Y2W1|TR150_HUMAN,tr|A0A3B3ITZ9|A0A3B3ITZ9_HUMAN" 2 1181.5313 2.46 127155 5590 2 1181.529938 591.7729 Thyroid hormone receptor-associated protein 3 OS=Homo sapiens OX=9606 GN=THRAP3 PE=1 SV=2 6.26 1547.4 - 1.27E+06 - - - -1.1358 - 2.394 0.641 - 556.8 1 1 0 -0.0013 12 0 0 0 6.22E+06 2.53E+06 - - - 6.0719 0.9999 221125_WJC_METTL3_EV_vs_WT_F09.05591.05591.2 1.68E-05 15/22 R.RYPSSISSSPQK.D "sp|Q14157|UBP2L_HUMAN,tr|F8W726|F8W726_HUMAN" 2 1335.6783 2.32 127156 5591 2 1335.677919 668.8464 Ubiquitin-associated protein 2-like OS=Homo sapiens OX=9606 GN=UBAP2L PE=1 SV=2 9.99 1547.6 - 949076 - - - -0.2695 - 2.638 0.484 - 510.7 1 2 0 -0.0004 12 0 0 0 1.14E+08 4.90E+07 - - - 5.168 0.9988 221125_WJC_METTL3_EV_vs_WT_F09.05592.05592.2 0.00444 18/22 R.SKEEAEALYHSK.Y sp|P35908|K22E_HUMAN 1 1390.6729 54.79 127157 5592 2 1390.6714 696.3437 "Keratin, type II cytoskeletal 2 epidermal OS=Homo sapiens OX=9606 GN=KRT2 PE=1 SV=2" 5.47 1547.7 - 824517 - - - -1.0491 - 3.15 0.477 - 966.9 1 2 1 -0.0015 12 0 0 0 1.26E+07 2.29E+05 - - - 5.5827 1 221125_WJC_METTL3_EV_vs_WT_F09.05597.05597.2 2.07E-10 15/20 L.HDDEVTVTEDK.L sp|P05386|RLA1_HUMAN 1 1286.5626 1.35 127162 5597 2 1286.560437 644.2886 60S acidic ribosomal protein P1 OS=Homo sapiens OX=9606 GN=RPLP1 PE=1 SV=1 4.1 1548.2 - 469773 - - - -1.7123 - 3.189 0.571 - 699.2 1 1 0 -0.0022 11 0 0 0 2.96E+06 2.19E+06 - - - 6.395 0.9999 221125_WJC_METTL3_EV_vs_WT_F09.05598.05598.2 4.36E-06 14/22 K.DSYVGDEAQSK[136.11]R[166.11].G "sp|P63261|ACTG_HUMAN,sp|P68133|ACTS_HUMAN,sp|P62736|ACTA_HUMAN,sp|P68032|ACTC_HUMAN,sp|P60709|ACTB_HUMAN,sp|P63267|ACTH_HUMAN,tr|A0A804GS07|A0A804GS07_HUMAN,tr|I3L3I0|I3L3I0_HUMAN,tr|G5E9R0|G5E9R0_HUMAN,tr|E7EVS6|E7EVS6_HUMAN,tr|A0A6Q8PFE4|A0A6Q8PFE4_HUMAN,tr|B8ZZJ2|B8ZZJ2_HUMAN,tr|J3KT65|J3KT65_HUMAN,tr|I3L3R2|I3L3R2_HUMAN,tr|K7EM38|K7EM38_HUMAN,tr|F6QUT6|F6QUT6_HUMAN,tr|C9JTX5|C9JTX5_HUMAN,tr|A0A6Q8PH58|A0A6Q8PH58_HUMAN,tr|F6UVQ4|F6UVQ4_HUMAN,tr|F8WB63|F8WB63_HUMAN,tr|I3L1U9|I3L1U9_HUMAN,tr|A0A804HKV3|A0A804HKV3_HUMAN,tr|A0A2R8Y793|A0A2R8Y793_HUMAN,tr|I3L4N8|I3L4N8_HUMAN,tr|C9JUM1|C9JUM1_HUMAN,tr|C9JZR7|C9JZR7_HUMAN,tr|C9JFL5|C9JFL5_HUMAN,tr|A0A2R8YGF8|A0A2R8YGF8_HUMAN,tr|A6NL76|A6NL76_HUMAN" 29 1371.6385 0.87 127163 5598 2 1371.638862 686.8265 "Actin, cytoplasmic 2 OS=Homo sapiens OX=9606 GN=ACTG1 PE=1 SV=1" 4.56 1548.3 - 329441 - - - 0.2326 - 2.139 0.609 - 491 1 2 0 0.0003 12 0 0 0 4.91E+07 5.68E+07 - - - 5.5396 0.9999 221125_WJC_METTL3_EV_vs_WT_F09.05602.05602.3 4.65E-06 17/44 R.SKEEAEALYHSK.Y sp|P35908|K22E_HUMAN 1 1390.6729 95.12 127166 5602 3 1390.672265 464.5649 "Keratin, type II cytoskeletal 2 epidermal OS=Homo sapiens OX=9606 GN=KRT2 PE=1 SV=2" 5.47 1548.8 - 9.55E+07 - - - -0.4271 - 3.205 0.498 - 458.3 1 2 1 -0.0006 12 0 0 0 3.25E+08 3.41E+06 - - - 7.3205 0.9999 221125_WJC_METTL3_EV_vs_WT_F09.05604.05604.3 4.38E-05 14/48 K.FQRPGDPQSAQDK.A "sp|Q15637|SF01_HUMAN,tr|H7C561|H7C561_HUMAN,tr|A0A7P0T9U7|A0A7P0T9U7_HUMAN" 3 1472.7008 1.21 127167 5604 3 1472.699185 491.9075 Splicing factor 1 OS=Homo sapiens OX=9606 GN=SF1 PE=1 SV=4 5.96 1549 - 1.40E+07 - - - -1.1 - 2.42 0.394 - 240 1 2 0 -0.0016 13 0 0 0 3.94E+08 3.25E+08 - - - 5.3284 0.9975 221125_WJC_METTL3_EV_vs_WT_F09.05605.05605.3 0.211 Sep-36 K.VSELK[136.11]EELK[136.11]K[136.11].R "sp|Q00839|HNRPU_HUMAN,tr|A0A1W2PPS1|A0A1W2PPS1_HUMAN,tr|A0A1X7SBS1|A0A1X7SBS1_HUMAN" 3 1225.7344 1.02 127168 5605 3 1225.731981 409.5854 Heterogeneous nuclear ribonucleoprotein U OS=Homo sapiens OX=9606 GN=HNRNPU PE=1 SV=6 6.2 1549 - 8.50E+06 - - - -1.9768 - 1.854 0.348 - 89.5 1 2 1 -0.0024 10 0 0 0 5.41E+08 5.32E+08 - - - 4.2221 0.9935 221125_WJC_METTL3_EV_vs_WT_F09.05611.05611.2 2.50E-07 18-Dec S.YVGDEAQSK[136.11]R[166.11].G "sp|P63261|ACTG_HUMAN,sp|P68133|ACTS_HUMAN,sp|P62736|ACTA_HUMAN,sp|P68032|ACTC_HUMAN,sp|Q562R1|ACTBL_HUMAN,sp|P60709|ACTB_HUMAN,sp|P63267|ACTH_HUMAN,tr|A0A804GS07|A0A804GS07_HUMAN,tr|I3L3I0|I3L3I0_HUMAN,tr|G5E9R0|G5E9R0_HUMAN,tr|E7EVS6|E7EVS6_HUMAN,tr|A0A6Q8PFE4|A0A6Q8PFE4_HUMAN,tr|B8ZZJ2|B8ZZJ2_HUMAN,tr|J3KT65|J3KT65_HUMAN,tr|I3L3R2|I3L3R2_HUMAN,tr|K7EM38|K7EM38_HUMAN,tr|F6QUT6|F6QUT6_HUMAN,tr|C9JTX5|C9JTX5_HUMAN,tr|A0A6Q8PH58|A0A6Q8PH58_HUMAN,tr|F6UVQ4|F6UVQ4_HUMAN,tr|F8WB63|F8WB63_HUMAN,tr|I3L1U9|I3L1U9_HUMAN,tr|A0A804HKV3|A0A804HKV3_HUMAN,tr|A0A2R8Y793|A0A2R8Y793_HUMAN,tr|I3L4N8|I3L4N8_HUMAN,tr|C9JUM1|C9JUM1_HUMAN,tr|C9JZR7|C9JZR7_HUMAN,tr|C9JFL5|C9JFL5_HUMAN,tr|A0A2R8YGF8|A0A2R8YGF8_HUMAN,tr|A6NL76|A6NL76_HUMAN" 30 1169.5796 1.09 127174 5611 2 1169.578284 585.7971 "Actin, cytoplasmic 2 OS=Homo sapiens OX=9606 GN=ACTG1 PE=1 SV=1" 6.07 1549.5 - 1.26E+06 - - - -1.1004 - 2.04 0.61 - 414.9 1 1 0 -0.0013 10 0 0 0 9.07E+06 8.31E+06 - - - 5.5361 1 221125_WJC_METTL3_EV_vs_WT_F09.05615.05615.2 1.51E-06 20/20 R.RLPDAHSDYAR.Y sp|Q96PK6|RBM14_HUMAN 1 1299.632 1.74 127178 5615 2 1299.630458 650.8233 RNA-binding protein 14 OS=Homo sapiens OX=9606 GN=RBM14 PE=1 SV=2 6.75 1550 - 1.06E+06 - - - -1.1842 - 3.066 0.558 - 894.2 1 2 0 -0.0015 11 0 0 0 2.52E+07 1.45E+07 - - - 6.1928 0.9871 221125_WJC_METTL3_EV_vs_WT_F09.05616.05616.2 8.50E-06 18-Oct S.YVGDEAQSKR.G "sp|P63261|ACTG_HUMAN,sp|P68133|ACTS_HUMAN,sp|P62736|ACTA_HUMAN,sp|P68032|ACTC_HUMAN,sp|Q562R1|ACTBL_HUMAN,sp|P60709|ACTB_HUMAN,sp|P63267|ACTH_HUMAN,tr|A0A804GS07|A0A804GS07_HUMAN,tr|I3L3I0|I3L3I0_HUMAN,tr|G5E9R0|G5E9R0_HUMAN,tr|E7EVS6|E7EVS6_HUMAN,tr|A0A6Q8PFE4|A0A6Q8PFE4_HUMAN,tr|B8ZZJ2|B8ZZJ2_HUMAN,tr|J3KT65|J3KT65_HUMAN,tr|I3L3R2|I3L3R2_HUMAN,tr|K7EM38|K7EM38_HUMAN,tr|F6QUT6|F6QUT6_HUMAN,tr|C9JTX5|C9JTX5_HUMAN,tr|A0A6Q8PH58|A0A6Q8PH58_HUMAN,tr|F6UVQ4|F6UVQ4_HUMAN,tr|F8WB63|F8WB63_HUMAN,tr|I3L1U9|I3L1U9_HUMAN,tr|A0A804HKV3|A0A804HKV3_HUMAN,tr|A0A2R8Y793|A0A2R8Y793_HUMAN,tr|I3L4N8|I3L4N8_HUMAN,tr|C9JUM1|C9JUM1_HUMAN,tr|C9JZR7|C9JZR7_HUMAN,tr|C9JFL5|C9JFL5_HUMAN,tr|A0A2R8YGF8|A0A2R8YGF8_HUMAN,tr|A6NL76|A6NL76_HUMAN" 30 1151.5571 1.09 127179 5616 2 1151.55467 576.7858 "Actin, cytoplasmic 2 OS=Homo sapiens OX=9606 GN=ACTG1 PE=1 SV=1" 6.07 1550.2 - 1.00E+06 - - - -2.1111 - 1.835 0.63 - 277.4 1 1 0 -0.0024 10 0 0 0 9.07E+06 8.31E+06 - - - 5.3879 0.9998 221125_WJC_METTL3_EV_vs_WT_F09.05618.05618.2 8.70E-05 24-Sep K.WTSQHSNTQTLGK[136.11].- sp|Q6PKG0|LARP1_HUMAN 1 1494.7307 0.08 127181 5618 2 1494.729745 748.3726 La-related protein 1 OS=Homo sapiens OX=9606 GN=LARP1 PE=1 SV=2 8.76 1550.4 - 507801 - - - -0.6088 - 2.008 0.418 - 100.1 1 2 0 -0.0009 13 0 0 0 2.67E+05 3.15E+06 - - - 3.9173 0.999 221125_WJC_METTL3_EV_vs_WT_F09.05623.05623.2 1.15E-05 13/24 K.IQDK[136.11]EGIPPDQQR[166.11].L "sp|P62979|RS27A_HUMAN,sp|P0CG48|UBC_HUMAN,sp|P0CG48|UBC_HUMAN,sp|P0CG48|UBC_HUMAN,sp|P0CG48|UBC_HUMAN,sp|P0CG48|UBC_HUMAN,sp|P0CG48|UBC_HUMAN,sp|P0CG48|UBC_HUMAN,sp|P0CG48|UBC_HUMAN,sp|P0CG48|UBC_HUMAN,sp|P0CG47|UBB_HUMAN,sp|P0CG47|UBB_HUMAN,sp|P0CG47|UBB_HUMAN,sp|P62987|RL40_HUMAN,tr|F5H388|F5H388_HUMAN,tr|F5H388|F5H388_HUMAN,tr|F5GYU3|F5GYU3_HUMAN,tr|F5GYU3|F5GYU3_HUMAN,tr|B4DV12|B4DV12_HUMAN,tr|B4DV12|B4DV12_HUMAN,tr|J3QSA3|J3QSA3_HUMAN,tr|Q5PY61|Q5PY61_HUMAN,tr|Q5PY61|Q5PY61_HUMAN,tr|Q5PY61|Q5PY61_HUMAN,tr|F5H2Z3|F5H2Z3_HUMAN,tr|F5H2Z3|F5H2Z3_HUMAN,tr|M0R2S1|M0R2S1_HUMAN,tr|J3QS39|J3QS39_HUMAN,tr|J3QTR3|J3QTR3_HUMAN,tr|Q96C32|Q96C32_HUMAN,tr|Q96C32|Q96C32_HUMAN,tr|Q96C32|Q96C32_HUMAN,tr|Q96C32|Q96C32_HUMAN,tr|M0R1V7|M0R1V7_HUMAN,tr|F5H747|F5H747_HUMAN,tr|F5H747|F5H747_HUMAN,tr|F5GXK7|F5GXK7_HUMAN,tr|F5GXK7|F5GXK7_HUMAN,tr|M0R1M6|M0R1M6_HUMAN,tr|F5H6Q2|F5H6Q2_HUMAN,tr|F5H6Q2|F5H6Q2_HUMAN,tr|F5GZ39|F5GZ39_HUMAN,tr|J3QKN0|J3QKN0_HUMAN,tr|J3QKN0|J3QKN0_HUMAN,tr|F5H265|F5H265_HUMAN,tr|F5H265|F5H265_HUMAN,tr|A0A2R8Y422|A0A2R8Y422_HUMAN" 47 1540.7964 0.81 127186 5623 2 1540.795119 771.4055 Ubiquitin-40S ribosomal protein S27a OS=Homo sapiens OX=9606 GN=RPS27A PE=1 SV=2 4.56 1551 - 298213 - - - -0.8573 - 2.769 0.549 - 415.6 1 2 1 -0.0013 13 0 0 0 1.14E+06 1.41E+06 - - - 5.7095 0.9998 221125_WJC_METTL3_EV_vs_WT_F09.05625.05625.2 8.00E-05 22-Nov K.DSYVGDEAQSKR.G "sp|P63261|ACTG_HUMAN,sp|P68133|ACTS_HUMAN,sp|P62736|ACTA_HUMAN,sp|P68032|ACTC_HUMAN,sp|P60709|ACTB_HUMAN,sp|P63267|ACTH_HUMAN,tr|A0A804GS07|A0A804GS07_HUMAN,tr|I3L3I0|I3L3I0_HUMAN,tr|G5E9R0|G5E9R0_HUMAN,tr|E7EVS6|E7EVS6_HUMAN,tr|A0A6Q8PFE4|A0A6Q8PFE4_HUMAN,tr|B8ZZJ2|B8ZZJ2_HUMAN,tr|J3KT65|J3KT65_HUMAN,tr|I3L3R2|I3L3R2_HUMAN,tr|K7EM38|K7EM38_HUMAN,tr|F6QUT6|F6QUT6_HUMAN,tr|C9JTX5|C9JTX5_HUMAN,tr|A0A6Q8PH58|A0A6Q8PH58_HUMAN,tr|F6UVQ4|F6UVQ4_HUMAN,tr|F8WB63|F8WB63_HUMAN,tr|I3L1U9|I3L1U9_HUMAN,tr|A0A804HKV3|A0A804HKV3_HUMAN,tr|A0A2R8Y793|A0A2R8Y793_HUMAN,tr|I3L4N8|I3L4N8_HUMAN,tr|C9JUM1|C9JUM1_HUMAN,tr|C9JZR7|C9JZR7_HUMAN,tr|C9JFL5|C9JFL5_HUMAN,tr|A0A2R8YGF8|A0A2R8YGF8_HUMAN,tr|A6NL76|A6NL76_HUMAN" 29 1353.6161 0.87 127187 5625 2 1353.613984 677.8153 "Actin, cytoplasmic 2 OS=Homo sapiens OX=9606 GN=ACTG1 PE=1 SV=1" 4.56 1551.2 - 1.71E+07 - - - -1.5433 - 1.746 0.55 - 258.5 1 2 0 -0.0021 12 0 0 0 4.91E+07 5.68E+07 - - - 4.5691 0.9456 221125_WJC_METTL3_EV_vs_WT_F09.05627.05627.2 4.71E-05 14-Oct P.DAHSDYAR.Y sp|Q96PK6|RBM14_HUMAN 1 933.3941 2.55 127189 5627 2 933.391923 467.7043 RNA-binding protein 14 OS=Homo sapiens OX=9606 GN=RBM14 PE=1 SV=2 5.21 1551.4 - 1.55E+07 - - - -2.2874 - 1.755 0.356 - 335.7 1 1 0 -0.0021 8 0 0 0 6.35E+07 2.49E+07 - - - 3.3661 0.9982 221125_WJC_METTL3_EV_vs_WT_F09.05628.05628.2 2.58E-05 13/18 K.VSELK[136.11]EELK[136.11]K[136.11].R "sp|Q00839|HNRPU_HUMAN,tr|A0A1W2PPS1|A0A1W2PPS1_HUMAN,tr|A0A1X7SBS1|A0A1X7SBS1_HUMAN" 3 1225.7344 1.12 127190 5628 2 1225.732162 613.8745 Heterogeneous nuclear ribonucleoprotein U OS=Homo sapiens OX=9606 GN=HNRNPU PE=1 SV=6 6.2 1551.5 - 9.30E+06 - - - -1.8291 - 2.533 0.544 - 525.3 1 2 1 -0.0022 10 0 0 0 4.92E+07 4.40E+07 - - - 5.6525 0.9972 221125_WJC_METTL3_EV_vs_WT_F09.05629.05629.2 0.000696 16/18 K.VSELKEELKK.R "sp|Q00839|HNRPU_HUMAN,tr|A0A1W2PPS1|A0A1W2PPS1_HUMAN,tr|A0A1X7SBS1|A0A1X7SBS1_HUMAN" 3 1201.6918 1.12 127191 5629 2 1201.689257 601.8532 Heterogeneous nuclear ribonucleoprotein U OS=Homo sapiens OX=9606 GN=HNRNPU PE=1 SV=6 6.2 1551.5 - 8.72E+06 - - - -2.1195 - 2.952 0.412 - 948.9 1 2 1 -0.0025 10 0 0 0 4.92E+07 4.40E+07 - - - 5.1048 0.816 221125_WJC_METTL3_EV_vs_WT_F09.05631.05631.2 0.195 13/16 V.SELKEELKK.R "sp|Q00839|HNRPU_HUMAN,tr|A0A1W2PPS1|A0A1W2PPS1_HUMAN,tr|A0A1X7SBS1|A0A1X7SBS1_HUMAN" 3 1102.6234 1.15 127193 5631 2 1102.621403 552.319 Heterogeneous nuclear ribonucleoprotein U OS=Homo sapiens OX=9606 GN=HNRNPU PE=1 SV=6 5.95 1551.6 - 6.94E+06 - - - -1.8021 - 2.537 0.34 - 605.7 1 1 1 -0.002 9 0 0 0 4.16E+07 3.63E+07 - - - 4.245 0.772 221125_WJC_METTL3_EV_vs_WT_F09.05632.05632.2 0.126 16-Dec V.SELK[136.11]EELK[136.11]K[136.11].R "sp|Q00839|HNRPU_HUMAN,tr|A0A1W2PPS1|A0A1W2PPS1_HUMAN,tr|A0A1X7SBS1|A0A1X7SBS1_HUMAN" 3 1126.666 1.15 127194 5632 2 1126.663942 564.3403 Heterogeneous nuclear ribonucleoprotein U OS=Homo sapiens OX=9606 GN=HNRNPU PE=1 SV=6 5.95 1551.6 - 6.72E+06 - - - -1.8178 - 2.221 0.345 - 443.3 1 1 1 -0.002 9 0 0 0 4.16E+07 3.63E+07 - - - 3.8971 0.9505 221125_WJC_METTL3_EV_vs_WT_F09.05633.05633.2 0.000104 14-Sep P.DAHSDYAR[166.11].Y sp|Q96PK6|RBM14_HUMAN 1 943.4023 2.55 127195 5633 2 943.402143 472.7084 RNA-binding protein 14 OS=Homo sapiens OX=9606 GN=RBM14 PE=1 SV=2 5.21 1551.7 - 6.42E+06 - - - -0.1961 - 1.654 0.262 - 253.2 1 1 0 -0.0002 8 0 0 0 6.35E+07 2.49E+07 - - - 2.4937 1 221125_WJC_METTL3_EV_vs_WT_F09.05636.05636.2 1.35E-07 15/20 R.R[166.11]LPDAHSDYAR[166.11].Y sp|Q96PK6|RBM14_HUMAN 1 1319.6485 1.74 127198 5636 2 1319.645949 660.8315 RNA-binding protein 14 OS=Homo sapiens OX=9606 GN=RBM14 PE=1 SV=2 6.75 1551.8 - 3.36E+06 - - - -1.9611 - 2.823 0.532 - 380 1 2 0 -0.0026 11 0 0 0 2.52E+07 1.45E+07 - - - 5.777 1 221125_WJC_METTL3_EV_vs_WT_F09.05637.05637.2 6.20E-07 14/28 K.GGSISGGGYGSGGGK.H sp|P35908|K22E_HUMAN 1 1196.5422 999 127199 5637 2 1196.54001 599.2784 "Keratin, type II cytoskeletal 2 epidermal OS=Homo sapiens OX=9606 GN=KRT2 PE=1 SV=2" 8.59 1551.9 - 2.93E+06 - - - -1.8127 - 2.51 0.655 - 527.9 1 2 0 -0.0022 15 0 0 0 1.36E+07 0.00E+00 - - - 6.1407 1 221125_WJC_METTL3_EV_vs_WT_F09.05640.05640.3 1.06E-07 Nov-44 R.GGSGSHNWGTVK[136.11].D sp|Q8NC51|PAIRB_HUMAN 1 1193.5669 0.84 127202 5640 3 1193.56598 398.8629 Plasminogen activator inhibitor 1 RNA-binding protein OS=Homo sapiens OX=9606 GN=SERBP1 PE=1 SV=2 8.76 1552.1 - 2.09E+06 - - - -0.7574 - 2.447 0.572 - 187.3 1 2 0 -0.0009 12 0 0 0 1.10E+07 1.31E+07 - - - 7.3974 0.9974 221125_WJC_METTL3_EV_vs_WT_F09.05643.05643.3 0.00818 Dec-36 K.VSELKEELKK.R "sp|Q00839|HNRPU_HUMAN,tr|A0A1W2PPS1|A0A1W2PPS1_HUMAN,tr|A0A1X7SBS1|A0A1X7SBS1_HUMAN" 3 1201.6918 1.02 127204 5643 3 1201.68933 401.5712 Heterogeneous nuclear ribonucleoprotein U OS=Homo sapiens OX=9606 GN=HNRNPU PE=1 SV=6 6.2 1552.4 - 1.03E+08 - - - -2.0588 - 2.259 0.296 - 193.8 1 2 1 -0.0025 10 0 0 0 5.41E+08 5.32E+08 - - - 4.2194 1 221125_WJC_METTL3_EV_vs_WT_F09.05644.05644.3 0.000323 15/48 K.FQR[166.11]PGDPQSAQDK[136.11].A "sp|Q15637|SF01_HUMAN,tr|H7C561|H7C561_HUMAN,tr|A0A7P0T9U7|A0A7P0T9U7_HUMAN" 3 1490.7233 1.21 127205 5644 3 1490.720901 497.915 Splicing factor 1 OS=Homo sapiens OX=9606 GN=SF1 PE=1 SV=4 5.96 1552.4 - 2.77E+07 - - - -1.5925 - 2.779 0.466 - 261.6 1 2 0 -0.0024 13 0 0 0 3.93E+08 3.25E+08 - - - 6.506 0.9977 221125_WJC_METTL3_EV_vs_WT_F09.05645.05645.3 0.0643 Dec-36 K.VSELK[136.11]EELKK[136.11].R "sp|Q00839|HNRPU_HUMAN,tr|A0A1W2PPS1|A0A1W2PPS1_HUMAN,tr|A0A1X7SBS1|A0A1X7SBS1_HUMAN" 3 1217.7202 - 127206 5645 3 1217.717883 406.914 Heterogeneous nuclear ribonucleoprotein U OS=Homo sapiens OX=9606 GN=HNRNPU PE=1 SV=6 6.2 1552.5 - 3.63E+06 - - - -1.906 - 2.231 0.3 - 187.2 1 2 1 -0.0023 10 0 0 0 - - - - - 4.2276 1 221125_WJC_METTL3_EV_vs_WT_F09.05649.05649.3 1.90E-05 Dec-52 R.AAHASADLPEASSK[136.11].K "sp|Q5JSZ5|PRC2B_HUMAN,tr|A0A804HKC3|A0A804HKC3_HUMAN,tr|A0A804HJR4|A0A804HJR4_HUMAN" 3 1361.6667 1.36 127208 5649 3 1361.664051 454.8962 Protein PRRC2B OS=Homo sapiens OX=9606 GN=PRRC2B PE=1 SV=2 5.32 1553 - 8.40E+06 - - - -1.9146 - 2.614 0.537 - 313 1 2 0 -0.0026 14 0 0 0 1.24E+08 9.12E+07 - - - 7.0799 0.9993 221125_WJC_METTL3_EV_vs_WT_F09.05650.05650.2 1.55E-05 13/26 R.VTSSEPPNPASSSK.S sp|Q92575|UBXN4_HUMAN 1 1386.6627 1.21 127209 5650 2 1386.659855 694.3386 UBX domain-containing protein 4 OS=Homo sapiens OX=9606 GN=UBXN4 PE=1 SV=2 5.97 1553.2 - 829903 - - - -2.043 - 2.011 0.37 - 312.2 1 2 0 -0.0028 14 0 0 0 7.92E+06 6.57E+06 - - - 3.5261 1 221125_WJC_METTL3_EV_vs_WT_F09.05653.05653.2 0.000604 15/30 K.SAEIDSDDTGGSAAQK[136.11].Q sp|P33176|KINH_HUMAN 1 1558.6838 1.4 127212 5653 2 1558.679318 780.3492 Kinesin-1 heavy chain OS=Homo sapiens OX=9606 GN=KIF5B PE=1 SV=1 3.84 1553.5 - 663920 - - - -2.8909 - 3.018 0.691 - 608.4 1 2 0 -0.0045 16 0 0 0 1.50E+07 1.07E+07 - - - 6.859 1 221125_WJC_METTL3_EV_vs_WT_F09.05658.05658.3 7.46E-06 Dec-52 R.AAHASADLPEASSK.K "sp|Q5JSZ5|PRC2B_HUMAN,tr|A0A804HKC3|A0A804HKC3_HUMAN,tr|A0A804HJR4|A0A804HJR4_HUMAN" 3 1353.6525 1.35 127215 5658 3 1353.649875 452.2248 Protein PRRC2B OS=Homo sapiens OX=9606 GN=PRRC2B PE=1 SV=2 5.32 1554.1 - 1.75E+07 - - - -1.9082 - 2.345 0.518 - 271.3 1 2 0 -0.0026 14 0 0 0 1.23E+08 9.09E+07 - - - 6.5794 1 221125_WJC_METTL3_EV_vs_WT_F09.05659.05659.2 1.22E-12 19/42 K.LSSVASNGGGAGGAGGGAAGDK.D sp|Q96F45|ZN503_HUMAN 1 1716.8027 1.85 127216 5659 2 1716.80041 859.4086 Zinc finger protein 503 OS=Homo sapiens OX=9606 GN=ZNF503 PE=1 SV=1 5.84 1554.2 - 1.33E+06 - - - -1.3362 - 4.045 0.676 - 973.9 1 2 0 -0.0023 22 0 0 0 1.14E+07 6.15E+06 - - - 7.469 0.9999 221125_WJC_METTL3_EV_vs_WT_F09.05663.05663.3 2.92E-05 16/84 K.LSSVASNGGGAGGAGGGAAGDK[136.11].D sp|Q96F45|ZN503_HUMAN 1 1724.8169 2.89 127220 5663 3 1724.815492 575.9462 Zinc finger protein 503 OS=Homo sapiens OX=9606 GN=ZNF503 PE=1 SV=1 5.84 1554.6 - 591154 - - - -0.8186 - 2.682 0.45 - 162.7 1 2 0 -0.0014 22 0 0 0 7.88E+06 2.73E+06 - - - 5.8956 1 221125_WJC_METTL3_EV_vs_WT_F09.05668.05668.3 3.84E-07 14/44 K.NNRPSEGPLQTR.L "sp|Q00610|CLH1_HUMAN,tr|A0A087WVQ6|A0A087WVQ6_HUMAN" 2 1367.6906 0.95 127223 5668 3 1367.689465 456.9041 Clathrin heavy chain 1 OS=Homo sapiens OX=9606 GN=CLTC PE=1 SV=5 9.6 1555.2 - 6.87E+06 - - - -0.8116 - 2.96 0.534 - 347.8 1 2 0 -0.0011 12 0 0 0 8.80E+07 9.27E+07 - - - 7.5012 1 221125_WJC_METTL3_EV_vs_WT_F09.05676.05676.2 2.87E-05 28-Nov K.GPAPAPQQC[160.03]SEPETK[136.11].W "sp|Q3YEC7|RABL6_HUMAN,tr|G3V154|G3V154_HUMAN" 2 1603.7392 1.87 127231 5676 2 1603.736169 802.8769 Rab-like protein 6 OS=Homo sapiens OX=9606 GN=RABL6 PE=1 SV=2 4.53 1555.9 - 242753 - - - -1.8719 - 2.373 0.621 - 312.2 1 2 0 -0.003 15 0 0 0 8.59E+06 4.59E+06 - - - 5.7513 0.9982 221125_WJC_METTL3_EV_vs_WT_F09.05679.05679.3 2.43E-05 15/48 R.TK[136.11]TPGPGAQSALR[166.11].A "sp|P62263|RS14_HUMAN,tr|A0A2R8Y811|A0A2R8Y811_HUMAN,tr|E5RH77|E5RH77_HUMAN" 3 1300.7218 1.26 127232 5679 3 1300.720793 434.5812 40S ribosomal protein S14 OS=Homo sapiens OX=9606 GN=RPS14 PE=1 SV=3 11 1556.4 - 2.44E+06 - - - -0.7888 - 2.694 0.249 - 353.3 1 2 1 -0.001 13 0 0 0 3.81E+07 3.03E+07 - - - 4.0028 0.9999 221125_WJC_METTL3_EV_vs_WT_F09.05682.05682.3 3.04E-07 21/52 K.VETQTEELK[136.11]QNESR[166.11].T "sp|Q6KC79|NIPBL_HUMAN,tr|A0A590UJS4|A0A590UJS4_HUMAN" 2 1707.8394 1.14 127235 5682 3 1707.839253 570.2871 Nipped-B-like protein OS=Homo sapiens OX=9606 GN=NIPBL PE=1 SV=2 4.49 1556.7 - 672033 - - - -0.1019 - 3.383 0.544 - 789.2 1 2 1 -0.0002 14 0 0 0 3.81E+07 3.34E+07 - - - 7.8439 0.9997 221125_WJC_METTL3_EV_vs_WT_F09.05683.05683.3 0.00011 Dec-84 K.LSSVASNGGGAGGAGGGAAGDK.D sp|Q96F45|ZN503_HUMAN 1 1716.8027 2.89 127236 5683 3 1716.803233 573.2748 Zinc finger protein 503 OS=Homo sapiens OX=9606 GN=ZNF503 PE=1 SV=1 5.84 1556.8 - 508975 - - - 0.3081 - 2.071 0.346 - 54.4 1 2 0 0.0005 22 0 0 0 7.88E+06 2.73E+06 - - - 4.1235 0.9996 221125_WJC_METTL3_EV_vs_WT_F09.05685.05685.2 9.69E-05 22-Jul K.NNRPSEGPLQTR.L "sp|Q00610|CLH1_HUMAN,tr|A0A087WVQ6|A0A087WVQ6_HUMAN" 2 1367.6906 1.47 127238 5685 2 1367.689459 684.8526 Clathrin heavy chain 1 OS=Homo sapiens OX=9606 GN=CLTC PE=1 SV=5 9.6 1557.1 - 489969 - - - -0.816 - 1.627 0.428 - 47.6 1 2 0 -0.0011 12 0 0 0 5.87E+06 4.00E+06 - - - 3.4825 0.9259 221125_WJC_METTL3_EV_vs_WT_F09.05687.05687.2 0.254 22-Aug K.NNR[166.11]PSEGPLQTR[166.11].L "sp|Q00610|CLH1_HUMAN,tr|A0A087WVQ6|A0A087WVQ6_HUMAN" 2 1387.7071 1.47 127240 5687 2 1387.713867 694.8608 Clathrin heavy chain 1 OS=Homo sapiens OX=9606 GN=CLTC PE=1 SV=5 9.6 1557.4 - 340701 - - - 4.8656 - 1.281 0.203 - 69.7 1 2 0 0.0068 12 0 0 0 5.87E+06 4.00E+06 - - - 1.1898 1 221125_WJC_METTL3_EV_vs_WT_F09.05690.05690.2 9.28E-07 30-Dec K.SAEIDSDDTGGSAAQK.Q sp|P33176|KINH_HUMAN 1 1550.6696 1.4 127242 5690 2 1550.669406 776.3421 Kinesin-1 heavy chain OS=Homo sapiens OX=9606 GN=KIF5B PE=1 SV=1 3.84 1557.7 - 439480 - - - -0.1406 - 2.697 0.646 - 358.7 1 2 0 -0.0002 16 0 0 0 1.50E+07 1.07E+07 - - - 6.2515 0.9999 221125_WJC_METTL3_EV_vs_WT_F09.05693.05693.2 9.83E-08 24-Dec K.EQTFSGGTSQDTK.A "sp|Q9Y2W1|TR150_HUMAN,tr|A0A3B3ITZ9|A0A3B3ITZ9_HUMAN" 2 1384.6107 2.5 127244 5693 2 1384.609934 693.3126 Thyroid hormone receptor-associated protein 3 OS=Homo sapiens OX=9606 GN=THRAP3 PE=1 SV=2 4.37 1558 - 2.49E+06 - - - -0.5193 - 2.337 0.606 - 477.8 1 2 0 -0.0007 13 0 0 0 2.62E+09 1.05E+09 - - - 5.6953 0.9998 221125_WJC_METTL3_EV_vs_WT_F09.05694.05694.2 0.000154 24-Nov K.EQTFSGGTSQDTK[136.11].A "sp|Q9Y2W1|TR150_HUMAN,tr|A0A3B3ITZ9|A0A3B3ITZ9_HUMAN" 2 1392.6249 2.5 127245 5694 2 1392.623194 697.3197 Thyroid hormone receptor-associated protein 3 OS=Homo sapiens OX=9606 GN=THRAP3 PE=1 SV=2 4.37 1558.1 - 1.08E+06 - - - -1.1913 - 2.224 0.458 - 359.7 1 2 0 -0.0017 13 0 0 0 2.62E+09 1.05E+09 - - - 4.4747 1 221125_WJC_METTL3_EV_vs_WT_F09.05701.05701.2 1.71E-13 17/40 K.GAAEGSGGDGEGPPGEAGAEK.S sp|P31277|HXD11_HUMAN 1 1798.7606 5.18 127252 5701 2 1798.757804 900.3876 Homeobox protein Hox-D11 OS=Homo sapiens OX=9606 GN=HOXD11 PE=3 SV=3 3.91 1558.9 - 430863 - - - -1.5349 - 3.794 0.731 - 664.6 1 2 0 -0.0028 21 0 0 0 8.13E+06 1.57E+06 - - - 7.7176 0.8737 221125_WJC_METTL3_EV_vs_WT_F09.05702.05702.3 0.221 Jul-56 K.RQAGAGSSSPEAPLR.S "sp|Q71RG4|TMUB2_HUMAN,tr|K7EKW3|K7EKW3_HUMAN,tr|E7ESS3|E7ESS3_HUMAN" 3 1482.7539 5.09 127253 5702 3 1482.7584 495.2586 Transmembrane and ubiquitin-like domain-containing protein 2 OS=Homo sapiens OX=9606 GN=TMUB2 PE=1 SV=2 9.6 1559 - 309888 - - - 3.0329 - 1.542 0.137 - 34.6 2 2 0 0.0045 15 0 0 0 1.62E+06 3.19E+05 - - - 1.0569 1 221125_WJC_METTL3_EV_vs_WT_F09.05707.05707.2 3.04E-13 18/32 L.VSGLNSSASEPAK[136.11]EPAK[136.11].K "sp|Q86U44|MTA70_HUMAN,tr|F5H6D8|F5H6D8_HUMAN,tr|H0YFV6|H0YFV6_HUMAN,tr|B4DTN4|B4DTN4_HUMAN" 4 1686.8759 0.001 127256 5707 2 1686.872042 844.4452 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 6.11 1559.7 - 675328 - - - -2.3043 - 3.262 0.689 - 1054.8 1 1 1 -0.0039 17 0 0 0 0.00E+00 1.64E+07 - - - 7.0356 1 221125_WJC_METTL3_EV_vs_WT_F09.05711.05711.3 1.17E-07 15/52 K.AGPEC[160.03]LHC[160.03]EEGC[160.03]SK[136.11].S sp|Q6ZNB6|NFXL1_HUMAN 1 1640.6473 0.52 127260 5711 3 1640.645155 547.8897 NF-X1-type zinc finger protein NFXL1 OS=Homo sapiens OX=9606 GN=NFXL1 PE=1 SV=2 4.75 1560 - 494089 - - - -1.2842 - 2.679 0.632 - 447.4 1 2 0 -0.0021 14 0 0 0 5.84E+06 1.12E+07 - - - 8.2044 0.9839 221125_WJC_METTL3_EV_vs_WT_F09.05715.05715.3 0.0409 Nov-48 K.DVQPGSVADR[166.11]DQR[166.11].L "sp|Q8NI35|INADL_HUMAN,tr|A0A2R8Y549|A0A2R8Y549_HUMAN,tr|A0A0X1KG69|A0A0X1KG69_HUMAN,tr|A0A0U1RR46|A0A0U1RR46_HUMAN,tr|A0A087WUZ6|A0A087WUZ6_HUMAN" 5 1461.7075 1.79 127264 5715 3 1461.7071 488.2431 InaD-like protein OS=Homo sapiens OX=9606 GN=PATJ PE=1 SV=3 4.43 1560.6 - 381444 - - - -0.2798 - 1.49 0.254 - 127.3 1 2 1 -0.0004 13 0 0 0 4.76E+06 2.66E+06 - - - 2.4529 1 221125_WJC_METTL3_EV_vs_WT_F09.05717.05717.3 2.66E-05 Dec-80 K.GAAEGSGGDGEGPPGEAGAEK.S sp|P31277|HXD11_HUMAN 1 1798.7606 8.73 127266 5717 3 1798.759444 600.5941 Homeobox protein Hox-D11 OS=Homo sapiens OX=9606 GN=HOXD11 PE=3 SV=3 3.91 1560.8 - 284118 - - - -0.6232 - 1.881 0.552 - 103.3 1 2 0 -0.0011 21 0 0 0 2.21E+06 2.54E+05 - - - 6.2087 1 221125_WJC_METTL3_EV_vs_WT_F09.05720.05720.2 3.58E-09 15/30 V.SGLNSSASEPAK[136.11]EPAK[136.11].K "sp|Q86U44|MTA70_HUMAN,tr|F5H6D8|F5H6D8_HUMAN,tr|H0YFV6|H0YFV6_HUMAN,tr|B4DTN4|B4DTN4_HUMAN" 4 1587.8075 0.001 127269 5720 2 1587.806388 794.911 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 5.86 1561.2 - 150156 - - - -0.7098 - 2.915 0.64 - 324.9 1 1 1 -0.0011 16 0 0 0 0.00E+00 1.79E+06 - - - 6.398 0.9998 221125_WJC_METTL3_EV_vs_WT_F09.05725.05725.3 0.00634 Aug-44 R.DYSDHPSGGSYR.D "sp|Q96E39|RMXL1_HUMAN,sp|P38159|RBMX_HUMAN,tr|H3BUY5|H3BUY5_HUMAN,tr|H3BT71|H3BT71_HUMAN,tr|H0Y6E7|H0Y6E7_HUMAN" 5 1339.5429 1.53 127272 5725 3 1339.540268 447.5216 "RNA binding motif protein, X-linked-like-1 OS=Homo sapiens OX=9606 GN=RBMXL1 PE=1 SV=1" 5.21 1561.8 - 1.07E+07 - - - -1.9708 - 1.429 0.513 - 72 1 2 0 -0.0026 12 0 0 0 2.00E+08 1.31E+08 - - - 5.2482 0.976 221125_WJC_METTL3_EV_vs_WT_F09.05726.05726.3 5.35E-05 15/64 L.VSGLNSSASEPAK[136.11]EPAK[136.11].K "sp|Q86U44|MTA70_HUMAN,tr|F5H6D8|F5H6D8_HUMAN,tr|H0YFV6|H0YFV6_HUMAN,tr|B4DTN4|B4DTN4_HUMAN" 4 1686.8759 0 127273 5726 3 1686.871382 563.2993 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 6.11 1561.8 - 3.55E+07 - - - -2.6955 - 3.076 0.532 - 258.3 1 1 1 -0.0045 17 0 0 0 7.37E+05 4.37E+08 - - - 7.3086 1 221125_WJC_METTL3_EV_vs_WT_F09.05728.05728.3 0.000104 Nov-44 R.DYSDHPSGGSYR[166.11].D "sp|Q96E39|RMXL1_HUMAN,sp|P38159|RBMX_HUMAN,tr|H3BUY5|H3BUY5_HUMAN,tr|H3BT71|H3BT71_HUMAN,tr|H0Y6E7|H0Y6E7_HUMAN" 5 1349.5512 1.54 127275 5728 3 1349.548778 450.8577 "RNA binding motif protein, X-linked-like-1 OS=Homo sapiens OX=9606 GN=RBMXL1 PE=1 SV=1" 5.21 1561.9 - 7.09E+06 - - - -1.7784 - 1.815 0.635 - 139.3 1 2 0 -0.0024 12 0 0 0 2.00E+08 1.29E+08 - - - 7.2712 0.9997 221125_WJC_METTL3_EV_vs_WT_F09.05729.05729.3 0.000236 Dec-48 K.EQTFSGGTSQDTK.A "sp|Q9Y2W1|TR150_HUMAN,tr|A0A3B3ITZ9|A0A3B3ITZ9_HUMAN" 2 1384.6107 1.43 127276 5729 3 1384.607957 462.5442 Thyroid hormone receptor-associated protein 3 OS=Homo sapiens OX=9606 GN=THRAP3 PE=1 SV=2 4.37 1561.9 - 6.54E+06 - - - -1.9471 - 2.007 0.397 - 182.4 1 2 0 -0.0027 13 0 0 0 6.38E+07 4.47E+07 - - - 4.8542 0.9997 221125_WJC_METTL3_EV_vs_WT_F09.05745.05745.2 1.99E-06 22-Nov R.DYSDHPSGGSYR[166.11].D "sp|Q96E39|RMXL1_HUMAN,sp|P38159|RBMX_HUMAN,tr|H3BUY5|H3BUY5_HUMAN,tr|H3BT71|H3BT71_HUMAN,tr|H0Y6E7|H0Y6E7_HUMAN" 5 1349.5512 1.44 127289 5745 2 1349.54803 675.7829 "RNA binding motif protein, X-linked-like-1 OS=Homo sapiens OX=9606 GN=RBMXL1 PE=1 SV=1" 5.21 1563.8 - 1.13E+06 - - - -2.3326 - 1.745 0.642 - 263.2 1 2 0 -0.0031 12 0 0 0 2.00E+07 1.38E+07 - - - 5.2467 0.9891 221125_WJC_METTL3_EV_vs_WT_F09.05746.05746.3 0.0108 Aug-48 K.EQTFSGGTSQDTK[136.11].A "sp|Q9Y2W1|TR150_HUMAN,tr|A0A3B3ITZ9|A0A3B3ITZ9_HUMAN" 2 1392.6249 1.45 127290 5746 3 1392.621505 465.2156 Thyroid hormone receptor-associated protein 3 OS=Homo sapiens OX=9606 GN=THRAP3 PE=1 SV=2 4.37 1563.8 - 4.40E+06 - - - -2.4041 - 1.553 0.23 - 79.2 1 2 0 -0.0033 13 0 0 0 6.38E+07 4.38E+07 - - - 2.2968 0.9253 221125_WJC_METTL3_EV_vs_WT_F09.05748.05748.3 0.185 Aug-44 K.VNTLIRPDGEKK.A "sp|P62750|RL23A_HUMAN,tr|K7EMA7|K7EMA7_HUMAN,tr|H7BY10|H7BY10_HUMAN,tr|K7ERT8|K7ERT8_HUMAN,tr|A8MUS3|A8MUS3_HUMAN,tr|K7EJV9|K7EJV9_HUMAN" 6 1368.7725 0.61 127292 5748 3 1368.768176 457.2648 60S ribosomal protein L23a OS=Homo sapiens OX=9606 GN=RPL23A PE=1 SV=1 8.56 1564 - 1.36E+06 - - - -3.1693 - 1.511 0.157 - 82.6 1 2 0 -0.0043 12 0 0 0 2.42E+07 3.97E+07 - - - 1.4333 1 221125_WJC_METTL3_EV_vs_WT_F09.05749.05749.2 6.04E-08 15/28 R.TTASEPVEQSEATSK[136.11].D sp|Q15007|FL2D_HUMAN 1 1571.7406 0.8 127293 5749 2 1571.737487 786.8776 Pre-mRNA-splicing regulator WTAP OS=Homo sapiens OX=9606 GN=WTAP PE=1 SV=2 4.25 1564.1 - 811823 - - - -1.9876 - 2.809 0.635 - 470.3 1 2 0 -0.0031 15 0 0 0 2.46E+07 3.06E+07 - - - 6.2694 0.9479 221125_WJC_METTL3_EV_vs_WT_F09.05753.05753.3 0.229 Sep-44 K.VNTLIR[166.11]PDGEK[136.11]K[136.11].A "sp|P62750|RL23A_HUMAN,tr|K7EMA7|K7EMA7_HUMAN,tr|H7BY10|H7BY10_HUMAN,tr|K7ERT8|K7ERT8_HUMAN,tr|A8MUS3|A8MUS3_HUMAN,tr|K7EJV9|K7EJV9_HUMAN" 6 1394.8092 0.61 127294 5753 3 1394.806797 465.9437 60S ribosomal protein L23a OS=Homo sapiens OX=9606 GN=RPL23A PE=1 SV=1 8.56 1564.7 - 3.29E+06 - - - -1.7113 - 1.63 0.104 - 84.9 1 2 0 -0.0024 12 0 0 0 2.41E+07 3.97E+07 - - - 1.0531 1 221125_WJC_METTL3_EV_vs_WT_F09.05755.05755.2 1.44E-07 17/28 R.TTASEPVEQSEATSK.D sp|Q15007|FL2D_HUMAN 1 1563.7264 0.8 127296 5755 2 1563.723551 782.8705 Pre-mRNA-splicing regulator WTAP OS=Homo sapiens OX=9606 GN=WTAP PE=1 SV=2 4.25 1564.9 - 1.25E+06 - - - -1.829 - 2.961 0.606 - 755 1 2 0 -0.0029 15 0 0 0 2.46E+07 3.06E+07 - - - 6.1848 0.9998 221125_WJC_METTL3_EV_vs_WT_F09.05768.05768.2 1.17E-05 26-Nov R.QDTTSIQQGETASK[136.11].E sp|P78382|S35A1_HUMAN 1 1500.7147 1.11 127307 5768 2 1500.712896 751.3646 CMP-sialic acid transporter OS=Homo sapiens OX=9606 GN=SLC35A1 PE=1 SV=1 4.37 1566.6 - 140774 - - - -1.2228 - 1.91 0.576 - 430.2 1 2 0 -0.0018 14 0 0 0 1.35E+06 1.21E+06 - - - 4.9186 1 221125_WJC_METTL3_EV_vs_WT_F09.05781.05781.2 8.47E-08 14/28 R.SGGGSGGSGGQVSLK.K sp|Q9H7N4|SFR19_HUMAN 1 1233.5949 2.25 127315 5781 2 1233.595426 617.8047 "Splicing factor, arginine\serine-rich 19 OS=Homo sapiens OX=9606 GN=SCAF1 PE=1 SV=3" 8.47 1568.2 - 530510 - - - 0.3915 - 3.249 0.637 - 895 1 2 0 0.0005 15 0 0 0 5.58E+06 2.48E+06 - - - 6.6428 0.9988 221125_WJC_METTL3_EV_vs_WT_F09.05782.05782.3 0.0532 Sep-40 R.NSHSSIAEIQK.D "sp|Q8NEZ2|VP37A_HUMAN,tr|E5RG91|E5RG91_HUMAN" 2 1212.6099 0.45 127316 5782 3 1212.610099 405.2106 Vacuolar protein sorting-associated protein 37A OS=Homo sapiens OX=9606 GN=VPS37A PE=1 SV=1 6.75 1568.3 - 272616 - - - 0.193 - 1.671 0.287 - 117 1 2 0 0.0002 11 0 0 0 3.65E+06 8.06E+06 - - - 3.1982 0.9997 221125_WJC_METTL3_EV_vs_WT_F09.05784.05784.3 0.0195 Sep-36 R.KESEFDDEPK.F "sp|Q9Y2W1|TR150_HUMAN,tr|A0A3B3ITZ9|A0A3B3ITZ9_HUMAN" 2 1222.5354 2.82 127318 5784 3 1222.535677 408.5191 Thyroid hormone receptor-associated protein 3 OS=Homo sapiens OX=9606 GN=THRAP3 PE=1 SV=2 4.18 1568.6 - 240871 - - - 0.2568 - 1.455 0.401 - 118.9 1 2 0 0.0003 10 0 0 0 2.33E+07 8.26E+06 - - - 4.1058 1 221125_WJC_METTL3_EV_vs_WT_F09.05785.05785.2 2.49E-07 13/26 K.QQVEQSSASQTGIK.Q "sp|Q9H4A3|WNK1_HUMAN,tr|F5GWT4|F5GWT4_HUMAN,tr|A0A6Q8PFM0|A0A6Q8PFM0_HUMAN" 3 1489.7372 1.6 127319 5785 2 1489.737449 745.8759 Serine\threonine-protein kinase WNK1 OS=Homo sapiens OX=9606 GN=WNK1 PE=1 SV=2 6 1568.7 - 190435 - - - 0.1336 - 2.555 0.631 - 594.8 1 2 0 0.0002 14 0 0 0 4.11E+06 2.57E+06 - - - 6.0555 1 221125_WJC_METTL3_EV_vs_WT_F09.05786.05786.2 2.85E-08 22-Sep K.TC[160.03]NC[160.03]ETEDYGEK.F "sp|Q00839|HNRPU_HUMAN,tr|A0A1W2PQL0|A0A1W2PQL0_HUMAN,tr|A0A1W2PPL4|A0A1W2PPL4_HUMAN,tr|A0A1W2PQ74|A0A1W2PQ74_HUMAN,tr|Q5RI18|Q5RI18_HUMAN,tr|A0A1W2PP35|A0A1W2PP35_HUMAN,tr|A0A1W2PPS1|A0A1W2PPS1_HUMAN,tr|A0A1W2PRZ7|A0A1W2PRZ7_HUMAN,tr|A0A1W2PPH7|A0A1W2PPH7_HUMAN,tr|A0A1W2PP34|A0A1W2PP34_HUMAN,tr|A0A1X7SBS1|A0A1X7SBS1_HUMAN" 11 1504.5446 1.1 127320 5786 2 1504.545222 753.2796 Heterogeneous nuclear ribonucleoprotein U OS=Homo sapiens OX=9606 GN=HNRNPU PE=1 SV=6 4 1568.8 - 153269 - - - 0.3975 - 2.224 0.686 - 272.3 1 2 0 0.0006 12 0 0 0 5.83E+06 5.28E+06 - - - 6.2107 1 221125_WJC_METTL3_EV_vs_WT_F09.05791.05791.2 1.96E-05 13/28 R.SGGGSGGSGGQVSLK[136.11].K sp|Q9H7N4|SFR19_HUMAN 1 1241.6091 2.25 127323 5791 2 1241.610613 621.8118 "Splicing factor, arginine\serine-rich 19 OS=Homo sapiens OX=9606 GN=SCAF1 PE=1 SV=3" 8.47 1569.5 - 287436 - - - 1.1839 - 2.931 0.574 - 674.3 1 2 0 0.0015 15 0 0 0 5.58E+06 2.48E+06 - - - 5.9239 1 221125_WJC_METTL3_EV_vs_WT_F09.05792.05792.2 9.01E-07 24-Dec T.NTGPNNSNTTFQK.R "sp|Q9NYF8|BCLF1_HUMAN,tr|H0YF14|H0YF14_HUMAN" 2 1421.6535 2.36 127324 5792 2 1421.654234 711.834 Bcl-2-associated transcription factor 1 OS=Homo sapiens OX=9606 GN=BCLAF1 PE=1 SV=2 8.75 1569.7 - 270863 - - - 0.5015 - 2.625 0.629 - 612.8 1 1 0 0.0007 13 0 0 0 1.92E+08 8.14E+07 - - - 6.1635 0.9999 221125_WJC_METTL3_EV_vs_WT_F09.05793.05793.3 0.00133 Sep-56 R.TTASEPVEQSEATSK.D sp|Q15007|FL2D_HUMAN 1 1563.7264 0.9 127325 5793 3 1563.729414 522.2494 Pre-mRNA-splicing regulator WTAP OS=Homo sapiens OX=9606 GN=WTAP PE=1 SV=2 4.25 1569.8 - 148105 - - - 1.9204 - 2.223 0.45 - 114.3 1 2 0 0.003 15 0 0 0 2.85E+06 3.16E+06 - - - 5.6407 1 221125_WJC_METTL3_EV_vs_WT_F09.05794.05794.2 3.47E-06 22-Nov K.TC[160.03]NC[160.03]ETEDYGEK[136.11].F "sp|Q00839|HNRPU_HUMAN,tr|A0A1W2PQL0|A0A1W2PQL0_HUMAN,tr|A0A1W2PPL4|A0A1W2PPL4_HUMAN,tr|A0A1W2PQ74|A0A1W2PQ74_HUMAN,tr|Q5RI18|Q5RI18_HUMAN,tr|A0A1W2PP35|A0A1W2PP35_HUMAN,tr|A0A1W2PPS1|A0A1W2PPS1_HUMAN,tr|A0A1W2PRZ7|A0A1W2PRZ7_HUMAN,tr|A0A1W2PPH7|A0A1W2PPH7_HUMAN,tr|A0A1W2PP34|A0A1W2PP34_HUMAN,tr|A0A1X7SBS1|A0A1X7SBS1_HUMAN" 11 1512.5588 1.1 127326 5794 2 1512.557652 757.2867 Heterogeneous nuclear ribonucleoprotein U OS=Homo sapiens OX=9606 GN=HNRNPU PE=1 SV=6 4 1569.9 - 135548 - - - -0.7748 - 2.247 0.758 - 425.2 1 2 0 -0.0012 12 0 0 0 5.83E+06 5.28E+06 - - - 6.7694 1 221125_WJC_METTL3_EV_vs_WT_F09.05795.05795.2 9.41E-10 24-Oct T.NTGPNNSNTTFQK[136.11].R "sp|Q9NYF8|BCLF1_HUMAN,tr|H0YF14|H0YF14_HUMAN" 2 1429.6677 2.36 127327 5795 2 1429.671365 715.8411 Bcl-2-associated transcription factor 1 OS=Homo sapiens OX=9606 GN=BCLAF1 PE=1 SV=2 8.75 1570 - 126841 - - - 2.5488 - 2.485 0.657 - 445.5 1 1 0 0.0036 13 0 0 0 1.92E+08 8.14E+07 - - - 6.2287 0.9999 221125_WJC_METTL3_EV_vs_WT_F09.05796.05796.2 5.61E-05 26-Oct K.QQVEQSSASQTGIK[136.11].Q "sp|Q9H4A3|WNK1_HUMAN,tr|F5GWT4|F5GWT4_HUMAN,tr|A0A6Q8PFM0|A0A6Q8PFM0_HUMAN" 3 1497.7514 1.65 127328 5796 2 1497.752474 749.883 Serine\threonine-protein kinase WNK1 OS=Homo sapiens OX=9606 GN=WNK1 PE=1 SV=2 6 1570.2 - 112287 - - - 0.6837 - 2.093 0.583 - 234.8 1 2 0 0.001 14 0 0 0 3.52E+06 2.14E+06 - - - 5.2002 0.9995 221125_WJC_METTL3_EV_vs_WT_F09.05797.05797.3 0.0354 Jul-52 K.AGPEC[160.03]LHC[160.03]EEGC[160.03]SK.S sp|Q6ZNB6|NFXL1_HUMAN 1 1632.6331 0.47 127329 5797 3 1632.633448 545.2183 NF-X1-type zinc finger protein NFXL1 OS=Homo sapiens OX=9606 GN=NFXL1 PE=1 SV=2 4.75 1570.3 - 105801 - - - 0.2364 - 1.278 0.411 - 55.2 1 2 0 0.0004 14 0 0 0 1.49E+06 3.15E+06 - - - 3.774 0.9324 221125_WJC_METTL3_EV_vs_WT_F09.05802.05802.2 1.59 14-Jun R.TSIEVGVK.G sp|Q03052|PO3F1_HUMAN 1 831.4702 999 127332 5802 2 831.471376 416.7424 "POU domain, class 3, transcription factor 1 OS=Homo sapiens OX=9606 GN=POU3F1 PE=2 SV=3" 5.66 1571 - 1.38E+06 - - - 1.4348 - 1.225 0.032 - 126.1 3 2 0 0.0012 8 0 0 0 4.39E+08 0.00E+00 - - - -0.3241 0.9998 221125_WJC_METTL3_EV_vs_WT_F09.05805.05805.2 6.28E-06 26-Dec K.TTSESSSSPSASLK.G "sp|Q96CB8|INT12_HUMAN,tr|A0A087WXN4|A0A087WXN4_HUMAN" 2 1367.6416 1.27 127335 5805 2 1367.643967 684.8281 Integrator complex subunit 12 OS=Homo sapiens OX=9606 GN=INTS12 PE=1 SV=1 5.66 1571.4 - 294862 - - - 1.7168 - 2.425 0.532 - 564.4 1 2 0 0.0023 14 0 0 0 1.03E+07 8.12E+06 - - - 5.1926 1 221125_WJC_METTL3_EV_vs_WT_F09.05806.05806.2 9.48E-09 14/26 K.TTSESSSSPSASLK[136.11].G "sp|Q96CB8|INT12_HUMAN,tr|A0A087WXN4|A0A087WXN4_HUMAN" 2 1375.6558 1.27 127336 5806 2 1375.656939 688.8352 Integrator complex subunit 12 OS=Homo sapiens OX=9606 GN=INTS12 PE=1 SV=1 5.66 1571.5 - 247207 - - - 0.8142 - 2.855 0.62 - 751.4 1 2 0 0.0011 14 0 0 0 1.03E+07 8.12E+06 - - - 6.2526 1 221125_WJC_METTL3_EV_vs_WT_F09.05807.05807.3 1.21E-07 Nov-48 R.K[136.11]GTDDSMTLQSQK[136.11].F "sp|O00422|SAP18_HUMAN,tr|H7BZW6|H7BZW6_HUMAN" 2 1453.7054 1.37 127337 5807 3 1453.706638 485.5757 Histone deacetylase complex subunit SAP18 OS=Homo sapiens OX=9606 GN=SAP18 PE=1 SV=1 5.96 1571.7 - 153425 - - - 0.8805 - 2.349 0.572 - 215.5 1 2 0 0.0013 13 0 0 0 3.73E+07 2.73E+07 - - - 7.2323 0.9995 221125_WJC_METTL3_EV_vs_WT_F09.05811.05811.3 0.000416 Dec-40 K.LLEQYK[136.11]EESK[136.11]K[136.11].A "sp|Q00839|HNRPU_HUMAN,tr|A0A1W2PQL0|A0A1W2PQL0_HUMAN,tr|A0A1W2PPL4|A0A1W2PPL4_HUMAN,tr|Q5RI18|Q5RI18_HUMAN,tr|A0A1W2PP35|A0A1W2PP35_HUMAN,tr|A0A1W2PPS1|A0A1W2PPS1_HUMAN,tr|A0A1W2PPH7|A0A1W2PPH7_HUMAN,tr|A0A1W2PQD4|A0A1W2PQD4_HUMAN,tr|A0A1W2PP34|A0A1W2PP34_HUMAN,tr|A0A1X7SBS1|A0A1X7SBS1_HUMAN" 10 1417.7879 0.94 127339 5811 3 1417.788837 473.6032 Heterogeneous nuclear ribonucleoprotein U OS=Homo sapiens OX=9606 GN=HNRNPU PE=1 SV=6 6.23 1572.2 - 806726 - - - 0.6637 - 2.353 0.379 - 195.1 1 2 1 0.0009 11 0 0 0 2.63E+09 2.78E+09 - - - 5.1961 1 221125_WJC_METTL3_EV_vs_WT_F09.05812.05812.3 7.69E-05 Nov-48 R.KGTDDSMTLQSQK.F "sp|O00422|SAP18_HUMAN,tr|H7BZW6|H7BZW6_HUMAN" 2 1437.677 1.37 127340 5812 3 1437.677747 480.2329 Histone deacetylase complex subunit SAP18 OS=Homo sapiens OX=9606 GN=SAP18 PE=1 SV=1 5.96 1572.3 - 371244 - - - 0.5488 - 2.479 0.483 - 257 1 2 0 0.0008 13 0 0 0 3.75E+07 2.74E+07 - - - 6.3862 0.9787 221125_WJC_METTL3_EV_vs_WT_F09.05814.05814.3 0.397 Jul-36 R.K[136.11]ESEFDDEPK[136.11].F "sp|Q9Y2W1|TR150_HUMAN,tr|A0A3B3ITZ9|A0A3B3ITZ9_HUMAN" 2 1238.5638 2.99 127342 5814 3 1238.565655 413.8619 Thyroid hormone receptor-associated protein 3 OS=Homo sapiens OX=9606 GN=THRAP3 PE=1 SV=2 4.18 1572.6 - 157218 - - - 1.5276 - 1.263 0.211 - 67.6 1 2 0 0.0019 10 0 0 0 3.86E+07 1.29E+07 - - - 1.5738 1 221125_WJC_METTL3_EV_vs_WT_F09.05818.05818.3 3.31E-06 13/44 K.DQDELK[136.11]PGPTNR[166.11].S sp|Q14151|SAFB2_HUMAN 1 1386.6858 1.03 127345 5818 3 1386.687112 463.2359 Scaffold attachment factor B2 OS=Homo sapiens OX=9606 GN=SAFB2 PE=1 SV=1 4.56 1573.1 - 1.15E+06 - - - 0.9267 - 2.147 0.492 - 180 1 2 0 0.0013 12 0 0 0 3.20E+07 3.11E+07 - - - 6.1428 0.9999 221125_WJC_METTL3_EV_vs_WT_F09.05820.05820.3 0.00374 Dec-44 K.DQDELKPGPTNR.S sp|Q14151|SAFB2_HUMAN 1 1368.6634 1.09 127346 5820 3 1368.661422 457.2284 Scaffold attachment factor B2 OS=Homo sapiens OX=9606 GN=SAFB2 PE=1 SV=1 4.56 1573.3 - 1.59E+06 - - - -1.4138 - 1.963 0.439 - 143.7 1 2 0 -0.0019 12 0 0 0 3.18E+07 2.92E+07 - - - 5.3034 0.9983 221125_WJC_METTL3_EV_vs_WT_F09.05829.05829.2 0.0248 18-May R.KESEFDDEPK.F "sp|Q9Y2W1|TR150_HUMAN,tr|A0A3B3ITZ9|A0A3B3ITZ9_HUMAN" 2 1222.5354 4.18 127352 5829 2 1222.533809 612.275 Thyroid hormone receptor-associated protein 3 OS=Homo sapiens OX=9606 GN=THRAP3 PE=1 SV=2 4.18 1574.5 - 125862 - - - -1.2711 - 1.044 0.41 - 93.6 1 2 0 -0.0016 10 0 0 0 8.81E+06 2.11E+06 - - - 2.189 0.9891 221125_WJC_METTL3_EV_vs_WT_F09.05836.05836.3 0.0422 Oct-40 K.LLEQYKEESKK.A "sp|Q00839|HNRPU_HUMAN,tr|A0A1W2PQL0|A0A1W2PQL0_HUMAN,tr|A0A1W2PPL4|A0A1W2PPL4_HUMAN,tr|Q5RI18|Q5RI18_HUMAN,tr|A0A1W2PP35|A0A1W2PP35_HUMAN,tr|A0A1W2PPS1|A0A1W2PPS1_HUMAN,tr|A0A1W2PPH7|A0A1W2PPH7_HUMAN,tr|A0A1W2PQD4|A0A1W2PQD4_HUMAN,tr|A0A1W2PP34|A0A1W2PP34_HUMAN,tr|A0A1X7SBS1|A0A1X7SBS1_HUMAN" 10 1393.7453 0.94 127357 5836 3 1393.746985 465.589 Heterogeneous nuclear ribonucleoprotein U OS=Homo sapiens OX=9606 GN=HNRNPU PE=1 SV=6 6.23 1575.5 - 1.22E+06 - - - 1.2118 - 1.93 0.219 - 162.8 1 2 1 0.0017 11 0 0 0 2.65E+09 2.81E+09 - - - 2.8491 0.9999 221125_WJC_METTL3_EV_vs_WT_F09.05850.05850.3 0.00152 13/52 K.K[136.11]GPGEVAGTVTGQK[136.11].R "sp|Q86U44|MTA70_HUMAN,tr|F5H6D8|F5H6D8_HUMAN,tr|H0YFV6|H0YFV6_HUMAN,tr|B4DTN4|B4DTN4_HUMAN" 4 1343.738 0 127367 5850 3 1343.733837 448.9199 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 8.59 1577.4 - 9.90E+06 - - - -3.0824 - 2.67 0.508 - 313.7 1 2 0 -0.0041 14 0 0 0 3.92E+07 6.03E+11 - - - 6.8125 1 221125_WJC_METTL3_EV_vs_WT_F09.05860.05860.2 1.06E-05 19/26 K.K[136.11]GPGEVAGTVTGQK[136.11].R "sp|Q86U44|MTA70_HUMAN,tr|F5H6D8|F5H6D8_HUMAN,tr|H0YFV6|H0YFV6_HUMAN,tr|B4DTN4|B4DTN4_HUMAN" 4 1343.738 0 127373 5860 2 1343.737415 672.8763 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 8.59 1578.7 - 1.88E+06 - - - -0.4197 - 3.625 0.561 - 961.6 1 2 0 -0.0006 14 0 0 0 8.54E+08 2.86E+11 - - - 6.4162 0.9721 221125_WJC_METTL3_EV_vs_WT_F09.05867.05867.2 2.03 14-May R.GSEAGLVK.S "tr|A0A0G2JMN6|A0A0G2JMN6_HUMAN,tr|A0A0G2JQ24|A0A0G2JQ24_HUMAN,tr|A0A0G2JPA2|A0A0G2JPA2_HUMAN" 3 759.4127 12.5 127377 5867 2 759.412794 380.7136 Leukocyte immunoglobulin-like receptor subfamily A member 6 OS=Homo sapiens OX=9606 GN=LILRA6 PE=1 SV=1 6 1579.6 - 155159 - - - 0.1646 - 1.033 0.11 - 112.5 1 2 0 0.0001 8 0 0 0 1.02E+07 8.15E+05 - - - -0.0487 0.9454 221125_WJC_METTL3_EV_vs_WT_F09.05884.05884.3 0.156 May-36 R.R[166.11]DFAPPGQQK[136.11].R sp|Q9BVC6|TM109_HUMAN 1 1160.6057 0.87 127387 5884 3 1160.606502 387.8759 Transmembrane protein 109 OS=Homo sapiens OX=9606 GN=TMEM109 PE=1 SV=1 8.75 1582 - 59879 - - - 0.6686 - 1.206 0.204 - 28.5 16 2 0 0.0008 10 0 0 0 4.06E+06 4.68E+06 - - - 0.8039 1 221125_WJC_METTL3_EV_vs_WT_F09.05892.05892.2 2.38E-06 28-Dec K.SGGGGGGGGSSWGGR[166.11].S sp|Q13151|ROA0_HUMAN 1 1201.51 1.32 127391 5892 2 1201.510536 601.7623 Heterogeneous nuclear ribonucleoprotein A0 OS=Homo sapiens OX=9606 GN=HNRNPA0 PE=1 SV=1 9.47 1583 - 115049 - - - 0.4619 - 2.435 0.645 - 389.2 1 2 0 0.0006 15 0 0 0 1.04E+08 7.88E+07 - - - 5.9928 1 221125_WJC_METTL3_EV_vs_WT_F09.05910.05910.2 0.0006 16/28 K.SGGGGGGGGSSWGGR.S sp|Q13151|ROA0_HUMAN 1 1191.5017 1.32 127398 5910 2 1191.502059 596.7581 Heterogeneous nuclear ribonucleoprotein A0 OS=Homo sapiens OX=9606 GN=HNRNPA0 PE=1 SV=1 9.47 1585.8 - 446091 - - - 0.2921 - 2.792 0.619 - 520.6 1 2 0 0.0003 15 0 0 0 1.04E+08 7.88E+07 - - - 6.1372 0.8984 221125_WJC_METTL3_EV_vs_WT_F09.05916.05916.3 0.000578 Dec-36 L.LEQYK[136.11]EESK[136.11]K[136.11].A "sp|Q00839|HNRPU_HUMAN,tr|A0A1W2PQL0|A0A1W2PQL0_HUMAN,tr|A0A1W2PPL4|A0A1W2PPL4_HUMAN,tr|Q5RI18|Q5RI18_HUMAN,tr|A0A1W2PP35|A0A1W2PP35_HUMAN,tr|A0A1W2PPS1|A0A1W2PPS1_HUMAN,tr|A0A1W2PPH7|A0A1W2PPH7_HUMAN,tr|A0A1W2PQD4|A0A1W2PQD4_HUMAN,tr|A0A1W2PP34|A0A1W2PP34_HUMAN,tr|A0A1X7SBS1|A0A1X7SBS1_HUMAN" 10 1304.7038 0.91 127402 5916 3 1304.705007 435.9086 Heterogeneous nuclear ribonucleoprotein U OS=Homo sapiens OX=9606 GN=HNRNPU PE=1 SV=6 6.23 1586.5 - 785412 - - - 0.9006 - 1.979 0.354 - 174.1 1 1 1 0.0012 10 0 0 0 1.24E+08 1.36E+08 - - - 4.4799 0.9623 221125_WJC_METTL3_EV_vs_WT_F09.05925.05925.3 1.09 Sep-40 K.LLEQYK[136.11]EESKK[136.11].A "sp|Q00839|HNRPU_HUMAN,tr|A0A1W2PQL0|A0A1W2PQL0_HUMAN,tr|A0A1W2PPL4|A0A1W2PPL4_HUMAN,tr|Q5RI18|Q5RI18_HUMAN,tr|A0A1W2PP35|A0A1W2PP35_HUMAN,tr|A0A1W2PPS1|A0A1W2PPS1_HUMAN,tr|A0A1W2PPH7|A0A1W2PPH7_HUMAN,tr|A0A1W2PQD4|A0A1W2PQD4_HUMAN,tr|A0A1W2PP34|A0A1W2PP34_HUMAN,tr|A0A1X7SBS1|A0A1X7SBS1_HUMAN" 10 1409.7737 - 127406 5925 3 1409.773765 470.9318 Heterogeneous nuclear ribonucleoprotein U OS=Homo sapiens OX=9606 GN=HNRNPU PE=1 SV=6 6.23 1587.6 - 646311 - - - 0.0489 - 1.453 0.207 - 79.1 1 2 1 0.0001 11 0 0 0 - - - - - 1.9092 0.9998 221125_WJC_METTL3_EV_vs_WT_F09.05930.05930.2 7.22E-06 24-Oct K.EQTFSGGTSQDTK.A "sp|Q9Y2W1|TR150_HUMAN,tr|A0A3B3ITZ9|A0A3B3ITZ9_HUMAN" 2 1384.6107 4.47 127408 5930 2 1384.60943 693.3126 Thyroid hormone receptor-associated protein 3 OS=Homo sapiens OX=9606 GN=THRAP3 PE=1 SV=2 4.37 1588.3 - 139184 - - - -0.8833 - 1.731 0.573 - 281 1 2 0 -0.0012 13 0 0 0 9.61E+06 2.15E+06 - - - 4.681 0.9612 221125_WJC_METTL3_EV_vs_WT_F09.05937.05937.2 0.0602 20-Dec K.LLEQYKEESKK.A "sp|Q00839|HNRPU_HUMAN,tr|A0A1W2PQL0|A0A1W2PQL0_HUMAN,tr|A0A1W2PPL4|A0A1W2PPL4_HUMAN,tr|Q5RI18|Q5RI18_HUMAN,tr|A0A1W2PP35|A0A1W2PP35_HUMAN,tr|A0A1W2PPS1|A0A1W2PPS1_HUMAN,tr|A0A1W2PPH7|A0A1W2PPH7_HUMAN,tr|A0A1W2PQD4|A0A1W2PQD4_HUMAN,tr|A0A1W2PP34|A0A1W2PP34_HUMAN,tr|A0A1X7SBS1|A0A1X7SBS1_HUMAN" 10 1393.7453 0.99 127411 5937 2 1393.750886 697.8799 Heterogeneous nuclear ribonucleoprotein U OS=Homo sapiens OX=9606 GN=HNRNPU PE=1 SV=6 6.23 1589.2 - 618386 - - - 4.0108 - 1.698 0.387 - 184 1 2 1 0.0056 11 0 0 0 1.01E+08 1.02E+08 - - - 3.3299 0.8885 221125_WJC_METTL3_EV_vs_WT_F09.05942.05942.2 1.62E-05 Aug-32 L.VSGLNSSASEPAK[136.11]EPAK[136.11].K "sp|Q86U44|MTA70_HUMAN,tr|F5H6D8|F5H6D8_HUMAN,tr|H0YFV6|H0YFV6_HUMAN,tr|B4DTN4|B4DTN4_HUMAN" 4 1686.8759 0.001 127415 5942 2 1686.873555 844.4452 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 6.11 1589.9 - 117196 - - - -1.4073 - 1.771 0.586 - 142.3 1 1 1 -0.0024 17 0 0 0 0.00E+00 8.35E+06 - - - 4.7736 0.9996 221125_WJC_METTL3_EV_vs_WT_F09.05944.05944.3 4.66E-05 Aug-40 K.YKYPEGSDQER.Q "sp|Q08188|TGM3_HUMAN,tr|A0A494C0J7|A0A494C0J7_HUMAN" 2 1370.6103 1.09 127416 5944 3 1370.609768 457.8774 Protein-glutamine gamma-glutamyltransferase E OS=Homo sapiens OX=9606 GN=TGM3 PE=1 SV=4 4.68 1590.1 - 446593 - - - -0.3582 - 2.189 0.418 - 82.1 1 2 1 -0.0005 11 0 0 0 4.28E+07 3.93E+07 - - - 5.4258 1 221125_WJC_METTL3_EV_vs_WT_F09.05954.05954.2 4.52E-07 18/20 K.LLEQYK[136.11]EESK[136.11]K[136.11].A "sp|Q00839|HNRPU_HUMAN,tr|A0A1W2PQL0|A0A1W2PQL0_HUMAN,tr|A0A1W2PPL4|A0A1W2PPL4_HUMAN,tr|Q5RI18|Q5RI18_HUMAN,tr|A0A1W2PP35|A0A1W2PP35_HUMAN,tr|A0A1W2PPS1|A0A1W2PPS1_HUMAN,tr|A0A1W2PPH7|A0A1W2PPH7_HUMAN,tr|A0A1W2PQD4|A0A1W2PQD4_HUMAN,tr|A0A1W2PP34|A0A1W2PP34_HUMAN,tr|A0A1X7SBS1|A0A1X7SBS1_HUMAN" 10 1417.7879 0.99 127421 5954 2 1417.786777 709.9012 Heterogeneous nuclear ribonucleoprotein U OS=Homo sapiens OX=9606 GN=HNRNPU PE=1 SV=6 6.23 1591.5 - 863440 - - - -0.7893 - 3.237 0.558 - 1101.6 1 2 1 -0.0011 11 0 0 0 1.01E+08 1.02E+08 - - - 6.3397 0.9422 221125_WJC_METTL3_EV_vs_WT_F09.05960.05960.3 0.00751 Oct-44 Y.R[166.11]ADTQTYQPYNK[136.11].D sp|P84090|ERH_HUMAN 1 1501.728 3.85 127424 5960 3 1501.726369 501.5833 Enhancer of rudimentary homolog OS=Homo sapiens OX=9606 GN=ERH PE=1 SV=1 8.5 1592.3 - 198229 - - - -1.1034 - 1.638 0.344 - 128.9 1 1 0 -0.0017 12 0 0 0 5.28E+07 1.37E+07 - - - 3.7426 0.9981 221125_WJC_METTL3_EV_vs_WT_F09.05965.05965.3 0.000131 Jul-44 R.NIDEHANEDVER.M sp|P61026|RAB10_HUMAN 1 1439.6277 12.89 127427 5965 3 1439.620722 480.8832 Ras-related protein Rab-10 OS=Homo sapiens OX=9606 GN=RAB10 PE=1 SV=1 4.17 1592.9 - 229291 - - - -4.8471 - 1.832 0.424 - 64.1 1 2 0 -0.007 12 0 0 0 1.44E+07 1.11E+06 - - - 4.9433 0.9932 221125_WJC_METTL3_EV_vs_WT_F09.05995.05995.3 0.622 Oct-48 K.IQDKEGIPPDQQR.L "sp|P62979|RS27A_HUMAN,sp|P0CG48|UBC_HUMAN,sp|P0CG48|UBC_HUMAN,sp|P0CG48|UBC_HUMAN,sp|P0CG48|UBC_HUMAN,sp|P0CG48|UBC_HUMAN,sp|P0CG48|UBC_HUMAN,sp|P0CG48|UBC_HUMAN,sp|P0CG48|UBC_HUMAN,sp|P0CG48|UBC_HUMAN,sp|P0CG47|UBB_HUMAN,sp|P0CG47|UBB_HUMAN,sp|P0CG47|UBB_HUMAN,sp|P62987|RL40_HUMAN,tr|F5H388|F5H388_HUMAN,tr|F5H388|F5H388_HUMAN,tr|F5GYU3|F5GYU3_HUMAN,tr|F5GYU3|F5GYU3_HUMAN,tr|B4DV12|B4DV12_HUMAN,tr|B4DV12|B4DV12_HUMAN,tr|J3QSA3|J3QSA3_HUMAN,tr|Q5PY61|Q5PY61_HUMAN,tr|Q5PY61|Q5PY61_HUMAN,tr|Q5PY61|Q5PY61_HUMAN,tr|F5H2Z3|F5H2Z3_HUMAN,tr|F5H2Z3|F5H2Z3_HUMAN,tr|M0R2S1|M0R2S1_HUMAN,tr|J3QS39|J3QS39_HUMAN,tr|J3QTR3|J3QTR3_HUMAN,tr|Q96C32|Q96C32_HUMAN,tr|Q96C32|Q96C32_HUMAN,tr|Q96C32|Q96C32_HUMAN,tr|Q96C32|Q96C32_HUMAN,tr|M0R1V7|M0R1V7_HUMAN,tr|F5H747|F5H747_HUMAN,tr|F5H747|F5H747_HUMAN,tr|F5GXK7|F5GXK7_HUMAN,tr|F5GXK7|F5GXK7_HUMAN,tr|M0R1M6|M0R1M6_HUMAN,tr|F5H6Q2|F5H6Q2_HUMAN,tr|F5H6Q2|F5H6Q2_HUMAN,tr|F5GZ39|F5GZ39_HUMAN,tr|J3QKN0|J3QKN0_HUMAN,tr|J3QKN0|J3QKN0_HUMAN,tr|F5H265|F5H265_HUMAN,tr|F5H265|F5H265_HUMAN,tr|A0A2R8Y422|A0A2R8Y422_HUMAN" 47 1522.774 0.66 127444 5995 3 1522.771115 508.5986 Ubiquitin-40S ribosomal protein S27a OS=Homo sapiens OX=9606 GN=RPS27A PE=1 SV=2 4.56 1596.8 - 434797 - - - -1.8749 - 2.003 0.266 - 146.8 1 2 1 -0.0029 13 0 0 0 1.29E+08 1.96E+08 - - - 3.3882 0.9999 221125_WJC_METTL3_EV_vs_WT_F09.05998.05998.3 0.000153 Nov-52 K.FGQGIHHAAGQVGK.E sp|Q6UWP8|SBSN_HUMAN 1 1405.7215 999 127445 5998 3 1405.71915 469.5811 Suprabasin OS=Homo sapiens OX=9606 GN=SBSN PE=1 SV=2 8.76 1597.2 - 1.24E+06 - - - -1.6582 - 2.251 0.4 - 82 1 2 0 -0.0023 14 0 0 0 7.09E+07 0.00E+00 - - - 5.1552 0.9443 221125_WJC_METTL3_EV_vs_WT_F09.06000.06000.2 0.0476 26-May K.EK[136.11]EEVAEEAQSGGD.- sp|O76070|SYUG_HUMAN 1 1484.6358 2.99 127446 6000 2 1484.634599 743.3252 Gamma-synuclein OS=Homo sapiens OX=9606 GN=SNCG PE=1 SV=2 4 1597.4 - 85282.9 - - - -0.8164 - 1.046 0.27 - 83.5 1 2 1 -0.0012 14 0 0 0 3.97E+07 1.33E+07 - - - 1.1477 0.9999 221125_WJC_METTL3_EV_vs_WT_F09.06009.06009.3 6.22E-05 Nov-56 K.C[160.03]IGKPGGSLDNSEQK.C "sp|Q9Y5L4|TIM13_HUMAN,tr|K7EIT2|K7EIT2_HUMAN" 2 1588.7515 1.76 127452 6009 3 1588.751344 530.5911 Mitochondrial import inner membrane translocase subunit Tim13 OS=Homo sapiens OX=9606 GN=TIMM13 PE=1 SV=1 6.06 1598.4 - 368138 - - - -0.1108 - 2.077 0.474 - 119.1 1 2 0 -0.0002 15 0 0 0 8.22E+07 4.68E+07 - - - 5.7318 0.9993 221125_WJC_METTL3_EV_vs_WT_F09.06011.06011.3 0.0383 Sep-36 R.KESEFDDEPK.F "sp|Q9Y2W1|TR150_HUMAN,tr|A0A3B3ITZ9|A0A3B3ITZ9_HUMAN" 2 1222.5354 3.1 127453 6011 3 1222.533877 408.5191 Thyroid hormone receptor-associated protein 3 OS=Homo sapiens OX=9606 GN=THRAP3 PE=1 SV=2 4.18 1598.7 - 339647 - - - -1.2155 - 1.673 0.32 - 120.9 1 2 0 -0.0015 10 0 0 0 2.58E+07 8.33E+06 - - - 3.6102 0.9998 221125_WJC_METTL3_EV_vs_WT_F09.06012.06012.3 0.000459 Sep-56 K.C[160.03]IGK[136.11]PGGSLDNSEQK[136.11].C "sp|Q9Y5L4|TIM13_HUMAN,tr|K7EIT2|K7EIT2_HUMAN" 2 1604.7799 1.75 127454 6012 3 1604.779706 535.9339 Mitochondrial import inner membrane translocase subunit Tim13 OS=Homo sapiens OX=9606 GN=TIMM13 PE=1 SV=1 6.06 1598.8 - 323794 - - - -0.1334 - 1.651 0.437 - 50.3 1 2 0 -0.0002 15 0 0 0 8.19E+07 4.68E+07 - - - 4.7203 0.9993 221125_WJC_METTL3_EV_vs_WT_F09.06018.06018.3 0.000733 13/48 K.IQDK[136.11]EGIPPDQQR[166.11].L "sp|P62979|RS27A_HUMAN,sp|P0CG48|UBC_HUMAN,sp|P0CG48|UBC_HUMAN,sp|P0CG48|UBC_HUMAN,sp|P0CG48|UBC_HUMAN,sp|P0CG48|UBC_HUMAN,sp|P0CG48|UBC_HUMAN,sp|P0CG48|UBC_HUMAN,sp|P0CG48|UBC_HUMAN,sp|P0CG48|UBC_HUMAN,sp|P0CG47|UBB_HUMAN,sp|P0CG47|UBB_HUMAN,sp|P0CG47|UBB_HUMAN,sp|P62987|RL40_HUMAN,tr|F5H388|F5H388_HUMAN,tr|F5H388|F5H388_HUMAN,tr|F5GYU3|F5GYU3_HUMAN,tr|F5GYU3|F5GYU3_HUMAN,tr|B4DV12|B4DV12_HUMAN,tr|B4DV12|B4DV12_HUMAN,tr|J3QSA3|J3QSA3_HUMAN,tr|Q5PY61|Q5PY61_HUMAN,tr|Q5PY61|Q5PY61_HUMAN,tr|Q5PY61|Q5PY61_HUMAN,tr|F5H2Z3|F5H2Z3_HUMAN,tr|F5H2Z3|F5H2Z3_HUMAN,tr|M0R2S1|M0R2S1_HUMAN,tr|J3QS39|J3QS39_HUMAN,tr|J3QTR3|J3QTR3_HUMAN,tr|Q96C32|Q96C32_HUMAN,tr|Q96C32|Q96C32_HUMAN,tr|Q96C32|Q96C32_HUMAN,tr|Q96C32|Q96C32_HUMAN,tr|M0R1V7|M0R1V7_HUMAN,tr|F5H747|F5H747_HUMAN,tr|F5H747|F5H747_HUMAN,tr|F5GXK7|F5GXK7_HUMAN,tr|F5GXK7|F5GXK7_HUMAN,tr|M0R1M6|M0R1M6_HUMAN,tr|F5H6Q2|F5H6Q2_HUMAN,tr|F5H6Q2|F5H6Q2_HUMAN,tr|F5GZ39|F5GZ39_HUMAN,tr|J3QKN0|J3QKN0_HUMAN,tr|J3QKN0|J3QKN0_HUMAN,tr|F5H265|F5H265_HUMAN,tr|F5H265|F5H265_HUMAN,tr|A0A2R8Y422|A0A2R8Y422_HUMAN" 47 1540.7964 0.66 127458 6018 3 1540.795869 514.6061 Ubiquitin-40S ribosomal protein S27a OS=Homo sapiens OX=9606 GN=RPS27A PE=1 SV=2 4.56 1599.6 - 623764 - - - -0.3706 - 2.211 0.366 - 263.9 1 2 1 -0.0006 13 0 0 0 1.39E+08 2.10E+08 - - - 4.7716 0.9991 221125_WJC_METTL3_EV_vs_WT_F09.06023.06023.3 0.000647 Aug-40 K.ADDPYAHLSK[136.11]K[136.11].E "sp|Q8NE71|ABCF1_HUMAN,tr|Q5STZ8|Q5STZ8_HUMAN,tr|A0A0G2JJB9|A0A0G2JJB9_HUMAN" 3 1259.6481 0.61 127460 6023 3 1259.64539 420.89 ATP-binding cassette sub-family F member 1 OS=Homo sapiens OX=9606 GN=ABCF1 PE=1 SV=2 6.79 1600.2 - 180837 - - - -2.1522 - 1.711 0.346 - 78.6 1 2 0 -0.0027 11 0 0 0 6.77E+06 1.12E+07 - - - 3.9226 0.9995 221125_WJC_METTL3_EV_vs_WT_F09.06031.06031.2 0.00166 22-May R.QQIC[160.03]NQQPPC[160.03]SR[166.11].L "sp|Q7Z2W4|ZCCHV_HUMAN,tr|C9J6P4|C9J6P4_HUMAN,tr|A0A7P0T8C6|A0A7P0T8C6_HUMAN" 3 1524.6801 1.03 127463 6031 2 1524.681317 763.3473 Zinc finger CCCH-type antiviral protein 1 OS=Homo sapiens OX=9606 GN=ZC3HAV1 PE=1 SV=3 8.07 1601.3 - 142456 - - - 0.7975 - 1.307 0.479 - 69.1 1 2 0 0.0012 12 0 0 0 1.58E+07 1.53E+07 - - - 3.283 0.9114 221125_WJC_METTL3_EV_vs_WT_F09.06038.06038.2 0.079 20-May K.SESPKEPEQLR.K "sp|P09651|ROA1_HUMAN,tr|F8W646|F8W646_HUMAN,tr|A0A7I2V3R8|A0A7I2V3R8_HUMAN,tr|F8VTQ5|F8VTQ5_HUMAN,tr|A0A7I2YQ85|A0A7I2YQ85_HUMAN,tr|F8W6I7|F8W6I7_HUMAN,tr|A0A7I2V2L6|A0A7I2V2L6_HUMAN,tr|A0A7I2V3W0|A0A7I2V3W0_HUMAN" 8 1298.6466 1.18 127469 6038 2 1298.645231 650.3306 Heterogeneous nuclear ribonucleoprotein A1 OS=Homo sapiens OX=9606 GN=HNRNPA1 PE=1 SV=5 4.78 1602.1 - 88262.4 - - - -1.0881 - 1.131 0.203 - 100.7 1 2 1 -0.0014 11 0 0 0 1.66E+07 1.41E+07 - - - 0.8729 0.9994 221125_WJC_METTL3_EV_vs_WT_F09.06041.06041.3 0.000255 Dec-40 K.LLEQYK[136.11]EESK[136.11]K[136.11].A "sp|Q00839|HNRPU_HUMAN,tr|A0A1W2PQL0|A0A1W2PQL0_HUMAN,tr|A0A1W2PPL4|A0A1W2PPL4_HUMAN,tr|Q5RI18|Q5RI18_HUMAN,tr|A0A1W2PP35|A0A1W2PP35_HUMAN,tr|A0A1W2PPS1|A0A1W2PPS1_HUMAN,tr|A0A1W2PPH7|A0A1W2PPH7_HUMAN,tr|A0A1W2PQD4|A0A1W2PQD4_HUMAN,tr|A0A1W2PP34|A0A1W2PP34_HUMAN,tr|A0A1X7SBS1|A0A1X7SBS1_HUMAN" 10 1417.7879 0.94 127470 6041 3 1417.785385 473.6032 Heterogeneous nuclear ribonucleoprotein U OS=Homo sapiens OX=9606 GN=HNRNPU PE=1 SV=6 6.23 1602.5 - 2.75E+07 - - - -1.7711 - 2.374 0.385 - 207.6 1 2 1 -0.0025 11 0 0 0 2.63E+09 2.78E+09 - - - 5.2878 0.9979 221125_WJC_METTL3_EV_vs_WT_F09.06042.06042.3 0.00848 Nov-40 K.SESPKEPEQLR.K "sp|P09651|ROA1_HUMAN,tr|F8W646|F8W646_HUMAN,tr|A0A7I2V3R8|A0A7I2V3R8_HUMAN,tr|F8VTQ5|F8VTQ5_HUMAN,tr|A0A7I2YQ85|A0A7I2YQ85_HUMAN,tr|F8W6I7|F8W6I7_HUMAN,tr|A0A7I2V2L6|A0A7I2V2L6_HUMAN,tr|A0A7I2V3W0|A0A7I2V3W0_HUMAN" 8 1298.6466 1.45 127471 6042 3 1298.645931 433.8895 Heterogeneous nuclear ribonucleoprotein A1 OS=Homo sapiens OX=9606 GN=HNRNPA1 PE=1 SV=5 4.78 1602.6 - 1.49E+06 - - - -0.549 - 2.246 0.273 - 210 1 2 1 -0.0007 11 0 0 0 2.83E+08 1.95E+08 - - - 3.8821 0.9843 221125_WJC_METTL3_EV_vs_WT_F09.06048.06048.3 0.393 Jul-40 K.LLEQYKEESKK.A "sp|Q00839|HNRPU_HUMAN,tr|A0A1W2PQL0|A0A1W2PQL0_HUMAN,tr|A0A1W2PPL4|A0A1W2PPL4_HUMAN,tr|Q5RI18|Q5RI18_HUMAN,tr|A0A1W2PP35|A0A1W2PP35_HUMAN,tr|A0A1W2PPS1|A0A1W2PPS1_HUMAN,tr|A0A1W2PPH7|A0A1W2PPH7_HUMAN,tr|A0A1W2PQD4|A0A1W2PQD4_HUMAN,tr|A0A1W2PP34|A0A1W2PP34_HUMAN,tr|A0A1X7SBS1|A0A1X7SBS1_HUMAN" 10 1393.7453 0.94 127474 6048 3 1393.744408 465.589 Heterogeneous nuclear ribonucleoprotein U OS=Homo sapiens OX=9606 GN=HNRNPU PE=1 SV=6 6.23 1603.3 - 2.73E+07 - - - -0.6371 - 1.689 0.219 - 60.4 1 2 1 -0.0009 11 0 0 0 2.65E+09 2.81E+09 - - - 2.4704 0.9933 221125_WJC_METTL3_EV_vs_WT_F09.06063.06063.2 0.159 18-May R.KESEFDDEPK.F "sp|Q9Y2W1|TR150_HUMAN,tr|A0A3B3ITZ9|A0A3B3ITZ9_HUMAN" 2 1222.5354 39.81 127483 6063 2 1222.537616 612.275 Thyroid hormone receptor-associated protein 3 OS=Homo sapiens OX=9606 GN=THRAP3 PE=1 SV=2 4.18 1605.1 - 98579.8 - - - 1.8429 - 1.152 0.27 - 104.2 1 2 0 0.0023 10 0 0 0 5.25E+06 1.32E+05 - - - 1.4295 0.9998 221125_WJC_METTL3_EV_vs_WT_F09.06065.06065.3 0.0018 Nov-52 K.KGPGEVAGTVTGQK[136.11].R "sp|Q86U44|MTA70_HUMAN,tr|F5H6D8|F5H6D8_HUMAN,tr|H0YFV6|H0YFV6_HUMAN,tr|B4DTN4|B4DTN4_HUMAN" 4 1335.7238 - 127484 6065 3 1335.723998 446.2485 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 8.59 1605.4 - 3.45E+06 - - - 0.164 - 2.624 0.315 - 200.8 1 2 0 0.0002 14 0 0 0 - - - - - 4.6156 0.9992 221125_WJC_METTL3_EV_vs_WT_F09.06069.06069.3 0.00142 Nov-40 K.LLEQYKEESKK.A "sp|Q00839|HNRPU_HUMAN,tr|A0A1W2PQL0|A0A1W2PQL0_HUMAN,tr|A0A1W2PPL4|A0A1W2PPL4_HUMAN,tr|Q5RI18|Q5RI18_HUMAN,tr|A0A1W2PP35|A0A1W2PP35_HUMAN,tr|A0A1W2PPS1|A0A1W2PPS1_HUMAN,tr|A0A1W2PPH7|A0A1W2PPH7_HUMAN,tr|A0A1W2PQD4|A0A1W2PQD4_HUMAN,tr|A0A1W2PP34|A0A1W2PP34_HUMAN,tr|A0A1X7SBS1|A0A1X7SBS1_HUMAN" 10 1393.7453 0.94 127487 6069 3 1393.743205 465.589 Heterogeneous nuclear ribonucleoprotein U OS=Homo sapiens OX=9606 GN=HNRNPU PE=1 SV=6 6.23 1605.9 - 1.52E+07 - - - -1.5003 - 2.162 0.38 - 162.4 1 2 1 -0.0021 11 0 0 0 2.65E+09 2.81E+09 - - - 4.9664 1 221125_WJC_METTL3_EV_vs_WT_F09.06082.06082.3 1.22E-06 15/52 K.K[136.11]GPGEVAGTVTGQK[136.11].R "sp|Q86U44|MTA70_HUMAN,tr|F5H6D8|F5H6D8_HUMAN,tr|H0YFV6|H0YFV6_HUMAN,tr|B4DTN4|B4DTN4_HUMAN" 4 1343.738 0 127492 6082 3 1343.73823 448.9199 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 8.59 1607.6 - 1.20E+08 - - - 0.1868 - 3.066 0.56 - 429.5 1 2 0 0.0003 14 0 0 0 3.92E+07 6.03E+11 - - - 7.7608 0.9999 221125_WJC_METTL3_EV_vs_WT_F09.06088.06088.2 4.08E-06 Jul-34 R.SSGAASSAPGGGDGAEYK.T "sp|Q96T37|RBM15_HUMAN,tr|A0A494C001|A0A494C001_HUMAN,tr|A0A499FJY3|A0A499FJY3_HUMAN,tr|A0A087WWP4|A0A087WWP4_HUMAN" 4 1567.675 1.28 127496 6088 2 1567.673914 784.8448 RNA-binding protein 15 OS=Homo sapiens OX=9606 GN=RBM15 PE=1 SV=2 4.37 1608.2 - 240654 - - - -0.7208 - 1.89 0.6 - 66.2 1 2 0 -0.0011 18 0 0 0 6.60E+07 5.17E+07 - - - 5.0373 0.9999 221125_WJC_METTL3_EV_vs_WT_F09.06092.06092.2 1.58E-05 22-Oct R.QQIC[160.03]NQQPPC[160.03]SR.L "sp|Q7Z2W4|ZCCHV_HUMAN,tr|C9J6P4|C9J6P4_HUMAN,tr|A0A7P0T8C6|A0A7P0T8C6_HUMAN" 3 1514.6718 1.08 127498 6092 2 1514.67145 758.3432 Zinc finger CCCH-type antiviral protein 1 OS=Homo sapiens OX=9606 GN=ZC3HAV1 PE=1 SV=3 8.07 1608.8 - 460489 - - - -0.2515 - 1.969 0.592 - 254.8 1 2 0 -0.0004 12 0 0 0 1.55E+07 1.44E+07 - - - 5.1961 0.9999 221125_WJC_METTL3_EV_vs_WT_F09.06093.06093.2 1.75E-05 Aug-34 R.SSGAASSAPGGGDGAEYK[136.11].T "sp|Q96T37|RBM15_HUMAN,tr|A0A494C001|A0A494C001_HUMAN,tr|A0A499FJY3|A0A499FJY3_HUMAN,tr|A0A087WWP4|A0A087WWP4_HUMAN" 4 1575.6892 1.28 127499 6093 2 1575.687933 788.8519 RNA-binding protein 15 OS=Homo sapiens OX=9606 GN=RBM15 PE=1 SV=2 4.37 1608.9 - 249260 - - - -0.832 - 1.773 0.619 - 88.5 1 2 0 -0.0013 18 0 0 0 6.60E+07 5.17E+07 - - - 5.0205 1 221125_WJC_METTL3_EV_vs_WT_F09.06095.06095.2 1.10E-06 18/26 K.K[136.11]GPGEVAGTVTGQK[136.11].R "sp|Q86U44|MTA70_HUMAN,tr|F5H6D8|F5H6D8_HUMAN,tr|H0YFV6|H0YFV6_HUMAN,tr|B4DTN4|B4DTN4_HUMAN" 4 1343.738 0 127500 6095 2 1343.735949 672.8763 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 8.59 1609.1 - 3.10E+07 - - - -1.5107 - 3.361 0.573 - 817.1 1 2 0 -0.002 14 0 0 0 8.54E+08 2.86E+11 - - - 6.3146 0.9781 221125_WJC_METTL3_EV_vs_WT_F09.06105.06105.3 3.13E-07 18/64 L.VSGLNSSASEPAK[136.11]EPAK[136.11].K "sp|Q86U44|MTA70_HUMAN,tr|F5H6D8|F5H6D8_HUMAN,tr|H0YFV6|H0YFV6_HUMAN,tr|B4DTN4|B4DTN4_HUMAN" 4 1686.8759 0 127505 6105 3 1686.870841 563.2993 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 6.11 1610.5 - 2.54E+06 - - - -3.0162 - 3.315 0.566 - 422.2 1 1 1 -0.0051 17 0 0 0 3.67E+05 3.53E+08 - - - 7.8766 1 221125_WJC_METTL3_EV_vs_WT_F09.06109.06109.2 0.00111 17/26 K.KGPGEVAGTVTGQK[136.11].R "sp|Q86U44|MTA70_HUMAN,tr|F5H6D8|F5H6D8_HUMAN,tr|H0YFV6|H0YFV6_HUMAN,tr|B4DTN4|B4DTN4_HUMAN" 4 1335.7238 - 127508 6109 2 1335.722034 668.8692 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 8.59 1610.9 - 1.53E+06 - - - -1.3064 - 3.354 0.53 - 535.1 1 2 0 -0.0017 14 0 0 0 - - - - - 5.9919 0.9582 221125_WJC_METTL3_EV_vs_WT_F09.06111.06111.3 2.38 Aug-52 K.TGENLRPQNGSTYK.K sp|Q86V15|CASZ1_HUMAN 1 1563.7641 0.94 127509 6111 3 1563.762388 522.262 Zinc finger protein castor homolog 1 OS=Homo sapiens OX=9606 GN=CASZ1 PE=1 SV=4 8.26 1611.2 - 329921 - - - -1.1165 - 1.579 0.111 - 48.5 1 2 0 -0.0017 14 0 0 0 2.16E+07 2.30E+07 - - - 0.991 0.9663 221125_WJC_METTL3_EV_vs_WT_F09.06115.06115.2 0.0029 24-Jul K.ASSTSLTSTQPTK.T "sp|P35658|NU214_HUMAN,tr|A0A0A0MSW3|A0A0A0MSW3_HUMAN,tr|E9PKD2|E9PKD2_HUMAN,tr|B7ZAV2|B7ZAV2_HUMAN,tr|A0A494C1F2|A0A494C1F2_HUMAN,tr|H0Y837|H0Y837_HUMAN" 6 1307.6569 0.87 127511 6115 2 1307.651756 654.8357 Nuclear pore complex protein Nup214 OS=Homo sapiens OX=9606 GN=NUP214 PE=1 SV=2 8.8 1611.7 - 113075 - - - -3.9146 - 1.429 0.178 - 144.3 1 2 0 -0.0051 13 0 0 0 7.09E+06 8.12E+06 - - - 1.2703 0.9957 221125_WJC_METTL3_EV_vs_WT_F09.06116.06116.2 0.0297 26-Jun K.KGPGEVAGTVTGQK.R "sp|Q86U44|MTA70_HUMAN,tr|F5H6D8|F5H6D8_HUMAN,tr|H0YFV6|H0YFV6_HUMAN,tr|B4DTN4|B4DTN4_HUMAN" 4 1327.7096 0 127512 6116 2 1327.709835 664.8621 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 8.59 1611.8 - 140746 - - - 0.1928 - 1.18 0.24 - 73.6 1 2 0 0.0003 14 0 0 0 6.08E+08 2.01E+11 - - - 1.2289 1 221125_WJC_METTL3_EV_vs_WT_F09.06122.06122.2 9.49E-07 15/24 K.GPGEVAGTVTGQK[136.11].R "sp|Q86U44|MTA70_HUMAN,tr|F5H6D8|F5H6D8_HUMAN,tr|H0YFV6|H0YFV6_HUMAN,tr|B4DTN4|B4DTN4_HUMAN" 4 1207.6288 0.001 127514 6122 2 1207.627441 604.8217 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 6 1612.6 - 127219 - - - -1.1386 - 2.862 0.604 - 1039 1 2 0 -0.0014 13 0 0 0 0.00E+00 1.35E+08 - - - 6.2005 0.9936 221125_WJC_METTL3_EV_vs_WT_F09.06156.06156.3 0.087 Jul-36 R.K[136.11]IQGIEEYK[136.11]K[136.11].G "sp|Q9Y6G9|DC1L1_HUMAN,tr|C9JLW1|C9JLW1_HUMAN,tr|C9JGM7|C9JGM7_HUMAN" 3 1258.7347 0.71 127526 6156 3 1258.732727 420.5855 Cytoplasmic dynein 1 light intermediate chain 1 OS=Homo sapiens OX=9606 GN=DYNC1LI1 PE=1 SV=3 8.43 1617.3 - 308982 - - - -1.5976 - 1.611 0.211 - 68.5 1 2 0 -0.002 10 0 0 0 1.94E+07 2.72E+07 - - - 2.2845 0.9998 221125_WJC_METTL3_EV_vs_WT_F09.06171.06171.2 0.000223 24-Oct R.FSSSSGYGGGSSR.V sp|P35527|K1C9_HUMAN 1 1234.5214 999 127531 6171 2 1234.519696 618.268 "Keratin, type I cytoskeletal 9 OS=Homo sapiens OX=9606 GN=KRT9 PE=1 SV=3" 8.75 1619.4 - 659359 - - - -1.4159 - 2.073 0.567 - 286.2 1 2 0 -0.0017 13 0 0 0 1.91E+08 0.00E+00 - - - 5.0993 0.9679 221125_WJC_METTL3_EV_vs_WT_F09.06180.06180.2 0.0934 16-Sep E.VAGTVTGQK[136.11].R "sp|Q86U44|MTA70_HUMAN,tr|F5H6D8|F5H6D8_HUMAN,tr|H0YFV6|H0YFV6_HUMAN,tr|B4DTN4|B4DTN4_HUMAN" 4 867.4905 0.02 127533 6180 2 867.489208 434.7525 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 8.72 1620.7 - 687441 - - - -1.5251 - 1.75 0.371 - 192.7 1 1 0 -0.0013 9 0 0 0 1.45E+07 7.51E+08 - - - 3.3998 0.9999 221125_WJC_METTL3_EV_vs_WT_F09.06196.06196.3 9.98E-07 16/44 R.HQVIQTVHPVEK[136.11].K "sp|Q9H2P0|ADNP_HUMAN,tr|A0A2R8Y6X0|A0A2R8Y6X0_HUMAN,tr|A0A669KBJ7|A0A669KBJ7_HUMAN" 3 1421.787 1.15 127537 6196 3 1421.781967 474.9363 Activity-dependent neuroprotector homeobox protein OS=Homo sapiens OX=9606 GN=ADNP PE=1 SV=1 6.92 1623 - 1.11E+06 - - - -3.5737 - 2.913 0.548 - 287.3 1 2 0 -0.0051 12 0 0 0 6.54E+07 5.66E+07 - - - 7.6119 1 221125_WJC_METTL3_EV_vs_WT_F09.06202.06202.3 1.60E-05 17/44 R.HQVIQTVHPVEK.K "sp|Q9H2P0|ADNP_HUMAN,tr|A0A2R8Y6X0|A0A2R8Y6X0_HUMAN,tr|A0A669KBJ7|A0A669KBJ7_HUMAN" 3 1413.7728 1.14 127538 6202 3 1413.769151 472.2649 Activity-dependent neuroprotector homeobox protein OS=Homo sapiens OX=9606 GN=ADNP PE=1 SV=1 6.92 1623.9 - 744010 - - - -2.615 - 3.259 0.593 - 341.5 1 2 0 -0.0037 12 0 0 0 6.42E+07 5.65E+07 - - - 8.4251 0.9981 221125_WJC_METTL3_EV_vs_WT_F09.06213.06213.3 0.00258 Nov-48 K.K[136.11]EAQELSQNSAIK[136.11].Q sp|Q9NR30|DDX21_HUMAN 1 1460.7806 1.03 127541 6213 3 1460.773572 487.9341 Nucleolar RNA helicase 2 OS=Homo sapiens OX=9606 GN=DDX21 PE=1 SV=5 6.14 1625.5 - 1.09E+06 - - - -4.792 - 2.482 0.351 - 189.1 1 2 0 -0.007 13 0 0 0 5.84E+07 5.68E+07 - - - 4.9161 1 221125_WJC_METTL3_EV_vs_WT_F09.06242.06242.3 1.42E-07 13/48 K.VQDQDLPNTPHSK.A sp|Q08554|DSC1_HUMAN 1 1477.7161 189.74 127548 6242 3 1477.71457 493.5793 Desmocollin-1 OS=Homo sapiens OX=9606 GN=DSC1 PE=1 SV=2 5.21 1629.7 - 1.06E+06 - - - -1.0496 - 2.596 0.536 - 242.4 1 2 0 -0.0016 13 0 0 0 6.13E+08 3.23E+06 - - - 7.1019 0.9204 221125_WJC_METTL3_EV_vs_WT_F09.06270.06270.2 0.0734 14-Aug V.AGTVTGQK[136.11].R "sp|Q86U44|MTA70_HUMAN,tr|F5H6D8|F5H6D8_HUMAN,tr|H0YFV6|H0YFV6_HUMAN,tr|B4DTN4|B4DTN4_HUMAN" 4 768.4221 0.17 127554 6270 2 768.420694 385.2183 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 8.8 1633.9 - 1.22E+07 - - - -1.8531 - 1.956 0.214 - 319.4 1 1 0 -0.0014 8 0 0 0 4.60E+08 2.74E+09 - - - 2.6446 1 221125_WJC_METTL3_EV_vs_WT_F09.06280.06280.3 8.42E-15 19/60 K.AISVHSTPEGC[160.03]SSAC[160.03]K.M sp|Q9NZI8|IF2B1_HUMAN 1 1689.7451 2.1 127558 6280 3 1689.741203 564.2556 Insulin-like growth factor 2 mRNA-binding protein 1 OS=Homo sapiens OX=9606 GN=IGF2BP1 PE=1 SV=2 6.77 1635.1 - 2.37E+06 - - - -2.2796 - 3.641 0.74 - 346.5 1 2 0 -0.0039 16 0 0 0 1.05E+08 4.99E+07 - - - 10.105 1 221125_WJC_METTL3_EV_vs_WT_F09.06283.06283.3 2.61E-06 13/52 K.KGPGEVAGTVTGQK[136.11].R "sp|Q86U44|MTA70_HUMAN,tr|F5H6D8|F5H6D8_HUMAN,tr|H0YFV6|H0YFV6_HUMAN,tr|B4DTN4|B4DTN4_HUMAN" 4 1335.7238 - 127559 6283 3 1335.722529 446.2485 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 8.59 1635.5 - 1.02E+08 - - - -0.9358 - 2.802 0.452 - 274.4 1 2 0 -0.0013 14 0 0 0 - - - - - 6.3172 0.9927 221125_WJC_METTL3_EV_vs_WT_F09.06294.06294.3 0.0114 Nov-44 R.VNAVPR[166.11]PIPEK[136.11]K[136.11].W sp|Q9HD45|TM9S3_HUMAN 1 1372.8401 0.001 127564 6294 3 1372.834497 458.6206 Transmembrane 9 superfamily member 3 OS=Homo sapiens OX=9606 GN=TM9SF3 PE=1 SV=2 9.99 1636.9 - 4.06E+06 - - - -4.074 - 1.792 0.29 - 135.3 1 2 0 -0.0056 12 0 0 0 0.00E+00 9.86E+07 - - - 3.3886 1 221125_WJC_METTL3_EV_vs_WT_F09.06300.06300.3 2.38E-06 16/52 K.K[136.11]GPGEVAGTVTGQK[136.11].R "sp|Q86U44|MTA70_HUMAN,tr|F5H6D8|F5H6D8_HUMAN,tr|H0YFV6|H0YFV6_HUMAN,tr|B4DTN4|B4DTN4_HUMAN" 4 1343.738 0 127565 6300 3 1343.737446 448.9199 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 8.59 1637.8 - 3.14E+09 - - - -0.3967 - 3.145 0.51 - 429.9 1 2 0 -0.0005 14 0 0 0 3.92E+07 6.03E+11 - - - 7.2709 1 221125_WJC_METTL3_EV_vs_WT_F09.06301.06301.3 6.54E-05 20/60 R.ETGTEHSPGVQPADVK.E "sp|Q9H7C9|AAMDC_HUMAN,tr|K4DI89|K4DI89_HUMAN,tr|E9PLK9|E9PLK9_HUMAN,tr|E9PNP3|E9PNP3_HUMAN,tr|E9PJP1|E9PJP1_HUMAN" 5 1650.7849 1.93 127566 6301 3 1650.782368 551.2689 Mth938 domain-containing protein OS=Homo sapiens OX=9606 GN=AAMDC PE=1 SV=1 4.65 1637.9 - 4.38E+06 - - - -1.5514 - 2.569 0.506 - 386.1 1 2 0 -0.0026 16 0 0 0 1.58E+09 8.21E+08 - - - 6.6016 1 221125_WJC_METTL3_EV_vs_WT_F09.06310.06310.3 1.09E-05 20/60 R.ETGTEHSPGVQPADVK[136.11].E "sp|Q9H7C9|AAMDC_HUMAN,tr|K4DI89|K4DI89_HUMAN,tr|E9PLK9|E9PLK9_HUMAN,tr|E9PNP3|E9PNP3_HUMAN,tr|E9PJP1|E9PJP1_HUMAN" 5 1658.7991 1.93 127571 6310 3 1658.797444 553.9403 Mth938 domain-containing protein OS=Homo sapiens OX=9606 GN=AAMDC PE=1 SV=1 4.65 1638.8 - 5.94E+06 - - - -1.0158 - 2.608 0.528 - 362.4 1 2 0 -0.0017 16 0 0 0 1.58E+09 8.21E+08 - - - 6.8858 1 221125_WJC_METTL3_EV_vs_WT_F09.06314.06314.2 3.32E-07 20/26 K.K[136.11]GPGEVAGTVTGQK[136.11].R "sp|Q86U44|MTA70_HUMAN,tr|F5H6D8|F5H6D8_HUMAN,tr|H0YFV6|H0YFV6_HUMAN,tr|B4DTN4|B4DTN4_HUMAN" 4 1343.738 0 127572 6314 2 1343.735544 672.8763 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 8.59 1639.4 - 1.56E+09 - - - -1.8121 - 3.665 0.599 - 1156.9 1 2 0 -0.0024 14 0 0 0 8.53E+08 2.85E+11 - - - 6.7238 1 221125_WJC_METTL3_EV_vs_WT_F09.06327.06327.2 6.11E-05 19/26 K.KGPGEVAGTVTGQK[136.11].R "sp|Q86U44|MTA70_HUMAN,tr|F5H6D8|F5H6D8_HUMAN,tr|H0YFV6|H0YFV6_HUMAN,tr|B4DTN4|B4DTN4_HUMAN" 4 1335.7238 - 127576 6327 2 1335.72201 668.8692 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 8.59 1641.2 - 5.85E+07 - - - -1.3244 - 3.37 0.539 - 675.6 1 2 0 -0.0018 14 0 0 0 - - - - - 6.0703 1 221125_WJC_METTL3_EV_vs_WT_F09.06332.06332.2 1.16E-06 22/26 K.KGPGEVAGTVTGQK.R "sp|Q86U44|MTA70_HUMAN,tr|F5H6D8|F5H6D8_HUMAN,tr|H0YFV6|H0YFV6_HUMAN,tr|B4DTN4|B4DTN4_HUMAN" 4 1327.7096 0 127577 6332 2 1327.710466 664.8621 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 8.59 1641.9 - 4.02E+06 - - - 0.6681 - 3.777 0.58 - 1280.3 1 2 0 0.0009 14 0 0 0 8.52E+08 2.85E+11 - - - 6.6595 1 221125_WJC_METTL3_EV_vs_WT_F09.06352.06352.2 3.64E-10 21/30 R.ETGTEHSPGVQPADVK.E "sp|Q9H7C9|AAMDC_HUMAN,tr|K4DI89|K4DI89_HUMAN,tr|E9PLK9|E9PLK9_HUMAN,tr|E9PNP3|E9PNP3_HUMAN,tr|E9PJP1|E9PJP1_HUMAN" 5 1650.7849 3.18 127579 6352 2 1650.783489 826.3997 Mth938 domain-containing protein OS=Homo sapiens OX=9606 GN=AAMDC PE=1 SV=1 4.65 1645.1 - 3.96E+06 - - - -0.8723 - 3.679 0.677 - 1441.2 1 2 0 -0.0014 16 0 0 0 1.28E+08 4.03E+07 - - - 7.2435 1 221125_WJC_METTL3_EV_vs_WT_F09.06359.06359.3 0.0002 27/68 K.GTGGASAEGGPTGLAHGR[166.11].L sp|Q96F45|ZN503_HUMAN 1 1561.7473 1.58 127582 6359 3 1561.746407 521.5897 Zinc finger protein 503 OS=Homo sapiens OX=9606 GN=ZNF503 PE=1 SV=1 6.75 1646 - 3.55E+06 - - - -0.5411 - 3.799 0.499 - 614.1 1 2 0 -0.0008 18 0 0 0 3.26E+09 2.06E+09 - - - 7.4268 1 221125_WJC_METTL3_EV_vs_WT_F09.06365.06365.3 3.81E-08 29/68 K.GTGGASAEGGPTGLAHGR.L sp|Q96F45|ZN503_HUMAN 1 1551.739 1.58 127585 6365 3 1551.73685 518.2536 Zinc finger protein 503 OS=Homo sapiens OX=9606 GN=ZNF503 PE=1 SV=1 6.75 1646.7 - 3.38E+06 - - - -1.3739 - 4.657 0.59 - 1771.1 1 2 0 -0.0021 18 0 0 0 3.26E+09 2.06E+09 - - - 8.948 0.9052 221125_WJC_METTL3_EV_vs_WT_F09.06395.06395.2 0.0535 16-Jul E.VAGTVTGQK[136.11].R "sp|Q86U44|MTA70_HUMAN,tr|F5H6D8|F5H6D8_HUMAN,tr|H0YFV6|H0YFV6_HUMAN,tr|B4DTN4|B4DTN4_HUMAN" 4 867.4905 0.02 127589 6395 2 867.488722 434.7525 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 8.72 1651.4 - 3.60E+06 - - - -2.0853 - 1.622 0.295 - 110.5 1 1 0 -0.0018 9 0 0 0 1.51E+07 8.06E+08 - - - 2.6186 1 221125_WJC_METTL3_EV_vs_WT_F09.06407.06407.2 2.02E-12 22/32 R.PSDSVSSTPAATSTPSK.Q "sp|Q9ULV3|CIZ1_HUMAN,tr|Q5SYW2|Q5SYW2_HUMAN,tr|F5H2X7|F5H2X7_HUMAN,tr|H0Y5D5|H0Y5D5_HUMAN,tr|A0A494C0L7|A0A494C0L7_HUMAN,tr|Q9BTG3|Q9BTG3_HUMAN" 6 1618.7686 3.37 127592 6407 2 1618.767387 810.3916 Cip1-interacting zinc finger protein OS=Homo sapiens OX=9606 GN=CIZ1 PE=1 SV=2 6.26 1653.1 - 2.45E+06 - - - -0.7555 - 4.352 0.581 - 1760.6 1 1 0 -0.0012 17 0 0 0 4.74E+08 1.40E+08 - - - 6.9475 1 221125_WJC_METTL3_EV_vs_WT_F09.06417.06417.2 1.78E-07 19/32 R.PSDSVSSTPAATSTPSK[136.11].Q "sp|Q9ULV3|CIZ1_HUMAN,tr|Q5SYW2|Q5SYW2_HUMAN,tr|F5H2X7|F5H2X7_HUMAN,tr|H0Y5D5|H0Y5D5_HUMAN,tr|A0A494C0L7|A0A494C0L7_HUMAN,tr|Q9BTG3|Q9BTG3_HUMAN" 6 1626.7828 3.37 127594 6417 2 1626.779905 814.3987 Cip1-interacting zinc finger protein OS=Homo sapiens OX=9606 GN=CIZ1 PE=1 SV=2 6.26 1654.7 - 1.51E+06 - - - -1.7857 - 3.822 0.604 - 1195.4 1 1 0 -0.0029 17 0 0 0 4.74E+08 1.40E+08 - - - 6.7976 1 221125_WJC_METTL3_EV_vs_WT_F09.06426.06426.2 2.37E-06 15/24 K.GPGEVAGTVTGQK[136.11].R "sp|Q86U44|MTA70_HUMAN,tr|F5H6D8|F5H6D8_HUMAN,tr|H0YFV6|H0YFV6_HUMAN,tr|B4DTN4|B4DTN4_HUMAN" 4 1207.6288 0.001 127596 6426 2 1207.623799 604.8217 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 6 1656.1 - 785459 - - - -4.1544 - 2.849 0.572 - 1088.1 1 2 0 -0.005 13 0 0 0 0.00E+00 2.00E+08 - - - 5.9513 0.9998 221125_WJC_METTL3_EV_vs_WT_F09.06427.06427.2 5.18E-07 13/28 R.NTDQASMPDNTAAQK[136.11].V "sp|P35749|MYH11_HUMAN,sp|P35579|MYH9_HUMAN,tr|A0A494C024|A0A494C024_HUMAN" 3 1598.7086 1.12 127597 6427 2 1598.705348 800.3616 Myosin-11 OS=Homo sapiens OX=9606 GN=MYH11 PE=1 SV=3 4.21 1656.2 - 1.80E+06 - - - -2.0335 - 2.888 0.486 - 395.3 1 2 0 -0.0033 15 0 0 0 1.10E+08 9.81E+07 - - - 5.237 1 221125_WJC_METTL3_EV_vs_WT_F09.06433.06433.2 1.98E-07 17/28 R.NTDQASMPDNTAAQK.V "sp|P35749|MYH11_HUMAN,sp|P35579|MYH9_HUMAN,tr|A0A494C024|A0A494C024_HUMAN" 3 1590.6944 1.12 127599 6433 2 1590.696515 796.3545 Myosin-11 OS=Homo sapiens OX=9606 GN=MYH11 PE=1 SV=3 4.21 1657 - 1.63E+06 - - - 1.3302 - 3.32 0.666 - 847.2 1 2 0 0.0021 15 0 0 0 1.10E+08 9.81E+07 - - - 6.9096 1 221125_WJC_METTL3_EV_vs_WT_F09.06434.06434.2 8.98E-09 20/34 K.GTGGASAEGGPTGLAHGR[166.11].L sp|Q96F45|ZN503_HUMAN 1 1561.7473 1.79 127600 6434 2 1561.743785 781.8809 Zinc finger protein 503 OS=Homo sapiens OX=9606 GN=ZNF503 PE=1 SV=1 6.75 1657.1 - 1.20E+06 - - - -2.2199 - 3.755 0.581 - 1159.1 1 2 0 -0.0035 18 0 0 0 1.95E+08 1.09E+08 - - - 6.5841 1 221125_WJC_METTL3_EV_vs_WT_F09.06442.06442.2 1.03E-10 19/34 K.GTGGASAEGGPTGLAHGR.L sp|Q96F45|ZN503_HUMAN 1 1551.739 1.79 127601 6442 2 1551.731266 776.8768 Zinc finger protein 503 OS=Homo sapiens OX=9606 GN=ZNF503 PE=1 SV=1 6.75 1658.4 - 1.25E+06 - - - -4.9725 - 3.597 0.533 - 872.4 1 2 0 -0.0077 18 0 0 0 1.95E+08 1.09E+08 - - - 6.1225 0.9938 221125_WJC_METTL3_EV_vs_WT_F09.06448.06448.3 0.0578 Oct-40 K.VSNRFSGVPDR.F "sp|A0A075B6R9|KVD24_HUMAN,sp|A0A075B6S2|KVD29_HUMAN,sp|A0A0A0MRZ7|KVD26_HUMAN" 3 1232.6262 399.09 127604 6448 3 1232.624158 411.8827 Probable non-functional immunoglobulin kappa variable 2D-24 OS=Homo sapiens OX=9606 GN=IGKV2D-24 PE=1 SV=1 9.57 1659.1 - 1.31E+06 - - - -1.6436 - 1.918 0.265 - 176.7 1 2 1 -0.002 11 0 0 0 7.86E+07 1.97E+05 - - - 3.3441 1 221125_WJC_METTL3_EV_vs_WT_F09.06462.06462.2 4.99E-08 16/30 F.AGTNTGPNNSNTTFQK[136.11].R "sp|Q9NYF8|BCLF1_HUMAN,tr|H0YF14|H0YF14_HUMAN" 2 1658.774 2.24 127608 6462 2 1658.771124 830.3943 Bcl-2-associated transcription factor 1 OS=Homo sapiens OX=9606 GN=BCLAF1 PE=1 SV=2 8.8 1661.1 - 1.45E+06 - - - -1.7199 - 3.367 0.675 - 1027.6 1 1 0 -0.0029 16 0 0 0 9.95E+08 4.44E+08 - - - 7.0104 0.9999 221125_WJC_METTL3_EV_vs_WT_F09.06465.06465.3 0.00145 13/48 R.EDSVKPGAHLTVK.K "sp|P51991|ROA3_HUMAN,tr|A0A7I2V5D8|A0A7I2V5D8_HUMAN,tr|A0A7I2V2R3|A0A7I2V2R3_HUMAN,tr|A0A7I2V4J6|A0A7I2V4J6_HUMAN,tr|A0A7I2V4G0|A0A7I2V4G0_HUMAN,tr|A0A7I2V402|A0A7I2V402_HUMAN" 6 1379.7409 1.29 127609 6465 3 1379.737042 460.9209 Heterogeneous nuclear ribonucleoprotein A3 OS=Homo sapiens OX=9606 GN=HNRNPA3 PE=1 SV=2 6.85 1661.5 - 4.48E+06 - - - -2.781 - 2.446 0.465 - 141.8 1 2 0 -0.0038 13 0 0 0 1.32E+09 1.03E+09 - - - 6.1484 0.9998 221125_WJC_METTL3_EV_vs_WT_F09.06482.06482.2 1.91E-05 24-Dec R.EDSVKPGAHLTVK.K "sp|P51991|ROA3_HUMAN,tr|A0A7I2V5D8|A0A7I2V5D8_HUMAN,tr|A0A7I2V2R3|A0A7I2V2R3_HUMAN,tr|A0A7I2V4J6|A0A7I2V4J6_HUMAN,tr|A0A7I2V4G0|A0A7I2V4G0_HUMAN,tr|A0A7I2V402|A0A7I2V402_HUMAN" 6 1379.7409 1.36 127615 6482 2 1379.740479 690.8777 Heterogeneous nuclear ribonucleoprotein A3 OS=Homo sapiens OX=9606 GN=HNRNPA3 PE=1 SV=2 6.85 1663.9 - 625291 - - - -0.2899 - 1.975 0.444 - 266.2 1 2 0 -0.0004 13 0 0 0 5.43E+07 3.98E+07 - - - 4.067 0.9469 221125_WJC_METTL3_EV_vs_WT_F09.06484.06484.2 0.161 14-Aug V.AGTVTGQK[136.11].R "sp|Q86U44|MTA70_HUMAN,tr|F5H6D8|F5H6D8_HUMAN,tr|H0YFV6|H0YFV6_HUMAN,tr|B4DTN4|B4DTN4_HUMAN" 4 768.4221 0.17 127616 6484 2 768.421176 385.2183 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 8.8 1664.1 - 5.63E+06 - - - -1.2259 - 1.998 0.212 - 329.3 1 1 0 -0.0009 8 0 0 0 4.60E+08 2.74E+09 - - - 2.694 0.9797 221125_WJC_METTL3_EV_vs_WT_F09.06492.06492.3 0.205 Dec-44 E.DSVKPGAHLTVK.K "sp|P51991|ROA3_HUMAN,tr|A0A7I2V5D8|A0A7I2V5D8_HUMAN,tr|A0A7I2V2R3|A0A7I2V2R3_HUMAN,tr|A0A7I2V4J6|A0A7I2V4J6_HUMAN,tr|A0A7I2V4G0|A0A7I2V4G0_HUMAN,tr|A0A7I2V402|A0A7I2V402_HUMAN" 6 1250.6983 1.23 127621 6492 3 1250.694745 417.9067 Heterogeneous nuclear ribonucleoprotein A3 OS=Homo sapiens OX=9606 GN=HNRNPA3 PE=1 SV=2 8.6 1665.1 - 1.29E+06 - - - -2.8312 - 2.359 0.43 - 142.9 1 1 0 -0.0035 12 0 0 0 5.12E+07 4.16E+07 - - - 5.712 0.9995 221125_WJC_METTL3_EV_vs_WT_F09.06497.06497.3 0.00263 Aug-52 K.KGPGEVAGTVTGQK[136.11].R "sp|Q86U44|MTA70_HUMAN,tr|F5H6D8|F5H6D8_HUMAN,tr|H0YFV6|H0YFV6_HUMAN,tr|B4DTN4|B4DTN4_HUMAN" 4 1335.7238 - 127623 6497 3 1335.723808 446.2485 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 8.59 1665.8 - 3.57E+07 - - - 0.0217 - 2.14 0.317 - 89 4 2 0 0 14 0 0 0 - - - - - 3.8175 0.9999 221125_WJC_METTL3_EV_vs_WT_F09.06509.06509.3 2.37E-08 18/44 R.QTEEQVNDLKER.L sp|P12270|TPR_HUMAN 1 1487.7216 3.03 127630 6509 3 1487.718628 496.9145 Nucleoprotein TPR OS=Homo sapiens OX=9606 GN=TPR PE=1 SV=3 4.41 1667.3 - 1.94E+06 - - - -1.9977 - 3.33 0.492 - 924.1 1 2 1 -0.003 12 0 0 0 4.72E+07 1.56E+07 - - - 7.359 0.9984 221125_WJC_METTL3_EV_vs_WT_F09.06510.06510.3 0.0111 Oct-32 K.EHIKNPDWR.Y "sp|Q14974|IMB1_HUMAN,tr|J3KTM9|J3KTM9_HUMAN" 2 1193.5942 1.19 127631 6510 3 1193.59266 398.872 Importin subunit beta-1 OS=Homo sapiens OX=9606 GN=KPNB1 PE=1 SV=2 6.85 1667.4 - 571275 - - - -1.2525 - 1.909 0.335 - 211.3 1 2 1 -0.0015 9 0 0 0 2.41E+07 2.02E+07 - - - 4.2232 0.9999 221125_WJC_METTL3_EV_vs_WT_F09.06513.06513.3 2.72E-09 18/48 R.K[136.11]AVVVC[160.03]PK[136.11]DEDYK[136.11].Q "sp|Q00839|HNRPU_HUMAN,tr|A0A1W2PQL0|A0A1W2PQL0_HUMAN,tr|A0A1W2PPL4|A0A1W2PPL4_HUMAN,tr|A0A1W2PQ74|A0A1W2PQ74_HUMAN,tr|Q5RI18|Q5RI18_HUMAN,tr|A0A1W2PP35|A0A1W2PP35_HUMAN,tr|A0A1W2PPS1|A0A1W2PPS1_HUMAN,tr|A0A1W2PRZ7|A0A1W2PRZ7_HUMAN,tr|A0A1W2PPH7|A0A1W2PPH7_HUMAN,tr|A0A1W2PQD4|A0A1W2PQD4_HUMAN,tr|A0A1W2PP34|A0A1W2PP34_HUMAN,tr|A0A1X7SBS1|A0A1X7SBS1_HUMAN" 12 1573.8236 1.05 127632 6513 3 1573.821584 525.6152 Heterogeneous nuclear ribonucleoprotein U OS=Homo sapiens OX=9606 GN=HNRNPU PE=1 SV=6 6.11 1667.8 - 974985 - - - -1.3 - 2.863 0.542 - 376.1 1 2 1 -0.002 13 0 0 0 3.07E+07 2.92E+07 - - - 7.4341 0.9904 221125_WJC_METTL3_EV_vs_WT_F09.06514.06514.3 2.55E-07 18/44 E.DSVK[136.11]PGAHLTVK[136.11].K "sp|P51991|ROA3_HUMAN,tr|A0A7I2V5D8|A0A7I2V5D8_HUMAN,tr|A0A7I2V2R3|A0A7I2V2R3_HUMAN,tr|A0A7I2V4J6|A0A7I2V4J6_HUMAN,tr|A0A7I2V4G0|A0A7I2V4G0_HUMAN,tr|A0A7I2V402|A0A7I2V402_HUMAN" 6 1266.7267 1.24 127633 6514 3 1266.723123 423.2495 Heterogeneous nuclear ribonucleoprotein A3 OS=Homo sapiens OX=9606 GN=HNRNPA3 PE=1 SV=2 8.6 1667.9 - 1.62E+06 - - - -2.8128 - 2.722 0.473 - 316.6 1 1 0 -0.0036 12 0 0 0 5.23E+07 4.22E+07 - - - 6.5881 1 221125_WJC_METTL3_EV_vs_WT_F09.06516.06516.3 1.14E-05 14/52 K.K[136.11]GPGEVAGTVTGQK[136.11].R "sp|Q86U44|MTA70_HUMAN,tr|F5H6D8|F5H6D8_HUMAN,tr|H0YFV6|H0YFV6_HUMAN,tr|B4DTN4|B4DTN4_HUMAN" 4 1343.738 0 127634 6516 3 1343.737947 448.9199 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 8.59 1668.2 - 4.98E+08 - - - -0.0238 - 2.759 0.569 - 335.8 1 2 0 0 14 0 0 0 3.92E+07 6.03E+11 - - - 7.5808 0.9965 221125_WJC_METTL3_EV_vs_WT_F09.06517.06517.3 1.98E-06 Dec-60 F.AGTNTGPNNSNTTFQK.R "sp|Q9NYF8|BCLF1_HUMAN,tr|H0YF14|H0YF14_HUMAN" 2 1650.7598 2.56 127635 6517 3 1650.757453 551.2605 Bcl-2-associated transcription factor 1 OS=Homo sapiens OX=9606 GN=BCLAF1 PE=1 SV=2 8.8 1668.2 - 9.18E+06 - - - -1.4078 - 2.533 0.511 - 278.5 1 1 0 -0.0023 16 0 0 0 2.67E+08 1.04E+08 - - - 6.6212 1 221125_WJC_METTL3_EV_vs_WT_F09.06519.06519.3 1.73E-17 20/60 K.VDC[160.03]TAHSDVC[160.03]SAQGVR[166.11].G sp|Q8NBS9|TXND5_HUMAN 1 1770.7653 0.59 127637 6519 3 1770.762498 591.2624 Thioredoxin domain-containing protein 5 OS=Homo sapiens OX=9606 GN=TXNDC5 PE=1 SV=2 5.21 1668.4 - 1.28E+06 - - - -1.575 - 3.961 0.708 - 679.3 1 2 0 -0.0028 16 0 0 0 2.78E+07 4.69E+07 - - - 9.9646 0.9998 221125_WJC_METTL3_EV_vs_WT_F09.06520.06520.4 3.92E-07 13/72 R.KAVVVC[160.03]PKDEDYK.Q "sp|Q00839|HNRPU_HUMAN,tr|A0A1W2PQL0|A0A1W2PQL0_HUMAN,tr|A0A1W2PPL4|A0A1W2PPL4_HUMAN,tr|A0A1W2PQ74|A0A1W2PQ74_HUMAN,tr|Q5RI18|Q5RI18_HUMAN,tr|A0A1W2PP35|A0A1W2PP35_HUMAN,tr|A0A1W2PPS1|A0A1W2PPS1_HUMAN,tr|A0A1W2PRZ7|A0A1W2PRZ7_HUMAN,tr|A0A1W2PPH7|A0A1W2PPH7_HUMAN,tr|A0A1W2PQD4|A0A1W2PQD4_HUMAN,tr|A0A1W2PP34|A0A1W2PP34_HUMAN,tr|A0A1X7SBS1|A0A1X7SBS1_HUMAN" 12 1549.781 0.96 127638 6520 4 1549.779252 388.4525 Heterogeneous nuclear ribonucleoprotein U OS=Homo sapiens OX=9606 GN=HNRNPU PE=1 SV=6 6.11 1668.5 - 430717 - - - -1.1473 - 2.223 0.496 - 174.3 1 2 1 -0.0018 13 0 0 0 1.52E+07 1.58E+07 - - - 3.8389 0.9948 221125_WJC_METTL3_EV_vs_WT_F09.06526.06526.3 0.00034 Oct-60 F.AGTNTGPNNSNTTFQK[136.11].R "sp|Q9NYF8|BCLF1_HUMAN,tr|H0YF14|H0YF14_HUMAN" 2 1658.774 2.56 127642 6526 3 1658.771511 553.9319 Bcl-2-associated transcription factor 1 OS=Homo sapiens OX=9606 GN=BCLAF1 PE=1 SV=2 8.8 1669.2 - 3.18E+06 - - - -1.4866 - 2.308 0.494 - 204.1 1 1 0 -0.0025 16 0 0 0 2.67E+08 1.04E+08 - - - 6.193 1 221125_WJC_METTL3_EV_vs_WT_F09.06528.06528.3 1.09E-13 21/60 K.VDC[160.03]TAHSDVC[160.03]SAQGVR.G sp|Q8NBS9|TXND5_HUMAN 1 1760.757 0.59 127643 6528 3 1760.752209 587.9263 Thioredoxin domain-containing protein 5 OS=Homo sapiens OX=9606 GN=TXNDC5 PE=1 SV=2 5.21 1669.4 - 1.57E+06 - - - -2.7306 - 3.997 0.6 - 790.4 1 2 0 -0.0048 16 0 0 0 2.78E+07 4.69E+07 - - - 8.7832 1 221125_WJC_METTL3_EV_vs_WT_F09.06530.06530.2 1.37E-07 17/26 K.K[136.11]GPGEVAGTVTGQK[136.11].R "sp|Q86U44|MTA70_HUMAN,tr|F5H6D8|F5H6D8_HUMAN,tr|H0YFV6|H0YFV6_HUMAN,tr|B4DTN4|B4DTN4_HUMAN" 4 1343.738 0 127644 6530 2 1343.73595 672.8763 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 8.59 1669.6 - 9.36E+07 - - - -1.51 - 3.483 0.539 - 639.9 1 2 0 -0.002 14 0 0 0 8.54E+08 2.86E+11 - - - 6.1529 0.9798 221125_WJC_METTL3_EV_vs_WT_F09.06531.06531.2 0.0637 14-Oct R.PGAHLTVK.K "sp|Q32P51|RA1L2_HUMAN,sp|P51991|ROA3_HUMAN,sp|P09651|ROA1_HUMAN,tr|A0A7I2YQX9|A0A7I2YQX9_HUMAN,tr|A0A7I2V5D8|A0A7I2V5D8_HUMAN,tr|F8W646|F8W646_HUMAN,tr|A0A7I2V2R3|A0A7I2V2R3_HUMAN,tr|F8VZ49|F8VZ49_HUMAN,tr|A0A7I2V3R8|A0A7I2V3R8_HUMAN,tr|F8VTQ5|F8VTQ5_HUMAN,tr|F8W6I7|F8W6I7_HUMAN,tr|A0A7I2V2L6|A0A7I2V2L6_HUMAN,tr|A0A7I2V4J6|A0A7I2V4J6_HUMAN,tr|A0A7I2V3W0|A0A7I2V3W0_HUMAN,tr|A0A7I2V4G0|A0A7I2V4G0_HUMAN,tr|A0A7I2V5U9|A0A7I2V5U9_HUMAN,tr|A0A7I2V402|A0A7I2V402_HUMAN" 17 821.4759 1.27 127645 6531 2 821.47428 411.7452 Heterogeneous nuclear ribonucleoprotein A1-like 2 OS=Homo sapiens OX=9606 GN=HNRNPA1L2 PE=2 SV=2 9.18 1669.7 - 1.60E+06 - - - -2.0183 - 2.283 0.392 - 309.2 1 1 0 -0.0017 8 0 0 0 4.65E+07 3.67E+07 - - - 4.4254 1 221125_WJC_METTL3_EV_vs_WT_F09.06532.06532.3 2.39E-05 13/44 R.AFHNEAQVNPER[166.11].K "sp|P17987|TCPA_HUMAN,tr|F5H282|F5H282_HUMAN,tr|E7EQR6|E7EQR6_HUMAN" 3 1420.6723 1.24 127646 6532 3 1420.670525 474.5647 T-complex protein 1 subunit alpha OS=Homo sapiens OX=9606 GN=TCP1 PE=1 SV=1 5.4 1669.9 - 610803 - - - -1.2466 - 2.35 0.518 - 233.8 1 2 0 -0.0018 12 0 0 0 3.85E+07 3.11E+07 - - - 6.683 0.9996 221125_WJC_METTL3_EV_vs_WT_F09.06541.06541.2 0.00911 22-Nov R.EVFTSSSSSSSR.Q sp|P08779|K1C16_HUMAN 1 1259.563 300.02 127653 6541 2 1259.56068 630.7888 "Keratin, type I cytoskeletal 16 OS=Homo sapiens OX=9606 GN=KRT16 PE=1 SV=4" 6.1 1671 - 384425 - - - -1.8213 - 2.043 0.402 - 427.1 1 2 0 -0.0023 12 0 0 0 1.20E+07 3.99E+04 - - - 3.8892 0.9999 221125_WJC_METTL3_EV_vs_WT_F09.06545.06545.2 6.34E-05 17/26 K.K[136.11]GPGEVAGTVTGQK.R "sp|Q86U44|MTA70_HUMAN,tr|F5H6D8|F5H6D8_HUMAN,tr|H0YFV6|H0YFV6_HUMAN,tr|B4DTN4|B4DTN4_HUMAN" 4 1335.7238 - 127655 6545 2 1335.722907 668.8692 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 8.59 1671.4 - 1.78E+06 - - - -0.6528 - 3.144 0.487 - 543.7 1 2 0 -0.0009 14 0 0 0 - - - - - 5.5123 0.9999 221125_WJC_METTL3_EV_vs_WT_F09.06549.06549.3 6.39E-06 Dec-48 R.EDSVK[136.11]PGAHLTVK[136.11].K "sp|P51991|ROA3_HUMAN,tr|A0A7I2V5D8|A0A7I2V5D8_HUMAN,tr|A0A7I2V2R3|A0A7I2V2R3_HUMAN,tr|A0A7I2V4J6|A0A7I2V4J6_HUMAN,tr|A0A7I2V4G0|A0A7I2V4G0_HUMAN,tr|A0A7I2V402|A0A7I2V402_HUMAN" 6 1395.7693 1.29 127658 6549 3 1395.767051 466.2637 Heterogeneous nuclear ribonucleoprotein A3 OS=Homo sapiens OX=9606 GN=HNRNPA3 PE=1 SV=2 6.85 1671.8 - 2.72E+07 - - - -1.5963 - 2.182 0.448 - 121 1 2 0 -0.0022 13 0 0 0 1.32E+09 1.03E+09 - - - 5.6496 0.9936 221125_WJC_METTL3_EV_vs_WT_F09.06550.06550.3 0.00684 14/44 R.HSLASSEYPVR[166.11]R[166.11].R sp|P51570|GALK1_HUMAN 1 1420.7326 1.06 127659 6550 3 1420.735975 474.5848 Galactokinase OS=Homo sapiens OX=9606 GN=GALK1 PE=1 SV=1 8.75 1671.9 - 814709 - - - 2.3748 - 2.174 0.176 - 168.5 1 2 0 0.0034 12 0 0 0 2.93E+07 2.77E+07 - - - 2.6538 0.9976 221125_WJC_METTL3_EV_vs_WT_F09.06560.06560.2 0.00424 28-May R.EGSQGELTPANSQSR[166.11].M "sp|Q13098|CSN1_HUMAN,tr|A0A096LP07|A0A096LP07_HUMAN,tr|A8K070|A8K070_HUMAN,tr|C9JFE4|C9JFE4_HUMAN,tr|J3QQX0|J3QQX0_HUMAN,tr|A0A096LPJ3|A0A096LPJ3_HUMAN" 6 1569.7258 0.77 127665 6560 2 1569.723856 785.8702 COP9 signalosome complex subunit 1 OS=Homo sapiens OX=9606 GN=GPS1 PE=1 SV=4 4.53 1673.2 - 183935 - - - -1.269 - 1.13 0.344 - 71.4 1 2 0 -0.002 15 0 0 0 2.96E+06 3.82E+06 - - - 1.8816 0.8675 221125_WJC_METTL3_EV_vs_WT_F09.06570.06570.3 0.239 Oct-44 R.WKEPPGEEPVRK.K sp|Q9BUA3|SPNDC_HUMAN 1 1450.7569 2.05 127673 6570 3 1450.761098 484.5929 Spindlin interactor and repressor of chromatin-binding protein OS=Homo sapiens OX=9606 GN=SPINDOC PE=1 SV=3 6.23 1674.3 - 959583 - - - 2.9185 - 1.422 0.211 - 87.8 1 2 1 0.0042 12 0 0 0 3.48E+07 1.69E+07 - - - 1.8671 0.9837 221125_WJC_METTL3_EV_vs_WT_F09.06577.06577.3 0.444 Jul-44 R.HSLASSEYPVRR.R sp|P51570|GALK1_HUMAN 1 1400.7161 1.05 127678 6577 3 1400.714335 467.9126 Galactokinase OS=Homo sapiens OX=9606 GN=GALK1 PE=1 SV=1 8.75 1675.1 - 4.68E+06 - - - -1.2322 - 1.495 0.185 - 35.4 2 2 0 -0.0017 12 0 0 0 2.93E+07 2.78E+07 - - - 1.5774 0.9986 221125_WJC_METTL3_EV_vs_WT_F09.06578.06578.3 0.000736 15/48 K.IQDK[136.11]EGIPPDQQR[166.11].L "sp|P62979|RS27A_HUMAN,sp|P0CG48|UBC_HUMAN,sp|P0CG48|UBC_HUMAN,sp|P0CG48|UBC_HUMAN,sp|P0CG48|UBC_HUMAN,sp|P0CG48|UBC_HUMAN,sp|P0CG48|UBC_HUMAN,sp|P0CG48|UBC_HUMAN,sp|P0CG48|UBC_HUMAN,sp|P0CG48|UBC_HUMAN,sp|P0CG47|UBB_HUMAN,sp|P0CG47|UBB_HUMAN,sp|P0CG47|UBB_HUMAN,sp|P62987|RL40_HUMAN,tr|F5H388|F5H388_HUMAN,tr|F5H388|F5H388_HUMAN,tr|F5GYU3|F5GYU3_HUMAN,tr|F5GYU3|F5GYU3_HUMAN,tr|B4DV12|B4DV12_HUMAN,tr|B4DV12|B4DV12_HUMAN,tr|J3QSA3|J3QSA3_HUMAN,tr|Q5PY61|Q5PY61_HUMAN,tr|Q5PY61|Q5PY61_HUMAN,tr|Q5PY61|Q5PY61_HUMAN,tr|F5H2Z3|F5H2Z3_HUMAN,tr|F5H2Z3|F5H2Z3_HUMAN,tr|M0R2S1|M0R2S1_HUMAN,tr|J3QS39|J3QS39_HUMAN,tr|J3QTR3|J3QTR3_HUMAN,tr|Q96C32|Q96C32_HUMAN,tr|Q96C32|Q96C32_HUMAN,tr|Q96C32|Q96C32_HUMAN,tr|Q96C32|Q96C32_HUMAN,tr|M0R1V7|M0R1V7_HUMAN,tr|F5H747|F5H747_HUMAN,tr|F5H747|F5H747_HUMAN,tr|F5GXK7|F5GXK7_HUMAN,tr|F5GXK7|F5GXK7_HUMAN,tr|M0R1M6|M0R1M6_HUMAN,tr|F5H6Q2|F5H6Q2_HUMAN,tr|F5H6Q2|F5H6Q2_HUMAN,tr|F5GZ39|F5GZ39_HUMAN,tr|J3QKN0|J3QKN0_HUMAN,tr|J3QKN0|J3QKN0_HUMAN,tr|F5H265|F5H265_HUMAN,tr|F5H265|F5H265_HUMAN,tr|A0A2R8Y422|A0A2R8Y422_HUMAN" 47 1540.7964 0.6 127679 6578 3 1540.796111 514.6061 Ubiquitin-40S ribosomal protein S27a OS=Homo sapiens OX=9606 GN=RPS27A PE=1 SV=2 4.56 1675.3 - 659074 - - - -0.2135 - 2.175 0.319 - 347.4 1 2 1 -0.0003 13 0 0 0 2.98E+07 5.01E+07 - - - 4.2032 0.9999 221125_WJC_METTL3_EV_vs_WT_F09.06581.06581.3 1.04E-07 17/44 K.LKQVEDEKNSFR.E sp|P35579|MYH9_HUMAN 1 1491.7682 1.02 127682 6581 3 1491.767055 498.2633 Myosin-9 OS=Homo sapiens OX=9606 GN=MYH9 PE=1 SV=4 6.18 1675.6 - 468493 - - - -0.7387 - 2.996 0.476 - 301.2 1 2 2 -0.0011 12 0 0 0 5.26E+06 5.17E+06 - - - 6.8881 1 221125_WJC_METTL3_EV_vs_WT_F09.06591.06591.2 8.12E-12 16/30 F.AGTNTGPNNSNTTFQK.R "sp|Q9NYF8|BCLF1_HUMAN,tr|H0YF14|H0YF14_HUMAN" 2 1650.7598 2.24 127691 6591 2 1650.759565 826.3872 Bcl-2-associated transcription factor 1 OS=Homo sapiens OX=9606 GN=BCLAF1 PE=1 SV=2 8.8 1676.9 - 894014 - - - -0.1284 - 3.291 0.691 - 1028.9 1 1 0 -0.0002 16 0 0 0 9.95E+08 4.44E+08 - - - 7.0733 0.9997 221125_WJC_METTL3_EV_vs_WT_F09.06594.06594.3 0.0143 Dec-52 K.AQEQQQQMAELHSK.L "sp|Q9P2E9|RRBP1_HUMAN,tr|A0A087WVV2|A0A087WVV2_HUMAN,tr|F8W7S5|F8W7S5_HUMAN" 3 1654.7733 2.64 127694 6594 3 1654.774056 552.5984 Ribosome-binding protein 1 OS=Homo sapiens OX=9606 GN=RRBP1 PE=1 SV=5 5.4 1677.2 - 360759 - - - 0.446 - 2.147 0.33 - 240.1 1 2 0 0.0007 14 0 0 0 1.90E+07 7.20E+06 - - - 4.2495 0.9998 221125_WJC_METTL3_EV_vs_WT_F09.06596.06596.2 0.0175 16-Jun R.SQESGYYDR[166.11].M "sp|P43243|MATR3_HUMAN,tr|A8MXP9|A8MXP9_HUMAN,tr|D6R991|D6R991_HUMAN,tr|A0A0R4J2E8|A0A0R4J2E8_HUMAN,tr|D6REM6|D6REM6_HUMAN" 5 1113.4602 1.31 127696 6596 2 1113.460096 557.7374 Matrin-3 OS=Homo sapiens OX=9606 GN=MATR3 PE=1 SV=2 4.37 1677.4 - 243113 - - - -0.1266 - 1.479 0.503 - 182.1 1 2 0 -0.0001 9 0 0 0 2.36E+06 1.80E+06 - - - 3.8884 1 221125_WJC_METTL3_EV_vs_WT_F09.06604.06604.3 1.35E-07 21/68 K.GTGGASAEGGPTGLAHGR.L sp|Q96F45|ZN503_HUMAN 1 1551.739 1.58 127703 6604 3 1551.738145 518.2536 Zinc finger protein 503 OS=Homo sapiens OX=9606 GN=ZNF503 PE=1 SV=1 6.75 1678.5 - 737788 - - - -0.5394 - 3.539 0.534 - 554.3 1 2 0 -0.0008 18 0 0 0 3.24E+09 2.05E+09 - - - 7.6404 0.9879 221125_WJC_METTL3_EV_vs_WT_F09.06606.06606.2 7.22E-06 15/22 G.PGEVAGTVTGQK[136.11].R "sp|Q86U44|MTA70_HUMAN,tr|F5H6D8|F5H6D8_HUMAN,tr|H0YFV6|H0YFV6_HUMAN,tr|B4DTN4|B4DTN4_HUMAN" 4 1150.6074 0.15 127704 6606 2 1150.609587 576.311 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 6.43 1678.7 - 2.02E+06 - - - 1.9425 - 2.778 0.501 - 951.5 1 1 0 0.0022 12 0 0 0 4.69E+06 3.07E+07 - - - 5.429 0.9886 221125_WJC_METTL3_EV_vs_WT_F09.06610.06610.3 0.32 Aug-40 K.KDDESNLVEEK.S "sp|Q07866|KLC1_HUMAN,tr|G3V5R9|G3V5R9_HUMAN,tr|G3V3H3|G3V3H3_HUMAN,tr|G3V2P7|G3V2P7_HUMAN,tr|F8W6L3|F8W6L3_HUMAN,tr|E7EVH7|E7EVH7_HUMAN,tr|G3V2E7|G3V2E7_HUMAN,tr|G5E9S8|G5E9S8_HUMAN" 8 1304.6096 1.46 127708 6610 3 1304.608526 435.8771 Kinesin light chain 1 OS=Homo sapiens OX=9606 GN=KLC1 PE=1 SV=2 4.18 1679.1 - 295436 - - - -0.8156 - 1.473 0.187 - 91.9 1 2 0 -0.0011 11 0 0 0 3.36E+06 2.30E+06 - - - 1.7248 0.9998 221125_WJC_METTL3_EV_vs_WT_F09.06626.06626.4 0.000194 17/72 K.VMEEEGLKDEEKR.L sp|Q15208|STK38_HUMAN 1 1590.7559 3.99 127722 6626 4 1590.757998 398.6963 Serine\threonine-protein kinase 38 OS=Homo sapiens OX=9606 GN=STK38 PE=1 SV=1 4.42 1681.2 - 699185 - - - 1.2956 - 3.202 0.455 - 376.6 1 2 1 0.0021 13 0 0 0 1.25E+08 3.12E+07 - - - 3.6172 1 221125_WJC_METTL3_EV_vs_WT_F09.06628.06628.3 3.01E-07 Dec-56 K.NSLQEQQEEEEEAR[166.11]K[136.11].N sp|P35580|MYH10_HUMAN 1 1863.8565 1.13 127724 6628 3 1863.857619 622.2928 Myosin-10 OS=Homo sapiens OX=9606 GN=MYH10 PE=1 SV=3 4.21 1681.5 - 402918 - - - 0.5821 - 2.624 0.525 - 213.7 1 2 0 0.0011 15 0 0 0 9.65E+06 8.50E+06 - - - 6.9102 1 221125_WJC_METTL3_EV_vs_WT_F09.06629.06629.3 1.94E-05 14/56 K.NSLQEQQEEEEEARK.N sp|P35580|MYH10_HUMAN 1 1845.8341 1.13 127725 6629 3 1845.836822 616.2853 Myosin-10 OS=Homo sapiens OX=9606 GN=MYH10 PE=1 SV=3 4.21 1681.6 - 394555 - - - 1.4942 - 3.15 0.512 - 399 1 2 0 0.0028 15 0 0 0 9.65E+06 8.50E+06 - - - 7.2415 0.9997 221125_WJC_METTL3_EV_vs_WT_F09.06630.06630.4 1.12E-06 13/72 K.VMEEEGLK[136.11]DEEK[136.11]R[166.11].L sp|Q15208|STK38_HUMAN 1 1616.7926 3.99 127726 6630 4 1616.795659 405.2054 Serine\threonine-protein kinase 38 OS=Homo sapiens OX=9606 GN=STK38 PE=1 SV=1 4.42 1681.7 - 320956 - - - 1.8877 - 2.401 0.476 - 203.6 1 2 1 0.0031 13 0 0 0 1.24E+08 3.12E+07 - - - 3.693 0.9993 221125_WJC_METTL3_EV_vs_WT_F09.06640.06640.3 0.0165 17/48 K.VMEEEGLKDEEKR.L sp|Q15208|STK38_HUMAN 1 1590.7559 4.03 127735 6640 3 1590.761978 531.2593 Serine\threonine-protein kinase 38 OS=Homo sapiens OX=9606 GN=STK38 PE=1 SV=1 4.42 1683 - 2.77E+06 - - - 3.7976 - 3.397 0.455 - 506.5 1 2 1 0.006 13 0 0 0 1.06E+08 2.64E+07 - - - 6.9267 0.9999 221125_WJC_METTL3_EV_vs_WT_F09.06642.06642.3 0.000148 15/48 K.VMEEEGLK[136.11]DEEK[136.11]R[166.11].L sp|Q15208|STK38_HUMAN 1 1616.7926 4.02 127736 6642 3 1616.794394 539.9381 Serine\threonine-protein kinase 38 OS=Homo sapiens OX=9606 GN=STK38 PE=1 SV=1 4.42 1683.2 - 1.03E+06 - - - 1.1053 - 2.746 0.534 - 339.7 1 2 1 0.0018 13 0 0 0 1.06E+08 2.64E+07 - - - 7.2319 0.9508 221125_WJC_METTL3_EV_vs_WT_F09.06647.06647.2 0.889 12-Jul K.ITITNDK[136.11].G "sp|P54652|HSP72_HUMAN,sp|P0DMV8|HS71A_HUMAN,sp|P34931|HS71L_HUMAN,sp|P11142|HSP7C_HUMAN,sp|P0DMV9|HS71B_HUMAN,sp|P17066|HSP76_HUMAN,tr|E9PNE6|E9PNE6_HUMAN,tr|A8K7Q2|A8K7Q2_HUMAN,tr|E9PKE3|E9PKE3_HUMAN,tr|E9PM13|E9PM13_HUMAN,tr|E9PS65|E9PS65_HUMAN,tr|Q53FA3|Q53FA3_HUMAN,tr|V9GZ37|V9GZ37_HUMAN,tr|A0A0G2JIW1|A0A0G2JIW1_HUMAN" 14 811.4531 0.37 127741 6647 2 812.456327 406.7338 Heat shock-related 70 kDa protein 2 OS=Homo sapiens OX=9606 GN=HSPA2 PE=1 SV=1 5.84 1683.8 - 619464 - - - 1236.3549 - 1.571 0.272 - 153.6 1 2 0 1.0032 7 0 0 0 3.62E+06 9.82E+06 - - - 2.1662 1 221125_WJC_METTL3_EV_vs_WT_F09.06652.06652.2 1.42E-09 16/26 K.IHSDC[160.03]AANQQVTYR.L sp|Q02413|DSG1_HUMAN 1 1661.758 999 127746 6652 2 1661.759664 831.8863 Desmoglein-1 OS=Homo sapiens OX=9606 GN=DSG1 PE=1 SV=2 6.73 1684.5 - 130115 - - - 0.9995 - 2.858 0.705 - 686.3 1 2 0 0.0017 14 0 0 0 7.30E+06 0.00E+00 - - - 6.8828 1 221125_WJC_METTL3_EV_vs_WT_F09.06658.06658.3 8.64E-08 15/48 K.KEAPPMEKPEVVK.T "sp|P62841|RS15_HUMAN,tr|K7EJ78|K7EJ78_HUMAN,tr|K7EM56|K7EM56_HUMAN,tr|A0A0B4J2B4|A0A0B4J2B4_HUMAN,tr|S4R456|S4R456_HUMAN,tr|K7ELC2|K7ELC2_HUMAN,tr|K7EQJ5|K7EQJ5_HUMAN,tr|S4R417|S4R417_HUMAN" 8 1480.796 1.4 127750 6658 3 1480.79741 494.6059 40S ribosomal protein S15 OS=Homo sapiens OX=9606 GN=RPS15 PE=1 SV=2 6.23 1685.2 - 445332 - - - 0.9853 - 2.997 0.507 - 258.5 1 2 0 0.0015 13 0 0 0 7.52E+07 5.37E+07 - - - 7.1681 0.8143 221125_WJC_METTL3_EV_vs_WT_F09.06662.06662.2 0.0688 20-Nov M.EEEGLKDEEKR.L sp|Q15208|STK38_HUMAN 1 1360.647 14.13 127754 6662 2 1360.649059 681.3308 Serine\threonine-protein kinase 38 OS=Homo sapiens OX=9606 GN=STK38 PE=1 SV=1 4.42 1685.8 - 185754 - - - 1.4853 - 2.31 0.377 - 376.1 1 1 1 0.002 11 0 0 0 2.34E+06 1.66E+05 - - - 4.0898 1 221125_WJC_METTL3_EV_vs_WT_F09.06664.06664.3 1.70E-08 13/56 R.RPSQDDVEAAPEETR.A sp|O94761|RECQ4_HUMAN 1 1698.7809 1.28 127756 6664 3 1698.779969 567.2676 ATP-dependent DNA helicase Q4 OS=Homo sapiens OX=9606 GN=RECQL4 PE=1 SV=2 4.18 1686 - 111113 - - - -0.5516 - 3.259 0.584 - 237.7 1 2 0 -0.0009 15 0 0 0 3.09E+06 2.42E+06 - - - 8.1335 0.9999 221125_WJC_METTL3_EV_vs_WT_F09.06668.06668.3 0.00183 Dec-40 R.DSSPHFQAEQR[166.11].V sp|Q9UH99|SUN2_HUMAN 1 1310.5879 5 127758 6668 3 1310.584762 437.8699 SUN domain-containing protein 2 OS=Homo sapiens OX=9606 GN=SUN2 PE=1 SV=3 5.32 1686.6 - 435055 - - - -2.3921 - 2.441 0.496 - 258.2 1 2 0 -0.0031 11 0 0 0 2.45E+07 4.90E+06 - - - 6.6042 0.9995 221125_WJC_METTL3_EV_vs_WT_F09.06669.06669.3 0.00102 Nov-36 R.DR[166.11]DAHAVDFR[166.11].G "sp|P78332|RBM6_HUMAN,tr|F8WCA5|F8WCA5_HUMAN,tr|E9PGM9|E9PGM9_HUMAN" 3 1220.5801 1.08 127759 6669 3 1220.579104 407.8673 RNA-binding protein 6 OS=Homo sapiens OX=9606 GN=RBM6 PE=1 SV=5 5.3 1686.7 - 387499 - - - -0.8348 - 1.866 0.422 - 181 1 2 1 -0.001 10 0 0 0 3.86E+06 3.56E+06 - - - 5.0664 0.9991 221125_WJC_METTL3_EV_vs_WT_F09.06671.06671.3 2.08E-05 Oct-36 R.DRDAHAVDFR.G "sp|P78332|RBM6_HUMAN,tr|F8WCA5|F8WCA5_HUMAN,tr|E9PGM9|E9PGM9_HUMAN" 3 1200.5636 0.98 127761 6671 3 1200.560672 401.1951 RNA-binding protein 6 OS=Homo sapiens OX=9606 GN=RBM6 PE=1 SV=5 5.3 1687 - 306463 - - - -2.4247 - 1.836 0.461 - 191 1 2 1 -0.0029 10 0 0 0 4.19E+06 4.26E+06 - - - 5.4533 1 221125_WJC_METTL3_EV_vs_WT_F09.06672.06672.3 1.60E-05 Dec-60 K.SPPPPTHSTQLGAPSR.K sp|Q14814|MEF2D_HUMAN 1 1628.8271 2.17 127762 6672 3 1628.827594 543.9496 Myocyte-specific enhancer factor 2D OS=Homo sapiens OX=9606 GN=MEF2D PE=1 SV=1 9.49 1687.1 - 286669 - - - 0.3229 - 2.412 0.488 - 151.5 1 2 0 0.0005 16 0 0 0 1.02E+07 4.68E+06 - - - 6.2397 1 221125_WJC_METTL3_EV_vs_WT_F09.06673.06673.3 8.53E-09 18/64 R.LNSEQSQALQHQQETGR.S "sp|Q92817|EVPL_HUMAN,tr|K7EKI0|K7EKI0_HUMAN" 2 1952.93 56.83 127763 6673 3 1952.935071 651.984 Envoplakin OS=Homo sapiens OX=9606 GN=EVPL PE=1 SV=3 5.4 1687.2 - 239238 - - - 2.5812 - 3.419 0.573 - 361.9 1 2 0 0.005 17 0 0 0 3.07E+06 5.39E+04 - - - 8.0327 0.9978 221125_WJC_METTL3_EV_vs_WT_F09.06674.06674.2 8.16E-05 24-Sep K.VMEEEGLKDEEKR.L sp|Q15208|STK38_HUMAN 1 1590.7559 4.75 127764 6674 2 1590.753267 796.3852 Serine\threonine-protein kinase 38 OS=Homo sapiens OX=9606 GN=STK38 PE=1 SV=1 4.42 1687.4 - 170953 - - - -1.6784 - 2.237 0.526 - 175.4 1 2 1 -0.0027 13 0 0 0 1.71E+06 3.61E+05 - - - 4.9916 1 221125_WJC_METTL3_EV_vs_WT_F09.06678.06678.3 2.12E-12 21/48 K.K[136.11]EAPPMEK[136.11]PEVVK[136.11].T "sp|P62841|RS15_HUMAN,tr|K7EJ78|K7EJ78_HUMAN,tr|K7EM56|K7EM56_HUMAN,tr|A0A0B4J2B4|A0A0B4J2B4_HUMAN,tr|S4R456|S4R456_HUMAN,tr|K7ELC2|K7ELC2_HUMAN,tr|K7EQJ5|K7EQJ5_HUMAN,tr|S4R417|S4R417_HUMAN" 8 1504.8386 1.4 127766 6678 3 1504.83826 502.6201 40S ribosomal protein S15 OS=Homo sapiens OX=9606 GN=RPS15 PE=1 SV=2 6.23 1687.9 - 1.10E+06 - - - -0.1934 - 3.671 0.521 - 588.2 1 2 0 -0.0003 13 0 0 0 7.60E+07 5.42E+07 - - - 7.8745 1 221125_WJC_METTL3_EV_vs_WT_F09.06679.06679.3 2.56E-07 13/52 R.HDSVFVAAHTSAGK[136.11].T sp|Q15477|SKIV2_HUMAN 1 1433.7143 1.15 127767 6679 3 1433.71601 478.912 Helicase SKI2W OS=Homo sapiens OX=9606 GN=SKIV2L PE=1 SV=3 6.92 1688 - 274351 - - - 1.2087 - 2.964 0.493 - 135.4 1 2 0 0.0017 14 0 0 0 7.02E+06 6.10E+06 - - - 6.9235 0.9998 221125_WJC_METTL3_EV_vs_WT_F09.06680.06680.3 0.000317 Dec-52 R.LQSIGTENTEENRR.F "sp|P04075|ALDOA_HUMAN,tr|H3BR04|H3BR04_HUMAN,tr|H3BMQ8|H3BMQ8_HUMAN,tr|H3BQN4|H3BQN4_HUMAN,tr|H3BUH7|H3BUH7_HUMAN,tr|J3KPS3|J3KPS3_HUMAN,tr|H3BPS8|H3BPS8_HUMAN" 7 1645.802 1.85 127768 6680 3 1645.800004 549.6079 Fructose-bisphosphate aldolase A OS=Homo sapiens OX=9606 GN=ALDOA PE=1 SV=2 4.79 1688.1 - 1.04E+06 - - - -1.1982 - 2.258 0.365 - 167.8 1 2 0 -0.002 14 0 0 0 2.43E+07 1.32E+07 - - - 4.7733 0.917 221125_WJC_METTL3_EV_vs_WT_F09.06681.06681.3 0.000103 Oct-40 Q.K[136.11]LLEQYK[136.11]EESK[136.11].K "sp|Q00839|HNRPU_HUMAN,tr|A0A1W2PQL0|A0A1W2PQL0_HUMAN,tr|A0A1W2PPL4|A0A1W2PPL4_HUMAN,tr|Q5RI18|Q5RI18_HUMAN,tr|A0A1W2PP35|A0A1W2PP35_HUMAN,tr|A0A1W2PPS1|A0A1W2PPS1_HUMAN,tr|A0A1W2PPH7|A0A1W2PPH7_HUMAN,tr|A0A1W2PQD4|A0A1W2PQD4_HUMAN,tr|A0A1W2PP34|A0A1W2PP34_HUMAN,tr|A0A1X7SBS1|A0A1X7SBS1_HUMAN" 10 1417.7879 1.19 127769 6681 3 1417.787178 473.6032 Heterogeneous nuclear ribonucleoprotein U OS=Homo sapiens OX=9606 GN=HNRNPU PE=1 SV=6 6.23 1688.2 - 722855 - - - -0.5064 - 2.241 0.34 - 132.4 1 1 1 -0.0007 11 0 0 0 1.46E+07 1.23E+07 - - - 4.6228 0.9958 221125_WJC_METTL3_EV_vs_WT_F09.06686.06686.3 0.00659 Oct-40 K.LK[136.11]DDEVAQLK[136.11]K[136.11].S "sp|P07195|LDHB_HUMAN,tr|A0A5F9ZHM4|A0A5F9ZHM4_HUMAN" 2 1309.7668 0.6 127772 6686 3 1309.766088 437.5962 L-lactate dehydrogenase B chain OS=Homo sapiens OX=9606 GN=LDHB PE=1 SV=2 6.12 1688.9 - 374401 - - - -0.5176 - 1.701 0.298 - 80 1 2 1 -0.0007 11 0 0 0 8.71E+06 1.45E+07 - - - 3.3713 0.9116 221125_WJC_METTL3_EV_vs_WT_F09.06688.06688.3 0.0203 Jul-56 K.C[160.03]PHC[160.03]DYAGTQSGSLK.Y sp|Q9P2Y4|ZN219_HUMAN 1 1679.7032 0.86 127774 6688 3 1679.700873 560.9083 Zinc finger protein 219 OS=Homo sapiens OX=9606 GN=ZNF219 PE=1 SV=2 6.72 1689.2 - 234176 - - - -1.3794 - 1.372 0.113 - 42 1 2 0 -0.0023 15 0 0 0 2.05E+06 2.39E+06 - - - 0.6245 0.999 221125_WJC_METTL3_EV_vs_WT_F09.06691.06691.2 7.61E-05 26-May R.EC[160.03]NPPNSQPASYQR.R "sp|Q13427|PPIG_HUMAN,tr|A0A7I2V629|A0A7I2V629_HUMAN,tr|C9JM79|C9JM79_HUMAN,tr|E9PG73|E9PG73_HUMAN,tr|A0A7I2V4F2|A0A7I2V4F2_HUMAN,tr|A0A7I2V5Q5|A0A7I2V5Q5_HUMAN" 6 1646.7107 1.23 127777 6691 2 1646.715546 824.3626 Peptidyl-prolyl cis-trans isomerase G OS=Homo sapiens OX=9606 GN=PPIG PE=1 SV=2 6.09 1689.6 - 79883 - - - 2.9319 - 1.213 0.595 - 55.3 1 2 0 0.0048 14 0 0 0 3.49E+06 2.84E+06 - - - 3.9187 0.9997 221125_WJC_METTL3_EV_vs_WT_F09.06704.06704.3 0.000794 Jul-64 K.LINDC[160.03]HGSVSEASSEQK.L "sp|P50851|LRBA_HUMAN,tr|E9PEM5|E9PEM5_HUMAN,tr|A0A494BZW2|A0A494BZW2_HUMAN,tr|A0A494C1L5|A0A494C1L5_HUMAN,tr|A0A494C0R9|A0A494C0R9_HUMAN" 5 1859.832 0.48 127786 6704 3 1859.833033 620.9513 Lipopolysaccharide-responsive and beige-like anchor protein OS=Homo sapiens OX=9606 GN=LRBA PE=1 SV=4 4.65 1691.2 - 166317 - - - 0.5791 - 1.284 0.443 - 37.6 1 2 0 0.0011 17 0 0 0 2.15E+06 4.47E+06 - - - 4.1102 0.9949 221125_WJC_METTL3_EV_vs_WT_F09.06707.06707.3 0.00514 Jul-56 R.TLSTSDDVEDR[166.11]ENEK[136.11].G sp|Q96A65|EXOC4_HUMAN 1 1754.7925 0.87 127789 6707 3 1754.795715 585.9381 Exocyst complex component 4 OS=Homo sapiens OX=9606 GN=EXOC4 PE=1 SV=1 4.02 1691.6 - 145801 - - - 1.811 - 1.527 0.357 - 26.1 1 2 1 0.0032 15 0 0 0 2.91E+06 3.34E+06 - - - 3.6239 0.9994 221125_WJC_METTL3_EV_vs_WT_F09.06709.06709.2 0.000411 26-Mar R.EC[160.03]NPPNSQPASYQR[166.11].R "sp|Q13427|PPIG_HUMAN,tr|A0A7I2V629|A0A7I2V629_HUMAN,tr|C9JM79|C9JM79_HUMAN,tr|E9PG73|E9PG73_HUMAN,tr|A0A7I2V4F2|A0A7I2V4F2_HUMAN,tr|A0A7I2V5Q5|A0A7I2V5Q5_HUMAN" 6 1656.719 1.23 127791 6709 2 1656.717899 829.3668 Peptidyl-prolyl cis-trans isomerase G OS=Homo sapiens OX=9606 GN=PPIG PE=1 SV=2 6.09 1691.9 - 90300 - - - -0.6573 - 0.849 0.579 - 24 1 2 0 -0.0011 14 0 0 0 3.49E+06 2.84E+06 - - - 2.9064 0.9942 221125_WJC_METTL3_EV_vs_WT_F09.06710.06710.3 0.000498 Oct-56 R.TLSTSDDVEDRENEK.G sp|Q96A65|EXOC4_HUMAN 1 1736.7701 0.86 127792 6710 3 1736.778379 579.9306 Exocyst complex component 4 OS=Homo sapiens OX=9606 GN=EXOC4 PE=1 SV=1 4.02 1692 - 86322.8 - - - 4.7859 - 1.735 0.478 - 78.9 1 2 1 0.0083 15 0 0 0 2.91E+06 3.39E+06 - - - 5.3047 0.9996 221125_WJC_METTL3_EV_vs_WT_F09.06717.06717.3 0.000259 Nov-60 K.SPPPPTHSTQLGAPSR[166.11].K sp|Q14814|MEF2D_HUMAN 1 1638.8353 2.24 127797 6717 3 1638.842619 547.2857 Myocyte-specific enhancer factor 2D OS=Homo sapiens OX=9606 GN=MEF2D PE=1 SV=1 9.49 1693 - 204449 - - - 4.4428 - 2.396 0.493 - 125.1 1 2 0 0.0073 16 0 0 0 8.96E+06 4.01E+06 - - - 6.2765 0.995 221125_WJC_METTL3_EV_vs_WT_F09.06725.06725.3 0.0327 Nov-52 R.LQSIGTENTEENR[166.11]R[166.11].F "sp|P04075|ALDOA_HUMAN,tr|H3BR04|H3BR04_HUMAN,tr|H3BMQ8|H3BMQ8_HUMAN,tr|H3BQN4|H3BQN4_HUMAN,tr|H3BUH7|H3BUH7_HUMAN,tr|J3KPS3|J3KPS3_HUMAN,tr|H3BPS8|H3BPS8_HUMAN" 7 1665.8185 1.85 127803 6725 3 1665.82656 556.2801 Fructose-bisphosphate aldolase A OS=Homo sapiens OX=9606 GN=ALDOA PE=1 SV=2 4.79 1694.1 - 658422 - - - 4.8289 - 1.893 0.349 - 140.7 1 2 0 0.008 14 0 0 0 2.43E+07 1.32E+07 - - - 4.1247 1 221125_WJC_METTL3_EV_vs_WT_F09.06730.06730.2 6.68E-09 16/36 R.TSLAGDTSNSSSPASTGAK.T "sp|Q9UPN3|MACF1_HUMAN,tr|A0A804HL78|A0A804HL78_HUMAN,tr|H3BQK9|H3BQK9_HUMAN,tr|H0Y314|H0Y314_HUMAN,tr|A0A7P0MQR8|A0A7P0MQR8_HUMAN,tr|H0Y390|H0Y390_HUMAN,tr|H0Y4F5|H0Y4F5_HUMAN,tr|H3BPE1|H3BPE1_HUMAN,tr|H0Y6T5|H0Y6T5_HUMAN,tr|A0A590UJG2|A0A590UJG2_HUMAN" 10 1737.8017 1.35 127807 6730 2 1737.805423 869.9081 "Microtubule-actin cross-linking factor 1, isoforms 1\2\3\5 OS=Homo sapiens OX=9606 GN=MACF1 PE=1 SV=4" 5.5 1694.7 - 94622.4 - - - 2.1418 - 3.403 0.72 - 827.6 1 2 0 0.0037 19 0 0 0 3.80E+06 2.81E+06 - - - 7.3686 0.7813 221125_WJC_METTL3_EV_vs_WT_F09.06733.06733.2 1.58 28-Mar R.TAQGLPGTSNSNSSR[166.11].S "sp|Q9P275|UBP36_HUMAN,tr|A0A075B784|A0A075B784_HUMAN" 2 1485.7047 1.14 127810 6733 2 1485.708303 743.8596 Ubiquitin carboxyl-terminal hydrolase 36 OS=Homo sapiens OX=9606 GN=USP36 PE=1 SV=4 9.41 1695.1 - 53785.9 - - - 2.413 - 0.787 0.133 - 18.5 3 2 0 0.0036 15 0 0 0 1.39E+06 1.22E+06 - - - -0.7798 0.9973 221125_WJC_METTL3_EV_vs_WT_F09.06742.06742.3 0.0471 Sep-64 R.ISSATASGQKPTTLPQK.V "sp|Q6EMB2|TTLL5_HUMAN,tr|G3V2J9|G3V2J9_HUMAN,tr|G3V4R8|G3V4R8_HUMAN" 3 1713.9261 1.71 127817 6742 3 1713.931244 572.316 Tubulin polyglutamylase TTLL5 OS=Homo sapiens OX=9606 GN=TTLL5 PE=1 SV=3 10 1696.3 - 128057 - - - 2.9931 - 1.814 0.315 - 54 1 2 0 0.0051 17 0 0 0 2.04E+06 1.19E+06 - - - 3.555 0.9999 221125_WJC_METTL3_EV_vs_WT_F09.06756.06756.3 2.04E-05 13/52 K.ETQIITGSDESC[160.03]RK.D "sp|Q9HAW4|CLSPN_HUMAN,tr|E7ESG2|E7ESG2_HUMAN" 2 1622.757 1.19 127827 6756 3 1622.761926 541.9263 Claspin OS=Homo sapiens OX=9606 GN=CLSPN PE=1 SV=3 4.68 1698.1 - 251691 - - - 3.0356 - 2.341 0.502 - 244.4 1 2 0 0.0049 14 0 0 0 3.36E+06 2.83E+06 - - - 6.3959 0.9998 221125_WJC_METTL3_EV_vs_WT_F09.06757.06757.3 9.24E-06 Oct-60 R.KEASDPQPEEADGGLK.S sp|P52907|CAZA1_HUMAN 1 1669.7795 1.44 127828 6757 3 1669.784659 557.6004 F-actin-capping protein subunit alpha-1 OS=Homo sapiens OX=9606 GN=CAPZA1 PE=1 SV=3 4.18 1698.3 - 167957 - - - 3.0842 - 2.203 0.471 - 98.3 1 2 0 0.0052 16 0 0 0 6.41E+06 4.45E+06 - - - 5.8163 0.9989 221125_WJC_METTL3_EV_vs_WT_F09.06759.06759.3 0.000535 Aug-56 K.QPC[160.03]TPPPQPQQQQVK.Q sp|P35321|SPR1A_HUMAN 1 1759.8676 999 127830 6759 3 1759.871427 587.6298 Cornifin-A OS=Homo sapiens OX=9606 GN=SPRR1A PE=1 SV=2 8.22 1698.5 - 113107 - - - 2.2013 - 1.657 0.356 - 79.1 1 2 0 0.0039 15 0 0 0 1.70E+06 0.00E+00 - - - 3.8257 0.9999 221125_WJC_METTL3_EV_vs_WT_F09.06761.06761.3 4.78E-07 16/52 K.K[136.11]GPGEVAGTVTGQK[136.11].R "sp|Q86U44|MTA70_HUMAN,tr|F5H6D8|F5H6D8_HUMAN,tr|H0YFV6|H0YFV6_HUMAN,tr|B4DTN4|B4DTN4_HUMAN" 4 1343.738 0 127831 6761 3 1343.742993 448.9199 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 8.59 1698.8 - 6.65E+06 - - - 3.7314 - 3.17 0.569 - 494.2 1 2 0 0.005 14 0 0 0 2.79E+05 1.21E+08 - - - 7.9485 0.9716 221125_WJC_METTL3_EV_vs_WT_F09.06767.06767.2 0.00184 24-Jul R.KGQDSIEPVPGQK.G sp|Q9NR50|EI2BG_HUMAN 1 1381.7201 0.76 127836 6767 2 1381.726561 691.8673 Translation initiation factor eIF-2B subunit gamma OS=Homo sapiens OX=9606 GN=EIF2B3 PE=1 SV=1 6.07 1699.5 - 87042.7 - - - 4.6442 - 1.493 0.239 - 115.1 1 2 0 0.0064 13 0 0 0 1.30E+06 1.72E+06 - - - 1.8329 1 221125_WJC_METTL3_EV_vs_WT_F09.06770.06770.2 4.60E-06 21/26 K.K[136.11]GPGEVAGTVTGQK[136.11].R "sp|Q86U44|MTA70_HUMAN,tr|F5H6D8|F5H6D8_HUMAN,tr|H0YFV6|H0YFV6_HUMAN,tr|B4DTN4|B4DTN4_HUMAN" 4 1343.738 0.001 127838 6770 2 1343.7412 672.8763 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 8.59 1699.9 - 1.18E+06 - - - 2.397 - 3.682 0.56 - 1206.8 1 2 0 0.0032 14 0 0 0 0.00E+00 2.29E+07 - - - 6.4471 0.9999 221125_WJC_METTL3_EV_vs_WT_F09.06772.06772.3 1.77E-07 13/48 K.KAEGEPQEESPLK.S "sp|Q9NYF8|BCLF1_HUMAN,tr|E9PKI6|E9PKI6_HUMAN,tr|A0A1W2PQ43|A0A1W2PQ43_HUMAN,tr|E9PK91|E9PK91_HUMAN,tr|E9PJA7|E9PJA7_HUMAN,tr|E9PK09|E9PK09_HUMAN,tr|E9PQN2|E9PQN2_HUMAN" 7 1440.7096 2.33 127839 6772 3 1440.715529 481.2438 Bcl-2-associated transcription factor 1 OS=Homo sapiens OX=9606 GN=BCLAF1 PE=1 SV=2 4.49 1700.1 - 1.40E+06 - - - 4.0883 - 2.733 0.546 - 325.3 1 2 0 0.0059 13 0 0 0 1.67E+08 7.17E+07 - - - 7.3517 0.9875 221125_WJC_METTL3_EV_vs_WT_F09.06773.06773.3 0.000113 Oct-48 R.KGQDSIEPVPGQK.G sp|Q9NR50|EI2BG_HUMAN 1 1381.7201 0.92 127840 6773 3 1381.723891 461.5807 Translation initiation factor eIF-2B subunit gamma OS=Homo sapiens OX=9606 GN=EIF2B3 PE=1 SV=1 6.07 1700.2 - 941518 - - - 2.7118 - 1.947 0.182 - 114.1 1 2 0 0.0037 13 0 0 0 1.43E+07 1.55E+07 - - - 2.3746 1 221125_WJC_METTL3_EV_vs_WT_F09.06774.06774.3 2.67E-07 15/48 K.K[136.11]AEGEPQEESPLK[136.11].S "sp|Q9NYF8|BCLF1_HUMAN,tr|E9PKI6|E9PKI6_HUMAN,tr|A0A1W2PQ43|A0A1W2PQ43_HUMAN,tr|E9PK91|E9PK91_HUMAN,tr|E9PJA7|E9PJA7_HUMAN,tr|E9PK09|E9PK09_HUMAN,tr|E9PQN2|E9PQN2_HUMAN" 7 1456.738 0.84 127841 6774 3 1456.742193 486.5866 Bcl-2-associated transcription factor 1 OS=Homo sapiens OX=9606 GN=BCLAF1 PE=1 SV=2 4.49 1700.3 - 497278 - - - 2.8516 - 2.806 0.594 - 520.1 1 2 0 0.0042 13 0 0 0 1.72E+07 2.06E+07 - - - 7.9588 0.9582 221125_WJC_METTL3_EV_vs_WT_F09.06779.06779.2 0.0133 Mar-32 K.SNPSAVAGNETPGASTK[136.11].G "sp|Q9UDY2|ZO2_HUMAN,tr|A0A2R8YDH4|A0A2R8YDH4_HUMAN,tr|A0A3B3IS03|A0A3B3IS03_HUMAN,tr|A0A1B0GTW1|A0A1B0GTW1_HUMAN,tr|A0A3B3ISZ5|A0A3B3ISZ5_HUMAN,tr|A0A3B3IRI3|A0A3B3IRI3_HUMAN,tr|A0A3B3ITE1|A0A3B3ITE1_HUMAN" 7 1594.7678 1.13 127846 6779 2 1594.775159 798.3912 Tight junction protein ZO-2 OS=Homo sapiens OX=9606 GN=TJP2 PE=1 SV=2 5.72 1701 - 23371.5 - - - 4.5963 - 0.824 0.397 - 14.7 1 2 0 0.0073 17 0 0 0 5.20E+06 4.61E+06 - - - 1.495 0.9849 221125_WJC_METTL3_EV_vs_WT_F09.06783.06783.3 0.00263 Oct-36 K.TK[136.11]SPFEQHIK[136.11].N sp|Q92520|FAM3C_HUMAN 1 1229.6739 0.89 127848 6783 3 1229.677438 410.8986 Protein FAM3C OS=Homo sapiens OX=9606 GN=FAM3C PE=1 SV=1 8.29 1701.6 - 224452 - - - 2.8593 - 1.485 0.327 - 122.5 1 2 1 0.0035 10 0 0 0 4.09E+06 4.59E+06 - - - 3.3395 0.9999 221125_WJC_METTL3_EV_vs_WT_F09.06785.06785.3 4.05E-07 17/52 R.RLAQDGAHVVVSSR.K "sp|Q9BTZ2|DHRS4_HUMAN,tr|F5GWZ1|F5GWZ1_HUMAN" 2 1493.8063 1.49 127850 6785 3 1493.810085 498.9427 Dehydrogenase\reductase SDR family member 4 OS=Homo sapiens OX=9606 GN=DHRS4 PE=1 SV=3 9.61 1701.9 - 264913 - - - 2.5519 - 2.935 0.516 - 371.2 1 2 0 0.0038 14 0 0 0 8.64E+07 5.80E+07 - - - 7.1532 0.9997 221125_WJC_METTL3_EV_vs_WT_F09.06786.06786.3 0.00255 18/52 R.R[166.11]LAQDGAHVVVSSR[166.11].K "sp|Q9BTZ2|DHRS4_HUMAN,tr|F5GWZ1|F5GWZ1_HUMAN" 2 1513.8228 1.49 127851 6786 3 1513.829161 505.6149 Dehydrogenase\reductase SDR family member 4 OS=Homo sapiens OX=9606 GN=DHRS4 PE=1 SV=3 9.61 1702 - 249627 - - - 4.1934 - 2.713 0.486 - 368.9 1 2 0 0.0063 14 0 0 0 8.64E+07 5.80E+07 - - - 6.609 0.9406 221125_WJC_METTL3_EV_vs_WT_F09.06788.06788.3 0.137 Jul-56 R.SYSC[160.03]QVTHEGSTVEK.T "sp|B9A064|IGLL5_HUMAN,sp|P0CG04|IGLC1_HUMAN,sp|P0DOY2|IGLC2_HUMAN,sp|P0DOY3|IGLC3_HUMAN,sp|P0CF74|IGLC6_HUMAN,tr|A0A5H1ZRQ4|A0A5H1ZRQ4_HUMAN,tr|A0A0B4J231|A0A0B4J231_HUMAN" 7 1710.7519 999 127853 6788 3 1710.756654 571.2579 Immunoglobulin lambda-like polypeptide 5 OS=Homo sapiens OX=9606 GN=IGLL5 PE=2 SV=2 5.38 1702.3 - 114473 - - - 2.7707 - 1.025 0.253 - 27.3 1 2 0 0.0047 15 0 0 0 4.06E+06 0.00E+00 - - - 1.4238 1 221125_WJC_METTL3_EV_vs_WT_F09.06794.06794.3 2.78E-05 Nov-52 K.SIEEQQKPLTDSQR.V sp|Q9UKV8|AGO2_HUMAN 1 1657.8271 2.28 127857 6794 3 1657.829621 553.6163 Protein argonaute-2 OS=Homo sapiens OX=9606 GN=AGO2 PE=1 SV=3 4.68 1703 - 353898 - - - 1.5038 - 2.265 0.54 - 113.8 1 2 0 0.0025 14 0 0 0 1.99E+07 8.76E+06 - - - 6.7325 0.9998 221125_WJC_METTL3_EV_vs_WT_F09.06795.06795.2 1.44E-05 24-Nov K.KAEGEPQEESPLK.S "sp|Q9NYF8|BCLF1_HUMAN,tr|E9PKI6|E9PKI6_HUMAN,tr|A0A1W2PQ43|A0A1W2PQ43_HUMAN,tr|E9PK91|E9PK91_HUMAN,tr|E9PJA7|E9PJA7_HUMAN,tr|E9PK09|E9PK09_HUMAN,tr|E9PQN2|E9PQN2_HUMAN" 7 1440.7096 3.06 127858 6795 2 1440.712961 721.3621 Bcl-2-associated transcription factor 1 OS=Homo sapiens OX=9606 GN=BCLAF1 PE=1 SV=2 4.49 1703.1 - 183231 - - - 2.3058 - 2.502 0.572 - 359.4 1 2 0 0.0033 13 0 0 0 1.87E+07 6.12E+06 - - - 5.6185 0.9998 221125_WJC_METTL3_EV_vs_WT_F09.06796.06796.3 7.86E-05 Dec-52 K.SIEEQQK[136.11]PLTDSQR[166.11].V sp|Q9UKV8|AGO2_HUMAN 1 1675.8496 2.38 127859 6796 3 1675.855759 559.6238 Protein argonaute-2 OS=Homo sapiens OX=9606 GN=AGO2 PE=1 SV=3 4.68 1703.3 - 207682 - - - 3.6763 - 2.063 0.561 - 119.5 1 2 0 0.0062 14 0 0 0 2.11E+07 8.83E+06 - - - 6.7174 0.9886 221125_WJC_METTL3_EV_vs_WT_F09.06797.06797.3 0.0121 Aug-32 R.EELDKEFKK.K "sp|Q9BX40|LS14B_HUMAN,tr|Q5TBP9|Q5TBP9_HUMAN" 2 1164.6027 1.1 127860 6797 3 1164.607228 389.2082 Protein LSM14 homolog B OS=Homo sapiens OX=9606 GN=LSM14B PE=1 SV=1 4.87 1703.4 - 172111 - - - 3.9275 - 1.855 0.336 - 81.4 1 2 1 0.0046 9 0 0 0 3.35E+06 3.04E+06 - - - 4.147 0.9995 221125_WJC_METTL3_EV_vs_WT_F09.06798.06798.2 0.000512 22-Aug K.VGGTSDVEVNEK.K "sp|P10809|CH60_HUMAN,tr|A0A7I2V2X6|A0A7I2V2X6_HUMAN,tr|A0A7I2YQK6|A0A7I2YQK6_HUMAN,tr|A0A7I2V599|A0A7I2V599_HUMAN" 4 1232.5885 1.41 127861 6798 2 1232.591527 617.3015 "60 kDa heat shock protein, mitochondrial OS=Homo sapiens OX=9606 GN=HSPD1 PE=1 SV=2" 4.14 1703.5 - 63822.6 - - - 2.4874 - 1.968 0.474 - 305.5 1 2 0 0.0031 12 0 0 0 2.32E+07 1.65E+07 - - - 4.3223 0.9997 221125_WJC_METTL3_EV_vs_WT_F09.06799.06799.2 7.52E-06 24-Aug K.K[136.11]AEGEPQEESPLK[136.11].S "sp|Q9NYF8|BCLF1_HUMAN,tr|E9PKI6|E9PKI6_HUMAN,tr|A0A1W2PQ43|A0A1W2PQ43_HUMAN,tr|E9PK91|E9PK91_HUMAN,tr|E9PJA7|E9PJA7_HUMAN,tr|E9PK09|E9PK09_HUMAN,tr|E9PQN2|E9PQN2_HUMAN" 7 1456.738 3.06 127862 6799 2 1456.741721 729.3763 Bcl-2-associated transcription factor 1 OS=Homo sapiens OX=9606 GN=BCLAF1 PE=1 SV=2 4.49 1703.7 - 63496.1 - - - 2.5276 - 1.831 0.648 - 173.9 1 2 0 0.0037 13 0 0 0 1.87E+07 6.12E+06 - - - 5.3784 0.9968 221125_WJC_METTL3_EV_vs_WT_F09.06801.06801.3 0.00268 May-60 K.MNKSEDDESGAGELTR.E sp|P33993|MCM7_HUMAN 1 1737.7476 0.97 127863 6801 3 1737.74469 580.2565 DNA replication licensing factor MCM7 OS=Homo sapiens OX=9606 GN=MCM7 PE=1 SV=4 4.18 1703.9 - 59754.8 - - - -1.6498 - 1.153 0.443 - 31.4 1 2 1 -0.0029 16 0 0 0 1.44E+06 1.48E+06 - - - 3.8435 1 221125_WJC_METTL3_EV_vs_WT_F09.06805.06805.2 1.36E-06 22-Nov K.VGGTSDVEVNEK[136.11].K "sp|P10809|CH60_HUMAN,tr|A0A7I2V2X6|A0A7I2V2X6_HUMAN,tr|A0A7I2YQK6|A0A7I2YQK6_HUMAN,tr|A0A7I2V599|A0A7I2V599_HUMAN" 4 1240.6027 1.43 127865 6805 2 1240.605877 621.3086 "60 kDa heat shock protein, mitochondrial OS=Homo sapiens OX=9606 GN=HSPD1 PE=1 SV=2" 4.14 1704.5 - 183044 - - - 2.5923 - 2.586 0.617 - 586.3 1 2 0 0.0032 12 0 0 0 2.32E+07 1.62E+07 - - - 6.0971 1 221125_WJC_METTL3_EV_vs_WT_F09.06806.06806.3 6.40E-07 Oct-64 R.LGEEVNGEATESQQKPR.N sp|Q9NVH0|EXD2_HUMAN 1 1870.9021 0.95 127866 6806 3 1870.905482 624.6413 Exonuclease 3'-5' domain-containing protein 2 OS=Homo sapiens OX=9606 GN=EXD2 PE=1 SV=2 4.49 1704.6 - 124259 - - - 1.8162 - 2.138 0.562 - 83.5 1 2 0 0.0034 17 0 0 0 4.18E+06 4.41E+06 - - - 6.7245 0.9999 221125_WJC_METTL3_EV_vs_WT_F09.06807.06807.3 9.08E-07 Dec-60 R.K[136.11]EASDPQPEEADGGLK[136.11].S sp|P52907|CAZA1_HUMAN 1 1685.8079 1.44 127867 6807 3 1685.811884 562.9432 F-actin-capping protein subunit alpha-1 OS=Homo sapiens OX=9606 GN=CAPZA1 PE=1 SV=3 4.18 1704.7 - 302428 - - - 2.3579 - 2.46 0.544 - 162.2 1 2 0 0.004 16 0 0 0 6.41E+06 4.45E+06 - - - 6.9137 0.7714 221125_WJC_METTL3_EV_vs_WT_F09.06808.06808.2 1.67 20-May K.IGSGFFSEVFK.V "sp|Q96S53|TESK2_HUMAN,tr|A0A5F9ZGZ0|A0A5F9ZGZ0_HUMAN" 2 1216.6128 0.57 127868 6808 2 1216.607948 609.3137 Dual specificity testis-specific protein kinase 2 OS=Homo sapiens OX=9606 GN=TESK2 PE=1 SV=1 6 1704.9 - 252206 - - - -4.0087 - 0.894 0.155 - 54.2 1 2 0 -0.0049 11 0 0 0 2.68E+06 4.67E+06 - - - -0.1188 0.9975 221125_WJC_METTL3_EV_vs_WT_F09.06814.06814.2 0.00169 Jun-32 R.NAAPPPSNTEAPPGETR.T "sp|Q9GZR7|DDX24_HUMAN,tr|A0A1W2PRR2|A0A1W2PRR2_HUMAN,tr|F5GYL3|F5GYL3_HUMAN,tr|G3V529|G3V529_HUMAN" 4 1704.8067 1.46 127874 6814 2 1704.807444 853.4106 ATP-dependent RNA helicase DDX24 OS=Homo sapiens OX=9606 GN=DDX24 PE=1 SV=1 4.53 1705.6 - 41822.4 - - - 0.4206 - 1.035 0.345 - 68.2 1 2 0 0.0007 17 0 0 0 6.50E+05 4.46E+05 - - - 1.6735 0.9995 221125_WJC_METTL3_EV_vs_WT_F09.06816.06816.3 0.000288 14/52 R.TSKEPPSSPLQPQK.E "sp|Q92615|LAR4B_HUMAN,tr|A0A087X183|A0A087X183_HUMAN,tr|H0Y4V9|H0Y4V9_HUMAN" 3 1522.7991 1.37 127875 6816 3 1522.79754 508.607 La-related protein 4B OS=Homo sapiens OX=9606 GN=LARP4B PE=1 SV=3 8.26 1706 - 731861 - - - -1.0389 - 2.344 0.39 - 248.2 1 2 1 -0.0016 14 0 0 0 2.02E+07 1.48E+07 - - - 5.1515 1 221125_WJC_METTL3_EV_vs_WT_F09.06818.06818.3 7.39E-09 17/64 R.LGEEVNGEATESQQK[136.11]PR[166.11].N sp|Q9NVH0|EXD2_HUMAN 1 1888.9246 0.95 127876 6818 3 1888.926696 630.6488 Exonuclease 3'-5' domain-containing protein 2 OS=Homo sapiens OX=9606 GN=EXD2 PE=1 SV=2 4.49 1706.2 - 288792 - - - 1.134 - 3.593 0.631 - 406.9 1 2 0 0.0021 17 0 0 0 4.18E+06 4.41E+06 - - - 8.8055 0.9954 221125_WJC_METTL3_EV_vs_WT_F09.06820.06820.3 0.0139 15/48 K.IQDK[136.11]EGIPPDQQR[166.11].L "sp|P62979|RS27A_HUMAN,sp|P0CG48|UBC_HUMAN,sp|P0CG48|UBC_HUMAN,sp|P0CG48|UBC_HUMAN,sp|P0CG48|UBC_HUMAN,sp|P0CG48|UBC_HUMAN,sp|P0CG48|UBC_HUMAN,sp|P0CG48|UBC_HUMAN,sp|P0CG48|UBC_HUMAN,sp|P0CG48|UBC_HUMAN,sp|P0CG47|UBB_HUMAN,sp|P0CG47|UBB_HUMAN,sp|P0CG47|UBB_HUMAN,sp|P62987|RL40_HUMAN,tr|F5H388|F5H388_HUMAN,tr|F5H388|F5H388_HUMAN,tr|F5GYU3|F5GYU3_HUMAN,tr|F5GYU3|F5GYU3_HUMAN,tr|B4DV12|B4DV12_HUMAN,tr|B4DV12|B4DV12_HUMAN,tr|J3QSA3|J3QSA3_HUMAN,tr|Q5PY61|Q5PY61_HUMAN,tr|Q5PY61|Q5PY61_HUMAN,tr|Q5PY61|Q5PY61_HUMAN,tr|F5H2Z3|F5H2Z3_HUMAN,tr|F5H2Z3|F5H2Z3_HUMAN,tr|M0R2S1|M0R2S1_HUMAN,tr|J3QS39|J3QS39_HUMAN,tr|J3QTR3|J3QTR3_HUMAN,tr|Q96C32|Q96C32_HUMAN,tr|Q96C32|Q96C32_HUMAN,tr|Q96C32|Q96C32_HUMAN,tr|Q96C32|Q96C32_HUMAN,tr|M0R1V7|M0R1V7_HUMAN,tr|F5H747|F5H747_HUMAN,tr|F5H747|F5H747_HUMAN,tr|F5GXK7|F5GXK7_HUMAN,tr|F5GXK7|F5GXK7_HUMAN,tr|M0R1M6|M0R1M6_HUMAN,tr|F5H6Q2|F5H6Q2_HUMAN,tr|F5H6Q2|F5H6Q2_HUMAN,tr|F5GZ39|F5GZ39_HUMAN,tr|J3QKN0|J3QKN0_HUMAN,tr|J3QKN0|J3QKN0_HUMAN,tr|F5H265|F5H265_HUMAN,tr|F5H265|F5H265_HUMAN,tr|A0A2R8Y422|A0A2R8Y422_HUMAN" 47 1540.7964 0.07 127878 6820 3 1540.793665 514.6061 Ubiquitin-40S ribosomal protein S27a OS=Homo sapiens OX=9606 GN=RPS27A PE=1 SV=2 4.56 1706.4 - 547149 - - - -1.801 - 2.203 0.266 - 360.7 1 2 1 -0.0028 13 0 0 0 8.39E+05 1.12E+07 - - - 3.6463 0.9999 221125_WJC_METTL3_EV_vs_WT_F09.06825.06825.2 4.32E-06 Oct-32 K.SNPSAVAGNETPGASTK.G "sp|Q9UDY2|ZO2_HUMAN,tr|A0A2R8YDH4|A0A2R8YDH4_HUMAN,tr|A0A3B3IS03|A0A3B3IS03_HUMAN,tr|A0A1B0GTW1|A0A1B0GTW1_HUMAN,tr|A0A3B3ISZ5|A0A3B3ISZ5_HUMAN,tr|A0A3B3IRI3|A0A3B3IRI3_HUMAN,tr|A0A3B3ITE1|A0A3B3ITE1_HUMAN" 7 1586.7536 1.13 127883 6825 2 1586.756003 794.3841 Tight junction protein ZO-2 OS=Homo sapiens OX=9606 GN=TJP2 PE=1 SV=2 5.72 1707.1 - 169406 - - - 1.4961 - 2.339 0.597 - 218.7 1 2 0 0.0024 17 0 0 0 5.20E+06 4.61E+06 - - - 5.5388 0.9712 221125_WJC_METTL3_EV_vs_WT_F09.06826.06826.3 0.0429 Jul-48 K.DER[166.11]QEDPYGPQTK[136.11].E sp|O15226|NKRF_HUMAN 1 1579.7233 1.09 127884 6826 3 1579.720839 527.5817 NF-kappa-B-repressing factor OS=Homo sapiens OX=9606 GN=NKRF PE=1 SV=2 4.32 1707.2 - 104586 - - - -1.58 - 1.316 0.268 - 65.8 1 2 1 -0.0025 13 0 0 0 1.51E+06 1.38E+06 - - - 2.2718 0.9999 221125_WJC_METTL3_EV_vs_WT_F09.06833.06833.3 1.12E-05 14/56 R.HVAAGTQQPYTDGVR.M sp|P14923|PLAK_HUMAN 1 1598.7801 2.18 127889 6833 3 1598.783651 533.934 Junction plakoglobin OS=Homo sapiens OX=9606 GN=JUP PE=1 SV=3 6.74 1708.2 - 480931 - - - 2.2098 - 2.553 0.482 - 312.1 1 2 0 0.0035 15 0 0 0 1.38E+07 6.32E+06 - - - 6.3585 0.968 221125_WJC_METTL3_EV_vs_WT_F09.06840.06840.3 0.00375 Dec-44 A.NTLAEK[136.11]DEFEHK[136.11].R "sp|P0DMV8|HS71A_HUMAN,sp|P0DMV9|HS71B_HUMAN,tr|V9GZ37|V9GZ37_HUMAN,tr|A0A0G2JIW1|A0A0G2JIW1_HUMAN" 4 1475.7227 0.11 127894 6840 3 1475.725969 492.9149 Heat shock 70 kDa protein 1A OS=Homo sapiens OX=9606 GN=HSPA1A PE=1 SV=1 4.83 1709.1 - 861783 - - - 2.1996 - 2.472 0.486 - 197.6 1 1 1 0.0032 12 0 0 0 2.65E+06 2.37E+07 - - - 6.4661 0.9967 221125_WJC_METTL3_EV_vs_WT_F09.06841.06841.3 0.0251 Nov-36 K.TKSPFEQHIK.N sp|Q92520|FAM3C_HUMAN 1 1213.6455 0.83 127895 6841 3 1213.647094 405.5558 Protein FAM3C OS=Homo sapiens OX=9606 GN=FAM3C PE=1 SV=1 8.29 1709.2 - 273978 - - - 1.2953 - 1.987 0.286 - 156.4 1 2 1 0.0016 10 0 0 0 5.04E+06 6.07E+06 - - - 3.7334 0.9993 221125_WJC_METTL3_EV_vs_WT_F09.06847.06847.3 0.000101 16/36 R.RREEEGIQLR.K "sp|O60684|IMA7_HUMAN,sp|O15131|IMA6_HUMAN,sp|P52294|IMA5_HUMAN,tr|C9JWD9|C9JWD9_HUMAN,tr|S4R3E5|S4R3E5_HUMAN,tr|C9JYI4|C9JYI4_HUMAN,tr|C9J352|C9J352_HUMAN,tr|C9J4U1|C9J4U1_HUMAN,tr|F2Z3G4|F2Z3G4_HUMAN,tr|Q5TD90|Q5TD90_HUMAN" 10 1284.6898 0.84 127900 6847 3 1284.692461 429.2372 Importin subunit alpha-7 OS=Homo sapiens OX=9606 GN=KPNA6 PE=1 SV=1 6.23 1710 - 1.26E+06 - - - 2.0347 - 2.471 0.385 - 335 1 2 1 0.0026 10 0 0 0 2.94E+07 3.51E+07 - - - 5.4735 1 221125_WJC_METTL3_EV_vs_WT_F09.06848.06848.3 6.16E-07 15/36 K.HTNYTMEHIR.V "sp|O43707|ACTN4_HUMAN,sp|P35609|ACTN2_HUMAN,sp|P12814|ACTN1_HUMAN,tr|A0A804HK61|A0A804HK61_HUMAN,tr|H7C5W8|H7C5W8_HUMAN,tr|A0A804HJU8|A0A804HJU8_HUMAN,tr|A0A804HIN7|A0A804HIN7_HUMAN,tr|H0YJ11|H0YJ11_HUMAN,tr|A0A494C060|A0A494C060_HUMAN,tr|H9KV75|H9KV75_HUMAN,tr|A0A804HLF4|A0A804HLF4_HUMAN,tr|H0YJW3|H0YJW3_HUMAN,tr|A0A7I2V4Y4|A0A7I2V4Y4_HUMAN,tr|A0A804HII9|A0A804HII9_HUMAN,tr|A0A804HL31|A0A804HL31_HUMAN,tr|A0A494C1A0|A0A494C1A0_HUMAN,tr|F5GXS2|F5GXS2_HUMAN,tr|A0A804HI95|A0A804HI95_HUMAN,tr|A0A804HKE2|A0A804HKE2_HUMAN,tr|A0A804HLD0|A0A804HLD0_HUMAN,tr|H7C144|H7C144_HUMAN" 21 1300.5983 1.12 127901 6848 3 1300.600808 434.54 Alpha-actinin-4 OS=Homo sapiens OX=9606 GN=ACTN4 PE=1 SV=2 6.92 1710.1 - 683590 - - - 1.9637 - 2.915 0.552 - 343.8 1 2 0 0.0026 10 0 0 0 1.43E+07 1.28E+07 - - - 7.818 0.9996 221125_WJC_METTL3_EV_vs_WT_F09.06853.06853.3 0.0285 13/44 K.SKAEAESLYQSK.Y sp|P04264|K2C1_HUMAN 1 1339.662 930.79 127904 6853 3 1339.664948 447.5613 "Keratin, type II cytoskeletal 1 OS=Homo sapiens OX=9606 GN=KRT1 PE=1 SV=6" 5.86 1710.8 - 9.03E+06 - - - 2.2304 - 2.653 0.449 - 305.4 1 2 1 0.003 12 0 0 0 9.04E+08 9.71E+05 - - - 6.2495 1 221125_WJC_METTL3_EV_vs_WT_F09.06855.06855.3 0.0199 16/44 K.R[166.11]QLEEAEEEAQR[166.11].A sp|P35579|MYH9_HUMAN 1 1506.7177 1.61 127906 6855 3 1506.719836 503.2465 Myosin-9 OS=Homo sapiens OX=9606 GN=MYH9 PE=1 SV=4 4.33 1711 - 2.08E+06 - - - 1.3918 - 3.093 0.434 - 649.5 1 2 0 0.0021 12 0 0 0 4.59E+07 2.85E+07 - - - 6.5079 0.9985 221125_WJC_METTL3_EV_vs_WT_F09.06856.06856.2 0.00432 24-Sep K.EQSSSSFSQGQSS.- sp|P08779|K1C16_HUMAN 1 1344.543 - 127907 6856 2 1344.545283 673.2788 "Keratin, type I cytoskeletal 16 OS=Homo sapiens OX=9606 GN=KRT16 PE=1 SV=4" 4 1711 - 1.39E+06 - - - 1.7225 - 1.268 0.398 - 141.3 1 2 0 0.0023 13 0 0 0 - - - - - 2.5893 1 221125_WJC_METTL3_EV_vs_WT_F09.06857.06857.2 1.86E-09 18/22 K.SKAEAESLYQSK.Y sp|P04264|K2C1_HUMAN 1 1339.662 999 127908 6857 2 1339.663332 670.8383 "Keratin, type II cytoskeletal 1 OS=Homo sapiens OX=9606 GN=KRT1 PE=1 SV=6" 5.86 1711.1 - 1.33E+06 - - - 1.0241 - 3.135 0.661 - 792.9 1 2 1 0.0014 12 0 0 0 1.83E+08 0.00E+00 - - - 6.9292 0.9974 221125_WJC_METTL3_EV_vs_WT_F09.06872.06872.2 0.0107 24-Aug K.VEQATKPSFESGR.R "sp|P38159|RBMX_HUMAN,tr|H3BT71|H3BT71_HUMAN,tr|H0Y6E7|H0Y6E7_HUMAN" 3 1434.7103 1.57 127919 6872 2 1434.716741 718.3624 "RNA-binding motif protein, X chromosome OS=Homo sapiens OX=9606 GN=RBMX PE=1 SV=3" 6.11 1713.1 - 174795 - - - 4.4845 - 1.971 0.454 - 143 1 2 0 0.0064 13 0 0 0 3.96E+06 2.52E+06 - - - 4.1337 0.9991 221125_WJC_METTL3_EV_vs_WT_F09.06881.06881.3 0.000257 17/36 R.R[166.11]R[166.11]EEEGIQLR[166.11].K "sp|O60684|IMA7_HUMAN,sp|O15131|IMA6_HUMAN,sp|P52294|IMA5_HUMAN,tr|C9JWD9|C9JWD9_HUMAN,tr|S4R3E5|S4R3E5_HUMAN,tr|C9JYI4|C9JYI4_HUMAN,tr|C9J352|C9J352_HUMAN,tr|C9J4U1|C9J4U1_HUMAN,tr|F2Z3G4|F2Z3G4_HUMAN,tr|Q5TD90|Q5TD90_HUMAN" 10 1314.7147 0.84 127924 6881 3 1314.715928 439.2455 Importin subunit alpha-7 OS=Homo sapiens OX=9606 GN=KPNA6 PE=1 SV=1 6.23 1714.3 - 1.29E+06 - - - 0.9667 - 2.35 0.328 - 357.4 1 2 1 0.0013 10 0 0 0 2.93E+07 3.48E+07 - - - 4.6918 0.9999 221125_WJC_METTL3_EV_vs_WT_F09.06884.06884.3 1.13E-06 Sep-64 R.GGDGGERDEDGDALAER.E sp|Q8N8J7|F241A_HUMAN 1 1717.7139 1.11 127927 6884 3 1717.715441 573.5786 Uncharacterized protein FAM241A OS=Homo sapiens OX=9606 GN=FAM241A PE=2 SV=2 3.9 1714.7 - 161467 - - - 0.8686 - 2.123 0.6 - 98.7 1 2 1 0.0015 17 0 0 0 2.12E+06 1.91E+06 - - - 7.1309 0.9997 221125_WJC_METTL3_EV_vs_WT_F09.06891.06891.3 0.00516 Aug-44 K.LNGHQLENHALK.V sp|Q9NZI8|IF2B1_HUMAN 1 1372.7211 3.71 127933 6891 3 1372.721061 458.581 Insulin-like growth factor 2 mRNA-binding protein 1 OS=Homo sapiens OX=9606 GN=IGF2BP1 PE=1 SV=2 6.92 1715.7 - 1.67E+06 - - - -0.0626 - 1.767 0.373 - 67.6 1 2 0 -0.0001 12 0 0 0 8.71E+07 2.35E+07 - - - 4.2765 0.9989 221125_WJC_METTL3_EV_vs_WT_F09.06895.06895.3 0.000452 Sep-48 R.DGTSSQHAENLVR.N "sp|Q8WVS4|DC2I1_HUMAN,tr|H7C022|H7C022_HUMAN" 2 1412.6644 1.36 127937 6895 3 1412.669502 471.8954 Cytoplasmic dynein 2 intermediate chain 1 OS=Homo sapiens OX=9606 GN=DYNC2I1 PE=1 SV=3 5.32 1716.1 - 451753 - - - 3.5975 - 1.776 0.406 - 116.7 1 2 0 0.0051 13 0 0 0 8.13E+06 5.97E+06 - - - 4.6224 1 221125_WJC_METTL3_EV_vs_WT_F09.06896.06896.3 5.66E-08 17/56 K.DQEPK[136.11]PSPEPAAVSR[166.11].G sp|Q9H7S9|ZN703_HUMAN 1 1624.8176 1.74 127938 6896 3 1624.816842 542.6131 Zinc finger protein 703 OS=Homo sapiens OX=9606 GN=ZNF703 PE=1 SV=1 4.68 1716.2 - 313534 - - - -0.4481 - 3.098 0.572 - 332.1 1 2 0 -0.0007 15 0 0 0 1.19E+09 6.86E+08 - - - 7.8676 1 221125_WJC_METTL3_EV_vs_WT_F09.06902.06902.3 4.68E-08 20/64 K.AGYSTDESSSSSLHATR[166.11].T sp|P51116|FXR2_HUMAN 1 1764.779 1.49 127942 6902 3 1764.779485 589.2669 Fragile X mental retardation syndrome-related protein 2 OS=Homo sapiens OX=9606 GN=FXR2 PE=1 SV=2 5.32 1717 - 476858 - - - 0.272 - 3.723 0.697 - 298.8 1 2 0 0.0005 17 0 0 0 1.56E+07 1.04E+07 - - - 9.6316 1 221125_WJC_METTL3_EV_vs_WT_F09.06905.06905.3 0.0191 21/44 K.R[166.11]LQIEESSK[136.11]PVR[166.11].L sp|P13984|T2FB_HUMAN 1 1468.8356 3.15 127945 6905 3 1468.835865 490.6191 General transcription factor IIF subunit 2 OS=Homo sapiens OX=9606 GN=GTF2F2 PE=1 SV=2 8.75 1717.4 - 560066 - - - 0.1695 - 3.63 0.499 - 858.8 1 2 0 0.0002 12 0 0 0 3.00E+07 9.54E+06 - - - 7.6769 0.9999 221125_WJC_METTL3_EV_vs_WT_F09.06906.06906.3 2.89E-06 Dec-52 K.IYPSRDEYEAHQER.V "sp|Q99496|RING2_HUMAN,tr|X6RFN3|X6RFN3_HUMAN" 2 1791.8176 1.76 127946 6906 3 1791.817196 598.2798 E3 ubiquitin-protein ligase RING2 OS=Homo sapiens OX=9606 GN=RNF2 PE=1 SV=1 4.83 1717.6 - 495868 - - - -0.24 - 2.016 0.551 - 121.9 1 2 1 -0.0004 14 0 0 0 4.21E+07 2.39E+07 - - - 6.5462 0.9271 221125_WJC_METTL3_EV_vs_WT_F09.06907.06907.3 0.00733 Nov-48 R.R[166.11]GSC[160.03]VSPYSSRC[160.03]R[166.11].A tr|X6R5I7|X6R5I7_HUMAN 1 1590.7258 - 127947 6907 3 1590.714418 531.2492 Regulator of telomere elongation helicase 1 (Fragment) OS=Homo sapiens OX=9606 GN=RTEL1 PE=4 SV=1 9.69 1717.7 - 424147 - - - -7.1672 - 2.119 0.356 - 84.3 2 2 1 -0.0114 13 0 0 0 - - - - - 4.4026 0.9999 221125_WJC_METTL3_EV_vs_WT_F09.06911.06911.3 3.15E-05 Sep-48 R.DGTSSQHAENLVR[166.11].N "sp|Q8WVS4|DC2I1_HUMAN,tr|H7C022|H7C022_HUMAN" 2 1422.6727 1.56 127949 6911 3 1422.671149 475.2315 Cytoplasmic dynein 2 intermediate chain 1 OS=Homo sapiens OX=9606 GN=DYNC2I1 PE=1 SV=3 5.32 1718.2 - 460537 - - - -1.0832 - 1.972 0.45 - 103.7 1 2 0 -0.0015 13 0 0 0 8.10E+06 5.18E+06 - - - 5.3977 0.9999 221125_WJC_METTL3_EV_vs_WT_F09.06913.06913.3 4.91E-05 14/56 K.DQEPKPSPEPAAVSR.G sp|Q9H7S9|ZN703_HUMAN 1 1606.7951 1.74 127951 6913 3 1606.796169 536.6056 Zinc finger protein 703 OS=Homo sapiens OX=9606 GN=ZNF703 PE=1 SV=1 4.68 1718.4 - 3.17E+06 - - - 0.6653 - 2.15 0.462 - 221.6 1 2 0 0.0011 15 0 0 0 1.20E+09 6.88E+08 - - - 5.6879 0.9994 221125_WJC_METTL3_EV_vs_WT_F09.06914.06914.3 0.00223 Nov-56 K.SPTPPPSSK[136.11]PSSIPR[166.11].K "sp|Q8NEM7|SP20H_HUMAN,tr|B4E2D5|B4E2D5_HUMAN,tr|R4GND2|R4GND2_HUMAN,tr|H7C5F9|H7C5F9_HUMAN,tr|F6S7C4|F6S7C4_HUMAN" 5 1551.8376 1.47 127952 6914 3 1551.840899 518.2865 Transcription factor SPT20 homolog OS=Homo sapiens OX=9606 GN=SUPT20H PE=1 SV=2 11 1718.5 - 288240 - - - 2.1407 - 1.967 0.352 - 134.5 1 2 0 0.0033 15 0 0 0 7.52E+07 5.13E+07 - - - 4.2288 0.9999 221125_WJC_METTL3_EV_vs_WT_F09.06915.06915.2 2.03E-07 24-Dec K.DETGELSSADEKR.Y sp|Q92900|RENT1_HUMAN 1 1435.6427 2.69 127953 6915 2 1435.643784 718.8286 Regulator of nonsense transcripts 1 OS=Homo sapiens OX=9606 GN=UPF1 PE=1 SV=2 4.18 1718.7 - 142763 - - - 0.7683 - 2.571 0.509 - 520.9 1 2 0 0.0011 13 0 0 0 1.70E+06 6.32E+05 - - - 5.2237 0.9857 221125_WJC_METTL3_EV_vs_WT_F09.06918.06918.3 0.00918 15/44 R.SATREPPYRVPR.D "sp|P43243|MATR3_HUMAN,tr|A8MXP9|A8MXP9_HUMAN,tr|D6R991|D6R991_HUMAN,tr|A0A0R4J2E8|A0A0R4J2E8_HUMAN,tr|D6REM6|D6REM6_HUMAN" 5 1427.7633 0.85 127954 6918 3 1427.761382 476.9284 Matrin-3 OS=Homo sapiens OX=9606 GN=MATR3 PE=1 SV=2 10.74 1719.1 - 660626 - - - -1.3756 - 1.668 0.242 - 195.5 1 2 2 -0.002 12 0 0 0 7.51E+07 8.84E+07 - - - 2.6557 0.9981 221125_WJC_METTL3_EV_vs_WT_F09.06920.06920.4 2.96E-05 14/78 K.IYPSR[166.11]DEYEAHQER[166.11].V "sp|Q99496|RING2_HUMAN,tr|X6RFN3|X6RFN3_HUMAN" 2 1811.8342 1.64 127956 6920 4 1811.83268 453.9658 E3 ubiquitin-protein ligase RING2 OS=Homo sapiens OX=9606 GN=RNF2 PE=1 SV=1 4.83 1719.2 - 1.90E+06 - - - -0.8202 - 2.353 0.328 - 135 1 2 1 -0.0015 14 0 0 0 6.67E+07 4.08E+07 - - - 2.3919 0.9984 221125_WJC_METTL3_EV_vs_WT_F09.06921.06921.3 0.1 13/56 K.SPTPPPSSKPSSIPR.K "sp|Q8NEM7|SP20H_HUMAN,tr|B4E2D5|B4E2D5_HUMAN,tr|R4GND2|R4GND2_HUMAN,tr|H7C5F9|H7C5F9_HUMAN,tr|F6S7C4|F6S7C4_HUMAN" 5 1533.8151 1.46 127957 6921 3 1533.816046 512.279 Transcription factor SPT20 homolog OS=Homo sapiens OX=9606 GN=SUPT20H PE=1 SV=2 11 1719.4 - 418603 - - - 0.6122 - 1.886 0.25 - 185.5 1 2 0 0.0009 15 0 0 0 7.52E+07 5.16E+07 - - - 2.9825 0.97 221125_WJC_METTL3_EV_vs_WT_F09.06922.06922.2 0.346 28-May K.DQEPK[136.11]PSPEPAAVSR[166.11].G sp|Q9H7S9|ZN703_HUMAN 1 1624.8176 1.78 127958 6922 2 1624.812337 813.4161 Zinc finger protein 703 OS=Homo sapiens OX=9606 GN=ZNF703 PE=1 SV=1 4.68 1719.5 - 127393 - - - -3.2207 - 0.983 0.27 - 47.2 1 2 0 -0.0052 15 0 0 0 4.84E+07 2.73E+07 - - - 0.9914 0.9999 221125_WJC_METTL3_EV_vs_WT_F09.06926.06926.3 1.41E-05 Dec-48 R.DGTSSQHAENLVR.N "sp|Q8WVS4|DC2I1_HUMAN,tr|H7C022|H7C022_HUMAN" 2 1412.6644 1.56 127960 6926 3 1412.662332 471.8954 Cytoplasmic dynein 2 intermediate chain 1 OS=Homo sapiens OX=9606 GN=DYNC2I1 PE=1 SV=3 5.32 1720 - 460271 - - - -1.4781 - 1.905 0.436 - 225 1 2 0 -0.0021 13 0 0 0 8.10E+06 5.18E+06 - - - 5.1478 0.9999 221125_WJC_METTL3_EV_vs_WT_F09.06936.06936.2 5.58E-07 13/28 K.ELHSTPNGLSSESSR.K "sp|Q8N5Z5|KCD17_HUMAN,tr|A0A087WX35|A0A087WX35_HUMAN,tr|H0Y731|H0Y731_HUMAN" 3 1599.7489 5.01 127968 6936 2 1599.746617 800.8817 BTB\POZ domain-containing protein KCTD17 OS=Homo sapiens OX=9606 GN=KCTD17 PE=1 SV=3 5.4 1721.3 - 765568 - - - -1.4133 - 2.235 0.582 - 386.7 1 2 0 -0.0023 15 0 0 0 5.73E+07 1.14E+07 - - - 5.3162 1 221125_WJC_METTL3_EV_vs_WT_F09.06937.06937.3 3.01E-07 22/44 Y.PSRDEYEAHQER.V "sp|Q99496|RING2_HUMAN,tr|X6RFN3|X6RFN3_HUMAN" 2 1515.6702 1.57 127969 6937 3 1515.668897 506.2307 E3 ubiquitin-protein ligase RING2 OS=Homo sapiens OX=9606 GN=RNF2 PE=1 SV=1 4.83 1721.4 - 471444 - - - -0.8815 - 3.614 0.596 - 858.5 1 1 1 -0.0013 12 0 0 0 8.19E+06 5.21E+06 - - - 8.7458 0.9999 221125_WJC_METTL3_EV_vs_WT_F09.06938.06938.2 1.93E-05 28-Sep K.DQEPKPSPEPAAVSR.G sp|Q9H7S9|ZN703_HUMAN 1 1606.7951 1.78 127970 6938 2 1606.795141 804.4048 Zinc finger protein 703 OS=Homo sapiens OX=9606 GN=ZNF703 PE=1 SV=1 4.68 1721.6 - 360589 - - - 0.0255 - 1.853 0.576 - 155 1 2 0 0 15 0 0 0 4.84E+07 2.73E+07 - - - 4.8118 0.9969 221125_WJC_METTL3_EV_vs_WT_F09.06939.06939.3 0.00523 Aug-52 R.QSEVPKPEDGEPPR.R "sp|Q9Y520|PRC2C_HUMAN,tr|E7EPN9|E7EPN9_HUMAN" 2 1563.7529 1.19 127971 6939 3 1563.752061 522.2582 Protein PRRC2C OS=Homo sapiens OX=9606 GN=PRRC2C PE=1 SV=4 4.41 1721.7 - 184715 - - - -0.5365 - 1.527 0.257 - 64.3 1 2 0 -0.0008 14 0 0 0 9.75E+07 8.18E+07 - - - 2.53 1 221125_WJC_METTL3_EV_vs_WT_F09.06941.06941.3 3.18E-11 23/64 K.AGYSTDESSSSSLHATR.T sp|P51116|FXR2_HUMAN 1 1754.7707 1.49 127972 6941 3 1754.770998 585.9309 Fragile X mental retardation syndrome-related protein 2 OS=Homo sapiens OX=9606 GN=FXR2 PE=1 SV=2 5.32 1721.9 - 1.03E+06 - - - 0.1499 - 4.125 0.617 - 501.7 1 2 0 0.0003 17 0 0 0 1.55E+07 1.04E+07 - - - 8.9988 0.9998 221125_WJC_METTL3_EV_vs_WT_F09.06953.06953.3 0.00787 Nov-64 K.AQGPQQQPGSEGPSYAK[136.11].K "sp|Q3ZCQ8|TIM50_HUMAN,tr|M0R1Y4|M0R1Y4_HUMAN,tr|M0QXC3|M0QXC3_HUMAN,tr|M0R047|M0R047_HUMAN,tr|M0R303|M0R303_HUMAN,tr|M0R2D2|M0R2D2_HUMAN,tr|M0R003|M0R003_HUMAN,tr|M0R2Z3|M0R2Z3_HUMAN" 8 1736.8209 1.36 127982 6953 3 1736.818618 579.9476 Mitochondrial import inner membrane translocase subunit TIM50 OS=Homo sapiens OX=9606 GN=TIMM50 PE=1 SV=2 6.05 1723.4 - 204457 - - - -1.3294 - 2.071 0.387 - 163.6 1 2 0 -0.0023 17 0 0 0 3.32E+07 2.45E+07 - - - 4.6933 0.9996 221125_WJC_METTL3_EV_vs_WT_F09.06954.06954.2 7.02E-05 Sep-32 K.AQGPQQQPGSEGPSYAK.K "sp|Q3ZCQ8|TIM50_HUMAN,tr|M0R1Y4|M0R1Y4_HUMAN,tr|M0QXC3|M0QXC3_HUMAN,tr|M0R047|M0R047_HUMAN,tr|M0R303|M0R303_HUMAN,tr|M0R2D2|M0R2D2_HUMAN,tr|M0R003|M0R003_HUMAN,tr|M0R2Z3|M0R2Z3_HUMAN" 8 1728.8067 1.23 127983 6954 2 1728.811241 865.4106 Mitochondrial import inner membrane translocase subunit TIM50 OS=Homo sapiens OX=9606 GN=TIMM50 PE=1 SV=2 6.05 1723.5 - 175481 - - - 2.611 - 2.136 0.581 - 115 1 2 0 0.0045 17 0 0 0 3.90E+07 3.16E+07 - - - 5.1967 0.9995 221125_WJC_METTL3_EV_vs_WT_F09.06958.06958.3 0.000739 Nov-40 K.LK[136.11]GDDLQAIK[136.11]K[136.11].E "sp|P07910|HNRPC_HUMAN,tr|B4DY08|B4DY08_HUMAN,tr|G3V5V7|G3V5V7_HUMAN,tr|B2R5W2|B2R5W2_HUMAN,tr|G3V4C1|G3V4C1_HUMAN,tr|G3V576|G3V576_HUMAN,tr|G3V2D6|G3V2D6_HUMAN,tr|G3V4W0|G3V4W0_HUMAN,tr|G3V2Q1|G3V2Q1_HUMAN" 9 1251.7613 1.37 127985 6958 3 1251.759801 418.261 Heterogeneous nuclear ribonucleoproteins C1\C2 OS=Homo sapiens OX=9606 GN=HNRNPC PE=1 SV=4 8.5 1724 - 1.44E+06 - - - -1.1871 - 2.205 0.39 - 83.8 1 2 1 -0.0015 11 0 0 0 5.83E+08 4.25E+08 - - - 5.134 0.8767 221125_WJC_METTL3_EV_vs_WT_F09.06959.06959.3 0.00334 Sep-40 K.LKGDDLQAIKK.E "sp|P07910|HNRPC_HUMAN,tr|B4DY08|B4DY08_HUMAN,tr|G3V5V7|G3V5V7_HUMAN,tr|B2R5W2|B2R5W2_HUMAN,tr|G3V4C1|G3V4C1_HUMAN,tr|G3V576|G3V576_HUMAN,tr|G3V2D6|G3V2D6_HUMAN,tr|G3V4W0|G3V4W0_HUMAN,tr|G3V2Q1|G3V2Q1_HUMAN" 9 1227.7187 1.37 127986 6959 3 1227.718113 410.2468 Heterogeneous nuclear ribonucleoproteins C1\C2 OS=Homo sapiens OX=9606 GN=HNRNPC PE=1 SV=4 8.5 1724.1 - 1.31E+06 - - - -0.4675 - 1.653 0.107 - 67.5 1 2 1 -0.0006 11 0 0 0 5.83E+08 4.25E+08 - - - 1.1606 0.9999 221125_WJC_METTL3_EV_vs_WT_F09.06961.06961.3 0.0041 13/36 R.KGTFTDDLHK.L "sp|Q9H4A3|WNK1_HUMAN,sp|Q9Y3S1|WNK2_HUMAN,tr|F5GWT4|F5GWT4_HUMAN,tr|H0Y7J9|H0Y7J9_HUMAN,tr|A0A6Q8PFM0|A0A6Q8PFM0_HUMAN,tr|H0Y493|H0Y493_HUMAN,tr|F8W9F9|F8W9F9_HUMAN,tr|H0Y7R3|H0Y7R3_HUMAN,tr|H0Y7T5|H0Y7T5_HUMAN" 9 1160.5826 1.44 127988 6961 3 1160.581684 387.8681 Serine\threonine-protein kinase WNK1 OS=Homo sapiens OX=9606 GN=WNK1 PE=1 SV=2 6.75 1724.4 - 633685 - - - -0.7789 - 2.372 0.423 - 251.7 1 2 0 -0.0009 10 0 0 0 1.83E+08 1.27E+08 - - - 5.7783 0.9987 221125_WJC_METTL3_EV_vs_WT_F09.06970.06970.3 0.0022 Dec-36 R.K[136.11]GTFTDDLHK[136.11].L "sp|Q9H4A3|WNK1_HUMAN,sp|Q9Y3S1|WNK2_HUMAN,tr|F5GWT4|F5GWT4_HUMAN,tr|H0Y7J9|H0Y7J9_HUMAN,tr|A0A6Q8PFM0|A0A6Q8PFM0_HUMAN,tr|H0Y493|H0Y493_HUMAN,tr|F8W9F9|F8W9F9_HUMAN,tr|H0Y7R3|H0Y7R3_HUMAN,tr|H0Y7T5|H0Y7T5_HUMAN" 9 1176.611 1.44 127995 6970 3 1176.614935 393.2109 Serine\threonine-protein kinase WNK1 OS=Homo sapiens OX=9606 GN=WNK1 PE=1 SV=2 6.75 1725.3 - 1.13E+06 - - - 3.3545 - 2.053 0.329 - 222.2 1 2 0 0.0039 10 0 0 0 1.83E+08 1.27E+08 - - - 4.3076 1 221125_WJC_METTL3_EV_vs_WT_F09.06972.06972.2 1.02E-05 14/32 K.AQGPQQQPGSEGPSYAK[136.11].K "sp|Q3ZCQ8|TIM50_HUMAN,tr|M0R1Y4|M0R1Y4_HUMAN,tr|M0QXC3|M0QXC3_HUMAN,tr|M0R047|M0R047_HUMAN,tr|M0R303|M0R303_HUMAN,tr|M0R2D2|M0R2D2_HUMAN,tr|M0R003|M0R003_HUMAN,tr|M0R2Z3|M0R2Z3_HUMAN" 8 1736.8209 1.23 127997 6972 2 1736.816309 869.4177 Mitochondrial import inner membrane translocase subunit TIM50 OS=Homo sapiens OX=9606 GN=TIMM50 PE=1 SV=2 6.05 1725.5 - 284449 - - - -2.6589 - 2.962 0.551 - 307.3 1 2 0 -0.0046 17 0 0 0 3.90E+07 3.16E+07 - - - 5.7789 1 221125_WJC_METTL3_EV_vs_WT_F09.06976.06976.3 5.75E-05 16/64 K.AQGPQQQPGSEGPSYAK.K "sp|Q3ZCQ8|TIM50_HUMAN,tr|M0R1Y4|M0R1Y4_HUMAN,tr|M0QXC3|M0QXC3_HUMAN,tr|M0R047|M0R047_HUMAN,tr|M0R303|M0R303_HUMAN,tr|M0R2D2|M0R2D2_HUMAN,tr|M0R003|M0R003_HUMAN,tr|M0R2Z3|M0R2Z3_HUMAN" 8 1728.8067 1.36 127999 6976 3 1728.805081 577.2762 Mitochondrial import inner membrane translocase subunit TIM50 OS=Homo sapiens OX=9606 GN=TIMM50 PE=1 SV=2 6.05 1726.1 - 583884 - - - -0.9521 - 2.828 0.552 - 289.7 1 2 0 -0.0016 17 0 0 0 3.33E+07 2.45E+07 - - - 7.3201 0.9642 221125_WJC_METTL3_EV_vs_WT_F09.06986.06986.2 0.0547 20-Jul K.LK[136.11]GDDLQAIK[136.11]K[136.11].E "sp|P07910|HNRPC_HUMAN,tr|B4DY08|B4DY08_HUMAN,tr|G3V5V7|G3V5V7_HUMAN,tr|B2R5W2|B2R5W2_HUMAN,tr|G3V4C1|G3V4C1_HUMAN,tr|G3V576|G3V576_HUMAN,tr|G3V2D6|G3V2D6_HUMAN,tr|G3V4W0|G3V4W0_HUMAN,tr|G3V2Q1|G3V2Q1_HUMAN" 9 1251.7613 1.57 128007 6986 2 1251.763525 626.8879 Heterogeneous nuclear ribonucleoproteins C1\C2 OS=Homo sapiens OX=9606 GN=HNRNPC PE=1 SV=4 8.5 1727.3 - 214579 - - - 1.7879 - 1.336 0.307 - 54.4 2 2 1 0.0022 11 0 0 0 3.23E+07 2.06E+07 - - - 1.957 0.9972 221125_WJC_METTL3_EV_vs_WT_F09.06991.06991.2 0.107 18-Aug R.K[136.11]GTFTDDLHK[136.11].L "sp|Q9H4A3|WNK1_HUMAN,sp|Q9Y3S1|WNK2_HUMAN,tr|F5GWT4|F5GWT4_HUMAN,tr|H0Y7J9|H0Y7J9_HUMAN,tr|A0A6Q8PFM0|A0A6Q8PFM0_HUMAN,tr|H0Y493|H0Y493_HUMAN,tr|F8W9F9|F8W9F9_HUMAN,tr|H0Y7R3|H0Y7R3_HUMAN,tr|H0Y7T5|H0Y7T5_HUMAN" 9 1176.611 1.57 128010 6991 2 1176.609384 589.3128 Serine\threonine-protein kinase WNK1 OS=Homo sapiens OX=9606 GN=WNK1 PE=1 SV=2 6.75 1727.9 - 218513 - - - -1.3632 - 1.528 0.214 - 194.8 1 2 0 -0.0016 10 0 0 0 1.13E+07 7.16E+06 - - - 1.8045 0.9988 221125_WJC_METTL3_EV_vs_WT_F09.06994.06994.2 3.89E-05 13/20 K.LKGDDLQAIKK.E "sp|P07910|HNRPC_HUMAN,tr|B4DY08|B4DY08_HUMAN,tr|G3V5V7|G3V5V7_HUMAN,tr|B2R5W2|B2R5W2_HUMAN,tr|G3V4C1|G3V4C1_HUMAN,tr|G3V576|G3V576_HUMAN,tr|G3V2D6|G3V2D6_HUMAN,tr|G3V4W0|G3V4W0_HUMAN,tr|G3V2Q1|G3V2Q1_HUMAN" 9 1227.7187 1.57 128013 6994 2 1227.717812 614.8666 Heterogeneous nuclear ribonucleoproteins C1\C2 OS=Homo sapiens OX=9606 GN=HNRNPC PE=1 SV=4 8.5 1728.3 - 339659 - - - -0.7127 - 2.564 0.5 - 272.5 1 2 1 -0.0009 11 0 0 0 3.23E+07 2.06E+07 - - - 5.2809 1 221125_WJC_METTL3_EV_vs_WT_F09.06999.06999.3 9.05E-09 15/52 K.K[136.11]GPGEVAGTVTGQK[136.11].R "sp|Q86U44|MTA70_HUMAN,tr|F5H6D8|F5H6D8_HUMAN,tr|H0YFV6|H0YFV6_HUMAN,tr|B4DTN4|B4DTN4_HUMAN" 4 1343.738 0 128015 6999 3 1343.737607 448.9199 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 8.59 1728.9 - 3.63E+06 - - - -0.2768 - 3.013 0.558 - 423.3 1 2 0 -0.0004 14 0 0 0 4.86E+05 2.92E+08 - - - 7.6921 0.9861 221125_WJC_METTL3_EV_vs_WT_F09.07000.07000.3 3.73E-06 Nov-56 R.SDSPVPTAPTSGGPK[136.11].P "sp|Q86U44|MTA70_HUMAN,tr|B4E349|B4E349_HUMAN,tr|F5H6D8|F5H6D8_HUMAN,tr|B4DTN4|B4DTN4_HUMAN" 4 1404.6976 0.001 128016 7000 3 1404.694243 469.2398 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 5.55 1729 - 215791 - - - -2.4069 - 2.225 0.463 - 166.7 1 1 0 -0.0034 15 0 0 0 0.00E+00 1.52E+07 - - - 5.7879 1 221125_WJC_METTL3_EV_vs_WT_F09.07008.07008.2 2.55E-07 20/26 K.K[136.11]GPGEVAGTVTGQK[136.11].R "sp|Q86U44|MTA70_HUMAN,tr|F5H6D8|F5H6D8_HUMAN,tr|H0YFV6|H0YFV6_HUMAN,tr|B4DTN4|B4DTN4_HUMAN" 4 1343.738 0.001 128021 7008 2 1343.737371 672.8763 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 8.59 1730 - 1.08E+06 - - - -0.4525 - 3.527 0.588 - 1042.2 1 2 0 -0.0006 14 0 0 0 0.00E+00 7.10E+07 - - - 6.5468 0.9792 221125_WJC_METTL3_EV_vs_WT_F09.07010.07010.3 5.17E-05 Sep-36 L.K[136.11]GDDLQAIK[136.11]K[136.11].E "sp|P07910|HNRPC_HUMAN,tr|B4DY08|B4DY08_HUMAN,tr|G3V5V7|G3V5V7_HUMAN,tr|B2R5W2|B2R5W2_HUMAN,tr|G3V4C1|G3V4C1_HUMAN,tr|G3V576|G3V576_HUMAN,tr|G3V2D6|G3V2D6_HUMAN,tr|G3V4W0|G3V4W0_HUMAN,tr|G3V2Q1|G3V2Q1_HUMAN" 9 1138.6772 0.001 128022 7010 3 1138.677522 380.5664 Heterogeneous nuclear ribonucleoproteins C1\C2 OS=Homo sapiens OX=9606 GN=HNRNPC PE=1 SV=4 8.5 1730.3 - 388490 - - - 0.2626 - 1.724 0.397 - 123.5 1 1 0 0.0003 10 0 0 0 0.00E+00 1.18E+07 - - - 4.5567 0.9103 221125_WJC_METTL3_EV_vs_WT_F09.07023.07023.2 7.64 24-May K.K[136.11]VEGAGEEQAAKK[136.11].K sp|P07196|NFL_HUMAN 1 1359.7329 - 128028 7023 2 1359.733515 680.8737 Neurofilament light polypeptide OS=Homo sapiens OX=9606 GN=NEFL PE=1 SV=3 6.23 1731.9 - 245769 - - - 0.4567 - 1.093 0.036 - 68.1 5 2 0 0.0006 13 0 0 0 - - - - - -0.7773 0.9993 221125_WJC_METTL3_EV_vs_WT_F09.07034.07034.2 0.00597 20-Jul K.ENAGEDPGLAR.Q sp|P81605|DCD_HUMAN 1 1127.5207 999 128033 7034 2 1127.519693 564.7676 Dermcidin OS=Homo sapiens OX=9606 GN=DCD PE=1 SV=2 4.14 1733.5 - 207404 - - - -0.9073 - 1.337 0.411 - 120.7 1 2 0 -0.001 11 0 0 0 8.74E+06 0.00E+00 - - - 2.862 0.9977 221125_WJC_METTL3_EV_vs_WT_F09.07037.07037.2 8.31E-06 Jun-38 K.EAAGTTAAAGTGGATEQPPR.H "sp|O43290|SNUT1_HUMAN,tr|E9PQI8|E9PQI8_HUMAN" 2 1812.8602 3.95 128034 7037 2 1812.869164 907.4374 U4\U6.U5 tri-snRNP-associated protein 1 OS=Homo sapiens OX=9606 GN=SART1 PE=1 SV=1 4.53 1733.9 - 139451 - - - 4.9342 - 1.905 0.572 - 65.4 1 2 0 0.0089 20 0 0 0 4.77E+06 1.21E+06 - - - 4.8475 0.9996 221125_WJC_METTL3_EV_vs_WT_F09.07039.07039.3 0.000515 Dec-52 R.QSEVPK[136.11]PEDGEPPR[166.11].R "sp|Q9Y520|PRC2C_HUMAN,tr|E7EPN9|E7EPN9_HUMAN" 2 1581.7754 1.18 128035 7039 3 1581.775318 528.2657 Protein PRRC2C OS=Homo sapiens OX=9606 GN=PRRC2C PE=1 SV=4 4.41 1734.1 - 490332 - - - -0.0329 - 1.907 0.328 - 198.1 1 2 0 -0.0001 14 0 0 0 9.84E+07 8.32E+07 - - - 3.9124 0.9999 221125_WJC_METTL3_EV_vs_WT_F09.07052.07052.3 5.61E-05 16/52 R.AQTSGIEEETVKEK.K "sp|P55197|AF10_HUMAN,tr|Q5JT35|Q5JT35_HUMAN,tr|H0Y5P4|H0Y5P4_HUMAN" 3 1547.7679 474.69 128043 7052 3 1547.769242 516.9299 Protein AF-10 OS=Homo sapiens OX=9606 GN=MLLT10 PE=1 SV=2 4.49 1735.9 - 794978 - - - 0.8787 - 3.011 0.534 - 488.4 1 2 1 0.0014 14 0 0 0 2.08E+07 4.37E+04 - - - 7.4225 0.9996 221125_WJC_METTL3_EV_vs_WT_F09.07057.07057.2 3.07E-07 26-Jul K.GPGEVAGTVTGQK[136.11]R[166.11].R "sp|Q86U44|MTA70_HUMAN,tr|F5H6D8|F5H6D8_HUMAN,tr|H0YFV6|H0YFV6_HUMAN,tr|B4DTN4|B4DTN4_HUMAN" 4 1373.7382 0.001 128046 7057 2 1373.741971 687.8764 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 8.75 1736.5 - 105922 - - - 2.7472 - 2.064 0.575 - 122.9 1 2 0 0.0038 14 0 0 0 0.00E+00 6.69E+06 - - - 5.1052 0.9988 221125_WJC_METTL3_EV_vs_WT_F09.07061.07061.3 0.00145 Dec-48 K.IQDK[136.11]EGIPPDQQR[166.11].L "sp|P62979|RS27A_HUMAN,sp|P0CG48|UBC_HUMAN,sp|P0CG48|UBC_HUMAN,sp|P0CG48|UBC_HUMAN,sp|P0CG48|UBC_HUMAN,sp|P0CG48|UBC_HUMAN,sp|P0CG48|UBC_HUMAN,sp|P0CG48|UBC_HUMAN,sp|P0CG48|UBC_HUMAN,sp|P0CG48|UBC_HUMAN,sp|P0CG47|UBB_HUMAN,sp|P0CG47|UBB_HUMAN,sp|P0CG47|UBB_HUMAN,sp|P62987|RL40_HUMAN,tr|F5H388|F5H388_HUMAN,tr|F5H388|F5H388_HUMAN,tr|F5GYU3|F5GYU3_HUMAN,tr|F5GYU3|F5GYU3_HUMAN,tr|B4DV12|B4DV12_HUMAN,tr|B4DV12|B4DV12_HUMAN,tr|J3QSA3|J3QSA3_HUMAN,tr|Q5PY61|Q5PY61_HUMAN,tr|Q5PY61|Q5PY61_HUMAN,tr|Q5PY61|Q5PY61_HUMAN,tr|F5H2Z3|F5H2Z3_HUMAN,tr|F5H2Z3|F5H2Z3_HUMAN,tr|M0R2S1|M0R2S1_HUMAN,tr|J3QS39|J3QS39_HUMAN,tr|J3QTR3|J3QTR3_HUMAN,tr|Q96C32|Q96C32_HUMAN,tr|Q96C32|Q96C32_HUMAN,tr|Q96C32|Q96C32_HUMAN,tr|Q96C32|Q96C32_HUMAN,tr|M0R1V7|M0R1V7_HUMAN,tr|F5H747|F5H747_HUMAN,tr|F5H747|F5H747_HUMAN,tr|F5GXK7|F5GXK7_HUMAN,tr|F5GXK7|F5GXK7_HUMAN,tr|M0R1M6|M0R1M6_HUMAN,tr|F5H6Q2|F5H6Q2_HUMAN,tr|F5H6Q2|F5H6Q2_HUMAN,tr|F5GZ39|F5GZ39_HUMAN,tr|J3QKN0|J3QKN0_HUMAN,tr|J3QKN0|J3QKN0_HUMAN,tr|F5H265|F5H265_HUMAN,tr|F5H265|F5H265_HUMAN,tr|A0A2R8Y422|A0A2R8Y422_HUMAN" 47 1540.7964 0.69 128048 7061 3 1540.796007 514.6061 Ubiquitin-40S ribosomal protein S27a OS=Homo sapiens OX=9606 GN=RPS27A PE=1 SV=2 4.56 1737 - 500320 - - - -0.281 - 2.197 0.327 - 220.9 1 2 1 -0.0004 13 0 0 0 2.89E+07 4.20E+07 - - - 4.3196 1 221125_WJC_METTL3_EV_vs_WT_F09.07066.07066.2 1.65E-10 Aug-38 M.TAEDSTAAMSSDSAAGSSAK.V "sp|A0AV96|RBM47_HUMAN,tr|D6RBP6|D6RBP6_HUMAN,tr|D6RFL5|D6RFL5_HUMAN,tr|D6RA49|D6RA49_HUMAN,tr|D6RCT1|D6RCT1_HUMAN,tr|D6RBS9|D6RBS9_HUMAN,tr|D6R9M7|D6R9M7_HUMAN,tr|D6REZ6|D6REZ6_HUMAN,tr|D6R9D6|D6R9D6_HUMAN" 9 1843.7742 1.53 128052 7066 2 1843.777172 922.8944 RNA-binding protein 47 OS=Homo sapiens OX=9606 GN=RBM47 PE=1 SV=2 4.03 1737.6 - 47834.1 - - - 1.6304 - 1.981 0.749 - 127.7 1 2 0 0.003 20 0 0 0 6.18E+06 4.04E+06 - - - 6.2528 0.9997 221125_WJC_METTL3_EV_vs_WT_F09.07077.07077.2 0.000244 30-Aug K.FSPGAPGGSGSQPNQK.L "sp|Q15942|ZYX_HUMAN,tr|H7C3D3|H7C3D3_HUMAN,tr|H0Y2Y8|H0Y2Y8_HUMAN" 3 1514.7114 3.67 128057 7077 2 1514.712201 758.363 Zyxin OS=Homo sapiens OX=9606 GN=ZYX PE=1 SV=1 8.75 1738.9 - 226392 - - - 0.5486 - 1.654 0.441 - 112.8 1 2 0 0.0008 16 0 0 0 6.52E+07 1.78E+07 - - - 3.5351 0.9779 221125_WJC_METTL3_EV_vs_WT_F09.07080.07080.3 0.0398 Sep-48 K.IQDKEGIPPDQQR.L "sp|P62979|RS27A_HUMAN,sp|P0CG48|UBC_HUMAN,sp|P0CG48|UBC_HUMAN,sp|P0CG48|UBC_HUMAN,sp|P0CG48|UBC_HUMAN,sp|P0CG48|UBC_HUMAN,sp|P0CG48|UBC_HUMAN,sp|P0CG48|UBC_HUMAN,sp|P0CG48|UBC_HUMAN,sp|P0CG48|UBC_HUMAN,sp|P0CG47|UBB_HUMAN,sp|P0CG47|UBB_HUMAN,sp|P0CG47|UBB_HUMAN,sp|P62987|RL40_HUMAN,tr|F5H388|F5H388_HUMAN,tr|F5H388|F5H388_HUMAN,tr|F5GYU3|F5GYU3_HUMAN,tr|F5GYU3|F5GYU3_HUMAN,tr|B4DV12|B4DV12_HUMAN,tr|B4DV12|B4DV12_HUMAN,tr|J3QSA3|J3QSA3_HUMAN,tr|Q5PY61|Q5PY61_HUMAN,tr|Q5PY61|Q5PY61_HUMAN,tr|Q5PY61|Q5PY61_HUMAN,tr|F5H2Z3|F5H2Z3_HUMAN,tr|F5H2Z3|F5H2Z3_HUMAN,tr|M0R2S1|M0R2S1_HUMAN,tr|J3QS39|J3QS39_HUMAN,tr|J3QTR3|J3QTR3_HUMAN,tr|Q96C32|Q96C32_HUMAN,tr|Q96C32|Q96C32_HUMAN,tr|Q96C32|Q96C32_HUMAN,tr|Q96C32|Q96C32_HUMAN,tr|M0R1V7|M0R1V7_HUMAN,tr|F5H747|F5H747_HUMAN,tr|F5H747|F5H747_HUMAN,tr|F5GXK7|F5GXK7_HUMAN,tr|F5GXK7|F5GXK7_HUMAN,tr|M0R1M6|M0R1M6_HUMAN,tr|F5H6Q2|F5H6Q2_HUMAN,tr|F5H6Q2|F5H6Q2_HUMAN,tr|F5GZ39|F5GZ39_HUMAN,tr|J3QKN0|J3QKN0_HUMAN,tr|J3QKN0|J3QKN0_HUMAN,tr|F5H265|F5H265_HUMAN,tr|F5H265|F5H265_HUMAN,tr|A0A2R8Y422|A0A2R8Y422_HUMAN" 47 1522.774 0.69 128059 7080 3 1522.778679 508.5986 Ubiquitin-40S ribosomal protein S27a OS=Homo sapiens OX=9606 GN=RPS27A PE=1 SV=2 4.56 1739.3 - 309281 - - - 3.0924 - 1.873 0.264 - 131.2 1 2 1 0.0047 13 0 0 0 1.53E+07 2.22E+07 - - - 3.1835 0.9824 221125_WJC_METTL3_EV_vs_WT_F09.07083.07083.3 4.05E-06 Nov-60 A.ASYAAQQHPQAAASYR.G sp|Q96PK6|RBM14_HUMAN 1 1718.8125 0.18 128062 7083 3 1718.81931 573.9448 RNA-binding protein 14 OS=Homo sapiens OX=9606 GN=RBM14 PE=1 SV=2 8.64 1739.7 - 163778 - - - 3.9731 - 2.157 0.577 - 105.8 1 1 0 0.0068 16 0 0 0 4.39E+06 2.48E+07 - - - 6.9435 0.9999 221125_WJC_METTL3_EV_vs_WT_F09.07097.07097.3 0.000834 Dec-56 R.SGTTPK[136.11]PVINSTPGR[166.11].T sp|Q99459|CDC5L_HUMAN 1 1528.8328 1.33 128067 7097 3 1528.833835 510.6182 Cell division cycle 5-like protein OS=Homo sapiens OX=9606 GN=CDC5L PE=1 SV=2 11 1741.7 - 378827 - - - 0.66 - 2.396 0.368 - 185.9 1 2 0 0.001 15 0 0 0 2.50E+08 1.88E+08 - - - 4.9226 0.9991 221125_WJC_METTL3_EV_vs_WT_F09.07098.07098.2 0.000736 30-Sep K.FSPGAPGGSGSQPNQK[136.11].L "sp|Q15942|ZYX_HUMAN,tr|H7C3D3|H7C3D3_HUMAN,tr|H0Y2Y8|H0Y2Y8_HUMAN" 3 1522.7256 3.67 128068 7098 2 1522.723479 762.3701 Zyxin OS=Homo sapiens OX=9606 GN=ZYX PE=1 SV=1 8.75 1741.9 - 245510 - - - -1.3732 - 1.387 0.404 - 146.1 1 2 0 -0.0021 16 0 0 0 6.52E+07 1.78E+07 - - - 2.8286 0.9896 221125_WJC_METTL3_EV_vs_WT_F09.07104.07104.2 0.000261 28-Sep F.SAQTAPTTDSLNSSK.S "sp|P55197|AF10_HUMAN,tr|Q5JT35|Q5JT35_HUMAN" 2 1506.7162 999 128072 7104 2 1506.717239 754.3654 Protein AF-10 OS=Homo sapiens OX=9606 GN=MLLT10 PE=1 SV=2 5.55 1742.7 - 81728.9 - - - 0.7022 - 1.901 0.524 - 180.1 1 1 0 0.0011 15 0 0 0 2.95E+06 0.00E+00 - - - 4.4903 0.9997 221125_WJC_METTL3_EV_vs_WT_F09.07107.07107.3 0.00374 13/40 K.EKDVQFEHGYR.L "sp|Q92544|TM9S4_HUMAN,tr|A0A0C4DFM1|A0A0C4DFM1_HUMAN" 2 1406.6579 1.03 128073 7107 3 1406.656982 469.8932 Transmembrane 9 superfamily member 4 OS=Homo sapiens OX=9606 GN=TM9SF4 PE=1 SV=2 5.45 1743.1 - 776531 - - - -0.637 - 2.362 0.405 - 242.6 1 2 1 -0.0009 11 0 0 0 3.27E+07 3.19E+07 - - - 5.4968 0.9999 221125_WJC_METTL3_EV_vs_WT_F09.07108.07108.3 0.000529 Dec-56 R.SGTTPKPVINSTPGR.T sp|Q99459|CDC5L_HUMAN 1 1510.8104 1.33 128074 7108 3 1510.809636 504.6107 Cell division cycle 5-like protein OS=Homo sapiens OX=9606 GN=CDC5L PE=1 SV=2 11 1743.2 - 748208 - - - -0.4766 - 2.243 0.426 - 178.8 1 2 0 -0.0007 15 0 0 0 2.50E+08 1.88E+08 - - - 5.3972 0.9984 221125_WJC_METTL3_EV_vs_WT_F09.07112.07112.4 0.000336 Dec-78 K.AVVVC[160.03]PK[136.11]DEDYK[136.11]QR[166.11].T "sp|Q00839|HNRPU_HUMAN,tr|A0A1W2PQL0|A0A1W2PQL0_HUMAN,tr|A0A1W2PPL4|A0A1W2PPL4_HUMAN,tr|A0A1W2PQ74|A0A1W2PQ74_HUMAN,tr|Q5RI18|Q5RI18_HUMAN,tr|A0A1W2PP35|A0A1W2PP35_HUMAN,tr|A0A1W2PPS1|A0A1W2PPS1_HUMAN,tr|A0A1W2PRZ7|A0A1W2PRZ7_HUMAN,tr|A0A1W2PPH7|A0A1W2PPH7_HUMAN,tr|A0A1W2PQD4|A0A1W2PQD4_HUMAN,tr|A0A1W2PP34|A0A1W2PP34_HUMAN,tr|A0A1X7SBS1|A0A1X7SBS1_HUMAN" 12 1731.8824 0.88 128076 7112 4 1731.886611 433.9779 Heterogeneous nuclear ribonucleoprotein U OS=Homo sapiens OX=9606 GN=HNRNPU PE=1 SV=6 6.16 1743.7 - 165652 - - - 2.417 - 2.113 0.383 - 144.2 1 2 2 0.0042 14 0 0 0 1.00E+07 1.13E+07 - - - 2.8307 0.9999 221125_WJC_METTL3_EV_vs_WT_F09.07116.07116.2 5.25E-07 Jul-38 M.TAEDSTAAMSSDSAAGSSAK[136.11].V "sp|A0AV96|RBM47_HUMAN,tr|D6RBP6|D6RBP6_HUMAN,tr|D6RFL5|D6RFL5_HUMAN,tr|D6RA49|D6RA49_HUMAN,tr|D6RCT1|D6RCT1_HUMAN,tr|D6RBS9|D6RBS9_HUMAN,tr|D6R9M7|D6R9M7_HUMAN,tr|D6REZ6|D6REZ6_HUMAN,tr|D6R9D6|D6R9D6_HUMAN" 9 1851.7884 1.53 128079 7116 2 1851.786038 926.9015 RNA-binding protein 47 OS=Homo sapiens OX=9606 GN=RBM47 PE=1 SV=2 4.03 1744.2 - 135111 - - - -1.2572 - 1.782 0.691 - 112.6 1 2 0 -0.0023 20 0 0 0 6.18E+06 4.04E+06 - - - 5.5644 1 221125_WJC_METTL3_EV_vs_WT_F09.07120.07120.3 2.65E-08 18/68 R.NSVAGSNPAKPGLGSPGR.Y sp|Q86XL3|ANKL2_HUMAN 1 1664.8594 1.99 128080 7120 3 1664.859963 555.9604 Ankyrin repeat and LEM domain-containing protein 2 OS=Homo sapiens OX=9606 GN=ANKLE2 PE=1 SV=4 11 1744.8 - 599810 - - - 0.3195 - 3.09 0.582 - 274.1 1 2 0 0.0005 18 0 0 0 4.30E+07 2.16E+07 - - - 7.8378 1 221125_WJC_METTL3_EV_vs_WT_F09.07122.07122.3 1.08E-07 17/68 R.NSVAGSNPAK[136.11]PGLGSPGR[166.11].Y sp|Q86XL3|ANKL2_HUMAN 1 1682.8819 1.99 128082 7122 3 1682.881385 561.9679 Ankyrin repeat and LEM domain-containing protein 2 OS=Homo sapiens OX=9606 GN=ANKLE2 PE=1 SV=4 11 1745 - 336366 - - - -0.3066 - 2.655 0.55 - 236.6 1 2 0 -0.0005 18 0 0 0 4.30E+07 2.16E+07 - - - 7.1033 1 221125_WJC_METTL3_EV_vs_WT_F09.07132.07132.3 9.48E-05 13/56 K.DQEPK[136.11]PSPEPAAVSR[166.11].G sp|Q9H7S9|ZN703_HUMAN 1 1624.8176 1.75 128088 7132 3 1624.817698 542.6131 Zinc finger protein 703 OS=Homo sapiens OX=9606 GN=ZNF703 PE=1 SV=1 4.68 1746.4 - 670366 - - - 0.0788 - 2.47 0.512 - 182.9 1 2 0 0.0001 15 0 0 0 1.21E+09 6.91E+08 - - - 6.6077 1 221125_WJC_METTL3_EV_vs_WT_F09.07138.07138.3 9.81E-08 20/52 K.GPGEVAGTVTGQK[136.11]R[166.11].R "sp|Q86U44|MTA70_HUMAN,tr|F5H6D8|F5H6D8_HUMAN,tr|H0YFV6|H0YFV6_HUMAN,tr|B4DTN4|B4DTN4_HUMAN" 4 1373.7382 0.17 128092 7138 3 1373.740884 458.92 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 8.75 1747.1 - 780255 - - - 1.956 - 3.271 0.62 - 705 1 2 0 0.0027 14 0 0 0 1.10E+07 6.48E+07 - - - 8.6011 0.9993 221125_WJC_METTL3_EV_vs_WT_F09.07139.07139.3 3.30E-05 13/52 K.AVVVC[160.03]PK[136.11]DEDYK[136.11]QR[166.11].T "sp|Q00839|HNRPU_HUMAN,tr|A0A1W2PQL0|A0A1W2PQL0_HUMAN,tr|A0A1W2PPL4|A0A1W2PPL4_HUMAN,tr|A0A1W2PQ74|A0A1W2PQ74_HUMAN,tr|Q5RI18|Q5RI18_HUMAN,tr|A0A1W2PP35|A0A1W2PP35_HUMAN,tr|A0A1W2PPS1|A0A1W2PPS1_HUMAN,tr|A0A1W2PRZ7|A0A1W2PRZ7_HUMAN,tr|A0A1W2PPH7|A0A1W2PPH7_HUMAN,tr|A0A1W2PQD4|A0A1W2PQD4_HUMAN,tr|A0A1W2PP34|A0A1W2PP34_HUMAN,tr|A0A1X7SBS1|A0A1X7SBS1_HUMAN" 12 1731.8824 1.11 128093 7139 3 1731.888523 578.3014 Heterogeneous nuclear ribonucleoprotein U OS=Homo sapiens OX=9606 GN=HNRNPU PE=1 SV=6 6.16 1747.2 - 163793 - - - 3.521 - 2.409 0.515 - 228 1 2 2 0.0061 14 0 0 0 5.35E+06 4.84E+06 - - - 6.6166 1 221125_WJC_METTL3_EV_vs_WT_F09.07142.07142.3 1.16E-09 19/52 R.NVIHASDSVEGAQR.E "sp|O00746|NDKM_HUMAN,tr|Q4TT34|Q4TT34_HUMAN,tr|A0A087WVT9|A0A087WVT9_HUMAN,tr|F2Z2X0|F2Z2X0_HUMAN" 4 1481.7223 2.13 128094 7142 3 1481.723116 494.9147 "Nucleoside diphosphate kinase, mitochondrial OS=Homo sapiens OX=9606 GN=NME4 PE=1 SV=1" 5.32 1747.6 - 1.67E+06 - - - 0.5716 - 3.522 0.636 - 438.4 1 2 0 0.0008 14 0 0 0 2.36E+08 1.11E+08 - - - 8.9764 1 221125_WJC_METTL3_EV_vs_WT_F09.07143.07143.2 2.70E-09 26-Dec R.NVIHASDSVEGAQR.E "sp|O00746|NDKM_HUMAN,tr|Q4TT34|Q4TT34_HUMAN,tr|A0A087WVT9|A0A087WVT9_HUMAN,tr|F2Z2X0|F2Z2X0_HUMAN" 4 1481.7223 2.1 128095 7143 2 1481.725687 741.8684 "Nucleoside diphosphate kinase, mitochondrial OS=Homo sapiens OX=9606 GN=NME4 PE=1 SV=1" 5.32 1747.8 - 180946 - - - 2.3068 - 2.456 0.687 - 504.8 1 2 0 0.0034 14 0 0 0 2.86E+07 1.36E+07 - - - 6.3689 1 221125_WJC_METTL3_EV_vs_WT_F09.07147.07147.3 2.80E-08 15/52 R.NVIHASDSVEGAQR[166.11].E "sp|O00746|NDKM_HUMAN,tr|Q4TT34|Q4TT34_HUMAN,tr|A0A087WVT9|A0A087WVT9_HUMAN,tr|F2Z2X0|F2Z2X0_HUMAN" 4 1491.7305 2.14 128097 7147 3 1491.732516 498.2508 "Nucleoside diphosphate kinase, mitochondrial OS=Homo sapiens OX=9606 GN=NME4 PE=1 SV=1" 5.32 1748.3 - 1.55E+06 - - - 1.3253 - 3.004 0.574 - 328.8 1 2 0 0.002 14 0 0 0 2.36E+08 1.10E+08 - - - 7.8621 1 221125_WJC_METTL3_EV_vs_WT_F09.07149.07149.3 0.000259 14/64 K.VEDAADSATK[136.11]PENLSSK[136.11].T sp|P46013|KI67_HUMAN 1 1776.8712 1.24 128099 7149 3 1776.872196 593.2977 Proliferation marker protein Ki-67 OS=Homo sapiens OX=9606 GN=MKI67 PE=1 SV=2 4.32 1748.5 - 241944 - - - 0.5391 - 2.854 0.514 - 146.5 1 2 0 0.001 17 0 0 0 9.43E+06 7.59E+06 - - - 6.9197 1 221125_WJC_METTL3_EV_vs_WT_F09.07152.07152.3 9.82E-07 Dec-64 K.VEDAADSATKPENLSSK.T sp|P46013|KI67_HUMAN 1 1760.8428 1.24 128100 7152 3 1760.843183 587.9549 Proliferation marker protein Ki-67 OS=Homo sapiens OX=9606 GN=MKI67 PE=1 SV=2 4.32 1748.9 - 290513 - - - 0.1959 - 2.509 0.461 - 126.9 1 2 0 0.0003 17 0 0 0 9.43E+06 7.59E+06 - - - 6.0035 0.9999 221125_WJC_METTL3_EV_vs_WT_F09.07153.07153.2 1.50E-05 26-Nov R.NVIHASDSVEGAQR[166.11].E "sp|O00746|NDKM_HUMAN,tr|Q4TT34|Q4TT34_HUMAN,tr|A0A087WVT9|A0A087WVT9_HUMAN,tr|F2Z2X0|F2Z2X0_HUMAN" 4 1491.7305 2.1 128101 7153 2 1491.732496 746.8725 "Nucleoside diphosphate kinase, mitochondrial OS=Homo sapiens OX=9606 GN=NME4 PE=1 SV=1" 5.32 1749.1 - 266736 - - - 1.3119 - 2.483 0.538 - 419.5 1 2 0 0.002 14 0 0 0 2.86E+07 1.36E+07 - - - 5.2963 0.985 221125_WJC_METTL3_EV_vs_WT_F09.07159.07159.3 0.819 Sep-44 K.TIIQNPTDQQK[136.11]K[136.11].D "sp|Q9UQ80|PA2G4_HUMAN,tr|F8VR77|F8VR77_HUMAN" 2 1428.7907 0.24 128105 7159 3 1428.79144 477.2709 Proliferation-associated protein 2G4 OS=Homo sapiens OX=9606 GN=PA2G4 PE=1 SV=3 8.26 1749.9 - 1.03E+06 - - - 0.4878 - 1.321 0.202 - 62.2 1 2 0 0.0007 12 0 0 0 1.30E+07 5.53E+07 - - - 1.5636 0.9987 221125_WJC_METTL3_EV_vs_WT_F09.07160.07160.2 0.165 28-Jul R.SGTTPK[136.11]PVINSTPGR[166.11].T sp|Q99459|CDC5L_HUMAN 1 1528.8328 1.54 128106 7160 2 1528.830822 765.4237 Cell division cycle 5-like protein OS=Homo sapiens OX=9606 GN=CDC5L PE=1 SV=2 11 1750 - 150241 - - - -1.3108 - 1.221 0.393 - 98.7 1 2 0 -0.002 15 0 0 0 1.07E+07 6.94E+06 - - - 2.434 0.8077 221125_WJC_METTL3_EV_vs_WT_F09.07165.07165.3 0.121 Jun-36 R.DSDKTDTDWR.A "sp|P23588|IF4B_HUMAN,tr|E7EX17|E7EX17_HUMAN,tr|F8VSC7|F8VSC7_HUMAN,tr|F8W0K0|F8W0K0_HUMAN,tr|F8VP89|F8VP89_HUMAN" 5 1237.5211 2.5 128109 7165 3 1237.523125 413.5143 Eukaryotic translation initiation factor 4B OS=Homo sapiens OX=9606 GN=EIF4B PE=1 SV=2 4.14 1750.7 - 382102 - - - 1.6291 - 1.094 0.207 - 42.2 1 2 1 0.002 10 0 0 0 6.17E+07 2.47E+07 - - - 1.1097 0.9975 221125_WJC_METTL3_EV_vs_WT_F09.07170.07170.3 0.0281 Sep-44 R.LKPPVHYNGPSK.A "sp|P55265|DSRAD_HUMAN,tr|A0A3B3ITG9|A0A3B3ITG9_HUMAN,tr|A0A3B3IRQ9|A0A3B3IRQ9_HUMAN,tr|A0A3B3ISU1|A0A3B3ISU1_HUMAN,tr|A0A7P0Z4K3|A0A7P0Z4K3_HUMAN,tr|A0A7P0TA14|A0A7P0TA14_HUMAN,tr|A0A3B3ISX1|A0A3B3ISX1_HUMAN,tr|A0A7P0Z4F9|A0A7P0Z4F9_HUMAN" 8 1335.7299 0.82 128114 7170 3 1335.729754 446.2506 Double-stranded RNA-specific adenosine deaminase OS=Homo sapiens OX=9606 GN=ADAR PE=1 SV=4 9.7 1751.3 - 358815 - - - -0.1243 - 1.446 0.279 - 60.4 1 2 0 -0.0002 12 0 0 0 1.92E+07 2.34E+07 - - - 2.6728 0.9999 221125_WJC_METTL3_EV_vs_WT_F09.07174.07174.3 8.62E-06 15/52 R.QSEVPKPEDGEPPR.R "sp|Q9Y520|PRC2C_HUMAN,tr|E7EPN9|E7EPN9_HUMAN" 2 1563.7529 1.19 128116 7174 3 1563.756636 522.2582 Protein PRRC2C OS=Homo sapiens OX=9606 GN=PRRC2C PE=1 SV=4 4.41 1751.9 - 2.00E+06 - - - 2.3891 - 2.445 0.529 - 317.5 1 2 0 0.0037 14 0 0 0 9.81E+07 8.21E+07 - - - 6.8127 0.9908 221125_WJC_METTL3_EV_vs_WT_F09.07175.07175.3 0.281 Jul-36 R.K[136.11]IVDQIR[166.11]PDR[166.11].Q "sp|Q92841|DDX17_HUMAN,sp|P17844|DDX5_HUMAN,tr|A0A7I2V5F5|A0A7I2V5F5_HUMAN,tr|J3KRZ1|J3KRZ1_HUMAN,tr|J3QSF1|J3QSF1_HUMAN,tr|A0A7I2V507|A0A7I2V507_HUMAN,tr|A0A5H1ZRQ2|A0A5H1ZRQ2_HUMAN,tr|J3KTA4|J3KTA4_HUMAN,tr|A0A0G2JLI4|A0A0G2JLI4_HUMAN,tr|A0A1X7SBZ2|A0A1X7SBZ2_HUMAN,tr|A0A7I2V2S0|A0A7I2V2S0_HUMAN" 11 1266.7403 1.48 128117 7175 3 1266.739808 423.254 Probable ATP-dependent RNA helicase DDX17 OS=Homo sapiens OX=9606 GN=DDX17 PE=1 SV=2 8.75 1752 - 390394 - - - -0.356 - 1.445 0.201 - 69.8 1 2 0 -0.0005 10 0 0 0 4.91E+08 3.32E+08 - - - 1.8559 0.9641 221125_WJC_METTL3_EV_vs_WT_F09.07176.07176.3 0.0196 Jun-36 R.DSDK[136.11]TDTDWR[166.11].A "sp|P23588|IF4B_HUMAN,tr|E7EX17|E7EX17_HUMAN,tr|F8VSC7|F8VSC7_HUMAN,tr|F8W0K0|F8W0K0_HUMAN,tr|F8VP89|F8VP89_HUMAN" 5 1255.5436 2.5 128118 7176 3 1255.545127 419.5218 Eukaryotic translation initiation factor 4B OS=Homo sapiens OX=9606 GN=EIF4B PE=1 SV=2 4.14 1752.1 - 468731 - - - 1.2329 - 1.442 0.221 - 55.3 1 2 1 0.0015 10 0 0 0 6.19E+07 2.47E+07 - - - 2.0725 0.9974 221125_WJC_METTL3_EV_vs_WT_F09.07177.07177.3 0.0168 Sep-56 K.QASRPPIQNAC[160.03]VADK.H sp|Q96EU6|RRP36_HUMAN 1 1653.8257 1.56 128119 7177 3 1653.828654 552.2825 Ribosomal RNA processing protein 36 homolog OS=Homo sapiens OX=9606 GN=RRP36 PE=1 SV=1 8.22 1752.2 - 199736 - - - 1.7934 - 1.517 0.303 - 85.3 1 2 0 0.003 15 0 0 0 2.11E+07 1.35E+07 - - - 3.0047 0.9998 221125_WJC_METTL3_EV_vs_WT_F09.07187.07187.3 3.83E-05 Dec-52 R.TSC[160.03]KDDEAVVQAPR.H "sp|P35658|NU214_HUMAN,tr|A0A0A0MSW3|A0A0A0MSW3_HUMAN,tr|A0A494C1F2|A0A494C1F2_HUMAN" 3 1574.7359 2.06 128125 7187 3 1574.734615 525.9192 Nuclear pore complex protein Nup214 OS=Homo sapiens OX=9606 GN=NUP214 PE=1 SV=2 4.56 1753.6 - 367236 - - - -0.797 - 2.235 0.503 - 180.1 1 2 1 -0.0013 14 0 0 0 3.30E+08 1.60E+08 - - - 6.2849 0.997 221125_WJC_METTL3_EV_vs_WT_F09.07188.07188.2 0.00381 18-Sep R.DSDKTDTDWR.A "sp|P23588|IF4B_HUMAN,tr|E7EX17|E7EX17_HUMAN,tr|F8VSC7|F8VSC7_HUMAN,tr|F8W0K0|F8W0K0_HUMAN,tr|F8VP89|F8VP89_HUMAN" 5 1237.5211 3.31 128126 7188 2 1237.52255 619.7678 Eukaryotic translation initiation factor 4B OS=Homo sapiens OX=9606 GN=EIF4B PE=1 SV=2 4.14 1753.7 - 231268 - - - 1.1644 - 1.576 0.52 - 256.5 1 2 1 0.0014 10 0 0 0 9.19E+06 2.78E+06 - - - 4.151 0.9998 221125_WJC_METTL3_EV_vs_WT_F09.07193.07193.3 0.000593 13/52 R.SPVSTR[166.11]PLPSASQK[136.11].A sp|Q8ND56|LS14A_HUMAN 1 1471.8114 1.33 128129 7193 3 1471.814581 491.6111 Protein LSM14 homolog A OS=Homo sapiens OX=9606 GN=LSM14A PE=1 SV=3 11 1754.4 - 602528 - - - 2.1871 - 2.43 0.405 - 212.7 1 2 0 0.0032 14 0 0 0 7.54E+07 5.66E+07 - - - 5.4141 0.997 221125_WJC_METTL3_EV_vs_WT_F09.07195.07195.3 0.064 Oct-52 R.SPVSTRPLPSASQK.A sp|Q8ND56|LS14A_HUMAN 1 1453.7889 1.36 128131 7195 3 1453.791233 485.6036 Protein LSM14 homolog A OS=Homo sapiens OX=9606 GN=LSM14A PE=1 SV=3 11 1754.6 - 547298 - - - 1.6103 - 2.176 0.201 - 127.4 1 2 0 0.0023 14 0 0 0 7.77E+07 5.72E+07 - - - 2.8465 0.9997 221125_WJC_METTL3_EV_vs_WT_F09.07196.07196.3 5.85E-07 13/52 R.TSC[160.03]K[136.11]DDEAVVQAPR[166.11].H "sp|P35658|NU214_HUMAN,tr|A0A0A0MSW3|A0A0A0MSW3_HUMAN,tr|A0A494C1F2|A0A494C1F2_HUMAN" 3 1592.7583 2.08 128132 7196 3 1592.75963 531.9267 Nuclear pore complex protein Nup214 OS=Homo sapiens OX=9606 GN=NUP214 PE=1 SV=2 4.56 1754.7 - 458901 - - - 0.8099 - 2.481 0.423 - 246.7 1 2 1 0.0013 14 0 0 0 3.29E+08 1.58E+08 - - - 5.6705 0.9995 221125_WJC_METTL3_EV_vs_WT_F09.07197.07197.3 0.0346 Dec-56 K.QASR[166.11]PPIQNAC[160.03]VADK[136.11].H sp|Q96EU6|RRP36_HUMAN 1 1671.8482 1.68 128133 7197 3 1671.847655 558.29 Ribosomal RNA processing protein 36 homolog OS=Homo sapiens OX=9606 GN=RRP36 PE=1 SV=1 8.22 1754.9 - 537120 - - - -0.3009 - 1.8 0.339 - 149.7 1 2 0 -0.0005 15 0 0 0 2.27E+07 1.35E+07 - - - 3.8531 0.9668 221125_WJC_METTL3_EV_vs_WT_F09.07203.07203.4 0.0448 16/84 K.TKEGVVHGVATVAEK.T "sp|P37840|SYUA_HUMAN,tr|A0A669KB41|A0A669KB41_HUMAN,tr|D6RA31|D6RA31_HUMAN,tr|A0A669KBH5|A0A669KBH5_HUMAN,tr|E7EPV7|E7EPV7_HUMAN" 5 1523.8308 1.61 128137 7203 4 1523.835287 381.965 Alpha-synuclein OS=Homo sapiens OX=9606 GN=SNCA PE=1 SV=1 6.42 1755.7 - 440657 - - - 2.9728 - 2.021 0.248 - 145.1 1 2 1 0.0045 15 0 0 0 1.61E+08 1.00E+08 - - - 1.6351 0.9906 221125_WJC_METTL3_EV_vs_WT_F09.07204.07204.3 0.462 Sep-36 R.KIVDQIRPDR.Q "sp|Q92841|DDX17_HUMAN,sp|P17844|DDX5_HUMAN,tr|A0A7I2V5F5|A0A7I2V5F5_HUMAN,tr|J3KRZ1|J3KRZ1_HUMAN,tr|J3QSF1|J3QSF1_HUMAN,tr|A0A7I2V507|A0A7I2V507_HUMAN,tr|A0A5H1ZRQ2|A0A5H1ZRQ2_HUMAN,tr|J3KTA4|J3KTA4_HUMAN,tr|A0A0G2JLI4|A0A0G2JLI4_HUMAN,tr|A0A1X7SBZ2|A0A1X7SBZ2_HUMAN,tr|A0A7I2V2S0|A0A7I2V2S0_HUMAN" 11 1238.7095 1.48 128138 7204 3 1238.71077 413.9104 Probable ATP-dependent RNA helicase DDX17 OS=Homo sapiens OX=9606 GN=DDX17 PE=1 SV=2 8.75 1755.8 - 3.39E+06 - - - 1.0099 - 1.348 0.224 - 178.6 1 2 0 0.0013 10 0 0 0 4.91E+08 3.32E+08 - - - 1.9091 0.9971 221125_WJC_METTL3_EV_vs_WT_F09.07209.07209.3 0.00883 Jun-60 R.ESVSTASDQPSHSLER.Q "sp|Q8TEW0|PARD3_HUMAN,tr|Q5VWV2|Q5VWV2_HUMAN,tr|F5GZI3|F5GZI3_HUMAN,tr|Q5VWU8|Q5VWU8_HUMAN" 4 1728.7915 0.95 128141 7209 3 1728.794071 577.2711 Partitioning defective 3 homolog OS=Homo sapiens OX=9606 GN=PARD3 PE=1 SV=2 4.65 1756.3 - 118200 - - - 1.5039 - 1.417 0.304 - 33 1 2 0 0.0026 16 0 0 0 3.25E+06 3.44E+06 - - - 2.8229 0.9999 221125_WJC_METTL3_EV_vs_WT_F09.07211.07211.3 2.04E-05 16/56 K.TK[136.11]EGVVHGVATVAEK[136.11].T "sp|P37840|SYUA_HUMAN,tr|A0A669KB41|A0A669KB41_HUMAN,tr|D6RA31|D6RA31_HUMAN,tr|A0A669KBH5|A0A669KBH5_HUMAN,tr|E7EPV7|E7EPV7_HUMAN" 5 1539.8592 1.62 128142 7211 3 1539.861699 514.2937 Alpha-synuclein OS=Homo sapiens OX=9606 GN=SNCA PE=1 SV=1 6.42 1756.6 - 3.17E+06 - - - 1.6508 - 2.968 0.537 - 193.4 1 2 1 0.0025 15 0 0 0 7.51E+08 4.64E+08 - - - 7.365 0.9981 221125_WJC_METTL3_EV_vs_WT_F09.07213.07213.4 0.0196 16/84 K.TK[136.11]EGVVHGVATVAEK[136.11].T "sp|P37840|SYUA_HUMAN,tr|A0A669KB41|A0A669KB41_HUMAN,tr|D6RA31|D6RA31_HUMAN,tr|A0A669KBH5|A0A669KBH5_HUMAN,tr|E7EPV7|E7EPV7_HUMAN" 5 1539.8592 1.61 128144 7213 4 1539.862002 385.9721 Alpha-synuclein OS=Homo sapiens OX=9606 GN=SNCA PE=1 SV=1 6.42 1756.8 - 800553 - - - 1.8476 - 2.472 0.345 - 165.5 1 2 1 0.0028 15 0 0 0 1.61E+08 1.00E+08 - - - 2.5519 0.9987 221125_WJC_METTL3_EV_vs_WT_F09.07214.07214.2 2.02E-07 14/28 K.TKEGVVHGVATVAEK.T "sp|P37840|SYUA_HUMAN,tr|A0A669KB41|A0A669KB41_HUMAN,tr|D6RA31|D6RA31_HUMAN,tr|A0A669KBH5|A0A669KBH5_HUMAN,tr|E7EPV7|E7EPV7_HUMAN" 5 1523.8308 1.67 128145 7214 2 1523.832281 762.9227 Alpha-synuclein OS=Homo sapiens OX=9606 GN=SNCA PE=1 SV=1 6.42 1756.9 - 205444 - - - 1.0001 - 2.734 0.556 - 553.1 1 2 1 0.0015 15 0 0 0 4.45E+07 2.66E+07 - - - 5.6199 1 221125_WJC_METTL3_EV_vs_WT_F09.07215.07215.2 4.74E-08 14/28 K.TK[136.11]EGVVHGVATVAEK[136.11].T "sp|P37840|SYUA_HUMAN,tr|A0A669KB41|A0A669KB41_HUMAN,tr|D6RA31|D6RA31_HUMAN,tr|A0A669KBH5|A0A669KBH5_HUMAN,tr|E7EPV7|E7EPV7_HUMAN" 5 1539.8592 1.67 128146 7215 2 1539.861091 770.9369 Alpha-synuclein OS=Homo sapiens OX=9606 GN=SNCA PE=1 SV=1 6.42 1757.1 - 120829 - - - 1.256 - 2.847 0.612 - 476.4 1 2 1 0.0019 15 0 0 0 4.44E+07 2.66E+07 - - - 6.1329 0.9999 221125_WJC_METTL3_EV_vs_WT_F09.07219.07219.3 0.00989 22/56 K.TKEGVVHGVATVAEK.T "sp|P37840|SYUA_HUMAN,tr|A0A669KB41|A0A669KB41_HUMAN,tr|D6RA31|D6RA31_HUMAN,tr|A0A669KBH5|A0A669KBH5_HUMAN,tr|E7EPV7|E7EPV7_HUMAN" 5 1523.8308 1.62 128148 7219 3 1523.833413 508.9509 Alpha-synuclein OS=Homo sapiens OX=9606 GN=SNCA PE=1 SV=1 6.42 1757.5 - 6.78E+06 - - - 1.743 - 4.123 0.509 - 433.6 1 2 1 0.0027 15 0 0 0 7.50E+08 4.64E+08 - - - 7.9105 0.9998 221125_WJC_METTL3_EV_vs_WT_F09.07224.07224.2 2.60E-05 28-Jul R.NSASATTPLSGNSSR[166.11].R "sp|Q9Y608|LRRF2_HUMAN,tr|C9JSU1|C9JSU1_HUMAN" 2 1458.6938 0.91 128153 7224 2 1458.695887 730.3542 Leucine-rich repeat flightless-interacting protein 2 OS=Homo sapiens OX=9606 GN=LRRFIP2 PE=1 SV=1 9.75 1758.1 - 100729 - - - 1.4177 - 1.763 0.586 - 135.6 1 2 0 0.0021 15 0 0 0 1.99E+06 2.19E+06 - - - 4.7626 1 221125_WJC_METTL3_EV_vs_WT_F09.07225.07225.2 1.53E-08 26-Sep R.TSC[160.03]KDDEAVVQAPR.H "sp|P35658|NU214_HUMAN,tr|A0A0A0MSW3|A0A0A0MSW3_HUMAN,tr|A0A494C1F2|A0A494C1F2_HUMAN" 3 1574.7359 2.45 128154 7225 2 1574.73606 788.3752 Nuclear pore complex protein Nup214 OS=Homo sapiens OX=9606 GN=NUP214 PE=1 SV=2 4.56 1758.3 - 74305.8 - - - 0.1207 - 2.159 0.665 - 314.4 1 2 1 0.0002 14 0 0 0 1.01E+07 4.13E+06 - - - 5.884 0.9844 221125_WJC_METTL3_EV_vs_WT_F09.07228.07228.2 3.28 18-Jun R.KIVDQIRPDR.Q "sp|Q92841|DDX17_HUMAN,sp|P17844|DDX5_HUMAN,tr|A0A7I2V5F5|A0A7I2V5F5_HUMAN,tr|J3KRZ1|J3KRZ1_HUMAN,tr|J3QSF1|J3QSF1_HUMAN,tr|A0A7I2V507|A0A7I2V507_HUMAN,tr|A0A5H1ZRQ2|A0A5H1ZRQ2_HUMAN,tr|J3KTA4|J3KTA4_HUMAN,tr|A0A0G2JLI4|A0A0G2JLI4_HUMAN,tr|A0A1X7SBZ2|A0A1X7SBZ2_HUMAN,tr|A0A7I2V2S0|A0A7I2V2S0_HUMAN" 11 1238.7095 1.69 128155 7228 2 1238.710043 620.362 Probable ATP-dependent RNA helicase DDX17 OS=Homo sapiens OX=9606 GN=DDX17 PE=1 SV=2 8.75 1758.7 - 506078 - - - 0.423 - 1.089 0.147 - 83.3 1 2 0 0.0005 10 0 0 0 3.40E+07 2.02E+07 - - - 0.3646 0.9971 221125_WJC_METTL3_EV_vs_WT_F09.07229.07229.2 0.000118 26-Jul R.TSC[160.03]K[136.11]DDEAVVQAPR[166.11].H "sp|P35658|NU214_HUMAN,tr|A0A0A0MSW3|A0A0A0MSW3_HUMAN,tr|A0A494C1F2|A0A494C1F2_HUMAN" 3 1592.7583 2.45 128156 7229 2 1592.759033 797.3864 Nuclear pore complex protein Nup214 OS=Homo sapiens OX=9606 GN=NUP214 PE=1 SV=2 4.56 1758.8 - 72322.6 - - - 0.4351 - 1.584 0.494 - 161.7 1 2 1 0.0007 14 0 0 0 1.01E+07 4.13E+06 - - - 3.8437 0.9436 221125_WJC_METTL3_EV_vs_WT_F09.07235.07235.2 1.37 26-Apr R.SPVSTRPLPSASQK.A sp|Q8ND56|LS14A_HUMAN 1 1453.7889 1.69 128160 7235 2 1453.789972 727.9017 Protein LSM14 homolog A OS=Homo sapiens OX=9606 GN=LSM14A PE=1 SV=3 11 1759.6 - 72218.8 - - - 0.7429 - 0.947 0.111 - 25.9 2 2 0 0.0011 14 0 0 0 1.94E+06 1.15E+06 - - - -0.4106 1 221125_WJC_METTL3_EV_vs_WT_F09.07236.07236.3 0.000143 14/56 K.ATKPQPVNTSSVTVK.S sp|Q8WWK9|CKAP2_HUMAN 1 1555.857 0.89 128161 7236 3 1555.85657 519.6263 Cytoskeleton-associated protein 2 OS=Homo sapiens OX=9606 GN=CKAP2 PE=1 SV=1 10 1759.6 - 887477 - - - -0.2584 - 2.516 0.452 - 222.1 1 2 0 -0.0004 15 0 0 0 1.13E+08 1.27E+08 - - - 5.9868 1 221125_WJC_METTL3_EV_vs_WT_F09.07241.07241.2 0.000313 18/26 K.K[136.11]GPGEVAGTVTGQK[136.11].R "sp|Q86U44|MTA70_HUMAN,tr|F5H6D8|F5H6D8_HUMAN,tr|H0YFV6|H0YFV6_HUMAN,tr|B4DTN4|B4DTN4_HUMAN" 4 1343.738 0.001 128164 7241 2 1343.737562 672.8763 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 8.59 1760.2 - 589943 - - - -0.3103 - 3.388 0.576 - 716 1 2 0 -0.0004 14 0 0 0 0.00E+00 5.40E+07 - - - 6.3573 1 221125_WJC_METTL3_EV_vs_WT_F09.07246.07246.2 3.11E-08 22/38 R.SGGGGGGGGC[160.03]GGGGGVSSLR.L "sp|P13645|K1C10_HUMAN,tr|A0A1B0GVI3|A0A1B0GVI3_HUMAN" 2 1548.6699 999 128167 7246 2 1548.669333 775.3422 "Keratin, type I cytoskeletal 10 OS=Homo sapiens OX=9606 GN=KRT10 PE=1 SV=6" 7.96 1760.9 - 949918 - - - -0.3765 - 4.237 0.717 - 1411.5 1 2 0 -0.0006 20 0 0 0 6.90E+08 0.00E+00 - - - 7.8864 0.9915 221125_WJC_METTL3_EV_vs_WT_F09.07257.07257.2 2.73E-05 13/26 L.ALTQSVGGDSSADR[166.11].L "sp|Q86U44|MTA70_HUMAN,tr|H0YFV6|H0YFV6_HUMAN" 2 1372.6458 0.001 128174 7257 2 1372.644446 687.3302 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 4.21 1762.3 - 331486 - - - -0.9908 - 2.163 0.529 - 540.1 1 1 0 -0.0014 14 0 0 0 0.00E+00 2.49E+07 - - - 4.8838 0.9108 221125_WJC_METTL3_EV_vs_WT_F09.07267.07267.2 0.798 28-Apr K.ATKPQPVNTSSVTVK.S sp|Q8WWK9|CKAP2_HUMAN 1 1555.857 0.63 128179 7267 2 1555.859975 778.9358 Cytoskeleton-associated protein 2 OS=Homo sapiens OX=9606 GN=CKAP2 PE=1 SV=1 10 1763.7 - 101948 - - - 1.9301 - 0.907 0.147 - 25 3 2 0 0.003 15 0 0 0 2.56E+06 4.04E+06 - - - -0.3273 0.9213 221125_WJC_METTL3_EV_vs_WT_F09.07286.07286.3 4.62E-06 9/108 K.GAAAAAAASGAAGGGGGGAGAGAPGGGR[166.11].L sp|Q68E01|INT3_HUMAN 1 1961.9291 1.07 128186 7286 3 1962.925326 654.9837 Integrator complex subunit 3 OS=Homo sapiens OX=9606 GN=INTS3 PE=1 SV=1 9.75 1766.2 - 80878.3 - - - 507.7625 - 1.933 0.364 - 50.4 1 2 0 0.9962 28 0 0 0 2.19E+06 2.06E+06 - - - 3.8386 1 221125_WJC_METTL3_EV_vs_WT_F09.07291.07291.3 0.000619 14/56 K.ATK[136.11]PQPVNTSSVTVK[136.11].S sp|Q8WWK9|CKAP2_HUMAN 1 1571.8854 0.89 128188 7291 3 1571.886859 524.9691 Cytoskeleton-associated protein 2 OS=Homo sapiens OX=9606 GN=CKAP2 PE=1 SV=1 10 1766.8 - 3.50E+06 - - - 0.946 - 2.628 0.475 - 311.3 1 2 0 0.0015 15 0 0 0 1.13E+08 1.27E+08 - - - 6.3566 0.9999 221125_WJC_METTL3_EV_vs_WT_F09.07292.07292.3 1.55E-05 Nov-36 K.HLYQIEKPC[160.03]K.E sp|O00443|P3C2A_HUMAN 1 1314.6754 0.59 128189 7292 3 1314.674957 439.2324 Phosphatidylinositol 4-phosphate 3-kinase C2 domain-containing subunit alpha OS=Homo sapiens OX=9606 GN=PIK3C2A PE=1 SV=2 8.18 1766.9 - 626521 - - - -0.3689 - 2.073 0.427 - 242.2 1 2 0 -0.0005 10 0 0 0 3.88E+07 6.59E+07 - - - 5.4295 0.999 221125_WJC_METTL3_EV_vs_WT_F09.07297.07297.3 0.000178 Sep-64 K.AASSGPGKPSGLQYESK.L "sp|Q9NZM4|BICRA_HUMAN,tr|A0A087WWH3|A0A087WWH3_HUMAN" 2 1662.8213 3.74 128192 7297 3 1662.8272 555.281 BRD4-interacting chromatin-remodeling complex-associated protein OS=Homo sapiens OX=9606 GN=BICRA PE=1 SV=2 8.54 1767.6 - 193436 - - - 3.5398 - 1.913 0.404 - 46.5 1 2 0 0.0059 17 0 0 0 4.75E+06 1.27E+06 - - - 4.6813 0.8632 221125_WJC_METTL3_EV_vs_WT_F09.07298.07298.2 0.0368 Apr-34 R.SGAPPPSGSAVSTAPQPK.P "sp|Q96SB4|SRPK1_HUMAN,tr|H3BLV9|H3BLV9_HUMAN" 2 1634.8264 1.29 128193 7298 2 1634.82455 818.4205 SRSF protein kinase 1 OS=Homo sapiens OX=9606 GN=SRPK1 PE=1 SV=2 8.47 1767.7 - 75452.2 - - - -1.1316 - 0.984 0.374 - 23.9 1 1 0 -0.0019 18 0 0 0 6.84E+06 5.30E+06 - - - 1.7631 0.9998 221125_WJC_METTL3_EV_vs_WT_F09.07303.07303.4 2.51E-05 17/84 K.LTGR[166.11]DPNDVR[166.11]PIQAR[166.11].L "sp|Q9H307|PININ_HUMAN,tr|G3V5F0|G3V5F0_HUMAN,tr|G3V579|G3V579_HUMAN" 3 1736.9424 1.65 128195 7303 4 1736.942118 435.2429 Pinin OS=Homo sapiens OX=9606 GN=PNN PE=1 SV=5 9.51 1768.4 - 680611 - - - -0.1767 - 2.219 0.478 - 156.9 1 2 1 -0.0003 15 0 0 0 1.10E+08 6.64E+07 - - - 3.6716 0.9965 221125_WJC_METTL3_EV_vs_WT_F09.07307.07307.3 0.00478 Nov-56 K.LTGRDPNDVRPIQAR.L "sp|Q9H307|PININ_HUMAN,tr|G3V5F0|G3V5F0_HUMAN,tr|G3V579|G3V579_HUMAN" 3 1706.9176 1.71 128197 7307 3 1706.918445 569.9798 Pinin OS=Homo sapiens OX=9606 GN=PNN PE=1 SV=5 9.51 1769 - 876867 - - - 0.4863 - 1.838 0.302 - 95.6 1 2 1 0.0008 15 0 0 0 5.34E+07 3.12E+07 - - - 3.495 0.9997 221125_WJC_METTL3_EV_vs_WT_F09.07309.07309.3 3.08E-06 14/56 K.LTGR[166.11]DPNDVR[166.11]PIQAR[166.11].L "sp|Q9H307|PININ_HUMAN,tr|G3V5F0|G3V5F0_HUMAN,tr|G3V579|G3V579_HUMAN" 3 1736.9424 1.71 128198 7309 3 1736.944641 579.9881 Pinin OS=Homo sapiens OX=9606 GN=PNN PE=1 SV=5 9.51 1769.2 - 687431 - - - 1.2758 - 2.203 0.475 - 152 1 2 1 0.0022 15 0 0 0 5.34E+07 3.12E+07 - - - 5.8961 0.8987 221125_WJC_METTL3_EV_vs_WT_F09.07315.07315.3 0.156 Aug-32 K.K[136.11]DQYFLDK[136.11]K[136.11].M sp|Q9UQE7|SMC3_HUMAN 1 1207.6663 0.82 128201 7315 3 1207.661929 403.5627 Structural maintenance of chromosomes protein 3 OS=Homo sapiens OX=9606 GN=SMC3 PE=1 SV=2 8.43 1770 - 623469 - - - -3.6393 - 1.406 0.168 - 114.8 1 2 0 -0.0044 9 0 0 0 1.17E+07 1.43E+07 - - - 1.4388 0.9996 221125_WJC_METTL3_EV_vs_WT_F09.07316.07316.3 0.000213 Sep-56 K.VFLK[136.11]EDTGETHGDTR[166.11].N sp|Q8NEF9|SRFB1_HUMAN 1 1721.8339 1.42 128202 7316 3 1721.833338 574.9519 Serum response factor-binding protein 1 OS=Homo sapiens OX=9606 GN=SRFBP1 PE=1 SV=1 4.75 1770.1 - 190180 - - - -0.3543 - 1.912 0.449 - 79.8 1 2 1 -0.0006 15 0 0 0 4.16E+06 2.93E+06 - - - 5.237 0.9999 221125_WJC_METTL3_EV_vs_WT_F09.07320.07320.3 6.87E-06 Sep-32 K.KDQYFLDKK.M sp|Q9UQE7|SMC3_HUMAN 1 1183.6237 0.82 128204 7320 3 1183.625845 395.5485 Structural maintenance of chromosomes protein 3 OS=Homo sapiens OX=9606 GN=SMC3 PE=1 SV=2 8.43 1770.7 - 309762 - - - 1.792 - 1.901 0.439 - 142.1 1 2 0 0.0021 9 0 0 0 1.19E+07 1.46E+07 - - - 5.3698 0.9457 221125_WJC_METTL3_EV_vs_WT_F09.07321.07321.3 3.92E-06 Oct-52 L.TGR[166.11]DPNDVR[166.11]PIQAR[166.11].L "sp|Q9H307|PININ_HUMAN,tr|G3V5F0|G3V5F0_HUMAN,tr|G3V579|G3V579_HUMAN" 3 1623.8584 2.15 128205 7321 3 1623.858377 542.2934 Pinin OS=Homo sapiens OX=9606 GN=PNN PE=1 SV=5 9.17 1770.8 - 167475 - - - 0.0099 - 1.901 0.429 - 82.5 1 1 1 0 14 0 0 0 7.99E+06 3.71E+06 - - - 5.0301 0.9999 221125_WJC_METTL3_EV_vs_WT_F09.07330.07330.3 4.24E-07 13/44 K.DDDRYEQASDVR.A "sp|O00268|TAF4_HUMAN,tr|A0A0G2JRY5|A0A0G2JRY5_HUMAN" 2 1467.6226 2.06 128210 7330 3 1467.624475 490.2148 Transcription initiation factor TFIID subunit 4 OS=Homo sapiens OX=9606 GN=TAF4 PE=1 SV=2 4.04 1772 - 1.87E+06 - - - 1.268 - 2.171 0.615 - 214.7 1 2 1 0.0019 12 0 0 0 3.77E+07 1.83E+07 - - - 7.5448 0.9553 221125_WJC_METTL3_EV_vs_WT_F09.07331.07331.3 1.43E-06 14/52 L.TGRDPNDVRPIQAR.L "sp|Q9H307|PININ_HUMAN,tr|G3V5F0|G3V5F0_HUMAN,tr|G3V579|G3V579_HUMAN" 3 1593.8336 2.17 128211 7331 3 1593.838088 532.2851 Pinin OS=Homo sapiens OX=9606 GN=PNN PE=1 SV=5 9.17 1772.2 - 335463 - - - 2.8466 - 2.595 0.495 - 163.5 1 1 1 0.0045 14 0 0 0 8.05E+06 3.71E+06 - - - 6.5917 0.9839 221125_WJC_METTL3_EV_vs_WT_F09.07335.07335.3 0.0549 Nov-48 R.DQAEEEPNRIPSR.S sp|Q14676|MDC1_HUMAN 1 1539.7277 1.78 128213 7335 3 1539.730577 514.2499 Mediator of DNA damage checkpoint protein 1 OS=Homo sapiens OX=9606 GN=MDC1 PE=1 SV=3 4.41 1772.7 - 629970 - - - 1.8373 - 1.666 0.26 - 166.2 1 2 1 0.0028 13 0 0 0 3.39E+07 1.91E+07 - - - 2.8219 0.9997 221125_WJC_METTL3_EV_vs_WT_F09.07337.07337.3 2.40E-05 Nov-44 K.DDDR[166.11]YEQASDVR[166.11].A "sp|O00268|TAF4_HUMAN,tr|A0A0G2JRY5|A0A0G2JRY5_HUMAN" 2 1487.6392 2.06 128215 7337 3 1487.640685 496.887 Transcription initiation factor TFIID subunit 4 OS=Homo sapiens OX=9606 GN=TAF4 PE=1 SV=2 4.04 1772.9 - 682409 - - - 1.0291 - 1.782 0.506 - 155.6 1 2 1 0.0015 12 0 0 0 3.76E+07 1.83E+07 - - - 5.7824 0.9951 221125_WJC_METTL3_EV_vs_WT_F09.07341.07341.3 0.00255 Sep-60 K.VASVESQGQEISGNRR.Q "sp|Q5VU43|MYOME_HUMAN,tr|E9PQG4|E9PQG4_HUMAN,tr|A0A087WX83|A0A087WX83_HUMAN,tr|A0A075B749|A0A075B749_HUMAN" 4 1715.8551 3.21 128217 7341 3 1715.857956 572.959 Myomegalin OS=Homo sapiens OX=9606 GN=PDE4DIP PE=1 SV=3 6.11 1773.4 - 149012 - - - 1.6796 - 1.843 0.219 - 118.4 1 2 0 0.0029 16 0 0 0 3.31E+06 1.03E+06 - - - 2.5496 0.9997 221125_WJC_METTL3_EV_vs_WT_F09.07345.07345.3 0.000797 Jul-68 K.YESGPDGGEEDGTGSLKR.S "tr|G3V5R9|G3V5R9_HUMAN,tr|G3V3H3|G3V3H3_HUMAN" 2 1852.8075 2.49 128219 7345 3 1852.810197 618.6098 Kinesin light chain OS=Homo sapiens OX=9606 GN=KLC1 PE=1 SV=1 4.18 1774 - 107931 - - - 1.4475 - 1.432 0.467 - 32 1 2 0 0.0027 18 0 0 0 4.07E+06 1.64E+06 - - - 4.64 0.9987 221125_WJC_METTL3_EV_vs_WT_F09.07347.07347.3 0.000237 Oct-48 R.DQAEEEPNR[166.11]IPSR[166.11].S sp|Q14676|MDC1_HUMAN 1 1559.7443 1.73 128221 7347 3 1559.747593 520.922 Mediator of DNA damage checkpoint protein 1 OS=Homo sapiens OX=9606 GN=MDC1 PE=1 SV=3 4.41 1774.2 - 741001 - - - 2.1189 - 1.987 0.406 - 186.4 1 2 1 0.0033 13 0 0 0 3.18E+07 1.84E+07 - - - 4.9272 0.9762 221125_WJC_METTL3_EV_vs_WT_F09.07350.07350.2 0.000145 Jun-34 R.SGAPPPSGSAVSTAPQPK[136.11].P "sp|Q96SB4|SRPK1_HUMAN,tr|H3BLV9|H3BLV9_HUMAN" 2 1642.8406 1.29 128224 7350 2 1642.838721 822.4276 SRSF protein kinase 1 OS=Homo sapiens OX=9606 GN=SRPK1 PE=1 SV=2 8.47 1774.6 - 67207.8 - - - -1.1438 - 1.284 0.522 - 57 1 1 0 -0.0019 18 0 0 0 6.84E+06 5.30E+06 - - - 3.5105 0.9528 221125_WJC_METTL3_EV_vs_WT_F09.07364.07364.2 0.699 24-Apr K.HEQNIDC[160.03]GGGYVK[136.11].L "sp|P27797|CALR_HUMAN,tr|A0A7P0T861|A0A7P0T861_HUMAN,tr|K7EL50|K7EL50_HUMAN" 3 1483.6605 0.95 128231 7364 2 1483.66362 742.8375 Calreticulin OS=Homo sapiens OX=9606 GN=CALR PE=1 SV=1 5.32 1776.5 - 57807.9 - - - 2.0847 - 0.748 0.253 - 33.8 1 2 0 0.0031 13 0 0 0 1.30E+06 1.36E+06 - - - 0.1635 0.9983 221125_WJC_METTL3_EV_vs_WT_F09.07368.07368.3 1.35E-06 14/56 R.HVAAGTQQPYTDGVR.M sp|P14923|PLAK_HUMAN 1 1598.7801 3.13 128233 7368 3 1598.789339 533.934 Junction plakoglobin OS=Homo sapiens OX=9606 GN=JUP PE=1 SV=3 6.74 1777 - 389720 - - - 5.7675 - 2.647 0.415 - 306.6 1 2 0 0.0092 15 0 0 0 8.44E+06 2.69E+06 - - - 5.7043 1 221125_WJC_METTL3_EV_vs_WT_F09.07369.07369.3 4.10E-05 Sep-60 K.EHGVVPQADNATPSER[166.11].F sp|Q99543|DNJC2_HUMAN 1 1715.8102 1.02 128234 7369 3 1715.811724 572.944 DnaJ homolog subfamily C member 2 OS=Homo sapiens OX=9606 GN=DNAJC2 PE=1 SV=4 4.65 1777.1 - 175182 - - - 0.8614 - 2.254 0.515 - 98.6 1 2 0 0.0015 16 0 0 0 2.02E+07 1.99E+07 - - - 6.3666 0.9996 221125_WJC_METTL3_EV_vs_WT_F09.07379.07379.3 2.09E-05 15/48 K.DGVVEITGKHEER.Q "sp|P04792|HSPB1_HUMAN,tr|A0A6Q8PHJ6|A0A6Q8PHJ6_HUMAN,tr|A0A6Q8PFK8|A0A6Q8PFK8_HUMAN" 3 1467.7318 1.88 128240 7379 3 1467.735036 490.2512 Heat shock protein beta-1 OS=Homo sapiens OX=9606 GN=HSPB1 PE=1 SV=2 4.83 1778.5 - 486682 - - - 2.2245 - 3.09 0.419 - 534.7 1 2 1 0.0033 13 0 0 0 2.19E+07 1.16E+07 - - - 6.2693 0.9998 221125_WJC_METTL3_EV_vs_WT_F09.07384.07384.2 6.99E-07 Oct-34 K.QEAGISEGQGTAGEEEEK[136.11].K "sp|O43583|DENR_HUMAN,tr|F8VVL1|F8VVL1_HUMAN" 2 1855.8163 0.43 128243 7384 2 1855.819795 928.9154 Density-regulated protein OS=Homo sapiens OX=9606 GN=DENR PE=1 SV=2 3.9 1779.2 - 78791.5 - - - 1.886 - 2.031 0.634 - 201.8 1 2 0 0.0035 18 0 0 0 1.46E+06 3.40E+06 - - - 5.4646 0.8179 221125_WJC_METTL3_EV_vs_WT_F09.07387.07387.2 1.46 24-Mar K.HEQNIDC[160.03]GGGYVK.L "sp|P27797|CALR_HUMAN,tr|A0A7P0T861|A0A7P0T861_HUMAN,tr|K7EL50|K7EL50_HUMAN" 3 1475.6463 0.93 128246 7387 2 1475.649344 738.8304 Calreticulin OS=Homo sapiens OX=9606 GN=CALR PE=1 SV=1 5.32 1779.6 - 79355.8 - - - 2.0445 - 0.608 0.196 - 19.9 1 2 0 0.003 13 0 0 0 1.30E+06 1.40E+06 - - - -0.7893 0.9954 221125_WJC_METTL3_EV_vs_WT_F09.07396.07396.3 0.0139 Jul-68 K.QEAGISEGQGTAGEEEEK[136.11].K "sp|O43583|DENR_HUMAN,tr|F8VVL1|F8VVL1_HUMAN" 2 1855.8163 0.1 128250 7396 3 1855.819287 619.6127 Density-regulated protein OS=Homo sapiens OX=9606 GN=DENR PE=1 SV=2 3.9 1780.9 - 100080 - - - 1.6122 - 1.232 0.314 - 51.2 1 2 0 0.003 18 0 0 0 2.89E+05 2.79E+06 - - - 2.5595 0.9995 221125_WJC_METTL3_EV_vs_WT_F09.07397.07397.2 3.51E-06 Jun-34 K.QEAGISEGQGTAGEEEEK.K "sp|O43583|DENR_HUMAN,tr|F8VVL1|F8VVL1_HUMAN" 2 1847.8021 0.43 128251 7397 2 1847.806958 924.9083 Density-regulated protein OS=Homo sapiens OX=9606 GN=DENR PE=1 SV=2 3.9 1781 - 55191 - - - 2.6318 - 1.368 0.63 - 52.8 1 2 0 0.0049 18 0 0 0 1.46E+06 3.40E+06 - - - 4.463 0.9998 221125_WJC_METTL3_EV_vs_WT_F09.07398.07398.3 5.86E-07 17/44 R.HGFEAASIK[136.11]EER[166.11].G "sp|P35580|MYH10_HUMAN,tr|E7ERA5|E7ERA5_HUMAN" 2 1390.696 1 128252 7398 3 1390.700358 464.5726 Myosin-10 OS=Homo sapiens OX=9606 GN=MYH10 PE=1 SV=3 5.5 1781.1 - 427222 - - - 3.1351 - 3.034 0.583 - 490.6 1 2 1 0.0044 12 0 0 0 8.21E+07 8.25E+07 - - - 8.1151 0.9989 221125_WJC_METTL3_EV_vs_WT_F09.07400.07400.3 0.000906 Nov-36 R.HRNEVTVELR.K sp|O00505|IMA4_HUMAN 1 1251.6684 1.14 128254 7400 3 1251.670041 418.2301 Importin subunit alpha-4 OS=Homo sapiens OX=9606 GN=KPNA3 PE=1 SV=2 6.76 1781.4 - 125016 - - - 1.3246 - 2.018 0.361 - 267.5 1 2 1 0.0017 10 0 0 0 3.01E+07 2.64E+07 - - - 4.6148 0.9995 221125_WJC_METTL3_EV_vs_WT_F09.07402.07402.3 5.03E-05 14/52 K.K[136.11]GPGEVAGTVTGQK[136.11].R "sp|Q86U44|MTA70_HUMAN,tr|F5H6D8|F5H6D8_HUMAN,tr|H0YFV6|H0YFV6_HUMAN,tr|B4DTN4|B4DTN4_HUMAN" 4 1343.738 0.23 128255 7402 3 1343.744825 448.9199 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 8.59 1781.6 - 1.31E+06 - - - 5.0947 - 2.751 0.478 - 311 1 2 0 0.0068 14 0 0 0 3.58E+07 1.56E+08 - - - 6.5567 0.9985 221125_WJC_METTL3_EV_vs_WT_F09.07404.07404.2 0.000853 16-Aug K.QDSGHLDLR[166.11].N "sp|Q86U44|MTA70_HUMAN,tr|B4E349|B4E349_HUMAN,tr|F5H6D8|F5H6D8_HUMAN,tr|B4DTN4|B4DTN4_HUMAN" 4 1049.5129 0.02 128257 7404 2 1049.515786 525.7637 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 5.21 1781.8 - 940327 - - - 2.7108 - 1.644 0.374 - 192.7 1 2 0 0.0028 9 0 0 0 2.50E+06 1.64E+08 - - - 3.2407 0.7978 221125_WJC_METTL3_EV_vs_WT_F09.07408.07408.2 0.811 14-Aug Q.DSGHLDLR[166.11].N "sp|Q86U44|MTA70_HUMAN,tr|B4E349|B4E349_HUMAN,tr|F5H6D8|F5H6D8_HUMAN,tr|B4DTN4|B4DTN4_HUMAN" 4 921.4544 0.03 128259 7408 2 921.45694 461.7345 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 5.21 1782.4 - 475357 - - - 2.7956 - 1.853 0.192 - 259 1 1 0 0.0026 8 0 0 0 1.17E+06 4.46E+07 - - - 2.3186 0.9635 221125_WJC_METTL3_EV_vs_WT_F09.07409.07409.3 0.00764 Dec-48 K.IQDK[136.11]EGIPPDQQR[166.11].L "sp|P62979|RS27A_HUMAN,sp|P0CG48|UBC_HUMAN,sp|P0CG48|UBC_HUMAN,sp|P0CG48|UBC_HUMAN,sp|P0CG48|UBC_HUMAN,sp|P0CG48|UBC_HUMAN,sp|P0CG48|UBC_HUMAN,sp|P0CG48|UBC_HUMAN,sp|P0CG48|UBC_HUMAN,sp|P0CG48|UBC_HUMAN,sp|P0CG47|UBB_HUMAN,sp|P0CG47|UBB_HUMAN,sp|P0CG47|UBB_HUMAN,sp|P62987|RL40_HUMAN,tr|F5H388|F5H388_HUMAN,tr|F5H388|F5H388_HUMAN,tr|F5GYU3|F5GYU3_HUMAN,tr|F5GYU3|F5GYU3_HUMAN,tr|B4DV12|B4DV12_HUMAN,tr|B4DV12|B4DV12_HUMAN,tr|J3QSA3|J3QSA3_HUMAN,tr|Q5PY61|Q5PY61_HUMAN,tr|Q5PY61|Q5PY61_HUMAN,tr|Q5PY61|Q5PY61_HUMAN,tr|F5H2Z3|F5H2Z3_HUMAN,tr|F5H2Z3|F5H2Z3_HUMAN,tr|M0R2S1|M0R2S1_HUMAN,tr|J3QS39|J3QS39_HUMAN,tr|J3QTR3|J3QTR3_HUMAN,tr|Q96C32|Q96C32_HUMAN,tr|Q96C32|Q96C32_HUMAN,tr|Q96C32|Q96C32_HUMAN,tr|Q96C32|Q96C32_HUMAN,tr|M0R1V7|M0R1V7_HUMAN,tr|F5H747|F5H747_HUMAN,tr|F5H747|F5H747_HUMAN,tr|F5GXK7|F5GXK7_HUMAN,tr|F5GXK7|F5GXK7_HUMAN,tr|M0R1M6|M0R1M6_HUMAN,tr|F5H6Q2|F5H6Q2_HUMAN,tr|F5H6Q2|F5H6Q2_HUMAN,tr|F5GZ39|F5GZ39_HUMAN,tr|J3QKN0|J3QKN0_HUMAN,tr|J3QKN0|J3QKN0_HUMAN,tr|F5H265|F5H265_HUMAN,tr|F5H265|F5H265_HUMAN,tr|A0A2R8Y422|A0A2R8Y422_HUMAN" 47 1540.7964 0.6 128260 7409 3 1540.800083 514.6061 Ubiquitin-40S ribosomal protein S27a OS=Homo sapiens OX=9606 GN=RPS27A PE=1 SV=2 4.56 1782.5 - 356141 - - - 2.3644 - 1.821 0.209 - 222 1 2 1 0.0036 13 0 0 0 5.62E+06 9.41E+06 - - - 2.4942 1 221125_WJC_METTL3_EV_vs_WT_F09.07410.07410.3 1.73E-09 20/44 R.HGFEAASIKEER.G "sp|P35580|MYH10_HUMAN,tr|E7ERA5|E7ERA5_HUMAN" 2 1372.6735 0.99 128261 7410 3 1372.677548 458.5651 Myosin-10 OS=Homo sapiens OX=9606 GN=MYH10 PE=1 SV=3 5.5 1782.6 - 804150 - - - 2.9286 - 3.527 0.615 - 684.4 1 2 1 0.004 12 0 0 0 8.19E+07 8.24E+07 - - - 8.8893 0.9712 221125_WJC_METTL3_EV_vs_WT_F09.07417.07417.3 0.0522 Oct-44 R.HELQGQK[136.11]PLLEH.- "sp|Q9NRY5|F1142_HUMAN,tr|E7ESJ7|E7ESJ7_HUMAN" 2 1435.7663 1.11 128266 7417 3 1435.770348 479.596 Protein FAM114A2 OS=Homo sapiens OX=9606 GN=FAM114A2 PE=1 SV=4 6 1783.6 - 353309 - - - 2.8103 - 1.432 0.211 - 114.7 1 2 0 0.004 12 0 0 0 1.20E+07 1.08E+07 - - - 1.8866 0.9998 221125_WJC_METTL3_EV_vs_WT_F09.07419.07419.3 0.000242 Sep-52 R.VNVC[160.03]EHC[160.03]LVANHAK.C "sp|O95159|ZFPL1_HUMAN,tr|E9PJX1|E9PJX1_HUMAN,tr|E9PNY1|E9PNY1_HUMAN,tr|E9PMQ3|E9PMQ3_HUMAN,tr|E9PJ47|E9PJ47_HUMAN,tr|E9PQ47|E9PQ47_HUMAN" 6 1649.7766 0.64 128268 7419 3 1649.779039 550.9328 Zinc finger protein-like 1 OS=Homo sapiens OX=9606 GN=ZFPL1 PE=1 SV=2 6.88 1783.8 - 211561 - - - 1.4602 - 1.704 0.43 - 55.9 1 2 0 0.0024 14 0 0 0 9.27E+06 1.44E+07 - - - 4.7498 0.9999 221125_WJC_METTL3_EV_vs_WT_F09.07420.07420.2 1.49E-07 22-Nov R.QQQQQQQEQLYK[136.11].M sp|Q5JSZ5|PRC2B_HUMAN 1 1583.7783 1.59 128269 7420 2 1583.775739 792.8964 Protein PRRC2B OS=Homo sapiens OX=9606 GN=PRRC2B PE=1 SV=2 6 1783.9 - 107512 - - - -1.6385 - 2.285 0.582 - 523.7 1 2 0 -0.0026 12 0 0 0 1.94E+07 1.22E+07 - - - 5.5131 0.9996 221125_WJC_METTL3_EV_vs_WT_F09.07424.07424.4 0.00645 Sep-78 R.VNVC[160.03]EHC[160.03]LVANHAK[136.11].C "sp|O95159|ZFPL1_HUMAN,tr|E9PJX1|E9PJX1_HUMAN,tr|E9PNY1|E9PNY1_HUMAN,tr|E9PMQ3|E9PMQ3_HUMAN,tr|E9PJ47|E9PJ47_HUMAN,tr|E9PQ47|E9PQ47_HUMAN" 6 1657.7908 1.49 128271 7424 4 1657.792846 415.455 Zinc finger protein-like 1 OS=Homo sapiens OX=9606 GN=ZFPL1 PE=1 SV=2 6.88 1784.5 - 310058 - - - 1.2161 - 1.707 0.351 - 51.5 1 2 0 0.002 14 0 0 0 1.23E+07 8.31E+06 - - - 2.4752 0.9689 221125_WJC_METTL3_EV_vs_WT_F09.07433.07433.2 0.39 14-Jul R.STLEPVEK[136.11].A "sp|P48741|HSP77_HUMAN,sp|P0DMV8|HS71A_HUMAN,sp|P0DMV9|HS71B_HUMAN,sp|P17066|HSP76_HUMAN,tr|V9GZ37|V9GZ37_HUMAN,tr|A0A0G2JIW1|A0A0G2JIW1_HUMAN" 6 909.4899 0.25 128278 7433 2 909.492851 455.7522 Putative heat shock 70 kDa protein 7 OS=Homo sapiens OX=9606 GN=HSPA7 PE=5 SV=2 4.53 1785.8 - 326256 - - - 3.2854 - 1.356 0.143 - 183.9 1 2 0 0.003 8 0 0 0 2.49E+06 9.83E+06 - - - 1.0147 0.996 221125_WJC_METTL3_EV_vs_WT_F09.07436.07436.4 0.00417 Oct-66 R.R[166.11]YDDPEVQK[136.11]DIK[136.11].N "sp|P38646|GRP75_HUMAN,tr|H0Y8K0|H0Y8K0_HUMAN,tr|A0A7I2V2S7|A0A7I2V2S7_HUMAN,tr|A0A7I2V2G2|A0A7I2V2G2_HUMAN,tr|A0A3B3ITI4|A0A3B3ITI4_HUMAN,tr|A0A7I2V3F7|A0A7I2V3F7_HUMAN,tr|A0A7I2YQB2|A0A7I2YQB2_HUMAN,tr|D6RCD7|D6RCD7_HUMAN" 8 1530.7888 0.001 128279 7436 4 1530.790038 383.7045 "Stress-70 protein, mitochondrial OS=Homo sapiens OX=9606 GN=HSPA9 PE=1 SV=2" 4.68 1786.2 - 286435 - - - 0.7813 - 1.74 0.3 - 89.6 1 2 1 0.0012 12 0 0 0 0.00E+00 1.08E+07 - - - 2.0465 0.9996 221125_WJC_METTL3_EV_vs_WT_F09.07439.07439.3 3.15E-05 Nov-44 R.RYDDPEVQKDIK.N "sp|P38646|GRP75_HUMAN,tr|H0Y8K0|H0Y8K0_HUMAN,tr|A0A7I2V2S7|A0A7I2V2S7_HUMAN,tr|A0A7I2V2G2|A0A7I2V2G2_HUMAN,tr|A0A3B3ITI4|A0A3B3ITI4_HUMAN,tr|A0A7I2V3F7|A0A7I2V3F7_HUMAN,tr|A0A7I2YQB2|A0A7I2YQB2_HUMAN,tr|D6RCD7|D6RCD7_HUMAN" 8 1504.7522 0.42 128280 7439 3 1504.75496 502.5913 "Stress-70 protein, mitochondrial OS=Homo sapiens OX=9606 GN=HSPA9 PE=1 SV=2" 4.68 1786.6 - 223454 - - - 1.8528 - 2.091 0.474 - 174.4 1 2 1 0.0028 12 0 0 0 1.46E+07 3.47E+07 - - - 5.8685 0.9998 221125_WJC_METTL3_EV_vs_WT_F09.07446.07446.3 2.62E-07 16/44 R.R[166.11]YDDPEVQK[136.11]DIK[136.11].N "sp|P38646|GRP75_HUMAN,tr|H0Y8K0|H0Y8K0_HUMAN,tr|A0A7I2V2S7|A0A7I2V2S7_HUMAN,tr|A0A7I2V2G2|A0A7I2V2G2_HUMAN,tr|A0A3B3ITI4|A0A3B3ITI4_HUMAN,tr|A0A7I2V3F7|A0A7I2V3F7_HUMAN,tr|A0A7I2YQB2|A0A7I2YQB2_HUMAN,tr|D6RCD7|D6RCD7_HUMAN" 8 1530.7888 0.41 128283 7446 3 1530.792194 511.2702 "Stress-70 protein, mitochondrial OS=Homo sapiens OX=9606 GN=HSPA9 PE=1 SV=2" 4.68 1787.6 - 756429 - - - 2.1897 - 3.059 0.495 - 406.1 1 2 1 0.0034 12 0 0 0 1.47E+07 3.60E+07 - - - 7.157 0.9997 221125_WJC_METTL3_EV_vs_WT_F09.07447.07447.3 3.36E-05 14/52 R.QSEVPK[136.11]PEDGEPPR[166.11].R "sp|Q9Y520|PRC2C_HUMAN,tr|E7EPN9|E7EPN9_HUMAN" 2 1581.7754 1.09 128284 7447 3 1581.78013 528.2657 Protein PRRC2C OS=Homo sapiens OX=9606 GN=PRRC2C PE=1 SV=4 4.41 1787.7 - 520558 - - - 3.0093 - 2.173 0.431 - 167.8 1 2 0 0.0048 14 0 0 0 1.97E+07 1.81E+07 - - - 5.4064 0.9998 221125_WJC_METTL3_EV_vs_WT_F09.07453.07453.2 1.37E-07 22-Oct R.QQQQQQQEQLYK.M sp|Q5JSZ5|PRC2B_HUMAN 1 1575.7641 1.59 128289 7453 2 1575.767038 788.8893 Protein PRRC2B OS=Homo sapiens OX=9606 GN=PRRC2B PE=1 SV=2 6 1788.4 - 850963 - - - 1.8429 - 2.442 0.541 - 344.9 1 2 0 0.0029 12 0 0 0 1.94E+07 1.22E+07 - - - 5.3851 1 221125_WJC_METTL3_EV_vs_WT_F09.07455.07455.2 1.15E-10 17/30 R.SGGGGGGGLGSGGSIR.S sp|P35527|K1C9_HUMAN 1 1231.5905 999 128290 7455 2 1231.592997 616.8025 "Keratin, type I cytoskeletal 9 OS=Homo sapiens OX=9606 GN=KRT9 PE=1 SV=3" 9.47 1788.7 - 1.10E+06 - - - 2.0063 - 3.527 0.574 - 857.5 1 2 0 0.0025 16 0 0 0 2.65E+07 0.00E+00 - - - 6.3787 1 221125_WJC_METTL3_EV_vs_WT_F09.07469.07469.2 5.12E-05 19/26 K.K[136.11]GPGEVAGTVTGQK[136.11].R "sp|Q86U44|MTA70_HUMAN,tr|F5H6D8|F5H6D8_HUMAN,tr|H0YFV6|H0YFV6_HUMAN,tr|B4DTN4|B4DTN4_HUMAN" 4 1343.738 0.001 128299 7469 2 1343.742753 672.8763 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 8.59 1790.5 - 407853 - - - 3.5528 - 3.7 0.535 - 910.1 1 2 0 0.0048 14 0 0 0 0.00E+00 1.23E+07 - - - 6.2742 0.9794 221125_WJC_METTL3_EV_vs_WT_F09.07473.07473.3 0.000778 13/68 K.EATPVVHETEPESGSQPR.P "sp|Q9Y520|PRC2C_HUMAN,tr|E7EPN9|E7EPN9_HUMAN" 2 1948.9126 1.42 128301 7473 3 1948.921356 650.6448 Protein PRRC2C OS=Homo sapiens OX=9606 GN=PRRC2C PE=1 SV=4 4.48 1791.1 - 149598 - - - 4.4676 - 2.521 0.574 - 195.4 1 1 0 0.0087 18 0 0 0 2.99E+07 2.10E+07 - - - 7.2396 0.9947 221125_WJC_METTL3_EV_vs_WT_F09.07475.07475.3 1.20E-05 Oct-68 K.EATPVVHETEPESGSQPR[166.11].P "sp|Q9Y520|PRC2C_HUMAN,tr|E7EPN9|E7EPN9_HUMAN" 2 1958.9209 1.42 128302 7475 3 1958.92352 653.9809 Protein PRRC2C OS=Homo sapiens OX=9606 GN=PRRC2C PE=1 SV=4 4.48 1791.3 - 116114 - - - 1.3278 - 2.107 0.52 - 116.5 1 1 0 0.0026 18 0 0 0 2.99E+07 2.10E+07 - - - 6.1925 1 221125_WJC_METTL3_EV_vs_WT_F09.07488.07488.3 1.98E-05 17/48 R.HLADHGQLSGIQR.A sp|O60783|RT14_HUMAN 1 1430.7379 1.59 128309 7488 3 1430.741697 477.9199 "28S ribosomal protein S14, mitochondrial OS=Homo sapiens OX=9606 GN=MRPS14 PE=1 SV=1" 6.92 1793 - 2.20E+06 - - - 2.6825 - 3.166 0.537 - 327.7 1 2 0 0.0038 13 0 0 0 1.44E+08 9.02E+07 - - - 7.6506 0.9997 221125_WJC_METTL3_EV_vs_WT_F09.07490.07490.3 0.00423 15/40 K.DSELDKHLESR.V "sp|O75688|PPM1B_HUMAN,tr|B8ZZF0|B8ZZF0_HUMAN,tr|A0A3B3IS24|A0A3B3IS24_HUMAN,tr|C9JIR6|C9JIR6_HUMAN" 4 1327.6368 3.19 128311 7490 3 1327.640155 443.5529 Protein phosphatase 1B OS=Homo sapiens OX=9606 GN=PPM1B PE=1 SV=1 4.75 1793.3 - 877842 - - - 2.521 - 2.707 0.51 - 480.3 1 2 1 0.0033 11 0 0 0 1.25E+09 3.93E+08 - - - 7.0541 0.9998 221125_WJC_METTL3_EV_vs_WT_F09.07491.07491.3 1.36E-05 Nov-60 R.DPALNSGVSQKPDPAK.T sp|P11388|TOP2A_HUMAN 1 1622.8264 1.52 128312 7491 3 1622.832174 541.9494 DNA topoisomerase 2-alpha OS=Homo sapiens OX=9606 GN=TOP2A PE=1 SV=3 5.96 1793.4 - 268113 - - - 3.558 - 2.31 0.521 - 157.2 1 2 0 0.0058 16 0 0 0 1.57E+07 1.03E+07 - - - 6.4953 0.9999 221125_WJC_METTL3_EV_vs_WT_F09.07492.07492.3 1.60E-05 Nov-60 R.DPALNSGVSQK[136.11]PDPAK[136.11].T sp|P11388|TOP2A_HUMAN 1 1638.8548 1.51 128313 7492 3 1638.858758 547.2922 DNA topoisomerase 2-alpha OS=Homo sapiens OX=9606 GN=TOP2A PE=1 SV=3 5.96 1793.5 - 205623 - - - 2.4151 - 2.455 0.48 - 153.7 1 2 0 0.004 16 0 0 0 1.56E+07 1.03E+07 - - - 6.1949 0.9999 221125_WJC_METTL3_EV_vs_WT_F09.07497.07497.3 2.06E-08 15/44 R.KQVSSHIQVLAR.R "sp|Q15562|TEAD2_HUMAN,sp|P28347|TEAD1_HUMAN,sp|Q15561|TEAD4_HUMAN,sp|Q99594|TEAD3_HUMAN,tr|A0A1X7SBS4|A0A1X7SBS4_HUMAN,tr|Q53GI4|Q53GI4_HUMAN,tr|H0YE88|H0YE88_HUMAN,tr|H0YG62|H0YG62_HUMAN,tr|H0YGS2|H0YGS2_HUMAN,tr|H0YEJ9|H0YEJ9_HUMAN,tr|A0A0A0MRF3|A0A0A0MRF3_HUMAN,tr|A0A7P0SNI2|A0A7P0SNI2_HUMAN" 12 1364.7888 0.99 128315 7497 3 1364.794367 455.9369 Transcriptional enhancer factor TEF-4 OS=Homo sapiens OX=9606 GN=TEAD2 PE=1 SV=2 11 1794.2 - 412944 - - - 4.0556 - 3.163 0.58 - 382.3 1 2 0 0.0055 12 0 0 0 3.75E+07 3.77E+07 - - - 8.1967 0.9997 221125_WJC_METTL3_EV_vs_WT_F09.07504.07504.3 0.0163 Nov-60 K.ELHNTPYGTASEPSEK.A sp|Q9NXV2|KCTD5_HUMAN 1 1758.8061 4.79 128319 7504 3 1758.80582 587.276 BTB\POZ domain-containing protein KCTD5 OS=Homo sapiens OX=9606 GN=KCTD5 PE=1 SV=1 4.75 1795 - 392375 - - - -0.1353 - 1.616 0.405 - 113.6 1 2 0 -0.0002 16 0 0 0 6.64E+08 1.39E+08 - - - 4.2868 1 221125_WJC_METTL3_EV_vs_WT_F09.07505.07505.3 3.74E-07 18/48 R.HLADHGQLSGIQR[166.11].A sp|O60783|RT14_HUMAN 1 1440.7461 1.59 128320 7505 3 1440.748736 481.256 "28S ribosomal protein S14, mitochondrial OS=Homo sapiens OX=9606 GN=MRPS14 PE=1 SV=1" 6.92 1795 - 2.95E+06 - - - 1.8095 - 2.996 0.59 - 367 1 2 0 0.0026 13 0 0 0 1.44E+08 9.01E+07 - - - 8.0922 0.9967 221125_WJC_METTL3_EV_vs_WT_F09.07507.07507.2 0.00132 20-Aug K.DSELDKHLESR.V "sp|O75688|PPM1B_HUMAN,tr|B8ZZF0|B8ZZF0_HUMAN,tr|A0A3B3IS24|A0A3B3IS24_HUMAN,tr|C9JIR6|C9JIR6_HUMAN" 4 1327.6368 3.69 128322 7507 2 1327.635048 664.8257 Protein phosphatase 1B OS=Homo sapiens OX=9606 GN=PPM1B PE=1 SV=1 4.75 1795.3 - 104599 - - - -1.3257 - 1.783 0.459 - 270.4 1 2 1 -0.0018 11 0 0 0 6.86E+07 1.86E+07 - - - 3.9951 0.9979 221125_WJC_METTL3_EV_vs_WT_F09.07513.07513.3 0.0466 Dec-44 R.K[136.11]QVSSHIQVLAR[166.11].R "sp|Q15562|TEAD2_HUMAN,sp|P28347|TEAD1_HUMAN,sp|Q15561|TEAD4_HUMAN,sp|Q99594|TEAD3_HUMAN,tr|A0A1X7SBS4|A0A1X7SBS4_HUMAN,tr|Q53GI4|Q53GI4_HUMAN,tr|H0YE88|H0YE88_HUMAN,tr|H0YG62|H0YG62_HUMAN,tr|H0YGS2|H0YGS2_HUMAN,tr|H0YEJ9|H0YEJ9_HUMAN,tr|A0A0A0MRF3|A0A0A0MRF3_HUMAN,tr|A0A7P0SNI2|A0A7P0SNI2_HUMAN" 12 1382.8113 1.01 128326 7513 3 1382.81392 461.9444 Transcriptional enhancer factor TEF-4 OS=Homo sapiens OX=9606 GN=TEAD2 PE=1 SV=2 11 1796.1 - 784192 - - - 1.8932 - 1.744 0.28 - 202.8 1 2 0 0.0026 12 0 0 0 3.74E+07 3.72E+07 - - - 3.2026 0.9548 221125_WJC_METTL3_EV_vs_WT_F09.07520.07520.3 0.000222 Dec-56 F.RGFSSGSAVVSGGSR.R sp|P35908|K22E_HUMAN 1 1409.7011 302.16 128329 7520 3 1409.704111 470.9077 "Keratin, type II cytoskeletal 2 epidermal OS=Homo sapiens OX=9606 GN=KRT2 PE=1 SV=2" 12 1797 - 4.43E+06 - - - 2.1075 - 1.918 0.382 - 174.4 1 1 0 0.003 15 0 0 0 1.32E+08 4.38E+05 - - - 4.4975 0.9994 221125_WJC_METTL3_EV_vs_WT_F09.07522.07522.3 5.25E-05 Nov-60 K.ELHNTPYGTASEPSEK[136.11].A sp|Q9NXV2|KCTD5_HUMAN 1 1766.8203 4.78 128331 7522 3 1766.826078 589.9474 BTB\POZ domain-containing protein KCTD5 OS=Homo sapiens OX=9606 GN=KCTD5 PE=1 SV=1 4.75 1797.2 - 337834 - - - 3.2941 - 1.86 0.428 - 91.5 1 2 0 0.0058 16 0 0 0 6.63E+08 1.39E+08 - - - 4.9025 0.9995 221125_WJC_METTL3_EV_vs_WT_F09.07531.07531.3 7.32E-05 Aug-36 K.NHEEEMNALR.G "sp|Q04695|K1C17_HUMAN,sp|P02533|K1C14_HUMAN,tr|K7EPJ9|K7EPJ9_HUMAN,tr|K7ESE1|K7ESE1_HUMAN,tr|F5GWP8|F5GWP8_HUMAN" 5 1241.5459 13.98 128335 7531 3 1241.54894 414.8559 "Keratin, type I cytoskeletal 17 OS=Homo sapiens OX=9606 GN=KRT17 PE=1 SV=2" 4.75 1798.4 - 174747 - - - 2.4614 - 1.501 0.44 - 126.6 1 2 0 0.0031 10 0 0 0 5.15E+06 3.69E+05 - - - 4.6308 0.9999 221125_WJC_METTL3_EV_vs_WT_F09.07538.07538.3 6.56E-06 13/40 K.DSELDK[136.11]HLESR[166.11].V "sp|O75688|PPM1B_HUMAN,tr|B8ZZF0|B8ZZF0_HUMAN,tr|A0A3B3IS24|A0A3B3IS24_HUMAN,tr|C9JIR6|C9JIR6_HUMAN" 4 1345.6593 3.2 128337 7538 3 1345.660677 449.5604 Protein phosphatase 1B OS=Homo sapiens OX=9606 GN=PPM1B PE=1 SV=1 4.75 1799.4 - 7.66E+06 - - - 1.0396 - 2.549 0.5 - 475.3 1 2 1 0.0014 11 0 0 0 1.26E+09 3.93E+08 - - - 6.7723 0.997 221125_WJC_METTL3_EV_vs_WT_F09.07539.07539.2 0.000688 20-Nov K.DSELDK[136.11]HLESR[166.11].V "sp|O75688|PPM1B_HUMAN,tr|B8ZZF0|B8ZZF0_HUMAN,tr|A0A3B3IS24|A0A3B3IS24_HUMAN,tr|C9JIR6|C9JIR6_HUMAN" 4 1345.6593 3.69 128338 7539 2 1345.660078 673.8369 Protein phosphatase 1B OS=Homo sapiens OX=9606 GN=PPM1B PE=1 SV=1 4.75 1799.5 - 379596 - - - 0.5945 - 2.202 0.361 - 552.7 1 2 1 0.0008 11 0 0 0 6.86E+07 1.86E+07 - - - 3.8425 0.9998 221125_WJC_METTL3_EV_vs_WT_F09.07541.07541.2 4.88E-07 30-Sep K.ELHNTPYGTASEPSEK.A sp|Q9NXV2|KCTD5_HUMAN 1 1758.8061 6.2 128340 7541 2 1758.806019 880.4103 BTB\POZ domain-containing protein KCTD5 OS=Homo sapiens OX=9606 GN=KCTD5 PE=1 SV=1 4.75 1799.8 - 151688 - - - -0.0222 - 1.978 0.429 - 140.2 1 2 0 0 16 0 0 0 2.73E+07 4.40E+06 - - - 3.8865 0.9982 221125_WJC_METTL3_EV_vs_WT_F09.07542.07542.3 4.26E-06 Sep-52 R.AK[136.11]EEQQDDTVYMGK[136.11].V "sp|Q14203|DCTN1_HUMAN,tr|A0A804CDA6|A0A804CDA6_HUMAN,tr|E7EX90|E7EX90_HUMAN,tr|A0A7P0Z4C3|A0A7P0Z4C3_HUMAN,tr|E7EWF7|E7EWF7_HUMAN" 5 1656.7636 16.11 128341 7542 3 1656.758902 553.2618 Dynactin subunit 1 OS=Homo sapiens OX=9606 GN=DCTN1 PE=1 SV=3 4.32 1799.9 - 136995 - - - -2.8363 - 1.685 0.458 - 101.8 1 2 1 -0.0047 14 0 0 0 5.97E+08 3.71E+07 - - - 5.0316 1 221125_WJC_METTL3_EV_vs_WT_F09.07549.07549.3 1.29E-06 13/52 R.AKEEQQDDTVYMGK.V "sp|Q14203|DCTN1_HUMAN,tr|A0A804CDA6|A0A804CDA6_HUMAN,tr|E7EX90|E7EX90_HUMAN,tr|A0A7P0Z4C3|A0A7P0Z4C3_HUMAN,tr|E7EWF7|E7EWF7_HUMAN" 5 1640.7352 16.09 128344 7549 3 1640.733713 547.919 Dynactin subunit 1 OS=Homo sapiens OX=9606 GN=DCTN1 PE=1 SV=3 4.32 1800.9 - 440400 - - - -0.9069 - 2.833 0.653 - 239.5 1 2 1 -0.0015 14 0 0 0 5.97E+08 3.71E+07 - - - 8.5873 0.9999 221125_WJC_METTL3_EV_vs_WT_F09.07557.07557.3 7.55E-07 19/44 R.NK[136.11]FNQVESDK[136.11]LR[166.11].M sp|Q10471|GALT2_HUMAN 1 1502.8052 1.2 128348 7557 3 1502.805776 501.9423 Polypeptide N-acetylgalactosaminyltransferase 2 OS=Homo sapiens OX=9606 GN=GALNT2 PE=1 SV=1 8.59 1801.9 - 825950 - - - 0.4092 - 2.929 0.513 - 646.1 1 2 2 0.0006 12 0 0 0 1.02E+08 8.49E+07 - - - 7.2381 0.9992 221125_WJC_METTL3_EV_vs_WT_F09.07563.07563.2 0.0197 30-Jun K.ELHNTPYGTASEPSEK[136.11].A sp|Q9NXV2|KCTD5_HUMAN 1 1766.8203 6.2 128349 7563 2 1766.821512 884.4174 BTB\POZ domain-containing protein KCTD5 OS=Homo sapiens OX=9606 GN=KCTD5 PE=1 SV=1 4.75 1802.8 - 76009.2 - - - 0.7097 - 1.329 0.397 - 35.7 1 2 0 0.0013 16 0 0 0 2.73E+07 4.40E+06 - - - 2.6721 0.9537 221125_WJC_METTL3_EV_vs_WT_F09.07566.07566.3 0.406 Oct-44 R.SQYEQLAEQNRK.D "sp|P13645|K1C10_HUMAN,tr|A0A1B0GVI3|A0A1B0GVI3_HUMAN" 2 1492.727 22.74 128350 7566 3 1492.723756 498.5829 "Keratin, type I cytoskeletal 10 OS=Homo sapiens OX=9606 GN=KRT10 PE=1 SV=6" 5.86 1803.2 - 543603 - - - -2.1866 - 1.566 0.137 - 113.8 1 2 0 -0.0033 12 0 0 0 6.14E+07 2.70E+06 - - - 1.3098 0.9999 221125_WJC_METTL3_EV_vs_WT_F09.07571.07571.3 6.85E-07 20/44 R.NKFNQVESDKLR.M sp|Q10471|GALT2_HUMAN 1 1476.7685 1.21 128353 7571 3 1476.767366 493.2634 Polypeptide N-acetylgalactosaminyltransferase 2 OS=Homo sapiens OX=9606 GN=GALNT2 PE=1 SV=1 8.59 1803.8 - 1.95E+06 - - - -0.7618 - 3.03 0.555 - 689 1 2 2 -0.0011 12 0 0 0 1.01E+08 8.36E+07 - - - 7.8002 0.9582 221125_WJC_METTL3_EV_vs_WT_F09.07586.07586.2 0.0206 26-Jul R.AKEEQQDDTVYMGK.V "sp|Q14203|DCTN1_HUMAN,tr|A0A804CDA6|A0A804CDA6_HUMAN,tr|E7EX90|E7EX90_HUMAN,tr|A0A7P0Z4C3|A0A7P0Z4C3_HUMAN,tr|E7EWF7|E7EWF7_HUMAN" 5 1640.7352 2.81 128362 7586 2 1640.72789 821.3749 Dynactin subunit 1 OS=Homo sapiens OX=9606 GN=DCTN1 PE=1 SV=3 4.32 1805.6 - 141982 - - - -4.4559 - 1.512 0.474 - 121.8 1 2 1 -0.0073 14 0 0 0 3.83E+06 1.36E+06 - - - 3.5772 1 221125_WJC_METTL3_EV_vs_WT_F09.07595.07595.3 6.99E-11 20/64 M.PSETPQAEVGPTGC[160.03]PHR[166.11].S "sp|P35520|CBS_HUMAN,tr|C9JMA6|C9JMA6_HUMAN" 2 1828.8402 0.63 128367 7595 3 1828.839033 610.6207 Cystathionine beta-synthase OS=Homo sapiens OX=9606 GN=CBS PE=1 SV=2 5.41 1806.6 - 587609 - - - -0.6195 - 3.941 0.577 - 655.3 1 2 0 -0.0011 17 0 0 0 2.59E+07 4.11E+07 - - - 8.4373 0.9999 221125_WJC_METTL3_EV_vs_WT_F09.07606.07606.2 0.000267 30-Aug K.HSGPNSADSANDGFVR.L sp|P52597|HNRPF_HUMAN 1 1629.7132 0.79 128374 7606 2 1629.712123 815.8639 Heterogeneous nuclear ribonucleoprotein F OS=Homo sapiens OX=9606 GN=HNRNPF PE=1 SV=3 5.21 1808.1 - 264114 - - - -0.6369 - 2.055 0.587 - 140.5 1 2 0 -0.001 16 0 0 0 3.27E+07 4.15E+07 - - - 5.1471 0.9999 221125_WJC_METTL3_EV_vs_WT_F09.07609.07609.3 2.72E-06 14/60 K.VMQQQQQTTQQQLPQK.V sp|Q15459|SF3A1_HUMAN 1 1940.9738 0.89 128375 7609 3 1940.973254 647.9985 Splicing factor 3A subunit 1 OS=Homo sapiens OX=9606 GN=SF3A1 PE=1 SV=1 8.72 1808.5 - 460937 - - - -0.2859 - 1.994 0.495 - 202 1 2 0 -0.0006 16 0 0 0 9.43E+06 1.06E+07 - - - 5.8294 1 221125_WJC_METTL3_EV_vs_WT_F09.07617.07617.3 5.06E-08 22/64 M.PSETPQAEVGPTGC[160.03]PHR.S "sp|P35520|CBS_HUMAN,tr|C9JMA6|C9JMA6_HUMAN" 2 1818.8319 0.63 128380 7617 3 1818.831601 607.2846 Cystathionine beta-synthase OS=Homo sapiens OX=9606 GN=CBS PE=1 SV=2 5.41 1809.4 - 725865 - - - -0.1622 - 3.323 0.613 - 534.3 1 2 0 -0.0003 17 0 0 0 2.57E+07 4.11E+07 - - - 8.408 0.9952 221125_WJC_METTL3_EV_vs_WT_F09.07618.07618.4 473 Feb-96 -.MGC[160.03]C[160.03]GC[160.03]SGGC[160.03]GSGC[160.03]GGR.G sp|Q701N2|KRA55_HUMAN 1 1735.5412 0.68 128381 7618 4 1736.542906 434.8926 Keratin-associated protein 5-5 OS=Homo sapiens OX=9606 GN=KRTAP5-5 PE=2 SV=2 7.61 1809.6 - 538820 - - - 577.1894 - 0.485 0.476 - 2.4 1 2 0 1.0017 17 0 0 0 1.93E+07 2.82E+07 - - - 2.8404 0.8811 221125_WJC_METTL3_EV_vs_WT_F09.07623.07623.3 173 Feb-64 -.MGC[160.03]C[160.03]GC[160.03]SGGC[160.03]GSGC[160.03]GGR.G sp|Q701N2|KRA55_HUMAN 1 1735.5412 0.68 128384 7623 3 1736.544907 579.521 Keratin-associated protein 5-5 OS=Homo sapiens OX=9606 GN=KRTAP5-5 PE=2 SV=2 7.61 1810.2 - 506843 - - - 578.3424 - 0.47 0.523 - 4.3 1 2 0 1.0037 17 0 0 0 1.50E+07 2.19E+07 - - - 2.1855 0.9999 221125_WJC_METTL3_EV_vs_WT_F09.07629.07629.3 0.00357 15/40 R.RQAVDVSPLRR.V "sp|P46782|RS5_HUMAN,tr|M0QZN2|M0QZN2_HUMAN,tr|M0R0F0|M0R0F0_HUMAN,tr|M0R0R2|M0R0R2_HUMAN" 4 1295.7422 0.89 128388 7629 3 1295.74188 432.9213 40S ribosomal protein S5 OS=Homo sapiens OX=9606 GN=RPS5 PE=1 SV=4 11.7 1811 - 1.41E+06 - - - -0.2593 - 2.451 0.408 - 389.2 1 2 0 -0.0003 11 0 0 0 8.03E+07 9.00E+07 - - - 5.6355 1 221125_WJC_METTL3_EV_vs_WT_F09.07639.07639.3 4.57E-05 15/40 R.R[166.11]QAVDVSPLR[166.11]R[166.11].V "sp|P46782|RS5_HUMAN,tr|M0QZN2|M0QZN2_HUMAN,tr|M0R0F0|M0R0F0_HUMAN,tr|M0R0R2|M0R0R2_HUMAN" 4 1325.767 0.89 128394 7639 3 1325.767051 442.9296 40S ribosomal protein S5 OS=Homo sapiens OX=9606 GN=RPS5 PE=1 SV=4 11.7 1812.2 - 2.81E+06 - - - 0.0189 - 2.43 0.503 - 333.2 1 2 0 0 11 0 0 0 8.03E+07 9.02E+07 - - - 6.6703 0.9972 221125_WJC_METTL3_EV_vs_WT_F09.07643.07643.3 0.000806 Nov-48 K.IQDK[136.11]EGIPPDQQR[166.11].L "sp|P62979|RS27A_HUMAN,sp|P0CG48|UBC_HUMAN,sp|P0CG48|UBC_HUMAN,sp|P0CG48|UBC_HUMAN,sp|P0CG48|UBC_HUMAN,sp|P0CG48|UBC_HUMAN,sp|P0CG48|UBC_HUMAN,sp|P0CG48|UBC_HUMAN,sp|P0CG48|UBC_HUMAN,sp|P0CG48|UBC_HUMAN,sp|P0CG47|UBB_HUMAN,sp|P0CG47|UBB_HUMAN,sp|P0CG47|UBB_HUMAN,sp|P62987|RL40_HUMAN,tr|F5H388|F5H388_HUMAN,tr|F5H388|F5H388_HUMAN,tr|F5GYU3|F5GYU3_HUMAN,tr|F5GYU3|F5GYU3_HUMAN,tr|B4DV12|B4DV12_HUMAN,tr|B4DV12|B4DV12_HUMAN,tr|J3QSA3|J3QSA3_HUMAN,tr|Q5PY61|Q5PY61_HUMAN,tr|Q5PY61|Q5PY61_HUMAN,tr|Q5PY61|Q5PY61_HUMAN,tr|F5H2Z3|F5H2Z3_HUMAN,tr|F5H2Z3|F5H2Z3_HUMAN,tr|M0R2S1|M0R2S1_HUMAN,tr|J3QS39|J3QS39_HUMAN,tr|J3QTR3|J3QTR3_HUMAN,tr|Q96C32|Q96C32_HUMAN,tr|Q96C32|Q96C32_HUMAN,tr|Q96C32|Q96C32_HUMAN,tr|Q96C32|Q96C32_HUMAN,tr|M0R1V7|M0R1V7_HUMAN,tr|F5H747|F5H747_HUMAN,tr|F5H747|F5H747_HUMAN,tr|F5GXK7|F5GXK7_HUMAN,tr|F5GXK7|F5GXK7_HUMAN,tr|M0R1M6|M0R1M6_HUMAN,tr|F5H6Q2|F5H6Q2_HUMAN,tr|F5H6Q2|F5H6Q2_HUMAN,tr|F5GZ39|F5GZ39_HUMAN,tr|J3QKN0|J3QKN0_HUMAN,tr|J3QKN0|J3QKN0_HUMAN,tr|F5H265|F5H265_HUMAN,tr|F5H265|F5H265_HUMAN,tr|A0A2R8Y422|A0A2R8Y422_HUMAN" 47 1540.7964 0.9 128396 7643 3 1540.796307 514.6061 Ubiquitin-40S ribosomal protein S27a OS=Homo sapiens OX=9606 GN=RPS27A PE=1 SV=2 4.56 1812.8 - 396461 - - - -0.0863 - 2.034 0.288 - 170.2 1 2 1 -0.0001 13 0 0 0 1.00E+07 1.11E+07 - - - 3.6759 0.976 221125_WJC_METTL3_EV_vs_WT_F09.07644.07644.3 0.00397 Nov-64 K.ASVHTLSGHTNAVATVR.C "sp|O43660|PLRG1_HUMAN,tr|H0YA24|H0YA24_HUMAN" 2 1719.9016 0.95 128397 7644 3 1719.900081 574.3078 Pleiotropic regulator 1 OS=Homo sapiens OX=9606 GN=PLRG1 PE=1 SV=1 9.81 1812.9 - 147004 - - - -0.9006 - 1.502 0.154 - 97 1 2 0 -0.0015 17 0 0 0 4.15E+07 4.37E+07 - - - 1.2842 0.9861 221125_WJC_METTL3_EV_vs_WT_F09.07648.07648.3 0.00445 13/48 L.GGVDQIHIKPGAK.V "sp|P22087|FBRL_HUMAN,tr|M0R299|M0R299_HUMAN,tr|M0R0P1|M0R0P1_HUMAN,tr|M0R1H0|M0R1H0_HUMAN,tr|M0QXL5|M0QXL5_HUMAN,tr|M0R2Q4|M0R2Q4_HUMAN,tr|M0R2B0|M0R2B0_HUMAN,tr|M0R2U2|M0R2U2_HUMAN" 8 1318.7357 0.46 128398 7648 3 1318.735552 440.5859 rRNA 2'-O-methyltransferase fibrillarin OS=Homo sapiens OX=9606 GN=FBL PE=1 SV=2 8.6 1813.5 - 769555 - - - -0.138 - 1.785 0.431 - 245.8 1 1 0 -0.0002 13 0 0 0 2.06E+07 4.47E+07 - - - 4.9161 1 221125_WJC_METTL3_EV_vs_WT_F09.07653.07653.3 6.70E-08 Dec-84 R.GLVHAAGPGQDSGSQAGSPPTR.D sp|Q96ER9|MITOK_HUMAN 1 2045.9879 1.78 128400 7653 3 2045.986967 683.0032 Mitochondrial potassium channel OS=Homo sapiens OX=9606 GN=CCDC51 PE=1 SV=2 6.74 1814.1 - 153154 - - - -0.4458 - 2.833 0.61 - 132.2 1 2 0 -0.0009 22 0 0 0 4.33E+06 2.43E+06 - - - 7.8095 0.9999 221125_WJC_METTL3_EV_vs_WT_F09.07656.07656.3 5.38E-05 15/44 R.TEFAGDKFKEEK.V "sp|O43615|TIM44_HUMAN,tr|M0QXU7|M0QXU7_HUMAN" 2 1427.6933 1.12 128403 7656 3 1427.693218 476.905 Mitochondrial import inner membrane translocase subunit TIM44 OS=Homo sapiens OX=9606 GN=TIMM44 PE=1 SV=2 4.87 1814.3 - 1.81E+06 - - - -0.0294 - 2.826 0.498 - 247.5 1 2 2 0 12 0 0 0 5.87E+07 5.23E+07 - - - 6.9718 0.9911 221125_WJC_METTL3_EV_vs_WT_F09.07663.07663.3 0.00682 Oct-60 K.RINPPSSGGTSSSPIK.A "sp|P14859|PO2F1_HUMAN,tr|A0A0C4DG88|A0A0C4DG88_HUMAN,tr|A0A0A0MT46|A0A0A0MT46_HUMAN" 3 1583.8267 1.71 128406 7663 3 1583.833281 528.9495 "POU domain, class 2, transcription factor 1 OS=Homo sapiens OX=9606 GN=POU2F1 PE=1 SV=2" 11 1815.4 - 314468 - - - 4.1337 - 1.722 0.302 - 87.3 1 2 0 0.0065 16 0 0 0 1.29E+07 7.51E+06 - - - 3.2997 0.9948 221125_WJC_METTL3_EV_vs_WT_F09.07665.07665.3 2.25E-06 Dec-48 L.GGVDQIHIK[136.11]PGAK[136.11].V "sp|P22087|FBRL_HUMAN,tr|M0R299|M0R299_HUMAN,tr|M0R0P1|M0R0P1_HUMAN,tr|M0R1H0|M0R1H0_HUMAN,tr|M0QXL5|M0QXL5_HUMAN,tr|M0R2Q4|M0R2Q4_HUMAN,tr|M0R2B0|M0R2B0_HUMAN,tr|M0R2U2|M0R2U2_HUMAN" 8 1334.7641 0.48 128408 7665 3 1334.764905 445.9287 rRNA 2'-O-methyltransferase fibrillarin OS=Homo sapiens OX=9606 GN=FBL PE=1 SV=2 8.6 1815.7 - 876479 - - - 0.5776 - 2.132 0.476 - 182.1 1 1 0 0.0008 13 0 0 0 2.06E+07 4.31E+07 - - - 5.8993 1 221125_WJC_METTL3_EV_vs_WT_F09.07666.07666.3 2.11E-05 Oct-48 K.DGEQHEDLNEVAK[136.11].L "sp|O95831|AIFM1_HUMAN,tr|A0A6Q8PHJ9|A0A6Q8PHJ9_HUMAN,tr|E9PMA0|E9PMA0_HUMAN,tr|A0A7I2PK44|A0A7I2PK44_HUMAN,tr|A0A6Q8PG15|A0A6Q8PG15_HUMAN,tr|A0A6Q8PFE1|A0A6Q8PFE1_HUMAN,tr|A0A6Q8PHJ4|A0A6Q8PHJ4_HUMAN,tr|A0A6Q8PHC0|A0A6Q8PHC0_HUMAN,tr|A0A6Q8PFM5|A0A6Q8PFM5_HUMAN" 9 1490.6729 1.03 128409 7666 3 1490.670623 497.8982 "Apoptosis-inducing factor 1, mitochondrial OS=Homo sapiens OX=9606 GN=AIFM1 PE=1 SV=1" 4.17 1815.8 - 699346 - - - -1.5047 - 1.893 0.56 - 124 1 2 0 -0.0022 13 0 0 0 3.95E+07 3.85E+07 - - - 6.5131 0.9999 221125_WJC_METTL3_EV_vs_WT_F09.07671.07671.3 1.20E-06 14/44 R.TEFAGDK[136.11]FK[136.11]EEK[136.11].V "sp|O43615|TIM44_HUMAN,tr|M0QXU7|M0QXU7_HUMAN" 2 1451.7359 1.12 128412 7671 3 1451.736898 484.9192 Mitochondrial import inner membrane translocase subunit TIM44 OS=Homo sapiens OX=9606 GN=TIMM44 PE=1 SV=2 4.87 1816.3 - 2.40E+06 - - - 0.715 - 2.86 0.505 - 293.9 1 2 2 0.001 12 0 0 0 5.87E+07 5.23E+07 - - - 7.0827 0.9994 221125_WJC_METTL3_EV_vs_WT_F09.07672.07672.3 1.04E-08 20/64 K.ASVHTLSGHTNAVATVR[166.11].C "sp|O43660|PLRG1_HUMAN,tr|H0YA24|H0YA24_HUMAN" 2 1729.9099 0.72 128413 7672 3 1730.914193 577.6439 Pleiotropic regulator 1 OS=Homo sapiens OX=9606 GN=PLRG1 PE=1 SV=1 9.81 1816.5 - 684530 - - - 580.5464 - 3.03 0.53 - 386.7 1 2 0 1.0043 17 0 0 0 1.32E+07 1.82E+07 - - - 6.9714 0.9997 221125_WJC_METTL3_EV_vs_WT_F09.07678.07678.2 0.000191 Jul-32 K.QGPVSQSATQQPVTADK.Q "sp|Q9BTA9|WAC_HUMAN,tr|A0A7P0T961|A0A7P0T961_HUMAN,tr|A0A0A0MRT2|A0A0A0MRT2_HUMAN,tr|J3QTA0|J3QTA0_HUMAN" 4 1740.8642 1.89 128415 7678 2 1740.865644 871.4394 WW domain-containing adapter protein with coiled-coil OS=Homo sapiens OX=9606 GN=WAC PE=1 SV=3 5.84 1817.3 - 92929.7 - - - 0.8053 - 1.527 0.517 - 100.4 1 2 0 0.0014 17 0 0 0 4.44E+06 2.35E+06 - - - 3.8998 0.9977 221125_WJC_METTL3_EV_vs_WT_F09.07681.07681.2 0.0046 May-32 K.QGPVSQSATQQPVTADK[136.11].Q "sp|Q9BTA9|WAC_HUMAN,tr|A0A7P0T961|A0A7P0T961_HUMAN,tr|A0A0A0MRT2|A0A0A0MRT2_HUMAN,tr|J3QTA0|J3QTA0_HUMAN" 4 1748.8784 1.89 128417 7681 2 1748.882224 875.4465 WW domain-containing adapter protein with coiled-coil OS=Homo sapiens OX=9606 GN=WAC PE=1 SV=3 5.84 1817.6 - 66837.2 - - - 2.1625 - 1.259 0.389 - 29.5 1 2 0 0.0038 17 0 0 0 4.44E+06 2.35E+06 - - - 2.4792 0.9999 221125_WJC_METTL3_EV_vs_WT_F09.07684.07684.4 5.20E-07 17/72 R.VR[166.11]IEGDNENK[136.11]LPR[166.11].E "sp|P51114|FXR1_HUMAN,tr|E7EU85|E7EU85_HUMAN,tr|E9PFF5|E9PFF5_HUMAN,tr|B4DXZ6|B4DXZ6_HUMAN" 4 1566.8472 1.47 128418 7684 4 1566.848638 392.7191 Fragile X mental retardation syndrome-related protein 1 OS=Homo sapiens OX=9606 GN=FXR1 PE=1 SV=3 6.15 1818.1 - 602103 - - - 0.8897 - 2.612 0.523 - 230.1 1 2 2 0.0014 13 0 0 0 7.88E+07 5.36E+07 - - - 4.1338 1 221125_WJC_METTL3_EV_vs_WT_F09.07686.07686.3 1.43E-07 17/60 K.HSGPNSADSANDGFVR.L sp|P52597|HNRPF_HUMAN 1 1629.7132 0.88 128420 7686 3 1629.717364 544.245 Heterogeneous nuclear ribonucleoprotein F OS=Homo sapiens OX=9606 GN=HNRNPF PE=1 SV=3 5.21 1818.2 - 4.87E+06 - - - 2.579 - 3.057 0.66 - 448.7 1 2 0 0.0042 16 0 0 0 5.92E+08 6.70E+08 - - - 8.7644 0.9987 221125_WJC_METTL3_EV_vs_WT_F09.07687.07687.3 1.95E-09 15/48 R.VRIEGDNENKLPR.E "sp|P51114|FXR1_HUMAN,tr|E7EU85|E7EU85_HUMAN,tr|E9PFF5|E9PFF5_HUMAN,tr|B4DXZ6|B4DXZ6_HUMAN" 4 1538.8165 1.62 128421 7687 3 1538.821495 513.9461 Fragile X mental retardation syndrome-related protein 1 OS=Homo sapiens OX=9606 GN=FXR1 PE=1 SV=3 6.15 1818.3 - 669336 - - - 3.2434 - 2.98 0.377 - 403.1 1 2 2 0.005 13 0 0 0 7.24E+07 4.47E+07 - - - 5.7023 0.9999 221125_WJC_METTL3_EV_vs_WT_F09.07688.07688.3 0.000691 Dec-60 K.KAALSASEGEEVPQDK.A "sp|O95831|AIFM1_HUMAN,tr|A0A6Q8PFW2|A0A6Q8PFW2_HUMAN,tr|A0A6Q8PFA7|A0A6Q8PFA7_HUMAN,tr|A0A6Q8PFS4|A0A6Q8PFS4_HUMAN,tr|A0A7I2PK44|A0A7I2PK44_HUMAN,tr|A0A6Q8PF87|A0A6Q8PF87_HUMAN,tr|A0A6Q8PG15|A0A6Q8PG15_HUMAN,tr|A0A6Q8PFE1|A0A6Q8PFE1_HUMAN,tr|A0A6Q8PFQ8|A0A6Q8PFQ8_HUMAN,tr|A0A6Q8PFM5|A0A6Q8PFM5_HUMAN" 10 1657.8159 0.62 128422 7688 3 1657.818802 553.6126 "Apoptosis-inducing factor 1, mitochondrial OS=Homo sapiens OX=9606 GN=AIFM1 PE=1 SV=1" 4.41 1818.5 - 217915 - - - 1.7535 - 2.418 0.459 - 138.3 1 2 0 0.0029 16 0 0 0 8.87E+06 1.44E+07 - - - 5.9221 1 221125_WJC_METTL3_EV_vs_WT_F09.07691.07691.4 2.28E-05 15/96 K.ASVHTLSGHTNAVATVR.C "sp|O43660|PLRG1_HUMAN,tr|H0YA24|H0YA24_HUMAN" 2 1719.9016 1.12 128423 7691 4 1719.902983 430.9827 Pleiotropic regulator 1 OS=Homo sapiens OX=9606 GN=PLRG1 PE=1 SV=1 9.81 1818.9 - 959335 - - - 0.7867 - 2.542 0.502 - 145 1 2 0 0.0014 17 0 0 0 4.86E+07 4.36E+07 - - - 3.919 0.9998 221125_WJC_METTL3_EV_vs_WT_F09.07692.07692.3 2.99E-05 Sep-48 K.DGEQHEDLNEVAK.L "sp|O95831|AIFM1_HUMAN,tr|A0A6Q8PHJ9|A0A6Q8PHJ9_HUMAN,tr|E9PMA0|E9PMA0_HUMAN,tr|A0A7I2PK44|A0A7I2PK44_HUMAN,tr|A0A6Q8PG15|A0A6Q8PG15_HUMAN,tr|A0A6Q8PFE1|A0A6Q8PFE1_HUMAN,tr|A0A6Q8PHJ4|A0A6Q8PHJ4_HUMAN,tr|A0A6Q8PHC0|A0A6Q8PHC0_HUMAN,tr|A0A6Q8PFM5|A0A6Q8PFM5_HUMAN" 9 1482.6587 0.76 128424 7692 3 1482.661966 495.2268 "Apoptosis-inducing factor 1, mitochondrial OS=Homo sapiens OX=9606 GN=AIFM1 PE=1 SV=1" 4.17 1819 - 1.09E+06 - - - 2.2257 - 1.824 0.448 - 59.1 1 2 0 0.0033 13 0 0 0 2.72E+07 3.58E+07 - - - 5.1634 1 221125_WJC_METTL3_EV_vs_WT_F09.07693.07693.3 8.38E-05 15/60 K.K[136.11]AALSASEGEEVPQDK[136.11].A "sp|O95831|AIFM1_HUMAN,tr|A0A6Q8PFW2|A0A6Q8PFW2_HUMAN,tr|A0A6Q8PFA7|A0A6Q8PFA7_HUMAN,tr|A0A6Q8PFS4|A0A6Q8PFS4_HUMAN,tr|A0A7I2PK44|A0A7I2PK44_HUMAN,tr|A0A6Q8PF87|A0A6Q8PF87_HUMAN,tr|A0A6Q8PG15|A0A6Q8PG15_HUMAN,tr|A0A6Q8PFE1|A0A6Q8PFE1_HUMAN,tr|A0A6Q8PFQ8|A0A6Q8PFQ8_HUMAN,tr|A0A6Q8PFM5|A0A6Q8PFM5_HUMAN" 10 1673.8443 0.62 128425 7693 3 1673.847291 558.9554 "Apoptosis-inducing factor 1, mitochondrial OS=Homo sapiens OX=9606 GN=AIFM1 PE=1 SV=1" 4.41 1819.1 - 467566 - - - 1.7899 - 3.049 0.512 - 219.9 1 2 0 0.003 16 0 0 0 8.87E+06 1.44E+07 - - - 7.1079 0.9997 221125_WJC_METTL3_EV_vs_WT_F09.07695.07695.3 0.000763 Nov-64 K.QGPVSQSATQQPVTADK.Q "sp|Q9BTA9|WAC_HUMAN,tr|A0A7P0T961|A0A7P0T961_HUMAN,tr|A0A0A0MRT2|A0A0A0MRT2_HUMAN,tr|J3QTA0|J3QTA0_HUMAN" 4 1740.8642 2.23 128427 7695 3 1740.864413 581.2954 WW domain-containing adapter protein with coiled-coil OS=Homo sapiens OX=9606 GN=WAC PE=1 SV=3 5.84 1819.4 - 232069 - - - 0.0982 - 1.663 0.408 - 124.2 1 2 0 0.0002 17 0 0 0 5.26E+06 2.36E+06 - - - 4.3737 0.9929 221125_WJC_METTL3_EV_vs_WT_F09.07696.07696.3 0.00776 Jul-52 R.DDPYR[166.11]PAK[136.11]PVPTPK[136.11].K "sp|O14730|RIOK3_HUMAN,tr|B4E1Q4|B4E1Q4_HUMAN" 2 1605.8725 0.41 128428 7696 3 1605.875398 536.2981 Serine\threonine-protein kinase RIO3 OS=Homo sapiens OX=9606 GN=RIOK3 PE=1 SV=2 8.5 1819.5 - 195564 - - - 1.7972 - 1.416 0.259 - 40 1 2 0 0.0029 14 0 0 0 2.49E+06 6.04E+06 - - - 2.3512 0.9999 221125_WJC_METTL3_EV_vs_WT_F09.07700.07700.4 4.36E-05 14/96 K.ASVHTLSGHTNAVATVR[166.11].C "sp|O43660|PLRG1_HUMAN,tr|H0YA24|H0YA24_HUMAN" 2 1729.9099 1.22 128430 7700 4 1729.912074 433.4848 Pleiotropic regulator 1 OS=Homo sapiens OX=9606 GN=PLRG1 PE=1 SV=1 9.81 1820 - 1.17E+06 - - - 1.2567 - 2.465 0.42 - 137.4 1 2 0 0.0022 17 0 0 0 3.18E+07 2.61E+07 - - - 3.1943 0.9995 221125_WJC_METTL3_EV_vs_WT_F09.07702.07702.3 5.67E-07 15/48 R.VR[166.11]IEGDNENK[136.11]LPR[166.11].E "sp|P51114|FXR1_HUMAN,tr|E7EU85|E7EU85_HUMAN,tr|E9PFF5|E9PFF5_HUMAN,tr|B4DXZ6|B4DXZ6_HUMAN" 4 1566.8472 1.64 128432 7702 3 1566.849816 523.2897 Fragile X mental retardation syndrome-related protein 1 OS=Homo sapiens OX=9606 GN=FXR1 PE=1 SV=3 6.15 1820.2 - 759681 - - - 1.6415 - 2.503 0.413 - 386.9 1 2 2 0.0026 13 0 0 0 7.34E+07 4.47E+07 - - - 5.6314 0.9985 221125_WJC_METTL3_EV_vs_WT_F09.07703.07703.3 0.000531 Dec-48 K.ETGYVVERPSTTK.D "sp|Q9NYF8|BCLF1_HUMAN,tr|E9PKI6|E9PKI6_HUMAN,tr|A0A1W2PQ43|A0A1W2PQ43_HUMAN,tr|E9PK91|E9PK91_HUMAN,tr|E9PK09|E9PK09_HUMAN,tr|E9PQN2|E9PQN2_HUMAN" 6 1465.7413 1.99 128433 7703 3 1465.742568 489.5877 Bcl-2-associated transcription factor 1 OS=Homo sapiens OX=9606 GN=BCLAF1 PE=1 SV=2 6.24 1820.3 - 460812 - - - 0.8835 - 1.909 0.249 - 136.8 1 2 0 0.0013 13 0 0 0 1.67E+08 8.39E+07 - - - 3.0688 0.9996 221125_WJC_METTL3_EV_vs_WT_F09.07704.07704.2 1.65E-07 14/22 R.SQYEQLAEQNRK.D "sp|P13645|K1C10_HUMAN,tr|A0A1B0GVI3|A0A1B0GVI3_HUMAN" 2 1492.727 999 128434 7704 2 1492.731299 747.3708 "Keratin, type I cytoskeletal 10 OS=Homo sapiens OX=9606 GN=KRT10 PE=1 SV=6" 5.86 1820.4 - 458400 - - - 2.8666 - 2.66 0.519 - 680.8 1 2 0 0.0043 12 0 0 0 1.46E+09 0.00E+00 - - - 5.4471 0.9268 221125_WJC_METTL3_EV_vs_WT_F09.07709.07709.3 2.04 Jul-64 K.QGPVSQSATQQPVTADK[136.11].Q "sp|Q9BTA9|WAC_HUMAN,tr|A0A7P0T961|A0A7P0T961_HUMAN,tr|A0A0A0MRT2|A0A0A0MRT2_HUMAN,tr|J3QTA0|J3QTA0_HUMAN" 4 1748.8784 2.23 128439 7709 3 1748.879585 583.9668 WW domain-containing adapter protein with coiled-coil OS=Homo sapiens OX=9606 GN=WAC PE=1 SV=3 5.84 1821.1 - 187661 - - - 0.6536 - 1.13 0.16 - 48.7 1 2 0 0.0011 17 0 0 0 5.26E+06 2.36E+06 - - - 0.6323 0.9998 221125_WJC_METTL3_EV_vs_WT_F09.07710.07710.2 6.68E-05 24-Aug K.DGEQHEDLNEVAK.L "sp|O95831|AIFM1_HUMAN,tr|A0A6Q8PHJ9|A0A6Q8PHJ9_HUMAN,tr|E9PMA0|E9PMA0_HUMAN,tr|A0A7I2PK44|A0A7I2PK44_HUMAN,tr|A0A6Q8PG15|A0A6Q8PG15_HUMAN,tr|A0A6Q8PFE1|A0A6Q8PFE1_HUMAN,tr|A0A6Q8PHJ4|A0A6Q8PHJ4_HUMAN,tr|A0A6Q8PHC0|A0A6Q8PHC0_HUMAN,tr|A0A6Q8PFM5|A0A6Q8PFM5_HUMAN" 9 1482.6587 0.79 128440 7710 2 1482.656368 742.3366 "Apoptosis-inducing factor 1, mitochondrial OS=Homo sapiens OX=9606 GN=AIFM1 PE=1 SV=1" 4.17 1821.2 - 84721.1 - - - -1.5499 - 1.831 0.522 - 201.5 1 2 0 -0.0023 13 0 0 0 1.53E+06 1.94E+06 - - - 4.4482 0.9998 221125_WJC_METTL3_EV_vs_WT_F09.07712.07712.2 0.000145 26-Dec K.K[136.11]GPGEVAGTVTGQK[136.11].R "sp|Q86U44|MTA70_HUMAN,tr|F5H6D8|F5H6D8_HUMAN,tr|H0YFV6|H0YFV6_HUMAN,tr|B4DTN4|B4DTN4_HUMAN" 4 1343.738 0.01 128441 7712 2 1343.739368 672.8763 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 8.59 1821.5 - 297402 - - - 1.0337 - 2.704 0.443 - 340 1 2 0 0.0014 14 0 0 0 2.19E+05 2.14E+07 - - - 4.8088 0.9883 221125_WJC_METTL3_EV_vs_WT_F09.07716.07716.2 7.63E-05 18-Nov Q.YEQLAEQNRK.D "sp|P13645|K1C10_HUMAN,tr|A0A1B0GVI3|A0A1B0GVI3_HUMAN" 2 1277.6364 999 128444 7716 2 1277.635632 639.8255 "Keratin, type I cytoskeletal 10 OS=Homo sapiens OX=9606 GN=KRT10 PE=1 SV=6" 6.14 1821.9 - 789180 - - - -0.6121 - 2.075 0.419 - 562.9 1 1 0 -0.0008 10 0 0 0 4.04E+08 0.00E+00 - - - 4.173 0.9925 221125_WJC_METTL3_EV_vs_WT_F09.07742.07742.2 0.000149 20-Nov S.QYEQLAEQNRK.D "sp|P13645|K1C10_HUMAN,tr|A0A1B0GVI3|A0A1B0GVI3_HUMAN" 2 1405.695 999 128461 7742 2 1405.693947 703.8548 "Keratin, type I cytoskeletal 10 OS=Homo sapiens OX=9606 GN=KRT10 PE=1 SV=6" 6.14 1825 - 536502 - - - -0.7434 - 2.13 0.522 - 515.7 1 1 0 -0.001 11 0 0 0 2.55E+07 0.00E+00 - - - 4.9417 0.9603 221125_WJC_METTL3_EV_vs_WT_F09.07754.07754.3 0.000393 14/40 S.QYEQLAEQNRK.D "sp|P13645|K1C10_HUMAN,tr|A0A1B0GVI3|A0A1B0GVI3_HUMAN" 2 1405.695 195.57 128467 7754 3 1405.690118 469.5723 "Keratin, type I cytoskeletal 10 OS=Homo sapiens OX=9606 GN=KRT10 PE=1 SV=6" 6.14 1826.4 - 993433 - - - -3.4673 - 2.01 0.445 - 317.6 1 1 0 -0.0049 11 0 0 0 3.06E+07 1.57E+05 - - - 5.4832 0.997 221125_WJC_METTL3_EV_vs_WT_F09.07776.07776.3 0.00948 Dec-40 R.NTKQEIAEINR.M "sp|P48668|K2C6C_HUMAN,sp|P04259|K2C6B_HUMAN,sp|P02538|K2C6A_HUMAN" 3 1314.6892 37.16 128478 7776 3 1314.687964 439.237 "Keratin, type II cytoskeletal 6C OS=Homo sapiens OX=9606 GN=KRT6C PE=1 SV=3" 6.14 1829.2 - 1.21E+06 - - - -0.9234 - 2.068 0.271 - 237.3 1 2 1 -0.0012 11 0 0 0 6.44E+07 1.73E+06 - - - 3.6251 0.9997 221125_WJC_METTL3_EV_vs_WT_F09.07777.07777.3 1.37E-06 15/52 K.K[136.11]GPGEVAGTVTGQK[136.11].R "sp|Q86U44|MTA70_HUMAN,tr|F5H6D8|F5H6D8_HUMAN,tr|H0YFV6|H0YFV6_HUMAN,tr|B4DTN4|B4DTN4_HUMAN" 4 1343.738 0.02 128479 7777 3 1343.732627 448.9199 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 8.59 1829.3 - 1.10E+06 - - - -3.9829 - 2.707 0.458 - 275.7 1 2 0 -0.0054 14 0 0 0 1.06E+06 5.27E+07 - - - 6.2912 0.9998 221125_WJC_METTL3_EV_vs_WT_F09.07781.07781.3 2.34E-06 17/60 R.DGGGRGPDELEGPDSK.L sp|P48634|PRC2A_HUMAN 1 1584.7016 1.13 128481 7781 3 1584.697092 529.2411 Protein PRRC2A OS=Homo sapiens OX=9606 GN=PRRC2A PE=1 SV=3 4.11 1829.8 - 1.22E+06 - - - -2.8403 - 2.94 0.577 - 317.7 1 2 1 -0.0045 16 0 0 0 5.51E+07 4.88E+07 - - - 7.7388 0.9999 221125_WJC_METTL3_EV_vs_WT_F09.07785.07785.3 0.000119 Aug-48 K.ETGYVVER[166.11]PSTTK[136.11].D "sp|Q9NYF8|BCLF1_HUMAN,tr|E9PKI6|E9PKI6_HUMAN,tr|A0A1W2PQ43|A0A1W2PQ43_HUMAN,tr|E9PK91|E9PK91_HUMAN,tr|E9PK09|E9PK09_HUMAN,tr|E9PQN2|E9PQN2_HUMAN" 6 1483.7637 2.05 128482 7785 3 1483.763186 495.5952 Bcl-2-associated transcription factor 1 OS=Homo sapiens OX=9606 GN=BCLAF1 PE=1 SV=2 6.24 1830.5 - 1.67E+06 - - - -0.3754 - 1.754 0.442 - 65.2 1 2 0 -0.0006 13 0 0 0 1.74E+08 8.46E+07 - - - 4.9912 0.9833 221125_WJC_METTL3_EV_vs_WT_F09.07787.07787.2 0.000435 20-Dec R.NTKQEIAEINR.M "sp|P48668|K2C6C_HUMAN,sp|P04259|K2C6B_HUMAN,sp|P02538|K2C6A_HUMAN" 3 1314.6892 999 128483 7787 2 1314.683489 658.3519 "Keratin, type II cytoskeletal 6C OS=Homo sapiens OX=9606 GN=KRT6C PE=1 SV=3" 6.14 1830.7 - 383410 - - - -4.3273 - 2.177 0.489 - 549 1 2 1 -0.0057 11 0 0 0 9.12E+06 0.00E+00 - - - 4.7555 1 221125_WJC_METTL3_EV_vs_WT_F09.07797.07797.3 2.28E-06 15/60 K.LLETTDRPDGHQNNLR.S "sp|Q14974|IMB1_HUMAN,tr|J3KTM9|J3KTM9_HUMAN" 2 1877.9344 1.38 128488 7797 3 1877.933475 626.9854 Importin subunit beta-1 OS=Homo sapiens OX=9606 GN=KPNB1 PE=1 SV=2 5.38 1831.9 - 514110 - - - -0.4856 - 2.992 0.565 - 279.6 1 2 0 -0.0009 16 0 0 0 4.85E+07 3.50E+07 - - - 7.651 1 221125_WJC_METTL3_EV_vs_WT_F09.07799.07799.3 1.56E-07 13/60 K.LLETTDR[166.11]PDGHQNNLR[166.11].S "sp|Q14974|IMB1_HUMAN,tr|J3KTM9|J3KTM9_HUMAN" 2 1897.9509 1.38 128489 7799 3 1897.946366 633.6576 Importin subunit beta-1 OS=Homo sapiens OX=9606 GN=KPNB1 PE=1 SV=2 5.38 1832.2 - 589899 - - - -2.4031 - 2.577 0.58 - 168.6 1 2 0 -0.0046 16 0 0 0 4.85E+07 3.50E+07 - - - 7.4341 0.9998 221125_WJC_METTL3_EV_vs_WT_F09.07801.07801.2 0.000624 24-Dec K.ETGYVVERPSTTK.D "sp|Q9NYF8|BCLF1_HUMAN,tr|E9PKI6|E9PKI6_HUMAN,tr|A0A1W2PQ43|A0A1W2PQ43_HUMAN,tr|E9PK91|E9PK91_HUMAN,tr|E9PK09|E9PK09_HUMAN,tr|E9PQN2|E9PQN2_HUMAN" 6 1465.7413 3.3 128491 7801 2 1465.738909 733.8779 Bcl-2-associated transcription factor 1 OS=Homo sapiens OX=9606 GN=BCLAF1 PE=1 SV=2 6.24 1832.4 - 220657 - - - -1.6128 - 2.208 0.517 - 507.2 1 2 0 -0.0024 13 0 0 0 9.83E+06 2.97E+06 - - - 4.8917 0.9918 221125_WJC_METTL3_EV_vs_WT_F09.07808.07808.4 0.0494 9/108 K.ALVSGKPAESSAVAATEKK.A sp|O95182|NDUA7_HUMAN 1 1843.0051 2.16 128494 7808 4 1843.002041 461.7585 NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 7 OS=Homo sapiens OX=9606 GN=NDUFA7 PE=1 SV=3 8.54 1833.3 - 318989 - - - -1.6554 - 1.49 0.222 - 44.3 1 2 0 -0.0031 19 0 0 0 1.47E+07 6.80E+06 - - - 1.2923 1 221125_WJC_METTL3_EV_vs_WT_F09.07809.07809.3 0.00112 16/60 R.HSAAATALPLSHGAAR.K sp|O75420|GGYF1_HUMAN 1 1529.8063 0.29 128495 7809 3 1529.807373 510.9427 GRB10-interacting GYF protein 1 OS=Homo sapiens OX=9606 GN=GIGYF1 PE=1 SV=2 9.76 1833.5 - 501381 - - - 0.719 - 3.046 0.497 - 405.8 1 2 0 0.0011 16 0 0 0 1.14E+07 3.90E+07 - - - 6.9387 0.9992 221125_WJC_METTL3_EV_vs_WT_F09.07812.07812.3 0.0114 Sep-72 K.ALVSGKPAESSAVAATEKK.A sp|O95182|NDUA7_HUMAN 1 1843.0051 2.35 128498 7812 3 1843.008379 615.3423 NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 7 OS=Homo sapiens OX=9606 GN=NDUFA7 PE=1 SV=3 8.54 1833.9 - 253855 - - - 1.7835 - 1.697 0.358 - 69.2 1 2 0 0.0033 19 0 0 0 2.95E+06 1.26E+06 - - - 3.8297 1 221125_WJC_METTL3_EV_vs_WT_F09.07815.07815.3 1.08E-05 13/44 R.SQYEQLAEQNRK.D "sp|P13645|K1C10_HUMAN,tr|A0A1B0GVI3|A0A1B0GVI3_HUMAN" 2 1492.727 999 128500 7815 3 1492.7275 498.5829 "Keratin, type I cytoskeletal 10 OS=Homo sapiens OX=9606 GN=KRT10 PE=1 SV=6" 5.86 1834.2 - 8.87E+07 - - - 0.3216 - 2.756 0.553 - 327 1 2 0 0.0005 12 0 0 0 2.07E+10 0.00E+00 - - - 7.5153 0.9995 221125_WJC_METTL3_EV_vs_WT_F09.07817.07817.3 0.00243 Oct-60 R.DGGGR[166.11]GPDELEGPDSK[136.11].L sp|P48634|PRC2A_HUMAN 1 1602.7241 1.15 128501 7817 3 1602.722804 535.2486 Protein PRRC2A OS=Homo sapiens OX=9606 GN=PRRC2A PE=1 SV=3 4.11 1834.4 - 1.95E+06 - - - -0.7855 - 1.857 0.442 - 91.9 1 2 1 -0.0013 16 0 0 0 5.63E+07 4.90E+07 - - - 5.0557 0.9925 221125_WJC_METTL3_EV_vs_WT_F09.07819.07819.3 0.049 Sep-48 K.QDAQSLHGDIPQK[136.11].Q sp|Q9NR30|DDX21_HUMAN 1 1443.7198 0.96 128503 7819 3 1443.715628 482.2472 Nucleolar RNA helicase 2 OS=Homo sapiens OX=9606 GN=DDX21 PE=1 SV=5 5.21 1834.6 - 1.14E+06 - - - -2.8593 - 1.578 0.267 - 66.7 1 2 0 -0.0041 13 0 0 0 3.81E+07 3.95E+07 - - - 2.7524 0.9997 221125_WJC_METTL3_EV_vs_WT_F09.07825.07825.2 3.84E-05 24-Jun K.ETGYVVER[166.11]PSTTK[136.11].D "sp|Q9NYF8|BCLF1_HUMAN,tr|E9PKI6|E9PKI6_HUMAN,tr|A0A1W2PQ43|A0A1W2PQ43_HUMAN,tr|E9PK91|E9PK91_HUMAN,tr|E9PK09|E9PK09_HUMAN,tr|E9PQN2|E9PQN2_HUMAN" 6 1483.7637 3.24 128509 7825 2 1483.762149 742.8891 Bcl-2-associated transcription factor 1 OS=Homo sapiens OX=9606 GN=BCLAF1 PE=1 SV=2 6.24 1835.4 - 123890 - - - -1.0743 - 1.409 0.508 - 112.5 1 2 0 -0.0016 13 0 0 0 9.65E+06 2.97E+06 - - - 3.6726 0.999 221125_WJC_METTL3_EV_vs_WT_F09.07831.07831.3 0.0185 Sep-32 R.EYTINIHKR.L "sp|P62899|RL31_HUMAN,tr|B7Z4C8|B7Z4C8_HUMAN,tr|B7Z4E3|B7Z4E3_HUMAN,tr|B8ZZK4|B8ZZK4_HUMAN,tr|H7C2W9|H7C2W9_HUMAN,tr|C9JU56|C9JU56_HUMAN" 6 1172.6302 1.39 128513 7831 3 1172.630107 391.884 60S ribosomal protein L31 OS=Homo sapiens OX=9606 GN=RPL31 PE=1 SV=1 8.69 1836.2 - 712971 - - - -0.0844 - 1.658 0.29 - 153.9 1 2 0 -0.0001 9 0 0 0 2.72E+07 1.97E+07 - - - 3.297 0.9997 221125_WJC_METTL3_EV_vs_WT_F09.07833.07833.3 0.000283 14/56 K.EGEDPNKAEELPSEK.N sp|Q969S3|ZN622_HUMAN 1 1670.7635 1.57 128515 7833 3 1670.763993 557.9285 Zinc finger protein 622 OS=Homo sapiens OX=9606 GN=ZNF622 PE=1 SV=1 4.14 1836.4 - 630495 - - - 0.2801 - 2.04 0.472 - 214.4 1 2 1 0.0005 15 0 0 0 1.73E+07 1.10E+07 - - - 5.6625 0.9998 221125_WJC_METTL3_EV_vs_WT_F09.07834.07834.3 0.000816 Dec-44 K.K[136.11]LDAQVQELHAK[136.11].V sp|P35580|MYH10_HUMAN 1 1394.7853 0.98 128516 7834 3 1394.785808 465.9357 Myosin-10 OS=Homo sapiens OX=9606 GN=MYH10 PE=1 SV=3 6.75 1836.6 - 354956 - - - 0.39 - 2.136 0.346 - 186.8 1 2 0 0.0005 12 0 0 0 1.34E+07 1.36E+07 - - - 4.5011 0.9993 221125_WJC_METTL3_EV_vs_WT_F09.07835.07835.2 0.00136 20-Aug R.ADTQTYQPYNK.D sp|P84090|ERH_HUMAN 1 1327.6044 2.67 128517 7835 2 1327.606771 664.8095 Enhancer of rudimentary homolog OS=Homo sapiens OX=9606 GN=ERH PE=1 SV=1 5.88 1836.7 - 308546 - - - 1.752 - 1.675 0.394 - 187.8 1 2 0 0.0023 11 0 0 0 1.87E+07 7.00E+06 - - - 3.3458 0.9997 221125_WJC_METTL3_EV_vs_WT_F09.07838.07838.2 0.000187 20-Aug R.ADTQTYQPYNK[136.11].D sp|P84090|ERH_HUMAN 1 1335.6186 2.67 128520 7838 2 1335.617175 668.8166 Enhancer of rudimentary homolog OS=Homo sapiens OX=9606 GN=ERH PE=1 SV=1 5.88 1837.1 - 147964 - - - -1.1006 - 1.736 0.465 - 219.7 1 2 0 -0.0015 11 0 0 0 1.87E+07 7.00E+06 - - - 3.9672 0.9996 221125_WJC_METTL3_EV_vs_WT_F09.07842.07842.3 0.00514 Oct-44 K.KLDAQVQELHAK.V sp|P35580|MYH10_HUMAN 1 1378.7569 0.98 128522 7842 3 1378.756033 460.5929 Myosin-10 OS=Homo sapiens OX=9606 GN=MYH10 PE=1 SV=3 6.75 1837.6 - 559781 - - - -0.6027 - 2.069 0.317 - 194.3 1 2 0 -0.0008 12 0 0 0 1.34E+07 1.36E+07 - - - 4.0893 0.9995 221125_WJC_METTL3_EV_vs_WT_F09.07843.07843.3 0.000598 Aug-48 R.YDERPGPSPLPHR.D sp|P08621|RU17_HUMAN 1 1519.7532 2.55 128523 7843 3 1519.752654 507.5917 U1 small nuclear ribonucleoprotein 70 kDa OS=Homo sapiens OX=9606 GN=SNRNP70 PE=1 SV=2 6.75 1837.7 - 445711 - - - -0.3428 - 1.699 0.339 - 72.4 1 2 0 -0.0005 13 0 0 0 3.03E+07 1.19E+07 - - - 3.7565 0.9993 221125_WJC_METTL3_EV_vs_WT_F09.07844.07844.3 0.0009 Oct-56 K.EGEDPNK[136.11]AEELPSEK[136.11].N sp|Q969S3|ZN622_HUMAN 1 1686.7919 1.59 128524 7844 3 1686.790348 563.2713 Zinc finger protein 622 OS=Homo sapiens OX=9606 GN=ZNF622 PE=1 SV=1 4.14 1837.8 - 417662 - - - -0.9349 - 1.752 0.431 - 95.9 1 2 1 -0.0016 15 0 0 0 1.73E+07 1.09E+07 - - - 4.808 0.968 221125_WJC_METTL3_EV_vs_WT_F09.07854.07854.3 0.000286 Sep-56 L.LETTDRPDGHQNNLR.S "sp|Q14974|IMB1_HUMAN,tr|J3KTM9|J3KTM9_HUMAN" 2 1764.8503 1.2 128530 7854 3 1764.854287 589.2907 Importin subunit beta-1 OS=Homo sapiens OX=9606 GN=KPNB1 PE=1 SV=2 5.38 1839.1 - 134208 - - - 2.2461 - 1.938 0.415 - 55.1 1 1 0 0.004 15 0 0 0 3.35E+06 2.78E+06 - - - 4.8922 0.9999 221125_WJC_METTL3_EV_vs_WT_F09.07859.07859.3 0.000112 Aug-64 R.LNQSDSIEDPNSPAGRR.H sp|Q86VS8|HOOK3_HUMAN 1 1854.882 19.83 128532 7859 3 1854.882926 619.3013 Protein Hook homolog 3 OS=Homo sapiens OX=9606 GN=HOOK3 PE=1 SV=2 4.56 1839.8 - 152479 - - - 0.4901 - 1.685 0.486 - 44.6 1 2 0 0.0009 17 0 0 0 4.17E+06 2.10E+05 - - - 5.2763 1 221125_WJC_METTL3_EV_vs_WT_F09.07864.07864.3 0.0049 17/52 K.LHISHDNIGGPEGK.R sp|P20719|HXA5_HUMAN 1 1472.7372 0.56 128534 7864 3 1472.738318 491.9197 Homeobox protein Hox-A5 OS=Homo sapiens OX=9606 GN=HOXA5 PE=1 SV=2 5.99 1840.5 - 714168 - - - 0.7652 - 3.132 0.462 - 399 1 2 0 0.0011 14 0 0 0 2.69E+07 4.84E+07 - - - 6.7246 0.9998 221125_WJC_METTL3_EV_vs_WT_F09.07874.07874.3 1.30E-06 Nov-60 R.LLSDATVEK[136.11]DESHAGK[136.11].V sp|Q14320|FA50A_HUMAN 1 1714.8708 0.71 128539 7874 3 1714.872905 572.6309 Protein FAM50A OS=Homo sapiens OX=9606 GN=FAM50A PE=1 SV=2 4.75 1841.7 - 187730 - - - 1.2018 - 1.99 0.538 - 112.1 1 2 1 0.0021 16 0 0 0 4.91E+06 6.93E+06 - - - 6.3033 0.9983 221125_WJC_METTL3_EV_vs_WT_F09.07880.07880.4 0.00545 Nov-72 R.YDER[166.11]PGPSPLPHR[166.11].D sp|P08621|RU17_HUMAN 1 1539.7697 1.35 128541 7880 4 1539.773807 385.9497 U1 small nuclear ribonucleoprotein 70 kDa OS=Homo sapiens OX=9606 GN=SNRNP70 PE=1 SV=2 6.75 1842.7 - 499795 - - - 2.6575 - 1.557 0.323 - 70.2 1 2 0 0.0041 13 0 0 0 3.07E+07 2.27E+07 - - - 2.2004 0.9998 221125_WJC_METTL3_EV_vs_WT_F09.07884.07884.3 2.27E-07 15/52 K.TTSSTDGPK[136.11]FPGDK[136.11].S "sp|Q9NZN8|CNOT2_HUMAN,tr|F8VRS8|F8VRS8_HUMAN,tr|F8VUB4|F8VUB4_HUMAN,tr|H0YH84|H0YH84_HUMAN,tr|F8VV52|F8VV52_HUMAN,tr|F8W145|F8W145_HUMAN" 6 1452.7067 1.55 128543 7884 3 1452.708365 485.2429 CCR4-NOT transcription complex subunit 2 OS=Homo sapiens OX=9606 GN=CNOT2 PE=1 SV=1 5.63 1843.1 - 290124 - - - 1.12 - 2.36 0.491 - 273.7 1 2 1 0.0016 14 0 0 0 2.32E+07 1.49E+07 - - - 6.2956 0.9998 221125_WJC_METTL3_EV_vs_WT_F09.07886.07886.4 9.80E-07 16/90 R.LLSDATVEK[136.11]DESHAGK[136.11].V sp|Q14320|FA50A_HUMAN 1 1714.8708 0.52 128545 7886 4 1714.873974 429.725 Protein FAM50A OS=Homo sapiens OX=9606 GN=FAM50A PE=1 SV=2 4.75 1843.4 - 503761 - - - 1.8252 - 2.557 0.514 - 114.5 1 2 1 0.0031 16 0 0 0 6.58E+06 1.26E+07 - - - 4.0297 0.9995 221125_WJC_METTL3_EV_vs_WT_F09.07894.07894.3 0.000119 Oct-60 R.GQDGHGDQGNAFAGVK.G sp|Q5T749|KPRP_HUMAN 1 1556.6968 23.65 128548 7894 3 1556.701402 519.9062 Keratinocyte proline-rich protein OS=Homo sapiens OX=9606 GN=KPRP PE=1 SV=1 5.21 1844.6 - 534538 - - - 2.9678 - 1.678 0.462 - 81 1 2 0 0.0046 16 0 0 0 2.49E+07 1.05E+06 - - - 5.0177 0.9996 221125_WJC_METTL3_EV_vs_WT_F09.07895.07895.3 6.58E-05 Aug-60 R.K[136.11]ADTTTPTTSAITASR[166.11].S sp|Q15059|BRD3_HUMAN 1 1638.8543 0.59 128549 7895 3 1638.858409 547.2921 Bromodomain-containing protein 3 OS=Homo sapiens OX=9606 GN=BRD3 PE=1 SV=1 8.75 1844.7 - 202580 - - - 2.4773 - 1.822 0.426 - 86.4 1 2 0 0.0041 16 0 0 0 5.02E+06 8.52E+06 - - - 4.8277 0.9985 221125_WJC_METTL3_EV_vs_WT_F09.07906.07906.3 3.29E-05 Sep-60 R.LLSDATVEKDESHAGK.V sp|Q14320|FA50A_HUMAN 1 1698.8424 0.71 128555 7906 3 1698.846959 567.2881 Protein FAM50A OS=Homo sapiens OX=9606 GN=FAM50A PE=1 SV=2 4.75 1846.4 - 172557 - - - 2.6577 - 1.81 0.453 - 72.9 1 2 1 0.0045 16 0 0 0 4.91E+06 6.93E+06 - - - 5.1116 0.9239 221125_WJC_METTL3_EV_vs_WT_F09.07915.07915.4 0.00706 Oct-84 K.LKETGYVVERPSTTK.D "sp|Q9NYF8|BCLF1_HUMAN,tr|E9PKI6|E9PKI6_HUMAN,tr|A0A1W2PQ43|A0A1W2PQ43_HUMAN,tr|E9PK91|E9PK91_HUMAN,tr|E9PK09|E9PK09_HUMAN,tr|E9PQN2|E9PQN2_HUMAN" 6 1706.9203 1.97 128560 7915 4 1706.927867 427.7374 Bcl-2-associated transcription factor 1 OS=Homo sapiens OX=9606 GN=BCLAF1 PE=1 SV=2 8.5 1847.7 - 1.36E+06 - - - 4.4331 - 1.784 0.262 - 35.3 1 2 1 0.0076 15 0 0 0 1.18E+10 6.01E+09 - - - 1.7115 0.9928 221125_WJC_METTL3_EV_vs_WT_F09.07917.07917.3 0.000776 Oct-36 K.RLEIEHSVPK.K sp|Q9NZI8|IF2B1_HUMAN 1 1206.6721 1.63 128562 7917 3 1206.675947 403.2313 Insulin-like growth factor 2 mRNA-binding protein 1 OS=Homo sapiens OX=9606 GN=IGF2BP1 PE=1 SV=2 6.76 1848 - 618353 - - - 3.2121 - 1.691 0.26 - 174 1 2 0 0.0039 10 0 0 0 4.81E+07 2.95E+07 - - - 2.9718 0.9996 221125_WJC_METTL3_EV_vs_WT_F09.07923.07923.3 0.000714 18/56 K.LKETGYVVERPSTTK.D "sp|Q9NYF8|BCLF1_HUMAN,tr|E9PKI6|E9PKI6_HUMAN,tr|A0A1W2PQ43|A0A1W2PQ43_HUMAN,tr|E9PK91|E9PK91_HUMAN,tr|E9PK09|E9PK09_HUMAN,tr|E9PQN2|E9PQN2_HUMAN" 6 1706.9203 2.03 128565 7923 3 1706.926019 569.9807 Bcl-2-associated transcription factor 1 OS=Homo sapiens OX=9606 GN=BCLAF1 PE=1 SV=2 8.5 1848.9 - 809003 - - - 3.3505 - 3.037 0.538 - 262.6 1 2 1 0.0057 15 0 0 0 8.67E+09 4.28E+09 - - - 7.4353 0.9956 221125_WJC_METTL3_EV_vs_WT_F09.07925.07925.3 2.63E-05 Aug-64 R.PGTPSDHQSQEASQFER.K "sp|Q6Y7W6|GGYF2_HUMAN,tr|A0A7I2V3H7|A0A7I2V3H7_HUMAN,tr|I1E4Y6|I1E4Y6_HUMAN,tr|A0A7I2V516|A0A7I2V516_HUMAN,tr|A0A7I2V3H0|A0A7I2V3H0_HUMAN,tr|C9JHW1|C9JHW1_HUMAN,tr|A0A7I2V361|A0A7I2V361_HUMAN,tr|E7ESB6|E7ESB6_HUMAN" 8 1899.8347 5.92 128567 7925 3 1899.83738 634.2855 GRB10-interacting GYF protein 2 OS=Homo sapiens OX=9606 GN=GIGYF2 PE=1 SV=1 4.65 1849.1 - 120009 - - - 1.3933 - 1.989 0.554 - 70.5 1 1 0 0.0026 17 0 0 0 2.16E+06 3.65E+05 - - - 6.453 0.9997 221125_WJC_METTL3_EV_vs_WT_F09.07930.07930.3 2.81E-05 19/56 K.LK[136.11]ETGYVVER[166.11]PSTTK[136.11].D "sp|Q9NYF8|BCLF1_HUMAN,tr|E9PKI6|E9PKI6_HUMAN,tr|A0A1W2PQ43|A0A1W2PQ43_HUMAN,tr|E9PK91|E9PK91_HUMAN,tr|E9PK09|E9PK09_HUMAN,tr|E9PQN2|E9PQN2_HUMAN" 6 1732.957 2.03 128570 7930 3 1732.962413 578.6596 Bcl-2-associated transcription factor 1 OS=Homo sapiens OX=9606 GN=BCLAF1 PE=1 SV=2 8.5 1849.8 - 721716 - - - 3.1409 - 3.384 0.541 - 292.6 1 2 1 0.0054 15 0 0 0 8.67E+09 4.28E+09 - - - 7.7511 0.9996 221125_WJC_METTL3_EV_vs_WT_F09.07931.07931.2 3.09E-06 28-Jul K.QQGASGEVYC[160.03]PSGEK.C sp|Q7Z5L9|I2BP2_HUMAN 1 1595.6886 2.27 128571 7931 2 1595.693073 798.8516 Interferon regulatory factor 2-binding protein 2 OS=Homo sapiens OX=9606 GN=IRF2BP2 PE=1 SV=2 4.53 1849.9 - 63713.5 - - - 2.812 - 1.702 0.65 - 121.8 1 2 0 0.0045 15 0 0 0 3.07E+06 1.35E+06 - - - 5.148 0.9996 221125_WJC_METTL3_EV_vs_WT_F09.07937.07937.3 0.000101 Dec-56 R.AAHSEGNTTAGLDMR[166.11].E sp|P78371|TCPB_HUMAN 1 1539.6975 0.44 128575 7937 3 1539.702062 514.2398 T-complex protein 1 subunit beta OS=Homo sapiens OX=9606 GN=CCT2 PE=1 SV=4 5.32 1850.8 - 484565 - - - 2.9473 - 1.928 0.442 - 153.1 1 2 0 0.0045 15 0 0 0 5.41E+06 1.24E+07 - - - 5.1796 0.7809 221125_WJC_METTL3_EV_vs_WT_F09.07938.07938.3 0.332 May-60 K.IIK[136.11]DGEQHEDLNEVAK[136.11].L "sp|O95831|AIFM1_HUMAN,tr|A0A6Q8PHJ9|A0A6Q8PHJ9_HUMAN,tr|E9PMA0|E9PMA0_HUMAN,tr|A0A7I2PK44|A0A7I2PK44_HUMAN,tr|A0A6Q8PG15|A0A6Q8PG15_HUMAN,tr|A0A6Q8PFE1|A0A6Q8PFE1_HUMAN,tr|A0A6Q8PHJ4|A0A6Q8PHJ4_HUMAN,tr|A0A6Q8PHC0|A0A6Q8PHC0_HUMAN,tr|A0A6Q8PFM5|A0A6Q8PFM5_HUMAN" 9 1852.9502 0.61 128576 7938 3 1852.95309 618.6573 "Apoptosis-inducing factor 1, mitochondrial OS=Homo sapiens OX=9606 GN=AIFM1 PE=1 SV=1" 4.5 1850.9 - 106793 - - - 1.5829 - 1.128 0.213 - 22.7 3 2 1 0.0029 16 0 0 0 2.36E+06 3.86E+06 - - - 1.0022 0.8418 221125_WJC_METTL3_EV_vs_WT_F09.07939.07939.3 0.357 Sep-72 K.VRQPEGPESSPSPAGAVEK.A sp|A4D1S0|KLRG2_HUMAN 1 1920.9541 1.37 128577 7939 3 1920.960487 641.3253 Killer cell lectin-like receptor subfamily G member 2 OS=Homo sapiens OX=9606 GN=KLRG2 PE=1 SV=3 4.79 1851 - 87732.1 - - - 3.3145 - 1.714 0.184 - 78.7 1 2 1 0.0064 19 0 0 0 2.29E+06 1.67E+06 - - - 1.9135 1 221125_WJC_METTL3_EV_vs_WT_F09.07940.07940.2 4.44E-08 Oct-38 K.GVGGNNGGNGNGGGAFSQAR.S "sp|P08047|SP1_HUMAN,tr|H3BUU5|H3BUU5_HUMAN,tr|H3BVI2|H3BVI2_HUMAN" 3 1746.7782 1.19 128578 7940 2 1746.778636 874.3964 Transcription factor Sp1 OS=Homo sapiens OX=9606 GN=SP1 PE=1 SV=3 9.75 1851.2 - 79158.9 - - - 0.2376 - 2.256 0.703 - 229.4 1 2 0 0.0004 20 0 0 0 3.23E+06 2.71E+06 - - - 6.2335 0.9999 221125_WJC_METTL3_EV_vs_WT_F09.07944.07944.3 2.11E-08 14/44 K.QR[166.11]YPDGIISK[136.11]PK[136.11].N sp|Q86U44|MTA70_HUMAN 1 1426.8143 0 128580 7944 3 1426.817455 476.612 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 9.7 1851.6 - 6.80E+06 - - - 2.2329 - 2.448 0.621 - 305.8 1 2 1 0.0032 12 0 0 0 9.06E+04 1.18E+09 - - - 7.9442 1 221125_WJC_METTL3_EV_vs_WT_F09.07946.07946.3 3.13E-05 Dec-44 K.EDITHSAQHALR.L sp|Q96SI9|STRBP_HUMAN 1 1376.6797 0.72 128582 7946 3 1376.680697 459.9005 Spermatid perinuclear RNA-binding protein OS=Homo sapiens OX=9606 GN=STRBP PE=1 SV=1 6 1851.8 - 383453 - - - 0.7416 - 2.201 0.486 - 225.4 1 2 0 0.001 12 0 0 0 3.91E+07 5.45E+07 - - - 6.1449 1 221125_WJC_METTL3_EV_vs_WT_F09.07948.07948.2 0.000115 13/26 K.K[136.11]GPGEVAGTVTGQK[136.11].R "sp|Q86U44|MTA70_HUMAN,tr|F5H6D8|F5H6D8_HUMAN,tr|H0YFV6|H0YFV6_HUMAN,tr|B4DTN4|B4DTN4_HUMAN" 4 1343.738 0.01 128584 7948 2 1343.737305 672.8763 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 8.59 1852.1 - 209254 - - - -0.5016 - 2.982 0.574 - 385.1 1 2 0 -0.0007 14 0 0 0 1.75E+05 1.75E+07 - - - 6.0222 1 221125_WJC_METTL3_EV_vs_WT_F09.07949.07949.2 9.67E-10 Nov-38 K.GVGGNNGGNGNGGGAFSQAR[166.11].S "sp|P08047|SP1_HUMAN,tr|H3BUU5|H3BUU5_HUMAN,tr|H3BVI2|H3BVI2_HUMAN" 3 1756.7865 1.19 128585 7949 2 1756.786692 879.4005 Transcription factor Sp1 OS=Homo sapiens OX=9606 GN=SP1 PE=1 SV=3 9.75 1852.2 - 67260.1 - - - 0.1144 - 2.651 0.741 - 290.1 1 2 0 0.0002 20 0 0 0 3.23E+06 2.71E+06 - - - 6.9109 1 221125_WJC_METTL3_EV_vs_WT_F09.07952.07952.3 2.69E-07 14/44 K.EDITHSAQHALR[166.11].L sp|Q96SI9|STRBP_HUMAN 1 1386.6879 0.72 128586 7952 3 1386.687447 463.2366 Spermatid perinuclear RNA-binding protein OS=Homo sapiens OX=9606 GN=STRBP PE=1 SV=1 6 1852.7 - 659928 - - - -0.3599 - 2.429 0.566 - 337.4 1 2 0 -0.0005 12 0 0 0 3.91E+07 5.45E+07 - - - 7.3102 0.9999 221125_WJC_METTL3_EV_vs_WT_F09.07953.07953.4 2.34E-05 14/78 R.QAGEVTFADAHR[166.11]PK[136.11].L sp|Q13243|SRSF5_HUMAN 1 1543.7862 1.62 128587 7953 4 1543.788606 386.9538 Serine\arginine-rich splicing factor 5 OS=Homo sapiens OX=9606 GN=SRSF5 PE=1 SV=1 6.75 1852.8 - 214418 - - - 1.552 - 1.982 0.447 - 143.9 1 2 0 0.0024 14 0 0 0 2.21E+07 1.36E+07 - - - 3.365 0.9999 221125_WJC_METTL3_EV_vs_WT_F09.07955.07955.3 6.77E-05 Nov-56 R.AAHSEGNTTAGLDMR.E sp|P78371|TCPB_HUMAN 1 1529.6893 0.43 128589 7955 3 1529.691301 510.9037 T-complex protein 1 subunit beta OS=Homo sapiens OX=9606 GN=CCT2 PE=1 SV=4 5.32 1853 - 270011 - - - 1.3382 - 1.921 0.488 - 137.3 1 2 0 0.002 15 0 0 0 5.24E+06 1.23E+07 - - - 5.6837 0.9964 221125_WJC_METTL3_EV_vs_WT_F09.07957.07957.2 0.00559 28-Aug K.LKETGYVVERPSTTK.D "sp|Q9NYF8|BCLF1_HUMAN,tr|E9PKI6|E9PKI6_HUMAN,tr|A0A1W2PQ43|A0A1W2PQ43_HUMAN,tr|E9PK91|E9PK91_HUMAN,tr|E9PK09|E9PK09_HUMAN,tr|E9PQN2|E9PQN2_HUMAN" 6 1706.9203 2.1 128591 7957 2 1706.920584 854.4674 Bcl-2-associated transcription factor 1 OS=Homo sapiens OX=9606 GN=BCLAF1 PE=1 SV=2 8.5 1853.3 - 73194.6 - - - 0.1664 - 1.853 0.401 - 143.3 1 2 1 0.0003 15 0 0 0 2.68E+08 1.28E+08 - - - 3.5191 0.9967 221125_WJC_METTL3_EV_vs_WT_F09.07962.07962.2 0.125 22-Dec K.QR[166.11]YPDGIISK[136.11]PK[136.11].N sp|Q86U44|MTA70_HUMAN 1 1426.8143 0.001 128594 7962 2 1426.812404 714.4144 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 9.7 1853.9 - 243551 - - - -1.3071 - 2.371 0.364 - 411.1 1 2 1 -0.0019 12 0 0 0 0.00E+00 3.70E+07 - - - 4.0004 1 221125_WJC_METTL3_EV_vs_WT_F09.07963.07963.3 1.71E-09 22/52 R.QAGEVTFADAHRPK.L sp|Q13243|SRSF5_HUMAN 1 1525.7637 1.14 128595 7963 3 1525.766847 509.5952 Serine\arginine-rich splicing factor 5 OS=Homo sapiens OX=9606 GN=SRSF5 PE=1 SV=1 6.75 1854.1 - 423449 - - - 2.0364 - 3.419 0.552 - 675.1 1 2 0 0.0031 14 0 0 0 3.04E+07 2.67E+07 - - - 7.9604 0.9991 221125_WJC_METTL3_EV_vs_WT_F09.07970.07970.3 0.0115 Nov-44 K.KATVNLLGEEKK.S sp|Q00765|REEP5_HUMAN 1 1328.7664 1.04 128600 7970 3 1328.765505 443.9294 Receptor expression-enhancing protein 5 OS=Homo sapiens OX=9606 GN=REEP5 PE=1 SV=3 8.5 1854.9 - 437426 - - - -0.648 - 1.78 0.29 - 193.5 1 2 0 -0.0009 12 0 0 0 1.28E+07 1.23E+07 - - - 3.3713 1 221125_WJC_METTL3_EV_vs_WT_F09.07972.07972.3 2.55E-06 14/56 R.RLQQQQQQQQLAQMK.L "sp|Q6Y7W6|GGYF2_HUMAN,tr|A0A7I2V3H7|A0A7I2V3H7_HUMAN,tr|I1E4Y6|I1E4Y6_HUMAN,tr|A0A7I2V516|A0A7I2V516_HUMAN,tr|A0A7I2V3H0|A0A7I2V3H0_HUMAN,tr|A0A7I2V361|A0A7I2V361_HUMAN" 6 1882.9796 3.45 128601 7972 3 1882.979685 628.6671 GRB10-interacting GYF protein 2 OS=Homo sapiens OX=9606 GN=GIGYF2 PE=1 SV=1 11 1855.1 - 320111 - - - 0.0648 - 2.85 0.428 - 416.8 1 2 0 0.0001 15 0 0 0 6.23E+06 1.81E+06 - - - 6.0446 1 221125_WJC_METTL3_EV_vs_WT_F09.07974.07974.4 3.69E-06 18/78 R.QAGEVTFADAHRPK.L sp|Q13243|SRSF5_HUMAN 1 1525.7637 1.08 128603 7974 4 1525.762531 382.4482 Serine\arginine-rich splicing factor 5 OS=Homo sapiens OX=9606 GN=SRSF5 PE=1 SV=1 6.75 1855.4 - 534629 - - - -0.7924 - 2.147 0.548 - 224.2 1 2 0 -0.0012 14 0 0 0 1.72E+07 1.60E+07 - - - 4.2735 0.9997 221125_WJC_METTL3_EV_vs_WT_F09.07976.07976.3 0.000637 Oct-60 K.C[160.03]VGNFGNSSGEVDTK[136.11]K[136.11].C "sp|Q69YN2|C19L1_HUMAN,tr|A0A286YF56|A0A286YF56_HUMAN" 2 1713.7963 0.19 128605 7976 3 1713.791761 572.2727 CWF19-like protein 1 OS=Homo sapiens OX=9606 GN=CWF19L1 PE=1 SV=2 6.06 1855.6 - 587375 - - - -2.6479 - 1.63 0.48 - 59.7 1 2 0 -0.0045 16 0 0 0 3.49E+06 1.83E+07 - - - 5.1439 0.9999 221125_WJC_METTL3_EV_vs_WT_F09.07977.07977.3 0.000189 Aug-56 R.R[166.11]LQQQQQQQQLAQMK[136.11].L "sp|Q6Y7W6|GGYF2_HUMAN,tr|A0A7I2V3H7|A0A7I2V3H7_HUMAN,tr|I1E4Y6|I1E4Y6_HUMAN,tr|A0A7I2V516|A0A7I2V516_HUMAN,tr|A0A7I2V3H0|A0A7I2V3H0_HUMAN,tr|A0A7I2V361|A0A7I2V361_HUMAN" 6 1901.002 3.39 128606 7977 3 1901.001794 634.6746 GRB10-interacting GYF protein 2 OS=Homo sapiens OX=9606 GN=GIGYF2 PE=1 SV=1 11 1855.8 - 168218 - - - -0.1257 - 1.712 0.443 - 89.6 1 2 0 -0.0002 15 0 0 0 6.03E+06 1.78E+06 - - - 4.8819 0.7806 221125_WJC_METTL3_EV_vs_WT_F09.07980.07980.2 0.561 14-Aug V.VER[166.11]PSTTK[136.11].D "sp|Q9NYF8|BCLF1_HUMAN,tr|E9PKI6|E9PKI6_HUMAN,tr|A0A1W2PQ43|A0A1W2PQ43_HUMAN,tr|E9PK91|E9PK91_HUMAN,tr|E9PK09|E9PK09_HUMAN,tr|E9PQN2|E9PQN2_HUMAN" 6 934.5203 1.94 128607 7980 2 934.51914 468.2674 Bcl-2-associated transcription factor 1 OS=Homo sapiens OX=9606 GN=BCLAF1 PE=1 SV=2 8.72 1856.2 - 1.05E+06 - - - -1.2038 - 1.873 0.057 - 228.9 1 1 0 -0.0011 8 0 0 0 6.18E+08 3.19E+08 - - - 1.3543 0.9997 221125_WJC_METTL3_EV_vs_WT_F09.07981.07981.3 0.00117 Oct-60 K.EVPQDQHLEAPADQSK[136.11].G sp|Q9Y3D9|RT23_HUMAN 1 1798.8577 1.38 128608 7981 3 1798.855439 600.6265 "28S ribosomal protein S23, mitochondrial OS=Homo sapiens OX=9606 GN=MRPS23 PE=1 SV=2" 4.31 1856.4 - 415302 - - - -1.2602 - 2.141 0.352 - 97 1 2 0 -0.0023 16 0 0 0 1.11E+08 8.00E+07 - - - 4.4171 0.9986 221125_WJC_METTL3_EV_vs_WT_F09.07984.07984.3 6.70E-07 16/52 L.KETGYVVERPSTTK.D "sp|Q9NYF8|BCLF1_HUMAN,tr|E9PKI6|E9PKI6_HUMAN,tr|A0A1W2PQ43|A0A1W2PQ43_HUMAN,tr|E9PK91|E9PK91_HUMAN,tr|E9PK09|E9PK09_HUMAN,tr|E9PQN2|E9PQN2_HUMAN" 6 1593.8362 2.28 128609 7984 3 1593.837268 532.286 Bcl-2-associated transcription factor 1 OS=Homo sapiens OX=9606 GN=BCLAF1 PE=1 SV=2 8.5 1856.7 - 403346 - - - 0.6475 - 3.113 0.553 - 314.6 1 1 0 0.001 14 0 0 0 1.44E+08 6.32E+07 - - - 7.723 0.998 221125_WJC_METTL3_EV_vs_WT_F09.07988.07988.2 6.83E-06 28-Dec K.LK[136.11]ETGYVVER[166.11]PSTTK[136.11].D "sp|Q9NYF8|BCLF1_HUMAN,tr|E9PKI6|E9PKI6_HUMAN,tr|A0A1W2PQ43|A0A1W2PQ43_HUMAN,tr|E9PK91|E9PK91_HUMAN,tr|E9PK09|E9PK09_HUMAN,tr|E9PQN2|E9PQN2_HUMAN" 6 1732.957 2.1 128611 7988 2 1732.953837 867.4858 Bcl-2-associated transcription factor 1 OS=Homo sapiens OX=9606 GN=BCLAF1 PE=1 SV=2 8.5 1857.3 - 496690 - - - -1.8079 - 2.425 0.553 - 294.6 1 2 1 -0.0031 15 0 0 0 2.68E+08 1.28E+08 - - - 5.3023 0.9997 221125_WJC_METTL3_EV_vs_WT_F09.07989.07989.3 0.000486 15/56 K.LKETGYVVER[166.11]PSTTK[136.11].D "sp|Q9NYF8|BCLF1_HUMAN,tr|E9PKI6|E9PKI6_HUMAN,tr|A0A1W2PQ43|A0A1W2PQ43_HUMAN,tr|E9PK91|E9PK91_HUMAN,tr|E9PK09|E9PK09_HUMAN,tr|E9PQN2|E9PQN2_HUMAN" 6 1724.9428 - 128612 7989 3 1724.941186 575.9882 Bcl-2-associated transcription factor 1 OS=Homo sapiens OX=9606 GN=BCLAF1 PE=1 SV=2 8.5 1857.4 - 379195 - - - -0.9183 - 2.639 0.399 - 158.3 1 2 1 -0.0016 15 0 0 0 - - - - - 5.5201 0.9921 221125_WJC_METTL3_EV_vs_WT_F09.07991.07991.3 0.00256 Jun-52 K.ETPDKVELSKEEVK.R sp|Q13610|PWP1_HUMAN 1 1629.8461 1.38 128614 7991 3 1629.844815 544.2893 Periodic tryptophan protein 1 homolog OS=Homo sapiens OX=9606 GN=PWP1 PE=1 SV=1 4.59 1857.7 - 157743 - - - -0.8081 - 1.438 0.307 - 19.3 1 2 2 -0.0013 14 0 0 0 2.59E+06 1.88E+06 - - - 2.9277 0.7712 221125_WJC_METTL3_EV_vs_WT_F09.07998.07998.2 0.457 22-May V.SQYQQALEEIER.L "sp|Q14149|MORC3_HUMAN,tr|H0YHQ4|H0YHQ4_HUMAN,tr|H0YIR5|H0YIR5_HUMAN" 3 1492.7158 999 128617 7998 2 1492.715597 747.3652 MORC family CW-type zinc finger protein 3 OS=Homo sapiens OX=9606 GN=MORC3 PE=1 SV=3 4.25 1858.5 - 215048 - - - -0.1273 - 1.154 0.229 - 63.9 1 1 0 -0.0002 12 0 0 0 3.29E+06 0.00E+00 - - - 1.1092 0.9998 221125_WJC_METTL3_EV_vs_WT_F09.08003.08003.3 0.0224 15/36 R.IRYEDEISKR.T sp|Q6KB66|K2C80_HUMAN 1 1307.6834 92.27 128619 8003 3 1307.680442 436.9017 "Keratin, type II cytoskeletal 80 OS=Homo sapiens OX=9606 GN=KRT80 PE=1 SV=2" 6.18 1859.1 - 1.31E+06 - - - -2.2345 - 2.711 0.483 - 423.5 1 2 1 -0.0029 10 0 0 0 3.74E+07 4.05E+05 - - - 6.8368 0.9859 221125_WJC_METTL3_EV_vs_WT_F09.08007.08007.2 0.000518 16-Nov Y.VVERPSTTK.D "sp|Q9NYF8|BCLF1_HUMAN,tr|E9PKI6|E9PKI6_HUMAN,tr|A0A1W2PQ43|A0A1W2PQ43_HUMAN,tr|E9PK91|E9PK91_HUMAN,tr|E9PK09|E9PK09_HUMAN,tr|E9PQN2|E9PQN2_HUMAN" 6 1015.5662 1.57 128621 8007 2 1015.564362 508.7904 Bcl-2-associated transcription factor 1 OS=Homo sapiens OX=9606 GN=BCLAF1 PE=1 SV=2 8.72 1859.5 - 2.73E+06 - - - -1.8187 - 2.256 0.461 - 348.9 1 1 0 -0.0018 9 0 0 0 4.25E+08 2.71E+08 - - - 4.7991 0.9689 221125_WJC_METTL3_EV_vs_WT_F09.08012.08012.2 5.56E-05 16-Dec Y.VVER[166.11]PSTTK[136.11].D "sp|Q9NYF8|BCLF1_HUMAN,tr|E9PKI6|E9PKI6_HUMAN,tr|A0A1W2PQ43|A0A1W2PQ43_HUMAN,tr|E9PK91|E9PK91_HUMAN,tr|E9PK09|E9PK09_HUMAN,tr|E9PQN2|E9PQN2_HUMAN" 6 1033.5887 1.71 128624 8012 2 1033.586646 517.8016 Bcl-2-associated transcription factor 1 OS=Homo sapiens OX=9606 GN=BCLAF1 PE=1 SV=2 8.72 1860.1 - 2.43E+06 - - - -1.9669 - 2.338 0.309 - 515.5 1 1 0 -0.002 9 0 0 0 4.23E+08 2.48E+08 - - - 3.7797 0.9998 221125_WJC_METTL3_EV_vs_WT_F09.08018.08018.3 2.17E-06 14/44 K.QR[166.11]YPDGIISKPK[136.11].N sp|Q86U44|MTA70_HUMAN 1 1418.8001 - 128627 8018 3 1418.797726 473.9406 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 9.7 1860.9 - 569023 - - - -1.6514 - 2.291 0.512 - 308.1 1 2 1 -0.0023 12 0 0 0 - - - - - 6.5455 1 221125_WJC_METTL3_EV_vs_WT_F09.08027.08027.3 9.58E-05 Nov-52 K.VETSDEEIHDLHQR[166.11].L "sp|P07099|HYEP_HUMAN,tr|B1AQP8|B1AQP8_HUMAN" 2 1716.7943 0.001 128631 8027 3 1716.793564 573.272 Epoxide hydrolase 1 OS=Homo sapiens OX=9606 GN=EPHX1 PE=1 SV=1 4.49 1862 - 335917 - - - -0.406 - 2.102 0.507 - 118.4 1 2 0 -0.0007 14 0 0 0 0.00E+00 1.47E+07 - - - 6.1666 0.9999 221125_WJC_METTL3_EV_vs_WT_F09.08034.08034.2 2.92E-08 16/24 K.ETGYVVERPSTTK.D "sp|Q9NYF8|BCLF1_HUMAN,tr|E9PKI6|E9PKI6_HUMAN,tr|A0A1W2PQ43|A0A1W2PQ43_HUMAN,tr|E9PK91|E9PK91_HUMAN,tr|E9PK09|E9PK09_HUMAN,tr|E9PQN2|E9PQN2_HUMAN" 6 1465.7413 5.9 128634 8034 2 1465.741205 733.8779 Bcl-2-associated transcription factor 1 OS=Homo sapiens OX=9606 GN=BCLAF1 PE=1 SV=2 6.24 1862.8 - 482795 - - - -0.0464 - 2.615 0.507 - 904.5 1 2 0 -0.0001 13 0 0 0 2.32E+07 3.93E+06 - - - 5.2528 1 221125_WJC_METTL3_EV_vs_WT_F09.08053.08053.3 2.41E-05 16/48 K.KQPTPQPPVDC[160.03]VK.T sp|P23490|LORI_HUMAN 1 1492.7708 21.12 128638 8053 3 1492.770598 498.5975 Loricrin OS=Homo sapiens OX=9606 GN=LORICRIN PE=1 SV=2 8.2 1865.6 - 1.26E+06 - - - -0.1346 - 2.804 0.483 - 503.3 1 2 0 -0.0002 13 0 0 0 6.30E+07 2.98E+06 - - - 6.7204 1 221125_WJC_METTL3_EV_vs_WT_F09.08068.08068.3 0.000104 17/76 K.MLENTDNSSPSTEHSQGLEK[136.11].Q sp|Q96H79|ZCCHL_HUMAN 1 2210.9841 1.2 128644 8068 3 2210.976468 738.002 Zinc finger CCCH-type antiviral protein 1-like OS=Homo sapiens OX=9606 GN=ZC3HAV1L PE=1 SV=2 4.4 1867.5 - 619516 - - - -3.4546 - 3.238 0.642 - 205.4 1 2 0 -0.0076 20 0 0 0 1.75E+07 1.47E+07 - - - 8.546 0.9992 221125_WJC_METTL3_EV_vs_WT_F09.08071.08071.4 0.00797 13/72 R.YNLHQIQGHSAPR.H sp|O75319|DUS11_HUMAN 1 1519.7644 1.26 128646 8071 4 1519.76215 380.9484 RNA\RNP complex-1-interacting phosphatase OS=Homo sapiens OX=9606 GN=DUSP11 PE=1 SV=2 8.76 1867.8 - 584355 - - - -1.4864 - 1.549 0.319 - 62.9 1 2 0 -0.0023 13 0 0 0 2.06E+07 1.64E+07 - - - 2.1642 1 221125_WJC_METTL3_EV_vs_WT_F09.08076.08076.3 2.20E-06 Dec-48 R.YNLHQIQGHSAPR[166.11].H sp|O75319|DUS11_HUMAN 1 1529.7727 2.08 128648 8076 3 1529.770331 510.9315 RNA\RNP complex-1-interacting phosphatase OS=Homo sapiens OX=9606 GN=DUSP11 PE=1 SV=2 8.76 1868.4 - 481851 - - - -1.5349 - 2.264 0.502 - 156.3 1 2 0 -0.0023 13 0 0 0 2.25E+07 1.08E+07 - - - 6.3516 1 221125_WJC_METTL3_EV_vs_WT_F09.08078.08078.3 7.66E-07 Nov-56 K.LTSSC[160.03]PDLPSQTDKK.C sp|P56962|STX17_HUMAN 1 1675.8087 0.99 128650 8078 3 1675.809576 559.6102 Syntaxin-17 OS=Homo sapiens OX=9606 GN=STX17 PE=1 SV=2 5.95 1868.7 - 634378 - - - 0.5221 - 2.213 0.502 - 124.6 1 2 0 0.0009 15 0 0 0 4.87E+07 4.90E+07 - - - 6.2093 0.9994 221125_WJC_METTL3_EV_vs_WT_F09.08084.08084.4 0.0063 17/78 K.MK[136.11]ETAENYLGHTAK[136.11].N "sp|P38646|GRP75_HUMAN,tr|H0Y8K0|H0Y8K0_HUMAN,tr|A0A7I2V2S7|A0A7I2V2S7_HUMAN,tr|A0A7I2V2G2|A0A7I2V2G2_HUMAN,tr|A0A7I2V3F7|A0A7I2V3F7_HUMAN,tr|A0A7I2YQB2|A0A7I2YQB2_HUMAN,tr|D6RCD7|D6RCD7_HUMAN" 7 1607.7948 0.45 128654 8084 4 1607.790179 402.956 "Stress-70 protein, mitochondrial OS=Homo sapiens OX=9606 GN=HSPA9 PE=1 SV=2" 6.51 1869.5 - 959160 - - - -2.9002 - 2.552 0.464 - 213.5 1 2 1 -0.0047 14 0 0 0 8.40E+07 1.87E+08 - - - 3.6043 0.9997 221125_WJC_METTL3_EV_vs_WT_F09.08085.08085.3 2.15E-08 17/52 K.MK[136.11]ETAENYLGHTAK[136.11].N "sp|P38646|GRP75_HUMAN,tr|H0Y8K0|H0Y8K0_HUMAN,tr|A0A7I2V2S7|A0A7I2V2S7_HUMAN,tr|A0A7I2V2G2|A0A7I2V2G2_HUMAN,tr|A0A7I2V3F7|A0A7I2V3F7_HUMAN,tr|A0A7I2YQB2|A0A7I2YQB2_HUMAN,tr|D6RCD7|D6RCD7_HUMAN" 7 1607.7948 0.36 128655 8085 3 1607.790137 536.9389 "Stress-70 protein, mitochondrial OS=Homo sapiens OX=9606 GN=HSPA9 PE=1 SV=2" 6.51 1869.6 - 1.06E+06 - - - -2.9264 - 2.472 0.553 - 257.7 1 2 1 -0.0047 14 0 0 0 9.63E+07 2.68E+08 - - - 7.1092 1 221125_WJC_METTL3_EV_vs_WT_F09.08088.08088.3 9.40E-08 Dec-56 K.LTSSC[160.03]PDLPSQTDK[136.11]K[136.11].C sp|P56962|STX17_HUMAN 1 1691.8371 0.99 128656 8088 3 1691.836298 564.953 Syntaxin-17 OS=Homo sapiens OX=9606 GN=STX17 PE=1 SV=2 5.95 1870 - 1.00E+06 - - - -0.4746 - 2.599 0.56 - 165.4 1 2 0 -0.0008 15 0 0 0 4.87E+07 4.90E+07 - - - 7.2755 0.9999 221125_WJC_METTL3_EV_vs_WT_F09.08089.08089.4 5.23E-05 15/72 R.YNLHQIQGHSAPR[166.11].H sp|O75319|DUS11_HUMAN 1 1529.7727 1.26 128657 8089 4 1529.769636 383.4504 RNA\RNP complex-1-interacting phosphatase OS=Homo sapiens OX=9606 GN=DUSP11 PE=1 SV=2 8.76 1870.1 - 540924 - - - -1.9892 - 2.244 0.465 - 126.9 1 2 0 -0.003 13 0 0 0 2.06E+07 1.64E+07 - - - 3.5722 0.9999 221125_WJC_METTL3_EV_vs_WT_F09.08092.08092.3 3.05E-07 17/52 K.SINQQSGAHVELQR.N sp|Q96I24|FUBP3_HUMAN 1 1565.791 1.79 128658 8092 3 1565.786799 522.9376 Far upstream element-binding protein 3 OS=Homo sapiens OX=9606 GN=FUBP3 PE=1 SV=2 6.47 1870.5 - 1.07E+06 - - - -2.6938 - 3.141 0.477 - 292.4 1 2 0 -0.0042 14 0 0 0 4.53E+08 2.53E+08 - - - 6.8986 1 221125_WJC_METTL3_EV_vs_WT_F09.08094.08094.3 1.20E-06 16/52 K.SINQQSGAHVELQR[166.11].N sp|Q96I24|FUBP3_HUMAN 1 1575.7993 1.79 128659 8094 3 1575.799472 526.2737 Far upstream element-binding protein 3 OS=Homo sapiens OX=9606 GN=FUBP3 PE=1 SV=2 6.47 1870.7 - 1.05E+06 - - - 0.1174 - 2.71 0.574 - 274.4 1 2 0 0.0002 14 0 0 0 4.53E+08 2.53E+08 - - - 7.5889 0.999 221125_WJC_METTL3_EV_vs_WT_F09.08100.08100.4 1.47E-06 16/78 K.MKETAENYLGHTAK.N "sp|P38646|GRP75_HUMAN,tr|H0Y8K0|H0Y8K0_HUMAN,tr|A0A7I2V2S7|A0A7I2V2S7_HUMAN,tr|A0A7I2V2G2|A0A7I2V2G2_HUMAN,tr|A0A7I2V3F7|A0A7I2V3F7_HUMAN,tr|A0A7I2YQB2|A0A7I2YQB2_HUMAN,tr|D6RCD7|D6RCD7_HUMAN" 7 1591.7664 0.45 128662 8100 4 1591.763351 398.9489 "Stress-70 protein, mitochondrial OS=Homo sapiens OX=9606 GN=HSPA9 PE=1 SV=2" 6.51 1871.4 - 1.62E+06 - - - -1.9419 - 2.404 0.381 - 197.9 1 2 1 -0.0031 14 0 0 0 8.40E+07 1.87E+08 - - - 2.8606 0.9999 221125_WJC_METTL3_EV_vs_WT_F09.08102.08102.3 8.12E-08 17/52 K.MKETAENYLGHTAK.N "sp|P38646|GRP75_HUMAN,tr|H0Y8K0|H0Y8K0_HUMAN,tr|A0A7I2V2S7|A0A7I2V2S7_HUMAN,tr|A0A7I2V2G2|A0A7I2V2G2_HUMAN,tr|A0A7I2V3F7|A0A7I2V3F7_HUMAN,tr|A0A7I2YQB2|A0A7I2YQB2_HUMAN,tr|D6RCD7|D6RCD7_HUMAN" 7 1591.7664 0.37 128664 8102 3 1591.763562 531.5961 "Stress-70 protein, mitochondrial OS=Homo sapiens OX=9606 GN=HSPA9 PE=1 SV=2" 6.51 1871.6 - 1.75E+06 - - - -1.8093 - 2.949 0.569 - 285.6 1 2 1 -0.0029 14 0 0 0 9.59E+07 2.59E+08 - - - 7.757 1 221125_WJC_METTL3_EV_vs_WT_F09.08104.08104.3 8.13E-06 13/72 K.DAQQVEPEGQEKPSPATVR.S "sp|Q9Y520|PRC2C_HUMAN,tr|E7EPN9|E7EPN9_HUMAN,tr|H7C5N8|H7C5N8_HUMAN,tr|A0A2R8Y7F4|A0A2R8Y7F4_HUMAN,tr|A0A2R8YET2|A0A2R8YET2_HUMAN" 5 2065.0076 3.52 128666 8104 3 2065.005709 689.3431 Protein PRRC2C OS=Homo sapiens OX=9606 GN=PRRC2C PE=1 SV=4 4.41 1871.8 - 268554 - - - -0.9215 - 2.807 0.524 - 108.6 1 2 0 -0.0019 19 0 0 0 1.16E+07 3.30E+06 - - - 6.9173 0.9999 221125_WJC_METTL3_EV_vs_WT_F09.08112.08112.3 0.000317 Nov-44 K.K[136.11]K[136.11]PLFITTDSSK[136.11].L sp|Q7LBC6|KDM3B_HUMAN 1 1387.8137 1.15 128669 8112 3 1387.812356 463.6118 Lysine-specific demethylase 3B OS=Homo sapiens OX=9606 GN=KDM3B PE=1 SV=2 9.7 1872.9 - 1.07E+06 - - - -0.9807 - 2.171 0.402 - 248.6 1 2 0 -0.0014 12 0 0 0 2.05E+07 1.78E+07 - - - 5.1702 0.9823 221125_WJC_METTL3_EV_vs_WT_F09.08113.08113.3 0.0398 Jul-48 R.SKVEETTEHLVTK.S "sp|P52732|KIF11_HUMAN,tr|A0A7I2V3A9|A0A7I2V3A9_HUMAN" 2 1499.7831 11.96 128670 8113 3 1499.783807 500.935 Kinesin-like protein KIF11 OS=Homo sapiens OX=9606 GN=KIF11 PE=1 SV=2 5.47 1873.1 - 276664 - - - 0.4461 - 1.491 0.268 - 31 3 2 1 0.0007 13 0 0 0 1.99E+07 1.66E+06 - - - 2.3899 1 221125_WJC_METTL3_EV_vs_WT_F09.08114.08114.3 0.000176 Nov-44 K.KKPLFITTDSSK.L sp|Q7LBC6|KDM3B_HUMAN 1 1363.7711 1.15 128671 8114 3 1363.77199 455.5976 Lysine-specific demethylase 3B OS=Homo sapiens OX=9606 GN=KDM3B PE=1 SV=2 9.7 1873.1 - 1.16E+06 - - - 0.6401 - 2.128 0.526 - 234.8 1 2 0 0.0009 12 0 0 0 2.05E+07 1.78E+07 - - - 6.4974 1 221125_WJC_METTL3_EV_vs_WT_F09.08115.08115.3 1.02E-06 15/44 R.ELEAENYHDIKR.L "sp|Q01082|SPTB2_HUMAN,tr|A0A087WUZ3|A0A087WUZ3_HUMAN,tr|F8W6C1|F8W6C1_HUMAN" 3 1515.7318 1.23 128672 8115 3 1515.730544 506.2512 "Spectrin beta chain, non-erythrocytic 1 OS=Homo sapiens OX=9606 GN=SPTBN1 PE=1 SV=2" 4.83 1873.3 - 415997 - - - -0.8095 - 2.707 0.573 - 402.2 1 2 0 -0.0012 12 0 0 0 9.20E+06 7.47E+06 - - - 7.6884 1 221125_WJC_METTL3_EV_vs_WT_F09.08117.08117.3 4.02E-08 14/60 R.TPGNNLHEVETAQGQR.F "sp|Q8N9N8|EIF1A_HUMAN,tr|E9PLI6|E9PLI6_HUMAN,tr|E9PQD0|E9PQD0_HUMAN,tr|E9PS30|E9PS30_HUMAN,tr|E9PS76|E9PS76_HUMAN" 5 1749.8394 0.32 128674 8117 3 1749.838953 584.2871 Probable RNA-binding protein EIF1AD OS=Homo sapiens OX=9606 GN=EIF1AD PE=1 SV=1 5.37 1873.5 - 313339 - - - -0.2692 - 2.883 0.608 - 264.5 1 2 0 -0.0005 16 0 0 0 3.97E+06 1.24E+07 - - - 8.0353 0.9985 221125_WJC_METTL3_EV_vs_WT_F09.08120.08120.2 1.55E-10 13/26 K.MK[136.11]ETAENYLGHTAK[136.11].N "sp|P38646|GRP75_HUMAN,tr|H0Y8K0|H0Y8K0_HUMAN,tr|A0A7I2V2S7|A0A7I2V2S7_HUMAN,tr|A0A7I2V2G2|A0A7I2V2G2_HUMAN,tr|A0A7I2V3F7|A0A7I2V3F7_HUMAN,tr|A0A7I2YQB2|A0A7I2YQB2_HUMAN,tr|D6RCD7|D6RCD7_HUMAN" 7 1607.7948 0.27 128677 8120 2 1607.792721 804.9047 "Stress-70 protein, mitochondrial OS=Homo sapiens OX=9606 GN=HSPA9 PE=1 SV=2" 6.51 1873.9 - 152140 - - - -1.3192 - 2.665 0.518 - 360.9 1 2 1 -0.0021 14 0 0 0 1.32E+06 4.97E+06 - - - 5.3261 0.9999 221125_WJC_METTL3_EV_vs_WT_F09.08124.08124.3 0.00256 15/60 K.EVPQDQHLEAPADQSK.G sp|Q9Y3D9|RT23_HUMAN 1 1790.8435 1.38 128679 8124 3 1790.841186 597.9551 "28S ribosomal protein S23, mitochondrial OS=Homo sapiens OX=9606 GN=MRPS23 PE=1 SV=2" 4.31 1874.4 - 1.16E+06 - - - -1.2955 - 2.462 0.418 - 212.8 1 2 0 -0.0023 16 0 0 0 1.11E+08 8.00E+07 - - - 5.5114 1 221125_WJC_METTL3_EV_vs_WT_F09.08126.08126.3 0.000169 13/44 R.ELEAENYHDIK[136.11]R[166.11].L "sp|Q01082|SPTB2_HUMAN,tr|A0A087WUZ3|A0A087WUZ3_HUMAN,tr|F8W6C1|F8W6C1_HUMAN" 3 1533.7542 1.43 128681 8126 3 1533.753157 512.2587 "Spectrin beta chain, non-erythrocytic 1 OS=Homo sapiens OX=9606 GN=SPTBN1 PE=1 SV=2" 4.83 1874.6 - 505328 - - - -0.7068 - 2.509 0.458 - 244.5 1 2 0 -0.0011 12 0 0 0 8.87E+06 6.20E+06 - - - 6.1957 1 221125_WJC_METTL3_EV_vs_WT_F09.08127.08127.2 1.26E-07 15/26 K.SINQQSGAHVELQR.N sp|Q96I24|FUBP3_HUMAN 1 1565.791 1.81 128682 8127 2 1565.792698 783.9028 Far upstream element-binding protein 3 OS=Homo sapiens OX=9606 GN=FUBP3 PE=1 SV=2 6.47 1874.7 - 432179 - - - 1.0736 - 3.099 0.605 - 806.4 1 2 0 0.0017 14 0 0 0 1.29E+07 7.12E+06 - - - 6.3474 1 221125_WJC_METTL3_EV_vs_WT_F09.08128.08128.4 3.64E-05 13/66 R.ELEAENYHDIK[136.11]R[166.11].L "sp|Q01082|SPTB2_HUMAN,tr|A0A087WUZ3|A0A087WUZ3_HUMAN,tr|F8W6C1|F8W6C1_HUMAN" 3 1533.7542 3.78 128683 8128 4 1533.752596 384.4458 "Spectrin beta chain, non-erythrocytic 1 OS=Homo sapiens OX=9606 GN=SPTBN1 PE=1 SV=2" 4.83 1874.9 - 425776 - - - -1.0725 - 2.326 0.527 - 184.4 1 2 0 -0.0016 12 0 0 0 1.90E+07 5.03E+06 - - - 4.132 1 221125_WJC_METTL3_EV_vs_WT_F09.08129.08129.2 1.85E-07 13/26 K.SINQQSGAHVELQR[166.11].N sp|Q96I24|FUBP3_HUMAN 1 1575.7993 1.81 128684 8129 2 1575.798494 788.9069 Far upstream element-binding protein 3 OS=Homo sapiens OX=9606 GN=FUBP3 PE=1 SV=2 6.47 1875 - 282043 - - - -0.5032 - 3.023 0.607 - 673.7 1 2 0 -0.0008 14 0 0 0 1.29E+07 7.12E+06 - - - 6.3001 1 221125_WJC_METTL3_EV_vs_WT_F09.08132.08132.3 1.00E-06 15/52 K.K[136.11]GPGEVAGTVTGQK[136.11].R "sp|Q86U44|MTA70_HUMAN,tr|F5H6D8|F5H6D8_HUMAN,tr|H0YFV6|H0YFV6_HUMAN,tr|B4DTN4|B4DTN4_HUMAN" 4 1343.738 0.01 128685 8132 3 1343.737079 448.9199 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 8.59 1875.5 - 1.08E+06 - - - -0.6698 - 2.717 0.491 - 342.7 1 2 0 -0.0009 14 0 0 0 5.41E+05 1.05E+08 - - - 6.6702 1 221125_WJC_METTL3_EV_vs_WT_F09.08137.08137.2 3.91E-06 30-Jul K.TC[160.03]TYEGC[160.03]SETTSQVAK.Q sp|O00287|RFXAP_HUMAN 1 1820.7557 2.06 128690 8137 2 1820.755491 911.3851 Regulatory factor X-associated protein OS=Homo sapiens OX=9606 GN=RFXAP PE=1 SV=1 4.53 1876.1 - 145822 - - - -0.1038 - 1.826 0.718 - 133.3 1 2 0 -0.0002 16 0 0 0 1.61E+06 7.79E+05 - - - 5.8244 0.9949 221125_WJC_METTL3_EV_vs_WT_F09.08141.08141.3 0.00019 Nov-40 K.EK[136.11]DFSPEALK[136.11]K[136.11].A "sp|O15372|EIF3H_HUMAN,tr|B3KS98|B3KS98_HUMAN,tr|A0A087WZK9|A0A087WZK9_HUMAN,tr|E5RGU4|E5RGU4_HUMAN,tr|E5RJT0|E5RJT0_HUMAN" 5 1314.7246 2.83 128692 8141 3 1314.723667 439.2488 Eukaryotic translation initiation factor 3 subunit H OS=Homo sapiens OX=9606 GN=EIF3H PE=1 SV=1 6.28 1876.6 - 1.81E+06 - - - -0.6846 - 2.105 0.231 - 128.7 1 2 1 -0.0009 11 0 0 0 3.84E+08 1.36E+08 - - - 3.2296 1 221125_WJC_METTL3_EV_vs_WT_F09.08142.08142.2 1.06E-05 16/22 L.NQQSGAHVELQR.N sp|Q96I24|FUBP3_HUMAN 1 1365.6749 2.73 128693 8142 2 1365.677143 683.8447 Far upstream element-binding protein 3 OS=Homo sapiens OX=9606 GN=FUBP3 PE=1 SV=2 6.75 1876.7 - 411063 - - - 1.6241 - 3.016 0.593 - 1210.9 1 1 0 0.0022 12 0 0 0 6.13E+06 2.25E+06 - - - 6.3248 0.9991 221125_WJC_METTL3_EV_vs_WT_F09.08146.08146.3 0.0257 Sep-60 R.LQTVHHNADVYQAVSK.R tr|A0A1W2PQ72|A0A1W2PQ72_HUMAN 1 1808.9169 1.55 128695 8146 3 1808.915368 603.9796 Myb_DNA-bind_4 domain-containing protein OS=Homo sapiens OX=9606 GN=LOC100421372 PE=1 SV=1 6.92 1877.3 - 184188 - - - -0.8723 - 1.637 0.323 - 29.1 1 2 0 -0.0016 16 0 0 0 2.74E+06 1.76E+06 - - - 3.4053 0.9838 221125_WJC_METTL3_EV_vs_WT_F09.08147.08147.3 0.0453 Jul-56 K.AIEIDEQQGC[160.03]KEQER.L sp|Q9NVK5|FGOP2_HUMAN 1 1831.837 20.71 128696 8147 3 1831.838612 611.6196 FGFR1 oncogene partner 2 OS=Homo sapiens OX=9606 GN=FGFR1OP2 PE=1 SV=1 4.25 1877.4 - 141757 - - - 0.8576 - 1.425 0.27 - 43.9 1 2 1 0.0016 15 0 0 0 1.71E+06 8.26E+04 - - - 2.474 0.9711 221125_WJC_METTL3_EV_vs_WT_F09.08148.08148.2 0.0401 20-Jun K.EKDFSPEALKK.A "sp|O15372|EIF3H_HUMAN,tr|B3KS98|B3KS98_HUMAN,tr|A0A087WZK9|A0A087WZK9_HUMAN,tr|E5RGU4|E5RGU4_HUMAN,tr|E5RJT0|E5RJT0_HUMAN" 5 1290.682 1.98 128697 8148 2 1290.681943 646.3483 Eukaryotic translation initiation factor 3 subunit H OS=Homo sapiens OX=9606 GN=EIF3H PE=1 SV=1 6.28 1877.5 - 110680 - - - -0.0186 - 1.101 0.307 - 92.2 1 2 1 0 11 0 0 0 7.43E+06 3.74E+06 - - - 1.5688 0.7838 221125_WJC_METTL3_EV_vs_WT_F09.08151.08151.4 0.94 Aug-84 K.LKETGYVVERPSTTK.D "sp|Q9NYF8|BCLF1_HUMAN,tr|E9PKI6|E9PKI6_HUMAN,tr|A0A1W2PQ43|A0A1W2PQ43_HUMAN,tr|E9PK91|E9PK91_HUMAN,tr|E9PK09|E9PK09_HUMAN,tr|E9PQN2|E9PQN2_HUMAN" 6 1706.9203 1.97 128698 8151 4 1706.919946 427.7374 Bcl-2-associated transcription factor 1 OS=Homo sapiens OX=9606 GN=BCLAF1 PE=1 SV=2 8.5 1877.9 - 3.45E+06 - - - -0.2074 - 1.517 0.133 - 35.4 1 2 1 -0.0004 15 0 0 0 1.18E+10 6.01E+09 - - - 0.5326 0.9995 221125_WJC_METTL3_EV_vs_WT_F09.08152.08152.4 0.000863 13/84 K.LK[136.11]ETGYVVER[166.11]PSTTK[136.11].D "sp|Q9NYF8|BCLF1_HUMAN,tr|E9PKI6|E9PKI6_HUMAN,tr|A0A1W2PQ43|A0A1W2PQ43_HUMAN,tr|E9PK91|E9PK91_HUMAN,tr|E9PK09|E9PK09_HUMAN,tr|E9PQN2|E9PQN2_HUMAN" 6 1732.957 1.97 128699 8152 4 1732.955396 434.2465 Bcl-2-associated transcription factor 1 OS=Homo sapiens OX=9606 GN=BCLAF1 PE=1 SV=2 8.5 1878 - 1.45E+06 - - - -0.9083 - 2.265 0.413 - 136.3 1 2 1 -0.0016 15 0 0 0 1.18E+10 6.01E+09 - - - 3.1129 0.9548 221125_WJC_METTL3_EV_vs_WT_F09.08157.08157.3 0.584 Sep-48 K.QGNNNQNK[136.11]PGFLR[166.11].K "sp|Q9P2N5|RBM27_HUMAN,tr|U3KPZ7|U3KPZ7_HUMAN" 2 1503.7661 35.12 128702 8157 3 1503.76559 502.2627 RNA-binding protein 27 OS=Homo sapiens OX=9606 GN=RBM27 PE=1 SV=2 11 1878.7 - 364902 - - - -0.3677 - 1.339 0.142 - 88.9 1 2 0 -0.0006 13 0 0 0 5.93E+08 1.69E+07 - - - 0.9145 0.9999 221125_WJC_METTL3_EV_vs_WT_F09.08159.08159.3 0.000197 14/56 K.LKETGYVVERPSTTK.D "sp|Q9NYF8|BCLF1_HUMAN,tr|E9PKI6|E9PKI6_HUMAN,tr|A0A1W2PQ43|A0A1W2PQ43_HUMAN,tr|E9PK91|E9PK91_HUMAN,tr|E9PK09|E9PK09_HUMAN,tr|E9PQN2|E9PQN2_HUMAN" 6 1706.9203 2.53 128703 8159 3 1706.920952 569.9807 Bcl-2-associated transcription factor 1 OS=Homo sapiens OX=9606 GN=BCLAF1 PE=1 SV=2 8.5 1878.9 - 1.32E+06 - - - 0.382 - 2.765 0.539 - 137 1 2 1 0.0007 15 0 0 0 1.22E+07 4.81E+06 - - - 7.203 0.998 221125_WJC_METTL3_EV_vs_WT_F09.08161.08161.3 4.90E-05 Sep-48 R.SNEK[136.11]EQLQGLNDR[166.11].F "sp|P07197|NFM_HUMAN,tr|E7ESP9|E7ESP9_HUMAN,tr|E7EMV2|E7EMV2_HUMAN" 3 1547.7659 2.98 128705 8161 3 1547.76852 516.9292 Neurofilament medium polypeptide OS=Homo sapiens OX=9606 GN=NEFM PE=1 SV=3 4.68 1879.1 - 580433 - - - 1.7134 - 1.988 0.35 - 102.6 1 2 1 0.0027 13 0 0 0 9.32E+07 3.13E+07 - - - 4.3044 1 221125_WJC_METTL3_EV_vs_WT_F09.08162.08162.3 2.29E-05 Oct-36 K.KDNDFIYHDR.V sp|Q8WUM4|PDC6I_HUMAN 1 1321.6051 0.82 128706 8162 3 1321.603859 441.5423 Programmed cell death 6-interacting protein OS=Homo sapiens OX=9606 GN=PDCD6IP PE=1 SV=1 5.3 1879.3 - 407024 - - - -0.9496 - 1.754 0.516 - 155 1 2 0 -0.0013 10 0 0 0 6.67E+06 8.12E+06 - - - 5.9335 0.9992 221125_WJC_METTL3_EV_vs_WT_F09.08163.08163.3 9.21E-05 Nov-60 R.NAALPTC[160.03]C[160.03]PRPSPAQK.A sp|Q8IY67|RAVR1_HUMAN 1 1766.8556 0.53 128707 8163 3 1766.860809 589.9591 Ribonucleoprotein PTB-binding 1 OS=Homo sapiens OX=9606 GN=RAVER1 PE=1 SV=1 8.96 1879.4 - 289144 - - - 2.9431 - 2.003 0.372 - 89.3 1 2 0 0.0052 16 0 0 0 1.61E+07 3.01E+07 - - - 4.4684 0.9999 221125_WJC_METTL3_EV_vs_WT_F09.08169.08169.3 1.27E-07 19/64 K.AVPKEDIYSGGGGGGSR.S sp|Q13151|ROA0_HUMAN 1 1605.7747 3.12 128711 8169 3 1605.776811 536.2655 Heterogeneous nuclear ribonucleoprotein A0 OS=Homo sapiens OX=9606 GN=HNRNPA0 PE=1 SV=1 6.11 1880.1 - 5.31E+06 - - - 1.3159 - 3.339 0.575 - 355.5 1 2 1 0.0021 17 0 0 0 3.50E+08 1.12E+08 - - - 7.996 0.9982 221125_WJC_METTL3_EV_vs_WT_F09.08175.08175.2 4.43E-05 Sep-32 K.AVPKEDIYSGGGGGGSR.S sp|Q13151|ROA0_HUMAN 1 1605.7747 2.26 128717 8175 2 1605.776109 803.8946 Heterogeneous nuclear ribonucleoprotein A0 OS=Homo sapiens OX=9606 GN=HNRNPA0 PE=1 SV=1 6.11 1880.8 - 133285 - - - 0.8787 - 1.859 0.572 - 188.7 1 2 1 0.0014 17 0 0 0 3.96E+06 1.75E+06 - - - 4.7897 0.9911 221125_WJC_METTL3_EV_vs_WT_F09.08176.08176.2 0.00833 Jun-32 K.AVPK[136.11]EDIYSGGGGGGSR[166.11].S sp|Q13151|ROA0_HUMAN 1 1623.7972 2.26 128718 8176 2 1623.799649 812.9059 Heterogeneous nuclear ribonucleoprotein A0 OS=Homo sapiens OX=9606 GN=HNRNPA0 PE=1 SV=1 6.11 1881 - 97252.8 - - - 1.5279 - 1.48 0.42 - 65.8 1 2 1 0.0025 17 0 0 0 3.96E+06 1.75E+06 - - - 3.1062 0.9912 221125_WJC_METTL3_EV_vs_WT_F09.08183.08183.3 1.43E-05 Nov-60 R.LREDENAEPVGTTYQK.T "sp|Q16643|DREB_HUMAN,tr|D6R9W4|D6R9W4_HUMAN" 2 1848.8854 0.72 128723 8183 3 1848.890301 617.3024 Drebrin OS=Homo sapiens OX=9606 GN=DBN1 PE=1 SV=4 4.41 1882 - 192105 - - - 2.6665 - 2.186 0.278 - 176.9 1 2 1 0.0049 16 0 0 0 3.18E+06 4.38E+06 - - - 3.6448 0.9989 221125_WJC_METTL3_EV_vs_WT_F09.08184.08184.2 1.33E-05 24-Oct R.SNEKEQLQGLNDR.F "sp|P07197|NFM_HUMAN,tr|E7ESP9|E7ESP9_HUMAN,tr|E7EMV2|E7EMV2_HUMAN" 3 1529.7434 6.18 128724 8184 2 1529.743945 765.879 Neurofilament medium polypeptide OS=Homo sapiens OX=9606 GN=NEFM PE=1 SV=3 4.68 1882.1 - 148893 - - - 0.3576 - 2.411 0.551 - 344.3 1 2 1 0.0005 13 0 0 0 4.40E+06 7.11E+05 - - - 5.3692 0.9928 221125_WJC_METTL3_EV_vs_WT_F09.08185.08185.2 0.0486 20-Aug K.EK[136.11]DFSPEALK[136.11]K[136.11].A "sp|O15372|EIF3H_HUMAN,tr|B3KS98|B3KS98_HUMAN,tr|A0A087WZK9|A0A087WZK9_HUMAN,tr|E5RGU4|E5RGU4_HUMAN,tr|E5RJT0|E5RJT0_HUMAN" 5 1314.7246 1.98 128725 8185 2 1314.724574 658.3696 Eukaryotic translation initiation factor 3 subunit H OS=Homo sapiens OX=9606 GN=EIF3H PE=1 SV=1 6.28 1882.2 - 98138.9 - - - 0.0053 - 1.649 0.321 - 161.1 1 2 1 0 11 0 0 0 7.43E+06 3.74E+06 - - - 2.765 1 221125_WJC_METTL3_EV_vs_WT_F09.08187.08187.2 3.86E-08 13/26 K.K[136.11]GPGEVAGTVTGQK[136.11].R "sp|Q86U44|MTA70_HUMAN,tr|F5H6D8|F5H6D8_HUMAN,tr|H0YFV6|H0YFV6_HUMAN,tr|B4DTN4|B4DTN4_HUMAN" 4 1343.738 0.001 128726 8187 2 1343.738626 672.8763 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 8.59 1882.5 - 223447 - - - 0.4815 - 2.631 0.587 - 416.2 1 2 0 0.0006 14 0 0 0 0.00E+00 5.88E+06 - - - 5.8039 1 221125_WJC_METTL3_EV_vs_WT_F09.08189.08189.3 7.88E-13 16/76 H.LGGSSC[160.03]STC[160.03]SAHDPAGPSLK.A sp|Q9H7S9|ZN703_HUMAN 1 1987.8728 1.95 128727 8189 3 1987.874756 663.6315 Zinc finger protein 703 OS=Homo sapiens OX=9606 GN=ZNF703 PE=1 SV=1 6.73 1882.7 - 291125 - - - 0.9965 - 3.356 0.717 - 280.1 1 1 0 0.002 20 0 0 0 2.54E+07 1.31E+07 - - - 9.4706 0.9056 221125_WJC_METTL3_EV_vs_WT_F09.08190.08190.3 2.13E-06 16/76 H.LGGSSC[160.03]STC[160.03]SAHDPAGPSLK[136.11].A sp|Q9H7S9|ZN703_HUMAN 1 1995.887 1.95 128728 8190 3 1996.885089 666.3029 Zinc finger protein 703 OS=Homo sapiens OX=9606 GN=ZNF703 PE=1 SV=1 6.73 1882.8 - 192752 - - - 500.0854 - 2.981 0.627 - 256.2 1 1 0 0.9981 20 0 0 0 2.54E+07 1.31E+07 - - - 7.9038 0.9996 221125_WJC_METTL3_EV_vs_WT_F09.08196.08196.3 7.96E-07 Nov-60 R.LR[166.11]EDENAEPVGTTYQK[136.11].T "sp|Q16643|DREB_HUMAN,tr|D6R9W4|D6R9W4_HUMAN" 2 1866.9078 0.72 128732 8196 3 1866.902272 623.3099 Drebrin OS=Homo sapiens OX=9606 GN=DBN1 PE=1 SV=4 4.41 1883.6 - 177283 - - - -2.983 - 2.099 0.569 - 180.1 1 2 1 -0.0056 16 0 0 0 3.18E+06 4.38E+06 - - - 6.7847 0.9997 221125_WJC_METTL3_EV_vs_WT_F09.08201.08201.3 0.000379 Dec-48 K.NELDQC[160.03]KSDLQNK.T "sp|P52732|KIF11_HUMAN,tr|A0A7I2YQY4|A0A7I2YQY4_HUMAN,tr|A0A7I2V3A9|A0A7I2V3A9_HUMAN,tr|A0A7I2V3V3|A0A7I2V3V3_HUMAN" 4 1590.7308 0.84 128735 8201 3 1590.731325 531.2509 Kinesin-like protein KIF11 OS=Homo sapiens OX=9606 GN=KIF11 PE=1 SV=2 4.56 1884.2 - 460033 - - - 0.3395 - 2.394 0.411 - 171.4 1 2 1 0.0005 13 0 0 0 1.34E+07 1.59E+07 - - - 5.489 0.9985 221125_WJC_METTL3_EV_vs_WT_F09.08202.08202.2 0.0177 22-Dec K.QR[166.11]YPDGIISK[136.11]PK[136.11].N sp|Q86U44|MTA70_HUMAN 1 1426.8143 0 128736 8202 2 1426.814722 714.4144 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 9.7 1884.3 - 894281 - - - 0.3175 - 2.458 0.458 - 316.3 1 2 1 0.0005 12 0 0 0 3.98E+05 8.77E+09 - - - 4.79 0.9995 221125_WJC_METTL3_EV_vs_WT_F09.08214.08214.3 0.00125 Dec-52 R.DQGGFGDR[166.11]NEYGSR[166.11].L "sp|Q92945|FUBP2_HUMAN,tr|M0R0I5|M0R0I5_HUMAN,tr|M0R0C6|M0R0C6_HUMAN,tr|A0A087WTP3|A0A087WTP3_HUMAN" 4 1576.6769 2.21 128743 8214 3 1576.676645 526.5663 Far upstream element-binding protein 2 OS=Homo sapiens OX=9606 GN=KHSRP PE=1 SV=4 4.56 1886 - 587181 - - - -0.1852 - 2.114 0.417 - 159.3 1 2 1 -0.0003 14 0 0 0 2.54E+08 1.15E+08 - - - 5.1784 0.9936 221125_WJC_METTL3_EV_vs_WT_F09.08219.08219.3 0.000114 Sep-40 Q.R[166.11]YPDGIISK[136.11]PK[136.11].N sp|Q86U44|MTA70_HUMAN 1 1298.7557 0 128746 8219 3 1298.756745 433.9258 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 9.7 1886.6 - 753538 - - - 0.8115 - 2.076 0.457 - 112.6 1 1 0 0.0011 11 0 0 0 5.62E+05 5.26E+08 - - - 5.7099 1 221125_WJC_METTL3_EV_vs_WT_F09.08220.08220.2 2.34E-06 26-Dec Y.SQQSSSYGQQSSFR[166.11].Q "sp|Q01844|EWS_HUMAN,tr|B0QYJ7|B0QYJ7_HUMAN,tr|B0QYK0|B0QYK0_HUMAN,tr|F8WC90|F8WC90_HUMAN" 4 1585.6996 0.61 128747 8220 2 1585.702495 793.8571 RNA-binding protein EWS OS=Homo sapiens OX=9606 GN=EWSR1 PE=1 SV=1 8.46 1886.8 - 220889 - - - 1.8049 - 2.777 0.627 - 538.1 1 1 0 0.0029 14 0 0 0 1.02E+07 1.66E+07 - - - 6.2342 1 221125_WJC_METTL3_EV_vs_WT_F09.08222.08222.3 2.47E-06 13/60 K.EVPQDQHLEAPADQSK[136.11].G sp|Q9Y3D9|RT23_HUMAN 1 1798.8577 2.07 128748 8222 3 1798.85496 600.6265 "28S ribosomal protein S23, mitochondrial OS=Homo sapiens OX=9606 GN=MRPS23 PE=1 SV=2" 4.31 1887 - 457487 - - - -1.5265 - 2.476 0.524 - 170.2 1 2 0 -0.0027 16 0 0 0 4.39E+07 2.12E+07 - - - 6.7076 0.9989 221125_WJC_METTL3_EV_vs_WT_F09.08226.08226.3 3.39E-06 13/52 R.DQGGFGDRNEYGSR.L "sp|Q92945|FUBP2_HUMAN,tr|M0R0I5|M0R0I5_HUMAN,tr|M0R0C6|M0R0C6_HUMAN,tr|A0A087WTP3|A0A087WTP3_HUMAN" 4 1556.6604 2.67 128751 8226 3 1556.657238 519.8941 Far upstream element-binding protein 2 OS=Homo sapiens OX=9606 GN=KHSRP PE=1 SV=4 4.56 1887.3 - 1.67E+06 - - - -2.0293 - 2.117 0.396 - 220.8 1 2 1 -0.0032 14 0 0 0 3.12E+08 1.17E+08 - - - 4.9473 0.8003 221125_WJC_METTL3_EV_vs_WT_F09.08231.08231.2 2.95 14-Jun P.DGIISK[136.11]PK[136.11].N sp|Q86U44|MTA70_HUMAN 1 872.5302 0 128754 8231 2 872.528378 437.2724 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 8.59 1888 - 3.17E+06 - - - -2.1088 - 1.291 0.281 - 100 1 1 0 -0.0018 8 0 0 0 2.48E+06 1.99E+09 - - - 1.8862 0.9496 221125_WJC_METTL3_EV_vs_WT_F09.08232.08232.2 5.10E-05 16-Oct Y.PDGIISK[136.11]PK[136.11].N sp|Q86U44|MTA70_HUMAN 1 969.583 0 128755 8232 2 969.5799 485.7988 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 9.01 1888 - 3.20E+06 - - - -3.1787 - 2.059 0.427 - 306.3 1 1 0 -0.0031 9 0 0 0 1.86E+06 1.82E+09 - - - 4.2833 0.9721 221125_WJC_METTL3_EV_vs_WT_F09.08234.08234.2 8.70E-06 26-Nov Y.SQQSSSYGQQSSFR.Q "sp|Q01844|EWS_HUMAN,tr|B0QYJ7|B0QYJ7_HUMAN,tr|B0QYK0|B0QYK0_HUMAN,tr|F8WC90|F8WC90_HUMAN" 4 1575.6914 0.61 128757 8234 2 1575.686246 788.853 RNA-binding protein EWS OS=Homo sapiens OX=9606 GN=EWSR1 PE=1 SV=1 8.46 1888.3 - 320614 - - - -3.2475 - 2.467 0.567 - 331.6 1 1 0 -0.0051 14 0 0 0 1.02E+07 1.66E+07 - - - 5.4933 0.9998 221125_WJC_METTL3_EV_vs_WT_F09.08248.08248.2 0.0233 18-Nov R.YPDGIISK[136.11]PK[136.11].N sp|Q86U44|MTA70_HUMAN 1 1132.6463 0.001 128767 8248 2 1132.64485 567.3304 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 8.5 1890.1 - 645538 - - - -1.289 - 1.945 0.518 - 412.3 1 2 0 -0.0015 10 0 0 0 0.00E+00 1.22E+08 - - - 4.7234 0.9558 221125_WJC_METTL3_EV_vs_WT_F09.08250.08250.3 0.558 Nov-40 K.EKDFSPEALKK.A "sp|O15372|EIF3H_HUMAN,tr|B3KS98|B3KS98_HUMAN,tr|A0A087WZK9|A0A087WZK9_HUMAN,tr|E5RGU4|E5RGU4_HUMAN,tr|E5RJT0|E5RJT0_HUMAN" 5 1290.682 1.87 128768 8250 3 1290.67745 431.2346 Eukaryotic translation initiation factor 3 subunit H OS=Homo sapiens OX=9606 GN=EIF3H PE=1 SV=1 6.28 1890.3 - 2.19E+06 - - - -3.4997 - 1.611 0.268 - 120.5 1 2 1 -0.0045 11 0 0 0 2.41E+08 1.29E+08 - - - 2.8813 0.9998 221125_WJC_METTL3_EV_vs_WT_F09.08259.08259.3 0.000137 Dec-44 K.QR[166.11]YPDGIISKPK[136.11].N sp|Q86U44|MTA70_HUMAN 1 1418.8001 - 128774 8259 3 1418.80127 473.9406 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 9.7 1891.2 - 2.49E+07 - - - 0.8465 - 2.009 0.488 - 226.8 1 2 1 0.0012 12 0 0 0 - - - - - 5.9141 0.9998 221125_WJC_METTL3_EV_vs_WT_F09.08308.08308.3 1.19E-07 14/56 R.QLQDSC[160.03]EEDLSEKEK.A "sp|A6NKD9|CC85C_HUMAN,tr|G3V2D7|G3V2D7_HUMAN,tr|G3V5D5|G3V5D5_HUMAN,tr|H0YJY5|H0YJY5_HUMAN,tr|H0YJE0|H0YJE0_HUMAN" 5 1836.8047 11.04 128790 8308 3 1836.799335 613.2755 Coiled-coil domain-containing protein 85C OS=Homo sapiens OX=9606 GN=CCDC85C PE=1 SV=1 4.08 1897.9 - 937352 - - - -2.9415 - 2.446 0.638 - 152.3 1 2 1 -0.0054 15 0 0 0 3.21E+07 2.91E+06 - - - 7.9855 1 221125_WJC_METTL3_EV_vs_WT_F09.08314.08314.3 1.58E-05 21/48 R.RDSLTGSSDLYKR.T "sp|Q14671|PUM1_HUMAN,tr|Q5T1Z8|Q5T1Z8_HUMAN,tr|H0YDK8|H0YDK8_HUMAN,tr|Q5T1Z4|Q5T1Z4_HUMAN,tr|E9PR38|E9PR38_HUMAN" 5 1496.7583 2.31 128792 8314 3 1496.756971 499.9267 Pumilio homolog 1 OS=Homo sapiens OX=9606 GN=PUM1 PE=1 SV=3 8.59 1898.7 - 1.10E+06 - - - -0.9013 - 3.324 0.566 - 407.9 1 2 0 -0.0013 13 0 0 0 3.87E+07 1.68E+07 - - - 8.1067 0.9905 221125_WJC_METTL3_EV_vs_WT_F09.08365.08365.3 0.000761 Nov-48 R.TNEK[136.11]EQLQGLNDR[166.11].F sp|Q16352|AINX_HUMAN 1 1561.7815 2.2 128807 8365 3 1561.774968 521.6011 Alpha-internexin OS=Homo sapiens OX=9606 GN=INA PE=1 SV=2 4.68 1905.8 - 2.83E+06 - - - -4.1939 - 2.152 0.343 - 176.7 1 2 1 -0.0066 13 0 0 0 1.17E+08 5.32E+07 - - - 4.4402 0.9993 221125_WJC_METTL3_EV_vs_WT_F09.08371.08371.3 7.96E-06 13/48 R.TNEKEQLQGLNDR.F sp|Q16352|AINX_HUMAN 1 1543.759 2.2 128811 8371 3 1543.753082 515.5936 Alpha-internexin OS=Homo sapiens OX=9606 GN=INA PE=1 SV=2 4.68 1906.6 - 3.54E+06 - - - -3.8646 - 2.717 0.512 - 251.3 1 2 1 -0.006 13 0 0 0 1.17E+08 5.32E+07 - - - 6.9567 1 221125_WJC_METTL3_EV_vs_WT_F09.08374.08374.3 0.00198 18/44 K.K[136.11]GESQTDIEITR[166.11].E "sp|P49368|TCPG_HUMAN,tr|B4DUR8|B4DUR8_HUMAN" 2 1393.7168 0.3 128814 8374 3 1393.715057 465.5795 T-complex protein 1 subunit gamma OS=Homo sapiens OX=9606 GN=CCT3 PE=1 SV=4 4.68 1906.9 - 2.35E+06 - - - -1.2456 - 2.683 0.444 - 651.3 1 2 0 -0.0017 12 0 0 0 3.08E+07 1.03E+08 - - - 6.2253 0.9997 221125_WJC_METTL3_EV_vs_WT_F09.08382.08382.3 0.00974 16/56 K.IK[136.11]SEHPGLSIGDTAK[136.11].K "sp|P26583|HMGB2_HUMAN,tr|D6R9A6|D6R9A6_HUMAN" 2 1567.8541 0.25 128817 8382 3 1567.853644 523.6253 High mobility group protein B2 OS=Homo sapiens OX=9606 GN=HMGB2 PE=1 SV=2 6.75 1908 - 2.96E+06 - - - -0.2723 - 3.016 0.39 - 202 1 2 1 -0.0004 15 0 0 0 3.66E+07 1.47E+08 - - - 5.7686 0.9779 221125_WJC_METTL3_EV_vs_WT_F09.08393.08393.3 0.0304 Oct-40 R.QKWEQIEGNSK.L sp|Q10471|GALT2_HUMAN 1 1345.6626 1.35 128822 8393 3 1345.660219 449.5615 Polypeptide N-acetylgalactosaminyltransferase 2 OS=Homo sapiens OX=9606 GN=GALNT2 PE=1 SV=1 6.14 1909.2 - 1.32E+06 - - - -1.7909 - 1.869 0.199 - 184.5 1 2 1 -0.0024 11 0 0 0 1.67E+08 1.24E+08 - - - 2.5347 0.9963 221125_WJC_METTL3_EV_vs_WT_F09.08397.08397.3 0.00386 Dec-40 R.QK[136.11]WEQIEGNSK[136.11].L sp|Q10471|GALT2_HUMAN 1 1361.691 1.35 128824 8397 3 1361.686747 454.9043 Polypeptide N-acetylgalactosaminyltransferase 2 OS=Homo sapiens OX=9606 GN=GALNT2 PE=1 SV=1 6.14 1909.7 - 2.06E+06 - - - -3.1446 - 2.156 0.347 - 208 1 2 1 -0.0043 11 0 0 0 1.67E+08 1.24E+08 - - - 4.59 0.9989 221125_WJC_METTL3_EV_vs_WT_F09.08408.08408.3 5.24E-09 21/64 R.YGDGGSSFQSTTGHC[160.03]VH.M sp|P55795|HNRH2_HUMAN 1 1795.722 - 128828 8408 3 1795.720788 599.5813 Heterogeneous nuclear ribonucleoprotein H2 OS=Homo sapiens OX=9606 GN=HNRNPH2 PE=1 SV=1 5.97 1911.1 - 1.79E+06 - - - -0.6811 - 2.685 0.648 - 247 1 1 0 -0.0012 17 0 0 0 - - - - - 8.2594 0.9987 221125_WJC_METTL3_EV_vs_WT_F09.08414.08414.2 0.000283 20-Oct R.QKWEQIEGNSK.L sp|Q10471|GALT2_HUMAN 1 1345.6626 1.47 128831 8414 2 1345.662918 673.8386 Polypeptide N-acetylgalactosaminyltransferase 2 OS=Homo sapiens OX=9606 GN=GALNT2 PE=1 SV=1 6.14 1911.9 - 979038 - - - 0.2148 - 2 0.558 - 376.8 1 2 1 0.0003 11 0 0 0 2.62E+07 1.79E+07 - - - 5.0374 0.9967 221125_WJC_METTL3_EV_vs_WT_F09.08416.08416.2 7.89E-06 20-Dec R.QK[136.11]WEQIEGNSK[136.11].L sp|Q10471|GALT2_HUMAN 1 1361.691 1.47 128832 8416 2 1361.688222 681.8528 Polypeptide N-acetylgalactosaminyltransferase 2 OS=Homo sapiens OX=9606 GN=GALNT2 PE=1 SV=1 6.14 1912.2 - 769646 - - - -2.0614 - 1.954 0.525 - 442.3 1 2 1 -0.0028 11 0 0 0 2.62E+07 1.79E+07 - - - 4.7299 0.9997 221125_WJC_METTL3_EV_vs_WT_F09.08417.08417.3 0.000114 Nov-52 K.NTPC[160.03]SENK[136.11]LDIQEK[136.11].K "sp|Q9H2U1|DHX36_HUMAN,tr|E7EWK3|E7EWK3_HUMAN" 2 1690.8167 0.95 128833 8417 3 1690.81649 564.6128 ATP-dependent DNA\RNA helicase DHX36 OS=Homo sapiens OX=9606 GN=DHX36 PE=1 SV=2 4.68 1912.3 - 772034 - - - -0.1242 - 2.33 0.425 - 191 1 2 1 -0.0002 14 0 0 0 3.84E+07 4.02E+07 - - - 5.5262 0.9994 221125_WJC_METTL3_EV_vs_WT_F09.08418.08418.3 0.0129 14/52 K.NTPC[160.03]SENKLDIQEK.K "sp|Q9H2U1|DHX36_HUMAN,tr|E7EWK3|E7EWK3_HUMAN" 2 1674.7883 0.95 128834 8418 3 1674.790763 559.27 ATP-dependent DNA\RNA helicase DHX36 OS=Homo sapiens OX=9606 GN=DHX36 PE=1 SV=2 4.68 1912.4 - 739884 - - - 1.4706 - 2.234 0.418 - 273.2 1 2 1 0.0025 14 0 0 0 3.83E+07 4.01E+07 - - - 5.3357 1 221125_WJC_METTL3_EV_vs_WT_F09.08423.08423.3 1.03E-07 17/52 K.TAEEENPEHVEIQK.M sp|O00566|MPP10_HUMAN 1 1651.7689 3.08 128835 8423 3 1651.764604 551.5969 U3 small nucleolar ribonucleoprotein protein MPP10 OS=Homo sapiens OX=9606 GN=MPHOSPH10 PE=1 SV=2 4.32 1913.2 - 1.79E+06 - - - -2.6275 - 2.827 0.623 - 254.6 1 2 0 -0.0043 14 0 0 0 5.23E+07 1.70E+07 - - - 8.2464 1 221125_WJC_METTL3_EV_vs_WT_F09.08431.08431.3 9.68E-09 19/60 K.TATDEAYK[136.11]DPSNLQGK[136.11].V "sp|Q13813|SPTN1_HUMAN,tr|A0A0D9SF54|A0A0D9SF54_HUMAN,tr|A0A0D9SGF6|A0A0D9SGF6_HUMAN" 3 1752.8501 1.47 128841 8431 3 1752.84629 585.2906 "Spectrin alpha chain, non-erythrocytic 1 OS=Homo sapiens OX=9606 GN=SPTAN1 PE=1 SV=3" 4.56 1914.2 - 821228 - - - -2.1782 - 3.115 0.643 - 386.6 1 2 1 -0.0038 16 0 0 0 7.02E+07 4.79E+07 - - - 8.6232 0.9999 221125_WJC_METTL3_EV_vs_WT_F09.08432.08432.3 5.47E-09 17/60 K.TATDEAYKDPSNLQGK.V "sp|Q13813|SPTN1_HUMAN,tr|A0A0D9SF54|A0A0D9SF54_HUMAN,tr|A0A0D9SGF6|A0A0D9SGF6_HUMAN" 3 1736.8217 1.47 128842 8432 3 1736.821442 579.9478 "Spectrin alpha chain, non-erythrocytic 1 OS=Homo sapiens OX=9606 GN=SPTAN1 PE=1 SV=3" 4.56 1914.3 - 1.09E+06 - - - -0.1532 - 2.474 0.599 - 240.6 1 2 1 -0.0003 16 0 0 0 7.03E+07 4.79E+07 - - - 7.5424 0.9968 221125_WJC_METTL3_EV_vs_WT_F09.08436.08436.2 0.112 22-Dec K.QR[166.11]YPDGIISK[136.11]PK[136.11].N sp|Q86U44|MTA70_HUMAN 1 1426.8143 0 128845 8436 2 1426.812158 714.4144 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 9.7 1914.7 - 1.33E+07 - - - -1.4795 - 2.248 0.407 - 327.5 1 2 1 -0.0021 12 0 0 0 3.98E+05 8.77E+09 - - - 4.1778 0.9994 221125_WJC_METTL3_EV_vs_WT_F09.08446.08446.4 0.00306 20/78 R.AIEALHGHELR[166.11]PGR[166.11].A "sp|Q96PK6|RBM14_HUMAN,tr|B8ZZ74|B8ZZ74_HUMAN,tr|F8WDX3|F8WDX3_HUMAN,tr|A0A0A0MSL8|A0A0A0MSL8_HUMAN,tr|A0A0A6YYI9|A0A0A6YYI9_HUMAN" 5 1574.8544 1.63 128852 8446 4 1574.849746 394.7209 RNA-binding protein 14 OS=Homo sapiens OX=9606 GN=RBM14 PE=1 SV=2 6.97 1916 - 749648 - - - -2.9857 - 2.291 0.382 - 373.4 1 2 0 -0.0047 14 0 0 0 2.99E+07 1.84E+07 - - - 2.8513 1 221125_WJC_METTL3_EV_vs_WT_F09.08454.08454.3 5.18E-07 17/64 R.SAAQPSTSPAEVQSLK[136.11]K[136.11].A sp|Q14789|GOGB1_HUMAN 1 1743.9338 1.89 128858 8454 3 1743.933918 582.3185 Golgin subfamily B member 1 OS=Homo sapiens OX=9606 GN=GOLGB1 PE=1 SV=2 8.31 1916.9 - 541873 - - - 0.0803 - 3.091 0.511 - 375.4 1 2 0 0.0001 17 0 0 0 1.49E+07 7.90E+06 - - - 7.088 0.9922 221125_WJC_METTL3_EV_vs_WT_F09.08456.08456.3 0.000124 Dec-40 Q.R[166.11]YPDGIISK[136.11]PK[136.11].N sp|Q86U44|MTA70_HUMAN 1 1298.7557 0 128859 8456 3 1298.753869 433.9258 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 9.7 1917.1 - 866482 - - - -1.4029 - 2.388 0.419 - 276.2 1 1 0 -0.0018 11 0 0 0 3.71E+05 5.25E+08 - - - 5.6837 1 221125_WJC_METTL3_EV_vs_WT_F09.08461.08461.3 0.000101 23/88 R.GGVDTAAAPAGGAPPAHAPGPGR[166.11].D sp|Q14657|LAGE3_HUMAN 1 1960.9743 1.32 128863 8461 3 1960.97172 654.6654 EKC\KEOPS complex subunit LAGE3 OS=Homo sapiens OX=9606 GN=LAGE3 PE=1 SV=2 6.74 1917.7 - 487970 - - - -1.3116 - 3.344 0.561 - 300.2 1 2 0 -0.0026 23 0 0 0 1.25E+07 9.43E+06 - - - 7.6258 1 221125_WJC_METTL3_EV_vs_WT_F09.08462.08462.3 6.97E-07 14/56 K.NQQITHANNTVSNFK.R "sp|Q92598|HS105_HUMAN,tr|A0A0A0MSM0|A0A0A0MSM0_HUMAN,tr|R4GN69|R4GN69_HUMAN" 3 1714.8387 0.14 128864 8462 3 1714.838098 572.6202 Heat shock protein 105 kDa OS=Homo sapiens OX=9606 GN=HSPH1 PE=1 SV=1 8.76 1917.8 - 483952 - - - -0.3487 - 2.652 0.533 - 137.7 1 2 0 -0.0006 15 0 0 0 8.33E+06 5.86E+07 - - - 7.0272 1 221125_WJC_METTL3_EV_vs_WT_F09.08464.08464.2 1.10E-08 28-Nov K.NQQITHANNTVSNFK[136.11].R "sp|Q92598|HS105_HUMAN,tr|A0A0A0MSM0|A0A0A0MSM0_HUMAN,tr|R4GN69|R4GN69_HUMAN" 3 1722.8529 0.001 128866 8464 2 1722.852661 862.4337 Heat shock protein 105 kDa OS=Homo sapiens OX=9606 GN=HSPH1 PE=1 SV=1 8.76 1918.1 - 358738 - - - -0.1364 - 2.36 0.67 - 415.7 1 2 0 -0.0002 15 0 0 0 0.00E+00 3.09E+06 - - - 6.1006 0.9999 221125_WJC_METTL3_EV_vs_WT_F09.08468.08468.4 0.00203 17/78 K.YELISETGGSHDKR.F "sp|Q12906|ILF3_HUMAN,sp|Q96SI9|STRBP_HUMAN" 2 1590.7638 1.14 128868 8468 4 1590.760855 398.6982 Interleukin enhancer-binding factor 3 OS=Homo sapiens OX=9606 GN=ILF3 PE=1 SV=3 5.45 1918.5 - 1.71E+06 - - - -1.8507 - 3.356 0.451 - 291.5 1 2 0 -0.0029 14 0 0 0 7.39E+07 6.51E+07 - - - 3.5913 1 221125_WJC_METTL3_EV_vs_WT_F09.08470.08470.4 9.56E-07 16/78 K.YELISETGGSHDK[136.11]R[166.11].F "sp|Q12906|ILF3_HUMAN,sp|Q96SI9|STRBP_HUMAN" 2 1608.7863 1.14 128870 8470 4 1608.786227 403.2038 Interleukin enhancer-binding factor 3 OS=Homo sapiens OX=9606 GN=ILF3 PE=1 SV=3 5.45 1918.7 - 1.89E+06 - - - -0.0261 - 3.13 0.534 - 297.5 1 2 0 0 14 0 0 0 7.39E+07 6.51E+07 - - - 4.2892 0.9938 221125_WJC_METTL3_EV_vs_WT_F09.08471.08471.2 7.08E-06 26-Nov R.HGSGSGQSSSYSPY.G "sp|Q86YZ3|HORN_HUMAN,sp|Q86YZ3|HORN_HUMAN" 2 1399.564 - 128871 8471 2 1399.563446 700.7893 Hornerin OS=Homo sapiens OX=9606 GN=HRNR PE=1 SV=2 6.74 1918.8 - 613339 - - - -0.4223 - 1.892 0.612 - 207.9 1 1 0 -0.0006 14 0 0 0 - - - - - 5.1612 1 221125_WJC_METTL3_EV_vs_WT_F09.08473.08473.2 2.35E-07 30-Nov K.TATDEAYKDPSNLQGK.V "sp|Q13813|SPTN1_HUMAN,tr|A0A0D9SF54|A0A0D9SF54_HUMAN,tr|A0A0D9SGF6|A0A0D9SGF6_HUMAN" 3 1736.8217 1.18 128873 8473 2 1736.82266 869.4181 "Spectrin alpha chain, non-erythrocytic 1 OS=Homo sapiens OX=9606 GN=SPTAN1 PE=1 SV=3" 4.56 1919.1 - 191693 - - - 0.5481 - 2.359 0.635 - 327.9 1 2 1 0.001 16 0 0 0 1.79E+06 1.52E+06 - - - 5.8408 1 221125_WJC_METTL3_EV_vs_WT_F09.08476.08476.3 3.33E-07 16/56 K.NQQITHANNTVSNFK[136.11].R "sp|Q92598|HS105_HUMAN,tr|A0A0A0MSM0|A0A0A0MSM0_HUMAN,tr|R4GN69|R4GN69_HUMAN" 3 1722.8529 0.14 128874 8476 3 1722.851228 575.2916 Heat shock protein 105 kDa OS=Homo sapiens OX=9606 GN=HSPH1 PE=1 SV=1 8.76 1919.5 - 2.22E+06 - - - -0.9682 - 3.215 0.58 - 461.2 1 2 0 -0.0017 15 0 0 0 8.43E+06 5.88E+07 - - - 8.0533 0.9989 221125_WJC_METTL3_EV_vs_WT_F09.08478.08478.4 0.0101 15/78 R.AIEALHGHELRPGR.A "sp|Q96PK6|RBM14_HUMAN,tr|B8ZZ74|B8ZZ74_HUMAN,tr|F8WDX3|F8WDX3_HUMAN,tr|A0A0A0MSL8|A0A0A0MSL8_HUMAN,tr|A0A0A6YYI9|A0A0A6YYI9_HUMAN" 5 1554.8379 1.59 128876 8478 4 1554.837864 389.7168 RNA-binding protein 14 OS=Homo sapiens OX=9606 GN=RBM14 PE=1 SV=2 6.97 1919.7 - 940148 - - - -0.0283 - 2.27 0.286 - 233 1 2 0 0 14 0 0 0 2.93E+07 1.84E+07 - - - 2.0137 1 221125_WJC_METTL3_EV_vs_WT_F09.08484.08484.3 5.42E-08 16/64 R.TSPSSPAPLPHQEATPR.A "sp|P04920|B3A2_HUMAN,tr|A0A7I2V5T6|A0A7I2V5T6_HUMAN" 2 1771.8853 2.22 128882 8484 3 1771.883454 591.6357 Anion exchange protein 2 OS=Homo sapiens OX=9606 GN=SLC4A2 PE=1 SV=4 6.41 1920.4 - 379402 - - - -1.0486 - 3.069 0.569 - 355.5 1 2 0 -0.0019 17 0 0 0 1.06E+07 4.80E+06 - - - 7.7161 1 221125_WJC_METTL3_EV_vs_WT_F09.08488.08488.3 1.36E-05 19/52 K.YELISETGGSHDK[136.11]R[166.11].F "sp|Q12906|ILF3_HUMAN,sp|Q96SI9|STRBP_HUMAN" 2 1608.7863 1.13 128884 8488 3 1608.785103 537.2694 Interleukin enhancer-binding factor 3 OS=Homo sapiens OX=9606 GN=ILF3 PE=1 SV=3 5.45 1921 - 4.37E+06 - - - -0.7248 - 3.222 0.553 - 486.9 1 2 0 -0.0012 14 0 0 0 8.10E+07 7.14E+07 - - - 7.8144 1 221125_WJC_METTL3_EV_vs_WT_F09.08489.08489.3 3.48E-05 16/52 K.YELISETGGSHDKR.F "sp|Q12906|ILF3_HUMAN,sp|Q96SI9|STRBP_HUMAN" 2 1590.7638 1.13 128885 8489 3 1590.762692 531.2619 Interleukin enhancer-binding factor 3 OS=Homo sapiens OX=9606 GN=ILF3 PE=1 SV=3 5.45 1921.1 - 4.64E+06 - - - -0.6959 - 3.161 0.568 - 318.3 1 2 0 -0.0011 14 0 0 0 8.10E+07 7.14E+07 - - - 7.9309 0.9092 221125_WJC_METTL3_EV_vs_WT_F09.08492.08492.4 0.379 11/102 K.EGDIAVHGVQPGVHEAGK.E sp|Q6UWP8|SBSN_HUMAN 1 1798.8962 39.91 128888 8492 4 1798.896077 450.7313 Suprabasin OS=Homo sapiens OX=9606 GN=SBSN PE=1 SV=2 5.28 1921.4 - 534208 - - - -0.0745 - 2.094 0.108 - 58.2 1 2 0 -0.0001 18 0 0 0 5.06E+06 1.27E+05 - - - 0.4192 1 221125_WJC_METTL3_EV_vs_WT_F09.08501.08501.3 5.07E-07 16/56 R.RWDQTADQTPGATPK.K sp|O75533|SF3B1_HUMAN 1 1670.8012 0.77 128895 8501 3 1670.802432 557.941 Splicing factor 3B subunit 1 OS=Homo sapiens OX=9606 GN=SF3B1 PE=1 SV=3 5.96 1922.4 - 495084 - - - 0.7086 - 2.867 0.543 - 435.7 1 2 0 0.0012 15 0 0 0 5.40E+06 7.01E+06 - - - 7.3419 1 221125_WJC_METTL3_EV_vs_WT_F09.08503.08503.3 0.000102 17/76 R.VPVASPSAHNISSSGGAPDR[166.11].T "sp|Q7KZI7|MARK2_HUMAN,tr|A0A0A0MRU9|A0A0A0MRU9_HUMAN,tr|E7ETY4|E7ETY4_HUMAN,tr|A0A7I2YQF3|A0A7I2YQF3_HUMAN,tr|A0A7I2YQR3|A0A7I2YQR3_HUMAN,tr|E9PC69|E9PC69_HUMAN" 6 1914.9423 1.03 128897 8503 3 1914.938843 639.3214 Serine\threonine-protein kinase MARK2 OS=Homo sapiens OX=9606 GN=MARK2 PE=1 SV=2 6.71 1922.7 - 357694 - - - -1.8173 - 3.813 0.59 - 251.1 1 2 0 -0.0035 20 0 0 0 3.02E+07 2.94E+07 - - - 8.364 1 221125_WJC_METTL3_EV_vs_WT_F09.08512.08512.3 4.18E-07 14/52 K.K[136.11]GPGEVAGTVTGQK[136.11].R "sp|Q86U44|MTA70_HUMAN,tr|F5H6D8|F5H6D8_HUMAN,tr|H0YFV6|H0YFV6_HUMAN,tr|B4DTN4|B4DTN4_HUMAN" 4 1343.738 0.05 128904 8512 3 1343.73883 448.9199 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 8.59 1923.8 - 834402 - - - 0.6333 - 2.764 0.546 - 336.2 1 2 0 0.0009 14 0 0 0 9.95E+05 2.02E+07 - - - 7.329 1 221125_WJC_METTL3_EV_vs_WT_F09.08513.08513.3 9.98E-14 18/76 R.VPVASPSAHNISSSGGAPDR.T "sp|Q7KZI7|MARK2_HUMAN,tr|A0A0A0MRU9|A0A0A0MRU9_HUMAN,tr|E7ETY4|E7ETY4_HUMAN,tr|A0A7I2YQF3|A0A7I2YQF3_HUMAN,tr|A0A7I2YQR3|A0A7I2YQR3_HUMAN,tr|E9PC69|E9PC69_HUMAN" 6 1904.9341 1.03 128905 8513 3 1904.936517 635.9853 Serine\threonine-protein kinase MARK2 OS=Homo sapiens OX=9606 GN=MARK2 PE=1 SV=2 6.71 1923.9 - 538026 - - - 1.2935 - 3.601 0.677 - 291.5 1 2 0 0.0025 20 0 0 0 3.02E+07 2.94E+07 - - - 9.1954 0.9999 221125_WJC_METTL3_EV_vs_WT_F09.08514.08514.3 6.73E-07 13/56 R.R[166.11]WDQTADQTPGATPK[136.11].K sp|O75533|SF3B1_HUMAN 1 1688.8237 0.77 128906 8514 3 1688.828275 563.9485 Splicing factor 3B subunit 1 OS=Homo sapiens OX=9606 GN=SF3B1 PE=1 SV=3 5.96 1924.1 - 480262 - - - 2.6983 - 2.769 0.547 - 128.3 1 2 0 0.0046 15 0 0 0 5.40E+06 7.03E+06 - - - 7.2949 0.9798 221125_WJC_METTL3_EV_vs_WT_F09.08517.08517.3 0.002 Sep-64 R.TSPSSPAPLPHQEATPR[166.11].A "sp|P04920|B3A2_HUMAN,tr|A0A7I2V5T6|A0A7I2V5T6_HUMAN" 2 1781.8936 2.22 128909 8517 3 1782.891959 594.9718 Anion exchange protein 2 OS=Homo sapiens OX=9606 GN=SLC4A2 PE=1 SV=4 6.41 1924.5 - 187180 - - - 560.2899 - 1.933 0.408 - 91.6 1 2 0 0.9984 17 0 0 0 1.06E+07 4.80E+06 - - - 4.4773 0.9997 221125_WJC_METTL3_EV_vs_WT_F09.08518.08518.2 3.54E-05 26-Nov K.K[136.11]GPGEVAGTVTGQK[136.11].R "sp|Q86U44|MTA70_HUMAN,tr|F5H6D8|F5H6D8_HUMAN,tr|H0YFV6|H0YFV6_HUMAN,tr|B4DTN4|B4DTN4_HUMAN" 4 1343.738 0.001 128910 8518 2 1343.735547 672.8763 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 8.59 1924.6 - 171570 - - - -1.8099 - 2.44 0.456 - 296.8 1 2 0 -0.0024 14 0 0 0 0.00E+00 6.96E+06 - - - 4.6467 0.8234 221125_WJC_METTL3_EV_vs_WT_F09.08522.08522.2 0.0344 14-Jun E.TGGSHDKR.F "sp|Q12906|ILF3_HUMAN,sp|Q96SI9|STRBP_HUMAN" 2 856.4151 1.18 128912 8522 2 856.416582 429.2148 Interleukin enhancer-binding factor 3 OS=Homo sapiens OX=9606 GN=ILF3 PE=1 SV=3 8.44 1925.1 - 255126 - - - 1.6978 - 1.068 0.354 - 146.4 1 1 0 0.0015 8 0 0 0 5.33E+06 4.52E+06 - - - 1.8536 0.9998 221125_WJC_METTL3_EV_vs_WT_F09.08526.08526.2 0.000271 26-Aug K.YELISETGGSHDK[136.11]R[166.11].F "sp|Q12906|ILF3_HUMAN,sp|Q96SI9|STRBP_HUMAN" 2 1608.7863 1.74 128916 8526 2 1608.787319 805.4004 Interleukin enhancer-binding factor 3 OS=Homo sapiens OX=9606 GN=ILF3 PE=1 SV=3 5.45 1925.6 - 59130.8 - - - 0.6527 - 1.772 0.474 - 196.9 1 2 0 0.001 14 0 0 0 2.50E+06 1.44E+06 - - - 3.9773 0.9997 221125_WJC_METTL3_EV_vs_WT_F09.08530.08530.3 4.08E-08 13/56 K.SESPQKEDGLSSQLK.S sp|Q96T58|MINT_HUMAN 1 1631.8002 2.14 128918 8530 3 1631.804967 544.9407 Msx2-interacting protein OS=Homo sapiens OX=9606 GN=SPEN PE=1 SV=1 4.68 1926.2 - 338239 - - - 2.8937 - 2.466 0.56 - 136.2 1 2 1 0.0047 15 0 0 0 4.72E+06 2.21E+06 - - - 7.1373 0.9999 221125_WJC_METTL3_EV_vs_WT_F09.08545.08545.3 1.10E-07 15/36 R.TKYEHELALR.Q sp|P08779|K1C16_HUMAN 1 1258.667 286.81 128927 8545 3 1258.668907 420.5629 "Keratin, type I cytoskeletal 16 OS=Homo sapiens OX=9606 GN=KRT16 PE=1 SV=4" 6.42 1928.2 - 600902 - - - 1.5262 - 2.631 0.605 - 340.3 1 2 1 0.0019 10 0 0 0 1.41E+08 4.92E+05 - - - 8.1097 0.9967 221125_WJC_METTL3_EV_vs_WT_F09.08547.08547.3 3.15E-05 Aug-44 K.SIK[136.11]DTIC[160.03]NQDER[166.11].L "sp|Q9ULV4|COR1C_HUMAN,tr|H0YHL7|H0YHL7_HUMAN,tr|B4E3S0|B4E3S0_HUMAN" 3 1495.7056 0.47 128929 8547 3 1495.71173 499.5758 Coronin-1C OS=Homo sapiens OX=9606 GN=CORO1C PE=1 SV=1 4.56 1928.5 - 434702 - - - 4.1138 - 1.865 0.458 - 104.9 1 2 1 0.0062 12 0 0 0 3.53E+06 7.57E+06 - - - 5.3721 0.9251 221125_WJC_METTL3_EV_vs_WT_F09.08548.08548.3 0.00279 Jun-76 K.AQPAQPADEPAEK[136.11]ADEPMEH.- "sp|P25786|PSA1_HUMAN,tr|F5GX11|F5GX11_HUMAN" 2 2167.9572 0.93 128930 8548 3 2167.967686 723.6597 Proteasome subunit alpha type-1 OS=Homo sapiens OX=9606 GN=PSMA1 PE=1 SV=1 4.08 1928.6 - 75767 - - - 4.8539 - 1.41 0.343 - 44.5 1 2 1 0.0105 20 0 0 0 1.44E+06 1.55E+06 - - - 3.1948 0.9972 221125_WJC_METTL3_EV_vs_WT_F09.08553.08553.2 0.034 28-Mar K.SSQPQAGSQGPQTFR[166.11].Q "sp|Q13356|PPIL2_HUMAN,tr|A0A7P0TA15|A0A7P0TA15_HUMAN,tr|A0A7P0TAH4|A0A7P0TAH4_HUMAN,tr|A0A7P0TB19|A0A7P0TB19_HUMAN,tr|A0A7P0Z4K4|A0A7P0Z4K4_HUMAN,tr|A0A7P0T8E8|A0A7P0T8E8_HUMAN" 6 1584.752 0.39 128933 8553 2 1584.753796 793.3833 RING-type E3 ubiquitin-protein ligase PPIL2 OS=Homo sapiens OX=9606 GN=PPIL2 PE=1 SV=1 9.47 1929.3 - 59992.7 - - - 1.1314 - 0.862 0.424 - 17.6 1 2 0 0.0018 15 0 0 0 5.38E+05 1.38E+06 - - - 1.807 0.8767 221125_WJC_METTL3_EV_vs_WT_F09.08554.08554.3 8.06E-07 Nov-60 K.HSGPNSADSANDGFVR[166.11].L sp|P52597|HNRPF_HUMAN 1 1639.7214 -1 128934 8554 3 1640.710027 547.5811 Heterogeneous nuclear ribonucleoprotein F OS=Homo sapiens OX=9606 GN=HNRNPF PE=1 SV=3 5.21 1929.4 - 187156 - - - 602.9048 - 2.024 0.558 - 187.2 1 2 0 0.9886 16 0 0 0 0.00E+00 0.00E+00 - - - 6.2964 0.9997 221125_WJC_METTL3_EV_vs_WT_F09.08558.08558.3 1.22E-07 15/56 K.GQPDVVVKEDEEYKR.V "sp|P24752|THIL_HUMAN,tr|A0A5F9ZHJ7|A0A5F9ZHJ7_HUMAN,tr|A0A5F9ZHD4|A0A5F9ZHD4_HUMAN,tr|A0A5F9ZHJ0|A0A5F9ZHJ0_HUMAN,tr|A0A5F9ZHL1|A0A5F9ZHL1_HUMAN,tr|A0A5F9ZI66|A0A5F9ZI66_HUMAN" 6 1789.8846 1.35 128936 8558 3 1789.89063 597.6355 "Acetyl-CoA acetyltransferase, mitochondrial OS=Homo sapiens OX=9606 GN=ACAT1 PE=1 SV=1" 4.51 1930 - 188424 - - - 3.3449 - 2.99 0.564 - 403.1 1 2 1 0.006 15 0 0 0 8.67E+07 6.43E+07 - - - 7.6844 0.9998 221125_WJC_METTL3_EV_vs_WT_F09.08561.08561.3 2.16E-05 Oct-56 K.NEEPSEEEIDAPK[136.11]PK[136.11].K sp|Q9NR30|DDX21_HUMAN 1 1726.8232 1.23 128939 8561 3 1726.828672 576.615 Nucleolar RNA helicase 2 OS=Homo sapiens OX=9606 GN=DDX21 PE=1 SV=5 4.14 1930.4 - 122992 - - - 3.1543 - 2.021 0.486 - 158.2 1 2 0 0.0054 15 0 0 0 2.01E+08 1.64E+08 - - - 5.7928 0.9998 221125_WJC_METTL3_EV_vs_WT_F09.08570.08570.3 1.09E-07 14/44 K.QR[166.11]YPDGIISK[136.11]PK[136.11].N sp|Q86U44|MTA70_HUMAN 1 1426.8143 0 128945 8570 3 1426.818716 476.612 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 9.7 1931.6 - 6.93E+06 - - - 3.1167 - 2.582 0.6 - 310 1 2 1 0.0044 12 0 0 0 2.13E+08 1.28E+11 - - - 7.8575 0.9998 221125_WJC_METTL3_EV_vs_WT_F09.08572.08572.4 2.32E-09 18/84 K.GQPDVVVK[136.11]EDEEYK[136.11]R[166.11].V "sp|P24752|THIL_HUMAN,tr|A0A5F9ZHJ7|A0A5F9ZHJ7_HUMAN,tr|A0A5F9ZHD4|A0A5F9ZHD4_HUMAN,tr|A0A5F9ZHJ0|A0A5F9ZHJ0_HUMAN,tr|A0A5F9ZHL1|A0A5F9ZHL1_HUMAN,tr|A0A5F9ZI66|A0A5F9ZI66_HUMAN" 6 1815.9213 1.32 128946 8572 4 1815.927283 454.9876 "Acetyl-CoA acetyltransferase, mitochondrial OS=Homo sapiens OX=9606 GN=ACAT1 PE=1 SV=1" 4.51 1931.8 - 844814 - - - 3.2876 - 3.392 0.577 - 340 1 2 1 0.006 15 0 0 0 1.32E+08 1.00E+08 - - - 4.6836 0.9997 221125_WJC_METTL3_EV_vs_WT_F09.08573.08573.4 1.03E-06 17/84 K.GQPDVVVKEDEEYKR.V "sp|P24752|THIL_HUMAN,tr|A0A5F9ZHJ7|A0A5F9ZHJ7_HUMAN,tr|A0A5F9ZHD4|A0A5F9ZHD4_HUMAN,tr|A0A5F9ZHJ0|A0A5F9ZHJ0_HUMAN,tr|A0A5F9ZHL1|A0A5F9ZHL1_HUMAN,tr|A0A5F9ZI66|A0A5F9ZI66_HUMAN" 6 1789.8846 1.32 128947 8573 4 1789.890579 448.4784 "Acetyl-CoA acetyltransferase, mitochondrial OS=Homo sapiens OX=9606 GN=ACAT1 PE=1 SV=1" 4.51 1931.9 - 974491 - - - 3.3164 - 3.431 0.537 - 320.5 1 2 1 0.0059 15 0 0 0 1.32E+08 1.00E+08 - - - 4.3395 0.9995 221125_WJC_METTL3_EV_vs_WT_F09.08577.08577.3 1.22E-05 Oct-76 K.AQPAQPADEPAEKADEPMEH.- "sp|P25786|PSA1_HUMAN,tr|F5GX11|F5GX11_HUMAN" 2 2159.943 0.93 128951 8577 3 2159.950103 720.9883 Proteasome subunit alpha type-1 OS=Homo sapiens OX=9606 GN=PSMA1 PE=1 SV=1 4.08 1932.4 - 81562.4 - - - 3.3056 - 1.99 0.602 - 112.9 1 2 1 0.0071 20 0 0 0 1.44E+06 1.55E+06 - - - 6.9192 1 221125_WJC_METTL3_EV_vs_WT_F09.08580.08580.3 7.14E-07 16/60 K.HTGPNSPDTANDGFVR.L "sp|P55795|HNRH2_HUMAN,sp|P31943|HNRH1_HUMAN,tr|E5RGH4|E5RGH4_HUMAN,tr|E7EQJ0|E7EQJ0_HUMAN,tr|D6RIH9|D6RIH9_HUMAN,tr|D6RJ04|D6RJ04_HUMAN,tr|E5RGV0|E5RGV0_HUMAN,tr|D6RFM3|D6RFM3_HUMAN,tr|E9PCY7|E9PCY7_HUMAN,tr|D6RIT2|D6RIT2_HUMAN,tr|D6R9T0|D6R9T0_HUMAN,tr|D6RIU0|D6RIU0_HUMAN,tr|H0YAQ2|H0YAQ2_HUMAN,tr|D6RAM1|D6RAM1_HUMAN,tr|D6RBM0|D6RBM0_HUMAN,tr|G8JLB6|G8JLB6_HUMAN,tr|D6RDU3|D6RDU3_HUMAN" 17 1683.7601 1.42 128952 8580 3 1683.762624 562.2606 Heterogeneous nuclear ribonucleoprotein H2 OS=Homo sapiens OX=9606 GN=HNRNPH2 PE=1 SV=1 5.21 1932.8 - 695996 - - - 1.4925 - 3.416 0.638 - 377.9 1 2 0 0.0025 16 0 0 0 6.36E+07 4.47E+07 - - - 8.8045 1 221125_WJC_METTL3_EV_vs_WT_F09.08581.08581.3 3.42E-10 13/56 K.NEEPSEEEIDAPKPK.K sp|Q9NR30|DDX21_HUMAN 1 1710.7948 1.21 128953 8581 3 1710.798755 571.2722 Nucleolar RNA helicase 2 OS=Homo sapiens OX=9606 GN=DDX21 PE=1 SV=5 4.14 1933 - 490775 - - - 2.2972 - 2.724 0.642 - 244.9 1 2 0 0.0039 15 0 0 0 1.92E+08 1.59E+08 - - - 8.3114 1 221125_WJC_METTL3_EV_vs_WT_F09.08595.08595.3 1.12E-06 13/60 K.HTGPNSPDTANDGFVR[166.11].L "sp|P55795|HNRH2_HUMAN,sp|P31943|HNRH1_HUMAN,tr|E5RGH4|E5RGH4_HUMAN,tr|E7EQJ0|E7EQJ0_HUMAN,tr|D6RIH9|D6RIH9_HUMAN,tr|D6RJ04|D6RJ04_HUMAN,tr|E5RGV0|E5RGV0_HUMAN,tr|D6RFM3|D6RFM3_HUMAN,tr|E9PCY7|E9PCY7_HUMAN,tr|D6RIT2|D6RIT2_HUMAN,tr|D6R9T0|D6R9T0_HUMAN,tr|D6RIU0|D6RIU0_HUMAN,tr|H0YAQ2|H0YAQ2_HUMAN,tr|D6RAM1|D6RAM1_HUMAN,tr|D6RBM0|D6RBM0_HUMAN,tr|G8JLB6|G8JLB6_HUMAN,tr|D6RDU3|D6RDU3_HUMAN" 17 1693.7684 1.41 128962 8595 3 1693.772122 565.5967 Heterogeneous nuclear ribonucleoprotein H2 OS=Homo sapiens OX=9606 GN=HNRNPH2 PE=1 SV=1 5.21 1934.8 - 1.12E+06 - - - 2.2087 - 2.635 0.527 - 206.9 1 2 0 0.0037 16 0 0 0 6.32E+07 4.47E+07 - - - 6.9005 0.9969 221125_WJC_METTL3_EV_vs_WT_F09.08600.08600.2 0.00317 30-Mar K.HTGPNSPDTANDGFVR[166.11].L "sp|P55795|HNRH2_HUMAN,sp|P31943|HNRH1_HUMAN,tr|E5RGH4|E5RGH4_HUMAN,tr|E7EQJ0|E7EQJ0_HUMAN,tr|D6RIH9|D6RIH9_HUMAN,tr|D6RJ04|D6RJ04_HUMAN,tr|E5RGV0|E5RGV0_HUMAN,tr|D6RFM3|D6RFM3_HUMAN,tr|E9PCY7|E9PCY7_HUMAN,tr|D6RIT2|D6RIT2_HUMAN,tr|D6R9T0|D6R9T0_HUMAN,tr|D6RIU0|D6RIU0_HUMAN,tr|H0YAQ2|H0YAQ2_HUMAN,tr|D6RAM1|D6RAM1_HUMAN,tr|D6RBM0|D6RBM0_HUMAN,tr|G8JLB6|G8JLB6_HUMAN,tr|D6RDU3|D6RDU3_HUMAN" 17 1693.7684 1.36 128967 8600 2 1693.771292 847.8915 Heterogeneous nuclear ribonucleoprotein H2 OS=Homo sapiens OX=9606 GN=HNRNPH2 PE=1 SV=1 5.21 1935.4 - 44127 - - - 1.7187 - 0.917 0.426 - 20.4 1 2 0 0.0029 16 0 0 0 1.31E+06 9.64E+05 - - - 1.9735 0.9998 221125_WJC_METTL3_EV_vs_WT_F09.08604.08604.3 1.32E-07 15/56 K.GQPDVVVK[136.11]EDEEYK[136.11]R[166.11].V "sp|P24752|THIL_HUMAN,tr|A0A5F9ZHJ7|A0A5F9ZHJ7_HUMAN,tr|A0A5F9ZHD4|A0A5F9ZHD4_HUMAN,tr|A0A5F9ZHJ0|A0A5F9ZHJ0_HUMAN,tr|A0A5F9ZHL1|A0A5F9ZHL1_HUMAN,tr|A0A5F9ZI66|A0A5F9ZI66_HUMAN" 6 1815.9213 1.34 128968 8604 3 1815.925756 606.3144 "Acetyl-CoA acetyltransferase, mitochondrial OS=Homo sapiens OX=9606 GN=ACAT1 PE=1 SV=1" 4.51 1936.1 - 1.04E+06 - - - 2.4467 - 3.146 0.513 - 415.2 1 2 1 0.0044 15 0 0 0 8.60E+07 6.40E+07 - - - 7.2489 0.9993 221125_WJC_METTL3_EV_vs_WT_F09.08608.08608.2 0.0232 Jun-38 K.AADPPAENSSAPEAEQGGAE.- "sp|P67809|YBOX1_HUMAN,tr|H0Y449|H0Y449_HUMAN" 2 1896.7973 - 128972 8608 2 1896.797793 949.4059 Y-box-binding protein 1 OS=Homo sapiens OX=9606 GN=YBX1 PE=1 SV=3 3.7 1936.6 - 57919.6 - - - 0.2367 - 1.093 0.471 - 59.1 1 2 0 0.0004 20 0 0 0 - - - - - 2.7383 0.9421 221125_WJC_METTL3_EV_vs_WT_F09.08611.08611.3 0.0261 Aug-48 K.EK[136.11]DIQEESTFSSR[166.11].K "sp|P42704|LPPRC_HUMAN,tr|A0A804HI14|A0A804HI14_HUMAN,tr|A0A804HL40|A0A804HL40_HUMAN,tr|A0A804HKJ0|A0A804HKJ0_HUMAN,tr|A0A804HKR3|A0A804HKR3_HUMAN,tr|A0A0C4DG06|A0A0C4DG06_HUMAN,tr|A0A804HIN4|A0A804HIN4_HUMAN,tr|A0A804HLG8|A0A804HLG8_HUMAN,tr|A0A804HIV5|A0A804HIV5_HUMAN,tr|A0A804HHY9|A0A804HHY9_HUMAN,tr|A0A804HJH8|A0A804HJH8_HUMAN,tr|B8ZZ38|B8ZZ38_HUMAN,tr|A0A804HI40|A0A804HI40_HUMAN,tr|A0A804HJZ1|A0A804HJZ1_HUMAN,tr|C9JCA9|C9JCA9_HUMAN,tr|A0A804HIQ7|A0A804HIQ7_HUMAN,tr|A0A804HK30|A0A804HK30_HUMAN,tr|A0A804HKI2|A0A804HKI2_HUMAN,tr|A0A804HIG4|A0A804HIG4_HUMAN,tr|A0A804HK02|A0A804HK02_HUMAN" 20 1572.7387 1.01 128973 8611 3 1572.739228 525.2535 "Leucine-rich PPR motif-containing protein, mitochondrial OS=Homo sapiens OX=9606 GN=LRPPRC PE=1 SV=3" 4.41 1937 - 286735 - - - 0.3669 - 1.572 0.168 - 99 1 2 1 0.0006 13 0 0 0 3.00E+07 2.98E+07 - - - 1.6393 0.8366 221125_WJC_METTL3_EV_vs_WT_F09.08613.08613.4 0.0559 8/150 K.QVPGGGGGGGSGGGGGSGGGGSGGGR.G "sp|Q9UHB9|SRP68_HUMAN,tr|K7EN53|K7EN53_HUMAN,tr|K7EQC2|K7EQC2_HUMAN" 3 1842.7953 67.06 128975 8613 4 1842.800067 461.7061 Signal recognition particle subunit SRP68 OS=Homo sapiens OX=9606 GN=SRP68 PE=1 SV=2 9.75 1937.3 - 645728 - - - 2.5722 - 1.401 0.21 - 16.2 8 2 0 0.0047 26 0 0 0 2.14E+07 3.19E+05 - - - 0.4706 0.9999 221125_WJC_METTL3_EV_vs_WT_F09.08614.08614.3 6.66E-06 14/64 R.ASAPSPNAQVAC[160.03]DHC[160.03]LK.E "sp|Q14258|TRI25_HUMAN,tr|I3L2W4|I3L2W4_HUMAN,tr|A0A3B3IUA7|A0A3B3IUA7_HUMAN" 3 1824.8247 0.96 128976 8614 3 1824.828415 609.2822 E3 ubiquitin\ISG15 ligase TRIM25 OS=Homo sapiens OX=9606 GN=TRIM25 PE=1 SV=2 6.77 1937.4 - 442329 - - - 2.0342 - 2.564 0.431 - 229.9 1 2 0 0.0037 17 0 0 0 1.96E+07 2.05E+07 - - - 5.7229 0.9992 221125_WJC_METTL3_EV_vs_WT_F09.08622.08622.2 0.000345 16-Aug K.ESEFDDEPK.F "sp|Q9Y2W1|TR150_HUMAN,tr|A0A3B3ITZ9|A0A3B3ITZ9_HUMAN" 2 1094.4404 5.44 128982 8622 2 1094.437602 548.2275 Thyroid hormone receptor-associated protein 3 OS=Homo sapiens OX=9606 GN=THRAP3 PE=1 SV=2 3.83 1938.5 - 247467 - - - -2.5566 - 1.522 0.49 - 248.1 1 2 0 -0.0028 9 0 0 0 1.52E+07 2.79E+06 - - - 3.8744 0.9998 221125_WJC_METTL3_EV_vs_WT_F09.08623.08623.3 0.00129 Jun-60 R.C[160.03]YSHGSQETDEEFDAR.W "sp|P20674|COX5A_HUMAN,tr|H3BNX8|H3BNX8_HUMAN,tr|H3BRI0|H3BRI0_HUMAN" 3 1929.7435 4.21 128983 8623 3 1929.735442 644.2551 "Cytochrome c oxidase subunit 5A, mitochondrial OS=Homo sapiens OX=9606 GN=COX5A PE=1 SV=2" 4.17 1938.6 - 89289.6 - - - -4.1938 - 1.755 0.62 - 49.2 1 2 0 -0.0081 16 0 0 0 1.50E+06 3.56E+05 - - - 6.8934 0.9864 221125_WJC_METTL3_EV_vs_WT_F09.08626.08626.3 0.000389 16/48 Q.PDVVVK[136.11]EDEEYK[136.11]R[166.11].V "sp|P24752|THIL_HUMAN,tr|A0A5F9ZHJ7|A0A5F9ZHJ7_HUMAN,tr|A0A5F9ZHD4|A0A5F9ZHD4_HUMAN,tr|A0A5F9ZHJ0|A0A5F9ZHJ0_HUMAN,tr|A0A5F9ZHL1|A0A5F9ZHL1_HUMAN,tr|A0A5F9ZI66|A0A5F9ZI66_HUMAN" 6 1630.8413 1.07 128984 8626 3 1630.843879 544.621 "Acetyl-CoA acetyltransferase, mitochondrial OS=Homo sapiens OX=9606 GN=ACAT1 PE=1 SV=1" 4.51 1939.1 - 401072 - - - 1.5986 - 3.168 0.492 - 427 1 1 1 0.0026 13 0 0 0 1.56E+07 1.45E+07 - - - 7.151 0.9319 221125_WJC_METTL3_EV_vs_WT_F09.08627.08627.3 0.00024 15/48 M.GHR[166.11]PVLVLSQNTK[136.11].R "sp|P49368|TCPG_HUMAN,tr|E9PM09|E9PM09_HUMAN,tr|E9PRC8|E9PRC8_HUMAN,tr|Q5SZX9|Q5SZX9_HUMAN" 4 1465.8484 0.28 128985 8627 3 1465.852241 489.6234 T-complex protein 1 subunit gamma OS=Homo sapiens OX=9606 GN=CCT3 PE=1 SV=4 11 1939.2 - 382125 - - - 2.6094 - 2.567 0.298 - 464.4 1 1 0 0.0038 13 0 0 0 1.34E+07 4.77E+07 - - - 4.4174 0.9982 221125_WJC_METTL3_EV_vs_WT_F09.08628.08628.2 4.07E-05 18-Sep R.TKYEHELALR.Q sp|P08779|K1C16_HUMAN 1 1258.667 999 128986 8628 2 1258.667184 630.3408 "Keratin, type I cytoskeletal 16 OS=Homo sapiens OX=9606 GN=KRT16 PE=1 SV=4" 6.42 1939.3 - 170765 - - - 0.1573 - 1.653 0.54 - 273.2 1 2 1 0.0002 10 0 0 0 4.64E+06 0.00E+00 - - - 4.4323 0.9997 221125_WJC_METTL3_EV_vs_WT_F09.08633.08633.3 0.0184 Sep-40 R.DHPLPEVAHVK.H "sp|P13073|COX41_HUMAN,tr|Q86WV2|Q86WV2_HUMAN,tr|H3BN72|H3BN72_HUMAN,tr|H3BPG0|H3BPG0_HUMAN,tr|H3BNV9|H3BNV9_HUMAN" 5 1240.6564 1.81 128989 8633 3 1240.65729 414.5594 "Cytochrome c oxidase subunit 4 isoform 1, mitochondrial OS=Homo sapiens OX=9606 GN=COX4I1 PE=1 SV=1" 5.99 1940 - 241524 - - - 0.7004 - 1.812 0.36 - 125.6 1 2 0 0.0009 11 0 0 0 9.22E+06 5.09E+06 - - - 4.2421 0.9992 221125_WJC_METTL3_EV_vs_WT_F09.08636.08636.2 0.00254 28-Jul K.NEEPSEEEIDAPKPK.K sp|Q9NR30|DDX21_HUMAN 1 1710.7948 1.3 128992 8636 2 1710.79953 856.4047 Nucleolar RNA helicase 2 OS=Homo sapiens OX=9606 GN=DDX21 PE=1 SV=5 4.14 1940.4 - 66703 - - - 2.7502 - 1.703 0.495 - 142.7 1 2 0 0.0047 15 0 0 0 5.11E+06 3.94E+06 - - - 4.0045 0.9996 221125_WJC_METTL3_EV_vs_WT_F09.08640.08640.2 0.00458 28-May K.NEEPSEEEIDAPK[136.11]PK[136.11].K sp|Q9NR30|DDX21_HUMAN 1 1726.8232 1.3 128994 8640 2 1726.820896 864.4189 Nucleolar RNA helicase 2 OS=Homo sapiens OX=9606 GN=DDX21 PE=1 SV=5 4.14 1941 - 72374.1 - - - -1.3487 - 1.461 0.492 - 54.2 1 2 0 -0.0023 15 0 0 0 5.11E+06 3.94E+06 - - - 3.6063 0.9595 221125_WJC_METTL3_EV_vs_WT_F09.08643.08643.3 0.0152 Apr-72 K.IKADPDGPEAQAEAC[160.03]SGER.T "sp|Q9NX24|NHP2_HUMAN,tr|J3QSY4|J3QSY4_HUMAN,tr|D6RCB9|D6RCB9_HUMAN,tr|D6RC52|D6RC52_HUMAN" 4 1999.8905 1.17 128997 8643 3 1999.898877 667.6375 H\ACA ribonucleoprotein complex subunit 2 OS=Homo sapiens OX=9606 GN=NHP2 PE=1 SV=1 4.18 1941.4 - 63181.6 - - - 4.1722 - 1.09 0.421 - 10.1 2 2 1 0.0083 19 0 0 0 8.52E+06 7.28E+06 - - - 3.3038 0.9627 221125_WJC_METTL3_EV_vs_WT_F09.08653.08653.3 0.637 May-56 K.NEEPSEEEIDAPK[136.11]PK.K sp|Q9NR30|DDX21_HUMAN 1 1718.809 - 129003 8653 3 1718.808795 573.9436 Nucleolar RNA helicase 2 OS=Homo sapiens OX=9606 GN=DDX21 PE=1 SV=5 4.14 1942.7 - 107875 - - - -0.1338 - 1.044 0.213 - 32.3 1 2 0 -0.0002 15 0 0 0 - - - - - 1.027 0.9997 221125_WJC_METTL3_EV_vs_WT_F09.08656.08656.3 0.000536 Sep-56 K.GGWDHGDTQSIQSSR[166.11].T sp|Q9P206|K1522_HUMAN 1 1639.7214 0.97 129004 8656 3 1639.723791 547.5811 Uncharacterized protein KIAA1522 OS=Homo sapiens OX=9606 GN=KIAA1522 PE=1 SV=2 5.21 1943.1 - 285824 - - - 1.4393 - 1.655 0.411 - 103.1 1 2 0 0.0024 15 0 0 0 6.77E+06 6.95E+06 - - - 4.4362 0.9987 221125_WJC_METTL3_EV_vs_WT_F09.08668.08668.3 0.000885 Aug-56 K.GGWDHGDTQSIQSSR.T sp|Q9P206|K1522_HUMAN 1 1629.7132 0.98 129011 8668 3 1629.713106 544.245 Uncharacterized protein KIAA1522 OS=Homo sapiens OX=9606 GN=KIAA1522 PE=1 SV=2 5.21 1944.8 - 316188 - - - -0.0337 - 1.356 0.339 - 69.1 1 2 0 -0.0001 15 0 0 0 6.77E+06 6.91E+06 - - - 3.1142 0.999 221125_WJC_METTL3_EV_vs_WT_F09.08669.08669.2 2.87E-05 30-Mar K.NSYNNSQAPSPGLGSK[136.11].A sp|Q9UHB7|AFF4_HUMAN 1 1627.7682 0.54 129012 8669 2 1627.768914 814.8914 AF4\FMR2 family member 4 OS=Homo sapiens OX=9606 GN=AFF4 PE=1 SV=1 8.59 1944.9 - 65334.3 - - - 0.4614 - 0.952 0.478 - 14.8 1 2 0 0.0008 16 0 0 0 5.77E+05 1.07E+06 - - - 2.4503 1 221125_WJC_METTL3_EV_vs_WT_F09.08685.08685.2 1.30E-07 15/24 K.GPGEVAGTVTGQK[136.11].R "sp|Q86U44|MTA70_HUMAN,tr|F5H6D8|F5H6D8_HUMAN,tr|H0YFV6|H0YFV6_HUMAN,tr|B4DTN4|B4DTN4_HUMAN" 4 1207.6288 0.01 129020 8685 2 1207.630045 604.8217 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 6 1947 - 1.42E+06 - - - 1.0177 - 3.002 0.649 - 998.1 1 2 0 0.0012 13 0 0 0 6.60E+05 1.06E+08 - - - 6.6555 0.9993 221125_WJC_METTL3_EV_vs_WT_F09.08686.08686.3 0.0331 15/56 K.EKVLATVTKPVGGDK.N "sp|Q02878|RL6_HUMAN,tr|F8VZ45|F8VZ45_HUMAN,tr|F8VWR1|F8VWR1_HUMAN,tr|F8VU16|F8VU16_HUMAN,tr|U3KQR5|U3KQR5_HUMAN,tr|F8VZA3|F8VZA3_HUMAN" 6 1540.8825 0.88 129021 8686 3 1540.884228 514.6348 60S ribosomal protein L6 OS=Homo sapiens OX=9606 GN=RPL6 PE=1 SV=3 8.59 1947.1 - 292502 - - - 1.1487 - 2.343 0.378 - 190.8 1 2 1 0.0018 15 0 0 0 7.39E+06 8.37E+06 - - - 4.9755 0.9999 221125_WJC_METTL3_EV_vs_WT_F09.08691.08691.3 1.11E-06 Dec-72 K.IK[136.11]ADPDGPEAQAEAC[160.03]SGER[166.11].T "sp|Q9NX24|NHP2_HUMAN,tr|J3QSY4|J3QSY4_HUMAN,tr|D6RCB9|D6RCB9_HUMAN,tr|D6RC52|D6RC52_HUMAN" 4 2017.913 1.16 129024 8691 3 2017.914462 673.6449 H\ACA ribonucleoprotein complex subunit 2 OS=Homo sapiens OX=9606 GN=NHP2 PE=1 SV=1 4.18 1947.8 - 222816 - - - 0.723 - 2.438 0.584 - 146.4 1 2 1 0.0015 19 0 0 0 8.88E+06 7.63E+06 - - - 7.2401 0.9281 221125_WJC_METTL3_EV_vs_WT_F09.08698.08698.3 0.182 Aug-44 K.ESESVDKVMDQK.E "sp|Q14103|HNRPD_HUMAN,tr|H0Y8G5|H0Y8G5_HUMAN,tr|D6RF44|D6RF44_HUMAN,tr|D6RBQ9|D6RBQ9_HUMAN,tr|D6RAF8|D6RAF8_HUMAN,tr|H0YA96|H0YA96_HUMAN" 6 1393.6395 2.89 129028 8698 3 1393.639879 465.5538 Heterogeneous nuclear ribonucleoprotein D0 OS=Homo sapiens OX=9606 GN=HNRNPD PE=1 SV=1 4.32 1948.8 - 292478 - - - 0.2648 - 1.227 0.215 - 69.9 1 2 1 0.0004 12 0 0 0 1.82E+07 6.31E+06 - - - 1.504 0.8735 221125_WJC_METTL3_EV_vs_WT_F09.08699.08699.2 3.63 18-Jul R.TKFETEQALR.L "sp|Q04695|K1C17_HUMAN,sp|P08727|K1C19_HUMAN,tr|C9JM50|C9JM50_HUMAN,tr|F5GWP8|F5GWP8_HUMAN" 4 1221.6354 999 129029 8699 2 1221.634983 611.825 "Keratin, type I cytoskeletal 17 OS=Homo sapiens OX=9606 GN=KRT17 PE=1 SV=2" 5.81 1948.9 - 75477.2 - - - -0.3012 - 1.208 0.12 - 112.9 1 2 1 -0.0004 10 0 0 0 1.78E+06 0.00E+00 - - - 0.4547 0.9991 221125_WJC_METTL3_EV_vs_WT_F09.08700.08700.3 0.00241 Nov-60 K.SSTATHPPGPAVQLNK.T sp|Q14684|RRP1B_HUMAN 1 1603.8318 1.06 129030 8700 3 1603.83344 535.6179 Ribosomal RNA processing protein 1 homolog B OS=Homo sapiens OX=9606 GN=RRP1B PE=1 SV=3 8.49 1949 - 286472 - - - 1.0107 - 1.727 0.315 - 112.9 1 2 0 0.0016 16 0 0 0 7.34E+07 6.94E+07 - - - 3.4534 0.8367 221125_WJC_METTL3_EV_vs_WT_F09.08701.08701.3 1.1 May-88 R.GGVDTAAAPAGGAPPAHAPGPGR[166.11].D sp|Q14657|LAGE3_HUMAN 1 1960.9743 0.52 129031 8701 3 1960.973769 654.6654 EKC\KEOPS complex subunit LAGE3 OS=Homo sapiens OX=9606 GN=LAGE3 PE=1 SV=2 6.74 1949.2 - 131065 - - - -0.2667 - 1.023 0.164 - 10.4 4 2 0 -0.0005 23 0 0 0 2.50E+06 4.80E+06 - - - 0.143 1 221125_WJC_METTL3_EV_vs_WT_F09.08707.08707.3 6.39E-05 14/40 M.GHQQLYWSHPR[166.11].K "sp|P62273|RS29_HUMAN,tr|A0A2R8Y851|A0A2R8Y851_HUMAN" 2 1417.6879 1.03 129033 8707 3 1417.690498 473.5699 40S ribosomal protein S29 OS=Homo sapiens OX=9606 GN=RPS29 PE=1 SV=2 8.76 1950.1 - 1.18E+06 - - - 1.8424 - 2.687 0.517 - 424.4 1 2 0 0.0026 11 0 0 0 6.61E+08 6.42E+08 - - - 7.1113 0.9999 221125_WJC_METTL3_EV_vs_WT_F09.08711.08711.3 0.000109 15/40 M.GHQQLYWSHPR.K "sp|P62273|RS29_HUMAN,tr|A0A2R8Y851|A0A2R8Y851_HUMAN" 2 1407.6796 1.03 129035 8711 3 1407.682682 470.2338 40S ribosomal protein S29 OS=Homo sapiens OX=9606 GN=RPS29 PE=1 SV=2 8.76 1950.7 - 1.46E+06 - - - 2.1781 - 2.608 0.499 - 500.3 1 2 0 0.0031 11 0 0 0 6.61E+08 6.42E+08 - - - 6.8257 0.9997 221125_WJC_METTL3_EV_vs_WT_F09.08720.08720.2 1.25E-05 28-Sep K.GSC[160.03]GIGGGIGGGSSR.L "sp|P02533|K1C14_HUMAN,sp|P08779|K1C16_HUMAN,tr|K7ENV3|K7ENV3_HUMAN" 3 1277.5782 999 129040 8720 2 1277.579276 639.7964 "Keratin, type I cytoskeletal 14 OS=Homo sapiens OX=9606 GN=KRT14 PE=1 SV=4" 8.25 1951.9 - 157576 - - - 0.8054 - 1.776 0.458 - 153.5 1 2 0 0.001 15 0 0 0 1.36E+07 0.00E+00 - - - 3.8356 0.9993 221125_WJC_METTL3_EV_vs_WT_F09.08721.08721.3 0.00114 Jul-60 K.ELNNTC[160.03]EPVVTQPK[136.11]PK[136.11].L "sp|Q92598|HS105_HUMAN,tr|Q5TBM3|Q5TBM3_HUMAN,tr|A0A0A0MSM0|A0A0A0MSM0_HUMAN" 3 1868.9637 0.11 129041 8721 3 1868.963442 623.9952 Heat shock protein 105 kDa OS=Homo sapiens OX=9606 GN=HSPH1 PE=1 SV=1 6.23 1952 - 361553 - - - -0.1375 - 1.442 0.369 - 64 1 2 0 -0.0003 16 0 0 0 3.52E+06 3.18E+07 - - - 3.5931 0.9994 221125_WJC_METTL3_EV_vs_WT_F09.08728.08728.2 2.24E-07 20-Oct M.GHQQLYWSHPR.K "sp|P62273|RS29_HUMAN,tr|A0A2R8Y851|A0A2R8Y851_HUMAN" 2 1407.6796 1.06 129046 8728 2 1407.676423 704.8471 40S ribosomal protein S29 OS=Homo sapiens OX=9606 GN=RPS29 PE=1 SV=2 8.76 1953 - 92638.1 - - - -2.2683 - 2.353 0.354 - 402.8 1 2 0 -0.0032 11 0 0 0 1.50E+07 1.41E+07 - - - 3.9695 0.9999 221125_WJC_METTL3_EV_vs_WT_F09.08733.08733.3 5.08E-08 16/60 K.SSTATHPPGPAVQLNK[136.11].T sp|Q14684|RRP1B_HUMAN 1 1611.846 1.06 129049 8733 3 1611.84841 538.2893 Ribosomal RNA processing protein 1 homolog B OS=Homo sapiens OX=9606 GN=RRP1B PE=1 SV=3 8.49 1953.6 - 940625 - - - 1.4834 - 2.942 0.388 - 348.7 1 2 0 0.0024 16 0 0 0 7.26E+07 6.88E+07 - - - 5.634 0.9998 221125_WJC_METTL3_EV_vs_WT_F09.08734.08734.3 0.00255 Oct-52 R.SSSLGSTPHEELER.L "sp|Q9NRA8|4ET_HUMAN,tr|B1AKL4|B1AKL4_HUMAN" 2 1527.7165 1.38 129050 8734 3 1527.716686 510.2461 Eukaryotic translation initiation factor 4E transporter OS=Homo sapiens OX=9606 GN=EIF4ENIF1 PE=1 SV=2 4.75 1953.7 - 192372 - - - 0.1119 - 2.052 0.354 - 171.1 1 2 0 0.0002 14 0 0 0 5.50E+06 3.98E+06 - - - 4.397 0.9993 221125_WJC_METTL3_EV_vs_WT_F09.08735.08735.3 0.000643 Sep-68 R.TTASSELSEKPAESVTSK.K "sp|Q71F23|CENPU_HUMAN,tr|D6R9S4|D6R9S4_HUMAN,tr|Q09GN1|Q09GN1_HUMAN" 3 1850.9109 0.37 129051 8735 3 1850.916028 617.9776 Centromere protein U OS=Homo sapiens OX=9606 GN=CENPU PE=1 SV=1 4.78 1953.9 - 148600 - - - 2.7613 - 1.877 0.398 - 71.4 1 2 0 0.0051 18 0 0 0 3.08E+06 8.26E+06 - - - 4.5438 0.9999 221125_WJC_METTL3_EV_vs_WT_F09.08749.08749.3 0.000302 13/52 K.K[136.11]GPGEVAGTVTGQK[136.11].R "sp|Q86U44|MTA70_HUMAN,tr|F5H6D8|F5H6D8_HUMAN,tr|H0YFV6|H0YFV6_HUMAN,tr|B4DTN4|B4DTN4_HUMAN" 4 1343.738 0.01 129062 8749 3 1343.739031 448.9199 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 8.59 1955.6 - 607504 - - - 0.7829 - 2.403 0.438 - 260.3 1 2 0 0.0011 14 0 0 0 1.65E+05 1.81E+07 - - - 5.7529 1 221125_WJC_METTL3_EV_vs_WT_F09.08750.08750.2 3.91E-09 13/20 M.GHQQLYWSHPR[166.11].K "sp|P62273|RS29_HUMAN,tr|A0A2R8Y851|A0A2R8Y851_HUMAN" 2 1417.6879 1.07 129063 8750 2 1417.690481 709.8512 40S ribosomal protein S29 OS=Homo sapiens OX=9606 GN=RPS29 PE=1 SV=2 8.76 1955.7 - 204320 - - - 1.8304 - 2.94 0.514 - 692.5 1 2 0 0.0026 11 0 0 0 1.51E+07 1.42E+07 - - - 5.7539 0.9996 221125_WJC_METTL3_EV_vs_WT_F09.08758.08758.3 3.99E-05 Oct-64 R.SSEEPTEK[136.11]EPPGQLQVK[136.11].A "sp|Q9ULV3|CIZ1_HUMAN,tr|Q5SYW2|Q5SYW2_HUMAN,tr|F5H2X7|F5H2X7_HUMAN,tr|H0Y5D5|H0Y5D5_HUMAN,tr|A0A494C0L7|A0A494C0L7_HUMAN,tr|Q9BTG3|Q9BTG3_HUMAN" 6 1897.9604 3.36 129069 8758 3 1897.961544 633.6607 Cip1-interacting zinc finger protein OS=Homo sapiens OX=9606 GN=CIZ1 PE=1 SV=2 4.49 1956.7 - 120622 - - - 0.6096 - 2.002 0.462 - 106.7 1 2 1 0.0012 17 0 0 0 1.08E+08 3.22E+07 - - - 5.4441 0.9993 221125_WJC_METTL3_EV_vs_WT_F09.08759.08759.2 0.00213 30-May K.SSTATHPPGPAVQLNK[136.11].T sp|Q14684|RRP1B_HUMAN 1 1611.846 0.91 129070 8759 2 1611.845418 806.9303 Ribosomal RNA processing protein 1 homolog B OS=Homo sapiens OX=9606 GN=RRP1B PE=1 SV=3 8.49 1956.9 - 58150.5 - - - -0.3729 - 1.216 0.43 - 59.4 1 2 0 -0.0006 16 0 0 0 1.63E+06 1.80E+06 - - - 2.6976 0.9724 221125_WJC_METTL3_EV_vs_WT_F09.08763.08763.3 0.00179 Nov-44 K.EKKPGDLSDELR.L "sp|Q13435|SF3B2_HUMAN,tr|E9PPJ0|E9PPJ0_HUMAN,tr|H0YEX5|H0YEX5_HUMAN" 3 1385.7151 1.1 129072 8763 3 1385.71736 462.9123 Splicing factor 3B subunit 2 OS=Homo sapiens OX=9606 GN=SF3B2 PE=1 SV=2 4.78 1957.3 - 1.06E+06 - - - 1.6612 - 1.97 0.177 - 206.2 1 2 1 0.0023 12 0 0 0 2.52E+07 2.29E+07 - - - 2.3921 0.9981 221125_WJC_METTL3_EV_vs_WT_F09.08764.08764.3 3.37E-06 15/60 K.QTAISQPASGNTFSHH.S "sp|Q14157|UBP2L_HUMAN,tr|F8W726|F8W726_HUMAN,tr|Q5VU77|Q5VU77_HUMAN" 3 1681.7808 - 129073 8764 3 1681.781939 561.6009 Ubiquitin-associated protein 2-like OS=Homo sapiens OX=9606 GN=UBAP2L PE=1 SV=2 6.92 1957.4 - 1.10E+06 - - - 0.6499 - 2.686 0.552 - 357.6 1 1 0 0.0011 16 0 0 0 - - - - - 7.2292 0.9997 221125_WJC_METTL3_EV_vs_WT_F09.08765.08765.3 3.41E-05 Oct-44 K.C[160.03]NTDDTIGDLK[136.11]K[136.11].L sp|Q9BZL1|UBL5_HUMAN 1 1394.6682 1.82 129074 8765 3 1394.673546 465.8967 Ubiquitin-like protein 5 OS=Homo sapiens OX=9606 GN=UBL5 PE=1 SV=1 4.43 1957.5 - 618528 - - - 3.8009 - 2.124 0.487 - 123.4 1 2 0 0.0053 12 0 0 0 2.95E+07 1.62E+07 - - - 6.0561 0.9999 221125_WJC_METTL3_EV_vs_WT_F09.08769.08769.3 3.75E-10 15/64 R.SSEEPTEKEPPGQLQVK.A "sp|Q9ULV3|CIZ1_HUMAN,tr|Q5SYW2|Q5SYW2_HUMAN,tr|F5H2X7|F5H2X7_HUMAN,tr|H0Y5D5|H0Y5D5_HUMAN,tr|A0A494C0L7|A0A494C0L7_HUMAN,tr|Q9BTG3|Q9BTG3_HUMAN" 6 1881.932 3.16 129076 8769 3 1881.93405 628.3179 Cip1-interacting zinc finger protein OS=Homo sapiens OX=9606 GN=CIZ1 PE=1 SV=2 4.49 1957.9 - 505436 - - - 1.0962 - 2.856 0.524 - 251.2 1 2 1 0.0021 17 0 0 0 1.10E+08 3.49E+07 - - - 7.0327 1 221125_WJC_METTL3_EV_vs_WT_F09.08771.08771.3 1.16E-07 13/44 K.C[160.03]NTDDTIGDLKK.L sp|Q9BZL1|UBL5_HUMAN 1 1378.6398 1.82 129077 8771 3 1378.641843 460.5539 Ubiquitin-like protein 5 OS=Homo sapiens OX=9606 GN=UBL5 PE=1 SV=1 4.43 1958.2 - 1.14E+06 - - - 1.4493 - 2.324 0.613 - 144.9 1 2 0 0.002 12 0 0 0 2.93E+07 1.61E+07 - - - 7.7113 0.9999 221125_WJC_METTL3_EV_vs_WT_F09.08785.08785.3 1.88E-06 Dec-36 R.TKYEHELALR.Q sp|P08779|K1C16_HUMAN 1 1258.667 34.76 129087 8785 3 1258.667458 420.5629 "Keratin, type I cytoskeletal 16 OS=Homo sapiens OX=9606 GN=KRT16 PE=1 SV=4" 6.42 1960 - 338739 - - - 0.375 - 2.225 0.531 - 236.9 1 2 1 0.0005 10 0 0 0 8.20E+06 2.36E+05 - - - 6.7956 1 221125_WJC_METTL3_EV_vs_WT_F09.08789.08789.3 1.68E-07 14/52 K.R[166.11]PAEDMEEEQAFK[136.11]R[166.11].S "sp|P61978|HNRPK_HUMAN,tr|S4R457|S4R457_HUMAN,tr|Q5T6W2|Q5T6W2_HUMAN" 3 1762.8303 1.39 129089 8789 3 1762.832643 588.6174 Heterogeneous nuclear ribonucleoprotein K OS=Homo sapiens OX=9606 GN=HNRNPK PE=1 SV=1 4.59 1960.6 - 308960 - - - 1.3444 - 2.625 0.61 - 340 1 2 0 0.0024 14 0 0 0 1.19E+08 8.59E+07 - - - 7.905 1 221125_WJC_METTL3_EV_vs_WT_F09.08792.08792.3 1.42E-08 13/56 K.NEEPSEEEIDAPK[136.11]PK[136.11].K sp|Q9NR30|DDX21_HUMAN 1 1726.8232 1.23 129091 8792 3 1726.823747 576.615 Nucleolar RNA helicase 2 OS=Homo sapiens OX=9606 GN=DDX21 PE=1 SV=5 4.14 1961 - 262861 - - - 0.3023 - 2.68 0.586 - 241 1 2 0 0.0005 15 0 0 0 2.01E+08 1.64E+08 - - - 7.6455 1 221125_WJC_METTL3_EV_vs_WT_F09.08793.08793.4 8.49E-06 Dec-78 K.R[166.11]PAEDMEEEQAFK[136.11]R[166.11].S "sp|P61978|HNRPK_HUMAN,tr|S4R457|S4R457_HUMAN,tr|Q5T6W2|Q5T6W2_HUMAN" 3 1762.8303 1.27 129092 8793 4 1762.830559 441.7148 Heterogeneous nuclear ribonucleoprotein K OS=Homo sapiens OX=9606 GN=HNRNPK PE=1 SV=1 4.59 1961.1 - 274242 - - - 0.1622 - 2.102 0.532 - 132.6 1 2 0 0.0003 14 0 0 0 6.44E+07 5.07E+07 - - - 4.1268 0.9993 221125_WJC_METTL3_EV_vs_WT_F09.08797.08797.2 0.1 12-Aug R.FSGVPDR.F "sp|A0A075B6R9|KVD24_HUMAN,sp|A0A0C4DH68|KV224_HUMAN,sp|A2NJV5|KV229_HUMAN,sp|A0A075B6S2|KVD29_HUMAN,sp|A0A0A0MRZ7|KVD26_HUMAN" 5 776.3817 262.8 129095 8797 2 776.381967 389.1981 Probable non-functional immunoglobulin kappa variable 2D-24 OS=Homo sapiens OX=9606 GN=IGKV2D-24 PE=1 SV=1 5.84 1961.6 - 3.54E+06 - - - 0.34 - 1.588 0.303 - 214 1 2 0 0.0003 7 0 0 0 2.67E+08 1.02E+06 - - - 2.7443 0.9998 221125_WJC_METTL3_EV_vs_WT_F09.08802.08802.3 0.000188 Nov-44 K.QR[166.11]YPDGIISK[136.11]PK[136.11].N sp|Q86U44|MTA70_HUMAN 1 1426.8143 0.03 129099 8802 3 1426.814265 476.612 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 9.7 1962.2 - 1.89E+06 - - - -0.0028 - 1.87 0.512 - 148.2 1 2 1 0 12 0 0 0 1.31E+06 3.75E+07 - - - 5.9833 1 221125_WJC_METTL3_EV_vs_WT_F09.08804.08804.3 1.63E-07 16/52 K.RPAEDMEEEQAFKR.S "sp|P61978|HNRPK_HUMAN,tr|S4R457|S4R457_HUMAN,tr|Q5T6W2|Q5T6W2_HUMAN" 3 1734.7995 1.39 129100 8804 3 1734.802203 579.2738 Heterogeneous nuclear ribonucleoprotein K OS=Homo sapiens OX=9606 GN=HNRNPK PE=1 SV=1 4.59 1962.4 - 1.18E+06 - - - 1.5391 - 3.096 0.602 - 387.6 1 2 0 0.0027 14 0 0 0 1.20E+08 8.59E+07 - - - 8.2543 0.9999 221125_WJC_METTL3_EV_vs_WT_F09.08805.08805.3 0.000902 Nov-52 K.HYGYNSYSVSNSEK.D "sp|P07858|CATB_HUMAN,tr|A0A7I2V440|A0A7I2V440_HUMAN,tr|E9PQM1|E9PQM1_HUMAN,tr|A0A7I2V668|A0A7I2V668_HUMAN,tr|A0A7P0NGZ6|A0A7P0NGZ6_HUMAN,tr|A0A7I2YQK9|A0A7I2YQK9_HUMAN,tr|E9PHZ5|E9PHZ5_HUMAN,tr|E9PR21|E9PR21_HUMAN" 8 1633.7009 2 129101 8805 3 1633.704906 545.5742 Cathepsin B OS=Homo sapiens OX=9606 GN=CTSB PE=1 SV=3 6.75 1962.6 - 314055 - - - 2.4735 - 1.873 0.502 - 127.3 1 2 0 0.004 14 0 0 0 6.00E+06 3.00E+06 - - - 5.8034 0.9806 221125_WJC_METTL3_EV_vs_WT_F09.08806.08806.2 0.000751 12-Jul Q.LYWSHPR.K "sp|P62273|RS29_HUMAN,tr|A0A2R8Y851|A0A2R8Y851_HUMAN" 2 957.4821 1.58 129102 8806 2 957.481992 479.7483 40S ribosomal protein S29 OS=Homo sapiens OX=9606 GN=RPS29 PE=1 SV=2 8.75 1962.7 - 520002 - - - -0.0982 - 1.393 0.456 - 214 1 1 0 -0.0001 7 0 0 0 2.04E+07 1.29E+07 - - - 3.4592 1 221125_WJC_METTL3_EV_vs_WT_F09.08810.08810.4 1.26E-06 15/78 K.RPAEDMEEEQAFKR.S "sp|P61978|HNRPK_HUMAN,tr|S4R457|S4R457_HUMAN,tr|Q5T6W2|Q5T6W2_HUMAN" 3 1734.7995 1.27 129104 8810 4 1734.80111 434.7072 Heterogeneous nuclear ribonucleoprotein K OS=Homo sapiens OX=9606 GN=HNRNPK PE=1 SV=1 4.59 1963.2 - 1.06E+06 - - - 0.909 - 3.009 0.517 - 239.1 1 2 0 0.0016 14 0 0 0 6.44E+07 5.08E+07 - - - 4.1265 0.9991 221125_WJC_METTL3_EV_vs_WT_F09.08811.08811.3 0.00199 Jul-64 K.K[136.11]PQEEDSPGPSTSSVLK[136.11].R "sp|Q9BQE4|SELS_HUMAN,tr|E9PN30|E9PN30_HUMAN,tr|A0A182DWI4|A0A182DWI4_HUMAN" 3 1800.9076 1.65 129105 8811 3 1800.910212 601.3098 Selenoprotein S OS=Homo sapiens OX=9606 GN=SELENOS PE=1 SV=3 4.68 1963.4 - 96351.8 - - - 1.4376 - 1.489 0.363 - 48.6 1 2 0 0.0026 17 0 0 0 5.75E+06 3.49E+06 - - - 3.5921 0.9996 221125_WJC_METTL3_EV_vs_WT_F09.08813.08813.3 0.0184 Dec-48 K.SSLHESLHIGQSR.T "sp|P82094|TMF1_HUMAN,tr|F8WF45|F8WF45_HUMAN,tr|A0A2R8Y7M0|A0A2R8Y7M0_HUMAN" 3 1449.7324 3.23 129107 8813 3 1449.733138 484.2514 TATA element modulatory factor OS=Homo sapiens OX=9606 GN=TMF1 PE=1 SV=2 6.66 1963.6 - 388056 - - - 0.4815 - 1.824 0.336 - 126.3 1 2 0 0.0007 13 0 0 0 3.16E+07 9.78E+06 - - - 3.9154 0.9991 221125_WJC_METTL3_EV_vs_WT_F09.08814.08814.3 0.0778 Oct-56 K.NEEPSEEEIDAPKPK.K sp|Q9NR30|DDX21_HUMAN 1 1710.7948 1.23 129108 8814 3 1710.790974 571.2722 Nucleolar RNA helicase 2 OS=Homo sapiens OX=9606 GN=DDX21 PE=1 SV=5 4.14 1963.8 - 221262 - - - -2.251 - 2.159 0.306 - 124.6 1 2 0 -0.0039 15 0 0 0 2.01E+08 1.63E+08 - - - 3.9588 1 221125_WJC_METTL3_EV_vs_WT_F09.08825.08825.3 0.000617 16/60 K.HTGPNSPDTANDGFVR[166.11].L "sp|P55795|HNRH2_HUMAN,sp|P31943|HNRH1_HUMAN,tr|E5RGH4|E5RGH4_HUMAN,tr|E7EQJ0|E7EQJ0_HUMAN,tr|D6RIH9|D6RIH9_HUMAN,tr|D6RJ04|D6RJ04_HUMAN,tr|E5RGV0|E5RGV0_HUMAN,tr|D6RFM3|D6RFM3_HUMAN,tr|E9PCY7|E9PCY7_HUMAN,tr|D6RIT2|D6RIT2_HUMAN,tr|D6R9T0|D6R9T0_HUMAN,tr|D6RIU0|D6RIU0_HUMAN,tr|H0YAQ2|H0YAQ2_HUMAN,tr|D6RAM1|D6RAM1_HUMAN,tr|D6RBM0|D6RBM0_HUMAN,tr|G8JLB6|G8JLB6_HUMAN,tr|D6RDU3|D6RDU3_HUMAN" 17 1693.7684 1.32 129116 8825 3 1693.769154 565.5967 Heterogeneous nuclear ribonucleoprotein H2 OS=Homo sapiens OX=9606 GN=HNRNPH2 PE=1 SV=1 5.21 1965.2 - 3.49E+06 - - - 0.4564 - 3.441 0.564 - 343.1 1 2 0 0.0008 16 0 0 0 3.14E+08 2.37E+08 - - - 7.9986 0.9997 221125_WJC_METTL3_EV_vs_WT_F09.08830.08830.2 0.00442 30-Aug K.HTGPNSPDTANDGFVR.L "sp|P55795|HNRH2_HUMAN,sp|P31943|HNRH1_HUMAN,tr|E5RGH4|E5RGH4_HUMAN,tr|E7EQJ0|E7EQJ0_HUMAN,tr|D6RIH9|D6RIH9_HUMAN,tr|D6RJ04|D6RJ04_HUMAN,tr|E5RGV0|E5RGV0_HUMAN,tr|D6RFM3|D6RFM3_HUMAN,tr|E9PCY7|E9PCY7_HUMAN,tr|D6RIT2|D6RIT2_HUMAN,tr|D6R9T0|D6R9T0_HUMAN,tr|D6RIU0|D6RIU0_HUMAN,tr|H0YAQ2|H0YAQ2_HUMAN,tr|D6RAM1|D6RAM1_HUMAN,tr|D6RBM0|D6RBM0_HUMAN,tr|G8JLB6|G8JLB6_HUMAN,tr|D6RDU3|D6RDU3_HUMAN" 17 1683.7601 1.3 129120 8830 2 1683.76238 842.8873 Heterogeneous nuclear ribonucleoprotein H2 OS=Homo sapiens OX=9606 GN=HNRNPH2 PE=1 SV=1 5.21 1965.8 - 167900 - - - 1.3476 - 1.717 0.492 - 155.7 1 2 0 0.0023 16 0 0 0 1.12E+07 8.60E+06 - - - 4.0032 0.9997 221125_WJC_METTL3_EV_vs_WT_F09.08832.08832.2 0.0595 30-Sep K.HTGPNSPDTANDGFVR[166.11].L "sp|P55795|HNRH2_HUMAN,sp|P31943|HNRH1_HUMAN,tr|E5RGH4|E5RGH4_HUMAN,tr|E7EQJ0|E7EQJ0_HUMAN,tr|D6RIH9|D6RIH9_HUMAN,tr|D6RJ04|D6RJ04_HUMAN,tr|E5RGV0|E5RGV0_HUMAN,tr|D6RFM3|D6RFM3_HUMAN,tr|E9PCY7|E9PCY7_HUMAN,tr|D6RIT2|D6RIT2_HUMAN,tr|D6R9T0|D6R9T0_HUMAN,tr|D6RIU0|D6RIU0_HUMAN,tr|H0YAQ2|H0YAQ2_HUMAN,tr|D6RAM1|D6RAM1_HUMAN,tr|D6RBM0|D6RBM0_HUMAN,tr|G8JLB6|G8JLB6_HUMAN,tr|D6RDU3|D6RDU3_HUMAN" 17 1693.7684 1.3 129121 8832 2 1693.769278 847.8915 Heterogeneous nuclear ribonucleoprotein H2 OS=Homo sapiens OX=9606 GN=HNRNPH2 PE=1 SV=1 5.21 1966 - 120614 - - - 0.5296 - 1.826 0.425 - 159.6 1 2 0 0.0009 16 0 0 0 1.12E+07 8.60E+06 - - - 3.6601 0.9983 221125_WJC_METTL3_EV_vs_WT_F09.08835.08835.3 0.022 Oct-56 R.EHTLQASNQSEIIQK.Q "sp|Q12830|BPTF_HUMAN,tr|A0A2R8Y7Q1|A0A2R8Y7Q1_HUMAN" 2 1724.8693 8.55 129123 8835 3 1724.864483 575.9637 Nucleosome-remodeling factor subunit BPTF OS=Homo sapiens OX=9606 GN=BPTF PE=1 SV=3 5.4 1966.3 - 189770 - - - -2.8083 - 1.894 0.322 - 138.6 1 2 0 -0.0048 15 0 0 0 1.82E+07 2.12E+06 - - - 3.7952 0.9999 221125_WJC_METTL3_EV_vs_WT_F09.08836.08836.3 0.000255 13/48 R.KQSTDEEVTSLAK.S "sp|P23193|TCEA1_HUMAN,tr|E5RJ93|E5RJ93_HUMAN,tr|A0A1W2PRL9|A0A1W2PRL9_HUMAN,tr|A0A1W2PPZ5|A0A1W2PPZ5_HUMAN,tr|E5RIS7|E5RIS7_HUMAN" 5 1434.7202 0.85 129124 8836 3 1434.721253 479.2473 Transcription elongation factor A protein 1 OS=Homo sapiens OX=9606 GN=TCEA1 PE=1 SV=2 4.68 1966.5 - 604913 - - - 0.7319 - 2.501 0.416 - 322.4 1 2 0 0.001 13 0 0 0 3.08E+07 3.61E+07 - - - 5.6631 0.9998 221125_WJC_METTL3_EV_vs_WT_F09.08837.08837.2 4.89E-05 24-Sep R.K[136.11]QSTDEEVTSLAK[136.11].S "sp|P23193|TCEA1_HUMAN,tr|E5RJ93|E5RJ93_HUMAN,tr|A0A1W2PRL9|A0A1W2PRL9_HUMAN,tr|A0A1W2PPZ5|A0A1W2PPZ5_HUMAN,tr|E5RIS7|E5RIS7_HUMAN" 5 1450.7486 1.15 129125 8837 2 1450.746663 726.3816 Transcription elongation factor A protein 1 OS=Homo sapiens OX=9606 GN=TCEA1 PE=1 SV=2 4.68 1966.6 - 180894 - - - -1.3372 - 2.197 0.542 - 198.6 1 2 0 -0.0019 13 0 0 0 1.02E+07 8.80E+06 - - - 5.0637 0.9949 221125_WJC_METTL3_EV_vs_WT_F09.08841.08841.3 0.0087 Aug-48 K.GEFKDEEETVTTK.H sp|Q14677|EPN4_HUMAN 1 1511.6991 1.4 129128 8841 3 1511.695977 504.907 Clathrin interactor 1 OS=Homo sapiens OX=9606 GN=CLINT1 PE=1 SV=1 4.25 1967.1 - 372311 - - - -2.0884 - 1.558 0.356 - 86.2 1 2 1 -0.0032 13 0 0 0 1.07E+07 7.66E+06 - - - 3.7104 0.9986 221125_WJC_METTL3_EV_vs_WT_F09.08843.08843.3 5.91E-11 15/64 R.YGDGGSTFQSTTGHC[160.03]VH.M "sp|P31943|HNRH1_HUMAN,tr|H0YBD7|H0YBD7_HUMAN,tr|H0YB39|H0YB39_HUMAN,tr|H0YBG7|H0YBG7_HUMAN,tr|E9PCY7|E9PCY7_HUMAN,tr|D6RIT2|D6RIT2_HUMAN,tr|G8JLB6|G8JLB6_HUMAN" 7 1809.7377 - 129129 8843 3 1809.740283 604.2532 Heterogeneous nuclear ribonucleoprotein H OS=Homo sapiens OX=9606 GN=HNRNPH1 PE=1 SV=4 5.97 1967.3 - 617045 - - - 1.4488 - 2.565 0.673 - 122.9 1 1 0 0.0026 17 0 0 0 - - - - - 8.4222 0.9977 221125_WJC_METTL3_EV_vs_WT_F09.08844.08844.3 0.00881 Sep-60 R.NGSFGGQYSEC[160.03]RDPAR.E "sp|O43823|AKAP8_HUMAN,tr|A0A7P0TBC8|A0A7P0TBC8_HUMAN,tr|A0A7P0T893|A0A7P0T893_HUMAN,tr|M0QX51|M0QX51_HUMAN" 4 1799.7645 1.2 129130 8844 3 1799.766679 600.9288 A-kinase anchor protein 8 OS=Homo sapiens OX=9606 GN=AKAP8 PE=1 SV=1 6.06 1967.4 - 285570 - - - 1.1857 - 1.817 0.35 - 68.4 1 2 1 0.0021 16 0 0 0 6.64E+06 5.53E+06 - - - 3.9739 0.9999 221125_WJC_METTL3_EV_vs_WT_F09.08848.08848.3 5.14E-05 13/52 K.QGIETPEDQNDLRK.M "sp|Q15637|SF01_HUMAN,tr|A0A7P0T9U7|A0A7P0T9U7_HUMAN" 2 1641.7958 1.37 129132 8848 3 1641.793131 548.2726 Splicing factor 1 OS=Homo sapiens OX=9606 GN=SF1 PE=1 SV=4 4.32 1968 - 265993 - - - -1.6427 - 2.24 0.457 - 233 1 2 0 -0.0027 14 0 0 0 8.32E+06 6.09E+06 - - - 5.7776 0.977 221125_WJC_METTL3_EV_vs_WT_F09.08851.08851.2 0.00832 24-May K.GEFKDEEETVTTK.H sp|Q14677|EPN4_HUMAN 1 1511.6991 4.02 129135 8851 2 1511.699126 756.8568 Clathrin interactor 1 OS=Homo sapiens OX=9606 GN=CLINT1 PE=1 SV=1 4.25 1968.4 - 63675.9 - - - -0.0053 - 1.107 0.332 - 46.3 1 2 1 0 13 0 0 0 1.86E+06 4.63E+05 - - - 1.754 1 221125_WJC_METTL3_EV_vs_WT_F09.08854.08854.2 8.51E-09 20/24 R.KQSTDEEVTSLAK.S "sp|P23193|TCEA1_HUMAN,tr|E5RJ93|E5RJ93_HUMAN,tr|A0A1W2PRL9|A0A1W2PRL9_HUMAN,tr|A0A1W2PPZ5|A0A1W2PPZ5_HUMAN,tr|E5RIS7|E5RIS7_HUMAN" 5 1434.7202 1.15 129136 8854 2 1434.719261 718.3674 Transcription elongation factor A protein 1 OS=Homo sapiens OX=9606 GN=TCEA1 PE=1 SV=2 4.68 1968.8 - 542578 - - - -0.6566 - 3.76 0.628 - 1140.4 1 2 0 -0.0009 13 0 0 0 1.02E+07 8.80E+06 - - - 7.0783 0.9661 221125_WJC_METTL3_EV_vs_WT_F09.08858.08858.2 8.23E-05 18-Jun E.DMEEEQAFKR.S "sp|P61978|HNRPK_HUMAN,tr|S4R457|S4R457_HUMAN,tr|Q5T6W2|Q5T6W2_HUMAN" 3 1281.566 1.34 129140 8858 2 1281.564359 641.7903 Heterogeneous nuclear ribonucleoprotein K OS=Homo sapiens OX=9606 GN=HNRNPK PE=1 SV=1 4.41 1969.3 - 50687.9 - - - -1.2422 - 1.448 0.419 - 129.6 1 1 0 -0.0016 10 0 0 0 8.53E+05 6.35E+05 - - - 3.1685 0.9998 221125_WJC_METTL3_EV_vs_WT_F09.08859.08859.2 1.31E-07 Jun-34 R.NSSSAGSGSGDPSEGLPR[166.11].R "sp|Q8TEB1|DCA11_HUMAN,tr|H0YNK2|H0YNK2_HUMAN,tr|H0YN92|H0YN92_HUMAN,tr|H0YLH4|H0YLH4_HUMAN,tr|H0YN15|H0YN15_HUMAN,tr|H0YN03|H0YN03_HUMAN,tr|H0YLB2|H0YLB2_HUMAN,tr|H0YM86|H0YM86_HUMAN,tr|H0YL64|H0YL64_HUMAN,tr|H0YNT0|H0YNT0_HUMAN,tr|H0YLX7|H0YLX7_HUMAN,tr|H0YMF7|H0YMF7_HUMAN,tr|H0YLQ1|H0YLQ1_HUMAN,tr|H0YKR8|H0YKR8_HUMAN,tr|H0YLF1|H0YLF1_HUMAN,tr|H0YMN6|H0YMN6_HUMAN,tr|H0YM56|H0YM56_HUMAN,tr|H0YNS2|H0YNS2_HUMAN,tr|H0YL29|H0YL29_HUMAN,tr|H0YMZ4|H0YMZ4_HUMAN,tr|H0YN21|H0YN21_HUMAN" 21 1670.7371 0.03 129141 8859 2 1670.73979 836.3758 DDB1- and CUL4-associated factor 11 OS=Homo sapiens OX=9606 GN=DCAF11 PE=1 SV=1 4.37 1969.4 - 53302.5 - - - 1.5855 - 1.441 0.657 - 59.8 1 2 0 0.0027 18 0 0 0 4.05E+04 1.35E+06 - - - 4.791 0.96 221125_WJC_METTL3_EV_vs_WT_F09.08862.08862.4 2.69E-06 19/84 K.NNISSGHVPHGPLTR.P "sp|O95793|STAU1_HUMAN,tr|Q5JW30|Q5JW30_HUMAN" 2 1584.8121 1.91 129142 8862 4 1584.812168 397.2103 Double-stranded RNA-binding protein Staufen homolog 1 OS=Homo sapiens OX=9606 GN=STAU1 PE=1 SV=2 9.76 1969.9 - 346633 - - - 0.0511 - 2.437 0.343 - 179.4 1 1 0 0.0001 15 0 0 0 1.64E+07 8.57E+06 - - - 2.5302 0.9999 221125_WJC_METTL3_EV_vs_WT_F09.08867.08867.3 2.16E-07 Nov-60 K.QSESSHGWTGPSTGVR.Q sp|P20930|FILA_HUMAN 1 1671.7601 0.09 129145 8867 3 1671.764164 558.2606 Filaggrin OS=Homo sapiens OX=9606 GN=FLG PE=1 SV=3 6.75 1970.6 - 360043 - - - 2.4244 - 2.349 0.515 - 189 1 2 0 0.0041 16 0 0 0 3.01E+07 3.38E+08 - - - 6.4718 0.9989 221125_WJC_METTL3_EV_vs_WT_F09.08869.08869.3 4.92E-06 Dec-56 R.EQLEEEEEAK[136.11]HNLEK[136.11].Q sp|P35579|MYH9_HUMAN 1 1869.8927 1.07 129146 8869 3 1869.892504 624.3048 Myosin-9 OS=Homo sapiens OX=9606 GN=MYH9 PE=1 SV=4 4.35 1970.8 - 627597 - - - -0.1054 - 2.644 0.301 - 182.5 1 2 1 -0.0002 15 0 0 0 3.71E+07 3.46E+07 - - - 4.4329 0.9998 221125_WJC_METTL3_EV_vs_WT_F09.08871.08871.4 0.00353 17/84 R.EQLEEEEEAKHNLEK.Q sp|P35579|MYH9_HUMAN 1 1853.8643 1.15 129148 8871 4 1853.866479 464.4734 Myosin-9 OS=Homo sapiens OX=9606 GN=MYH9 PE=1 SV=4 4.35 1971 - 771703 - - - 1.1748 - 2.862 0.458 - 288.1 1 2 1 0.0022 15 0 0 0 5.04E+07 4.39E+07 - - - 3.5881 0.9999 221125_WJC_METTL3_EV_vs_WT_F09.08873.08873.3 8.15E-10 16/56 R.THYSNIEANESEEVR.Q "sp|P04632|CPNS1_HUMAN,tr|A0A075B7C0|A0A075B7C0_HUMAN,tr|A0A0C4DGQ5|A0A0C4DGQ5_HUMAN,tr|K7ELJ7|K7ELJ7_HUMAN,tr|U3KQE2|U3KQE2_HUMAN,tr|K7EIV0|K7EIV0_HUMAN,tr|K7EM73|K7EM73_HUMAN" 7 1776.7915 1.24 129150 8873 3 1776.784783 593.2711 Calpain small subunit 1 OS=Homo sapiens OX=9606 GN=CAPNS1 PE=1 SV=1 4.48 1971.3 - 306693 - - - -3.7641 - 2.639 0.64 - 363.2 1 2 0 -0.0067 15 0 0 0 7.24E+06 5.82E+06 - - - 8.2056 0.9999 221125_WJC_METTL3_EV_vs_WT_F09.08877.08877.4 0.000668 16/84 R.QELSHALYQHDAAC[160.03]R[166.11].V "sp|Q9UMS4|PRP19_HUMAN,tr|F5GY56|F5GY56_HUMAN,tr|F5H2I0|F5H2I0_HUMAN" 3 1807.8299 1.22 129152 8877 4 1807.829548 452.9648 Pre-mRNA-processing factor 19 OS=Homo sapiens OX=9606 GN=PRPF19 PE=1 SV=1 5.99 1971.8 - 749322 - - - -0.2146 - 2.383 0.429 - 267.8 1 2 0 -0.0004 15 0 0 0 8.09E+07 6.61E+07 - - - 3.2706 0.9993 221125_WJC_METTL3_EV_vs_WT_F09.08878.08878.4 6.59E-07 18/84 R.QELSHALYQHDAAC[160.03]R.V "sp|Q9UMS4|PRP19_HUMAN,tr|F5GY56|F5GY56_HUMAN,tr|F5H2I0|F5H2I0_HUMAN" 3 1797.8217 1.22 129153 8878 4 1797.826881 450.4627 Pre-mRNA-processing factor 19 OS=Homo sapiens OX=9606 GN=PRPF19 PE=1 SV=1 5.99 1972 - 666139 - - - 2.9007 - 2.681 0.358 - 315.5 1 2 0 0.0052 15 0 0 0 8.09E+07 6.61E+07 - - - 2.6935 0.9998 221125_WJC_METTL3_EV_vs_WT_F09.08879.08879.4 2.47E-05 18/84 R.EQLEEEEEAK[136.11]HNLEK[136.11].Q sp|P35579|MYH9_HUMAN 1 1869.8927 1.15 129154 8879 4 1869.894461 468.4805 Myosin-9 OS=Homo sapiens OX=9606 GN=MYH9 PE=1 SV=4 4.35 1972.1 - 1.13E+06 - - - 0.9412 - 3.296 0.481 - 325.1 1 2 1 0.0018 15 0 0 0 5.05E+07 4.39E+07 - - - 3.8389 1 221125_WJC_METTL3_EV_vs_WT_F09.08884.08884.3 8.43E-09 21/56 R.QELSHALYQHDAAC[160.03]R.V "sp|Q9UMS4|PRP19_HUMAN,tr|F5GY56|F5GY56_HUMAN,tr|F5H2I0|F5H2I0_HUMAN" 3 1797.8217 1.12 129157 8884 3 1797.823427 600.2812 Pre-mRNA-processing factor 19 OS=Homo sapiens OX=9606 GN=PRPF19 PE=1 SV=1 5.99 1972.7 - 889230 - - - 0.9795 - 3.668 0.571 - 799.5 1 2 0 0.0018 15 0 0 0 7.30E+07 6.52E+07 - - - 8.2969 0.9335 221125_WJC_METTL3_EV_vs_WT_F09.08888.08888.4 0.0535 Nov-84 K.NNISSGHVPHGPLTR[166.11].P "sp|O95793|STAU1_HUMAN,tr|Q5JW30|Q5JW30_HUMAN" 2 1594.8204 2.76 129161 8888 4 1594.822061 399.7124 Double-stranded RNA-binding protein Staufen homolog 1 OS=Homo sapiens OX=9606 GN=STAU1 PE=1 SV=2 9.76 1973.3 - 116592 - - - 1.0685 - 1.924 0.324 - 98.1 1 1 0 0.0017 15 0 0 0 1.52E+07 5.51E+06 - - - 2.2798 1 221125_WJC_METTL3_EV_vs_WT_F09.08893.08893.3 1.59E-06 18/56 R.QELSHALYQHDAAC[160.03]R[166.11].V "sp|Q9UMS4|PRP19_HUMAN,tr|F5GY56|F5GY56_HUMAN,tr|F5H2I0|F5H2I0_HUMAN" 3 1807.8299 1.12 129164 8893 3 1807.831918 603.6173 Pre-mRNA-processing factor 19 OS=Homo sapiens OX=9606 GN=PRPF19 PE=1 SV=1 5.99 1973.9 - 1.51E+06 - - - 1.0963 - 3.228 0.557 - 347.1 1 2 0 0.002 15 0 0 0 7.30E+07 6.53E+07 - - - 7.8073 1 221125_WJC_METTL3_EV_vs_WT_F09.08897.08897.3 1.12E-09 20/60 R.RADLNQGIGEPQSPSR.R sp|Q96C19|EFHD2_HUMAN 1 1723.8602 1.55 129166 8897 3 1723.860582 575.6273 EF-hand domain-containing protein D2 OS=Homo sapiens OX=9606 GN=EFHD2 PE=1 SV=1 6.07 1974.5 - 418751 - - - 0.2454 - 3.648 0.617 - 635.8 1 2 0 0.0004 16 0 0 0 1.67E+07 1.07E+07 - - - 8.7395 0.9999 221125_WJC_METTL3_EV_vs_WT_F09.08899.08899.3 0.000117 13/68 K.NKPGPYSSVPPPSAPPPK.K "sp|Q14978|NOLC1_HUMAN,tr|A0A0A0MRM9|A0A0A0MRM9_HUMAN,tr|S4R349|S4R349_HUMAN" 3 1815.9519 2.53 129168 8899 3 1815.955544 606.3246 Nucleolar and coiled-body phosphoprotein 1 OS=Homo sapiens OX=9606 GN=NOLC1 PE=1 SV=2 9.7 1974.7 - 396265 - - - 1.9874 - 2.823 0.454 - 217.4 1 2 0 0.0036 18 0 0 0 3.32E+07 1.31E+07 - - - 6.1849 1 221125_WJC_METTL3_EV_vs_WT_F09.08905.08905.3 4.29E-07 19/60 R.R[166.11]ADLNQGIGEPQSPSR[166.11].R sp|Q96C19|EFHD2_HUMAN 1 1743.8767 1.55 129172 8905 3 1743.879003 582.2995 EF-hand domain-containing protein D2 OS=Homo sapiens OX=9606 GN=EFHD2 PE=1 SV=1 6.07 1975.5 - 285803 - - - 1.3212 - 3.871 0.568 - 513.6 1 2 0 0.0023 16 0 0 0 1.67E+07 1.07E+07 - - - 8.3449 0.9997 221125_WJC_METTL3_EV_vs_WT_F09.08907.08907.3 0.151 Nov-68 K.NK[136.11]PGPYSSVPPPSAPPPK[136.11].K "sp|Q14978|NOLC1_HUMAN,tr|A0A0A0MRM9|A0A0A0MRM9_HUMAN,tr|S4R349|S4R349_HUMAN" 3 1831.9803 2.54 129174 8907 3 1831.981334 611.6674 Nucleolar and coiled-body phosphoprotein 1 OS=Homo sapiens OX=9606 GN=NOLC1 PE=1 SV=2 9.7 1975.8 - 153474 - - - 0.5453 - 2.269 0.322 - 134.2 1 2 0 0.001 18 0 0 0 3.46E+07 1.36E+07 - - - 4.1699 0.9964 221125_WJC_METTL3_EV_vs_WT_F09.08914.08914.2 0.00344 26-Apr R.GNLGAGNGNLQGPR.H "sp|P43243|MATR3_HUMAN,tr|D6RE02|D6RE02_HUMAN,tr|B3KM87|B3KM87_HUMAN,tr|A8MXP9|A8MXP9_HUMAN,tr|D6RAY2|D6RAY2_HUMAN,tr|D6R991|D6R991_HUMAN,tr|A0A0R4J2E8|A0A0R4J2E8_HUMAN,tr|D6RAM9|D6RAM9_HUMAN,tr|D6RIA2|D6RIA2_HUMAN,tr|H0Y8T4|H0Y8T4_HUMAN,tr|D6REM6|D6REM6_HUMAN,tr|D6RBI2|D6RBI2_HUMAN" 12 1323.6644 1.53 129178 8914 2 1323.664532 662.8395 Matrin-3 OS=Homo sapiens OX=9606 GN=MATR3 PE=1 SV=2 9.75 1976.7 - 50468.5 - - - 0.1299 - 1.173 0.286 - 48.6 3 2 0 0.0002 14 0 0 0 5.36E+06 3.49E+06 - - - 1.3406 1 221125_WJC_METTL3_EV_vs_WT_F09.08925.08925.2 1.47E-06 30-Oct Q.SSSSSGSVFGSGNTGR.G "sp|P35658|NU214_HUMAN,tr|A0A494C0Y1|A0A494C0Y1_HUMAN,tr|A0A0A0MSW3|A0A0A0MSW3_HUMAN,tr|B7ZAV2|B7ZAV2_HUMAN,tr|A0A494C1F2|A0A494C1F2_HUMAN,tr|H0Y837|H0Y837_HUMAN" 6 1472.6492 0.09 129184 8925 2 1472.65001 737.3319 Nuclear pore complex protein Nup214 OS=Homo sapiens OX=9606 GN=NUP214 PE=1 SV=2 9.47 1978.3 - 160985 - - - 0.5745 - 2.323 0.63 - 264.7 1 1 0 0.0008 16 0 0 0 5.06E+06 5.90E+07 - - - 5.7661 0.9991 221125_WJC_METTL3_EV_vs_WT_F09.08932.08932.3 2.19E-07 Dec-52 R.DRVVVVSHDENLC[160.03]R.Q sp|Q7L5L3|GDPD3_HUMAN 1 1696.8315 10.84 129189 8932 3 1696.835242 566.6178 Lysophospholipase D GDPD3 OS=Homo sapiens OX=9606 GN=GDPD3 PE=1 SV=3 5.38 1979.2 - 223424 - - - 2.2041 - 2.379 0.405 - 142.6 1 2 1 0.0037 14 0 0 0 3.87E+06 3.57E+05 - - - 5.3575 0.9999 221125_WJC_METTL3_EV_vs_WT_F09.08939.08939.3 1.05E-05 Sep-68 R.QSPFASSSEHSSENGSLR[166.11].F "sp|Q9H165|BC11A_HUMAN,tr|A0A2U3TZJ5|A0A2U3TZJ5_HUMAN" 2 1915.8536 1.2 129194 8939 3 1915.858193 639.6251 B-cell lymphoma\leukemia 11A OS=Homo sapiens OX=9606 GN=BCL11A PE=1 SV=2 5.4 1980.1 - 136480 - - - 2.4146 - 2.136 0.513 - 102.7 1 2 0 0.0046 18 0 0 0 2.58E+06 2.14E+06 - - - 6.148 1 221125_WJC_METTL3_EV_vs_WT_F09.08941.08941.3 1.97E-05 14/40 M.GHQQLYWSHPR[166.11].K "sp|P62273|RS29_HUMAN,tr|A0A2R8Y851|A0A2R8Y851_HUMAN" 2 1417.6879 1.36 129195 8941 3 1417.690525 473.5699 40S ribosomal protein S29 OS=Homo sapiens OX=9606 GN=RPS29 PE=1 SV=2 8.76 1980.4 - 1.19E+06 - - - 1.8615 - 2.609 0.512 - 445.6 1 2 0 0.0026 11 0 0 0 4.58E+07 3.37E+07 - - - 6.9718 0.9994 221125_WJC_METTL3_EV_vs_WT_F09.08943.08943.3 0.0033 Jul-52 K.TEQGPQVDETQFK[136.11]K[136.11].L "sp|P05091|ALDH2_HUMAN,tr|S4R3S4|S4R3S4_HUMAN" 2 1649.8232 1.03 129196 8943 3 1649.825761 550.9483 "Aldehyde dehydrogenase, mitochondrial OS=Homo sapiens OX=9606 GN=ALDH2 PE=1 SV=2" 4.68 1980.7 - 337142 - - - 1.5735 - 1.477 0.402 - 42.4 1 2 0 0.0026 14 0 0 0 6.15E+06 5.94E+06 - - - 4.0577 1 221125_WJC_METTL3_EV_vs_WT_F09.08949.08949.3 2.03E-07 15/40 M.GHQQLYWSHPR.K "sp|P62273|RS29_HUMAN,tr|A0A2R8Y851|A0A2R8Y851_HUMAN" 2 1407.6796 1.36 129201 8949 3 1407.682843 470.2338 40S ribosomal protein S29 OS=Homo sapiens OX=9606 GN=RPS29 PE=1 SV=2 8.76 1981.4 - 1.20E+06 - - - 2.2924 - 2.697 0.559 - 489.8 1 2 0 0.0032 11 0 0 0 4.56E+07 3.35E+07 - - - 7.5899 1 221125_WJC_METTL3_EV_vs_WT_F09.08960.08960.3 3.24E-07 21/52 R.K[136.11]NPLPPSVGVVDK[136.11]K[136.11].E sp|Q8NC51|PAIRB_HUMAN 1 1500.909 0.77 129209 8960 3 1500.911867 501.3103 Plasminogen activator inhibitor 1 RNA-binding protein OS=Homo sapiens OX=9606 GN=SERBP1 PE=1 SV=2 9.7 1982.8 - 661593 - - - 1.9008 - 3.919 0.633 - 737 1 2 0 0.0029 14 0 0 0 4.86E+07 6.33E+07 - - - 9.2263 1 221125_WJC_METTL3_EV_vs_WT_F09.08962.08962.3 9.90E-06 21/56 R.KLDYGQHVVAGTPGR.V "sp|P38919|IF4A3_HUMAN,tr|I3L3H2|I3L3H2_HUMAN" 2 1596.8372 1.57 129211 8962 3 1596.841218 533.2864 Eukaryotic initiation factor 4A-III OS=Homo sapiens OX=9606 GN=EIF4A3 PE=1 SV=4 8.6 1983 - 1.97E+06 - - - 2.4918 - 3.09 0.559 - 628.2 1 2 0 0.004 15 0 0 0 1.66E+08 1.05E+08 - - - 7.715 0.9999 221125_WJC_METTL3_EV_vs_WT_F09.08963.08963.4 0.002 Dec-84 R.K[136.11]LDYGQHVVAGTPGR[166.11].V "sp|P38919|IF4A3_HUMAN,tr|I3L3H2|I3L3H2_HUMAN" 2 1614.8597 1.88 129212 8963 4 1614.862291 404.7222 Eukaryotic initiation factor 4A-III OS=Homo sapiens OX=9606 GN=EIF4A3 PE=1 SV=4 8.6 1983.1 - 351254 - - - 1.5989 - 2.304 0.423 - 128.3 1 2 0 0.0026 15 0 0 0 4.06E+07 2.16E+07 - - - 3.2057 0.9999 221125_WJC_METTL3_EV_vs_WT_F09.08965.08965.3 3.48E-05 Oct-68 R.QSPFASSSEHSSENGSLR.F "sp|Q9H165|BC11A_HUMAN,tr|A0A2U3TZJ5|A0A2U3TZJ5_HUMAN" 2 1905.8453 1.2 129214 8965 3 1905.848653 636.289 B-cell lymphoma\leukemia 11A OS=Homo sapiens OX=9606 GN=BCL11A PE=1 SV=2 5.4 1983.3 - 162635 - - - 1.7609 - 2.245 0.513 - 117.7 1 2 0 0.0034 18 0 0 0 2.58E+06 2.14E+06 - - - 6.2723 1 221125_WJC_METTL3_EV_vs_WT_F09.08968.08968.3 1.03E-08 20/56 R.K[136.11]LDYGQHVVAGTPGR[166.11].V "sp|P38919|IF4A3_HUMAN,tr|I3L3H2|I3L3H2_HUMAN" 2 1614.8597 1.57 129215 8968 3 1614.862656 539.2938 Eukaryotic initiation factor 4A-III OS=Homo sapiens OX=9606 GN=EIF4A3 PE=1 SV=4 8.6 1983.8 - 2.46E+06 - - - 1.8249 - 3.224 0.625 - 584.8 1 2 0 0.0029 15 0 0 0 1.66E+08 1.05E+08 - - - 8.5619 1 221125_WJC_METTL3_EV_vs_WT_F09.08969.08969.3 3.31E-05 19/52 R.KNPLPPSVGVVDKK.E sp|Q8NC51|PAIRB_HUMAN 1 1476.8664 0.77 129216 8969 3 1476.869635 493.2961 Plasminogen activator inhibitor 1 RNA-binding protein OS=Homo sapiens OX=9606 GN=SERBP1 PE=1 SV=2 9.7 1983.9 - 731598 - - - 2.181 - 3.406 0.617 - 514.6 1 2 0 0.0032 14 0 0 0 4.86E+07 6.32E+07 - - - 8.675 1 221125_WJC_METTL3_EV_vs_WT_F09.08977.08977.3 9.06E-09 18/60 R.HGGGGGGFGGGGFGSR.S sp|P35908|K22E_HUMAN 1 1319.5755 114.94 129222 8977 3 1319.577844 440.8658 "Keratin, type II cytoskeletal 2 epidermal OS=Homo sapiens OX=9606 GN=KRT2 PE=1 SV=2" 9.76 1985 - 890913 - - - 1.7422 - 2.587 0.622 - 239.9 1 2 0 0.0023 16 0 0 0 1.70E+08 1.48E+06 - - - 7.9129 0.9999 221125_WJC_METTL3_EV_vs_WT_F09.08987.08987.2 5.47E-07 30-Nov R.HGGGGGGFGGGGFGSR.S sp|P35908|K22E_HUMAN 1 1319.5755 9.34 129230 8987 2 1319.576388 660.795 "Keratin, type II cytoskeletal 2 epidermal OS=Homo sapiens OX=9606 GN=KRT2 PE=1 SV=2" 9.76 1986.4 - 208530 - - - 0.6388 - 2.279 0.497 - 174.5 1 2 0 0.0008 16 0 0 0 1.49E+07 1.59E+06 - - - 4.7368 0.9966 221125_WJC_METTL3_EV_vs_WT_F09.08988.08988.3 0.0102 Dec-48 R.K[136.11]HTLSYVDVGTGK[136.11].V "sp|P31040|SDHA_HUMAN,tr|A0A087X1I3|A0A087X1I3_HUMAN,tr|D6RFM5|D6RFM5_HUMAN" 3 1419.7693 0.39 129231 8988 3 1419.773312 474.2637 "Succinate dehydrogenase [ubiquinone] flavoprotein subunit, mitochondrial OS=Homo sapiens OX=9606 GN=SDHA PE=1 SV=2" 8.51 1986.5 - 507057 - - - 2.8406 - 1.679 0.302 - 149.2 1 2 0 0.004 13 0 0 0 4.73E+06 1.22E+07 - - - 3.3109 0.9999 221125_WJC_METTL3_EV_vs_WT_F09.08991.08991.2 1.27E-06 28-Sep R.KLDYGQHVVAGTPGR.V "sp|P38919|IF4A3_HUMAN,tr|I3L3H2|I3L3H2_HUMAN" 2 1596.8372 1.77 129234 8991 2 1596.838303 799.4259 Eukaryotic initiation factor 4A-III OS=Homo sapiens OX=9606 GN=EIF4A3 PE=1 SV=4 8.6 1986.9 - 105255 - - - 0.6663 - 2.104 0.608 - 128.8 1 2 0 0.0011 15 0 0 0 1.84E+06 1.04E+06 - - - 5.3601 0.9995 221125_WJC_METTL3_EV_vs_WT_F09.08992.08992.2 1.27E-06 28-Sep R.K[136.11]LDYGQHVVAGTPGR[166.11].V "sp|P38919|IF4A3_HUMAN,tr|I3L3H2|I3L3H2_HUMAN" 2 1614.8597 1.77 129235 8992 2 1614.864415 808.4371 Eukaryotic initiation factor 4A-III OS=Homo sapiens OX=9606 GN=EIF4A3 PE=1 SV=4 8.6 1987 - 66699.1 - - - 2.9142 - 2.029 0.553 - 168 1 2 0 0.0047 15 0 0 0 1.84E+06 1.04E+06 - - - 4.8635 0.9959 221125_WJC_METTL3_EV_vs_WT_F09.08994.08994.3 1.16E-05 Oct-64 R.SSEEPTEK[136.11]EPPGQLQVK[136.11].A "sp|Q9ULV3|CIZ1_HUMAN,tr|Q5SYW2|Q5SYW2_HUMAN,tr|F5H2X7|F5H2X7_HUMAN,tr|H0Y5D5|H0Y5D5_HUMAN,tr|A0A494C0L7|A0A494C0L7_HUMAN,tr|Q9BTG3|Q9BTG3_HUMAN" 6 1897.9604 3.36 129236 8994 3 1897.969701 633.6607 Cip1-interacting zinc finger protein OS=Homo sapiens OX=9606 GN=CIZ1 PE=1 SV=2 4.49 1987.3 - 234748 - - - 4.9074 - 1.957 0.495 - 96.4 1 2 1 0.0093 17 0 0 0 1.08E+08 3.22E+07 - - - 5.7524 1 221125_WJC_METTL3_EV_vs_WT_F09.08997.08997.3 3.79E-08 Sep-60 K.TYTSTSNNSISGSLKR.L "sp|P55197|AF10_HUMAN,tr|Q5JT35|Q5JT35_HUMAN" 2 1714.8486 7.65 129238 8997 3 1714.8493 572.6235 Protein AF-10 OS=Homo sapiens OX=9606 GN=MLLT10 PE=1 SV=2 9.99 1987.6 - 255786 - - - 0.4129 - 1.97 0.586 - 61.3 1 2 0 0.0007 16 0 0 0 4.63E+06 6.06E+05 - - - 6.8129 0.9982 221125_WJC_METTL3_EV_vs_WT_F09.08999.08999.2 0.193 14-Aug K.VGEVIVTK.D "sp|P10809|CH60_HUMAN,tr|A0A7I2V2X6|A0A7I2V2X6_HUMAN,tr|A0A7I2YQK6|A0A7I2YQK6_HUMAN,tr|A0A7I2V599|A0A7I2V599_HUMAN" 4 843.5066 1.33 129240 8999 2 843.50701 422.7606 "60 kDa heat shock protein, mitochondrial OS=Homo sapiens OX=9606 GN=HSPD1 PE=1 SV=2" 5.97 1987.9 - 262713 - - - 0.5228 - 1.463 0.238 - 175.1 1 2 0 0.0004 8 0 0 0 6.16E+06 4.61E+06 - - - 1.9463 0.9999 221125_WJC_METTL3_EV_vs_WT_F09.09000.09000.3 1.45E-07 Dec-60 R.RGPQLVC[160.03]TGSDDGTVK.L sp|Q96DI7|SNR40_HUMAN 1 1688.8152 1.83 129241 9000 3 1688.819467 563.9457 U5 small nuclear ribonucleoprotein 40 kDa protein OS=Homo sapiens OX=9606 GN=SNRNP40 PE=1 SV=1 5.95 1988 - 240583 - - - 2.5367 - 2.125 0.56 - 199 1 2 0 0.0043 16 0 0 0 4.07E+06 2.22E+06 - - - 6.7163 0.9999 221125_WJC_METTL3_EV_vs_WT_F09.09005.09005.3 7.69E-09 16/64 R.SSEEPTEKEPPGQLQVK.A "sp|Q9ULV3|CIZ1_HUMAN,tr|Q5SYW2|Q5SYW2_HUMAN,tr|F5H2X7|F5H2X7_HUMAN,tr|H0Y5D5|H0Y5D5_HUMAN,tr|A0A494C0L7|A0A494C0L7_HUMAN,tr|Q9BTG3|Q9BTG3_HUMAN" 6 1881.932 3.36 129245 9005 3 1881.934404 628.3179 Cip1-interacting zinc finger protein OS=Homo sapiens OX=9606 GN=CIZ1 PE=1 SV=2 4.49 1988.6 - 488607 - - - 1.2843 - 3.187 0.583 - 238.2 1 2 1 0.0024 17 0 0 0 1.08E+08 3.22E+07 - - - 7.9674 1 221125_WJC_METTL3_EV_vs_WT_F09.09007.09007.3 1.16E-08 15/72 R.ILEQEEEEEQAGKPGEPSK.K sp|Q9BXP5|SRRT_HUMAN 1 2126.0015 1.27 129247 9007 3 2126.004973 709.6745 Serrate RNA effector molecule homolog OS=Homo sapiens OX=9606 GN=SRRT PE=1 SV=1 4.12 1988.9 - 150072 - - - 1.6228 - 3.178 0.631 - 242.6 1 2 0 0.0034 19 0 0 0 2.04E+06 1.61E+06 - - - 8.4148 0.9808 221125_WJC_METTL3_EV_vs_WT_F09.09014.09014.4 0.036 Dec-96 R.QGR[166.11]PVVIC[160.03]DK[136.11]EDTETIK[136.11].N "sp|Q06210|GFPT1_HUMAN,tr|A0A6I8PRN4|A0A6I8PRN4_HUMAN" 2 2013.0411 1.3 129252 9014 4 2013.045247 504.2676 Glutamine--fructose-6-phosphate aminotransferase [isomerizing] 1 OS=Homo sapiens OX=9606 GN=GFPT1 PE=1 SV=3 4.78 1989.8 - 512614 - - - 2.0546 - 1.911 0.248 - 99.1 1 2 1 0.0041 17 0 0 0 9.00E+07 6.91E+07 - - - 1.6083 0.9995 221125_WJC_METTL3_EV_vs_WT_F09.09016.09016.4 3.16E-07 14/96 R.QGRPVVIC[160.03]DKEDTETIK.N "sp|Q06210|GFPT1_HUMAN,tr|A0A6I8PRN4|A0A6I8PRN4_HUMAN" 2 1987.0044 1.3 129254 9016 4 1987.008665 497.7584 Glutamine--fructose-6-phosphate aminotransferase [isomerizing] 1 OS=Homo sapiens OX=9606 GN=GFPT1 PE=1 SV=3 4.78 1990.1 - 301602 - - - 2.1258 - 2.48 0.447 - 152.5 1 2 1 0.0042 17 0 0 0 9.00E+07 6.92E+07 - - - 3.4309 0.996 221125_WJC_METTL3_EV_vs_WT_F09.09021.09021.2 0.00327 28-May K.GSSPTPPC[160.03]SPVQPSK.Q "sp|Q9NUL3|STAU2_HUMAN,tr|E7EVJ4|E7EVJ4_HUMAN,tr|E7EPX0|E7EPX0_HUMAN,tr|H0YBY0|H0YBY0_HUMAN" 4 1524.7242 1.49 129259 9021 2 1524.727331 763.3694 Double-stranded RNA-binding protein Staufen homolog 2 OS=Homo sapiens OX=9606 GN=STAU2 PE=1 SV=2 8.22 1990.7 - 112648 - - - 2.0253 - 0.987 0.393 - 40 1 2 0 0.0031 15 0 0 0 1.36E+07 9.15E+06 - - - 1.9106 1 221125_WJC_METTL3_EV_vs_WT_F09.09025.09025.3 1.04E-10 21/56 R.TPTQTNGSNVPFK[136.11]PR[166.11].G "sp|P78347|GTF2I_HUMAN,tr|A0A494C1K3|A0A494C1K3_HUMAN" 2 1660.8652 1.56 129261 9025 3 1660.866842 554.629 General transcription factor II-I OS=Homo sapiens OX=9606 GN=GTF2I PE=1 SV=2 11 1991.3 - 1.21E+06 - - - 0.9959 - 3.534 0.677 - 395.9 1 2 0 0.0017 15 0 0 0 2.95E+09 1.89E+09 - - - 9.3816 1 221125_WJC_METTL3_EV_vs_WT_F09.09026.09026.3 1.48E-07 23/56 R.TPTQTNGSNVPFKPR.G "sp|P78347|GTF2I_HUMAN,tr|A0A494C1K3|A0A494C1K3_HUMAN" 2 1642.8427 1.56 129262 9026 3 1642.846126 548.6215 General transcription factor II-I OS=Homo sapiens OX=9606 GN=GTF2I PE=1 SV=2 11 1991.4 - 1.26E+06 - - - 2.0745 - 3.667 0.565 - 509.3 1 2 0 0.0034 15 0 0 0 2.94E+09 1.88E+09 - - - 8.2288 0.9873 221125_WJC_METTL3_EV_vs_WT_F09.09028.09028.2 2.02 May-32 K.GQGSVSASVTEGQQNEQ.- sp|P55735|SEC13_HUMAN 1 1704.7551 - 129264 9028 2 1704.755927 853.3848 Protein SEC13 homolog OS=Homo sapiens OX=9606 GN=SEC13 PE=1 SV=3 3.79 1991.6 - 192469 - - - 0.4939 - 1.02 0.193 - 52.7 1 2 0 0.0008 17 0 0 0 - - - - - 0.5149 1 221125_WJC_METTL3_EV_vs_WT_F09.09033.09033.3 7.86E-11 22/64 R.QGRPVVIC[160.03]DKEDTETIK.N "sp|Q06210|GFPT1_HUMAN,tr|A0A6I8PRN4|A0A6I8PRN4_HUMAN" 2 1987.0044 1.76 129267 9033 3 1987.000939 663.3421 Glutamine--fructose-6-phosphate aminotransferase [isomerizing] 1 OS=Homo sapiens OX=9606 GN=GFPT1 PE=1 SV=3 4.78 1992.3 - 281710 - - - -1.7625 - 3.792 0.652 - 640 1 2 1 -0.0035 17 0 0 0 3.92E+07 2.23E+07 - - - 9.1755 0.9996 221125_WJC_METTL3_EV_vs_WT_F09.09034.09034.3 4.87E-06 Oct-60 R.SK[136.11]DTC[160.03]IVISGESGAGK[136.11].T "sp|O94832|MYO1D_HUMAN,tr|K7EIG7|K7EIG7_HUMAN,tr|J3KRL0|J3KRL0_HUMAN,tr|J3QRN6|J3QRN6_HUMAN" 4 1623.8109 0.6 129268 9034 3 1623.813606 542.2776 Unconventional myosin-Id OS=Homo sapiens OX=9606 GN=MYO1D PE=1 SV=2 5.79 1992.4 - 129094 - - - 1.6751 - 1.95 0.499 - 119.9 1 2 1 0.0027 16 0 0 0 1.32E+06 2.18E+06 - - - 5.8162 0.9992 221125_WJC_METTL3_EV_vs_WT_F09.09038.09038.3 0.00349 Sep-44 R.RTEEGPTLSYGR.D "sp|P43243|MATR3_HUMAN,tr|A8MXP9|A8MXP9_HUMAN,tr|D6R991|D6R991_HUMAN,tr|A0A0R4J2E8|A0A0R4J2E8_HUMAN,tr|D6REM6|D6REM6_HUMAN" 5 1364.6684 1.38 129270 9038 3 1364.671758 455.8968 Matrin-3 OS=Homo sapiens OX=9606 GN=MATR3 PE=1 SV=2 6.14 1993 - 292748 - - - 2.4299 - 1.824 0.356 - 154.2 1 2 0 0.0033 12 0 0 0 5.27E+07 3.81E+07 - - - 4.1741 0.9999 221125_WJC_METTL3_EV_vs_WT_F09.09040.09040.3 5.87E-05 Nov-44 R.R[166.11]TEEGPTLSYGR[166.11].D "sp|P43243|MATR3_HUMAN,tr|A8MXP9|A8MXP9_HUMAN,tr|D6R991|D6R991_HUMAN,tr|A0A0R4J2E8|A0A0R4J2E8_HUMAN,tr|D6REM6|D6REM6_HUMAN" 5 1384.685 1.38 129272 9040 3 1384.68758 462.5689 Matrin-3 OS=Homo sapiens OX=9606 GN=MATR3 PE=1 SV=2 6.14 1993.2 - 285412 - - - 1.8762 - 2.153 0.424 - 212.2 1 2 0 0.0026 12 0 0 0 5.27E+07 3.81E+07 - - - 5.3921 1 221125_WJC_METTL3_EV_vs_WT_F09.09048.09048.2 1.95E-07 28-Dec R.TPTQTNGSNVPFK[136.11]PR[166.11].G "sp|P78347|GTF2I_HUMAN,tr|A0A494C1K3|A0A494C1K3_HUMAN" 2 1660.8652 1.56 129278 9048 2 1660.866642 831.4399 General transcription factor II-I OS=Homo sapiens OX=9606 GN=GTF2I PE=1 SV=2 11 1994.3 - 91804.5 - - - 0.8754 - 2.759 0.691 - 429.2 1 2 0 0.0015 15 0 0 0 7.93E+07 5.08E+07 - - - 6.6394 1 221125_WJC_METTL3_EV_vs_WT_F09.09053.09053.2 4.63E-09 28-Nov R.TPTQTNGSNVPFKPR.G "sp|P78347|GTF2I_HUMAN,tr|A0A494C1K3|A0A494C1K3_HUMAN" 2 1642.8427 1.56 129281 9053 2 1642.842768 822.4286 General transcription factor II-I OS=Homo sapiens OX=9606 GN=GTF2I PE=1 SV=2 11 1995 - 172456 - - - 0.0304 - 2.444 0.673 - 325 1 2 0 0.0001 15 0 0 0 7.93E+07 5.08E+07 - - - 6.2088 1 221125_WJC_METTL3_EV_vs_WT_F09.09061.09061.3 4.95E-09 14/52 K.K[136.11]GPGEVAGTVTGQK[136.11].R "sp|Q86U44|MTA70_HUMAN,tr|F5H6D8|F5H6D8_HUMAN,tr|H0YFV6|H0YFV6_HUMAN,tr|B4DTN4|B4DTN4_HUMAN" 4 1343.738 0.01 129286 9061 3 1343.739209 448.9199 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 8.59 1996 - 411906 - - - 0.9154 - 2.818 0.533 - 334.7 1 2 0 0.0012 14 0 0 0 4.91E+05 4.03E+07 - - - 7.2354 0.9997 221125_WJC_METTL3_EV_vs_WT_F09.09077.09077.3 0.000456 Sep-56 R.TPTQTNGSNVPFKPR[166.11].G "sp|P78347|GTF2I_HUMAN,tr|A0A494C1K3|A0A494C1K3_HUMAN" 2 1652.851 - 129296 9077 3 1652.851112 551.9576 General transcription factor II-I OS=Homo sapiens OX=9606 GN=GTF2I PE=1 SV=2 11 1998 - 370811 - - - 0.075 - 1.836 0.37 - 91.5 1 2 0 0.0001 15 0 0 0 - - - - - 4.2505 0.9999 221125_WJC_METTL3_EV_vs_WT_F09.09084.09084.4 0.000215 Sep-72 K.RTNAENEFVTIKK.D sp|P04264|K2C1_HUMAN 1 1548.826 23.47 129301 9084 4 1548.828582 388.2138 "Keratin, type II cytoskeletal 1 OS=Homo sapiens OX=9606 GN=KRT1 PE=1 SV=6" 8.59 1998.9 - 118432 - - - 1.6632 - 1.658 0.426 - 85.7 1 2 0 0.0026 13 0 0 0 1.86E+07 7.94E+05 - - - 3.1207 0.9984 221125_WJC_METTL3_EV_vs_WT_F09.09092.09092.4 0.0208 Nov-84 R.TPTQTNGSNVPFKPR.G "sp|P78347|GTF2I_HUMAN,tr|A0A494C1K3|A0A494C1K3_HUMAN" 2 1642.8427 1.43 129304 9092 4 1642.841983 411.718 General transcription factor II-I OS=Homo sapiens OX=9606 GN=GTF2I PE=1 SV=2 11 1999.9 - 367743 - - - -0.4474 - 1.731 0.28 - 89.4 1 2 0 -0.0007 15 0 0 0 1.86E+07 1.30E+07 - - - 1.8592 0.9999 221125_WJC_METTL3_EV_vs_WT_F09.09108.09108.4 0.000296 Dec-90 R.SFGTEDR[166.11]PTDR[166.11]PIPPR[166.11].D "sp|Q8ND56|LS14A_HUMAN,tr|I3L4Q1|I3L4Q1_HUMAN,tr|A0A140TA76|A0A140TA76_HUMAN,tr|K7EMZ9|K7EMZ9_HUMAN" 4 1869.9476 0.97 129310 9108 4 1869.946427 468.4942 Protein LSM14 homolog A OS=Homo sapiens OX=9606 GN=LSM14A PE=1 SV=3 5.84 2002.2 - 208053 - - - -0.6112 - 2.033 0.447 - 86.9 1 2 0 -0.0011 16 0 0 0 2.45E+07 2.53E+07 - - - 3.3663 0.9997 221125_WJC_METTL3_EV_vs_WT_F09.09123.09123.4 0.019 Sep-84 K.K[136.11]PPLLDR[166.11]PGEGSYNR[166.11].Y "sp|Q8NEY8|PPHLN_HUMAN,tr|F8VRK2|F8VRK2_HUMAN,tr|F8VWU8|F8VWU8_HUMAN,tr|F8W0Q9|F8W0Q9_HUMAN,tr|F8VPY7|F8VPY7_HUMAN" 5 1725.9157 1.8 129317 9123 4 1725.914894 432.4862 Periphilin-1 OS=Homo sapiens OX=9606 GN=PPHLN1 PE=1 SV=2 8.59 2004.1 - 162911 - - - -0.4427 - 1.853 0.357 - 48.6 1 2 0 -0.0008 15 0 0 0 1.28E+07 7.14E+06 - - - 2.5538 0.9998 221125_WJC_METTL3_EV_vs_WT_F09.09130.09130.3 0.0344 Dec-68 K.NKPGPYSSVPPPSAPPPK.K "sp|Q14978|NOLC1_HUMAN,tr|A0A0A0MRM9|A0A0A0MRM9_HUMAN,tr|S4R349|S4R349_HUMAN" 3 1815.9519 2.57 129321 9130 3 1815.94937 606.3246 Nucleolar and coiled-body phosphoprotein 1 OS=Homo sapiens OX=9606 GN=NOLC1 PE=1 SV=2 9.7 2004.9 - 1.05E+06 - - - -1.4125 - 2.521 0.365 - 210.7 1 2 0 -0.0026 18 0 0 0 9.14E+07 3.56E+07 - - - 4.9112 1 221125_WJC_METTL3_EV_vs_WT_F09.09133.09133.3 9.34E-08 13/48 K.RTNAENEFVTIKK.D sp|P04264|K2C1_HUMAN 1 1548.826 963.7 129322 9133 3 1548.825865 517.2826 "Keratin, type II cytoskeletal 1 OS=Homo sapiens OX=9606 GN=KRT1 PE=1 SV=6" 8.59 2005.5 - 998369 - - - -0.091 - 2.617 0.569 - 273.7 1 2 0 -0.0001 13 0 0 0 4.10E+07 4.25E+04 - - - 7.4921 0.9996 221125_WJC_METTL3_EV_vs_WT_F09.09135.09135.4 0.0009 13/90 R.SFGTEDRPTDRPIPPR.D "sp|Q8ND56|LS14A_HUMAN,tr|I3L4Q1|I3L4Q1_HUMAN,tr|A0A140TA76|A0A140TA76_HUMAN,tr|K7EMZ9|K7EMZ9_HUMAN" 4 1839.9228 0.97 129323 9135 4 1839.921021 460.988 Protein LSM14 homolog A OS=Homo sapiens OX=9606 GN=LSM14A PE=1 SV=3 5.84 2005.7 - 486843 - - - -0.9451 - 1.953 0.341 - 107.7 1 2 0 -0.0017 16 0 0 0 2.42E+07 2.50E+07 - - - 2.4294 0.9986 221125_WJC_METTL3_EV_vs_WT_F09.09137.09137.3 0.0825 Oct-56 K.K[136.11]PPLLDR[166.11]PGEGSYNR[166.11].Y "sp|Q8NEY8|PPHLN_HUMAN,tr|F8VRK2|F8VRK2_HUMAN,tr|F8VWU8|F8VWU8_HUMAN,tr|F8W0Q9|F8W0Q9_HUMAN,tr|F8VPY7|F8VPY7_HUMAN" 5 1725.9157 1.91 129325 9137 3 1725.914786 576.3125 Periphilin-1 OS=Homo sapiens OX=9606 GN=PPHLN1 PE=1 SV=2 8.59 2005.9 - 384267 - - - -0.5052 - 1.641 0.29 - 110.3 1 2 0 -0.0009 15 0 0 0 1.92E+07 1.01E+07 - - - 3.0654 0.9998 221125_WJC_METTL3_EV_vs_WT_F09.09138.09138.2 0.000127 28-Aug K.QGGGGGGGSVPGIER.M "sp|P52272|HNRPM_HUMAN,tr|M0R019|M0R019_HUMAN,tr|A0A087X0X3|A0A087X0X3_HUMAN,tr|M0R2T0|M0R2T0_HUMAN" 4 1283.6218 2.95 129326 9138 2 1283.621344 642.8182 Heterogeneous nuclear ribonucleoprotein M OS=Homo sapiens OX=9606 GN=HNRNPM PE=1 SV=3 6 2006.1 - 173635 - - - -0.3763 - 1.838 0.535 - 128.5 1 2 0 -0.0005 15 0 0 0 5.64E+06 1.91E+06 - - - 4.4888 0.9999 221125_WJC_METTL3_EV_vs_WT_F09.09145.09145.2 4.98E-06 Jun-32 K.AGYSQGATQYTQAQQTR.Q sp|Q96KR1|ZFR_HUMAN 1 1857.8606 1.29 129330 9145 2 1857.858184 929.9376 Zinc finger RNA-binding protein OS=Homo sapiens OX=9606 GN=ZFR PE=1 SV=2 8.63 2006.9 - 102134 - - - -1.2751 - 1.9 0.674 - 76.3 1 2 0 -0.0024 17 0 0 0 2.92E+06 2.27E+06 - - - 5.5964 0.9998 221125_WJC_METTL3_EV_vs_WT_F09.09148.09148.3 0.00175 Nov-68 K.NK[136.11]PGPYSSVPPPSAPPPK[136.11].K "sp|Q14978|NOLC1_HUMAN,tr|A0A0A0MRM9|A0A0A0MRM9_HUMAN,tr|S4R349|S4R349_HUMAN" 3 1831.9803 2.57 129331 9148 3 1831.981289 611.6674 Nucleolar and coiled-body phosphoprotein 1 OS=Homo sapiens OX=9606 GN=NOLC1 PE=1 SV=2 9.7 2007.4 - 367721 - - - 0.5207 - 2.043 0.372 - 129.5 1 2 0 0.001 18 0 0 0 9.00E+07 3.51E+07 - - - 4.4661 0.9992 221125_WJC_METTL3_EV_vs_WT_F09.09149.09149.3 0.00309 Sep-60 R.SFGTEDRPTDRPIPPR.D "sp|Q8ND56|LS14A_HUMAN,tr|I3L4Q1|I3L4Q1_HUMAN,tr|A0A140TA76|A0A140TA76_HUMAN,tr|K7EMZ9|K7EMZ9_HUMAN" 4 1839.9228 1.11 129332 9149 3 1839.922163 614.3149 Protein LSM14 homolog A OS=Homo sapiens OX=9606 GN=LSM14A PE=1 SV=3 5.84 2007.5 - 329521 - - - -0.3245 - 1.574 0.338 - 42.2 1 2 0 -0.0006 16 0 0 0 1.08E+07 9.76E+06 - - - 3.4721 0.9985 221125_WJC_METTL3_EV_vs_WT_F09.09150.09150.3 0.000556 Sep-44 K.K[136.11]DEDPENK[136.11]IEFK[136.11].T "sp|Q13123|RED_HUMAN,tr|D6REL4|D6REL4_HUMAN,tr|E7EQZ7|E7EQZ7_HUMAN" 3 1514.7679 1.63 129333 9150 3 1514.764416 505.9299 Protein Red OS=Homo sapiens OX=9606 GN=IK PE=1 SV=3 4.51 2007.6 - 241779 - - - -2.2928 - 1.483 0.466 - 121.5 1 2 1 -0.0035 12 0 0 0 8.31E+06 5.11E+06 - - - 4.8268 0.9606 221125_WJC_METTL3_EV_vs_WT_F09.09155.09155.3 0.284 Sep-60 R.SFGTEDR[166.11]PTDR[166.11]PIPPR[166.11].D "sp|Q8ND56|LS14A_HUMAN,tr|I3L4Q1|I3L4Q1_HUMAN,tr|A0A140TA76|A0A140TA76_HUMAN,tr|K7EMZ9|K7EMZ9_HUMAN" 4 1869.9476 1.1 129336 9155 3 1869.9478 624.3231 Protein LSM14 homolog A OS=Homo sapiens OX=9606 GN=LSM14A PE=1 SV=3 5.84 2008.3 - 317828 - - - 0.123 - 1.196 0.179 - 40.4 1 2 0 0.0002 16 0 0 0 1.08E+07 9.89E+06 - - - 0.9949 1 221125_WJC_METTL3_EV_vs_WT_F09.09159.09159.2 2.51E-10 Dec-32 K.AGYSQGATQYTQAQQTR[166.11].Q sp|Q96KR1|ZFR_HUMAN 1 1867.8688 1.29 129340 9159 2 1867.869686 934.9417 Zinc finger RNA-binding protein OS=Homo sapiens OX=9606 GN=ZFR PE=1 SV=2 8.63 2008.8 - 107631 - - - 0.462 - 2.96 0.749 - 453.9 1 2 0 0.0009 17 0 0 0 2.92E+06 2.27E+06 - - - 7.2408 0.9993 221125_WJC_METTL3_EV_vs_WT_F09.09163.09163.3 0.000342 Sep-44 K.KDEDPENKIEFK.T "sp|Q13123|RED_HUMAN,tr|D6REL4|D6REL4_HUMAN,tr|E7EQZ7|E7EQZ7_HUMAN" 3 1490.7253 1.4 129342 9163 3 1490.724902 497.9157 Protein Red OS=Homo sapiens OX=9606 GN=IK PE=1 SV=3 4.51 2009.4 - 298299 - - - -0.2596 - 1.725 0.422 - 119.6 1 2 1 -0.0004 12 0 0 0 8.45E+06 6.02E+06 - - - 4.7561 0.999 221125_WJC_METTL3_EV_vs_WT_F09.09165.09165.3 3.60E-06 14/60 K.AIK[136.11]VEQATK[136.11]PSFESGR[166.11].R "sp|P38159|RBMX_HUMAN,tr|H3BT71|H3BT71_HUMAN,tr|H0Y6E7|H0Y6E7_HUMAN" 3 1772.9631 1.45 129344 9165 3 1772.970155 591.995 "RNA-binding motif protein, X chromosome OS=Homo sapiens OX=9606 GN=RBMX PE=1 SV=3" 8.63 2009.6 - 173306 - - - 3.9691 - 2.356 0.521 - 152.7 1 2 1 0.007 16 0 0 0 1.76E+07 1.21E+07 - - - 6.5455 0.9999 221125_WJC_METTL3_EV_vs_WT_F09.09169.09169.4 4.67E-10 16/90 K.AIKVEQATKPSFESGR.R "sp|P38159|RBMX_HUMAN,tr|H3BT71|H3BT71_HUMAN,tr|H0Y6E7|H0Y6E7_HUMAN" 3 1746.9264 1.32 129346 9169 4 1746.928859 437.7389 "RNA-binding motif protein, X chromosome OS=Homo sapiens OX=9606 GN=RBMX PE=1 SV=3" 8.63 2010.1 - 731737 - - - 1.3801 - 2.968 0.515 - 136 1 2 1 0.0024 16 0 0 0 3.18E+07 2.40E+07 - - - 4.0911 0.9999 221125_WJC_METTL3_EV_vs_WT_F09.09170.09170.3 3.46E-08 15/60 K.AIKVEQATKPSFESGR.R "sp|P38159|RBMX_HUMAN,tr|H3BT71|H3BT71_HUMAN,tr|H0Y6E7|H0Y6E7_HUMAN" 3 1746.9264 1.39 129347 9170 3 1746.927438 583.3161 "RNA-binding motif protein, X chromosome OS=Homo sapiens OX=9606 GN=RBMX PE=1 SV=3" 8.63 2010.3 - 323532 - - - 0.5667 - 2.985 0.575 - 159.9 1 2 1 0.001 16 0 0 0 1.69E+07 1.21E+07 - - - 7.7564 1 221125_WJC_METTL3_EV_vs_WT_F09.09178.09178.4 1.46E-08 17/90 K.AIK[136.11]VEQATK[136.11]PSFESGR[166.11].R "sp|P38159|RBMX_HUMAN,tr|H3BT71|H3BT71_HUMAN,tr|H0Y6E7|H0Y6E7_HUMAN" 3 1772.9631 1.32 129351 9178 4 1772.965461 444.2481 "RNA-binding motif protein, X chromosome OS=Homo sapiens OX=9606 GN=RBMX PE=1 SV=3" 8.63 2011.3 - 1.34E+06 - - - 1.3215 - 2.863 0.637 - 143.5 1 2 1 0.0023 16 0 0 0 3.18E+07 2.40E+07 - - - 5.1403 1 221125_WJC_METTL3_EV_vs_WT_F09.09179.09179.4 1.57E-06 20/96 K.VEEKPPPAPSIATKPVR.T "sp|Q9Y520|PRC2C_HUMAN,tr|E7EPN9|E7EPN9_HUMAN,tr|H7C5N8|H7C5N8_HUMAN,tr|A0A2R8YET2|A0A2R8YET2_HUMAN" 4 1815.0254 3.41 129352 9179 4 1815.028619 454.7636 Protein PRRC2C OS=Homo sapiens OX=9606 GN=PRRC2C PE=1 SV=4 8.56 2011.5 - 301150 - - - 1.7548 - 3.147 0.551 - 333.9 1 2 0 0.0032 17 0 0 0 4.21E+06 1.23E+06 - - - 4.4191 0.9999 221125_WJC_METTL3_EV_vs_WT_F09.09181.09181.3 4.85E-07 Nov-76 K.VDNALQSGNSQESVTEQDSK.D "sp|P01834|IGKC_HUMAN,tr|A0A5H1ZRQ3|A0A5H1ZRQ3_HUMAN" 2 2134.9614 21.93 129354 9181 3 2134.970108 712.6611 Immunoglobulin kappa constant OS=Homo sapiens OX=9606 GN=IGKC PE=1 SV=2 3.92 2011.7 - 177599 - - - 4.0558 - 2.607 0.589 - 128.7 1 2 0 0.0087 20 0 0 0 1.54E+07 7.03E+05 - - - 7.429 0.9986 221125_WJC_METTL3_EV_vs_WT_F09.09187.09187.3 0.0105 Sep-52 K.GIGTLHLK[136.11]PTANQK[136.11].T "sp|Q9UKX7|NUP50_HUMAN,tr|B0QY21|B0QY21_HUMAN" 2 1492.8697 0.001 129358 9187 3 1492.869869 498.6305 Nuclear pore complex protein Nup50 OS=Homo sapiens OX=9606 GN=NUP50 PE=1 SV=2 10 2012.5 - 206205 - - - 0.1387 - 1.505 0.311 - 54.7 1 2 0 0.0002 14 0 0 0 0.00E+00 3.90E+06 - - - 3.0937 0.9999 221125_WJC_METTL3_EV_vs_WT_F09.09188.09188.3 6.60E-06 Nov-80 R.SLQEEQSR[166.11]PPTAVSSPGGPAR[166.11].A "sp|Q9BWU0|NADAP_HUMAN,tr|A0A087X0M4|A0A087X0M4_HUMAN" 2 2170.0881 0.96 129359 9188 3 2170.088561 724.37 Kanadaptin OS=Homo sapiens OX=9606 GN=SLC4A1AP PE=1 SV=1 5.86 2012.7 - 89684.7 - - - 0.1899 - 2.635 0.412 - 97.5 1 2 0 0.0004 21 0 0 0 1.54E+06 1.59E+06 - - - 5.4561 1 221125_WJC_METTL3_EV_vs_WT_F09.09191.09191.3 1.75E-07 22/52 R.K[136.11]NPLPPSVGVVDK[136.11]K[136.11].E sp|Q8NC51|PAIRB_HUMAN 1 1500.909 0.81 129361 9191 3 1500.912658 501.3103 Plasminogen activator inhibitor 1 RNA-binding protein OS=Homo sapiens OX=9606 GN=SERBP1 PE=1 SV=2 9.7 2013.1 - 1.53E+06 - - - 2.4279 - 3.909 0.632 - 821 1 2 0 0.0036 14 0 0 0 7.30E+07 9.00E+07 - - - 9.2081 0.9982 221125_WJC_METTL3_EV_vs_WT_F09.09199.09199.3 0.021 Jun-52 K.HEAFESDLAAHQDR.V "sp|O43707|ACTN4_HUMAN,sp|Q08043|ACTN3_HUMAN,sp|P35609|ACTN2_HUMAN,sp|P12814|ACTN1_HUMAN,tr|A0A804HK61|A0A804HK61_HUMAN,tr|H7C5W8|H7C5W8_HUMAN,tr|A0A804HJU8|A0A804HJU8_HUMAN,tr|A0A804HIN7|A0A804HIN7_HUMAN,tr|A0A494C060|A0A494C060_HUMAN,tr|H9KV75|H9KV75_HUMAN,tr|A0A087WSZ2|A0A087WSZ2_HUMAN,tr|A0A804HLF4|A0A804HLF4_HUMAN,tr|A0A7I2V4Y4|A0A7I2V4Y4_HUMAN,tr|A0A804HII9|A0A804HII9_HUMAN,tr|A0A804HL31|A0A804HL31_HUMAN,tr|A0A494C1A0|A0A494C1A0_HUMAN,tr|F5GXS2|F5GXS2_HUMAN,tr|A0A804HI95|A0A804HI95_HUMAN,tr|A0A804HKE2|A0A804HKE2_HUMAN,tr|A0A804HLD0|A0A804HLD0_HUMAN,tr|H7C144|H7C144_HUMAN" 21 1624.723 1.07 129367 9199 3 1624.72296 542.5816 Alpha-actinin-4 OS=Homo sapiens OX=9606 GN=ACTN4 PE=1 SV=2 4.72 2014.1 - 95070.3 - - - -0.0228 - 1.329 0.324 - 34.3 1 2 0 0 14 0 0 0 2.09E+06 1.96E+06 - - - 2.9081 1 221125_WJC_METTL3_EV_vs_WT_F09.09206.09206.3 8.00E-07 22/52 R.KNPLPPSVGVVDKK.E sp|Q8NC51|PAIRB_HUMAN 1 1476.8664 0.81 129373 9206 3 1476.870039 493.2961 Plasminogen activator inhibitor 1 RNA-binding protein OS=Homo sapiens OX=9606 GN=SERBP1 PE=1 SV=2 9.7 2015 - 1.10E+06 - - - 2.4545 - 3.797 0.64 - 806.5 1 2 0 0.0036 14 0 0 0 7.30E+07 9.00E+07 - - - 9.2201 0.9996 221125_WJC_METTL3_EV_vs_WT_F09.09209.09209.4 0.000333 Dec-90 K.AGVENGK[136.11]PTHFTVYTK[136.11].G "sp|O75369|FLNB_HUMAN,tr|E7EN95|E7EN95_HUMAN,tr|A0A804HK76|A0A804HK76_HUMAN,tr|A0A804HL72|A0A804HL72_HUMAN" 4 1763.9177 0.63 129375 9209 4 1763.923236 441.9867 Filamin-B OS=Homo sapiens OX=9606 GN=FLNB PE=1 SV=2 8.55 2015.4 - 530084 - - - 3.1192 - 2.142 0.415 - 87.9 1 2 0 0.0055 16 0 0 0 4.46E+06 7.05E+06 - - - 3.105 1 221125_WJC_METTL3_EV_vs_WT_F09.09210.09210.3 4.69E-05 13/60 R.NSATSADEQPHIGNYR.L "sp|Q7KZI7|MARK2_HUMAN,tr|F5H6N2|F5H6N2_HUMAN,tr|A0A0A0MRU9|A0A0A0MRU9_HUMAN,tr|E7ETY4|E7ETY4_HUMAN,tr|F5H4F6|F5H4F6_HUMAN,tr|A0A7I2YQR3|A0A7I2YQR3_HUMAN,tr|E9PC69|E9PC69_HUMAN,tr|A0A7I2V3R3|A0A7I2V3R3_HUMAN,tr|F5H4J8|F5H4J8_HUMAN" 9 1758.7921 0.97 129376 9210 3 1758.79542 587.2713 Serine\threonine-protein kinase MARK2 OS=Homo sapiens OX=9606 GN=MARK2 PE=1 SV=2 5.32 2015.5 - 361040 - - - 1.8655 - 3.183 0.504 - 163.8 1 2 0 0.0033 16 0 0 0 1.75E+07 1.80E+07 - - - 7.129 0.9036 221125_WJC_METTL3_EV_vs_WT_F09.09212.09212.4 0.0466 Jul-78 K.VVHLGDKEQSNWAK.E "sp|Q8IZH2|XRN1_HUMAN,tr|H7C5E4|H7C5E4_HUMAN" 2 1609.8213 1.57 129378 9212 4 1609.825384 403.4626 5'-3' exoribonuclease 1 OS=Homo sapiens OX=9606 GN=XRN1 PE=1 SV=1 6.72 2015.8 - 168957 - - - 2.5649 - 1.415 0.203 - 38.2 1 2 1 0.0041 14 0 0 0 3.71E+06 2.37E+06 - - - 1.1181 0.8973 221125_WJC_METTL3_EV_vs_WT_F09.09225.09225.4 0.0316 Sep-90 K.AGVENGKPTHFTVYTK.G "sp|O75369|FLNB_HUMAN,tr|E7EN95|E7EN95_HUMAN,tr|A0A804HK76|A0A804HK76_HUMAN,tr|A0A804HL72|A0A804HL72_HUMAN" 4 1747.8893 0.63 129389 9225 4 1747.890215 437.9796 Filamin-B OS=Homo sapiens OX=9606 GN=FLNB PE=1 SV=2 8.55 2017.6 - 478054 - - - 0.504 - 1.735 0.11 - 24.8 1 2 0 0.0009 16 0 0 0 4.41E+06 7.00E+06 - - - 0.3773 0.9998 221125_WJC_METTL3_EV_vs_WT_F09.09226.09226.3 0.000515 13/64 R.LEK[136.11]PETQSSPITVQSSK[136.11].D "sp|Q96CB8|INT12_HUMAN,tr|A0A087WXN4|A0A087WXN4_HUMAN,tr|E9PGI3|E9PGI3_HUMAN" 3 1873.9968 1.32 129390 9226 3 1874.000872 625.6729 Integrator complex subunit 12 OS=Homo sapiens OX=9606 GN=INTS12 PE=1 SV=1 6.14 2017.7 - 427157 - - - 2.1873 - 2.104 0.459 - 206.2 1 2 0 0.0041 17 0 0 0 1.46E+08 1.10E+08 - - - 5.5354 0.9782 221125_WJC_METTL3_EV_vs_WT_F09.09227.09227.3 0.0003 Oct-56 F.SQPPAPPHQNTFPPR.S sp|Q96I24|FUBP3_HUMAN 1 1669.8325 3.15 129391 9227 3 1669.835893 557.6181 Far upstream element-binding protein 3 OS=Homo sapiens OX=9606 GN=FUBP3 PE=1 SV=2 9.49 2017.8 - 205631 - - - 2.0391 - 2.218 0.405 - 100.1 1 1 0 0.0034 15 0 0 0 9.45E+06 3.00E+06 - - - 5.133 0.8518 221125_WJC_METTL3_EV_vs_WT_F09.09228.09228.3 0.00804 Oct-48 L.R[166.11]DNIQGITK[136.11]PAIR[166.11].R sp|P62805|H4_HUMAN 1 1508.8782 1.21 129392 9228 3 1508.881374 503.9667 Histone H4 OS=Homo sapiens OX=9606 GN=H4C1 PE=1 SV=2 10.84 2017.9 - 155438 - - - 2.1367 - 1.639 0.324 - 132.2 1 1 0 0.0032 13 0 0 0 1.28E+07 1.06E+07 - - - 3.491 1 221125_WJC_METTL3_EV_vs_WT_F09.09233.09233.3 7.49E-08 21/60 R.NSATSADEQPHIGNYR[166.11].L "sp|Q7KZI7|MARK2_HUMAN,tr|F5H6N2|F5H6N2_HUMAN,tr|A0A0A0MRU9|A0A0A0MRU9_HUMAN,tr|E7ETY4|E7ETY4_HUMAN,tr|F5H4F6|F5H4F6_HUMAN,tr|A0A7I2YQR3|A0A7I2YQR3_HUMAN,tr|E9PC69|E9PC69_HUMAN,tr|A0A7I2V3R3|A0A7I2V3R3_HUMAN,tr|F5H4J8|F5H4J8_HUMAN" 9 1768.8004 0.97 129395 9233 3 1768.804451 590.6074 Serine\threonine-protein kinase MARK2 OS=Homo sapiens OX=9606 GN=MARK2 PE=1 SV=2 5.32 2018.6 - 1.06E+06 - - - 2.2852 - 4.092 0.674 - 587.2 1 2 0 0.004 16 0 0 0 1.75E+07 1.80E+07 - - - 9.6687 0.9999 221125_WJC_METTL3_EV_vs_WT_F09.09234.09234.4 0.000352 Dec-96 K.VEEK[136.11]PPPAPSIATK[136.11]PVR[166.11].T "sp|Q9Y520|PRC2C_HUMAN,tr|E7EPN9|E7EPN9_HUMAN,tr|H7C5N8|H7C5N8_HUMAN,tr|A0A2R8YET2|A0A2R8YET2_HUMAN" 4 1841.0621 2.44 129396 9234 4 1841.064473 461.2728 Protein PRRC2C OS=Homo sapiens OX=9606 GN=PRRC2C PE=1 SV=4 8.56 2018.7 - 352041 - - - 1.2868 - 1.903 0.47 - 51.7 1 2 0 0.0024 17 0 0 0 8.45E+07 3.47E+07 - - - 3.5396 0.9997 221125_WJC_METTL3_EV_vs_WT_F09.09237.09237.3 0.00445 Nov-60 K.AGVENGKPTHFTVYTK.G "sp|O75369|FLNB_HUMAN,tr|E7EN95|E7EN95_HUMAN,tr|A0A804HK76|A0A804HK76_HUMAN,tr|A0A804HL72|A0A804HL72_HUMAN" 4 1747.8893 0.62 129399 9237 3 1747.892522 583.6371 Filamin-B OS=Homo sapiens OX=9606 GN=FLNB PE=1 SV=2 8.55 2019.1 - 229628 - - - 1.8239 - 1.898 0.398 - 85.1 1 2 0 0.0032 16 0 0 0 1.86E+06 3.00E+06 - - - 4.6206 1 221125_WJC_METTL3_EV_vs_WT_F09.09238.09238.2 3.83E-09 Dec-38 K.VDNALQSGNSQESVTEQDSK.D "sp|P01834|IGKC_HUMAN,tr|A0A5H1ZRQ3|A0A5H1ZRQ3_HUMAN" 2 2134.9614 999 129400 9238 2 2134.969618 1068.488 Immunoglobulin kappa constant OS=Homo sapiens OX=9606 GN=IGKC PE=1 SV=2 3.92 2019.2 - 169822 - - - 3.8263 - 2.815 0.679 - 322.2 1 2 0 0.0082 20 0 0 0 2.74E+06 0.00E+00 - - - 6.598 0.9929 221125_WJC_METTL3_EV_vs_WT_F09.09244.09244.3 9.67E-05 Sep-64 K.SAVSTSVPTKPTENISK.A sp|Q5VT52|RPRD2_HUMAN 1 1744.9207 1.88 129404 9244 3 1744.926553 582.6475 Regulation of nuclear pre-mRNA domain-containing protein 2 OS=Homo sapiens OX=9606 GN=RPRD2 PE=1 SV=1 8.31 2020 - 196760 - - - 3.3577 - 1.957 0.253 - 94.1 1 2 0 0.0059 17 0 0 0 2.06E+07 1.10E+07 - - - 3.0553 0.9138 221125_WJC_METTL3_EV_vs_WT_F09.09249.09249.4 0.981 Aug-96 K.SQQPLKPQVHTPVATVK.Q "sp|Q6P3W7|SCYL2_HUMAN,tr|A0A0U1RQQ9|A0A0U1RQQ9_HUMAN" 2 1857.0472 1.88 129407 9249 4 1857.052109 465.2691 SCY1-like protein 2 OS=Homo sapiens OX=9606 GN=SCYL2 PE=1 SV=1 10 2020.8 - 313427 - - - 2.6262 - 1.53 0.154 - 32.2 1 2 0 0.0049 17 0 0 0 9.58E+07 5.09E+07 - - - 0.7127 0.9999 221125_WJC_METTL3_EV_vs_WT_F09.09253.09253.3 0.00239 Sep-64 R.LEHAFC[160.03]TETRPYNQGAR.L sp|Q9BV20|MTNA_HUMAN 1 2048.9487 3.16 129411 9253 3 2048.949342 683.9902 Methylthioribose-1-phosphate isomerase OS=Homo sapiens OX=9606 GN=MRI1 PE=1 SV=1 6.75 2021.3 - 90795.5 - - - 0.3343 - 1.625 0.466 - 97.4 1 2 0 0.0007 17 0 0 0 1.28E+06 4.03E+05 - - - 4.9618 0.9998 221125_WJC_METTL3_EV_vs_WT_F09.09260.09260.2 4.37E-07 30-Sep R.STDSSSVSGSLQQETK[136.11].Y "sp|Q9H8G2|CAAP1_HUMAN,tr|A0A3B3ISJ3|A0A3B3ISJ3_HUMAN" 2 1647.7679 1.08 129416 9260 2 1647.770639 824.8912 Caspase activity and apoptosis inhibitor 1 OS=Homo sapiens OX=9606 GN=CAAP1 PE=1 SV=2 4.37 2022.1 - 81781.6 - - - 1.6695 - 2.258 0.632 - 174.3 1 2 0 0.0027 16 0 0 0 7.15E+06 6.63E+06 - - - 5.7105 1 221125_WJC_METTL3_EV_vs_WT_F09.09264.09264.3 4.22E-08 15/64 R.LEKPETQSSPITVQSSK.D "sp|Q96CB8|INT12_HUMAN,tr|A0A087WXN4|A0A087WXN4_HUMAN,tr|E9PGI3|E9PGI3_HUMAN" 3 1857.9684 1.25 129417 9264 3 1857.971807 620.3301 Integrator complex subunit 12 OS=Homo sapiens OX=9606 GN=INTS12 PE=1 SV=1 6.14 2022.7 - 2.41E+06 - - - 1.8483 - 2.912 0.548 - 282.2 1 2 0 0.0034 17 0 0 0 1.38E+08 1.10E+08 - - - 7.3489 0.9989 221125_WJC_METTL3_EV_vs_WT_F09.09267.09267.4 0.0143 Oct-96 K.SQQPLK[136.11]PQVHTPVATVK[136.11].Q "sp|Q6P3W7|SCYL2_HUMAN,tr|A0A0U1RQQ9|A0A0U1RQQ9_HUMAN" 2 1873.0756 1.88 129420 9267 4 1873.078612 469.2762 SCY1-like protein 2 OS=Homo sapiens OX=9606 GN=SCYL2 PE=1 SV=1 10 2023.1 - 417754 - - - 1.591 - 1.85 0.305 - 45.8 1 2 0 0.003 17 0 0 0 9.58E+07 5.09E+07 - - - 2.0935 0.9999 221125_WJC_METTL3_EV_vs_WT_F09.09269.09269.2 3.03E-07 30-Oct R.STDSSSVSGSLQQETK.Y "sp|Q9H8G2|CAAP1_HUMAN,tr|A0A3B3ISJ3|A0A3B3ISJ3_HUMAN" 2 1639.7537 1.08 129422 9269 2 1639.754757 820.8841 Caspase activity and apoptosis inhibitor 1 OS=Homo sapiens OX=9606 GN=CAAP1 PE=1 SV=2 4.37 2023.3 - 138978 - - - 0.6519 - 2.415 0.574 - 213.1 1 2 0 0.0011 16 0 0 0 7.15E+06 6.63E+06 - - - 5.4479 0.9999 221125_WJC_METTL3_EV_vs_WT_F09.09275.09275.3 0.000528 13/64 K.SAVSTSVPTK[136.11]PTENISK[136.11].A sp|Q5VT52|RPRD2_HUMAN 1 1760.9491 2.33 129426 9275 3 1760.95088 587.9903 Regulation of nuclear pre-mRNA domain-containing protein 2 OS=Homo sapiens OX=9606 GN=RPRD2 PE=1 SV=1 8.31 2024.1 - 473710 - - - 1.0142 - 2.159 0.417 - 194.1 1 2 0 0.0018 17 0 0 0 2.61E+07 1.12E+07 - - - 5.133 0.9991 221125_WJC_METTL3_EV_vs_WT_F09.09276.09276.3 0.00243 Oct-56 K.AENKGNDPNVNIVPK.D "sp|Q9Y520|PRC2C_HUMAN,tr|E7EPN9|E7EPN9_HUMAN" 2 1607.8267 1.29 129427 9276 3 1607.826316 536.9495 Protein PRRC2C OS=Homo sapiens OX=9606 GN=PRRC2C PE=1 SV=4 6.11 2024.2 - 437891 - - - -0.26 - 1.828 0.402 - 85.4 1 2 1 -0.0004 15 0 0 0 5.21E+07 4.06E+07 - - - 4.5958 0.9943 221125_WJC_METTL3_EV_vs_WT_F09.09278.09278.3 0.0283 Jun-40 K.EAIEGTYIDKK.C "sp|P62280|RS11_HUMAN,tr|M0QZC5|M0QZC5_HUMAN" 2 1265.6503 0.93 129429 9278 3 1265.650206 422.8907 40S ribosomal protein S11 OS=Homo sapiens OX=9606 GN=RPS11 PE=1 SV=3 4.68 2024.5 - 170745 - - - -0.1003 - 1.232 0.283 - 61.3 2 2 0 -0.0001 11 0 0 0 2.90E+06 3.11E+06 - - - 2.1485 0.9973 221125_WJC_METTL3_EV_vs_WT_F09.09281.09281.4 5.13E-07 Oct-78 K.KNDLVDADNKNLVR.L sp|P41214|EIF2D_HUMAN 1 1612.8533 1.48 129430 9281 4 1612.851965 404.2206 Eukaryotic translation initiation factor 2D OS=Homo sapiens OX=9606 GN=EIF2D PE=1 SV=3 6.04 2024.9 - 99408.6 - - - -0.8172 - 1.933 0.316 - 76 1 2 1 -0.0013 14 0 0 0 1.86E+06 1.25E+06 - - - 2.216 0.9054 221125_WJC_METTL3_EV_vs_WT_F09.09283.09283.3 0.117 Jul-48 K.IQDKEGIPPDQQR.L "sp|P62979|RS27A_HUMAN,sp|P0CG48|UBC_HUMAN,sp|P0CG48|UBC_HUMAN,sp|P0CG48|UBC_HUMAN,sp|P0CG48|UBC_HUMAN,sp|P0CG48|UBC_HUMAN,sp|P0CG48|UBC_HUMAN,sp|P0CG48|UBC_HUMAN,sp|P0CG48|UBC_HUMAN,sp|P0CG48|UBC_HUMAN,sp|P0CG47|UBB_HUMAN,sp|P0CG47|UBB_HUMAN,sp|P0CG47|UBB_HUMAN,sp|P62987|RL40_HUMAN,tr|F5H388|F5H388_HUMAN,tr|F5H388|F5H388_HUMAN,tr|F5GYU3|F5GYU3_HUMAN,tr|F5GYU3|F5GYU3_HUMAN,tr|B4DV12|B4DV12_HUMAN,tr|B4DV12|B4DV12_HUMAN,tr|J3QSA3|J3QSA3_HUMAN,tr|Q5PY61|Q5PY61_HUMAN,tr|Q5PY61|Q5PY61_HUMAN,tr|Q5PY61|Q5PY61_HUMAN,tr|F5H2Z3|F5H2Z3_HUMAN,tr|F5H2Z3|F5H2Z3_HUMAN,tr|M0R2S1|M0R2S1_HUMAN,tr|J3QS39|J3QS39_HUMAN,tr|J3QTR3|J3QTR3_HUMAN,tr|Q96C32|Q96C32_HUMAN,tr|Q96C32|Q96C32_HUMAN,tr|Q96C32|Q96C32_HUMAN,tr|Q96C32|Q96C32_HUMAN,tr|M0R1V7|M0R1V7_HUMAN,tr|F5H747|F5H747_HUMAN,tr|F5H747|F5H747_HUMAN,tr|F5GXK7|F5GXK7_HUMAN,tr|F5GXK7|F5GXK7_HUMAN,tr|M0R1M6|M0R1M6_HUMAN,tr|F5H6Q2|F5H6Q2_HUMAN,tr|F5H6Q2|F5H6Q2_HUMAN,tr|F5GZ39|F5GZ39_HUMAN,tr|J3QKN0|J3QKN0_HUMAN,tr|J3QKN0|J3QKN0_HUMAN,tr|F5H265|F5H265_HUMAN,tr|F5H265|F5H265_HUMAN,tr|A0A2R8Y422|A0A2R8Y422_HUMAN" 47 1522.774 0.72 129431 9283 3 1522.770881 508.5986 Ubiquitin-40S ribosomal protein S27a OS=Homo sapiens OX=9606 GN=RPS27A PE=1 SV=2 4.56 2025.1 - 188160 - - - -2.0285 - 1.555 0.175 - 71.2 1 2 1 -0.0031 13 0 0 0 4.17E+06 5.79E+06 - - - 1.6872 0.9932 221125_WJC_METTL3_EV_vs_WT_F09.09285.09285.2 0.0437 Apr-32 R.LEK[136.11]PETQSSPITVQSSK[136.11].D "sp|Q96CB8|INT12_HUMAN,tr|A0A087WXN4|A0A087WXN4_HUMAN,tr|E9PGI3|E9PGI3_HUMAN" 3 1873.9968 1.22 129432 9285 2 1873.992434 938.0057 Integrator complex subunit 12 OS=Homo sapiens OX=9606 GN=INTS12 PE=1 SV=1 6.14 2025.5 - 48564.8 - - - -2.3154 - 1.108 0.314 - 22.7 1 2 0 -0.0043 17 0 0 0 1.69E+06 1.39E+06 - - - 1.611 1 221125_WJC_METTL3_EV_vs_WT_F09.09292.09292.3 2.73E-08 13/52 K.K[136.11]GPGEVAGTVTGQK[136.11].R "sp|Q86U44|MTA70_HUMAN,tr|F5H6D8|F5H6D8_HUMAN,tr|H0YFV6|H0YFV6_HUMAN,tr|B4DTN4|B4DTN4_HUMAN" 4 1343.738 0.01 129436 9292 3 1343.736469 448.9199 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 8.59 2026.4 - 467301 - - - -1.1237 - 2.574 0.602 - 296.9 1 2 0 -0.0015 14 0 0 0 2.16E+05 1.53E+07 - - - 7.7639 0.8266 221125_WJC_METTL3_EV_vs_WT_F09.09295.09295.3 0.00408 Sep-52 L.KVVDRDSEEAEIIR.K "sp|P09874|PARP1_HUMAN,tr|A0A7I2V3E1|A0A7I2V3E1_HUMAN" 2 1657.8635 2.4 129437 9295 3 1657.865612 553.6284 Poly [ADP-ribose] polymerase 1 OS=Homo sapiens OX=9606 GN=PARP1 PE=1 SV=4 4.51 2026.8 - 276027 - - - 1.2655 - 1.985 0.337 - 121.3 1 1 1 0.0021 14 0 0 0 8.96E+06 3.73E+06 - - - 4.1187 0.9999 221125_WJC_METTL3_EV_vs_WT_F09.09302.09302.3 3.14E-06 17/64 K.VEEKPPPAPSIATKPVR.T "sp|Q9Y520|PRC2C_HUMAN,tr|E7EPN9|E7EPN9_HUMAN,tr|H7C5N8|H7C5N8_HUMAN,tr|A0A2R8YET2|A0A2R8YET2_HUMAN" 4 1815.0254 2.89 129442 9302 3 1815.024844 606.0158 Protein PRRC2C OS=Homo sapiens OX=9606 GN=PRRC2C PE=1 SV=4 8.56 2027.7 - 642250 - - - -0.3251 - 3.02 0.407 - 335.4 1 2 0 -0.0006 17 0 0 0 2.29E+07 7.94E+06 - - - 5.8697 1 221125_WJC_METTL3_EV_vs_WT_F09.09304.09304.3 9.94E-07 14/64 K.VEEK[136.11]PPPAPSIATK[136.11]PVR[166.11].T "sp|Q9Y520|PRC2C_HUMAN,tr|E7EPN9|E7EPN9_HUMAN,tr|H7C5N8|H7C5N8_HUMAN,tr|A0A2R8YET2|A0A2R8YET2_HUMAN" 4 1841.0621 3.01 129444 9304 3 1841.06452 614.6946 Protein PRRC2C OS=Homo sapiens OX=9606 GN=PRRC2C PE=1 SV=4 8.56 2028 - 189869 - - - 1.3123 - 2.81 0.49 - 158.1 1 2 0 0.0024 17 0 0 0 2.43E+07 8.06E+06 - - - 6.6125 1 221125_WJC_METTL3_EV_vs_WT_F09.09311.09311.3 4.62E-10 24/68 N.VSVSVSTSHTTISGGGSR.G sp|P04264|K2C1_HUMAN 1 1717.8595 111.53 129449 9311 3 1717.859979 573.6271 "Keratin, type II cytoskeletal 1 OS=Homo sapiens OX=9606 GN=KRT1 PE=1 SV=6" 9.73 2028.9 - 1.46E+06 - - - 0.2841 - 4.299 0.645 - 913.3 1 1 0 0.0005 18 0 0 0 2.54E+07 2.28E+05 - - - 9.3625 0.9571 221125_WJC_METTL3_EV_vs_WT_F09.09317.09317.3 0.0291 Apr-64 R.GGPNQPGQGFKEDTPVR.H sp|Q8IYN2|TCAL8_HUMAN 1 1782.8649 1.35 129453 9317 3 1782.865701 595.2956 Transcription elongation factor A protein-like 8 OS=Homo sapiens OX=9606 GN=TCEAL8 PE=1 SV=1 6.07 2029.7 - 163574 - - - 0.4431 - 1.273 0.299 - 15.6 26 2 1 0.0008 17 0 0 0 3.88E+06 2.87E+06 - - - 1.8282 0.9998 221125_WJC_METTL3_EV_vs_WT_F09.09318.09318.4 0.00257 Aug-72 K.TVFAEHISDEC[160.03]K[136.11]R[166.11].R "sp|P39023|RL3_HUMAN,tr|G5E9G0|G5E9G0_HUMAN,tr|H7C3M2|H7C3M2_HUMAN,tr|F8WCR1|F8WCR1_HUMAN,tr|B5MCW2|B5MCW2_HUMAN,tr|H7C422|H7C422_HUMAN" 6 1608.7685 0.92 129454 9318 4 1608.770004 403.1994 60S ribosomal protein L3 OS=Homo sapiens OX=9606 GN=RPL3 PE=1 SV=2 5.41 2029.8 - 144884 - - - 0.928 - 1.448 0.39 - 32.5 1 2 0 0.0015 13 0 0 0 2.40E+06 2.61E+06 - - - 2.7574 0.9989 221125_WJC_METTL3_EV_vs_WT_F09.09320.09320.2 0.000981 Jul-32 R.LEKPETQSSPITVQSSK.D "sp|Q96CB8|INT12_HUMAN,tr|A0A087WXN4|A0A087WXN4_HUMAN,tr|E9PGI3|E9PGI3_HUMAN" 3 1857.9684 1.22 129456 9320 2 1857.972981 929.9915 Integrator complex subunit 12 OS=Homo sapiens OX=9606 GN=INTS12 PE=1 SV=1 6.14 2030.1 - 76970.5 - - - 2.4801 - 1.464 0.463 - 62.1 1 2 0 0.0046 17 0 0 0 1.69E+06 1.39E+06 - - - 3.3964 0.9998 221125_WJC_METTL3_EV_vs_WT_F09.09326.09326.4 0.000137 Dec-72 K.TVFAEHISDEC[160.03]KR.R "sp|P39023|RL3_HUMAN,tr|G5E9G0|G5E9G0_HUMAN,tr|H7C3M2|H7C3M2_HUMAN,tr|F8WCR1|F8WCR1_HUMAN,tr|B5MCW2|B5MCW2_HUMAN,tr|H7C422|H7C422_HUMAN" 6 1590.746 0.92 129460 9326 4 1590.743671 398.6938 60S ribosomal protein L3 OS=Homo sapiens OX=9606 GN=RPL3 PE=1 SV=2 5.41 2030.9 - 221466 - - - -1.4899 - 2.139 0.39 - 55.9 1 2 0 -0.0024 13 0 0 0 2.40E+06 2.61E+06 - - - 2.9018 0.9997 221125_WJC_METTL3_EV_vs_WT_F09.09335.09335.3 0.00031 Nov-64 R.QDPPSVVVTSHQAPGEK.K sp|P25311|ZA2G_HUMAN 1 1774.885 999 129467 9335 3 1774.888825 592.6356 Zinc-alpha-2-glycoprotein OS=Homo sapiens OX=9606 GN=AZGP1 PE=1 SV=2 5.32 2032.1 - 150308 - - - 2.168 - 2.012 0.416 - 106.3 1 2 0 0.0038 17 0 0 0 2.96E+07 0.00E+00 - - - 4.9431 1 221125_WJC_METTL3_EV_vs_WT_F09.09339.09339.3 2.36E-10 14/48 K.VDNDENEHQLSLR.T "sp|P06748|NPM_HUMAN,tr|A0A7I2V4G8|A0A7I2V4G8_HUMAN,tr|A0A7I2YQC0|A0A7I2YQC0_HUMAN,tr|A0A7I2V433|A0A7I2V433_HUMAN,tr|A0A7I2V579|A0A7I2V579_HUMAN,tr|A0A7I2V2X9|A0A7I2V2X9_HUMAN,tr|A0A7I2V3G5|A0A7I2V3G5_HUMAN,tr|A0A7I2V5S2|A0A7I2V5S2_HUMAN,tr|A0A7I2V3U2|A0A7I2V3U2_HUMAN,tr|E5RGW4|E5RGW4_HUMAN" 10 1567.7227 0.85 129469 9339 3 1567.725525 523.5815 Nucleophosmin OS=Homo sapiens OX=9606 GN=NPM1 PE=1 SV=2 4.31 2032.6 - 843284 - - - 1.8256 - 2.904 0.614 - 484.5 1 2 0 0.0029 13 0 0 0 1.84E+07 2.17E+07 - - - 8.2752 1 221125_WJC_METTL3_EV_vs_WT_F09.09341.09341.3 3.29E-08 Dec-68 K.QR[166.11]PLTASLQC[160.03]NSTAQTEK[136.11].V "sp|Q9UFW8|CGBP1_HUMAN,tr|C9JUJ0|C9JUJ0_HUMAN" 2 2050.0232 3.88 129471 9341 3 2050.021926 684.3484 CGG triplet repeat-binding protein 1 OS=Homo sapiens OX=9606 GN=CGGBP1 PE=1 SV=2 8.22 2032.9 - 165353 - - - -0.6322 - 2.111 0.585 - 162.6 1 2 0 -0.0013 18 0 0 0 4.41E+07 1.13E+07 - - - 6.9223 0.9996 221125_WJC_METTL3_EV_vs_WT_F09.09343.09343.3 0.00129 Nov-76 R.GDNQAGGAAAAAAAPEPPPR.S "sp|O14654|IRS4_HUMAN,tr|A0A804CF45|A0A804CF45_HUMAN" 2 1787.8551 0.68 129473 9343 3 1787.851153 596.959 Insulin receptor substrate 4 OS=Homo sapiens OX=9606 GN=IRS4 PE=1 SV=1 4.37 2033.2 - 125882 - - - -2.1931 - 1.691 0.421 - 88.8 1 2 0 -0.0039 20 0 0 0 3.17E+06 4.68E+06 - - - 4.5071 0.9984 221125_WJC_METTL3_EV_vs_WT_F09.09346.09346.4 0.000922 12/102 R.VILDEGHAIR[166.11]NPNAQQTK[136.11].A "sp|Q14527|HLTF_HUMAN,tr|H7C5K0|H7C5K0_HUMAN,tr|A0A0C4DGA6|A0A0C4DGA6_HUMAN" 3 2021.0773 1.27 129474 9346 4 2021.08137 506.2766 Helicase-like transcription factor OS=Homo sapiens OX=9606 GN=HLTF PE=1 SV=2 6.72 2033.6 - 302358 - - - 2.0103 - 2.266 0.366 - 85.1 1 2 1 0.0041 18 0 0 0 1.81E+07 1.43E+07 - - - 2.6908 0.9987 221125_WJC_METTL3_EV_vs_WT_F09.09347.09347.3 0.002 Oct-64 R.GGPNQPGQGFK[136.11]EDTPVR[166.11].H sp|Q8IYN2|TCAL8_HUMAN 1 1800.8874 2.25 129475 9347 3 1800.888092 601.3031 Transcription elongation factor A protein-like 8 OS=Homo sapiens OX=9606 GN=TCEAL8 PE=1 SV=1 6.07 2033.7 - 138795 - - - 0.3948 - 1.913 0.369 - 86.2 1 2 1 0.0007 17 0 0 0 6.84E+06 3.05E+06 - - - 4.2925 1 221125_WJC_METTL3_EV_vs_WT_F09.09348.09348.2 3.99E-09 28-Nov R.SDSPVPTAPTSGGPK[136.11].P "sp|Q86U44|MTA70_HUMAN,tr|B4E349|B4E349_HUMAN,tr|F5H6D8|F5H6D8_HUMAN,tr|B4DTN4|B4DTN4_HUMAN" 4 1404.6976 0.02 129476 9348 2 1404.696902 703.3561 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 5.55 2033.9 - 229376 - - - -0.514 - 2.306 0.633 - 247.9 1 1 0 -0.0007 15 0 0 0 1.44E+06 7.58E+07 - - - 5.7703 0.9975 221125_WJC_METTL3_EV_vs_WT_F09.09350.09350.3 0.0246 Jul-68 K.QNMGPSGQTHPPPQTLPR[166.11].S sp|Q9NTZ6|RBM12_HUMAN 1 1951.9562 1.55 129478 9350 3 1951.958691 651.6593 RNA-binding protein 12 OS=Homo sapiens OX=9606 GN=RBM12 PE=1 SV=1 9.76 2034.1 - 102924 - - - 1.2767 - 1.739 0.263 - 46.5 1 2 0 0.0025 18 0 0 0 3.03E+06 1.95E+06 - - - 2.8493 0.984 221125_WJC_METTL3_EV_vs_WT_F09.09354.09354.3 0.00413 Nov-48 R.QTAQQIVSHVQNK[136.11].G sp|Q9NZB2|F120A_HUMAN 1 1487.7936 0.88 129480 9354 3 1487.798081 496.9385 Constitutive coactivator of PPAR-gamma-like protein 1 OS=Homo sapiens OX=9606 GN=FAM120A PE=1 SV=2 8.76 2034.7 - 214253 - - - 3.0186 - 2.096 0.162 - 208.5 1 2 0 0.0045 13 0 0 0 3.00E+07 3.41E+07 - - - 2.3513 0.998 221125_WJC_METTL3_EV_vs_WT_F09.09355.09355.4 0.000638 Nov-72 R.TDFK[136.11]EEPEPGFK[136.11]R[166.11].L "sp|P47897|SYQ_HUMAN,tr|B4DDN1|B4DDN1_HUMAN,tr|H7C0R3|H7C0R3_HUMAN,tr|A0A0U1RQX5|A0A0U1RQX5_HUMAN,tr|A0A1B0GVU9|A0A1B0GVU9_HUMAN,tr|A0A0U1RRC8|A0A0U1RRC8_HUMAN" 6 1604.8045 1.16 129481 9355 4 1604.809117 402.2084 Glutamine--tRNA ligase OS=Homo sapiens OX=9606 GN=QARS1 PE=1 SV=1 4.87 2034.8 - 335429 - - - 2.882 - 1.955 0.392 - 103.6 1 2 1 0.0046 13 0 0 0 2.11E+07 1.82E+07 - - - 2.8852 0.9999 221125_WJC_METTL3_EV_vs_WT_F09.09356.09356.3 0.000319 14/64 K.SQQPLKPQVHTPVATVK.Q "sp|Q6P3W7|SCYL2_HUMAN,tr|A0A0U1RQQ9|A0A0U1RQQ9_HUMAN" 2 1857.0472 1.99 129482 9356 3 1857.051928 620.023 SCY1-like protein 2 OS=Homo sapiens OX=9606 GN=SCYL2 PE=1 SV=1 10 2034.9 - 979100 - - - 2.5287 - 2.39 0.5 - 206.2 1 2 0 0.0047 17 0 0 0 5.23E+07 2.63E+07 - - - 6.3144 0.8796 221125_WJC_METTL3_EV_vs_WT_F09.09361.09361.2 5.29 24-Mar K.VDNDENEHQLSLR[166.11].T "sp|P06748|NPM_HUMAN,tr|A0A7I2V4G8|A0A7I2V4G8_HUMAN,tr|A0A7I2YQC0|A0A7I2YQC0_HUMAN,tr|A0A7I2V433|A0A7I2V433_HUMAN,tr|A0A7I2V579|A0A7I2V579_HUMAN,tr|A0A7I2V2X9|A0A7I2V2X9_HUMAN,tr|A0A7I2V3G5|A0A7I2V3G5_HUMAN,tr|A0A7I2V5S2|A0A7I2V5S2_HUMAN,tr|A0A7I2V3U2|A0A7I2V3U2_HUMAN,tr|E5RGW4|E5RGW4_HUMAN" 10 1577.7309 0.48 129487 9361 2 1577.732962 789.8727 Nucleophosmin OS=Homo sapiens OX=9606 GN=NPM1 PE=1 SV=2 4.31 2035.5 - 44532.4 - - - 1.286 - 0.715 0.143 - 22.4 1 2 0 0.002 13 0 0 0 1.82E+05 3.76E+05 - - - -0.7644 0.9969 221125_WJC_METTL3_EV_vs_WT_F09.09364.09364.4 4.47E-05 17/102 R.VILDEGHAIRNPNAQQTK.A "sp|Q14527|HLTF_HUMAN,tr|H7C5K0|H7C5K0_HUMAN,tr|A0A0C4DGA6|A0A0C4DGA6_HUMAN" 3 2003.0548 1.16 129488 9364 4 2003.06193 501.771 Helicase-like transcription factor OS=Homo sapiens OX=9606 GN=HLTF PE=1 SV=2 6.72 2036 - 827101 - - - 3.5411 - 2.943 0.38 - 158.1 1 2 1 0.0071 18 0 0 0 1.82E+07 1.57E+07 - - - 2.9013 0.996 221125_WJC_METTL3_EV_vs_WT_F09.09365.09365.4 0.000179 Dec-72 R.TDFKEEPEPGFKR.L "sp|P47897|SYQ_HUMAN,tr|B4DDN1|B4DDN1_HUMAN,tr|H7C0R3|H7C0R3_HUMAN,tr|A0A0U1RQX5|A0A0U1RQX5_HUMAN,tr|A0A1B0GVU9|A0A1B0GVU9_HUMAN,tr|A0A0U1RRC8|A0A0U1RRC8_HUMAN" 6 1578.7678 1 129489 9365 4 1578.772646 395.6992 Glutamine--tRNA ligase OS=Homo sapiens OX=9606 GN=QARS1 PE=1 SV=1 4.87 2036.2 - 599078 - - - 3.0555 - 2.225 0.352 - 104 1 2 1 0.0048 13 0 0 0 2.19E+07 2.19E+07 - - - 2.585 0.9965 221125_WJC_METTL3_EV_vs_WT_F09.09366.09366.3 0.212 Sep-68 K.NKPGPYSSVPPPSAPPPK.K "sp|Q14978|NOLC1_HUMAN,tr|A0A0A0MRM9|A0A0A0MRM9_HUMAN,tr|S4R349|S4R349_HUMAN" 3 1815.9519 2.56 129490 9366 3 1815.956155 606.3246 Nucleolar and coiled-body phosphoprotein 1 OS=Homo sapiens OX=9606 GN=NOLC1 PE=1 SV=2 9.7 2036.3 - 404170 - - - 2.3239 - 2.001 0.25 - 92.8 1 2 0 0.0042 18 0 0 0 3.06E+07 1.19E+07 - - - 3.0533 0.9983 221125_WJC_METTL3_EV_vs_WT_F09.09367.09367.3 0.00125 Sep-68 R.VILDEGHAIRNPNAQQTK.A "sp|Q14527|HLTF_HUMAN,tr|H7C5K0|H7C5K0_HUMAN,tr|A0A0C4DGA6|A0A0C4DGA6_HUMAN" 3 2003.0548 1.18 129491 9367 3 2003.060373 668.6922 Helicase-like transcription factor OS=Homo sapiens OX=9606 GN=HLTF PE=1 SV=2 6.72 2036.4 - 257647 - - - 2.7638 - 2.127 0.418 - 55.8 1 2 1 0.0055 18 0 0 0 5.96E+06 5.06E+06 - - - 5.0781 0.9978 221125_WJC_METTL3_EV_vs_WT_F09.09368.09368.3 6.13E-07 Dec-64 R.SSEEPTEKEPPGQLQVK.A "sp|Q9ULV3|CIZ1_HUMAN,tr|Q5SYW2|Q5SYW2_HUMAN,tr|F5H2X7|F5H2X7_HUMAN,tr|H0Y5D5|H0Y5D5_HUMAN,tr|A0A494C0L7|A0A494C0L7_HUMAN,tr|Q9BTG3|Q9BTG3_HUMAN" 6 1881.932 4.84 129492 9368 3 1881.936302 628.3179 Cip1-interacting zinc finger protein OS=Homo sapiens OX=9606 GN=CIZ1 PE=1 SV=2 4.49 2036.5 - 250848 - - - 2.2929 - 2.49 0.332 - 159 1 2 1 0.0043 17 0 0 0 1.51E+07 3.12E+06 - - - 4.545 0.9895 221125_WJC_METTL3_EV_vs_WT_F09.09372.09372.3 0.482 15/48 R.QTAQQIVSHVQNK.G sp|Q9NZB2|F120A_HUMAN 1 1479.7794 0.88 129494 9372 3 1479.784402 494.2671 Constitutive coactivator of PPAR-gamma-like protein 1 OS=Homo sapiens OX=9606 GN=FAM120A PE=1 SV=2 8.76 2037.1 - 851763 - - - 3.387 - 1.783 0.242 - 224.9 1 2 0 0.005 13 0 0 0 3.00E+07 3.41E+07 - - - 2.8046 0.9996 221125_WJC_METTL3_EV_vs_WT_F09.09374.09374.4 0.00617 Sep-84 K.DSEADRFSDSHNALR.L sp|Q8TEM1|PO210_HUMAN 1 1718.7608 1.45 129496 9374 4 1718.763699 430.6975 Nuclear pore membrane glycoprotein 210 OS=Homo sapiens OX=9606 GN=NUP210 PE=1 SV=3 4.66 2037.4 - 186109 - - - 1.664 - 1.698 0.443 - 59.1 1 2 1 0.0029 15 0 0 0 3.22E+06 2.22E+06 - - - 3.2705 0.9999 221125_WJC_METTL3_EV_vs_WT_F09.09375.09375.3 8.08E-06 Sep-48 K.DSSDPNELYVNHK[136.11].V "sp|O15160|RPAC1_HUMAN,tr|D6RDJ3|D6RDJ3_HUMAN,tr|A0A2R8YEZ4|A0A2R8YEZ4_HUMAN,tr|E7EQB9|E7EQB9_HUMAN,tr|A0A2R8Y5D3|A0A2R8Y5D3_HUMAN,tr|A0A2R8YEY5|A0A2R8YEY5_HUMAN" 6 1524.6936 0.27 129497 9375 3 1524.695968 509.2385 DNA-directed RNA polymerases I and III subunit RPAC1 OS=Homo sapiens OX=9606 GN=POLR1C PE=1 SV=1 4.54 2037.5 - 128325 - - - 1.5524 - 1.672 0.529 - 90.7 1 2 0 0.0024 13 0 0 0 2.06E+06 7.70E+06 - - - 5.8308 0.976 221125_WJC_METTL3_EV_vs_WT_F09.09378.09378.3 0.024 Aug-68 K.NK[136.11]PGPYSSVPPPSAPPPK[136.11].K "sp|Q14978|NOLC1_HUMAN,tr|A0A0A0MRM9|A0A0A0MRM9_HUMAN,tr|S4R349|S4R349_HUMAN" 3 1831.9803 2.56 129499 9378 3 1831.989506 611.6674 Nucleolar and coiled-body phosphoprotein 1 OS=Homo sapiens OX=9606 GN=NOLC1 PE=1 SV=2 9.7 2037.9 - 131032 - - - 5.0061 - 1.641 0.293 - 59.9 1 2 0 0.0092 18 0 0 0 3.00E+07 1.17E+07 - - - 3.0375 0.9998 221125_WJC_METTL3_EV_vs_WT_F09.09381.09381.3 8.66E-05 13/68 R.VILDEGHAIR[166.11]NPNAQQTK[136.11].A "sp|Q14527|HLTF_HUMAN,tr|H7C5K0|H7C5K0_HUMAN,tr|A0A0C4DGA6|A0A0C4DGA6_HUMAN" 3 2021.0773 1.24 129501 9381 3 2021.079609 674.6997 Helicase-like transcription factor OS=Homo sapiens OX=9606 GN=HLTF PE=1 SV=2 6.72 2038.2 - 284400 - - - 1.139 - 2.351 0.514 - 143.9 1 2 1 0.0023 18 0 0 0 5.94E+06 4.78E+06 - - - 6.3986 0.9965 221125_WJC_METTL3_EV_vs_WT_F09.09388.09388.3 3.14E-07 16/48 R.TDFKEEPEPGFKR.L "sp|P47897|SYQ_HUMAN,tr|B4DDN1|B4DDN1_HUMAN,tr|H7C0R3|H7C0R3_HUMAN,tr|A0A0U1RQX5|A0A0U1RQX5_HUMAN,tr|A0A1B0GVU9|A0A1B0GVU9_HUMAN,tr|A0A0U1RRC8|A0A0U1RRC8_HUMAN" 6 1578.7678 0.86 129506 9388 3 1578.779079 527.2632 Glutamine--tRNA ligase OS=Homo sapiens OX=9606 GN=QARS1 PE=1 SV=1 4.87 2039.2 - 769757 - - - 7.1302 - 2.897 0.577 - 326.7 1 2 1 0.0113 13 0 0 0 1.21E+07 1.40E+07 - - - 7.8538 0.9985 221125_WJC_METTL3_EV_vs_WT_F09.09390.09390.2 0.0234 24-Jun R.QTAQQIVSHVQNK.G sp|Q9NZB2|F120A_HUMAN 1 1479.7794 0.83 129508 9390 2 1479.783139 740.897 Constitutive coactivator of PPAR-gamma-like protein 1 OS=Homo sapiens OX=9606 GN=FAM120A PE=1 SV=2 8.76 2039.5 - 86400.4 - - - 2.5335 - 1.55 0.4 - 132.2 1 2 0 0.0037 13 0 0 0 1.64E+06 1.97E+06 - - - 3.119 1 221125_WJC_METTL3_EV_vs_WT_F09.09397.09397.2 1.87E-09 Sep-40 R.GGSGGSHGGGSGFGGESGGSY.G "sp|P35527|K1C9_HUMAN,tr|K7EQQ3|K7EQQ3_HUMAN" 2 1713.6615 - 129513 9397 2 1713.666426 857.838 "Keratin, type I cytoskeletal 9 OS=Homo sapiens OX=9606 GN=KRT9 PE=1 SV=3" 5.24 2040.6 - 101869 - - - 2.8635 - 2.504 0.81 - 103.7 1 1 0 0.0049 21 0 0 0 - - - - - 7.2788 0.9998 221125_WJC_METTL3_EV_vs_WT_F09.09400.09400.4 0.00014 Dec-90 R.SFGTEDR[166.11]PTDR[166.11]PIPPR[166.11].D "sp|Q8ND56|LS14A_HUMAN,tr|I3L4Q1|I3L4Q1_HUMAN,tr|A0A140TA76|A0A140TA76_HUMAN,tr|K7EMZ9|K7EMZ9_HUMAN" 4 1869.9476 0.99 129516 9400 4 1869.953119 468.4942 Protein LSM14 homolog A OS=Homo sapiens OX=9606 GN=LSM14A PE=1 SV=3 5.84 2041 - 189034 - - - 2.9675 - 2.181 0.447 - 88.1 1 2 0 0.0056 16 0 0 0 1.47E+07 1.49E+07 - - - 3.3898 1 221125_WJC_METTL3_EV_vs_WT_F09.09405.09405.3 0.000103 Oct-76 K.SFAANGIQAHPESSTGSDAR[166.11].T "sp|Q5QJE6|TDIF2_HUMAN,tr|E9PRB3|E9PRB3_HUMAN,tr|J3KP30|J3KP30_HUMAN" 3 2011.9223 1.93 129519 9405 3 2011.92389 671.648 Deoxynucleotidyltransferase terminal-interacting protein 2 OS=Homo sapiens OX=9606 GN=DNTTIP2 PE=1 SV=2 5.3 2041.7 - 158069 - - - 0.7823 - 1.963 0.518 - 63.2 1 2 0 0.0016 20 0 0 0 9.38E+06 4.86E+06 - - - 5.951 0.7775 221125_WJC_METTL3_EV_vs_WT_F09.09412.09412.2 3.8 24-Feb K.DSSDPNELYVNHK[136.11].V "sp|O15160|RPAC1_HUMAN,tr|D6RDJ3|D6RDJ3_HUMAN,tr|A0A2R8YEZ4|A0A2R8YEZ4_HUMAN,tr|E7EQB9|E7EQB9_HUMAN,tr|A0A2R8Y5D3|A0A2R8Y5D3_HUMAN,tr|A0A2R8YEY5|A0A2R8YEY5_HUMAN" 6 1524.6936 0.001 129526 9412 2 1524.695354 763.3541 DNA-directed RNA polymerases I and III subunit RPAC1 OS=Homo sapiens OX=9606 GN=POLR1C PE=1 SV=1 4.54 2042.6 - 55484.4 - - - 1.1497 - 0.607 0.187 - 7.6 8 2 0 0.0018 13 0 0 0 0.00E+00 9.32E+05 - - - -1.2631 0.9998 221125_WJC_METTL3_EV_vs_WT_F09.09415.09415.3 1.86E-07 17/56 R.DTNAPESFK[136.11]DTAESR[166.11].S "sp|Q15643|TRIPB_HUMAN,tr|H0YJ97|H0YJ97_HUMAN" 2 1684.7659 1.31 129527 9415 3 1684.771009 562.5959 Thyroid receptor-interacting protein 11 OS=Homo sapiens OX=9606 GN=TRIP11 PE=1 SV=3 4.32 2043 - 316354 - - - 3.0158 - 2.976 0.592 - 430.1 1 2 1 0.0051 15 0 0 0 9.35E+07 7.14E+07 - - - 7.9845 1 221125_WJC_METTL3_EV_vs_WT_F09.09416.09416.3 5.34E-08 15/76 K.SFAANGIQAHPESSTGSDAR.T "sp|Q5QJE6|TDIF2_HUMAN,tr|E9PRB3|E9PRB3_HUMAN,tr|J3KP30|J3KP30_HUMAN" 3 2001.914 2.12 129528 9416 3 2001.918141 668.312 Deoxynucleotidyltransferase terminal-interacting protein 2 OS=Homo sapiens OX=9606 GN=DNTTIP2 PE=1 SV=2 5.3 2043.2 - 319454 - - - 2.0455 - 3.372 0.639 - 175.6 1 2 0 0.0041 20 0 0 0 1.03E+07 4.86E+06 - - - 8.6119 0.9999 221125_WJC_METTL3_EV_vs_WT_F09.09417.09417.4 0.000253 14/78 R.WPTGDNIHAEHQVR.S "sp|Q14671|PUM1_HUMAN,tr|Q5T1Z8|Q5T1Z8_HUMAN,tr|H0YEH2|H0YEH2_HUMAN,tr|Q5T1Z4|Q5T1Z4_HUMAN,tr|E9PR38|E9PR38_HUMAN" 5 1658.7914 1.46 129529 9417 4 1658.795584 415.7051 Pumilio homolog 1 OS=Homo sapiens OX=9606 GN=PUM1 PE=1 SV=3 5.99 2043.3 - 308003 - - - 2.5513 - 2.377 0.514 - 140.2 1 2 0 0.0042 14 0 0 0 1.13E+07 7.74E+06 - - - 4.0138 1 221125_WJC_METTL3_EV_vs_WT_F09.09418.09418.4 3.53E-07 Dec-78 R.WPTGDNIHAEHQVR[166.11].S "sp|Q14671|PUM1_HUMAN,tr|Q5T1Z8|Q5T1Z8_HUMAN,tr|H0YEH2|H0YEH2_HUMAN,tr|Q5T1Z4|Q5T1Z4_HUMAN,tr|E9PR38|E9PR38_HUMAN" 5 1668.7996 1.45 129530 9418 4 1668.802183 418.2072 Pumilio homolog 1 OS=Homo sapiens OX=9606 GN=PUM1 PE=1 SV=3 5.99 2043.4 - 196249 - - - 1.5346 - 2.497 0.525 - 104.1 1 2 0 0.0026 14 0 0 0 1.14E+07 7.84E+06 - - - 4.1279 0.9999 221125_WJC_METTL3_EV_vs_WT_F09.09420.09420.3 0.000287 13/52 R.WPTGDNIHAEHQVR.S "sp|Q14671|PUM1_HUMAN,tr|Q5T1Z8|Q5T1Z8_HUMAN,tr|H0YEH2|H0YEH2_HUMAN,tr|Q5T1Z4|Q5T1Z4_HUMAN,tr|E9PR38|E9PR38_HUMAN" 5 1658.7914 19.75 129532 9420 3 1658.796804 553.9377 Pumilio homolog 1 OS=Homo sapiens OX=9606 GN=PUM1 PE=1 SV=3 5.99 2043.7 - 141515 - - - 3.2867 - 2.451 0.522 - 213 1 2 0 0.0055 14 0 0 0 6.20E+06 3.14E+05 - - - 6.7407 1 221125_WJC_METTL3_EV_vs_WT_F09.09426.09426.3 1.81E-06 21/52 R.K[136.11]NPLPPSVGVVDK[136.11]K[136.11].E sp|Q8NC51|PAIRB_HUMAN 1 1500.909 0.8 129536 9426 3 1500.913534 501.3103 Plasminogen activator inhibitor 1 RNA-binding protein OS=Homo sapiens OX=9606 GN=SERBP1 PE=1 SV=2 9.7 2044.4 - 638249 - - - 3.0115 - 3.763 0.613 - 759.2 1 2 0 0.0045 14 0 0 0 2.76E+07 3.44E+07 - - - 8.8949 0.9977 221125_WJC_METTL3_EV_vs_WT_F09.09430.09430.2 0.00196 28-Jul R.DTNAPESFKDTAESR.S "sp|Q15643|TRIPB_HUMAN,tr|H0YJ97|H0YJ97_HUMAN" 2 1666.7435 1.68 129540 9430 2 1666.744446 834.379 Thyroid receptor-interacting protein 11 OS=Homo sapiens OX=9606 GN=TRIP11 PE=1 SV=3 4.32 2045 - 42001.6 - - - 0.5928 - 1.62 0.542 - 140.6 1 2 1 0.001 15 0 0 0 6.51E+06 3.87E+06 - - - 4.23 0.9998 221125_WJC_METTL3_EV_vs_WT_F09.09435.09435.4 0.000806 Sep-90 R.SFGTEDRPTDRPIPPR.D "sp|Q8ND56|LS14A_HUMAN,tr|I3L4Q1|I3L4Q1_HUMAN,tr|A0A140TA76|A0A140TA76_HUMAN,tr|K7EMZ9|K7EMZ9_HUMAN" 4 1839.9228 1.03 129542 9435 4 1839.926168 460.988 Protein LSM14 homolog A OS=Homo sapiens OX=9606 GN=LSM14A PE=1 SV=3 5.84 2045.8 - 232776 - - - 1.8523 - 1.499 0.432 - 44.7 1 2 0 0.0034 16 0 0 0 1.20E+07 1.16E+07 - - - 3.1278 1 221125_WJC_METTL3_EV_vs_WT_F09.09443.09443.3 4.41E-07 17/52 R.KNPLPPSVGVVDKK.E sp|Q8NC51|PAIRB_HUMAN 1 1476.8664 0.8 129548 9443 3 1476.870491 493.2961 Plasminogen activator inhibitor 1 RNA-binding protein OS=Homo sapiens OX=9606 GN=SERBP1 PE=1 SV=2 9.7 2046.9 - 495552 - - - 2.7606 - 3.19 0.593 - 405.1 1 2 0 0.0041 14 0 0 0 2.82E+07 3.52E+07 - - - 8.233 0.8088 221125_WJC_METTL3_EV_vs_WT_F09.09450.09450.2 0.0594 14-Jul L.KWLDSDAR.N "sp|P34913|HYES_HUMAN,tr|E5RFU2|E5RFU2_HUMAN,tr|E5RFH6|E5RFH6_HUMAN" 3 989.493 1478.7 129553 9450 2 989.496227 495.7538 Bifunctional epoxide hydrolase 2 OS=Homo sapiens OX=9606 GN=EPHX2 PE=1 SV=2 5.96 2047.8 - 683894 - - - 3.2168 - 1.365 0.362 - 296.6 1 1 0 0.0032 8 0 0 0 5.70E+07 3.85E+04 - - - 2.6522 0.9925 221125_WJC_METTL3_EV_vs_WT_F09.09451.09451.3 0.00774 Aug-44 R.DDDK[136.11]AK[136.11]PGFLPK[136.11].G "sp|Q9Y520|PRC2C_HUMAN,tr|E7EPN9|E7EPN9_HUMAN" 2 1353.7355 1.02 129554 9451 3 1353.738799 452.2524 Protein PRRC2C OS=Homo sapiens OX=9606 GN=PRRC2C PE=1 SV=4 6.04 2048 - 274384 - - - 2.4621 - 1.607 0.341 - 64.3 1 2 1 0.0033 12 0 0 0 1.66E+07 1.63E+07 - - - 3.6558 0.9744 221125_WJC_METTL3_EV_vs_WT_F09.09458.09458.3 0.0286 Nov-68 K.LQTASDESYK[136.11]DPTNIQSK[136.11].H sp|Q13813|SPTN1_HUMAN 1 2039.9982 1.46 129559 9458 3 2040.002505 681.0067 "Spectrin alpha chain, non-erythrocytic 1 OS=Homo sapiens OX=9606 GN=SPTAN1 PE=1 SV=3" 4.56 2048.9 - 157452 - - - 2.0961 - 1.455 0.282 - 79.1 1 2 1 0.0043 18 0 0 0 2.25E+07 1.55E+07 - - - 2.6166 0.9994 221125_WJC_METTL3_EV_vs_WT_F09.09459.09459.3 0.000102 Sep-68 K.LQTASDESYKDPTNIQSK.H sp|Q13813|SPTN1_HUMAN 1 2023.9698 1.46 129560 9459 3 2023.973335 675.6639 "Spectrin alpha chain, non-erythrocytic 1 OS=Homo sapiens OX=9606 GN=SPTAN1 PE=1 SV=3" 4.56 2049 - 170435 - - - 1.7322 - 1.905 0.476 - 65.4 1 2 1 0.0035 18 0 0 0 2.25E+07 1.55E+07 - - - 5.4508 0.9987 221125_WJC_METTL3_EV_vs_WT_F09.09460.09460.2 1.27E-05 28-Oct R.DTNAPESFK[136.11]DTAESR[166.11].S "sp|Q15643|TRIPB_HUMAN,tr|H0YJ97|H0YJ97_HUMAN" 2 1684.7659 1.68 129561 9460 2 1684.766167 843.3902 Thyroid receptor-interacting protein 11 OS=Homo sapiens OX=9606 GN=TRIP11 PE=1 SV=3 4.32 2049.2 - 118977 - - - 0.1419 - 1.912 0.586 - 270.8 1 2 1 0.0002 15 0 0 0 6.51E+06 3.87E+06 - - - 4.9626 1 221125_WJC_METTL3_EV_vs_WT_F09.09468.09468.3 2.30E-05 19/56 R.DTNAPESFKDTAESR.S "sp|Q15643|TRIPB_HUMAN,tr|H0YJ97|H0YJ97_HUMAN" 2 1666.7435 1.31 129566 9468 3 1666.749055 556.5884 Thyroid receptor-interacting protein 11 OS=Homo sapiens OX=9606 GN=TRIP11 PE=1 SV=3 4.32 2050.3 - 3.33E+06 - - - 3.358 - 3.671 0.621 - 582.1 1 2 1 0.0056 15 0 0 0 9.35E+07 7.14E+07 - - - 8.8554 1 221125_WJC_METTL3_EV_vs_WT_F09.09472.09472.3 1.47E-06 16/36 K.EHFAQFGHVR.R "sp|Q9GZT3|SLIRP_HUMAN,tr|H0YJW7|H0YJW7_HUMAN,tr|A0A087WUN7|A0A087WUN7_HUMAN,tr|G3V2S9|G3V2S9_HUMAN,tr|H0YJU7|H0YJU7_HUMAN,tr|H0YJ07|H0YJ07_HUMAN,tr|H0YJ40|H0YJ40_HUMAN,tr|G3V4X6|G3V4X6_HUMAN" 8 1226.5945 1.31 129568 9472 3 1226.596845 409.8721 "SRA stem-loop-interacting RNA-binding protein, mitochondrial OS=Homo sapiens OX=9606 GN=SLIRP PE=1 SV=1" 7.02 2050.9 - 1.18E+06 - - - 1.9199 - 2.624 0.594 - 453 1 2 0 0.0024 10 0 0 0 3.28E+07 2.51E+07 - - - 7.9792 1 221125_WJC_METTL3_EV_vs_WT_F09.09473.09473.3 1.79E-09 16/56 K.QDTSSSTTHLAQQLK[136.11].Q sp|Q9NQW6|ANLN_HUMAN 1 1651.8257 0.91 129569 9473 3 1651.828765 551.6158 Anillin OS=Homo sapiens OX=9606 GN=ANLN PE=1 SV=2 6.74 2051 - 317728 - - - 1.8688 - 2.992 0.684 - 487.2 1 2 0 0.0031 15 0 0 0 1.46E+07 1.60E+07 - - - 9.0248 0.997 221125_WJC_METTL3_EV_vs_WT_F09.09475.09475.3 0.0127 Jun-56 K.VSYGIGDEEHDQEGR[166.11].V "sp|P27695|APEX1_HUMAN,tr|G3V3C7|G3V3C7_HUMAN,tr|G3V5M0|G3V5M0_HUMAN,tr|G3V3M6|G3V3M6_HUMAN,tr|G3V359|G3V359_HUMAN" 5 1699.7313 0.3 129571 9475 3 1699.735971 567.5844 DNA-(apurinic or apyrimidinic site) endonuclease OS=Homo sapiens OX=9606 GN=APEX1 PE=1 SV=2 4.17 2051.2 - 80496.6 - - - 2.7322 - 1.312 0.368 - 32.8 1 2 0 0.0046 15 0 0 0 4.01E+05 1.34E+06 - - - 3.3501 0.993 221125_WJC_METTL3_EV_vs_WT_F09.09490.09490.3 0.00749 Jul-68 K.IGQQPQQPGAPPQQDYTK[136.11].A "sp|Q92945|FUBP2_HUMAN,tr|M0R0C6|M0R0C6_HUMAN,tr|M0QYG1|M0QYG1_HUMAN,tr|A0A087WTP3|A0A087WTP3_HUMAN" 4 1987.9843 1.48 129579 9490 3 1987.979537 663.6687 Far upstream element-binding protein 2 OS=Homo sapiens OX=9606 GN=KHSRP PE=1 SV=4 5.83 2053.3 - 78990 - - - -2.3979 - 1.539 0.266 - 47.4 1 2 0 -0.0048 18 0 0 0 9.80E+06 6.64E+06 - - - 2.5779 0.9988 221125_WJC_METTL3_EV_vs_WT_F09.09492.09492.3 0.127 Jun-68 K.IGQQPQQPGAPPQQDYTK.A "sp|Q92945|FUBP2_HUMAN,tr|M0R0C6|M0R0C6_HUMAN,tr|M0QYG1|M0QYG1_HUMAN,tr|A0A087WTP3|A0A087WTP3_HUMAN" 4 1979.9701 1.39 129581 9492 3 1979.971589 660.9973 Far upstream element-binding protein 2 OS=Homo sapiens OX=9606 GN=KHSRP PE=1 SV=4 5.83 2053.6 - 91461.6 - - - 0.75 - 1.479 0.34 - 30.6 2 2 0 0.0015 18 0 0 0 1.01E+07 7.26E+06 - - - 3.1655 0.9993 221125_WJC_METTL3_EV_vs_WT_F09.09496.09496.3 0.00355 Sep-44 R.TLVAVKPDGVQR.R "sp|O00746|NDKM_HUMAN,tr|Q4TT34|Q4TT34_HUMAN,tr|A0A087WVT9|A0A087WVT9_HUMAN,tr|H0Y6J0|H0Y6J0_HUMAN,tr|F2Z2X0|F2Z2X0_HUMAN" 5 1281.7405 0.99 129583 9496 3 1281.742544 428.2541 "Nucleoside diphosphate kinase, mitochondrial OS=Homo sapiens OX=9606 GN=NME4 PE=1 SV=1" 8.41 2054.1 - 179921 - - - 1.6064 - 1.626 0.362 - 84.3 1 2 0 0.0021 12 0 0 0 1.88E+07 1.90E+07 - - - 3.9228 0.9849 221125_WJC_METTL3_EV_vs_WT_F09.09497.09497.2 0.172 Mar-38 K.ALTSETNGTDSNGSNSSNIQ.- "sp|Q08209|PP2BA_HUMAN,tr|E7ETC2|E7ETC2_HUMAN" 2 1995.8617 - 129584 9497 2 1995.86509 998.9381 Serine\threonine-protein phosphatase 2B catalytic subunit alpha isoform OS=Homo sapiens OX=9606 GN=PPP3CA PE=1 SV=1 3.67 2054.2 - 56230.1 - - - 1.681 - 0.862 0.284 - 16 1 2 0 0.0034 20 0 0 0 - - - - - 0.7725 0.9965 221125_WJC_METTL3_EV_vs_WT_F09.09514.09514.2 0.0315 16-Jun K.VTMQNLNDR.L "sp|P13645|K1C10_HUMAN,sp|Q7Z3Z0|K1C25_HUMAN,sp|Q7Z3Y9|K1C26_HUMAN,sp|P02533|K1C14_HUMAN,sp|Q7Z3Y8|K1C27_HUMAN,sp|P08779|K1C16_HUMAN,sp|Q7Z3Y7|K1C28_HUMAN,tr|A0A1B0GVI3|A0A1B0GVI3_HUMAN" 8 1089.5237 264.96 129595 9514 2 1089.524546 545.7691 "Keratin, type I cytoskeletal 10 OS=Homo sapiens OX=9606 GN=KRT10 PE=1 SV=6" 5.81 2056.6 - 69640 - - - 0.7838 - 1.143 0.281 - 108.5 1 2 0 0.0009 9 0 0 0 6.56E+06 2.47E+04 - - - 1.5029 1 221125_WJC_METTL3_EV_vs_WT_F09.09518.09518.3 1.08E-06 Dec-52 K.K[136.11]GPGEVAGTVTGQK[136.11].R "sp|Q86U44|MTA70_HUMAN,tr|F5H6D8|F5H6D8_HUMAN,tr|H0YFV6|H0YFV6_HUMAN,tr|B4DTN4|B4DTN4_HUMAN" 4 1343.738 0.06 129598 9518 3 1343.739894 448.9199 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 8.59 2057.1 - 350903 - - - 1.4251 - 2.717 0.52 - 254.2 1 2 0 0.0019 14 0 0 0 1.11E+06 1.98E+07 - - - 6.9932 1 221125_WJC_METTL3_EV_vs_WT_F09.09536.09536.3 6.71E-06 15/56 K.KITESVAETAQTIKK.S sp|Q96A49|SYAP1_HUMAN 1 1645.9251 1.26 129607 9536 3 1645.928587 549.649 Synapse-associated protein 1 OS=Homo sapiens OX=9606 GN=SYAP1 PE=1 SV=1 8.5 2059.5 - 411753 - - - 2.1483 - 2.41 0.574 - 245.3 1 2 0 0.0035 15 0 0 0 4.84E+08 3.85E+08 - - - 7.2338 1 221125_WJC_METTL3_EV_vs_WT_F09.09543.09543.3 9.77E-11 20/56 K.K[136.11]ITESVAETAQTIK[136.11]K[136.11].S sp|Q96A49|SYAP1_HUMAN 1 1669.9677 1.26 129611 9543 3 1669.971112 557.6632 Synapse-associated protein 1 OS=Homo sapiens OX=9606 GN=SYAP1 PE=1 SV=1 8.5 2060.5 - 1.08E+06 - - - 2.0725 - 3.449 0.652 - 510.4 1 2 0 0.0035 15 0 0 0 4.83E+08 3.85E+08 - - - 9.0388 0.9997 221125_WJC_METTL3_EV_vs_WT_F09.09548.09548.3 4.09E-07 17/52 K.TSLTVADKIEDQKK.E "sp|P52732|KIF11_HUMAN,tr|A0A7I2V3A9|A0A7I2V3A9_HUMAN" 2 1574.8516 4.46 129614 9548 3 1574.855561 525.9578 Kinesin-like protein KIF11 OS=Homo sapiens OX=9606 GN=KIF11 PE=1 SV=2 5.79 2061.2 - 946687 - - - 2.5456 - 3.452 0.459 - 534.2 1 2 1 0.004 14 0 0 0 2.07E+08 4.65E+07 - - - 6.9488 0.9998 221125_WJC_METTL3_EV_vs_WT_F09.09549.09549.4 0.000797 14/78 K.TSLTVADKIEDQKK.E "sp|P52732|KIF11_HUMAN,tr|A0A7I2V3A9|A0A7I2V3A9_HUMAN" 2 1574.8516 4.64 129615 9549 4 1574.853914 394.7202 Kinesin-like protein KIF11 OS=Homo sapiens OX=9606 GN=KIF11 PE=1 SV=2 5.79 2061.3 - 765033 - - - 1.4998 - 2.643 0.463 - 126.1 1 2 1 0.0024 14 0 0 0 1.43E+08 3.09E+07 - - - 3.609 1 221125_WJC_METTL3_EV_vs_WT_F09.09556.09556.4 2.97E-07 17/84 K.KITESVAETAQTIKK.S sp|Q96A49|SYAP1_HUMAN 1 1645.9251 1.19 129620 9556 4 1645.925668 412.4885 Synapse-associated protein 1 OS=Homo sapiens OX=9606 GN=SYAP1 PE=1 SV=1 8.5 2062.3 - 730089 - - - 0.3749 - 2.877 0.561 - 173.9 1 2 0 0.0006 15 0 0 0 7.52E+07 6.30E+07 - - - 4.4869 0.9995 221125_WJC_METTL3_EV_vs_WT_F09.09557.09557.4 0.000208 14/78 K.TSLTVADK[136.11]IEDQK[136.11]K[136.11].E "sp|P52732|KIF11_HUMAN,tr|A0A7I2V3A9|A0A7I2V3A9_HUMAN" 2 1598.8942 4.64 129621 9557 4 1598.895106 400.7308 Kinesin-like protein KIF11 OS=Homo sapiens OX=9606 GN=KIF11 PE=1 SV=2 5.79 2062.4 - 382214 - - - 0.5967 - 2.545 0.405 - 119.1 1 2 1 0.001 14 0 0 0 1.43E+08 3.09E+07 - - - 3.0908 0.9997 221125_WJC_METTL3_EV_vs_WT_F09.09558.09558.3 0.000484 Sep-48 K.LHVGNISPTC[160.03]TNK[136.11].E "sp|Q9BWF3|RBM4_HUMAN,tr|D6R9K7|D6R9K7_HUMAN,tr|J3QRR5|J3QRR5_HUMAN,tr|E9PB51|E9PB51_HUMAN" 4 1447.7333 1.15 129622 9558 3 1447.734026 483.585 RNA-binding protein 4 OS=Homo sapiens OX=9606 GN=RBM4 PE=1 SV=1 8.23 2062.5 - 308162 - - - 0.5029 - 1.676 0.376 - 121.6 1 2 0 0.0007 13 0 0 0 8.24E+06 7.15E+06 - - - 4.132 0.9997 221125_WJC_METTL3_EV_vs_WT_F09.09559.09559.3 2.60E-06 Sep-48 R.C[160.03]SEQPSISDIKEK.S "sp|Q14527|HLTF_HUMAN,tr|A0A0C4DGA6|A0A0C4DGA6_HUMAN" 2 1519.7188 1.12 129623 9559 3 1519.722255 507.5802 Helicase-like transcription factor OS=Homo sapiens OX=9606 GN=HLTF PE=1 SV=2 4.68 2062.7 - 220491 - - - 2.2583 - 1.947 0.546 - 114.4 1 2 1 0.0034 13 0 0 0 3.55E+07 3.18E+07 - - - 6.4329 0.9367 221125_WJC_METTL3_EV_vs_WT_F09.09560.09560.4 0.0984 6/102 K.LSPSTSGPHSHDYLPQER[166.11].E "sp|Q9HCE1|MOV10_HUMAN,tr|Q5JR04|Q5JR04_HUMAN" 2 2016.9529 1.15 129624 9560 4 2016.952781 505.2455 Helicase MOV-10 OS=Homo sapiens OX=9606 GN=MOV10 PE=1 SV=2 5.99 2062.8 - 217082 - - - -0.0526 - 1.292 0.141 - 14.3 1 2 0 -0.0001 18 0 0 0 6.04E+06 5.25E+06 - - - 0.541 0.9991 221125_WJC_METTL3_EV_vs_WT_F09.09562.09562.3 0.000485 Aug-60 R.QQAEIKDTTLEENNVK.L "sp|Q3V6T2|GRDN_HUMAN,tr|A0A2R8YDS8|A0A2R8YDS8_HUMAN,tr|A0A2U3TZV9|A0A2U3TZV9_HUMAN,tr|H7C2C6|H7C2C6_HUMAN,tr|A0A2R8Y820|A0A2R8Y820_HUMAN,tr|A0A2R8Y885|A0A2R8Y885_HUMAN,tr|A0A2R8Y7D4|A0A2R8Y7D4_HUMAN,tr|A0A2R8YG73|A0A2R8YG73_HUMAN,tr|A0A2R8YGU1|A0A2R8YGU1_HUMAN,tr|A0A2R8YCU9|A0A2R8YCU9_HUMAN,tr|A0A2R8Y4X4|A0A2R8Y4X4_HUMAN,tr|A0A2R8Y4W8|A0A2R8Y4W8_HUMAN,tr|A0A2R8Y7B1|A0A2R8Y7B1_HUMAN" 13 1858.9272 2.38 129626 9562 3 1858.929608 620.6497 Girdin OS=Homo sapiens OX=9606 GN=CCDC88A PE=1 SV=2 4.41 2063 - 124991 - - - 1.276 - 1.645 0.447 - 75.1 1 2 1 0.0024 16 0 0 0 4.93E+06 2.07E+06 - - - 4.8001 1 221125_WJC_METTL3_EV_vs_WT_F09.09566.09566.4 4.20E-06 16/84 K.K[136.11]ITESVAETAQTIK[136.11]K[136.11].S sp|Q96A49|SYAP1_HUMAN 1 1669.9677 1.19 129628 9566 4 1669.965446 418.4992 Synapse-associated protein 1 OS=Homo sapiens OX=9606 GN=SYAP1 PE=1 SV=1 8.5 2063.6 - 1.88E+06 - - - -1.3204 - 3.068 0.539 - 216.2 1 2 0 -0.0022 15 0 0 0 7.50E+07 6.30E+07 - - - 4.318 1 221125_WJC_METTL3_EV_vs_WT_F09.09570.09570.3 1.15E-08 16/52 K.HQALQAEIAGHEPR.L "sp|Q13813|SPTN1_HUMAN,tr|A0A0D9SF54|A0A0D9SF54_HUMAN,tr|A0A0D9SGF6|A0A0D9SGF6_HUMAN" 3 1555.7855 1.12 129632 9570 3 1555.786834 519.6025 "Spectrin alpha chain, non-erythrocytic 1 OS=Homo sapiens OX=9606 GN=SPTAN1 PE=1 SV=3" 6 2064.1 - 259995 - - - 0.833 - 2.978 0.596 - 262.6 1 2 0 0.0013 14 0 0 0 1.40E+07 1.24E+07 - - - 8.0845 0.9997 221125_WJC_METTL3_EV_vs_WT_F09.09571.09571.2 0.00213 28-Sep K.KITESVAETAQTIKK.S sp|Q96A49|SYAP1_HUMAN 1 1645.9251 1.36 129633 9571 2 1645.925619 823.9698 Synapse-associated protein 1 OS=Homo sapiens OX=9606 GN=SYAP1 PE=1 SV=1 8.5 2064.2 - 145656 - - - 0.3451 - 1.823 0.442 - 175.4 1 2 0 0.0006 15 0 0 0 9.19E+06 6.77E+06 - - - 3.7817 1 221125_WJC_METTL3_EV_vs_WT_F09.09577.09577.3 2.50E-08 17/48 R.C[160.03]SEQPSISDIK[136.11]EK[136.11].S "sp|Q14527|HLTF_HUMAN,tr|A0A0C4DGA6|A0A0C4DGA6_HUMAN" 2 1535.7472 1.18 129637 9577 3 1535.746671 512.923 Helicase-like transcription factor OS=Homo sapiens OX=9606 GN=HLTF PE=1 SV=2 4.68 2065 - 453630 - - - -0.3594 - 3.404 0.611 - 460.4 1 2 1 -0.0006 13 0 0 0 4.12E+07 3.49E+07 - - - 8.6731 1 221125_WJC_METTL3_EV_vs_WT_F09.09578.09578.3 8.00E-10 Dec-44 R.DHANEELDELKR.K sp|Q14789|GOGB1_HUMAN 1 1467.6954 1.44 129638 9578 3 1467.694439 490.2391 Golgin subfamily B member 1 OS=Homo sapiens OX=9606 GN=GOLGB1 PE=1 SV=2 4.5 2065.2 - 320004 - - - -0.6452 - 2.611 0.604 - 314.2 1 2 0 -0.0009 12 0 0 0 7.22E+06 5.00E+06 - - - 7.934 1 221125_WJC_METTL3_EV_vs_WT_F09.09579.09579.2 2.27E-07 15/28 K.K[136.11]ITESVAETAQTIK[136.11]K[136.11].S sp|Q96A49|SYAP1_HUMAN 1 1669.9677 1.36 129639 9579 2 1669.965835 835.9911 Synapse-associated protein 1 OS=Homo sapiens OX=9606 GN=SYAP1 PE=1 SV=1 8.5 2065.3 - 195663 - - - -1.0874 - 3.303 0.632 - 449.9 1 2 0 -0.0018 15 0 0 0 9.19E+06 6.77E+06 - - - 6.6459 0.9069 221125_WJC_METTL3_EV_vs_WT_F09.09580.09580.3 9.36E-05 Sep-72 G.VHQSVATDGPSSTQPALPK[136.11].A "sp|O75251|NDUS7_HUMAN,tr|F5H5N1|F5H5N1_HUMAN,tr|A0A087WTI3|A0A087WTI3_HUMAN,tr|A0A087WXF6|A0A087WXF6_HUMAN" 4 1926.9891 1.07 129640 9580 3 1926.984585 643.337 "NADH dehydrogenase [ubiquinone] iron-sulfur protein 7, mitochondrial OS=Homo sapiens OX=9606 GN=NDUFS7 PE=1 SV=3" 6.71 2065.4 - 187934 - - - -2.3197 - 1.809 0.354 - 77.5 1 1 0 -0.0045 19 0 0 0 1.92E+07 1.80E+07 - - - 3.9418 1 221125_WJC_METTL3_EV_vs_WT_F09.09587.09587.3 1.25E-06 13/96 K.VASTLTEEGGGGGGGGGSVAPK[136.11]PPR[166.11].G "sp|Q8TF68|ZN384_HUMAN,tr|F5H105|F5H105_HUMAN,tr|F5H8L7|F5H8L7_HUMAN,tr|A0A804HJE2|A0A804HJE2_HUMAN,tr|E9PHB3|E9PHB3_HUMAN" 5 2212.1203 1.5 129645 9587 3 2212.116974 738.3807 Zinc finger protein 384 OS=Homo sapiens OX=9606 GN=ZNF384 PE=1 SV=2 6.11 2066.3 - 177845 - - - -1.5008 - 2.291 0.539 - 133.1 1 2 0 -0.0033 25 0 0 0 6.20E+06 4.12E+06 - - - 6.4556 0.9964 221125_WJC_METTL3_EV_vs_WT_F09.09589.09589.2 5.96E-05 26-Sep K.TSLTVADKIEDQKK.E "sp|P52732|KIF11_HUMAN,tr|A0A7I2V3A9|A0A7I2V3A9_HUMAN" 2 1574.8516 999 129647 9589 2 1574.849993 788.4331 Kinesin-like protein KIF11 OS=Homo sapiens OX=9606 GN=KIF11 PE=1 SV=2 5.79 2066.6 - 131425 - - - -0.9899 - 1.848 0.424 - 211.5 1 2 1 -0.0016 14 0 0 0 3.78E+06 0.00E+00 - - - 3.7132 1 221125_WJC_METTL3_EV_vs_WT_F09.09594.09594.3 7.77E-06 15/56 K.K[136.11]ITESVAETAQTIKK[136.11].S sp|Q96A49|SYAP1_HUMAN 1 1661.9535 - 129650 9594 3 1661.950473 554.9918 Synapse-associated protein 1 OS=Homo sapiens OX=9606 GN=SYAP1 PE=1 SV=1 8.5 2067.2 - 1.04E+06 - - - -1.7919 - 3.221 0.448 - 243.5 2 2 0 -0.003 15 0 0 0 - - - - - 6.4468 0.9996 221125_WJC_METTL3_EV_vs_WT_F09.09595.09595.3 0.000352 Dec-60 R.R[166.11]ELEIESQTEEQPTTK[136.11].Q sp|Q9NYH9|UTP6_HUMAN 1 1934.9552 2.01 129651 9595 3 1934.948268 645.9923 U3 small nucleolar RNA-associated protein 6 homolog OS=Homo sapiens OX=9606 GN=UTP6 PE=1 SV=2 4.33 2067.3 - 380570 - - - -3.5748 - 2.299 0.439 - 220 1 2 0 -0.0069 16 0 0 0 7.42E+06 3.70E+06 - - - 5.5685 0.9998 221125_WJC_METTL3_EV_vs_WT_F09.09602.09602.3 1.81E-05 Dec-56 K.GAVDGGLSIPHSTK[136.11]R[166.11].F "sp|P46777|RL5_HUMAN,tr|A0A2R8Y6J3|A0A2R8Y6J3_HUMAN,tr|Q5T7N0|Q5T7N0_HUMAN" 3 1511.8175 0.64 129655 9602 3 1511.813388 504.9464 60S ribosomal protein L5 OS=Homo sapiens OX=9606 GN=RPL5 PE=1 SV=3 8.75 2068.2 - 334263 - - - -2.7265 - 2.166 0.465 - 157.2 1 2 0 -0.0041 15 0 0 0 5.68E+06 8.81E+06 - - - 5.7399 0.9998 221125_WJC_METTL3_EV_vs_WT_F09.09607.09607.3 5.94E-05 14/68 R.ITHQIVDR[166.11]PGQQTSVIGR[166.11].C "sp|O00541|PESC_HUMAN,tr|B3KXD6|B3KXD6_HUMAN,tr|B5MCF9|B5MCF9_HUMAN" 3 2024.103 0.63 129659 9607 3 2024.099028 675.7083 Pescadillo homolog OS=Homo sapiens OX=9606 GN=PES1 PE=1 SV=1 9.61 2068.8 - 302426 - - - -1.9678 - 2.176 0.429 - 218.8 1 2 0 -0.004 18 0 0 0 1.26E+07 2.00E+07 - - - 5.2578 0.9998 221125_WJC_METTL3_EV_vs_WT_F09.09609.09609.3 8.31E-05 Nov-56 K.GAVDGGLSIPHSTKR.F "sp|P46777|RL5_HUMAN,tr|A0A2R8Y6J3|A0A2R8Y6J3_HUMAN,tr|Q5T7N0|Q5T7N0_HUMAN" 3 1493.795 0.63 129660 9609 3 1493.790646 498.939 60S ribosomal protein L5 OS=Homo sapiens OX=9606 GN=RPL5 PE=1 SV=3 8.75 2069 - 197449 - - - -2.9415 - 2.382 0.432 - 124.5 1 2 0 -0.0044 15 0 0 0 5.68E+06 8.95E+06 - - - 5.6199 0.9818 221125_WJC_METTL3_EV_vs_WT_F09.09610.09610.3 0.0285 May-72 K.VSESEGK[136.11]LEGQATAVTPNK[136.11].N sp|Q9BXB4|OSB11_HUMAN 1 1960.0084 1.35 129661 9610 3 1960.009292 654.3434 Oxysterol-binding protein-related protein 11 OS=Homo sapiens OX=9606 GN=OSBPL11 PE=1 SV=2 4.79 2069.1 - 152890 - - - 0.4551 - 1.13 0.317 - 21.7 1 2 1 0.0009 19 0 0 0 3.37E+06 2.49E+06 - - - 2.3743 0.9999 221125_WJC_METTL3_EV_vs_WT_F09.09615.09615.3 0.000526 Oct-76 K.TPPPRPSPLEAGSDGC[160.03]EEPK.Q sp|Q9BUA3|SPNDC_HUMAN 1 2119.9844 4.75 129664 9615 3 2119.982466 707.6688 Spindlin interactor and repressor of chromatin-binding protein OS=Homo sapiens OX=9606 GN=SPINDOC PE=1 SV=3 4.41 2069.8 - 372780 - - - -0.9283 - 1.945 0.509 - 82.4 1 2 0 -0.002 20 0 0 0 1.82E+07 3.82E+06 - - - 5.8282 0.9999 221125_WJC_METTL3_EV_vs_WT_F09.09616.09616.4 1.18E-05 18/102 R.ITHQIVDR[166.11]PGQQTSVIGR[166.11].C "sp|O00541|PESC_HUMAN,tr|B3KXD6|B3KXD6_HUMAN,tr|B5MCF9|B5MCF9_HUMAN" 3 2024.103 0.63 129665 9616 4 2024.101592 507.033 Pescadillo homolog OS=Homo sapiens OX=9606 GN=PES1 PE=1 SV=1 9.61 2069.9 - 652299 - - - -0.7011 - 3.095 0.416 - 275.3 1 2 0 -0.0014 18 0 0 0 2.14E+07 3.38E+07 - - - 3.2335 0.9997 221125_WJC_METTL3_EV_vs_WT_F09.09617.09617.3 1.39E-05 16/48 R.FREDHPDLIQNAK.K "sp|P17480|UBF1_HUMAN,tr|E9PKP7|E9PKP7_HUMAN" 2 1581.79 1.52 129666 9617 3 1581.788592 528.2706 Nucleolar transcription factor 1 OS=Homo sapiens OX=9606 GN=UBTF PE=1 SV=1 5.38 2070 - 285095 - - - -0.8617 - 2.238 0.455 - 311.1 1 2 1 -0.0014 13 0 0 0 1.11E+07 7.32E+06 - - - 5.7966 0.999 221125_WJC_METTL3_EV_vs_WT_F09.09620.09620.3 3.65E-09 15/72 G.VHQSVATDGPSSTQPALPK.A "sp|O75251|NDUS7_HUMAN,tr|F5H5N1|F5H5N1_HUMAN,tr|A0A087WTI3|A0A087WTI3_HUMAN,tr|A0A087WXF6|A0A087WXF6_HUMAN" 4 1918.9749 1.07 129667 9620 3 1918.97645 640.6656 "NADH dehydrogenase [ubiquinone] iron-sulfur protein 7, mitochondrial OS=Homo sapiens OX=9606 GN=NDUFS7 PE=1 SV=3" 6.71 2070.5 - 319544 - - - 0.8312 - 3.17 0.63 - 255.2 1 1 0 0.0016 19 0 0 0 1.92E+07 1.80E+07 - - - 8.3979 1 221125_WJC_METTL3_EV_vs_WT_F09.09622.09622.3 3.23E-08 19/64 K.QQSIAGSADSK[136.11]PIDVSR[166.11].L "sp|Q12904|AIMP1_HUMAN,tr|A0A804HJ47|A0A804HJ47_HUMAN,tr|A0A5F9ZHC5|A0A5F9ZHC5_HUMAN" 3 1775.9133 1.31 129669 9622 3 1775.911229 592.9784 Aminoacyl tRNA synthase complex-interacting multifunctional protein 1 OS=Homo sapiens OX=9606 GN=AIMP1 PE=1 SV=2 5.96 2070.8 - 472511 - - - -1.1442 - 3.08 0.623 - 360.8 1 2 0 -0.002 17 0 0 0 1.28E+08 9.83E+07 - - - 8.3272 1 221125_WJC_METTL3_EV_vs_WT_F09.09623.09623.3 3.31E-05 13/68 R.ITHQIVDRPGQQTSVIGR.C "sp|O00541|PESC_HUMAN,tr|B3KXD6|B3KXD6_HUMAN,tr|B5MCF9|B5MCF9_HUMAN" 3 2004.0865 0.63 129670 9623 3 2004.087656 669.0361 Pescadillo homolog OS=Homo sapiens OX=9606 GN=PES1 PE=1 SV=1 9.61 2070.9 - 384725 - - - 0.5913 - 2.83 0.519 - 187 1 2 0 0.0012 18 0 0 0 1.26E+07 2.00E+07 - - - 6.9164 0.9985 221125_WJC_METTL3_EV_vs_WT_F09.09625.09625.3 0.00163 Jul-40 R.RPVHLDQAAFR.T sp|Q9H0D6|XRN2_HUMAN 1 1308.7051 1.04 129672 9625 3 1308.699621 437.2423 5'-3' exoribonuclease 2 OS=Homo sapiens OX=9606 GN=XRN2 PE=1 SV=1 9.61 2071.2 - 109973 - - - -4.1889 - 1.621 0.433 - 71 1 2 0 -0.0055 11 0 0 0 2.40E+06 2.31E+06 - - - 4.7382 1 221125_WJC_METTL3_EV_vs_WT_F09.09628.09628.4 1.72E-07 17/102 R.ITHQIVDRPGQQTSVIGR.C "sp|O00541|PESC_HUMAN,tr|B3KXD6|B3KXD6_HUMAN,tr|B5MCF9|B5MCF9_HUMAN" 3 2004.0865 0.63 129673 9628 4 2004.084873 502.0289 Pescadillo homolog OS=Homo sapiens OX=9606 GN=PES1 PE=1 SV=1 9.61 2071.6 - 719171 - - - -0.7974 - 3.161 0.491 - 244.2 1 2 0 -0.0016 18 0 0 0 2.14E+07 3.38E+07 - - - 3.8935 1 221125_WJC_METTL3_EV_vs_WT_F09.09629.09629.3 2.05E-10 22/64 K.QQSIAGSADSKPIDVSR.L "sp|Q12904|AIMP1_HUMAN,tr|A0A804HJ47|A0A804HJ47_HUMAN,tr|A0A5F9ZHC5|A0A5F9ZHC5_HUMAN" 3 1757.8908 1.31 129674 9629 3 1757.89125 586.9709 Aminoacyl tRNA synthase complex-interacting multifunctional protein 1 OS=Homo sapiens OX=9606 GN=AIMP1 PE=1 SV=2 5.96 2071.7 - 970976 - - - 0.2611 - 3.702 0.591 - 537.8 1 2 0 0.0005 17 0 0 0 1.28E+08 9.83E+07 - - - 8.4355 0.9998 221125_WJC_METTL3_EV_vs_WT_F09.09630.09630.2 0.00139 20-Jul R.VEIIANDQGNR[166.11].L "sp|P11021|BIP_HUMAN,sp|P48741|HSP77_HUMAN,sp|P54652|HSP72_HUMAN,sp|P0DMV8|HS71A_HUMAN,sp|P34931|HS71L_HUMAN,sp|P11142|HSP7C_HUMAN,sp|P0DMV9|HS71B_HUMAN,sp|P17066|HSP76_HUMAN,tr|E9PQQ4|E9PQQ4_HUMAN,tr|E9PNE6|E9PNE6_HUMAN,tr|E9PKE3|E9PKE3_HUMAN,tr|A0A7P0TB36|A0A7P0TB36_HUMAN,tr|E9PLF4|E9PLF4_HUMAN,tr|A0A7P0TAI0|A0A7P0TAI0_HUMAN,tr|Q53FA3|Q53FA3_HUMAN,tr|E9PI65|E9PI65_HUMAN,tr|E9PK54|E9PK54_HUMAN,tr|E9PN25|E9PN25_HUMAN,tr|E9PPY6|E9PPY6_HUMAN,tr|E9PQK7|E9PQK7_HUMAN,tr|A0A0G2JIW1|A0A0G2JIW1_HUMAN" 21 1237.629 0.13 129675 9630 2 1237.629296 619.8218 Endoplasmic reticulum chaperone BiP OS=Homo sapiens OX=9606 GN=HSPA5 PE=1 SV=2 4.37 2071.8 - 347919 - - - 0.2117 - 1.787 0.446 - 145 1 2 0 0.0003 11 0 0 0 2.13E+06 1.64E+07 - - - 3.9056 1 221125_WJC_METTL3_EV_vs_WT_F09.09640.09640.3 4.35E-08 15/64 K.SVASGGWQEPENPHTQR.M "sp|Q9UJW0|DCTN4_HUMAN,tr|E5RGG1|E5RGG1_HUMAN,tr|H9KVE0|H9KVE0_HUMAN" 3 1878.8609 1.35 129681 9640 3 1878.860018 627.2942 Dynactin subunit 4 OS=Homo sapiens OX=9606 GN=DCTN4 PE=1 SV=1 5.38 2073.1 - 437819 - - - -0.463 - 2.908 0.61 - 194.8 1 2 0 -0.0009 17 0 0 0 1.38E+07 1.02E+07 - - - 8.0374 1 221125_WJC_METTL3_EV_vs_WT_F09.09644.09644.3 3.29E-07 Nov-64 R.SAGPSDHIDSSVTGVQR.F sp|O75113|N4BP1_HUMAN 1 1711.8125 0.62 129683 9644 3 1711.813656 571.6115 NEDD4-binding protein 1 OS=Homo sapiens OX=9606 GN=N4BP1 PE=1 SV=4 5.19 2073.6 - 145721 - - - 0.6514 - 2.339 0.622 - 152.7 1 2 0 0.0011 17 0 0 0 2.27E+06 3.67E+06 - - - 7.621 0.9999 221125_WJC_METTL3_EV_vs_WT_F09.09652.09652.3 0.000201 Dec-48 K.QELQEQLDLQHKK.C sp|Q9Y6D9|MD1L1_HUMAN 1 1635.858 2.66 129689 9652 3 1635.860901 546.2933 Mitotic spindle assembly checkpoint protein MAD1 OS=Homo sapiens OX=9606 GN=MAD1L1 PE=1 SV=2 5.45 2074.6 - 365717 - - - 1.7526 - 2.468 0.403 - 217.9 1 2 0 0.0029 13 0 0 0 9.98E+06 3.75E+06 - - - 5.4817 1 221125_WJC_METTL3_EV_vs_WT_F09.09655.09655.3 2.82E-06 15/64 K.SVASGGWQEPENPHTQR[166.11].M "sp|Q9UJW0|DCTN4_HUMAN,tr|E5RGG1|E5RGG1_HUMAN,tr|H9KVE0|H9KVE0_HUMAN" 3 1888.8692 1.34 129692 9655 3 1888.870239 630.6303 Dynactin subunit 4 OS=Homo sapiens OX=9606 GN=DCTN4 PE=1 SV=1 5.38 2074.9 - 466763 - - - 0.5723 - 2.75 0.611 - 224.3 1 2 0 0.0011 17 0 0 0 1.38E+07 1.03E+07 - - - 7.9074 1 221125_WJC_METTL3_EV_vs_WT_F09.09659.09659.3 9.60E-08 13/60 R.TGSISSSVSVPAK[136.11]PER[166.11].R "sp|Q6PJT7|ZC3HE_HUMAN,tr|G3V256|G3V256_HUMAN,tr|H0YJ87|H0YJ87_HUMAN,tr|G3V5I6|G3V5I6_HUMAN,tr|H0YJA2|H0YJA2_HUMAN" 5 1618.8645 1.19 129694 9659 3 1618.865205 540.6288 Zinc finger CCCH domain-containing protein 14 OS=Homo sapiens OX=9606 GN=ZC3H14 PE=1 SV=1 8.41 2075.5 - 1.52E+06 - - - 0.4231 - 2.907 0.561 - 150.1 1 2 0 0.0007 16 0 0 0 5.93E+07 5.00E+07 - - - 7.5325 0.999 221125_WJC_METTL3_EV_vs_WT_F09.09661.09661.4 0.00303 13/72 K.QELQEQLDLQHK[136.11]K[136.11].C sp|Q9Y6D9|MD1L1_HUMAN 1 1651.8864 2.19 129696 9661 4 1651.888689 413.9789 Mitotic spindle assembly checkpoint protein MAD1 OS=Homo sapiens OX=9606 GN=MAD1L1 PE=1 SV=2 5.45 2075.7 - 312497 - - - 1.3651 - 2.144 0.298 - 193.7 1 2 0 0.0023 13 0 0 0 8.34E+06 3.81E+06 - - - 2.1019 1 221125_WJC_METTL3_EV_vs_WT_F09.09664.09664.2 4.76E-08 Oct-32 K.QQSIAGSADSKPIDVSR.L "sp|Q12904|AIMP1_HUMAN,tr|A0A804HJ47|A0A804HJ47_HUMAN,tr|A0A5F9ZHC5|A0A5F9ZHC5_HUMAN" 3 1757.8908 1.45 129699 9664 2 1757.887867 879.9527 Aminoacyl tRNA synthase complex-interacting multifunctional protein 1 OS=Homo sapiens OX=9606 GN=AIMP1 PE=1 SV=2 5.96 2076.1 - 63108.8 - - - -1.6634 - 2.287 0.677 - 261.3 1 2 0 -0.0029 17 0 0 0 2.19E+06 1.51E+06 - - - 6.0742 0.996 221125_WJC_METTL3_EV_vs_WT_F09.09671.09671.4 0.191 Oct-84 K.LTGVFAPR[166.11]PSTGPHK[136.11].L "sp|P62701|RS4X_HUMAN,sp|P22090|RS4Y1_HUMAN,sp|Q8TD47|RS4Y2_HUMAN,tr|C9JEH7|C9JEH7_HUMAN" 4 1581.8746 0.9 129704 9671 4 1581.876223 396.4759 "40S ribosomal protein S4, X isoform OS=Homo sapiens OX=9606 GN=RPS4X PE=1 SV=2" 11 2077 - 285558 - - - 1.0064 - 1.623 0.242 - 58.5 1 2 0 0.0016 15 0 0 0 4.94E+06 5.51E+06 - - - 1.5052 0.9985 221125_WJC_METTL3_EV_vs_WT_F09.09672.09672.3 0.00236 Sep-68 K.ESR[166.11]PGLVTVTSSQSTPAK[136.11].A "sp|Q9NZJ0|DTL_HUMAN,tr|F5GZ90|F5GZ90_HUMAN" 2 1861.9864 0.56 129705 9672 3 1861.993405 621.6694 Denticleless protein homolog OS=Homo sapiens OX=9606 GN=DTL PE=1 SV=3 8.85 2077.1 - 276364 - - - 3.7481 - 2.212 0.356 - 90.2 1 2 0 0.007 18 0 0 0 5.13E+06 9.21E+06 - - - 4.484 0.9999 221125_WJC_METTL3_EV_vs_WT_F09.09677.09677.2 1.49E-06 Sep-32 K.QQSIAGSADSK[136.11]PIDVSR[166.11].L "sp|Q12904|AIMP1_HUMAN,tr|A0A804HJ47|A0A804HJ47_HUMAN,tr|A0A5F9ZHC5|A0A5F9ZHC5_HUMAN" 3 1775.9133 1.45 129708 9677 2 1775.91297 888.9639 Aminoacyl tRNA synthase complex-interacting multifunctional protein 1 OS=Homo sapiens OX=9606 GN=AIMP1 PE=1 SV=2 5.96 2077.8 - 76507.5 - - - -0.1639 - 1.871 0.604 - 223.6 1 2 0 -0.0003 17 0 0 0 2.19E+06 1.51E+06 - - - 5.0423 0.9918 221125_WJC_METTL3_EV_vs_WT_F09.09682.09682.4 7.26E-10 20/126 F.ASSLVSGLNSSASEPAK[136.11]EPAK[136.11]K[136.11].S "sp|Q86U44|MTA70_HUMAN,tr|F5H6D8|F5H6D8_HUMAN,tr|H0YFV6|H0YFV6_HUMAN,tr|B4DTN4|B4DTN4_HUMAN" 4 2181.1703 0.72 129711 9682 4 2181.172058 546.2999 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 8.54 2078.4 - 966032 - - - 0.7936 - 3.692 0.567 - 307.8 1 1 1 0.0017 22 0 0 0 1.31E+07 1.81E+07 - - - 4.5881 1 221125_WJC_METTL3_EV_vs_WT_F09.09683.09683.3 5.48E-07 Nov-68 K.ESRPGLVTVTSSQSTPAK.A "sp|Q9NZJ0|DTL_HUMAN,tr|F5GZ90|F5GZ90_HUMAN" 2 1843.964 0.56 129712 9683 3 1843.965669 615.6619 Denticleless protein homolog OS=Homo sapiens OX=9606 GN=DTL PE=1 SV=3 8.85 2078.6 - 252906 - - - 0.929 - 2.919 0.468 - 131.7 1 2 0 0.0017 18 0 0 0 5.13E+06 9.11E+06 - - - 6.4248 0.9993 221125_WJC_METTL3_EV_vs_WT_F09.09684.09684.3 0.0037 Oct-56 K.LTGVFAPR[166.11]PSTGPHK[136.11].L "sp|P62701|RS4X_HUMAN,sp|P22090|RS4Y1_HUMAN,sp|Q8TD47|RS4Y2_HUMAN,tr|C9JEH7|C9JEH7_HUMAN" 4 1581.8746 0.95 129713 9684 3 1581.875784 528.2988 "40S ribosomal protein S4, X isoform OS=Homo sapiens OX=9606 GN=RPS4X PE=1 SV=2" 11 2078.7 - 213879 - - - 0.7289 - 1.827 0.311 - 100.3 1 2 0 0.0012 15 0 0 0 3.04E+06 3.20E+06 - - - 3.5796 0.9855 221125_WJC_METTL3_EV_vs_WT_F09.09690.09690.4 0.0319 Nov-84 R.YEHALSQC[160.03]SVDVYK[136.11]K[136.11].V "sp|Q14203|DCTN1_HUMAN,tr|A0A804CDA6|A0A804CDA6_HUMAN,tr|E7EX90|E7EX90_HUMAN,tr|A0A7P0Z4C3|A0A7P0Z4C3_HUMAN,tr|Q6AWB1|Q6AWB1_HUMAN" 5 1841.8953 1.86 129717 9690 4 1841.899315 461.4811 Dynactin subunit 1 OS=Homo sapiens OX=9606 GN=DCTN1 PE=1 SV=3 6.74 2079.5 - 190582 - - - 2.188 - 1.351 0.219 - 75.3 1 2 0 0.004 15 0 0 0 1.43E+07 7.68E+06 - - - 1.2387 0.9995 221125_WJC_METTL3_EV_vs_WT_F09.09691.09691.3 2.84E-05 13/56 K.SNPVIPISSSNHSAR.S sp|O95628|CNOT4_HUMAN 1 1564.7958 0.91 129718 9691 3 1564.800963 522.6059 CCR4-NOT transcription complex subunit 4 OS=Homo sapiens OX=9606 GN=CNOT4 PE=1 SV=3 9.49 2079.6 - 189183 - - - 3.3199 - 1.997 0.429 - 167.2 1 2 0 0.0052 15 0 0 0 1.16E+07 1.28E+07 - - - 5.1262 0.9998 221125_WJC_METTL3_EV_vs_WT_F09.09698.09698.4 7.50E-05 15/84 R.YEHALSQC[160.03]SVDVYKK.V "sp|Q14203|DCTN1_HUMAN,tr|A0A804CDA6|A0A804CDA6_HUMAN,tr|E7EX90|E7EX90_HUMAN,tr|A0A7P0Z4C3|A0A7P0Z4C3_HUMAN,tr|Q6AWB1|Q6AWB1_HUMAN" 5 1825.8669 1.88 129723 9698 4 1825.872995 457.474 Dynactin subunit 1 OS=Homo sapiens OX=9606 GN=DCTN1 PE=1 SV=3 6.74 2080.5 - 554278 - - - 3.3464 - 2.743 0.483 - 199.7 1 2 0 0.0061 15 0 0 0 1.47E+07 7.81E+06 - - - 3.7894 0.9995 221125_WJC_METTL3_EV_vs_WT_F09.09701.09701.2 0.0132 20-Jul R.DSYDSYATHNE.- sp|Q14011|CIRBP_HUMAN 1 1300.4844 - 129726 9701 2 1300.48507 651.2495 Cold-inducible RNA-binding protein OS=Homo sapiens OX=9606 GN=CIRBP PE=1 SV=1 4.31 2080.9 - 106821 - - - 0.5229 - 1.122 0.52 - 77 1 2 0 0.0007 11 0 0 0 - - - - - 3.1929 1 221125_WJC_METTL3_EV_vs_WT_F09.09704.09704.3 8.38E-07 18/52 R.K[136.11]NPLPPSVGVVDK[136.11]K[136.11].E sp|Q8NC51|PAIRB_HUMAN 1 1500.909 0.78 129727 9704 3 1500.911346 501.3103 Plasminogen activator inhibitor 1 RNA-binding protein OS=Homo sapiens OX=9606 GN=SERBP1 PE=1 SV=2 9.7 2081.3 - 461690 - - - 1.5537 - 3.392 0.58 - 474.1 1 2 0 0.0023 14 0 0 0 2.22E+07 2.86E+07 - - - 8.2517 1 221125_WJC_METTL3_EV_vs_WT_F09.09705.09705.3 2.71E-07 Dec-56 R.YEHALSQC[160.03]SVDVYKK.V "sp|Q14203|DCTN1_HUMAN,tr|A0A804CDA6|A0A804CDA6_HUMAN,tr|E7EX90|E7EX90_HUMAN,tr|A0A7P0Z4C3|A0A7P0Z4C3_HUMAN,tr|Q6AWB1|Q6AWB1_HUMAN" 5 1825.8669 1.59 129728 9705 3 1825.87155 609.6296 Dynactin subunit 1 OS=Homo sapiens OX=9606 GN=DCTN1 PE=1 SV=3 6.74 2081.4 - 341690 - - - 2.555 - 2.651 0.586 - 212.1 1 2 0 0.0047 15 0 0 0 7.18E+06 4.52E+06 - - - 7.616 0.9999 221125_WJC_METTL3_EV_vs_WT_F09.09712.09712.3 0.00122 13/56 K.SNPVIPISSSNHSAR[166.11].S sp|O95628|CNOT4_HUMAN 1 1574.804 1.99 129733 9712 3 1574.807058 525.942 CCR4-NOT transcription complex subunit 4 OS=Homo sapiens OX=9606 GN=CNOT4 PE=1 SV=3 9.49 2082.4 - 282382 - - - 1.9177 - 2.194 0.483 - 201.2 1 2 0 0.003 15 0 0 0 1.05E+07 5.28E+06 - - - 5.9744 0.9881 221125_WJC_METTL3_EV_vs_WT_F09.09713.09713.3 2.29E-06 13/84 F.ASSLVSGLNSSASEPAK[136.11]EPAK[136.11]K[136.11].S "sp|Q86U44|MTA70_HUMAN,tr|F5H6D8|F5H6D8_HUMAN,tr|H0YFV6|H0YFV6_HUMAN,tr|B4DTN4|B4DTN4_HUMAN" 4 2181.1703 0.001 129734 9713 3 2181.172776 728.0641 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 8.54 2082.5 - 157884 - - - 1.1228 - 2.442 0.567 - 154.6 1 1 1 0.0024 22 0 0 0 0.00E+00 4.08E+06 - - - 6.9775 0.9956 221125_WJC_METTL3_EV_vs_WT_F09.09716.09716.2 0.0988 Mar-32 R.AQENYEGSEEVSPPQTK.D sp|Q93008|USP9X_HUMAN 1 1891.8436 5.29 129737 9716 2 1891.844401 946.9291 Probable ubiquitin carboxyl-terminal hydrolase FAF-X OS=Homo sapiens OX=9606 GN=USP9X PE=1 SV=4 4.09 2082.9 - 62434.1 - - - 0.4414 - 0.792 0.375 - 14.7 1 2 0 0.0008 17 0 0 0 1.57E+07 2.97E+06 - - - 1.2372 0.9971 221125_WJC_METTL3_EV_vs_WT_F09.09723.09723.3 0.000563 Aug-44 K.HHVPSDFNVNVK.V sp|Q9C075|K1C23_HUMAN 1 1391.6946 31.52 129742 9723 3 1391.698682 464.9055 "Keratin, type I cytoskeletal 23 OS=Homo sapiens OX=9606 GN=KRT23 PE=1 SV=2" 6.92 2083.8 - 193931 - - - 2.9346 - 1.437 0.353 - 73 1 2 0 0.0041 12 0 0 0 6.37E+06 2.02E+05 - - - 3.4794 0.9988 221125_WJC_METTL3_EV_vs_WT_F09.09724.09724.3 0.000252 Sep-64 K.TK[136.11]ENVNATENC[160.03]ISAVGK[136.11].L "sp|O00410|IPO5_HUMAN,tr|H0Y8C6|H0Y8C6_HUMAN" 2 1849.9175 0.66 129743 9724 3 1849.917558 617.6464 Importin-5 OS=Homo sapiens OX=9606 GN=IPO5 PE=1 SV=4 5.81 2083.9 - 155240 - - - 0.0438 - 1.722 0.395 - 103.9 1 2 1 0.0001 17 0 0 0 1.35E+06 2.03E+06 - - - 4.3168 0.9981 221125_WJC_METTL3_EV_vs_WT_F09.09726.09726.3 0.000441 May-76 K.EGEEPTVYSDEEEPK[136.11]DESAR[166.11].K sp|O00264|PGRC1_HUMAN 1 2312.9887 1.94 129745 9726 3 2312.992136 772.0035 Membrane-associated progesterone receptor component 1 OS=Homo sapiens OX=9606 GN=PGRMC1 PE=1 SV=3 3.89 2084.2 - 75808.1 - - - 1.4726 - 1.283 0.456 - 23.8 1 2 1 0.0034 20 0 0 0 1.39E+06 7.16E+05 - - - 4.2276 1 221125_WJC_METTL3_EV_vs_WT_F09.09731.09731.3 3.81E-11 15/76 K.EGEEPTVYSDEEEPKDESAR.K sp|O00264|PGRC1_HUMAN 1 2294.9663 1.87 129748 9731 3 2294.969956 765.996 Membrane-associated progesterone receptor component 1 OS=Homo sapiens OX=9606 GN=PGRMC1 PE=1 SV=3 3.89 2084.9 - 94908.9 - - - 1.6105 - 3.296 0.661 - 256.2 1 2 1 0.0037 20 0 0 0 1.39E+06 7.46E+05 - - - 8.802 0.9842 221125_WJC_METTL3_EV_vs_WT_F09.09734.09734.3 0.281 Jul-68 K.VK[136.11]LDSPAGTALSPSGHTK[136.11].L "sp|P32322|P5CR1_HUMAN,tr|E2QRB3|E2QRB3_HUMAN" 2 1780.9654 3.35 129751 9734 3 1780.967128 594.6624 "Pyrroline-5-carboxylate reductase 1, mitochondrial OS=Homo sapiens OX=9606 GN=PYCR1 PE=1 SV=2" 8.57 2085.3 - 142654 - - - 0.963 - 1.781 0.228 - 39.1 1 2 1 0.0017 18 0 0 0 2.77E+07 8.26E+06 - - - 2.5187 0.9525 221125_WJC_METTL3_EV_vs_WT_F09.09740.09740.3 0.0168 13/56 K.LITQTFSHHNQLAQK.T "sp|Q9Y266|NUDC_HUMAN,tr|A0A0A0MSS4|A0A0A0MSS4_HUMAN,tr|A0A0A0MSU9|A0A0A0MSU9_HUMAN" 3 1764.9271 2.95 129755 9740 3 1764.939891 589.3163 Nuclear migration protein nudC OS=Homo sapiens OX=9606 GN=NUDC PE=1 SV=1 8.76 2086.2 - 497797 - - - 7.2377 - 1.957 0.289 - 148.1 1 2 0 0.0128 15 0 0 0 2.75E+07 9.33E+06 - - - 3.5105 0.9974 221125_WJC_METTL3_EV_vs_WT_F09.09743.09743.3 0.124 Oct-56 K.LITQTFSHHNQLAQK[136.11].T "sp|Q9Y266|NUDC_HUMAN,tr|A0A0A0MSS4|A0A0A0MSS4_HUMAN,tr|A0A0A0MSU9|A0A0A0MSU9_HUMAN" 3 1772.9413 2.84 129758 9743 3 1772.942356 591.9877 Nuclear migration protein nudC OS=Homo sapiens OX=9606 GN=NUDC PE=1 SV=1 8.76 2086.5 - 170725 - - - 0.586 - 1.531 0.27 - 75.5 1 2 0 0.001 15 0 0 0 2.64E+07 9.28E+06 - - - 2.6613 0.9109 221125_WJC_METTL3_EV_vs_WT_F09.09753.09753.3 0.000581 Sep-56 F.SQPPAPPHQNTFPPR.S sp|Q96I24|FUBP3_HUMAN 1 1669.8325 -1 129766 9753 3 1669.838574 557.6181 Far upstream element-binding protein 3 OS=Homo sapiens OX=9606 GN=FUBP3 PE=1 SV=2 9.49 2087.9 - 151766 - - - 3.6447 - 1.943 0.407 - 69.9 1 1 0 0.0061 15 0 0 0 0.00E+00 0.00E+00 - - - 4.8092 1 221125_WJC_METTL3_EV_vs_WT_F09.09756.09756.2 1.15E-07 13/30 K.NEDVC[160.03]SC[160.03]STDTSEVPR.W sp|P49790|NU153_HUMAN 1 1854.736 1.4 129769 9756 2 1854.741796 928.3753 Nuclear pore complex protein Nup153 OS=Homo sapiens OX=9606 GN=NUP153 PE=1 SV=2 3.92 2088.3 - 50911.5 - - - 3.1212 - 3.053 0.797 - 604.6 1 2 0 0.0058 16 0 0 0 2.27E+06 1.62E+06 - - - 7.6699 0.9998 221125_WJC_METTL3_EV_vs_WT_F09.09758.09758.3 5.50E-06 Nov-52 K.K[136.11]GPGEVAGTVTGQK[136.11].R "sp|Q86U44|MTA70_HUMAN,tr|F5H6D8|F5H6D8_HUMAN,tr|H0YFV6|H0YFV6_HUMAN,tr|B4DTN4|B4DTN4_HUMAN" 4 1343.738 0 129770 9758 3 1343.741925 448.9199 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 8.59 2088.5 - 408565 - - - 2.9366 - 2.476 0.459 - 194.4 1 2 0 0.0039 14 0 0 0 1.39E+04 8.23E+06 - - - 6.0657 0.999 221125_WJC_METTL3_EV_vs_WT_F09.09761.09761.4 0.000883 16/102 K.VK[136.11]LDSPAGTALSPSGHTK[136.11].L "sp|P32322|P5CR1_HUMAN,tr|E2QRB3|E2QRB3_HUMAN" 2 1780.9654 2.65 129772 9761 4 1780.96984 446.2486 "Pyrroline-5-carboxylate reductase 1, mitochondrial OS=Homo sapiens OX=9606 GN=PYCR1 PE=1 SV=2" 8.57 2088.9 - 357023 - - - 2.4857 - 2.703 0.405 - 148.7 1 2 1 0.0044 18 0 0 0 3.27E+07 1.24E+07 - - - 3.0905 0.999 221125_WJC_METTL3_EV_vs_WT_F09.09764.09764.3 0.0623 Jun-60 R.DGQVINETSQHHDDLE.- sp|P08670|VIME_HUMAN 1 1835.7922 - 129775 9764 3 1835.795478 612.938 Vimentin OS=Homo sapiens OX=9606 GN=VIM PE=1 SV=4 4.28 2089.3 - 155404 - - - 1.7861 - 1.445 0.376 - 36.9 1 2 0 0.0033 16 0 0 0 - - - - - 3.6756 1 221125_WJC_METTL3_EV_vs_WT_F09.09766.09766.2 2.24E-09 30-Dec K.NEDVC[160.03]SC[160.03]STDTSEVPR[166.11].W sp|P49790|NU153_HUMAN 1 1864.7443 1.4 129777 9766 2 1864.743489 933.3794 Nuclear pore complex protein Nup153 OS=Homo sapiens OX=9606 GN=NUP153 PE=1 SV=2 3.92 2089.6 - 70474.7 - - - -0.4226 - 2.726 0.779 - 454.6 1 2 0 -0.0008 16 0 0 0 2.27E+06 1.62E+06 - - - 7.26 0.996 221125_WJC_METTL3_EV_vs_WT_F09.09771.09771.4 0.000704 15/90 K.DLVIERPRPDSRPAVK.K "sp|Q9Y520|PRC2C_HUMAN,tr|E7EPN9|E7EPN9_HUMAN" 2 1847.0377 0.97 129780 9771 4 1847.042421 462.7667 Protein PRRC2C OS=Homo sapiens OX=9606 GN=PRRC2C PE=1 SV=4 8.74 2090.3 - 348136 - - - 2.5397 - 2.158 0.267 - 148.5 1 2 0 0.0047 16 0 0 0 6.63E+06 6.81E+06 - - - 1.8196 0.973 221125_WJC_METTL3_EV_vs_WT_F09.09772.09772.4 0.0457 Sep-84 K.LITQTFSHHNQLAQK[136.11].T "sp|Q9Y266|NUDC_HUMAN,tr|A0A0A0MSS4|A0A0A0MSS4_HUMAN,tr|A0A0A0MSU9|A0A0A0MSU9_HUMAN" 3 1772.9413 2.65 129781 9772 4 1772.94552 444.2426 Nuclear migration protein nudC OS=Homo sapiens OX=9606 GN=NUDC PE=1 SV=1 8.76 2090.4 - 789830 - - - 2.3706 - 1.436 0.196 - 35.8 1 2 0 0.0042 15 0 0 0 2.80E+07 1.06E+07 - - - 1.0603 0.9878 221125_WJC_METTL3_EV_vs_WT_F09.09773.09773.3 2.47E-05 Dec-52 D.DAHPTLVTYADHSK[136.11].L "sp|Q86U44|MTA70_HUMAN,tr|F5H6D8|F5H6D8_HUMAN,tr|H0YFV6|H0YFV6_HUMAN,tr|B4DTN4|B4DTN4_HUMAN" 4 1561.7616 0.04 129782 9773 3 1561.766236 521.5945 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 5.98 2090.5 - 356263 - - - 2.955 - 2.371 0.503 - 253.9 1 1 0 0.0046 14 0 0 0 2.06E+05 4.70E+06 - - - 6.441 0.989 221125_WJC_METTL3_EV_vs_WT_F09.09775.09775.4 0.00257 Oct-84 R.KIDQEGKIPDETLEK.L "sp|Q9H845|ACAD9_HUMAN,tr|A0A7P0Z450|A0A7P0Z450_HUMAN,tr|D6RCD8|D6RCD8_HUMAN,tr|A0A7P0TB68|A0A7P0TB68_HUMAN,tr|A0A7P0T871|A0A7P0T871_HUMAN,tr|A0A7P0T7Z1|A0A7P0T7Z1_HUMAN,tr|A0A7P0T9N9|A0A7P0T9N9_HUMAN,tr|A0A7P0T8U3|A0A7P0T8U3_HUMAN,tr|A0A7P0TB58|A0A7P0TB58_HUMAN" 9 1741.9098 0.13 129784 9775 4 1741.913508 436.4847 "Complex I assembly factor ACAD9, mitochondrial OS=Homo sapiens OX=9606 GN=ACAD9 PE=1 SV=1" 4.51 2090.7 - 267531 - - - 2.1316 - 1.915 0.275 - 56.6 1 2 1 0.0037 15 0 0 0 3.23E+06 2.57E+07 - - - 1.851 0.9907 221125_WJC_METTL3_EV_vs_WT_F09.09784.09784.3 0.00851 Jul-60 K.TAC[160.03]HQAPEQVQVLSSK[136.11].S sp|Q8WUD6|CHPT1_HUMAN 1 1789.8872 0.66 129791 9784 3 1789.894028 597.6364 Cholinephosphotransferase 1 OS=Homo sapiens OX=9606 GN=CHPT1 PE=1 SV=1 6.41 2092 - 169537 - - - 3.7963 - 1.762 0.278 - 54.1 1 2 0 0.0068 16 0 0 0 3.04E+06 4.61E+06 - - - 3.091 0.9998 221125_WJC_METTL3_EV_vs_WT_F09.09787.09787.2 0.000894 30-Jul R.DGQVINETSQHHDDLE.- sp|P08670|VIME_HUMAN 1 1835.7922 - 129794 9787 2 1835.795148 918.9034 Vimentin OS=Homo sapiens OX=9606 GN=VIM PE=1 SV=4 4.28 2092.4 - 70291.7 - - - 1.6064 - 2.024 0.59 - 103.1 1 2 0 0.0029 16 0 0 0 - - - - - 5.1313 1 221125_WJC_METTL3_EV_vs_WT_F09.09801.09801.3 1.58E-05 16/60 R.EQTEGEYSSLEHESAR[166.11].G "sp|O43837|IDH3B_HUMAN,tr|A0A087WZN1|A0A087WZN1_HUMAN,tr|A0A087X2E5|A0A087X2E5_HUMAN" 3 1860.8001 1.8 129804 9801 3 1860.80002 621.274 "Isocitrate dehydrogenase [NAD] subunit beta, mitochondrial OS=Homo sapiens OX=9606 GN=IDH3B PE=1 SV=2" 4.32 2094.3 - 154816 - - - -0.0618 - 3.064 0.633 - 409.3 1 2 0 -0.0001 16 0 0 0 1.35E+07 7.54E+06 - - - 8.4703 0.9994 221125_WJC_METTL3_EV_vs_WT_F09.09802.09802.3 0.000313 Sep-68 K.EGHPVTSEPSRPEPAVFK.A sp|Q16762|THTR_HUMAN 1 1962.9799 2.84 129805 9802 3 1962.986107 655.3339 Thiosulfate sulfurtransferase OS=Homo sapiens OX=9606 GN=TST PE=1 SV=4 5.5 2094.4 - 139846 - - - 3.1417 - 1.777 0.445 - 78.1 1 2 0 0.0062 18 0 0 0 2.12E+07 7.47E+06 - - - 4.9312 0.9988 221125_WJC_METTL3_EV_vs_WT_F09.09805.09805.3 0.0021 Jul-64 K.K[136.11]DTETENPPVENTLSPK[136.11].L sp|Q96RS0|TGS1_HUMAN 1 1913.9553 2.28 129808 9805 3 1913.957771 638.9924 Trimethylguanosine synthase OS=Homo sapiens OX=9606 GN=TGS1 PE=1 SV=3 4.41 2094.8 - 68663.5 - - - 1.29 - 1.688 0.314 - 53.8 1 2 0 0.0025 17 0 0 0 3.85E+06 1.69E+06 - - - 3.3627 0.911 221125_WJC_METTL3_EV_vs_WT_F09.09810.09810.4 0.163 11/102 K.EGHPVTSEPSR[166.11]PEPAVFK[136.11].A sp|Q16762|THTR_HUMAN 1 1981.0024 2.88 129811 9810 4 1981.003083 496.2579 Thiosulfate sulfurtransferase OS=Homo sapiens OX=9606 GN=TST PE=1 SV=4 5.5 2095.6 - 496883 - - - 0.3397 - 1.789 0.115 - 75.1 1 2 0 0.0007 18 0 0 0 4.58E+07 1.59E+07 - - - 0.426 1 221125_WJC_METTL3_EV_vs_WT_F09.09811.09811.3 0.00424 13/48 K.QEYDESGPSIVHR.K "sp|Q6S8J3|POTEE_HUMAN,sp|P63261|ACTG_HUMAN,sp|Q9BYX7|ACTBM_HUMAN,sp|P60709|ACTB_HUMAN,sp|A5A3E0|POTEF_HUMAN,sp|P0CG38|POTEI_HUMAN,sp|P0CG39|POTEJ_HUMAN,tr|A0A2R8YFE2|A0A2R8YFE2_HUMAN,tr|A0A804GS07|A0A804GS07_HUMAN,tr|A0A6Q8PFE4|A0A6Q8PFE4_HUMAN,tr|I3L4N8|I3L4N8_HUMAN" 11 1515.6954 1.02 129812 9811 3 1515.697985 506.2391 POTE ankyrin domain family member E OS=Homo sapiens OX=9606 GN=POTEE PE=2 SV=3 4.65 2095.7 - 367968 - - - 1.7147 - 2.501 0.546 - 268.5 1 2 0 0.0026 13 0 0 0 1.14E+07 1.11E+07 - - - 7.1121 0.8648 221125_WJC_METTL3_EV_vs_WT_F09.09826.09826.3 0.0864 Jun-48 R.LYKEELEQTYHAK.L "sp|P20700|LMNB1_HUMAN,tr|E9PBF6|E9PBF6_HUMAN,tr|A0A0D9SFE5|A0A0D9SFE5_HUMAN" 3 1650.8253 1.5 129823 9826 3 1650.82671 551.2824 Lamin-B1 OS=Homo sapiens OX=9606 GN=LMNB1 PE=1 SV=2 5.5 2097.7 - 186233 - - - 0.8317 - 1.244 0.178 - 38 1 2 1 0.0014 13 0 0 0 3.16E+06 2.10E+06 - - - 1.1161 0.9992 221125_WJC_METTL3_EV_vs_WT_F09.09828.09828.4 0.00214 11/120 K.LEPGGFGEKPVRPGGGDTSPR.Y "sp|Q5JSZ5|PRC2B_HUMAN,tr|A0A804HKC3|A0A804HKC3_HUMAN,tr|A0A804HJR4|A0A804HJR4_HUMAN" 3 2109.0603 1.3 129824 9828 4 2109.061423 528.2724 Protein PRRC2B OS=Homo sapiens OX=9606 GN=PRRC2B PE=1 SV=2 6.18 2097.9 - 259574 - - - 0.5249 - 2.02 0.308 - 74.6 1 2 0 0.0011 21 0 0 0 2.42E+06 1.87E+06 - - - 2.139 0.9999 221125_WJC_METTL3_EV_vs_WT_F09.09836.09836.3 0.000165 14/44 K.KPHIYYGSLEEK.E sp|O43172|PRP4_HUMAN 1 1462.7456 1.02 129830 9836 3 1462.747067 488.5892 U4\U6 small nuclear ribonucleoprotein Prp4 OS=Homo sapiens OX=9606 GN=PRPF4 PE=1 SV=2 6.75 2098.9 - 658655 - - - 0.9824 - 2.301 0.381 - 235.5 1 2 0 0.0014 12 0 0 0 1.48E+07 1.45E+07 - - - 5.0973 0.9469 221125_WJC_METTL3_EV_vs_WT_F09.09841.09841.2 1.16E-05 24-Aug Q.VINETSQHHDDLE.- sp|P08670|VIME_HUMAN 1 1535.6852 - 129835 9841 2 1535.6906 768.8499 Vimentin OS=Homo sapiens OX=9606 GN=VIM PE=1 SV=4 4.52 2099.5 - 113168 - - - 3.5066 - 1.654 0.578 - 124.6 1 1 0 0.0054 13 0 0 0 - - - - - 4.5999 1 221125_WJC_METTL3_EV_vs_WT_F09.09845.09845.3 3.09E-07 Nov-60 R.NTVSQSISGDPEIDK[136.11]K[136.11].L "sp|Q9BY44|EIF2A_HUMAN,tr|F8WAE5|F8WAE5_HUMAN" 2 1732.8814 0.4 129837 9845 3 1732.882291 578.6344 Eukaryotic translation initiation factor 2A OS=Homo sapiens OX=9606 GN=EIF2A PE=1 SV=3 4.56 2100.1 - 259123 - - - 0.5096 - 2.29 0.539 - 150.5 1 2 0 0.0009 16 0 0 0 1.24E+06 3.11E+06 - - - 6.675 0.9999 221125_WJC_METTL3_EV_vs_WT_F09.09846.09846.4 6.57E-09 18/102 K.QLGDSPAEDK[136.11]SSFK[136.11]PYSK[136.11].G sp|Q9H7S9|ZN703_HUMAN 1 2007.0011 0.67 129838 9846 4 2006.999606 502.7576 Zinc finger protein 703 OS=Homo sapiens OX=9606 GN=ZNF703 PE=1 SV=1 6.12 2100.2 - 508617 - - - -0.7623 - 3.228 0.534 - 247.3 1 2 1 -0.0015 18 0 0 0 4.25E+06 6.31E+06 - - - 4.2749 0.9999 221125_WJC_METTL3_EV_vs_WT_F09.09851.09851.3 1.66E-05 Oct-68 K.EGHPVTSEPSR[166.11]PEPAVFK[136.11].A sp|Q16762|THTR_HUMAN 1 1981.0024 2.57 129841 9851 3 1981.000595 661.3414 Thiosulfate sulfurtransferase OS=Homo sapiens OX=9606 GN=TST PE=1 SV=4 5.5 2100.9 - 410337 - - - -0.9162 - 1.949 0.434 - 75.1 1 2 0 -0.0018 18 0 0 0 1.92E+07 7.47E+06 - - - 5.0399 1 221125_WJC_METTL3_EV_vs_WT_F09.09858.09858.3 1.24E-10 21/76 R.SAAPSTLDSSSTAPAQLGKK.G "sp|Q9Y5M8|SRPRB_HUMAN,tr|H7C4H2|H7C4H2_HUMAN" 2 1915.9851 1.2 129846 9858 3 1915.987168 639.669 Signal recognition particle receptor subunit beta OS=Homo sapiens OX=9606 GN=SRPRB PE=1 SV=3 8.31 2101.8 - 555529 - - - 1.0872 - 4.043 0.725 - 425.4 1 2 0 0.0021 20 0 0 0 1.05E+07 8.79E+06 - - - 10.0116 0.9942 221125_WJC_METTL3_EV_vs_WT_F09.09861.09861.4 0.00587 13/84 K.DTGKTPVEPEVAIHR.L "sp|P60866|RS20_HUMAN,tr|E5RJX2|E5RJX2_HUMAN,tr|E5RIP1|E5RIP1_HUMAN" 3 1647.858 1.35 129849 9861 4 1647.860983 412.9718 40S ribosomal protein S20 OS=Homo sapiens OX=9606 GN=RPS20 PE=1 SV=1 5.45 2102.1 - 313696 - - - 1.7896 - 2.273 0.288 - 86.2 1 2 1 0.0029 15 0 0 0 1.55E+09 1.15E+09 - - - 2.0257 0.9999 221125_WJC_METTL3_EV_vs_WT_F09.09862.09862.3 2.30E-06 Oct-52 K.VETPHVTIEDAQHR.K "sp|Q5T200|ZC3HD_HUMAN,tr|A0A7I2V4I5|A0A7I2V4I5_HUMAN" 2 1630.8063 0.19 129850 9862 3 1630.810704 544.6094 Zinc finger CCCH domain-containing protein 13 OS=Homo sapiens OX=9606 GN=ZC3H13 PE=1 SV=1 5.27 2102.2 - 187889 - - - 2.6803 - 2.204 0.507 - 93.6 1 2 0 0.0044 14 0 0 0 8.63E+06 4.61E+07 - - - 6.2915 0.9976 221125_WJC_METTL3_EV_vs_WT_F09.09868.09868.3 0.000691 Sep-84 R.VKDMAAPGTSSVPAPTAGNAEK.L "sp|Q7L014|DDX46_HUMAN,tr|A0A0C4DG89|A0A0C4DG89_HUMAN" 2 2098.0365 3.82 129854 9868 3 2098.040543 700.3528 Probable ATP-dependent RNA helicase DDX46 OS=Homo sapiens OX=9606 GN=DDX46 PE=1 SV=2 6.04 2103.1 - 189214 - - - 1.9418 - 1.764 0.396 - 63.1 1 2 1 0.0041 22 0 0 0 4.49E+06 1.17E+06 - - - 4.2995 0.9991 221125_WJC_METTL3_EV_vs_WT_F09.09876.09876.3 0.000159 Sep-32 R.MDYEDDRLR.D "sp|P43243|MATR3_HUMAN,tr|A8MXP9|A8MXP9_HUMAN,tr|D6R991|D6R991_HUMAN,tr|A0A0R4J2E8|A0A0R4J2E8_HUMAN,tr|D6REM6|D6REM6_HUMAN" 5 1211.5241 1.47 129860 9876 3 1211.524984 404.8486 Matrin-3 OS=Homo sapiens OX=9606 GN=MATR3 PE=1 SV=2 4.23 2104.1 - 261518 - - - 0.7412 - 1.68 0.4 - 232.1 1 2 1 0.0009 9 0 0 0 3.31E+06 2.25E+06 - - - 4.5629 0.9373 221125_WJC_METTL3_EV_vs_WT_F09.09877.09877.4 0.13 Aug-66 K.QK[136.11]EVC[160.03]INPYHYK[136.11].R "sp|Q99717|SMAD5_HUMAN,sp|Q15797|SMAD1_HUMAN,tr|D6RBB4|D6RBB4_HUMAN,tr|D6RD62|D6RD62_HUMAN" 4 1593.7944 1.07 129861 9877 4 1593.795903 399.4559 Mothers against decapentaplegic homolog 5 OS=Homo sapiens OX=9606 GN=SMAD5 PE=1 SV=1 8.16 2104.3 - 212139 - - - 0.9129 - 1.515 0.185 - 52.9 1 2 1 0.0015 12 0 0 0 7.21E+06 6.72E+06 - - - 0.993 0.9983 221125_WJC_METTL3_EV_vs_WT_F09.09879.09879.3 4.69 Jul-48 K.EFHLNESGDPSSK.S "sp|Q01105|SET_HUMAN,sp|P0DME0|SETLP_HUMAN,tr|A0A0C4DFV9|A0A0C4DFV9_HUMAN" 3 1445.6423 0.68 129863 9879 3 1445.64473 482.888 Protein SET OS=Homo sapiens OX=9606 GN=SET PE=1 SV=3 4.65 2104.5 - 129046 - - - 1.6899 - 1.61 0.308 - 53.8 1 2 0 0.0024 13 0 0 0 2.48E+06 3.65E+06 - - - 3.2644 0.9947 221125_WJC_METTL3_EV_vs_WT_F09.09888.09888.3 0.00629 Oct-44 K.QKEVC[160.03]INPYHYK.R "sp|Q99717|SMAD5_HUMAN,sp|Q15797|SMAD1_HUMAN,tr|D6RBB4|D6RBB4_HUMAN,tr|D6RD62|D6RD62_HUMAN" 4 1577.766 0.96 129870 9888 3 1577.77034 526.9293 Mothers against decapentaplegic homolog 5 OS=Homo sapiens OX=9606 GN=SMAD5 PE=1 SV=1 8.16 2105.6 - 250608 - - - 2.7203 - 1.927 0.332 - 152.9 1 2 1 0.0043 12 0 0 0 6.38E+06 6.63E+06 - - - 4.0585 0.9999 221125_WJC_METTL3_EV_vs_WT_F09.09895.09895.3 4.87E-08 24/48 R.HRLDLGEDYPSGK.K sp|O43143|DHX15_HUMAN 1 1485.7212 1.14 129875 9895 3 1485.718866 496.2477 Pre-mRNA-splicing factor ATP-dependent RNA helicase DHX15 OS=Homo sapiens OX=9606 GN=DHX15 PE=1 SV=2 5.38 2106.6 - 2.20E+06 - - - -1.575 - 3.504 0.456 - 1056.3 1 2 1 -0.0023 13 0 0 0 9.13E+07 8.00E+07 - - - 7.023 0.9999 221125_WJC_METTL3_EV_vs_WT_F09.09900.09900.3 4.40E-06 Dec-64 K.EEETSIDVAGKPNEVTK.A sp|P53985|MOT1_HUMAN 1 1844.9004 4.14 129878 9900 3 1844.902211 615.9741 Monocarboxylate transporter 1 OS=Homo sapiens OX=9606 GN=SLC16A1 PE=1 SV=3 4.25 2107.3 - 211712 - - - 1.0071 - 2.191 0.423 - 140.7 1 2 0 0.0019 17 0 0 0 3.34E+06 8.07E+05 - - - 5.237 0.9925 221125_WJC_METTL3_EV_vs_WT_F09.09908.09908.3 9.10E-06 23/48 T.GKTPVEPEVAIHR.L "sp|P60866|RS20_HUMAN,tr|E5RJX2|E5RJX2_HUMAN,tr|E5RIP1|E5RIP1_HUMAN,tr|A0A7P0S5H5|A0A7P0S5H5_HUMAN" 4 1431.7834 1.46 129884 9908 3 1431.78572 478.2684 40S ribosomal protein S20 OS=Homo sapiens OX=9606 GN=RPS20 PE=1 SV=1 6.76 2108.3 - 591147 - - - 1.6113 - 3.479 0.568 - 992.6 1 1 1 0.0023 13 0 0 0 6.12E+07 4.20E+07 - - - 8.2523 0.9569 221125_WJC_METTL3_EV_vs_WT_F09.09910.09910.2 0.065 16-Aug K.YKDDPVDLR.L "sp|Q9Y2W1|TR150_HUMAN,tr|A0A3B3ITZ9|A0A3B3ITZ9_HUMAN" 2 1119.556 3.04 129886 9910 2 1119.559249 560.7853 Thyroid hormone receptor-associated protein 3 OS=Homo sapiens OX=9606 GN=THRAP3 PE=1 SV=2 4.43 2108.6 - 280412 - - - 2.8681 - 1.554 0.283 - 183.6 1 2 1 0.0032 9 0 0 0 7.82E+06 2.57E+06 - - - 2.4056 0.9923 221125_WJC_METTL3_EV_vs_WT_F09.09913.09913.2 0.000239 28-Sep K.DTGKTPVEPEVAIHR.L "sp|P60866|RS20_HUMAN,tr|E5RJX2|E5RJX2_HUMAN,tr|E5RIP1|E5RIP1_HUMAN" 3 1647.858 1.63 129889 9913 2 1647.860731 824.9363 40S ribosomal protein S20 OS=Homo sapiens OX=9606 GN=RPS20 PE=1 SV=1 5.45 2109 - 143667 - - - 1.6367 - 1.645 0.416 - 178.6 1 2 1 0.0027 15 0 0 0 1.80E+07 1.11E+07 - - - 3.3364 0.9336 221125_WJC_METTL3_EV_vs_WT_F09.09918.09918.2 0.0219 14-Aug V.EPEVAIHR.L "sp|P60866|RS20_HUMAN,tr|E5RJX2|E5RJX2_HUMAN,tr|E5RIP1|E5RIP1_HUMAN,tr|A0A7P0S5H5|A0A7P0S5H5_HUMAN" 4 949.4981 1.38 129892 9918 2 949.496564 475.7563 40S ribosomal protein S20 OS=Homo sapiens OX=9606 GN=RPS20 PE=1 SV=1 5.4 2109.6 - 579605 - - - -1.6493 - 1.607 0.302 - 392.7 1 1 0 -0.0016 8 0 0 0 2.62E+07 1.89E+07 - - - 2.7018 1 221125_WJC_METTL3_EV_vs_WT_F09.09922.09922.2 4.22E-14 20/42 R.SSGSPYGGGYGSGGGSGGYGSR.R "sp|P51991|ROA3_HUMAN,tr|A0A7I2V5D8|A0A7I2V5D8_HUMAN,tr|A0A7I2V2R3|A0A7I2V2R3_HUMAN,tr|A0A7I2V4G0|A0A7I2V4G0_HUMAN,tr|A0A7I2V402|A0A7I2V402_HUMAN,tr|H7C1J8|H7C1J8_HUMAN" 6 1909.7827 1.52 129896 9922 2 1909.782158 955.8986 Heterogeneous nuclear ribonucleoprotein A3 OS=Homo sapiens OX=9606 GN=HNRNPA3 PE=1 SV=2 8.22 2110.1 - 266044 - - - -0.2822 - 4.005 0.774 - 1019 1 2 0 -0.0005 22 0 0 0 1.05E+08 6.89E+07 - - - 8.1689 1 221125_WJC_METTL3_EV_vs_WT_F09.09923.09923.2 3.74E-13 16/42 R.SSGSPYGGGYGSGGGSGGYGSR[166.11].R "sp|P51991|ROA3_HUMAN,tr|A0A7I2V5D8|A0A7I2V5D8_HUMAN,tr|A0A7I2V2R3|A0A7I2V2R3_HUMAN,tr|A0A7I2V4G0|A0A7I2V4G0_HUMAN,tr|A0A7I2V402|A0A7I2V402_HUMAN,tr|H7C1J8|H7C1J8_HUMAN" 6 1919.791 1.52 129897 9923 2 1919.788853 960.9028 Heterogeneous nuclear ribonucleoprotein A3 OS=Homo sapiens OX=9606 GN=HNRNPA3 PE=1 SV=2 8.22 2110.2 - 264720 - - - -1.1012 - 3.306 0.756 - 489 1 2 0 -0.0021 22 0 0 0 1.05E+08 6.89E+07 - - - 7.5639 0.9887 221125_WJC_METTL3_EV_vs_WT_F09.09927.09927.3 8.82E-09 20/48 T.GK[136.11]TPVEPEVAIHR[166.11].L "sp|P60866|RS20_HUMAN,tr|E5RJX2|E5RJX2_HUMAN,tr|E5RIP1|E5RIP1_HUMAN,tr|A0A7P0S5H5|A0A7P0S5H5_HUMAN" 4 1449.8059 1.46 129899 9927 3 1449.804856 484.2759 40S ribosomal protein S20 OS=Homo sapiens OX=9606 GN=RPS20 PE=1 SV=1 6.76 2110.7 - 1.55E+06 - - - -0.7084 - 3.361 0.448 - 748.9 1 1 1 -0.001 13 0 0 0 6.12E+07 4.20E+07 - - - 6.8212 0.9612 221125_WJC_METTL3_EV_vs_WT_F09.09928.09928.2 0.0594 14-Aug V.EPEVAIHR[166.11].L "sp|P60866|RS20_HUMAN,tr|E5RJX2|E5RJX2_HUMAN,tr|E5RIP1|E5RIP1_HUMAN,tr|A0A7P0S5H5|A0A7P0S5H5_HUMAN" 4 959.5064 1.38 129900 9928 2 959.506126 480.7605 40S ribosomal protein S20 OS=Homo sapiens OX=9606 GN=RPS20 PE=1 SV=1 5.4 2110.9 - 667028 - - - -0.2856 - 1.768 0.267 - 389.9 1 1 0 -0.0003 8 0 0 0 2.62E+07 1.89E+07 - - - 2.7316 0.9998 221125_WJC_METTL3_EV_vs_WT_F09.09929.09929.3 0.0115 14/56 K.DTGKTPVEPEVAIHR[166.11].L "sp|P60866|RS20_HUMAN,tr|E5RJX2|E5RJX2_HUMAN,tr|E5RIP1|E5RIP1_HUMAN" 3 1657.8663 - 129901 9929 3 1657.86622 553.6294 40S ribosomal protein S20 OS=Homo sapiens OX=9606 GN=RPS20 PE=1 SV=1 5.45 2111 - 421511 - - - -0.0507 - 2.781 0.426 - 357.2 1 2 1 -0.0001 15 0 0 0 - - - - - 5.9583 0.9897 221125_WJC_METTL3_EV_vs_WT_F09.09930.09930.2 3.61E-07 Oct-32 R.SDSPVPTAPTSGGPK[136.11]PS.T "sp|Q86U44|MTA70_HUMAN,tr|B4E349|B4E349_HUMAN,tr|F5H6D8|F5H6D8_HUMAN,tr|B4DTN4|B4DTN4_HUMAN" 4 1588.7824 0 129902 9930 2 1588.780121 795.3985 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 5.55 2111.1 - 233925 - - - -1.4445 - 1.898 0.585 - 194.5 1 1 0 -0.0023 17 0 0 0 2.52E+05 1.55E+08 - - - 4.9365 0.9962 221125_WJC_METTL3_EV_vs_WT_F09.09939.09939.2 0.000222 13/28 K.DTGK[136.11]TPVEPEVAIHR[166.11].L "sp|P60866|RS20_HUMAN,tr|E5RJX2|E5RJX2_HUMAN,tr|E5RIP1|E5RIP1_HUMAN" 3 1665.8805 1.63 129909 9939 2 1665.876934 833.9475 40S ribosomal protein S20 OS=Homo sapiens OX=9606 GN=RPS20 PE=1 SV=1 5.45 2112.2 - 555129 - - - -2.143 - 2.055 0.508 - 345.2 1 2 1 -0.0036 15 0 0 0 1.80E+07 1.11E+07 - - - 4.5628 1 221125_WJC_METTL3_EV_vs_WT_F09.09940.09940.3 9.21E-08 18/84 R.SSGSPYGGGYGSGGGSGGYGSR.R "sp|P51991|ROA3_HUMAN,tr|A0A7I2V5D8|A0A7I2V5D8_HUMAN,tr|A0A7I2V2R3|A0A7I2V2R3_HUMAN,tr|A0A7I2V4G0|A0A7I2V4G0_HUMAN,tr|A0A7I2V402|A0A7I2V402_HUMAN,tr|H7C1J8|H7C1J8_HUMAN" 6 1909.7827 1.67 129910 9940 3 1909.780528 637.6015 Heterogeneous nuclear ribonucleoprotein A3 OS=Homo sapiens OX=9606 GN=HNRNPA3 PE=1 SV=2 8.22 2112.3 - 445004 - - - -1.1357 - 3.142 0.666 - 384.9 1 2 0 -0.0022 22 0 0 0 3.08E+07 1.84E+07 - - - 8.6789 1 221125_WJC_METTL3_EV_vs_WT_F09.09952.09952.3 3.54E-10 18/84 R.SSGSPYGGGYGSGGGSGGYGSR[166.11].R "sp|P51991|ROA3_HUMAN,tr|A0A7I2V5D8|A0A7I2V5D8_HUMAN,tr|A0A7I2V2R3|A0A7I2V2R3_HUMAN,tr|A0A7I2V4G0|A0A7I2V4G0_HUMAN,tr|A0A7I2V402|A0A7I2V402_HUMAN,tr|H7C1J8|H7C1J8_HUMAN" 6 1919.791 1.67 129920 9952 3 1919.781766 640.9376 Heterogeneous nuclear ribonucleoprotein A3 OS=Homo sapiens OX=9606 GN=HNRNPA3 PE=1 SV=2 8.22 2113.5 - 707878 - - - -4.7927 - 3.52 0.706 - 310 1 2 0 -0.0092 22 0 0 0 3.08E+07 1.84E+07 - - - 9.3923 1 221125_WJC_METTL3_EV_vs_WT_F09.09968.09968.3 9.73E-05 13/60 R.ASPSPQPSSQPLQIHR[166.11].Q "sp|Q9HC35|EMAL4_HUMAN,tr|B5MBZ0|B5MBZ0_HUMAN" 2 1738.899 4.61 129932 9968 3 1738.898376 580.6403 Echinoderm microtubule-associated protein-like 4 OS=Homo sapiens OX=9606 GN=EML4 PE=1 SV=3 9.8 2115.5 - 462412 - - - -0.3594 - 2.831 0.438 - 245.6 1 2 0 -0.0006 16 0 0 0 9.25E+07 2.01E+07 - - - 6.0932 1 221125_WJC_METTL3_EV_vs_WT_F09.09973.09973.3 2.60E-09 19/48 R.HR[166.11]LDLGEDYPSGK[136.11].K sp|O43143|DHX15_HUMAN 1 1503.7437 1.13 129935 9973 3 1503.737989 502.2552 Pre-mRNA-splicing factor ATP-dependent RNA helicase DHX15 OS=Homo sapiens OX=9606 GN=DHX15 PE=1 SV=2 5.38 2116.1 - 1.71E+06 - - - -3.7819 - 3.436 0.601 - 512.8 1 2 1 -0.0057 13 0 0 0 9.03E+07 8.00E+07 - - - 8.5855 0.9995 221125_WJC_METTL3_EV_vs_WT_F09.09991.09991.4 0.00222 15/84 K.DTGK[136.11]TPVEPEVAIHR[166.11].L "sp|P60866|RS20_HUMAN,tr|E5RJX2|E5RJX2_HUMAN,tr|E5RIP1|E5RIP1_HUMAN" 3 1665.8805 1.35 129950 9991 4 1665.87551 417.4774 40S ribosomal protein S20 OS=Homo sapiens OX=9606 GN=RPS20 PE=1 SV=1 5.45 2118.1 - 2.73E+07 - - - -2.9978 - 2.953 0.474 - 238.8 1 2 1 -0.005 15 0 0 0 1.55E+09 1.15E+09 - - - 3.7378 0.9994 221125_WJC_METTL3_EV_vs_WT_F09.09996.09996.3 0.00144 Nov-44 R.SRAEAESWYQTK.Y "sp|P48668|K2C6C_HUMAN,sp|P04259|K2C6B_HUMAN,sp|O95678|K2C75_HUMAN,sp|P02538|K2C6A_HUMAN" 4 1454.679 9.06 129954 9996 3 1454.67736 485.9003 "Keratin, type II cytoskeletal 6C OS=Homo sapiens OX=9606 GN=KRT6C PE=1 SV=3" 5.86 2118.7 - 1.05E+06 - - - -1.1322 - 2.224 0.385 - 182.2 1 2 1 -0.0016 12 0 0 0 3.60E+07 3.98E+06 - - - 5.0475 0.9927 221125_WJC_METTL3_EV_vs_WT_F09.10008.10008.3 0.0111 Nov-60 K.STAGDTHLGGEDFDNR[166.11].M "sp|P54652|HSP72_HUMAN,sp|P11142|HSP7C_HUMAN,tr|E9PKE3|E9PKE3_HUMAN,tr|E9PN89|E9PN89_HUMAN" 4 1700.7266 0.18 129961 10008 3 1700.711878 567.9161 Heat shock-related 70 kDa protein 2 OS=Homo sapiens OX=9606 GN=HSPA2 PE=1 SV=1 4.22 2120.2 - 1.45E+06 - - - -8.6422 - 2.105 0.478 - 110.6 1 2 0 -0.0147 16 0 0 0 7.54E+06 4.13E+07 - - - 5.775 0.9991 221125_WJC_METTL3_EV_vs_WT_F09.10025.10025.4 0.00272 15/78 K.EGLELPEDEEEK[136.11]K[136.11]K[136.11].Q "sp|Q58FG0|HS905_HUMAN,sp|P08238|HS90B_HUMAN,sp|Q58FF7|H90B3_HUMAN,sp|P07900|HS90A_HUMAN" 4 1695.8629 0.83 129972 10025 4 1695.858256 424.973 Putative heat shock protein HSP 90-alpha A5 OS=Homo sapiens OX=9606 GN=HSP90AA5P PE=2 SV=1 4.31 2122.2 - 2.30E+06 - - - -2.7449 - 2.932 0.418 - 216 1 2 1 -0.0047 14 0 0 0 1.98E+08 2.37E+08 - - - 3.2545 0.9969 221125_WJC_METTL3_EV_vs_WT_F09.10029.10029.3 0.00195 15/52 K.EGLELPEDEEEKKK.Q "sp|Q58FG0|HS905_HUMAN,sp|P08238|HS90B_HUMAN,sp|Q58FF7|H90B3_HUMAN,sp|P07900|HS90A_HUMAN" 4 1671.8203 1.21 129974 10029 3 1671.812346 558.2807 Putative heat shock protein HSP 90-alpha A5 OS=Homo sapiens OX=9606 GN=HSP90AA5P PE=2 SV=1 4.31 2122.7 - 2.37E+06 - - - -4.7643 - 2.639 0.429 - 240.9 1 2 1 -0.008 14 0 0 0 2.21E+08 1.83E+08 - - - 5.8996 0.9999 221125_WJC_METTL3_EV_vs_WT_F09.10034.10034.3 1.87E-05 18/56 K.DTGKTPVEPEVAIHR.L "sp|P60866|RS20_HUMAN,tr|E5RJX2|E5RJX2_HUMAN,tr|E5RIP1|E5RIP1_HUMAN" 3 1647.858 1.37 129976 10034 3 1647.854706 550.2933 40S ribosomal protein S20 OS=Homo sapiens OX=9606 GN=RPS20 PE=1 SV=1 5.45 2123.3 - 1.97E+06 - - - -2.0196 - 3.478 0.546 - 563.6 1 2 1 -0.0033 15 0 0 0 1.15E+09 8.37E+08 - - - 7.8789 0.999 221125_WJC_METTL3_EV_vs_WT_F09.10036.10036.4 1.61E-07 16/78 K.EGLELPEDEEEKKK.Q "sp|Q58FG0|HS905_HUMAN,sp|P08238|HS90B_HUMAN,sp|Q58FF7|H90B3_HUMAN,sp|P07900|HS90A_HUMAN" 4 1671.8203 0.83 129978 10036 4 1671.816319 418.9624 Putative heat shock protein HSP 90-alpha A5 OS=Homo sapiens OX=9606 GN=HSP90AA5P PE=2 SV=1 4.31 2123.5 - 2.52E+06 - - - -2.3878 - 2.914 0.391 - 252.5 1 2 1 -0.004 14 0 0 0 1.98E+08 2.38E+08 - - - 3.0174 0.9993 221125_WJC_METTL3_EV_vs_WT_F09.10037.10037.3 0.000285 15/52 K.EGLELPEDEEEK[136.11]K[136.11]K[136.11].Q "sp|Q58FG0|HS905_HUMAN,sp|P08238|HS90B_HUMAN,sp|Q58FF7|H90B3_HUMAN,sp|P07900|HS90A_HUMAN" 4 1695.8629 1.19 129979 10037 3 1695.860483 566.2949 Putative heat shock protein HSP 90-alpha A5 OS=Homo sapiens OX=9606 GN=HSP90AA5P PE=2 SV=1 4.31 2123.5 - 2.46E+06 - - - -1.4317 - 2.479 0.362 - 201.4 1 2 1 -0.0024 14 0 0 0 2.18E+08 1.83E+08 - - - 4.9879 1 221125_WJC_METTL3_EV_vs_WT_F09.10040.10040.3 7.57E-11 22/60 K.R[166.11]PELLTHSTTEVTQPR[166.11].T "sp|P78347|GTF2I_HUMAN,tr|A0A494C0Q7|A0A494C0Q7_HUMAN,tr|A0A494C1K3|A0A494C1K3_HUMAN" 3 1883.9968 1.5 129980 10040 3 1883.998807 629.0062 General transcription factor II-I OS=Homo sapiens OX=9606 GN=GTF2I PE=1 SV=2 6.76 2123.9 - 906279 - - - 1.0573 - 4.238 0.557 - 930.8 1 2 0 0.002 16 0 0 0 2.06E+09 1.38E+09 - - - 8.4548 1 221125_WJC_METTL3_EV_vs_WT_F09.10044.10044.3 4.67E-11 23/60 K.RPELLTHSTTEVTQPR.T "sp|P78347|GTF2I_HUMAN,tr|A0A494C0Q7|A0A494C0Q7_HUMAN,tr|A0A494C1K3|A0A494C1K3_HUMAN" 3 1863.9803 1.5 129982 10044 3 1863.976187 622.334 General transcription factor II-I OS=Homo sapiens OX=9606 GN=GTF2I PE=1 SV=2 6.76 2124.4 - 1.07E+06 - - - -2.1932 - 4.239 0.554 - 1106.6 1 2 0 -0.0041 16 0 0 0 2.06E+09 1.38E+09 - - - 8.4214 1 221125_WJC_METTL3_EV_vs_WT_F09.10046.10046.4 5.50E-08 20/90 K.R[166.11]PELLTHSTTEVTQPR[166.11].T "sp|P78347|GTF2I_HUMAN,tr|A0A494C0Q7|A0A494C0Q7_HUMAN,tr|A0A494C1K3|A0A494C1K3_HUMAN" 3 1883.9968 1.46 129983 10046 4 1883.994455 472.0065 General transcription factor II-I OS=Homo sapiens OX=9606 GN=GTF2I PE=1 SV=2 6.76 2124.6 - 950755 - - - -1.2527 - 3.241 0.476 - 377.6 1 2 0 -0.0024 16 0 0 0 1.07E+09 7.34E+08 - - - 3.7827 0.9999 221125_WJC_METTL3_EV_vs_WT_F09.10056.10056.4 1.55E-09 27/90 K.RPELLTHSTTEVTQPR.T "sp|P78347|GTF2I_HUMAN,tr|A0A494C0Q7|A0A494C0Q7_HUMAN,tr|A0A494C1K3|A0A494C1K3_HUMAN" 3 1863.9803 1.46 129990 10056 4 1863.973622 467.0023 General transcription factor II-I OS=Homo sapiens OX=9606 GN=GTF2I PE=1 SV=2 6.76 2125.8 - 1.74E+06 - - - -3.5692 - 4.01 0.537 - 677.9 1 2 0 -0.0067 16 0 0 0 1.07E+09 7.34E+08 - - - 4.3874 0.8357 221125_WJC_METTL3_EV_vs_WT_F09.10078.10078.4 0.00567 Sep-66 K.VC[160.03]EIHFHEINNK.M "sp|O43347|MSI1H_HUMAN,sp|Q96DH6|MSI2H_HUMAN,tr|B4DHE8|B4DHE8_HUMAN,tr|A0A6Q8PGD8|A0A6Q8PGD8_HUMAN,tr|H0YHB7|H0YHB7_HUMAN,tr|A0A6Q8PF05|A0A6Q8PF05_HUMAN,tr|B4DM51|B4DM51_HUMAN" 7 1538.73 1.47 130004 10078 4 1538.724537 385.6898 RNA-binding protein Musashi homolog 1 OS=Homo sapiens OX=9606 GN=MSI1 PE=1 SV=1 6 2128.6 - 723810 - - - -3.5484 - 1.499 0.15 - 41.2 1 2 0 -0.0055 12 0 0 0 8.06E+07 5.50E+07 - - - 0.6833 0.9725 221125_WJC_METTL3_EV_vs_WT_F09.10082.10082.4 0.00466 Nov-66 K.VC[160.03]EIHFHEINNK[136.11].M "sp|O43347|MSI1H_HUMAN,sp|Q96DH6|MSI2H_HUMAN,tr|B4DHE8|B4DHE8_HUMAN,tr|A0A6Q8PGD8|A0A6Q8PGD8_HUMAN,tr|H0YHB7|H0YHB7_HUMAN,tr|A0A6Q8PF05|A0A6Q8PF05_HUMAN,tr|B4DM51|B4DM51_HUMAN" 7 1546.7442 1.47 130008 10082 4 1546.730855 387.6933 RNA-binding protein Musashi homolog 1 OS=Homo sapiens OX=9606 GN=MSI1 PE=1 SV=1 6 2129 - 501697 - - - -8.6259 - 1.912 0.367 - 99.5 1 2 0 -0.0133 12 0 0 0 8.06E+07 5.50E+07 - - - 2.662 0.9997 221125_WJC_METTL3_EV_vs_WT_F09.10087.10087.3 0.000504 Dec-44 K.VC[160.03]EIHFHEINNK[136.11].M "sp|O43347|MSI1H_HUMAN,sp|Q96DH6|MSI2H_HUMAN,tr|B4DHE8|B4DHE8_HUMAN,tr|A0A6Q8PGD8|A0A6Q8PGD8_HUMAN,tr|H0YHB7|H0YHB7_HUMAN,tr|A0A6Q8PF05|A0A6Q8PF05_HUMAN,tr|B4DM51|B4DM51_HUMAN" 7 1546.7442 1.7 130011 10087 3 1546.739628 516.5887 RNA-binding protein Musashi homolog 1 OS=Homo sapiens OX=9606 GN=MSI1 PE=1 SV=1 6 2129.7 - 1.05E+06 - - - -2.9539 - 2.376 0.394 - 197.8 1 2 0 -0.0046 12 0 0 0 9.60E+07 5.66E+07 - - - 5.3303 0.8973 221125_WJC_METTL3_EV_vs_WT_F09.10090.10090.2 0.644 26-Jul K.EGLELPEDEEEKKK.Q "sp|Q58FG0|HS905_HUMAN,sp|P08238|HS90B_HUMAN,sp|Q58FF7|H90B3_HUMAN,sp|P07900|HS90A_HUMAN" 4 1671.8203 0.97 130014 10090 2 1671.815283 836.9174 Putative heat shock protein HSP 90-alpha A5 OS=Homo sapiens OX=9606 GN=HSP90AA5P PE=2 SV=1 4.31 2130.1 - 238093 - - - -3.0075 - 1.594 0.201 - 117.9 1 2 1 -0.005 14 0 0 0 2.60E+06 2.67E+06 - - - 1.694 1 221125_WJC_METTL3_EV_vs_WT_F09.10095.10095.2 5.26E-11 20/30 K.STAGDTHLGGEDFDNR[166.11].M "sp|P54652|HSP72_HUMAN,sp|P11142|HSP7C_HUMAN,tr|E9PKE3|E9PKE3_HUMAN,tr|E9PN89|E9PN89_HUMAN" 4 1700.7266 0.16 130017 10095 2 1700.722816 851.3706 Heat shock-related 70 kDa protein 2 OS=Homo sapiens OX=9606 GN=HSPA2 PE=1 SV=1 4.22 2130.7 - 1.02E+06 - - - -2.2108 - 3.519 0.727 - 858.1 1 2 0 -0.0038 16 0 0 0 4.52E+07 2.78E+08 - - - 7.5027 0.9936 221125_WJC_METTL3_EV_vs_WT_F09.10096.10096.4 0.0143 Oct-72 K.YSIWC[160.03]STEHGNK[136.11]R[166.11].L "sp|Q9BYJ9|YTHD1_HUMAN,sp|Q7Z739|YTHD3_HUMAN,tr|A0A087X0Q1|A0A087X0Q1_HUMAN,tr|A0A024R7W5|A0A024R7W5_HUMAN,tr|A0A087WY31|A0A087WY31_HUMAN" 5 1654.7641 1.86 130018 10096 4 1654.755372 414.6983 YTH domain-containing family protein 1 OS=Homo sapiens OX=9606 GN=YTHDF1 PE=1 SV=1 8.21 2130.8 - 392320 - - - -5.2708 - 1.866 0.345 - 77.1 1 2 0 -0.0087 13 0 0 0 9.06E+06 4.86E+06 - - - 2.4577 0.9999 221125_WJC_METTL3_EV_vs_WT_F09.10101.10101.3 1.56E-06 15/60 K.NSTGSGHSAQELPTIR.T "sp|O94763|RMP_HUMAN,tr|I3L280|I3L280_HUMAN" 2 1653.8071 1.74 130021 10101 3 1653.803495 552.2763 Unconventional prefoldin RPB5 interactor 1 OS=Homo sapiens OX=9606 GN=URI1 PE=1 SV=3 6.75 2131.5 - 501363 - - - -2.1562 - 2.682 0.491 - 289.1 1 2 0 -0.0036 16 0 0 0 2.46E+07 1.42E+07 - - - 6.5446 1 221125_WJC_METTL3_EV_vs_WT_F09.10102.10102.3 1.32E-08 16/60 K.STAGDTHLGGEDFDNR.M "sp|P54652|HSP72_HUMAN,sp|P11142|HSP7C_HUMAN,tr|E9PKE3|E9PKE3_HUMAN,tr|E9PN89|E9PN89_HUMAN" 4 1690.7183 0.17 130022 10102 3 1690.716096 564.58 Heat shock-related 70 kDa protein 2 OS=Homo sapiens OX=9606 GN=HSPA2 PE=1 SV=1 4.22 2131.5 - 6.05E+06 - - - -1.3071 - 3.176 0.63 - 353.9 1 2 0 -0.0022 16 0 0 0 7.15E+08 4.27E+09 - - - 8.5284 1 221125_WJC_METTL3_EV_vs_WT_F09.10105.10105.3 9.62E-08 15/52 K.GAEHITTYTFNTHK[136.11].A sp|Q7Z7K6|CENPV_HUMAN 1 1626.7882 0.9 130025 10105 3 1626.786734 543.27 Centromere protein V OS=Homo sapiens OX=9606 GN=CENPV PE=1 SV=1 6.92 2131.9 - 747862 - - - -0.8827 - 2.644 0.602 - 247.6 1 2 0 -0.0014 14 0 0 0 1.42E+07 1.57E+07 - - - 7.8352 0.9997 221125_WJC_METTL3_EV_vs_WT_F09.10106.10106.3 5.61E-07 Nov-52 K.GAEHITTYTFNTHK.A sp|Q7Z7K6|CENPV_HUMAN 1 1618.774 0.9 130026 10106 3 1618.768205 540.5986 Centromere protein V OS=Homo sapiens OX=9606 GN=CENPV PE=1 SV=1 6.92 2132.1 - 627588 - - - -3.5613 - 2.167 0.485 - 112.4 1 2 0 -0.0058 14 0 0 0 1.42E+07 1.57E+07 - - - 6.0009 1 221125_WJC_METTL3_EV_vs_WT_F09.10107.10107.3 3.02E-05 14/48 K.YSIWC[160.03]STEHGNKR.L "sp|Q9BYJ9|YTHD1_HUMAN,sp|Q7Z739|YTHD3_HUMAN,tr|A0A087X0Q1|A0A087X0Q1_HUMAN,tr|A0A024R7W5|A0A024R7W5_HUMAN,tr|A0A087WY31|A0A087WY31_HUMAN" 5 1636.7416 5.95 130027 10107 3 1636.740331 546.5878 YTH domain-containing family protein 1 OS=Homo sapiens OX=9606 GN=YTHDF1 PE=1 SV=1 8.21 2132.2 - 453097 - - - -0.79 - 2.517 0.521 - 238.7 1 2 0 -0.0013 13 0 0 0 7.76E+06 1.30E+06 - - - 6.851 1 221125_WJC_METTL3_EV_vs_WT_F09.10115.10115.2 7.17E-12 18/30 K.STAGDTHLGGEDFDNR.M "sp|P54652|HSP72_HUMAN,sp|P11142|HSP7C_HUMAN,tr|E9PKE3|E9PKE3_HUMAN,tr|E9PN89|E9PN89_HUMAN" 4 1690.7183 0.16 130033 10115 2 1690.717289 846.3664 Heat shock-related 70 kDa protein 2 OS=Homo sapiens OX=9606 GN=HSPA2 PE=1 SV=1 4.22 2133.1 - 631462 - - - -0.6015 - 3.449 0.765 - 826.8 1 2 0 -0.001 16 0 0 0 4.52E+07 2.78E+08 - - - 7.7349 1 221125_WJC_METTL3_EV_vs_WT_F09.10120.10120.2 3.01E-07 18/26 T.AGDTHLGGEDFDNR[166.11].L "sp|P48741|HSP77_HUMAN,sp|P54652|HSP72_HUMAN,sp|P0DMV8|HS71A_HUMAN,sp|P34931|HS71L_HUMAN,sp|P11142|HSP7C_HUMAN,sp|P0DMV9|HS71B_HUMAN,sp|P17066|HSP76_HUMAN,tr|E9PKE3|E9PKE3_HUMAN,tr|E9PN89|E9PN89_HUMAN,tr|Q53FA3|Q53FA3_HUMAN,tr|V9GZ37|V9GZ37_HUMAN,tr|A0A0G2JIW1|A0A0G2JIW1_HUMAN" 12 1512.6469 0.06 130036 10120 2 1512.641985 757.3307 Putative heat shock 70 kDa protein 7 OS=Homo sapiens OX=9606 GN=HSPA7 PE=5 SV=2 4.22 2133.8 - 851781 - - - -3.2288 - 2.689 0.632 - 1038.3 1 1 0 -0.0049 14 0 0 0 3.17E+06 4.95E+07 - - - 6.1897 1 221125_WJC_METTL3_EV_vs_WT_F09.10124.10124.2 8.82E-08 30-Dec K.RPELLTHSTTEVTQPR.T "sp|P78347|GTF2I_HUMAN,tr|A0A494C0Q7|A0A494C0Q7_HUMAN,tr|A0A494C1K3|A0A494C1K3_HUMAN" 3 1863.9803 1.85 130038 10124 2 1863.977778 932.9974 General transcription factor II-I OS=Homo sapiens OX=9606 GN=GTF2I PE=1 SV=2 6.76 2134.3 - 812205 - - - -1.3396 - 2.813 0.631 - 67.2 1 2 0 -0.0025 16 0 0 0 3.18E+07 1.72E+07 - - - 6.2435 0.9845 221125_WJC_METTL3_EV_vs_WT_F09.10130.10130.4 0.112 Nov-78 K.GAEHITTYTFNTHK.A sp|Q7Z7K6|CENPV_HUMAN 1 1618.774 0.99 130042 10130 4 1618.769342 405.7008 Centromere protein V OS=Homo sapiens OX=9606 GN=CENPV PE=1 SV=1 6.92 2135 - 709563 - - - -2.859 - 1.556 0.228 - 64.1 1 2 0 -0.0046 14 0 0 0 1.12E+07 1.13E+07 - - - 1.3701 0.9961 221125_WJC_METTL3_EV_vs_WT_F09.10138.10138.3 0.00187 17/60 K.R[166.11]PELLTHSTTEVTQPR.T "sp|P78347|GTF2I_HUMAN,tr|A0A494C0Q7|A0A494C0Q7_HUMAN,tr|A0A494C1K3|A0A494C1K3_HUMAN" 3 1873.9885 - 130044 10138 3 1873.97631 625.6701 General transcription factor II-I OS=Homo sapiens OX=9606 GN=GTF2I PE=1 SV=2 6.76 2136 - 451440 - - - -6.5289 - 3.052 0.356 - 473 1 2 0 -0.0122 16 0 0 0 - - - - - 5.3686 0.997 221125_WJC_METTL3_EV_vs_WT_F09.10142.10142.3 0.00346 13/68 K.SIHANFSSGVGTTAASSK[136.11].N "sp|Q8IWZ3|ANKH1_HUMAN,tr|A0A0A0MQZ8|A0A0A0MQZ8_HUMAN,tr|H0Y472|H0Y472_HUMAN,tr|H0Y7Y3|H0Y7Y3_HUMAN,tr|H0Y4P6|H0Y4P6_HUMAN,tr|H0Y785|H0Y785_HUMAN" 6 1728.8522 1.17 130045 10142 3 1728.841414 577.2914 Ankyrin repeat and KH domain-containing protein 1 OS=Homo sapiens OX=9606 GN=ANKHD1 PE=1 SV=1 8.49 2136.6 - 455181 - - - -6.2544 - 2.449 0.419 - 207.3 1 2 0 -0.0108 18 0 0 0 2.18E+07 1.87E+07 - - - 5.4388 0.9998 221125_WJC_METTL3_EV_vs_WT_F09.10144.10144.2 6.27E-05 30-Aug K.R[166.11]PELLTHSTTEVTQPR[166.11].T "sp|P78347|GTF2I_HUMAN,tr|A0A494C0Q7|A0A494C0Q7_HUMAN,tr|A0A494C1K3|A0A494C1K3_HUMAN" 3 1883.9968 1.85 130046 10144 2 1883.993669 943.0057 General transcription factor II-I OS=Homo sapiens OX=9606 GN=GTF2I PE=1 SV=2 6.76 2136.8 - 503676 - - - -1.6699 - 2.261 0.5 - 27.3 1 2 0 -0.0031 16 0 0 0 3.18E+07 1.72E+07 - - - 4.7387 1 221125_WJC_METTL3_EV_vs_WT_F09.10151.10151.3 4.45E-14 29/104 A.GGPAPAAGAAPAGGPAPSTAAAPAEEK.K sp|P05386|RLA1_HUMAN 1 2241.1026 2.93 130049 10151 3 2241.096538 748.0415 60S acidic ribosomal protein P1 OS=Homo sapiens OX=9606 GN=RPLP1 PE=1 SV=1 4.53 2137.6 - 1.27E+06 - - - -2.6938 - 5.01 0.686 - 845.7 1 1 0 -0.006 27 0 0 0 4.58E+07 1.56E+07 - - - 9.8939 1 221125_WJC_METTL3_EV_vs_WT_F09.10158.10158.2 3.44E-08 14/38 R.SDSPVPTAPTSGGPK[136.11]PSTAS.A "sp|Q86U44|MTA70_HUMAN,tr|B4E349|B4E349_HUMAN,tr|F5H6D8|F5H6D8_HUMAN,tr|B4DTN4|B4DTN4_HUMAN" 4 1847.8992 0.03 130053 10158 2 1847.892593 924.9569 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 5.55 2138.5 - 1.94E+06 - - - -3.5954 - 2.707 0.611 - 342.7 1 1 0 -0.0066 20 0 0 0 3.11E+07 1.07E+09 - - - 6.0001 1 221125_WJC_METTL3_EV_vs_WT_F09.10163.10163.3 1.92E-06 15/60 K.ATAGDTHLGGEDFDNR.L "sp|P48741|HSP77_HUMAN,sp|P0DMV8|HS71A_HUMAN,sp|P34931|HS71L_HUMAN,sp|P0DMV9|HS71B_HUMAN,sp|P17066|HSP76_HUMAN,tr|Q53FA3|Q53FA3_HUMAN,tr|V9GZ37|V9GZ37_HUMAN,tr|A0A0G2JIW1|A0A0G2JIW1_HUMAN" 8 1674.7234 0.16 130055 10163 3 1674.71774 559.2484 Putative heat shock 70 kDa protein 7 OS=Homo sapiens OX=9606 GN=HSPA7 PE=5 SV=2 4.22 2139.2 - 981936 - - - -3.3743 - 3.034 0.633 - 321.4 1 2 0 -0.0057 16 0 0 0 1.24E+08 7.90E+08 - - - 8.4436 0.9999 221125_WJC_METTL3_EV_vs_WT_F09.10164.10164.3 8.36E-07 18/68 K.SIHANFSSGVGTTAASSK.N "sp|Q8IWZ3|ANKH1_HUMAN,tr|A0A0A0MQZ8|A0A0A0MQZ8_HUMAN,tr|H0Y472|H0Y472_HUMAN,tr|H0Y7Y3|H0Y7Y3_HUMAN,tr|H0Y4P6|H0Y4P6_HUMAN,tr|H0Y785|H0Y785_HUMAN" 6 1720.838 1.17 130056 10164 3 1720.833186 574.62 Ankyrin repeat and KH domain-containing protein 1 OS=Homo sapiens OX=9606 GN=ANKHD1 PE=1 SV=1 8.49 2139.3 - 962234 - - - -2.8132 - 3.305 0.465 - 195.1 1 2 0 -0.0048 18 0 0 0 2.18E+07 1.87E+07 - - - 6.6997 1 221125_WJC_METTL3_EV_vs_WT_F09.10170.10170.2 3.40E-08 14/30 K.ATAGDTHLGGEDFDNR[166.11].L "sp|P48741|HSP77_HUMAN,sp|P0DMV8|HS71A_HUMAN,sp|P34931|HS71L_HUMAN,sp|P0DMV9|HS71B_HUMAN,sp|P17066|HSP76_HUMAN,tr|Q53FA3|Q53FA3_HUMAN,tr|V9GZ37|V9GZ37_HUMAN,tr|A0A0G2JIW1|A0A0G2JIW1_HUMAN" 8 1684.7317 0.05 130060 10170 2 1684.734426 843.3731 Putative heat shock 70 kDa protein 7 OS=Homo sapiens OX=9606 GN=HSPA7 PE=5 SV=2 4.22 2140.1 - 807532 - - - 1.6412 - 2.703 0.685 - 501.2 1 2 0 0.0028 16 0 0 0 2.15E+06 4.41E+07 - - - 6.5442 0.9999 221125_WJC_METTL3_EV_vs_WT_F09.10174.10174.3 2.45E-06 13/60 K.ATAGDTHLGGEDFDNR[166.11].L "sp|P48741|HSP77_HUMAN,sp|P0DMV8|HS71A_HUMAN,sp|P34931|HS71L_HUMAN,sp|P0DMV9|HS71B_HUMAN,sp|P17066|HSP76_HUMAN,tr|Q53FA3|Q53FA3_HUMAN,tr|V9GZ37|V9GZ37_HUMAN,tr|A0A0G2JIW1|A0A0G2JIW1_HUMAN" 8 1684.7317 0.16 130062 10174 3 1684.727185 562.5845 Putative heat shock 70 kDa protein 7 OS=Homo sapiens OX=9606 GN=HSPA7 PE=5 SV=2 4.22 2140.5 - 1.63E+07 - - - -2.6568 - 2.563 0.529 - 216.2 1 2 0 -0.0045 16 0 0 0 1.24E+08 7.90E+08 - - - 6.8515 1 221125_WJC_METTL3_EV_vs_WT_F09.10175.10175.3 1.41E-10 20/72 R.VDQIIMAK[136.11]PAGGPK[136.11]PPSGK[136.11].K "sp|P50990|TCPQ_HUMAN,tr|H7C2U0|H7C2U0_HUMAN" 2 1914.0823 0.05 130063 10175 3 1914.078135 639.0347 T-complex protein 1 subunit theta OS=Homo sapiens OX=9606 GN=CCT8 PE=1 SV=4 9.7 2140.6 - 2.46E+06 - - - -2.1781 - 3.587 0.575 - 351.8 1 2 0 -0.0042 19 0 0 0 2.69E+06 5.40E+07 - - - 8.0876 0.9998 221125_WJC_METTL3_EV_vs_WT_F09.10178.10178.4 3.41E-05 15/108 R.VDQIIMAK[136.11]PAGGPK[136.11]PPSGK[136.11].K "sp|P50990|TCPQ_HUMAN,tr|H7C2U0|H7C2U0_HUMAN" 2 1914.0823 0.15 130064 10178 4 1914.077067 479.5279 T-complex protein 1 subunit theta OS=Homo sapiens OX=9606 GN=CCT8 PE=1 SV=4 9.7 2141 - 4.39E+06 - - - -2.736 - 2.454 0.442 - 129.1 1 2 0 -0.0052 19 0 0 0 2.44E+07 1.59E+08 - - - 3.3754 0.9649 221125_WJC_METTL3_EV_vs_WT_F09.10190.10190.3 0.000518 Jul-40 M.SDTWSSIQAHK[136.11].K "sp|Q86U44|MTA70_HUMAN,tr|B4E349|B4E349_HUMAN,tr|F5H6D8|F5H6D8_HUMAN,tr|B4DTN4|B4DTN4_HUMAN" 4 1266.6084 0 130070 10190 3 1266.604313 423.2101 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 6.46 2142.6 - 831178 - - - -3.2386 - 1.612 0.183 - 93.3 1 2 0 -0.0041 11 0 0 0 5.72E+04 1.65E+07 - - - 1.9356 0.9999 221125_WJC_METTL3_EV_vs_WT_F09.10205.10205.4 4.24E-07 17/108 K.GVPHPEDDHSQVEGPESLR.- "sp|Q6P996|PDXD1_HUMAN,tr|H3BND4|H3BND4_HUMAN" 2 2083.9559 1.92 130080 10205 4 2083.946758 521.9963 Pyridoxal-dependent decarboxylase domain-containing protein 1 OS=Homo sapiens OX=9606 GN=PDXDC1 PE=1 SV=2 4.49 2144.4 - 442785 - - - -4.3916 - 2.707 0.578 - 183.3 1 2 0 -0.0092 19 0 0 0 1.59E+07 8.32E+06 - - - 4.5912 1 221125_WJC_METTL3_EV_vs_WT_F09.10208.10208.4 4.29E-09 19/72 K.YNIWC[160.03]STEHGNKR.L sp|Q9Y5A9|YTHD2_HUMAN 1 1663.7525 1.28 130081 10208 4 1663.747118 416.9454 YTH domain-containing family protein 2 OS=Homo sapiens OX=9606 GN=YTHDF2 PE=1 SV=2 8.21 2144.8 - 774026 - - - -3.2487 - 3.149 0.617 - 362.1 1 2 0 -0.0054 13 0 0 0 3.11E+07 2.42E+07 - - - 5.0202 1 221125_WJC_METTL3_EV_vs_WT_F09.10214.10214.4 0.000635 16/72 K.YNIWC[160.03]STEHGNK[136.11]R[166.11].L sp|Q9Y5A9|YTHD2_HUMAN 1 1681.775 1.28 130085 10214 4 1681.773266 421.451 YTH domain-containing family protein 2 OS=Homo sapiens OX=9606 GN=YTHDF2 PE=1 SV=2 8.21 2145.7 - 747691 - - - -1.0275 - 2.733 0.564 - 233.7 1 2 0 -0.0017 13 0 0 0 3.11E+07 2.44E+07 - - - 4.5073 1 221125_WJC_METTL3_EV_vs_WT_F09.10219.10219.3 4.01E-06 14/48 K.YNIWC[160.03]STEHGNKR.L sp|Q9Y5A9|YTHD2_HUMAN 1 1663.7525 1.49 130088 10219 3 1663.751831 555.5915 YTH domain-containing family protein 2 OS=Homo sapiens OX=9606 GN=YTHDF2 PE=1 SV=2 8.21 2146.2 - 1.43E+06 - - - -0.4159 - 2.454 0.596 - 212.5 1 2 0 -0.0007 13 0 0 0 2.43E+07 1.63E+07 - - - 7.6186 0.9994 221125_WJC_METTL3_EV_vs_WT_F09.10221.10221.3 0.000269 Sep-44 R.SRTEAESWYQTK.Y "sp|P13647|K2C5_HUMAN,tr|H0YI76|H0YI76_HUMAN,tr|H0YIN9|H0YIN9_HUMAN" 3 1484.6896 1.56 130090 10221 3 1484.686193 495.9038 "Keratin, type II cytoskeletal 5 OS=Homo sapiens OX=9606 GN=KRT5 PE=1 SV=3" 5.86 2146.4 - 692963 - - - -2.2759 - 2.166 0.449 - 121.2 1 2 1 -0.0034 12 0 0 0 1.77E+07 1.14E+07 - - - 5.6873 0.9196 221125_WJC_METTL3_EV_vs_WT_F09.10226.10226.3 0.00452 Nov-76 R.SDSPVPTAPTSGGPK[136.11]PSTAS.A "sp|Q86U44|MTA70_HUMAN,tr|B4E349|B4E349_HUMAN,tr|F5H6D8|F5H6D8_HUMAN,tr|B4DTN4|B4DTN4_HUMAN" 4 1847.8992 0.03 130093 10226 3 1847.895663 616.9737 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 5.55 2147.1 - 7.41E+06 - - - -1.9341 - 1.926 0.334 - 107.5 1 1 0 -0.0036 20 0 0 0 6.47E+06 2.42E+08 - - - 3.8529 0.9999 221125_WJC_METTL3_EV_vs_WT_F09.10229.10229.3 0.000298 18/52 K.R[166.11]VSISEGDDK[136.11]IEYR[166.11].A "sp|P22087|FBRL_HUMAN,tr|M0R299|M0R299_HUMAN,tr|M0R0P1|M0R0P1_HUMAN,tr|M0R1H0|M0R1H0_HUMAN,tr|M0QXL5|M0QXL5_HUMAN,tr|M0R2Q4|M0R2Q4_HUMAN,tr|M0R2B0|M0R2B0_HUMAN,tr|M0R2U2|M0R2U2_HUMAN" 8 1693.863 0.72 130096 10229 3 1693.863271 565.6283 rRNA 2'-O-methyltransferase fibrillarin OS=Homo sapiens OX=9606 GN=FBL PE=1 SV=2 4.78 2147.4 - 599608 - - - 0.1877 - 3.325 0.544 - 552.9 1 2 1 0.0003 14 0 0 0 1.49E+07 2.08E+07 - - - 7.7979 0.9133 221125_WJC_METTL3_EV_vs_WT_F09.10238.10238.3 0.00487 Jul-60 R.DGQVINETSQHHDDLE.- sp|P08670|VIME_HUMAN 1 1835.7922 - 130103 10238 3 1835.787404 612.938 Vimentin OS=Homo sapiens OX=9606 GN=VIM PE=1 SV=4 4.28 2148.6 - 354267 - - - -2.612 - 1.579 0.125 - 40.2 1 2 0 -0.0048 16 0 0 0 - - - - - 1.1044 0.9999 221125_WJC_METTL3_EV_vs_WT_F09.10242.10242.4 1.01E-06 17/78 K.R[166.11]VSISEGDDK[136.11]IEYR[166.11].A "sp|P22087|FBRL_HUMAN,tr|M0R299|M0R299_HUMAN,tr|M0R0P1|M0R0P1_HUMAN,tr|M0R1H0|M0R1H0_HUMAN,tr|M0QXL5|M0QXL5_HUMAN,tr|M0R2Q4|M0R2Q4_HUMAN,tr|M0R2B0|M0R2B0_HUMAN,tr|M0R2U2|M0R2U2_HUMAN" 8 1693.863 0.71 130105 10242 4 1693.859663 424.473 rRNA 2'-O-methyltransferase fibrillarin OS=Homo sapiens OX=9606 GN=FBL PE=1 SV=2 4.78 2149 - 523484 - - - -1.9423 - 3.083 0.557 - 383.2 1 2 1 -0.0033 14 0 0 0 8.55E+06 1.21E+07 - - - 4.483 0.8893 221125_WJC_METTL3_EV_vs_WT_F09.10244.10244.3 0.51 Jul-72 R.LK[136.11]EQGQAPITPQQGQALAK[136.11].Q sp|P84095|RHOG_HUMAN 1 2021.124 0.84 130107 10244 3 2021.123284 674.7153 Rho-related GTP-binding protein RhoG OS=Homo sapiens OX=9606 GN=RHOG PE=1 SV=1 8.59 2149.3 - 153129 - - - -0.3736 - 1.291 0.185 - 29.7 1 2 1 -0.0008 19 0 0 0 7.76E+06 9.20E+06 - - - 1.2299 0.9784 221125_WJC_METTL3_EV_vs_WT_F09.10249.10249.2 1.7 12-Apr R.LASYLDK.V "sp|Q04695|K1C17_HUMAN,sp|Q99456|K1C12_HUMAN,sp|P13645|K1C10_HUMAN,sp|P02533|K1C14_HUMAN,sp|P08727|K1C19_HUMAN,sp|P35527|K1C9_HUMAN,sp|P08779|K1C16_HUMAN,sp|P19012|K1C15_HUMAN,tr|K7EPJ9|K7EPJ9_HUMAN,tr|C9JM50|C9JM50_HUMAN,tr|A0A1B0GVI3|A0A1B0GVI3_HUMAN,tr|A0A3B3ITG2|A0A3B3ITG2_HUMAN" 12 808.4331 47.94 130110 10249 2 808.43391 405.2238 "Keratin, type I cytoskeletal 17 OS=Homo sapiens OX=9606 GN=KRT17 PE=1 SV=2" 5.83 2150 - 343037 - - - 1.039 - 0.921 0.224 - 40.2 2 2 0 0.0008 7 0 0 0 1.73E+07 3.62E+05 - - - 0.3 1 221125_WJC_METTL3_EV_vs_WT_F09.10251.10251.4 1.57E-06 10/108 K.GVPHPEDDHSQVEGPESLR[166.11].- "sp|Q6P996|PDXD1_HUMAN,tr|H3BND4|H3BND4_HUMAN" 2 2093.9642 1.99 130112 10251 4 2093.966052 524.4983 Pyridoxal-dependent decarboxylase domain-containing protein 1 OS=Homo sapiens OX=9606 GN=PDXDC1 PE=1 SV=2 4.49 2150.2 - 323759 - - - 0.894 - 2.082 0.561 - 48.3 1 2 0 0.0019 19 0 0 0 1.52E+07 7.62E+06 - - - 4.3565 1 221125_WJC_METTL3_EV_vs_WT_F09.10255.10255.3 7.90E-08 14/60 K.STAGDTHLGGEDFDNR[166.11].M "sp|P54652|HSP72_HUMAN,sp|P11142|HSP7C_HUMAN,tr|E9PKE3|E9PKE3_HUMAN,tr|E9PN89|E9PN89_HUMAN" 4 1700.7266 0.18 130115 10255 3 1700.726302 567.9161 Heat shock-related 70 kDa protein 2 OS=Homo sapiens OX=9606 GN=HSPA2 PE=1 SV=1 4.22 2150.8 - 1.08E+06 - - - -0.1611 - 2.509 0.565 - 247.8 1 2 0 -0.0003 16 0 0 0 4.65E+06 2.60E+07 - - - 7.1994 1 221125_WJC_METTL3_EV_vs_WT_F09.10257.10257.3 2.48E-09 14/68 K.TC[160.03]NTNPHLNALSTDSAC[160.03]R.R "sp|Q9NZB2|F120A_HUMAN,tr|A0A0C4DG79|A0A0C4DG79_HUMAN" 2 2030.8898 1.16 130116 10257 3 2030.890497 677.9706 Constitutive coactivator of PPAR-gamma-like protein 1 OS=Homo sapiens OX=9606 GN=FAM120A PE=1 SV=2 6.4 2151 - 448191 - - - 0.3324 - 3.178 0.692 - 260.8 1 2 0 0.0007 18 0 0 0 9.09E+06 7.83E+06 - - - 9.1341 0.9455 221125_WJC_METTL3_EV_vs_WT_F09.10280.10280.3 0.000584 Sep-72 R.RLLEGEDAHLSSQQASGQS.Y sp|P08779|K1C16_HUMAN 1 2011.9559 11.41 130132 10280 3 2011.962344 671.6592 "Keratin, type I cytoskeletal 16 OS=Homo sapiens OX=9606 GN=KRT16 PE=1 SV=4" 4.65 2153.8 - 218652 - - - 3.1979 - 2.133 0.412 - 99 1 1 0 0.0064 19 0 0 0 1.19E+07 1.04E+06 - - - 4.9927 0.9999 221125_WJC_METTL3_EV_vs_WT_F09.10285.10285.4 1.21E-05 17/78 K.RVSISEGDDKIEYR.A "sp|P22087|FBRL_HUMAN,tr|M0R299|M0R299_HUMAN,tr|M0R0P1|M0R0P1_HUMAN,tr|M0R1H0|M0R1H0_HUMAN,tr|M0QXL5|M0QXL5_HUMAN,tr|M0R2Q4|M0R2Q4_HUMAN,tr|M0R2B0|M0R2B0_HUMAN,tr|M0R2U2|M0R2U2_HUMAN" 8 1665.8322 0.67 130135 10285 4 1665.830979 417.4653 rRNA 2'-O-methyltransferase fibrillarin OS=Homo sapiens OX=9606 GN=FBL PE=1 SV=2 4.78 2154.4 - 278205 - - - -0.7408 - 3.18 0.507 - 311.3 1 2 1 -0.0012 14 0 0 0 8.69E+06 1.30E+07 - - - 4.0596 0.9999 221125_WJC_METTL3_EV_vs_WT_F09.10291.10291.3 1.99E-05 Nov-64 K.SQEGTQEVSVRPSVIQK.L "sp|Q9HCK1|ZDBF2_HUMAN,tr|A0A3B3ISF7|A0A3B3ISF7_HUMAN,tr|A0A3B3ISJ7|A0A3B3ISJ7_HUMAN,tr|A0A3B3ITZ5|A0A3B3ITZ5_HUMAN,tr|A0A3B3IRN6|A0A3B3IRN6_HUMAN,tr|N0DVX5|N0DVX5_HUMAN" 6 1870.9749 1.56 130139 10291 3 1870.977056 624.6656 DBF4-type zinc finger-containing protein 2 OS=Homo sapiens OX=9606 GN=ZDBF2 PE=1 SV=3 5.86 2155.2 - 414193 - - - 1.1764 - 2.231 0.45 - 126.9 1 2 0 0.0022 17 0 0 0 7.42E+06 4.74E+06 - - - 5.5837 1 221125_WJC_METTL3_EV_vs_WT_F09.10300.10300.3 0.000232 13/52 R.K[136.11]NPLPPSVGVVDK[136.11]K[136.11].E sp|Q8NC51|PAIRB_HUMAN 1 1500.909 0.72 130146 10300 3 1500.911564 501.3103 Plasminogen activator inhibitor 1 RNA-binding protein OS=Homo sapiens OX=9606 GN=SERBP1 PE=1 SV=2 9.7 2156.3 - 228365 - - - 1.699 - 3.05 0.493 - 237.5 1 2 0 0.0026 14 0 0 0 1.59E+07 2.20E+07 - - - 6.9993 0.9968 221125_WJC_METTL3_EV_vs_WT_F09.10301.10301.4 0.0295 Aug-78 R.LLEGEDAHLTQYKK.E "sp|Q04695|K1C17_HUMAN,tr|A0A3B3IS58|A0A3B3IS58_HUMAN,tr|F5GWP8|F5GWP8_HUMAN" 3 1643.8519 122.5 130147 10301 4 1643.854704 411.9702 "Keratin, type I cytoskeletal 17 OS=Homo sapiens OX=9606 GN=KRT17 PE=1 SV=2" 5.45 2156.5 - 308951 - - - 1.7143 - 1.076 0.281 - 19.4 1 2 0 0.0028 14 0 0 0 8.85E+06 7.23E+04 - - - 1.6977 0.995 221125_WJC_METTL3_EV_vs_WT_F09.10307.10307.3 0.000594 Aug-60 K.RPELLTHSTTEVTQPR.T "sp|P78347|GTF2I_HUMAN,tr|A0A494C0Q7|A0A494C0Q7_HUMAN,tr|A0A494C1K3|A0A494C1K3_HUMAN" 3 1863.9803 1.5 130151 10307 3 1863.993851 622.334 General transcription factor II-I OS=Homo sapiens OX=9606 GN=GTF2I PE=1 SV=2 6.76 2157.3 - 190087 - - - 7.2833 - 2.037 0.459 - 58.4 1 2 0 0.0136 16 0 0 0 2.06E+09 1.38E+09 - - - 5.4792 1 221125_WJC_METTL3_EV_vs_WT_F09.10314.10314.3 8.27E-08 14/56 K.HGSYEDAVHSGALND.- "sp|P17987|TCPA_HUMAN,tr|F5H282|F5H282_HUMAN,tr|E7EQR6|E7EQR6_HUMAN" 3 1570.6648 - 130156 10314 3 1570.668922 524.5622 T-complex protein 1 subunit alpha OS=Homo sapiens OX=9606 GN=TCP1 PE=1 SV=1 4.72 2158.2 - 319757 - - - 2.6155 - 2.568 0.568 - 221.3 1 2 0 0.0041 15 0 0 0 - - - - - 7.3325 0.9999 221125_WJC_METTL3_EV_vs_WT_F09.10315.10315.4 8.30E-05 Nov-96 R.ATSLGRPEEEEDELAHR.C "sp|P36551|HEM6_HUMAN,tr|D6RER6|D6RER6_HUMAN" 2 1937.9079 1.51 130157 10315 4 1937.910902 485.4843 "Oxygen-dependent coproporphyrinogen-III oxidase, mitochondrial OS=Homo sapiens OX=9606 GN=CPOX PE=1 SV=3" 4.41 2158.4 - 378631 - - - 1.5501 - 2 0.416 - 99.9 1 2 0 0.003 17 0 0 0 2.19E+07 1.45E+07 - - - 3.0867 1 221125_WJC_METTL3_EV_vs_WT_F09.10318.10318.2 1.24E-05 14/26 R.SSQSSSQQFSGIGR[166.11].S "sp|Q92841|DDX17_HUMAN,tr|A0A5H1ZRQ2|A0A5H1ZRQ2_HUMAN,tr|A0A1X7SBZ2|A0A1X7SBZ2_HUMAN" 3 1464.6833 1.09 130160 10318 2 1464.687634 733.3489 Probable ATP-dependent RNA helicase DDX17 OS=Homo sapiens OX=9606 GN=DDX17 PE=1 SV=2 9.47 2158.8 - 188728 - - - 2.9904 - 2.844 0.608 - 810 1 2 0 0.0044 14 0 0 0 7.63E+06 6.99E+06 - - - 6.1532 0.9998 221125_WJC_METTL3_EV_vs_WT_F09.10319.10319.3 0.000103 Nov-56 R.ETNPHHPPAWIASAR.L sp|O94906|PRP6_HUMAN 1 1682.8277 1.14 130161 10319 3 1682.833445 561.9499 Pre-mRNA-processing factor 6 OS=Homo sapiens OX=9606 GN=PRPF6 PE=1 SV=1 7.02 2158.9 - 188029 - - - 3.3919 - 1.936 0.513 - 140.9 1 2 0 0.0057 15 0 0 0 4.33E+06 3.81E+06 - - - 5.9817 0.9939 221125_WJC_METTL3_EV_vs_WT_F09.10322.10322.3 0.0273 Jun-60 K.R[166.11]PELLTHSTTEVTQPR[166.11].T "sp|P78347|GTF2I_HUMAN,tr|A0A494C0Q7|A0A494C0Q7_HUMAN,tr|A0A494C1K3|A0A494C1K3_HUMAN" 3 1883.9968 1.5 130164 10322 3 1883.993056 629.0062 General transcription factor II-I OS=Homo sapiens OX=9606 GN=GTF2I PE=1 SV=2 6.76 2159.3 - 144289 - - - -1.9952 - 1.469 0.265 - 29.9 1 2 0 -0.0038 16 0 0 0 2.06E+09 1.37E+09 - - - 2.4802 0.9867 221125_WJC_METTL3_EV_vs_WT_F09.10326.10326.2 1.14E-06 Aug-34 R.SDSPVPTAPTSGGPK[136.11]PST.A "sp|Q86U44|MTA70_HUMAN,tr|B4E349|B4E349_HUMAN,tr|F5H6D8|F5H6D8_HUMAN,tr|B4DTN4|B4DTN4_HUMAN" 4 1689.8301 0.19 130168 10326 2 1689.831904 845.9223 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 5.55 2159.8 - 72079.8 - - - 1.0705 - 1.686 0.547 - 117.2 1 1 0 0.0018 18 0 0 0 1.35E+06 7.17E+06 - - - 4.3648 1 221125_WJC_METTL3_EV_vs_WT_F09.10331.10331.2 1.53E-09 13/26 R.SSQSSSQQFSGIGR.S "sp|Q92841|DDX17_HUMAN,tr|A0A5H1ZRQ2|A0A5H1ZRQ2_HUMAN,tr|A0A1X7SBZ2|A0A1X7SBZ2_HUMAN" 3 1454.675 1.09 130171 10331 2 1454.679002 728.3448 Probable ATP-dependent RNA helicase DDX17 OS=Homo sapiens OX=9606 GN=DDX17 PE=1 SV=2 9.47 2160.5 - 348039 - - - 2.7621 - 2.884 0.644 - 781.6 1 2 0 0.004 14 0 0 0 7.63E+06 6.99E+06 - - - 6.4543 0.9997 221125_WJC_METTL3_EV_vs_WT_F09.10336.10336.3 0.0023 Sep-68 R.VNPHSLPDPEVNEQSSSK[136.11].G "sp|Q99575|POP1_HUMAN,tr|E5RK39|E5RK39_HUMAN" 2 1970.9425 1.24 130176 10336 3 1970.944292 657.9881 Ribonucleases P\MRP protein subunit POP1 OS=Homo sapiens OX=9606 GN=POP1 PE=1 SV=2 4.65 2161.1 - 73111.4 - - - 0.9097 - 1.749 0.385 - 81.2 1 2 0 0.0018 18 0 0 0 5.92E+06 4.79E+06 - - - 4.2239 0.9999 221125_WJC_METTL3_EV_vs_WT_F09.10341.10341.4 8.49E-05 15/96 R.ATSLGR[166.11]PEEEEDELAHR[166.11].C "sp|P36551|HEM6_HUMAN,tr|D6RER6|D6RER6_HUMAN" 2 1957.9244 2.07 130179 10341 4 1957.930697 490.4884 "Oxygen-dependent coproporphyrinogen-III oxidase, mitochondrial OS=Homo sapiens OX=9606 GN=CPOX PE=1 SV=3" 4.41 2161.9 - 462306 - - - 3.1968 - 2.616 0.499 - 159.9 1 2 0 0.0063 17 0 0 0 2.69E+07 1.30E+07 - - - 3.9014 0.9996 221125_WJC_METTL3_EV_vs_WT_F09.10342.10342.4 0.00256 Sep-84 R.KPVLKPNKPLILANR.V "sp|Q96BP2|CHCH1_HUMAN,tr|A6NJX6|A6NJX6_HUMAN" 2 1700.0825 1.22 130180 10342 4 1700.087099 426.0279 Coiled-coil-helix-coiled-coil-helix domain-containing protein 1 OS=Homo sapiens OX=9606 GN=CHCHD1 PE=1 SV=1 11.26 2162 - 290497 - - - 2.7081 - 1.492 0.411 - 54.1 1 2 0 0.0046 15 0 0 0 9.60E+07 7.89E+07 - - - 2.9452 1 221125_WJC_METTL3_EV_vs_WT_F09.10343.10343.4 1.07E-06 Oct-84 R.K[136.11]PVLK[136.11]PNK[136.11]PLILANR[166.11].V "sp|Q96BP2|CHCH1_HUMAN,tr|A6NJX6|A6NJX6_HUMAN" 2 1734.1334 1.22 130181 10343 4 1734.138324 434.5406 Coiled-coil-helix-coiled-coil-helix domain-containing protein 1 OS=Homo sapiens OX=9606 GN=CHCHD1 PE=1 SV=1 11.26 2162.2 - 275943 - - - 2.8596 - 2.319 0.625 - 110.7 1 2 0 0.005 15 0 0 0 9.60E+07 7.89E+07 - - - 4.9656 0.9999 221125_WJC_METTL3_EV_vs_WT_F09.10344.10344.3 2.95E-08 14/64 R.ATSLGR[166.11]PEEEEDELAHR[166.11].C "sp|P36551|HEM6_HUMAN,tr|D6RER6|D6RER6_HUMAN" 2 1957.9244 1.83 130182 10344 3 1957.928454 653.6488 "Oxygen-dependent coproporphyrinogen-III oxidase, mitochondrial OS=Homo sapiens OX=9606 GN=CPOX PE=1 SV=3" 4.41 2162.3 - 247175 - - - 2.0512 - 2.34 0.516 - 220.5 1 2 0 0.004 17 0 0 0 1.13E+07 6.17E+06 - - - 6.4395 0.9989 221125_WJC_METTL3_EV_vs_WT_F09.10345.10345.3 0.000119 Dec-64 K.VAAEVPHGSKQELQDLK.A "tr|A0A669KBG4|A0A669KBG4_HUMAN,tr|A0A669KAV7|A0A669KAV7_HUMAN,tr|M0QXA7|M0QXA7_HUMAN,tr|A0A669KBH9|A0A669KBH9_HUMAN,tr|B9EGQ5|B9EGQ5_HUMAN" 5 1847.9741 0.84 130183 10345 3 1847.98013 616.9987 Protein Wiz OS=Homo sapiens OX=9606 GN=WIZ PE=1 SV=1 5.44 2162.4 - 196524 - - - 3.2484 - 2.771 0.43 - 178.6 1 2 1 0.006 17 0 0 0 3.59E+06 4.28E+06 - - - 5.9072 0.9999 221125_WJC_METTL3_EV_vs_WT_F09.10347.10347.4 1.58E-05 12/102 K.EEAIEHNYGGHDDDLSVR.H "sp|Q93009|UBP7_HUMAN,tr|A0A669KBL1|A0A669KBL1_HUMAN,tr|F5H2X1|F5H2X1_HUMAN,tr|H3BND8|H3BND8_HUMAN" 4 2054.893 1.14 130185 10347 4 2054.899992 514.7305 Ubiquitin carboxyl-terminal hydrolase 7 OS=Homo sapiens OX=9606 GN=USP7 PE=1 SV=2 4.29 2162.7 - 135979 - - - 3.4143 - 2.912 0.568 - 153.3 1 2 0 0.007 18 0 0 0 2.86E+06 2.50E+06 - - - 4.5341 0.9994 221125_WJC_METTL3_EV_vs_WT_F09.10353.10353.2 1.44E-05 28-Jul K.HGSYEDAVHSGALND.- "sp|P17987|TCPA_HUMAN,tr|F5H282|F5H282_HUMAN,tr|E7EQR6|E7EQR6_HUMAN" 3 1570.6648 - 130189 10353 2 1570.668452 786.3397 T-complex protein 1 subunit alpha OS=Homo sapiens OX=9606 GN=TCP1 PE=1 SV=1 4.72 2163.5 - 182359 - - - 2.3162 - 1.328 0.573 - 76.7 1 2 0 0.0036 15 0 0 0 - - - - - 3.9695 0.9934 221125_WJC_METTL3_EV_vs_WT_F09.10355.10355.4 0.0395 Aug-72 R.DLLHPSLEEEK[136.11]K[136.11]K[136.11].H "sp|Q71UM5|RS27L_HUMAN,tr|H0YMV8|H0YMV8_HUMAN,tr|C9JLI6|C9JLI6_HUMAN" 3 1588.8887 0.54 130191 10355 4 1588.893792 398.2294 40S ribosomal protein S27-like OS=Homo sapiens OX=9606 GN=RPS27L PE=1 SV=3 5.53 2163.8 - 143921 - - - 3.2217 - 1.599 0.345 - 18 1 2 1 0.0051 13 0 0 0 9.35E+06 1.72E+07 - - - 2.4015 0.9975 221125_WJC_METTL3_EV_vs_WT_F09.10368.10368.3 0.000635 Sep-60 K.NLPLADQGSSHHITVK.L sp|P15924|DESP_HUMAN 1 1715.8955 27.6 130198 10368 3 1715.901398 572.9724 Desmoplakin OS=Homo sapiens OX=9606 GN=DSP PE=1 SV=3 6.92 2165.7 - 199415 - - - 3.4478 - 1.699 0.355 - 49.6 1 2 0 0.0059 16 0 0 0 8.96E+06 3.25E+05 - - - 3.8563 0.9581 221125_WJC_METTL3_EV_vs_WT_F09.10371.10371.3 0.0183 May-68 K.RNTNSVPETAPAAIPETK.R "sp|P55265|DSRAD_HUMAN,tr|A0A3B3ITG9|A0A3B3ITG9_HUMAN,tr|A0A3B3IRQ9|A0A3B3IRQ9_HUMAN,tr|A0A3B3ISU1|A0A3B3ISU1_HUMAN,tr|A0A7P0Z4K3|A0A7P0Z4K3_HUMAN,tr|A0A7P0TA14|A0A7P0TA14_HUMAN,tr|A0A3B3ISX1|A0A3B3ISX1_HUMAN,tr|A0A7P0Z4F9|A0A7P0Z4F9_HUMAN" 8 1894.9749 0.98 130201 10371 3 1894.980925 632.6656 Double-stranded RNA-specific adenosine deaminase OS=Homo sapiens OX=9606 GN=ADAR PE=1 SV=4 6.14 2166.1 - 83504 - - - 3.2032 - 1.309 0.247 - 22.3 2 2 0 0.0061 18 0 0 0 1.92E+06 1.96E+06 - - - 1.8233 1 221125_WJC_METTL3_EV_vs_WT_F09.10375.10375.3 2.12E-06 16/56 R.K[136.11]PVLK[136.11]PNK[136.11]PLILANR[166.11].V "sp|Q96BP2|CHCH1_HUMAN,tr|A6NJX6|A6NJX6_HUMAN" 2 1734.1334 1.35 130203 10375 3 1734.13755 579.0517 Coiled-coil-helix-coiled-coil-helix domain-containing protein 1 OS=Homo sapiens OX=9606 GN=CHCHD1 PE=1 SV=1 11.26 2166.6 - 368029 - - - 2.4133 - 2.805 0.75 - 276.4 1 2 0 0.0042 15 0 0 0 2.37E+07 1.76E+07 - - - 9.5919 0.9967 221125_WJC_METTL3_EV_vs_WT_F09.10380.10380.3 0.0331 Jun-44 K.GISVHISNAEPK.H "sp|Q13148|TADBP_HUMAN,tr|A0A087WX67|A0A087WX67_HUMAN,tr|A0A087WX29|A0A087WX29_HUMAN,tr|G3V162|G3V162_HUMAN,tr|A0A087WV68|A0A087WV68_HUMAN,tr|A0A087WXV3|A0A087WXV3_HUMAN,tr|A0A087WYY0|A0A087WYY0_HUMAN,tr|A0A087WTZ4|A0A087WTZ4_HUMAN,tr|A0A087WW61|A0A087WW61_HUMAN,tr|A0A087WYE7|A0A087WYE7_HUMAN,tr|B1AKP7|B1AKP7_HUMAN,tr|K7EL26|K7EL26_HUMAN,tr|A0A087WZC9|A0A087WZC9_HUMAN,tr|A0A087WXQ5|A0A087WXQ5_HUMAN,tr|A0A087X260|A0A087X260_HUMAN" 15 1250.6619 1 130206 10380 3 1250.664298 417.8946 TAR DNA-binding protein 43 OS=Homo sapiens OX=9606 GN=TARDBP PE=1 SV=1 6.75 2167.4 - 150363 - - - 1.9174 - 1.245 0.349 - 32.6 2 2 0 0.0024 12 0 0 0 2.09E+06 2.10E+06 - - - 2.8984 0.9777 221125_WJC_METTL3_EV_vs_WT_F09.10382.10382.3 0.0149 Oct-60 K.KAVDQHNAEAQDIFGK.N "sp|P52732|KIF11_HUMAN,tr|A0A7I2YQY4|A0A7I2YQY4_HUMAN,tr|A0A7I2V3A9|A0A7I2V3A9_HUMAN" 3 1769.8697 3.42 130208 10382 3 1769.875925 590.9638 Kinesin-like protein KIF11 OS=Homo sapiens OX=9606 GN=KIF11 PE=1 SV=2 5.38 2167.6 - 581951 - - - 3.5387 - 1.672 0.226 - 67.6 1 2 0 0.0063 16 0 0 0 2.00E+07 5.84E+06 - - - 2.3768 1 221125_WJC_METTL3_EV_vs_WT_F09.10399.10399.3 1.18E-05 13/68 R.VNPHSLPDPEVNEQSSSK.G "sp|Q99575|POP1_HUMAN,tr|E5RK39|E5RK39_HUMAN" 2 1962.9283 1.21 130221 10399 3 1962.932186 655.3167 Ribonucleases P\MRP protein subunit POP1 OS=Homo sapiens OX=9606 GN=POP1 PE=1 SV=2 4.65 2169.8 - 161115 - - - 1.9802 - 2.629 0.553 - 175.1 1 2 0 0.0039 18 0 0 0 5.73E+06 4.72E+06 - - - 7.1113 0.9986 221125_WJC_METTL3_EV_vs_WT_F09.10404.10404.4 0.00411 9/102 K.AAPAQVRPPSPGNIRPVK.R "sp|Q14244|MAP7_HUMAN,tr|A0A087WZ40|A0A087WZ40_HUMAN" 2 1854.0588 1.27 130224 10404 4 1854.065156 464.522 Ensconsin OS=Homo sapiens OX=9606 GN=MAP7 PE=1 SV=1 12.01 2170.6 - 278263 - - - 3.4282 - 1.905 0.356 - 48.6 1 2 0 0.0064 18 0 0 0 8.35E+06 6.60E+06 - - - 2.5436 0.9144 221125_WJC_METTL3_EV_vs_WT_F09.10405.10405.3 3.98E-06 Nov-68 R.RLLEGEDAHLSSQQASGQ.S sp|P08779|K1C16_HUMAN 1 1924.9239 999 130225 10405 3 1924.93003 642.6486 "Keratin, type I cytoskeletal 16 OS=Homo sapiens OX=9606 GN=KRT16 PE=1 SV=4" 4.65 2170.7 - 103855 - - - 3.1939 - 2.428 0.342 - 187.2 1 1 0 0.0061 18 0 0 0 4.93E+06 0.00E+00 - - - 4.5601 0.9994 221125_WJC_METTL3_EV_vs_WT_F09.10406.10406.3 0.000129 Nov-48 R.DLLHPSLEEEKKK.H "sp|Q71UM5|RS27L_HUMAN,tr|H0YMV8|H0YMV8_HUMAN,tr|C9JLI6|C9JLI6_HUMAN" 3 1564.8461 0.49 130226 10406 3 1564.851465 522.6226 40S ribosomal protein S27-like OS=Homo sapiens OX=9606 GN=RPS27L PE=1 SV=3 5.53 2170.8 - 229743 - - - 3.4457 - 2.285 0.528 - 132.2 1 2 1 0.0054 13 0 0 0 5.07E+06 1.03E+07 - - - 6.6657 0.781 221125_WJC_METTL3_EV_vs_WT_F09.10408.10408.4 0.0346 9/114 K.LEVQATDR[166.11]EENK[136.11]QIALGTSK[136.11].L "sp|P11387|TOP1_HUMAN,tr|A0A7P0T852|A0A7P0T852_HUMAN" 2 2255.1968 0.28 130228 10408 4 2255.204886 564.8065 DNA topoisomerase 1 OS=Homo sapiens OX=9606 GN=TOP1 PE=1 SV=2 4.87 2171.1 - 142647 - - - 3.6032 - 1.636 0.19 - 52 1 2 2 0.0081 20 0 0 0 6.01E+05 2.13E+06 - - - 1.0421 0.9996 221125_WJC_METTL3_EV_vs_WT_F09.10410.10410.3 0.000699 Jul-92 K.APPTLQAETATK[136.11]PQATSAPSPAPK[136.11].Q "sp|Q96HA1|P121A_HUMAN,sp|A8CG34|P121C_HUMAN" 2 2375.2667 1.97 130230 10410 3 2375.268761 792.7629 Nuclear envelope pore membrane protein POM 121 OS=Homo sapiens OX=9606 GN=POM121 PE=1 SV=2 8.64 2171.4 - 46640.4 - - - 0.8509 - 1.474 0.413 - 36.7 1 2 0 0.002 24 0 0 0 6.43E+07 3.26E+07 - - - 4.0451 0.9999 221125_WJC_METTL3_EV_vs_WT_F09.10415.10415.3 0.000122 Nov-68 R.ETVAVK[136.11]PTENNEEEFTSK[136.11].D "sp|O60841|IF2P_HUMAN,tr|A0A087WUT6|A0A087WUT6_HUMAN" 2 2066.9979 0.79 130233 10415 3 2067.002876 690.0066 Eukaryotic translation initiation factor 5B OS=Homo sapiens OX=9606 GN=EIF5B PE=1 SV=4 4.33 2172.1 - 124743 - - - 2.4098 - 2.39 0.564 - 154.3 1 2 0 0.005 18 0 0 0 6.62E+06 8.40E+06 - - - 6.9963 1 221125_WJC_METTL3_EV_vs_WT_F09.10418.10418.3 7.67E-10 14/92 K.APPTLQAETATKPQATSAPSPAPK.Q "sp|Q96HA1|P121A_HUMAN,sp|A8CG34|P121C_HUMAN" 2 2359.2383 1.97 130236 10418 3 2359.243209 787.4201 Nuclear envelope pore membrane protein POM 121 OS=Homo sapiens OX=9606 GN=POM121 PE=1 SV=2 8.64 2172.5 - 136361 - - - 2.0638 - 3.487 0.65 - 151.7 1 2 0 0.0049 24 0 0 0 6.43E+07 3.26E+07 - - - 8.6865 0.9992 221125_WJC_METTL3_EV_vs_WT_F09.10423.10423.3 0.00261 Aug-68 R.ETVAVKPTENNEEEFTSK.D "sp|O60841|IF2P_HUMAN,tr|A0A087WUT6|A0A087WUT6_HUMAN" 2 2050.9695 0.79 130239 10423 3 2050.97544 684.6638 Eukaryotic translation initiation factor 5B OS=Homo sapiens OX=9606 GN=EIF5B PE=1 SV=4 4.33 2173.1 - 165559 - - - 2.8986 - 1.843 0.398 - 68 1 2 0 0.0059 18 0 0 0 6.62E+06 8.40E+06 - - - 4.4981 0.9926 221125_WJC_METTL3_EV_vs_WT_F09.10425.10425.3 0.00654 Aug-48 K.NPSDSAVHSPFTK[136.11].R "sp|Q14157|UBP2L_HUMAN,tr|F8W726|F8W726_HUMAN" 2 1393.6717 3.48 130241 10425 3 1393.673897 465.5645 Ubiquitin-associated protein 2-like OS=Homo sapiens OX=9606 GN=UBAP2L PE=1 SV=2 6.74 2173.4 - 163892 - - - 1.5456 - 1.413 0.247 - 62 1 2 0 0.0022 13 0 0 0 8.82E+06 2.53E+06 - - - 2.2305 0.9977 221125_WJC_METTL3_EV_vs_WT_F09.10445.10445.3 0.00653 Aug-60 K.NLTEQNSYSNIPHEGK.H "sp|Q5T035|CI129_HUMAN,sp|Q9NZB2|F120A_HUMAN,tr|A0A0C4DH52|A0A0C4DH52_HUMAN" 3 1829.8544 0.59 130257 10445 3 1829.858159 610.9587 Putative uncharacterized protein C9orf129 OS=Homo sapiens OX=9606 GN=C9orf129 PE=4 SV=1 5.4 2176.1 - 226417 - - - 2.0515 - 1.453 0.332 - 53.1 1 2 0 0.0038 16 0 0 0 3.60E+06 6.11E+06 - - - 3.1991 0.9999 221125_WJC_METTL3_EV_vs_WT_F09.10446.10446.4 0.00125 11/102 R.TQDALQQRPSVLHNTGMK.G "sp|Q9Y618|NCOR2_HUMAN,tr|C9J7T7|C9J7T7_HUMAN,tr|C9JE98|C9JE98_HUMAN,tr|H7C1J7|H7C1J7_HUMAN,tr|C9J0Q5|C9J0Q5_HUMAN,tr|H7C0P3|H7C0P3_HUMAN,tr|A0A384DVL6|A0A384DVL6_HUMAN" 7 2023.0269 1.5 130258 10446 4 2023.030853 506.764 Nuclear receptor corepressor 2 OS=Homo sapiens OX=9606 GN=NCOR2 PE=1 SV=3 8.44 2176.2 - 246385 - - - 1.9505 - 1.974 0.436 - 81.7 1 2 0 0.0039 18 0 0 0 3.32E+06 2.21E+06 - - - 3.2528 0.9997 221125_WJC_METTL3_EV_vs_WT_F09.10453.10453.3 0.00283 Aug-60 K.STAGDTHLGGEDFDNR.M "sp|P54652|HSP72_HUMAN,sp|P11142|HSP7C_HUMAN,tr|E9PKE3|E9PKE3_HUMAN,tr|E9PN89|E9PN89_HUMAN" 4 1690.7183 0.16 130263 10453 3 1690.720481 564.58 Heat shock-related 70 kDa protein 2 OS=Homo sapiens OX=9606 GN=HSPA2 PE=1 SV=1 4.22 2177.2 - 103199 - - - 1.2864 - 1.635 0.424 - 80.5 1 2 0 0.0022 16 0 0 0 7.07E+06 4.38E+07 - - - 4.5281 0.9996 221125_WJC_METTL3_EV_vs_WT_F09.10454.10454.3 0.00052 Oct-40 K.TPVEPEVAIHR.L "sp|P60866|RS20_HUMAN,tr|E5RJX2|E5RJX2_HUMAN,tr|E5RIP1|E5RIP1_HUMAN,tr|A0A7P0S5H5|A0A7P0S5H5_HUMAN" 4 1246.667 1.23 130264 10454 3 1246.670156 416.5629 40S ribosomal protein S20 OS=Homo sapiens OX=9606 GN=RPS20 PE=1 SV=1 5.37 2177.3 - 70198.9 - - - 2.5428 - 2.036 0.393 - 206.2 1 2 0 0.0032 11 0 0 0 5.52E+06 4.48E+06 - - - 4.9405 0.9999 221125_WJC_METTL3_EV_vs_WT_F09.10459.10459.4 1.04E-10 21/138 K.APPTLQAETATKPQATSAPSPAPK.Q "sp|Q96HA1|P121A_HUMAN,sp|A8CG34|P121C_HUMAN" 2 2359.2383 2.01 130267 10459 4 2359.246741 590.8169 Nuclear envelope pore membrane protein POM 121 OS=Homo sapiens OX=9606 GN=POM121 PE=1 SV=2 8.64 2178 - 322152 - - - 3.5609 - 3.919 0.601 - 301.3 1 2 0 0.0084 24 0 0 0 9.24E+06 4.59E+06 - - - 4.8932 0.9998 221125_WJC_METTL3_EV_vs_WT_F09.10464.10464.3 0.000203 Dec-40 K.TPVEPEVAIHR[166.11].L "sp|P60866|RS20_HUMAN,tr|E5RJX2|E5RJX2_HUMAN,tr|E5RIP1|E5RIP1_HUMAN,tr|A0A7P0S5H5|A0A7P0S5H5_HUMAN" 4 1256.6753 1.27 130270 10464 3 1256.678915 419.899 40S ribosomal protein S20 OS=Homo sapiens OX=9606 GN=RPS20 PE=1 SV=1 5.37 2178.7 - 134812 - - - 2.9117 - 2.332 0.426 - 247.9 1 2 0 0.0037 11 0 0 0 5.49E+06 4.31E+06 - - - 5.6939 0.9999 221125_WJC_METTL3_EV_vs_WT_F09.10465.10465.4 7.96E-07 13/138 K.APPTLQAETATK[136.11]PQATSAPSPAPK[136.11].Q "sp|Q96HA1|P121A_HUMAN,sp|A8CG34|P121C_HUMAN" 2 2375.2667 2.01 130271 10465 4 2375.273567 594.824 Nuclear envelope pore membrane protein POM 121 OS=Homo sapiens OX=9606 GN=POM121 PE=1 SV=2 8.64 2178.8 - 198539 - - - 2.8742 - 2.833 0.527 - 94.2 1 2 0 0.0068 24 0 0 0 9.24E+06 4.59E+06 - - - 4.1454 0.9999 221125_WJC_METTL3_EV_vs_WT_F09.10466.10466.3 8.06E-05 Sep-60 K.ATAGDTHLGGEDFDNR[166.11].L "sp|P48741|HSP77_HUMAN,sp|P0DMV8|HS71A_HUMAN,sp|P34931|HS71L_HUMAN,sp|P0DMV9|HS71B_HUMAN,sp|P17066|HSP76_HUMAN,tr|Q53FA3|Q53FA3_HUMAN,tr|V9GZ37|V9GZ37_HUMAN,tr|A0A0G2JIW1|A0A0G2JIW1_HUMAN" 8 1684.7317 0.05 130272 10466 3 1684.735031 562.5845 Putative heat shock 70 kDa protein 7 OS=Homo sapiens OX=9606 GN=HSPA7 PE=5 SV=2 4.22 2179 - 165338 - - - 2.0003 - 1.932 0.468 - 77.3 1 2 0 0.0034 16 0 0 0 2.74E+05 5.35E+06 - - - 5.4466 0.9912 221125_WJC_METTL3_EV_vs_WT_F09.10470.10470.2 7.21E-06 Aug-36 R.SDSPVPTAPTSGGPK[136.11]PSTA.S "sp|Q86U44|MTA70_HUMAN,tr|B4E349|B4E349_HUMAN,tr|F5H6D8|F5H6D8_HUMAN,tr|B4DTN4|B4DTN4_HUMAN" 4 1760.8672 0.02 130276 10470 2 1760.866656 881.4409 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 5.55 2179.5 - 37453.8 - - - -0.3135 - 1.653 0.574 - 114.5 1 1 0 -0.0006 19 0 0 0 3.65E+05 2.39E+07 - - - 4.516 0.987 221125_WJC_METTL3_EV_vs_WT_F09.10474.10474.3 0.00117 Sep-64 M.SVEVDGNSFEASGPSKK.T sp|Q12906|ILF3_HUMAN 1 1736.8217 1.3 130278 10474 3 1736.823829 579.9478 Interleukin enhancer-binding factor 3 OS=Homo sapiens OX=9606 GN=ILF3 PE=1 SV=3 4.68 2180 - 275504 - - - 1.2212 - 1.87 0.454 - 48.4 1 1 0 0.0021 17 0 0 0 8.45E+06 6.50E+06 - - - 5.1824 0.9983 221125_WJC_METTL3_EV_vs_WT_F09.10476.10476.3 1.99E-08 Dec-56 Q.DDAHPTLVTYADHSK[136.11].L "sp|Q86U44|MTA70_HUMAN,tr|F5H6D8|F5H6D8_HUMAN,tr|H0YFV6|H0YFV6_HUMAN,tr|B4DTN4|B4DTN4_HUMAN" 4 1676.7886 0.12 130280 10476 3 1676.790226 559.9368 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 5.13 2180.3 - 263733 - - - 0.9912 - 2.472 0.6 - 216.2 1 1 0 0.0017 15 0 0 0 1.41E+06 1.17E+07 - - - 7.5905 1 221125_WJC_METTL3_EV_vs_WT_F09.10485.10485.3 7.63E-08 15/60 K.STAGDTHLGGEDFDNR[166.11].M "sp|P54652|HSP72_HUMAN,sp|P11142|HSP7C_HUMAN,tr|E9PKE3|E9PKE3_HUMAN,tr|E9PN89|E9PN89_HUMAN" 4 1700.7266 0.17 130286 10485 3 1700.728433 567.9161 Heat shock-related 70 kDa protein 2 OS=Homo sapiens OX=9606 GN=HSPA2 PE=1 SV=1 4.22 2181.5 - 1.10E+06 - - - 1.0919 - 2.631 0.573 - 291.8 1 2 0 0.0019 16 0 0 0 5.71E+06 3.45E+07 - - - 7.41 0.9968 221125_WJC_METTL3_EV_vs_WT_F09.10487.10487.3 9.52E-06 14/64 M.SVEVDGNSFEASGPSK[136.11]K[136.11].T sp|Q12906|ILF3_HUMAN 1 1752.8501 1.3 130287 10487 3 1752.847238 585.2906 Interleukin enhancer-binding factor 3 OS=Homo sapiens OX=9606 GN=ILF3 PE=1 SV=3 4.68 2181.7 - 409061 - - - -1.6373 - 2.663 0.534 - 137.5 1 1 0 -0.0029 17 0 0 0 8.45E+06 6.50E+06 - - - 6.9672 0.9999 221125_WJC_METTL3_EV_vs_WT_F09.10489.10489.3 1.87E-05 Oct-56 K.VHPEIINENGNPSYK[136.11].Y sp|O95881|TXD12_HUMAN 1 1717.8515 1.29 130289 10489 3 1717.853881 573.6244 Thioredoxin domain-containing protein 12 OS=Homo sapiens OX=9606 GN=TXNDC12 PE=1 SV=1 5.4 2182 - 143463 - - - 1.3866 - 2.061 0.501 - 120.3 1 2 0 0.0024 15 0 0 0 5.01E+06 3.88E+06 - - - 6.0121 0.96 221125_WJC_METTL3_EV_vs_WT_F09.10496.10496.4 0.000189 Dec-84 Q.DDAHPTLVTYADHSK[136.11].L "sp|Q86U44|MTA70_HUMAN,tr|F5H6D8|F5H6D8_HUMAN,tr|H0YFV6|H0YFV6_HUMAN,tr|B4DTN4|B4DTN4_HUMAN" 4 1676.7886 0.07 130293 10496 4 1676.788765 420.2044 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 5.13 2182.9 - 463668 - - - 0.1199 - 1.908 0.353 - 110.2 1 1 0 0.0002 15 0 0 0 6.60E+05 9.16E+06 - - - 2.5296 0.9996 221125_WJC_METTL3_EV_vs_WT_F09.10498.10498.3 0.00614 Jun-80 K.EGGVPLAPNQPVHGTQADQER[166.11].L "sp|O75143|ATG13_HUMAN,tr|H0YEM7|H0YEM7_HUMAN" 2 2209.0751 1.69 130295 10498 3 2209.075733 737.3657 Autophagy-related protein 13 OS=Homo sapiens OX=9606 GN=ATG13 PE=1 SV=1 4.65 2183.1 - 71214.8 - - - 0.2739 - 1.674 0.371 - 30.7 1 2 0 0.0006 21 0 0 0 1.51E+06 8.95E+05 - - - 3.9113 0.9997 221125_WJC_METTL3_EV_vs_WT_F09.10502.10502.3 0.000737 Oct-56 K.VHPEIINENGNPSYK.Y sp|O95881|TXD12_HUMAN 1 1709.8373 1.29 130297 10502 3 1709.839345 570.953 Thioredoxin domain-containing protein 12 OS=Homo sapiens OX=9606 GN=TXNDC12 PE=1 SV=1 5.4 2183.6 - 261322 - - - 1.1966 - 2.093 0.352 - 131.5 1 2 0 0.002 15 0 0 0 5.02E+06 3.88E+06 - - - 4.3912 1 221125_WJC_METTL3_EV_vs_WT_F09.10504.10504.3 3.04E-05 Nov-68 R.NTNSVPETAPAAIPETK[136.11]R[166.11].N "sp|P55265|DSRAD_HUMAN,tr|A0A3B3ITG9|A0A3B3ITG9_HUMAN,tr|A0A3B3IRQ9|A0A3B3IRQ9_HUMAN,tr|A0A3B3ISU1|A0A3B3ISU1_HUMAN,tr|A0A7P0Z4K3|A0A7P0Z4K3_HUMAN,tr|A0A7P0TA14|A0A7P0TA14_HUMAN,tr|A0A3B3ISX1|A0A3B3ISX1_HUMAN,tr|A0A7P0Z4F9|A0A7P0Z4F9_HUMAN" 8 1912.9973 0.87 130299 10504 3 1912.994775 638.6731 Double-stranded RNA-specific adenosine deaminase OS=Homo sapiens OX=9606 GN=ADAR PE=1 SV=4 6.14 2183.9 - 138407 - - - -1.333 - 2.417 0.499 - 95.5 1 2 0 -0.0026 18 0 0 0 9.47E+06 1.09E+07 - - - 6.3002 1 221125_WJC_METTL3_EV_vs_WT_F09.10518.10518.3 5.04E-07 Oct-56 K.VHPEIINENGNPSYK[136.11].Y sp|O95881|TXD12_HUMAN 1 1717.8515 1.29 130309 10518 3 1717.850929 573.6244 Thioredoxin domain-containing protein 12 OS=Homo sapiens OX=9606 GN=TXNDC12 PE=1 SV=1 5.4 2185.8 - 226320 - - - -0.3318 - 2.443 0.57 - 163.3 1 2 0 -0.0006 15 0 0 0 5.01E+06 3.88E+06 - - - 7.2255 1 221125_WJC_METTL3_EV_vs_WT_F09.10519.10519.3 5.37E-06 Nov-44 R.KQEELQQLEQQR.R "sp|Q15149|PLEC_HUMAN,tr|H0YDN1|H0YDN1_HUMAN" 2 1555.7954 1.11 130310 10519 3 1555.796894 519.6058 Plectin OS=Homo sapiens OX=9606 GN=PLEC PE=1 SV=3 4.79 2185.9 - 307524 - - - 0.9384 - 2.431 0.515 - 161.4 1 2 0 0.0015 12 0 0 0 5.02E+06 4.51E+06 - - - 6.7436 0.9559 221125_WJC_METTL3_EV_vs_WT_F09.10520.10520.4 0.128 Aug-96 K.WLPVQESSTDDK[136.11]K[136.11]PGER[166.11].K "sp|Q9Y6A9|SPCS1_HUMAN,tr|A0A5F9YFS9|A0A5F9YFS9_HUMAN,tr|C9JBL1|C9JBL1_HUMAN" 3 1997.0064 0.56 130311 10520 4 1997.006077 500.2589 Signal peptidase complex subunit 1 OS=Homo sapiens OX=9606 GN=SPCS1 PE=1 SV=5 4.78 2186 - 205140 - - - -0.1818 - 1.338 0.206 - 38.7 1 2 1 -0.0004 17 0 0 0 2.67E+06 4.74E+06 - - - 1.12 0.9973 221125_WJC_METTL3_EV_vs_WT_F09.10521.10521.4 0.123 Nov-96 K.WLPVQESSTDDKKPGER.K "sp|Q9Y6A9|SPCS1_HUMAN,tr|A0A5F9YFS9|A0A5F9YFS9_HUMAN,tr|C9JBL1|C9JBL1_HUMAN" 3 1970.9698 0.57 130312 10521 4 1970.973214 493.7497 Signal peptidase complex subunit 1 OS=Homo sapiens OX=9606 GN=SPCS1 PE=1 SV=5 4.78 2186.2 - 177776 - - - 1.7474 - 1.554 0.342 - 55.1 1 2 1 0.0034 17 0 0 0 2.66E+06 4.68E+06 - - - 2.3549 0.9919 221125_WJC_METTL3_EV_vs_WT_F09.10526.10526.4 999 Feb-96 W.YC[160.03]DGDTDC[160.03]KDGSDEENC[160.03].- tr|E9PNJ5|E9PNJ5_HUMAN 1 2038.6463 11.57 130315 10526 4 2038.646356 510.6688 Low-density lipoprotein receptor-related protein 4 (Fragment) OS=Homo sapiens OX=9606 GN=LRP4 PE=1 SV=1 3.57 2186.9 - 358629 - - - 0.0446 - 0.257 0.673 - 1.3 1 1 1 0.0001 17 0 0 0 1.92E+07 1.66E+06 - - - 4.612 1 221125_WJC_METTL3_EV_vs_WT_F09.10527.10527.3 0.206 17/68 R.TPAPEPEPC[160.03]EASELPAKR.L "sp|Q9ULV3|CIZ1_HUMAN,tr|Q5SYW2|Q5SYW2_HUMAN,tr|F5H2X7|F5H2X7_HUMAN,tr|H0Y5D5|H0Y5D5_HUMAN,tr|A0A494C0L7|A0A494C0L7_HUMAN,tr|Q9BTG3|Q9BTG3_HUMAN" 6 1977.9466 5.2 130316 10527 3 1977.949811 660.3228 Cip1-interacting zinc finger protein OS=Homo sapiens OX=9606 GN=CIZ1 PE=1 SV=2 4.49 2187 - 360063 - - - 1.6274 - 3.354 0.504 - 376.3 1 2 0 0.0032 18 0 0 0 7.15E+06 1.38E+06 - - - 7.1716 0.9407 221125_WJC_METTL3_EV_vs_WT_F09.10540.10540.2 1.68 16-Jun K.DLPEHAVLK[136.11].M "sp|Q00839|HNRPU_HUMAN,tr|A0A1W2PQL0|A0A1W2PQL0_HUMAN,tr|A0A1W2PPL4|A0A1W2PPL4_HUMAN,tr|A0A1W2PQ74|A0A1W2PQ74_HUMAN,tr|Q5RI18|Q5RI18_HUMAN,tr|A0A1W2PP35|A0A1W2PP35_HUMAN,tr|A0A1W2PPS1|A0A1W2PPS1_HUMAN,tr|A0A1W2PRZ7|A0A1W2PRZ7_HUMAN,tr|A0A1W2PPH7|A0A1W2PPH7_HUMAN,tr|A0A1W2PQD4|A0A1W2PQD4_HUMAN,tr|A0A1W2PP34|A0A1W2PP34_HUMAN,tr|A0A1X7SBS1|A0A1X7SBS1_HUMAN" 12 1028.5746 1.23 130327 10540 2 1028.577633 515.2946 Heterogeneous nuclear ribonucleoprotein U OS=Homo sapiens OX=9606 GN=HNRNPU PE=1 SV=6 5.32 2188.6 - 157127 - - - 2.9536 - 1.092 0.149 - 105.3 1 2 0 0.003 9 0 0 0 2.95E+06 2.41E+06 - - - 0.3952 0.9996 221125_WJC_METTL3_EV_vs_WT_F09.10541.10541.3 6.24E-06 Nov-72 K.GNEKEDAAGTSGLGELNSR.E "sp|Q5T3I0|GPTC4_HUMAN,tr|F8W895|F8W895_HUMAN,tr|A0A0A0MRK1|A0A0A0MRK1_HUMAN,tr|E9PAV9|E9PAV9_HUMAN" 4 1903.8872 1.36 130328 10541 3 1903.891764 635.6363 G patch domain-containing protein 4 OS=Homo sapiens OX=9606 GN=GPATCH4 PE=1 SV=2 4.41 2188.8 - 153749 - - - 2.4172 - 1.979 0.564 - 100.3 1 2 1 0.0046 19 0 0 0 4.55E+06 3.34E+06 - - - 6.5038 0.9999 221125_WJC_METTL3_EV_vs_WT_F09.10542.10542.3 7.25E-07 Dec-68 R.ESGSSTAEEGDFSKGPIR.C "sp|Q13127|REST_HUMAN,tr|A0A1W2PQA1|A0A1W2PQA1_HUMAN,tr|L0B1V4|L0B1V4_HUMAN,tr|L0B3M6|L0B3M6_HUMAN,tr|A0A087X1C2|A0A087X1C2_HUMAN,tr|L0B2V9|L0B2V9_HUMAN" 6 1852.8439 3.84 130329 10542 3 1852.847174 618.6219 RE1-silencing transcription factor OS=Homo sapiens OX=9606 GN=REST PE=1 SV=3 4.41 2188.9 - 153012 - - - 1.767 - 2.624 0.594 - 136.4 1 2 1 0.0033 18 0 0 0 2.63E+06 6.84E+05 - - - 7.5638 0.9999 221125_WJC_METTL3_EV_vs_WT_F09.10550.10550.3 1.59E-07 13/52 R.K[136.11]NPLPPSVGVVDK[136.11]K[136.11].E sp|Q8NC51|PAIRB_HUMAN 1 1500.909 0.76 130335 10550 3 1500.912431 501.3103 Plasminogen activator inhibitor 1 RNA-binding protein OS=Homo sapiens OX=9606 GN=SERBP1 PE=1 SV=2 9.7 2190 - 136424 - - - 2.2766 - 2.623 0.457 - 208.4 1 2 0 0.0034 14 0 0 0 2.81E+06 3.69E+06 - - - 6.1969 0.9998 221125_WJC_METTL3_EV_vs_WT_F09.10551.10551.3 1.03E-07 14/72 K.GNEK[136.11]EDAAGTSGLGELNSR[166.11].E "sp|Q5T3I0|GPTC4_HUMAN,tr|F8W895|F8W895_HUMAN,tr|A0A0A0MRK1|A0A0A0MRK1_HUMAN,tr|E9PAV9|E9PAV9_HUMAN" 4 1921.9096 1.4 130336 10551 3 1921.913635 641.6438 G patch domain-containing protein 4 OS=Homo sapiens OX=9606 GN=GPATCH4 PE=1 SV=2 4.41 2190.1 - 170820 - - - 2.0828 - 2.442 0.571 - 180.1 1 2 1 0.004 19 0 0 0 4.55E+06 3.24E+06 - - - 7.0985 0.9927 221125_WJC_METTL3_EV_vs_WT_F09.10554.10554.3 0.00299 Jul-60 R.K[136.11]TC[160.03]TTVAFTQVNSEDK[136.11].G "sp|P62424|RL7A_HUMAN,tr|Q5T8U2|Q5T8U2_HUMAN" 2 1843.8957 0.001 130339 10554 3 1843.90248 615.6392 60S ribosomal protein L7a OS=Homo sapiens OX=9606 GN=RPL7A PE=1 SV=2 6.06 2190.5 - 105287 - - - 3.6884 - 1.572 0.315 - 69.8 1 2 0 0.0068 16 0 0 0 0.00E+00 1.35E+06 - - - 3.2107 0.9945 221125_WJC_METTL3_EV_vs_WT_F09.10555.10555.2 0.0769 Feb-36 K.GAEAANVTGPGGVPVQGSK[136.11].Y "sp|P67809|YBOX1_HUMAN,tr|H0Y449|H0Y449_HUMAN,tr|C9J5V9|C9J5V9_HUMAN" 3 1702.873 0.94 130340 10555 2 1702.873242 852.4438 Y-box-binding protein 1 OS=Homo sapiens OX=9606 GN=YBX1 PE=1 SV=3 6 2190.7 - 54859.5 - - - 0.1638 - 0.812 0.392 - 6.9 7 2 0 0.0003 19 0 0 0 1.37E+06 1.46E+06 - - - 1.0467 0.9999 221125_WJC_METTL3_EV_vs_WT_F09.10567.10567.4 5.93E-07 Dec-84 R.KPVLKPNKPLILANR.V "sp|Q96BP2|CHCH1_HUMAN,tr|A6NJX6|A6NJX6_HUMAN" 2 1700.0825 1.22 130348 10567 4 1700.088296 426.0279 Coiled-coil-helix-coiled-coil-helix domain-containing protein 1 OS=Homo sapiens OX=9606 GN=CHCHD1 PE=1 SV=1 11.26 2192.4 - 248796 - - - 3.4122 - 2.315 0.62 - 91.5 1 2 0 0.0058 15 0 0 0 9.76E+07 8.00E+07 - - - 4.9212 0.9992 221125_WJC_METTL3_EV_vs_WT_F09.10569.10569.2 0.000429 26-Sep K.SSGASVTTQPTEFK.L "sp|Q9BY77|PDIP3_HUMAN,tr|F6VRR5|F6VRR5_HUMAN" 2 1438.694 1.48 130350 10569 2 1438.698071 720.3543 Polymerase delta-interacting protein 3 OS=Homo sapiens OX=9606 GN=POLDIP3 PE=1 SV=2 5.72 2192.6 - 157395 - - - 2.8373 - 1.93 0.47 - 257.5 1 2 0 0.0041 14 0 0 0 1.82E+06 1.23E+06 - - - 4.1612 1 221125_WJC_METTL3_EV_vs_WT_F09.10570.10570.3 5.61E-08 13/76 R.GQVK[136.11]PSTSSQPILSAPGPTK[136.11].L "sp|Q9ULT8|HECD1_HUMAN,tr|G3V4V5|G3V4V5_HUMAN,tr|A0A087X2H1|A0A087X2H1_HUMAN,tr|H0YJP0|H0YJP0_HUMAN" 4 1995.0972 0.69 130351 10570 3 1995.101171 666.0397 E3 ubiquitin-protein ligase HECTD1 OS=Homo sapiens OX=9606 GN=HECTD1 PE=1 SV=3 10 2192.8 - 156328 - - - 2.0129 - 2.68 0.603 - 148.5 1 2 0 0.004 20 0 0 0 5.39E+06 7.81E+06 - - - 7.6534 0.9978 221125_WJC_METTL3_EV_vs_WT_F09.10572.10572.2 5.46E-05 26-Oct K.K[136.11]GPGEVAGTVTGQK[136.11].R "sp|Q86U44|MTA70_HUMAN,tr|F5H6D8|F5H6D8_HUMAN,tr|H0YFV6|H0YFV6_HUMAN,tr|B4DTN4|B4DTN4_HUMAN" 4 1343.738 0.83 130353 10572 2 1343.744952 672.8763 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 8.59 2193 - 79329.5 - - - 5.1893 - 2.059 0.601 - 266 1 2 0 0.007 14 0 0 0 1.41E+06 1.69E+06 - - - 5.2902 0.9871 221125_WJC_METTL3_EV_vs_WT_F09.10577.10577.3 0.021 Aug-84 K.AGGK[136.11]PSQSPSQEAAGEAVLGAK[136.11].T sp|P00519|ABL1_HUMAN 1 2055.0567 0.84 130356 10577 3 2055.065624 686.0262 Tyrosine-protein kinase ABL1 OS=Homo sapiens OX=9606 GN=ABL1 PE=1 SV=4 6.19 2193.6 - 82380.7 - - - 4.3196 - 1.709 0.298 - 55.2 1 2 0 0.0089 22 0 0 0 1.14E+06 1.35E+06 - - - 3.1305 0.9918 221125_WJC_METTL3_EV_vs_WT_F09.10582.10582.3 0.0739 Sep-56 R.NDTKEDVFVHQTAIK.R "sp|Q9Y2T7|YBOX2_HUMAN,sp|P67809|YBOX1_HUMAN,sp|P16989|YBOX3_HUMAN,tr|H0Y449|H0Y449_HUMAN,tr|A0A0D9SEI8|A0A0D9SEI8_HUMAN" 5 1743.8792 1.09 130359 10582 3 1743.885248 582.3003 Y-box-binding protein 2 OS=Homo sapiens OX=9606 GN=YBX2 PE=1 SV=2 5.38 2194.3 - 131394 - - - 3.4888 - 2.01 0.34 - 84.6 1 2 1 0.0061 15 0 0 0 8.41E+07 7.74E+07 - - - 4.1507 0.999 221125_WJC_METTL3_EV_vs_WT_F09.10585.10585.3 0.000914 Nov-44 R.QTVEADVNGLRR.V sp|P08779|K1C16_HUMAN 1 1356.711 6.39 130360 10585 3 1356.714499 453.2443 "Keratin, type I cytoskeletal 16 OS=Homo sapiens OX=9606 GN=KRT16 PE=1 SV=4" 6.07 2194.8 - 565329 - - - 2.5967 - 1.917 0.338 - 212.4 1 2 0 0.0035 12 0 0 0 1.76E+07 2.76E+06 - - - 4.1112 0.999 221125_WJC_METTL3_EV_vs_WT_F09.10586.10586.4 1.08E-05 14/84 R.NDTK[136.11]EDVFVHQTAIK[136.11].R "sp|Q9Y2T7|YBOX2_HUMAN,sp|P67809|YBOX1_HUMAN,sp|P16989|YBOX3_HUMAN,tr|H0Y449|H0Y449_HUMAN,tr|A0A0D9SEI8|A0A0D9SEI8_HUMAN" 5 1759.9076 1.12 130361 10586 4 1759.912232 440.9842 Y-box-binding protein 2 OS=Homo sapiens OX=9606 GN=YBX2 PE=1 SV=2 5.38 2194.9 - 563884 - - - 2.6524 - 2.195 0.425 - 138 1 2 1 0.0047 15 0 0 0 9.75E+07 8.74E+07 - - - 3.2052 1 221125_WJC_METTL3_EV_vs_WT_F09.10609.10609.3 2.76E-09 16/76 R.GQVKPSTSSQPILSAPGPTK.L "sp|Q9ULT8|HECD1_HUMAN,tr|G3V4V5|G3V4V5_HUMAN,tr|A0A087X2H1|A0A087X2H1_HUMAN,tr|H0YJP0|H0YJP0_HUMAN" 4 1979.0688 0.69 130378 10609 3 1979.074039 660.6969 E3 ubiquitin-protein ligase HECTD1 OS=Homo sapiens OX=9606 GN=HECTD1 PE=1 SV=3 10 2198.1 - 340079 - - - 2.6699 - 3.029 0.617 - 267.9 1 2 0 0.0053 20 0 0 0 5.39E+06 7.81E+06 - - - 8.1061 0.9999 221125_WJC_METTL3_EV_vs_WT_F09.10610.10610.3 4.55E-07 18/52 K.HIQEVVNLQTQQNK.E "sp|Q9BYP7|WNK3_HUMAN,tr|A0A087WYK2|A0A087WYK2_HUMAN" 2 1677.8798 2.17 130379 10610 3 1677.885475 560.3006 Serine\threonine-protein kinase WNK3 OS=Homo sapiens OX=9606 GN=WNK3 PE=1 SV=3 6.75 2198.2 - 307951 - - - 3.3632 - 3.398 0.506 - 620.2 1 2 0 0.0056 14 0 0 0 6.47E+06 2.98E+06 - - - 7.4305 1 221125_WJC_METTL3_EV_vs_WT_F09.10611.10611.3 2.93E-09 15/64 K.QHLSNMEVQVASQSSQR.T sp|P12270|TPR_HUMAN 1 1927.917 2.53 130380 10611 3 1927.922224 643.6463 Nucleoprotein TPR OS=Homo sapiens OX=9606 GN=TPR PE=1 SV=3 6.75 2198.4 - 246834 - - - 2.6982 - 3.062 0.561 - 293.4 1 2 0 0.0052 17 0 0 0 7.42E+06 2.93E+06 - - - 7.6203 0.8165 221125_WJC_METTL3_EV_vs_WT_F09.10612.10612.4 4.93 May-72 K.DLEEDHAC[160.03]IPIK[136.11]K[136.11].S sp|P13639|EF2_HUMAN 1 1582.7996 0.51 130381 10612 4 1582.802396 396.7072 Elongation factor 2 OS=Homo sapiens OX=9606 GN=EEF2 PE=1 SV=4 4.75 2198.5 - 144330 - - - 1.7709 - 0.748 0.132 - 17.9 1 2 0 0.0028 13 0 0 0 1.69E+06 3.30E+06 - - - 0.2665 0.9404 221125_WJC_METTL3_EV_vs_WT_F09.10624.10624.3 7.86E-07 13/56 F.SQPPAPPHQNTFPPR.S sp|Q96I24|FUBP3_HUMAN 1 1669.8325 2.77 130389 10624 3 1669.839877 557.6181 Far upstream element-binding protein 3 OS=Homo sapiens OX=9606 GN=FUBP3 PE=1 SV=2 9.49 2200 - 311929 - - - 4.425 - 2.65 0.423 - 172 1 1 0 0.0074 15 0 0 0 7.06E+06 2.55E+06 - - - 5.797 0.9984 221125_WJC_METTL3_EV_vs_WT_F09.10625.10625.2 0.0202 12-Jun K.DNNLLGR[166.11].F "sp|P0DMV8|HS71A_HUMAN,sp|P34931|HS71L_HUMAN,sp|P0DMV9|HS71B_HUMAN,sp|P17066|HSP76_HUMAN,tr|Q53FA3|Q53FA3_HUMAN,tr|V9GZ37|V9GZ37_HUMAN,tr|A0A0G2JIW1|A0A0G2JIW1_HUMAN" 7 810.4223 0.23 130390 10625 2 810.423466 406.2184 Heat shock 70 kDa protein 1A OS=Homo sapiens OX=9606 GN=HSPA1A PE=1 SV=1 5.84 2200.2 - 215893 - - - 1.3943 - 1.377 0.313 - 266.6 1 2 0 0.0011 7 0 0 0 1.24E+06 5.40E+06 - - - 2.3661 0.9991 221125_WJC_METTL3_EV_vs_WT_F09.10626.10626.3 0.0358 Jul-48 K.DLEEDHAC[160.03]IPIK[136.11]K[136.11].S sp|P13639|EF2_HUMAN 1 1582.7996 0.58 130391 10626 3 1582.802712 528.6071 Elongation factor 2 OS=Homo sapiens OX=9606 GN=EEF2 PE=1 SV=4 4.75 2200.3 - 199166 - - - 1.9706 - 1.243 0.425 - 37.8 1 2 0 0.0031 13 0 0 0 1.77E+06 3.04E+06 - - - 3.8672 0.9953 221125_WJC_METTL3_EV_vs_WT_F09.10627.10627.3 0.00244 Oct-44 K.EQIQNQLDHLKR.V "sp|P14373|TRI27_HUMAN,tr|A0A0G2JIZ4|A0A0G2JIZ4_HUMAN" 2 1520.8059 1.2 130392 10627 3 1520.812596 507.9426 Zinc finger protein RFP OS=Homo sapiens OX=9606 GN=TRIM27 PE=1 SV=1 6.85 2200.4 - 162506 - - - 4.3773 - 1.89 0.324 - 153.8 1 2 0 0.0067 12 0 0 0 2.51E+06 2.08E+06 - - - 3.9149 0.9872 221125_WJC_METTL3_EV_vs_WT_F09.10630.10630.2 0.000949 28-May R.NDTKEDVFVHQTAIK.R "sp|Q9Y2T7|YBOX2_HUMAN,sp|P67809|YBOX1_HUMAN,sp|P16989|YBOX3_HUMAN,tr|H0Y449|H0Y449_HUMAN,tr|A0A0D9SEI8|A0A0D9SEI8_HUMAN" 5 1743.8792 1.42 130395 10630 2 1743.882244 872.9469 Y-box-binding protein 2 OS=Homo sapiens OX=9606 GN=YBX2 PE=1 SV=2 5.38 2200.8 - 70008.8 - - - 1.7662 - 1.305 0.431 - 71 1 2 1 0.0031 15 0 0 0 1.05E+06 7.43E+05 - - - 2.8779 0.9999 221125_WJC_METTL3_EV_vs_WT_F09.10635.10635.3 5.61E-05 Dec-44 K.EQIQNQLDHLK[136.11]R[166.11].V "sp|P14373|TRI27_HUMAN,tr|A0A0G2JIZ4|A0A0G2JIZ4_HUMAN" 2 1538.8284 1.21 130398 10635 3 1538.832105 513.9501 Zinc finger protein RFP OS=Homo sapiens OX=9606 GN=TRIM27 PE=1 SV=1 6.85 2201.6 - 135918 - - - 2.4018 - 2.322 0.506 - 221.7 1 2 0 0.0037 12 0 0 0 2.53E+06 2.08E+06 - - - 6.5155 1 221125_WJC_METTL3_EV_vs_WT_F09.10636.10636.3 0.000232 Dec-40 R.KNHEEEMLALR.G "sp|P08779|K1C16_HUMAN,tr|K7ENW6|K7ENW6_HUMAN" 2 1368.682 8.77 130399 10636 3 1368.682991 457.2346 "Keratin, type I cytoskeletal 16 OS=Homo sapiens OX=9606 GN=KRT16 PE=1 SV=4" 5.5 2201.7 - 350102 - - - 0.7357 - 2.321 0.469 - 256.6 1 2 0 0.001 11 0 0 0 6.39E+06 7.28E+05 - - - 6.1606 0.997 221125_WJC_METTL3_EV_vs_WT_F09.10637.10637.3 0.0265 Jun-56 K.NSSTIIQNPVETPKK.D sp|P38432|COIL_HUMAN 1 1654.889 1.09 130400 10637 3 1654.892045 552.6369 Coilin OS=Homo sapiens OX=9606 GN=COIL PE=1 SV=1 8.59 2201.8 - 160791 - - - 1.84 - 1.409 0.315 - 38.1 1 2 0 0.003 15 0 0 0 1.14E+07 1.04E+07 - - - 2.9458 1 221125_WJC_METTL3_EV_vs_WT_F09.10642.10642.3 4.60E-13 23/56 R.NDTK[136.11]EDVFVHQTAIK[136.11].R "sp|Q9Y2T7|YBOX2_HUMAN,sp|P67809|YBOX1_HUMAN,sp|P16989|YBOX3_HUMAN,tr|H0Y449|H0Y449_HUMAN,tr|A0A0D9SEI8|A0A0D9SEI8_HUMAN" 5 1759.9076 1.08 130402 10642 3 1759.912197 587.6431 Y-box-binding protein 2 OS=Homo sapiens OX=9606 GN=YBX2 PE=1 SV=2 5.38 2202.5 - 3.45E+06 - - - 2.6325 - 4.016 0.731 - 698.3 1 2 1 0.0046 15 0 0 0 8.46E+07 7.80E+07 - - - 10.3164 0.9954 221125_WJC_METTL3_EV_vs_WT_F09.10645.10645.3 1.78E-08 Nov-76 Q.DTELGSTHTAGATSSLTPSR[166.11].G sp|Q7Z434|MAVS_HUMAN 1 1997.9529 0.66 130405 10645 3 1997.95785 666.9916 Mitochondrial antiviral-signaling protein OS=Homo sapiens OX=9606 GN=MAVS PE=1 SV=2 5.32 2202.9 - 88717.1 - - - 2.454 - 2.417 0.597 - 158.9 1 1 0 0.0049 20 0 0 0 2.27E+06 3.43E+06 - - - 7.3356 0.9954 221125_WJC_METTL3_EV_vs_WT_F09.10650.10650.2 0.0648 14-Aug K.DIDIHEVR.L "sp|Q00839|HNRPU_HUMAN,tr|A0A1W2PQL0|A0A1W2PQL0_HUMAN,tr|A0A1W2PPL4|A0A1W2PPL4_HUMAN,tr|A0A1W2PQ74|A0A1W2PQ74_HUMAN,tr|Q5RI18|Q5RI18_HUMAN,tr|A0A1W2PP35|A0A1W2PP35_HUMAN,tr|A0A1W2PPS1|A0A1W2PPS1_HUMAN,tr|A0A1W2PRZ7|A0A1W2PRZ7_HUMAN,tr|A0A1W2PPH7|A0A1W2PPH7_HUMAN,tr|A0A1W2PP34|A0A1W2PP34_HUMAN,tr|A0A1X7SBS1|A0A1X7SBS1_HUMAN" 11 995.5036 1.44 130408 10650 2 995.506659 498.7591 Heterogeneous nuclear ribonucleoprotein U OS=Homo sapiens OX=9606 GN=HNRNPU PE=1 SV=6 4.54 2203.6 - 105433 - - - 3.0638 - 1.567 0.272 - 243.6 1 2 0 0.0031 8 0 0 0 2.45E+06 1.70E+06 - - - 2.4037 0.9634 221125_WJC_METTL3_EV_vs_WT_F09.10670.10670.3 3.86E-05 Oct-76 Q.DTELGSTHTAGATSSLTPSR.G sp|Q7Z434|MAVS_HUMAN 1 1987.9447 0.66 130422 10670 3 1987.953962 663.6555 Mitochondrial antiviral-signaling protein OS=Homo sapiens OX=9606 GN=MAVS PE=1 SV=2 5.32 2206.4 - 70497.5 - - - 4.6707 - 1.949 0.579 - 90.7 1 1 0 0.0093 20 0 0 0 2.27E+06 3.43E+06 - - - 6.6116 0.8928 221125_WJC_METTL3_EV_vs_WT_F09.10671.10671.3 0.394 Jul-48 R.KKVEAQLQELQVK.F sp|P35579|MYH9_HUMAN 1 1539.8984 0.92 130423 10671 3 1539.899402 514.3068 Myosin-9 OS=Homo sapiens OX=9606 GN=MYH9 PE=1 SV=4 8.5 2206.5 - 63490.4 - - - 0.6234 - 1.286 0.182 - 84.7 1 2 1 0.001 13 0 0 0 6.67E+07 7.23E+07 - - - 1.2508 0.9998 221125_WJC_METTL3_EV_vs_WT_F09.10673.10673.3 0.0228 Jul-80 R.VPSGGYSSINNVQDPQKPEPR.D "sp|Q9UKM7|MA1B1_HUMAN,tr|A0A804HL61|A0A804HL61_HUMAN,tr|A0A804HJ66|A0A804HJ66_HUMAN,tr|H0YI64|H0YI64_HUMAN" 4 2268.1135 1.87 130425 10673 3 2268.109494 757.0451 "Endoplasmic reticulum mannosyl-oligosaccharide 1,2-alpha-mannosidase OS=Homo sapiens OX=9606 GN=MAN1B1 PE=1 SV=2" 6.04 2206.8 - 52717.3 - - - -1.7548 - 1.65 0.468 - 38.2 1 2 0 -0.004 21 0 0 0 2.30E+07 1.23E+07 - - - 4.9572 0.953 221125_WJC_METTL3_EV_vs_WT_F09.10678.10678.3 0.283 Aug-56 K.NSSTIIQNPVETPK[136.11]K[136.11].D sp|P38432|COIL_HUMAN 1 1670.9174 1.09 130428 10678 3 1670.92199 557.9797 Coilin OS=Homo sapiens OX=9606 GN=COIL PE=1 SV=1 8.59 2207.5 - 311362 - - - 2.747 - 1.683 0.149 - 55.8 1 2 0 0.0046 15 0 0 0 1.14E+07 1.04E+07 - - - 1.5583 0.7888 221125_WJC_METTL3_EV_vs_WT_F09.10679.10679.4 1.07 Jul-84 K.DIK[136.11]PAATHHYLVVPK[136.11].K sp|Q9NQE9|HINT3_HUMAN 1 1703.9694 0.44 130429 10679 4 1703.973314 426.9996 Adenosine 5'-monophosphoramidase HINT3 OS=Homo sapiens OX=9606 GN=HINT3 PE=1 SV=1 8.51 2207.6 - 202013 - - - 2.3111 - 0.993 0.126 - 22.4 1 2 0 0.0039 15 0 0 0 1.99E+06 4.55E+06 - - - 0.3191 0.989 221125_WJC_METTL3_EV_vs_WT_F09.10680.10680.3 0.000345 Oct-56 K.GTEK[136.11]NPEISFTQSSR[166.11].K "sp|Q9BYW2|SETD2_HUMAN,tr|H7C3H4|H7C3H4_HUMAN,tr|H7BZ93|H7BZ93_HUMAN,tr|C9JG86|C9JG86_HUMAN,tr|H7BXT4|H7BXT4_HUMAN" 5 1697.8339 1.08 130430 10680 3 1697.839031 566.9519 Histone-lysine N-methyltransferase SETD2 OS=Homo sapiens OX=9606 GN=SETD2 PE=1 SV=3 6.14 2207.8 - 106711 - - - 2.9938 - 1.851 0.314 - 151.2 1 2 1 0.0051 15 0 0 0 2.34E+06 2.17E+06 - - - 3.646 0.9996 221125_WJC_METTL3_EV_vs_WT_F09.10684.10684.3 2.16E-05 16/48 R.K[136.11]K[136.11]VEAQLQELQVK[136.11].F sp|P35579|MYH9_HUMAN 1 1563.941 0.92 130432 10684 3 1563.945221 522.321 Myosin-9 OS=Homo sapiens OX=9606 GN=MYH9 PE=1 SV=4 8.5 2208.3 - 486564 - - - 2.6721 - 2.703 0.48 - 612.9 1 2 1 0.0042 13 0 0 0 6.67E+07 7.23E+07 - - - 6.5864 0.9339 221125_WJC_METTL3_EV_vs_WT_F09.10690.10690.3 8.65E-05 Oct-48 F.DDHDSVDK[136.11]IVIQK[136.11].Y "sp|Q32P51|RA1L2_HUMAN,sp|P09651|ROA1_HUMAN,tr|A0A7I2YQX9|A0A7I2YQX9_HUMAN,tr|F8VZ49|F8VZ49_HUMAN,tr|A0A7I2V3R8|A0A7I2V3R8_HUMAN,tr|F8VTQ5|F8VTQ5_HUMAN,tr|F8W6I7|F8W6I7_HUMAN,tr|H0YH80|H0YH80_HUMAN,tr|A0A7I2V2L6|A0A7I2V2L6_HUMAN,tr|A0A7I2V3W0|A0A7I2V3W0_HUMAN,tr|A0A2R8Y4L2|A0A2R8Y4L2_HUMAN" 11 1526.7911 1.52 130436 10690 3 1526.795371 509.9377 Heterogeneous nuclear ribonucleoprotein A1-like 2 OS=Homo sapiens OX=9606 GN=HNRNPA1L2 PE=2 SV=2 4.56 2209.2 - 228284 - - - 2.7731 - 2.096 0.492 - 94 1 1 1 0.0042 13 0 0 0 9.53E+06 6.27E+06 - - - 6.0306 1 221125_WJC_METTL3_EV_vs_WT_F09.10692.10692.4 3.03E-05 11/120 K.AATMTAAGHHAEVVVDPEDER[166.11].A "sp|Q13895|BYST_HUMAN,tr|F8WBL2|F8WBL2_HUMAN,tr|H7BY94|H7BY94_HUMAN" 3 2215.0203 0.86 130438 10692 4 2215.02141 554.7624 Bystin OS=Homo sapiens OX=9606 GN=BYSL PE=1 SV=3 4.49 2209.4 - 236862 - - - 0.4944 - 2.288 0.484 - 82.9 1 2 0 0.0011 21 0 0 0 3.47E+06 4.04E+06 - - - 3.7121 0.9918 221125_WJC_METTL3_EV_vs_WT_F09.10695.10695.3 0.0967 Apr-84 K.QAASTSGPTPAASQALNPQAQK[136.11].Q sp|Q92793|CBP_HUMAN 1 2131.0749 0.91 130441 10695 3 2131.075138 711.3656 CREB-binding protein OS=Homo sapiens OX=9606 GN=CREBBP PE=1 SV=3 8.75 2209.8 - 76778.5 - - - 0.107 - 1.151 0.303 - 11.6 5 2 0 0.0002 22 0 0 0 3.71E+06 4.07E+06 - - - 1.928 0.999 221125_WJC_METTL3_EV_vs_WT_F09.10696.10696.2 0.00131 Jun-34 K.ANDEANQSDTSVSLSEPK[136.11].S "sp|O95684|CEP43_HUMAN,tr|A0A087WV25|A0A087WV25_HUMAN" 2 1898.8585 2.63 130442 10696 2 1898.862399 950.4365 Centrosomal protein 43 OS=Homo sapiens OX=9606 GN=CEP43 PE=1 SV=1 3.92 2210 - 56500.7 - - - 2.0565 - 1.362 0.456 - 62.7 1 2 0 0.0039 18 0 0 0 2.30E+06 8.77E+05 - - - 3.1674 0.997 221125_WJC_METTL3_EV_vs_WT_F09.10700.10700.4 0.0102 14/72 R.KKVEAQLQELQVK.F sp|P35579|MYH9_HUMAN 1 1539.8984 0.95 130444 10700 4 1539.902082 385.9819 Myosin-9 OS=Homo sapiens OX=9606 GN=MYH9 PE=1 SV=4 8.5 2210.6 - 428721 - - - 2.3638 - 2.223 0.342 - 147.1 1 2 1 0.0036 13 0 0 0 1.55E+07 1.63E+07 - - - 2.498 0.9825 221125_WJC_METTL3_EV_vs_WT_F09.10701.10701.4 0.0321 Jul-78 K.VEYSEEELKTHISK.G "sp|P12956|XRCC6_HUMAN,tr|B1AHC9|B1AHC9_HUMAN" 2 1690.8414 1.11 130445 10701 4 1690.846329 423.7176 X-ray repair cross-complementing protein 6 OS=Homo sapiens OX=9606 GN=XRCC6 PE=1 SV=2 4.91 2210.7 - 199630 - - - 2.9264 - 1.348 0.293 - 27.1 1 2 1 0.0049 14 0 0 0 9.06E+06 8.14E+06 - - - 1.8836 0.9999 221125_WJC_METTL3_EV_vs_WT_F09.10709.10709.4 7.88E-06 Nov-78 K.VEYSEEELK[136.11]THISK[136.11].G "sp|P12956|XRCC6_HUMAN,tr|B1AHC9|B1AHC9_HUMAN" 2 1706.8698 1.11 130451 10709 4 1706.871005 427.7247 X-ray repair cross-complementing protein 6 OS=Homo sapiens OX=9606 GN=XRCC6 PE=1 SV=2 4.91 2211.8 - 358807 - - - 0.7171 - 1.962 0.531 - 65.2 1 2 1 0.0012 14 0 0 0 9.06E+06 8.14E+06 - - - 4.0928 0.9996 221125_WJC_METTL3_EV_vs_WT_F09.10711.10711.4 0.000278 14/72 R.K[136.11]K[136.11]VEAQLQELQVK[136.11].F sp|P35579|MYH9_HUMAN 1 1563.941 0.95 130453 10711 4 1563.942233 391.9925 Myosin-9 OS=Homo sapiens OX=9606 GN=MYH9 PE=1 SV=4 8.5 2212.1 - 948281 - - - 0.7615 - 2.173 0.43 - 185.1 1 2 1 0.0012 13 0 0 0 1.55E+07 1.63E+07 - - - 3.2561 1 221125_WJC_METTL3_EV_vs_WT_F09.10713.10713.3 6.23E-08 14/80 R.VPSGGYSSINNVQDPQK[136.11]PEPR[166.11].D "sp|Q9UKM7|MA1B1_HUMAN,tr|A0A804HL61|A0A804HL61_HUMAN,tr|A0A804HJ66|A0A804HJ66_HUMAN,tr|H0YI64|H0YI64_HUMAN" 4 2286.1359 1.87 130455 10713 3 2286.137046 763.0526 "Endoplasmic reticulum mannosyl-oligosaccharide 1,2-alpha-mannosidase OS=Homo sapiens OX=9606 GN=MAN1B1 PE=1 SV=2" 6.04 2212.3 - 254369 - - - 0.482 - 2.7 0.595 - 70.8 1 2 0 0.0011 21 0 0 0 2.30E+07 1.23E+07 - - - 7.5546 0.7863 221125_WJC_METTL3_EV_vs_WT_F09.10719.10719.3 0.709 Jul-64 K.AAEPGKLEQVRPQELSR.V "sp|Q14687|GSE1_HUMAN,tr|H7C3B5|H7C3B5_HUMAN,tr|H0Y613|H0Y613_HUMAN" 3 1907.0225 3.14 130461 10719 3 1907.022343 636.6814 Genetic suppressor element 1 OS=Homo sapiens OX=9606 GN=GSE1 PE=1 SV=3 6.27 2213.1 - 42220.8 - - - -0.0687 - 1.504 0.122 - 41.8 2 2 1 -0.0001 17 0 0 0 9.68E+06 3.08E+06 - - - 0.7919 0.9998 221125_WJC_METTL3_EV_vs_WT_F09.10723.10723.3 0.00273 Dec-52 K.VEYSEEELK[136.11]THISK[136.11].G "sp|P12956|XRCC6_HUMAN,tr|B1AHC9|B1AHC9_HUMAN" 2 1706.8698 1.33 130463 10723 3 1706.870673 569.9639 X-ray repair cross-complementing protein 6 OS=Homo sapiens OX=9606 GN=XRCC6 PE=1 SV=2 4.91 2213.6 - 316174 - - - 0.5226 - 2.486 0.483 - 187.7 1 2 1 0.0009 14 0 0 0 5.25E+06 3.95E+06 - - - 6.3449 0.9993 221125_WJC_METTL3_EV_vs_WT_F09.10730.10730.3 0.00973 Jul-84 K.QAASTSGPTPAASQALNPQAQK.Q sp|Q92793|CBP_HUMAN 1 2123.0607 0.91 130467 10730 3 2123.063493 708.6942 CREB-binding protein OS=Homo sapiens OX=9606 GN=CREBBP PE=1 SV=3 8.75 2214.6 - 130565 - - - 1.3108 - 1.625 0.361 - 24.3 1 2 0 0.0028 22 0 0 0 3.72E+06 4.07E+06 - - - 3.7151 0.9973 221125_WJC_METTL3_EV_vs_WT_F09.10741.10741.2 0.0446 14-Jun K.VGVNGFGR.L sp|P04406|G3P_HUMAN 1 804.4242 1.12 130474 10741 2 804.42472 403.2194 Glyceraldehyde-3-phosphate dehydrogenase OS=Homo sapiens OX=9606 GN=GAPDH PE=1 SV=3 9.72 2216.2 - 236309 - - - 0.6017 - 1.264 0.258 - 81.3 1 2 0 0.0005 8 0 0 0 4.75E+06 4.26E+06 - - - 1.653 0.9997 221125_WJC_METTL3_EV_vs_WT_F09.10749.10749.2 1.15E-06 30-Jul K.NSGQNLEEDMGQSEQK.A sp|Q9HAV7|GRPE1_HUMAN 1 1792.7534 1.51 130480 10749 2 1792.75677 897.384 "GrpE protein homolog 1, mitochondrial OS=Homo sapiens OX=9606 GN=GRPEL1 PE=1 SV=2" 4 2217.2 - 56285.3 - - - 1.896 - 1.686 0.617 - 41.3 1 2 0 0.0034 16 0 0 0 1.26E+06 8.34E+05 - - - 4.8813 0.9996 221125_WJC_METTL3_EV_vs_WT_F09.10750.10750.2 0.00203 30-Jun K.NSGQNLEEDMGQSEQK[136.11].A sp|Q9HAV7|GRPE1_HUMAN 1 1800.7676 1.51 130481 10750 2 1800.766546 901.3911 "GrpE protein homolog 1, mitochondrial OS=Homo sapiens OX=9606 GN=GRPEL1 PE=1 SV=2" 4 2217.4 - 47567.4 - - - -0.5692 - 1.685 0.419 - 100 1 2 0 -0.001 16 0 0 0 1.26E+06 8.34E+05 - - - 3.4182 1 221125_WJC_METTL3_EV_vs_WT_F09.10755.10755.2 1.82E-08 Nov-40 R.SDSPVPTAPTSGGPK[136.11]PSTASA.V "sp|Q86U44|MTA70_HUMAN,tr|B4E349|B4E349_HUMAN,tr|F5H6D8|F5H6D8_HUMAN,tr|B4DTN4|B4DTN4_HUMAN" 4 1918.9364 0.19 130484 10755 2 1918.932637 960.4755 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 5.55 2218.1 - 114309 - - - -1.9354 - 2.342 0.622 - 199.5 1 1 0 -0.0037 21 0 0 0 1.43E+06 7.38E+06 - - - 5.7262 0.9999 221125_WJC_METTL3_EV_vs_WT_F09.10760.10760.3 0.000556 Aug-76 R.AEIPC[160.03]EDEQEQEHNGPLDNK[136.11].G "sp|Q96SB4|SRPK1_HUMAN,tr|H3BLV9|H3BLV9_HUMAN,tr|H0Y932|H0Y932_HUMAN" 3 2359.0114 1.71 130487 10760 3 2359.009565 787.3444 SRSF protein kinase 1 OS=Homo sapiens OX=9606 GN=SRPK1 PE=1 SV=2 4 2218.7 - 205520 - - - -0.7707 - 1.428 0.552 - 32.2 1 2 0 -0.0018 20 0 0 0 8.80E+06 5.13E+06 - - - 5.5581 1 221125_WJC_METTL3_EV_vs_WT_F09.10769.10769.3 1.08E-09 20/76 R.SSLGQSASETEEDTVSVSK[136.11]K[136.11].E "sp|Q13435|SF3B2_HUMAN,tr|E9PPJ0|E9PPJ0_HUMAN,tr|H0YCG1|H0YCG1_HUMAN,tr|E9PJ04|E9PJ04_HUMAN" 4 2084.0092 0.87 130494 10769 3 2084.006204 695.677 Splicing factor 3B subunit 2 OS=Homo sapiens OX=9606 GN=SF3B2 PE=1 SV=2 4.41 2219.9 - 247423 - - - -1.4319 - 3.209 0.647 - 178.4 1 2 0 -0.003 20 0 0 0 2.84E+06 3.27E+06 - - - 8.5812 0.9999 221125_WJC_METTL3_EV_vs_WT_F09.10777.10777.3 3.72E-05 17/52 K.RPKEEEWDPEYTPK.S "sp|Q9NYF8|BCLF1_HUMAN,tr|H0YF14|H0YF14_HUMAN" 2 1802.8475 2.36 130500 10777 3 1802.847204 601.9565 Bcl-2-associated transcription factor 1 OS=Homo sapiens OX=9606 GN=BCLAF1 PE=1 SV=2 4.59 2221 - 518940 - - - -0.1803 - 3.014 0.443 - 512.3 1 2 1 -0.0003 14 0 0 0 3.66E+08 1.55E+08 - - - 6.4109 0.9998 221125_WJC_METTL3_EV_vs_WT_F09.10782.10782.3 0.00149 Sep-52 R.K[136.11]NPLPPSVGVVDK[136.11]K[136.11].E sp|Q8NC51|PAIRB_HUMAN 1 1500.909 0.79 130504 10782 3 1500.909439 501.3103 Plasminogen activator inhibitor 1 RNA-binding protein OS=Homo sapiens OX=9606 GN=SERBP1 PE=1 SV=2 9.7 2221.7 - 170156 - - - 0.2832 - 2.018 0.356 - 98.9 1 2 0 0.0004 14 0 0 0 3.00E+06 3.81E+06 - - - 4.3748 0.9999 221125_WJC_METTL3_EV_vs_WT_F09.10794.10794.3 5.81E-07 22/52 K.R[166.11]PK[136.11]EEEWDPEYTPK[136.11].S "sp|Q9NYF8|BCLF1_HUMAN,tr|H0YF14|H0YF14_HUMAN" 2 1828.8842 2.36 130513 10794 3 1828.886332 610.6353 Bcl-2-associated transcription factor 1 OS=Homo sapiens OX=9606 GN=BCLAF1 PE=1 SV=2 4.59 2223.2 - 541721 - - - 1.1663 - 3.446 0.56 - 942.5 1 2 1 0.0021 14 0 0 0 3.66E+08 1.55E+08 - - - 8.0708 0.9945 221125_WJC_METTL3_EV_vs_WT_F09.10796.10796.3 0.0675 Jun-64 R.STEEVKPIDENLGQTGK.S "sp|Q5T8D3|ACBD5_HUMAN,tr|A0A7I2YQE9|A0A7I2YQE9_HUMAN,tr|Q5T8E0|Q5T8E0_HUMAN,tr|A0A7I2V2Y9|A0A7I2V2Y9_HUMAN,tr|A0A7I2V462|A0A7I2V462_HUMAN,tr|A0A7I2V347|A0A7I2V347_HUMAN,tr|A0A7I2YQJ9|A0A7I2YQJ9_HUMAN,tr|A0A7I2V5L4|A0A7I2V5L4_HUMAN,tr|X6RDD7|X6RDD7_HUMAN,tr|A0A7I2V560|A0A7I2V560_HUMAN,tr|A0A7I2V420|A0A7I2V420_HUMAN,tr|A0A7I2V5E1|A0A7I2V5E1_HUMAN,tr|A0A7I2YQD7|A0A7I2YQD7_HUMAN,tr|A0A7I2V5U2|A0A7I2V5U2_HUMAN,tr|A0A7I2V2M2|A0A7I2V2M2_HUMAN,tr|B7Z2R7|B7Z2R7_HUMAN" 16 1843.9163 0.96 130515 10796 3 1843.91639 615.6461 Acyl-CoA-binding domain-containing protein 5 OS=Homo sapiens OX=9606 GN=ACBD5 PE=1 SV=1 4.41 2223.5 - 130204 - - - 0.0287 - 1.2 0.285 - 22.6 1 2 0 0.0001 17 0 0 0 2.14E+06 2.23E+06 - - - 2.1781 0.9999 221125_WJC_METTL3_EV_vs_WT_F09.10811.10811.4 4.98E-07 20/78 K.RPKEEEWDPEYTPK.S "sp|Q9NYF8|BCLF1_HUMAN,tr|H0YF14|H0YF14_HUMAN" 2 1802.8475 2.38 130526 10811 4 1802.849939 451.7192 Bcl-2-associated transcription factor 1 OS=Homo sapiens OX=9606 GN=BCLAF1 PE=1 SV=2 4.59 2225.4 - 2.35E+06 - - - 1.3368 - 2.911 0.551 - 379.7 1 2 1 0.0024 14 0 0 0 1.65E+08 6.94E+07 - - - 4.4101 0.9999 221125_WJC_METTL3_EV_vs_WT_F09.10812.10812.4 1.23E-05 20/78 K.R[166.11]PK[136.11]EEEWDPEYTPK[136.11].S "sp|Q9NYF8|BCLF1_HUMAN,tr|H0YF14|H0YF14_HUMAN" 2 1828.8842 2.39 130527 10812 4 1828.885733 458.2283 Bcl-2-associated transcription factor 1 OS=Homo sapiens OX=9606 GN=BCLAF1 PE=1 SV=2 4.59 2225.4 - 1.06E+06 - - - 0.8388 - 3.241 0.535 - 356.1 1 2 1 0.0015 14 0 0 0 1.65E+08 6.91E+07 - - - 4.3102 0.9968 221125_WJC_METTL3_EV_vs_WT_F09.10813.10813.3 0.0992 Oct-48 R.NPDTQWITK[136.11]PVHK[136.11].H "sp|P61313|RL15_HUMAN,tr|A0A2R8YEM3|A0A2R8YEM3_HUMAN,tr|E7EQV9|E7EQV9_HUMAN,tr|E7ENU7|E7ENU7_HUMAN" 4 1578.8489 0.86 130528 10813 3 1578.850746 527.2903 60S ribosomal protein L15 OS=Homo sapiens OX=9606 GN=RPL15 PE=1 SV=2 8.6 2225.6 - 418650 - - - 1.1527 - 1.635 0.247 - 87.2 1 2 0 0.0018 13 0 0 0 4.65E+06 5.44E+06 - - - 2.6263 0.9759 221125_WJC_METTL3_EV_vs_WT_F09.10816.10816.2 3.18 14-May K.LGDYGLAK[136.11].K "sp|Q8TD19|NEK9_HUMAN,tr|A0A7I2V5R1|A0A7I2V5R1_HUMAN,tr|G3V2Z5|G3V2Z5_HUMAN,tr|A0A7I2V454|A0A7I2V454_HUMAN,tr|G3V5V0|G3V5V0_HUMAN" 5 843.4582 5.22 130531 10816 2 843.458564 422.7364 Serine\threonine-protein kinase Nek9 OS=Homo sapiens OX=9606 GN=NEK9 PE=1 SV=2 5.83 2226 - 115414 - - - 0.4683 - 1.034 0.128 - 44.4 1 2 0 0.0004 8 0 0 0 7.99E+06 1.53E+06 - - - 0.0871 0.9431 221125_WJC_METTL3_EV_vs_WT_F09.10823.10823.2 4.46 14-May K.LGDYGLAK.K "sp|Q8TD19|NEK9_HUMAN,tr|A0A7I2V5R1|A0A7I2V5R1_HUMAN,tr|G3V2Z5|G3V2Z5_HUMAN,tr|A0A7I2V454|A0A7I2V454_HUMAN,tr|G3V5V0|G3V5V0_HUMAN" 5 835.444 5.23 130536 10823 2 835.444846 418.7293 Serine\threonine-protein kinase Nek9 OS=Homo sapiens OX=9606 GN=NEK9 PE=1 SV=2 5.83 2226.9 - 517444 - - - 1.0497 - 1.161 0.066 - 37.5 5 2 0 0.0009 8 0 0 0 8.01E+06 1.53E+06 - - - -0.3338 0.9997 221125_WJC_METTL3_EV_vs_WT_F09.10824.10824.3 2.94E-06 15/48 K.HRDYETATLSDIK.A "sp|O43707|ACTN4_HUMAN,tr|F5GXS2|F5GXS2_HUMAN,tr|H7C144|H7C144_HUMAN" 3 1547.758 1.27 130537 10824 3 1547.760205 516.9266 Alpha-actinin-4 OS=Homo sapiens OX=9606 GN=ACTN4 PE=1 SV=2 5.38 2227 - 247126 - - - 1.4337 - 3.007 0.402 - 257.5 1 2 1 0.0022 13 0 0 0 3.18E+07 2.51E+07 - - - 6.0063 1 221125_WJC_METTL3_EV_vs_WT_F09.10833.10833.3 0.000148 Dec-84 R.LSSEVSGSGSGNFGEEGNPQGK[136.11].E "sp|O14654|IRS4_HUMAN,tr|A0A804CF45|A0A804CF45_HUMAN" 2 2130.9545 0.63 130544 10833 3 2130.957358 711.3254 Insulin receptor substrate 4 OS=Homo sapiens OX=9606 GN=IRS4 PE=1 SV=1 4.25 2228.2 - 164603 - - - 1.3318 - 2.425 0.561 - 125.2 1 2 0 0.0028 22 0 0 0 2.15E+06 3.39E+06 - - - 6.894 1 221125_WJC_METTL3_EV_vs_WT_F09.10838.10838.3 4.20E-10 19/48 K.HR[166.11]DYETATLSDIK[136.11].A "sp|O43707|ACTN4_HUMAN,tr|F5GXS2|F5GXS2_HUMAN,tr|H7C144|H7C144_HUMAN" 3 1565.7805 1.24 130547 10838 3 1565.779775 522.9341 Alpha-actinin-4 OS=Homo sapiens OX=9606 GN=ACTN4 PE=1 SV=2 5.38 2228.9 - 540651 - - - -0.4349 - 3.712 0.61 - 805.1 1 2 1 -0.0007 13 0 0 0 3.19E+07 2.57E+07 - - - 8.8968 0.9897 221125_WJC_METTL3_EV_vs_WT_F09.10843.10843.2 0.0245 26-Jun K.RPKEEEWDPEYTPK.S "sp|Q9NYF8|BCLF1_HUMAN,tr|H0YF14|H0YF14_HUMAN" 2 1802.8475 4.11 130552 10843 2 1802.849768 902.431 Bcl-2-associated transcription factor 1 OS=Homo sapiens OX=9606 GN=BCLAF1 PE=1 SV=2 4.59 2229.6 - 98182.2 - - - 1.2419 - 1.579 0.355 - 106.5 1 2 1 0.0022 14 0 0 0 3.25E+06 7.89E+05 - - - 2.8086 0.9997 221125_WJC_METTL3_EV_vs_WT_F09.10845.10845.2 2.81E-05 May-42 R.LSSEVSGSGSGNFGEEGNPQGK[136.11].E "sp|O14654|IRS4_HUMAN,tr|A0A804CF45|A0A804CF45_HUMAN" 2 2130.9545 0.72 130554 10845 2 2130.951968 1066.4845 Insulin receptor substrate 4 OS=Homo sapiens OX=9606 GN=IRS4 PE=1 SV=1 4.25 2229.8 - 80612.4 - - - -1.1976 - 1.443 0.516 - 36.6 1 2 0 -0.0026 22 0 0 0 1.23E+06 1.71E+06 - - - 3.753 1 221125_WJC_METTL3_EV_vs_WT_F09.10857.10857.3 5.11E-06 Sep-64 R.THSTSSSLGSGESPFSR[166.11].S "sp|Q9UGV2|NDRG3_HUMAN,tr|Q5TH30|Q5TH30_HUMAN,tr|F8WBF9|F8WBF9_HUMAN" 3 1732.7892 1.02 130562 10857 3 1732.787753 578.6037 Protein NDRG3 OS=Homo sapiens OX=9606 GN=NDRG3 PE=1 SV=2 6.41 2231.4 - 146928 - - - -0.8212 - 2.253 0.532 - 99.3 1 2 0 -0.0014 17 0 0 0 5.15E+06 5.04E+06 - - - 6.5229 1 221125_WJC_METTL3_EV_vs_WT_F09.10873.10873.4 2.16E-05 16/96 R.IPHEPVINSSNVHVGSR.G sp|Q14966|ZN638_HUMAN 1 1840.9544 0.99 130573 10873 4 1840.955328 461.2459 Zinc finger protein 638 OS=Homo sapiens OX=9606 GN=ZNF638 PE=1 SV=2 6.92 2233.4 - 292562 - - - 0.5073 - 2.756 0.468 - 208.4 1 2 0 0.0009 17 0 0 0 1.58E+07 1.59E+07 - - - 3.6512 0.9999 221125_WJC_METTL3_EV_vs_WT_F09.10894.10894.4 0.00012 13/90 R.LEDTHFVQC[160.03]PSVPSHK.F "sp|Q7Z5L9|I2BP2_HUMAN,sp|Q9H1B7|I2BPL_HUMAN" 2 1879.8887 1.72 130587 10894 4 1879.887528 470.9794 Interferon regulatory factor 2-binding protein 2 OS=Homo sapiens OX=9606 GN=IRF2BP2 PE=1 SV=2 5.99 2236.1 - 806173 - - - -0.6144 - 2.264 0.402 - 102.5 1 2 0 -0.0012 16 0 0 0 6.21E+07 3.61E+07 - - - 3.0125 1 221125_WJC_METTL3_EV_vs_WT_F09.10895.10895.4 2.14E-07 14/90 R.LEDTHFVQC[160.03]PSVPSHK[136.11].F "sp|Q7Z5L9|I2BP2_HUMAN,sp|Q9H1B7|I2BPL_HUMAN" 2 1887.9029 1.72 130588 10895 4 1887.903434 472.983 Interferon regulatory factor 2-binding protein 2 OS=Homo sapiens OX=9606 GN=IRF2BP2 PE=1 SV=2 5.99 2236.2 - 513046 - - - 0.2919 - 2.959 0.518 - 132.6 1 2 0 0.0006 16 0 0 0 6.20E+07 3.61E+07 - - - 4.1167 1 221125_WJC_METTL3_EV_vs_WT_F09.10896.10896.3 2.70E-06 20/64 R.IPHEPVINSSNVHVGSR.G sp|Q14966|ZN638_HUMAN 1 1840.9544 0.83 130589 10896 3 1840.957886 614.6587 Zinc finger protein 638 OS=Homo sapiens OX=9606 GN=ZNF638 PE=1 SV=2 6.92 2236.3 - 284666 - - - 1.8968 - 3.955 0.654 - 556.8 1 2 0 0.0035 17 0 0 0 4.56E+06 5.48E+06 - - - 9.3041 1 221125_WJC_METTL3_EV_vs_WT_F09.10900.10900.4 7.70E-07 13/114 R.DTHPGSPGSPGPALR[166.11]PLPAR[166.11].E sp|Q8N0Y2|ZN444_HUMAN 1 1999.0502 1.46 130591 10900 4 1999.052335 500.7698 Zinc finger protein 444 OS=Homo sapiens OX=9606 GN=ZNF444 PE=1 SV=1 9.61 2236.9 - 230244 - - - 1.0445 - 2.142 0.531 - 104 1 2 0 0.0021 20 0 0 0 2.44E+07 1.67E+07 - - - 4.1019 0.9998 221125_WJC_METTL3_EV_vs_WT_F09.10903.10903.4 6.35E-07 13/114 R.DTHPGSPGSPGPALRPLPAR.E sp|Q8N0Y2|ZN444_HUMAN 1 1979.0337 1.46 130594 10903 4 1979.035125 495.7657 Zinc finger protein 444 OS=Homo sapiens OX=9606 GN=ZNF444 PE=1 SV=1 9.61 2237.2 - 224591 - - - 0.7165 - 2.448 0.385 - 87.4 1 2 0 0.0014 20 0 0 0 2.44E+07 1.67E+07 - - - 2.876 0.9988 221125_WJC_METTL3_EV_vs_WT_F09.10907.10907.3 2.11E-07 Sep-64 R.THSTSSSLGSGESPFSR.S "sp|Q9UGV2|NDRG3_HUMAN,tr|Q5TH30|Q5TH30_HUMAN,tr|F8WBF9|F8WBF9_HUMAN" 3 1722.7809 1.02 130596 10907 3 1722.786588 575.2676 Protein NDRG3 OS=Homo sapiens OX=9606 GN=NDRG3 PE=1 SV=2 6.41 2237.8 - 144524 - - - 3.2982 - 2.336 0.331 - 105.4 1 2 0 0.0057 17 0 0 0 5.15E+06 5.04E+06 - - - 4.3722 0.978 221125_WJC_METTL3_EV_vs_WT_F09.10915.10915.3 0.442 Jun-76 R.DTHPGSPGSPGPALRPLPAR.E sp|Q8N0Y2|ZN444_HUMAN 1 1979.0337 1.64 130602 10915 3 1979.032458 660.6852 Zinc finger protein 444 OS=Homo sapiens OX=9606 GN=ZNF444 PE=1 SV=1 9.61 2238.8 - 115532 - - - -0.6311 - 1.223 0.207 - 24.9 1 2 0 -0.0012 20 0 0 0 7.47E+06 4.54E+06 - - - 1.3359 0.9916 221125_WJC_METTL3_EV_vs_WT_F09.10916.10916.2 0.307 12-Jun K.SSFSITR[166.11].E "sp|Q9Y2W1|TR150_HUMAN,tr|A0A3B3ITZ9|A0A3B3ITZ9_HUMAN" 2 806.4162 2.45 130603 10916 2 806.416481 404.2154 Thyroid hormone receptor-associated protein 3 OS=Homo sapiens OX=9606 GN=THRAP3 PE=1 SV=2 9.47 2239 - 165099 - - - 0.3633 - 1.273 0.131 - 159.8 1 2 0 0.0003 7 0 0 0 7.13E+06 2.91E+06 - - - 0.7733 1 221125_WJC_METTL3_EV_vs_WT_F09.10921.10921.3 6.68E-05 15/92 K.SLAGSSGPGASSGTSGDHGELVVR.L "sp|P29692|EF1D_HUMAN,tr|E9PI39|E9PI39_HUMAN,tr|E9PMW7|E9PMW7_HUMAN,tr|E9PQ49|E9PQ49_HUMAN,tr|A0A087X1X7|A0A087X1X7_HUMAN,tr|E9PL12|E9PL12_HUMAN,tr|H0YCK7|H0YCK7_HUMAN,tr|E9PIZ1|E9PIZ1_HUMAN,tr|E9PPR1|E9PPR1_HUMAN,tr|E9PRY8|E9PRY8_HUMAN,tr|E9PK01|E9PK01_HUMAN" 11 2184.0407 1.5 130606 10921 3 2184.04235 729.0208 Elongation factor 1-delta OS=Homo sapiens OX=9606 GN=EEF1D PE=1 SV=5 5.3 2239.7 - 162928 - - - 0.7541 - 3.245 0.425 - 146.5 1 2 0 0.0016 24 0 0 0 7.82E+06 5.22E+06 - - - 6.0118 0.9998 221125_WJC_METTL3_EV_vs_WT_F09.10922.10922.3 0.000388 Jul-76 R.DTHPGSPGSPGPALR[166.11]PLPAR[166.11].E sp|Q8N0Y2|ZN444_HUMAN 1 1999.0502 1.64 130607 10922 3 1999.049112 667.3574 Zinc finger protein 444 OS=Homo sapiens OX=9606 GN=ZNF444 PE=1 SV=1 9.61 2239.8 - 121966 - - - -0.5678 - 1.545 0.435 - 28.6 1 2 0 -0.0011 20 0 0 0 7.47E+06 4.54E+06 - - - 4.4449 0.9999 221125_WJC_METTL3_EV_vs_WT_F09.10923.10923.3 2.27E-08 13/92 K.SLAGSSGPGASSGTSGDHGELVVR[166.11].L "sp|P29692|EF1D_HUMAN,tr|E9PI39|E9PI39_HUMAN,tr|E9PMW7|E9PMW7_HUMAN,tr|E9PQ49|E9PQ49_HUMAN,tr|A0A087X1X7|A0A087X1X7_HUMAN,tr|E9PL12|E9PL12_HUMAN,tr|H0YCK7|H0YCK7_HUMAN,tr|E9PIZ1|E9PIZ1_HUMAN,tr|E9PPR1|E9PPR1_HUMAN,tr|E9PRY8|E9PRY8_HUMAN,tr|E9PK01|E9PK01_HUMAN" 11 2194.049 1.5 130608 10923 3 2194.055368 732.3569 Elongation factor 1-delta OS=Homo sapiens OX=9606 GN=EEF1D PE=1 SV=5 5.3 2239.9 - 140730 - - - 2.9147 - 2.917 0.464 - 116.3 1 2 0 0.0064 24 0 0 0 7.82E+06 5.22E+06 - - - 6.1978 0.9991 221125_WJC_METTL3_EV_vs_WT_F09.10924.10924.3 0.0125 Jul-44 K.EYSGFAGVSRPR.G "sp|Q9NYF8|BCLF1_HUMAN,tr|H0YF63|H0YF63_HUMAN,tr|E9PK91|E9PK91_HUMAN,tr|H0YF14|H0YF14_HUMAN" 4 1324.6524 1.37 130609 10924 3 1324.654254 442.5581 Bcl-2-associated transcription factor 1 OS=Homo sapiens OX=9606 GN=BCLAF1 PE=1 SV=2 8.85 2240.1 - 137549 - - - 1.4011 - 1.201 0.406 - 65.6 1 2 0 0.0019 12 0 0 0 6.05E+06 4.42E+06 - - - 3.5737 1 221125_WJC_METTL3_EV_vs_WT_F09.10928.10928.3 4.63E-10 20/64 R.ATQQQHDFTLTQTADGR[166.11].S sp|P78527|PRKDC_HUMAN 1 1926.9059 0.8 130611 10928 3 1926.908305 643.3093 DNA-dependent protein kinase catalytic subunit OS=Homo sapiens OX=9606 GN=PRKDC PE=1 SV=3 5.21 2240.6 - 1.54E+06 - - - 1.2289 - 3.606 0.638 - 468.9 1 2 0 0.0024 17 0 0 0 2.12E+07 2.65E+07 - - - 8.8926 1 221125_WJC_METTL3_EV_vs_WT_F09.10930.10930.3 1.34E-09 17/64 R.ATQQQHDFTLTQTADGR.S sp|P78527|PRKDC_HUMAN 1 1916.8977 0.72 130613 10930 3 1916.901509 639.9732 DNA-dependent protein kinase catalytic subunit OS=Homo sapiens OX=9606 GN=PRKDC PE=1 SV=3 5.21 2240.8 - 1.05E+06 - - - 2.0043 - 3.228 0.651 - 292.2 1 2 0 0.0038 17 0 0 0 2.13E+07 2.97E+07 - - - 8.7574 0.9991 221125_WJC_METTL3_EV_vs_WT_F09.10939.10939.3 0.0218 Jul-44 K.LHGVNINVEASK[136.11].N "sp|Q9BWF3|RBM4_HUMAN,sp|Q9BQ04|RBM4B_HUMAN,tr|E9PM61|E9PM61_HUMAN,tr|D6R9K7|D6R9K7_HUMAN,tr|J3QRR5|J3QRR5_HUMAN,tr|E9PB51|E9PB51_HUMAN,tr|U3KQD5|U3KQD5_HUMAN,tr|E9PLB0|E9PLB0_HUMAN" 8 1287.7026 1.07 130620 10939 3 1287.704702 430.2415 RNA-binding protein 4 OS=Homo sapiens OX=9606 GN=RBM4 PE=1 SV=1 6.75 2242.1 - 120586 - - - 1.5935 - 1.377 0.386 - 43 1 2 0 0.0021 12 0 0 0 3.34E+06 3.11E+06 - - - 3.7297 0.9324 221125_WJC_METTL3_EV_vs_WT_F09.10941.10941.4 0.0638 Aug-96 L.LQDDAHPTLVTYADHSK[136.11].L "sp|Q86U44|MTA70_HUMAN,tr|F5H6D8|F5H6D8_HUMAN,tr|H0YFV6|H0YFV6_HUMAN,tr|B4DTN4|B4DTN4_HUMAN" 4 1917.9312 0 130622 10941 4 1917.930902 480.4901 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 5.13 2242.3 - 244671 - - - -0.1585 - 1.419 0.336 - 35.9 1 1 0 -0.0003 17 0 0 0 1.59E+04 4.92E+06 - - - 2.272 1 221125_WJC_METTL3_EV_vs_WT_F09.10948.10948.3 5.98E-09 20/60 R.LEDTHFVQC[160.03]PSVPSHK.F "sp|Q7Z5L9|I2BP2_HUMAN,sp|Q9H1B7|I2BPL_HUMAN" 2 1879.8887 2.03 130627 10948 3 1879.893388 627.6368 Interferon regulatory factor 2-binding protein 2 OS=Homo sapiens OX=9606 GN=IRF2BP2 PE=1 SV=2 5.99 2243.3 - 654168 - - - 2.5028 - 3.723 0.614 - 489.8 1 2 0 0.0047 16 0 0 0 2.00E+07 9.84E+06 - - - 8.7571 1 221125_WJC_METTL3_EV_vs_WT_F09.10949.10949.3 2.58E-09 13/60 R.LEDTHFVQC[160.03]PSVPSHK[136.11].F "sp|Q7Z5L9|I2BP2_HUMAN,sp|Q9H1B7|I2BPL_HUMAN" 2 1887.9029 2.03 130628 10949 3 1887.905676 630.3082 Interferon regulatory factor 2-binding protein 2 OS=Homo sapiens OX=9606 GN=IRF2BP2 PE=1 SV=2 5.99 2243.4 - 381915 - - - 1.4794 - 2.923 0.563 - 201.8 1 2 0 0.0028 16 0 0 0 2.00E+07 9.84E+06 - - - 7.5683 0.9985 221125_WJC_METTL3_EV_vs_WT_F09.10950.10950.4 0.00143 16/84 K.QDLPDAMKPHEIQEK.L sp|P62330|ARF6_HUMAN 1 1777.8669 1.46 130629 10950 4 1777.872352 445.474 ADP-ribosylation factor 6 OS=Homo sapiens OX=9606 GN=ARF6 PE=1 SV=2 4.75 2243.5 - 519085 - - - 3.0756 - 2.269 0.332 - 96.5 1 2 0 0.0055 15 0 0 0 1.33E+07 9.14E+06 - - - 2.4074 0.9999 221125_WJC_METTL3_EV_vs_WT_F09.10958.10958.3 1.85E-05 Oct-44 K.LHGVNINVEASK.N "sp|Q9BWF3|RBM4_HUMAN,sp|Q9BQ04|RBM4B_HUMAN,tr|E9PM61|E9PM61_HUMAN,tr|D6R9K7|D6R9K7_HUMAN,tr|J3QRR5|J3QRR5_HUMAN,tr|E9PB51|E9PB51_HUMAN,tr|U3KQD5|U3KQD5_HUMAN,tr|E9PLB0|E9PLB0_HUMAN" 8 1279.6885 1.14 130635 10958 3 1279.691061 427.5701 RNA-binding protein 4 OS=Homo sapiens OX=9606 GN=RBM4 PE=1 SV=1 6.75 2244.6 - 200119 - - - 2.0403 - 2.251 0.47 - 152.6 1 2 0 0.0026 12 0 0 0 3.33E+06 2.93E+06 - - - 6.0283 1 221125_WJC_METTL3_EV_vs_WT_F09.10960.10960.3 1.45E-08 14/72 K.SC[160.03]SGVEFSTSGHAYTDTGK.A "sp|Q9Y277|VDAC3_HUMAN,tr|E5RHE1|E5RHE1_HUMAN,tr|E5RJN6|E5RJN6_HUMAN,tr|E5RHZ6|E5RHZ6_HUMAN" 4 1989.8374 1.24 130637 10960 3 1989.837518 664.2864 Voltage-dependent anion-selective channel protein 3 OS=Homo sapiens OX=9606 GN=VDAC3 PE=1 SV=1 5.3 2244.9 - 169306 - - - 0.0417 - 3.167 0.725 - 200.7 1 2 0 0.0001 19 0 0 0 1.79E+07 1.44E+07 - - - 9.4552 1 221125_WJC_METTL3_EV_vs_WT_F09.10969.10969.3 8.45E-11 17/72 K.SC[160.03]SGVEFSTSGHAYTDTGK[136.11].A "sp|Q9Y277|VDAC3_HUMAN,tr|E5RHE1|E5RHE1_HUMAN,tr|E5RJN6|E5RJN6_HUMAN,tr|E5RHZ6|E5RHZ6_HUMAN" 4 1997.8516 1.24 130644 10969 3 1997.855419 666.9578 Voltage-dependent anion-selective channel protein 3 OS=Homo sapiens OX=9606 GN=VDAC3 PE=1 SV=1 5.3 2246.1 - 365213 - - - 1.894 - 3.609 0.733 - 251.4 1 2 0 0.0038 19 0 0 0 1.79E+07 1.44E+07 - - - 9.8643 0.9143 221125_WJC_METTL3_EV_vs_WT_F09.10970.10970.3 0.449 Jul-48 R.YTIHSQLEHLQSK.Y sp|Q9BWJ5|SF3B5_HUMAN 1 1582.8104 1.28 130645 10970 3 1582.813801 528.6107 Splicing factor 3B subunit 5 OS=Homo sapiens OX=9606 GN=SF3B5 PE=1 SV=1 6.92 2246.3 - 163038 - - - 2.1765 - 1.363 0.155 - 37.8 2 2 0 0.0034 13 0 0 0 3.16E+06 2.46E+06 - - - 0.9675 0.9996 221125_WJC_METTL3_EV_vs_WT_F09.10976.10976.4 0.00173 16/84 K.QDLPDAMK[136.11]PHEIQEK[136.11].L sp|P62330|ARF6_HUMAN 1 1793.8953 1.46 130648 10976 4 1793.89997 449.4811 ADP-ribosylation factor 6 OS=Homo sapiens OX=9606 GN=ARF6 PE=1 SV=2 4.75 2247.1 - 422240 - - - 2.6122 - 2.365 0.386 - 184.1 1 2 0 0.0047 15 0 0 0 1.33E+07 9.14E+06 - - - 2.8924 0.9994 221125_WJC_METTL3_EV_vs_WT_F09.10978.10978.3 0.0871 Nov-88 K.VAEQC[160.03]EPAESQPEALSEKEDVC[160.03]K.T "sp|P82094|TMF1_HUMAN,tr|F8WF45|F8WF45_HUMAN,tr|A0A2R8Y7M0|A0A2R8Y7M0_HUMAN" 3 2632.1633 2.1 130650 10978 3 2632.168464 878.395 TATA element modulatory factor OS=Homo sapiens OX=9606 GN=TMF1 PE=1 SV=2 4.06 2247.4 - 139926 - - - 1.9759 - 1.923 0.489 - 98.2 1 2 1 0.0052 23 0 0 0 4.90E+06 2.34E+06 - - - 5.5244 0.7746 221125_WJC_METTL3_EV_vs_WT_F09.10980.10980.3 0.296 Jun-88 K.VAEQC[160.03]EPAESQPEALSEK[136.11]EDVC[160.03]K[136.11].T "sp|P82094|TMF1_HUMAN,tr|F8WF45|F8WF45_HUMAN,tr|A0A2R8Y7M0|A0A2R8Y7M0_HUMAN" 3 2648.1917 2.1 130652 10980 3 2648.192487 883.7378 TATA element modulatory factor OS=Homo sapiens OX=9606 GN=TMF1 PE=1 SV=2 4.06 2247.6 - 100472 - - - 0.3112 - 1.26 0.15 - 26.1 1 2 1 0.0008 23 0 0 0 4.90E+06 2.34E+06 - - - 0.7543 1 221125_WJC_METTL3_EV_vs_WT_F09.10986.10986.3 4.75E-13 19/68 R.GSHTDAPDTATGNC[160.03]LLQR.A sp|Q9P2R3|ANFY1_HUMAN 1 1912.8697 1.48 130656 10986 3 1912.873105 638.6305 Rabankyrin-5 OS=Homo sapiens OX=9606 GN=ANKFY1 PE=1 SV=2 5.21 2248.4 - 422286 - - - 1.7602 - 3.404 0.7 - 600 1 2 0 0.0034 18 0 0 0 1.35E+07 9.12E+06 - - - 9.3936 0.9998 221125_WJC_METTL3_EV_vs_WT_F09.10987.10987.3 4.39E-06 13/44 R.TNTPVKEDWNVR.L "sp|P78347|GTF2I_HUMAN,tr|A0A494C0Q7|A0A494C0Q7_HUMAN,tr|A0A494C1K3|A0A494C1K3_HUMAN" 3 1457.7263 1.69 130657 10987 3 1457.728089 486.916 General transcription factor II-I OS=Homo sapiens OX=9606 GN=GTF2I PE=1 SV=2 5.74 2248.6 - 209894 - - - 1.2327 - 2.575 0.49 - 298 1 2 1 0.0018 12 0 0 0 6.52E+06 3.85E+06 - - - 6.6243 1 221125_WJC_METTL3_EV_vs_WT_F09.10995.10995.3 1.30E-08 18/68 R.GSHTDAPDTATGNC[160.03]LLQR[166.11].A sp|Q9P2R3|ANFY1_HUMAN 1 1922.878 1.47 130662 10995 3 1922.879471 641.9666 Rabankyrin-5 OS=Homo sapiens OX=9606 GN=ANKFY1 PE=1 SV=2 5.21 2249.7 - 466255 - - - 0.7608 - 3.234 0.67 - 323.9 1 2 0 0.0015 18 0 0 0 1.35E+07 9.19E+06 - - - 8.9321 0.9979 221125_WJC_METTL3_EV_vs_WT_F09.10996.10996.4 0.0116 Aug-84 K.IK[136.11]GEHPGLSIGDVAK[136.11].K "sp|B2RPK0|HGB1A_HUMAN,sp|P09429|HMGB1_HUMAN,tr|Q5T7C4|Q5T7C4_HUMAN" 3 1535.8642 0.21 130663 10996 4 1535.866703 384.9733 Putative high mobility group protein B1-like 1 OS=Homo sapiens OX=9606 GN=HMGB1P1 PE=5 SV=1 6.75 2249.8 - 245483 - - - 1.6024 - 1.543 0.35 - 32 1 2 1 0.0025 15 0 0 0 8.51E+05 4.15E+06 - - - 2.4269 0.9072 221125_WJC_METTL3_EV_vs_WT_F09.11001.11001.3 0.0598 Jun-48 R.K[136.11]PAAVLK[136.11]PSDWEK[136.11].S sp|Q9H0D6|XRN2_HUMAN 1 1491.8512 1.44 130666 11001 3 1491.856797 498.291 5'-3' exoribonuclease 2 OS=Homo sapiens OX=9606 GN=XRN2 PE=1 SV=1 8.5 2250.5 - 101933 - - - 3.7752 - 1.232 0.221 - 34.5 1 2 0 0.0056 13 0 0 0 6.78E+06 4.72E+06 - - - 1.5681 0.9972 221125_WJC_METTL3_EV_vs_WT_F09.11004.11004.3 0.00143 Jul-64 K.SNPSENEEK[136.11]EAQSQLIK[136.11].S sp|Q13217|DNJC3_HUMAN 1 1945.9564 2.88 130668 11004 3 1945.96057 649.6594 DnaJ homolog subfamily C member 3 OS=Homo sapiens OX=9606 GN=DNAJC3 PE=1 SV=1 4.49 2250.9 - 152376 - - - 2.1614 - 1.793 0.382 - 52.5 1 2 1 0.0042 17 0 0 0 1.87E+07 6.49E+06 - - - 4.2728 0.9997 221125_WJC_METTL3_EV_vs_WT_F09.11005.11005.3 1.90E-09 14/44 R.TNTPVK[136.11]EDWNVR[166.11].L "sp|P78347|GTF2I_HUMAN,tr|A0A494C0Q7|A0A494C0Q7_HUMAN,tr|A0A494C1K3|A0A494C1K3_HUMAN" 3 1475.7488 1.69 130669 11005 3 1475.753842 492.9235 General transcription factor II-I OS=Homo sapiens OX=9606 GN=GTF2I PE=1 SV=2 5.74 2251 - 206027 - - - 3.4423 - 2.523 0.596 - 329.2 1 2 1 0.0051 12 0 0 0 6.52E+06 3.85E+06 - - - 7.7486 1 221125_WJC_METTL3_EV_vs_WT_F09.11017.11017.3 2.05E-06 15/76 R.YFNKNEDVC[160.03]SC[160.03]STDTSEVPR.W sp|P49790|NU153_HUMAN 1 2407.0056 1.11 130677 11017 3 2407.005778 803.3425 Nuclear pore complex protein Nup153 OS=Homo sapiens OX=9606 GN=NUP153 PE=1 SV=2 4.32 2252.7 - 198595 - - - 0.0573 - 2.964 0.715 - 318 1 2 1 0.0001 20 0 0 0 1.49E+07 1.34E+07 - - - 9.1475 0.9999 221125_WJC_METTL3_EV_vs_WT_F09.11019.11019.3 8.92E-06 13/48 K.K[136.11]PLPDHVSIVEPK[136.11].D "sp|P23396|RS3_HUMAN,tr|H0YEU2|H0YEU2_HUMAN,tr|E9PSF4|E9PSF4_HUMAN,tr|E9PL09|E9PL09_HUMAN,tr|E9PPU1|E9PPU1_HUMAN" 5 1473.8526 0.58 130679 11019 3 1473.855511 492.2915 40S ribosomal protein S3 OS=Homo sapiens OX=9606 GN=RPS3 PE=1 SV=2 6.75 2253 - 234812 - - - 1.9649 - 2.157 0.521 - 226.3 1 2 0 0.0029 13 0 0 0 6.68E+06 1.15E+07 - - - 6.432 0.9938 221125_WJC_METTL3_EV_vs_WT_F09.11022.11022.3 0.129 Jun-68 K.ASQSR[166.11]PNSSALETLGGEK[136.11].L sp|O94804|STK10_HUMAN 1 1848.9296 0.87 130682 11022 3 1848.927709 617.3172 Serine\threonine-protein kinase 10 OS=Homo sapiens OX=9606 GN=STK10 PE=1 SV=1 6.19 2253.3 - 121645 - - - -1.0438 - 1.532 0.245 - 30.2 3 2 0 -0.0019 18 0 0 0 2.54E+06 2.92E+06 - - - 2.1124 1 221125_WJC_METTL3_EV_vs_WT_F09.11029.11029.3 9.79E-10 13/76 R.YFNK[136.11]NEDVC[160.03]SC[160.03]STDTSEVPR[166.11].W sp|P49790|NU153_HUMAN 1 2425.0281 1.11 130687 11029 3 2425.025588 809.35 Nuclear pore complex protein Nup153 OS=Homo sapiens OX=9606 GN=NUP153 PE=1 SV=2 4.32 2254.3 - 393856 - - - -1.04 - 2.917 0.776 - 229 1 2 1 -0.0025 20 0 0 0 1.49E+07 1.34E+07 - - - 9.7881 1 221125_WJC_METTL3_EV_vs_WT_F09.11040.11040.3 0.000202 13/60 K.QAQTQTSPEHLVLQQK.Q "sp|Q9ULV3|CIZ1_HUMAN,tr|Q5SYW2|Q5SYW2_HUMAN,tr|F5H2X7|F5H2X7_HUMAN,tr|H0Y5D5|H0Y5D5_HUMAN,tr|A0A494C0L7|A0A494C0L7_HUMAN,tr|Q9BTG3|Q9BTG3_HUMAN" 6 1834.9537 3 130695 11040 3 1834.955525 612.6585 Cip1-interacting zinc finger protein OS=Homo sapiens OX=9606 GN=CIZ1 PE=1 SV=2 6.75 2255.7 - 440605 - - - 0.9804 - 2.656 0.458 - 228.2 1 2 0 0.0018 16 0 0 0 4.50E+08 1.50E+08 - - - 6.1521 1 221125_WJC_METTL3_EV_vs_WT_F09.11041.11041.3 9.50E-06 14/64 K.DSSSTDSANEK[136.11]PALIPR[166.11].E "sp|Q9NUQ6|SPS2L_HUMAN,tr|C9JW67|C9JW67_HUMAN,tr|B8ZZZ7|B8ZZZ7_HUMAN,tr|C9JKE4|C9JKE4_HUMAN,tr|C9JGM8|C9JGM8_HUMAN,tr|F2Z2S1|F2Z2S1_HUMAN,tr|F8VZ02|F8VZ02_HUMAN,tr|F8W6C2|F8W6C2_HUMAN,tr|F8VT91|F8VT91_HUMAN" 9 1804.8922 1.3 130696 11041 3 1804.892061 602.638 SPATS2-like protein OS=Homo sapiens OX=9606 GN=SPATS2L PE=1 SV=2 4.56 2255.9 - 281567 - - - -0.072 - 2.737 0.484 - 217.8 1 2 0 -0.0001 17 0 0 0 1.62E+07 1.24E+07 - - - 6.4797 0.9999 221125_WJC_METTL3_EV_vs_WT_F09.11042.11042.3 0.00276 Oct-52 R.GHNTNVGAIVFHPK.S sp|O43172|PRP4_HUMAN 1 1489.779 2.43 130697 11042 3 1489.780776 497.6003 U4\U6 small nuclear ribonucleoprotein Prp4 OS=Homo sapiens OX=9606 GN=PRPF4 PE=1 SV=2 8.76 2256 - 203475 - - - 1.1948 - 2.071 0.432 - 125.4 1 2 0 0.0018 14 0 0 0 1.67E+07 6.89E+06 - - - 5.2906 0.9942 221125_WJC_METTL3_EV_vs_WT_F09.11050.11050.3 4.90E-08 16/56 F.SQPPAPPHQNTFPPR.S sp|Q96I24|FUBP3_HUMAN 1 1669.8325 3.47 130702 11050 3 1669.836061 557.6181 Far upstream element-binding protein 3 OS=Homo sapiens OX=9606 GN=FUBP3 PE=1 SV=2 9.49 2257 - 321028 - - - 2.1397 - 3.067 0.469 - 277.9 1 1 0 0.0036 15 0 0 0 1.08E+07 3.10E+06 - - - 6.6922 1 221125_WJC_METTL3_EV_vs_WT_F09.11056.11056.3 2.97E-10 18/60 R.HLQTHSNTIVVSLQSK[136.11].L "sp|Q13190|STX5_HUMAN,tr|H7C3X5|H7C3X5_HUMAN,tr|E9PNU4|E9PNU4_HUMAN" 3 1798.9781 1.08 130705 11056 3 1798.981509 600.6666 Syntaxin-5 OS=Homo sapiens OX=9606 GN=STX5 PE=1 SV=2 8.76 2257.8 - 482538 - - - 1.8972 - 3.305 0.583 - 527.3 1 2 0 0.0034 16 0 0 0 1.32E+07 1.22E+07 - - - 8.1063 0.9999 221125_WJC_METTL3_EV_vs_WT_F09.11057.11057.3 3.71E-05 Aug-52 R.GHNTNVGAIVFHPK[136.11].S sp|O43172|PRP4_HUMAN 1 1497.7932 2.85 130706 11057 3 1497.791945 500.2717 U4\U6 small nuclear ribonucleoprotein Prp4 OS=Homo sapiens OX=9606 GN=PRPF4 PE=1 SV=2 8.76 2257.9 - 186576 - - - -0.8352 - 1.93 0.407 - 76 1 2 0 -0.0013 14 0 0 0 1.70E+07 5.97E+06 - - - 4.8247 0.9917 221125_WJC_METTL3_EV_vs_WT_F09.11058.11058.3 0.00632 Aug-68 R.QSQANAPVYQQNVLHTGK[136.11].R "sp|Q9Y3S1|WNK2_HUMAN,tr|H0Y493|H0Y493_HUMAN,tr|F8W9F9|F8W9F9_HUMAN,tr|H0Y7R3|H0Y7R3_HUMAN,tr|H0Y7T5|H0Y7T5_HUMAN" 5 1990.0112 0.9 130707 11058 3 1990.0019 664.3443 Serine\threonine-protein kinase WNK2 OS=Homo sapiens OX=9606 GN=WNK2 PE=1 SV=4 8.6 2258.1 - 202844 - - - -4.6668 - 1.782 0.326 - 89.4 1 2 0 -0.0093 18 0 0 0 2.23E+06 2.48E+06 - - - 3.6106 1 221125_WJC_METTL3_EV_vs_WT_F09.11063.11063.4 1.01E-08 16/90 R.TTHYTPLAC[160.03]GSNPLK[136.11]R[166.11].E "sp|O60832|DKC1_HUMAN,tr|H7C2Q9|H7C2Q9_HUMAN,tr|C9IYT0|C9IYT0_HUMAN,tr|H7C0M1|H7C0M1_HUMAN" 4 1832.9322 0.56 130710 11063 4 1832.929978 459.2403 H\ACA ribonucleoprotein complex subunit DKC1 OS=Homo sapiens OX=9606 GN=DKC1 PE=1 SV=3 9.3 2258.7 - 448328 - - - -1.2243 - 2.484 0.583 - 224.8 1 2 0 -0.0022 16 0 0 0 5.95E+06 1.06E+07 - - - 4.6203 1 221125_WJC_METTL3_EV_vs_WT_F09.11065.11065.3 1.68E-06 Dec-68 R.QSQANAPVYQQNVLHTGK.R "sp|Q9Y3S1|WNK2_HUMAN,tr|H0Y493|H0Y493_HUMAN,tr|F8W9F9|F8W9F9_HUMAN,tr|H0Y7R3|H0Y7R3_HUMAN,tr|H0Y7T5|H0Y7T5_HUMAN" 5 1981.997 0.9 130712 11065 3 1981.999248 661.6729 Serine\threonine-protein kinase WNK2 OS=Homo sapiens OX=9606 GN=WNK2 PE=1 SV=4 8.6 2259 - 145889 - - - 1.1408 - 2.348 0.569 - 120.1 1 2 0 0.0023 18 0 0 0 2.23E+06 2.48E+06 - - - 7.0086 1 221125_WJC_METTL3_EV_vs_WT_F09.11069.11069.3 2.37E-07 13/60 K.QAQTQTSPEHLVLQQK[136.11].Q "sp|Q9ULV3|CIZ1_HUMAN,tr|Q5SYW2|Q5SYW2_HUMAN,tr|F5H2X7|F5H2X7_HUMAN,tr|H0Y5D5|H0Y5D5_HUMAN,tr|A0A494C0L7|A0A494C0L7_HUMAN,tr|Q9BTG3|Q9BTG3_HUMAN" 6 1842.9679 3.01 130714 11069 3 1842.968875 615.3299 Cip1-interacting zinc finger protein OS=Homo sapiens OX=9606 GN=CIZ1 PE=1 SV=2 6.75 2259.5 - 369025 - - - 0.5149 - 2.825 0.491 - 219.6 1 2 0 0.0009 16 0 0 0 4.50E+08 1.49E+08 - - - 6.6786 1 221125_WJC_METTL3_EV_vs_WT_F09.11070.11070.4 1.12E-08 14/90 R.TTHYTPLAC[160.03]GSNPLKR.E "sp|O60832|DKC1_HUMAN,tr|H7C2Q9|H7C2Q9_HUMAN,tr|C9IYT0|C9IYT0_HUMAN,tr|H7C0M1|H7C0M1_HUMAN" 4 1814.9098 0.56 130715 11070 4 1814.907396 454.7347 H\ACA ribonucleoprotein complex subunit DKC1 OS=Homo sapiens OX=9606 GN=DKC1 PE=1 SV=3 9.3 2259.6 - 277506 - - - -1.2981 - 2.695 0.565 - 148.8 1 2 0 -0.0024 16 0 0 0 5.92E+06 1.06E+07 - - - 4.4923 0.9995 221125_WJC_METTL3_EV_vs_WT_F09.11074.11074.3 7.61E-05 Jul-52 K.C[160.03]HGSGGSQQWTFGK.N sp|Q8NCW6|GLT11_HUMAN 1 1535.6576 0.97 130719 11074 3 1535.662833 512.8931 Polypeptide N-acetylgalactosaminyltransferase 11 OS=Homo sapiens OX=9606 GN=GALNT11 PE=1 SV=2 8.23 2260.2 - 120255 - - - 3.4337 - 1.564 0.488 - 71.2 1 2 0 0.0053 14 0 0 0 1.65E+06 1.71E+06 - - - 5.1678 0.9992 221125_WJC_METTL3_EV_vs_WT_F09.11075.11075.3 0.013 Jun-52 K.C[160.03]HGSGGSQQWTFGK[136.11].N sp|Q8NCW6|GLT11_HUMAN 1 1543.6718 0.97 130720 11075 3 1543.673244 515.5645 Polypeptide N-acetylgalactosaminyltransferase 11 OS=Homo sapiens OX=9606 GN=GALNT11 PE=1 SV=2 8.23 2260.3 - 83156 - - - 0.9613 - 1.289 0.39 - 58.2 1 2 0 0.0015 14 0 0 0 1.65E+06 1.71E+06 - - - 3.5624 1 221125_WJC_METTL3_EV_vs_WT_F09.11081.11081.3 1.07E-06 17/88 K.TLSSPSNRPSGETSVPPPPAVGR.M sp|Q8WWM7|ATX2L_HUMAN 1 2289.1713 1.69 130724 11081 3 2289.17031 764.0644 Ataxin-2-like protein OS=Homo sapiens OX=9606 GN=ATXN2L PE=1 SV=2 9.26 2261.1 - 277004 - - - -0.4425 - 3.035 0.528 - 206.6 1 2 0 -0.001 23 0 0 0 2.47E+08 1.46E+08 - - - 7.0309 0.9999 221125_WJC_METTL3_EV_vs_WT_F09.11082.11082.3 0.0205 14/88 K.TLSSPSNR[166.11]PSGETSVPPPPAVGR[166.11].M sp|Q8WWM7|ATX2L_HUMAN 1 2309.1879 1.69 130725 11082 3 2309.185822 770.7366 Ataxin-2-like protein OS=Homo sapiens OX=9606 GN=ATXN2L PE=1 SV=2 9.26 2261.3 - 176844 - - - -0.8839 - 2.472 0.402 - 154.1 1 2 0 -0.002 23 0 0 0 2.47E+08 1.46E+08 - - - 5.1445 0.9932 221125_WJC_METTL3_EV_vs_WT_F09.11083.11083.3 0.0425 Jul-48 K.KPLPDHVSIVEPK.D "sp|P23396|RS3_HUMAN,tr|H0YEU2|H0YEU2_HUMAN,tr|E9PSF4|E9PSF4_HUMAN,tr|E9PL09|E9PL09_HUMAN,tr|E9PPU1|E9PPU1_HUMAN" 5 1457.8242 0.57 130726 11083 3 1457.82817 486.9487 40S ribosomal protein S3 OS=Homo sapiens OX=9606 GN=RPS3 PE=1 SV=2 6.75 2261.4 - 124271 - - - 2.7129 - 1.306 0.315 - 53.3 1 2 0 0.004 13 0 0 0 6.01E+06 1.05E+07 - - - 2.7747 1 221125_WJC_METTL3_EV_vs_WT_F09.11089.11089.3 5.23E-13 19/64 K.DSSSTDSANEKPALIPR.E "sp|Q9NUQ6|SPS2L_HUMAN,tr|C9JW67|C9JW67_HUMAN,tr|B8ZZZ7|B8ZZZ7_HUMAN,tr|C9JKE4|C9JKE4_HUMAN,tr|C9JGM8|C9JGM8_HUMAN,tr|F2Z2S1|F2Z2S1_HUMAN,tr|F8VZ02|F8VZ02_HUMAN,tr|F8W6C2|F8W6C2_HUMAN,tr|F8VT91|F8VT91_HUMAN" 9 1786.8697 1.3 130730 11089 3 1786.872698 596.6305 SPATS2-like protein OS=Homo sapiens OX=9606 GN=SPATS2L PE=1 SV=2 4.56 2262.1 - 635868 - - - 1.666 - 3.372 0.67 - 402 1 2 0 0.003 17 0 0 0 1.62E+07 1.24E+07 - - - 9.0797 0.9999 221125_WJC_METTL3_EV_vs_WT_F09.11093.11093.3 3.13E-07 Nov-76 R.DGEDQTQDTELVETRPAGDR.T "sp|P01889|HLAB_HUMAN,tr|A0A140T951|A0A140T951_HUMAN,tr|Q2L6G2|Q2L6G2_HUMAN,tr|D5H3J5|D5H3J5_HUMAN,tr|S6AU73|S6AU73_HUMAN,tr|A0A140T9G0|A0A140T9G0_HUMAN,tr|A0A140T9H3|A0A140T9H3_HUMAN,tr|Q5SS57|Q5SS57_HUMAN,tr|D9J307|D9J307_HUMAN,tr|A0A140T9A9|A0A140T9A9_HUMAN,tr|A0A140T9S9|A0A140T9S9_HUMAN" 11 2230.9938 2.51 130734 11093 3 2230.999892 744.6719 "HLA class I histocompatibility antigen, B alpha chain OS=Homo sapiens OX=9606 GN=HLA-B PE=1 SV=3" 3.9 2262.7 - 104620 - - - 2.7252 - 2.725 0.488 - 140.4 1 2 0 0.0061 20 0 0 0 8.30E+05 3.31E+05 - - - 6.411 0.9997 221125_WJC_METTL3_EV_vs_WT_F09.11099.11099.2 1.37E-05 22-Nov K.GSFSDTGLGDGK.M "sp|Q9Y2W1|TR150_HUMAN,tr|A0A3B3ITZ9|A0A3B3ITZ9_HUMAN" 2 1139.5095 2.38 130738 11099 2 1139.512401 570.762 Thyroid hormone receptor-associated protein 3 OS=Homo sapiens OX=9606 GN=THRAP3 PE=1 SV=2 4.21 2263.5 - 495711 - - - 2.5616 - 2.232 0.61 - 255.3 1 2 0 0.0029 12 0 0 0 1.27E+07 5.32E+06 - - - 5.6581 1 221125_WJC_METTL3_EV_vs_WT_F09.11101.11101.3 4.95E-10 18/60 R.HLQTHSNTIVVSLQSK.L "sp|Q13190|STX5_HUMAN,tr|H7C3X5|H7C3X5_HUMAN,tr|E9PNU4|E9PNU4_HUMAN" 3 1790.9639 1.08 130740 11101 3 1790.96991 597.9952 Syntaxin-5 OS=Homo sapiens OX=9606 GN=STX5 PE=1 SV=2 8.76 2263.7 - 510990 - - - 3.358 - 3.593 0.601 - 545.4 1 2 0 0.006 16 0 0 0 1.32E+07 1.22E+07 - - - 8.5206 0.9995 221125_WJC_METTL3_EV_vs_WT_F09.11103.11103.3 0.195 Dec-32 R.EHLLDQLKR.K "sp|P52732|KIF11_HUMAN,tr|A0A7I2V3A9|A0A7I2V3A9_HUMAN" 2 1150.6459 4.33 130742 11103 3 1150.648485 384.5559 Kinesin-like protein KIF11 OS=Homo sapiens OX=9606 GN=KIF11 PE=1 SV=2 6.85 2264 - 415735 - - - 2.2848 - 2.414 0.298 - 312.9 1 2 0 0.0026 9 0 0 0 1.07E+07 2.46E+06 - - - 4.5177 1 221125_WJC_METTL3_EV_vs_WT_F09.11106.11106.3 1.27E-09 18/60 R.SSGPYGGGGQYFAK[136.11]PR[166.11].N "sp|P09651|ROA1_HUMAN,tr|A0A7I2YQX9|A0A7I2YQX9_HUMAN,tr|A0A7I2V5N7|A0A7I2V5N7_HUMAN,tr|A0A7I2V661|A0A7I2V661_HUMAN,tr|A0A7I2V520|A0A7I2V520_HUMAN,tr|A0A7I2V2F1|A0A7I2V2F1_HUMAN,tr|A0A7I2V497|A0A7I2V497_HUMAN,tr|A0A7I2V3K5|A0A7I2V3K5_HUMAN,tr|A0A7I2V2M7|A0A7I2V2M7_HUMAN,tr|A0A7I2V4P7|A0A7I2V4P7_HUMAN,tr|A0A7I2V5P1|A0A7I2V5P1_HUMAN,tr|A0A7I2V334|A0A7I2V334_HUMAN,tr|A0A7I2V4E2|A0A7I2V4E2_HUMAN,tr|A0A7I2V4F8|A0A7I2V4F8_HUMAN,tr|A0A7I2V3R8|A0A7I2V3R8_HUMAN,tr|F8W6I7|F8W6I7_HUMAN,tr|A0A7I2V666|A0A7I2V666_HUMAN,tr|A0A7I2V2Q7|A0A7I2V2Q7_HUMAN,tr|A0A7I2V459|A0A7I2V459_HUMAN,tr|A0A7I2YQY2|A0A7I2YQY2_HUMAN,tr|H0YH80|H0YH80_HUMAN,tr|A0A7I2V3W0|A0A7I2V3W0_HUMAN,tr|A0A7I2V3U8|A0A7I2V3U8_HUMAN,tr|A0A7I2V2R4|A0A7I2V2R4_HUMAN,tr|A0A7I2V2X1|A0A7I2V2X1_HUMAN,tr|A0A7I2V453|A0A7I2V453_HUMAN,tr|A0A7I2V360|A0A7I2V360_HUMAN" 27 1645.7968 1.39 130745 11106 3 1645.800508 549.6062 Heterogeneous nuclear ribonucleoprotein A1 OS=Homo sapiens OX=9606 GN=HNRNPA1 PE=1 SV=5 9.7 2264.4 - 231773 - - - 2.2682 - 2.765 0.62 - 457.6 1 2 0 0.0037 16 0 0 0 1.86E+07 1.34E+07 - - - 8.0609 1 221125_WJC_METTL3_EV_vs_WT_F09.11107.11107.3 1.61E-08 14/60 R.SSGPYGGGGQYFAKPR.N "sp|P09651|ROA1_HUMAN,tr|A0A7I2YQX9|A0A7I2YQX9_HUMAN,tr|A0A7I2V5N7|A0A7I2V5N7_HUMAN,tr|A0A7I2V661|A0A7I2V661_HUMAN,tr|A0A7I2V520|A0A7I2V520_HUMAN,tr|A0A7I2V2F1|A0A7I2V2F1_HUMAN,tr|A0A7I2V497|A0A7I2V497_HUMAN,tr|A0A7I2V3K5|A0A7I2V3K5_HUMAN,tr|A0A7I2V2M7|A0A7I2V2M7_HUMAN,tr|A0A7I2V4P7|A0A7I2V4P7_HUMAN,tr|A0A7I2V5P1|A0A7I2V5P1_HUMAN,tr|A0A7I2V334|A0A7I2V334_HUMAN,tr|A0A7I2V4E2|A0A7I2V4E2_HUMAN,tr|A0A7I2V4F8|A0A7I2V4F8_HUMAN,tr|A0A7I2V3R8|A0A7I2V3R8_HUMAN,tr|F8W6I7|F8W6I7_HUMAN,tr|A0A7I2V666|A0A7I2V666_HUMAN,tr|A0A7I2V2Q7|A0A7I2V2Q7_HUMAN,tr|A0A7I2V459|A0A7I2V459_HUMAN,tr|A0A7I2YQY2|A0A7I2YQY2_HUMAN,tr|H0YH80|H0YH80_HUMAN,tr|A0A7I2V3W0|A0A7I2V3W0_HUMAN,tr|A0A7I2V3U8|A0A7I2V3U8_HUMAN,tr|A0A7I2V2R4|A0A7I2V2R4_HUMAN,tr|A0A7I2V2X1|A0A7I2V2X1_HUMAN,tr|A0A7I2V453|A0A7I2V453_HUMAN,tr|A0A7I2V360|A0A7I2V360_HUMAN" 27 1627.7743 1.39 130746 11107 3 1627.776744 543.5987 Heterogeneous nuclear ribonucleoprotein A1 OS=Homo sapiens OX=9606 GN=HNRNPA1 PE=1 SV=5 9.7 2264.5 - 218468 - - - 1.4984 - 2.805 0.634 - 310.1 1 2 0 0.0024 16 0 0 0 1.86E+07 1.34E+07 - - - 8.2542 0.9997 221125_WJC_METTL3_EV_vs_WT_F09.11115.11115.4 2.37E-09 14/102 R.QRQPPLLGDHPAEYGEGR.G tr|A0A3B3ITJ4|A0A3B3ITJ4_HUMAN 1 2018.9922 1.29 130752 11115 4 2018.999186 505.7553 Heterogeneous nuclear ribonucleoprotein L (Fragment) OS=Homo sapiens OX=9606 GN=HNRNPL PE=1 SV=1 5.45 2265.6 - 147879 - - - 3.4423 - 2.792 0.585 - 124.5 1 2 1 0.0069 18 0 0 0 1.98E+07 1.54E+07 - - - 4.6676 0.9973 221125_WJC_METTL3_EV_vs_WT_F09.11117.11117.3 0.116 Jul-32 R.EHLLDQLK[136.11]R[166.11].K "sp|P52732|KIF11_HUMAN,tr|A0A7I2V3A9|A0A7I2V3A9_HUMAN" 2 1168.6683 4.33 130754 11117 3 1168.670726 390.5634 Kinesin-like protein KIF11 OS=Homo sapiens OX=9606 GN=KIF11 PE=1 SV=2 6.85 2265.9 - 161784 - - - 2.0536 - 1.504 0.299 - 73 1 2 0 0.0024 9 0 0 0 1.07E+07 2.46E+06 - - - 3.1029 0.9998 221125_WJC_METTL3_EV_vs_WT_F09.11118.11118.4 1.63E-06 11/102 R.QR[166.11]QPPLLGDHPAEYGEGR[166.11].G tr|A0A3B3ITJ4|A0A3B3ITJ4_HUMAN 1 2039.0088 1.29 130755 11118 4 2039.012926 510.7595 Heterogeneous nuclear ribonucleoprotein L (Fragment) OS=Homo sapiens OX=9606 GN=HNRNPL PE=1 SV=1 5.45 2266 - 128367 - - - 2.0353 - 2.692 0.517 - 83.5 1 2 1 0.0042 18 0 0 0 1.98E+07 1.54E+07 - - - 4.064 0.9996 221125_WJC_METTL3_EV_vs_WT_F09.11119.11119.3 6.29E-06 Dec-64 K.NKDVLQAETSQQLC[160.03]C[160.03]QK.F "sp|Q9UNH7|SNX6_HUMAN,tr|A0A0A0MRI2|A0A0A0MRI2_HUMAN" 2 2048.9619 2.01 130756 11119 3 2048.967527 683.9946 Sorting nexin-6 OS=Homo sapiens OX=9606 GN=SNX6 PE=1 SV=1 6.05 2266.1 - 120606 - - - 2.7346 - 2.279 0.551 - 173.7 1 2 1 0.0056 17 0 0 0 3.06E+06 1.52E+06 - - - 6.7626 0.997 221125_WJC_METTL3_EV_vs_WT_F09.11124.11124.2 0.0112 30-Apr K.QAQTQTSPEHLVLQQK.Q "sp|Q9ULV3|CIZ1_HUMAN,tr|Q5SYW2|Q5SYW2_HUMAN,tr|F5H2X7|F5H2X7_HUMAN,tr|H0Y5D5|H0Y5D5_HUMAN,tr|A0A494C0L7|A0A494C0L7_HUMAN,tr|Q9BTG3|Q9BTG3_HUMAN" 6 1834.9537 6.7 130761 11124 2 1834.955385 918.4841 Cip1-interacting zinc finger protein OS=Homo sapiens OX=9606 GN=CIZ1 PE=1 SV=2 6.75 2266.8 - 50112.9 - - - 0.9041 - 1.047 0.34 - 26.3 1 2 0 0.0017 16 0 0 0 1.01E+07 1.51E+06 - - - 1.6646 0.9992 221125_WJC_METTL3_EV_vs_WT_F09.11127.11127.3 2.40E-05 Dec-44 K.HK[136.11]LDVTSVEDYK[136.11].A "sp|P48643|TCPE_HUMAN,tr|E9PCA1|E9PCA1_HUMAN,tr|B7ZAR1|B7ZAR1_HUMAN,tr|E7ENZ3|E7ENZ3_HUMAN" 4 1448.7482 0.62 130762 11127 3 1448.753641 483.9233 T-complex protein 1 subunit epsilon OS=Homo sapiens OX=9606 GN=CCT5 PE=1 SV=1 5.38 2267.2 - 532324 - - - 3.7494 - 2.218 0.532 - 262.1 1 2 1 0.0054 12 0 0 0 5.98E+08 9.71E+08 - - - 6.6778 0.9997 221125_WJC_METTL3_EV_vs_WT_F09.11131.11131.3 0.00507 15/92 K.GEAAPGPAPPAPEATPPPASAAGK.D "sp|Q9NSI2|SLX9_HUMAN,tr|C9JJU7|C9JJU7_HUMAN" 2 2108.0538 2.98 130766 11131 3 2108.061163 703.6919 Ribosome biogenesis protein SLX9 homolog OS=Homo sapiens OX=9606 GN=SLX9 PE=1 SV=2 4.53 2267.8 - 217785 - - - 3.4767 - 2.597 0.468 - 189.8 1 2 0 0.0073 24 0 0 0 4.15E+07 1.39E+07 - - - 5.9723 0.9994 221125_WJC_METTL3_EV_vs_WT_F09.11132.11132.3 1.41E-05 Dec-44 K.HKLDVTSVEDYK.A "sp|P48643|TCPE_HUMAN,tr|E9PCA1|E9PCA1_HUMAN,tr|B7ZAR1|B7ZAR1_HUMAN,tr|E7ENZ3|E7ENZ3_HUMAN" 4 1432.7198 0.62 130767 11132 3 1432.723962 478.5805 T-complex protein 1 subunit epsilon OS=Homo sapiens OX=9606 GN=CCT5 PE=1 SV=1 5.38 2267.9 - 203469 - - - 2.8987 - 2.407 0.477 - 240.2 1 2 1 0.0042 12 0 0 0 5.99E+08 9.72E+08 - - - 6.2917 0.9998 221125_WJC_METTL3_EV_vs_WT_F09.11133.11133.2 4.03E-06 26-Oct R.SSFYPDGGDQETAK.T "sp|Q9NYF8|BCLF1_HUMAN,tr|H0YF00|H0YF00_HUMAN,tr|E9PKI6|E9PKI6_HUMAN,tr|A0A1W2PQ43|A0A1W2PQ43_HUMAN,tr|E9PK91|E9PK91_HUMAN,tr|E9PJA7|E9PJA7_HUMAN,tr|E9PK09|E9PK09_HUMAN,tr|E9PQN2|E9PQN2_HUMAN" 8 1500.6369 2.91 130768 11133 2 1500.638046 751.3257 Bcl-2-associated transcription factor 1 OS=Homo sapiens OX=9606 GN=BCLAF1 PE=1 SV=2 4.03 2268 - 139563 - - - 0.785 - 1.593 0.607 - 186.3 1 2 0 0.0012 14 0 0 0 1.46E+07 5.01E+06 - - - 4.6924 0.9994 221125_WJC_METTL3_EV_vs_WT_F09.11140.11140.2 0.0102 26-Jul R.SSFYPDGGDQETAK[136.11].T "sp|Q9NYF8|BCLF1_HUMAN,tr|H0YF00|H0YF00_HUMAN,tr|E9PKI6|E9PKI6_HUMAN,tr|A0A1W2PQ43|A0A1W2PQ43_HUMAN,tr|E9PK91|E9PK91_HUMAN,tr|E9PJA7|E9PJA7_HUMAN,tr|E9PK09|E9PK09_HUMAN,tr|E9PQN2|E9PQN2_HUMAN" 8 1508.6511 2.91 130773 11140 2 1508.650068 755.3328 Bcl-2-associated transcription factor 1 OS=Homo sapiens OX=9606 GN=BCLAF1 PE=1 SV=2 4.03 2269 - 157138 - - - -0.6628 - 1.265 0.446 - 69.3 1 2 0 -0.001 14 0 0 0 1.46E+07 5.01E+06 - - - 2.9247 0.9933 221125_WJC_METTL3_EV_vs_WT_F09.11144.11144.4 0.00361 Aug-90 R.NEC[160.03]FLQHKDDNPNLPR.L "sp|P02768|ALBU_HUMAN,tr|A0A087WWT3|A0A087WWT3_HUMAN,tr|H7C013|H7C013_HUMAN,tr|A0A0C4DGB6|A0A0C4DGB6_HUMAN" 4 1995.9221 15.52 130777 11144 4 1995.927732 499.9878 Albumin OS=Homo sapiens OX=9606 GN=ALB PE=1 SV=2 5.38 2269.5 - 150914 - - - 2.8177 - 1.727 0.327 - 55.7 1 2 1 0.0056 16 0 0 0 6.01E+06 3.87E+05 - - - 2.2631 1 221125_WJC_METTL3_EV_vs_WT_F09.11148.11148.3 0.000145 16/92 K.GEAAPGPAPPAPEATPPPASAAGK[136.11].D "sp|Q9NSI2|SLX9_HUMAN,tr|C9JJU7|C9JJU7_HUMAN" 2 2116.068 2.98 130779 11148 3 2116.069599 706.3633 Ribosome biogenesis protein SLX9 homolog OS=Homo sapiens OX=9606 GN=SLX9 PE=1 SV=2 4.53 2270.1 - 150038 - - - 0.7396 - 2.725 0.548 - 222 1 2 0 0.0016 24 0 0 0 4.14E+07 1.39E+07 - - - 6.9776 0.9998 221125_WJC_METTL3_EV_vs_WT_F09.11150.11150.4 6.63E-06 12/114 R.MSVTEGGIKYPETTEGGRPK.L "sp|P24928|RPB1_HUMAN,tr|A0A6Q8PGB0|A0A6Q8PGB0_HUMAN" 2 2136.0521 2.25 130781 11150 4 2136.054985 535.0203 DNA-directed RNA polymerase II subunit RPB1 OS=Homo sapiens OX=9606 GN=POLR2A PE=1 SV=2 5.99 2270.3 - 162120 - - - 1.3417 - 2.111 0.502 - 53.3 1 2 1 0.0029 20 0 0 0 5.71E+06 2.54E+06 - - - 3.8444 0.9941 221125_WJC_METTL3_EV_vs_WT_F09.11157.11157.3 6.32E-10 19/76 A.SSLVSGLNSSASEPAK[136.11]EPAK[136.11].K "sp|Q86U44|MTA70_HUMAN,tr|F5H6D8|F5H6D8_HUMAN,tr|H0YFV6|H0YFV6_HUMAN,tr|B4DTN4|B4DTN4_HUMAN" 4 1974.024 0.001 130785 11157 3 1974.022766 659.0153 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 5.86 2271.3 - 856854 - - - -0.6504 - 3.897 0.54 - 359.4 1 1 1 -0.0013 20 0 0 0 0.00E+00 5.47E+07 - - - 7.86 0.9994 221125_WJC_METTL3_EV_vs_WT_F09.11158.11158.4 0.0122 11/132 K.TLSSPSNRPSGETSVPPPPAVGR.M sp|Q8WWM7|ATX2L_HUMAN 1 2289.1713 1.86 130786 11158 4 2289.175027 573.3001 Ataxin-2-like protein OS=Homo sapiens OX=9606 GN=ATXN2L PE=1 SV=2 9.26 2271.4 - 216138 - - - 1.6181 - 1.964 0.341 - 89.5 1 2 0 0.0037 23 0 0 0 1.13E+07 6.07E+06 - - - 2.4117 1 221125_WJC_METTL3_EV_vs_WT_F09.11164.11164.3 1.39E-15 26/84 R.LLEGEDAHLSSQQASGQSYSSR.E sp|P08779|K1C16_HUMAN 1 2349.0833 877.01 130790 11164 3 2349.08252 784.035 "Keratin, type I cytoskeletal 16 OS=Homo sapiens OX=9606 GN=KRT16 PE=1 SV=4" 4.65 2272.2 - 1.20E+06 - - - -0.3303 - 4.429 0.769 - 609.3 1 2 0 -0.0008 22 0 0 0 2.11E+09 2.40E+06 - - - 10.6416 1 221125_WJC_METTL3_EV_vs_WT_F09.11165.11165.2 2.53E-07 16/22 K.HKLDVTSVEDYK.A "sp|P48643|TCPE_HUMAN,tr|E9PCA1|E9PCA1_HUMAN,tr|B7ZAR1|B7ZAR1_HUMAN,tr|E7ENZ3|E7ENZ3_HUMAN" 4 1432.7198 0.65 130791 11165 2 1432.718883 717.3672 T-complex protein 1 subunit epsilon OS=Homo sapiens OX=9606 GN=CCT5 PE=1 SV=1 5.38 2272.4 - 252998 - - - -0.6463 - 2.839 0.608 - 788.6 1 2 1 -0.0009 12 0 0 0 3.61E+07 5.60E+07 - - - 6.2769 0.9994 221125_WJC_METTL3_EV_vs_WT_F09.11167.11167.3 0.000509 Sep-44 R.TNAENEFVTIKK.D sp|P04264|K2C1_HUMAN 1 1392.7249 999 130793 11167 3 1392.727439 465.2489 "Keratin, type II cytoskeletal 1 OS=Homo sapiens OX=9606 GN=KRT1 PE=1 SV=6" 5.81 2272.6 - 166089 - - - 1.8266 - 1.356 0.421 - 116.9 1 2 0 0.0025 12 0 0 0 1.01E+08 0.00E+00 - - - 4.0772 0.9999 221125_WJC_METTL3_EV_vs_WT_F09.11168.11168.3 2.18E-09 13/68 R.QRQPPLLGDHPAEYGEGR.G tr|A0A3B3ITJ4|A0A3B3ITJ4_HUMAN 1 2018.9922 1.8 130794 11168 3 2018.994662 674.0047 Heterogeneous nuclear ribonucleoprotein L (Fragment) OS=Homo sapiens OX=9606 GN=HNRNPL PE=1 SV=1 5.45 2272.7 - 158393 - - - 1.2016 - 2.737 0.607 - 130.1 1 2 1 0.0024 18 0 0 0 8.93E+06 4.96E+06 - - - 7.814 0.9989 221125_WJC_METTL3_EV_vs_WT_F09.11174.11174.3 0.0509 Oct-44 K.HKLDVTSVEDYK[136.11].A "sp|P48643|TCPE_HUMAN,tr|E9PCA1|E9PCA1_HUMAN,tr|B7ZAR1|B7ZAR1_HUMAN,tr|E7ENZ3|E7ENZ3_HUMAN" 4 1440.734 - 130799 11174 3 1440.73205 481.2519 T-complex protein 1 subunit epsilon OS=Homo sapiens OX=9606 GN=CCT5 PE=1 SV=1 5.38 2273.5 - 359625 - - - -1.3597 - 1.765 0.401 - 118.2 1 2 1 -0.002 12 0 0 0 - - - - - 4.585 0.9999 221125_WJC_METTL3_EV_vs_WT_F09.11179.11179.3 1.42E-07 14/68 R.QR[166.11]QPPLLGDHPAEYGEGR[166.11].G tr|A0A3B3ITJ4|A0A3B3ITJ4_HUMAN 1 2039.0088 1.73 130801 11179 3 2039.004662 680.6769 Heterogeneous nuclear ribonucleoprotein L (Fragment) OS=Homo sapiens OX=9606 GN=HNRNPL PE=1 SV=1 5.45 2274.1 - 190237 - - - -2.0176 - 2.771 0.58 - 214.4 1 2 1 -0.0041 18 0 0 0 8.60E+06 4.96E+06 - - - 7.5432 0.9751 221125_WJC_METTL3_EV_vs_WT_F09.11183.11183.2 0.696 12-May R.LAADDFR.T "sp|Q04695|K1C17_HUMAN,sp|P13645|K1C10_HUMAN,sp|O76015|KRT38_HUMAN,sp|Q2M2I5|K1C24_HUMAN,sp|Q15323|K1H1_HUMAN,sp|P02533|K1C14_HUMAN,sp|P05783|K1C18_HUMAN,sp|P08727|K1C19_HUMAN,sp|P08779|K1C16_HUMAN,sp|Q7Z3Y7|K1C28_HUMAN,sp|Q14532|K1H2_HUMAN,sp|P19012|K1C15_HUMAN,sp|O76013|KRT36_HUMAN,sp|Q14525|KT33B_HUMAN,sp|Q92764|KRT35_HUMAN,sp|O76014|KRT37_HUMAN,sp|P13646|K1C13_HUMAN,tr|F8VZY9|F8VZY9_HUMAN,tr|K7EPJ9|K7EPJ9_HUMAN,tr|C9JM50|C9JM50_HUMAN,tr|A0A1B0GVI3|A0A1B0GVI3_HUMAN,tr|K7EMD9|K7EMD9_HUMAN,tr|F5GWP8|F5GWP8_HUMAN,tr|K7ERE3|K7ERE3_HUMAN,tr|C4AM86|C4AM86_HUMAN" 25 806.3923 170.55 130803 11183 2 806.38967 404.2034 "Keratin, type I cytoskeletal 17 OS=Homo sapiens OX=9606 GN=KRT17 PE=1 SV=2" 4.21 2274.7 - 157812 - - - -3.2205 - 1.181 0.211 - 87.9 1 2 0 -0.0026 7 0 0 0 2.20E+07 1.29E+05 - - - 1.1258 0.9997 221125_WJC_METTL3_EV_vs_WT_F09.11190.11190.4 0.000553 Oct-90 R.GGEVLDSSHDDIK[136.11]LEK[136.11].S sp|O76031|CLPX_HUMAN 1 1756.8814 0.91 130808 11190 4 1756.880392 440.2276 "ATP-dependent Clp protease ATP-binding subunit clpX-like, mitochondrial OS=Homo sapiens OX=9606 GN=CLPX PE=1 SV=2" 4.43 2275.7 - 210766 - - - -0.5783 - 1.603 0.451 - 37.9 1 2 1 -0.001 16 0 0 0 6.05E+06 6.66E+06 - - - 3.3174 0.9995 221125_WJC_METTL3_EV_vs_WT_F09.11196.11196.4 8.16E-06 Dec-90 R.GGEVLDSSHDDIKLEK.S sp|O76031|CLPX_HUMAN 1 1740.853 0.9 130812 11196 4 1740.848497 436.2205 "ATP-dependent Clp protease ATP-binding subunit clpX-like, mitochondrial OS=Homo sapiens OX=9606 GN=CLPX PE=1 SV=2" 4.43 2276.5 - 169903 - - - -2.5913 - 2.194 0.463 - 68.3 1 2 1 -0.0045 16 0 0 0 6.02E+06 6.66E+06 - - - 3.5315 0.9979 221125_WJC_METTL3_EV_vs_WT_F09.11199.11199.4 0.0232 9/132 K.KLPPPPGSPLGHSPTASPPPTAR.K "sp|O95785|WIZ_HUMAN,tr|A0A669KBG4|A0A669KBG4_HUMAN,tr|A0A2R8YFV2|A0A2R8YFV2_HUMAN,tr|A0A669KAV7|A0A669KAV7_HUMAN,tr|M0QXA7|M0QXA7_HUMAN,tr|A0A669KBH9|A0A669KBH9_HUMAN,tr|B9EGQ5|B9EGQ5_HUMAN" 7 2258.2172 2.14 130813 11199 4 2258.219005 565.5616 Protein Wiz OS=Homo sapiens OX=9606 GN=WIZ PE=1 SV=2 11 2276.9 - 183680 - - - 0.821 - 2.321 0.259 - 42.8 1 2 0 0.0019 23 0 0 0 4.23E+07 1.97E+07 - - - 1.7526 0.9999 221125_WJC_METTL3_EV_vs_WT_F09.11201.11201.4 5.69E-06 13/126 R.LLEGEDAHLSSQQASGQSYSSR.E sp|P08779|K1C16_HUMAN 1 2349.0833 1.92 130814 11201 4 2349.083791 588.2781 "Keratin, type I cytoskeletal 16 OS=Homo sapiens OX=9606 GN=KRT16 PE=1 SV=4" 4.65 2277.1 - 1.44E+06 - - - 0.2107 - 2.278 0.457 - 114.3 1 2 0 0.0005 22 0 0 0 5.74E+07 2.99E+07 - - - 3.473 1 221125_WJC_METTL3_EV_vs_WT_F09.11203.11203.2 3.95E-14 19/42 R.LLEGEDAHLSSQQASGQSYSSR.E sp|P08779|K1C16_HUMAN 1 2349.0833 999 130816 11203 2 2349.078917 1175.5489 "Keratin, type I cytoskeletal 16 OS=Homo sapiens OX=9606 GN=KRT16 PE=1 SV=4" 4.65 2277.4 - 345777 - - - -1.8641 - 3.89 0.763 - 637.5 1 2 0 -0.0044 22 0 0 0 1.97E+07 0.00E+00 - - - 8.0149 0.9998 221125_WJC_METTL3_EV_vs_WT_F09.11208.11208.2 6.82E-07 22-Oct R.TNAENEFVTIKK.D sp|P04264|K2C1_HUMAN 1 1392.7249 999 130818 11208 2 1392.721967 697.3697 "Keratin, type II cytoskeletal 1 OS=Homo sapiens OX=9606 GN=KRT1 PE=1 SV=6" 5.81 2278.1 - 265300 - - - -2.1024 - 2.497 0.547 - 325.9 1 2 0 -0.0029 12 0 0 0 8.70E+06 0.00E+00 - - - 5.488 0.9999 221125_WJC_METTL3_EV_vs_WT_F09.11217.11217.3 8.69E-07 13/80 K.QISSSSTGC[160.03]LSSPNATVQSPK.H sp|Q9Y6Y0|NS1BP_HUMAN 1 2135.0165 3.63 130824 11217 3 2135.024088 712.6794 Influenza virus NS1A-binding protein OS=Homo sapiens OX=9606 GN=IVNS1ABP PE=1 SV=3 8.22 2279.1 - 215386 - - - 3.5719 - 2.746 0.586 - 211.5 1 2 0 0.0076 21 0 0 0 1.12E+07 3.08E+06 - - - 7.493 1 221125_WJC_METTL3_EV_vs_WT_F09.11221.11221.3 1.39E-11 23/120 C.NVGAGGPAPAAGAAPAGGPAPSTAAAPAEEK.K sp|P05386|RLA1_HUMAN 1 2582.2725 2.02 130826 11221 3 2582.270178 861.7648 60S acidic ribosomal protein P1 OS=Homo sapiens OX=9606 GN=RPLP1 PE=1 SV=1 4.53 2279.7 - 319218 - - - -0.8969 - 4.43 0.639 - 346.7 1 1 0 -0.0023 31 0 0 0 3.29E+07 1.63E+07 - - - 9.0878 0.9999 221125_WJC_METTL3_EV_vs_WT_F09.11240.11240.3 3.76E-08 16/52 K.KSVEEGKIDGIIDK.T sp|Q96A49|SYAP1_HUMAN 1 1529.8301 1.35 130836 11240 3 1529.826656 510.9506 Synapse-associated protein 1 OS=Homo sapiens OX=9606 GN=SYAP1 PE=1 SV=1 4.78 2282.2 - 445637 - - - -2.2434 - 2.865 0.56 - 255.8 1 2 1 -0.0034 14 0 0 0 2.61E+08 1.93E+08 - - - 7.5797 0.9992 221125_WJC_METTL3_EV_vs_WT_F09.11241.11241.3 0.0236 Sep-64 R.EIVHLQAGQC[160.03]GNQIGAK.F "sp|P04350|TBB4A_HUMAN,sp|Q9BVA1|TBB2B_HUMAN,sp|P07437|TBB5_HUMAN,sp|Q13509|TBB3_HUMAN,sp|Q13885|TBB2A_HUMAN,sp|P68371|TBB4B_HUMAN,tr|M0R2D3|M0R2D3_HUMAN,tr|G3V3W7|G3V3W7_HUMAN,tr|M0R2T4|M0R2T4_HUMAN,tr|G3V3R4|G3V3R4_HUMAN,tr|M0R042|M0R042_HUMAN,tr|M0QY85|M0QY85_HUMAN,tr|M0QZL7|M0QZL7_HUMAN,tr|G3V5W4|G3V5W4_HUMAN,tr|M0R0X0|M0R0X0_HUMAN,tr|M0QYM7|M0QYM7_HUMAN,tr|G3V4U2|G3V4U2_HUMAN,tr|M0R278|M0R278_HUMAN,tr|M0QY37|M0QY37_HUMAN,tr|G3V2R8|G3V2R8_HUMAN,tr|G3V3J6|G3V3J6_HUMAN,tr|M0QX14|M0QX14_HUMAN,tr|G3V2N6|G3V2N6_HUMAN" 23 1821.9156 0.45 130837 11241 3 1821.913134 608.3125 Tubulin beta-4A chain OS=Homo sapiens OX=9606 GN=TUBB4A PE=1 SV=2 6.83 2282.3 - 295968 - - - -1.3349 - 2.044 0.29 - 117.8 1 2 0 -0.0024 17 0 0 0 5.69E+06 1.27E+07 - - - 3.5786 0.9999 221125_WJC_METTL3_EV_vs_WT_F09.11246.11246.3 0.00689 20/52 K.K[136.11]SVEEGK[136.11]IDGIIDK[136.11].T sp|Q96A49|SYAP1_HUMAN 1 1553.8727 1.35 130840 11246 3 1553.870402 518.9648 Synapse-associated protein 1 OS=Homo sapiens OX=9606 GN=SYAP1 PE=1 SV=1 4.78 2283 - 793120 - - - -1.4712 - 3.481 0.552 - 433.6 1 2 1 -0.0023 14 0 0 0 2.60E+08 1.93E+08 - - - 8.0084 0.9834 221125_WJC_METTL3_EV_vs_WT_F09.11247.11247.3 0.0712 Sep-48 R.SLENYHFVDEHGK.D sp|Q14677|EPN4_HUMAN 1 1573.7161 0.86 130841 11247 3 1573.712704 525.5793 Clathrin interactor 1 OS=Homo sapiens OX=9606 GN=CLINT1 PE=1 SV=1 5.26 2283.1 - 416291 - - - -2.1713 - 1.501 0.205 - 56.9 1 2 0 -0.0034 13 0 0 0 2.49E+07 2.90E+07 - - - 1.9257 0.9983 221125_WJC_METTL3_EV_vs_WT_F09.11255.11255.3 2.59E-07 Dec-56 K.AK[136.11]DLQDELAGNSEQR[166.11].K sp|Q9UQE7|SMC3_HUMAN 1 1690.8241 0.68 130847 11255 3 1690.821978 564.6153 Structural maintenance of chromosomes protein 3 OS=Homo sapiens OX=9606 GN=SMC3 PE=1 SV=2 4.32 2284.1 - 781124 - - - -1.2621 - 2.63 0.276 - 193.3 1 2 1 -0.0021 15 0 0 0 1.57E+07 2.32E+07 - - - 4.1398 0.9986 221125_WJC_METTL3_EV_vs_WT_F09.11256.11256.4 6.33E-07 17/78 K.KSVEEGKIDGIIDK.T sp|Q96A49|SYAP1_HUMAN 1 1529.8301 1.27 130848 11256 4 1529.826534 383.4648 Synapse-associated protein 1 OS=Homo sapiens OX=9606 GN=SYAP1 PE=1 SV=1 4.78 2284.3 - 554300 - - - -2.3231 - 3.072 0.368 - 221.4 1 2 1 -0.0036 14 0 0 0 6.88E+07 5.41E+07 - - - 2.8366 0.9995 221125_WJC_METTL3_EV_vs_WT_F09.11257.11257.4 0.000212 Nov-78 K.K[136.11]SVEEGK[136.11]IDGIIDK[136.11].T sp|Q96A49|SYAP1_HUMAN 1 1553.8727 1.27 130849 11257 4 1553.869587 389.4754 Synapse-associated protein 1 OS=Homo sapiens OX=9606 GN=SYAP1 PE=1 SV=1 4.78 2284.4 - 502123 - - - -1.9957 - 2.295 0.438 - 107.9 1 2 1 -0.0031 14 0 0 0 6.86E+07 5.39E+07 - - - 3.3398 0.9936 221125_WJC_METTL3_EV_vs_WT_F09.11263.11263.3 1.10E-08 16/72 S.SLVSGLNSSASEPAK[136.11]EPAK[136.11].K "sp|Q86U44|MTA70_HUMAN,tr|F5H6D8|F5H6D8_HUMAN,tr|H0YFV6|H0YFV6_HUMAN,tr|B4DTN4|B4DTN4_HUMAN" 4 1886.992 0.001 130853 11263 3 1886.989637 630.0046 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 5.86 2285.2 - 375897 - - - -1.2639 - 2.966 0.604 - 175.9 1 1 1 -0.0024 19 0 0 0 0.00E+00 2.95E+07 - - - 7.9444 0.9999 221125_WJC_METTL3_EV_vs_WT_F09.11264.11264.3 1.52E-06 Dec-48 R.SLENYHFVDEHGK[136.11].D sp|Q14677|EPN4_HUMAN 1 1581.7303 0.86 130854 11264 3 1581.727255 528.2507 Clathrin interactor 1 OS=Homo sapiens OX=9606 GN=CLINT1 PE=1 SV=1 5.26 2285.3 - 544258 - - - -1.9384 - 2.227 0.518 - 110.8 1 2 0 -0.0031 13 0 0 0 2.49E+07 2.90E+07 - - - 6.4851 1 221125_WJC_METTL3_EV_vs_WT_F09.11269.11269.3 1.86E-06 16/60 K.QAQTQTSPEHLVLQQK.Q "sp|Q9ULV3|CIZ1_HUMAN,tr|Q5SYW2|Q5SYW2_HUMAN,tr|F5H2X7|F5H2X7_HUMAN,tr|H0Y5D5|H0Y5D5_HUMAN,tr|A0A494C0L7|A0A494C0L7_HUMAN,tr|Q9BTG3|Q9BTG3_HUMAN" 6 1834.9537 3.01 130858 11269 3 1834.952523 612.6585 Cip1-interacting zinc finger protein OS=Homo sapiens OX=9606 GN=CIZ1 PE=1 SV=2 6.75 2286 - 3.23E+06 - - - -0.6556 - 3.084 0.505 - 375.9 1 2 0 -0.0012 16 0 0 0 4.50E+08 1.49E+08 - - - 7.0597 0.9999 221125_WJC_METTL3_EV_vs_WT_F09.11271.11271.4 0.000248 13/72 R.SLENYHFVDEHGK[136.11].D sp|Q14677|EPN4_HUMAN 1 1581.7303 1.74 130859 11271 4 1581.728856 396.4399 Clathrin interactor 1 OS=Homo sapiens OX=9606 GN=CLINT1 PE=1 SV=1 5.26 2286.2 - 707819 - - - -0.9262 - 1.85 0.466 - 89.4 1 2 0 -0.0015 13 0 0 0 2.76E+07 1.59E+07 - - - 3.5098 0.9999 221125_WJC_METTL3_EV_vs_WT_F09.11276.11276.4 8.45E-06 17/72 R.SLENYHFVDEHGK.D sp|Q14677|EPN4_HUMAN 1 1573.7161 1.74 130862 11276 4 1573.71322 394.4363 Clathrin interactor 1 OS=Homo sapiens OX=9606 GN=CLINT1 PE=1 SV=1 5.26 2286.9 - 1.01E+06 - - - -1.8434 - 2.408 0.468 - 159.9 1 2 0 -0.0029 13 0 0 0 2.76E+07 1.59E+07 - - - 3.6245 0.9131 221125_WJC_METTL3_EV_vs_WT_F09.11291.11291.2 1.26E-05 26-Oct K.K[136.11]SVEEGK[136.11]IDGIIDK[136.11].T sp|Q96A49|SYAP1_HUMAN 1 1553.8727 2.94 130873 11291 2 1553.86346 777.9436 Synapse-associated protein 1 OS=Homo sapiens OX=9606 GN=SYAP1 PE=1 SV=1 4.78 2288.8 - 236206 - - - -5.9387 - 2.467 0.353 - 266.4 1 2 1 -0.0092 14 0 0 0 1.07E+07 3.62E+06 - - - 3.9114 0.9548 221125_WJC_METTL3_EV_vs_WT_F09.11302.11302.3 0.172 Jul-36 R.LKYENEVALR.Q "sp|P13645|K1C10_HUMAN,tr|A0A1B0GVI3|A0A1B0GVI3_HUMAN" 2 1233.6717 14.19 130878 11302 3 1233.668134 412.2312 "Keratin, type I cytoskeletal 10 OS=Homo sapiens OX=9606 GN=KRT10 PE=1 SV=6" 6.14 2290.1 - 358156 - - - -2.9206 - 1.242 0.306 - 65.3 1 2 1 -0.0036 10 0 0 0 4.34E+07 3.06E+06 - - - 2.5835 0.9872 221125_WJC_METTL3_EV_vs_WT_F09.11331.11331.4 50.7 2/102 G.ASC[160.03]C[160.03]PC[160.03]C[160.03]C[160.03]C[160.03]C[160.03]GC[160.03]PDRPGR.R sp|Q9BXQ6|T121B_HUMAN 1 2288.7553 999 130887 11331 4 2288.745288 573.1961 Transmembrane protein 121B OS=Homo sapiens OX=9606 GN=TMEM121B PE=2 SV=1 7.74 2294 - 1.45E+06 - - - -4.3653 - 0.48 0.692 - 1.6 1 1 0 -0.01 18 0 0 0 5.86E+07 0.00E+00 - - - 4.995 0.9992 221125_WJC_METTL3_EV_vs_WT_F09.11344.11344.4 1.78E-09 28/90 K.IFVGGIK[136.11]EDTEEHHLR[166.11].D "sp|Q32P51|RA1L2_HUMAN,sp|P09651|ROA1_HUMAN,sp|P22626|ROA2_HUMAN,tr|A0A7I2YQN4|A0A7I2YQN4_HUMAN,tr|A0A7I2YQX9|A0A7I2YQX9_HUMAN,tr|A0A7I2V4N0|A0A7I2V4N0_HUMAN,tr|A0A024RA28|A0A024RA28_HUMAN,tr|A0A7I2V4N1|A0A7I2V4N1_HUMAN,tr|A0A7I2V4I6|A0A7I2V4I6_HUMAN,tr|F8VZ49|F8VZ49_HUMAN,tr|A0A7I2V3R8|A0A7I2V3R8_HUMAN,tr|A0A087WUI2|A0A087WUI2_HUMAN,tr|A0A7I2V4S4|A0A7I2V4S4_HUMAN,tr|F8VTQ5|F8VTQ5_HUMAN,tr|F8W6I7|F8W6I7_HUMAN,tr|A0A7I2V2L6|A0A7I2V2L6_HUMAN,tr|A0A7I2V323|A0A7I2V323_HUMAN,tr|A0A7I2V3W0|A0A7I2V3W0_HUMAN,tr|A0A7I2V5U9|A0A7I2V5U9_HUMAN,tr|A0A2R8Y4L2|A0A2R8Y4L2_HUMAN,tr|A0A7I2V3P1|A0A7I2V3P1_HUMAN,tr|A0A7I2V3P7|A0A7I2V3P7_HUMAN" 22 1896.9813 1.17 130891 11344 4 1896.971373 475.2526 Heterogeneous nuclear ribonucleoprotein A1-like 2 OS=Homo sapiens OX=9606 GN=HNRNPA1L2 PE=2 SV=2 5.36 2295.6 - 2.53E+06 - - - -5.223 - 4.341 0.606 - 856.8 1 2 1 -0.0099 16 0 0 0 1.17E+08 9.99E+07 - - - 5.015 1 221125_WJC_METTL3_EV_vs_WT_F09.11363.11363.3 9.80E-10 20/60 K.IFVGGIKEDTEEHHLR.D "sp|Q32P51|RA1L2_HUMAN,sp|P09651|ROA1_HUMAN,sp|P22626|ROA2_HUMAN,tr|A0A7I2YQN4|A0A7I2YQN4_HUMAN,tr|A0A7I2YQX9|A0A7I2YQX9_HUMAN,tr|A0A7I2V4N0|A0A7I2V4N0_HUMAN,tr|A0A024RA28|A0A024RA28_HUMAN,tr|A0A7I2V4N1|A0A7I2V4N1_HUMAN,tr|A0A7I2V4I6|A0A7I2V4I6_HUMAN,tr|F8VZ49|F8VZ49_HUMAN,tr|A0A7I2V3R8|A0A7I2V3R8_HUMAN,tr|A0A087WUI2|A0A087WUI2_HUMAN,tr|A0A7I2V4S4|A0A7I2V4S4_HUMAN,tr|F8VTQ5|F8VTQ5_HUMAN,tr|F8W6I7|F8W6I7_HUMAN,tr|A0A7I2V2L6|A0A7I2V2L6_HUMAN,tr|A0A7I2V323|A0A7I2V323_HUMAN,tr|A0A7I2V3W0|A0A7I2V3W0_HUMAN,tr|A0A7I2V5U9|A0A7I2V5U9_HUMAN,tr|A0A2R8Y4L2|A0A2R8Y4L2_HUMAN,tr|A0A7I2V3P1|A0A7I2V3P1_HUMAN,tr|A0A7I2V3P7|A0A7I2V3P7_HUMAN" 22 1878.9588 1.37 130901 11363 3 1878.962714 627.3269 Heterogeneous nuclear ribonucleoprotein A1-like 2 OS=Homo sapiens OX=9606 GN=HNRNPA1L2 PE=2 SV=2 5.36 2297.8 - 1.29E+06 - - - 2.0772 - 3.481 0.672 - 587.7 1 2 1 0.0039 16 0 0 0 3.46E+07 2.53E+07 - - - 9.2315 1 221125_WJC_METTL3_EV_vs_WT_F09.11366.11366.3 2.27E-12 26/84 R.ISC[160.03]GGGINVDVNQHPDGGPGGK.A sp|Q96F45|ZN503_HUMAN 1 2133.9862 1.9 130902 11366 3 2133.985003 712.336 Zinc finger protein 503 OS=Homo sapiens OX=9606 GN=ZNF503 PE=1 SV=1 5.21 2298.2 - 6.47E+06 - - - -0.5445 - 4.744 0.686 - 752.4 1 2 0 -0.0012 22 0 0 0 2.54E+08 1.34E+08 - - - 9.879 1 221125_WJC_METTL3_EV_vs_WT_F09.11384.11384.4 999 2/144 C.GSGC[160.03]GGC[160.03]GSSC[160.03]GGC[160.03]GSGC[160.03]GGC[160.03]GSGR[166.11].G sp|Q701N4|KRA52_HUMAN 1 2320.743 0.11 130909 11384 4 2320.746059 581.193 Keratin-associated protein 5-2 OS=Homo sapiens OX=9606 GN=KRTAP5-2 PE=1 SV=1 7.78 2300.7 - 744637 - - - 1.3147 - 0.188 0.807 - 0.5 1 1 0 0.0031 25 0 0 0 8.56E+06 8.04E+07 - - - 5.7176 0.9999 221125_WJC_METTL3_EV_vs_WT_F09.11388.11388.3 3.28E-10 15/60 K.IFVGGIK[136.11]EDTEEHHLR[166.11].D "sp|Q32P51|RA1L2_HUMAN,sp|P09651|ROA1_HUMAN,sp|P22626|ROA2_HUMAN,tr|A0A7I2YQN4|A0A7I2YQN4_HUMAN,tr|A0A7I2YQX9|A0A7I2YQX9_HUMAN,tr|A0A7I2V4N0|A0A7I2V4N0_HUMAN,tr|A0A024RA28|A0A024RA28_HUMAN,tr|A0A7I2V4N1|A0A7I2V4N1_HUMAN,tr|A0A7I2V4I6|A0A7I2V4I6_HUMAN,tr|F8VZ49|F8VZ49_HUMAN,tr|A0A7I2V3R8|A0A7I2V3R8_HUMAN,tr|A0A087WUI2|A0A087WUI2_HUMAN,tr|A0A7I2V4S4|A0A7I2V4S4_HUMAN,tr|F8VTQ5|F8VTQ5_HUMAN,tr|F8W6I7|F8W6I7_HUMAN,tr|A0A7I2V2L6|A0A7I2V2L6_HUMAN,tr|A0A7I2V323|A0A7I2V323_HUMAN,tr|A0A7I2V3W0|A0A7I2V3W0_HUMAN,tr|A0A7I2V5U9|A0A7I2V5U9_HUMAN,tr|A0A2R8Y4L2|A0A2R8Y4L2_HUMAN,tr|A0A7I2V3P1|A0A7I2V3P1_HUMAN,tr|A0A7I2V3P7|A0A7I2V3P7_HUMAN" 22 1896.9813 1.37 130911 11388 3 1896.976462 633.3344 Heterogeneous nuclear ribonucleoprotein A1-like 2 OS=Homo sapiens OX=9606 GN=HNRNPA1L2 PE=2 SV=2 5.36 2301.1 - 596448 - - - -2.5404 - 3.186 0.623 - 298.6 1 2 1 -0.0048 16 0 0 0 3.46E+07 2.53E+07 - - - 8.4577 0.9999 221125_WJC_METTL3_EV_vs_WT_F09.11396.11396.3 4.79E-05 16/52 K.DTSIQEVVSRPSSK.R "sp|Q8IWC1|MA7D3_HUMAN,tr|A0A0A0MRP0|A0A0A0MRP0_HUMAN" 2 1531.7842 1.28 130916 11396 3 1531.780935 511.602 MAP7 domain-containing protein 3 OS=Homo sapiens OX=9606 GN=MAP7D3 PE=1 SV=2 6.07 2302.1 - 666662 - - - -2.1322 - 2.682 0.48 - 383.5 1 2 0 -0.0033 14 0 0 0 1.05E+07 8.17E+06 - - - 6.5124 1 221125_WJC_METTL3_EV_vs_WT_F09.11397.11397.3 0.000422 15/44 R.DNIQGITK[136.11]PAIR[166.11].R sp|P62805|H4_HUMAN 1 1342.7688 1.34 130917 11397 3 1342.768008 448.5969 Histone H4 OS=Homo sapiens OX=9606 GN=H4C1 PE=1 SV=2 8.75 2302.3 - 718705 - - - -0.5667 - 2.604 0.431 - 394.6 1 2 0 -0.0008 12 0 0 0 2.25E+07 1.68E+07 - - - 5.9978 1 221125_WJC_METTL3_EV_vs_WT_F09.11405.11405.3 2.25E-08 21/92 R.APQAGAHTPLTPQPGLAPQQQSPK.Q sp|O15063|GRRE1_HUMAN 1 2419.2608 3.05 130923 11405 3 2419.255511 807.4275 Granule associated Rac and RHOG effector protein 1 OS=Homo sapiens OX=9606 GN=GARRE1 PE=1 SV=2 8.8 2303.3 - 495851 - - - -2.1891 - 3.338 0.611 - 339.6 1 2 0 -0.0053 24 0 0 0 1.15E+07 3.79E+06 - - - 8.1502 0.997 221125_WJC_METTL3_EV_vs_WT_F09.11420.11420.3 4.58E-05 15/56 L.SSGFSLEDPQTHSNR[166.11].L sp|P08238|HS90B_HUMAN 1 1670.7524 1.13 130934 11420 3 1670.752189 557.9247 Heat shock protein HSP 90-beta OS=Homo sapiens OX=9606 GN=HSP90AB1 PE=1 SV=4 5.3 2305.2 - 523463 - - - -0.1245 - 2.767 0.48 - 304.1 1 1 0 -0.0002 15 0 0 0 1.99E+07 1.76E+07 - - - 6.5472 0.993 221125_WJC_METTL3_EV_vs_WT_F09.11428.11428.3 8.05E-10 20/80 F.ASSLVSGLNSSASEPAK[136.11]EPAK[136.11].K "sp|Q86U44|MTA70_HUMAN,tr|F5H6D8|F5H6D8_HUMAN,tr|H0YFV6|H0YFV6_HUMAN,tr|B4DTN4|B4DTN4_HUMAN" 4 2045.0612 0 130940 11428 3 2045.05817 682.6943 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 6.19 2306.2 - 1.17E+06 - - - -1.464 - 3.312 0.592 - 416.2 1 1 1 -0.003 21 0 0 0 1.55E+07 3.83E+09 - - - 8.0105 0.9993 221125_WJC_METTL3_EV_vs_WT_F09.11432.11432.3 0.122 Aug-92 R.APQAGAHTPLTPQPGLAPQQQSPK[136.11].Q sp|O15063|GRRE1_HUMAN 1 2427.275 3.05 130944 11432 3 2427.268526 810.0989 Granule associated Rac and RHOG effector protein 1 OS=Homo sapiens OX=9606 GN=GARRE1 PE=1 SV=2 8.8 2306.8 - 191061 - - - -2.6701 - 1.665 0.422 - 40.2 1 2 0 -0.0065 24 0 0 0 1.15E+07 3.79E+06 - - - 4.4272 0.9808 221125_WJC_METTL3_EV_vs_WT_F09.11433.11433.4 0.117 Jun-96 K.ELFQTPVC[160.03]TDKPTTHEK.T sp|P46013|KI67_HUMAN 1 2029.9779 0.9 130945 11433 4 2029.97688 508.5017 Proliferation marker protein Ki-67 OS=Homo sapiens OX=9606 GN=MKI67 PE=1 SV=2 5.45 2306.9 - 128504 - - - -0.4985 - 1.258 0.188 - 21 1 2 0 -0.001 17 0 0 0 3.84E+06 4.26E+06 - - - 0.9418 0.9999 221125_WJC_METTL3_EV_vs_WT_F09.11436.11436.4 1.91E-05 14/90 K.GAVLPQEISQVNQHHK.S "sp|Q8IZH2|XRN1_HUMAN,tr|H7C5E4|H7C5E4_HUMAN" 2 1783.9329 1.43 130946 11436 4 1783.931294 446.9905 5'-3' exoribonuclease 1 OS=Homo sapiens OX=9606 GN=XRN1 PE=1 SV=1 6.92 2307.3 - 726665 - - - -0.9171 - 2.417 0.459 - 175 1 2 0 -0.0016 16 0 0 0 5.21E+07 3.65E+07 - - - 3.5316 0.997 221125_WJC_METTL3_EV_vs_WT_F09.11437.11437.4 5.12E-07 15/90 K.GAVLPQEISQVNQHHK[136.11].S "sp|Q8IZH2|XRN1_HUMAN,tr|H7C5E4|H7C5E4_HUMAN" 2 1791.9471 1.43 130947 11437 4 1791.941848 448.9941 5'-3' exoribonuclease 1 OS=Homo sapiens OX=9606 GN=XRN1 PE=1 SV=1 6.92 2307.4 - 737684 - - - -2.9476 - 2.659 0.284 - 174 1 2 0 -0.0053 16 0 0 0 5.21E+07 3.65E+07 - - - 2.041 0.9999 221125_WJC_METTL3_EV_vs_WT_F09.11438.11438.3 6.43E-06 14/60 K.GAVLPQEISQVNQHHK.S "sp|Q8IZH2|XRN1_HUMAN,tr|H7C5E4|H7C5E4_HUMAN" 2 1783.9329 1.41 130948 11438 3 1783.929822 595.6516 5'-3' exoribonuclease 1 OS=Homo sapiens OX=9606 GN=XRN1 PE=1 SV=1 6.92 2307.5 - 491013 - - - -1.7422 - 2.567 0.444 - 216.5 1 2 0 -0.0031 16 0 0 0 3.10E+07 2.20E+07 - - - 5.9082 0.9995 221125_WJC_METTL3_EV_vs_WT_F09.11442.11442.4 0.00651 11/120 K.ASPPITHHSIVNGQSSVLSAR.R "sp|O15409|FOXP2_HUMAN,tr|Q0PRL4|Q0PRL4_HUMAN,tr|Q8N6B5|Q8N6B5_HUMAN,tr|A0A0U1RQE0|A0A0U1RQE0_HUMAN,tr|A0A0U1RQR8|A0A0U1RQR8_HUMAN,tr|A8MUV4|A8MUV4_HUMAN,tr|A0A0U1RQM2|A0A0U1RQM2_HUMAN,tr|A0A0U1RQY3|A0A0U1RQY3_HUMAN,tr|A0A0U1RQE6|A0A0U1RQE6_HUMAN" 9 2157.1291 4.98 130950 11442 4 2157.127274 540.2895 Forkhead box protein P2 OS=Homo sapiens OX=9606 GN=FOXP2 PE=1 SV=2 9.81 2308.1 - 388765 - - - -0.8298 - 2.229 0.33 - 70.1 1 2 0 -0.0018 21 0 0 0 8.17E+06 1.64E+06 - - - 2.3628 0.9999 221125_WJC_METTL3_EV_vs_WT_F09.11443.11443.3 0.00559 16/60 K.GAVLPQEISQVNQHHK[136.11].S "sp|Q8IZH2|XRN1_HUMAN,tr|H7C5E4|H7C5E4_HUMAN" 2 1791.9471 1.41 130951 11443 3 1791.947492 598.323 5'-3' exoribonuclease 1 OS=Homo sapiens OX=9606 GN=XRN1 PE=1 SV=1 6.92 2308.2 - 463492 - - - 0.202 - 2.667 0.433 - 277.9 1 2 0 0.0004 16 0 0 0 3.10E+07 2.20E+07 - - - 5.8844 0.9991 221125_WJC_METTL3_EV_vs_WT_F09.11448.11448.4 0.000252 Nov-96 K.ELFQTPVC[160.03]TDK[136.11]PTTHEK[136.11].T sp|P46013|KI67_HUMAN 1 2046.0063 1.37 130954 11448 4 2045.998802 512.5088 Proliferation marker protein Ki-67 OS=Homo sapiens OX=9606 GN=MKI67 PE=1 SV=2 5.45 2308.8 - 209321 - - - -3.6608 - 1.979 0.393 - 94.7 1 2 0 -0.0075 17 0 0 0 4.98E+06 3.64E+06 - - - 2.8816 1 221125_WJC_METTL3_EV_vs_WT_F09.11455.11455.3 4.37E-10 16/88 R.LLEGEDAHLSSQQASGQSYSSRE.V sp|P08779|K1C16_HUMAN 1 2478.1259 999 130959 11455 3 2478.129581 827.0492 "Keratin, type I cytoskeletal 16 OS=Homo sapiens OX=9606 GN=KRT16 PE=1 SV=4" 4.6 2309.8 - 237383 - - - 1.4898 - 3.313 0.698 - 214.3 1 1 0 0.0037 23 0 0 0 8.76E+06 0.00E+00 - - - 9.1311 0.9975 221125_WJC_METTL3_EV_vs_WT_F09.11466.11466.3 1.02E-07 18/56 L.SSGFSLEDPQTHSNR.L sp|P08238|HS90B_HUMAN 1 1660.7441 1.13 130966 11466 3 1660.745319 554.5887 Heat shock protein HSP 90-beta OS=Homo sapiens OX=9606 GN=HSP90AB1 PE=1 SV=4 5.3 2311.4 - 708135 - - - 0.7178 - 3.374 0.455 - 389.6 1 1 0 0.0012 15 0 0 0 1.99E+07 1.76E+07 - - - 6.7857 0.8974 221125_WJC_METTL3_EV_vs_WT_F09.11474.11474.4 0.000302 14/120 F.ASSLVSGLNSSASEPAK[136.11]EPAK[136.11].K "sp|Q86U44|MTA70_HUMAN,tr|F5H6D8|F5H6D8_HUMAN,tr|H0YFV6|H0YFV6_HUMAN,tr|B4DTN4|B4DTN4_HUMAN" 4 2045.0612 0.09 130972 11474 4 2045.062463 512.2726 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 6.19 2312.4 - 251670 - - - 0.6352 - 2.699 0.363 - 129 1 1 1 0.0013 21 0 0 0 2.75E+06 3.19E+07 - - - 2.7135 0.9999 221125_WJC_METTL3_EV_vs_WT_F09.11481.11481.4 7.71E-06 16/108 K.TK[136.11]YPTQSGK[136.11]PPLLVSAPSK[136.11].S "sp|Q9GZR7|DDX24_HUMAN,tr|A0A087WXU8|A0A087WXU8_HUMAN,tr|F5GYL3|F5GYL3_HUMAN,tr|G3V529|G3V529_HUMAN" 4 2022.1576 0.22 130977 11481 4 2022.158076 506.5467 ATP-dependent RNA helicase DDX24 OS=Homo sapiens OX=9606 GN=DDX24 PE=1 SV=1 10 2313.3 - 504122 - - - 0.2468 - 2.858 0.544 - 167.5 1 2 1 0.0005 19 0 0 0 3.30E+06 1.50E+07 - - - 4.3161 0.9998 221125_WJC_METTL3_EV_vs_WT_F09.11482.11482.4 5.31E-05 15/108 K.TKYPTQSGKPPLLVSAPSK.S "sp|Q9GZR7|DDX24_HUMAN,tr|A0A087WXU8|A0A087WXU8_HUMAN,tr|F5GYL3|F5GYL3_HUMAN,tr|G3V529|G3V529_HUMAN" 4 1998.115 0.32 130978 11482 4 1998.114307 500.536 ATP-dependent RNA helicase DDX24 OS=Homo sapiens OX=9606 GN=DDX24 PE=1 SV=1 10 2313.5 - 390908 - - - -0.3353 - 2.968 0.461 - 161 1 2 1 -0.0007 19 0 0 0 3.30E+06 1.04E+07 - - - 3.6064 0.9999 221125_WJC_METTL3_EV_vs_WT_F09.11483.11483.3 6.18E-06 17/108 R.AAPRPAPVAQPPAAAPPSAVGSSAAAPR.Q "sp|Q5T1J5|CHCH9_HUMAN,sp|Q9Y6H1|CHCH2_HUMAN" 2 2532.3561 3.29 130979 11483 3 2532.349662 845.126 "Putative coiled-coil-helix-coiled-coil-helix domain-containing protein CHCHD2P9, mitochondrial OS=Homo sapiens OX=9606 GN=CHCHD2P9 PE=5 SV=1" 12 2313.6 - 266434 - - - -2.5439 - 2.864 0.449 - 193.1 1 2 0 -0.0064 28 0 0 0 3.68E+07 1.12E+07 - - - 5.9649 1 221125_WJC_METTL3_EV_vs_WT_F09.11485.11485.3 2.89E-08 Nov-88 R.YQEAAPNVANNTGPHAASC[160.03]FGAK.K "sp|O60716|CTND1_HUMAN,tr|A0A669KB62|A0A669KB62_HUMAN,tr|A0A804HJM1|A0A804HJM1_HUMAN,tr|A0A804HK15|A0A804HK15_HUMAN,tr|A0A669KB05|A0A669KB05_HUMAN,tr|C9JZR2|C9JZR2_HUMAN,tr|H0YC95|H0YC95_HUMAN,tr|A0A804HIL4|A0A804HIL4_HUMAN" 8 2374.076 2.25 130981 11485 3 2374.081382 792.366 Catenin delta-1 OS=Homo sapiens OX=9606 GN=CTNND1 PE=1 SV=1 6.74 2313.9 - 137504 - - - 2.2489 - 2.507 0.626 - 102.3 1 2 0 0.0053 23 0 0 0 3.32E+06 1.47E+06 - - - 7.6739 0.9998 221125_WJC_METTL3_EV_vs_WT_F09.11486.11486.3 0.000413 Oct-72 K.TKYPTQSGKPPLLVSAPSK.S "sp|Q9GZR7|DDX24_HUMAN,tr|A0A087WXU8|A0A087WXU8_HUMAN,tr|F5GYL3|F5GYL3_HUMAN,tr|G3V529|G3V529_HUMAN" 4 1998.115 0.6 130982 11486 3 1998.117744 667.0456 ATP-dependent RNA helicase DDX24 OS=Homo sapiens OX=9606 GN=DDX24 PE=1 SV=1 10 2314 - 96287.5 - - - 1.3848 - 2.292 0.504 - 115.5 1 2 1 0.0028 19 0 0 0 1.42E+06 2.35E+06 - - - 6.1961 1 221125_WJC_METTL3_EV_vs_WT_F09.11491.11491.2 2.59E-07 21/40 F.ASSLVSGLNSSASEPAK[136.11]EPAK[136.11].K "sp|Q86U44|MTA70_HUMAN,tr|F5H6D8|F5H6D8_HUMAN,tr|H0YFV6|H0YFV6_HUMAN,tr|B4DTN4|B4DTN4_HUMAN" 4 2045.0612 0.001 130985 11491 2 2045.057965 1023.5379 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 6.19 2314.7 - 916567 - - - -1.5643 - 4.139 0.645 - 1028.7 1 1 1 -0.0032 21 0 0 0 0.00E+00 5.70E+07 - - - 7.2962 1 221125_WJC_METTL3_EV_vs_WT_F09.11492.11492.3 9.60E-09 15/84 R.ATSEVPGSQASPNPVPGDGLHR.A sp|Q96GM8|TOE1_HUMAN 1 2172.056 0.88 130986 11492 3 2172.055325 725.0259 Target of EGR1 protein 1 OS=Homo sapiens OX=9606 GN=TOE1 PE=1 SV=1 5.32 2314.8 - 486373 - - - -0.2919 - 2.87 0.53 - 131.9 1 2 0 -0.0006 22 0 0 0 3.06E+07 3.49E+07 - - - 6.9484 1 221125_WJC_METTL3_EV_vs_WT_F09.11497.11497.3 3.07E-08 19/84 R.ATSEVPGSQASPNPVPGDGLHR[166.11].A sp|Q96GM8|TOE1_HUMAN 1 2182.0642 0.88 130989 11497 3 2182.061728 728.362 Target of EGR1 protein 1 OS=Homo sapiens OX=9606 GN=TOE1 PE=1 SV=1 5.32 2315.4 - 1.18E+06 - - - -1.1462 - 3.628 0.604 - 239.3 1 2 0 -0.0025 22 0 0 0 3.07E+07 3.49E+07 - - - 8.3286 0.9998 221125_WJC_METTL3_EV_vs_WT_F09.11500.11500.4 1.20E-05 Oct-72 K.KIHEEFSEHALLR.K "sp|Q9Y2L1|RRP44_HUMAN,tr|G3V1J5|G3V1J5_HUMAN" 2 1607.842 2.03 130992 11500 4 1607.836901 402.9678 Exosome complex exonuclease RRP44 OS=Homo sapiens OX=9606 GN=DIS3 PE=1 SV=2 6.02 2315.8 - 172381 - - - -3.1651 - 2.085 0.458 - 114.7 1 2 0 -0.0051 13 0 0 0 3.16E+06 1.56E+06 - - - 3.4835 0.9657 221125_WJC_METTL3_EV_vs_WT_F09.11506.11506.2 0.116 16-Aug R.K[136.11]IELFGR[166.11]PH.N sp|Q86U44|MTA70_HUMAN 1 1113.6414 0.001 130996 11506 2 1113.640187 557.828 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 8.75 2316.6 - 911362 - - - -1.074 - 1.94 0.286 - 236.2 1 1 0 -0.0012 9 0 0 0 0.00E+00 2.62E+07 - - - 3.0702 0.9995 221125_WJC_METTL3_EV_vs_WT_F09.11508.11508.4 0.000125 13/96 R.AHTVVPLDDATQEYKEK.L "sp|Q9HCM9|TRI39_HUMAN,tr|A0A0G2JKY0|A0A0G2JKY0_HUMAN,tr|A0A096LP39|A0A096LP39_HUMAN,tr|A0A140TA46|A0A140TA46_HUMAN,tr|A2AAZ6|A2AAZ6_HUMAN,tr|H0Y735|H0Y735_HUMAN" 6 1942.9636 2.25 130998 11508 4 1942.962852 486.7482 E3 ubiquitin-protein ligase TRIM39 OS=Homo sapiens OX=9606 GN=TRIM39 PE=1 SV=2 4.75 2316.9 - 353971 - - - -0.3963 - 2.574 0.406 - 134.1 1 2 1 -0.0008 17 0 0 0 4.38E+06 1.94E+06 - - - 3.0879 0.9999 221125_WJC_METTL3_EV_vs_WT_F09.11509.11509.3 6.67E-08 17/64 R.AHTVVPLDDATQEYKEK.L "sp|Q9HCM9|TRI39_HUMAN,tr|A0A0G2JKY0|A0A0G2JKY0_HUMAN,tr|A0A096LP39|A0A096LP39_HUMAN,tr|A0A140TA46|A0A140TA46_HUMAN,tr|A2AAZ6|A2AAZ6_HUMAN,tr|H0Y735|H0Y735_HUMAN" 6 1942.9636 3.27 130999 11509 3 1942.960915 648.6618 E3 ubiquitin-protein ligase TRIM39 OS=Homo sapiens OX=9606 GN=TRIM39 PE=1 SV=2 4.75 2317 - 275547 - - - -1.3932 - 3.033 0.553 - 345 1 2 1 -0.0027 17 0 0 0 3.20E+06 9.78E+05 - - - 7.5077 1 221125_WJC_METTL3_EV_vs_WT_F09.11520.11520.3 5.53E-06 13/80 K.GAQVNAVNQNGC[160.03]TPLHYAASK.N "sp|O75832|PSD10_HUMAN,tr|B1AJY7|B1AJY7_HUMAN" 2 2199.0491 1.2 131006 11520 3 2199.045652 734.0236 26S proteasome non-ATPase regulatory subunit 10 OS=Homo sapiens OX=9606 GN=PSMD10 PE=1 SV=1 8.21 2318.4 - 448182 - - - -1.568 - 2.443 0.541 - 145.8 1 2 0 -0.0034 21 0 0 0 2.04E+07 1.70E+07 - - - 6.7121 0.9999 221125_WJC_METTL3_EV_vs_WT_F09.11521.11521.3 2.67E-07 15/80 K.GAQVNAVNQNGC[160.03]TPLHYAASK[136.11].N "sp|O75832|PSD10_HUMAN,tr|B1AJY7|B1AJY7_HUMAN" 2 2207.0633 1.2 131007 11521 3 2207.070523 736.695 26S proteasome non-ATPase regulatory subunit 10 OS=Homo sapiens OX=9606 GN=PSMD10 PE=1 SV=1 8.21 2318.5 - 401375 - - - 3.2727 - 2.597 0.52 - 112.8 1 2 0 0.0072 21 0 0 0 2.04E+07 1.70E+07 - - - 6.6235 0.9994 221125_WJC_METTL3_EV_vs_WT_F09.11522.11522.3 3.24E-05 Sep-64 R.AHTVVPLDDATQEYK[136.11]EK[136.11].L "sp|Q9HCM9|TRI39_HUMAN,tr|A0A0G2JKY0|A0A0G2JKY0_HUMAN,tr|A0A096LP39|A0A096LP39_HUMAN,tr|A0A140TA46|A0A140TA46_HUMAN,tr|A2AAZ6|A2AAZ6_HUMAN,tr|H0Y735|H0Y735_HUMAN" 6 1958.992 3.27 131008 11522 3 1958.988281 654.0046 E3 ubiquitin-protein ligase TRIM39 OS=Homo sapiens OX=9606 GN=TRIM39 PE=1 SV=2 4.75 2318.6 - 195592 - - - -1.9097 - 1.986 0.472 - 89 1 2 1 -0.0037 17 0 0 0 3.20E+06 9.78E+05 - - - 5.5346 0.9975 221125_WJC_METTL3_EV_vs_WT_F09.11529.11529.3 0.000381 Oct-64 K.HTPADVQLIGTDSQGNK[136.11].F sp|P42684|ABL2_HUMAN 1 1787.8893 2.15 131013 11529 3 1787.883811 596.9704 Tyrosine-protein kinase ABL2 OS=Homo sapiens OX=9606 GN=ABL2 PE=1 SV=1 5.21 2319.6 - 250646 - - - -3.093 - 2.28 0.273 - 102.9 1 2 0 -0.0055 17 0 0 0 5.32E+06 2.48E+06 - - - 3.6643 1 221125_WJC_METTL3_EV_vs_WT_F09.11534.11534.3 1.41E-07 Oct-88 R.QPPPAPPEQADGNAPGPQPPPVR.L sp|Q12948|FOXC1_HUMAN 1 2313.1502 8.19 131016 11534 3 2313.150855 772.0573 Forkhead box protein C1 OS=Homo sapiens OX=9606 GN=FOXC1 PE=1 SV=3 4.37 2320.2 - 253868 - - - 0.2858 - 2.098 0.516 - 71.6 1 2 0 0.0007 23 0 0 0 7.90E+06 9.64E+05 - - - 6.031 0.9999 221125_WJC_METTL3_EV_vs_WT_F09.11544.11544.3 3.19E-06 14/48 R.K[136.11]TEELEEESFPER[166.11].S "sp|Q9Y2W1|TR150_HUMAN,tr|A0A3B3ITZ9|A0A3B3ITZ9_HUMAN" 2 1639.7696 3.06 131022 11544 3 1639.770719 547.5971 Thyroid hormone receptor-associated protein 3 OS=Homo sapiens OX=9606 GN=THRAP3 PE=1 SV=2 4.21 2321.5 - 357411 - - - 0.6727 - 2.453 0.36 - 306.5 1 2 0 0.0011 13 0 0 0 5.69E+07 1.86E+07 - - - 4.9862 1 221125_WJC_METTL3_EV_vs_WT_F09.11548.11548.3 4.13E-09 18/76 K.GHAYSVTGAEEVESNGSLQK.L sp|P17655|CAN2_HUMAN 1 2061.9603 999 131024 11548 3 2061.958463 688.3274 Calpain-2 catalytic subunit OS=Homo sapiens OX=9606 GN=CAPN2 PE=1 SV=6 4.75 2322 - 372647 - - - -0.904 - 3.89 0.636 - 482 1 2 0 -0.0019 20 0 0 0 4.40E+06 0.00E+00 - - - 8.9258 1 221125_WJC_METTL3_EV_vs_WT_F09.11549.11549.2 3.63E-11 17/30 V.SGLNSSASEPAK[136.11]EPAK[136.11].K "sp|Q86U44|MTA70_HUMAN,tr|F5H6D8|F5H6D8_HUMAN,tr|H0YFV6|H0YFV6_HUMAN,tr|B4DTN4|B4DTN4_HUMAN" 4 1587.8075 0.001 131025 11549 2 1587.808058 794.911 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 5.86 2322.2 - 249328 - - - 0.342 - 3.338 0.575 - 838.7 1 1 1 0.0005 16 0 0 0 0.00E+00 9.58E+06 - - - 6.2512 0.9999 221125_WJC_METTL3_EV_vs_WT_F09.11555.11555.3 1.04E-08 16/48 R.TNEKVELQELNDR.F "sp|P08670|VIME_HUMAN,sp|P17661|DESM_HUMAN,tr|B0YJC4|B0YJC4_HUMAN,tr|A0A1B0GTT5|A0A1B0GTT5_HUMAN" 4 1586.79 1.98 131029 11555 3 1586.788574 529.9373 Vimentin OS=Homo sapiens OX=9606 GN=VIM PE=1 SV=4 4.41 2322.9 - 585443 - - - -0.9075 - 3.03 0.526 - 520.1 1 2 1 -0.0014 13 0 0 0 2.30E+07 1.16E+07 - - - 7.4096 1 221125_WJC_METTL3_EV_vs_WT_F09.11563.11563.3 0.00842 15/48 R.KTEELEEESFPER.S "sp|Q9Y2W1|TR150_HUMAN,tr|A0A3B3ITZ9|A0A3B3ITZ9_HUMAN" 2 1621.7471 3.06 131033 11563 3 1621.746805 541.5897 Thyroid hormone receptor-associated protein 3 OS=Homo sapiens OX=9606 GN=THRAP3 PE=1 SV=2 4.21 2324 - 1.57E+06 - - - -0.2103 - 2.684 0.48 - 347.2 1 2 0 -0.0003 13 0 0 0 5.92E+07 1.94E+07 - - - 6.5683 0.9999 221125_WJC_METTL3_EV_vs_WT_F09.11565.11565.2 1.31E-05 24-Oct R.KTEELEEESFPER.S "sp|Q9Y2W1|TR150_HUMAN,tr|A0A3B3ITZ9|A0A3B3ITZ9_HUMAN" 2 1621.7471 9.67 131035 11565 2 1621.747727 811.8808 Thyroid hormone receptor-associated protein 3 OS=Homo sapiens OX=9606 GN=THRAP3 PE=1 SV=2 4.21 2324.3 - 89724.9 - - - 0.3583 - 2.365 0.602 - 290.1 1 2 0 0.0006 13 0 0 0 2.96E+06 3.06E+05 - - - 5.6964 0.9986 221125_WJC_METTL3_EV_vs_WT_F09.11568.11568.3 0.0128 Nov-36 R.TKYETELNLR.M sp|P02533|K1C14_HUMAN 1 1265.6616 999 131036 11568 3 1265.660334 422.8945 "Keratin, type I cytoskeletal 14 OS=Homo sapiens OX=9606 GN=KRT14 PE=1 SV=4" 5.81 2324.7 - 458236 - - - -0.9734 - 2.086 0.315 - 284.2 1 2 1 -0.0012 10 0 0 0 1.04E+07 0.00E+00 - - - 4.1988 0.9998 221125_WJC_METTL3_EV_vs_WT_F09.11576.11576.4 0.00692 10/108 R.GLLQDDAHPTLVTYADHSK[136.11].L "sp|Q86U44|MTA70_HUMAN,tr|F5H6D8|F5H6D8_HUMAN,tr|H0YFV6|H0YFV6_HUMAN,tr|B4DTN4|B4DTN4_HUMAN" 4 2088.0367 0.06 131042 11576 4 2088.03911 523.0165 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 5.13 2325.7 - 1.75E+06 - - - 1.1384 - 2.086 0.374 - 109.3 1 2 0 0.0024 19 0 0 0 1.78E+06 2.95E+07 - - - 2.7294 0.9997 221125_WJC_METTL3_EV_vs_WT_F09.11577.11577.3 0.000177 Oct-48 R.TNEK[136.11]VELQELNDR[166.11].F "sp|P08670|VIME_HUMAN,sp|P17661|DESM_HUMAN,tr|B0YJC4|B0YJC4_HUMAN,tr|A0A1B0GTT5|A0A1B0GTT5_HUMAN" 4 1604.8125 2 131043 11577 3 1604.814303 535.9448 Vimentin OS=Homo sapiens OX=9606 GN=VIM PE=1 SV=4 4.41 2325.8 - 731471 - - - 1.1335 - 2.209 0.445 - 110 1 2 1 0.0018 13 0 0 0 2.30E+07 1.15E+07 - - - 5.6496 1 221125_WJC_METTL3_EV_vs_WT_F09.11578.11578.4 1.65E-06 16/102 R.RTPQPVTIKPPPPEVVSR.G sp|O15234|CASC3_HUMAN 1 1997.1422 1.6 131044 11578 4 1997.145159 500.2928 Protein CASC3 OS=Homo sapiens OX=9606 GN=CASC3 PE=1 SV=2 10.84 2326 - 214252 - - - 1.4841 - 3.153 0.534 - 172.2 1 2 0 0.003 18 0 0 0 1.12E+07 7.00E+06 - - - 4.2665 0.977 221125_WJC_METTL3_EV_vs_WT_F09.11579.11579.3 0.000425 Oct-72 K.DAGTDKNPPETAPVEVVEK.K sp|Q96T58|MINT_HUMAN 1 1994.9797 3.17 131045 11579 3 1994.989822 666.0005 Msx2-interacting protein OS=Homo sapiens OX=9606 GN=SPEN PE=1 SV=1 4.18 2326.1 - 153135 - - - 5.0908 - 1.818 0.381 - 90 1 2 1 0.0102 19 0 0 0 3.01E+07 9.49E+06 - - - 4.2535 0.9886 221125_WJC_METTL3_EV_vs_WT_F09.11583.11583.2 0.422 16-May R.QTVAVGVIK[136.11].N "sp|Q05639|EF1A2_HUMAN,sp|P68104|EF1A1_HUMAN,sp|Q5VTE0|EF1A3_HUMAN,tr|A0A7I2V659|A0A7I2V659_HUMAN,tr|A0A2U3TZH3|A0A2U3TZH3_HUMAN,tr|A0A087WVQ9|A0A087WVQ9_HUMAN" 6 921.5739 1.32 131046 11583 2 921.574773 461.7942 Elongation factor 1-alpha 2 OS=Homo sapiens OX=9606 GN=EEF1A2 PE=1 SV=1 8.75 2326.6 - 198446 - - - 0.9831 - 1.088 0.222 - 71.9 3 2 0 0.0009 9 0 0 0 4.94E+06 3.75E+06 - - - 0.7113 0.9992 221125_WJC_METTL3_EV_vs_WT_F09.11584.11584.2 0.00251 14-Jul K.VIPELNGK[136.11].L "sp|P04406|G3P_HUMAN,tr|E7EUT5|E7EUT5_HUMAN" 2 876.516 1.03 131047 11584 2 876.517145 439.2653 Glyceraldehyde-3-phosphate dehydrogenase OS=Homo sapiens OX=9606 GN=GAPDH PE=1 SV=3 5.97 2326.8 - 204806 - - - 1.2858 - 1.308 0.422 - 144 1 2 0 0.0011 8 0 0 0 4.90E+06 4.76E+06 - - - 2.9673 1 221125_WJC_METTL3_EV_vs_WT_F09.11589.11589.4 8.09E-09 19/162 R.AAPRPAPVAQPPAAAPPSAVGSSAAAPR.Q "sp|Q5T1J5|CHCH9_HUMAN,sp|Q9Y6H1|CHCH2_HUMAN" 2 2532.3561 4.13 131050 11589 4 2532.361368 634.0963 "Putative coiled-coil-helix-coiled-coil-helix domain-containing protein CHCHD2P9, mitochondrial OS=Homo sapiens OX=9606 GN=CHCHD2P9 PE=5 SV=1" 12 2327.4 - 183867 - - - 2.0787 - 3.702 0.581 - 113.4 1 2 0 0.0053 28 0 0 0 9.77E+06 2.36E+06 - - - 4.6879 0.9972 221125_WJC_METTL3_EV_vs_WT_F09.11590.11590.2 0.0126 14-Jul K.VIPELNGK.L "sp|P04406|G3P_HUMAN,tr|E7EUT5|E7EUT5_HUMAN" 2 868.5018 1.03 131051 11590 2 868.503637 435.2582 Glyceraldehyde-3-phosphate dehydrogenase OS=Homo sapiens OX=9606 GN=GAPDH PE=1 SV=3 5.97 2327.6 - 236633 - - - 2.0944 - 1.194 0.365 - 156.3 1 2 0 0.0018 8 0 0 0 4.90E+06 4.76E+06 - - - 2.2711 0.971 221125_WJC_METTL3_EV_vs_WT_F09.11595.11595.3 0.252 5/108 R.AAPR[166.11]PAPVAQPPAAAPPSAVGSSAAAPR[166.11].Q "sp|Q5T1J5|CHCH9_HUMAN,sp|Q9Y6H1|CHCH2_HUMAN" 2 2552.3726 3.27 131056 11595 3 2552.372545 851.7982 "Putative coiled-coil-helix-coiled-coil-helix domain-containing protein CHCHD2P9, mitochondrial OS=Homo sapiens OX=9606 GN=CHCHD2P9 PE=5 SV=1" 12 2328.2 - 127649 - - - -0.0388 - 1.323 0.191 - 15.1 2 2 0 -0.0001 28 0 0 0 3.56E+07 1.09E+07 - - - 1.1741 0.9999 221125_WJC_METTL3_EV_vs_WT_F09.11599.11599.3 1.92E-05 Nov-76 K.HLEQQQGQLEVPEQQVGQPK.N sp|P07476|INVO_HUMAN 1 2299.1557 999 131058 11599 3 2299.16089 767.3925 Involucrin OS=Homo sapiens OX=9606 GN=IVL PE=1 SV=2 4.75 2328.8 - 66957.4 - - - 2.2691 - 2.474 0.505 - 92.4 1 2 0 0.0052 20 0 0 0 1.03E+06 0.00E+00 - - - 6.3664 1 221125_WJC_METTL3_EV_vs_WT_F09.11604.11604.3 1.85E-10 25/76 K.ASESSKPWPDATYGTGSASR.A "sp|Q9Y2W1|TR150_HUMAN,tr|A0A3B3ITZ9|A0A3B3ITZ9_HUMAN" 2 2053.9341 1.3 131061 11604 3 2053.938665 685.652 Thyroid hormone receptor-associated protein 3 OS=Homo sapiens OX=9606 GN=THRAP3 PE=1 SV=2 6.11 2329.5 - 1.57E+06 - - - 2.2167 - 4.104 0.574 - 622.6 1 2 0 0.0046 20 0 0 0 9.81E+06 7.52E+06 - - - 8.3637 1 221125_WJC_METTL3_EV_vs_WT_F09.11610.11610.3 1.10E-08 23/76 K.ASESSK[136.11]PWPDATYGTGSASR[166.11].A "sp|Q9Y2W1|TR150_HUMAN,tr|A0A3B3ITZ9|A0A3B3ITZ9_HUMAN" 2 2071.9566 2.74 131065 11610 3 2071.961132 691.6595 Thyroid hormone receptor-associated protein 3 OS=Homo sapiens OX=9606 GN=THRAP3 PE=1 SV=2 6.11 2330.3 - 1.55E+06 - - - 2.196 - 3.532 0.602 - 449.2 1 2 0 0.0045 20 0 0 0 1.03E+10 3.77E+09 - - - 8.3118 0.9999 221125_WJC_METTL3_EV_vs_WT_F09.11625.11625.3 8.49E-06 20/76 K.QSAQLTALAAQQQAAGK[136.11]EEK[136.11].S sp|Q96A49|SYAP1_HUMAN 1 2086.0989 1.09 131076 11625 3 2086.101349 696.3736 Synapse-associated protein 1 OS=Homo sapiens OX=9606 GN=SYAP1 PE=1 SV=1 6.14 2332.4 - 360019 - - - 1.1519 - 3.702 0.538 - 573.1 1 2 1 0.0024 20 0 0 0 1.27E+08 1.17E+08 - - - 7.7129 0.9991 221125_WJC_METTL3_EV_vs_WT_F09.11626.11626.4 0.000496 Dec-90 K.AADKLIQNLDANHDGR.L sp|Q96FQ6|S10AG_HUMAN 1 1749.8758 9.12 131077 11626 4 1749.88088 438.4762 Protein S100-A16 OS=Homo sapiens OX=9606 GN=S100A16 PE=1 SV=1 5.3 2332.5 - 251501 - - - 2.8973 - 1.936 0.45 - 112.7 1 2 1 0.0051 16 0 0 0 4.53E+06 4.97E+05 - - - 3.3741 0.9951 221125_WJC_METTL3_EV_vs_WT_F09.11637.11637.4 0.0151 Jul-96 R.GSGTAIKPLPSYENLKK.E sp|Q8IXW5|RPAP2_HUMAN 1 1801.9938 1.22 131086 11637 4 1801.994046 451.5057 Putative RNA polymerase II subunit B1 CTD phosphatase RPAP2 OS=Homo sapiens OX=9606 GN=RPAP2 PE=1 SV=1 9.53 2334 - 198764 - - - 0.1371 - 1.728 0.305 - 23.6 7 2 0 0.0002 17 0 0 0 5.67E+06 4.66E+06 - - - 1.4265 1 221125_WJC_METTL3_EV_vs_WT_F09.11638.11638.2 1.73E-11 14/38 K.ASESSKPWPDATYGTGSASR.A "sp|Q9Y2W1|TR150_HUMAN,tr|A0A3B3ITZ9|A0A3B3ITZ9_HUMAN" 2 2053.9341 2.8 131087 11638 2 2053.935276 1027.9743 Thyroid hormone receptor-associated protein 3 OS=Homo sapiens OX=9606 GN=THRAP3 PE=1 SV=2 6.11 2334.1 - 337677 - - - 0.5667 - 3.032 0.54 - 249.8 1 2 0 0.0012 20 0 0 0 2.39E+08 8.53E+07 - - - 5.7561 1 221125_WJC_METTL3_EV_vs_WT_F09.11645.11645.2 1.79E-11 13/38 K.ASESSK[136.11]PWPDATYGTGSASR[166.11].A "sp|Q9Y2W1|TR150_HUMAN,tr|A0A3B3ITZ9|A0A3B3ITZ9_HUMAN" 2 2071.9566 2.8 131092 11645 2 2071.95676 1036.9856 Thyroid hormone receptor-associated protein 3 OS=Homo sapiens OX=9606 GN=THRAP3 PE=1 SV=2 6.11 2335 - 292276 - - - 0.0859 - 2.864 0.698 - 218 1 2 0 0.0002 20 0 0 0 2.39E+08 8.53E+07 - - - 6.7833 0.9892 221125_WJC_METTL3_EV_vs_WT_F09.11659.11659.3 8.56E-08 20/80 F.ASSLVSGLNSSASEPAK[136.11]EPAK[136.11].K "sp|Q86U44|MTA70_HUMAN,tr|F5H6D8|F5H6D8_HUMAN,tr|H0YFV6|H0YFV6_HUMAN,tr|B4DTN4|B4DTN4_HUMAN" 4 2045.0612 0 131102 11659 3 2045.057912 682.6943 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 6.19 2336.8 - 1.05E+06 - - - -1.5902 - 3.236 0.539 - 495.9 1 1 1 -0.0033 21 0 0 0 1.55E+07 3.83E+09 - - - 7.3638 0.9974 221125_WJC_METTL3_EV_vs_WT_F09.11665.11665.4 0.00852 11/114 K.ASESSKPWPDATYGTGSASR.A "sp|Q9Y2W1|TR150_HUMAN,tr|A0A3B3ITZ9|A0A3B3ITZ9_HUMAN" 2 2053.9341 3.42 131106 11665 4 2053.927616 514.4908 Thyroid hormone receptor-associated protein 3 OS=Homo sapiens OX=9606 GN=THRAP3 PE=1 SV=2 6.11 2337.5 - 704444 - - - -3.1627 - 1.976 0.313 - 87.5 1 2 0 -0.0065 20 0 0 0 2.52E+07 7.35E+06 - - - 2.1762 0.9999 221125_WJC_METTL3_EV_vs_WT_F09.11673.11673.3 0.000243 Oct-52 K.K[136.11]GPGEVAGTVTGQK[136.11].R "sp|Q86U44|MTA70_HUMAN,tr|F5H6D8|F5H6D8_HUMAN,tr|H0YFV6|H0YFV6_HUMAN,tr|B4DTN4|B4DTN4_HUMAN" 4 1343.738 0.01 131111 11673 3 1343.735903 448.9199 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 8.59 2338.5 - 363266 - - - -1.5449 - 2.222 0.41 - 164.8 1 2 0 -0.0021 14 0 0 0 1.59E+05 1.85E+07 - - - 5.2323 1 221125_WJC_METTL3_EV_vs_WT_F09.11685.11685.3 2.41E-10 22/72 K.ASSSSASSAGALESSLDRK.F sp|Q5VT52|RPRD2_HUMAN 1 1809.8704 14.32 131117 11685 3 1809.87133 604.2974 Regulation of nuclear pre-mRNA domain-containing protein 2 OS=Homo sapiens OX=9606 GN=RPRD2 PE=1 SV=1 6.11 2340.1 - 440732 - - - 0.4868 - 4.151 0.658 - 823.3 1 2 0 0.0009 19 0 0 0 4.41E+07 3.08E+06 - - - 9.3727 0.9967 221125_WJC_METTL3_EV_vs_WT_F09.11705.11705.3 2.19E-06 Dec-72 A.SESSKPWPDATYGTGSASR.A "sp|Q9Y2W1|TR150_HUMAN,tr|A0A3B3ITZ9|A0A3B3ITZ9_HUMAN" 2 1982.897 4.37 131125 11705 3 1982.897073 661.9729 Thyroid hormone receptor-associated protein 3 OS=Homo sapiens OX=9606 GN=THRAP3 PE=1 SV=2 5.79 2342.9 - 550847 - - - 0.0373 - 2.004 0.556 - 143.4 1 1 0 0.0001 19 0 0 0 9.69E+06 2.22E+06 - - - 6.4467 0.9993 221125_WJC_METTL3_EV_vs_WT_F09.11707.11707.4 3.37E-06 15/108 K.EAEKLESEHPDQAQAILSR.L "sp|Q01082|SPTB2_HUMAN,tr|A0A087WUZ3|A0A087WUZ3_HUMAN" 2 2150.0604 1.99 131126 11707 4 2150.055207 538.5224 "Spectrin beta chain, non-erythrocytic 1 OS=Homo sapiens OX=9606 GN=SPTBN1 PE=1 SV=2" 4.57 2343.1 - 1.62E+06 - - - -2.4041 - 2.77 0.429 - 150.4 1 2 1 -0.0052 19 0 0 0 3.12E+07 1.57E+07 - - - 3.3032 0.9983 221125_WJC_METTL3_EV_vs_WT_F09.11737.11737.3 2.35E-05 Oct-64 R.KASSPSPLTIGTPESQR.K sp|Q9NPI6|DCP1A_HUMAN 1 1754.9163 3.13 131144 11737 3 1754.910541 585.9794 mRNA-decapping enzyme 1A OS=Homo sapiens OX=9606 GN=DCP1A PE=1 SV=3 8.75 2346.9 - 204741 - - - -3.2685 - 2.111 0.325 - 80.8 1 2 0 -0.0057 17 0 0 0 5.19E+06 1.66E+06 - - - 4.0494 1 221125_WJC_METTL3_EV_vs_WT_F09.11751.11751.3 5.89E-08 16/64 R.C[160.03]SAGLGALAQRPGSVSK.W "sp|Q9NXV2|KCTD5_HUMAN,tr|H3BSS5|H3BSS5_HUMAN" 2 1657.857 4.4 131151 11751 3 1657.85986 553.6263 BTB\POZ domain-containing protein KCTD5 OS=Homo sapiens OX=9606 GN=KCTD5 PE=1 SV=1 9.51 2348.7 - 641290 - - - 1.7318 - 3.733 0.588 - 461.7 1 2 0 0.0029 17 0 0 0 1.80E+07 4.08E+06 - - - 8.4225 0.8396 221125_WJC_METTL3_EV_vs_WT_F09.11752.11752.4 1.99 6/102 K.AAVHTYGIASVPNQPLK[136.11]K[136.11].Q "sp|Q9UHI6|DDX20_HUMAN,tr|A0A7P0T9T8|A0A7P0T9T8_HUMAN" 2 1909.0756 1.09 131152 11752 4 1909.079913 478.2762 Probable ATP-dependent RNA helicase DDX20 OS=Homo sapiens OX=9606 GN=DDX20 PE=1 SV=2 9.7 2348.9 - 105439 - - - 2.2424 - 1.105 0.132 - 20.1 1 2 0 0.0043 18 0 0 0 1.95E+06 1.79E+06 - - - 0.4079 0.9479 221125_WJC_METTL3_EV_vs_WT_F09.11757.11757.3 0.00247 Nov-88 R.NAAFGQSGGAGSDSNSPGNVQPN.S sp|Q9BYJ9|YTHD1_HUMAN 1 2131.9155 - 131155 11757 3 2131.91916 711.6458 YTH domain-containing family protein 1 OS=Homo sapiens OX=9606 GN=YTHDF1 PE=1 SV=1 3.8 2349.6 - 263267 - - - 1.7158 - 1.528 0.416 - 62.1 1 1 0 0.0037 23 0 0 0 - - - - - 4.1716 0.9994 221125_WJC_METTL3_EV_vs_WT_F09.11759.11759.4 1.21E-05 Oct-90 K.IFVGGIKEDTEEHHLR.D "sp|Q32P51|RA1L2_HUMAN,sp|P09651|ROA1_HUMAN,sp|P22626|ROA2_HUMAN,tr|A0A7I2YQN4|A0A7I2YQN4_HUMAN,tr|A0A7I2YQX9|A0A7I2YQX9_HUMAN,tr|A0A7I2V4N0|A0A7I2V4N0_HUMAN,tr|A0A024RA28|A0A024RA28_HUMAN,tr|A0A7I2V4N1|A0A7I2V4N1_HUMAN,tr|A0A7I2V4I6|A0A7I2V4I6_HUMAN,tr|F8VZ49|F8VZ49_HUMAN,tr|A0A7I2V3R8|A0A7I2V3R8_HUMAN,tr|A0A087WUI2|A0A087WUI2_HUMAN,tr|A0A7I2V4S4|A0A7I2V4S4_HUMAN,tr|F8VTQ5|F8VTQ5_HUMAN,tr|F8W6I7|F8W6I7_HUMAN,tr|A0A7I2V2L6|A0A7I2V2L6_HUMAN,tr|A0A7I2V323|A0A7I2V323_HUMAN,tr|A0A7I2V3W0|A0A7I2V3W0_HUMAN,tr|A0A7I2V5U9|A0A7I2V5U9_HUMAN,tr|A0A2R8Y4L2|A0A2R8Y4L2_HUMAN,tr|A0A7I2V3P1|A0A7I2V3P1_HUMAN,tr|A0A7I2V3P7|A0A7I2V3P7_HUMAN" 22 1878.9588 1.27 131157 11759 4 1878.965605 470.747 Heterogeneous nuclear ribonucleoprotein A1-like 2 OS=Homo sapiens OX=9606 GN=HNRNPA1L2 PE=2 SV=2 5.36 2349.8 - 131881 - - - 3.6158 - 2.205 0.512 - 72.5 1 2 1 0.0068 16 0 0 0 4.77E+06 3.77E+06 - - - 3.9591 1 221125_WJC_METTL3_EV_vs_WT_F09.11763.11763.3 6.46E-12 21/88 R.QPPPAPPEQADGNAPGPQPPPVR.L sp|Q12948|FOXC1_HUMAN 1 2313.1502 3.76 131159 11763 3 2313.156694 772.0573 Forkhead box protein C1 OS=Homo sapiens OX=9606 GN=FOXC1 PE=1 SV=3 4.37 2350.5 - 629902 - - - 2.81 - 3.346 0.639 - 308.2 1 2 0 0.0065 23 0 0 0 2.41E+07 6.42E+06 - - - 8.4958 1 221125_WJC_METTL3_EV_vs_WT_F09.11764.11764.3 1.40E-07 Dec-64 R.C[160.03]SAGLGALAQR[166.11]PGSVSK[136.11].W "sp|Q9NXV2|KCTD5_HUMAN,tr|H3BSS5|H3BSS5_HUMAN" 2 1675.8795 4.4 131160 11764 3 1675.881903 559.6338 BTB\POZ domain-containing protein KCTD5 OS=Homo sapiens OX=9606 GN=KCTD5 PE=1 SV=1 9.51 2350.7 - 174276 - - - 1.4583 - 2.715 0.565 - 165.2 1 2 0 0.0024 17 0 0 0 1.80E+07 4.08E+06 - - - 7.3618 1 221125_WJC_METTL3_EV_vs_WT_F09.11769.11769.3 1.76E-06 Nov-64 R.FSHQASGFQC[160.03]DLTTNNR[166.11].L sp|Q9NVV4|PAPD1_HUMAN 1 1991.8783 0.93 131163 11769 3 1991.880466 664.9667 "Poly(A) RNA polymerase, mitochondrial OS=Homo sapiens OX=9606 GN=MTPAP PE=1 SV=1" 6.74 2351.4 - 130519 - - - 1.0658 - 2.591 0.597 - 144.5 1 2 0 0.0021 17 0 0 0 2.19E+06 2.36E+06 - - - 7.6005 0.9998 221125_WJC_METTL3_EV_vs_WT_F09.11780.11780.3 0.000226 13/88 R.QPPPAPPEQADGNAPGPQPPPVR[166.11].L sp|Q12948|FOXC1_HUMAN 1 2323.1585 4.75 131170 11780 3 2323.163051 775.3934 Forkhead box protein C1 OS=Homo sapiens OX=9606 GN=FOXC1 PE=1 SV=3 4.37 2352.9 - 247320 - - - 1.9745 - 2.265 0.425 - 110.9 1 2 0 0.0046 23 0 0 0 5.40E+07 1.14E+07 - - - 5.195 0.996 221125_WJC_METTL3_EV_vs_WT_F09.11791.11791.3 0.365 Sep-48 R.KTEELEEESFPER.S "sp|Q9Y2W1|TR150_HUMAN,tr|A0A3B3ITZ9|A0A3B3ITZ9_HUMAN" 2 1621.7471 2.81 131177 11791 3 1621.752973 541.5897 Thyroid hormone receptor-associated protein 3 OS=Homo sapiens OX=9606 GN=THRAP3 PE=1 SV=2 4.21 2354.5 - 130081 - - - 3.593 - 1.947 0.292 - 106.3 1 2 0 0.0058 13 0 0 0 8.72E+07 3.11E+07 - - - 3.6004 0.9874 221125_WJC_METTL3_EV_vs_WT_F09.11810.11810.4 0.0384 10/132 R.QPPPAPPEQADGNAPGPQPPPVR.L sp|Q12948|FOXC1_HUMAN 1 2313.1502 4.26 131190 11810 4 2313.159595 579.2948 Forkhead box protein C1 OS=Homo sapiens OX=9606 GN=FOXC1 PE=1 SV=3 4.37 2357.1 - 168774 - - - 4.0642 - 1.826 0.273 - 38.3 1 2 0 0.0094 23 0 0 0 2.49E+06 5.84E+05 - - - 1.7947 0.9936 221125_WJC_METTL3_EV_vs_WT_F09.11811.11811.3 0.0462 Oct-44 R.LLASTLVHSVKK.E "sp|Q9NYF8|BCLF1_HUMAN,tr|E9PKI6|E9PKI6_HUMAN,tr|A0A1W2PQ43|A0A1W2PQ43_HUMAN,tr|E9PK91|E9PK91_HUMAN,tr|E9PJA7|E9PJA7_HUMAN,tr|E9PK09|E9PK09_HUMAN,tr|E9PQN2|E9PQN2_HUMAN" 7 1294.7973 1.7 131191 11811 3 1294.802964 432.6064 Bcl-2-associated transcription factor 1 OS=Homo sapiens OX=9606 GN=BCLAF1 PE=1 SV=2 10 2357.3 - 139245 - - - 4.3961 - 2.157 0.27 - 81.8 1 2 0 0.0057 12 0 0 0 2.44E+06 1.44E+06 - - - 3.6794 0.994 221125_WJC_METTL3_EV_vs_WT_F09.11812.11812.3 0.0162 Jul-88 K.FQPASAPAEDC[160.03]ISSSTEPK[136.11]PDPK[136.11].K sp|Q14008|CKAP5_HUMAN 1 2474.1606 1.45 131192 11812 3 2474.167596 825.7275 Cytoskeleton-associated protein 5 OS=Homo sapiens OX=9606 GN=CKAP5 PE=1 SV=3 4.32 2357.4 - 123371 - - - 2.8195 - 1.251 0.345 - 26.7 1 2 0 0.007 23 0 0 0 6.80E+06 4.69E+06 - - - 2.9098 0.9992 221125_WJC_METTL3_EV_vs_WT_F09.11817.11817.3 0.000305 Aug-88 K.FQPASAPAEDC[160.03]ISSSTEPKPDPK.K sp|Q14008|CKAP5_HUMAN 1 2458.1322 1.45 131195 11817 3 2458.138789 820.3847 Cytoskeleton-associated protein 5 OS=Homo sapiens OX=9606 GN=CKAP5 PE=1 SV=3 4.32 2358.1 - 217928 - - - 2.6724 - 1.712 0.403 - 34.2 1 2 0 0.0066 23 0 0 0 6.80E+06 4.69E+06 - - - 4.2926 0.9998 221125_WJC_METTL3_EV_vs_WT_F09.11819.11819.3 0.00127 Aug-64 R.SGDEEFKGEDELC[160.03]DSGR.Q "sp|O43823|AKAP8_HUMAN,tr|A0A7P0TBC8|A0A7P0TBC8_HUMAN,tr|A0A7P0T893|A0A7P0T893_HUMAN,tr|M0QX51|M0QX51_HUMAN" 4 1928.7694 2.82 131197 11819 3 1928.770961 643.9304 A-kinase anchor protein 8 OS=Homo sapiens OX=9606 GN=AKAP8 PE=1 SV=1 3.95 2358.4 - 65746 - - - 0.8015 - 1.664 0.578 - 84.3 1 2 1 0.0015 17 0 0 0 9.64E+05 3.42E+05 - - - 6.2702 0.7922 221125_WJC_METTL3_EV_vs_WT_F09.11820.11820.3 0.0602 May-76 R.SPLLAGGSPPQPVVPAHKDK.S "sp|Q8NFH5|NUP35_HUMAN,tr|F8WCF5|F8WCF5_HUMAN,tr|F8WEL4|F8WEL4_HUMAN,tr|C9JIY9|C9JIY9_HUMAN,tr|C9IYQ7|C9IYQ7_HUMAN" 5 1994.0949 2.63 131198 11820 3 1994.09892 665.7056 Nucleoporin NUP35 OS=Homo sapiens OX=9606 GN=NUP35 PE=1 SV=1 8.33 2358.5 - 49885.6 - - - 2.0104 - 1.273 0.185 - 22.8 1 2 1 0.004 20 0 0 0 2.87E+06 1.09E+06 - - - 1.187 0.9999 221125_WJC_METTL3_EV_vs_WT_F09.11824.11824.3 3.36E-07 Oct-44 R.LLASTLVHSVK[136.11]K[136.11].E "sp|Q9NYF8|BCLF1_HUMAN,tr|E9PKI6|E9PKI6_HUMAN,tr|A0A1W2PQ43|A0A1W2PQ43_HUMAN,tr|E9PK91|E9PK91_HUMAN,tr|E9PJA7|E9PJA7_HUMAN,tr|E9PK09|E9PK09_HUMAN,tr|E9PQN2|E9PQN2_HUMAN" 7 1310.8257 1.7 131200 11824 3 1310.829233 437.9492 Bcl-2-associated transcription factor 1 OS=Homo sapiens OX=9606 GN=BCLAF1 PE=1 SV=2 10 2359 - 155291 - - - 2.7166 - 2.143 0.601 - 126.7 1 2 0 0.0036 12 0 0 0 2.44E+06 1.44E+06 - - - 7.3523 0.9997 221125_WJC_METTL3_EV_vs_WT_F09.11825.11825.4 1.88E-05 16/114 R.SPLLAGGSPPQPVVPAHKDK.S "sp|Q8NFH5|NUP35_HUMAN,tr|F8WCF5|F8WCF5_HUMAN,tr|F8WEL4|F8WEL4_HUMAN,tr|C9JIY9|C9JIY9_HUMAN,tr|C9IYQ7|C9IYQ7_HUMAN" 5 1994.0949 2.25 131201 11825 4 1994.100933 499.531 Nucleoporin NUP35 OS=Homo sapiens OX=9606 GN=NUP35 PE=1 SV=1 8.33 2359.1 - 193027 - - - 3.0199 - 3.211 0.549 - 148.7 1 2 1 0.006 20 0 0 0 7.31E+06 3.24E+06 - - - 4.3928 0.9973 221125_WJC_METTL3_EV_vs_WT_F09.11828.11828.4 0.00165 Sep-78 K.SHLEVPLEENVNR[166.11]R[166.11].V "sp|Q96CT7|CC124_HUMAN,tr|M0R2F5|M0R2F5_HUMAN" 2 1710.8916 1.42 131204 11828 4 1710.896196 428.7302 Coiled-coil domain-containing protein 124 OS=Homo sapiens OX=9606 GN=CCDC124 PE=1 SV=1 5.47 2359.5 - 130577 - - - 2.674 - 1.82 0.296 - 70.5 1 2 0 0.0046 14 0 0 0 8.04E+06 5.66E+06 - - - 2.0191 0.9961 221125_WJC_METTL3_EV_vs_WT_F09.11829.11829.4 0.00892 Jun-96 R.TDEEGK[136.11]DVPDHAVLEMK[136.11].A "sp|Q9BUJ2|HNRL1_HUMAN,tr|A0A0A0MRA5|A0A0A0MRA5_HUMAN,tr|M0R3F1|M0R3F1_HUMAN,tr|B7Z4B8|B7Z4B8_HUMAN" 4 1927.9168 2.47 131205 11829 4 1927.922421 482.9865 Heterogeneous nuclear ribonucleoprotein U-like protein 1 OS=Homo sapiens OX=9606 GN=HNRNPUL1 PE=1 SV=2 4.29 2359.6 - 112375 - - - 2.9114 - 1.688 0.387 - 23.8 2 2 1 0.0056 17 0 0 0 9.81E+06 3.97E+06 - - - 2.5452 0.9984 221125_WJC_METTL3_EV_vs_WT_F09.11830.11830.4 0.00241 11/114 R.SPLLAGGSPPQPVVPAHK[136.11]DK[136.11].S "sp|Q8NFH5|NUP35_HUMAN,tr|F8WCF5|F8WCF5_HUMAN,tr|F8WEL4|F8WEL4_HUMAN,tr|C9JIY9|C9JIY9_HUMAN,tr|C9IYQ7|C9IYQ7_HUMAN" 5 2010.1233 2.3 131206 11830 4 2010.12841 503.5381 Nucleoporin NUP35 OS=Homo sapiens OX=9606 GN=NUP35 PE=1 SV=1 8.33 2359.7 - 110504 - - - 2.5367 - 1.934 0.393 - 48.9 1 2 1 0.0051 20 0 0 0 7.30E+06 3.17E+06 - - - 2.8658 0.9999 221125_WJC_METTL3_EV_vs_WT_F09.11831.11831.3 2.35E-06 Oct-64 R.TDEEGKDVPDHAVLEMK.A "sp|Q9BUJ2|HNRL1_HUMAN,tr|A0A0A0MRA5|A0A0A0MRA5_HUMAN,tr|M0R3F1|M0R3F1_HUMAN,tr|B7Z4B8|B7Z4B8_HUMAN" 4 1911.8884 2.09 131207 11831 3 1911.888569 638.3034 Heterogeneous nuclear ribonucleoprotein U-like protein 1 OS=Homo sapiens OX=9606 GN=HNRNPUL1 PE=1 SV=2 4.29 2359.9 - 78181.7 - - - 0.0842 - 2.332 0.571 - 127.4 1 2 1 0.0002 17 0 0 0 4.38E+06 2.10E+06 - - - 7.0451 1 221125_WJC_METTL3_EV_vs_WT_F09.11835.11835.3 3.38E-10 19/76 K.ASESSKPWPDATYGTGSASR.A "sp|Q9Y2W1|TR150_HUMAN,tr|A0A3B3ITZ9|A0A3B3ITZ9_HUMAN" 2 2053.9341 2.81 131210 11835 3 2053.940824 685.652 Thyroid hormone receptor-associated protein 3 OS=Homo sapiens OX=9606 GN=THRAP3 PE=1 SV=2 6.11 2360.5 - 538270 - - - 3.2679 - 3.294 0.624 - 287.5 1 2 0 0.0067 20 0 0 0 1.99E+07 7.09E+06 - - - 8.3872 0.9984 221125_WJC_METTL3_EV_vs_WT_F09.11838.11838.3 2.31E-06 14/60 K.AK[136.11]SDQLLSSNENFTNK[136.11].V "sp|Q15643|TRIPB_HUMAN,tr|H0YJ97|H0YJ97_HUMAN" 2 1810.9032 1.97 131213 11838 3 1810.912997 604.6417 Thyroid receptor-interacting protein 11 OS=Homo sapiens OX=9606 GN=TRIP11 PE=1 SV=3 6.11 2360.8 - 496120 - - - 5.4061 - 2.877 0.55 - 245.4 1 2 1 0.0098 16 0 0 0 2.21E+07 1.12E+07 - - - 7.3807 0.9992 221125_WJC_METTL3_EV_vs_WT_F09.11841.11841.3 0.00937 Oct-52 K.SHLEVPLEENVNRR.V "sp|Q96CT7|CC124_HUMAN,tr|M0R2F5|M0R2F5_HUMAN" 2 1690.8751 1.77 131216 11841 3 1690.879174 564.6323 Coiled-coil domain-containing protein 124 OS=Homo sapiens OX=9606 GN=CCDC124 PE=1 SV=1 5.47 2361.2 - 192999 - - - 2.4206 - 1.808 0.367 - 136.1 1 2 0 0.0041 14 0 0 0 8.22E+06 4.63E+06 - - - 4.2044 0.9997 221125_WJC_METTL3_EV_vs_WT_F09.11842.11842.4 8.35E-05 Oct-78 K.SHLEVPLEENVNRR.V "sp|Q96CT7|CC124_HUMAN,tr|M0R2F5|M0R2F5_HUMAN" 2 1690.8751 1.42 131217 11842 4 1690.879629 423.726 Coiled-coil domain-containing protein 124 OS=Homo sapiens OX=9606 GN=CCDC124 PE=1 SV=1 5.47 2361.4 - 172755 - - - 2.6897 - 1.93 0.416 - 140.6 1 2 0 0.0045 14 0 0 0 8.04E+06 5.66E+06 - - - 3.0849 0.9999 221125_WJC_METTL3_EV_vs_WT_F09.11843.11843.3 2.57E-07 Nov-76 K.AEEYTEETEEREESTTGFDK.S "sp|Q9Y2W1|TR150_HUMAN,tr|A0A3B3ITZ9|A0A3B3ITZ9_HUMAN" 2 2378.9874 7.07 131218 11843 3 2378.991519 794.0031 Thyroid hormone receptor-associated protein 3 OS=Homo sapiens OX=9606 GN=THRAP3 PE=1 SV=2 3.93 2361.5 - 112611 - - - 1.736 - 2.757 0.62 - 121.5 1 2 1 0.0041 20 0 0 0 9.50E+05 1.34E+05 - - - 7.9116 0.999 221125_WJC_METTL3_EV_vs_WT_F09.11846.11846.2 7.30E-06 Aug-38 K.SFNYSPNSSTSEVSSTSASK.A sp|Q5VT52|RPRD2_HUMAN 1 2065.9076 2.56 131221 11846 2 2065.916501 1033.9611 Regulation of nuclear pre-mRNA domain-containing protein 2 OS=Homo sapiens OX=9606 GN=RPRD2 PE=1 SV=1 5.72 2361.9 - 32548.7 - - - 4.2974 - 1.859 0.691 - 116.1 1 2 0 0.0089 20 0 0 0 2.73E+06 1.06E+06 - - - 5.6663 0.9999 221125_WJC_METTL3_EV_vs_WT_F09.11848.11848.3 2.37E-07 13/60 K.AKSDQLLSSNENFTNK.V "sp|Q15643|TRIPB_HUMAN,tr|H0YJ97|H0YJ97_HUMAN" 2 1794.8748 2.03 131222 11848 3 1794.874649 599.2989 Thyroid receptor-interacting protein 11 OS=Homo sapiens OX=9606 GN=TRIP11 PE=1 SV=3 6.11 2362.1 - 1.18E+06 - - - -0.088 - 2.725 0.483 - 202.1 1 2 1 -0.0002 16 0 0 0 2.28E+07 1.12E+07 - - - 6.4971 1 221125_WJC_METTL3_EV_vs_WT_F09.11850.11850.3 4.60E-08 Dec-72 K.YNDDSDDSYFTSSSR[166.11]PTAR[166.11].R tr|H0Y6A0|H0Y6A0_HUMAN 1 2202.9205 1.17 131224 11850 3 2202.92417 735.3141 ADP-ribosylation factor GTPase-activating protein 3 (Fragment) OS=Homo sapiens OX=9606 GN=ARFGAP3 PE=1 SV=1 4.14 2362.4 - 247517 - - - 1.6778 - 2.728 0.687 - 187.3 1 2 0 0.0037 19 0 0 0 3.57E+06 3.06E+06 - - - 8.6639 1 221125_WJC_METTL3_EV_vs_WT_F09.11855.11855.3 4.17E-08 18/64 R.TDEEGK[136.11]DVPDHAVLEMK[136.11].A "sp|Q9BUJ2|HNRL1_HUMAN,tr|A0A0A0MRA5|A0A0A0MRA5_HUMAN,tr|M0R3F1|M0R3F1_HUMAN,tr|B7Z4B8|B7Z4B8_HUMAN" 4 1927.9168 2.09 131229 11855 3 1927.916406 643.6462 Heterogeneous nuclear ribonucleoprotein U-like protein 1 OS=Homo sapiens OX=9606 GN=HNRNPUL1 PE=1 SV=2 4.29 2363 - 158102 - - - -0.2085 - 3.811 0.658 - 447.9 1 2 1 -0.0004 17 0 0 0 4.38E+06 2.10E+06 - - - 9.2559 0.9121 221125_WJC_METTL3_EV_vs_WT_F09.11858.11858.4 0.0206 Dec-78 R.K[136.11]IELFGR[166.11]PHNVQPN.W sp|Q86U44|MTA70_HUMAN 1 1665.907 0.02 131231 11858 4 1665.91038 417.484 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 8.75 2363.4 - 6.05E+06 - - - 2.0325 - 2.31 0.325 - 158.7 1 1 0 0.0034 14 0 0 0 2.48E+07 1.61E+09 - - - 2.3586 0.9896 221125_WJC_METTL3_EV_vs_WT_F09.11863.11863.2 0.13 26-Oct R.K[136.11]IELFGR[166.11]PHNVQPN.W sp|Q86U44|MTA70_HUMAN 1 1665.907 0.001 131236 11863 2 1665.907951 833.9608 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 8.75 2364 - 185033 - - - 0.5745 - 2.325 0.443 - 194.3 1 1 0 0.001 14 0 0 0 0.00E+00 9.88E+07 - - - 4.43 0.9963 221125_WJC_METTL3_EV_vs_WT_F09.11866.11866.3 0.00319 Aug-76 R.SPLLAGGSPPQPVVPAHK[136.11]DK[136.11].S "sp|Q8NFH5|NUP35_HUMAN,tr|F8WCF5|F8WCF5_HUMAN,tr|F8WEL4|F8WEL4_HUMAN,tr|C9JIY9|C9JIY9_HUMAN,tr|C9IYQ7|C9IYQ7_HUMAN" 5 2010.1233 2.63 131239 11866 3 2010.128195 671.0484 Nucleoporin NUP35 OS=Homo sapiens OX=9606 GN=NUP35 PE=1 SV=1 8.33 2364.4 - 109263 - - - 2.4297 - 1.765 0.383 - 54.4 1 2 1 0.0049 20 0 0 0 2.87E+06 1.09E+06 - - - 4.1871 0.9998 221125_WJC_METTL3_EV_vs_WT_F09.11873.11873.3 1.61E-05 Nov-72 K.YNDDSDDSYFTSSSRPTAR.R tr|H0Y6A0|H0Y6A0_HUMAN 1 2182.9039 1.17 131243 11873 3 2182.893184 728.6419 ADP-ribosylation factor GTPase-activating protein 3 (Fragment) OS=Homo sapiens OX=9606 GN=ARFGAP3 PE=1 SV=1 4.14 2365.3 - 284845 - - - -4.9246 - 2.426 0.679 - 156.1 1 2 0 -0.0107 19 0 0 0 3.57E+06 3.06E+06 - - - 8.2845 0.9998 221125_WJC_METTL3_EV_vs_WT_F09.11875.11875.4 4.15E-05 13/96 R.QLSILVHPDK[136.11]NQDDADR[166.11].A sp|O75937|DNJC8_HUMAN 1 1980.9984 0.67 131245 11875 4 1980.995327 496.2569 DnaJ homolog subfamily C member 8 OS=Homo sapiens OX=9606 GN=DNAJC8 PE=1 SV=2 4.56 2365.5 - 234923 - - - -1.5452 - 2.208 0.467 - 110.2 1 2 1 -0.0031 17 0 0 0 1.42E+07 2.12E+07 - - - 3.5649 1 221125_WJC_METTL3_EV_vs_WT_F09.11876.11876.3 1.79E-16 16/100 R.NEGQLNGETNTPIEGNQAGDAAASAR.S "sp|P18583|SON_HUMAN,tr|J3QSZ5|J3QSZ5_HUMAN" 2 2584.175 1.94 131246 11876 3 2584.17716 862.3989 Protein SON OS=Homo sapiens OX=9606 GN=SON PE=1 SV=4 4 2365.6 - 178996 - - - 0.8498 - 3.597 0.758 - 255.3 1 2 0 0.0022 26 0 0 0 4.20E+07 2.17E+07 - - - 9.9354 0.9978 221125_WJC_METTL3_EV_vs_WT_F09.11878.11878.3 0.00119 Sep-64 R.QLSILVHPDK[136.11]NQDDADR[166.11].A sp|O75937|DNJC8_HUMAN 1 1980.9984 0.9 131248 11878 3 1980.997838 661.3401 DnaJ homolog subfamily C member 8 OS=Homo sapiens OX=9606 GN=DNAJC8 PE=1 SV=2 4.56 2365.9 - 100327 - - - -0.2776 - 1.824 0.342 - 95.5 1 2 1 -0.0006 17 0 0 0 8.52E+06 9.50E+06 - - - 3.8712 0.9985 221125_WJC_METTL3_EV_vs_WT_F09.11894.11894.2 0.245 22-Oct R.K[136.11]LEEDLLVEVSR.Y sp|Q9Y259|CHKB_HUMAN 1 1436.7966 - 131259 11894 2 1436.798449 719.4056 Choline\ethanolamine kinase OS=Homo sapiens OX=9606 GN=CHKB PE=1 SV=3 4.41 2367.9 - 1.11E+06 - - - 1.2799 - 1.697 0.268 - 213.6 1 2 0 0.0018 12 0 0 0 - - - - - 2.4114 1 221125_WJC_METTL3_EV_vs_WT_F09.11924.11924.3 9.03E-07 Sep-68 K.K[136.11]EDEDPQDGGSLASTLSK[136.11].L sp|Q9UKJ3|GPTC8_HUMAN 1 1891.8982 1.7 131276 11924 3 1891.897548 631.64 G patch domain-containing protein 8 OS=Homo sapiens OX=9606 GN=GPATCH8 PE=1 SV=2 4.11 2371.7 - 204040 - - - -0.3346 - 2.229 0.575 - 79.6 1 2 0 -0.0006 18 0 0 0 8.09E+06 4.75E+06 - - - 6.9465 0.9999 221125_WJC_METTL3_EV_vs_WT_F09.11933.11933.3 9.60E-05 Oct-44 R.K[136.11]IHIDLPNEQAR[166.11].L "sp|P62333|PRS10_HUMAN,tr|A0A087X2I1|A0A087X2I1_HUMAN" 2 1450.8011 1.87 131281 11933 3 1450.799613 484.6077 26S proteasome regulatory subunit 10B OS=Homo sapiens OX=9606 GN=PSMC6 PE=1 SV=1 6.75 2372.9 - 419199 - - - -1.047 - 2.349 0.426 - 222.1 1 2 0 -0.0015 12 0 0 0 1.95E+07 1.04E+07 - - - 5.6562 0.9999 221125_WJC_METTL3_EV_vs_WT_F09.11941.11941.4 4.74E-07 14/96 R.QLSILVHPDKNQDDADR.A sp|O75937|DNJC8_HUMAN 1 1962.9759 0.67 131287 11941 4 1962.980171 491.7513 DnaJ homolog subfamily C member 8 OS=Homo sapiens OX=9606 GN=DNAJC8 PE=1 SV=2 4.56 2373.9 - 337723 - - - 2.1666 - 2.777 0.588 - 159.3 1 2 1 0.0043 17 0 0 0 1.42E+07 2.12E+07 - - - 4.6974 1 221125_WJC_METTL3_EV_vs_WT_F09.11944.11944.3 1.03E-06 Oct-68 K.KEDEDPQDGGSLASTLSK.L sp|Q9UKJ3|GPTC8_HUMAN 1 1875.8698 1.7 131290 11944 3 1875.867891 626.2972 G patch domain-containing protein 8 OS=Homo sapiens OX=9606 GN=GPATCH8 PE=1 SV=2 4.11 2374.3 - 243259 - - - -1.0075 - 1.969 0.53 - 94.6 1 2 0 -0.0019 18 0 0 0 8.09E+06 4.75E+06 - - - 6.1356 0.9999 221125_WJC_METTL3_EV_vs_WT_F09.11945.11945.3 1.92E-06 Oct-76 K.ASESSK[136.11]PWPDATYGTGSASR[166.11].A "sp|Q9Y2W1|TR150_HUMAN,tr|A0A3B3ITZ9|A0A3B3ITZ9_HUMAN" 2 2071.9566 3.68 131291 11945 3 2071.956799 691.6595 Thyroid hormone receptor-associated protein 3 OS=Homo sapiens OX=9606 GN=THRAP3 PE=1 SV=2 6.11 2374.4 - 239091 - - - 0.1047 - 2.288 0.431 - 83.5 1 2 0 0.0002 20 0 0 0 3.44E+07 9.35E+06 - - - 5.3531 1 221125_WJC_METTL3_EV_vs_WT_F09.11950.11950.3 1.31E-08 16/68 R.RKPEDVLDDDDAGSAPLK.S "sp|P35613|BASI_HUMAN,tr|A0A087WUV8|A0A087WUV8_HUMAN,tr|A0A7P0TA85|A0A7P0TA85_HUMAN" 3 1939.9487 1.27 131294 11950 3 1939.947242 647.6568 Basigin OS=Homo sapiens OX=9606 GN=BSG PE=1 SV=2 4.17 2375.1 - 204098 - - - -0.7516 - 2.938 0.58 - 288 1 2 0 -0.0015 18 0 0 0 8.34E+06 6.55E+06 - - - 7.6897 1 221125_WJC_METTL3_EV_vs_WT_F09.11961.11961.3 2.32E-11 17/100 R.NEGQLNGETNTPIEGNQAGDAAASAR[166.11].S "sp|P18583|SON_HUMAN,tr|J3QSZ5|J3QSZ5_HUMAN" 2 2594.1832 1.94 131300 11961 3 2594.181193 865.735 Protein SON OS=Homo sapiens OX=9606 GN=SON PE=1 SV=4 4 2376.7 - 225894 - - - -0.7868 - 3.381 0.671 - 266.1 1 2 0 -0.002 26 0 0 0 4.20E+07 2.17E+07 - - - 8.823 1 221125_WJC_METTL3_EV_vs_WT_F09.11965.11965.4 6.72E-15 27/120 K.MGVSPGNPVDSHAYPHIQNSK.Q "sp|Q6W2J9|BCOR_HUMAN,tr|H7BZ37|H7BZ37_HUMAN,tr|H7C2V9|H7C2V9_HUMAN,tr|H7BYY2|H7BYY2_HUMAN,tr|H7C231|H7C231_HUMAN" 5 2234.0538 2.06 131302 11965 4 2234.056516 559.5207 BCL-6 corepressor OS=Homo sapiens OX=9606 GN=BCOR PE=1 SV=1 6.69 2377.2 - 705371 - - - 1.1933 - 5.43 0.666 - 654.6 1 2 0 0.0027 21 0 0 0 1.93E+07 9.37E+06 - - - 5.5815 0.9999 221125_WJC_METTL3_EV_vs_WT_F09.11967.11967.3 0.000853 Sep-44 R.KIHIDLPNEQAR.L "sp|P62333|PRS10_HUMAN,tr|A0A087X2I1|A0A087X2I1_HUMAN" 2 1432.7787 1.87 131304 11967 3 1432.780412 478.6002 26S proteasome regulatory subunit 10B OS=Homo sapiens OX=9606 GN=PSMC6 PE=1 SV=1 6.75 2377.5 - 239887 - - - 1.2214 - 2.219 0.413 - 133.1 1 2 0 0.0018 12 0 0 0 1.95E+07 1.04E+07 - - - 5.3534 0.7936 221125_WJC_METTL3_EV_vs_WT_F09.11976.11976.3 0.0934 Jun-76 K.TQEEGEERAESEQEAYLRED.- "sp|Q9NR28|DBLOH_HUMAN,tr|A0A024RBT2|A0A024RBT2_HUMAN" 2 2397.0204 1.85 131311 11976 3 2397.026865 800.0141 "Diablo homolog, mitochondrial OS=Homo sapiens OX=9606 GN=DIABLO PE=1 SV=1" 4.05 2378.7 - 82641.6 - - - 2.6883 - 1.05 0.251 - 29.4 1 2 2 0.0064 20 0 0 0 6.98E+05 3.78E+05 - - - 1.455 1 221125_WJC_METTL3_EV_vs_WT_F09.11979.11979.3 1.22E-08 Oct-80 K.MGVSPGNPVDSHAYPHIQNSK.Q "sp|Q6W2J9|BCOR_HUMAN,tr|H7BZ37|H7BZ37_HUMAN,tr|H7C2V9|H7C2V9_HUMAN,tr|H7BYY2|H7BYY2_HUMAN,tr|H7C231|H7C231_HUMAN" 5 2234.0538 2.68 131312 11979 3 2234.058955 745.6919 BCL-6 corepressor OS=Homo sapiens OX=9606 GN=BCOR PE=1 SV=1 6.69 2379.2 - 100682 - - - 2.2851 - 2.445 0.64 - 107.1 1 2 0 0.0051 21 0 0 0 3.36E+06 1.25E+06 - - - 7.8174 0.9955 221125_WJC_METTL3_EV_vs_WT_F09.11981.11981.3 0.00736 Jul-68 R.R[166.11]K[136.11]PEDVLDDDDAGSAPLK[136.11].S "sp|P35613|BASI_HUMAN,tr|A0A087WUV8|A0A087WUV8_HUMAN,tr|A0A7P0TA85|A0A7P0TA85_HUMAN" 3 1965.9854 1.26 131314 11981 3 1965.993845 656.3357 Basigin OS=Homo sapiens OX=9606 GN=BSG PE=1 SV=2 4.17 2379.4 - 99783.8 - - - 4.3108 - 1.821 0.348 - 59.1 1 2 0 0.0085 18 0 0 0 8.28E+06 6.55E+06 - - - 3.91 0.9875 221125_WJC_METTL3_EV_vs_WT_F09.11984.11984.3 0.196 Apr-76 K.TQEEGEER[166.11]AESEQEAYLR[166.11]ED.- "sp|Q9NR28|DBLOH_HUMAN,tr|A0A024RBT2|A0A024RBT2_HUMAN" 2 2417.037 1.85 131317 11984 3 2417.041385 806.6863 "Diablo homolog, mitochondrial OS=Homo sapiens OX=9606 GN=DIABLO PE=1 SV=1" 4.05 2379.8 - 60472.8 - - - 1.8303 - 1.118 0.375 - 16 1 2 2 0.0044 20 0 0 0 6.98E+05 3.78E+05 - - - 2.9903 1 221125_WJC_METTL3_EV_vs_WT_F09.11988.11988.4 1.56E-08 19/90 K.IFVGGIKEDTEEHHLR.D "sp|Q32P51|RA1L2_HUMAN,sp|P09651|ROA1_HUMAN,sp|P22626|ROA2_HUMAN,tr|A0A7I2YQN4|A0A7I2YQN4_HUMAN,tr|A0A7I2YQX9|A0A7I2YQX9_HUMAN,tr|A0A7I2V4N0|A0A7I2V4N0_HUMAN,tr|A0A024RA28|A0A024RA28_HUMAN,tr|A0A7I2V4N1|A0A7I2V4N1_HUMAN,tr|A0A7I2V4I6|A0A7I2V4I6_HUMAN,tr|F8VZ49|F8VZ49_HUMAN,tr|A0A7I2V3R8|A0A7I2V3R8_HUMAN,tr|A0A087WUI2|A0A087WUI2_HUMAN,tr|A0A7I2V4S4|A0A7I2V4S4_HUMAN,tr|F8VTQ5|F8VTQ5_HUMAN,tr|F8W6I7|F8W6I7_HUMAN,tr|A0A7I2V2L6|A0A7I2V2L6_HUMAN,tr|A0A7I2V323|A0A7I2V323_HUMAN,tr|A0A7I2V3W0|A0A7I2V3W0_HUMAN,tr|A0A7I2V5U9|A0A7I2V5U9_HUMAN,tr|A0A2R8Y4L2|A0A2R8Y4L2_HUMAN,tr|A0A7I2V3P1|A0A7I2V3P1_HUMAN,tr|A0A7I2V3P7|A0A7I2V3P7_HUMAN" 22 1878.9588 1.47 131320 11988 4 1878.965587 470.747 Heterogeneous nuclear ribonucleoprotein A1-like 2 OS=Homo sapiens OX=9606 GN=HNRNPA1L2 PE=2 SV=2 5.36 2380.3 - 360141 - - - 3.6063 - 3.523 0.638 - 377.1 1 2 1 0.0068 16 0 0 0 1.12E+07 7.66E+06 - - - 5.2209 1 221125_WJC_METTL3_EV_vs_WT_F09.11990.11990.3 1.87E-14 27/88 R.QPPPAPPEQADGNAPGPQPPPVR.L sp|Q12948|FOXC1_HUMAN 1 2313.1502 3.99 131321 11990 3 2313.15666 772.0573 Forkhead box protein C1 OS=Homo sapiens OX=9606 GN=FOXC1 PE=1 SV=3 4.37 2380.6 - 716184 - - - 2.7953 - 3.878 0.681 - 476.4 1 2 0 0.0065 23 0 0 0 1.07E+08 2.68E+07 - - - 9.3102 0.9876 221125_WJC_METTL3_EV_vs_WT_F09.11991.11991.4 0.0127 Jul-78 K.VIEPLK[136.11]DFHK[136.11]DEVR[166.11].L sp|P49915|GUAA_HUMAN 1 1749.9624 0.92 131322 11991 4 1749.966596 438.4979 GMP synthase [glutamine-hydrolyzing] OS=Homo sapiens OX=9606 GN=GMPS PE=1 SV=1 5.48 2380.7 - 132906 - - - 2.4035 - 1.718 0.282 - 47.4 1 2 2 0.0042 14 0 0 0 3.08E+06 3.35E+06 - - - 1.8763 0.9998 221125_WJC_METTL3_EV_vs_WT_F09.11995.11995.3 0.0167 Dec-56 R.R[166.11]NLDIER[166.11]PTYTNLNR[166.11].L "sp|Q9NY65|TBA8_HUMAN,sp|Q6PEY2|TBA3E_HUMAN,sp|P0DPH7|TBA3C_HUMAN,sp|Q71U36|TBA1A_HUMAN,sp|P0DPH8|TBA3D_HUMAN,sp|P68366|TBA4A_HUMAN,sp|P68363|TBA1B_HUMAN,sp|Q9BQE3|TBA1C_HUMAN,tr|F8VVB9|F8VVB9_HUMAN,tr|C9JDS9|C9JDS9_HUMAN,tr|A0A7P0TA31|A0A7P0TA31_HUMAN,tr|F5H5D3|F5H5D3_HUMAN,tr|C9J2C0|C9J2C0_HUMAN,tr|F8VQQ4|F8VQQ4_HUMAN,tr|A0A7P0T945|A0A7P0T945_HUMAN" 15 1904.0007 0.59 131326 11995 3 1904.006011 635.6742 Tubulin alpha-8 chain OS=Homo sapiens OX=9606 GN=TUBA8 PE=1 SV=1 8.74 2381.2 - 105467 - - - 2.8062 - 2.385 0.429 - 84.9 1 2 0 0.0053 15 0 0 0 8.30E+06 1.41E+07 - - - 5.5895 1 221125_WJC_METTL3_EV_vs_WT_F09.12004.12004.3 8.81E-06 Dec-68 K.NQDEC[160.03]IVALHDC[160.03]NGDVNK[136.11].A "sp|Q5T6F2|UBAP2_HUMAN,tr|A0A804HLJ4|A0A804HLJ4_HUMAN,tr|A0A0D9SFI5|A0A0D9SFI5_HUMAN,tr|A0A804HIK1|A0A804HIK1_HUMAN" 4 2107.9143 4.23 131333 12004 3 2107.913106 703.6454 Ubiquitin-associated protein 2 OS=Homo sapiens OX=9606 GN=UBAP2 PE=1 SV=1 4.22 2382.4 - 118570 - - - -0.5437 - 2.495 0.499 - 152 1 2 0 -0.0011 18 0 0 0 8.06E+06 1.91E+06 - - - 6.3797 0.9984 221125_WJC_METTL3_EV_vs_WT_F09.12007.12007.3 0.0261 Jun-64 R.DHANYEEDENGDITPIK.A "sp|Q99547|MPH6_HUMAN,tr|H3BNT4|H3BNT4_HUMAN,tr|H3BSB3|H3BSB3_HUMAN" 3 1958.8494 1.29 131336 12007 3 1958.857097 653.9571 M-phase phosphoprotein 6 OS=Homo sapiens OX=9606 GN=MPHOSPH6 PE=1 SV=2 4.01 2382.8 - 57282.6 - - - 3.9396 - 1.202 0.495 - 35.1 1 2 0 0.0077 17 0 0 0 1.63E+06 1.27E+06 - - - 4.5214 0.9999 221125_WJC_METTL3_EV_vs_WT_F09.12010.12010.4 3.64E-05 10/114 K.VVTTNYK[136.11]PVANHQYNIEYER[166.11].K sp|P13984|T2FB_HUMAN 1 2455.2251 1.27 131337 12010 4 2455.230663 614.8135 General transcription factor IIF subunit 2 OS=Homo sapiens OX=9606 GN=GTF2F2 PE=1 SV=2 6.72 2383.3 - 353514 - - - 2.2686 - 2.016 0.478 - 47.5 1 2 0 0.0056 20 0 0 0 2.44E+07 1.92E+07 - - - 3.6194 0.9995 221125_WJC_METTL3_EV_vs_WT_F09.12011.12011.4 0.124 15/114 K.VVTTNYKPVANHQYNIEYER.K sp|P13984|T2FB_HUMAN 1 2437.2026 1.27 131338 12011 4 2437.210991 610.3079 General transcription factor IIF subunit 2 OS=Homo sapiens OX=9606 GN=GTF2F2 PE=1 SV=2 6.72 2383.4 - 358292 - - - 3.4334 - 2.603 0.413 - 135.1 1 2 0 0.0084 20 0 0 0 2.44E+07 1.91E+07 - - - 3.1383 1 221125_WJC_METTL3_EV_vs_WT_F09.12012.12012.3 1.14E-06 Nov-52 R.DDSFFGETSHNYHK[136.11].F "sp|P43243|MATR3_HUMAN,tr|A8MXP9|A8MXP9_HUMAN,tr|D6R991|D6R991_HUMAN,tr|A0A0R4J2E8|A0A0R4J2E8_HUMAN,tr|H0Y8T4|H0Y8T4_HUMAN,tr|D6REM6|D6REM6_HUMAN" 6 1690.7103 1.39 131339 12012 3 1690.715337 564.5774 Matrin-3 OS=Homo sapiens OX=9606 GN=MATR3 PE=1 SV=2 5.21 2383.5 - 191741 - - - 2.9709 - 2.203 0.639 - 114.4 1 2 0 0.005 14 0 0 0 2.32E+08 1.67E+08 - - - 7.7618 0.9999 221125_WJC_METTL3_EV_vs_WT_F09.12013.12013.4 1.16E-05 Nov-78 R.DDSFFGETSHNYHK[136.11].F "sp|P43243|MATR3_HUMAN,tr|A8MXP9|A8MXP9_HUMAN,tr|D6R991|D6R991_HUMAN,tr|A0A0R4J2E8|A0A0R4J2E8_HUMAN,tr|H0Y8T4|H0Y8T4_HUMAN,tr|D6REM6|D6REM6_HUMAN" 6 1690.7103 1.41 131340 12013 4 1690.715954 423.6849 Matrin-3 OS=Homo sapiens OX=9606 GN=MATR3 PE=1 SV=2 5.21 2383.6 - 171901 - - - 3.3359 - 2.17 0.587 - 50 1 2 0 0.0056 14 0 0 0 1.95E+08 1.38E+08 - - - 4.6156 0.9996 221125_WJC_METTL3_EV_vs_WT_F09.12015.12015.3 0.0108 Aug-76 K.VVTTNYKPVANHQYNIEYER.K sp|P13984|T2FB_HUMAN 1 2437.2026 1.76 131342 12015 3 2437.207347 813.4082 General transcription factor IIF subunit 2 OS=Homo sapiens OX=9606 GN=GTF2F2 PE=1 SV=2 6.72 2383.9 - 72548.7 - - - 1.9383 - 1.708 0.419 - 58.6 1 2 0 0.0047 20 0 0 0 4.97E+06 2.83E+06 - - - 4.5088 1 221125_WJC_METTL3_EV_vs_WT_F09.12016.12016.3 9.19E-11 Sep-64 R.DHANYEEDENGDITPIK[136.11].A "sp|Q99547|MPH6_HUMAN,tr|H3BNT4|H3BNT4_HUMAN,tr|H3BSB3|H3BSB3_HUMAN" 3 1966.8636 1.29 131343 12016 3 1966.870053 656.6285 M-phase phosphoprotein 6 OS=Homo sapiens OX=9606 GN=MPHOSPH6 PE=1 SV=2 4.01 2384 - 64529.8 - - - 3.291 - 2.279 0.687 - 93.1 1 2 0 0.0065 17 0 0 0 1.63E+06 1.27E+06 - - - 8.2786 0.9994 221125_WJC_METTL3_EV_vs_WT_F09.12017.12017.3 0.00304 Jul-76 K.VVTTNYK[136.11]PVANHQYNIEYER[166.11].K sp|P13984|T2FB_HUMAN 1 2455.2251 1.76 131344 12017 3 2455.232149 819.4156 General transcription factor IIF subunit 2 OS=Homo sapiens OX=9606 GN=GTF2F2 PE=1 SV=2 6.72 2384.2 - 64517.5 - - - 2.8739 - 1.705 0.433 - 39.1 1 2 0 0.0071 20 0 0 0 4.97E+06 2.83E+06 - - - 4.66 0.9999 221125_WJC_METTL3_EV_vs_WT_F09.12020.12020.4 3.69E-06 19/84 R.R[166.11]NLDIER[166.11]PTYTNLNR[166.11].L "sp|Q9NY65|TBA8_HUMAN,sp|Q6PEY2|TBA3E_HUMAN,sp|P0DPH7|TBA3C_HUMAN,sp|Q71U36|TBA1A_HUMAN,sp|P0DPH8|TBA3D_HUMAN,sp|P68366|TBA4A_HUMAN,sp|P68363|TBA1B_HUMAN,sp|Q9BQE3|TBA1C_HUMAN,tr|F8VVB9|F8VVB9_HUMAN,tr|C9JDS9|C9JDS9_HUMAN,tr|A0A7P0TA31|A0A7P0TA31_HUMAN,tr|F5H5D3|F5H5D3_HUMAN,tr|C9J2C0|C9J2C0_HUMAN,tr|F8VQQ4|F8VQQ4_HUMAN,tr|A0A7P0T945|A0A7P0T945_HUMAN" 15 1904.0007 0.61 131345 12020 4 1904.006798 477.0074 Tubulin alpha-8 chain OS=Homo sapiens OX=9606 GN=TUBA8 PE=1 SV=1 8.74 2384.6 - 528406 - - - 3.2195 - 2.7 0.486 - 452.1 1 2 0 0.0061 15 0 0 0 8.42E+06 1.37E+07 - - - 3.8098 0.9999 221125_WJC_METTL3_EV_vs_WT_F09.12021.12021.3 1.48E-07 19/56 R.RNLDIERPTYTNLNR.L "sp|Q9NY65|TBA8_HUMAN,sp|Q6PEY2|TBA3E_HUMAN,sp|P0DPH7|TBA3C_HUMAN,sp|Q71U36|TBA1A_HUMAN,sp|P0DPH8|TBA3D_HUMAN,sp|P68366|TBA4A_HUMAN,sp|P68363|TBA1B_HUMAN,sp|Q9BQE3|TBA1C_HUMAN,tr|F8VVB9|F8VVB9_HUMAN,tr|C9JDS9|C9JDS9_HUMAN,tr|A0A7P0TA31|A0A7P0TA31_HUMAN,tr|F5H5D3|F5H5D3_HUMAN,tr|C9J2C0|C9J2C0_HUMAN,tr|F8VQQ4|F8VQQ4_HUMAN,tr|A0A7P0T945|A0A7P0T945_HUMAN" 15 1873.9759 0.59 131346 12021 3 1873.981285 625.6659 Tubulin alpha-8 chain OS=Homo sapiens OX=9606 GN=TUBA8 PE=1 SV=1 8.74 2384.8 - 319216 - - - 2.896 - 2.754 0.544 - 216.7 1 2 0 0.0054 15 0 0 0 8.30E+06 1.41E+07 - - - 7.247 0.9999 221125_WJC_METTL3_EV_vs_WT_F09.12022.12022.3 4.03E-05 17/52 R.DDSFFGETSHNYHK.F "sp|P43243|MATR3_HUMAN,tr|A8MXP9|A8MXP9_HUMAN,tr|D6R991|D6R991_HUMAN,tr|A0A0R4J2E8|A0A0R4J2E8_HUMAN,tr|H0Y8T4|H0Y8T4_HUMAN,tr|D6REM6|D6REM6_HUMAN" 6 1682.6961 1.39 131347 12022 3 1682.703022 561.906 Matrin-3 OS=Homo sapiens OX=9606 GN=MATR3 PE=1 SV=2 5.21 2384.9 - 561214 - - - 4.1053 - 3.05 0.622 - 346.3 1 2 0 0.0069 14 0 0 0 2.33E+08 1.67E+08 - - - 8.4363 0.9998 221125_WJC_METTL3_EV_vs_WT_F09.12024.12024.4 6.56E-06 15/78 K.VIEPLKDFHKDEVR.L sp|P49915|GUAA_HUMAN 1 1723.9257 0.92 131349 12024 4 1723.929665 431.9887 GMP synthase [glutamine-hydrolyzing] OS=Homo sapiens OX=9606 GN=GMPS PE=1 SV=1 5.48 2385.1 - 168344 - - - 2.2884 - 2.746 0.541 - 258.5 1 2 2 0.0039 14 0 0 0 3.08E+06 3.35E+06 - - - 4.3014 0.9998 221125_WJC_METTL3_EV_vs_WT_F09.12030.12030.4 1.54E-06 19/84 R.RNLDIERPTYTNLNR.L "sp|Q9NY65|TBA8_HUMAN,sp|Q6PEY2|TBA3E_HUMAN,sp|P0DPH7|TBA3C_HUMAN,sp|Q71U36|TBA1A_HUMAN,sp|P0DPH8|TBA3D_HUMAN,sp|P68366|TBA4A_HUMAN,sp|P68363|TBA1B_HUMAN,sp|Q9BQE3|TBA1C_HUMAN,tr|F8VVB9|F8VVB9_HUMAN,tr|C9JDS9|C9JDS9_HUMAN,tr|A0A7P0TA31|A0A7P0TA31_HUMAN,tr|F5H5D3|F5H5D3_HUMAN,tr|C9J2C0|C9J2C0_HUMAN,tr|F8VQQ4|F8VQQ4_HUMAN,tr|A0A7P0T945|A0A7P0T945_HUMAN" 15 1873.9759 0.59 131353 12030 4 1873.982743 469.5012 Tubulin alpha-8 chain OS=Homo sapiens OX=9606 GN=TUBA8 PE=1 SV=1 8.74 2386 - 490390 - - - 3.674 - 3.254 0.477 - 465.5 1 2 0 0.0069 15 0 0 0 8.17E+06 1.38E+07 - - - 3.7981 0.9997 221125_WJC_METTL3_EV_vs_WT_F09.12032.12032.2 0.00527 18-Aug K.FADLSEAANR.N "sp|P08670|VIME_HUMAN,tr|B0YJC5|B0YJC5_HUMAN,tr|B0YJC4|B0YJC4_HUMAN" 3 1092.52 2.48 131355 12032 2 1092.519564 547.2673 Vimentin OS=Homo sapiens OX=9606 GN=VIM PE=1 SV=4 4.37 2386.2 - 130540 - - - -0.3872 - 1.808 0.413 - 196.9 1 2 0 -0.0004 10 0 0 0 3.32E+06 1.34E+06 - - - 3.7444 0.9999 221125_WJC_METTL3_EV_vs_WT_F09.12036.12036.3 4.92E-05 13/40 R.SLGTADVHFER[166.11].K "sp|Q86V81|THOC4_HUMAN,tr|E9PB61|E9PB61_HUMAN" 2 1240.6076 0.76 131357 12036 3 1240.610946 414.5431 THO complex subunit 4 OS=Homo sapiens OX=9606 GN=ALYREF PE=1 SV=3 5.3 2386.8 - 309239 - - - 2.7212 - 2.556 0.506 - 214.3 1 2 0 0.0034 11 0 0 0 6.88E+06 9.04E+06 - - - 6.8464 0.9999 221125_WJC_METTL3_EV_vs_WT_F09.12046.12046.3 8.99E-05 14/40 R.SLGTADVHFER.K "sp|Q86V81|THOC4_HUMAN,tr|E9PB61|E9PB61_HUMAN" 2 1230.5993 0.75 131365 12046 3 1230.602609 411.207 THO complex subunit 4 OS=Homo sapiens OX=9606 GN=ALYREF PE=1 SV=3 5.3 2388.1 - 283818 - - - 2.6889 - 2.615 0.509 - 249.7 1 2 0 0.0033 11 0 0 0 6.81E+06 9.03E+06 - - - 6.9447 1 221125_WJC_METTL3_EV_vs_WT_F09.12053.12053.2 2.95E-06 16-Dec F.GETSHNYHK.F "sp|P43243|MATR3_HUMAN,tr|A8MXP9|A8MXP9_HUMAN,tr|D6R991|D6R991_HUMAN,tr|A0A0R4J2E8|A0A0R4J2E8_HUMAN,tr|H0Y8T4|H0Y8T4_HUMAN,tr|D6REM6|D6REM6_HUMAN" 6 1071.4734 1.21 131370 12053 2 1071.475282 536.744 Matrin-3 OS=Homo sapiens OX=9606 GN=MATR3 PE=1 SV=2 6.92 2389 - 455456 - - - 1.7835 - 2.216 0.611 - 551.6 1 1 0 0.0019 9 0 0 0 1.49E+07 1.23E+07 - - - 5.8553 1 221125_WJC_METTL3_EV_vs_WT_F09.12061.12061.4 9.72E-08 16/78 R.DDSFFGETSHNYHK.F "sp|P43243|MATR3_HUMAN,tr|A8MXP9|A8MXP9_HUMAN,tr|D6R991|D6R991_HUMAN,tr|A0A0R4J2E8|A0A0R4J2E8_HUMAN,tr|H0Y8T4|H0Y8T4_HUMAN,tr|D6REM6|D6REM6_HUMAN" 6 1682.6961 1.41 131376 12061 4 1682.699657 421.6813 Matrin-3 OS=Homo sapiens OX=9606 GN=MATR3 PE=1 SV=2 5.21 2390.1 - 9.28E+06 - - - 2.1055 - 2.486 0.6 - 121.4 1 2 0 0.0035 14 0 0 0 1.95E+08 1.38E+08 - - - 4.7789 0.9999 221125_WJC_METTL3_EV_vs_WT_F09.12063.12063.2 7.43E-06 26-Aug R.DDSFFGETSHNYHK[136.11].F "sp|P43243|MATR3_HUMAN,tr|A8MXP9|A8MXP9_HUMAN,tr|D6R991|D6R991_HUMAN,tr|A0A0R4J2E8|A0A0R4J2E8_HUMAN,tr|H0Y8T4|H0Y8T4_HUMAN,tr|D6REM6|D6REM6_HUMAN" 6 1690.7103 1.31 131378 12063 2 1690.70987 846.3624 Matrin-3 OS=Homo sapiens OX=9606 GN=MATR3 PE=1 SV=2 5.21 2390.4 - 131648 - - - -0.2626 - 1.627 0.63 - 187 1 2 0 -0.0004 14 0 0 0 4.62E+06 3.53E+06 - - - 4.9155 0.9999 221125_WJC_METTL3_EV_vs_WT_F09.12064.12064.4 5.21E-05 11/108 R.YGDSEFTVQSTTGHC[160.03]VHMR.G sp|P52597|HNRPF_HUMAN 1 2210.9473 0.71 131379 12064 4 2210.945995 553.7441 Heterogeneous nuclear ribonucleoprotein F OS=Homo sapiens OX=9606 GN=HNRNPF PE=1 SV=3 5.99 2390.5 - 112915 - - - -0.607 - 2.168 0.466 - 96.2 1 2 0 -0.0013 19 0 0 0 2.19E+06 3.10E+06 - - - 3.5435 1 221125_WJC_METTL3_EV_vs_WT_F09.12069.12069.2 1.05E-06 26-Oct R.DDSFFGETSHNYHK.F "sp|P43243|MATR3_HUMAN,tr|A8MXP9|A8MXP9_HUMAN,tr|D6R991|D6R991_HUMAN,tr|A0A0R4J2E8|A0A0R4J2E8_HUMAN,tr|H0Y8T4|H0Y8T4_HUMAN,tr|D6REM6|D6REM6_HUMAN" 6 1682.6961 1.31 131382 12069 2 1682.695086 842.3553 Matrin-3 OS=Homo sapiens OX=9606 GN=MATR3 PE=1 SV=2 5.21 2391.2 - 229398 - - - -0.6109 - 2.178 0.669 - 312.2 1 2 0 -0.001 14 0 0 0 4.62E+06 3.53E+06 - - - 5.9353 0.9856 221125_WJC_METTL3_EV_vs_WT_F09.12070.12070.2 2.87E-05 22-Aug D.SFFGETSHNYHK[136.11].F "sp|P43243|MATR3_HUMAN,tr|A8MXP9|A8MXP9_HUMAN,tr|D6R991|D6R991_HUMAN,tr|A0A0R4J2E8|A0A0R4J2E8_HUMAN,tr|H0Y8T4|H0Y8T4_HUMAN,tr|D6REM6|D6REM6_HUMAN" 6 1460.6564 1.75 131383 12070 2 1460.654052 731.3355 Matrin-3 OS=Homo sapiens OX=9606 GN=MATR3 PE=1 SV=2 6.66 2391.3 - 64309 - - - -1.6267 - 1.576 0.585 - 148.5 1 1 0 -0.0024 12 0 0 0 1.81E+06 1.03E+06 - - - 4.558 0.8482 221125_WJC_METTL3_EV_vs_WT_F09.12089.12089.4 3.22 Jun-78 R.LVLTQEQLHQLHSR.L "sp|Q14203|DCTN1_HUMAN,tr|A0A804CDA6|A0A804CDA6_HUMAN,tr|E7EX90|E7EX90_HUMAN,tr|A0A7P0Z4C3|A0A7P0Z4C3_HUMAN,tr|E7EWF7|E7EWF7_HUMAN" 5 1700.9322 1.53 131396 12089 4 1700.932679 426.2403 Dynactin subunit 1 OS=Homo sapiens OX=9606 GN=DCTN1 PE=1 SV=3 6.92 2393.8 - 95623.5 - - - 0.2804 - 1.145 0.111 - 20.8 1 2 0 0.0005 14 0 0 0 1.95E+06 1.28E+06 - - - 0.2413 0.9998 221125_WJC_METTL3_EV_vs_WT_F09.12099.12099.4 0.00362 13/126 K.TKPIVKPQTSPEYGQGINPISR.L sp|O95793|STAU1_HUMAN 1 2409.3016 2.02 131403 12099 4 2409.308586 603.3327 Double-stranded RNA-binding protein Staufen homolog 1 OS=Homo sapiens OX=9606 GN=STAU1 PE=1 SV=2 9.7 2395.1 - 465947 - - - 2.8959 - 2.617 0.441 - 103.4 1 2 0 0.007 22 0 0 0 3.45E+07 1.71E+07 - - - 3.3773 0.9988 221125_WJC_METTL3_EV_vs_WT_F09.12102.12102.3 0.00165 Nov-44 K.TRLEQEIATYRR.L "sp|Q04695|K1C17_HUMAN,sp|P02533|K1C14_HUMAN,sp|P35900|K1C20_HUMAN,sp|P08779|K1C16_HUMAN,tr|A0A3B3IS58|A0A3B3IS58_HUMAN,tr|F5GWP8|F5GWP8_HUMAN" 6 1534.8216 76.66 131406 12102 3 1534.823276 512.6145 "Keratin, type I cytoskeletal 17 OS=Homo sapiens OX=9606 GN=KRT17 PE=1 SV=2" 8.41 2395.5 - 164370 - - - 1.0992 - 1.985 0.36 - 94.7 1 2 1 0.0017 12 0 0 0 3.79E+06 4.95E+04 - - - 4.4536 1 221125_WJC_METTL3_EV_vs_WT_F09.12103.12103.3 5.23E-06 Aug-84 K.TKPIVKPQTSPEYGQGINPISR.L sp|O95793|STAU1_HUMAN 1 2409.3016 2.21 131407 12103 3 2409.302143 804.1078 Double-stranded RNA-binding protein Staufen homolog 1 OS=Homo sapiens OX=9606 GN=STAU1 PE=1 SV=2 9.7 2395.6 - 100908 - - - 0.2216 - 2.034 0.55 - 59 1 2 0 0.0005 22 0 0 0 8.40E+06 3.80E+06 - - - 6.3551 1 221125_WJC_METTL3_EV_vs_WT_F09.12106.12106.3 1.68E-13 20/84 R.SGERPVTAGEEDEQVPDSIDAR.E "sp|Q9Y3D0|CIA2B_HUMAN,tr|H3BNV7|H3BNV7_HUMAN" 2 2356.0779 3.25 131408 12106 3 2356.082971 786.3666 Cytosolic iron-sulfur assembly component 2B OS=Homo sapiens OX=9606 GN=CIAO2B PE=1 SV=1 3.95 2396.1 - 194041 - - - 2.1625 - 3.494 0.615 - 303.2 1 2 0 0.0051 22 0 0 0 3.15E+07 9.67E+06 - - - 8.3613 0.9997 221125_WJC_METTL3_EV_vs_WT_F09.12107.12107.4 0.000266 13/102 R.VLGTEAVQDPTKVEAHVR.A sp|O43395|PRPF3_HUMAN 1 1948.0378 2.63 131409 12107 4 1948.038757 488.0167 U4\U6 small nuclear ribonucleoprotein Prp3 OS=Homo sapiens OX=9606 GN=PRPF3 PE=1 SV=2 5.44 2396.2 - 95266 - - - 0.4964 - 2.169 0.44 - 74.1 1 2 1 0.001 18 0 0 0 2.63E+06 1.00E+06 - - - 3.3207 0.9982 221125_WJC_METTL3_EV_vs_WT_F09.12112.12112.3 0.025 Jun-76 K.ASESSKPWPDATYGTGSASR.A "sp|Q9Y2W1|TR150_HUMAN,tr|A0A3B3ITZ9|A0A3B3ITZ9_HUMAN" 2 2053.9341 3.44 131414 12112 3 2053.930655 685.652 Thyroid hormone receptor-associated protein 3 OS=Homo sapiens OX=9606 GN=THRAP3 PE=1 SV=2 6.11 2396.9 - 101447 - - - -1.6831 - 1.316 0.355 - 33.3 1 2 0 -0.0035 20 0 0 0 4.20E+06 1.22E+06 - - - 3.1631 1 221125_WJC_METTL3_EV_vs_WT_F09.12114.12114.3 5.34E-07 18/84 R.SGER[166.11]PVTAGEEDEQVPDSIDAR[166.11].E "sp|Q9Y3D0|CIA2B_HUMAN,tr|H3BNV7|H3BNV7_HUMAN" 2 2376.0944 3.24 131416 12114 3 2376.095147 793.0387 Cytosolic iron-sulfur assembly component 2B OS=Homo sapiens OX=9606 GN=CIAO2B PE=1 SV=1 3.95 2397.1 - 64874.6 - - - 0.3076 - 3.604 0.619 - 244.4 1 2 0 0.0007 22 0 0 0 3.14E+07 9.67E+06 - - - 8.4806 0.9998 221125_WJC_METTL3_EV_vs_WT_F09.12117.12117.4 0.000621 12/126 K.TK[136.11]PIVK[136.11]PQTSPEYGQGINPISR[166.11].L sp|O95793|STAU1_HUMAN 1 2435.3383 2.01 131417 12117 4 2435.345145 609.8418 Double-stranded RNA-binding protein Staufen homolog 1 OS=Homo sapiens OX=9606 GN=STAU1 PE=1 SV=2 9.7 2397.6 - 496016 - - - 2.8193 - 2.348 0.457 - 80.4 1 2 0 0.0069 22 0 0 0 3.44E+07 1.71E+07 - - - 3.4811 0.9996 221125_WJC_METTL3_EV_vs_WT_F09.12118.12118.4 3.02E-05 13/108 K.ASELGHSLNENVLKPAQEK.V "sp|Q8N6T3|ARFG1_HUMAN,tr|F8VWH9|F8VWH9_HUMAN,tr|E5RHT6|E5RHT6_HUMAN,tr|F8W1U7|F8W1U7_HUMAN,tr|E5RHC5|E5RHC5_HUMAN" 5 2063.0647 1.65 131418 12118 4 2063.071802 516.7735 ADP-ribosylation factor GTPase-activating protein 1 OS=Homo sapiens OX=9606 GN=ARFGAP1 PE=1 SV=2 5.5 2397.7 - 259540 - - - 3.4265 - 2.398 0.432 - 87.6 1 2 0 0.0071 19 0 0 0 7.07E+07 4.28E+07 - - - 3.28 0.9939 221125_WJC_METTL3_EV_vs_WT_F09.12121.12121.3 0.00629 Oct-44 K.QK[136.11]QNR[166.11]PIPQWIR[166.11].M "sp|P62891|RL39_HUMAN,sp|Q59GN2|R39L5_HUMAN" 2 1590.9101 0.69 131421 12121 3 1590.914162 531.3106 60S ribosomal protein L39 OS=Homo sapiens OX=9606 GN=RPL39 PE=1 SV=2 12.01 2398.1 - 269457 - - - 2.5413 - 2.032 0.301 - 176.7 1 2 1 0.004 12 0 0 0 7.52E+06 1.09E+07 - - - 3.86 1 221125_WJC_METTL3_EV_vs_WT_F09.12122.12122.3 8.73E-09 Oct-72 K.ASELGHSLNENVLKPAQEK.V "sp|Q8N6T3|ARFG1_HUMAN,tr|F8VWH9|F8VWH9_HUMAN,tr|E5RHT6|E5RHT6_HUMAN,tr|F8W1U7|F8W1U7_HUMAN,tr|E5RHC5|E5RHC5_HUMAN" 5 2063.0647 1.74 131422 12122 3 2063.067403 688.6955 ADP-ribosylation factor GTPase-activating protein 1 OS=Homo sapiens OX=9606 GN=ARFGAP1 PE=1 SV=2 5.5 2398.2 - 115731 - - - 1.2942 - 2.563 0.597 - 77.3 1 2 0 0.0027 19 0 0 0 3.03E+07 1.74E+07 - - - 7.5075 0.7768 221125_WJC_METTL3_EV_vs_WT_F09.12125.12125.3 2.51E-05 Oct-80 K.GAQVNAVNQNGC[160.03]TPLHYAASK[136.11].N "sp|O75832|PSD10_HUMAN,tr|B1AJY7|B1AJY7_HUMAN" 2 2207.0633 0.2 131425 12125 3 2208.049674 736.695 26S proteasome non-ATPase regulatory subunit 10 OS=Homo sapiens OX=9606 GN=PSMD10 PE=1 SV=1 8.21 2398.6 - 91421.7 - - - 446.917 - 2.008 0.467 - 117.2 1 2 0 0.9864 21 0 0 0 4.40E+04 2.22E+05 - - - 5.1447 1 221125_WJC_METTL3_EV_vs_WT_F09.12126.12126.3 1.17E-07 Sep-84 K.TK[136.11]PIVK[136.11]PQTSPEYGQGINPISR[166.11].L sp|O95793|STAU1_HUMAN 1 2435.3383 2.2 131426 12126 3 2435.34064 812.7867 Double-stranded RNA-binding protein Staufen homolog 1 OS=Homo sapiens OX=9606 GN=STAU1 PE=1 SV=2 9.7 2398.8 - 77697.5 - - - 0.9695 - 2.322 0.649 - 69 1 2 0 0.0024 22 0 0 0 8.35E+06 3.80E+06 - - - 7.7723 1 221125_WJC_METTL3_EV_vs_WT_F09.12131.12131.3 1.08E-06 24/84 K.TASDVVQPAAVQAQGQVNDENR[166.11].R "sp|Q9BX40|LS14B_HUMAN,tr|Q5TBP9|Q5TBP9_HUMAN,tr|Q5TBQ0|Q5TBQ0_HUMAN" 3 2306.1126 0.42 131429 12131 3 2306.11685 769.7115 Protein LSM14 homolog B OS=Homo sapiens OX=9606 GN=LSM14B PE=1 SV=1 4.03 2399.5 - 360897 - - - 1.8273 - 4.397 0.641 - 683.3 1 2 0 0.0042 22 0 0 0 4.07E+06 9.72E+06 - - - 9.1964 1 221125_WJC_METTL3_EV_vs_WT_F09.12132.12132.4 2.29E-08 20/108 K.ASELGHSLNENVLK[136.11]PAQEK[136.11].V "sp|Q8N6T3|ARFG1_HUMAN,tr|F8VWH9|F8VWH9_HUMAN,tr|E5RHT6|E5RHT6_HUMAN,tr|F8W1U7|F8W1U7_HUMAN,tr|E5RHC5|E5RHC5_HUMAN" 5 2079.0931 1.68 131430 12132 4 2079.098703 520.7806 ADP-ribosylation factor GTPase-activating protein 1 OS=Homo sapiens OX=9606 GN=ARFGAP1 PE=1 SV=2 5.5 2399.6 - 409250 - - - 2.6791 - 3.04 0.583 - 228.7 1 2 0 0.0056 19 0 0 0 7.07E+07 4.20E+07 - - - 4.675 1 221125_WJC_METTL3_EV_vs_WT_F09.12139.12139.3 7.87E-11 17/72 K.ASELGHSLNENVLK[136.11]PAQEK[136.11].V "sp|Q8N6T3|ARFG1_HUMAN,tr|F8VWH9|F8VWH9_HUMAN,tr|E5RHT6|E5RHT6_HUMAN,tr|F8W1U7|F8W1U7_HUMAN,tr|E5RHC5|E5RHC5_HUMAN" 5 2079.0931 1.77 131435 12139 3 2079.095167 694.0383 ADP-ribosylation factor GTPase-activating protein 1 OS=Homo sapiens OX=9606 GN=ARFGAP1 PE=1 SV=2 5.5 2400.7 - 301549 - - - 0.9783 - 3.122 0.658 - 228.9 1 2 0 0.002 19 0 0 0 3.03E+07 1.72E+07 - - - 8.6725 0.9997 221125_WJC_METTL3_EV_vs_WT_F09.12149.12149.4 0.000276 10/114 R.NLHQSGFSLSGSQADDHIAR[166.11].R "sp|O14531|DPYL4_HUMAN,tr|Q5T0Q6|Q5T0Q6_HUMAN" 2 2149.0176 1.04 131443 12149 4 2149.022686 538.2617 Dihydropyrimidinase-related protein 4 OS=Homo sapiens OX=9606 GN=DPYSL4 PE=1 SV=2 5.98 2402.1 - 166009 - - - 2.3606 - 1.803 0.417 - 57 1 2 0 0.0051 20 0 0 0 9.38E+05 8.99E+05 - - - 3.0512 0.9999 221125_WJC_METTL3_EV_vs_WT_F09.12155.12155.3 2.22E-05 Sep-72 R.ESLC[160.03]DSPHQNLSR[166.11]PLLENK[136.11].L "sp|O15042|SR140_HUMAN,tr|U3KPT1|U3KPT1_HUMAN,tr|E7EW00|E7EW00_HUMAN,tr|C9JDJ7|C9JDJ7_HUMAN,tr|E7ET15|E7ET15_HUMAN,tr|H0Y8D9|H0Y8D9_HUMAN,tr|C9J5L1|C9J5L1_HUMAN" 7 2254.1131 0.63 131447 12155 3 2254.110389 752.3783 U2 snRNP-associated SURP motif-containing protein OS=Homo sapiens OX=9606 GN=U2SURP PE=1 SV=2 5.45 2402.9 - 127634 - - - -1.2027 - 2.083 0.472 - 112.2 1 2 0 -0.0027 19 0 0 0 8.34E+05 1.33E+06 - - - 5.6044 0.9997 221125_WJC_METTL3_EV_vs_WT_F09.12157.12157.4 1.81E-08 15/108 R.ESLC[160.03]DSPHQNLSR[166.11]PLLENK[136.11].L "sp|O15042|SR140_HUMAN,tr|U3KPT1|U3KPT1_HUMAN,tr|E7EW00|E7EW00_HUMAN,tr|C9JDJ7|C9JDJ7_HUMAN,tr|E7ET15|E7ET15_HUMAN,tr|H0Y8D9|H0Y8D9_HUMAN,tr|C9J5L1|C9J5L1_HUMAN" 7 2254.1131 0.97 131448 12157 4 2254.118749 564.5356 U2 snRNP-associated SURP motif-containing protein OS=Homo sapiens OX=9606 GN=U2SURP PE=1 SV=2 5.45 2403.1 - 519787 - - - 2.5061 - 3.053 0.399 - 192.3 1 2 0 0.0056 19 0 0 0 5.06E+06 5.22E+06 - - - 3.0749 1 221125_WJC_METTL3_EV_vs_WT_F09.12160.12160.3 9.42E-05 20/84 K.TASDVVQPAAVQAQGQVNDENR.R "sp|Q9BX40|LS14B_HUMAN,tr|Q5TBP9|Q5TBP9_HUMAN,tr|Q5TBQ0|Q5TBQ0_HUMAN" 3 2296.1044 0.42 131451 12160 3 2296.109291 766.3754 Protein LSM14 homolog B OS=Homo sapiens OX=9606 GN=LSM14B PE=1 SV=1 4.03 2403.5 - 291221 - - - 2.1449 - 3.156 0.561 - 347.4 1 2 0 0.0049 22 0 0 0 4.00E+06 9.48E+06 - - - 7.518 0.9995 221125_WJC_METTL3_EV_vs_WT_F09.12186.12186.4 0.000117 13/90 R.SK[136.11]VDEAVAVLQAHHAK[136.11].K "sp|Q13310|PABP4_HUMAN,tr|A0A7I2V5W9|A0A7I2V5W9_HUMAN,tr|H0YEU6|H0YEU6_HUMAN,tr|B1ANR0|B1ANR0_HUMAN,tr|A0A7I2V4L7|A0A7I2V4L7_HUMAN,tr|H0YER0|H0YER0_HUMAN,tr|A0A7I2V598|A0A7I2V598_HUMAN,tr|A0A7I2V4V6|A0A7I2V4V6_HUMAN,tr|H0Y5F5|H0Y5F5_HUMAN,tr|H0Y6X6|H0Y6X6_HUMAN" 10 1717.9446 1.45 131469 12186 4 1717.948263 430.4934 Polyadenylate-binding protein 4 OS=Homo sapiens OX=9606 GN=PABPC4 PE=1 SV=1 6.66 2407.2 - 186718 - - - 2.1217 - 2.457 0.448 - 129.5 1 2 1 0.0036 16 0 0 0 5.39E+06 3.72E+06 - - - 3.441 1 221125_WJC_METTL3_EV_vs_WT_F09.12198.12198.3 6.02E-14 20/60 K.HNMDIGTWDNKGPVAK.A sp|Q9Y5A9|YTHD2_HUMAN 1 1781.8519 1.35 131477 12198 3 1781.856897 594.9579 YTH domain-containing family protein 2 OS=Homo sapiens OX=9606 GN=YTHDF2 PE=1 SV=2 6.75 2408.9 - 738833 - - - 2.8027 - 3.679 0.721 - 537 1 2 1 0.005 16 0 0 0 3.25E+07 2.41E+07 - - - 9.9195 0.9997 221125_WJC_METTL3_EV_vs_WT_F09.12202.12202.3 5.85E-06 13/60 R.SKVDEAVAVLQAHHAK.K "sp|Q13310|PABP4_HUMAN,tr|A0A7I2V5W9|A0A7I2V5W9_HUMAN,tr|H0YEU6|H0YEU6_HUMAN,tr|B1ANR0|B1ANR0_HUMAN,tr|A0A7I2V4L7|A0A7I2V4L7_HUMAN,tr|H0YER0|H0YER0_HUMAN,tr|A0A7I2V598|A0A7I2V598_HUMAN,tr|A0A7I2V4V6|A0A7I2V4V6_HUMAN,tr|H0Y5F5|H0Y5F5_HUMAN,tr|H0Y6X6|H0Y6X6_HUMAN" 10 1701.9162 1.47 131481 12202 3 1701.920075 568.3127 Polyadenylate-binding protein 4 OS=Homo sapiens OX=9606 GN=PABPC4 PE=1 SV=1 6.66 2409.4 - 137527 - - - 2.2663 - 2.422 0.522 - 166.1 1 2 1 0.0039 16 0 0 0 1.61E+06 1.09E+06 - - - 6.6285 1 221125_WJC_METTL3_EV_vs_WT_F09.12209.12209.4 3.05E-10 17/90 K.HNMDIGTWDNKGPVAK.A sp|Q9Y5A9|YTHD2_HUMAN 1 1781.8519 1.1 131486 12209 4 1781.857749 446.4703 YTH domain-containing family protein 2 OS=Homo sapiens OX=9606 GN=YTHDF2 PE=1 SV=2 6.75 2410.3 - 381802 - - - 3.2809 - 3.073 0.631 - 245.3 1 2 1 0.0058 16 0 0 0 7.38E+06 6.73E+06 - - - 5.1121 0.9994 221125_WJC_METTL3_EV_vs_WT_F09.12211.12211.3 0.00257 Jul-60 R.DGTGHYLC[160.03]NAC[160.03]GLYHK.M "sp|P23771|GATA3_HUMAN,sp|P23769|GATA2_HUMAN,sp|P43694|GATA4_HUMAN,sp|Q9BWX5|GATA5_HUMAN,tr|E9PKS4|E9PKS4_HUMAN,tr|B3KUF4|B3KUF4_HUMAN,tr|A0A087WZ09|A0A087WZ09_HUMAN" 7 1864.7985 2.71 131488 12211 3 1864.804469 622.6068 Trans-acting T-cell-specific transcription factor GATA-3 OS=Homo sapiens OX=9606 GN=GATA3 PE=1 SV=1 6.9 2410.6 - 108018 - - - 3.2073 - 1.532 0.47 - 59.1 1 2 0 0.006 16 0 0 0 1.26E+06 4.64E+05 - - - 4.8729 0.9999 221125_WJC_METTL3_EV_vs_WT_F09.12214.12214.3 1.11E-07 14/88 R.QPPPAPPEQADGNAPGPQPPPVR.L sp|Q12948|FOXC1_HUMAN 1 2313.1502 6.46 131490 12214 3 2313.158262 772.0573 Forkhead box protein C1 OS=Homo sapiens OX=9606 GN=FOXC1 PE=1 SV=3 4.37 2411.1 - 202698 - - - 3.4879 - 2.617 0.583 - 133.4 1 2 0 0.0081 23 0 0 0 7.49E+06 1.16E+06 - - - 7.2945 0.9993 221125_WJC_METTL3_EV_vs_WT_F09.12221.12221.3 0.000905 Oct-72 K.IHVSDQELQSANASVDDSR.L "sp|P22314|UBA1_HUMAN,tr|Q5JRR6|Q5JRR6_HUMAN" 2 2069.9614 0.69 131496 12221 3 2069.954908 690.9944 Ubiquitin-like modifier-activating enzyme 1 OS=Homo sapiens OX=9606 GN=UBA1 PE=1 SV=3 4.22 2412 - 116834 - - - -3.1315 - 2.371 0.359 - 122.1 1 2 0 -0.0065 19 0 0 0 2.22E+06 3.20E+06 - - - 4.6617 0.9996 221125_WJC_METTL3_EV_vs_WT_F09.12222.12222.3 0.135 Jul-92 R.QLQGLAAPEAGTQEEQEDQEPR[166.11]PR[166.11].R "sp|Q8NFI3|ENASE_HUMAN,tr|J3QLG5|J3QLG5_HUMAN" 2 2696.2905 0.53 131497 12222 3 2696.293993 899.7708 Cytosolic endo-beta-N-acetylglucosaminidase OS=Homo sapiens OX=9606 GN=ENGASE PE=1 SV=1 4.14 2412.1 - 48560.1 - - - 1.2992 - 1.754 0.394 - 38.5 1 2 0 0.0035 24 0 0 0 3.22E+05 6.06E+05 - - - 4.2368 1 221125_WJC_METTL3_EV_vs_WT_F09.12227.12227.4 5.33E-11 20/126 K.HGAPSPSHPISAPQAAAAAALR.R "sp|P35658|NU214_HUMAN,tr|A0A0A0MSW3|A0A0A0MSW3_HUMAN,tr|H0YF36|H0YF36_HUMAN,tr|A0A494C1F2|A0A494C1F2_HUMAN" 4 2077.0817 15.77 131500 12227 4 2077.088241 520.2777 Nuclear pore complex protein Nup214 OS=Homo sapiens OX=9606 GN=NUP214 PE=1 SV=2 9.76 2412.8 - 375883 - - - 3.1395 - 3.573 0.623 - 303.6 1 2 0 0.0065 22 0 0 0 3.45E+07 2.19E+06 - - - 5.0634 1 221125_WJC_METTL3_EV_vs_WT_F09.12228.12228.3 7.86E-14 19/68 K.NQDEC[160.03]VIALHDC[160.03]NGDVNR.A "sp|Q14157|UBP2L_HUMAN,tr|Q5VU78|Q5VU78_HUMAN,tr|F8W726|F8W726_HUMAN,tr|Q5VU81|Q5VU81_HUMAN,tr|Q5VU79|Q5VU79_HUMAN,tr|Q5VU80|Q5VU80_HUMAN,tr|Q5VU77|Q5VU77_HUMAN" 7 2127.9062 2.32 131501 12228 3 2127.910704 710.3093 Ubiquitin-associated protein 2-like OS=Homo sapiens OX=9606 GN=UBAP2L PE=1 SV=2 4.22 2413 - 345269 - - - 2.1166 - 3.989 0.658 - 574.7 1 2 0 0.0045 18 0 0 0 1.05E+08 4.53E+07 - - - 9.32 0.9999 221125_WJC_METTL3_EV_vs_WT_F09.12229.12229.4 2.90E-09 16/126 K.HGAPSPSHPISAPQAAAAAALR[166.11].R "sp|P35658|NU214_HUMAN,tr|A0A0A0MSW3|A0A0A0MSW3_HUMAN,tr|H0YF36|H0YF36_HUMAN,tr|A0A494C1F2|A0A494C1F2_HUMAN" 4 2087.09 2.65 131502 12229 4 2087.096136 522.7798 Nuclear pore complex protein Nup214 OS=Homo sapiens OX=9606 GN=NUP214 PE=1 SV=2 9.76 2413.1 - 148911 - - - 2.9448 - 3.152 0.573 - 172.5 1 2 0 0.0061 22 0 0 0 4.13E+07 1.56E+07 - - - 4.5873 1 221125_WJC_METTL3_EV_vs_WT_F09.12238.12238.3 4.13E-09 24/84 K.HGAPSPSHPISAPQAAAAAALR.R "sp|P35658|NU214_HUMAN,tr|A0A0A0MSW3|A0A0A0MSW3_HUMAN,tr|H0YF36|H0YF36_HUMAN,tr|A0A494C1F2|A0A494C1F2_HUMAN" 4 2077.0817 39.18 131509 12238 3 2077.085781 693.3678 Nuclear pore complex protein Nup214 OS=Homo sapiens OX=9606 GN=NUP214 PE=1 SV=2 9.76 2414.2 - 165107 - - - 1.9551 - 4 0.658 - 622.4 1 2 0 0.0041 22 0 0 0 1.63E+07 4.16E+05 - - - 9.1616 1 221125_WJC_METTL3_EV_vs_WT_F09.12250.12250.3 4.86E-11 17/68 K.NEAIQAAHDAVAQEGQC[160.03]R.V "sp|P09936|UCHL1_HUMAN,tr|D6R956|D6R956_HUMAN,tr|D6R974|D6R974_HUMAN" 3 1966.8915 0.87 131519 12250 3 1966.898854 656.6378 Ubiquitin carboxyl-terminal hydrolase isozyme L1 OS=Homo sapiens OX=9606 GN=UCHL1 PE=1 SV=2 4.65 2415.9 - 256853 - - - 3.7206 - 3.367 0.678 - 389.2 1 2 0 0.0073 18 0 0 0 6.94E+06 7.95E+06 - - - 9.12 0.7662 221125_WJC_METTL3_EV_vs_WT_F09.12252.12252.4 0.0448 Nov-78 R.K[136.11]IELFGR[166.11]PHNVQPN.W sp|Q86U44|MTA70_HUMAN 1 1665.907 0.04 131521 12252 4 1665.909642 417.484 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 8.75 2416.1 - 187385 - - - 1.5895 - 1.979 0.262 - 106.7 1 1 0 0.0026 14 0 0 0 2.63E+05 6.63E+06 - - - 1.7541 0.9998 221125_WJC_METTL3_EV_vs_WT_F09.12253.12253.4 0.000137 8/120 K.TESSGIETEPTVHHLPLSTEK[136.11].V "sp|Q9Y2J2|E41L3_HUMAN,tr|A0A0A0MRA8|A0A0A0MRA8_HUMAN,tr|A8K968|A8K968_HUMAN,tr|A0A0J9YY18|A0A0J9YY18_HUMAN,tr|A0A0A0MSA4|A0A0A0MSA4_HUMAN,tr|A0A0J9YW31|A0A0J9YW31_HUMAN" 6 2299.1423 0.89 131522 12253 4 2299.147983 575.7929 Band 4.1-like protein 3 OS=Homo sapiens OX=9606 GN=EPB41L3 PE=1 SV=2 4.87 2416.3 - 127547 - - - 2.4627 - 1.778 0.458 - 33 1 2 0 0.0057 21 0 0 0 7.43E+06 8.33E+06 - - - 3.4011 0.9802 221125_WJC_METTL3_EV_vs_WT_F09.12254.12254.2 0.000313 28-Sep E.LALTQSVGGDSSADR[166.11].L "sp|Q86U44|MTA70_HUMAN,tr|H0YFV6|H0YFV6_HUMAN" 2 1485.7299 0.001 131523 12254 2 1485.732044 743.8722 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 4.21 2416.4 - 106587 - - - 1.4633 - 1.956 0.459 - 279.8 1 1 0 0.0022 15 0 0 0 0.00E+00 5.05E+06 - - - 4.0799 0.8875 221125_WJC_METTL3_EV_vs_WT_F09.12258.12258.3 0.181 7/104 K.ASASGSGAQVGGPISSGSSASSVTVTR.S "sp|P02545|LMNA_HUMAN,tr|A0A6Q8PFJ0|A0A6Q8PFJ0_HUMAN" 2 2364.1517 2.92 131527 12258 3 2364.150539 789.0578 Prelamin-A\C OS=Homo sapiens OX=9606 GN=LMNA PE=1 SV=1 9.79 2416.9 - 197316 - - - -0.4953 - 1.278 0.114 - 27.2 1 2 0 -0.0012 27 0 0 0 3.53E+05 1.21E+05 - - - 0.375 1 221125_WJC_METTL3_EV_vs_WT_F09.12259.12259.3 1.57E-07 7/104 K.AEAGPESAAGGQEEEEGEDEEELSGTK.V "sp|Q8N5A5|ZGPAT_HUMAN,tr|V9GY48|V9GY48_HUMAN" 2 2734.1213 3.89 131528 12259 3 2734.120668 912.381 Zinc finger CCCH-type with G patch domain-containing protein OS=Homo sapiens OX=9606 GN=ZGPAT PE=1 SV=3 3.59 2417.1 - 55448.6 - - - -0.2374 - 1.833 0.649 - 32.1 1 2 0 -0.0006 27 0 0 0 7.48E+05 1.92E+05 - - - 7.1696 0.9992 221125_WJC_METTL3_EV_vs_WT_F09.12264.12264.4 4.51E-05 13/96 K.KTGQPMINLYTDRETGK.L "sp|P35637|FUS_HUMAN,tr|H3BPE7|H3BPE7_HUMAN" 2 1950.9833 0.94 131531 12264 4 1950.988827 488.7531 RNA-binding protein FUS OS=Homo sapiens OX=9606 GN=FUS PE=1 SV=1 8.5 2417.7 - 236432 - - - 2.8273 - 2.611 0.44 - 132.9 1 2 1 0.0055 17 0 0 0 9.17E+06 9.71E+06 - - - 3.3874 0.9898 221125_WJC_METTL3_EV_vs_WT_F09.12268.12268.3 0.016 Jul-64 K.KTGQPMINLYTDRETGK.L "sp|P35637|FUS_HUMAN,tr|H3BPE7|H3BPE7_HUMAN" 2 1950.9833 1.02 131535 12268 3 1950.988476 651.335 RNA-binding protein FUS OS=Homo sapiens OX=9606 GN=FUS PE=1 SV=1 8.5 2418.2 - 108683 - - - 2.6474 - 1.745 0.321 - 64.8 1 2 1 0.0052 17 0 0 0 3.98E+06 3.91E+06 - - - 3.5239 1 221125_WJC_METTL3_EV_vs_WT_F09.12269.12269.2 2.32E-05 Jun-34 K.NQDEC[160.03]VIALHDC[160.03]NGDVNR.A "sp|Q14157|UBP2L_HUMAN,tr|Q5VU78|Q5VU78_HUMAN,tr|F8W726|F8W726_HUMAN,tr|Q5VU81|Q5VU81_HUMAN,tr|Q5VU79|Q5VU79_HUMAN,tr|Q5VU80|Q5VU80_HUMAN,tr|Q5VU77|Q5VU77_HUMAN" 7 2127.9062 6.64 131536 12269 2 2127.909901 1064.9604 Ubiquitin-associated protein 2-like OS=Homo sapiens OX=9606 GN=UBAP2L PE=1 SV=2 4.22 2418.3 - 39531.9 - - - 1.7393 - 1.773 0.72 - 73.5 1 2 0 0.0037 18 0 0 0 5.51E+05 8.30E+04 - - - 5.7657 1 221125_WJC_METTL3_EV_vs_WT_F09.12281.12281.3 3.29E-10 17/84 K.HGAPSPSHPISAPQAAAAAALR[166.11].R "sp|P35658|NU214_HUMAN,tr|A0A0A0MSW3|A0A0A0MSW3_HUMAN,tr|H0YF36|H0YF36_HUMAN,tr|A0A494C1F2|A0A494C1F2_HUMAN" 4 2087.09 4.15 131544 12281 3 2087.095531 696.7039 Nuclear pore complex protein Nup214 OS=Homo sapiens OX=9606 GN=NUP214 PE=1 SV=2 9.76 2420 - 144111 - - - 2.6549 - 3.504 0.672 - 270.1 1 2 0 0.0055 22 0 0 0 3.68E+07 8.87E+06 - - - 9.0034 0.9992 221125_WJC_METTL3_EV_vs_WT_F09.12286.12286.2 0.00891 16-Aug R.SLVNLGGSK.S sp|P04264|K2C1_HUMAN 1 873.492 999 131547 12286 2 873.494064 437.7533 "Keratin, type II cytoskeletal 1 OS=Homo sapiens OX=9606 GN=KRT1 PE=1 SV=6" 8.47 2420.7 - 477896 - - - 2.3835 - 1.518 0.478 - 192.8 1 2 0 0.0021 9 0 0 0 7.17E+06 0.00E+00 - - - 3.7784 0.9999 221125_WJC_METTL3_EV_vs_WT_F09.12287.12287.4 1.00E-06 17/96 K.K[136.11]TGQPMINLYTDR[166.11]ETGK[136.11].L "sp|P35637|FUS_HUMAN,tr|H3BPE7|H3BPE7_HUMAN" 2 1977.02 0.95 131548 12287 4 1977.019056 495.2623 RNA-binding protein FUS OS=Homo sapiens OX=9606 GN=FUS PE=1 SV=1 8.5 2420.9 - 369985 - - - -0.4679 - 2.943 0.532 - 258.1 1 2 1 -0.0009 17 0 0 0 9.18E+06 9.64E+06 - - - 4.231 0.9998 221125_WJC_METTL3_EV_vs_WT_F09.12293.12293.4 6.69E-07 11/114 K.ASLSYEEGHPSHSETDLLQR.Q "tr|A0A3B3IRW6|A0A3B3IRW6_HUMAN,tr|A0A3B3ISY4|A0A3B3ISY4_HUMAN" 2 2255.0455 3.25 131552 12293 4 2255.054589 564.7686 Glutamine and serine-rich protein 1 OS=Homo sapiens OX=9606 GN=QSER1 PE=1 SV=1 4.8 2421.7 - 178885 - - - 4.0509 - 2.486 0.538 - 72.6 1 2 0 0.0091 20 0 0 0 8.45E+06 2.60E+06 - - - 4.2107 0.9996 221125_WJC_METTL3_EV_vs_WT_F09.12294.12294.4 7.04E-05 8/120 K.TESSGIETEPTVHHLPLSTEK.V "sp|Q9Y2J2|E41L3_HUMAN,tr|A0A0A0MRA8|A0A0A0MRA8_HUMAN,tr|A8K968|A8K968_HUMAN,tr|A0A0J9YY18|A0A0J9YY18_HUMAN,tr|A0A0A0MSA4|A0A0A0MSA4_HUMAN,tr|A0A0J9YW31|A0A0J9YW31_HUMAN" 6 2291.1281 0.86 131553 12294 4 2291.135506 573.7893 Band 4.1-like protein 3 OS=Homo sapiens OX=9606 GN=EPB41L3 PE=1 SV=2 4.87 2421.8 - 236915 - - - 3.2233 - 2.002 0.423 - 38.5 1 2 0 0.0074 21 0 0 0 7.17E+06 8.31E+06 - - - 3.1353 0.9982 221125_WJC_METTL3_EV_vs_WT_F09.12295.12295.4 0.00889 Aug-78 K.K[136.11]HPDSSVNFAEFSK[136.11].K "sp|P26583|HMGB2_HUMAN,tr|D6R9A6|D6R9A6_HUMAN" 2 1607.7915 0.24 131554 12295 4 1607.793966 402.9551 High mobility group protein B2 OS=Homo sapiens OX=9606 GN=HMGB2 PE=1 SV=2 6.75 2422 - 175794 - - - 1.5518 - 1.438 0.291 - 37.1 1 2 0 0.0025 14 0 0 0 2.64E+06 1.08E+07 - - - 1.8904 1 221125_WJC_METTL3_EV_vs_WT_F09.12302.12302.3 2.58E-09 15/68 K.NEAIQAAHDAVAQEGQC[160.03]R[166.11].V "sp|P09936|UCHL1_HUMAN,tr|D6R956|D6R956_HUMAN,tr|D6R974|D6R974_HUMAN" 3 1976.8998 0.87 131560 12302 3 1976.90237 659.9739 Ubiquitin carboxyl-terminal hydrolase isozyme L1 OS=Homo sapiens OX=9606 GN=UCHL1 PE=1 SV=2 4.65 2422.9 - 239880 - - - 1.297 - 3.083 0.55 - 298.7 1 2 0 0.0026 18 0 0 0 6.94E+06 7.95E+06 - - - 7.4749 1 221125_WJC_METTL3_EV_vs_WT_F09.12314.12314.3 2.54E-13 15/100 R.NEGQLNGETNTPIEGNQAGDAAASAR.S "sp|P18583|SON_HUMAN,tr|J3QSZ5|J3QSZ5_HUMAN" 2 2584.175 -1 131569 12314 3 2585.163647 862.3989 Protein SON OS=Homo sapiens OX=9606 GN=SON PE=1 SV=4 4 2424.5 - 141514 - - - 382.5914 - 3.368 0.73 - 211.4 1 2 0 0.9887 26 0 0 0 0.00E+00 0.00E+00 - - - 9.1986 0.9814 221125_WJC_METTL3_EV_vs_WT_F09.12316.12316.3 4.49E-07 11/100 R.NEGQLNGETNTPIEGNQAGDAAASAR[166.11].S "sp|P18583|SON_HUMAN,tr|J3QSZ5|J3QSZ5_HUMAN" 2 2594.1832 0.12 131571 12316 3 2595.169696 865.735 Protein SON OS=Homo sapiens OX=9606 GN=SON PE=1 SV=4 4 2424.7 - 85066 - - - 380.2592 - 2.469 0.651 - 95.7 1 2 0 0.9865 26 0 0 0 4.06E+04 3.49E+05 - - - 7.6041 1 221125_WJC_METTL3_EV_vs_WT_F09.12322.12322.3 3.47E-08 14/52 K.KHPDSSVNFAEFSK.K "sp|P26583|HMGB2_HUMAN,tr|D6R9A6|D6R9A6_HUMAN" 2 1591.7631 0.22 131575 12322 3 1591.765963 531.595 High mobility group protein B2 OS=Homo sapiens OX=9606 GN=HMGB2 PE=1 SV=2 6.75 2425.6 - 537502 - - - 1.8169 - 2.853 0.597 - 282.5 1 2 0 0.0029 14 0 0 0 1.59E+07 7.13E+07 - - - 7.9812 1 221125_WJC_METTL3_EV_vs_WT_F09.12331.12331.2 4.36E-05 17/40 K.SPAVATSTAAPPPPSSPLPSK.S "sp|Q14157|UBP2L_HUMAN,tr|F8W726|F8W726_HUMAN" 2 1959.0313 4.25 131582 12331 2 1959.026278 980.5229 Ubiquitin-associated protein 2-like OS=Homo sapiens OX=9606 GN=UBAP2L PE=1 SV=2 8.47 2426.8 - 75704.4 - - - -2.5671 - 3.787 0.668 - 438.2 1 2 0 -0.005 21 0 0 0 5.23E+06 1.23E+06 - - - 7.247 0.9978 221125_WJC_METTL3_EV_vs_WT_F09.12336.12336.3 0.000159 Jun-72 K.K[136.11]LGEMWNNTAADDK[136.11]QPYEK[136.11].K "sp|P09429|HMGB1_HUMAN,tr|Q5T7C4|Q5T7C4_HUMAN" 2 2261.0849 0.21 131585 12336 3 2261.086672 754.7022 High mobility group protein B1 OS=Homo sapiens OX=9606 GN=HMGB1 PE=1 SV=3 4.78 2427.5 - 185391 - - - 0.7912 - 1.655 0.368 - 28.8 1 2 1 0.0018 19 0 0 0 4.97E+05 2.31E+06 - - - 3.8801 0.9593 221125_WJC_METTL3_EV_vs_WT_F09.12337.12337.3 0.295 May-76 K.NNALVPGTIQVNGHGGQPSK[136.11].L sp|Q8WWQ0|PHIP_HUMAN 1 1995.0377 2 131586 12337 3 1995.038175 666.0199 PH-interacting protein OS=Homo sapiens OX=9606 GN=PHIP PE=1 SV=2 8.76 2427.6 - 55746.6 - - - 0.22 - 1.074 0.203 - 28.4 1 2 0 0.0004 20 0 0 0 1.55E+06 7.75E+05 - - - 0.9763 0.9986 221125_WJC_METTL3_EV_vs_WT_F09.12344.12344.3 0.000248 Aug-44 K.TGNLGNVVHIER.F "sp|Q6P5R6|RL22L_HUMAN,tr|H0Y8C2|H0Y8C2_HUMAN,tr|C9JYQ9|C9JYQ9_HUMAN" 3 1307.6946 0.78 131591 12344 3 1307.699353 436.9055 60S ribosomal protein L22-like 1 OS=Homo sapiens OX=9606 GN=RPL22L1 PE=1 SV=2 6.41 2428.6 - 114195 - - - 3.6362 - 1.498 0.429 - 64.3 1 2 0 0.0048 12 0 0 0 8.27E+05 1.06E+06 - - - 4.4418 0.9998 221125_WJC_METTL3_EV_vs_WT_F09.12346.12346.2 8.53E-05 May-32 R.TDYNASVSVPDSSGPER[166.11].L "sp|P61978|HNRPK_HUMAN,tr|Q5T6W2|Q5T6W2_HUMAN" 2 1789.7994 1.63 131593 12346 2 1789.798729 895.907 Heterogeneous nuclear ribonucleoprotein K OS=Homo sapiens OX=9606 GN=HNRNPK PE=1 SV=1 4.03 2428.8 - 78371.6 - - - -0.3783 - 1.539 0.526 - 51.7 1 2 0 -0.0007 17 0 0 0 2.16E+06 1.32E+06 - - - 3.9858 1 221125_WJC_METTL3_EV_vs_WT_F09.12351.12351.3 6.99E-12 20/92 R.RVENSIPAAGETQNVEVAAGPAGK.C "sp|Q15020|SART3_HUMAN,tr|A0A499FI31|A0A499FI31_HUMAN" 2 2364.2034 5.65 131596 12351 3 2364.205552 789.0751 Squamous cell carcinoma antigen recognized by T-cells 3 OS=Homo sapiens OX=9606 GN=SART3 PE=1 SV=1 4.79 2429.5 - 603868 - - - 0.931 - 4.164 0.687 - 377.4 1 2 0 0.0022 24 0 0 0 4.20E+07 7.43E+06 - - - 9.5119 0.9996 221125_WJC_METTL3_EV_vs_WT_F09.12353.12353.3 4.02E-05 Jun-88 R.C[160.03]VAC[160.03]QNPDKPSPSTSVPAPASFK.F sp|P49792|RBP2_HUMAN 1 2444.1464 1.13 131598 12353 3 2444.146331 815.7228 E3 SUMO-protein ligase RanBP2 OS=Homo sapiens OX=9606 GN=RANBP2 PE=1 SV=2 8.05 2429.8 - 123355 - - - -0.0409 - 1.404 0.418 - 27.7 1 2 0 -0.0001 23 0 0 0 1.18E+07 1.04E+07 - - - 3.9963 1 221125_WJC_METTL3_EV_vs_WT_F09.12354.12354.3 3.38E-07 16/80 K.SPAVATSTAAPPPPSSPLPSK.S "sp|Q14157|UBP2L_HUMAN,tr|F8W726|F8W726_HUMAN" 2 1959.0313 6.82 131599 12354 3 1959.032006 654.0177 Ubiquitin-associated protein 2-like OS=Homo sapiens OX=9606 GN=UBAP2L PE=1 SV=2 8.47 2429.9 - 111392 - - - 0.3568 - 3.118 0.468 - 287.7 1 2 0 0.0007 21 0 0 0 4.05E+06 5.94E+05 - - - 6.4839 0.9998 221125_WJC_METTL3_EV_vs_WT_F09.12358.12358.3 3.24E-08 13/92 R.R[166.11]VENSIPAAGETQNVEVAAGPAGK[136.11].C "sp|Q15020|SART3_HUMAN,tr|A0A499FI31|A0A499FI31_HUMAN" 2 2382.2258 5.63 131601 12358 3 2382.214437 795.0826 Squamous cell carcinoma antigen recognized by T-cells 3 OS=Homo sapiens OX=9606 GN=SART3 PE=1 SV=1 4.79 2430.4 - 171900 - - - -4.7787 - 2.948 0.606 - 142.6 1 2 0 -0.0114 24 0 0 0 4.18E+07 7.43E+06 - - - 7.8042 0.9999 221125_WJC_METTL3_EV_vs_WT_F09.12359.12359.2 7.19E-05 Aug-32 R.TDYNASVSVPDSSGPER.L "sp|P61978|HNRPK_HUMAN,tr|Q5T6W2|Q5T6W2_HUMAN" 2 1779.7911 1.63 131602 12359 2 1779.790827 890.9028 Heterogeneous nuclear ribonucleoprotein K OS=Homo sapiens OX=9606 GN=HNRNPK PE=1 SV=1 4.03 2430.6 - 115407 - - - -0.1736 - 1.752 0.617 - 117.3 1 2 0 -0.0003 17 0 0 0 2.16E+06 1.32E+06 - - - 4.9767 1 221125_WJC_METTL3_EV_vs_WT_F09.12387.12387.4 1.44E-08 14/84 R.NHDHQEIAVPVANLK[136.11].L sp|O75607|NPM3_HUMAN 1 1691.8835 1.05 131619 12387 4 1691.882898 423.9781 Nucleoplasmin-3 OS=Homo sapiens OX=9606 GN=NPM3 PE=1 SV=3 5.99 2434.3 - 163926 - - - -0.3369 - 2.6 0.607 - 167.3 1 2 0 -0.0006 15 0 0 0 1.75E+07 1.66E+07 - - - 4.8511 1 221125_WJC_METTL3_EV_vs_WT_F09.12388.12388.3 1.28E-09 16/56 R.NHDHQEIAVPVANLK[136.11].L sp|O75607|NPM3_HUMAN 1 1691.8835 1.08 131620 12388 3 1691.882888 564.9684 Nucleoplasmin-3 OS=Homo sapiens OX=9606 GN=NPM3 PE=1 SV=3 5.99 2434.5 - 487016 - - - -0.3428 - 2.991 0.508 - 357.5 1 2 0 -0.0006 15 0 0 0 4.69E+07 4.36E+07 - - - 7.0624 0.9997 221125_WJC_METTL3_EV_vs_WT_F09.12392.12392.4 0.00344 13/96 R.GRSEADSDKNATILELR.S sp|P15924|DESP_HUMAN 1 1873.9494 10.36 131622 12392 4 1873.951269 469.4946 Desmoplakin OS=Homo sapiens OX=9606 GN=DSP PE=1 SV=3 4.78 2435 - 150693 - - - 1.0144 - 2.435 0.444 - 170.7 1 2 2 0.0019 17 0 0 0 1.62E+07 1.56E+06 - - - 3.399 1 221125_WJC_METTL3_EV_vs_WT_F09.12394.12394.4 4.22E-12 16/84 R.NHDHQEIAVPVANLK.L sp|O75607|NPM3_HUMAN 1 1683.8693 1.05 131623 12394 4 1683.868849 421.9746 Nucleoplasmin-3 OS=Homo sapiens OX=9606 GN=NPM3 PE=1 SV=3 5.99 2435.3 - 277905 - - - -0.2488 - 3.303 0.625 - 256.1 1 2 0 -0.0004 15 0 0 0 1.75E+07 1.66E+07 - - - 5.0934 1 221125_WJC_METTL3_EV_vs_WT_F09.12402.12402.3 3.17E-06 18/56 R.NHDHQEIAVPVANLK.L sp|O75607|NPM3_HUMAN 1 1683.8693 1.07 131627 12402 3 1683.87161 562.297 Nucleoplasmin-3 OS=Homo sapiens OX=9606 GN=NPM3 PE=1 SV=3 5.99 2436.4 - 1.03E+06 - - - 1.3908 - 3.57 0.615 - 499.1 1 2 0 0.0023 15 0 0 0 4.69E+07 4.37E+07 - - - 8.7166 0.9999 221125_WJC_METTL3_EV_vs_WT_F09.12409.12409.3 7.83E-06 13/64 R.GRSEADSDKNATILELR.S sp|P15924|DESP_HUMAN 1 1873.9494 24.12 131631 12409 3 1873.952971 625.6571 Desmoplakin OS=Homo sapiens OX=9606 GN=DSP PE=1 SV=3 4.78 2437.4 - 235585 - - - 1.9227 - 2.559 0.585 - 286.9 1 2 2 0.0036 17 0 0 0 1.15E+07 4.78E+05 - - - 7.4349 1 221125_WJC_METTL3_EV_vs_WT_F09.12410.12410.3 2.21E-07 10/124 R.ALQRPSAAAPQAENGPAAAPAVAAPAATEAPK.M "sp|Q15020|SART3_HUMAN,tr|A0A499FI31|A0A499FI31_HUMAN" 2 2964.5417 4.53 131632 12410 3 2964.540466 989.1879 Squamous cell carcinoma antigen recognized by T-cells 3 OS=Homo sapiens OX=9606 GN=SART3 PE=1 SV=1 6.19 2437.5 - 88183.5 - - - -0.4274 - 2.533 0.563 - 46 1 2 0 -0.0013 32 0 0 0 2.86E+07 6.31E+06 - - - 6.9548 1 221125_WJC_METTL3_EV_vs_WT_F09.12415.12415.3 2.81E-06 Dec-76 K.ASESSKPWPDATYGTGSASR.A "sp|Q9Y2W1|TR150_HUMAN,tr|A0A3B3ITZ9|A0A3B3ITZ9_HUMAN" 2 2053.9341 2.92 131635 12415 3 2053.932293 685.652 Thyroid hormone receptor-associated protein 3 OS=Homo sapiens OX=9606 GN=THRAP3 PE=1 SV=2 6.11 2438.2 - 178087 - - - -0.8856 - 2.49 0.513 - 141.3 1 2 0 -0.0018 20 0 0 0 1.05E+07 3.61E+06 - - - 6.4722 0.9997 221125_WJC_METTL3_EV_vs_WT_F09.12417.12417.3 1.16E-05 Nov-68 K.NQDEC[160.03]VIALHDC[160.03]NGDVNR[166.11].A "sp|Q14157|UBP2L_HUMAN,tr|Q5VU78|Q5VU78_HUMAN,tr|F8W726|F8W726_HUMAN,tr|Q5VU81|Q5VU81_HUMAN,tr|Q5VU79|Q5VU79_HUMAN,tr|Q5VU80|Q5VU80_HUMAN,tr|Q5VU77|Q5VU77_HUMAN" 7 2137.9145 2.71 131637 12417 3 2138.915765 713.6454 Ubiquitin-associated protein 2-like OS=Homo sapiens OX=9606 GN=UBAP2L PE=1 SV=2 4.22 2438.4 - 80101.7 - - - 468.3513 - 2.724 0.657 - 186.1 1 2 0 1.0013 18 0 0 0 3.80E+06 1.40E+06 - - - 8.0829 0.8912 221125_WJC_METTL3_EV_vs_WT_F09.12426.12426.3 0.00012 Jul-72 K.TEELNKEVASNSELVQSSR.S "sp|P08779|K1C16_HUMAN,tr|K7ENW6|K7ENW6_HUMAN" 2 2119.0393 83.2 131644 12426 3 2120.031692 707.3537 "Keratin, type I cytoskeletal 16 OS=Homo sapiens OX=9606 GN=KRT16 PE=1 SV=4" 4.49 2439.7 - 86389.1 - - - 468.3188 - 1.851 0.549 - 57.2 1 2 1 0.9924 19 0 0 0 1.35E+06 1.62E+04 - - - 5.8986 1 221125_WJC_METTL3_EV_vs_WT_F09.12434.12434.3 4.16E-07 11/124 R.ALQR[166.11]PSAAAPQAENGPAAAPAVAAPAATEAPK[136.11].M "sp|Q15020|SART3_HUMAN,tr|A0A499FI31|A0A499FI31_HUMAN" 2 2982.5642 4.52 131650 12434 3 2982.564489 995.1953 Squamous cell carcinoma antigen recognized by T-cells 3 OS=Homo sapiens OX=9606 GN=SART3 PE=1 SV=1 6.19 2440.8 - 103120 - - - 0.0959 - 2.354 0.557 - 50.2 1 2 0 0.0003 32 0 0 0 2.85E+07 6.31E+06 - - - 6.7195 1 221125_WJC_METTL3_EV_vs_WT_F09.12438.12438.4 7.35E-14 29/186 R.ALQRPSAAAPQAENGPAAAPAVAAPAATEAPK.M "sp|Q15020|SART3_HUMAN,tr|A0A499FI31|A0A499FI31_HUMAN" 2 2964.5417 3.75 131652 12438 4 2964.552039 742.1427 Squamous cell carcinoma antigen recognized by T-cells 3 OS=Homo sapiens OX=9606 GN=SART3 PE=1 SV=1 6.19 2441.4 - 778114 - - - 3.4764 - 5.63 0.683 - 366.5 1 2 0 0.0103 32 0 0 0 2.08E+07 5.55E+06 - - - 5.6898 0.9992 221125_WJC_METTL3_EV_vs_WT_F09.12439.12439.4 0.00116 Jul-96 K.MDLSESSKPLQQHLTTK.G "sp|Q2KHR3|QSER1_HUMAN,tr|A0A3B3IRW6|A0A3B3IRW6_HUMAN" 2 1941.983 0.88 131653 12439 4 1941.987575 486.503 Glutamine and serine-rich protein 1 OS=Homo sapiens OX=9606 GN=QSER1 PE=1 SV=3 6.51 2441.5 - 219841 - - - 2.3677 - 1.482 0.356 - 19.5 1 2 0 0.0046 17 0 0 0 3.63E+06 4.10E+06 - - - 2.4599 0.9916 221125_WJC_METTL3_EV_vs_WT_F09.12447.12447.3 0.00314 Jun-64 K.SNGR[166.11]EQDLPLAEAVR[166.11]PK[136.11].T sp|Q96A49|SYAP1_HUMAN 1 1907.0219 0.86 131657 12447 3 1907.02316 636.6812 Synapse-associated protein 1 OS=Homo sapiens OX=9606 GN=SYAP1 PE=1 SV=1 5.9 2442.7 - 58024.3 - - - 0.6534 - 1.46 0.304 - 57.7 1 2 1 0.0012 17 0 0 0 2.35E+06 2.74E+06 - - - 2.885 0.8073 221125_WJC_METTL3_EV_vs_WT_F09.12450.12450.2 4.52 20-May K.LVLVGDGGTGK.T "sp|P62826|RAN_HUMAN,tr|H0YFC6|H0YFC6_HUMAN,tr|B5MDF5|B5MDF5_HUMAN,tr|J3KQE5|J3KQE5_HUMAN,tr|F5H018|F5H018_HUMAN" 5 1014.571 6.77 131660 12450 2 1014.574071 508.2928 GTP-binding nuclear protein Ran OS=Homo sapiens OX=9606 GN=RAN PE=1 SV=3 5.84 2443.1 - 81570.2 - - - 3.0663 - 1.008 0.073 - 53.2 1 2 0 0.0031 11 0 0 0 1.50E+06 2.22E+05 - - - -0.3992 0.9673 221125_WJC_METTL3_EV_vs_WT_F09.12455.12455.2 0.144 Apr-36 K.SENGLEFTSSGSANTETTK.V "sp|P21796|VDAC1_HUMAN,tr|C9JI87|C9JI87_HUMAN" 2 1958.8705 2.31 131663 12455 2 1958.878037 980.4425 Voltage-dependent anion-selective channel protein 1 OS=Homo sapiens OX=9606 GN=VDAC1 PE=1 SV=2 4.25 2443.8 - 27450.3 - - - 3.843 - 0.768 0.39 - 17.4 1 2 0 0.0075 19 0 0 0 4.88E+05 2.11E+05 - - - 1.2702 0.9178 221125_WJC_METTL3_EV_vs_WT_F09.12466.12466.3 0.113 Jun-56 R.QNELR[166.11]QEMLDDVQK[136.11]K[136.11].L "sp|Q15643|TRIPB_HUMAN,tr|H0YJ97|H0YJ97_HUMAN" 2 1898.973 3.76 131671 12466 3 1898.97701 633.9983 Thyroid receptor-interacting protein 11 OS=Homo sapiens OX=9606 GN=TRIP11 PE=1 SV=3 4.78 2445.2 - 131725 - - - 2.0953 - 1.18 0.258 - 45.1 1 2 1 0.004 15 0 0 0 6.20E+06 1.65E+06 - - - 1.8472 1 221125_WJC_METTL3_EV_vs_WT_F09.12474.12474.3 1.43E-08 13/88 K.KQGPVATGVSGDASTNETYLPAR.V "sp|Q9BVV6|TALD3_HUMAN,tr|A0A087WYM5|A0A087WYM5_HUMAN,tr|A0A494C058|A0A494C058_HUMAN,tr|A0A494C0M8|A0A494C0M8_HUMAN,tr|A0A494C075|A0A494C075_HUMAN,tr|A0A494C171|A0A494C171_HUMAN,tr|A0A494C1C3|A0A494C1C3_HUMAN" 7 2318.1503 5.24 131677 12474 3 2318.157547 773.724 Protein TALPID3 OS=Homo sapiens OX=9606 GN=KIAA0586 PE=1 SV=4 6.07 2446.4 - 116121 - - - 3.1465 - 2.917 0.623 - 175.6 1 2 0 0.0073 23 0 0 0 2.62E+06 4.99E+05 - - - 7.9953 0.9981 221125_WJC_METTL3_EV_vs_WT_F09.12480.12480.2 0.00276 16-Jul R.QLDSIVGER.G "sp|P48668|K2C6C_HUMAN,sp|P13647|K2C5_HUMAN,sp|P02538|K2C6A_HUMAN,tr|F8W0C6|F8W0C6_HUMAN" 4 1015.5298 79.86 131682 12480 2 1015.532886 508.7722 "Keratin, type II cytoskeletal 6C OS=Homo sapiens OX=9606 GN=KRT6C PE=1 SV=3" 4.37 2447.1 - 161940 - - - 3.0152 - 1.488 0.411 - 188.1 1 2 0 0.0031 9 0 0 0 2.78E+06 3.48E+04 - - - 3.2255 0.9525 221125_WJC_METTL3_EV_vs_WT_F09.12485.12485.3 4.74E-05 Sep-84 K.HGSYGPAEYDYGHTGYGPSGGS.R sp|Q5D862|FILA2_HUMAN 1 2214.8879 - 131685 12485 3 2214.90035 739.3032 Filaggrin-2 OS=Homo sapiens OX=9606 GN=FLG2 PE=1 SV=1 5.15 2447.8 - 124693 - - - 5.6256 - 2.078 0.619 - 73.6 1 1 0 0.0125 22 0 0 0 - - - - - 7.1718 0.9994 221125_WJC_METTL3_EV_vs_WT_F09.12486.12486.3 0.00872 Jun-88 K.K[136.11]QGPVATGVSGDASTNETYLPAR[166.11].V "sp|Q9BVV6|TALD3_HUMAN,tr|A0A087WYM5|A0A087WYM5_HUMAN,tr|A0A494C058|A0A494C058_HUMAN,tr|A0A494C0M8|A0A494C0M8_HUMAN,tr|A0A494C075|A0A494C075_HUMAN,tr|A0A494C171|A0A494C171_HUMAN,tr|A0A494C1C3|A0A494C1C3_HUMAN" 7 2336.1727 5.24 131686 12486 3 2336.172142 779.7315 Protein TALPID3 OS=Homo sapiens OX=9606 GN=KIAA0586 PE=1 SV=4 6.07 2448 - 72526.5 - - - -0.2487 - 1.578 0.363 - 30.2 1 2 0 -0.0006 23 0 0 0 2.62E+06 4.99E+05 - - - 3.657 0.9976 221125_WJC_METTL3_EV_vs_WT_F09.12490.12490.3 0.002 Sep-48 K.KEKEPEYTLLTER.G "sp|O95793|STAU1_HUMAN,tr|Q5JW30|Q5JW30_HUMAN" 2 1634.8516 2.06 131688 12490 3 1634.854976 545.9578 Double-stranded RNA-binding protein Staufen homolog 1 OS=Homo sapiens OX=9606 GN=STAU1 PE=1 SV=2 4.95 2448.5 - 176994 - - - 2.0944 - 1.807 0.379 - 141.1 1 2 1 0.0034 13 0 0 0 4.31E+06 2.10E+06 - - - 4.3687 1 221125_WJC_METTL3_EV_vs_WT_F09.12492.12492.3 2.10E-11 23/128 L.IC[160.03]NVGAGGPAPAAGAAPAGGPAPSTAAAPAEEK.K sp|P05386|RLA1_HUMAN 1 2855.3872 1.81 131690 12492 3 2855.391483 952.803 60S acidic ribosomal protein P1 OS=Homo sapiens OX=9606 GN=RPLP1 PE=1 SV=1 4.53 2448.8 - 219338 - - - 1.4979 - 3.894 0.655 - 320.6 1 1 0 0.0043 33 0 0 0 4.90E+06 2.70E+06 - - - 8.969 0.9575 221125_WJC_METTL3_EV_vs_WT_F09.12494.12494.3 1.64E-08 16/128 L.IC[160.03]NVGAGGPAPAAGAAPAGGPAPSTAAAPAEEK[136.11].K sp|P05386|RLA1_HUMAN 1 2863.4014 1.81 131692 12494 3 2864.402782 955.4744 60S acidic ribosomal protein P1 OS=Homo sapiens OX=9606 GN=RPLP1 PE=1 SV=1 4.53 2449.1 - 95107.1 - - - 349.7156 - 2.918 0.597 - 132.5 1 1 0 1.0014 33 0 0 0 4.90E+06 2.70E+06 - - - 7.3823 1 221125_WJC_METTL3_EV_vs_WT_F09.12495.12495.4 6.40E-05 10/126 K.SGYHQSASEHGLVVIAPDTSPR[166.11].G "sp|P10768|ESTD_HUMAN,tr|H7BZT7|H7BZT7_HUMAN,tr|U3KQT1|U3KQT1_HUMAN,tr|X6RA14|X6RA14_HUMAN" 4 2317.1326 0.89 131693 12495 4 2317.135278 580.2904 S-formylglutathione hydrolase OS=Homo sapiens OX=9606 GN=ESD PE=1 SV=2 5.94 2449.2 - 71380.7 - - - 1.1372 - 2.343 0.519 - 86.2 1 2 0 0.0026 22 0 0 0 7.44E+05 8.38E+05 - - - 4.0212 1 221125_WJC_METTL3_EV_vs_WT_F09.12497.12497.3 7.71E-06 16/52 K.K[136.11]HPDASVNFSEFSK[136.11].K "sp|P09429|HMGB1_HUMAN,tr|Q5T7C4|Q5T7C4_HUMAN" 2 1607.7915 0.18 131694 12497 3 1607.795375 536.9378 High mobility group protein B1 OS=Homo sapiens OX=9606 GN=HMGB1 PE=1 SV=3 6.75 2449.4 - 1.91E+06 - - - 2.4282 - 2.887 0.553 - 484.5 1 2 0 0.0039 14 0 0 0 1.60E+07 8.72E+07 - - - 7.5219 0.9997 221125_WJC_METTL3_EV_vs_WT_F09.12499.12499.4 4.91E-06 13/96 K.SNGREQDLPLAEAVRPK.T sp|Q96A49|SYAP1_HUMAN 1 1878.9912 1.33 131695 12499 4 1878.99763 470.7551 Synapse-associated protein 1 OS=Homo sapiens OX=9606 GN=SYAP1 PE=1 SV=1 5.9 2449.7 - 227863 - - - 3.4359 - 2.524 0.56 - 155.1 1 2 1 0.0065 17 0 0 0 8.70E+06 6.56E+06 - - - 4.4199 0.9997 221125_WJC_METTL3_EV_vs_WT_F09.12500.12500.4 0.000377 Aug-96 K.SNGR[166.11]EQDLPLAEAVR[166.11]PK[136.11].T sp|Q96A49|SYAP1_HUMAN 1 1907.0219 1.33 131696 12500 4 1907.021137 477.7628 Synapse-associated protein 1 OS=Homo sapiens OX=9606 GN=SYAP1 PE=1 SV=1 5.9 2449.8 - 160732 - - - -0.4074 - 1.431 0.458 - 53.1 1 2 1 -0.0008 17 0 0 0 8.70E+06 6.56E+06 - - - 3.3366 0.9999 221125_WJC_METTL3_EV_vs_WT_F09.12502.12502.4 1.55E-05 11/186 R.ALQR[166.11]PSAAAPQAENGPAAAPAVAAPAATEAPK[136.11].M "sp|Q15020|SART3_HUMAN,tr|A0A499FI31|A0A499FI31_HUMAN" 2 2982.5642 3.75 131698 12502 4 2982.569177 746.6483 Squamous cell carcinoma antigen recognized by T-cells 3 OS=Homo sapiens OX=9606 GN=SART3 PE=1 SV=1 6.19 2450.1 - 185650 - - - 1.6677 - 2.361 0.486 - 39.7 1 2 0 0.005 32 0 0 0 2.08E+07 5.55E+06 - - - 3.7142 1 221125_WJC_METTL3_EV_vs_WT_F09.12513.12513.3 1.63E-07 14/92 K.SLQQPGLPSQSC[160.03]SVQSSGGQPPGR.Q "sp|Q53ET0|CRTC2_HUMAN,tr|Q5T4K5|Q5T4K5_HUMAN,tr|H0YDQ8|H0YDQ8_HUMAN" 3 2438.1608 1.32 131707 12513 3 2438.167776 813.7276 CREB-regulated transcription coactivator 2 OS=Homo sapiens OX=9606 GN=CRTC2 PE=1 SV=2 7.96 2451.6 - 153952 - - - 2.8468 - 2.945 0.681 - 152.6 1 2 0 0.0069 24 0 0 0 4.68E+06 3.55E+06 - - - 8.6392 0.9998 221125_WJC_METTL3_EV_vs_WT_F09.12514.12514.3 0.00166 Sep-56 K.AVDQHNAEAQDIFGK.N "sp|P52732|KIF11_HUMAN,tr|A0A7I2YQY4|A0A7I2YQY4_HUMAN,tr|A0A7I2V3A9|A0A7I2V3A9_HUMAN" 3 1641.7747 10.17 131708 12514 3 1641.778917 548.2655 Kinesin-like protein KIF11 OS=Homo sapiens OX=9606 GN=KIF11 PE=1 SV=2 4.54 2451.7 - 214529 - - - 2.5698 - 2.042 0.469 - 81.7 1 2 0 0.0042 15 0 0 0 5.44E+06 5.35E+05 - - - 5.6306 0.9971 221125_WJC_METTL3_EV_vs_WT_F09.12515.12515.4 0.0111 9/102 R.ETHSVDR[166.11]LPSALTATAC[160.03]K[136.11].S "sp|Q92615|LAR4B_HUMAN,tr|A0A087X183|A0A087X183_HUMAN,tr|H0Y641|H0Y641_HUMAN,tr|H0Y4V9|H0Y4V9_HUMAN" 4 1973.9959 1.31 131709 12515 4 1974.000105 494.5063 La-related protein 4B OS=Homo sapiens OX=9606 GN=LARP4B PE=1 SV=3 6.84 2451.9 - 163067 - - - 2.1074 - 1.88 0.343 - 46.3 1 2 1 0.0042 18 0 0 0 5.60E+07 4.29E+07 - - - 2.4266 0.9745 221125_WJC_METTL3_EV_vs_WT_F09.12516.12516.4 0.00259 9/102 R.ETHSVDRLPSALTATAC[160.03]K.S "sp|Q92615|LAR4B_HUMAN,tr|A0A087X183|A0A087X183_HUMAN,tr|H0Y641|H0Y641_HUMAN,tr|H0Y4V9|H0Y4V9_HUMAN" 4 1955.9735 1.31 131710 12516 4 1955.98274 490.0006 La-related protein 4B OS=Homo sapiens OX=9606 GN=LARP4B PE=1 SV=3 6.84 2452 - 121392 - - - 4.7368 - 1.92 0.326 - 78.2 1 2 1 0.0093 18 0 0 0 5.60E+07 4.29E+07 - - - 2.2844 1 221125_WJC_METTL3_EV_vs_WT_F09.12522.12522.4 1.14E-07 14/78 K.K[136.11]HPDASVNFSEFSK[136.11].K "sp|P09429|HMGB1_HUMAN,tr|Q5T7C4|Q5T7C4_HUMAN" 2 1607.7915 0.22 131715 12522 4 1607.794351 402.9551 High mobility group protein B1 OS=Homo sapiens OX=9606 GN=HMGB1 PE=1 SV=3 6.75 2452.7 - 861224 - - - 1.7913 - 2.812 0.557 - 123.8 1 2 0 0.0029 14 0 0 0 2.56E+06 1.16E+07 - - - 4.4496 0.9948 221125_WJC_METTL3_EV_vs_WT_F09.12523.12523.3 0.00151 Sep-68 K.ANELPQPPVPEPANAGKR.K "sp|P78347|GTF2I_HUMAN,tr|A0A494C1K3|A0A494C1K3_HUMAN" 2 1883.9854 1.85 131716 12523 3 1883.99191 629.0024 General transcription factor II-I OS=Homo sapiens OX=9606 GN=GTF2I PE=1 SV=2 6.19 2452.9 - 225414 - - - 3.4767 - 1.941 0.283 - 59.9 1 2 0 0.0066 18 0 0 0 2.51E+07 1.36E+07 - - - 3.3448 0.9999 221125_WJC_METTL3_EV_vs_WT_F09.12525.12525.3 6.73E-09 15/68 R.ETHSVDR[166.11]LPSALTATAC[160.03]K[136.11].S "sp|Q92615|LAR4B_HUMAN,tr|A0A087X183|A0A087X183_HUMAN,tr|H0Y641|H0Y641_HUMAN,tr|H0Y4V9|H0Y4V9_HUMAN" 4 1973.9959 1.3 131718 12525 3 1973.998703 659.0059 La-related protein 4B OS=Homo sapiens OX=9606 GN=LARP4B PE=1 SV=3 6.84 2453.1 - 231697 - - - 1.3972 - 3.066 0.495 - 246.1 1 2 1 0.0028 18 0 0 0 4.37E+07 3.37E+07 - - - 6.8478 0.9997 221125_WJC_METTL3_EV_vs_WT_F09.12533.12533.3 0.000166 Jul-96 K.AFSTAGSSGSDESHVAAAPPDIC[160.03]SR.T "sp|Q9H3L0|MMAD_HUMAN,tr|F8WEC0|F8WEC0_HUMAN" 2 2476.0925 3.77 131724 12533 3 2476.083457 826.3714 Cobalamin trafficking protein CblD OS=Homo sapiens OX=9606 GN=MMADHC PE=1 SV=2 4.54 2454.1 - 72174 - - - -3.6445 - 1.632 0.571 - 40.7 1 2 0 -0.009 25 0 0 0 1.17E+06 3.11E+05 - - - 6.0304 1 221125_WJC_METTL3_EV_vs_WT_F09.12536.12536.3 9.70E-11 15/80 K.AIEDEGGNPDEIEITSEGNKK.T "sp|Q15424|SAFB1_HUMAN,tr|K7ES42|K7ES42_HUMAN" 2 2244.0394 0.91 131725 12536 3 2244.030823 749.0204 Scaffold attachment factor B1 OS=Homo sapiens OX=9606 GN=SAFB PE=1 SV=4 4 2454.5 - 208638 - - - -3.8065 - 2.938 0.664 - 152.3 1 2 0 -0.0085 21 0 0 0 2.82E+06 3.10E+06 - - - 8.5244 0.9994 221125_WJC_METTL3_EV_vs_WT_F09.12540.12540.3 0.00239 Jul-68 R.DR[166.11]YSSDTTPLLNGSSQDR[166.11].M "sp|O95249|GOSR1_HUMAN,tr|K7EJC8|K7EJC8_HUMAN,tr|G5E9T8|G5E9T8_HUMAN" 3 2030.9408 1.62 131729 12540 3 2030.940642 677.9875 Golgi SNAP receptor complex member 1 OS=Homo sapiens OX=9606 GN=GOSR1 PE=1 SV=1 4.43 2455.1 - 88552.1 - - - -0.0857 - 1.619 0.465 - 35.8 1 2 1 -0.0002 18 0 0 0 4.92E+06 3.03E+06 - - - 4.924 0.9998 221125_WJC_METTL3_EV_vs_WT_F09.12546.12546.3 4.99E-09 21/68 R.ETHSVDRLPSALTATAC[160.03]K.S "sp|Q92615|LAR4B_HUMAN,tr|A0A087X183|A0A087X183_HUMAN,tr|H0Y641|H0Y641_HUMAN,tr|H0Y4V9|H0Y4V9_HUMAN" 4 1955.9735 1.3 131733 12546 3 1955.978186 652.9984 La-related protein 4B OS=Homo sapiens OX=9606 GN=LARP4B PE=1 SV=3 6.84 2455.9 - 725232 - - - 2.4085 - 4.022 0.455 - 526.7 1 2 1 0.0047 18 0 0 0 4.37E+07 3.37E+07 - - - 7.0772 1 221125_WJC_METTL3_EV_vs_WT_F09.12547.12547.4 3.87E-07 14/114 K.GGAAVDPDSGLEHSAHVLEK.G "sp|P09874|PARP1_HUMAN,tr|A0A7I2V3E1|A0A7I2V3E1_HUMAN" 2 1987.9599 1.21 131734 12547 4 1987.964264 497.9973 Poly [ADP-ribose] polymerase 1 OS=Homo sapiens OX=9606 GN=PARP1 PE=1 SV=4 4.72 2456.1 - 190226 - - - 2.1786 - 2.937 0.578 - 149.8 1 2 0 0.0043 20 0 0 0 1.87E+07 1.54E+07 - - - 4.6159 1 221125_WJC_METTL3_EV_vs_WT_F09.12548.12548.3 1.07E-05 Dec-36 K.R[166.11]LHVSNIPFR[166.11].F "sp|O43251|RFOX2_HUMAN,sp|Q9NWB1|RFOX1_HUMAN,sp|A6NFN3|RFOX3_HUMAN,tr|A0A6Q8PGE0|A0A6Q8PGE0_HUMAN,tr|A0A6Q8PH77|A0A6Q8PH77_HUMAN,tr|A0A286YEU2|A0A286YEU2_HUMAN,tr|A0A087X2B1|A0A087X2B1_HUMAN,tr|F8VR27|F8VR27_HUMAN,tr|B7Z1U7|B7Z1U7_HUMAN,tr|B0QYY6|B0QYY6_HUMAN,tr|B0QYV1|B0QYV1_HUMAN,tr|A0A6Q8PHA3|A0A6Q8PHA3_HUMAN,tr|A0A3B3ITL7|A0A3B3ITL7_HUMAN,tr|F8VZY7|F8VZY7_HUMAN,tr|B0QYY4|B0QYY4_HUMAN,tr|J3KNW3|J3KNW3_HUMAN,tr|F8VZG9|F8VZG9_HUMAN,tr|J3QRF4|J3QRF4_HUMAN,tr|F8VRS4|F8VRS4_HUMAN,tr|A0A6Q8PFM4|A0A6Q8PFM4_HUMAN,tr|S4R469|S4R469_HUMAN,tr|A0A804HKG7|A0A804HKG7_HUMAN,tr|A0A0G2JRA5|A0A0G2JRA5_HUMAN,tr|A0A804HJM2|A0A804HJM2_HUMAN,tr|J3QQZ2|J3QQZ2_HUMAN,tr|I3L1D4|I3L1D4_HUMAN,tr|B0QYY7|B0QYY7_HUMAN,tr|A0A0G2JSB3|A0A0G2JSB3_HUMAN" 28 1257.7209 1.1 131735 12548 3 1257.722657 420.2476 RNA binding protein fox-1 homolog 2 OS=Homo sapiens OX=9606 GN=RBFOX2 PE=1 SV=3 12 2456.2 - 167217 - - - 1.3858 - 2.379 0.5 - 307.2 1 2 0 0.0017 10 0 0 0 1.52E+07 1.39E+07 - - - 6.6451 0.9999 221125_WJC_METTL3_EV_vs_WT_F09.12550.12550.3 5.97E-06 Oct-48 R.NREEEWDPEYTPK.S "sp|Q9Y2W1|TR150_HUMAN,tr|A0A3B3ITZ9|A0A3B3ITZ9_HUMAN" 2 1691.7427 2.92 131737 12550 3 1691.743001 564.9215 Thyroid hormone receptor-associated protein 3 OS=Homo sapiens OX=9606 GN=THRAP3 PE=1 SV=2 4.25 2456.5 - 74499 - - - 0.1602 - 2.174 0.602 - 164.2 1 2 1 0.0003 13 0 0 0 3.94E+07 1.35E+07 - - - 7.3571 1 221125_WJC_METTL3_EV_vs_WT_F09.12552.12552.3 1.12E-09 15/52 K.KHPDASVNFSEFSK.K "sp|P09429|HMGB1_HUMAN,tr|Q5T7C4|Q5T7C4_HUMAN" 2 1591.7631 0.18 131738 12552 3 1591.767353 531.595 High mobility group protein B1 OS=Homo sapiens OX=9606 GN=HMGB1 PE=1 SV=3 6.75 2456.7 - 840761 - - - 2.6901 - 2.942 0.617 - 382.1 1 2 0 0.0043 14 0 0 0 1.60E+07 8.70E+07 - - - 8.2855 1 221125_WJC_METTL3_EV_vs_WT_F09.12554.12554.3 4.62E-10 17/76 R.WQPDTEEEYEDSSGNVVNKK.T sp|Q12874|SF3A3_HUMAN 1 2353.0346 4.11 131739 12554 3 2353.035589 785.3521 Splicing factor 3A subunit 3 OS=Homo sapiens OX=9606 GN=SF3A3 PE=1 SV=1 4.08 2456.9 - 438985 - - - 0.4144 - 3.17 0.731 - 313.6 1 2 0 0.001 20 0 0 0 6.90E+07 1.68E+07 - - - 9.4886 0.9998 221125_WJC_METTL3_EV_vs_WT_F09.12555.12555.3 0.00127 Oct-48 R.SIFQHIQSAQSQR.S "sp|Q9Y2W1|TR150_HUMAN,tr|A0A3B3ITZ9|A0A3B3ITZ9_HUMAN" 2 1528.7746 2.53 131740 12555 3 1528.777634 510.5988 Thyroid hormone receptor-associated protein 3 OS=Homo sapiens OX=9606 GN=THRAP3 PE=1 SV=2 9.49 2457.1 - 317042 - - - 1.9591 - 1.801 0.437 - 93.7 1 2 0 0.003 13 0 0 0 5.20E+07 2.06E+07 - - - 5.0065 0.9999 221125_WJC_METTL3_EV_vs_WT_F09.12556.12556.3 5.29E-07 Nov-68 R.DRYSSDTTPLLNGSSQDR.M "sp|O95249|GOSR1_HUMAN,tr|K7EJC8|K7EJC8_HUMAN,tr|G5E9T8|G5E9T8_HUMAN" 3 2010.9243 1.48 131741 12556 3 2010.926778 671.3154 Golgi SNAP receptor complex member 1 OS=Homo sapiens OX=9606 GN=GOSR1 PE=1 SV=1 4.43 2457.2 - 166744 - - - 1.2442 - 2.332 0.608 - 145.1 1 2 1 0.0025 18 0 0 0 4.94E+06 3.33E+06 - - - 7.4263 0.9997 221125_WJC_METTL3_EV_vs_WT_F09.12557.12557.3 0.000209 Sep-56 K.KAEAGAGSATEFQFR.G "sp|Q9NQ39|RS10L_HUMAN,sp|P46783|RS10_HUMAN" 2 1568.7583 1.31 131742 12557 3 1568.76392 523.9267 Putative 40S ribosomal protein S10-like OS=Homo sapiens OX=9606 GN=RPS10P5 PE=5 SV=1 6.14 2457.3 - 118672 - - - 3.5697 - 2.051 0.488 - 134.5 1 2 0 0.0056 15 0 0 0 2.46E+07 1.88E+07 - - - 5.8535 0.9996 221125_WJC_METTL3_EV_vs_WT_F09.12565.12565.3 0.00241 Nov-48 R.SIFQHIQSAQSQR[166.11].S "sp|Q9Y2W1|TR150_HUMAN,tr|A0A3B3ITZ9|A0A3B3ITZ9_HUMAN" 2 1538.7829 2.53 131748 12565 3 1538.786975 513.9349 Thyroid hormone receptor-associated protein 3 OS=Homo sapiens OX=9606 GN=THRAP3 PE=1 SV=2 9.49 2458.4 - 344980 - - - 2.6423 - 1.995 0.402 - 116.3 1 2 0 0.0041 13 0 0 0 5.20E+07 2.06E+07 - - - 4.8933 1 221125_WJC_METTL3_EV_vs_WT_F09.12566.12566.3 9.73E-09 14/76 R.WQPDTEEEYEDSSGNVVNK[136.11]K[136.11].T sp|Q12874|SF3A3_HUMAN 1 2369.063 4.1 131749 12566 3 2369.054814 790.6949 Splicing factor 3A subunit 3 OS=Homo sapiens OX=9606 GN=SF3A3 PE=1 SV=1 4.08 2458.5 - 241266 - - - -3.4613 - 2.779 0.685 - 206.5 1 2 0 -0.0082 20 0 0 0 6.88E+07 1.68E+07 - - - 8.6544 0.9999 221125_WJC_METTL3_EV_vs_WT_F09.12568.12568.3 0.00141 Nov-36 K.RLHVSNIPFR.F "sp|O43251|RFOX2_HUMAN,sp|Q9NWB1|RFOX1_HUMAN,sp|A6NFN3|RFOX3_HUMAN,tr|A0A6Q8PGE0|A0A6Q8PGE0_HUMAN,tr|A0A6Q8PH77|A0A6Q8PH77_HUMAN,tr|A0A286YEU2|A0A286YEU2_HUMAN,tr|A0A087X2B1|A0A087X2B1_HUMAN,tr|F8VR27|F8VR27_HUMAN,tr|B7Z1U7|B7Z1U7_HUMAN,tr|B0QYY6|B0QYY6_HUMAN,tr|B0QYV1|B0QYV1_HUMAN,tr|A0A6Q8PHA3|A0A6Q8PHA3_HUMAN,tr|A0A3B3ITL7|A0A3B3ITL7_HUMAN,tr|F8VZY7|F8VZY7_HUMAN,tr|B0QYY4|B0QYY4_HUMAN,tr|J3KNW3|J3KNW3_HUMAN,tr|F8VZG9|F8VZG9_HUMAN,tr|J3QRF4|J3QRF4_HUMAN,tr|F8VRS4|F8VRS4_HUMAN,tr|A0A6Q8PFM4|A0A6Q8PFM4_HUMAN,tr|S4R469|S4R469_HUMAN,tr|A0A804HKG7|A0A804HKG7_HUMAN,tr|A0A0G2JRA5|A0A0G2JRA5_HUMAN,tr|A0A804HJM2|A0A804HJM2_HUMAN,tr|J3QQZ2|J3QQZ2_HUMAN,tr|I3L1D4|I3L1D4_HUMAN,tr|B0QYY7|B0QYY7_HUMAN,tr|A0A0G2JSB3|A0A0G2JSB3_HUMAN" 28 1237.7044 1.1 131751 12568 3 1237.704619 413.5754 RNA binding protein fox-1 homolog 2 OS=Homo sapiens OX=9606 GN=RBFOX2 PE=1 SV=3 12 2458.8 - 206248 - - - 0.1979 - 1.973 0.389 - 117.2 1 2 0 0.0002 10 0 0 0 1.53E+07 1.39E+07 - - - 4.8615 0.9973 221125_WJC_METTL3_EV_vs_WT_F09.12571.12571.3 0.000153 Aug-72 K.TEELNREVATNSELVQSGK.S "sp|Q04695|K1C17_HUMAN,sp|P02533|K1C14_HUMAN,tr|K7ESE1|K7ESE1_HUMAN,tr|F5GWP8|F5GWP8_HUMAN" 4 2103.0444 22.62 131754 12571 3 2103.04354 702.0221 "Keratin, type I cytoskeletal 17 OS=Homo sapiens OX=9606 GN=KRT17 PE=1 SV=2" 4.49 2459.2 - 99525.2 - - - -0.4047 - 2.091 0.301 - 60.8 1 2 1 -0.0009 19 0 0 0 1.38E+06 6.10E+04 - - - 3.7079 1 221125_WJC_METTL3_EV_vs_WT_F09.12576.12576.3 3.65E-10 16/56 K.K[136.11]AEAGAGSATEFQFR[166.11].G "sp|Q9NQ39|RS10L_HUMAN,sp|P46783|RS10_HUMAN" 2 1586.7808 1.31 131757 12576 3 1586.784013 529.9342 Putative 40S ribosomal protein S10-like OS=Homo sapiens OX=9606 GN=RPS10P5 PE=5 SV=1 6.14 2459.9 - 537117 - - - 2.0312 - 2.751 0.554 - 413.5 1 2 0 0.0032 15 0 0 0 2.46E+07 1.88E+07 - - - 7.3562 1 221125_WJC_METTL3_EV_vs_WT_F09.12577.12577.3 4.45E-08 14/76 K.GGAAVDPDSGLEHSAHVLEK.G "sp|P09874|PARP1_HUMAN,tr|A0A7I2V3E1|A0A7I2V3E1_HUMAN" 2 1987.9599 1.22 131758 12577 3 1987.963143 663.6606 Poly [ADP-ribose] polymerase 1 OS=Homo sapiens OX=9606 GN=PARP1 PE=1 SV=4 4.72 2460 - 231631 - - - 1.6147 - 2.704 0.554 - 218.7 1 2 0 0.0032 20 0 0 0 8.61E+06 7.07E+06 - - - 7.1289 1 221125_WJC_METTL3_EV_vs_WT_F09.12578.12578.3 6.46E-08 20/92 R.REGPGSEPDSQVDGGLSGASLGEK.K "sp|Q5JSZ5|PRC2B_HUMAN,tr|A0A804HKC3|A0A804HKC3_HUMAN,tr|A0A804HJR4|A0A804HJR4_HUMAN" 3 2328.083 1.68 131759 12578 3 2328.082634 777.0349 Protein PRRC2B OS=Homo sapiens OX=9606 GN=PRRC2B PE=1 SV=2 4.18 2460.1 - 360353 - - - -0.1409 - 3.686 0.643 - 359.4 1 2 0 -0.0003 24 0 0 0 1.38E+07 8.23E+06 - - - 8.7387 1 221125_WJC_METTL3_EV_vs_WT_F09.12580.12580.3 2.60E-08 16/76 K.GGAAVDPDSGLEHSAHVLEK[136.11].G "sp|P09874|PARP1_HUMAN,tr|A0A7I2V3E1|A0A7I2V3E1_HUMAN" 2 1995.9741 1.22 131761 12580 3 1995.974356 666.332 Poly [ADP-ribose] polymerase 1 OS=Homo sapiens OX=9606 GN=PARP1 PE=1 SV=4 4.72 2460.4 - 206597 - - - 0.1117 - 3.09 0.631 - 284.7 1 2 0 0.0002 20 0 0 0 8.63E+06 7.07E+06 - - - 8.3119 1 221125_WJC_METTL3_EV_vs_WT_F09.12581.12581.2 8.21E-10 Dec-36 K.TEELNKEVASNSELVQSSR.S "sp|P08779|K1C16_HUMAN,tr|K7ENW6|K7ENW6_HUMAN" 2 2119.0393 999 131762 12581 2 2119.038579 1060.5269 "Keratin, type I cytoskeletal 16 OS=Homo sapiens OX=9606 GN=KRT16 PE=1 SV=4" 4.49 2460.5 - 131418 - - - -0.3431 - 3.02 0.577 - 287.6 1 2 1 -0.0007 19 0 0 0 4.59E+06 0.00E+00 - - - 6.0198 0.9999 221125_WJC_METTL3_EV_vs_WT_F09.12588.12588.2 5.27E-05 13/22 R.AQVQEFC[160.03]DYGTK[136.11].E "sp|Q86U44|MTA70_HUMAN,tr|H0YFV6|H0YFV6_HUMAN" 2 1452.6435 0.02 131767 12588 2 1452.642751 727.329 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 4.37 2461.5 - 2.69E+06 - - - -0.5018 - 2.638 0.543 - 523.3 1 2 0 -0.0007 12 0 0 0 2.48E+06 1.05E+08 - - - 5.6037 0.9845 221125_WJC_METTL3_EV_vs_WT_F09.12589.12589.4 0.0252 Sep-84 K.NSFQPISSLRDDERR.E sp|P98175|RBM10_HUMAN 1 1818.8973 2.56 131768 12589 4 1818.897322 455.7316 RNA-binding protein 10 OS=Homo sapiens OX=9606 GN=RBM10 PE=1 SV=3 6.12 2461.6 - 176687 - - - 0.0269 - 1.797 0.238 - 63.6 1 2 1 0 15 0 0 0 1.35E+07 5.26E+06 - - - 1.5073 1 221125_WJC_METTL3_EV_vs_WT_F09.12592.12592.3 4.80E-07 14/48 R.NR[166.11]EEEWDPEYTPK[136.11].S "sp|Q9Y2W1|TR150_HUMAN,tr|A0A3B3ITZ9|A0A3B3ITZ9_HUMAN" 2 1709.7652 2.92 131771 12592 3 1709.766044 570.929 Thyroid hormone receptor-associated protein 3 OS=Homo sapiens OX=9606 GN=THRAP3 PE=1 SV=2 4.25 2462 - 356058 - - - 0.4936 - 2.596 0.639 - 336.6 1 2 1 0.0008 13 0 0 0 3.94E+07 1.35E+07 - - - 8.2505 0.9646 221125_WJC_METTL3_EV_vs_WT_F09.12606.12606.4 0.0925 Sep-84 K.NSFQPISSLR[166.11]DDER[166.11]R[166.11].E sp|P98175|RBM10_HUMAN 1 1848.9221 2.67 131781 12606 4 1848.920765 463.2378 RNA-binding protein 10 OS=Homo sapiens OX=9606 GN=RBM10 PE=1 SV=3 6.12 2463.9 - 141169 - - - -0.7128 - 1.662 0.206 - 54.2 1 2 1 -0.0013 15 0 0 0 1.34E+07 5.02E+06 - - - 1.2004 0.9999 221125_WJC_METTL3_EV_vs_WT_F09.12611.12611.3 1.36E-05 Oct-60 K.K[136.11]NSSQDDLFPTSDTPR[166.11].A sp|Q9H6T3|RPAP3_HUMAN 1 1824.8609 1.52 131783 12611 3 1824.86512 609.2942 RNA polymerase II-associated protein 3 OS=Homo sapiens OX=9606 GN=RPAP3 PE=1 SV=2 4.43 2464.5 - 188609 - - - 2.3174 - 2.32 0.492 - 107.6 1 2 0 0.0042 16 0 0 0 9.75E+06 6.42E+06 - - - 6.1835 0.9685 221125_WJC_METTL3_EV_vs_WT_F09.12622.12622.3 0.0202 Oct-56 K.NSFQPISSLRDDERR.E sp|P98175|RBM10_HUMAN 1 1818.8973 2.61 131791 12622 3 1818.89858 607.3064 RNA-binding protein 10 OS=Homo sapiens OX=9606 GN=RBM10 PE=1 SV=3 6.12 2466 - 410754 - - - 0.7186 - 1.83 0.171 - 106.4 1 2 1 0.0013 15 0 0 0 8.65E+06 3.31E+06 - - - 2.023 1 221125_WJC_METTL3_EV_vs_WT_F09.12628.12628.3 3.14E-10 Nov-88 R.NPDPGSGPGTLPDPSSK[136.11]PLPGSR[166.11].S sp|Q9NW07|ZN358_HUMAN 1 2247.125 1.78 131795 12628 3 2247.126781 750.049 Zinc finger protein 358 OS=Homo sapiens OX=9606 GN=ZNF358 PE=1 SV=2 5.96 2466.8 - 234728 - - - 0.7725 - 2.549 0.658 - 83.6 1 2 0 0.0017 23 0 0 0 1.08E+07 6.08E+06 - - - 8.0707 0.9983 221125_WJC_METTL3_EV_vs_WT_F09.12630.12630.3 0.0167 Jun-48 R.LLEGEDAHLTQYK.K "sp|Q04695|K1C17_HUMAN,tr|A0A3B3IS58|A0A3B3IS58_HUMAN,tr|F5GWP8|F5GWP8_HUMAN" 3 1515.7569 27.82 131797 12630 3 1515.757475 506.2596 "Keratin, type I cytoskeletal 17 OS=Homo sapiens OX=9606 GN=KRT17 PE=1 SV=2" 4.65 2467 - 123402 - - - 0.3642 - 1.417 0.311 - 46.8 1 2 0 0.0006 13 0 0 0 3.26E+06 1.17E+05 - - - 2.9522 0.9999 221125_WJC_METTL3_EV_vs_WT_F09.12639.12639.3 0.000187 Oct-60 K.KNSSQDDLFPTSDTPR.A sp|Q9H6T3|RPAP3_HUMAN 1 1806.8384 1.53 131802 12639 3 1806.83941 603.2868 RNA polymerase II-associated protein 3 OS=Homo sapiens OX=9606 GN=RPAP3 PE=1 SV=2 4.43 2468.2 - 336588 - - - 0.5474 - 2.131 0.475 - 123.5 1 2 0 0.001 16 0 0 0 9.85E+06 6.42E+06 - - - 5.7768 0.9987 221125_WJC_METTL3_EV_vs_WT_F09.12641.12641.3 0.00218 Jun-44 K.QQHVIETLIGK[136.11]K[136.11].Q "sp|P48643|TCPE_HUMAN,tr|E9PCA1|E9PCA1_HUMAN,tr|B7ZAR1|B7ZAR1_HUMAN,tr|E7ENZ3|E7ENZ3_HUMAN" 4 1408.8373 0.6 131804 12641 3 1408.835443 470.6197 T-complex protein 1 subunit epsilon OS=Homo sapiens OX=9606 GN=CCT5 PE=1 SV=1 8.6 2468.4 - 142611 - - - -1.3174 - 1.312 0.355 - 49.4 1 2 0 -0.0019 12 0 0 0 9.09E+06 1.52E+07 - - - 3.2501 1 221125_WJC_METTL3_EV_vs_WT_F09.12651.12651.3 2.20E-05 24/72 K.TEELNKEVASNSELVQSSR.S "sp|P08779|K1C16_HUMAN,tr|K7ENW6|K7ENW6_HUMAN" 2 2119.0393 3366.91 131810 12651 3 2119.039575 707.3537 "Keratin, type I cytoskeletal 16 OS=Homo sapiens OX=9606 GN=KRT16 PE=1 SV=4" 4.49 2469.8 - 1.08E+06 - - - 0.1269 - 4.157 0.643 - 738.5 1 2 1 0.0003 19 0 0 0 3.56E+08 1.06E+05 - - - 9.2092 0.9998 221125_WJC_METTL3_EV_vs_WT_F09.12667.12667.4 1.82E-05 Dec-96 R.ADTQTYQPYNKDWIKEK.L sp|P84090|ERH_HUMAN 1 2127.0273 1.83 131822 12667 4 2127.028332 532.7641 Enhancer of rudimentary homolog OS=Homo sapiens OX=9606 GN=ERH PE=1 SV=1 6.16 2471.9 - 510059 - - - 0.4927 - 2.066 0.485 - 73.9 1 2 2 0.001 17 0 0 0 5.07E+06 2.77E+06 - - - 3.6991 0.8337 221125_WJC_METTL3_EV_vs_WT_F09.12671.12671.4 0.0238 7/108 K.GEDSVPDTVHHVVVPVNPK[136.11].T "sp|Q92499|DDX1_HUMAN,tr|A0A7I2V2M5|A0A7I2V2M5_HUMAN,tr|A0A087X2G1|A0A087X2G1_HUMAN,tr|A0A7I2V430|A0A7I2V430_HUMAN,tr|A0A7I2V4F0|A0A7I2V4F0_HUMAN,tr|A0A7I2V4J3|A0A7I2V4J3_HUMAN,tr|A0A087WZ71|A0A087WZ71_HUMAN,tr|A0A7I2YQ77|A0A7I2YQ77_HUMAN" 8 2032.0469 1.58 131826 12671 4 2033.053074 509.019 ATP-dependent RNA helicase DDX1 OS=Homo sapiens OX=9606 GN=DDX1 PE=1 SV=2 5.21 2472.4 - 140762 - - - 495.151 - 1.422 0.265 - 17.1 1 2 0 1.0062 19 0 0 0 2.67E+07 1.70E+07 - - - 1.3729 1 221125_WJC_METTL3_EV_vs_WT_F09.12679.12679.4 4.09E-06 12/108 K.GEDSVPDTVHHVVVPVNPK.T "sp|Q92499|DDX1_HUMAN,tr|A0A7I2V2M5|A0A7I2V2M5_HUMAN,tr|A0A087X2G1|A0A087X2G1_HUMAN,tr|A0A7I2V430|A0A7I2V430_HUMAN,tr|A0A7I2V4F0|A0A7I2V4F0_HUMAN,tr|A0A7I2V4J3|A0A7I2V4J3_HUMAN,tr|A0A087WZ71|A0A087WZ71_HUMAN,tr|A0A7I2YQ77|A0A7I2YQ77_HUMAN" 8 2024.0327 1.58 131832 12679 4 2024.035973 507.0155 ATP-dependent RNA helicase DDX1 OS=Homo sapiens OX=9606 GN=DDX1 PE=1 SV=2 5.21 2473.5 - 203313 - - - 1.6151 - 2.373 0.51 - 105.4 1 2 0 0.0033 19 0 0 0 2.67E+07 1.70E+07 - - - 3.9565 1 221125_WJC_METTL3_EV_vs_WT_F09.12683.12683.3 6.10E-07 9/108 R.VTEAPC[160.03]YPGAPSTEASGQTGPQEPTSAR.A sp|P40222|TXLNA_HUMAN 1 2845.2825 1.51 131834 12683 3 2845.283706 949.4348 Alpha-taxilin OS=Homo sapiens OX=9606 GN=TXLNA PE=1 SV=3 4.25 2474.1 - 111708 - - - 0.4358 - 2.21 0.651 - 45.1 1 2 0 0.0012 28 0 0 0 8.72E+06 5.79E+06 - - - 7.622 0.998 221125_WJC_METTL3_EV_vs_WT_F09.12686.12686.4 0.0354 Oct-90 K.IRYESLTDPSKLDSGK.E "sp|Q58FF8|H90B2_HUMAN,sp|P08238|HS90B_HUMAN,sp|Q58FF7|H90B3_HUMAN,sp|P07900|HS90A_HUMAN,tr|G3V2J8|G3V2J8_HUMAN" 5 1807.9316 0.62 131837 12686 4 1807.931601 452.9902 Putative heat shock protein HSP 90-beta 2 OS=Homo sapiens OX=9606 GN=HSP90AB2P PE=1 SV=2 6.12 2474.5 - 99896.6 - - - 0.0044 - 1.652 0.338 - 78.3 1 2 2 0 16 0 0 0 1.50E+06 2.40E+06 - - - 2.3448 0.9991 221125_WJC_METTL3_EV_vs_WT_F09.12693.12693.3 0.000867 Nov-76 R.NPSTVC[160.03]LC[160.03]PEQPTC[160.03]SNADSR[166.11].A "sp|Q9H7E9|CH033_HUMAN,tr|A0A3B3IRR6|A0A3B3IRR6_HUMAN,tr|A0A3B3ITA3|A0A3B3ITA3_HUMAN,tr|A0A3B3IT54|A0A3B3IT54_HUMAN" 4 2301.9652 0.82 131842 12693 3 2301.955343 768.329 UPF0488 protein C8orf33 OS=Homo sapiens OX=9606 GN=C8orf33 PE=1 SV=1 4.37 2475.4 - 124280 - - - -4.2759 - 1.764 0.48 - 110.8 1 2 0 -0.0098 20 0 0 0 4.09E+06 4.96E+06 - - - 5.2658 0.9988 221125_WJC_METTL3_EV_vs_WT_F09.12701.12701.4 0.000956 Oct-96 R.VHTGEKPFPC[160.03]PFPGC[160.03]GK.L "sp|O60481|ZIC3_HUMAN,sp|Q8N9L1|ZIC4_HUMAN,sp|Q96T25|ZIC5_HUMAN,sp|O95409|ZIC2_HUMAN,sp|Q15915|ZIC1_HUMAN,tr|C9JD04|C9JD04_HUMAN" 6 1913.8917 2.37 131848 12701 4 1913.897743 479.4802 Zinc finger protein ZIC 3 OS=Homo sapiens OX=9606 GN=ZIC3 PE=1 SV=1 8.03 2476.4 - 155837 - - - 3.1783 - 1.923 0.357 - 74.8 1 2 0 0.0061 17 0 0 0 1.44E+07 6.08E+06 - - - 2.5587 0.9439 221125_WJC_METTL3_EV_vs_WT_F09.12708.12708.4 0.0319 Jul-96 K.AAVKDVEEEKFPTQLSR.H sp|Q2TAY7|SMU1_HUMAN 1 1946.0109 0.95 131855 12708 4 1946.018676 487.51 WD40 repeat-containing protein SMU1 OS=Homo sapiens OX=9606 GN=SMU1 PE=1 SV=2 4.87 2477.3 - 96134.7 - - - 3.9928 - 1.773 0.263 - 46.7 1 2 2 0.0078 17 0 0 0 1.32E+06 1.39E+06 - - - 1.7118 0.9999 221125_WJC_METTL3_EV_vs_WT_F09.12715.12715.3 9.01E-06 Dec-68 K.ANELPQPPVPEPANAGK[136.11]R[166.11].K "sp|P78347|GTF2I_HUMAN,tr|A0A494C1K3|A0A494C1K3_HUMAN" 2 1902.0078 1.79 131860 12715 3 1902.010954 635.0099 General transcription factor II-I OS=Homo sapiens OX=9606 GN=GTF2I PE=1 SV=2 6.19 2478.2 - 396056 - - - 1.6425 - 2.36 0.512 - 115 1 2 0 0.0031 18 0 0 0 1.12E+08 6.26E+07 - - - 6.3856 0.9997 221125_WJC_METTL3_EV_vs_WT_F09.12718.12718.3 8.08E-07 13/72 K.GEDSVPDTVHHVVVPVNPK.T "sp|Q92499|DDX1_HUMAN,tr|A0A7I2V2M5|A0A7I2V2M5_HUMAN,tr|A0A087X2G1|A0A087X2G1_HUMAN,tr|A0A7I2V430|A0A7I2V430_HUMAN,tr|A0A7I2V4F0|A0A7I2V4F0_HUMAN,tr|A0A7I2V4J3|A0A7I2V4J3_HUMAN,tr|A0A087WZ71|A0A087WZ71_HUMAN,tr|A0A7I2YQ77|A0A7I2YQ77_HUMAN" 8 2024.0327 1.24 131863 12718 3 2024.042232 675.6848 ATP-dependent RNA helicase DDX1 OS=Homo sapiens OX=9606 GN=DDX1 PE=1 SV=2 5.21 2478.6 - 124502 - - - 4.7074 - 2.412 0.575 - 204.7 1 2 0 0.0095 19 0 0 0 8.74E+06 7.08E+06 - - - 7.1111 0.998 221125_WJC_METTL3_EV_vs_WT_F09.12720.12720.3 0.00273 Aug-64 R.TQDHNTPALLPK[136.11]PSLGR[166.11].S sp|Q9BWN1|PRR14_HUMAN 1 1862.0129 1.17 131865 12720 3 1862.018099 621.6782 Proline-rich protein 14 OS=Homo sapiens OX=9606 GN=PRR14 PE=1 SV=1 8.44 2478.9 - 92728.2 - - - 2.7841 - 1.582 0.356 - 63.1 1 2 0 0.0052 17 0 0 0 4.72E+06 4.04E+06 - - - 3.6664 1 221125_WJC_METTL3_EV_vs_WT_F09.12724.12724.4 6.73E-07 19/96 R.TQDHNTPALLPK[136.11]PSLGR[166.11].S sp|Q9BWN1|PRR14_HUMAN 1 1862.0129 1.22 131867 12724 4 1862.015863 466.5105 Proline-rich protein 14 OS=Homo sapiens OX=9606 GN=PRR14 PE=1 SV=1 8.44 2479.4 - 345139 - - - 1.5832 - 3.083 0.538 - 247.5 1 2 0 0.0029 17 0 0 0 1.36E+07 1.12E+07 - - - 4.2988 1 221125_WJC_METTL3_EV_vs_WT_F09.12725.12725.3 1.98E-09 12/108 R.VTEAPC[160.03]YPGAPSTEASGQTGPQEPTSAR[166.11].A sp|P40222|TXLNA_HUMAN 1 2855.2907 1.51 131868 12725 3 2855.291725 952.7709 Alpha-taxilin OS=Homo sapiens OX=9606 GN=TXLNA PE=1 SV=3 4.25 2479.6 - 165102 - - - 0.3464 - 2.586 0.664 - 85.2 1 2 0 0.001 28 0 0 0 8.72E+06 5.79E+06 - - - 8.1285 0.9999 221125_WJC_METTL3_EV_vs_WT_F09.12731.12731.3 4.43E-06 Oct-72 K.GEDSVPDTVHHVVVPVNPK[136.11].T "sp|Q92499|DDX1_HUMAN,tr|A0A7I2V2M5|A0A7I2V2M5_HUMAN,tr|A0A087X2G1|A0A087X2G1_HUMAN,tr|A0A7I2V430|A0A7I2V430_HUMAN,tr|A0A7I2V4F0|A0A7I2V4F0_HUMAN,tr|A0A7I2V4J3|A0A7I2V4J3_HUMAN,tr|A0A087WZ71|A0A087WZ71_HUMAN,tr|A0A7I2YQ77|A0A7I2YQ77_HUMAN" 8 2032.0469 1.24 131872 12731 3 2032.049846 678.3562 ATP-dependent RNA helicase DDX1 OS=Homo sapiens OX=9606 GN=DDX1 PE=1 SV=2 5.21 2480.5 - 123235 - - - 1.4478 - 1.99 0.54 - 105.2 1 2 0 0.0029 19 0 0 0 8.74E+06 7.08E+06 - - - 6.2503 0.9888 221125_WJC_METTL3_EV_vs_WT_F09.12738.12738.3 1.55E-05 Nov-60 Y.RADTQTYQPYNKDWIK.E sp|P84090|ERH_HUMAN 1 2025.9908 0.71 131877 12738 3 2025.991579 676.3376 Enhancer of rudimentary homolog OS=Homo sapiens OX=9606 GN=ERH PE=1 SV=1 8.43 2481.4 - 371434 - - - 0.3653 - 2.57 0.527 - 171.7 1 1 1 0.0007 16 0 0 0 1.17E+07 1.64E+07 - - - 6.8373 0.9975 221125_WJC_METTL3_EV_vs_WT_F09.12741.12741.3 7.18E-05 Oct-84 K.SDILKDPPSEANSIQSANATTK.T sp|Q8N488|RYBP_HUMAN 1 2286.1339 1.23 131879 12741 3 2286.146008 763.0519 RING1 and YY1-binding protein OS=Homo sapiens OX=9606 GN=RYBP PE=1 SV=2 4.56 2481.8 - 169483 - - - 5.281 - 2.539 0.528 - 95.4 1 2 1 0.0121 22 0 0 0 7.36E+06 6.00E+06 - - - 6.6324 0.9998 221125_WJC_METTL3_EV_vs_WT_F09.12742.12742.4 0.00176 Sep-96 R.VHTGEK[136.11]PFPC[160.03]PFPGC[160.03]GK[136.11].L "sp|O60481|ZIC3_HUMAN,sp|Q8N9L1|ZIC4_HUMAN,sp|Q96T25|ZIC5_HUMAN,sp|O95409|ZIC2_HUMAN,sp|Q15915|ZIC1_HUMAN,tr|C9JD04|C9JD04_HUMAN" 6 1929.9201 2.69 131880 12742 4 1929.922118 483.4873 Zinc finger protein ZIC 3 OS=Homo sapiens OX=9606 GN=ZIC3 PE=1 SV=1 8.03 2481.9 - 135385 - - - 1.0664 - 1.587 0.392 - 51 1 2 0 0.0021 17 0 0 0 1.66E+07 6.19E+06 - - - 2.7977 0.9942 221125_WJC_METTL3_EV_vs_WT_F09.12745.12745.2 8.45E-05 Jun-40 K.SPAVATSTAAPPPPSSPLPSK.S "sp|Q14157|UBP2L_HUMAN,tr|F8W726|F8W726_HUMAN" 2 1959.0313 71.46 131883 12745 2 1959.040793 980.5229 Ubiquitin-associated protein 2-like OS=Homo sapiens OX=9606 GN=UBAP2L PE=1 SV=2 8.47 2482.3 - 37373.7 - - - 4.8422 - 1.404 0.486 - 54.3 1 2 0 0.0095 21 0 0 0 1.41E+06 1.97E+04 - - - 3.4619 0.9989 221125_WJC_METTL3_EV_vs_WT_F09.12749.12749.2 6.77E-06 Jul-32 R.AQVQEFC[160.03]DYGTK[136.11]EEC[160.03]MK[136.11].A "sp|Q86U44|MTA70_HUMAN,tr|H0YFV6|H0YFV6_HUMAN" 2 2137.909 0.001 131885 12749 2 2137.910708 1069.9618 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 4.41 2482.8 - 74325.4 - - - 0.8162 - 1.923 0.684 - 79.6 1 2 1 0.0017 17 0 0 0 0.00E+00 1.59E+06 - - - 5.7001 0.9946 221125_WJC_METTL3_EV_vs_WT_F09.12751.12751.2 0.313 16-Jul K.LSDGVAVLK[136.11].V "sp|P10809|CH60_HUMAN,tr|A0A7I2V2X6|A0A7I2V2X6_HUMAN,tr|A0A7I2YQK6|A0A7I2YQK6_HUMAN,tr|A0A7I2V599|A0A7I2V599_HUMAN" 4 908.5422 1.25 131887 12751 2 908.541182 455.2784 "60 kDa heat shock protein, mitochondrial OS=Homo sapiens OX=9606 GN=HSPD1 PE=1 SV=2" 5.84 2483 - 197604 - - - -1.1568 - 1.392 0.166 - 82.2 1 2 0 -0.001 9 0 0 0 8.63E+06 6.89E+06 - - - 1.2236 0.9999 221125_WJC_METTL3_EV_vs_WT_F09.12753.12753.3 0.000237 17/68 K.ANELPQPPVPEPANAGKR.K "sp|P78347|GTF2I_HUMAN,tr|A0A494C1K3|A0A494C1K3_HUMAN" 2 1883.9854 1.79 131888 12753 3 1883.988879 629.0024 General transcription factor II-I OS=Homo sapiens OX=9606 GN=GTF2I PE=1 SV=2 6.19 2483.3 - 913934 - - - 1.8678 - 2.869 0.425 - 236.6 1 2 0 0.0035 18 0 0 0 1.12E+08 6.26E+07 - - - 5.9018 0.9996 221125_WJC_METTL3_EV_vs_WT_F09.12761.12761.3 0.0169 7/108 R.QLASAGTGPC[160.03]PVHPASNGTSPAPALPAR.A sp|Q6ICC9|RTL6_HUMAN 1 2681.3344 4.87 131894 12761 3 2681.335627 894.7854 Retrotransposon Gag-like protein 6 OS=Homo sapiens OX=9606 GN=RTL6 PE=2 SV=1 8.26 2484.3 - 59255.9 - - - 0.4639 - 1.779 0.366 - 29.3 1 2 0 0.0012 28 0 0 0 1.20E+06 2.46E+05 - - - 3.9455 0.9828 221125_WJC_METTL3_EV_vs_WT_F09.12767.12767.4 6.15E-08 13/90 Y.R[166.11]ADTQTYQPYNK[136.11]DWIK[136.11].E sp|P84090|ERH_HUMAN 1 2052.0275 0.47 131897 12767 4 2052.031808 514.0142 Enhancer of rudimentary homolog OS=Homo sapiens OX=9606 GN=ERH PE=1 SV=1 8.43 2485.1 - 212322 - - - 2.095 - 2.648 0.548 - 164.4 1 1 1 0.0043 16 0 0 0 6.15E+06 1.32E+07 - - - 4.3376 0.9999 221125_WJC_METTL3_EV_vs_WT_F09.12768.12768.4 0.000139 8/102 R.DTLLALHQHGHSGPFESK.F sp|Q7Z5L9|I2BP2_HUMAN 1 1972.9755 1.4 131898 12768 4 1972.978578 494.2512 Interferon regulatory factor 2-binding protein 2 OS=Homo sapiens OX=9606 GN=IRF2BP2 PE=1 SV=2 6.26 2485.2 - 121812 - - - 1.5479 - 1.859 0.44 - 24.8 1 2 0 0.0031 18 0 0 0 4.05E+07 2.88E+07 - - - 3.2673 0.9762 221125_WJC_METTL3_EV_vs_WT_F09.12770.12770.3 0.0312 10/124 R.ALQRPSAAAPQAENGPAAAPAVAAPAATEAPK.M "sp|Q15020|SART3_HUMAN,tr|A0A499FI31|A0A499FI31_HUMAN" 2 2964.5417 9.96 131900 12770 3 2965.535136 989.1879 Squamous cell carcinoma antigen recognized by T-cells 3 OS=Homo sapiens OX=9606 GN=SART3 PE=1 SV=1 6.19 2485.5 - 79938.6 - - - 335.095 - 2.033 0.43 - 65.5 1 2 0 0.9934 32 0 0 0 7.86E+05 7.89E+04 - - - 4.6912 0.9866 221125_WJC_METTL3_EV_vs_WT_F09.12777.12777.3 0.0178 Jun-64 K.SSYLPNSDPLHQSDTSK.A "sp|O75179|ANR17_HUMAN,tr|H0YM23|H0YM23_HUMAN" 2 1874.8646 2.44 131903 12777 3 1874.869396 625.9622 Ankyrin repeat domain-containing protein 17 OS=Homo sapiens OX=9606 GN=ANKRD17 PE=1 SV=3 5.19 2486.5 - 148233 - - - 2.5388 - 1.172 0.297 - 20.1 1 2 0 0.0048 17 0 0 0 3.26E+07 1.33E+07 - - - 2.2509 0.9999 221125_WJC_METTL3_EV_vs_WT_F09.12784.12784.4 5.55E-09 19/102 K.K[136.11]GESQTDIEITR[166.11]EEDFTR[166.11].L "sp|P49368|TCPG_HUMAN,tr|B4DUR8|B4DUR8_HUMAN" 2 2181.0544 0.24 131907 12784 4 2181.058365 546.2709 T-complex protein 1 subunit gamma OS=Homo sapiens OX=9606 GN=CCT3 PE=1 SV=4 4.36 2487.3 - 815037 - - - 1.8198 - 3.151 0.57 - 295.3 1 2 1 0.004 18 0 0 0 3.57E+07 1.51E+08 - - - 4.5793 0.9999 221125_WJC_METTL3_EV_vs_WT_F09.12785.12785.3 2.98E-10 17/68 K.K[136.11]GESQTDIEITR[166.11]EEDFTR[166.11].L "sp|P49368|TCPG_HUMAN,tr|B4DUR8|B4DUR8_HUMAN" 2 2181.0544 0.25 131908 12785 3 2181.057428 728.0254 T-complex protein 1 subunit gamma OS=Homo sapiens OX=9606 GN=CCT3 PE=1 SV=4 4.36 2487.5 - 350558 - - - 1.3902 - 2.755 0.618 - 228.6 1 2 1 0.003 18 0 0 0 1.87E+07 7.58E+07 - - - 7.9528 0.9992 221125_WJC_METTL3_EV_vs_WT_F09.12790.12790.4 9.01E-07 16/102 K.KGESQTDIEITREEDFTR.L "sp|P49368|TCPG_HUMAN,tr|B4DUR8|B4DUR8_HUMAN" 2 2153.0237 0.24 131911 12790 4 2153.029158 539.2632 T-complex protein 1 subunit gamma OS=Homo sapiens OX=9606 GN=CCT3 PE=1 SV=4 4.36 2488.2 - 299692 - - - 2.5555 - 2.978 0.423 - 190 1 2 1 0.0055 18 0 0 0 3.57E+07 1.51E+08 - - - 3.2801 0.9982 221125_WJC_METTL3_EV_vs_WT_F09.12792.12792.3 0.0128 Oct-68 K.KGESQTDIEITREEDFTR.L "sp|P49368|TCPG_HUMAN,tr|B4DUR8|B4DUR8_HUMAN" 2 2153.0237 0.25 131913 12792 3 2153.026836 718.6818 T-complex protein 1 subunit gamma OS=Homo sapiens OX=9606 GN=CCT3 PE=1 SV=4 4.36 2488.4 - 155879 - - - 1.477 - 2.002 0.359 - 77.3 1 2 1 0.0032 18 0 0 0 1.87E+07 7.59E+07 - - - 4.2701 0.9997 221125_WJC_METTL3_EV_vs_WT_F09.12793.12793.4 0.00634 10/108 R.ALVDHENVISC[160.03]PHLGASTK.E "sp|O43175|SERA_HUMAN,tr|A0A286YF78|A0A286YF78_HUMAN,tr|A0A2C9F2M7|A0A2C9F2M7_HUMAN,tr|A0A286YF22|A0A286YF22_HUMAN,tr|A0A286YFL2|A0A286YFL2_HUMAN,tr|A0A286YFA2|A0A286YFA2_HUMAN" 6 2047.0157 1.49 131914 12793 4 2047.019227 512.7612 D-3-phosphoglycerate dehydrogenase OS=Homo sapiens OX=9606 GN=PHGDH PE=1 SV=4 5.99 2488.6 - 142324 - - - 1.7357 - 2.19 0.371 - 58.8 1 2 0 0.0036 19 0 0 0 1.35E+07 9.06E+06 - - - 2.7194 0.974 221125_WJC_METTL3_EV_vs_WT_F09.12797.12797.3 0.00203 Aug-48 R.IQFKPDDGISPER.A sp|Q96I24|FUBP3_HUMAN 1 1500.7573 0.33 131916 12797 3 1500.761021 501.2597 Far upstream element-binding protein 3 OS=Homo sapiens OX=9606 GN=FUBP3 PE=1 SV=2 4.56 2489 - 115199 - - - 2.5081 - 1.563 0.186 - 68.9 1 2 0 0.0038 13 0 0 0 1.06E+07 3.24E+07 - - - 1.8236 0.9999 221125_WJC_METTL3_EV_vs_WT_F09.12806.12806.4 0.000554 16/90 R.QATINIGTIGHVAHGK[136.11].S "sp|Q2VIR3|IF2GL_HUMAN,sp|P41091|IF2G_HUMAN,tr|H7BZU1|H7BZU1_HUMAN" 3 1623.8936 0.94 131921 12806 4 1623.89524 406.9807 Eukaryotic translation initiation factor 2 subunit 3B OS=Homo sapiens OX=9606 GN=EIF2S3B PE=2 SV=2 8.76 2490.4 - 249046 - - - 0.9865 - 3.349 0.413 - 317.9 1 2 0 0.0016 16 0 0 0 3.01E+07 3.20E+07 - - - 3.2461 1 221125_WJC_METTL3_EV_vs_WT_F09.12819.12819.3 5.77E-06 16/60 R.QATINIGTIGHVAHGK[136.11].S "sp|Q2VIR3|IF2GL_HUMAN,sp|P41091|IF2G_HUMAN,tr|H7BZU1|H7BZU1_HUMAN" 3 1623.8936 0.89 131928 12819 3 1623.894393 542.3052 Eukaryotic translation initiation factor 2 subunit 3B OS=Homo sapiens OX=9606 GN=EIF2S3B PE=2 SV=2 8.76 2492.2 - 429815 - - - 0.4649 - 3.471 0.494 - 475.1 1 2 0 0.0008 16 0 0 0 2.22E+07 2.50E+07 - - - 7.2405 1 221125_WJC_METTL3_EV_vs_WT_F09.12821.12821.4 1.11E-06 17/90 R.QATINIGTIGHVAHGK.S "sp|Q2VIR3|IF2GL_HUMAN,sp|P41091|IF2G_HUMAN,tr|H7BZU1|H7BZU1_HUMAN" 3 1615.8794 0.94 131929 12821 4 1615.880197 404.9771 Eukaryotic translation initiation factor 2 subunit 3B OS=Homo sapiens OX=9606 GN=EIF2S3B PE=2 SV=2 8.76 2492.5 - 578836 - - - 0.4697 - 3.057 0.487 - 284.8 1 2 0 0.0008 16 0 0 0 3.00E+07 3.20E+07 - - - 3.8583 1 221125_WJC_METTL3_EV_vs_WT_F09.12826.12826.3 1.15E-11 28/88 A.FASSLVSGLNSSASEPAK[136.11]EPAK[136.11]K[136.11].S "sp|Q86U44|MTA70_HUMAN,tr|F5H6D8|F5H6D8_HUMAN,tr|H0YFV6|H0YFV6_HUMAN,tr|B4DTN4|B4DTN4_HUMAN" 4 2328.2387 0.001 131932 12826 3 2328.237107 777.0869 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 8.5 2493.1 - 1.34E+06 - - - -0.7018 - 4.511 0.627 - 939.5 1 1 1 -0.0016 23 0 0 0 0.00E+00 2.02E+08 - - - 9.0642 1 221125_WJC_METTL3_EV_vs_WT_F09.12841.12841.4 7.36E-11 23/132 A.FASSLVSGLNSSASEPAK[136.11]EPAK[136.11]K[136.11].S "sp|Q86U44|MTA70_HUMAN,tr|F5H6D8|F5H6D8_HUMAN,tr|H0YFV6|H0YFV6_HUMAN,tr|B4DTN4|B4DTN4_HUMAN" 4 2328.2387 0 131940 12841 4 2328.237129 583.067 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 8.5 2495.1 - 2.36E+07 - - - -0.6924 - 4.129 0.626 - 347.7 1 1 1 -0.0016 23 0 0 0 3.92E+05 9.47E+08 - - - 5.1337 0.9998 221125_WJC_METTL3_EV_vs_WT_F09.12843.12843.2 4.57E-06 22-Nov R.ALEEANADLEVK.L "sp|P02533|K1C14_HUMAN,sp|P08779|K1C16_HUMAN,sp|P19012|K1C15_HUMAN,sp|P13646|K1C13_HUMAN,tr|K7EMD9|K7EMD9_HUMAN,tr|K7ERE3|K7ERE3_HUMAN" 6 1300.6511 999 131942 12843 2 1300.652377 651.3328 "Keratin, type I cytoskeletal 14 OS=Homo sapiens OX=9606 GN=KRT14 PE=1 SV=4" 4 2495.3 - 132070 - - - 1.0118 - 2.412 0.438 - 355.7 1 2 0 0.0013 12 0 0 0 6.36E+06 0.00E+00 - - - 4.5923 0.8558 221125_WJC_METTL3_EV_vs_WT_F09.12849.12849.2 1.88E-08 26-Dec L.NSSASEPAK[136.11]EPAK[136.11]K[136.11].S "sp|Q86U44|MTA70_HUMAN,tr|F5H6D8|F5H6D8_HUMAN,tr|H0YFV6|H0YFV6_HUMAN,tr|B4DTN4|B4DTN4_HUMAN" 4 1466.7791 0.07 131945 12849 2 1466.775576 734.3968 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 8.5 2496.1 - 136779 - - - -2.4175 - 2.332 0.598 - 449.5 1 1 1 -0.0035 14 0 0 0 3.69E+05 5.55E+06 - - - 5.5815 0.9999 221125_WJC_METTL3_EV_vs_WT_F09.12855.12855.3 6.71E-06 Aug-60 R.EQHLAQLQQLQQMHQK.Q "sp|P49750|YLPM1_HUMAN,tr|F8VU51|F8VU51_HUMAN" 2 1987.0058 15.78 131948 12855 3 1987.008069 663.3425 YLP motif-containing protein 1 OS=Homo sapiens OX=9606 GN=YLPM1 PE=1 SV=4 7.01 2496.9 - 113615 - - - 1.153 - 1.962 0.483 - 95.5 1 2 0 0.0023 16 0 0 0 2.22E+07 1.40E+06 - - - 5.6536 1 221125_WJC_METTL3_EV_vs_WT_F09.12870.12870.3 7.15E-09 18/60 R.QATINIGTIGHVAHGK.S "sp|Q2VIR3|IF2GL_HUMAN,sp|P41091|IF2G_HUMAN,tr|H7BZU1|H7BZU1_HUMAN" 3 1615.8794 0.89 131957 12870 3 1615.876759 539.6338 Eukaryotic translation initiation factor 2 subunit 3B OS=Homo sapiens OX=9606 GN=EIF2S3B PE=2 SV=2 8.76 2498.7 - 560347 - - - -1.6579 - 3.439 0.556 - 508.4 1 2 0 -0.0027 16 0 0 0 2.22E+07 2.49E+07 - - - 7.9074 0.8901 221125_WJC_METTL3_EV_vs_WT_F09.12871.12871.4 281 2/108 Q.C[160.03]FGWDDDEDDDDEEEEDDY.- sp|O95751|LDOC1_HUMAN 1 2411.7292 - 131958 12871 4 2412.726071 603.9396 Protein LDOC1 OS=Homo sapiens OX=9606 GN=LDOC1 PE=1 SV=1 2.94 2498.9 - 500362 - - - 413.3486 - 0.376 0.728 - 2.2 1 1 0 0.9969 19 0 0 0 - - - - - 4.9555 0.8866 221125_WJC_METTL3_EV_vs_WT_F09.12876.12876.3 0.0368 Jun-68 K.YVHYEIDAC[160.03]MDSEAPGSK.D "sp|Q86U44|MTA70_HUMAN,tr|H0YFV6|H0YFV6_HUMAN" 2 2070.8663 -1 131960 12876 3 2070.845625 691.296 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 4.31 2499.6 - 237012 - - - -9.9799 - 1.218 0.379 - 25.6 1 2 0 -0.0207 18 0 0 0 0.00E+00 0.00E+00 - - - 3.2508 0.997 221125_WJC_METTL3_EV_vs_WT_F09.12887.12887.3 0.000138 Aug-72 K.SRDDSQLNGDSSALLNPSK.E "sp|Q9NV96|CC50A_HUMAN,tr|A0A669KB92|A0A669KB92_HUMAN,tr|E5RG19|E5RG19_HUMAN" 3 2002.9556 0.99 131967 12887 3 2002.963352 668.6591 Cell cycle control protein 50A OS=Homo sapiens OX=9606 GN=TMEM30A PE=1 SV=1 4.43 2501.1 - 113275 - - - 3.8823 - 1.931 0.462 - 61.6 1 2 1 0.0078 19 0 0 0 2.70E+06 2.72E+06 - - - 5.3054 0.9999 221125_WJC_METTL3_EV_vs_WT_F09.12889.12889.3 1.32E-07 14/64 K.DHYQDPVPGITPSSSSR[166.11].T sp|Q7KZ85|SPT6H_HUMAN 1 1851.8627 11.1 131969 12889 3 1851.856632 618.2948 Transcription elongation factor SPT6 OS=Homo sapiens OX=9606 GN=SUPT6H PE=1 SV=2 5.21 2501.4 - 134453 - - - -3.2632 - 2.677 0.609 - 261.6 1 2 0 -0.006 17 0 0 0 4.46E+07 4.01E+06 - - - 7.8157 1 221125_WJC_METTL3_EV_vs_WT_F09.12892.12892.3 5.03E-05 Nov-64 K.DHYQDPVPGITPSSSSR.T sp|Q7KZ85|SPT6H_HUMAN 1 1841.8544 11.12 131971 12892 3 1841.850773 614.9587 Transcription elongation factor SPT6 OS=Homo sapiens OX=9606 GN=SUPT6H PE=1 SV=2 5.21 2501.7 - 266520 - - - -1.9719 - 2.516 0.548 - 141.2 1 2 0 -0.0036 17 0 0 0 4.46E+07 4.01E+06 - - - 6.9796 0.9999 221125_WJC_METTL3_EV_vs_WT_F09.12895.12895.3 9.19E-05 Sep-52 K.VQALEEANNDLENK.L sp|P35527|K1C9_HUMAN 1 1585.7584 6.75 131973 12895 3 1585.756838 529.5934 "Keratin, type I cytoskeletal 9 OS=Homo sapiens OX=9606 GN=KRT9 PE=1 SV=3" 4 2502.1 - 144996 - - - -0.9724 - 1.848 0.487 - 125.5 1 2 0 -0.0015 14 0 0 0 3.72E+06 5.51E+05 - - - 5.6011 1 221125_WJC_METTL3_EV_vs_WT_F09.12896.12896.3 8.32E-06 14/72 K.NKPQVPVPGSDISETQVER.K sp|Q96BK5|PINX1_HUMAN 1 2079.0596 1.5 131974 12896 3 2079.062015 694.0272 PIN2\TERF1-interacting telomerase inhibitor 1 OS=Homo sapiens OX=9606 GN=PINX1 PE=1 SV=2 4.68 2502.2 - 164950 - - - 1.139 - 2.504 0.555 - 167.4 1 2 0 0.0024 19 0 0 0 8.94E+06 5.97E+06 - - - 6.9821 1 221125_WJC_METTL3_EV_vs_WT_F09.12908.12908.3 1.61E-07 Dec-92 R.TQSSASLAASYAAQQHPQAAASYR[166.11].G sp|Q96PK6|RBM14_HUMAN 1 2474.1814 1.84 131984 12908 3 2474.183294 825.7344 RNA-binding protein 14 OS=Homo sapiens OX=9606 GN=RBM14 PE=1 SV=2 8.29 2503.8 - 52868.4 - - - 0.772 - 2.661 0.558 - 97.2 1 2 0 0.0019 24 0 0 0 6.94E+08 3.76E+08 - - - 7.0337 1 221125_WJC_METTL3_EV_vs_WT_F09.12911.12911.3 9.12E-08 Dec-92 R.GIASTSDPPTANIKPTPVVSTPSK.V sp|P12270|TPR_HUMAN 1 2364.2537 2.36 131985 12911 3 2364.256774 789.0918 Nucleoprotein TPR OS=Homo sapiens OX=9606 GN=TPR PE=1 SV=3 8.59 2504.2 - 171365 - - - 1.3188 - 2.604 0.63 - 89.9 1 2 0 0.0031 24 0 0 0 3.41E+07 1.45E+07 - - - 7.7859 0.9999 221125_WJC_METTL3_EV_vs_WT_F09.12913.12913.3 0.000157 Jul-96 K.TPEPVVPTAPEPHPTTSTDQPVTPK.L sp|Q14676|MDC1_HUMAN 1 2622.3177 1.93 131986 12913 3 2622.318923 875.1132 Mediator of DNA damage checkpoint protein 1 OS=Homo sapiens OX=9606 GN=MDC1 PE=1 SV=3 4.65 2504.4 - 110401 - - - 0.4614 - 1.829 0.527 - 33.5 1 2 0 0.0012 25 0 0 0 8.56E+06 4.44E+06 - - - 5.8042 1 221125_WJC_METTL3_EV_vs_WT_F09.12917.12917.3 3.33E-15 26/92 R.TQSSASLAASYAAQQHPQAAASYR.G sp|Q96PK6|RBM14_HUMAN 1 2464.1731 1.84 131989 12917 3 2464.17242 822.3983 RNA-binding protein 14 OS=Homo sapiens OX=9606 GN=RBM14 PE=1 SV=2 8.29 2504.9 - 492537 - - - -0.2816 - 5.038 0.609 - 685.8 1 2 0 -0.0007 24 0 0 0 6.94E+08 3.76E+08 - - - 9.0852 1 221125_WJC_METTL3_EV_vs_WT_F09.12918.12918.3 0.000108 Nov-76 K.STTPPPAEPVSLPQEPPKPR.V tr|A0A7I2V647|A0A7I2V647_HUMAN 1 2124.1215 2.42 131990 12918 3 2124.121335 709.0478 Ras GTPase-activating protein-binding protein 2 OS=Homo sapiens OX=9606 GN=G3BP2 PE=1 SV=1 5.86 2505 - 242396 - - - -0.0866 - 2.244 0.523 - 120.2 1 2 0 -0.0002 20 0 0 0 4.37E+07 1.80E+07 - - - 6.3317 0.9997 221125_WJC_METTL3_EV_vs_WT_F09.12919.12919.3 5.86E-06 Oct-52 K.HEK[136.11]EDGAISTIVLR[166.11].G sp|P50990|TCPQ_HUMAN 1 1584.859 0.38 131991 12919 3 1584.858598 529.2936 T-complex protein 1 subunit theta OS=Homo sapiens OX=9606 GN=CCT8 PE=1 SV=4 5.45 2505.1 - 219086 - - - -0.2789 - 2.165 0.447 - 137.9 1 2 1 -0.0004 14 0 0 0 8.60E+06 2.27E+07 - - - 5.5762 0.9999 221125_WJC_METTL3_EV_vs_WT_F09.12923.12923.4 6.67E-05 18/138 R.TQSSASLAASYAAQQHPQAAASYR.G sp|Q96PK6|RBM14_HUMAN 1 2464.1731 1.97 131993 12923 4 2464.175691 617.0506 RNA-binding protein 14 OS=Homo sapiens OX=9606 GN=RBM14 PE=1 SV=2 8.29 2505.7 - 229564 - - - 1.0458 - 2.098 0.444 - 138.5 1 2 0 0.0026 24 0 0 0 1.60E+08 8.10E+07 - - - 3.3277 1 221125_WJC_METTL3_EV_vs_WT_F09.12928.12928.4 1.40E-05 15/138 R.TQSSASLAASYAAQQHPQAAASYR[166.11].G sp|Q96PK6|RBM14_HUMAN 1 2474.1814 1.97 131998 12928 4 2474.181209 619.5526 RNA-binding protein 14 OS=Homo sapiens OX=9606 GN=RBM14 PE=1 SV=2 8.29 2506.3 - 257830 - - - -0.0707 - 2.894 0.51 - 96.6 1 2 0 -0.0002 24 0 0 0 1.60E+08 8.10E+07 - - - 4.0061 0.9994 221125_WJC_METTL3_EV_vs_WT_F09.12930.12930.3 0.00622 Aug-92 R.GIASTSDPPTANIK[136.11]PTPVVSTPSK[136.11].V sp|P12270|TPR_HUMAN 1 2380.2821 2.36 132000 12930 3 2380.277143 794.4346 Nucleoprotein TPR OS=Homo sapiens OX=9606 GN=TPR PE=1 SV=3 8.59 2506.6 - 232892 - - - -2.064 - 1.738 0.387 - 41.6 1 2 0 -0.0049 24 0 0 0 3.41E+07 1.45E+07 - - - 4.1371 1 221125_WJC_METTL3_EV_vs_WT_F09.12931.12931.3 3.62E-07 Dec-92 R.QDHPSSMGVYGQESGGFSGPGENR[166.11].S "sp|Q01844|EWS_HUMAN,tr|B0QYK0|B0QYK0_HUMAN" 2 2489.0541 0.71 132001 12931 3 2489.049106 830.692 RNA-binding protein EWS OS=Homo sapiens OX=9606 GN=EWSR1 PE=1 SV=1 4.65 2506.7 - 173832 - - - -2.0204 - 2.554 0.675 - 184 1 2 0 -0.005 24 0 0 0 2.72E+07 3.82E+07 - - - 8.242 1 221125_WJC_METTL3_EV_vs_WT_F09.12934.12934.3 6.48E-07 23/64 R.EIAGHIMEFSQDQHGSR.F "sp|Q14671|PUM1_HUMAN,tr|Q5T1Z8|Q5T1Z8_HUMAN,tr|H0YDK8|H0YDK8_HUMAN,tr|H0YEH2|H0YEH2_HUMAN,tr|Q5T1Z4|Q5T1Z4_HUMAN,tr|E9PR38|E9PR38_HUMAN" 6 1940.8799 2.14 132002 12934 3 1940.878993 647.9672 Pumilio homolog 1 OS=Homo sapiens OX=9606 GN=PUM1 PE=1 SV=3 5.28 2507.1 - 392217 - - - -0.472 - 4.214 0.682 - 735.3 1 2 0 -0.0009 17 0 0 0 6.07E+07 2.83E+07 - - - 9.7772 0.9998 221125_WJC_METTL3_EV_vs_WT_F09.12935.12935.4 0.000178 Dec-96 R.EIAGHIMEFSQDQHGSR[166.11].F "sp|Q14671|PUM1_HUMAN,tr|Q5T1Z8|Q5T1Z8_HUMAN,tr|H0YDK8|H0YDK8_HUMAN,tr|H0YEH2|H0YEH2_HUMAN,tr|Q5T1Z4|Q5T1Z4_HUMAN,tr|E9PR38|E9PR38_HUMAN" 6 1950.8882 1.76 132003 12935 4 1950.880647 488.7293 Pumilio homolog 1 OS=Homo sapiens OX=9606 GN=PUM1 PE=1 SV=3 5.28 2507.3 - 209596 - - - -3.8608 - 2.262 0.508 - 103.8 1 2 0 -0.0075 17 0 0 0 5.22E+07 2.96E+07 - - - 3.9289 1 221125_WJC_METTL3_EV_vs_WT_F09.12939.12939.4 3.14E-07 22/96 R.EIAGHIMEFSQDQHGSR.F "sp|Q14671|PUM1_HUMAN,tr|Q5T1Z8|Q5T1Z8_HUMAN,tr|H0YDK8|H0YDK8_HUMAN,tr|H0YEH2|H0YEH2_HUMAN,tr|Q5T1Z4|Q5T1Z4_HUMAN,tr|E9PR38|E9PR38_HUMAN" 6 1940.8799 1.75 132005 12939 4 1940.877025 486.2273 Pumilio homolog 1 OS=Homo sapiens OX=9606 GN=PUM1 PE=1 SV=3 5.28 2507.8 - 656538 - - - -1.4859 - 3.754 0.596 - 430.8 1 2 0 -0.0029 17 0 0 0 5.25E+07 2.99E+07 - - - 4.8721 1 221125_WJC_METTL3_EV_vs_WT_F09.12940.12940.3 5.78E-11 20/64 R.EIAGHIMEFSQDQHGSR[166.11].F "sp|Q14671|PUM1_HUMAN,tr|Q5T1Z8|Q5T1Z8_HUMAN,tr|H0YDK8|H0YDK8_HUMAN,tr|H0YEH2|H0YEH2_HUMAN,tr|Q5T1Z4|Q5T1Z4_HUMAN,tr|E9PR38|E9PR38_HUMAN" 6 1950.8882 2.14 132006 12940 3 1950.886958 651.3033 Pumilio homolog 1 OS=Homo sapiens OX=9606 GN=PUM1 PE=1 SV=3 5.28 2507.9 - 383544 - - - -0.6259 - 3.751 0.634 - 512.5 1 2 0 -0.0012 17 0 0 0 6.07E+07 2.83E+07 - - - 8.948 0.9999 221125_WJC_METTL3_EV_vs_WT_F09.12941.12941.3 9.53E-07 Nov-52 K.HEKEDGAISTIVLR.G sp|P50990|TCPQ_HUMAN 1 1566.8366 0.38 132007 12941 3 1566.834588 523.2861 T-complex protein 1 subunit theta OS=Homo sapiens OX=9606 GN=CCT8 PE=1 SV=4 5.45 2508 - 400114 - - - -1.265 - 2.446 0.513 - 170.1 1 2 1 -0.002 14 0 0 0 8.60E+06 2.27E+07 - - - 6.6359 0.9386 221125_WJC_METTL3_EV_vs_WT_F09.12942.12942.3 0.135 Jul-56 K.QSSSSR[166.11]DDNMFQIGK[136.11].M sp|P53999|TCP4_HUMAN 1 1716.7856 0.53 132008 12942 3 1716.785157 573.2691 Activated RNA polymerase II transcriptional coactivator p15 OS=Homo sapiens OX=9606 GN=SUB1 PE=1 SV=3 5.96 2508.1 - 187480 - - - -0.2685 - 1.17 0.238 - 62.8 1 2 1 -0.0005 15 0 0 0 6.10E+06 1.15E+07 - - - 1.603 1 221125_WJC_METTL3_EV_vs_WT_F09.12945.12945.3 5.21E-08 16/68 K.ANELPQPPVPEPANAGK[136.11]R[166.11].K "sp|P78347|GTF2I_HUMAN,tr|A0A494C1K3|A0A494C1K3_HUMAN" 2 1902.0078 1.82 132010 12945 3 1902.005385 635.0099 General transcription factor II-I OS=Homo sapiens OX=9606 GN=GTF2I PE=1 SV=2 6.19 2508.5 - 1.94E+06 - - - -1.2855 - 2.816 0.546 - 178 1 2 0 -0.0024 18 0 0 0 2.95E+08 1.62E+08 - - - 7.2047 0.8102 221125_WJC_METTL3_EV_vs_WT_F09.12953.12953.3 0.0255 May-84 R.RGNVAGDSKNDPPMEAAGFTAQ.V "sp|P68104|EF1A1_HUMAN,sp|Q5VTE0|EF1A3_HUMAN,tr|A0A7I2V659|A0A7I2V659_HUMAN,tr|A0A7I2V3H3|A0A7I2V3H3_HUMAN,tr|A0A7I2V5N4|A0A7I2V5N4_HUMAN,tr|A0A087WVQ9|A0A087WVQ9_HUMAN,tr|A0A087WV01|A0A087WV01_HUMAN" 7 2232.0229 0.31 132015 12953 3 2232.017405 745.0149 Elongation factor 1-alpha 1 OS=Homo sapiens OX=9606 GN=EEF1A1 PE=1 SV=1 4.56 2509.5 - 176612 - - - -2.4816 - 1.684 0.434 - 14.7 1 1 1 -0.0055 22 0 0 0 5.62E+06 1.83E+07 - - - 4.6127 1 221125_WJC_METTL3_EV_vs_WT_F09.12969.12969.3 1.01E-10 15/80 D.HTPSQELALTQSVGGDSSADR[166.11].L "sp|Q86U44|MTA70_HUMAN,tr|H0YFV6|H0YFV6_HUMAN" 2 2165.0224 0 132023 12969 3 2165.014545 722.6814 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 4.54 2511.8 - 177167 - - - -3.6392 - 3.032 0.656 - 215.4 1 1 0 -0.0079 21 0 0 0 5.15E+04 1.33E+07 - - - 8.5109 0.9974 221125_WJC_METTL3_EV_vs_WT_F09.12978.12978.4 0.00309 11/114 K.YDLSGRPLNIKEDPDGENAR.R "sp|Q9P2K5|MYEF2_HUMAN,tr|A0A0A0MR39|A0A0A0MR39_HUMAN,tr|A0A087WUT0|A0A087WUT0_HUMAN,tr|A0A0A0MQW0|A0A0A0MQW0_HUMAN" 4 2258.0927 0.92 132028 12978 4 2258.090406 565.5305 Myelin expression factor 2 OS=Homo sapiens OX=9606 GN=MYEF2 PE=1 SV=3 4.44 2513 - 190339 - - - -1.0327 - 1.973 0.32 - 75.1 1 2 1 -0.0023 20 0 0 0 1.73E+07 1.87E+07 - - - 2.2378 1 221125_WJC_METTL3_EV_vs_WT_F09.12982.12982.3 1.18E-06 14/88 K.SNGSAIQNGSGGSNHLLEC[160.03]GGLR.E "sp|Q9H334|FOXP1_HUMAN,tr|G5E965|G5E965_HUMAN,tr|A0A3B3IRY1|A0A3B3IRY1_HUMAN,tr|A0A087WVT2|A0A087WVT2_HUMAN,tr|A0A3B3IRS5|A0A3B3IRS5_HUMAN,tr|A0A3B3IST0|A0A3B3IST0_HUMAN,tr|A0A3B3ISQ7|A0A3B3ISQ7_HUMAN,tr|C9J0F0|C9J0F0_HUMAN,tr|A0A3B3IU15|A0A3B3IU15_HUMAN,tr|A0A3B3IUB6|A0A3B3IUB6_HUMAN,tr|A0A3B3ITZ4|A0A3B3ITZ4_HUMAN,tr|A0A3B3IU08|A0A3B3IU08_HUMAN,tr|A0A3B3IST6|A0A3B3IST6_HUMAN,tr|A0A3B3ISQ3|A0A3B3ISQ3_HUMAN" 14 2284.0615 13.98 132030 12982 3 2284.063183 762.3611 Forkhead box protein P1 OS=Homo sapiens OX=9606 GN=FOXP1 PE=1 SV=1 6.46 2513.5 - 225253 - - - 0.7565 - 2.857 0.559 - 189.6 1 2 0 0.0017 23 0 0 0 5.53E+06 3.96E+05 - - - 7.2345 1 221125_WJC_METTL3_EV_vs_WT_F09.12984.12984.3 6.33E-07 Sep-72 K.SVQSSNSTTENNNGLGNWR.N "sp|Q9UPQ9|TNR6B_HUMAN,tr|H0Y720|H0Y720_HUMAN" 2 2063.9257 3.96 132031 12984 3 2063.925207 688.9825 Trinucleotide repeat-containing gene 6B protein OS=Homo sapiens OX=9606 GN=TNRC6B PE=1 SV=4 5.72 2513.7 - 179078 - - - -0.2258 - 1.966 0.629 - 90.7 1 2 0 -0.0005 19 0 0 0 3.97E+06 1.00E+06 - - - 7.2134 1 221125_WJC_METTL3_EV_vs_WT_F09.12991.12991.3 8.50E-10 17/76 K.STTPPPAEPVSLPQEPPK[136.11]PR[166.11].V tr|A0A7I2V647|A0A7I2V647_HUMAN 1 2142.144 2.68 132036 12991 3 2142.140357 715.0553 Ras GTPase-activating protein-binding protein 2 OS=Homo sapiens OX=9606 GN=G3BP2 PE=1 SV=1 5.86 2514.6 - 432748 - - - -1.6955 - 2.983 0.613 - 251.1 1 2 0 -0.0036 20 0 0 0 5.22E+07 1.94E+07 - - - 8.0248 0.9977 221125_WJC_METTL3_EV_vs_WT_F09.12998.12998.3 0.0285 Sep-44 R.QSVEADINGLRR.V "sp|P13645|K1C10_HUMAN,sp|Q7Z3Y8|K1C27_HUMAN,sp|P13646|K1C13_HUMAN,tr|A0A1B0GVI3|A0A1B0GVI3_HUMAN,tr|K7EMD9|K7EMD9_HUMAN,tr|K7ERE3|K7ERE3_HUMAN" 6 1356.711 474.37 132041 12998 3 1356.710204 453.2443 "Keratin, type I cytoskeletal 10 OS=Homo sapiens OX=9606 GN=KRT10 PE=1 SV=6" 6.07 2515.5 - 183272 - - - -0.569 - 1.622 0.256 - 125.1 1 2 0 -0.0008 12 0 0 0 1.86E+07 3.93E+04 - - - 2.7346 0.7883 221125_WJC_METTL3_EV_vs_WT_F09.13003.13003.2 0.44 26-Apr R.R[166.11]AEQDSTTVAAFAS.S "sp|Q86U44|MTA70_HUMAN,tr|F5H6D8|F5H6D8_HUMAN,tr|H0YFV6|H0YFV6_HUMAN,tr|B4DTN4|B4DTN4_HUMAN" 4 1462.6928 0.16 132044 13003 2 1462.691844 732.3537 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 4.37 2516.2 - 148981 - - - -0.6235 - 0.85 0.351 - 29 1 1 0 -0.0009 14 0 0 0 7.73E+05 4.97E+06 - - - 1.2254 1 221125_WJC_METTL3_EV_vs_WT_F09.13004.13004.4 1.69E-08 18/102 R.DTLLALHQHGHSGPFESK.F sp|Q7Z5L9|I2BP2_HUMAN 1 1972.9755 1.54 132045 13004 4 1972.973469 494.2512 Interferon regulatory factor 2-binding protein 2 OS=Homo sapiens OX=9606 GN=IRF2BP2 PE=1 SV=2 6.26 2516.3 - 439007 - - - -1.0416 - 3.483 0.557 - 273 1 2 0 -0.0021 18 0 0 0 2.99E+07 1.94E+07 - - - 4.501 0.9967 221125_WJC_METTL3_EV_vs_WT_F09.13009.13009.4 0.012 8/102 R.DTLLALHQHGHSGPFESK[136.11].F sp|Q7Z5L9|I2BP2_HUMAN 1 1980.9897 1.54 132049 13009 4 1980.986401 496.2547 Interferon regulatory factor 2-binding protein 2 OS=Homo sapiens OX=9606 GN=IRF2BP2 PE=1 SV=2 6.26 2516.9 - 354247 - - - -1.6774 - 1.94 0.277 - 40.1 2 2 0 -0.0033 18 0 0 0 2.98E+07 1.94E+07 - - - 1.6337 0.9988 221125_WJC_METTL3_EV_vs_WT_F09.13011.13011.4 0.000442 11/114 K.YDLSGR[166.11]PLNIK[136.11]EDPDGENAR[166.11].R "sp|Q9P2K5|MYEF2_HUMAN,tr|A0A0A0MR39|A0A0A0MR39_HUMAN,tr|A0A087WUT0|A0A087WUT0_HUMAN,tr|A0A0A0MQW0|A0A0A0MQW0_HUMAN" 4 2286.1235 0.92 132050 13011 4 2286.126829 572.5381 Myelin expression factor 2 OS=Homo sapiens OX=9606 GN=MYEF2 PE=1 SV=3 4.44 2517.2 - 575184 - - - 1.4658 - 2.074 0.368 - 64.4 1 2 1 0.0034 20 0 0 0 1.83E+07 1.98E+07 - - - 2.672 0.9049 221125_WJC_METTL3_EV_vs_WT_F09.13020.13020.3 0.401 4/112 R.ATGPEAAGGGGAGGGGGGYRPIIQSPGYK.T sp|Q9ULL5|PRR12_HUMAN 1 2559.2466 2.84 132056 13020 3 2559.254318 854.0895 Proline-rich protein 12 OS=Homo sapiens OX=9606 GN=PRR12 PE=1 SV=3 8.54 2518.3 - 80517.8 - - - 3.0107 - 1.054 0.243 - 10.8 2 2 0 0.0077 29 0 0 0 4.37E+06 1.54E+06 - - - 1.2287 1 221125_WJC_METTL3_EV_vs_WT_F09.13025.13025.3 5.08E-07 15/68 K.ANELPQPPVPEPANAGKR.K "sp|P78347|GTF2I_HUMAN,tr|A0A494C1K3|A0A494C1K3_HUMAN" 2 1883.9854 1.82 132059 13025 3 1883.987626 629.0024 General transcription factor II-I OS=Homo sapiens OX=9606 GN=GTF2I PE=1 SV=2 6.19 2519 - 4.48E+06 - - - 1.2028 - 2.633 0.596 - 161.6 1 2 0 0.0023 18 0 0 0 2.95E+08 1.62E+08 - - - 7.5949 0.8798 221125_WJC_METTL3_EV_vs_WT_F09.13027.13027.3 1.97 Jun-64 R.YFQTTLTPVESEANTSK[136.11].E sp|Q8N9W8|FA71D_HUMAN 1 1922.9353 2.91 132061 13027 3 1922.934452 641.9857 Protein FAM71D OS=Homo sapiens OX=9606 GN=FAM71D PE=2 SV=2 4.53 2519.3 - 287876 - - - -0.4348 - 1.114 0.149 - 43.6 2 2 0 -0.0008 17 0 0 0 3.26E+07 1.12E+07 - - - 0.3344 0.9227 221125_WJC_METTL3_EV_vs_WT_F09.13028.13028.4 0.83 7/102 K.ANELPQPPVPEPANAGKR.K "sp|P78347|GTF2I_HUMAN,tr|A0A494C1K3|A0A494C1K3_HUMAN" 2 1883.9854 2.45 132062 13028 4 1883.989094 472.0036 General transcription factor II-I OS=Homo sapiens OX=9606 GN=GTF2I PE=1 SV=2 6.19 2519.4 - 85818.2 - - - 1.982 - 1.208 0.152 - 29.6 1 2 0 0.0037 18 0 0 0 4.71E+06 1.93E+06 - - - 0.6127 0.895 221125_WJC_METTL3_EV_vs_WT_F09.13035.13035.3 1.24 Jul-52 R.TYSLGSALRPSTSR.S "sp|P08670|VIME_HUMAN,tr|B0YJC4|B0YJC4_HUMAN,tr|A0A1B0GVG8|A0A1B0GVG8_HUMAN,tr|A0A1B0GTT5|A0A1B0GTT5_HUMAN" 4 1494.7791 1.64 132066 13035 3 1494.780163 499.267 Vimentin OS=Homo sapiens OX=9606 GN=VIM PE=1 SV=4 10.83 2520.3 - 116418 - - - 0.7406 - 0.921 0.188 - 55.7 1 2 0 0.0011 14 0 0 0 1.44E+07 8.75E+06 - - - 0.417 0.9691 221125_WJC_METTL3_EV_vs_WT_F09.13040.13040.3 0.000162 Jul-84 K.DHTPSQELALTQSVGGDSSADR[166.11].L "sp|Q86U44|MTA70_HUMAN,tr|H0YFV6|H0YFV6_HUMAN" 2 2280.0494 0.001 132069 13040 3 2280.03151 761.0237 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 4.22 2521 - 147891 - - - -7.8318 - 1.637 0.402 - 27.7 1 2 0 -0.0179 22 0 0 0 0.00E+00 6.61E+06 - - - 4.1855 0.9996 221125_WJC_METTL3_EV_vs_WT_F09.13045.13045.3 2.72E-05 Sep-76 K.SSSATASQPPESLPQPGLQK.S sp|Q5JSZ5|PRC2B_HUMAN 1 2009.0065 1.8 132072 13045 3 2009.010861 670.6761 Protein PRRC2B OS=Homo sapiens OX=9606 GN=PRRC2B PE=1 SV=2 5.72 2521.7 - 125707 - - - 2.1463 - 1.911 0.412 - 59.6 1 2 0 0.0043 20 0 0 0 5.42E+07 3.02E+07 - - - 4.7034 0.9168 221125_WJC_METTL3_EV_vs_WT_F09.13048.13048.3 0.03 Jul-52 R.HQDSWNGLSHEAFR.L "sp|P38646|GRP75_HUMAN,tr|H0Y8K0|H0Y8K0_HUMAN,tr|A0A7I2V2S7|A0A7I2V2S7_HUMAN,tr|A0A7I2V2K6|A0A7I2V2K6_HUMAN,tr|A0A3B3ITI4|A0A3B3ITI4_HUMAN,tr|A0A7I2V3F7|A0A7I2V3F7_HUMAN,tr|A0A7I2YQQ5|A0A7I2YQQ5_HUMAN,tr|D6RCD7|D6RCD7_HUMAN" 8 1682.755 2.91 132075 13048 3 1682.765123 561.9256 "Stress-70 protein, mitochondrial OS=Homo sapiens OX=9606 GN=HSPA9 PE=1 SV=2" 5.99 2522.1 - 62275.8 - - - 6.0359 - 1.297 0.305 - 52.2 1 2 0 0.0102 14 0 0 0 1.05E+06 3.60E+05 - - - 2.6287 0.9128 221125_WJC_METTL3_EV_vs_WT_F09.13054.13054.3 0.0403 Jul-76 K.SSSATASQPPESLPQPGLQK[136.11].S sp|Q5JSZ5|PRC2B_HUMAN 1 2017.0207 0.68 132079 13054 3 2017.028416 673.3475 Protein PRRC2B OS=Homo sapiens OX=9606 GN=PRRC2B PE=1 SV=2 5.72 2523 - 103952 - - - 3.8012 - 1.401 0.203 - 33.4 1 2 0 0.0077 20 0 0 0 2.13E+06 3.15E+06 - - - 1.6191 0.9968 221125_WJC_METTL3_EV_vs_WT_F09.13057.13057.3 0.131 Jul-52 R.TYSLGSALR[166.11]PSTSR[166.11].S "sp|P08670|VIME_HUMAN,tr|B0YJC4|B0YJC4_HUMAN,tr|A0A1B0GVG8|A0A1B0GVG8_HUMAN,tr|A0A1B0GTT5|A0A1B0GTT5_HUMAN" 4 1514.7956 1.64 132080 13057 3 1514.798677 505.9391 Vimentin OS=Homo sapiens OX=9606 GN=VIM PE=1 SV=4 10.83 2523.4 - 266533 - - - 2.0339 - 1.221 0.35 - 52.5 1 2 0 0.0031 14 0 0 0 1.44E+07 8.76E+06 - - - 2.9719 0.9998 221125_WJC_METTL3_EV_vs_WT_F09.13058.13058.4 0.000458 13/96 K.DHPALNYNIVSGPPSHK.T "sp|O15269|SPTC1_HUMAN,tr|A0A2R8Y6A2|A0A2R8Y6A2_HUMAN,tr|A0A2R8Y4S0|A0A2R8Y4S0_HUMAN" 3 1844.9169 1.55 132081 13058 4 1844.919395 462.2365 Serine palmitoyltransferase 1 OS=Homo sapiens OX=9606 GN=SPTLC1 PE=1 SV=1 6.92 2523.5 - 167400 - - - 1.3274 - 1.965 0.379 - 91.2 1 2 0 0.0024 17 0 0 0 7.51E+06 4.85E+06 - - - 2.7587 1 221125_WJC_METTL3_EV_vs_WT_F09.13059.13059.3 1.42E-11 16/60 K.KQISNLQQSISDAEQR.G sp|P04264|K2C1_HUMAN 1 1843.9388 28535.05 132082 13059 3 1843.943891 615.6535 "Keratin, type II cytoskeletal 1 OS=Homo sapiens OX=9606 GN=KRT1 PE=1 SV=6" 6.07 2523.7 - 434138 - - - 2.7588 - 3.509 0.578 - 329.9 1 2 0 0.0051 16 0 0 0 7.15E+08 2.51E+04 - - - 8.2037 0.9993 221125_WJC_METTL3_EV_vs_WT_F09.13061.13061.3 0.00775 6/112 R.ATGPEAAGGGGAGGGGGGYR[166.11]PIIQSPGYK[136.11].T sp|Q9ULL5|PRR12_HUMAN 1 2577.2691 2.84 132084 13061 3 2577.270008 860.097 Proline-rich protein 12 OS=Homo sapiens OX=9606 GN=PRR12 PE=1 SV=3 8.54 2523.9 - 86351 - - - 0.3589 - 1.437 0.381 - 24.6 1 2 0 0.0009 29 0 0 0 4.37E+06 1.54E+06 - - - 3.6216 1 221125_WJC_METTL3_EV_vs_WT_F09.13065.13065.3 6.55E-09 15/76 K.YDLSGRPLNIKEDPDGENAR.R "sp|Q9P2K5|MYEF2_HUMAN,tr|A0A0A0MR39|A0A0A0MR39_HUMAN,tr|A0A087WUT0|A0A087WUT0_HUMAN,tr|A0A0A0MQW0|A0A0A0MQW0_HUMAN" 4 2258.0927 1.65 132086 13065 3 2258.094811 753.7049 Myelin expression factor 2 OS=Homo sapiens OX=9606 GN=MYEF2 PE=1 SV=3 4.44 2524.5 - 174611 - - - 0.918 - 3.062 0.681 - 160.3 1 2 1 0.0021 20 0 0 0 4.57E+06 2.77E+06 - - - 8.8468 0.9999 221125_WJC_METTL3_EV_vs_WT_F09.13066.13066.4 0.000224 9/108 R.GDQLLSVNGVSVEGEHHEK.A "sp|O14910|LIN7A_HUMAN,sp|Q9NUP9|LIN7C_HUMAN,tr|G3V1D4|G3V1D4_HUMAN" 3 2032.9814 1.36 132087 13066 4 2032.984061 509.2526 Protein lin-7 homolog A OS=Homo sapiens OX=9606 GN=LIN7A PE=1 SV=2 4.8 2524.6 - 160682 - - - 1.3104 - 1.471 0.44 - 38 1 2 0 0.0027 19 0 0 0 3.08E+06 2.26E+06 - - - 3.1856 0.9999 221125_WJC_METTL3_EV_vs_WT_F09.13068.13068.3 9.09E-06 Oct-64 K.DHPALNYNIVSGPPSHK[136.11].T "sp|O15269|SPTC1_HUMAN,tr|A0A2R8Y6A2|A0A2R8Y6A2_HUMAN,tr|A0A2R8Y4S0|A0A2R8Y4S0_HUMAN" 3 1852.9311 0.01 132089 13068 3 1852.93486 618.651 Serine palmitoyltransferase 1 OS=Homo sapiens OX=9606 GN=SPTLC1 PE=1 SV=1 6.92 2524.9 - 122981 - - - 2.0044 - 2.215 0.494 - 119.6 1 2 0 0.0037 17 0 0 0 3.15E+04 3.48E+06 - - - 6.0556 0.9994 221125_WJC_METTL3_EV_vs_WT_F09.13073.13073.3 7.08E-05 Jun-84 R.SSVETTPSVIQHVGQPPATPAK.H "sp|Q6W2J9|BCOR_HUMAN,tr|H7BZ37|H7BZ37_HUMAN,tr|H7C2V9|H7C2V9_HUMAN,tr|H7BYY2|H7BYY2_HUMAN,tr|H7C231|H7C231_HUMAN" 5 2230.1594 1.91 132092 13073 3 2230.165234 744.3937 BCL-6 corepressor OS=Homo sapiens OX=9606 GN=BCOR PE=1 SV=1 6.47 2525.7 - 70285.5 - - - 2.6334 - 1.512 0.458 - 25.3 1 2 0 0.0059 22 0 0 0 3.45E+07 1.81E+07 - - - 4.6248 0.7633 221125_WJC_METTL3_EV_vs_WT_F09.13074.13074.3 0.0325 Jul-60 R.REEKEETLVIPSTGIK.L sp|Q96GA3|LTV1_HUMAN 1 1827.9942 0.89 132093 13074 3 1828.002253 610.3387 Protein LTV1 homolog OS=Homo sapiens OX=9606 GN=LTV1 PE=1 SV=1 4.95 2525.9 - 87820.8 - - - 4.4092 - 1.251 0.268 - 29.4 1 2 1 0.0081 16 0 0 0 2.11E+06 2.37E+06 - - - 2.1003 0.9997 221125_WJC_METTL3_EV_vs_WT_F09.13078.13078.3 0.00302 May-72 R.GDQLLSVNGVSVEGEHHEK.A "sp|O14910|LIN7A_HUMAN,sp|Q9NUP9|LIN7C_HUMAN,tr|G3V1D4|G3V1D4_HUMAN" 3 2032.9814 0.53 132097 13078 3 2032.98293 678.6677 Protein lin-7 homolog A OS=Homo sapiens OX=9606 GN=LIN7A PE=1 SV=2 4.8 2526.4 - 75991.8 - - - 0.7541 - 1.568 0.423 - 20.8 1 2 0 0.0015 19 0 0 0 1.11E+06 2.10E+06 - - - 4.3607 1 221125_WJC_METTL3_EV_vs_WT_F09.13084.13084.3 3.50E-10 16/84 R.LLEGEDAHLSSSQFSSGSQSSR.D sp|P02533|K1C14_HUMAN 1 2308.0567 624.8 132101 13084 3 2308.060013 770.3595 "Keratin, type I cytoskeletal 14 OS=Homo sapiens OX=9606 GN=KRT14 PE=1 SV=4" 4.65 2527.2 - 364669 - - - 1.415 - 3.116 0.647 - 191.9 1 2 0 0.0033 22 0 0 0 4.69E+08 7.50E+05 - - - 8.4471 0.9998 221125_WJC_METTL3_EV_vs_WT_F09.13086.13086.4 0.0228 15/96 K.DHPALNYNIVSGPPSHK[136.11].T "sp|O15269|SPTC1_HUMAN,tr|A0A2R8Y6A2|A0A2R8Y6A2_HUMAN,tr|A0A2R8Y4S0|A0A2R8Y4S0_HUMAN" 3 1852.9311 1.55 132103 13086 4 1852.934291 464.2401 Serine palmitoyltransferase 1 OS=Homo sapiens OX=9606 GN=SPTLC1 PE=1 SV=1 6.92 2527.5 - 223645 - - - 1.6973 - 2.562 0.389 - 187.3 1 2 0 0.0031 17 0 0 0 7.48E+06 4.82E+06 - - - 2.9376 0.9999 221125_WJC_METTL3_EV_vs_WT_F09.13090.13090.3 0.000129 Aug-96 K.LGLGLDDESNNQQAAATQSPGDSRR.L "sp|Q09472|EP300_HUMAN,tr|A0A669KB12|A0A669KB12_HUMAN" 2 2599.2222 2.6 132107 13090 3 2599.226521 867.4147 Histone acetyltransferase p300 OS=Homo sapiens OX=9606 GN=EP300 PE=1 SV=2 4.23 2528 - 87251.2 - - - 1.6436 - 2.033 0.546 - 42.5 1 2 0 0.0043 25 0 0 0 1.02E+06 3.92E+05 - - - 6.2585 1 221125_WJC_METTL3_EV_vs_WT_F09.13091.13091.2 1.74E-10 18/30 K.KQISNLQQSISDAEQR.G sp|P04264|K2C1_HUMAN 1 1843.9388 999 132108 13091 2 1843.940432 922.9767 "Keratin, type II cytoskeletal 1 OS=Homo sapiens OX=9606 GN=KRT1 PE=1 SV=6" 6.07 2528.1 - 79193 - - - 0.8829 - 3.899 0.681 - 1140.4 1 2 0 0.0016 16 0 0 0 1.56E+07 0.00E+00 - - - 7.4157 0.9999 221125_WJC_METTL3_EV_vs_WT_F09.13105.13105.3 4.41E-05 10/100 K.NTGVSPASRPSPGTPTSPSNLTSGLK.T sp|Q5VT52|RPRD2_HUMAN 1 2509.2772 1.74 132118 13105 3 2509.275429 837.433 Regulation of nuclear pre-mRNA domain-containing protein 2 OS=Homo sapiens OX=9606 GN=RPRD2 PE=1 SV=1 11 2529.9 - 111715 - - - -0.7237 - 2.044 0.502 - 80.9 1 2 0 -0.0018 26 0 0 0 1.79E+07 1.03E+07 - - - 5.781 0.9989 221125_WJC_METTL3_EV_vs_WT_F09.13112.13112.4 6.65E-05 14/96 R.DSAYQSITHYRPVSASR.S "sp|P50402|EMD_HUMAN,tr|A0A804HIV7|A0A804HIV7_HUMAN,tr|Q5HY57|Q5HY57_HUMAN" 3 1936.9391 1.32 132123 13112 4 1936.943863 485.2421 Emerin OS=Homo sapiens OX=9606 GN=EMD PE=1 SV=1 8.6 2530.9 - 281797 - - - 2.4394 - 2.664 0.321 - 138.2 1 2 0 0.0047 17 0 0 0 2.21E+07 1.67E+07 - - - 2.3589 1 221125_WJC_METTL3_EV_vs_WT_F09.13113.13113.3 8.94E-09 Nov-64 R.DSAYQSITHYRPVSASR.S "sp|P50402|EMD_HUMAN,tr|A0A804HIV7|A0A804HIV7_HUMAN,tr|Q5HY57|Q5HY57_HUMAN" 3 1936.9391 0.95 132124 13113 3 1936.942442 646.6537 Emerin OS=Homo sapiens OX=9606 GN=EMD PE=1 SV=1 8.6 2531 - 216883 - - - 1.7058 - 2.427 0.518 - 160.4 1 2 0 0.0033 17 0 0 0 1.24E+07 1.31E+07 - - - 6.5542 0.9803 221125_WJC_METTL3_EV_vs_WT_F09.13116.13116.2 0.301 Mar-38 K.SSSATASQPPESLPQPGLQK[136.11].S sp|Q5JSZ5|PRC2B_HUMAN 1 2017.0207 2.26 132127 13116 2 2017.018964 1009.5177 Protein PRRC2B OS=Homo sapiens OX=9606 GN=PRRC2B PE=1 SV=2 5.72 2531.4 - 46675.2 - - - -0.885 - 0.741 0.264 - 17.9 1 2 0 -0.0018 20 0 0 0 1.26E+07 5.57E+06 - - - 0.2534 0.9999 221125_WJC_METTL3_EV_vs_WT_F09.13119.13119.4 3.30E-08 25/126 K.NILDRQDPPSVVVTSHQAPGEK.K sp|P25311|ZA2G_HUMAN 1 2386.2241 999 132128 13119 4 2386.227606 597.5633 Zinc-alpha-2-glycoprotein OS=Homo sapiens OX=9606 GN=AZGP1 PE=1 SV=2 5.38 2531.8 - 688937 - - - 1.4747 - 4.442 0.598 - 334.4 1 2 1 0.0035 22 0 0 0 1.43E+07 0.00E+00 - - - 4.9179 0.8741 221125_WJC_METTL3_EV_vs_WT_F09.13122.13122.3 2.75 Jun-84 R.SSVETTPSVIQHVGQPPATPAK[136.11].H "sp|Q6W2J9|BCOR_HUMAN,tr|H7BZ37|H7BZ37_HUMAN,tr|H7C2V9|H7C2V9_HUMAN,tr|H7BYY2|H7BYY2_HUMAN,tr|H7C231|H7C231_HUMAN" 5 2238.1736 1.91 132131 13122 3 2238.172471 747.0651 BCL-6 corepressor OS=Homo sapiens OX=9606 GN=BCOR PE=1 SV=1 6.47 2532.2 - 95922.6 - - - -0.487 - 1.106 0.137 - 26.5 1 2 0 -0.0011 22 0 0 0 3.45E+07 1.81E+07 - - - 0.306 0.9998 221125_WJC_METTL3_EV_vs_WT_F09.13126.13126.4 8.80E-05 9/126 R.LLEGEDAHLSSSQFSSGSQSSR.D sp|P02533|K1C14_HUMAN 1 2308.0567 999 132133 13126 4 2308.062809 578.0215 "Keratin, type I cytoskeletal 14 OS=Homo sapiens OX=9606 GN=KRT14 PE=1 SV=4" 4.65 2532.8 - 319913 - - - 2.6265 - 1.949 0.463 - 49.1 1 2 0 0.0061 22 0 0 0 6.85E+06 0.00E+00 - - - 3.4726 0.999 221125_WJC_METTL3_EV_vs_WT_F09.13131.13131.4 0.000579 Aug-84 K.GVIVDK[136.11]DFSHPQMPK[136.11].K "sp|P48643|TCPE_HUMAN,tr|E9PCA1|E9PCA1_HUMAN,tr|B7ZAR1|B7ZAR1_HUMAN,tr|E7ENZ3|E7ENZ3_HUMAN" 4 1712.8891 0.8 132136 13131 4 1712.889229 429.2295 T-complex protein 1 subunit epsilon OS=Homo sapiens OX=9606 GN=CCT5 PE=1 SV=1 6.75 2533.4 - 138962 - - - 0.0887 - 1.499 0.383 - 23.6 1 2 1 0.0002 15 0 0 0 4.41E+06 5.48E+06 - - - 2.7044 0.9982 221125_WJC_METTL3_EV_vs_WT_F09.13133.13133.3 4.60E-08 13/68 K.C[160.03]ENIQKPLSSVQENIQQK.S "sp|P52732|KIF11_HUMAN,tr|A0A7I2V3A9|A0A7I2V3A9_HUMAN" 2 2142.0739 4.53 132138 13133 3 2142.056995 715.0319 Kinesin-like protein KIF11 OS=Homo sapiens OX=9606 GN=KIF11 PE=1 SV=2 6.14 2533.7 - 203760 - - - -7.8998 - 2.541 0.575 - 224.7 1 2 0 -0.0169 18 0 0 0 3.62E+08 7.99E+07 - - - 7.2682 0.9999 221125_WJC_METTL3_EV_vs_WT_F09.13138.13138.3 1.57E-07 11/100 K.NTGVSPASR[166.11]PSPGTPTSPSNLTSGLK[136.11].T sp|Q5VT52|RPRD2_HUMAN 1 2527.2997 1.73 132140 13138 3 2527.295732 843.4405 Regulation of nuclear pre-mRNA domain-containing protein 2 OS=Homo sapiens OX=9606 GN=RPRD2 PE=1 SV=1 11 2534.4 - 184096 - - - -1.576 - 2.256 0.503 - 83.8 1 2 0 -0.004 26 0 0 0 1.79E+07 1.03E+07 - - - 6.0186 0.9914 221125_WJC_METTL3_EV_vs_WT_F09.13142.13142.3 0.0118 Aug-52 R.NALQQENHIIDGVK.V "sp|Q9GZT3|SLIRP_HUMAN,tr|H0YJW7|H0YJW7_HUMAN,tr|A0A087WUN7|A0A087WUN7_HUMAN,tr|G3V2S9|G3V2S9_HUMAN,tr|H0YJ40|H0YJ40_HUMAN,tr|G3V4X6|G3V4X6_HUMAN" 6 1577.8162 1.51 132143 13142 3 1577.812503 526.946 "SRA stem-loop-interacting RNA-binding protein, mitochondrial OS=Homo sapiens OX=9606 GN=SLIRP PE=1 SV=1" 5.32 2534.9 - 147266 - - - -2.3235 - 1.656 0.227 - 83.9 1 2 0 -0.0037 14 0 0 0 3.04E+06 2.02E+06 - - - 2.4103 1 221125_WJC_METTL3_EV_vs_WT_F09.13145.13145.3 1.97E-06 15/76 K.STTPPPAEPVSLPQEPPKPR.V tr|A0A7I2V647|A0A7I2V647_HUMAN 1 2124.1215 7.9 132144 13145 3 2124.124197 709.0478 Ras GTPase-activating protein-binding protein 2 OS=Homo sapiens OX=9606 GN=G3BP2 PE=1 SV=1 5.86 2535.5 - 291067 - - - 1.2608 - 2.706 0.512 - 220.9 1 2 0 0.0027 20 0 0 0 1.11E+07 1.41E+06 - - - 6.6626 1 221125_WJC_METTL3_EV_vs_WT_F09.13146.13146.2 2.70E-11 Oct-42 R.LLEGEDAHLSSSQFSSGSQSSR.D sp|P02533|K1C14_HUMAN 1 2308.0567 999 132145 13146 2 2308.054683 1155.0356 "Keratin, type I cytoskeletal 14 OS=Homo sapiens OX=9606 GN=KRT14 PE=1 SV=4" 4.65 2535.6 - 181815 - - - -0.8943 - 2.251 0.733 - 120.4 1 2 0 -0.0021 22 0 0 0 2.66E+06 0.00E+00 - - - 6.4491 1 221125_WJC_METTL3_EV_vs_WT_F09.13147.13147.3 4.90E-11 15/68 K.C[160.03]ENIQK[136.11]PLSSVQENIQQK[136.11].S "sp|P52732|KIF11_HUMAN,tr|A0A7I2V3A9|A0A7I2V3A9_HUMAN" 2 2158.1023 4.53 132146 13147 3 2158.099725 720.3747 Kinesin-like protein KIF11 OS=Homo sapiens OX=9606 GN=KIF11 PE=1 SV=2 6.14 2535.7 - 489080 - - - -1.2011 - 3.407 0.654 - 360.9 1 2 0 -0.0026 18 0 0 0 3.62E+08 7.99E+07 - - - 8.8832 0.9999 221125_WJC_METTL3_EV_vs_WT_F09.13148.13148.3 3.13E-06 13/64 R.DSAYQSITHYR[166.11]PVSASR[166.11].S "sp|P50402|EMD_HUMAN,tr|A0A804HIV7|A0A804HIV7_HUMAN,tr|Q5HY57|Q5HY57_HUMAN" 3 1956.9557 0.95 132147 13148 3 1956.964171 653.3258 Emerin OS=Homo sapiens OX=9606 GN=EMD PE=1 SV=1 8.6 2535.9 - 280716 - - - 4.3399 - 2.435 0.62 - 214.2 1 2 0 0.0085 17 0 0 0 1.24E+07 1.31E+07 - - - 7.6983 0.9997 221125_WJC_METTL3_EV_vs_WT_F09.13154.13154.3 0.000258 Oct-48 K.SVEEGKIDGIIDK.T sp|Q96A49|SYAP1_HUMAN 1 1401.7351 5.72 132150 13154 3 1401.736106 468.2523 Synapse-associated protein 1 OS=Homo sapiens OX=9606 GN=SYAP1 PE=1 SV=1 4.32 2536.7 - 297172 - - - 0.6998 - 2 0.458 - 77.4 1 2 1 0.001 13 0 0 0 5.26E+06 9.21E+05 - - - 5.5253 1 221125_WJC_METTL3_EV_vs_WT_F09.13158.13158.3 5.65E-07 Nov-72 R.RQDLPSSLPEPETQAPPRS.- "sp|P49593|PPM1F_HUMAN,tr|B5MCT7|B5MCT7_HUMAN" 2 2104.0549 60.12 132154 13158 3 2104.052168 702.3589 Protein phosphatase 1F OS=Homo sapiens OX=9606 GN=PPM1F PE=1 SV=3 4.68 2537.2 - 129708 - - - -1.2965 - 2.627 0.546 - 149.1 1 2 0 -0.0027 19 0 0 0 7.82E+06 1.30E+05 - - - 6.9995 0.9998 221125_WJC_METTL3_EV_vs_WT_F09.13167.13167.3 0.000361 Jul-76 R.SVSSFPVPQDNVDTHPGSGK.E "sp|Q676U5|A16L1_HUMAN,tr|E7EVC7|E7EVC7_HUMAN,tr|C9JAY7|C9JAY7_HUMAN" 3 2053.9705 18.54 132161 13167 3 2053.968254 685.6641 Autophagy-related protein 16-1 OS=Homo sapiens OX=9606 GN=ATG16L1 PE=1 SV=2 5.19 2538.4 - 83881.6 - - - -1.0925 - 1.638 0.438 - 45.9 1 2 0 -0.0022 20 0 0 0 8.51E+06 4.59E+05 - - - 4.6198 1 221125_WJC_METTL3_EV_vs_WT_F09.13173.13173.4 3.17E-06 11/102 R.HYNEEGSQVYNDAHILEK[136.11].L "sp|Q86U86|PB1_HUMAN,tr|H0Y5B5|H0Y5B5_HUMAN,tr|E7EVG2|E7EVG2_HUMAN" 3 2152.9905 1.33 132165 13173 4 2152.994328 539.2549 Protein polybromo-1 OS=Homo sapiens OX=9606 GN=PBRM1 PE=1 SV=1 4.8 2539.2 - 183040 - - - 1.7724 - 2.106 0.576 - 58.2 1 2 0 0.0038 18 0 0 0 6.43E+06 4.82E+06 - - - 4.4936 1 221125_WJC_METTL3_EV_vs_WT_F09.13185.13185.3 1.19E-05 15/64 K.MAPVPLDDSNRPASLTK.D "sp|Q9NYF8|BCLF1_HUMAN,tr|E9PKI6|E9PKI6_HUMAN,tr|A0A1W2PQ43|A0A1W2PQ43_HUMAN,tr|E9PK91|E9PK91_HUMAN,tr|E9PJA7|E9PJA7_HUMAN,tr|E9PK09|E9PK09_HUMAN,tr|E9PQN2|E9PQN2_HUMAN" 7 1810.9247 2.71 132170 13185 3 1810.928351 604.6489 Bcl-2-associated transcription factor 1 OS=Homo sapiens OX=9606 GN=BCLAF1 PE=1 SV=2 5.71 2541.2 - 497675 - - - 1.9973 - 2.518 0.534 - 170.9 1 2 0 0.0036 17 0 0 0 1.67E+07 6.15E+06 - - - 6.8255 0.8845 221125_WJC_METTL3_EV_vs_WT_F09.13189.13189.3 1.21 Aug-44 R.VC[160.03]EEIAIIPSK[136.11]K[136.11].L "sp|P08708|RS17_HUMAN,tr|H0YN73|H0YN73_HUMAN,tr|H3BNC9|H3BNC9_HUMAN,tr|H0YN88|H0YN88_HUMAN,tr|A0A075B716|A0A075B716_HUMAN" 5 1401.7872 1.43 132172 13189 3 1401.790713 468.2697 40S ribosomal protein S17 OS=Homo sapiens OX=9606 GN=RPS17 PE=1 SV=2 6.11 2541.8 - 100663 - - - 2.479 - 1.474 0.115 - 72.3 1 2 0 0.0035 12 0 0 0 4.78E+06 3.33E+06 - - - 0.8966 1 221125_WJC_METTL3_EV_vs_WT_F09.13198.13198.3 4.13E-07 Dec-64 Y.VHYEIDAC[160.03]MDSEAPGSK[136.11].D "sp|Q86U44|MTA70_HUMAN,tr|H0YFV6|H0YFV6_HUMAN" 2 1915.8172 0.01 132177 13198 3 1916.819474 639.613 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 4.31 2543.1 - 155918 - - - 523.1762 - 2.873 0.679 - 158.6 1 1 0 1.0023 17 0 0 0 3.31E+04 3.65E+06 - - - 8.4987 0.9991 221125_WJC_METTL3_EV_vs_WT_F09.13200.13200.4 1.02E-05 11/114 K.YDLSGRPLNIKEDPDGENAR.R "sp|Q9P2K5|MYEF2_HUMAN,tr|A0A0A0MR39|A0A0A0MR39_HUMAN,tr|A0A087WUT0|A0A087WUT0_HUMAN,tr|A0A0A0MQW0|A0A0A0MQW0_HUMAN" 4 2258.0927 0.92 132178 13200 4 2258.099869 565.5305 Myelin expression factor 2 OS=Homo sapiens OX=9606 GN=MYEF2 PE=1 SV=3 4.44 2543.3 - 355136 - - - 3.158 - 2.279 0.456 - 64.8 1 2 1 0.0071 20 0 0 0 5.07E+07 5.50E+07 - - - 3.4684 0.9998 221125_WJC_METTL3_EV_vs_WT_F09.13201.13201.4 6.53E-05 13/102 R.HYNEEGSQVYNDAHILEK.L "sp|Q86U86|PB1_HUMAN,tr|H0Y5B5|H0Y5B5_HUMAN,tr|E7EVG2|E7EVG2_HUMAN" 3 2144.9763 1.33 132179 13201 4 2144.984275 537.2514 Protein polybromo-1 OS=Homo sapiens OX=9606 GN=PBRM1 PE=1 SV=1 4.8 2543.4 - 125816 - - - 3.7124 - 2.037 0.525 - 82.7 1 2 0 0.008 18 0 0 0 6.41E+06 4.82E+06 - - - 4.0371 0.9994 221125_WJC_METTL3_EV_vs_WT_F09.13214.13214.4 0.00665 Nov-78 R.QRPSEIKDYSPYFK.T sp|P08779|K1C16_HUMAN 1 1756.8784 207.95 132188 13214 4 1756.881987 440.2269 "Keratin, type I cytoskeletal 16 OS=Homo sapiens OX=9606 GN=KRT16 PE=1 SV=4" 8.43 2545.2 - 335969 - - - 2.0218 - 1.852 0.431 - 107.3 1 2 1 0.0036 14 0 0 0 3.21E+07 1.54E+05 - - - 3.2007 0.9996 221125_WJC_METTL3_EV_vs_WT_F09.13215.13215.3 4.94E-08 14/52 R.QRPSEIKDYSPYFK.T sp|P08779|K1C16_HUMAN 1 1756.8784 635.75 132189 13215 3 1756.884259 586.6334 "Keratin, type I cytoskeletal 16 OS=Homo sapiens OX=9606 GN=KRT16 PE=1 SV=4" 8.43 2545.4 - 181698 - - - 3.315 - 2.64 0.553 - 278.2 1 2 1 0.0058 14 0 0 0 2.16E+07 3.40E+04 - - - 7.2837 0.895 221125_WJC_METTL3_EV_vs_WT_F09.13218.13218.2 1.79 Mar-34 K.C[160.03]ENIQKPLSSVQENIQQK.S "sp|P52732|KIF11_HUMAN,tr|A0A7I2V3A9|A0A7I2V3A9_HUMAN" 2 2142.0739 39.78 132190 13218 2 2142.070355 1072.0442 Kinesin-like protein KIF11 OS=Homo sapiens OX=9606 GN=KIF11 PE=1 SV=2 6.14 2545.9 - 40341.5 - - - -1.6629 - 0.759 0.141 - 17.9 1 2 0 -0.0036 18 0 0 0 2.01E+06 5.06E+04 - - - -0.5966 0.9999 221125_WJC_METTL3_EV_vs_WT_F09.13252.13252.4 1.42E-05 Sep-96 R.DSAYQSITHYR[166.11]PVSASR[166.11].S "sp|P50402|EMD_HUMAN,tr|A0A804HIV7|A0A804HIV7_HUMAN,tr|Q5HY57|Q5HY57_HUMAN" 3 1956.9557 1.33 132208 13252 4 1956.96037 490.2462 Emerin OS=Homo sapiens OX=9606 GN=EMD PE=1 SV=1 8.6 2550.6 - 47609.6 - - - 2.3976 - 1.76 0.532 - 60 1 2 0 0.0047 17 0 0 0 2.21E+07 1.67E+07 - - - 4.0515 0.9933 221125_WJC_METTL3_EV_vs_WT_F09.13257.13257.3 0.00431 Jul-76 R.ESTQLSPADLTEGK[136.11]PTDPSK[136.11].L sp|Q08J23|NSUN2_HUMAN 1 2116.0507 0.24 132211 13257 3 2116.059394 706.3575 RNA cytosine C(5)-methyltransferase NSUN2 OS=Homo sapiens OX=9606 GN=NSUN2 PE=1 SV=2 4.32 2551.4 - 103044 - - - 4.128 - 1.607 0.342 - 41 1 2 0 0.0087 20 0 0 0 1.56E+06 6.48E+06 - - - 3.5014 0.9998 221125_WJC_METTL3_EV_vs_WT_F09.13259.13259.3 2.05E-06 Aug-56 K.SK[136.11]NDC[160.03]DEEFQYC[160.03]LSK[136.11].L "sp|Q9BZM1|PG12A_HUMAN,tr|A0A0C4DGC6|A0A0C4DGC6_HUMAN,tr|A0A2R8Y3M9|A0A2R8Y3M9_HUMAN" 3 1937.8106 1.69 132213 13259 3 1937.81549 646.9442 Group XIIA secretory phospholipase A2 OS=Homo sapiens OX=9606 GN=PLA2G12A PE=1 SV=1 4.32 2551.6 - 104912 - - - 2.5085 - 1.919 0.624 - 96.9 1 2 1 0.0049 15 0 0 0 1.01E+07 5.98E+06 - - - 7.1964 0.9997 221125_WJC_METTL3_EV_vs_WT_F09.13260.13260.3 0.000312 Sep-76 R.ESTQLSPADLTEGKPTDPSK.L sp|Q08J23|NSUN2_HUMAN 1 2100.0223 0.84 132214 13260 3 2100.029089 701.0147 RNA cytosine C(5)-methyltransferase NSUN2 OS=Homo sapiens OX=9606 GN=NSUN2 PE=1 SV=2 4.32 2551.8 - 87821.8 - - - 3.2523 - 2.16 0.462 - 82.2 1 2 0 0.0068 20 0 0 0 1.21E+07 1.44E+07 - - - 5.5573 1 221125_WJC_METTL3_EV_vs_WT_F09.13266.13266.3 1.37E-10 19/76 K.SSSATASQPPESLPQPGLQK.S sp|Q5JSZ5|PRC2B_HUMAN 1 2009.0065 1.8 132219 13266 3 2009.011831 670.6761 Protein PRRC2B OS=Homo sapiens OX=9606 GN=PRRC2B PE=1 SV=2 5.72 2552.5 - 346300 - - - 2.6292 - 2.967 0.625 - 278.3 1 2 0 0.0053 20 0 0 0 5.42E+07 3.00E+07 - - - 8.1451 0.975 221125_WJC_METTL3_EV_vs_WT_F09.13268.13268.4 0.00022 11/108 T.EC[160.03]C[160.03]HGDLLEC[160.03]ADDRADLAK.Y "sp|P02768|ALBU_HUMAN,tr|B7WNR0|B7WNR0_HUMAN,tr|H0YA55|H0YA55_HUMAN,tr|A0A0C4DGB6|A0A0C4DGB6_HUMAN,tr|D6RHD5|D6RHD5_HUMAN,tr|C9JKR2|C9JKR2_HUMAN" 6 2246.9355 0.9 132221 13268 4 2246.939951 562.7411 Albumin OS=Homo sapiens OX=9606 GN=ALB PE=1 SV=2 4.23 2552.8 - 233179 - - - 2.0023 - 1.861 0.517 - 56.6 1 1 1 0.0045 19 0 0 0 1.27E+07 1.41E+07 - - - 3.9348 0.9996 221125_WJC_METTL3_EV_vs_WT_F09.13273.13273.3 0.000368 Oct-76 K.SSSATASQPPESLPQPGLQK[136.11].S sp|Q5JSZ5|PRC2B_HUMAN 1 2017.0207 1.92 132225 13273 3 2017.024149 673.3475 Protein PRRC2B OS=Homo sapiens OX=9606 GN=PRRC2B PE=1 SV=2 5.72 2553.4 - 149758 - - - 1.6857 - 2.104 0.361 - 73.4 1 2 0 0.0034 20 0 0 0 4.72E+07 2.45E+07 - - - 4.3684 1 221125_WJC_METTL3_EV_vs_WT_F09.13275.13275.3 1.48E-10 13/56 K.SKNDC[160.03]DEEFQYC[160.03]LSK.L "sp|Q9BZM1|PG12A_HUMAN,tr|A0A0C4DGC6|A0A0C4DGC6_HUMAN,tr|A0A2R8Y3M9|A0A2R8Y3M9_HUMAN" 3 1921.7822 1.69 132226 13275 3 1921.785737 641.6014 Group XIIA secretory phospholipase A2 OS=Homo sapiens OX=9606 GN=PLA2G12A PE=1 SV=1 4.32 2553.7 - 369586 - - - 1.8254 - 2.745 0.739 - 253.1 1 2 1 0.0035 15 0 0 0 1.01E+07 5.98E+06 - - - 9.413 0.8948 221125_WJC_METTL3_EV_vs_WT_F09.13277.13277.4 0.112 16/138 T.SGGPK[136.11]PSTASAVPELATDPELEK[136.11]K[136.11].L "sp|Q86U44|MTA70_HUMAN,tr|B4E349|B4E349_HUMAN,tr|F5H6D8|F5H6D8_HUMAN,tr|H0YFV6|H0YFV6_HUMAN,tr|B4DTN4|B4DTN4_HUMAN" 5 2432.2861 0.001 132228 13277 4 2432.294948 609.0788 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 4.87 2553.9 - 316671 - - - 3.6439 - 2.428 0.38 - 119.1 1 1 0 0.0089 24 0 0 0 0.00E+00 4.86E+06 - - - 2.8158 0.9979 221125_WJC_METTL3_EV_vs_WT_F09.13283.13283.2 0.0319 16-Jul K.SPLQSVVVR.R "sp|Q9Y2W1|TR150_HUMAN,tr|A0A3B3ITZ9|A0A3B3ITZ9_HUMAN" 2 983.5764 2.59 132232 13283 2 983.57875 492.7955 Thyroid hormone receptor-associated protein 3 OS=Homo sapiens OX=9606 GN=THRAP3 PE=1 SV=2 9.47 2554.8 - 165325 - - - 2.4096 - 1.486 0.344 - 194.2 1 2 0 0.0024 9 0 0 0 7.57E+06 2.92E+06 - - - 2.7269 1 221125_WJC_METTL3_EV_vs_WT_F09.13293.13293.3 5.81E-09 15/84 R.SSVETTPSVIQHVGQPPATPAK.H "sp|Q6W2J9|BCOR_HUMAN,tr|H7BZ37|H7BZ37_HUMAN,tr|H7C2V9|H7C2V9_HUMAN,tr|H7BYY2|H7BYY2_HUMAN,tr|H7C231|H7C231_HUMAN" 5 2230.1594 1.91 132240 13293 3 2230.165784 744.3937 BCL-6 corepressor OS=Homo sapiens OX=9606 GN=BCOR PE=1 SV=1 6.47 2556.2 - 206918 - - - 2.8801 - 2.914 0.586 - 167.6 1 2 0 0.0064 22 0 0 0 3.45E+07 1.81E+07 - - - 7.6072 0.9854 221125_WJC_METTL3_EV_vs_WT_F09.13297.13297.3 2.81E-06 Sep-72 T.EC[160.03]C[160.03]HGDLLEC[160.03]ADDRADLAK.Y "sp|P02768|ALBU_HUMAN,tr|B7WNR0|B7WNR0_HUMAN,tr|H0YA55|H0YA55_HUMAN,tr|A0A0C4DGB6|A0A0C4DGB6_HUMAN,tr|D6RHD5|D6RHD5_HUMAN,tr|C9JKR2|C9JKR2_HUMAN" 6 2246.9355 999 132244 13297 3 2246.940762 749.9858 Albumin OS=Homo sapiens OX=9606 GN=ALB PE=1 SV=2 4.23 2556.7 - 97765.3 - - - 2.3632 - 1.861 0.698 - 79 1 1 1 0.0053 19 0 0 0 2.92E+06 0.00E+00 - - - 7.8465 0.9978 221125_WJC_METTL3_EV_vs_WT_F09.13303.13303.3 0.00819 Jul-56 K.TK[136.11]PYIQVDIGGGQTK[136.11].T "sp|P11021|BIP_HUMAN,tr|A0A7P0TB36|A0A7P0TB36_HUMAN,tr|A0A7P0TAI0|A0A7P0TAI0_HUMAN" 3 1619.8854 0.58 132248 13303 3 1619.890444 540.9691 Endoplasmic reticulum chaperone BiP OS=Homo sapiens OX=9606 GN=HSPA5 PE=1 SV=2 8.17 2557.5 - 131448 - - - 3.1311 - 1.532 0.371 - 57.1 1 2 0 0.0051 15 0 0 0 1.47E+06 2.53E+06 - - - 3.788 0.9993 221125_WJC_METTL3_EV_vs_WT_F09.13304.13304.2 6.32E-06 Sep-32 R.AIGGGLSSVGGGSSTIK.Y "sp|P48668|K2C6C_HUMAN,sp|P02538|K2C6A_HUMAN" 2 1446.7678 23.99 132249 13304 2 1446.772112 724.3912 "Keratin, type II cytoskeletal 6C OS=Homo sapiens OX=9606 GN=KRT6C PE=1 SV=3" 8.8 2557.7 - 125284 - - - 2.9652 - 1.977 0.509 - 174.4 1 2 0 0.0043 17 0 0 0 2.19E+06 9.12E+04 - - - 4.4748 0.9948 221125_WJC_METTL3_EV_vs_WT_F09.13309.13309.3 0.0822 Jun-60 R.EALLSSAVDHGSDEVK.F "sp|P78371|TCPB_HUMAN,tr|F8VQ14|F8VQ14_HUMAN,tr|F5GWF6|F5GWF6_HUMAN" 3 1655.8002 0.54 132252 13309 3 1655.80183 552.9407 T-complex protein 1 subunit beta OS=Homo sapiens OX=9606 GN=CCT2 PE=1 SV=4 4.31 2558.4 - 83245.4 - - - 0.9572 - 1.255 0.281 - 35.4 1 2 0 0.0016 16 0 0 0 1.27E+06 2.34E+06 - - - 2.2552 0.9847 221125_WJC_METTL3_EV_vs_WT_F09.13310.13310.2 0.234 16-Jul K.SPLQSVVVR[166.11].R "sp|Q9Y2W1|TR150_HUMAN,tr|A0A3B3ITZ9|A0A3B3ITZ9_HUMAN" 2 993.5847 2.59 132253 13310 2 993.586506 497.7996 Thyroid hormone receptor-associated protein 3 OS=Homo sapiens OX=9606 GN=THRAP3 PE=1 SV=2 9.47 2558.5 - 116568 - - - 1.868 - 1.386 0.116 - 157.4 1 2 0 0.0019 9 0 0 0 7.57E+06 2.92E+06 - - - 0.8415 0.9998 221125_WJC_METTL3_EV_vs_WT_F09.13318.13318.3 1.23E-05 Nov-60 R.EALLSSAVDHGSDEVK[136.11].F "sp|P78371|TCPB_HUMAN,tr|F8VQ14|F8VQ14_HUMAN,tr|F5GWF6|F5GWF6_HUMAN" 3 1663.8144 0.54 132259 13318 3 1663.818962 555.6121 T-complex protein 1 subunit beta OS=Homo sapiens OX=9606 GN=CCT2 PE=1 SV=4 4.31 2559.5 - 119302 - - - 2.7148 - 2.276 0.429 - 173.7 1 2 0 0.0045 16 0 0 0 1.27E+06 2.34E+06 - - - 5.4319 0.987 221125_WJC_METTL3_EV_vs_WT_F09.13319.13319.4 0.00217 Jun-90 R.GTFHDDR[166.11]DDGVDYWAK[136.11].R "tr|H0YF63|H0YF63_HUMAN,tr|E9PK91|E9PK91_HUMAN" 2 1913.8299 2.49 132260 13319 4 1913.838992 479.4648 Bcl-2-associated transcription factor 1 (Fragment) OS=Homo sapiens OX=9606 GN=BCLAF1 PE=1 SV=1 4.28 2559.6 - 79568.6 - - - 4.7376 - 1.305 0.378 - 27.2 1 2 1 0.0091 16 0 0 0 1.19E+07 4.78E+06 - - - 2.6074 0.9968 221125_WJC_METTL3_EV_vs_WT_F09.13324.13324.3 0.115 Jun-60 R.GTFHDDRDDGVDYWAK.R "tr|H0YF63|H0YF63_HUMAN,tr|E9PK91|E9PK91_HUMAN" 2 1895.8075 2.34 132263 13324 3 1895.811114 632.9431 Bcl-2-associated transcription factor 1 (Fragment) OS=Homo sapiens OX=9606 GN=BCLAF1 PE=1 SV=1 4.28 2560.5 - 167226 - - - 1.93 - 1.482 0.404 - 34.8 1 2 1 0.0037 16 0 0 0 1.01E+07 4.31E+06 - - - 4.0526 0.9988 221125_WJC_METTL3_EV_vs_WT_F09.13333.13333.2 0.000626 20-Nov K.LSAMMGAVAEK[136.11].K "sp|Q86U44|MTA70_HUMAN,tr|F5H6D8|F5H6D8_HUMAN,tr|H0YFV6|H0YFV6_HUMAN,tr|B4DTN4|B4DTN4_HUMAN" 4 1114.5606 0.08 132270 13333 2 1114.565059 558.2876 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 6 2561.7 - 174870 - - - 3.9989 - 2.276 0.482 - 329.2 1 2 0 0.0045 11 0 0 0 1.12E+07 1.37E+08 - - - 4.8245 0.9994 221125_WJC_METTL3_EV_vs_WT_F09.13336.13336.4 3.37E-05 Oct-90 R.GTFHDDRDDGVDYWAK.R "tr|H0YF63|H0YF63_HUMAN,tr|E9PK91|E9PK91_HUMAN" 2 1895.8075 2.49 132271 13336 4 1895.810919 474.9591 Bcl-2-associated transcription factor 1 (Fragment) OS=Homo sapiens OX=9606 GN=BCLAF1 PE=1 SV=1 4.28 2562.1 - 406645 - - - 1.8272 - 1.9 0.422 - 43.4 1 2 1 0.0035 16 0 0 0 1.19E+07 4.78E+06 - - - 3.1242 1 221125_WJC_METTL3_EV_vs_WT_F09.13338.13338.3 1.77E-06 15/56 R.STSHK[136.11]PDEIYGMIER[166.11].L sp|Q86U44|MTA70_HUMAN 1 1779.8581 0.001 132273 13338 3 1779.860678 594.2933 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 5.42 2562.4 - 434355 - - - 1.4743 - 2.872 0.513 - 275 1 2 0 0.0026 15 0 0 0 0.00E+00 6.91E+06 - - - 7.0116 1 221125_WJC_METTL3_EV_vs_WT_F09.13339.13339.3 2.02E-07 Nov-88 K.SEYSELDEDESQAPYDPNGKPER.F sp|P19387|RPB3_HUMAN 1 2654.1256 2.06 132274 13339 3 2654.129819 885.7158 DNA-directed RNA polymerase II subunit RPB3 OS=Homo sapiens OX=9606 GN=POLR2C PE=1 SV=2 3.89 2562.6 - 91786.7 - - - 1.5843 - 2.276 0.636 - 82.4 1 2 0 0.0042 23 0 0 0 5.51E+06 2.67E+06 - - - 7.559 0.9994 221125_WJC_METTL3_EV_vs_WT_F09.13341.13341.3 0.000519 Jun-88 K.SEYSELDEDESQAPYDPNGK[136.11]PER[166.11].F sp|P19387|RPB3_HUMAN 1 2672.1481 2.06 132276 13341 3 2672.15671 891.7233 DNA-directed RNA polymerase II subunit RPB3 OS=Homo sapiens OX=9606 GN=POLR2C PE=1 SV=2 3.89 2562.8 - 50715.4 - - - 3.2281 - 1.421 0.499 - 29.5 1 2 0 0.0086 23 0 0 0 5.51E+06 2.67E+06 - - - 4.9252 0.9999 221125_WJC_METTL3_EV_vs_WT_F09.13344.13344.4 0.000993 15/84 R.STSHK[136.11]PDEIYGMIER[166.11].L sp|Q86U44|MTA70_HUMAN 1 1779.8581 0.01 132277 13344 4 1779.860444 445.9718 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 5.42 2563.2 - 556458 - - - 1.3428 - 2.547 0.428 - 175.3 1 2 0 0.0024 15 0 0 0 6.42E+04 4.79E+06 - - - 3.2852 0.9999 221125_WJC_METTL3_EV_vs_WT_F09.13350.13350.4 2.03E-07 11/120 K.GDSLSLK[136.11]GETVNDC[160.03]HAEIISR[166.11].R "sp|P55265|DSRAD_HUMAN,tr|A0A3B3IRQ9|A0A3B3IRQ9_HUMAN,tr|A0A3B3ISU1|A0A3B3ISU1_HUMAN,tr|A0A7P0Z4K3|A0A7P0Z4K3_HUMAN,tr|A0A7P0Z4F9|A0A7P0Z4F9_HUMAN" 5 2318.1291 0.83 132281 13350 4 2318.129754 580.5396 Double-stranded RNA-specific adenosine deaminase OS=Homo sapiens OX=9606 GN=ADAR PE=1 SV=4 4.75 2564.1 - 148985 - - - 0.2631 - 2.321 0.569 - 68.5 1 2 1 0.0006 21 0 0 0 2.31E+06 2.78E+06 - - - 4.4568 1 221125_WJC_METTL3_EV_vs_WT_F09.13359.13359.3 1.19E-12 14/124 K.EAPAEGEAAEPGSPTAAEGEAASAASSTSSPK.A sp|P29966|MARCS_HUMAN 1 2914.2952 1.88 132288 13359 3 2914.299962 972.439 Myristoylated alanine-rich C-kinase substrate OS=Homo sapiens OX=9606 GN=MARCKS PE=1 SV=4 3.9 2565.3 - 72093.8 - - - 1.6344 - 3.282 0.746 - 132.5 1 2 0 0.0048 32 0 0 0 7.08E+06 3.77E+06 - - - 9.59 0.9984 221125_WJC_METTL3_EV_vs_WT_F09.13363.13363.3 3.68E-05 13/76 K.STTPPPAEPVSLPQEPPKPR.V tr|A0A7I2V647|A0A7I2V647_HUMAN 1 2124.1215 5.19 132291 13363 3 2124.131183 709.0478 Ras GTPase-activating protein-binding protein 2 OS=Homo sapiens OX=9606 GN=G3BP2 PE=1 SV=1 5.86 2565.9 - 157986 - - - 4.5496 - 2.406 0.382 - 170.4 1 2 0 0.0097 20 0 0 0 6.09E+06 1.17E+06 - - - 4.9262 0.9999 221125_WJC_METTL3_EV_vs_WT_F09.13377.13377.2 6.43E-07 13/28 R.STSHK[136.11]PDEIYGMIER[166.11].L sp|Q86U44|MTA70_HUMAN 1 1779.8581 0.001 132301 13377 2 1779.857827 890.9363 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 5.42 2567.7 - 240059 - - - -0.1275 - 2.009 0.561 - 346.1 1 2 0 -0.0002 15 0 0 0 0.00E+00 9.21E+08 - - - 4.8996 0.9996 221125_WJC_METTL3_EV_vs_WT_F09.13406.13406.3 0.00531 Nov-56 R.STSHKPDEIYGMIER.L sp|Q86U44|MTA70_HUMAN 1 1761.8356 0 132317 13406 3 1761.832277 588.2858 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 5.42 2571.7 - 658230 - - - -1.877 - 1.972 0.369 - 95.2 1 2 0 -0.0033 15 0 0 0 8.69E+07 3.01E+10 - - - 4.425 0.9793 221125_WJC_METTL3_EV_vs_WT_F09.13423.13423.3 8.07E-05 15/48 T.SHK[136.11]PDEIYGMIER[166.11].L sp|Q86U44|MTA70_HUMAN 1 1591.7783 0 132327 13423 3 1591.771442 531.6001 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 5.42 2573.7 - 524682 - - - -4.3379 - 2.775 0.515 - 353 1 1 0 -0.0069 13 0 0 0 2.51E+04 3.15E+07 - - - 7.0471 1 221125_WJC_METTL3_EV_vs_WT_F09.13426.13426.2 4.51E-08 14/22 R.FLEQQNQVLQTK.W "sp|Q7Z794|K2C1B_HUMAN,sp|P04264|K2C1_HUMAN,sp|P35908|K22E_HUMAN" 3 1474.778 999 132328 13426 2 1474.775646 738.3963 "Keratin, type II cytoskeletal 1b OS=Homo sapiens OX=9606 GN=KRT77 PE=1 SV=3" 6 2574.1 - 853336 - - - -1.5914 - 2.759 0.583 - 681.2 1 2 0 -0.0023 12 0 0 0 5.82E+07 0.00E+00 - - - 6.0166 0.9989 221125_WJC_METTL3_EV_vs_WT_F09.13437.13437.2 0.00269 28-Jul R.STSHKPDEIYGMIER[166.11].L sp|Q86U44|MTA70_HUMAN 1 1771.8439 - 132332 13437 2 1771.840481 886.9292 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 5.42 2575.5 - 303856 - - - -1.9037 - 1.64 0.359 - 98.1 1 2 0 -0.0034 15 0 0 0 - - - - - 2.9077 0.9993 221125_WJC_METTL3_EV_vs_WT_F09.13459.13459.2 9.47E-07 28-Sep R.STSHK[136.11]PDEIYGMIER.L sp|Q86U44|MTA70_HUMAN 1 1769.8498 - 132337 13459 2 1769.843714 885.9322 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 5.42 2578.8 - 631040 - - - -3.4297 - 1.854 0.581 - 186.2 1 2 0 -0.0061 15 0 0 0 - - - - - 4.8481 0.9998 221125_WJC_METTL3_EV_vs_WT_F09.13470.13470.3 3.80E-06 Dec-40 R.LVNHFVEEFK[136.11]R[166.11].K "sp|P0DMV8|HS71A_HUMAN,sp|P0DMV9|HS71B_HUMAN,tr|V9GZ37|V9GZ37_HUMAN,tr|A0A0G2JIW1|A0A0G2JIW1_HUMAN" 4 1434.7739 0.07 132342 13470 3 1434.769317 479.2652 Heat shock 70 kDa protein 1A OS=Homo sapiens OX=9606 GN=HSPA1A PE=1 SV=1 6.76 2580.3 - 574587 - - - -3.1622 - 2.377 0.425 - 301.5 1 2 0 -0.0045 11 0 0 0 3.20E+06 4.69E+07 - - - 5.7368 0.9992 221125_WJC_METTL3_EV_vs_WT_F09.13474.13474.3 5.65E-07 18/72 R.QAQQER[166.11]DELADEIANSSGK[136.11].G sp|P35579|MYH9_HUMAN 1 2105.9944 1.07 132343 13474 3 2105.987822 703.0054 Myosin-9 OS=Homo sapiens OX=9606 GN=MYH9 PE=1 SV=4 4.18 2580.8 - 1.34E+06 - - - -3.1349 - 3.116 0.427 - 387.3 1 2 1 -0.0066 19 0 0 0 1.56E+08 1.46E+08 - - - 6.0911 0.9999 221125_WJC_METTL3_EV_vs_WT_F09.13476.13476.3 1.81E-07 19/72 R.QAQQERDELADEIANSSGK.G sp|P35579|MYH9_HUMAN 1 2087.972 1.07 132344 13476 3 2087.96885 696.9979 Myosin-9 OS=Homo sapiens OX=9606 GN=MYH9 PE=1 SV=4 4.18 2581.1 - 1.30E+06 - - - -1.4866 - 3.598 0.491 - 478.2 1 2 1 -0.0031 19 0 0 0 1.57E+08 1.46E+08 - - - 7.1589 0.9832 221125_WJC_METTL3_EV_vs_WT_F09.13480.13480.3 0.0402 Sep-36 R.RKPFYPALIR.Y "sp|O00746|NDKM_HUMAN,tr|Q4TT34|Q4TT34_HUMAN,tr|H0Y6J0|H0Y6J0_HUMAN,tr|F2Z2X0|F2Z2X0_HUMAN,tr|A2IDC9|A2IDC9_HUMAN" 5 1259.7503 1.56 132345 13480 3 1259.745417 420.924 "Nucleoside diphosphate kinase, mitochondrial OS=Homo sapiens OX=9606 GN=NME4 PE=1 SV=1" 11 2581.6 - 449744 - - - -3.846 - 1.805 0.218 - 129.8 1 2 0 -0.0048 10 0 0 0 2.04E+07 1.31E+07 - - - 2.6938 0.9251 221125_WJC_METTL3_EV_vs_WT_F09.13490.13490.3 0.078 Jul-72 K.DIGYNMTR[166.11]MPNLMGHENQR[166.11].E sp|Q9ULW2|FZD10_HUMAN 1 2296.0414 0.37 132348 13490 3 2296.035043 766.3544 Frizzled-10 OS=Homo sapiens OX=9606 GN=FZD10 PE=1 SV=1 6.75 2583 - 624119 - - - -2.7752 - 1.343 0.261 - 22 1 2 1 -0.0064 19 0 0 0 9.79E+06 2.63E+07 - - - 2.1727 0.9999 221125_WJC_METTL3_EV_vs_WT_F09.13514.13514.4 0.00032 Dec-90 K.AQVQLDSDHLEEDIHR.L "sp|P07197|NFM_HUMAN,tr|E7ESP9|E7ESP9_HUMAN,tr|E7EMV2|E7EMV2_HUMAN" 3 1903.9024 1.03 132359 13514 4 1903.899773 476.9829 Neurofilament medium polypeptide OS=Homo sapiens OX=9606 GN=NEFM PE=1 SV=3 4.42 2586.1 - 613440 - - - -1.3893 - 2.041 0.424 - 112.9 1 2 0 -0.0026 16 0 0 0 1.79E+07 1.73E+07 - - - 3.1671 0.9999 221125_WJC_METTL3_EV_vs_WT_F09.13515.13515.3 2.15E-05 16/76 K.DGLNQTTIPVSPPSTTKPSR.A "sp|Q71RC2|LARP4_HUMAN,tr|X6RLN4|X6RLN4_HUMAN" 2 2095.0909 2.01 132360 13515 3 2095.086651 699.3709 La-related protein 4 OS=Homo sapiens OX=9606 GN=LARP4 PE=1 SV=3 8.75 2586.3 - 397759 - - - -2.0505 - 2.732 0.481 - 227.9 1 2 0 -0.0043 20 0 0 0 1.34E+07 6.68E+06 - - - 6.3397 0.9996 221125_WJC_METTL3_EV_vs_WT_F09.13518.13518.3 1.92E-05 14/68 R.GK[136.11]VEIDQQQLTQQQLNGN.- "sp|Q8IWS0|PHF6_HUMAN,tr|A0A0D9SGE8|A0A0D9SGE8_HUMAN" 2 2048.0378 0.64 132361 13518 3 2048.031821 683.6865 PHD finger protein 6 OS=Homo sapiens OX=9606 GN=PHF6 PE=1 SV=1 4.37 2586.7 - 614312 - - - -2.9174 - 2.694 0.524 - 285.9 1 2 1 -0.006 18 0 0 0 8.84E+06 1.38E+07 - - - 6.8482 0.9798 221125_WJC_METTL3_EV_vs_WT_F09.13519.13519.2 2.62 12-Jun K.STELLIR.K "sp|Q5TEC6|H3PS2_HUMAN,sp|Q16695|H31T_HUMAN,sp|P84243|H33_HUMAN,sp|Q6NXT2|H3C_HUMAN,sp|Q71DI3|H32_HUMAN,sp|P68431|H31_HUMAN,tr|B4DEB1|B4DEB1_HUMAN,tr|K7EK07|K7EK07_HUMAN,tr|K7ES00|K7ES00_HUMAN,tr|K7EP01|K7EP01_HUMAN,tr|K7EMV3|K7EMV3_HUMAN,tr|A0A590UJJ6|A0A590UJJ6_HUMAN" 12 830.4862 0.55 132362 13519 2 830.484334 416.2504 Histone HIST2H3PS2 OS=Homo sapiens OX=9606 GN=H3-2 PE=1 SV=1 5.72 2586.8 - 407120 - - - -2.2083 - 1.394 0.09 - 244.7 1 2 0 -0.0018 7 0 0 0 7.96E+06 1.44E+07 - - - 0.7577 0.9998 221125_WJC_METTL3_EV_vs_WT_F09.13524.13524.3 0.000915 Dec-68 R.GKVEIDQQQLTQQQLNGN.- "sp|Q8IWS0|PHF6_HUMAN,tr|A0A0D9SGE8|A0A0D9SGE8_HUMAN" 2 2040.0236 0.42 132365 13524 3 2040.022608 681.0151 PHD finger protein 6 OS=Homo sapiens OX=9606 GN=PHF6 PE=1 SV=1 4.37 2587.4 - 416719 - - - -0.4843 - 2.499 0.454 - 201.6 1 2 1 -0.001 18 0 0 0 9.17E+06 2.19E+07 - - - 5.882 0.9438 221125_WJC_METTL3_EV_vs_WT_F09.13525.13525.4 0.0236 9/102 R.EAQSLISAAIEPDKKEEK.R "sp|Q05519|SRS11_HUMAN,tr|Q5T760|Q5T760_HUMAN,tr|Q5T757|Q5T757_HUMAN" 3 1985.0317 4.79 132366 13525 4 1985.021645 497.2652 Serine\arginine-rich splicing factor 11 OS=Homo sapiens OX=9606 GN=SRSF11 PE=1 SV=1 4.59 2587.6 - 117555 - - - -5.0659 - 1.881 0.296 - 61.7 1 2 1 -0.0101 18 0 0 0 1.11E+07 2.32E+06 - - - 2.016 1 221125_WJC_METTL3_EV_vs_WT_F09.13526.13526.3 1.61E-07 16/60 K.AQVQLDSDHLEEDIHR.L "sp|P07197|NFM_HUMAN,tr|E7ESP9|E7ESP9_HUMAN,tr|E7EMV2|E7EMV2_HUMAN" 3 1903.9024 3.07 132367 13526 3 1903.901085 635.6414 Neurofilament medium polypeptide OS=Homo sapiens OX=9606 GN=NEFM PE=1 SV=3 4.42 2587.7 - 190233 - - - -0.7001 - 3.543 0.622 - 311.1 1 2 0 -0.0013 16 0 0 0 4.93E+06 1.61E+06 - - - 8.7201 0.9306 221125_WJC_METTL3_EV_vs_WT_F09.13527.13527.2 0.0235 May-34 R.GK[136.11]VEIDQQQLTQQQLNGN.- "sp|Q8IWS0|PHF6_HUMAN,tr|A0A0D9SGE8|A0A0D9SGE8_HUMAN" 2 2048.0378 0.6 132368 13527 2 2048.033873 1025.0262 PHD finger protein 6 OS=Homo sapiens OX=9606 GN=PHF6 PE=1 SV=1 4.37 2587.8 - 116078 - - - -1.9155 - 1.165 0.271 - 67.5 1 2 1 -0.0039 18 0 0 0 1.36E+06 2.27E+06 - - - 1.4168 1 221125_WJC_METTL3_EV_vs_WT_F09.13531.13531.4 5.05E-08 21/120 K.K[136.11]LASQGDSISSQLGPIHPPPR[166.11].T "sp|Q92945|FUBP2_HUMAN,tr|M0R0I5|M0R0I5_HUMAN,tr|M0R0C6|M0R0C6_HUMAN,tr|A0A087WTP3|A0A087WTP3_HUMAN" 4 2202.1876 1.37 132370 13531 4 2202.182234 551.5542 Far upstream element-binding protein 2 OS=Homo sapiens OX=9606 GN=KHSRP PE=1 SV=4 8.75 2588.4 - 319809 - - - -2.4299 - 3.853 0.598 - 234.3 1 2 0 -0.0054 21 0 0 0 1.41E+07 1.03E+07 - - - 4.8755 0.9999 221125_WJC_METTL3_EV_vs_WT_F09.13532.13532.3 1.18E-06 Aug-88 K.C[160.03]PEPYLPPPC[160.03]PPEHC[160.03]PPPPC[160.03]QDK.C sp|Q9BYE4|SPR2G_HUMAN 1 2768.1855 66.44 132371 13532 3 2768.178014 923.7358 Small proline-rich protein 2G OS=Homo sapiens OX=9606 GN=SPRR2G PE=3 SV=1 4.65 2588.5 - 126064 - - - -2.7173 - 2.048 0.601 - 57.7 1 2 0 -0.0075 23 0 0 0 2.98E+06 4.48E+04 - - - 6.9202 1 221125_WJC_METTL3_EV_vs_WT_F09.13533.13533.4 4.00E-08 18/120 K.KLASQGDSISSQLGPIHPPPR.T "sp|Q92945|FUBP2_HUMAN,tr|M0R0I5|M0R0I5_HUMAN,tr|M0R0C6|M0R0C6_HUMAN,tr|A0A087WTP3|A0A087WTP3_HUMAN" 4 2184.1651 1.37 132372 13533 4 2184.160336 547.0486 Far upstream element-binding protein 2 OS=Homo sapiens OX=9606 GN=KHSRP PE=1 SV=4 8.75 2588.6 - 828892 - - - -2.188 - 3.753 0.557 - 185.8 1 2 0 -0.0048 21 0 0 0 1.41E+07 1.03E+07 - - - 4.5101 0.9998 221125_WJC_METTL3_EV_vs_WT_F09.13540.13540.3 7.95E-05 Dec-56 K.DDTHK[136.11]VDVINFAQNK[136.11].A "sp|O15027|SC16A_HUMAN,tr|A0A3F2YNX0|A0A3F2YNX0_HUMAN,tr|A0A3F2YNZ0|A0A3F2YNZ0_HUMAN,tr|X6RGP5|X6RGP5_HUMAN,tr|F1T0I1|F1T0I1_HUMAN" 5 1758.8872 1 132377 13540 3 1758.884765 587.303 Protein transport protein Sec16A OS=Homo sapiens OX=9606 GN=SEC16A PE=1 SV=4 5.3 2589.4 - 203116 - - - -1.3634 - 2.241 0.485 - 197.1 1 2 1 -0.0024 15 0 0 0 8.26E+06 8.26E+06 - - - 6.0522 0.9999 221125_WJC_METTL3_EV_vs_WT_F09.13543.13543.4 1.99E-06 14/102 K.KYEDIC[160.03]PSTHNMDVPNIK.R "sp|P63241|IF5A1_HUMAN,sp|Q9GZV4|IF5A2_HUMAN,sp|Q6IS14|IF5AL_HUMAN,tr|C9J4W5|C9J4W5_HUMAN,tr|I3L397|I3L397_HUMAN,tr|I3L504|I3L504_HUMAN,tr|C9J7B5|C9J7B5_HUMAN,tr|F8WCJ1|F8WCJ1_HUMAN" 8 2159.998 0.95 132380 13543 4 2159.99732 541.0068 Eukaryotic translation initiation factor 5A-1 OS=Homo sapiens OX=9606 GN=EIF5A PE=1 SV=2 5.38 2589.8 - 352241 - - - -0.3032 - 2.538 0.466 - 153.5 1 2 0 -0.0007 18 0 0 0 1.34E+07 1.41E+07 - - - 3.6009 1 221125_WJC_METTL3_EV_vs_WT_F09.13546.13546.3 1.45E-05 8/104 R.TGSPSSSASAC[160.03]SPGGMLSSAGGAPEGK.D sp|Q96F45|ZN503_HUMAN 1 2394.0428 2.92 132383 13546 3 2394.046865 799.0215 Zinc finger protein 503 OS=Homo sapiens OX=9606 GN=ZNF503 PE=1 SV=1 5.66 2590.2 - 151799 - - - 1.7176 - 1.604 0.627 - 47.8 1 2 0 0.0041 27 0 0 0 1.80E+06 6.15E+05 - - - 6.6163 0.9999 221125_WJC_METTL3_EV_vs_WT_F09.13549.13549.3 6.20E-07 Aug-68 K.K[136.11]YEDIC[160.03]PSTHNMDVPNIK[136.11].R "sp|P63241|IF5A1_HUMAN,sp|Q9GZV4|IF5A2_HUMAN,sp|Q6IS14|IF5AL_HUMAN,tr|C9J4W5|C9J4W5_HUMAN,tr|I3L397|I3L397_HUMAN,tr|I3L504|I3L504_HUMAN,tr|C9J7B5|C9J7B5_HUMAN,tr|F8WCJ1|F8WCJ1_HUMAN" 8 2176.0264 1.32 132384 13549 3 2176.021759 726.3494 Eukaryotic translation initiation factor 5A-1 OS=Homo sapiens OX=9606 GN=EIF5A PE=1 SV=2 5.38 2590.7 - 188771 - - - -2.1213 - 1.944 0.554 - 64.1 1 2 0 -0.0046 18 0 0 0 6.76E+06 5.11E+06 - - - 6.3706 1 221125_WJC_METTL3_EV_vs_WT_F09.13551.13551.3 4.54E-05 14/76 K.DGLNQTTIPVSPPSTTK[136.11]PSR[166.11].A "sp|Q71RC2|LARP4_HUMAN,tr|X6RLN4|X6RLN4_HUMAN" 2 2113.1134 1.78 132386 13551 3 2113.109553 705.3784 La-related protein 4 OS=Homo sapiens OX=9606 GN=LARP4 PE=1 SV=3 8.75 2590.9 - 229939 - - - -1.8286 - 2.817 0.532 - 156.3 1 2 0 -0.0039 20 0 0 0 1.23E+08 6.94E+07 - - - 6.9828 1 221125_WJC_METTL3_EV_vs_WT_F09.13552.13552.3 5.47E-08 Sep-68 K.KYEDIC[160.03]PSTHNMDVPNIK.R "sp|P63241|IF5A1_HUMAN,sp|Q9GZV4|IF5A2_HUMAN,sp|Q6IS14|IF5AL_HUMAN,tr|C9J4W5|C9J4W5_HUMAN,tr|I3L397|I3L397_HUMAN,tr|I3L504|I3L504_HUMAN,tr|C9J7B5|C9J7B5_HUMAN,tr|F8WCJ1|F8WCJ1_HUMAN" 8 2159.998 1.29 132387 13552 3 2159.999443 721.0066 Eukaryotic translation initiation factor 5A-1 OS=Homo sapiens OX=9606 GN=EIF5A PE=1 SV=2 5.38 2591 - 200756 - - - 0.6796 - 2.018 0.638 - 80 1 2 0 0.0015 18 0 0 0 6.76E+06 5.25E+06 - - - 7.401 0.9999 221125_WJC_METTL3_EV_vs_WT_F09.13556.13556.3 1.19E-05 Sep-80 K.K[136.11]LASQGDSISSQLGPIHPPPR[166.11].T "sp|Q92945|FUBP2_HUMAN,tr|M0R0I5|M0R0I5_HUMAN,tr|M0R0C6|M0R0C6_HUMAN,tr|A0A087WTP3|A0A087WTP3_HUMAN" 4 2202.1876 1.98 132391 13556 3 2202.184923 735.0698 Far upstream element-binding protein 2 OS=Homo sapiens OX=9606 GN=KHSRP PE=1 SV=4 8.75 2591.6 - 86195.3 - - - -1.2088 - 1.887 0.502 - 56.8 1 2 0 -0.0027 21 0 0 0 4.97E+06 2.51E+06 - - - 5.6584 1 221125_WJC_METTL3_EV_vs_WT_F09.13560.13560.3 4.58E-05 15/108 K.QIAESANSSSPQSSAGGKPAMSYASALR.A "sp|P42694|HELZ_HUMAN,tr|J3QS41|J3QS41_HUMAN" 2 2752.3086 3.16 132393 13560 3 2752.308377 918.4435 Probable helicase with zinc finger domain OS=Homo sapiens OX=9606 GN=HELZ PE=1 SV=2 8.59 2592 - 217996 - - - -0.0887 - 3.038 0.578 - 122.4 1 2 0 -0.0002 28 0 0 0 1.09E+07 3.43E+06 - - - 7.5405 0.9497 221125_WJC_METTL3_EV_vs_WT_F09.13561.13561.4 1.82 Jul-84 K.DDTHK[136.11]VDVINFAQNK[136.11].A "sp|O15027|SC16A_HUMAN,tr|A0A3F2YNX0|A0A3F2YNX0_HUMAN,tr|A0A3F2YNZ0|A0A3F2YNZ0_HUMAN,tr|X6RGP5|X6RGP5_HUMAN,tr|F1T0I1|F1T0I1_HUMAN" 5 1758.8872 1.25 132394 13561 4 1758.885167 440.7291 Protein transport protein Sec16A OS=Homo sapiens OX=9606 GN=SEC16A PE=1 SV=4 5.3 2592.2 - 144308 - - - -1.1348 - 0.912 0.216 - 17.2 1 2 1 -0.002 15 0 0 0 3.16E+06 2.53E+06 - - - 1.0726 1 221125_WJC_METTL3_EV_vs_WT_F09.13566.13566.3 1.30E-08 24/76 K.R[166.11]GLLQDDAHPTLVTYADHSK[136.11].L "sp|Q86U44|MTA70_HUMAN,tr|F5H6D8|F5H6D8_HUMAN,tr|H0YFV6|H0YFV6_HUMAN,tr|B4DTN4|B4DTN4_HUMAN" 4 2254.1461 0 132397 13566 3 2254.145085 752.3893 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 5.99 2592.8 - 872137 - - - -0.4569 - 4.215 0.594 - 798.5 1 2 0 -0.001 20 0 0 0 4.87E+06 3.25E+09 - - - 8.6524 1 221125_WJC_METTL3_EV_vs_WT_F09.13567.13567.3 2.58E-08 17/56 K.DDTHKVDVINFAQNK.A "sp|O15027|SC16A_HUMAN,tr|A0A3F2YNX0|A0A3F2YNX0_HUMAN,tr|A0A3F2YNZ0|A0A3F2YNZ0_HUMAN,tr|X6RGP5|X6RGP5_HUMAN,tr|F1T0I1|F1T0I1_HUMAN" 5 1742.8588 1 132398 13567 3 1742.858799 581.9602 Protein transport protein Sec16A OS=Homo sapiens OX=9606 GN=SEC16A PE=1 SV=4 5.3 2593 - 492476 - - - 0.0207 - 3.33 0.587 - 502.4 1 2 1 0 15 0 0 0 8.26E+06 8.26E+06 - - - 8.2235 0.9998 221125_WJC_METTL3_EV_vs_WT_F09.13569.13569.2 0.000391 22-Dec K.NAGVEGSLIVEK.L "sp|P10809|CH60_HUMAN,tr|A0A7I2V2X6|A0A7I2V2X6_HUMAN,tr|A0A7I2YQK6|A0A7I2YQK6_HUMAN,tr|A0A7I2V599|A0A7I2V599_HUMAN" 4 1214.6507 1.56 132400 13569 2 1214.650051 608.3326 "60 kDa heat shock protein, mitochondrial OS=Homo sapiens OX=9606 GN=HSPD1 PE=1 SV=2" 4.53 2593.2 - 228990 - - - -0.5071 - 2.168 0.464 - 500.3 1 2 0 -0.0006 12 0 0 0 7.57E+06 4.84E+06 - - - 4.5039 0.9998 221125_WJC_METTL3_EV_vs_WT_F09.13573.13573.4 0.000696 13/84 R.STSHK[136.11]PDEIYGMIER[166.11].L sp|Q86U44|MTA70_HUMAN 1 1779.8581 0.01 132403 13573 4 1779.85591 445.9718 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 5.42 2593.7 - 1.24E+07 - - - -1.2046 - 2.389 0.375 - 131.9 1 2 0 -0.0021 15 0 0 0 3.23E+06 4.55E+08 - - - 2.801 0.9999 221125_WJC_METTL3_EV_vs_WT_F09.13575.13575.3 1.10E-06 Sep-92 K.IKDDGPSQSESATETAMTLPSESR.V sp|Q9H9A6|LRC40_HUMAN 1 2536.1599 4.1 132404 13575 3 2536.158308 846.3939 Leucine-rich repeat-containing protein 40 OS=Homo sapiens OX=9606 GN=LRRC40 PE=1 SV=1 4.18 2593.9 - 124721 - - - -0.6242 - 1.974 0.615 - 59.5 1 2 1 -0.0016 24 0 0 0 7.16E+06 1.75E+06 - - - 6.9757 1 221125_WJC_METTL3_EV_vs_WT_F09.13580.13580.4 1.10E-06 12/102 K.K[136.11]YEDIC[160.03]PSTHNMDVPNIK[136.11].R "sp|P63241|IF5A1_HUMAN,sp|Q9GZV4|IF5A2_HUMAN,sp|Q6IS14|IF5AL_HUMAN,tr|C9J4W5|C9J4W5_HUMAN,tr|I3L397|I3L397_HUMAN,tr|I3L504|I3L504_HUMAN,tr|C9J7B5|C9J7B5_HUMAN,tr|F8WCJ1|F8WCJ1_HUMAN" 8 2176.0264 0.95 132407 13580 4 2176.024778 545.0139 Eukaryotic translation initiation factor 5A-1 OS=Homo sapiens OX=9606 GN=EIF5A PE=1 SV=2 5.38 2594.6 - 487834 - - - -0.7339 - 2.61 0.62 - 126.3 1 2 0 -0.0016 18 0 0 0 1.34E+07 1.41E+07 - - - 4.9507 0.9999 221125_WJC_METTL3_EV_vs_WT_F09.13582.13582.4 2.17E-06 Dec-96 K.NR[166.11]EELGFR[166.11]PEYSASQLK[136.11].G "sp|P09874|PARP1_HUMAN,tr|A0A7I2V5E9|A0A7I2V5E9_HUMAN,tr|A0A7I2V625|A0A7I2V625_HUMAN,tr|A0A7I2V3E1|A0A7I2V3E1_HUMAN" 4 2051.043 0.88 132408 13582 4 2051.039746 513.768 Poly [ADP-ribose] polymerase 1 OS=Homo sapiens OX=9606 GN=PARP1 PE=1 SV=4 6.23 2594.8 - 227919 - - - -1.6075 - 2.278 0.513 - 117 1 2 1 -0.0033 17 0 0 0 1.25E+07 1.42E+07 - - - 3.9761 0.9998 221125_WJC_METTL3_EV_vs_WT_F09.13584.13584.4 4.47E-07 13/96 K.NREELGFRPEYSASQLK.G "sp|P09874|PARP1_HUMAN,tr|A0A7I2V5E9|A0A7I2V5E9_HUMAN,tr|A0A7I2V625|A0A7I2V625_HUMAN,tr|A0A7I2V3E1|A0A7I2V3E1_HUMAN" 4 2023.0123 0.88 132409 13584 4 2023.016276 506.7604 Poly [ADP-ribose] polymerase 1 OS=Homo sapiens OX=9606 GN=PARP1 PE=1 SV=4 6.23 2595 - 299152 - - - 1.9639 - 2.525 0.525 - 141.3 1 2 1 0.004 17 0 0 0 1.25E+07 1.42E+07 - - - 4.1161 1 221125_WJC_METTL3_EV_vs_WT_F09.13585.13585.3 9.04E-06 13/108 K.QIAESANSSSPQSSAGGK[136.11]PAMSYASALR[166.11].A "sp|P42694|HELZ_HUMAN,tr|J3QS41|J3QS41_HUMAN" 2 2770.3311 3.16 132410 13585 3 2770.32716 924.451 Probable helicase with zinc finger domain OS=Homo sapiens OX=9606 GN=HELZ PE=1 SV=2 8.59 2595.2 - 211657 - - - -1.419 - 2.727 0.547 - 76.7 1 2 0 -0.0039 28 0 0 0 1.09E+07 3.43E+06 - - - 6.9454 0.9953 221125_WJC_METTL3_EV_vs_WT_F09.13588.13588.3 1.73E-06 Sep-52 D.DAHPTLVTYADHSK[136.11].L "sp|Q86U44|MTA70_HUMAN,tr|F5H6D8|F5H6D8_HUMAN,tr|H0YFV6|H0YFV6_HUMAN,tr|B4DTN4|B4DTN4_HUMAN" 4 1561.7616 0.001 132413 13588 3 1561.758222 521.5945 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 5.98 2595.6 - 103707 - - - -2.1764 - 2.05 0.58 - 92.5 1 1 0 -0.0034 14 0 0 0 0.00E+00 4.05E+07 - - - 6.9132 0.9989 221125_WJC_METTL3_EV_vs_WT_F09.13605.13605.3 3.53E-08 16/56 Q.DDAHPTLVTYADHSK[136.11].L "sp|Q86U44|MTA70_HUMAN,tr|F5H6D8|F5H6D8_HUMAN,tr|H0YFV6|H0YFV6_HUMAN,tr|B4DTN4|B4DTN4_HUMAN" 4 1676.7886 0.01 132421 13605 3 1676.787672 559.9368 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 5.13 2597.8 - 2.29E+06 - - - -0.532 - 2.745 0.624 - 352.1 1 1 0 -0.0009 15 0 0 0 5.11E+06 3.56E+08 - - - 8.1316 0.9899 221125_WJC_METTL3_EV_vs_WT_F09.13608.13608.2 0.000129 28-Aug R.STSHK[136.11]PDEIYGMIER[166.11].L sp|Q86U44|MTA70_HUMAN 1 1779.8581 0.001 132424 13608 2 1779.847601 890.9363 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 5.42 2598.2 - 358758 - - - -5.8729 - 1.49 0.489 - 137.6 1 2 0 -0.0105 15 0 0 0 0.00E+00 1.24E+07 - - - 3.6299 1 221125_WJC_METTL3_EV_vs_WT_F09.13611.13611.4 7.50E-08 21/114 K.R[166.11]GLLQDDAHPTLVTYADHSK[136.11].L "sp|Q86U44|MTA70_HUMAN,tr|F5H6D8|F5H6D8_HUMAN,tr|H0YFV6|H0YFV6_HUMAN,tr|B4DTN4|B4DTN4_HUMAN" 4 2254.1461 0.01 132425 13611 4 2254.140242 564.5438 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 5.99 2598.6 - 1.93E+08 - - - -2.6054 - 3.538 0.561 - 424 1 2 0 -0.0059 20 0 0 0 1.59E+08 2.16E+10 - - - 4.5298 0.8792 221125_WJC_METTL3_EV_vs_WT_F09.13629.13629.4 0.122 10/108 R.GLLQDDAHPTLVTYADHSK[136.11].L "sp|Q86U44|MTA70_HUMAN,tr|F5H6D8|F5H6D8_HUMAN,tr|H0YFV6|H0YFV6_HUMAN,tr|B4DTN4|B4DTN4_HUMAN" 4 2088.0367 0.01 132430 13629 4 2088.032749 523.0165 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 5.13 2601.1 - 604805 - - - -1.908 - 1.64 0.118 - 65.9 1 2 0 -0.004 19 0 0 0 3.43E+05 2.34E+07 - - - 0.4193 0.9146 221125_WJC_METTL3_EV_vs_WT_F09.13630.13630.4 0.0118 Sep-78 R.QRPAEIKDYSPYFK.T sp|P02533|K1C14_HUMAN 1 1740.8835 97.9 132431 13630 4 1740.877009 436.2282 "Keratin, type I cytoskeletal 14 OS=Homo sapiens OX=9606 GN=KRT14 PE=1 SV=4" 8.43 2601.2 - 441704 - - - -3.7406 - 1.652 0.236 - 53.7 1 2 1 -0.0065 14 0 0 0 1.30E+07 1.32E+05 - - - 1.461 0.8836 221125_WJC_METTL3_EV_vs_WT_F09.13637.13637.3 4.07E-07 Nov-48 D.AHPTLVTYADHSK[136.11].L "sp|Q86U44|MTA70_HUMAN,tr|F5H6D8|F5H6D8_HUMAN,tr|H0YFV6|H0YFV6_HUMAN,tr|B4DTN4|B4DTN4_HUMAN" 4 1446.7347 0.05 132433 13637 3 1446.725876 483.2522 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 6.96 2602.2 - 342897 - - - -6.084 - 2.001 0.525 - 154.3 1 1 0 -0.0088 13 0 0 0 9.39E+05 2.03E+07 - - - 6.2715 0.9999 221125_WJC_METTL3_EV_vs_WT_F09.13640.13640.3 9.18E-08 20/56 R.STSHK[136.11]PDEIYGMIER[166.11].L sp|Q86U44|MTA70_HUMAN 1 1779.8581 0 132434 13640 3 1779.851602 594.2933 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 5.42 2602.6 - 6.54E+06 - - - -3.625 - 3.373 0.561 - 461.2 1 2 0 -0.0065 15 0 0 0 2.35E+06 9.09E+08 - - - 7.9653 0.989 221125_WJC_METTL3_EV_vs_WT_F09.13648.13648.2 0.304 14-Jul K.IEISELNR.V "sp|P04264|K2C1_HUMAN,sp|P35908|K22E_HUMAN" 2 972.524 123.89 132435 13648 2 972.522266 487.2693 "Keratin, type II cytoskeletal 1 OS=Homo sapiens OX=9606 GN=KRT1 PE=1 SV=6" 4.53 2603.9 - 947840 - - - -1.7933 - 1.57 0.079 - 148.2 1 2 0 -0.0017 8 0 0 0 6.41E+07 5.18E+05 - - - 0.9844 0.944 221125_WJC_METTL3_EV_vs_WT_F09.13657.13657.3 0.000253 Dec-60 L.QDDAHPTLVTYADHSK[136.11].L "sp|Q86U44|MTA70_HUMAN,tr|F5H6D8|F5H6D8_HUMAN,tr|H0YFV6|H0YFV6_HUMAN,tr|B4DTN4|B4DTN4_HUMAN" 4 1804.8471 0.06 132438 13657 3 1804.839387 602.623 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 5.13 2605 - 2.53E+06 - - - -4.2968 - 2.195 0.465 - 185.7 1 1 0 -0.0078 16 0 0 0 1.52E+07 2.36E+08 - - - 5.7394 0.9996 221125_WJC_METTL3_EV_vs_WT_F09.13662.13662.2 8.59E-06 13/38 K.R[166.11]GLLQDDAHPTLVTYADHSK[136.11].L "sp|Q86U44|MTA70_HUMAN,tr|F5H6D8|F5H6D8_HUMAN,tr|H0YFV6|H0YFV6_HUMAN,tr|B4DTN4|B4DTN4_HUMAN" 4 2254.1461 0.001 132439 13662 2 2254.139623 1128.0803 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 5.99 2605.8 - 220458 - - - -2.88 - 2.398 0.596 - 219.3 1 2 0 -0.0065 20 0 0 0 0.00E+00 1.58E+07 - - - 5.5913 0.9919 221125_WJC_METTL3_EV_vs_WT_F09.13663.13663.2 2.25E-06 20-Sep H.PTLVTYADHSK[136.11].L "sp|Q86U44|MTA70_HUMAN,tr|F5H6D8|F5H6D8_HUMAN,tr|H0YFV6|H0YFV6_HUMAN,tr|B4DTN4|B4DTN4_HUMAN" 4 1238.6387 0.05 132440 13663 2 1238.638017 620.3266 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 7.16 2605.9 - 308736 - - - -0.5127 - 2.225 0.473 - 300.6 1 1 0 -0.0006 11 0 0 0 8.10E+05 1.51E+07 - - - 4.6979 0.9998 221125_WJC_METTL3_EV_vs_WT_F09.13670.13670.2 0.000643 20-Sep K.IGGIGTVPVGR.V "sp|Q05639|EF1A2_HUMAN,sp|P68104|EF1A1_HUMAN,sp|Q5VTE0|EF1A3_HUMAN,tr|A0A7I2V659|A0A7I2V659_HUMAN,tr|A0A7I2V3H3|A0A7I2V3H3_HUMAN,tr|A0A2U3TZH3|A0A2U3TZH3_HUMAN,tr|A0A7I2V5N4|A0A7I2V5N4_HUMAN,tr|A0A087WVQ9|A0A087WVQ9_HUMAN" 8 1024.6029 11.29 132443 13670 2 1024.602299 513.3087 Elongation factor 1-alpha 2 OS=Homo sapiens OX=9606 GN=EEF1A2 PE=1 SV=1 9.75 2606.8 - 544890 - - - -0.6149 - 1.952 0.451 - 236 1 2 0 -0.0006 11 0 0 0 6.82E+07 6.04E+06 - - - 4.1813 0.9998 221125_WJC_METTL3_EV_vs_WT_F09.13671.13671.4 9.43E-07 Oct-90 K.KHLEINPDHPIVETLR.Q sp|P08238|HS90B_HUMAN 1 1910.0374 0.99 132444 13671 4 1910.031482 478.5166 Heat shock protein HSP 90-beta OS=Homo sapiens OX=9606 GN=HSP90AB1 PE=1 SV=4 6.01 2606.9 - 482732 - - - -3.0963 - 1.972 0.467 - 73.2 1 2 0 -0.0059 16 0 0 0 6.77E+07 6.85E+07 - - - 3.5283 0.9999 221125_WJC_METTL3_EV_vs_WT_F09.13677.13677.4 2.70E-06 17/90 K.K[136.11]HLEINPDHPIVETLR[166.11].Q sp|P08238|HS90B_HUMAN 1 1928.0599 0.98 132446 13677 4 1928.055643 483.0222 Heat shock protein HSP 90-beta OS=Homo sapiens OX=9606 GN=HSP90AB1 PE=1 SV=4 6.01 2607.8 - 388199 - - - -2.1903 - 2.63 0.509 - 219.3 1 2 0 -0.0042 16 0 0 0 6.77E+07 6.87E+07 - - - 3.9958 0.9918 221125_WJC_METTL3_EV_vs_WT_F09.13705.13705.2 5.17E-06 30-Nov Q.ELALTQSVGGDSSADR[166.11].L "sp|Q86U44|MTA70_HUMAN,tr|H0YFV6|H0YFV6_HUMAN" 2 1614.7725 0.001 132454 13705 2 1614.771022 808.3935 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 4.03 2611.8 - 335702 - - - -0.8924 - 2.362 0.502 - 111.5 1 1 0 -0.0014 16 0 0 0 0.00E+00 1.56E+07 - - - 4.8615 0.9996 221125_WJC_METTL3_EV_vs_WT_F09.13712.13712.3 0.00131 Oct-60 K.KHLEINPDHPIVETLR.Q sp|P08238|HS90B_HUMAN 1 1910.0374 1.04 132456 13712 3 1910.032066 637.6864 Heat shock protein HSP 90-beta OS=Homo sapiens OX=9606 GN=HSP90AB1 PE=1 SV=4 6.01 2612.8 - 195679 - - - -2.7905 - 1.891 0.44 - 77.6 1 2 0 -0.0053 16 0 0 0 1.24E+07 1.19E+07 - - - 5.0788 1 221125_WJC_METTL3_EV_vs_WT_F09.13732.13732.3 6.10E-07 20/92 R.DGEDQTQDTELVETRPAGDGTFQK.W "sp|P04439|HLAA_HUMAN,sp|P01893|HLAH_HUMAN,sp|P10321|HLAC_HUMAN,tr|A0A1W2PP77|A0A1W2PP77_HUMAN,tr|A0A140T941|A0A140T941_HUMAN,tr|A0A1W2PQS8|A0A1W2PQS8_HUMAN,tr|A0A140T921|A0A140T921_HUMAN,tr|A0A1W2PNZ7|A0A1W2PNZ7_HUMAN,tr|A0A0G2JI36|A0A0G2JI36_HUMAN,tr|A0A140T8W8|A0A140T8W8_HUMAN,tr|Q9GJ45|Q9GJ45_HUMAN,tr|O19617|O19617_HUMAN,tr|Q53Z42|Q53Z42_HUMAN,tr|Q5RJ27|Q5RJ27_HUMAN,tr|Q53YP1|Q53YP1_HUMAN,tr|Q5RIP0|Q5RIP0_HUMAN,tr|Q5SRN5|Q5SRN5_HUMAN,tr|A0A1W2PS24|A0A1W2PS24_HUMAN,tr|A0A0G2JIF2|A0A0G2JIF2_HUMAN,tr|A0A1W2PQD0|A0A1W2PQD0_HUMAN,tr|A0A1W2PRZ0|A0A1W2PRZ0_HUMAN,tr|A0A0G2JH50|A0A0G2JH50_HUMAN,tr|A0A140T9U0|A0A140T9U0_HUMAN,tr|A0A140T955|A0A140T955_HUMAN,tr|A0A0G2JPD3|A0A0G2JPD3_HUMAN,tr|A0A140T9W2|A0A140T9W2_HUMAN,tr|O78179|O78179_HUMAN,tr|A0A140T913|A0A140T913_HUMAN,tr|A2AEA2|A2AEA2_HUMAN,tr|A0A1W2PPQ2|A0A1W2PPQ2_HUMAN,tr|Q5SPM2|Q5SPM2_HUMAN,tr|Q5SUL5|Q5SUL5_HUMAN,tr|A0A140T8Y4|A0A140T8Y4_HUMAN,tr|A0A140T975|A0A140T975_HUMAN,tr|A2BF26|A2BF26_HUMAN,tr|A0A140T933|A0A140T933_HUMAN,tr|A0A140T9H5|A0A140T9H5_HUMAN,tr|A0A1W2PS56|A0A1W2PS56_HUMAN,tr|A0A0G2JIF0|A0A0G2JIF0_HUMAN,tr|A0A1W2PSE7|A0A1W2PSE7_HUMAN,tr|Q5QT33|Q5QT33_HUMAN,tr|A0A140T9J9|A0A140T9J9_HUMAN,tr|A0A1W2PRT9|A0A1W2PRT9_HUMAN,tr|A0A140T9B3|A0A140T9B3_HUMAN,tr|A0A1W2PPF8|A0A1W2PPF8_HUMAN,tr|A0A1W2PRX1|A0A1W2PRX1_HUMAN,tr|A0A140T937|A0A140T937_HUMAN,tr|Q5SRN7|Q5SRN7_HUMAN,tr|A0A1W2PR61|A0A1W2PR61_HUMAN,tr|A0A140T912|A0A140T912_HUMAN,tr|A0A140T962|A0A140T962_HUMAN,tr|A0A140T9M0|A0A140T9M0_HUMAN,tr|A0A140T9I0|A0A140T9I0_HUMAN,tr|A0A140T9U8|A0A140T9U8_HUMAN,tr|A0A140T9X5|A0A140T9X5_HUMAN,tr|A0A1W2PS39|A0A1W2PS39_HUMAN,tr|A0A140T9Z6|A0A140T9Z6_HUMAN,tr|A0A1W2PR11|A0A1W2PR11_HUMAN,tr|A0A140T930|A0A140T930_HUMAN,tr|B0UXQ0|B0UXQ0_HUMAN,tr|A0A0G2JL56|A0A0G2JL56_HUMAN" 61 2636.1838 1.7 132466 13732 3 2636.181382 879.7352 "HLA class I histocompatibility antigen, A alpha chain OS=Homo sapiens OX=9606 GN=HLA-A PE=1 SV=2" 3.9 2615.7 - 624956 - - - -0.9165 - 3.693 0.649 - 313 1 2 0 -0.0024 24 0 0 0 1.84E+07 1.08E+07 - - - 8.8094 0.9999 221125_WJC_METTL3_EV_vs_WT_F09.13738.13738.3 1.38E-05 18/76 K.DGLNQTTIPVSPPSTTKPSR.A "sp|Q71RC2|LARP4_HUMAN,tr|X6RLN4|X6RLN4_HUMAN" 2 2095.0909 1.78 132469 13738 3 2095.087024 699.3709 La-related protein 4 OS=Homo sapiens OX=9606 GN=LARP4 PE=1 SV=3 8.75 2616.5 - 1.00E+06 - - - -1.8725 - 2.718 0.495 - 341.5 1 2 0 -0.0039 20 0 0 0 1.23E+08 6.94E+07 - - - 6.4834 0.9999 221125_WJC_METTL3_EV_vs_WT_F09.13748.13748.3 2.76E-09 15/60 K.K[136.11]HLEINPDHPIVETLR[166.11].Q sp|P08238|HS90B_HUMAN 1 1928.0599 1.04 132475 13748 3 1928.055748 643.6939 Heat shock protein HSP 90-beta OS=Homo sapiens OX=9606 GN=HSP90AB1 PE=1 SV=4 6.01 2617.7 - 208682 - - - -2.1358 - 2.885 0.452 - 241.7 1 2 0 -0.0041 16 0 0 0 1.24E+07 1.19E+07 - - - 6.2968 0.7927 221125_WJC_METTL3_EV_vs_WT_F09.13780.13780.2 0.158 12-Jul R.K[136.11]IELFGR[166.11].P sp|Q86U44|MTA70_HUMAN 1 879.5297 0.001 132491 13780 2 879.528155 440.7721 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 8.75 2622.1 - 314975 - - - -1.7657 - 1.325 0.234 - 241.1 1 1 0 -0.0016 7 0 0 0 0.00E+00 1.89E+07 - - - 1.6605 0.9999 221125_WJC_METTL3_EV_vs_WT_F09.13788.13788.3 4.98E-06 18/76 K.R[166.11]GLLQDDAHPTLVTYADHSK[136.11].L "sp|Q86U44|MTA70_HUMAN,tr|F5H6D8|F5H6D8_HUMAN,tr|H0YFV6|H0YFV6_HUMAN,tr|B4DTN4|B4DTN4_HUMAN" 4 2254.1461 0 132494 13788 3 2254.141553 752.3893 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 5.99 2623.1 - 1.19E+07 - - - -2.0238 - 3.092 0.443 - 329.4 1 2 0 -0.0046 20 0 0 0 4.87E+06 3.25E+09 - - - 6.2163 0.9969 221125_WJC_METTL3_EV_vs_WT_F09.13793.13793.3 0.000892 Nov-68 R.HIQQVDC[160.03]SGNDLEQLHIK[136.11].V "sp|P52948|NUP98_HUMAN,tr|H7C3P6|H7C3P6_HUMAN,tr|H0YCT1|H0YCT1_HUMAN" 3 2141.0415 0.67 132497 13793 3 2141.029469 714.6878 Nuclear pore complex protein Nup98-Nup96 OS=Homo sapiens OX=9606 GN=NUP98 PE=1 SV=4 5.21 2623.8 - 195086 - - - -5.6202 - 2.09 0.415 - 148.5 1 2 0 -0.012 18 0 0 0 7.58E+06 1.14E+07 - - - 4.9991 0.9995 221125_WJC_METTL3_EV_vs_WT_F09.13797.13797.3 7.26E-05 6/104 K.GLAAEDSGGDSK[136.11]DLSEVSETTESTDVK[136.11].D sp|P41227|NAA10_HUMAN 1 2742.2538 0.55 132499 13797 3 2742.247805 915.0919 N-alpha-acetyltransferase 10 OS=Homo sapiens OX=9606 GN=NAA10 PE=1 SV=1 3.85 2624.2 - 220934 - - - -2.1818 - 1.842 0.536 - 25.6 1 2 1 -0.006 27 0 0 0 1.39E+06 2.52E+06 - - - 5.9196 1 221125_WJC_METTL3_EV_vs_WT_F09.13799.13799.3 2.20E-08 18/68 R.HIQQVDC[160.03]SGNDLEQLHIK.V "sp|P52948|NUP98_HUMAN,tr|H7C3P6|H7C3P6_HUMAN,tr|H0YCT1|H0YCT1_HUMAN" 3 2133.0273 0.73 132500 13799 3 2133.023604 712.0164 Nuclear pore complex protein Nup98-Nup96 OS=Homo sapiens OX=9606 GN=NUP98 PE=1 SV=4 5.21 2624.4 - 203750 - - - -1.7337 - 3.795 0.695 - 533.2 1 2 0 -0.0037 18 0 0 0 7.45E+06 1.02E+07 - - - 9.6085 0.9999 221125_WJC_METTL3_EV_vs_WT_F09.13803.13803.4 0.000113 17/84 R.STSHK[136.11]PDEIYGMIER[166.11].L sp|Q86U44|MTA70_HUMAN 1 1779.8581 0.01 132503 13803 4 1779.855083 445.9718 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 5.42 2624.9 - 904979 - - - -1.6692 - 2.675 0.463 - 226.4 1 2 0 -0.003 15 0 0 0 3.37E+05 3.93E+07 - - - 3.6072 1 221125_WJC_METTL3_EV_vs_WT_F09.13812.13812.4 2.90E-07 12/102 R.HIQQVDC[160.03]SGNDLEQLHIK.V "sp|P52948|NUP98_HUMAN,tr|H7C3P6|H7C3P6_HUMAN,tr|H0YCT1|H0YCT1_HUMAN" 3 2133.0273 2.3 132509 13812 4 2133.025836 534.2641 Nuclear pore complex protein Nup98-Nup96 OS=Homo sapiens OX=9606 GN=NUP98 PE=1 SV=4 5.21 2626.1 - 416064 - - - -0.6873 - 2.982 0.643 - 120.8 1 2 0 -0.0015 18 0 0 0 5.58E+06 2.42E+06 - - - 5.1965 0.9949 221125_WJC_METTL3_EV_vs_WT_F09.13813.13813.4 0.119 6/120 R.GC[160.03]SK[136.11]PLC[160.03]C[160.03]SC[160.03]ALLDSSHSELK[136.11].C "sp|P29590|PML_HUMAN,tr|H3BT57|H3BT57_HUMAN" 2 2424.0877 0.67 132510 13813 4 2424.087096 607.0292 Protein PML OS=Homo sapiens OX=9606 GN=PML PE=1 SV=3 6.72 2626.2 - 280778 - - - -0.238 - 1.032 0.25 - 16.8 1 2 0 -0.0006 21 0 0 0 2.92E+06 4.36E+06 - - - 1.4123 0.9999 221125_WJC_METTL3_EV_vs_WT_F09.13814.13814.4 2.49E-05 11/102 R.HIQQVDC[160.03]SGNDLEQLHIK[136.11].V "sp|P52948|NUP98_HUMAN,tr|H7C3P6|H7C3P6_HUMAN,tr|H0YCT1|H0YCT1_HUMAN" 3 2141.0415 2.3 132511 13814 4 2141.035125 536.2677 Nuclear pore complex protein Nup98-Nup96 OS=Homo sapiens OX=9606 GN=NUP98 PE=1 SV=4 5.21 2626.4 - 328281 - - - -2.9785 - 1.905 0.547 - 55.2 1 2 0 -0.0064 18 0 0 0 5.58E+06 2.42E+06 - - - 4.2061 0.9993 221125_WJC_METTL3_EV_vs_WT_F09.13830.13830.3 0.000389 Sep-64 K.DKQNKPTGFALGSIEGR.V "sp|P78406|RAE1L_HUMAN,tr|E9PQ57|E9PQ57_HUMAN" 2 1816.9432 1.83 132520 13830 3 1816.940684 606.655 mRNA export factor OS=Homo sapiens OX=9606 GN=RAE1 PE=1 SV=1 8.59 2628.4 - 232554 - - - -1.3633 - 2.098 0.409 - 44.6 1 2 1 -0.0025 17 0 0 0 3.71E+07 2.03E+07 - - - 4.9712 0.9862 221125_WJC_METTL3_EV_vs_WT_F09.13834.13834.2 0.000133 Sep-32 S.QELALTQSVGGDSSADR[166.11].L "sp|Q86U44|MTA70_HUMAN,tr|H0YFV6|H0YFV6_HUMAN" 2 1742.831 0.001 132524 13834 2 1742.829952 872.4228 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 4.03 2628.9 - 69319.4 - - - -0.6248 - 1.593 0.51 - 141.2 1 1 0 -0.0011 17 0 0 0 0.00E+00 3.90E+06 - - - 3.9523 0.9964 221125_WJC_METTL3_EV_vs_WT_F09.13838.13838.3 0.0008 Nov-64 K.DK[136.11]QNK[136.11]PTGFALGSIEGR[166.11].V "sp|P78406|RAE1L_HUMAN,tr|E9PQ57|E9PQ57_HUMAN" 2 1842.9798 1.83 132526 13838 3 1842.973861 615.3339 mRNA export factor OS=Homo sapiens OX=9606 GN=RAE1 PE=1 SV=1 8.59 2629.3 - 293426 - - - -3.2393 - 2.263 0.366 - 143.6 1 2 1 -0.006 17 0 0 0 3.71E+07 2.03E+07 - - - 4.6821 0.9036 221125_WJC_METTL3_EV_vs_WT_F09.13840.13840.4 0.828 Oct-96 K.DKQNKPTGFALGSIEGR.V "sp|P78406|RAE1L_HUMAN,tr|E9PQ57|E9PQ57_HUMAN" 2 1816.9432 1.67 132528 13840 4 1816.940691 455.2431 mRNA export factor OS=Homo sapiens OX=9606 GN=RAE1 PE=1 SV=1 8.59 2629.6 - 269148 - - - -1.3594 - 1.929 0.159 - 68.2 1 2 1 -0.0025 17 0 0 0 3.08E+07 1.84E+07 - - - 0.8374 0.9729 221125_WJC_METTL3_EV_vs_WT_F09.13858.13858.4 0.103 Jun-90 R.SK[136.11]VDEAVAVLQAHQAK[136.11].E "sp|Q9H361|PABP3_HUMAN,sp|P11940|PABP1_HUMAN,tr|H0YAS6|H0YAS6_HUMAN,tr|H0YB75|H0YB75_HUMAN,tr|H0YAS7|H0YAS7_HUMAN,tr|A0A7I2YQE4|A0A7I2YQE4_HUMAN,tr|A0A7I2V649|A0A7I2V649_HUMAN,tr|H0YC10|H0YC10_HUMAN,tr|H0YAR2|H0YAR2_HUMAN,tr|E7ERJ7|E7ERJ7_HUMAN,tr|A0A7I2YQ88|A0A7I2YQ88_HUMAN,tr|A0A087WTT1|A0A087WTT1_HUMAN,tr|A0A7I2YQ90|A0A7I2YQ90_HUMAN,tr|A0A7I2V4N4|A0A7I2V4N4_HUMAN,tr|E7EQV3|E7EQV3_HUMAN" 15 1708.9443 1.53 132541 13858 4 1708.944876 428.2433 Polyadenylate-binding protein 3 OS=Homo sapiens OX=9606 GN=PABPC3 PE=1 SV=2 6.47 2632.1 - 108246 - - - 0.347 - 1.133 0.233 - 15.6 1 2 1 0.0006 16 0 0 0 5.65E+06 3.71E+06 - - - 1.2979 0.9997 221125_WJC_METTL3_EV_vs_WT_F09.13859.13859.3 0.000667 Sep-88 K.EAASSSSGTQPAPPAPASPWDSK.K sp|Q9H7N4|SFR19_HUMAN 1 2225.0237 0.71 132542 13859 3 2225.026884 742.6818 "Splicing factor, arginine\serine-rich 19 OS=Homo sapiens OX=9606 GN=SCAF1 PE=1 SV=3" 4.37 2632.2 - 84510.4 - - - 1.4508 - 1.748 0.425 - 58.4 1 2 0 0.0032 23 0 0 0 2.16E+06 3.04E+06 - - - 4.5876 1 221125_WJC_METTL3_EV_vs_WT_F09.13867.13867.3 5.46E-08 19/56 R.STSHK[136.11]PDEIYGMIER[166.11].L sp|Q86U44|MTA70_HUMAN 1 1779.8581 0.001 132547 13867 3 1779.859399 594.2933 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 5.42 2633.3 - 636865 - - - 0.7557 - 3.417 0.588 - 441.2 1 2 0 0.0013 15 0 0 0 0.00E+00 7.32E+07 - - - 8.3015 0.9907 221125_WJC_METTL3_EV_vs_WT_F09.13869.13869.4 0.0636 13/96 K.DK[136.11]QNK[136.11]PTGFALGSIEGR[166.11].V "sp|P78406|RAE1L_HUMAN,tr|E9PQ57|E9PQ57_HUMAN" 2 1842.9798 1.67 132548 13869 4 1842.980912 461.7522 mRNA export factor OS=Homo sapiens OX=9606 GN=RAE1 PE=1 SV=1 8.59 2633.5 - 797534 - - - 0.5866 - 2.382 0.25 - 119.9 1 2 1 0.0011 17 0 0 0 3.08E+07 1.84E+07 - - - 1.703 0.9476 221125_WJC_METTL3_EV_vs_WT_F09.13871.13871.4 0.0621 Aug-90 R.SKVDEAVAVLQAHQAK.E "sp|Q9H361|PABP3_HUMAN,sp|P11940|PABP1_HUMAN,tr|H0YAS6|H0YAS6_HUMAN,tr|H0YB75|H0YB75_HUMAN,tr|H0YAS7|H0YAS7_HUMAN,tr|A0A7I2YQE4|A0A7I2YQE4_HUMAN,tr|A0A7I2V649|A0A7I2V649_HUMAN,tr|H0YC10|H0YC10_HUMAN,tr|H0YAR2|H0YAR2_HUMAN,tr|E7ERJ7|E7ERJ7_HUMAN,tr|A0A7I2YQ88|A0A7I2YQ88_HUMAN,tr|A0A087WTT1|A0A087WTT1_HUMAN,tr|A0A7I2YQ90|A0A7I2YQ90_HUMAN,tr|A0A7I2V4N4|A0A7I2V4N4_HUMAN,tr|E7EQV3|E7EQV3_HUMAN" 15 1692.9159 1.53 132550 13871 4 1692.919427 424.2362 Polyadenylate-binding protein 3 OS=Homo sapiens OX=9606 GN=PABPC3 PE=1 SV=2 6.47 2633.7 - 125153 - - - 2.0934 - 1.489 0.215 - 32.2 1 2 1 0.0035 16 0 0 0 5.66E+06 3.71E+06 - - - 1.2366 0.9982 221125_WJC_METTL3_EV_vs_WT_F09.13894.13894.3 0.00712 Nov-52 K.SQIHDIVLVGGSTR[166.11].L "sp|P11142|HSP7C_HUMAN,tr|E9PNE6|E9PNE6_HUMAN,tr|A8K7Q2|A8K7Q2_HUMAN,tr|E9PKE3|E9PKE3_HUMAN,tr|E9PN89|E9PN89_HUMAN" 5 1490.8081 0.13 132566 13894 3 1490.813291 497.9433 Heat shock cognate 71 kDa protein OS=Homo sapiens OX=9606 GN=HSPA8 PE=1 SV=1 6.46 2636.9 - 216818 - - - 3.5082 - 2.017 0.339 - 162.5 1 2 0 0.0052 14 0 0 0 1.86E+06 1.45E+07 - - - 4.1826 0.9975 221125_WJC_METTL3_EV_vs_WT_F09.13911.13911.4 0.00253 12/120 K.FKDPNC[160.03]VGTVLASRPHTLDGR.N "sp|Q96EP5|DAZP1_HUMAN,tr|K7EK33|K7EK33_HUMAN,tr|K7EQ55|K7EQ55_HUMAN,tr|K7EQ02|K7EQ02_HUMAN" 4 2339.1804 1.14 132578 13911 4 2339.186969 585.8024 DAZ-associated protein 1 OS=Homo sapiens OX=9606 GN=DAZAP1 PE=1 SV=1 8.23 2639.1 - 376180 - - - 2.7877 - 1.635 0.384 - 81.4 1 2 1 0.0065 21 0 0 0 5.88E+06 5.18E+06 - - - 2.7291 0.9999 221125_WJC_METTL3_EV_vs_WT_F09.13912.13912.3 2.58E-07 Aug-52 K.K[136.11]GPGEVAGTVTGQK[136.11].R "sp|Q86U44|MTA70_HUMAN,tr|F5H6D8|F5H6D8_HUMAN,tr|H0YFV6|H0YFV6_HUMAN,tr|B4DTN4|B4DTN4_HUMAN" 4 1343.738 0.001 132579 13912 3 1343.741147 448.9199 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 8.59 2639.3 - 115874 - - - 2.3576 - 1.971 0.563 - 94.2 1 2 0 0.0032 14 0 0 0 0.00E+00 1.89E+06 - - - 6.6193 0.8742 221125_WJC_METTL3_EV_vs_WT_F09.13920.13920.3 0.00965 May-64 K.KILDSVGIEADDDRLNK.V sp|P05387|RLA2_HUMAN 1 1899.9902 1.44 132585 13920 3 1899.998985 634.3373 60S acidic ribosomal protein P2 OS=Homo sapiens OX=9606 GN=RPLP2 PE=1 SV=1 4.36 2640.4 - 89444.4 - - - 4.639 - 1.402 0.309 - 30.7 2 2 1 0.0088 17 0 0 0 3.58E+06 2.48E+06 - - - 2.6969 0.9997 221125_WJC_METTL3_EV_vs_WT_F09.13921.13921.3 1.84E-06 Sep-64 K.K[136.11]ILDSVGIEADDDR[166.11]LNK[136.11].V sp|P05387|RLA2_HUMAN 1 1926.0268 1.44 132586 13921 3 1926.031697 643.0162 60S acidic ribosomal protein P2 OS=Homo sapiens OX=9606 GN=RPLP2 PE=1 SV=1 4.36 2640.5 - 83508 - - - 2.5213 - 2.113 0.585 - 70.4 1 2 1 0.0049 17 0 0 0 3.58E+06 2.48E+06 - - - 6.9508 0.9998 221125_WJC_METTL3_EV_vs_WT_F09.13925.13925.4 1.16E-07 14/120 K.FK[136.11]DPNC[160.03]VGTVLASR[166.11]PHTLDGR[166.11].N "sp|Q96EP5|DAZP1_HUMAN,tr|K7EK33|K7EK33_HUMAN,tr|K7EQ55|K7EQ55_HUMAN,tr|K7EQ02|K7EQ02_HUMAN" 4 2367.2112 1.17 132588 13925 4 2367.219026 592.8101 DAZ-associated protein 1 OS=Homo sapiens OX=9606 GN=DAZAP1 PE=1 SV=1 8.23 2641.1 - 323357 - - - 3.3111 - 2.75 0.619 - 138.7 1 2 1 0.0078 21 0 0 0 6.07E+06 5.18E+06 - - - 4.9461 1 221125_WJC_METTL3_EV_vs_WT_F09.13926.13926.4 5.64E-11 17/168 R.R[166.11]ATAPVPTVGEGYGYGHESELSQASAAAR[166.11].N "sp|Q9BWF3|RBM4_HUMAN,tr|E9PB51|E9PB51_HUMAN" 2 2951.4277 1.22 132589 13926 4 2951.43505 738.8642 RNA-binding protein 4 OS=Homo sapiens OX=9606 GN=RBM4 PE=1 SV=1 5.5 2641.2 - 191228 - - - 2.5062 - 3.665 0.685 - 83.1 1 2 0 0.0074 29 0 0 0 3.94E+06 3.24E+06 - - - 5.5865 0.9987 221125_WJC_METTL3_EV_vs_WT_F09.13928.13928.4 0.0286 9/102 K.VFQGTDEQLNDLYHNHQR[166.11].T "sp|Q92878|RAD50_HUMAN,tr|E7EN38|E7EN38_HUMAN,tr|A0A494BZX5|A0A494BZX5_HUMAN,tr|A0A494C1B7|A0A494C1B7_HUMAN,tr|E7ESD9|E7ESD9_HUMAN,tr|A0A494C122|A0A494C122_HUMAN,tr|A0A494C0Y7|A0A494C0Y7_HUMAN,tr|A0A1W2PQ90|A0A1W2PQ90_HUMAN" 8 2223.0333 1.37 132591 13928 4 2223.039674 556.7656 DNA repair protein RAD50 OS=Homo sapiens OX=9606 GN=RAD50 PE=1 SV=1 5.21 2641.5 - 82614.1 - - - 2.8839 - 2.062 0.335 - 86.5 1 2 0 0.0064 18 0 0 0 2.14E+06 1.56E+06 - - - 2.388 0.9997 221125_WJC_METTL3_EV_vs_WT_F09.13929.13929.2 4.01E-06 26-Aug K.SQIHDIVLVGGSTR[166.11].L "sp|P11142|HSP7C_HUMAN,tr|E9PNE6|E9PNE6_HUMAN,tr|A8K7Q2|A8K7Q2_HUMAN,tr|E9PKE3|E9PKE3_HUMAN,tr|E9PN89|E9PN89_HUMAN" 5 1490.8081 0.001 132592 13929 2 1490.805315 746.4113 Heat shock cognate 71 kDa protein OS=Homo sapiens OX=9606 GN=HSPA8 PE=1 SV=1 6.46 2641.6 - 46607.5 - - - -1.842 - 1.993 0.504 - 202.1 1 2 0 -0.0027 14 0 0 0 0.00E+00 6.89E+05 - - - 4.4933 0.9942 221125_WJC_METTL3_EV_vs_WT_F09.13934.13934.4 4.95E-05 8/156 K.PSFAAESVGQSAEPPKPSVEPALQQHR.D "sp|Q6W2J9|BCOR_HUMAN,tr|H7BZ37|H7BZ37_HUMAN,tr|A1A564|A1A564_HUMAN,tr|H7C2V9|H7C2V9_HUMAN,tr|H7BYY2|H7BYY2_HUMAN,tr|H7C231|H7C231_HUMAN" 6 2843.4202 2.22 132595 13934 4 2843.425274 711.8623 BCL-6 corepressor OS=Homo sapiens OX=9606 GN=BCOR PE=1 SV=1 5.51 2642.3 - 87028.4 - - - 1.7771 - 1.942 0.513 - 25.9 1 1 0 0.0051 27 0 0 0 7.18E+05 3.24E+05 - - - 3.8974 0.9999 221125_WJC_METTL3_EV_vs_WT_F09.13939.13939.3 8.03E-06 Nov-76 K.HNVPDDGLPLQSQQLPQSGK[136.11].E "sp|Q9UBB9|TFP11_HUMAN,tr|H0Y4U8|H0Y4U8_HUMAN" 2 2165.0956 1.24 132598 13939 3 2165.100082 722.7058 Tuftelin-interacting protein 11 OS=Homo sapiens OX=9606 GN=TFIP11 PE=1 SV=1 5.21 2643.1 - 185480 - - - 2.0493 - 2.319 0.54 - 100.3 1 2 0 0.0044 20 0 0 0 9.07E+06 7.29E+06 - - - 6.5999 0.9983 221125_WJC_METTL3_EV_vs_WT_F09.13940.13940.4 0.00241 7/102 K.VFQGTDEQLNDLYHNHQR.T "sp|Q92878|RAD50_HUMAN,tr|E7EN38|E7EN38_HUMAN,tr|A0A494BZX5|A0A494BZX5_HUMAN,tr|A0A494C1B7|A0A494C1B7_HUMAN,tr|E7ESD9|E7ESD9_HUMAN,tr|A0A494C122|A0A494C122_HUMAN,tr|A0A494C0Y7|A0A494C0Y7_HUMAN,tr|A0A1W2PQ90|A0A1W2PQ90_HUMAN" 8 2213.025 1.37 132599 13940 4 2213.031194 554.2635 DNA repair protein RAD50 OS=Homo sapiens OX=9606 GN=RAD50 PE=1 SV=1 5.21 2643.2 - 124911 - - - 2.802 - 1.587 0.329 - 47.1 1 2 0 0.0062 18 0 0 0 2.15E+06 1.56E+06 - - - 2.2461 0.9999 221125_WJC_METTL3_EV_vs_WT_F09.13941.13941.3 2.70E-11 Dec-76 K.HNVPDDGLPLQSQQLPQSGK.E "sp|Q9UBB9|TFP11_HUMAN,tr|H0Y4U8|H0Y4U8_HUMAN" 2 2157.0814 1.25 132600 13941 3 2157.088878 720.0344 Tuftelin-interacting protein 11 OS=Homo sapiens OX=9606 GN=TFIP11 PE=1 SV=1 5.21 2643.3 - 216516 - - - 3.4459 - 2.66 0.642 - 132.2 1 2 0 0.0074 20 0 0 0 9.14E+06 7.29E+06 - - - 8.069 0.999 221125_WJC_METTL3_EV_vs_WT_F09.13942.13942.4 6.29E-05 Nov-96 K.K[136.11]ILDSVGIEADDDR[166.11]LNK[136.11].V sp|P05387|RLA2_HUMAN 1 1926.0268 1.51 132601 13942 4 1926.033417 482.514 60S acidic ribosomal protein P2 OS=Homo sapiens OX=9606 GN=RPLP2 PE=1 SV=1 4.36 2643.4 - 164296 - - - 3.4143 - 2.125 0.463 - 69.4 1 2 1 0.0066 17 0 0 0 2.60E+06 1.72E+06 - - - 3.5158 0.9997 221125_WJC_METTL3_EV_vs_WT_F09.13952.13952.2 1.15E-05 20-Aug R.EEAENTLQSFR.Q "sp|P08670|VIME_HUMAN,tr|B0YJC5|B0YJC5_HUMAN,tr|B0YJC4|B0YJC4_HUMAN" 3 1322.6103 2.66 132608 13952 2 1322.612437 662.3124 Vimentin OS=Homo sapiens OX=9606 GN=VIM PE=1 SV=4 4.25 2644.8 - 74440.1 - - - 1.6467 - 1.797 0.519 - 230.1 1 2 0 0.0022 11 0 0 0 2.13E+06 8.00E+05 - - - 4.4592 0.9964 221125_WJC_METTL3_EV_vs_WT_F09.13953.13953.3 0.0155 Aug-56 R.K[136.11]EYEQELSDDLHVER[166.11].Y "sp|Q7Z7F7|RM55_HUMAN,tr|X6R631|X6R631_HUMAN" 2 1906.9028 1.08 132609 13953 3 1906.911016 636.6415 "39S ribosomal protein L55, mitochondrial OS=Homo sapiens OX=9606 GN=MRPL55 PE=1 SV=1" 4.35 2644.9 - 65909.9 - - - 4.3316 - 1.85 0.354 - 91.1 1 2 0 0.0083 15 0 0 0 4.29E+06 3.97E+06 - - - 4.0897 0.9997 221125_WJC_METTL3_EV_vs_WT_F09.13957.13957.3 1.77E-05 Jul-96 K.LVC[160.03]SGENDNHGQIANLPSAVTSDQK[136.11].S sp|Q8WYP5|ELYS_HUMAN 1 2661.2544 1.3 132611 13957 3 2661.261526 888.0921 Protein ELYS OS=Homo sapiens OX=9606 GN=AHCTF1 PE=1 SV=3 4.54 2645.6 - 91628.8 - - - 2.6747 - 1.62 0.506 - 30 1 2 0 0.0071 25 0 0 0 1.26E+06 9.70E+05 - - - 5.2893 0.9999 221125_WJC_METTL3_EV_vs_WT_F09.13964.13964.3 0.000199 Sep-56 R.KEYEQELSDDLHVER.Y "sp|Q7Z7F7|RM55_HUMAN,tr|X6R631|X6R631_HUMAN" 2 1888.8803 1.1 132616 13964 3 1888.882588 630.634 "39S ribosomal protein L55, mitochondrial OS=Homo sapiens OX=9606 GN=MRPL55 PE=1 SV=1" 4.35 2646.6 - 131635 - - - 1.2187 - 2.101 0.469 - 145.3 1 2 0 0.0023 15 0 0 0 4.27E+06 3.88E+06 - - - 5.7055 0.8769 221125_WJC_METTL3_EV_vs_WT_F09.13965.13965.2 0.0591 22-May K.DHTPSQELALTQ.S "sp|Q86U44|MTA70_HUMAN,tr|H0YFV6|H0YFV6_HUMAN" 2 1338.6416 - 132617 13965 2 1338.640788 670.3281 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 4.35 2646.7 - 47679.1 - - - -0.576 - 1.199 0.296 - 84.8 1 1 0 -0.0008 12 0 0 0 - - - - - 1.7045 0.9579 221125_WJC_METTL3_EV_vs_WT_F09.13966.13966.3 0.000622 Aug-68 P.SQELALTQSVGGDSSADR[166.11].L "sp|Q86U44|MTA70_HUMAN,tr|H0YFV6|H0YFV6_HUMAN" 2 1829.8631 0.01 132618 13966 3 1829.867496 610.9616 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 4.03 2646.9 - 173081 - - - 2.4193 - 1.777 0.428 - 53.1 1 1 0 0.0044 18 0 0 0 5.60E+04 6.51E+06 - - - 4.7422 0.9999 221125_WJC_METTL3_EV_vs_WT_F09.13971.13971.4 1.41E-08 18/84 R.KEYEQELSDDLHVER.Y "sp|Q7Z7F7|RM55_HUMAN,tr|X6R631|X6R631_HUMAN" 2 1888.8803 1.35 132621 13971 4 1888.887026 473.2273 "39S ribosomal protein L55, mitochondrial OS=Homo sapiens OX=9606 GN=MRPL55 PE=1 SV=1" 4.35 2647.6 - 203230 - - - 3.5683 - 3.604 0.549 - 493.8 1 2 0 0.0067 15 0 0 0 6.36E+06 4.73E+06 - - - 4.4614 0.9999 221125_WJC_METTL3_EV_vs_WT_F09.13972.13972.4 1.17E-07 18/84 R.K[136.11]EYEQELSDDLHVER[166.11].Y "sp|Q7Z7F7|RM55_HUMAN,tr|X6R631|X6R631_HUMAN" 2 1906.9028 1.35 132622 13972 4 1906.909027 477.733 "39S ribosomal protein L55, mitochondrial OS=Homo sapiens OX=9606 GN=MRPL55 PE=1 SV=1" 4.35 2647.7 - 198895 - - - 3.2886 - 3.364 0.593 - 447.4 1 2 0 0.0063 15 0 0 0 6.39E+06 4.73E+06 - - - 4.8198 0.9873 221125_WJC_METTL3_EV_vs_WT_F09.13973.13973.3 0.0816 May-96 K.LVC[160.03]SGENDNHGQIANLPSAVTSDQK.S sp|Q8WYP5|ELYS_HUMAN 1 2653.2402 1.3 132623 13973 3 2653.244637 885.4207 Protein ELYS OS=Homo sapiens OX=9606 GN=AHCTF1 PE=1 SV=3 4.54 2647.8 - 109251 - - - 1.6693 - 1.029 0.299 - 15.3 1 2 0 0.0044 25 0 0 0 1.26E+06 9.70E+05 - - - 1.9381 0.9954 221125_WJC_METTL3_EV_vs_WT_F09.13975.13975.2 0.0306 20-May R.EEAENTLQSFR[166.11].Q "sp|P08670|VIME_HUMAN,tr|B0YJC5|B0YJC5_HUMAN,tr|B0YJC4|B0YJC4_HUMAN" 3 1332.6185 2.66 132625 13975 2 1332.620515 667.3165 Vimentin OS=Homo sapiens OX=9606 GN=VIM PE=1 SV=4 4.25 2648.1 - 49578.7 - - - 1.4903 - 1.193 0.277 - 65.9 1 2 0 0.002 11 0 0 0 2.13E+06 8.00E+05 - - - 1.5637 0.9694 221125_WJC_METTL3_EV_vs_WT_F09.13982.13982.3 0.00448 Jun-44 R.DLDELSR[166.11]YPEDK[136.11].L "sp|P43243|MATR3_HUMAN,tr|A8MXP9|A8MXP9_HUMAN,tr|D6R991|D6R991_HUMAN,tr|A0A0R4J2E8|A0A0R4J2E8_HUMAN,tr|D6REM6|D6REM6_HUMAN" 5 1496.7114 1.5 132630 13982 3 1496.71624 499.9111 Matrin-3 OS=Homo sapiens OX=9606 GN=MATR3 PE=1 SV=2 4.11 2649 - 80437.9 - - - 3.2518 - 1.278 0.342 - 33.8 1 2 1 0.0049 12 0 0 0 9.87E+06 6.60E+06 - - - 3.0315 1 221125_WJC_METTL3_EV_vs_WT_F09.13990.13990.2 2.15E-07 30-Sep R.HDSEQDNSDNNTIFVQ.G sp|P35637|FUS_HUMAN 1 1861.7715 - 132636 13990 2 1861.775852 931.893 RNA-binding protein FUS OS=Homo sapiens OX=9606 GN=FUS PE=1 SV=1 3.84 2650.1 - 119520 - - - 2.3569 - 2.016 0.696 - 155.4 1 1 0 0.0044 16 0 0 0 - - - - - 5.904 0.9378 221125_WJC_METTL3_EV_vs_WT_F09.13991.13991.3 0.0234 Jun-60 R.HDSEQDNSDNNTIFVQ.G sp|P35637|FUS_HUMAN 1 1861.7715 - 132637 13991 3 1861.771719 621.5978 RNA-binding protein FUS OS=Homo sapiens OX=9606 GN=FUS PE=1 SV=1 3.84 2650.3 - 67089.1 - - - 0.137 - 1.276 0.402 - 40.8 1 1 0 0.0003 16 0 0 0 - - - - - 3.6472 0.9961 221125_WJC_METTL3_EV_vs_WT_F09.13996.13996.3 0.00311 Oct-44 R.DLDELSRYPEDK.L "sp|P43243|MATR3_HUMAN,tr|A8MXP9|A8MXP9_HUMAN,tr|D6R991|D6R991_HUMAN,tr|A0A0R4J2E8|A0A0R4J2E8_HUMAN,tr|D6REM6|D6REM6_HUMAN" 5 1478.6889 1.49 132640 13996 3 1478.69396 493.9036 Matrin-3 OS=Homo sapiens OX=9606 GN=MATR3 PE=1 SV=2 4.11 2651 - 144603 - - - 3.4199 - 1.764 0.415 - 96.2 1 2 1 0.0051 12 0 0 0 9.84E+06 6.59E+06 - - - 4.7387 0.9992 221125_WJC_METTL3_EV_vs_WT_F09.13998.13998.4 1.95E-07 14/114 R.SRFEYPPPPVSLGSSSHTAR.L sp|Q9H1B7|I2BPL_HUMAN 1 2171.076 1.71 132642 13998 4 2171.085161 543.7763 Probable E3 ubiquitin-protein ligase IRF2BPL OS=Homo sapiens OX=9606 GN=IRF2BPL PE=1 SV=1 8.49 2651.3 - 183404 - - - 4.2352 - 2.618 0.53 - 121.5 1 2 1 0.0092 20 0 0 0 5.51E+06 3.22E+06 - - - 4.1583 1 221125_WJC_METTL3_EV_vs_WT_F09.14006.14006.3 2.22E-13 24/84 K.DHTPSQELALTQSVGGDSSADR[166.11].L "sp|Q86U44|MTA70_HUMAN,tr|H0YFV6|H0YFV6_HUMAN" 2 2280.0494 0.08 132648 14006 3 2280.049263 761.0237 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 4.22 2652.4 - 615764 - - - -0.0456 - 4.599 0.685 - 623.4 1 2 0 -0.0001 22 0 0 0 2.48E+06 3.30E+07 - - - 9.7946 0.9996 221125_WJC_METTL3_EV_vs_WT_F09.14007.14007.4 0.000186 8/162 R.GQGPSAEAHEGAPDPMPAALHPEEVAAR[166.11].L sp|Q9HCJ3|RAVR2_HUMAN 1 2801.3067 1.96 132649 14007 4 2801.314819 701.3339 Ribonucleoprotein PTB-binding 2 OS=Homo sapiens OX=9606 GN=RAVER2 PE=1 SV=2 4.56 2652.5 - 98798.4 - - - 2.9122 - 1.77 0.412 - 26.9 1 2 0 0.0082 28 0 0 0 2.65E+07 1.35E+07 - - - 2.9871 0.9999 221125_WJC_METTL3_EV_vs_WT_F09.14014.14014.4 7.77E-07 15/162 R.GQGPSAEAHEGAPDPMPAALHPEEVAAR.L sp|Q9HCJ3|RAVR2_HUMAN 1 2791.2984 1.96 132653 14014 4 2791.304597 698.8319 Ribonucleoprotein PTB-binding 2 OS=Homo sapiens OX=9606 GN=RAVER2 PE=1 SV=2 4.56 2653.5 - 277965 - - - 2.2233 - 2.138 0.531 - 58.7 1 2 0 0.0062 28 0 0 0 2.65E+07 1.35E+07 - - - 4.082 0.9999 221125_WJC_METTL3_EV_vs_WT_F09.14017.14017.3 6.62E-06 Jun-88 R.RPSPSSQSSSLLTESEQC[160.03]SLDGK.K sp|Q5D1E8|ZC12A_HUMAN 1 2479.1497 3.9 132656 14017 3 2479.154814 827.3905 Endoribonuclease ZC3H12A OS=Homo sapiens OX=9606 GN=ZC3H12A PE=1 SV=1 4.68 2653.9 - 45798.9 - - - 2.0785 - 1.624 0.592 - 34.3 1 2 0 0.0052 23 0 0 0 5.32E+05 1.36E+05 - - - 6.2763 0.9962 221125_WJC_METTL3_EV_vs_WT_F09.14024.14024.3 0.0224 5/104 K.TSLGPGGSYQISEHAPEASQPAENISK.D "sp|Q9NQ31|AKIP1_HUMAN,tr|E9PPN7|E9PPN7_HUMAN" 2 2754.3097 4.15 132661 14024 3 2754.321422 919.1105 A-kinase-interacting protein 1 OS=Homo sapiens OX=9606 GN=AKIP1 PE=1 SV=2 4.75 2654.8 - 88094.9 - - - 4.2679 - 1.324 0.434 - 15.6 1 2 0 0.0118 27 0 0 0 1.22E+06 2.95E+05 - - - 4.0211 0.9873 221125_WJC_METTL3_EV_vs_WT_F09.14031.14031.3 0.0115 Jul-88 R.QSSLSC[160.03]SPIGDSTQVSNGGLQQK.T "sp|Q2KHR3|QSER1_HUMAN,tr|A0A3B3IRW6|A0A3B3IRW6_HUMAN" 2 2377.118 2.5 132666 14031 3 2377.129125 793.3799 Glutamine and serine-rich protein 1 OS=Homo sapiens OX=9606 GN=QSER1 PE=1 SV=3 5.83 2655.8 - 85589.6 - - - 4.6939 - 1.56 0.337 - 34 1 2 0 0.0112 23 0 0 0 6.07E+06 2.42E+06 - - - 3.3373 0.9999 221125_WJC_METTL3_EV_vs_WT_F09.14035.14035.4 0.000153 7/120 K.DFETLYNDC[160.03]TNASSR[166.11]PGR[166.11]PPK[136.11].R sp|Q9UI36|DACH1_HUMAN 1 2452.1436 2.22 132667 14035 4 2452.144367 614.0432 Dachshund homolog 1 OS=Homo sapiens OX=9606 GN=DACH1 PE=1 SV=4 6.11 2656.4 - 100045 - - - 0.3283 - 1.541 0.482 - 29.6 1 2 0 0.0008 21 0 0 0 6.75E+06 3.03E+06 - - - 3.5641 0.952 221125_WJC_METTL3_EV_vs_WT_F09.14036.14036.3 0.0419 Mar-88 R.QSSLSC[160.03]SPIGDSTQVSNGGLQQK[136.11].T "sp|Q2KHR3|QSER1_HUMAN,tr|A0A3B3IRW6|A0A3B3IRW6_HUMAN" 2 2385.1322 2.5 132668 14036 3 2385.133065 796.0513 Glutamine and serine-rich protein 1 OS=Homo sapiens OX=9606 GN=QSER1 PE=1 SV=3 5.83 2656.5 - 49853.8 - - - 0.3765 - 0.693 0.287 - 4.9 1 2 0 0.0009 23 0 0 0 6.07E+06 2.42E+06 - - - 0.8792 1 221125_WJC_METTL3_EV_vs_WT_F09.14037.14037.4 6.30E-06 14/120 K.DFETLYNDC[160.03]TNASSRPGRPPK.R sp|Q9UI36|DACH1_HUMAN 1 2424.1128 2.1 132669 14037 4 2424.118475 607.0355 Dachshund homolog 1 OS=Homo sapiens OX=9606 GN=DACH1 PE=1 SV=4 6.11 2656.7 - 152138 - - - 2.332 - 2.71 0.631 - 117.2 1 2 0 0.0057 21 0 0 0 6.76E+06 3.22E+06 - - - 5.0463 1 221125_WJC_METTL3_EV_vs_WT_F09.14038.14038.2 1.67E-10 14/34 P.SQELALTQSVGGDSSADR[166.11].L "sp|Q86U44|MTA70_HUMAN,tr|H0YFV6|H0YFV6_HUMAN" 2 1829.8631 0.001 132670 14038 2 1829.867944 915.9388 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 4.03 2656.8 - 119979 - - - 2.6641 - 3.163 0.66 - 558.8 1 1 0 0.0049 18 0 0 0 0.00E+00 9.08E+06 - - - 6.7453 0.9837 221125_WJC_METTL3_EV_vs_WT_F09.14044.14044.4 0.0459 5/114 R.SR[166.11]FEYPPPPVSLGSSSHTAR[166.11].L sp|Q9H1B7|I2BPL_HUMAN 1 2191.0925 1.8 132674 14044 4 2191.09462 548.7804 Probable E3 ubiquitin-protein ligase IRF2BPL OS=Homo sapiens OX=9606 GN=IRF2BPL PE=1 SV=1 8.49 2657.6 - 39116 - - - 0.9648 - 1.158 0.296 - 9 3 2 1 0.0021 20 0 0 0 5.44E+06 3.02E+06 - - - 1.4872 0.9939 221125_WJC_METTL3_EV_vs_WT_F09.14049.14049.2 0.00041 18-Nov K.YEELQITAGR.H "sp|P04264|K2C1_HUMAN,sp|P04259|K2C6B_HUMAN" 2 1178.5932 999 132676 14049 2 1178.599007 590.3039 "Keratin, type II cytoskeletal 1 OS=Homo sapiens OX=9606 GN=KRT1 PE=1 SV=6" 4.53 2658.3 - 475255 - - - 4.9678 - 2.172 0.314 - 522.5 1 2 0 0.0059 10 0 0 0 1.21E+07 0.00E+00 - - - 3.5234 0.9998 221125_WJC_METTL3_EV_vs_WT_F09.14053.14053.3 0.000131 Sep-92 K.QSATNLESEEDSEAPVDSTLNNNR.N "sp|Q2KHR3|QSER1_HUMAN,tr|A0A3B3IRW6|A0A3B3IRW6_HUMAN" 2 2619.1532 2.84 132679 14053 3 2619.161455 874.0584 Glutamine and serine-rich protein 1 OS=Homo sapiens OX=9606 GN=QSER1 PE=1 SV=3 3.77 2658.8 - 118038 - - - 3.1419 - 1.888 0.524 - 39.9 1 2 0 0.0082 24 0 0 0 3.99E+06 1.41E+06 - - - 5.8559 1 221125_WJC_METTL3_EV_vs_WT_F09.14057.14057.4 1.07E-06 19/114 K.R[166.11]GLLQDDAHPTLVTYADHSK[136.11].L "sp|Q86U44|MTA70_HUMAN,tr|F5H6D8|F5H6D8_HUMAN,tr|H0YFV6|H0YFV6_HUMAN,tr|B4DTN4|B4DTN4_HUMAN" 4 2254.1461 0.08 132682 14057 4 2254.148142 564.5438 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 5.99 2659.3 - 828645 - - - 0.8992 - 3.713 0.502 - 307.8 1 2 0 0.002 20 0 0 0 2.28E+06 2.97E+07 - - - 4.0334 0.9852 221125_WJC_METTL3_EV_vs_WT_F09.14061.14061.4 0.102 6/120 K.SQSKEPERPLPPLGPVAVDPK.G "sp|Q8WUR7|CO040_HUMAN,tr|H3BMR1|H3BMR1_HUMAN,tr|H0Y996|H0Y996_HUMAN" 3 2240.2165 1.03 132685 14061 4 2240.224908 561.0614 UPF0235 protein C15orf40 OS=Homo sapiens OX=9606 GN=C15orf40 PE=1 SV=2 5.9 2659.8 - 83477.3 - - - 3.7612 - 1.087 0.34 - 18.2 1 2 1 0.0084 21 0 0 0 4.03E+06 3.91E+06 - - - 2.2106 0.9999 221125_WJC_METTL3_EV_vs_WT_F09.14072.14072.3 1.32E-08 13/64 R.REEMEQLFHDDQGGVTR.W "sp|Q15643|TRIPB_HUMAN,tr|H0YJ97|H0YJ97_HUMAN" 2 2045.9225 1.2 132692 14072 3 2045.930301 682.9814 Thyroid receptor-interacting protein 11 OS=Homo sapiens OX=9606 GN=TRIP11 PE=1 SV=3 4.5 2661.5 - 72949.3 - - - 3.812 - 2.861 0.636 - 239 1 2 0 0.0078 17 0 0 0 9.29E+06 7.71E+06 - - - 8.2842 1 221125_WJC_METTL3_EV_vs_WT_F09.14073.14073.3 5.41E-05 Sep-64 R.R[166.11]EEMEQLFHDDQGGVTR[166.11].W "sp|Q15643|TRIPB_HUMAN,tr|H0YJ97|H0YJ97_HUMAN" 2 2065.939 1.2 132693 14073 3 2065.937034 689.6536 Thyroid receptor-interacting protein 11 OS=Homo sapiens OX=9606 GN=TRIP11 PE=1 SV=3 4.5 2661.6 - 66671.1 - - - -0.972 - 2.164 0.546 - 70.7 1 2 0 -0.002 17 0 0 0 9.29E+06 7.71E+06 - - - 6.577 1 221125_WJC_METTL3_EV_vs_WT_F09.14077.14077.4 7.37E-06 Dec-96 R.REEMEQLFHDDQGGVTR.W "sp|Q15643|TRIPB_HUMAN,tr|H0YJ97|H0YJ97_HUMAN" 2 2045.9225 1.3 132695 14077 4 2045.927173 512.4879 Thyroid receptor-interacting protein 11 OS=Homo sapiens OX=9606 GN=TRIP11 PE=1 SV=3 4.5 2662.2 - 82210.6 - - - 2.2831 - 2.384 0.54 - 143.2 1 2 0 0.0047 17 0 0 0 7.72E+06 5.93E+06 - - - 4.2265 0.9665 221125_WJC_METTL3_EV_vs_WT_F09.14079.14079.3 1.26E-05 Aug-76 R.SQSC[160.03]GPQPSWGASC[160.03]PELRPH.V sp|Q5T749|KPRP_HUMAN 1 2236.9742 122.24 132696 14079 3 2236.983497 746.6653 Keratinocyte proline-rich protein OS=Homo sapiens OX=9606 GN=KPRP PE=1 SV=1 6.46 2662.4 - 62389.7 - - - 4.1471 - 1.836 0.56 - 61.1 1 1 0 0.0093 20 0 0 0 4.27E+06 3.49E+04 - - - 6.2549 1 221125_WJC_METTL3_EV_vs_WT_F09.14089.14089.3 3.01E-05 Nov-56 R.STSHK[136.11]PDEIYGMIER[166.11].L sp|Q86U44|MTA70_HUMAN 1 1779.8581 0.02 132702 14089 3 1779.860058 594.2933 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 5.42 2663.9 - 274277 - - - 1.1259 - 2.178 0.499 - 163.6 1 2 0 0.002 15 0 0 0 4.04E+05 1.66E+07 - - - 6.1339 0.9972 221125_WJC_METTL3_EV_vs_WT_F09.14097.14097.4 0.000486 6/120 K.SQSK[136.11]EPER[166.11]PLPPLGPVAVDPK[136.11].G "sp|Q8WUR7|CO040_HUMAN,tr|H3BMR1|H3BMR1_HUMAN,tr|H0Y996|H0Y996_HUMAN" 3 2266.2532 1.03 132708 14097 4 2266.259892 567.5706 UPF0235 protein C15orf40 OS=Homo sapiens OX=9606 GN=C15orf40 PE=1 SV=2 5.9 2665 - 85564.1 - - - 2.9741 - 1.316 0.394 - 19.1 1 2 1 0.0067 21 0 0 0 4.03E+06 3.91E+06 - - - 2.7443 1 221125_WJC_METTL3_EV_vs_WT_F09.14108.14108.4 4.36E-10 19/96 R.R[166.11]EEMEQLFHDDQGGVTR[166.11].W "sp|Q15643|TRIPB_HUMAN,tr|H0YJ97|H0YJ97_HUMAN" 2 2065.939 1.3 132714 14108 4 2065.941596 517.492 Thyroid receptor-interacting protein 11 OS=Homo sapiens OX=9606 GN=TRIP11 PE=1 SV=3 4.5 2666.5 - 229824 - - - 1.2362 - 3.522 0.653 - 379.9 1 2 0 0.0026 17 0 0 0 7.73E+06 5.93E+06 - - - 5.3461 0.9994 221125_WJC_METTL3_EV_vs_WT_F09.14117.14117.3 0.00576 Sep-40 R.LLASTLVHSVK.K "sp|Q9NYF8|BCLF1_HUMAN,tr|E9PKI6|E9PKI6_HUMAN,tr|A0A1W2PQ43|A0A1W2PQ43_HUMAN,tr|E9PK91|E9PK91_HUMAN,tr|E9PJA7|E9PJA7_HUMAN,tr|E9PK09|E9PK09_HUMAN,tr|E9PQN2|E9PQN2_HUMAN" 7 1166.7023 2.13 132720 14117 3 1166.703845 389.908 Bcl-2-associated transcription factor 1 OS=Homo sapiens OX=9606 GN=BCLAF1 PE=1 SV=2 8.76 2667.7 - 130639 - - - 1.3165 - 2.088 0.294 - 72.2 1 2 0 0.0015 11 0 0 0 7.91E+06 3.71E+06 - - - 3.9088 0.9999 221125_WJC_METTL3_EV_vs_WT_F09.14120.14120.3 8.53E-06 8/108 R.GQGPSAEAHEGAPDPMPAALHPEEVAAR.L sp|Q9HCJ3|RAVR2_HUMAN 1 2791.2984 5.94 132723 14120 3 2791.306099 931.4401 Ribonucleoprotein PTB-binding 2 OS=Homo sapiens OX=9606 GN=RAVER2 PE=1 SV=2 4.56 2668.1 - 47309.2 - - - 2.7614 - 1.947 0.601 - 41.5 1 2 0 0.0077 28 0 0 0 1.28E+06 2.15E+05 - - - 6.7713 0.9993 221125_WJC_METTL3_EV_vs_WT_F09.14129.14129.3 3.65E-06 Aug-52 K.K[136.11]GPGEVAGTVTGQK[136.11].R "sp|Q86U44|MTA70_HUMAN,tr|F5H6D8|F5H6D8_HUMAN,tr|H0YFV6|H0YFV6_HUMAN,tr|B4DTN4|B4DTN4_HUMAN" 4 1343.738 0.01 132726 14129 3 1343.742775 448.9199 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 8.59 2669.5 - 144081 - - - 3.5691 - 1.873 0.435 - 95.7 1 2 0 0.0048 14 0 0 0 2.81E+04 3.46E+06 - - - 5.0562 0.9646 221125_WJC_METTL3_EV_vs_WT_F09.14141.14141.4 0.000164 10/150 R.NPEAALSPTFR[166.11]SDSPVPTAPTSGGPK[136.11].P "sp|Q86U44|MTA70_HUMAN,tr|B4E349|B4E349_HUMAN,tr|F5H6D8|F5H6D8_HUMAN,tr|B4DTN4|B4DTN4_HUMAN" 4 2598.3045 0.02 132734 14141 4 2598.310799 650.5834 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 6.07 2671.2 - 79791.2 - - - 2.4374 - 1.928 0.511 - 59 1 1 1 0.0063 26 0 0 0 4.49E+04 2.28E+06 - - - 3.8791 0.9999 221125_WJC_METTL3_EV_vs_WT_F09.14155.14155.3 2.35E-05 Oct-72 K.NTNDANSC[160.03]QIIIPQNQVNR.K "sp|P31150|GDIA_HUMAN,sp|P50395|GDIB_HUMAN,tr|Q5SX91|Q5SX91_HUMAN" 3 2198.0498 3.34 132742 14155 3 2198.053185 733.6906 Rab GDP dissociation inhibitor alpha OS=Homo sapiens OX=9606 GN=GDI1 PE=1 SV=2 5.83 2673.1 - 151588 - - - 1.5273 - 1.83 0.477 - 66.8 1 2 0 0.0034 19 0 0 0 3.84E+06 1.15E+06 - - - 5.3418 0.8158 221125_WJC_METTL3_EV_vs_WT_F09.14163.14163.3 0.76 Feb-76 R.QNQFYDTQVIKQENESGYER.R "sp|Q9BUJ2|HNRL1_HUMAN,tr|M0R0K8|M0R0K8_HUMAN,tr|M0QYZ0|M0QYZ0_HUMAN,tr|A0A0A0MRA5|A0A0A0MRA5_HUMAN,tr|M0QZV6|M0QZV6_HUMAN,tr|B7Z4B8|B7Z4B8_HUMAN,tr|M0R203|M0R203_HUMAN" 7 2475.1302 2.12 132748 14163 3 2475.131047 826.0507 Heterogeneous nuclear ribonucleoprotein U-like protein 1 OS=Homo sapiens OX=9606 GN=HNRNPUL1 PE=1 SV=2 4.41 2674.2 - 40647.5 - - - 0.3236 - 0.726 0.316 - 2.7 7 2 1 0.0008 20 0 0 0 5.53E+05 2.61E+05 - - - 0.8949 1 221125_WJC_METTL3_EV_vs_WT_F09.14173.14173.4 0.00127 8/156 K.SIAAC[160.03]HNVGLLAHDGQVNEDGQPDLGK[136.11].A sp|Q96BR5|COA7_HUMAN 1 2822.3497 0.59 132754 14173 4 2822.34984 706.5947 Cytochrome c oxidase assembly factor 7 OS=Homo sapiens OX=9606 GN=COA7 PE=1 SV=2 4.63 2675.6 - 95345.6 - - - 0.0478 - 1.467 0.526 - 26.4 1 2 0 0.0001 27 0 0 0 2.23E+06 3.74E+06 - - - 3.9242 0.9985 221125_WJC_METTL3_EV_vs_WT_F09.14180.14180.2 0.0104 18-Jun R.YSGSYNDYLR.A sp|Q96PK6|RBM14_HUMAN 1 1236.5411 2.45 132759 14180 2 1236.542921 619.2778 RNA-binding protein 14 OS=Homo sapiens OX=9606 GN=RBM14 PE=1 SV=2 5.83 2676.6 - 52742.3 - - - 1.4589 - 1.23 0.383 - 77.9 1 2 0 0.0018 10 0 0 0 1.17E+06 4.75E+05 - - - 2.4471 0.9319 221125_WJC_METTL3_EV_vs_WT_F09.14182.14182.2 0.0052 22-Jul W.ELISNASDALDK.L "sp|Q58FF8|H90B2_HUMAN,sp|P08238|HS90B_HUMAN,sp|Q58FF6|H90B4_HUMAN,sp|Q58FF7|H90B3_HUMAN,sp|P14625|ENPL_HUMAN,tr|A0A7P0T917|A0A7P0T917_HUMAN,tr|A0A7P0Z405|A0A7P0Z405_HUMAN,tr|A0A7P0T823|A0A7P0T823_HUMAN,tr|A0A7P0TAE1|A0A7P0TAE1_HUMAN,tr|H0YIV0|H0YIV0_HUMAN,tr|A0A7P0T8R3|A0A7P0T8R3_HUMAN,tr|A0A7P0T885|A0A7P0T885_HUMAN,tr|A0A7P0TAY2|A0A7P0TAY2_HUMAN,tr|A0A087WT78|A0A087WT78_HUMAN,tr|F8W026|F8W026_HUMAN,tr|A0A7P0TBC2|A0A7P0TBC2_HUMAN,tr|A0A7P0TAT8|A0A7P0TAT8_HUMAN" 17 1274.6354 15.27 132760 14182 2 1274.638744 638.325 Putative heat shock protein HSP 90-beta 2 OS=Homo sapiens OX=9606 GN=HSP90AB2P PE=1 SV=2 4.03 2676.9 - 99294.3 - - - 2.6149 - 1.878 0.367 - 134.4 1 1 0 0.0033 12 0 0 0 3.90E+06 2.55E+05 - - - 3.4088 1 221125_WJC_METTL3_EV_vs_WT_F09.14200.14200.2 6.64E-12 Nov-38 R.FSSC[160.03]GGGGGSFGAGGGFGSR.S sp|P04264|K2C1_HUMAN 1 1764.7274 999 132769 14200 2 1764.73225 883.371 "Keratin, type II cytoskeletal 1 OS=Homo sapiens OX=9606 GN=KRT1 PE=1 SV=6" 8.25 2679.5 - 78707 - - - 2.7307 - 2.294 0.782 - 235.5 1 2 0 0.0048 20 0 0 0 4.03E+06 0.00E+00 - - - 6.8567 0.9767 221125_WJC_METTL3_EV_vs_WT_F09.14208.14208.3 0.0298 Aug-52 R.KKDEISVDSLDFNK.K "sp|P63151|2ABA_HUMAN,tr|A0A590UJJ1|A0A590UJJ1_HUMAN,tr|E5RFR9|E5RFR9_HUMAN,tr|A0A590UJY3|A0A590UJY3_HUMAN" 4 1636.8308 0.49 132773 14208 3 1636.834925 546.6175 Serine\threonine-protein phosphatase 2A 55 kDa regulatory subunit B alpha isoform OS=Homo sapiens OX=9606 GN=PPP2R2A PE=1 SV=1 4.68 2680.7 - 65307.3 - - - 2.5103 - 1.376 0.312 - 80.8 1 2 1 0.0041 14 0 0 0 2.42E+06 4.97E+06 - - - 2.8656 0.9636 221125_WJC_METTL3_EV_vs_WT_F09.14210.14210.4 0.038 Aug-72 K.ELHINLIPNK[136.11]QDR[166.11].T "sp|P07900|HS90A_HUMAN,tr|G3V2J8|G3V2J8_HUMAN" 2 1606.891 0.63 132775 14210 4 1606.892713 402.73 Heat shock protein HSP 90-alpha OS=Homo sapiens OX=9606 GN=HSP90AA1 PE=1 SV=5 6.85 2680.9 - 120694 - - - 1.0604 - 1.515 0.208 - 37.7 1 2 1 0.0017 13 0 0 0 2.62E+06 4.17E+06 - - - 1.19 0.9996 221125_WJC_METTL3_EV_vs_WT_F09.14223.14223.3 0.0111 Jun-96 K.VQERPPSASSSSDMSLSEPPQPLAR.K sp|Q5VT06|CE350_HUMAN 1 2652.2813 3.27 132781 14223 3 2652.288831 885.1011 Centrosome-associated protein 350 OS=Homo sapiens OX=9606 GN=CEP350 PE=1 SV=1 4.68 2682.8 - 47749.4 - - - 2.8229 - 1.731 0.48 - 19.4 1 2 0 0.0075 25 0 0 0 1.53E+06 4.66E+05 - - - 5.1518 0.998 221125_WJC_METTL3_EV_vs_WT_F09.14229.14229.2 0.467 16-Jul K.VGLQVVAVK.A "sp|P10809|CH60_HUMAN,tr|A0A7I2V2X6|A0A7I2V2X6_HUMAN,tr|A0A7I2YQK6|A0A7I2YQK6_HUMAN,tr|A0A7I2V599|A0A7I2V599_HUMAN,tr|A0A7I2V5M1|A0A7I2V5M1_HUMAN" 5 911.5804 1.24 132785 14229 2 911.579996 456.7975 "60 kDa heat shock protein, mitochondrial OS=Homo sapiens OX=9606 GN=HSPD1 PE=1 SV=2" 8.72 2683.7 - 120549 - - - -0.4465 - 1.447 0.231 - 96.6 1 2 0 -0.0004 9 0 0 0 8.67E+06 7.02E+06 - - - 1.816 0.9969 221125_WJC_METTL3_EV_vs_WT_F09.14233.14233.3 0.00257 May-96 K.GKTPVFQSSQTSSVSSVNPSVTTIK.T sp|Q8TBA6|GOGA5_HUMAN 1 2565.3286 1.89 132786 14233 3 2565.327854 856.1168 Golgin subfamily A member 5 OS=Homo sapiens OX=9606 GN=GOLGA5 PE=1 SV=3 10 2684.3 - 114982 - - - -0.2955 - 1.287 0.402 - 19.9 1 2 1 -0.0008 25 0 0 0 1.46E+07 7.70E+06 - - - 3.6022 0.9966 221125_WJC_METTL3_EV_vs_WT_F09.14234.14234.3 0.00859 May-96 K.GK[136.11]TPVFQSSQTSSVSSVNPSVTTIK[136.11].T sp|Q8TBA6|GOGA5_HUMAN 1 2581.357 1.89 132787 14234 3 2581.361495 861.4596 Golgin subfamily A member 5 OS=Homo sapiens OX=9606 GN=GOLGA5 PE=1 SV=3 10 2684.4 - 77035.8 - - - 1.7367 - 1.192 0.445 - 13.8 1 2 1 0.0045 25 0 0 0 1.46E+07 7.70E+06 - - - 3.9041 0.9976 221125_WJC_METTL3_EV_vs_WT_F09.14241.14241.4 0.0726 8/102 K.LLNTVEETTKDVSGLHSK.L "sp|P52732|KIF11_HUMAN,tr|A0A7I2YQY4|A0A7I2YQY4_HUMAN,tr|A0A7I2V3A9|A0A7I2V3A9_HUMAN" 3 1970.032 2.85 132791 14241 4 1970.032767 493.5153 Kinesin-like protein KIF11 OS=Homo sapiens OX=9606 GN=KIF11 PE=1 SV=2 5.45 2685.4 - 240352 - - - 0.3711 - 1.67 0.33 - 19 1 2 1 0.0007 18 0 0 0 4.45E+06 1.56E+06 - - - 2.2738 0.8231 221125_WJC_METTL3_EV_vs_WT_F09.14251.14251.4 1.84 6/120 R.RLEPYMAPSMVTSVVC[160.03]SSEGR[166.11].G "sp|Q38SD2|LRRK1_HUMAN,tr|H0YEW1|H0YEW1_HUMAN" 2 2365.1104 - 132796 14251 4 2365.109218 592.2849 Leucine-rich repeat serine\threonine-protein kinase 1 OS=Homo sapiens OX=9606 GN=LRRK1 PE=1 SV=3 6.14 2686.8 - 226129 - - - -0.4968 - 1.01 0.11 - 20.4 1 2 0 -0.0012 21 0 0 0 - - - - - 0.1864 1 221125_WJC_METTL3_EV_vs_WT_F09.14281.14281.4 3.42E-07 21/114 K.R[166.11]GLLQDDAHPTLVTYADHSK[136.11].L "sp|Q86U44|MTA70_HUMAN,tr|F5H6D8|F5H6D8_HUMAN,tr|H0YFV6|H0YFV6_HUMAN,tr|B4DTN4|B4DTN4_HUMAN" 4 2254.1461 0.03 132813 14281 4 2254.141629 564.5438 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 5.99 2690.9 - 751137 - - - -1.9901 - 3.841 0.588 - 472 1 2 0 -0.0045 20 0 0 0 1.15E+06 4.51E+07 - - - 4.7926 1 221125_WJC_METTL3_EV_vs_WT_F09.14295.14295.3 1.86E-06 Aug-88 K.KGTDVLPSQIDQQNSVSPDTPVR.K sp|Q5T3J3|LRIF1_HUMAN 1 2480.2507 3.24 132821 14295 3 2480.247996 827.7575 Ligand-dependent nuclear receptor-interacting factor 1 OS=Homo sapiens OX=9606 GN=LRIF1 PE=1 SV=1 4.43 2692.8 - 36537.4 - - - -1.0886 - 1.896 0.54 - 51.9 1 2 0 -0.0027 23 0 0 0 5.72E+06 1.76E+06 - - - 6.0605 0.9996 221125_WJC_METTL3_EV_vs_WT_F09.14310.14310.3 0.000637 Aug-56 R.STSHK[136.11]PDEIYGMIER[166.11].L sp|Q86U44|MTA70_HUMAN 1 1779.8581 0.01 132832 14310 3 1779.860456 594.2933 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 5.42 2694.7 - 230903 - - - 1.3495 - 1.675 0.398 - 70.3 1 2 0 0.0024 15 0 0 0 5.25E+04 6.90E+06 - - - 4.3226 0.9996 221125_WJC_METTL3_EV_vs_WT_F09.14311.14311.3 0.00037 Aug-40 K.IWHHTFYNELR[166.11].V "sp|Q6S8J3|POTEE_HUMAN,sp|P63261|ACTG_HUMAN,sp|P68133|ACTS_HUMAN,sp|Q9BYX7|ACTBM_HUMAN,sp|P68032|ACTC_HUMAN,sp|P60709|ACTB_HUMAN,sp|A5A3E0|POTEF_HUMAN,sp|P0CG38|POTEI_HUMAN,sp|P0CG39|POTEJ_HUMAN,tr|A0A804GS07|A0A804GS07_HUMAN,tr|I3L3I0|I3L3I0_HUMAN,tr|G5E9R0|G5E9R0_HUMAN,tr|E7EVS6|E7EVS6_HUMAN,tr|A0A6Q8PFE4|A0A6Q8PFE4_HUMAN,tr|J3KT65|J3KT65_HUMAN,tr|I3L3R2|I3L3R2_HUMAN,tr|K7EM38|K7EM38_HUMAN,tr|A0A6Q8PH58|A0A6Q8PH58_HUMAN,tr|I3L1U9|I3L1U9_HUMAN,tr|A0A804HKV3|A0A804HKV3_HUMAN,tr|A0A2R8Y793|A0A2R8Y793_HUMAN,tr|I3L4N8|I3L4N8_HUMAN,tr|C9JUM1|C9JUM1_HUMAN,tr|C9JZR7|C9JZR7_HUMAN,tr|A0A2R8YGF8|A0A2R8YGF8_HUMAN,tr|A6NL76|A6NL76_HUMAN" 26 1524.7502 0.85 132833 14311 3 1524.754345 509.2573 POTE ankyrin domain family member E OS=Homo sapiens OX=9606 GN=POTEE PE=2 SV=3 6.92 2694.9 - 103619 - - - 2.75 - 1.717 0.45 - 86.4 1 2 0 0.0042 11 0 0 0 5.63E+06 6.58E+06 - - - 5.0916 1 221125_WJC_METTL3_EV_vs_WT_F09.14316.14316.3 2.05E-12 17/84 K.DHTPSQELALTQSVGGDSSADR.L "sp|Q86U44|MTA70_HUMAN,tr|H0YFV6|H0YFV6_HUMAN" 2 2270.0411 0.03 132835 14316 3 2270.034567 757.6876 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 4.22 2695.7 - 157772 - - - -2.8766 - 3.482 0.656 - 317.6 1 2 0 -0.0065 22 0 0 0 3.20E+09 1.01E+11 - - - 8.8098 1 221125_WJC_METTL3_EV_vs_WT_F09.14317.14317.3 1.48E-06 Sep-88 K.K[136.11]GTDVLPSQIDQQNSVSPDTPVR[166.11].K sp|Q5T3J3|LRIF1_HUMAN 1 2498.2732 3.24 132836 14317 3 2498.271924 833.765 Ligand-dependent nuclear receptor-interacting factor 1 OS=Homo sapiens OX=9606 GN=LRIF1 PE=1 SV=1 4.43 2695.8 - 57409.4 - - - -0.4971 - 2.226 0.62 - 79.2 1 2 0 -0.0012 23 0 0 0 5.72E+06 1.76E+06 - - - 7.3293 0.9964 221125_WJC_METTL3_EV_vs_WT_F09.14324.14324.3 0.156 May-40 K.IWHHTFYNELR.V "sp|Q6S8J3|POTEE_HUMAN,sp|P63261|ACTG_HUMAN,sp|P68133|ACTS_HUMAN,sp|Q9BYX7|ACTBM_HUMAN,sp|P68032|ACTC_HUMAN,sp|P60709|ACTB_HUMAN,sp|A5A3E0|POTEF_HUMAN,sp|P0CG38|POTEI_HUMAN,sp|P0CG39|POTEJ_HUMAN,tr|A0A804GS07|A0A804GS07_HUMAN,tr|I3L3I0|I3L3I0_HUMAN,tr|G5E9R0|G5E9R0_HUMAN,tr|E7EVS6|E7EVS6_HUMAN,tr|A0A6Q8PFE4|A0A6Q8PFE4_HUMAN,tr|J3KT65|J3KT65_HUMAN,tr|I3L3R2|I3L3R2_HUMAN,tr|K7EM38|K7EM38_HUMAN,tr|A0A6Q8PH58|A0A6Q8PH58_HUMAN,tr|I3L1U9|I3L1U9_HUMAN,tr|A0A804HKV3|A0A804HKV3_HUMAN,tr|A0A2R8Y793|A0A2R8Y793_HUMAN,tr|I3L4N8|I3L4N8_HUMAN,tr|C9JUM1|C9JUM1_HUMAN,tr|C9JZR7|C9JZR7_HUMAN,tr|A0A2R8YGF8|A0A2R8YGF8_HUMAN,tr|A6NL76|A6NL76_HUMAN" 26 1514.7419 0.85 132838 14324 3 1514.74631 505.9212 POTE ankyrin domain family member E OS=Homo sapiens OX=9606 GN=POTEE PE=2 SV=3 6.92 2696.8 - 86922.1 - - - 2.9233 - 1.375 0.347 - 35.3 1 2 0 0.0044 11 0 0 0 5.64E+06 6.66E+06 - - - 3.3122 0.9926 221125_WJC_METTL3_EV_vs_WT_F09.14331.14331.4 0.00128 9/144 R.QVAASPAVGQPLQK[136.11]EPSLHLDTPSK[136.11].F "sp|Q92547|TOPB1_HUMAN,tr|A0A2R8YD63|A0A2R8YD63_HUMAN" 2 2613.4097 1.77 132842 14331 4 2613.399841 654.3597 DNA topoisomerase 2-binding protein 1 OS=Homo sapiens OX=9606 GN=TOPBP1 PE=1 SV=3 6.75 2697.7 - 105505 - - - -3.7786 - 1.928 0.356 - 31.2 1 2 1 -0.0099 25 0 0 0 2.16E+06 1.22E+06 - - - 2.5307 0.9998 221125_WJC_METTL3_EV_vs_WT_F09.14335.14335.4 0.000143 9/120 R.VFQSLPHENK[136.11]PLTLSNYQTNK[136.11].A "sp|P04080|CYTB_HUMAN,tr|A0A1W2PQG6|A0A1W2PQG6_HUMAN" 2 2473.2936 0.42 132844 14335 4 2473.289425 619.3307 Cystatin-B OS=Homo sapiens OX=9606 GN=CSTB PE=1 SV=2 8.48 2698.2 - 507719 - - - -1.6973 - 2.202 0.404 - 43.9 1 2 0 -0.0042 21 0 0 0 9.64E+06 2.28E+07 - - - 3.0022 0.9959 221125_WJC_METTL3_EV_vs_WT_F09.14339.14339.4 1.30E-12 26/126 K.DHTPSQELALTQSVGGDSSADR[166.11].L "sp|Q86U44|MTA70_HUMAN,tr|H0YFV6|H0YFV6_HUMAN" 2 2280.0494 0.01 132846 14339 4 2281.042666 571.0196 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 4.22 2698.7 - 825954 - - - 435.648 - 4.464 0.613 - 451 1 2 0 0.9933 22 0 0 0 4.97E+06 8.03E+08 - - - 4.7759 1 221125_WJC_METTL3_EV_vs_WT_F09.14349.14349.3 4.99E-09 18/68 K.YVHYEIDAC[160.03]MDSEAPGSK[136.11].D "sp|Q86U44|MTA70_HUMAN,tr|H0YFV6|H0YFV6_HUMAN" 2 2078.8805 0.01 132849 14349 3 2079.87195 693.9674 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 4.31 2700 - 865884 - - - 476.9192 - 3.511 0.693 - 354.6 1 2 0 0.9915 18 0 0 0 2.80E+05 5.41E+07 - - - 9.119 1 221125_WJC_METTL3_EV_vs_WT_F09.14366.14366.2 3.68E-12 26/42 K.DHTPSQELALTQSVGGDSSADR.L "sp|Q86U44|MTA70_HUMAN,tr|H0YFV6|H0YFV6_HUMAN" 2 2270.0411 0.02 132852 14366 2 2271.032566 1136.0278 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 4.22 2702.6 - 3.02E+06 - - - 436.7626 - 4.352 0.731 - 1103.2 1 2 0 0.9915 22 0 0 0 7.65E+07 3.18E+09 - - - 7.7445 1 221125_WJC_METTL3_EV_vs_WT_F09.14457.14457.2 3.06E-15 27/42 K.DHTPSQELALTQSVGGDSSADR[166.11].L "sp|Q86U44|MTA70_HUMAN,tr|H0YFV6|H0YFV6_HUMAN" 2 2280.0494 0.02 132864 14457 2 2280.039186 1141.032 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 4.22 2716.8 - 3.47E+06 - - - -4.4653 - 4.658 0.782 - 1480.7 1 2 0 -0.0102 22 0 0 0 7.65E+07 3.18E+09 - - - 8.5963 0.9969 221125_WJC_METTL3_EV_vs_WT_F09.14462.14462.4 2.72E-05 17/120 R.EQQAQVEK[136.11]EDFSDMVAEHAAK[136.11].Q "sp|Q13435|SF3B2_HUMAN,tr|E9PPJ0|E9PPJ0_HUMAN,tr|H0YEX5|H0YEX5_HUMAN" 3 2405.114 1.15 132865 14462 4 2405.101956 602.2858 Splicing factor 3B subunit 2 OS=Homo sapiens OX=9606 GN=SF3B2 PE=1 SV=2 4.35 2717.5 - 1.45E+06 - - - -5.0093 - 2.786 0.456 - 148.1 1 2 1 -0.012 21 0 0 0 2.19E+07 1.90E+07 - - - 3.5305 0.9994 221125_WJC_METTL3_EV_vs_WT_F09.14463.14463.4 5.80E-05 19/114 K.SAVADKHELLSLASSNHLGK.N "sp|O15372|EIF3H_HUMAN,tr|B3KS98|B3KS98_HUMAN,tr|A0A087WZK9|A0A087WZK9_HUMAN,tr|E5RJT0|E5RJT0_HUMAN" 4 2076.0964 1.93 132866 14463 4 2076.089322 520.0314 Eukaryotic translation initiation factor 3 subunit H OS=Homo sapiens OX=9606 GN=EIF3H PE=1 SV=1 6.66 2717.6 - 870412 - - - -3.3934 - 3.412 0.481 - 196.9 1 2 1 -0.007 20 0 0 0 1.10E+08 5.71E+07 - - - 3.821 0.9998 221125_WJC_METTL3_EV_vs_WT_F09.14470.14470.4 2.99E-08 17/114 K.SAVADK[136.11]HELLSLASSNHLGK[136.11].N "sp|O15372|EIF3H_HUMAN,tr|B3KS98|B3KS98_HUMAN,tr|A0A087WZK9|A0A087WZK9_HUMAN,tr|E5RJT0|E5RJT0_HUMAN" 4 2092.1248 1.93 132871 14470 4 2092.118445 524.0385 Eukaryotic translation initiation factor 3 subunit H OS=Homo sapiens OX=9606 GN=EIF3H PE=1 SV=1 6.66 2718.6 - 740170 - - - -3.0218 - 3.568 0.548 - 258.3 1 2 1 -0.0063 20 0 0 0 1.10E+08 5.70E+07 - - - 4.4193 1 221125_WJC_METTL3_EV_vs_WT_F09.14472.14472.4 4.37E-13 25/120 K.DHQTITIQEMPEK[136.11]APAGQLPR[166.11].S "sp|P25205|MCM3_HUMAN,tr|J3KQ69|J3KQ69_HUMAN,tr|A0A499FHX9|A0A499FHX9_HUMAN" 3 2377.2179 0.67 132873 14472 4 2377.212923 595.3118 DNA replication licensing factor MCM3 OS=Homo sapiens OX=9606 GN=MCM3 PE=1 SV=3 5.45 2718.8 - 764777 - - - -2.0932 - 4.346 0.632 - 415.8 1 2 1 -0.005 21 0 0 0 4.72E+06 7.01E+06 - - - 5.2113 0.9989 221125_WJC_METTL3_EV_vs_WT_F09.14478.14478.4 0.00163 11/120 R.EQQAQVEKEDFSDMVAEHAAK.Q "sp|Q13435|SF3B2_HUMAN,tr|E9PPJ0|E9PPJ0_HUMAN,tr|H0YEX5|H0YEX5_HUMAN" 3 2389.0856 1.15 132877 14478 4 2389.081155 598.2787 Splicing factor 3B subunit 2 OS=Homo sapiens OX=9606 GN=SF3B2 PE=1 SV=2 4.35 2719.6 - 1.85E+06 - - - -1.8622 - 2.095 0.379 - 70.9 1 2 1 -0.0044 21 0 0 0 2.19E+07 1.90E+07 - - - 2.7681 1 221125_WJC_METTL3_EV_vs_WT_F09.14480.14480.3 6.22E-09 14/80 R.EQQAQVEKEDFSDMVAEHAAK.Q "sp|Q13435|SF3B2_HUMAN,tr|E9PPJ0|E9PPJ0_HUMAN,tr|H0YEX5|H0YEX5_HUMAN" 3 2389.0856 1.43 132879 14480 3 2389.085921 797.3691 Splicing factor 3B subunit 2 OS=Homo sapiens OX=9606 GN=SF3B2 PE=1 SV=2 4.35 2719.9 - 488542 - - - 0.1327 - 2.741 0.658 - 240 1 2 1 0.0003 21 0 0 0 6.27E+06 4.39E+06 - - - 8.2934 0.8971 221125_WJC_METTL3_EV_vs_WT_F09.14482.14482.2 4.28 12-May K.NIFLGEK.A "sp|Q96FA3|PELI1_HUMAN,sp|Q9HAT8|PELI2_HUMAN,tr|H0YNF4|H0YNF4_HUMAN,tr|H0YK56|H0YK56_HUMAN" 4 819.4491 200.91 132881 14482 2 819.44695 410.7318 E3 ubiquitin-protein ligase pellino homolog 1 OS=Homo sapiens OX=9606 GN=PELI1 PE=1 SV=2 6 2720.1 - 253814 - - - -2.5676 - 1.195 0.057 - 60.2 3 2 0 -0.0021 7 0 0 0 1.00E+07 4.99E+04 - - - -0.1873 0.9999 221125_WJC_METTL3_EV_vs_WT_F09.14487.14487.3 7.33E-08 18/76 K.SAVADKHELLSLASSNHLGK.N "sp|O15372|EIF3H_HUMAN,tr|B3KS98|B3KS98_HUMAN,tr|A0A087WZK9|A0A087WZK9_HUMAN,tr|E5RJT0|E5RJT0_HUMAN" 4 2076.0964 1.98 132883 14487 3 2076.093403 693.0394 Eukaryotic translation initiation factor 3 subunit H OS=Homo sapiens OX=9606 GN=EIF3H PE=1 SV=1 6.66 2720.8 - 582753 - - - -1.4277 - 3.47 0.6 - 387.1 1 2 1 -0.003 20 0 0 0 1.79E+07 9.01E+06 - - - 8.2469 0.9999 221125_WJC_METTL3_EV_vs_WT_F09.14490.14490.4 0.0267 21/120 K.DHQTITIQEMPEKAPAGQLPR.S "sp|P25205|MCM3_HUMAN,tr|J3KQ69|J3KQ69_HUMAN,tr|A0A499FHX9|A0A499FHX9_HUMAN" 3 2359.1954 0.64 132886 14490 4 2359.19256 590.8061 DNA replication licensing factor MCM3 OS=Homo sapiens OX=9606 GN=MCM3 PE=1 SV=3 5.45 2721.2 - 477828 - - - -1.2161 - 3.592 0.56 - 301.6 1 2 1 -0.0029 21 0 0 0 6.40E+06 1.00E+07 - - - 4.5222 0.9997 221125_WJC_METTL3_EV_vs_WT_F09.14491.14491.3 0.000407 Nov-56 R.ADTQTYQPYNKDWIK.E sp|P84090|ERH_HUMAN 1 1869.8897 2.98 132887 14491 3 1869.889273 624.3039 Enhancer of rudimentary homolog OS=Homo sapiens OX=9606 GN=ERH PE=1 SV=1 6 2721.3 - 470542 - - - -0.2433 - 2.169 0.455 - 162.5 1 2 1 -0.0005 15 0 0 0 2.05E+07 6.86E+06 - - - 5.633 0.9999 221125_WJC_METTL3_EV_vs_WT_F09.14499.14499.4 9.37E-06 13/90 R.ETNLDSLPLVDTHSK[136.11]R[166.11].T sp|P08670|VIME_HUMAN 1 1841.9602 1.95 132893 14499 4 1841.955169 461.4973 Vimentin OS=Homo sapiens OX=9606 GN=VIM PE=1 SV=4 5.38 2722.4 - 245433 - - - -2.7373 - 2.382 0.538 - 125.4 1 2 0 -0.005 16 0 0 0 3.69E+07 1.89E+07 - - - 4.2131 1 221125_WJC_METTL3_EV_vs_WT_F09.14500.14500.4 3.17E-06 16/90 R.ETNLDSLPLVDTHSKR.T sp|P08670|VIME_HUMAN 1 1823.9377 1.82 132894 14500 4 1823.934696 456.9917 Vimentin OS=Homo sapiens OX=9606 GN=VIM PE=1 SV=4 5.38 2722.5 - 388032 - - - -1.6695 - 3.355 0.547 - 279.6 1 2 0 -0.003 16 0 0 0 3.42E+07 1.88E+07 - - - 4.4126 0.9995 221125_WJC_METTL3_EV_vs_WT_F09.14501.14501.3 5.06E-05 Nov-60 R.ETNLDSLPLVDTHSKR.T sp|P08670|VIME_HUMAN 1 1823.9377 2.09 132895 14501 3 1823.934972 608.9865 Vimentin OS=Homo sapiens OX=9606 GN=VIM PE=1 SV=4 5.38 2722.6 - 229391 - - - -1.5181 - 2.178 0.314 - 132 1 2 0 -0.0028 16 0 0 0 2.09E+07 1.00E+07 - - - 4.0373 1 221125_WJC_METTL3_EV_vs_WT_F09.14507.14507.4 6.55E-06 17/132 K.TTGTPPDSSLVTYELHSRPEQDK.F "sp|Q13561|DCTN2_HUMAN,tr|H0YI98|H0YI98_HUMAN,tr|A8K8J9|A8K8J9_HUMAN,tr|A0A7I2V5R4|A0A7I2V5R4_HUMAN,tr|F8W1I6|F8W1I6_HUMAN,tr|A0A7I2V4H4|A0A7I2V4H4_HUMAN,tr|A0A7I2V390|A0A7I2V390_HUMAN,tr|A0A7I2V4Y9|A0A7I2V4Y9_HUMAN,tr|F8VW18|F8VW18_HUMAN" 9 2557.2296 3.28 132899 14507 4 2557.224558 640.3147 Dynactin subunit 2 OS=Homo sapiens OX=9606 GN=DCTN2 PE=1 SV=4 4.75 2723.4 - 229756 - - - -1.9818 - 3.439 0.58 - 171.5 1 2 0 -0.0051 23 0 0 0 2.41E+07 7.35E+06 - - - 4.6731 0.9996 221125_WJC_METTL3_EV_vs_WT_F09.14512.14512.4 0.0105 8/114 R.LHLGSTPHNLTDANIHELAR[166.11].K "sp|Q9UN37|VPS4A_HUMAN,tr|I3L4J1|I3L4J1_HUMAN" 2 2218.1482 0.9 132902 14512 4 2218.144436 555.5443 Vacuolar protein sorting-associated protein 4A OS=Homo sapiens OX=9606 GN=VPS4A PE=1 SV=1 6.26 2724.1 - 236953 - - - -1.7118 - 1.597 0.367 - 39.9 1 2 0 -0.0038 20 0 0 0 2.36E+06 2.64E+06 - - - 2.5758 0.9996 221125_WJC_METTL3_EV_vs_WT_F09.14513.14513.4 0.0185 6/114 R.LHLGSTPHNLTDANIHELAR.K "sp|Q9UN37|VPS4A_HUMAN,tr|I3L4J1|I3L4J1_HUMAN" 2 2208.14 0.89 132903 14513 4 2208.134336 553.0423 Vacuolar protein sorting-associated protein 4A OS=Homo sapiens OX=9606 GN=VPS4A PE=1 SV=1 6.26 2724.2 - 186214 - - - -2.5483 - 1.421 0.405 - 16.6 1 2 0 -0.0056 20 0 0 0 2.36E+06 2.66E+06 - - - 2.867 0.9997 221125_WJC_METTL3_EV_vs_WT_F09.14514.14514.3 0.00256 Jul-60 R.ETNLDSLPLVDTHSK[136.11]R[166.11].T sp|P08670|VIME_HUMAN 1 1841.9602 2.09 132904 14514 3 1841.958164 614.994 Vimentin OS=Homo sapiens OX=9606 GN=VIM PE=1 SV=4 5.38 2724.4 - 182669 - - - -1.1113 - 1.515 0.417 - 54.4 1 2 0 -0.002 16 0 0 0 2.09E+07 1.00E+07 - - - 4.2545 1 221125_WJC_METTL3_EV_vs_WT_F09.14519.14519.3 1.09E-13 18/112 K.SHVEDGDIAGAPASSPEAPPAEQDPVQLK.T "sp|Q9P2E9|RRBP1_HUMAN,tr|A0A087WU26|A0A087WU26_HUMAN,tr|A0A087WVV2|A0A087WVV2_HUMAN,tr|F8W7S5|F8W7S5_HUMAN" 4 2911.3836 1.58 132907 14519 3 2911.383207 971.4685 Ribosome-binding protein 1 OS=Homo sapiens OX=9606 GN=RRBP1 PE=1 SV=5 4.01 2725 - 387926 - - - -0.1212 - 3.901 0.751 - 188.9 1 2 0 -0.0004 29 0 0 0 3.22E+07 2.04E+07 - - - 10.0445 0.9958 221125_WJC_METTL3_EV_vs_WT_F09.14520.14520.3 0.000122 Sep-56 R.STSHK[136.11]PDEIYGMIER[166.11].L sp|Q86U44|MTA70_HUMAN 1 1779.8581 0.05 132908 14520 3 1779.854105 594.2933 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 5.42 2725.2 - 138810 - - - -2.2187 - 1.856 0.24 - 104.9 1 2 0 -0.0039 15 0 0 0 1.73E+05 3.59E+06 - - - 2.8284 0.9627 221125_WJC_METTL3_EV_vs_WT_F09.14524.14524.2 0.00682 16-Aug H.LLDPDVVAR[166.11].F sp|Q86U44|MTA70_HUMAN 1 1006.5687 0.15 132910 14524 2 1006.56852 504.2916 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 4.21 2725.7 - 309700 - - - -0.1441 - 1.438 0.362 - 139.7 1 1 0 -0.0001 9 0 0 0 1.22E+06 8.29E+06 - - - 2.7656 0.9999 221125_WJC_METTL3_EV_vs_WT_F09.14525.14525.4 0.139 14/132 K.YQGDGIVEDEEETMENNEEK[136.11]K[136.11]DR[166.11].R "sp|Q9NYF8|BCLF1_HUMAN,tr|H0YF63|H0YF63_HUMAN,tr|E9PK91|E9PK91_HUMAN,tr|H0YF14|H0YF14_HUMAN" 4 2782.2086 2.27 132911 14525 4 2782.211749 696.5594 Bcl-2-associated transcription factor 1 OS=Homo sapiens OX=9606 GN=BCLAF1 PE=1 SV=2 4 2725.9 - 338201 - - - 1.1379 - 3.595 0.544 - 124.6 1 2 1 0.0032 23 0 0 0 2.09E+07 9.18E+06 - - - 4.3747 0.9999 221125_WJC_METTL3_EV_vs_WT_F09.14527.14527.4 0.000303 8/168 K.SHVEDGDIAGAPASSPEAPPAEQDPVQLK[136.11].T "sp|Q9P2E9|RRBP1_HUMAN,tr|A0A087WU26|A0A087WU26_HUMAN,tr|A0A087WVV2|A0A087WVV2_HUMAN,tr|F8W7S5|F8W7S5_HUMAN" 4 2919.3978 2.49 132913 14527 4 2919.395977 730.8567 Ribosome-binding protein 1 OS=Homo sapiens OX=9606 GN=RRBP1 PE=1 SV=5 4.01 2726.1 - 87810.6 - - - -0.6107 - 1.619 0.438 - 21.7 1 2 0 -0.0018 29 0 0 0 8.84E+06 3.55E+06 - - - 3.1863 0.9998 221125_WJC_METTL3_EV_vs_WT_F09.14531.14531.3 2.74E-05 Jul-84 K.AK[136.11]ENDENC[160.03]GPTTTVFVGNISEK[136.11].A "sp|P49756|RBM25_HUMAN,tr|E9PQU5|E9PQU5_HUMAN,tr|E9PSE8|E9PSE8_HUMAN" 3 2425.1402 1.14 132915 14531 3 2425.137905 809.3873 RNA-binding protein 25 OS=Homo sapiens OX=9606 GN=RBM25 PE=1 SV=3 4.41 2726.6 - 172302 - - - -0.9542 - 1.901 0.523 - 43.4 1 2 1 -0.0023 22 0 0 0 4.56E+06 4.00E+06 - - - 5.8933 0.9999 221125_WJC_METTL3_EV_vs_WT_F09.14532.14532.3 7.81E-07 Jun-84 K.AKENDENC[160.03]GPTTTVFVGNISEK.A "sp|P49756|RBM25_HUMAN,tr|E9PQU5|E9PQU5_HUMAN,tr|E9PSE8|E9PSE8_HUMAN" 3 2409.1118 1.23 132916 14532 3 2409.110529 804.0445 RNA-binding protein 25 OS=Homo sapiens OX=9606 GN=RBM25 PE=1 SV=3 4.41 2726.7 - 135897 - - - -0.5355 - 1.748 0.624 - 26.7 1 2 1 -0.0013 22 0 0 0 4.92E+06 4.00E+06 - - - 6.8207 0.9999 221125_WJC_METTL3_EV_vs_WT_F09.14539.14539.2 0.000132 24-Sep R.FSGSGSGTDFTLK.L "sp|A2NJV5|KV229_HUMAN,sp|A0A087WW87|KV240_HUMAN,sp|P06310|KV230_HUMAN,sp|A0A075B6S2|KVD29_HUMAN,sp|P01614|KVD40_HUMAN,sp|P01615|KVD28_HUMAN,sp|A0A075B6S6|KVD30_HUMAN,sp|A0A075B6P5|KV228_HUMAN,sp|A0A0A0MRZ7|KVD26_HUMAN" 9 1302.6092 48.59 132921 14539 2 1302.609131 652.3119 Immunoglobulin kappa variable 2-29 OS=Homo sapiens OX=9606 GN=IGKV2-29 PE=3 SV=2 5.84 2727.6 - 86799.5 - - - -0.0499 - 1.924 0.577 - 137.3 1 2 0 -0.0001 13 0 0 0 2.49E+08 5.13E+06 - - - 4.9823 0.978 221125_WJC_METTL3_EV_vs_WT_F09.14541.14541.2 0.0336 14-Apr R.AFLIEEQK.L sp|P49207|RL34_HUMAN 1 976.5229 20.68 132923 14541 2 976.524522 489.2687 60S ribosomal protein L34 OS=Homo sapiens OX=9606 GN=RPL34 PE=1 SV=3 4.53 2727.9 - 117195 - - - 1.6129 - 1.003 0.213 - 38.6 2 2 0 0.0016 8 0 0 0 3.21E+06 1.55E+05 - - - 0.4883 0.9998 221125_WJC_METTL3_EV_vs_WT_F09.14545.14545.4 0.00524 10/114 K.R[166.11]GLLQDDAHPTLVTYADHSK[136.11].L "sp|Q86U44|MTA70_HUMAN,tr|F5H6D8|F5H6D8_HUMAN,tr|H0YFV6|H0YFV6_HUMAN,tr|B4DTN4|B4DTN4_HUMAN" 4 2254.1461 0.14 132925 14545 4 2254.14348 564.5438 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 5.99 2728.5 - 220424 - - - -1.169 - 2.315 0.381 - 72.2 1 2 0 -0.0026 20 0 0 0 5.10E+05 3.59E+06 - - - 2.8221 1 221125_WJC_METTL3_EV_vs_WT_F09.14549.14549.4 6.35E-05 9/132 K.TTGTPPDSSLVTYELHSR[166.11]PEQDK[136.11].F "sp|Q13561|DCTN2_HUMAN,tr|H0YI98|H0YI98_HUMAN,tr|A8K8J9|A8K8J9_HUMAN,tr|A0A7I2V5R4|A0A7I2V5R4_HUMAN,tr|F8W1I6|F8W1I6_HUMAN,tr|A0A7I2V4H4|A0A7I2V4H4_HUMAN,tr|A0A7I2V390|A0A7I2V390_HUMAN,tr|A0A7I2V4Y9|A0A7I2V4Y9_HUMAN,tr|F8VW18|F8VW18_HUMAN" 9 2575.2521 3.27 132927 14549 4 2575.251976 644.8203 Dynactin subunit 2 OS=Homo sapiens OX=9606 GN=DCTN2 PE=1 SV=4 4.75 2729 - 182607 - - - -0.0466 - 2.169 0.479 - 50.2 1 2 0 -0.0001 23 0 0 0 2.40E+07 7.35E+06 - - - 3.646 1 221125_WJC_METTL3_EV_vs_WT_F09.14551.14551.4 2.76E-05 10/114 K.VAHPIR[166.11]PK[136.11]PPSATSIPAILK[136.11].A "sp|Q9UMS4|PRP19_HUMAN,tr|F5GY56|F5GY56_HUMAN" 2 2118.2888 1.41 132929 14551 4 2118.289959 530.5795 Pre-mRNA-processing factor 19 OS=Homo sapiens OX=9606 GN=PRPF19 PE=1 SV=1 11.17 2729.3 - 271360 - - - 0.5707 - 2.128 0.53 - 65.7 1 2 0 0.0012 20 0 0 0 3.04E+07 2.15E+07 - - - 4.0913 1 221125_WJC_METTL3_EV_vs_WT_F09.14556.14556.4 1.56E-09 13/114 R.RREEGAPGDPEAALEDNLAR.L sp|P33908|MA1A1_HUMAN 1 2165.0461 1.76 132932 14556 4 2165.051201 542.2688 "Mannosyl-oligosaccharide 1,2-alpha-mannosidase IA OS=Homo sapiens OX=9606 GN=MAN1A1 PE=1 SV=3" 4.36 2729.9 - 117618 - - - 2.3459 - 2.93 0.629 - 98.6 1 2 1 0.0051 20 0 0 0 1.87E+07 1.06E+07 - - - 5.0588 0.9132 221125_WJC_METTL3_EV_vs_WT_F09.14563.14563.3 0.0489 Jun-76 R.RREEGAPGDPEAALEDNLAR.L sp|P33908|MA1A1_HUMAN 1 2165.0461 1.22 132937 14563 3 2165.051164 722.6893 "Mannosyl-oligosaccharide 1,2-alpha-mannosidase IA OS=Homo sapiens OX=9606 GN=MAN1A1 PE=1 SV=3" 4.36 2730.9 - 78508.1 - - - 2.3288 - 1.132 0.275 - 21.7 1 2 1 0.005 20 0 0 0 8.77E+06 7.17E+06 - - - 1.9054 1 221125_WJC_METTL3_EV_vs_WT_F09.14573.14573.4 1.48E-06 14/108 R.RPGQSFHVNSEVNSVLSPR.S "sp|Q14671|PUM1_HUMAN,tr|Q5T1Z8|Q5T1Z8_HUMAN,tr|H0YEH2|H0YEH2_HUMAN,tr|Q5T1Z4|Q5T1Z4_HUMAN" 4 2109.0715 0.98 132943 14573 4 2109.074324 528.2752 Pumilio homolog 1 OS=Homo sapiens OX=9606 GN=PUM1 PE=1 SV=3 9.61 2732.2 - 146994 - - - 1.3157 - 2.64 0.535 - 130 1 2 0 0.0028 19 0 0 0 1.97E+07 2.00E+07 - - - 4.2103 1 221125_WJC_METTL3_EV_vs_WT_F09.14575.14575.3 1.60E-07 Aug-80 K.HGDEIITSTTSNYETQTFSSK[136.11].T sp|Q6P2Q9|PRP8_HUMAN 1 2353.0801 1.27 132945 14575 3 2353.081518 785.3673 Pre-mRNA-processing-splicing factor 8 OS=Homo sapiens OX=9606 GN=PRPF8 PE=1 SV=2 4.65 2732.4 - 90719.2 - - - 0.5962 - 2.165 0.62 - 51.6 1 2 0 0.0014 21 0 0 0 2.16E+07 1.71E+07 - - - 7.3038 1 221125_WJC_METTL3_EV_vs_WT_F09.14578.14578.2 8.19E-07 20-Nov R.NPEAALSPTFR[166.11].S "sp|Q86U44|MTA70_HUMAN,tr|B4E349|B4E349_HUMAN,tr|F5H6D8|F5H6D8_HUMAN,tr|B4DTN4|B4DTN4_HUMAN" 4 1211.6174 0.02 132946 14578 2 1211.618546 606.816 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 6 2732.9 - 544640 - - - 0.9401 - 2.61 0.561 - 664.7 1 2 0 0.0011 11 0 0 0 4.77E+06 2.48E+08 - - - 5.7795 0.9995 221125_WJC_METTL3_EV_vs_WT_F09.14584.14584.3 0.00264 Sep-40 R.NPEAALSPTFR[166.11].S "sp|Q86U44|MTA70_HUMAN,tr|B4E349|B4E349_HUMAN,tr|F5H6D8|F5H6D8_HUMAN,tr|B4DTN4|B4DTN4_HUMAN" 4 1211.6174 0.01 132952 14584 3 1211.616175 404.8797 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 6 2733.6 - 38999.9 - - - -1.0168 - 1.935 0.306 - 163.6 1 2 0 -0.0012 11 0 0 0 2.00E+05 1.47E+07 - - - 3.8265 0.9989 221125_WJC_METTL3_EV_vs_WT_F09.14588.14588.3 5.10E-05 Sep-76 R.R[166.11]R[166.11]EEGAPGDPEAALEDNLAR[166.11].L sp|P33908|MA1A1_HUMAN 1 2195.0709 1.67 132954 14588 3 2195.06919 732.6976 "Mannosyl-oligosaccharide 1,2-alpha-mannosidase IA OS=Homo sapiens OX=9606 GN=MAN1A1 PE=1 SV=3" 4.36 2734.2 - 112428 - - - -0.7936 - 1.605 0.426 - 36.6 1 2 1 -0.0017 20 0 0 0 8.71E+06 5.23E+06 - - - 4.4368 1 221125_WJC_METTL3_EV_vs_WT_F09.14589.14589.4 1.04E-07 13/114 K.VAHPIRPKPPSATSIPAILK.A "sp|Q9UMS4|PRP19_HUMAN,tr|F5GY56|F5GY56_HUMAN" 2 2092.2521 1.41 132955 14589 4 2092.255524 524.0703 Pre-mRNA-processing factor 19 OS=Homo sapiens OX=9606 GN=PRPF19 PE=1 SV=1 11.17 2734.3 - 506708 - - - 1.6461 - 2.425 0.516 - 94.3 1 2 0 0.0034 20 0 0 0 3.04E+07 2.15E+07 - - - 4.0125 1 221125_WJC_METTL3_EV_vs_WT_F09.14590.14590.4 1.76E-09 21/114 R.R[166.11]R[166.11]EEGAPGDPEAALEDNLAR[166.11].L sp|P33908|MA1A1_HUMAN 1 2195.0709 1.76 132956 14590 4 2195.072854 549.775 "Mannosyl-oligosaccharide 1,2-alpha-mannosidase IA OS=Homo sapiens OX=9606 GN=MAN1A1 PE=1 SV=3" 4.36 2734.4 - 294059 - - - 0.8756 - 3.12 0.648 - 212.4 1 2 1 0.0019 20 0 0 0 1.86E+07 1.06E+07 - - - 5.2461 1 221125_WJC_METTL3_EV_vs_WT_F09.14591.14591.3 1.13E-08 Nov-80 K.RPIGSWEC[160.03]SVC[160.03]C[160.03]VSNNAEDNK.C sp|P49790|NU153_HUMAN 1 2481.0471 1.94 132957 14591 3 2481.046061 828.023 Nuclear pore complex protein Nup153 OS=Homo sapiens OX=9606 GN=NUP153 PE=1 SV=2 4.68 2734.6 - 106692 - - - -0.4301 - 2.452 0.739 - 120.4 1 2 0 -0.0011 21 0 0 0 3.05E+06 1.57E+06 - - - 8.9291 0.9716 221125_WJC_METTL3_EV_vs_WT_F09.14596.14596.4 0.0407 6/108 K.DVAK[136.11]PSEEEQK[136.11]ELDEITAK[136.11].R "sp|O60508|PRP17_HUMAN,tr|Q5SRN1|Q5SRN1_HUMAN" 2 2182.1067 2.19 132960 14596 4 2182.111215 546.534 Pre-mRNA-processing factor 17 OS=Homo sapiens OX=9606 GN=CDC40 PE=1 SV=1 4.25 2735.3 - 73923.2 - - - 2.0581 - 1.189 0.25 - 15.1 1 2 1 0.0045 19 0 0 0 4.07E+06 1.86E+06 - - - 1.4593 1 221125_WJC_METTL3_EV_vs_WT_F09.14599.14599.3 1.80E-09 Aug-80 K.R[166.11]PIGSWEC[160.03]SVC[160.03]C[160.03]VSNNAEDNK[136.11].C sp|P49790|NU153_HUMAN 1 2499.0696 1.94 132963 14599 3 2499.074926 834.0305 Nuclear pore complex protein Nup153 OS=Homo sapiens OX=9606 GN=NUP153 PE=1 SV=2 4.68 2735.6 - 101121 - - - 2.132 - 2.312 0.689 - 51.1 1 2 0 0.0053 21 0 0 0 3.05E+06 1.57E+06 - - - 8.2295 1 221125_WJC_METTL3_EV_vs_WT_F09.14606.14606.3 6.22E-09 16/72 R.R[166.11]PGQSFHVNSEVNSVLSPR[166.11].S "sp|Q14671|PUM1_HUMAN,tr|Q5T1Z8|Q5T1Z8_HUMAN,tr|H0YEH2|H0YEH2_HUMAN,tr|Q5T1Z4|Q5T1Z4_HUMAN" 4 2129.0881 2.38 132968 14606 3 2129.089032 710.7033 Pumilio homolog 1 OS=Homo sapiens OX=9606 GN=PUM1 PE=1 SV=3 9.61 2736.6 - 80192 - - - 0.4429 - 3.144 0.598 - 347.3 1 2 0 0.0009 19 0 0 0 1.08E+07 4.54E+06 - - - 8.0211 0.9434 221125_WJC_METTL3_EV_vs_WT_F09.14611.14611.4 0.264 Jun-90 K.K[136.11]K[136.11]EPEPNFQLLDNPAR[166.11].V "sp|Q99460|PSMD1_HUMAN,tr|A0A7I2V2K8|A0A7I2V2K8_HUMAN,tr|A0A7I2YQY1|A0A7I2YQY1_HUMAN,tr|A0A7I2V523|A0A7I2V523_HUMAN,tr|A0A7I2V641|A0A7I2V641_HUMAN,tr|A0A7I2V262|A0A7I2V262_HUMAN,tr|A0A087WW66|A0A087WW66_HUMAN,tr|A0A7P0MW50|A0A7P0MW50_HUMAN,tr|A0A7I2V5C8|A0A7I2V5C8_HUMAN,tr|A0A7I2V479|A0A7I2V479_HUMAN" 10 1921.0268 0.59 132971 14611 4 1921.024649 481.264 26S proteasome non-ATPase regulatory subunit 1 OS=Homo sapiens OX=9606 GN=PSMD1 PE=1 SV=2 6.18 2737.3 - 60615.4 - - - -1.1098 - 1.033 0.206 - 22.3 1 2 1 -0.0021 16 0 0 0 1.57E+06 2.66E+06 - - - 1.0299 0.9999 221125_WJC_METTL3_EV_vs_WT_F09.14624.14624.4 0.00574 13/102 K.QFTPC[160.03]QLLADHANSPNKK.F "sp|P40939|ECHA_HUMAN,tr|H0YFD6|H0YFD6_HUMAN,tr|A0A2R8Y4F5|A0A2R8Y4F5_HUMAN" 3 2068.016 0.71 132979 14624 4 2068.014963 518.0113 "Trifunctional enzyme subunit alpha, mitochondrial OS=Homo sapiens OX=9606 GN=HADHA PE=1 SV=2" 8.21 2739 - 304901 - - - -0.5058 - 2.326 0.463 - 71.5 1 2 0 -0.001 18 0 0 0 6.77E+06 9.49E+06 - - - 3.5448 0.9998 221125_WJC_METTL3_EV_vs_WT_F09.14630.14630.3 0.000203 Jul-52 K.K[136.11]GPGEVAGTVTGQK[136.11].R "sp|Q86U44|MTA70_HUMAN,tr|F5H6D8|F5H6D8_HUMAN,tr|H0YFV6|H0YFV6_HUMAN,tr|B4DTN4|B4DTN4_HUMAN" 4 1343.738 0.01 132983 14630 3 1343.738534 448.9199 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 8.59 2739.8 - 127077 - - - 0.413 - 1.735 0.429 - 81.5 1 2 0 0.0006 14 0 0 0 5.32E+04 6.76E+06 - - - 4.7871 1 221125_WJC_METTL3_EV_vs_WT_F09.14641.14641.3 7.10E-10 14/112 K.SHVEDGDIAGAPASSPEAPPAEQDPVQLK[136.11].T "sp|Q9P2E9|RRBP1_HUMAN,tr|A0A087WU26|A0A087WU26_HUMAN,tr|A0A087WVV2|A0A087WVV2_HUMAN,tr|F8W7S5|F8W7S5_HUMAN" 4 2919.3978 1.58 132989 14641 3 2919.399074 974.1399 Ribosome-binding protein 1 OS=Homo sapiens OX=9606 GN=RRBP1 PE=1 SV=5 4.01 2741.5 - 141970 - - - 0.4501 - 2.837 0.711 - 115.1 1 2 0 0.0013 29 0 0 0 3.22E+07 2.04E+07 - - - 8.8656 0.9996 221125_WJC_METTL3_EV_vs_WT_F09.14652.14652.2 4.32E-07 20-Jul R.NPEAALSPTFR.S "sp|Q86U44|MTA70_HUMAN,tr|B4E349|B4E349_HUMAN,tr|F5H6D8|F5H6D8_HUMAN,tr|B4DTN4|B4DTN4_HUMAN" 4 1201.6091 0.02 132995 14652 2 1201.606229 601.8118 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 6 2743 - 142400 - - - -2.4201 - 1.773 0.54 - 144.9 1 2 0 -0.0029 11 0 0 0 4.77E+06 2.46E+08 - - - 4.5777 0.9412 221125_WJC_METTL3_EV_vs_WT_F09.14659.14659.2 0.544 20-May R.TNAENEFVTIK.K sp|P04264|K2C1_HUMAN 1 1264.6299 999 132998 14659 2 1264.629232 633.3222 "Keratin, type II cytoskeletal 1 OS=Homo sapiens OX=9606 GN=KRT1 PE=1 SV=6" 4.53 2744 - 72906.8 - - - -0.5535 - 1.032 0.048 - 87.5 1 2 0 -0.0007 11 0 0 0 9.27E+06 0.00E+00 - - - -0.5195 0.9199 221125_WJC_METTL3_EV_vs_WT_F09.14660.14660.3 0.523 May-92 R.TTTPNMNPAINYQPQSSSSVPC[160.03]QR[166.11].T sp|Q8WXI9|P66B_HUMAN 1 2687.2307 2.83 132999 14660 3 2687.233044 896.7508 Transcriptional repressor p66-beta OS=Homo sapiens OX=9606 GN=GATAD2B PE=1 SV=1 7.89 2744.1 - 48546.7 - - - 0.8652 - 1.034 0.178 - 19.9 1 2 0 0.0023 24 0 0 0 4.76E+06 1.68E+06 - - - 0.6015 1 221125_WJC_METTL3_EV_vs_WT_F09.14663.14663.3 4.57E-09 14/96 K.TPVVQNAASIVQPSPAHVGQQGLSK.L "sp|Q8WXI9|P66B_HUMAN,tr|A0A0U1RRM1|A0A0U1RRM1_HUMAN" 2 2512.3398 1.9 133000 14663 3 2512.34516 838.4539 Transcriptional repressor p66-beta OS=Homo sapiens OX=9606 GN=GATAD2B PE=1 SV=1 8.44 2744.6 - 170659 - - - 2.1394 - 3.548 0.663 - 129.5 1 2 0 0.0054 25 0 0 0 1.51E+07 7.95E+06 - - - 8.8438 0.9976 221125_WJC_METTL3_EV_vs_WT_F09.14670.14670.3 0.135 Jun-92 R.TTTPNMNPAINYQPQSSSSVPC[160.03]QR.T sp|Q8WXI9|P66B_HUMAN 1 2677.2224 2.83 133005 14670 3 2677.230148 893.4148 Transcriptional repressor p66-beta OS=Homo sapiens OX=9606 GN=GATAD2B PE=1 SV=1 7.89 2745.6 - 65434.8 - - - 2.8757 - 1.228 0.41 - 21.2 1 2 0 0.0077 24 0 0 0 4.76E+06 1.68E+06 - - - 3.586 0.9999 221125_WJC_METTL3_EV_vs_WT_F09.14699.14699.4 0.000278 10/108 R.GLLQDDAHPTLVTYADHSK[136.11].L "sp|Q86U44|MTA70_HUMAN,tr|F5H6D8|F5H6D8_HUMAN,tr|H0YFV6|H0YFV6_HUMAN,tr|B4DTN4|B4DTN4_HUMAN" 4 2088.0367 0.51 133019 14699 4 2088.04124 523.0165 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 5.13 2749.7 - 360131 - - - 2.1585 - 2.032 0.448 - 72.2 1 2 0 0.0045 19 0 0 0 5.69E+06 1.11E+07 - - - 3.364 0.9787 221125_WJC_METTL3_EV_vs_WT_F09.14705.14705.4 0.0213 Sep-84 K.KKPIYINVIRDPIER.L "sp|Q7LGA3|HS2ST_HUMAN,tr|K7EP71|K7EP71_HUMAN" 2 1853.0887 1.04 133023 14705 4 1853.093771 464.2795 Heparan sulfate 2-O-sulfotransferase 1 OS=Homo sapiens OX=9606 GN=HS2ST1 PE=1 SV=1 9.7 2750.5 - 140328 - - - 2.7349 - 1.469 0.274 - 39.1 1 2 1 0.0051 15 0 0 0 3.30E+06 3.17E+06 - - - 1.7471 0.9997 221125_WJC_METTL3_EV_vs_WT_F09.14715.14715.3 0.00111 Aug-72 R.GLLQDDAHPTLVTYADHSK[136.11].L "sp|Q86U44|MTA70_HUMAN,tr|F5H6D8|F5H6D8_HUMAN,tr|H0YFV6|H0YFV6_HUMAN,tr|B4DTN4|B4DTN4_HUMAN" 4 2088.0367 0.02 133029 14715 3 2088.037546 697.0195 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 5.13 2751.9 - 146754 - - - 0.3894 - 1.631 0.412 - 68.8 1 2 0 0.0008 19 0 0 0 1.06E+05 4.60E+06 - - - 4.335 0.8404 221125_WJC_METTL3_EV_vs_WT_F09.14727.14727.2 1.20E-06 Nov-32 V.SGLNSSASEPAK[136.11]EPAK[136.11]K[136.11].S "sp|Q86U44|MTA70_HUMAN,tr|F5H6D8|F5H6D8_HUMAN,tr|H0YFV6|H0YFV6_HUMAN,tr|B4DTN4|B4DTN4_HUMAN" 4 1723.9167 0.001 133036 14727 2 1723.912427 862.9656 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 8.22 2753.6 - 37124.7 - - - -2.4659 - 2.426 0.563 - 277.9 1 1 1 -0.0043 17 0 0 0 0.00E+00 2.14E+06 - - - 5.3769 0.9749 221125_WJC_METTL3_EV_vs_WT_F09.14731.14731.3 0.0165 Dec-84 F.ASSLVSGLNSSASEPAK[136.11]EPAK[136.11]K[136.11].S "sp|Q86U44|MTA70_HUMAN,tr|F5H6D8|F5H6D8_HUMAN,tr|H0YFV6|H0YFV6_HUMAN,tr|B4DTN4|B4DTN4_HUMAN" 4 2181.1703 0.001 133038 14731 3 2181.169654 728.0641 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 8.54 2754.2 - 84024.3 - - - -0.3085 - 2.59 0.452 - 120.1 1 1 1 -0.0007 22 0 0 0 0.00E+00 4.58E+06 - - - 5.8354 0.9987 221125_WJC_METTL3_EV_vs_WT_F09.14732.14732.3 0.000227 Aug-64 R.TKENDAHLVEVNLNNIK.N "sp|Q9NYL9|TMOD3_HUMAN,tr|H0YKU1|H0YKU1_HUMAN,tr|H0YNJ8|H0YNJ8_HUMAN" 3 1950.0171 1.12 133039 14732 3 1950.023123 651.013 Tropomodulin-3 OS=Homo sapiens OX=9606 GN=TMOD3 PE=1 SV=1 5.41 2754.3 - 104958 - - - 3.1123 - 2.068 0.466 - 81.5 1 2 1 0.0061 17 0 0 0 6.24E+06 5.60E+06 - - - 5.5693 0.9782 221125_WJC_METTL3_EV_vs_WT_F09.14733.14733.4 0.13 8/144 R.SEAEEAITSFNGHKPPGSSEPITVK.F sp|Q15717|ELAV1_HUMAN 1 2611.2766 1.53 133040 14733 4 2611.281101 653.8264 ELAV-like protein 1 OS=Homo sapiens OX=9606 GN=ELAVL1 PE=1 SV=2 4.9 2754.4 - 103039 - - - 1.7329 - 1.448 0.19 - 27.1 1 2 0 0.0045 25 0 0 0 3.23E+08 2.12E+08 - - - 0.9963 0.9999 221125_WJC_METTL3_EV_vs_WT_F09.14738.14738.3 1.14E-07 Dec-64 R.TK[136.11]ENDAHLVEVNLNNIK[136.11].N "sp|Q9NYL9|TMOD3_HUMAN,tr|H0YKU1|H0YKU1_HUMAN,tr|H0YNJ8|H0YNJ8_HUMAN" 3 1966.0455 1.14 133043 14738 3 1966.043736 656.3558 Tropomodulin-3 OS=Homo sapiens OX=9606 GN=TMOD3 PE=1 SV=1 5.41 2755 - 159664 - - - -0.8738 - 2.811 0.573 - 108 1 2 1 -0.0017 17 0 0 0 6.36E+06 5.60E+06 - - - 7.5389 0.9898 221125_WJC_METTL3_EV_vs_WT_F09.14739.14739.4 0.0258 5/138 R.KLSYAEVC[160.03]QKPPKEPSSVLVQPLR.E "sp|Q71RC2|LARP4_HUMAN,tr|X6RLN4|X6RLN4_HUMAN" 2 2752.4946 1.25 133044 14739 4 2752.49246 689.1309 La-related protein 4 OS=Homo sapiens OX=9606 GN=LARP4 PE=1 SV=3 9.11 2755.2 - 89185.9 - - - -0.7673 - 1.164 0.275 - 16.6 1 2 1 -0.0021 24 0 0 0 3.03E+06 2.41E+06 - - - 1.6678 0.9986 221125_WJC_METTL3_EV_vs_WT_F09.14742.14742.3 0.0102 Jul-56 R.STSHK[136.11]PDEIYGMIER[166.11].L sp|Q86U44|MTA70_HUMAN 1 1779.8581 0.04 133046 14742 3 1779.858741 594.2933 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 5.42 2755.6 - 157297 - - - 0.386 - 1.441 0.32 - 64.7 1 2 0 0.0007 15 0 0 0 1.70E+05 4.06E+06 - - - 3.0608 0.9998 221125_WJC_METTL3_EV_vs_WT_F09.14758.14758.4 0.000329 14/96 R.TKENDAHLVEVNLNNIK.N "sp|Q9NYL9|TMOD3_HUMAN,tr|H0YKU1|H0YKU1_HUMAN,tr|H0YNJ8|H0YNJ8_HUMAN" 3 1950.0171 1.16 133053 14758 4 1950.016213 488.5115 Tropomodulin-3 OS=Homo sapiens OX=9606 GN=TMOD3 PE=1 SV=1 5.41 2757.7 - 293465 - - - -0.4313 - 2.882 0.459 - 216.5 1 2 1 -0.0008 17 0 0 0 8.26E+06 7.10E+06 - - - 3.5884 0.9976 221125_WJC_METTL3_EV_vs_WT_F09.14760.14760.3 8.76E-09 17/72 K.PSTASAVPELATDPELEK[136.11]K[136.11].L "sp|Q86U44|MTA70_HUMAN,tr|B4E349|B4E349_HUMAN,tr|F5H6D8|F5H6D8_HUMAN,tr|H0YFV6|H0YFV6_HUMAN,tr|B4DTN4|B4DTN4_HUMAN" 5 1998.0492 0.001 133054 14760 3 1998.047573 667.0237 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 4.41 2758 - 391263 - - - -0.8153 - 3.056 0.502 - 282.2 1 1 0 -0.0016 19 0 0 0 0.00E+00 3.43E+07 - - - 6.8809 0.9996 221125_WJC_METTL3_EV_vs_WT_F09.14767.14767.4 0.0122 9/108 K.QYYIGDIHPSDLKPESGSK.D "sp|O43169|CYB5B_HUMAN,tr|H3BUX2|H3BUX2_HUMAN" 2 2133.0378 1.17 133058 14767 4 2133.039612 534.2667 Cytochrome b5 type B OS=Homo sapiens OX=9606 GN=CYB5B PE=1 SV=3 5.38 2759 - 289368 - - - 0.8265 - 1.987 0.352 - 41.9 1 2 0 0.0018 19 0 0 0 1.64E+07 1.41E+07 - - - 2.5216 0.9996 221125_WJC_METTL3_EV_vs_WT_F09.14772.14772.4 0.00102 8/126 K.THIQDNHDGTYTVAYVPDVTGR[166.11].Y "sp|P21333|FLNA_HUMAN,tr|Q60FE5|Q60FE5_HUMAN" 2 2468.1596 0.09 133059 14772 4 2468.160907 618.0472 Filamin-A OS=Homo sapiens OX=9606 GN=FLNA PE=1 SV=4 5.12 2759.8 - 168465 - - - 0.5352 - 1.848 0.345 - 29.7 1 2 0 0.0013 22 0 0 0 4.76E+05 5.08E+06 - - - 2.4295 0.9999 221125_WJC_METTL3_EV_vs_WT_F09.14773.14773.3 0.00144 Aug-80 R.R[166.11]VNSASSSNPPAEVDPDTILK[136.11].A "sp|Q9BY77|PDIP3_HUMAN,tr|F6VRR5|F6VRR5_HUMAN" 2 2214.1247 1.81 133060 14773 3 2214.127552 739.0488 Polymerase delta-interacting protein 3 OS=Homo sapiens OX=9606 GN=POLDIP3 PE=1 SV=2 4.56 2759.9 - 174795 - - - 1.2836 - 2.034 0.486 - 54.1 1 2 0 0.0028 21 0 0 0 7.87E+07 4.34E+07 - - - 5.6598 1 221125_WJC_METTL3_EV_vs_WT_F09.14774.14774.3 1.06E-06 29/84 K.DHTPSQELALTQSVGGDSSADR[166.11].L "sp|Q86U44|MTA70_HUMAN,tr|H0YFV6|H0YFV6_HUMAN" 2 2280.0494 0.03 133061 14774 3 2280.041829 761.0237 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 4.22 2760 - 1.86E+06 - - - -3.3061 - 4.971 0.637 - 933.4 1 2 0 -0.0075 22 0 0 0 3.79E+06 1.21E+08 - - - 9.4418 1 221125_WJC_METTL3_EV_vs_WT_F09.14775.14775.4 1.33E-08 15/114 K.R[166.11]GLLQDDAHPTLVTYADHSK[136.11].L "sp|Q86U44|MTA70_HUMAN,tr|F5H6D8|F5H6D8_HUMAN,tr|H0YFV6|H0YFV6_HUMAN,tr|B4DTN4|B4DTN4_HUMAN" 4 2254.1461 0.24 133062 14775 4 2254.147505 564.5438 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 5.99 2760.1 - 181453 - - - 0.6166 - 2.947 0.533 - 181.1 1 2 0 0.0014 20 0 0 0 2.04E+06 8.65E+06 - - - 4.2262 0.9997 221125_WJC_METTL3_EV_vs_WT_F09.14778.14778.3 0.00397 Jul-72 K.QYYIGDIHPSDLKPESGSK.D "sp|O43169|CYB5B_HUMAN,tr|H3BUX2|H3BUX2_HUMAN" 2 2133.0378 1.08 133063 14778 3 2133.038602 712.0199 Cytochrome b5 type B OS=Homo sapiens OX=9606 GN=CYB5B PE=1 SV=3 5.38 2760.6 - 124907 - - - 0.353 - 1.476 0.414 - 48.8 1 2 0 0.0008 19 0 0 0 5.42E+06 5.00E+06 - - - 4.112 0.9608 221125_WJC_METTL3_EV_vs_WT_F09.14785.14785.2 2.52 12-Apr K.ITELLNK.T "sp|Q9UIF9|BAZ2A_HUMAN,tr|H0YII3|H0YII3_HUMAN,tr|F8VU39|F8VU39_HUMAN,tr|B5MC86|B5MC86_HUMAN,tr|J3KPG5|J3KPG5_HUMAN" 5 829.4909 999 133067 14785 2 829.490736 415.7527 Bromodomain adjacent to zinc finger domain protein 2A OS=Homo sapiens OX=9606 GN=BAZ2A PE=1 SV=4 6 2761.4 - 68010.6 - - - -0.2206 - 0.835 0.169 - 53.1 1 2 0 -0.0002 7 0 0 0 1.56E+06 0.00E+00 - - - -0.2822 0.999 221125_WJC_METTL3_EV_vs_WT_F09.14786.14786.3 0.0779 Jul-72 K.QYYIGDIHPSDLK[136.11]PESGSK[136.11].D "sp|O43169|CYB5B_HUMAN,tr|H3BUX2|H3BUX2_HUMAN" 2 2149.0662 1.09 133068 14786 3 2149.065155 717.3627 Cytochrome b5 type B OS=Homo sapiens OX=9606 GN=CYB5B PE=1 SV=3 5.38 2761.5 - 132378 - - - -0.5091 - 1.652 0.32 - 48 1 2 0 -0.0011 19 0 0 0 5.42E+06 4.96E+06 - - - 3.3407 0.9999 221125_WJC_METTL3_EV_vs_WT_F09.14806.14806.3 0.00011 Aug-96 R.SEAEEAITSFNGHKPPGSSEPITVK.F sp|Q15717|ELAV1_HUMAN 1 2611.2766 1.55 133081 14806 3 2611.276598 871.4328 ELAV-like protein 1 OS=Homo sapiens OX=9606 GN=ELAVL1 PE=1 SV=2 4.9 2764.1 - 125720 - - - 0.0084 - 1.906 0.5 - 44.8 1 2 0 0 25 0 0 0 6.06E+07 3.91E+07 - - - 5.5984 0.9993 221125_WJC_METTL3_EV_vs_WT_F09.14808.14808.3 0.00045 May-96 R.SEAEEAITSFNGHK[136.11]PPGSSEPITVK[136.11].F sp|Q15717|ELAV1_HUMAN 1 2627.305 1.55 133083 14808 3 2627.297935 876.7756 ELAV-like protein 1 OS=Homo sapiens OX=9606 GN=ELAVL1 PE=1 SV=2 4.9 2764.3 - 87718.6 - - - -2.6799 - 1.613 0.432 - 18.5 1 2 0 -0.007 25 0 0 0 6.05E+07 3.91E+07 - - - 4.4543 1 221125_WJC_METTL3_EV_vs_WT_F09.14813.14813.3 6.96E-11 22/80 R.RVNSASSSNPPAEVDPDTILK.A "sp|Q9BY77|PDIP3_HUMAN,tr|F6VRR5|F6VRR5_HUMAN" 2 2196.1022 1.82 133087 14813 3 2196.100487 733.0414 Polymerase delta-interacting protein 3 OS=Homo sapiens OX=9606 GN=POLDIP3 PE=1 SV=2 4.56 2764.9 - 657486 - - - -0.7982 - 3.693 0.597 - 439.8 1 2 0 -0.0018 21 0 0 0 7.89E+07 4.34E+07 - - - 8.3276 0.9914 221125_WJC_METTL3_EV_vs_WT_F09.14820.14820.4 0.173 6/114 R.LK[136.11]PDEGGEVPVLNVSYK[136.11]PQK[136.11].L "sp|P61221|ABCE1_HUMAN,tr|D6R9I9|D6R9I9_HUMAN" 2 2220.2216 1.1 133091 14820 4 2220.223509 556.0627 ATP-binding cassette sub-family E member 1 OS=Homo sapiens OX=9606 GN=ABCE1 PE=1 SV=1 6.18 2765.9 - 97768.6 - - - 0.8445 - 1.182 0.223 - 15.6 1 2 0 0.0019 20 0 0 0 2.59E+06 2.35E+06 - - - 1.2224 1 221125_WJC_METTL3_EV_vs_WT_F09.14826.14826.4 1.20E-11 23/138 A.AFASSLVSGLNSSASEPAK[136.11]EPAK[136.11]K[136.11].S "sp|Q86U44|MTA70_HUMAN,tr|F5H6D8|F5H6D8_HUMAN,tr|H0YFV6|H0YFV6_HUMAN,tr|B4DTN4|B4DTN4_HUMAN" 4 2399.2759 0 133095 14826 4 2399.27774 600.8262 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 8.54 2766.7 - 4.13E+06 - - - 0.7857 - 4.08 0.646 - 343.8 1 1 1 0.0019 24 0 0 0 8.55E+05 9.30E+08 - - - 5.2996 0.9999 221125_WJC_METTL3_EV_vs_WT_F09.14831.14831.3 0.000378 Oct-40 R.AVFPSIVGRPR.Q "sp|Q6S8J3|POTEE_HUMAN,sp|P63261|ACTG_HUMAN,sp|P68133|ACTS_HUMAN,sp|P62736|ACTA_HUMAN,sp|Q9BYX7|ACTBM_HUMAN,sp|P68032|ACTC_HUMAN,sp|P60709|ACTB_HUMAN,sp|P63267|ACTH_HUMAN,sp|A5A3E0|POTEF_HUMAN,sp|P0CG38|POTEI_HUMAN,tr|A0A804GS07|A0A804GS07_HUMAN,tr|I3L3I0|I3L3I0_HUMAN,tr|G5E9R0|G5E9R0_HUMAN,tr|E7EVS6|E7EVS6_HUMAN,tr|B8ZZJ2|B8ZZJ2_HUMAN,tr|J3KT65|J3KT65_HUMAN,tr|I3L3R2|I3L3R2_HUMAN,tr|K7EM38|K7EM38_HUMAN,tr|F6QUT6|F6QUT6_HUMAN,tr|C9JTX5|C9JTX5_HUMAN,tr|A0A6Q8PH58|A0A6Q8PH58_HUMAN,tr|F6UVQ4|F6UVQ4_HUMAN,tr|F8WB63|F8WB63_HUMAN,tr|I3L1U9|I3L1U9_HUMAN,tr|A0A2R8Y793|A0A2R8Y793_HUMAN,tr|I3L4N8|I3L4N8_HUMAN,tr|C9JUM1|C9JUM1_HUMAN,tr|F8WCH0|F8WCH0_HUMAN,tr|C9JZR7|C9JZR7_HUMAN,tr|C9JFL5|C9JFL5_HUMAN,tr|A0A2R8YGF8|A0A2R8YGF8_HUMAN,tr|A6NL76|A6NL76_HUMAN" 32 1197.6982 2.46 133098 14831 3 1197.69958 400.24 POTE ankyrin domain family member E OS=Homo sapiens OX=9606 GN=POTEE PE=2 SV=3 12 2767.4 - 180070 - - - 1.1305 - 2.086 0.463 - 147.5 1 2 0 0.0014 11 0 0 0 9.64E+06 3.91E+06 - - - 5.7903 0.9997 221125_WJC_METTL3_EV_vs_WT_F09.14838.14838.4 1.16E-06 13/138 K.AVHTVDFTADK[136.11]YHVVSGADDYTVK[136.11].L "sp|Q8TED0|UTP15_HUMAN,tr|H0Y8P4|H0Y8P4_HUMAN" 2 2653.2995 1.46 133103 14838 4 2653.306522 664.3322 U3 small nucleolar RNA-associated protein 15 homolog OS=Homo sapiens OX=9606 GN=UTP15 PE=1 SV=3 5.2 2768.4 - 231023 - - - 2.6476 - 2.724 0.509 - 86.7 1 2 1 0.007 24 0 0 0 1.74E+06 1.19E+06 - - - 3.976 0.9388 221125_WJC_METTL3_EV_vs_WT_F09.14844.14844.3 0.0295 Jul-92 K.ELQQAQTTRPESTQIQPQPGFC[160.03]IK.T "sp|Q9NWS0|PIHD1_HUMAN,tr|M0QYF4|M0QYF4_HUMAN,tr|M0QXD5|M0QXD5_HUMAN,tr|M0R3A8|M0R3A8_HUMAN,tr|M0R0J2|M0R0J2_HUMAN,tr|M0QYA2|M0QYA2_HUMAN" 6 2784.3865 1.42 133107 14844 3 2784.392651 929.1361 PIH1 domain-containing protein 1 OS=Homo sapiens OX=9606 GN=PIH1D1 PE=1 SV=1 6.23 2769.2 - 98980 - - - 2.217 - 1.652 0.133 - 28.7 1 2 0 0.0062 24 0 0 0 4.18E+07 2.95E+07 - - - 1.187 0.9998 221125_WJC_METTL3_EV_vs_WT_F09.14851.14851.4 1.64E-05 10/138 K.AVHTVDFTADKYHVVSGADDYTVK.L "sp|Q8TED0|UTP15_HUMAN,tr|H0Y8P4|H0Y8P4_HUMAN" 2 2637.2711 1.46 133111 14851 4 2637.268706 660.3251 U3 small nucleolar RNA-associated protein 15 homolog OS=Homo sapiens OX=9606 GN=UTP15 PE=1 SV=3 5.2 2770.2 - 168379 - - - -0.9066 - 2.399 0.461 - 54.4 1 2 1 -0.0024 24 0 0 0 1.74E+06 1.19E+06 - - - 3.5187 1 221125_WJC_METTL3_EV_vs_WT_F09.14852.14852.3 7.67E-06 Sep-52 K.K[136.11]GPGEVAGTVTGQK[136.11].R "sp|Q86U44|MTA70_HUMAN,tr|F5H6D8|F5H6D8_HUMAN,tr|H0YFV6|H0YFV6_HUMAN,tr|B4DTN4|B4DTN4_HUMAN" 4 1343.738 0 133112 14852 3 1343.740236 448.9199 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 8.59 2770.3 - 120629 - - - 1.6796 - 1.936 0.588 - 90.1 1 2 0 0.0023 14 0 0 0 3.45E+04 6.95E+06 - - - 6.8506 1 221125_WJC_METTL3_EV_vs_WT_F09.14854.14854.3 0.000619 13/84 R.TSR[166.11]PENAIIYNNNEDFQVGQAK[136.11].V "sp|P29401|TKT_HUMAN,tr|A0A0B4J1R6|A0A0B4J1R6_HUMAN" 2 2525.2265 1.11 133114 14854 3 2525.229151 842.7495 Transketolase OS=Homo sapiens OX=9606 GN=TKT PE=1 SV=3 4.68 2770.6 - 79019.2 - - - 1.03 - 2.588 0.562 - 188.1 1 2 0 0.0026 22 0 0 0 4.08E+06 3.66E+06 - - - 7.0594 0.997 221125_WJC_METTL3_EV_vs_WT_F09.14859.14859.2 0.0981 12-Jul K.FASFIDK.V "sp|Q86Y46|K2C73_HUMAN,sp|Q7RTS7|K2C74_HUMAN,sp|Q9NSB2|KRT84_HUMAN,sp|P48668|K2C6C_HUMAN,sp|Q3SY84|K2C71_HUMAN,sp|P05787|K2C8_HUMAN,sp|Q01546|K22O_HUMAN,sp|P19013|K2C4_HUMAN,sp|Q7Z794|K2C1B_HUMAN,sp|Q8N1N4|K2C78_HUMAN,sp|P12035|K2C3_HUMAN,sp|P04264|K2C1_HUMAN,sp|P04259|K2C6B_HUMAN,sp|P13647|K2C5_HUMAN,sp|P35908|K22E_HUMAN,sp|Q14CN4|K2C72_HUMAN,sp|P08729|K2C7_HUMAN,sp|O95678|K2C75_HUMAN,sp|Q5XKE5|K2C79_HUMAN,sp|P02538|K2C6A_HUMAN,tr|F8VUG2|F8VUG2_HUMAN,tr|F8W0C6|F8W0C6_HUMAN,tr|F8W1U3|F8W1U3_HUMAN,tr|H0YHD9|H0YHD9_HUMAN,tr|F8W1S1|F8W1S1_HUMAN,tr|F8VS61|F8VS61_HUMAN" 26 826.4225 178.22 133117 14859 2 826.421897 414.2185 "Keratin, type II cytoskeletal 73 OS=Homo sapiens OX=9606 GN=KRT73 PE=1 SV=1" 5.84 2771.3 - 147614 - - - -0.7357 - 1.383 0.201 - 128 1 2 0 -0.0006 7 0 0 0 1.19E+07 6.70E+04 - - - 1.5528 0.9978 221125_WJC_METTL3_EV_vs_WT_F09.14865.14865.3 0.0711 Jun-40 R.AVFPSIVGR[166.11]PR[166.11].Q "sp|Q6S8J3|POTEE_HUMAN,sp|P63261|ACTG_HUMAN,sp|P68133|ACTS_HUMAN,sp|P62736|ACTA_HUMAN,sp|Q9BYX7|ACTBM_HUMAN,sp|P68032|ACTC_HUMAN,sp|P60709|ACTB_HUMAN,sp|P63267|ACTH_HUMAN,sp|A5A3E0|POTEF_HUMAN,sp|P0CG38|POTEI_HUMAN,tr|A0A804GS07|A0A804GS07_HUMAN,tr|I3L3I0|I3L3I0_HUMAN,tr|G5E9R0|G5E9R0_HUMAN,tr|E7EVS6|E7EVS6_HUMAN,tr|B8ZZJ2|B8ZZJ2_HUMAN,tr|J3KT65|J3KT65_HUMAN,tr|I3L3R2|I3L3R2_HUMAN,tr|K7EM38|K7EM38_HUMAN,tr|F6QUT6|F6QUT6_HUMAN,tr|C9JTX5|C9JTX5_HUMAN,tr|A0A6Q8PH58|A0A6Q8PH58_HUMAN,tr|F6UVQ4|F6UVQ4_HUMAN,tr|F8WB63|F8WB63_HUMAN,tr|I3L1U9|I3L1U9_HUMAN,tr|A0A2R8Y793|A0A2R8Y793_HUMAN,tr|I3L4N8|I3L4N8_HUMAN,tr|C9JUM1|C9JUM1_HUMAN,tr|F8WCH0|F8WCH0_HUMAN,tr|C9JZR7|C9JZR7_HUMAN,tr|C9JFL5|C9JFL5_HUMAN,tr|A0A2R8YGF8|A0A2R8YGF8_HUMAN,tr|A6NL76|A6NL76_HUMAN" 32 1217.7148 2.47 133121 14865 3 1217.716859 406.9122 POTE ankyrin domain family member E OS=Homo sapiens OX=9606 GN=POTEE PE=2 SV=3 12 2772.1 - 60757.3 - - - 1.7188 - 1.251 0.351 - 59 1 2 0 0.0021 11 0 0 0 9.63E+06 3.90E+06 - - - 3.0889 0.9905 221125_WJC_METTL3_EV_vs_WT_F09.14871.14871.2 1.48E-05 22-Sep A.VPELATDPELEK[136.11].K "sp|Q86U44|MTA70_HUMAN,tr|B4E349|B4E349_HUMAN,tr|F5H6D8|F5H6D8_HUMAN,tr|H0YFV6|H0YFV6_HUMAN,tr|B4DTN4|B4DTN4_HUMAN" 5 1347.7013 0 133127 14871 2 1347.700025 674.8579 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 4 2772.8 - 62199.5 - - - -0.955 - 1.885 0.534 - 249.2 1 1 0 -0.0013 12 0 0 0 1.85E+04 7.89E+06 - - - 4.6527 1 221125_WJC_METTL3_EV_vs_WT_F09.14874.14874.3 9.32E-08 15/84 R.TSRPENAIIYNNNEDFQVGQAK.V "sp|P29401|TKT_HUMAN,tr|A0A0B4J1R6|A0A0B4J1R6_HUMAN" 2 2507.2041 1.11 133128 14874 3 2507.207859 836.742 Transketolase OS=Homo sapiens OX=9606 GN=TKT PE=1 SV=3 4.68 2773.3 - 276203 - - - 1.5073 - 2.992 0.652 - 278.7 1 2 0 0.0038 22 0 0 0 4.08E+06 3.66E+06 - - - 8.4064 0.999 221125_WJC_METTL3_EV_vs_WT_F09.14879.14879.4 0.105 13/138 K.ELQQAQTTRPESTQIQPQPGFC[160.03]IK.T "sp|Q9NWS0|PIHD1_HUMAN,tr|M0QYF4|M0QYF4_HUMAN,tr|M0QXD5|M0QXD5_HUMAN,tr|M0R3A8|M0R3A8_HUMAN,tr|M0R0J2|M0R0J2_HUMAN,tr|M0QYA2|M0QYA2_HUMAN" 6 2784.3865 1.28 133131 14879 4 2784.390446 697.1039 PIH1 domain-containing protein 1 OS=Homo sapiens OX=9606 GN=PIH1D1 PE=1 SV=1 6.23 2774 - 296764 - - - 1.4251 - 1.891 0.309 - 64 1 2 0 0.004 24 0 0 0 8.91E+06 6.98E+06 - - - 2.1189 0.946 221125_WJC_METTL3_EV_vs_WT_F09.14882.14882.4 0.00245 10/132 R.KVTFFEPGSGDENGTSNKEDEFR.M "sp|O95793|STAU1_HUMAN,tr|Q5JW30|Q5JW30_HUMAN" 2 2589.1619 6.27 133134 14882 4 2590.153374 648.2978 Double-stranded RNA-binding protein Staufen homolog 1 OS=Homo sapiens OX=9606 GN=STAU1 PE=1 SV=2 4.36 2774.4 - 163460 - - - 382.917 - 1.758 0.526 - 52 1 2 1 0.9914 23 0 0 0 8.86E+05 1.41E+05 - - - 3.7125 0.8157 221125_WJC_METTL3_EV_vs_WT_F09.14886.14886.4 4.54 5/108 R.SFFHQHYLGGQEPTPSNIR.M "sp|P46379|BAG6_HUMAN,tr|A0A7I2V508|A0A7I2V508_HUMAN,tr|A0A7P0MQS5|A0A7P0MQS5_HUMAN,tr|A0A0G2JL47|A0A0G2JL47_HUMAN,tr|A0A024RCR6|A0A024RCR6_HUMAN,tr|A0A0G2JK23|A0A0G2JK23_HUMAN" 6 2214.0606 2.11 133136 14886 4 2214.060354 554.5224 Large proline-rich protein BAG6 OS=Homo sapiens OX=9606 GN=BAG6 PE=1 SV=2 6.66 2774.9 - 27838 - - - -0.1337 - 0.917 0.112 - 13 1 2 0 -0.0003 19 0 0 0 1.09E+06 5.17E+05 - - - 0.1715 1 221125_WJC_METTL3_EV_vs_WT_F09.14888.14888.3 1.77E-09 Sep-96 K.LVQDVANNTNEEAGDGTTTATVLAR.S "sp|P10809|CH60_HUMAN,tr|C9JL25|C9JL25_HUMAN,tr|A0A7I2V2X6|A0A7I2V2X6_HUMAN,tr|A0A7I2YQK6|A0A7I2YQK6_HUMAN,tr|A0A7I2V599|A0A7I2V599_HUMAN,tr|E7EXB4|E7EXB4_HUMAN,tr|A0A7I2YQ71|A0A7I2YQ71_HUMAN,tr|E7ESH4|E7ESH4_HUMAN,tr|A0A7I2V5M1|A0A7I2V5M1_HUMAN,tr|A0A7I2V5K3|A0A7I2V5K3_HUMAN,tr|A0A7I2V369|A0A7I2V369_HUMAN" 11 2559.2413 1.31 133137 14888 3 2559.245641 854.0877 "60 kDa heat shock protein, mitochondrial OS=Homo sapiens OX=9606 GN=HSPD1 PE=1 SV=2" 3.92 2775.2 - 86363.8 - - - 1.7146 - 2.501 0.709 - 73.9 1 2 0 0.0044 25 0 0 0 1.76E+07 1.34E+07 - - - 8.5524 1 221125_WJC_METTL3_EV_vs_WT_F09.14889.14889.3 7.62E-10 13/96 K.LVQDVANNTNEEAGDGTTTATVLAR[166.11].S "sp|P10809|CH60_HUMAN,tr|C9JL25|C9JL25_HUMAN,tr|A0A7I2V2X6|A0A7I2V2X6_HUMAN,tr|A0A7I2YQK6|A0A7I2YQK6_HUMAN,tr|A0A7I2V599|A0A7I2V599_HUMAN,tr|E7EXB4|E7EXB4_HUMAN,tr|A0A7I2YQ71|A0A7I2YQ71_HUMAN,tr|E7ESH4|E7ESH4_HUMAN,tr|A0A7I2V5M1|A0A7I2V5M1_HUMAN,tr|A0A7I2V5K3|A0A7I2V5K3_HUMAN,tr|A0A7I2V369|A0A7I2V369_HUMAN" 11 2569.2495 1.31 133138 14889 3 2569.25394 857.4238 "60 kDa heat shock protein, mitochondrial OS=Homo sapiens OX=9606 GN=HSPD1 PE=1 SV=2" 3.92 2775.3 - 66657.6 - - - 1.7192 - 2.773 0.583 - 187.3 1 2 0 0.0044 25 0 0 0 1.76E+07 1.34E+07 - - - 7.3851 0.9993 221125_WJC_METTL3_EV_vs_WT_F09.14898.14898.4 0.00262 8/120 K.GIDEDDLLEDKLSGSNNANKR.Q "sp|O75486|SUPT3_HUMAN,tr|A0A1B0GVT7|A0A1B0GVT7_HUMAN,tr|A0A6I8PRV1|A0A6I8PRV1_HUMAN" 3 2302.1037 1.62 133142 14898 4 2302.106187 576.5332 Transcription initiation protein SPT3 homolog OS=Homo sapiens OX=9606 GN=SUPT3H PE=1 SV=3 4.23 2776.7 - 151904 - - - 1.0816 - 2.064 0.389 - 32.9 1 2 1 0.0025 21 0 0 0 7.76E+06 4.79E+06 - - - 2.8508 0.9999 221125_WJC_METTL3_EV_vs_WT_F09.14913.14913.4 1.13E-06 14/120 K.GIDEDDLLEDK[136.11]LSGSNNANK[136.11]R[166.11].Q "sp|O75486|SUPT3_HUMAN,tr|A0A1B0GVT7|A0A1B0GVT7_HUMAN,tr|A0A6I8PRV1|A0A6I8PRV1_HUMAN" 3 2328.1404 1.67 133149 14913 4 2328.140057 583.0424 Transcription initiation protein SPT3 homolog OS=Homo sapiens OX=9606 GN=SUPT3H PE=1 SV=3 4.23 2778.9 - 248686 - - - -0.1332 - 2.861 0.505 - 136.5 1 2 1 -0.0003 21 0 0 0 8.11E+06 4.87E+06 - - - 3.969 0.9998 221125_WJC_METTL3_EV_vs_WT_F09.14943.14943.3 0.000126 7/100 K.NQSPTEAEKPASSSLPSSPPPQLLTR.N "sp|Q99567|NUP88_HUMAN,tr|I3L2W3|I3L2W3_HUMAN" 2 2718.3824 2.54 133167 14943 3 2718.391645 907.1348 Nuclear pore complex protein Nup88 OS=Homo sapiens OX=9606 GN=NUP88 PE=1 SV=2 6.14 2783.3 - 45161.6 - - - 3.3869 - 1.896 0.553 - 35.5 1 2 0 0.0092 26 0 0 0 1.16E+08 4.56E+07 - - - 6.1747 0.9996 221125_WJC_METTL3_EV_vs_WT_F09.14949.14949.4 1.20E-05 15/108 K.VTEGLTDVILYHQPDDKKK.N "sp|O60506|HNRPQ_HUMAN,tr|A0A7I2YQV8|A0A7I2YQV8_HUMAN,tr|A0A7I2YQN2|A0A7I2YQN2_HUMAN,tr|A0A7I2V5Q6|A0A7I2V5Q6_HUMAN,tr|A0A7I2V4Z0|A0A7I2V4Z0_HUMAN,tr|B7Z645|B7Z645_HUMAN,tr|A0A7I2V2F2|A0A7I2V2F2_HUMAN,tr|A0A7I2V346|A0A7I2V346_HUMAN,tr|A0A7I2V309|A0A7I2V309_HUMAN" 9 2198.1583 1.25 133170 14949 4 2198.166105 550.5469 Heterogeneous nuclear ribonucleoprotein Q OS=Homo sapiens OX=9606 GN=SYNCRIP PE=1 SV=2 5.43 2784.1 - 193686 - - - 3.5512 - 2.822 0.556 - 75.8 1 2 1 0.0078 19 0 0 0 7.77E+06 6.23E+06 - - - 4.4142 0.9751 221125_WJC_METTL3_EV_vs_WT_F09.14951.14951.4 0.00231 10/186 D.SPVPTAPTSGGPK[136.11]PSTASAVPELATDPELEK[136.11]K[136.11].L "sp|Q86U44|MTA70_HUMAN,tr|B4E349|B4E349_HUMAN,tr|F5H6D8|F5H6D8_HUMAN,tr|B4DTN4|B4DTN4_HUMAN" 4 3182.6773 0 133172 14951 4 3182.683995 796.6766 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 4.87 2784.4 - 203122 - - - 2.1067 - 2.343 0.411 - 34.5 1 1 0 0.0067 32 0 0 0 2.71E+05 4.41E+08 - - - 3.0586 0.9989 221125_WJC_METTL3_EV_vs_WT_F09.14958.14958.3 0.000952 7/128 K.LASVPAGGAVAVSAAPGSAAPAAGSAPAAAEEK.K "sp|P05387|RLA2_HUMAN,tr|H0YDD8|H0YDD8_HUMAN" 2 2773.4246 1.63 133176 14958 3 2773.433059 925.4822 60S acidic ribosomal protein P2 OS=Homo sapiens OX=9606 GN=RPLP2 PE=1 SV=1 4.53 2785.5 - 47131.3 - - - 3.0367 - 1.456 0.44 - 22.4 1 2 0 0.0084 33 0 0 0 5.00E+06 3.06E+06 - - - 4.3076 0.996 221125_WJC_METTL3_EV_vs_WT_F09.14965.14965.4 9.14E-08 20/144 R.SEAEEAITSFNGHK[136.11]PPGSSEPITVK[136.11].F sp|Q15717|ELAV1_HUMAN 1 2627.305 1.53 133181 14965 4 2628.299016 657.8335 ELAV-like protein 1 OS=Homo sapiens OX=9606 GN=ELAVL1 PE=1 SV=2 4.9 2786.4 - 1.32E+06 - - - 378.3497 - 3.342 0.549 - 189 1 2 0 0.994 25 0 0 0 3.20E+08 2.10E+08 - - - 4.113 1 221125_WJC_METTL3_EV_vs_WT_F09.14971.14971.3 2.52E-08 11/128 R.GGGGYGGSGDGYNGFGNDGGYGGGGPGYSGGSR.G sp|P09651|ROA1_HUMAN 1 2873.1298 1.71 133184 14971 3 2873.137514 958.7172 Heterogeneous nuclear ribonucleoprotein A1 OS=Homo sapiens OX=9606 GN=HNRNPA1 PE=1 SV=5 4.21 2787.2 - 73952.4 - - - 2.6831 - 2.451 0.811 - 95.5 1 2 0 0.0077 33 0 0 0 1.87E+06 1.09E+06 - - - 9.6422 1 221125_WJC_METTL3_EV_vs_WT_F09.14974.14974.3 8.92E-09 17/64 K.GYPHLC[160.03]SIC[160.03]DLPVHSNK.E "sp|P43243|MATR3_HUMAN,tr|A8MXP9|A8MXP9_HUMAN,tr|D6R991|D6R991_HUMAN,tr|A0A0R4J2E8|A0A0R4J2E8_HUMAN,tr|H0Y8T4|H0Y8T4_HUMAN,tr|D6REM6|D6REM6_HUMAN" 6 1995.9295 0.91 133185 14974 3 1995.934665 666.3171 Matrin-3 OS=Homo sapiens OX=9606 GN=MATR3 PE=1 SV=2 6.9 2787.7 - 247437 - - - 2.5868 - 3.262 0.689 - 367.5 1 2 0 0.0052 17 0 0 0 7.61E+06 8.37E+06 - - - 9.2072 0.9998 221125_WJC_METTL3_EV_vs_WT_F09.14978.14978.3 2.69E-07 8/100 K.NQSPTEAEK[136.11]PASSSLPSSPPPQLLTR[166.11].N "sp|Q99567|NUP88_HUMAN,tr|I3L2W3|I3L2W3_HUMAN" 2 2736.4049 2.52 133189 14978 3 2736.411313 913.1422 Nuclear pore complex protein Nup88 OS=Homo sapiens OX=9606 GN=NUP88 PE=1 SV=2 6.14 2788.2 - 81626.6 - - - 2.3407 - 2.117 0.469 - 60.1 1 2 0 0.0064 26 0 0 0 1.18E+08 4.69E+07 - - - 5.4926 0.9863 221125_WJC_METTL3_EV_vs_WT_F09.14983.14983.4 1.73E-05 16/144 R.SEAEEAITSFNGHKPPGSSEPITVK.F sp|Q15717|ELAV1_HUMAN 1 2611.2766 1.53 133192 14983 4 2612.271379 653.8264 ELAV-like protein 1 OS=Homo sapiens OX=9606 GN=ELAVL1 PE=1 SV=2 4.9 2788.9 - 898236 - - - 380.9642 - 2.618 0.442 - 114.7 1 2 0 0.9948 25 0 0 0 3.23E+08 2.12E+08 - - - 3.1038 0.9987 221125_WJC_METTL3_EV_vs_WT_F09.14986.14986.3 0.0264 Jun-56 R.STSHK[136.11]PDEIYGMIER[166.11].L sp|Q86U44|MTA70_HUMAN 1 1779.8581 -1 133195 14986 3 1779.86045 594.2933 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 5.42 2789.3 - 95778.8 - - - 1.3462 - 1.228 0.381 - 54 1 2 0 0.0024 15 0 0 0 0.00E+00 0.00E+00 - - - 3.323 1 221125_WJC_METTL3_EV_vs_WT_F09.14991.14991.3 1.14E-06 12/128 R.GGGGYGGSGDGYNGFGNDGGYGGGGPGYSGGSR[166.11].G sp|P09651|ROA1_HUMAN 1 2883.1381 1.71 133198 14991 3 2883.138955 962.0533 Heterogeneous nuclear ribonucleoprotein A1 OS=Homo sapiens OX=9606 GN=HNRNPA1 PE=1 SV=5 4.21 2790 - 98157.8 - - - 0.3052 - 2.597 0.77 - 107.4 1 2 0 0.0009 33 0 0 0 1.87E+06 1.09E+06 - - - 9.3201 1 221125_WJC_METTL3_EV_vs_WT_F09.14997.14997.3 8.56E-13 26/84 K.DHTPSQELALTQSVGGDSSADR[166.11].L "sp|Q86U44|MTA70_HUMAN,tr|H0YFV6|H0YFV6_HUMAN" 2 2280.0494 0.02 133203 14997 3 2280.048499 761.0237 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 4.22 2790.9 - 863833 - - - -0.3807 - 4.61 0.725 - 744.7 1 2 0 -0.0009 22 0 0 0 5.58E+06 2.85E+08 - - - 10.246 1 221125_WJC_METTL3_EV_vs_WT_F09.15001.15001.3 2.32E-07 Oct-64 K.GYPHLC[160.03]SIC[160.03]DLPVHSNK[136.11].E "sp|P43243|MATR3_HUMAN,tr|A8MXP9|A8MXP9_HUMAN,tr|D6R991|D6R991_HUMAN,tr|A0A0R4J2E8|A0A0R4J2E8_HUMAN,tr|H0Y8T4|H0Y8T4_HUMAN,tr|D6REM6|D6REM6_HUMAN" 6 2003.9437 1.39 133205 15001 3 2003.945823 668.9885 Matrin-3 OS=Homo sapiens OX=9606 GN=MATR3 PE=1 SV=2 6.9 2791.5 - 118586 - - - 1.0584 - 1.977 0.606 - 114.9 1 2 0 0.0021 17 0 0 0 8.99E+06 6.45E+06 - - - 7.0176 0.9999 221125_WJC_METTL3_EV_vs_WT_F09.15008.15008.4 0.000765 12/114 K.R[166.11]GLLQDDAHPTLVTYADHSK[136.11].L "sp|Q86U44|MTA70_HUMAN,tr|F5H6D8|F5H6D8_HUMAN,tr|H0YFV6|H0YFV6_HUMAN,tr|B4DTN4|B4DTN4_HUMAN" 4 2254.1461 0.01 133210 15008 4 2254.146566 564.5438 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 5.99 2792.5 - 112214 - - - 0.2001 - 2.559 0.436 - 104.9 1 2 0 0.0005 20 0 0 0 1.30E+05 1.34E+07 - - - 3.335 0.9893 221125_WJC_METTL3_EV_vs_WT_F09.15014.15014.3 0.0002 10/124 D.SPVPTAPTSGGPK[136.11]PSTASAVPELATDPELEK[136.11]K[136.11].L "sp|Q86U44|MTA70_HUMAN,tr|B4E349|B4E349_HUMAN,tr|F5H6D8|F5H6D8_HUMAN,tr|B4DTN4|B4DTN4_HUMAN" 4 3182.6773 0.001 133214 15014 3 3182.676723 1061.8997 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 4.87 2793.3 - 151718 - - - -0.1782 - 2.16 0.435 - 44.7 1 1 0 -0.0006 32 0 0 0 0.00E+00 1.17E+07 - - - 5.1614 0.9992 221125_WJC_METTL3_EV_vs_WT_F09.15024.15024.4 0.000678 7/114 K.HAAENPGKYNILGTNTIMDK.M "sp|Q00839|HNRPU_HUMAN,tr|A0A1W2PQL0|A0A1W2PQL0_HUMAN,tr|A0A1W2PPL4|A0A1W2PPL4_HUMAN,tr|A0A1W2PQ74|A0A1W2PQ74_HUMAN,tr|Q5RI18|Q5RI18_HUMAN,tr|A0A1W2PP35|A0A1W2PP35_HUMAN,tr|A0A1W2PPS1|A0A1W2PPS1_HUMAN,tr|A0A1W2PRZ7|A0A1W2PRZ7_HUMAN,tr|A0A1W2PPH7|A0A1W2PPH7_HUMAN,tr|A0A1W2PQD4|A0A1W2PQD4_HUMAN,tr|A0A1W2PP34|A0A1W2PP34_HUMAN,tr|A0A1X7SBS1|A0A1X7SBS1_HUMAN" 12 2186.079 1.11 133219 15024 4 2186.082049 547.527 Heterogeneous nuclear ribonucleoprotein U OS=Homo sapiens OX=9606 GN=HNRNPU PE=1 SV=6 6.75 2794.7 - 64083.7 - - - 1.3934 - 1.835 0.394 - 32.5 1 2 1 0.003 20 0 0 0 2.01E+07 1.81E+07 - - - 2.8575 0.9865 221125_WJC_METTL3_EV_vs_WT_F09.15027.15027.4 0.000197 9/114 K.HAAENPGK[136.11]YNILGTNTIMDK[136.11].M "sp|Q00839|HNRPU_HUMAN,tr|A0A1W2PQL0|A0A1W2PQL0_HUMAN,tr|A0A1W2PPL4|A0A1W2PPL4_HUMAN,tr|A0A1W2PQ74|A0A1W2PQ74_HUMAN,tr|Q5RI18|Q5RI18_HUMAN,tr|A0A1W2PP35|A0A1W2PP35_HUMAN,tr|A0A1W2PPS1|A0A1W2PPS1_HUMAN,tr|A0A1W2PRZ7|A0A1W2PRZ7_HUMAN,tr|A0A1W2PPH7|A0A1W2PPH7_HUMAN,tr|A0A1W2PQD4|A0A1W2PQD4_HUMAN,tr|A0A1W2PP34|A0A1W2PP34_HUMAN,tr|A0A1X7SBS1|A0A1X7SBS1_HUMAN" 12 2202.1074 1.11 133222 15027 4 2203.116964 551.5341 Heterogeneous nuclear ribonucleoprotein U OS=Homo sapiens OX=9606 GN=HNRNPU PE=1 SV=6 6.75 2795.1 - 116961 - - - 458.4522 - 1.658 0.541 - 29.4 1 2 1 1.0096 20 0 0 0 2.01E+07 1.81E+07 - - - 3.8243 0.9999 221125_WJC_METTL3_EV_vs_WT_F09.15032.15032.3 0.00822 Jul-68 R.DQEKPYFSSFDSGASTNR.K "sp|O15504|NUP42_HUMAN,tr|B4DT96|B4DT96_HUMAN,tr|C9JYA1|C9JYA1_HUMAN" 3 2034.8919 3.11 133225 15032 3 2034.894511 679.3046 Nucleoporin NUP42 OS=Homo sapiens OX=9606 GN=NUP42 PE=1 SV=1 4.56 2795.8 - 127284 - - - 1.2767 - 1.889 0.444 - 52.5 1 2 0 0.0026 18 0 0 0 3.62E+06 1.16E+06 - - - 5.0733 0.9787 221125_WJC_METTL3_EV_vs_WT_F09.15034.15034.3 0.00512 Aug-64 L.LQDDAHPTLVTYADHSK[136.11].L "sp|Q86U44|MTA70_HUMAN,tr|F5H6D8|F5H6D8_HUMAN,tr|H0YFV6|H0YFV6_HUMAN,tr|B4DTN4|B4DTN4_HUMAN" 4 1917.9312 0.01 133227 15034 3 1917.929924 640.3177 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 5.13 2796.1 - 107942 - - - -0.6684 - 1.682 0.42 - 82.7 1 1 0 -0.0013 17 0 0 0 8.36E+05 8.50E+07 - - - 4.5359 0.9998 221125_WJC_METTL3_EV_vs_WT_F09.15037.15037.4 0.0122 Jul-96 R.R[166.11]APEEELPPLDPEEIR[166.11]K[136.11].R "sp|Q8IY67|RAVR1_HUMAN,tr|K7EKR9|K7EKR9_HUMAN,tr|E9PAU2|E9PAU2_HUMAN,tr|A0A087WZ13|A0A087WZ13_HUMAN" 4 2045.0788 1.78 133228 15037 4 2045.078477 512.277 Ribonucleoprotein PTB-binding 1 OS=Homo sapiens OX=9606 GN=RAVER1 PE=1 SV=1 4.42 2796.5 - 62933.9 - - - -0.1384 - 1.697 0.394 - 44.8 1 2 0 -0.0003 17 0 0 0 5.18E+06 2.92E+06 - - - 2.8389 0.9858 221125_WJC_METTL3_EV_vs_WT_F09.15044.15044.2 0.784 16-Jun K.IGPLGLSPK.K sp|P30050|RL12_HUMAN 1 880.5382 8.96 133232 15044 2 880.538516 441.2764 60S ribosomal protein L12 OS=Homo sapiens OX=9606 GN=RPL12 PE=1 SV=1 8.75 2797.4 - 90132.5 - - - 0.3555 - 1.05 0.167 - 83.9 1 2 0 0.0003 9 0 0 0 1.24E+07 1.38E+06 - - - 0.4155 0.8985 221125_WJC_METTL3_EV_vs_WT_F09.15048.15048.4 0.00757 Jul-96 L.LQDDAHPTLVTYADHSK[136.11].L "sp|Q86U44|MTA70_HUMAN,tr|F5H6D8|F5H6D8_HUMAN,tr|H0YFV6|H0YFV6_HUMAN,tr|B4DTN4|B4DTN4_HUMAN" 4 1917.9312 0.02 133234 15048 4 1917.927308 480.4901 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 5.13 2798 - 68721.9 - - - -2.0324 - 1.288 0.338 - 36.9 1 1 0 -0.0039 17 0 0 0 3.26E+05 1.85E+07 - - - 2.2547 0.9999 221125_WJC_METTL3_EV_vs_WT_F09.15056.15056.3 1.87E-06 Jul-76 K.HAAENPGKYNILGTNTIMDK.M "sp|Q00839|HNRPU_HUMAN,tr|A0A1W2PQL0|A0A1W2PQL0_HUMAN,tr|A0A1W2PPL4|A0A1W2PPL4_HUMAN,tr|A0A1W2PQ74|A0A1W2PQ74_HUMAN,tr|Q5RI18|Q5RI18_HUMAN,tr|A0A1W2PP35|A0A1W2PP35_HUMAN,tr|A0A1W2PPS1|A0A1W2PPS1_HUMAN,tr|A0A1W2PRZ7|A0A1W2PRZ7_HUMAN,tr|A0A1W2PPH7|A0A1W2PPH7_HUMAN,tr|A0A1W2PQD4|A0A1W2PQD4_HUMAN,tr|A0A1W2PP34|A0A1W2PP34_HUMAN,tr|A0A1X7SBS1|A0A1X7SBS1_HUMAN" 12 2186.079 1.07 133236 15056 3 2186.076335 729.7003 Heterogeneous nuclear ribonucleoprotein U OS=Homo sapiens OX=9606 GN=HNRNPU PE=1 SV=6 6.75 2799.2 - 157996 - - - -1.2204 - 2.031 0.572 - 41.2 1 2 1 -0.0027 20 0 0 0 1.10E+07 1.02E+07 - - - 6.6354 0.9943 221125_WJC_METTL3_EV_vs_WT_F09.15057.15057.4 0.0503 6/138 K.QTAISQPASGNTFSHHSMVSMLGK.G "sp|Q14157|UBP2L_HUMAN,tr|F8W726|F8W726_HUMAN" 2 2515.1948 1.98 133237 15057 4 2515.195854 629.806 Ubiquitin-associated protein 2-like OS=Homo sapiens OX=9606 GN=UBAP2L PE=1 SV=2 8.76 2799.3 - 197254 - - - 0.4282 - 1.264 0.238 - 11.2 1 2 0 0.0011 24 0 0 0 2.13E+07 1.08E+07 - - - 1.3724 0.9999 221125_WJC_METTL3_EV_vs_WT_F09.15069.15069.3 3.36E-05 Aug-52 K.K[136.11]GPGEVAGTVTGQK[136.11].R "sp|Q86U44|MTA70_HUMAN,tr|F5H6D8|F5H6D8_HUMAN,tr|H0YFV6|H0YFV6_HUMAN,tr|B4DTN4|B4DTN4_HUMAN" 4 1343.738 0.02 133244 15069 3 1343.735747 448.9199 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 8.59 2800.8 - 156776 - - - -1.661 - 1.934 0.509 - 114.9 1 2 0 -0.0022 14 0 0 0 2.42E+05 1.16E+07 - - - 5.9671 0.9829 221125_WJC_METTL3_EV_vs_WT_F09.15073.15073.2 0.00304 Jun-36 R.GLLQDDAHPTLVTYADHSK[136.11].L "sp|Q86U44|MTA70_HUMAN,tr|F5H6D8|F5H6D8_HUMAN,tr|H0YFV6|H0YFV6_HUMAN,tr|B4DTN4|B4DTN4_HUMAN" 4 2088.0367 0.001 133246 15073 2 2088.023971 1045.0256 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 5.13 2801.4 - 105182 - - - -6.112 - 1.36 0.464 - 58.1 1 2 0 -0.0128 19 0 0 0 0.00E+00 1.03E+07 - - - 3.2201 0.9944 221125_WJC_METTL3_EV_vs_WT_F09.15075.15075.3 3.62E-05 Aug-56 Q.DDAHPTLVTYADHSK[136.11].L "sp|Q86U44|MTA70_HUMAN,tr|F5H6D8|F5H6D8_HUMAN,tr|H0YFV6|H0YFV6_HUMAN,tr|B4DTN4|B4DTN4_HUMAN" 4 1676.7886 0.03 133247 15075 3 1676.78763 559.9368 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 5.13 2801.6 - 54922.9 - - - -0.557 - 1.68 0.532 - 67 1 1 0 -0.0009 15 0 0 0 2.74E+05 9.86E+06 - - - 5.8247 0.9999 221125_WJC_METTL3_EV_vs_WT_F09.15081.15081.3 3.92E-08 Sep-76 K.HAAENPGK[136.11]YNILGTNTIMDK[136.11].M "sp|Q00839|HNRPU_HUMAN,tr|A0A1W2PQL0|A0A1W2PQL0_HUMAN,tr|A0A1W2PPL4|A0A1W2PPL4_HUMAN,tr|A0A1W2PQ74|A0A1W2PQ74_HUMAN,tr|Q5RI18|Q5RI18_HUMAN,tr|A0A1W2PP35|A0A1W2PP35_HUMAN,tr|A0A1W2PPS1|A0A1W2PPS1_HUMAN,tr|A0A1W2PRZ7|A0A1W2PRZ7_HUMAN,tr|A0A1W2PPH7|A0A1W2PPH7_HUMAN,tr|A0A1W2PQD4|A0A1W2PQD4_HUMAN,tr|A0A1W2PP34|A0A1W2PP34_HUMAN,tr|A0A1X7SBS1|A0A1X7SBS1_HUMAN" 12 2202.1074 1.08 133250 15081 3 2202.104854 735.0431 Heterogeneous nuclear ribonucleoprotein U OS=Homo sapiens OX=9606 GN=HNRNPU PE=1 SV=6 6.75 2802.2 - 290672 - - - -1.1575 - 2.34 0.602 - 64.9 1 2 1 -0.0025 20 0 0 0 1.10E+07 1.02E+07 - - - 7.3135 0.9999 221125_WJC_METTL3_EV_vs_WT_F09.15083.15083.4 0.00452 Oct-96 K.GYPHLC[160.03]SIC[160.03]DLPVHSNK.E "sp|P43243|MATR3_HUMAN,tr|A8MXP9|A8MXP9_HUMAN,tr|D6R991|D6R991_HUMAN,tr|A0A0R4J2E8|A0A0R4J2E8_HUMAN,tr|H0Y8T4|H0Y8T4_HUMAN,tr|D6REM6|D6REM6_HUMAN" 6 1995.9295 1.56 133251 15083 4 1995.926029 499.9897 Matrin-3 OS=Homo sapiens OX=9606 GN=MATR3 PE=1 SV=2 6.9 2802.5 - 152729 - - - -1.74 - 1.973 0.481 - 54.9 1 2 0 -0.0035 17 0 0 0 8.73E+06 5.60E+06 - - - 3.6476 0.9945 221125_WJC_METTL3_EV_vs_WT_F09.15085.15085.3 4.51E-06 15/60 L.QDDAHPTLVTYADHSK[136.11].L "sp|Q86U44|MTA70_HUMAN,tr|F5H6D8|F5H6D8_HUMAN,tr|H0YFV6|H0YFV6_HUMAN,tr|B4DTN4|B4DTN4_HUMAN" 4 1804.8471 0.03 133252 15085 3 1804.842837 602.623 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 5.13 2802.7 - 603336 - - - -2.3852 - 2.714 0.522 - 338.5 1 1 0 -0.0043 16 0 0 0 1.44E+06 4.68E+07 - - - 6.9204 1 221125_WJC_METTL3_EV_vs_WT_F09.15114.15114.2 1.33E-08 30-Dec L.QDDAHPTLVTYADHSK[136.11].L "sp|Q86U44|MTA70_HUMAN,tr|F5H6D8|F5H6D8_HUMAN,tr|H0YFV6|H0YFV6_HUMAN,tr|B4DTN4|B4DTN4_HUMAN" 4 1804.8471 0.001 133261 15114 2 1804.836225 903.4308 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 5.13 2806.9 - 0 - - - -6.0487 - 2.448 0.635 - 300.4 1 1 0 -0.0109 16 0 0 0 0.00E+00 1.57E+06 - - - 5.9287 0.9997 221125_WJC_METTL3_EV_vs_WT_F09.15121.15121.4 0.000836 Jul-96 R.RAPEEELPPLDPEEIRK.R "sp|Q8IY67|RAVR1_HUMAN,tr|K7EKR9|K7EKR9_HUMAN,tr|E9PAU2|E9PAU2_HUMAN,tr|A0A087WZ13|A0A087WZ13_HUMAN" 4 2017.048 0.9 133262 15121 4 2017.041655 505.2693 Ribonucleoprotein PTB-binding 1 OS=Homo sapiens OX=9606 GN=RAVER1 PE=1 SV=1 4.42 2808 - 197059 - - - -3.1556 - 1.809 0.433 - 19.6 1 2 0 -0.0064 17 0 0 0 6.43E+06 7.13E+06 - - - 3.1989 1 221125_WJC_METTL3_EV_vs_WT_F09.15131.15131.4 1.41E-06 8/150 K.NQSPTEAEKPASSSLPSSPPPQLLTR.N "sp|Q99567|NUP88_HUMAN,tr|I3L2W3|I3L2W3_HUMAN" 2 2718.3824 3.08 133267 15131 4 2718.384704 680.6029 Nuclear pore complex protein Nup88 OS=Homo sapiens OX=9606 GN=NUP88 PE=1 SV=2 6.14 2809.2 - 226038 - - - 0.8336 - 2.263 0.574 - 44.5 1 2 0 0.0023 26 0 0 0 1.12E+07 3.63E+06 - - - 4.4791 0.9998 221125_WJC_METTL3_EV_vs_WT_F09.15138.15138.4 2.89E-07 14/144 K.VGAVDADKHHSLGGQYGVQGFPTIK.L sp|Q15084|PDIA6_HUMAN 1 2580.3085 1.33 133271 15138 4 2580.303952 646.0844 Protein disulfide-isomerase A6 OS=Homo sapiens OX=9606 GN=PDIA6 PE=1 SV=1 6.89 2810.2 - 381582 - - - -1.7568 - 2.453 0.501 - 122.8 1 2 1 -0.0045 25 0 0 0 2.66E+07 2.00E+07 - - - 3.8709 0.9999 221125_WJC_METTL3_EV_vs_WT_F09.15145.15145.4 2.13E-05 11/144 K.VGAVDADK[136.11]HHSLGGQYGVQGFPTIK[136.11].L sp|Q15084|PDIA6_HUMAN 1 2596.3369 1.33 133273 15145 4 2596.337048 650.0915 Protein disulfide-isomerase A6 OS=Homo sapiens OX=9606 GN=PDIA6 PE=1 SV=1 6.89 2811.2 - 360867 - - - 0.0628 - 2.269 0.531 - 55.8 1 2 1 0.0002 25 0 0 0 2.66E+07 2.00E+07 - - - 4.1084 1 221125_WJC_METTL3_EV_vs_WT_F09.15150.15150.3 4.07E-07 Oct-84 K.DHTPSQELALTQSVGGDSSADR.L "sp|Q86U44|MTA70_HUMAN,tr|H0YFV6|H0YFV6_HUMAN" 2 2270.0411 0.02 133276 15150 3 2270.039662 757.6876 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 4.22 2811.8 - 116334 - - - -0.6321 - 2.406 0.48 - 77.1 1 2 0 -0.0014 22 0 0 0 4.54E+06 2.51E+08 - - - 5.9726 0.9975 221125_WJC_METTL3_EV_vs_WT_F09.15152.15152.4 0.00637 6/114 K.FVIKRPELLTHSTTEVTQPR.T "sp|P78347|GTF2I_HUMAN,tr|A0A494C0Q7|A0A494C0Q7_HUMAN,tr|A0A494C1K3|A0A494C1K3_HUMAN" 3 2351.2961 1.43 133278 15152 4 2351.292955 588.8313 General transcription factor II-I OS=Homo sapiens OX=9606 GN=GTF2I PE=1 SV=2 8.75 2812.1 - 104386 - - - -1.3503 - 1.286 0.339 - 18.1 1 2 1 -0.0032 20 0 0 0 3.93E+06 2.75E+06 - - - 2.2599 1 221125_WJC_METTL3_EV_vs_WT_F09.15158.15158.3 2.77E-11 13/108 R.VSGLQGSDALNIQQNQTSGGSLQAGQQK.E sp|P08047|SP1_HUMAN 1 2813.3904 1.19 133282 15158 3 2813.384425 938.8041 Transcription factor Sp1 OS=Homo sapiens OX=9606 GN=SP1 PE=1 SV=3 5.81 2812.9 - 164212 - - - -2.1156 - 3.213 0.637 - 163.7 1 2 0 -0.006 28 0 0 0 3.19E+06 2.67E+06 - - - 8.3256 1 221125_WJC_METTL3_EV_vs_WT_F09.15159.15159.3 6.06E-06 11/108 R.VSGLQGSDALNIQQNQTSGGSLQAGQQK[136.11].E sp|P08047|SP1_HUMAN 1 2821.4046 1.19 133283 15159 3 2821.398853 941.4755 Transcription factor Sp1 OS=Homo sapiens OX=9606 GN=SP1 PE=1 SV=3 5.81 2813 - 138822 - - - -2.0288 - 3.059 0.596 - 90.6 1 2 0 -0.0057 28 0 0 0 3.19E+06 2.67E+06 - - - 7.7555 0.9997 221125_WJC_METTL3_EV_vs_WT_F09.15162.15162.3 0.000574 Jun-56 R.GPSLNPVLDYDHGSR.S "sp|P43243|MATR3_HUMAN,tr|A8MXP9|A8MXP9_HUMAN,tr|D6R991|D6R991_HUMAN,tr|A0A0R4J2E8|A0A0R4J2E8_HUMAN,tr|D6REM6|D6REM6_HUMAN" 5 1625.7798 0.98 133286 15162 3 1625.777103 542.9339 Matrin-3 OS=Homo sapiens OX=9606 GN=MATR3 PE=1 SV=2 5.21 2813.4 - 97360.3 - - - -1.6491 - 1.411 0.464 - 42.5 1 2 0 -0.0027 15 0 0 0 2.97E+06 3.03E+06 - - - 4.6108 1 221125_WJC_METTL3_EV_vs_WT_F09.15165.15165.3 1.69E-13 21/100 K.NQSPTEAEKPASSSLPSSPPPQLLTR.N "sp|Q99567|NUP88_HUMAN,tr|I3L2W3|I3L2W3_HUMAN" 2 2718.3824 2.53 133287 15165 3 2718.383184 907.1348 Nuclear pore complex protein Nup88 OS=Homo sapiens OX=9606 GN=NUP88 PE=1 SV=2 6.14 2813.8 - 677933 - - - 0.2744 - 3.841 0.703 - 348.8 1 2 0 0.0007 26 0 0 0 1.18E+08 4.68E+07 - - - 9.4736 0.9897 221125_WJC_METTL3_EV_vs_WT_F09.15169.15169.3 0.0376 May-72 R.VIHLSNLPHSGYSDSAVLK[136.11].L "sp|P43243|MATR3_HUMAN,tr|B3KM87|B3KM87_HUMAN,tr|A8MXP9|A8MXP9_HUMAN,tr|D6RBK5|D6RBK5_HUMAN,tr|A0A0R4J2E8|A0A0R4J2E8_HUMAN,tr|H0Y8T4|H0Y8T4_HUMAN,tr|D6REM6|D6REM6_HUMAN" 7 2044.0833 2.18 133291 15169 3 2044.085003 682.3684 Matrin-3 OS=Homo sapiens OX=9606 GN=MATR3 PE=1 SV=2 6.89 2814.3 - 86533.3 - - - 0.838 - 1.298 0.248 - 28.2 2 2 0 0.0017 19 0 0 0 2.73E+07 1.25E+07 - - - 1.806 0.9999 221125_WJC_METTL3_EV_vs_WT_F09.15173.15173.4 0.000253 14/108 R.VIHLSNLPHSGYSDSAVLK.L "sp|P43243|MATR3_HUMAN,tr|B3KM87|B3KM87_HUMAN,tr|A8MXP9|A8MXP9_HUMAN,tr|D6RBK5|D6RBK5_HUMAN,tr|A0A0R4J2E8|A0A0R4J2E8_HUMAN,tr|H0Y8T4|H0Y8T4_HUMAN,tr|D6REM6|D6REM6_HUMAN" 7 2036.0691 1.39 133293 15173 4 2036.072844 510.0245 Matrin-3 OS=Homo sapiens OX=9606 GN=MATR3 PE=1 SV=2 6.89 2814.8 - 495962 - - - 1.8437 - 2.864 0.478 - 166.7 1 2 0 0.0038 19 0 0 0 4.24E+07 3.06E+07 - - - 3.7414 1 221125_WJC_METTL3_EV_vs_WT_F09.15175.15175.3 1.95E-09 21/72 R.GLLQDDAHPTLVTYADHSK[136.11].L "sp|Q86U44|MTA70_HUMAN,tr|F5H6D8|F5H6D8_HUMAN,tr|H0YFV6|H0YFV6_HUMAN,tr|B4DTN4|B4DTN4_HUMAN" 4 2088.0367 0.02 133294 15175 3 2088.037504 697.0195 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 5.13 2815 - 3.25E+06 - - - 0.3692 - 3.498 0.642 - 430.9 1 2 0 0.0008 19 0 0 0 2.59E+07 1.72E+09 - - - 8.7738 0.8859 221125_WJC_METTL3_EV_vs_WT_F09.15177.15177.4 0.0841 6/126 R.VTELFMDNKNELDQC[160.03]KSDLQNK.T "sp|P52732|KIF11_HUMAN,tr|A0A7I2YQY4|A0A7I2YQY4_HUMAN,tr|A0A7I2V3A9|A0A7I2V3A9_HUMAN,tr|A0A7I2V3V3|A0A7I2V3V3_HUMAN" 4 2668.2473 7.34 133296 15177 4 2668.255662 668.0691 Kinesin-like protein KIF11 OS=Homo sapiens OX=9606 GN=KIF11 PE=1 SV=2 4.44 2815.3 - 125989 - - - 3.1463 - 1.642 0.208 - 20.8 1 2 2 0.0084 22 0 0 0 2.63E+06 3.59E+05 - - - 1.1964 0.9998 221125_WJC_METTL3_EV_vs_WT_F09.15178.15178.3 0.000771 Jul-96 K.QGSLINSLKPSGPTPASGQLSSGDK.A "sp|P35658|NU214_HUMAN,tr|A0A0A0MSW3|A0A0A0MSW3_HUMAN,tr|A0A494C1F2|A0A494C1F2_HUMAN,tr|A0A494C104|A0A494C104_HUMAN,tr|H0Y837|H0Y837_HUMAN" 5 2425.2449 2.33 133297 15178 3 2425.24806 809.4222 Nuclear pore complex protein Nup214 OS=Homo sapiens OX=9606 GN=NUP214 PE=1 SV=2 8.59 2815.4 - 79931.5 - - - 1.3104 - 1.735 0.435 - 39.2 1 2 0 0.0032 25 0 0 0 2.87E+07 1.23E+07 - - - 4.6566 0.9909 221125_WJC_METTL3_EV_vs_WT_F09.15180.15180.2 0.282 22-Apr R.INVYYNEATGGK.Y sp|P68371|TBB4B_HUMAN 1 1327.6408 4.84 133299 15180 2 1327.640966 664.8277 Tubulin beta-4B chain OS=Homo sapiens OX=9606 GN=TUBB4B PE=1 SV=1 6 2815.7 - 60541.9 - - - 0.1017 - 0.976 0.231 - 46.4 1 2 0 0.0001 12 0 0 0 1.52E+06 3.14E+05 - - - 0.6832 1 221125_WJC_METTL3_EV_vs_WT_F09.15195.15195.3 3.53E-10 20/92 R.TSFSPC[160.03]VPQC[160.03]QTQGSYGSFTEQHR.S sp|Q5T749|KPRP_HUMAN 1 2788.197 999 133308 15195 3 2788.195449 930.4063 Keratinocyte proline-rich protein OS=Homo sapiens OX=9606 GN=KPRP PE=1 SV=1 6.41 2817.8 - 170761 - - - -0.543 - 3.674 0.734 - 319.1 1 2 0 -0.0015 24 0 0 0 2.12E+07 0.00E+00 - - - 9.7453 1 221125_WJC_METTL3_EV_vs_WT_F09.15196.15196.3 1.11E-07 Dec-96 K.QGSLINSLK[136.11]PSGPTPASGQLSSGDK[136.11].A "sp|P35658|NU214_HUMAN,tr|A0A0A0MSW3|A0A0A0MSW3_HUMAN,tr|A0A494C1F2|A0A494C1F2_HUMAN,tr|A0A494C104|A0A494C104_HUMAN,tr|H0Y837|H0Y837_HUMAN" 5 2441.2733 2.32 133309 15196 3 2441.272218 814.765 Nuclear pore complex protein Nup214 OS=Homo sapiens OX=9606 GN=NUP214 PE=1 SV=2 8.59 2817.9 - 117389 - - - -0.4358 - 2.627 0.606 - 101.5 1 2 0 -0.0011 25 0 0 0 2.86E+07 1.23E+07 - - - 7.5181 1 221125_WJC_METTL3_EV_vs_WT_F09.15197.15197.4 5.09E-05 10/108 R.GLLQDDAHPTLVTYADHSK[136.11].L "sp|Q86U44|MTA70_HUMAN,tr|F5H6D8|F5H6D8_HUMAN,tr|H0YFV6|H0YFV6_HUMAN,tr|B4DTN4|B4DTN4_HUMAN" 4 2088.0367 0.02 133310 15197 4 2088.039405 523.0165 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 5.13 2818 - 2.70E+06 - - - 1.2797 - 2.329 0.545 - 97.4 1 2 0 0.0027 19 0 0 0 8.74E+07 3.54E+09 - - - 4.2549 1 221125_WJC_METTL3_EV_vs_WT_F09.15198.15198.3 1.87E-09 14/80 K.TSDAPYDSADDWSEHISSSGK.K "sp|Q9BTA9|WAC_HUMAN,tr|A0A494C0B7|A0A494C0B7_HUMAN,tr|A0A0A0MRT2|A0A0A0MRT2_HUMAN,tr|A0A494C0C1|A0A494C0C1_HUMAN,tr|A0A494C0S5|A0A494C0S5_HUMAN,tr|A0A0A0MSR1|A0A0A0MSR1_HUMAN,tr|J3QTA0|J3QTA0_HUMAN,tr|C9JVK6|C9JVK6_HUMAN" 8 2253.9298 2.59 133311 15198 3 2253.935984 752.3172 WW domain-containing adapter protein with coiled-coil OS=Homo sapiens OX=9606 GN=WAC PE=1 SV=3 4.03 2818.1 - 128779 - - - 2.737 - 2.908 0.752 - 203.3 1 2 0 0.0062 21 0 0 0 3.67E+06 1.42E+06 - - - 9.4815 0.9996 221125_WJC_METTL3_EV_vs_WT_F09.15199.15199.4 0.000109 11/138 K.K[136.11]PQDLAHTGISSGLIAGSSIQNPK[136.11].V sp|Q6ZU65|UBN2_HUMAN 1 2434.3151 1.38 133312 15199 4 2434.315883 609.586 Ubinuclein-2 OS=Homo sapiens OX=9606 GN=UBN2 PE=1 SV=2 8.6 2818.2 - 112921 - - - 0.327 - 1.749 0.352 - 52.9 1 2 0 0.0008 24 0 0 0 1.22E+07 8.80E+06 - - - 2.469 0.9999 221125_WJC_METTL3_EV_vs_WT_F09.15202.15202.3 5.16E-07 10/100 K.NQSPTEAEK[136.11]PASSSLPSSPPPQLLTR[166.11].N "sp|Q99567|NUP88_HUMAN,tr|I3L2W3|I3L2W3_HUMAN" 2 2736.4049 2.51 133314 15202 3 2736.412781 913.1422 Nuclear pore complex protein Nup88 OS=Homo sapiens OX=9606 GN=NUP88 PE=1 SV=2 6.14 2818.6 - 153276 - - - 2.8771 - 2.407 0.535 - 69.3 1 2 0 0.0079 26 0 0 0 1.18E+08 4.69E+07 - - - 6.5234 1 221125_WJC_METTL3_EV_vs_WT_F09.15209.15209.3 1.01E-08 Dec-60 K.KQC[160.03]ANLQAAIADAEQR.G "sp|P04259|K2C6B_HUMAN,sp|P02538|K2C6A_HUMAN" 2 1785.8792 12.42 133318 15209 3 1785.883133 596.3003 "Keratin, type II cytoskeletal 6B OS=Homo sapiens OX=9606 GN=KRT6B PE=1 SV=5" 6.06 2819.5 - 125650 - - - 2.2129 - 2.82 0.599 - 162.7 1 2 0 0.004 16 0 0 0 4.11E+06 3.31E+05 - - - 7.8773 1 221125_WJC_METTL3_EV_vs_WT_F09.15212.15212.3 1.62E-06 Sep-80 K.TSDAPYDSADDWSEHISSSGK[136.11].K "sp|Q9BTA9|WAC_HUMAN,tr|A0A494C0B7|A0A494C0B7_HUMAN,tr|A0A0A0MRT2|A0A0A0MRT2_HUMAN,tr|A0A494C0C1|A0A494C0C1_HUMAN,tr|A0A494C0S5|A0A494C0S5_HUMAN,tr|A0A0A0MSR1|A0A0A0MSR1_HUMAN,tr|J3QTA0|J3QTA0_HUMAN,tr|C9JVK6|C9JVK6_HUMAN" 8 2261.944 2.59 133321 15212 3 2261.939924 754.9886 WW domain-containing adapter protein with coiled-coil OS=Homo sapiens OX=9606 GN=WAC PE=1 SV=3 4.03 2819.9 - 94434.4 - - - -1.8086 - 1.942 0.645 - 61.4 1 2 0 -0.0041 21 0 0 0 3.67E+06 1.42E+06 - - - 7.3212 1 221125_WJC_METTL3_EV_vs_WT_F09.15218.15218.4 1.89E-09 18/138 K.KPQDLAHTGISSGLIAGSSIQNPK.V sp|Q6ZU65|UBN2_HUMAN 1 2418.2867 1.38 133325 15218 4 2418.298432 605.5789 Ubinuclein-2 OS=Homo sapiens OX=9606 GN=UBN2 PE=1 SV=2 8.6 2820.8 - 372085 - - - 4.8567 - 3.38 0.646 - 231.5 1 2 0 0.0117 24 0 0 0 1.22E+07 8.80E+06 - - - 5.2364 0.999 221125_WJC_METTL3_EV_vs_WT_F09.15223.15223.3 1.09E-09 17/76 H.TPSQELALTQSVGGDSSADR[166.11].L "sp|Q86U44|MTA70_HUMAN,tr|H0YFV6|H0YFV6_HUMAN" 2 2027.9635 0 133328 15223 3 2027.964569 676.9951 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 4.03 2821.4 - 416582 - - - 0.5212 - 3.194 0.624 - 235.5 1 1 0 0.0011 20 0 0 0 1.16E+04 1.50E+07 - - - 8.314 1 221125_WJC_METTL3_EV_vs_WT_F09.15225.15225.3 2.13E-11 27/84 K.DHTPSQELALTQSVGGDSSADR[166.11].L "sp|Q86U44|MTA70_HUMAN,tr|H0YFV6|H0YFV6_HUMAN" 2 2280.0494 0.02 133330 15225 3 2281.042856 761.0237 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 4.22 2821.7 - 1.81E+06 - - - 435.7314 - 4.297 0.611 - 769.8 1 2 0 0.9935 22 0 0 0 5.19E+06 2.77E+08 - - - 8.5333 1 221125_WJC_METTL3_EV_vs_WT_F09.15231.15231.2 1.54E-09 14/38 H.TPSQELALTQSVGGDSSADR[166.11].L "sp|Q86U44|MTA70_HUMAN,tr|H0YFV6|H0YFV6_HUMAN" 2 2027.9635 0.001 133334 15231 2 2027.964201 1014.989 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 4.03 2822.5 - 109947 - - - 0.3397 - 3.221 0.658 - 444.5 1 1 0 0.0007 20 0 0 0 0.00E+00 3.51E+06 - - - 6.7765 1 221125_WJC_METTL3_EV_vs_WT_F09.15234.15234.3 0.000406 Jun-92 K.TQVEASEESALNHLQNPGDAAEGR.A "sp|Q9Y605|MOFA1_HUMAN,tr|A0A087WTY9|A0A087WTY9_HUMAN" 2 2522.1633 4.09 133335 15234 3 2522.165981 841.7284 MORF4 family-associated protein 1 OS=Homo sapiens OX=9606 GN=MRFAP1 PE=1 SV=1 4.25 2822.9 - 116175 - - - 1.0483 - 2.215 0.513 - 21.6 1 2 0 0.0026 24 0 0 0 1.26E+07 3.08E+06 - - - 6.1058 0.9996 221125_WJC_METTL3_EV_vs_WT_F09.15235.15235.4 0.000611 10/114 K.R[166.11]GLLQDDAHPTLVTYADHSK[136.11].L "sp|Q86U44|MTA70_HUMAN,tr|F5H6D8|F5H6D8_HUMAN,tr|H0YFV6|H0YFV6_HUMAN,tr|B4DTN4|B4DTN4_HUMAN" 4 2254.1461 0.01 133336 15235 4 2254.150249 564.5438 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 5.99 2823.1 - 103929 - - - 1.834 - 2.017 0.359 - 54.8 1 2 0 0.0041 20 0 0 0 2.10E+05 1.40E+07 - - - 2.5842 0.9352 221125_WJC_METTL3_EV_vs_WT_F09.15240.15240.4 2.61E-05 8/132 R.PLEGTSFIVDQANRPHC[160.03]VPDYHK.Q "sp|Q15942|ZYX_HUMAN,tr|H0Y2Y8|H0Y2Y8_HUMAN" 2 2679.2864 2.93 133339 15240 4 2679.297917 670.8289 Zyxin OS=Homo sapiens OX=9606 GN=ZYX PE=1 SV=1 6.02 2823.7 - 124954 - - - 4.3097 - 1.662 0.462 - 34.4 1 1 0 0.0115 23 0 0 0 9.73E+05 3.32E+05 - - - 3.4086 0.9999 221125_WJC_METTL3_EV_vs_WT_F09.15243.15243.3 5.08E-06 5/104 K.SRPNASGGAAC[160.03]SGPGPEPAVFC[160.03]EPVVK.L "sp|Q6L8Q7|PDE12_HUMAN,tr|F6T1Q0|F6T1Q0_HUMAN" 2 2697.2639 1.35 133342 15243 3 2697.26611 900.0952 "2',5'-phosphodiesterase 12 OS=Homo sapiens OX=9606 GN=PDE12 PE=1 SV=2" 5.86 2824.1 - 56821 - - - 0.8119 - 1.582 0.567 - 14.6 1 2 0 0.0022 27 0 0 0 8.99E+06 6.66E+06 - - - 5.9162 0.9907 221125_WJC_METTL3_EV_vs_WT_F09.15247.15247.4 0.0233 8/138 K.NIDDGTSDRPYSHALVAGIDRYPR.K "sp|P61353|RL27_HUMAN,tr|K7ELC7|K7ELC7_HUMAN" 2 2687.3052 0.97 133344 15247 4 2687.309852 672.8336 60S ribosomal protein L27 OS=Homo sapiens OX=9606 GN=RPL27 PE=1 SV=2 5.36 2824.7 - 153481 - - - 1.7345 - 1.354 0.287 - 27.3 1 2 1 0.0047 24 0 0 0 5.87E+06 6.08E+06 - - - 1.82 1 221125_WJC_METTL3_EV_vs_WT_F09.15254.15254.3 1.64E-11 13/104 K.SR[166.11]PNASGGAAC[160.03]SGPGPEPAVFC[160.03]EPVVK[136.11].L "sp|Q6L8Q7|PDE12_HUMAN,tr|F6T1Q0|F6T1Q0_HUMAN" 2 2715.2864 1.35 133349 15254 3 2715.285359 906.1027 "2',5'-phosphodiesterase 12 OS=Homo sapiens OX=9606 GN=PDE12 PE=1 SV=2" 5.86 2825.7 - 179777 - - - -0.3797 - 3.309 0.673 - 94.4 1 2 0 -0.001 27 0 0 0 8.99E+06 6.66E+06 - - - 8.796 0.9995 221125_WJC_METTL3_EV_vs_WT_F09.15262.15262.3 0.00026 Aug-68 R.K[136.11]DELSDWSLAGEDDR[166.11]DSR[166.11].H "sp|P51114|FXR1_HUMAN,tr|E7EU85|E7EU85_HUMAN,tr|E9PFF5|E9PFF5_HUMAN,tr|H7C4S4|H7C4S4_HUMAN,tr|B4DXZ6|B4DXZ6_HUMAN" 5 2120.9605 2.42 133355 15262 3 2120.960814 707.9941 Fragile X mental retardation syndrome-related protein 1 OS=Homo sapiens OX=9606 GN=FXR1 PE=1 SV=3 4.09 2826.8 - 54014.2 - - - 0.1504 - 1.656 0.472 - 55.7 1 2 1 0.0003 18 0 0 0 1.36E+06 5.62E+05 - - - 5.0583 0.9999 221125_WJC_METTL3_EV_vs_WT_F09.15263.15263.3 1.66E-05 Dec-52 K.KQELEEIC[160.03]HDLEAR.V sp|P35579|MYH9_HUMAN 1 1768.8414 0.94 133356 15263 3 1768.847494 590.6211 Myosin-9 OS=Homo sapiens OX=9606 GN=MYH9 PE=1 SV=4 4.57 2826.9 - 134308 - - - 3.4463 - 2.553 0.508 - 247.3 1 2 0 0.0061 14 0 0 0 3.93E+06 4.17E+06 - - - 6.6928 0.9952 221125_WJC_METTL3_EV_vs_WT_F09.15265.15265.3 0.0152 May-56 R.STSHK[136.11]PDEIYGMIER[166.11].L sp|Q86U44|MTA70_HUMAN 1 1779.8581 0.06 133358 15265 3 1779.858042 594.2933 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 5.42 2827.2 - 100364 - - - -0.0067 - 1.118 0.307 - 28.2 1 2 0 0 15 0 0 0 1.76E+05 2.86E+06 - - - 2.2538 0.9999 221125_WJC_METTL3_EV_vs_WT_F09.15267.15267.4 3.55E-06 9/108 R.VIHLSNLPHSGYSDSAVLK[136.11].L "sp|P43243|MATR3_HUMAN,tr|B3KM87|B3KM87_HUMAN,tr|A8MXP9|A8MXP9_HUMAN,tr|D6RBK5|D6RBK5_HUMAN,tr|A0A0R4J2E8|A0A0R4J2E8_HUMAN,tr|H0Y8T4|H0Y8T4_HUMAN,tr|D6REM6|D6REM6_HUMAN" 7 2044.0833 1.38 133359 15267 4 2044.087322 512.0281 Matrin-3 OS=Homo sapiens OX=9606 GN=MATR3 PE=1 SV=2 6.89 2827.4 - 136508 - - - 1.9725 - 2.313 0.46 - 74.7 1 2 0 0.004 19 0 0 0 4.24E+07 3.06E+07 - - - 3.5124 0.9998 221125_WJC_METTL3_EV_vs_WT_F09.15269.15269.4 6.68E-07 Dec-96 K.K[136.11]YFLHDDR[166.11]DDGVDYWAK[136.11].R "sp|Q9NYF8|BCLF1_HUMAN,tr|H0YF14|H0YF14_HUMAN" 2 2168.0173 1.88 133360 15269 4 2168.021968 543.0116 Bcl-2-associated transcription factor 1 OS=Homo sapiens OX=9606 GN=BCLAF1 PE=1 SV=2 4.66 2827.7 - 285771 - - - 2.1351 - 2.294 0.505 - 70.6 1 2 1 0.0046 17 0 0 0 1.77E+07 9.44E+06 - - - 3.9085 0.9981 221125_WJC_METTL3_EV_vs_WT_F09.15270.15270.4 0.0402 6/168 K.EGEEQPVLPEETESSK[136.11]PGPSAHDLAAQLK[136.11].S "sp|O95071|UBR5_HUMAN,tr|E7EMW7|E7EMW7_HUMAN" 2 3088.5172 0.58 133361 15270 4 3088.518726 773.1366 E3 ubiquitin-protein ligase UBR5 OS=Homo sapiens OX=9606 GN=UBR5 PE=1 SV=2 4.3 2827.8 - 124872 - - - 0.509 - 1.4 0.308 - 5.8 2 2 0 0.0016 29 0 0 0 1.30E+06 2.26E+06 - - - 1.7807 0.9804 221125_WJC_METTL3_EV_vs_WT_F09.15273.15273.4 0.0365 Jun-96 R.AHHVYPSLPTPLLRPSR.R sp|Q96HA1|P121A_HUMAN 1 1940.0745 1.65 133364 15273 4 1940.082698 486.0259 Nuclear envelope pore membrane protein POM 121 OS=Homo sapiens OX=9606 GN=POM121 PE=1 SV=2 10.84 2828.2 - 45374.1 - - - 4.2514 - 1.237 0.273 - 29 1 2 0 0.0082 17 0 0 0 1.75E+06 1.06E+06 - - - 1.6738 0.9941 221125_WJC_METTL3_EV_vs_WT_F09.15276.15276.4 0.0245 6/132 R.NLNVPATFPNSFPSHTEHSTAAK.L "sp|O43303|CP110_HUMAN,tr|I3L262|I3L262_HUMAN" 2 2466.1928 1.98 133365 15276 4 2466.199558 617.5555 Centriolar coiled-coil protein of 110 kDa OS=Homo sapiens OX=9606 GN=CCP110 PE=1 SV=3 6.92 2828.6 - 193691 - - - 2.7455 - 1.513 0.271 - 20.7 1 2 0 0.0068 23 0 0 0 7.05E+06 3.57E+06 - - - 1.7171 0.8458 221125_WJC_METTL3_EV_vs_WT_F09.15278.15278.4 0.0569 6/120 R.R[166.11]DGVNK[136.11]DYEETELISTTANYR[166.11].A "sp|Q13123|RED_HUMAN,tr|D6RAY9|D6RAY9_HUMAN,tr|D6REL4|D6REL4_HUMAN,tr|E7EQZ7|E7EQZ7_HUMAN" 4 2501.2029 0.95 133367 15278 4 2501.207952 626.308 Protein Red OS=Homo sapiens OX=9606 GN=IK PE=1 SV=3 4.51 2828.9 - 127547 - - - 2.0394 - 1.307 0.173 - 18.5 1 2 1 0.0051 21 0 0 0 1.58E+06 1.67E+06 - - - 0.8189 0.9999 221125_WJC_METTL3_EV_vs_WT_F09.15280.15280.4 8.57E-05 Oct-78 K.K[136.11]QELEEIC[160.03]HDLEAR[166.11].V sp|P35579|MYH9_HUMAN 1 1786.8639 1.1 133369 15280 4 1786.866611 447.7232 Myosin-9 OS=Homo sapiens OX=9606 GN=MYH9 PE=1 SV=4 4.57 2829.2 - 113538 - - - 1.5351 - 1.693 0.485 - 64.5 1 2 0 0.0027 14 0 0 0 1.59E+06 1.44E+06 - - - 3.6383 0.9885 221125_WJC_METTL3_EV_vs_WT_F09.15284.15284.4 3.46E-05 16/96 K.KYFLHDDRDDGVDYWAK.R "sp|Q9NYF8|BCLF1_HUMAN,tr|H0YF14|H0YF14_HUMAN" 2 2141.9807 1.86 133371 15284 4 2141.989698 536.5024 Bcl-2-associated transcription factor 1 OS=Homo sapiens OX=9606 GN=BCLAF1 PE=1 SV=2 4.66 2829.6 - 554096 - - - 4.2153 - 2.541 0.337 - 94.7 1 2 1 0.009 17 0 0 0 1.77E+07 9.48E+06 - - - 2.4805 0.9237 221125_WJC_METTL3_EV_vs_WT_F09.15286.15286.3 0.000218 Oct-88 L.SSSKGSLGGGFSSGGFSGGSFSR.G "sp|P13645|K1C10_HUMAN,tr|A0A1B0GVI3|A0A1B0GVI3_HUMAN" 2 2095.9559 999 133373 15286 3 2095.964574 699.6592 "Keratin, type I cytoskeletal 10 OS=Homo sapiens OX=9606 GN=KRT10 PE=1 SV=6" 11 2829.9 - 143087 - - - 4.1337 - 2.479 0.578 - 102.8 1 1 1 0.0087 23 0 0 0 1.65E+06 0.00E+00 - - - 7.1115 0.9997 221125_WJC_METTL3_EV_vs_WT_F09.15289.15289.4 0.000788 Sep-90 K.KHLEINPDHSIIETLR.Q sp|P07900|HS90A_HUMAN 1 1914.0323 0.61 133376 15289 4 1914.036542 479.5154 Heat shock protein HSP 90-alpha OS=Homo sapiens OX=9606 GN=HSP90AA1 PE=1 SV=5 6.01 2830.3 - 68233.1 - - - 2.211 - 2.134 0.396 - 88.6 1 2 0 0.0042 16 0 0 0 3.47E+06 5.65E+06 - - - 2.9386 0.9987 221125_WJC_METTL3_EV_vs_WT_F09.15294.15294.3 2.01E-07 15/92 K.TQVEASEESALNHLQNPGDAAEGR[166.11].A "sp|Q9Y605|MOFA1_HUMAN,tr|A0A087WTY9|A0A087WTY9_HUMAN" 2 2532.1716 4.08 133378 15294 3 2533.179012 845.0645 MORF4 family-associated protein 1 OS=Homo sapiens OX=9606 GN=MRFAP1 PE=1 SV=1 4.25 2831 - 139350 - - - 397.8423 - 2.884 0.522 - 143.4 1 2 0 1.0074 24 0 0 0 1.26E+07 3.08E+06 - - - 6.5408 0.9949 221125_WJC_METTL3_EV_vs_WT_F09.15302.15302.4 0.0774 8/132 R.NLNVPATFPNSFPSHTEHSTAAK[136.11].L "sp|O43303|CP110_HUMAN,tr|I3L262|I3L262_HUMAN" 2 2474.207 1.97 133384 15302 4 2474.209619 619.559 Centriolar coiled-coil protein of 110 kDa OS=Homo sapiens OX=9606 GN=CCP110 PE=1 SV=3 6.92 2832.1 - 126347 - - - 1.0638 - 1.672 0.232 - 32.8 1 2 0 0.0026 23 0 0 0 7.03E+06 3.57E+06 - - - 1.4111 0.9891 221125_WJC_METTL3_EV_vs_WT_F09.15304.15304.3 0.081 4/108 R.ATAPVPTVGEGYGYGHESELSQASAAAR[166.11].N "sp|Q9BWF3|RBM4_HUMAN,tr|E9PB51|E9PB51_HUMAN" 2 2785.3183 1.88 133386 15304 3 2785.32793 929.4467 RNA-binding protein 4 OS=Homo sapiens OX=9606 GN=RBM4 PE=1 SV=1 4.75 2832.4 - 52698.4 - - - 3.4678 - 0.907 0.404 - 7.8 1 2 0 0.0097 28 0 0 0 3.05E+06 1.62E+06 - - - 2.8169 0.9557 221125_WJC_METTL3_EV_vs_WT_F09.15316.15316.4 0.515 5/108 R.SQLESHSDQNMHQAEEWFK.C "sp|P07197|NFM_HUMAN,tr|E7ESP9|E7ESP9_HUMAN,tr|E7EMV2|E7EMV2_HUMAN" 3 2330.0022 3.86 133394 15316 4 2330.018297 583.5078 Neurofilament medium polypeptide OS=Homo sapiens OX=9606 GN=NEFM PE=1 SV=3 4.8 2834.1 - 111133 - - - 6.9047 - 1.171 0.318 - 18.4 1 2 0 0.0161 19 0 0 0 1.85E+06 4.80E+05 - - - 2.0428 0.9994 221125_WJC_METTL3_EV_vs_WT_F09.15317.15317.4 0.000964 7/162 K.GQGPGGDGFYLPTAGAPGSLHSHAPSAR.T "sp|O15417|TNC18_HUMAN,tr|H9KVB4|H9KVB4_HUMAN" 2 2661.2684 3.17 133395 15317 4 2661.280322 666.3244 Trinucleotide repeat-containing gene 18 protein OS=Homo sapiens OX=9606 GN=TNRC18 PE=1 SV=3 6.92 2834.2 - 91275.7 - - - 4.4757 - 1.848 0.469 - 21.5 1 2 0 0.0119 28 0 0 0 9.13E+06 2.88E+06 - - - 3.4955 0.9976 221125_WJC_METTL3_EV_vs_WT_F09.15338.15338.3 0.0301 May-72 R.KQTIDNSQGAYQEAFDISK.K sp|P27348|1433T_HUMAN 1 2142.0229 0.15 133410 15338 3 2142.02633 715.0149 14-3-3 protein theta OS=Homo sapiens OX=9606 GN=YWHAQ PE=1 SV=1 4.56 2837.1 - 44642.9 - - - 1.5887 - 1.306 0.341 - 15.3 1 2 0 0.0034 19 0 0 0 6.26E+05 4.26E+06 - - - 2.9968 0.9999 221125_WJC_METTL3_EV_vs_WT_F09.15340.15340.3 0.000295 Sep-52 K.K[136.11]GPGEVAGTVTGQK[136.11].R "sp|Q86U44|MTA70_HUMAN,tr|F5H6D8|F5H6D8_HUMAN,tr|H0YFV6|H0YFV6_HUMAN,tr|B4DTN4|B4DTN4_HUMAN" 4 1343.738 0 133411 15340 3 1343.740475 448.9199 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 8.59 2837.4 - 90814 - - - 1.8575 - 1.969 0.544 - 124.2 1 2 0 0.0025 14 0 0 0 1.99E+04 4.37E+06 - - - 6.4049 1 221125_WJC_METTL3_EV_vs_WT_F09.15344.15344.3 3.28E-10 11/104 K.QGAESDQAEPIIC[160.03]SSGAEAPANSLPSK.V sp|Q7Z434|MAVS_HUMAN 1 2713.2501 0.87 133414 15344 3 2713.258542 905.424 Mitochondrial antiviral-signaling protein OS=Homo sapiens OX=9606 GN=MAVS PE=1 SV=2 4 2837.9 - 100211 - - - 3.1099 - 2.781 0.666 - 64.1 1 2 0 0.0084 27 0 0 0 1.95E+06 2.24E+06 - - - 8.316 0.9992 221125_WJC_METTL3_EV_vs_WT_F09.15345.15345.3 0.000625 6/104 K.QGAESDQAEPIIC[160.03]SSGAEAPANSLPSK[136.11].V sp|Q7Z434|MAVS_HUMAN 1 2721.2643 0.87 133415 15345 3 2721.271285 908.0954 Mitochondrial antiviral-signaling protein OS=Homo sapiens OX=9606 GN=MAVS PE=1 SV=2 4 2838 - 90252.8 - - - 2.5654 - 1.503 0.433 - 22.3 1 2 0 0.007 27 0 0 0 1.95E+06 2.24E+06 - - - 4.303 0.9999 221125_WJC_METTL3_EV_vs_WT_F09.15357.15357.4 9.82E-05 14/162 K.GQGPGGDGFYLPTAGAPGSLHSHAPSAR[166.11].T "sp|O15417|TNC18_HUMAN,tr|H9KVB4|H9KVB4_HUMAN" 2 2671.2767 3.11 133423 15357 4 2671.281908 668.8264 Trinucleotide repeat-containing gene 18 protein OS=Homo sapiens OX=9606 GN=TNRC18 PE=1 SV=3 6.92 2839.7 - 143916 - - - 1.9567 - 2.439 0.454 - 85.7 1 2 0 0.0052 28 0 0 0 8.95E+06 2.88E+06 - - - 3.453 0.9882 221125_WJC_METTL3_EV_vs_WT_F09.15369.15369.4 6.35E-08 12/144 V.AAFASSLVSGLNSSASEPAK[136.11]EPAK[136.11]K[136.11].S "sp|Q86U44|MTA70_HUMAN,tr|F5H6D8|F5H6D8_HUMAN,tr|H0YFV6|H0YFV6_HUMAN,tr|B4DTN4|B4DTN4_HUMAN" 4 2470.313 0.001 133430 15369 4 2470.316829 618.5855 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 8.54 2841.4 - 208005 - - - 1.563 - 2.973 0.554 - 66.4 1 1 1 0.0039 25 0 0 0 0.00E+00 3.01E+07 - - - 4.3936 0.9878 221125_WJC_METTL3_EV_vs_WT_F09.15390.15390.3 0.018 4/108 K.QEVPVPGDGVEFPSSTGAEGQTGHPAEK.L "sp|Q92618|ZN516_HUMAN,tr|A0A087WUJ4|A0A087WUJ4_HUMAN" 2 2806.3046 1.25 133442 15390 3 2806.314355 936.4421 Zinc finger protein 516 OS=Homo sapiens OX=9606 GN=ZNF516 PE=1 SV=1 4.25 2844.3 - 46919.5 - - - 3.4825 - 1.095 0.359 - 9.7 1 2 0 0.0098 28 0 0 0 1.11E+06 8.87E+05 - - - 2.7486 0.9587 221125_WJC_METTL3_EV_vs_WT_F09.15396.15396.3 0.00838 6/104 P.TAPTSGGPK[136.11]PSTASAVPELATDPELEK[136.11].K "sp|Q86U44|MTA70_HUMAN,tr|B4E349|B4E349_HUMAN,tr|F5H6D8|F5H6D8_HUMAN,tr|H0YFV6|H0YFV6_HUMAN,tr|B4DTN4|B4DTN4_HUMAN" 5 2666.3622 0.001 133445 15396 3 2666.360931 889.7947 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 4.41 2845.1 - 44995.9 - - - -0.4598 - 1.523 0.401 - 21.3 1 1 0 -0.0012 27 0 0 0 0.00E+00 2.35E+06 - - - 3.9782 0.8535 221125_WJC_METTL3_EV_vs_WT_F09.15416.15416.3 1.58 May-72 R.GLLQDDAHPTLVTYADHSK[136.11].L "sp|Q86U44|MTA70_HUMAN,tr|F5H6D8|F5H6D8_HUMAN,tr|H0YFV6|H0YFV6_HUMAN,tr|B4DTN4|B4DTN4_HUMAN" 4 2088.0367 0.01 133454 15416 3 2088.040492 697.0195 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 5.13 2848 - 74286.4 - - - 1.8003 - 1.149 0.158 - 25.2 2 2 0 0.0038 19 0 0 0 7.20E+04 1.11E+07 - - - 0.5024 1 221125_WJC_METTL3_EV_vs_WT_F09.15421.15421.4 0.00455 10/108 R.GLLQDDAHPTLVTYADHSK[136.11].L "sp|Q86U44|MTA70_HUMAN,tr|F5H6D8|F5H6D8_HUMAN,tr|H0YFV6|H0YFV6_HUMAN,tr|B4DTN4|B4DTN4_HUMAN" 4 2088.0367 0.02 133457 15421 4 2088.037874 523.0165 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 5.13 2848.6 - 205445 - - - 0.5464 - 2.13 0.493 - 92.8 1 2 0 0.0011 19 0 0 0 5.95E+05 2.75E+07 - - - 3.7725 0.9973 221125_WJC_METTL3_EV_vs_WT_F09.15424.15424.4 0.0007 8/120 K.TTQFSC[160.03]TLGEKFEETTADGRK.T "sp|Q01469|FABP5_HUMAN,tr|I6L8B7|I6L8B7_HUMAN" 2 2405.1169 60.4 133458 15424 4 2405.123026 602.2865 Fatty acid-binding protein 5 OS=Homo sapiens OX=9606 GN=FABP5 PE=1 SV=3 4.87 2849 - 105648 - - - 2.545 - 1.661 0.369 - 48.8 1 2 1 0.0061 21 0 0 0 6.39E+06 1.06E+05 - - - 2.6039 1 221125_WJC_METTL3_EV_vs_WT_F09.15425.15425.4 1.06E-06 11/198 R.SDSPVPTAPTSGGPK[136.11]PSTASAVPELATDPELEK[136.11]K[136.11].L "sp|Q86U44|MTA70_HUMAN,tr|B4E349|B4E349_HUMAN,tr|F5H6D8|F5H6D8_HUMAN,tr|B4DTN4|B4DTN4_HUMAN" 4 3384.7363 0 133459 15425 4 3384.740937 847.1913 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 4.51 2849.2 - 101569 - - - 1.3815 - 2.399 0.537 - 45.4 1 2 0 0.0047 34 0 0 0 2.64E+05 4.05E+08 - - - 4.1597 0.8884 221125_WJC_METTL3_EV_vs_WT_F09.15439.15439.3 0.771 7/104 L.STSSEPAAKPEVDPVENEAVAPEFTNR.N sp|Q9H0U6|RM18_HUMAN 1 2870.357 1.66 133467 15439 3 2870.357373 957.7929 "39S ribosomal protein L18, mitochondrial OS=Homo sapiens OX=9606 GN=MRPL18 PE=1 SV=1" 4.14 2851.2 - 59864 - - - 0.1261 - 1.786 0.297 - 40.3 1 1 0 0.0004 27 0 0 0 1.58E+07 9.55E+06 - - - 3.1855 0.9965 221125_WJC_METTL3_EV_vs_WT_F09.15440.15440.3 0.00199 Jun-52 K.SGK[136.11]WEGLVYAPPGK[136.11].E "sp|Q9Y2W1|TR150_HUMAN,tr|A0A3B3ITZ9|A0A3B3ITZ9_HUMAN" 2 1503.8057 2.66 133468 15440 3 1503.808311 502.2758 Thyroid hormone receptor-associated protein 3 OS=Homo sapiens OX=9606 GN=THRAP3 PE=1 SV=2 8.22 2851.3 - 74076.3 - - - 1.7595 - 1.446 0.393 - 45.6 1 2 1 0.0026 14 0 0 0 8.49E+06 3.19E+06 - - - 3.9009 0.9244 221125_WJC_METTL3_EV_vs_WT_F09.15441.15441.3 0.00258 5/104 L.STSSEPAAK[136.11]PEVDPVENEAVAPEFTNR[166.11].N sp|Q9H0U6|RM18_HUMAN 1 2888.3795 1.66 133469 15441 3 2888.37799 963.8004 "39S ribosomal protein L18, mitochondrial OS=Homo sapiens OX=9606 GN=MRPL18 PE=1 SV=1" 4.14 2851.5 - 66076.7 - - - -0.5162 - 1.61 0.346 - 16.6 1 1 0 -0.0015 27 0 0 0 1.58E+07 9.55E+06 - - - 3.4928 0.9994 221125_WJC_METTL3_EV_vs_WT_F09.15450.15450.3 0.00448 Jun-88 K.ESVTDYTTPSSSLPNTVATNNTK.M "sp|Q9Y520|PRC2C_HUMAN,tr|E7EPN9|E7EPN9_HUMAN,tr|A0A2R8Y7F4|A0A2R8Y7F4_HUMAN,tr|A0A2R8YET2|A0A2R8YET2_HUMAN" 4 2426.1449 2.81 133472 15450 3 2426.150522 809.7222 Protein PRRC2C OS=Homo sapiens OX=9606 GN=PRRC2C PE=1 SV=4 4.37 2852.8 - 92680.3 - - - 2.3201 - 1.556 0.425 - 31.6 1 2 0 0.0056 23 0 0 0 4.79E+06 1.70E+06 - - - 4.314 0.9944 221125_WJC_METTL3_EV_vs_WT_F09.15451.15451.4 0.232 9/114 R.DAK[136.11]LDK[136.11]AQIHDLVLVGGSTR[166.11].L "sp|P0DMV8|HS71A_HUMAN,sp|P0DMV9|HS71B_HUMAN,tr|V9GZ37|V9GZ37_HUMAN,tr|A0A0G2JIW1|A0A0G2JIW1_HUMAN" 4 2161.2065 0.1 133473 15451 4 2161.211557 541.3089 Heat shock 70 kDa protein 1A OS=Homo sapiens OX=9606 GN=HSPA1A PE=1 SV=1 6.75 2852.9 - 80991.9 - - - 2.3232 - 1.973 0.315 - 46.7 1 2 2 0.005 20 0 0 0 2.97E+05 2.84E+06 - - - 2.1936 0.9998 221125_WJC_METTL3_EV_vs_WT_F09.15455.15455.4 8.35E-05 10/114 K.R[166.11]GLLQDDAHPTLVTYADHSK[136.11].L "sp|Q86U44|MTA70_HUMAN,tr|F5H6D8|F5H6D8_HUMAN,tr|H0YFV6|H0YFV6_HUMAN,tr|B4DTN4|B4DTN4_HUMAN" 4 2254.1461 0.04 133475 15455 4 2254.151911 564.5438 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 5.99 2853.5 - 59655.1 - - - 2.5713 - 2.127 0.433 - 75.7 1 2 0 0.0058 20 0 0 0 2.72E+05 7.74E+06 - - - 3.2455 0.8427 221125_WJC_METTL3_EV_vs_WT_F09.15457.15457.3 1.01 Apr-88 R.QQHQSQAVTVPPPGLESFPSQAK.L sp|Q5T6F2|UBAP2_HUMAN 1 2460.2397 3.81 133477 15457 3 2460.240405 821.0872 Ubiquitin-associated protein 2 OS=Homo sapiens OX=9606 GN=UBAP2 PE=1 SV=1 6.75 2853.8 - 35969.2 - - - 0.2715 - 0.909 0.166 - 11.7 1 2 0 0.0007 23 0 0 0 1.22E+06 3.19E+05 - - - 0.1667 1 221125_WJC_METTL3_EV_vs_WT_F09.15460.15460.3 8.11E-09 22/84 K.DHTPSQELALTQSVGGDSSADR[166.11].L "sp|Q86U44|MTA70_HUMAN,tr|H0YFV6|H0YFV6_HUMAN" 2 2280.0494 0.01 133478 15460 3 2280.049272 761.0237 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 4.22 2854.2 - 371235 - - - -0.0417 - 4.054 0.679 - 557.5 1 2 0 -0.0001 22 0 0 0 2.11E+05 1.87E+07 - - - 9.4286 0.991 221125_WJC_METTL3_EV_vs_WT_F09.15461.15461.3 0.125 May-88 K.ESVTDYTTPSSSLPNTVATNNTK[136.11].M "sp|Q9Y520|PRC2C_HUMAN,tr|E7EPN9|E7EPN9_HUMAN,tr|A0A2R8Y7F4|A0A2R8Y7F4_HUMAN,tr|A0A2R8YET2|A0A2R8YET2_HUMAN" 4 2434.1591 2.81 133479 15461 3 2434.157303 812.3936 Protein PRRC2C OS=Homo sapiens OX=9606 GN=PRRC2C PE=1 SV=4 4.37 2854.4 - 33201.4 - - - -0.7354 - 1.098 0.279 - 21.2 1 2 0 -0.0018 23 0 0 0 4.79E+06 1.70E+06 - - - 1.8694 0.9686 221125_WJC_METTL3_EV_vs_WT_F09.15491.15491.3 0.0409 Jul-56 R.STSHK[136.11]PDEIYGMIER[166.11].L sp|Q86U44|MTA70_HUMAN 1 1779.8581 0.02 133494 15491 3 1779.867552 594.2933 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 5.42 2858.6 - 66010.7 - - - 5.3364 - 1.462 0.312 - 66.4 1 2 0 0.0095 15 0 0 0 5.47E+04 2.57E+06 - - - 3.0069 0.9991 221125_WJC_METTL3_EV_vs_WT_F09.15496.15496.4 0.00743 5/126 R.KTQTVC[160.03]NFTDGALVQHQEWDGK.E "sp|Q01469|FABP5_HUMAN,tr|I6L8B7|I6L8B7_HUMAN" 2 2561.1969 24.36 133496 15496 4 2561.198349 641.3065 Fatty acid-binding protein 5 OS=Homo sapiens OX=9606 GN=FABP5 PE=1 SV=3 5.38 2859.3 - 59239.2 - - - 0.5712 - 1.51 0.314 - 13.4 1 2 0 0.0015 22 0 0 0 3.09E+06 1.27E+05 - - - 2.0935 0.9999 221125_WJC_METTL3_EV_vs_WT_F09.15509.15509.4 2.44E-06 11/132 R.SLSTTNVFAC[160.03]SDRPTVIYSSNHK.L "sp|Q16531|DDB1_HUMAN,tr|A0A7P0TAK7|A0A7P0TAK7_HUMAN,tr|A0A7P0T870|A0A7P0T870_HUMAN,tr|A0A7P0TB30|A0A7P0TB30_HUMAN,tr|A0A7P0Z3Z5|A0A7P0Z3Z5_HUMAN,tr|F5GY55|F5GY55_HUMAN,tr|A0A7P0Z4B9|A0A7P0Z4B9_HUMAN,tr|A0A7P0T965|A0A7P0T965_HUMAN" 8 2583.2388 0.66 133502 15509 4 2583.240145 646.817 DNA damage-binding protein 1 OS=Homo sapiens OX=9606 GN=DDB1 PE=1 SV=1 7.95 2861.1 - 245931 - - - 0.5396 - 2.545 0.4 - 71.3 1 2 0 0.0014 23 0 0 0 5.35E+06 8.14E+06 - - - 3.0099 1 221125_WJC_METTL3_EV_vs_WT_F09.15510.15510.3 6.56E-10 14/132 R.SDSPVPTAPTSGGPK[136.11]PSTASAVPELATDPELEK[136.11]K[136.11].L "sp|Q86U44|MTA70_HUMAN,tr|B4E349|B4E349_HUMAN,tr|F5H6D8|F5H6D8_HUMAN,tr|B4DTN4|B4DTN4_HUMAN" 4 3384.7363 0.001 133503 15510 3 3384.736853 1129.2527 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 4.51 2861.3 - 163923 - - - 0.1749 - 2.699 0.622 - 86.5 1 2 0 0.0006 34 0 0 0 0.00E+00 1.15E+07 - - - 7.7588 0.9862 221125_WJC_METTL3_EV_vs_WT_F09.15516.15516.3 0.0962 Apr-80 K.YQGDGIVEDEEETMENNEEKK.D "sp|Q9NYF8|BCLF1_HUMAN,tr|H0YF63|H0YF63_HUMAN,tr|E9PK91|E9PK91_HUMAN,tr|H0YF14|H0YF14_HUMAN" 4 2485.0439 4.66 133506 15516 3 2485.046002 829.3552 Bcl-2-associated transcription factor 1 OS=Homo sapiens OX=9606 GN=BCLAF1 PE=1 SV=2 3.89 2862.1 - 93812.7 - - - 0.8624 - 0.995 0.279 - 9.9 1 2 0 0.0021 21 0 0 0 3.01E+06 6.45E+05 - - - 1.638 1 221125_WJC_METTL3_EV_vs_WT_F09.15522.15522.3 4.04E-06 12/120 R.GAPAAAAAAAPPPTPAPPPPPAPVAAAAPAR.A sp|Q6SPF0|SAMD1_HUMAN 1 2661.4391 8.56 133509 15522 3 2661.43389 888.1536 Sterile alpha motif domain-containing protein 1 OS=Homo sapiens OX=9606 GN=SAMD1 PE=1 SV=1 9.75 2862.9 - 118631 - - - -1.9598 - 2.973 0.538 - 91.4 1 2 0 -0.0052 31 0 0 0 8.74E+06 1.02E+06 - - - 7.0434 0.9996 221125_WJC_METTL3_EV_vs_WT_F09.15523.15523.3 2.73E-07 Oct-72 K.QGEDNSTAQDTEELEK[136.11]EIR[166.11].E "sp|Q86UE4|LYRIC_HUMAN,tr|E5RJU9|E5RJU9_HUMAN" 2 2209.0101 0.94 133510 15523 3 2209.000715 737.344 Protein LYRIC OS=Homo sapiens OX=9606 GN=MTDH PE=1 SV=2 4 2863 - 139390 - - - -4.2639 - 2.423 0.674 - 111.2 1 2 1 -0.0094 19 0 0 0 2.83E+06 3.02E+06 - - - 8.2261 0.9999 221125_WJC_METTL3_EV_vs_WT_F09.15527.15527.4 8.73E-07 16/132 R.SLSTTNVFAC[160.03]SDR[166.11]PTVIYSSNHK[136.11].L "sp|Q16531|DDB1_HUMAN,tr|A0A7P0TAK7|A0A7P0TAK7_HUMAN,tr|A0A7P0T870|A0A7P0T870_HUMAN,tr|A0A7P0TB30|A0A7P0TB30_HUMAN,tr|A0A7P0Z3Z5|A0A7P0Z3Z5_HUMAN,tr|F5GY55|F5GY55_HUMAN,tr|A0A7P0Z4B9|A0A7P0Z4B9_HUMAN,tr|A0A7P0T965|A0A7P0T965_HUMAN" 8 2601.2612 0.66 133512 15527 4 2601.256324 651.3226 DNA damage-binding protein 1 OS=Homo sapiens OX=9606 GN=DDB1 PE=1 SV=1 7.95 2863.5 - 485492 - - - -1.8825 - 3.081 0.467 - 157 1 2 0 -0.0049 23 0 0 0 5.35E+06 8.14E+06 - - - 3.654 0.9965 221125_WJC_METTL3_EV_vs_WT_F09.15531.15531.3 0.000124 Sep-40 K.FAAQELIEVK[136.11]R[166.11].G "sp|Q86U44|MTA70_HUMAN,tr|F5H6D8|F5H6D8_HUMAN,tr|H0YFV6|H0YFV6_HUMAN,tr|B4DTN4|B4DTN4_HUMAN" 4 1320.7521 0 133513 15531 3 1320.750385 441.258 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 6.14 2864.1 - 130952 - - - -1.2652 - 1.406 0.273 - 86.9 1 2 0 -0.0017 11 0 0 0 3.04E+04 2.29E+07 - - - 2.5512 0.9999 221125_WJC_METTL3_EV_vs_WT_F09.15557.15557.3 0.000445 Jun-52 K.K[136.11]GPGEVAGTVTGQK[136.11].R "sp|Q86U44|MTA70_HUMAN,tr|F5H6D8|F5H6D8_HUMAN,tr|H0YFV6|H0YFV6_HUMAN,tr|B4DTN4|B4DTN4_HUMAN" 4 1343.738 0.001 133523 15557 3 1343.737164 448.9199 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 8.59 2867.9 - 95725.2 - - - -0.6065 - 1.592 0.516 - 61.7 1 2 0 -0.0008 14 0 0 0 0.00E+00 8.69E+06 - - - 5.5284 0.9989 221125_WJC_METTL3_EV_vs_WT_F09.15563.15563.2 0.000179 20-Jun K.FAAQELIEVK[136.11]R[166.11].G "sp|Q86U44|MTA70_HUMAN,tr|F5H6D8|F5H6D8_HUMAN,tr|H0YFV6|H0YFV6_HUMAN,tr|B4DTN4|B4DTN4_HUMAN" 4 1320.7521 0.001 133527 15563 2 1320.753319 661.3833 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 6.14 2868.7 - 59234.7 - - - 0.9563 - 1.527 0.312 - 146.5 1 2 0 0.0013 11 0 0 0 0.00E+00 1.35E+06 - - - 2.4902 1 221125_WJC_METTL3_EV_vs_WT_F09.15567.15567.4 3.34E-05 15/180 R.GAPAAAAAAAPPPTPAPPPPPAPVAAAAPAR.A sp|Q6SPF0|SAMD1_HUMAN 1 2661.4391 4.71 133528 15567 4 2661.439054 666.3671 Sterile alpha motif domain-containing protein 1 OS=Homo sapiens OX=9606 GN=SAMD1 PE=1 SV=1 9.75 2869.4 - 71831.1 - - - -0.0195 - 3.331 0.563 - 114.2 1 2 0 -0.0001 31 0 0 0 2.03E+06 4.31E+05 - - - 4.492 0.9998 221125_WJC_METTL3_EV_vs_WT_F09.15573.15573.3 0.00195 5/100 K.QGTFC[160.03]VDC[160.03]ETYHTAASTLGSQGQTGK[136.11].L "sp|Q9H944|MED20_HUMAN,tr|A6PVP4|A6PVP4_HUMAN,tr|B7ZBQ3|B7ZBQ3_HUMAN" 3 2811.232 1.57 133531 15573 3 2811.236387 938.0846 Mediator of RNA polymerase II transcription subunit 20 OS=Homo sapiens OX=9606 GN=MED20 PE=1 SV=1 5.32 2870.2 - 59709.3 - - - 1.5755 - 1.479 0.476 - 20 1 2 0 0.0044 26 0 0 0 1.13E+06 7.18E+05 - - - 4.7461 1 221125_WJC_METTL3_EV_vs_WT_F09.15574.15574.3 4.97E-05 11/100 K.QGTFC[160.03]VDC[160.03]ETYHTAASTLGSQGQTGK.L "sp|Q9H944|MED20_HUMAN,tr|A6PVP4|A6PVP4_HUMAN,tr|B7ZBQ3|B7ZBQ3_HUMAN" 3 2803.2178 1.57 133532 15574 3 2803.222538 935.4132 Mediator of RNA polymerase II transcription subunit 20 OS=Homo sapiens OX=9606 GN=MED20 PE=1 SV=1 5.32 2870.3 - 86030.8 - - - 1.7052 - 2.416 0.637 - 95.3 1 2 0 0.0048 26 0 0 0 1.13E+06 7.18E+05 - - - 7.67 0.9996 221125_WJC_METTL3_EV_vs_WT_F09.15583.15583.4 0.000287 9/132 R.DRPQNVDISRPPEEALVTVPAHQ.- "sp|Q16877|F264_HUMAN,tr|Q66S35|Q66S35_HUMAN" 2 2567.3092 3.56 133537 15583 4 2567.314456 642.8346 "6-phosphofructo-2-kinase\fructose-2,6-bisphosphatase 4 OS=Homo sapiens OX=9606 GN=PFKFB4 PE=1 SV=6" 4.75 2871.6 - 122925 - - - 2.0418 - 1.963 0.373 - 45.5 1 2 0 0.0052 23 0 0 0 4.09E+06 1.15E+06 - - - 2.6897 0.9895 221125_WJC_METTL3_EV_vs_WT_F09.15599.15599.4 0.00585 9/126 R.GGC[160.03]NITAIQDVTGAHIDVDKQK.D "sp|Q8IWZ3|ANKH1_HUMAN,tr|A0A0A0MQZ8|A0A0A0MQZ8_HUMAN,tr|H0Y472|H0Y472_HUMAN,tr|H0Y7Y3|H0Y7Y3_HUMAN,tr|H0Y4P6|H0Y4P6_HUMAN,tr|H0Y785|H0Y785_HUMAN" 6 2339.154 1.42 133546 15599 4 2339.16184 585.7958 Ankyrin repeat and KH domain-containing protein 1 OS=Homo sapiens OX=9606 GN=ANKHD1 PE=1 SV=1 5.3 2873.9 - 125148 - - - 3.3692 - 1.712 0.326 - 46.3 1 2 1 0.0079 22 0 0 0 9.90E+06 6.97E+06 - - - 2.2372 0.9888 221125_WJC_METTL3_EV_vs_WT_F09.15601.15601.4 0.0267 7/132 R.DR[166.11]PQNVDISR[166.11]PPEEALVTVPAHQ.- "sp|Q16877|F264_HUMAN,tr|Q66S35|Q66S35_HUMAN" 2 2587.3258 3.72 133548 15601 4 2587.336933 647.8387 "6-phosphofructo-2-kinase\fructose-2,6-bisphosphatase 4 OS=Homo sapiens OX=9606 GN=PFKFB4 PE=1 SV=6" 4.75 2874.2 - 55024.3 - - - 4.3207 - 1.486 0.295 - 32.1 1 2 0 0.0112 23 0 0 0 3.91E+06 1.05E+06 - - - 1.9189 0.9977 221125_WJC_METTL3_EV_vs_WT_F09.15602.15602.3 0.0196 May-80 R.C[160.03]ESAPGC[160.03]GVWQRPVIDNPNYK.G "sp|P27824|CALX_HUMAN,tr|A0A7P0T937|A0A7P0T937_HUMAN,tr|A0A7P0T840|A0A7P0T840_HUMAN,tr|A0A7P0TB65|A0A7P0TB65_HUMAN,tr|A0A7P0TAE9|A0A7P0TAE9_HUMAN,tr|D6RGY2|D6RGY2_HUMAN,tr|A0A7P0T8G1|A0A7P0T8G1_HUMAN,tr|A0A7P0Z4D6|A0A7P0Z4D6_HUMAN,tr|A0A7P0Z484|A0A7P0Z484_HUMAN,tr|A0A7P0TAR9|A0A7P0TAR9_HUMAN,tr|A0A7P0T9L0|A0A7P0T9L0_HUMAN" 11 2446.1158 1.59 133549 15602 3 2446.117959 816.3792 Calnexin OS=Homo sapiens OX=9606 GN=CANX PE=1 SV=2 6.05 2874.3 - 50226 - - - 0.883 - 1.124 0.353 - 25.1 1 2 0 0.0022 21 0 0 0 9.04E+05 5.69E+05 - - - 2.7552 0.9944 221125_WJC_METTL3_EV_vs_WT_F09.15605.15605.3 0.0624 Jul-52 K.K[136.11]K[136.11]ELEEIVQPIISK[136.11].L "sp|P11021|BIP_HUMAN,tr|A0A7P0TB36|A0A7P0TB36_HUMAN,tr|A0A7P0TAI0|A0A7P0TAI0_HUMAN" 3 1677.0139 0.49 133550 15605 3 1677.016635 560.0119 Endoplasmic reticulum chaperone BiP OS=Homo sapiens OX=9606 GN=HSPA5 PE=1 SV=2 6.23 2874.8 - 60653.3 - - - 1.647 - 1.547 0.34 - 66.5 1 2 1 0.0028 14 0 0 0 3.13E+06 6.42E+06 - - - 3.4894 0.9999 221125_WJC_METTL3_EV_vs_WT_F09.15617.15617.4 1.22E-07 15/126 R.GGC[160.03]NITAIQDVTGAHIDVDK[136.11]QK[136.11].D "sp|Q8IWZ3|ANKH1_HUMAN,tr|A0A0A0MQZ8|A0A0A0MQZ8_HUMAN,tr|H0Y472|H0Y472_HUMAN,tr|H0Y7Y3|H0Y7Y3_HUMAN,tr|H0Y4P6|H0Y4P6_HUMAN,tr|H0Y785|H0Y785_HUMAN" 6 2355.1824 1.42 133556 15617 4 2355.184302 589.8029 Ankyrin repeat and KH domain-containing protein 1 OS=Homo sapiens OX=9606 GN=ANKHD1 PE=1 SV=1 5.3 2876.4 - 159682 - - - 0.825 - 3.095 0.587 - 187 1 2 1 0.0019 22 0 0 0 1.01E+07 7.09E+06 - - - 4.7044 0.9998 221125_WJC_METTL3_EV_vs_WT_F09.15619.15619.4 0.000713 9/138 R.IVSR[166.11]PEELR[166.11]EDDVGTGAGLLEIK[136.11]K[136.11].L "sp|P49368|TCPG_HUMAN,tr|B4DUR8|B4DUR8_HUMAN" 2 2659.463 0.17 133558 15619 4 2659.46754 665.873 T-complex protein 1 subunit gamma OS=Homo sapiens OX=9606 GN=CCT3 PE=1 SV=4 4.66 2876.6 - 86557.7 - - - 1.694 - 2.371 0.524 - 41.5 1 2 1 0.0045 24 0 0 0 9.46E+05 5.53E+06 - - - 4.0627 0.9974 221125_WJC_METTL3_EV_vs_WT_F09.15638.15638.3 2.72E-05 Aug-52 K.KKELEEIVQPIISK.L "sp|P11021|BIP_HUMAN,tr|A0A7P0TB36|A0A7P0TB36_HUMAN,tr|A0A7P0TAI0|A0A7P0TAI0_HUMAN" 3 1652.9713 0.48 133569 15638 3 1652.976976 551.9977 Endoplasmic reticulum chaperone BiP OS=Homo sapiens OX=9606 GN=HSPA5 PE=1 SV=2 6.23 2879.2 - 86935.5 - - - 3.4502 - 1.613 0.478 - 70.3 1 2 1 0.0057 14 0 0 0 3.13E+06 6.47E+06 - - - 5.1382 0.9977 221125_WJC_METTL3_EV_vs_WT_F09.15655.15655.3 0.0187 Apr-80 R.SNSVGIQDAFNDGSDSTFQKR.N "sp|O14497|ARI1A_HUMAN,tr|H0Y488|H0Y488_HUMAN,tr|A0A1B0GTU5|A0A1B0GTU5_HUMAN,tr|A0A087WUV6|A0A087WUV6_HUMAN" 4 2272.0356 1.45 133575 15655 3 2272.036303 758.3525 AT-rich interactive domain-containing protein 1A OS=Homo sapiens OX=9606 GN=ARID1A PE=1 SV=3 4.43 2881.9 - 53121.8 - - - 0.3019 - 0.949 0.387 - 10.1 1 2 0 0.0007 21 0 0 0 1.56E+06 1.07E+06 - - - 2.729 0.9995 221125_WJC_METTL3_EV_vs_WT_F09.15670.15670.4 0.00256 9/108 R.GLLQDDAHPTLVTYADHSK[136.11].L "sp|Q86U44|MTA70_HUMAN,tr|F5H6D8|F5H6D8_HUMAN,tr|H0YFV6|H0YFV6_HUMAN,tr|B4DTN4|B4DTN4_HUMAN" 4 2088.0367 0.02 133583 15670 4 2088.035897 523.0165 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 5.13 2884 - 142377 - - - -0.4004 - 1.962 0.339 - 66.4 1 2 0 -0.0008 19 0 0 0 1.52E+05 8.76E+06 - - - 2.4044 0.9989 221125_WJC_METTL3_EV_vs_WT_F09.15672.15672.4 0.033 6/108 R.DGSAFEDGLR[166.11]HPFIVNHPK[136.11].V "sp|P55265|DSRAD_HUMAN,tr|A0A3B3IRQ9|A0A3B3IRQ9_HUMAN,tr|A0A7P0Z4K3|A0A7P0Z4K3_HUMAN,tr|A0A7P0Z4F9|A0A7P0Z4F9_HUMAN" 4 2153.0773 0.82 133584 15672 4 2153.079433 539.2766 Double-stranded RNA-specific adenosine deaminase OS=Homo sapiens OX=9606 GN=ADAR PE=1 SV=4 6 2884.3 - 59769.1 - - - 0.9874 - 1.127 0.389 - 19.3 1 2 1 0.0021 19 0 0 0 1.29E+06 1.57E+06 - - - 2.6517 1 221125_WJC_METTL3_EV_vs_WT_F09.15676.15676.3 3.31E-13 18/84 K.DHTPSQELALTQSVGGDSSADR[166.11].L "sp|Q86U44|MTA70_HUMAN,tr|H0YFV6|H0YFV6_HUMAN" 2 2280.0494 0.08 133586 15676 3 2280.048208 761.0237 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 4.22 2884.8 - 221679 - - - -0.5083 - 4.142 0.688 - 345.9 1 2 0 -0.0012 22 0 0 0 1.39E+06 1.71E+07 - - - 9.5796 0.9997 221125_WJC_METTL3_EV_vs_WT_F09.15702.15702.2 0.00523 16-Aug K.TLLDIDNTR.M sp|P35527|K1C9_HUMAN 1 1059.556 98.05 133599 15702 2 1059.556087 530.7853 "Keratin, type I cytoskeletal 9 OS=Homo sapiens OX=9606 GN=KRT9 PE=1 SV=3" 4.21 2888.6 - 158297 - - - 0.0462 - 1.507 0.434 - 216.9 1 2 0 0 9 0 0 0 8.22E+06 8.38E+04 - - - 3.433 1 221125_WJC_METTL3_EV_vs_WT_F09.15703.15703.3 4.51E-09 17/72 K.TC[160.03]R[166.11]PSTQSAQIESLLNNNK[136.11].Q sp|Q10469|MGAT2_HUMAN 1 2178.0818 1.42 133600 15703 3 2178.08 727.0345 "Alpha-1,6-mannosyl-glycoprotein 2-beta-N-acetylglucosaminyltransferase OS=Homo sapiens OX=9606 GN=MGAT2 PE=1 SV=1" 7.89 2888.7 - 69774.6 - - - -0.8264 - 3.683 0.646 - 512.1 1 2 0 -0.0018 19 0 0 0 2.99E+07 2.11E+07 - - - 8.9448 1 221125_WJC_METTL3_EV_vs_WT_F09.15707.15707.3 4.41E-08 16/72 K.TC[160.03]RPSTQSAQIESLLNNNK.Q sp|Q10469|MGAT2_HUMAN 1 2160.0593 1.42 133602 15707 3 2160.060716 721.0271 "Alpha-1,6-mannosyl-glycoprotein 2-beta-N-acetylglucosaminyltransferase OS=Homo sapiens OX=9606 GN=MGAT2 PE=1 SV=1" 7.89 2889.3 - 137741 - - - 0.6416 - 3.078 0.647 - 430.3 1 2 0 0.0014 19 0 0 0 2.99E+07 2.11E+07 - - - 8.5152 0.9996 221125_WJC_METTL3_EV_vs_WT_F09.15721.15721.3 4.21E-05 6/108 R.GGPPGQFHDNANGGQNGTVQEIMIPAGK[136.11].A "sp|Q92945|FUBP2_HUMAN,tr|M0R0I5|M0R0I5_HUMAN,tr|M0QYH3|M0QYH3_HUMAN,tr|M0R0C6|M0R0C6_HUMAN,tr|M0QXW7|M0QXW7_HUMAN,tr|A0A087WTP3|A0A087WTP3_HUMAN" 6 2798.3286 1.27 133610 15721 3 2798.332658 933.7835 Far upstream element-binding protein 2 OS=Homo sapiens OX=9606 GN=KHSRP PE=1 SV=4 5.32 2891.2 - 112083 - - - 1.4591 - 1.443 0.446 - 17.5 1 2 0 0.0041 28 0 0 0 8.84E+06 6.96E+06 - - - 4.355 0.9998 221125_WJC_METTL3_EV_vs_WT_F09.15733.15733.3 9.40E-10 12/100 K.SEPVK[136.11]EESSELEQPFAQDTSSVGPDR[166.11].K "sp|Q14151|SAFB2_HUMAN,sp|Q15424|SAFB1_HUMAN" 2 2865.3271 1.63 133619 15733 3 2865.33464 956.1163 Scaffold attachment factor B2 OS=Homo sapiens OX=9606 GN=SAFB2 PE=1 SV=1 4 2892.9 - 94870.6 - - - 2.6276 - 2.88 0.56 - 108.3 1 2 1 0.0075 26 0 0 0 1.82E+07 1.12E+07 - - - 7.215 0.9983 221125_WJC_METTL3_EV_vs_WT_F09.15739.15739.3 0.0133 May-56 R.STSHK[136.11]PDEIYGMIER[166.11].L sp|Q86U44|MTA70_HUMAN 1 1779.8581 0.03 133622 15739 3 1779.859508 594.2933 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 5.42 2893.7 - 55360 - - - 0.8169 - 1.154 0.362 - 30 1 2 0 0.0015 15 0 0 0 1.99E+05 7.55E+06 - - - 2.9493 1 221125_WJC_METTL3_EV_vs_WT_F09.15744.15744.3 1.31E-07 17/100 K.SEPVKEESSELEQPFAQDTSSVGPDR.K "sp|Q14151|SAFB2_HUMAN,sp|Q15424|SAFB1_HUMAN" 2 2847.3046 1.64 133625 15744 3 2847.304675 950.1088 Scaffold attachment factor B2 OS=Homo sapiens OX=9606 GN=SAFB2 PE=1 SV=1 4 2894.4 - 205685 - - - 0.0119 - 3.483 0.606 - 206.8 1 2 1 0 26 0 0 0 1.83E+07 1.12E+07 - - - 8.1672 0.9995 221125_WJC_METTL3_EV_vs_WT_F09.15771.15771.3 0.000414 Aug-52 K.K[136.11]GPGEVAGTVTGQK[136.11].R "sp|Q86U44|MTA70_HUMAN,tr|F5H6D8|F5H6D8_HUMAN,tr|H0YFV6|H0YFV6_HUMAN,tr|B4DTN4|B4DTN4_HUMAN" 4 1343.738 0 133639 15771 3 1343.741286 448.9199 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 8.59 2898.3 - 78805 - - - 2.461 - 1.717 0.411 - 82.1 1 2 0 0.0033 14 0 0 0 1.43E+04 4.82E+06 - - - 4.5579 0.9995 221125_WJC_METTL3_EV_vs_WT_F09.15780.15780.4 0.0939 6/132 K.HGEVC[160.03]PAGWKPGSETIIPDPAGK.L sp|Q13162|PRDX4_HUMAN 1 2402.1689 0.72 133644 15780 4 2402.172087 601.5495 Peroxiredoxin-4 OS=Homo sapiens OX=9606 GN=PRDX4 PE=1 SV=1 5.45 2899.6 - 64469.1 - - - 1.335 - 1.077 0.364 - 22.1 1 2 0 0.0032 23 0 0 0 6.60E+06 9.19E+06 - - - 2.4174 0.9927 221125_WJC_METTL3_EV_vs_WT_F09.15786.15786.3 0.225 Jun-52 K.LGKDAVEDLESVGK.G sp|P81605|DCD_HUMAN 1 1458.7566 38.84 133648 15786 3 1458.755162 487.2595 Dermcidin OS=Homo sapiens OX=9606 GN=DCD PE=1 SV=2 4.32 2900.4 - 39924.1 - - - -0.9782 - 1.169 0.361 - 31.8 1 2 1 -0.0014 14 0 0 0 1.50E+06 3.86E+04 - - - 2.9794 1 221125_WJC_METTL3_EV_vs_WT_F09.15809.15809.4 3.26E-07 13/132 K.HGEVC[160.03]PAGWK[136.11]PGSETIIPDPAGK[136.11].L sp|Q13162|PRDX4_HUMAN 1 2418.1973 0.72 133660 15809 4 2418.202676 605.5566 Peroxiredoxin-4 OS=Homo sapiens OX=9606 GN=PRDX4 PE=1 SV=1 5.45 2903.8 - 206410 - - - 2.2314 - 2.606 0.565 - 87.8 1 2 0 0.0054 23 0 0 0 6.63E+06 9.19E+06 - - - 4.4526 0.9874 221125_WJC_METTL3_EV_vs_WT_F09.15822.15822.3 0.442 May-88 K.HGEVC[160.03]PAGWKPGSETIIPDPAGK.L sp|Q13162|PRDX4_HUMAN 1 2402.1689 0.64 133671 15822 3 2402.173576 801.7302 Peroxiredoxin-4 OS=Homo sapiens OX=9606 GN=PRDX4 PE=1 SV=1 5.45 2905.5 - 34989.4 - - - 1.9549 - 0.957 0.324 - 16.7 1 2 0 0.0047 23 0 0 0 1.29E+06 2.03E+06 - - - 2.0479 0.9998 221125_WJC_METTL3_EV_vs_WT_F09.15827.15827.3 8.55E-05 Jul-88 K.HGEVC[160.03]PAGWK[136.11]PGSETIIPDPAGK[136.11].L sp|Q13162|PRDX4_HUMAN 1 2418.1973 1.12 133673 15827 3 2418.1971 807.073 Peroxiredoxin-4 OS=Homo sapiens OX=9606 GN=PRDX4 PE=1 SV=1 5.45 2906.3 - 62374.8 - - - -0.0744 - 1.575 0.46 - 39 1 2 0 -0.0002 23 0 0 0 2.67E+06 2.39E+06 - - - 4.7342 0.9999 221125_WJC_METTL3_EV_vs_WT_F09.15830.15830.4 1.41E-05 10/108 R.FQSSHHPTDITSLDQYVER[166.11].M "sp|P14625|ENPL_HUMAN,tr|A0A7P0T917|A0A7P0T917_HUMAN,tr|A0A7P0T823|A0A7P0T823_HUMAN,tr|A0A7P0TAE1|A0A7P0TAE1_HUMAN,tr|H0YIV0|H0YIV0_HUMAN,tr|A0A7P0TAY2|A0A7P0TAY2_HUMAN,tr|A0A087WT78|A0A087WT78_HUMAN,tr|A0A7P0TAT8|A0A7P0TAT8_HUMAN" 8 2269.0639 0.98 133674 15830 4 2269.059132 568.2733 Endoplasmin OS=Homo sapiens OX=9606 GN=HSP90B1 PE=1 SV=1 5.21 2906.7 - 62634.4 - - - -2.0991 - 2.296 0.471 - 80.5 1 2 0 -0.0048 19 0 0 0 3.71E+06 3.79E+06 - - - 3.6054 0.9994 221125_WJC_METTL3_EV_vs_WT_F09.15831.15831.2 6.70E-05 24-Jul R.TTPSYVAFTDTER[166.11].L "sp|P48741|HSP77_HUMAN,sp|P54652|HSP72_HUMAN,sp|P0DMV8|HS71A_HUMAN,sp|P34931|HS71L_HUMAN,sp|P11142|HSP7C_HUMAN,sp|P0DMV9|HS71B_HUMAN,sp|P17066|HSP76_HUMAN,tr|E9PQQ4|E9PQQ4_HUMAN,tr|E9PNE6|E9PNE6_HUMAN,tr|E9PKE3|E9PKE3_HUMAN,tr|E9PLF4|E9PLF4_HUMAN,tr|Q53FA3|Q53FA3_HUMAN,tr|E9PI65|E9PI65_HUMAN,tr|E9PK54|E9PK54_HUMAN,tr|E9PN25|E9PN25_HUMAN,tr|E9PPY6|E9PPY6_HUMAN,tr|E9PQK7|E9PQK7_HUMAN,tr|A0A0G2JIW1|A0A0G2JIW1_HUMAN" 18 1496.7023 0.13 133675 15831 2 1496.703305 749.3584 Putative heat shock 70 kDa protein 7 OS=Homo sapiens OX=9606 GN=HSPA7 PE=5 SV=2 4.37 2906.8 - 55437.8 - - - 0.6989 - 1.799 0.338 - 157.1 1 2 0 0.001 13 0 0 0 8.40E+05 6.48E+06 - - - 3.0443 1 221125_WJC_METTL3_EV_vs_WT_F09.15838.15838.4 0.000371 12/108 R.FQSSHHPTDITSLDQYVER.M "sp|P14625|ENPL_HUMAN,tr|A0A7P0T917|A0A7P0T917_HUMAN,tr|A0A7P0T823|A0A7P0T823_HUMAN,tr|A0A7P0TAE1|A0A7P0TAE1_HUMAN,tr|H0YIV0|H0YIV0_HUMAN,tr|A0A7P0TAY2|A0A7P0TAY2_HUMAN,tr|A0A087WT78|A0A087WT78_HUMAN,tr|A0A7P0TAT8|A0A7P0TAT8_HUMAN" 8 2259.0556 0.97 133680 15838 4 2259.056273 565.7712 Endoplasmin OS=Homo sapiens OX=9606 GN=HSP90B1 PE=1 SV=1 5.21 2907.8 - 158372 - - - 0.2868 - 2.593 0.537 - 105 1 2 0 0.0006 19 0 0 0 3.71E+06 3.84E+06 - - - 4.2222 1 221125_WJC_METTL3_EV_vs_WT_F09.15847.15847.3 2.89E-10 Dec-72 R.FQSSHHPTDITSLDQYVER[166.11].M "sp|P14625|ENPL_HUMAN,tr|A0A7P0T917|A0A7P0T917_HUMAN,tr|A0A7P0T823|A0A7P0T823_HUMAN,tr|A0A7P0TAE1|A0A7P0TAE1_HUMAN,tr|H0YIV0|H0YIV0_HUMAN,tr|A0A7P0TAY2|A0A7P0TAY2_HUMAN,tr|A0A087WT78|A0A087WT78_HUMAN,tr|A0A7P0TAT8|A0A7P0TAT8_HUMAN" 8 2269.0639 0.86 133687 15847 3 2269.067451 757.3619 Endoplasmin OS=Homo sapiens OX=9606 GN=HSP90B1 PE=1 SV=1 5.21 2909 - 94143.9 - - - 1.5672 - 2.564 0.647 - 135.5 1 2 0 0.0036 19 0 0 0 1.15E+06 1.34E+06 - - - 8.0657 1 221125_WJC_METTL3_EV_vs_WT_F09.15852.15852.3 7.30E-07 Oct-72 R.FQSSHHPTDITSLDQYVER.M "sp|P14625|ENPL_HUMAN,tr|A0A7P0T917|A0A7P0T917_HUMAN,tr|A0A7P0T823|A0A7P0T823_HUMAN,tr|A0A7P0TAE1|A0A7P0TAE1_HUMAN,tr|H0YIV0|H0YIV0_HUMAN,tr|A0A7P0TAY2|A0A7P0TAY2_HUMAN,tr|A0A087WT78|A0A087WT78_HUMAN,tr|A0A7P0TAT8|A0A7P0TAT8_HUMAN" 8 2259.0556 0.86 133690 15852 3 2259.055602 754.0258 Endoplasmin OS=Homo sapiens OX=9606 GN=HSP90B1 PE=1 SV=1 5.21 2909.7 - 137940 - - - -0.0102 - 2.272 0.548 - 128.5 1 2 0 0 19 0 0 0 1.15E+06 1.34E+06 - - - 6.6659 0.9993 221125_WJC_METTL3_EV_vs_WT_F09.15854.15854.3 0.00111 Jun-52 K.SFFDNISC[160.03]DDNR[166.11]ER[166.11].R "sp|Q8ND56|LS14A_HUMAN,tr|A0A096LP11|A0A096LP11_HUMAN,tr|A0A140TA76|A0A140TA76_HUMAN,tr|A0A0G2JQ95|A0A0G2JQ95_HUMAN" 4 1793.7542 1.07 133692 15854 3 1793.75533 598.9253 Protein LSM14 homolog A OS=Homo sapiens OX=9606 GN=LSM14A PE=1 SV=3 4.23 2910 - 61402.9 - - - 0.6294 - 1.566 0.456 - 32.1 1 2 1 0.0011 14 0 0 0 6.01E+06 5.63E+06 - - - 4.8156 0.9155 221125_WJC_METTL3_EV_vs_WT_F09.15858.15858.4 0.512 Jul-72 R.C[160.03]ILPFDKETGFHR.G "sp|Q9GZT3|SLIRP_HUMAN,tr|H0YJW7|H0YJW7_HUMAN,tr|A0A087WUN7|A0A087WUN7_HUMAN,tr|G3V2S9|G3V2S9_HUMAN,tr|H0YJ40|H0YJ40_HUMAN,tr|G3V4X6|G3V4X6_HUMAN" 6 1618.7926 1.26 133696 15858 4 1618.793612 405.7054 "SRA stem-loop-interacting RNA-binding protein, mitochondrial OS=Homo sapiens OX=9606 GN=SLIRP PE=1 SV=1" 6.74 2910.5 - 38989.1 - - - 0.627 - 1.347 0.178 - 47.2 1 2 1 0.001 13 0 0 0 8.86E+05 7.01E+05 - - - 0.8855 0.9999 221125_WJC_METTL3_EV_vs_WT_F09.15868.15868.3 2.00E-05 Oct-52 K.SFFDNISC[160.03]DDNRER.R "sp|Q8ND56|LS14A_HUMAN,tr|A0A096LP11|A0A096LP11_HUMAN,tr|A0A140TA76|A0A140TA76_HUMAN,tr|A0A0G2JQ95|A0A0G2JQ95_HUMAN" 4 1773.7377 1.07 133702 15868 3 1773.73853 592.2532 Protein LSM14 homolog A OS=Homo sapiens OX=9606 GN=LSM14A PE=1 SV=3 4.23 2912 - 116332 - - - 0.4899 - 1.779 0.639 - 103.1 1 2 1 0.0009 14 0 0 0 6.01E+06 5.63E+06 - - - 7.1948 0.9986 221125_WJC_METTL3_EV_vs_WT_F09.15869.15869.3 9.36E-09 15/96 F.GTETSNSGTLPQSSAVGSAFTQDTR[166.11].S "sp|Q8ND56|LS14A_HUMAN,tr|A0A140TA76|A0A140TA76_HUMAN,tr|K7EMZ9|K7EMZ9_HUMAN" 3 2508.1604 1.03 133703 15869 3 2508.163121 837.0607 Protein LSM14 homolog A OS=Homo sapiens OX=9606 GN=LSM14A PE=1 SV=3 4.37 2912.1 - 205128 - - - 1.0952 - 3.044 0.623 - 164.1 1 1 0 0.0027 25 0 0 0 2.73E+07 2.64E+07 - - - 8.0461 0.9989 221125_WJC_METTL3_EV_vs_WT_F09.15870.15870.3 3.47E-05 16/96 F.GTETSNSGTLPQSSAVGSAFTQDTR.S "sp|Q8ND56|LS14A_HUMAN,tr|A0A140TA76|A0A140TA76_HUMAN,tr|K7EMZ9|K7EMZ9_HUMAN" 3 2498.1521 1.03 133704 15870 3 2498.154195 833.7246 Protein LSM14 homolog A OS=Homo sapiens OX=9606 GN=LSM14A PE=1 SV=3 4.37 2912.2 - 176905 - - - 0.837 - 3.276 0.63 - 213.5 1 1 0 0.0021 25 0 0 0 2.73E+07 2.64E+07 - - - 8.2933 0.9896 221125_WJC_METTL3_EV_vs_WT_F09.15871.15871.3 0.171 May-76 R.QQVAFYGQTLGQAQAHSQEQ.- sp|Q96I24|FUBP3_HUMAN 1 2218.0403 - 133705 15871 3 2218.040355 740.354 Far upstream element-binding protein 3 OS=Homo sapiens OX=9606 GN=FUBP3 PE=1 SV=2 5.24 2912.4 - 103073 - - - 0.0207 - 1.304 0.233 - 20.8 1 2 0 0 20 0 0 0 - - - - - 1.7817 0.8194 221125_WJC_METTL3_EV_vs_WT_F09.15882.15882.3 8.08 May-48 R.TTPSYVAFTDTER[166.11].L "sp|P48741|HSP77_HUMAN,sp|P54652|HSP72_HUMAN,sp|P0DMV8|HS71A_HUMAN,sp|P34931|HS71L_HUMAN,sp|P11142|HSP7C_HUMAN,sp|P0DMV9|HS71B_HUMAN,sp|P17066|HSP76_HUMAN,tr|E9PQQ4|E9PQQ4_HUMAN,tr|E9PNE6|E9PNE6_HUMAN,tr|E9PKE3|E9PKE3_HUMAN,tr|E9PLF4|E9PLF4_HUMAN,tr|Q53FA3|Q53FA3_HUMAN,tr|E9PI65|E9PI65_HUMAN,tr|E9PK54|E9PK54_HUMAN,tr|E9PN25|E9PN25_HUMAN,tr|E9PPY6|E9PPY6_HUMAN,tr|E9PQK7|E9PQK7_HUMAN,tr|A0A0G2JIW1|A0A0G2JIW1_HUMAN" 18 1496.7023 0.05 133711 15882 3 1496.703747 499.908 Putative heat shock 70 kDa protein 7 OS=Homo sapiens OX=9606 GN=HSPA7 PE=5 SV=2 4.37 2913.8 - 25883.9 - - - 0.9942 - 1.144 0.11 - 32.6 1 2 0 0.0015 13 0 0 0 2.96E+04 5.90E+05 - - - 0.1307 0.9997 221125_WJC_METTL3_EV_vs_WT_F09.15893.15893.4 0.00828 7/192 R.ITPEPAVSNTEEPSTTSTASNYPDVLTRPSLHR.S sp|P49790|NU153_HUMAN 1 3566.7489 2.33 133720 15893 4 3566.744364 892.6945 Nuclear pore complex protein Nup153 OS=Homo sapiens OX=9606 GN=NUP153 PE=1 SV=2 4.83 2915.2 - 58531.1 - - - -1.2675 - 1.537 0.377 - 25.7 1 2 0 -0.0045 33 0 0 0 1.00E+06 4.31E+05 - - - 2.6351 1 221125_WJC_METTL3_EV_vs_WT_F09.15897.15897.3 7.90E-08 13/56 K.QISNLQQSISDAEQR.G sp|P04264|K2C1_HUMAN 1 1715.8438 12.66 133722 15897 3 1715.845261 572.9552 "Keratin, type II cytoskeletal 1 OS=Homo sapiens OX=9606 GN=KRT1 PE=1 SV=6" 4.37 2915.8 - 143006 - - - 0.8276 - 2.937 0.569 - 243.2 1 2 0 0.0014 15 0 0 0 8.71E+06 6.88E+05 - - - 7.6947 1 221125_WJC_METTL3_EV_vs_WT_F09.15899.15899.3 6.31E-08 13/52 K.HWPFQVINDGDK[136.11]PK[136.11].V "sp|P0DMV8|HS71A_HUMAN,sp|P0DMV9|HS71B_HUMAN,tr|A0A0G2JIW1|A0A0G2JIW1_HUMAN" 3 1695.8704 0.11 133724 15899 3 1695.868634 566.2974 Heat shock 70 kDa protein 1A OS=Homo sapiens OX=9606 GN=HSPA1A PE=1 SV=1 6.75 2916.1 - 142141 - - - -1.0355 - 2.299 0.614 - 242.4 1 2 0 -0.0018 14 0 0 0 1.59E+07 1.49E+08 - - - 7.5973 0.9923 221125_WJC_METTL3_EV_vs_WT_F09.15906.15906.3 0.00891 May-80 K.KVDKIEELDQENEAALENGIK.N "sp|P43243|MATR3_HUMAN,tr|B3KM87|B3KM87_HUMAN,tr|A8MXP9|A8MXP9_HUMAN,tr|A0A0R4J2E8|A0A0R4J2E8_HUMAN,tr|D6REM6|D6REM6_HUMAN" 5 2384.2071 1.64 133728 15906 3 2384.206031 795.743 Matrin-3 OS=Homo sapiens OX=9606 GN=MATR3 PE=1 SV=2 4.25 2917 - 75441.2 - - - -0.4479 - 1.514 0.306 - 17.1 1 2 1 -0.0011 21 0 0 0 2.78E+06 1.70E+06 - - - 2.9457 1 221125_WJC_METTL3_EV_vs_WT_F09.15911.15911.3 3.04E-11 17/84 K.DHTPSQELALTQSVGGDSSADR[166.11].L "sp|Q86U44|MTA70_HUMAN,tr|H0YFV6|H0YFV6_HUMAN" 2 2280.0494 0 133731 15911 3 2281.047326 761.0237 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 4.22 2917.7 - 242486 - - - 437.6918 - 3.814 0.671 - 322.7 1 2 0 0.998 22 0 0 0 5.14E+04 2.83E+07 - - - 8.9183 0.9505 221125_WJC_METTL3_EV_vs_WT_F09.15915.15915.4 0.164 Jun-78 K.HWPFQVINDGDK[136.11]PK[136.11].V "sp|P0DMV8|HS71A_HUMAN,sp|P0DMV9|HS71B_HUMAN,tr|A0A0G2JIW1|A0A0G2JIW1_HUMAN" 3 1695.8704 0.11 133733 15915 4 1695.869486 424.9749 Heat shock 70 kDa protein 1A OS=Homo sapiens OX=9606 GN=HSPA1A PE=1 SV=1 6.75 2918.3 - 80462.9 - - - -0.5331 - 1.207 0.179 - 23.1 2 2 0 -0.0009 14 0 0 0 4.20E+06 3.85E+07 - - - 0.6228 1 221125_WJC_METTL3_EV_vs_WT_F09.15921.15921.2 4.82E-09 13/28 K.QISNLQQSISDAEQR.G sp|P04264|K2C1_HUMAN 1 1715.8438 2.39 133736 15921 2 1715.840842 858.9292 "Keratin, type II cytoskeletal 1 OS=Homo sapiens OX=9606 GN=KRT1 PE=1 SV=6" 4.37 2919 - 180001 - - - -1.7478 - 2.756 0.603 - 627.4 1 2 0 -0.003 15 0 0 0 5.24E+06 2.19E+06 - - - 5.9862 1 221125_WJC_METTL3_EV_vs_WT_F09.15926.15926.3 3.64E-06 15/108 K.GDSGVDTQNSEGNADEEDPLGPNC[160.03]YYDK.T "sp|Q8ND56|LS14A_HUMAN,tr|A0A096LP11|A0A096LP11_HUMAN,tr|A0A140TA76|A0A140TA76_HUMAN,tr|K7EMZ9|K7EMZ9_HUMAN,tr|A0A0G2JQ95|A0A0G2JQ95_HUMAN" 5 3045.2054 1.16 133739 15926 3 3045.199346 1016.0757 Protein LSM14 homolog A OS=Homo sapiens OX=9606 GN=LSM14A PE=1 SV=3 3.54 2919.7 - 209044 - - - -1.9874 - 2.957 0.768 - 155.7 1 2 0 -0.0061 28 0 0 0 3.47E+07 3.00E+07 - - - 9.5951 0.9993 221125_WJC_METTL3_EV_vs_WT_F09.15931.15931.4 0.0428 9/174 K.QPTEEEASSKEDSAPSKPVVGIIYPPPEVR.N "sp|Q15459|SF3A1_HUMAN,tr|F8WB66|F8WB66_HUMAN" 2 3235.6249 1.52 133741 15931 4 3235.627257 809.9135 Splicing factor 3A subunit 1 OS=Homo sapiens OX=9606 GN=SF3A1 PE=1 SV=1 4.42 2920.4 - 164932 - - - 0.743 - 1.762 0.4 - 32.1 1 2 1 0.0024 30 0 0 0 9.01E+06 5.94E+06 - - - 2.8803 0.9999 221125_WJC_METTL3_EV_vs_WT_F09.15970.15970.3 1.02E-05 Oct-52 K.HWPFQVINDGDKPK.V "sp|P0DMV8|HS71A_HUMAN,sp|P0DMV9|HS71B_HUMAN,tr|A0A0G2JIW1|A0A0G2JIW1_HUMAN" 3 1679.842 0.11 133766 15970 3 1679.838585 560.9546 Heat shock 70 kDa protein 1A OS=Homo sapiens OX=9606 GN=HSPA1A PE=1 SV=1 6.75 2925.3 - 85256.2 - - - -2.027 - 2.042 0.516 - 111.1 1 2 0 -0.0034 14 0 0 0 1.58E+07 1.49E+08 - - - 6.1892 0.9965 221125_WJC_METTL3_EV_vs_WT_F09.15979.15979.4 0.000648 8/174 K.QPTEEEASSK[136.11]EDSAPSK[136.11]PVVGIIYPPPEVR[166.11].N "sp|Q15459|SF3A1_HUMAN,tr|F8WB66|F8WB66_HUMAN" 2 3261.6615 1.45 133769 15979 4 3261.659615 816.4227 Splicing factor 3A subunit 1 OS=Homo sapiens OX=9606 GN=SF3A1 PE=1 SV=1 4.42 2926.6 - 148729 - - - -0.585 - 1.952 0.307 - 26.5 1 2 1 -0.0019 30 0 0 0 8.60E+06 5.94E+06 - - - 2.1023 0.986 221125_WJC_METTL3_EV_vs_WT_F09.15984.15984.2 0.333 14-Jun R.NLLSVAYK.N "sp|P31946|1433B_HUMAN,sp|P62258|1433E_HUMAN,sp|P27348|1433T_HUMAN,sp|P63104|1433Z_HUMAN,sp|Q04917|1433F_HUMAN,sp|P31947|1433S_HUMAN,sp|P61981|1433G_HUMAN,tr|E7EX29|E7EX29_HUMAN,tr|Q4VY19|Q4VY19_HUMAN,tr|B4DJF2|B4DJF2_HUMAN,tr|A0A0J9YWZ2|A0A0J9YWZ2_HUMAN,tr|Q4VY20|Q4VY20_HUMAN,tr|A2IDB2|A2IDB2_HUMAN,tr|E5RIR4|E5RIR4_HUMAN,tr|E9PG15|E9PG15_HUMAN,tr|I3L3T1|I3L3T1_HUMAN,tr|K7EIT4|K7EIT4_HUMAN,tr|E7EVZ2|E7EVZ2_HUMAN,tr|E5RGE1|E5RGE1_HUMAN,tr|E9PD24|E9PD24_HUMAN,tr|A0A0J9YWE8|A0A0J9YWE8_HUMAN,tr|E7ESK7|E7ESK7_HUMAN" 22 906.5175 28.6 133772 15984 2 906.515335 454.266 14-3-3 protein beta\alpha OS=Homo sapiens OX=9606 GN=YWHAB PE=1 SV=3 8.59 2927.3 - 104011 - - - -2.353 - 1.181 0.21 - 127.3 1 2 0 -0.0021 8 0 0 0 7.33E+06 2.56E+05 - - - 1.0931 0.9994 221125_WJC_METTL3_EV_vs_WT_F09.16078.16078.3 7.28E-05 Jul-52 K.K[136.11]GPGEVAGTVTGQK[136.11].R "sp|Q86U44|MTA70_HUMAN,tr|F5H6D8|F5H6D8_HUMAN,tr|H0YFV6|H0YFV6_HUMAN,tr|B4DTN4|B4DTN4_HUMAN" 4 1343.738 0 133799 16078 3 1343.732995 448.9199 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 8.59 2941.2 - 140742 - - - -3.7091 - 1.863 0.454 - 59.3 1 2 0 -0.005 14 0 0 0 2.87E+04 1.24E+07 - - - 5.2538 0.9121 221125_WJC_METTL3_EV_vs_WT_F09.16094.16094.3 0.00306 Jul-76 K.HAASDVDLEIESLLNQQSTK[136.11].E "sp|Q86U44|MTA70_HUMAN,tr|F5H6D8|F5H6D8_HUMAN,tr|H0YFV6|H0YFV6_HUMAN,tr|B4DTN4|B4DTN4_HUMAN" 4 2205.1005 0.02 133807 16094 3 2206.094691 736.0408 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 4.31 2943.2 - 102553 - - - 450.8797 - 1.544 0.422 - 47.5 1 2 0 0.9942 20 0 0 0 1.74E+04 7.75E+05 - - - 4.0233 1 221125_WJC_METTL3_EV_vs_WT_F09.16111.16111.4 5.59E-11 16/180 R.PC[160.03]LQPC[160.03]EHPEPC[160.03]PRPEPIPLPAPC[160.03]PSPEPC[160.03]R.E sp|Q5T749|KPRP_HUMAN 1 3670.6612 999 133813 16111 4 3670.647801 918.6726 Keratinocyte proline-rich protein OS=Homo sapiens OX=9606 GN=KPRP PE=1 SV=1 4.91 2945.5 - 251076 - - - -3.6383 - 3.386 0.685 - 99 1 1 0 -0.0134 31 0 0 0 5.42E+06 0.00E+00 - - - 5.5552 1 221125_WJC_METTL3_EV_vs_WT_F09.16116.16116.3 0.000314 23/52 K.HWPFQVINDGDK[136.11]PK[136.11].V "sp|P0DMV8|HS71A_HUMAN,sp|P0DMV9|HS71B_HUMAN,tr|A0A0G2JIW1|A0A0G2JIW1_HUMAN" 3 1695.8704 0.11 133816 16116 3 1695.867221 566.2974 Heat shock 70 kDa protein 1A OS=Homo sapiens OX=9606 GN=HSPA1A PE=1 SV=1 6.75 2946.2 - 1.32E+06 - - - -1.8687 - 3.626 0.555 - 996.7 1 2 0 -0.0032 14 0 0 0 1.59E+07 1.49E+08 - - - 8.1501 0.8676 221125_WJC_METTL3_EV_vs_WT_F09.16130.16130.3 0.0708 Apr-32 K.FYVHNDIFR.Y "sp|Q13283|G3BP1_HUMAN,tr|A0A7I2V5M7|A0A7I2V5M7_HUMAN,tr|A0A7P0P2U7|A0A7P0P2U7_HUMAN,tr|A0A7I2YQU8|A0A7I2YQU8_HUMAN,tr|A0A7I2V651|A0A7I2V651_HUMAN,tr|A0A7I2YQN9|A0A7I2YQN9_HUMAN,tr|A0A7I2V2V1|A0A7I2V2V1_HUMAN" 7 1209.5931 1.25 133824 16130 3 1209.592703 404.205 Ras GTPase-activating protein-binding protein 1 OS=Homo sapiens OX=9606 GN=G3BP1 PE=1 SV=1 6.74 2948.1 - 50336.5 - - - -0.3224 - 0.897 0.185 - 19.2 1 2 0 -0.0004 9 0 0 0 8.18E+05 6.53E+05 - - - 0.2749 1 221125_WJC_METTL3_EV_vs_WT_F09.16133.16133.4 2.05E-08 15/78 K.HWPFQVINDGDK[136.11]PK[136.11].V "sp|P0DMV8|HS71A_HUMAN,sp|P0DMV9|HS71B_HUMAN,tr|A0A0G2JIW1|A0A0G2JIW1_HUMAN" 3 1695.8704 0.11 133825 16133 4 1695.86682 424.9749 Heat shock 70 kDa protein 1A OS=Homo sapiens OX=9606 GN=HSPA1A PE=1 SV=1 6.75 2948.5 - 274439 - - - -2.1051 - 2.643 0.632 - 161.9 1 2 0 -0.0036 14 0 0 0 4.18E+06 3.85E+07 - - - 5.0797 0.9931 221125_WJC_METTL3_EV_vs_WT_F09.16136.16136.3 8.52E-05 9/112 P.VPTAPTSGGPK[136.11]PSTASAVPELATDPELEK[136.11].K "sp|Q86U44|MTA70_HUMAN,tr|B4E349|B4E349_HUMAN,tr|F5H6D8|F5H6D8_HUMAN,tr|H0YFV6|H0YFV6_HUMAN,tr|B4DTN4|B4DTN4_HUMAN" 5 2862.4833 0.001 133827 16136 3 2862.479932 955.1684 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 4.41 2948.8 - 119276 - - - -1.1885 - 2.236 0.476 - 39.4 1 1 0 -0.0034 29 0 0 0 0.00E+00 3.38E+06 - - - 5.6973 0.8626 221125_WJC_METTL3_EV_vs_WT_F09.16142.16142.4 0.137 7/144 R.EGDRSPSEDEFLSC[160.03]DSSSDR[166.11]GEGDG.Q sp|Q9Y2K6|UBP20_HUMAN 1 2699.0401 - 133831 16142 4 2699.04629 675.7673 Ubiquitin carboxyl-terminal hydrolase 20 OS=Homo sapiens OX=9606 GN=USP20 PE=1 SV=2 3.76 2949.6 - 235692 - - - 2.3079 - 1.367 0.409 - 19.6 1 1 2 0.0062 25 0 0 0 - - - - - 2.8837 0.8921 221125_WJC_METTL3_EV_vs_WT_F09.16168.16168.4 1.77 Jun-96 K.QVK[136.11]PYVEEGLHPQIIIR[166.11].A "sp|Q99832|TCPH_HUMAN,tr|F8WAM2|F8WAM2_HUMAN" 2 2036.1538 0.09 133845 16168 4 2036.154246 510.0457 T-complex protein 1 subunit eta OS=Homo sapiens OX=9606 GN=CCT7 PE=1 SV=2 6.76 2953.2 - 62371.2 - - - 0.2357 - 0.984 0.131 - 19.4 1 2 0 0.0005 17 0 0 0 2.20E+05 2.55E+06 - - - 0.3605 0.9663 221125_WJC_METTL3_EV_vs_WT_F09.16169.16169.4 0.0765 6/138 R.QDGSQEAPEAPLSSELEPFHPKPK.L "sp|Q14676|MDC1_HUMAN,tr|H0Y6Z8|H0Y6Z8_HUMAN" 2 2617.266 0.33 133846 16169 4 2617.273792 655.3238 Mediator of DNA damage checkpoint protein 1 OS=Homo sapiens OX=9606 GN=MDC1 PE=1 SV=3 4.57 2953.3 - 85721.9 - - - 2.9729 - 1.336 0.208 - 23.8 1 2 0 0.0078 24 0 0 0 2.31E+06 7.05E+06 - - - 1.1273 0.9957 221125_WJC_METTL3_EV_vs_WT_F09.16177.16177.4 0.0891 6/174 K.QPTEEEASSKEDSAPSKPVVGIIYPPPEVR.N "sp|Q15459|SF3A1_HUMAN,tr|F8WB66|F8WB66_HUMAN" 2 3235.6249 1.43 133852 16177 4 3235.623041 809.9135 Splicing factor 3A subunit 1 OS=Homo sapiens OX=9606 GN=SF3A1 PE=1 SV=1 4.42 2954.3 - 71002.3 - - - -0.56 - 1.402 0.309 - 15.4 1 2 1 -0.0018 30 0 0 0 5.77E+06 4.02E+06 - - - 2.0184 1 221125_WJC_METTL3_EV_vs_WT_F09.16182.16182.3 1.20E-11 19/84 K.DHTPSQELALTQSVGGDSSADR[166.11].L "sp|Q86U44|MTA70_HUMAN,tr|H0YFV6|H0YFV6_HUMAN" 2 2280.0494 0.01 133855 16182 3 2280.047163 761.0237 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 4.22 2955 - 274636 - - - -0.9666 - 3.755 0.693 - 339.8 1 2 0 -0.0022 22 0 0 0 2.48E+05 3.46E+07 - - - 9.4025 0.9976 221125_WJC_METTL3_EV_vs_WT_F09.16204.16204.4 0.00822 7/174 K.QPTEEEASSK[136.11]EDSAPSK[136.11]PVVGIIYPPPEVR[166.11].N "sp|Q15459|SF3A1_HUMAN,tr|F8WB66|F8WB66_HUMAN" 2 3261.6615 1.46 133868 16204 4 3261.661644 816.4227 Splicing factor 3A subunit 1 OS=Homo sapiens OX=9606 GN=SF3A1 PE=1 SV=1 4.42 2958.1 - 65766.6 - - - 0.0371 - 1.642 0.332 - 19.5 1 2 1 0.0001 30 0 0 0 1.92E+06 1.32E+06 - - - 2.2674 0.7678 221125_WJC_METTL3_EV_vs_WT_F09.16205.16205.3 3.57 3/108 R.KSEATPSPGAC[160.03]LQPEVPLSPAEQATTVK.A "sp|Q2NL68|PRSR3_HUMAN,tr|A0A2R8Y8D9|A0A2R8Y8D9_HUMAN" 2 2892.4539 4.75 133869 16205 3 2892.457448 965.1586 Proline and serine-rich protein 3 OS=Homo sapiens OX=9606 GN=PROSER3 PE=1 SV=1 4.79 2958.2 - 29191.4 - - - 1.2304 - 1 0.153 - 6.5 3 2 0 0.0036 28 0 0 0 5.07E+05 1.07E+05 - - - 0.024 0.9995 221125_WJC_METTL3_EV_vs_WT_F09.16214.16214.2 0.0349 22-Aug R.TVIIEQSWGSPK[136.11].V "sp|P10809|CH60_HUMAN,tr|C9JL25|C9JL25_HUMAN,tr|A0A7I2V2X6|A0A7I2V2X6_HUMAN,tr|A0A7I2YQK6|A0A7I2YQK6_HUMAN,tr|A0A7I2V599|A0A7I2V599_HUMAN,tr|E7EXB4|E7EXB4_HUMAN,tr|C9JL19|C9JL19_HUMAN,tr|A0A7I2YQ71|A0A7I2YQ71_HUMAN,tr|E7ESH4|E7ESH4_HUMAN,tr|A0A7I2V5M1|A0A7I2V5M1_HUMAN,tr|A0A7I2V5K3|A0A7I2V5K3_HUMAN,tr|A0A7I2V369|A0A7I2V369_HUMAN,tr|C9JCQ4|C9JCQ4_HUMAN" 13 1351.7227 1.24 133876 16214 2 1351.722943 676.8686 "60 kDa heat shock protein, mitochondrial OS=Homo sapiens OX=9606 GN=HSPD1 PE=1 SV=2" 5.66 2959.4 - 51874.1 - - - 0.1679 - 1.78 0.338 - 189.6 1 2 0 0.0002 12 0 0 0 1.94E+06 1.57E+06 - - - 3.0546 0.9999 221125_WJC_METTL3_EV_vs_WT_F09.16217.16217.3 1.43E-07 Sep-64 R.HDGSEPC[160.03]VDVLFGDGHR.L sp|Q96EL3|RM53_HUMAN 1 1895.8221 1.15 133879 16217 3 1895.828933 632.948 "39S ribosomal protein L53, mitochondrial OS=Homo sapiens OX=9606 GN=MRPL53 PE=1 SV=1" 4.64 2959.8 - 45245.7 - - - 3.6253 - 2.174 0.614 - 91.3 1 2 0 0.0069 17 0 0 0 5.38E+06 4.67E+06 - - - 7.3454 0.9992 221125_WJC_METTL3_EV_vs_WT_F09.16227.16227.2 0.0785 22-Jul R.TVIIEQSWGSPK.V "sp|P10809|CH60_HUMAN,tr|C9JL25|C9JL25_HUMAN,tr|A0A7I2V2X6|A0A7I2V2X6_HUMAN,tr|A0A7I2YQK6|A0A7I2YQK6_HUMAN,tr|A0A7I2V599|A0A7I2V599_HUMAN,tr|E7EXB4|E7EXB4_HUMAN,tr|C9JL19|C9JL19_HUMAN,tr|A0A7I2YQ71|A0A7I2YQ71_HUMAN,tr|E7ESH4|E7ESH4_HUMAN,tr|A0A7I2V5M1|A0A7I2V5M1_HUMAN,tr|A0A7I2V5K3|A0A7I2V5K3_HUMAN,tr|A0A7I2V369|A0A7I2V369_HUMAN,tr|C9JCQ4|C9JCQ4_HUMAN" 13 1343.7085 1.24 133885 16227 2 1343.707005 672.8615 "60 kDa heat shock protein, mitochondrial OS=Homo sapiens OX=9606 GN=HSPD1 PE=1 SV=2" 5.66 2961.3 - 62968.7 - - - -1.1245 - 1.704 0.321 - 149.9 1 2 0 -0.0015 12 0 0 0 1.94E+06 1.57E+06 - - - 2.8138 1 221125_WJC_METTL3_EV_vs_WT_F09.16236.16236.3 1.79E-09 Oct-64 R.HDGSEPC[160.03]VDVLFGDGHR[166.11].L sp|Q96EL3|RM53_HUMAN 1 1905.8303 1.16 133891 16236 3 1905.830362 636.2841 "39S ribosomal protein L53, mitochondrial OS=Homo sapiens OX=9606 GN=MRPL53 PE=1 SV=1" 4.64 2962.5 - 94562 - - - 0.0168 - 2.343 0.705 - 136.2 1 2 0 0 17 0 0 0 5.38E+06 4.66E+06 - - - 8.551 0.9744 221125_WJC_METTL3_EV_vs_WT_F09.16247.16247.4 0.0454 7/114 R.AISHEHSPSDLEAHFVPLVK[136.11].R "sp|P30153|2AAA_HUMAN,tr|C9J9C1|C9J9C1_HUMAN" 2 2220.1419 0.67 133898 16247 4 2220.148704 556.0427 Serine\threonine-protein phosphatase 2A 65 kDa regulatory subunit A alpha isoform OS=Homo sapiens OX=9606 GN=PPP2R1A PE=1 SV=4 5.75 2964 - 134850 - - - 3.0795 - 1.143 0.228 - 24.3 1 2 0 0.0068 20 0 0 0 3.75E+06 5.62E+06 - - - 1.2533 0.9926 221125_WJC_METTL3_EV_vs_WT_F09.16258.16258.3 0.0109 5/112 K.QK[136.11]GDTPASATAGDTLSVPAPAVQPEESLK[136.11].T "tr|A0A087WYS0|A0A087WYS0_HUMAN,tr|C9J406|C9J406_HUMAN,tr|H7C463|H7C463_HUMAN" 3 2880.4687 1.62 133906 16258 3 2880.467061 961.1635 MICOS complex subunit MIC60 OS=Homo sapiens OX=9606 GN=IMMT PE=1 SV=1 4.32 2965.6 - 101678 - - - -0.5853 - 1.208 0.359 - 10.6 1 2 1 -0.0017 29 0 0 0 3.18E+07 1.97E+07 - - - 2.9768 0.9792 221125_WJC_METTL3_EV_vs_WT_F09.16276.16276.2 0.122 16-Apr R.VLDELTLTK.A "sp|P13645|K1C10_HUMAN,tr|A0A1B0GVI3|A0A1B0GVI3_HUMAN" 2 1030.591 999 133919 16276 2 1030.592183 516.3028 "Keratin, type I cytoskeletal 10 OS=Homo sapiens OX=9606 GN=KRT10 PE=1 SV=6" 4.37 2968 - 71103.7 - - - 1.1217 - 0.877 0.229 - 37.9 1 2 0 0.0012 9 0 0 0 9.06E+06 0.00E+00 - - - 0.3523 0.9963 221125_WJC_METTL3_EV_vs_WT_F09.16279.16279.4 3.41E-05 Sep-96 R.HDGSEPC[160.03]VDVLFGDGHR[166.11].L sp|Q96EL3|RM53_HUMAN 1 1905.8303 1.48 133920 16279 4 1906.830994 477.4649 "39S ribosomal protein L53, mitochondrial OS=Homo sapiens OX=9606 GN=MRPL53 PE=1 SV=1" 4.64 2968.5 - 112442 - - - 525.0541 - 1.567 0.461 - 52.6 1 2 0 1.0007 17 0 0 0 2.75E+06 1.87E+06 - - - 3.1173 0.852 221125_WJC_METTL3_EV_vs_WT_F09.16284.16284.2 0.106 Apr-34 K.DHTPSQELALTQSVGGDS.S "sp|Q86U44|MTA70_HUMAN,tr|H0YFV6|H0YFV6_HUMAN" 2 1840.8439 - 133923 16284 2 1840.84124 921.4292 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 4.02 2969.2 - 57899.4 - - - -1.445 - 0.876 0.421 - 30.2 1 1 0 -0.0027 18 0 0 0 - - - - - 1.8242 0.8972 221125_WJC_METTL3_EV_vs_WT_F09.16303.16303.2 15.5 16-Apr R.AGLQFPVGR.V "sp|P16104|H2AX_HUMAN,sp|Q9BTM1|H2AJ_HUMAN,sp|Q93077|H2A1C_HUMAN,sp|Q99878|H2A1J_HUMAN,sp|Q16777|H2A2C_HUMAN,sp|Q8IUE6|H2A2B_HUMAN,sp|Q96QV6|H2A1A_HUMAN,sp|P0C0S5|H2AZ_HUMAN,sp|P04908|H2A1B_HUMAN,sp|P20671|H2A1D_HUMAN,sp|P0C0S8|H2A1_HUMAN,sp|Q6FI13|H2A2A_HUMAN,sp|Q96KK5|H2A1H_HUMAN,sp|Q71UI9|H2AV_HUMAN,sp|Q7L7L0|H2A3_HUMAN,tr|A0A0U1RR32|A0A0U1RR32_HUMAN,tr|A0A0U1RRH7|A0A0U1RRH7_HUMAN,tr|A0A3B3IS11|A0A3B3IS11_HUMAN,tr|C9J0D1|C9J0D1_HUMAN,tr|A0A494C189|A0A494C189_HUMAN" 20 943.524 1.19 133935 16303 2 943.523684 472.7693 Histone H2AX OS=Homo sapiens OX=9606 GN=H2AX PE=1 SV=2 9.79 2971.8 - 72459.5 - - - -0.2819 - 1.05 0.054 - 34.6 13 2 0 -0.0003 9 0 0 0 7.15E+06 6.00E+06 - - - -0.9167 1 221125_WJC_METTL3_EV_vs_WT_F09.16323.16323.3 9.13E-08 16/96 R.QSQIQVFEDGADTTSPETPDSSASK.V "sp|Q14203|DCTN1_HUMAN,tr|A0A804CDA6|A0A804CDA6_HUMAN,tr|E7EX90|E7EX90_HUMAN,tr|C9JJD0|C9JJD0_HUMAN,tr|A0A7P0Z4C3|A0A7P0Z4C3_HUMAN,tr|Q6AWB1|Q6AWB1_HUMAN,tr|E9PCY0|E9PCY0_HUMAN,tr|C9JKG6|C9JKG6_HUMAN" 8 2624.1726 2.06 133947 16323 3 2624.17458 875.7315 Dynactin subunit 1 OS=Homo sapiens OX=9606 GN=DCTN1 PE=1 SV=3 3.77 2974.4 - 157048 - - - 0.7679 - 2.67 0.621 - 235.6 1 2 0 0.002 25 0 0 0 3.20E+07 1.56E+07 - - - 7.7224 0.973 221125_WJC_METTL3_EV_vs_WT_F09.16331.16331.3 0.204 Apr-56 R.STSHK[136.11]PDEIYGMIER[166.11].L sp|Q86U44|MTA70_HUMAN 1 1779.8581 0.7 133953 16331 3 1779.859949 594.2933 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 5.42 2975.6 - 54774.4 - - - 1.0647 - 0.868 0.28 - 14.9 1 2 0 0.0019 15 0 0 0 1.73E+06 2.46E+06 - - - 1.2918 0.9783 221125_WJC_METTL3_EV_vs_WT_F09.16338.16338.3 0.00239 5/112 R.GGASQR[166.11]PLTPNQNQQGQQTDPLVAAAAVN.S "sp|Q14671|PUM1_HUMAN,tr|Q5T1Z8|Q5T1Z8_HUMAN,tr|H0YDK8|H0YDK8_HUMAN,tr|H0YEH2|H0YEH2_HUMAN,tr|Q5T1Z4|Q5T1Z4_HUMAN,tr|H0YED4|H0YED4_HUMAN,tr|E9PR38|E9PR38_HUMAN" 7 2940.4677 2.92 133958 16338 3 2940.471358 981.1632 Pumilio homolog 1 OS=Homo sapiens OX=9606 GN=PUM1 PE=1 SV=3 5.84 2976.6 - 58849.5 - - - 1.2338 - 1.083 0.537 - 13.2 1 1 0 0.0036 29 0 0 0 6.87E+06 2.36E+06 - - - 4.7094 1 221125_WJC_METTL3_EV_vs_WT_F09.16347.16347.3 2.11E-08 18/96 R.QSQIQVFEDGADTTSPETPDSSASK[136.11].V "sp|Q14203|DCTN1_HUMAN,tr|A0A804CDA6|A0A804CDA6_HUMAN,tr|E7EX90|E7EX90_HUMAN,tr|C9JJD0|C9JJD0_HUMAN,tr|A0A7P0Z4C3|A0A7P0Z4C3_HUMAN,tr|Q6AWB1|Q6AWB1_HUMAN,tr|E9PCY0|E9PCY0_HUMAN,tr|C9JKG6|C9JKG6_HUMAN" 8 2632.1868 2.05 133963 16347 3 2632.191509 878.4029 Dynactin subunit 1 OS=Homo sapiens OX=9606 GN=DCTN1 PE=1 SV=3 3.77 2977.9 - 374520 - - - 1.8023 - 2.896 0.642 - 294.9 1 2 0 0.0047 25 0 0 0 3.20E+07 1.56E+07 - - - 8.1427 0.9789 221125_WJC_METTL3_EV_vs_WT_F09.16348.16348.2 12 16-Jul R.AGLQFPVGR[166.11].V "sp|P16104|H2AX_HUMAN,sp|Q9BTM1|H2AJ_HUMAN,sp|Q93077|H2A1C_HUMAN,sp|Q99878|H2A1J_HUMAN,sp|Q16777|H2A2C_HUMAN,sp|Q8IUE6|H2A2B_HUMAN,sp|Q96QV6|H2A1A_HUMAN,sp|P0C0S5|H2AZ_HUMAN,sp|P04908|H2A1B_HUMAN,sp|P20671|H2A1D_HUMAN,sp|P0C0S8|H2A1_HUMAN,sp|Q6FI13|H2A2A_HUMAN,sp|Q96KK5|H2A1H_HUMAN,sp|Q71UI9|H2AV_HUMAN,sp|Q7L7L0|H2A3_HUMAN,tr|A0A0U1RR32|A0A0U1RR32_HUMAN,tr|A0A0U1RRH7|A0A0U1RRH7_HUMAN,tr|A0A3B3IS11|A0A3B3IS11_HUMAN,tr|C9J0D1|C9J0D1_HUMAN,tr|A0A494C189|A0A494C189_HUMAN" 20 953.5322 1.18 133964 16348 2 953.532951 477.7734 Histone H2AX OS=Homo sapiens OX=9606 GN=H2AX PE=1 SV=2 9.79 2978 - 158606 - - - 0.7666 - 1.119 0.118 - 178.7 1 2 0 0.0007 9 0 0 0 7.17E+06 6.07E+06 - - - 0.2376 0.9999 221125_WJC_METTL3_EV_vs_WT_F09.16359.16359.3 1.42E-08 23/112 K.QKGDTPASATAGDTLSVPAPAVQPEESLK.T "tr|A0A087WYS0|A0A087WYS0_HUMAN,tr|C9J406|C9J406_HUMAN,tr|H7C463|H7C463_HUMAN" 3 2864.4403 1.62 133972 16359 3 2864.444807 955.8207 MICOS complex subunit MIC60 OS=Homo sapiens OX=9606 GN=IMMT PE=1 SV=1 4.32 2979.5 - 522191 - - - 1.557 - 3.272 0.631 - 240.4 1 2 1 0.0045 29 0 0 0 3.18E+07 1.97E+07 - - - 8.301 0.894 221125_WJC_METTL3_EV_vs_WT_F09.16363.16363.3 2.96E-05 6/108 R.GGPPGQFHDNANGGQNGTVQEIMIPAGK.A "sp|Q92945|FUBP2_HUMAN,tr|M0R0I5|M0R0I5_HUMAN,tr|M0QYH3|M0QYH3_HUMAN,tr|M0R0C6|M0R0C6_HUMAN,tr|M0QXW7|M0QXW7_HUMAN,tr|A0A087WTP3|A0A087WTP3_HUMAN" 6 2790.3144 -1 133974 16363 3 2791.299531 931.1121 Far upstream element-binding protein 2 OS=Homo sapiens OX=9606 GN=KHSRP PE=1 SV=4 5.32 2980 - 93963 - - - 353.0627 - 1.495 0.549 - 17.5 1 2 0 0.9852 28 0 0 0 0.00E+00 0.00E+00 - - - 5.3131 0.9998 221125_WJC_METTL3_EV_vs_WT_F09.16364.16364.2 1.93E-05 Jul-48 R.QSQIQVFEDGADTTSPETPDSSASK.V "sp|Q14203|DCTN1_HUMAN,tr|A0A804CDA6|A0A804CDA6_HUMAN,tr|E7EX90|E7EX90_HUMAN,tr|C9JJD0|C9JJD0_HUMAN,tr|A0A7P0Z4C3|A0A7P0Z4C3_HUMAN,tr|Q6AWB1|Q6AWB1_HUMAN,tr|E9PCY0|E9PCY0_HUMAN,tr|C9JKG6|C9JKG6_HUMAN" 8 2624.1726 5.17 133975 16364 2 2624.170343 1313.0936 Dynactin subunit 1 OS=Homo sapiens OX=9606 GN=DCTN1 PE=1 SV=3 3.77 2980.1 - 40214.8 - - - -0.8467 - 1.581 0.543 - 77 1 2 0 -0.0022 25 0 0 0 1.23E+06 2.38E+05 - - - 4.1771 0.9999 221125_WJC_METTL3_EV_vs_WT_F09.16365.16365.3 7.53E-06 Aug-52 K.K[136.11]GPGEVAGTVTGQK[136.11].R "sp|Q86U44|MTA70_HUMAN,tr|F5H6D8|F5H6D8_HUMAN,tr|H0YFV6|H0YFV6_HUMAN,tr|B4DTN4|B4DTN4_HUMAN" 4 1343.738 0.01 133976 16365 3 1343.738508 448.9199 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 8.59 2980.2 - 80238.8 - - - 0.3937 - 1.827 0.501 - 107.2 1 2 0 0.0005 14 0 0 0 2.95E+04 4.90E+06 - - - 5.7271 0.9989 221125_WJC_METTL3_EV_vs_WT_F09.16379.16379.3 4.81E-09 15/100 R.LQQLLPASQSTQLPC[160.03]SSSPQETTQSR.P "sp|Q6W2J9|BCOR_HUMAN,tr|H7BZ37|H7BZ37_HUMAN,tr|H7C2V9|H7C2V9_HUMAN,tr|H7C231|H7C231_HUMAN" 4 2871.4032 3.46 133984 16379 3 2871.404169 958.1417 BCL-6 corepressor OS=Homo sapiens OX=9606 GN=BCOR PE=1 SV=1 5.99 2982.2 - 154318 - - - 0.3201 - 3.154 0.627 - 157.5 1 1 0 0.0009 26 0 0 0 4.78E+06 1.38E+06 - - - 8.1729 0.9971 221125_WJC_METTL3_EV_vs_WT_F09.16380.16380.4 0.386 11/156 R.LNEQEGVPSVFNPPPSR[166.11]PLQVNTADHR[166.11].L sp|Q96CS3|FAF2_HUMAN 1 3017.5222 1.12 133985 16380 4 3017.523415 755.3878 FAS-associated factor 2 OS=Homo sapiens OX=9606 GN=FAF2 PE=1 SV=2 5.45 2982.3 - 95068.9 - - - 0.3954 - 1.892 0.252 - 51.3 1 2 0 0.0012 27 0 0 0 2.12E+07 1.89E+07 - - - 1.6186 0.9998 221125_WJC_METTL3_EV_vs_WT_F09.16385.16385.4 0.00165 13/156 R.LNEQEGVPSVFNPPPSRPLQVNTADHR.L sp|Q96CS3|FAF2_HUMAN 1 2997.5057 1.12 133987 16385 4 2997.510226 750.3837 FAS-associated factor 2 OS=Homo sapiens OX=9606 GN=FAF2 PE=1 SV=2 5.45 2983 - 164931 - - - 1.5159 - 2.033 0.4 - 67.4 1 2 0 0.0045 27 0 0 0 2.12E+07 1.89E+07 - - - 2.9283 0.9841 221125_WJC_METTL3_EV_vs_WT_F09.16387.16387.4 0.00458 7/102 K.RPLDDGVGNQLGALVHQR.T sp|Q96I24|FUBP3_HUMAN 1 1944.029 2.03 133989 16387 4 1944.040262 487.0145 Far upstream element-binding protein 3 OS=Homo sapiens OX=9606 GN=FUBP3 PE=1 SV=2 6.75 2983.3 - 62343.1 - - - 5.8158 - 1.425 0.33 - 25.8 1 2 0 0.0113 18 0 0 0 1.65E+07 8.14E+06 - - - 2.2165 0.9997 221125_WJC_METTL3_EV_vs_WT_F09.16392.16392.4 0.00186 8/168 K.IQIASESSGIPER[166.11]PC[160.03]VLTGTPESIEQAK[136.11]R[166.11].L sp|Q96I24|FUBP3_HUMAN 1 3180.6443 2.11 133991 16392 4 3180.646426 796.1684 Far upstream element-binding protein 3 OS=Homo sapiens OX=9606 GN=FUBP3 PE=1 SV=2 4.95 2984.1 - 106726 - - - 0.6631 - 1.588 0.379 - 28.6 1 2 0 0.0021 29 0 0 0 5.50E+06 2.61E+06 - - - 2.6668 0.9999 221125_WJC_METTL3_EV_vs_WT_F09.16394.16394.3 1.13E-05 Sep-68 K.R[166.11]PLDDGVGNQLGALVHQR[166.11].T sp|Q96I24|FUBP3_HUMAN 1 1964.0455 2.11 133993 16394 3 1964.050173 655.6891 Far upstream element-binding protein 3 OS=Homo sapiens OX=9606 GN=FUBP3 PE=1 SV=2 6.75 2984.3 - 43971.2 - - - 2.3813 - 2.252 0.54 - 83.6 1 2 0 0.0047 18 0 0 0 1.35E+07 6.43E+06 - - - 6.5807 0.9989 221125_WJC_METTL3_EV_vs_WT_F09.16398.16398.3 3.50E-08 16/100 R.LQQLLPASQSTQLPC[160.03]SSSPQETTQSR[166.11].P "sp|Q6W2J9|BCOR_HUMAN,tr|H7BZ37|H7BZ37_HUMAN,tr|H7C2V9|H7C2V9_HUMAN,tr|H7C231|H7C231_HUMAN" 4 2881.4115 3.52 133995 16398 3 2881.408751 961.4778 BCL-6 corepressor OS=Homo sapiens OX=9606 GN=BCOR PE=1 SV=1 5.99 2984.9 - 110460 - - - -0.961 - 3.168 0.628 - 202.8 1 1 0 -0.0028 26 0 0 0 4.78E+06 1.36E+06 - - - 8.1937 0.9999 221125_WJC_METTL3_EV_vs_WT_F09.16402.16402.4 0.000229 12/168 K.IQIASESSGIPERPC[160.03]VLTGTPESIEQAKR.L sp|Q96I24|FUBP3_HUMAN 1 3152.6136 2.11 133997 16402 4 3152.617705 789.1607 Far upstream element-binding protein 3 OS=Homo sapiens OX=9606 GN=FUBP3 PE=1 SV=2 4.95 2985.6 - 289558 - - - 1.3094 - 2.07 0.443 - 49.3 1 2 0 0.0041 29 0 0 0 5.52E+06 2.61E+06 - - - 3.305 0.9999 221125_WJC_METTL3_EV_vs_WT_F09.16403.16403.2 9.56E-07 28-Oct K.NQVALNPQNTVFDAK[136.11].R "sp|P0DMV8|HS71A_HUMAN,sp|P0DMV9|HS71B_HUMAN,tr|A0A0G2JIW1|A0A0G2JIW1_HUMAN" 3 1665.8566 0.09 133998 16403 2 1665.85463 833.9356 Heat shock 70 kDa protein 1A OS=Homo sapiens OX=9606 GN=HSPA1A PE=1 SV=1 5.84 2985.8 - 77080.6 - - - -1.173 - 2.038 0.606 - 247.7 1 2 0 -0.002 15 0 0 0 8.14E+05 9.56E+06 - - - 5.2667 0.9999 221125_WJC_METTL3_EV_vs_WT_F09.16404.16404.3 2.07E-05 Aug-52 R.SDSFENPVLQQHFR[166.11].N "sp|P12956|XRCC6_HUMAN,tr|B1AHC9|B1AHC9_HUMAN" 2 1712.8146 0.37 133999 16404 3 1712.816512 571.9455 X-ray repair cross-complementing protein 6 OS=Homo sapiens OX=9606 GN=XRCC6 PE=1 SV=2 5.3 2985.9 - 62770 - - - 1.1145 - 1.683 0.485 - 80.6 1 2 0 0.0019 14 0 0 0 8.98E+05 2.46E+06 - - - 5.3302 1 221125_WJC_METTL3_EV_vs_WT_F09.16410.16410.4 4.00E-06 19/102 K.R[166.11]PLDDGVGNQLGALVHQR[166.11].T sp|Q96I24|FUBP3_HUMAN 1 1964.0455 2.03 134002 16410 4 1964.047312 492.0187 Far upstream element-binding protein 3 OS=Homo sapiens OX=9606 GN=FUBP3 PE=1 SV=2 6.75 2986.7 - 256424 - - - 0.9246 - 3.445 0.496 - 310.1 1 2 0 0.0018 18 0 0 0 1.65E+07 8.14E+06 - - - 3.9664 0.9997 221125_WJC_METTL3_EV_vs_WT_F09.16432.16432.3 0.000127 Nov-68 R.VAPEEHPVLLTEAPLNPK.A "sp|P63261|ACTG_HUMAN,sp|P60709|ACTB_HUMAN,tr|A0A804GS07|A0A804GS07_HUMAN,tr|I3L3I0|I3L3I0_HUMAN,tr|G5E9R0|G5E9R0_HUMAN,tr|E7EVS6|E7EVS6_HUMAN,tr|A0A6Q8PFE4|A0A6Q8PFE4_HUMAN,tr|J3KT65|J3KT65_HUMAN,tr|I3L3R2|I3L3R2_HUMAN,tr|K7EM38|K7EM38_HUMAN,tr|A0A6Q8PH58|A0A6Q8PH58_HUMAN,tr|I3L1U9|I3L1U9_HUMAN,tr|A0A2R8Y793|A0A2R8Y793_HUMAN,tr|I3L4N8|I3L4N8_HUMAN,tr|A0A2R8YGF8|A0A2R8YGF8_HUMAN" 15 1953.0571 2.47 134015 16432 3 1953.061896 652.0263 "Actin, cytoplasmic 2 OS=Homo sapiens OX=9606 GN=ACTG1 PE=1 SV=1" 4.75 2989.8 - 207877 - - - 2.4413 - 2.249 0.394 - 160.2 1 2 0 0.0048 18 0 0 0 1.12E+07 4.54E+06 - - - 4.9496 0.9876 221125_WJC_METTL3_EV_vs_WT_F09.16435.16435.3 0.327 Apr-52 R.SDSFENPVLQQHFR.N "sp|P12956|XRCC6_HUMAN,tr|B1AHC9|B1AHC9_HUMAN" 2 1702.8063 0.37 134016 16435 3 1702.808075 568.6094 X-ray repair cross-complementing protein 6 OS=Homo sapiens OX=9606 GN=XRCC6 PE=1 SV=2 5.3 2990.2 - 31101.8 - - - 1.023 - 0.932 0.304 - 14.7 1 2 0 0.0017 14 0 0 0 8.98E+05 2.45E+06 - - - 1.7417 1 221125_WJC_METTL3_EV_vs_WT_F09.16443.16443.3 1.35E-07 24/68 K.RPLDDGVGNQLGALVHQR.T sp|Q96I24|FUBP3_HUMAN 1 1944.029 2.11 134021 16443 3 1944.031419 649.0169 Far upstream element-binding protein 3 OS=Homo sapiens OX=9606 GN=FUBP3 PE=1 SV=2 6.75 2991.4 - 272917 - - - 1.267 - 4.188 0.584 - 706.3 1 2 0 0.0025 18 0 0 0 1.36E+07 6.46E+06 - - - 8.6167 1 221125_WJC_METTL3_EV_vs_WT_F09.16469.16469.3 5.11E-14 18/84 K.DHTPSQELALTQSVGGDSSADR[166.11].L "sp|Q86U44|MTA70_HUMAN,tr|H0YFV6|H0YFV6_HUMAN" 2 2280.0494 0.02 134033 16469 3 2280.049132 761.0237 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 4.22 2995 - 159429 - - - -0.1031 - 4.032 0.691 - 315.8 1 2 0 -0.0002 22 0 0 0 2.63E+05 1.60E+07 - - - 9.5495 0.9838 221125_WJC_METTL3_EV_vs_WT_F09.16475.16475.4 0.382 6/150 K.KPLPDHVSIVEPKDEILPTTPISEQK.G "sp|P23396|RS3_HUMAN,tr|H0YEU2|H0YEU2_HUMAN,tr|E9PSF4|E9PSF4_HUMAN,tr|E9PL09|E9PL09_HUMAN,tr|E9PPU1|E9PPU1_HUMAN" 5 2909.575 0.77 134036 16475 4 2909.578932 728.401 40S ribosomal protein S3 OS=Homo sapiens OX=9606 GN=RPS3 PE=1 SV=2 4.9 2995.7 - 51968.5 - - - 1.3548 - 1.403 0.251 - 11.6 1 2 1 0.0039 26 0 0 0 1.24E+07 1.62E+07 - - - 1.5164 0.998 221125_WJC_METTL3_EV_vs_WT_F09.16479.16479.4 0.0187 8/150 K.K[136.11]PLPDHVSIVEPK[136.11]DEILPTTPISEQK[136.11].G "sp|P23396|RS3_HUMAN,tr|H0YEU2|H0YEU2_HUMAN,tr|E9PSF4|E9PSF4_HUMAN,tr|E9PL09|E9PL09_HUMAN,tr|E9PPU1|E9PPU1_HUMAN" 5 2933.6176 0.77 134038 16479 4 2933.621632 734.4117 40S ribosomal protein S3 OS=Homo sapiens OX=9606 GN=RPS3 PE=1 SV=2 4.9 2996.2 - 81223.8 - - - 1.3778 - 1.555 0.349 - 26.5 1 2 1 0.004 26 0 0 0 1.26E+07 1.64E+07 - - - 2.4018 0.9999 221125_WJC_METTL3_EV_vs_WT_F09.16506.16506.3 1.13E-07 7/116 R.GGAVGGEKDPPPPGTQGVVYFADDDNTYSR.E "sp|O94766|B3GA3_HUMAN,tr|G3V150|G3V150_HUMAN" 2 3065.4003 1.76 134051 16506 3 3065.398164 1022.8074 Galactosylgalactosylxylosylprotein 3-beta-glucuronosyltransferase 3 OS=Homo sapiens OX=9606 GN=B3GAT3 PE=1 SV=2 4.04 2999.9 - 57681 - - - -0.688 - 2.037 0.642 - 28.7 1 2 1 -0.0021 30 0 0 0 4.61E+06 2.61E+06 - - - 7.3339 0.9513 221125_WJC_METTL3_EV_vs_WT_F09.16553.16553.4 63.2 1/174 K.GSAC[160.03]EFC[160.03]MC[160.03]DHGQVTC[160.03]QTGEC[160.03]AKVEC[160.03]ARDE.E "sp|Q86XX4|FRAS1_HUMAN,tr|A0A804HI32|A0A804HI32_HUMAN,tr|H0Y9A6|H0Y9A6_HUMAN,tr|H0Y9C9|H0Y9C9_HUMAN,tr|A0A804HL50|A0A804HL50_HUMAN" 5 3551.3397 161.91 134076 16553 4 3551.337516 888.8422 Extracellular matrix organizing protein FRAS1 OS=Homo sapiens OX=9606 GN=FRAS1 PE=1 SV=2 4.5 3006.4 - 63413.1 - - - -0.615 - 0.242 0.501 - 0.3 1 1 2 -0.0022 30 0 0 0 7.53E+07 4.65E+05 - - - 3.1519 0.9972 221125_WJC_METTL3_EV_vs_WT_F09.16581.16581.3 0.0208 Jun-52 K.K[136.11]GPGEVAGTVTGQK[136.11].R "sp|Q86U44|MTA70_HUMAN,tr|F5H6D8|F5H6D8_HUMAN,tr|H0YFV6|H0YFV6_HUMAN,tr|B4DTN4|B4DTN4_HUMAN" 4 1343.738 0 134090 16581 3 1343.738099 448.9199 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 8.59 3010.5 - 100527 - - - 0.0893 - 1.223 0.317 - 44.9 1 2 0 0.0001 14 0 0 0 1.36E+04 5.34E+06 - - - 2.6092 0.9999 221125_WJC_METTL3_EV_vs_WT_F09.16599.16599.4 9.04E-05 9/120 K.KSESEVEEAAAIIAQRPDNPR.E "sp|Q16643|DREB_HUMAN,tr|D6R9Q9|D6R9Q9_HUMAN,tr|D6R9W4|D6R9W4_HUMAN" 3 2309.1612 1.18 134101 16599 4 2309.165064 578.2976 Drebrin OS=Homo sapiens OX=9606 GN=DBN1 PE=1 SV=4 4.59 3013 - 85555.6 - - - 1.6941 - 2.124 0.482 - 70.5 1 2 0 0.0039 21 0 0 0 8.64E+06 7.30E+06 - - - 3.6693 0.9998 221125_WJC_METTL3_EV_vs_WT_F09.16604.16604.4 3.37E-05 9/120 K.K[136.11]SESEVEEAAAIIAQR[166.11]PDNPR[166.11].E "sp|Q16643|DREB_HUMAN,tr|D6R9Q9|D6R9Q9_HUMAN,tr|D6R9W4|D6R9W4_HUMAN" 3 2337.1919 1.2 134103 16604 4 2337.199358 585.3052 Drebrin OS=Homo sapiens OX=9606 GN=DBN1 PE=1 SV=4 4.59 3013.8 - 67179.7 - - - 3.1944 - 2.021 0.466 - 54.7 1 2 0 0.0075 21 0 0 0 8.64E+06 7.18E+06 - - - 3.5126 0.9996 221125_WJC_METTL3_EV_vs_WT_F09.16626.16626.3 0.000626 Jul-80 K.K[136.11]SESEVEEAAAIIAQR[166.11]PDNPR[166.11].E "sp|Q16643|DREB_HUMAN,tr|D6R9Q9|D6R9Q9_HUMAN,tr|D6R9W4|D6R9W4_HUMAN" 3 2337.1919 1.1 134110 16626 3 2337.194797 780.0712 Drebrin OS=Homo sapiens OX=9606 GN=DBN1 PE=1 SV=4 4.59 3017.4 - 45620.4 - - - 1.2429 - 1.601 0.399 - 33.2 1 2 0 0.0029 21 0 0 0 1.91E+06 1.73E+06 - - - 4.116 0.9962 221125_WJC_METTL3_EV_vs_WT_F09.16651.16651.3 0.00729 6/104 R.DEQAFPALSSSSVNQSASQSSNPC[160.03]VQR.K sp|Q01804|OTUD4_HUMAN 1 2880.2944 4.88 134124 16651 3 2880.301757 961.1054 OTU domain-containing protein 4 OS=Homo sapiens OX=9606 GN=OTUD4 PE=1 SV=4 4.37 3021.1 - 31629.9 - - - 2.5445 - 1.182 0.374 - 19.8 1 2 0 0.0073 27 0 0 0 1.27E+06 2.61E+05 - - - 3.0924 0.9236 221125_WJC_METTL3_EV_vs_WT_F09.16661.16661.2 0.82 28-Mar R.GALQNIIPASTGAAK.A "sp|P04406|G3P_HUMAN,tr|E7EUT5|E7EUT5_HUMAN" 2 1410.7831 1.31 134129 16661 2 1410.785222 706.3988 Glyceraldehyde-3-phosphate dehydrogenase OS=Homo sapiens OX=9606 GN=GAPDH PE=1 SV=3 8.75 3022.4 - 19363.4 - - - 1.5197 - 0.864 0.146 - 30.8 2 2 0 0.0021 15 0 0 0 7.61E+06 5.80E+06 - - - -0.3752 1 221125_WJC_METTL3_EV_vs_WT_F09.16681.16681.3 4.37E-12 17/84 K.DHTPSQELALTQSVGGDSSADR[166.11].L "sp|Q86U44|MTA70_HUMAN,tr|H0YFV6|H0YFV6_HUMAN" 2 2280.0494 0.06 134138 16681 3 2280.048192 761.0237 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 4.22 3025.5 - 160107 - - - -0.5153 - 3.945 0.703 - 250.4 1 2 0 -0.0012 22 0 0 0 8.25E+05 1.27E+07 - - - 9.6313 0.9998 221125_WJC_METTL3_EV_vs_WT_F09.16690.16690.4 0.0171 13/150 K.K[136.11]PLPDHVSIVEPK[136.11]DEILPTTPISEQK[136.11].G "sp|P23396|RS3_HUMAN,tr|H0YEU2|H0YEU2_HUMAN,tr|E9PSF4|E9PSF4_HUMAN,tr|E9PL09|E9PL09_HUMAN,tr|E9PPU1|E9PPU1_HUMAN" 5 2933.6176 0.77 134144 16690 4 2933.619451 734.4117 40S ribosomal protein S3 OS=Homo sapiens OX=9606 GN=RPS3 PE=1 SV=2 4.9 3026.6 - 162305 - - - 0.6344 - 2.923 0.457 - 67.4 1 2 1 0.0019 26 0 0 0 1.26E+07 1.64E+07 - - - 3.5416 0.9803 221125_WJC_METTL3_EV_vs_WT_F09.16695.16695.3 1.47 Jun-48 R.LVHPGVAEVVFVK[136.11].K "sp|Q9BY77|PDIP3_HUMAN,tr|F6VRR5|F6VRR5_HUMAN" 2 1400.8271 1.53 134148 16695 3 1400.828843 467.9497 Polymerase delta-interacting protein 3 OS=Homo sapiens OX=9606 GN=POLDIP3 PE=1 SV=2 6.75 3027.3 - 34151.9 - - - 1.2286 - 0.983 0.272 - 35.6 1 2 0 0.0017 13 0 0 0 1.45E+06 9.49E+05 - - - 1.5256 1 221125_WJC_METTL3_EV_vs_WT_F09.16701.16701.4 2.49E-06 18/150 K.KPLPDHVSIVEPKDEILPTTPISEQK.G "sp|P23396|RS3_HUMAN,tr|H0YEU2|H0YEU2_HUMAN,tr|E9PSF4|E9PSF4_HUMAN,tr|E9PL09|E9PL09_HUMAN,tr|E9PPU1|E9PPU1_HUMAN" 5 2909.575 0.77 134151 16701 4 2909.579759 728.401 40S ribosomal protein S3 OS=Homo sapiens OX=9606 GN=RPS3 PE=1 SV=2 4.9 3028.1 - 113419 - - - 1.6391 - 3.883 0.649 - 189.3 1 2 1 0.0048 26 0 0 0 1.24E+07 1.62E+07 - - - 5.3015 0.9998 221125_WJC_METTL3_EV_vs_WT_F09.16705.16705.3 1.96E-06 7/100 K.ISEEQQQLQQALAPAQASSNSSTPTR.M "sp|Q13439|GOGA4_HUMAN,tr|Q86W71|Q86W71_HUMAN,tr|C9J0Y3|C9J0Y3_HUMAN,tr|E7EVX2|E7EVX2_HUMAN,tr|C9JHJ5|C9JHJ5_HUMAN" 5 2769.3529 364.34 134153 16705 3 2769.360717 924.1249 Golgin subfamily A member 4 OS=Homo sapiens OX=9606 GN=GOLGA4 PE=1 SV=1 4.53 3028.7 - 50499.7 - - - 2.8122 - 1.591 0.565 - 24.6 1 2 0 0.0078 26 0 0 0 6.49E+07 1.78E+05 - - - 5.9054 0.9872 221125_WJC_METTL3_EV_vs_WT_F09.16724.16724.2 0.19 28-Mar R.FVIGGPQGDAGLTGR.K sp|P31153|METK2_HUMAN 1 1443.747 999 134164 16724 2 1443.745253 722.8808 S-adenosylmethionine synthase isoform type-2 OS=Homo sapiens OX=9606 GN=MAT2A PE=1 SV=1 5.84 3031.4 - 34095.9 - - - -1.2287 - 0.841 0.304 - 20.9 3 2 0 -0.0018 15 0 0 0 8.08E+05 0.00E+00 - - - 0.6469 0.9918 221125_WJC_METTL3_EV_vs_WT_F09.16731.16731.4 1.22E-09 19/150 T.VAAFASSLVSGLNSSASEPAK[136.11]EPAK[136.11]K[136.11].S "sp|Q86U44|MTA70_HUMAN,tr|F5H6D8|F5H6D8_HUMAN,tr|H0YFV6|H0YFV6_HUMAN,tr|B4DTN4|B4DTN4_HUMAN" 4 2569.3814 0.01 134167 16731 4 2569.376696 643.3526 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 8.47 3032.4 - 363088 - - - -1.8238 - 3.599 0.613 - 209.2 1 1 1 -0.0047 26 0 0 0 9.43E+04 1.21E+07 - - - 4.9642 0.8728 221125_WJC_METTL3_EV_vs_WT_F09.16744.16744.4 0.754 4/114 R.YNEC[160.03]LMNFSC[160.03]NGKNGSSEGR[166.11].L "sp|Q96LI5|CNO6L_HUMAN,tr|H0Y9Z5|H0Y9Z5_HUMAN" 2 2332.9499 - 134174 16744 4 2332.945664 584.2447 CCR4-NOT transcription complex subunit 6-like OS=Homo sapiens OX=9606 GN=CNOT6L PE=1 SV=2 6.13 3034.1 - 224221 - - - -1.8029 - 0.97 0.184 - 12.6 1 2 1 -0.0042 20 0 0 0 - - - - - 0.8162 0.9974 221125_WJC_METTL3_EV_vs_WT_F09.16746.16746.4 0.00535 5/156 K.RVGAGDTSDWPTVLSESSTTVAGKPEK.G sp|Q9BUA3|SPNDC_HUMAN 1 2774.3723 7.64 134175 16746 4 2774.366334 694.6003 Spindlin interactor and repressor of chromatin-binding protein OS=Homo sapiens OX=9606 GN=SPINDOC PE=1 SV=3 4.78 3034.3 - 102997 - - - -2.1385 - 1.366 0.292 - 10.1 1 2 0 -0.0059 27 0 0 0 7.25E+06 9.49E+05 - - - 1.8635 0.9893 221125_WJC_METTL3_EV_vs_WT_F09.16752.16752.2 0.0104 18-Aug K.WTLLQEQGTK.T "sp|P48668|K2C6C_HUMAN,sp|P04259|K2C6B_HUMAN,sp|P13647|K2C5_HUMAN,sp|P02538|K2C6A_HUMAN,tr|F8W0C6|F8W0C6_HUMAN" 5 1202.6295 549.08 134179 16752 2 1202.622537 602.322 "Keratin, type II cytoskeletal 6C OS=Homo sapiens OX=9606 GN=KRT6C PE=1 SV=3" 6 3035 - 207061 - - - -5.8214 - 1.68 0.411 - 228.2 1 2 0 -0.007 10 0 0 0 5.87E+06 1.07E+04 - - - 3.5226 1 221125_WJC_METTL3_EV_vs_WT_F09.16758.16758.4 2.95E-07 11/144 R.SLNNFC[160.03]SQIGDDRPISYC[160.03]HFSPNSK.M sp|O43172|PRP4_HUMAN 1 2942.3076 5.99 134181 16758 4 2942.300149 736.5842 U4\U6 small nuclear ribonucleoprotein Prp4 OS=Homo sapiens OX=9606 GN=PRPF4 PE=1 SV=2 6.46 3035.8 - 246445 - - - -2.5242 - 2.193 0.599 - 61.7 1 2 0 -0.0074 25 0 0 0 4.45E+06 7.43E+05 - - - 4.6874 1 221125_WJC_METTL3_EV_vs_WT_F09.16783.16783.3 1.28E-08 15/96 R.TR[166.11]EDNDLDSQVSQEGLGPVLQPQPK[136.11].S "sp|O00165|HAX1_HUMAN,tr|E9PIQ7|E9PIQ7_HUMAN" 2 2767.3743 2.37 134193 16783 3 2767.357348 923.4654 HCLS1-associated protein X-1 OS=Homo sapiens OX=9606 GN=HAX1 PE=1 SV=2 4.1 3039.1 - 376732 - - - -6.1387 - 2.937 0.675 - 203.3 1 2 1 -0.017 25 0 0 0 1.40E+08 5.88E+07 - - - 8.5396 1 221125_WJC_METTL3_EV_vs_WT_F09.16788.16788.3 1.15E-21 25/96 R.TREDNDLDSQVSQEGLGPVLQPQPK.S "sp|O00165|HAX1_HUMAN,tr|E9PIQ7|E9PIQ7_HUMAN" 2 2749.3519 2.38 134195 16788 3 2749.340961 917.4579 HCLS1-associated protein X-1 OS=Homo sapiens OX=9606 GN=HAX1 PE=1 SV=2 4.1 3039.7 - 768923 - - - -3.9664 - 4.583 0.742 - 553.6 1 2 1 -0.0109 25 0 0 0 1.40E+08 5.88E+07 - - - 10.3119 0.9979 221125_WJC_METTL3_EV_vs_WT_F09.16830.16830.4 5.16E-07 14/132 K.VK[136.11]ADR[166.11]DESSPYAAMLAAQDVAQR[166.11].C "sp|P62263|RS14_HUMAN,tr|A0A2R8Y811|A0A2R8Y811_HUMAN,tr|E5RH77|E5RH77_HUMAN" 3 2519.2433 1.23 134204 16830 4 2519.232575 630.8181 40S ribosomal protein S14 OS=Homo sapiens OX=9606 GN=RPS14 PE=1 SV=3 4.68 3046 - 477407 - - - -4.2477 - 2.717 0.444 - 153.2 1 2 2 -0.0107 23 0 0 0 4.47E+07 3.63E+07 - - - 3.4114 0.9998 221125_WJC_METTL3_EV_vs_WT_F09.16834.16834.4 1.73E-09 18/132 K.VKADRDESSPYAAMLAAQDVAQR.C "sp|P62263|RS14_HUMAN,tr|A0A2R8Y811|A0A2R8Y811_HUMAN,tr|E5RH77|E5RH77_HUMAN" 3 2491.2125 1.23 134205 16834 4 2491.20578 623.8104 40S ribosomal protein S14 OS=Homo sapiens OX=9606 GN=RPS14 PE=1 SV=3 4.68 3046.6 - 921996 - - - -2.7119 - 2.726 0.553 - 228.4 1 2 2 -0.0068 23 0 0 0 4.47E+07 3.63E+07 - - - 4.3623 0.9941 221125_WJC_METTL3_EV_vs_WT_F09.16869.16869.3 0.000743 Jun-52 K.K[136.11]GPGEVAGTVTGQK[136.11].R "sp|Q86U44|MTA70_HUMAN,tr|F5H6D8|F5H6D8_HUMAN,tr|H0YFV6|H0YFV6_HUMAN,tr|B4DTN4|B4DTN4_HUMAN" 4 1343.738 0.001 134221 16869 3 1343.729952 448.9199 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 8.59 3051.3 - 104469 - - - -5.9736 - 1.583 0.437 - 57.6 1 2 0 -0.008 14 0 0 0 0.00E+00 4.94E+06 - - - 4.6306 0.9994 221125_WJC_METTL3_EV_vs_WT_F09.16878.16878.2 0.00545 20-Jul K.DAVEDLESVGK.G sp|P81605|DCD_HUMAN 1 1160.5561 7.26 134225 16878 2 1160.553595 581.2853 Dermcidin OS=Homo sapiens OX=9606 GN=DCD PE=1 SV=2 3.92 3052.4 - 87467.7 - - - -2.1567 - 1.714 0.443 - 180.2 1 2 0 -0.0025 11 0 0 0 3.03E+06 4.18E+05 - - - 3.7699 0.9999 221125_WJC_METTL3_EV_vs_WT_F09.16903.16903.3 1.62E-11 18/84 K.TKEQVTNVGGAVVTGVTAVAQK.T "sp|P37840|SYUA_HUMAN,tr|A0A669KB41|A0A669KB41_HUMAN,tr|A0A669KBH5|A0A669KBH5_HUMAN,tr|H6UYS7|H6UYS7_HUMAN,tr|E7EPV7|E7EPV7_HUMAN" 5 2156.1801 1.67 134235 16903 3 2156.176988 719.734 Alpha-synuclein OS=Homo sapiens OX=9606 GN=SNCA PE=1 SV=1 8.26 3055.8 - 291311 - - - -1.4419 - 3.634 0.609 - 368.7 1 2 1 -0.0031 22 0 0 0 1.03E+08 6.15E+07 - - - 8.3881 0.9999 221125_WJC_METTL3_EV_vs_WT_F09.16904.16904.3 0.000368 Jul-52 K.HWPFMVVNDAGR[166.11]PK[136.11].V "sp|P11142|HSP7C_HUMAN,tr|E9PQQ4|E9PQQ4_HUMAN,tr|E9PNE6|E9PNE6_HUMAN,tr|E9PKE3|E9PKE3_HUMAN,tr|E9PN89|E9PN89_HUMAN,tr|E9PLF4|E9PLF4_HUMAN,tr|E9PK54|E9PK54_HUMAN,tr|E9PN25|E9PN25_HUMAN,tr|E9PPY6|E9PPY6_HUMAN,tr|E9PQK7|E9PQK7_HUMAN" 10 1670.847 0.05 134236 16904 3 1670.84244 557.9563 Heat shock cognate 71 kDa protein OS=Homo sapiens OX=9606 GN=HSPA8 PE=1 SV=1 8.75 3055.9 - 62777.3 - - - -2.7507 - 1.797 0.53 - 63.8 1 2 0 -0.0046 14 0 0 0 1.05E+05 2.03E+06 - - - 6.0053 0.9999 221125_WJC_METTL3_EV_vs_WT_F09.16909.16909.3 2.84E-06 11/128 R.SDSPVPTAPTSGGPK[136.11]PSTASAVPELATDPELEK[136.11].K "sp|Q86U44|MTA70_HUMAN,tr|B4E349|B4E349_HUMAN,tr|F5H6D8|F5H6D8_HUMAN,tr|B4DTN4|B4DTN4_HUMAN" 4 3248.6271 0.01 134239 16909 3 3248.617418 1083.883 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 4.18 3056.6 - 194552 - - - -2.9797 - 2.122 0.572 - 58.1 1 2 0 -0.0097 33 0 0 0 8.80E+07 7.98E+09 - - - 6.6455 1 221125_WJC_METTL3_EV_vs_WT_F09.16926.16926.3 5.13E-08 23/84 K.TK[136.11]EQVTNVGGAVVTGVTAVAQK[136.11].T "sp|P37840|SYUA_HUMAN,tr|A0A669KB41|A0A669KB41_HUMAN,tr|A0A669KBH5|A0A669KBH5_HUMAN,tr|H6UYS7|H6UYS7_HUMAN,tr|E7EPV7|E7EPV7_HUMAN" 5 2172.2085 1.66 134246 16926 3 2172.203576 725.0768 Alpha-synuclein OS=Homo sapiens OX=9606 GN=SNCA PE=1 SV=1 8.26 3059 - 783405 - - - -2.2654 - 4.246 0.638 - 671 1 2 1 -0.0049 22 0 0 0 1.02E+08 6.15E+07 - - - 9.0799 0.9994 221125_WJC_METTL3_EV_vs_WT_F09.16932.16932.4 5.09E-06 14/126 K.TKEQVTNVGGAVVTGVTAVAQK.T "sp|P37840|SYUA_HUMAN,tr|A0A669KB41|A0A669KB41_HUMAN,tr|A0A669KBH5|A0A669KBH5_HUMAN,tr|H6UYS7|H6UYS7_HUMAN,tr|E7EPV7|E7EPV7_HUMAN" 5 2156.1801 2.04 134248 16932 4 2156.184472 540.0523 Alpha-synuclein OS=Homo sapiens OX=9606 GN=SNCA PE=1 SV=1 8.26 3059.8 - 312865 - - - 2.0291 - 2.365 0.423 - 138.4 1 2 1 0.0044 22 0 0 0 1.63E+07 7.98E+06 - - - 3.1882 0.9776 221125_WJC_METTL3_EV_vs_WT_F09.16953.16953.4 3.64E-05 13/192 R.SDSPVPTAPTSGGPK[136.11]PSTASAVPELATDPELEK[136.11].K "sp|Q86U44|MTA70_HUMAN,tr|B4E349|B4E349_HUMAN,tr|F5H6D8|F5H6D8_HUMAN,tr|B4DTN4|B4DTN4_HUMAN" 4 3248.6271 0.01 134258 16953 4 3249.619717 813.1641 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 4.18 3062.5 - 476641 - - - 305.5503 - 2.253 0.419 - 57.7 1 2 0 0.9926 33 0 0 0 3.19E+07 2.83E+09 - - - 2.8417 0.9931 221125_WJC_METTL3_EV_vs_WT_F09.16964.16964.3 1.32E-08 16/84 K.DHTPSQELALTQSVGGDSSADR[166.11].L "sp|Q86U44|MTA70_HUMAN,tr|H0YFV6|H0YFV6_HUMAN" 2 2280.0494 0 134264 16964 3 2281.040336 761.0237 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 4.22 3064 - 198961 - - - 434.6261 - 3.389 0.621 - 228.9 1 2 0 0.991 22 0 0 0 3.46E+04 9.72E+06 - - - 8.0827 0.9859 221125_WJC_METTL3_EV_vs_WT_F09.16968.16968.3 0.0323 Jun-48 K.LKDLFDYSPPLHK.N "sp|Q9NYF8|BCLF1_HUMAN,tr|E9PKI6|E9PKI6_HUMAN,tr|A0A1W2PQ43|A0A1W2PQ43_HUMAN,tr|E9PK91|E9PK91_HUMAN,tr|E9PK09|E9PK09_HUMAN,tr|E9PQN2|E9PQN2_HUMAN" 6 1571.8348 11.47 134265 16968 3 1571.833617 524.9522 Bcl-2-associated transcription factor 1 OS=Homo sapiens OX=9606 GN=BCLAF1 PE=1 SV=2 6.75 3064.5 - 126351 - - - -0.7399 - 1.315 0.292 - 48.6 1 2 1 -0.0012 13 0 0 0 3.35E+06 2.92E+05 - - - 2.5376 0.9995 221125_WJC_METTL3_EV_vs_WT_F09.16978.16978.3 4.07E-07 13/48 R.GYFEYIEENK[136.11]YSR[166.11].A "sp|Q00839|HNRPU_HUMAN,tr|Q5RI18|Q5RI18_HUMAN,tr|A0A1W2PP35|A0A1W2PP35_HUMAN,tr|A0A1W2PPS1|A0A1W2PPS1_HUMAN,tr|A0A1W2PRI6|A0A1W2PRI6_HUMAN" 5 1714.7958 1.05 134268 16978 3 1714.788808 572.6059 Heterogeneous nuclear ribonucleoprotein U OS=Homo sapiens OX=9606 GN=HNRNPU PE=1 SV=6 4.79 3066 - 135184 - - - -4.0611 - 2.607 0.599 - 215 1 2 1 -0.007 13 0 0 0 3.73E+06 3.55E+06 - - - 7.8143 1 221125_WJC_METTL3_EV_vs_WT_F09.17086.17086.2 6.37E-12 19/64 R.SDSPVPTAPTSGGPK[136.11]PSTASAVPELATDPELEK[136.11].K "sp|Q86U44|MTA70_HUMAN,tr|B4E349|B4E349_HUMAN,tr|F5H6D8|F5H6D8_HUMAN,tr|B4DTN4|B4DTN4_HUMAN" 4 3248.6271 0.001 134280 17086 2 3248.609336 1625.3208 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 4.18 3083.2 - 2.23E+06 - - - -5.4675 - 3.3 0.646 - 208.9 1 2 0 -0.0178 33 0 0 0 0.00E+00 4.45E+06 - - - 6.7421 1 221125_WJC_METTL3_EV_vs_WT_F09.17125.17125.4 3.98E-11 19/96 K.HSQAVEELAEQLEQTKR.V sp|P35579|MYH9_HUMAN 1 1995.0021 1.02 134287 17125 4 1994.996056 499.7578 Myosin-9 OS=Homo sapiens OX=9606 GN=MYH9 PE=1 SV=4 4.91 3089.2 - 301975 - - - -3.0456 - 3.677 0.624 - 400.5 1 2 0 -0.0061 17 0 0 0 1.06E+07 1.03E+07 - - - 5.1077 0.9983 221125_WJC_METTL3_EV_vs_WT_F09.17128.17128.4 0.0054 10/138 K.DTSSEEVNLSHIVPC[160.03]EPVPEEKPK.E sp|Q8N0X7|SPART_HUMAN 1 2719.3011 1.66 134288 17128 4 2719.290937 680.8325 Spartin OS=Homo sapiens OX=9606 GN=SPART PE=1 SV=1 4.41 3089.6 - 600106 - - - -3.7289 - 2.169 0.354 - 36.7 1 2 0 -0.0101 24 0 0 0 1.57E+07 9.49E+06 - - - 2.5529 1 221125_WJC_METTL3_EV_vs_WT_F09.17133.17133.3 0.00869 18/64 K.HSQAVEELAEQLEQTKR.V sp|P35579|MYH9_HUMAN 1 1995.0021 0.97 134291 17133 3 1995.000097 666.008 Myosin-9 OS=Homo sapiens OX=9606 GN=MYH9 PE=1 SV=4 4.91 3090.1 - 282818 - - - -1.02 - 4.181 0.585 - 566.5 1 2 0 -0.002 17 0 0 0 1.85E+07 1.90E+07 - - - 8.6756 0.9999 221125_WJC_METTL3_EV_vs_WT_F09.17134.17134.4 1.14E-06 17/96 K.HSQAVEELAEQLEQTK[136.11]R[166.11].V sp|P35579|MYH9_HUMAN 1 2013.0246 1.08 134292 17134 4 2013.016926 504.2634 Myosin-9 OS=Homo sapiens OX=9606 GN=MYH9 PE=1 SV=4 4.91 3090.3 - 267362 - - - -3.8132 - 3.257 0.584 - 236.7 1 2 0 -0.0077 17 0 0 0 1.12E+07 1.03E+07 - - - 4.717 0.9997 221125_WJC_METTL3_EV_vs_WT_F09.17142.17142.4 2.80E-06 13/138 K.DTSSEEVNLSHIVPC[160.03]EPVPEEK[136.11]PK[136.11].E sp|Q8N0X7|SPART_HUMAN 1 2735.3295 1.66 134295 17142 4 2735.316846 684.8396 Spartin OS=Homo sapiens OX=9606 GN=SPART PE=1 SV=1 4.41 3091.4 - 342107 - - - -4.6177 - 2.265 0.524 - 74.6 1 2 0 -0.0126 24 0 0 0 1.57E+07 9.49E+06 - - - 4.0458 0.9999 221125_WJC_METTL3_EV_vs_WT_F09.17144.17144.3 7.70E-05 9/112 K.GTTATSAQANSTPTSVASVVTSAESPASR.Q sp|Q86YP4|P66A_HUMAN 1 2735.321 2.21 134297 17144 3 2735.313421 912.7809 Transcriptional repressor p66-alpha OS=Homo sapiens OX=9606 GN=GATAD2A PE=1 SV=1 6 3091.7 - 268724 - - - -2.7562 - 2.193 0.535 - 72.6 1 2 0 -0.0075 29 0 0 0 2.83E+07 1.28E+07 - - - 6.3093 0.9998 221125_WJC_METTL3_EV_vs_WT_F09.17155.17155.3 4.80E-08 10/112 K.GTTATSAQANSTPTSVASVVTSAESPASR[166.11].Q sp|Q86YP4|P66A_HUMAN 1 2745.3292 2.21 134302 17155 3 2745.316145 916.117 Transcriptional repressor p66-alpha OS=Homo sapiens OX=9606 GN=GATAD2A PE=1 SV=1 6 3093.1 - 166704 - - - -4.7663 - 2.511 0.586 - 84.5 1 2 0 -0.0131 29 0 0 0 2.83E+07 1.28E+07 - - - 7.1878 0.9994 221125_WJC_METTL3_EV_vs_WT_F09.17156.17156.3 0.000605 Jul-52 K.K[136.11]GPGEVAGTVTGQK[136.11].R "sp|Q86U44|MTA70_HUMAN,tr|F5H6D8|F5H6D8_HUMAN,tr|H0YFV6|H0YFV6_HUMAN,tr|B4DTN4|B4DTN4_HUMAN" 4 1343.738 0.001 134303 17156 3 1343.73216 448.9199 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 8.59 3093.2 - 110699 - - - -4.3305 - 1.671 0.526 - 61.2 1 2 0 -0.0058 14 0 0 0 0.00E+00 3.67E+06 - - - 5.7672 0.9999 221125_WJC_METTL3_EV_vs_WT_F09.17161.17161.4 1.02E-06 15/120 R.DSFDDRGPSLNPVLDYDHGSR.S "sp|P43243|MATR3_HUMAN,tr|A8MXP9|A8MXP9_HUMAN,tr|D6R991|D6R991_HUMAN,tr|A0A0R4J2E8|A0A0R4J2E8_HUMAN,tr|D6REM6|D6REM6_HUMAN" 5 2361.0622 1.41 134306 17161 4 2361.060092 591.2728 Matrin-3 OS=Homo sapiens OX=9606 GN=MATR3 PE=1 SV=2 4.28 3093.9 - 305030 - - - -0.8784 - 2.979 0.549 - 144.8 1 2 1 -0.0021 21 0 0 0 1.32E+08 9.41E+07 - - - 4.3648 0.9999 221125_WJC_METTL3_EV_vs_WT_F09.17162.17162.4 4.09E-08 14/120 R.DSFDDR[166.11]GPSLNPVLDYDHGSR[166.11].S "sp|P43243|MATR3_HUMAN,tr|A8MXP9|A8MXP9_HUMAN,tr|D6R991|D6R991_HUMAN,tr|A0A0R4J2E8|A0A0R4J2E8_HUMAN,tr|D6REM6|D6REM6_HUMAN" 5 2381.0787 1.41 134307 17162 4 2381.0764 596.277 Matrin-3 OS=Homo sapiens OX=9606 GN=MATR3 PE=1 SV=2 4.28 3094 - 213174 - - - -0.9685 - 2.732 0.619 - 138.3 1 2 1 -0.0023 21 0 0 0 1.32E+08 9.41E+07 - - - 4.9454 1 221125_WJC_METTL3_EV_vs_WT_F09.17167.17167.3 6.52E-11 15/84 K.DHTPSQELALTQSVGGDSSADR[166.11].L "sp|Q86U44|MTA70_HUMAN,tr|H0YFV6|H0YFV6_HUMAN" 2 2280.0494 0.001 134309 17167 3 2280.043772 761.0237 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 4.22 3094.7 - 233696 - - - -2.4539 - 3.408 0.611 - 241.3 1 2 0 -0.0056 22 0 0 0 0.00E+00 1.60E+07 - - - 8.2574 0.9993 221125_WJC_METTL3_EV_vs_WT_F09.17168.17168.3 4.92E-06 Aug-80 R.DSFDDR[166.11]GPSLNPVLDYDHGSR[166.11].S "sp|P43243|MATR3_HUMAN,tr|A8MXP9|A8MXP9_HUMAN,tr|D6R991|D6R991_HUMAN,tr|A0A0R4J2E8|A0A0R4J2E8_HUMAN,tr|D6REM6|D6REM6_HUMAN" 5 2381.0787 1.36 134310 17168 3 2381.070939 794.7002 Matrin-3 OS=Homo sapiens OX=9606 GN=MATR3 PE=1 SV=2 4.28 3094.8 - 95217.2 - - - -3.262 - 1.805 0.573 - 61.9 1 2 1 -0.0078 21 0 0 0 2.59E+07 1.90E+07 - - - 6.3421 0.9999 221125_WJC_METTL3_EV_vs_WT_F09.17182.17182.4 4.97E-05 14/192 R.SDSPVPTAPTSGGPK[136.11]PSTASAVPELATDPELEK[136.11].K "sp|Q86U44|MTA70_HUMAN,tr|B4E349|B4E349_HUMAN,tr|F5H6D8|F5H6D8_HUMAN,tr|B4DTN4|B4DTN4_HUMAN" 4 3248.6271 0.01 134318 17182 4 3248.624508 813.1641 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 4.18 3096.7 - 593748 - - - -0.7973 - 2.24 0.421 - 66.8 1 2 0 -0.0026 33 0 0 0 3.19E+07 2.83E+09 - - - 3.1316 0.9998 221125_WJC_METTL3_EV_vs_WT_F09.17184.17184.3 5.05E-07 18/80 R.DSFDDRGPSLNPVLDYDHGSR.S "sp|P43243|MATR3_HUMAN,tr|A8MXP9|A8MXP9_HUMAN,tr|D6R991|D6R991_HUMAN,tr|A0A0R4J2E8|A0A0R4J2E8_HUMAN,tr|D6REM6|D6REM6_HUMAN" 5 2361.0622 1.36 134320 17184 3 2361.060058 788.028 Matrin-3 OS=Homo sapiens OX=9606 GN=MATR3 PE=1 SV=2 4.28 3097 - 259588 - - - -0.8928 - 3.196 0.423 - 303.2 1 2 1 -0.0021 21 0 0 0 2.59E+07 1.90E+07 - - - 6.0411 0.9999 221125_WJC_METTL3_EV_vs_WT_F09.17231.17231.3 2.86E-07 16/128 R.SDSPVPTAPTSGGPK[136.11]PSTASAVPELATDPELEK[136.11].K "sp|Q86U44|MTA70_HUMAN,tr|B4E349|B4E349_HUMAN,tr|F5H6D8|F5H6D8_HUMAN,tr|B4DTN4|B4DTN4_HUMAN" 4 3248.6271 0.02 134336 17231 3 3248.61701 1083.883 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 4.18 3103.4 - 1.33E+06 - - - -3.1053 - 2.839 0.573 - 109.1 1 2 0 -0.0101 33 0 0 0 1.17E+06 5.94E+07 - - - 7.3262 0.9999 221125_WJC_METTL3_EV_vs_WT_F09.17379.17379.2 2.29E-07 26-Sep R.VPTANVSVVDLTC[160.03]R.L "sp|P04406|G3P_HUMAN,tr|E7EUT5|E7EUT5_HUMAN" 2 1529.7872 1.32 134384 17379 2 1529.787577 765.9009 Glyceraldehyde-3-phosphate dehydrogenase OS=Homo sapiens OX=9606 GN=GAPDH PE=1 SV=3 5.8 3124 - 73703.1 - - - 0.2608 - 2.127 0.58 - 204.6 1 2 0 0.0004 14 0 0 0 2.50E+06 1.89E+06 - - - 5.2187 0.9999 221125_WJC_METTL3_EV_vs_WT_F09.17381.17381.3 0.00121 Jul-52 K.K[136.11]GPGEVAGTVTGQK[136.11].R "sp|Q86U44|MTA70_HUMAN,tr|F5H6D8|F5H6D8_HUMAN,tr|H0YFV6|H0YFV6_HUMAN,tr|B4DTN4|B4DTN4_HUMAN" 4 1343.738 0.001 134385 17381 3 1343.736024 448.9199 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 8.59 3124.2 - 135617 - - - -1.4549 - 1.591 0.555 - 64 1 2 0 -0.002 14 0 0 0 0.00E+00 7.03E+06 - - - 5.9612 1 221125_WJC_METTL3_EV_vs_WT_F09.17387.17387.3 7.94E-09 14/84 K.DHTPSQELALTQSVGGDSSADR[166.11].L "sp|Q86U44|MTA70_HUMAN,tr|H0YFV6|H0YFV6_HUMAN" 2 2280.0494 0.001 134388 17387 3 2280.043212 761.0237 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 4.22 3125 - 167897 - - - -2.6995 - 3.309 0.565 - 185.7 1 2 0 -0.0062 22 0 0 0 0.00E+00 1.03E+07 - - - 7.6745 1 221125_WJC_METTL3_EV_vs_WT_F09.17402.17402.4 1.33E-14 27/186 R.QRHELLLGAGSGPGAGQQQATPGALLQAGPPR.C sp|Q96DI7|SNR40_HUMAN 1 3132.6541 2.81 134396 17402 4 3132.651541 784.1708 U5 small nuclear ribonucleoprotein 40 kDa protein OS=Homo sapiens OX=9606 GN=SNRNP40 PE=1 SV=1 9.61 3127 - 301710 - - - -0.8095 - 4.975 0.71 - 336.2 1 2 1 -0.0025 32 0 0 0 1.21E+07 4.31E+06 - - - 5.8896 1 221125_WJC_METTL3_EV_vs_WT_F09.17407.17407.4 1.87E-08 12/168 R.PQSC[160.03]HPC[160.03]C[160.03]YKPEAPGC[160.03]EAPDHLQGLGVPI.- sp|Q8N5Z5|KCD17_HUMAN 1 3273.4464 6.51 134399 17407 4 3273.444921 819.3689 BTB\POZ domain-containing protein KCTD17 OS=Homo sapiens OX=9606 GN=KCTD17 PE=1 SV=3 5.28 3127.7 - 245309 - - - -0.4503 - 2.505 0.676 - 29.2 1 1 0 -0.0015 29 0 0 0 1.03E+07 1.58E+06 - - - 5.3925 0.9937 221125_WJC_METTL3_EV_vs_WT_F09.17413.17413.4 0.0238 8/192 R.SDSPVPTAPTSGGPK[136.11]PSTASAVPELATDPELEK[136.11].K "sp|Q86U44|MTA70_HUMAN,tr|B4E349|B4E349_HUMAN,tr|F5H6D8|F5H6D8_HUMAN,tr|B4DTN4|B4DTN4_HUMAN" 4 3248.6271 0 134403 17413 4 3248.614632 813.1641 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 4.18 3128.5 - 190889 - - - -3.8373 - 1.641 0.302 - 20.8 1 2 0 -0.0125 33 0 0 0 3.02E+04 1.06E+07 - - - 1.9998 1 221125_WJC_METTL3_EV_vs_WT_F09.17437.17437.4 6.57E-10 16/186 R.QR[166.11]HELLLGAGSGPGAGQQQATPGALLQAGPPR[166.11].C sp|Q96DI7|SNR40_HUMAN 1 3152.6706 2.82 134417 17437 4 3152.66926 789.1749 U5 small nuclear ribonucleoprotein 40 kDa protein OS=Homo sapiens OX=9606 GN=SNRNP40 PE=1 SV=1 9.61 3131.6 - 146710 - - - -0.4304 - 3.485 0.658 - 104.5 1 2 1 -0.0014 32 0 0 0 1.23E+07 4.34E+06 - - - 5.3298 0.9994 221125_WJC_METTL3_EV_vs_WT_F09.17448.17448.3 8.39E-05 Jul-56 K.HKELAPYDENWFYTR.A "sp|P39019|RS19_HUMAN,tr|M0R140|M0R140_HUMAN,tr|M0R2L9|M0R2L9_HUMAN,tr|M0QYF7|M0QYF7_HUMAN" 4 1967.9166 1.09 134423 17448 3 1967.913887 656.9795 40S ribosomal protein S19 OS=Homo sapiens OX=9606 GN=RPS19 PE=1 SV=2 5.45 3133.1 - 120717 - - - -1.3847 - 1.748 0.462 - 57.1 1 2 1 -0.0027 15 0 0 0 1.08E+07 9.91E+06 - - - 5.1473 0.8826 221125_WJC_METTL3_EV_vs_WT_F09.17450.17450.4 0.386 May-84 K.HK[136.11]ELAPYDENWFYTR[166.11].A "sp|P39019|RS19_HUMAN,tr|M0R140|M0R140_HUMAN,tr|M0R2L9|M0R2L9_HUMAN,tr|M0QYF7|M0QYF7_HUMAN" 4 1985.9391 1.14 134425 17450 4 1985.933505 497.492 40S ribosomal protein S19 OS=Homo sapiens OX=9606 GN=RPS19 PE=1 SV=2 5.45 3133.3 - 80089 - - - -2.8082 - 0.983 0.215 - 24.1 1 2 1 -0.0056 15 0 0 0 6.91E+06 6.06E+06 - - - 1.0897 0.9997 221125_WJC_METTL3_EV_vs_WT_F09.17460.17460.3 6.11E-06 Oct-56 K.HK[136.11]ELAPYDENWFYTR[166.11].A "sp|P39019|RS19_HUMAN,tr|M0R140|M0R140_HUMAN,tr|M0R2L9|M0R2L9_HUMAN,tr|M0QYF7|M0QYF7_HUMAN" 4 1985.9391 1.11 134429 17460 3 1985.934132 662.987 40S ribosomal protein S19 OS=Homo sapiens OX=9606 GN=RPS19 PE=1 SV=2 5.45 3134.7 - 198723 - - - -2.4925 - 2.139 0.544 - 148.2 1 2 1 -0.005 15 0 0 0 1.08E+07 9.72E+06 - - - 6.5877 0.9886 221125_WJC_METTL3_EV_vs_WT_F09.17506.17506.4 0.0447 7/138 R.K[136.11]SPTMEQAVQTASAHLPAPAAVGR[166.11].R sp|Q8ND56|LS14A_HUMAN 1 2435.271 1.29 134448 17506 4 2435.273992 609.825 Protein LSM14 homolog A OS=Homo sapiens OX=9606 GN=LSM14A PE=1 SV=3 8.75 3141.3 - 104742 - - - 1.2294 - 0.807 0.226 - 10.5 1 2 0 0.003 24 0 0 0 8.25E+06 6.41E+06 - - - 1.1234 0.9963 221125_WJC_METTL3_EV_vs_WT_F09.17513.17513.4 0.00021 8/198 K.APSQALVQNIGQPTQGSPQPVGQQANNSPPVAQA.S sp|Q9Y5A9|YTHD2_HUMAN 1 3378.6916 - 134452 17513 4 3378.692615 845.6802 YTH domain-containing family protein 2 OS=Homo sapiens OX=9606 GN=YTHDF2 PE=1 SV=2 5.57 3142.3 - 107660 - - - 0.2871 - 2.078 0.526 - 21.5 1 1 0 0.001 34 0 0 0 - - - - - 4.0221 0.9636 221125_WJC_METTL3_EV_vs_WT_F09.17517.17517.3 0.0219 8/132 K.APSQALVQNIGQPTQGSPQPVGQQANNSPPVAQA.S sp|Q9Y5A9|YTHD2_HUMAN 1 3378.6916 - 134455 17517 3 3378.696589 1127.2378 YTH domain-containing family protein 2 OS=Homo sapiens OX=9606 GN=YTHDF2 PE=1 SV=2 5.57 3142.8 - 113826 - - - 1.4633 - 1.721 0.41 - 26.9 1 1 0 0.0049 34 0 0 0 - - - - - 4.3588 0.9984 221125_WJC_METTL3_EV_vs_WT_F09.17521.17521.4 0.00217 7/150 R.NALTALFTSSGRPPSQPNTQDKTPSK.V "sp|Q9ULV3|CIZ1_HUMAN,tr|Q5SYW2|Q5SYW2_HUMAN,tr|F5H2X7|F5H2X7_HUMAN,tr|H0Y5D5|H0Y5D5_HUMAN,tr|A0A494C0L7|A0A494C0L7_HUMAN,tr|Q9BTG3|Q9BTG3_HUMAN" 6 2742.3937 5.06 134457 17521 4 2742.398772 686.6057 Cip1-interacting zinc finger protein OS=Homo sapiens OX=9606 GN=CIZ1 PE=1 SV=2 9.99 3143.3 - 130025 - - - 1.8597 - 1.716 0.371 - 26.5 1 2 1 0.0051 26 0 0 0 5.62E+06 1.11E+06 - - - 2.6241 0.8322 221125_WJC_METTL3_EV_vs_WT_F09.17529.17529.3 0.0633 Jun-88 K.QSK[136.11]PVTTPEEIAQVATISANGDK[136.11].E "sp|P10809|CH60_HUMAN,tr|A0A7I2V599|A0A7I2V599_HUMAN,tr|E7EXB4|E7EXB4_HUMAN,tr|A0A7I2YQ71|A0A7I2YQ71_HUMAN,tr|E7ESH4|E7ESH4_HUMAN,tr|A0A7I2V5M1|A0A7I2V5M1_HUMAN,tr|A0A7I2V5K3|A0A7I2V5K3_HUMAN,tr|A0A7I2V369|A0A7I2V369_HUMAN" 8 2399.2515 1.83 134461 17529 3 2399.239587 800.7578 "60 kDa heat shock protein, mitochondrial OS=Homo sapiens OX=9606 GN=HSPD1 PE=1 SV=2" 4.68 3144.5 - 78976.3 - - - -4.9586 - 1.273 0.242 - 21 2 2 0 -0.0119 23 0 0 0 9.76E+06 5.35E+06 - - - 1.6617 0.9815 221125_WJC_METTL3_EV_vs_WT_F09.17572.17572.3 0.00242 Sep-76 R.FSGVPDRFSGSGSGTDFTLK.L "sp|A2NJV5|KV229_HUMAN,sp|A0A075B6S2|KVD29_HUMAN,sp|A0A0A0MRZ7|KVD26_HUMAN" 3 2060.9803 999 134483 17572 3 2060.985993 688.0007 Immunoglobulin kappa variable 2-29 OS=Homo sapiens OX=9606 GN=IGKV2-29 PE=3 SV=2 5.96 3150.5 - 87703.8 - - - 2.7458 - 1.75 0.291 - 65.8 1 2 1 0.0057 20 0 0 0 4.95E+06 0.00E+00 - - - 3.1404 0.9999 221125_WJC_METTL3_EV_vs_WT_F09.17600.17600.3 0.000167 Aug-52 K.K[136.11]GPGEVAGTVTGQK[136.11].R "sp|Q86U44|MTA70_HUMAN,tr|F5H6D8|F5H6D8_HUMAN,tr|H0YFV6|H0YFV6_HUMAN,tr|B4DTN4|B4DTN4_HUMAN" 4 1343.738 0 134496 17600 3 1343.740407 448.9199 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 8.59 3154.5 - 86252.4 - - - 1.8069 - 1.838 0.469 - 89.2 1 2 0 0.0024 14 0 0 0 7.16E+03 6.47E+06 - - - 5.3858 1 221125_WJC_METTL3_EV_vs_WT_F09.17608.17608.3 6.59E-11 18/84 K.DHTPSQELALTQSVGGDSSADR[166.11].L "sp|Q86U44|MTA70_HUMAN,tr|H0YFV6|H0YFV6_HUMAN" 2 2280.0494 0.01 134500 17608 3 2281.052812 761.0237 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 4.22 3155.9 - 98982.6 - - - 440.0979 - 3.923 0.626 - 345.9 1 2 0 1.0034 22 0 0 0 3.84E+04 7.34E+06 - - - 8.4819 0.9979 221125_WJC_METTL3_EV_vs_WT_F09.17625.17625.3 0.0101 Jul-52 R.KVESLQEEIAFLKK.L "sp|P08670|VIME_HUMAN,tr|B0YJC5|B0YJC5_HUMAN,tr|B0YJC4|B0YJC4_HUMAN" 3 1660.94 1.81 134507 17625 3 1660.943559 554.6539 Vimentin OS=Homo sapiens OX=9606 GN=VIM PE=1 SV=4 6.23 3158.4 - 64832.7 - - - 2.159 - 1.54 0.326 - 63.2 1 2 0 0.0036 14 0 0 0 3.09E+06 1.71E+06 - - - 3.3211 0.8983 221125_WJC_METTL3_EV_vs_WT_F09.17637.17637.2 0.561 22-Mar K.LNDLEDALQQAK.E sp|P04264|K2C1_HUMAN 1 1356.6885 101.83 134512 17637 2 1356.689009 679.3515 "Keratin, type II cytoskeletal 1 OS=Homo sapiens OX=9606 GN=KRT1 PE=1 SV=6" 4.03 3160.2 - 73081.2 - - - 0.3685 - 0.723 0.145 - 20.5 2 2 0 0.0005 12 0 0 0 5.00E+06 4.91E+04 - - - -0.8761 0.9932 221125_WJC_METTL3_EV_vs_WT_F09.17643.17643.3 0.0533 Mar-88 K.QSKPVTTPEEIAQVATISANGDK.E "sp|P10809|CH60_HUMAN,tr|A0A7I2V599|A0A7I2V599_HUMAN,tr|E7EXB4|E7EXB4_HUMAN,tr|A0A7I2YQ71|A0A7I2YQ71_HUMAN,tr|E7ESH4|E7ESH4_HUMAN,tr|A0A7I2V5M1|A0A7I2V5M1_HUMAN,tr|A0A7I2V5K3|A0A7I2V5K3_HUMAN,tr|A0A7I2V369|A0A7I2V369_HUMAN" 8 2383.2231 1.83 134515 17643 3 2383.224591 795.415 "60 kDa heat shock protein, mitochondrial OS=Homo sapiens OX=9606 GN=HSPD1 PE=1 SV=2" 4.68 3161.2 - 42950.4 - - - 0.6323 - 0.941 0.347 - 5 3 2 0 0.0015 23 0 0 0 9.76E+06 5.35E+06 - - - 2.0448 0.9665 221125_WJC_METTL3_EV_vs_WT_F09.17645.17645.2 3.45 16-Jun R.LLLPGELAK.H "sp|Q8N257|H2B3B_HUMAN,sp|A0A2R8Y619|H2BE1_HUMAN,sp|P33778|H2B1B_HUMAN,sp|Q96A08|H2B1A_HUMAN,sp|Q5QNW6|H2B2F_HUMAN,sp|P58876|H2B1D_HUMAN,sp|Q99880|H2B1L_HUMAN,sp|P62807|H2B1C_HUMAN,sp|Q99877|H2B1N_HUMAN,sp|P57053|H2BFS_HUMAN,sp|P23527|H2B1O_HUMAN,sp|O60814|H2B1K_HUMAN,sp|Q93079|H2B1H_HUMAN,sp|Q99879|H2B1M_HUMAN,sp|Q16778|H2B2E_HUMAN,sp|P06899|H2B1J_HUMAN,tr|U3KQK0|U3KQK0_HUMAN" 17 952.5957 19.79 134516 17645 2 952.597804 477.3051 Histone H2B type 3-B OS=Homo sapiens OX=9606 GN=H2BU1 PE=1 SV=3 6 3161.4 - 127289 - - - 2.1898 - 1.098 0.153 - 96.9 1 2 0 0.0021 9 0 0 0 5.42E+06 2.74E+05 - - - 0.4409 0.9997 221125_WJC_METTL3_EV_vs_WT_F09.17716.17716.3 0.00187 Jul-52 K.HTTSIFDDFSHYEK.R sp|Q9Y5A9|YTHD2_HUMAN 1 1725.7635 1.37 134554 17716 3 1725.767192 576.2618 YTH domain-containing family protein 2 OS=Homo sapiens OX=9606 GN=YTHDF2 PE=1 SV=2 5.21 3171.6 - 78679.1 - - - 2.1596 - 1.452 0.488 - 34.2 1 2 0 0.0037 14 0 0 0 2.01E+07 1.47E+07 - - - 4.9708 0.9999 221125_WJC_METTL3_EV_vs_WT_F09.17717.17717.3 0.000145 10/128 R.SDSPVPTAPTSGGPK[136.11]PSTASAVPELATDPELEK[136.11].K "sp|Q86U44|MTA70_HUMAN,tr|B4E349|B4E349_HUMAN,tr|F5H6D8|F5H6D8_HUMAN,tr|B4DTN4|B4DTN4_HUMAN" 4 3248.6271 0.02 134555 17717 3 3248.624162 1083.883 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 4.18 3171.8 - 132608 - - - -0.9038 - 1.866 0.49 - 46.3 1 2 0 -0.0029 33 0 0 0 8.62E+05 3.51E+07 - - - 5.4373 1 221125_WJC_METTL3_EV_vs_WT_F09.17730.17730.3 1.84E-08 13/52 K.HTTSIFDDFSHYEK[136.11].R sp|Q9Y5A9|YTHD2_HUMAN 1 1733.7777 1.37 134562 17730 3 1733.781482 578.9332 YTH domain-containing family protein 2 OS=Homo sapiens OX=9606 GN=YTHDF2 PE=1 SV=2 5.21 3173.5 - 183606 - - - 2.2016 - 2.509 0.582 - 149.7 1 2 0 0.0038 14 0 0 0 2.01E+07 1.47E+07 - - - 7.4723 0.9993 221125_WJC_METTL3_EV_vs_WT_F09.17732.17732.4 0.00463 Jun-78 K.HTTSIFDDFSHYEK[136.11].R sp|Q9Y5A9|YTHD2_HUMAN 1 1733.7777 1.5 134564 17732 4 1733.779161 434.4517 YTH domain-containing family protein 2 OS=Homo sapiens OX=9606 GN=YTHDF2 PE=1 SV=2 5.21 3173.8 - 60685.9 - - - 0.8629 - 1.082 0.342 - 16 1 2 0 0.0015 14 0 0 0 6.61E+06 4.42E+06 - - - 2.231 0.9991 221125_WJC_METTL3_EV_vs_WT_F09.17739.17739.4 0.00954 Aug-78 K.HTTSIFDDFSHYEK.R sp|Q9Y5A9|YTHD2_HUMAN 1 1725.7635 1.5 134567 17739 4 1725.76535 432.4481 YTH domain-containing family protein 2 OS=Homo sapiens OX=9606 GN=YTHDF2 PE=1 SV=2 5.21 3174.9 - 106075 - - - 1.0923 - 1.197 0.322 - 24.6 1 2 0 0.0019 14 0 0 0 6.61E+06 4.42E+06 - - - 2.0936 0.8403 221125_WJC_METTL3_EV_vs_WT_F09.17809.17809.3 0.275 Apr-80 R.QVQSLTC[160.03]EVDALKGTNESLER.Q "sp|P08670|VIME_HUMAN,tr|B0YJC5|B0YJC5_HUMAN,tr|B0YJC4|B0YJC4_HUMAN" 3 2376.1591 2.09 134600 17809 3 2376.156909 793.0603 Vimentin OS=Homo sapiens OX=9606 GN=VIM PE=1 SV=4 4.41 3184.6 - 67719.5 - - - -0.9238 - 1.023 0.215 - 11.9 1 2 1 -0.0022 21 0 0 0 1.28E+06 6.14E+05 - - - 0.9909 0.9855 221125_WJC_METTL3_EV_vs_WT_F09.17811.17811.3 0.00109 Jul-52 K.K[136.11]GPGEVAGTVTGQK[136.11].R "sp|Q86U44|MTA70_HUMAN,tr|F5H6D8|F5H6D8_HUMAN,tr|H0YFV6|H0YFV6_HUMAN,tr|B4DTN4|B4DTN4_HUMAN" 4 1343.738 0 134601 17811 3 1343.72875 448.9199 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 8.59 3184.8 - 90990.2 - - - -6.8682 - 1.454 0.434 - 45.6 1 2 0 -0.0092 14 0 0 0 7.90E+03 6.45E+06 - - - 4.3709 1 221125_WJC_METTL3_EV_vs_WT_F09.17827.17827.3 5.54E-08 17/84 K.DHTPSQELALTQSVGGDSSADR[166.11].L "sp|Q86U44|MTA70_HUMAN,tr|H0YFV6|H0YFV6_HUMAN" 2 2280.0494 0 134609 17827 3 2280.042713 761.0237 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 4.22 3187.1 - 144506 - - - -2.9184 - 3.228 0.639 - 299.7 1 2 0 -0.0067 22 0 0 0 2.49E+04 8.47E+06 - - - 8.4407 0.9007 221125_WJC_METTL3_EV_vs_WT_F09.17849.17849.3 0.661 3/104 R.NSQPHSPTSSLTSGGSLPLLQSPPSTR.L "sp|Q4VCS5|AMOT_HUMAN,tr|A6NP16|A6NP16_HUMAN,tr|E7ERM3|E7ERM3_HUMAN" 3 2732.3729 2.36 134615 17849 3 2732.379703 911.7983 Angiomotin OS=Homo sapiens OX=9606 GN=AMOT PE=1 SV=1 9.76 3190.6 - 45592.8 - - - 2.4766 - 0.916 0.238 - 6.4 1 2 0 0.0068 27 0 0 0 6.46E+06 2.73E+06 - - - 0.9897 0.8045 221125_WJC_METTL3_EV_vs_WT_F09.17854.17854.2 1.42 Feb-36 K.GSLGGGFSSGGFSGGSFSR.G "sp|P13645|K1C10_HUMAN,tr|A0A1B0GVI3|A0A1B0GVI3_HUMAN" 2 1706.7649 999 134618 17854 2 1706.76517 854.3897 "Keratin, type I cytoskeletal 10 OS=Homo sapiens OX=9606 GN=KRT10 PE=1 SV=6" 9.75 3191.2 - 22921.9 - - - 0.1805 - 0.592 0.161 - 4.9 5 2 0 0.0003 19 0 0 0 1.01E+06 0.00E+00 - - - -1.3711 0.9999 221125_WJC_METTL3_EV_vs_WT_F09.17861.17861.4 0.00143 7/138 K.KSPLALLAQTC[160.03]SQIGKPDPSPSSK.L sp|Q96F45|ZN503_HUMAN 1 2509.321 1.54 134620 17861 4 2509.320681 628.3375 Zinc finger protein 503 OS=Homo sapiens OX=9606 GN=ZNF503 PE=1 SV=1 9.2 3192.2 - 81130.9 - - - -0.1367 - 1.613 0.416 - 25.8 1 2 0 -0.0003 24 0 0 0 4.71E+07 3.06E+07 - - - 3.0002 0.9954 221125_WJC_METTL3_EV_vs_WT_F09.17864.17864.4 0.0383 5/138 K.K[136.11]SPLALLAQTC[160.03]SQIGK[136.11]PDPPPSSK[136.11].L sp|Q9H7S9|ZN703_HUMAN 1 2543.3844 1.65 134622 17864 4 2543.381333 636.8534 Zinc finger protein 703 OS=Homo sapiens OX=9606 GN=ZNF703 PE=1 SV=1 9.2 3192.6 - 70052.6 - - - -1.1901 - 1.089 0.252 - 11.5 1 2 0 -0.003 24 0 0 0 5.69E+07 3.45E+07 - - - 1.4459 0.9974 221125_WJC_METTL3_EV_vs_WT_F09.17894.17894.3 7.34E-06 Jul-76 K.HAASDVDLEIESLLNQQSTK[136.11].E "sp|Q86U44|MTA70_HUMAN,tr|F5H6D8|F5H6D8_HUMAN,tr|H0YFV6|H0YFV6_HUMAN,tr|B4DTN4|B4DTN4_HUMAN" 4 2205.1005 0.03 134634 17894 3 2206.100272 736.0408 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 4.31 3196.9 - 106019 - - - 453.4106 - 1.705 0.545 - 43.8 1 2 0 0.9998 20 0 0 0 9.19E+04 3.23E+06 - - - 5.6337 0.9923 221125_WJC_METTL3_EV_vs_WT_F09.17930.17930.2 0.153 16-Jul R.LLLPGELAK.H "sp|Q8N257|H2B3B_HUMAN,sp|A0A2R8Y619|H2BE1_HUMAN,sp|P33778|H2B1B_HUMAN,sp|Q96A08|H2B1A_HUMAN,sp|Q5QNW6|H2B2F_HUMAN,sp|P58876|H2B1D_HUMAN,sp|Q99880|H2B1L_HUMAN,sp|P62807|H2B1C_HUMAN,sp|Q99877|H2B1N_HUMAN,sp|P57053|H2BFS_HUMAN,sp|P23527|H2B1O_HUMAN,sp|O60814|H2B1K_HUMAN,sp|Q93079|H2B1H_HUMAN,sp|Q99879|H2B1M_HUMAN,sp|Q16778|H2B2E_HUMAN,sp|P06899|H2B1J_HUMAN,tr|U3KQK0|U3KQK0_HUMAN" 17 952.5957 1.71 134650 17930 2 952.5948 477.3051 Histone H2B type 3-B OS=Homo sapiens OX=9606 GN=H2BU1 PE=1 SV=3 6 3202 - 219138 - - - -0.9637 - 1.26 0.163 - 148.3 1 2 0 -0.0009 9 0 0 0 2.14E+07 1.25E+07 - - - 0.9132 1 221125_WJC_METTL3_EV_vs_WT_F09.17999.17999.3 1.95E-05 Aug-64 R.IINEPTAAAIAYGLDKK.G "sp|P54652|HSP72_HUMAN,sp|P11142|HSP7C_HUMAN,tr|E9PKE3|E9PKE3_HUMAN,tr|E9PN89|E9PN89_HUMAN,tr|E9PI65|E9PI65_HUMAN" 5 1786.9829 2.08 134671 17999 3 1786.980525 596.6682 Heat shock-related 70 kDa protein 2 OS=Homo sapiens OX=9606 GN=HSPA2 PE=1 SV=1 6.07 3212 - 168260 - - - -1.3291 - 2.16 0.544 - 50 1 2 0 -0.0024 17 0 0 0 2.21E+07 1.06E+07 - - - 6.5499 0.9981 221125_WJC_METTL3_EV_vs_WT_F09.18000.18000.3 0.00215 Sep-64 R.IINEPTAAAIAYGLDK[136.11]K[136.11].G "sp|P54652|HSP72_HUMAN,sp|P11142|HSP7C_HUMAN,tr|E9PKE3|E9PKE3_HUMAN,tr|E9PN89|E9PN89_HUMAN,tr|E9PI65|E9PI65_HUMAN" 5 1803.0113 2.08 134672 18000 3 1803.009432 602.011 Heat shock-related 70 kDa protein 2 OS=Homo sapiens OX=9606 GN=HSPA2 PE=1 SV=1 6.07 3212.1 - 91804.3 - - - -1.036 - 1.65 0.276 - 75.1 1 2 0 -0.0019 17 0 0 0 2.20E+07 1.06E+07 - - - 2.8817 0.9991 221125_WJC_METTL3_EV_vs_WT_F09.18023.18023.3 0.0119 Jun-52 K.K[136.11]GPGEVAGTVTGQK[136.11].R "sp|Q86U44|MTA70_HUMAN,tr|F5H6D8|F5H6D8_HUMAN,tr|H0YFV6|H0YFV6_HUMAN,tr|B4DTN4|B4DTN4_HUMAN" 4 1343.738 0.001 134684 18023 3 1343.736429 448.9199 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 8.59 3215.2 - 85614.2 - - - -1.1535 - 1.296 0.381 - 26.6 1 2 0 -0.0015 14 0 0 0 0.00E+00 7.67E+06 - - - 3.4764 0.8372 221125_WJC_METTL3_EV_vs_WT_F09.18025.18025.3 0.506 Apr-92 K.KSPLALLAQTC[160.03]SQIGKPDPPPSSK.L sp|Q9H7S9|ZN703_HUMAN 1 2519.3418 3.01 134685 18025 3 2519.345682 840.7879 Zinc finger protein 703 OS=Homo sapiens OX=9606 GN=ZNF703 PE=1 SV=1 9.2 3215.6 - 109501 - - - 1.5568 - 0.998 0.176 - 7.7 2 2 0 0.0039 24 0 0 0 1.29E+07 4.28E+06 - - - 0.3572 0.9999 221125_WJC_METTL3_EV_vs_WT_F09.18030.18030.4 5.88E-05 8/132 K.GRAEGEWEDQEALDYFSDKESGK.Q "sp|Q9NYF8|BCLF1_HUMAN,tr|E9PKI6|E9PKI6_HUMAN,tr|A0A1W2PQ43|A0A1W2PQ43_HUMAN,tr|E9PK91|E9PK91_HUMAN,tr|E9PK09|E9PK09_HUMAN,tr|E9PQN2|E9PQN2_HUMAN" 6 2645.1518 3.28 134688 18030 4 2645.146269 662.2952 Bcl-2-associated transcription factor 1 OS=Homo sapiens OX=9606 GN=BCLAF1 PE=1 SV=2 4.12 3216.3 - 96740.7 - - - -2.0793 - 2.11 0.611 - 36.8 1 2 2 -0.0055 23 0 0 0 2.16E+06 6.59E+05 - - - 4.7845 0.9994 221125_WJC_METTL3_EV_vs_WT_F09.18054.18054.4 0.00382 12/186 R.TPESSGSGSGGGGKRPAVPAAVSLLPPADPLR.Q sp|Q9H7S9|ZN703_HUMAN 1 2984.5679 1.94 134698 18054 4 2984.57115 747.1493 Zinc finger protein 703 OS=Homo sapiens OX=9606 GN=ZNF703 PE=1 SV=1 8.41 3219.6 - 148307 - - - 1.0729 - 1.965 0.409 - 39.9 1 2 1 0.0032 32 0 0 0 5.16E+06 2.67E+06 - - - 2.989 0.9999 221125_WJC_METTL3_EV_vs_WT_F09.18055.18055.4 1.51E-06 11/126 R.TKIDC[160.03]DNLEQYFIQQGGGPDKK.G "sp|Q92499|DDX1_HUMAN,tr|A0A7I2V2M5|A0A7I2V2M5_HUMAN,tr|A0A087X2G1|A0A087X2G1_HUMAN,tr|A0A7I2V430|A0A7I2V430_HUMAN,tr|A0A7I2V4F0|A0A7I2V4F0_HUMAN,tr|A0A087WZ71|A0A087WZ71_HUMAN,tr|A0A7I2YQ77|A0A7I2YQ77_HUMAN" 7 2553.217 1.19 134699 18055 4 2553.217109 639.3115 ATP-dependent RNA helicase DDX1 OS=Homo sapiens OX=9606 GN=DDX1 PE=1 SV=2 4.68 3219.7 - 143121 - - - 0.0611 - 2.567 0.586 - 77.8 1 2 1 0.0002 22 0 0 0 4.26E+06 3.58E+06 - - - 4.635 0.9981 221125_WJC_METTL3_EV_vs_WT_F09.18059.18059.4 0.00297 7/186 R.TPESSGSGSGGGGK[136.11]R[166.11]PAVPAAVSLLPPADPLR[166.11].Q sp|Q9H7S9|ZN703_HUMAN 1 3012.5987 1.97 134700 18059 4 3012.599463 754.1569 Zinc finger protein 703 OS=Homo sapiens OX=9606 GN=ZNF703 PE=1 SV=1 8.41 3220.5 - 73570.1 - - - 0.2573 - 1.656 0.344 - 16.1 1 2 1 0.0008 32 0 0 0 1.00E+07 5.10E+06 - - - 2.3723 0.9999 221125_WJC_METTL3_EV_vs_WT_F09.18061.18061.4 6.65E-08 17/138 K.KSPLALLAQTC[160.03]SQIGKPDPPPSSK.L sp|Q9H7S9|ZN703_HUMAN 1 2519.3418 1.64 134701 18061 4 2519.345136 630.8427 Zinc finger protein 703 OS=Homo sapiens OX=9606 GN=ZNF703 PE=1 SV=1 9.2 3220.7 - 298569 - - - 1.34 - 2.999 0.459 - 91.7 1 2 0 0.0034 24 0 0 0 5.68E+07 3.45E+07 - - - 3.5727 0.8629 221125_WJC_METTL3_EV_vs_WT_F09.18067.18067.4 1.42 3/138 K.K[136.11]SPLALLAQTC[160.03]SQIGK[136.11]PDPSPSSK[136.11].L sp|Q96F45|ZN503_HUMAN 1 2533.3636 1.54 134704 18067 4 2533.365609 634.3482 Zinc finger protein 503 OS=Homo sapiens OX=9606 GN=ZNF503 PE=1 SV=1 9.2 3221.6 - 62154.3 - - - 0.7835 - 0.832 0.154 - 3.5 2 2 0 0.002 24 0 0 0 4.73E+07 3.07E+07 - - - 0.2774 0.9997 221125_WJC_METTL3_EV_vs_WT_F09.18075.18075.3 0.000415 7/128 R.SDSPVPTAPTSGGPK[136.11]PSTASAVPELATDPELEK[136.11].K "sp|Q86U44|MTA70_HUMAN,tr|B4E349|B4E349_HUMAN,tr|F5H6D8|F5H6D8_HUMAN,tr|B4DTN4|B4DTN4_HUMAN" 4 3248.6271 0.001 134707 18075 3 3248.631406 1083.883 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 4.18 3222.7 - 76187 - - - 1.3261 - 1.597 0.443 - 22.4 1 2 0 0.0043 33 0 0 0 0.00E+00 3.86E+06 - - - 4.5548 0.9999 221125_WJC_METTL3_EV_vs_WT_F09.18082.18082.4 0.000167 8/138 K.K[136.11]SPLALLAQTC[160.03]SQIGK[136.11]PDPPPSSK[136.11].L sp|Q9H7S9|ZN703_HUMAN 1 2543.3844 1.64 134709 18082 4 2543.386434 636.8534 Zinc finger protein 703 OS=Homo sapiens OX=9606 GN=ZNF703 PE=1 SV=1 9.2 3223.7 - 109717 - - - 0.8154 - 1.889 0.481 - 24 1 2 0 0.0021 24 0 0 0 5.62E+07 3.42E+07 - - - 3.6162 0.9999 221125_WJC_METTL3_EV_vs_WT_F09.18098.18098.3 1.66E-05 Aug-88 K.EIETYHNLLEGGQEDFESSGAGK.L "sp|P35527|K1C9_HUMAN,tr|K7EQQ3|K7EQQ3_HUMAN" 2 2509.1245 999 134716 18098 3 2509.129401 837.3821 "Keratin, type I cytoskeletal 9 OS=Homo sapiens OX=9606 GN=KRT9 PE=1 SV=3" 4.14 3226 - 45539 - - - 1.9565 - 1.964 0.523 - 48 1 2 0 0.0049 23 0 0 0 1.42E+07 0.00E+00 - - - 5.953 0.9776 221125_WJC_METTL3_EV_vs_WT_F09.18136.18136.2 0.795 16-Mar R.LGSLVDEFK[136.11].E "sp|P12956|XRCC6_HUMAN,tr|B1AHC9|B1AHC9_HUMAN" 2 1014.5477 0.38 134731 18136 2 1014.547988 508.2811 X-ray repair cross-complementing protein 6 OS=Homo sapiens OX=9606 GN=XRCC6 PE=1 SV=2 4.37 3232.2 - 46098.7 - - - 0.272 - 0.696 0.286 - 19.1 1 2 0 0.0003 9 0 0 0 1.22E+06 3.23E+06 - - - 0.1049 0.9991 221125_WJC_METTL3_EV_vs_WT_F09.18141.18141.4 0.0131 4/156 K.IGEEQSAEDAEDGPPELLFIHGGHTAK.L "sp|Q16576|RBBP7_HUMAN,tr|Q5JNZ6|Q5JNZ6_HUMAN,tr|E9PC52|E9PC52_HUMAN" 3 2846.3359 2.55 134734 18141 4 2846.34262 712.5912 Histone-binding protein RBBP7 OS=Homo sapiens OX=9606 GN=RBBP7 PE=1 SV=1 4.24 3232.9 - 56752 - - - 2.3673 - 0.951 0.37 - 5.9 1 2 0 0.0067 27 0 0 0 1.47E+06 5.76E+05 - - - 2.4289 0.9997 221125_WJC_METTL3_EV_vs_WT_F09.18170.18170.4 0.0532 6/156 K.IGEEQSPEDAEDGPPELLFIHGGHTAK.L "sp|Q09028|RBBP4_HUMAN,tr|H0YCT5|H0YCT5_HUMAN,tr|H0YDK2|H0YDK2_HUMAN,tr|H0YEU5|H0YEU5_HUMAN,tr|H0YF10|H0YF10_HUMAN" 5 2872.3515 1.17 134747 18170 4 2872.357555 719.0952 Histone-binding protein RBBP4 OS=Homo sapiens OX=9606 GN=RBBP4 PE=1 SV=3 4.24 3237.1 - 63215.5 - - - 2.0969 - 1.614 0.398 - 17.3 1 2 0 0.006 27 0 0 0 5.30E+06 4.53E+06 - - - 2.8383 0.8459 221125_WJC_METTL3_EV_vs_WT_F09.18173.18173.2 0.00542 18-Jun G.VADLLPPDDK[136.11].Q "sp|P21860|ERBB3_HUMAN,tr|B4DGQ7|B4DGQ7_HUMAN" 2 1089.5797 0.08 134749 18173 2 1089.582307 545.7971 Receptor tyrosine-protein kinase erbB-3 OS=Homo sapiens OX=9606 GN=ERBB3 PE=1 SV=1 3.93 3237.5 - 71898.9 - - - 2.356 - 1.46 0.304 - 95.3 1 1 0 0.0026 10 0 0 0 1.51E+05 1.86E+06 - - - 2.3419 0.9992 221125_WJC_METTL3_EV_vs_WT_F09.18174.18174.4 0.00161 7/132 K.DFDFESANAQFNKEEIDREFHNK.L "sp|Q8ND56|LS14A_HUMAN,tr|A0A140TA76|A0A140TA76_HUMAN,tr|K7EMZ9|K7EMZ9_HUMAN" 3 2829.2631 1 134750 18174 4 2829.270394 708.323 Protein LSM14 homolog A OS=Homo sapiens OX=9606 GN=LSM14A PE=1 SV=3 4.43 3237.6 - 55492.6 - - - 2.5954 - 1.266 0.46 - 12.8 1 2 2 0.0073 23 0 0 0 2.53E+07 2.52E+07 - - - 3.3042 0.9999 221125_WJC_METTL3_EV_vs_WT_F09.18184.18184.4 0.00146 7/156 K.IGEEQSPEDAEDGPPELLFIHGGHTAK[136.11].L "sp|Q09028|RBBP4_HUMAN,tr|H0YCT5|H0YCT5_HUMAN,tr|H0YDK2|H0YDK2_HUMAN,tr|H0YEU5|H0YEU5_HUMAN,tr|H0YF10|H0YF10_HUMAN" 5 2880.3657 1.98 134755 18184 4 2880.365112 721.0987 Histone-binding protein RBBP4 OS=Homo sapiens OX=9606 GN=RBBP4 PE=1 SV=3 4.24 3239 - 65599.7 - - - -0.2153 - 1.788 0.437 - 22 1 2 0 -0.0006 27 0 0 0 5.19E+06 2.62E+06 - - - 3.2113 0.9999 221125_WJC_METTL3_EV_vs_WT_F09.18187.18187.4 0.0219 13/132 K.DFDFESANAQFNK[136.11]EEIDR[166.11]EFHNK[136.11].L "sp|Q8ND56|LS14A_HUMAN,tr|A0A140TA76|A0A140TA76_HUMAN,tr|K7EMZ9|K7EMZ9_HUMAN" 3 2855.2997 0.99 134756 18187 4 2855.302365 714.8322 Protein LSM14 homolog A OS=Homo sapiens OX=9606 GN=LSM14A PE=1 SV=3 4.43 3239.4 - 258100 - - - 0.926 - 2.415 0.516 - 47.7 1 2 2 0.0026 23 0 0 0 2.48E+07 2.50E+07 - - - 4.0022 0.983 221125_WJC_METTL3_EV_vs_WT_F09.18193.18193.4 0.00121 5/126 K.HTDESLGDC[160.03]SFLNTC[160.03]FHMDTC[160.03]K[136.11].Y "sp|Q86U44|MTA70_HUMAN,tr|H0YFV6|H0YFV6_HUMAN" 2 2682.0698 0.001 134758 18193 4 2683.0579 671.5247 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 4.64 3240.4 - 58525.4 - - - 368.3931 - 1.416 0.59 - 16.8 1 2 0 0.9881 22 0 0 0 0.00E+00 2.52E+06 - - - 4.2015 0.9999 221125_WJC_METTL3_EV_vs_WT_F09.18208.18208.3 1.19E-05 14/52 K.NKLNDLEDALQQAK.E sp|P04264|K2C1_HUMAN 1 1598.8264 313 134763 18208 3 1598.827703 533.9494 "Keratin, type II cytoskeletal 1 OS=Homo sapiens OX=9606 GN=KRT1 PE=1 SV=6" 4.56 3242.8 - 177139 - - - 0.815 - 2.259 0.515 - 235.1 1 2 1 0.0013 14 0 0 0 1.34E+07 4.29E+04 - - - 6.4471 0.9949 221125_WJC_METTL3_EV_vs_WT_F09.18218.18218.2 0.0267 26-Jul K.NKLNDLEDALQQAK.E sp|P04264|K2C1_HUMAN 1 1598.8264 999 134767 18218 2 1598.826018 800.4205 "Keratin, type II cytoskeletal 1 OS=Homo sapiens OX=9606 GN=KRT1 PE=1 SV=6" 4.56 3244.1 - 72240.3 - - - -0.2389 - 1.638 0.382 - 120.5 1 2 1 -0.0004 14 0 0 0 3.10E+06 0.00E+00 - - - 3.1007 0.9999 221125_WJC_METTL3_EV_vs_WT_F09.18230.18230.3 0.000248 Jul-52 K.K[136.11]GPGEVAGTVTGQK[136.11].R "sp|Q86U44|MTA70_HUMAN,tr|F5H6D8|F5H6D8_HUMAN,tr|H0YFV6|H0YFV6_HUMAN,tr|B4DTN4|B4DTN4_HUMAN" 4 1343.738 0.01 134773 18230 3 1343.739841 448.9199 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 8.59 3246 - 60885.7 - - - 1.3857 - 1.537 0.506 - 63.7 1 2 0 0.0019 14 0 0 0 2.50E+04 3.60E+06 - - - 5.3232 0.9995 221125_WJC_METTL3_EV_vs_WT_F09.18302.18302.3 4.71E-08 Aug-84 K.DHTPSQELALTQSVGGDSSADR[166.11].L "sp|Q86U44|MTA70_HUMAN,tr|H0YFV6|H0YFV6_HUMAN" 2 2280.0494 0.01 134811 18302 3 2281.050423 761.0237 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 4.22 3256.1 - 86428.1 - - - 439.0501 - 2.204 0.65 - 48.8 1 2 0 1.0011 22 0 0 0 7.74E+04 1.24E+07 - - - 7.3832 0.9998 221125_WJC_METTL3_EV_vs_WT_F09.18319.18319.2 7.25E-05 18-Oct K.FAAQELIEVK[136.11].R "sp|Q86U44|MTA70_HUMAN,tr|F5H6D8|F5H6D8_HUMAN,tr|H0YFV6|H0YFV6_HUMAN,tr|B4DTN4|B4DTN4_HUMAN" 4 1154.6427 0.02 134820 18319 2 1154.643151 578.3286 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 4.53 3258.5 - 2.09E+06 - - - 0.4122 - 2.093 0.465 - 280.1 1 2 0 0.0005 10 0 0 0 2.11E+06 8.65E+07 - - - 4.537 0.9811 221125_WJC_METTL3_EV_vs_WT_F09.18354.18354.3 0.077 Apr-52 K.HTTSIFDDFAHYEK[136.11].R "sp|Q9BYJ9|YTHD1_HUMAN,sp|Q7Z739|YTHD3_HUMAN,tr|A0A087X0Q1|A0A087X0Q1_HUMAN,tr|A0A024R7W5|A0A024R7W5_HUMAN,tr|A0A087WY31|A0A087WY31_HUMAN" 5 1717.7828 1.53 134840 18354 3 1717.78606 573.6015 YTH domain-containing family protein 1 OS=Homo sapiens OX=9606 GN=YTHDF1 PE=1 SV=1 5.21 3263.7 - 51311.3 - - - 1.9269 - 0.899 0.317 - 11.2 1 2 0 0.0033 14 0 0 0 3.16E+06 2.06E+06 - - - 1.7904 0.9779 221125_WJC_METTL3_EV_vs_WT_F09.18359.18359.3 0.531 May-52 K.HTTSIFDDFAHYEK.R "sp|Q9BYJ9|YTHD1_HUMAN,sp|Q7Z739|YTHD3_HUMAN,tr|A0A087X0Q1|A0A087X0Q1_HUMAN,tr|A0A024R7W5|A0A024R7W5_HUMAN,tr|A0A087WY31|A0A087WY31_HUMAN" 5 1709.7686 1.52 134842 18359 3 1709.770906 570.9301 YTH domain-containing family protein 1 OS=Homo sapiens OX=9606 GN=YTHDF1 PE=1 SV=1 5.21 3264.4 - 49255.2 - - - 1.378 - 0.761 0.331 - 21.6 1 2 0 0.0024 14 0 0 0 3.18E+06 2.09E+06 - - - 1.5038 0.9959 221125_WJC_METTL3_EV_vs_WT_F09.18366.18366.3 0.00241 5/116 K.DSAHLMNGPISQTTSQTSSIPPLSQVPATK.V "sp|Q92615|LAR4B_HUMAN,tr|B5MCU2|B5MCU2_HUMAN,tr|X6RCG6|X6RCG6_HUMAN" 3 3092.5448 1.28 134847 18366 3 3092.553294 1031.8556 La-related protein 4B OS=Homo sapiens OX=9606 GN=LARP4B PE=1 SV=3 6.74 3265.4 - 44813.6 - - - 2.7372 - 1.247 0.367 - 9.6 1 2 0 0.0085 30 0 0 0 5.54E+06 4.33E+06 - - - 3.1372 0.9903 221125_WJC_METTL3_EV_vs_WT_F09.18388.18388.3 1.31 4/116 K.DSAHLMNGPISQTTSQTSSIPPLSQVPATK[136.11].V "sp|Q92615|LAR4B_HUMAN,tr|B5MCU2|B5MCU2_HUMAN,tr|X6RCG6|X6RCG6_HUMAN" 3 3100.559 1.28 134858 18388 3 3100.557272 1034.527 La-related protein 4B OS=Homo sapiens OX=9606 GN=LARP4B PE=1 SV=3 6.74 3268.6 - 39670.6 - - - -0.5667 - 1.033 0.288 - 8.6 1 2 0 -0.0018 30 0 0 0 5.54E+06 4.35E+06 - - - 1.8251 1 221125_WJC_METTL3_EV_vs_WT_F09.18401.18401.2 5.29E-08 Dec-32 K.GILFVGSGVSGGEEGAR[166.11].Y "sp|P52209|6PGD_HUMAN,tr|K7EMN2|K7EMN2_HUMAN,tr|K7EPF6|K7EPF6_HUMAN,tr|K7EM49|K7EM49_HUMAN" 4 1600.8085 0.09 134862 18401 2 1600.812144 801.4115 "6-phosphogluconate dehydrogenase, decarboxylating OS=Homo sapiens OX=9606 GN=PGD PE=1 SV=3" 4.53 3270.5 - 80835.7 - - - 2.3045 - 2.595 0.615 - 346.9 1 2 0 0.0037 17 0 0 0 5.01E+05 5.40E+06 - - - 5.9267 0.9558 221125_WJC_METTL3_EV_vs_WT_F09.18407.18407.3 0.00298 May-72 L.SSASTSSHNLQSIFNIGSR[166.11].G "sp|P43243|MATR3_HUMAN,tr|A8MXP9|A8MXP9_HUMAN,tr|D6R991|D6R991_HUMAN,tr|D6REK4|D6REK4_HUMAN,tr|A0A0R4J2E8|A0A0R4J2E8_HUMAN,tr|D6RCM3|D6RCM3_HUMAN,tr|D6R8Z5|D6R8Z5_HUMAN,tr|D6REM6|D6REM6_HUMAN" 8 2001.9744 1.28 134865 18407 3 2001.980411 668.3321 Matrin-3 OS=Homo sapiens OX=9606 GN=MATR3 PE=1 SV=2 9.49 3271.3 - 32464.8 - - - 3.027 - 1.331 0.524 - 20.3 1 1 0 0.0061 19 0 0 0 2.42E+06 1.88E+06 - - - 5.0829 0.9959 221125_WJC_METTL3_EV_vs_WT_F09.18433.18433.3 0.000148 Aug-80 K.ADRDESSPYAAMLAAQDVAQR.C "sp|P62263|RS14_HUMAN,tr|A0A2R8Y811|A0A2R8Y811_HUMAN,tr|E5RH77|E5RH77_HUMAN" 3 2264.0492 0.59 134877 18433 3 2264.060679 755.6903 40S ribosomal protein S14 OS=Homo sapiens OX=9606 GN=RPS14 PE=1 SV=3 4.23 3275 - 54483.2 - - - 5.0882 - 1.8 0.532 - 62.8 1 2 1 0.0115 21 0 0 0 2.63E+06 4.45E+06 - - - 5.8773 0.9999 221125_WJC_METTL3_EV_vs_WT_F09.18445.18445.3 0.00281 Jul-52 K.K[136.11]GPGEVAGTVTGQK[136.11].R "sp|Q86U44|MTA70_HUMAN,tr|F5H6D8|F5H6D8_HUMAN,tr|H0YFV6|H0YFV6_HUMAN,tr|B4DTN4|B4DTN4_HUMAN" 4 1343.738 0 134883 18445 3 1343.738705 448.9199 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 8.59 3276.7 - 74108 - - - 0.5403 - 1.462 0.492 - 66.6 1 2 0 0.0007 14 0 0 0 7.74E+03 8.30E+06 - - - 5.0345 0.9993 221125_WJC_METTL3_EV_vs_WT_F09.18479.18479.3 0.00098 Jun-64 R.K[136.11]K[136.11]DASDDLDDLNFFNQK[136.11].K sp|P20042|IF2B_HUMAN 1 2035.9913 0.82 134895 18479 3 2035.99115 679.671 Eukaryotic translation initiation factor 2 subunit 2 OS=Homo sapiens OX=9606 GN=EIF2S2 PE=1 SV=2 4.28 3281.9 - 58022.6 - - - -0.0737 - 1.51 0.464 - 36.2 1 2 1 -0.0001 17 0 0 0 3.58E+06 4.37E+06 - - - 4.7542 0.767 221125_WJC_METTL3_EV_vs_WT_F09.18484.18484.4 1.81 Apr-96 R.KKDASDDLDDLNFFNQK.K sp|P20042|IF2B_HUMAN 1 2011.9487 0.81 134898 18484 4 2011.952112 503.9945 Eukaryotic translation initiation factor 2 subunit 2 OS=Homo sapiens OX=9606 GN=EIF2S2 PE=1 SV=2 4.28 3282.6 - 63057.9 - - - 1.6959 - 0.729 0.169 - 3.9 1 2 1 0.0034 17 0 0 0 3.26E+06 4.04E+06 - - - 0.5863 0.9993 221125_WJC_METTL3_EV_vs_WT_F09.18487.18487.3 0.00205 Jun-64 R.KKDASDDLDDLNFFNQK.K sp|P20042|IF2B_HUMAN 1 2011.9487 0.82 134899 18487 3 2011.951775 671.6568 Eukaryotic translation initiation factor 2 subunit 2 OS=Homo sapiens OX=9606 GN=EIF2S2 PE=1 SV=2 4.28 3283.1 - 69411 - - - 1.5284 - 1.577 0.488 - 34 1 2 1 0.0031 17 0 0 0 3.61E+06 4.43E+06 - - - 5.1307 1 221125_WJC_METTL3_EV_vs_WT_F09.18507.18507.3 1.09E-08 Dec-84 K.DHTPSQELALTQSVGGDSSADR[166.11].L "sp|Q86U44|MTA70_HUMAN,tr|H0YFV6|H0YFV6_HUMAN" 2 2280.0494 0.01 134904 18507 3 2280.045915 761.0237 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 4.22 3286.4 - 77190.9 - - - -1.514 - 2.698 0.606 - 117.6 1 2 0 -0.0035 22 0 0 0 7.74E+04 1.23E+07 - - - 7.6484 0.9996 221125_WJC_METTL3_EV_vs_WT_F09.18525.18525.3 0.000895 May-72 R.TSQNSELNNMQDLVEDYKK.K sp|P35908|K22E_HUMAN 1 2255.0376 839.14 134909 18525 3 2255.04272 752.6865 "Keratin, type II cytoskeletal 2 epidermal OS=Homo sapiens OX=9606 GN=KRT2 PE=1 SV=2" 4.32 3289 - 99685.3 - - - 2.2745 - 1.428 0.48 - 11.4 1 2 0 0.0051 19 0 0 0 1.63E+07 1.94E+04 - - - 4.7654 0.9993 221125_WJC_METTL3_EV_vs_WT_F09.18576.18576.2 0.0104 14-Jul R.VDEIIWVK[136.11].T sp|Q86U44|MTA70_HUMAN 1 1008.5735 0.02 134935 18576 2 1008.574496 505.294 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 4.37 3296.6 - 144567 - - - 0.9548 - 1.65 0.327 - 171.4 1 2 0 0.001 8 0 0 0 1.03E+06 5.12E+07 - - - 2.9662 0.9998 221125_WJC_METTL3_EV_vs_WT_F09.18649.18649.3 0.000138 Jul-52 K.K[136.11]GPGEVAGTVTGQK[136.11].R "sp|Q86U44|MTA70_HUMAN,tr|F5H6D8|F5H6D8_HUMAN,tr|H0YFV6|H0YFV6_HUMAN,tr|B4DTN4|B4DTN4_HUMAN" 4 1343.738 0.001 134968 18649 3 1343.739451 448.9199 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 8.59 3307 - 86327 - - - 1.0955 - 1.423 0.486 - 72.6 1 2 0 0.0015 14 0 0 0 0.00E+00 2.76E+06 - - - 4.8955 0.999 221125_WJC_METTL3_EV_vs_WT_F09.18681.18681.2 0.00337 22-Apr R.GYISPYFINTSK[136.11].G "sp|P10809|CH60_HUMAN,tr|A0A7I2V2X6|A0A7I2V2X6_HUMAN,tr|A0A7I2V599|A0A7I2V599_HUMAN,tr|A0A7I2YQ71|A0A7I2YQ71_HUMAN,tr|E7ESH4|E7ESH4_HUMAN,tr|A0A7I2V5M1|A0A7I2V5M1_HUMAN,tr|A0A7I2V5K3|A0A7I2V5K3_HUMAN,tr|A0A7I2V369|A0A7I2V369_HUMAN" 8 1396.7118 1.66 134981 18681 2 1396.710863 699.3632 "60 kDa heat shock protein, mitochondrial OS=Homo sapiens OX=9606 GN=HSPD1 PE=1 SV=2" 8.5 3311.9 - 29327.8 - - - -0.683 - 1.111 0.426 - 37.2 1 2 0 -0.001 12 0 0 0 4.32E+06 2.61E+06 - - - 2.4641 1 221125_WJC_METTL3_EV_vs_WT_F09.18688.18688.3 1.04E-11 23/84 K.HTDESLGDC[160.03]SFLNTC[160.03]FHMDTC[160.03]K[136.11].Y "sp|Q86U44|MTA70_HUMAN,tr|H0YFV6|H0YFV6_HUMAN" 2 2682.0698 0 134985 18688 3 2683.069228 895.0306 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 4.64 3312.9 - 383829 - - - 372.6167 - 4.756 0.771 - 800 1 2 0 0.9994 22 0 0 0 1.25E+05 2.76E+07 - - - 10.5562 0.9349 221125_WJC_METTL3_EV_vs_WT_F09.18707.18707.3 0.021 5/100 R.SSSSSSASC[160.03]NVVGSSLSSFGVSGASR[166.11].N "sp|Q8IXZ3|SP8_HUMAN,tr|A0A087X0Q6|A0A087X0Q6_HUMAN" 2 2460.1062 1.78 134991 18707 3 2460.094004 821.0427 Transcription factor Sp8 OS=Homo sapiens OX=9606 GN=SP8 PE=1 SV=3 7.96 3315.7 - 30963.5 - - - -4.9697 - 1.299 0.285 - 17.9 1 2 0 -0.0122 26 0 0 0 1.53E+06 8.61E+05 - - - 2.3159 1 221125_WJC_METTL3_EV_vs_WT_F09.18715.18715.3 1.32E-08 Nov-84 K.DHTPSQELALTQSVGGDSSADR[166.11].L "sp|Q86U44|MTA70_HUMAN,tr|H0YFV6|H0YFV6_HUMAN" 2 2280.0494 0.02 134992 18715 3 2280.045168 761.0237 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 4.22 3317 - 79749 - - - -1.8416 - 2.456 0.588 - 109.2 1 2 0 -0.0042 22 0 0 0 1.12E+05 4.73E+06 - - - 7.2247 0.9989 221125_WJC_METTL3_EV_vs_WT_F09.18728.18728.3 0.00445 4/100 R.SSSSSSASC[160.03]NVVGSSLSSFGVSGASR.N "sp|Q8IXZ3|SP8_HUMAN,tr|A0A087X0Q6|A0A087X0Q6_HUMAN" 2 2450.098 1.78 134997 18728 3 2450.100156 817.7066 Transcription factor Sp8 OS=Homo sapiens OX=9606 GN=SP8 PE=1 SV=3 7.96 3318.9 - 46273.1 - - - 0.8963 - 1.193 0.404 - 10.2 2 2 0 0.0022 26 0 0 0 1.53E+06 8.61E+05 - - - 3.3103 0.976 221125_WJC_METTL3_EV_vs_WT_F09.18741.18741.2 1.47 14-Apr R.ILELDQFK[136.11].G "sp|P12956|XRCC6_HUMAN,tr|B1AHC9|B1AHC9_HUMAN" 2 1012.5684 0.34 135000 18741 2 1012.568646 507.2915 X-ray repair cross-complementing protein 6 OS=Homo sapiens OX=9606 GN=XRCC6 PE=1 SV=2 4.37 3321 - 48899.1 - - - 0.1965 - 0.84 0.208 - 39.7 1 2 0 0.0002 8 0 0 0 1.97E+06 5.87E+06 - - - 0.0514 1 221125_WJC_METTL3_EV_vs_WT_F09.18766.18766.4 3.86E-09 17/126 K.HTDESLGDC[160.03]SFLNTC[160.03]FHMDTC[160.03]K[136.11].Y "sp|Q86U44|MTA70_HUMAN,tr|H0YFV6|H0YFV6_HUMAN" 2 2682.0698 0.03 135009 18766 4 2683.071361 671.5247 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 4.64 3324.6 - 250696 - - - 373.412 - 3.724 0.725 - 214 1 2 0 1.0015 22 0 0 0 2.85E+06 1.04E+08 - - - 5.6892 0.9669 221125_WJC_METTL3_EV_vs_WT_F09.18768.18768.2 1.25 14-Apr K.VFLENVIR[166.11].D sp|P62805|H4_HUMAN 1 998.5788 1.9 135010 18768 2 998.579271 500.2967 Histone H4 OS=Homo sapiens OX=9606 GN=H4C1 PE=1 SV=2 5.97 3324.9 - 34203.9 - - - 0.4356 - 0.725 0.244 - 56.4 1 2 0 0.0004 8 0 0 0 1.36E+07 7.13E+06 - - - -0.1268 0.9938 221125_WJC_METTL3_EV_vs_WT_F09.18772.18772.2 0.45 14-Jun K.VFLENVIR.D sp|P62805|H4_HUMAN 1 988.5706 1.9 135012 18772 2 988.571209 495.2926 Histone H4 OS=Homo sapiens OX=9606 GN=H4C1 PE=1 SV=2 5.97 3325.6 - 76905.5 - - - 0.6504 - 1.222 0.189 - 145.3 1 2 0 0.0006 8 0 0 0 1.36E+07 7.16E+06 - - - 1.0414 0.9967 221125_WJC_METTL3_EV_vs_WT_F09.18845.18845.3 0.000482 Jul-44 R.AR[166.11]FEELNADLFR[166.11].G "sp|P54652|HSP72_HUMAN,sp|P11142|HSP7C_HUMAN,tr|E9PNE6|E9PNE6_HUMAN,tr|A8K7Q2|A8K7Q2_HUMAN,tr|E9PKE3|E9PKE3_HUMAN,tr|E9PN89|E9PN89_HUMAN" 6 1499.7636 0.19 135038 18845 3 1499.765655 500.9285 Heat shock-related 70 kDa protein 2 OS=Homo sapiens OX=9606 GN=HSPA2 PE=1 SV=1 4.68 3336.5 - 63998.4 - - - 1.3922 - 1.484 0.372 - 83.7 1 2 1 0.0021 12 0 0 0 1.42E+06 7.60E+06 - - - 3.781 0.9996 221125_WJC_METTL3_EV_vs_WT_F09.18852.18852.3 0.00548 Jun-52 K.K[136.11]GPGEVAGTVTGQK[136.11].R "sp|Q86U44|MTA70_HUMAN,tr|F5H6D8|F5H6D8_HUMAN,tr|H0YFV6|H0YFV6_HUMAN,tr|B4DTN4|B4DTN4_HUMAN" 4 1343.738 0 135041 18852 3 1343.7379 448.9199 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 8.59 3337.5 - 95553.9 - - - -0.0588 - 1.115 0.462 - 39.7 1 2 0 -0.0001 14 0 0 0 2.00E+04 7.18E+06 - - - 3.9801 0.978 221125_WJC_METTL3_EV_vs_WT_F09.18876.18876.3 0.0248 Oct-48 L.DGIHLLDPDVVAR[166.11].F sp|Q86U44|MTA70_HUMAN 1 1428.76 0.001 135052 18876 3 1428.758195 477.2606 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 4.41 3340.9 - 109420 - - - -1.2969 - 2.051 0.372 - 165.6 1 1 0 -0.0019 13 0 0 0 0.00E+00 3.94E+06 - - - 4.6345 0.9998 221125_WJC_METTL3_EV_vs_WT_F09.18897.18897.2 0.0172 18-Aug K.IDTIEIITDR.Q "sp|P22626|ROA2_HUMAN,tr|A0A7I2YQN4|A0A7I2YQN4_HUMAN,tr|A0A7I2V4N0|A0A7I2V4N0_HUMAN,tr|A0A024RA28|A0A024RA28_HUMAN,tr|A0A7I2V4N1|A0A7I2V4N1_HUMAN,tr|A0A7I2V4I6|A0A7I2V4I6_HUMAN,tr|A0A087WUI2|A0A087WUI2_HUMAN,tr|A0A7I2V4S4|A0A7I2V4S4_HUMAN,tr|A0A7I2V323|A0A7I2V323_HUMAN,tr|A0A7I2V3P1|A0A7I2V3P1_HUMAN,tr|A0A7I2V3P7|A0A7I2V3P7_HUMAN" 11 1187.6398 1.24 135062 18897 2 1187.638725 594.8272 Heterogeneous nuclear ribonucleoproteins A2\B1 OS=Homo sapiens OX=9606 GN=HNRNPA2B1 PE=1 SV=2 4.03 3343.8 - 74759.4 - - - -0.8782 - 1.983 0.409 - 208.6 1 2 0 -0.001 10 0 0 0 2.74E+06 2.21E+06 - - - 3.9725 1 221125_WJC_METTL3_EV_vs_WT_F09.18927.18927.3 3.39E-07 Oct-84 K.DHTPSQELALTQSVGGDSSADR[166.11].L "sp|Q86U44|MTA70_HUMAN,tr|H0YFV6|H0YFV6_HUMAN" 2 2280.0494 0.001 135073 18927 3 2280.049934 761.0237 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 4.22 3348.4 - 78326.6 - - - 0.2487 - 2.456 0.628 - 87.3 1 2 0 0.0006 22 0 0 0 0.00E+00 4.89E+06 - - - 7.6717 1 221125_WJC_METTL3_EV_vs_WT_F09.18975.18975.4 1.94E-05 8/126 K.HTDESLGDC[160.03]SFLNTC[160.03]FHMDTC[160.03]K[136.11].Y "sp|Q86U44|MTA70_HUMAN,tr|H0YFV6|H0YFV6_HUMAN" 2 2682.0698 0.02 135092 18975 4 2682.072608 671.5247 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 4.64 3355.6 - 43506.9 - - - 1.0305 - 1.869 0.662 - 29.6 1 2 0 0.0028 22 0 0 0 7.65E+04 3.48E+06 - - - 5.1919 0.9394 221125_WJC_METTL3_EV_vs_WT_F09.19005.19005.2 0.927 20-Apr K.QNGIITEYSIK.Y sp|P23468|PTPRD_HUMAN 1 1264.6663 172.74 135102 19005 2 1264.670064 633.3404 Receptor-type tyrosine-protein phosphatase delta OS=Homo sapiens OX=9606 GN=PTPRD PE=1 SV=2 6 3360.1 - 63080.8 - - - 2.9628 - 1.065 0.159 - 55.8 1 2 0 0.0037 11 0 0 0 7.90E+06 4.58E+04 - - - 0.3846 0.9791 221125_WJC_METTL3_EV_vs_WT_F09.19017.19017.3 0.269 May-48 R.KIEEIKDFLLTAR.R "sp|P63173|RL38_HUMAN,tr|J3KT73|J3KT73_HUMAN,tr|J3QL01|J3QL01_HUMAN,tr|J3KSP2|J3KSP2_HUMAN" 4 1574.9032 1.11 135109 19017 3 1574.903748 525.975 60S ribosomal protein L38 OS=Homo sapiens OX=9606 GN=RPL38 PE=1 SV=2 6.18 3361.8 - 35016.2 - - - 0.3518 - 1.072 0.319 - 30.2 1 2 1 0.0006 13 0 0 0 1.81E+07 1.63E+07 - - - 2.2849 0.9999 221125_WJC_METTL3_EV_vs_WT_F09.19048.19048.3 1.83E-06 13/48 R.K[136.11]IEEIK[136.11]DFLLTAR[166.11].R "sp|P63173|RL38_HUMAN,tr|J3KT73|J3KT73_HUMAN,tr|J3QL01|J3QL01_HUMAN,tr|J3KSP2|J3KSP2_HUMAN" 4 1600.9399 1.12 135115 19048 3 1600.937994 534.6539 60S ribosomal protein L38 OS=Homo sapiens OX=9606 GN=RPL38 PE=1 SV=2 6.18 3366.9 - 424993 - - - -1.1674 - 2.448 0.548 - 207 1 2 1 -0.0019 13 0 0 0 1.83E+07 1.64E+07 - - - 7.0765 0.9929 221125_WJC_METTL3_EV_vs_WT_F09.19050.19050.4 0.0455 Aug-72 R.K[136.11]IEEIK[136.11]DFLLTAR[166.11].R "sp|P63173|RL38_HUMAN,tr|J3KT73|J3KT73_HUMAN,tr|J3QL01|J3QL01_HUMAN,tr|J3KSP2|J3KSP2_HUMAN" 4 1600.9399 1.25 135116 19050 4 1600.935191 401.2422 60S ribosomal protein L38 OS=Homo sapiens OX=9606 GN=RPL38 PE=1 SV=2 6.18 3367.1 - 117134 - - - -2.9183 - 1.609 0.328 - 53.9 1 2 1 -0.0047 13 0 0 0 4.07E+06 3.24E+06 - - - 2.256 1 221125_WJC_METTL3_EV_vs_WT_F09.19138.19138.3 9.94E-10 Nov-84 K.DHTPSQELALTQSVGGDSSADR[166.11].L "sp|Q86U44|MTA70_HUMAN,tr|H0YFV6|H0YFV6_HUMAN" 2 2280.0494 0 135155 19138 3 2281.044614 761.0237 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 4.22 3379.4 - 62681.5 - - - 436.5024 - 2.754 0.703 - 87.1 1 2 0 0.9952 22 0 0 0 1.05E+04 4.54E+06 - - - 8.5039 0.9996 221125_WJC_METTL3_EV_vs_WT_F09.19139.19139.3 0.000828 May-52 K.K[136.11]GPGEVAGTVTGQK[136.11].R "sp|Q86U44|MTA70_HUMAN,tr|F5H6D8|F5H6D8_HUMAN,tr|H0YFV6|H0YFV6_HUMAN,tr|B4DTN4|B4DTN4_HUMAN" 4 1343.738 0.001 135156 19139 3 1343.73788 448.9199 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 8.59 3379.5 - 50274.4 - - - -0.0737 - 1.244 0.446 - 19.2 1 2 0 -0.0001 14 0 0 0 0.00E+00 4.02E+06 - - - 4.0927 0.9238 221125_WJC_METTL3_EV_vs_WT_F09.19182.19182.3 0.00225 Jun-76 L.AISTPDAPATQDGVESLLQK[136.11].F "sp|Q86U44|MTA70_HUMAN,tr|B4E349|B4E349_HUMAN,tr|F5H6D8|F5H6D8_HUMAN,tr|H0YFV6|H0YFV6_HUMAN,tr|B4DTN4|B4DTN4_HUMAN" 5 2048.0517 0 135172 19182 3 2048.049257 683.6912 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 4.03 3386.2 - 52105.8 - - - -1.2002 - 1.324 0.389 - 32.2 1 1 0 -0.0025 20 0 0 0 8.55E+03 1.85E+06 - - - 3.5572 0.9996 221125_WJC_METTL3_EV_vs_WT_F09.19183.19183.3 0.000517 Jun-92 K.SQGLSQLYHNQSQGLLSQLQGQSK.D "sp|P78344|IF4G2_HUMAN,tr|D3DQV9|D3DQV9_HUMAN" 2 2628.3256 3.35 135173 19183 3 2628.330767 877.1158 Eukaryotic translation initiation factor 4 gamma 2 OS=Homo sapiens OX=9606 GN=EIF4G2 PE=1 SV=1 8.33 3386.4 - 45033 - - - 1.9689 - 1.469 0.459 - 25.4 1 2 0 0.0052 24 0 0 0 4.79E+05 1.43E+05 - - - 4.5492 0.9996 221125_WJC_METTL3_EV_vs_WT_F09.19188.19188.3 1.18E-05 Jul-64 R.DLIGHIVEFSQDQHGSR[166.11].F "sp|Q8TB72|PUM2_HUMAN,tr|A0A0C4DG68|A0A0C4DG68_HUMAN" 2 1946.9474 1.69 135174 19188 3 1946.952479 649.9897 Pumilio homolog 2 OS=Homo sapiens OX=9606 GN=PUM2 PE=1 SV=2 5.21 3387.2 - 26935 - - - 2.6046 - 1.815 0.445 - 44.4 1 2 0 0.0051 17 0 0 0 1.69E+06 9.99E+05 - - - 5.0058 0.9995 221125_WJC_METTL3_EV_vs_WT_F09.19305.19305.2 2.00E-08 26-Dec R.GVVDSEDIPLNLSR.E "sp|Q12931|TRAP1_HUMAN,sp|P08238|HS90B_HUMAN,sp|Q58FF7|H90B3_HUMAN,sp|P07900|HS90A_HUMAN,tr|I3L0K7|I3L0K7_HUMAN,tr|I3L239|I3L239_HUMAN" 6 1512.7784 1.82 135203 19305 2 1512.773848 757.3965 "Heat shock protein 75 kDa, mitochondrial OS=Homo sapiens OX=9606 GN=TRAP1 PE=1 SV=3" 4.03 3405.8 - 359068 - - - -3.0004 - 2.549 0.48 - 401.5 1 2 0 -0.0045 14 0 0 0 1.97E+07 1.08E+07 - - - 4.9329 0.9765 221125_WJC_METTL3_EV_vs_WT_F09.19331.19331.3 0.0587 May-44 R.AR[166.11]FEELC[160.03]SDLFR[166.11].S "sp|P48741|HSP77_HUMAN,sp|P0DMV8|HS71A_HUMAN,sp|P0DMV9|HS71B_HUMAN,sp|P17066|HSP76_HUMAN,tr|V9GZ37|V9GZ37_HUMAN,tr|A0A0G2JIW1|A0A0G2JIW1_HUMAN" 6 1561.7462 0.02 135207 19331 3 1561.742378 521.5893 Putative heat shock 70 kDa protein 7 OS=Homo sapiens OX=9606 GN=HSPA7 PE=5 SV=2 4.68 3409.6 - 60008.7 - - - -2.4492 - 0.989 0.385 - 36.3 1 2 1 -0.0038 12 0 0 0 4.12E+04 1.75E+06 - - - 2.8006 0.995 221125_WJC_METTL3_EV_vs_WT_F09.19337.19337.3 0.00443 Jul-52 K.K[136.11]GPGEVAGTVTGQK[136.11].R "sp|Q86U44|MTA70_HUMAN,tr|F5H6D8|F5H6D8_HUMAN,tr|H0YFV6|H0YFV6_HUMAN,tr|B4DTN4|B4DTN4_HUMAN" 4 1343.738 0 135208 19337 3 1343.734051 448.9199 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 8.59 3410.6 - 55917.5 - - - -2.9232 - 1.231 0.357 - 44.8 1 2 0 -0.0039 14 0 0 0 4.48E+03 9.49E+06 - - - 3.0714 0.9979 221125_WJC_METTL3_EV_vs_WT_F09.19398.19398.4 0.016 7/150 K.QLPDK[136.11]WQHDLFDSGFGGGAGVETGGK[136.11].L "sp|Q86V81|THOC4_HUMAN,tr|E9PB61|E9PB61_HUMAN" 2 2718.3009 0.68 135232 19398 4 2718.300246 680.5825 THO complex subunit 4 OS=Homo sapiens OX=9606 GN=ALYREF PE=1 SV=3 4.66 3419.3 - 46715.7 - - - -0.2384 - 1.467 0.343 - 25.4 1 2 1 -0.0006 26 0 0 0 3.27E+06 4.77E+06 - - - 2.3322 0.9998 221125_WJC_METTL3_EV_vs_WT_F09.19406.19406.4 1.29E-05 9/150 K.QLPDKWQHDLFDSGFGGGAGVETGGK.L "sp|Q86V81|THOC4_HUMAN,tr|E9PB61|E9PB61_HUMAN" 2 2702.2725 0.68 135234 19406 4 2702.276216 676.5754 THO complex subunit 4 OS=Homo sapiens OX=9606 GN=ALYREF PE=1 SV=3 4.66 3420.6 - 66735.1 - - - 1.3774 - 1.776 0.498 - 46.7 1 2 1 0.0037 26 0 0 0 3.27E+06 4.77E+06 - - - 3.7407 1 221125_WJC_METTL3_EV_vs_WT_F09.19422.19422.3 1.51E-06 13/84 K.DHTPSQELALTQSVGGDSSADR[166.11].L "sp|Q86U44|MTA70_HUMAN,tr|H0YFV6|H0YFV6_HUMAN" 2 2280.0494 0.001 135241 19422 3 2280.050975 761.0237 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 4.22 3422.8 - 59528.5 - - - 0.7052 - 2.909 0.598 - 153.1 1 2 0 0.0016 22 0 0 0 0.00E+00 3.21E+06 - - - 7.7383 0.9755 221125_WJC_METTL3_EV_vs_WT_F09.19457.19457.3 0.00191 Jul-72 K.SKELTTEIDNNIEQISSYK.S "sp|P13645|K1C10_HUMAN,tr|A0A1B0GVI3|A0A1B0GVI3_HUMAN" 2 2211.0907 667.71 135257 19457 3 2211.093623 738.0375 "Keratin, type I cytoskeletal 10 OS=Homo sapiens OX=9606 GN=KRT10 PE=1 SV=6" 4.41 3427.7 - 45176.8 - - - 1.3342 - 1.255 0.292 - 45 1 2 1 0.0029 19 0 0 0 6.42E+06 9.61E+03 - - - 2.3527 0.9993 221125_WJC_METTL3_EV_vs_WT_F09.19510.19510.3 0.000248 Jul-64 R.AETEC[160.03]QNTEYQQLLDIK.L "sp|P13645|K1C10_HUMAN,tr|A0A1B0GVI3|A0A1B0GVI3_HUMAN" 2 2081.9576 999 135280 19510 3 2081.957858 694.9931 "Keratin, type I cytoskeletal 10 OS=Homo sapiens OX=9606 GN=KRT10 PE=1 SV=6" 4 3435.6 - 65734.9 - - - 0.1479 - 1.73 0.328 - 69.2 1 2 0 0.0003 17 0 0 0 2.05E+06 0.00E+00 - - - 3.5815 0.9999 221125_WJC_METTL3_EV_vs_WT_F09.19521.19521.4 0.00141 4/186 K.SIDDTSNFDEFPESDILKPTVATSNHPETDYK.N sp|Q15208|STK38_HUMAN 1 3611.6427 8.27 135282 19521 4 3611.643757 903.918 Serine\threonine-protein kinase 38 OS=Homo sapiens OX=9606 GN=STK38 PE=1 SV=1 4.02 3437.5 - 52393.5 - - - 0.2794 - 1.369 0.429 - 6.9 1 2 0 0.001 32 0 0 0 8.13E+06 9.83E+05 - - - 3.0546 0.9999 221125_WJC_METTL3_EV_vs_WT_F09.19544.19544.3 0.000127 Jul-52 K.K[136.11]GPGEVAGTVTGQK[136.11].R "sp|Q86U44|MTA70_HUMAN,tr|F5H6D8|F5H6D8_HUMAN,tr|H0YFV6|H0YFV6_HUMAN,tr|B4DTN4|B4DTN4_HUMAN" 4 1343.738 0 135289 19544 3 1343.737665 448.9199 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 8.59 3441.4 - 73718 - - - -0.2337 - 1.62 0.524 - 74.7 1 2 0 -0.0003 14 0 0 0 1.29E+04 5.83E+06 - - - 5.6641 0.9915 221125_WJC_METTL3_EV_vs_WT_F09.19574.19574.2 0.0157 26-Apr R.FTQAGSEVSALLGR.L "sp|P06576|ATPB_HUMAN,tr|F8W0P7|F8W0P7_HUMAN,tr|H0YH81|H0YH81_HUMAN" 3 1434.7467 177.15 135303 19574 2 1434.750888 718.3806 "ATP synthase subunit beta, mitochondrial OS=Homo sapiens OX=9606 GN=ATP5F1B PE=1 SV=3" 6 3445.7 - 40395.6 - - - 2.9239 - 1.111 0.339 - 46.8 1 2 0 0.0042 14 0 0 0 1.83E+06 1.03E+04 - - - 1.8077 0.9655 221125_WJC_METTL3_EV_vs_WT_F09.19591.19591.4 0.308 7/138 K.QHNSGPNSKPVVSFIAGLTAPPGR.R sp|P53597|SUCA_HUMAN 1 2430.2768 2.17 135307 19591 4 2430.273984 608.5765 "Succinate--CoA ligase [ADP\GDP-forming] subunit alpha, mitochondrial OS=Homo sapiens OX=9606 GN=SUCLG1 PE=1 SV=4" 11 3448.5 - 80887 - - - -1.155 - 1.192 0.168 - 25 1 2 0 -0.0028 24 0 0 0 7.07E+06 3.26E+06 - - - 0.7439 0.994 221125_WJC_METTL3_EV_vs_WT_F09.19612.19612.2 0.0615 18-Apr R.EC[160.03]LNLWGYER[166.11].V sp|Q86U44|MTA70_HUMAN 1 1348.6109 0.01 135314 19612 2 1348.612563 675.3127 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 4.53 3451.7 - 40115.6 - - - 1.2027 - 1.156 0.243 - 79.3 1 2 0 0.0016 10 0 0 0 6.51E+04 9.41E+06 - - - 1.2399 0.9999 221125_WJC_METTL3_EV_vs_WT_F09.19621.19621.3 7.98E-09 Oct-84 K.DHTPSQELALTQSVGGDSSADR[166.11].L "sp|Q86U44|MTA70_HUMAN,tr|H0YFV6|H0YFV6_HUMAN" 2 2280.0494 0.001 135318 19621 3 2280.041713 761.0237 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 4.22 3453.1 - 70344.4 - - - -3.3569 - 2.298 0.615 - 90.3 1 2 0 -0.0077 22 0 0 0 0.00E+00 4.69E+06 - - - 7.3671 0.9994 221125_WJC_METTL3_EV_vs_WT_F09.19691.19691.2 0.00764 22-Jun K.DAGTIAGLNVLR.L "sp|P11142|HSP7C_HUMAN,tr|E9PQQ4|E9PQQ4_HUMAN,tr|E9PKE3|E9PKE3_HUMAN,tr|E9PN89|E9PN89_HUMAN,tr|E9PLF4|E9PLF4_HUMAN,tr|E9PI65|E9PI65_HUMAN,tr|E9PK54|E9PK54_HUMAN,tr|E9PQK7|E9PQK7_HUMAN" 8 1198.667 5.01 135347 19691 2 1198.666452 600.3408 Heat shock cognate 71 kDa protein OS=Homo sapiens OX=9606 GN=HSPA8 PE=1 SV=1 5.84 3462.8 - 77168.3 - - - -0.4455 - 1.521 0.375 - 116.6 1 2 0 -0.0005 12 0 0 0 3.12E+07 6.23E+06 - - - 2.914 0.977 221125_WJC_METTL3_EV_vs_WT_F09.19707.19707.3 0.845 3/132 R.QGSTSGSNVSAQAPAQSSSINLAASPAAAQLLNR.A "sp|Q8IXK0|PHC2_HUMAN,tr|A0A0A0MSI2|A0A0A0MSI2_HUMAN" 2 3253.6287 14.5 135352 19707 3 3253.626658 1085.5502 Polyhomeotic-like protein 2 OS=Homo sapiens OX=9606 GN=PHC2 PE=1 SV=1 9.75 3465.2 - 55511.8 - - - -0.6307 - 0.844 0.296 - 5.6 2 2 0 -0.0021 34 0 0 0 4.22E+06 2.91E+05 - - - 1.31 0.9981 221125_WJC_METTL3_EV_vs_WT_F09.19711.19711.2 0.000604 22-Jul K.DAGTIAGLNVLR[166.11].L "sp|P11142|HSP7C_HUMAN,tr|E9PQQ4|E9PQQ4_HUMAN,tr|E9PKE3|E9PKE3_HUMAN,tr|E9PN89|E9PN89_HUMAN,tr|E9PLF4|E9PLF4_HUMAN,tr|E9PI65|E9PI65_HUMAN,tr|E9PK54|E9PK54_HUMAN,tr|E9PQK7|E9PQK7_HUMAN" 8 1208.6753 5.01 135354 19711 2 1208.670591 605.3449 Heat shock cognate 71 kDa protein OS=Homo sapiens OX=9606 GN=HSPA8 PE=1 SV=1 5.84 3465.9 - 103184 - - - -3.8596 - 1.79 0.452 - 155.2 1 2 0 -0.0047 12 0 0 0 3.12E+07 6.23E+06 - - - 3.9099 0.9975 221125_WJC_METTL3_EV_vs_WT_F09.19756.19756.3 0.0213 May-52 K.K[136.11]GPGEVAGTVTGQK[136.11].R "sp|Q86U44|MTA70_HUMAN,tr|F5H6D8|F5H6D8_HUMAN,tr|H0YFV6|H0YFV6_HUMAN,tr|B4DTN4|B4DTN4_HUMAN" 4 1343.738 0.001 135370 19756 3 1343.736723 448.9199 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 8.59 3472.6 - 66311.3 - - - -0.9347 - 1.041 0.362 - 33 1 2 0 -0.0013 14 0 0 0 0.00E+00 5.28E+06 - - - 2.6824 0.9998 221125_WJC_METTL3_EV_vs_WT_F09.19771.19771.2 0.00075 22-May K.WELLQQVDTSTR.T sp|P04264|K2C1_HUMAN 1 1474.7416 999 135375 19771 2 1474.740403 738.3781 "Keratin, type II cytoskeletal 1 OS=Homo sapiens OX=9606 GN=KRT1 PE=1 SV=6" 4.37 3474.8 - 30768.8 - - - -0.8164 - 1.453 0.538 - 66.4 1 2 0 -0.0012 12 0 0 0 2.93E+06 0.00E+00 - - - 3.9974 0.9816 221125_WJC_METTL3_EV_vs_WT_F09.19805.19805.2 0.0189 16-May K.LLQDFFNGK[136.11].E "sp|P54652|HSP72_HUMAN,sp|P11142|HSP7C_HUMAN,sp|P17066|HSP76_HUMAN,tr|E9PNE6|E9PNE6_HUMAN,tr|A8K7Q2|A8K7Q2_HUMAN,tr|E9PKE3|E9PKE3_HUMAN,tr|E9PN89|E9PN89_HUMAN" 7 1088.5746 0.24 135386 19805 2 1088.573806 545.2946 Heat shock-related 70 kDa protein 2 OS=Homo sapiens OX=9606 GN=HSPA2 PE=1 SV=1 5.84 3479.8 - 64728.1 - - - -0.7248 - 0.829 0.239 - 63.2 1 2 0 -0.0008 9 0 0 0 9.57E+05 4.04E+06 - - - 0.2635 0.9978 221125_WJC_METTL3_EV_vs_WT_F09.19834.19834.3 1.83E-07 Oct-84 K.DHTPSQELALTQSVGGDSSADR[166.11].L "sp|Q86U44|MTA70_HUMAN,tr|H0YFV6|H0YFV6_HUMAN" 2 2280.0494 0 135395 19834 3 2281.045106 761.0237 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 4.22 3484 - 40850 - - - 436.7182 - 2.435 0.632 - 85.2 1 2 0 0.9957 22 0 0 0 1.27E+04 7.12E+06 - - - 7.4203 0.9963 221125_WJC_METTL3_EV_vs_WT_F09.19879.19879.2 6.23E-06 Nov-38 K.GNPQGFNQGLDC[160.03]DVIVAEVR[166.11].S sp|Q86U44|MTA70_HUMAN 1 2197.0461 0.001 135408 19879 2 2198.050485 1099.5303 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 4.03 3491 - 69469.6 - - - 457.1361 - 2.395 0.648 - 315 1 2 0 1.0043 20 0 0 0 0.00E+00 4.21E+06 - - - 5.659 0.9998 221125_WJC_METTL3_EV_vs_WT_F09.19893.19893.3 0.000616 8/124 R.GGGGSFGYSYGGGSGGGFSASSLGGGFGGGSR.G sp|P35527|K1C9_HUMAN 1 2704.1538 999 135415 19893 3 2704.161191 902.3919 "Keratin, type I cytoskeletal 9 OS=Homo sapiens OX=9606 GN=KRT9 PE=1 SV=3" 8.59 3492.9 - 75693.6 - - - 2.7203 - 1.626 0.552 - 35.6 1 2 0 0.0074 32 0 0 0 6.51E+06 0.00E+00 - - - 5.8106 0.9757 221125_WJC_METTL3_EV_vs_WT_F09.19905.19905.4 0.155 5/120 R.K[136.11]HAASDVDLEIESLLNQQSTK[136.11].E "sp|Q86U44|MTA70_HUMAN,tr|F5H6D8|F5H6D8_HUMAN,tr|H0YFV6|H0YFV6_HUMAN,tr|B4DTN4|B4DTN4_HUMAN" 4 2341.2096 0.01 135419 19905 4 2341.203267 586.3097 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 4.75 3494.4 - 49510.4 - - - -2.7131 - 1.122 0.219 - 10.4 1 2 0 -0.0064 21 0 0 0 2.24E+04 1.60E+06 - - - 1.1685 0.9095 221125_WJC_METTL3_EV_vs_WT_F09.19954.19954.2 11.8 20-Apr K.GFAFVQYVNER[166.11].N "sp|P07910|HNRPC_HUMAN,tr|G3V251|G3V251_HUMAN,tr|B4DY08|B4DY08_HUMAN,tr|G3V575|G3V575_HUMAN,tr|B4DSU6|B4DSU6_HUMAN,tr|G3V3K6|G3V3K6_HUMAN,tr|B2R5W2|B2R5W2_HUMAN,tr|G3V4C1|G3V4C1_HUMAN,tr|G3V576|G3V576_HUMAN,tr|G3V5X6|G3V5X6_HUMAN,tr|G3V4W0|G3V4W0_HUMAN,tr|G3V555|G3V555_HUMAN,tr|G3V4M8|G3V4M8_HUMAN,tr|G3V2Q1|G3V2Q1_HUMAN" 14 1338.6596 1.18 135433 19954 2 1338.657776 670.3371 Heterogeneous nuclear ribonucleoproteins C1\C2 OS=Homo sapiens OX=9606 GN=HNRNPC PE=1 SV=4 6 3502.3 - 26097.2 - - - -1.367 - 0.872 0.098 - 42.8 1 2 0 -0.0018 11 0 0 0 1.17E+06 9.93E+05 - - - -0.6063 0.9971 221125_WJC_METTL3_EV_vs_WT_F09.19961.19961.3 0.00872 May-52 K.K[136.11]GPGEVAGTVTGQK[136.11].R "sp|Q86U44|MTA70_HUMAN,tr|F5H6D8|F5H6D8_HUMAN,tr|H0YFV6|H0YFV6_HUMAN,tr|B4DTN4|B4DTN4_HUMAN" 4 1343.738 0 135434 19961 3 1343.732971 448.9199 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 8.59 3503.4 - 34629.9 - - - -3.7269 - 1.221 0.433 - 35.5 1 2 0 -0.005 14 0 0 0 7.56E+03 7.39E+06 - - - 3.8968 0.9999 221125_WJC_METTL3_EV_vs_WT_F09.19965.19965.2 2.21E-06 20-Aug K.GFAFVQYVNER.N "sp|P07910|HNRPC_HUMAN,tr|G3V251|G3V251_HUMAN,tr|B4DY08|B4DY08_HUMAN,tr|G3V575|G3V575_HUMAN,tr|B4DSU6|B4DSU6_HUMAN,tr|G3V3K6|G3V3K6_HUMAN,tr|B2R5W2|B2R5W2_HUMAN,tr|G3V4C1|G3V4C1_HUMAN,tr|G3V576|G3V576_HUMAN,tr|G3V5X6|G3V5X6_HUMAN,tr|G3V4W0|G3V4W0_HUMAN,tr|G3V555|G3V555_HUMAN,tr|G3V4M8|G3V4M8_HUMAN,tr|G3V2Q1|G3V2Q1_HUMAN" 14 1328.6513 1.18 135435 19965 2 1328.650103 665.3329 Heterogeneous nuclear ribonucleoproteins C1\C2 OS=Homo sapiens OX=9606 GN=HNRNPC PE=1 SV=4 6 3504 - 35356.9 - - - -0.928 - 1.906 0.589 - 349.7 1 2 0 -0.0012 11 0 0 0 1.17E+06 9.93E+05 - - - 5.1359 0.9457 221125_WJC_METTL3_EV_vs_WT_F09.19966.19966.2 0.36 30-Mar R.IINEPTAAAIAYGLDK.R "sp|P11021|BIP_HUMAN,sp|P54652|HSP72_HUMAN,sp|P34931|HS71L_HUMAN,sp|P11142|HSP7C_HUMAN,tr|E9PKE3|E9PKE3_HUMAN,tr|E9PN89|E9PN89_HUMAN,tr|A0A7P0TB36|A0A7P0TB36_HUMAN,tr|E9PLF4|E9PLF4_HUMAN,tr|A0A7P0TAI0|A0A7P0TAI0_HUMAN,tr|Q53FA3|Q53FA3_HUMAN,tr|E9PI65|E9PI65_HUMAN" 11 1658.8879 9.93 135436 19966 2 1658.887053 830.4512 Endoplasmic reticulum chaperone BiP OS=Homo sapiens OX=9606 GN=HSPA5 PE=1 SV=2 4.37 3504.1 - 25550.6 - - - -0.5329 - 0.759 0.158 - 22.4 1 2 0 -0.0009 16 0 0 0 3.19E+06 3.21E+05 - - - -0.4702 0.9998 221125_WJC_METTL3_EV_vs_WT_F09.20016.20016.2 1.17E-05 22-Jul K.SLNNQFASFIDK.V sp|P04264|K2C1_HUMAN 1 1382.683 18.56 135449 20016 2 1382.684549 692.3488 "Keratin, type II cytoskeletal 1 OS=Homo sapiens OX=9606 GN=KRT1 PE=1 SV=6" 5.55 3511.9 - 73363.2 - - - 1.0986 - 1.509 0.59 - 125.1 1 2 0 0.0015 12 0 0 0 1.00E+07 5.42E+05 - - - 4.4809 0.9996 221125_WJC_METTL3_EV_vs_WT_F09.20041.20041.3 0.00442 Jun-84 K.DHTPSQELALTQSVGGDSSADR[166.11].L "sp|Q86U44|MTA70_HUMAN,tr|H0YFV6|H0YFV6_HUMAN" 2 2280.0494 0.001 135457 20041 3 2280.041772 761.0237 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 4.22 3515.5 - 77271.8 - - - -3.3311 - 1.682 0.498 - 24.3 1 2 0 -0.0076 22 0 0 0 0.00E+00 4.33E+06 - - - 5.3229 0.9319 221125_WJC_METTL3_EV_vs_WT_F09.20047.20047.3 1.21E-05 Sep-64 L.GNQLDGIHLLDPDVVAR[166.11].F sp|Q86U44|MTA70_HUMAN 1 1840.9671 0.01 135459 20047 3 1840.959943 614.663 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 4.41 3516.3 - 62417.7 - - - -3.8773 - 1.974 0.445 - 75.3 1 1 0 -0.0071 17 0 0 0 1.88E+05 2.46E+07 - - - 5.2174 0.9883 221125_WJC_METTL3_EV_vs_WT_F09.20081.20081.4 0.0444 4/144 K.HAASDVDLEIESLLNQQSTK[136.11]EQQSK[136.11].K "sp|Q86U44|MTA70_HUMAN,tr|F5H6D8|F5H6D8_HUMAN,tr|H0YFV6|H0YFV6_HUMAN,tr|B4DTN4|B4DTN4_HUMAN" 4 2813.4014 0.001 135473 20081 4 2813.396353 704.3576 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 4.5 3521.3 - 31167.9 - - - -1.7925 - 1.096 0.282 - 8.3 1 2 1 -0.005 25 0 0 0 0.00E+00 8.52E+05 - - - 1.7083 0.7875 221125_WJC_METTL3_EV_vs_WT_F09.20116.20116.2 0.552 14-Jun Y.LFALGVYR.T sp|P24390|ERD21_HUMAN 1 937.5385 151.39 135486 20116 2 937.536736 469.7765 ER lumen protein-retaining receptor 1 OS=Homo sapiens OX=9606 GN=KDELR1 PE=1 SV=1 8.75 3526.2 - 70918.6 - - - -1.9221 - 1.234 0.277 - 105.9 1 1 0 -0.0018 8 0 0 0 8.82E+06 5.83E+04 - - - 1.7205 0.9971 221125_WJC_METTL3_EV_vs_WT_F09.20246.20246.3 0.00173 Jun-52 K.K[136.11]GPGEVAGTVTGQK[136.11].R "sp|Q86U44|MTA70_HUMAN,tr|F5H6D8|F5H6D8_HUMAN,tr|H0YFV6|H0YFV6_HUMAN,tr|B4DTN4|B4DTN4_HUMAN" 4 1343.738 0 135505 20246 3 1343.732021 448.9199 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 8.59 3546.5 - 45570.6 - - - -4.4339 - 1.333 0.45 - 42 1 2 0 -0.006 14 0 0 0 2.56E+04 1.16E+07 - - - 4.3193 0.9997 221125_WJC_METTL3_EV_vs_WT_F09.20251.20251.3 3.50E-06 Jul-84 K.DHTPSQELALTQSVGGDSSADR[166.11].L "sp|Q86U44|MTA70_HUMAN,tr|H0YFV6|H0YFV6_HUMAN" 2 2280.0494 0.01 135506 20251 3 2280.041263 761.0237 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 4.22 3547.3 - 82433.3 - - - -3.5543 - 1.846 0.531 - 41.1 1 2 0 -0.0081 22 0 0 0 4.15E+04 7.86E+06 - - - 5.9112 0.9919 221125_WJC_METTL3_EV_vs_WT_F09.20288.20288.2 0.0123 26-Jun K.NIYVLQELDNPGAK[136.11].R "sp|P12956|XRCC6_HUMAN,tr|B1AHC9|B1AHC9_HUMAN" 2 1580.829 1.49 135515 20288 2 1580.8225 791.4218 X-ray repair cross-complementing protein 6 OS=Homo sapiens OX=9606 GN=XRCC6 PE=1 SV=2 4.37 3552.8 - 50128.4 - - - -4.0941 - 1.543 0.328 - 96.5 1 2 0 -0.0065 14 0 0 0 2.84E+06 1.91E+06 - - - 2.55 0.9991 221125_WJC_METTL3_EV_vs_WT_F09.20350.20350.2 0.0013 30-Jun R.IINEPTAAAIAYGLDR[166.11].T "sp|P0DMV8|HS71A_HUMAN,sp|P0DMV9|HS71B_HUMAN,sp|P17066|HSP76_HUMAN,tr|A0A0G2JIW1|A0A0G2JIW1_HUMAN" 4 1696.9024 0.03 135540 20350 2 1696.904295 849.4585 Heat shock 70 kDa protein 1A OS=Homo sapiens OX=9606 GN=HSPA1A PE=1 SV=1 4.37 3561.7 - 43179.2 - - - 1.1433 - 1.52 0.367 - 97.2 1 2 0 0.0019 16 0 0 0 5.13E+04 1.86E+06 - - - 2.7805 0.9995 221125_WJC_METTL3_EV_vs_WT_F09.20351.20351.2 2.10E-07 30-Aug K.SYELPDGQVITIGNER.F "sp|Q6S8J3|POTEE_HUMAN,sp|P63261|ACTG_HUMAN,sp|P68133|ACTS_HUMAN,sp|P62736|ACTA_HUMAN,sp|Q9BYX7|ACTBM_HUMAN,sp|P68032|ACTC_HUMAN,sp|Q562R1|ACTBL_HUMAN,sp|P60709|ACTB_HUMAN,sp|P63267|ACTH_HUMAN,sp|A5A3E0|POTEF_HUMAN,tr|A0A804GS07|A0A804GS07_HUMAN,tr|E7EVS6|E7EVS6_HUMAN,tr|A0A6Q8PFE4|A0A6Q8PFE4_HUMAN,tr|A0A2R8YEA7|A0A2R8YEA7_HUMAN,tr|A0A804HKV3|A0A804HKV3_HUMAN,tr|A0A2R8Y793|A0A2R8Y793_HUMAN,tr|I3L4N8|I3L4N8_HUMAN,tr|A6NL76|A6NL76_HUMAN" 18 1789.8846 12.13 135541 20351 2 1789.889803 895.9496 POTE ankyrin domain family member E OS=Homo sapiens OX=9606 GN=POTEE PE=2 SV=3 4.14 3561.9 - 39133.6 - - - 2.8829 - 1.889 0.608 - 175.6 1 2 0 0.0052 16 0 0 0 6.88E+06 5.67E+05 - - - 5.0938 0.81 221125_WJC_METTL3_EV_vs_WT_F09.20391.20391.2 3.39 18-Mar R.FEELC[160.03]SDLFR.S "sp|P48741|HSP77_HUMAN,sp|P0DMV8|HS71A_HUMAN,sp|P0DMV9|HS71B_HUMAN,sp|P17066|HSP76_HUMAN,tr|V9GZ37|V9GZ37_HUMAN,tr|A0A0G2JIW1|A0A0G2JIW1_HUMAN" 6 1314.5914 11.23 135548 20391 2 1314.58846 658.303 Putative heat shock 70 kDa protein 7 OS=Homo sapiens OX=9606 GN=HSPA7 PE=5 SV=2 4.14 3568.4 - 17179.2 - - - -2.2653 - 0.623 0.205 - 27 1 2 0 -0.003 10 0 0 0 1.51E+06 1.35E+05 - - - -0.7667 0.879 221125_WJC_METTL3_EV_vs_WT_F09.20402.20402.2 0.399 30-Mar K.SYELPDGQVITIGNER[166.11].F "sp|Q6S8J3|POTEE_HUMAN,sp|P63261|ACTG_HUMAN,sp|P68133|ACTS_HUMAN,sp|P62736|ACTA_HUMAN,sp|Q9BYX7|ACTBM_HUMAN,sp|P68032|ACTC_HUMAN,sp|Q562R1|ACTBL_HUMAN,sp|P60709|ACTB_HUMAN,sp|P63267|ACTH_HUMAN,sp|A5A3E0|POTEF_HUMAN,tr|A0A804GS07|A0A804GS07_HUMAN,tr|E7EVS6|E7EVS6_HUMAN,tr|A0A6Q8PFE4|A0A6Q8PFE4_HUMAN,tr|A0A2R8YEA7|A0A2R8YEA7_HUMAN,tr|A0A804HKV3|A0A804HKV3_HUMAN,tr|A0A2R8Y793|A0A2R8Y793_HUMAN,tr|I3L4N8|I3L4N8_HUMAN,tr|A6NL76|A6NL76_HUMAN" 18 1799.8929 11.86 135553 20402 2 1799.897819 900.9537 POTE ankyrin domain family member E OS=Homo sapiens OX=9606 GN=POTEE PE=2 SV=3 4.14 3570 - 24033 - - - 2.7257 - 0.651 0.245 - 20 1 2 0 0.0049 16 0 0 0 6.72E+06 5.67E+05 - - - -0.2063 0.8307 221125_WJC_METTL3_EV_vs_WT_F09.20415.20415.2 3.63 Mar-34 R.GSAAALC[160.03]NNLSVLQLPAR.N sp|Q9H977|WDR54_HUMAN 1 1853.9782 999 135557 20415 2 1853.978873 927.9964 WD repeat-containing protein 54 OS=Homo sapiens OX=9606 GN=WDR54 PE=1 SV=1 8.25 3572.1 - 28910.2 - - - 0.3813 - 0.714 0.111 - 12.9 4 2 0 0.0007 18 0 0 0 1.18E+07 0.00E+00 - - - -1.2365 0.9872 221125_WJC_METTL3_EV_vs_WT_F09.20452.20452.3 0.0571 May-52 K.K[136.11]GPGEVAGTVTGQK[136.11].R "sp|Q86U44|MTA70_HUMAN,tr|F5H6D8|F5H6D8_HUMAN,tr|H0YFV6|H0YFV6_HUMAN,tr|B4DTN4|B4DTN4_HUMAN" 4 1343.738 0.04 135571 20452 3 1343.736526 448.9199 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 8.59 3577.4 - 70738.4 - - - -1.0813 - 1.006 0.28 - 32.1 1 2 0 -0.0015 14 0 0 0 2.93E+05 6.58E+06 - - - 1.6772 0.8619 221125_WJC_METTL3_EV_vs_WT_F09.20461.20461.2 3.72 18-Mar R.FEELNADLFR.G "sp|P54652|HSP72_HUMAN,sp|P11142|HSP7C_HUMAN,tr|E9PNE6|E9PNE6_HUMAN,tr|A8K7Q2|A8K7Q2_HUMAN,tr|E9PKE3|E9PKE3_HUMAN,tr|E9PN89|E9PN89_HUMAN" 6 1252.6088 0.42 135574 20461 2 1252.609281 627.3117 Heat shock-related 70 kDa protein 2 OS=Homo sapiens OX=9606 GN=HSPA2 PE=1 SV=1 4.14 3578.8 - 15750 - - - 0.3824 - 0.611 0.187 - 21.5 2 2 0 0.0005 10 0 0 0 7.68E+05 1.84E+06 - - - -1.0876 1 221125_WJC_METTL3_EV_vs_WT_F09.20484.20484.3 4.12E-07 Sep-84 K.DHTPSQELALTQSVGGDSSADR[166.11].L "sp|Q86U44|MTA70_HUMAN,tr|H0YFV6|H0YFV6_HUMAN" 2 2280.0494 0.001 135580 20484 3 2280.046412 761.0237 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 4.22 3582.4 - 52318 - - - -1.296 - 2.311 0.584 - 62.6 1 2 0 -0.003 22 0 0 0 0.00E+00 6.75E+06 - - - 7.0362 0.9995 221125_WJC_METTL3_EV_vs_WT_F09.20512.20512.3 4.38E-10 18/80 R.K[136.11]HAASDVDLEIESLLNQQSTK[136.11].E "sp|Q86U44|MTA70_HUMAN,tr|F5H6D8|F5H6D8_HUMAN,tr|H0YFV6|H0YFV6_HUMAN,tr|B4DTN4|B4DTN4_HUMAN" 4 2341.2096 0 135589 20512 3 2342.208193 781.4105 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 4.75 3586.6 - 157709 - - - 426.5205 - 3.954 0.602 - 476.9 1 2 0 0.9986 21 0 0 0 1.27E+05 3.26E+07 - - - 8.2709 0.9991 221125_WJC_METTL3_EV_vs_WT_F09.20531.20531.2 0.00299 Apr-34 K.SSGPTSLFAVTVAPPGAR.Q "sp|Q00839|HNRPU_HUMAN,tr|A0A1W2PP35|A0A1W2PP35_HUMAN,tr|A0A1W2PPS1|A0A1W2PPS1_HUMAN,tr|A0A1W2PP22|A0A1W2PP22_HUMAN,tr|A0A1X7SBS1|A0A1X7SBS1_HUMAN" 5 1713.905 1.07 135594 20531 2 1713.904169 857.9598 Heterogeneous nuclear ribonucleoprotein U OS=Homo sapiens OX=9606 GN=HNRNPU PE=1 SV=6 9.47 3589.7 - 30910.4 - - - -0.4755 - 1.156 0.422 - 27.1 1 2 0 -0.0008 18 0 0 0 2.41E+06 2.24E+06 - - - 2.514 0.9971 221125_WJC_METTL3_EV_vs_WT_F09.20533.20533.2 0.0156 Apr-34 K.SSGPTSLFAVTVAPPGAR[166.11].Q "sp|Q00839|HNRPU_HUMAN,tr|A0A1W2PP35|A0A1W2PP35_HUMAN,tr|A0A1W2PPS1|A0A1W2PPS1_HUMAN,tr|A0A1W2PP22|A0A1W2PP22_HUMAN,tr|A0A1X7SBS1|A0A1X7SBS1_HUMAN" 5 1723.9133 1.07 135595 20533 2 1723.914987 862.9639 Heterogeneous nuclear ribonucleoprotein U OS=Homo sapiens OX=9606 GN=HNRNPU PE=1 SV=6 9.47 3589.9 - 27246.4 - - - 1.0053 - 1.013 0.357 - 32.7 1 2 0 0.0017 18 0 0 0 2.41E+06 2.24E+06 - - - 1.709 1 221125_WJC_METTL3_EV_vs_WT_F09.20562.20562.4 3.30E-10 17/120 R.K[136.11]HAASDVDLEIESLLNQQSTK[136.11].E "sp|Q86U44|MTA70_HUMAN,tr|F5H6D8|F5H6D8_HUMAN,tr|H0YFV6|H0YFV6_HUMAN,tr|B4DTN4|B4DTN4_HUMAN" 4 2341.2096 0.01 135599 20562 4 2341.206406 586.3097 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 4.75 3594.7 - 383818 - - - -1.3724 - 3.633 0.511 - 231.2 1 2 0 -0.0032 21 0 0 0 4.36E+05 4.66E+07 - - - 4.0994 0.9999 221125_WJC_METTL3_EV_vs_WT_F09.20647.20647.3 0.0026 Jun-52 K.K[136.11]GPGEVAGTVTGQK[136.11].R "sp|Q86U44|MTA70_HUMAN,tr|F5H6D8|F5H6D8_HUMAN,tr|H0YFV6|H0YFV6_HUMAN,tr|B4DTN4|B4DTN4_HUMAN" 4 1343.738 0 135624 20647 3 1343.737513 448.9199 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 8.59 3607.9 - 43821.1 - - - -0.3468 - 1.502 0.531 - 43.3 1 2 0 -0.0005 14 0 0 0 5.48E+03 5.13E+06 - - - 5.5411 0.9975 221125_WJC_METTL3_EV_vs_WT_F09.20692.20692.3 1.29E-08 Aug-84 K.DHTPSQELALTQSVGGDSSADR[166.11].L "sp|Q86U44|MTA70_HUMAN,tr|H0YFV6|H0YFV6_HUMAN" 2 2280.0494 0 135637 20692 3 2281.04548 761.0237 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 4.22 3615 - 79245.7 - - - 436.8822 - 2.058 0.632 - 52.6 1 2 0 0.9961 22 0 0 0 9.13E+03 4.80E+06 - - - 7.0214 0.9963 221125_WJC_METTL3_EV_vs_WT_F09.20706.20706.3 3.96E-06 14/80 R.K[136.11]HAASDVDLEIESLLNQQSTK[136.11].E "sp|Q86U44|MTA70_HUMAN,tr|F5H6D8|F5H6D8_HUMAN,tr|H0YFV6|H0YFV6_HUMAN,tr|B4DTN4|B4DTN4_HUMAN" 4 2341.2096 0 135642 20706 3 2342.204797 781.4105 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 4.75 3617 - 142764 - - - 425.07 - 3.26 0.513 - 245.1 1 2 0 0.9952 21 0 0 0 3.89E+04 1.41E+07 - - - 6.8169 1 221125_WJC_METTL3_EV_vs_WT_F09.20708.20708.3 2.42E-10 11/124 R.KINSSPNVNTTASGVEDLNIIQVTIPDDDNER.L "sp|P78347|GTF2I_HUMAN,tr|A0A494C1K3|A0A494C1K3_HUMAN" 2 3467.7016 2.54 135643 20708 3 3467.696083 1156.9078 General transcription factor II-I OS=Homo sapiens OX=9606 GN=GTF2I PE=1 SV=2 3.96 3617.2 - 105644 - - - -1.591 - 2.142 0.685 - 51.9 1 2 0 -0.0055 32 0 0 0 5.60E+06 2.20E+06 - - - 7.928 0.9997 221125_WJC_METTL3_EV_vs_WT_F09.20722.20722.4 0.0393 4/186 R.KINSSPNVNTTASGVEDLNIIQVTIPDDDNER.L "sp|P78347|GTF2I_HUMAN,tr|A0A494C1K3|A0A494C1K3_HUMAN" 2 3467.7016 2.35 135648 20722 4 3467.70605 867.9327 General transcription factor II-I OS=Homo sapiens OX=9606 GN=GTF2I PE=1 SV=2 3.96 3619.2 - 46846.9 - - - 1.2833 - 0.968 0.386 - 5.2 1 2 0 0.0044 32 0 0 0 1.53E+06 6.53E+05 - - - 2.5747 0.9429 221125_WJC_METTL3_EV_vs_WT_F09.20729.20729.2 0.532 18-Apr K.QVSDLISVLR[166.11].E "sp|P17844|DDX5_HUMAN,tr|J3KTA4|J3KTA4_HUMAN,tr|A0A0G2JLI4|A0A0G2JLI4_HUMAN" 3 1138.6585 1.5 135650 20729 2 1138.65681 570.3365 Probable ATP-dependent RNA helicase DDX5 OS=Homo sapiens OX=9606 GN=DDX5 PE=1 SV=1 5.84 3620.6 - 17602.2 - - - -1.522 - 0.776 0.193 - 38.4 1 2 0 -0.0017 10 0 0 0 5.12E+05 3.41E+05 - - - -0.2419 0.8402 221125_WJC_METTL3_EV_vs_WT_F09.20778.20778.2 1.11 22-Mar K.GLTPSQIGVILR.D "sp|P62277|RS13_HUMAN,tr|J3KMX5|J3KMX5_HUMAN" 2 1252.7503 999 135669 20778 2 1252.747756 627.3824 40S ribosomal protein S13 OS=Homo sapiens OX=9606 GN=RPS13 PE=1 SV=2 9.75 3627.7 - 35830.7 - - - -2.0483 - 0.734 0.159 - 19 2 2 0 -0.0026 12 0 0 0 9.21E+06 0.00E+00 - - - -0.7336 1 221125_WJC_METTL3_EV_vs_WT_F09.20791.20791.4 1.53E-08 18/120 R.K[136.11]HAASDVDLEIESLLNQQSTK[136.11].E "sp|Q86U44|MTA70_HUMAN,tr|F5H6D8|F5H6D8_HUMAN,tr|H0YFV6|H0YFV6_HUMAN,tr|B4DTN4|B4DTN4_HUMAN" 4 2341.2096 0.01 135672 20791 4 2341.207638 586.3097 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 4.75 3629.8 - 212343 - - - -0.8461 - 3.782 0.522 - 284.6 1 2 0 -0.002 21 0 0 0 1.20E+05 1.48E+07 - - - 4.2088 0.9951 221125_WJC_METTL3_EV_vs_WT_F09.20849.20849.3 0.0333 Apr-52 K.K[136.11]GPGEVAGTVTGQK[136.11].R "sp|Q86U44|MTA70_HUMAN,tr|F5H6D8|F5H6D8_HUMAN,tr|H0YFV6|H0YFV6_HUMAN,tr|B4DTN4|B4DTN4_HUMAN" 4 1343.738 0 135688 20849 3 1343.737339 448.9199 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 8.59 3638.6 - 50538.4 - - - -0.4763 - 0.877 0.364 - 14.4 1 2 0 -0.0006 14 0 0 0 9.18E+03 2.61E+06 - - - 2.2493 1 221125_WJC_METTL3_EV_vs_WT_F09.20899.20899.3 5.54E-06 Nov-84 K.DHTPSQELALTQSVGGDSSADR[166.11].L "sp|Q86U44|MTA70_HUMAN,tr|H0YFV6|H0YFV6_HUMAN" 2 2280.0494 0 135703 20899 3 2280.043619 761.0237 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 4.22 3646.4 - 62145 - - - -2.521 - 2.286 0.61 - 110 1 2 0 -0.0057 22 0 0 0 8.17E+03 6.37E+06 - - - 7.2995 0.9997 221125_WJC_METTL3_EV_vs_WT_F09.20940.20940.3 0.00756 Sep-80 R.K[136.11]HAASDVDLEIESLLNQQSTK[136.11].E "sp|Q86U44|MTA70_HUMAN,tr|F5H6D8|F5H6D8_HUMAN,tr|H0YFV6|H0YFV6_HUMAN,tr|B4DTN4|B4DTN4_HUMAN" 4 2341.2096 0.001 135714 20940 3 2341.206184 781.4105 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 4.75 3652.9 - 89637.4 - - - -1.4672 - 1.977 0.39 - 73.1 1 2 0 -0.0034 21 0 0 0 0.00E+00 6.69E+06 - - - 4.5212 0.992 221125_WJC_METTL3_EV_vs_WT_F09.20972.20972.2 0.178 26-Apr K.LISWYDNEFGYSNR[166.11].V "sp|P04406|G3P_HUMAN,tr|E7EUT5|E7EUT5_HUMAN" 2 1772.8034 1.08 135719 20972 2 1772.801365 887.409 Glyceraldehyde-3-phosphate dehydrogenase OS=Homo sapiens OX=9606 GN=GAPDH PE=1 SV=3 4.37 3658.3 - 32852.4 - - - -1.131 - 0.87 0.304 - 40.1 1 2 0 -0.002 14 0 0 0 4.13E+06 3.82E+06 - - - 0.9362 0.9989 221125_WJC_METTL3_EV_vs_WT_F09.20980.20980.2 1.01E-05 26-Jun K.LISWYDNEFGYSNR.V "sp|P04406|G3P_HUMAN,tr|E7EUT5|E7EUT5_HUMAN" 2 1762.7951 1.08 135722 20980 2 1762.789182 882.4048 Glyceraldehyde-3-phosphate dehydrogenase OS=Homo sapiens OX=9606 GN=GAPDH PE=1 SV=3 4.37 3659.4 - 34466 - - - -3.3572 - 1.668 0.518 - 111.1 1 2 0 -0.0059 14 0 0 0 4.13E+06 3.82E+06 - - - 4.149 0.9576 221125_WJC_METTL3_EV_vs_WT_F09.20981.20981.2 2.06 18-Apr R.FEELC[160.03]ADLFR.G "sp|P34931|HS71L_HUMAN,tr|Q53FA3|Q53FA3_HUMAN" 2 1298.5965 999 135723 20981 2 1298.594926 650.3055 Heat shock 70 kDa protein 1-like OS=Homo sapiens OX=9606 GN=HSPA1L PE=1 SV=2 4.14 3659.6 - 10904.2 - - - -1.2298 - 0.973 0.12 - 41.7 1 2 0 -0.0016 10 0 0 0 4.59E+05 0.00E+00 - - - -0.1496 0.9954 221125_WJC_METTL3_EV_vs_WT_F09.20985.20985.2 0.0136 22-Jul K.DAGVIAGLNVLR[166.11].L "sp|P0DMV8|HS71A_HUMAN,sp|P34931|HS71L_HUMAN,sp|P0DMV9|HS71B_HUMAN,tr|Q53FA3|Q53FA3_HUMAN,tr|A0A0G2JIW1|A0A0G2JIW1_HUMAN" 5 1206.696 0.16 135725 20985 2 1206.693583 604.3553 Heat shock 70 kDa protein 1A OS=Homo sapiens OX=9606 GN=HSPA1A PE=1 SV=1 5.84 3660.1 - 26292 - - - -1.9955 - 1.387 0.249 - 171.5 1 2 0 -0.0024 12 0 0 0 7.11E+05 4.45E+06 - - - 1.7401 0.9999 221125_WJC_METTL3_EV_vs_WT_F09.21037.21037.4 0.000217 10/120 R.K[136.11]HAASDVDLEIESLLNQQSTK[136.11].E "sp|Q86U44|MTA70_HUMAN,tr|F5H6D8|F5H6D8_HUMAN,tr|H0YFV6|H0YFV6_HUMAN,tr|B4DTN4|B4DTN4_HUMAN" 4 2341.2096 0.01 135742 21037 4 2341.205558 586.3097 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 4.75 3668.1 - 140155 - - - -1.7346 - 2.3 0.417 - 61.5 1 2 0 -0.0041 21 0 0 0 5.41E+04 4.63E+06 - - - 3.1298 0.9992 221125_WJC_METTL3_EV_vs_WT_F09.21075.21075.3 0.00156 May-52 K.K[136.11]GPGEVAGTVTGQK[136.11].R "sp|Q86U44|MTA70_HUMAN,tr|F5H6D8|F5H6D8_HUMAN,tr|H0YFV6|H0YFV6_HUMAN,tr|B4DTN4|B4DTN4_HUMAN" 4 1343.738 0.001 135753 21075 3 1343.734946 448.9199 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 8.59 3673.9 - 61806.1 - - - -2.2571 - 1.187 0.454 - 36.8 1 2 0 -0.003 14 0 0 0 0.00E+00 3.29E+06 - - - 4.0564 0.9999 221125_WJC_METTL3_EV_vs_WT_F09.21110.21110.3 2.07E-05 Aug-84 K.DHTPSQELALTQSVGGDSSADR[166.11].L "sp|Q86U44|MTA70_HUMAN,tr|H0YFV6|H0YFV6_HUMAN" 2 2280.0494 0 135765 21110 3 2280.044533 761.0237 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 4.22 3679 - 53550.7 - - - -2.1201 - 1.894 0.549 - 44.9 1 2 0 -0.0048 22 0 0 0 1.14E+04 4.41E+06 - - - 6.1737 0.9999 221125_WJC_METTL3_EV_vs_WT_F09.21138.21138.3 0.000481 Sep-80 R.K[136.11]HAASDVDLEIESLLNQQSTK[136.11].E "sp|Q86U44|MTA70_HUMAN,tr|F5H6D8|F5H6D8_HUMAN,tr|H0YFV6|H0YFV6_HUMAN,tr|B4DTN4|B4DTN4_HUMAN" 4 2341.2096 0.001 135773 21138 3 2341.206208 781.4105 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 4.75 3683.4 - 69931.8 - - - -1.4569 - 2.124 0.476 - 75 1 2 0 -0.0034 21 0 0 0 0.00E+00 5.58E+06 - - - 5.652 0.9984 221125_WJC_METTL3_EV_vs_WT_F09.21190.21190.2 0.143 18-Mar K.NGFLLDGFPR.T "sp|P54819|KAD2_HUMAN,tr|A0A5F9ZHP2|A0A5F9ZHP2_HUMAN,tr|G3V213|G3V213_HUMAN,tr|F8VY04|F8VY04_HUMAN,tr|F8W1A4|F8W1A4_HUMAN,tr|A0A5K1VW67|A0A5K1VW67_HUMAN,tr|F8VZG5|F8VZG5_HUMAN" 7 1134.5822 0.38 135784 21190 2 1134.581874 568.2984 "Adenylate kinase 2, mitochondrial OS=Homo sapiens OX=9606 GN=AK2 PE=1 SV=2" 5.84 3691.8 - 49017.9 - - - -0.282 - 0.887 0.44 - 21.8 1 2 0 -0.0003 10 0 0 0 2.24E+06 5.91E+06 - - - 1.956 0.9979 221125_WJC_METTL3_EV_vs_WT_F09.21252.21252.2 0.0458 24-Apr R.TTNFAGILSQGLR[166.11].L "sp|P09874|PARP1_HUMAN,tr|A0A7I2V3E1|A0A7I2V3E1_HUMAN" 2 1386.7495 0.57 135799 21252 2 1386.748901 694.382 Poly [ADP-ribose] polymerase 1 OS=Homo sapiens OX=9606 GN=PARP1 PE=1 SV=4 9.41 3701.6 - 31538.1 - - - -0.4197 - 1.079 0.343 - 57.5 1 2 0 -0.0006 13 0 0 0 6.01E+05 1.05E+06 - - - 1.7694 1 221125_WJC_METTL3_EV_vs_WT_F09.21268.21268.3 1.16E-05 Aug-52 K.K[136.11]GPGEVAGTVTGQK[136.11].R "sp|Q86U44|MTA70_HUMAN,tr|F5H6D8|F5H6D8_HUMAN,tr|H0YFV6|H0YFV6_HUMAN,tr|B4DTN4|B4DTN4_HUMAN" 4 1343.738 0.001 135804 21268 3 1343.73614 448.9199 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 8.59 3704.2 - 51747.7 - - - -1.3686 - 1.632 0.628 - 89.8 1 2 0 -0.0018 14 0 0 0 0.00E+00 3.45E+06 - - - 6.8427 0.9997 221125_WJC_METTL3_EV_vs_WT_F09.21300.21300.3 0.00012 Aug-84 K.DHTPSQELALTQSVGGDSSADR[166.11].L "sp|Q86U44|MTA70_HUMAN,tr|H0YFV6|H0YFV6_HUMAN" 2 2280.0494 0 135813 21300 3 2280.041191 761.0237 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 4.22 3709.4 - 43414.3 - - - -3.5859 - 1.687 0.536 - 45.5 1 2 0 -0.0082 22 0 0 0 1.21E+04 4.00E+06 - - - 5.7534 0.9986 221125_WJC_METTL3_EV_vs_WT_F09.21333.21333.3 0.0439 May-80 R.K[136.11]HAASDVDLEIESLLNQQSTK[136.11].E "sp|Q86U44|MTA70_HUMAN,tr|F5H6D8|F5H6D8_HUMAN,tr|H0YFV6|H0YFV6_HUMAN,tr|B4DTN4|B4DTN4_HUMAN" 4 2341.2096 0.001 135820 21333 3 2341.205527 781.4105 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 4.75 3715.1 - 50383.8 - - - -1.7478 - 1.335 0.373 - 21 1 2 0 -0.0041 21 0 0 0 0.00E+00 4.63E+06 - - - 3.3901 0.979 221125_WJC_METTL3_EV_vs_WT_F09.21360.21360.3 0.0777 May-76 K.HAASDVDLEIESLLNQQSTK[136.11].E "sp|Q86U44|MTA70_HUMAN,tr|F5H6D8|F5H6D8_HUMAN,tr|H0YFV6|H0YFV6_HUMAN,tr|B4DTN4|B4DTN4_HUMAN" 4 2205.1005 0.02 135830 21360 3 2205.095225 736.0408 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 4.31 3719.3 - 38975.5 - - - -2.3722 - 1.366 0.231 - 25.4 1 2 0 -0.0052 20 0 0 0 1.41E+06 8.45E+07 - - - 1.8706 0.9995 221125_WJC_METTL3_EV_vs_WT_F09.21390.21390.3 0.0119 May-60 K.K[136.11]VSQEILELLNTTTAK[136.11].E "sp|Q86U44|MTA70_HUMAN,tr|H0YFV6|H0YFV6_HUMAN" 2 1803.0324 0 135839 21390 3 1803.028801 602.0181 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 6.14 3723.8 - 87631.5 - - - -2.0127 - 1.467 0.434 - 26.5 1 2 0 -0.0036 16 0 0 0 5.74E+04 3.32E+07 - - - 4.361 0.9103 221125_WJC_METTL3_EV_vs_WT_F09.21430.21430.2 0.0853 24-Mar K.ELAPYDENWFYTR.A "sp|P39019|RS19_HUMAN,tr|M0R140|M0R140_HUMAN,tr|M0R2L9|M0R2L9_HUMAN,tr|M0QYF7|M0QYF7_HUMAN" 4 1702.7627 1.65 135850 21430 2 1702.757535 852.3886 40S ribosomal protein S19 OS=Homo sapiens OX=9606 GN=RPS19 PE=1 SV=2 4.14 3730.1 - 46623.5 - - - -3.055 - 0.753 0.247 - 23.9 1 2 0 -0.0052 13 0 0 0 1.01E+06 6.11E+05 - - - 0.1356 0.9995 221125_WJC_METTL3_EV_vs_WT_F09.21433.21433.4 1.03E-05 10/120 R.K[136.11]HAASDVDLEIESLLNQQSTK[136.11].E "sp|Q86U44|MTA70_HUMAN,tr|F5H6D8|F5H6D8_HUMAN,tr|H0YFV6|H0YFV6_HUMAN,tr|B4DTN4|B4DTN4_HUMAN" 4 2341.2096 0.01 135851 21433 4 2341.19914 586.3097 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 4.75 3730.5 - 119008 - - - -4.4759 - 2.351 0.464 - 58.8 1 2 0 -0.0105 21 0 0 0 3.95E+04 7.76E+06 - - - 3.5444 0.9997 221125_WJC_METTL3_EV_vs_WT_F09.21459.21459.3 0.0102 May-52 K.K[136.11]GPGEVAGTVTGQK[136.11].R "sp|Q86U44|MTA70_HUMAN,tr|F5H6D8|F5H6D8_HUMAN,tr|H0YFV6|H0YFV6_HUMAN,tr|B4DTN4|B4DTN4_HUMAN" 4 1343.738 0.001 135858 21459 3 1343.735498 448.9199 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 8.59 3734.5 - 40285.4 - - - -1.8463 - 1.226 0.508 - 25.4 1 2 0 -0.0025 14 0 0 0 0.00E+00 6.73E+06 - - - 4.7445 1 221125_WJC_METTL3_EV_vs_WT_F09.21508.21508.3 1.24E-07 Oct-84 K.DHTPSQELALTQSVGGDSSADR[166.11].L "sp|Q86U44|MTA70_HUMAN,tr|H0YFV6|H0YFV6_HUMAN" 2 2280.0494 0.001 135872 21508 3 2280.04707 761.0237 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 4.22 3742.1 - 41719.7 - - - -1.0074 - 2.246 0.622 - 100.7 1 2 0 -0.0023 22 0 0 0 0.00E+00 2.13E+06 - - - 7.3924 0.9973 221125_WJC_METTL3_EV_vs_WT_F09.21557.21557.3 0.0146 Apr-80 R.K[136.11]HAASDVDLEIESLLNQQSTK[136.11].E "sp|Q86U44|MTA70_HUMAN,tr|F5H6D8|F5H6D8_HUMAN,tr|H0YFV6|H0YFV6_HUMAN,tr|B4DTN4|B4DTN4_HUMAN" 4 2341.2096 0.001 135891 21557 3 2341.206352 781.4105 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 4.75 3749.4 - 73330.2 - - - -1.3954 - 1.233 0.333 - 15.8 1 2 0 -0.0033 21 0 0 0 0.00E+00 3.03E+06 - - - 2.7539 0.9898 221125_WJC_METTL3_EV_vs_WT_F09.21565.21565.3 0.000511 Aug-76 K.HAASDVDLEIESLLNQQSTK[136.11].E "sp|Q86U44|MTA70_HUMAN,tr|F5H6D8|F5H6D8_HUMAN,tr|H0YFV6|H0YFV6_HUMAN,tr|B4DTN4|B4DTN4_HUMAN" 4 2205.1005 0.02 135894 21565 3 2206.095051 736.0408 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 4.31 3750.6 - 117712 - - - 451.0429 - 1.899 0.553 - 56 1 2 0 0.9946 20 0 0 0 1.41E+06 8.45E+07 - - - 5.9858 0.9997 221125_WJC_METTL3_EV_vs_WT_F09.21632.21632.4 0.00821 6/120 R.K[136.11]HAASDVDLEIESLLNQQSTK[136.11].E "sp|Q86U44|MTA70_HUMAN,tr|F5H6D8|F5H6D8_HUMAN,tr|H0YFV6|H0YFV6_HUMAN,tr|B4DTN4|B4DTN4_HUMAN" 4 2341.2096 0.01 135910 21632 4 2341.202666 586.3097 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 4.75 3760.9 - 66137.6 - - - -2.9698 - 1.336 0.438 - 17 1 2 0 -0.007 21 0 0 0 2.67E+04 2.33E+06 - - - 3.1322 0.9165 221125_WJC_METTL3_EV_vs_WT_F09.21665.21665.3 0.131 Apr-52 K.K[136.11]GPGEVAGTVTGQK[136.11].R "sp|Q86U44|MTA70_HUMAN,tr|F5H6D8|F5H6D8_HUMAN,tr|H0YFV6|H0YFV6_HUMAN,tr|B4DTN4|B4DTN4_HUMAN" 4 1343.738 0 135924 21665 3 1343.731881 448.9199 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 8.59 3765.7 - 21733 - - - -4.5381 - 1.125 0.291 - 17.8 2 2 0 -0.0061 14 0 0 0 5.80E+03 3.45E+06 - - - 1.9564 0.8751 221125_WJC_METTL3_EV_vs_WT_F09.21691.21691.4 8.88E-05 6/192 R.R[166.11]AEQDSTTVAAFASSLVSGLNSSASEPAK[136.11]EPAK[136.11].K "sp|Q86U44|MTA70_HUMAN,tr|F5H6D8|F5H6D8_HUMAN,tr|H0YFV6|H0YFV6_HUMAN,tr|B4DTN4|B4DTN4_HUMAN" 4 3331.6742 0.001 135934 21691 4 3332.660923 833.9258 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 4.87 3769.5 - 57158 - - - 296.1604 - 1.688 0.48 - 13.3 1 2 1 0.9867 33 0 0 0 0.00E+00 1.85E+06 - - - 3.2877 0.9989 221125_WJC_METTL3_EV_vs_WT_F09.21711.21711.3 0.00226 Jun-84 K.DHTPSQELALTQSVGGDSSADR[166.11].L "sp|Q86U44|MTA70_HUMAN,tr|H0YFV6|H0YFV6_HUMAN" 2 2280.0494 0.001 135937 21711 3 2280.04346 761.0237 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 4.22 3772.6 - 31404.8 - - - -2.5907 - 1.423 0.417 - 21.6 1 2 0 -0.0059 22 0 0 0 0.00E+00 2.46E+06 - - - 4.0239 0.9836 221125_WJC_METTL3_EV_vs_WT_F09.21783.21783.2 0.462 22-Apr K.ADTLTDEINFLR.A "sp|P48668|K2C6C_HUMAN,sp|P04259|K2C6B_HUMAN,sp|P02538|K2C6A_HUMAN" 3 1406.7042 11.45 135959 21783 2 1406.702337 704.3594 "Keratin, type II cytoskeletal 6C OS=Homo sapiens OX=9606 GN=KRT6C PE=1 SV=3" 4.03 3783.3 - 16351.2 - - - -1.2952 - 1.028 0.188 - 39.5 1 2 0 -0.0018 12 0 0 0 1.79E+06 1.56E+05 - - - 0.5017 1 221125_WJC_METTL3_EV_vs_WT_F09.21829.21829.4 4.07E-05 6/156 K.VLYDAEISQIHQSVTDTNVILSMDNSR.N sp|P35908|K22E_HUMAN 1 3047.487 16.06 135974 21829 4 3047.488342 762.879 "Keratin, type II cytoskeletal 2 epidermal OS=Homo sapiens OX=9606 GN=KRT2 PE=1 SV=2" 4.22 3790.6 - 68151.2 - - - 0.4469 - 1.282 0.565 - 16.4 1 2 0 0.0014 27 0 0 0 7.92E+05 4.93E+04 - - - 4.2211 1 221125_WJC_METTL3_EV_vs_WT_F09.21831.21831.3 0.000131 5/104 K.VLYDAEISQIHQSVTDTNVILSMDNSR.N sp|P35908|K22E_HUMAN 1 3047.487 999 135976 21831 3 3047.483273 1016.8363 "Keratin, type II cytoskeletal 2 epidermal OS=Homo sapiens OX=9606 GN=KRT2 PE=1 SV=2" 4.22 3790.9 - 67310.1 - - - -1.2164 - 1.667 0.575 - 20.1 1 2 0 -0.0037 27 0 0 0 2.01E+06 0.00E+00 - - - 6.1253 0.9841 221125_WJC_METTL3_EV_vs_WT_F09.21845.21845.4 0.126 6/120 R.K[136.11]HAASDVDLEIESLLNQQSTK[136.11].E "sp|Q86U44|MTA70_HUMAN,tr|F5H6D8|F5H6D8_HUMAN,tr|H0YFV6|H0YFV6_HUMAN,tr|B4DTN4|B4DTN4_HUMAN" 4 2341.2096 0 135980 21845 4 2341.205448 586.3097 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 4.75 3793.1 - 43479.8 - - - -1.7816 - 1.559 0.197 - 22.1 1 2 0 -0.0042 21 0 0 0 6.45E+03 4.03E+06 - - - 1.0864 0.9995 221125_WJC_METTL3_EV_vs_WT_F09.21863.21863.3 0.000266 Jul-52 K.K[136.11]GPGEVAGTVTGQK[136.11].R "sp|Q86U44|MTA70_HUMAN,tr|F5H6D8|F5H6D8_HUMAN,tr|H0YFV6|H0YFV6_HUMAN,tr|B4DTN4|B4DTN4_HUMAN" 4 1343.738 0 135984 21863 3 1343.73231 448.9199 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 8.59 3796.1 - 36652.1 - - - -4.2188 - 1.622 0.539 - 48.9 1 2 0 -0.0057 14 0 0 0 1.26E+04 2.80E+06 - - - 5.8331 1 221125_WJC_METTL3_EV_vs_WT_F09.21867.21867.4 1.74E-15 28/192 R.AEQDSTTVAAFASSLVSGLNSSASEPAK[136.11]EPAK[136.11]K[136.11].S "sp|Q86U44|MTA70_HUMAN,tr|F5H6D8|F5H6D8_HUMAN,tr|H0YFV6|H0YFV6_HUMAN,tr|B4DTN4|B4DTN4_HUMAN" 4 3301.674 0.01 135985 21867 4 3301.668176 826.4258 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 4.87 3796.7 - 682237 - - - -1.7624 - 4.99 0.725 - 385 1 2 1 -0.0058 33 0 0 0 2.19E+05 4.24E+07 - - - 6.0171 0.9995 221125_WJC_METTL3_EV_vs_WT_F09.21916.21916.3 0.0251 May-84 K.DHTPSQELALTQSVGGDSSADR[166.11].L "sp|Q86U44|MTA70_HUMAN,tr|H0YFV6|H0YFV6_HUMAN" 2 2280.0494 0 135998 21916 3 2280.046645 761.0237 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 4.22 3804.3 - 34176.2 - - - -1.1938 - 1.113 0.452 - 15.2 1 2 0 -0.0027 22 0 0 0 8.86E+03 3.54E+06 - - - 3.8324 0.9992 221125_WJC_METTL3_EV_vs_WT_F09.21947.21947.2 0.00043 28-Jun K.VSQEILELLNTTTAK[136.11].E "sp|Q86U44|MTA70_HUMAN,tr|H0YFV6|H0YFV6_HUMAN" 2 1666.9233 0.01 136006 21947 2 1666.919448 834.4689 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 4.53 3809.2 - 17240.9 - - - -2.291 - 1.729 0.425 - 83.6 1 2 0 -0.0038 15 0 0 0 1.01E+05 1.68E+07 - - - 3.525 0.9019 221125_WJC_METTL3_EV_vs_WT_F09.22004.22004.3 0.0148 May-80 R.K[136.11]HAASDVDLEIESLLNQQSTK[136.11].E "sp|Q86U44|MTA70_HUMAN,tr|F5H6D8|F5H6D8_HUMAN,tr|H0YFV6|H0YFV6_HUMAN,tr|B4DTN4|B4DTN4_HUMAN" 4 2341.2096 0.01 136016 22004 3 2342.204262 781.4105 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 4.75 3818.9 - 23587 - - - 424.8415 - 1.399 0.415 - 12.8 1 2 0 0.9946 21 0 0 0 2.30E+04 4.28E+06 - - - 3.6963 0.9314 221125_WJC_METTL3_EV_vs_WT_F09.22115.22115.3 0.156 Apr-84 K.DHTPSQELALTQSVGGDSSADR[166.11].L "sp|Q86U44|MTA70_HUMAN,tr|H0YFV6|H0YFV6_HUMAN" 2 2280.0494 0.01 136044 22115 3 2280.050844 761.0237 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 4.22 3837 - 31306.1 - - - 0.6478 - 0.937 0.205 - 11.1 1 2 0 0.0015 22 0 0 0 1.07E+04 9.62E+05 - - - 0.6709 1 221125_WJC_METTL3_EV_vs_WT_F09.22194.22194.3 3.99E-08 7/112 K.DIENQYETQITQIEHEVSSSGQEVQSSAK.E "sp|P35527|K1C9_HUMAN,tr|K7EQQ3|K7EQQ3_HUMAN" 2 3263.5066 999 136062 22194 3 3263.506648 1088.8428 "Keratin, type I cytoskeletal 9 OS=Homo sapiens OX=9606 GN=KRT9 PE=1 SV=3" 4.14 3850.5 - 56855.9 - - - 0.0181 - 2.199 0.551 - 33.2 1 2 0 0.0001 29 0 0 0 8.49E+06 0.00E+00 - - - 6.496 0.9991 221125_WJC_METTL3_EV_vs_WT_F09.22201.22201.3 0.00328 Jul-80 R.K[136.11]HAASDVDLEIESLLNQQSTK[136.11].E "sp|Q86U44|MTA70_HUMAN,tr|F5H6D8|F5H6D8_HUMAN,tr|H0YFV6|H0YFV6_HUMAN,tr|B4DTN4|B4DTN4_HUMAN" 4 2341.2096 0.001 136063 22201 3 2341.206616 781.4105 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 4.75 3851.7 - 94558.4 - - - -1.2827 - 1.736 0.326 - 37.4 1 2 0 -0.003 21 0 0 0 0.00E+00 3.34E+06 - - - 3.4961 0.9996 221125_WJC_METTL3_EV_vs_WT_F09.22214.22214.4 0.0873 4/168 K.DIENQYETQITQIEHEVSSSGQEVQSSAK.E "sp|P35527|K1C9_HUMAN,tr|K7EQQ3|K7EQQ3_HUMAN" 2 3263.5066 999 136066 22214 4 3263.504892 816.8839 "Keratin, type I cytoskeletal 9 OS=Homo sapiens OX=9606 GN=KRT9 PE=1 SV=3" 4.14 3854 - 27117.8 - - - -0.52 - 0.889 0.382 - 7.2 1 2 0 -0.0017 29 0 0 0 2.04E+06 0.00E+00 - - - 2.5142 0.9998 221125_WJC_METTL3_EV_vs_WT_F09.22237.22237.4 1.77E-05 11/120 R.K[136.11]HAASDVDLEIESLLNQQSTK[136.11].E "sp|Q86U44|MTA70_HUMAN,tr|F5H6D8|F5H6D8_HUMAN,tr|H0YFV6|H0YFV6_HUMAN,tr|B4DTN4|B4DTN4_HUMAN" 4 2341.2096 0 136071 22237 4 2341.207233 586.3097 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 4.75 3857.7 - 42377.1 - - - -1.0191 - 2.396 0.375 - 69.5 1 2 0 -0.0024 21 0 0 0 5.40E+03 3.89E+06 - - - 2.7783 0.9993 221125_WJC_METTL3_EV_vs_WT_F09.22283.22283.2 0.0262 18-May K.LLEPVLLLGK.E "sp|P62249|RS16_HUMAN,tr|M0R210|M0R210_HUMAN,tr|M0R3H0|M0R3H0_HUMAN,tr|M0QX76|M0QX76_HUMAN,tr|M0R1M5|M0R1M5_HUMAN,tr|Q6IPX4|Q6IPX4_HUMAN" 6 1093.7111 0.92 136078 22283 2 1093.710521 547.8628 40S ribosomal protein S16 OS=Homo sapiens OX=9606 GN=RPS16 PE=1 SV=2 6 3866 - 38629.1 - - - -0.5138 - 1.154 0.451 - 76.9 1 2 0 -0.0006 10 0 0 0 2.54E+06 2.76E+06 - - - 2.7717 0.9987 221125_WJC_METTL3_EV_vs_WT_F09.22292.22292.2 0.328 18-Jun K.LLEPVLLLGK[136.11].E "sp|P62249|RS16_HUMAN,tr|M0R210|M0R210_HUMAN,tr|M0R3H0|M0R3H0_HUMAN,tr|M0QX76|M0QX76_HUMAN,tr|M0R1M5|M0R1M5_HUMAN,tr|Q6IPX4|Q6IPX4_HUMAN" 6 1101.7253 0.92 136081 22292 2 1101.725291 551.8699 40S ribosomal protein S16 OS=Homo sapiens OX=9606 GN=RPS16 PE=1 SV=2 6 3867.3 - 85796.5 - - - 0.0073 - 1.395 0.296 - 111.8 1 2 0 0 10 0 0 0 2.54E+06 2.76E+06 - - - 2.1565 0.9647 221125_WJC_METTL3_EV_vs_WT_F09.22316.22316.3 0.149 May-52 K.K[136.11]GPGEVAGTVTGQK[136.11].R "sp|Q86U44|MTA70_HUMAN,tr|F5H6D8|F5H6D8_HUMAN,tr|H0YFV6|H0YFV6_HUMAN,tr|B4DTN4|B4DTN4_HUMAN" 4 1343.738 0.001 136084 22316 3 1343.735914 448.9199 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 8.59 3871.7 - 29015.5 - - - -1.5368 - 0.985 0.244 - 24.1 1 2 0 -0.0021 14 0 0 0 0.00E+00 8.19E+05 - - - 1.2196 0.9995 221125_WJC_METTL3_EV_vs_WT_F09.22376.22376.3 8.68E-07 14/80 R.K[136.11]HAASDVDLEIESLLNQQSTK[136.11].E "sp|Q86U44|MTA70_HUMAN,tr|F5H6D8|F5H6D8_HUMAN,tr|H0YFV6|H0YFV6_HUMAN,tr|B4DTN4|B4DTN4_HUMAN" 4 2341.2096 0 136097 22376 3 2342.210519 781.4105 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 4.75 3882 - 50291.1 - - - 427.514 - 2.819 0.579 - 221.5 1 2 0 1.0009 21 0 0 0 7.89E+03 1.38E+07 - - - 7.2027 0.9997 221125_WJC_METTL3_EV_vs_WT_F09.22412.22412.4 0.00416 7/120 R.K[136.11]HAASDVDLEIESLLNQQSTK[136.11].E "sp|Q86U44|MTA70_HUMAN,tr|F5H6D8|F5H6D8_HUMAN,tr|H0YFV6|H0YFV6_HUMAN,tr|B4DTN4|B4DTN4_HUMAN" 4 2341.2096 0 136105 22412 4 2341.206373 586.3097 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 4.75 3888.1 - 132691 - - - -1.3865 - 1.629 0.361 - 33 1 2 0 -0.0032 21 0 0 0 2.43E+04 9.31E+06 - - - 2.5286 0.9959 221125_WJC_METTL3_EV_vs_WT_F09.22485.22485.3 0.00409 May-84 K.DHTPSQELALTQSVGGDSSADR[166.11].L "sp|Q86U44|MTA70_HUMAN,tr|H0YFV6|H0YFV6_HUMAN" 2 2280.0494 0 136122 22485 3 2280.039899 761.0237 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 4.22 3900.1 - 32743.1 - - - -4.1525 - 1.127 0.452 - 13.7 1 2 0 -0.0095 22 0 0 0 7.34E+03 3.78E+06 - - - 3.8602 0.995 221125_WJC_METTL3_EV_vs_WT_F09.22564.22564.4 0.0167 5/168 R.R[166.11]AEQDSTTVAAFASSLVSGLNSSASEPAK[136.11].E "sp|Q86U44|MTA70_HUMAN,tr|F5H6D8|F5H6D8_HUMAN,tr|H0YFV6|H0YFV6_HUMAN,tr|B4DTN4|B4DTN4_HUMAN" 4 2898.4326 0.001 136135 22564 4 2898.422315 725.6154 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 4.68 3913.6 - 34139.6 - - - -3.5416 - 1.135 0.316 - 8.2 1 2 0 -0.0103 29 0 0 0 0.00E+00 2.71E+05 - - - 2.0126 1 221125_WJC_METTL3_EV_vs_WT_F09.22578.22578.3 2.67E-08 17/80 R.K[136.11]HAASDVDLEIESLLNQQSTK[136.11].E "sp|Q86U44|MTA70_HUMAN,tr|F5H6D8|F5H6D8_HUMAN,tr|H0YFV6|H0YFV6_HUMAN,tr|B4DTN4|B4DTN4_HUMAN" 4 2341.2096 0 136141 22578 3 2341.203085 781.4105 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 4.75 3915.5 - 189933 - - - -2.7909 - 3.605 0.604 - 396.6 1 2 0 -0.0065 21 0 0 0 1.27E+04 1.92E+07 - - - 8.3465 0.9898 221125_WJC_METTL3_EV_vs_WT_F09.22583.22583.3 3.99E-05 7/112 R.R[166.11]AEQDSTTVAAFASSLVSGLNSSASEPAK[136.11].E "sp|Q86U44|MTA70_HUMAN,tr|F5H6D8|F5H6D8_HUMAN,tr|H0YFV6|H0YFV6_HUMAN,tr|B4DTN4|B4DTN4_HUMAN" 4 2898.4326 0.001 136142 22583 3 2899.425958 967.1515 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 4.68 3916.4 - 61432.5 - - - 342.7294 - 2.049 0.507 - 25.2 1 2 0 0.9934 29 0 0 0 0.00E+00 1.04E+07 - - - 5.5677 0.9977 221125_WJC_METTL3_EV_vs_WT_F09.22621.22621.4 7.18E-11 23/120 R.K[136.11]HAASDVDLEIESLLNQQSTK[136.11].E "sp|Q86U44|MTA70_HUMAN,tr|F5H6D8|F5H6D8_HUMAN,tr|H0YFV6|H0YFV6_HUMAN,tr|B4DTN4|B4DTN4_HUMAN" 4 2341.2096 0.01 136155 22621 4 2342.204966 586.3097 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 4.75 3922 - 105194 - - - 425.1422 - 4.393 0.594 - 412 1 2 0 0.9953 21 0 0 0 2.49E+05 3.05E+07 - - - 4.6098 0.7699 221125_WJC_METTL3_EV_vs_WT_F09.22630.22630.4 0.000573 5/186 R.AEQDSTTVAAFASSLVSGLNSSASEPAK[136.11]EPAK[136.11].K "sp|Q86U44|MTA70_HUMAN,tr|F5H6D8|F5H6D8_HUMAN,tr|H0YFV6|H0YFV6_HUMAN,tr|B4DTN4|B4DTN4_HUMAN" 4 3165.5648 0.04 136157 22630 4 3166.553668 792.3985 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 4.41 3923.5 - 62338.5 - - - 312.3727 - 1.291 0.423 - 12.6 1 2 1 0.9888 32 0 0 0 1.11E+05 2.55E+06 - - - 2.711 1 221125_WJC_METTL3_EV_vs_WT_F09.22746.22746.4 6.97E-07 16/114 K.R[166.11]GLLQDDAHPTLVTYADHSK[136.11].L "sp|Q86U44|MTA70_HUMAN,tr|F5H6D8|F5H6D8_HUMAN,tr|H0YFV6|H0YFV6_HUMAN,tr|B4DTN4|B4DTN4_HUMAN" 4 2254.1461 0.01 136187 22746 4 2254.144844 564.5438 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 5.99 3942 - 112801 - - - -0.5638 - 2.973 0.555 - 247.3 1 2 0 -0.0013 20 0 0 0 7.73E+03 1.15E+06 - - - 4.4206 1 221125_WJC_METTL3_EV_vs_WT_F09.22749.22749.3 0.000227 13/56 R.STSHK[136.11]PDEIYGMIER[166.11].L sp|Q86U44|MTA70_HUMAN 1 1779.8581 1.11 136188 22749 3 1779.858058 594.2933 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 5.42 3942.4 - 107145 - - - 0.0022 - 2.465 0.546 - 212.4 1 2 0 0 15 0 0 0 1.91E+06 1.71E+06 - - - 6.9815 1 221125_WJC_METTL3_EV_vs_WT_F09.22756.22756.4 2.92E-07 15/102 R.SPSELFAQHIVTIVHHVK.E "sp|Q9Y2W1|TR150_HUMAN,tr|A0A3B3ITZ9|A0A3B3ITZ9_HUMAN" 2 2041.1109 3.25 136193 22756 4 2041.10803 511.285 Thyroid hormone receptor-associated protein 3 OS=Homo sapiens OX=9606 GN=THRAP3 PE=1 SV=2 6.78 3943.3 - 70586.3 - - - -1.4036 - 2.979 0.5 - 163.9 1 2 0 -0.0029 18 0 0 0 6.91E+06 2.13E+06 - - - 3.9511 1 221125_WJC_METTL3_EV_vs_WT_F09.22760.22760.4 5.15E-10 21/102 R.SPSELFAQHIVTIVHHVK[136.11].E "sp|Q9Y2W1|TR150_HUMAN,tr|A0A3B3ITZ9|A0A3B3ITZ9_HUMAN" 2 2049.1251 3.25 136195 22760 4 2049.125713 513.2886 Thyroid hormone receptor-associated protein 3 OS=Homo sapiens OX=9606 GN=THRAP3 PE=1 SV=2 6.78 3943.8 - 312587 - - - 0.3016 - 3.53 0.624 - 354.6 1 2 0 0.0006 18 0 0 0 6.90E+06 2.12E+06 - - - 5.0892 0.9999 221125_WJC_METTL3_EV_vs_WT_F09.22767.22767.3 1.58E-07 16/68 R.SPSELFAQHIVTIVHHVK.E "sp|Q9Y2W1|TR150_HUMAN,tr|A0A3B3ITZ9|A0A3B3ITZ9_HUMAN" 2 2041.1109 3.59 136200 22767 3 2041.102399 681.3776 Thyroid hormone receptor-associated protein 3 OS=Homo sapiens OX=9606 GN=THRAP3 PE=1 SV=2 6.78 3944.7 - 211767 - - - -4.1624 - 2.789 0.563 - 252 1 2 0 -0.0085 18 0 0 0 1.19E+06 3.30E+05 - - - 7.3686 0.9999 221125_WJC_METTL3_EV_vs_WT_F09.22778.22778.3 1.71E-06 15/80 R.K[136.11]HAASDVDLEIESLLNQQSTK[136.11].E "sp|Q86U44|MTA70_HUMAN,tr|F5H6D8|F5H6D8_HUMAN,tr|H0YFV6|H0YFV6_HUMAN,tr|B4DTN4|B4DTN4_HUMAN" 4 2341.2096 0.001 136207 22778 3 2341.200716 781.4105 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 4.75 3946.2 - 173131 - - - -3.8027 - 3.181 0.559 - 292.9 1 2 0 -0.0089 21 0 0 0 0.00E+00 5.55E+06 - - - 7.5442 0.9989 221125_WJC_METTL3_EV_vs_WT_F09.22783.22783.3 3.48E-05 Aug-48 R.KIEEIKDFLLTAR.R "sp|P63173|RL38_HUMAN,tr|J3KT73|J3KT73_HUMAN,tr|J3QL01|J3QL01_HUMAN,tr|J3KSP2|J3KSP2_HUMAN" 4 1574.9032 0.7 136209 22783 3 1574.897291 525.975 60S ribosomal protein L38 OS=Homo sapiens OX=9606 GN=RPL38 PE=1 SV=2 6.18 3946.9 - 64295 - - - -3.7482 - 1.811 0.547 - 94.1 1 2 1 -0.0059 13 0 0 0 2.80E+05 3.99E+05 - - - 6.2471 0.8034 221125_WJC_METTL3_EV_vs_WT_F09.22789.22789.3 0.0132 Aug-68 R.K[136.11]IELFGR[166.11]PHNVQPNWITL.G sp|Q86U44|MTA70_HUMAN 1 2179.2021 0.1 136212 22789 3 2179.193456 727.408 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 8.75 3947.6 - 176012 - - - -3.9726 - 1.646 0.398 - 73.8 1 1 0 -0.0087 18 0 0 0 2.16E+05 2.26E+06 - - - 4.2158 0.7973 221125_WJC_METTL3_EV_vs_WT_F09.22795.22795.4 8.86E-05 18/102 R.K[136.11]IELFGR[166.11]PHNVQPNWITL.G sp|Q86U44|MTA70_HUMAN 1 2179.2021 0.04 136216 22795 4 2179.187333 545.8078 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 8.75 3948.4 - 1.16E+06 - - - -6.7823 - 2.973 0.47 - 142.9 1 1 0 -0.0148 18 0 0 0 1.57E+05 4.03E+06 - - - 3.686 0.9978 221125_WJC_METTL3_EV_vs_WT_F09.22799.22799.4 2.53E-08 25/150 R.SFGTEDRPTDRPIPPRDEVFEYIIFR.G "sp|Q8ND56|LS14A_HUMAN,tr|I3L4Q1|I3L4Q1_HUMAN,tr|A0A140TA76|A0A140TA76_HUMAN,tr|K7EMZ9|K7EMZ9_HUMAN" 4 3151.5727 1.34 136217 22799 4 3151.552353 788.9005 Protein LSM14 homolog A OS=Homo sapiens OX=9606 GN=LSM14A PE=1 SV=3 4.59 3949 - 1.38E+06 - - - -6.4558 - 3.046 0.598 - 97.7 1 2 1 -0.0203 26 0 0 0 2.09E+07 1.56E+07 - - - 4.7767 1 221125_WJC_METTL3_EV_vs_WT_F09.22826.22826.3 2.82E-12 17/60 K.K[136.11]VSQEILELLNTTTAK[136.11].E "sp|Q86U44|MTA70_HUMAN,tr|H0YFV6|H0YFV6_HUMAN" 2 1803.0324 0 136226 22826 3 1803.019001 602.0181 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 6.14 3952.7 - 1.29E+06 - - - -7.448 - 3.641 0.676 - 512.1 1 2 0 -0.0134 16 0 0 0 6.19E+04 1.41E+07 - - - 9.3888 0.9162 221125_WJC_METTL3_EV_vs_WT_F09.22838.22838.4 6.08E-12 19/174 F.GR[166.11]PHNVQPNWITLGNQLDGIHLLDPDVVAR[166.11].F sp|Q86U44|MTA70_HUMAN 1 3363.7703 0.12 136229 22838 4 3363.748906 841.9499 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 5.99 3954.5 - 424700 - - - -6.3693 - 3.616 0.54 - 121.2 1 1 0 -0.0214 30 0 0 0 1.29E+05 1.11E+06 - - - 4.3136 0.9996 221125_WJC_METTL3_EV_vs_WT_F09.22839.22839.4 5.97E-09 12/102 K.STSESFIQHIVSLVHHVK[136.11].E "sp|Q9NYF8|BCLF1_HUMAN,tr|E9PKI6|E9PKI6_HUMAN,tr|A0A1W2PQ43|A0A1W2PQ43_HUMAN,tr|E9PK91|E9PK91_HUMAN,tr|E9PJA7|E9PJA7_HUMAN,tr|E9PK09|E9PK09_HUMAN,tr|E9PQN2|E9PQN2_HUMAN" 7 2055.0993 2.08 136230 22839 4 2055.086999 514.7821 Bcl-2-associated transcription factor 1 OS=Homo sapiens OX=9606 GN=BCLAF1 PE=1 SV=2 6.78 3954.7 - 359668 - - - -5.9729 - 2.728 0.617 - 94.4 1 2 0 -0.0123 18 0 0 0 9.99E+06 4.80E+06 - - - 4.9367 0.9998 221125_WJC_METTL3_EV_vs_WT_F09.22843.22843.4 3.80E-09 16/102 K.STSESFIQHIVSLVHHVK.E "sp|Q9NYF8|BCLF1_HUMAN,tr|E9PKI6|E9PKI6_HUMAN,tr|A0A1W2PQ43|A0A1W2PQ43_HUMAN,tr|E9PK91|E9PK91_HUMAN,tr|E9PJA7|E9PJA7_HUMAN,tr|E9PK09|E9PK09_HUMAN,tr|E9PQN2|E9PQN2_HUMAN" 7 2047.0851 2.08 136232 22843 4 2047.075132 512.7785 Bcl-2-associated transcription factor 1 OS=Homo sapiens OX=9606 GN=BCLAF1 PE=1 SV=2 6.78 3955.2 - 1.56E+06 - - - -4.8567 - 2.893 0.589 - 153.2 1 2 0 -0.0099 18 0 0 0 9.99E+06 4.80E+06 - - - 4.7138 1 221125_WJC_METTL3_EV_vs_WT_F09.22846.22846.4 7.94E-15 24/192 R.AEQDSTTVAAFASSLVSGLNSSASEPAK[136.11]EPAK[136.11]K[136.11].S "sp|Q86U44|MTA70_HUMAN,tr|F5H6D8|F5H6D8_HUMAN,tr|H0YFV6|H0YFV6_HUMAN,tr|B4DTN4|B4DTN4_HUMAN" 4 3301.674 0.16 136233 22846 4 3302.660296 826.4258 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 4.87 3955.6 - 484890 - - - 298.7276 - 4.251 0.723 - 252.6 1 2 1 0.9863 33 0 0 0 2.75E+06 1.76E+07 - - - 5.68 0.9999 221125_WJC_METTL3_EV_vs_WT_F09.22847.22847.3 1.79E-07 16/68 K.STSESFIQHIVSLVHHVK.E "sp|Q9NYF8|BCLF1_HUMAN,tr|E9PKI6|E9PKI6_HUMAN,tr|A0A1W2PQ43|A0A1W2PQ43_HUMAN,tr|E9PK91|E9PK91_HUMAN,tr|E9PJA7|E9PJA7_HUMAN,tr|E9PK09|E9PK09_HUMAN,tr|E9PQN2|E9PQN2_HUMAN" 7 2047.0851 3.77 136234 22847 3 2047.077451 683.369 Bcl-2-associated transcription factor 1 OS=Homo sapiens OX=9606 GN=BCLAF1 PE=1 SV=2 6.78 3955.7 - 377788 - - - -3.7238 - 3.363 0.605 - 379.6 1 2 0 -0.0076 18 0 0 0 3.81E+06 1.01E+06 - - - 8.3031 0.9906 221125_WJC_METTL3_EV_vs_WT_F09.22856.22856.4 1.07E-05 Nov-96 T.RTHNLEPYFESFINNLR.R sp|P04264|K2C1_HUMAN 1 2149.0705 36.76 136237 22856 4 2149.064897 538.2749 "Keratin, type II cytoskeletal 1 OS=Homo sapiens OX=9606 GN=KRT1 PE=1 SV=6" 6.76 3957 - 106217 - - - -2.6011 - 2.221 0.507 - 96.8 1 1 0 -0.0056 17 0 0 0 2.17E+06 5.91E+04 - - - 3.9144 0.9112 221125_WJC_METTL3_EV_vs_WT_F09.22876.22876.3 0.00734 Jul-64 R.THNLEPYFESFINNLRR.R sp|P04264|K2C1_HUMAN 1 2149.0705 14.95 136245 22876 3 2149.05776 717.3641 "Keratin, type II cytoskeletal 1 OS=Homo sapiens OX=9606 GN=KRT1 PE=1 SV=6" 6.42 3959.6 - 92218 - - - -5.9221 - 1.437 0.276 - 60.2 1 2 0 -0.0127 17 0 0 0 1.76E+06 1.18E+05 - - - 2.5295 0.9996 221125_WJC_METTL3_EV_vs_WT_F09.22884.22884.3 1.08E-06 Nov-56 R.HFYWYLTNEGIQYLR[166.11].D "sp|P46783|RS10_HUMAN,tr|A0A2R8Y6L3|A0A2R8Y6L3_HUMAN,tr|F6U211|F6U211_HUMAN,tr|A0A1W2PQS6|A0A1W2PQS6_HUMAN,tr|A0A2R8YFH6|A0A2R8YFH6_HUMAN,tr|A0A2R8Y7H1|A0A2R8Y7H1_HUMAN,tr|S4R435|S4R435_HUMAN" 7 2011.982 1.55 136248 22884 3 2011.970823 671.6679 40S ribosomal protein S10 OS=Homo sapiens OX=9606 GN=RPS10 PE=1 SV=1 6.75 3960.8 - 235045 - - - -5.5567 - 2.535 0.584 - 197.7 1 2 0 -0.0112 15 0 0 0 2.43E+06 1.57E+06 - - - 7.4751 0.9788 221125_WJC_METTL3_EV_vs_WT_F09.22915.22915.3 6.99E-06 Nov-84 K.DHTPSQELALTQSVGGDSSADR[166.11].L "sp|Q86U44|MTA70_HUMAN,tr|H0YFV6|H0YFV6_HUMAN" 2 2280.0494 0.01 136256 22915 3 2281.039121 761.0237 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 4.22 3965.2 - 64715.9 - - - 434.0932 - 2.556 0.568 - 113.4 1 2 0 0.9898 22 0 0 0 4.25E+04 3.05E+06 - - - 6.8234 0.9988 221125_WJC_METTL3_EV_vs_WT_F09.22919.22919.2 0.0725 22-Aug R.NLDLDSIIAEVK.A "sp|P48668|K2C6C_HUMAN,sp|P04259|K2C6B_HUMAN,sp|P13647|K2C5_HUMAN,sp|P35908|K22E_HUMAN,sp|O95678|K2C75_HUMAN,sp|Q5XKE5|K2C79_HUMAN,sp|P02538|K2C6A_HUMAN,tr|H0YI76|H0YI76_HUMAN,tr|H0YIN9|H0YIN9_HUMAN" 9 1328.7187 68.04 136258 22919 2 1328.714818 665.3666 "Keratin, type II cytoskeletal 6C OS=Homo sapiens OX=9606 GN=KRT6C PE=1 SV=3" 4.03 3965.8 - 82993.7 - - - -2.957 - 1.961 0.385 - 167.8 1 2 0 -0.0039 12 0 0 0 1.01E+06 1.49E+04 - - - 3.6553 0.9991 221125_WJC_METTL3_EV_vs_WT_F09.22926.22926.2 0.00553 22-Sep R.SLDLDSIIAEVK.A sp|P04264|K2C1_HUMAN 1 1301.7078 999 136263 22926 2 1301.703586 651.8612 "Keratin, type II cytoskeletal 1 OS=Homo sapiens OX=9606 GN=KRT1 PE=1 SV=6" 4.03 3966.6 - 91155.5 - - - -3.2742 - 2.284 0.427 - 177.8 1 2 0 -0.0043 12 0 0 0 1.08E+06 0.00E+00 - - - 4.3666 0.9638 221125_WJC_METTL3_EV_vs_WT_F09.22944.22944.3 0.00162 Aug-52 K.K[136.11]GPGEVAGTVTGQK[136.11].R "sp|Q86U44|MTA70_HUMAN,tr|F5H6D8|F5H6D8_HUMAN,tr|H0YFV6|H0YFV6_HUMAN,tr|B4DTN4|B4DTN4_HUMAN" 4 1343.738 0.001 136271 22944 3 1343.725767 448.9199 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 8.59 3969.1 - 48933.5 - - - -9.0881 - 1.475 0.424 - 63.8 1 2 0 -0.0122 14 0 0 0 0.00E+00 6.45E+06 - - - 4.2967 1 221125_WJC_METTL3_EV_vs_WT_F09.23030.23030.3 1.10E-13 15/60 R.THNLEPYFESFINNLR.R sp|P04264|K2C1_HUMAN 1 1992.9694 416.74 136296 23030 3 1992.960507 665.3304 "Keratin, type II cytoskeletal 1 OS=Homo sapiens OX=9606 GN=KRT1 PE=1 SV=6" 5.37 3982.1 - 125369 - - - -4.4501 - 3.239 0.694 - 492.4 1 2 0 -0.0089 16 0 0 0 7.97E+06 1.91E+04 - - - 9.2905 1 221125_WJC_METTL3_EV_vs_WT_F09.23036.23036.3 0.000105 20/84 R.KPLVIIAEDVDGEALSTLVLNR.L "sp|P10809|CH60_HUMAN,tr|A0A7I2V2X6|A0A7I2V2X6_HUMAN,tr|A0A7I2YQK6|A0A7I2YQK6_HUMAN,tr|A0A7I2V599|A0A7I2V599_HUMAN,tr|A0A7I2YQ71|A0A7I2YQ71_HUMAN,tr|A0A7I2V5M1|A0A7I2V5M1_HUMAN,tr|A0A7I2V5K3|A0A7I2V5K3_HUMAN" 7 2364.3264 0.72 136300 23036 3 2364.318867 789.1161 "60 kDa heat shock protein, mitochondrial OS=Homo sapiens OX=9606 GN=HSPD1 PE=1 SV=2" 4.32 3982.9 - 216560 - - - -3.1975 - 4.399 0.559 - 432.9 1 2 0 -0.0076 22 0 0 0 1.23E+07 1.70E+07 - - - 8.2823 1 221125_WJC_METTL3_EV_vs_WT_F09.23037.23037.3 1.49E-09 22/84 R.K[136.11]PLVIIAEDVDGEALSTLVLNR[166.11].L "sp|P10809|CH60_HUMAN,tr|A0A7I2V2X6|A0A7I2V2X6_HUMAN,tr|A0A7I2YQK6|A0A7I2YQK6_HUMAN,tr|A0A7I2V599|A0A7I2V599_HUMAN,tr|A0A7I2YQ71|A0A7I2YQ71_HUMAN,tr|A0A7I2V5M1|A0A7I2V5M1_HUMAN,tr|A0A7I2V5K3|A0A7I2V5K3_HUMAN" 7 2382.3489 1.36 136301 23037 3 2382.339561 795.1236 "60 kDa heat shock protein, mitochondrial OS=Homo sapiens OX=9606 GN=HSPD1 PE=1 SV=2" 4.32 3983 - 204894 - - - -3.9188 - 4.572 0.703 - 574.8 1 2 0 -0.0093 22 0 0 0 1.22E+07 8.94E+06 - - - 9.9787 0.9999 221125_WJC_METTL3_EV_vs_WT_F09.23047.23047.4 1.43E-07 12/126 R.KPLVIIAEDVDGEALSTLVLNR.L "sp|P10809|CH60_HUMAN,tr|A0A7I2V2X6|A0A7I2V2X6_HUMAN,tr|A0A7I2YQK6|A0A7I2YQK6_HUMAN,tr|A0A7I2V599|A0A7I2V599_HUMAN,tr|A0A7I2YQ71|A0A7I2YQ71_HUMAN,tr|A0A7I2V5M1|A0A7I2V5M1_HUMAN,tr|A0A7I2V5K3|A0A7I2V5K3_HUMAN" 7 2364.3264 1.27 136305 23047 4 2364.318282 592.0889 "60 kDa heat shock protein, mitochondrial OS=Homo sapiens OX=9606 GN=HSPD1 PE=1 SV=2" 4.32 3984.4 - 142109 - - - -3.445 - 2.596 0.562 - 133.9 1 2 0 -0.0081 22 0 0 0 1.39E+06 1.10E+06 - - - 4.4275 0.9177 221125_WJC_METTL3_EV_vs_WT_F09.23084.23084.3 1.03E-06 15/80 N.WITLGNQLDGIHLLDPDVVAR[166.11].F sp|Q86U44|MTA70_HUMAN 1 2354.2622 0 136319 23084 3 2354.249782 785.7613 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 4.41 3989.6 - 253603 - - - -5.2747 - 2.897 0.446 - 150.3 1 1 0 -0.0124 21 0 0 0 4.72E+04 1.20E+07 - - - 6.0591 0.9998 221125_WJC_METTL3_EV_vs_WT_F09.23129.23129.3 3.21E-09 Nov-84 K.DHTPSQELALTQSVGGDSSADR[166.11].L "sp|Q86U44|MTA70_HUMAN,tr|H0YFV6|H0YFV6_HUMAN" 2 2280.0494 0 136329 23129 3 2280.038185 761.0237 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 4.22 3996.4 - 110346 - - - -4.9043 - 2.523 0.62 - 103.7 1 2 0 -0.0112 22 0 0 0 2.10E+04 5.05E+06 - - - 7.6434 0.9486 221125_WJC_METTL3_EV_vs_WT_F09.23130.23130.3 0.0401 4/100 R.EIQLWFQSSELVSWADGGQHSSIHPA.- "sp|O00746|NDKM_HUMAN,tr|Q4TT34|Q4TT34_HUMAN,tr|A0A087WVT9|A0A087WVT9_HUMAN" 3 2908.378 - 136330 23130 3 2908.363392 970.4666 "Nucleoside diphosphate kinase, mitochondrial OS=Homo sapiens OX=9606 GN=NME4 PE=1 SV=1" 4.63 3996.6 - 45447.4 - - - -5.03 - 1.316 0.319 - 10.2 3 2 0 -0.0146 26 0 0 0 - - - - - 2.5034 1 221125_WJC_METTL3_EV_vs_WT_F09.23173.23173.4 3.05E-10 10/210 K.TC[160.03]NC[160.03]ETEDYGEK[136.11]FDENDVITC[160.03]FANFESDEVELSYAK[136.11].N "sp|Q00839|HNRPU_HUMAN,tr|A0A1W2PQL0|A0A1W2PQL0_HUMAN,tr|A0A1W2PPL4|A0A1W2PPL4_HUMAN,tr|A0A1W2PQ74|A0A1W2PQ74_HUMAN,tr|Q5RI18|Q5RI18_HUMAN,tr|A0A1W2PP35|A0A1W2PP35_HUMAN,tr|A0A1W2PPS1|A0A1W2PPS1_HUMAN,tr|A0A1W2PRZ7|A0A1W2PRZ7_HUMAN,tr|A0A1W2PPH7|A0A1W2PPH7_HUMAN,tr|A0A1W2PP34|A0A1W2PP34_HUMAN,tr|A0A1X7SBS1|A0A1X7SBS1_HUMAN" 11 4343.7952 3.49 136346 23173 4 4343.769043 1086.9561 Heterogeneous nuclear ribonucleoprotein U OS=Homo sapiens OX=9606 GN=HNRNPU PE=1 SV=6 3.73 4002.7 - 150859 - - - -6.0175 - 2.35 0.775 - 46.8 1 2 1 -0.0261 36 0 0 0 8.34E+05 2.39E+05 - - - 6.2162 1 221125_WJC_METTL3_EV_vs_WT_F09.23910.23910.3 6.97E-07 Dec-52 K.K[136.11]GPGEVAGTVTGQK[136.11].R "sp|Q86U44|MTA70_HUMAN,tr|F5H6D8|F5H6D8_HUMAN,tr|H0YFV6|H0YFV6_HUMAN,tr|B4DTN4|B4DTN4_HUMAN" 4 1343.738 0 136430 23910 3 1343.738129 448.9199 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 8.59 4135.9 - 167121 - - - 0.1116 - 2.523 0.602 - 244.3 1 2 0 0.0001 14 0 0 0 4.58E+03 3.65E+06 - - - 7.7111 0.9997 221125_WJC_METTL3_EV_vs_WT_F09.23912.23912.2 0.00628 26-Aug K.K[136.11]GPGEVAGTVTGQK[136.11].R "sp|Q86U44|MTA70_HUMAN,tr|F5H6D8|F5H6D8_HUMAN,tr|H0YFV6|H0YFV6_HUMAN,tr|B4DTN4|B4DTN4_HUMAN" 4 1343.738 0.001 136431 23912 2 1343.738089 672.8763 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 8.59 4136.2 - 64386.7 - - - 0.0819 - 1.585 0.456 - 145.9 1 2 0 0.0001 14 0 0 0 0.00E+00 5.50E+05 - - - 3.5648 0.9784 221125_WJC_METTL3_EV_vs_WT_F10.01664.01664.2 0.201 18-Jun K.K[136.11]DGSASAAAK[136.11].K "sp|P43243|MATR3_HUMAN,tr|B3KM87|B3KM87_HUMAN,tr|A8MXP9|A8MXP9_HUMAN,tr|A0A0R4J2E8|A0A0R4J2E8_HUMAN,tr|D6REM6|D6REM6_HUMAN" 5 920.4898 1.37 136450 1664 2 920.486588 461.2522 Matrin-3 OS=Homo sapiens OX=9606 GN=MATR3 PE=1 SV=2 8.59 1034.5 - 199552 - - - -3.5003 - 1.142 0.267 - 85.6 1 2 0 -0.0032 10 0 0 0 6.02E+07 4.41E+07 - - - 1.3827 0.9954 221125_WJC_METTL3_EV_vs_WT_F10.01763.01763.2 0.662 18-Jul K.KDGSASAAAK.K "sp|P43243|MATR3_HUMAN,tr|B3KM87|B3KM87_HUMAN,tr|A8MXP9|A8MXP9_HUMAN,tr|A0A0R4J2E8|A0A0R4J2E8_HUMAN,tr|D6REM6|D6REM6_HUMAN" 5 904.4614 1.36 136453 1763 2 904.459969 453.238 Matrin-3 OS=Homo sapiens OX=9606 GN=MATR3 PE=1 SV=2 8.59 1054.3 - 242711 - - - -1.5932 - 1.226 0.259 - 127.6 1 2 0 -0.0014 10 0 0 0 6.03E+07 4.42E+07 - - - 1.5223 0.9999 221125_WJC_METTL3_EV_vs_WT_F10.02353.02353.2 0.000546 14-Nov K.HAAENPGK.Y "sp|Q00839|HNRPU_HUMAN,tr|A0A1W2PQL0|A0A1W2PQL0_HUMAN,tr|A0A1W2PPL4|A0A1W2PPL4_HUMAN,tr|A0A1W2PQ74|A0A1W2PQ74_HUMAN,tr|Q5RI18|Q5RI18_HUMAN,tr|A0A1W2PP35|A0A1W2PP35_HUMAN,tr|A0A1W2PPS1|A0A1W2PPS1_HUMAN,tr|A0A1W2PRZ7|A0A1W2PRZ7_HUMAN,tr|A0A1W2PPH7|A0A1W2PPH7_HUMAN,tr|A0A1W2PQD4|A0A1W2PQD4_HUMAN,tr|A0A1W2PP34|A0A1W2PP34_HUMAN,tr|A0A1X7SBS1|A0A1X7SBS1_HUMAN" 12 822.3984 1 136462 2353 2 822.397714 412.2065 Heterogeneous nuclear ribonucleoprotein U OS=Homo sapiens OX=9606 GN=HNRNPU PE=1 SV=6 6.75 1174 - 6.16E+06 - - - -0.8524 - 2.254 0.509 - 470.9 1 2 0 -0.0007 8 0 0 0 8.89E+06 8.92E+06 - - - 5.2513 0.9999 221125_WJC_METTL3_EV_vs_WT_F10.02354.02354.2 0.00405 14-Oct K.HAAENPGK[136.11].Y "sp|Q00839|HNRPU_HUMAN,tr|A0A1W2PQL0|A0A1W2PQL0_HUMAN,tr|A0A1W2PPL4|A0A1W2PPL4_HUMAN,tr|A0A1W2PQ74|A0A1W2PQ74_HUMAN,tr|Q5RI18|Q5RI18_HUMAN,tr|A0A1W2PP35|A0A1W2PP35_HUMAN,tr|A0A1W2PPS1|A0A1W2PPS1_HUMAN,tr|A0A1W2PRZ7|A0A1W2PRZ7_HUMAN,tr|A0A1W2PPH7|A0A1W2PPH7_HUMAN,tr|A0A1W2PQD4|A0A1W2PQD4_HUMAN,tr|A0A1W2PP34|A0A1W2PP34_HUMAN,tr|A0A1X7SBS1|A0A1X7SBS1_HUMAN" 12 830.4126 1 136463 2354 2 830.41184 416.2136 Heterogeneous nuclear ribonucleoprotein U OS=Homo sapiens OX=9606 GN=HNRNPU PE=1 SV=6 6.75 1174.1 - 5.88E+06 - - - -0.9333 - 2.113 0.501 - 368.9 1 2 0 -0.0008 8 0 0 0 8.89E+06 8.92E+06 - - - 4.9974 0.9991 221125_WJC_METTL3_EV_vs_WT_F10.02362.02362.2 0.016 16-Oct K.DSKPSSTPR.S "sp|P06748|NPM_HUMAN,tr|E5RI98|E5RI98_HUMAN,tr|A0A7I2YQC0|A0A7I2YQC0_HUMAN,tr|A0A7I2V5S2|A0A7I2V5S2_HUMAN" 4 973.4829 1.66 136470 2362 2 973.481516 487.7487 Nucleophosmin OS=Homo sapiens OX=9606 GN=NPM1 PE=1 SV=2 8.75 1175.1 - 111570 - - - -1.394 - 1.514 0.35 - 177.1 1 2 0 -0.0014 9 0 0 0 4.46E+07 2.69E+07 - - - 2.8256 0.9984 221125_WJC_METTL3_EV_vs_WT_F10.02371.02371.2 0.000784 12-Nov K.HQEYEQK.L sp|O95628|CNOT4_HUMAN 1 960.4301 1.86 136475 2371 2 960.428297 481.2223 CCR4-NOT transcription complex subunit 4 OS=Homo sapiens OX=9606 GN=CNOT4 PE=1 SV=3 5.4 1176.3 - 6.47E+06 - - - -1.8877 - 1.852 0.213 - 431.4 1 2 0 -0.0018 7 0 0 0 2.27E+07 1.22E+07 - - - 2.5663 1 221125_WJC_METTL3_EV_vs_WT_F10.02372.02372.2 2.10E-06 16/20 R.RAEATAASTSR.S sp|O95721|SNP29_HUMAN 1 1119.5632 2.5 136476 2372 2 1119.561129 560.7889 Synaptosomal-associated protein 29 OS=Homo sapiens OX=9606 GN=SNAP29 PE=1 SV=1 9.6 1176.4 - 5.38E+06 - - - -1.8936 - 2.909 0.514 - 267.7 1 2 0 -0.0021 11 0 0 0 2.31E+07 9.25E+06 - - - 5.7254 0.9986 221125_WJC_METTL3_EV_vs_WT_F10.02373.02373.2 3.24E-05 12-Sep K.HQEYEQK[136.11].L sp|O95628|CNOT4_HUMAN 1 968.4443 1.86 136477 2373 2 968.442574 485.2294 CCR4-NOT transcription complex subunit 4 OS=Homo sapiens OX=9606 GN=CNOT4 PE=1 SV=3 5.4 1176.4 - 3.55E+06 - - - -1.7926 - 1.888 0.217 - 260.5 1 2 0 -0.0017 7 0 0 0 2.27E+07 1.22E+07 - - - 2.6569 1 221125_WJC_METTL3_EV_vs_WT_F10.02374.02374.2 0.000151 16/20 R.R[166.11]AEATAASTSR[166.11].S sp|O95721|SNP29_HUMAN 1 1139.5798 2.5 136478 2374 2 1139.57799 570.7972 Synaptosomal-associated protein 29 OS=Homo sapiens OX=9606 GN=SNAP29 PE=1 SV=1 9.6 1176.5 - 2.31E+06 - - - -1.5787 - 3.132 0.529 - 349.3 1 2 0 -0.0018 11 0 0 0 2.31E+07 9.25E+06 - - - 6.0361 1 221125_WJC_METTL3_EV_vs_WT_F10.02375.02375.3 8.91E-06 17/40 R.R[166.11]AEATAASTSR[166.11].S sp|O95721|SNP29_HUMAN 1 1139.5798 0.001 136479 2375 3 1139.578113 380.8672 Synaptosomal-associated protein 29 OS=Homo sapiens OX=9606 GN=SNAP29 PE=1 SV=1 9.6 1176.5 - 2.23E+06 - - - -1.4707 - 3.238 0.498 - 658.3 1 2 0 -0.0017 11 0 0 0 0.00E+00 7.41E+06 - - - 7.4296 0.9973 221125_WJC_METTL3_EV_vs_WT_F10.02376.02376.2 0.0643 16-Aug R.SSPSDTR[166.11]PK[136.11].C "sp|Q8IWS0|PHF6_HUMAN,tr|Q5JRC6|Q5JRC6_HUMAN,tr|A0A0D9SGE8|A0A0D9SGE8_HUMAN" 3 991.5053 1.74 136480 2376 2 991.503407 496.7599 PHD finger protein 6 OS=Homo sapiens OX=9606 GN=PHF6 PE=1 SV=1 8.46 1176.6 - 2.13E+06 - - - -1.9526 - 1.382 0.292 - 222.4 1 2 0 -0.0019 9 0 0 0 4.41E+07 2.53E+07 - - - 2.1331 0.914 221125_WJC_METTL3_EV_vs_WT_F10.02378.02378.2 0.0179 12-Aug S.PSDTR[166.11]PK[136.11].C "sp|Q8IWS0|PHF6_HUMAN,tr|Q5JRC6|Q5JRC6_HUMAN,tr|A0A0D9SGE8|A0A0D9SGE8_HUMAN" 3 817.4413 1.15 136482 2378 2 817.439635 409.7279 PHD finger protein 6 OS=Homo sapiens OX=9606 GN=PHF6 PE=1 SV=1 9.18 1176.7 - 1.91E+06 - - - -2.0209 - 1.518 0.313 - 150.3 1 1 0 -0.0017 7 0 0 0 2.88E+07 2.49E+07 - - - 2.6748 0.9993 221125_WJC_METTL3_EV_vs_WT_F10.02380.02380.2 0.000193 16-Aug K.KPEENPASK.F "sp|P23588|IF4B_HUMAN,tr|E7EX17|E7EX17_HUMAN" 2 998.5033 -1 136484 2380 2 998.50097 500.2589 Eukaryotic translation initiation factor 4B OS=Homo sapiens OX=9606 GN=EIF4B PE=1 SV=2 6.14 1176.9 - 1.66E+06 - - - -2.3085 - 2.055 0.358 - 182.7 1 2 0 -0.0023 9 0 0 0 0.00E+00 0.00E+00 - - - 3.7683 0.9938 221125_WJC_METTL3_EV_vs_WT_F10.02386.02386.2 0.0237 14-Jul R.DYGHSSSR[166.11].D "sp|Q96E39|RMXL1_HUMAN,sp|P38159|RBMX_HUMAN,tr|H3BUY5|H3BUY5_HUMAN,tr|H3BT71|H3BT71_HUMAN,tr|H0Y6E7|H0Y6E7_HUMAN" 5 917.3867 1.51 136490 2386 2 917.384907 459.7006 "RNA binding motif protein, X-linked-like-1 OS=Homo sapiens OX=9606 GN=RBMXL1 PE=1 SV=1" 6.74 1177.5 - 918613 - - - -1.9305 - 1.124 0.282 - 228 1 2 0 -0.0018 8 0 0 0 1.13E+08 7.45E+07 - - - 1.4758 0.9991 221125_WJC_METTL3_EV_vs_WT_F10.02393.02393.2 0.00122 20-Oct K.SLSSTSAGGKK.Q "sp|Q6W2J9|BCOR_HUMAN,tr|H7BZ37|H7BZ37_HUMAN,tr|H7C2V9|H7C2V9_HUMAN,tr|H7BYY2|H7BYY2_HUMAN,tr|H7C231|H7C231_HUMAN" 5 1021.5404 1.28 136496 2393 2 1021.53769 511.7775 BCL-6 corepressor OS=Homo sapiens OX=9606 GN=BCOR PE=1 SV=1 10 1178.4 - 593145 - - - -2.6411 - 1.886 0.402 - 196.4 1 2 0 -0.0027 11 0 0 0 2.59E+06 2.02E+06 - - - 3.7257 0.9984 221125_WJC_METTL3_EV_vs_WT_F10.02394.02394.2 0.00824 14-Sep R.DYGHSSSR.D "sp|Q96E39|RMXL1_HUMAN,sp|P38159|RBMX_HUMAN,tr|H3BUY5|H3BUY5_HUMAN,tr|H3BT71|H3BT71_HUMAN,tr|H0Y6E7|H0Y6E7_HUMAN" 5 907.3784 1.49 136497 2394 2 907.375876 454.6965 "RNA binding motif protein, X-linked-like-1 OS=Homo sapiens OX=9606 GN=RBMXL1 PE=1 SV=1" 6.74 1178.4 - 9.56E+06 - - - -2.7905 - 1.399 0.425 - 371.1 1 2 0 -0.0025 8 0 0 0 1.12E+08 7.54E+07 - - - 3.1919 0.9995 221125_WJC_METTL3_EV_vs_WT_F10.02399.02399.2 0.000493 16-Aug R.AQQQDKPPR.F sp|P48634|PRC2A_HUMAN 1 1066.552 1.21 136502 2399 2 1066.550082 534.2833 Protein PRRC2A OS=Homo sapiens OX=9606 GN=PRRC2A PE=1 SV=3 8.79 1178.9 - 374919 - - - -1.7571 - 1.686 0.414 - 255.3 1 2 0 -0.0019 9 0 0 0 2.58E+06 2.13E+06 - - - 3.6094 0.8273 221125_WJC_METTL3_EV_vs_WT_F10.02406.02406.2 0.297 18-Sep S.HTTISGGGSR.G sp|P04264|K2C1_HUMAN 1 971.4785 290.46 136507 2406 2 971.475458 486.7465 "Keratin, type II cytoskeletal 1 OS=Homo sapiens OX=9606 GN=KRT1 PE=1 SV=6" 9.76 1179.9 - 1.47E+07 - - - -3.087 - 1.551 0.324 - 172.8 1 1 0 -0.003 10 0 0 0 2.10E+08 7.22E+05 - - - 2.6582 0.9992 221125_WJC_METTL3_EV_vs_WT_F10.02418.02418.2 3.72E-06 20-Dec K.GGQHSQAAPVK[136.11].W sp|Q5T3J3|LRIF1_HUMAN 1 1086.5662 1.97 136519 2418 2 1086.561794 544.2904 Ligand-dependent nuclear receptor-interacting factor 1 OS=Homo sapiens OX=9606 GN=LRIF1 PE=1 SV=1 8.76 1181.2 - 213733 - - - -4.0145 - 2.153 0.588 - 537.3 1 2 0 -0.0044 11 0 0 0 6.46E+06 3.28E+06 - - - 5.4571 0.9983 221125_WJC_METTL3_EV_vs_WT_F10.02419.02419.2 0.000335 18-Aug R.ANQDTNTAQR[166.11].M "sp|Q86VI3|IQGA3_HUMAN,tr|F2Z2E2|F2Z2E2_HUMAN" 2 1127.5195 0.94 136520 2419 2 1127.514506 564.767 Ras GTPase-activating-like protein IQGAP3 OS=Homo sapiens OX=9606 GN=IQGAP3 PE=1 SV=2 5.88 1181.3 - 90824.5 - - - -4.4141 - 1.912 0.523 - 358.9 1 2 0 -0.005 10 0 0 0 7.56E+05 8.05E+05 - - - 4.7115 0.907 221125_WJC_METTL3_EV_vs_WT_F10.02422.02422.2 0.00623 16-Dec A.GAHLQGGAK[136.11].R "sp|P04406|G3P_HUMAN,tr|E7EUT5|E7EUT5_HUMAN" 2 845.4599 1.15 136521 2422 2 845.456553 423.7372 Glyceraldehyde-3-phosphate dehydrogenase OS=Homo sapiens OX=9606 GN=GAPDH PE=1 SV=3 8.76 1181.8 - 1.17E+06 - - - -3.9588 - 2.007 0.421 - 526.4 1 1 0 -0.0033 9 0 0 0 1.28E+07 1.11E+07 - - - 4.1649 0.999 221125_WJC_METTL3_EV_vs_WT_F10.02424.02424.2 0.00135 16-Oct R.RDGSYGSGR.S "sp|Q08170|SRSF4_HUMAN,tr|A0A0D9SGD2|A0A0D9SGD2_HUMAN,tr|A0A0D9SEM4|A0A0D9SEM4_HUMAN" 3 953.4315 1.21 136523 2424 2 953.429011 477.723 Serine\arginine-rich splicing factor 4 OS=Homo sapiens OX=9606 GN=SRSF4 PE=1 SV=2 8.75 1182 - 986004 - - - -2.6179 - 2.385 0.281 - 152.7 1 2 0 -0.0025 9 0 0 0 6.54E+06 5.42E+06 - - - 3.6303 1 221125_WJC_METTL3_EV_vs_WT_F10.02427.02427.2 4.94E-07 16-Nov R.TEC[160.03]NQC[160.03]GDR[166.11].G tr|H7BY36|H7BY36_HUMAN 1 1148.4214 0.76 136526 2427 2 1148.418309 575.218 RNA-binding protein EWS (Fragment) OS=Homo sapiens OX=9606 GN=EWSR1 PE=1 SV=1 4.37 1182.3 - 528151 - - - -2.7142 - 2.275 0.716 - 612.5 1 2 0 -0.0031 9 0 0 0 3.49E+06 4.56E+06 - - - 6.7064 0.9972 221125_WJC_METTL3_EV_vs_WT_F10.02430.02430.3 0.000501 13/32 R.QLNENK[136.11]QER[166.11].D sp|P26368|U2AF2_HUMAN 1 1175.6014 0.94 136529 2430 3 1175.5966 392.8744 Splicing factor U2AF 65 kDa subunit OS=Homo sapiens OX=9606 GN=U2AF2 PE=1 SV=4 6.14 1182.7 - 422721 - - - -4.0566 - 2.257 0.401 - 370.6 1 2 1 -0.0048 9 0 0 0 7.84E+07 8.30E+07 - - - 5.4628 1 221125_WJC_METTL3_EV_vs_WT_F10.02431.02431.2 3.77E-07 16-Sep R.TEC[160.03]NQC[160.03]GDR.G tr|H7BY36|H7BY36_HUMAN 1 1138.4132 0.76 136530 2431 2 1138.410348 570.2139 RNA-binding protein EWS (Fragment) OS=Homo sapiens OX=9606 GN=EWSR1 PE=1 SV=1 4.37 1182.8 - 387198 - - - -2.4666 - 1.977 0.64 - 444.1 1 2 0 -0.0028 9 0 0 0 3.49E+06 4.56E+06 - - - 5.739 0.9992 221125_WJC_METTL3_EV_vs_WT_F10.02438.02438.2 4.35E-05 18-Nov K.AGAHLQGGAK[136.11].R "sp|P04406|G3P_HUMAN,tr|E7EUT5|E7EUT5_HUMAN" 2 916.497 1.03 136534 2438 2 916.49399 459.2558 Glyceraldehyde-3-phosphate dehydrogenase OS=Homo sapiens OX=9606 GN=GAPDH PE=1 SV=3 8.8 1183.6 - 1.68E+06 - - - -3.2995 - 1.883 0.498 - 398.8 1 2 0 -0.003 10 0 0 0 1.02E+07 9.87E+06 - - - 4.4848 0.9566 221125_WJC_METTL3_EV_vs_WT_F10.02440.02440.2 0.0588 16-Jul R.QLNENK[136.11]QER[166.11].D sp|P26368|U2AF2_HUMAN 1 1175.6014 1.15 136536 2440 2 1175.597213 588.808 Splicing factor U2AF 65 kDa subunit OS=Homo sapiens OX=9606 GN=U2AF2 PE=1 SV=4 6.14 1183.9 - 298853 - - - -3.5352 - 1.616 0.325 - 247.6 1 2 1 -0.0042 9 0 0 0 1.61E+07 1.40E+07 - - - 2.8287 0.9851 221125_WJC_METTL3_EV_vs_WT_F10.02442.02442.2 0.00438 16-Aug R.QLNENKQER.D sp|P26368|U2AF2_HUMAN 1 1157.5789 1.15 136538 2442 2 1157.575987 579.7967 Splicing factor U2AF 65 kDa subunit OS=Homo sapiens OX=9606 GN=U2AF2 PE=1 SV=4 6.14 1184.1 - 177368 - - - -2.5156 - 1.64 0.366 - 299.7 1 2 1 -0.0029 9 0 0 0 1.61E+07 1.40E+07 - - - 3.1745 0.9975 221125_WJC_METTL3_EV_vs_WT_F10.02446.02446.3 0.000918 Dec-40 K.NSSAVEQDHAK.T sp|Q9NXV6|CARF_HUMAN 1 1184.5422 0.98 136540 2446 3 1184.53579 395.8547 CDKN2A-interacting protein OS=Homo sapiens OX=9606 GN=CDKN2AIP PE=1 SV=3 5.32 1184.7 - 2.01E+06 - - - -5.3936 - 1.965 0.411 - 240.5 1 2 0 -0.0064 11 0 0 0 1.03E+07 1.06E+07 - - - 5.0394 0.9994 221125_WJC_METTL3_EV_vs_WT_F10.02452.02452.2 5.39E-06 20-Dec K.NSSAVEQDHAK[136.11].T sp|Q9NXV6|CARF_HUMAN 1 1192.5564 1.52 136546 2452 2 1192.552295 597.2855 CDKN2A-interacting protein OS=Homo sapiens OX=9606 GN=CDKN2AIP PE=1 SV=3 5.32 1185.3 - 366378 - - - -3.4246 - 2.292 0.545 - 674.5 1 2 0 -0.0041 11 0 0 0 2.22E+06 1.46E+06 - - - 5.3089 0.9974 221125_WJC_METTL3_EV_vs_WT_F10.02460.02460.2 0.000479 20-Oct R.QQEEQTGSGQR.S tr|H0Y5H6|H0Y5H6_HUMAN 1 1246.5538 0.97 136552 2460 2 1246.552098 624.2842 Ubiquitin-associated protein 2-like (Fragment) OS=Homo sapiens OX=9606 GN=UBAP2L PE=1 SV=1 4.53 1186.4 - 946750 - - - -1.371 - 1.859 0.158 - 421 1 2 0 -0.0017 11 0 0 0 4.41E+06 4.55E+06 - - - 1.8848 0.9848 221125_WJC_METTL3_EV_vs_WT_F10.02461.02461.2 0.0483 14-Jun R.QYNEEGRK.A "sp|Q9BUJ2|HNRL1_HUMAN,tr|A0A0A0MRA5|A0A0A0MRA5_HUMAN,tr|M0R3F1|M0R3F1_HUMAN,tr|B7Z4B8|B7Z4B8_HUMAN" 4 1022.4781 2.68 136553 2461 2 1022.473919 512.2463 Heterogeneous nuclear ribonucleoprotein U-like protein 1 OS=Homo sapiens OX=9606 GN=HNRNPUL1 PE=1 SV=2 6.14 1186.5 - 776347 - - - -4.1106 - 1.199 0.328 - 132.3 1 2 0 -0.0042 8 0 0 0 3.32E+07 1.24E+07 - - - 2.0096 0.9948 221125_WJC_METTL3_EV_vs_WT_F10.02467.02467.2 0.0024 14-Nov R.YRQDDDQR.S "sp|Q7KZF4|SND1_HUMAN,tr|H7C597|H7C597_HUMAN" 2 1094.4741 1.43 136559 2467 2 1094.471561 548.2443 Staphylococcal nuclease domain-containing protein 1 OS=Homo sapiens OX=9606 GN=SND1 PE=1 SV=1 4.43 1187.1 - 389075 - - - -2.3198 - 2.186 0.391 - 553.4 1 2 1 -0.0025 8 0 0 0 6.93E+06 4.85E+06 - - - 4.2868 0.9967 221125_WJC_METTL3_EV_vs_WT_F10.02483.02483.2 0.00689 14-Aug R.QYNEEGR[166.11]K[136.11].A "sp|Q9BUJ2|HNRL1_HUMAN,tr|A0A0A0MRA5|A0A0A0MRA5_HUMAN,tr|M0R3F1|M0R3F1_HUMAN,tr|B7Z4B8|B7Z4B8_HUMAN" 4 1040.5006 2.68 136566 2483 2 1040.497021 521.2576 Heterogeneous nuclear ribonucleoprotein U-like protein 1 OS=Homo sapiens OX=9606 GN=HNRNPUL1 PE=1 SV=2 6.14 1189 - 1.61E+06 - - - -3.432 - 1.562 0.348 - 301 1 2 0 -0.0036 8 0 0 0 3.32E+07 1.24E+07 - - - 2.9552 0.9979 221125_WJC_METTL3_EV_vs_WT_F10.02488.02488.2 0.0545 16-Aug K.ASDADRPC[160.03]R.K "sp|Q86U44|MTA70_HUMAN,tr|H0YFV6|H0YFV6_HUMAN" 2 1046.4563 0 136569 2488 2 1046.453475 524.2354 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 6 1189.5 - 5.45E+06 - - - -2.7388 - 1.554 0.35 - 131.6 1 2 0 -0.0029 9 0 0 0 3.61E+08 9.93E+10 - - - 2.9006 0.9879 221125_WJC_METTL3_EV_vs_WT_F10.02509.02509.2 0.00716 14-Sep R.DLVHSNKK.E "sp|Q9Y2W1|TR150_HUMAN,tr|A0A3B3ITZ9|A0A3B3ITZ9_HUMAN" 2 939.5138 2.44 136577 2509 2 939.508783 470.7642 Thyroid hormone receptor-associated protein 3 OS=Homo sapiens OX=9606 GN=THRAP3 PE=1 SV=2 8.6 1192.1 - 6.52E+06 - - - -5.3187 - 1.647 0.333 - 336.1 1 2 0 -0.005 8 0 0 0 3.55E+09 1.46E+09 - - - 3.0038 0.9946 221125_WJC_METTL3_EV_vs_WT_F10.02515.02515.2 0.0139 14-Sep R.DLVHSNK[136.11]K[136.11].E "sp|Q9Y2W1|TR150_HUMAN,tr|A0A3B3ITZ9|A0A3B3ITZ9_HUMAN" 2 955.5422 2.44 136579 2515 2 955.5382 478.7784 Thyroid hormone receptor-associated protein 3 OS=Homo sapiens OX=9606 GN=THRAP3 PE=1 SV=2 8.6 1192.9 - 1.03E+07 - - - -4.1652 - 1.674 0.324 - 346.4 1 2 0 -0.004 8 0 0 0 3.55E+09 1.46E+09 - - - 2.9867 0.7752 221125_WJC_METTL3_EV_vs_WT_F10.02557.02557.2 2.11 16-May R.QTQVNEATK.A "sp|Q8WWY3|PRP31_HUMAN,tr|E7EVX8|E7EVX8_HUMAN" 2 1017.5091 999 136594 2557 2 1017.505941 509.7618 U4\U6 small nuclear ribonucleoprotein Prp31 OS=Homo sapiens OX=9606 GN=PRPF31 PE=1 SV=2 6 1198.5 - 1.37E+06 - - - -3.0928 - 1.138 0.069 - 88.9 10 2 0 -0.0031 9 0 0 0 2.95E+07 0.00E+00 - - - -0.5231 0.7849 221125_WJC_METTL3_EV_vs_WT_F10.02570.02570.2 0.0934 18-Oct R.EKEAAEQAER.S "sp|Q969G3|SMCE1_HUMAN,tr|A0A2R8Y855|A0A2R8Y855_HUMAN,tr|A0A2R8YES3|A0A2R8YES3_HUMAN,tr|A0A2U3TZQ7|A0A2U3TZQ7_HUMAN,tr|A0A2R8Y7U4|A0A2R8Y7U4_HUMAN,tr|B4DGM3|B4DGM3_HUMAN,tr|A0A2R8Y4T4|A0A2R8Y4T4_HUMAN,tr|A0A2R8Y7I9|A0A2R8Y7I9_HUMAN,tr|A0A2R8Y765|A0A2R8Y765_HUMAN" 9 1159.5469 2.22 136602 2570 2 1159.543835 580.7807 SWI\SNF-related matrix-associated actin-dependent regulator of chromatin subfamily E member 1 OS=Homo sapiens OX=9606 GN=SMARCE1 PE=1 SV=2 4.49 1200 - 732561 - - - -2.6691 - 1.426 0.114 - 252.1 1 2 1 -0.0031 10 0 0 0 8.36E+06 3.76E+06 - - - 0.8726 0.9198 221125_WJC_METTL3_EV_vs_WT_F10.02579.02579.2 0.0457 20-Sep R.HPAEAPNNGAR.L "sp|O14654|IRS4_HUMAN,tr|A0A804CF45|A0A804CF45_HUMAN" 2 1132.5374 1.38 136609 2579 2 1132.530075 567.276 Insulin receptor substrate 4 OS=Homo sapiens OX=9606 GN=IRS4 PE=1 SV=1 6.75 1201.1 - 464104 - - - -6.4404 - 1.795 0.179 - 277.1 1 2 0 -0.0073 11 0 0 0 1.84E+07 1.34E+07 - - - 1.9434 0.8133 221125_WJC_METTL3_EV_vs_WT_F10.02580.02580.2 0.246 18-Oct R.EK[136.11]EAAEQAER[166.11].S "sp|Q969G3|SMCE1_HUMAN,tr|A0A2R8Y855|A0A2R8Y855_HUMAN,tr|A0A2R8YES3|A0A2R8YES3_HUMAN,tr|A0A2U3TZQ7|A0A2U3TZQ7_HUMAN,tr|A0A2R8Y7U4|A0A2R8Y7U4_HUMAN,tr|B4DGM3|B4DGM3_HUMAN,tr|A0A2R8Y4T4|A0A2R8Y4T4_HUMAN,tr|A0A2R8Y7I9|A0A2R8Y7I9_HUMAN,tr|A0A2R8Y765|A0A2R8Y765_HUMAN" 9 1177.5694 2.22 136610 2580 2 1177.563903 589.792 SWI\SNF-related matrix-associated actin-dependent regulator of chromatin subfamily E member 1 OS=Homo sapiens OX=9606 GN=SMARCE1 PE=1 SV=2 4.49 1201.3 - 387275 - - - -4.6681 - 1.445 0.277 - 317.1 1 2 1 -0.0055 10 0 0 0 8.36E+06 3.76E+06 - - - 2.1127 0.882 221125_WJC_METTL3_EV_vs_WT_F10.02583.02583.3 0.0435 Oct-36 R.EK[136.11]EAAEQAER[166.11].S "sp|Q969G3|SMCE1_HUMAN,tr|A0A2R8Y855|A0A2R8Y855_HUMAN,tr|A0A2R8YES3|A0A2R8YES3_HUMAN,tr|A0A2U3TZQ7|A0A2U3TZQ7_HUMAN,tr|A0A2R8Y7U4|A0A2R8Y7U4_HUMAN,tr|B4DGM3|B4DGM3_HUMAN,tr|A0A2R8Y4T4|A0A2R8Y4T4_HUMAN,tr|A0A2R8Y7I9|A0A2R8Y7I9_HUMAN,tr|A0A2R8Y765|A0A2R8Y765_HUMAN" 9 1177.5694 1.86 136611 2583 3 1177.564456 393.5304 SWI\SNF-related matrix-associated actin-dependent regulator of chromatin subfamily E member 1 OS=Homo sapiens OX=9606 GN=SMARCE1 PE=1 SV=2 4.49 1201.6 - 2.09E+06 - - - -4.1985 - 1.772 0.207 - 207 1 2 1 -0.0049 10 0 0 0 3.97E+07 2.13E+07 - - - 2.5173 0.9989 221125_WJC_METTL3_EV_vs_WT_F10.02584.02584.3 7.51E-06 Dec-40 R.HPAEAPNNGAR[166.11].L "sp|O14654|IRS4_HUMAN,tr|A0A804CF45|A0A804CF45_HUMAN" 2 1142.5456 0.001 136612 2584 3 1142.541397 381.8558 Insulin receptor substrate 4 OS=Homo sapiens OX=9606 GN=IRS4 PE=1 SV=1 6.75 1201.7 - 2.56E+06 - - - -3.7128 - 2.411 0.33 - 382.7 1 2 0 -0.0042 11 0 0 0 0.00E+00 6.00E+07 - - - 4.718 0.9983 221125_WJC_METTL3_EV_vs_WT_F10.02586.02586.2 0.0301 18-Oct R.VTQVDGHSSK.N "sp|O43324|MCA3_HUMAN,tr|C9J1V9|C9J1V9_HUMAN,tr|H0YAL7|H0YAL7_HUMAN,tr|D6RBD7|D6RBD7_HUMAN" 4 1056.52 0.9 136614 2586 2 1056.516418 529.2673 Eukaryotic translation elongation factor 1 epsilon-1 OS=Homo sapiens OX=9606 GN=EEF1E1 PE=1 SV=1 6.71 1201.8 - 1.08E+06 - - - -3.3781 - 1.911 0.377 - 512.6 1 2 0 -0.0036 10 0 0 0 1.25E+07 1.39E+07 - - - 3.6321 0.9996 221125_WJC_METTL3_EV_vs_WT_F10.02588.02588.2 0.000688 24-Jul R.KSSVNGSSATSSG.- "sp|P35226|BMI1_HUMAN,tr|R4GMX3|R4GMX3_HUMAN" 2 1167.5368 0.83 136616 2588 2 1167.534593 584.7757 Polycomb complex protein BMI-1 OS=Homo sapiens OX=9606 GN=BMI1 PE=1 SV=2 8.75 1202.1 - 797686 - - - -1.856 - 1.598 0.52 - 107.6 1 2 0 -0.0022 13 0 0 0 4.96E+06 6.00E+06 - - - 4.0841 0.9996 221125_WJC_METTL3_EV_vs_WT_F10.02589.02589.2 0.0221 16-Sep K.KVVVSPTKK.V "sp|P19338|NUCL_HUMAN,tr|A0A7I2V506|A0A7I2V506_HUMAN,tr|A0A7I2V699|A0A7I2V699_HUMAN,tr|A0A7I2V2U7|A0A7I2V2U7_HUMAN,tr|A0A7I2V3F3|A0A7I2V3F3_HUMAN,tr|A0A7I2V428|A0A7I2V428_HUMAN,tr|A0A7I2V349|A0A7I2V349_HUMAN,tr|H7BY16|H7BY16_HUMAN,tr|A0A7I2V5M5|A0A7I2V5M5_HUMAN,tr|A0A7I2V2S8|A0A7I2V2S8_HUMAN,tr|C9JLB1|C9JLB1_HUMAN" 11 984.6332 0.61 136617 2589 2 984.631524 493.3239 Nucleolin OS=Homo sapiens OX=9606 GN=NCL PE=1 SV=3 10.3 1202.2 - 646488 - - - -1.6686 - 1.742 0.444 - 256.5 1 2 0 -0.0016 9 0 0 0 6.67E+06 1.09E+07 - - - 3.9256 0.9997 221125_WJC_METTL3_EV_vs_WT_F10.02590.02590.2 5.85E-06 13/18 K.K[136.11]VDTTPNQGK[136.11].K "sp|Q9P2E9|RRBP1_HUMAN,tr|A2A2S5|A2A2S5_HUMAN" 2 1102.5953 0.86 136618 2590 2 1102.592311 552.3049 Ribosome-binding protein 1 OS=Homo sapiens OX=9606 GN=RRBP1 PE=1 SV=5 8.59 1202.3 - 627716 - - - -2.7444 - 2.392 0.564 - 608.9 1 2 0 -0.003 10 0 0 0 1.44E+07 1.68E+07 - - - 5.6401 0.9989 221125_WJC_METTL3_EV_vs_WT_F10.02598.02598.2 0.000146 18-Nov R.VTQVDGHSSK[136.11].N "sp|O43324|MCA3_HUMAN,tr|C9J1V9|C9J1V9_HUMAN,tr|H0YAL7|H0YAL7_HUMAN,tr|D6RBD7|D6RBD7_HUMAN" 4 1064.5342 0.9 136624 2598 2 1064.530728 533.2744 Eukaryotic translation elongation factor 1 epsilon-1 OS=Homo sapiens OX=9606 GN=EEF1E1 PE=1 SV=1 6.71 1203.3 - 1.68E+06 - - - -3.2493 - 1.906 0.427 - 439.8 1 2 0 -0.0035 10 0 0 0 1.26E+07 1.39E+07 - - - 3.9941 0.9989 221125_WJC_METTL3_EV_vs_WT_F10.02603.02603.2 0.000705 16-Sep R.DTNESTNTR.V sp|P49755|TMEDA_HUMAN 1 1036.4421 0.21 136629 2603 2 1036.438545 519.2283 Transmembrane emp24 domain-containing protein 10 OS=Homo sapiens OX=9606 GN=TMED10 PE=1 SV=2 4.37 1203.7 - 1.94E+06 - - - -3.4599 - 1.831 0.477 - 432.6 1 2 0 -0.0036 9 0 0 0 8.94E+06 4.32E+07 - - - 4.3129 0.9983 221125_WJC_METTL3_EV_vs_WT_F10.02606.02606.3 0.00466 Oct-40 R.LAQQPHQNQAK.L "sp|Q9BPX3|CND3_HUMAN,tr|D6RA93|D6RA93_HUMAN" 2 1261.6527 1.04 136632 2606 3 1261.648516 421.5582 Condensin complex subunit 3 OS=Homo sapiens OX=9606 GN=NCAPG PE=1 SV=1 8.76 1204 - 787744 - - - -3.3424 - 2.141 0.303 - 185.1 1 2 0 -0.0042 11 0 0 0 2.04E+07 1.97E+07 - - - 4.0796 0.9926 221125_WJC_METTL3_EV_vs_WT_F10.02615.02615.3 0.0626 Oct-40 R.LAQQPHQNQAK[136.11].L "sp|Q9BPX3|CND3_HUMAN,tr|D6RA93|D6RA93_HUMAN" 2 1269.6669 1.04 136639 2615 3 1269.661408 424.2296 Condensin complex subunit 3 OS=Homo sapiens OX=9606 GN=NCAPG PE=1 SV=1 8.76 1205.1 - 2.78E+06 - - - -4.3515 - 2.011 0.27 - 193.7 1 2 0 -0.0055 11 0 0 0 2.04E+07 1.97E+07 - - - 3.5334 0.9946 221125_WJC_METTL3_EV_vs_WT_F10.02621.02621.3 2.29E-06 Dec-36 R.QQEEEK[136.11]AEAR[166.11].A sp|O43818|U3IP2_HUMAN 1 1234.5909 1.32 136645 2621 3 1234.584498 412.5376 U3 small nucleolar RNA-interacting protein 2 OS=Homo sapiens OX=9606 GN=RRP9 PE=1 SV=1 4.49 1205.8 - 642697 - - - -5.1564 - 1.895 0.468 - 267.1 1 2 1 -0.0064 10 0 0 0 6.58E+06 4.97E+06 - - - 5.6228 0.996 221125_WJC_METTL3_EV_vs_WT_F10.02624.02624.2 0.00891 20-Jul R.LAQQPHQNQAK.L "sp|Q9BPX3|CND3_HUMAN,tr|D6RA93|D6RA93_HUMAN" 2 1261.6527 -1 136648 2624 2 1261.6482 631.8336 Condensin complex subunit 3 OS=Homo sapiens OX=9606 GN=NCAPG PE=1 SV=1 8.76 1206.2 - 300351 - - - -3.5929 - 1.391 0.4 - 152 1 2 0 -0.0045 11 0 0 0 0.00E+00 0.00E+00 - - - 2.8868 0.9982 221125_WJC_METTL3_EV_vs_WT_F10.02628.02628.2 0.000761 20-Dec R.HPAEAPNNGAR[166.11].L "sp|O14654|IRS4_HUMAN,tr|A0A804CF45|A0A804CF45_HUMAN" 2 1142.5456 1.35 136650 2628 2 1142.5406 572.2801 Insulin receptor substrate 4 OS=Homo sapiens OX=9606 GN=IRS4 PE=1 SV=1 6.75 1206.7 - 1.23E+06 - - - -4.4103 - 1.923 0.504 - 394.2 1 2 0 -0.005 11 0 0 0 1.84E+07 1.37E+07 - - - 4.5309 0.9995 221125_WJC_METTL3_EV_vs_WT_F10.02633.02633.3 5.93E-07 16/44 K.AAEEEAGSEQKR.D sp|Q96T58|MINT_HUMAN 1 1303.6004 1.36 136655 2633 3 1303.594378 435.5408 Msx2-interacting protein OS=Homo sapiens OX=9606 GN=SPEN PE=1 SV=1 4.49 1207.3 - 348447 - - - -4.6364 - 2.804 0.419 - 468.5 1 2 0 -0.006 12 0 0 0 8.89E+06 6.53E+06 - - - 6.0677 0.9999 221125_WJC_METTL3_EV_vs_WT_F10.02642.02642.3 4.49E-09 15/44 K.AAEEEAGSEQK[136.11]R[166.11].D sp|Q96T58|MINT_HUMAN 1 1321.6229 1.36 136662 2642 3 1321.618313 441.5482 Msx2-interacting protein OS=Homo sapiens OX=9606 GN=SPEN PE=1 SV=1 4.49 1208.4 - 587059 - - - -3.4647 - 2.853 0.509 - 461 1 2 0 -0.0046 12 0 0 0 8.89E+06 6.53E+06 - - - 7.1195 1 221125_WJC_METTL3_EV_vs_WT_F10.02644.02644.2 1.13E-07 14/24 R.TSAQAASSQSANK[136.11].T sp|Q92545|TM131_HUMAN 1 1257.6041 1.86 136664 2644 2 1257.598936 629.8093 Transmembrane protein 131 OS=Homo sapiens OX=9606 GN=TMEM131 PE=1 SV=3 8.41 1208.7 - 318510 - - - -4.0728 - 2.762 0.601 - 815.7 1 2 0 -0.0051 13 0 0 0 4.50E+06 2.41E+06 - - - 6.0859 0.9972 221125_WJC_METTL3_EV_vs_WT_F10.02650.02650.2 0.15 16-Sep R.QEEEESVK[136.11]K[136.11].E sp|Q9Y5A9|YTHD2_HUMAN 1 1120.5583 1.58 136668 2650 2 1120.554099 561.2864 YTH domain-containing family protein 2 OS=Homo sapiens OX=9606 GN=YTHDF2 PE=1 SV=2 4.49 1209.3 - 959981 - - - -3.7339 - 1.79 0.354 - 293.1 1 2 0 -0.0042 9 0 0 0 3.86E+07 2.45E+07 - - - 3.3387 1 221125_WJC_METTL3_EV_vs_WT_F10.02655.02655.2 6.14E-07 13/24 R.TSAQAASSQSANK.T sp|Q92545|TM131_HUMAN 1 1249.5899 1.86 136673 2655 2 1249.586961 625.8022 Transmembrane protein 131 OS=Homo sapiens OX=9606 GN=TMEM131 PE=1 SV=3 8.41 1210 - 664591 - - - -2.3184 - 2.699 0.63 - 685.7 1 2 0 -0.0029 13 0 0 0 4.50E+06 2.41E+06 - - - 6.2415 0.9986 221125_WJC_METTL3_EV_vs_WT_F10.02657.02657.2 0.00242 18-Oct R.SVNPNKPATK.D "sp|Q06787|FMR1_HUMAN,tr|A0A087WY29|A0A087WY29_HUMAN,tr|R9WNI0|R9WNI0_HUMAN,tr|A8MQB8|A8MQB8_HUMAN,tr|A0A087WXI3|A0A087WXI3_HUMAN,tr|Q8IXW7|Q8IXW7_HUMAN,tr|G3V0J0|G3V0J0_HUMAN" 7 1054.5771 1.92 136675 2657 2 1054.57363 528.2958 Synaptic functional regulator FMR1 OS=Homo sapiens OX=9606 GN=FMR1 PE=1 SV=1 10 1210.3 - 594461 - - - -3.298 - 1.905 0.402 - 270.4 1 2 0 -0.0035 10 0 0 0 6.33E+07 3.30E+07 - - - 3.808 0.907 221125_WJC_METTL3_EV_vs_WT_F10.02662.02662.2 2.06 16-Jun K.ASDADR[166.11]PC[160.03]R[166.11].K "sp|Q86U44|MTA70_HUMAN,tr|H0YFV6|H0YFV6_HUMAN" 2 1066.4729 0.03 136679 2662 2 1066.469608 534.2437 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 6 1210.9 - 2.82E+06 - - - -3.069 - 1.09 0.112 - 73.6 1 2 0 -0.0033 9 0 0 0 9.74E+05 2.86E+07 - - - 0.1165 0.9973 221125_WJC_METTL3_EV_vs_WT_F10.02664.02664.2 1.52E-05 16-Sep R.QEEEESVKK.E sp|Q9Y5A9|YTHD2_HUMAN 1 1104.5299 1.58 136681 2664 2 1104.525857 553.2722 YTH domain-containing family protein 2 OS=Homo sapiens OX=9606 GN=YTHDF2 PE=1 SV=2 4.49 1211.1 - 4.48E+06 - - - -3.645 - 1.685 0.376 - 301 1 2 0 -0.004 9 0 0 0 3.86E+07 2.45E+07 - - - 3.3264 1 221125_WJC_METTL3_EV_vs_WT_F10.02670.02670.2 1.05E-06 22-Oct K.DGGQTESNEEGK[136.11].E "sp|Q14157|UBP2L_HUMAN,tr|Q5VU78|Q5VU78_HUMAN,tr|F8W726|F8W726_HUMAN,tr|Q5VU81|Q5VU81_HUMAN,tr|Q5VU79|Q5VU79_HUMAN,tr|Q5VU80|Q5VU80_HUMAN,tr|Q5VU77|Q5VU77_HUMAN" 7 1257.5201 2.43 136687 2670 2 1257.515187 629.7673 Ubiquitin-associated protein 2-like OS=Homo sapiens OX=9606 GN=UBAP2L PE=1 SV=2 4 1211.7 - 355675 - - - -3.8695 - 2.349 0.687 - 481.9 1 2 0 -0.0049 12 0 0 0 4.22E+07 1.74E+07 - - - 6.3606 0.9994 221125_WJC_METTL3_EV_vs_WT_F10.02676.02676.2 4.99E-06 22-Dec K.DGGQTESNEEGK.E "sp|Q14157|UBP2L_HUMAN,tr|Q5VU78|Q5VU78_HUMAN,tr|F8W726|F8W726_HUMAN,tr|Q5VU81|Q5VU81_HUMAN,tr|Q5VU79|Q5VU79_HUMAN,tr|Q5VU80|Q5VU80_HUMAN,tr|Q5VU77|Q5VU77_HUMAN" 7 1249.5059 2.43 136691 2676 2 1249.501575 625.7602 Ubiquitin-associated protein 2-like OS=Homo sapiens OX=9606 GN=UBAP2L PE=1 SV=2 4 1212.5 - 3.38E+06 - - - -3.4238 - 2.661 0.519 - 777.1 1 2 0 -0.0043 12 0 0 0 4.22E+07 1.74E+07 - - - 5.4481 0.9414 221125_WJC_METTL3_EV_vs_WT_F10.02680.02680.2 0.186 14-Aug K.NR[166.11]PGPQTR[166.11].S "sp|O14744|ANM5_HUMAN,tr|C9JSX3|C9JSX3_HUMAN,tr|G3V580|G3V580_HUMAN,tr|G3V2L6|G3V2L6_HUMAN,tr|G3V5L5|G3V5L5_HUMAN" 5 944.5055 5.87 136695 2680 2 944.502842 473.26 Protein arginine N-methyltransferase 5 OS=Homo sapiens OX=9606 GN=PRMT5 PE=1 SV=4 12 1212.8 - 1.21E+06 - - - -2.8163 - 1.402 0.064 - 115.9 3 2 0 -0.0027 8 0 0 0 1.37E+08 2.33E+07 - - - 0.3188 0.9993 221125_WJC_METTL3_EV_vs_WT_F10.02682.02682.2 0.0525 16-Nov K.STDEVDSKR.L "sp|Q01082|SPTB2_HUMAN,tr|A0A087WUZ3|A0A087WUZ3_HUMAN" 2 1035.4833 1.4 136697 2682 2 1035.480433 518.7489 "Spectrin beta chain, non-erythrocytic 1 OS=Homo sapiens OX=9606 GN=SPTBN1 PE=1 SV=2" 4.56 1213.1 - 507595 - - - -2.7369 - 2.037 0.418 - 653.6 1 2 0 -0.0028 9 0 0 0 5.64E+06 4.03E+06 - - - 4.1858 0.9531 221125_WJC_METTL3_EV_vs_WT_F10.02683.02683.2 0.000546 18-Oct R.SR[166.11]VEQEQEAK[136.11].M "sp|Q9H6Z4|RANB3_HUMAN,tr|B7Z7F3|B7Z7F3_HUMAN,tr|K7EIJ4|K7EIJ4_HUMAN" 3 1220.6116 0.55 136698 2683 2 1220.611399 611.3131 Ran-binding protein 3 OS=Homo sapiens OX=9606 GN=RANBP3 PE=1 SV=1 4.78 1213.2 - 486912 - - - -0.1639 - 1.87 0.055 - 283.5 1 2 1 -0.0002 10 0 0 0 9.58E+05 1.73E+06 - - - 1.1944 0.9962 221125_WJC_METTL3_EV_vs_WT_F10.02684.02684.2 0.22 20-Oct K.HNAQGQGNGLR.Y "sp|P35813|PPM1A_HUMAN,tr|E9PL75|E9PL75_HUMAN,tr|E9PP44|E9PP44_HUMAN,tr|E9PKB5|E9PKB5_HUMAN,tr|E9PJN3|E9PJN3_HUMAN" 5 1150.5592 0.29 136699 2684 2 1150.555354 576.2869 Protein phosphatase 1A OS=Homo sapiens OX=9606 GN=PPM1A PE=1 SV=1 9.76 1213.3 - 452957 - - - -3.314 - 1.522 0.346 - 228.5 1 2 0 -0.0038 11 0 0 0 5.42E+06 1.86E+07 - - - 2.7316 0.998 221125_WJC_METTL3_EV_vs_WT_F10.02687.02687.2 8.03E-06 26-Sep R.SSGNAATSGNAATK.L "sp|P51003|PAPOA_HUMAN,tr|G3XAH6|G3XAH6_HUMAN,tr|H0YJL4|H0YJL4_HUMAN" 3 1235.5742 0.68 136702 2687 2 1235.569816 618.7944 Poly(A) polymerase alpha OS=Homo sapiens OX=9606 GN=PAPOLA PE=1 SV=4 8.47 1213.7 - 316309 - - - -3.5546 - 1.923 0.393 - 279.4 1 2 0 -0.0044 14 0 0 0 1.57E+06 2.31E+06 - - - 3.5832 0.915 221125_WJC_METTL3_EV_vs_WT_F10.02694.02694.2 0.00268 14-Aug V.NPNK[136.11]PATK[136.11].D "sp|Q06787|FMR1_HUMAN,tr|A0A087WY29|A0A087WY29_HUMAN,tr|R9WNI0|R9WNI0_HUMAN,tr|A8MQB8|A8MQB8_HUMAN,tr|A0A087WXI3|A0A087WXI3_HUMAN,tr|Q8IXW7|Q8IXW7_HUMAN,tr|G3V0J0|G3V0J0_HUMAN" 7 884.5051 1.85 136707 2694 2 884.502369 443.2598 Synaptic functional regulator FMR1 OS=Homo sapiens OX=9606 GN=FMR1 PE=1 SV=1 10 1214.5 - 2.17E+06 - - - -3.0492 - 1.734 0.373 - 282.5 1 1 0 -0.0027 8 0 0 0 3.53E+07 1.91E+07 - - - 3.4552 0.9997 221125_WJC_METTL3_EV_vs_WT_F10.02696.02696.2 0.00309 18-Oct K.DANQVHSTTR[166.11].R sp|Q7Z5L9|I2BP2_HUMAN 1 1137.5402 1.24 136709 2696 2 1137.537785 569.7774 Interferon regulatory factor 2-binding protein 2 OS=Homo sapiens OX=9606 GN=IRF2BP2 PE=1 SV=2 6.74 1214.7 - 1.19E+06 - - - -2.1397 - 2.19 0.491 - 417.5 1 2 0 -0.0024 10 0 0 0 3.73E+07 3.02E+07 - - - 4.8549 0.9986 221125_WJC_METTL3_EV_vs_WT_F10.02697.02697.2 0.00588 16-Sep K.HASLQNSQR[166.11].T sp|Q8TEQ6|GEMI5_HUMAN 1 1049.5242 0.9 136710 2697 2 1049.521473 525.7694 Gem-associated protein 5 OS=Homo sapiens OX=9606 GN=GEMIN5 PE=1 SV=3 9.76 1214.7 - 885910 - - - -2.5745 - 1.639 0.369 - 247.5 1 2 0 -0.0027 9 0 0 0 7.18E+06 7.99E+06 - - - 3.195 0.9998 221125_WJC_METTL3_EV_vs_WT_F10.02698.02698.2 0.00221 13/16 R.RPISSC[160.03]SQR.R sp|Q5T749|KPRP_HUMAN 1 1089.5349 999 136711 2698 2 1089.532688 545.7747 Keratinocyte proline-rich protein OS=Homo sapiens OX=9606 GN=KPRP PE=1 SV=1 10.35 1214.9 - 741297 - - - -2.0541 - 2.494 0.5 - 293.6 1 2 0 -0.0022 9 0 0 0 7.67E+07 0.00E+00 - - - 5.3772 0.9328 221125_WJC_METTL3_EV_vs_WT_F10.02701.02701.2 0.000197 14-Aug A.AAHTDHLR.D "sp|Q16891|MIC60_HUMAN,tr|B9A067|B9A067_HUMAN,tr|C9J406|C9J406_HUMAN,tr|H7C463|H7C463_HUMAN" 4 919.4624 1.22 136714 2701 2 919.459459 460.7385 MICOS complex subunit MIC60 OS=Homo sapiens OX=9606 GN=IMMT PE=1 SV=1 6.96 1215.2 - 293662 - - - -3.2127 - 1.642 0.456 - 193.8 1 1 0 -0.003 8 0 0 0 5.26E+06 4.32E+06 - - - 3.9037 0.9736 221125_WJC_METTL3_EV_vs_WT_F10.02703.02703.2 0.435 20-May K.VTPQSDGSSSK[136.11].V "sp|P34932|HSP74_HUMAN,tr|A0A087WYC1|A0A087WYC1_HUMAN" 2 1099.5237 0.21 136716 2703 2 1099.521631 550.7691 Heat shock 70 kDa protein 4 OS=Homo sapiens OX=9606 GN=HSPA4 PE=1 SV=4 5.81 1215.5 - 247581 - - - -1.8654 - 0.891 0.228 - 24.9 1 2 0 -0.0021 11 0 0 0 5.98E+05 2.81E+06 - - - 0.4122 0.9997 221125_WJC_METTL3_EV_vs_WT_F10.02708.02708.2 6.88E-05 18-Nov K.DANQVHSTTR.R sp|Q7Z5L9|I2BP2_HUMAN 1 1127.5319 1.09 136719 2708 2 1127.52912 564.7733 Interferon regulatory factor 2-binding protein 2 OS=Homo sapiens OX=9606 GN=IRF2BP2 PE=1 SV=2 6.74 1216.2 - 5.33E+06 - - - -2.509 - 2.312 0.542 - 559.2 1 2 0 -0.0028 10 0 0 0 3.72E+07 3.43E+07 - - - 5.3828 0.9994 221125_WJC_METTL3_EV_vs_WT_F10.02710.02710.2 0.203 14/16 K.KGQSEEIQK.K "sp|P83731|RL24_HUMAN,tr|C9JNW5|C9JNW5_HUMAN,tr|C9JXB8|C9JXB8_HUMAN" 3 1045.5404 1.41 136721 2710 2 1045.53818 523.7775 60S ribosomal protein L24 OS=Homo sapiens OX=9606 GN=RPL24 PE=1 SV=1 6.14 1216.3 - 2.40E+06 - - - -2.1118 - 2.437 0.303 - 793.2 1 2 0 -0.0022 9 0 0 0 4.92E+07 3.49E+07 - - - 3.8553 0.9728 221125_WJC_METTL3_EV_vs_WT_F10.02713.02713.2 0.038 14-Sep A.NQVHSTTR[166.11].R sp|Q7Z5L9|I2BP2_HUMAN 1 951.4762 1.53 136724 2713 2 951.474137 476.7454 Interferon regulatory factor 2-binding protein 2 OS=Homo sapiens OX=9606 GN=IRF2BP2 PE=1 SV=2 9.76 1216.5 - 1.46E+06 - - - -2.1283 - 1.692 0.471 - 530.8 1 1 0 -0.002 8 0 0 0 1.45E+07 9.44E+06 - - - 4.1053 0.9983 221125_WJC_METTL3_EV_vs_WT_F10.02714.02714.2 0.00368 18-Oct R.QAAAHTDHLR.D "sp|Q16891|MIC60_HUMAN,tr|B9A067|B9A067_HUMAN,tr|C9J406|C9J406_HUMAN,tr|H7C463|H7C463_HUMAN" 4 1118.5581 8.16 136725 2714 2 1118.55485 560.2863 MICOS complex subunit MIC60 OS=Homo sapiens OX=9606 GN=IMMT PE=1 SV=1 6.92 1216.6 - 1.34E+06 - - - -2.9091 - 2.286 0.253 - 599.2 1 2 0 -0.0033 10 0 0 0 1.92E+07 2.35E+06 - - - 3.2165 0.9987 221125_WJC_METTL3_EV_vs_WT_F10.02715.02715.3 0.000142 13/48 R.TPTGRPGGGGGTR.G sp|P11831|SRF_HUMAN 1 1169.5901 1.55 136726 2715 3 1169.587003 390.8707 Serum response factor OS=Homo sapiens OX=9606 GN=SRF PE=1 SV=1 12 1216.6 - 1.14E+06 - - - -2.6753 - 1.967 0.316 - 226.6 1 2 0 -0.0031 13 0 0 0 2.48E+07 1.60E+07 - - - 3.8964 0.9992 221125_WJC_METTL3_EV_vs_WT_F10.02716.02716.2 0.017 16-Oct K.HASLQNSQR.T sp|Q8TEQ6|GEMI5_HUMAN 1 1039.5159 0.98 136727 2716 2 1039.513944 520.7652 Gem-associated protein 5 OS=Homo sapiens OX=9606 GN=GEMIN5 PE=1 SV=3 9.76 1216.7 - 1.04E+06 - - - -1.8865 - 1.668 0.372 - 312.1 1 2 0 -0.002 9 0 0 0 8.42E+06 8.59E+06 - - - 3.2681 0.9907 221125_WJC_METTL3_EV_vs_WT_F10.02728.02728.3 0.00978 Nov-48 R.TPTGR[166.11]PGGGGGTR[166.11].G sp|P11831|SRF_HUMAN 1 1189.6067 1.57 136737 2728 3 1189.602659 397.5428 Serum response factor OS=Homo sapiens OX=9606 GN=SRF PE=1 SV=1 12 1218 - 2.07E+06 - - - -3.3734 - 2.123 0.205 - 110.9 1 2 0 -0.004 13 0 0 0 2.50E+07 1.59E+07 - - - 2.8656 0.9989 221125_WJC_METTL3_EV_vs_WT_F10.02730.02730.2 0.54 16-Sep R.RTGNAEIQK.Q sp|Q13835|PKP1_HUMAN 1 1015.5411 98.67 136739 2730 2 1015.53864 508.7778 Plakophilin-1 OS=Homo sapiens OX=9606 GN=PKP1 PE=1 SV=2 8.75 1218.2 - 1.15E+06 - - - -2.38 - 2.1 0.278 - 250.8 1 2 0 -0.0024 9 0 0 0 6.20E+06 6.29E+04 - - - 3.24 1 221125_WJC_METTL3_EV_vs_WT_F10.02733.02733.2 9.88E-09 14/24 K.QSSSSTTSQGGVK[136.11].R "sp|P18615|NELFE_HUMAN,tr|A2ABK4|A2ABK4_HUMAN,tr|A0A0A0MSN9|A0A0A0MSN9_HUMAN,tr|E9PD43|E9PD43_HUMAN,tr|A0A0A0MT02|A0A0A0MT02_HUMAN,tr|A0A0G2JI50|A0A0G2JI50_HUMAN" 6 1260.6037 0.51 136742 2733 2 1260.599795 631.3091 Negative elongation factor E OS=Homo sapiens OX=9606 GN=NELFE PE=1 SV=3 8.75 1218.6 - 375479 - - - -3.116 - 3.189 0.535 - 944.4 1 2 0 -0.0039 13 0 0 0 2.28E+06 4.45E+06 - - - 5.9677 0.9964 221125_WJC_METTL3_EV_vs_WT_F10.02738.02738.3 0.00697 Sep-36 K.DANQVHSTTR[166.11].R sp|Q7Z5L9|I2BP2_HUMAN 1 1137.5402 0.001 136745 2738 3 1137.536338 380.1873 Interferon regulatory factor 2-binding protein 2 OS=Homo sapiens OX=9606 GN=IRF2BP2 PE=1 SV=2 6.74 1219.2 - 7.01E+06 - - - -3.4117 - 1.586 0.329 - 129.9 1 2 0 -0.0039 10 0 0 0 0.00E+00 8.46E+07 - - - 3.5539 0.8259 221125_WJC_METTL3_EV_vs_WT_F10.02753.02753.2 0.0493 18-Sep R.LQEDTDK[136.11]ANK[136.11].Q sp|P12270|TPR_HUMAN 1 1176.5957 2.71 136758 2753 2 1176.592603 589.3051 Nucleoprotein TPR OS=Homo sapiens OX=9606 GN=TPR PE=1 SV=3 4.56 1220.7 - 902701 - - - -2.6585 - 1.548 0.107 - 252.1 1 2 1 -0.0031 10 0 0 0 1.78E+07 6.56E+06 - - - 1.05 0.9997 221125_WJC_METTL3_EV_vs_WT_F10.02765.02765.3 0.000106 13/44 K.VADSSKGPDEAK.L "sp|O60506|HNRPQ_HUMAN,tr|A0A7I2YQV8|A0A7I2YQV8_HUMAN,tr|A0A7I2YQN2|A0A7I2YQN2_HUMAN,tr|A0A7I2V5Q6|A0A7I2V5Q6_HUMAN,tr|A0A7I2V4Z0|A0A7I2V4Z0_HUMAN,tr|B7Z645|B7Z645_HUMAN,tr|A0A7I2V2F0|A0A7I2V2F0_HUMAN,tr|A0A7I2V2F2|A0A7I2V2F2_HUMAN,tr|A0A7I2V4J0|A0A7I2V4J0_HUMAN,tr|F6UXX1|F6UXX1_HUMAN,tr|A0A7I2V346|A0A7I2V346_HUMAN,tr|A0A7I2V309|A0A7I2V309_HUMAN" 12 1202.5779 1.28 136766 2765 3 1202.575496 401.8666 Heterogeneous nuclear ribonucleoprotein Q OS=Homo sapiens OX=9606 GN=SYNCRIP PE=1 SV=2 4.56 1222.3 - 1.41E+06 - - - -1.9957 - 2.531 0.47 - 207.7 1 2 1 -0.0024 12 0 0 0 7.39E+07 5.76E+07 - - - 6.3534 0.9978 221125_WJC_METTL3_EV_vs_WT_F10.02768.02768.3 0.000378 13/44 K.VADSSK[136.11]GPDEAK[136.11].L "sp|O60506|HNRPQ_HUMAN,tr|A0A7I2YQV8|A0A7I2YQV8_HUMAN,tr|A0A7I2YQN2|A0A7I2YQN2_HUMAN,tr|A0A7I2V5Q6|A0A7I2V5Q6_HUMAN,tr|A0A7I2V4Z0|A0A7I2V4Z0_HUMAN,tr|B7Z645|B7Z645_HUMAN,tr|A0A7I2V2F0|A0A7I2V2F0_HUMAN,tr|A0A7I2V2F2|A0A7I2V2F2_HUMAN,tr|A0A7I2V4J0|A0A7I2V4J0_HUMAN,tr|F6UXX1|F6UXX1_HUMAN,tr|A0A7I2V346|A0A7I2V346_HUMAN,tr|A0A7I2V309|A0A7I2V309_HUMAN" 12 1218.6063 1.28 136769 2768 3 1218.600947 407.2094 Heterogeneous nuclear ribonucleoprotein Q OS=Homo sapiens OX=9606 GN=SYNCRIP PE=1 SV=2 4.56 1222.7 - 1.14E+06 - - - -4.3894 - 2.701 0.42 - 225.5 1 2 1 -0.0053 12 0 0 0 7.39E+07 5.76E+07 - - - 5.9753 1 221125_WJC_METTL3_EV_vs_WT_F10.02771.02771.2 0.0002 13/22 K.NGSSSDSSVGEK.L "sp|Q9H4A3|WNK1_HUMAN,tr|F5GWT4|F5GWT4_HUMAN,tr|F6UYG0|F6UYG0_HUMAN" 3 1152.4895 2.07 136770 2771 2 1152.485194 577.252 Serine\threonine-protein kinase WNK1 OS=Homo sapiens OX=9606 GN=WNK1 PE=1 SV=2 4.37 1223.1 - 2.33E+06 - - - -3.7146 - 2.653 0.566 - 761.4 1 2 0 -0.0043 12 0 0 0 1.91E+07 9.20E+06 - - - 5.7873 0.9997 221125_WJC_METTL3_EV_vs_WT_F10.02772.02772.2 2.42E-07 13/22 K.NGSSSDSSVGEK[136.11].L "sp|Q9H4A3|WNK1_HUMAN,tr|F5GWT4|F5GWT4_HUMAN,tr|F6UYG0|F6UYG0_HUMAN" 3 1160.5037 2.07 136771 2772 2 1160.500962 581.2591 Serine\threonine-protein kinase WNK1 OS=Homo sapiens OX=9606 GN=WNK1 PE=1 SV=2 4.37 1223.2 - 1.30E+06 - - - -2.3378 - 2.741 0.489 - 775.1 1 2 0 -0.0027 12 0 0 0 1.91E+07 9.20E+06 - - - 5.305 0.8493 221125_WJC_METTL3_EV_vs_WT_F10.02775.02775.3 0.0506 Jul-44 K.DPSQESEENTAK.T "tr|A0A0A0MRQ6|A0A0A0MRQ6_HUMAN,tr|X6RDV4|X6RDV4_HUMAN" 2 1333.5634 1.37 136774 2775 3 1333.570889 445.5284 Solute carrier family 13 member 3 (Fragment) OS=Homo sapiens OX=9606 GN=SLC13A3 PE=1 SV=1 4 1223.5 - 1.62E+06 - - - 5.6398 - 1.347 0.265 - 52.7 4 2 0 0.0075 12 0 0 0 1.84E+08 1.34E+08 - - - 2.0394 0.9952 221125_WJC_METTL3_EV_vs_WT_F10.02776.02776.3 0.00633 Nov-36 K.NLNQDQQHGR.K sp|P04279|SEMG1_HUMAN 1 1208.5646 26.94 136775 2776 3 1208.560517 403.8622 Semenogelin-1 OS=Homo sapiens OX=9606 GN=SEMG1 PE=1 SV=2 6.74 1223.6 - 1.46E+06 - - - -3.4164 - 1.795 0.278 - 141.4 1 2 0 -0.0041 10 0 0 0 1.34E+07 4.99E+05 - - - 3.3468 0.9999 221125_WJC_METTL3_EV_vs_WT_F10.02782.02782.3 0.00117 15/44 R.GAAATTTTTEHR.F "sp|Q9H4A3|WNK1_HUMAN,tr|F5GWT4|F5GWT4_HUMAN,tr|F6UYG0|F6UYG0_HUMAN" 3 1215.5844 3.73 136779 2782 3 1215.58082 406.2021 Serine\threonine-protein kinase WNK1 OS=Homo sapiens OX=9606 GN=WNK1 PE=1 SV=2 6.75 1224.3 - 2.51E+06 - - - -2.927 - 2.83 0.431 - 361.9 1 2 0 -0.0036 12 0 0 0 9.29E+07 2.49E+07 - - - 6.2277 0.9999 221125_WJC_METTL3_EV_vs_WT_F10.02784.02784.3 1.53E-06 18/44 R.GAAATTTTTEHR[166.11].F "sp|Q9H4A3|WNK1_HUMAN,tr|F5GWT4|F5GWT4_HUMAN,tr|F6UYG0|F6UYG0_HUMAN" 3 1225.5926 3.75 136781 2784 3 1225.587842 409.5382 Serine\threonine-protein kinase WNK1 OS=Homo sapiens OX=9606 GN=WNK1 PE=1 SV=2 6.75 1224.4 - 1.60E+06 - - - -3.9214 - 3.226 0.565 - 558.4 1 2 0 -0.0048 12 0 0 0 8.93E+07 2.38E+07 - - - 8.0844 1 221125_WJC_METTL3_EV_vs_WT_F10.02786.02786.2 7.05E-08 14/26 K.AGGEGGSEEEGSDK.G "sp|P07197|NFM_HUMAN,tr|E7ESP9|E7ESP9_HUMAN" 2 1307.5113 3.44 136783 2786 2 1307.507695 654.7629 Neurofilament medium polypeptide OS=Homo sapiens OX=9606 GN=NEFM PE=1 SV=3 3.91 1224.6 - 1.03E+06 - - - -2.7824 - 2.957 0.623 - 692.8 1 2 0 -0.0036 14 0 0 0 9.50E+06 2.76E+06 - - - 6.362 0.9998 221125_WJC_METTL3_EV_vs_WT_F10.02787.02787.3 7.17E-05 15/48 R.VGQADDSTKPTNK.A "sp|P35658|NU214_HUMAN,tr|A0A0A0MSW3|A0A0A0MSW3_HUMAN,tr|E9PKD2|E9PKD2_HUMAN,tr|B7ZAV2|B7ZAV2_HUMAN,tr|A0A494C1F2|A0A494C1F2_HUMAN,tr|H0Y837|H0Y837_HUMAN" 6 1359.663 2.78 136784 2787 3 1359.659451 454.2283 Nuclear pore complex protein Nup214 OS=Homo sapiens OX=9606 GN=NUP214 PE=1 SV=2 5.93 1224.8 - 864202 - - - -2.6271 - 2.401 0.403 - 245.1 1 2 0 -0.0036 13 0 0 0 8.76E+06 3.15E+06 - - - 5.4068 0.9993 221125_WJC_METTL3_EV_vs_WT_F10.02788.02788.2 0.00948 20-Dec K.KTAEEPAASGR.L sp|Q9NQS7|INCE_HUMAN 1 1115.5571 2.54 136785 2788 2 1115.554181 558.7858 Inner centromere protein OS=Homo sapiens OX=9606 GN=INCENP PE=1 SV=3 6.14 1224.9 - 848710 - - - -2.6175 - 2.109 0.397 - 446.5 1 2 0 -0.0029 11 0 0 0 4.68E+06 1.85E+06 - - - 3.991 1 221125_WJC_METTL3_EV_vs_WT_F10.02792.02792.2 3.07E-07 14/26 K.AGGEGGSEEEGSDK[136.11].G "sp|P07197|NFM_HUMAN,tr|E7ESP9|E7ESP9_HUMAN" 2 1315.5255 3.44 136788 2792 2 1315.526084 658.77 Neurofilament medium polypeptide OS=Homo sapiens OX=9606 GN=NEFM PE=1 SV=3 3.91 1225.4 - 268706 - - - 0.4188 - 3.079 0.718 - 713.5 1 2 0 0.0006 14 0 0 0 9.50E+06 2.76E+06 - - - 7.1661 0.9996 221125_WJC_METTL3_EV_vs_WT_F10.02797.02797.2 5.38E-07 22-Dec R.GAAATTTTTEHR.F "sp|Q9H4A3|WNK1_HUMAN,tr|F5GWT4|F5GWT4_HUMAN,tr|F6UYG0|F6UYG0_HUMAN" 3 1215.5844 1.71 136791 2797 2 1215.581598 608.7995 Serine\threonine-protein kinase WNK1 OS=Homo sapiens OX=9606 GN=WNK1 PE=1 SV=2 6.75 1226 - 1.22E+06 - - - -2.287 - 2.766 0.397 - 595.8 1 2 0 -0.0028 12 0 0 0 6.36E+06 3.72E+06 - - - 4.6493 0.9999 221125_WJC_METTL3_EV_vs_WT_F10.02799.02799.3 8.36E-05 15/48 R.VGQADDSTK[136.11]PTNK[136.11].A "sp|P35658|NU214_HUMAN,tr|A0A0A0MSW3|A0A0A0MSW3_HUMAN,tr|E9PKD2|E9PKD2_HUMAN,tr|B7ZAV2|B7ZAV2_HUMAN,tr|A0A494C1F2|A0A494C1F2_HUMAN,tr|H0Y837|H0Y837_HUMAN" 6 1375.6914 2.65 136793 2799 3 1375.688396 459.5711 Nuclear pore complex protein Nup214 OS=Homo sapiens OX=9606 GN=NUP214 PE=1 SV=2 5.93 1226.3 - 681712 - - - -2.2003 - 2.348 0.489 - 276.5 1 2 0 -0.003 13 0 0 0 8.37E+06 3.15E+06 - - - 6.3053 0.9998 221125_WJC_METTL3_EV_vs_WT_F10.02800.02800.2 1.76E-05 22-Dec R.GAAATTTTTEHR[166.11].F "sp|Q9H4A3|WNK1_HUMAN,tr|F5GWT4|F5GWT4_HUMAN,tr|F6UYG0|F6UYG0_HUMAN" 3 1225.5926 1.71 136794 2800 2 1225.590282 613.8036 Serine\threonine-protein kinase WNK1 OS=Homo sapiens OX=9606 GN=WNK1 PE=1 SV=2 6.75 1226.4 - 652851 - - - -1.9305 - 2.684 0.534 - 621.4 1 2 0 -0.0024 12 0 0 0 6.36E+06 3.72E+06 - - - 5.5822 0.9986 221125_WJC_METTL3_EV_vs_WT_F10.02803.02803.2 0.00425 18-Jul K.QDAPSQSENK[136.11].K "sp|Q15003|CND2_HUMAN,tr|C9J470|C9J470_HUMAN,tr|E9PHA2|E9PHA2_HUMAN" 3 1110.5033 1.24 136797 2803 2 1110.500498 556.2589 Condensin complex subunit 2 OS=Homo sapiens OX=9606 GN=NCAPH PE=1 SV=3 4.37 1226.8 - 354417 - - - -2.5061 - 1.395 0.424 - 89.9 1 2 0 -0.0028 10 0 0 0 2.15E+06 1.73E+06 - - - 3.101 0.9903 221125_WJC_METTL3_EV_vs_WT_F10.02804.02804.2 4.92E-06 18-Sep A.AATTTTTEHR[166.11].F "sp|Q9H4A3|WNK1_HUMAN,tr|F5GWT4|F5GWT4_HUMAN,tr|F6UYG0|F6UYG0_HUMAN" 3 1097.5341 32.03 136798 2804 2 1097.532403 549.7743 Serine\threonine-protein kinase WNK1 OS=Homo sapiens OX=9606 GN=WNK1 PE=1 SV=2 6.79 1226.9 - 291938 - - - -1.5198 - 2.049 0.556 - 446.4 1 1 0 -0.0017 10 0 0 0 4.81E+07 1.50E+06 - - - 5.1494 0.9975 221125_WJC_METTL3_EV_vs_WT_F10.02813.02813.3 0.0507 Nov-32 R.LNK[136.11]HEENLK[136.11].T sp|P42766|RL35_HUMAN 1 1139.627 0.001 136805 2813 3 1139.624615 380.8829 60S ribosomal protein L35 OS=Homo sapiens OX=9606 GN=RPL35 PE=1 SV=2 6.76 1227.8 - 4.50E+06 - - - -2.0682 - 2.031 0.322 - 115.1 1 2 1 -0.0024 9 0 0 0 0.00E+00 3.46E+07 - - - 4.2647 1 221125_WJC_METTL3_EV_vs_WT_F10.02816.02816.2 1.82E-05 15/22 K.VADSSKGPDEAK.L "sp|O60506|HNRPQ_HUMAN,tr|A0A7I2YQV8|A0A7I2YQV8_HUMAN,tr|A0A7I2YQN2|A0A7I2YQN2_HUMAN,tr|A0A7I2V5Q6|A0A7I2V5Q6_HUMAN,tr|A0A7I2V4Z0|A0A7I2V4Z0_HUMAN,tr|B7Z645|B7Z645_HUMAN,tr|A0A7I2V2F0|A0A7I2V2F0_HUMAN,tr|A0A7I2V2F2|A0A7I2V2F2_HUMAN,tr|A0A7I2V4J0|A0A7I2V4J0_HUMAN,tr|F6UXX1|F6UXX1_HUMAN,tr|A0A7I2V346|A0A7I2V346_HUMAN,tr|A0A7I2V309|A0A7I2V309_HUMAN" 12 1202.5779 1.26 136808 2816 2 1202.575966 602.2962 Heterogeneous nuclear ribonucleoprotein Q OS=Homo sapiens OX=9606 GN=SYNCRIP PE=1 SV=2 4.56 1228.1 - 822304 - - - -1.6049 - 3.237 0.561 - 941.1 1 2 1 -0.0019 12 0 0 0 9.70E+06 7.70E+06 - - - 6.2746 0.9998 221125_WJC_METTL3_EV_vs_WT_F10.02817.02817.2 0.000792 16-Nov R.HVTAQQPSR[166.11].L "sp|O14979|HNRDL_HUMAN,tr|A0A087WUK2|A0A087WUK2_HUMAN" 2 1032.534 1.07 136809 2817 2 1032.532956 517.2743 Heterogeneous nuclear ribonucleoprotein D-like OS=Homo sapiens OX=9606 GN=HNRNPDL PE=1 SV=3 9.76 1228.3 - 607158 - - - -1.0218 - 1.781 0.531 - 426.8 1 2 0 -0.0011 9 0 0 0 2.51E+07 2.33E+07 - - - 4.6324 0.9849 221125_WJC_METTL3_EV_vs_WT_F10.02818.02818.2 0.00723 18-Sep A.AATTTTTEHR.F "sp|Q9H4A3|WNK1_HUMAN,tr|F5GWT4|F5GWT4_HUMAN,tr|F6UYG0|F6UYG0_HUMAN" 3 1087.5258 44.48 136810 2818 2 1087.524179 544.7702 Serine\threonine-protein kinase WNK1 OS=Homo sapiens OX=9606 GN=WNK1 PE=1 SV=2 6.79 1228.4 - 588090 - - - -1.4915 - 1.963 0.464 - 389.6 1 1 0 -0.0016 10 0 0 0 6.67E+07 1.50E+06 - - - 4.3503 0.9883 221125_WJC_METTL3_EV_vs_WT_F10.02827.02827.3 0.0135 Sep-40 K.LEDDAK[136.11]DNQQK[136.11].A "sp|Q14204|DYHC1_HUMAN,tr|A0A7P0T8N2|A0A7P0T8N2_HUMAN,tr|A0A7P0T9C4|A0A7P0T9C4_HUMAN,tr|A0A7P0TBJ7|A0A7P0TBJ7_HUMAN,tr|A0A7P0T9K2|A0A7P0T9K2_HUMAN,tr|A0A2R8Y706|A0A2R8Y706_HUMAN,tr|A0A7P0T916|A0A7P0T916_HUMAN,tr|A0A7P0TB75|A0A7P0TB75_HUMAN,tr|A0A7P0T8W5|A0A7P0T8W5_HUMAN,tr|A0A7P0TAF3|A0A7P0TAF3_HUMAN,tr|A0A7P0T9F1|A0A7P0T9F1_HUMAN,tr|A0A7P0TAW9|A0A7P0TAW9_HUMAN,tr|A0A7P0TA13|A0A7P0TA13_HUMAN,tr|A0A7P0T7V5|A0A7P0T7V5_HUMAN,tr|A0A7P0T9R4|A0A7P0T9R4_HUMAN,tr|A0A2R8Y5T0|A0A2R8Y5T0_HUMAN,tr|A0A2R8YFZ7|A0A2R8YFZ7_HUMAN,tr|A0A7P0T825|A0A7P0T825_HUMAN,tr|A0A2R8Y6H2|A0A2R8Y6H2_HUMAN,tr|A0A7P0TAM4|A0A7P0TAM4_HUMAN" 20 1318.6336 1.09 136817 2827 3 1318.629938 440.5518 Cytoplasmic dynein 1 heavy chain 1 OS=Homo sapiens OX=9606 GN=DYNC1H1 PE=1 SV=5 4.23 1229.4 - 1.88E+06 - - - -2.7566 - 1.724 0.302 - 90.2 1 2 1 -0.0036 11 0 0 0 2.14E+07 1.96E+07 - - - 3.4532 0.9972 221125_WJC_METTL3_EV_vs_WT_F10.02828.02828.3 0.00244 Nov-40 K.LEDDAKDNQQK.A "sp|Q14204|DYHC1_HUMAN,tr|A0A7P0T8N2|A0A7P0T8N2_HUMAN,tr|A0A7P0T9C4|A0A7P0T9C4_HUMAN,tr|A0A7P0TBJ7|A0A7P0TBJ7_HUMAN,tr|A0A7P0T9K2|A0A7P0T9K2_HUMAN,tr|A0A2R8Y706|A0A2R8Y706_HUMAN,tr|A0A7P0T916|A0A7P0T916_HUMAN,tr|A0A7P0TB75|A0A7P0TB75_HUMAN,tr|A0A7P0T8W5|A0A7P0T8W5_HUMAN,tr|A0A7P0TAF3|A0A7P0TAF3_HUMAN,tr|A0A7P0T9F1|A0A7P0T9F1_HUMAN,tr|A0A7P0TAW9|A0A7P0TAW9_HUMAN,tr|A0A7P0TA13|A0A7P0TA13_HUMAN,tr|A0A7P0T7V5|A0A7P0T7V5_HUMAN,tr|A0A7P0T9R4|A0A7P0T9R4_HUMAN,tr|A0A2R8Y5T0|A0A2R8Y5T0_HUMAN,tr|A0A2R8YFZ7|A0A2R8YFZ7_HUMAN,tr|A0A7P0T825|A0A7P0T825_HUMAN,tr|A0A2R8Y6H2|A0A2R8Y6H2_HUMAN,tr|A0A7P0TAM4|A0A7P0TAM4_HUMAN" 20 1302.6052 1.09 136818 2828 3 1302.601308 435.209 Cytoplasmic dynein 1 heavy chain 1 OS=Homo sapiens OX=9606 GN=DYNC1H1 PE=1 SV=5 4.23 1229.5 - 1.51E+06 - - - -2.9671 - 2.085 0.367 - 177.1 1 2 1 -0.0039 11 0 0 0 2.14E+07 1.96E+07 - - - 4.718 1 221125_WJC_METTL3_EV_vs_WT_F10.02830.02830.2 6.48E-06 14/24 K.AAGSPSSSDQDEK.L "sp|Q9Y520|PRC2C_HUMAN,tr|E7EPN9|E7EPN9_HUMAN" 2 1277.5372 1.69 136820 2830 2 1277.53443 639.7759 Protein PRRC2C OS=Homo sapiens OX=9606 GN=PRRC2C PE=1 SV=4 4.03 1229.8 - 521732 - - - -2.1322 - 2.672 0.654 - 786.1 1 2 0 -0.0027 13 0 0 0 7.50E+06 4.45E+06 - - - 6.393 1 221125_WJC_METTL3_EV_vs_WT_F10.02833.02833.2 1.89E-06 13/24 K.AAGSPSSSDQDEK[136.11].L "sp|Q9Y520|PRC2C_HUMAN,tr|E7EPN9|E7EPN9_HUMAN" 2 1285.5514 1.69 136823 2833 2 1285.547895 643.783 Protein PRRC2C OS=Homo sapiens OX=9606 GN=PRRC2C PE=1 SV=4 4.03 1230.2 - 387763 - - - -2.6907 - 2.496 0.675 - 647.4 1 2 0 -0.0035 13 0 0 0 7.50E+06 4.45E+06 - - - 6.373 0.9783 221125_WJC_METTL3_EV_vs_WT_F10.02836.02836.2 0.183 20-Sep K.TK[136.11]QGVAEAAGK[136.11].T "sp|P37840|SYUA_HUMAN,tr|A0A669KB41|A0A669KB41_HUMAN,tr|D6RA31|D6RA31_HUMAN,tr|A0A669KBH5|A0A669KBH5_HUMAN,tr|H6UYS7|H6UYS7_HUMAN,tr|E7EPV7|E7EPV7_HUMAN" 6 1074.6004 0.001 136826 2836 2 1074.598228 538.3075 Alpha-synuclein OS=Homo sapiens OX=9606 GN=SNCA PE=1 SV=1 8.26 1230.6 - 255962 - - - -2.0426 - 1.622 0.288 - 181.7 1 2 1 -0.0022 11 0 0 0 0.00E+00 1.44E+06 - - - 2.4759 0.9723 221125_WJC_METTL3_EV_vs_WT_F10.02838.02838.2 0.00577 20-Sep K.LEDDAK[136.11]DNQQK[136.11].A "sp|Q14204|DYHC1_HUMAN,tr|A0A7P0T8N2|A0A7P0T8N2_HUMAN,tr|A0A7P0T9C4|A0A7P0T9C4_HUMAN,tr|A0A7P0TBJ7|A0A7P0TBJ7_HUMAN,tr|A0A7P0T9K2|A0A7P0T9K2_HUMAN,tr|A0A2R8Y706|A0A2R8Y706_HUMAN,tr|A0A7P0T916|A0A7P0T916_HUMAN,tr|A0A7P0TB75|A0A7P0TB75_HUMAN,tr|A0A7P0T8W5|A0A7P0T8W5_HUMAN,tr|A0A7P0TAF3|A0A7P0TAF3_HUMAN,tr|A0A7P0T9F1|A0A7P0T9F1_HUMAN,tr|A0A7P0TAW9|A0A7P0TAW9_HUMAN,tr|A0A7P0TA13|A0A7P0TA13_HUMAN,tr|A0A7P0T7V5|A0A7P0T7V5_HUMAN,tr|A0A7P0T9R4|A0A7P0T9R4_HUMAN,tr|A0A2R8Y5T0|A0A2R8Y5T0_HUMAN,tr|A0A2R8YFZ7|A0A2R8YFZ7_HUMAN,tr|A0A7P0T825|A0A7P0T825_HUMAN,tr|A0A2R8Y6H2|A0A2R8Y6H2_HUMAN,tr|A0A7P0TAM4|A0A7P0TAM4_HUMAN" 20 1318.6336 1.06 136828 2838 2 1318.627593 660.3241 Cytoplasmic dynein 1 heavy chain 1 OS=Homo sapiens OX=9606 GN=DYNC1H1 PE=1 SV=5 4.23 1230.8 - 153654 - - - -4.535 - 2.19 0.411 - 238.3 1 2 1 -0.006 11 0 0 0 2.19E+06 2.07E+06 - - - 4.1954 0.9995 221125_WJC_METTL3_EV_vs_WT_F10.02841.02841.2 0.054 16-Dec R.HVTAQQPSR.L "sp|O14979|HNRDL_HUMAN,tr|A0A087WUK2|A0A087WUK2_HUMAN" 2 1022.5257 1.07 136829 2841 2 1022.523748 512.2701 Heterogeneous nuclear ribonucleoprotein D-like OS=Homo sapiens OX=9606 GN=HNRNPDL PE=1 SV=3 9.76 1231.2 - 1.99E+06 - - - -1.9491 - 2.035 0.387 - 481.7 1 2 0 -0.002 9 0 0 0 2.51E+07 2.33E+07 - - - 3.9543 0.9995 221125_WJC_METTL3_EV_vs_WT_F10.02843.02843.3 0.102 Nov-36 R.YVAQAHDK[136.11]PR[166.11].Y "sp|Q12931|TRAP1_HUMAN,tr|I3L0K7|I3L0K7_HUMAN,tr|I3L239|I3L239_HUMAN" 3 1201.6323 1.81 136831 2843 3 1201.628202 401.5514 "Heat shock protein 75 kDa, mitochondrial OS=Homo sapiens OX=9606 GN=TRAP1 PE=1 SV=3" 8.6 1231.4 - 6.08E+06 - - - -3.3896 - 2.286 0.374 - 156.8 1 2 0 -0.0041 10 0 0 0 6.54E+07 3.61E+07 - - - 5.1232 0.9996 221125_WJC_METTL3_EV_vs_WT_F10.02854.02854.2 3.21 13/16 K.RQEEEESVK.K sp|Q9Y5A9|YTHD2_HUMAN 1 1132.536 1.48 136840 2854 2 1132.533217 567.2753 YTH domain-containing family protein 2 OS=Homo sapiens OX=9606 GN=YTHDF2 PE=1 SV=2 4.49 1232.7 - 1.55E+06 - - - -2.4847 - 2.396 0.405 - 611.4 1 2 0 -0.0028 9 0 0 0 4.13E+07 2.79E+07 - - - 4.5594 0.9997 221125_WJC_METTL3_EV_vs_WT_F10.02857.02857.3 8.29E-05 Dec-36 R.ATETDK[136.11]EPQR[166.11].L "sp|Q12756|KIF1A_HUMAN,tr|A0A3B3ITW6|A0A3B3ITW6_HUMAN,tr|A0A3B3ITF7|A0A3B3ITF7_HUMAN,tr|A0A3B3ITE5|A0A3B3ITE5_HUMAN,tr|H7C3Y8|H7C3Y8_HUMAN,tr|A0A3B3IUA1|A0A3B3IUA1_HUMAN,tr|A0A3B3IT28|A0A3B3IT28_HUMAN,tr|A0A3F2YNW9|A0A3F2YNW9_HUMAN,tr|A0A3B3IU40|A0A3B3IU40_HUMAN,tr|A0A3B3ITK3|A0A3B3ITK3_HUMAN" 10 1191.585 3.79 136843 2857 3 1191.582646 398.2023 Kinesin-like protein KIF1A OS=Homo sapiens OX=9606 GN=KIF1A PE=1 SV=2 4.68 1233 - 761134 - - - -2.0175 - 2.136 0.495 - 234.3 1 2 1 -0.0024 10 0 0 0 2.23E+07 5.88E+06 - - - 6.2745 0.9888 221125_WJC_METTL3_EV_vs_WT_F10.02861.02861.2 0.00432 20-Jul K.LEDDAKDNQQK.A "sp|Q14204|DYHC1_HUMAN,tr|A0A7P0T8N2|A0A7P0T8N2_HUMAN,tr|A0A7P0T9C4|A0A7P0T9C4_HUMAN,tr|A0A7P0TBJ7|A0A7P0TBJ7_HUMAN,tr|A0A7P0T9K2|A0A7P0T9K2_HUMAN,tr|A0A2R8Y706|A0A2R8Y706_HUMAN,tr|A0A7P0T916|A0A7P0T916_HUMAN,tr|A0A7P0TB75|A0A7P0TB75_HUMAN,tr|A0A7P0T8W5|A0A7P0T8W5_HUMAN,tr|A0A7P0TAF3|A0A7P0TAF3_HUMAN,tr|A0A7P0T9F1|A0A7P0T9F1_HUMAN,tr|A0A7P0TAW9|A0A7P0TAW9_HUMAN,tr|A0A7P0TA13|A0A7P0TA13_HUMAN,tr|A0A7P0T7V5|A0A7P0T7V5_HUMAN,tr|A0A7P0T9R4|A0A7P0T9R4_HUMAN,tr|A0A2R8Y5T0|A0A2R8Y5T0_HUMAN,tr|A0A2R8YFZ7|A0A2R8YFZ7_HUMAN,tr|A0A7P0T825|A0A7P0T825_HUMAN,tr|A0A2R8Y6H2|A0A2R8Y6H2_HUMAN,tr|A0A7P0TAM4|A0A7P0TAM4_HUMAN" 20 1302.6052 1.06 136847 2861 2 1302.601697 652.3099 Cytoplasmic dynein 1 heavy chain 1 OS=Homo sapiens OX=9606 GN=DYNC1H1 PE=1 SV=5 4.23 1233.5 - 247874 - - - -2.6685 - 1.472 0.479 - 144.1 1 2 1 -0.0035 11 0 0 0 2.19E+06 2.07E+06 - - - 3.6237 0.9999 221125_WJC_METTL3_EV_vs_WT_F10.02862.02862.2 2.08E-05 18-Sep R.SNNADC[160.03]QAER.E "sp|Q9NNX1|TUFT1_HUMAN,tr|A6PVU8|A6PVU8_HUMAN" 2 1163.4625 8.03 136848 2862 2 1163.461775 582.7386 Tuftelin OS=Homo sapiens OX=9606 GN=TUFT1 PE=1 SV=1 4.37 1233.6 - 192842 - - - -0.6653 - 1.979 0.609 - 297.8 1 2 0 -0.0008 10 0 0 0 1.41E+06 1.75E+05 - - - 5.4442 0.934 221125_WJC_METTL3_EV_vs_WT_F10.02869.02869.2 0.118 16-Jun R.NTDVEKPSK.E "sp|Q96AV8|E2F7_HUMAN,tr|F8VSE7|F8VSE7_HUMAN" 2 1016.5138 0.07 136853 2869 2 1016.507995 509.2642 Transcription factor E2F7 OS=Homo sapiens OX=9606 GN=E2F7 PE=1 SV=3 6.07 1234.5 - 170719 - - - -5.7491 - 1.283 0.267 - 132.8 1 2 0 -0.0058 9 0 0 0 1.41E+06 1.99E+07 - - - 1.7322 0.9997 221125_WJC_METTL3_EV_vs_WT_F10.02875.02875.3 0.015 14/40 K.MENDESAKEEK.S "sp|Q9P2K5|MYEF2_HUMAN,tr|A0A0A0MR39|A0A0A0MR39_HUMAN,tr|A0A087WUT0|A0A087WUT0_HUMAN,tr|A0A087WWC8|A0A087WWC8_HUMAN,tr|A0A0A0MQW0|A0A0A0MQW0_HUMAN" 5 1308.5504 1.27 136857 2875 3 1308.547477 437.1907 Myelin expression factor 2 OS=Homo sapiens OX=9606 GN=MYEF2 PE=1 SV=3 4.25 1235.2 - 1.71E+06 - - - -2.204 - 2.836 0.446 - 292 1 2 1 -0.0029 11 0 0 0 3.57E+07 2.80E+07 - - - 6.4729 0.9777 221125_WJC_METTL3_EV_vs_WT_F10.02878.02878.2 0.00981 16-Oct K.EK[136.11]DSELNQK[136.11].R "sp|Q14683|SMC1A_HUMAN,tr|G8JLG1|G8JLG1_HUMAN" 2 1105.5586 1.44 136860 2878 2 1105.556359 553.7866 Structural maintenance of chromosomes protein 1A OS=Homo sapiens OX=9606 GN=SMC1A PE=1 SV=2 4.68 1235.6 - 625508 - - - -2.0433 - 1.78 0.236 - 280.5 1 2 1 -0.0023 9 0 0 0 1.35E+07 9.36E+06 - - - 2.4516 0.992 221125_WJC_METTL3_EV_vs_WT_F10.02883.02883.2 0.0421 20-Oct K.MENDESAKEEK.S "sp|Q9P2K5|MYEF2_HUMAN,tr|A0A0A0MR39|A0A0A0MR39_HUMAN,tr|A0A087WUT0|A0A087WUT0_HUMAN,tr|A0A087WWC8|A0A087WWC8_HUMAN,tr|A0A0A0MQW0|A0A0A0MQW0_HUMAN" 5 1308.5504 1.35 136865 2883 2 1308.546142 655.2825 Myelin expression factor 2 OS=Homo sapiens OX=9606 GN=MYEF2 PE=1 SV=3 4.25 1236.2 - 121392 - - - -3.2242 - 2.196 0.471 - 366.2 1 2 1 -0.0042 11 0 0 0 3.15E+06 2.33E+06 - - - 4.6465 0.9974 221125_WJC_METTL3_EV_vs_WT_F10.02884.02884.2 0.00527 16-Jul R.STNLSQHQR[166.11].T sp|Q9UJN7|ZN391_HUMAN 1 1079.5347 0.73 136866 2884 2 1079.53452 540.7746 Zinc finger protein 391 OS=Homo sapiens OX=9606 GN=ZNF391 PE=2 SV=2 9.49 1236.3 - 243564 - - - -0.2038 - 1.501 0.186 - 253.4 1 2 0 -0.0002 9 0 0 0 3.24E+05 4.47E+05 - - - 1.5897 0.993 221125_WJC_METTL3_EV_vs_WT_F10.02894.02894.2 0.003 20-Oct K.MENDESAK[136.11]EEK[136.11].S "sp|Q9P2K5|MYEF2_HUMAN,tr|A0A0A0MR39|A0A0A0MR39_HUMAN,tr|A0A087WUT0|A0A087WUT0_HUMAN,tr|A0A087WWC8|A0A087WWC8_HUMAN,tr|A0A0A0MQW0|A0A0A0MQW0_HUMAN" 5 1324.5788 1.35 136874 2894 2 1324.574029 663.2967 Myelin expression factor 2 OS=Homo sapiens OX=9606 GN=MYEF2 PE=1 SV=3 4.25 1237.6 - 327523 - - - -3.5725 - 2.308 0.555 - 329.5 1 2 1 -0.0047 11 0 0 0 3.15E+06 2.33E+06 - - - 5.4014 0.9991 221125_WJC_METTL3_EV_vs_WT_F10.02896.02896.2 0.0814 16-Sep R.KSSTPEEVK.K "sp|P23528|COF1_HUMAN,tr|E9PP50|E9PP50_HUMAN,tr|G3V1A4|G3V1A4_HUMAN,tr|E9PQB7|E9PQB7_HUMAN,tr|E9PK25|E9PK25_HUMAN,tr|E9PLJ3|E9PLJ3_HUMAN,tr|E9PS23|E9PS23_HUMAN" 7 1003.5186 1.3 136876 2896 2 1003.517917 502.7666 Cofilin-1 OS=Homo sapiens OX=9606 GN=CFL1 PE=1 SV=3 6.14 1237.8 - 284852 - - - -0.6706 - 1.827 0.23 - 245.4 1 2 0 -0.0007 9 0 0 0 5.05E+07 3.87E+07 - - - 2.4831 0.977 221125_WJC_METTL3_EV_vs_WT_F10.02903.02903.2 8.22E-06 22-Nov K.QSHGAAPC[160.03]SGGS.Q "sp|Q86SG5|S1A7A_HUMAN,sp|P31151|S10A7_HUMAN" 2 1114.4462 - 136881 2903 2 1114.443334 558.2304 Protein S100-A7A OS=Homo sapiens OX=9606 GN=S100A7A PE=1 SV=3 6.73 1238.7 - 7.59E+06 - - - -2.5457 - 2.028 0.533 - 376.1 1 1 0 -0.0028 12 0 0 0 - - - - - 4.8372 0.8277 221125_WJC_METTL3_EV_vs_WT_F10.02906.02906.3 1.03E-05 14/48 L.NSSASEPAK[136.11]EPAK[136.11].K "sp|Q86U44|MTA70_HUMAN,tr|F5H6D8|F5H6D8_HUMAN,tr|H0YFV6|H0YFV6_HUMAN,tr|B4DTN4|B4DTN4_HUMAN" 4 1330.67 0.05 136883 2906 3 1330.66451 444.5639 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 6.14 1238.9 - 1.18E+06 - - - -4.0949 - 2.219 0.464 - 239.5 1 1 1 -0.0054 13 0 0 0 6.32E+05 1.34E+07 - - - 5.8727 0.999 221125_WJC_METTL3_EV_vs_WT_F10.02907.02907.3 4.84E-06 13/40 K.AKAPQQEEGPK.G "sp|P35269|T2FA_HUMAN,tr|M0R0R9|M0R0R9_HUMAN,tr|M0QXD6|M0QXD6_HUMAN" 3 1181.6041 0.83 136884 2907 3 1181.600833 394.8753 General transcription factor IIF subunit 1 OS=Homo sapiens OX=9606 GN=GTF2F1 PE=1 SV=2 6.19 1239 - 1.01E+06 - - - -2.7234 - 2.403 0.406 - 258.3 1 2 1 -0.0032 11 0 0 0 1.46E+07 1.77E+07 - - - 5.5562 0.9998 221125_WJC_METTL3_EV_vs_WT_F10.02908.02908.2 0.000185 16-Dec R.K[136.11]SSTPEEVK[136.11].K "sp|P23528|COF1_HUMAN,tr|E9PP50|E9PP50_HUMAN,tr|G3V1A4|G3V1A4_HUMAN,tr|E9PQB7|E9PQB7_HUMAN,tr|E9PK25|E9PK25_HUMAN,tr|E9PLJ3|E9PLJ3_HUMAN,tr|E9PS23|E9PS23_HUMAN" 7 1019.547 1.31 136885 2908 2 1019.545583 510.7808 Cofilin-1 OS=Homo sapiens OX=9606 GN=CFL1 PE=1 SV=3 6.14 1239.1 - 885897 - - - -1.38 - 2.334 0.458 - 399.6 1 2 0 -0.0014 9 0 0 0 5.05E+07 3.86E+07 - - - 4.8755 1 221125_WJC_METTL3_EV_vs_WT_F10.02912.02912.2 7.66E-08 24-Nov R.AESTANAGQSDNR.S "sp|O75179|ANR17_HUMAN,tr|H0YM23|H0YM23_HUMAN,tr|A0A1W2PQ15|A0A1W2PQ15_HUMAN" 3 1319.5702 3.25 136889 2912 2 1319.565506 660.7924 Ankyrin repeat domain-containing protein 17 OS=Homo sapiens OX=9606 GN=ANKRD17 PE=1 SV=3 4.37 1239.6 - 133237 - - - -3.5459 - 2.372 0.622 - 427.9 1 2 0 -0.0047 13 0 0 0 2.41E+07 7.44E+06 - - - 5.8504 0.9984 221125_WJC_METTL3_EV_vs_WT_F10.02918.02918.2 0.00531 14-Jul R.SYSPAHNR.E "sp|Q9Y2W1|TR150_HUMAN,tr|A0A3B3ITZ9|A0A3B3ITZ9_HUMAN" 2 930.4308 2.51 136892 2918 2 930.428025 466.2227 Thyroid hormone receptor-associated protein 3 OS=Homo sapiens OX=9606 GN=THRAP3 PE=1 SV=2 8.49 1240.3 - 910380 - - - -2.9588 - 1.496 0.414 - 186.7 1 2 0 -0.0028 8 0 0 0 2.16E+07 8.62E+06 - - - 3.3128 0.9993 221125_WJC_METTL3_EV_vs_WT_F10.02920.02920.2 0.000459 14-Aug R.SYSPAHNR[166.11].E "sp|Q9Y2W1|TR150_HUMAN,tr|A0A3B3ITZ9|A0A3B3ITZ9_HUMAN" 2 940.439 2.44 136894 2920 2 940.436919 471.2268 Thyroid hormone receptor-associated protein 3 OS=Homo sapiens OX=9606 GN=THRAP3 PE=1 SV=2 8.49 1240.6 - 497715 - - - -2.2638 - 1.546 0.464 - 278.2 1 2 0 -0.0021 8 0 0 0 2.17E+07 8.90E+06 - - - 3.7814 0.9998 221125_WJC_METTL3_EV_vs_WT_F10.02925.02925.2 0.000562 24-Dec R.AESTANAGQSDNR[166.11].S "sp|O75179|ANR17_HUMAN,tr|H0YM23|H0YM23_HUMAN,tr|A0A1W2PQ15|A0A1W2PQ15_HUMAN" 3 1329.5785 3.28 136897 2925 2 1329.575319 665.7965 Ankyrin repeat domain-containing protein 17 OS=Homo sapiens OX=9606 GN=ANKRD17 PE=1 SV=3 4.37 1241.3 - 580636 - - - -2.3586 - 2.552 0.567 - 615.6 1 2 0 -0.0031 13 0 0 0 2.44E+07 7.44E+06 - - - 5.6324 0.9991 221125_WJC_METTL3_EV_vs_WT_F10.02932.02932.3 0.00575 Aug-40 K.EQK[136.11]PNTVGC[160.03]GK[136.11].E "sp|Q92615|LAR4B_HUMAN,tr|A0A087X183|A0A087X183_HUMAN,tr|H0Y4V9|H0Y4V9_HUMAN" 3 1232.6154 1.14 136902 2932 3 1232.612506 411.8791 La-related protein 4B OS=Homo sapiens OX=9606 GN=LARP4B PE=1 SV=3 8.29 1242.1 - 2.56E+06 - - - -2.3649 - 1.729 0.353 - 74.8 1 2 0 -0.0029 11 0 0 0 6.53E+07 5.73E+07 - - - 4.0303 0.9673 221125_WJC_METTL3_EV_vs_WT_F10.02935.02935.2 3.42 16-Jun R.KISSPTGSK.D "sp|Q99623|PHB2_HUMAN,tr|A0A7I2V5F0|A0A7I2V5F0_HUMAN,tr|F5GWA7|F5GWA7_HUMAN,tr|J3KPX7|J3KPX7_HUMAN,tr|F5GY37|F5GY37_HUMAN" 5 903.5025 1.25 136905 2935 2 903.501341 452.7585 Prohibitin-2 OS=Homo sapiens OX=9606 GN=PHB2 PE=1 SV=2 10 1242.5 - 276636 - - - -1.3337 - 1.182 0.072 - 108.1 1 2 0 -0.0012 9 0 0 0 4.02E+06 3.20E+06 - - - 0.0562 0.9995 221125_WJC_METTL3_EV_vs_WT_F10.02941.02941.2 0.0137 20-Sep K.EQK[136.11]PNTVGC[160.03]GK[136.11].E "sp|Q92615|LAR4B_HUMAN,tr|A0A087X183|A0A087X183_HUMAN,tr|H0Y4V9|H0Y4V9_HUMAN" 3 1232.6154 1.26 136909 2941 2 1232.61276 617.315 La-related protein 4B OS=Homo sapiens OX=9606 GN=LARP4B PE=1 SV=3 8.29 1243.3 - 440581 - - - -2.1588 - 1.913 0.425 - 177.2 1 2 0 -0.0027 11 0 0 0 6.17E+06 4.91E+06 - - - 3.934 0.9634 221125_WJC_METTL3_EV_vs_WT_F10.02942.02942.2 0.0401 14-Jul R.SKGQESFK.K "sp|P06748|NPM_HUMAN,tr|E5RI98|E5RI98_HUMAN,tr|A0A7I2V5S2|A0A7I2V5S2_HUMAN" 3 909.4556 0.78 136910 2942 2 909.454478 455.7351 Nucleophosmin OS=Homo sapiens OX=9606 GN=NPM1 PE=1 SV=2 8.31 1243.4 - 314701 - - - -1.2293 - 1.162 0.286 - 123.3 1 2 1 -0.0011 8 0 0 0 4.33E+06 5.56E+06 - - - 1.6059 0.9971 221125_WJC_METTL3_EV_vs_WT_F10.02944.02944.2 0.00564 24-Jul K.DQEGGASSSQAEK.E sp|Q15911|ZFHX3_HUMAN 1 1292.5481 2.63 136912 2944 2 1292.542554 647.2813 Zinc finger homeobox protein 3 OS=Homo sapiens OX=9606 GN=ZFHX3 PE=1 SV=2 4.14 1243.7 - 59791.9 - - - -4.2544 - 1.572 0.481 - 124.6 1 2 0 -0.0055 13 0 0 0 6.37E+05 2.42E+05 - - - 3.7529 0.985 221125_WJC_METTL3_EV_vs_WT_F10.02948.02948.2 0.0118 14-Jul R.SK[136.11]GQESFK[136.11].K "sp|P06748|NPM_HUMAN,tr|E5RI98|E5RI98_HUMAN,tr|A0A7I2V5S2|A0A7I2V5S2_HUMAN" 3 925.484 0.78 136914 2948 2 925.482036 463.7493 Nucleophosmin OS=Homo sapiens OX=9606 GN=NPM1 PE=1 SV=2 8.31 1244.2 - 698879 - - - -2.1178 - 1.517 0.349 - 115.6 1 2 1 -0.002 8 0 0 0 4.33E+06 5.56E+06 - - - 2.875 0.9874 221125_WJC_METTL3_EV_vs_WT_F10.02950.02950.2 0.000103 20-Aug S.SSGQEVQSSAK.E "sp|P35527|K1C9_HUMAN,tr|K7EQQ3|K7EQQ3_HUMAN" 2 1106.5204 91.07 136916 2950 2 1106.520302 554.2675 "Keratin, type I cytoskeletal 9 OS=Homo sapiens OX=9606 GN=KRT9 PE=1 SV=3" 5.72 1244.4 - 459445 - - - -0.0714 - 1.789 0.457 - 265.1 1 1 0 -0.0001 11 0 0 0 5.19E+06 5.70E+04 - - - 3.9899 0.9874 221125_WJC_METTL3_EV_vs_WT_F10.02952.02952.3 0.34 Sep-44 K.LEDGNKEQEQTK.Q "sp|Q13439|GOGA4_HUMAN,tr|H0Y6I0|H0Y6I0_HUMAN,tr|C9JHJ5|C9JHJ5_HUMAN" 3 1417.6685 1.87 136918 2952 3 1417.666369 473.5634 Golgin subfamily A member 4 OS=Homo sapiens OX=9606 GN=GOLGA4 PE=1 SV=1 4.41 1244.7 - 446144 - - - -1.5046 - 1.808 0.234 - 98.5 1 2 1 -0.0021 12 0 0 0 4.99E+06 2.66E+06 - - - 2.7898 0.9996 221125_WJC_METTL3_EV_vs_WT_F10.02954.02954.2 1.05E-05 20-Oct R.NADC[160.03]SSGPGQR[166.11].V "sp|Q9BSD7|NTPCR_HUMAN,tr|Q5TDF0|Q5TDF0_HUMAN" 2 1157.4759 1.18 136920 2954 2 1157.473444 579.7452 Cancer-related nucleoside-triphosphatase OS=Homo sapiens OX=9606 GN=NTPCR PE=1 SV=1 5.83 1244.9 - 183081 - - - -2.1253 - 2.006 0.456 - 460.7 1 2 0 -0.0025 11 0 0 0 9.03E+07 7.63E+07 - - - 4.2915 0.9999 221125_WJC_METTL3_EV_vs_WT_F10.02960.02960.2 1.05E-07 20-Oct R.NADC[160.03]SSGPGQR.V "sp|Q9BSD7|NTPCR_HUMAN,tr|Q5TDF0|Q5TDF0_HUMAN" 2 1147.4676 1.18 136924 2960 2 1147.466105 574.7411 Cancer-related nucleoside-triphosphatase OS=Homo sapiens OX=9606 GN=NTPCR PE=1 SV=1 5.83 1245.8 - 594570 - - - -1.3325 - 1.952 0.656 - 469.4 1 2 0 -0.0015 11 0 0 0 9.03E+07 7.63E+07 - - - 5.6951 0.9986 221125_WJC_METTL3_EV_vs_WT_F10.02961.02961.3 0.000169 Oct-44 K.LEDGNK[136.11]EQEQTK[136.11].Q "sp|Q13439|GOGA4_HUMAN,tr|H0Y6I0|H0Y6I0_HUMAN,tr|C9JHJ5|C9JHJ5_HUMAN" 3 1433.6969 1.87 136925 2961 3 1433.696079 478.9062 Golgin subfamily A member 4 OS=Homo sapiens OX=9606 GN=GOLGA4 PE=1 SV=1 4.41 1245.9 - 512365 - - - -0.574 - 1.775 0.364 - 115.5 1 2 1 -0.0008 12 0 0 0 4.99E+06 2.66E+06 - - - 4.1885 1 221125_WJC_METTL3_EV_vs_WT_F10.02962.02962.2 3.25E-07 16-Nov K.NHAC[160.03]EMC[160.03]GK[136.11].A "sp|Q14119|VEZF1_HUMAN,sp|P56270|MAZ_HUMAN,tr|J3QSH4|J3QSH4_HUMAN,tr|I3L2Z5|I3L2Z5_HUMAN,tr|A0A087WWR2|A0A087WWR2_HUMAN" 5 1113.4245 1.02 136926 2962 2 1113.423633 557.7195 Vascular endothelial zinc finger 1 OS=Homo sapiens OX=9606 GN=VEZF1 PE=1 SV=2 6.73 1246 - 366347 - - - -0.7957 - 2.42 0.671 - 612 1 2 0 -0.0009 9 0 0 0 3.16E+06 3.11E+06 - - - 6.5535 0.998 221125_WJC_METTL3_EV_vs_WT_F10.02963.02963.2 0.0529 16-Jul R.SSR[166.11]PAQPPR[166.11].L "sp|Q8WWB7|GLMP_HUMAN,tr|X6R6A3|X6R6A3_HUMAN,tr|A0A087X0W3|A0A087X0W3_HUMAN,tr|A0A087WV34|A0A087WV34_HUMAN" 4 1014.5474 0.06 136927 2963 2 1014.54571 508.281 Glycosylated lysosomal membrane protein OS=Homo sapiens OX=9606 GN=GLMP PE=1 SV=1 12 1246.2 - 253471 - - - -1.6332 - 1.376 0.305 - 118.7 1 2 0 -0.0017 9 0 0 0 1.24E+05 2.01E+06 - - - 2.2166 0.9993 221125_WJC_METTL3_EV_vs_WT_F10.02964.02964.2 0.00289 14-Jul R.DQINSDHR.T sp|Q12874|SF3A3_HUMAN 1 983.4421 3.93 136928 2964 2 983.4411 492.7283 Splicing factor 3A subunit 3 OS=Homo sapiens OX=9606 GN=SF3A3 PE=1 SV=1 5.21 1246.3 - 239704 - - - -0.9873 - 1.58 0.337 - 270.6 1 2 0 -0.001 8 0 0 0 1.92E+07 4.89E+06 - - - 2.9093 1 221125_WJC_METTL3_EV_vs_WT_F10.02970.02970.2 1.04E-08 14/24 K.AAEEQGDDQDSEK.S "sp|Q1KMD3|HNRL2_HUMAN,tr|H3BQZ7|H3BQZ7_HUMAN" 2 1420.559 1.56 136933 2970 2 1420.557497 711.2868 Heterogeneous nuclear ribonucleoprotein U-like protein 2 OS=Homo sapiens OX=9606 GN=HNRNPUL2 PE=1 SV=1 3.71 1247 - 441046 - - - -1.0658 - 2.923 0.628 - 746.6 1 2 0 -0.0015 13 0 0 0 8.12E+06 5.22E+06 - - - 6.4318 0.9952 221125_WJC_METTL3_EV_vs_WT_F10.02974.02974.2 0.0171 14-Aug R.DQINSDHR[166.11].T sp|Q12874|SF3A3_HUMAN 1 993.4503 3.97 136937 2974 2 993.453567 497.7324 Splicing factor 3A subunit 3 OS=Homo sapiens OX=9606 GN=SF3A3 PE=1 SV=1 5.21 1247.5 - 302348 - - - 3.2473 - 1.424 0.321 - 358.9 1 2 0 0.0032 8 0 0 0 1.91E+07 4.80E+06 - - - 2.4769 1 221125_WJC_METTL3_EV_vs_WT_F10.02975.02975.2 2.33E-09 13/24 K.AAEEQGDDQDSEK[136.11].S "sp|Q1KMD3|HNRL2_HUMAN,tr|H3BQZ7|H3BQZ7_HUMAN" 2 1428.5732 1.56 136938 2975 2 1428.57163 715.2939 Heterogeneous nuclear ribonucleoprotein U-like protein 2 OS=Homo sapiens OX=9606 GN=HNRNPUL2 PE=1 SV=1 3.71 1247.6 - 259694 - - - -1.1067 - 2.836 0.725 - 618 1 2 0 -0.0016 13 0 0 0 8.12E+06 5.22E+06 - - - 7.0707 1 221125_WJC_METTL3_EV_vs_WT_F10.02976.02976.2 6.43E-09 15/28 G.VGTESGSESGSSNAK[136.11].E "sp|Q9Y2Q9|RT28_HUMAN,tr|E5RFT8|E5RFT8_HUMAN,tr|H7C5V3|H7C5V3_HUMAN" 3 1403.6256 1.49 136939 2976 2 1403.626756 702.8201 "28S ribosomal protein S28, mitochondrial OS=Homo sapiens OX=9606 GN=MRPS28 PE=1 SV=1" 4.53 1247.8 - 156415 - - - 0.8371 - 3.413 0.674 - 774 1 1 0 0.0012 15 0 0 0 8.92E+06 5.97E+06 - - - 7.0369 1 221125_WJC_METTL3_EV_vs_WT_F10.02977.02977.2 3.29E-06 16/28 G.VGTESGSESGSSNAK.E "sp|Q9Y2Q9|RT28_HUMAN,tr|E5RFT8|E5RFT8_HUMAN,tr|H7C5V3|H7C5V3_HUMAN" 3 1395.6114 1.23 136940 2977 2 1395.610848 698.813 "28S ribosomal protein S28, mitochondrial OS=Homo sapiens OX=9606 GN=MRPS28 PE=1 SV=1" 4.53 1247.9 - 146404 - - - -0.3819 - 3.522 0.682 - 940.2 1 1 0 -0.0005 15 0 0 0 7.33E+06 5.97E+06 - - - 7.1735 0.9998 221125_WJC_METTL3_EV_vs_WT_F10.02983.02983.2 0.00135 16-Aug K.NHAC[160.03]EMC[160.03]GK.A "sp|Q14119|VEZF1_HUMAN,sp|P56270|MAZ_HUMAN,tr|J3QSH4|J3QSH4_HUMAN,tr|I3L2Z5|I3L2Z5_HUMAN,tr|A0A087WWR2|A0A087WWR2_HUMAN" 5 1105.4103 1.02 136944 2983 2 1105.410242 553.7124 Vascular endothelial zinc finger 1 OS=Homo sapiens OX=9606 GN=VEZF1 PE=1 SV=2 6.73 1248.6 - 411878 - - - -0.0697 - 1.69 0.521 - 227.8 1 2 0 -0.0001 9 0 0 0 3.16E+06 3.11E+06 - - - 4.4071 0.9464 221125_WJC_METTL3_EV_vs_WT_F10.02987.02987.2 0.0593 20-Aug T.KAQEEQTSSSK[136.11].G sp|Q4G0P3|HYDIN_HUMAN 1 1229.5979 - 136948 2987 2 1229.599017 615.8062 Hydrocephalus-inducing protein homolog OS=Homo sapiens OX=9606 GN=HYDIN PE=1 SV=3 6.14 1249.1 - 269507 - - - 0.9003 - 1.688 0.295 - 268.6 1 1 0 0.0011 11 0 0 0 - - - - - 2.6358 1 221125_WJC_METTL3_EV_vs_WT_F10.02988.02988.2 3.24E-07 20-Aug R.ETNGNEDEEGR.Q "sp|Q9BUQ8|DDX23_HUMAN,tr|H0YIL9|H0YIL9_HUMAN" 2 1248.4855 -1 136949 2988 2 1248.485812 625.25 Probable ATP-dependent RNA helicase DDX23 OS=Homo sapiens OX=9606 GN=DDX23 PE=1 SV=3 3.91 1249.3 - 255175 - - - 0.2883 - 1.918 0.671 - 250.2 1 2 0 0.0004 11 0 0 0 0.00E+00 0.00E+00 - - - 5.7588 1 221125_WJC_METTL3_EV_vs_WT_F10.02990.02990.2 5.09E-05 15/24 K.QSHGAAPC[160.03]SGGSQ.- "sp|Q86SG5|S1A7A_HUMAN,sp|P31151|S10A7_HUMAN" 2 1242.5047 - 136951 2990 2 1242.502667 622.2597 Protein S100-A7A OS=Homo sapiens OX=9606 GN=S100A7A PE=1 SV=3 6.73 1249.5 - 138881 - - - -1.6748 - 2.876 0.644 - 563.4 1 2 0 -0.0021 13 0 0 0 - - - - - 6.5082 0.9997 221125_WJC_METTL3_EV_vs_WT_F10.03008.03008.2 0.000132 18-Oct R.TGPSEEKPSR.L "sp|P78332|RBM6_HUMAN,tr|F8WCA5|F8WCA5_HUMAN,tr|E9PGM9|E9PGM9_HUMAN" 3 1086.5306 1.93 136968 3008 2 1086.529459 544.2726 RNA-binding protein 6 OS=Homo sapiens OX=9606 GN=RBM6 PE=1 SV=5 5.81 1251.6 - 220671 - - - -1.006 - 1.771 0.422 - 383 1 2 0 -0.0011 10 0 0 0 1.16E+06 6.03E+05 - - - 3.7529 0.9993 221125_WJC_METTL3_EV_vs_WT_F10.03015.03015.2 0.00222 16-Nov K.QTHSQELC[160.03]K.L "sp|P52732|KIF11_HUMAN,tr|A0A7I2V3A9|A0A7I2V3A9_HUMAN" 2 1129.5186 4.16 136972 3015 2 1129.517712 565.7666 Kinesin-like protein KIF11 OS=Homo sapiens OX=9606 GN=KIF11 PE=1 SV=2 6.74 1252.5 - 3.87E+06 - - - -0.7924 - 1.691 0.31 - 485.3 1 2 0 -0.0009 9 0 0 0 5.69E+07 1.37E+07 - - - 2.8502 0.9976 221125_WJC_METTL3_EV_vs_WT_F10.03016.03016.3 0.692 Nov-36 K.VVVK[136.11]PEK[136.11]TEK[136.11].K "sp|Q9Y520|PRC2C_HUMAN,tr|E7EPN9|E7EPN9_HUMAN" 2 1179.7289 0.94 136973 3016 3 1179.727482 394.2503 Protein PRRC2C OS=Homo sapiens OX=9606 GN=PRRC2C PE=1 SV=4 8.47 1252.5 - 2.54E+06 - - - -1.2223 - 2.128 0.279 - 121.7 1 2 1 -0.0014 10 0 0 0 9.78E+06 1.05E+07 - - - 3.8556 0.9995 221125_WJC_METTL3_EV_vs_WT_F10.03017.03017.3 0.00145 Oct-36 K.VVVKPEKTEK.K "sp|Q9Y520|PRC2C_HUMAN,tr|E7EPN9|E7EPN9_HUMAN" 2 1155.6863 0.94 136974 3017 3 1155.684651 386.2361 Protein PRRC2C OS=Homo sapiens OX=9606 GN=PRRC2C PE=1 SV=4 8.47 1252.6 - 2.15E+06 - - - -1.4476 - 2.048 0.416 - 96.4 1 2 1 -0.0017 10 0 0 0 9.78E+06 1.05E+07 - - - 5.2711 0.9999 221125_WJC_METTL3_EV_vs_WT_F10.03020.03020.2 8.67E-05 16-Dec K.QTHSQELC[160.03]K[136.11].L "sp|P52732|KIF11_HUMAN,tr|A0A7I2V3A9|A0A7I2V3A9_HUMAN" 2 1137.5328 4.16 136977 3020 2 1137.531996 569.7737 Kinesin-like protein KIF11 OS=Homo sapiens OX=9606 GN=KIF11 PE=1 SV=2 6.74 1252.8 - 1.21E+06 - - - -0.7129 - 1.984 0.495 - 656.7 1 2 0 -0.0008 9 0 0 0 5.69E+07 1.37E+07 - - - 4.6789 0.9995 221125_WJC_METTL3_EV_vs_WT_F10.03026.03026.3 2.89E-06 Dec-52 K.NDK[136.11]SEEEQSSSSVK[136.11].K "sp|P07910|HNRPC_HUMAN,tr|B4DY08|B4DY08_HUMAN,tr|G3V5V7|G3V5V7_HUMAN,tr|B2R5W2|B2R5W2_HUMAN,tr|G3V4C1|G3V4C1_HUMAN,tr|G3V2D6|G3V2D6_HUMAN,tr|G3V4W0|G3V4W0_HUMAN,tr|G3V2Q1|G3V2Q1_HUMAN" 8 1568.7137 1.28 136983 3026 3 1568.713592 523.9118 Heterogeneous nuclear ribonucleoproteins C1\C2 OS=Homo sapiens OX=9606 GN=HNRNPC PE=1 SV=4 4.41 1253.5 - 523989 - - - -0.0523 - 2.088 0.407 - 217.1 1 2 1 -0.0001 14 0 0 0 2.46E+06 1.93E+06 - - - 5.0341 0.9999 221125_WJC_METTL3_EV_vs_WT_F10.03028.03028.3 8.60E-07 14/52 K.NDKSEEEQSSSSVK.K "sp|P07910|HNRPC_HUMAN,tr|B4DY08|B4DY08_HUMAN,tr|G3V5V7|G3V5V7_HUMAN,tr|B2R5W2|B2R5W2_HUMAN,tr|G3V4C1|G3V4C1_HUMAN,tr|G3V2D6|G3V2D6_HUMAN,tr|G3V4W0|G3V4W0_HUMAN,tr|G3V2Q1|G3V2Q1_HUMAN" 8 1552.6853 1.28 136985 3028 3 1552.683804 518.569 Heterogeneous nuclear ribonucleoproteins C1\C2 OS=Homo sapiens OX=9606 GN=HNRNPC PE=1 SV=4 4.41 1253.8 - 475184 - - - -0.9467 - 2.532 0.539 - 288.4 1 2 1 -0.0015 14 0 0 0 2.46E+06 1.93E+06 - - - 7.0178 0.9849 221125_WJC_METTL3_EV_vs_WT_F10.03032.03032.2 0.0415 14-Nov Q.THSQELC[160.03]K.L "sp|P52732|KIF11_HUMAN,tr|A0A7I2V3A9|A0A7I2V3A9_HUMAN" 2 1001.46 5.12 136988 3032 2 1001.458813 501.7373 Kinesin-like protein KIF11 OS=Homo sapiens OX=9606 GN=KIF11 PE=1 SV=2 6.41 1254.3 - 317457 - - - -1.2152 - 1.981 0.41 - 605.6 1 1 0 -0.0012 8 0 0 0 4.07E+06 7.94E+05 - - - 4.1306 0.9979 221125_WJC_METTL3_EV_vs_WT_F10.03039.03039.3 0.000597 Nov-40 K.TKQGVTEAAEK.T "sp|O76070|SYUG_HUMAN,sp|Q16143|SYUB_HUMAN,tr|F8W754|F8W754_HUMAN,tr|G4Y816|G4Y816_HUMAN" 4 1160.6037 6.01 136993 3039 3 1160.601396 387.8752 Gamma-synuclein OS=Homo sapiens OX=9606 GN=SNCG PE=1 SV=2 5.81 1255 - 2.64E+06 - - - -1.9998 - 1.995 0.346 - 229.8 1 2 1 -0.0023 11 0 0 0 1.49E+08 2.47E+07 - - - 4.3589 0.9979 221125_WJC_METTL3_EV_vs_WT_F10.03040.03040.3 0.0077 Dec-36 K.EEMDDQDKDK.A "sp|Q9Y2W1|TR150_HUMAN,tr|A0A3B3ITZ9|A0A3B3ITZ9_HUMAN" 2 1251.4925 2.9 136994 3040 3 1251.489384 418.1714 Thyroid hormone receptor-associated protein 3 OS=Homo sapiens OX=9606 GN=THRAP3 PE=1 SV=2 3.96 1255.1 - 1.48E+06 - - - -2.4994 - 2.275 0.333 - 228.7 1 2 1 -0.0031 10 0 0 0 5.49E+07 1.89E+07 - - - 4.6523 0.9989 221125_WJC_METTL3_EV_vs_WT_F10.03042.03042.2 0.00654 14-Sep R.KLTPQGQR.D "sp|P39019|RS19_HUMAN,tr|A0A075B6E2|A0A075B6E2_HUMAN" 2 926.5298 1.14 136996 3042 2 926.527913 464.2722 40S ribosomal protein S19 OS=Homo sapiens OX=9606 GN=RPS19 PE=1 SV=2 11 1255.3 - 823589 - - - -1.9978 - 2.185 0.219 - 367.8 1 2 0 -0.0019 8 0 0 0 2.99E+06 2.62E+06 - - - 3.0153 0.9999 221125_WJC_METTL3_EV_vs_WT_F10.03043.03043.3 1.30E-05 15/36 K.EEMDDQDK[136.11]DK[136.11].A "sp|Q9Y2W1|TR150_HUMAN,tr|A0A3B3ITZ9|A0A3B3ITZ9_HUMAN" 2 1267.5209 2.9 136997 3043 3 1267.518854 423.5142 Thyroid hormone receptor-associated protein 3 OS=Homo sapiens OX=9606 GN=THRAP3 PE=1 SV=2 3.96 1255.4 - 558071 - - - -1.6236 - 2.42 0.587 - 345.6 1 2 1 -0.0021 10 0 0 0 5.49E+07 1.89E+07 - - - 7.6649 0.9926 221125_WJC_METTL3_EV_vs_WT_F10.03047.03047.2 0.00642 28-Dec D.SSSGGGDSAAAGASR.L sp|P23378|GCSP_HUMAN 1 1236.5331 0.3 137001 3047 2 1236.53215 619.2738 "Glycine dehydrogenase (decarboxylating), mitochondrial OS=Homo sapiens OX=9606 GN=GLDC PE=1 SV=2" 5.55 1256 - 217695 - - - -0.7448 - 2.402 0.511 - 324.1 1 1 0 -0.0009 15 0 0 0 1.49E+06 4.99E+06 - - - 4.9694 0.9787 221125_WJC_METTL3_EV_vs_WT_F10.03048.03048.2 0.000285 18-Aug K.EEMDDQDK[136.11]DK[136.11].A "sp|Q9Y2W1|TR150_HUMAN,tr|A0A3B3ITZ9|A0A3B3ITZ9_HUMAN" 2 1267.5209 2.44 137002 3048 2 1267.514949 634.7677 Thyroid hormone receptor-associated protein 3 OS=Homo sapiens OX=9606 GN=THRAP3 PE=1 SV=2 3.96 1256.1 - 174950 - - - -4.7045 - 1.945 0.529 - 259.4 1 2 1 -0.006 10 0 0 0 8.72E+06 3.57E+06 - - - 4.8033 0.9966 221125_WJC_METTL3_EV_vs_WT_F10.03056.03056.2 0.000372 20-Nov K.TKQGVTEAAEK.T "sp|O76070|SYUG_HUMAN,sp|Q16143|SYUB_HUMAN,tr|F8W754|F8W754_HUMAN,tr|G4Y816|G4Y816_HUMAN" 4 1160.6037 1.8 137008 3056 2 1160.601457 581.3091 Gamma-synuclein OS=Homo sapiens OX=9606 GN=SNCG PE=1 SV=2 5.81 1257.1 - 2.59E+06 - - - -1.9473 - 2.108 0.474 - 300.1 1 2 1 -0.0023 11 0 0 0 1.18E+07 6.54E+06 - - - 4.5587 0.9999 221125_WJC_METTL3_EV_vs_WT_F10.03057.03057.3 0.000473 13/40 R.VQDAVQQHQQK.M "sp|Q9NVI7|ATD3A_HUMAN,tr|Q5SV16|Q5SV16_HUMAN" 2 1307.6582 1.85 137009 3057 3 1307.656164 436.8933 ATPase family AAA domain-containing protein 3A OS=Homo sapiens OX=9606 GN=ATAD3A PE=1 SV=2 6.71 1257.1 - 2.76E+06 - - - -1.5662 - 2.564 0.387 - 311.2 1 2 0 -0.002 11 0 0 0 5.09E+07 2.75E+07 - - - 5.5289 0.9999 221125_WJC_METTL3_EV_vs_WT_F10.03058.03058.3 0.000303 15/40 R.VQDAVQQHQQK[136.11].M "sp|Q9NVI7|ATD3A_HUMAN,tr|Q5SV16|Q5SV16_HUMAN" 2 1315.6724 1.85 137010 3058 3 1315.669952 439.5647 ATPase family AAA domain-containing protein 3A OS=Homo sapiens OX=9606 GN=ATAD3A PE=1 SV=2 6.71 1257.2 - 2.58E+06 - - - -1.8698 - 2.548 0.385 - 356.9 1 2 0 -0.0025 11 0 0 0 5.09E+07 2.75E+07 - - - 5.4887 1 221125_WJC_METTL3_EV_vs_WT_F10.03059.03059.2 1.38E-15 17/26 R.PSQAAGDNQGDEAK.E "sp|Q9Y2W1|TR150_HUMAN,tr|A0A3B3ITZ9|A0A3B3ITZ9_HUMAN" 2 1386.6012 2.74 137011 3059 2 1386.599236 694.3079 Thyroid hormone receptor-associated protein 3 OS=Homo sapiens OX=9606 GN=THRAP3 PE=1 SV=2 4.03 1257.3 - 2.24E+06 - - - -1.3811 - 3.606 0.774 - 1320.8 1 1 0 -0.0019 14 0 0 0 2.90E+07 1.06E+07 - - - 7.9758 0.9966 221125_WJC_METTL3_EV_vs_WT_F10.03060.03060.2 0.000777 14-Oct R.QREESYSR.M "sp|P23246|SFPQ_HUMAN,tr|H0Y9K7|H0Y9K7_HUMAN,tr|H0Y9U2|H0Y9U2_HUMAN" 3 1053.4839 0.82 137012 3060 2 1053.482378 527.7492 "Splicing factor, proline- and glutamine-rich OS=Homo sapiens OX=9606 GN=SFPQ PE=1 SV=2" 6.14 1257.4 - 1.76E+06 - - - -1.4789 - 2.124 0.379 - 217.1 1 2 1 -0.0016 8 0 0 0 1.02E+07 1.24E+07 - - - 4.1117 0.9973 221125_WJC_METTL3_EV_vs_WT_F10.03062.03062.2 0.000323 20-Nov K.TK[136.11]QGVTEAAEK[136.11].T "sp|O76070|SYUG_HUMAN,sp|Q16143|SYUB_HUMAN,tr|F8W754|F8W754_HUMAN,tr|G4Y816|G4Y816_HUMAN" 4 1176.6321 1.78 137014 3062 2 1176.630222 589.3233 Gamma-synuclein OS=Homo sapiens OX=9606 GN=SNCG PE=1 SV=2 5.81 1257.5 - 1.72E+06 - - - -1.6105 - 2.129 0.472 - 282.2 1 2 1 -0.0019 11 0 0 0 1.16E+07 6.54E+06 - - - 4.5708 0.9944 221125_WJC_METTL3_EV_vs_WT_F10.03064.03064.3 0.0219 Sep-40 K.DK[136.11]NSAVTSSAR[166.11].G sp|Q9Y6D9|MD1L1_HUMAN 1 1152.5854 0.15 137016 3064 3 1152.583557 385.2024 Mitotic spindle assembly checkpoint protein MAD1 OS=Homo sapiens OX=9606 GN=MAD1L1 PE=1 SV=2 8.75 1257.6 - 1.26E+06 - - - -1.586 - 1.753 0.292 - 186 1 2 1 -0.0018 11 0 0 0 7.04E+05 4.74E+06 - - - 3.3896 1 221125_WJC_METTL3_EV_vs_WT_F10.03066.03066.2 6.60E-08 14/28 D.SSSGGGDSAAAGASR[166.11].L sp|P23378|GCSP_HUMAN 1 1246.5413 0.35 137018 3066 2 1246.539697 624.2779 "Glycine dehydrogenase (decarboxylating), mitochondrial OS=Homo sapiens OX=9606 GN=GLDC PE=1 SV=2" 5.55 1257.8 - 759349 - - - -1.3188 - 2.62 0.614 - 659 1 1 0 -0.0016 15 0 0 0 1.49E+06 4.28E+06 - - - 5.9435 1 221125_WJC_METTL3_EV_vs_WT_F10.03067.03067.2 2.55E-07 18/26 R.PSQAAGDNQGDEAK[136.11].E "sp|Q9Y2W1|TR150_HUMAN,tr|A0A3B3ITZ9|A0A3B3ITZ9_HUMAN" 2 1394.6154 3.06 137019 3067 2 1394.612997 698.315 Thyroid hormone receptor-associated protein 3 OS=Homo sapiens OX=9606 GN=THRAP3 PE=1 SV=2 4.03 1258 - 754910 - - - -1.6879 - 3.702 0.703 - 1393.9 1 1 0 -0.0024 14 0 0 0 2.90E+07 9.47E+06 - - - 7.5172 0.9965 221125_WJC_METTL3_EV_vs_WT_F10.03068.03068.2 0.000515 20-Sep K.DK[136.11]NSAVTSSAR[166.11].G sp|Q9Y6D9|MD1L1_HUMAN 1 1152.5854 -1 137020 3068 2 1152.584061 577.3 Mitotic spindle assembly checkpoint protein MAD1 OS=Homo sapiens OX=9606 GN=MAD1L1 PE=1 SV=2 8.75 1258.1 - 633992 - - - -1.1487 - 1.893 0.414 - 290.5 1 2 1 -0.0013 11 0 0 0 0.00E+00 0.00E+00 - - - 3.8248 0.9975 221125_WJC_METTL3_EV_vs_WT_F10.03077.03077.2 0.075 16-Aug K.HSQELTNEK.E sp|Q6UVJ0|SAS6_HUMAN 1 1084.5149 0.49 137028 3077 2 1084.516098 543.2647 Spindle assembly abnormal protein 6 homolog OS=Homo sapiens OX=9606 GN=SASS6 PE=1 SV=1 5.4 1259.2 - 276419 - - - 1.1028 - 1.267 0.289 - 134.4 1 2 0 0.0012 9 0 0 0 9.34E+05 1.90E+06 - - - 1.8598 0.9888 221125_WJC_METTL3_EV_vs_WT_F10.03078.03078.3 0.0415 Sep-32 K.QTHSQELC[160.03]K[136.11].L "sp|P52732|KIF11_HUMAN,tr|A0A7I2V3A9|A0A7I2V3A9_HUMAN" 2 1137.5328 0.001 137029 3078 3 1137.530502 380.1849 Kinesin-like protein KIF11 OS=Homo sapiens OX=9606 GN=KIF11 PE=1 SV=2 6.74 1259.3 - 1.11E+06 - - - -2.0263 - 1.68 0.18 - 92.1 1 2 0 -0.0023 9 0 0 0 0.00E+00 4.11E+07 - - - 2.1097 1 221125_WJC_METTL3_EV_vs_WT_F10.03082.03082.2 1.1 14/20 R.SASASHQADIK.E "sp|Q14739|LBR_HUMAN,tr|A0A494C1L1|A0A494C1L1_HUMAN,tr|C9JXK0|C9JXK0_HUMAN" 3 1113.5415 1.66 137033 3082 2 1113.535566 557.778 Delta(14)-sterol reductase LBR OS=Homo sapiens OX=9606 GN=LBR PE=1 SV=2 6.46 1259.7 - 757135 - - - -5.2849 - 2.756 0.557 - 688.7 1 2 0 -0.0059 11 0 0 0 3.99E+06 2.40E+06 - - - 5.8957 0.9997 221125_WJC_METTL3_EV_vs_WT_F10.03083.03083.2 0.0168 13/20 R.VQDAVQQHQQK.M "sp|Q9NVI7|ATD3A_HUMAN,tr|Q5SV16|Q5SV16_HUMAN" 2 1307.6582 1.26 137034 3083 2 1307.655295 654.8364 ATPase family AAA domain-containing protein 3A OS=Homo sapiens OX=9606 GN=ATAD3A PE=1 SV=2 6.71 1259.8 - 756725 - - - -2.2307 - 2.613 0.483 - 876.1 1 2 0 -0.0029 11 0 0 0 3.69E+06 2.93E+06 - - - 5.2059 1 221125_WJC_METTL3_EV_vs_WT_F10.03084.03084.2 1.58E-08 16/20 R.SASASHQADIK[136.11].E "sp|Q14739|LBR_HUMAN,tr|A0A494C1L1|A0A494C1L1_HUMAN,tr|C9JXK0|C9JXK0_HUMAN" 3 1121.5557 1.66 137035 3084 2 1121.554107 561.7851 Delta(14)-sterol reductase LBR OS=Homo sapiens OX=9606 GN=LBR PE=1 SV=2 6.46 1259.9 - 639479 - - - -1.3767 - 2.81 0.529 - 1085.5 1 2 0 -0.0015 11 0 0 0 3.99E+06 2.40E+06 - - - 5.7427 0.9997 221125_WJC_METTL3_EV_vs_WT_F10.03085.03085.2 0.00116 20-Dec R.VQDAVQQHQQK[136.11].M "sp|Q9NVI7|ATD3A_HUMAN,tr|Q5SV16|Q5SV16_HUMAN" 2 1315.6724 1.26 137036 3085 2 1315.67003 658.8435 ATPase family AAA domain-containing protein 3A OS=Homo sapiens OX=9606 GN=ATAD3A PE=1 SV=2 6.71 1260.1 - 590522 - - - -1.8105 - 2.184 0.434 - 378.1 1 2 0 -0.0024 11 0 0 0 3.69E+06 2.93E+06 - - - 4.359 0.992 221125_WJC_METTL3_EV_vs_WT_F10.03086.03086.2 0.0047 20-Aug K.DKNSAVTSSAR.G sp|Q9Y6D9|MD1L1_HUMAN 1 1134.5629 -1 137037 3086 2 1134.560988 568.2887 Mitotic spindle assembly checkpoint protein MAD1 OS=Homo sapiens OX=9606 GN=MAD1L1 PE=1 SV=2 8.75 1260.2 - 486495 - - - -1.6985 - 1.777 0.357 - 236.3 1 2 1 -0.0019 11 0 0 0 0.00E+00 0.00E+00 - - - 3.2325 0.9998 221125_WJC_METTL3_EV_vs_WT_F10.03088.03088.2 8.98E-05 15/18 K.K[136.11]ETQSPEQVK[136.11].S "sp|Q9NYF8|BCLF1_HUMAN,tr|E9PKI6|E9PKI6_HUMAN,tr|A0A1W2PQ43|A0A1W2PQ43_HUMAN,tr|E9PK91|E9PK91_HUMAN,tr|E9PK09|E9PK09_HUMAN,tr|E9PQN2|E9PQN2_HUMAN" 6 1188.6321 2.73 137039 3088 2 1188.629269 595.3233 Bcl-2-associated transcription factor 1 OS=Homo sapiens OX=9606 GN=BCLAF1 PE=1 SV=2 6.14 1260.5 - 325366 - - - -2.396 - 2.715 0.525 - 818.5 1 2 0 -0.0028 10 0 0 0 2.82E+08 1.03E+08 - - - 5.7057 0.9602 221125_WJC_METTL3_EV_vs_WT_F10.03089.03089.2 0.0024 18-Sep V.QDAVQQHQQK[136.11].M "sp|Q9NVI7|ATD3A_HUMAN,tr|Q5SV16|Q5SV16_HUMAN" 2 1216.604 -1 137040 3089 2 1216.602838 609.3093 ATPase family AAA domain-containing protein 3A OS=Homo sapiens OX=9606 GN=ATAD3A PE=1 SV=2 6.74 1260.6 - 269080 - - - -0.9535 - 1.553 0.351 - 221.3 1 1 0 -0.0012 10 0 0 0 0.00E+00 0.00E+00 - - - 2.8618 0.9687 221125_WJC_METTL3_EV_vs_WT_F10.03090.03090.2 0.000432 18-Dec V.QDAVQQHQQK.M "sp|Q9NVI7|ATD3A_HUMAN,tr|Q5SV16|Q5SV16_HUMAN" 2 1208.5898 1.38 137041 3090 2 1208.586558 605.3022 ATPase family AAA domain-containing protein 3A OS=Homo sapiens OX=9606 GN=ATAD3A PE=1 SV=2 6.74 1260.7 - 204451 - - - -2.6808 - 2.173 0.443 - 435.6 1 1 0 -0.0032 10 0 0 0 9.37E+05 6.79E+05 - - - 4.4783 0.9995 221125_WJC_METTL3_EV_vs_WT_F10.03094.03094.3 0.00332 Nov-36 K.KETQSPEQVK.S "sp|Q9NYF8|BCLF1_HUMAN,tr|E9PKI6|E9PKI6_HUMAN,tr|A0A1W2PQ43|A0A1W2PQ43_HUMAN,tr|E9PK91|E9PK91_HUMAN,tr|E9PK09|E9PK09_HUMAN,tr|E9PQN2|E9PQN2_HUMAN" 6 1172.6037 2.42 137043 3094 3 1172.600282 391.8752 Bcl-2-associated transcription factor 1 OS=Homo sapiens OX=9606 GN=BCLAF1 PE=1 SV=2 6.14 1261.3 - 6.59E+06 - - - -2.9294 - 2.293 0.356 - 250.2 1 2 0 -0.0034 10 0 0 0 6.08E+08 2.52E+08 - - - 4.9317 0.9998 221125_WJC_METTL3_EV_vs_WT_F10.03096.03096.2 7.86E-05 14/18 K.KETQSPEQVK.S "sp|Q9NYF8|BCLF1_HUMAN,tr|E9PKI6|E9PKI6_HUMAN,tr|A0A1W2PQ43|A0A1W2PQ43_HUMAN,tr|E9PK91|E9PK91_HUMAN,tr|E9PK09|E9PK09_HUMAN,tr|E9PQN2|E9PQN2_HUMAN" 6 1172.6037 2.73 137045 3096 2 1172.601428 587.3091 Bcl-2-associated transcription factor 1 OS=Homo sapiens OX=9606 GN=BCLAF1 PE=1 SV=2 6.14 1261.4 - 2.59E+06 - - - -1.9521 - 2.792 0.486 - 731.7 1 2 0 -0.0023 10 0 0 0 2.82E+08 1.03E+08 - - - 5.4959 0.9994 221125_WJC_METTL3_EV_vs_WT_F10.03097.03097.3 0.0349 Nov-40 K.EAEGSSAEYKK.E "sp|P49321|NASP_HUMAN,tr|H0YDS9|H0YDS9_HUMAN,tr|Q5T624|Q5T624_HUMAN,tr|H0YF33|H0YF33_HUMAN,tr|E9PRH9|E9PRH9_HUMAN" 5 1197.5513 0.48 137046 3097 3 1197.547997 400.1911 Nuclear autoantigenic sperm protein OS=Homo sapiens OX=9606 GN=NASP PE=1 SV=2 4.79 1261.5 - 2.32E+06 - - - -2.7974 - 2.229 0.348 - 166 1 2 0 -0.0034 11 0 0 0 9.76E+06 2.02E+07 - - - 4.696 1 221125_WJC_METTL3_EV_vs_WT_F10.03101.03101.2 5.20E-12 14/16 K.HYEC[160.03]ENC[160.03]AK.V "sp|Q03112|MECOM_HUMAN,tr|H9KVD4|H9KVD4_HUMAN,tr|E7EUL6|E7EUL6_HUMAN,tr|A0A0C3SFZ7|A0A0C3SFZ7_HUMAN" 4 1209.4543 1.61 137050 3101 2 1209.452464 605.7344 Histone-lysine N-methyltransferase MECOM OS=Homo sapiens OX=9606 GN=MECOM PE=1 SV=3 5.4 1261.9 - 576077 - - - -1.5123 - 2.58 0.71 - 612.5 1 2 0 -0.0018 9 0 0 0 6.55E+06 4.07E+06 - - - 7.0265 0.9991 221125_WJC_METTL3_EV_vs_WT_F10.03106.03106.2 0.0681 14-Jul K.K[136.11]DENEIEK[136.11].L "sp|Q14683|SMC1A_HUMAN,tr|G8JLG1|G8JLG1_HUMAN,tr|A0A6Q8PHC3|A0A6Q8PHC3_HUMAN" 3 1019.5106 1.68 137055 3106 2 1019.510034 510.7626 Structural maintenance of chromosomes protein 1A OS=Homo sapiens OX=9606 GN=SMC1A PE=1 SV=2 4.41 1262.5 - 204116 - - - -0.5601 - 1.59 0.284 - 152.5 1 2 0 -0.0006 8 0 0 0 6.64E+06 3.95E+06 - - - 2.537 0.9999 221125_WJC_METTL3_EV_vs_WT_F10.03110.03110.3 0.0804 15/32 K.KFVEEQHTK.K sp|Q96A49|SYAP1_HUMAN 1 1144.5877 1.32 137057 3110 3 1144.584955 382.5365 Synapse-associated protein 1 OS=Homo sapiens OX=9606 GN=SYAP1 PE=1 SV=1 6.76 1263 - 1.26E+07 - - - -2.3747 - 2.748 0.422 - 247.6 1 2 0 -0.0027 9 0 0 0 1.55E+08 1.18E+08 - - - 6.2907 0.9729 221125_WJC_METTL3_EV_vs_WT_F10.03111.03111.2 0.23 12-Jul K.DEDYK[136.11]QR[166.11].T "sp|Q00839|HNRPU_HUMAN,tr|A0A1W2PQL0|A0A1W2PQL0_HUMAN,tr|A0A1W2PPL4|A0A1W2PPL4_HUMAN,tr|A0A1W2PQ74|A0A1W2PQ74_HUMAN,tr|Q5RI18|Q5RI18_HUMAN,tr|A0A1W2PP35|A0A1W2PP35_HUMAN,tr|A0A1W2PPS1|A0A1W2PPS1_HUMAN,tr|A0A1W2PRZ7|A0A1W2PRZ7_HUMAN,tr|A0A1W2PPH7|A0A1W2PPH7_HUMAN,tr|A0A1W2PQD4|A0A1W2PQD4_HUMAN,tr|A0A1W2PP34|A0A1W2PP34_HUMAN,tr|A0A1X7SBS1|A0A1X7SBS1_HUMAN" 12 970.4475 0.94 137058 3111 2 970.445038 486.231 Heterogeneous nuclear ribonucleoprotein U OS=Homo sapiens OX=9606 GN=HNRNPU PE=1 SV=6 4.56 1263 - 3.88E+06 - - - -2.5308 - 1.578 0.285 - 398.5 1 2 1 -0.0025 7 0 0 0 8.72E+07 9.28E+07 - - - 2.5906 0.9876 221125_WJC_METTL3_EV_vs_WT_F10.03114.03114.2 4.57E-05 12-Aug K.DEDYKQR.T "sp|Q00839|HNRPU_HUMAN,tr|A0A1W2PQL0|A0A1W2PQL0_HUMAN,tr|A0A1W2PPL4|A0A1W2PPL4_HUMAN,tr|A0A1W2PQ74|A0A1W2PQ74_HUMAN,tr|Q5RI18|Q5RI18_HUMAN,tr|A0A1W2PP35|A0A1W2PP35_HUMAN,tr|A0A1W2PPS1|A0A1W2PPS1_HUMAN,tr|A0A1W2PRZ7|A0A1W2PRZ7_HUMAN,tr|A0A1W2PPH7|A0A1W2PPH7_HUMAN,tr|A0A1W2PQD4|A0A1W2PQD4_HUMAN,tr|A0A1W2PP34|A0A1W2PP34_HUMAN,tr|A0A1X7SBS1|A0A1X7SBS1_HUMAN" 12 952.425 0.94 137061 3114 2 952.422733 477.2198 Heterogeneous nuclear ribonucleoprotein U OS=Homo sapiens OX=9606 GN=HNRNPU PE=1 SV=6 4.56 1263.2 - 2.92E+06 - - - -2.4054 - 1.793 0.325 - 452.5 1 2 1 -0.0023 7 0 0 0 8.72E+07 9.28E+07 - - - 3.2908 1 221125_WJC_METTL3_EV_vs_WT_F10.03119.03119.2 5.02E-08 16-Dec K.HYEC[160.03]ENC[160.03]AK[136.11].V "sp|Q03112|MECOM_HUMAN,tr|H9KVD4|H9KVD4_HUMAN,tr|E7EUL6|E7EUL6_HUMAN,tr|A0A0C3SFZ7|A0A0C3SFZ7_HUMAN" 4 1217.4685 1.61 137066 3119 2 1217.464958 609.7415 Histone-lysine N-methyltransferase MECOM OS=Homo sapiens OX=9606 GN=MECOM PE=1 SV=3 5.4 1263.6 - 533738 - - - -2.9036 - 1.945 0.649 - 387.7 1 2 0 -0.0035 9 0 0 0 6.55E+06 4.07E+06 - - - 5.758 0.9992 221125_WJC_METTL3_EV_vs_WT_F10.03136.03136.2 0.00239 16-Jul K.KFVEEQHTK.K sp|Q96A49|SYAP1_HUMAN 1 1144.5877 1.26 137080 3136 2 1144.585184 573.3011 Synapse-associated protein 1 OS=Homo sapiens OX=9606 GN=SYAP1 PE=1 SV=1 6.76 1265.5 - 1.07E+06 - - - -2.1746 - 1.742 0.381 - 135.9 1 2 0 -0.0025 9 0 0 0 1.03E+07 8.22E+06 - - - 3.46 1 221125_WJC_METTL3_EV_vs_WT_F10.03138.03138.3 1.04E-05 Dec-32 K.EDTEEHHLR.D "sp|Q32P51|RA1L2_HUMAN,sp|P09651|ROA1_HUMAN,sp|P22626|ROA2_HUMAN,tr|A0A7I2YQN4|A0A7I2YQN4_HUMAN,tr|A0A7I2YQX9|A0A7I2YQX9_HUMAN,tr|A0A7I2V4N0|A0A7I2V4N0_HUMAN,tr|A0A024RA28|A0A024RA28_HUMAN,tr|A0A7I2V4N1|A0A7I2V4N1_HUMAN,tr|A0A7I2V4I6|A0A7I2V4I6_HUMAN,tr|F8VZ49|F8VZ49_HUMAN,tr|A0A7I2V3R8|A0A7I2V3R8_HUMAN,tr|A0A087WUI2|A0A087WUI2_HUMAN,tr|A0A7I2V4S4|A0A7I2V4S4_HUMAN,tr|F8VTQ5|F8VTQ5_HUMAN,tr|F8W6I7|F8W6I7_HUMAN,tr|A0A7I2V2L6|A0A7I2V2L6_HUMAN,tr|A0A7I2V323|A0A7I2V323_HUMAN,tr|A0A7I2V3W0|A0A7I2V3W0_HUMAN,tr|A0A7I2V5U9|A0A7I2V5U9_HUMAN,tr|A0A2R8Y4L2|A0A2R8Y4L2_HUMAN,tr|A0A7I2V3P1|A0A7I2V3P1_HUMAN,tr|A0A7I2V3P7|A0A7I2V3P7_HUMAN" 22 1164.516 1.38 137081 3138 3 1164.513027 389.1793 Heterogeneous nuclear ribonucleoprotein A1-like 2 OS=Homo sapiens OX=9606 GN=HNRNPA1L2 PE=2 SV=2 4.8 1265.7 - 3.81E+07 - - - -2.5221 - 2.361 0.547 - 432.3 1 2 0 -0.0029 9 0 0 0 1.64E+09 1.18E+09 - - - 7.2268 0.9722 221125_WJC_METTL3_EV_vs_WT_F10.03140.03140.2 0.000697 12-Oct D.TEEHHLR[166.11].D "sp|Q32P51|RA1L2_HUMAN,sp|P09651|ROA1_HUMAN,sp|P22626|ROA2_HUMAN,tr|A0A7I2YQN4|A0A7I2YQN4_HUMAN,tr|A0A7I2YQX9|A0A7I2YQX9_HUMAN,tr|A0A7I2V4N0|A0A7I2V4N0_HUMAN,tr|A0A024RA28|A0A024RA28_HUMAN,tr|A0A7I2V4N1|A0A7I2V4N1_HUMAN,tr|A0A7I2V4I6|A0A7I2V4I6_HUMAN,tr|F8VZ49|F8VZ49_HUMAN,tr|A0A7I2V3R8|A0A7I2V3R8_HUMAN,tr|A0A087WUI2|A0A087WUI2_HUMAN,tr|A0A7I2V4S4|A0A7I2V4S4_HUMAN,tr|F8VTQ5|F8VTQ5_HUMAN,tr|F8W6I7|F8W6I7_HUMAN,tr|A0A7I2V2L6|A0A7I2V2L6_HUMAN,tr|A0A7I2V323|A0A7I2V323_HUMAN,tr|A0A7I2V3W0|A0A7I2V3W0_HUMAN,tr|A0A7I2V5U9|A0A7I2V5U9_HUMAN,tr|A0A2R8Y4L2|A0A2R8Y4L2_HUMAN,tr|A0A7I2V3P1|A0A7I2V3P1_HUMAN,tr|A0A7I2V3P7|A0A7I2V3P7_HUMAN" 22 930.4547 1.28 137083 3140 2 930.452304 466.2346 Heterogeneous nuclear ribonucleoprotein A1-like 2 OS=Homo sapiens OX=9606 GN=HNRNPA1L2 PE=2 SV=2 5.94 1265.9 - 1.26E+06 - - - -2.5729 - 2.041 0.439 - 646 1 1 0 -0.0024 7 0 0 0 5.92E+07 4.64E+07 - - - 4.5433 0.9806 221125_WJC_METTL3_EV_vs_WT_F10.03141.03141.2 0.000324 12-Oct D.TEEHHLR.D "sp|Q32P51|RA1L2_HUMAN,sp|P09651|ROA1_HUMAN,sp|P22626|ROA2_HUMAN,tr|A0A7I2YQN4|A0A7I2YQN4_HUMAN,tr|A0A7I2YQX9|A0A7I2YQX9_HUMAN,tr|A0A7I2V4N0|A0A7I2V4N0_HUMAN,tr|A0A024RA28|A0A024RA28_HUMAN,tr|A0A7I2V4N1|A0A7I2V4N1_HUMAN,tr|A0A7I2V4I6|A0A7I2V4I6_HUMAN,tr|F8VZ49|F8VZ49_HUMAN,tr|A0A7I2V3R8|A0A7I2V3R8_HUMAN,tr|A0A087WUI2|A0A087WUI2_HUMAN,tr|A0A7I2V4S4|A0A7I2V4S4_HUMAN,tr|F8VTQ5|F8VTQ5_HUMAN,tr|F8W6I7|F8W6I7_HUMAN,tr|A0A7I2V2L6|A0A7I2V2L6_HUMAN,tr|A0A7I2V323|A0A7I2V323_HUMAN,tr|A0A7I2V3W0|A0A7I2V3W0_HUMAN,tr|A0A7I2V5U9|A0A7I2V5U9_HUMAN,tr|A0A2R8Y4L2|A0A2R8Y4L2_HUMAN,tr|A0A7I2V3P1|A0A7I2V3P1_HUMAN,tr|A0A7I2V3P7|A0A7I2V3P7_HUMAN" 22 920.4464 1.28 137084 3141 2 920.444266 461.2305 Heterogeneous nuclear ribonucleoprotein A1-like 2 OS=Homo sapiens OX=9606 GN=HNRNPA1L2 PE=2 SV=2 5.94 1266 - 1.07E+06 - - - -2.3489 - 2.136 0.467 - 739.3 1 1 0 -0.0022 7 0 0 0 5.92E+07 4.64E+07 - - - 4.8943 0.9997 221125_WJC_METTL3_EV_vs_WT_F10.03146.03146.3 0.00303 Nov-32 K.EDTEEHHLR[166.11].D "sp|Q32P51|RA1L2_HUMAN,sp|P09651|ROA1_HUMAN,sp|P22626|ROA2_HUMAN,tr|A0A7I2YQN4|A0A7I2YQN4_HUMAN,tr|A0A7I2YQX9|A0A7I2YQX9_HUMAN,tr|A0A7I2V4N0|A0A7I2V4N0_HUMAN,tr|A0A024RA28|A0A024RA28_HUMAN,tr|A0A7I2V4N1|A0A7I2V4N1_HUMAN,tr|A0A7I2V4I6|A0A7I2V4I6_HUMAN,tr|F8VZ49|F8VZ49_HUMAN,tr|A0A7I2V3R8|A0A7I2V3R8_HUMAN,tr|A0A087WUI2|A0A087WUI2_HUMAN,tr|A0A7I2V4S4|A0A7I2V4S4_HUMAN,tr|F8VTQ5|F8VTQ5_HUMAN,tr|F8W6I7|F8W6I7_HUMAN,tr|A0A7I2V2L6|A0A7I2V2L6_HUMAN,tr|A0A7I2V323|A0A7I2V323_HUMAN,tr|A0A7I2V3W0|A0A7I2V3W0_HUMAN,tr|A0A7I2V5U9|A0A7I2V5U9_HUMAN,tr|A0A2R8Y4L2|A0A2R8Y4L2_HUMAN,tr|A0A7I2V3P1|A0A7I2V3P1_HUMAN,tr|A0A7I2V3P7|A0A7I2V3P7_HUMAN" 22 1174.5242 1.38 137087 3146 3 1174.520508 392.5154 Heterogeneous nuclear ribonucleoprotein A1-like 2 OS=Homo sapiens OX=9606 GN=HNRNPA1L2 PE=2 SV=2 4.8 1266.6 - 6.77E+07 - - - -3.1723 - 2.258 0.401 - 312.7 1 2 0 -0.0037 9 0 0 0 1.64E+09 1.18E+09 - - - 5.4644 0.9993 221125_WJC_METTL3_EV_vs_WT_F10.03147.03147.2 0.39 14-Dec R.SEIDHVKK.Q "sp|P48668|K2C6C_HUMAN,sp|P04259|K2C6B_HUMAN,sp|P02538|K2C6A_HUMAN" 3 954.5134 999 137088 3147 2 954.51078 478.264 "Keratin, type II cytoskeletal 6C OS=Homo sapiens OX=9606 GN=KRT6C PE=1 SV=3" 6.47 1266.7 - 2.14E+07 - - - -2.792 - 2.357 0.348 - 713.9 1 2 0 -0.0027 8 0 0 0 3.22E+08 0.00E+00 - - - 4.1963 0.9524 221125_WJC_METTL3_EV_vs_WT_F10.03152.03152.2 0.000183 14-Nov E.DTEEHHLR.D "sp|Q32P51|RA1L2_HUMAN,sp|P09651|ROA1_HUMAN,sp|P22626|ROA2_HUMAN,tr|A0A7I2YQN4|A0A7I2YQN4_HUMAN,tr|A0A7I2YQX9|A0A7I2YQX9_HUMAN,tr|A0A7I2V4N0|A0A7I2V4N0_HUMAN,tr|A0A024RA28|A0A024RA28_HUMAN,tr|A0A7I2V4N1|A0A7I2V4N1_HUMAN,tr|A0A7I2V4I6|A0A7I2V4I6_HUMAN,tr|F8VZ49|F8VZ49_HUMAN,tr|A0A7I2V3R8|A0A7I2V3R8_HUMAN,tr|A0A087WUI2|A0A087WUI2_HUMAN,tr|A0A7I2V4S4|A0A7I2V4S4_HUMAN,tr|F8VTQ5|F8VTQ5_HUMAN,tr|F8W6I7|F8W6I7_HUMAN,tr|A0A7I2V2L6|A0A7I2V2L6_HUMAN,tr|A0A7I2V323|A0A7I2V323_HUMAN,tr|A0A7I2V3W0|A0A7I2V3W0_HUMAN,tr|A0A7I2V5U9|A0A7I2V5U9_HUMAN,tr|A0A2R8Y4L2|A0A2R8Y4L2_HUMAN,tr|A0A7I2V3P1|A0A7I2V3P1_HUMAN,tr|A0A7I2V3P7|A0A7I2V3P7_HUMAN" 22 1035.4734 1.47 137093 3152 2 1035.470698 518.744 Heterogeneous nuclear ribonucleoprotein A1-like 2 OS=Homo sapiens OX=9606 GN=HNRNPA1L2 PE=2 SV=2 5.27 1266.9 - 2.51E+06 - - - -2.5814 - 2.12 0.335 - 876.7 1 1 0 -0.0027 8 0 0 0 6.23E+07 4.24E+07 - - - 3.7807 0.8368 221125_WJC_METTL3_EV_vs_WT_F10.03153.03153.2 0.727 14-Sep E.DTEEHHLR[166.11].D "sp|Q32P51|RA1L2_HUMAN,sp|P09651|ROA1_HUMAN,sp|P22626|ROA2_HUMAN,tr|A0A7I2YQN4|A0A7I2YQN4_HUMAN,tr|A0A7I2YQX9|A0A7I2YQX9_HUMAN,tr|A0A7I2V4N0|A0A7I2V4N0_HUMAN,tr|A0A024RA28|A0A024RA28_HUMAN,tr|A0A7I2V4N1|A0A7I2V4N1_HUMAN,tr|A0A7I2V4I6|A0A7I2V4I6_HUMAN,tr|F8VZ49|F8VZ49_HUMAN,tr|A0A7I2V3R8|A0A7I2V3R8_HUMAN,tr|A0A087WUI2|A0A087WUI2_HUMAN,tr|A0A7I2V4S4|A0A7I2V4S4_HUMAN,tr|F8VTQ5|F8VTQ5_HUMAN,tr|F8W6I7|F8W6I7_HUMAN,tr|A0A7I2V2L6|A0A7I2V2L6_HUMAN,tr|A0A7I2V323|A0A7I2V323_HUMAN,tr|A0A7I2V3W0|A0A7I2V3W0_HUMAN,tr|A0A7I2V5U9|A0A7I2V5U9_HUMAN,tr|A0A2R8Y4L2|A0A2R8Y4L2_HUMAN,tr|A0A7I2V3P1|A0A7I2V3P1_HUMAN,tr|A0A7I2V3P7|A0A7I2V3P7_HUMAN" 22 1045.4816 1.47 137094 3153 2 1045.477741 523.7481 Heterogeneous nuclear ribonucleoprotein A1-like 2 OS=Homo sapiens OX=9606 GN=HNRNPA1L2 PE=2 SV=2 5.27 1267 - 2.09E+06 - - - -3.7303 - 1.838 0.314 - 284.6 1 1 0 -0.0039 8 0 0 0 6.23E+07 4.24E+07 - - - 3.1947 0.9988 221125_WJC_METTL3_EV_vs_WT_F10.03154.03154.2 9.88E-06 16-Oct K.YTTTSSSSR.K "sp|P48668|K2C6C_HUMAN,sp|P04259|K2C6B_HUMAN,sp|P02538|K2C6A_HUMAN" 3 988.4462 96.57 137095 3154 2 988.449958 495.2304 "Keratin, type II cytoskeletal 6C OS=Homo sapiens OX=9606 GN=KRT6C PE=1 SV=3" 8.75 1267.1 - 1.08E+06 - - - 3.8485 - 1.708 0.546 - 338.9 1 2 0 0.0038 9 0 0 0 5.54E+06 5.74E+04 - - - 4.6213 0.9904 221125_WJC_METTL3_EV_vs_WT_F10.03155.03155.2 1.44E-06 22-Nov V.SSSGQEVQSSAK.E "sp|P35527|K1C9_HUMAN,tr|K7EQQ3|K7EQQ3_HUMAN" 2 1193.5524 999 137096 3155 2 1193.550393 597.7835 "Keratin, type I cytoskeletal 9 OS=Homo sapiens OX=9606 GN=KRT9 PE=1 SV=3" 5.72 1267.2 - 924550 - - - -1.6899 - 2.253 0.574 - 451.4 1 1 0 -0.002 12 0 0 0 7.79E+06 0.00E+00 - - - 5.4171 0.9936 221125_WJC_METTL3_EV_vs_WT_F10.03165.03165.2 0.00355 16-Sep R.QQITEKEEK.T sp|P12270|TPR_HUMAN 1 1131.5772 2.96 137104 3165 2 1131.578161 566.7959 Nucleoprotein TPR OS=Homo sapiens OX=9606 GN=TPR PE=1 SV=3 4.79 1268.4 - 434804 - - - 0.8775 - 1.811 0.318 - 385.9 1 2 1 0.001 9 0 0 0 6.76E+06 2.28E+06 - - - 3.1076 1 221125_WJC_METTL3_EV_vs_WT_F10.03176.03176.2 0.000508 15/30 R.GGSGGGGGGGGGGYNR.S "sp|P35637|FUS_HUMAN,tr|H3BNZ4|H3BNZ4_HUMAN,tr|H3BPE7|H3BPE7_HUMAN" 3 1222.5075 1.04 137111 3176 2 1222.502857 612.261 RNA-binding protein FUS OS=Homo sapiens OX=9606 GN=FUS PE=1 SV=1 8.75 1269.8 - 453725 - - - -3.8184 - 2.658 0.618 - 635 1 2 0 -0.0047 16 0 0 0 8.37E+06 8.03E+06 - - - 6.0075 1 221125_WJC_METTL3_EV_vs_WT_F10.03178.03178.2 1.52E-08 13/30 R.GGSGGGGGGGGGGYNR[166.11].S "sp|P35637|FUS_HUMAN,tr|H3BNZ4|H3BNZ4_HUMAN,tr|H3BPE7|H3BPE7_HUMAN" 3 1232.5158 1.04 137113 3178 2 1232.511993 617.2652 RNA-binding protein FUS OS=Homo sapiens OX=9606 GN=FUS PE=1 SV=1 8.75 1270.1 - 312990 - - - -3.0847 - 2.936 0.656 - 583.8 1 2 0 -0.0038 16 0 0 0 8.37E+06 8.03E+06 - - - 6.533 0.913 221125_WJC_METTL3_EV_vs_WT_F10.03187.03187.2 0.00121 14-Aug K.DKQTQLNR.G sp|P98175|RBM10_HUMAN 1 1001.5254 1.86 137118 3187 2 1001.522118 501.77 RNA-binding protein 10 OS=Homo sapiens OX=9606 GN=RBM10 PE=1 SV=3 8.75 1271.3 - 618108 - - - -3.284 - 1.792 0.163 - 283.7 1 2 1 -0.0033 8 0 0 0 8.10E+06 4.35E+06 - - - 2.0032 0.9583 221125_WJC_METTL3_EV_vs_WT_F10.03189.03189.2 0.00161 20-Jul K.SEEEQSSSSVK[136.11].K "sp|P07910|HNRPC_HUMAN,tr|B4DY08|B4DY08_HUMAN,tr|G3V5V7|G3V5V7_HUMAN,tr|B2R5W2|B2R5W2_HUMAN,tr|G3V4C1|G3V4C1_HUMAN,tr|G3V2D6|G3V2D6_HUMAN,tr|G3V4W0|G3V4W0_HUMAN,tr|G3V2Q1|G3V2Q1_HUMAN" 8 1203.5346 1.03 137120 3189 2 1203.525708 602.7746 Heterogeneous nuclear ribonucleoproteins C1\C2 OS=Homo sapiens OX=9606 GN=HNRNPC PE=1 SV=4 4.25 1271.5 - 253343 - - - -7.4223 - 1.321 0.454 - 76 1 2 0 -0.0089 11 0 0 0 6.94E+06 6.76E+06 - - - 3.1445 0.9994 221125_WJC_METTL3_EV_vs_WT_F10.03190.03190.2 0.00173 20-Jun R.NDGAENSC[160.03]TER[166.11].D "sp|Q9Y5Q8|TF3C5_HUMAN,tr|Q5T7U1|Q5T7U1_HUMAN,tr|H7BY84|H7BY84_HUMAN" 3 1261.4869 0.44 137121 3190 2 1261.483341 631.7507 General transcription factor 3C polypeptide 5 OS=Homo sapiens OX=9606 GN=GTF3C5 PE=1 SV=2 4.14 1271.7 - 125828 - - - -2.7919 - 1.527 0.577 - 131.5 1 2 0 -0.0035 11 0 0 0 5.47E+05 1.24E+06 - - - 4.4468 0.9492 221125_WJC_METTL3_EV_vs_WT_F10.03193.03193.2 0.882 20-Jun K.TETDKENAEVK.F sp|Q86UP2|KTN1_HUMAN 1 1262.599 2.21 137122 3193 2 1262.598004 632.3068 Kinectin OS=Homo sapiens OX=9606 GN=KTN1 PE=1 SV=1 4.41 1272.1 - 217267 - - - -0.8086 - 1.468 0.154 - 133 1 2 1 -0.001 11 0 0 0 2.94E+06 1.33E+06 - - - 1.2167 0.9997 221125_WJC_METTL3_EV_vs_WT_F10.03195.03195.3 0.00059 Aug-40 K.AC[160.03]QVAHC[160.03]ASSR[166.11].Q sp|Q92793|CBP_HUMAN 1 1255.5425 0.94 137123 3195 3 1255.541129 419.5215 CREB-binding protein OS=Homo sapiens OX=9606 GN=CREBBP PE=1 SV=3 8.12 1272.3 - 517526 - - - -1.127 - 1.774 0.363 - 87 1 2 0 -0.0014 11 0 0 0 5.16E+06 5.50E+06 - - - 4.2152 0.9994 221125_WJC_METTL3_EV_vs_WT_F10.03197.03197.2 0.00422 20-Nov K.SEEEQSSSSVK.K "sp|P07910|HNRPC_HUMAN,tr|B4DY08|B4DY08_HUMAN,tr|G3V5V7|G3V5V7_HUMAN,tr|B2R5W2|B2R5W2_HUMAN,tr|G3V4C1|G3V4C1_HUMAN,tr|G3V2D6|G3V2D6_HUMAN,tr|G3V4W0|G3V4W0_HUMAN,tr|G3V2Q1|G3V2Q1_HUMAN" 8 1195.5204 1.03 137125 3197 2 1195.517037 598.7675 Heterogeneous nuclear ribonucleoproteins C1\C2 OS=Homo sapiens OX=9606 GN=HNRNPC PE=1 SV=4 4.25 1272.6 - 361764 - - - -2.8473 - 2.112 0.459 - 515.2 1 2 0 -0.0034 11 0 0 0 6.94E+06 6.76E+06 - - - 4.4526 0.9998 221125_WJC_METTL3_EV_vs_WT_F10.03203.03203.3 0.00134 Sep-48 K.GVGQANK[136.11]PDETSK[136.11].T sp|Q14966|ZN638_HUMAN 1 1345.6809 0.9 137129 3203 3 1345.679889 449.5676 Zinc finger protein 638 OS=Homo sapiens OX=9606 GN=ZNF638 PE=1 SV=2 6.07 1273.3 - 1.47E+06 - - - -0.7201 - 1.803 0.409 - 63.9 1 2 0 -0.001 13 0 0 0 2.79E+07 3.09E+07 - - - 4.6979 1 221125_WJC_METTL3_EV_vs_WT_F10.03204.03204.3 1.84E-07 14/48 K.GVGQANKPDETSK.T sp|Q14966|ZN638_HUMAN 1 1329.6525 0.9 137130 3204 3 1329.650786 444.2248 Zinc finger protein 638 OS=Homo sapiens OX=9606 GN=ZNF638 PE=1 SV=2 6.07 1273.4 - 938816 - - - -1.2575 - 2.562 0.455 - 173.1 1 2 0 -0.0017 13 0 0 0 2.79E+07 3.09E+07 - - - 6.1631 1 221125_WJC_METTL3_EV_vs_WT_F10.03205.03205.3 9.18E-06 16/44 R.ESSVVQAGGSK[136.11]K[136.11].H sp|Q5W0B1|OBI1_HUMAN 1 1191.643 1.41 137131 3205 3 1191.641968 398.2216 ORC ubiquitin ligase 1 OS=Homo sapiens OX=9606 GN=OBI1 PE=1 SV=1 8.69 1273.5 - 753606 - - - -0.8795 - 2.249 0.497 - 367.9 1 2 0 -0.001 12 0 0 0 5.36E+07 3.80E+07 - - - 6.3273 0.9982 221125_WJC_METTL3_EV_vs_WT_F10.03207.03207.2 0.000568 18-Oct R.AAK[136.11]DEVSESR[166.11].R sp|P07196|NFL_HUMAN 1 1108.5479 2.21 137133 3207 2 1108.547346 555.2812 Neurofilament light polypeptide OS=Homo sapiens OX=9606 GN=NEFL PE=1 SV=3 4.68 1273.7 - 438105 - - - -0.5331 - 1.981 0.476 - 304.5 1 2 1 -0.0006 10 0 0 0 1.38E+07 6.24E+06 - - - 4.4647 0.9998 221125_WJC_METTL3_EV_vs_WT_F10.03212.03212.3 0.00377 Dec-40 K.TETDKENAEVK.F sp|Q86UP2|KTN1_HUMAN 1 1262.599 2.11 137136 3212 3 1262.598325 421.8736 Kinectin OS=Homo sapiens OX=9606 GN=KTN1 PE=1 SV=1 4.41 1274.3 - 2.81E+06 - - - -0.5544 - 2.528 0.431 - 237.9 1 2 1 -0.0007 11 0 0 0 2.91E+07 1.38E+07 - - - 5.9797 0.9998 221125_WJC_METTL3_EV_vs_WT_F10.03214.03214.3 7.49E-06 14/44 K.VQESTKGPDEAK.L "sp|O43390|HNRPR_HUMAN,tr|B4DT28|B4DT28_HUMAN,tr|A0A6Q8PH31|A0A6Q8PH31_HUMAN,tr|A0A6Q8PEX7|A0A6Q8PEX7_HUMAN,tr|A0A6Q8PH35|A0A6Q8PH35_HUMAN" 5 1287.6307 1.45 137138 3214 3 1287.632271 430.2175 Heterogeneous nuclear ribonucleoprotein R OS=Homo sapiens OX=9606 GN=HNRNPR PE=1 SV=1 4.68 1274.5 - 1.09E+06 - - - 1.2511 - 2.521 0.49 - 246.6 1 2 1 0.0016 12 0 0 0 3.13E+08 2.15E+08 - - - 6.5656 0.9999 221125_WJC_METTL3_EV_vs_WT_F10.03217.03217.2 2.24E-06 24-Sep K.GVGQANK[136.11]PDETSK[136.11].T sp|Q14966|ZN638_HUMAN 1 1345.6809 0.79 137141 3217 2 1345.68011 673.8477 Zinc finger protein 638 OS=Homo sapiens OX=9606 GN=ZNF638 PE=1 SV=2 6.07 1274.8 - 148383 - - - -0.5559 - 2.005 0.566 - 294.9 1 2 0 -0.0007 13 0 0 0 1.10E+06 1.39E+06 - - - 5.0066 0.9981 221125_WJC_METTL3_EV_vs_WT_F10.03218.03218.2 0.00638 24-Jul K.GVGQANKPDETSK.T sp|Q14966|ZN638_HUMAN 1 1329.6525 0.79 137142 3218 2 1329.648646 665.8335 Zinc finger protein 638 OS=Homo sapiens OX=9606 GN=ZNF638 PE=1 SV=2 6.07 1275 - 109330 - - - -2.8669 - 1.498 0.407 - 139.8 1 2 0 -0.0038 13 0 0 0 1.10E+06 1.39E+06 - - - 3.0831 0.9886 221125_WJC_METTL3_EV_vs_WT_F10.03219.03219.2 0.0455 22-Jun K.VQESTKGPDEAK.L "sp|O43390|HNRPR_HUMAN,tr|B4DT28|B4DT28_HUMAN,tr|A0A6Q8PH31|A0A6Q8PH31_HUMAN,tr|A0A6Q8PEX7|A0A6Q8PEX7_HUMAN,tr|A0A6Q8PH35|A0A6Q8PH35_HUMAN" 5 1287.6307 1.49 137143 3219 2 1287.629641 644.8226 Heterogeneous nuclear ribonucleoprotein R OS=Homo sapiens OX=9606 GN=HNRNPR PE=1 SV=1 4.68 1275.1 - 58709.1 - - - -0.7914 - 1.449 0.328 - 129 1 2 1 -0.001 12 0 0 0 2.31E+07 1.55E+07 - - - 2.4391 0.9991 221125_WJC_METTL3_EV_vs_WT_F10.03226.03226.2 0.0108 16-Aug K.HTSISESSR[166.11].Q sp|P46939|UTRN_HUMAN 1 1012.4813 1.65 137148 3226 2 1012.480472 507.2479 Utrophin OS=Homo sapiens OX=9606 GN=UTRN PE=1 SV=2 6.75 1276 - 369573 - - - -0.8247 - 1.542 0.306 - 156.4 1 2 0 -0.0008 9 0 0 0 9.06E+06 5.49E+06 - - - 2.5538 0.928 221125_WJC_METTL3_EV_vs_WT_F10.03230.03230.2 0.39 12-Jun R.DR[166.11]ENYDR[166.11].G "sp|P17844|DDX5_HUMAN,tr|J3KTA4|J3KTA4_HUMAN,tr|A0A0G2JLI4|A0A0G2JLI4_HUMAN" 3 986.4321 1.75 137152 3230 2 986.433006 494.2233 Probable ATP-dependent RNA helicase DDX5 OS=Homo sapiens OX=9606 GN=DDX5 PE=1 SV=1 4.56 1276.5 - 161714 - - - 0.957 - 1.203 0.194 - 131 1 2 1 0.0009 7 0 0 0 1.28E+07 7.34E+06 - - - 1.0592 0.9424 221125_WJC_METTL3_EV_vs_WT_F10.03231.03231.2 0.0295 16-Jun K.ALKVEDKEK.E sp|Q5JSZ5|PRC2B_HUMAN 1 1058.5972 2.39 137153 3231 2 1058.596063 530.3059 Protein PRRC2B OS=Homo sapiens OX=9606 GN=PRRC2B PE=1 SV=2 6.22 1276.7 - 87691.4 - - - -1.0504 - 1.245 0.205 - 85.7 1 2 2 -0.0011 9 0 0 0 1.01E+06 4.20E+05 - - - 1.1888 0.9926 221125_WJC_METTL3_EV_vs_WT_F10.03234.03234.2 0.121 12-Aug R.DRENYDR.G "sp|P17844|DDX5_HUMAN,tr|J3KTA4|J3KTA4_HUMAN,tr|A0A0G2JLI4|A0A0G2JLI4_HUMAN" 3 966.4155 1.75 137154 3234 2 966.415368 484.215 Probable ATP-dependent RNA helicase DDX5 OS=Homo sapiens OX=9606 GN=DDX5 PE=1 SV=1 4.56 1277.1 - 704624 - - - -0.1594 - 1.554 0.312 - 217.9 1 2 1 -0.0002 7 0 0 0 1.28E+07 7.34E+06 - - - 2.7422 0.9996 221125_WJC_METTL3_EV_vs_WT_F10.03237.03237.2 0.000169 18-Aug K.THSVPSATSK.G "sp|Q6ULP2|AFTIN_HUMAN,tr|A0A0U1RR74|A0A0U1RR74_HUMAN,tr|B8ZZI9|B8ZZI9_HUMAN" 3 1013.5142 1.71 137157 3237 2 1013.514355 507.7644 Aftiphilin OS=Homo sapiens OX=9606 GN=AFTPH PE=1 SV=3 8.44 1277.4 - 392406 - - - 0.1786 - 1.484 0.431 - 212.2 1 2 0 0.0002 10 0 0 0 2.00E+07 1.17E+07 - - - 3.3262 0.8327 221125_WJC_METTL3_EV_vs_WT_F10.03241.03241.2 0.52 18-Mar R.SGGGGYSQNR[166.11].W "sp|Q9BUJ2|HNRL1_HUMAN,tr|A0A0A0MRA5|A0A0A0MRA5_HUMAN,tr|M0R3F1|M0R3F1_HUMAN,tr|B7Z4B8|B7Z4B8_HUMAN" 4 991.4347 1.25 137161 3241 2 991.43657 496.7246 Heterogeneous nuclear ribonucleoprotein U-like protein 1 OS=Homo sapiens OX=9606 GN=HNRNPUL1 PE=1 SV=2 8.46 1277.9 - 169986 - - - 1.8952 - 0.881 0.141 - 23.5 14 2 0 0.0019 10 0 0 0 1.49E+06 1.19E+06 - - - -0.7838 0.9987 221125_WJC_METTL3_EV_vs_WT_F10.03242.03242.2 0.00037 22-Sep K.VQESTK[136.11]GPDEAK[136.11].L "sp|O43390|HNRPR_HUMAN,tr|B4DT28|B4DT28_HUMAN,tr|A0A6Q8PH31|A0A6Q8PH31_HUMAN,tr|A0A6Q8PEX7|A0A6Q8PEX7_HUMAN,tr|A0A6Q8PH35|A0A6Q8PH35_HUMAN" 5 1303.6591 1.49 137162 3242 2 1303.659931 652.8368 Heterogeneous nuclear ribonucleoprotein R OS=Homo sapiens OX=9606 GN=HNRNPR PE=1 SV=1 4.68 1278.1 - 146005 - - - 0.6681 - 2.224 0.541 - 329.9 1 2 1 0.0009 12 0 0 0 2.31E+07 1.55E+07 - - - 5.1397 0.9994 221125_WJC_METTL3_EV_vs_WT_F10.03256.03256.3 0.00327 14/44 K.VQESTK[136.11]GPDEAK[136.11].L "sp|O43390|HNRPR_HUMAN,tr|B4DT28|B4DT28_HUMAN,tr|A0A6Q8PH31|A0A6Q8PH31_HUMAN,tr|A0A6Q8PEX7|A0A6Q8PEX7_HUMAN,tr|A0A6Q8PH35|A0A6Q8PH35_HUMAN" 5 1303.6591 1.45 137172 3256 3 1303.656614 435.5603 Heterogeneous nuclear ribonucleoprotein R OS=Homo sapiens OX=9606 GN=HNRNPR PE=1 SV=1 4.68 1279.8 - 5.30E+06 - - - -1.8763 - 2.446 0.401 - 257.4 1 2 1 -0.0024 12 0 0 0 3.13E+08 2.15E+08 - - - 5.4894 0.9998 221125_WJC_METTL3_EV_vs_WT_F10.03257.03257.2 9.67E-05 14/16 K.RQEAIAQNR.R sp|Q6P2Q9|PRP8_HUMAN 1 1084.5738 1.47 137173 3257 2 1084.571914 543.2942 Pre-mRNA-processing-splicing factor 8 OS=Homo sapiens OX=9606 GN=PRPF8 PE=1 SV=2 9.6 1279.9 - 1.38E+06 - - - -1.6965 - 2.703 0.495 - 342.3 1 2 0 -0.0018 9 0 0 0 2.11E+07 1.44E+07 - - - 5.5732 0.9997 221125_WJC_METTL3_EV_vs_WT_F10.03258.03258.2 0.000151 14/16 K.R[166.11]QEAIAQNR[166.11].R sp|Q6P2Q9|PRP8_HUMAN 1 1104.5903 1.47 137174 3258 2 1104.588161 553.3024 Pre-mRNA-processing-splicing factor 8 OS=Homo sapiens OX=9606 GN=PRPF8 PE=1 SV=2 9.6 1280 - 1.10E+06 - - - -1.931 - 2.404 0.401 - 397 1 2 0 -0.0021 9 0 0 0 2.11E+07 1.44E+07 - - - 4.5397 1 221125_WJC_METTL3_EV_vs_WT_F10.03260.03260.3 8.43E-07 15/44 R.SPSHSGNAGDLK.Q "sp|Q9H694|BICC1_HUMAN,tr|A6NGY7|A6NGY7_HUMAN" 2 1168.5473 3.42 137176 3260 3 1168.546873 390.523 Protein bicaudal C homolog 1 OS=Homo sapiens OX=9606 GN=BICC1 PE=1 SV=2 6.46 1280.2 - 664156 - - - -0.3355 - 2.474 0.549 - 281.5 1 2 0 -0.0004 12 0 0 0 1.54E+07 4.51E+06 - - - 7.1715 0.9931 221125_WJC_METTL3_EV_vs_WT_F10.03270.03270.2 0.732 14-Sep K.KEREEEFK.T "sp|Q9NYF8|BCLF1_HUMAN,tr|H0YF63|H0YF63_HUMAN,tr|E9PK91|E9PK91_HUMAN,tr|H0YF14|H0YF14_HUMAN" 4 1093.5404 1.96 137184 3270 2 1093.539862 547.7775 Bcl-2-associated transcription factor 1 OS=Homo sapiens OX=9606 GN=BCLAF1 PE=1 SV=2 4.95 1281.3 - 602965 - - - -0.481 - 1.721 0.292 - 290.3 1 2 1 -0.0005 8 0 0 0 5.93E+06 3.03E+06 - - - 2.8349 0.9985 221125_WJC_METTL3_EV_vs_WT_F10.03281.03281.2 0.00942 16-Jul K.DNTAQQIKK.V sp|P29508|SPB3_HUMAN 1 1044.5564 65.26 137191 3281 2 1044.555404 523.2855 Serpin B3 OS=Homo sapiens OX=9606 GN=SERPINB3 PE=1 SV=2 8.59 1282.8 - 327651 - - - -0.9277 - 1.359 0.3 - 139.3 1 2 0 -0.001 9 0 0 0 3.56E+06 5.45E+04 - - - 2.1439 0.929 221125_WJC_METTL3_EV_vs_WT_F10.03291.03291.3 0.4 Nov-40 K.EGQENGHITTK.S "sp|P11717|MPRI_HUMAN,tr|A0A7I2V657|A0A7I2V657_HUMAN" 2 1212.5735 1.18 137199 3291 3 1212.571077 405.1984 Cation-independent mannose-6-phosphate receptor OS=Homo sapiens OX=9606 GN=IGF2R PE=1 SV=3 5.4 1283.8 - 1.45E+06 - - - -1.9809 - 1.452 0.123 - 145.7 1 2 0 -0.0024 11 0 0 0 1.07E+07 9.10E+06 - - - 0.9701 0.9993 221125_WJC_METTL3_EV_vs_WT_F10.03293.03293.3 0.00135 Oct-40 R.KADGYNQPDSK.R "sp|O60506|HNRPQ_HUMAN,sp|O43390|HNRPR_HUMAN,tr|B4DT28|B4DT28_HUMAN,tr|A0A7I2V2F2|A0A7I2V2F2_HUMAN,tr|A0A7I2V309|A0A7I2V309_HUMAN,tr|A0A6Q8PH35|A0A6Q8PH35_HUMAN" 6 1221.5626 1.58 137201 3293 3 1221.55658 408.1948 Heterogeneous nuclear ribonucleoprotein Q OS=Homo sapiens OX=9606 GN=SYNCRIP PE=1 SV=2 5.96 1283.9 - 1.58E+06 - - - -4.9117 - 2.125 0.475 - 168.8 1 2 0 -0.006 11 0 0 0 2.49E+07 1.58E+07 - - - 5.9755 0.9876 221125_WJC_METTL3_EV_vs_WT_F10.03294.03294.2 0.000361 22-Oct F.SSSSGYGGGSSR.V sp|P35527|K1C9_HUMAN 1 1087.453 1125.28 137202 3294 2 1087.452236 544.7338 "Keratin, type I cytoskeletal 9 OS=Homo sapiens OX=9606 GN=KRT9 PE=1 SV=3" 8.46 1284 - 751044 - - - -0.7301 - 1.902 0.46 - 369.1 1 1 0 -0.0008 12 0 0 0 4.36E+07 3.88E+04 - - - 4.1299 0.9999 221125_WJC_METTL3_EV_vs_WT_F10.03298.03298.2 2.57E-05 13/20 R.KADGYNQPDSK.R "sp|O60506|HNRPQ_HUMAN,sp|O43390|HNRPR_HUMAN,tr|B4DT28|B4DT28_HUMAN,tr|A0A7I2V2F2|A0A7I2V2F2_HUMAN,tr|A0A7I2V309|A0A7I2V309_HUMAN,tr|A0A6Q8PH35|A0A6Q8PH35_HUMAN" 6 1221.5626 1.92 137206 3298 2 1221.562316 611.7886 Heterogeneous nuclear ribonucleoprotein Q OS=Homo sapiens OX=9606 GN=SYNCRIP PE=1 SV=2 5.96 1284.5 - 412183 - - - -0.2161 - 2.291 0.54 - 556.5 1 2 0 -0.0003 11 0 0 0 5.52E+06 2.88E+06 - - - 5.272 0.9996 221125_WJC_METTL3_EV_vs_WT_F10.03299.03299.2 2.00E-07 20-Oct R.K[136.11]ADGYNQPDSK[136.11].R "sp|O60506|HNRPQ_HUMAN,sp|O43390|HNRPR_HUMAN,tr|B4DT28|B4DT28_HUMAN,tr|A0A7I2V2F2|A0A7I2V2F2_HUMAN,tr|A0A7I2V309|A0A7I2V309_HUMAN,tr|A0A6Q8PH35|A0A6Q8PH35_HUMAN" 6 1237.591 1.92 137207 3299 2 1237.587372 619.8028 Heterogeneous nuclear ribonucleoprotein Q OS=Homo sapiens OX=9606 GN=SYNCRIP PE=1 SV=2 5.96 1284.6 - 367423 - - - -2.9153 - 2.248 0.599 - 313.4 1 2 0 -0.0036 11 0 0 0 5.52E+06 2.88E+06 - - - 5.6554 0.8112 221125_WJC_METTL3_EV_vs_WT_F10.03300.03300.2 0.00258 18-Aug Q.ESTKGPDEAK.L "sp|O43390|HNRPR_HUMAN,tr|B4DT28|B4DT28_HUMAN,tr|A0A6Q8PH31|A0A6Q8PH31_HUMAN,tr|A0A6Q8PEX7|A0A6Q8PEX7_HUMAN,tr|A0A6Q8PH35|A0A6Q8PH35_HUMAN" 5 1060.5037 0.53 137208 3300 2 1060.502674 531.2591 Heterogeneous nuclear ribonucleoprotein R OS=Homo sapiens OX=9606 GN=HNRNPR PE=1 SV=1 4.68 1284.8 - 343274 - - - -0.9373 - 1.564 0.447 - 181.6 1 1 1 -0.001 10 0 0 0 4.02E+06 7.62E+06 - - - 3.5906 0.9997 221125_WJC_METTL3_EV_vs_WT_F10.03302.03302.2 1.34E-07 30-Dec K.ASGGQDGAASSAGAAK[136.11].R sp|O60287|NPA1P_HUMAN 1 1312.6099 0.87 137210 3302 2 1312.606368 657.3122 Nucleolar pre-ribosomal-associated protein 1 OS=Homo sapiens OX=9606 GN=URB1 PE=1 SV=4 5.88 1285 - 200427 - - - -2.6687 - 2.61 0.546 - 382.7 1 2 0 -0.0035 16 0 0 0 2.09E+06 2.39E+06 - - - 5.4313 0.9458 221125_WJC_METTL3_EV_vs_WT_F10.03309.03309.3 0.0403 13/40 K.PAPPKPEPKPK.K sp|P05204|HMGN2_HUMAN 1 1184.6917 0.81 137215 3309 3 1184.690655 395.9045 Non-histone chromosomal protein HMG-17 OS=Homo sapiens OX=9606 GN=HMGN2 PE=1 SV=3 9.73 1285.9 - 1.61E+06 - - - -0.9192 - 2.051 0.285 - 231.2 1 1 0 -0.0011 11 0 0 0 1.82E+07 2.25E+07 - - - 3.7578 0.9946 221125_WJC_METTL3_EV_vs_WT_F10.03311.03311.3 6.73E-06 15/36 R.RGMDDDRGPR.R "sp|Q14152|EIF3A_HUMAN,sp|Q14152|EIF3A_HUMAN,sp|Q14152|EIF3A_HUMAN" 3 1173.5309 13.02 137217 3311 3 1173.530897 392.1842 Eukaryotic translation initiation factor 3 subunit A OS=Homo sapiens OX=9606 GN=EIF3A PE=1 SV=1 6.04 1286 - 733733 - - - -0.0051 - 2.376 0.191 - 374.1 1 2 1 0 10 0 0 0 9.01E+06 6.92E+05 - - - 3.1969 0.9998 221125_WJC_METTL3_EV_vs_WT_F10.03313.03313.2 7.06E-05 16-Oct K.SYSEHDDER[166.11].V "sp|Q9UBU9|NXF1_HUMAN,tr|E9PQA4|E9PQA4_HUMAN" 2 1146.4453 0.88 137219 3313 2 1146.444126 574.2299 Nuclear RNA export factor 1 OS=Homo sapiens OX=9606 GN=NXF1 PE=1 SV=1 4.31 1286.3 - 467994 - - - -1.0371 - 1.747 0.539 - 344.7 1 2 0 -0.0012 9 0 0 0 3.38E+06 3.85E+06 - - - 4.6357 0.9998 221125_WJC_METTL3_EV_vs_WT_F10.03314.03314.2 9.46E-07 20-Oct K.SSQAEAC[160.03]SESR.N "sp|Q9NZJ0|DTL_HUMAN,tr|F5GZ90|F5GZ90_HUMAN" 2 1210.4884 0.73 137220 3314 2 1210.486446 606.2515 Denticleless protein homolog OS=Homo sapiens OX=9606 GN=DTL PE=1 SV=3 4.53 1286.4 - 415232 - - - -1.6382 - 2.013 0.594 - 440.1 1 2 0 -0.002 11 0 0 0 2.40E+06 3.30E+06 - - - 5.3203 0.9115 221125_WJC_METTL3_EV_vs_WT_F10.03321.03321.2 1.07 16-Sep G.KPESEGEAK.E "sp|Q96EI5|TCAL4_HUMAN,tr|D6RD44|D6RD44_HUMAN,tr|D6RCE9|D6RCE9_HUMAN,tr|D6RIH3|D6RIH3_HUMAN" 4 973.4716 12.71 137224 3321 2 973.470002 487.7431 Transcription elongation factor A protein-like 4 OS=Homo sapiens OX=9606 GN=TCEAL4 PE=1 SV=2 4.79 1287.4 - 665433 - - - -1.6826 - 1.912 0.206 - 194.3 1 1 0 -0.0016 9 0 0 0 3.66E+06 2.88E+05 - - - 2.4371 0.9921 221125_WJC_METTL3_EV_vs_WT_F10.03325.03325.2 0.000232 14-Jul S.YSEHDDER.V "sp|Q9UBU9|NXF1_HUMAN,tr|E9PQA4|E9PQA4_HUMAN" 2 1049.405 1.32 137228 3325 2 1049.40403 525.7098 Nuclear RNA export factor 1 OS=Homo sapiens OX=9606 GN=NXF1 PE=1 SV=1 4.31 1287.9 - 223146 - - - -0.9405 - 1.678 0.592 - 203.1 1 1 0 -0.001 8 0 0 0 8.30E+05 6.30E+05 - - - 4.9743 0.9978 221125_WJC_METTL3_EV_vs_WT_F10.03328.03328.3 3.93E-06 13/32 K.SYSEHDDER.V "sp|Q9UBU9|NXF1_HUMAN,tr|E9PQA4|E9PQA4_HUMAN" 2 1136.437 0.03 137229 3328 3 1137.438084 379.8196 Nuclear RNA export factor 1 OS=Homo sapiens OX=9606 GN=NXF1 PE=1 SV=1 4.31 1288.3 - 530920 - - - 880.8574 - 2.177 0.497 - 263.2 1 2 0 1.001 9 0 0 0 8.66E+05 2.50E+07 - - - 6.1483 0.9199 221125_WJC_METTL3_EV_vs_WT_F10.03329.03329.2 0.000135 22-Aug R.HGSGSGQSSSYG.P "sp|Q86YZ3|HORN_HUMAN,sp|Q86YZ3|HORN_HUMAN,sp|Q86YZ3|HORN_HUMAN" 3 1109.4374 - 137230 3329 2 1109.434925 555.726 Hornerin OS=Homo sapiens OX=9606 GN=HRNR PE=1 SV=2 6.74 1288.4 - 447219 - - - -2.2128 - 1.276 0.433 - 107 1 1 0 -0.0025 12 0 0 0 - - - - - 2.8797 0.9999 221125_WJC_METTL3_EV_vs_WT_F10.03340.03340.3 0.000231 13/52 K.VAGGAAPSKPASAK.K "sp|Q14978|NOLC1_HUMAN,tr|A0A0A0MRM9|A0A0A0MRM9_HUMAN" 2 1210.667 2.31 137239 3340 3 1210.665793 404.5629 Nucleolar and coiled-body phosphoprotein 1 OS=Homo sapiens OX=9606 GN=NOLC1 PE=1 SV=2 10 1289.6 - 1.93E+06 - - - -0.9854 - 2.385 0.421 - 210.9 1 2 0 -0.0012 14 0 0 0 6.03E+07 2.61E+07 - - - 5.5433 0.9998 221125_WJC_METTL3_EV_vs_WT_F10.03341.03341.3 0.00553 Oct-40 R.K[136.11]VQSGNINAAK[136.11].T "sp|P49368|TCPG_HUMAN,tr|E9PM09|E9PM09_HUMAN,tr|Q5SZW8|Q5SZW8_HUMAN,tr|E9PRC8|E9PRC8_HUMAN,tr|Q5SZX9|Q5SZX9_HUMAN,tr|Q5SZX6|Q5SZX6_HUMAN" 6 1144.6535 0.001 137240 3341 3 1144.652863 382.5585 T-complex protein 1 subunit gamma OS=Homo sapiens OX=9606 GN=CCT3 PE=1 SV=4 10 1289.7 - 1.75E+06 - - - -0.5748 - 2.241 0.319 - 158.5 1 2 0 -0.0007 11 0 0 0 0.00E+00 6.18E+07 - - - 4.3887 0.9998 221125_WJC_METTL3_EV_vs_WT_F10.03343.03343.3 0.0013 Nov-44 K.LAEAHQQEC[160.03]C[160.03]QK[136.11].F "sp|Q9Y5X3|SNX5_HUMAN,tr|A0A087WUY5|A0A087WUY5_HUMAN" 2 1508.6591 1.26 137242 3343 3 1508.658493 503.8937 Sorting nexin-5 OS=Homo sapiens OX=9606 GN=SNX5 PE=1 SV=1 5.4 1289.9 - 966687 - - - -0.4335 - 1.935 0.369 - 189 1 2 0 -0.0007 12 0 0 0 5.68E+06 4.49E+06 - - - 4.4835 1 221125_WJC_METTL3_EV_vs_WT_F10.03344.03344.2 6.19E-05 17/20 R.K[136.11]VQSGNINAAK[136.11].T "sp|P49368|TCPG_HUMAN,tr|E9PM09|E9PM09_HUMAN,tr|Q5SZW8|Q5SZW8_HUMAN,tr|E9PRC8|E9PRC8_HUMAN,tr|Q5SZX9|Q5SZX9_HUMAN,tr|Q5SZX6|Q5SZX6_HUMAN" 6 1144.6535 0.25 137243 3344 2 1144.653058 573.334 T-complex protein 1 subunit gamma OS=Homo sapiens OX=9606 GN=CCT3 PE=1 SV=4 10 1290 - 581251 - - - -0.4045 - 3.359 0.539 - 830.9 1 2 0 -0.0005 11 0 0 0 6.60E+06 2.64E+07 - - - 6.2997 0.9999 221125_WJC_METTL3_EV_vs_WT_F10.03348.03348.2 0.000212 26-Dec K.VAGGAAPSKPASAK.K "sp|Q14978|NOLC1_HUMAN,tr|A0A0A0MRM9|A0A0A0MRM9_HUMAN" 2 1210.667 2.79 137247 3348 2 1210.667645 606.3408 Nucleolar and coiled-body phosphoprotein 1 OS=Homo sapiens OX=9606 GN=NOLC1 PE=1 SV=2 10 1290.5 - 187539 - - - 0.5443 - 2.213 0.502 - 393.4 1 2 0 0.0007 14 0 0 0 6.59E+06 2.36E+06 - - - 4.7419 0.9999 221125_WJC_METTL3_EV_vs_WT_F10.03351.03351.2 8.57E-05 18-Nov R.QAQQAQNVQR[166.11].K "sp|Q9NQ55|SSF1_HUMAN,tr|A0A0B4J1V8|A0A0B4J1V8_HUMAN,tr|H7C446|H7C446_HUMAN,tr|A0A0A6YYI3|A0A0A6YYI3_HUMAN,tr|A8MV53|A8MV53_HUMAN" 5 1179.5984 -1 137250 3351 2 1179.59913 590.8065 Suppressor of SWI4 1 homolog OS=Homo sapiens OX=9606 GN=PPAN PE=2 SV=1 9.75 1290.9 - 82992 - - - 0.6172 - 2.114 0.496 - 513.2 1 2 0 0.0007 10 0 0 0 0.00E+00 0.00E+00 - - - 4.7937 0.9984 221125_WJC_METTL3_EV_vs_WT_F10.03355.03355.3 0.0214 Sep-40 K.IQNNDNVGK[136.11]PK[136.11].S "sp|Q08170|SRSF4_HUMAN,tr|A0A0D9SEM4|A0A0D9SEM4_HUMAN" 2 1241.6699 1.59 137252 3355 3 1241.667377 414.8972 Serine\arginine-rich splicing factor 4 OS=Homo sapiens OX=9606 GN=SRSF4 PE=1 SV=2 8.59 1291.5 - 4.77E+06 - - - -2.0311 - 1.438 0.343 - 101.2 1 2 0 -0.0025 11 0 0 0 3.14E+07 1.98E+07 - - - 3.3954 0.9999 221125_WJC_METTL3_EV_vs_WT_F10.03359.03359.3 0.304 15/44 K.RPGSVSSTDQER.E sp|Q9H1B7|I2BPL_HUMAN 1 1317.6273 1.75 137256 3359 3 1317.62487 440.2164 Probable E3 ubiquitin-protein ligase IRF2BPL OS=Homo sapiens OX=9606 GN=IRF2BPL PE=1 SV=1 6.07 1291.7 - 1.71E+06 - - - -1.8488 - 2.792 0.43 - 562.1 1 2 0 -0.0024 12 0 0 0 1.39E+07 7.95E+06 - - - 6.1794 1 221125_WJC_METTL3_EV_vs_WT_F10.03361.03361.3 1.16E-05 15/44 K.R[166.11]PGSVSSTDQER[166.11].E sp|Q9H1B7|I2BPL_HUMAN 1 1337.6438 1.77 137258 3361 3 1337.641884 446.8886 Probable E3 ubiquitin-protein ligase IRF2BPL OS=Homo sapiens OX=9606 GN=IRF2BPL PE=1 SV=1 6.07 1291.9 - 1.30E+06 - - - -1.4668 - 3.028 0.541 - 450.4 1 2 0 -0.002 12 0 0 0 1.44E+07 8.16E+06 - - - 7.642 0.9999 221125_WJC_METTL3_EV_vs_WT_F10.03362.03362.2 2.53E-05 16/20 R.KVQSGNINAAK.T "sp|P49368|TCPG_HUMAN,tr|E9PM09|E9PM09_HUMAN,tr|Q5SZW8|Q5SZW8_HUMAN,tr|E9PRC8|E9PRC8_HUMAN,tr|Q5SZX9|Q5SZX9_HUMAN,tr|Q5SZX6|Q5SZX6_HUMAN" 6 1128.6251 0.25 137259 3362 2 1128.62425 565.3198 T-complex protein 1 subunit gamma OS=Homo sapiens OX=9606 GN=CCT3 PE=1 SV=4 10 1292 - 1.20E+06 - - - -0.7717 - 2.704 0.434 - 739.5 1 2 0 -0.0009 11 0 0 0 6.60E+06 2.64E+07 - - - 4.9372 1 221125_WJC_METTL3_EV_vs_WT_F10.03365.03365.2 2.06E-07 13/22 R.EESTSSGNVSNR.K "sp|P23193|TCEA1_HUMAN,tr|A0A1W2PRL9|A0A1W2PRL9_HUMAN,tr|A0A1W2PPZ5|A0A1W2PPZ5_HUMAN" 3 1265.5484 1.38 137262 3365 2 1265.546552 633.7815 Transcription elongation factor A protein 1 OS=Homo sapiens OX=9606 GN=TCEA1 PE=1 SV=2 4.53 1292.3 - 1.11E+06 - - - -1.45 - 2.499 0.666 - 803.7 1 2 0 -0.0018 12 0 0 0 2.35E+07 1.70E+07 - - - 6.3694 1 221125_WJC_METTL3_EV_vs_WT_F10.03367.03367.2 1.91E-07 14/22 R.EESTSSGNVSNR[166.11].K "sp|P23193|TCEA1_HUMAN,tr|A0A1W2PRL9|A0A1W2PRL9_HUMAN,tr|A0A1W2PPZ5|A0A1W2PPZ5_HUMAN" 3 1275.5567 1.38 137264 3367 2 1275.555067 638.7856 Transcription elongation factor A protein 1 OS=Homo sapiens OX=9606 GN=TCEA1 PE=1 SV=2 4.53 1292.5 - 956784 - - - -1.2465 - 2.699 0.62 - 944.7 1 2 0 -0.0016 12 0 0 0 2.35E+07 1.70E+07 - - - 6.2323 0.9998 221125_WJC_METTL3_EV_vs_WT_F10.03379.03379.2 0.000925 22-Nov K.ALQQQQQQQQQK.L "sp|Q6Y7W6|GGYF2_HUMAN,tr|A0A7I2V3H7|A0A7I2V3H7_HUMAN,tr|I1E4Y6|I1E4Y6_HUMAN,tr|A0A7I2V516|A0A7I2V516_HUMAN,tr|A0A7I2V3H0|A0A7I2V3H0_HUMAN,tr|A0A7I2V361|A0A7I2V361_HUMAN" 6 1482.7539 2.66 137275 3379 2 1482.752031 742.3842 GRB10-interacting GYF protein 2 OS=Homo sapiens OX=9606 GN=GIGYF2 PE=1 SV=1 8.8 1293.7 - 6.19E+06 - - - -1.2625 - 2.378 0.396 - 478.6 1 2 0 -0.0019 12 0 0 0 8.71E+07 3.27E+07 - - - 4.2445 0.9998 221125_WJC_METTL3_EV_vs_WT_F10.03381.03381.2 0.00642 13/22 K.ALQQQQQQQQQK[136.11].L "sp|Q6Y7W6|GGYF2_HUMAN,tr|A0A7I2V3H7|A0A7I2V3H7_HUMAN,tr|I1E4Y6|I1E4Y6_HUMAN,tr|A0A7I2V516|A0A7I2V516_HUMAN,tr|A0A7I2V3H0|A0A7I2V3H0_HUMAN,tr|A0A7I2V361|A0A7I2V361_HUMAN" 6 1490.7681 2.66 137277 3381 2 1490.766098 746.3913 GRB10-interacting GYF protein 2 OS=Homo sapiens OX=9606 GN=GIGYF2 PE=1 SV=1 8.8 1293.8 - 2.72E+06 - - - -1.3449 - 2.738 0.388 - 701.7 1 2 0 -0.002 12 0 0 0 8.71E+07 3.27E+07 - - - 4.5563 0.9969 221125_WJC_METTL3_EV_vs_WT_F10.03382.03382.3 0.0907 Oct-44 K.ALQQQQQQQQQK[136.11].L "sp|Q6Y7W6|GGYF2_HUMAN,tr|A0A7I2V3H7|A0A7I2V3H7_HUMAN,tr|I1E4Y6|I1E4Y6_HUMAN,tr|A0A7I2V516|A0A7I2V516_HUMAN,tr|A0A7I2V3H0|A0A7I2V3H0_HUMAN,tr|A0A7I2V361|A0A7I2V361_HUMAN" 6 1490.7681 2.7 137278 3382 3 1490.765975 497.93 GRB10-interacting GYF protein 2 OS=Homo sapiens OX=9606 GN=GIGYF2 PE=1 SV=1 8.8 1293.9 - 1.60E+06 - - - -1.4275 - 1.52 0.268 - 83.5 1 2 0 -0.0021 12 0 0 0 4.58E+07 1.70E+07 - - - 2.6879 0.9994 221125_WJC_METTL3_EV_vs_WT_F10.03389.03389.2 0.000442 26-Oct K.VAGGAAPSK[136.11]PASAK[136.11].K "sp|Q14978|NOLC1_HUMAN,tr|A0A0A0MRM9|A0A0A0MRM9_HUMAN" 2 1226.6954 2.79 137285 3389 2 1226.693483 614.355 Nucleolar and coiled-body phosphoprotein 1 OS=Homo sapiens OX=9606 GN=NOLC1 PE=1 SV=2 10 1294.4 - 624332 - - - -1.5513 - 1.774 0.39 - 129.4 1 2 0 -0.0019 14 0 0 0 6.59E+06 2.36E+06 - - - 3.3595 0.9996 221125_WJC_METTL3_EV_vs_WT_F10.03395.03395.2 0.000162 14-Sep K.YDDYHHER.W "tr|H7C561|H7C561_HUMAN,tr|H7C0N4|H7C0N4_HUMAN" 2 1133.4526 -1 137291 3395 2 1133.449221 567.7336 Splicing factor 1 (Fragment) OS=Homo sapiens OX=9606 GN=SF1 PE=1 SV=8 5.21 1295.2 - 285412 - - - -3.0129 - 1.808 0.651 - 310.7 1 2 0 -0.0034 8 0 0 0 0.00E+00 0.00E+00 - - - 5.6343 0.9999 221125_WJC_METTL3_EV_vs_WT_F10.03401.03401.3 2.60E-05 Oct-52 K.VAGGAAPSK[136.11]PASAK[136.11].K "sp|Q14978|NOLC1_HUMAN,tr|A0A0A0MRM9|A0A0A0MRM9_HUMAN" 2 1226.6954 2.31 137296 3401 3 1226.692804 409.9057 Nucleolar and coiled-body phosphoprotein 1 OS=Homo sapiens OX=9606 GN=NOLC1 PE=1 SV=2 10 1295.8 - 5.18E+06 - - - -2.1048 - 2.144 0.486 - 116.4 1 2 0 -0.0026 14 0 0 0 6.04E+07 2.61E+07 - - - 5.9845 0.9929 221125_WJC_METTL3_EV_vs_WT_F10.03407.03407.2 0.00011 13/26 F.GTAVANSNTGSGSR[166.11].R "sp|Q14671|PUM1_HUMAN,tr|Q5T1Z8|Q5T1Z8_HUMAN,tr|H0YDK8|H0YDK8_HUMAN,tr|Q5T1Z4|Q5T1Z4_HUMAN,tr|E9PR38|E9PR38_HUMAN" 5 1287.6043 -1 137302 3407 2 1287.604119 644.8094 Pumilio homolog 1 OS=Homo sapiens OX=9606 GN=PUM1 PE=1 SV=3 9.75 1296.4 - 541642 - - - -0.1219 - 2.217 0.518 - 508.4 1 1 0 -0.0002 14 0 0 0 0.00E+00 0.00E+00 - - - 4.8648 0.9959 221125_WJC_METTL3_EV_vs_WT_F10.03409.03409.2 0.000657 20-Sep R.TKGEPAPPPGK.A "sp|Q86VM9|ZCH18_HUMAN,tr|E7ERS3|E7ERS3_HUMAN" 2 1077.5819 0.73 137304 3409 2 1077.580931 539.7982 Zinc finger CCCH domain-containing protein 18 OS=Homo sapiens OX=9606 GN=ZC3H18 PE=1 SV=2 8.26 1296.7 - 248724 - - - -0.8612 - 1.743 0.398 - 194.2 1 2 1 -0.0009 11 0 0 0 1.00E+06 1.38E+06 - - - 3.4834 0.9936 221125_WJC_METTL3_EV_vs_WT_F10.03424.03424.3 9.19E-06 16/48 F.SSGSAVVSGGSRR.S sp|P35908|K22E_HUMAN 1 1205.6113 1.7 137315 3424 3 1205.608566 402.8777 "Keratin, type II cytoskeletal 2 epidermal OS=Homo sapiens OX=9606 GN=KRT2 PE=1 SV=2" 12 1298.5 - 2.33E+06 - - - -2.2362 - 2.655 0.483 - 448.6 1 1 0 -0.0027 13 0 0 0 1.53E+07 8.99E+06 - - - 6.5717 0.9999 221125_WJC_METTL3_EV_vs_WT_F10.03427.03427.2 0.00426 14/16 K.HGLAHDEMK.S "sp|Q9Y2W1|TR150_HUMAN,tr|A0A3B3ITZ9|A0A3B3ITZ9_HUMAN" 2 1036.476 1.72 137318 3427 2 1036.475627 519.2453 Thyroid hormone receptor-associated protein 3 OS=Homo sapiens OX=9606 GN=THRAP3 PE=1 SV=2 5.99 1298.7 - 1.12E+06 - - - -0.3734 - 2.373 0.444 - 611.4 1 2 0 -0.0004 9 0 0 0 1.23E+07 7.15E+06 - - - 4.8203 1 221125_WJC_METTL3_EV_vs_WT_F10.03429.03429.2 7.82E-11 19/32 Y.GSGGGSYGSGGGGGGGR.G sp|P04264|K2C1_HUMAN 1 1282.5287 999 137320 3429 2 1282.525457 642.2716 "Keratin, type II cytoskeletal 1 OS=Homo sapiens OX=9606 GN=KRT1 PE=1 SV=6" 8.75 1299 - 984536 - - - -2.4927 - 3.612 0.627 - 863.6 1 1 0 -0.0032 17 0 0 0 8.19E+06 0.00E+00 - - - 6.8284 0.9997 221125_WJC_METTL3_EV_vs_WT_F10.03430.03430.2 0.00618 16-Sep K.QHIC[160.03]DEC[160.03]GK.H sp|P17028|ZNF24_HUMAN 1 1145.4594 0.51 137321 3430 2 1145.459707 573.737 Zinc finger protein 24 OS=Homo sapiens OX=9606 GN=ZNF24 PE=1 SV=4 5.32 1299.1 - 293420 - - - 0.2872 - 1.543 0.452 - 336.5 1 2 0 0.0003 9 0 0 0 2.74E+06 5.39E+06 - - - 3.6342 0.9918 221125_WJC_METTL3_EV_vs_WT_F10.03436.03436.2 2.71E-05 20-Oct R.HGSGSGQSSSY.G "sp|Q86YZ3|HORN_HUMAN,sp|Q86YZ3|HORN_HUMAN,sp|Q86YZ3|HORN_HUMAN,sp|Q86YZ3|HORN_HUMAN,sp|Q86YZ3|HORN_HUMAN" 5 1052.4159 - 137325 3436 2 1052.415936 527.2152 Hornerin OS=Homo sapiens OX=9606 GN=HRNR PE=1 SV=2 6.74 1299.9 - 1.67E+06 - - - 0.019 - 1.653 0.573 - 320.7 1 1 0 0 11 0 0 0 - - - - - 4.6328 0.8597 221125_WJC_METTL3_EV_vs_WT_F10.03440.03440.3 0.65 Aug-40 K.LQGKPQSHELK.V sp|Q8IVD9|NUDC3_HUMAN 1 1263.6935 1.15 137329 3440 3 1263.692512 422.2385 NudC domain-containing protein 3 OS=Homo sapiens OX=9606 GN=NUDCD3 PE=1 SV=3 8.6 1300.3 - 790828 - - - -0.8095 - 1.604 0.032 - 71 1 2 0 -0.001 11 0 0 0 4.43E+06 3.86E+06 - - - 0.2388 0.9002 221125_WJC_METTL3_EV_vs_WT_F10.03442.03442.2 0.0111 24-Aug F.SSGSAVVSGGSRR.S sp|P35908|K22E_HUMAN 1 1205.6113 999 137331 3442 2 1205.610679 603.8129 "Keratin, type II cytoskeletal 2 epidermal OS=Homo sapiens OX=9606 GN=KRT2 PE=1 SV=2" 12 1300.6 - 435165 - - - -0.4836 - 1.416 0.263 - 52.7 1 1 0 -0.0006 13 0 0 0 2.45E+06 0.00E+00 - - - 1.8761 0.9998 221125_WJC_METTL3_EV_vs_WT_F10.03448.03448.2 1.48E-05 18-Aug K.NNQESDC[160.03]VSK[136.11].K "sp|A6NDG6|PGP_HUMAN,tr|H3BV17|H3BV17_HUMAN" 2 1187.4968 1.23 137337 3448 2 1187.496295 594.7557 Glycerol-3-phosphate phosphatase OS=Homo sapiens OX=9606 GN=PGP PE=1 SV=1 4.37 1301.3 - 186620 - - - -0.4387 - 1.888 0.412 - 277.6 1 2 0 -0.0005 10 0 0 0 2.57E+06 2.10E+06 - - - 3.8578 0.9998 221125_WJC_METTL3_EV_vs_WT_F10.03452.03452.3 0.000754 15/44 K.QALANANQDKEK.L sp|Q6BDS2|URFB1_HUMAN 1 1328.6684 1.54 137339 3452 3 1328.668894 443.8968 UHRF1-binding protein 1 OS=Homo sapiens OX=9606 GN=UHRF1BP1 PE=1 SV=1 6.07 1301.9 - 1.88E+06 - - - 0.3402 - 2.582 0.438 - 460 1 2 1 0.0005 12 0 0 0 7.58E+06 4.92E+06 - - - 6.0524 0.9993 221125_WJC_METTL3_EV_vs_WT_F10.03453.03453.3 0.00167 13/44 K.QALANANQDK[136.11]EK[136.11].L sp|Q6BDS2|URFB1_HUMAN 1 1344.6968 1.64 137340 3453 3 1344.694464 449.2396 UHRF1-binding protein 1 OS=Homo sapiens OX=9606 GN=UHRF1BP1 PE=1 SV=1 6.07 1302 - 1.32E+06 - - - -1.7684 - 2.38 0.384 - 266.9 1 2 1 -0.0024 12 0 0 0 7.47E+06 4.56E+06 - - - 5.224 1 221125_WJC_METTL3_EV_vs_WT_F10.03454.03454.3 0.00197 13/40 R.FGGPVHHQAQR.F sp|Q15717|ELAV1_HUMAN 1 1232.6163 1.67 137341 3454 3 1232.617088 411.8794 ELAV-like protein 1 OS=Homo sapiens OX=9606 GN=ELAVL1 PE=1 SV=2 9.76 1302 - 1.50E+06 - - - 0.649 - 2.517 0.494 - 191.5 1 2 0 0.0008 11 0 0 0 2.57E+08 1.55E+08 - - - 6.6697 0.9998 221125_WJC_METTL3_EV_vs_WT_F10.03455.03455.3 2.42E-06 13/40 R.VRQTQVNEATK.A "sp|Q8WWY3|PRP31_HUMAN,tr|E7EVX8|E7EVX8_HUMAN" 2 1272.6786 2.47 137342 3455 3 1272.679112 425.2335 U4\U6 small nuclear ribonucleoprotein Prp31 OS=Homo sapiens OX=9606 GN=PRPF31 PE=1 SV=2 8.72 1302.1 - 1.28E+06 - - - 0.3921 - 2.529 0.459 - 367.3 1 2 1 0.0005 11 0 0 0 5.25E+06 2.13E+06 - - - 6.293 1 221125_WJC_METTL3_EV_vs_WT_F10.03457.03457.2 7.47E-06 18/30 Y.GGGGSGGGYGGGSGSR.G "sp|P35527|K1C9_HUMAN,tr|K7EQQ3|K7EQQ3_HUMAN" 2 1225.5072 6.3 137344 3457 2 1225.507524 613.7609 "Keratin, type I cytoskeletal 9 OS=Homo sapiens OX=9606 GN=KRT9 PE=1 SV=3" 8.75 1302.3 - 817839 - - - 0.2717 - 3.492 0.689 - 1081.1 1 1 0 0.0003 16 0 0 0 6.27E+06 9.95E+05 - - - 7.2042 0.9999 221125_WJC_METTL3_EV_vs_WT_F10.03459.03459.2 1.10E-06 18-Oct K.NNQESDC[160.03]VSK.K "sp|A6NDG6|PGP_HUMAN,tr|H3BV17|H3BV17_HUMAN" 2 1179.4826 1.05 137346 3459 2 1179.483287 590.7486 Glycerol-3-phosphate phosphatase OS=Homo sapiens OX=9606 GN=PGP PE=1 SV=1 4.37 1302.6 - 686076 - - - 0.5689 - 2.012 0.623 - 543.8 1 2 0 0.0007 10 0 0 0 2.42E+06 2.30E+06 - - - 5.5937 0.9887 221125_WJC_METTL3_EV_vs_WT_F10.03462.03462.2 1.8 14-Nov K.LK[136.11]EDK[136.11]LEK[136.11].Q "sp|Q8ND56|LS14A_HUMAN,sp|Q07866|KLC1_HUMAN,tr|G3V5R9|G3V5R9_HUMAN,tr|G3V3H3|G3V3H3_HUMAN,tr|G3V2P7|G3V2P7_HUMAN,tr|F8W6L3|F8W6L3_HUMAN,tr|E7EVH7|E7EVH7_HUMAN,tr|A0A140TA76|A0A140TA76_HUMAN,tr|K7EMZ9|K7EMZ9_HUMAN,tr|G3V2E7|G3V2E7_HUMAN,tr|G5E9S8|G5E9S8_HUMAN" 11 1025.6183 1.01 137349 3462 2 1025.61889 513.8164 Protein LSM14 homolog A OS=Homo sapiens OX=9606 GN=LSM14A PE=1 SV=3 6.18 1302.9 - 388221 - - - 0.5645 - 2.066 0.165 - 295.7 1 2 2 0.0006 8 0 0 0 6.35E+07 6.29E+07 - - - 2.4479 0.9046 221125_WJC_METTL3_EV_vs_WT_F10.03464.03464.2 0.0213 18-May R.HAEDDSKIDS.- "sp|Q9H2Y7|ZN106_HUMAN,tr|H3BS99|H3BS99_HUMAN,tr|A0A0C4DGM5|A0A0C4DGM5_HUMAN,tr|H3BSS6|H3BSS6_HUMAN" 4 1115.4731 0.55 137350 3464 2 1115.476768 558.7438 Zinc finger protein 106 OS=Homo sapiens OX=9606 GN=ZNF106 PE=1 SV=1 4.22 1303.2 - 326452 - - - 3.291 - 0.982 0.4 - 51.3 1 2 1 0.0037 10 0 0 0 1.29E+06 2.35E+06 - - - 1.9435 0.995 221125_WJC_METTL3_EV_vs_WT_F10.03468.03468.2 0.223 20-Sep R.VRQTQVNEATK.A "sp|Q8WWY3|PRP31_HUMAN,tr|E7EVX8|E7EVX8_HUMAN" 2 1272.6786 -1 137354 3468 2 1272.678767 637.3466 U4\U6 small nuclear ribonucleoprotein Prp31 OS=Homo sapiens OX=9606 GN=PRPF31 PE=1 SV=2 8.72 1303.7 - 219709 - - - 0.121 - 1.951 0.311 - 191.8 1 2 1 0.0002 11 0 0 0 0.00E+00 0.00E+00 - - - 3.146 1 221125_WJC_METTL3_EV_vs_WT_F10.03469.03469.2 8.01E-07 14/24 R.GESENAGTNQETR[166.11].S sp|Q08170|SRSF4_HUMAN 1 1401.5996 1.74 137355 3469 2 1401.600153 701.8071 Serine\arginine-rich splicing factor 4 OS=Homo sapiens OX=9606 GN=SRSF4 PE=1 SV=2 4.25 1303.8 - 200206 - - - 0.406 - 2.992 0.647 - 658.9 1 2 0 0.0006 13 0 0 0 6.61E+06 3.80E+06 - - - 6.6323 0.9166 221125_WJC_METTL3_EV_vs_WT_F10.03470.03470.2 0.446 14-Nov K.LKEDKLEK.Q "sp|Q8ND56|LS14A_HUMAN,sp|Q07866|KLC1_HUMAN,tr|G3V5R9|G3V5R9_HUMAN,tr|G3V3H3|G3V3H3_HUMAN,tr|G3V2P7|G3V2P7_HUMAN,tr|F8W6L3|F8W6L3_HUMAN,tr|E7EVH7|E7EVH7_HUMAN,tr|A0A140TA76|A0A140TA76_HUMAN,tr|K7EMZ9|K7EMZ9_HUMAN,tr|G3V2E7|G3V2E7_HUMAN,tr|G5E9S8|G5E9S8_HUMAN" 11 1001.5757 1.01 137356 3470 2 1001.579636 501.7951 Protein LSM14 homolog A OS=Homo sapiens OX=9606 GN=LSM14A PE=1 SV=3 6.18 1303.9 - 171751 - - - 3.9188 - 2.083 0.164 - 295.2 1 2 2 0.0039 8 0 0 0 6.35E+07 6.29E+07 - - - 2.4642 1 221125_WJC_METTL3_EV_vs_WT_F10.03471.03471.2 2.93E-07 13/30 R.AAGGGAGSSEDDAQSR[166.11].R "sp|Q9H4A6|GOLP3_HUMAN,tr|D6REM1|D6REM1_HUMAN" 2 1444.6054 -1 137357 3471 2 1444.604523 723.31 Golgi phosphoprotein 3 OS=Homo sapiens OX=9606 GN=GOLPH3 PE=1 SV=1 4.03 1304.1 - 164728 - - - -0.6057 - 2.217 0.7 - 404.7 1 2 0 -0.0009 16 0 0 0 0.00E+00 0.00E+00 - - - 6.1683 1 221125_WJC_METTL3_EV_vs_WT_F10.03473.03473.2 2.26E-10 13/30 R.AAGGGAGSSEDDAQSR.R "sp|Q9H4A6|GOLP3_HUMAN,tr|D6REM1|D6REM1_HUMAN" 2 1434.5971 -1 137358 3473 2 1434.599108 718.3058 Golgi phosphoprotein 3 OS=Homo sapiens OX=9606 GN=GOLPH3 PE=1 SV=1 4.03 1304.3 - 165110 - - - 1.3802 - 2.896 0.68 - 469 1 2 0 0.002 16 0 0 0 0.00E+00 0.00E+00 - - - 6.6771 0.9997 221125_WJC_METTL3_EV_vs_WT_F10.03484.03484.2 4.51E-05 15/20 R.FGGPVHHQAQR.F sp|Q15717|ELAV1_HUMAN 1 1232.6163 2.63 137369 3484 2 1232.613058 617.3154 ELAV-like protein 1 OS=Homo sapiens OX=9606 GN=ELAVL1 PE=1 SV=2 9.76 1305.3 - 574327 - - - -2.6204 - 2.54 0.557 - 624.2 1 2 0 -0.0032 11 0 0 0 2.90E+07 1.11E+07 - - - 5.6757 0.9999 221125_WJC_METTL3_EV_vs_WT_F10.03487.03487.2 1.93E-06 13/20 R.FGGPVHHQAQR[166.11].F sp|Q15717|ELAV1_HUMAN 1 1242.6246 2.62 137372 3487 2 1242.62425 622.3196 ELAV-like protein 1 OS=Homo sapiens OX=9606 GN=ELAVL1 PE=1 SV=2 9.76 1305.6 - 486190 - - - -0.2479 - 2.581 0.471 - 518.4 1 2 0 -0.0003 11 0 0 0 2.89E+07 1.11E+07 - - - 5.0848 0.9502 221125_WJC_METTL3_EV_vs_WT_F10.03492.03492.2 0.0525 14-May R.GEGANHGK[136.11].G tr|G3V349|G3V349_HUMAN 1 776.3657 0.1 137375 3492 2 776.367763 389.1901 Interferon alpha-inducible protein 27-like protein 1 OS=Homo sapiens OX=9606 GN=IFI27L1 PE=4 SV=1 6.75 1306.2 - 5.12E+06 - - - 2.7023 - 0.995 0.186 - 70.7 1 2 0 0.0021 8 0 0 0 9.76E+06 9.34E+07 - - - 0.399 0.9644 221125_WJC_METTL3_EV_vs_WT_F10.03495.03495.2 0.000349 22-Sep K.C[160.03]GGAGHIASDC[160.03]K.F "sp|Q15637|SF01_HUMAN,tr|H7C561|H7C561_HUMAN,tr|A0A7P0T9U7|A0A7P0T9U7_HUMAN" 3 1231.5074 1.77 137378 3495 2 1232.513068 616.761 Splicing factor 1 OS=Homo sapiens OX=9606 GN=SF1 PE=1 SV=4 6.73 1306.4 - 1.50E+06 - - - 816.6228 - 1.387 0.491 - 106.2 1 2 0 1.0057 12 0 0 0 2.15E+07 1.21E+07 - - - 3.2125 0.983 221125_WJC_METTL3_EV_vs_WT_F10.03505.03505.3 0.0153 Oct-36 R.SK[136.11]ETQEELNK[136.11].A sp|Q8TBA6|GOGA5_HUMAN 1 1220.6219 1.58 137386 3505 3 1220.618844 407.8813 Golgin subfamily A member 5 OS=Homo sapiens OX=9606 GN=GOLGA5 PE=1 SV=3 4.78 1307.6 - 1.52E+06 - - - -2.5413 - 1.729 0.263 - 133.5 1 2 1 -0.0031 10 0 0 0 5.11E+07 3.23E+07 - - - 3.0704 1 221125_WJC_METTL3_EV_vs_WT_F10.03506.03506.2 0.000147 16/28 K.KGQGGAGAGDDEEED.- sp|P46781|RS9_HUMAN 1 1433.5543 1.17 137387 3506 2 1433.550634 717.7844 40S ribosomal protein S9 OS=Homo sapiens OX=9606 GN=RPS9 PE=1 SV=3 3.87 1307.7 - 1.09E+06 - - - -2.5294 - 2.702 0.718 - 616.2 1 2 0 -0.0036 15 0 0 0 1.58E+08 1.35E+08 - - - 6.7868 0.9905 221125_WJC_METTL3_EV_vs_WT_F10.03507.03507.2 0.0222 13/18 R.SKETQEELNK.A sp|Q8TBA6|GOGA5_HUMAN 1 1204.5935 1.85 137388 3507 2 1204.58908 603.304 Golgin subfamily A member 5 OS=Homo sapiens OX=9606 GN=GOLGA5 PE=1 SV=3 4.78 1307.8 - 935006 - - - -3.7075 - 2.632 0.438 - 389 1 2 1 -0.0045 10 0 0 0 1.80E+07 9.71E+06 - - - 4.9759 1 221125_WJC_METTL3_EV_vs_WT_F10.03508.03508.2 0.000182 15/28 K.K[136.11]GQGGAGAGDDEEED.- sp|P46781|RS9_HUMAN 1 1441.5685 1.17 137389 3508 2 1441.564484 721.7915 40S ribosomal protein S9 OS=Homo sapiens OX=9606 GN=RPS9 PE=1 SV=3 3.87 1308 - 904427 - - - -2.7581 - 2.656 0.675 - 558 1 2 0 -0.004 15 0 0 0 1.58E+08 1.35E+08 - - - 6.4269 1 221125_WJC_METTL3_EV_vs_WT_F10.03511.03511.2 1.90E-06 16/22 K.C[160.03]GGAGHIASDC[160.03]K[136.11].F "sp|Q15637|SF01_HUMAN,tr|H7C561|H7C561_HUMAN,tr|A0A7P0T9U7|A0A7P0T9U7_HUMAN" 3 1239.5216 1.77 137390 3511 2 1239.518823 620.7681 Splicing factor 1 OS=Homo sapiens OX=9606 GN=SF1 PE=1 SV=4 6.73 1308.4 - 974634 - - - -2.2331 - 3.289 0.689 - 964 1 2 0 -0.0028 12 0 0 0 2.15E+07 1.21E+07 - - - 7.2617 0.9514 221125_WJC_METTL3_EV_vs_WT_F10.03517.03517.3 0.0693 Aug-36 R.SKETQEELNK.A sp|Q8TBA6|GOGA5_HUMAN 1 1204.5935 1.57 137394 3517 3 1204.590275 402.5385 Golgin subfamily A member 5 OS=Homo sapiens OX=9606 GN=GOLGA5 PE=1 SV=3 4.78 1309.1 - 5.35E+06 - - - -2.7154 - 1.537 0.237 - 102.8 1 2 1 -0.0033 10 0 0 0 5.11E+07 3.25E+07 - - - 2.4367 0.995 221125_WJC_METTL3_EV_vs_WT_F10.03520.03520.2 0.00106 18-Dec R.SK[136.11]ETQEELNK[136.11].A sp|Q8TBA6|GOGA5_HUMAN 1 1220.6219 1.85 137396 3520 2 1220.618981 611.3182 Golgin subfamily A member 5 OS=Homo sapiens OX=9606 GN=GOLGA5 PE=1 SV=3 4.78 1309.4 - 1.16E+06 - - - -2.4291 - 1.905 0.493 - 328.4 1 2 1 -0.003 10 0 0 0 1.80E+07 9.71E+06 - - - 4.4803 1 221125_WJC_METTL3_EV_vs_WT_F10.03524.03524.2 3.07E-07 17/26 K.TGSGGVASSSESNR[166.11].D "sp|Q15428|SF3A2_HUMAN,tr|K7EMT0|K7EMT0_HUMAN" 2 1304.5832 0.81 137400 3524 2 1304.579211 653.2989 Splicing factor 3A subunit 2 OS=Homo sapiens OX=9606 GN=SF3A2 PE=1 SV=2 5.66 1309.8 - 861249 - - - -3.0623 - 3.329 0.688 - 734.8 1 2 0 -0.004 14 0 0 0 6.15E+07 7.63E+07 - - - 7.1394 1 221125_WJC_METTL3_EV_vs_WT_F10.03525.03525.2 6.14E-11 16/26 K.TGSGGVASSSESNR.D "sp|Q15428|SF3A2_HUMAN,tr|K7EMT0|K7EMT0_HUMAN" 2 1294.5749 0.81 137401 3525 2 1294.570702 648.2947 Splicing factor 3A subunit 2 OS=Homo sapiens OX=9606 GN=SF3A2 PE=1 SV=2 5.66 1310 - 625279 - - - -3.2706 - 2.892 0.711 - 665.2 1 2 0 -0.0042 14 0 0 0 6.15E+07 7.63E+07 - - - 6.956 0.9999 221125_WJC_METTL3_EV_vs_WT_F10.03532.03532.3 2.62E-05 Dec-44 K.C[160.03]GGAGHIASDC[160.03]K[136.11].F "sp|Q15637|SF01_HUMAN,tr|H7C561|H7C561_HUMAN,tr|A0A7P0T9U7|A0A7P0T9U7_HUMAN" 3 1239.5216 1.13 137406 3532 3 1239.518401 414.1811 Splicing factor 1 OS=Homo sapiens OX=9606 GN=SF1 PE=1 SV=4 6.73 1310.8 - 4.42E+06 - - - -2.5736 - 1.932 0.525 - 144.8 1 2 0 -0.0032 12 0 0 0 6.18E+07 5.46E+07 - - - 6.2178 0.8921 221125_WJC_METTL3_EV_vs_WT_F10.03537.03537.2 0.00076 24-Aug Y.GGSSSSSSYGSGR.R "sp|P09651|ROA1_HUMAN,tr|A0A7I2YQX9|A0A7I2YQX9_HUMAN,tr|A0A7I2YQW0|A0A7I2YQW0_HUMAN,tr|A0A7I2V3J5|A0A7I2V3J5_HUMAN,tr|A0A7I2V3R8|A0A7I2V3R8_HUMAN,tr|A0A7I2YQR6|A0A7I2YQR6_HUMAN,tr|F8W6I7|F8W6I7_HUMAN,tr|A0A7I2YQY2|A0A7I2YQY2_HUMAN,tr|H0YH80|H0YH80_HUMAN,tr|A0A7I2V3S1|A0A7I2V3S1_HUMAN,tr|A0A7I2V3W0|A0A7I2V3W0_HUMAN,tr|A0A2R8Y4L2|A0A2R8Y4L2_HUMAN" 12 1174.4851 1.64 137411 3537 2 1174.480899 588.2498 Heterogeneous nuclear ribonucleoprotein A1 OS=Homo sapiens OX=9606 GN=HNRNPA1 PE=1 SV=5 8.75 1311.4 - 218185 - - - -3.5411 - 1.502 0.472 - 138.6 1 1 0 -0.0042 13 0 0 0 2.26E+06 1.38E+06 - - - 3.5699 0.9959 221125_WJC_METTL3_EV_vs_WT_F10.03548.03548.2 3.61E-05 14/20 R.AKEAAEQDVEK.K "sp|P26373|RL13_HUMAN,tr|J3KS98|J3KS98_HUMAN" 2 1216.5935 0.59 137419 3548 2 1216.590282 609.304 60S ribosomal protein L13 OS=Homo sapiens OX=9606 GN=RPL13 PE=1 SV=4 4.41 1312.6 - 1.18E+06 - - - -2.6829 - 2.313 0.522 - 446.1 1 2 1 -0.0033 11 0 0 0 1.47E+07 2.50E+07 - - - 5.1639 0.9931 221125_WJC_METTL3_EV_vs_WT_F10.03555.03555.3 0.00933 Sep-48 R.LVEGESDNRNQQK.M sp|O94776|MTA2_HUMAN 1 1515.7277 1.17 137423 3555 3 1515.726395 506.2499 Metastasis-associated protein MTA2 OS=Homo sapiens OX=9606 GN=MTA2 PE=1 SV=1 4.68 1313.3 - 1.41E+06 - - - -0.8926 - 1.639 0.282 - 62.9 1 2 1 -0.0014 13 0 0 0 2.28E+07 1.95E+07 - - - 3.0233 0.9993 221125_WJC_METTL3_EV_vs_WT_F10.03562.03562.3 0.0132 Dec-40 R.AKEAAEQDVEK.K "sp|P26373|RL13_HUMAN,tr|J3KS98|J3KS98_HUMAN" 2 1216.5935 0.26 137428 3562 3 1216.591921 406.5385 60S ribosomal protein L13 OS=Homo sapiens OX=9606 GN=RPL13 PE=1 SV=4 4.41 1314.2 - 2.46E+06 - - - -1.3357 - 2.313 0.361 - 275.2 1 2 1 -0.0016 11 0 0 0 6.73E+07 2.54E+08 - - - 4.9465 0.9828 221125_WJC_METTL3_EV_vs_WT_F10.03576.03576.2 2.45 14-Jun R.REPLPSRR.D "sp|Q96E39|RMXL1_HUMAN,sp|P38159|RBMX_HUMAN,tr|H3BUY5|H3BUY5_HUMAN,tr|H3BT71|H3BT71_HUMAN,tr|H0Y6E7|H0Y6E7_HUMAN" 5 1009.5781 0.69 137438 3576 2 1009.578436 505.7963 "RNA binding motif protein, X-linked-like-1 OS=Homo sapiens OX=9606 GN=RBMXL1 PE=1 SV=1" 11.7 1316 - 391645 - - - 0.3219 - 1.233 0.083 - 117.8 1 2 0 0.0003 8 0 0 0 9.44E+06 1.37E+07 - - - 0.2856 0.9428 221125_WJC_METTL3_EV_vs_WT_F10.03582.03582.3 0.0039 Dec-32 L.AEK[136.11]DEFEHK[136.11].R "sp|P0DMV8|HS71A_HUMAN,sp|P0DMV9|HS71B_HUMAN,tr|V9GZ37|V9GZ37_HUMAN,tr|A0A0G2JIW1|A0A0G2JIW1_HUMAN" 4 1147.5481 0.001 137442 3582 3 1147.547123 383.5233 Heat shock 70 kDa protein 1A OS=Homo sapiens OX=9606 GN=HSPA1A PE=1 SV=1 4.83 1316.8 - 2.33E+06 - - - -0.8104 - 2.093 0.378 - 175.3 1 1 1 -0.0009 9 0 0 0 0.00E+00 4.33E+07 - - - 4.9801 0.9998 221125_WJC_METTL3_EV_vs_WT_F10.03584.03584.3 0.0199 Dec-44 K.IDASK[136.11]NEEDEGK[136.11].M tr|D6RBQ9|D6RBQ9_HUMAN 1 1349.6282 1.51 137444 3584 3 1349.628519 450.8833 Heterogeneous nuclear ribonucleoprotein D0 (Fragment) OS=Homo sapiens OX=9606 GN=HNRNPD PE=1 SV=1 4.18 1317 - 936553 - - - 0.2704 - 2.566 0.449 - 181.8 1 2 1 0.0004 12 0 0 0 8.61E+07 5.71E+07 - - - 6.1579 0.997 221125_WJC_METTL3_EV_vs_WT_F10.03588.03588.2 3.49E-06 22-Nov K.IDASK[136.11]NEEDEGK[136.11].M tr|D6RBQ9|D6RBQ9_HUMAN 1 1349.6282 1.52 137448 3588 2 1349.631227 675.8214 Heterogeneous nuclear ribonucleoprotein D0 (Fragment) OS=Homo sapiens OX=9606 GN=HNRNPD PE=1 SV=1 4.18 1317.5 - 78838.7 - - - 2.2769 - 2.258 0.556 - 443.5 1 2 1 0.0031 12 0 0 0 7.89E+06 5.19E+06 - - - 5.2897 0.9999 221125_WJC_METTL3_EV_vs_WT_F10.03591.03591.3 6.68E-05 Oct-36 R.DDETDEPKPK.R "sp|Q8IX12|CCAR1_HUMAN,tr|F5H1H2|F5H1H2_HUMAN,tr|A0A0C4DGG8|A0A0C4DGG8_HUMAN" 3 1172.5197 5.73 137449 3591 3 1172.519005 391.8472 Cell division cycle and apoptosis regulator protein 1 OS=Homo sapiens OX=9606 GN=CCAR1 PE=1 SV=2 4.11 1317.9 - 1.65E+06 - - - -0.6038 - 1.85 0.441 - 179.7 1 2 0 -0.0007 10 0 0 0 3.97E+07 6.93E+06 - - - 5.2531 0.9421 221125_WJC_METTL3_EV_vs_WT_F10.03593.03593.3 0.0494 Sep-40 L.ADATEQVGQHK.D "sp|Q9BZZ5|API5_HUMAN,tr|E9PQK6|E9PQK6_HUMAN,tr|G3V1C3|G3V1C3_HUMAN" 3 1182.5629 1.19 137451 3593 3 1182.562705 395.1949 Apoptosis inhibitor 5 OS=Homo sapiens OX=9606 GN=API5 PE=1 SV=3 5.32 1318.1 - 625244 - - - -0.1776 - 1.635 0.338 - 100.5 1 1 0 -0.0002 11 0 0 0 1.46E+07 1.23E+07 - - - 3.705 0.9997 221125_WJC_METTL3_EV_vs_WT_F10.03597.03597.2 6.72E-07 18-Sep R.DDETDEPKPK.R "sp|Q8IX12|CCAR1_HUMAN,tr|F5H1H2|F5H1H2_HUMAN,tr|A0A0C4DGG8|A0A0C4DGG8_HUMAN" 3 1172.5197 18.24 137455 3597 2 1172.51863 587.2671 Cell division cycle and apoptosis regulator protein 1 OS=Homo sapiens OX=9606 GN=CCAR1 PE=1 SV=2 4.11 1318.6 - 246994 - - - -0.9237 - 2.001 0.402 - 372.3 1 2 0 -0.0011 10 0 0 0 6.08E+06 3.33E+05 - - - 3.946 0.9999 221125_WJC_METTL3_EV_vs_WT_F10.03602.03602.3 4.32E-05 Nov-44 K.EVNGHEVGNNPK.E "sp|Q9NZW5|PALS2_HUMAN,tr|C9J4Q3|C9J4Q3_HUMAN,tr|B8ZZG1|B8ZZG1_HUMAN,tr|C9JGI8|C9JGI8_HUMAN" 4 1292.6109 1.91 137458 3602 3 1292.610332 431.8776 Protein PALS2 OS=Homo sapiens OX=9606 GN=PALS2 PE=1 SV=2 5.4 1319.2 - 1.79E+06 - - - -0.4611 - 1.958 0.492 - 139.1 1 2 0 -0.0006 12 0 0 0 4.45E+07 2.32E+07 - - - 5.8876 0.999 221125_WJC_METTL3_EV_vs_WT_F10.03603.03603.2 0.000141 13/22 K.IDASKNEEDEGK.M tr|D6RBQ9|D6RBQ9_HUMAN 1 1333.5998 1.52 137459 3603 2 1333.598764 667.8072 Heterogeneous nuclear ribonucleoprotein D0 (Fragment) OS=Homo sapiens OX=9606 GN=HNRNPD PE=1 SV=1 4.18 1319.3 - 619929 - - - -0.7424 - 2.657 0.545 - 697.2 1 2 1 -0.001 12 0 0 0 7.89E+06 5.19E+06 - - - 5.6372 0.9954 221125_WJC_METTL3_EV_vs_WT_F10.03604.03604.3 0.0115 13/40 K.QATENAKEEVR.R sp|P26641|EF1G_HUMAN 1 1273.6262 1.04 137460 3604 3 1273.63261 425.5494 Elongation factor 1-gamma OS=Homo sapiens OX=9606 GN=EEF1G PE=1 SV=3 4.79 1319.4 - 868732 - - - 4.9991 - 2.456 0.412 - 297.8 1 2 1 0.0064 11 0 0 0 8.45E+06 8.12E+06 - - - 5.6842 0.9998 221125_WJC_METTL3_EV_vs_WT_F10.03606.03606.2 0.000733 16-Jul R.DGQHYGDDR.H sp|Q14151|SAFB2_HUMAN 1 1061.4162 1.49 137462 3606 2 1061.416185 531.7154 Scaffold attachment factor B2 OS=Homo sapiens OX=9606 GN=SAFB2 PE=1 SV=1 4.41 1319.6 - 381799 - - - -0.0612 - 1.39 0.574 - 147.2 1 2 0 -0.0001 9 0 0 0 3.30E+06 2.21E+06 - - - 4.2332 0.9988 221125_WJC_METTL3_EV_vs_WT_F10.03607.03607.3 0.0125 Dec-36 R.QRQQQQEALR.R "sp|Q6Y7W6|GGYF2_HUMAN,tr|A0A7I2V3H7|A0A7I2V3H7_HUMAN,tr|I1E4Y6|I1E4Y6_HUMAN,tr|A0A7I2V516|A0A7I2V516_HUMAN,tr|A0A7I2V3H0|A0A7I2V3H0_HUMAN,tr|A0A7I2V361|A0A7I2V361_HUMAN" 6 1283.6694 2.44 137463 3607 3 1283.670053 428.8971 GRB10-interacting GYF protein 2 OS=Homo sapiens OX=9606 GN=GIGYF2 PE=1 SV=1 9.6 1319.8 - 320293 - - - 0.4736 - 1.986 0.341 - 274.1 1 2 1 0.0006 10 0 0 0 3.15E+06 1.29E+06 - - - 4.3454 0.9094 221125_WJC_METTL3_EV_vs_WT_F10.03608.03608.2 0.00816 20-Dec L.DASKNEEDEGK.M tr|D6RBQ9|D6RBQ9_HUMAN 1 1220.5157 0.09 137464 3608 2 1220.514944 611.2651 Heterogeneous nuclear ribonucleoprotein D0 (Fragment) OS=Homo sapiens OX=9606 GN=HNRNPD PE=1 SV=1 4.18 1319.9 - 288287 - - - -0.6112 - 2.2 0.464 - 419.6 1 1 1 -0.0007 11 0 0 0 3.49E+06 3.74E+07 - - - 4.6008 0.7919 221125_WJC_METTL3_EV_vs_WT_F10.03609.03609.2 0.00094 16-Aug L.AEK[136.11]DEFEHK[136.11].R "sp|P0DMV8|HS71A_HUMAN,sp|P0DMV9|HS71B_HUMAN,tr|V9GZ37|V9GZ37_HUMAN,tr|A0A0G2JIW1|A0A0G2JIW1_HUMAN" 4 1147.5481 0.03 137465 3609 2 1147.548 574.7813 Heat shock 70 kDa protein 1A OS=Homo sapiens OX=9606 GN=HSPA1A PE=1 SV=1 4.83 1320 - 283755 - - - -0.0462 - 1.461 0.425 - 192.9 1 1 1 -0.0001 9 0 0 0 8.16E+04 2.47E+06 - - - 3.2769 0.9327 221125_WJC_METTL3_EV_vs_WT_F10.03610.03610.2 9.05E-07 20-Oct L.DASK[136.11]NEEDEGK[136.11].M tr|D6RBQ9|D6RBQ9_HUMAN 1 1236.5441 0.09 137466 3610 2 1236.54287 619.2793 Heterogeneous nuclear ribonucleoprotein D0 (Fragment) OS=Homo sapiens OX=9606 GN=HNRNPD PE=1 SV=1 4.18 1320.2 - 229636 - - - -0.9866 - 2.293 0.566 - 248.2 1 1 1 -0.0012 11 0 0 0 3.49E+06 4.00E+07 - - - 5.4661 0.999 221125_WJC_METTL3_EV_vs_WT_F10.03611.03611.2 1.20E-05 22-Aug K.EVNGHEVGNNPK.E "sp|Q9NZW5|PALS2_HUMAN,tr|C9J4Q3|C9J4Q3_HUMAN,tr|B8ZZG1|B8ZZG1_HUMAN,tr|C9JGI8|C9JGI8_HUMAN" 4 1292.6109 2.64 137467 3611 2 1292.606061 647.3127 Protein PALS2 OS=Homo sapiens OX=9606 GN=PALS2 PE=1 SV=2 5.4 1320.3 - 137675 - - - -3.7652 - 1.999 0.538 - 173.6 1 2 0 -0.0049 12 0 0 0 2.58E+06 9.76E+05 - - - 4.8356 0.9996 221125_WJC_METTL3_EV_vs_WT_F10.03621.03621.2 0.00599 18-Jul R.VHDPVTAK[136.11]PK[136.11].L "sp|P13995|MTDC_HUMAN,tr|A0A7I2V482|A0A7I2V482_HUMAN,tr|A0A7I2V2U6|A0A7I2V2U6_HUMAN,tr|A0A7I2YQD4|A0A7I2YQD4_HUMAN,tr|B9A062|B9A062_HUMAN" 5 1106.6419 1.09 137475 3621 2 1106.641288 554.3282 "Bifunctional methylenetetrahydrofolate dehydrogenase\cyclohydrolase, mitochondrial OS=Homo sapiens OX=9606 GN=MTHFD2 PE=1 SV=2" 8.57 1321.4 - 274811 - - - -0.5476 - 1.33 0.458 - 174 1 2 0 -0.0006 10 0 0 0 6.89E+06 6.33E+06 - - - 3.2196 0.9991 221125_WJC_METTL3_EV_vs_WT_F10.03623.03623.2 0.000346 22-May K.EVNGHEVGNNPK[136.11].E "sp|Q9NZW5|PALS2_HUMAN,tr|C9J4Q3|C9J4Q3_HUMAN,tr|B8ZZG1|B8ZZG1_HUMAN,tr|C9JGI8|C9JGI8_HUMAN" 4 1300.6251 2.64 137477 3623 2 1300.622736 651.3198 Protein PALS2 OS=Homo sapiens OX=9606 GN=PALS2 PE=1 SV=2 5.4 1321.7 - 116999 - - - -1.8391 - 1.338 0.452 - 70.7 1 2 0 -0.0024 12 0 0 0 2.58E+06 9.76E+05 - - - 3.1449 0.9976 221125_WJC_METTL3_EV_vs_WT_F10.03624.03624.2 0.00109 18-May R.DDETDEPK[136.11]PK[136.11].R "sp|Q8IX12|CCAR1_HUMAN,tr|F5H1H2|F5H1H2_HUMAN,tr|A0A0C4DGG8|A0A0C4DGG8_HUMAN" 3 1188.5481 18.24 137478 3624 2 1188.544514 595.2813 Cell division cycle and apoptosis regulator protein 1 OS=Homo sapiens OX=9606 GN=CCAR1 PE=1 SV=2 4.11 1321.8 - 71674 - - - -3.0281 - 1.161 0.476 - 93.1 1 2 0 -0.0036 10 0 0 0 6.08E+06 3.33E+05 - - - 2.9723 0.8484 221125_WJC_METTL3_EV_vs_WT_F10.03646.03646.2 1.42 16-Jun R.DQEEEYKSK.Y sp|Q8N1N4|K2C78_HUMAN 1 1154.5091 12.87 137496 3646 2 1154.507083 578.2619 "Keratin, type II cytoskeletal 78 OS=Homo sapiens OX=9606 GN=KRT78 PE=1 SV=2" 4.41 1324.5 - 83505.7 - - - -1.7886 - 1.184 0.163 - 95.1 1 2 1 -0.0021 9 0 0 0 1.10E+06 8.57E+04 - - - 0.7329 0.9999 221125_WJC_METTL3_EV_vs_WT_F10.03651.03651.3 0.00474 Nov-44 K.GSGSPTHSLSQK[136.11].S "sp|Q9BSJ6|PIMRE_HUMAN,tr|I3L156|I3L156_HUMAN,tr|I3L419|I3L419_HUMAN,tr|I3L2R2|I3L2R2_HUMAN" 4 1192.5928 1.27 137499 3651 3 1192.594005 398.5382 Protein PIMREG OS=Homo sapiens OX=9606 GN=PIMREG PE=1 SV=1 8.76 1325.1 - 674566 - - - 1.0398 - 1.941 0.417 - 155.9 1 2 0 0.0012 12 0 0 0 1.06E+07 8.40E+06 - - - 5.0271 1 221125_WJC_METTL3_EV_vs_WT_F10.03653.03653.3 6.99E-05 13/48 R.LENNDNKPVTNSR.D "sp|Q9BYJ9|YTHD1_HUMAN,sp|Q7Z739|YTHD3_HUMAN,tr|A0A087X0Q1|A0A087X0Q1_HUMAN,tr|A0A024R7W5|A0A024R7W5_HUMAN,tr|A0A087WY31|A0A087WY31_HUMAN" 5 1499.7328 1.64 137501 3653 3 1499.732506 500.9182 YTH domain-containing family protein 1 OS=Homo sapiens OX=9606 GN=YTHDF1 PE=1 SV=1 6.07 1325.3 - 469591 - - - -0.2187 - 2.476 0.519 - 199.6 1 2 0 -0.0003 13 0 0 0 3.87E+08 2.36E+08 - - - 6.7844 0.9997 221125_WJC_METTL3_EV_vs_WT_F10.03654.03654.2 0.000345 22-Jul K.GSGSPTHSLSQK[136.11].S "sp|Q9BSJ6|PIMRE_HUMAN,tr|I3L156|I3L156_HUMAN,tr|I3L419|I3L419_HUMAN,tr|I3L2R2|I3L2R2_HUMAN" 4 1192.5928 1.38 137502 3654 2 1192.591613 597.3037 Protein PIMREG OS=Homo sapiens OX=9606 GN=PIMREG PE=1 SV=1 8.76 1325.4 - 87515 - - - -0.966 - 1.655 0.471 - 137.1 1 2 0 -0.0012 12 0 0 0 1.96E+06 1.42E+06 - - - 3.845 0.9999 221125_WJC_METTL3_EV_vs_WT_F10.03657.03657.3 0.000385 Oct-36 K.IGK[136.11]PHTVPC[160.03]K[136.11].V "sp|P15880|RS2_HUMAN,tr|I3L404|I3L404_HUMAN,tr|E9PM36|E9PM36_HUMAN,tr|E9PPT0|E9PPT0_HUMAN,tr|E9PMM9|E9PMM9_HUMAN,tr|H0YEN5|H0YEN5_HUMAN" 6 1151.6456 0.05 137503 3657 3 1151.644821 384.8891 40S ribosomal protein S2 OS=Homo sapiens OX=9606 GN=RPS2 PE=1 SV=2 9.31 1325.9 - 1.60E+06 - - - -0.6756 - 2.178 0.412 - 112.1 1 2 0 -0.0008 10 0 0 0 7.51E+06 1.57E+08 - - - 5.4065 1 221125_WJC_METTL3_EV_vs_WT_F10.03658.03658.3 2.79E-07 13/48 K.HNGPNDASDGTVR[166.11].L sp|P31942|HNRH3_HUMAN 1 1348.5995 2.49 137504 3658 3 1348.598561 450.5405 Heterogeneous nuclear ribonucleoprotein H3 OS=Homo sapiens OX=9606 GN=HNRNPH3 PE=1 SV=2 5.21 1326 - 1.11E+06 - - - -0.7148 - 2.821 0.604 - 311.8 1 2 0 -0.001 13 0 0 0 5.00E+07 2.01E+07 - - - 8.0856 1 221125_WJC_METTL3_EV_vs_WT_F10.03665.03665.3 2.65E-05 Nov-48 K.HNGPNDASDGTVR.L sp|P31942|HNRH3_HUMAN 1 1338.5913 2.5 137509 3665 3 1338.58953 447.2044 Heterogeneous nuclear ribonucleoprotein H3 OS=Homo sapiens OX=9606 GN=HNRNPH3 PE=1 SV=2 5.21 1326.8 - 3.99E+06 - - - -1.2887 - 2.376 0.49 - 228.1 1 2 0 -0.0017 13 0 0 0 4.92E+07 1.97E+07 - - - 6.3489 1 221125_WJC_METTL3_EV_vs_WT_F10.03670.03670.2 0.000541 15/24 R.LENNDNKPVTNSR.D "sp|Q9BYJ9|YTHD1_HUMAN,sp|Q7Z739|YTHD3_HUMAN,tr|A0A087X0Q1|A0A087X0Q1_HUMAN,tr|A0A024R7W5|A0A024R7W5_HUMAN,tr|A0A087WY31|A0A087WY31_HUMAN" 5 1499.7328 1.54 137514 3670 2 1499.732898 750.8737 YTH domain-containing family protein 1 OS=Homo sapiens OX=9606 GN=YTHDF1 PE=1 SV=1 6.07 1327.3 - 354844 - - - 0.0427 - 3.067 0.555 - 524.2 1 2 0 0.0001 13 0 0 0 2.02E+07 1.32E+07 - - - 6.0165 1 221125_WJC_METTL3_EV_vs_WT_F10.03673.03673.2 0.00109 13/24 R.LENNDNK[136.11]PVTNSR[166.11].D "sp|Q9BYJ9|YTHD1_HUMAN,sp|Q7Z739|YTHD3_HUMAN,tr|A0A087X0Q1|A0A087X0Q1_HUMAN,tr|A0A024R7W5|A0A024R7W5_HUMAN,tr|A0A087WY31|A0A087WY31_HUMAN" 5 1517.7553 1.54 137517 3673 2 1517.755627 759.8849 YTH domain-containing family protein 1 OS=Homo sapiens OX=9606 GN=YTHDF1 PE=1 SV=1 6.07 1327.7 - 232030 - - - 0.2128 - 2.949 0.561 - 358.6 1 2 0 0.0003 13 0 0 0 2.02E+07 1.32E+07 - - - 5.9601 0.946 221125_WJC_METTL3_EV_vs_WT_F10.03674.03674.2 0.000819 16-Aug L.GKPHTVPC[160.03]K.V "sp|P15880|RS2_HUMAN,tr|I3L404|I3L404_HUMAN,tr|E9PM36|E9PM36_HUMAN,tr|E9PMM9|E9PMM9_HUMAN,tr|H0YEN5|H0YEN5_HUMAN" 5 1022.5331 1.09 137518 3674 2 1022.535647 512.2738 40S ribosomal protein S2 OS=Homo sapiens OX=9606 GN=RPS2 PE=1 SV=2 9.31 1327.8 - 177812 - - - 2.4566 - 1.661 0.414 - 223.3 1 1 0 0.0025 9 0 0 0 9.57E+06 8.77E+06 - - - 3.566 0.9807 221125_WJC_METTL3_EV_vs_WT_F10.03675.03675.2 0.182 18-Jun K.IGK[136.11]PHTVPC[160.03]K[136.11].V "sp|P15880|RS2_HUMAN,tr|I3L404|I3L404_HUMAN,tr|E9PM36|E9PM36_HUMAN,tr|E9PPT0|E9PPT0_HUMAN,tr|E9PMM9|E9PMM9_HUMAN,tr|H0YEN5|H0YEN5_HUMAN" 6 1151.6456 0.9 137519 3675 2 1151.64124 576.8301 40S ribosomal protein S2 OS=Homo sapiens OX=9606 GN=RPS2 PE=1 SV=2 9.31 1328 - 119230 - - - -3.785 - 1.25 0.266 - 56.6 1 2 0 -0.0044 10 0 0 0 6.80E+06 7.57E+06 - - - 1.6272 0.996 221125_WJC_METTL3_EV_vs_WT_F10.03676.03676.2 0.0148 18-Jun R.SHPSDESGYR[166.11].W "tr|B7Z8L1|B7Z8L1_HUMAN,tr|F8VP48|F8VP48_HUMAN,tr|F8WF16|F8WF16_HUMAN" 3 1143.482 1.72 137520 3676 2 1143.479151 572.7483 Periphilin-1 OS=Homo sapiens OX=9606 GN=PPHLN1 PE=1 SV=1 5.3 1328.1 - 94099.7 - - - -2.5221 - 1.157 0.368 - 106.3 1 2 0 -0.0029 10 0 0 0 3.86E+06 2.24E+06 - - - 2.1652 1 221125_WJC_METTL3_EV_vs_WT_F10.03683.03683.3 3.27E-07 14/44 K.R[166.11]EPAEQPGDGER[166.11].T "sp|Q14151|SAFB2_HUMAN,sp|Q15424|SAFB1_HUMAN" 2 1359.6282 1.72 137525 3683 3 1359.626978 454.2167 Scaffold attachment factor B2 OS=Homo sapiens OX=9606 GN=SAFB2 PE=1 SV=1 4.41 1328.7 - 1.04E+06 - - - -0.8958 - 2.647 0.591 - 460 1 2 0 -0.0012 12 0 0 0 1.46E+07 8.52E+06 - - - 7.8269 0.9998 221125_WJC_METTL3_EV_vs_WT_F10.03685.03685.2 0.00689 20-Dec R.QQEQQQQQVAR.E "sp|O00461|GOLI4_HUMAN,tr|F8W785|F8W785_HUMAN" 2 1369.6698 1.3 137527 3685 2 1369.667335 685.8422 Golgi integral membrane protein 4 OS=Homo sapiens OX=9606 GN=GOLIM4 PE=1 SV=1 6 1329 - 781367 - - - -1.8282 - 2.682 0.422 - 673.4 1 2 0 -0.0025 11 0 0 0 4.34E+07 3.33E+07 - - - 4.826 0.9998 221125_WJC_METTL3_EV_vs_WT_F10.03690.03690.2 7.27E-07 14/20 R.QQEQQQQQVAR[166.11].E "sp|O00461|GOLI4_HUMAN,tr|F8W785|F8W785_HUMAN" 2 1379.6781 1.3 137531 3690 2 1379.676288 690.8463 Golgi integral membrane protein 4 OS=Homo sapiens OX=9606 GN=GOLIM4 PE=1 SV=1 6 1329.6 - 569450 - - - -1.3199 - 2.617 0.448 - 1054.1 1 2 0 -0.0018 11 0 0 0 4.34E+07 3.33E+07 - - - 4.9519 1 221125_WJC_METTL3_EV_vs_WT_F10.03692.03692.2 3.34E-07 14/22 L.ENNDNKPVTNSR.D "sp|Q9BYJ9|YTHD1_HUMAN,sp|Q7Z739|YTHD3_HUMAN,tr|A0A087X0Q1|A0A087X0Q1_HUMAN,tr|A0A024R7W5|A0A024R7W5_HUMAN,tr|A0A087WY31|A0A087WY31_HUMAN" 5 1386.6488 2.39 137533 3692 2 1386.643825 694.3317 YTH domain-containing family protein 1 OS=Homo sapiens OX=9606 GN=YTHDF1 PE=1 SV=1 6.17 1329.8 - 368941 - - - -3.5662 - 2.497 0.588 - 475.6 1 1 0 -0.0049 12 0 0 0 3.06E+06 1.28E+06 - - - 5.7902 0.9951 221125_WJC_METTL3_EV_vs_WT_F10.03693.03693.2 2.29E-08 20-Oct E.NNDNK[136.11]PVTNSR[166.11].D "sp|Q9BYJ9|YTHD1_HUMAN,sp|Q7Z739|YTHD3_HUMAN,tr|A0A087X0Q1|A0A087X0Q1_HUMAN,tr|A0A024R7W5|A0A024R7W5_HUMAN,tr|A0A087WY31|A0A087WY31_HUMAN" 5 1275.6286 0.93 137534 3693 2 1275.628302 638.8216 YTH domain-containing family protein 1 OS=Homo sapiens OX=9606 GN=YTHDF1 PE=1 SV=1 8.75 1330 - 229998 - - - -0.2705 - 2.253 0.601 - 250.3 1 1 0 -0.0003 11 0 0 0 3.17E+06 3.42E+06 - - - 5.6772 0.9651 221125_WJC_METTL3_EV_vs_WT_F10.03694.03694.2 3.44E-07 20-Oct E.NNDNKPVTNSR.D "sp|Q9BYJ9|YTHD1_HUMAN,sp|Q7Z739|YTHD3_HUMAN,tr|A0A087X0Q1|A0A087X0Q1_HUMAN,tr|A0A024R7W5|A0A024R7W5_HUMAN,tr|A0A087WY31|A0A087WY31_HUMAN" 5 1257.6062 0.93 137535 3694 2 1257.601801 629.8104 YTH domain-containing family protein 1 OS=Homo sapiens OX=9606 GN=YTHDF1 PE=1 SV=1 8.75 1330.1 - 218201 - - - -3.4796 - 2.128 0.577 - 236.8 1 1 0 -0.0044 11 0 0 0 3.17E+06 3.42E+06 - - - 5.3443 0.7924 221125_WJC_METTL3_EV_vs_WT_F10.03700.03700.3 5.86E-06 15/36 K.IGKPHTVPC[160.03]K.V "sp|P15880|RS2_HUMAN,tr|I3L404|I3L404_HUMAN,tr|E9PM36|E9PM36_HUMAN,tr|E9PPT0|E9PPT0_HUMAN,tr|E9PMM9|E9PMM9_HUMAN,tr|H0YEN5|H0YEN5_HUMAN" 6 1135.6172 0.05 137540 3700 3 1137.618772 379.5463 40S ribosomal protein S2 OS=Homo sapiens OX=9606 GN=RPS2 PE=1 SV=2 9.31 1330.6 - 1.90E+06 - - - 1762.542 - 2.658 0.535 - 245.1 1 2 0 2.0016 10 0 0 0 7.45E+06 1.57E+08 - - - 6.8052 0.9988 221125_WJC_METTL3_EV_vs_WT_F10.03701.03701.3 0.0128 13/40 R.QQEQQQQQVAR.E "sp|O00461|GOLI4_HUMAN,tr|F8W785|F8W785_HUMAN" 2 1369.6698 2.67 137541 3701 3 1369.668104 457.5639 Golgi integral membrane protein 4 OS=Homo sapiens OX=9606 GN=GOLIM4 PE=1 SV=1 6 1330.7 - 763428 - - - -1.2667 - 2.078 0.236 - 401.1 1 2 0 -0.0017 11 0 0 0 1.64E+07 6.14E+06 - - - 3.2485 0.9999 221125_WJC_METTL3_EV_vs_WT_F10.03702.03702.3 7.74E-06 15/48 R.LENNDNKPVTNSR[166.11].D "sp|Q9BYJ9|YTHD1_HUMAN,sp|Q7Z739|YTHD3_HUMAN,tr|A0A087X0Q1|A0A087X0Q1_HUMAN,tr|A0A024R7W5|A0A024R7W5_HUMAN,tr|A0A087WY31|A0A087WY31_HUMAN" 5 1509.7411 - 137542 3702 3 1509.739168 504.2543 YTH domain-containing family protein 1 OS=Homo sapiens OX=9606 GN=YTHDF1 PE=1 SV=1 6.07 1330.9 - 715394 - - - -1.2823 - 2.568 0.429 - 248.9 1 2 0 -0.0019 13 0 0 0 - - - - - 5.8795 0.9992 221125_WJC_METTL3_EV_vs_WT_F10.03705.03705.2 0.00165 24-Aug K.HNGPNDASDGTVR[166.11].L sp|P31942|HNRH3_HUMAN 1 1348.5995 3.06 137545 3705 2 1348.596885 675.307 Heterogeneous nuclear ribonucleoprotein H3 OS=Homo sapiens OX=9606 GN=HNRNPH3 PE=1 SV=2 5.21 1331.1 - 236454 - - - -1.9576 - 1.53 0.423 - 100.4 1 2 0 -0.0026 13 0 0 0 7.95E+06 2.59E+06 - - - 3.2559 0.9915 221125_WJC_METTL3_EV_vs_WT_F10.03708.03708.3 0.144 Oct-36 K.LK[136.11]EIDSK[136.11]EEK[136.11].Y "sp|Q14739|LBR_HUMAN,tr|A0A494C1L1|A0A494C1L1_HUMAN,tr|C9JXK0|C9JXK0_HUMAN" 3 1241.6929 0.69 137546 3708 3 1241.689616 414.9049 Delta(14)-sterol reductase LBR OS=Homo sapiens OX=9606 GN=LBR PE=1 SV=2 4.87 1331.5 - 2.24E+06 - - - -2.6714 - 2.183 0.253 - 67.8 1 2 2 -0.0033 10 0 0 0 1.10E+07 1.59E+07 - - - 3.6398 0.9996 221125_WJC_METTL3_EV_vs_WT_F10.03712.03712.3 0.00206 13/44 K.AALGDSK[136.11]EDTQK[136.11].A "sp|Q9NRA8|4ET_HUMAN,tr|B1AKL4|B1AKL4_HUMAN" 2 1277.6434 1.06 137550 3712 3 1277.640646 426.8884 Eukaryotic translation initiation factor 4E transporter OS=Homo sapiens OX=9606 GN=EIF4ENIF1 PE=1 SV=2 4.56 1331.9 - 1.26E+06 - - - -2.1634 - 2.592 0.436 - 268.5 1 2 1 -0.0028 12 0 0 0 9.13E+06 8.65E+06 - - - 6.0402 0.994 221125_WJC_METTL3_EV_vs_WT_F10.03714.03714.2 0.203 16-Sep K.HSLSGRPLK.V "sp|P52272|HNRPM_HUMAN,tr|M0R019|M0R019_HUMAN,tr|M0R0N3|M0R0N3_HUMAN,tr|A0A087X0X3|A0A087X0X3_HUMAN,tr|M0QYQ7|M0QYQ7_HUMAN,tr|M0R2T0|M0R2T0_HUMAN" 6 993.572 1.82 137552 3714 2 993.568994 497.7933 Heterogeneous nuclear ribonucleoprotein M OS=Homo sapiens OX=9606 GN=HNRNPM PE=1 SV=3 11 1332.1 - 705440 - - - -2.9882 - 1.579 0.237 - 166.2 1 2 0 -0.003 9 0 0 0 8.48E+06 4.65E+06 - - - 2.1121 0.9985 221125_WJC_METTL3_EV_vs_WT_F10.03719.03719.3 3.28E-05 14/40 R.QQEQQQQQVAR[166.11].E "sp|O00461|GOLI4_HUMAN,tr|F8W785|F8W785_HUMAN" 2 1379.6781 2.65 137555 3719 3 1379.675175 460.9 Golgi integral membrane protein 4 OS=Homo sapiens OX=9606 GN=GOLIM4 PE=1 SV=1 6 1332.7 - 992706 - - - -2.1266 - 2.103 0.255 - 435.4 1 2 0 -0.0029 11 0 0 0 1.62E+07 6.14E+06 - - - 3.494 1 221125_WJC_METTL3_EV_vs_WT_F10.03721.03721.2 2.80E-05 16/26 R.GSGGGSSGGSIGGR.G sp|P04264|K2C1_HUMAN 1 1091.4956 67.66 137557 3721 2 1091.492899 546.7551 "Keratin, type II cytoskeletal 1 OS=Homo sapiens OX=9606 GN=KRT1 PE=1 SV=6" 9.75 1333 - 1.12E+06 - - - -2.4407 - 3.239 0.512 - 951.1 1 2 0 -0.0027 14 0 0 0 4.58E+08 6.77E+06 - - - 5.7711 0.9999 221125_WJC_METTL3_EV_vs_WT_F10.03722.03722.3 0.000212 Dec-44 R.R[166.11]EEAAVDAQQQK[136.11].R sp|Q15149|PLEC_HUMAN 1 1389.6967 2.37 137558 3722 3 1389.693825 464.2395 Plectin OS=Homo sapiens OX=9606 GN=PLEC PE=1 SV=3 4.68 1333.1 - 773536 - - - -2.0875 - 2.064 0.444 - 221.8 1 2 0 -0.0029 12 0 0 0 1.18E+07 4.98E+06 - - - 5.498 0.9745 221125_WJC_METTL3_EV_vs_WT_F10.03723.03723.2 0.00122 18-Nov R.IR[166.11]DVTNNQEK[136.11].H "sp|Q9Y2L1|RRP44_HUMAN,tr|F2Z2C0|F2Z2C0_HUMAN" 2 1233.6432 1.52 137559 3723 2 1233.642352 617.8289 Exosome complex exonuclease RRP44 OS=Homo sapiens OX=9606 GN=DIS3 PE=1 SV=2 6.07 1333.2 - 660528 - - - -0.715 - 2.244 0.059 - 365.7 1 2 1 -0.0009 10 0 0 0 6.72E+06 4.41E+06 - - - 1.7326 0.9503 221125_WJC_METTL3_EV_vs_WT_F10.03724.03724.3 0.00879 Nov-44 Y.TKQDGEC[160.03]GTLSK.G sp|Q5D862|FILA2_HUMAN 1 1322.6136 105.04 137560 3724 3 1322.611544 441.8785 Filaggrin-2 OS=Homo sapiens OX=9606 GN=FLG2 PE=1 SV=1 5.73 1333.3 - 657707 - - - -1.5772 - 2.105 0.432 - 184.1 1 1 1 -0.0021 12 0 0 0 4.92E+06 4.68E+04 - - - 5.4189 0.9984 221125_WJC_METTL3_EV_vs_WT_F10.03725.03725.2 0.000107 18-Sep K.KPSQTASYER.L sp|Q8WUF5|IASPP_HUMAN 1 1165.5728 4.2 137561 3725 2 1165.569533 583.7937 RelA-associated inhibitor OS=Homo sapiens OX=9606 GN=PPP1R13L PE=1 SV=4 8.59 1333.5 - 400081 - - - -2.7609 - 1.883 0.318 - 271.6 1 2 0 -0.0032 10 0 0 0 3.07E+06 7.30E+05 - - - 3.1553 0.9991 221125_WJC_METTL3_EV_vs_WT_F10.03732.03732.3 0.00208 Oct-36 R.NDRGDQVPNR.K "sp|Q8IX12|CCAR1_HUMAN,tr|F5H2E6|F5H2E6_HUMAN,tr|F5H1H2|F5H1H2_HUMAN,tr|A0A0C4DGG8|A0A0C4DGG8_HUMAN,tr|F5H3E1|F5H3E1_HUMAN" 5 1169.5537 2.4 137566 3732 3 1169.551838 390.8585 Cell division cycle and apoptosis regulator protein 1 OS=Homo sapiens OX=9606 GN=CCAR1 PE=1 SV=2 5.96 1334.4 - 2.89E+06 - - - -1.6322 - 2.288 0.352 - 167.9 1 2 1 -0.0019 10 0 0 0 2.27E+07 9.48E+06 - - - 4.8811 0.9999 221125_WJC_METTL3_EV_vs_WT_F10.03736.03736.2 2.91E-06 20-Nov R.TGSQGQC[160.03]TQVR[166.11].V sp|P62857|RS28_HUMAN 1 1230.5651 0.62 137570 3736 2 1230.564561 616.2898 40S ribosomal protein S28 OS=Homo sapiens OX=9606 GN=RPS28 PE=1 SV=1 7.91 1334.7 - 696031 - - - -0.4006 - 2.505 0.496 - 526.6 1 2 0 -0.0005 11 0 0 0 2.59E+06 4.16E+06 - - - 5.1885 0.9746 221125_WJC_METTL3_EV_vs_WT_F10.03737.03737.2 0.00252 16-Jul L.GK[136.11]PHTVPC[160.03]K[136.11].V "sp|P15880|RS2_HUMAN,tr|I3L404|I3L404_HUMAN,tr|E9PM36|E9PM36_HUMAN,tr|E9PMM9|E9PMM9_HUMAN,tr|H0YEN5|H0YEN5_HUMAN" 5 1038.5615 1.09 137571 3737 2 1038.560108 520.288 40S ribosomal protein S2 OS=Homo sapiens OX=9606 GN=RPS2 PE=1 SV=2 9.31 1334.8 - 516082 - - - -1.374 - 1.495 0.456 - 157.8 1 1 0 -0.0014 9 0 0 0 9.57E+06 8.77E+06 - - - 3.5719 0.9967 221125_WJC_METTL3_EV_vs_WT_F10.03739.03739.2 0.02 18-Aug K.IGKPHTVPC[160.03]K.V "sp|P15880|RS2_HUMAN,tr|I3L404|I3L404_HUMAN,tr|E9PM36|E9PM36_HUMAN,tr|E9PPT0|E9PPT0_HUMAN,tr|E9PMM9|E9PMM9_HUMAN,tr|H0YEN5|H0YEN5_HUMAN" 6 1135.6172 0.9 137573 3739 2 1135.615532 568.8159 40S ribosomal protein S2 OS=Homo sapiens OX=9606 GN=RPS2 PE=1 SV=2 9.31 1335.1 - 410837 - - - -1.4679 - 1.286 0.269 - 164.4 1 2 0 -0.0017 10 0 0 0 6.80E+06 7.57E+06 - - - 1.7294 0.9996 221125_WJC_METTL3_EV_vs_WT_F10.03743.03743.2 0.00217 22-Sep K.R[166.11]EPAEQPGDGER[166.11].T "sp|Q14151|SAFB2_HUMAN,sp|Q15424|SAFB1_HUMAN" 2 1359.6282 1.37 137577 3743 2 1359.627369 680.8214 Scaffold attachment factor B2 OS=Homo sapiens OX=9606 GN=SAFB2 PE=1 SV=1 4.41 1335.6 - 115078 - - - -0.6083 - 1.677 0.401 - 103 1 2 0 -0.0008 12 0 0 0 4.32E+06 3.16E+06 - - - 3.3629 0.9789 221125_WJC_METTL3_EV_vs_WT_F10.03750.03750.3 7.97E-05 Oct-56 K.APKPDGPGGGPGGSH.M "sp|P35637|FUS_HUMAN,tr|H3BPE7|H3BPE7_HUMAN" 2 1286.6004 1.05 137582 3750 3 1286.598719 429.8741 RNA-binding protein FUS OS=Homo sapiens OX=9606 GN=FUS PE=1 SV=1 6.79 1336.4 - 450640 - - - -1.2778 - 1.811 0.41 - 128.8 1 1 0 -0.0016 15 0 0 0 4.34E+07 4.15E+07 - - - 4.6603 0.9996 221125_WJC_METTL3_EV_vs_WT_F10.03760.03760.3 2.75E-05 Aug-36 R.GNHEC[160.03]ASINR.L "sp|P62136|PP1A_HUMAN,sp|P62140|PP1B_HUMAN,sp|P36873|PP1G_HUMAN,tr|C9JP48|C9JP48_HUMAN,tr|E7ETD8|E7ETD8_HUMAN,tr|A0A087WYY5|A0A087WYY5_HUMAN,tr|A0A7I2V4F7|A0A7I2V4F7_HUMAN,tr|F8W0W8|F8W0W8_HUMAN,tr|F8VYE8|F8VYE8_HUMAN,tr|F8VR82|F8VR82_HUMAN,tr|E9PMD7|E9PMD7_HUMAN" 11 1156.5044 1.26 137590 3760 3 1156.50226 386.5087 Serine\threonine-protein phosphatase PP1-alpha catalytic subunit OS=Homo sapiens OX=9606 GN=PPP1CA PE=1 SV=1 6.74 1337.5 - 1.67E+06 - - - -1.8106 - 1.846 0.356 - 141.9 1 2 0 -0.0021 10 0 0 0 4.17E+07 3.31E+07 - - - 4.2988 1 221125_WJC_METTL3_EV_vs_WT_F10.03763.03763.2 1.49E-10 22-Dec K.VDC[160.03]TANTNTC[160.03]NK[136.11].Y "sp|P30101|PDIA3_HUMAN,tr|H7BZJ3|H7BZJ3_HUMAN" 2 1404.5853 0.84 137593 3763 2 1404.583856 703.2999 Protein disulfide-isomerase A3 OS=Homo sapiens OX=9606 GN=PDIA3 PE=1 SV=4 5.79 1337.9 - 458734 - - - -1.0373 - 2.764 0.758 - 658.5 1 2 0 -0.0015 12 0 0 0 1.63E+07 1.94E+07 - - - 7.3142 0.9869 221125_WJC_METTL3_EV_vs_WT_F10.03766.03766.3 3.79E-05 Nov-44 K.ETQSPEQVKSEK.L "sp|Q9NYF8|BCLF1_HUMAN,tr|E9PKI6|E9PKI6_HUMAN,tr|A0A1W2PQ43|A0A1W2PQ43_HUMAN,tr|E9PK91|E9PK91_HUMAN,tr|E9PK09|E9PK09_HUMAN,tr|E9PQN2|E9PQN2_HUMAN" 6 1388.6783 2.73 137596 3766 3 1388.671541 463.9001 Bcl-2-associated transcription factor 1 OS=Homo sapiens OX=9606 GN=BCLAF1 PE=1 SV=2 4.79 1338.3 - 369991 - - - -4.8946 - 1.975 0.374 - 164.1 1 2 1 -0.0068 12 0 0 0 6.46E+07 2.37E+07 - - - 4.5943 1 221125_WJC_METTL3_EV_vs_WT_F10.03767.03767.2 2.99E-10 13/22 K.VDC[160.03]TANTNTC[160.03]NK.Y "sp|P30101|PDIA3_HUMAN,tr|H7BZJ3|H7BZJ3_HUMAN" 2 1396.5711 0.84 137597 3767 2 1396.56922 699.2928 Protein disulfide-isomerase A3 OS=Homo sapiens OX=9606 GN=PDIA3 PE=1 SV=4 5.79 1338.4 - 269247 - - - -1.3555 - 2.841 0.678 - 770.1 1 2 0 -0.0019 12 0 0 0 1.63E+07 1.94E+07 - - - 6.7955 0.9892 221125_WJC_METTL3_EV_vs_WT_F10.03769.03769.3 0.132 Aug-44 K.ETQSPEQVK[136.11]SEK[136.11].L "sp|Q9NYF8|BCLF1_HUMAN,tr|E9PKI6|E9PKI6_HUMAN,tr|A0A1W2PQ43|A0A1W2PQ43_HUMAN,tr|E9PK91|E9PK91_HUMAN,tr|E9PK09|E9PK09_HUMAN,tr|E9PQN2|E9PQN2_HUMAN" 6 1404.7067 2.73 137599 3769 3 1404.70776 469.2429 Bcl-2-associated transcription factor 1 OS=Homo sapiens OX=9606 GN=BCLAF1 PE=1 SV=2 4.79 1338.7 - 187327 - - - 0.7276 - 1.789 0.23 - 96.1 1 2 1 0.001 12 0 0 0 6.45E+07 2.37E+07 - - - 2.7163 0.9995 221125_WJC_METTL3_EV_vs_WT_F10.03776.03776.3 0.00548 Oct-36 R.GNHEC[160.03]ASINR[166.11].L "sp|P62136|PP1A_HUMAN,sp|P62140|PP1B_HUMAN,sp|P36873|PP1G_HUMAN,tr|C9JP48|C9JP48_HUMAN,tr|E7ETD8|E7ETD8_HUMAN,tr|A0A087WYY5|A0A087WYY5_HUMAN,tr|A0A7I2V4F7|A0A7I2V4F7_HUMAN,tr|F8W0W8|F8W0W8_HUMAN,tr|F8VYE8|F8VYE8_HUMAN,tr|F8VR82|F8VR82_HUMAN,tr|E9PMD7|E9PMD7_HUMAN" 11 1166.5126 1.25 137604 3776 3 1166.510009 389.8448 Serine\threonine-protein phosphatase PP1-alpha catalytic subunit OS=Homo sapiens OX=9606 GN=PPP1CA PE=1 SV=1 6.74 1339.6 - 5.50E+06 - - - -2.2417 - 2.004 0.348 - 212.6 1 2 0 -0.0026 10 0 0 0 4.16E+07 3.31E+07 - - - 4.4493 0.9954 221125_WJC_METTL3_EV_vs_WT_F10.03778.03778.3 0.000975 Oct-36 K.VEDKEKELEK.L sp|Q5JSZ5|PRC2B_HUMAN 1 1245.6452 1.78 137606 3778 3 1245.642692 416.2224 Protein PRRC2B OS=Homo sapiens OX=9606 GN=PRRC2B PE=1 SV=2 4.59 1339.7 - 2.92E+06 - - - -2.0511 - 1.916 0.298 - 164.2 1 2 2 -0.0026 10 0 0 0 1.84E+07 1.03E+07 - - - 3.7607 1 221125_WJC_METTL3_EV_vs_WT_F10.03780.03780.3 8.88E-07 18/48 R.LENNENK[136.11]PVTNSR[166.11].D sp|Q9Y5A9|YTHD2_HUMAN 1 1531.771 1.64 137608 3780 3 1531.770487 511.5976 YTH domain-containing family protein 2 OS=Homo sapiens OX=9606 GN=YTHDF2 PE=1 SV=2 6.14 1339.8 - 2.65E+06 - - - -0.3049 - 3 0.549 - 425.6 1 2 0 -0.0005 13 0 0 0 3.04E+09 1.85E+09 - - - 7.6393 0.9945 221125_WJC_METTL3_EV_vs_WT_F10.03785.03785.2 0.0003 20-Oct R.HQEEESETEED.E sp|Q5D862|FILA2_HUMAN 1 1360.4903 - 137613 3785 2 1360.489504 681.2524 Filaggrin-2 OS=Homo sapiens OX=9606 GN=FLG2 PE=1 SV=1 3.92 1340.3 - 691066 - - - -0.5579 - 2.023 0.618 - 363.2 1 1 0 -0.0008 11 0 0 0 - - - - - 5.5114 0.9997 221125_WJC_METTL3_EV_vs_WT_F10.03790.03790.2 0.000275 24-Jul R.SSSGPPHETAAPK.R "sp|Q9Y618|NCOR2_HUMAN,tr|C9JQE8|C9JQE8_HUMAN,tr|C9J7T7|C9J7T7_HUMAN,tr|C9JE98|C9JE98_HUMAN,tr|C9J0Q5|C9J0Q5_HUMAN,tr|A0A384DVL6|A0A384DVL6_HUMAN" 6 1264.6048 0.18 137618 3790 2 1264.604585 633.3097 Nuclear receptor corepressor 2 OS=Homo sapiens OX=9606 GN=NCOR2 PE=1 SV=3 6.47 1340.9 - 155230 - - - -0.1542 - 1.697 0.414 - 101.2 1 2 0 -0.0002 13 0 0 0 2.29E+06 1.28E+07 - - - 3.4561 1 221125_WJC_METTL3_EV_vs_WT_F10.03792.03792.2 3.09E-09 14/24 R.LENNENKPVTNSR.D sp|Q9Y5A9|YTHD2_HUMAN 1 1513.7485 1.62 137620 3792 2 1513.744195 757.8815 YTH domain-containing family protein 2 OS=Homo sapiens OX=9606 GN=YTHDF2 PE=1 SV=2 6.14 1341.2 - 104534 - - - -2.8334 - 2.868 0.617 - 453.7 1 2 0 -0.0043 13 0 0 0 1.89E+08 1.16E+08 - - - 6.3009 0.9999 221125_WJC_METTL3_EV_vs_WT_F10.03796.03796.3 0.000705 Dec-48 R.SSSGPPHETAAPK.R "sp|Q9Y618|NCOR2_HUMAN,tr|C9JQE8|C9JQE8_HUMAN,tr|C9J7T7|C9J7T7_HUMAN,tr|C9JE98|C9JE98_HUMAN,tr|C9J0Q5|C9J0Q5_HUMAN,tr|A0A384DVL6|A0A384DVL6_HUMAN" 6 1264.6048 3.32 137622 3796 3 1264.60193 422.5422 Nuclear receptor corepressor 2 OS=Homo sapiens OX=9606 GN=NCOR2 PE=1 SV=3 6.47 1341.6 - 3.14E+06 - - - -2.2537 - 2.7 0.466 - 221.8 1 2 0 -0.0029 13 0 0 0 5.45E+07 1.64E+07 - - - 6.4276 1 221125_WJC_METTL3_EV_vs_WT_F10.03799.03799.2 4.34E-09 14/24 R.LENNENK[136.11]PVTNSR[166.11].D sp|Q9Y5A9|YTHD2_HUMAN 1 1531.771 1.62 137625 3799 2 1531.768277 766.8928 YTH domain-containing family protein 2 OS=Homo sapiens OX=9606 GN=YTHDF2 PE=1 SV=2 6.14 1341.8 - 2.03E+06 - - - -1.7477 - 3.098 0.615 - 475.9 1 2 0 -0.0027 13 0 0 0 1.89E+08 1.16E+08 - - - 6.4847 0.9996 221125_WJC_METTL3_EV_vs_WT_F10.03800.03800.3 0.00218 Sep-40 K.FQNNSEDNVKK.L "sp|Q8IWJ2|GCC2_HUMAN,tr|B8ZZA5|B8ZZA5_HUMAN,tr|B8ZZW2|B8ZZW2_HUMAN" 3 1321.6262 1.35 137626 3800 3 1321.62289 441.5494 GRIP and coiled-coil domain-containing protein 2 OS=Homo sapiens OX=9606 GN=GCC2 PE=1 SV=4 6.07 1341.9 - 1.25E+06 - - - -2.537 - 1.696 0.427 - 68.7 1 2 0 -0.0034 11 0 0 0 9.51E+06 7.07E+06 - - - 4.8004 0.9998 221125_WJC_METTL3_EV_vs_WT_F10.03801.03801.2 2.01E-05 18-Dec R.GNHEC[160.03]ASINR[166.11].L "sp|P62136|PP1A_HUMAN,sp|P62140|PP1B_HUMAN,sp|P36873|PP1G_HUMAN,tr|C9JP48|C9JP48_HUMAN,tr|E7ETD8|E7ETD8_HUMAN,tr|A0A087WYY5|A0A087WYY5_HUMAN,tr|A0A7I2V4F7|A0A7I2V4F7_HUMAN,tr|F8W0W8|F8W0W8_HUMAN,tr|F8VYE8|F8VYE8_HUMAN,tr|F8VR82|F8VR82_HUMAN,tr|E9PMD7|E9PMD7_HUMAN" 11 1166.5126 1.24 137627 3801 2 1166.51054 584.2636 Serine\threonine-protein phosphatase PP1-alpha catalytic subunit OS=Homo sapiens OX=9606 GN=PPP1CA PE=1 SV=1 6.74 1342 - 809406 - - - -1.7865 - 1.743 0.567 - 351.5 1 2 0 -0.0021 10 0 0 0 5.41E+06 4.38E+06 - - - 4.7791 0.9997 221125_WJC_METTL3_EV_vs_WT_F10.03802.03802.3 3.39E-05 13/48 R.LENNENKPVTNSR[166.11].D sp|Q9Y5A9|YTHD2_HUMAN 1 1523.7568 - 137628 3802 3 1523.755282 508.9262 YTH domain-containing family protein 2 OS=Homo sapiens OX=9606 GN=YTHDF2 PE=1 SV=2 6.14 1342.1 - 738298 - - - -0.966 - 2.326 0.328 - 191.2 2 2 0 -0.0015 13 0 0 0 - - - - - 4.3459 1 221125_WJC_METTL3_EV_vs_WT_F10.03804.03804.3 1.60E-08 17/52 K.ADDLGK[136.11]GGNEESTK[136.11].T "sp|P00441|SODC_HUMAN,tr|H7BYH4|H7BYH4_HUMAN" 2 1435.6762 1.52 137630 3804 3 1435.673812 479.566 Superoxide dismutase [Cu-Zn] OS=Homo sapiens OX=9606 GN=SOD1 PE=1 SV=2 4.32 1342.4 - 697595 - - - -1.6403 - 3.4 0.607 - 407.8 1 2 1 -0.0024 14 0 0 0 4.09E+07 2.69E+07 - - - 8.559 0.99 221125_WJC_METTL3_EV_vs_WT_F10.03807.03807.2 3.15E-08 20-Nov E.NNENKPVTNSR.D sp|Q9Y5A9|YTHD2_HUMAN 1 1271.6218 1.91 137633 3807 2 1271.619448 636.8182 YTH domain-containing family protein 2 OS=Homo sapiens OX=9606 GN=YTHDF2 PE=1 SV=2 8.75 1342.8 - 321860 - - - -1.8708 - 2.314 0.582 - 338.9 1 1 0 -0.0024 11 0 0 0 2.38E+07 1.25E+07 - - - 5.6085 0.9895 221125_WJC_METTL3_EV_vs_WT_F10.03808.03808.2 0.000522 28-Sep K.APKPDGPGGGPGGSH.M "sp|P35637|FUS_HUMAN,tr|H3BPE7|H3BPE7_HUMAN" 2 1286.6004 1.45 137634 3808 2 1286.598908 644.3075 RNA-binding protein FUS OS=Homo sapiens OX=9606 GN=FUS PE=1 SV=1 6.79 1342.9 - 235714 - - - -1.1309 - 1.913 0.54 - 193 1 1 0 -0.0015 15 0 0 0 1.98E+06 1.37E+06 - - - 4.6238 0.9954 221125_WJC_METTL3_EV_vs_WT_F10.03814.03814.3 7.68E-08 13/52 K.ADDLGKGGNEESTK.T "sp|P00441|SODC_HUMAN,tr|H7BYH4|H7BYH4_HUMAN" 2 1419.6478 1.43 137638 3814 3 1419.636818 474.2232 Superoxide dismutase [Cu-Zn] OS=Homo sapiens OX=9606 GN=SOD1 PE=1 SV=2 4.32 1343.4 - 2.91E+06 - - - -7.7125 - 2.839 0.615 - 170.4 1 2 1 -0.0109 14 0 0 0 3.83E+07 2.68E+07 - - - 8.1666 0.9913 221125_WJC_METTL3_EV_vs_WT_F10.03815.03815.2 0.00212 14/22 L.ENNENKPVTNSR.D sp|Q9Y5A9|YTHD2_HUMAN 1 1400.6644 2.26 137639 3815 2 1400.662284 701.3395 YTH domain-containing family protein 2 OS=Homo sapiens OX=9606 GN=YTHDF2 PE=1 SV=2 6.24 1343.5 - 1.80E+06 - - - -1.525 - 2.561 0.527 - 461.2 1 1 0 -0.0021 12 0 0 0 2.53E+07 1.12E+07 - - - 5.4071 1 221125_WJC_METTL3_EV_vs_WT_F10.03816.03816.3 4.14E-10 14/40 K.EC[160.03]PSSHPEPTR[166.11].A "sp|O00443|P3C2A_HUMAN,tr|A0A0C4DGF9|A0A0C4DGF9_HUMAN,tr|E9PPP3|E9PPP3_HUMAN" 3 1305.5647 1.83 137640 3816 3 1305.560515 436.1955 Phosphatidylinositol 4-phosphate 3-kinase C2 domain-containing subunit alpha OS=Homo sapiens OX=9606 GN=PIK3C2A PE=1 SV=2 5.4 1343.6 - 1.49E+06 - - - -3.2201 - 2.642 0.644 - 289 1 2 0 -0.0042 11 0 0 0 7.59E+07 4.16E+07 - - - 8.4788 0.9994 221125_WJC_METTL3_EV_vs_WT_F10.03823.03823.3 5.95E-05 13/44 R.AQR[166.11]PQSC[160.03]TSVGR[166.11].V sp|Q9NYZ3|GTSE1_HUMAN 1 1365.6686 1.12 137647 3823 3 1365.662608 456.2302 G2 and S phase-expressed protein 1 OS=Homo sapiens OX=9606 GN=GTSE1 PE=1 SV=3 10.35 1344.5 - 399862 - - - -4.403 - 2.404 0.426 - 223.3 1 2 0 -0.006 12 0 0 0 4.43E+06 3.97E+06 - - - 5.7191 0.9999 221125_WJC_METTL3_EV_vs_WT_F10.03830.03830.3 2.25E-07 Dec-40 K.EC[160.03]PSSHPEPTR.A "sp|O00443|P3C2A_HUMAN,tr|A0A0C4DGF9|A0A0C4DGF9_HUMAN,tr|E9PPP3|E9PPP3_HUMAN" 3 1295.5564 1.83 137652 3830 3 1295.552423 432.8594 Phosphatidylinositol 4-phosphate 3-kinase C2 domain-containing subunit alpha OS=Homo sapiens OX=9606 GN=PIK3C2A PE=1 SV=2 5.4 1345.2 - 2.84E+06 - - - -3.1075 - 2.386 0.483 - 224.4 1 2 0 -0.004 11 0 0 0 7.59E+07 4.16E+07 - - - 6.3943 0.964 221125_WJC_METTL3_EV_vs_WT_F10.03831.03831.2 1.24E-06 13/22 L.ENNENK[136.11]PVTNSR[166.11].D sp|Q9Y5A9|YTHD2_HUMAN 1 1418.6869 2.26 137653 3831 2 1418.681807 710.3507 YTH domain-containing family protein 2 OS=Homo sapiens OX=9606 GN=YTHDF2 PE=1 SV=2 6.24 1345.3 - 1.63E+06 - - - -3.5829 - 2.531 0.537 - 412.3 1 1 0 -0.0051 12 0 0 0 2.53E+07 1.12E+07 - - - 5.449 0.9547 221125_WJC_METTL3_EV_vs_WT_F10.03832.03832.2 7.14E-09 13/20 E.NNENK[136.11]PVTNSR[166.11].D sp|Q9Y5A9|YTHD2_HUMAN 1 1289.6443 1.91 137654 3832 2 1289.639579 645.8294 YTH domain-containing family protein 2 OS=Homo sapiens OX=9606 GN=YTHDF2 PE=1 SV=2 8.75 1345.4 - 1.54E+06 - - - -3.6584 - 2.345 0.502 - 501.3 1 1 0 -0.0047 11 0 0 0 2.38E+07 1.25E+07 - - - 5.0529 1 221125_WJC_METTL3_EV_vs_WT_F10.03838.03838.3 1.09E-08 15/40 K.K[136.11]GAVEC[160.03]C[160.03]PNC[160.03]R[166.11].G sp|P31689|DNJA1_HUMAN 1 1367.5863 0.47 137658 3838 3 1367.582242 456.8694 DnaJ homolog subfamily A member 1 OS=Homo sapiens OX=9606 GN=DNAJA1 PE=1 SV=2 7.96 1346.2 - 1.66E+06 - - - -2.9892 - 2.947 0.558 - 345.4 1 2 0 -0.0041 11 0 0 0 4.24E+07 9.03E+07 - - - 7.8303 1 221125_WJC_METTL3_EV_vs_WT_F10.03844.03844.3 1.66E-06 16/40 K.KGAVEC[160.03]C[160.03]PNC[160.03]R.G sp|P31689|DNJA1_HUMAN 1 1349.5639 0.47 137662 3844 3 1349.560776 450.8619 DnaJ homolog subfamily A member 1 OS=Homo sapiens OX=9606 GN=DNAJA1 PE=1 SV=2 7.96 1347 - 2.31E+06 - - - -2.2852 - 2.799 0.565 - 388.9 1 2 0 -0.0031 11 0 0 0 4.24E+07 9.03E+07 - - - 7.7623 0.9977 221125_WJC_METTL3_EV_vs_WT_F10.03851.03851.2 0.0135 14-Jun K.HYTEAIK[136.11]R[166.11].N sp|P31948|STIP1_HUMAN 1 1034.5628 0.83 137667 3851 2 1034.561593 518.2887 Stress-induced-phosphoprotein 1 OS=Homo sapiens OX=9606 GN=STIP1 PE=1 SV=1 8.6 1347.9 - 287203 - - - -1.1657 - 1.124 0.338 - 123.9 1 2 0 -0.0012 8 0 0 0 3.18E+06 3.82E+06 - - - 1.8896 1 221125_WJC_METTL3_EV_vs_WT_F10.03854.03854.2 2.75E-12 20-Dec K.K[136.11]GAVEC[160.03]C[160.03]PNC[160.03]R[166.11].G sp|P31689|DNJA1_HUMAN 1 1367.5863 0.39 137668 3854 2 1367.583147 684.8004 DnaJ homolog subfamily A member 1 OS=Homo sapiens OX=9606 GN=DNAJA1 PE=1 SV=2 7.96 1348.3 - 860958 - - - -2.3275 - 2.71 0.778 - 487.1 1 2 0 -0.0032 11 0 0 0 4.09E+06 1.04E+07 - - - 7.4833 1 221125_WJC_METTL3_EV_vs_WT_F10.03856.03856.2 4.01E-09 14/20 K.KGAVEC[160.03]C[160.03]PNC[160.03]R.G sp|P31689|DNJA1_HUMAN 1 1349.5639 0.39 137670 3856 2 1349.560606 675.7892 DnaJ homolog subfamily A member 1 OS=Homo sapiens OX=9606 GN=DNAJA1 PE=1 SV=2 7.96 1348.6 - 358988 - - - -2.4111 - 2.453 0.725 - 813 1 2 0 -0.0033 11 0 0 0 4.09E+06 1.04E+07 - - - 6.8223 0.9999 221125_WJC_METTL3_EV_vs_WT_F10.03866.03866.3 6.68E-06 Oct-36 R.K[136.11]DSETGENIR[166.11].Q "sp|P38646|GRP75_HUMAN,tr|A0A7I2V2S7|A0A7I2V2S7_HUMAN,tr|A0A7I2V2G2|A0A7I2V2G2_HUMAN,tr|A0A7I2V3F7|A0A7I2V3F7_HUMAN,tr|A0A7I2YQB2|A0A7I2YQB2_HUMAN,tr|D6RCD7|D6RCD7_HUMAN" 6 1165.5694 0.48 137676 3866 3 1165.567059 389.5304 "Stress-70 protein, mitochondrial OS=Homo sapiens OX=9606 GN=HSPA9 PE=1 SV=2" 4.68 1349.7 - 3.59E+07 - - - -2.0085 - 2.105 0.437 - 259.7 1 2 0 -0.0023 10 0 0 0 5.18E+08 1.09E+09 - - - 5.5852 0.9521 221125_WJC_METTL3_EV_vs_WT_F10.03869.03869.3 1.65 Oct-44 R.AQEALSHTEQSK[136.11].S sp|O75146|HIP1R_HUMAN 1 1335.651 1.27 137679 3869 3 1335.649218 446.2243 Huntingtin-interacting protein 1-related protein OS=Homo sapiens OX=9606 GN=HIP1R PE=1 SV=2 5.4 1350 - 616662 - - - -1.3402 - 1.439 0.128 - 92 1 2 0 -0.0018 12 0 0 0 1.09E+07 8.53E+06 - - - 0.9754 0.9997 221125_WJC_METTL3_EV_vs_WT_F10.03872.03872.2 0.0344 18-Oct R.KDSETGENIR.Q "sp|P38646|GRP75_HUMAN,tr|A0A7I2V2S7|A0A7I2V2S7_HUMAN,tr|A0A7I2V2G2|A0A7I2V2G2_HUMAN,tr|A0A7I2V3F7|A0A7I2V3F7_HUMAN,tr|A0A7I2YQB2|A0A7I2YQB2_HUMAN,tr|D6RCD7|D6RCD7_HUMAN" 6 1147.5469 0.44 137681 3872 2 1147.545377 574.7807 "Stress-70 protein, mitochondrial OS=Homo sapiens OX=9606 GN=HSPA9 PE=1 SV=2" 4.68 1350.4 - 3.52E+06 - - - -1.3533 - 2.053 0.406 - 325.3 1 2 0 -0.0016 10 0 0 0 1.80E+08 4.12E+08 - - - 4.047 0.9999 221125_WJC_METTL3_EV_vs_WT_F10.03876.03876.3 0.000156 Nov-44 K.ASPQENGPAVHK.G "sp|Q5JSZ5|PRC2B_HUMAN,tr|A0A804HIM8|A0A804HIM8_HUMAN" 2 1233.6102 2.41 137684 3876 3 1233.608627 412.2107 Protein PRRC2B OS=Homo sapiens OX=9606 GN=PRRC2B PE=1 SV=2 6.79 1350.7 - 3.32E+06 - - - -1.2743 - 2.028 0.49 - 170.9 1 2 0 -0.0016 12 0 0 0 9.00E+07 3.74E+07 - - - 5.9624 0.9947 221125_WJC_METTL3_EV_vs_WT_F10.03880.03880.3 0.0885 Nov-36 K.IKEGAENLRK.V "sp|Q16513|PKN2_HUMAN,tr|B1AL79|B1AL79_HUMAN" 2 1156.6564 1.07 137688 3880 3 1156.655917 386.5594 Serine\threonine-protein kinase N2 OS=Homo sapiens OX=9606 GN=PKN2 PE=1 SV=1 8.59 1351.2 - 255261 - - - -0.4357 - 2.026 0.234 - 131.6 1 2 1 -0.0005 10 0 0 0 7.30E+06 6.84E+06 - - - 3.2107 0.9925 221125_WJC_METTL3_EV_vs_WT_F10.03888.03888.3 0.0254 Aug-36 K.IADR[166.11]EDEYK[136.11]K[136.11].H "sp|O75533|SF3B1_HUMAN,tr|B4DGZ4|B4DGZ4_HUMAN,tr|A0A494C1M2|A0A494C1M2_HUMAN" 3 1291.6619 1.08 137694 3888 3 1291.661989 431.5612 Splicing factor 3B subunit 1 OS=Homo sapiens OX=9606 GN=SF3B1 PE=1 SV=3 4.78 1352 - 3.31E+06 - - - 0.1068 - 1.342 0.32 - 77.1 1 2 1 0.0001 10 0 0 0 5.59E+07 5.17E+07 - - - 2.9667 0.9998 221125_WJC_METTL3_EV_vs_WT_F10.03893.03893.2 1.07E-05 22-Sep K.ASPQENGPAVHK.G "sp|Q5JSZ5|PRC2B_HUMAN,tr|A0A804HIM8|A0A804HIM8_HUMAN" 2 1233.6102 2.76 137699 3893 2 1233.609633 617.8124 Protein PRRC2B OS=Homo sapiens OX=9606 GN=PRRC2B PE=1 SV=2 6.79 1352.4 - 508430 - - - -0.4588 - 1.725 0.513 - 265.5 1 2 0 -0.0006 12 0 0 0 7.82E+06 2.83E+06 - - - 4.2644 0.9907 221125_WJC_METTL3_EV_vs_WT_F10.03895.03895.2 9.50E-06 18-Nov S.PQENGPAVHK[136.11].G "sp|Q5JSZ5|PRC2B_HUMAN,tr|A0A804HIM8|A0A804HIM8_HUMAN" 2 1083.5553 5.83 137701 3895 2 1083.553861 542.7849 Protein PRRC2B OS=Homo sapiens OX=9606 GN=PRRC2B PE=1 SV=2 7.17 1352.6 - 248041 - - - -1.2884 - 2.144 0.515 - 399 1 1 0 -0.0014 10 0 0 0 2.30E+07 3.94E+06 - - - 4.9732 0.9994 221125_WJC_METTL3_EV_vs_WT_F10.03898.03898.2 0.000887 20-Jun R.C[160.03]QPK[136.11]PSEEAPK[136.11].C sp|Q9H6F5|CCD86_HUMAN 1 1285.6307 9.64 137704 3898 2 1285.631863 643.8226 Coiled-coil domain-containing protein 86 OS=Homo sapiens OX=9606 GN=CCDC86 PE=1 SV=1 6.14 1353 - 124827 - - - 0.8758 - 1.341 0.44 - 140.4 1 2 0 0.0011 11 0 0 0 1.52E+07 1.58E+06 - - - 3.0842 0.9116 221125_WJC_METTL3_EV_vs_WT_F10.03903.03903.3 0.00634 Oct-32 L.ADREDEYKK.H "sp|O75533|SF3B1_HUMAN,tr|B4DGZ4|B4DGZ4_HUMAN,tr|A0A494C1M2|A0A494C1M2_HUMAN" 3 1152.5411 1.11 137707 3903 3 1152.539937 385.1876 Splicing factor 3B subunit 1 OS=Homo sapiens OX=9606 GN=SF3B1 PE=1 SV=3 4.78 1353.6 - 2.06E+06 - - - -1.0238 - 1.643 0.407 - 121.3 1 1 1 -0.0012 9 0 0 0 1.48E+07 1.33E+07 - - - 4.5737 0.9999 221125_WJC_METTL3_EV_vs_WT_F10.03906.03906.3 0.000109 Nov-44 K.NGDIC[160.03]ETSGK[136.11]PK[136.11].T "sp|Q16637|SMN_HUMAN,tr|E7EQZ4|E7EQZ4_HUMAN,tr|B4DP61|B4DP61_HUMAN,tr|A0A1W2PRV5|A0A1W2PRV5_HUMAN" 4 1320.6315 0.7 137710 3906 3 1320.631512 441.2178 Survival motor neuron protein OS=Homo sapiens OX=9606 GN=SMN1 PE=1 SV=1 6.06 1353.9 - 1.22E+06 - - - 0.0356 - 2.06 0.426 - 157.8 1 2 0 0 12 0 0 0 3.25E+07 4.61E+07 - - - 5.2927 0.9999 221125_WJC_METTL3_EV_vs_WT_F10.03907.03907.3 0.000295 Nov-40 K.NENSNDPELK[136.11]K[136.11].L "sp|Q8IXB1|DJC10_HUMAN,tr|A0A7P0Z431|A0A7P0Z431_HUMAN,tr|A0A7P0TAQ9|A0A7P0TAQ9_HUMAN" 3 1302.6387 2.09 137711 3907 3 1302.638294 435.2202 DnaJ homolog subfamily C member 10 OS=Homo sapiens OX=9606 GN=DNAJC10 PE=1 SV=2 4.68 1353.9 - 1.13E+06 - - - -0.2802 - 1.977 0.442 - 177.3 1 2 0 -0.0004 11 0 0 0 4.67E+07 2.24E+07 - - - 5.404 0.9937 221125_WJC_METTL3_EV_vs_WT_F10.03910.03910.3 0.00425 Sep-32 R.YPDHSVDRR.E sp|Q15424|SAFB1_HUMAN 1 1143.5421 0.02 137714 3910 3 1143.537871 382.188 Scaffold attachment factor B1 OS=Homo sapiens OX=9606 GN=SAFB PE=1 SV=4 6.75 1354.2 - 751531 - - - -3.7156 - 1.462 0.325 - 118.7 1 2 0 -0.0042 9 0 0 0 1.57E+07 6.63E+08 - - - 3.3069 0.9996 221125_WJC_METTL3_EV_vs_WT_F10.03916.03916.3 7.88E-06 14/44 R.LR[166.11]AETEQGEQQR[166.11].Q sp|Q15149|PLEC_HUMAN 1 1463.7232 0.05 137718 3916 3 1463.719824 488.915 Plectin OS=Homo sapiens OX=9606 GN=PLEC PE=1 SV=3 4.79 1355 - 1.11E+06 - - - -2.2784 - 2.732 0.431 - 380.9 1 2 1 -0.0033 12 0 0 0 4.23E+05 8.41E+06 - - - 6.1301 0.9995 221125_WJC_METTL3_EV_vs_WT_F10.03922.03922.3 0.012 Nov-36 R.SEIQAEQDR[166.11]K[136.11].L "sp|Q16891|MIC60_HUMAN,tr|B9A067|B9A067_HUMAN,tr|C9J406|C9J406_HUMAN,tr|H7C463|H7C463_HUMAN" 4 1220.6116 0.71 137724 3922 3 1220.609251 407.8778 MICOS complex subunit MIC60 OS=Homo sapiens OX=9606 GN=IMMT PE=1 SV=1 4.68 1355.7 - 464789 - - - -1.9236 - 1.745 0.36 - 142 1 2 0 -0.0023 10 0 0 0 4.90E+06 6.91E+06 - - - 4.179 1 221125_WJC_METTL3_EV_vs_WT_F10.03934.03934.2 7.76E-07 22-Dec K.NGDIC[160.03]ETSGKPK.T "sp|Q16637|SMN_HUMAN,tr|E7EQZ4|E7EQZ4_HUMAN,tr|B4DP61|B4DP61_HUMAN,tr|A0A1W2PRV5|A0A1W2PRV5_HUMAN" 4 1304.6031 1.38 137734 3934 2 1304.598294 653.3088 Survival motor neuron protein OS=Homo sapiens OX=9606 GN=SMN1 PE=1 SV=1 6.06 1357.3 - 663210 - - - -3.6571 - 2.63 0.624 - 609.5 1 2 0 -0.0048 12 0 0 0 4.33E+06 3.14E+06 - - - 6.1927 0.9852 221125_WJC_METTL3_EV_vs_WT_F10.03935.03935.2 4.29E-05 22-Sep L.TQSVGGDSSADR[166.11].L "sp|Q86U44|MTA70_HUMAN,tr|H0YFV6|H0YFV6_HUMAN" 2 1188.5246 0.02 137735 3935 2 1188.522728 595.2696 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 4.21 1357.4 - 611413 - - - -1.5986 - 1.793 0.529 - 294.8 1 1 0 -0.0019 12 0 0 0 5.89E+04 3.56E+06 - - - 4.4839 1 221125_WJC_METTL3_EV_vs_WT_F10.03937.03937.2 1.65E-07 22-Nov K.QQNVQSASQDEK[136.11].L "sp|Q2M389|WASC4_HUMAN,tr|A0A087X256|A0A087X256_HUMAN" 2 1368.6361 0.76 137737 3937 2 1368.637119 685.3253 WASH complex subunit 4 OS=Homo sapiens OX=9606 GN=WASHC4 PE=1 SV=2 4.37 1357.7 - 302732 - - - 0.7548 - 2.256 0.618 - 474.7 1 2 0 0.001 12 0 0 0 1.45E+06 1.91E+06 - - - 5.7459 0.8664 221125_WJC_METTL3_EV_vs_WT_F10.03938.03938.2 1.78 16-May R.GEADR[166.11]DTYR[166.11].R "sp|P46783|RS10_HUMAN,tr|F6U211|F6U211_HUMAN,tr|A0A1W2PQS6|A0A1W2PQS6_HUMAN,tr|A0A2R8YFH6|A0A2R8YFH6_HUMAN,tr|A0A2R8Y7H1|A0A2R8Y7H1_HUMAN,tr|S4R435|S4R435_HUMAN" 6 1101.4954 0.95 137738 3938 2 1101.494928 551.755 40S ribosomal protein S10 OS=Homo sapiens OX=9606 GN=RPS10 PE=1 SV=1 4.56 1357.8 - 270026 - - - -0.4203 - 0.963 0.202 - 66 1 2 1 -0.0005 9 0 0 0 1.36E+06 1.44E+06 - - - 0.4238 1 221125_WJC_METTL3_EV_vs_WT_F10.03943.03943.2 5.99E-10 13/26 R.YGQQGSGSGQSPSR.G sp|Q86YZ3|HORN_HUMAN 1 1394.6175 1229.28 137741 3943 2 1394.615554 698.316 Hornerin OS=Homo sapiens OX=9606 GN=HRNR PE=1 SV=2 8.75 1358.4 - 1.74E+06 - - - -1.3731 - 2.767 0.691 - 501.6 1 2 0 -0.0019 14 0 0 0 8.72E+07 7.09E+04 - - - 6.6982 0.9993 221125_WJC_METTL3_EV_vs_WT_F10.03944.03944.2 0.0132 16-Nov K.K[136.11]IEISQHAK[136.11].Y "sp|P61513|RL37A_HUMAN,tr|E9PEL3|E9PEL3_HUMAN,tr|G5E9R3|G5E9R3_HUMAN,tr|C9J4Z3|C9J4Z3_HUMAN,tr|M0R2L6|M0R2L6_HUMAN,tr|M0R0A1|M0R0A1_HUMAN,tr|Q6P4E4|Q6P4E4_HUMAN" 7 1068.6262 0.91 137742 3944 2 1068.624941 535.3204 60S ribosomal protein L37a OS=Homo sapiens OX=9606 GN=RPL37A PE=1 SV=2 8.6 1358.5 - 1.84E+06 - - - -1.2193 - 2.283 0.203 - 351.8 1 2 0 -0.0013 9 0 0 0 1.71E+07 1.89E+07 - - - 2.9281 0.9994 221125_WJC_METTL3_EV_vs_WT_F10.03945.03945.2 0.0524 16-Dec K.KIEISQHAK.Y "sp|P61513|RL37A_HUMAN,tr|E9PEL3|E9PEL3_HUMAN,tr|G5E9R3|G5E9R3_HUMAN,tr|C9J4Z3|C9J4Z3_HUMAN,tr|M0R2L6|M0R2L6_HUMAN,tr|M0R0A1|M0R0A1_HUMAN,tr|Q6P4E4|Q6P4E4_HUMAN" 7 1052.5978 0.91 137743 3945 2 1052.596373 527.3062 60S ribosomal protein L37a OS=Homo sapiens OX=9606 GN=RPL37A PE=1 SV=2 8.6 1358.6 - 1.38E+06 - - - -1.3975 - 2.154 0.264 - 380.5 1 2 0 -0.0015 9 0 0 0 1.71E+07 1.89E+07 - - - 3.2104 0.9998 221125_WJC_METTL3_EV_vs_WT_F10.03946.03946.3 0.000197 13/56 K.EVTNASAAGNK[136.11]APGK[136.11].G sp|Q15054|DPOD3_HUMAN 1 1429.7496 0.66 137744 3946 3 1429.746926 477.5905 DNA polymerase delta subunit 3 OS=Homo sapiens OX=9606 GN=POLD3 PE=1 SV=2 8.69 1358.7 - 919151 - - - -1.8745 - 2.314 0.526 - 165.7 1 2 1 -0.0027 15 0 0 0 2.99E+06 4.55E+06 - - - 6.5928 0.997 221125_WJC_METTL3_EV_vs_WT_F10.03948.03948.3 0.0706 Oct-44 K.GQDMETEAHQNK.L "sp|Q15363|TMED2_HUMAN,tr|F5GX39|F5GX39_HUMAN" 2 1386.5834 1.76 137746 3948 3 1386.582145 463.2017 Transmembrane emp24 domain-containing protein 2 OS=Homo sapiens OX=9606 GN=TMED2 PE=1 SV=1 4.65 1358.9 - 357367 - - - -0.8993 - 1.514 0.257 - 115.9 1 2 0 -0.0012 12 0 0 0 2.89E+06 1.64E+06 - - - 2.5546 0.9998 221125_WJC_METTL3_EV_vs_WT_F10.03951.03951.2 1.13E-08 22-Sep K.NGDIC[160.03]ETSGK[136.11]PK[136.11].T "sp|Q16637|SMN_HUMAN,tr|E7EQZ4|E7EQZ4_HUMAN,tr|B4DP61|B4DP61_HUMAN,tr|A0A1W2PRV5|A0A1W2PRV5_HUMAN" 4 1320.6315 1.28 137749 3951 2 1320.63225 661.323 Survival motor neuron protein OS=Homo sapiens OX=9606 GN=SMN1 PE=1 SV=1 6.06 1359.3 - 242479 - - - 0.5944 - 1.984 0.502 - 342.8 1 2 0 0.0008 12 0 0 0 4.03E+06 3.14E+06 - - - 4.5512 0.9999 221125_WJC_METTL3_EV_vs_WT_F10.03954.03954.3 3.29E-07 14/40 R.NAEQYK[136.11]DQADK[136.11].A sp|P35579|MYH9_HUMAN 1 1324.623 1.32 137750 3954 3 1324.621481 442.5483 Myosin-9 OS=Homo sapiens OX=9606 GN=MYH9 PE=1 SV=4 4.56 1359.7 - 7.25E+06 - - - -1.1535 - 2.426 0.555 - 326.8 1 2 1 -0.0015 11 0 0 0 7.00E+07 5.31E+07 - - - 7.2449 0.9998 221125_WJC_METTL3_EV_vs_WT_F10.03955.03955.3 0.000115 Oct-40 R.NAEQYKDQADK.A sp|P35579|MYH9_HUMAN 1 1308.5946 1.35 137751 3955 3 1308.593801 437.2055 Myosin-9 OS=Homo sapiens OX=9606 GN=MYH9 PE=1 SV=4 4.56 1359.8 - 6.66E+06 - - - -0.6175 - 1.953 0.517 - 166.6 1 2 1 -0.0008 11 0 0 0 7.20E+07 5.34E+07 - - - 6.2054 0.9992 221125_WJC_METTL3_EV_vs_WT_F10.03956.03956.3 2.21E-05 16/36 R.SVHK[136.11]VEPITK[136.11].H "sp|P25787|PSA2_HUMAN,tr|A0A024RA52|A0A024RA52_HUMAN,tr|A0A7I2V2H3|A0A7I2V2H3_HUMAN" 3 1152.6838 0.02 137752 3956 3 1152.682455 385.2352 Proteasome subunit alpha type-2 OS=Homo sapiens OX=9606 GN=PSMA2 PE=1 SV=2 8.34 1359.8 - 1.60E+06 - - - -1.1313 - 3.018 0.263 - 375.3 1 2 1 -0.0013 10 0 0 0 1.91E+05 1.01E+07 - - - 4.6977 0.9985 221125_WJC_METTL3_EV_vs_WT_F10.03958.03958.3 0.000779 Oct-44 K.ETSDGEKETIQK.T "sp|Q86W92|LIPB1_HUMAN,tr|F5GZP6|F5GZP6_HUMAN" 2 1363.6467 1.52 137754 3958 3 1363.645606 455.5562 Liprin-beta-1 OS=Homo sapiens OX=9606 GN=PPFIBP1 PE=1 SV=2 4.41 1360 - 1.08E+06 - - - -0.8052 - 2.003 0.33 - 117 1 2 1 -0.0011 12 0 0 0 6.60E+06 4.35E+06 - - - 4.1443 1 221125_WJC_METTL3_EV_vs_WT_F10.03960.03960.2 0.000254 14/20 R.NAEQYK[136.11]DQADK[136.11].A sp|P35579|MYH9_HUMAN 1 1324.623 1.2 137756 3960 2 1324.622015 663.3188 Myosin-9 OS=Homo sapiens OX=9606 GN=MYH9 PE=1 SV=4 4.56 1360.2 - 856982 - - - -0.7504 - 2.853 0.573 - 974.8 1 2 1 -0.001 11 0 0 0 8.94E+06 7.48E+06 - - - 6.109 1 221125_WJC_METTL3_EV_vs_WT_F10.03962.03962.2 7.68E-07 20-Dec R.NAEQYKDQADK.A sp|P35579|MYH9_HUMAN 1 1308.5946 1.2 137758 3962 2 1308.593226 655.3046 Myosin-9 OS=Homo sapiens OX=9606 GN=MYH9 PE=1 SV=4 4.56 1360.4 - 739110 - - - -1.0569 - 2.681 0.556 - 585.6 1 2 1 -0.0014 11 0 0 0 8.94E+06 7.48E+06 - - - 5.8151 1 221125_WJC_METTL3_EV_vs_WT_F10.03965.03965.2 3.15E-13 18/36 K.EGTGSTATSSSSTAGAAGK.G "sp|O15372|EIF3H_HUMAN,tr|B3KS98|B3KS98_HUMAN,tr|E5RHC7|E5RHC7_HUMAN,tr|A0A087WZK9|A0A087WZK9_HUMAN,tr|E5RH59|E5RH59_HUMAN,tr|E5RFW7|E5RFW7_HUMAN,tr|E5RFH0|E5RFH0_HUMAN,tr|E5RGU4|E5RGU4_HUMAN" 8 1626.7333 1.96 137761 3965 2 1626.73202 814.3739 Eukaryotic translation initiation factor 3 subunit H OS=Homo sapiens OX=9606 GN=EIF3H PE=1 SV=1 6.1 1360.8 - 387087 - - - -0.7789 - 3.732 0.721 - 931.3 1 2 0 -0.0013 19 0 0 0 5.66E+07 2.89E+07 - - - 7.6037 1 221125_WJC_METTL3_EV_vs_WT_F10.03969.03969.2 5.25E-13 18/36 K.EGTGSTATSSSSTAGAAGK[136.11].G "sp|O15372|EIF3H_HUMAN,tr|B3KS98|B3KS98_HUMAN,tr|E5RHC7|E5RHC7_HUMAN,tr|A0A087WZK9|A0A087WZK9_HUMAN,tr|E5RH59|E5RH59_HUMAN,tr|E5RFW7|E5RFW7_HUMAN,tr|E5RFH0|E5RFH0_HUMAN,tr|E5RGU4|E5RGU4_HUMAN" 8 1634.7475 1.96 137765 3969 2 1634.747936 818.381 Eukaryotic translation initiation factor 3 subunit H OS=Homo sapiens OX=9606 GN=EIF3H PE=1 SV=1 6.1 1361.4 - 232620 - - - 0.2747 - 3.692 0.752 - 1146.5 1 2 0 0.0004 19 0 0 0 5.66E+07 2.89E+07 - - - 7.8064 0.9777 221125_WJC_METTL3_EV_vs_WT_F10.03971.03971.2 0.0609 16-Jul R.AEEWHGRPK.A sp|Q8IU81|I2BP1_HUMAN 1 1108.5414 3.84 137767 3971 2 1108.546044 555.278 Interferon regulatory factor 2-binding protein 1 OS=Homo sapiens OX=9606 GN=IRF2BP1 PE=1 SV=1 6.8 1361.6 - 169527 - - - 4.1974 - 1.26 0.279 - 196.6 1 2 0 0.0047 9 0 0 0 2.54E+06 6.60E+05 - - - 1.7689 0.9995 221125_WJC_METTL3_EV_vs_WT_F10.03972.03972.2 0.00338 20-Sep K.ISRPGDSDDSR.S "sp|P14866|HNRPL_HUMAN,tr|M0QYL7|M0QYL7_HUMAN,tr|B4DVF8|B4DVF8_HUMAN,tr|M0R1W6|M0R1W6_HUMAN,tr|A0A3B3ITJ4|A0A3B3ITJ4_HUMAN,tr|M0QXS5|M0QXS5_HUMAN" 6 1203.548 1.35 137768 3972 2 1203.545902 602.7813 Heterogeneous nuclear ribonucleoprotein L OS=Homo sapiens OX=9606 GN=HNRNPL PE=1 SV=2 4.43 1361.7 - 154525 - - - -1.7374 - 1.94 0.392 - 212.6 1 2 0 -0.0021 11 0 0 0 9.86E+07 7.30E+07 - - - 3.7284 0.9841 221125_WJC_METTL3_EV_vs_WT_F10.03982.03982.3 0.0319 15/36 R.SVHKVEPITK.H "sp|P25787|PSA2_HUMAN,tr|A0A024RA52|A0A024RA52_HUMAN,tr|A0A7I2V2H3|A0A7I2V2H3_HUMAN" 3 1136.6554 -1 137777 3982 3 1137.659211 379.8924 Proteasome subunit alpha type-2 OS=Homo sapiens OX=9606 GN=PSMA2 PE=1 SV=2 8.34 1362.8 - 811099 - - - 883.163 - 2.408 0.366 - 286.8 1 2 1 1.0039 10 0 0 0 0.00E+00 0.00E+00 - - - 4.9089 1 221125_WJC_METTL3_EV_vs_WT_F10.03983.03983.3 4.90E-07 16/72 K.EGTGSTATSSSSTAGAAGK.G "sp|O15372|EIF3H_HUMAN,tr|B3KS98|B3KS98_HUMAN,tr|E5RHC7|E5RHC7_HUMAN,tr|A0A087WZK9|A0A087WZK9_HUMAN,tr|E5RH59|E5RH59_HUMAN,tr|E5RFW7|E5RFW7_HUMAN,tr|E5RFH0|E5RFH0_HUMAN,tr|E5RGU4|E5RGU4_HUMAN" 8 1626.7333 1.84 137778 3983 3 1626.732503 543.2517 Eukaryotic translation initiation factor 3 subunit H OS=Homo sapiens OX=9606 GN=EIF3H PE=1 SV=1 6.1 1363 - 675544 - - - -0.4819 - 2.969 0.55 - 349.6 1 2 0 -0.0008 19 0 0 0 5.06E+06 2.74E+06 - - - 7.3453 0.9986 221125_WJC_METTL3_EV_vs_WT_F10.03986.03986.2 1.19E-05 18-Sep K.TKYDEETTAK.A "sp|Q13948|CASP_HUMAN,sp|P39880|CUX1_HUMAN,tr|A0A2R8Y8D0|A0A2R8Y8D0_HUMAN,tr|A0A2R8Y852|A0A2R8Y852_HUMAN,tr|A0A2R8YDI1|A0A2R8YDI1_HUMAN" 5 1184.5561 -1 137781 3986 2 1184.555398 593.2853 Protein CASP OS=Homo sapiens OX=9606 GN=CUX1 PE=1 SV=2 4.68 1363.4 - 452425 - - - -0.5909 - 1.794 0.574 - 160 1 2 1 -0.0007 10 0 0 0 0.00E+00 0.00E+00 - - - 4.9117 0.9999 221125_WJC_METTL3_EV_vs_WT_F10.03987.03987.3 1.96E-05 14/72 K.EGTGSTATSSSSTAGAAGK[136.11].G "sp|O15372|EIF3H_HUMAN,tr|B3KS98|B3KS98_HUMAN,tr|E5RHC7|E5RHC7_HUMAN,tr|A0A087WZK9|A0A087WZK9_HUMAN,tr|E5RH59|E5RH59_HUMAN,tr|E5RFW7|E5RFW7_HUMAN,tr|E5RFH0|E5RFH0_HUMAN,tr|E5RGU4|E5RGU4_HUMAN" 8 1634.7475 1.89 137782 3987 3 1634.746446 545.9231 Eukaryotic translation initiation factor 3 subunit H OS=Homo sapiens OX=9606 GN=EIF3H PE=1 SV=1 6.1 1363.5 - 423787 - - - -0.6368 - 2.462 0.441 - 146.7 1 2 0 -0.001 19 0 0 0 5.18E+06 2.74E+06 - - - 5.6699 0.9822 221125_WJC_METTL3_EV_vs_WT_F10.03990.03990.2 0.018 18-Nov L.SR[166.11]PGDSDDSR[166.11].S "sp|P14866|HNRPL_HUMAN,tr|M0QYL7|M0QYL7_HUMAN,tr|B4DVF8|B4DVF8_HUMAN,tr|M0R1W6|M0R1W6_HUMAN,tr|A0A3B3ITJ4|A0A3B3ITJ4_HUMAN,tr|M0QXS5|M0QXS5_HUMAN" 6 1110.4805 1.35 137785 3990 2 1110.479301 556.2475 Heterogeneous nuclear ribonucleoprotein L OS=Homo sapiens OX=9606 GN=HNRNPL PE=1 SV=2 4.43 1363.9 - 222111 - - - -1.0518 - 2.014 0.381 - 366.8 1 1 0 -0.0012 10 0 0 0 6.52E+07 4.84E+07 - - - 3.809 0.9975 221125_WJC_METTL3_EV_vs_WT_F10.04003.04003.3 0.0403 Oct-44 R.QLEDGDQPESKK.L "sp|Q92945|FUBP2_HUMAN,tr|M0R0I5|M0R0I5_HUMAN,tr|M0R0C6|M0R0C6_HUMAN,tr|A0A087WTP3|A0A087WTP3_HUMAN" 4 1372.647 0.56 137796 4003 3 1372.645449 458.5563 Far upstream element-binding protein 2 OS=Homo sapiens OX=9606 GN=KHSRP PE=1 SV=4 4.32 1365 - 1.30E+06 - - - -1.1576 - 1.753 0.236 - 150.3 1 2 0 -0.0016 12 0 0 0 1.38E+07 2.48E+07 - - - 2.7266 1 221125_WJC_METTL3_EV_vs_WT_F10.04011.04011.2 5.80E-07 17/22 K.TEQTEKAEEETR.M "sp|Q6Y7W6|GGYF2_HUMAN,tr|A0A7I2V3H7|A0A7I2V3H7_HUMAN,tr|I1E4Y6|I1E4Y6_HUMAN,tr|A0A7I2V516|A0A7I2V516_HUMAN,tr|A0A7I2V3H0|A0A7I2V3H0_HUMAN,tr|C9JHW1|C9JHW1_HUMAN,tr|A0A7I2V361|A0A7I2V361_HUMAN,tr|E7ESB6|E7ESB6_HUMAN" 8 1449.6583 3.04 137804 4011 2 1449.655823 725.8364 GRB10-interacting GYF protein 2 OS=Homo sapiens OX=9606 GN=GIGYF2 PE=1 SV=1 4.32 1365.9 - 409347 - - - -1.7301 - 3.037 0.636 - 1214.5 1 2 1 -0.0025 12 0 0 0 1.46E+07 4.82E+06 - - - 6.6606 0.9999 221125_WJC_METTL3_EV_vs_WT_F10.04016.04016.3 1.09E-05 16/44 K.TEQTEKAEEETR.M "sp|Q6Y7W6|GGYF2_HUMAN,tr|A0A7I2V3H7|A0A7I2V3H7_HUMAN,tr|I1E4Y6|I1E4Y6_HUMAN,tr|A0A7I2V516|A0A7I2V516_HUMAN,tr|A0A7I2V3H0|A0A7I2V3H0_HUMAN,tr|C9JHW1|C9JHW1_HUMAN,tr|A0A7I2V361|A0A7I2V361_HUMAN,tr|E7ESB6|E7ESB6_HUMAN" 8 1449.6583 2.87 137807 4016 3 1449.656024 484.2267 GRB10-interacting GYF protein 2 OS=Homo sapiens OX=9606 GN=GIGYF2 PE=1 SV=1 4.32 1366.6 - 1.24E+07 - - - -1.5914 - 3.114 0.599 - 479.5 1 2 1 -0.0023 12 0 0 0 1.01E+08 3.51E+07 - - - 8.3662 0.9784 221125_WJC_METTL3_EV_vs_WT_F10.04017.04017.2 2.78 12-May K.KDMMDIK.Y sp|Q96RL7|VP13A_HUMAN 1 879.4194 27.69 137808 4017 2 879.421062 440.717 Vacuolar protein sorting-associated protein 13A OS=Homo sapiens OX=9606 GN=VPS13A PE=1 SV=2 5.96 1366.7 - 8.22E+06 - - - 1.8785 - 1.194 0.136 - 145.9 1 2 0 0.0017 7 0 0 0 8.35E+07 3.01E+06 - - - 0.6068 1 221125_WJC_METTL3_EV_vs_WT_F10.04021.04021.3 1.98E-05 15/52 K.ELQNAHNGVNQASK.E sp|Q6UWP8|SBSN_HUMAN 1 1508.7332 999 137812 4021 3 1508.732565 503.9183 Suprabasin OS=Homo sapiens OX=9606 GN=SBSN PE=1 SV=2 6.85 1367.1 - 1.42E+06 - - - -0.3997 - 2.383 0.47 - 244.8 1 2 0 -0.0006 14 0 0 0 3.88E+07 0.00E+00 - - - 6.0876 0.9995 221125_WJC_METTL3_EV_vs_WT_F10.04022.04022.3 0.000246 14/36 K.EILKEQENRK.G "sp|Q99497|PARK7_HUMAN,tr|K7EN27|K7EN27_HUMAN,tr|K7ELW0|K7ELW0_HUMAN" 3 1285.699 2.12 137813 4022 3 1285.697423 429.5736 Parkinson disease protein 7 OS=Homo sapiens OX=9606 GN=PARK7 PE=1 SV=2 6.33 1367.2 - 1.21E+06 - - - -1.2375 - 2.515 0.356 - 224.7 1 2 1 -0.0016 10 0 0 0 2.32E+07 1.09E+07 - - - 5.202 0.9427 221125_WJC_METTL3_EV_vs_WT_F10.04025.04025.2 0.000126 13/18 L.SRPGDSDDSR.S "sp|P14866|HNRPL_HUMAN,tr|M0QYL7|M0QYL7_HUMAN,tr|B4DVF8|B4DVF8_HUMAN,tr|M0R1W6|M0R1W6_HUMAN,tr|A0A3B3ITJ4|A0A3B3ITJ4_HUMAN,tr|M0QXS5|M0QXS5_HUMAN" 6 1090.4639 1.36 137816 4025 2 1090.460194 546.2392 Heterogeneous nuclear ribonucleoprotein L OS=Homo sapiens OX=9606 GN=HNRNPL PE=1 SV=2 4.43 1367.6 - 892301 - - - -3.4251 - 2.07 0.444 - 538.5 1 1 0 -0.0037 10 0 0 0 6.50E+07 4.79E+07 - - - 4.35 1 221125_WJC_METTL3_EV_vs_WT_F10.04027.04027.2 1.12E-07 14/22 K.TEQTEK[136.11]AEEETR[166.11].M "sp|Q6Y7W6|GGYF2_HUMAN,tr|A0A7I2V3H7|A0A7I2V3H7_HUMAN,tr|I1E4Y6|I1E4Y6_HUMAN,tr|A0A7I2V516|A0A7I2V516_HUMAN,tr|A0A7I2V3H0|A0A7I2V3H0_HUMAN,tr|C9JHW1|C9JHW1_HUMAN,tr|A0A7I2V361|A0A7I2V361_HUMAN,tr|E7ESB6|E7ESB6_HUMAN" 8 1467.6808 3.04 137818 4027 2 1467.677374 734.8477 GRB10-interacting GYF protein 2 OS=Homo sapiens OX=9606 GN=GIGYF2 PE=1 SV=1 4.32 1367.9 - 597466 - - - -2.335 - 2.896 0.621 - 764.4 1 2 1 -0.0034 12 0 0 0 1.46E+07 4.82E+06 - - - 6.4244 0.9999 221125_WJC_METTL3_EV_vs_WT_F10.04032.04032.3 0.00277 Nov-44 R.QLEDGDQPESK[136.11]K[136.11].L "sp|Q92945|FUBP2_HUMAN,tr|M0R0I5|M0R0I5_HUMAN,tr|M0R0C6|M0R0C6_HUMAN,tr|A0A087WTP3|A0A087WTP3_HUMAN" 4 1388.6754 1.15 137822 4032 3 1388.673219 463.8991 Far upstream element-binding protein 2 OS=Homo sapiens OX=9606 GN=KHSRP PE=1 SV=4 4.32 1368.5 - 1.29E+06 - - - -1.5979 - 1.868 0.449 - 193.3 1 2 0 -0.0022 12 0 0 0 9.95E+06 8.62E+06 - - - 5.2773 0.9524 221125_WJC_METTL3_EV_vs_WT_F10.04035.04035.2 2.66 18-May R.C[160.03]YGVASSHLK.T sp|P48552|NRIP1_HUMAN 1 1120.5335 272.7 137824 4035 2 1120.530505 561.274 Nuclear receptor-interacting protein 1 OS=Homo sapiens OX=9606 GN=NRIP1 PE=1 SV=2 8.21 1368.8 - 2.12E+06 - - - -2.6987 - 1.016 0.179 - 77.9 1 2 0 -0.003 10 0 0 0 1.99E+07 7.30E+04 - - - 0.4065 0.9981 221125_WJC_METTL3_EV_vs_WT_F10.04048.04048.3 0.000597 Sep-36 K.NRPEDYQGGR.T sp|Q15084|PDIA6_HUMAN 1 1190.5428 1.14 137835 4048 3 1190.540674 397.8549 Protein disulfide-isomerase A6 OS=Homo sapiens OX=9606 GN=PDIA6 PE=1 SV=1 6.07 1370.2 - 2.48E+06 - - - -1.8261 - 1.771 0.268 - 143.9 1 2 0 -0.0022 10 0 0 0 1.42E+08 1.24E+08 - - - 3.1965 0.995 221125_WJC_METTL3_EV_vs_WT_F10.04050.04050.2 0.166 16-Sep R.HQQLSGLHK.Q sp|P98175|RBM10_HUMAN 1 1046.5621 3.37 137837 4050 2 1046.559258 524.2883 RNA-binding protein 10 OS=Homo sapiens OX=9606 GN=RBM10 PE=1 SV=3 8.76 1370.4 - 511011 - - - -2.7414 - 1.593 0.233 - 157.3 1 2 0 -0.0029 9 0 0 0 5.18E+06 1.54E+06 - - - 2.1081 0.9997 221125_WJC_METTL3_EV_vs_WT_F10.04058.04058.3 1.16E-07 13/44 K.TEQTEK[136.11]AEEETR[166.11].M "sp|Q6Y7W6|GGYF2_HUMAN,tr|A0A7I2V3H7|A0A7I2V3H7_HUMAN,tr|I1E4Y6|I1E4Y6_HUMAN,tr|A0A7I2V516|A0A7I2V516_HUMAN,tr|A0A7I2V3H0|A0A7I2V3H0_HUMAN,tr|C9JHW1|C9JHW1_HUMAN,tr|A0A7I2V361|A0A7I2V361_HUMAN,tr|E7ESB6|E7ESB6_HUMAN" 8 1467.6808 2.87 137843 4058 3 1467.676476 490.2342 GRB10-interacting GYF protein 2 OS=Homo sapiens OX=9606 GN=GIGYF2 PE=1 SV=1 4.32 1371.4 - 1.02E+06 - - - -2.9468 - 2.68 0.536 - 283 1 2 1 -0.0043 12 0 0 0 1.01E+08 3.51E+07 - - - 7.2472 0.9998 221125_WJC_METTL3_EV_vs_WT_F10.04061.04061.3 5.06E-05 18/56 K.K[136.11]LEGNSPQGSNQGVK[136.11].L sp|P61006|RAB8A_HUMAN 1 1557.8082 1.25 137846 4061 3 1557.805115 520.2767 Ras-related protein Rab-8A OS=Homo sapiens OX=9606 GN=RAB8A PE=1 SV=1 8.59 1371.8 - 630532 - - - -1.9701 - 2.459 0.377 - 413.2 1 2 0 -0.0031 15 0 0 0 5.82E+07 4.67E+07 - - - 5.0901 0.9999 221125_WJC_METTL3_EV_vs_WT_F10.04066.04066.3 4.34E-07 16/56 K.SR[166.11]PGTASSSGGSIAR[166.11].G "sp|Q9Y618|NCOR2_HUMAN,tr|C9J7T7|C9J7T7_HUMAN,tr|C9JE98|C9JE98_HUMAN,tr|C9J0Q5|C9J0Q5_HUMAN,tr|A0A384DVL6|A0A384DVL6_HUMAN" 5 1409.7126 2.03 137849 4066 3 1409.708754 470.9115 Nuclear receptor corepressor 2 OS=Homo sapiens OX=9606 GN=NCOR2 PE=1 SV=3 12 1372.4 - 2.33E+06 - - - -2.724 - 2.928 0.525 - 408 1 2 0 -0.0038 15 0 0 0 8.90E+07 4.39E+07 - - - 7.1955 0.9997 221125_WJC_METTL3_EV_vs_WT_F10.04069.04069.2 7.17E-06 18-Dec K.NR[166.11]PEDYQGGR[166.11].T sp|Q15084|PDIA6_HUMAN 1 1210.5594 1.45 137852 4069 2 1210.557489 606.287 Protein disulfide-isomerase A6 OS=Homo sapiens OX=9606 GN=PDIA6 PE=1 SV=1 6.07 1372.7 - 842192 - - - -1.5687 - 2.151 0.392 - 294.8 1 2 0 -0.0019 10 0 0 0 2.85E+07 1.96E+07 - - - 4.0737 0.9963 221125_WJC_METTL3_EV_vs_WT_F10.04071.04071.2 0.00261 18-Jun K.HTANYDTEER[166.11].V "sp|Q99590|SCAFB_HUMAN,tr|F8VXG7|F8VXG7_HUMAN,tr|A0A0A0MTP7|A0A0A0MTP7_HUMAN" 3 1244.5297 1.27 137854 4071 2 1244.525055 623.2721 Protein SCAF11 OS=Homo sapiens OX=9606 GN=SCAF11 PE=1 SV=2 4.65 1372.9 - 284102 - - - -3.7436 - 1.496 0.394 - 79.9 1 2 0 -0.0047 10 0 0 0 4.28E+06 3.37E+06 - - - 3.0739 0.9998 221125_WJC_METTL3_EV_vs_WT_F10.04074.04074.3 0.02 15/56 K.KLEGNSPQGSNQGVK.L sp|P61006|RAB8A_HUMAN 1 1541.7798 1.25 137855 4074 3 1541.775984 514.9339 Ras-related protein Rab-8A OS=Homo sapiens OX=9606 GN=RAB8A PE=1 SV=1 8.59 1373.3 - 2.37E+06 - - - -2.4647 - 2.512 0.396 - 259.2 1 2 0 -0.0038 15 0 0 0 5.82E+07 4.67E+07 - - - 5.3574 0.9998 221125_WJC_METTL3_EV_vs_WT_F10.04076.04076.3 0.00113 Oct-32 K.LNC[160.03]AFHHNR[166.11].G "sp|O75152|ZC11A_HUMAN,tr|E9PBY7|E9PBY7_HUMAN,tr|A0A1W2PPR9|A0A1W2PPR9_HUMAN,tr|E9PQ61|E9PQ61_HUMAN" 4 1177.5439 4.44 137857 4076 3 1177.541431 393.5219 Zinc finger CCCH domain-containing protein 11A OS=Homo sapiens OX=9606 GN=ZC3H11A PE=1 SV=3 8.27 1373.5 - 761345 - - - -2.067 - 2.056 0.382 - 153 1 2 0 -0.0024 9 0 0 0 3.55E+07 8.00E+06 - - - 4.9705 0.9996 221125_WJC_METTL3_EV_vs_WT_F10.04078.04078.3 0.000636 14/48 K.VSSAEGAAKEEPK.R "sp|P05114|HMGN1_HUMAN,tr|F2Z2W6|F2Z2W6_HUMAN,tr|F2Z2Y5|F2Z2Y5_HUMAN,tr|A6NEL0|A6NEL0_HUMAN,tr|H7BXJ5|H7BXJ5_HUMAN,tr|A0A494C035|A0A494C035_HUMAN" 6 1301.6463 1.06 137859 4078 3 1301.644658 434.8894 Non-histone chromosomal protein HMG-14 OS=Homo sapiens OX=9606 GN=HMGN1 PE=1 SV=3 4.79 1373.7 - 660524 - - - -1.2692 - 2.826 0.371 - 287.7 1 2 1 -0.0017 13 0 0 0 1.81E+07 1.71E+07 - - - 5.4925 0.9806 221125_WJC_METTL3_EV_vs_WT_F10.04079.04079.3 0.0316 Aug-44 K.ELKTDSSPNQAR.A "sp|P26599|PTBP1_HUMAN,tr|A0A6Q8PEX4|A0A6Q8PEX4_HUMAN,tr|A6NLN1|A6NLN1_HUMAN,tr|A0A087WU68|A0A087WU68_HUMAN,tr|K7ES59|K7ES59_HUMAN,tr|A0A7I2V4H6|A0A7I2V4H6_HUMAN,tr|A0A7I2V621|A0A7I2V621_HUMAN" 7 1344.6634 1.07 137860 4079 3 1344.662945 449.2284 Polypyrimidine tract-binding protein 1 OS=Homo sapiens OX=9606 GN=PTBP1 PE=1 SV=1 6.17 1373.9 - 528701 - - - -0.3064 - 1.66 0.214 - 124.3 1 2 1 -0.0004 12 0 0 0 4.87E+07 4.56E+07 - - - 2.3306 1 221125_WJC_METTL3_EV_vs_WT_F10.04080.04080.2 1.29E-12 13/26 R.GPVSSTSDSSTNC[160.03]K.N sp|Q8NDV7|TNR6A_HUMAN 1 1425.6042 3.06 137861 4080 2 1425.602837 713.8094 Trinucleotide repeat-containing gene 6A protein OS=Homo sapiens OX=9606 GN=TNRC6A PE=1 SV=2 5.83 1374 - 525096 - - - -0.9477 - 2.833 0.633 - 426.9 1 2 0 -0.0014 14 0 0 0 4.88E+06 1.59E+06 - - - 6.3291 0.9999 221125_WJC_METTL3_EV_vs_WT_F10.04081.04081.3 7.06E-06 15/48 K.KAESTESIGSSEK.T "sp|Q9BZI7|REN3B_HUMAN,tr|A0A1B0GVA2|A0A1B0GVA2_HUMAN" 2 1351.6467 1.95 137862 4081 3 1351.643179 451.5562 Regulator of nonsense transcripts 3B OS=Homo sapiens OX=9606 GN=UPF3B PE=1 SV=1 4.79 1374.1 - 422478 - - - -2.6079 - 2.843 0.508 - 304.8 1 2 0 -0.0035 13 0 0 0 8.47E+06 4.34E+06 - - - 7.0356 0.9797 221125_WJC_METTL3_EV_vs_WT_F10.04082.04082.2 0.102 28-May K.SRPGTASSSGGSIAR.G "sp|Q9Y618|NCOR2_HUMAN,tr|C9J7T7|C9J7T7_HUMAN,tr|C9JE98|C9JE98_HUMAN,tr|C9J0Q5|C9J0Q5_HUMAN,tr|A0A384DVL6|A0A384DVL6_HUMAN" 5 1389.6961 2.47 137863 4082 2 1389.693038 695.8553 Nuclear receptor corepressor 2 OS=Homo sapiens OX=9606 GN=NCOR2 PE=1 SV=3 12 1374.3 - 401701 - - - -2.1703 - 1.18 0.211 - 14.7 4 2 0 -0.003 15 0 0 0 6.06E+06 2.46E+06 - - - 0.7365 0.9999 221125_WJC_METTL3_EV_vs_WT_F10.04085.04085.3 0.00252 Nov-40 K.ISRPGDSDDSR.S "sp|P14866|HNRPL_HUMAN,tr|M0QYL7|M0QYL7_HUMAN,tr|B4DVF8|B4DVF8_HUMAN,tr|M0R1W6|M0R1W6_HUMAN,tr|A0A3B3ITJ4|A0A3B3ITJ4_HUMAN,tr|M0QXS5|M0QXS5_HUMAN" 6 1203.548 1.2 137865 4085 3 1203.546271 402.1899 Heterogeneous nuclear ribonucleoprotein L OS=Homo sapiens OX=9606 GN=HNRNPL PE=1 SV=2 4.43 1374.6 - 3.31E+07 - - - -1.4308 - 1.923 0.478 - 146.7 1 2 0 -0.0017 11 0 0 0 7.16E+08 5.99E+08 - - - 5.7263 0.9999 221125_WJC_METTL3_EV_vs_WT_F10.04087.04087.3 0.000912 14/40 R.QIQEEEDEKQR.L "sp|O43805|SSNA1_HUMAN,tr|A0A087WV26|A0A087WV26_HUMAN" 2 1430.6638 2.5 137866 4087 3 1430.661515 477.8952 Sjoegren syndrome nuclear autoantigen 1 OS=Homo sapiens OX=9606 GN=SSNA1 PE=1 SV=2 4.25 1374.8 - 8.89E+06 - - - -1.5629 - 2.678 0.524 - 385.3 1 2 1 -0.0022 11 0 0 0 2.70E+08 1.08E+08 - - - 7.1799 0.9993 221125_WJC_METTL3_EV_vs_WT_F10.04088.04088.3 0.00312 15/36 R.RGLDDDRGPR.R sp|Q14152|EIF3A_HUMAN 1 1155.5745 1.13 137867 4088 3 1155.57246 386.1988 Eukaryotic translation initiation factor 3 subunit A OS=Homo sapiens OX=9606 GN=EIF3A PE=1 SV=1 6.04 1374.9 - 2.84E+06 - - - -1.7498 - 2.437 0.365 - 410.1 1 2 1 -0.002 10 0 0 0 9.45E+07 8.35E+07 - - - 5.2103 0.9997 221125_WJC_METTL3_EV_vs_WT_F10.04089.04089.3 0.119 Nov-40 K.LGIHEDSQNR[166.11]K[136.11].K sp|P07900|HS90A_HUMAN 1 1313.6807 0.87 137868 4089 3 1313.681247 438.9008 Heat shock protein HSP 90-alpha OS=Homo sapiens OX=9606 GN=HSP90AA1 PE=1 SV=5 6.75 1374.9 - 2.26E+06 - - - 0.4301 - 2.132 0.32 - 153.5 1 2 0 0.0006 11 0 0 0 2.24E+07 2.59E+07 - - - 4.2582 0.9042 221125_WJC_METTL3_EV_vs_WT_F10.04090.04090.3 0.153 Oct-44 K.ELK[136.11]TDSSPNQAR[166.11].A "sp|P26599|PTBP1_HUMAN,tr|A0A6Q8PEX4|A0A6Q8PEX4_HUMAN,tr|A6NLN1|A6NLN1_HUMAN,tr|A0A087WU68|A0A087WU68_HUMAN,tr|K7ES59|K7ES59_HUMAN,tr|A0A7I2V4H6|A0A7I2V4H6_HUMAN,tr|A0A7I2V621|A0A7I2V621_HUMAN" 7 1362.6858 1.43 137869 4090 3 1362.685083 455.2359 Polypyrimidine tract-binding protein 1 OS=Homo sapiens OX=9606 GN=PTBP1 PE=1 SV=1 6.17 1375 - 1.74E+06 - - - -0.546 - 1.76 0.109 - 219.8 1 2 1 -0.0007 12 0 0 0 6.64E+07 4.64E+07 - - - 1.322 0.9999 221125_WJC_METTL3_EV_vs_WT_F10.04091.04091.3 0.000212 Oct-40 K.LGIHEDSQNRK.K sp|P07900|HS90A_HUMAN 1 1295.6582 0.71 137870 4091 3 1295.659028 432.8933 Heat shock protein HSP 90-alpha OS=Homo sapiens OX=9606 GN=HSP90AA1 PE=1 SV=5 6.75 1375.1 - 1.21E+06 - - - 0.6298 - 1.994 0.407 - 126 1 2 0 0.0008 11 0 0 0 1.82E+07 2.58E+07 - - - 5.038 0.9999 221125_WJC_METTL3_EV_vs_WT_F10.04093.04093.3 0.00171 13/48 K.SQQVAAAAHEANK[136.11].L "sp|Q12830|BPTF_HUMAN,tr|F5GXF5|F5GXF5_HUMAN,tr|E9PE19|E9PE19_HUMAN,tr|E7ETD6|E7ETD6_HUMAN,tr|A0A2R8Y7Q1|A0A2R8Y7Q1_HUMAN,tr|A0A0A0MR81|A0A0A0MR81_HUMAN" 6 1331.6673 30.9 137872 4093 3 1331.66733 444.8964 Nucleosome-remodeling factor subunit BPTF OS=Homo sapiens OX=9606 GN=BPTF PE=1 SV=3 6.47 1375.3 - 586852 - - - 0.0023 - 2.338 0.407 - 121.3 1 2 0 0 13 0 0 0 3.41E+08 1.10E+07 - - - 5.3803 0.9998 221125_WJC_METTL3_EV_vs_WT_F10.04097.04097.2 1.29E-05 18-Sep K.HTANYDTEER.V "sp|Q99590|SCAFB_HUMAN,tr|F8VXG7|F8VXG7_HUMAN,tr|A0A0A0MTP7|A0A0A0MTP7_HUMAN" 3 1234.5214 1.27 137874 4097 2 1234.519725 618.268 Protein SCAF11 OS=Homo sapiens OX=9606 GN=SCAF11 PE=1 SV=2 4.65 1375.9 - 406684 - - - -1.3924 - 1.781 0.578 - 203.3 1 2 0 -0.0017 10 0 0 0 4.28E+06 3.37E+06 - - - 4.9206 0.9975 221125_WJC_METTL3_EV_vs_WT_F10.04099.04099.2 1.80E-05 13/20 R.QIQEEEDEKQR.L "sp|O43805|SSNA1_HUMAN,tr|A0A087WV26|A0A087WV26_HUMAN" 2 1430.6638 2.94 137875 4099 2 1430.660629 716.3392 Sjoegren syndrome nuclear autoantigen 1 OS=Homo sapiens OX=9606 GN=SSNA1 PE=1 SV=2 4.25 1376.1 - 1.25E+06 - - - -2.1822 - 2.456 0.533 - 801.8 1 2 1 -0.0031 11 0 0 0 1.51E+07 5.13E+06 - - - 5.4075 0.998 221125_WJC_METTL3_EV_vs_WT_F10.04100.04100.2 0.000459 20-Dec R.QIQEEEDEK[136.11]QR[166.11].L "sp|O43805|SSNA1_HUMAN,tr|A0A087WV26|A0A087WV26_HUMAN" 2 1448.6862 2.94 137876 4100 2 1448.68437 725.3504 Sjoegren syndrome nuclear autoantigen 1 OS=Homo sapiens OX=9606 GN=SSNA1 PE=1 SV=2 4.25 1376.2 - 290435 - - - -1.2777 - 2.088 0.505 - 412.9 1 2 1 -0.0019 11 0 0 0 1.51E+07 5.13E+06 - - - 4.762 0.9302 221125_WJC_METTL3_EV_vs_WT_F10.04108.04108.2 0.0303 20-Sep L.THSTTEVTQPR[166.11].T "sp|P78347|GTF2I_HUMAN,tr|A0A494C0Q7|A0A494C0Q7_HUMAN,tr|A0A494C1K3|A0A494C1K3_HUMAN" 3 1265.6239 1.91 137882 4108 2 1265.625786 633.8193 General transcription factor II-I OS=Homo sapiens OX=9606 GN=GTF2I PE=1 SV=2 6.41 1377.1 - 118064 - - - 1.4515 - 1.541 0.328 - 277.4 1 1 0 0.0018 11 0 0 0 4.30E+06 2.25E+06 - - - 2.6329 0.9984 221125_WJC_METTL3_EV_vs_WT_F10.04109.04109.2 0.0437 16-Sep K.KHELLNSTR.E "sp|P78347|GTF2I_HUMAN,tr|A0A494C0Q7|A0A494C0Q7_HUMAN,tr|A0A494C1K3|A0A494C1K3_HUMAN" 3 1096.5989 1.35 137883 4109 2 1096.59702 549.3067 General transcription factor II-I OS=Homo sapiens OX=9606 GN=GTF2I PE=1 SV=2 8.75 1377.2 - 293027 - - - -1.7199 - 1.489 0.307 - 320.3 1 2 0 -0.0019 9 0 0 0 6.63E+07 4.90E+07 - - - 2.4596 0.9997 221125_WJC_METTL3_EV_vs_WT_F10.04111.04111.3 2.39E-06 15/40 R.QIQEEEDEK[136.11]QR[166.11].L "sp|O43805|SSNA1_HUMAN,tr|A0A087WV26|A0A087WV26_HUMAN" 2 1448.6862 2.5 137884 4111 3 1448.683121 483.9027 Sjoegren syndrome nuclear autoantigen 1 OS=Homo sapiens OX=9606 GN=SSNA1 PE=1 SV=2 4.25 1377.4 - 8.10E+06 - - - -2.1399 - 2.778 0.437 - 463 1 2 1 -0.0031 11 0 0 0 2.70E+08 1.08E+08 - - - 6.3138 0.9998 221125_WJC_METTL3_EV_vs_WT_F10.04114.04114.2 0.00142 14/16 K.K[136.11]YHNVGLSK[136.11].C "sp|Q14103|HNRPD_HUMAN,tr|H0Y8G5|H0Y8G5_HUMAN,tr|H0YA96|H0YA96_HUMAN" 3 1060.6 1.13 137886 4114 2 1060.598114 531.3073 Heterogeneous nuclear ribonucleoprotein D0 OS=Homo sapiens OX=9606 GN=HNRNPD PE=1 SV=1 9.7 1377.7 - 1.57E+06 - - - -1.8056 - 2.451 0.439 - 755.3 1 2 0 -0.0019 9 0 0 0 2.51E+07 2.23E+07 - - - 4.8765 0.9939 221125_WJC_METTL3_EV_vs_WT_F10.04116.04116.2 1.78E-05 22-Dec K.ELK[136.11]TDSSPNQAR[166.11].A "sp|P26599|PTBP1_HUMAN,tr|A0A6Q8PEX4|A0A6Q8PEX4_HUMAN,tr|A6NLN1|A6NLN1_HUMAN,tr|A0A087WU68|A0A087WU68_HUMAN,tr|K7ES59|K7ES59_HUMAN,tr|A0A7I2V4H6|A0A7I2V4H6_HUMAN,tr|A0A7I2V621|A0A7I2V621_HUMAN" 7 1362.6858 1.69 137888 4116 2 1362.681975 682.3502 Polypyrimidine tract-binding protein 1 OS=Homo sapiens OX=9606 GN=PTBP1 PE=1 SV=1 6.17 1378 - 178810 - - - -2.8268 - 1.894 0.528 - 390 1 2 1 -0.0039 12 0 0 0 4.09E+06 2.42E+06 - - - 4.6201 0.9999 221125_WJC_METTL3_EV_vs_WT_F10.04120.04120.3 0.000184 13/36 R.R[166.11]GLDDDR[166.11]GPR[166.11].R sp|Q14152|EIF3A_HUMAN 1 1185.5993 1.13 137890 4120 3 1185.598006 396.207 Eukaryotic translation initiation factor 3 subunit A OS=Homo sapiens OX=9606 GN=EIF3A PE=1 SV=1 6.04 1378.5 - 4.17E+06 - - - -1.0847 - 2.415 0.479 - 266.6 1 2 1 -0.0013 10 0 0 0 9.45E+07 8.35E+07 - - - 6.455 0.9993 221125_WJC_METTL3_EV_vs_WT_F10.04128.04128.3 0.00452 Nov-36 K.QQK[136.11]PTLSGQR[166.11].F "sp|Q7L1Q6|BZW1_HUMAN,tr|C9JFN4|C9JFN4_HUMAN,tr|C9JV57|C9JV57_HUMAN,tr|C9JWF5|C9JWF5_HUMAN,tr|C9J188|C9J188_HUMAN,tr|C9IZ80|C9IZ80_HUMAN" 6 1159.6428 0.7 137896 4128 3 1159.640842 387.5549 Basic leucine zipper and W2 domain-containing protein 1 OS=Homo sapiens OX=9606 GN=BZW1 PE=1 SV=1 11 1379.3 - 6.26E+06 - - - -1.7229 - 1.873 0.312 - 191.1 1 2 0 -0.002 10 0 0 0 4.54E+07 6.51E+07 - - - 3.8506 0.9998 221125_WJC_METTL3_EV_vs_WT_F10.04129.04129.3 5.00E-05 13/48 R.INSTATPDQDR[166.11]DK[136.11].L sp|Q9H2G2|SLK_HUMAN 1 1477.7128 0.84 137897 4129 3 1477.710457 493.5782 STE20-like serine\threonine-protein kinase OS=Homo sapiens OX=9606 GN=SLK PE=1 SV=1 4.43 1379.4 - 1.58E+06 - - - -1.5653 - 2.524 0.478 - 224.5 1 2 1 -0.0023 13 0 0 0 2.16E+07 2.58E+07 - - - 6.3788 0.9999 221125_WJC_METTL3_EV_vs_WT_F10.04132.04132.3 9.54E-05 Nov-44 K.GC[160.03]SEDHSGLDAK[136.11].S sp|Q5JSZ5|PRC2B_HUMAN 1 1282.5339 1.41 137900 4132 3 1282.532031 428.5186 Protein PRRC2B OS=Homo sapiens OX=9606 GN=PRRC2B PE=1 SV=2 4.54 1379.6 - 988013 - - - -1.4807 - 1.606 0.486 - 164.9 1 2 0 -0.0019 12 0 0 0 4.32E+07 3.06E+07 - - - 5.271 0.9994 221125_WJC_METTL3_EV_vs_WT_F10.04133.04133.2 0.0015 18-Aug K.QQK[136.11]PTLSGQR[166.11].F "sp|Q7L1Q6|BZW1_HUMAN,tr|C9JFN4|C9JFN4_HUMAN,tr|C9JV57|C9JV57_HUMAN,tr|C9JWF5|C9JWF5_HUMAN,tr|C9J188|C9J188_HUMAN,tr|C9IZ80|C9IZ80_HUMAN" 6 1159.6428 0.73 137901 4133 2 1159.642864 580.8287 Basic leucine zipper and W2 domain-containing protein 1 OS=Homo sapiens OX=9606 GN=BZW1 PE=1 SV=1 11 1379.7 - 437585 - - - 0.0207 - 1.491 0.365 - 170.4 1 2 0 0 10 0 0 0 4.33E+06 5.89E+06 - - - 2.8519 0.9989 221125_WJC_METTL3_EV_vs_WT_F10.04136.04136.2 0.00303 20-Sep K.ISR[166.11]PGDSDDSR[166.11].S "sp|P14866|HNRPL_HUMAN,tr|M0QYL7|M0QYL7_HUMAN,tr|B4DVF8|B4DVF8_HUMAN,tr|M0R1W6|M0R1W6_HUMAN,tr|A0A3B3ITJ4|A0A3B3ITJ4_HUMAN,tr|M0QXS5|M0QXS5_HUMAN" 6 1223.5645 1.35 137903 4136 2 1223.562327 612.7895 Heterogeneous nuclear ribonucleoprotein L OS=Homo sapiens OX=9606 GN=HNRNPL PE=1 SV=2 4.43 1380.1 - 796789 - - - -1.8029 - 1.578 0.349 - 122.3 1 2 0 -0.0022 11 0 0 0 9.86E+07 7.30E+07 - - - 2.852 0.9995 221125_WJC_METTL3_EV_vs_WT_F10.04140.04140.2 0.121 16-Oct K.KYHNVGLSK.C "sp|Q14103|HNRPD_HUMAN,tr|H0Y8G5|H0Y8G5_HUMAN,tr|H0YA96|H0YA96_HUMAN" 3 1044.5716 1.12 137906 4140 2 1044.569916 523.2931 Heterogeneous nuclear ribonucleoprotein D0 OS=Homo sapiens OX=9606 GN=HNRNPD PE=1 SV=1 9.7 1380.6 - 1.05E+06 - - - -1.6399 - 1.829 0.387 - 311.5 1 2 0 -0.0017 9 0 0 0 2.50E+07 2.23E+07 - - - 3.6456 0.9994 221125_WJC_METTL3_EV_vs_WT_F10.04143.04143.2 0.0391 16-Nov K.K[136.11]HELLNSTR[166.11].E "sp|P78347|GTF2I_HUMAN,tr|A0A494C0Q7|A0A494C0Q7_HUMAN,tr|A0A494C1K3|A0A494C1K3_HUMAN" 3 1114.6214 1.35 137907 4143 2 1114.61965 558.318 General transcription factor II-I OS=Homo sapiens OX=9606 GN=GTF2I PE=1 SV=2 8.75 1381 - 4.82E+06 - - - -1.5485 - 1.762 0.352 - 488.4 1 2 0 -0.0017 9 0 0 0 6.63E+07 4.90E+07 - - - 3.2791 0.9928 221125_WJC_METTL3_EV_vs_WT_F10.04151.04151.3 1.13E-06 Dec-52 Q.KEESAASGGAAYTK.R "sp|Q9Y2W1|TR150_HUMAN,tr|A0A3B3ITZ9|A0A3B3ITZ9_HUMAN" 2 1368.6521 0.3 137913 4151 3 1368.649013 457.2247 Thyroid hormone receptor-associated protein 3 OS=Homo sapiens OX=9606 GN=THRAP3 PE=1 SV=2 6.14 1381.9 - 4.85E+06 - - - -2.273 - 2.391 0.501 - 187.6 1 1 0 -0.0031 14 0 0 0 4.14E+07 1.40E+08 - - - 6.4414 0.959 221125_WJC_METTL3_EV_vs_WT_F10.04152.04152.3 0.0669 Nov-36 K.QQKPTLSGQR.F "sp|Q7L1Q6|BZW1_HUMAN,tr|C9JFN4|C9JFN4_HUMAN,tr|C9JV57|C9JV57_HUMAN,tr|C9JWF5|C9JWF5_HUMAN,tr|C9J188|C9J188_HUMAN,tr|C9IZ80|C9IZ80_HUMAN" 6 1141.6204 0.7 137914 4152 3 1141.617921 381.5474 Basic leucine zipper and W2 domain-containing protein 1 OS=Homo sapiens OX=9606 GN=BZW1 PE=1 SV=1 11 1382 - 2.55E+06 - - - -2.1452 - 1.743 0.108 - 180.6 1 2 0 -0.0024 10 0 0 0 4.54E+07 6.51E+07 - - - 1.366 0.9994 221125_WJC_METTL3_EV_vs_WT_F10.04156.04156.3 0.000983 Nov-44 R.SVDSSGETTYK[136.11]K[136.11].T "sp|Q99755|PI51A_HUMAN,tr|A2A5X0|A2A5X0_HUMAN,tr|A6PW57|A6PW57_HUMAN,tr|A6PW58|A6PW58_HUMAN" 4 1316.6431 0.52 137918 4156 3 1316.638173 439.8883 Phosphatidylinositol 4-phosphate 5-kinase type-1 alpha OS=Homo sapiens OX=9606 GN=PIP5K1A PE=1 SV=1 5.79 1382.2 - 1.82E+06 - - - -3.7239 - 2.004 0.436 - 86.2 1 2 0 -0.0049 12 0 0 0 6.81E+06 1.30E+07 - - - 5.3264 0.9997 221125_WJC_METTL3_EV_vs_WT_F10.04157.04157.3 0.0443 Dec-44 R.LQK[136.11]PTDSTASSR[166.11].A "sp|Q9UPT8|ZC3H4_HUMAN,tr|M0QY97|M0QY97_HUMAN" 2 1307.68 1.71 137919 4157 3 1307.67668 436.9006 Zinc finger CCCH domain-containing protein 4 OS=Homo sapiens OX=9606 GN=ZC3H4 PE=1 SV=3 8.75 1382.3 - 920344 - - - -2.5488 - 2.446 0.368 - 246.8 1 2 0 -0.0033 12 0 0 0 2.08E+07 1.22E+07 - - - 5.1212 1 221125_WJC_METTL3_EV_vs_WT_F10.04159.04159.2 5.00E-09 22-Dec K.GC[160.03]SEDHSGLDAK[136.11].S sp|Q5JSZ5|PRC2B_HUMAN 1 1282.5339 1.57 137921 4159 2 1282.531702 642.2742 Protein PRRC2B OS=Homo sapiens OX=9606 GN=PRRC2B PE=1 SV=2 4.54 1382.6 - 414836 - - - -1.7372 - 2.353 0.7 - 440.6 1 2 0 -0.0022 12 0 0 0 4.74E+06 3.03E+06 - - - 6.462 0.9999 221125_WJC_METTL3_EV_vs_WT_F10.04165.04165.3 1.06E-05 13/52 K.SMTSAHGSASVNSR.W "sp|Q5SW79|CE170_HUMAN,tr|H0Y2V6|H0Y2V6_HUMAN" 2 1390.6259 1.29 137924 4165 3 1390.621522 464.5493 Centrosomal protein of 170 kDa OS=Homo sapiens OX=9606 GN=CEP170 PE=1 SV=1 9.49 1383.3 - 1.27E+06 - - - -3.1669 - 2.437 0.53 - 187.1 1 2 0 -0.0044 14 0 0 0 1.27E+07 9.86E+06 - - - 6.815 0.9997 221125_WJC_METTL3_EV_vs_WT_F10.04167.04167.3 9.45E-06 Dec-40 R.YRSDSQDEVEK.G "sp|Q15390|MTFR1_HUMAN,tr|H0YBZ4|H0YBZ4_HUMAN,tr|H7C5V5|H7C5V5_HUMAN,tr|H0YF01|H0YF01_HUMAN" 4 1354.6001 2.54 137926 4167 3 1354.597486 452.5406 Mitochondrial fission regulator 1 OS=Homo sapiens OX=9606 GN=MTFR1 PE=1 SV=2 4.32 1383.4 - 1.56E+06 - - - -1.9209 - 2.292 0.478 - 313.1 1 2 1 -0.0026 11 0 0 0 1.24E+07 4.88E+06 - - - 6.2248 0.9162 221125_WJC_METTL3_EV_vs_WT_F10.04168.04168.3 0.066 Nov-48 K.EESEKEQTAVETK.K "sp|Q9UHC7|MKRN1_HUMAN,tr|C9IY57|C9IY57_HUMAN,tr|C9J031|C9J031_HUMAN" 3 1506.7049 7.62 137927 4168 3 1506.701521 503.2423 E3 ubiquitin-protein ligase makorin-1 OS=Homo sapiens OX=9606 GN=MKRN1 PE=1 SV=3 4.33 1383.6 - 713608 - - - -2.2738 - 1.164 0.262 - 106.7 1 2 1 -0.0034 13 0 0 0 1.69E+07 2.21E+06 - - - 1.8718 0.9998 221125_WJC_METTL3_EV_vs_WT_F10.04169.04169.3 7.95E-06 14/56 K.VSKQEEASGGPTAPK.A "sp|P50552|VASP_HUMAN,tr|K7EM16|K7EM16_HUMAN" 2 1484.7471 1.84 137928 4169 3 1484.744983 495.923 Vasodilator-stimulated phosphoprotein OS=Homo sapiens OX=9606 GN=VASP PE=1 SV=3 6.11 1383.7 - 494999 - - - -1.4171 - 2.376 0.518 - 244.5 1 2 1 -0.0021 15 0 0 0 6.15E+06 3.34E+06 - - - 6.5728 0.9986 221125_WJC_METTL3_EV_vs_WT_F10.04174.04174.2 0.247 20-Dec K.VAEIEHAEK[136.11]EK[136.11].M "sp|P78371|TCPB_HUMAN,tr|F8VQ14|F8VQ14_HUMAN,tr|F5GWF6|F5GWF6_HUMAN" 3 1297.6849 0.47 137933 4174 2 1297.684121 649.8497 T-complex protein 1 subunit beta OS=Homo sapiens OX=9606 GN=CCT2 PE=1 SV=4 4.91 1384.3 - 143961 - - - -0.5857 - 2.59 0.441 - 528.2 1 2 1 -0.0008 11 0 0 0 1.77E+07 3.73E+07 - - - 4.8724 0.9999 221125_WJC_METTL3_EV_vs_WT_F10.04177.04177.3 2.23E-05 13/40 K.VAEIEHAEKEK.M "sp|P78371|TCPB_HUMAN,tr|F8VQ14|F8VQ14_HUMAN,tr|F5GWF6|F5GWF6_HUMAN" 3 1281.6565 0.49 137934 4177 3 1281.656061 428.2261 T-complex protein 1 subunit beta OS=Homo sapiens OX=9606 GN=CCT2 PE=1 SV=4 4.91 1384.7 - 7.87E+06 - - - -0.3277 - 2.649 0.466 - 381.8 1 2 1 -0.0004 11 0 0 0 2.31E+08 4.73E+08 - - - 6.5028 0.9999 221125_WJC_METTL3_EV_vs_WT_F10.04178.04178.3 0.017 Oct-36 R.LYEEHC[160.03]K[136.11]PER[166.11].D sp|Q13207|TBX2_HUMAN 1 1377.6466 0.87 137935 4178 3 1377.64418 460.2228 T-box transcription factor TBX2 OS=Homo sapiens OX=9606 GN=TBX2 PE=1 SV=3 5.5 1384.8 - 1.37E+06 - - - -1.7602 - 2.277 0.385 - 192.8 1 2 0 -0.0024 10 0 0 0 9.00E+06 1.03E+07 - - - 5.2348 0.9867 221125_WJC_METTL3_EV_vs_WT_F10.04180.04180.2 7.90E-05 26-Nov S.VSTSHTTISGGGSR.G sp|P04264|K2C1_HUMAN 1 1345.6586 168.37 137937 4180 2 1345.656295 673.8366 "Keratin, type II cytoskeletal 1 OS=Homo sapiens OX=9606 GN=KRT1 PE=1 SV=6" 9.73 1384.9 - 1.38E+06 - - - -1.7174 - 2.193 0.511 - 328.6 1 1 0 -0.0023 14 0 0 0 3.48E+07 2.07E+05 - - - 4.7851 0.9101 221125_WJC_METTL3_EV_vs_WT_F10.04183.04183.2 0.00228 16/18 V.AEIEHAEK[136.11]EK[136.11].M "sp|P78371|TCPB_HUMAN,tr|F8VQ14|F8VQ14_HUMAN,tr|F5GWF6|F5GWF6_HUMAN" 3 1198.6165 0.56 137940 4183 2 1198.614653 600.3155 T-complex protein 1 subunit beta OS=Homo sapiens OX=9606 GN=CCT2 PE=1 SV=4 4.91 1385.3 - 1.07E+06 - - - -1.5134 - 2.927 0.451 - 1327.9 1 1 1 -0.0018 10 0 0 0 1.25E+07 2.22E+07 - - - 5.3693 0.8236 221125_WJC_METTL3_EV_vs_WT_F10.04185.04185.3 0.00126 13/36 V.AEIEHAEKEK.M "sp|P78371|TCPB_HUMAN,tr|F8VQ14|F8VQ14_HUMAN,tr|F5GWF6|F5GWF6_HUMAN" 3 1182.5881 0.54 137942 4185 3 1182.586388 395.2033 T-complex protein 1 subunit beta OS=Homo sapiens OX=9606 GN=CCT2 PE=1 SV=4 4.91 1385.5 - 876573 - - - -1.4198 - 2.225 0.288 - 268.5 1 1 1 -0.0017 10 0 0 0 1.74E+07 3.20E+07 - - - 4.0861 0.9915 221125_WJC_METTL3_EV_vs_WT_F10.04187.04187.2 6.58E-08 24-Dec V.STSHTTISGGGSR.G sp|P04264|K2C1_HUMAN 1 1246.5902 37.22 137944 4187 2 1246.589299 624.3024 "Keratin, type II cytoskeletal 1 OS=Homo sapiens OX=9606 GN=KRT1 PE=1 SV=6" 9.49 1385.8 - 741183 - - - -0.7164 - 2.225 0.489 - 404.9 1 1 0 -0.0009 13 0 0 0 1.53E+07 4.12E+05 - - - 4.7051 1 221125_WJC_METTL3_EV_vs_WT_F10.04188.04188.2 2.23E-06 16/20 K.VAEIEHAEKEK.M "sp|P78371|TCPB_HUMAN,tr|F8VQ14|F8VQ14_HUMAN,tr|F5GWF6|F5GWF6_HUMAN" 3 1281.6565 0.47 137945 4188 2 1281.659339 641.8355 T-complex protein 1 subunit beta OS=Homo sapiens OX=9606 GN=CCT2 PE=1 SV=4 4.91 1385.9 - 422682 - - - 2.2299 - 3.049 0.56 - 1144.2 1 2 1 0.0029 11 0 0 0 1.77E+07 3.73E+07 - - - 6.1921 0.9672 221125_WJC_METTL3_EV_vs_WT_F10.04194.04194.2 0.00183 22-Dec S.TSHTTISGGGSR.G sp|P04264|K2C1_HUMAN 1 1159.5582 21.19 137951 4194 2 1159.555322 580.7864 "Keratin, type II cytoskeletal 1 OS=Homo sapiens OX=9606 GN=KRT1 PE=1 SV=6" 9.44 1386.7 - 145735 - - - -2.4509 - 1.95 0.455 - 410.4 1 1 0 -0.0028 12 0 0 0 4.44E+06 2.09E+05 - - - 4.1579 1 221125_WJC_METTL3_EV_vs_WT_F10.04208.04208.2 0.00858 16/18 V.AEIEHAEKEK.M "sp|P78371|TCPB_HUMAN,tr|F8VQ14|F8VQ14_HUMAN,tr|F5GWF6|F5GWF6_HUMAN" 3 1182.5881 0.56 137963 4208 2 1182.585678 592.3013 T-complex protein 1 subunit beta OS=Homo sapiens OX=9606 GN=CCT2 PE=1 SV=4 4.91 1387.8 - 2.70E+06 - - - -2.0201 - 2.851 0.529 - 1325.5 1 1 1 -0.0024 10 0 0 0 1.25E+07 2.22E+07 - - - 5.8718 1 221125_WJC_METTL3_EV_vs_WT_F10.04213.04213.2 2.86E-10 19/30 K.SAAQAAAQTNSNAAGK[136.11].Q sp|Q8NC51|PAIRB_HUMAN 1 1467.7157 0.82 137968 4213 2 1467.715987 734.8651 Plasminogen activator inhibitor 1 RNA-binding protein OS=Homo sapiens OX=9606 GN=SERBP1 PE=1 SV=2 8.47 1388.3 - 1.02E+06 - - - 0.1724 - 3.78 0.638 - 1346.6 1 2 0 0.0003 16 0 0 0 7.33E+08 8.90E+08 - - - 7.0224 1 221125_WJC_METTL3_EV_vs_WT_F10.04214.04214.2 2.25E-12 21/30 K.SAAQAAAQTNSNAAGK.Q sp|Q8NC51|PAIRB_HUMAN 1 1459.7015 0.82 137969 4214 2 1459.699261 730.858 Plasminogen activator inhibitor 1 RNA-binding protein OS=Homo sapiens OX=9606 GN=SERBP1 PE=1 SV=2 8.47 1388.5 - 932219 - - - -1.5572 - 3.924 0.7 - 1853.1 1 2 0 -0.0023 16 0 0 0 7.33E+08 8.90E+08 - - - 7.5716 0.9601 221125_WJC_METTL3_EV_vs_WT_F10.04215.04215.3 0.00316 Aug-40 R.IHTGEKPYEC[160.03]K.E "sp|Q32M78|ZN699_HUMAN,sp|Q3ZCX4|ZN568_HUMAN,sp|Q9H0M5|ZN700_HUMAN,sp|P58317|ZN121_HUMAN,sp|P21506|ZNF10_HUMAN,sp|Q6ZNG0|ZN620_HUMAN,sp|Q969W8|ZN566_HUMAN,sp|Q969W8|ZN566_HUMAN,sp|Q969W8|ZN566_HUMAN,sp|Q8N9K5|ZN565_HUMAN,sp|Q96SK3|ZN607_HUMAN,sp|Q6PDB4|ZN880_HUMAN,sp|Q147U1|ZN846_HUMAN,sp|Q8N141|ZFP82_HUMAN,sp|Q8N7M2|ZN283_HUMAN,sp|Q8NHY6|ZFP28_HUMAN,sp|Q9BUY5|ZN426_HUMAN,sp|O75290|Z780A_HUMAN,sp|Q9NQX6|ZN331_HUMAN,sp|Q7Z3V5|ZN571_HUMAN,sp|Q14585|ZN345_HUMAN,sp|Q14585|ZN345_HUMAN,sp|Q14585|ZN345_HUMAN,sp|Q494X3|ZN404_HUMAN,sp|Q9H7R0|ZN442_HUMAN,sp|Q96ND8|ZN583_HUMAN,sp|Q8TAQ5|ZN420_HUMAN,sp|A8MQ14|ZN850_HUMAN,sp|Q96NG8|ZN582_HUMAN,sp|Q9BX82|ZN471_HUMAN,sp|Q96MU6|ZN778_HUMAN,sp|Q8N2I2|ZN619_HUMAN,sp|Q9UJL9|ZF69B_HUMAN,sp|Q6P280|ZN529_HUMAN,sp|Q9Y2G7|ZFP30_HUMAN,sp|Q9Y2G7|ZFP30_HUMAN,sp|Q9Y2G7|ZFP30_HUMAN,sp|Q9HCL3|ZFP14_HUMAN,sp|Q9HCL3|ZFP14_HUMAN,sp|Q9HCL3|ZFP14_HUMAN,sp|P17039|ZNF30_HUMAN,sp|P17039|ZNF30_HUMAN,sp|Q8NDP4|ZN439_HUMAN,sp|Q8N972|ZN709_HUMAN,sp|Q96LW9|ZSC31_HUMAN,sp|Q8TAF7|ZN461_HUMAN,sp|Q8TAF7|ZN461_HUMAN,sp|Q8TAF7|ZN461_HUMAN,sp|Q8NEP9|ZN555_HUMAN,sp|Q3KNS6|ZN829_HUMAN,sp|Q3KNS6|ZN829_HUMAN,sp|Q9Y6R6|Z780B_HUMAN,sp|Q8TA94|ZN563_HUMAN,sp|Q3KP31|ZN791_HUMAN,sp|Q9UC07|ZNF69_HUMAN,sp|Q8N9F8|ZN454_HUMAN,sp|Q3ZCT1|ZN260_HUMAN,sp|Q8NDQ6|ZN540_HUMAN,sp|Q8NDQ6|ZN540_HUMAN,sp|Q8NDQ6|ZN540_HUMAN,sp|C9JN71|ZN878_HUMAN,sp|Q9ULM2|ZN490_HUMAN,sp|P15621|ZNF44_HUMAN,sp|Q6PG37|ZN790_HUMAN,sp|Q8N587|ZN561_HUMAN,sp|Q86UE3|ZN546_HUMAN,sp|Q96NI8|ZN570_HUMAN,sp|Q6ZSS3|ZN621_HUMAN,sp|Q7Z7L9|ZSCA2_HUMAN,sp|Q6ECI4|ZN470_HUMAN,sp|Q8NB42|ZN527_HUMAN,sp|Q8NA42|ZN383_HUMAN,sp|Q96BR6|ZN669_HUMAN,tr|B4DRP8|B4DRP8_HUMAN,tr|B4DRP8|B4DRP8_HUMAN,tr|B4DRP8|B4DRP8_HUMAN,tr|A0A0C4DFQ3|A0A0C4DFQ3_HUMAN,tr|A0A0C4DFR4|A0A0C4DFR4_HUMAN,tr|A0A1W2PPI4|A0A1W2PPI4_HUMAN,tr|K7EP39|K7EP39_HUMAN,tr|A0A0C4DGP9|A0A0C4DGP9_HUMAN,tr|E7ETJ5|E7ETJ5_HUMAN,tr|F8WD46|F8WD46_HUMAN,tr|A0A0C4DG37|A0A0C4DG37_HUMAN,tr|A0A0C4DG08|A0A0C4DG08_HUMAN,tr|C9JZC2|C9JZC2_HUMAN,tr|C9JTJ1|C9JTJ1_HUMAN,tr|F8W6Y9|F8W6Y9_HUMAN,tr|K7EQC1|K7EQC1_HUMAN,tr|F8W8R5|F8W8R5_HUMAN,tr|K7ER43|K7ER43_HUMAN,tr|K7ESJ1|K7ESJ1_HUMAN,tr|A8KAD9|A8KAD9_HUMAN,tr|A0A0A0MSW5|A0A0A0MSW5_HUMAN,tr|A0A087WV02|A0A087WV02_HUMAN,tr|A0A087WV02|A0A087WV02_HUMAN,tr|A0A087WV02|A0A087WV02_HUMAN,tr|A0A087WWI3|A0A087WWI3_HUMAN,tr|A0A494C0U8|A0A494C0U8_HUMAN,tr|A0A087WSV7|A0A087WSV7_HUMAN,tr|M0QY24|M0QY24_HUMAN,tr|A0A087WVP9|A0A087WVP9_HUMAN,tr|A0A087WVP9|A0A087WVP9_HUMAN,tr|A0A087WVP9|A0A087WVP9_HUMAN,tr|K7EKZ8|K7EKZ8_HUMAN,tr|F8W7T7|F8W7T7_HUMAN,tr|A0A804HI69|A0A804HI69_HUMAN,tr|C9J423|C9J423_HUMAN,tr|A0A087X0M6|A0A087X0M6_HUMAN,tr|K7EQV7|K7EQV7_HUMAN,tr|K7EM63|K7EM63_HUMAN,tr|A0A087WVH9|A0A087WVH9_HUMAN,tr|K7EK80|K7EK80_HUMAN,tr|Q17RW3|Q17RW3_HUMAN,tr|B4DRR6|B4DRR6_HUMAN,tr|B4DRR6|B4DRR6_HUMAN,tr|B4DRR6|B4DRR6_HUMAN" 117 1360.6445 0.94 137970 4215 3 1360.638519 454.5555 Zinc finger protein 699 OS=Homo sapiens OX=9606 GN=ZNF699 PE=1 SV=1 6.75 1388.5 - 917481 - - - -4.4222 - 1.744 0.204 - 85.4 1 2 0 -0.006 11 0 0 0 5.83E+06 6.21E+06 - - - 2.3927 1 221125_WJC_METTL3_EV_vs_WT_F10.04221.04221.3 8.54E-08 17/60 K.SAAQAAAQTNSNAAGK.Q sp|Q8NC51|PAIRB_HUMAN 1 1459.7015 0.91 137974 4221 3 1459.698912 487.5745 Plasminogen activator inhibitor 1 RNA-binding protein OS=Homo sapiens OX=9606 GN=SERBP1 PE=1 SV=2 8.47 1389.3 - 1.41E+07 - - - -1.7963 - 3.118 0.574 - 432.7 1 2 0 -0.0026 16 0 0 0 3.99E+08 4.39E+08 - - - 7.8567 0.9998 221125_WJC_METTL3_EV_vs_WT_F10.04222.04222.3 4.54E-05 19/40 K.R[166.11]R[166.11]DDGLSAAAR[166.11].K "sp|P84101|SERF2_HUMAN,tr|B8ZZY7|B8ZZY7_HUMAN,tr|F8WBV6|F8WBV6_HUMAN,tr|F8WBN3|F8WBN3_HUMAN,tr|B9A031|B9A031_HUMAN,tr|C9JQZ0|C9JQZ0_HUMAN" 6 1216.6415 0.82 137975 4222 3 1216.638423 406.5544 Small EDRK-rich factor 2 OS=Homo sapiens OX=9606 GN=SERF2 PE=1 SV=1 9.51 1389.4 - 5.03E+06 - - - -2.5225 - 3.072 0.51 - 683.2 1 2 1 -0.0031 11 0 0 0 2.38E+07 2.90E+07 - - - 7.4135 0.9978 221125_WJC_METTL3_EV_vs_WT_F10.04223.04223.3 0.041 14/36 K.DR[166.11]HEASGFAR[166.11].R "sp|Q96I25|SPF45_HUMAN,tr|Q5W012|Q5W012_HUMAN,tr|Q5W010|Q5W010_HUMAN,tr|Q5W011|Q5W011_HUMAN,tr|H0Y6J6|H0Y6J6_HUMAN" 5 1164.5539 0.93 137976 4223 3 1164.550774 389.1919 Splicing factor 45 OS=Homo sapiens OX=9606 GN=RBM17 PE=1 SV=1 6.75 1389.4 - 2.49E+06 - - - -2.692 - 2.532 0.315 - 540.9 1 2 1 -0.0031 10 0 0 0 1.51E+07 1.63E+07 - - - 4.7642 0.9998 221125_WJC_METTL3_EV_vs_WT_F10.04225.04225.3 6.91E-05 16/52 R.STPAEDDSR[166.11]DSQVK[136.11].S "sp|Q9UHB6|LIMA1_HUMAN,tr|F8VRN8|F8VRN8_HUMAN,tr|F8VQE1|F8VQE1_HUMAN,tr|F8VS07|F8VS07_HUMAN" 4 1551.7132 1.25 137978 4225 3 1551.710142 518.245 LIM domain and actin-binding protein 1 OS=Homo sapiens OX=9606 GN=LIMA1 PE=1 SV=1 4.23 1389.6 - 1.75E+06 - - - -1.9475 - 3.025 0.466 - 410.3 1 2 1 -0.003 14 0 0 0 8.41E+06 6.71E+06 - - - 6.6763 0.9999 221125_WJC_METTL3_EV_vs_WT_F10.04226.04226.3 0.000173 Aug-40 R.QGSYHEQSVDR.S "sp|P20930|FILA_HUMAN,sp|P20930|FILA_HUMAN" 2 1304.5745 4.91 137979 4226 3 1304.571847 435.8655 Filaggrin OS=Homo sapiens OX=9606 GN=FLG PE=1 SV=3 5.32 1389.7 - 2.60E+06 - - - -2.0658 - 1.93 0.466 - 96.8 1 2 0 -0.0027 11 0 0 0 7.39E+06 1.51E+06 - - - 5.6026 0.896 221125_WJC_METTL3_EV_vs_WT_F10.04227.04227.3 5.53 Oct-40 R.IHTGEK[136.11]PYEC[160.03]K[136.11].E "sp|Q32M78|ZN699_HUMAN,sp|Q3ZCX4|ZN568_HUMAN,sp|Q9H0M5|ZN700_HUMAN,sp|P58317|ZN121_HUMAN,sp|P21506|ZNF10_HUMAN,sp|Q6ZNG0|ZN620_HUMAN,sp|Q969W8|ZN566_HUMAN,sp|Q969W8|ZN566_HUMAN,sp|Q969W8|ZN566_HUMAN,sp|Q8N9K5|ZN565_HUMAN,sp|Q96SK3|ZN607_HUMAN,sp|Q6PDB4|ZN880_HUMAN,sp|Q147U1|ZN846_HUMAN,sp|Q8N141|ZFP82_HUMAN,sp|Q8N7M2|ZN283_HUMAN,sp|Q8NHY6|ZFP28_HUMAN,sp|Q9BUY5|ZN426_HUMAN,sp|O75290|Z780A_HUMAN,sp|Q9NQX6|ZN331_HUMAN,sp|Q7Z3V5|ZN571_HUMAN,sp|Q14585|ZN345_HUMAN,sp|Q14585|ZN345_HUMAN,sp|Q14585|ZN345_HUMAN,sp|Q494X3|ZN404_HUMAN,sp|Q9H7R0|ZN442_HUMAN,sp|Q96ND8|ZN583_HUMAN,sp|Q8TAQ5|ZN420_HUMAN,sp|A8MQ14|ZN850_HUMAN,sp|Q96NG8|ZN582_HUMAN,sp|Q9BX82|ZN471_HUMAN,sp|Q96MU6|ZN778_HUMAN,sp|Q8N2I2|ZN619_HUMAN,sp|Q9UJL9|ZF69B_HUMAN,sp|Q6P280|ZN529_HUMAN,sp|Q9Y2G7|ZFP30_HUMAN,sp|Q9Y2G7|ZFP30_HUMAN,sp|Q9Y2G7|ZFP30_HUMAN,sp|Q9HCL3|ZFP14_HUMAN,sp|Q9HCL3|ZFP14_HUMAN,sp|Q9HCL3|ZFP14_HUMAN,sp|P17039|ZNF30_HUMAN,sp|P17039|ZNF30_HUMAN,sp|Q8NDP4|ZN439_HUMAN,sp|Q8N972|ZN709_HUMAN,sp|Q96LW9|ZSC31_HUMAN,sp|Q8TAF7|ZN461_HUMAN,sp|Q8TAF7|ZN461_HUMAN,sp|Q8TAF7|ZN461_HUMAN,sp|Q8NEP9|ZN555_HUMAN,sp|Q3KNS6|ZN829_HUMAN,sp|Q3KNS6|ZN829_HUMAN,sp|Q9Y6R6|Z780B_HUMAN,sp|Q8TA94|ZN563_HUMAN,sp|Q3KP31|ZN791_HUMAN,sp|Q9UC07|ZNF69_HUMAN,sp|Q8N9F8|ZN454_HUMAN,sp|Q3ZCT1|ZN260_HUMAN,sp|Q8NDQ6|ZN540_HUMAN,sp|Q8NDQ6|ZN540_HUMAN,sp|Q8NDQ6|ZN540_HUMAN,sp|C9JN71|ZN878_HUMAN,sp|Q9ULM2|ZN490_HUMAN,sp|P15621|ZNF44_HUMAN,sp|Q6PG37|ZN790_HUMAN,sp|Q8N587|ZN561_HUMAN,sp|Q86UE3|ZN546_HUMAN,sp|Q96NI8|ZN570_HUMAN,sp|Q6ZSS3|ZN621_HUMAN,sp|Q7Z7L9|ZSCA2_HUMAN,sp|Q6ECI4|ZN470_HUMAN,sp|Q8NB42|ZN527_HUMAN,sp|Q8NA42|ZN383_HUMAN,sp|Q96BR6|ZN669_HUMAN,tr|B4DRP8|B4DRP8_HUMAN,tr|B4DRP8|B4DRP8_HUMAN,tr|B4DRP8|B4DRP8_HUMAN,tr|A0A0C4DFQ3|A0A0C4DFQ3_HUMAN,tr|A0A0C4DFR4|A0A0C4DFR4_HUMAN,tr|A0A1W2PPI4|A0A1W2PPI4_HUMAN,tr|K7EP39|K7EP39_HUMAN,tr|A0A0C4DGP9|A0A0C4DGP9_HUMAN,tr|E7ETJ5|E7ETJ5_HUMAN,tr|F8WD46|F8WD46_HUMAN,tr|A0A0C4DG37|A0A0C4DG37_HUMAN,tr|A0A0C4DG08|A0A0C4DG08_HUMAN,tr|C9JZC2|C9JZC2_HUMAN,tr|C9JTJ1|C9JTJ1_HUMAN,tr|F8W6Y9|F8W6Y9_HUMAN,tr|K7EQC1|K7EQC1_HUMAN,tr|F8W8R5|F8W8R5_HUMAN,tr|K7ER43|K7ER43_HUMAN,tr|K7ESJ1|K7ESJ1_HUMAN,tr|A8KAD9|A8KAD9_HUMAN,tr|A0A0A0MSW5|A0A0A0MSW5_HUMAN,tr|A0A087WV02|A0A087WV02_HUMAN,tr|A0A087WV02|A0A087WV02_HUMAN,tr|A0A087WV02|A0A087WV02_HUMAN,tr|A0A087WWI3|A0A087WWI3_HUMAN,tr|A0A494C0U8|A0A494C0U8_HUMAN,tr|A0A087WSV7|A0A087WSV7_HUMAN,tr|M0QY24|M0QY24_HUMAN,tr|A0A087WVP9|A0A087WVP9_HUMAN,tr|A0A087WVP9|A0A087WVP9_HUMAN,tr|A0A087WVP9|A0A087WVP9_HUMAN,tr|K7EKZ8|K7EKZ8_HUMAN,tr|F8W7T7|F8W7T7_HUMAN,tr|A0A804HI69|A0A804HI69_HUMAN,tr|C9J423|C9J423_HUMAN,tr|A0A087X0M6|A0A087X0M6_HUMAN,tr|K7EQV7|K7EQV7_HUMAN,tr|K7EM63|K7EM63_HUMAN,tr|A0A087WVH9|A0A087WVH9_HUMAN,tr|K7EK80|K7EK80_HUMAN,tr|Q17RW3|Q17RW3_HUMAN,tr|B4DRR6|B4DRR6_HUMAN,tr|B4DRR6|B4DRR6_HUMAN,tr|B4DRR6|B4DRR6_HUMAN" 117 1376.6729 1.19 137980 4227 3 1376.671863 459.8983 Zinc finger protein 699 OS=Homo sapiens OX=9606 GN=ZNF699 PE=1 SV=1 6.75 1389.8 - 1.21E+06 - - - -0.7794 - 2.097 1 - 113.3 3 2 0 -0.0011 11 0 0 0 1.05E+07 8.76E+06 - - - 0.4225 1 221125_WJC_METTL3_EV_vs_WT_F10.04228.04228.3 2.77E-06 17/48 R.QIESTETSC[160.03]HGC[160.03]R.K "sp|Q9Y508|RN114_HUMAN,tr|A0A096LP02|A0A096LP02_HUMAN,tr|A0A096LNV3|A0A096LNV3_HUMAN" 3 1563.6406 2.22 137981 4228 3 1563.638342 522.2208 E3 ubiquitin-protein ligase RNF114 OS=Homo sapiens OX=9606 GN=RNF114 PE=1 SV=1 5.4 1389.9 - 1.06E+06 - - - -1.4377 - 2.637 0.634 - 345.6 1 2 0 -0.0022 13 0 0 0 4.06E+07 1.83E+07 - - - 8.2368 0.9189 221125_WJC_METTL3_EV_vs_WT_F10.04229.04229.2 0.00617 16-Dec A.SDSHRPEVK.L "sp|Q9NYF8|BCLF1_HUMAN,tr|E9PKI6|E9PKI6_HUMAN,tr|A0A1W2PQ43|A0A1W2PQ43_HUMAN,tr|E9PK91|E9PK91_HUMAN,tr|E9PJA7|E9PJA7_HUMAN,tr|E9PK09|E9PK09_HUMAN,tr|E9PQN2|E9PQN2_HUMAN" 7 1053.5203 2.5 137982 4229 2 1053.516564 527.7674 Bcl-2-associated transcription factor 1 OS=Homo sapiens OX=9606 GN=BCLAF1 PE=1 SV=2 6.47 1390.1 - 1.04E+06 - - - -3.5671 - 2.122 0.374 - 700.5 1 1 0 -0.0038 9 0 0 0 7.74E+07 3.10E+07 - - - 3.9788 1 221125_WJC_METTL3_EV_vs_WT_F10.04230.04230.3 2.31E-06 19/48 R.QIESTETSC[160.03]HGC[160.03]R[166.11].K "sp|Q9Y508|RN114_HUMAN,tr|A0A096LP02|A0A096LP02_HUMAN,tr|A0A096LNV3|A0A096LNV3_HUMAN" 3 1573.6489 2.11 137983 4230 3 1573.645851 525.5569 E3 ubiquitin-protein ligase RNF114 OS=Homo sapiens OX=9606 GN=RNF114 PE=1 SV=1 5.4 1390.2 - 891373 - - - -1.9121 - 2.964 0.664 - 724.6 1 2 0 -0.003 13 0 0 0 3.81E+07 1.81E+07 - - - 8.888 1 221125_WJC_METTL3_EV_vs_WT_F10.04231.04231.2 3.62E-06 18/28 K.SSSSGSVGESSSKGP.R "sp|P13645|K1C10_HUMAN,tr|A0A1B0GVI3|A0A1B0GVI3_HUMAN" 2 1338.5899 4660.93 137984 4231 2 1338.589575 670.3022 "Keratin, type I cytoskeletal 10 OS=Homo sapiens OX=9606 GN=KRT10 PE=1 SV=6" 5.72 1390.3 - 813210 - - - -0.2555 - 3.23 0.59 - 956.4 1 1 1 -0.0003 15 0 0 0 1.24E+09 2.66E+05 - - - 6.2812 0.9511 221125_WJC_METTL3_EV_vs_WT_F10.04233.04233.2 0.00422 20-Sep G.TGGPNHPPAPR.G sp|P48634|PRC2A_HUMAN 1 1099.5523 -1 137986 4233 2 1099.550819 550.7834 Protein PRRC2A OS=Homo sapiens OX=9606 GN=PRRC2A PE=1 SV=3 9.44 1390.6 - 275929 - - - -1.3378 - 1.501 0.365 - 206.5 1 1 0 -0.0015 11 0 0 0 0.00E+00 0.00E+00 - - - 2.8351 1 221125_WJC_METTL3_EV_vs_WT_F10.04238.04238.3 2.68E-06 14/52 R.GGGTGGPNHPPAPR[166.11].G sp|P48634|PRC2A_HUMAN 1 1280.625 1.22 137989 4238 3 1280.622378 427.8823 Protein PRRC2A OS=Homo sapiens OX=9606 GN=PRRC2A PE=1 SV=3 9.76 1391.2 - 2.04E+07 - - - -2.01 - 2.557 0.553 - 279.5 1 2 0 -0.0026 14 0 0 0 1.47E+08 1.21E+08 - - - 7.1997 0.9999 221125_WJC_METTL3_EV_vs_WT_F10.04239.04239.3 4.33E-05 Dec-36 K.QQTTVPQK[136.11]PR[166.11].Q "sp|Q9BY77|PDIP3_HUMAN,tr|F6VRR5|F6VRR5_HUMAN,tr|F8WCX5|F8WCX5_HUMAN,tr|Q6R954|Q6R954_HUMAN,tr|Q8WUT1|Q8WUT1_HUMAN,tr|F8WEE2|F8WEE2_HUMAN" 6 1199.6741 1.4 137990 4239 3 1199.671473 400.8987 Polymerase delta-interacting protein 3 OS=Homo sapiens OX=9606 GN=POLDIP3 PE=1 SV=2 11 1391.2 - 2.29E+07 - - - -2.2231 - 2.269 0.432 - 246.6 1 2 0 -0.0027 10 0 0 0 1.19E+09 8.54E+08 - - - 5.7485 0.9997 221125_WJC_METTL3_EV_vs_WT_F10.04240.04240.3 0.000113 13/36 K.QQTTVPQKPR.Q "sp|Q9BY77|PDIP3_HUMAN,tr|F6VRR5|F6VRR5_HUMAN,tr|F8WCX5|F8WCX5_HUMAN,tr|Q6R954|Q6R954_HUMAN,tr|Q8WUT1|Q8WUT1_HUMAN,tr|F8WEE2|F8WEE2_HUMAN" 6 1181.6517 1.4 137991 4240 3 1181.649566 394.8912 Polymerase delta-interacting protein 3 OS=Homo sapiens OX=9606 GN=POLDIP3 PE=1 SV=2 11 1391.3 - 2.18E+07 - - - -1.7806 - 2.204 0.344 - 332.9 1 2 0 -0.0021 10 0 0 0 1.19E+09 8.54E+08 - - - 4.6826 0.9997 221125_WJC_METTL3_EV_vs_WT_F10.04246.04246.2 0.0328 18-Nov K.QQTTVPQKPR.Q "sp|Q9BY77|PDIP3_HUMAN,tr|F6VRR5|F6VRR5_HUMAN,tr|F8WCX5|F8WCX5_HUMAN,tr|Q6R954|Q6R954_HUMAN,tr|Q8WUT1|Q8WUT1_HUMAN,tr|F8WEE2|F8WEE2_HUMAN" 6 1181.6517 1.43 137997 4246 2 1181.650529 591.8331 Polymerase delta-interacting protein 3 OS=Homo sapiens OX=9606 GN=POLDIP3 PE=1 SV=2 11 1391.9 - 1.41E+06 - - - -0.9656 - 2.05 0.355 - 396.6 1 2 0 -0.0011 10 0 0 0 8.36E+07 5.86E+07 - - - 3.6664 0.9985 221125_WJC_METTL3_EV_vs_WT_F10.04247.04247.2 0.00277 18-Nov K.QQTTVPQK[136.11]PR[166.11].Q "sp|Q9BY77|PDIP3_HUMAN,tr|F6VRR5|F6VRR5_HUMAN,tr|F8WCX5|F8WCX5_HUMAN,tr|Q6R954|Q6R954_HUMAN,tr|Q8WUT1|Q8WUT1_HUMAN,tr|F8WEE2|F8WEE2_HUMAN" 6 1199.6741 1.43 137998 4247 2 1199.670609 600.8443 Polymerase delta-interacting protein 3 OS=Homo sapiens OX=9606 GN=POLDIP3 PE=1 SV=2 11 1392 - 1.23E+06 - - - -2.9433 - 2.062 0.313 - 315.3 1 2 0 -0.0035 10 0 0 0 8.36E+07 5.86E+07 - - - 3.3717 0.7678 221125_WJC_METTL3_EV_vs_WT_F10.04249.04249.2 0.00132 18-Dec L.ASDSHR[166.11]PEVK[136.11].L "sp|Q9NYF8|BCLF1_HUMAN,tr|E9PKI6|E9PKI6_HUMAN,tr|A0A1W2PQ43|A0A1W2PQ43_HUMAN,tr|E9PK91|E9PK91_HUMAN,tr|E9PJA7|E9PJA7_HUMAN,tr|E9PK09|E9PK09_HUMAN,tr|E9PQN2|E9PQN2_HUMAN" 7 1142.5799 2.43 138000 4249 2 1142.572838 572.2972 Bcl-2-associated transcription factor 1 OS=Homo sapiens OX=9606 GN=BCLAF1 PE=1 SV=2 6.8 1392.3 - 1.06E+06 - - - -6.1851 - 2.524 0.453 - 550.4 1 1 0 -0.0071 10 0 0 0 9.61E+07 3.95E+07 - - - 4.969 1 221125_WJC_METTL3_EV_vs_WT_F10.04253.04253.2 4.72E-08 14/26 A.AQAAAQTNSNAAGK[136.11].Q sp|Q8NC51|PAIRB_HUMAN 1 1309.6466 0.95 138004 4253 2 1309.642426 655.8306 Plasminogen activator inhibitor 1 RNA-binding protein OS=Homo sapiens OX=9606 GN=SERBP1 PE=1 SV=2 8.8 1392.8 - 410413 - - - -3.1802 - 2.876 0.551 - 509.3 1 1 0 -0.0042 14 0 0 0 2.28E+06 2.41E+06 - - - 5.7604 0.9998 221125_WJC_METTL3_EV_vs_WT_F10.04256.04256.2 0.000336 13/20 R.HSSSVSLSSGK[136.11].K "sp|Q8ND83|SLAI1_HUMAN,tr|X6RGK9|X6RGK9_HUMAN,tr|B7Z326|B7Z326_HUMAN,tr|C9JUW9|C9JUW9_HUMAN,tr|X6RDJ2|X6RDJ2_HUMAN,tr|C9JP03|C9JP03_HUMAN,tr|Q5T6P2|Q5T6P2_HUMAN,tr|A0A0A0MSS3|A0A0A0MSS3_HUMAN,tr|Q5T6P1|Q5T6P1_HUMAN,tr|A0A0C4DFN6|A0A0C4DFN6_HUMAN,tr|C9JD09|C9JD09_HUMAN" 11 1082.5448 1.05 138005 4256 2 1082.54312 542.2797 SLAIN motif-containing protein 1 OS=Homo sapiens OX=9606 GN=SLAIN1 PE=1 SV=3 8.76 1393.2 - 3.73E+06 - - - -1.5076 - 2.019 0.486 - 300.8 1 2 0 -0.0016 11 0 0 0 4.82E+07 4.60E+07 - - - 4.5308 1 221125_WJC_METTL3_EV_vs_WT_F10.04257.04257.2 3.63E-05 16/20 R.HSSSVSLSSGK.K "sp|Q8ND83|SLAI1_HUMAN,tr|X6RGK9|X6RGK9_HUMAN,tr|B7Z326|B7Z326_HUMAN,tr|C9JUW9|C9JUW9_HUMAN,tr|X6RDJ2|X6RDJ2_HUMAN,tr|C9JP03|C9JP03_HUMAN,tr|Q5T6P2|Q5T6P2_HUMAN,tr|A0A0A0MSS3|A0A0A0MSS3_HUMAN,tr|Q5T6P1|Q5T6P1_HUMAN,tr|A0A0C4DFN6|A0A0C4DFN6_HUMAN,tr|C9JD09|C9JD09_HUMAN" 11 1074.5306 1.05 138006 4257 2 1074.527105 538.2726 SLAIN motif-containing protein 1 OS=Homo sapiens OX=9606 GN=SLAIN1 PE=1 SV=3 8.76 1393.3 - 3.15E+06 - - - -3.2079 - 2.819 0.565 - 601.8 1 2 0 -0.0034 11 0 0 0 4.82E+07 4.60E+07 - - - 6.0167 0.7868 221125_WJC_METTL3_EV_vs_WT_F10.04260.04260.3 0.977 28-Jun R.EEIHEYR[166.11]R[166.11].Q sp|Q16352|AINX_HUMAN 1 1150.5634 0.001 138009 4260 3 1150.564618 384.5284 Alpha-internexin OS=Homo sapiens OX=9606 GN=INA PE=1 SV=2 5.5 1393.5 - 973665 - - - 1.0491 - 1.166 0.091 - 90.3 1 2 0 0.0012 8 0 0 0 0.00E+00 1.58E+07 - - - 0.0342 0.9905 221125_WJC_METTL3_EV_vs_WT_F10.04261.04261.3 0.0339 14/40 K.QLIDKETNDRK.C sp|P15924|DESP_HUMAN 1 1358.7154 999 138010 4261 3 1358.711979 453.9124 Desmoplakin OS=Homo sapiens OX=9606 GN=DSP PE=1 SV=3 6.12 1393.6 - 757451 - - - -2.5127 - 2.157 0.247 - 242.4 1 2 1 -0.0034 11 0 0 0 2.45E+07 0.00E+00 - - - 3.4767 0.9938 221125_WJC_METTL3_EV_vs_WT_F10.04262.04262.2 4.34E-05 20-Nov M.IASDSHRPEVK.L "sp|Q9NYF8|BCLF1_HUMAN,tr|E9PKI6|E9PKI6_HUMAN,tr|A0A1W2PQ43|A0A1W2PQ43_HUMAN,tr|E9PK91|E9PK91_HUMAN,tr|E9PJA7|E9PJA7_HUMAN,tr|E9PK09|E9PK09_HUMAN,tr|E9PQN2|E9PQN2_HUMAN" 7 1237.6415 2.95 138011 4262 2 1237.640712 619.828 Bcl-2-associated transcription factor 1 OS=Homo sapiens OX=9606 GN=BCLAF1 PE=1 SV=2 6.75 1393.7 - 537765 - - - -0.6359 - 2.476 0.511 - 416 1 1 0 -0.0008 11 0 0 0 1.30E+07 4.39E+06 - - - 5.2677 1 221125_WJC_METTL3_EV_vs_WT_F10.04271.04271.3 2.51E-07 15/60 K.SAAQAAAQTNSNAAGK[136.11].Q sp|Q8NC51|PAIRB_HUMAN 1 1467.7157 0.91 138016 4271 3 1467.712372 490.2459 Plasminogen activator inhibitor 1 RNA-binding protein OS=Homo sapiens OX=9606 GN=SERBP1 PE=1 SV=2 8.47 1394.7 - 1.19E+07 - - - -2.2906 - 2.858 0.569 - 292.1 1 2 0 -0.0034 16 0 0 0 4.00E+08 4.39E+08 - - - 7.5773 1 221125_WJC_METTL3_EV_vs_WT_F10.04273.04273.3 8.09E-06 15/44 K.MSSPEDDSDTKR.L sp|Q15424|SAFB1_HUMAN 1 1366.5671 104.1 138018 4273 3 1366.567032 456.5296 Scaffold attachment factor B1 OS=Homo sapiens OX=9606 GN=SAFB PE=1 SV=4 4.23 1395 - 937014 - - - -0.03 - 2.632 0.539 - 366.8 1 2 0 0 12 0 0 0 3.64E+07 3.49E+05 - - - 7.2317 0.9937 221125_WJC_METTL3_EV_vs_WT_F10.04282.04282.2 1.46E-05 15/18 L.ASDSHRPEVK.L "sp|Q9NYF8|BCLF1_HUMAN,tr|E9PKI6|E9PKI6_HUMAN,tr|A0A1W2PQ43|A0A1W2PQ43_HUMAN,tr|E9PK91|E9PK91_HUMAN,tr|E9PJA7|E9PJA7_HUMAN,tr|E9PK09|E9PK09_HUMAN,tr|E9PQN2|E9PQN2_HUMAN" 7 1124.5574 2.41 138025 4282 2 1124.556472 563.286 Bcl-2-associated transcription factor 1 OS=Homo sapiens OX=9606 GN=BCLAF1 PE=1 SV=2 6.8 1395.8 - 3.24E+06 - - - -0.8563 - 2.81 0.468 - 989.4 1 1 0 -0.001 10 0 0 0 9.63E+07 4.00E+07 - - - 5.3813 1 221125_WJC_METTL3_EV_vs_WT_F10.04283.04283.3 8.45E-06 20/44 K.HLTHAQSTLDAK[136.11].A sp|Q15125|EBP_HUMAN 1 1328.6928 5.81 138026 4283 3 1328.690491 443.9049 "3-beta-hydroxysteroid-Delta(8),Delta(7)-isomerase OS=Homo sapiens OX=9606 GN=EBP PE=1 SV=3" 6.92 1395.9 - 1.47E+06 - - - -1.7476 - 3.789 0.397 - 673.6 1 2 0 -0.0023 12 0 0 0 8.97E+07 1.55E+07 - - - 6.6579 0.9999 221125_WJC_METTL3_EV_vs_WT_F10.04289.04289.3 0.000145 14/36 K.LHEEHINAGR.T "sp|P56962|STX17_HUMAN,tr|E9PJV6|E9PJV6_HUMAN,tr|E9PIC2|E9PIC2_HUMAN" 3 1174.5843 0.55 138030 4289 3 1174.581995 392.5354 Syntaxin-17 OS=Homo sapiens OX=9606 GN=STX17 PE=1 SV=2 6 1396.7 - 1.23E+06 - - - -1.9786 - 2.338 0.433 - 199.4 1 2 0 -0.0023 10 0 0 0 2.76E+07 4.98E+07 - - - 5.8472 0.9905 221125_WJC_METTL3_EV_vs_WT_F10.04298.04298.2 0.000162 13/16 A.SDSHR[166.11]PEVK[136.11].L "sp|Q9NYF8|BCLF1_HUMAN,tr|E9PKI6|E9PKI6_HUMAN,tr|A0A1W2PQ43|A0A1W2PQ43_HUMAN,tr|E9PK91|E9PK91_HUMAN,tr|E9PJA7|E9PJA7_HUMAN,tr|E9PK09|E9PK09_HUMAN,tr|E9PQN2|E9PQN2_HUMAN" 7 1071.5428 2.5 138037 4298 2 1071.542603 536.7787 Bcl-2-associated transcription factor 1 OS=Homo sapiens OX=9606 GN=BCLAF1 PE=1 SV=2 6.47 1397.6 - 1.07E+06 - - - -0.1764 - 2.381 0.384 - 894.2 1 1 0 -0.0002 9 0 0 0 7.74E+07 3.10E+07 - - - 4.3869 1 221125_WJC_METTL3_EV_vs_WT_F10.04299.04299.3 3.02E-06 13/52 K.NHEAGTSGC[160.03]GIDAK[136.11].Q "sp|Q5SW79|CE170_HUMAN,tr|H0Y2V6|H0Y2V6_HUMAN" 2 1423.6241 0.8 138038 4299 3 1423.621227 475.5487 Centrosomal protein of 170 kDa OS=Homo sapiens OX=9606 GN=CEP170 PE=1 SV=1 5.32 1397.8 - 977437 - - - -2.0476 - 2.815 0.612 - 321.4 1 2 0 -0.0029 14 0 0 0 1.13E+07 1.41E+07 - - - 8.1128 0.8251 221125_WJC_METTL3_EV_vs_WT_F10.04304.04304.3 0.0122 Sep-36 L.ASDSHR[166.11]PEVK[136.11].L "sp|Q9NYF8|BCLF1_HUMAN,tr|E9PKI6|E9PKI6_HUMAN,tr|A0A1W2PQ43|A0A1W2PQ43_HUMAN,tr|E9PK91|E9PK91_HUMAN,tr|E9PJA7|E9PJA7_HUMAN,tr|E9PK09|E9PK09_HUMAN,tr|E9PQN2|E9PQN2_HUMAN" 7 1142.5799 0.001 138041 4304 3 1142.577836 381.8672 Bcl-2-associated transcription factor 1 OS=Homo sapiens OX=9606 GN=BCLAF1 PE=1 SV=2 6.8 1398.4 - 1.38E+06 - - - -1.8108 - 1.92 0.242 - 132.5 1 1 0 -0.0021 10 0 0 0 0.00E+00 3.31E+07 - - - 3.1426 0.9219 221125_WJC_METTL3_EV_vs_WT_F10.04305.04305.3 0.47 Oct-36 K.SYTHPSSLRK.H "sp|O60481|ZIC3_HUMAN,sp|Q96T25|ZIC5_HUMAN,sp|O95409|ZIC2_HUMAN,sp|Q15915|ZIC1_HUMAN,tr|H7C5D8|H7C5D8_HUMAN" 5 1174.6095 0.86 138042 4305 3 1174.609382 392.5438 Zinc finger protein ZIC 3 OS=Homo sapiens OX=9606 GN=ZIC3 PE=1 SV=1 9.99 1398.5 - 1.04E+06 - - - -0.0758 - 1.268 0.122 - 97.7 1 2 0 -0.0001 10 0 0 0 2.12E+07 2.45E+07 - - - 0.5936 0.9996 221125_WJC_METTL3_EV_vs_WT_F10.04316.04316.3 0.000814 Sep-48 R.QETTHGQTINTTR.H sp|Q5D862|FILA2_HUMAN 1 1485.7172 59.73 138051 4316 3 1485.714016 496.2463 Filaggrin-2 OS=Homo sapiens OX=9606 GN=FLG2 PE=1 SV=1 6.75 1399.9 - 816617 - - - -2.1323 - 1.788 0.397 - 97.2 1 2 0 -0.0032 13 0 0 0 1.36E+07 2.27E+05 - - - 4.5408 1 221125_WJC_METTL3_EV_vs_WT_F10.04317.04317.2 3.35E-07 22-Oct K.QSEAENTEQVNK.N "sp|Q9NRY5|F1142_HUMAN,tr|E7ESJ7|E7ESJ7_HUMAN" 2 1375.6216 1.83 138052 4317 2 1375.62163 688.8181 Protein FAM114A2 OS=Homo sapiens OX=9606 GN=FAM114A2 PE=1 SV=4 4.25 1400 - 358023 - - - 0.0567 - 2.398 0.619 - 383.5 1 2 0 0.0001 12 0 0 0 4.81E+06 2.62E+06 - - - 5.9142 0.9821 221125_WJC_METTL3_EV_vs_WT_F10.04318.04318.2 0.0406 22-Oct R.DLQGR[166.11]DEQSEEK[136.11].K sp|P35579|MYH9_HUMAN 1 1450.6655 1.09 138053 4318 2 1450.664045 726.34 Myosin-9 OS=Homo sapiens OX=9606 GN=MYH9 PE=1 SV=4 4.18 1400.1 - 305936 - - - -0.9933 - 2.1 0.151 - 210.3 1 2 1 -0.0014 12 0 0 0 4.71E+06 4.33E+06 - - - 2.108 0.9998 221125_WJC_METTL3_EV_vs_WT_F10.04324.04324.3 0.00127 Dec-36 R.QVHSTER[166.11]PFK[136.11].C "sp|P56270|MAZ_HUMAN,tr|H3BQI4|H3BQI4_HUMAN,tr|H3BQS2|H3BQS2_HUMAN,tr|I3L2Z5|I3L2Z5_HUMAN,tr|A0A087WWR2|A0A087WWR2_HUMAN" 5 1245.6585 1.22 138057 4324 3 1245.655632 416.2268 Myc-associated zinc finger protein OS=Homo sapiens OX=9606 GN=MAZ PE=1 SV=1 8.75 1401 - 1.72E+06 - - - -2.2944 - 2.117 0.417 - 196.3 1 2 0 -0.0029 10 0 0 0 1.93E+08 1.58E+08 - - - 5.3787 0.9929 221125_WJC_METTL3_EV_vs_WT_F10.04326.04326.3 0.102 Nov-32 R.K[136.11]HQQLLEEK[136.11].N sp|P35580|MYH10_HUMAN 1 1167.6583 1.09 138059 4326 3 1167.654404 390.2267 Myosin-10 OS=Homo sapiens OX=9606 GN=MYH10 PE=1 SV=3 6.76 1401.2 - 338085 - - - -3.3126 - 1.808 0.242 - 183.6 1 2 0 -0.0039 9 0 0 0 2.97E+07 2.72E+07 - - - 3.0218 0.7641 221125_WJC_METTL3_EV_vs_WT_F10.04328.04328.3 0.217 Aug-32 R.KHQQLLEEK.N sp|P35580|MYH10_HUMAN 1 1151.6299 1.09 138061 4328 3 1151.627475 384.8839 Myosin-10 OS=Homo sapiens OX=9606 GN=MYH10 PE=1 SV=3 6.76 1401.4 - 289740 - - - -2.0814 - 1.533 0.05 - 79.5 2 2 0 -0.0024 9 0 0 0 2.97E+07 2.72E+07 - - - 0.245 0.9997 221125_WJC_METTL3_EV_vs_WT_F10.04329.04329.2 0.000132 18-Aug R.LGNDFHTNK[136.11]R[166.11].V "sp|P08708|RS17_HUMAN,tr|H0YN73|H0YN73_HUMAN,tr|H3BNC9|H3BNC9_HUMAN,tr|A0A0J9YYC4|A0A0J9YYC4_HUMAN,tr|H0YN88|H0YN88_HUMAN,tr|A0A075B716|A0A075B716_HUMAN" 6 1218.6224 1.33 138062 4329 2 1218.620354 610.3185 40S ribosomal protein S17 OS=Homo sapiens OX=9606 GN=RPS17 PE=1 SV=2 8.75 1401.6 - 194760 - - - -1.7109 - 1.812 0.514 - 286.8 1 2 0 -0.0021 10 0 0 0 9.65E+07 7.26E+07 - - - 4.496 0.9618 221125_WJC_METTL3_EV_vs_WT_F10.04333.04333.3 2.21 Dec-36 R.QVHSTERPFK.C "sp|P56270|MAZ_HUMAN,tr|H3BQI4|H3BQI4_HUMAN,tr|H3BQS2|H3BQS2_HUMAN,tr|I3L2Z5|I3L2Z5_HUMAN,tr|A0A087WWR2|A0A087WWR2_HUMAN" 5 1227.636 1.22 138064 4333 3 1227.634358 410.2193 Myc-associated zinc finger protein OS=Homo sapiens OX=9606 GN=MAZ PE=1 SV=1 8.75 1402.1 - 3.30E+06 - - - -1.3538 - 1.876 0.066 - 138.7 1 2 0 -0.0017 10 0 0 0 1.93E+08 1.59E+08 - - - 1.1127 0.9889 221125_WJC_METTL3_EV_vs_WT_F10.04337.04337.2 8.58E-09 16-Nov L.GNDFHTNKR.V "sp|P08708|RS17_HUMAN,tr|H0YN73|H0YN73_HUMAN,tr|H3BNC9|H3BNC9_HUMAN,tr|A0A0J9YYC4|A0A0J9YYC4_HUMAN,tr|H0YN88|H0YN88_HUMAN,tr|A0A075B716|A0A075B716_HUMAN" 6 1087.5159 1.44 138067 4337 2 1087.513854 544.7652 40S ribosomal protein S17 OS=Homo sapiens OX=9606 GN=RPS17 PE=1 SV=2 8.75 1402.5 - 917268 - - - -1.8859 - 2.198 0.549 - 692.6 1 1 0 -0.0021 9 0 0 0 1.28E+08 8.85E+07 - - - 5.3737 1 221125_WJC_METTL3_EV_vs_WT_F10.04338.04338.2 7.38E-09 16-Nov L.GNDFHTNK[136.11]R[166.11].V "sp|P08708|RS17_HUMAN,tr|H0YN73|H0YN73_HUMAN,tr|H3BNC9|H3BNC9_HUMAN,tr|A0A0J9YYC4|A0A0J9YYC4_HUMAN,tr|H0YN88|H0YN88_HUMAN,tr|A0A075B716|A0A075B716_HUMAN" 6 1105.5384 1.45 138068 4338 2 1105.536985 553.7765 40S ribosomal protein S17 OS=Homo sapiens OX=9606 GN=RPS17 PE=1 SV=2 8.75 1402.6 - 798348 - - - -1.2573 - 2.111 0.67 - 689.3 1 1 0 -0.0014 9 0 0 0 1.28E+08 8.85E+07 - - - 6.1508 0.9979 221125_WJC_METTL3_EV_vs_WT_F10.04339.04339.3 0.0526 Oct-36 R.LGNDFHTNKR[166.11].V "sp|P08708|RS17_HUMAN,tr|H0YN73|H0YN73_HUMAN,tr|H3BNC9|H3BNC9_HUMAN,tr|A0A0J9YYC4|A0A0J9YYC4_HUMAN,tr|H0YN88|H0YN88_HUMAN,tr|A0A075B716|A0A075B716_HUMAN" 6 1210.6082 - 138069 4339 3 1210.607126 404.5434 40S ribosomal protein S17 OS=Homo sapiens OX=9606 GN=RPS17 PE=1 SV=2 8.75 1402.7 - 754220 - - - -0.9194 - 2.033 0.196 - 90.2 1 2 0 -0.0011 10 0 0 0 - - - - - 2.797 0.9993 221125_WJC_METTL3_EV_vs_WT_F10.04343.04343.2 0.00308 20-Jun R.SQPQQPSQPQR[166.11].T "sp|Q7Z589|EMSY_HUMAN,tr|H0YCS3|H0YCS3_HUMAN,tr|E9PMC9|E9PMC9_HUMAN" 3 1289.6352 1.67 138073 4343 2 1289.635128 645.8249 BRCA2-interacting transcriptional repressor EMSY OS=Homo sapiens OX=9606 GN=EMSY PE=1 SV=2 9.47 1403.2 - 173050 - - - -0.0419 - 1.359 0.374 - 120.6 1 2 0 -0.0001 11 0 0 0 3.34E+06 2.01E+06 - - - 2.6332 0.9738 221125_WJC_METTL3_EV_vs_WT_F10.04346.04346.2 2.69E-06 14-Dec G.NDFHTNK[136.11]R[166.11].V "sp|P08708|RS17_HUMAN,tr|H0YN73|H0YN73_HUMAN,tr|H3BNC9|H3BNC9_HUMAN,tr|A0A0J9YYC4|A0A0J9YYC4_HUMAN,tr|H0YN88|H0YN88_HUMAN,tr|A0A075B716|A0A075B716_HUMAN" 6 1048.5169 1.64 138074 4346 2 1048.515427 525.2657 40S ribosomal protein S17 OS=Homo sapiens OX=9606 GN=RPS17 PE=1 SV=2 8.75 1403.6 - 1.24E+06 - - - -1.4153 - 2.127 0.304 - 765.8 1 1 0 -0.0015 8 0 0 0 4.83E+07 2.95E+07 - - - 3.5621 1 221125_WJC_METTL3_EV_vs_WT_F10.04348.04348.2 6.49E-10 17/28 K.AVQAQGGESQQEAQR.L "sp|Q14980|NUMA1_HUMAN,tr|A0A087WY61|A0A087WY61_HUMAN,tr|H0YFY6|H0YFY6_HUMAN,tr|K4DIE0|K4DIE0_HUMAN" 4 1585.7445 1.4 138076 4348 2 1585.742435 793.8795 Nuclear mitotic apparatus protein 1 OS=Homo sapiens OX=9606 GN=NUMA1 PE=1 SV=2 4.53 1403.8 - 772367 - - - -1.2776 - 3.213 0.649 - 1049 1 2 0 -0.002 15 0 0 0 5.56E+06 3.98E+06 - - - 6.7035 0.9919 221125_WJC_METTL3_EV_vs_WT_F10.04350.04350.2 1.95E-06 26-Oct R.SSSSGQHGSGLGES.S "sp|Q86YZ3|HORN_HUMAN,sp|Q86YZ3|HORN_HUMAN,sp|Q86YZ3|HORN_HUMAN" 3 1275.5327 - 138078 4350 2 1275.530997 638.7736 Hornerin OS=Homo sapiens OX=9606 GN=HRNR PE=1 SV=2 5.22 1404.1 - 430417 - - - -1.3641 - 2.156 0.591 - 231.5 1 1 0 -0.0017 14 0 0 0 - - - - - 5.3335 1 221125_WJC_METTL3_EV_vs_WT_F10.04351.04351.2 2.19E-07 13/28 K.AVQAQGGESQQEAQR[166.11].L "sp|Q14980|NUMA1_HUMAN,tr|A0A087WY61|A0A087WY61_HUMAN,tr|H0YFY6|H0YFY6_HUMAN,tr|K4DIE0|K4DIE0_HUMAN" 4 1595.7527 1.4 138079 4351 2 1595.748924 798.8836 Nuclear mitotic apparatus protein 1 OS=Homo sapiens OX=9606 GN=NUMA1 PE=1 SV=2 4.53 1404.2 - 400715 - - - -2.3857 - 2.803 0.588 - 513 1 2 0 -0.0038 15 0 0 0 5.56E+06 3.98E+06 - - - 5.9168 0.9995 221125_WJC_METTL3_EV_vs_WT_F10.04352.04352.2 1.42E-05 20-Oct R.GRPAVC[160.03]QPQGR.F sp|Q5T749|KPRP_HUMAN 1 1224.6146 293.08 138080 4352 2 1224.610893 613.3146 Keratinocyte proline-rich protein OS=Homo sapiens OX=9606 GN=KPRP PE=1 SV=1 10.35 1404.3 - 384455 - - - -3.005 - 1.984 0.549 - 117.6 1 2 0 -0.0037 11 0 0 0 7.50E+06 2.56E+04 - - - 4.9482 1 221125_WJC_METTL3_EV_vs_WT_F10.04353.04353.2 7.81E-09 26-Nov Y.SGSSSSGSSISSAR.S "sp|Q15517|CDSN_HUMAN,tr|G8JLG2|G8JLG2_HUMAN,tr|Q2L6G8|Q2L6G8_HUMAN" 3 1255.564 999 138081 4353 2 1255.563471 628.7893 Corneodesmosin OS=Homo sapiens OX=9606 GN=CDSN PE=1 SV=3 9.47 1404.5 - 292602 - - - -0.4508 - 2.548 0.651 - 400.4 1 1 0 -0.0006 14 0 0 0 2.32E+06 0.00E+00 - - - 6.1962 0.9667 221125_WJC_METTL3_EV_vs_WT_F10.04359.04359.2 0.00814 14-Sep G.NDFHTNKR.V "sp|P08708|RS17_HUMAN,tr|H0YN73|H0YN73_HUMAN,tr|H3BNC9|H3BNC9_HUMAN,tr|A0A0J9YYC4|A0A0J9YYC4_HUMAN,tr|H0YN88|H0YN88_HUMAN,tr|A0A075B716|A0A075B716_HUMAN" 6 1030.4944 1.64 138085 4359 2 1030.492635 516.2545 40S ribosomal protein S17 OS=Homo sapiens OX=9606 GN=RPS17 PE=1 SV=2 8.75 1405.2 - 3.25E+06 - - - -1.7526 - 1.675 0.396 - 399.2 1 1 0 -0.0018 8 0 0 0 4.83E+07 2.95E+07 - - - 3.521 0.9991 221125_WJC_METTL3_EV_vs_WT_F10.04365.04365.2 0.034 18-Aug R.QVHSTER[166.11]PFK[136.11].C "sp|P56270|MAZ_HUMAN,tr|H3BQI4|H3BQI4_HUMAN,tr|H3BQS2|H3BQS2_HUMAN,tr|I3L2Z5|I3L2Z5_HUMAN,tr|A0A087WWR2|A0A087WWR2_HUMAN" 5 1245.6585 1.39 138091 4365 2 1245.659014 623.8365 Myc-associated zinc finger protein OS=Homo sapiens OX=9606 GN=MAZ PE=1 SV=1 8.75 1405.8 - 345890 - - - 0.4207 - 1.447 0.335 - 189.3 1 2 0 0.0005 10 0 0 0 9.43E+06 6.78E+06 - - - 2.5465 0.9921 221125_WJC_METTL3_EV_vs_WT_F10.04368.04368.3 0.216 Sep-44 K.LNGNLRPHGDNR.T "sp|Q8WXI9|P66B_HUMAN,tr|A0A0U1RR34|A0A0U1RR34_HUMAN,tr|A0A0U1RRM1|A0A0U1RRM1_HUMAN,tr|A0A0U1RRK3|A0A0U1RRK3_HUMAN" 4 1361.6912 2.42 138093 4368 3 1361.688724 454.9044 Transcriptional repressor p66-beta OS=Homo sapiens OX=9606 GN=GATAD2B PE=1 SV=1 9.61 1406.2 - 2.11E+06 - - - -1.8506 - 1.562 0.222 - 109.9 1 2 0 -0.0025 12 0 0 0 4.03E+07 1.67E+07 - - - 2.2505 0.9806 221125_WJC_METTL3_EV_vs_WT_F10.04369.04369.3 0.144 Sep-52 R.GVGSGGQGPPPPRR.E sp|P48634|PRC2A_HUMAN 1 1317.6902 0.84 138094 4369 3 1317.689687 440.2373 Protein PRRC2A OS=Homo sapiens OX=9606 GN=PRRC2A PE=1 SV=3 12 1406.3 - 907848 - - - -0.3749 - 1.518 0.158 - 66.4 1 2 0 -0.0005 14 0 0 0 4.09E+07 4.86E+07 - - - 1.4106 0.8559 221125_WJC_METTL3_EV_vs_WT_F10.04371.04371.2 0.764 12-Jul M.YEEHLKR.M "sp|P84090|ERH_HUMAN,tr|G3V279|G3V279_HUMAN" 2 973.4981 2.39 138096 4371 2 973.496357 487.7563 Enhancer of rudimentary homolog OS=Homo sapiens OX=9606 GN=ERH PE=1 SV=1 6.76 1406.5 - 2.17E+06 - - - -1.8213 - 1.502 0.232 - 229.6 1 1 0 -0.0018 7 0 0 0 7.14E+07 2.98E+07 - - - 2.043 0.8154 221125_WJC_METTL3_EV_vs_WT_F10.04374.04374.2 0.000129 12-Jul M.YEEHLK[136.11]R[166.11].M "sp|P84090|ERH_HUMAN,tr|G3V279|G3V279_HUMAN" 2 991.5206 2.39 138099 4374 2 991.517971 496.7676 Enhancer of rudimentary homolog OS=Homo sapiens OX=9606 GN=ERH PE=1 SV=1 6.76 1406.8 - 1.14E+06 - - - -2.6515 - 1.428 0.288 - 193.6 1 1 0 -0.0026 7 0 0 0 7.14E+07 2.98E+07 - - - 2.2962 0.9999 221125_WJC_METTL3_EV_vs_WT_F10.04375.04375.3 2.04E-07 15/48 R.VTSAHK[136.11]GPDETLR[166.11].L "sp|P22234|PUR6_HUMAN,tr|D6RF62|D6RF62_HUMAN,tr|E9PBS1|E9PBS1_HUMAN" 3 1427.7488 0.84 138100 4375 3 1427.746436 476.9235 Multifunctional protein ADE2 OS=Homo sapiens OX=9606 GN=PAICS PE=1 SV=3 6.72 1406.9 - 905193 - - - -1.6291 - 2.599 0.518 - 288.9 1 2 1 -0.0023 13 0 0 0 3.65E+07 4.35E+07 - - - 6.9042 0.9976 221125_WJC_METTL3_EV_vs_WT_F10.04382.04382.2 9.10E-05 15/16 R.HGDSLKEIK.L sp|P35908|K22E_HUMAN 1 1025.5506 172.18 138105 4382 2 1025.548911 513.7826 "Keratin, type II cytoskeletal 2 epidermal OS=Homo sapiens OX=9606 GN=KRT2 PE=1 SV=2" 6.75 1407.7 - 1.20E+06 - - - -1.6069 - 2.463 0.418 - 701 1 2 1 -0.0016 9 0 0 0 2.49E+07 1.45E+05 - - - 4.7356 0.9998 221125_WJC_METTL3_EV_vs_WT_F10.04383.04383.3 9.79E-06 14/48 R.VTSAHKGPDETLR.L "sp|P22234|PUR6_HUMAN,tr|D6RF62|D6RF62_HUMAN,tr|E9PBS1|E9PBS1_HUMAN" 3 1409.7263 0.76 138106 4383 3 1409.724378 470.916 Multifunctional protein ADE2 OS=Homo sapiens OX=9606 GN=PAICS PE=1 SV=3 6.72 1407.8 - 1.04E+06 - - - -1.3577 - 2.535 0.475 - 231.3 1 2 1 -0.0019 13 0 0 0 3.28E+07 4.31E+07 - - - 6.3573 0.9932 221125_WJC_METTL3_EV_vs_WT_F10.04384.04384.2 0.269 18-Sep R.QVHSTERPFK.C "sp|P56270|MAZ_HUMAN,tr|H3BQI4|H3BQI4_HUMAN,tr|H3BQS2|H3BQS2_HUMAN,tr|I3L2Z5|I3L2Z5_HUMAN,tr|A0A087WWR2|A0A087WWR2_HUMAN" 5 1227.636 1.39 138107 4384 2 1227.633653 614.8253 Myc-associated zinc finger protein OS=Homo sapiens OX=9606 GN=MAZ PE=1 SV=1 8.75 1408 - 550220 - - - -1.9281 - 1.318 0.215 - 185.2 1 2 0 -0.0024 10 0 0 0 9.43E+06 6.78E+06 - - - 1.399 0.9994 221125_WJC_METTL3_EV_vs_WT_F10.04385.04385.2 5.15E-07 13/26 R.DTSPSSGSAVSSSK.V "sp|Q8NEY8|PPHLN_HUMAN,tr|B7Z8L1|B7Z8L1_HUMAN,tr|F8W6A0|F8W6A0_HUMAN,tr|F8W0Q9|F8W0Q9_HUMAN,tr|F8WF16|F8WF16_HUMAN" 5 1295.5841 1.74 138108 4385 2 1295.579452 648.7993 Periphilin-1 OS=Homo sapiens OX=9606 GN=PPHLN1 PE=1 SV=2 5.84 1408.1 - 387713 - - - -3.5907 - 2.245 0.624 - 640.1 1 2 0 -0.0047 14 0 0 0 1.41E+07 8.08E+06 - - - 5.6778 1 221125_WJC_METTL3_EV_vs_WT_F10.04391.04391.3 3.80E-06 13/40 R.QDGGQNESFKR.Y "sp|Q7L014|DDX46_HUMAN,tr|A0A0C4DG89|A0A0C4DG89_HUMAN" 2 1264.5796 2.8 138112 4391 3 1264.577303 422.5338 Probable ATP-dependent RNA helicase DDX46 OS=Homo sapiens OX=9606 GN=DDX46 PE=1 SV=2 6.07 1408.8 - 2.31E+06 - - - -1.8378 - 2.449 0.508 - 349.6 1 2 0 -0.0023 11 0 0 0 1.86E+07 6.62E+06 - - - 6.7475 0.9999 221125_WJC_METTL3_EV_vs_WT_F10.04392.04392.3 6.23E-05 Dec-44 K.LNGNLR[166.11]PHGDNR[166.11].T "sp|Q8WXI9|P66B_HUMAN,tr|A0A0U1RR34|A0A0U1RR34_HUMAN,tr|A0A0U1RRM1|A0A0U1RRM1_HUMAN,tr|A0A0U1RRK3|A0A0U1RRK3_HUMAN" 4 1381.7078 2.39 138113 4392 3 1381.70642 461.5765 Transcriptional repressor p66-beta OS=Homo sapiens OX=9606 GN=GATAD2B PE=1 SV=1 9.61 1408.8 - 1.26E+06 - - - -0.9872 - 2.087 0.444 - 194.1 1 2 0 -0.0014 12 0 0 0 3.99E+07 1.67E+07 - - - 5.5291 0.9964 221125_WJC_METTL3_EV_vs_WT_F10.04395.04395.3 0.00745 Aug-40 K.SQKDDEEQIAK.Y "sp|Q9H501|ESF1_HUMAN,tr|A0A087WX71|A0A087WX71_HUMAN" 2 1289.6099 0.99 138116 4395 3 1289.609943 430.8773 ESF1 homolog OS=Homo sapiens OX=9606 GN=ESF1 PE=1 SV=1 4.32 1409.2 - 431834 - - - 0.014 - 1.627 0.32 - 86.6 1 2 1 0 11 0 0 0 2.91E+07 2.95E+07 - - - 3.4904 0.9998 221125_WJC_METTL3_EV_vs_WT_F10.04399.04399.2 6.50E-05 26-Dec R.DTSPSSGSAVSSSK[136.11].V "sp|Q8NEY8|PPHLN_HUMAN,tr|B7Z8L1|B7Z8L1_HUMAN,tr|F8W6A0|F8W6A0_HUMAN,tr|F8W0Q9|F8W0Q9_HUMAN,tr|F8WF16|F8WF16_HUMAN" 5 1303.5983 1.73 138118 4399 2 1303.596772 652.8064 Periphilin-1 OS=Homo sapiens OX=9606 GN=PPHLN1 PE=1 SV=2 5.84 1409.7 - 1.15E+06 - - - -1.1752 - 2.142 0.536 - 507.1 1 2 0 -0.0015 14 0 0 0 1.40E+07 8.08E+06 - - - 4.911 0.996 221125_WJC_METTL3_EV_vs_WT_F10.04400.04400.3 0.000362 Aug-40 K.SQK[136.11]DDEEQIAK[136.11].Y "sp|Q9H501|ESF1_HUMAN,tr|A0A087WX71|A0A087WX71_HUMAN" 2 1305.6383 0.99 138119 4400 3 1305.632951 436.2201 ESF1 homolog OS=Homo sapiens OX=9606 GN=ESF1 PE=1 SV=1 4.32 1409.8 - 1.68E+06 - - - -4.116 - 1.873 0.435 - 92.6 1 2 1 -0.0054 11 0 0 0 2.91E+07 2.95E+07 - - - 5.1711 1 221125_WJC_METTL3_EV_vs_WT_F10.04405.04405.3 4.66E-05 13/48 R.THSQGGYGSQGYK.Y "sp|Q9Y285|SYFA_HUMAN,tr|K7EPH2|K7EPH2_HUMAN,tr|K7ER00|K7ER00_HUMAN,tr|K7ERS0|K7ERS0_HUMAN" 4 1368.6058 1.39 138122 4405 3 1368.604458 457.2092 Phenylalanine--tRNA ligase alpha subunit OS=Homo sapiens OX=9606 GN=FARSA PE=1 SV=3 8.2 1410.5 - 4.34E+06 - - - -1.0112 - 2.2 0.577 - 150.4 1 2 0 -0.0014 13 0 0 0 4.87E+07 3.51E+07 - - - 7.1103 0.9999 221125_WJC_METTL3_EV_vs_WT_F10.04406.04406.3 0.00117 Nov-48 R.THSQGGYGSQGYK[136.11].Y "sp|Q9Y285|SYFA_HUMAN,tr|K7EPH2|K7EPH2_HUMAN,tr|K7ER00|K7ER00_HUMAN,tr|K7ERS0|K7ERS0_HUMAN" 4 1376.62 1.39 138123 4406 3 1376.618156 459.8806 Phenylalanine--tRNA ligase alpha subunit OS=Homo sapiens OX=9606 GN=FARSA PE=1 SV=3 8.2 1410.6 - 3.25E+06 - - - -1.37 - 1.862 0.524 - 105.2 1 2 0 -0.0019 13 0 0 0 4.85E+07 3.48E+07 - - - 6.067 0.9869 221125_WJC_METTL3_EV_vs_WT_F10.04409.04409.2 7.94E-06 20-Oct K.SQKDDEEQIAK.Y "sp|Q9H501|ESF1_HUMAN,tr|A0A087WX71|A0A087WX71_HUMAN" 2 1289.6099 1.09 138126 4409 2 1289.604837 645.8122 ESF1 homolog OS=Homo sapiens OX=9606 GN=ESF1 PE=1 SV=1 4.32 1410.9 - 415671 - - - -3.9454 - 1.898 0.533 - 355.2 1 2 1 -0.0051 11 0 0 0 3.47E+06 3.18E+06 - - - 4.7097 0.9984 221125_WJC_METTL3_EV_vs_WT_F10.04410.04410.3 0.211 Nov-32 R.RIEIEENKK.Q "sp|Q8N5U6|RNF10_HUMAN,tr|H0YG28|H0YG28_HUMAN,tr|H0YFQ9|H0YFQ9_HUMAN,tr|H0YGX5|H0YGX5_HUMAN" 4 1157.6404 1.19 138127 4410 3 1157.640075 386.8874 RING finger protein 10 OS=Homo sapiens OX=9606 GN=RNF10 PE=1 SV=2 6.23 1411.1 - 398996 - - - -0.3127 - 1.861 0.231 - 153.5 1 2 0 -0.0004 9 0 0 0 3.48E+06 2.92E+06 - - - 2.9872 0.9994 221125_WJC_METTL3_EV_vs_WT_F10.04411.04411.2 0.00014 22-Aug K.EGEEQLQTQHQK[136.11].T "sp|P30876|RPB2_HUMAN,tr|C9J4M6|C9J4M6_HUMAN,tr|C9J2Y9|C9J2Y9_HUMAN" 3 1461.6939 1.38 138128 4411 2 1461.691029 731.8542 DNA-directed RNA polymerase II subunit RPB2 OS=Homo sapiens OX=9606 GN=POLR2B PE=1 SV=1 4.75 1411.2 - 150665 - - - -1.9881 - 1.552 0.466 - 188.4 1 2 0 -0.0029 12 0 0 0 2.18E+06 1.58E+06 - - - 3.6385 1 221125_WJC_METTL3_EV_vs_WT_F10.04417.04417.2 2.10E-10 14/24 R.THSQGGYGSQGYK.Y "sp|Q9Y285|SYFA_HUMAN,tr|K7EPH2|K7EPH2_HUMAN,tr|K7ER00|K7ER00_HUMAN,tr|K7ERS0|K7ERS0_HUMAN" 4 1368.6058 1.29 138132 4417 2 1368.603511 685.3102 Phenylalanine--tRNA ligase alpha subunit OS=Homo sapiens OX=9606 GN=FARSA PE=1 SV=3 8.2 1412 - 472584 - - - -1.7032 - 2.657 0.707 - 558.2 1 2 0 -0.0023 13 0 0 0 5.23E+06 4.06E+06 - - - 6.7702 0.9995 221125_WJC_METTL3_EV_vs_WT_F10.04419.04419.2 0.00032 16-Jul K.EFNAEVHR[166.11]K[136.11].H "sp|P46777|RL5_HUMAN,tr|A0A2R8Y6J3|A0A2R8Y6J3_HUMAN" 2 1146.5901 0.61 138134 4419 2 1146.59111 574.3023 60S ribosomal protein L5 OS=Homo sapiens OX=9606 GN=RPL5 PE=1 SV=3 6.86 1412.3 - 274575 - - - 0.9018 - 1.495 0.412 - 244.9 1 2 0 0.001 9 0 0 0 1.56E+06 2.57E+06 - - - 3.2471 0.9857 221125_WJC_METTL3_EV_vs_WT_F10.04424.04424.3 0.717 Dec-36 R.DKERPVQSLK.T "sp|Q8NEY8|PPHLN_HUMAN,tr|B7Z8L1|B7Z8L1_HUMAN,tr|F8W0Q9|F8W0Q9_HUMAN" 3 1198.667 1.61 138137 4424 3 1198.667248 400.5629 Periphilin-1 OS=Homo sapiens OX=9606 GN=PPHLN1 PE=1 SV=2 8.59 1412.9 - 5.24E+06 - - - 0.2186 - 1.808 0.203 - 165.5 1 2 1 0.0003 10 0 0 0 4.90E+07 3.04E+07 - - - 2.5327 0.9995 221125_WJC_METTL3_EV_vs_WT_F10.04432.04432.3 0.00119 Sep-44 R.C[160.03]AAER[166.11]EEPPEQR[166.11].G sp|Q9GZP4|PITH1_HUMAN 1 1490.6687 1.09 138145 4432 3 1490.668212 497.8968 PITH domain-containing protein 1 OS=Homo sapiens OX=9606 GN=PITHD1 PE=1 SV=1 4.49 1413.8 - 169697 - - - -0.3146 - 1.971 0.413 - 123.4 1 2 1 -0.0005 12 0 0 0 7.63E+05 7.02E+05 - - - 5.0252 0.9978 221125_WJC_METTL3_EV_vs_WT_F10.04437.04437.3 0.0288 Nov-36 R.K[136.11]K[136.11]EEVGVEVK[136.11].L "sp|O94952|FBX21_HUMAN,tr|Q4G104|Q4G104_HUMAN,tr|H0YIE9|H0YIE9_HUMAN,tr|H0YHF6|H0YHF6_HUMAN" 4 1167.6925 0.16 138148 4437 3 1167.693565 390.2381 F-box only protein 21 OS=Homo sapiens OX=9606 GN=FBXO21 PE=2 SV=2 6.23 1414.4 - 1.20E+06 - - - 0.8787 - 1.899 0.312 - 198.4 1 2 1 0.001 10 0 0 0 3.46E+06 2.13E+07 - - - 3.8912 0.9987 221125_WJC_METTL3_EV_vs_WT_F10.04438.04438.2 0.0757 14-Aug R.SEIDNVKK.Q sp|P04264|K2C1_HUMAN 1 931.4975 30.61 138149 4438 2 931.498924 466.756 "Keratin, type II cytoskeletal 1 OS=Homo sapiens OX=9606 GN=KRT1 PE=1 SV=6" 5.79 1414.5 - 1.13E+06 - - - 1.5706 - 1.555 0.306 - 316.1 1 2 0 0.0015 8 0 0 0 7.12E+06 2.33E+05 - - - 2.6321 0.9949 221125_WJC_METTL3_EV_vs_WT_F10.04441.04441.3 0.00326 Nov-36 R.VRESNVLHEK.S "sp|Q9NX62|IMPA3_HUMAN,tr|H0YBS3|H0YBS3_HUMAN" 2 1209.6466 0.95 138152 4441 3 1209.648797 404.2228 "Golgi-resident adenosine 3',5'-bisphosphate 3'-phosphatase OS=Homo sapiens OX=9606 GN=BPNT2 PE=1 SV=1" 6.73 1414.8 - 605018 - - - 1.8286 - 1.89 0.29 - 178 1 2 1 0.0022 10 0 0 0 7.27E+06 7.69E+06 - - - 3.6317 0.9999 221125_WJC_METTL3_EV_vs_WT_F10.04444.04444.3 0.000858 Oct-40 R.RPDQQLQGEGK.L sp|Q8NC51|PAIRB_HUMAN 1 1254.6317 0.83 138155 4444 3 1254.634371 419.2178 Plasminogen activator inhibitor 1 RNA-binding protein OS=Homo sapiens OX=9606 GN=SERBP1 PE=1 SV=2 6.07 1415.2 - 208753 - - - 2.1584 - 2.203 0.433 - 189.6 1 2 0 0.0027 11 0 0 0 1.58E+06 1.92E+06 - - - 5.6105 0.8854 221125_WJC_METTL3_EV_vs_WT_F10.04446.04446.2 0.00697 22-Jun V.GSGGQGPPPPR[166.11]R[166.11].E sp|P48634|PRC2A_HUMAN 1 1181.6168 1.3 138157 4446 2 1181.618335 591.8157 Protein PRRC2A OS=Homo sapiens OX=9606 GN=PRRC2A PE=1 SV=3 12 1415.5 - 127154 - - - 1.2627 - 1.226 0.337 - 42.9 1 1 0 0.0015 12 0 0 0 3.66E+06 2.82E+06 - - - 2.0657 1 221125_WJC_METTL3_EV_vs_WT_F10.04453.04453.3 2.17E-08 16/44 R.QC[160.03]QQNLDAASKR.L "sp|Q9Y6D9|MD1L1_HUMAN,tr|C9JJ38|C9JJ38_HUMAN,tr|C9JIR0|C9JIR0_HUMAN" 3 1417.6732 1.78 138163 4453 3 1417.673935 473.565 Mitotic spindle assembly checkpoint protein MAD1 OS=Homo sapiens OX=9606 GN=MAD1L1 PE=1 SV=2 8.22 1416.4 - 1.08E+06 - - - 0.5107 - 3.027 0.576 - 504.7 1 2 0 0.0007 12 0 0 0 1.47E+07 8.22E+06 - - - 8.0317 0.9988 221125_WJC_METTL3_EV_vs_WT_F10.04454.04454.3 0.0068 Sep-40 K.EPIER[166.11]PEEK[136.11]PK[136.11].K "sp|Q9Y520|PRC2C_HUMAN,tr|E7EPN9|E7EPN9_HUMAN" 2 1376.751 2.14 138164 4454 3 1376.752635 459.9243 Protein PRRC2C OS=Homo sapiens OX=9606 GN=PRRC2C PE=1 SV=4 4.95 1416.5 - 896129 - - - 1.1876 - 1.646 0.3 - 143.1 1 2 0 0.0016 11 0 0 0 2.74E+07 1.28E+07 - - - 3.3 1 221125_WJC_METTL3_EV_vs_WT_F10.04455.04455.3 7.79E-06 18/44 R.QC[160.03]QQNLDAASK[136.11]R[166.11].L "sp|Q9Y6D9|MD1L1_HUMAN,tr|C9JJ38|C9JJ38_HUMAN,tr|C9JIR0|C9JIR0_HUMAN" 3 1435.6957 1.76 138165 4455 3 1435.697891 479.5725 Mitotic spindle assembly checkpoint protein MAD1 OS=Homo sapiens OX=9606 GN=MAD1L1 PE=1 SV=2 8.22 1416.6 - 732842 - - - 1.5393 - 2.693 0.633 - 578 1 2 0 0.0022 12 0 0 0 1.43E+07 8.11E+06 - - - 8.3427 1 221125_WJC_METTL3_EV_vs_WT_F10.04456.04456.3 3.31E-06 Dec-40 R.R[166.11]PDQQLQGEGK[136.11].L sp|Q8NC51|PAIRB_HUMAN 1 1272.6541 0.87 138166 4456 3 1272.655876 425.2253 Plasminogen activator inhibitor 1 RNA-binding protein OS=Homo sapiens OX=9606 GN=SERBP1 PE=1 SV=2 6.07 1416.7 - 694169 - - - 1.3696 - 2.369 0.473 - 313.7 1 2 0 0.0017 11 0 0 0 2.49E+08 2.86E+08 - - - 6.2631 0.9986 221125_WJC_METTL3_EV_vs_WT_F10.04458.04458.3 0.00496 Oct-36 R.VR[166.11]ESNVLHEK[136.11].S "sp|Q9NX62|IMPA3_HUMAN,tr|H0YBS3|H0YBS3_HUMAN" 2 1227.6691 1.14 138168 4458 3 1227.670259 410.2303 "Golgi-resident adenosine 3',5'-bisphosphate 3'-phosphatase OS=Homo sapiens OX=9606 GN=BPNT2 PE=1 SV=1" 6.73 1416.9 - 493856 - - - 0.9807 - 1.784 0.362 - 165.6 1 2 1 0.0012 10 0 0 0 6.94E+06 6.09E+06 - - - 4.2661 1 221125_WJC_METTL3_EV_vs_WT_F10.04462.04462.2 7.95E-08 14/20 R.R[166.11]PDQQLQGEGK[136.11].L sp|Q8NC51|PAIRB_HUMAN 1 1272.6541 0.81 138172 4462 2 1272.658687 637.3343 Plasminogen activator inhibitor 1 RNA-binding protein OS=Homo sapiens OX=9606 GN=SERBP1 PE=1 SV=2 6.07 1417.3 - 131505 - - - 3.5783 - 2.848 0.527 - 678.3 1 2 0 0.0046 11 0 0 0 7.58E+07 9.36E+07 - - - 5.7633 0.9998 221125_WJC_METTL3_EV_vs_WT_F10.04464.04464.2 0.000415 20-Nov R.RPDQQLQGEGK.L sp|Q8NC51|PAIRB_HUMAN 1 1254.6317 0.81 138173 4464 2 1254.629663 628.3231 Plasminogen activator inhibitor 1 RNA-binding protein OS=Homo sapiens OX=9606 GN=SERBP1 PE=1 SV=2 6.07 1417.6 - 61294.8 - - - -1.5941 - 2.405 0.447 - 411.1 1 2 0 -0.002 11 0 0 0 7.58E+07 9.36E+07 - - - 4.7159 0.9844 221125_WJC_METTL3_EV_vs_WT_F10.04466.04466.2 0.111 20-Apr R.SQPQQPSQPQR.T "sp|Q7Z589|EMSY_HUMAN,tr|H0YCS3|H0YCS3_HUMAN,tr|E9PMC9|E9PMC9_HUMAN" 3 1279.6269 1.66 138175 4466 2 1279.627329 640.8207 BRCA2-interacting transcriptional repressor EMSY OS=Homo sapiens OX=9606 GN=EMSY PE=1 SV=2 9.47 1417.9 - 53103.1 - - - 0.3259 - 0.982 0.184 - 61 1 2 0 0.0004 11 0 0 0 3.54E+06 2.13E+06 - - - 0.3508 1 221125_WJC_METTL3_EV_vs_WT_F10.04469.04469.3 6.37E-05 14/52 K.GALTTQDENGQTK[136.11]R[166.11].K "sp|Q9ULX6|AKP8L_HUMAN,tr|A0A7P0T9N5|A0A7P0T9N5_HUMAN,tr|A0A7P0TAD3|A0A7P0TAD3_HUMAN,tr|V9GZ50|V9GZ50_HUMAN,tr|A0A7P0TBP0|A0A7P0TBP0_HUMAN,tr|A0A7P0TAJ5|A0A7P0TAJ5_HUMAN,tr|A0A7P0TAE3|A0A7P0TAE3_HUMAN" 7 1535.7659 0.86 138177 4469 3 1535.766507 512.9292 A-kinase anchor protein 8-like OS=Homo sapiens OX=9606 GN=AKAP8L PE=1 SV=4 6.07 1418.2 - 278212 - - - 0.4161 - 3.079 0.452 - 427.5 1 2 0 0.0006 14 0 0 0 4.24E+06 4.94E+06 - - - 6.5679 0.9811 221125_WJC_METTL3_EV_vs_WT_F10.04473.04473.3 0.056 Aug-32 K.IKELHQQYK.E "sp|O60341|KDM1A_HUMAN,tr|R4GMQ1|R4GMQ1_HUMAN" 2 1185.6506 0.51 138180 4473 3 1185.653243 396.2241 Lysine-specific histone demethylase 1A OS=Homo sapiens OX=9606 GN=KDM1A PE=1 SV=2 8.51 1418.6 - 675476 - - - 2.2233 - 1.643 0.255 - 60.6 1 2 1 0.0026 9 0 0 0 9.41E+06 1.84E+07 - - - 2.8787 0.9932 221125_WJC_METTL3_EV_vs_WT_F10.04477.04477.2 2.16E-05 20-Oct N.NNNNSNNDFQK.R "sp|Q9Y2W1|TR150_HUMAN,tr|A0A3B3ITZ9|A0A3B3ITZ9_HUMAN" 2 1307.5491 3.09 138183 4477 2 1307.548086 654.7818 Thyroid hormone receptor-associated protein 3 OS=Homo sapiens OX=9606 GN=THRAP3 PE=1 SV=2 5.84 1419.1 - 246120 - - - -0.7418 - 1.965 0.577 - 224 1 1 0 -0.001 11 0 0 0 1.27E+07 4.11E+06 - - - 5.1298 1 221125_WJC_METTL3_EV_vs_WT_F10.04486.04486.3 6.18E-08 14/52 K.FGQGVHHTAGQVGK.E sp|Q6UWP8|SBSN_HUMAN 1 1421.7164 1072.88 138190 4486 3 1421.713956 474.9127 Suprabasin OS=Homo sapiens OX=9606 GN=SBSN PE=1 SV=2 8.76 1420.3 - 6.60E+06 - - - -1.7162 - 3.095 0.48 - 129.6 1 2 0 -0.0024 14 0 0 0 5.31E+07 4.95E+04 - - - 6.8933 0.8132 221125_WJC_METTL3_EV_vs_WT_F10.04491.04491.3 0.046 Oct-36 R.SQTEK[136.11]DFSEK[136.11].H "sp|Q8IWL3|HSC20_HUMAN,tr|B0QYH2|B0QYH2_HUMAN" 2 1213.5797 0.82 138194 4491 3 1213.578371 405.5339 Iron-sulfur cluster co-chaperone protein HscB OS=Homo sapiens OX=9606 GN=HSCB PE=1 SV=3 4.68 1420.9 - 552492 - - - -1.1338 - 1.652 0.082 - 128 1 2 1 -0.0014 10 0 0 0 6.85E+06 8.38E+06 - - - 0.9199 0.9998 221125_WJC_METTL3_EV_vs_WT_F10.04492.04492.3 0.00169 Aug-36 R.WASEPEHDHR.K sp|P08574|CY1_HUMAN 1 1262.5428 1.18 138195 4492 3 1262.541235 421.8549 "Cytochrome c1, heme protein, mitochondrial OS=Homo sapiens OX=9606 GN=CYC1 PE=1 SV=3" 5.27 1421 - 471245 - - - -1.2776 - 1.66 0.401 - 136 1 2 0 -0.0016 10 0 0 0 1.09E+07 9.21E+06 - - - 4.4904 1 221125_WJC_METTL3_EV_vs_WT_F10.04493.04493.2 1.63E-05 20-Aug N.NNNNSNNDFQK[136.11].R "sp|Q9Y2W1|TR150_HUMAN,tr|A0A3B3ITZ9|A0A3B3ITZ9_HUMAN" 2 1315.5633 3.09 138196 4493 2 1315.563325 658.7889 Thyroid hormone receptor-associated protein 3 OS=Homo sapiens OX=9606 GN=THRAP3 PE=1 SV=2 5.84 1421.1 - 254076 - - - 0.0524 - 2.049 0.643 - 324 1 1 0 0.0001 11 0 0 0 1.27E+07 4.11E+06 - - - 5.7308 1 221125_WJC_METTL3_EV_vs_WT_F10.04495.04495.2 2.40E-05 15/28 K.SSSSGSVGESSSKGP.R "sp|P13645|K1C10_HUMAN,tr|A0A1B0GVI3|A0A1B0GVI3_HUMAN" 2 1338.5899 999 138197 4495 2 1338.588939 670.3022 "Keratin, type I cytoskeletal 10 OS=Homo sapiens OX=9606 GN=KRT10 PE=1 SV=6" 5.72 1421.4 - 985462 - - - -0.7306 - 3.29 0.611 - 859.8 1 1 1 -0.001 15 0 0 0 1.43E+07 0.00E+00 - - - 6.4814 0.9997 221125_WJC_METTL3_EV_vs_WT_F10.04498.04498.2 3.26E-06 16-Nov R.TGHWLNHGK[136.11].E sp|Q86U44|MTA70_HUMAN 1 1056.5345 0.02 138198 4498 2 1056.533143 529.2745 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 8.47 1421.7 - 1.13E+06 - - - -1.2484 - 2.121 0.345 - 364.3 1 2 0 -0.0013 9 0 0 0 1.59E+08 7.02E+09 - - - 3.764 0.8967 221125_WJC_METTL3_EV_vs_WT_F10.04501.04501.2 1.8 28-Apr R.GQTNNAASASASNST.- "sp|P49841|GSK3B_HUMAN,tr|A0A7I2YQK0|A0A7I2YQK0_HUMAN,tr|A0A3B3ITW1|A0A3B3ITW1_HUMAN" 3 1379.5913 - 138201 4501 2 1379.588371 690.8029 Glycogen synthase kinase-3 beta OS=Homo sapiens OX=9606 GN=GSK3B PE=1 SV=2 5.52 1422 - 324540 - - - -2.1332 - 0.9 0.131 - 39.4 2 2 0 -0.0029 15 0 0 0 - - - - - -0.3859 1 221125_WJC_METTL3_EV_vs_WT_F10.04502.04502.2 2.25E-08 26-Dec R.TPTSGQSVSTC[160.03]SSK[136.11].N "sp|Q32NC0|CR021_HUMAN,tr|L7N2F3|L7N2F3_HUMAN" 2 1433.6548 0.91 138202 4502 2 1433.653446 717.8347 UPF0711 protein C18orf21 OS=Homo sapiens OX=9606 GN=C18orf21 PE=1 SV=1 7.89 1422.2 - 303378 - - - -0.9256 - 2.528 0.651 - 528.3 1 2 0 -0.0013 14 0 0 0 2.33E+06 2.55E+06 - - - 6.1762 0.9999 221125_WJC_METTL3_EV_vs_WT_F10.04507.04507.3 0.00854 Sep-44 R.TK[136.11]PSEDSLSGQK[136.11].G sp|P51116|FXR2_HUMAN 1 1291.6591 1.23 138205 4507 3 1291.657803 431.5603 Fragile X mental retardation syndrome-related protein 2 OS=Homo sapiens OX=9606 GN=FXR2 PE=1 SV=2 5.73 1422.7 - 1.37E+06 - - - -0.9732 - 1.704 0.432 - 99.2 1 2 0 -0.0013 12 0 0 0 7.81E+07 6.34E+07 - - - 4.8334 1 221125_WJC_METTL3_EV_vs_WT_F10.04512.04512.2 1.69E-07 26-Oct R.TPTSGQSVSTC[160.03]SSK.N "sp|Q32NC0|CR021_HUMAN,tr|L7N2F3|L7N2F3_HUMAN" 2 1425.6406 0.9 138210 4512 2 1425.638479 713.8276 UPF0711 protein C18orf21 OS=Homo sapiens OX=9606 GN=C18orf21 PE=1 SV=1 7.89 1423.3 - 286440 - - - -1.4688 - 2.336 0.686 - 346.3 1 2 0 -0.0021 14 0 0 0 2.30E+06 2.55E+06 - - - 6.2363 0.9889 221125_WJC_METTL3_EV_vs_WT_F10.04516.04516.2 0.000159 14-Oct T.GHWLNHGK[136.11].E sp|Q86U44|MTA70_HUMAN 1 955.4868 0.02 138212 4516 2 955.485913 478.7507 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 8.76 1423.8 - 4.14E+06 - - - -0.9105 - 1.892 0.462 - 413.5 1 1 0 -0.0009 8 0 0 0 2.51E+07 1.19E+09 - - - 4.3761 0.979 221125_WJC_METTL3_EV_vs_WT_F10.04520.04520.3 0.00833 Dec-36 R.FHVEEEGKGK.D sp|P00558|PGK1_HUMAN 1 1158.5669 1.29 138215 4520 3 1158.566746 387.1963 Phosphoglycerate kinase 1 OS=Homo sapiens OX=9606 GN=PGK1 PE=1 SV=3 5.5 1424.1 - 974942 - - - -0.1649 - 1.918 0.165 - 184.5 1 2 1 -0.0002 10 0 0 0 1.53E+07 1.18E+07 - - - 2.2816 0.9996 221125_WJC_METTL3_EV_vs_WT_F10.04522.04522.2 0.000461 22-Aug R.TK[136.11]PSEDSLSGQK[136.11].G sp|P51116|FXR2_HUMAN 1 1291.6591 1.43 138217 4522 2 1291.660095 646.8368 Fragile X mental retardation syndrome-related protein 2 OS=Homo sapiens OX=9606 GN=FXR2 PE=1 SV=2 5.73 1424.3 - 201542 - - - 0.8013 - 1.557 0.462 - 109.8 1 2 0 0.001 12 0 0 0 1.68E+07 1.17E+07 - - - 3.618 0.9977 221125_WJC_METTL3_EV_vs_WT_F10.04536.04536.3 0.00553 Aug-44 R.VKTSEDADELHK.L sp|Q9UKX7|NUP50_HUMAN 1 1370.6678 5.46 138228 4536 3 1370.666923 457.8965 Nuclear pore complex protein Nup50 OS=Homo sapiens OX=9606 GN=NUP50 PE=1 SV=2 4.75 1426.2 - 548788 - - - -0.6209 - 1.646 0.351 - 54.4 1 2 1 -0.0009 12 0 0 0 5.20E+06 9.52E+05 - - - 3.8344 0.9999 221125_WJC_METTL3_EV_vs_WT_F10.04543.04543.3 0.00341 15/36 K.KDTGHVYAMK.L sp|Q15208|STK38_HUMAN 1 1148.5648 1.99 138234 4543 3 1148.564851 383.8622 Serine\threonine-protein kinase 38 OS=Homo sapiens OX=9606 GN=STK38 PE=1 SV=1 8.51 1426.8 - 1.36E+06 - - - 0.0192 - 2.612 0.344 - 274.2 1 2 0 0 10 0 0 0 1.43E+07 7.17E+06 - - - 5.1792 0.9836 221125_WJC_METTL3_EV_vs_WT_F10.04549.04549.2 9.60E-06 12-Oct G.HWLNHGK[136.11].E sp|Q86U44|MTA70_HUMAN 1 898.4653 0 138238 4549 2 898.464013 450.2399 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 8.76 1427.5 - 1.77E+07 - - - -1.4547 - 1.945 0.413 - 285.8 1 1 0 -0.0013 7 0 0 0 7.06E+04 5.68E+08 - - - 4.1989 0.9995 221125_WJC_METTL3_EV_vs_WT_F10.04557.04557.3 3.46E-05 13/40 R.QRENPGQSLNR.L sp|P39880|CUX1_HUMAN 1 1297.6487 1.12 138244 4557 3 1297.644543 433.5568 Homeobox protein cut-like 1 OS=Homo sapiens OX=9606 GN=CUX1 PE=1 SV=3 9.6 1428.5 - 1.26E+06 - - - -3.2112 - 2.673 0.485 - 223.8 1 2 1 -0.0042 11 0 0 0 1.60E+08 1.43E+08 - - - 6.7392 0.9905 221125_WJC_METTL3_EV_vs_WT_F10.04563.04563.3 3.66E-05 16/40 R.QR[166.11]ENPGQSLNR[166.11].L sp|P39880|CUX1_HUMAN 1 1317.6653 1.12 138248 4563 3 1317.656122 440.229 Homeobox protein cut-like 1 OS=Homo sapiens OX=9606 GN=CUX1 PE=1 SV=3 9.6 1429.2 - 1.79E+06 - - - -6.9274 - 2.409 0.476 - 375.2 1 2 1 -0.0091 11 0 0 0 1.60E+08 1.43E+08 - - - 6.3421 0.8312 221125_WJC_METTL3_EV_vs_WT_F10.04564.04564.3 1.61 Aug-48 R.LQAQEEQHQEVQK[136.11].A "sp|Q96R06|SPAG5_HUMAN,tr|K7ELG0|K7ELG0_HUMAN" 2 1601.7889 0.88 138249 4564 3 1601.780393 534.9369 Sperm-associated antigen 5 OS=Homo sapiens OX=9606 GN=SPAG5 PE=1 SV=2 4.75 1429.4 - 448389 - - - -5.3097 - 1.528 0.19 - 52 1 2 0 -0.0085 13 0 0 0 8.85E+06 1.00E+07 - - - 1.8054 0.9843 221125_WJC_METTL3_EV_vs_WT_F10.04565.04565.2 0.00298 20-Jul R.QRENPGQSLNR.L sp|P39880|CUX1_HUMAN 1 1297.6487 1.58 138250 4565 2 1297.644988 649.8316 Homeobox protein cut-like 1 OS=Homo sapiens OX=9606 GN=CUX1 PE=1 SV=3 9.6 1429.5 - 456558 - - - -2.8683 - 1.722 0.391 - 53.6 1 2 1 -0.0037 11 0 0 0 2.01E+07 1.27E+07 - - - 3.398 1 221125_WJC_METTL3_EV_vs_WT_F10.04569.04569.4 4.85E-05 14/72 R.ELC[160.03]HTQSSHASLR[166.11].A "sp|Q9P2E9|RRBP1_HUMAN,tr|A0A087WVV2|A0A087WVV2_HUMAN,tr|F8W7S5|F8W7S5_HUMAN" 3 1534.7186 2.39 138252 4569 4 1534.715795 384.6869 Ribosome-binding protein 1 OS=Homo sapiens OX=9606 GN=RRBP1 PE=1 SV=5 7 1430 - 1.24E+06 - - - -1.8238 - 2.747 0.529 - 127.7 1 2 0 -0.0028 13 0 0 0 3.71E+07 1.55E+07 - - - 4.2043 0.9988 221125_WJC_METTL3_EV_vs_WT_F10.04571.04571.3 0.00464 Sep-40 R.DSTHC[160.03]VTTATR.V "sp|P0DP57|SLUR2_HUMAN,tr|H0YB12|H0YB12_HUMAN" 2 1247.5564 3.24 138254 4571 3 1247.552632 416.8594 Secreted Ly-6\uPAR domain-containing protein 2 OS=Homo sapiens OX=9606 GN=SLURP2 PE=1 SV=1 6.74 1430.3 - 682796 - - - -3.0596 - 1.92 0.341 - 96.1 1 2 0 -0.0038 11 0 0 0 1.12E+07 3.47E+06 - - - 4.1939 0.9978 221125_WJC_METTL3_EV_vs_WT_F10.04573.04573.2 0.000214 20-Dec R.QR[166.11]ENPGQSLNR[166.11].L sp|P39880|CUX1_HUMAN 1 1317.6653 1.58 138256 4573 2 1317.662867 659.8399 Homeobox protein cut-like 1 OS=Homo sapiens OX=9606 GN=CUX1 PE=1 SV=3 9.6 1430.6 - 506271 - - - -1.8085 - 2.31 0.517 - 188.5 1 2 1 -0.0024 11 0 0 0 2.01E+07 1.27E+07 - - - 5.1238 0.9974 221125_WJC_METTL3_EV_vs_WT_F10.04578.04578.3 0.00875 Aug-44 R.TKPSEDSLSGQK.G sp|P51116|FXR2_HUMAN 1 1275.6307 1.23 138259 4578 3 1275.626683 426.2175 Fragile X mental retardation syndrome-related protein 2 OS=Homo sapiens OX=9606 GN=FXR2 PE=1 SV=2 5.73 1431.1 - 2.53E+06 - - - -3.1177 - 1.803 0.31 - 75.7 1 2 0 -0.004 12 0 0 0 7.81E+07 6.34E+07 - - - 3.629 0.9882 221125_WJC_METTL3_EV_vs_WT_F10.04590.04590.3 0.451 Sep-36 R.K[136.11]AYLEPEHTK[136.11].A "sp|Q70IA6|MOB2_HUMAN,tr|A0A087WVS8|A0A087WVS8_HUMAN" 2 1230.6579 3.35 138265 4590 3 1230.655195 411.2266 MOB kinase activator 2 OS=Homo sapiens OX=9606 GN=MOB2 PE=1 SV=1 6.76 1432.6 - 3.73E+06 - - - -2.2289 - 1.178 0.282 - 85.2 1 2 0 -0.0027 10 0 0 0 2.71E+08 8.09E+07 - - - 2.1617 0.9984 221125_WJC_METTL3_EV_vs_WT_F10.04591.04591.2 0.00121 22-Aug R.TKPSEDSLSGQK.G sp|P51116|FXR2_HUMAN 1 1275.6307 1.43 138266 4591 2 1275.626842 638.8226 Fragile X mental retardation syndrome-related protein 2 OS=Homo sapiens OX=9606 GN=FXR2 PE=1 SV=2 5.73 1432.7 - 350839 - - - -2.993 - 1.589 0.421 - 110.3 1 2 0 -0.0038 12 0 0 0 1.68E+07 1.17E+07 - - - 3.3678 0.9998 221125_WJC_METTL3_EV_vs_WT_F10.04595.04595.3 0.00173 Nov-36 R.KAYLEPEHTK.A "sp|Q70IA6|MOB2_HUMAN,tr|A0A087WVS8|A0A087WVS8_HUMAN" 2 1214.6295 3.35 138269 4595 3 1214.628009 405.8838 MOB kinase activator 2 OS=Homo sapiens OX=9606 GN=MOB2 PE=1 SV=1 6.76 1433.2 - 1.11E+07 - - - -1.2588 - 2.021 0.385 - 210.8 1 2 0 -0.0015 10 0 0 0 2.71E+08 8.09E+07 - - - 4.8867 0.9997 221125_WJC_METTL3_EV_vs_WT_F10.04602.04602.2 0.227 14-Nov K.RFTDEESR.V "sp|Q9NYF8|BCLF1_HUMAN,tr|H0YF00|H0YF00_HUMAN,tr|E9PKI6|E9PKI6_HUMAN,tr|A0A1W2PQ43|A0A1W2PQ43_HUMAN,tr|E9PK91|E9PK91_HUMAN,tr|E9PK09|E9PK09_HUMAN,tr|E9PQN2|E9PQN2_HUMAN" 7 1038.473 999 138275 4602 2 1038.472006 520.2438 Bcl-2-associated transcription factor 1 OS=Homo sapiens OX=9606 GN=BCLAF1 PE=1 SV=2 4.68 1433.8 - 672641 - - - -0.9928 - 1.846 0.407 - 313.8 1 2 0 -0.001 8 0 0 0 7.11E+06 0.00E+00 - - - 3.8956 0.9998 221125_WJC_METTL3_EV_vs_WT_F10.04610.04610.2 0.00108 16-Nov R.TGHWLNHGK.E sp|Q86U44|MTA70_HUMAN 1 1048.5203 0.02 138282 4610 2 1048.519782 525.2674 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 8.47 1434.8 - 2.35E+06 - - - -0.4578 - 1.926 0.405 - 377.7 1 2 0 -0.0005 9 0 0 0 1.60E+08 7.07E+09 - - - 3.9284 1 221125_WJC_METTL3_EV_vs_WT_F10.04613.04613.3 4.91E-08 17/64 R.AGEGR[166.11]PNGEGAEPGPGR[166.11].S sp|Q9P2Y4|ZN219_HUMAN 1 1626.7613 1.34 138284 4613 3 1626.758132 543.2611 Zinc finger protein 219 OS=Homo sapiens OX=9606 GN=ZNF219 PE=1 SV=2 4.79 1435.2 - 408783 - - - -1.9689 - 3.661 0.611 - 229.5 1 2 0 -0.0032 17 0 0 0 9.76E+06 7.29E+06 - - - 8.6296 0.9977 221125_WJC_METTL3_EV_vs_WT_F10.04616.04616.2 0.00037 13/24 K.LQASNVTNK[136.11]NDPK[136.11].S "sp|Q9UKM9|RALY_HUMAN,tr|Q5QPM0|Q5QPM0_HUMAN,tr|Q5QPM2|Q5QPM2_HUMAN,tr|Q5QPM1|Q5QPM1_HUMAN,tr|Q5QPL9|Q5QPL9_HUMAN" 5 1443.7653 1.33 138287 4616 2 1443.766272 722.8899 RNA-binding protein Raly OS=Homo sapiens OX=9606 GN=RALY PE=1 SV=1 8.59 1435.6 - 276821 - - - 0.7037 - 2.304 0.416 - 363 1 2 1 0.001 13 0 0 0 1.06E+07 7.97E+06 - - - 4.2554 1 221125_WJC_METTL3_EV_vs_WT_F10.04619.04619.3 6.38E-07 15/60 K.AAGPSLSHTSGGTQSK.V sp|P27694|RFA1_HUMAN 1 1484.7219 1.23 138288 4619 3 1484.719867 495.9146 Replication protein A 70 kDa DNA-binding subunit OS=Homo sapiens OX=9606 GN=RPA1 PE=1 SV=2 8.8 1436 - 3.37E+06 - - - -1.3929 - 3.034 0.566 - 325.8 1 2 0 -0.0021 16 0 0 0 5.86E+07 4.77E+07 - - - 7.6976 1 221125_WJC_METTL3_EV_vs_WT_F10.04623.04623.3 8.76E-10 24/64 R.AGEGRPNGEGAEPGPGR.S sp|Q9P2Y4|ZN219_HUMAN 1 1606.7448 1.34 138292 4623 3 1606.743378 536.5889 Zinc finger protein 219 OS=Homo sapiens OX=9606 GN=ZNF219 PE=1 SV=2 4.79 1436.4 - 739396 - - - -0.8819 - 4.192 0.617 - 591.3 1 2 0 -0.0014 17 0 0 0 9.76E+06 7.29E+06 - - - 9.0392 0.9528 221125_WJC_METTL3_EV_vs_WT_F10.04627.04627.2 0.092 18-Jul K.NLHSEISGKR.D sp|P15924|DESP_HUMAN 1 1139.6047 999 138296 4627 2 1139.599736 570.8096 Desmoplakin OS=Homo sapiens OX=9606 GN=DSP PE=1 SV=3 8.75 1436.9 - 267355 - - - -4.3734 - 1.305 0.2 - 147.3 1 2 0 -0.005 10 0 0 0 6.37E+06 0.00E+00 - - - 1.2597 0.9992 221125_WJC_METTL3_EV_vs_WT_F10.04630.04630.3 0.0455 Aug-48 K.TATPQQAQEVHEK.L "sp|P60174|TPIS_HUMAN,tr|U3KPZ0|U3KPZ0_HUMAN" 2 1465.7161 1.37 138297 4630 3 1465.71742 489.5793 Triosephosphate isomerase OS=Homo sapiens OX=9606 GN=TPI1 PE=1 SV=4 5.37 1437.3 - 938723 - - - 0.8863 - 1.806 0.299 - 74.9 1 2 0 0.0013 13 0 0 0 1.02E+08 7.46E+07 - - - 3.4759 0.9999 221125_WJC_METTL3_EV_vs_WT_F10.04641.04641.3 8.10E-06 14/48 K.TATPQQAQEVHEK[136.11].L "sp|P60174|TPIS_HUMAN,tr|U3KPZ0|U3KPZ0_HUMAN" 2 1473.7303 1.37 138305 4641 3 1473.727772 492.2507 Triosephosphate isomerase OS=Homo sapiens OX=9606 GN=TPI1 PE=1 SV=4 5.37 1438.6 - 1.45E+06 - - - -1.7296 - 2.29 0.447 - 251.3 1 2 0 -0.0025 13 0 0 0 1.02E+08 7.44E+07 - - - 5.7693 1 221125_WJC_METTL3_EV_vs_WT_F10.04647.04647.3 0.0179 Nov-32 R.RPAEIYHC[160.03]R.R "sp|Q9NWU5|RM22_HUMAN,tr|E7ESL0|E7ESL0_HUMAN,tr|J3KQY1|J3KQY1_HUMAN" 3 1200.5822 0.98 138309 4647 3 1200.580036 401.2013 "39S ribosomal protein L22, mitochondrial OS=Homo sapiens OX=9606 GN=MRPL22 PE=1 SV=1" 8.23 1439.4 - 621354 - - - -1.8116 - 2.358 0.485 - 185.9 1 2 0 -0.0022 9 0 0 0 1.30E+07 1.33E+07 - - - 6.5319 0.9999 221125_WJC_METTL3_EV_vs_WT_F10.04655.04655.3 0.000149 Nov-32 R.R[166.11]PAEIYHC[160.03]R[166.11].R "sp|Q9NWU5|RM22_HUMAN,tr|E7ESL0|E7ESL0_HUMAN,tr|J3KQY1|J3KQY1_HUMAN" 3 1220.5988 1.59 138314 4655 3 1220.597669 407.8735 "39S ribosomal protein L22, mitochondrial OS=Homo sapiens OX=9606 GN=MRPL22 PE=1 SV=1" 8.23 1440.4 - 1.08E+06 - - - -0.8865 - 2.157 0.44 - 270.6 1 2 0 -0.0011 9 0 0 0 2.19E+07 1.38E+07 - - - 5.762 1 221125_WJC_METTL3_EV_vs_WT_F10.04658.04658.2 1.22E-05 14/24 K.GSQITQQSTNQSR[166.11].N sp|P50750|CDK9_HUMAN 1 1443.6942 0.66 138317 4658 2 1443.692793 722.8544 Cyclin-dependent kinase 9 OS=Homo sapiens OX=9606 GN=CDK9 PE=1 SV=3 9.75 1440.7 - 351453 - - - -0.942 - 2.945 0.575 - 715.7 1 2 0 -0.0014 13 0 0 0 2.56E+06 3.86E+06 - - - 6.0597 1 221125_WJC_METTL3_EV_vs_WT_F10.04660.04660.2 2.07E-07 24-Nov K.GSQITQQSTNQSR.N sp|P50750|CDK9_HUMAN 1 1433.6859 0.66 138319 4660 2 1433.688687 717.8502 Cyclin-dependent kinase 9 OS=Homo sapiens OX=9606 GN=CDK9 PE=1 SV=3 9.75 1441 - 187675 - - - 1.9558 - 2.398 0.617 - 376.1 1 2 0 0.0028 13 0 0 0 2.56E+06 3.86E+06 - - - 5.8421 0.9726 221125_WJC_METTL3_EV_vs_WT_F10.04664.04664.3 0.000482 Oct-44 F.LNTPSDKSEDGR.L "sp|Q9BUB7|TMM70_HUMAN,tr|D4PHA6|D4PHA6_HUMAN" 2 1317.6161 0.13 138321 4664 3 1317.615957 440.2126 "Transmembrane protein 70, mitochondrial OS=Homo sapiens OX=9606 GN=TMEM70 PE=1 SV=2" 4.56 1441.5 - 489773 - - - -0.088 - 2.084 0.463 - 109 1 1 1 -0.0001 12 0 0 0 1.56E+07 1.22E+08 - - - 5.7373 0.9999 221125_WJC_METTL3_EV_vs_WT_F10.04666.04666.2 2.27E-06 24-Sep K.TATPQQAQEVHEK.L "sp|P60174|TPIS_HUMAN,tr|U3KPZ0|U3KPZ0_HUMAN" 2 1465.7161 1.44 138323 4666 2 1465.715481 733.8653 Triosephosphate isomerase OS=Homo sapiens OX=9606 GN=TPI1 PE=1 SV=4 5.37 1441.7 - 251094 - - - -0.4366 - 1.986 0.553 - 228.3 1 2 0 -0.0006 13 0 0 0 3.43E+06 2.38E+06 - - - 4.8862 0.9999 221125_WJC_METTL3_EV_vs_WT_F10.04668.04668.2 2.80E-06 24-Oct K.TATPQQAQEVHEK[136.11].L "sp|P60174|TPIS_HUMAN,tr|U3KPZ0|U3KPZ0_HUMAN" 2 1473.7303 1.44 138325 4668 2 1473.728684 737.8724 Triosephosphate isomerase OS=Homo sapiens OX=9606 GN=TPI1 PE=1 SV=4 5.37 1442 - 206227 - - - -1.1108 - 2.111 0.585 - 335.2 1 2 0 -0.0016 13 0 0 0 3.43E+06 2.38E+06 - - - 5.2789 0.989 221125_WJC_METTL3_EV_vs_WT_F10.04671.04671.2 6.49E-05 20-Oct A.TPQQAQEVHEK.L "sp|P60174|TPIS_HUMAN,tr|U3KPZ0|U3KPZ0_HUMAN" 2 1293.6313 1.41 138328 4671 2 1293.631411 647.8229 Triosephosphate isomerase OS=Homo sapiens OX=9606 GN=TPI1 PE=1 SV=4 5.37 1442.4 - 59382.7 - - - 0.0634 - 1.765 0.489 - 322.1 1 1 0 0.0001 11 0 0 0 6.73E+05 4.78E+05 - - - 4.1897 0.9998 221125_WJC_METTL3_EV_vs_WT_F10.04677.04677.3 0.000467 13/44 K.KAPKEDVDAAVK.Q "sp|P07814|SYEP_HUMAN,tr|V9GYZ6|V9GYZ6_HUMAN" 2 1269.6929 1.1 138332 4677 3 1269.693711 424.2382 Bifunctional glutamate\proline--tRNA ligase OS=Homo sapiens OX=9606 GN=EPRS1 PE=1 SV=5 6.12 1443 - 874456 - - - 0.6655 - 2.524 0.457 - 173.8 1 2 1 0.0008 12 0 0 0 1.80E+07 1.63E+07 - - - 6.2012 0.8748 221125_WJC_METTL3_EV_vs_WT_F10.04679.04679.3 0.0216 Sep-44 K.IQDTNVTSEDKK.F "sp|Q9H6D7|HAUS4_HUMAN,tr|H0YJ09|H0YJ09_HUMAN,tr|G3V4X7|G3V4X7_HUMAN,tr|G3V5A5|G3V5A5_HUMAN,tr|G3V541|G3V541_HUMAN,tr|H0YIZ6|H0YIZ6_HUMAN,tr|G3V5Z2|G3V5Z2_HUMAN" 7 1376.6783 3.62 138334 4679 3 1376.678996 459.9001 HAUS augmin-like complex subunit 4 OS=Homo sapiens OX=9606 GN=HAUS4 PE=1 SV=1 4.56 1443.2 - 646644 - - - 0.478 - 1.367 0.081 - 108.9 1 2 0 0.0007 12 0 0 0 1.85E+07 5.11E+06 - - - 0.3094 0.9883 221125_WJC_METTL3_EV_vs_WT_F10.04684.04684.2 0.000148 20-Sep A.TPQQAQEVHEK[136.11].L "sp|P60174|TPIS_HUMAN,tr|U3KPZ0|U3KPZ0_HUMAN" 2 1301.6455 1.41 138339 4684 2 1301.646174 651.83 Triosephosphate isomerase OS=Homo sapiens OX=9606 GN=TPI1 PE=1 SV=4 5.37 1443.8 - 75729 - - - 0.4955 - 1.916 0.463 - 335.7 1 1 0 0.0006 11 0 0 0 6.73E+05 4.78E+05 - - - 4.2196 0.9999 221125_WJC_METTL3_EV_vs_WT_F10.04690.04690.3 8.27E-07 13/44 K.K[136.11]APK[136.11]EDVDAAVK[136.11].Q "sp|P07814|SYEP_HUMAN,tr|V9GYZ6|V9GYZ6_HUMAN" 2 1293.7355 1.1 138343 4690 3 1293.735765 432.2524 Bifunctional glutamate\proline--tRNA ligase OS=Homo sapiens OX=9606 GN=EPRS1 PE=1 SV=5 6.12 1444.5 - 1.44E+06 - - - 0.2311 - 2.777 0.569 - 209 1 2 1 0.0003 12 0 0 0 1.80E+07 1.63E+07 - - - 7.7148 0.9999 221125_WJC_METTL3_EV_vs_WT_F10.04694.04694.2 7.38E-06 22-Nov R.GSGSGQSPSYGR.H sp|Q86YZ3|HORN_HUMAN 1 1138.5003 999 138347 4694 2 1138.500919 570.2574 Hornerin OS=Homo sapiens OX=9606 GN=HRNR PE=1 SV=2 8.75 1444.8 - 357450 - - - 0.5314 - 2.113 0.596 - 377.9 1 2 0 0.0006 12 0 0 0 1.93E+06 0.00E+00 - - - 5.4113 0.9989 221125_WJC_METTL3_EV_vs_WT_F10.04695.04695.2 0.00291 20-Sep K.HGSGTQYVSTR[166.11].Q sp|Q96B23|CR025_HUMAN 1 1201.5715 0.54 138348 4695 2 1201.569154 601.793 Uncharacterized protein C18orf25 OS=Homo sapiens OX=9606 GN=C18orf25 PE=1 SV=3 8.75 1444.9 - 331173 - - - -1.9683 - 1.257 0.45 - 141.6 1 2 0 -0.0024 11 0 0 0 8.31E+05 1.53E+06 - - - 2.9827 0.9988 221125_WJC_METTL3_EV_vs_WT_F10.04696.04696.3 0.014 Aug-40 K.HGSGTQYVSTR.Q sp|Q96B23|CR025_HUMAN 1 1191.5632 0.39 138349 4696 3 1191.562416 398.195 Uncharacterized protein C18orf25 OS=Homo sapiens OX=9606 GN=C18orf25 PE=1 SV=3 8.75 1445.1 - 288782 - - - -0.6991 - 1.598 0.296 - 72.3 1 2 0 -0.0008 11 0 0 0 3.57E+06 9.07E+06 - - - 3.1715 0.9988 221125_WJC_METTL3_EV_vs_WT_F10.04699.04699.3 0.00969 Nov-52 K.NQTAEK[136.11]EEFEHQQK[136.11].E "sp|P11142|HSP7C_HUMAN,tr|E9PNE6|E9PNE6_HUMAN,tr|A8K7Q2|A8K7Q2_HUMAN,tr|E9PKE3|E9PKE3_HUMAN,tr|E9PM13|E9PM13_HUMAN,tr|E9PS65|E9PS65_HUMAN" 6 1760.83 0.001 138352 4699 3 1760.82948 587.9506 Heat shock cognate 71 kDa protein OS=Homo sapiens OX=9606 GN=HSPA8 PE=1 SV=1 4.91 1445.5 - 170562 - - - -0.3192 - 1.747 0.389 - 105 1 2 1 -0.0006 14 0 0 0 0.00E+00 4.13E+06 - - - 4.3594 1 221125_WJC_METTL3_EV_vs_WT_F10.04712.04712.3 5.20E-09 19/40 K.R[166.11]FEEGVGK[136.11]PAK[136.11].Q sp|Q8IYI6|EXOC8_HUMAN 1 1242.6931 1.29 138361 4712 3 1242.692462 415.2383 Exocyst complex component 8 OS=Homo sapiens OX=9606 GN=EXOC8 PE=1 SV=2 8.59 1446.9 - 2.11E+06 - - - -0.5062 - 2.917 0.427 - 743.8 1 2 0 -0.0006 11 0 0 0 4.45E+07 3.44E+07 - - - 6.3417 1 221125_WJC_METTL3_EV_vs_WT_F10.04720.04720.3 2.97E-06 23/56 K.EEASGSSVTAEEAKK.F sp|P13010|XRCC5_HUMAN 1 1521.7158 1.14 138366 4720 3 1521.722607 508.2459 X-ray repair cross-complementing protein 5 OS=Homo sapiens OX=9606 GN=XRCC5 PE=1 SV=3 4.49 1447.9 - 1.27E+06 - - - 4.443 - 4 0.608 - 879.1 1 2 0 0.0068 15 0 0 0 2.81E+08 2.47E+08 - - - 8.9341 1 221125_WJC_METTL3_EV_vs_WT_F10.04726.04726.3 5.95E-10 19/56 K.EEASGSSVTAEEAK[136.11]K[136.11].F sp|P13010|XRCC5_HUMAN 1 1537.7442 1.14 138368 4726 3 1537.742526 513.5887 X-ray repair cross-complementing protein 5 OS=Homo sapiens OX=9606 GN=XRCC5 PE=1 SV=3 4.49 1448.6 - 3.90E+06 - - - -1.1185 - 3.669 0.667 - 533.2 1 2 0 -0.0017 15 0 0 0 2.81E+08 2.47E+08 - - - 9.3679 1 221125_WJC_METTL3_EV_vs_WT_F10.04733.04733.2 6.68E-10 13/28 K.GTSSSSATVSDDTEK[136.11].K "sp|Q86UP3|ZFHX4_HUMAN,tr|E5RI93|E5RI93_HUMAN,tr|E7EVZ1|E7EVZ1_HUMAN" 3 1478.6464 2.07 138371 4733 2 1478.642097 740.3305 Zinc finger homeobox protein 4 OS=Homo sapiens OX=9606 GN=ZFHX4 PE=1 SV=1 4.03 1449.4 - 1.03E+06 - - - -2.8939 - 3.047 0.569 - 669.4 1 2 0 -0.0043 15 0 0 0 1.62E+07 7.83E+06 - - - 5.9815 0.9479 221125_WJC_METTL3_EV_vs_WT_F10.04737.04737.3 0.0339 Jul-40 K.LGIHEDSTNRR.R sp|P08238|HS90B_HUMAN 1 1296.6535 0.78 138373 4737 3 1296.647836 433.2251 Heat shock protein HSP 90-beta OS=Homo sapiens OX=9606 GN=HSP90AB1 PE=1 SV=4 6.75 1449.9 - 1.63E+06 - - - -4.3381 - 1.495 0.224 - 75.7 1 2 0 -0.0056 11 0 0 0 4.63E+07 5.93E+07 - - - 2.1782 0.9928 221125_WJC_METTL3_EV_vs_WT_F10.04744.04744.3 0.000165 23/48 R.LSAKPAPPKPEPK.P "sp|P05204|HMGN2_HUMAN,sp|Q15651|HMGN3_HUMAN,tr|A0A087WZE9|A0A087WZE9_HUMAN" 3 1358.7922 0.78 138375 4744 3 1358.790374 453.938 Non-histone chromosomal protein HMG-17 OS=Homo sapiens OX=9606 GN=HMGN2 PE=1 SV=3 9.7 1450.8 - 3.47E+06 - - - -1.3335 - 3.038 0.375 - 578.9 1 1 0 -0.0018 13 0 0 0 1.35E+08 1.74E+08 - - - 5.7332 0.9998 221125_WJC_METTL3_EV_vs_WT_F10.04746.04746.2 0.00243 13/28 K.EEASGSSVTAEEAKK.F sp|P13010|XRCC5_HUMAN 1 1521.7158 1.19 138377 4746 2 1521.712776 761.8652 X-ray repair cross-complementing protein 5 OS=Homo sapiens OX=9606 GN=XRCC5 PE=1 SV=3 4.49 1451 - 1.11E+06 - - - -2.0175 - 2.509 0.541 - 324.6 1 2 0 -0.0031 15 0 0 0 2.22E+07 1.87E+07 - - - 5.2974 1 221125_WJC_METTL3_EV_vs_WT_F10.04749.04749.2 2.33E-10 16/28 K.EEASGSSVTAEEAK[136.11]K[136.11].F sp|P13010|XRCC5_HUMAN 1 1537.7442 1.19 138378 4749 2 1537.739572 769.8794 X-ray repair cross-complementing protein 5 OS=Homo sapiens OX=9606 GN=XRCC5 PE=1 SV=3 4.49 1451.4 - 1.22E+06 - - - -3.0395 - 3.298 0.681 - 1184.8 1 2 0 -0.0047 15 0 0 0 2.22E+07 1.87E+07 - - - 7.0032 0.9991 221125_WJC_METTL3_EV_vs_WT_F10.04753.04753.2 1.17E-06 16-Oct R.TGHWLNHGK[136.11].E sp|Q86U44|MTA70_HUMAN 1 1056.5345 0.01 138379 4753 2 1056.532121 529.2745 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 8.47 1451.8 - 2.18E+07 - - - -2.2157 - 2.051 0.309 - 301.7 1 2 0 -0.0023 9 0 0 0 1.09E+07 8.76E+08 - - - 3.4007 0.9983 221125_WJC_METTL3_EV_vs_WT_F10.04754.04754.3 0.00351 19/48 R.LSAK[136.11]PAPPK[136.11]PEPK[136.11].P "sp|P05204|HMGN2_HUMAN,sp|Q15651|HMGN3_HUMAN,tr|A0A087WZE9|A0A087WZE9_HUMAN" 3 1382.8348 0.78 138380 4754 3 1382.833795 461.9522 Non-histone chromosomal protein HMG-17 OS=Homo sapiens OX=9606 GN=HMGN2 PE=1 SV=3 9.7 1451.9 - 6.50E+06 - - - -0.7166 - 3.044 0.519 - 427.5 1 1 0 -0.001 13 0 0 0 1.35E+08 1.74E+08 - - - 7.3442 1 221125_WJC_METTL3_EV_vs_WT_F10.04759.04759.3 1.24E-09 17/52 R.GADQKPTSADC[160.03]AVR.A "sp|Q8IX01|SUGP2_HUMAN,tr|M0R2Z9|M0R2Z9_HUMAN,tr|M0R3F6|M0R3F6_HUMAN" 3 1474.6834 1.07 138382 4759 3 1474.677424 492.5684 SURP and G-patch domain-containing protein 2 OS=Homo sapiens OX=9606 GN=SUGP2 PE=1 SV=2 5.95 1452.5 - 3.23E+06 - - - -4.0802 - 3.199 0.675 - 483.6 1 2 0 -0.006 14 0 0 0 3.01E+07 2.81E+07 - - - 9.1542 0.9996 221125_WJC_METTL3_EV_vs_WT_F10.04767.04767.3 0.0731 28-Dec R.DR[166.11]HDDYYR[166.11].E "sp|Q16630|CPSF6_HUMAN,tr|F8WJN3|F8WJN3_HUMAN" 2 1158.4957 0.47 138388 4767 3 1158.494863 387.1725 Cleavage and polyadenylation specificity factor subunit 6 OS=Homo sapiens OX=9606 GN=CPSF6 PE=1 SV=2 5.3 1453.5 - 1.30E+06 - - - -0.7441 - 2.42 0.371 - 328.9 1 2 1 -0.0009 8 0 0 0 5.28E+06 1.12E+07 - - - 5.4383 1 221125_WJC_METTL3_EV_vs_WT_F10.04770.04770.3 1.07E-07 17/52 K.SNEEGSEEKGPEVR.E sp|P31947|1433S_HUMAN 1 1545.6907 999 138391 4770 3 1545.688811 516.2375 14-3-3 protein sigma OS=Homo sapiens OX=9606 GN=SFN PE=1 SV=1 4.32 1453.9 - 710932 - - - -1.2182 - 3.525 0.641 - 411.1 1 2 1 -0.0019 14 0 0 0 8.90E+07 0.00E+00 - - - 9.0342 1 221125_WJC_METTL3_EV_vs_WT_F10.04776.04776.3 2.30E-05 14/36 K.K[136.11]DDAITAYK[136.11]K[136.11].Y "sp|Q9BY77|PDIP3_HUMAN,tr|F6VRR5|F6VRR5_HUMAN" 2 1175.6612 1.45 138396 4776 3 1175.661483 392.8944 Polymerase delta-interacting protein 3 OS=Homo sapiens OX=9606 GN=POLDIP3 PE=1 SV=2 8.43 1454.6 - 960061 - - - 0.2075 - 2.966 0.496 - 363.6 1 2 0 0.0002 10 0 0 0 5.29E+08 3.64E+08 - - - 7.245 0.9999 221125_WJC_METTL3_EV_vs_WT_F10.04781.04781.2 0.00272 22-Sep K.HDVTC[160.03]TVSGGGR.S sp|P82933|RT09_HUMAN 1 1244.5568 1.09 138401 4781 2 1244.55681 623.2857 "28S ribosomal protein S9, mitochondrial OS=Homo sapiens OX=9606 GN=MRPS9 PE=1 SV=2" 6.74 1455.3 - 154673 - - - 0.0209 - 1.709 0.55 - 173 1 2 0 0 12 0 0 0 6.64E+06 6.10E+06 - - - 4.5134 1 221125_WJC_METTL3_EV_vs_WT_F10.04785.04785.3 0.00107 Dec-36 K.KDDAITAYKK.Y "sp|Q9BY77|PDIP3_HUMAN,tr|F6VRR5|F6VRR5_HUMAN" 2 1151.6186 1.45 138403 4785 3 1151.618512 384.8802 Polymerase delta-interacting protein 3 OS=Homo sapiens OX=9606 GN=POLDIP3 PE=1 SV=2 8.43 1455.8 - 3.58E+06 - - - -0.1103 - 2.378 0.52 - 283.1 1 2 0 -0.0001 10 0 0 0 5.29E+08 3.64E+08 - - - 6.8673 1 221125_WJC_METTL3_EV_vs_WT_F10.04786.04786.3 9.78E-06 15/40 K.HLNNEHALDDR.S "sp|O15409|FOXP2_HUMAN,tr|Q0PRL4|Q0PRL4_HUMAN,tr|Q8N6B5|Q8N6B5_HUMAN,tr|A0A0U1RQE0|A0A0U1RQE0_HUMAN,tr|A0A0U1RQR8|A0A0U1RQR8_HUMAN,tr|A8MUV4|A8MUV4_HUMAN,tr|A0A0U1RQM2|A0A0U1RQM2_HUMAN,tr|A0A0U1RQY3|A0A0U1RQY3_HUMAN,tr|A0A0U1RQE6|A0A0U1RQE6_HUMAN" 9 1332.6171 8.51 138404 4786 3 1332.616428 445.213 Forkhead box protein P2 OS=Homo sapiens OX=9606 GN=FOXP2 PE=1 SV=2 5.21 1455.9 - 1.78E+06 - - - -0.4863 - 2.529 0.515 - 263.4 1 2 0 -0.0006 11 0 0 0 3.26E+07 3.83E+06 - - - 6.9174 1 221125_WJC_METTL3_EV_vs_WT_F10.04788.04788.3 0.0046 Dec-44 K.HDVTC[160.03]TVSGGGR[166.11].S sp|P82933|RT09_HUMAN 1 1254.5651 0.9 138406 4788 3 1254.565721 419.1956 "28S ribosomal protein S9, mitochondrial OS=Homo sapiens OX=9606 GN=MRPS9 PE=1 SV=2" 6.74 1456.1 - 627400 - - - 0.5317 - 2.253 0.469 - 208.6 1 2 0 0.0007 12 0 0 0 6.39E+06 7.07E+06 - - - 6.0202 0.9999 221125_WJC_METTL3_EV_vs_WT_F10.04789.04789.3 6.51E-05 16/44 K.KPHVVTVAGENR.D sp|Q7KZ85|SPT6H_HUMAN 1 1305.7153 1.23 138407 4789 3 1305.715173 436.2457 Transcription elongation factor SPT6 OS=Homo sapiens OX=9606 GN=SUPT6H PE=1 SV=2 8.75 1456.2 - 604970 - - - -0.1225 - 2.726 0.39 - 449.5 1 2 0 -0.0002 12 0 0 0 3.17E+06 2.58E+06 - - - 5.6678 1 221125_WJC_METTL3_EV_vs_WT_F10.04790.04790.2 4.88E-07 13/22 K.HDVTC[160.03]TVSGGGR[166.11].S sp|P82933|RT09_HUMAN 1 1254.5651 1.09 138408 4790 2 1254.566344 628.2898 "28S ribosomal protein S9, mitochondrial OS=Homo sapiens OX=9606 GN=MRPS9 PE=1 SV=2" 6.74 1456.3 - 512810 - - - 1.0282 - 2.689 0.654 - 457.1 1 2 0 0.0013 12 0 0 0 6.64E+06 6.10E+06 - - - 6.4737 1 221125_WJC_METTL3_EV_vs_WT_F10.04792.04792.3 1.25E-05 14/44 K.K[136.11]PHVVTVAGENR[166.11].D sp|Q7KZ85|SPT6H_HUMAN 1 1323.7378 1.15 138410 4792 3 1323.737222 442.2532 Transcription elongation factor SPT6 OS=Homo sapiens OX=9606 GN=SUPT6H PE=1 SV=2 8.75 1456.6 - 483690 - - - -0.4389 - 2.438 0.478 - 325.7 1 2 0 -0.0006 12 0 0 0 3.24E+06 2.82E+06 - - - 6.3393 0.9947 221125_WJC_METTL3_EV_vs_WT_F10.04797.04797.2 1.44E-06 24-Nov L.SSSQFSSGSQSSR.D sp|P02533|K1C14_HUMAN 1 1330.5749 2.21 138415 4797 2 1330.575254 666.2947 "Keratin, type I cytoskeletal 14 OS=Homo sapiens OX=9606 GN=KRT14 PE=1 SV=4" 9.47 1457.2 - 282694 - - - 0.239 - 2.249 0.602 - 393.9 1 1 0 0.0003 13 0 0 0 1.47E+06 6.66E+05 - - - 5.5674 0.9999 221125_WJC_METTL3_EV_vs_WT_F10.04798.04798.3 1.76E-05 Nov-52 R.AGTEDEEEEEEGRR.E "sp|O95456|PSMG1_HUMAN,tr|F8WBH7|F8WBH7_HUMAN" 2 1634.6656 0.66 138416 4798 3 1634.664986 545.8958 Proteasome assembly chaperone 1 OS=Homo sapiens OX=9606 GN=PSMG1 PE=1 SV=1 3.99 1457.3 - 246950 - - - -0.3768 - 2.085 0.437 - 175.7 1 2 0 -0.0006 14 0 0 0 8.41E+05 1.27E+06 - - - 5.3646 0.9999 221125_WJC_METTL3_EV_vs_WT_F10.04800.04800.3 0.000576 Nov-36 K.K[136.11]DDAITAYKK[136.11].Y "sp|Q9BY77|PDIP3_HUMAN,tr|F6VRR5|F6VRR5_HUMAN" 2 1167.647 - 138418 4800 3 1167.647439 390.223 Polymerase delta-interacting protein 3 OS=Homo sapiens OX=9606 GN=POLDIP3 PE=1 SV=2 8.43 1457.6 - 179724 - - - 0.3426 - 2.218 0.447 - 161.7 1 2 0 0.0004 10 0 0 0 - - - - - 5.8499 0.9999 221125_WJC_METTL3_EV_vs_WT_F10.04802.04802.2 0.000197 24-Jul R.EENTSNESTDVTK.G "sp|Q09472|EP300_HUMAN,tr|A0A669KB12|A0A669KB12_HUMAN" 2 1452.6216 2.26 138420 4802 2 1452.621091 727.3181 Histone acetyltransferase p300 OS=Homo sapiens OX=9606 GN=EP300 PE=1 SV=2 4 1457.9 - 139813 - - - -0.358 - 1.511 0.645 - 99.1 1 2 0 -0.0005 13 0 0 0 2.83E+06 1.25E+06 - - - 4.8642 1 221125_WJC_METTL3_EV_vs_WT_F10.04804.04804.2 2.82E-08 30-Oct R.LTDSSPSSTSTSNSQR.L sp|Q5VT06|CE350_HUMAN 1 1653.7442 1.8 138422 4804 2 1653.744788 827.8794 Centrosome-associated protein 350 OS=Homo sapiens OX=9606 GN=CEP350 PE=1 SV=1 5.84 1458.1 - 66994.7 - - - 0.364 - 2.547 0.717 - 187.6 1 2 0 0.0006 16 0 0 0 4.50E+06 2.50E+06 - - - 6.6351 0.9872 221125_WJC_METTL3_EV_vs_WT_F10.04806.04806.2 0.000267 12-Oct G.HWLNHGK[136.11].E sp|Q86U44|MTA70_HUMAN 1 898.4653 0.01 138423 4806 2 898.46603 450.2399 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 8.76 1458.3 - 2.02E+06 - - - 0.7902 - 2.065 0.393 - 283 1 1 0 0.0007 7 0 0 0 1.21E+05 2.10E+07 - - - 4.2411 0.9916 221125_WJC_METTL3_EV_vs_WT_F10.04808.04808.2 0.000475 14-Oct T.GHWLNHGK[136.11].E sp|Q86U44|MTA70_HUMAN 1 955.4868 0.02 138425 4808 2 955.486626 478.7507 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 8.76 1458.5 - 4.03E+06 - - - -0.1643 - 1.903 0.488 - 412.3 1 1 0 -0.0002 8 0 0 0 8.95E+05 4.06E+07 - - - 4.5859 0.9999 221125_WJC_METTL3_EV_vs_WT_F10.04810.04810.3 0.000194 Sep-36 R.K[136.11]QDSGHLDLR[166.11].N "sp|Q86U44|MTA70_HUMAN,tr|B4E349|B4E349_HUMAN,tr|F5H6D8|F5H6D8_HUMAN,tr|B4DTN4|B4DTN4_HUMAN" 4 1185.6221 0.7 138427 4810 3 1185.620172 396.2146 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 6.75 1458.7 - 875886 - - - -1.6304 - 2.023 0.426 - 101.1 1 2 0 -0.0019 10 0 0 0 3.45E+06 4.95E+06 - - - 5.3466 0.9998 221125_WJC_METTL3_EV_vs_WT_F10.04811.04811.3 0.0247 Nov-40 K.HLNNEHALDDR[166.11].S "sp|O15409|FOXP2_HUMAN,tr|Q0PRL4|Q0PRL4_HUMAN,tr|Q8N6B5|Q8N6B5_HUMAN,tr|A0A0U1RQE0|A0A0U1RQE0_HUMAN,tr|A0A0U1RQR8|A0A0U1RQR8_HUMAN,tr|A8MUV4|A8MUV4_HUMAN,tr|A0A0U1RQM2|A0A0U1RQM2_HUMAN,tr|A0A0U1RQY3|A0A0U1RQY3_HUMAN,tr|A0A0U1RQE6|A0A0U1RQE6_HUMAN" 9 1342.6253 7.3 138428 4811 3 1342.624545 448.5491 Forkhead box protein P2 OS=Homo sapiens OX=9606 GN=FOXP2 PE=1 SV=2 5.21 1458.7 - 753288 - - - -0.5966 - 2.147 0.338 - 124.5 1 2 0 -0.0008 11 0 0 0 2.80E+07 3.83E+06 - - - 4.4787 0.9982 221125_WJC_METTL3_EV_vs_WT_F10.04817.04817.3 0.00969 Aug-64 R.ASGAGGQHVNTTDSAVR[166.11].L "sp|Q9UGC7|RF1ML_HUMAN,tr|X6RKB4|X6RKB4_HUMAN,tr|Q5TF45|Q5TF45_HUMAN" 3 1636.7793 2.36 138434 4817 3 1636.779016 546.6004 "Peptide chain release factor 1-like, mitochondrial OS=Homo sapiens OX=9606 GN=MTRF1L PE=1 SV=1" 6.79 1459.5 - 109119 - - - -0.1613 - 1.536 0.293 - 47.7 1 2 0 -0.0003 17 0 0 0 1.27E+06 5.39E+05 - - - 2.8908 1 221125_WJC_METTL3_EV_vs_WT_F10.04820.04820.2 1.50E-06 15/18 K.KDDAITAYKK.Y "sp|Q9BY77|PDIP3_HUMAN,tr|F6VRR5|F6VRR5_HUMAN" 2 1151.6186 1.47 138435 4820 2 1151.618528 576.8166 Polymerase delta-interacting protein 3 OS=Homo sapiens OX=9606 GN=POLDIP3 PE=1 SV=2 8.43 1459.9 - 1.87E+06 - - - -0.0964 - 2.753 0.583 - 731.3 1 2 0 -0.0001 10 0 0 0 2.35E+07 1.60E+07 - - - 6.1737 0.9987 221125_WJC_METTL3_EV_vs_WT_F10.04821.04821.2 0.000655 14-Nov K.ADK[136.11]DYHFK[136.11].V "sp|P06748|NPM_HUMAN,tr|A0A7I2V4G8|A0A7I2V4G8_HUMAN,tr|A0A7I2YQC0|A0A7I2YQC0_HUMAN,tr|A0A7I2V433|A0A7I2V433_HUMAN,tr|A0A7I2V579|A0A7I2V579_HUMAN,tr|A0A7I2V2X9|A0A7I2V2X9_HUMAN,tr|A0A7I2V3G5|A0A7I2V3G5_HUMAN,tr|A0A7I2V5S2|A0A7I2V5S2_HUMAN,tr|A0A7I2V3U2|A0A7I2V3U2_HUMAN" 9 1038.5105 0.85 138436 4821 2 1038.510862 520.2625 Nucleophosmin OS=Homo sapiens OX=9606 GN=NPM1 PE=1 SV=2 6.79 1460 - 1.53E+06 - - - 0.3052 - 2.156 0.496 - 452.2 1 2 1 0.0003 8 0 0 0 3.33E+07 3.92E+07 - - - 5.0214 0.9999 221125_WJC_METTL3_EV_vs_WT_F10.04824.04824.3 8.48E-05 Dec-44 R.VVEC[160.03]QLETHNRK.M "sp|Q9H4A3|WNK1_HUMAN,tr|F5GWT4|F5GWT4_HUMAN,tr|A0A6Q8PFM0|A0A6Q8PFM0_HUMAN" 3 1511.7515 1.23 138439 4824 3 1511.753959 504.9244 Serine\threonine-protein kinase WNK1 OS=Homo sapiens OX=9606 GN=WNK1 PE=1 SV=2 6.72 1460.2 - 563677 - - - 1.6524 - 2.438 0.474 - 219 1 2 0 0.0025 12 0 0 0 4.99E+06 4.06E+06 - - - 6.2942 1 221125_WJC_METTL3_EV_vs_WT_F10.04825.04825.2 2.87E-07 15/26 R.DSDAGSSTPTTSTR[166.11].S "sp|P51532|SMCA4_HUMAN,tr|A0A2R8Y5K3|A0A2R8Y5K3_HUMAN,tr|A0A2R8Y7S2|A0A2R8Y7S2_HUMAN,tr|A0A2R8Y7F3|A0A2R8Y7F3_HUMAN,tr|A0A2R8YGG3|A0A2R8YGG3_HUMAN,tr|A0A2R8Y523|A0A2R8Y523_HUMAN,tr|A0A2R8Y6V2|A0A2R8Y6V2_HUMAN,tr|Q9HBD4|Q9HBD4_HUMAN,tr|K7EQF0|K7EQF0_HUMAN,tr|A0A2R8Y440|A0A2R8Y440_HUMAN,tr|A0A2R8YFK5|A0A2R8YFK5_HUMAN,tr|A0A2R8YDA1|A0A2R8YDA1_HUMAN,tr|A0A2R8Y7Y7|A0A2R8Y7Y7_HUMAN,tr|A0A2R8YF58|A0A2R8YF58_HUMAN,tr|A0A2R8Y526|A0A2R8Y526_HUMAN,tr|K7EP28|K7EP28_HUMAN,tr|A0A2R8YG32|A0A2R8YG32_HUMAN,tr|A0A2R8Y6N0|A0A2R8Y6N0_HUMAN,tr|A0A2R8YF80|A0A2R8YF80_HUMAN,tr|A0A2R8Y4P4|A0A2R8Y4P4_HUMAN,tr|A0A2R8Y4C5|A0A2R8Y4C5_HUMAN" 21 1391.604 0.75 138440 4825 2 1391.604423 696.8093 Transcription activator BRG1 OS=Homo sapiens OX=9606 GN=SMARCA4 PE=1 SV=2 4.21 1460.3 - 244055 - - - 0.3032 - 3.107 0.603 - 801.9 1 2 0 0.0004 14 0 0 0 8.86E+06 1.18E+07 - - - 6.3395 0.9995 221125_WJC_METTL3_EV_vs_WT_F10.04827.04827.2 0.000901 30-Sep R.LTDSSPSSTSTSNSQR[166.11].L sp|Q5VT06|CE350_HUMAN 1 1663.7525 1.8 138442 4827 2 1663.750082 832.8835 Centrosome-associated protein 350 OS=Homo sapiens OX=9606 GN=CEP350 PE=1 SV=1 5.84 1460.6 - 177827 - - - -1.4269 - 2.112 0.334 - 136.1 1 2 0 -0.0024 16 0 0 0 4.50E+06 2.50E+06 - - - 3.3453 0.9986 221125_WJC_METTL3_EV_vs_WT_F10.04834.04834.2 0.0575 14/20 R.EK[136.11]LHGTVVEGR[166.11].K "sp|O43251|RFOX2_HUMAN,sp|Q9NWB1|RFOX1_HUMAN,tr|A0A6Q8PGE0|A0A6Q8PGE0_HUMAN,tr|A0A6Q8PH77|A0A6Q8PH77_HUMAN,tr|A0A286YEU2|A0A286YEU2_HUMAN,tr|A0A087X2B1|A0A087X2B1_HUMAN,tr|F8VR27|F8VR27_HUMAN,tr|B7Z1U7|B7Z1U7_HUMAN,tr|B0QYV1|B0QYV1_HUMAN,tr|A0A6Q8PHA3|A0A6Q8PHA3_HUMAN,tr|F8VZY7|F8VZY7_HUMAN,tr|B0QYY4|B0QYY4_HUMAN,tr|J3KNW3|J3KNW3_HUMAN,tr|F8VZG9|F8VZG9_HUMAN,tr|F8VRS4|F8VRS4_HUMAN,tr|A0A6Q8PFM4|A0A6Q8PFM4_HUMAN,tr|S4R469|S4R469_HUMAN,tr|A0A804HKG7|A0A804HKG7_HUMAN,tr|A0A0G2JRD1|A0A0G2JRD1_HUMAN,tr|A0A0G2JRA5|A0A0G2JRA5_HUMAN,tr|A0A804HJM2|A0A804HJM2_HUMAN,tr|I3L1D4|I3L1D4_HUMAN,tr|S4R3K7|S4R3K7_HUMAN" 23 1241.6847 1.1 138447 4834 2 1241.684505 621.8496 RNA binding protein fox-1 homolog 2 OS=Homo sapiens OX=9606 GN=RBFOX2 PE=1 SV=3 6.86 1461.4 - 1.15E+06 - - - -0.1611 - 2.423 0.462 - 680 1 2 1 -0.0002 11 0 0 0 2.77E+07 2.51E+07 - - - 4.8474 1 221125_WJC_METTL3_EV_vs_WT_F10.04838.04838.2 1.10E-08 13/26 R.DSDAGSSTPTTSTR.S "sp|P51532|SMCA4_HUMAN,tr|A0A2R8Y5K3|A0A2R8Y5K3_HUMAN,tr|A0A2R8Y7S2|A0A2R8Y7S2_HUMAN,tr|A0A2R8Y7F3|A0A2R8Y7F3_HUMAN,tr|A0A2R8YGG3|A0A2R8YGG3_HUMAN,tr|A0A2R8Y523|A0A2R8Y523_HUMAN,tr|A0A2R8Y6V2|A0A2R8Y6V2_HUMAN,tr|Q9HBD4|Q9HBD4_HUMAN,tr|K7EQF0|K7EQF0_HUMAN,tr|A0A2R8Y440|A0A2R8Y440_HUMAN,tr|A0A2R8YFK5|A0A2R8YFK5_HUMAN,tr|A0A2R8YDA1|A0A2R8YDA1_HUMAN,tr|A0A2R8Y7Y7|A0A2R8Y7Y7_HUMAN,tr|A0A2R8YF58|A0A2R8YF58_HUMAN,tr|A0A2R8Y526|A0A2R8Y526_HUMAN,tr|K7EP28|K7EP28_HUMAN,tr|A0A2R8YG32|A0A2R8YG32_HUMAN,tr|A0A2R8Y6N0|A0A2R8Y6N0_HUMAN,tr|A0A2R8YF80|A0A2R8YF80_HUMAN,tr|A0A2R8Y4P4|A0A2R8Y4P4_HUMAN,tr|A0A2R8Y4C5|A0A2R8Y4C5_HUMAN" 21 1381.5957 0.75 138451 4838 2 1381.592541 691.8051 Transcription activator BRG1 OS=Homo sapiens OX=9606 GN=SMARCA4 PE=1 SV=2 4.21 1461.9 - 314752 - - - -2.3089 - 2.554 0.651 - 607.5 1 2 0 -0.0032 14 0 0 0 8.86E+06 1.18E+07 - - - 6.2013 1 221125_WJC_METTL3_EV_vs_WT_F10.04843.04843.3 0.0779 13/40 R.HAQTISGHALR[166.11].L "sp|Q9UBN7|HDAC6_HUMAN,tr|A0A2R8Y4G2|A0A2R8Y4G2_HUMAN,tr|A0A2R8YDE6|A0A2R8YDE6_HUMAN" 3 1199.6399 1.38 138454 4843 3 1199.638882 400.8872 Histone deacetylase 6 OS=Homo sapiens OX=9606 GN=HDAC6 PE=1 SV=2 9.76 1462.6 - 2.28E+06 - - - -0.8261 - 2.715 0.481 - 234.5 1 2 0 -0.001 11 0 0 0 2.24E+07 1.62E+07 - - - 6.7398 0.9999 221125_WJC_METTL3_EV_vs_WT_F10.04844.04844.3 1.21E-05 14/52 K.GRDVIAQSQSGTGK.T "sp|P38919|IF4A3_HUMAN,tr|I3L3H2|I3L3H2_HUMAN" 2 1402.7165 1.46 138455 4844 3 1402.717286 468.5794 Eukaryotic initiation factor 4A-III OS=Homo sapiens OX=9606 GN=EIF4A3 PE=1 SV=4 8.75 1462.6 - 2.39E+06 - - - 0.5924 - 3.128 0.515 - 393.3 1 2 1 0.0008 14 0 0 0 1.39E+08 9.52E+07 - - - 7.3121 0.9982 221125_WJC_METTL3_EV_vs_WT_F10.04845.04845.2 0.00366 13/20 R.EKLHGTVVEGR.K "sp|O43251|RFOX2_HUMAN,sp|Q9NWB1|RFOX1_HUMAN,tr|A0A6Q8PGE0|A0A6Q8PGE0_HUMAN,tr|A0A6Q8PH77|A0A6Q8PH77_HUMAN,tr|A0A286YEU2|A0A286YEU2_HUMAN,tr|A0A087X2B1|A0A087X2B1_HUMAN,tr|F8VR27|F8VR27_HUMAN,tr|B7Z1U7|B7Z1U7_HUMAN,tr|B0QYV1|B0QYV1_HUMAN,tr|A0A6Q8PHA3|A0A6Q8PHA3_HUMAN,tr|F8VZY7|F8VZY7_HUMAN,tr|B0QYY4|B0QYY4_HUMAN,tr|J3KNW3|J3KNW3_HUMAN,tr|F8VZG9|F8VZG9_HUMAN,tr|F8VRS4|F8VRS4_HUMAN,tr|A0A6Q8PFM4|A0A6Q8PFM4_HUMAN,tr|S4R469|S4R469_HUMAN,tr|A0A804HKG7|A0A804HKG7_HUMAN,tr|A0A0G2JRD1|A0A0G2JRD1_HUMAN,tr|A0A0G2JRA5|A0A0G2JRA5_HUMAN,tr|A0A804HJM2|A0A804HJM2_HUMAN,tr|I3L1D4|I3L1D4_HUMAN,tr|S4R3K7|S4R3K7_HUMAN" 23 1223.6622 1.1 138456 4845 2 1223.661674 612.8384 RNA binding protein fox-1 homolog 2 OS=Homo sapiens OX=9606 GN=RBFOX2 PE=1 SV=3 6.86 1462.7 - 2.21E+06 - - - -0.4585 - 2.317 0.416 - 565.4 1 2 1 -0.0006 11 0 0 0 2.77E+07 2.51E+07 - - - 4.3865 0.9998 221125_WJC_METTL3_EV_vs_WT_F10.04846.04846.3 0.000475 13/52 K.GR[166.11]DVIAQSQSGTGK[136.11].T "sp|P38919|IF4A3_HUMAN,tr|I3L3H2|I3L3H2_HUMAN" 2 1420.7389 1.46 138457 4846 3 1420.740185 474.5869 Eukaryotic initiation factor 4A-III OS=Homo sapiens OX=9606 GN=EIF4A3 PE=1 SV=4 8.75 1462.8 - 2.13E+06 - - - 0.8869 - 2.755 0.466 - 335.4 1 2 1 0.0013 14 0 0 0 1.39E+08 9.52E+07 - - - 6.4283 1 221125_WJC_METTL3_EV_vs_WT_F10.04852.04852.3 3.03E-06 15/48 R.SSVGPSKPVSQPR.R sp|Q9Y657|SPIN1_HUMAN 1 1324.7099 1.99 138461 4852 3 1324.70804 442.5772 Spindlin-1 OS=Homo sapiens OX=9606 GN=SPIN1 PE=1 SV=3 11 1463.4 - 1.40E+06 - - - -1.4139 - 3.016 0.535 - 275.8 1 2 0 -0.0019 13 0 0 0 4.70E+07 2.36E+07 - - - 7.4973 1 221125_WJC_METTL3_EV_vs_WT_F10.04856.04856.2 1.91E-08 22/26 K.GRDVIAQSQSGTGK.T "sp|P38919|IF4A3_HUMAN,tr|I3L3H2|I3L3H2_HUMAN" 2 1402.7165 1.43 138465 4856 2 1402.717001 702.3655 Eukaryotic initiation factor 4A-III OS=Homo sapiens OX=9606 GN=EIF4A3 PE=1 SV=4 8.75 1463.9 - 542603 - - - 0.3892 - 4.105 0.58 - 1217.2 1 2 1 0.0005 14 0 0 0 1.66E+07 1.16E+07 - - - 6.8686 1 221125_WJC_METTL3_EV_vs_WT_F10.04857.04857.2 8.85E-05 19/26 K.GR[166.11]DVIAQSQSGTGK[136.11].T "sp|P38919|IF4A3_HUMAN,tr|I3L3H2|I3L3H2_HUMAN" 2 1420.7389 1.43 138466 4857 2 1420.736063 711.3767 Eukaryotic initiation factor 4A-III OS=Homo sapiens OX=9606 GN=EIF4A3 PE=1 SV=4 8.75 1464 - 409164 - - - -2.0144 - 3.923 0.581 - 774.1 1 2 1 -0.0029 14 0 0 0 1.66E+07 1.16E+07 - - - 6.7614 0.9999 221125_WJC_METTL3_EV_vs_WT_F10.04865.04865.3 0.00251 Dec-48 R.SSVGPSK[136.11]PVSQPR[166.11].R sp|Q9Y657|SPIN1_HUMAN 1 1342.7324 2.05 138472 4865 3 1342.732228 448.5847 Spindlin-1 OS=Homo sapiens OX=9606 GN=SPIN1 PE=1 SV=3 11 1464.9 - 1.55E+06 - - - -0.1154 - 2.301 0.386 - 160.2 1 2 0 -0.0002 13 0 0 0 5.76E+07 2.82E+07 - - - 5.1029 0.9996 221125_WJC_METTL3_EV_vs_WT_F10.04871.04871.2 0.00232 26-Jul R.TDPPDGQQDSEC[160.03]NR.N sp|Q9NUQ3|TXLNG_HUMAN 1 1617.6325 1.23 138478 4871 2 1617.630128 809.8235 Gamma-taxilin OS=Homo sapiens OX=9606 GN=TXLNG PE=1 SV=2 3.84 1465.6 - 144640 - - - -1.4836 - 1.212 0.572 - 54.2 1 2 0 -0.0024 14 0 0 0 1.33E+06 1.08E+06 - - - 3.7475 0.9999 221125_WJC_METTL3_EV_vs_WT_F10.04876.04876.3 0.00034 13/48 K.NGGGVGGGELDKK.D sp|Q9H7S9|ZN703_HUMAN 1 1186.5942 0.56 138481 4876 3 1186.594329 396.5387 Zinc finger protein 703 OS=Homo sapiens OX=9606 GN=ZNF703 PE=1 SV=1 6.07 1466.3 - 787053 - - - 0.0961 - 2.245 0.404 - 202.5 1 2 0 0.0001 13 0 0 0 6.15E+06 1.09E+07 - - - 5.2368 1 221125_WJC_METTL3_EV_vs_WT_F10.04878.04878.3 4.43E-07 16/52 R.TAEHEAAQQDLQSK[136.11].F sp|Q86UP2|KTN1_HUMAN 1 1562.7416 2.27 138483 4878 3 1562.740905 521.9211 Kinectin OS=Homo sapiens OX=9606 GN=KTN1 PE=1 SV=1 4.65 1466.5 - 596178 - - - -0.4537 - 2.901 0.54 - 581.2 1 2 0 -0.0007 14 0 0 0 2.39E+07 1.06E+07 - - - 7.3907 0.9998 221125_WJC_METTL3_EV_vs_WT_F10.04883.04883.2 4.29E-11 13/26 K.VAHEINHGIGQAGK.E "sp|Q6UWP8|SBSN_HUMAN,tr|K7ESC4|K7ESC4_HUMAN" 2 1429.7426 999 138488 4883 2 1429.739733 715.8786 Suprabasin OS=Homo sapiens OX=9606 GN=SBSN PE=1 SV=2 6.89 1467.1 - 219961 - - - -2.0123 - 2.651 0.561 - 612.6 1 2 0 -0.0029 14 0 0 0 2.02E+06 0.00E+00 - - - 5.6302 0.9998 221125_WJC_METTL3_EV_vs_WT_F10.04886.04886.2 0.0678 22-Sep K.RDDGYEAAASSK.T "sp|O43290|SNUT1_HUMAN,tr|E9PQI8|E9PQI8_HUMAN" 2 1268.5633 2.59 138491 4886 2 1268.562515 635.2889 U4\U6.U5 tri-snRNP-associated protein 1 OS=Homo sapiens OX=9606 GN=SART1 PE=1 SV=1 4.56 1467.4 - 124986 - - - -0.6259 - 2.175 0.423 - 231 1 2 0 -0.0008 12 0 0 0 1.44E+06 5.56E+05 - - - 4.2095 1 221125_WJC_METTL3_EV_vs_WT_F10.04891.04891.3 6.57E-07 15/52 R.TAEHEAAQQDLQSK.F sp|Q86UP2|KTN1_HUMAN 1 1554.7274 2.27 138494 4891 3 1554.728402 519.2497 Kinectin OS=Homo sapiens OX=9606 GN=KTN1 PE=1 SV=1 4.65 1468 - 5.00E+06 - - - 0.6355 - 2.95 0.575 - 466.3 1 2 0 0.001 14 0 0 0 2.39E+07 1.06E+07 - - - 7.8253 0.9999 221125_WJC_METTL3_EV_vs_WT_F10.04893.04893.3 3.62E-06 Nov-48 K.YTKQDGEC[160.03]GTLSK.G sp|Q5D862|FILA2_HUMAN 1 1485.677 3.13 138496 4893 3 1485.678268 496.2329 Filaggrin-2 OS=Homo sapiens OX=9606 GN=FLG2 PE=1 SV=1 6.06 1468.1 - 2.84E+06 - - - 0.8811 - 2.34 0.546 - 98.5 1 2 1 0.0013 13 0 0 0 1.28E+07 4.11E+06 - - - 6.932 0.9996 221125_WJC_METTL3_EV_vs_WT_F10.04894.04894.3 0.000712 13/36 K.YTPPPHHIGK.G sp|O43920|NDUS5_HUMAN 1 1145.5982 0.08 138497 4894 3 1145.598712 382.8733 NADH dehydrogenase [ubiquinone] iron-sulfur protein 5 OS=Homo sapiens OX=9606 GN=NDUFS5 PE=1 SV=3 8.61 1468.2 - 1.34E+06 - - - 0.4661 - 2.157 0.296 - 252.8 1 2 0 0.0005 10 0 0 0 1.03E+07 1.22E+08 - - - 4.085 1 221125_WJC_METTL3_EV_vs_WT_F10.04895.04895.3 6.35E-05 13/44 K.RDDGYEAAASSK.T "sp|O43290|SNUT1_HUMAN,tr|E9PQI8|E9PQI8_HUMAN" 2 1268.5633 2.08 138498 4895 3 1268.563787 423.8617 U4\U6.U5 tri-snRNP-associated protein 1 OS=Homo sapiens OX=9606 GN=SART1 PE=1 SV=1 4.56 1468.3 - 1.32E+06 - - - 0.3768 - 2.338 0.587 - 308.9 1 2 0 0.0005 12 0 0 0 5.93E+06 2.85E+06 - - - 7.4385 0.9997 221125_WJC_METTL3_EV_vs_WT_F10.04901.04901.2 0.00167 24-Oct R.SSVGPSKPVSQPR.R sp|Q9Y657|SPIN1_HUMAN 1 1324.7099 2.32 138504 4901 2 1324.710311 663.3622 Spindlin-1 OS=Homo sapiens OX=9606 GN=SPIN1 PE=1 SV=3 11 1469 - 385981 - - - 0.3004 - 1.98 0.381 - 218.7 1 2 0 0.0004 13 0 0 0 2.63E+06 1.13E+06 - - - 3.6081 1 221125_WJC_METTL3_EV_vs_WT_F10.04902.04902.2 2.61E-09 17/26 R.TAEHEAAQQDLQSK.F sp|Q86UP2|KTN1_HUMAN 1 1554.7274 2.4 138505 4902 2 1554.728576 778.371 Kinectin OS=Homo sapiens OX=9606 GN=KTN1 PE=1 SV=1 4.65 1469.2 - 357908 - - - 0.7474 - 3.454 0.669 - 1116.7 1 2 0 0.0012 14 0 0 0 2.06E+06 8.59E+05 - - - 7.0924 1 221125_WJC_METTL3_EV_vs_WT_F10.04906.04906.2 2.25E-12 14/26 R.TAEHEAAQQDLQSK[136.11].F sp|Q86UP2|KTN1_HUMAN 1 1562.7416 -1 138509 4906 2 1562.739891 782.3781 Kinectin OS=Homo sapiens OX=9606 GN=KTN1 PE=1 SV=1 4.65 1469.7 - 138171 - - - -1.1025 - 3.073 0.691 - 689 1 2 0 -0.0017 14 0 0 0 0.00E+00 0.00E+00 - - - 6.9614 1 221125_WJC_METTL3_EV_vs_WT_F10.04909.04909.2 1.93E-08 14/26 K.EESAASGGAAYTKR.Y "sp|Q9Y2W1|TR150_HUMAN,tr|A0A3B3ITZ9|A0A3B3ITZ9_HUMAN" 2 1396.6583 2.62 138512 4909 2 1396.66189 699.3364 Thyroid hormone receptor-associated protein 3 OS=Homo sapiens OX=9606 GN=THRAP3 PE=1 SV=2 6.24 1470.1 - 114650 - - - 2.5905 - 2.83 0.62 - 628.4 1 2 0 0.0036 14 0 0 0 2.69E+06 1.03E+06 - - - 6.2297 0.9997 221125_WJC_METTL3_EV_vs_WT_F10.04912.04912.2 0.00156 22-Jul K.R[166.11]DDGYEAAASSK[136.11].T "sp|O43290|SNUT1_HUMAN,tr|E9PQI8|E9PQI8_HUMAN" 2 1286.5858 -1 138514 4912 2 1286.585713 644.3002 U4\U6.U5 tri-snRNP-associated protein 1 OS=Homo sapiens OX=9606 GN=SART1 PE=1 SV=1 4.56 1470.5 - 105731 - - - -0.0513 - 1.725 0.423 - 112.3 1 2 0 -0.0001 12 0 0 0 0.00E+00 0.00E+00 - - - 3.5998 1 221125_WJC_METTL3_EV_vs_WT_F10.04913.04913.3 1.81E-11 22/52 K.EESAASGGAAYTKR.Y "sp|Q9Y2W1|TR150_HUMAN,tr|A0A3B3ITZ9|A0A3B3ITZ9_HUMAN" 2 1396.6583 2.15 138515 4913 3 1396.660416 466.56 Thyroid hormone receptor-associated protein 3 OS=Homo sapiens OX=9606 GN=THRAP3 PE=1 SV=2 6.24 1470.5 - 1.49E+07 - - - 1.5351 - 3.612 0.639 - 1100 1 2 0 0.0021 14 0 0 0 5.84E+07 2.72E+07 - - - 9.0766 1 221125_WJC_METTL3_EV_vs_WT_F10.04914.04914.3 6.32E-05 21/52 K.EESAASGGAAYTK[136.11]R[166.11].Y "sp|Q9Y2W1|TR150_HUMAN,tr|A0A3B3ITZ9|A0A3B3ITZ9_HUMAN" 2 1414.6807 2.1 138516 4914 3 1414.682045 472.5675 Thyroid hormone receptor-associated protein 3 OS=Homo sapiens OX=9606 GN=THRAP3 PE=1 SV=2 6.24 1470.6 - 6.53E+06 - - - 0.9211 - 3.483 0.558 - 1080 1 2 0 0.0013 14 0 0 0 5.84E+07 2.79E+07 - - - 8.0771 0.9905 221125_WJC_METTL3_EV_vs_WT_F10.04915.04915.2 0.0799 14-Oct K.LRDDFEKK.M "sp|Q9Y2W1|TR150_HUMAN,tr|A0A3B3ITZ9|A0A3B3ITZ9_HUMAN" 2 1049.5506 2.7 138517 4915 2 1049.551623 525.7826 Thyroid hormone receptor-associated protein 3 OS=Homo sapiens OX=9606 GN=THRAP3 PE=1 SV=2 6.12 1470.7 - 1.91E+06 - - - 1.0138 - 1.778 0.271 - 339.9 1 2 1 0.0011 8 0 0 0 5.92E+06 2.20E+06 - - - 2.7779 0.9978 221125_WJC_METTL3_EV_vs_WT_F10.04917.04917.3 0.123 13/36 R.HRAEAPPLER.E "sp|O75569|PRKRA_HUMAN,tr|A0A7I2V332|A0A7I2V332_HUMAN,tr|A0A7I2V3J2|A0A7I2V3J2_HUMAN,tr|A0A7I2V5C2|A0A7I2V5C2_HUMAN,tr|A0A7I2V5H3|A0A7I2V5H3_HUMAN,tr|G5E9Q4|G5E9Q4_HUMAN,tr|A0A7I2YQ87|A0A7I2YQ87_HUMAN,tr|A0A7I2V3L6|A0A7I2V3L6_HUMAN" 8 1174.6207 1.82 138519 4917 3 1174.62193 392.5475 Interferon-inducible double-stranded RNA-dependent protein kinase activator A OS=Homo sapiens OX=9606 GN=PRKRA PE=1 SV=1 6.76 1470.8 - 1.15E+06 - - - 1.0437 - 2.503 0.246 - 367.3 1 2 1 0.0012 10 0 0 0 5.04E+06 2.77E+06 - - - 3.9618 1 221125_WJC_METTL3_EV_vs_WT_F10.04920.04920.3 8.18E-08 15/52 R.DAAAPAEPQAQHTR.S "sp|O76024|WFS1_HUMAN,tr|A0A804HIL0|A0A804HIL0_HUMAN,tr|A0A669KAX3|A0A669KAX3_HUMAN,tr|A0A804HK77|A0A804HK77_HUMAN,tr|A0A804HKM5|A0A804HKM5_HUMAN,tr|A0A804HIL2|A0A804HIL2_HUMAN" 6 1461.6961 0.91 138522 4920 3 1461.696992 488.2393 Wolframin OS=Homo sapiens OX=9606 GN=WFS1 PE=1 SV=2 5.32 1471.1 - 928990 - - - 0.6417 - 3.007 0.44 - 351.2 1 2 0 0.0009 14 0 0 0 3.29E+06 3.62E+06 - - - 6.3711 0.9998 221125_WJC_METTL3_EV_vs_WT_F10.04922.04922.3 1.63E-05 15/48 R.SSNLRGEC[160.03]TPTQR.E sp|Q8TEM1|PO210_HUMAN 1 1504.7052 1.06 138524 4922 3 1504.707802 502.5757 Nuclear pore membrane glycoprotein 210 OS=Homo sapiens OX=9606 GN=NUP210 PE=1 SV=3 7.97 1471.3 - 623401 - - - 1.7033 - 3.131 0.473 - 325.7 1 2 1 0.0026 13 0 0 0 3.98E+06 3.74E+06 - - - 6.9073 1 221125_WJC_METTL3_EV_vs_WT_F10.04923.04923.3 3.43E-08 17/44 R.TSNEVTVETDK[136.11]K[136.11].T "sp|Q9NRY5|F1142_HUMAN,tr|E7ESJ7|E7ESJ7_HUMAN" 2 1365.6958 1.27 138525 4923 3 1365.698825 456.2392 Protein FAM114A2 OS=Homo sapiens OX=9606 GN=FAM114A2 PE=1 SV=4 4.68 1471.4 - 547959 - - - 2.1864 - 2.945 0.526 - 587 1 2 0 0.003 12 0 0 0 1.55E+08 1.21E+08 - - - 7.3975 0.9905 221125_WJC_METTL3_EV_vs_WT_F10.04926.04926.3 0.015 13/44 R.YRTEAHQDVVGR.F "sp|Q9H0A0|NAT10_HUMAN,tr|E9PMU0|E9PMU0_HUMAN,tr|A0A087WV29|A0A087WV29_HUMAN" 3 1429.7062 -1 138528 4926 3 1429.699972 477.576 RNA cytidine acetyltransferase OS=Homo sapiens OX=9606 GN=NAT10 PE=1 SV=2 6.75 1471.8 - 411646 - - - -4.3736 - 2.341 0.328 - 202.2 1 2 1 -0.0063 12 0 0 0 0.00E+00 0.00E+00 - - - 4.5528 0.987 221125_WJC_METTL3_EV_vs_WT_F10.04928.04928.2 0.0741 22-Nov E.SAASGGAAYTKR.Y "sp|Q9Y2W1|TR150_HUMAN,tr|A0A3B3ITZ9|A0A3B3ITZ9_HUMAN" 2 1138.5731 0.56 138530 4928 2 1138.573861 570.2938 Thyroid hormone receptor-associated protein 3 OS=Homo sapiens OX=9606 GN=THRAP3 PE=1 SV=2 9.99 1472 - 224734 - - - 0.6816 - 2.414 0.379 - 381.4 1 1 0 0.0008 12 0 0 0 3.22E+07 5.76E+07 - - - 4.1589 0.999 221125_WJC_METTL3_EV_vs_WT_F10.04929.04929.2 2.24E-08 26-Dec K.EESAASGGAAYTK[136.11]R[166.11].Y "sp|Q9Y2W1|TR150_HUMAN,tr|A0A3B3ITZ9|A0A3B3ITZ9_HUMAN" 2 1414.6807 2.62 138531 4929 2 1414.685497 708.3476 Thyroid hormone receptor-associated protein 3 OS=Homo sapiens OX=9606 GN=THRAP3 PE=1 SV=2 6.24 1472.2 - 212649 - - - 3.3612 - 2.578 0.397 - 452.2 1 2 0 0.0048 14 0 0 0 2.69E+06 1.03E+06 - - - 4.3482 0.9999 221125_WJC_METTL3_EV_vs_WT_F10.04935.04935.3 0.00187 14/44 R.TSNEVTVETDKK.T "sp|Q9NRY5|F1142_HUMAN,tr|E7ESJ7|E7ESJ7_HUMAN" 2 1349.6674 1.27 138536 4935 3 1349.668647 450.8964 Protein FAM114A2 OS=Homo sapiens OX=9606 GN=FAM114A2 PE=1 SV=4 4.68 1472.7 - 4.39E+06 - - - 0.895 - 2.527 0.393 - 301.1 1 2 0 0.0012 12 0 0 0 1.55E+08 1.21E+08 - - - 5.4908 0.9965 221125_WJC_METTL3_EV_vs_WT_F10.04937.04937.3 4.07E-06 13/32 N.KYEDEINKR.T "sp|P48668|K2C6C_HUMAN,sp|P05787|K2C8_HUMAN,sp|Q01546|K22O_HUMAN,sp|Q7Z794|K2C1B_HUMAN,sp|P12035|K2C3_HUMAN,sp|P04264|K2C1_HUMAN,sp|P04259|K2C6B_HUMAN,sp|P13647|K2C5_HUMAN,sp|P35908|K22E_HUMAN,sp|P02538|K2C6A_HUMAN,tr|F8VUG2|F8VUG2_HUMAN,tr|F8W0C6|F8W0C6_HUMAN,tr|F8VP67|F8VP67_HUMAN,tr|F8W1U3|F8W1U3_HUMAN" 14 1193.6041 10.53 138538 4937 3 1193.605255 398.8753 "Keratin, type II cytoskeletal 6C OS=Homo sapiens OX=9606 GN=KRT6C PE=1 SV=3" 6.18 1472.9 - 1.21E+06 - - - 1.0087 - 2.354 0.482 - 258.6 1 1 0 0.0012 9 0 0 0 6.19E+06 5.88E+05 - - - 6.4936 0.9999 221125_WJC_METTL3_EV_vs_WT_F10.04938.04938.3 0.00272 Oct-32 R.IQNWHEEHR[166.11].G "sp|P35241|RADI_HUMAN,tr|A0A2R8Y5S7|A0A2R8Y5S7_HUMAN,tr|A0A2R8Y7M3|A0A2R8Y7M3_HUMAN" 3 1257.5878 0.14 138539 4938 3 1257.587264 420.2032 Radixin OS=Homo sapiens OX=9606 GN=RDX PE=1 SV=1 6 1472.9 - 1.21E+06 - - - -0.4564 - 2.152 0.365 - 273.6 1 2 0 -0.0006 9 0 0 0 4.26E+05 3.13E+06 - - - 4.919 1 221125_WJC_METTL3_EV_vs_WT_F10.04943.04943.3 7.63E-09 17/56 K.LSDSGDPDKESPGC[160.03]K.R sp|A6NJT0|UNC4_HUMAN 1 1590.6832 2.69 138544 4943 3 1590.684065 531.235 Homeobox protein unc-4 homolog OS=Homo sapiens OX=9606 GN=UNCX PE=3 SV=1 4.23 1473.5 - 531028 - - - 0.5652 - 3.121 0.626 - 497.9 1 2 1 0.0009 15 0 0 0 2.26E+06 8.42E+05 - - - 8.4889 1 221125_WJC_METTL3_EV_vs_WT_F10.04948.04948.2 9.45E-08 13/22 R.TSNEVTVETDKK.T "sp|Q9NRY5|F1142_HUMAN,tr|E7ESJ7|E7ESJ7_HUMAN" 2 1349.6674 1.33 138549 4948 2 1349.667903 675.841 Protein FAM114A2 OS=Homo sapiens OX=9606 GN=FAM114A2 PE=1 SV=4 4.68 1474.1 - 276939 - - - 0.3438 - 2.832 0.601 - 757.3 1 2 0 0.0005 12 0 0 0 1.32E+07 9.96E+06 - - - 6.2188 0.9992 221125_WJC_METTL3_EV_vs_WT_F10.04949.04949.2 0.00231 24-Jul R.SSVGPSK[136.11]PVSQPR[166.11].R sp|Q9Y657|SPIN1_HUMAN 1 1342.7324 2.76 138550 4949 2 1342.732847 672.3735 Spindlin-1 OS=Homo sapiens OX=9606 GN=SPIN1 PE=1 SV=3 11 1474.2 - 272522 - - - 0.3456 - 1.468 0.344 - 83.5 1 2 0 0.0005 13 0 0 0 5.44E+06 1.97E+06 - - - 2.5669 1 221125_WJC_METTL3_EV_vs_WT_F10.04951.04951.2 2.85E-08 15/22 R.TSNEVTVETDK[136.11]K[136.11].T "sp|Q9NRY5|F1142_HUMAN,tr|E7ESJ7|E7ESJ7_HUMAN" 2 1365.6958 1.33 138552 4951 2 1365.696569 683.8552 Protein FAM114A2 OS=Homo sapiens OX=9606 GN=FAM114A2 PE=1 SV=4 4.68 1474.5 - 199332 - - - 0.5345 - 2.885 0.634 - 1001.4 1 2 0 0.0007 12 0 0 0 1.32E+07 9.96E+06 - - - 6.5113 0.9999 221125_WJC_METTL3_EV_vs_WT_F10.04956.04956.3 2.09E-06 16/40 K.GPNK[136.11]HTLTQIK[136.11].D sp|P40227|TCPZ_HUMAN 1 1251.727 0.44 138556 4956 3 1251.727154 418.2496 T-complex protein 1 subunit zeta OS=Homo sapiens OX=9606 GN=CCT6A PE=1 SV=3 10 1474.9 - 4.64E+06 - - - 0.1071 - 3.024 0.518 - 407.4 1 2 1 0.0001 11 0 0 0 2.44E+07 5.58E+07 - - - 7.4588 0.9996 221125_WJC_METTL3_EV_vs_WT_F10.04963.04963.3 1.07E-06 15/52 K.LQAQVEC[160.03]SHSSQQR[166.11].Q sp|Q08378|GOGA3_HUMAN 1 1666.7721 -1 138563 4963 3 1666.764615 556.598 Golgin subfamily A member 3 OS=Homo sapiens OX=9606 GN=GOLGA3 PE=1 SV=2 6.74 1475.5 - 240353 - - - -4.4823 - 2.286 0.499 - 219.7 1 2 0 -0.0075 14 0 0 0 0.00E+00 0.00E+00 - - - 6.2985 0.8912 221125_WJC_METTL3_EV_vs_WT_F10.04964.04964.2 0.19 18-Jul T.RLGNDFHTNK.R "sp|P08708|RS17_HUMAN,tr|H0YN73|H0YN73_HUMAN,tr|H3BNC9|H3BNC9_HUMAN,tr|A0A0J9YYC4|A0A0J9YYC4_HUMAN,tr|H0YN88|H0YN88_HUMAN,tr|A0A075B716|A0A075B716_HUMAN" 6 1200.6 1.49 138564 4964 2 1200.600937 601.3073 40S ribosomal protein S17 OS=Homo sapiens OX=9606 GN=RPS17 PE=1 SV=2 8.75 1475.6 - 175164 - - - 0.8063 - 1.426 0.258 - 193.7 1 1 0 0.001 10 0 0 0 4.06E+06 2.72E+06 - - - 1.9368 1 221125_WJC_METTL3_EV_vs_WT_F10.04967.04967.3 2.44E-09 18/44 K.YHTINGHNAEVR[166.11].K "sp|P22626|ROA2_HUMAN,tr|A0A024RA28|A0A024RA28_HUMAN,tr|A0A7I2V4N1|A0A7I2V4N1_HUMAN,tr|A0A7I2V4I6|A0A7I2V4I6_HUMAN,tr|A0A087WUI2|A0A087WUI2_HUMAN,tr|A0A7I2V4S4|A0A7I2V4S4_HUMAN,tr|A0A7I2V323|A0A7I2V323_HUMAN,tr|A0A7I2V3P1|A0A7I2V3P1_HUMAN,tr|A0A7I2V3P7|A0A7I2V3P7_HUMAN" 9 1419.6883 1.33 138565 4967 3 1419.687195 474.2367 Heterogeneous nuclear ribonucleoproteins A2\B1 OS=Homo sapiens OX=9606 GN=HNRNPA2B1 PE=1 SV=2 6.92 1476.1 - 2.13E+07 - - - -0.7643 - 3.428 0.537 - 436.3 1 2 0 -0.0011 12 0 0 0 9.49E+08 7.14E+08 - - - 7.9416 0.9999 221125_WJC_METTL3_EV_vs_WT_F10.04974.04974.2 0.000363 16/18 R.RVEEDIQQQK.A sp|P15924|DESP_HUMAN 1 1271.647 122.8 138572 4974 2 1271.647478 636.8308 Desmoplakin OS=Homo sapiens OX=9606 GN=DSP PE=1 SV=3 4.68 1476.6 - 714268 - - - 0.3924 - 2.547 0.411 - 1118.4 1 2 0 0.0005 10 0 0 0 1.22E+07 9.95E+04 - - - 4.6861 0.8407 221125_WJC_METTL3_EV_vs_WT_F10.04976.04976.3 0.011 Jul-40 R.YLDEADR[166.11]DK[136.11]ER[166.11].Y "sp|Q9NP66|HM20A_HUMAN,tr|H0YKM5|H0YKM5_HUMAN" 2 1436.689 110.34 138574 4976 3 1436.685293 479.9036 High mobility group protein 20A OS=Homo sapiens OX=9606 GN=HMG20A PE=1 SV=1 4.44 1476.9 - 324974 - - - -2.5886 - 1.387 0.189 - 62.5 1 2 2 -0.0037 11 0 0 0 1.85E+08 1.68E+06 - - - 1.5755 0.9828 221125_WJC_METTL3_EV_vs_WT_F10.04980.04980.2 0.0015 14-Sep L.NGHNAEVR[166.11].K "sp|P22626|ROA2_HUMAN,tr|A0A024RA28|A0A024RA28_HUMAN,tr|A0A7I2V4N1|A0A7I2V4N1_HUMAN,tr|A0A7I2V4I6|A0A7I2V4I6_HUMAN,tr|A0A087WUI2|A0A087WUI2_HUMAN,tr|A0A7I2V4S4|A0A7I2V4S4_HUMAN,tr|A0A7I2V323|A0A7I2V323_HUMAN,tr|A0A7I2V3P1|A0A7I2V3P1_HUMAN,tr|A0A7I2V3P7|A0A7I2V3P7_HUMAN" 9 905.4343 1.42 138576 4980 2 905.433302 453.7244 Heterogeneous nuclear ribonucleoproteins A2\B1 OS=Homo sapiens OX=9606 GN=HNRNPA2B1 PE=1 SV=2 6.75 1477.4 - 5.13E+06 - - - -1.0989 - 1.676 0.445 - 299.8 1 1 0 -0.001 8 0 0 0 7.13E+07 5.01E+07 - - - 3.8849 1 221125_WJC_METTL3_EV_vs_WT_F10.04983.04983.3 5.37E-08 Dec-44 K.AHVQEVAQHNLK.E "sp|Q86UP2|KTN1_HUMAN,tr|G3V4Y7|G3V4Y7_HUMAN" 2 1372.7211 1.93 138579 4983 3 1372.719583 458.581 Kinectin OS=Homo sapiens OX=9606 GN=KTN1 PE=1 SV=1 6.96 1477.5 - 2.86E+06 - - - -1.1393 - 2.599 0.515 - 200.2 1 2 0 -0.0016 12 0 0 0 5.04E+07 2.61E+07 - - - 6.9288 1 221125_WJC_METTL3_EV_vs_WT_F10.04984.04984.2 3.39E-06 13/22 K.YHTINGHNAEVR.K "sp|P22626|ROA2_HUMAN,tr|A0A024RA28|A0A024RA28_HUMAN,tr|A0A7I2V4N1|A0A7I2V4N1_HUMAN,tr|A0A7I2V4I6|A0A7I2V4I6_HUMAN,tr|A0A087WUI2|A0A087WUI2_HUMAN,tr|A0A7I2V4S4|A0A7I2V4S4_HUMAN,tr|A0A7I2V323|A0A7I2V323_HUMAN,tr|A0A7I2V3P1|A0A7I2V3P1_HUMAN,tr|A0A7I2V3P7|A0A7I2V3P7_HUMAN" 9 1409.68 1.18 138580 4984 2 1409.684082 705.8473 Heterogeneous nuclear ribonucleoproteins A2\B1 OS=Homo sapiens OX=9606 GN=HNRNPA2B1 PE=1 SV=2 6.92 1477.6 - 2.44E+06 - - - 2.8886 - 2.463 0.605 - 514.4 1 2 0 0.0041 12 0 0 0 2.61E+07 2.21E+07 - - - 5.8799 0.9999 221125_WJC_METTL3_EV_vs_WT_F10.04986.04986.2 1.97E-07 13/22 K.YHTINGHNAEVR[166.11].K "sp|P22626|ROA2_HUMAN,tr|A0A024RA28|A0A024RA28_HUMAN,tr|A0A7I2V4N1|A0A7I2V4N1_HUMAN,tr|A0A7I2V4I6|A0A7I2V4I6_HUMAN,tr|A0A087WUI2|A0A087WUI2_HUMAN,tr|A0A7I2V4S4|A0A7I2V4S4_HUMAN,tr|A0A7I2V323|A0A7I2V323_HUMAN,tr|A0A7I2V3P1|A0A7I2V3P1_HUMAN,tr|A0A7I2V3P7|A0A7I2V3P7_HUMAN" 9 1419.6883 1.18 138582 4986 2 1419.686882 710.8514 Heterogeneous nuclear ribonucleoproteins A2\B1 OS=Homo sapiens OX=9606 GN=HNRNPA2B1 PE=1 SV=2 6.92 1477.8 - 1.92E+06 - - - -0.9847 - 2.508 0.569 - 472.2 1 2 0 -0.0014 12 0 0 0 2.61E+07 2.21E+07 - - - 5.6625 1 221125_WJC_METTL3_EV_vs_WT_F10.04987.04987.3 5.14E-07 Nov-44 K.AHVQEVAQHNLK[136.11].E "sp|Q86UP2|KTN1_HUMAN,tr|G3V4Y7|G3V4Y7_HUMAN" 2 1380.7353 1.93 138583 4987 3 1380.73373 461.2524 Kinectin OS=Homo sapiens OX=9606 GN=KTN1 PE=1 SV=1 6.96 1477.8 - 1.85E+06 - - - -1.1711 - 2.273 0.525 - 160.1 1 2 0 -0.0016 12 0 0 0 5.04E+07 2.61E+07 - - - 6.6687 0.9998 221125_WJC_METTL3_EV_vs_WT_F10.04989.04989.3 1.12E-07 16/52 K.IDGSNTVDHKNEIK.Q "sp|Q8IZH2|XRN1_HUMAN,tr|H7C5E4|H7C5E4_HUMAN" 2 1568.7794 0.75 138585 4989 3 1568.777402 523.9338 5'-3' exoribonuclease 1 OS=Homo sapiens OX=9606 GN=XRN1 PE=1 SV=1 5.38 1478.1 - 1.12E+06 - - - -1.3055 - 3.271 0.423 - 371.8 1 2 1 -0.002 14 0 0 0 9.52E+06 1.26E+07 - - - 6.4049 0.9908 221125_WJC_METTL3_EV_vs_WT_F10.04990.04990.3 2.51E-05 18/68 L.VSGLNSSASEPAK[136.11]EPAK[136.11]K[136.11].S "sp|Q86U44|MTA70_HUMAN,tr|F5H6D8|F5H6D8_HUMAN,tr|H0YFV6|H0YFV6_HUMAN,tr|B4DTN4|B4DTN4_HUMAN" 4 1822.9851 0.001 138586 4990 3 1822.982923 608.669 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 8.47 1478.2 - 838001 - - - -1.1898 - 3.115 0.528 - 271.1 1 1 1 -0.0022 18 0 0 0 0.00E+00 5.37E+06 - - - 7.2554 1 221125_WJC_METTL3_EV_vs_WT_F10.04992.04992.2 7.89E-08 16/18 H.TINGHNAEVR.K "sp|P22626|ROA2_HUMAN,tr|A0A024RA28|A0A024RA28_HUMAN,tr|A0A7I2V4N1|A0A7I2V4N1_HUMAN,tr|A0A7I2V4I6|A0A7I2V4I6_HUMAN,tr|A0A087WUI2|A0A087WUI2_HUMAN,tr|A0A7I2V4S4|A0A7I2V4S4_HUMAN,tr|A0A7I2V323|A0A7I2V323_HUMAN,tr|A0A7I2V3P1|A0A7I2V3P1_HUMAN,tr|A0A7I2V3P7|A0A7I2V3P7_HUMAN" 9 1109.5578 1.69 138588 4992 2 1109.555322 555.7862 Heterogeneous nuclear ribonucleoproteins A2\B1 OS=Homo sapiens OX=9606 GN=HNRNPA2B1 PE=1 SV=2 6.41 1478.4 - 537313 - - - -2.2063 - 2.368 0.648 - 789.4 1 1 0 -0.0024 10 0 0 0 5.60E+06 3.32E+06 - - - 6.2326 0.9968 221125_WJC_METTL3_EV_vs_WT_F10.04995.04995.3 5.21E-07 13/36 T.R[166.11]LGNDFHTNK[136.11].R "sp|P08708|RS17_HUMAN,tr|H0YN73|H0YN73_HUMAN,tr|H3BNC9|H3BNC9_HUMAN,tr|A0A0J9YYC4|A0A0J9YYC4_HUMAN,tr|H0YN88|H0YN88_HUMAN,tr|A0A075B716|A0A075B716_HUMAN" 6 1218.6224 1.44 138589 4995 3 1218.619543 407.2148 40S ribosomal protein S17 OS=Homo sapiens OX=9606 GN=RPS17 PE=1 SV=2 8.75 1478.8 - 7.32E+06 - - - -2.3765 - 2.541 0.583 - 299.6 1 1 0 -0.0029 10 0 0 0 1.15E+08 7.97E+07 - - - 7.7625 0.9917 221125_WJC_METTL3_EV_vs_WT_F10.04996.04996.2 5.30E-07 18-Dec H.TINGHNAEVR[166.11].K "sp|P22626|ROA2_HUMAN,tr|A0A024RA28|A0A024RA28_HUMAN,tr|A0A7I2V4N1|A0A7I2V4N1_HUMAN,tr|A0A7I2V4I6|A0A7I2V4I6_HUMAN,tr|A0A087WUI2|A0A087WUI2_HUMAN,tr|A0A7I2V4S4|A0A7I2V4S4_HUMAN,tr|A0A7I2V323|A0A7I2V323_HUMAN,tr|A0A7I2V3P1|A0A7I2V3P1_HUMAN,tr|A0A7I2V3P7|A0A7I2V3P7_HUMAN" 9 1119.566 1.69 138590 4996 2 1119.566728 560.7903 Heterogeneous nuclear ribonucleoproteins A2\B1 OS=Homo sapiens OX=9606 GN=HNRNPA2B1 PE=1 SV=2 6.41 1479 - 596702 - - - 0.6145 - 1.865 0.547 - 420.2 1 1 0 0.0007 10 0 0 0 5.60E+06 3.32E+06 - - - 4.8206 0.9859 221125_WJC_METTL3_EV_vs_WT_F10.04997.04997.2 0.000357 14-Aug L.NGHNAEVR.K "sp|P22626|ROA2_HUMAN,tr|A0A024RA28|A0A024RA28_HUMAN,tr|A0A7I2V4N1|A0A7I2V4N1_HUMAN,tr|A0A7I2V4I6|A0A7I2V4I6_HUMAN,tr|A0A087WUI2|A0A087WUI2_HUMAN,tr|A0A7I2V4S4|A0A7I2V4S4_HUMAN,tr|A0A7I2V323|A0A7I2V323_HUMAN,tr|A0A7I2V3P1|A0A7I2V3P1_HUMAN,tr|A0A7I2V3P7|A0A7I2V3P7_HUMAN" 9 895.426 1.42 138591 4997 2 895.425047 448.7203 Heterogeneous nuclear ribonucleoproteins A2\B1 OS=Homo sapiens OX=9606 GN=HNRNPA2B1 PE=1 SV=2 6.75 1479 - 1.23E+07 - - - -1.0945 - 1.688 0.477 - 294.4 1 1 0 -0.001 8 0 0 0 7.13E+07 5.01E+07 - - - 4.1428 0.91 221125_WJC_METTL3_EV_vs_WT_F10.04998.04998.2 0.195 16-Jul R.LRSEIDHVK.K "sp|P48668|K2C6C_HUMAN,sp|P04259|K2C6B_HUMAN,sp|P02538|K2C6A_HUMAN" 3 1095.6037 999 138592 4998 2 1095.604904 548.8091 "Keratin, type II cytoskeletal 6C OS=Homo sapiens OX=9606 GN=KRT6C PE=1 SV=3" 6.75 1479.1 - 352809 - - - 1.1382 - 1.346 0.142 - 160.4 1 2 1 0.0012 9 0 0 0 2.61E+06 0.00E+00 - - - 0.9491 0.998 221125_WJC_METTL3_EV_vs_WT_F10.05000.05000.2 4.00E-06 24-Dec K.TDEPGKYTADGGK.H sp|P31025|LCN1_HUMAN 1 1337.6099 999 138594 5000 2 1337.607845 669.8122 Lipocalin-1 OS=Homo sapiens OX=9606 GN=LCN1 PE=1 SV=1 4.56 1479.4 - 283896 - - - -1.555 - 2.073 0.555 - 533.6 1 2 1 -0.0021 13 0 0 0 3.04E+06 0.00E+00 - - - 5.0106 0.9999 221125_WJC_METTL3_EV_vs_WT_F10.05001.05001.2 2.15E-06 13/30 K.TGGTVESDGSTESTGR[166.11].L sp|Q8NDV7|TNR6A_HUMAN 1 1549.6731 -1 138595 5001 2 1549.672079 775.8438 Trinucleotide repeat-containing gene 6A protein OS=Homo sapiens OX=9606 GN=TNRC6A PE=1 SV=2 4.14 1479.5 - 244458 - - - -0.6866 - 2.165 0.64 - 565.7 1 2 0 -0.0011 16 0 0 0 0.00E+00 0.00E+00 - - - 5.6667 0.9995 221125_WJC_METTL3_EV_vs_WT_F10.05006.05006.3 0.000656 15/36 R.LRSEIDNVKK.Q sp|P04264|K2C1_HUMAN 1 1200.6826 3521.39 138598 5006 3 1200.681672 401.2348 "Keratin, type II cytoskeletal 1 OS=Homo sapiens OX=9606 GN=KRT1 PE=1 SV=6" 8.59 1480.1 - 8.85E+07 - - - -0.8029 - 2.705 0.325 - 400.5 1 2 1 -0.001 10 0 0 0 3.09E+09 8.79E+05 - - - 5.0693 0.9938 221125_WJC_METTL3_EV_vs_WT_F10.05008.05008.2 0.371 18-Oct R.LRSEIDNVKK.Q sp|P04264|K2C1_HUMAN 1 1200.6826 999 138600 5008 2 1200.681505 601.3486 "Keratin, type II cytoskeletal 1 OS=Homo sapiens OX=9606 GN=KRT1 PE=1 SV=6" 8.59 1480.2 - 4.80E+06 - - - -0.942 - 2.083 0.269 - 287.7 1 2 1 -0.0011 10 0 0 0 2.00E+08 0.00E+00 - - - 3.0758 0.9988 221125_WJC_METTL3_EV_vs_WT_F10.05009.05009.3 0.0359 Oct-32 K.R[166.11]VEEELEK[136.11]R[166.11].K sp|Q9NWB6|ARGL1_HUMAN 1 1214.6613 0.61 138601 5009 3 1214.659261 405.8944 Arginine and glutamate-rich protein 1 OS=Homo sapiens OX=9606 GN=ARGLU1 PE=1 SV=1 4.95 1480.2 - 1.77E+06 - - - -1.7116 - 2.039 0.251 - 217.1 1 2 0 -0.0021 9 0 0 0 1.03E+07 1.69E+07 - - - 3.485 0.9943 221125_WJC_METTL3_EV_vs_WT_F10.05011.05011.3 0.00142 14/48 K.NEETLREEEEEKK.Q sp|P82663|RT25_HUMAN 1 1661.7744 1.39 138603 5011 3 1661.771466 554.9321 "28S ribosomal protein S25, mitochondrial OS=Homo sapiens OX=9606 GN=MRPS25 PE=1 SV=1" 4.36 1480.4 - 818789 - - - -1.78 - 2.227 0.248 - 255.1 1 2 1 -0.003 13 0 0 0 1.54E+07 1.11E+07 - - - 3.4749 1 221125_WJC_METTL3_EV_vs_WT_F10.05012.05012.2 6.04E-05 30-Dec K.TGGTVESDGSTESTGR.L sp|Q8NDV7|TNR6A_HUMAN 1 1539.6649 3.72 138604 5012 2 1539.664606 770.8397 Trinucleotide repeat-containing gene 6A protein OS=Homo sapiens OX=9606 GN=TNRC6A PE=1 SV=2 4.14 1480.6 - 363187 - - - -0.1734 - 2.558 0.655 - 421.3 1 2 0 -0.0003 16 0 0 0 3.31E+06 8.90E+05 - - - 6.1879 0.9978 221125_WJC_METTL3_EV_vs_WT_F10.05014.05014.3 0.158 Aug-52 R.SSKPLAPNSNPPTK.D "sp|O60315|ZEB2_HUMAN,tr|U3KQ51|U3KQ51_HUMAN,tr|A0JP08|A0JP08_HUMAN,tr|A0A1B0GW50|A0A1B0GW50_HUMAN,tr|A0A1B0GV02|A0A1B0GV02_HUMAN,tr|A0A1B0GVV8|A0A1B0GVV8_HUMAN" 6 1436.7623 2.29 138606 5014 3 1436.762219 479.9281 Zinc finger E-box-binding homeobox 2 OS=Homo sapiens OX=9606 GN=ZEB2 PE=1 SV=1 10 1480.8 - 270916 - - - -0.0863 - 1.749 0.246 - 51.9 1 2 0 -0.0001 14 0 0 0 2.22E+07 9.73E+06 - - - 2.7683 0.901 221125_WJC_METTL3_EV_vs_WT_F10.05016.05016.2 0.0249 20-Jun Y.HTINGHNAEVR.K "sp|P22626|ROA2_HUMAN,tr|A0A024RA28|A0A024RA28_HUMAN,tr|A0A7I2V4N1|A0A7I2V4N1_HUMAN,tr|A0A7I2V4I6|A0A7I2V4I6_HUMAN,tr|A0A087WUI2|A0A087WUI2_HUMAN,tr|A0A7I2V4S4|A0A7I2V4S4_HUMAN,tr|A0A7I2V323|A0A7I2V323_HUMAN,tr|A0A7I2V3P1|A0A7I2V3P1_HUMAN,tr|A0A7I2V3P7|A0A7I2V3P7_HUMAN" 9 1246.6167 10.16 138608 5016 2 1246.616237 624.3156 Heterogeneous nuclear ribonucleoproteins A2\B1 OS=Homo sapiens OX=9606 GN=HNRNPA2B1 PE=1 SV=2 6.92 1481.1 - 206173 - - - -0.357 - 1.35 0.273 - 73.6 1 1 0 -0.0004 11 0 0 0 3.42E+06 3.36E+05 - - - 1.8691 1 221125_WJC_METTL3_EV_vs_WT_F10.05019.05019.3 2.21E-06 Dec-44 K.YHTINGHNAEVR.K "sp|P22626|ROA2_HUMAN,tr|A0A024RA28|A0A024RA28_HUMAN,tr|A0A7I2V4N1|A0A7I2V4N1_HUMAN,tr|A0A7I2V4I6|A0A7I2V4I6_HUMAN,tr|A0A087WUI2|A0A087WUI2_HUMAN,tr|A0A7I2V4S4|A0A7I2V4S4_HUMAN,tr|A0A7I2V323|A0A7I2V323_HUMAN,tr|A0A7I2V3P1|A0A7I2V3P1_HUMAN,tr|A0A7I2V3P7|A0A7I2V3P7_HUMAN" 9 1409.68 1.33 138610 5019 3 1409.680372 470.9006 Heterogeneous nuclear ribonucleoproteins A2\B1 OS=Homo sapiens OX=9606 GN=HNRNPA2B1 PE=1 SV=2 6.92 1481.4 - 3.66E+07 - - - 0.2568 - 2.637 0.546 - 208.2 1 2 0 0.0004 12 0 0 0 9.49E+08 7.14E+08 - - - 7.315 0.9998 221125_WJC_METTL3_EV_vs_WT_F10.05021.05021.3 4.59E-08 15/48 K.ISTTTSEEPC[160.03]R[166.11]DK[136.11].G sp|O15119|TBX3_HUMAN 1 1540.7158 0.92 138611 5021 3 1540.713233 514.5792 T-box transcription factor TBX3 OS=Homo sapiens OX=9606 GN=TBX3 PE=1 SV=4 4.68 1481.6 - 6.78E+06 - - - -1.6707 - 2.856 0.487 - 366.8 1 2 1 -0.0026 13 0 0 0 5.28E+07 5.74E+07 - - - 6.8141 0.9999 221125_WJC_METTL3_EV_vs_WT_F10.05022.05022.3 1.18E-05 14/48 K.ISTTTSEEPC[160.03]RDK.G sp|O15119|TBX3_HUMAN 1 1522.6933 0.91 138612 5022 3 1522.691171 508.5717 T-box transcription factor TBX3 OS=Homo sapiens OX=9606 GN=TBX3 PE=1 SV=4 4.68 1481.7 - 5.61E+06 - - - -1.4225 - 2.65 0.506 - 291.6 1 2 1 -0.0022 13 0 0 0 5.24E+07 5.74E+07 - - - 6.8231 0.9998 221125_WJC_METTL3_EV_vs_WT_F10.05023.05023.3 4.85E-06 Nov-48 K.TDEPGKYTADGGK.H sp|P31025|LCN1_HUMAN 1 1337.6099 6.44 138613 5023 3 1337.607324 446.8773 Lipocalin-1 OS=Homo sapiens OX=9606 GN=LCN1 PE=1 SV=1 4.56 1481.7 - 2.54E+06 - - - -1.9445 - 2.22 0.55 - 152 1 2 1 -0.0026 13 0 0 0 3.63E+07 5.64E+06 - - - 6.8335 0.9993 221125_WJC_METTL3_EV_vs_WT_F10.05024.05024.3 0.000442 Sep-48 K.NEETLR[166.11]EEEEEK[136.11]K[136.11].Q sp|P82663|RT25_HUMAN 1 1687.8111 1.39 138614 5024 3 1687.808335 563.611 "28S ribosomal protein S25, mitochondrial OS=Homo sapiens OX=9606 GN=MRPS25 PE=1 SV=1" 4.36 1481.8 - 2.43E+06 - - - -1.6347 - 1.933 0.43 - 104.4 1 2 1 -0.0028 13 0 0 0 1.54E+07 1.11E+07 - - - 5.1202 0.9997 221125_WJC_METTL3_EV_vs_WT_F10.05025.05025.3 0.00428 Nov-40 K.QVHPDTGISSK.A "sp|Q8N257|H2B3B_HUMAN,sp|P33778|H2B1B_HUMAN,sp|Q96A08|H2B1A_HUMAN,sp|Q5QNW6|H2B2F_HUMAN,sp|P58876|H2B1D_HUMAN,sp|Q99880|H2B1L_HUMAN,sp|P62807|H2B1C_HUMAN,sp|Q99877|H2B1N_HUMAN,sp|P57053|H2BFS_HUMAN,sp|P23527|H2B1O_HUMAN,sp|O60814|H2B1K_HUMAN,sp|Q93079|H2B1H_HUMAN,sp|Q99879|H2B1M_HUMAN,sp|Q16778|H2B2E_HUMAN,sp|P06899|H2B1J_HUMAN,tr|U3KQK0|U3KQK0_HUMAN" 16 1167.5884 1.21 138615 5025 3 1167.587013 390.2034 Histone H2B type 3-B OS=Homo sapiens OX=9606 GN=H2BU1 PE=1 SV=3 6.74 1481.8 - 2.40E+06 - - - -1.1888 - 2.166 0.316 - 139.1 1 2 0 -0.0014 11 0 0 0 1.52E+07 1.26E+07 - - - 4.2583 1 221125_WJC_METTL3_EV_vs_WT_F10.05029.05029.3 1.92E-08 19/52 R.QAGEVTYADAHKER.T "sp|Q13247|SRSF6_HUMAN,tr|A0A590UK80|A0A590UK80_HUMAN,tr|A0A590UJK4|A0A590UJK4_HUMAN,tr|A0A590UJP7|A0A590UJP7_HUMAN,tr|A0A590UK01|A0A590UK01_HUMAN" 5 1573.7485 1.56 138619 5029 3 1573.745959 525.5901 Serine\arginine-rich splicing factor 6 OS=Homo sapiens OX=9606 GN=SRSF6 PE=1 SV=2 5.45 1482.1 - 1.07E+06 - - - -1.6044 - 3.549 0.614 - 798 1 2 1 -0.0025 14 0 0 0 6.61E+06 4.24E+06 - - - 8.751 0.9999 221125_WJC_METTL3_EV_vs_WT_F10.05031.05031.3 1.52E-05 14/44 R.HLYHSSQNELAK[136.11].L sp|Q14789|GOGB1_HUMAN 1 1433.7143 2.01 138621 5031 3 1433.713069 478.912 Golgin subfamily B member 1 OS=Homo sapiens OX=9606 GN=GOLGB1 PE=1 SV=2 6.92 1482.4 - 629250 - - - -0.8426 - 2.44 0.405 - 194.2 1 2 0 -0.0012 12 0 0 0 9.88E+06 4.91E+06 - - - 5.5275 1 221125_WJC_METTL3_EV_vs_WT_F10.05034.05034.2 2.96E-07 24-Nov K.ISTTTSEEPC[160.03]R[166.11]DK[136.11].G sp|O15119|TBX3_HUMAN 1 1540.7158 1.15 138624 5034 2 1540.713474 771.3652 T-box transcription factor TBX3 OS=Homo sapiens OX=9606 GN=TBX3 PE=1 SV=4 4.68 1482.8 - 373309 - - - -1.5142 - 2.358 0.61 - 404.8 1 2 1 -0.0023 13 0 0 0 3.10E+06 2.68E+06 - - - 5.7473 1 221125_WJC_METTL3_EV_vs_WT_F10.05036.05036.3 0.00153 Dec-76 K.LEQASGASSSQEAGSSQAAK.E "sp|Q9BSV6|SEN34_HUMAN,tr|A0A590UJ73|A0A590UJ73_HUMAN,tr|E7EQB3|E7EQB3_HUMAN,tr|A0A0G2JNK5|A0A0G2JNK5_HUMAN,tr|A0A0G2JNL0|A0A0G2JNL0_HUMAN,tr|A0A590UJW4|A0A590UJW4_HUMAN,tr|B0V3J0|B0V3J0_HUMAN" 7 1892.8712 8.49 138626 5036 3 1892.869987 631.9643 tRNA-splicing endonuclease subunit Sen34 OS=Homo sapiens OX=9606 GN=TSEN34 PE=1 SV=1 4.53 1483 - 296056 - - - -0.6292 - 2.59 0.509 - 167.7 1 2 0 -0.0012 20 0 0 0 1.80E+06 2.12E+05 - - - 6.5233 1 221125_WJC_METTL3_EV_vs_WT_F10.05039.05039.3 2.18E-07 19/40 K.HLNSEHALDDR.S "sp|Q9H334|FOXP1_HUMAN,tr|A0A3B3ISQ6|A0A3B3ISQ6_HUMAN,tr|A0A3B3IRW5|A0A3B3IRW5_HUMAN,tr|G5E965|G5E965_HUMAN,tr|A0A3B3IRS5|A0A3B3IRS5_HUMAN,tr|A0A3B3IST0|A0A3B3IST0_HUMAN,tr|A0A3B3IT14|A0A3B3IT14_HUMAN,tr|C9J0F0|C9J0F0_HUMAN,tr|A0A3B3IUB6|A0A3B3IUB6_HUMAN,tr|H0Y882|H0Y882_HUMAN,tr|A0A3B3IT66|A0A3B3IT66_HUMAN,tr|A0A3B3IS87|A0A3B3IS87_HUMAN,tr|A0A0B4J2F3|A0A0B4J2F3_HUMAN,tr|A0A3B3IST6|A0A3B3IST6_HUMAN" 14 1305.6062 3.42 138627 5039 3 1305.603282 436.2093 Forkhead box protein P1 OS=Homo sapiens OX=9606 GN=FOXP1 PE=1 SV=1 5.21 1483.4 - 1.34E+07 - - - -2.2174 - 3.15 0.634 - 422.2 1 2 0 -0.0029 11 0 0 0 7.05E+07 2.06E+07 - - - 8.8672 0.999 221125_WJC_METTL3_EV_vs_WT_F10.05040.05040.2 0.136 14-Sep R.SEIDNVKK.Q sp|P04264|K2C1_HUMAN 1 931.4975 15.66 138628 5040 2 931.496003 466.756 "Keratin, type II cytoskeletal 1 OS=Homo sapiens OX=9606 GN=KRT1 PE=1 SV=6" 5.79 1483.5 - 3.94E+06 - - - -1.5652 - 1.813 0.27 - 364.3 1 2 0 -0.0015 8 0 0 0 1.95E+07 1.25E+06 - - - 2.8292 1 221125_WJC_METTL3_EV_vs_WT_F10.05041.05041.3 8.22E-09 19/40 K.HLNSEHALDDR[166.11].S "sp|Q9H334|FOXP1_HUMAN,tr|A0A3B3ISQ6|A0A3B3ISQ6_HUMAN,tr|A0A3B3IRW5|A0A3B3IRW5_HUMAN,tr|G5E965|G5E965_HUMAN,tr|A0A3B3IRS5|A0A3B3IRS5_HUMAN,tr|A0A3B3IST0|A0A3B3IST0_HUMAN,tr|A0A3B3IT14|A0A3B3IT14_HUMAN,tr|C9J0F0|C9J0F0_HUMAN,tr|A0A3B3IUB6|A0A3B3IUB6_HUMAN,tr|H0Y882|H0Y882_HUMAN,tr|A0A3B3IT66|A0A3B3IT66_HUMAN,tr|A0A3B3IS87|A0A3B3IS87_HUMAN,tr|A0A0B4J2F3|A0A0B4J2F3_HUMAN,tr|A0A3B3IST6|A0A3B3IST6_HUMAN" 14 1315.6144 3.42 138629 5041 3 1315.612129 439.5454 Forkhead box protein P1 OS=Homo sapiens OX=9606 GN=FOXP1 PE=1 SV=1 5.21 1483.6 - 3.82E+06 - - - -1.7619 - 3.273 0.628 - 451.1 1 2 0 -0.0023 11 0 0 0 7.05E+07 2.06E+07 - - - 8.9093 0.9997 221125_WJC_METTL3_EV_vs_WT_F10.05042.05042.3 0.0523 13/32 K.YK[136.11]AEDEVQR[166.11].E "sp|P0DMV8|HS71A_HUMAN,sp|P34931|HS71L_HUMAN,sp|P0DMV9|HS71B_HUMAN,tr|Q53FA3|Q53FA3_HUMAN,tr|V9GZ37|V9GZ37_HUMAN,tr|A0A0G2JIW1|A0A0G2JIW1_HUMAN" 6 1154.5687 0.01 138630 5042 3 1154.567058 385.8635 Heat shock 70 kDa protein 1A OS=Homo sapiens OX=9606 GN=HSPA1A PE=1 SV=1 4.68 1483.6 - 3.40E+06 - - - -1.3979 - 2.608 0.401 - 303.8 1 2 1 -0.0016 9 0 0 0 7.04E+05 5.38E+07 - - - 5.8993 1 221125_WJC_METTL3_EV_vs_WT_F10.05044.05044.3 5.98E-10 16/52 K.IEC[160.03]DDK[136.11]GDGSC[160.03]DVR[166.11].Y "sp|Q14315|FLNC_HUMAN,sp|P21333|FLNA_HUMAN,tr|A0A7P0NMY4|A0A7P0NMY4_HUMAN,tr|Q60FE5|Q60FE5_HUMAN" 4 1642.6682 1.21 138632 5044 3 1642.666017 548.5633 Filamin-C OS=Homo sapiens OX=9606 GN=FLNC PE=1 SV=3 4.04 1483.7 - 2.98E+06 - - - -1.332 - 3.543 0.738 - 303.2 1 2 1 -0.0022 14 0 0 0 2.97E+07 2.45E+07 - - - 10.1291 0.9979 221125_WJC_METTL3_EV_vs_WT_F10.05046.05046.3 1.44 16/48 R.LQEEEQK[136.11]K[136.11]EELAR[166.11].L sp|Q9ULW0|TPX2_HUMAN 1 1654.8736 0.71 138634 5046 3 1654.872304 552.6318 Targeting protein for Xklp2 OS=Homo sapiens OX=9606 GN=TPX2 PE=1 SV=2 4.65 1483.9 - 1.20E+06 - - - -0.8037 - 2.302 0.276 - 364.7 1 2 1 -0.0013 13 0 0 0 3.56E+06 4.98E+06 - - - 3.8774 0.9945 221125_WJC_METTL3_EV_vs_WT_F10.05047.05047.2 0.0233 16-Oct K.YK[136.11]AEDEVQR[166.11].E "sp|P0DMV8|HS71A_HUMAN,sp|P34931|HS71L_HUMAN,sp|P0DMV9|HS71B_HUMAN,tr|Q53FA3|Q53FA3_HUMAN,tr|V9GZ37|V9GZ37_HUMAN,tr|A0A0G2JIW1|A0A0G2JIW1_HUMAN" 6 1154.5687 0.08 138635 5047 2 1154.566381 578.2916 Heat shock 70 kDa protein 1A OS=Homo sapiens OX=9606 GN=HSPA1A PE=1 SV=1 4.68 1484 - 1.09E+06 - - - -1.9843 - 2.005 0.385 - 280.5 1 2 1 -0.0023 9 0 0 0 1.25E+06 1.52E+07 - - - 3.8964 1 221125_WJC_METTL3_EV_vs_WT_F10.05054.05054.2 8.37E-06 14/20 K.HLNSEHALDDR.S "sp|Q9H334|FOXP1_HUMAN,tr|A0A3B3ISQ6|A0A3B3ISQ6_HUMAN,tr|A0A3B3IRW5|A0A3B3IRW5_HUMAN,tr|G5E965|G5E965_HUMAN,tr|A0A3B3IRS5|A0A3B3IRS5_HUMAN,tr|A0A3B3IST0|A0A3B3IST0_HUMAN,tr|A0A3B3IT14|A0A3B3IT14_HUMAN,tr|C9J0F0|C9J0F0_HUMAN,tr|A0A3B3IUB6|A0A3B3IUB6_HUMAN,tr|H0Y882|H0Y882_HUMAN,tr|A0A3B3IT66|A0A3B3IT66_HUMAN,tr|A0A3B3IS87|A0A3B3IS87_HUMAN,tr|A0A0B4J2F3|A0A0B4J2F3_HUMAN,tr|A0A3B3IST6|A0A3B3IST6_HUMAN" 14 1305.6062 5.59 138642 5054 2 1305.604724 653.8104 Forkhead box protein P1 OS=Homo sapiens OX=9606 GN=FOXP1 PE=1 SV=1 5.21 1484.8 - 370654 - - - -1.1129 - 3.02 0.601 - 624 1 2 0 -0.0015 11 0 0 0 2.00E+06 3.58E+05 - - - 6.4695 1 221125_WJC_METTL3_EV_vs_WT_F10.05055.05055.2 1.72E-08 28-Dec R.QSGDGQESTEPVENK.V "sp|O15234|CASC3_HUMAN,tr|J3KSY7|J3KSY7_HUMAN" 2 1603.6962 3.91 138643 5055 2 1603.694538 802.8554 Protein CASC3 OS=Homo sapiens OX=9606 GN=CASC3 PE=1 SV=2 4 1485 - 275001 - - - -1.0195 - 2.432 0.699 - 339.6 1 2 0 -0.0016 15 0 0 0 2.84E+06 7.27E+05 - - - 6.3882 1 221125_WJC_METTL3_EV_vs_WT_F10.05059.05059.3 1.37E-07 14/52 K.IEC[160.03]DDKGDGSC[160.03]DVR.Y "sp|Q14315|FLNC_HUMAN,sp|P21333|FLNA_HUMAN,tr|A0A7P0NMY4|A0A7P0NMY4_HUMAN,tr|Q60FE5|Q60FE5_HUMAN" 4 1624.6457 1.21 138645 5059 3 1624.645411 542.5559 Filamin-C OS=Homo sapiens OX=9606 GN=FLNC PE=1 SV=3 4.04 1485.5 - 7.22E+06 - - - -0.1994 - 2.604 0.719 - 277.7 1 2 1 -0.0003 14 0 0 0 2.97E+07 2.45E+07 - - - 9.0994 0.9998 221125_WJC_METTL3_EV_vs_WT_F10.05060.05060.3 0.00211 14/32 R.K[136.11]FEQLK[136.11]QER[166.11].L "sp|Q13310|PABP4_HUMAN,tr|A0A7I2V5W9|A0A7I2V5W9_HUMAN,tr|H0YEU6|H0YEU6_HUMAN,tr|B1ANR0|B1ANR0_HUMAN,tr|A0A7I2V4L7|A0A7I2V4L7_HUMAN,tr|A0A7I2V598|A0A7I2V598_HUMAN,tr|H0Y5F5|H0Y5F5_HUMAN" 7 1230.6931 1.31 138646 5060 3 1230.691453 411.2383 Polyadenylate-binding protein 4 OS=Homo sapiens OX=9606 GN=PABPC4 PE=1 SV=1 8.59 1485.5 - 7.40E+06 - - - -1.331 - 2.664 0.427 - 275.9 1 2 1 -0.0016 9 0 0 0 3.58E+07 2.72E+07 - - - 6.2532 0.999 221125_WJC_METTL3_EV_vs_WT_F10.05061.05061.3 0.00207 Nov-40 R.K[136.11]LEEEEDGK[136.11]LK[136.11].K "sp|P11387|TOP1_HUMAN,tr|A0A7P0T9R7|A0A7P0T9R7_HUMAN" 2 1340.725 0.6 138647 5061 3 1340.724314 447.9156 DNA topoisomerase 1 OS=Homo sapiens OX=9606 GN=TOP1 PE=1 SV=2 4.59 1485.6 - 2.81E+06 - - - -0.4826 - 2.048 0.355 - 162.8 1 2 1 -0.0006 11 0 0 0 8.02E+06 1.34E+07 - - - 4.5342 1 221125_WJC_METTL3_EV_vs_WT_F10.05062.05062.3 3.28E-06 18/52 R.R[166.11]PEGPGAQAPSSPR[166.11].V sp|P40222|TXLNA_HUMAN 1 1425.7228 1.17 138648 5062 3 1425.724002 476.2482 Alpha-taxilin OS=Homo sapiens OX=9606 GN=TXLNA PE=1 SV=3 9.6 1485.6 - 2.42E+06 - - - 0.8676 - 3.205 0.503 - 422.5 1 2 0 0.0012 14 0 0 0 3.20E+07 2.72E+07 - - - 7.2429 0.9992 221125_WJC_METTL3_EV_vs_WT_F10.05064.05064.3 0.00235 Oct-44 K.MIASDSHR[166.11]PEVK[136.11].L "sp|Q9NYF8|BCLF1_HUMAN,tr|E9PKI6|E9PKI6_HUMAN,tr|A0A1W2PQ43|A0A1W2PQ43_HUMAN,tr|E9PK91|E9PK91_HUMAN,tr|E9PJA7|E9PJA7_HUMAN,tr|E9PK09|E9PK09_HUMAN,tr|E9PQN2|E9PQN2_HUMAN" 7 1386.7045 2.28 138650 5064 3 1386.706715 463.2421 Bcl-2-associated transcription factor 1 OS=Homo sapiens OX=9606 GN=BCLAF1 PE=1 SV=2 6.51 1485.7 - 1.62E+06 - - - 1.6305 - 2.052 0.291 - 103.3 1 2 0 0.0023 12 0 0 0 1.45E+08 6.35E+07 - - - 3.7762 1 221125_WJC_METTL3_EV_vs_WT_F10.05065.05065.3 0.00471 16/52 K.EGDLAGHDMGHESK.R sp|Q9UI36|DACH1_HUMAN 1 1481.6205 2.68 138651 5065 3 1481.618307 494.8808 Dachshund homolog 1 OS=Homo sapiens OX=9606 GN=DACH1 PE=1 SV=4 4.72 1485.8 - 1.46E+06 - - - -1.4842 - 2.805 0.481 - 385.1 1 2 0 -0.0022 14 0 0 0 1.30E+07 4.85E+06 - - - 6.6431 0.9996 221125_WJC_METTL3_EV_vs_WT_F10.05069.05069.3 0.000581 14/48 R.VK[136.11]PDVVQDK[136.11]ETER[166.11].N sp|Q9Y3B9|RRP15_HUMAN 1 1567.8416 1.19 138655 5069 3 1567.842938 523.6211 RRP15-like protein OS=Homo sapiens OX=9606 GN=RRP15 PE=1 SV=2 4.78 1486.2 - 823099 - - - 0.8496 - 2.519 0.397 - 146.9 1 2 1 0.0013 13 0 0 0 1.04E+07 8.72E+06 - - - 5.4706 0.9914 221125_WJC_METTL3_EV_vs_WT_F10.05072.05072.2 0.00101 16-Sep K.YKAEDEVQR.E "sp|P0DMV8|HS71A_HUMAN,sp|P34931|HS71L_HUMAN,sp|P0DMV9|HS71B_HUMAN,tr|Q53FA3|Q53FA3_HUMAN,tr|V9GZ37|V9GZ37_HUMAN,tr|A0A0G2JIW1|A0A0G2JIW1_HUMAN" 6 1136.5462 -1 138658 5072 2 1136.547496 569.2804 Heat shock 70 kDa protein 1A OS=Homo sapiens OX=9606 GN=HSPA1A PE=1 SV=1 4.68 1486.4 - 438753 - - - 1.1385 - 1.815 0.294 - 199.7 1 2 1 0.0013 9 0 0 0 0.00E+00 0.00E+00 - - - 2.9366 0.9986 221125_WJC_METTL3_EV_vs_WT_F10.05074.05074.2 0.000179 28-May R.QSGDGQESTEPVENK[136.11].V "sp|O15234|CASC3_HUMAN,tr|J3KSY7|J3KSY7_HUMAN" 2 1611.7104 -1 138660 5074 2 1611.706196 806.8625 Protein CASC3 OS=Homo sapiens OX=9606 GN=CASC3 PE=1 SV=2 4 1486.7 - 206610 - - - -2.5917 - 1.25 0.485 - 57.8 1 2 0 -0.0042 15 0 0 0 0.00E+00 0.00E+00 - - - 3.1705 0.9932 221125_WJC_METTL3_EV_vs_WT_F10.05075.05075.2 0.00255 26-Jun K.IEC[160.03]DDK[136.11]GDGSC[160.03]DVR[166.11].Y "sp|Q14315|FLNC_HUMAN,sp|P21333|FLNA_HUMAN,tr|A0A7P0NMY4|A0A7P0NMY4_HUMAN,tr|Q60FE5|Q60FE5_HUMAN" 4 1642.6682 -1 138661 5075 2 1642.665504 822.3414 Filamin-C OS=Homo sapiens OX=9606 GN=FLNC PE=1 SV=3 4.04 1486.8 - 168495 - - - -1.6443 - 1.317 0.492 - 90 1 2 1 -0.0027 14 0 0 0 0.00E+00 0.00E+00 - - - 3.3651 1 221125_WJC_METTL3_EV_vs_WT_F10.05079.05079.3 5.39E-07 18/48 R.AFHNEAQVNPER[166.11]K[136.11].N "sp|P17987|TCPA_HUMAN,tr|F5H282|F5H282_HUMAN,tr|E7EQR6|E7EQR6_HUMAN" 3 1556.7815 0.45 138663 5079 3 1556.782302 519.9344 T-complex protein 1 subunit alpha OS=Homo sapiens OX=9606 GN=TCP1 PE=1 SV=1 6.8 1487.3 - 1.12E+07 - - - 0.5415 - 3.028 0.527 - 573.3 1 2 0 0.0008 13 0 0 0 6.15E+07 1.36E+08 - - - 7.4191 1 221125_WJC_METTL3_EV_vs_WT_F10.05080.05080.3 8.27E-09 17/48 R.AFHNEAQVNPERK.N "sp|P17987|TCPA_HUMAN,tr|F5H282|F5H282_HUMAN,tr|E7EQR6|E7EQR6_HUMAN" 3 1538.759 0.45 138664 5080 3 1538.760234 513.9269 T-complex protein 1 subunit alpha OS=Homo sapiens OX=9606 GN=TCP1 PE=1 SV=1 6.8 1487.4 - 4.94E+06 - - - 0.8091 - 3.279 0.513 - 474.2 1 2 0 0.0012 13 0 0 0 6.14E+07 1.36E+08 - - - 7.4789 0.9979 221125_WJC_METTL3_EV_vs_WT_F10.05081.05081.3 0.0352 14/36 K.RRQDSLESMK.F sp|P15924|DESP_HUMAN 1 1248.6245 2.22 138665 5081 3 1248.624511 417.2154 Desmoplakin OS=Homo sapiens OX=9606 GN=DSP PE=1 SV=3 8.75 1487.4 - 2.94E+06 - - - 0.0336 - 1.96 0.304 - 415.4 1 2 1 0 10 0 0 0 1.45E+07 6.54E+06 - - - 3.8946 0.9991 221125_WJC_METTL3_EV_vs_WT_F10.05083.05083.3 0.00315 Oct-44 R.ANVVTTPSTNRK.N "sp|Q8IWZ3|ANKH1_HUMAN,tr|E9PDP5|E9PDP5_HUMAN,tr|H0Y472|H0Y472_HUMAN,tr|H0Y4P6|H0Y4P6_HUMAN,tr|H0Y785|H0Y785_HUMAN" 5 1286.6943 1.5 138667 5083 3 1286.696124 429.9054 Ankyrin repeat and KH domain-containing protein 1 OS=Homo sapiens OX=9606 GN=ANKHD1 PE=1 SV=1 11 1487.6 - 1.39E+06 - - - 1.4463 - 1.882 0.296 - 159.8 1 2 0 0.0019 12 0 0 0 1.52E+07 1.01E+07 - - - 3.5923 0.9999 221125_WJC_METTL3_EV_vs_WT_F10.05084.05084.3 0.000147 Aug-52 K.EGDLAGHDMGHESK[136.11].R sp|Q9UI36|DACH1_HUMAN 1 1489.6347 2.68 138668 5084 3 1489.635161 497.5522 Dachshund homolog 1 OS=Homo sapiens OX=9606 GN=DACH1 PE=1 SV=4 4.72 1487.6 - 1.38E+06 - - - 0.3054 - 1.898 0.431 - 77.2 1 2 0 0.0005 14 0 0 0 1.30E+07 4.85E+06 - - - 5.048 0.9992 221125_WJC_METTL3_EV_vs_WT_F10.05085.05085.3 0.00528 Oct-52 R.SSK[136.11]PLAPNSNPPTK[136.11].D "sp|O60315|ZEB2_HUMAN,tr|U3KQ51|U3KQ51_HUMAN,tr|A0JP08|A0JP08_HUMAN,tr|A0A1B0GW50|A0A1B0GW50_HUMAN,tr|A0A1B0GV02|A0A1B0GV02_HUMAN,tr|A0A1B0GVV8|A0A1B0GVV8_HUMAN" 6 1452.7907 2.37 138669 5085 3 1452.792105 485.2709 Zinc finger E-box-binding homeobox 2 OS=Homo sapiens OX=9606 GN=ZEB2 PE=1 SV=1 10 1487.7 - 1.05E+06 - - - 0.9375 - 1.731 0.316 - 120.7 1 2 0 0.0014 14 0 0 0 2.34E+07 9.89E+06 - - - 3.5209 0.9999 221125_WJC_METTL3_EV_vs_WT_F10.05086.05086.3 0.000897 Dec-52 K.QGINEDQEESQK[136.11]PR[166.11].L "sp|Q8TBZ6|TM10A_HUMAN,tr|D6R954|D6R954_HUMAN,tr|X6REK4|X6REK4_HUMAN" 3 1674.7928 0.74 138670 5086 3 1674.79293 559.2715 tRNA methyltransferase 10 homolog A OS=Homo sapiens OX=9606 GN=TRMT10A PE=1 SV=1 4.41 1487.7 - 1.04E+06 - - - 0.0711 - 2.155 0.415 - 190.4 1 2 0 0.0001 14 0 0 0 3.34E+06 4.54E+06 - - - 5.2072 0.9998 221125_WJC_METTL3_EV_vs_WT_F10.05087.05087.3 0.000224 Aug-44 R.VDC[160.03]DQHSDIAQR.Y sp|Q9BS26|ERP44_HUMAN 1 1442.6208 0.56 138671 5087 3 1442.622709 481.8809 Endoplasmic reticulum resident protein 44 OS=Homo sapiens OX=9606 GN=ERP44 PE=1 SV=1 4.41 1487.8 - 941035 - - - 1.2949 - 1.673 0.455 - 98.6 1 2 0 0.0019 12 0 0 0 5.60E+06 9.98E+06 - - - 5.0387 0.9997 221125_WJC_METTL3_EV_vs_WT_F10.05089.05089.2 0.00441 18-Sep R.K[136.11]IEVNNATAR[166.11].V "sp|O43251|RFOX2_HUMAN,sp|Q9NWB1|RFOX1_HUMAN,sp|A6NFN3|RFOX3_HUMAN,tr|A0A6Q8PGE0|A0A6Q8PGE0_HUMAN,tr|A0A6Q8PH77|A0A6Q8PH77_HUMAN,tr|A0A286YEU2|A0A286YEU2_HUMAN,tr|A0A087X2B1|A0A087X2B1_HUMAN,tr|F8VR27|F8VR27_HUMAN,tr|B7Z1U7|B7Z1U7_HUMAN,tr|B0QYV1|B0QYV1_HUMAN,tr|A0A6Q8PHA3|A0A6Q8PHA3_HUMAN,tr|A0A3B3ITL7|A0A3B3ITL7_HUMAN,tr|F8VZY7|F8VZY7_HUMAN,tr|B0QYY4|B0QYY4_HUMAN,tr|J3KNW3|J3KNW3_HUMAN,tr|F8VZG9|F8VZG9_HUMAN,tr|J3QRF4|J3QRF4_HUMAN,tr|F8VRS4|F8VRS4_HUMAN,tr|A0A6Q8PFM4|A0A6Q8PFM4_HUMAN,tr|S4R469|S4R469_HUMAN,tr|A0A804HKG7|A0A804HKG7_HUMAN,tr|A0A0G2JRD1|A0A0G2JRD1_HUMAN,tr|A0A0G2JRA5|A0A0G2JRA5_HUMAN,tr|A0A804HJM2|A0A804HJM2_HUMAN,tr|I3L1D4|I3L1D4_HUMAN,tr|S4R3K7|S4R3K7_HUMAN" 26 1132.6319 1.43 138673 5089 2 1132.632255 567.3232 RNA binding protein fox-1 homolog 2 OS=Homo sapiens OX=9606 GN=RBFOX2 PE=1 SV=3 8.75 1488 - 498688 - - - 0.2772 - 1.861 0.372 - 275.7 1 2 0 0.0003 10 0 0 0 3.46E+06 2.43E+06 - - - 3.5222 0.9853 221125_WJC_METTL3_EV_vs_WT_F10.05090.05090.2 0.00459 18-Dec L.ASDSHR[166.11]PEVK[136.11].L "sp|Q9NYF8|BCLF1_HUMAN,tr|E9PKI6|E9PKI6_HUMAN,tr|A0A1W2PQ43|A0A1W2PQ43_HUMAN,tr|E9PK91|E9PK91_HUMAN,tr|E9PJA7|E9PJA7_HUMAN,tr|E9PK09|E9PK09_HUMAN,tr|E9PQN2|E9PQN2_HUMAN" 7 1142.5799 2.96 138674 5090 2 1142.581914 572.2972 Bcl-2-associated transcription factor 1 OS=Homo sapiens OX=9606 GN=BCLAF1 PE=1 SV=2 6.8 1488.1 - 325326 - - - 1.7583 - 2.294 0.466 - 489.5 1 1 0 0.002 10 0 0 0 1.35E+07 4.55E+06 - - - 4.7999 0.9573 221125_WJC_METTL3_EV_vs_WT_F10.05091.05091.3 2.90E-05 Nov-44 A.FHNEAQVNPERK.N "sp|P17987|TCPA_HUMAN,tr|F5H282|F5H282_HUMAN,tr|E7EQR6|E7EQR6_HUMAN" 3 1467.7219 0.34 138675 5091 3 1467.715179 490.2479 T-complex protein 1 subunit alpha OS=Homo sapiens OX=9606 GN=TCP1 PE=1 SV=1 6.76 1488.2 - 299891 - - - -4.5622 - 2.257 0.492 - 170.9 1 1 0 -0.0067 12 0 0 0 2.43E+06 7.08E+06 - - - 6.2798 0.9999 221125_WJC_METTL3_EV_vs_WT_F10.05092.05092.2 1.41E-05 Aug-36 K.AGGTDAPSANGEAGGESTK[136.11].G "sp|Q9NXW2|DJB12_HUMAN,tr|J3KPS0|J3KPS0_HUMAN" 2 1683.7427 1.25 138676 5092 2 1683.744618 842.8786 DnaJ homolog subfamily B member 12 OS=Homo sapiens OX=9606 GN=DNAJB12 PE=1 SV=5 4.14 1488.4 - 288714 - - - 1.1177 - 1.952 0.622 - 99.1 1 2 0 0.0019 19 0 0 0 2.06E+06 1.65E+06 - - - 5.2789 1 221125_WJC_METTL3_EV_vs_WT_F10.05093.05093.2 3.66E-06 24-Nov R.AFHNEAQVNPER[166.11]K[136.11].N "sp|P17987|TCPA_HUMAN,tr|F5H282|F5H282_HUMAN,tr|E7EQR6|E7EQR6_HUMAN" 3 1556.7815 0.32 138677 5093 2 1556.784799 779.398 T-complex protein 1 subunit alpha OS=Homo sapiens OX=9606 GN=TCP1 PE=1 SV=1 6.8 1488.5 - 210555 - - - 2.1455 - 2.524 0.587 - 356.7 1 2 0 0.0033 13 0 0 0 7.49E+05 2.32E+06 - - - 5.7517 0.9999 221125_WJC_METTL3_EV_vs_WT_F10.05096.05096.4 0.000267 14/72 R.AFHNEAQVNPERK.N "sp|P17987|TCPA_HUMAN,tr|F5H282|F5H282_HUMAN,tr|E7EQR6|E7EQR6_HUMAN" 3 1538.759 0.44 138678 5096 4 1538.760046 385.697 T-complex protein 1 subunit alpha OS=Homo sapiens OX=9606 GN=TCP1 PE=1 SV=1 6.8 1488.9 - 1.28E+07 - - - 0.6869 - 2.718 0.464 - 199.5 1 2 0 0.0011 13 0 0 0 8.81E+07 2.02E+08 - - - 3.6351 0.9998 221125_WJC_METTL3_EV_vs_WT_F10.05098.05098.3 1.59E-05 14/40 K.ASFIK[136.11]DEGK[136.11]DK[136.11].A sp|O00566|MPP10_HUMAN 1 1260.6776 1.48 138680 5098 3 1260.677522 421.2331 U3 small nucleolar ribonucleoprotein protein MPP10 OS=Homo sapiens OX=9606 GN=MPHOSPH10 PE=1 SV=2 6.16 1489 - 2.62E+06 - - - -0.0754 - 2.594 0.448 - 305.1 1 2 2 -0.0001 11 0 0 0 3.51E+07 2.37E+07 - - - 6.2426 0.9999 221125_WJC_METTL3_EV_vs_WT_F10.05099.05099.3 0.00059 Nov-40 R.VYTDVNTHRPR.E "sp|P68400|CSK21_HUMAN,sp|Q8NEV1|CSK23_HUMAN,tr|A0A2R8YCK2|A0A2R8YCK2_HUMAN,tr|A0A2R8YFU2|A0A2R8YFU2_HUMAN,tr|V9GYA2|V9GYA2_HUMAN,tr|A0A2R8YEW1|A0A2R8YEW1_HUMAN,tr|A0A2R8Y4D6|A0A2R8Y4D6_HUMAN,tr|A0A2R8YD58|A0A2R8YD58_HUMAN,tr|A0A2R8YF43|A0A2R8YF43_HUMAN,tr|A0A2R8Y5A0|A0A2R8Y5A0_HUMAN,tr|A0A2R8YDY7|A0A2R8YDY7_HUMAN,tr|A0A2R8YF47|A0A2R8YF47_HUMAN,tr|A0A2R8Y4H0|A0A2R8Y4H0_HUMAN,tr|A0A2R8Y7T1|A0A2R8Y7T1_HUMAN,tr|A0A2R8YDP2|A0A2R8YDP2_HUMAN,tr|A0A2R8Y797|A0A2R8Y797_HUMAN,tr|A0A2R8YEL7|A0A2R8YEL7_HUMAN,tr|V9GY80|V9GY80_HUMAN,tr|A0A2R8YCC9|A0A2R8YCC9_HUMAN,tr|E7EU96|E7EU96_HUMAN,tr|A0A2R8Y3W6|A0A2R8Y3W6_HUMAN" 21 1356.6898 0.48 138681 5099 3 1356.689679 453.2372 Casein kinase II subunit alpha OS=Homo sapiens OX=9606 GN=CSNK2A1 PE=1 SV=1 8.72 1489.1 - 2.36E+06 - - - -0.1238 - 2.06 0.475 - 166.5 1 2 0 -0.0002 11 0 0 0 9.97E+06 2.06E+07 - - - 5.8888 0.9998 221125_WJC_METTL3_EV_vs_WT_F10.05100.05100.3 0.00199 Nov-36 K.DSDLSHVQNK.S "sp|O60506|HNRPQ_HUMAN,tr|A0A7I2YQV8|A0A7I2YQV8_HUMAN,tr|A0A7I2YQN2|A0A7I2YQN2_HUMAN,tr|A0A7I2V5Q6|A0A7I2V5Q6_HUMAN,tr|A0A7I2V4Z0|A0A7I2V4Z0_HUMAN,tr|A0A7I2V4J0|A0A7I2V4J0_HUMAN,tr|F6UXX1|F6UXX1_HUMAN,tr|A0A7I2V346|A0A7I2V346_HUMAN" 8 1141.5364 1.23 138682 5100 3 1141.537635 381.5194 Heterogeneous nuclear ribonucleoprotein Q OS=Homo sapiens OX=9606 GN=SYNCRIP PE=1 SV=2 5.21 1489.1 - 1.54E+06 - - - 1.1117 - 2.07 0.364 - 161 1 2 0 0.0013 10 0 0 0 1.00E+07 8.15E+06 - - - 4.7226 0.9982 221125_WJC_METTL3_EV_vs_WT_F10.05101.05101.3 0.0496 Oct-44 R.ANVVTTPSTNR[166.11]K[136.11].N "sp|Q8IWZ3|ANKH1_HUMAN,tr|E9PDP5|E9PDP5_HUMAN,tr|H0Y472|H0Y472_HUMAN,tr|H0Y4P6|H0Y4P6_HUMAN,tr|H0Y785|H0Y785_HUMAN" 5 1304.7167 1.5 138683 5101 3 1304.717029 435.9129 Ankyrin repeat and KH domain-containing protein 1 OS=Homo sapiens OX=9606 GN=ANKHD1 PE=1 SV=1 11 1489.2 - 899304 - - - 0.2269 - 2.02 0.216 - 143.3 1 2 0 0.0003 12 0 0 0 1.52E+07 1.01E+07 - - - 2.897 0.9905 221125_WJC_METTL3_EV_vs_WT_F10.05102.05102.2 0.000184 16-Dec A.SDSHRPEVK.L "sp|Q9NYF8|BCLF1_HUMAN,tr|E9PKI6|E9PKI6_HUMAN,tr|A0A1W2PQ43|A0A1W2PQ43_HUMAN,tr|E9PK91|E9PK91_HUMAN,tr|E9PJA7|E9PJA7_HUMAN,tr|E9PK09|E9PK09_HUMAN,tr|E9PQN2|E9PQN2_HUMAN" 7 1053.5203 2.55 138684 5102 2 1053.520561 527.7674 Bcl-2-associated transcription factor 1 OS=Homo sapiens OX=9606 GN=BCLAF1 PE=1 SV=2 6.47 1489.3 - 726388 - - - 0.2269 - 2.296 0.405 - 692.7 1 1 0 0.0002 9 0 0 0 5.29E+06 2.07E+06 - - - 4.4369 0.9998 221125_WJC_METTL3_EV_vs_WT_F10.05103.05103.3 3.16E-05 Oct-32 R.DR[166.11]YDSDR[166.11]YR[166.11].D "sp|P23588|IF4B_HUMAN,tr|E7EX17|E7EX17_HUMAN,tr|F8VX11|F8VX11_HUMAN" 3 1274.5782 2 138685 5103 3 1274.576958 425.8667 Eukaryotic translation initiation factor 4B OS=Homo sapiens OX=9606 GN=EIF4B PE=1 SV=2 6.04 1489.4 - 724469 - - - -0.9925 - 1.913 0.483 - 209.5 1 2 2 -0.0013 9 0 0 0 1.10E+07 5.50E+06 - - - 5.8796 0.9935 221125_WJC_METTL3_EV_vs_WT_F10.05108.05108.2 0.558 22-Jun R.ANVVTTPSTNRK.N "sp|Q8IWZ3|ANKH1_HUMAN,tr|E9PDP5|E9PDP5_HUMAN,tr|H0Y472|H0Y472_HUMAN,tr|H0Y4P6|H0Y4P6_HUMAN,tr|H0Y785|H0Y785_HUMAN" 5 1286.6943 1.42 138690 5108 2 1286.694808 644.3544 Ankyrin repeat and KH domain-containing protein 1 OS=Homo sapiens OX=9606 GN=ANKHD1 PE=1 SV=1 11 1490 - 136665 - - - 0.4236 - 1.31 0.182 - 44.5 2 2 0 0.0005 12 0 0 0 8.53E+05 6.01E+05 - - - 0.9611 0.9994 221125_WJC_METTL3_EV_vs_WT_F10.05112.05112.3 0.0231 13/40 K.ASFIKDEGKDK.A sp|O00566|MPP10_HUMAN 1 1236.635 1.56 138692 5112 3 1236.634548 413.2189 U3 small nucleolar ribonucleoprotein protein MPP10 OS=Homo sapiens OX=9606 GN=MPHOSPH10 PE=1 SV=2 6.16 1490.5 - 7.20E+06 - - - -0.3793 - 2.25 0.37 - 216.1 1 2 2 -0.0005 11 0 0 0 3.46E+07 2.21E+07 - - - 4.9687 0.9972 221125_WJC_METTL3_EV_vs_WT_F10.05114.05114.3 0.0012 13/36 K.EHELLEQQKR.A "sp|Q13435|SF3B2_HUMAN,tr|H0YCG1|H0YCG1_HUMAN,tr|E9PJ04|E9PJ04_HUMAN,tr|E9PJT3|E9PJT3_HUMAN" 4 1308.6786 0.99 138694 5114 3 1308.679578 437.2335 Splicing factor 3B subunit 2 OS=Homo sapiens OX=9606 GN=SF3B2 PE=1 SV=2 5.5 1490.6 - 2.18E+06 - - - 0.7374 - 2.346 0.142 - 422.4 1 2 0 0.001 10 0 0 0 1.01E+07 1.03E+07 - - - 2.6132 0.9997 221125_WJC_METTL3_EV_vs_WT_F10.05115.05115.3 0.0111 Oct-36 R.KFHEAQLSEK.L "sp|O75694|NU155_HUMAN,tr|E9PF10|E9PF10_HUMAN" 2 1215.6248 1.14 138695 5115 3 1215.624607 406.2155 Nuclear pore complex protein Nup155 OS=Homo sapiens OX=9606 GN=NUP155 PE=1 SV=1 6.76 1490.6 - 1.81E+06 - - - -0.1481 - 2.036 0.334 - 146.3 1 2 0 -0.0002 10 0 0 0 6.94E+06 6.11E+06 - - - 4.3401 0.9997 221125_WJC_METTL3_EV_vs_WT_F10.05116.05116.3 0.00028 Dec-32 R.DRYDSDRYR.D "sp|P23588|IF4B_HUMAN,tr|E7EX17|E7EX17_HUMAN,tr|F8VX11|F8VX11_HUMAN" 3 1244.5534 1.68 138696 5116 3 1244.553246 415.8584 Eukaryotic translation initiation factor 4B OS=Homo sapiens OX=9606 GN=EIF4B PE=1 SV=2 6.04 1490.7 - 1.67E+06 - - - -0.1342 - 2.297 0.405 - 331.9 1 2 2 -0.0002 9 0 0 0 9.25E+06 5.50E+06 - - - 5.5616 0.9897 221125_WJC_METTL3_EV_vs_WT_F10.05118.05118.3 0.00078 Nov-44 A.FHNEAQVNPER[166.11]K[136.11].N "sp|P17987|TCPA_HUMAN,tr|F5H282|F5H282_HUMAN,tr|E7EQR6|E7EQR6_HUMAN" 3 1485.7443 0.37 138698 5118 3 1485.743412 496.2554 T-complex protein 1 subunit alpha OS=Homo sapiens OX=9606 GN=TCP1 PE=1 SV=1 6.76 1490.8 - 823352 - - - -0.628 - 2.029 0.422 - 201.9 1 1 0 -0.0009 12 0 0 0 2.63E+06 7.08E+06 - - - 5.2058 0.9998 221125_WJC_METTL3_EV_vs_WT_F10.05121.05121.3 0.00049 14/48 K.TVAPMPPAQDHK[136.11]R[166.11].L "sp|P22102|PUR2_HUMAN,tr|F8WD69|F8WD69_HUMAN,tr|H7C366|H7C366_HUMAN,tr|C9JTV6|C9JTV6_HUMAN,tr|C9JBJ1|C9JBJ1_HUMAN" 5 1464.7626 1.55 138701 5121 3 1464.767084 489.2615 Trifunctional purine biosynthetic protein adenosine-3 OS=Homo sapiens OX=9606 GN=GART PE=1 SV=1 8.44 1491.2 - 481566 - - - 3.0353 - 2.594 0.421 - 245.4 1 2 0 0.0044 13 0 0 0 8.08E+06 5.20E+06 - - - 5.8169 0.9995 221125_WJC_METTL3_EV_vs_WT_F10.05123.05123.2 0.000384 18-Aug K.DSDLSHVQNK[136.11].S "sp|O60506|HNRPQ_HUMAN,tr|A0A7I2YQV8|A0A7I2YQV8_HUMAN,tr|A0A7I2YQN2|A0A7I2YQN2_HUMAN,tr|A0A7I2V5Q6|A0A7I2V5Q6_HUMAN,tr|A0A7I2V4Z0|A0A7I2V4Z0_HUMAN,tr|A0A7I2V4J0|A0A7I2V4J0_HUMAN,tr|F6UXX1|F6UXX1_HUMAN,tr|A0A7I2V346|A0A7I2V346_HUMAN" 8 1149.5506 0.87 138703 5123 2 1149.549758 575.7826 Heterogeneous nuclear ribonucleoprotein Q OS=Homo sapiens OX=9606 GN=SYNCRIP PE=1 SV=2 5.21 1491.5 - 423719 - - - -0.7029 - 1.491 0.392 - 128.4 1 2 0 -0.0008 10 0 0 0 1.84E+06 2.10E+06 - - - 3.051 0.9997 221125_WJC_METTL3_EV_vs_WT_F10.05124.05124.2 0.000766 22-Sep K.MIASDSHR[166.11]PEVK[136.11].L "sp|Q9NYF8|BCLF1_HUMAN,tr|E9PKI6|E9PKI6_HUMAN,tr|A0A1W2PQ43|A0A1W2PQ43_HUMAN,tr|E9PK91|E9PK91_HUMAN,tr|E9PJA7|E9PJA7_HUMAN,tr|E9PK09|E9PK09_HUMAN,tr|E9PQN2|E9PQN2_HUMAN" 7 1386.7045 2.5 138704 5124 2 1386.705845 694.3595 Bcl-2-associated transcription factor 1 OS=Homo sapiens OX=9606 GN=BCLAF1 PE=1 SV=2 6.51 1491.6 - 266249 - - - 1.0031 - 1.601 0.509 - 182 1 2 0 0.0014 12 0 0 0 4.65E+06 1.86E+06 - - - 4.0383 0.9988 221125_WJC_METTL3_EV_vs_WT_F10.05125.05125.2 0.000703 20-Sep R.SPHHALGLSSR.Y sp|Q96F45|ZN503_HUMAN 1 1160.6051 2.18 138705 5125 2 1160.608142 581.3098 Zinc finger protein 503 OS=Homo sapiens OX=9606 GN=ZNF503 PE=1 SV=1 9.51 1491.7 - 167500 - - - 2.6607 - 1.537 0.435 - 222.7 1 2 0 0.0031 11 0 0 0 7.91E+05 3.63E+05 - - - 3.4157 0.9999 221125_WJC_METTL3_EV_vs_WT_F10.05139.05139.3 2.48E-06 15/48 K.TVAPMPPAQDHKR.L "sp|P22102|PUR2_HUMAN,tr|F8WD69|F8WD69_HUMAN,tr|H7C366|H7C366_HUMAN,tr|C9JTV6|C9JTV6_HUMAN,tr|C9JBJ1|C9JBJ1_HUMAN" 5 1446.7402 1.35 138717 5139 3 1446.740701 483.254 Trifunctional purine biosynthetic protein adenosine-3 OS=Homo sapiens OX=9606 GN=GART PE=1 SV=1 8.44 1493.1 - 634679 - - - 0.3684 - 3.026 0.379 - 287 1 2 0 0.0005 13 0 0 0 8.07E+06 5.96E+06 - - - 5.7674 0.9866 221125_WJC_METTL3_EV_vs_WT_F10.05144.05144.2 1.24E-05 24-Aug K.NQQITHANNTVSN.F "sp|Q92598|HS105_HUMAN,tr|A0A0A0MSM0|A0A0A0MSM0_HUMAN,tr|R4GN69|R4GN69_HUMAN" 3 1439.6753 - 138722 5144 2 1439.675243 720.8449 Heat shock protein 105 kDa OS=Homo sapiens OX=9606 GN=HSPH1 PE=1 SV=1 6.74 1493.7 - 300284 - - - -0.0528 - 1.695 0.477 - 192.6 1 1 0 -0.0001 13 0 0 0 - - - - - 3.9184 0.9998 221125_WJC_METTL3_EV_vs_WT_F10.05145.05145.2 1.47E-05 26-Sep K.EANDSDVQPSGAQR[166.11].A "sp|O95707|RPP29_HUMAN,tr|K7ESH8|K7ESH8_HUMAN,tr|K7EQV2|K7EQV2_HUMAN,tr|K7ERD7|K7ERD7_HUMAN" 4 1482.6574 1.12 138723 5145 2 1482.659539 742.336 Ribonuclease P protein subunit p29 OS=Homo sapiens OX=9606 GN=POP4 PE=1 SV=2 4.03 1493.9 - 279791 - - - 1.4197 - 1.809 0.544 - 190.9 1 2 0 0.0021 14 0 0 0 1.15E+06 1.03E+06 - - - 4.5459 0.9991 221125_WJC_METTL3_EV_vs_WT_F10.05146.05146.2 0.00202 26-Apr K.EANDSDVQPSGAQR.A "sp|O95707|RPP29_HUMAN,tr|K7ESH8|K7ESH8_HUMAN,tr|K7EQV2|K7EQV2_HUMAN,tr|K7ERD7|K7ERD7_HUMAN" 4 1472.6492 1.12 138724 5146 2 1472.652968 737.3319 Ribonuclease P protein subunit p29 OS=Homo sapiens OX=9606 GN=POP4 PE=1 SV=2 4.03 1494 - 259565 - - - 2.5831 - 1.295 0.544 - 24.9 1 2 0 0.0038 14 0 0 0 1.15E+06 1.03E+06 - - - 3.7065 1 221125_WJC_METTL3_EV_vs_WT_F10.05147.05147.2 4.77E-08 14/30 V.SGLNSSASEPAK[136.11]EPAK[136.11].K "sp|Q86U44|MTA70_HUMAN,tr|F5H6D8|F5H6D8_HUMAN,tr|H0YFV6|H0YFV6_HUMAN,tr|B4DTN4|B4DTN4_HUMAN" 4 1587.8075 0.001 138725 5147 2 1587.808358 794.911 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 5.86 1494.1 - 240051 - - - 0.5309 - 2.868 0.613 - 652.7 1 1 1 0.0008 16 0 0 0 0.00E+00 1.95E+06 - - - 6.1587 0.9998 221125_WJC_METTL3_EV_vs_WT_F10.05153.05153.3 9.79E-05 Nov-44 K.LKGQADYEEVKK.E "sp|Q13948|CASP_HUMAN,sp|P39880|CUX1_HUMAN,tr|A0A2R8Y852|A0A2R8Y852_HUMAN,tr|A0A2R8YDI1|A0A2R8YDI1_HUMAN" 4 1406.7405 1.41 138730 5153 3 1406.740081 469.9208 Protein CASP OS=Homo sapiens OX=9606 GN=CUX1 PE=1 SV=2 6.18 1494.8 - 9.56E+06 - - - -0.3298 - 2.458 0.47 - 84.4 1 2 1 -0.0005 12 0 0 0 3.62E+07 2.57E+07 - - - 6.2728 0.9988 221125_WJC_METTL3_EV_vs_WT_F10.05158.05158.3 0.00143 13/48 K.VGGTSDVEVNEK[136.11]K[136.11].D "sp|P10809|CH60_HUMAN,tr|A0A7I2V2X6|A0A7I2V2X6_HUMAN,tr|A0A7I2YQK6|A0A7I2YQK6_HUMAN,tr|A0A7I2V599|A0A7I2V599_HUMAN" 4 1376.7118 1.07 138735 5158 3 1376.706933 459.9112 "60 kDa heat shock protein, mitochondrial OS=Homo sapiens OX=9606 GN=HSPD1 PE=1 SV=2" 4.68 1495 - 2.19E+06 - - - -3.5527 - 2.269 0.335 - 190 1 2 0 -0.0049 13 0 0 0 2.19E+07 2.06E+07 - - - 4.495 1 221125_WJC_METTL3_EV_vs_WT_F10.05162.05162.3 0.000115 15/48 K.VGGTSDVEVNEKK.D "sp|P10809|CH60_HUMAN,tr|A0A7I2V2X6|A0A7I2V2X6_HUMAN,tr|A0A7I2YQK6|A0A7I2YQK6_HUMAN,tr|A0A7I2V599|A0A7I2V599_HUMAN" 4 1360.6834 0.96 138739 5162 3 1360.683168 454.5684 "60 kDa heat shock protein, mitochondrial OS=Homo sapiens OX=9606 GN=HSPD1 PE=1 SV=2" 4.68 1495.2 - 1.57E+06 - - - -0.1881 - 2.802 0.502 - 401.1 1 2 0 -0.0003 13 0 0 0 2.86E+07 2.97E+07 - - - 6.9303 1 221125_WJC_METTL3_EV_vs_WT_F10.05173.05173.2 1.32E-08 13/26 K.SPPSTGSTYGSSQK.E "sp|Q9Y2W1|TR150_HUMAN,tr|A0A3B3ITZ9|A0A3B3ITZ9_HUMAN" 2 1382.6314 3.26 138749 5173 2 1382.630736 692.323 Thyroid hormone receptor-associated protein 3 OS=Homo sapiens OX=9606 GN=THRAP3 PE=1 SV=2 8.31 1496.5 - 1.35E+06 - - - -0.4716 - 2.603 0.644 - 321.7 1 2 0 -0.0007 14 0 0 0 1.69E+07 5.18E+06 - - - 6.1981 0.999 221125_WJC_METTL3_EV_vs_WT_F10.05177.05177.3 3.13E-07 13/40 V.IDC[160.03]HTAHIAC[160.03]K.F "sp|Q05639|EF1A2_HUMAN,sp|P68104|EF1A1_HUMAN,tr|A0A7I2V659|A0A7I2V659_HUMAN,tr|A0A2U3TZH3|A0A2U3TZH3_HUMAN,tr|A0A7I2V5N4|A0A7I2V5N4_HUMAN,tr|A0A087WVQ9|A0A087WVQ9_HUMAN,tr|A0A087WV01|A0A087WV01_HUMAN" 7 1324.6016 0.1 138753 5177 3 1324.601932 442.5412 Elongation factor 1-alpha 2 OS=Homo sapiens OX=9606 GN=EEF1A2 PE=1 SV=1 6.9 1496.6 - 1.46E+06 - - - 0.231 - 2.715 0.621 - 191.2 1 1 0 0.0003 11 0 0 0 6.72E+06 6.95E+07 - - - 8.3008 1 221125_WJC_METTL3_EV_vs_WT_F10.05183.05183.3 5.84E-05 17/48 K.KPAPPPAPPQATK.T "sp|Q86VM9|ZCH18_HUMAN,tr|H3BRN6|H3BRN6_HUMAN,tr|E7ERS3|E7ERS3_HUMAN" 3 1298.7347 1.46 138759 5183 3 1298.735728 433.9188 Zinc finger CCCH domain-containing protein 18 OS=Homo sapiens OX=9606 GN=ZC3H18 PE=1 SV=2 10 1497.2 - 706294 - - - 0.8131 - 2.845 0.44 - 435.3 1 2 0 0.0011 13 0 0 0 1.95E+07 1.34E+07 - - - 6.2801 0.9959 221125_WJC_METTL3_EV_vs_WT_F10.05185.05185.2 0.339 18-Aug R.K[136.11]QDSGHLDLR[166.11].N "sp|Q86U44|MTA70_HUMAN,tr|B4E349|B4E349_HUMAN,tr|F5H6D8|F5H6D8_HUMAN,tr|B4DTN4|B4DTN4_HUMAN" 4 1185.6221 0.02 138761 5185 2 1185.621514 593.8183 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 6.75 1497.4 - 471565 - - - -0.4985 - 1.213 0.228 - 176.4 1 2 0 -0.0006 10 0 0 0 5.42E+06 2.22E+08 - - - 1.2638 0.9997 221125_WJC_METTL3_EV_vs_WT_F10.05187.05187.2 6.19E-06 24-Oct K.VGGTSDVEVNEK[136.11]K[136.11].D "sp|P10809|CH60_HUMAN,tr|A0A7I2V2X6|A0A7I2V2X6_HUMAN,tr|A0A7I2YQK6|A0A7I2YQK6_HUMAN,tr|A0A7I2V599|A0A7I2V599_HUMAN" 4 1376.7118 -1 138763 5187 2 1376.708506 689.3632 "60 kDa heat shock protein, mitochondrial OS=Homo sapiens OX=9606 GN=HSPD1 PE=1 SV=2" 4.68 1497.7 - 374717 - - - -2.4101 - 2.205 0.519 - 265.1 1 2 0 -0.0033 13 0 0 0 0.00E+00 0.00E+00 - - - 4.9027 1 221125_WJC_METTL3_EV_vs_WT_F10.05190.05190.3 6.57E-09 18/60 K.TLGETSANAETEQNKK.K sp|Q5UIP0|RIF1_HUMAN 1 1719.8275 1.22 138766 5190 3 1719.828247 574.2831 Telomere-associated protein RIF1 OS=Homo sapiens OX=9606 GN=RIF1 PE=1 SV=2 4.78 1498.1 - 226739 - - - 0.4216 - 3.529 0.627 - 217.5 1 2 0 0.0007 16 0 0 0 1.79E+07 1.47E+07 - - - 8.7658 0.9984 221125_WJC_METTL3_EV_vs_WT_F10.05202.05202.3 0.397 Dec-32 R.K[136.11]EDIK[136.11]LEEK[136.11].K sp|Q9C0J8|WDR33_HUMAN 1 1154.6609 0.001 138776 5202 3 1154.65853 385.8942 pre-mRNA 3' end processing protein WDR33 OS=Homo sapiens OX=9606 GN=WDR33 PE=1 SV=2 4.87 1499 - 2.68E+06 - - - -2.056 - 2.363 0.312 - 220.2 1 2 1 -0.0024 9 0 0 0 0.00E+00 1.85E+07 - - - 4.6095 1 221125_WJC_METTL3_EV_vs_WT_F10.05203.05203.3 2.82E-06 18/60 K.TLGETSANAETEQNK[136.11]K[136.11].K sp|Q5UIP0|RIF1_HUMAN 1 1735.8559 1.22 138777 5203 3 1735.853113 579.6259 Telomere-associated protein RIF1 OS=Homo sapiens OX=9606 GN=RIF1 PE=1 SV=2 4.78 1499.1 - 2.38E+06 - - - -1.6182 - 3.495 0.612 - 200.1 1 2 0 -0.0028 16 0 0 0 1.79E+07 1.47E+07 - - - 8.5732 1 221125_WJC_METTL3_EV_vs_WT_F10.05205.05205.3 8.17E-06 14/56 K.EVAGAK[136.11]PHITAAEGK[136.11].L "sp|Q16891|MIC60_HUMAN,tr|B9A067|B9A067_HUMAN,tr|C9J406|C9J406_HUMAN,tr|H7C463|H7C463_HUMAN" 4 1493.8173 1.44 138779 5205 3 1493.814408 498.9464 MICOS complex subunit MIC60 OS=Homo sapiens OX=9606 GN=IMMT PE=1 SV=1 6.85 1499.3 - 991565 - - - -1.9306 - 2.866 0.523 - 167.6 1 2 0 -0.0029 15 0 0 0 4.05E+08 2.81E+08 - - - 7.1176 1 221125_WJC_METTL3_EV_vs_WT_F10.05207.05207.3 2.21E-07 20/56 K.EVAGAKPHITAAEGK.L "sp|Q16891|MIC60_HUMAN,tr|B9A067|B9A067_HUMAN,tr|C9J406|C9J406_HUMAN,tr|H7C463|H7C463_HUMAN" 4 1477.7889 1.44 138781 5207 3 1477.788901 493.6036 MICOS complex subunit MIC60 OS=Homo sapiens OX=9606 GN=IMMT PE=1 SV=1 6.85 1499.5 - 881315 - - - 0.0061 - 3.536 0.507 - 416.5 1 2 0 0 15 0 0 0 4.05E+08 2.81E+08 - - - 7.4882 0.9998 221125_WJC_METTL3_EV_vs_WT_F10.05210.05210.2 2.56E-06 30-Dec R.SATDGNTSTTPPTSAK[136.11].K "sp|Q13620|CUL4B_HUMAN,tr|A0A669KAX4|A0A669KAX4_HUMAN,tr|A0A7P0T8W4|A0A7P0T8W4_HUMAN,tr|K4DI93|K4DI93_HUMAN,tr|A0A804CL36|A0A804CL36_HUMAN,tr|A0A7P0T954|A0A7P0T954_HUMAN,tr|A0A669KAU9|A0A669KAU9_HUMAN,tr|A0A7P0T9R8|A0A7P0T9R8_HUMAN,tr|A0A7P0TAQ3|A0A7P0TAQ3_HUMAN" 9 1542.7253 0.95 138784 5210 2 1542.72352 772.3699 Cullin-4B OS=Homo sapiens OX=9606 GN=CUL4B PE=1 SV=4 5.55 1499.9 - 548199 - - - -1.1506 - 1.9 0.509 - 290 1 2 0 -0.0018 16 0 0 0 2.86E+06 3.00E+06 - - - 4.3779 0.9991 221125_WJC_METTL3_EV_vs_WT_F10.05215.05215.3 0.00027 Nov-40 K.EKEESMKETLR.L "sp|P0CG22|DR4L1_HUMAN,sp|Q9BTZ2|DHRS4_HUMAN,tr|H0YNP7|H0YNP7_HUMAN,tr|F5GWZ1|F5GWZ1_HUMAN,tr|E9PFL3|E9PFL3_HUMAN,tr|A0A087WXI8|A0A087WXI8_HUMAN" 6 1378.6762 1.67 138787 5215 3 1378.672948 460.566 Putative dehydrogenase\reductase SDR family member 4-like 1 OS=Homo sapiens OX=9606 GN=DHRS4L1 PE=5 SV=1 4.95 1500.4 - 4.57E+06 - - - -2.3805 - 2.179 0.418 - 147 1 2 2 -0.0033 11 0 0 0 3.28E+07 1.96E+07 - - - 5.412 1 221125_WJC_METTL3_EV_vs_WT_F10.05221.05221.2 2.75E-10 13/24 R.ATC[160.03]DC[160.03]PNC[160.03]QEAER.L "sp|Q8IXZ3|SP8_HUMAN,sp|P0CG40|SP9_HUMAN,tr|A0A087X0Q6|A0A087X0Q6_HUMAN" 3 1609.5919 1.93 138793 5221 2 1609.593508 805.8032 Transcription factor Sp8 OS=Homo sapiens OX=9606 GN=SP8 PE=1 SV=3 4.14 1500.9 - 1.02E+06 - - - 0.9829 - 2.827 0.788 - 495.4 1 2 0 0.0016 13 0 0 0 1.23E+07 6.37E+06 - - - 7.5278 1 221125_WJC_METTL3_EV_vs_WT_F10.05222.05222.2 4.11E-10 17/28 K.APTADTQTQNVNQAK.M sp|Q9Y5V3|MAGD1_HUMAN 1 1585.7696 1.65 138794 5222 2 1585.769625 793.8921 Melanoma-associated antigen D1 OS=Homo sapiens OX=9606 GN=MAGED1 PE=1 SV=3 5.88 1501 - 638970 - - - 0.0076 - 3.844 0.663 - 1150.3 1 2 0 0 15 0 0 0 9.39E+06 5.69E+06 - - - 7.2484 0.9988 221125_WJC_METTL3_EV_vs_WT_F10.05229.05229.3 0.00278 Dec-52 K.K[136.11]PASSSSAPQNIPK[136.11].R "sp|Q96F86|EDC3_HUMAN,tr|H3BPW9|H3BPW9_HUMAN,tr|H3BQ37|H3BQ37_HUMAN,tr|H3BQP5|H3BQP5_HUMAN,tr|H3BU87|H3BU87_HUMAN" 5 1426.7751 1.13 138799 5229 3 1426.7734 476.599 Enhancer of mRNA-decapping protein 3 OS=Homo sapiens OX=9606 GN=EDC3 PE=1 SV=1 10 1501.7 - 2.03E+06 - - - -1.1866 - 2.065 0.251 - 254 1 2 0 -0.0017 14 0 0 0 2.68E+07 2.37E+07 - - - 3.265 1 221125_WJC_METTL3_EV_vs_WT_F10.05231.05231.2 9.12E-06 20/28 K.EVAGAKPHITAAEGK.L "sp|Q16891|MIC60_HUMAN,tr|B9A067|B9A067_HUMAN,tr|C9J406|C9J406_HUMAN,tr|H7C463|H7C463_HUMAN" 4 1477.7889 1.48 138801 5231 2 1477.788645 739.9017 MICOS complex subunit MIC60 OS=Homo sapiens OX=9606 GN=IMMT PE=1 SV=1 6.85 1501.9 - 1.12E+06 - - - -0.1671 - 3.876 0.564 - 1089 1 2 0 -0.0002 15 0 0 0 1.50E+07 1.01E+07 - - - 6.5375 1 221125_WJC_METTL3_EV_vs_WT_F10.05232.05232.2 5.43E-10 21/28 K.EVAGAK[136.11]PHITAAEGK[136.11].L "sp|Q16891|MIC60_HUMAN,tr|B9A067|B9A067_HUMAN,tr|C9J406|C9J406_HUMAN,tr|H7C463|H7C463_HUMAN" 4 1493.8173 1.48 138802 5232 2 1493.815133 747.9159 MICOS complex subunit MIC60 OS=Homo sapiens OX=9606 GN=IMMT PE=1 SV=1 6.85 1502.1 - 1.03E+06 - - - -1.4453 - 3.586 0.628 - 1153.5 1 2 0 -0.0022 15 0 0 0 1.50E+07 1.01E+07 - - - 6.8184 1 221125_WJC_METTL3_EV_vs_WT_F10.05233.05233.2 1.92E-09 15/28 K.APTADTQTQNVNQAK[136.11].M sp|Q9Y5V3|MAGD1_HUMAN 1 1593.7838 1.65 138803 5233 2 1593.780309 797.8992 Melanoma-associated antigen D1 OS=Homo sapiens OX=9606 GN=MAGED1 PE=1 SV=3 5.88 1502.2 - 809993 - - - -2.1985 - 3.254 0.609 - 991.6 1 2 0 -0.0035 15 0 0 0 9.39E+06 5.69E+06 - - - 6.4388 1 221125_WJC_METTL3_EV_vs_WT_F10.05234.05234.3 2.38E-05 15/52 R.RPLPTQQQPQPSQK.L "sp|Q9P0U4|CXXC1_HUMAN,tr|K7EQZ1|K7EQZ1_HUMAN,tr|K7EQ21|K7EQ21_HUMAN,tr|K7EKZ6|K7EKZ6_HUMAN,tr|A0A669KB29|A0A669KB29_HUMAN" 5 1631.8744 1.53 138804 5234 3 1631.87315 544.9654 CXXC-type zinc finger protein 1 OS=Homo sapiens OX=9606 GN=CXXC1 PE=1 SV=2 11 1502.3 - 733138 - - - -0.7372 - 2.563 0.437 - 353.5 1 2 0 -0.0012 14 0 0 0 6.15E+06 4.01E+06 - - - 5.913 1 221125_WJC_METTL3_EV_vs_WT_F10.05235.05235.2 1.26E-07 17/24 V.AGAKPHITAAEGK.L "sp|Q16891|MIC60_HUMAN,tr|B9A067|B9A067_HUMAN,tr|C9J406|C9J406_HUMAN,tr|H7C463|H7C463_HUMAN" 4 1249.6779 1.57 138805 5235 2 1249.674632 625.8462 MICOS complex subunit MIC60 OS=Homo sapiens OX=9606 GN=IMMT PE=1 SV=1 8.64 1502.5 - 714461 - - - -2.6031 - 2.417 0.609 - 520.1 1 1 0 -0.0033 13 0 0 0 7.34E+06 4.67E+06 - - - 5.8031 1 221125_WJC_METTL3_EV_vs_WT_F10.05236.05236.2 2.12E-09 24-Nov R.ATC[160.03]DC[160.03]PNC[160.03]QEAER[166.11].L "sp|Q8IXZ3|SP8_HUMAN,sp|P0CG40|SP9_HUMAN,tr|A0A087X0Q6|A0A087X0Q6_HUMAN" 3 1619.6002 1.93 138806 5236 2 1619.594765 810.8074 Transcription factor Sp8 OS=Homo sapiens OX=9606 GN=SP8 PE=1 SV=3 4.14 1502.6 - 597576 - - - -3.3533 - 2.577 0.726 - 358.4 1 2 0 -0.0054 13 0 0 0 1.23E+07 6.37E+06 - - - 6.8311 1 221125_WJC_METTL3_EV_vs_WT_F10.05237.05237.2 9.58E-06 18/24 V.AGAK[136.11]PHITAAEGK[136.11].L "sp|Q16891|MIC60_HUMAN,tr|B9A067|B9A067_HUMAN,tr|C9J406|C9J406_HUMAN,tr|H7C463|H7C463_HUMAN" 4 1265.7063 1.57 138807 5237 2 1265.703504 633.8604 MICOS complex subunit MIC60 OS=Homo sapiens OX=9606 GN=IMMT PE=1 SV=1 8.64 1502.7 - 446882 - - - -2.1972 - 2.975 0.56 - 555.2 1 1 0 -0.0028 13 0 0 0 7.34E+06 4.67E+06 - - - 5.9744 1 221125_WJC_METTL3_EV_vs_WT_F10.05240.05240.3 4.73E-06 19/48 R.RVPQAKPVAVEEK.V "sp|Q8WUD4|CCD12_HUMAN,tr|C9JUN5|C9JUN5_HUMAN,tr|J3KR35|J3KR35_HUMAN" 3 1449.8304 1.52 138808 5240 3 1449.827898 484.2841 Coiled-coil domain-containing protein 12 OS=Homo sapiens OX=9606 GN=CCDC12 PE=1 SV=1 8.59 1503.1 - 3.11E+06 - - - -1.7002 - 2.826 0.494 - 381.2 1 2 0 -0.0025 13 0 0 0 1.75E+07 1.15E+07 - - - 6.8636 0.9979 221125_WJC_METTL3_EV_vs_WT_F10.05245.05245.3 0.159 15/48 K.K[136.11]PAPPPAPPQATK[136.11].T "sp|Q86VM9|ZCH18_HUMAN,tr|H3BRN6|H3BRN6_HUMAN,tr|E7ERS3|E7ERS3_HUMAN" 3 1314.7631 1.46 138813 5245 3 1314.761137 439.2616 Zinc finger CCCH domain-containing protein 18 OS=Homo sapiens OX=9606 GN=ZC3H18 PE=1 SV=2 10 1503.6 - 1.01E+06 - - - -1.4717 - 2.164 0.208 - 315.8 1 2 0 -0.0019 13 0 0 0 1.95E+07 1.34E+07 - - - 2.9515 0.9995 221125_WJC_METTL3_EV_vs_WT_F10.05246.05246.2 0.00277 18-Oct K.VSRPENEQLR.N "sp|Q8ND56|LS14A_HUMAN,tr|A0A140TA76|A0A140TA76_HUMAN,tr|K7EMZ9|K7EMZ9_HUMAN" 3 1226.6367 1.27 138814 5246 2 1226.636135 614.3257 Protein LSM14 homolog A OS=Homo sapiens OX=9606 GN=LSM14A PE=1 SV=3 6.11 1503.7 - 740643 - - - -0.4997 - 1.58 0.374 - 95.2 1 2 0 -0.0006 10 0 0 0 3.66E+06 2.88E+06 - - - 3.08 0.9993 221125_WJC_METTL3_EV_vs_WT_F10.05250.05250.3 0.00704 Oct-52 K.KPASSSSAPQNIPK.R "sp|Q96F86|EDC3_HUMAN,tr|H3BPW9|H3BPW9_HUMAN,tr|H3BQ37|H3BQ37_HUMAN,tr|H3BQP5|H3BQP5_HUMAN,tr|H3BU87|H3BU87_HUMAN" 5 1410.7467 1.24 138816 5250 3 1410.743313 471.2562 Enhancer of mRNA-decapping protein 3 OS=Homo sapiens OX=9606 GN=EDC3 PE=1 SV=1 10 1504.2 - 3.79E+06 - - - -2.3959 - 1.976 0.353 - 147.2 1 2 0 -0.0034 14 0 0 0 2.60E+07 2.09E+07 - - - 4.2846 0.9999 221125_WJC_METTL3_EV_vs_WT_F10.05254.05254.3 9.88E-05 Oct-36 K.GHEFYNPQK[136.11]K[136.11].N sp|P78406|RAE1L_HUMAN 1 1262.6379 2.24 138820 5254 3 1262.637387 421.8866 mRNA export factor OS=Homo sapiens OX=9606 GN=RAE1 PE=1 SV=1 8.51 1504.5 - 1.41E+06 - - - -0.3833 - 2.12 0.438 - 178.4 1 2 0 -0.0005 10 0 0 0 3.83E+07 1.71E+07 - - - 5.6176 0.9999 221125_WJC_METTL3_EV_vs_WT_F10.05256.05256.3 2.57E-05 Dec-44 K.VLGQPHHELDSK[136.11].T "sp|Q96DH6|MSI2H_HUMAN,tr|B4DHE8|B4DHE8_HUMAN,tr|A0A6Q8PF05|A0A6Q8PF05_HUMAN,tr|J3QKT5|J3QKT5_HUMAN,tr|A0A6Q8PFU8|A0A6Q8PFU8_HUMAN,tr|J3KTC1|J3KTC1_HUMAN,tr|A0A6Q8PHT3|A0A6Q8PHT3_HUMAN" 7 1366.7085 2.11 138822 5256 3 1366.709753 456.5768 RNA-binding protein Musashi homolog 2 OS=Homo sapiens OX=9606 GN=MSI2 PE=1 SV=1 5.99 1504.6 - 1.23E+06 - - - 0.9439 - 2.354 0.418 - 194.8 1 2 0 0.0013 12 0 0 0 1.53E+07 7.25E+06 - - - 5.573 1 221125_WJC_METTL3_EV_vs_WT_F10.05263.05263.3 0.00159 21/56 K.QHPVPPPAQNQNQVR.S "sp|Q15942|ZYX_HUMAN,tr|H0Y2Y8|H0Y2Y8_HUMAN" 2 1708.8757 8.35 138828 5263 3 1708.87567 570.6325 Zyxin OS=Homo sapiens OX=9606 GN=ZYX PE=1 SV=1 9.76 1505.5 - 5.37E+06 - - - -0.0468 - 3.85 0.5 - 944.1 1 2 0 -0.0001 15 0 0 0 2.12E+08 2.54E+07 - - - 7.6321 0.9996 221125_WJC_METTL3_EV_vs_WT_F10.05269.05269.3 0.0273 Oct-36 K.THHNDTELIR.K sp|P49915|GUAA_HUMAN 1 1234.6054 0.92 138833 5269 3 1234.604986 412.5424 GMP synthase [glutamine-hydrolyzing] OS=Homo sapiens OX=9606 GN=GMPS PE=1 SV=1 5.92 1505.8 - 2.23E+06 - - - -0.3742 - 1.553 0.376 - 125.7 1 2 0 -0.0005 10 0 0 0 3.72E+07 4.05E+07 - - - 4.0174 1 221125_WJC_METTL3_EV_vs_WT_F10.05272.05272.3 7.12E-07 15/48 K.EEIQETQTPTHSR[166.11].K "sp|Q9BYG3|MK67I_HUMAN,tr|H7BZL0|H7BZL0_HUMAN" 2 1564.7357 2.39 138836 5272 3 1564.733745 522.5858 MKI67 FHA domain-interacting nucleolar phosphoprotein OS=Homo sapiens OX=9606 GN=NIFK PE=1 SV=1 4.75 1506.1 - 1.08E+06 - - - -1.2392 - 2.92 0.487 - 294.1 1 2 0 -0.0019 13 0 0 0 3.80E+07 1.59E+07 - - - 6.8744 1 221125_WJC_METTL3_EV_vs_WT_F10.05273.05273.2 5.75E-06 16/22 K.HVVQSISTQQEK.E "sp|P24539|AT5F1_HUMAN,tr|Q5QNZ2|Q5QNZ2_HUMAN" 2 1382.7154 1.15 138837 5273 2 1382.71507 692.365 "ATP synthase F(0) complex subunit B1, mitochondrial OS=Homo sapiens OX=9606 GN=ATP5PB PE=1 SV=2" 6.75 1506.2 - 1.00E+06 - - - -0.2336 - 2.824 0.625 - 770.8 1 2 0 -0.0003 12 0 0 0 4.69E+06 4.06E+06 - - - 6.3887 1 221125_WJC_METTL3_EV_vs_WT_F10.05274.05274.2 9.20E-07 15/22 K.HVVQSISTQQEK[136.11].E "sp|P24539|AT5F1_HUMAN,tr|Q5QNZ2|Q5QNZ2_HUMAN" 2 1390.7296 1.15 138838 5274 2 1390.728174 696.3721 "ATP synthase F(0) complex subunit B1, mitochondrial OS=Homo sapiens OX=9606 GN=ATP5PB PE=1 SV=2" 6.75 1506.3 - 736813 - - - -1.0203 - 2.797 0.602 - 591.9 1 2 0 -0.0014 12 0 0 0 4.69E+06 4.06E+06 - - - 6.1932 0.8714 221125_WJC_METTL3_EV_vs_WT_F10.05275.05275.2 58.8 24-Feb R.C[160.03]PQHC[160.03]C[160.03]SAC[160.03]SMEK.D sp|Q9BZ95|NSD3_HUMAN 1 1653.5826 999 138839 5275 2 1653.580038 827.7986 Histone-lysine N-methyltransferase NSD3 OS=Homo sapiens OX=9606 GN=NSD3 PE=1 SV=1 6.71 1506.4 - 464753 - - - -1.5639 - 0.477 0.282 - 6.7 1 2 0 -0.0026 13 0 0 0 3.48E+06 0.00E+00 - - - -0.7768 1 221125_WJC_METTL3_EV_vs_WT_F10.05279.05279.2 3.21E-11 18/36 K.TLASSSSSSSSSSGAETPK.Q "sp|Q9Y467|SALL2_HUMAN,tr|F5H433|F5H433_HUMAN" 2 1756.7963 1.91 138843 5279 2 1756.796271 879.4054 Sal-like protein 2 OS=Homo sapiens OX=9606 GN=SALL2 PE=1 SV=4 5.66 1506.9 - 339216 - - - -0.0057 - 4.273 0.733 - 877.7 1 2 0 0 19 0 0 0 1.25E+07 6.53E+06 - - - 8.0255 1 221125_WJC_METTL3_EV_vs_WT_F10.05282.05282.2 2.17E-10 18/36 K.TLASSSSSSSSSSGAETPK[136.11].Q "sp|Q9Y467|SALL2_HUMAN,tr|F5H433|F5H433_HUMAN" 2 1764.8105 1.91 138846 5282 2 1764.807701 883.4125 Sal-like protein 2 OS=Homo sapiens OX=9606 GN=SALL2 PE=1 SV=4 5.66 1507.3 - 319350 - - - -1.5752 - 4.112 0.728 - 778.5 1 2 0 -0.0028 19 0 0 0 1.25E+07 6.53E+06 - - - 7.8933 1 221125_WJC_METTL3_EV_vs_WT_F10.05290.05290.3 2.50E-05 20/48 K.EEIQETQTPTHSR.K "sp|Q9BYG3|MK67I_HUMAN,tr|H7BZL0|H7BZL0_HUMAN" 2 1554.7274 2.42 138853 5290 3 1554.728874 519.2497 MKI67 FHA domain-interacting nucleolar phosphoprotein OS=Homo sapiens OX=9606 GN=NIFK PE=1 SV=1 4.75 1508.1 - 4.96E+06 - - - 0.9391 - 3.567 0.433 - 557.4 1 2 0 0.0015 13 0 0 0 3.86E+07 1.59E+07 - - - 6.8151 0.9762 221125_WJC_METTL3_EV_vs_WT_F10.05293.05293.2 0.518 12-Sep D.SGHLDLR[166.11].N "sp|Q86U44|MTA70_HUMAN,tr|D6R9M9|D6R9M9_HUMAN,tr|B4E349|B4E349_HUMAN,tr|F5H6D8|F5H6D8_HUMAN,tr|B4DTN4|B4DTN4_HUMAN,tr|D6R9X6|D6R9X6_HUMAN" 6 806.4274 0.03 138856 5293 2 806.427238 404.221 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 6.46 1508.2 - 2.53E+06 - - - -0.2269 - 1.65 0.353 - 381.1 1 1 0 -0.0002 7 0 0 0 7.51E+08 2.30E+10 - - - 3.2349 0.9997 221125_WJC_METTL3_EV_vs_WT_F10.05296.05296.2 0.147 18-Dec R.RQVDQLTNDK.A "sp|P08670|VIME_HUMAN,tr|B0YJC4|B0YJC4_HUMAN" 2 1215.6208 -1 138859 5296 2 1215.621281 608.8177 Vimentin OS=Homo sapiens OX=9606 GN=VIM PE=1 SV=4 5.96 1508.5 - 986061 - - - 0.4253 - 2.541 0.258 - 532.1 1 2 0 0.0005 10 0 0 0 0.00E+00 0.00E+00 - - - 3.5495 1 221125_WJC_METTL3_EV_vs_WT_F10.05298.05298.3 1.91E-13 24/56 R.VLHNAQEVEKEPGQR.R "sp|P49916|DNLI3_HUMAN,tr|K7ERZ5|K7ERZ5_HUMAN" 2 1732.8856 -1 138861 5298 3 1732.890545 578.6358 DNA ligase 3 OS=Homo sapiens OX=9606 GN=LIG3 PE=1 SV=2 5.5 1508.7 - 596645 - - - 2.8271 - 3.965 0.582 - 651.7 1 2 1 0.0049 15 0 0 0 0.00E+00 0.00E+00 - - - 8.6218 0.9998 221125_WJC_METTL3_EV_vs_WT_F10.05301.05301.3 5.27E-06 15/56 R.VLHNAQEVEK[136.11]EPGQR[166.11].R "sp|P49916|DNLI3_HUMAN,tr|K7ERZ5|K7ERZ5_HUMAN" 2 1750.9081 -1 138864 5301 3 1750.911157 584.6433 DNA ligase 3 OS=Homo sapiens OX=9606 GN=LIG3 PE=1 SV=2 5.5 1509.1 - 488993 - - - 1.7368 - 2.623 0.527 - 193.8 1 2 1 0.003 15 0 0 0 0.00E+00 0.00E+00 - - - 6.9309 0.9997 221125_WJC_METTL3_EV_vs_WT_F10.05302.05302.2 0.000709 13/18 R.R[166.11]QVDQLTNDK[136.11].A "sp|P08670|VIME_HUMAN,tr|B0YJC4|B0YJC4_HUMAN" 2 1233.6432 -1 138865 5302 2 1233.641524 617.8289 Vimentin OS=Homo sapiens OX=9606 GN=VIM PE=1 SV=4 5.96 1509.3 - 477805 - - - -1.3861 - 2.594 0.321 - 711.6 1 2 0 -0.0017 10 0 0 0 0.00E+00 0.00E+00 - - - 4.072 1 221125_WJC_METTL3_EV_vs_WT_F10.05304.05304.2 3.32E-09 Nov-34 K.QIAESANSSSPQSSAGGK.P "sp|P42694|HELZ_HUMAN,tr|J3QS41|J3QS41_HUMAN" 2 1704.7915 -1 138867 5304 2 1704.792133 853.403 Probable helicase with zinc finger domain OS=Homo sapiens OX=9606 GN=HELZ PE=1 SV=2 6 1509.5 - 424491 - - - 0.3883 - 2.625 0.667 - 243.5 1 1 0 0.0007 18 0 0 0 0.00E+00 0.00E+00 - - - 6.3399 0.8334 221125_WJC_METTL3_EV_vs_WT_F10.05309.05309.2 2.84 14-Aug Q.DSGHLDLR[166.11].N "sp|Q86U44|MTA70_HUMAN,tr|B4E349|B4E349_HUMAN,tr|F5H6D8|F5H6D8_HUMAN,tr|B4DTN4|B4DTN4_HUMAN" 4 921.4544 0.02 138871 5309 2 921.452193 461.7345 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 5.21 1510 - 6.22E+07 - - - -2.3561 - 1.943 0.159 - 247.3 1 1 0 -0.0022 8 0 0 0 2.41E+08 1.27E+10 - - - 2.218 0.9998 221125_WJC_METTL3_EV_vs_WT_F10.05316.05316.3 0.00036 13/40 K.QRPQATAEQIR.L "sp|Q14157|UBP2L_HUMAN,tr|Q5VU78|Q5VU78_HUMAN,tr|F8W726|F8W726_HUMAN,tr|Q5VU81|Q5VU81_HUMAN,tr|Q5VU79|Q5VU79_HUMAN,tr|Q5VU80|Q5VU80_HUMAN,tr|Q5VU77|Q5VU77_HUMAN" 7 1296.6898 -1 138878 5316 3 1296.687587 433.2372 Ubiquitin-associated protein 2-like OS=Homo sapiens OX=9606 GN=UBAP2L PE=1 SV=2 9.6 1510.3 - 3.28E+06 - - - -1.7429 - 1.941 0.403 - 204.5 1 2 0 -0.0023 11 0 0 0 0.00E+00 0.00E+00 - - - 4.9165 0.9999 221125_WJC_METTL3_EV_vs_WT_F10.05333.05333.2 5.89E-05 14/18 R.KQDSGHLDLR.N "sp|Q86U44|MTA70_HUMAN,tr|B4E349|B4E349_HUMAN,tr|F5H6D8|F5H6D8_HUMAN,tr|B4DTN4|B4DTN4_HUMAN" 4 1167.5996 0 138891 5333 2 1167.598864 584.8071 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 6.75 1511.9 - 4.22E+06 - - - -0.6603 - 2.668 0.523 - 627.7 1 2 0 -0.0008 10 0 0 0 2.59E+08 6.18E+10 - - - 5.6428 0.9773 221125_WJC_METTL3_EV_vs_WT_F10.05341.05341.2 0.116 14-Oct Q.DSGHLDLR.N "sp|Q86U44|MTA70_HUMAN,tr|B4E349|B4E349_HUMAN,tr|F5H6D8|F5H6D8_HUMAN,tr|B4DTN4|B4DTN4_HUMAN" 4 911.4461 0.02 138894 5341 2 911.446631 456.7303 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 5.21 1512.9 - 8.31E+06 - - - 0.5892 - 2.149 0.28 - 384.1 1 1 0 0.0005 8 0 0 0 2.41E+08 1.27E+10 - - - 3.4161 0.9173 221125_WJC_METTL3_EV_vs_WT_F10.05350.05350.2 5.51 12-May K.C[160.03]TAVEIR[166.11].N sp|Q8TDY2|RBCC1_HUMAN 1 857.4305 0 138896 5350 2 857.432887 429.7225 RB1-inducible coiled-coil protein 1 OS=Homo sapiens OX=9606 GN=RB1CC1 PE=1 SV=3 5.99 1514.2 - 1.24E+07 - - - 2.8329 - 1.179 0.092 - 116.5 2 2 0 0.0024 7 0 0 0 1.39E+05 5.12E+08 - - - 0.107 1 221125_WJC_METTL3_EV_vs_WT_F10.05365.05365.3 1.40E-06 15/36 R.K[136.11]QDSGHLDLR[166.11].N "sp|Q86U44|MTA70_HUMAN,tr|B4E349|B4E349_HUMAN,tr|F5H6D8|F5H6D8_HUMAN,tr|B4DTN4|B4DTN4_HUMAN" 4 1185.6221 0.02 138898 5365 3 1185.621198 396.2146 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 6.75 1516.6 - 6.38E+09 - - - -0.765 - 2.771 0.581 - 272.7 1 2 0 -0.0009 10 0 0 0 7.13E+09 2.99E+11 - - - 7.9939 0.9993 221125_WJC_METTL3_EV_vs_WT_F10.05371.05371.3 3.17E-06 16/44 R.FK[136.11]ETNDK[136.11]AELDR[166.11].Q sp|Q13123|RED_HUMAN 1 1490.7575 1.71 138899 5371 3 1490.7531 497.9265 Protein Red OS=Homo sapiens OX=9606 GN=IK PE=1 SV=3 4.78 1517.4 - 4.29E+06 - - - -2.9797 - 2.785 0.427 - 272.2 1 2 2 -0.0044 12 0 0 0 1.05E+08 6.13E+07 - - - 6.1385 0.9987 221125_WJC_METTL3_EV_vs_WT_F10.05375.05375.3 1.37E-05 15/44 R.FKETNDKAELDR.Q sp|Q13123|RED_HUMAN 1 1464.7209 1.71 138900 5375 3 1464.717124 489.2476 Protein Red OS=Homo sapiens OX=9606 GN=IK PE=1 SV=3 4.78 1518 - 6.47E+06 - - - -2.5588 - 2.588 0.354 - 248.3 1 2 2 -0.0037 12 0 0 0 1.05E+08 6.13E+07 - - - 5.1214 0.9919 221125_WJC_METTL3_EV_vs_WT_F10.05377.05377.3 0.0052 13/48 R.EDSQRPGAHLTVK.K "sp|Q32P51|RA1L2_HUMAN,sp|P09651|ROA1_HUMAN,tr|A0A7I2YQX9|A0A7I2YQX9_HUMAN,tr|F8W646|F8W646_HUMAN,tr|F8VZ49|F8VZ49_HUMAN,tr|A0A7I2V3R8|A0A7I2V3R8_HUMAN,tr|F8W6I7|F8W6I7_HUMAN,tr|A0A7I2V2L6|A0A7I2V2L6_HUMAN,tr|A0A7I2V3W0|A0A7I2V3W0_HUMAN,tr|A0A7I2V5U9|A0A7I2V5U9_HUMAN" 10 1436.7372 1.29 138901 5377 3 1436.731934 479.9197 Heterogeneous nuclear ribonucleoprotein A1-like 2 OS=Homo sapiens OX=9606 GN=HNRNPA1L2 PE=2 SV=2 6.85 1518.2 - 6.26E+06 - - - -3.659 - 1.588 0.297 - 57.7 1 2 0 -0.0053 13 0 0 0 1.83E+09 1.42E+09 - - - 3.1037 0.9998 221125_WJC_METTL3_EV_vs_WT_F10.05380.05380.3 1.64E-06 15/48 R.EDSQR[166.11]PGAHLTVK[136.11].K "sp|Q32P51|RA1L2_HUMAN,sp|P09651|ROA1_HUMAN,tr|A0A7I2YQX9|A0A7I2YQX9_HUMAN,tr|F8W646|F8W646_HUMAN,tr|F8VZ49|F8VZ49_HUMAN,tr|A0A7I2V3R8|A0A7I2V3R8_HUMAN,tr|F8W6I7|F8W6I7_HUMAN,tr|A0A7I2V2L6|A0A7I2V2L6_HUMAN,tr|A0A7I2V3W0|A0A7I2V3W0_HUMAN,tr|A0A7I2V5U9|A0A7I2V5U9_HUMAN" 10 1454.7597 1.29 138902 5380 3 1454.753782 485.9272 Heterogeneous nuclear ribonucleoprotein A1-like 2 OS=Homo sapiens OX=9606 GN=HNRNPA1L2 PE=2 SV=2 6.85 1518.6 - 1.33E+07 - - - -4.0412 - 2.601 0.509 - 294.9 1 2 0 -0.0059 13 0 0 0 1.83E+09 1.42E+09 - - - 6.8049 0.9976 221125_WJC_METTL3_EV_vs_WT_F10.05381.05381.3 0.000861 13/44 R.K[136.11]YELGR[166.11]PAANTK[136.11].L "sp|P62241|RS8_HUMAN,tr|Q5JR95|Q5JR95_HUMAN" 2 1372.7673 0.89 138903 5381 3 1372.762149 458.5964 40S ribosomal protein S8 OS=Homo sapiens OX=9606 GN=RPS8 PE=1 SV=2 9.7 1518.7 - 6.85E+06 - - - -3.7661 - 2.264 0.292 - 187.6 1 2 0 -0.0052 12 0 0 0 7.37E+07 8.29E+07 - - - 4.0591 0.999 221125_WJC_METTL3_EV_vs_WT_F10.05382.05382.3 0.0102 Dec-44 R.KYELGRPAANTK.L "sp|P62241|RS8_HUMAN,tr|Q5JR95|Q5JR95_HUMAN" 2 1346.7306 0.89 138904 5382 3 1346.725559 449.9175 40S ribosomal protein S8 OS=Homo sapiens OX=9606 GN=RPS8 PE=1 SV=2 9.7 1518.7 - 5.01E+06 - - - -3.7795 - 2.413 0.342 - 174 1 2 0 -0.0051 12 0 0 0 7.37E+07 8.29E+07 - - - 4.7932 0.9994 221125_WJC_METTL3_EV_vs_WT_F10.05391.05391.2 0.00136 13/24 R.EDSQR[166.11]PGAHLTVK[136.11].K "sp|Q32P51|RA1L2_HUMAN,sp|P09651|ROA1_HUMAN,tr|A0A7I2YQX9|A0A7I2YQX9_HUMAN,tr|F8W646|F8W646_HUMAN,tr|F8VZ49|F8VZ49_HUMAN,tr|A0A7I2V3R8|A0A7I2V3R8_HUMAN,tr|F8W6I7|F8W6I7_HUMAN,tr|A0A7I2V2L6|A0A7I2V2L6_HUMAN,tr|A0A7I2V3W0|A0A7I2V3W0_HUMAN,tr|A0A7I2V5U9|A0A7I2V5U9_HUMAN" 10 1454.7597 1.18 138909 5391 2 1454.758826 728.3871 Heterogeneous nuclear ribonucleoprotein A1-like 2 OS=Homo sapiens OX=9606 GN=HNRNPA1L2 PE=2 SV=2 6.85 1519.9 - 2.39E+06 - - - -0.574 - 2.235 0.238 - 322.4 1 2 0 -0.0008 13 0 0 0 7.57E+07 6.39E+07 - - - 2.8627 0.9303 221125_WJC_METTL3_EV_vs_WT_F10.05397.05397.3 0.204 14/44 E.DSQRPGAHLTVK.K "sp|Q32P51|RA1L2_HUMAN,sp|P09651|ROA1_HUMAN,tr|A0A7I2YQX9|A0A7I2YQX9_HUMAN,tr|F8W646|F8W646_HUMAN,tr|F8VZ49|F8VZ49_HUMAN,tr|A0A7I2V3R8|A0A7I2V3R8_HUMAN,tr|F8VTQ5|F8VTQ5_HUMAN,tr|F8W6I7|F8W6I7_HUMAN,tr|A0A7I2V2L6|A0A7I2V2L6_HUMAN,tr|A0A7I2V3W0|A0A7I2V3W0_HUMAN,tr|A0A7I2V5U9|A0A7I2V5U9_HUMAN" 11 1307.6946 1.29 138913 5397 3 1307.690888 436.9055 Heterogeneous nuclear ribonucleoprotein A1-like 2 OS=Homo sapiens OX=9606 GN=HNRNPA1L2 PE=2 SV=2 8.75 1520.6 - 7.75E+06 - - - -2.8371 - 2.3 0.328 - 187.4 1 1 0 -0.0037 12 0 0 0 1.21E+08 9.38E+07 - - - 4.5045 1 221125_WJC_METTL3_EV_vs_WT_F10.05398.05398.2 3.86E-09 16/28 R.TTDGSLQNTSSEGSR.L "tr|A8MQB8|A8MQB8_HUMAN,tr|G3V0J0|G3V0J0_HUMAN" 2 1538.6809 1.58 138914 5398 2 1538.678513 770.3477 Synaptic functional regulator FMR1 OS=Homo sapiens OX=9606 GN=FMR1 PE=1 SV=1 4.37 1520.6 - 5.89E+06 - - - -1.524 - 3.326 0.661 - 900.5 1 2 0 -0.0023 15 0 0 0 1.37E+08 8.70E+07 - - - 6.877 0.9996 221125_WJC_METTL3_EV_vs_WT_F10.05399.05399.2 0.0186 24-Dec R.EDSQRPGAHLTVK.K "sp|Q32P51|RA1L2_HUMAN,sp|P09651|ROA1_HUMAN,tr|A0A7I2YQX9|A0A7I2YQX9_HUMAN,tr|F8W646|F8W646_HUMAN,tr|F8VZ49|F8VZ49_HUMAN,tr|A0A7I2V3R8|A0A7I2V3R8_HUMAN,tr|F8W6I7|F8W6I7_HUMAN,tr|A0A7I2V2L6|A0A7I2V2L6_HUMAN,tr|A0A7I2V3W0|A0A7I2V3W0_HUMAN,tr|A0A7I2V5U9|A0A7I2V5U9_HUMAN" 10 1436.7372 1.18 138915 5399 2 1436.7349 719.3759 Heterogeneous nuclear ribonucleoprotein A1-like 2 OS=Homo sapiens OX=9606 GN=HNRNPA1L2 PE=2 SV=2 6.85 1520.7 - 4.34E+06 - - - -1.5946 - 2.429 0.337 - 255.6 1 2 0 -0.0023 13 0 0 0 7.57E+07 6.39E+07 - - - 3.8071 0.9477 221125_WJC_METTL3_EV_vs_WT_F10.05402.05402.3 0.255 Nov-40 K.NIQFAHANKPK.G "sp|Q14241|ELOA1_HUMAN,tr|A0A024RAC6|A0A024RAC6_HUMAN" 2 1266.6833 0.41 138918 5402 3 1266.681353 423.235 Elongin-A OS=Homo sapiens OX=9606 GN=ELOA PE=1 SV=2 10 1520.8 - 3.49E+06 - - - -1.541 - 1.491 0.118 - 97.4 1 2 0 -0.002 11 0 0 0 5.62E+07 1.36E+08 - - - 0.9898 0.9999 221125_WJC_METTL3_EV_vs_WT_F10.05407.05407.3 0.000168 14/44 R.R[166.11]MEELHNQEMQK[136.11].R "sp|P23246|SFPQ_HUMAN,tr|H0Y9K7|H0Y9K7_HUMAN" 2 1589.7409 0.71 138921 5407 3 1589.737861 530.9209 "Splicing factor, proline- and glutamine-rich OS=Homo sapiens OX=9606 GN=SFPQ PE=1 SV=2" 5.5 1521.4 - 4.06E+06 - - - -1.9217 - 2.659 0.44 - 237.6 1 2 0 -0.0031 12 0 0 0 6.24E+07 8.79E+07 - - - 6.1555 1 221125_WJC_METTL3_EV_vs_WT_F10.05408.05408.2 7.07E-05 16/32 R.GGSGGSHGGGSGFGGES.G "sp|P35527|K1C9_HUMAN,tr|K7EQQ3|K7EQQ3_HUMAN" 2 1349.5232 - 138922 5408 2 1349.521651 675.7689 "Keratin, type I cytoskeletal 9 OS=Homo sapiens OX=9606 GN=KRT9 PE=1 SV=3" 5.24 1521.5 - 1.40E+06 - - - -1.1737 - 3.276 0.651 - 783.6 1 1 0 -0.0016 17 0 0 0 - - - - - 6.7662 1 221125_WJC_METTL3_EV_vs_WT_F10.05409.05409.2 6.81E-05 16/26 R.QSSGASSSSFSSSR.A "sp|O00571|DDX3X_HUMAN,tr|A0A2R8YFR4|A0A2R8YFR4_HUMAN,tr|A0A2R8YCW1|A0A2R8YCW1_HUMAN,tr|A0A2R8YDT5|A0A2R8YDT5_HUMAN,tr|A0A2R8Y645|A0A2R8Y645_HUMAN,tr|A0A2R8YF78|A0A2R8YF78_HUMAN,tr|A0A0D9SFB3|A0A0D9SFB3_HUMAN,tr|A0A2R8YFS5|A0A2R8YFS5_HUMAN,tr|A0A0D9SF53|A0A0D9SF53_HUMAN,tr|A0A087WVZ1|A0A087WVZ1_HUMAN,tr|A0A0J9YVQ7|A0A0J9YVQ7_HUMAN,tr|A0A2R8Y5G6|A0A2R8Y5G6_HUMAN,tr|A0A2R8Y7T2|A0A2R8Y7T2_HUMAN,tr|A0A0D9SG12|A0A0D9SG12_HUMAN,tr|F6S8Q4|F6S8Q4_HUMAN,tr|A0A2U3TZJ9|A0A2U3TZJ9_HUMAN,tr|A0A2R8Y4A4|A0A2R8Y4A4_HUMAN" 17 1360.5855 1.13 138923 5409 2 1360.583329 681.3 ATP-dependent RNA helicase DDX3X OS=Homo sapiens OX=9606 GN=DDX3X PE=1 SV=3 9.75 1521.6 - 2.04E+06 - - - -1.5964 - 2.88 0.577 - 878.1 1 2 0 -0.0022 14 0 0 0 2.50E+08 2.21E+08 - - - 5.9565 1 221125_WJC_METTL3_EV_vs_WT_F10.05410.05410.2 7.94E-08 17/26 R.QSSGASSSSFSSSR[166.11].A "sp|O00571|DDX3X_HUMAN,tr|A0A2R8YFR4|A0A2R8YFR4_HUMAN,tr|A0A2R8YCW1|A0A2R8YCW1_HUMAN,tr|A0A2R8YDT5|A0A2R8YDT5_HUMAN,tr|A0A2R8Y645|A0A2R8Y645_HUMAN,tr|A0A2R8YF78|A0A2R8YF78_HUMAN,tr|A0A0D9SFB3|A0A0D9SFB3_HUMAN,tr|A0A2R8YFS5|A0A2R8YFS5_HUMAN,tr|A0A0D9SF53|A0A0D9SF53_HUMAN,tr|A0A087WVZ1|A0A087WVZ1_HUMAN,tr|A0A0J9YVQ7|A0A0J9YVQ7_HUMAN,tr|A0A2R8Y5G6|A0A2R8Y5G6_HUMAN,tr|A0A2R8Y7T2|A0A2R8Y7T2_HUMAN,tr|A0A0D9SG12|A0A0D9SG12_HUMAN,tr|F6S8Q4|F6S8Q4_HUMAN,tr|A0A2U3TZJ9|A0A2U3TZJ9_HUMAN,tr|A0A2R8Y4A4|A0A2R8Y4A4_HUMAN" 17 1370.5938 1.13 138924 5410 2 1370.591929 686.3042 ATP-dependent RNA helicase DDX3X OS=Homo sapiens OX=9606 GN=DDX3X PE=1 SV=3 9.75 1521.7 - 1.93E+06 - - - -1.3439 - 3.005 0.659 - 1131.6 1 2 0 -0.0018 14 0 0 0 2.50E+08 2.21E+08 - - - 6.6689 0.9587 221125_WJC_METTL3_EV_vs_WT_F10.05412.05412.2 0.518 20-Oct D.SQRPGAHLTVK.K "sp|Q32P51|RA1L2_HUMAN,sp|P09651|ROA1_HUMAN,tr|A0A7I2YQX9|A0A7I2YQX9_HUMAN,tr|F8W646|F8W646_HUMAN,tr|F8VZ49|F8VZ49_HUMAN,tr|A0A7I2V3R8|A0A7I2V3R8_HUMAN,tr|F8VTQ5|F8VTQ5_HUMAN,tr|F8W6I7|F8W6I7_HUMAN,tr|A0A7I2V2L6|A0A7I2V2L6_HUMAN,tr|A0A7I2V3W0|A0A7I2V3W0_HUMAN,tr|A0A7I2V5U9|A0A7I2V5U9_HUMAN" 11 1192.6677 1.65 138926 5412 2 1192.669737 597.3411 Heterogeneous nuclear ribonucleoprotein A1-like 2 OS=Homo sapiens OX=9606 GN=HNRNPA1L2 PE=2 SV=2 11 1522 - 1.15E+06 - - - 1.7457 - 2.026 0.327 - 375.5 1 1 0 0.0021 11 0 0 0 1.05E+07 6.34E+06 - - - 3.3656 1 221125_WJC_METTL3_EV_vs_WT_F10.05413.05413.2 1.54E-08 24-Oct K.C[160.03]PQPC[160.03]PPQQC[160.03]QQK.C "sp|P22531|SPR2E_HUMAN,sp|P35326|SPR2A_HUMAN,sp|P22532|SPR2D_HUMAN,sp|P35325|SPR2B_HUMAN" 4 1654.7014 999 138927 5413 2 1654.696542 828.358 Small proline-rich protein 2E OS=Homo sapiens OX=9606 GN=SPRR2E PE=2 SV=2 7.96 1522.1 - 331620 - - - -2.9455 - 2.421 0.693 - 295.6 1 2 0 -0.0049 13 0 0 0 2.76E+07 0.00E+00 - - - 6.4272 0.9572 221125_WJC_METTL3_EV_vs_WT_F10.05416.05416.2 1.17 12-Jun K.EQSIVEK[136.11].F "sp|Q86U44|MTA70_HUMAN,tr|H0YFV6|H0YFV6_HUMAN" 2 839.448 0.02 138928 5416 2 839.446551 420.7313 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 4.53 1522.5 - 7.85E+06 - - - -1.7238 - 1.292 0.024 - 250.7 1 2 0 -0.0014 7 0 0 0 3.95E+06 1.87E+08 - - - 0.0296 1 221125_WJC_METTL3_EV_vs_WT_F10.05417.05417.3 1.58E-09 19/52 K.C[160.03]AAPR[166.11]PPSSSPEQR[166.11].T "sp|Q5H9R7|PP6R3_HUMAN,tr|H7BXH2|H7BXH2_HUMAN,tr|E9PQP7|E9PQP7_HUMAN,tr|H0YEN2|H0YEN2_HUMAN,tr|E9PKF6|E9PKF6_HUMAN" 5 1558.7425 0.69 138929 5417 3 1558.738242 520.5881 Serine\threonine-protein phosphatase 6 regulatory subunit 3 OS=Homo sapiens OX=9606 GN=PPP6R3 PE=1 SV=2 8.25 1522.6 - 1.57E+06 - - - -2.7407 - 2.936 0.569 - 623.2 1 2 0 -0.0043 14 0 0 0 1.56E+07 2.24E+07 - - - 7.7449 0.9976 221125_WJC_METTL3_EV_vs_WT_F10.05418.05418.3 4.57E-06 18/64 S.RSGGGGGGGLGSGGSIR.S sp|P35527|K1C9_HUMAN 1 1387.6916 497.21 138930 5418 3 1387.691067 463.5712 "Keratin, type I cytoskeletal 9 OS=Homo sapiens OX=9606 GN=KRT9 PE=1 SV=3" 12 1522.7 - 1.69E+06 - - - -0.4108 - 2.77 0.515 - 388 1 1 0 -0.0006 17 0 0 0 1.20E+08 2.42E+05 - - - 6.8555 1 221125_WJC_METTL3_EV_vs_WT_F10.05419.05419.2 2.13E-06 17/36 R.GGSGGSHGGGSGFGGESGG.S "sp|P35527|K1C9_HUMAN,tr|K7EQQ3|K7EQQ3_HUMAN" 2 1463.5662 - 138931 5419 2 1463.562941 732.7904 "Keratin, type I cytoskeletal 9 OS=Homo sapiens OX=9606 GN=KRT9 PE=1 SV=3" 5.24 1522.8 - 922359 - - - -2.2008 - 2.79 0.635 - 558.4 1 1 0 -0.0032 19 0 0 0 - - - - - 6.2527 0.983 221125_WJC_METTL3_EV_vs_WT_F10.05420.05420.2 0.00351 20-Dec D.SQR[166.11]PGAHLTVK[136.11].K "sp|Q32P51|RA1L2_HUMAN,sp|P09651|ROA1_HUMAN,tr|A0A7I2YQX9|A0A7I2YQX9_HUMAN,tr|F8W646|F8W646_HUMAN,tr|F8VZ49|F8VZ49_HUMAN,tr|A0A7I2V3R8|A0A7I2V3R8_HUMAN,tr|F8VTQ5|F8VTQ5_HUMAN,tr|F8W6I7|F8W6I7_HUMAN,tr|A0A7I2V2L6|A0A7I2V2L6_HUMAN,tr|A0A7I2V3W0|A0A7I2V3W0_HUMAN,tr|A0A7I2V5U9|A0A7I2V5U9_HUMAN" 11 1210.6901 1.65 138932 5420 2 1210.688821 606.3523 Heterogeneous nuclear ribonucleoprotein A1-like 2 OS=Homo sapiens OX=9606 GN=HNRNPA1L2 PE=2 SV=2 11 1523 - 684299 - - - -1.0771 - 2.284 0.353 - 477.1 1 1 0 -0.0013 11 0 0 0 1.05E+07 6.34E+06 - - - 3.8822 1 221125_WJC_METTL3_EV_vs_WT_F10.05424.05424.3 4.75E-07 16/48 K.C[160.03]PQPC[160.03]PPQQC[160.03]QQK.C "sp|P22531|SPR2E_HUMAN,sp|P35326|SPR2A_HUMAN,sp|P22532|SPR2D_HUMAN,sp|P35325|SPR2B_HUMAN" 4 1654.7014 144.34 138934 5424 3 1654.701307 552.5744 Small proline-rich protein 2E OS=Homo sapiens OX=9606 GN=SPRR2E PE=2 SV=2 7.96 1523.4 - 1.45E+06 - - - -0.0659 - 2.461 0.586 - 401.3 1 2 0 -0.0001 13 0 0 0 2.14E+07 1.48E+05 - - - 7.515 0.9486 221125_WJC_METTL3_EV_vs_WT_F10.05425.05425.2 0.00906 22-Nov E.DSQRPGAHLTVK.K "sp|Q32P51|RA1L2_HUMAN,sp|P09651|ROA1_HUMAN,tr|A0A7I2YQX9|A0A7I2YQX9_HUMAN,tr|F8W646|F8W646_HUMAN,tr|F8VZ49|F8VZ49_HUMAN,tr|A0A7I2V3R8|A0A7I2V3R8_HUMAN,tr|F8VTQ5|F8VTQ5_HUMAN,tr|F8W6I7|F8W6I7_HUMAN,tr|A0A7I2V2L6|A0A7I2V2L6_HUMAN,tr|A0A7I2V3W0|A0A7I2V3W0_HUMAN,tr|A0A7I2V5U9|A0A7I2V5U9_HUMAN" 11 1307.6946 1.34 138935 5425 2 1307.695822 654.8546 Heterogeneous nuclear ribonucleoprotein A1-like 2 OS=Homo sapiens OX=9606 GN=HNRNPA1L2 PE=2 SV=2 8.75 1523.5 - 606167 - - - 0.936 - 2.292 0.199 - 245 1 1 0 0.0012 12 0 0 0 6.25E+06 4.67E+06 - - - 2.6928 0.9989 221125_WJC_METTL3_EV_vs_WT_F10.05426.05426.3 0.000497 Nov-36 R.DK[136.11]R[166.11]PEGYNLK[136.11].E "sp|P63151|2ABA_HUMAN,sp|Q00005|2ABB_HUMAN,sp|Q9Y2T4|2ABG_HUMAN,tr|A0A590UJY3|A0A590UJY3_HUMAN" 4 1244.6724 0.44 138936 5426 3 1244.671106 415.8981 Serine\threonine-protein phosphatase 2A 55 kDa regulatory subunit B alpha isoform OS=Homo sapiens OX=9606 GN=PPP2R2A PE=1 SV=1 8.5 1523.6 - 5.21E+06 - - - -1.0043 - 2.124 0.33 - 140 1 2 1 -0.0012 10 0 0 0 2.04E+07 4.62E+07 - - - 4.4188 0.9996 221125_WJC_METTL3_EV_vs_WT_F10.05429.05429.3 0.000259 Dec-32 R.R[166.11]ADDDR[166.11]FPR[166.11].R sp|Q14152|EIF3A_HUMAN 1 1176.5778 4.75 138939 5429 3 1176.575672 393.1999 Eukaryotic translation initiation factor 3 subunit A OS=Homo sapiens OX=9606 GN=EIF3A PE=1 SV=1 6.04 1523.7 - 2.03E+06 - - - -1.8333 - 2.13 0.437 - 233.1 1 2 1 -0.0022 9 0 0 0 1.53E+08 3.21E+07 - - - 5.6903 0.9998 221125_WJC_METTL3_EV_vs_WT_F10.05434.05434.3 5.52E-07 16/56 K.QHPVPPPAQNQNQVR[166.11].S "sp|Q15942|ZYX_HUMAN,tr|H0Y2Y8|H0Y2Y8_HUMAN" 2 1718.884 9.44 138944 5434 3 1718.880034 573.9686 Zyxin OS=Homo sapiens OX=9606 GN=ZYX PE=1 SV=1 9.76 1524.2 - 446677 - - - -2.3189 - 3.088 0.361 - 460.1 1 2 0 -0.004 15 0 0 0 7.18E+07 7.61E+06 - - - 5.5058 1 221125_WJC_METTL3_EV_vs_WT_F10.05435.05435.3 3.57E-10 15/60 R.KPLSGNSNSSGSESFK.F "sp|Q99590|SCAFB_HUMAN,tr|F8VXG7|F8VXG7_HUMAN" 2 1624.7693 0.97 138945 5435 3 1624.765611 542.597 Protein SCAF11 OS=Homo sapiens OX=9606 GN=SCAF11 PE=1 SV=2 8.59 1524.4 - 306392 - - - -2.2576 - 3.249 0.609 - 356.4 1 2 0 -0.0037 16 0 0 0 3.63E+07 3.75E+07 - - - 8.3522 0.997 221125_WJC_METTL3_EV_vs_WT_F10.05442.05442.3 0.000473 17/44 E.DSQR[166.11]PGAHLTVK[136.11].K "sp|Q32P51|RA1L2_HUMAN,sp|P09651|ROA1_HUMAN,tr|A0A7I2YQX9|A0A7I2YQX9_HUMAN,tr|F8W646|F8W646_HUMAN,tr|F8VZ49|F8VZ49_HUMAN,tr|A0A7I2V3R8|A0A7I2V3R8_HUMAN,tr|F8VTQ5|F8VTQ5_HUMAN,tr|F8W6I7|F8W6I7_HUMAN,tr|A0A7I2V2L6|A0A7I2V2L6_HUMAN,tr|A0A7I2V3W0|A0A7I2V3W0_HUMAN,tr|A0A7I2V5U9|A0A7I2V5U9_HUMAN" 11 1325.7171 1.29 138950 5442 3 1325.715632 442.913 Heterogeneous nuclear ribonucleoprotein A1-like 2 OS=Homo sapiens OX=9606 GN=HNRNPA1L2 PE=2 SV=2 8.75 1525 - 4.26E+06 - - - -1.0832 - 2.908 0.461 - 422.7 1 1 0 -0.0014 12 0 0 0 1.21E+08 9.38E+07 - - - 6.6382 1 221125_WJC_METTL3_EV_vs_WT_F10.05443.05443.3 4.92E-10 16/60 R.K[136.11]PLSGNSNSSGSESFK[136.11].F "sp|Q99590|SCAFB_HUMAN,tr|F8VXG7|F8VXG7_HUMAN" 2 1640.7977 0.99 138951 5443 3 1640.795618 547.9398 Protein SCAF11 OS=Homo sapiens OX=9606 GN=SCAF11 PE=1 SV=2 8.59 1525.1 - 1.32E+06 - - - -1.2561 - 3.465 0.472 - 375.7 1 2 0 -0.0021 16 0 0 0 3.52E+07 3.57E+07 - - - 6.9904 1 221125_WJC_METTL3_EV_vs_WT_F10.05444.05444.3 4.06E-11 25/64 R.ALGQAASDNSGPEDAKR.Q "sp|Q15155|NOMO1_HUMAN,sp|Q5JPE7|NOMO2_HUMAN,sp|P69849|NOMO3_HUMAN,tr|A0A7I2V3P4|A0A7I2V3P4_HUMAN,tr|A0A7I2V6B0|A0A7I2V6B0_HUMAN,tr|A0A7I2V4T6|A0A7I2V4T6_HUMAN,tr|A0A0G2JP90|A0A0G2JP90_HUMAN,tr|A0A087WTD5|A0A087WTD5_HUMAN,tr|A0A087X117|A0A087X117_HUMAN,tr|A0A0G2JN29|A0A0G2JN29_HUMAN,tr|A0A7I2V2Z5|A0A7I2V2Z5_HUMAN,tr|A0A087WW46|A0A087WW46_HUMAN,tr|H3BUC9|H3BUC9_HUMAN,tr|J3KN36|J3KN36_HUMAN" 14 1685.7969 1.52 138952 5444 3 1685.795103 562.9396 Nodal modulator 1 OS=Homo sapiens OX=9606 GN=NOMO1 PE=1 SV=5 4.56 1525.3 - 1.11E+06 - - - -1.0606 - 4.702 0.617 - 849 1 2 0 -0.0018 17 0 0 0 9.80E+06 6.45E+06 - - - 9.3291 0.9978 221125_WJC_METTL3_EV_vs_WT_F10.05445.05445.3 4.46E-06 16/64 S.RSGGGGGGGLGSGGSIR.S sp|P35527|K1C9_HUMAN 1 1387.6916 497.21 138953 5445 3 1387.690697 463.5712 "Keratin, type I cytoskeletal 9 OS=Homo sapiens OX=9606 GN=KRT9 PE=1 SV=3" 12 1525.3 - 7.65E+06 - - - -0.6774 - 2.968 0.512 - 304 1 1 0 -0.0009 17 0 0 0 1.20E+08 2.42E+05 - - - 6.9964 1 221125_WJC_METTL3_EV_vs_WT_F10.05446.05446.2 4.97E-06 Dec-34 R.GGSGGSHGGGSGFGGESG.G "sp|P35527|K1C9_HUMAN,tr|K7EQQ3|K7EQQ3_HUMAN" 2 1406.5447 - 138954 5446 2 1406.541456 704.2796 "Keratin, type I cytoskeletal 9 OS=Homo sapiens OX=9606 GN=KRT9 PE=1 SV=3" 5.24 1525.4 - 622576 - - - -2.3049 - 2.536 0.669 - 245.8 1 1 0 -0.0032 18 0 0 0 - - - - - 6.2691 0.9997 221125_WJC_METTL3_EV_vs_WT_F10.05452.05452.3 1.93E-05 15/32 R.RADDDRFPR.R sp|Q14152|EIF3A_HUMAN 1 1146.553 4.75 138959 5452 3 1146.551373 383.1916 Eukaryotic translation initiation factor 3 subunit A OS=Homo sapiens OX=9606 GN=EIF3A PE=1 SV=1 6.04 1526.3 - 1.13E+06 - - - -1.4356 - 2.058 0.458 - 481.7 1 2 1 -0.0016 9 0 0 0 1.53E+08 3.21E+07 - - - 5.821 0.9999 221125_WJC_METTL3_EV_vs_WT_F10.05454.05454.3 2.94E-07 13/36 K.NHEEEMKDLR.N "sp|P13645|K1C10_HUMAN,tr|A0A1B0GVI3|A0A1B0GVI3_HUMAN" 2 1299.5877 1363.81 138960 5454 3 1299.586681 434.2032 "Keratin, type I cytoskeletal 10 OS=Homo sapiens OX=9606 GN=KRT10 PE=1 SV=6" 4.83 1526.5 - 1.29E+07 - - - -0.8218 - 2.632 0.586 - 304.6 1 2 1 -0.0011 10 0 0 0 3.24E+09 2.37E+06 - - - 7.8993 1 221125_WJC_METTL3_EV_vs_WT_F10.05455.05455.2 6.34E-11 15/26 K.AQGTDNSDQSEIC[160.03]K.L "sp|Q15643|TRIPB_HUMAN,tr|G3V4R7|G3V4R7_HUMAN" 2 1551.6471 1.24 138961 5455 2 1551.645683 776.8308 Thyroid receptor-interacting protein 11 OS=Homo sapiens OX=9606 GN=TRIP11 PE=1 SV=3 4.03 1526.6 - 5.32E+06 - - - -0.9229 - 3.073 0.738 - 879.6 1 2 0 -0.0014 14 0 0 0 1.39E+08 1.12E+08 - - - 7.3087 1 221125_WJC_METTL3_EV_vs_WT_F10.05456.05456.3 1.25E-05 Nov-40 K.VSMHYSDPKPK.L sp|P98175|RBM10_HUMAN 1 1287.6282 2.76 138962 5456 3 1287.626217 430.2167 RNA-binding protein 10 OS=Homo sapiens OX=9606 GN=RBM10 PE=1 SV=3 8.48 1526.6 - 3.75E+06 - - - -1.5074 - 1.974 0.541 - 121.2 1 2 0 -0.0019 11 0 0 0 7.19E+07 2.60E+07 - - - 6.503 0.9909 221125_WJC_METTL3_EV_vs_WT_F10.05457.05457.3 1.73E-06 19/68 L.SRSGGGGGGGLGSGGSIR.S sp|P35527|K1C9_HUMAN 1 1474.7237 52.03 138963 5457 3 1474.722005 492.5818 "Keratin, type I cytoskeletal 9 OS=Homo sapiens OX=9606 GN=KRT9 PE=1 SV=3" 12 1526.7 - 1.97E+06 - - - -1.1263 - 2.79 0.55 - 362.8 1 1 1 -0.0017 18 0 0 0 9.02E+07 1.73E+06 - - - 7.2264 1 221125_WJC_METTL3_EV_vs_WT_F10.05460.05460.3 5.74E-17 24/60 R.IHEGC[160.03]EEPATHNALAK[136.11].L "sp|Q00610|CLH1_HUMAN,tr|A0A087WVQ6|A0A087WVQ6_HUMAN" 2 1783.8403 1.03 138966 5460 3 1783.840152 595.6207 Clathrin heavy chain 1 OS=Homo sapiens OX=9606 GN=CLTC PE=1 SV=5 5.33 1526.9 - 1.02E+06 - - - -0.0729 - 4.344 0.747 - 875.7 1 2 0 -0.0001 16 0 0 0 5.88E+07 5.69E+07 - - - 10.637 0.9915 221125_WJC_METTL3_EV_vs_WT_F10.05461.05461.3 0.17 Oct-36 K.HQASISELKR.N "sp|O43491|E41L2_HUMAN,tr|Q6R5J7|Q6R5J7_HUMAN,tr|E9PMV8|E9PMV8_HUMAN,tr|E9PMG5|E9PMG5_HUMAN,tr|H0Y5B0|H0Y5B0_HUMAN,tr|E9PN54|E9PN54_HUMAN,tr|Q6ZSX4|Q6ZSX4_HUMAN" 7 1167.636 999 138967 5461 3 1167.636125 390.2193 Band 4.1-like protein 2 OS=Homo sapiens OX=9606 GN=EPB41L2 PE=1 SV=1 8.75 1527 - 1.02E+06 - - - 0.0899 - 1.465 0.202 - 99.7 1 2 0 0.0001 10 0 0 0 6.07E+06 0.00E+00 - - - 1.9073 0.9999 221125_WJC_METTL3_EV_vs_WT_F10.05462.05462.3 0.000433 Dec-44 K.GLHSC[160.03]HIPGC[160.03]GK.V "sp|Q8IXZ3|SP8_HUMAN,sp|P0CG40|SP9_HUMAN,tr|A0A087X0Q6|A0A087X0Q6_HUMAN" 3 1321.602 0.01 138968 5462 3 1321.601422 441.5413 Transcription factor Sp8 OS=Homo sapiens OX=9606 GN=SP8 PE=1 SV=3 8.08 1527.1 - 1.01E+06 - - - -0.4071 - 2.197 0.393 - 246.6 1 2 0 -0.0005 12 0 0 0 1.45E+07 1.02E+09 - - - 5.1031 1 221125_WJC_METTL3_EV_vs_WT_F10.05464.05464.2 5.02E-09 17/30 R.SQSAAVTPSSTTSSTR[166.11].A "sp|Q16186|ADRM1_HUMAN,tr|A0A087WX59|A0A087WX59_HUMAN" 2 1576.7568 1.15 138970 5464 2 1576.756481 789.3857 Proteasomal ubiquitin receptor ADRM1 OS=Homo sapiens OX=9606 GN=ADRM1 PE=1 SV=2 9.47 1527.3 - 661347 - - - -0.2106 - 3.223 0.676 - 763.9 1 2 0 -0.0003 16 0 0 0 4.79E+07 4.15E+07 - - - 6.9111 0.9976 221125_WJC_METTL3_EV_vs_WT_F10.05466.05466.3 0.175 Sep-52 R.QSSGASSSSFSSSR[166.11].A "sp|O00571|DDX3X_HUMAN,tr|A0A2R8YFR4|A0A2R8YFR4_HUMAN,tr|A0A2R8YCW1|A0A2R8YCW1_HUMAN,tr|A0A2R8YDT5|A0A2R8YDT5_HUMAN,tr|A0A2R8Y645|A0A2R8Y645_HUMAN,tr|A0A2R8YF78|A0A2R8YF78_HUMAN,tr|A0A0D9SFB3|A0A0D9SFB3_HUMAN,tr|A0A2R8YFS5|A0A2R8YFS5_HUMAN,tr|A0A0D9SF53|A0A0D9SF53_HUMAN,tr|A0A087WVZ1|A0A087WVZ1_HUMAN,tr|A0A0J9YVQ7|A0A0J9YVQ7_HUMAN,tr|A0A2R8Y5G6|A0A2R8Y5G6_HUMAN,tr|A0A2R8Y7T2|A0A2R8Y7T2_HUMAN,tr|A0A0D9SG12|A0A0D9SG12_HUMAN,tr|F6S8Q4|F6S8Q4_HUMAN,tr|A0A2U3TZJ9|A0A2U3TZJ9_HUMAN,tr|A0A2R8Y4A4|A0A2R8Y4A4_HUMAN" 17 1370.5938 1.14 138972 5466 3 1370.59317 457.8719 ATP-dependent RNA helicase DDX3X OS=Homo sapiens OX=9606 GN=DDX3X PE=1 SV=3 9.75 1527.6 - 404038 - - - -0.4385 - 1.316 0.309 - 65.9 1 2 0 -0.0006 14 0 0 0 3.10E+06 2.73E+06 - - - 2.7146 0.9985 221125_WJC_METTL3_EV_vs_WT_F10.05470.05470.2 0.000308 24-Jun R.C[160.03]GETGHVAINC[160.03]SK.T sp|P62633|CNBP_HUMAN 1 1431.6235 0.42 138976 5470 2 1431.627585 716.819 CCHC-type zinc finger nucleic acid binding protein OS=Homo sapiens OX=9606 GN=CNBP PE=1 SV=1 6.73 1528.1 - 208978 - - - 2.8653 - 1.221 0.52 - 72.6 1 2 0 0.0041 13 0 0 0 1.77E+06 4.24E+06 - - - 3.3929 1 221125_WJC_METTL3_EV_vs_WT_F10.05474.05474.2 5.51E-09 13/26 K.AQGTDNSDQSEIC[160.03]K[136.11].L "sp|Q15643|TRIPB_HUMAN,tr|G3V4R7|G3V4R7_HUMAN" 2 1559.6613 1.24 138978 5474 2 1559.659673 780.8379 Thyroid receptor-interacting protein 11 OS=Homo sapiens OX=9606 GN=TRIP11 PE=1 SV=3 4.03 1528.6 - 1.44E+07 - - - -1.0528 - 2.764 0.725 - 569.9 1 2 0 -0.0016 14 0 0 0 1.39E+08 1.12E+08 - - - 6.9466 1 221125_WJC_METTL3_EV_vs_WT_F10.05475.05475.4 1.45E-10 16/90 R.IHEGC[160.03]EEPATHNALAK[136.11].L "sp|Q00610|CLH1_HUMAN,tr|A0A087WVQ6|A0A087WVQ6_HUMAN" 2 1783.8403 1.09 138979 5475 4 1783.83686 446.9673 Clathrin heavy chain 1 OS=Homo sapiens OX=9606 GN=CLTC PE=1 SV=5 5.33 1528.7 - 1.12E+07 - - - -1.9183 - 3.355 0.655 - 300 1 2 0 -0.0034 16 0 0 0 8.56E+07 7.85E+07 - - - 5.3526 1 221125_WJC_METTL3_EV_vs_WT_F10.05476.05476.4 6.83E-08 19/90 R.IHEGC[160.03]EEPATHNALAK.L "sp|Q00610|CLH1_HUMAN,tr|A0A087WVQ6|A0A087WVQ6_HUMAN" 2 1775.8261 1.09 138980 5476 4 1775.823385 444.9638 Clathrin heavy chain 1 OS=Homo sapiens OX=9606 GN=CLTC PE=1 SV=5 5.33 1528.7 - 1.17E+07 - - - -1.5187 - 3.457 0.609 - 446.3 1 2 0 -0.0027 16 0 0 0 8.56E+07 7.85E+07 - - - 4.9629 1 221125_WJC_METTL3_EV_vs_WT_F10.05478.05478.3 7.93E-16 22/60 R.IHEGC[160.03]EEPATHNALAK.L "sp|Q00610|CLH1_HUMAN,tr|A0A087WVQ6|A0A087WVQ6_HUMAN" 2 1775.8261 1.03 138982 5478 3 1775.824118 592.9493 Clathrin heavy chain 1 OS=Homo sapiens OX=9606 GN=CLTC PE=1 SV=5 5.33 1528.8 - 6.33E+06 - - - -1.106 - 3.963 0.707 - 774.9 1 2 0 -0.002 16 0 0 0 5.88E+07 5.69E+07 - - - 9.955 1 221125_WJC_METTL3_EV_vs_WT_F10.05480.05480.2 6.94E-09 14/18 K.NHEEEMKDLR.N "sp|P13645|K1C10_HUMAN,tr|A0A1B0GVI3|A0A1B0GVI3_HUMAN" 2 1299.5877 999 138984 5480 2 1299.586482 650.8012 "Keratin, type I cytoskeletal 10 OS=Homo sapiens OX=9606 GN=KRT10 PE=1 SV=6" 4.83 1528.9 - 4.47E+06 - - - -0.9749 - 2.544 0.606 - 694.7 1 2 1 -0.0013 10 0 0 0 9.40E+07 0.00E+00 - - - 6.1229 1 221125_WJC_METTL3_EV_vs_WT_F10.05481.05481.3 6.37E-13 22/64 R.NAASSEEAK[136.11]AEETGGGK[136.11].E "sp|P39880|CUX1_HUMAN,tr|A0A2R8Y852|A0A2R8Y852_HUMAN,tr|A0A2R8YDI1|A0A2R8YDI1_HUMAN" 3 1650.7668 1.82 138985 5481 3 1650.764828 551.2629 Homeobox protein cut-like 1 OS=Homo sapiens OX=9606 GN=CUX1 PE=1 SV=3 4.49 1528.9 - 3.78E+06 - - - -1.1782 - 4.239 0.675 - 716 1 2 1 -0.0019 17 0 0 0 4.25E+07 2.33E+07 - - - 9.7139 1 221125_WJC_METTL3_EV_vs_WT_F10.05482.05482.2 3.06E-08 16/30 R.SQSAAVTPSSTTSSTR.A "sp|Q16186|ADRM1_HUMAN,tr|A0A087WX59|A0A087WX59_HUMAN" 2 1566.7485 1.15 138986 5482 2 1566.746958 784.3815 Proteasomal ubiquitin receptor ADRM1 OS=Homo sapiens OX=9606 GN=ADRM1 PE=1 SV=2 9.47 1529 - 2.46E+06 - - - -1.0116 - 3.267 0.678 - 670.4 1 2 0 -0.0016 16 0 0 0 4.79E+07 4.15E+07 - - - 6.9588 1 221125_WJC_METTL3_EV_vs_WT_F10.05483.05483.3 0.00178 17/48 R.TPLTSADEHVHSK.L "sp|Q5SW79|CE170_HUMAN,tr|H0Y2V6|H0Y2V6_HUMAN" 2 1420.6947 0.98 138987 5483 3 1420.692959 474.5722 Centrosomal protein of 170 kDa OS=Homo sapiens OX=9606 GN=CEP170 PE=1 SV=1 5.92 1529 - 1.94E+06 - - - -1.1952 - 3.493 0.501 - 508.2 1 2 0 -0.0017 13 0 0 0 2.72E+07 2.78E+07 - - - 7.5164 0.9999 221125_WJC_METTL3_EV_vs_WT_F10.05484.05484.3 1.99E-05 13/44 K.KGPGLAVQSGDK.T sp|Q96PK6|RBM14_HUMAN 1 1155.6248 1.09 138988 5484 3 1155.623302 386.2155 RNA-binding protein 14 OS=Homo sapiens OX=9606 GN=RBM14 PE=1 SV=2 8.59 1529.1 - 1.70E+06 - - - -1.285 - 2.179 0.445 - 231.5 1 2 0 -0.0015 12 0 0 0 1.25E+07 1.15E+07 - - - 5.6598 0.9998 221125_WJC_METTL3_EV_vs_WT_F10.05485.05485.3 0.0382 15/36 R.R[166.11]K[136.11]EEIEAQIK[136.11].A "sp|O00233|PSMD9_HUMAN,tr|J3KN29|J3KN29_HUMAN,tr|F5H5V4|F5H5V4_HUMAN,tr|F5GX23|F5GX23_HUMAN,tr|F5H7X1|F5H7X1_HUMAN" 5 1268.7299 0.78 138989 5485 3 1268.728835 423.9172 26S proteasome non-ATPase regulatory subunit 9 OS=Homo sapiens OX=9606 GN=PSMD9 PE=1 SV=3 6.23 1529.2 - 1.42E+06 - - - -0.8166 - 2.746 0.388 - 380.2 1 2 1 -0.001 10 0 0 0 8.06E+06 1.03E+07 - - - 5.8156 1 221125_WJC_METTL3_EV_vs_WT_F10.05487.05487.3 0.000139 15/52 K.AQGTDNSDQSEIC[160.03]K[136.11].L "sp|Q15643|TRIPB_HUMAN,tr|G3V4R7|G3V4R7_HUMAN" 2 1559.6613 1.27 138991 5487 3 1559.662297 520.8944 Thyroid receptor-interacting protein 11 OS=Homo sapiens OX=9606 GN=TRIP11 PE=1 SV=3 4.03 1529.4 - 1.15E+06 - - - 0.6296 - 2.546 0.459 - 340.4 1 2 0 0.001 14 0 0 0 8.55E+06 6.72E+06 - - - 6.1407 0.9333 221125_WJC_METTL3_EV_vs_WT_F10.05489.05489.3 0.0892 Sep-48 K.TNGHC[160.03]DPEIQTTR.E sp|Q9P2B4|CT2NL_HUMAN 1 1527.6736 0.7 138993 5489 3 1527.676097 510.2318 CTTNBP2 N-terminal-like protein OS=Homo sapiens OX=9606 GN=CTTNBP2NL PE=1 SV=2 5.29 1529.6 - 700320 - - - 1.6319 - 1.147 0.181 - 39.5 1 2 0 0.0025 13 0 0 0 4.33E+06 6.14E+06 - - - 0.9291 0.9293 221125_WJC_METTL3_EV_vs_WT_F10.05490.05490.2 5.00E-05 Dec-34 L.SRSGGGGGGGLGSGGSIR.S sp|P35527|K1C9_HUMAN 1 1474.7237 999 138994 5490 2 1474.7233 738.3691 "Keratin, type I cytoskeletal 9 OS=Homo sapiens OX=9606 GN=KRT9 PE=1 SV=3" 12 1529.7 - 519887 - - - -0.2482 - 2.413 0.51 - 54.6 1 1 1 -0.0004 18 0 0 0 4.33E+06 0.00E+00 - - - 4.9734 1 221125_WJC_METTL3_EV_vs_WT_F10.05493.05493.2 6.82E-09 16/32 R.NAASSEEAKAEETGGGK.E "sp|P39880|CUX1_HUMAN,tr|A0A2R8Y852|A0A2R8Y852_HUMAN,tr|A0A2R8YDI1|A0A2R8YDI1_HUMAN" 3 1634.7384 3.52 138997 5493 2 1634.738545 818.3765 Homeobox protein cut-like 1 OS=Homo sapiens OX=9606 GN=CUX1 PE=1 SV=3 4.49 1530 - 423664 - - - 0.1052 - 3.367 0.669 - 854.2 1 2 1 0.0002 17 0 0 0 2.91E+06 8.28E+05 - - - 6.9669 1 221125_WJC_METTL3_EV_vs_WT_F10.05497.05497.3 1.60E-07 20/48 R.TPLTSADEHVHSK[136.11].L "sp|Q5SW79|CE170_HUMAN,tr|H0Y2V6|H0Y2V6_HUMAN" 2 1428.7089 0.98 138999 5497 3 1428.7066 477.2436 Centrosomal protein of 170 kDa OS=Homo sapiens OX=9606 GN=CEP170 PE=1 SV=1 5.92 1530.5 - 2.62E+06 - - - -1.5797 - 3.7 0.529 - 675.5 1 2 0 -0.0023 13 0 0 0 2.74E+07 2.80E+07 - - - 7.9845 1 221125_WJC_METTL3_EV_vs_WT_F10.05498.05498.3 2.41E-09 16/44 K.KEETQPPVALKK.E sp|Q8NC51|PAIRB_HUMAN 1 1366.782 0.82 139000 5498 3 1366.778692 456.6013 Plasminogen activator inhibitor 1 RNA-binding protein OS=Homo sapiens OX=9606 GN=SERBP1 PE=1 SV=2 8.5 1530.6 - 2.63E+06 - - - -2.432 - 2.719 0.568 - 423.6 1 2 0 -0.0033 12 0 0 0 3.40E+07 4.15E+07 - - - 7.6443 1 221125_WJC_METTL3_EV_vs_WT_F10.05500.05500.3 2.03E-05 14/48 R.VEAKPEVQSQPPR.V "sp|Q9UN86|G3BP2_HUMAN,tr|A0A7I2V3E2|A0A7I2V3E2_HUMAN,tr|A0A7I2V647|A0A7I2V647_HUMAN,tr|A0A7I2V3Z6|A0A7I2V3Z6_HUMAN,tr|A0A7I2YQD9|A0A7I2YQD9_HUMAN,tr|A0A7I2V382|A0A7I2V382_HUMAN,tr|A0A7I2V547|A0A7I2V547_HUMAN,tr|A0A7I2V3P9|A0A7I2V3P9_HUMAN" 8 1463.7732 1.61 139002 5500 3 1463.773844 488.9317 Ras GTPase-activating protein-binding protein 2 OS=Homo sapiens OX=9606 GN=G3BP2 PE=1 SV=2 6.11 1530.7 - 2.50E+06 - - - 0.4113 - 2.722 0.473 - 292 1 2 0 0.0006 13 0 0 0 2.02E+07 1.26E+07 - - - 6.5283 0.9999 221125_WJC_METTL3_EV_vs_WT_F10.05509.05509.3 0.00783 14/44 K.K[136.11]EETQPPVALK[136.11]K[136.11].E sp|Q8NC51|PAIRB_HUMAN 1 1390.8246 0.82 139009 5509 3 1390.821731 464.6155 Plasminogen activator inhibitor 1 RNA-binding protein OS=Homo sapiens OX=9606 GN=SERBP1 PE=1 SV=2 8.5 1531.6 - 5.16E+06 - - - -2.0743 - 2.524 0.436 - 305.6 1 2 0 -0.0029 12 0 0 0 3.40E+07 4.15E+07 - - - 5.9665 0.9803 221125_WJC_METTL3_EV_vs_WT_F10.05517.05517.3 0.201 Sep-68 R.GPSGSASSR[166.11]PGVSATPPK[136.11].S sp|Q66K74|MAP1S_HUMAN 1 1656.855 0.69 139017 5517 3 1656.852333 553.2923 Microtubule-associated protein 1S OS=Homo sapiens OX=9606 GN=MAP1S PE=1 SV=2 11 1532.4 - 630952 - - - -1.6205 - 1.623 0.166 - 77.5 1 2 0 -0.0027 18 0 0 0 5.20E+06 7.49E+06 - - - 1.5959 1 221125_WJC_METTL3_EV_vs_WT_F10.05521.05521.3 3.41E-08 16/52 K.RPSQEEDTQSIGPK.V "sp|Q16526|CRY1_HUMAN,tr|H0YHT0|H0YHT0_HUMAN" 2 1570.7587 2.22 139019 5521 3 1570.757632 524.5935 Cryptochrome-1 OS=Homo sapiens OX=9606 GN=CRY1 PE=1 SV=1 4.68 1532.8 - 2.98E+06 - - - -0.6888 - 3.362 0.576 - 467.2 1 2 0 -0.0011 14 0 0 0 2.31E+07 1.04E+07 - - - 8.1839 0.9968 221125_WJC_METTL3_EV_vs_WT_F10.05527.05527.3 0.0146 Oct-40 K.ETAKPKPDPFK.G "sp|O43823|AKAP8_HUMAN,tr|A0A7P0T893|A0A7P0T893_HUMAN" 2 1256.6765 0.9 139025 5527 3 1256.677708 419.8994 A-kinase anchor protein 8 OS=Homo sapiens OX=9606 GN=AKAP8 PE=1 SV=1 8.59 1533.4 - 587122 - - - 0.9708 - 1.883 0.201 - 82.9 1 2 0 0.0012 11 0 0 0 1.23E+07 1.37E+07 - - - 2.5785 1 221125_WJC_METTL3_EV_vs_WT_F10.05529.05529.3 1.01E-06 13/68 K.AVETAAAHGSKPNVYANR.G sp|P22735|TGM1_HUMAN 1 1854.9337 999 139027 5529 3 1854.932068 619.3185 Protein-glutamine gamma-glutamyltransferase K OS=Homo sapiens OX=9606 GN=TGM1 PE=1 SV=4 8.64 1533.6 - 415745 - - - -0.8577 - 2.724 0.554 - 151.8 1 2 0 -0.0016 18 0 0 0 2.61E+06 0.00E+00 - - - 7.2114 0.9999 221125_WJC_METTL3_EV_vs_WT_F10.05539.05539.3 1.71E-05 Dec-44 K.AGLTDQVSHHAR.L sp|Q8NHH9|ATLA2_HUMAN 1 1290.6429 0.49 139035 5539 3 1290.642161 431.2216 Atlastin-2 OS=Homo sapiens OX=9606 GN=ATL2 PE=1 SV=2 6.96 1534.9 - 1.63E+06 - - - -0.5695 - 2.358 0.408 - 284.9 1 2 0 -0.0007 12 0 0 0 1.38E+07 2.82E+07 - - - 5.4663 1 221125_WJC_METTL3_EV_vs_WT_F10.05541.05541.3 1.72E-08 Dec-52 K.R[166.11]PSQEEDTQSIGPK[136.11].V "sp|Q16526|CRY1_HUMAN,tr|H0YHT0|H0YHT0_HUMAN" 2 1588.7812 2.22 139037 5541 3 1588.782162 530.601 Cryptochrome-1 OS=Homo sapiens OX=9606 GN=CRY1 PE=1 SV=1 4.68 1535.1 - 1.80E+06 - - - 0.6156 - 2.813 0.603 - 270 1 2 0 0.001 14 0 0 0 2.31E+07 1.04E+07 - - - 8.0111 0.999 221125_WJC_METTL3_EV_vs_WT_F10.05543.05543.3 0.00703 14/40 R.QQQQLLQQQHK.L "sp|P35712|SOX6_HUMAN,sp|P35711|SOX5_HUMAN,sp|Q9UN79|SOX13_HUMAN,tr|F5H0I3|F5H0I3_HUMAN,tr|H0YDQ5|H0YDQ5_HUMAN,tr|I3L0A5|I3L0A5_HUMAN" 6 1405.7426 1.94 139039 5543 3 1405.745955 469.5881 Transcription factor SOX-6 OS=Homo sapiens OX=9606 GN=SOX6 PE=1 SV=3 8.76 1535.2 - 678652 - - - 2.3795 - 2.126 0.298 - 336.8 1 2 0 0.0033 11 0 0 0 8.40E+06 4.33E+06 - - - 4.0042 0.9945 221125_WJC_METTL3_EV_vs_WT_F10.05545.05545.3 0.193 Oct-36 K.IKELDHNISK.H sp|O95347|SMC2_HUMAN 1 1195.6561 0.49 139041 5545 3 1195.657575 399.5593 Structural maintenance of chromosomes protein 2 OS=Homo sapiens OX=9606 GN=SMC2 PE=1 SV=2 6.75 1535.5 - 455732 - - - 1.2445 - 1.806 0.276 - 90.1 1 2 1 0.0015 10 0 0 0 1.80E+06 3.71E+06 - - - 3.343 0.9987 221125_WJC_METTL3_EV_vs_WT_F10.05547.05547.3 0.000288 Oct-52 R.MVQEAEK[136.11]YK[136.11]AEDEK[136.11].Q "sp|P11142|HSP7C_HUMAN,tr|E9PNE6|E9PNE6_HUMAN,tr|A8K7Q2|A8K7Q2_HUMAN,tr|E9PKE3|E9PKE3_HUMAN,tr|E9PM13|E9PM13_HUMAN,tr|E9PS65|E9PS65_HUMAN" 6 1720.8404 -1 139043 5547 3 1720.843041 574.6207 Heat shock cognate 71 kDa protein OS=Homo sapiens OX=9606 GN=HSPA8 PE=1 SV=1 4.58 1535.7 - 331866 - - - 1.5336 - 1.793 0.404 - 82.1 1 2 2 0.0026 14 0 0 0 0.00E+00 0.00E+00 - - - 4.5952 0.9992 221125_WJC_METTL3_EV_vs_WT_F10.05548.05548.3 0.00126 16/40 R.QQQQLLQQQHK[136.11].L "sp|P35712|SOX6_HUMAN,sp|P35711|SOX5_HUMAN,sp|Q9UN79|SOX13_HUMAN,tr|F5H0I3|F5H0I3_HUMAN,tr|H0YDQ5|H0YDQ5_HUMAN,tr|I3L0A5|I3L0A5_HUMAN" 6 1413.7568 1.94 139044 5548 3 1413.76179 472.2595 Transcription factor SOX-6 OS=Homo sapiens OX=9606 GN=SOX6 PE=1 SV=3 8.76 1535.9 - 284134 - - - 3.5225 - 2.19 0.367 - 523.3 1 2 0 0.005 11 0 0 0 8.40E+06 4.33E+06 - - - 4.8572 1 221125_WJC_METTL3_EV_vs_WT_F10.05551.05551.3 9.01E-08 22/60 K.QVQPQVQPQAHSQGPR[166.11].Q "sp|Q9ULV3|CIZ1_HUMAN,tr|Q5SYW2|Q5SYW2_HUMAN,tr|F5H2X7|F5H2X7_HUMAN,tr|H0Y5D5|H0Y5D5_HUMAN,tr|Q9BTG3|Q9BTG3_HUMAN" 5 1793.916 3.13 139047 5551 3 1793.921009 598.9793 Cip1-interacting zinc finger protein OS=Homo sapiens OX=9606 GN=CIZ1 PE=1 SV=2 9.76 1536.3 - 209640 - - - 2.7655 - 3.881 0.602 - 682.5 1 2 0 0.005 16 0 0 0 9.51E+07 3.04E+07 - - - 8.7299 1 221125_WJC_METTL3_EV_vs_WT_F10.05552.05552.2 2.21E-09 13/34 G.SYGGGGSGGGYGGGSGSR.G "sp|P35527|K1C9_HUMAN,tr|K7EQQ3|K7EQQ3_HUMAN" 2 1475.6025 -1 139048 5552 2 1475.601799 738.8086 "Keratin, type I cytoskeletal 9 OS=Homo sapiens OX=9606 GN=KRT9 PE=1 SV=3" 8.31 1536.4 - 138553 - - - -0.5076 - 2.525 0.79 - 397.6 1 1 0 -0.0007 18 0 0 0 0.00E+00 0.00E+00 - - - 7.1529 1 221125_WJC_METTL3_EV_vs_WT_F10.05557.05557.3 2.57E-06 23/60 K.QVQPQVQPQAHSQGPR.Q "sp|Q9ULV3|CIZ1_HUMAN,tr|Q5SYW2|Q5SYW2_HUMAN,tr|F5H2X7|F5H2X7_HUMAN,tr|H0Y5D5|H0Y5D5_HUMAN,tr|Q9BTG3|Q9BTG3_HUMAN" 5 1783.9078 3.13 139052 5557 3 1783.910377 595.6432 Cip1-interacting zinc finger protein OS=Homo sapiens OX=9606 GN=CIZ1 PE=1 SV=2 9.76 1536.9 - 3.78E+06 - - - 1.4569 - 3.754 0.572 - 639.3 1 2 0 0.0026 16 0 0 0 9.51E+07 3.04E+07 - - - 8.3107 0.9999 221125_WJC_METTL3_EV_vs_WT_F10.05558.05558.3 4.28E-05 14/44 K.AGLTDQVSHHAR[166.11].L sp|Q8NHH9|ATLA2_HUMAN 1 1300.6512 2.44 139053 5558 3 1300.653053 434.5577 Atlastin-2 OS=Homo sapiens OX=9606 GN=ATL2 PE=1 SV=2 6.96 1537 - 2.01E+06 - - - 1.4508 - 2.492 0.457 - 345.6 1 2 0 0.0019 12 0 0 0 7.52E+07 3.08E+07 - - - 6.1655 0.9997 221125_WJC_METTL3_EV_vs_WT_F10.05559.05559.3 0.000379 Nov-48 K.GVQLQTHPNVDK[136.11]K[136.11].L "sp|P48444|COPD_HUMAN,tr|B0YIW6|B0YIW6_HUMAN" 2 1478.8176 0.68 139054 5559 3 1478.820005 493.9465 Coatomer subunit delta OS=Homo sapiens OX=9606 GN=ARCN1 PE=1 SV=1 8.6 1537 - 1.72E+06 - - - 1.6087 - 2.129 0.347 - 109.7 1 2 0 0.0024 13 0 0 0 3.33E+06 4.88E+06 - - - 4.4568 1 221125_WJC_METTL3_EV_vs_WT_F10.05561.05561.3 1.37E-13 16/48 K.HEC[160.03]QANGPEDLNR.A sp|P60981|DEST_HUMAN 1 1538.6532 1.83 139056 5561 3 1538.653274 513.8917 Destrin OS=Homo sapiens OX=9606 GN=DSTN PE=1 SV=3 4.65 1537.2 - 1.15E+06 - - - 0.0461 - 3.319 0.708 - 583.1 1 2 0 0.0001 13 0 0 0 4.85E+07 2.65E+07 - - - 9.6861 0.9997 221125_WJC_METTL3_EV_vs_WT_F10.05562.05562.3 0.000322 Nov-48 K.GVQLQTHPNVDKK.L "sp|P48444|COPD_HUMAN,tr|B0YIW6|B0YIW6_HUMAN" 2 1462.7892 0.68 139057 5562 3 1462.791301 488.6037 Coatomer subunit delta OS=Homo sapiens OX=9606 GN=ARCN1 PE=1 SV=1 8.6 1537.2 - 995980 - - - 1.4185 - 1.808 0.385 - 84.5 1 2 0 0.0021 13 0 0 0 3.33E+06 4.88E+06 - - - 4.4375 0.9721 221125_WJC_METTL3_EV_vs_WT_F10.05564.05564.3 0.118 Nov-36 K.VQVSYK[136.11]GETK[136.11].A "sp|P0DMV8|HS71A_HUMAN,sp|P0DMV9|HS71B_HUMAN,tr|A0A0G2JIW1|A0A0G2JIW1_HUMAN" 3 1153.6314 0.04 139059 5564 3 1153.635496 385.5511 Heat shock 70 kDa protein 1A OS=Homo sapiens OX=9606 GN=HSPA1A PE=1 SV=1 8.47 1537.4 - 911155 - - - 3.5601 - 1.982 0.244 - 206.7 1 2 1 0.0041 10 0 0 0 4.84E+05 1.10E+07 - - - 3.2571 0.9999 221125_WJC_METTL3_EV_vs_WT_F10.05565.05565.3 0.000308 13/44 K.NILDSK[136.11]PTANK[136.11]K[136.11].C "sp|Q9ULV4|COR1C_HUMAN,tr|H0YHL7|H0YHL7_HUMAN,tr|B4E3S0|B4E3S0_HUMAN" 3 1351.7886 0.74 139060 5565 3 1351.790555 451.6035 Coronin-1C OS=Homo sapiens OX=9606 GN=CORO1C PE=1 SV=1 9.7 1537.5 - 666270 - - - 1.4721 - 2.182 0.422 - 137.9 1 2 0 0.002 12 0 0 0 2.38E+06 3.19E+06 - - - 5.407 0.9996 221125_WJC_METTL3_EV_vs_WT_F10.05569.05569.3 6.66E-05 Oct-48 K.ETEENKELTDTC[160.03]K.E sp|Q92922|SMRC1_HUMAN 1 1595.6985 1.21 139064 5569 3 1595.701154 532.9068 SWI\SNF complex subunit SMARCC1 OS=Homo sapiens OX=9606 GN=SMARCC1 PE=1 SV=3 4.25 1537.9 - 380492 - - - 1.6745 - 1.993 0.487 - 191.1 1 2 1 0.0027 13 0 0 0 2.02E+06 1.67E+06 - - - 5.8386 0.9999 221125_WJC_METTL3_EV_vs_WT_F10.05578.05578.3 0.000154 15/40 K.HKSETDTSLIR.G sp|P40227|TCPZ_HUMAN 1 1285.6626 0.42 139072 5578 3 1285.663619 429.5615 T-complex protein 1 subunit zeta OS=Homo sapiens OX=9606 GN=CCT6A PE=1 SV=3 6.75 1539 - 1.42E+07 - - - 0.77 - 2.357 0.534 - 517 1 2 1 0.001 11 0 0 0 2.01E+08 4.83E+08 - - - 6.929 1 221125_WJC_METTL3_EV_vs_WT_F10.05583.05583.3 1.25E-05 13/44 K.THLSLSHNPEQK[136.11].G "sp|P11586|C1TC_HUMAN,tr|F5H2F4|F5H2F4_HUMAN,tr|V9GZ78|V9GZ78_HUMAN,tr|V9GYY3|V9GYY3_HUMAN,tr|A0A494C1T2|A0A494C1T2_HUMAN" 5 1397.7143 3.43 139077 5583 3 1397.714187 466.912 "C-1-tetrahydrofolate synthase, cytoplasmic OS=Homo sapiens OX=9606 GN=MTHFD1 PE=1 SV=4" 6.61 1539.2 - 1.05E+06 - - - -0.0644 - 2.539 0.497 - 177.4 1 2 0 -0.0001 12 0 0 0 3.48E+07 1.01E+07 - - - 6.6638 0.9999 221125_WJC_METTL3_EV_vs_WT_F10.05584.05584.3 0.0318 16/56 R.AGFR[166.11]PVEAGGQHGGR[166.11].S sp|O15234|CASC3_HUMAN 1 1514.7605 1.22 139078 5584 3 1514.757555 505.9275 Protein CASC3 OS=Homo sapiens OX=9606 GN=CASC3 PE=1 SV=2 9.65 1539.3 - 927895 - - - -1.9752 - 2.811 0.444 - 199.9 1 2 0 -0.003 15 0 0 0 6.84E+06 5.59E+06 - - - 6.1862 1 221125_WJC_METTL3_EV_vs_WT_F10.05585.05585.3 3.26E-06 19/60 K.VVNANQNASPNVPGKR.G "sp|Q8IWI9|MGAP_HUMAN,tr|H3BP52|H3BP52_HUMAN" 2 1663.8754 1.71 139079 5585 3 1663.87626 555.6324 MAX gene-associated protein OS=Homo sapiens OX=9606 GN=MGA PE=1 SV=4 11 1539.4 - 840681 - - - 0.5072 - 2.866 0.504 - 364.9 1 2 0 0.0008 16 0 0 0 7.86E+06 4.61E+06 - - - 6.8605 0.9979 221125_WJC_METTL3_EV_vs_WT_F10.05586.05586.2 0.0471 17/20 K.HK[136.11]SETDTSLIR[166.11].G sp|P40227|TCPZ_HUMAN 1 1303.6851 0.37 139080 5586 2 1303.684808 652.8498 T-complex protein 1 subunit zeta OS=Homo sapiens OX=9606 GN=CCT6A PE=1 SV=3 6.75 1539.5 - 801933 - - - -0.2232 - 2.309 0.387 - 737.3 1 2 1 -0.0003 11 0 0 0 5.19E+06 1.39E+07 - - - 4.1631 1 221125_WJC_METTL3_EV_vs_WT_F10.05587.05587.3 4.89E-10 18/60 K.VVNANQNASPNVPGK[136.11]R[166.11].G "sp|Q8IWI9|MGAP_HUMAN,tr|H3BP52|H3BP52_HUMAN" 2 1681.8979 1.64 139081 5587 3 1681.898449 561.6399 MAX gene-associated protein OS=Homo sapiens OX=9606 GN=MGA PE=1 SV=4 11 1539.7 - 716220 - - - 0.3347 - 3.092 0.611 - 344.1 1 2 0 0.0006 16 0 0 0 7.54E+06 4.61E+06 - - - 8.2483 0.9913 221125_WJC_METTL3_EV_vs_WT_F10.05588.05588.2 0.205 18-Sep K.VQVSYK[136.11]GETK[136.11].A "sp|P0DMV8|HS71A_HUMAN,sp|P0DMV9|HS71B_HUMAN,tr|A0A0G2JIW1|A0A0G2JIW1_HUMAN" 3 1153.6314 -1 139082 5588 2 1153.632701 577.823 Heat shock 70 kDa protein 1A OS=Homo sapiens OX=9606 GN=HSPA1A PE=1 SV=1 8.47 1539.8 - 547543 - - - 1.1373 - 1.754 0.313 - 362.6 1 2 1 0.0013 10 0 0 0 0.00E+00 0.00E+00 - - - 2.9208 1 221125_WJC_METTL3_EV_vs_WT_F10.05590.05590.3 1.59E-08 13/52 K.FNC[160.03]EENQHSDSC[160.03]YK[136.11].L sp|Q96BR5|COA7_HUMAN 1 1824.6923 0.67 139084 5590 3 1824.69036 609.238 Cytochrome c oxidase assembly factor 7 OS=Homo sapiens OX=9606 GN=COA7 PE=1 SV=2 4.65 1540 - 513213 - - - -1.0621 - 3.069 0.532 - 292.6 1 2 0 -0.0019 14 0 0 0 2.39E+06 3.60E+06 - - - 7.4508 0.9934 221125_WJC_METTL3_EV_vs_WT_F10.05593.05593.2 1.22E-11 17/36 S.SYGSGGGSYGSGGGGGGGR.G sp|P04264|K2C1_HUMAN 1 1532.624 999 139087 5593 2 1532.623286 767.3193 "Keratin, type II cytoskeletal 1 OS=Homo sapiens OX=9606 GN=KRT1 PE=1 SV=6" 8.31 1540.4 - 332863 - - - -0.473 - 3.337 0.414 - 718.4 1 1 0 -0.0007 19 0 0 0 3.07E+06 0.00E+00 - - - 5.0613 0.9981 221125_WJC_METTL3_EV_vs_WT_F10.05601.05601.3 0.00441 Sep-40 K.KNHEEEMNALR.G "sp|Q04695|K1C17_HUMAN,sp|P02533|K1C14_HUMAN,tr|K7EPJ9|K7EPJ9_HUMAN,tr|K7ESE1|K7ESE1_HUMAN,tr|F5GWP8|F5GWP8_HUMAN" 5 1369.6408 999 139093 5601 3 1369.638472 457.5542 "Keratin, type I cytoskeletal 17 OS=Homo sapiens OX=9606 GN=KRT17 PE=1 SV=2" 5.5 1541.4 - 3.55E+06 - - - -1.734 - 1.606 0.294 - 119.9 1 2 0 -0.0024 11 0 0 0 1.89E+07 0.00E+00 - - - 3.163 0.9998 221125_WJC_METTL3_EV_vs_WT_F10.05602.05602.4 5.47E-06 16/78 K.VSDEAVKKDSELDK.H "sp|O75688|PPM1B_HUMAN,tr|B8ZZF0|B8ZZF0_HUMAN,tr|A0A3B3IS24|A0A3B3IS24_HUMAN,tr|C9JIR6|C9JIR6_HUMAN" 4 1561.7835 3.42 139094 5602 4 1561.782675 391.4532 Protein phosphatase 1B OS=Homo sapiens OX=9606 GN=PPM1B PE=1 SV=1 4.44 1541.4 - 2.80E+06 - - - -0.5487 - 2.972 0.468 - 196.3 1 2 1 -0.0009 14 0 0 0 1.00E+07 2.92E+06 - - - 3.6957 0.9344 221125_WJC_METTL3_EV_vs_WT_F10.05603.05603.3 0.354 Jul-36 R.DSHTLHEVLR[166.11].K "sp|O75943|RAD17_HUMAN,tr|A0A0G2JNH5|A0A0G2JNH5_HUMAN,tr|A0A0G2JP78|A0A0G2JP78_HUMAN,tr|A0A0G2JPT5|A0A0G2JPT5_HUMAN" 4 1215.6236 0.45 139095 5603 3 1215.622109 406.2151 Cell cycle checkpoint protein RAD17 OS=Homo sapiens OX=9606 GN=RAD17 PE=1 SV=2 5.99 1541.5 - 2.65E+06 - - - -1.1895 - 1.633 0.082 - 65.9 2 2 0 -0.0014 10 0 0 0 1.08E+07 2.40E+07 - - - 0.7467 0.9985 221125_WJC_METTL3_EV_vs_WT_F10.05604.05604.2 0.0036 16/20 K.HKSETDTSLIR.G sp|P40227|TCPZ_HUMAN 1 1285.6626 0.37 139096 5604 2 1285.661277 643.8386 T-complex protein 1 subunit zeta OS=Homo sapiens OX=9606 GN=CCT6A PE=1 SV=3 6.75 1541.6 - 1.34E+06 - - - -1.0516 - 2.461 0.483 - 647.5 1 2 1 -0.0014 11 0 0 0 5.19E+06 1.39E+07 - - - 5.0443 0.9999 221125_WJC_METTL3_EV_vs_WT_F10.05608.05608.3 9.36E-05 13/60 R.GSSPGPR[166.11]PVEGTPASR[166.11].T sp|Q13112|CAF1B_HUMAN 1 1570.7967 2.21 139100 5608 3 1570.798717 524.6062 Chromatin assembly factor 1 subunit B OS=Homo sapiens OX=9606 GN=CHAF1B PE=1 SV=1 9.6 1542 - 933970 - - - 1.3108 - 2.343 0.465 - 205.6 1 2 0 0.0021 16 0 0 0 7.04E+06 3.18E+06 - - - 5.9084 0.9865 221125_WJC_METTL3_EV_vs_WT_F10.05609.05609.3 0.104 Aug-32 K.FK[136.11]YDDAER[166.11]R[166.11].F "sp|P29692|EF1D_HUMAN,tr|E9PI39|E9PI39_HUMAN,tr|E9PMW7|E9PMW7_HUMAN,tr|E9PKK3|E9PKK3_HUMAN,tr|E9PQ49|E9PQ49_HUMAN,tr|A0A087X1X7|A0A087X1X7_HUMAN,tr|E9PL12|E9PL12_HUMAN,tr|E9PK72|E9PK72_HUMAN,tr|H0YCK7|H0YCK7_HUMAN,tr|E9PQZ1|E9PQZ1_HUMAN,tr|E9PK06|E9PK06_HUMAN,tr|E9PIZ1|E9PIZ1_HUMAN,tr|E9PN91|E9PN91_HUMAN,tr|E9PNW6|E9PNW6_HUMAN,tr|E9PPR1|E9PPR1_HUMAN,tr|E9PRY8|E9PRY8_HUMAN,tr|E9PK01|E9PK01_HUMAN,tr|E9PJD0|E9PJD0_HUMAN,tr|E9PL71|E9PL71_HUMAN" 19 1226.6038 1.22 139101 5609 3 1226.602945 409.8752 Elongation factor 1-delta OS=Homo sapiens OX=9606 GN=EEF1D PE=1 SV=5 6.12 1542.1 - 831880 - - - -0.7174 - 1.725 0.214 - 87.1 1 2 1 -0.0009 9 0 0 0 6.59E+06 5.40E+06 - - - 2.5688 0.8999 221125_WJC_METTL3_EV_vs_WT_F10.05610.05610.3 0.00274 Aug-48 T.HTSDEQNHLVVAR.V "sp|Q16576|RBBP7_HUMAN,tr|C9J7L0|C9J7L0_HUMAN,tr|E9PC52|E9PC52_HUMAN" 3 1504.7383 0.67 139102 5610 3 1504.736579 502.5867 Histone-binding protein RBBP7 OS=Homo sapiens OX=9606 GN=RBBP7 PE=1 SV=1 5.99 1542.2 - 726657 - - - -1.1125 - 1.411 0.344 - 60.7 1 1 0 -0.0017 13 0 0 0 2.73E+06 4.08E+06 - - - 3.3083 0.967 221125_WJC_METTL3_EV_vs_WT_F10.05616.05616.3 0.021 Jul-48 R.AFAGATTLNNHIR[166.11].T sp|Q9NQX0|PRDM6_HUMAN 1 1394.7294 0.05 139106 5616 3 1394.73637 465.9171 Putative histone-lysine N-methyltransferase PRDM6 OS=Homo sapiens OX=9606 GN=PRDM6 PE=1 SV=2 9.8 1543 - 6.60E+06 - - - 4.9852 - 1.726 0.25 - 51.1 1 2 0 0.007 13 0 0 0 2.14E+06 4.57E+07 - - - 2.8052 1 221125_WJC_METTL3_EV_vs_WT_F10.05617.05617.3 1.45E-06 17/52 R.QSSSYGPHGYGSGR.S sp|Q86YZ3|HORN_HUMAN 1 1438.6226 192.95 139107 5617 3 1438.622197 480.5481 Hornerin OS=Homo sapiens OX=9606 GN=HRNR PE=1 SV=2 8.6 1543 - 4.02E+06 - - - -0.2488 - 3.101 0.605 - 517.9 1 2 0 -0.0004 14 0 0 0 2.62E+08 1.36E+06 - - - 8.2926 1 221125_WJC_METTL3_EV_vs_WT_F10.05618.05618.2 2.05E-10 16/34 K.NQGGGLSSSGAGEGQGPK[136.11].K sp|P07814|SYEP_HUMAN 1 1594.7427 0.93 139108 5618 2 1594.742881 798.3786 Bifunctional glutamate\proline--tRNA ligase OS=Homo sapiens OX=9606 GN=EPRS1 PE=1 SV=5 6 1543.1 - 2.02E+06 - - - 0.1279 - 3.221 0.682 - 742.3 1 2 0 0.0002 18 0 0 0 2.21E+07 2.37E+07 - - - 6.9539 1 221125_WJC_METTL3_EV_vs_WT_F10.05619.05619.2 4.71E-10 23/34 K.NQGGGLSSSGAGEGQGPK.K sp|P07814|SYEP_HUMAN 1 1586.7285 0.93 139109 5619 2 1586.727899 794.3715 Bifunctional glutamate\proline--tRNA ligase OS=Homo sapiens OX=9606 GN=EPRS1 PE=1 SV=5 6 1543.2 - 1.82E+06 - - - -0.3643 - 3.759 0.75 - 1911.5 1 2 0 -0.0006 18 0 0 0 2.21E+07 2.37E+07 - - - 7.8358 1 221125_WJC_METTL3_EV_vs_WT_F10.05620.05620.3 3.09E-07 17/56 R.LSGK[136.11]PQNAPEGYQNR[166.11].L sp|Q12834|CDC20_HUMAN 1 1675.8397 1.04 139110 5620 3 1675.838308 559.6205 Cell division cycle protein 20 homolog OS=Homo sapiens OX=9606 GN=CDC20 PE=1 SV=2 8.59 1543.2 - 1.57E+06 - - - -0.8318 - 2.852 0.587 - 356.1 1 2 0 -0.0014 15 0 0 0 8.15E+06 7.83E+06 - - - 7.8188 1 221125_WJC_METTL3_EV_vs_WT_F10.05621.05621.3 2.81E-07 14/56 R.LSGKPQNAPEGYQNR.L sp|Q12834|CDC20_HUMAN 1 1657.8172 1.04 139111 5621 3 1657.816202 553.613 Cell division cycle protein 20 homolog OS=Homo sapiens OX=9606 GN=CDC20 PE=1 SV=2 8.59 1543.3 - 1.39E+06 - - - -0.6213 - 2.616 0.51 - 180.7 1 2 0 -0.001 15 0 0 0 8.15E+06 7.83E+06 - - - 6.735 0.9999 221125_WJC_METTL3_EV_vs_WT_F10.05624.05624.2 4.27E-08 18/30 R.QQGTSVAQSGAQAPGR.A "sp|Q9BWE0|REPI1_HUMAN,tr|C9JZE3|C9JZE3_HUMAN,tr|E7EVL6|E7EVL6_HUMAN,tr|C9JYJ8|C9JYJ8_HUMAN" 4 1541.7546 1.01 139114 5624 2 1541.754257 771.8846 Replication initiator 1 OS=Homo sapiens OX=9606 GN=REPIN1 PE=1 SV=1 9.75 1543.6 - 857822 - - - -0.2432 - 2.954 0.537 - 960.1 1 2 0 -0.0004 16 0 0 0 4.32E+06 4.28E+06 - - - 5.6702 1 221125_WJC_METTL3_EV_vs_WT_F10.05625.05625.2 5.52E-10 19/30 R.QQGTSVAQSGAQAPGR[166.11].A "sp|Q9BWE0|REPI1_HUMAN,tr|C9JZE3|C9JZE3_HUMAN,tr|E7EVL6|E7EVL6_HUMAN,tr|C9JYJ8|C9JYJ8_HUMAN" 4 1551.7629 1.01 139115 5625 2 1551.765612 776.8887 Replication initiator 1 OS=Homo sapiens OX=9606 GN=REPIN1 PE=1 SV=1 9.75 1543.8 - 853665 - - - 1.7464 - 3.221 0.587 - 1284.6 1 2 0 0.0027 16 0 0 0 4.32E+06 4.28E+06 - - - 6.2515 0.9999 221125_WJC_METTL3_EV_vs_WT_F10.05639.05639.3 0.000272 19/44 R.SKEEAEALYHSK.Y sp|P35908|K22E_HUMAN 1 1390.6729 95.73 139128 5639 3 1390.673881 464.5649 "Keratin, type II cytoskeletal 2 epidermal OS=Homo sapiens OX=9606 GN=KRT2 PE=1 SV=2" 5.47 1545.3 - 3.99E+07 - - - 0.7349 - 3.238 0.5 - 599.3 1 2 1 0.001 12 0 0 0 3.03E+09 3.17E+07 - - - 7.371 0.9875 221125_WJC_METTL3_EV_vs_WT_F10.05640.05640.3 0.00207 13/44 A.DITDGNSEHLKR.E "sp|Q12907|LMAN2_HUMAN,tr|D6RBV2|D6RBV2_HUMAN,tr|D6RDX1|D6RDX1_HUMAN,tr|D6RBH1|D6RBH1_HUMAN" 4 1383.6743 1.9 139129 5640 3 1383.676765 462.232 Vesicular integral-membrane protein VIP36 OS=Homo sapiens OX=9606 GN=LMAN2 PE=1 SV=1 5.38 1545.3 - 7.23E+06 - - - 1.8133 - 2.539 0.397 - 173 1 1 0 0.0025 12 0 0 0 2.81E+07 1.47E+07 - - - 5.5482 0.9562 221125_WJC_METTL3_EV_vs_WT_F10.05641.05641.2 1.33 12-Aug D.SGHLDLR[166.11].N "sp|Q86U44|MTA70_HUMAN,tr|D6R9M9|D6R9M9_HUMAN,tr|B4E349|B4E349_HUMAN,tr|F5H6D8|F5H6D8_HUMAN,tr|B4DTN4|B4DTN4_HUMAN,tr|D6R9X6|D6R9X6_HUMAN" 6 806.4274 0.13 139130 5641 2 806.426903 404.221 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 6.46 1545.4 - 5.79E+06 - - - -0.6423 - 1.723 0.258 - 314.7 1 1 0 -0.0005 7 0 0 0 4.17E+06 3.18E+07 - - - 2.6703 0.9978 221125_WJC_METTL3_EV_vs_WT_F10.05643.05643.3 6.24E-06 Dec-44 A.DITDGNSEHLK[136.11]R[166.11].E "sp|Q12907|LMAN2_HUMAN,tr|D6RBV2|D6RBV2_HUMAN,tr|D6RDX1|D6RDX1_HUMAN,tr|D6RBH1|D6RBH1_HUMAN" 4 1401.6967 1.9 139132 5643 3 1401.695201 468.2395 Vesicular integral-membrane protein VIP36 OS=Homo sapiens OX=9606 GN=LMAN2 PE=1 SV=1 5.38 1545.5 - 4.34E+06 - - - -1.088 - 2.808 0.506 - 117.9 1 1 0 -0.0015 12 0 0 0 2.81E+07 1.47E+07 - - - 7.0428 1 221125_WJC_METTL3_EV_vs_WT_F10.05646.05646.2 7.48E-08 13/22 W.PDATYGTGSASR.A "sp|Q9Y2W1|TR150_HUMAN,tr|A0A3B3ITZ9|A0A3B3ITZ9_HUMAN" 2 1181.5313 2.87 139135 5646 2 1181.531314 591.7729 Thyroid hormone receptor-associated protein 3 OS=Homo sapiens OX=9606 GN=THRAP3 PE=1 SV=2 6.26 1545.7 - 2.06E+06 - - - 0.0288 - 2.602 0.675 - 721.7 1 1 0 0 12 0 0 0 7.53E+06 2.63E+06 - - - 6.5427 1 221125_WJC_METTL3_EV_vs_WT_F10.05647.05647.3 1.02E-09 14/68 K.NQGGGLSSSGAGEGQGPK[136.11].K sp|P07814|SYEP_HUMAN 1 1594.7427 -1 139136 5647 3 1594.741094 532.5882 Bifunctional glutamate\proline--tRNA ligase OS=Homo sapiens OX=9606 GN=EPRS1 PE=1 SV=5 6 1545.7 - 1.68E+06 - - - -0.9926 - 2.794 0.654 - 252 1 2 0 -0.0016 18 0 0 0 0.00E+00 0.00E+00 - - - 8.3895 1 221125_WJC_METTL3_EV_vs_WT_F10.05648.05648.3 9.32E-09 20/68 K.NQGGGLSSSGAGEGQGPK.K sp|P07814|SYEP_HUMAN 1 1586.7285 1.05 139137 5648 3 1586.727964 529.9168 Bifunctional glutamate\proline--tRNA ligase OS=Homo sapiens OX=9606 GN=EPRS1 PE=1 SV=5 6 1545.8 - 1.63E+06 - - - -0.3233 - 3.104 0.64 - 513.4 1 2 0 -0.0005 18 0 0 0 4.77E+06 4.54E+06 - - - 8.4957 0.9999 221125_WJC_METTL3_EV_vs_WT_F10.05649.05649.2 0.00111 18-Oct R.K[136.11]QDSGHLDLR[166.11].N "sp|Q86U44|MTA70_HUMAN,tr|B4E349|B4E349_HUMAN,tr|F5H6D8|F5H6D8_HUMAN,tr|B4DTN4|B4DTN4_HUMAN" 4 1185.6221 0.001 139138 5649 2 1185.620537 593.8183 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 6.75 1545.9 - 1.56E+06 - - - -1.3225 - 2.235 0.526 - 371.2 1 2 0 -0.0016 10 0 0 0 0.00E+00 7.36E+06 - - - 5.1704 0.9988 221125_WJC_METTL3_EV_vs_WT_F10.05654.05654.2 0.023 18/22 R.SKEEAEALYHSK.Y sp|P35908|K22E_HUMAN 1 1390.6729 204.39 139143 5654 2 1390.671673 696.3437 "Keratin, type II cytoskeletal 2 epidermal OS=Homo sapiens OX=9606 GN=KRT2 PE=1 SV=2" 5.47 1546.4 - 957774 - - - -0.8528 - 3.207 0.439 - 935.5 1 2 1 -0.0012 12 0 0 0 1.18E+08 5.79E+05 - - - 5.3493 0.9999 221125_WJC_METTL3_EV_vs_WT_F10.05655.05655.2 1.96E-06 13/24 K.SSSQTSTSQLPSK[136.11].S sp|Q9NXV6|CARF_HUMAN 1 1344.6612 0.97 139144 5655 2 1344.660995 673.3379 CDKN2A-interacting protein OS=Homo sapiens OX=9606 GN=CDKN2AIP PE=1 SV=3 8.47 1546.5 - 763828 - - - -0.1807 - 2.666 0.414 - 496.9 1 2 0 -0.0002 13 0 0 0 1.06E+07 1.09E+07 - - - 4.6154 0.9998 221125_WJC_METTL3_EV_vs_WT_F10.05658.05658.2 5.06E-08 24-Dec K.SSSQTSTSQLPSK.S sp|Q9NXV6|CARF_HUMAN 1 1336.647 0.97 139146 5658 2 1336.645678 669.3308 CDKN2A-interacting protein OS=Homo sapiens OX=9606 GN=CDKN2AIP PE=1 SV=3 8.47 1546.9 - 2.30E+06 - - - -1.0175 - 2.567 0.418 - 412.7 1 2 0 -0.0014 13 0 0 0 1.06E+07 1.09E+07 - - - 4.5475 1 221125_WJC_METTL3_EV_vs_WT_F10.05659.05659.2 4.80E-07 14/22 W.PDATYGTGSASR[166.11].A "sp|Q9Y2W1|TR150_HUMAN,tr|A0A3B3ITZ9|A0A3B3ITZ9_HUMAN" 2 1191.5395 2.87 139147 5659 2 1191.538821 596.7771 Thyroid hormone receptor-associated protein 3 OS=Homo sapiens OX=9606 GN=THRAP3 PE=1 SV=2 6.26 1547 - 932765 - - - -0.6118 - 2.587 0.616 - 620.8 1 1 0 -0.0007 12 0 0 0 7.53E+06 2.63E+06 - - - 6.0915 1 221125_WJC_METTL3_EV_vs_WT_F10.05660.05660.3 2.87E-05 14/36 R.K[136.11]QDSGHLDLR[166.11].N "sp|Q86U44|MTA70_HUMAN,tr|B4E349|B4E349_HUMAN,tr|F5H6D8|F5H6D8_HUMAN,tr|B4DTN4|B4DTN4_HUMAN" 4 1185.6221 0.02 139148 5660 3 1185.621266 396.2146 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 6.75 1547 - 1.66E+07 - - - -0.7076 - 2.5 0.551 - 256.3 1 2 0 -0.0008 10 0 0 0 4.68E+06 2.22E+08 - - - 7.3588 1 221125_WJC_METTL3_EV_vs_WT_F10.05663.05663.2 1.41E-05 16/26 R.QSSSYGPHGYGSGR.S sp|Q86YZ3|HORN_HUMAN 1 1438.6226 999 139151 5663 2 1438.621126 720.3186 Hornerin OS=Homo sapiens OX=9606 GN=HRNR PE=1 SV=2 8.6 1547.2 - 2.39E+06 - - - -0.9933 - 2.708 0.638 - 856.3 1 2 0 -0.0014 14 0 0 0 1.13E+07 0.00E+00 - - - 6.2528 0.9994 221125_WJC_METTL3_EV_vs_WT_F10.05666.05666.2 2.01E-05 18-Dec K.EEAEALYHSK.Y sp|P35908|K22E_HUMAN 1 1175.5459 999 139154 5666 2 1175.542 588.7802 "Keratin, type II cytoskeletal 2 epidermal OS=Homo sapiens OX=9606 GN=KRT2 PE=1 SV=2" 4.75 1547.5 - 811838 - - - -3.2904 - 2.178 0.514 - 851.2 1 2 0 -0.0039 10 0 0 0 1.00E+07 0.00E+00 - - - 5.009 1 221125_WJC_METTL3_EV_vs_WT_F10.05669.05669.3 3.81E-06 Oct-44 K.HSSTPNSSEFSR[166.11].K sp|Q8N9Q2|SR1IP_HUMAN 1 1344.5934 0.44 139157 5669 3 1344.592724 449.2051 Protein SREK1IP1 OS=Homo sapiens OX=9606 GN=SREK1IP1 PE=1 SV=1 6.75 1547.8 - 622680 - - - -0.4856 - 2.116 0.475 - 133.5 1 2 0 -0.0007 12 0 0 0 2.86E+06 6.49E+06 - - - 5.9132 0.9998 221125_WJC_METTL3_EV_vs_WT_F10.05684.05684.3 0.0017 Dec-36 K.EEAEALYHSK.Y sp|P35908|K22E_HUMAN 1 1175.5459 9.6 139170 5684 3 1175.544307 392.8559 "Keratin, type II cytoskeletal 2 epidermal OS=Homo sapiens OX=9606 GN=KRT2 PE=1 SV=2" 4.75 1549.5 - 983640 - - - -1.3279 - 1.942 0.362 - 219.7 1 2 0 -0.0016 10 0 0 0 3.98E+06 4.15E+05 - - - 4.5139 0.9998 221125_WJC_METTL3_EV_vs_WT_F10.05685.05685.2 3.68E-05 22-Nov K.DSYVGDEAQSKR.G "sp|P63261|ACTG_HUMAN,sp|P68133|ACTS_HUMAN,sp|P62736|ACTA_HUMAN,sp|P68032|ACTC_HUMAN,sp|P60709|ACTB_HUMAN,sp|P63267|ACTH_HUMAN,tr|A0A804GS07|A0A804GS07_HUMAN,tr|I3L3I0|I3L3I0_HUMAN,tr|G5E9R0|G5E9R0_HUMAN,tr|E7EVS6|E7EVS6_HUMAN,tr|A0A6Q8PFE4|A0A6Q8PFE4_HUMAN,tr|B8ZZJ2|B8ZZJ2_HUMAN,tr|J3KT65|J3KT65_HUMAN,tr|I3L3R2|I3L3R2_HUMAN,tr|K7EM38|K7EM38_HUMAN,tr|F6QUT6|F6QUT6_HUMAN,tr|C9JTX5|C9JTX5_HUMAN,tr|A0A6Q8PH58|A0A6Q8PH58_HUMAN,tr|F6UVQ4|F6UVQ4_HUMAN,tr|F8WB63|F8WB63_HUMAN,tr|I3L1U9|I3L1U9_HUMAN,tr|A0A804HKV3|A0A804HKV3_HUMAN,tr|A0A2R8Y793|A0A2R8Y793_HUMAN,tr|I3L4N8|I3L4N8_HUMAN,tr|C9JUM1|C9JUM1_HUMAN,tr|C9JZR7|C9JZR7_HUMAN,tr|C9JFL5|C9JFL5_HUMAN,tr|A0A2R8YGF8|A0A2R8YGF8_HUMAN,tr|A6NL76|A6NL76_HUMAN" 29 1353.6161 0.85 139171 5685 2 1353.614863 677.8153 "Actin, cytoplasmic 2 OS=Homo sapiens OX=9606 GN=ACTG1 PE=1 SV=1" 4.56 1549.6 - 841921 - - - -0.8939 - 1.783 0.544 - 256.6 1 2 0 -0.0012 12 0 0 0 4.57E+06 5.36E+06 - - - 4.5802 0.9999 221125_WJC_METTL3_EV_vs_WT_F10.05691.05691.3 0.000415 Nov-64 R.LGTNQENQQPNQQPPGK.K sp|O95235|KI20A_HUMAN 1 1876.9028 1.92 139177 5691 3 1876.901168 626.6415 Kinesin-like protein KIF20A OS=Homo sapiens OX=9606 GN=KIF20A PE=1 SV=1 6 1550.3 - 630104 - - - -0.8445 - 1.931 0.439 - 96.3 1 2 0 -0.0016 17 0 0 0 3.04E+06 1.58E+06 - - - 5.0964 1 221125_WJC_METTL3_EV_vs_WT_F10.05692.05692.2 8.12E-07 14/28 K.GGSISGGGYGSGGGK.H sp|P35908|K22E_HUMAN 1 1196.5422 51.2 139178 5692 2 1196.542161 599.2784 "Keratin, type II cytoskeletal 2 epidermal OS=Homo sapiens OX=9606 GN=KRT2 PE=1 SV=2" 8.59 1550.5 - 588501 - - - -0.015 - 2.614 0.649 - 520.2 1 2 0 0 15 0 0 0 4.98E+06 9.74E+04 - - - 6.1969 0.9993 221125_WJC_METTL3_EV_vs_WT_F10.05694.05694.2 0.000684 28-Jul R.QNPQSPPQDSSVTSK[136.11].R "sp|Q9UBN7|HDAC6_HUMAN,tr|Q9BRX7|Q9BRX7_HUMAN,tr|A6NDI8|A6NDI8_HUMAN,tr|A0A2R8YCS4|A0A2R8YCS4_HUMAN,tr|E7EP63|E7EP63_HUMAN,tr|C9J172|C9J172_HUMAN,tr|E7ER52|E7ER52_HUMAN,tr|C9JEF4|C9JEF4_HUMAN" 8 1606.7678 1.92 139180 5694 2 1606.764058 804.3912 Histone deacetylase 6 OS=Homo sapiens OX=9606 GN=HDAC6 PE=1 SV=2 5.84 1550.7 - 441435 - - - -2.3469 - 1.551 0.486 - 100.1 1 2 0 -0.0038 15 0 0 0 7.43E+06 3.87E+06 - - - 3.7085 1 221125_WJC_METTL3_EV_vs_WT_F10.05699.05699.3 2.55E-07 20/68 R.VAAASGHC[160.03]GAFSGSDSSR[166.11].T "sp|Q9NZB2|F120A_HUMAN,tr|A0A494C0Y9|A0A494C0Y9_HUMAN" 2 1732.7463 0.92 139183 5699 3 1732.739745 578.5894 Constitutive coactivator of PPAR-gamma-like protein 1 OS=Homo sapiens OX=9606 GN=FAM120A PE=1 SV=2 6.71 1551.4 - 1.99E+06 - - - -3.7634 - 3.84 0.685 - 626.9 1 2 0 -0.0065 18 0 0 0 3.54E+07 3.84E+07 - - - 9.5256 1 221125_WJC_METTL3_EV_vs_WT_F10.05700.05700.3 2.84E-12 19/68 R.VAAASGHC[160.03]GAFSGSDSSR.T "sp|Q9NZB2|F120A_HUMAN,tr|A0A494C0Y9|A0A494C0Y9_HUMAN" 2 1722.738 0.91 139184 5700 3 1722.735547 575.2533 Constitutive coactivator of PPAR-gamma-like protein 1 OS=Homo sapiens OX=9606 GN=FAM120A PE=1 SV=2 6.71 1551.4 - 1.75E+06 - - - -1.4216 - 3.709 0.731 - 539.9 1 2 0 -0.0024 18 0 0 0 3.51E+07 3.84E+07 - - - 9.9532 1 221125_WJC_METTL3_EV_vs_WT_F10.05701.05701.3 0.000133 14/48 K.FQRPGDPQSAQDK.A "sp|Q15637|SF01_HUMAN,tr|H7C561|H7C561_HUMAN,tr|A0A7P0T9U7|A0A7P0T9U7_HUMAN" 3 1472.7008 1.12 139185 5701 3 1472.699367 491.9075 Splicing factor 1 OS=Homo sapiens OX=9606 GN=SF1 PE=1 SV=4 5.96 1551.5 - 1.53E+06 - - - -0.9764 - 2.654 0.466 - 240.2 1 2 0 -0.0014 13 0 0 0 1.83E+07 1.63E+07 - - - 6.3814 1 221125_WJC_METTL3_EV_vs_WT_F10.05702.05702.2 1.61E-11 17/32 K.SPGSTPTTPTSSQAPQK.L "sp|P35658|NU214_HUMAN,tr|A0A494C1F2|A0A494C1F2_HUMAN" 2 1670.8111 2.09 139186 5702 2 1670.80907 836.4128 Nuclear pore complex protein Nup214 OS=Homo sapiens OX=9606 GN=NUP214 PE=1 SV=2 8.47 1551.6 - 1.34E+06 - - - -1.2413 - 3.316 0.692 - 709.4 1 2 0 -0.0021 17 0 0 0 4.51E+07 2.16E+07 - - - 7.0987 1 221125_WJC_METTL3_EV_vs_WT_F10.05706.05706.2 6.11E-12 17/32 K.SPGSTPTTPTSSQAPQK[136.11].L "sp|P35658|NU214_HUMAN,tr|A0A494C1F2|A0A494C1F2_HUMAN" 2 1678.8253 2.09 139190 5706 2 1678.823046 840.4199 Nuclear pore complex protein Nup214 OS=Homo sapiens OX=9606 GN=NUP214 PE=1 SV=2 8.47 1552.1 - 821186 - - - -1.3688 - 3.461 0.666 - 820.9 1 2 0 -0.0023 17 0 0 0 4.51E+07 2.16E+07 - - - 7.0118 1 221125_WJC_METTL3_EV_vs_WT_F10.05707.05707.3 2.58E-07 17/64 K.SPGSTPTTPTSSQAPQK.L "sp|P35658|NU214_HUMAN,tr|A0A494C1F2|A0A494C1F2_HUMAN" 2 1670.8111 2.41 139191 5707 3 1670.813475 557.9443 Nuclear pore complex protein Nup214 OS=Homo sapiens OX=9606 GN=NUP214 PE=1 SV=2 8.47 1552.2 - 805139 - - - 1.3951 - 3.111 0.525 - 389.5 1 2 0 0.0023 17 0 0 0 2.41E+07 9.98E+06 - - - 7.2598 0.9998 221125_WJC_METTL3_EV_vs_WT_F10.05708.05708.2 4.66E-06 22-Aug K.DSYVGDEAQSK[136.11]R[166.11].G "sp|P63261|ACTG_HUMAN,sp|P68133|ACTS_HUMAN,sp|P62736|ACTA_HUMAN,sp|P68032|ACTC_HUMAN,sp|P60709|ACTB_HUMAN,sp|P63267|ACTH_HUMAN,tr|A0A804GS07|A0A804GS07_HUMAN,tr|I3L3I0|I3L3I0_HUMAN,tr|G5E9R0|G5E9R0_HUMAN,tr|E7EVS6|E7EVS6_HUMAN,tr|A0A6Q8PFE4|A0A6Q8PFE4_HUMAN,tr|B8ZZJ2|B8ZZJ2_HUMAN,tr|J3KT65|J3KT65_HUMAN,tr|I3L3R2|I3L3R2_HUMAN,tr|K7EM38|K7EM38_HUMAN,tr|F6QUT6|F6QUT6_HUMAN,tr|C9JTX5|C9JTX5_HUMAN,tr|A0A6Q8PH58|A0A6Q8PH58_HUMAN,tr|F6UVQ4|F6UVQ4_HUMAN,tr|F8WB63|F8WB63_HUMAN,tr|I3L1U9|I3L1U9_HUMAN,tr|A0A804HKV3|A0A804HKV3_HUMAN,tr|A0A2R8Y793|A0A2R8Y793_HUMAN,tr|I3L4N8|I3L4N8_HUMAN,tr|C9JUM1|C9JUM1_HUMAN,tr|C9JZR7|C9JZR7_HUMAN,tr|C9JFL5|C9JFL5_HUMAN,tr|A0A2R8YGF8|A0A2R8YGF8_HUMAN,tr|A6NL76|A6NL76_HUMAN" 29 1371.6385 0.85 139192 5708 2 1371.636641 686.8265 "Actin, cytoplasmic 2 OS=Homo sapiens OX=9606 GN=ACTG1 PE=1 SV=1" 4.56 1552.3 - 608858 - - - -1.3867 - 1.575 0.608 - 143.5 1 2 0 -0.0019 12 0 0 0 4.57E+06 5.36E+06 - - - 4.7263 1 221125_WJC_METTL3_EV_vs_WT_F10.05711.05711.3 0.00297 15/48 K.FQR[166.11]PGDPQSAQDK[136.11].A "sp|Q15637|SF01_HUMAN,tr|H7C561|H7C561_HUMAN,tr|A0A7P0T9U7|A0A7P0T9U7_HUMAN" 3 1490.7233 1.12 139193 5711 3 1490.723526 497.915 Splicing factor 1 OS=Homo sapiens OX=9606 GN=SF1 PE=1 SV=4 5.96 1552.8 - 1.35E+06 - - - 0.1684 - 2.71 0.434 - 218.8 1 2 0 0.0003 13 0 0 0 1.83E+07 1.63E+07 - - - 6.0816 0.9995 221125_WJC_METTL3_EV_vs_WT_F10.05713.05713.3 0.000594 Oct-40 R.ATEK[136.11]DK[136.11]VEIYK[136.11].S "sp|Q9Y3B2|EXOS1_HUMAN,tr|B1AMU3|B1AMU3_HUMAN" 2 1346.7508 0.87 139195 5713 3 1346.751342 449.9242 Exosome complex component CSL4 OS=Homo sapiens OX=9606 GN=EXOSC1 PE=1 SV=1 6.22 1552.9 - 1.05E+06 - - - 0.4158 - 2.052 0.405 - 134.4 1 2 2 0.0006 11 0 0 0 6.71E+06 7.72E+06 - - - 5.0972 0.9749 221125_WJC_METTL3_EV_vs_WT_F10.05714.05714.3 0.0383 Jul-40 R.ATEKDKVEIYK.S "sp|Q9Y3B2|EXOS1_HUMAN,tr|B1AMU3|B1AMU3_HUMAN" 2 1322.7082 0.87 139196 5714 3 1322.709099 441.91 Exosome complex component CSL4 OS=Homo sapiens OX=9606 GN=EXOSC1 PE=1 SV=1 6.22 1553 - 940484 - - - 0.6933 - 1.616 0.203 - 52.9 1 2 2 0.0009 11 0 0 0 6.71E+06 7.72E+06 - - - 2.1665 1 221125_WJC_METTL3_EV_vs_WT_F10.05715.05715.3 2.14E-06 13/36 R.KPEDWDERPK.L "sp|P27824|CALX_HUMAN,tr|A0A7P0T937|A0A7P0T937_HUMAN,tr|A0A7P0T840|A0A7P0T840_HUMAN,tr|A0A7P0TB65|A0A7P0TB65_HUMAN,tr|A0A7P0TAE9|A0A7P0TAE9_HUMAN,tr|D6RGY2|D6RGY2_HUMAN,tr|A0A7P0T8G1|A0A7P0T8G1_HUMAN,tr|A0A7P0Z4D6|A0A7P0Z4D6_HUMAN,tr|A0A7P0Z484|A0A7P0Z484_HUMAN,tr|A0A7P0TAR9|A0A7P0TAR9_HUMAN,tr|A0A7P0T9L0|A0A7P0T9L0_HUMAN" 11 1298.6255 1.13 139197 5715 3 1298.62667 433.8824 Calnexin OS=Homo sapiens OX=9606 GN=CANX PE=1 SV=2 4.78 1553.1 - 787027 - - - 0.8894 - 2.607 0.451 - 353.7 1 2 0 0.0012 10 0 0 0 2.15E+07 1.91E+07 - - - 6.3662 0.9996 221125_WJC_METTL3_EV_vs_WT_F10.05716.05716.3 0.000172 15/48 R.TKTPGPGAQSALR.A "sp|P62263|RS14_HUMAN,tr|A0A2R8Y811|A0A2R8Y811_HUMAN,tr|E5RH77|E5RH77_HUMAN" 3 1282.6993 1.4 139198 5716 3 1282.700579 428.5737 40S ribosomal protein S14 OS=Homo sapiens OX=9606 GN=RPS14 PE=1 SV=3 11 1553.2 - 590257 - - - 0.9589 - 2.804 0.377 - 338 1 2 1 0.0012 13 0 0 0 7.65E+06 5.46E+06 - - - 5.5383 0.9999 221125_WJC_METTL3_EV_vs_WT_F10.05721.05721.2 3.03E-06 Sep-34 R.VAAASGHC[160.03]GAFSGSDSSR[166.11].T "sp|Q9NZB2|F120A_HUMAN,tr|A0A494C0Y9|A0A494C0Y9_HUMAN" 2 1732.7463 0.86 139203 5721 2 1732.747831 867.3804 Constitutive coactivator of PPAR-gamma-like protein 1 OS=Homo sapiens OX=9606 GN=FAM120A PE=1 SV=2 6.71 1553.9 - 152623 - - - 0.9032 - 2.048 0.651 - 151.6 1 2 0 0.0016 18 0 0 0 9.38E+05 1.09E+06 - - - 5.6112 0.9999 221125_WJC_METTL3_EV_vs_WT_F10.05724.05724.3 8.98E-06 13/36 R.K[136.11]PEDWDER[166.11]PK[136.11].L "sp|P27824|CALX_HUMAN,tr|A0A7P0T937|A0A7P0T937_HUMAN,tr|A0A7P0T840|A0A7P0T840_HUMAN,tr|A0A7P0TB65|A0A7P0TB65_HUMAN,tr|A0A7P0TAE9|A0A7P0TAE9_HUMAN,tr|D6RGY2|D6RGY2_HUMAN,tr|A0A7P0T8G1|A0A7P0T8G1_HUMAN,tr|A0A7P0Z4D6|A0A7P0Z4D6_HUMAN,tr|A0A7P0Z484|A0A7P0Z484_HUMAN,tr|A0A7P0TAR9|A0A7P0TAR9_HUMAN,tr|A0A7P0T9L0|A0A7P0T9L0_HUMAN" 11 1324.6622 1.13 139204 5724 3 1324.663081 442.5613 Calnexin OS=Homo sapiens OX=9606 GN=CANX PE=1 SV=2 4.78 1554.3 - 1.32E+06 - - - 0.6764 - 2.569 0.323 - 279 1 2 0 0.0009 10 0 0 0 2.15E+07 1.91E+07 - - - 4.8964 0.9958 221125_WJC_METTL3_EV_vs_WT_F10.05737.05737.3 0.00362 Dec-48 R.NKQTYSTEPNNLK.A "sp|P46779|RL28_HUMAN,tr|H0YMF4|H0YMF4_HUMAN,tr|H0YLP6|H0YLP6_HUMAN,tr|H0YKD8|H0YKD8_HUMAN" 4 1535.758 0.49 139215 5737 3 1535.765091 512.9266 60S ribosomal protein L28 OS=Homo sapiens OX=9606 GN=RPL28 PE=1 SV=3 8.5 1555.9 - 1.52E+06 - - - 4.6264 - 2.396 0.414 - 167 1 2 1 0.0071 13 0 0 0 1.42E+07 2.91E+07 - - - 5.5228 1 221125_WJC_METTL3_EV_vs_WT_F10.05738.05738.3 1.58E-07 14/64 K.SPGSTPTTPTSSQAPQK[136.11].L "sp|P35658|NU214_HUMAN,tr|A0A494C1F2|A0A494C1F2_HUMAN" 2 1678.8253 2.41 139216 5738 3 1678.82424 560.6157 Nuclear pore complex protein Nup214 OS=Homo sapiens OX=9606 GN=NUP214 PE=1 SV=2 8.47 1556 - 1.29E+06 - - - -0.6576 - 2.811 0.523 - 175 1 2 0 -0.0011 17 0 0 0 2.41E+07 9.98E+06 - - - 6.9817 0.9065 221125_WJC_METTL3_EV_vs_WT_F10.05739.05739.2 1.39 22-Jun R.RYPSSISSSPQK.D "sp|Q14157|UBP2L_HUMAN,tr|F8W726|F8W726_HUMAN" 2 1335.6783 2.62 139217 5739 2 1335.681429 668.8464 Ubiquitin-associated protein 2-like OS=Homo sapiens OX=9606 GN=UBAP2L PE=1 SV=2 9.99 1556.1 - 123913 - - - 2.3584 - 1.109 0.068 - 67.7 1 2 0 0.0032 12 0 0 0 1.82E+06 6.96E+05 - - - -0.1855 0.8776 221125_WJC_METTL3_EV_vs_WT_F10.05740.05740.3 0.0156 Jul-80 W.VSPSETHPVSAQPGAGTGSAK[136.11].H sp|Q6WKZ4|RFIP1_HUMAN 1 1971.9741 2.81 139218 5740 3 1971.978783 658.332 Rab11 family-interacting protein 1 OS=Homo sapiens OX=9606 GN=RAB11FIP1 PE=1 SV=3 6.72 1556.2 - 102265 - - - 2.358 - 1.643 0.362 - 32.1 1 1 0 0.0046 21 0 0 0 2.04E+06 7.26E+05 - - - 3.765 0.9917 221125_WJC_METTL3_EV_vs_WT_F10.05743.05743.3 1.51E-06 Dec-80 W.VSPSETHPVSAQPGAGTGSAK.H sp|Q6WKZ4|RFIP1_HUMAN 1 1963.9599 2.81 139219 5743 3 1963.963347 655.6606 Rab11 family-interacting protein 1 OS=Homo sapiens OX=9606 GN=RAB11FIP1 PE=1 SV=3 6.72 1556.6 - 219969 - - - 1.7383 - 2.491 0.468 - 90.6 1 1 0 0.0034 21 0 0 0 2.04E+06 7.26E+05 - - - 5.9449 0.9937 221125_WJC_METTL3_EV_vs_WT_F10.05745.05745.3 1.22E-05 20/64 L.VSGLNSSASEPAK[136.11]EPAK[136.11].K "sp|Q86U44|MTA70_HUMAN,tr|F5H6D8|F5H6D8_HUMAN,tr|H0YFV6|H0YFV6_HUMAN,tr|B4DTN4|B4DTN4_HUMAN" 4 1686.8759 0 139221 5745 3 1686.877415 563.2993 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 6.11 1556.9 - 893346 - - - 0.8809 - 3.757 0.533 - 600.1 1 1 1 0.0015 17 0 0 0 1.04E+05 8.60E+07 - - - 7.8259 0.9992 221125_WJC_METTL3_EV_vs_WT_F10.05746.05746.3 0.00412 13/48 K.SNSQVPQQSHFTK[136.11].T sp|Q9UNY4|TTF2_HUMAN 1 1494.7307 0.74 139222 5746 3 1494.732884 499.2508 Transcription termination factor 2 OS=Homo sapiens OX=9606 GN=TTF2 PE=1 SV=2 8.49 1557 - 579430 - - - 1.4912 - 2.121 0.285 - 282.8 1 2 0 0.0022 13 0 0 0 3.30E+06 4.44E+06 - - - 3.7554 0.9979 221125_WJC_METTL3_EV_vs_WT_F10.05747.05747.3 0.00168 Oct-56 K.TPK[136.11]PGYPSSEEPSSK[136.11].E "sp|Q96PV7|F193B_HUMAN,tr|H0YCX2|H0YCX2_HUMAN" 2 1605.7857 0.44 139223 5747 3 1605.778923 536.2692 Protein FAM193B OS=Homo sapiens OX=9606 GN=FAM193B PE=1 SV=3 5.81 1557.1 - 240313 - - - -4.231 - 1.763 0.399 - 86.7 1 2 0 -0.0068 15 0 0 0 1.88E+06 4.32E+06 - - - 4.4661 1 221125_WJC_METTL3_EV_vs_WT_F10.05749.05749.2 1.33E-10 16/30 R.APSSSSLNSATSSQSK[136.11].K "sp|Q5F1R6|DJC21_HUMAN,tr|A0A2R8Y4Q0|A0A2R8Y4Q0_HUMAN,tr|A0A2R8Y534|A0A2R8Y534_HUMAN" 3 1545.7362 0.86 139225 5749 2 1545.738378 773.8754 DnaJ homolog subfamily C member 21 OS=Homo sapiens OX=9606 GN=DNAJC21 PE=1 SV=2 8.8 1557.4 - 208013 - - - 1.4129 - 3.501 0.739 - 1054.3 1 2 0 0.0022 16 0 0 0 6.11E+06 7.14E+06 - - - 7.5792 0.9997 221125_WJC_METTL3_EV_vs_WT_F10.05750.05750.2 2.69E-06 28-Oct K.SSPSTGSLDSGNESK.E "sp|Q15057|ACAP2_HUMAN,tr|A0A087X1H5|A0A087X1H5_HUMAN,tr|A0A0U1RQT1|A0A0U1RQT1_HUMAN" 3 1451.6376 2.06 139226 5750 2 1451.640999 726.8261 "Arf-GAP with coiled-coil, ANK repeat and PH domain-containing protein 2 OS=Homo sapiens OX=9606 GN=ACAP2 PE=1 SV=3" 4.37 1557.5 - 129638 - - - 2.3442 - 2.15 0.542 - 282.4 1 2 0 0.0034 15 0 0 0 1.36E+06 6.58E+05 - - - 4.9251 1 221125_WJC_METTL3_EV_vs_WT_F10.05758.05758.2 1.21E-11 18/30 R.APSSSSLNSATSSQSK.K "sp|Q5F1R6|DJC21_HUMAN,tr|A0A2R8Y4Q0|A0A2R8Y4Q0_HUMAN,tr|A0A2R8Y534|A0A2R8Y534_HUMAN" 3 1537.722 0.84 139232 5758 2 1537.722236 769.8683 DnaJ homolog subfamily C member 21 OS=Homo sapiens OX=9606 GN=DNAJC21 PE=1 SV=2 8.8 1558.6 - 608377 - - - 0.1574 - 3.741 0.758 - 1380.8 1 2 0 0.0002 16 0 0 0 6.01E+06 7.14E+06 - - - 7.8832 0.9999 221125_WJC_METTL3_EV_vs_WT_F10.05763.05763.2 1.23E-06 24-Nov K.EQTFSGGTSQDTK.A "sp|Q9Y2W1|TR150_HUMAN,tr|A0A3B3ITZ9|A0A3B3ITZ9_HUMAN" 2 1384.6107 2.59 139237 5763 2 1384.611995 693.3126 Thyroid hormone receptor-associated protein 3 OS=Homo sapiens OX=9606 GN=THRAP3 PE=1 SV=2 4.37 1559.2 - 411558 - - - 0.9692 - 2.348 0.603 - 383.2 1 2 0 0.0013 13 0 0 0 2.78E+07 1.07E+07 - - - 5.685 0.9999 221125_WJC_METTL3_EV_vs_WT_F10.05768.05768.2 9.05E-08 13/24 K.EQTFSGGTSQDTK[136.11].A "sp|Q9Y2W1|TR150_HUMAN,tr|A0A3B3ITZ9|A0A3B3ITZ9_HUMAN" 2 1392.6249 2.59 139242 5768 2 1392.623724 697.3197 Thyroid hormone receptor-associated protein 3 OS=Homo sapiens OX=9606 GN=THRAP3 PE=1 SV=2 4.37 1559.8 - 185116 - - - -0.8107 - 2.425 0.595 - 705.1 1 2 0 -0.0011 13 0 0 0 2.78E+07 1.07E+07 - - - 5.7088 0.9998 221125_WJC_METTL3_EV_vs_WT_F10.05769.05769.3 4.28E-05 16/52 K.VETQTEELK[136.11]QNESR[166.11].T "sp|Q6KC79|NIPBL_HUMAN,tr|A0A590UJS4|A0A590UJS4_HUMAN" 2 1707.8394 1.12 139243 5769 3 1707.839678 570.2871 Nipped-B-like protein OS=Homo sapiens OX=9606 GN=NIPBL PE=1 SV=2 4.49 1559.9 - 184552 - - - 0.147 - 2.222 0.472 - 247.2 1 2 1 0.0003 14 0 0 0 3.99E+06 3.58E+06 - - - 5.9241 0.9968 221125_WJC_METTL3_EV_vs_WT_F10.05773.05773.3 0.0383 Sep-52 R.DKATTSGSNSISVR.A sp|Q86XL3|ANKL2_HUMAN 1 1421.711 1.64 139246 5773 3 1421.71393 474.911 Ankyrin repeat and LEM domain-containing protein 2 OS=Homo sapiens OX=9606 GN=ANKLE2 PE=1 SV=4 8.75 1560.5 - 1.51E+06 - - - 2.0356 - 2.202 0.31 - 115.9 1 2 1 0.0029 14 0 0 0 4.41E+06 2.69E+06 - - - 4.0932 0.8078 221125_WJC_METTL3_EV_vs_WT_F10.05787.05787.2 0.101 26-May R.DKATTSGSNSISVR.A sp|Q86XL3|ANKL2_HUMAN 1 1421.711 -1 139260 5787 2 1421.707083 711.8628 Ankyrin repeat and LEM domain-containing protein 2 OS=Homo sapiens OX=9606 GN=ANKLE2 PE=1 SV=4 8.75 1562.1 - 122037 - - - -2.7805 - 0.966 0.281 - 57.4 1 2 1 -0.004 14 0 0 0 0.00E+00 0.00E+00 - - - 1.0284 0.9997 221125_WJC_METTL3_EV_vs_WT_F10.05798.05798.3 0.112 Jun-44 R.DYSDHPSGGSYR.D "sp|Q96E39|RMXL1_HUMAN,sp|P38159|RBMX_HUMAN,tr|H3BUY5|H3BUY5_HUMAN,tr|H3BT71|H3BT71_HUMAN,tr|H0Y6E7|H0Y6E7_HUMAN" 5 1339.5429 1.54 139269 5798 3 1339.541986 447.5216 "RNA binding motif protein, X-linked-like-1 OS=Homo sapiens OX=9606 GN=RBMXL1 PE=1 SV=1" 5.21 1563.5 - 386669 - - - -0.6883 - 1.331 0.44 - 39.3 1 2 0 -0.0009 12 0 0 0 7.78E+06 5.05E+06 - - - 4.2379 1 221125_WJC_METTL3_EV_vs_WT_F10.05800.05800.2 3.31E-05 13/36 R.GAQDVAGGSNPGAHNPSAN.L "sp|O14654|IRS4_HUMAN,tr|A0A804CF45|A0A804CF45_HUMAN" 2 1719.7561 - 139271 5800 2 1719.756206 860.8853 Insulin receptor substrate 4 OS=Homo sapiens OX=9606 GN=IRS4 PE=1 SV=1 5.08 1563.7 - 346607 - - - 0.0686 - 2.87 0.633 - 366 1 1 0 0.0001 19 0 0 0 - - - - - 6.3084 0.9992 221125_WJC_METTL3_EV_vs_WT_F10.05803.05803.3 0.000753 Jul-44 R.DYSDHPSGGSYR[166.11].D "sp|Q96E39|RMXL1_HUMAN,sp|P38159|RBMX_HUMAN,tr|H3BUY5|H3BUY5_HUMAN,tr|H3BT71|H3BT71_HUMAN,tr|H0Y6E7|H0Y6E7_HUMAN" 5 1349.5512 1.53 139274 5803 3 1349.550158 450.8577 "RNA binding motif protein, X-linked-like-1 OS=Homo sapiens OX=9606 GN=RBMXL1 PE=1 SV=1" 5.21 1564.1 - 245862 - - - -0.7558 - 1.519 0.337 - 57.5 1 2 0 -0.001 12 0 0 0 7.76E+06 5.07E+06 - - - 3.4557 0.9986 221125_WJC_METTL3_EV_vs_WT_F10.05811.05811.2 0.0438 26-Apr K.DLESC[160.03]SDDDNQGSK.S "sp|Q5T3I0|GPTC4_HUMAN,tr|F8W895|F8W895_HUMAN,tr|A0A0A0MRK1|A0A0A0MRK1_HUMAN,tr|E9PAV9|E9PAV9_HUMAN" 4 1568.5897 12.75 139280 5811 2 1568.590809 785.3021 G patch domain-containing protein 4 OS=Homo sapiens OX=9606 GN=GPATCH4 PE=1 SV=2 3.71 1565.2 - 80980.7 - - - 0.7325 - 1.045 0.415 - 32.7 1 2 0 0.0011 14 0 0 0 4.99E+05 3.91E+04 - - - 2.2163 1 221125_WJC_METTL3_EV_vs_WT_F10.05812.05812.2 5.75E-08 26-Nov K.QTFC[160.03]SSQTTSNTSR[166.11].Y "sp|Q9NVU0|RPC5_HUMAN,tr|H3BM46|H3BM46_HUMAN,tr|H3BMR4|H3BMR4_HUMAN,tr|H3BRY1|H3BRY1_HUMAN,tr|A0A0C4DH01|A0A0C4DH01_HUMAN" 5 1613.6979 0.94 139281 5812 2 1613.69836 807.8562 DNA-directed RNA polymerase III subunit RPC5 OS=Homo sapiens OX=9606 GN=POLR3E PE=1 SV=1 8.25 1565.3 - 63735.2 - - - 0.2733 - 2.196 0.64 - 425.3 1 2 0 0.0004 14 0 0 0 3.46E+06 3.67E+06 - - - 5.7419 0.9963 221125_WJC_METTL3_EV_vs_WT_F10.05815.05815.3 0.0619 Jul-44 R.HTPVC[160.03]SFNSQNK.Y sp|O60318|GANP_HUMAN 1 1417.6408 2.14 139282 5815 3 1417.640876 473.5542 Germinal-center associated nuclear protein OS=Homo sapiens OX=9606 GN=MCM3AP PE=1 SV=2 8.23 1565.8 - 257503 - - - 0.0198 - 1.349 0.274 - 58.7 1 2 0 0 12 0 0 0 5.16E+06 2.42E+06 - - - 2.4246 0.9997 221125_WJC_METTL3_EV_vs_WT_F10.05818.05818.2 0.0018 26-Jul K.QTFC[160.03]SSQTTSNTSR.Y "sp|Q9NVU0|RPC5_HUMAN,tr|H3BM46|H3BM46_HUMAN,tr|H3BMR4|H3BMR4_HUMAN,tr|H3BRY1|H3BRY1_HUMAN,tr|A0A0C4DH01|A0A0C4DH01_HUMAN" 5 1603.6896 0.94 139285 5818 2 1603.688395 802.8521 DNA-directed RNA polymerase III subunit RPC5 OS=Homo sapiens OX=9606 GN=POLR3E PE=1 SV=1 8.25 1566.1 - 98952 - - - -0.7819 - 1.718 0.473 - 110.2 1 2 0 -0.0013 14 0 0 0 3.46E+06 3.67E+06 - - - 3.8922 0.9984 221125_WJC_METTL3_EV_vs_WT_F10.05833.05833.3 0.00724 Jul-48 R.KGTDDSMTLQSQK.F "sp|O00422|SAP18_HUMAN,tr|H7BZW6|H7BZW6_HUMAN" 2 1437.677 1.33 139296 5833 3 1437.678986 480.2329 Histone deacetylase complex subunit SAP18 OS=Homo sapiens OX=9606 GN=SAP18 PE=1 SV=1 5.96 1568.2 - 85680.1 - - - 1.4106 - 1.548 0.312 - 57.5 1 2 0 0.002 13 0 0 0 2.56E+08 1.92E+08 - - - 3.2027 0.9999 221125_WJC_METTL3_EV_vs_WT_F10.05841.05841.3 1.27E-07 Nov-48 R.K[136.11]GTDDSMTLQSQK[136.11].F "sp|O00422|SAP18_HUMAN,tr|H7BZW6|H7BZW6_HUMAN" 2 1453.7054 1.33 139302 5841 3 1453.709822 485.5757 Histone deacetylase complex subunit SAP18 OS=Homo sapiens OX=9606 GN=SAP18 PE=1 SV=1 5.96 1569.2 - 198205 - - - 3.0708 - 2.465 0.602 - 203.2 1 2 0 0.0045 13 0 0 0 2.56E+08 1.92E+08 - - - 7.6966 0.851 221125_WJC_METTL3_EV_vs_WT_F10.05857.05857.3 0.588 May-40 R.HMNGYGSHTFK.L sp|P04040|CATA_HUMAN 1 1277.5611 2.78 139311 5857 3 1277.563508 426.861 Catalase OS=Homo sapiens OX=9606 GN=CAT PE=1 SV=3 8.61 1571.5 - 150478 - - - 1.8527 - 0.909 0.201 - 23 1 2 0 0.0024 11 0 0 0 7.90E+06 2.84E+06 - - - 0.5092 0.9998 221125_WJC_METTL3_EV_vs_WT_F10.05859.05859.3 6.29E-06 14/40 K.KNHEEEMNALR.G "sp|Q04695|K1C17_HUMAN,sp|P02533|K1C14_HUMAN,tr|K7EPJ9|K7EPJ9_HUMAN,tr|K7ESE1|K7ESE1_HUMAN,tr|F5GWP8|F5GWP8_HUMAN" 5 1369.6408 0.5 139312 5859 3 1369.643534 457.5542 "Keratin, type I cytoskeletal 17 OS=Homo sapiens OX=9606 GN=KRT17 PE=1 SV=2" 5.5 1571.7 - 497552 - - - 1.9618 - 2.649 0.368 - 375 1 2 0 0.0027 11 0 0 0 2.76E+07 5.50E+07 - - - 5.4096 0.9479 221125_WJC_METTL3_EV_vs_WT_F10.05863.05863.2 0.059 24-Jun R.KGTDDSMTLQSQK.F "sp|O00422|SAP18_HUMAN,tr|H7BZW6|H7BZW6_HUMAN" 2 1437.677 1.35 139316 5863 2 1437.682688 719.8458 Histone deacetylase complex subunit SAP18 OS=Homo sapiens OX=9606 GN=SAP18 PE=1 SV=1 5.96 1572.3 - 62462.3 - - - 3.9856 - 1.117 0.227 - 97.9 1 2 0 0.0057 13 0 0 0 1.97E+07 1.46E+07 - - - 0.9998 0.8922 221125_WJC_METTL3_EV_vs_WT_F10.05864.05864.2 0.000446 Apr-32 N.QGGYGGSSSSSSYGSGR.R "sp|P09651|ROA1_HUMAN,tr|A0A7I2YQX9|A0A7I2YQX9_HUMAN,tr|A0A7I2V3R8|A0A7I2V3R8_HUMAN,tr|F8W6I7|F8W6I7_HUMAN,tr|A0A7I2YQY2|A0A7I2YQY2_HUMAN,tr|H0YH80|H0YH80_HUMAN,tr|A0A2R8Y4L2|A0A2R8Y4L2_HUMAN" 7 1579.6499 1.25 139317 5864 2 1579.653595 790.8322 Heterogeneous nuclear ribonucleoprotein A1 OS=Homo sapiens OX=9606 GN=HNRNPA1 PE=1 SV=5 8.59 1572.4 - 44485.7 - - - 2.3442 - 1.02 0.49 - 46 1 1 0 0.0037 17 0 0 0 1.78E+06 1.42E+06 - - - 2.7077 0.9996 221125_WJC_METTL3_EV_vs_WT_F10.05865.05865.2 0.000126 24-May R.K[136.11]GTDDSMTLQSQK[136.11].F "sp|O00422|SAP18_HUMAN,tr|H7BZW6|H7BZW6_HUMAN" 2 1453.7054 1.35 139318 5865 2 1453.707019 727.86 Histone deacetylase complex subunit SAP18 OS=Homo sapiens OX=9606 GN=SAP18 PE=1 SV=1 5.96 1572.5 - 41813.1 - - - 1.1426 - 1.478 0.489 - 65.1 1 2 0 0.0017 13 0 0 0 1.97E+07 1.46E+07 - - - 3.6549 0.9573 221125_WJC_METTL3_EV_vs_WT_F10.05878.05878.2 0.00274 24-May T.NTGPNNSNTTFQK.R "sp|Q9NYF8|BCLF1_HUMAN,tr|H0YF14|H0YF14_HUMAN" 2 1421.6535 2.82 139327 5878 2 1421.654803 711.834 Bcl-2-associated transcription factor 1 OS=Homo sapiens OX=9606 GN=BCLAF1 PE=1 SV=2 8.75 1574.3 - 86956.5 - - - 0.9018 - 1.17 0.463 - 59.6 1 1 0 0.0013 13 0 0 0 5.72E+06 2.03E+06 - - - 2.8633 0.9999 221125_WJC_METTL3_EV_vs_WT_F10.05887.05887.3 8.82E-05 21/44 R.SKEEAEALYHSK.Y sp|P35908|K22E_HUMAN 1 1390.6729 123.41 139333 5887 3 1390.674014 464.5649 "Keratin, type II cytoskeletal 2 epidermal OS=Homo sapiens OX=9606 GN=KRT2 PE=1 SV=2" 5.47 1575.7 - 982153 - - - 0.8305 - 3.507 0.517 - 752.8 1 2 1 0.0012 12 0 0 0 2.50E+07 2.03E+05 - - - 7.7817 1 221125_WJC_METTL3_EV_vs_WT_F10.05940.05940.3 4.84E-09 18/36 R.KPEDWDERPK.L "sp|P27824|CALX_HUMAN,tr|A0A7P0T937|A0A7P0T937_HUMAN,tr|A0A7P0T840|A0A7P0T840_HUMAN,tr|A0A7P0TB65|A0A7P0TB65_HUMAN,tr|A0A7P0TAE9|A0A7P0TAE9_HUMAN,tr|D6RGY2|D6RGY2_HUMAN,tr|A0A7P0T8G1|A0A7P0T8G1_HUMAN,tr|A0A7P0Z4D6|A0A7P0Z4D6_HUMAN,tr|A0A7P0Z484|A0A7P0Z484_HUMAN,tr|A0A7P0TAR9|A0A7P0TAR9_HUMAN,tr|A0A7P0T9L0|A0A7P0T9L0_HUMAN" 11 1298.6255 1.53 139359 5940 3 1298.628634 433.8824 Calnexin OS=Homo sapiens OX=9606 GN=CANX PE=1 SV=2 4.78 1583.4 - 944656 - - - 2.4018 - 3.319 0.466 - 771.1 1 2 0 0.0031 10 0 0 0 5.36E+07 3.51E+07 - - - 7.2381 0.9934 221125_WJC_METTL3_EV_vs_WT_F10.05944.05944.3 0.0274 May-40 K.HQGSVLHPDYK.T "sp|Q9NZM4|BICRA_HUMAN,tr|A0A087WWH3|A0A087WWH3_HUMAN" 2 1279.6309 2.46 139361 5944 3 1279.632528 427.5509 BRD4-interacting chromatin-remodeling complex-associated protein OS=Homo sapiens OX=9606 GN=BICRA PE=1 SV=2 6.92 1584 - 73088.4 - - - 1.2449 - 1.255 0.29 - 21.1 3 2 0 0.0016 11 0 0 0 1.06E+07 4.31E+06 - - - 2.1972 1 221125_WJC_METTL3_EV_vs_WT_F10.05949.05949.3 2.52E-06 14/36 R.K[136.11]PEDWDER[166.11]PK[136.11].L "sp|P27824|CALX_HUMAN,tr|A0A7P0T937|A0A7P0T937_HUMAN,tr|A0A7P0T840|A0A7P0T840_HUMAN,tr|A0A7P0TB65|A0A7P0TB65_HUMAN,tr|A0A7P0TAE9|A0A7P0TAE9_HUMAN,tr|D6RGY2|D6RGY2_HUMAN,tr|A0A7P0T8G1|A0A7P0T8G1_HUMAN,tr|A0A7P0Z4D6|A0A7P0Z4D6_HUMAN,tr|A0A7P0Z484|A0A7P0Z484_HUMAN,tr|A0A7P0TAR9|A0A7P0TAR9_HUMAN,tr|A0A7P0T9L0|A0A7P0T9L0_HUMAN" 11 1324.6622 2.44 139364 5949 3 1324.664444 442.5613 Calnexin OS=Homo sapiens OX=9606 GN=CANX PE=1 SV=2 4.78 1584.7 - 578896 - - - 1.7053 - 2.646 0.462 - 413.5 1 2 0 0.0023 10 0 0 0 1.19E+08 4.86E+07 - - - 6.5319 0.9868 221125_WJC_METTL3_EV_vs_WT_F10.05950.05950.3 0.00628 Dec-36 R.R[166.11]K[136.11]EVTDEIVK[136.11].E sp|P23381|SYWC_HUMAN 1 1241.719 0.94 139365 5950 3 1241.721132 414.9136 "Tryptophan--tRNA ligase, cytoplasmic OS=Homo sapiens OX=9606 GN=WARS1 PE=1 SV=2" 6.18 1584.8 - 251159 - - - 1.7395 - 1.862 0.23 - 197.7 1 2 1 0.0022 10 0 0 0 1.32E+07 1.41E+07 - - - 2.9192 0.9889 221125_WJC_METTL3_EV_vs_WT_F10.05955.05955.2 5.52E-06 28-Sep A.SSDEEGSQDESLDSK.T "sp|Q9UBV2|SE1L1_HUMAN,tr|G3V3B3|G3V3B3_HUMAN" 2 1611.6384 1.66 139370 5955 2 1611.641257 806.8265 Protein sel-1 homolog 1 OS=Homo sapiens OX=9606 GN=SEL1L PE=1 SV=3 3.71 1585.4 - 42981.4 - - - 1.7827 - 1.837 0.659 - 179.2 1 1 0 0.0029 15 0 0 0 7.21E+06 4.34E+06 - - - 5.4026 0.9626 221125_WJC_METTL3_EV_vs_WT_F10.05960.05960.3 0.000716 Oct-40 L.STHTHVVDITR.T "sp|Q14203|DCTN1_HUMAN,tr|A0A804CDA6|A0A804CDA6_HUMAN,tr|E7EX90|E7EX90_HUMAN,tr|A0A7P0Z4C3|A0A7P0Z4C3_HUMAN,tr|E7EWF7|E7EWF7_HUMAN" 5 1264.6524 1.57 139373 5960 3 1264.654354 422.5581 Dynactin subunit 1 OS=Homo sapiens OX=9606 GN=DCTN1 PE=1 SV=3 6.66 1586.2 - 210677 - - - 1.5467 - 1.742 0.382 - 165.2 1 1 0 0.002 11 0 0 0 9.98E+06 6.37E+06 - - - 4.3751 1 221125_WJC_METTL3_EV_vs_WT_F10.05963.05963.3 4.81E-08 13/36 R.K[136.11]QDSGHLDLR[166.11].N "sp|Q86U44|MTA70_HUMAN,tr|B4E349|B4E349_HUMAN,tr|F5H6D8|F5H6D8_HUMAN,tr|B4DTN4|B4DTN4_HUMAN" 4 1185.6221 0.03 139375 5963 3 1185.623946 396.2146 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 6.75 1586.6 - 2.09E+06 - - - 1.5528 - 2.786 0.502 - 229.9 1 2 0 0.0018 10 0 0 0 3.57E+06 1.10E+08 - - - 7.1286 0.9635 221125_WJC_METTL3_EV_vs_WT_F10.05965.05965.3 0.138 Sep-44 K.EIISHISQHGGK.W "sp|A6NHR9|SMHD1_HUMAN,tr|J3KTL8|J3KTL8_HUMAN,tr|J3QSH1|J3QSH1_HUMAN" 3 1304.6837 1.34 139376 5965 3 1304.687451 435.9018 Structural maintenance of chromosomes flexible hinge domain-containing protein 1 OS=Homo sapiens OX=9606 GN=SMCHD1 PE=1 SV=2 7.01 1586.8 - 285957 - - - 2.8758 - 1.681 0.173 - 97.7 2 2 0 0.0038 12 0 0 0 1.94E+07 1.45E+07 - - - 1.7681 0.9941 221125_WJC_METTL3_EV_vs_WT_F10.05971.05971.3 1.08E-05 18/64 L.VSGLNSSASEPAK[136.11]EPAK[136.11].K "sp|Q86U44|MTA70_HUMAN,tr|F5H6D8|F5H6D8_HUMAN,tr|H0YFV6|H0YFV6_HUMAN,tr|B4DTN4|B4DTN4_HUMAN" 4 1686.8759 0 139380 5971 3 1686.877465 563.2993 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 6.11 1587.6 - 1.46E+06 - - - 0.9106 - 3.406 0.569 - 472.8 1 1 1 0.0015 17 0 0 0 8.81E+04 5.65E+07 - - - 7.9794 0.9861 221125_WJC_METTL3_EV_vs_WT_F10.05972.05972.3 3.48E-05 Nov-44 Y.R[166.11]ADTQTYQPYNK[136.11].D sp|P84090|ERH_HUMAN 1 1501.728 2.46 139381 5972 3 1501.731092 501.5833 Enhancer of rudimentary homolog OS=Homo sapiens OX=9606 GN=ERH PE=1 SV=1 8.5 1587.8 - 277289 - - - 2.0416 - 2.19 0.437 - 150.7 1 1 0 0.0031 12 0 0 0 7.66E+07 3.11E+07 - - - 5.5841 0.9879 221125_WJC_METTL3_EV_vs_WT_F10.05977.05977.3 0.00278 Jul-56 R.ALERDPTEDDVESKK.L "sp|Q86YP4|P66A_HUMAN,tr|V9GY85|V9GY85_HUMAN,tr|V9GYX5|V9GYX5_HUMAN,tr|C9JJK9|C9JJK9_HUMAN,tr|H7C3H1|H7C3H1_HUMAN,tr|C9JVY3|C9JVY3_HUMAN,tr|C9JMI3|C9JMI3_HUMAN,tr|C9JGN4|C9JGN4_HUMAN" 8 1730.8323 1.86 139384 5977 3 1730.836648 577.9514 Transcriptional repressor p66-alpha OS=Homo sapiens OX=9606 GN=GATAD2A PE=1 SV=1 4.3 1588.4 - 121284 - - - 2.5277 - 1.421 0.348 - 54.6 1 2 1 0.0044 15 0 0 0 1.33E+07 7.14E+06 - - - 3.3355 1 221125_WJC_METTL3_EV_vs_WT_F10.05978.05978.2 8.87E-08 Sep-34 R.NQGGYGGSSSSSSYGSGR.R "sp|P09651|ROA1_HUMAN,tr|A0A7I2YQX9|A0A7I2YQX9_HUMAN,tr|A0A7I2V3R8|A0A7I2V3R8_HUMAN,tr|F8W6I7|F8W6I7_HUMAN,tr|A0A7I2YQY2|A0A7I2YQY2_HUMAN,tr|H0YH80|H0YH80_HUMAN,tr|A0A2R8Y4L2|A0A2R8Y4L2_HUMAN" 7 1693.6928 1.25 139385 5978 2 1693.694826 847.8537 Heterogeneous nuclear ribonucleoprotein A1 OS=Homo sapiens OX=9606 GN=HNRNPA1 PE=1 SV=5 8.59 1588.5 - 76816 - - - 1.185 - 1.878 0.712 - 214.7 1 2 0 0.002 18 0 0 0 5.56E+06 4.44E+06 - - - 5.8486 0.9997 221125_WJC_METTL3_EV_vs_WT_F10.05979.05979.2 0.000171 Jun-34 R.NQGGYGGSSSSSSYGSGR[166.11].R "sp|P09651|ROA1_HUMAN,tr|A0A7I2YQX9|A0A7I2YQX9_HUMAN,tr|A0A7I2V3R8|A0A7I2V3R8_HUMAN,tr|F8W6I7|F8W6I7_HUMAN,tr|A0A7I2YQY2|A0A7I2YQY2_HUMAN,tr|H0YH80|H0YH80_HUMAN,tr|A0A2R8Y4L2|A0A2R8Y4L2_HUMAN" 7 1703.7011 1.25 139386 5979 2 1703.703996 852.8578 Heterogeneous nuclear ribonucleoprotein A1 OS=Homo sapiens OX=9606 GN=HNRNPA1 PE=1 SV=5 8.59 1588.7 - 70692.2 - - - 1.7063 - 1.565 0.607 - 80.1 1 2 0 0.0029 18 0 0 0 5.56E+06 4.44E+06 - - - 4.6245 0.996 221125_WJC_METTL3_EV_vs_WT_F10.05991.05991.3 0.112 May-60 R.VQVVDEEGDQQHQEGK[136.11].R "sp|Q02447|SP3_HUMAN,tr|A0A494C0Z6|A0A494C0Z6_HUMAN,tr|A0A494C1G8|A0A494C1G8_HUMAN,tr|H0Y6K5|H0Y6K5_HUMAN,tr|H0Y7L6|H0Y7L6_HUMAN,tr|A0A494C070|A0A494C070_HUMAN" 6 1831.8428 1.09 139391 5991 3 1831.844357 611.6215 Transcription factor Sp3 OS=Homo sapiens OX=9606 GN=SP3 PE=1 SV=3 4.17 1590.6 - 76617.6 - - - 0.8582 - 0.94 0.361 - 24.8 1 2 0 0.0016 16 0 0 0 1.29E+07 1.18E+07 - - - 2.4056 0.8419 221125_WJC_METTL3_EV_vs_WT_F10.06000.06000.3 2.2 Sep-36 K.NLDISR[166.11]PDK[136.11]K[136.11].S "sp|P46977|STT3A_HUMAN,tr|H0YET6|H0YET6_HUMAN" 2 1210.688 0.99 139397 6000 3 1210.689848 404.5699 Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit STT3A OS=Homo sapiens OX=9606 GN=STT3A PE=1 SV=2 8.59 1591.7 - 475170 - - - 1.5214 - 1.343 0.099 - 84 2 2 0 0.0018 10 0 0 0 3.50E+07 3.52E+07 - - - 0.3652 0.9994 221125_WJC_METTL3_EV_vs_WT_F10.06002.06002.3 0.00693 Dec-32 K.TKFPYTNHR.T "sp|O00443|P3C2A_HUMAN,tr|A0A0C4DGF9|A0A0C4DGF9_HUMAN" 2 1162.5883 0.67 139398 6002 3 1162.589787 388.5367 Phosphatidylinositol 4-phosphate 3-kinase C2 domain-containing subunit alpha OS=Homo sapiens OX=9606 GN=PIK3C2A PE=1 SV=2 9.99 1591.9 - 285624 - - - 1.2429 - 2.035 0.407 - 249.4 1 2 1 0.0014 9 0 0 0 3.66E+07 5.49E+07 - - - 5.2185 0.9998 221125_WJC_METTL3_EV_vs_WT_F10.06011.06011.3 0.000126 Aug-60 R.VQVVDEEGDQQHQEGK.R "sp|Q02447|SP3_HUMAN,tr|A0A494C0Z6|A0A494C0Z6_HUMAN,tr|A0A494C1G8|A0A494C1G8_HUMAN,tr|H0Y6K5|H0Y6K5_HUMAN,tr|H0Y7L6|H0Y7L6_HUMAN,tr|A0A494C070|A0A494C070_HUMAN" 6 1823.8286 1.09 139404 6011 3 1823.830592 608.9501 Transcription factor Sp3 OS=Homo sapiens OX=9606 GN=SP3 PE=1 SV=3 4.17 1593.1 - 130056 - - - 1.1004 - 1.58 0.467 - 68.9 1 2 0 0.002 16 0 0 0 1.28E+07 1.18E+07 - - - 4.9197 0.9999 221125_WJC_METTL3_EV_vs_WT_F10.06013.06013.3 7.77E-05 Sep-48 R.QNYHQDSEAAINR.Q "sp|P02794|FRIH_HUMAN,tr|E9PRK8|E9PRK8_HUMAN,tr|E9PKY7|E9PKY7_HUMAN,tr|E9PQR3|E9PQR3_HUMAN,tr|E9PKM5|E9PKM5_HUMAN,tr|E9PK45|E9PK45_HUMAN" 6 1544.6968 1.81 139405 6013 3 1544.701776 515.9062 Ferritin heavy chain OS=Homo sapiens OX=9606 GN=FTH1 PE=1 SV=2 5.32 1593.3 - 342483 - - - 3.233 - 2.14 0.532 - 158.5 1 2 0 0.005 13 0 0 0 2.36E+07 1.30E+07 - - - 6.5327 0.9998 221125_WJC_METTL3_EV_vs_WT_F10.06017.06017.3 0.000182 Nov-40 R.K[136.11]AHLTNQYMQR[166.11].V "sp|Q13310|PABP4_HUMAN,tr|A0A7I2V5W9|A0A7I2V5W9_HUMAN,tr|H0YEU6|H0YEU6_HUMAN,tr|B1ANR0|B1ANR0_HUMAN,tr|A0A7I2V4L7|A0A7I2V4L7_HUMAN,tr|A0A7I2V598|A0A7I2V598_HUMAN,tr|A0A7I2V4V6|A0A7I2V4V6_HUMAN,tr|H0Y5F5|H0Y5F5_HUMAN" 8 1406.7208 1.07 139407 6017 3 1406.722777 469.9142 Polyadenylate-binding protein 4 OS=Homo sapiens OX=9606 GN=PABPC4 PE=1 SV=1 9.99 1593.8 - 290662 - - - 1.4246 - 1.942 0.387 - 223.2 1 2 0 0.002 11 0 0 0 6.01E+07 5.59E+07 - - - 4.7396 0.9999 221125_WJC_METTL3_EV_vs_WT_F10.06019.06019.3 1.71E-05 Sep-48 R.QNYHQDSEAAINR[166.11].Q "sp|P02794|FRIH_HUMAN,tr|E9PRK8|E9PRK8_HUMAN,tr|E9PKY7|E9PKY7_HUMAN,tr|E9PQR3|E9PQR3_HUMAN,tr|E9PKM5|E9PKM5_HUMAN,tr|E9PK45|E9PK45_HUMAN" 6 1554.7051 1.81 139409 6019 3 1554.707775 519.2423 Ferritin heavy chain OS=Homo sapiens OX=9606 GN=FTH1 PE=1 SV=2 5.32 1594.1 - 232509 - - - 1.7515 - 1.856 0.542 - 77 1 2 0 0.0027 13 0 0 0 2.36E+07 1.30E+07 - - - 6.2587 1 221125_WJC_METTL3_EV_vs_WT_F10.06024.06024.3 2.17E-06 14/40 R.R[166.11]LPDAHSDYAR[166.11].Y sp|Q96PK6|RBM14_HUMAN 1 1319.6485 2.27 139411 6024 3 1319.65066 440.8901 RNA-binding protein 14 OS=Homo sapiens OX=9606 GN=RBM14 PE=1 SV=2 6.75 1594.7 - 484294 - - - 1.6088 - 2.614 0.516 - 271.8 1 2 0 0.0021 11 0 0 0 2.46E+08 1.08E+08 - - - 7.022 0.9257 221125_WJC_METTL3_EV_vs_WT_F10.06039.06039.2 0.829 20-Apr R.RLPDAHSDYAR.Y sp|Q96PK6|RBM14_HUMAN 1 1299.632 2.1 139420 6039 2 1299.636299 650.8233 RNA-binding protein 14 OS=Homo sapiens OX=9606 GN=RBM14 PE=1 SV=2 6.75 1597 - 49444.3 - - - 3.3102 - 0.819 0.258 - 25.9 1 2 0 0.0043 11 0 0 0 4.84E+06 2.31E+06 - - - 0.4051 0.9954 221125_WJC_METTL3_EV_vs_WT_F10.06044.06044.2 0.192 20-May R.R[166.11]LPDAHSDYAR[166.11].Y sp|Q96PK6|RBM14_HUMAN 1 1319.6485 2.1 139423 6044 2 1319.65196 660.8315 RNA-binding protein 14 OS=Homo sapiens OX=9606 GN=RBM14 PE=1 SV=2 6.75 1597.7 - 39125.7 - - - 2.5939 - 1.144 0.368 - 45.6 1 2 0 0.0034 11 0 0 0 4.84E+06 2.31E+06 - - - 2.1219 0.9966 221125_WJC_METTL3_EV_vs_WT_F10.06049.06049.3 0.00601 Jul-48 R.KGTDDSMTLQSQK.F "sp|O00422|SAP18_HUMAN,tr|H7BZW6|H7BZW6_HUMAN" 2 1437.677 1.33 139426 6049 3 1437.679085 480.2329 Histone deacetylase complex subunit SAP18 OS=Homo sapiens OX=9606 GN=SAP18 PE=1 SV=1 5.96 1598.3 - 124594 - - - 1.4795 - 1.463 0.282 - 61.9 1 2 0 0.0021 13 0 0 0 2.56E+08 1.92E+08 - - - 2.715 0.9988 221125_WJC_METTL3_EV_vs_WT_F10.06050.06050.3 0.0504 Sep-40 K.R[166.11]EEHLSEEAIK[136.11].V "sp|Q6ULP2|AFTIN_HUMAN,tr|A0A0A0MSN6|A0A0A0MSN6_HUMAN,tr|B8ZZI9|B8ZZI9_HUMAN" 3 1357.6957 1.94 139427 6050 3 1357.696921 453.5725 Aftiphilin OS=Homo sapiens OX=9606 GN=AFTPH PE=1 SV=3 4.91 1598.4 - 145821 - - - 0.9266 - 1.656 0.291 - 112 1 2 0 0.0013 11 0 0 0 6.81E+07 3.52E+07 - - - 3.2169 0.9999 221125_WJC_METTL3_EV_vs_WT_F10.06051.06051.3 8.15E-06 15/40 K.REEHLSEEAIK.V "sp|Q6ULP2|AFTIN_HUMAN,tr|A0A0A0MSN6|A0A0A0MSN6_HUMAN,tr|B8ZZI9|B8ZZI9_HUMAN" 3 1339.6732 1.94 139428 6051 3 1339.677288 447.565 Aftiphilin OS=Homo sapiens OX=9606 GN=AFTPH PE=1 SV=3 4.91 1598.6 - 257285 - - - 3.0567 - 2.559 0.501 - 317.2 1 2 0 0.0041 11 0 0 0 6.82E+07 3.52E+07 - - - 6.7938 0.9968 221125_WJC_METTL3_EV_vs_WT_F10.06053.06053.3 0.0106 13/44 K.RSFSSQRPVVDR.Q "sp|Q5JSZ5|PRC2B_HUMAN,tr|A0A804HKC3|A0A804HKC3_HUMAN,tr|A0A804HJR4|A0A804HJR4_HUMAN" 3 1432.7535 1.3 139430 6053 3 1432.759196 478.5918 Protein PRRC2B OS=Homo sapiens OX=9606 GN=PRRC2B PE=1 SV=2 11.7 1598.8 - 144432 - - - 3.9693 - 1.804 0.342 - 159.5 1 2 0 0.0057 12 0 0 0 6.31E+06 4.87E+06 - - - 3.9868 0.9958 221125_WJC_METTL3_EV_vs_WT_F10.06057.06057.3 0.0128 Aug-44 K.R[166.11]SFSSQR[166.11]PVVDR[166.11].Q "sp|Q5JSZ5|PRC2B_HUMAN,tr|A0A804HKC3|A0A804HKC3_HUMAN,tr|A0A804HJR4|A0A804HJR4_HUMAN" 3 1462.7783 1.3 139432 6057 3 1462.780375 488.6 Protein PRRC2B OS=Homo sapiens OX=9606 GN=PRRC2B PE=1 SV=2 11.7 1599.4 - 150802 - - - 1.4055 - 1.605 0.241 - 50 1 2 0 0.0021 12 0 0 0 6.31E+06 4.87E+06 - - - 2.5378 0.9991 221125_WJC_METTL3_EV_vs_WT_F10.06059.06059.2 0.00968 26-Jun K.QGQSNSGVVQVQQK[136.11].V "sp|Q12830|BPTF_HUMAN,tr|F5GXF5|F5GXF5_HUMAN,tr|E9PE19|E9PE19_HUMAN,tr|E7ETD6|E7ETD6_HUMAN,tr|A0A2R8Y7Q1|A0A2R8Y7Q1_HUMAN" 5 1493.7678 0.59 139434 6059 2 1493.770246 747.8912 Nucleosome-remodeling factor subunit BPTF OS=Homo sapiens OX=9606 GN=BPTF PE=1 SV=3 8.75 1599.7 - 76886.3 - - - 1.6582 - 1.408 0.431 - 67.8 1 2 0 0.0025 14 0 0 0 2.17E+06 3.68E+06 - - - 3.0822 0.9929 221125_WJC_METTL3_EV_vs_WT_F10.06066.06066.3 0.135 Jun-60 R.GSPDGSLQTGKPSAPK.K "sp|Q8IZL8|PELP1_HUMAN,tr|E7EV54|E7EV54_HUMAN,tr|C9JFV4|C9JFV4_HUMAN" 3 1525.7736 0.61 139438 6066 3 1525.769629 509.5985 "Proline-, glutamic acid- and leucine-rich protein 1 OS=Homo sapiens OX=9606 GN=PELP1 PE=1 SV=2" 8.59 1600.7 - 114690 - - - -2.6262 - 1.463 0.296 - 37.9 2 2 0 -0.004 16 0 0 0 1.21E+07 1.98E+07 - - - 2.676 0.9998 221125_WJC_METTL3_EV_vs_WT_F10.06070.06070.3 5.14E-07 13/40 R.R[166.11]NEQLTLHDER[166.11].F "sp|Q96GA3|LTV1_HUMAN,tr|A0A075B6Q4|A0A075B6Q4_HUMAN" 2 1429.7177 0.94 139440 6070 3 1429.720809 477.5798 Protein LTV1 homolog OS=Homo sapiens OX=9606 GN=LTV1 PE=1 SV=1 5.45 1601.3 - 232970 - - - 2.1885 - 2.433 0.362 - 261.9 1 2 0 0.0031 11 0 0 0 8.43E+06 8.93E+06 - - - 5.1009 0.9975 221125_WJC_METTL3_EV_vs_WT_F10.06078.06078.3 0.154 Oct-36 K.VSELK[136.11]EELK[136.11]K[136.11].R "sp|Q00839|HNRPU_HUMAN,tr|A0A1W2PPS1|A0A1W2PPS1_HUMAN,tr|A0A1X7SBS1|A0A1X7SBS1_HUMAN" 3 1225.7344 0.94 139444 6078 3 1225.734536 409.5854 Heterogeneous nuclear ribonucleoprotein U OS=Homo sapiens OX=9606 GN=HNRNPU PE=1 SV=6 6.2 1602.4 - 722125 - - - 0.1077 - 1.69 0.33 - 122.4 1 2 1 0.0001 10 0 0 0 8.65E+07 9.22E+07 - - - 3.7516 0.9996 221125_WJC_METTL3_EV_vs_WT_F10.06085.06085.2 2.00E-05 26-Sep K.QGQSNSGVVQVQQK.V "sp|Q12830|BPTF_HUMAN,tr|F5GXF5|F5GXF5_HUMAN,tr|E9PE19|E9PE19_HUMAN,tr|E7ETD6|E7ETD6_HUMAN,tr|A0A2R8Y7Q1|A0A2R8Y7Q1_HUMAN" 5 1485.7536 0.59 139449 6085 2 1485.756989 743.8841 Nucleosome-remodeling factor subunit BPTF OS=Homo sapiens OX=9606 GN=BPTF PE=1 SV=3 8.75 1603.3 - 94705.9 - - - 2.3019 - 2.021 0.511 - 296.4 1 2 0 0.0034 14 0 0 0 2.17E+06 3.68E+06 - - - 4.5798 0.9978 221125_WJC_METTL3_EV_vs_WT_F10.06088.06088.3 0.000342 15/44 Y.RADTQTYQPYNK.D sp|P84090|ERH_HUMAN 1 1483.7056 2.42 139450 6088 3 1483.705352 495.5758 Enhancer of rudimentary homolog OS=Homo sapiens OX=9606 GN=ERH PE=1 SV=1 8.5 1603.7 - 845063 - - - -0.1375 - 2.855 0.496 - 286.6 1 1 0 -0.0002 12 0 0 0 7.71E+07 3.18E+07 - - - 6.9777 0.9821 221125_WJC_METTL3_EV_vs_WT_F10.06096.06096.2 4.66 20-Jun K.REEHLSEEAIK.V "sp|Q6ULP2|AFTIN_HUMAN,tr|A0A0A0MSN6|A0A0A0MSN6_HUMAN,tr|B8ZZI9|B8ZZI9_HUMAN" 3 1339.6732 2.75 139456 6096 2 1339.673108 670.8439 Aftiphilin OS=Homo sapiens OX=9606 GN=AFTPH PE=1 SV=3 4.91 1604.8 - 120871 - - - -0.0634 - 1.209 0.091 - 94.8 1 2 0 -0.0001 11 0 0 0 1.31E+06 4.77E+05 - - - 0.2265 0.9997 221125_WJC_METTL3_EV_vs_WT_F10.06100.06100.3 0.000422 Sep-52 K.FKEQEQDDSTVAC[160.03]R.F sp|Q7LBC6|KDM3B_HUMAN 1 1711.7472 1.17 139460 6100 3 1711.747049 571.5897 Lysine-specific demethylase 3B OS=Homo sapiens OX=9606 GN=KDM3B PE=1 SV=2 4.32 1605.3 - 130510 - - - -0.0666 - 1.964 0.473 - 129.5 1 2 1 -0.0001 14 0 0 0 9.92E+06 8.51E+06 - - - 5.6072 0.9998 221125_WJC_METTL3_EV_vs_WT_F10.06105.06105.3 5.38E-05 Nov-60 R.GSPDGSLQTGK[136.11]PSAPK[136.11].K "sp|Q8IZL8|PELP1_HUMAN,tr|E7EV54|E7EV54_HUMAN,tr|C9JFV4|C9JFV4_HUMAN" 3 1541.802 0.58 139464 6105 3 1541.801629 514.9413 "Proline-, glutamic acid- and leucine-rich protein 1 OS=Homo sapiens OX=9606 GN=PELP1 PE=1 SV=2" 8.59 1606 - 424882 - - - -0.264 - 2.03 0.378 - 122.7 1 2 0 -0.0004 16 0 0 0 1.21E+07 2.10E+07 - - - 4.5709 0.999 221125_WJC_METTL3_EV_vs_WT_F10.06113.06113.2 4.03E-06 18-Nov K.VSELK[136.11]EELK[136.11]K[136.11].R "sp|Q00839|HNRPU_HUMAN,tr|A0A1W2PPS1|A0A1W2PPS1_HUMAN,tr|A0A1X7SBS1|A0A1X7SBS1_HUMAN" 3 1225.7344 1 139470 6113 2 1225.734178 613.8745 Heterogeneous nuclear ribonucleoprotein U OS=Homo sapiens OX=9606 GN=HNRNPU PE=1 SV=6 6.2 1606.9 - 379707 - - - -0.1844 - 2.334 0.563 - 336.3 1 2 1 -0.0002 10 0 0 0 5.16E+06 5.15E+06 - - - 5.5651 0.9989 221125_WJC_METTL3_EV_vs_WT_F10.06114.06114.3 0.00493 14/36 K.VSELKEELKK.R "sp|Q00839|HNRPU_HUMAN,tr|A0A1W2PPS1|A0A1W2PPS1_HUMAN,tr|A0A1X7SBS1|A0A1X7SBS1_HUMAN" 3 1201.6918 0.93 139471 6114 3 1201.691767 401.5712 Heterogeneous nuclear ribonucleoprotein U OS=Homo sapiens OX=9606 GN=HNRNPU PE=1 SV=6 6.2 1607 - 5.37E+06 - - - -0.0308 - 2.238 0.314 - 282 1 2 1 0 10 0 0 0 8.57E+07 9.22E+07 - - - 4.3934 0.9988 221125_WJC_METTL3_EV_vs_WT_F10.06116.06116.2 0.00144 14/18 K.VSELKEELKK.R "sp|Q00839|HNRPU_HUMAN,tr|A0A1W2PPS1|A0A1W2PPS1_HUMAN,tr|A0A1X7SBS1|A0A1X7SBS1_HUMAN" 3 1201.6918 1 139473 6116 2 1201.691381 601.8532 Heterogeneous nuclear ribonucleoprotein U OS=Homo sapiens OX=9606 GN=HNRNPU PE=1 SV=6 6.2 1607.3 - 302038 - - - -0.352 - 2.705 0.45 - 698.3 1 2 1 -0.0004 10 0 0 0 5.12E+06 5.15E+06 - - - 5.1422 0.8982 221125_WJC_METTL3_EV_vs_WT_F10.06124.06124.2 0.00311 16-Dec V.SELKEELKK.R "sp|Q00839|HNRPU_HUMAN,tr|A0A1W2PPS1|A0A1W2PPS1_HUMAN,tr|A0A1X7SBS1|A0A1X7SBS1_HUMAN" 3 1102.6234 1 139479 6124 2 1102.622892 552.319 Heterogeneous nuclear ribonucleoprotein U OS=Homo sapiens OX=9606 GN=HNRNPU PE=1 SV=6 5.95 1608.3 - 467055 - - - -0.4517 - 2.395 0.377 - 484.2 1 1 1 -0.0005 9 0 0 0 5.55E+06 5.53E+06 - - - 4.3521 1 221125_WJC_METTL3_EV_vs_WT_F10.06127.06127.3 5.92E-06 Dec-44 K.TFSQSSHLVQHR[166.11].R sp|Q6DD87|ZN787_HUMAN 1 1435.7196 0.7 139482 6127 3 1435.719769 479.5805 Zinc finger protein 787 OS=Homo sapiens OX=9606 GN=ZNF787 PE=1 SV=4 9.47 1608.7 - 217290 - - - 0.1316 - 2.385 0.538 - 181.3 1 2 0 0.0002 12 0 0 0 1.36E+07 1.93E+07 - - - 6.9474 0.9999 221125_WJC_METTL3_EV_vs_WT_F10.06135.06135.3 7.35E-05 Nov-52 K.FK[136.11]EQEQDDSTVAC[160.03]R[166.11].F sp|Q7LBC6|KDM3B_HUMAN 1 1729.7696 1.14 139488 6135 3 1729.769297 577.5972 Lysine-specific demethylase 3B OS=Homo sapiens OX=9606 GN=KDM3B PE=1 SV=2 4.32 1609.7 - 388941 - - - -0.1942 - 2.316 0.527 - 199.5 1 2 1 -0.0003 14 0 0 0 9.70E+06 8.49E+06 - - - 6.6473 0.9992 221125_WJC_METTL3_EV_vs_WT_F10.06138.06138.3 0.0353 Nov-40 K.SESPK[136.11]EPEQLR[166.11].K "sp|P09651|ROA1_HUMAN,tr|F8W646|F8W646_HUMAN,tr|A0A7I2V3R8|A0A7I2V3R8_HUMAN,tr|F8VTQ5|F8VTQ5_HUMAN,tr|A0A7I2YQ85|A0A7I2YQ85_HUMAN,tr|F8W6I7|F8W6I7_HUMAN,tr|A0A7I2V2L6|A0A7I2V2L6_HUMAN,tr|A0A7I2V3W0|A0A7I2V3W0_HUMAN" 8 1316.6691 1.1 139491 6138 3 1316.670743 439.897 Heterogeneous nuclear ribonucleoprotein A1 OS=Homo sapiens OX=9606 GN=HNRNPA1 PE=1 SV=5 4.78 1610.1 - 220777 - - - 1.2372 - 2.087 0.385 - 240 1 2 1 0.0016 11 0 0 0 1.00E+07 9.15E+06 - - - 4.922 0.901 221125_WJC_METTL3_EV_vs_WT_F10.06147.06147.3 5.56E-05 15/60 R.PSADLTNSSAPSPSHK.V "sp|Q7KZI7|MARK2_HUMAN,tr|A0A0A0MRU9|A0A0A0MRU9_HUMAN,tr|E7ETY4|E7ETY4_HUMAN,tr|A0A7I2YQR3|A0A7I2YQR3_HUMAN,tr|E9PC69|E9PC69_HUMAN,tr|A0A7I2V3R3|A0A7I2V3R3_HUMAN" 6 1594.7587 0.82 139498 6147 3 1594.765502 532.5935 Serine\threonine-protein kinase MARK2 OS=Homo sapiens OX=9606 GN=MARK2 PE=1 SV=2 7.17 1611.3 - 345064 - - - 4.2564 - 2.649 0.366 - 315.1 1 1 0 0.0068 16 0 0 0 1.45E+07 1.77E+07 - - - 5.1183 0.9998 221125_WJC_METTL3_EV_vs_WT_F10.06151.06151.3 7.09E-08 13/40 K.QEFEKQDELKR.S "sp|O75155|CAND2_HUMAN,sp|Q86VP6|CAND1_HUMAN,tr|A0A0C4DGH5|A0A0C4DGH5_HUMAN" 3 1448.726 0.87 139500 6151 3 1448.72872 483.9159 Cullin-associated NEDD8-dissociated protein 2 OS=Homo sapiens OX=9606 GN=CAND2 PE=1 SV=3 4.87 1611.9 - 779486 - - - 1.9072 - 2.496 0.523 - 261.5 1 2 1 0.0028 11 0 0 0 7.66E+06 8.75E+06 - - - 6.9686 0.8609 221125_WJC_METTL3_EV_vs_WT_F10.06153.06153.3 0.000375 Dec-48 K.DKNQDLC[160.03]QQEAVK.G "sp|Q14554|PDIA5_HUMAN,tr|H7C4F9|H7C4F9_HUMAN" 2 1574.7359 0.58 139502 6153 3 1574.74426 525.9192 Protein disulfide-isomerase A5 OS=Homo sapiens OX=9606 GN=PDIA5 PE=1 SV=1 4.56 1612.1 - 353177 - - - 5.3279 - 1.805 0.252 - 128.2 1 2 1 0.0084 13 0 0 0 5.96E+06 1.03E+07 - - - 2.9484 0.9999 221125_WJC_METTL3_EV_vs_WT_F10.06156.06156.2 1.99E-07 26-Oct R.NYQQNYQNSESGEK.N "sp|P67809|YBOX1_HUMAN,tr|H0Y449|H0Y449_HUMAN,tr|C9J5V9|C9J5V9_HUMAN" 3 1687.7074 1.1 139505 6156 2 1687.706253 844.861 Y-box-binding protein 1 OS=Homo sapiens OX=9606 GN=YBX1 PE=1 SV=3 4.53 1612.5 - 108621 - - - -0.6838 - 2.248 0.629 - 279.8 1 2 0 -0.0012 14 0 0 0 9.65E+06 8.80E+06 - - - 5.7192 0.9999 221125_WJC_METTL3_EV_vs_WT_F10.06161.06161.3 8.66E-05 Dec-52 K.ANGTTVHVGIHPSK.V "sp|Q9UNX3|RL26L_HUMAN,sp|P61254|RL26_HUMAN,tr|J3QQQ9|J3QQQ9_HUMAN,tr|E5RIT6|E5RIT6_HUMAN,tr|J3QQV1|J3QQV1_HUMAN,tr|J3QRC4|J3QRC4_HUMAN,tr|J3KS10|J3KS10_HUMAN,tr|J3QRI7|J3QRI7_HUMAN" 8 1416.7474 0.88 139508 6161 3 1416.751553 473.2564 60S ribosomal protein L26-like 1 OS=Homo sapiens OX=9606 GN=RPL26L1 PE=1 SV=1 8.81 1613.2 - 1.49E+06 - - - 2.9589 - 2.622 0.457 - 221.6 1 2 0 0.0042 14 0 0 0 3.30E+07 3.74E+07 - - - 6.1956 0.9974 221125_WJC_METTL3_EV_vs_WT_F10.06170.06170.3 0.000779 Nov-40 K.SESPKEPEQLR.K "sp|P09651|ROA1_HUMAN,tr|F8W646|F8W646_HUMAN,tr|A0A7I2V3R8|A0A7I2V3R8_HUMAN,tr|F8VTQ5|F8VTQ5_HUMAN,tr|A0A7I2YQ85|A0A7I2YQ85_HUMAN,tr|F8W6I7|F8W6I7_HUMAN,tr|A0A7I2V2L6|A0A7I2V2L6_HUMAN,tr|A0A7I2V3W0|A0A7I2V3W0_HUMAN" 8 1298.6466 0.92 139516 6170 3 1298.650288 433.8895 Heterogeneous nuclear ribonucleoprotein A1 OS=Homo sapiens OX=9606 GN=HNRNPA1 PE=1 SV=5 4.78 1614.3 - 552495 - - - 2.806 - 2.412 0.328 - 216.4 1 2 1 0.0036 11 0 0 0 1.03E+07 1.12E+07 - - - 4.6971 0.9999 221125_WJC_METTL3_EV_vs_WT_F10.06172.06172.3 0.00197 13/44 R.REEESLAVPAKR.R "sp|Q8N9M1|CS047_HUMAN,tr|A0A804HLH2|A0A804HLH2_HUMAN,tr|J3QKZ5|J3QKZ5_HUMAN" 3 1383.747 0.94 139518 6172 3 1383.750968 462.2563 Uncharacterized protein C19orf47 OS=Homo sapiens OX=9606 GN=C19orf47 PE=1 SV=1 6.23 1614.5 - 611342 - - - 2.8481 - 2.536 0.451 - 302.1 1 2 0 0.0039 12 0 0 0 8.50E+06 9.01E+06 - - - 6.1466 0.9999 221125_WJC_METTL3_EV_vs_WT_F10.06175.06175.3 5.63E-05 14/60 K.QVQPQVQPQAHSQPPR.Q "sp|Q9ULV3|CIZ1_HUMAN,tr|F5H2X7|F5H2X7_HUMAN,tr|H0Y5D5|H0Y5D5_HUMAN" 3 1823.9391 3.21 139521 6175 3 1823.943482 608.987 Cip1-interacting zinc finger protein OS=Homo sapiens OX=9606 GN=CIZ1 PE=1 SV=2 9.76 1614.9 - 180501 - - - 2.4146 - 2.66 0.448 - 248.5 1 2 0 0.0044 16 0 0 0 2.11E+08 6.57E+07 - - - 6.0438 1 221125_WJC_METTL3_EV_vs_WT_F10.06176.06176.3 2.31E-07 Nov-60 K.ASAQDAGDHVQPPEGR[166.11].D sp|Q96BK5|PINX1_HUMAN 1 1643.7527 1.46 139522 6176 3 1643.755246 548.9249 PIN2\TERF1-interacting telomerase inhibitor 1 OS=Homo sapiens OX=9606 GN=PINX1 PE=1 SV=2 4.54 1615.1 - 169187 - - - 1.53 - 2.097 0.624 - 126.5 1 2 0 0.0025 16 0 0 0 1.73E+07 1.19E+07 - - - 7.3963 0.9648 221125_WJC_METTL3_EV_vs_WT_F10.06185.06185.3 0.000173 13/44 N.GTTVHVGIHPSK[136.11].V "sp|Q9UNX3|RL26L_HUMAN,sp|P61254|RL26_HUMAN,tr|J3QQQ9|J3QQQ9_HUMAN,tr|E5RIT6|E5RIT6_HUMAN,tr|J3QQV1|J3QQV1_HUMAN,tr|J3QRC4|J3QRC4_HUMAN,tr|J3KS10|J3KS10_HUMAN,tr|J3QRI7|J3QRI7_HUMAN" 8 1239.6815 1.58 139529 6185 3 1239.684606 414.2344 60S ribosomal protein L26-like 1 OS=Homo sapiens OX=9606 GN=RPL26L1 PE=1 SV=1 8.76 1616.3 - 275090 - - - 2.4893 - 2.331 0.365 - 168.7 1 1 0 0.0031 12 0 0 0 6.99E+06 4.43E+06 - - - 4.9543 0.7745 221125_WJC_METTL3_EV_vs_WT_F10.06187.06187.3 0.000382 Oct-68 R.GGSNGGSNVGMEDGER[166.11]PR[166.11].R sp|P48634|PRC2A_HUMAN 1 1794.7818 0.61 139531 6187 3 1795.769808 599.2679 Protein PRRC2A OS=Homo sapiens OX=9606 GN=PRRC2A PE=1 SV=3 4.68 1616.6 - 217372 - - - 550.482 - 1.933 0.496 - 107.4 1 2 0 0.988 18 0 0 0 2.03E+05 3.30E+05 - - - 5.4374 1 221125_WJC_METTL3_EV_vs_WT_F10.06188.06188.3 4.07E-09 15/60 K.QVQPQVQPQAHSQPPR[166.11].Q "sp|Q9ULV3|CIZ1_HUMAN,tr|F5H2X7|F5H2X7_HUMAN,tr|H0Y5D5|H0Y5D5_HUMAN" 3 1833.9473 3.21 139532 6188 3 1833.951341 612.3231 Cip1-interacting zinc finger protein OS=Homo sapiens OX=9606 GN=CIZ1 PE=1 SV=2 9.76 1616.7 - 183418 - - - 2.1773 - 2.794 0.568 - 249.2 1 2 0 0.004 16 0 0 0 2.11E+08 6.57E+07 - - - 7.5079 0.9995 221125_WJC_METTL3_EV_vs_WT_F10.06191.06191.2 0.00426 26-Jul K.ANGTTVHVGIHPSK.V "sp|Q9UNX3|RL26L_HUMAN,sp|P61254|RL26_HUMAN,tr|J3QQQ9|J3QQQ9_HUMAN,tr|E5RIT6|E5RIT6_HUMAN,tr|J3QQV1|J3QQV1_HUMAN,tr|J3QRC4|J3QRC4_HUMAN,tr|J3KS10|J3KS10_HUMAN,tr|J3QRI7|J3QRI7_HUMAN" 8 1416.7474 0.79 139535 6191 2 1416.74908 709.381 60S ribosomal protein L26-like 1 OS=Homo sapiens OX=9606 GN=RPL26L1 PE=1 SV=1 8.81 1617.1 - 56256.7 - - - 1.2133 - 1.246 0.506 - 133.3 1 2 0 0.0017 14 0 0 0 6.41E+05 8.11E+05 - - - 3.3297 1 221125_WJC_METTL3_EV_vs_WT_F10.06193.06193.3 4.63E-07 14/36 R.K[136.11]QDSGHLDLR[166.11].N "sp|Q86U44|MTA70_HUMAN,tr|B4E349|B4E349_HUMAN,tr|F5H6D8|F5H6D8_HUMAN,tr|B4DTN4|B4DTN4_HUMAN" 4 1185.6221 0.03 139536 6193 3 1185.624191 396.2146 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 6.75 1617.3 - 1.91E+06 - - - 1.7594 - 2.567 0.553 - 236.8 1 2 0 0.0021 10 0 0 0 3.43E+06 1.01E+08 - - - 7.458 0.9999 221125_WJC_METTL3_EV_vs_WT_F10.06195.06195.3 4.38E-06 Dec-52 R.NYQQNYQNSESGEK[136.11].N "sp|P67809|YBOX1_HUMAN,tr|H0Y449|H0Y449_HUMAN,tr|C9J5V9|C9J5V9_HUMAN" 3 1695.7216 1.18 139537 6195 3 1695.725045 566.2478 Y-box-binding protein 1 OS=Homo sapiens OX=9606 GN=YBX1 PE=1 SV=3 4.53 1617.6 - 347794 - - - 2.0275 - 2.057 0.557 - 132.7 1 2 0 0.0034 14 0 0 0 3.73E+06 3.17E+06 - - - 6.6658 0.9999 221125_WJC_METTL3_EV_vs_WT_F10.06197.06197.3 0.000214 Nov-52 R.NYQQNYQNSESGEK.N "sp|P67809|YBOX1_HUMAN,tr|H0Y449|H0Y449_HUMAN,tr|C9J5V9|C9J5V9_HUMAN" 3 1687.7074 1.21 139539 6197 3 1687.712372 563.5764 Y-box-binding protein 1 OS=Homo sapiens OX=9606 GN=YBX1 PE=1 SV=3 4.53 1617.8 - 471438 - - - 2.9419 - 1.947 0.545 - 120.7 1 2 0 0.005 14 0 0 0 3.99E+06 3.29E+06 - - - 6.3855 0.9995 221125_WJC_METTL3_EV_vs_WT_F10.06198.06198.4 0.00231 Nov-78 K.FGVSSESKPEEVKK.D sp|P49790|NU153_HUMAN 1 1549.7988 1.5 139540 6198 4 1549.800551 388.457 Nuclear pore complex protein Nup153 OS=Homo sapiens OX=9606 GN=NUP153 PE=1 SV=2 6.23 1618 - 267939 - - - 1.1376 - 1.958 0.336 - 43.3 1 2 0 0.0018 14 0 0 0 1.13E+08 7.51E+07 - - - 2.3946 1 221125_WJC_METTL3_EV_vs_WT_F10.06205.06205.2 6.72E-06 13/26 R.NYQQNYQNSESGEK[136.11].N "sp|P67809|YBOX1_HUMAN,tr|H0Y449|H0Y449_HUMAN,tr|C9J5V9|C9J5V9_HUMAN" 3 1695.7216 1.1 139546 6205 2 1695.72215 848.8681 Y-box-binding protein 1 OS=Homo sapiens OX=9606 GN=YBX1 PE=1 SV=3 4.53 1618.8 - 667093 - - - 0.3202 - 2.588 0.637 - 478.7 1 2 0 0.0005 14 0 0 0 9.65E+06 8.80E+06 - - - 6.1319 0.9999 221125_WJC_METTL3_EV_vs_WT_F10.06207.06207.3 1.59E-06 13/52 K.FGVSSESKPEEVKK.D sp|P49790|NU153_HUMAN 1 1549.7988 1.64 139547 6207 3 1549.803019 517.6069 Nuclear pore complex protein Nup153 OS=Homo sapiens OX=9606 GN=NUP153 PE=1 SV=2 6.23 1619.1 - 567969 - - - 2.73 - 2.591 0.479 - 127.3 1 2 0 0.0042 14 0 0 0 9.38E+07 5.72E+07 - - - 6.4093 0.9997 221125_WJC_METTL3_EV_vs_WT_F10.06208.06208.3 2.84E-05 Sep-44 K.HVQGWPADHAEK.Q "sp|Q9BTA9|WAC_HUMAN,tr|A0A7P0T961|A0A7P0T961_HUMAN,tr|A0A0A0MRT2|A0A0A0MRT2_HUMAN" 3 1373.6476 1.4 139548 6208 3 1373.650979 458.8898 WW domain-containing adapter protein with coiled-coil OS=Homo sapiens OX=9606 GN=WAC PE=1 SV=3 5.99 1619.2 - 344985 - - - 2.4257 - 2.016 0.397 - 91.3 1 2 0 0.0033 12 0 0 0 1.60E+07 1.14E+07 - - - 4.9086 0.9999 221125_WJC_METTL3_EV_vs_WT_F10.06211.06211.3 1.89E-06 Oct-56 K.NC[160.03]PTNGDK[136.11]NFESGPR[166.11].L "sp|Q7Z6E9|RBBP6_HUMAN,tr|H3BSK8|H3BSK8_HUMAN,tr|A0A2R8Y880|A0A2R8Y880_HUMAN,tr|H3BUN0|H3BUN0_HUMAN,tr|A0A087WY32|A0A087WY32_HUMAN" 5 1709.7547 0.27 139551 6211 3 1709.755022 570.9255 E3 ubiquitin-protein ligase RBBP6 OS=Homo sapiens OX=9606 GN=RBBP6 PE=1 SV=1 6.06 1619.6 - 126029 - - - 0.2164 - 2.018 0.57 - 114.6 1 2 1 0.0004 15 0 0 0 1.92E+06 7.18E+06 - - - 6.7269 0.8484 221125_WJC_METTL3_EV_vs_WT_F10.06213.06213.4 0.00074 13/72 K.GFRDDGLNNKPQR.D "sp|Q8IWI9|MGAP_HUMAN,tr|H3BP52|H3BP52_HUMAN" 2 1515.7542 0.07 139553 6213 4 1516.761151 379.9458 MAX gene-associated protein OS=Homo sapiens OX=9606 GN=MGA PE=1 SV=4 8.75 1619.9 - 104109 - - - 664.2983 - 1.978 0.345 - 159 1 2 1 1.0069 13 0 0 0 8.65E+04 1.16E+06 - - - 2.2029 1 221125_WJC_METTL3_EV_vs_WT_F10.06214.06214.2 3.76E-07 24-Oct R.FSSSSGYGGGSSR.V sp|P35527|K1C9_HUMAN 1 1234.5214 27.88 139554 6214 2 1234.523637 618.268 "Keratin, type I cytoskeletal 9 OS=Homo sapiens OX=9606 GN=KRT9 PE=1 SV=3" 8.75 1620 - 97790.7 - - - 1.7764 - 2.137 0.642 - 303.1 1 2 0 0.0022 13 0 0 0 1.47E+07 5.26E+05 - - - 5.7312 1 221125_WJC_METTL3_EV_vs_WT_F10.06221.06221.3 9.10E-07 17/52 K.FGVSSESK[136.11]PEEVK[136.11]K[136.11].D sp|P49790|NU153_HUMAN 1 1573.8414 1.64 139559 6221 3 1573.844887 525.6211 Nuclear pore complex protein Nup153 OS=Homo sapiens OX=9606 GN=NUP153 PE=1 SV=2 6.23 1621 - 1.22E+06 - - - 2.2232 - 3.275 0.527 - 268.1 1 2 0 0.0035 14 0 0 0 9.38E+07 5.72E+07 - - - 7.5672 0.9999 221125_WJC_METTL3_EV_vs_WT_F10.06223.06223.4 1.25E-07 15/78 K.FGVSSESK[136.11]PEEVK[136.11]K[136.11].D sp|P49790|NU153_HUMAN 1 1573.8414 1.5 139561 6223 4 1573.844993 394.4676 Nuclear pore complex protein Nup153 OS=Homo sapiens OX=9606 GN=NUP153 PE=1 SV=2 6.23 1621.2 - 1.99E+06 - - - 2.2906 - 2.608 0.472 - 92.3 1 2 0 0.0036 14 0 0 0 1.13E+08 7.51E+07 - - - 3.6822 0.9895 221125_WJC_METTL3_EV_vs_WT_F10.06233.06233.2 0.00197 20-Sep V.SSESK[136.11]PEEVK[136.11]K[136.11].D sp|P49790|NU153_HUMAN 1 1270.6831 1.51 139571 6233 2 1270.682966 636.3488 Nuclear pore complex protein Nup153 OS=Homo sapiens OX=9606 GN=NUP153 PE=1 SV=2 5.95 1622.4 - 50852.7 - - - -0.1023 - 1.98 0.454 - 190.8 1 1 0 -0.0001 11 0 0 0 3.55E+06 2.36E+06 - - - 4.2421 1 221125_WJC_METTL3_EV_vs_WT_F10.06236.06236.3 1.95E-08 14/60 K.ASAQDAGDHVQPPEGR.D sp|Q96BK5|PINX1_HUMAN 1 1633.7445 1.46 139573 6236 3 1633.747155 545.5888 PIN2\TERF1-interacting telomerase inhibitor 1 OS=Homo sapiens OX=9606 GN=PINX1 PE=1 SV=2 4.54 1622.8 - 613151 - - - 1.649 - 2.768 0.587 - 201.9 1 2 0 0.0027 16 0 0 0 1.73E+07 1.19E+07 - - - 7.6961 0.9912 221125_WJC_METTL3_EV_vs_WT_F10.06238.06238.3 0.000388 Nov-40 K.LLEQYK[136.11]EESK[136.11]K[136.11].A "sp|Q00839|HNRPU_HUMAN,tr|A0A1W2PQL0|A0A1W2PQL0_HUMAN,tr|A0A1W2PPL4|A0A1W2PPL4_HUMAN,tr|Q5RI18|Q5RI18_HUMAN,tr|A0A1W2PP35|A0A1W2PP35_HUMAN,tr|A0A1W2PPS1|A0A1W2PPS1_HUMAN,tr|A0A1W2PPH7|A0A1W2PPH7_HUMAN,tr|A0A1W2PQD4|A0A1W2PQD4_HUMAN,tr|A0A1W2PP34|A0A1W2PP34_HUMAN,tr|A0A1X7SBS1|A0A1X7SBS1_HUMAN" 10 1417.7879 1.3 139574 6238 3 1417.7944 473.6032 Heterogeneous nuclear ribonucleoprotein U OS=Homo sapiens OX=9606 GN=HNRNPU PE=1 SV=6 6.23 1623.1 - 2.27E+06 - - - 4.5874 - 2.207 0.358 - 185.8 1 2 1 0.0065 11 0 0 0 2.47E+08 1.90E+08 - - - 4.7784 0.9999 221125_WJC_METTL3_EV_vs_WT_F10.06242.06242.2 5.01E-05 13/26 K.K[136.11]GPGEVAGTVTGQK[136.11].R "sp|Q86U44|MTA70_HUMAN,tr|F5H6D8|F5H6D8_HUMAN,tr|H0YFV6|H0YFV6_HUMAN,tr|B4DTN4|B4DTN4_HUMAN" 4 1343.738 0.01 139578 6242 2 1343.739107 672.8763 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 8.59 1623.6 - 220341 - - - 0.8394 - 2.723 0.541 - 391 1 2 0 0.0011 14 0 0 0 2.33E+07 4.65E+09 - - - 5.5503 0.9989 221125_WJC_METTL3_EV_vs_WT_F10.06243.06243.3 0.000225 Sep-48 R.KLVDKEDIDTSSK.G "sp|P78332|RBM6_HUMAN,tr|C9J250|C9J250_HUMAN,tr|E9PGM9|E9PGM9_HUMAN" 3 1476.7672 1.07 139579 6243 3 1476.771512 493.263 RNA-binding protein 6 OS=Homo sapiens OX=9606 GN=RBM6 PE=1 SV=5 4.68 1623.7 - 213679 - - - 2.951 - 1.907 0.479 - 90.2 1 2 1 0.0044 13 0 0 0 1.79E+06 1.67E+06 - - - 5.6294 0.9904 221125_WJC_METTL3_EV_vs_WT_F10.06246.06246.2 0.000279 20-Nov V.SSESKPEEVKK.D sp|P49790|NU153_HUMAN 1 1246.6405 1.51 139582 6246 2 1246.640617 624.3275 Nuclear pore complex protein Nup153 OS=Homo sapiens OX=9606 GN=NUP153 PE=1 SV=2 5.95 1624.1 - 108667 - - - 0.0971 - 2.133 0.446 - 294.7 1 1 0 0.0001 11 0 0 0 3.55E+06 2.36E+06 - - - 4.3844 1 221125_WJC_METTL3_EV_vs_WT_F10.06247.06247.2 4.20E-08 28-Oct K.SQDVAVSPQQQQC[160.03]SK[136.11].S "sp|Q96F86|EDC3_HUMAN,tr|H3BPW9|H3BPW9_HUMAN,tr|H3BQ37|H3BQ37_HUMAN,tr|H3BTD6|H3BTD6_HUMAN" 4 1696.793 0.82 139583 6247 2 1696.799886 849.4038 Enhancer of mRNA-decapping protein 3 OS=Homo sapiens OX=9606 GN=EDC3 PE=1 SV=1 5.55 1624.2 - 74807.8 - - - 4.0594 - 2.447 0.652 - 372.4 1 2 0 0.0069 15 0 0 0 1.37E+06 1.68E+06 - - - 6.0546 0.9996 221125_WJC_METTL3_EV_vs_WT_F10.06252.06252.4 0.0154 Oct-78 K.YYLHDDREGEGSDK.W "sp|Q9Y2W1|TR150_HUMAN,tr|A0A3B3ITZ9|A0A3B3ITZ9_HUMAN" 2 1682.7172 3.03 139586 6252 4 1682.720081 421.6866 Thyroid hormone receptor-associated protein 3 OS=Homo sapiens OX=9606 GN=THRAP3 PE=1 SV=2 4.43 1624.9 - 1.00E+06 - - - 1.6866 - 1.623 0.45 - 52.6 1 2 1 0.0028 14 0 0 0 9.69E+08 3.20E+08 - - - 3.3183 0.9997 221125_WJC_METTL3_EV_vs_WT_F10.06254.06254.3 2.71E-05 Oct-52 K.YYLHDDREGEGSDK.W "sp|Q9Y2W1|TR150_HUMAN,tr|A0A3B3ITZ9|A0A3B3ITZ9_HUMAN" 2 1682.7172 2.96 139588 6254 3 1682.72124 561.913 Thyroid hormone receptor-associated protein 3 OS=Homo sapiens OX=9606 GN=THRAP3 PE=1 SV=2 4.43 1625.1 - 670232 - - - 2.3753 - 1.951 0.583 - 59.3 1 2 1 0.004 14 0 0 0 8.02E+08 2.70E+08 - - - 6.8149 0.9861 221125_WJC_METTL3_EV_vs_WT_F10.06255.06255.3 0.222 13/36 Q.HIVTIVHHVK[136.11].E "sp|Q9Y2W1|TR150_HUMAN,tr|A0A3B3ITZ9|A0A3B3ITZ9_HUMAN" 2 1189.7175 2.37 139589 6255 3 1189.717179 397.5798 Thyroid hormone receptor-associated protein 3 OS=Homo sapiens OX=9606 GN=THRAP3 PE=1 SV=2 8.77 1625.2 - 601673 - - - -0.2799 - 2.284 0.356 - 175.4 1 1 0 -0.0003 10 0 0 0 8.62E+07 3.63E+07 - - - 4.921 0.9958 221125_WJC_METTL3_EV_vs_WT_F10.06257.06257.4 0.0126 Oct-78 K.YYLHDDR[166.11]EGEGSDK[136.11].W "sp|Q9Y2W1|TR150_HUMAN,tr|A0A3B3ITZ9|A0A3B3ITZ9_HUMAN" 2 1700.7397 3.02 139591 6257 4 1700.740682 426.1922 Thyroid hormone receptor-associated protein 3 OS=Homo sapiens OX=9606 GN=THRAP3 PE=1 SV=2 4.43 1625.5 - 329501 - - - 0.5698 - 1.477 0.306 - 40.3 1 2 1 0.001 14 0 0 0 9.65E+08 3.19E+08 - - - 2.0311 0.963 221125_WJC_METTL3_EV_vs_WT_F10.06258.06258.2 0.267 20-Oct K.LLEQYKEESKK.A "sp|Q00839|HNRPU_HUMAN,tr|A0A1W2PQL0|A0A1W2PQL0_HUMAN,tr|A0A1W2PPL4|A0A1W2PPL4_HUMAN,tr|Q5RI18|Q5RI18_HUMAN,tr|A0A1W2PP35|A0A1W2PP35_HUMAN,tr|A0A1W2PPS1|A0A1W2PPS1_HUMAN,tr|A0A1W2PPH7|A0A1W2PPH7_HUMAN,tr|A0A1W2PQD4|A0A1W2PQD4_HUMAN,tr|A0A1W2PP34|A0A1W2PP34_HUMAN,tr|A0A1X7SBS1|A0A1X7SBS1_HUMAN" 10 1393.7453 1.07 139592 6258 2 1393.744464 697.8799 Heterogeneous nuclear ribonucleoprotein U OS=Homo sapiens OX=9606 GN=HNRNPU PE=1 SV=6 6.23 1625.6 - 212416 - - - -0.597 - 1.44 0.188 - 219.9 1 2 1 -0.0008 11 0 0 0 7.41E+06 6.96E+06 - - - 1.4158 0.9984 221125_WJC_METTL3_EV_vs_WT_F10.06259.06259.2 0.00819 20-Oct K.LLEQYK[136.11]EESK[136.11]K[136.11].A "sp|Q00839|HNRPU_HUMAN,tr|A0A1W2PQL0|A0A1W2PQL0_HUMAN,tr|A0A1W2PPL4|A0A1W2PPL4_HUMAN,tr|Q5RI18|Q5RI18_HUMAN,tr|A0A1W2PP35|A0A1W2PP35_HUMAN,tr|A0A1W2PPS1|A0A1W2PPS1_HUMAN,tr|A0A1W2PPH7|A0A1W2PPH7_HUMAN,tr|A0A1W2PQD4|A0A1W2PQD4_HUMAN,tr|A0A1W2PP34|A0A1W2PP34_HUMAN,tr|A0A1X7SBS1|A0A1X7SBS1_HUMAN" 10 1417.7879 1.06 139593 6259 2 1417.788865 709.9012 Heterogeneous nuclear ribonucleoprotein U OS=Homo sapiens OX=9606 GN=HNRNPU PE=1 SV=6 6.23 1625.7 - 176303 - - - 0.6835 - 2.25 0.482 - 300 1 2 1 0.001 11 0 0 0 7.39E+06 6.96E+06 - - - 4.7945 0.9999 221125_WJC_METTL3_EV_vs_WT_F10.06260.06260.4 9.43E-05 Nov-78 K.ISSTSVK[136.11]PK[136.11]PPPVR[166.11].A sp|Q9Y6W3|CAN7_HUMAN 1 1517.914 0.001 139594 6260 4 1517.915618 380.4858 Calpain-7 OS=Homo sapiens OX=9606 GN=CAPN7 PE=1 SV=1 11.17 1625.8 - 152344 - - - 1.0771 - 2.671 0.431 - 87.1 1 2 0 0.0016 14 0 0 0 0.00E+00 2.39E+06 - - - 3.3345 0.9999 221125_WJC_METTL3_EV_vs_WT_F10.06261.06261.3 0.000884 Nov-52 K.HGATLVHC[160.03]AAGVSR.S sp|O95147|DUS14_HUMAN 1 1434.715 999 139595 6261 3 1434.713969 479.2456 Dual specificity protein phosphatase 14 OS=Homo sapiens OX=9606 GN=DUSP14 PE=1 SV=1 8.27 1626 - 142904 - - - -0.7298 - 1.956 0.462 - 79.3 1 2 0 -0.001 14 0 0 0 3.42E+06 0.00E+00 - - - 5.4735 0.9995 221125_WJC_METTL3_EV_vs_WT_F10.06264.06264.2 0.00112 26-Jul K.FGVSSESKPEEVKK.D sp|P49790|NU153_HUMAN 1 1549.7988 2.11 139598 6264 2 1549.79838 775.9067 Nuclear pore complex protein Nup153 OS=Homo sapiens OX=9606 GN=NUP153 PE=1 SV=2 6.23 1626.4 - 78896 - - - -0.2633 - 1.372 0.425 - 99.1 1 2 0 -0.0004 14 0 0 0 1.33E+06 6.30E+05 - - - 2.9736 0.9997 221125_WJC_METTL3_EV_vs_WT_F10.06268.06268.3 0.000189 Dec-52 K.SNKDGGNQEVEIAR.C "sp|P13861|KAP2_HUMAN,tr|H7C330|H7C330_HUMAN" 2 1515.7277 1.92 139600 6268 3 1515.726435 506.2499 cAMP-dependent protein kinase type II-alpha regulatory subunit OS=Homo sapiens OX=9606 GN=PRKAR2A PE=1 SV=2 4.68 1626.9 - 971918 - - - -0.8663 - 2.313 0.445 - 174.5 1 2 1 -0.0013 14 0 0 0 6.90E+07 3.58E+07 - - - 5.7294 0.9997 221125_WJC_METTL3_EV_vs_WT_F10.06269.06269.3 1.12E-06 15/52 K.SNK[136.11]DGGNQEVEIAR[166.11].C "sp|P13861|KAP2_HUMAN,tr|H7C330|H7C330_HUMAN" 2 1533.7502 1.93 139601 6269 3 1533.75183 512.2573 cAMP-dependent protein kinase type II-alpha regulatory subunit OS=Homo sapiens OX=9606 GN=PRKAR2A PE=1 SV=2 4.68 1627 - 679317 - - - 1.051 - 2.426 0.445 - 388 1 2 1 0.0016 14 0 0 0 6.90E+07 3.58E+07 - - - 5.8561 0.9997 221125_WJC_METTL3_EV_vs_WT_F10.06278.06278.3 0.033 15/52 K.YYLHDDR[166.11]EGEGSDK[136.11].W "sp|Q9Y2W1|TR150_HUMAN,tr|A0A3B3ITZ9|A0A3B3ITZ9_HUMAN" 2 1700.7397 2.94 139608 6278 3 1700.737412 567.9205 Thyroid hormone receptor-associated protein 3 OS=Homo sapiens OX=9606 GN=THRAP3 PE=1 SV=2 4.43 1628.1 - 2.65E+06 - - - -1.3529 - 2.462 0.439 - 176.4 1 2 1 -0.0023 14 0 0 0 7.96E+08 2.70E+08 - - - 5.8281 0.9997 221125_WJC_METTL3_EV_vs_WT_F10.06281.06281.3 0.00157 Oct-40 R.YAHQSGFHVDR[166.11].R "sp|P41252|SYIC_HUMAN,tr|A0A804HL54|A0A804HL54_HUMAN,tr|A0A804HKU1|A0A804HKU1_HUMAN,tr|A0A804HK69|A0A804HK69_HUMAN,tr|A0A804HIV9|A0A804HIV9_HUMAN,tr|A0A804HKW6|A0A804HKW6_HUMAN,tr|A0A804HJN6|A0A804HJN6_HUMAN,tr|A0A804HHW9|A0A804HHW9_HUMAN,tr|A0A0A0MSX9|A0A0A0MSX9_HUMAN,tr|J3KR24|J3KR24_HUMAN,tr|A0A804HIG2|A0A804HIG2_HUMAN,tr|A0A804HJ36|A0A804HJ36_HUMAN" 12 1325.6141 7.55 139611 6281 3 1325.614205 442.8786 "Isoleucine--tRNA ligase, cytoplasmic OS=Homo sapiens OX=9606 GN=IARS1 PE=1 SV=2" 6.92 1628.5 - 412813 - - - 0.1147 - 1.68 0.376 - 100.4 1 2 0 0.0002 11 0 0 0 1.81E+08 2.40E+07 - - - 4.2058 0.7946 221125_WJC_METTL3_EV_vs_WT_F10.06285.06285.2 0.000864 18-Sep L.LEQYKEESKK.A "sp|Q00839|HNRPU_HUMAN,tr|A0A1W2PQL0|A0A1W2PQL0_HUMAN,tr|A0A1W2PPL4|A0A1W2PPL4_HUMAN,tr|Q5RI18|Q5RI18_HUMAN,tr|A0A1W2PP35|A0A1W2PP35_HUMAN,tr|A0A1W2PPS1|A0A1W2PPS1_HUMAN,tr|A0A1W2PPH7|A0A1W2PPH7_HUMAN,tr|A0A1W2PQD4|A0A1W2PQD4_HUMAN,tr|A0A1W2PP34|A0A1W2PP34_HUMAN,tr|A0A1X7SBS1|A0A1X7SBS1_HUMAN" 10 1280.6612 1.12 139613 6285 2 1280.662819 641.3379 Heterogeneous nuclear ribonucleoprotein U OS=Homo sapiens OX=9606 GN=HNRNPU PE=1 SV=6 6.23 1629 - 174981 - - - 1.2392 - 1.89 0.398 - 246.5 1 1 1 0.0016 10 0 0 0 2.72E+06 2.43E+06 - - - 3.757 1 221125_WJC_METTL3_EV_vs_WT_F10.06297.06297.2 5.19E-09 28-Oct A.GTNTGPNNSNTTFQK.R "sp|Q9NYF8|BCLF1_HUMAN,tr|H0YF14|H0YF14_HUMAN" 2 1579.7227 2.28 139623 6297 2 1579.719023 790.8686 Bcl-2-associated transcription factor 1 OS=Homo sapiens OX=9606 GN=BCLAF1 PE=1 SV=2 8.75 1630.4 - 173626 - - - -2.3042 - 2.187 0.648 - 310.2 1 1 0 -0.0036 15 0 0 0 6.87E+07 3.01E+07 - - - 5.7499 0.9946 221125_WJC_METTL3_EV_vs_WT_F10.06300.06300.2 8.37E-05 26-Jul K.YYLHDDR[166.11]EGEGSDK[136.11].W "sp|Q9Y2W1|TR150_HUMAN,tr|A0A3B3ITZ9|A0A3B3ITZ9_HUMAN" 2 1700.7397 2.95 139624 6300 2 1700.73567 851.3771 Thyroid hormone receptor-associated protein 3 OS=Homo sapiens OX=9606 GN=THRAP3 PE=1 SV=2 4.43 1630.8 - 214038 - - - -2.3772 - 1.759 0.522 - 109.1 1 2 1 -0.004 14 0 0 0 2.17E+07 7.36E+06 - - - 4.3124 0.9975 221125_WJC_METTL3_EV_vs_WT_F10.06305.06305.3 0.00046 18/36 Q.HIVTIVHHVK.E "sp|Q9Y2W1|TR150_HUMAN,tr|A0A3B3ITZ9|A0A3B3ITZ9_HUMAN" 2 1181.7033 2.37 139627 6305 3 1181.701311 394.9084 Thyroid hormone receptor-associated protein 3 OS=Homo sapiens OX=9606 GN=THRAP3 PE=1 SV=2 8.77 1631.5 - 2.07E+06 - - - -1.6933 - 2.99 0.508 - 469.8 1 1 0 -0.002 10 0 0 0 8.61E+07 3.63E+07 - - - 7.4018 0.9998 221125_WJC_METTL3_EV_vs_WT_F10.06307.06307.3 1.24E-07 13/60 K.STATESTKEEPQLESK.S "sp|Q86UP3|ZFHX4_HUMAN,tr|E7EVZ1|E7EVZ1_HUMAN" 2 1763.8425 1.48 139628 6307 3 1763.846354 588.9548 Zinc finger homeobox protein 4 OS=Homo sapiens OX=9606 GN=ZFHX4 PE=1 SV=1 4.49 1631.7 - 295678 - - - 2.1833 - 2.525 0.561 - 177.2 1 2 1 0.0039 16 0 0 0 1.24E+07 8.39E+06 - - - 7.1701 1 221125_WJC_METTL3_EV_vs_WT_F10.06315.06315.3 5.16E-05 16/44 K.RQEALPLHQETK.Q sp|Q86UP2|KTN1_HUMAN 1 1448.7736 1.56 139634 6315 3 1448.770966 483.9318 Kinectin OS=Homo sapiens OX=9606 GN=KTN1 PE=1 SV=1 6.76 1632.7 - 1.10E+06 - - - -1.8015 - 2.741 0.468 - 450.7 1 2 0 -0.0026 12 0 0 0 3.07E+07 1.97E+07 - - - 6.5519 1 221125_WJC_METTL3_EV_vs_WT_F10.06316.06316.3 0.000442 16/48 K.VQDQDLPNTPHSK.A sp|Q08554|DSC1_HUMAN 1 1477.7161 29.23 139635 6316 3 1477.715302 493.5793 Desmocollin-1 OS=Homo sapiens OX=9606 GN=DSC1 PE=1 SV=2 5.21 1632.8 - 920910 - - - -0.5542 - 2.744 0.476 - 450.8 1 2 0 -0.0008 13 0 0 0 1.82E+08 6.23E+06 - - - 6.5835 1 221125_WJC_METTL3_EV_vs_WT_F10.06317.06317.3 0.00505 16/44 K.R[166.11]QEALPLHQETK[136.11].Q sp|Q86UP2|KTN1_HUMAN 1 1466.796 1.56 139636 6317 3 1466.794748 489.9393 Kinectin OS=Homo sapiens OX=9606 GN=KTN1 PE=1 SV=1 6.76 1632.9 - 631903 - - - -0.8849 - 3.014 0.425 - 447.2 1 2 0 -0.0013 12 0 0 0 3.07E+07 1.97E+07 - - - 6.3361 1 221125_WJC_METTL3_EV_vs_WT_F10.06325.06325.3 5.26E-05 14/48 K.KIGEEEIQKPEEK.V sp|Q15459|SF3A1_HUMAN 1 1555.8094 0.76 139642 6325 3 1555.811997 519.6104 Splicing factor 3A subunit 1 OS=Homo sapiens OX=9606 GN=SF3A1 PE=1 SV=1 4.65 1634 - 573877 - - - 1.6994 - 2.353 0.543 - 209.7 1 2 0 0.0026 13 0 0 0 1.25E+07 1.65E+07 - - - 6.9132 1 221125_WJC_METTL3_EV_vs_WT_F10.06332.06332.3 0.0126 16/72 K.GEAAAERPGEAAVASSPSK.A sp|P29966|MARCS_HUMAN 1 1783.8701 1.17 139647 6332 3 1783.869354 595.6306 Myristoylated alanine-rich C-kinase substrate OS=Homo sapiens OX=9606 GN=MARCKS PE=1 SV=4 4.79 1634.9 - 757524 - - - -0.3935 - 3.189 0.481 - 326.5 1 2 0 -0.0007 19 0 0 0 2.72E+07 2.33E+07 - - - 6.7517 1 221125_WJC_METTL3_EV_vs_WT_F10.06333.06333.2 3.74E-07 16/20 L.HDDREGEGSDK.W "sp|Q9Y2W1|TR150_HUMAN,tr|A0A3B3ITZ9|A0A3B3ITZ9_HUMAN" 2 1243.5065 6.4 139648 6333 2 1243.504762 622.7605 Thyroid hormone receptor-associated protein 3 OS=Homo sapiens OX=9606 GN=THRAP3 PE=1 SV=2 4.43 1635 - 289786 - - - -1.4154 - 2.919 0.664 - 595.5 1 1 1 -0.0018 11 0 0 0 5.69E+06 8.89E+05 - - - 6.8427 1 221125_WJC_METTL3_EV_vs_WT_F10.06334.06334.3 3.80E-08 15/72 K.GEAAAER[166.11]PGEAAVASSPSK[136.11].A sp|P29966|MARCS_HUMAN 1 1801.8925 1.17 139649 6334 3 1801.888767 601.6381 Myristoylated alanine-rich C-kinase substrate OS=Homo sapiens OX=9606 GN=MARCKS PE=1 SV=4 4.79 1635.1 - 755714 - - - -2.0861 - 2.928 0.593 - 282.4 1 2 0 -0.0038 19 0 0 0 2.72E+07 2.33E+07 - - - 7.7897 1 221125_WJC_METTL3_EV_vs_WT_F10.06341.06341.3 7.25E-09 15/48 K.K[136.11]IGEEEIQK[136.11]PEEK[136.11].V sp|Q15459|SF3A1_HUMAN 1 1579.852 0.76 139654 6341 3 1579.850951 527.6246 Splicing factor 3A subunit 1 OS=Homo sapiens OX=9606 GN=SF3A1 PE=1 SV=1 4.65 1636 - 557192 - - - -0.6342 - 3.29 0.518 - 245.4 1 2 0 -0.001 13 0 0 0 1.25E+07 1.65E+07 - - - 7.5438 0.9915 221125_WJC_METTL3_EV_vs_WT_F10.06343.06343.2 0.00513 18-Sep K.EEIDREFHNK.L "sp|Q8ND56|LS14A_HUMAN,tr|A0A140TA76|A0A140TA76_HUMAN,tr|K7EMZ9|K7EMZ9_HUMAN" 3 1315.6157 1.12 139656 6343 2 1315.615433 658.8151 Protein LSM14 homolog A OS=Homo sapiens OX=9606 GN=LSM14A PE=1 SV=3 4.83 1636.3 - 145400 - - - -0.187 - 1.794 0.262 - 287.6 1 2 1 -0.0002 10 0 0 0 3.89E+07 3.48E+07 - - - 2.6074 0.9871 221125_WJC_METTL3_EV_vs_WT_F10.06346.06346.4 0.101 Sep-78 K.SLEEKNESLTEHPR.S "sp|Q99590|SCAFB_HUMAN,tr|F8VXG7|F8VXG7_HUMAN,tr|A0A0A0MTP7|A0A0A0MTP7_HUMAN" 3 1667.8115 0.61 139657 6346 4 1667.811823 417.9601 Protein SCAF11 OS=Homo sapiens OX=9606 GN=SCAF11 PE=1 SV=2 4.9 1636.7 - 406302 - - - 0.2069 - 1.736 0.247 - 51 1 2 1 0.0003 14 0 0 0 9.20E+06 1.51E+07 - - - 1.5765 0.9994 221125_WJC_METTL3_EV_vs_WT_F10.06347.06347.3 0.0002 Nov-52 K.SLEEKNESLTEHPR.S "sp|Q99590|SCAFB_HUMAN,tr|F8VXG7|F8VXG7_HUMAN,tr|A0A0A0MTP7|A0A0A0MTP7_HUMAN" 3 1667.8115 1.01 139658 6347 3 1667.81318 556.9444 Protein SCAF11 OS=Homo sapiens OX=9606 GN=SCAF11 PE=1 SV=2 4.9 1636.8 - 237421 - - - 1.0205 - 1.962 0.425 - 115.8 1 2 1 0.0017 14 0 0 0 7.80E+06 7.75E+06 - - - 5.0689 0.9999 221125_WJC_METTL3_EV_vs_WT_F10.06348.06348.3 0.00118 Dec-68 K.AEGPSSTPSSAAGPRPPR.L "sp|Q9UK33|ZN580_HUMAN,tr|K7ENY2|K7ENY2_HUMAN,tr|K7ERU0|K7ERU0_HUMAN" 3 1720.8493 1.53 139659 6348 3 1720.848108 574.6237 Zinc finger protein 580 OS=Homo sapiens OX=9606 GN=ZNF580 PE=1 SV=1 9.64 1637 - 418389 - - - -0.6694 - 2.447 0.405 - 157.5 1 2 0 -0.0012 18 0 0 0 2.57E+07 1.68E+07 - - - 5.2833 0.9966 221125_WJC_METTL3_EV_vs_WT_F10.06349.06349.2 0.0175 18-Oct K.EEIDR[166.11]EFHNK[136.11].L "sp|Q8ND56|LS14A_HUMAN,tr|A0A140TA76|A0A140TA76_HUMAN,tr|K7EMZ9|K7EMZ9_HUMAN" 3 1333.6381 1.12 139660 6349 2 1333.637515 667.8264 Protein LSM14 homolog A OS=Homo sapiens OX=9606 GN=LSM14A PE=1 SV=3 4.83 1637.1 - 389935 - - - -0.4754 - 2.03 0.347 - 354.1 1 2 1 -0.0006 10 0 0 0 3.89E+07 3.48E+07 - - - 3.5801 0.9549 221125_WJC_METTL3_EV_vs_WT_F10.06353.06353.3 0.614 Nov-36 K.EEIDREFHNK.L "sp|Q8ND56|LS14A_HUMAN,tr|A0A140TA76|A0A140TA76_HUMAN,tr|K7EMZ9|K7EMZ9_HUMAN" 3 1315.6157 1.23 139662 6353 3 1315.615779 439.5458 Protein LSM14 homolog A OS=Homo sapiens OX=9606 GN=LSM14A PE=1 SV=3 4.83 1637.6 - 7.05E+06 - - - 0.076 - 1.835 0.133 - 179.6 1 2 1 0.0001 10 0 0 0 6.02E+08 4.88E+08 - - - 1.7956 0.9442 221125_WJC_METTL3_EV_vs_WT_F10.06354.06354.3 0.124 Aug-48 K.LK[136.11]EDK[136.11]APQVDVDK[136.11].A "sp|P41250|GARS_HUMAN,tr|H7C443|H7C443_HUMAN,tr|A0A6Q8PGI6|A0A6Q8PGI6_HUMAN,tr|A0A6Q8PGA8|A0A6Q8PGA8_HUMAN,tr|A0A6Q8PGZ8|A0A6Q8PGZ8_HUMAN,tr|A0A6Q8PFU7|A0A6Q8PFU7_HUMAN,tr|A0A6Q8PH49|A0A6Q8PH49_HUMAN,tr|A0A6Q8PGT3|A0A6Q8PGT3_HUMAN,tr|A0A6Q8PF45|A0A6Q8PF45_HUMAN,tr|A0A6Q8PFV5|A0A6Q8PFV5_HUMAN,tr|A0A6Q8PGN7|A0A6Q8PGN7_HUMAN,tr|A0A6Q8PGZ9|A0A6Q8PGZ9_HUMAN,tr|A0A6Q8PHI7|A0A6Q8PHI7_HUMAN,tr|A0A6Q8PFZ6|A0A6Q8PFZ6_HUMAN,tr|F8WCK4|F8WCK4_HUMAN" 15 1507.8308 0.75 139663 6354 3 1507.832004 503.6176 Glycine--tRNA ligase OS=Homo sapiens OX=9606 GN=GARS1 PE=1 SV=3 4.68 1637.8 - 464465 - - - 0.7832 - 1.537 0.176 - 41.8 1 2 2 0.0012 13 0 0 0 7.33E+06 9.84E+06 - - - 1.6673 0.9998 221125_WJC_METTL3_EV_vs_WT_F10.06358.06358.2 3.28E-05 24-Aug K.VQDQDLPNTPHSK.A sp|Q08554|DSC1_HUMAN 1 1477.7161 999 139667 6358 2 1477.713674 739.8653 Desmocollin-1 OS=Homo sapiens OX=9606 GN=DSC1 PE=1 SV=2 5.21 1638.3 - 126594 - - - -1.6559 - 1.82 0.539 - 195.5 1 2 0 -0.0024 13 0 0 0 6.48E+06 0.00E+00 - - - 4.5582 1 221125_WJC_METTL3_EV_vs_WT_F10.06362.06362.3 1.81E-07 15/52 R.K[136.11]PSVSEEVQATPNK[136.11].A sp|Q9UKJ3|GPTC8_HUMAN 1 1528.8068 1.22 139669 6362 3 1528.80689 510.6095 G patch domain-containing protein 8 OS=Homo sapiens OX=9606 GN=GPATCH8 PE=1 SV=2 6.14 1638.8 - 312485 - - - 0.0674 - 2.791 0.493 - 371.9 1 2 0 0.0001 14 0 0 0 3.67E+07 3.00E+07 - - - 6.7641 0.9999 221125_WJC_METTL3_EV_vs_WT_F10.06363.06363.3 0.00122 16/36 K.NKYEDEINKR.T "sp|P48668|K2C6C_HUMAN,sp|P05787|K2C8_HUMAN,sp|P04264|K2C1_HUMAN,sp|P04259|K2C6B_HUMAN,sp|P13647|K2C5_HUMAN,sp|P02538|K2C6A_HUMAN,tr|F8VUG2|F8VUG2_HUMAN,tr|F8W0C6|F8W0C6_HUMAN,tr|F8VP67|F8VP67_HUMAN,tr|F8W1U3|F8W1U3_HUMAN" 10 1307.647 999 139670 6363 3 1307.647722 436.8896 "Keratin, type II cytoskeletal 6C OS=Homo sapiens OX=9606 GN=KRT6C PE=1 SV=3" 6.18 1638.9 - 1.22E+06 - - - 0.5682 - 2.687 0.474 - 493.8 1 2 1 0.0007 10 0 0 0 2.63E+07 0.00E+00 - - - 6.7111 1 221125_WJC_METTL3_EV_vs_WT_F10.06368.06368.2 4.17E-12 14/28 A.GTNTGPNNSNTTFQK[136.11].R "sp|Q9NYF8|BCLF1_HUMAN,tr|H0YF14|H0YF14_HUMAN" 2 1587.7369 2.28 139673 6368 2 1587.735525 794.8757 Bcl-2-associated transcription factor 1 OS=Homo sapiens OX=9606 GN=BCLAF1 PE=1 SV=2 8.75 1639.5 - 1.02E+06 - - - -0.8427 - 3.124 0.595 - 837.4 1 1 0 -0.0013 15 0 0 0 6.87E+07 3.01E+07 - - - 6.2358 1 221125_WJC_METTL3_EV_vs_WT_F10.06381.06381.3 7.94E-07 14/52 R.KPSVSEEVQATPNK.A sp|Q9UKJ3|GPTC8_HUMAN 1 1512.7784 1.21 139682 6381 3 1512.78123 505.2667 G patch domain-containing protein 8 OS=Homo sapiens OX=9606 GN=GPATCH8 PE=1 SV=2 6.14 1641.2 - 569052 - - - 1.8793 - 2.671 0.515 - 322 1 2 0 0.0028 14 0 0 0 2.78E+07 2.30E+07 - - - 6.8919 0.9996 221125_WJC_METTL3_EV_vs_WT_F10.06387.06387.3 2.41E-05 Sep-64 R.IISSIEQKEENKGGEDK.L "sp|P62258|1433E_HUMAN,tr|B4DJF2|B4DJF2_HUMAN,tr|I3L3T1|I3L3T1_HUMAN,tr|K7EIT4|K7EIT4_HUMAN" 4 1902.9535 1.42 139688 6387 3 1902.955901 635.3251 14-3-3 protein epsilon OS=Homo sapiens OX=9606 GN=YWHAE PE=1 SV=1 4.59 1642 - 211794 - - - 1.2875 - 1.932 0.477 - 59.8 1 2 2 0.0024 17 0 0 0 6.51E+06 4.58E+06 - - - 5.5211 0.9937 221125_WJC_METTL3_EV_vs_WT_F10.06390.06390.3 0.00619 Sep-48 K.SREDLSAQPVQTK.F "sp|Q07157|ZO1_HUMAN,tr|A0A087X0K9|A0A087X0K9_HUMAN,tr|G5E9E7|G5E9E7_HUMAN,tr|A0A0G2JNH2|A0A0G2JNH2_HUMAN,tr|G3V1L9|G3V1L9_HUMAN,tr|A0A7I2V5U5|A0A7I2V5U5_HUMAN" 6 1457.7474 1.15 139691 6390 3 1457.746666 486.9231 Tight junction protein ZO-1 OS=Homo sapiens OX=9606 GN=TJP1 PE=1 SV=3 5.79 1642.3 - 126920 - - - -0.5179 - 1.784 0.267 - 99.1 1 2 1 -0.0008 13 0 0 0 3.88E+06 3.38E+06 - - - 3.086 1 221125_WJC_METTL3_EV_vs_WT_F10.06392.06392.3 1.70E-08 13/52 K.K[136.11]GPGEVAGTVTGQK[136.11].R "sp|Q86U44|MTA70_HUMAN,tr|F5H6D8|F5H6D8_HUMAN,tr|H0YFV6|H0YFV6_HUMAN,tr|B4DTN4|B4DTN4_HUMAN" 4 1343.738 0.02 139692 6392 3 1343.737249 448.9199 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 8.59 1642.6 - 5.77E+07 - - - -0.5433 - 2.95 0.592 - 325.4 1 2 0 -0.0007 14 0 0 0 2.13E+08 1.28E+10 - - - 8.0149 0.9999 221125_WJC_METTL3_EV_vs_WT_F10.06396.06396.4 8.67E-05 15/72 R.QDPQLHPEDPERR.A "sp|Q13084|RM28_HUMAN,tr|A2IDC6|A2IDC6_HUMAN,tr|A2IDC7|A2IDC7_HUMAN,tr|Q4TT37|Q4TT37_HUMAN" 4 1615.7703 1.7 139696 6396 4 1615.769555 404.9498 "39S ribosomal protein L28, mitochondrial OS=Homo sapiens OX=9606 GN=MRPL28 PE=1 SV=4" 4.75 1643 - 383816 - - - -0.4499 - 2.354 0.437 - 131.7 1 2 0 -0.0007 13 0 0 0 2.62E+07 1.54E+07 - - - 3.3469 0.895 221125_WJC_METTL3_EV_vs_WT_F10.06409.06409.3 0.219 Nov-64 R.IISSIEQK[136.11]EENK[136.11]GGEDK[136.11].L "sp|P62258|1433E_HUMAN,tr|B4DJF2|B4DJF2_HUMAN,tr|I3L3T1|I3L3T1_HUMAN,tr|K7EIT4|K7EIT4_HUMAN" 4 1926.9961 1.42 139705 6409 3 1926.993955 643.3393 14-3-3 protein epsilon OS=Homo sapiens OX=9606 GN=YWHAE PE=1 SV=1 4.59 1644.6 - 373614 - - - -1.0877 - 1.524 0.151 - 85.3 1 2 2 -0.0021 17 0 0 0 6.51E+06 4.58E+06 - - - 1.2873 0.9999 221125_WJC_METTL3_EV_vs_WT_F10.06412.06412.3 0.000137 Oct-60 R.ETGTEHSPGVQPADVK.E "sp|Q9H7C9|AAMDC_HUMAN,tr|K4DI89|K4DI89_HUMAN,tr|E9PLK9|E9PLK9_HUMAN,tr|E9PNP3|E9PNP3_HUMAN,tr|E9PJP1|E9PJP1_HUMAN" 5 1650.7849 1.9 139706 6412 3 1650.782314 551.2689 Mth938 domain-containing protein OS=Homo sapiens OX=9606 GN=AAMDC PE=1 SV=1 4.65 1645 - 1.81E+06 - - - -1.5841 - 1.909 0.458 - 100.5 1 2 0 -0.0026 16 0 0 0 7.69E+07 4.06E+07 - - - 5.3046 0.9995 221125_WJC_METTL3_EV_vs_WT_F10.06419.06419.3 0.0239 Nov-60 R.ETGTEHSPGVQPADVK[136.11].E "sp|Q9H7C9|AAMDC_HUMAN,tr|K4DI89|K4DI89_HUMAN,tr|E9PLK9|E9PLK9_HUMAN,tr|E9PNP3|E9PNP3_HUMAN,tr|E9PJP1|E9PJP1_HUMAN" 5 1658.7991 1.89 139710 6419 3 1658.79902 553.9403 Mth938 domain-containing protein OS=Homo sapiens OX=9606 GN=AAMDC PE=1 SV=1 4.65 1645.9 - 999792 - - - -0.0657 - 1.68 0.348 - 119.4 1 2 0 -0.0001 16 0 0 0 7.69E+07 4.06E+07 - - - 3.751 0.9998 221125_WJC_METTL3_EV_vs_WT_F10.06420.06420.2 1.06E-06 16/26 K.KGPGEVAGTVTGQK[136.11].R "sp|Q86U44|MTA70_HUMAN,tr|F5H6D8|F5H6D8_HUMAN,tr|H0YFV6|H0YFV6_HUMAN,tr|B4DTN4|B4DTN4_HUMAN" 4 1335.7238 - 139711 6420 2 1335.721416 668.8692 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 8.59 1646.1 - 812693 - - - -1.7691 - 2.859 0.543 - 477.1 1 2 0 -0.0024 14 0 0 0 - - - - - 5.687 0.9987 221125_WJC_METTL3_EV_vs_WT_F10.06425.06425.3 0.00296 Aug-56 R.IHTGEK[136.11]PYVC[160.03]PDC[160.03]GK[136.11].A sp|Q9BWE0|REPI1_HUMAN 1 1775.8306 1.05 139714 6425 3 1775.83413 592.9508 Replication initiator 1 OS=Homo sapiens OX=9606 GN=REPIN1 PE=1 SV=1 6.73 1646.7 - 194908 - - - 2.0013 - 1.523 0.355 - 66.2 1 2 0 0.0036 15 0 0 0 7.42E+06 7.10E+06 - - - 3.5946 1 221125_WJC_METTL3_EV_vs_WT_F10.06426.06426.3 2.45E-05 Dec-48 R.QDPQLHPEDPER[166.11]R[166.11].A "sp|Q13084|RM28_HUMAN,tr|A2IDC6|A2IDC6_HUMAN,tr|A2IDC7|A2IDC7_HUMAN,tr|Q4TT37|Q4TT37_HUMAN" 4 1635.7868 1.9 139715 6426 3 1635.785742 546.2696 "39S ribosomal protein L28, mitochondrial OS=Homo sapiens OX=9606 GN=MRPL28 PE=1 SV=4" 4.75 1646.8 - 290566 - - - -0.6602 - 2.38 0.5 - 173.8 1 2 0 -0.0011 13 0 0 0 1.63E+07 8.60E+06 - - - 6.4652 1 221125_WJC_METTL3_EV_vs_WT_F10.06431.06431.3 1.04E-05 15/36 R.K[136.11]QDSGHLDLR[166.11].N "sp|Q86U44|MTA70_HUMAN,tr|B4E349|B4E349_HUMAN,tr|F5H6D8|F5H6D8_HUMAN,tr|B4DTN4|B4DTN4_HUMAN" 4 1185.6221 0.11 139717 6431 3 1185.620463 396.2146 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 6.75 1647.5 - 1.56E+06 - - - -1.3849 - 2.516 0.52 - 297.3 1 2 0 -0.0016 10 0 0 0 5.98E+06 5.33E+07 - - - 7.0316 0.9999 221125_WJC_METTL3_EV_vs_WT_F10.06432.06432.3 2.04E-08 16/44 K.KLNVTEQEKIDK.L "sp|P06733|ENOA_HUMAN,tr|A0A2R8Y6G6|A0A2R8Y6G6_HUMAN,tr|K7EM90|K7EM90_HUMAN,tr|A0A2R8Y879|A0A2R8Y879_HUMAN,tr|A0A2R8YEM5|A0A2R8YEM5_HUMAN" 5 1443.7933 1.55 139718 6432 3 1443.791425 482.2717 Alpha-enolase OS=Homo sapiens OX=9606 GN=ENO1 PE=1 SV=2 6.18 1647.6 - 1.05E+06 - - - -1.3049 - 3.302 0.563 - 319.7 1 2 1 -0.0019 12 0 0 0 2.79E+08 1.80E+08 - - - 8.1274 1 221125_WJC_METTL3_EV_vs_WT_F10.06433.06433.3 2.44E-06 19/44 K.K[136.11]LNVTEQEK[136.11]IDK[136.11].L "sp|P06733|ENOA_HUMAN,tr|A0A2R8Y6G6|A0A2R8Y6G6_HUMAN,tr|K7EM90|K7EM90_HUMAN,tr|A0A2R8Y879|A0A2R8Y879_HUMAN,tr|A0A2R8YEM5|A0A2R8YEM5_HUMAN" 5 1467.8359 1.55 139719 6433 3 1467.834499 490.2859 Alpha-enolase OS=Homo sapiens OX=9606 GN=ENO1 PE=1 SV=2 6.18 1647.8 - 1.33E+06 - - - -0.9606 - 3.663 0.582 - 454.8 1 2 1 -0.0014 12 0 0 0 2.78E+08 1.80E+08 - - - 8.627 1 221125_WJC_METTL3_EV_vs_WT_F10.06434.06434.3 7.32E-07 17/56 K.SNIHC[160.03]NTIAPNAGSR.M "sp|P51659|DHB4_HUMAN,tr|A0A2R8Y7L2|A0A2R8Y7L2_HUMAN,tr|A0A2R8YD50|A0A2R8YD50_HUMAN,tr|E7ET17|E7ET17_HUMAN,tr|E7ER27|E7ER27_HUMAN,tr|E7EPL9|E7EPL9_HUMAN,tr|A0A804HKU2|A0A804HKU2_HUMAN,tr|A0A804HIG8|A0A804HIG8_HUMAN,tr|A0A2R8Y7W2|A0A2R8Y7W2_HUMAN,tr|A0A804HK65|A0A804HK65_HUMAN" 10 1610.7583 0.7 139720 6434 3 1610.756292 537.9267 Peroxisomal multifunctional enzyme type 2 OS=Homo sapiens OX=9606 GN=HSD17B4 PE=1 SV=3 7.99 1647.9 - 721776 - - - -1.2696 - 3.274 0.594 - 386.2 1 2 0 -0.002 15 0 0 0 2.52E+07 3.61E+07 - - - 8.2567 0.9983 221125_WJC_METTL3_EV_vs_WT_F10.06437.06437.3 0.0116 16/60 S.VSVSTSHTTISGGGSR.G sp|P04264|K2C1_HUMAN 1 1531.759 464.34 139721 6437 3 1531.758166 511.5936 "Keratin, type II cytoskeletal 1 OS=Homo sapiens OX=9606 GN=KRT1 PE=1 SV=6" 9.73 1648.3 - 941846 - - - -0.5758 - 3.048 0.539 - 441.7 1 1 0 -0.0009 16 0 0 0 4.85E+07 1.04E+05 - - - 7.4087 0.9888 221125_WJC_METTL3_EV_vs_WT_F10.06443.06443.3 0.022 Jun-52 R.GDQC[160.03]C[160.03]YSHSPPTPR[166.11].V sp|Q9NXH9|TRM1_HUMAN 1 1670.6805 0.31 139724 6443 3 1670.683733 557.9008 tRNA (guanine(26)-N(2))-dimethyltransferase OS=Homo sapiens OX=9606 GN=TRMT1 PE=1 SV=1 6.73 1649 - 253796 - - - 1.9381 - 1.152 0.287 - 38.8 1 2 0 0.0032 14 0 0 0 2.04E+06 6.61E+06 - - - 2.1149 0.9447 221125_WJC_METTL3_EV_vs_WT_F10.06445.06445.3 0.0294 Aug-36 K.KRAEFTVETR.S "sp|P21333|FLNA_HUMAN,tr|A0A7P0NMY4|A0A7P0NMY4_HUMAN,tr|Q60FE5|Q60FE5_HUMAN,tr|A0A7I2V3E6|A0A7I2V3E6_HUMAN,tr|A0A087WWY3|A0A087WWY3_HUMAN,tr|F8WE98|F8WE98_HUMAN" 6 1235.6622 0.71 139725 6445 3 1235.659697 412.8947 Filamin-A OS=Homo sapiens OX=9606 GN=FLNA PE=1 SV=4 8.75 1649.2 - 465621 - - - -2.054 - 1.43 0.221 - 70.5 1 2 1 -0.0025 10 0 0 0 1.95E+07 2.76E+07 - - - 2.0478 0.9997 221125_WJC_METTL3_EV_vs_WT_F10.06447.06447.3 0.000977 Nov-52 K.K[136.11]GPGEVAGTVTGQK.R "sp|Q86U44|MTA70_HUMAN,tr|F5H6D8|F5H6D8_HUMAN,tr|H0YFV6|H0YFV6_HUMAN,tr|B4DTN4|B4DTN4_HUMAN" 4 1335.7238 - 139727 6447 3 1335.724001 446.2485 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 8.59 1649.4 - 4.18E+06 - - - 0.1662 - 2.184 0.319 - 166 1 2 0 0.0002 14 0 0 0 - - - - - 4.1724 1 221125_WJC_METTL3_EV_vs_WT_F10.06453.06453.2 7.73E-08 15/20 K.AEEDKLEQIKK.W sp|P13674|P4HA1_HUMAN 1 1329.714 1.53 139731 6453 2 1329.708255 665.8643 Prolyl 4-hydroxylase subunit alpha-1 OS=Homo sapiens OX=9606 GN=P4HA1 PE=1 SV=2 4.87 1650.1 - 366788 - - - -4.3175 - 2.879 0.55 - 628.1 1 2 1 -0.0057 11 0 0 0 2.24E+07 1.46E+07 - - - 5.9621 0.9999 221125_WJC_METTL3_EV_vs_WT_F10.06455.06455.3 2.76E-08 13/40 R.RGDDSFGDKYR.D "sp|P23588|IF4B_HUMAN,tr|E7EX17|E7EX17_HUMAN" 2 1314.5953 2.62 139733 6455 3 1314.595341 439.2057 Eukaryotic translation initiation factor 4B OS=Homo sapiens OX=9606 GN=EIF4B PE=1 SV=2 6.04 1650.2 - 7.64E+06 - - - 0.0487 - 2.686 0.601 - 254 1 2 1 0.0001 11 0 0 0 2.25E+08 8.59E+07 - - - 8.0474 0.9787 221125_WJC_METTL3_EV_vs_WT_F10.06457.06457.2 0.0492 20-Jun R.RGDDSFGDKYR.D "sp|P23588|IF4B_HUMAN,tr|E7EX17|E7EX17_HUMAN" 2 1314.5953 4.51 139735 6457 2 1314.597125 658.3049 Eukaryotic translation initiation factor 4B OS=Homo sapiens OX=9606 GN=EIF4B PE=1 SV=2 6.04 1650.5 - 322456 - - - 1.4058 - 1.222 0.357 - 64.8 1 2 1 0.0018 11 0 0 0 6.40E+06 1.42E+06 - - - 2.2196 0.9759 221125_WJC_METTL3_EV_vs_WT_F10.06462.06462.3 0.000963 Aug-40 K.AEEDK[136.11]LEQIK[136.11]K[136.11].W sp|P13674|P4HA1_HUMAN 1 1353.7566 1.83 139738 6462 3 1353.751624 452.2595 Prolyl 4-hydroxylase subunit alpha-1 OS=Homo sapiens OX=9606 GN=P4HA1 PE=1 SV=2 4.87 1651.2 - 8.42E+06 - - - -3.6727 - 1.618 0.314 - 60.8 1 2 1 -0.005 11 0 0 0 3.66E+08 2.00E+08 - - - 3.4064 0.9998 221125_WJC_METTL3_EV_vs_WT_F10.06466.06466.3 8.93E-09 16/48 R.K[136.11]AVVVC[160.03]PK[136.11]DEDYK[136.11].Q "sp|Q00839|HNRPU_HUMAN,tr|A0A1W2PQL0|A0A1W2PQL0_HUMAN,tr|A0A1W2PPL4|A0A1W2PPL4_HUMAN,tr|A0A1W2PQ74|A0A1W2PQ74_HUMAN,tr|Q5RI18|Q5RI18_HUMAN,tr|A0A1W2PP35|A0A1W2PP35_HUMAN,tr|A0A1W2PPS1|A0A1W2PPS1_HUMAN,tr|A0A1W2PRZ7|A0A1W2PRZ7_HUMAN,tr|A0A1W2PPH7|A0A1W2PPH7_HUMAN,tr|A0A1W2PQD4|A0A1W2PQD4_HUMAN,tr|A0A1W2PP34|A0A1W2PP34_HUMAN,tr|A0A1X7SBS1|A0A1X7SBS1_HUMAN" 12 1573.8236 0.94 139740 6466 3 1573.823239 525.6152 Heterogeneous nuclear ribonucleoprotein U OS=Homo sapiens OX=9606 GN=HNRNPU PE=1 SV=6 6.11 1651.6 - 425722 - - - -0.2484 - 2.628 0.461 - 300.6 1 2 1 -0.0004 13 0 0 0 2.85E+08 3.02E+08 - - - 6.2993 0.9931 221125_WJC_METTL3_EV_vs_WT_F10.06469.06469.2 0.000188 22-Nov K.KLNVTEQEKIDK.L "sp|P06733|ENOA_HUMAN,tr|A0A2R8Y6G6|A0A2R8Y6G6_HUMAN,tr|K7EM90|K7EM90_HUMAN,tr|A0A2R8Y879|A0A2R8Y879_HUMAN,tr|A0A2R8YEM5|A0A2R8YEM5_HUMAN" 5 1443.7933 1.98 139743 6469 2 1443.788425 722.9039 Alpha-enolase OS=Homo sapiens OX=9606 GN=ENO1 PE=1 SV=2 6.18 1652 - 367310 - - - -3.3828 - 2.626 0.481 - 335 1 2 1 -0.0049 12 0 0 0 8.24E+06 4.15E+06 - - - 5.1324 0.9959 221125_WJC_METTL3_EV_vs_WT_F10.06472.06472.3 1.37 Aug-56 R.IHTGEKPYVC[160.03]PDC[160.03]GK.A sp|Q9BWE0|REPI1_HUMAN 1 1759.8022 1.02 139744 6472 3 1759.801791 587.608 Replication initiator 1 OS=Homo sapiens OX=9606 GN=REPIN1 PE=1 SV=1 6.73 1652.4 - 244157 - - - -0.2188 - 1.611 0.231 - 83.2 1 2 0 -0.0004 15 0 0 0 7.65E+06 7.49E+06 - - - 2.3596 1 221125_WJC_METTL3_EV_vs_WT_F10.06473.06473.2 2.17E-06 28-Sep R.NTDQASMPDNTAAQK.V "sp|P35749|MYH11_HUMAN,sp|P35579|MYH9_HUMAN,tr|A0A494C024|A0A494C024_HUMAN" 3 1590.6944 0.96 139745 6473 2 1590.693377 796.3545 Myosin-11 OS=Homo sapiens OX=9606 GN=MYH11 PE=1 SV=3 4.21 1652.5 - 239577 - - - -0.6425 - 1.961 0.692 - 206.9 1 2 0 -0.001 15 0 0 0 6.57E+06 6.82E+06 - - - 5.8075 0.9902 221125_WJC_METTL3_EV_vs_WT_F10.06474.06474.3 0.00713 Nov-56 R.ALQHSYLHK[136.11]DEGNPE.- "sp|P11802|CDK4_HUMAN,tr|F8VZ13|F8VZ13_HUMAN" 2 1744.826 0.47 139746 6474 3 1744.823152 582.6159 Cyclin-dependent kinase 4 OS=Homo sapiens OX=9606 GN=CDK4 PE=1 SV=2 5.4 1652.6 - 794885 - - - -1.6391 - 1.937 0.247 - 95.4 1 2 1 -0.0029 15 0 0 0 1.93E+07 4.12E+07 - - - 3.0182 0.9994 221125_WJC_METTL3_EV_vs_WT_F10.06477.06477.3 0.00137 Sep-52 K.K[136.11]VEAPETNIDK[136.11]TPK[136.11].K "sp|O75152|ZC11A_HUMAN,tr|E9PBY7|E9PBY7_HUMAN,tr|E9PQ61|E9PQ61_HUMAN" 3 1592.8836 1.12 139749 6477 3 1592.880189 531.9685 Zinc finger CCCH domain-containing protein 11A OS=Homo sapiens OX=9606 GN=ZC3H11A PE=1 SV=3 6.18 1653 - 327860 - - - -2.1332 - 1.897 0.485 - 51.6 1 2 1 -0.0034 14 0 0 0 8.94E+06 7.99E+06 - - - 5.6479 0.9997 221125_WJC_METTL3_EV_vs_WT_F10.06481.06481.2 0.000563 14-Sep K.EHC[160.03]LVGVK[136.11].G sp|Q86U44|MTA70_HUMAN 1 948.4942 0 139751 6481 2 948.492742 475.2544 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 6.83 1653.6 - 4.12E+06 - - - -1.5762 - 1.615 0.488 - 413.8 1 2 0 -0.0015 8 0 0 0 5.34E+05 1.44E+08 - - - 4.0906 0.9804 221125_WJC_METTL3_EV_vs_WT_F10.06483.06483.3 0.0545 Oct-36 K.K[136.11]R[166.11]AEFTVETR[166.11].S "sp|P21333|FLNA_HUMAN,tr|A0A7P0NMY4|A0A7P0NMY4_HUMAN,tr|Q60FE5|Q60FE5_HUMAN,tr|A0A7I2V3E6|A0A7I2V3E6_HUMAN,tr|A0A087WWY3|A0A087WWY3_HUMAN,tr|F8WE98|F8WE98_HUMAN" 6 1263.693 0.7 139753 6483 3 1263.690938 422.2383 Filamin-A OS=Homo sapiens OX=9606 GN=FLNA PE=1 SV=4 8.75 1653.8 - 923188 - - - -1.6119 - 1.853 0.197 - 209 1 2 1 -0.002 10 0 0 0 1.95E+07 2.78E+07 - - - 2.5371 0.9999 221125_WJC_METTL3_EV_vs_WT_F10.06485.06485.2 0.000307 28-Oct R.NTDQASMPDNTAAQK[136.11].V "sp|P35749|MYH11_HUMAN,sp|P35579|MYH9_HUMAN,tr|A0A494C024|A0A494C024_HUMAN" 3 1598.7086 0.96 139755 6485 2 1598.707923 800.3616 Myosin-11 OS=Homo sapiens OX=9606 GN=MYH11 PE=1 SV=3 4.21 1654.1 - 231091 - - - -0.4228 - 2.253 0.575 - 241.1 1 2 0 -0.0007 15 0 0 0 6.57E+06 6.82E+06 - - - 5.2847 1 221125_WJC_METTL3_EV_vs_WT_F10.06487.06487.2 3.14E-07 18/26 K.K[136.11]GPGEVAGTVTGQK[136.11].R "sp|Q86U44|MTA70_HUMAN,tr|F5H6D8|F5H6D8_HUMAN,tr|H0YFV6|H0YFV6_HUMAN,tr|B4DTN4|B4DTN4_HUMAN" 4 1343.738 0.01 139756 6487 2 1343.736088 672.8763 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 8.59 1654.3 - 5.83E+07 - - - -1.4073 - 3.47 0.565 - 794.1 1 2 0 -0.0019 14 0 0 0 2.33E+07 4.65E+09 - - - 6.3356 0.9731 221125_WJC_METTL3_EV_vs_WT_F10.06489.06489.4 0.0267 Sep-84 R.ALQHSYLHK[136.11]DEGNPE.- "sp|P11802|CDK4_HUMAN,tr|F8VZ13|F8VZ13_HUMAN" 2 1744.826 0.43 139757 6489 4 1744.823265 437.2138 Cyclin-dependent kinase 4 OS=Homo sapiens OX=9606 GN=CDK4 PE=1 SV=2 5.4 1654.5 - 826286 - - - -1.5744 - 1.568 0.224 - 45.6 1 2 1 -0.0027 15 0 0 0 1.12E+07 2.60E+07 - - - 1.3359 0.9987 221125_WJC_METTL3_EV_vs_WT_F10.06491.06491.3 0.000109 Dec-56 R.ALQHSYLHKDEGNPE.- "sp|P11802|CDK4_HUMAN,tr|F8VZ13|F8VZ13_HUMAN" 2 1736.8118 0.49 139759 6491 3 1736.807679 579.9445 Cyclin-dependent kinase 4 OS=Homo sapiens OX=9606 GN=CDK4 PE=1 SV=2 5.4 1654.7 - 715460 - - - -2.3796 - 1.938 0.428 - 112.1 1 2 1 -0.0041 15 0 0 0 2.04E+07 4.12E+07 - - - 5.0371 0.9998 221125_WJC_METTL3_EV_vs_WT_F10.06493.06493.4 4.01E-07 Nov-72 R.KAVVVC[160.03]PKDEDYK.Q "sp|Q00839|HNRPU_HUMAN,tr|A0A1W2PQL0|A0A1W2PQL0_HUMAN,tr|A0A1W2PPL4|A0A1W2PPL4_HUMAN,tr|A0A1W2PQ74|A0A1W2PQ74_HUMAN,tr|Q5RI18|Q5RI18_HUMAN,tr|A0A1W2PP35|A0A1W2PP35_HUMAN,tr|A0A1W2PPS1|A0A1W2PPS1_HUMAN,tr|A0A1W2PRZ7|A0A1W2PRZ7_HUMAN,tr|A0A1W2PPH7|A0A1W2PPH7_HUMAN,tr|A0A1W2PQD4|A0A1W2PQD4_HUMAN,tr|A0A1W2PP34|A0A1W2PP34_HUMAN,tr|A0A1X7SBS1|A0A1X7SBS1_HUMAN" 12 1549.781 0.87 139761 6493 4 1549.77762 388.4525 Heterogeneous nuclear ribonucleoprotein U OS=Homo sapiens OX=9606 GN=HNRNPU PE=1 SV=6 6.11 1655 - 331050 - - - -2.2003 - 2.228 0.515 - 125.9 1 2 1 -0.0034 13 0 0 0 1.05E+08 1.20E+08 - - - 4.0046 0.9716 221125_WJC_METTL3_EV_vs_WT_F10.06505.06505.3 2.55E-05 Dec-76 R.GAEGK[136.11]PGVEAGQEPAEAGER[166.11].L "sp|Q14596|NBR1_HUMAN,tr|B7Z5R6|B7Z5R6_HUMAN" 2 1955.9304 3.58 139767 6505 3 1956.923844 652.9841 Next to BRCA1 gene 1 protein OS=Homo sapiens OX=9606 GN=NBR1 PE=1 SV=3 4.33 1656.6 - 191298 - - - 507.9301 - 2.061 0.509 - 73.1 1 2 0 0.9935 20 0 0 0 9.98E+06 2.79E+06 - - - 5.6941 0.9908 221125_WJC_METTL3_EV_vs_WT_F10.06507.06507.3 0.0226 Aug-40 K.VSNRFSGVPDR.F "sp|A0A075B6R9|KVD24_HUMAN,sp|A0A075B6S2|KVD29_HUMAN,sp|A0A0A0MRZ7|KVD26_HUMAN" 3 1232.6262 31.21 139768 6507 3 1232.62561 411.8827 Probable non-functional immunoglobulin kappa variable 2D-24 OS=Homo sapiens OX=9606 GN=IGKV2D-24 PE=1 SV=1 9.57 1656.8 - 478553 - - - -0.4657 - 1.591 0.266 - 85.4 1 2 1 -0.0006 11 0 0 0 1.45E+07 4.63E+05 - - - 2.8247 1 221125_WJC_METTL3_EV_vs_WT_F10.06509.06509.3 5.41E-09 17/48 R.KAVVVC[160.03]PKDEDYK.Q "sp|Q00839|HNRPU_HUMAN,tr|A0A1W2PQL0|A0A1W2PQL0_HUMAN,tr|A0A1W2PPL4|A0A1W2PPL4_HUMAN,tr|A0A1W2PQ74|A0A1W2PQ74_HUMAN,tr|Q5RI18|Q5RI18_HUMAN,tr|A0A1W2PP35|A0A1W2PP35_HUMAN,tr|A0A1W2PPS1|A0A1W2PPS1_HUMAN,tr|A0A1W2PRZ7|A0A1W2PRZ7_HUMAN,tr|A0A1W2PPH7|A0A1W2PPH7_HUMAN,tr|A0A1W2PQD4|A0A1W2PQD4_HUMAN,tr|A0A1W2PP34|A0A1W2PP34_HUMAN,tr|A0A1X7SBS1|A0A1X7SBS1_HUMAN" 12 1549.781 0.94 139769 6509 3 1549.781288 517.601 Heterogeneous nuclear ribonucleoprotein U OS=Homo sapiens OX=9606 GN=HNRNPU PE=1 SV=6 6.11 1657 - 1.86E+06 - - - 0.1665 - 3.057 0.591 - 322.9 1 2 1 0.0003 13 0 0 0 2.85E+08 3.02E+08 - - - 8.1587 0.9999 221125_WJC_METTL3_EV_vs_WT_F10.06519.06519.4 1.28E-09 13/72 R.K[136.11]AVVVC[160.03]PK[136.11]DEDYK[136.11].Q "sp|Q00839|HNRPU_HUMAN,tr|A0A1W2PQL0|A0A1W2PQL0_HUMAN,tr|A0A1W2PPL4|A0A1W2PPL4_HUMAN,tr|A0A1W2PQ74|A0A1W2PQ74_HUMAN,tr|Q5RI18|Q5RI18_HUMAN,tr|A0A1W2PP35|A0A1W2PP35_HUMAN,tr|A0A1W2PPS1|A0A1W2PPS1_HUMAN,tr|A0A1W2PRZ7|A0A1W2PRZ7_HUMAN,tr|A0A1W2PPH7|A0A1W2PPH7_HUMAN,tr|A0A1W2PQD4|A0A1W2PQD4_HUMAN,tr|A0A1W2PP34|A0A1W2PP34_HUMAN,tr|A0A1X7SBS1|A0A1X7SBS1_HUMAN" 12 1573.8236 0.87 139773 6519 4 1573.82232 394.4632 Heterogeneous nuclear ribonucleoprotein U OS=Homo sapiens OX=9606 GN=HNRNPU PE=1 SV=6 6.11 1658.4 - 1.21E+06 - - - -0.8324 - 2.501 0.542 - 199.9 1 2 1 -0.0013 13 0 0 0 1.05E+08 1.20E+08 - - - 4.2831 1 221125_WJC_METTL3_EV_vs_WT_F10.06521.06521.3 5.61E-06 23/68 K.GTGGASAEGGPTGLAHGR[166.11].L sp|Q96F45|ZN503_HUMAN 1 1561.7473 1.83 139775 6521 3 1561.74819 521.5897 Zinc finger protein 503 OS=Homo sapiens OX=9606 GN=ZNF503 PE=1 SV=1 6.75 1658.6 - 540307 - - - 0.6006 - 3.34 0.5 - 700.7 1 2 0 0.0009 18 0 0 0 5.10E+07 2.79E+07 - - - 7.1172 0.9776 221125_WJC_METTL3_EV_vs_WT_F10.06529.06529.2 4.30E-06 30-Aug F.AGTNTGPNNSNTTFQK[136.11].R "sp|Q9NYF8|BCLF1_HUMAN,tr|H0YF14|H0YF14_HUMAN" 2 1658.774 2.23 139780 6529 2 1658.770377 830.3943 Bcl-2-associated transcription factor 1 OS=Homo sapiens OX=9606 GN=BCLAF1 PE=1 SV=2 8.8 1659.6 - 148387 - - - -2.1703 - 1.648 0.564 - 127.8 1 1 0 -0.0036 16 0 0 0 2.03E+08 9.10E+07 - - - 4.4338 1 221125_WJC_METTL3_EV_vs_WT_F10.06534.06534.2 3.66E-11 16/30 F.AGTNTGPNNSNTTFQK.R "sp|Q9NYF8|BCLF1_HUMAN,tr|H0YF14|H0YF14_HUMAN" 2 1650.7598 2.23 139783 6534 2 1650.758474 826.3872 Bcl-2-associated transcription factor 1 OS=Homo sapiens OX=9606 GN=BCLAF1 PE=1 SV=2 8.8 1660.3 - 614208 - - - -0.7893 - 3.246 0.698 - 995.7 1 1 0 -0.0013 16 0 0 0 2.03E+08 9.10E+07 - - - 7.0908 0.9262 221125_WJC_METTL3_EV_vs_WT_F10.06537.06537.2 0.73 14-Aug V.AGTVTGQK[136.11].R "sp|Q86U44|MTA70_HUMAN,tr|F5H6D8|F5H6D8_HUMAN,tr|H0YFV6|H0YFV6_HUMAN,tr|B4DTN4|B4DTN4_HUMAN" 4 768.4221 0.24 139785 6537 2 768.421331 385.2183 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 8.8 1660.7 - 811374 - - - -1.0242 - 1.805 0.199 - 297 1 1 0 -0.0008 8 0 0 0 1.31E+07 5.57E+07 - - - 2.2917 0.9965 221125_WJC_METTL3_EV_vs_WT_F10.06539.06539.4 0.396 Dec-90 R.QAELEEGRPQHQEQLR.Q "sp|O00461|GOLI4_HUMAN,tr|F8W785|F8W785_HUMAN" 2 1946.9559 1.53 139786 6539 4 1946.955503 487.7462 Golgi integral membrane protein 4 OS=Homo sapiens OX=9606 GN=GOLIM4 PE=1 SV=1 4.91 1661 - 780121 - - - -0.1787 - 2.472 0.23 - 165.7 1 2 0 -0.0003 16 0 0 0 3.13E+07 2.05E+07 - - - 1.5466 0.9997 221125_WJC_METTL3_EV_vs_WT_F10.06542.06542.4 0.000887 15/90 R.QAELEEGR[166.11]PQHQEQLR[166.11].Q "sp|O00461|GOLI4_HUMAN,tr|F8W785|F8W785_HUMAN" 2 1966.9724 1.53 139789 6542 4 1966.970257 492.7504 Golgi integral membrane protein 4 OS=Homo sapiens OX=9606 GN=GOLIM4 PE=1 SV=1 4.91 1661.3 - 827051 - - - -1.0849 - 2.497 0.354 - 242.8 1 2 0 -0.0021 16 0 0 0 3.13E+07 2.05E+07 - - - 2.629 1 221125_WJC_METTL3_EV_vs_WT_F10.06545.06545.3 2.42E-07 17/60 R.QAELEEGRPQHQEQLR.Q "sp|O00461|GOLI4_HUMAN,tr|F8W785|F8W785_HUMAN" 2 1946.9559 1.66 139792 6545 3 1946.96045 649.9926 Golgi integral membrane protein 4 OS=Homo sapiens OX=9606 GN=GOLIM4 PE=1 SV=1 4.91 1661.7 - 264032 - - - 2.3621 - 3.034 0.534 - 369.7 1 2 0 0.0046 16 0 0 0 8.26E+06 4.97E+06 - - - 7.3401 0.9999 221125_WJC_METTL3_EV_vs_WT_F10.06548.06548.3 0.000377 Nov-36 K.HQEELTELHK.K "sp|Q676U5|A16L1_HUMAN,tr|E7EVC7|E7EVC7_HUMAN,tr|C9J8C6|C9J8C6_HUMAN,tr|C9J1B2|C9J1B2_HUMAN" 4 1262.6255 1.85 139793 6548 3 1262.624041 421.8824 Autophagy-related protein 16-1 OS=Homo sapiens OX=9606 GN=ATG16L1 PE=1 SV=2 5.33 1662.1 - 729300 - - - -1.1674 - 1.924 0.42 - 170.9 1 2 0 -0.0015 10 0 0 0 1.52E+07 8.24E+06 - - - 5.1333 0.9999 221125_WJC_METTL3_EV_vs_WT_F10.06550.06550.3 5.57E-05 14/60 R.QAELEEGR[166.11]PQHQEQLR[166.11].Q "sp|O00461|GOLI4_HUMAN,tr|F8W785|F8W785_HUMAN" 2 1966.9724 1.66 139795 6550 3 1966.973308 656.6647 Golgi integral membrane protein 4 OS=Homo sapiens OX=9606 GN=GOLIM4 PE=1 SV=1 4.91 1662.3 - 308432 - - - 0.4662 - 2.262 0.466 - 301.9 1 2 0 0.0009 16 0 0 0 8.26E+06 4.97E+06 - - - 5.8296 0.9984 221125_WJC_METTL3_EV_vs_WT_F10.06558.06558.3 0.00113 Dec-60 K.DPGTVANKKEEEDLAK.A "sp|Q92783|STAM1_HUMAN,tr|A6NMU3|A6NMU3_HUMAN" 2 1742.8687 3.68 139799 6558 3 1742.871683 581.9635 Signal transducing adapter molecule 1 OS=Homo sapiens OX=9606 GN=STAM PE=1 SV=3 4.51 1663.4 - 238932 - - - 1.7351 - 1.939 0.385 - 122 1 2 1 0.003 16 0 0 0 2.21E+07 6.01E+06 - - - 4.5306 0.9999 221125_WJC_METTL3_EV_vs_WT_F10.06562.06562.3 2.04E-05 Nov-68 R.EGK[136.11]PGGTVESGNGEDLTK[136.11].V sp|Q9UK59|DBR1_HUMAN 1 1789.8665 1.1 139801 6562 3 1789.871862 597.6294 Lariat debranching enzyme OS=Homo sapiens OX=9606 GN=DBR1 PE=1 SV=2 4.41 1663.8 - 376340 - - - 3.003 - 2.431 0.568 - 133.6 1 2 0 0.0054 18 0 0 0 6.73E+06 6.11E+06 - - - 7.0831 0.9998 221125_WJC_METTL3_EV_vs_WT_F10.06564.06564.3 6.56E-05 Oct-68 R.EGKPGGTVESGNGEDLTK.V sp|Q9UK59|DBR1_HUMAN 1 1773.8381 1.14 139803 6564 3 1773.836755 592.2866 Lariat debranching enzyme OS=Homo sapiens OX=9606 GN=DBR1 PE=1 SV=2 4.41 1664.1 - 330508 - - - -0.7509 - 1.785 0.42 - 95.9 1 2 0 -0.0013 18 0 0 0 6.99E+06 6.11E+06 - - - 4.665 1 221125_WJC_METTL3_EV_vs_WT_F10.06567.06567.3 6.29E-09 14/56 K.EQNQDSQTEAEELRK.L "sp|Q8N573|OXR1_HUMAN,tr|H0YC07|H0YC07_HUMAN" 2 1803.8235 0.97 139804 6567 3 1803.826744 602.2818 Oxidation resistance protein 1 OS=Homo sapiens OX=9606 GN=OXR1 PE=1 SV=2 4.25 1664.4 - 372254 - - - 1.799 - 2.656 0.608 - 316.4 1 2 0 0.0032 15 0 0 0 1.81E+07 1.86E+07 - - - 7.8666 0.9996 221125_WJC_METTL3_EV_vs_WT_F10.06568.06568.3 6.83E-07 Nov-60 K.DPGTVANK[136.11]K[136.11]EEEDLAK[136.11].A "sp|Q92783|STAM1_HUMAN,tr|A6NMU3|A6NMU3_HUMAN" 2 1766.9113 3.68 139805 6568 3 1766.907387 589.9777 Signal transducing adapter molecule 1 OS=Homo sapiens OX=9606 GN=STAM PE=1 SV=3 4.51 1664.6 - 142812 - - - -2.1914 - 2.048 0.523 - 86.7 1 2 1 -0.0039 16 0 0 0 2.21E+07 6.01E+06 - - - 6.2092 1 221125_WJC_METTL3_EV_vs_WT_F10.06580.06580.3 1.17E-07 17/56 K.EQNQDSQTEAEELR[166.11]K[136.11].L "sp|Q8N573|OXR1_HUMAN,tr|H0YC07|H0YC07_HUMAN" 2 1821.846 0.96 139812 6580 3 1821.844379 608.2893 Oxidation resistance protein 1 OS=Homo sapiens OX=9606 GN=OXR1 PE=1 SV=2 4.25 1666.2 - 629327 - - - -0.8727 - 2.19 0.58 - 282.2 1 2 0 -0.0016 15 0 0 0 1.79E+07 1.86E+07 - - - 7.0515 0.9997 221125_WJC_METTL3_EV_vs_WT_F10.06582.06582.3 0.0068 Dec-48 R.EDSVKPGAHLTVK.K "sp|P51991|ROA3_HUMAN,tr|A0A7I2V5D8|A0A7I2V5D8_HUMAN,tr|A0A7I2V2R3|A0A7I2V2R3_HUMAN,tr|A0A7I2V4J6|A0A7I2V4J6_HUMAN,tr|A0A7I2V4G0|A0A7I2V4G0_HUMAN,tr|A0A7I2V402|A0A7I2V402_HUMAN" 6 1379.7409 1.33 139814 6582 3 1379.739234 460.9209 Heterogeneous nuclear ribonucleoprotein A3 OS=Homo sapiens OX=9606 GN=HNRNPA3 PE=1 SV=2 6.85 1666.5 - 535506 - - - -1.1923 - 2.021 0.358 - 123.8 1 2 0 -0.0016 13 0 0 0 2.40E+08 1.80E+08 - - - 4.4385 0.9997 221125_WJC_METTL3_EV_vs_WT_F10.06585.06585.3 0.000233 15/44 R.HAEKAPTNIVYK.L "sp|P15927|RFA2_HUMAN,tr|Q5TEJ7|Q5TEJ7_HUMAN" 2 1369.7354 1.14 139815 6585 3 1369.734537 457.5857 Replication protein A 32 kDa subunit OS=Homo sapiens OX=9606 GN=RPA2 PE=1 SV=1 8.51 1666.9 - 650890 - - - -0.63 - 2.874 0.387 - 270.9 1 2 1 -0.0009 12 0 0 0 1.99E+07 1.75E+07 - - - 5.7807 1 221125_WJC_METTL3_EV_vs_WT_F10.06586.06586.3 8.01E-07 Dec-64 R.QSTGSAPQGPAYHGVNR[166.11].T "sp|O14497|ARI1A_HUMAN,tr|H0Y488|H0Y488_HUMAN,tr|A0A1B0GTU5|A0A1B0GTU5_HUMAN" 3 1735.8266 1.15 139816 6586 3 1735.82382 579.6161 AT-rich interactive domain-containing protein 1A OS=Homo sapiens OX=9606 GN=ARID1A PE=1 SV=3 8.75 1667 - 263707 - - - -1.5814 - 2.456 0.503 - 159.3 1 2 0 -0.0027 17 0 0 0 6.11E+06 5.33E+06 - - - 6.4172 1 221125_WJC_METTL3_EV_vs_WT_F10.06589.06589.2 1.82E-11 16/24 R.KAVVVC[160.03]PKDEDYK.Q "sp|Q00839|HNRPU_HUMAN,tr|A0A1W2PQL0|A0A1W2PQL0_HUMAN,tr|A0A1W2PPL4|A0A1W2PPL4_HUMAN,tr|A0A1W2PQ74|A0A1W2PQ74_HUMAN,tr|Q5RI18|Q5RI18_HUMAN,tr|A0A1W2PP35|A0A1W2PP35_HUMAN,tr|A0A1W2PPS1|A0A1W2PPS1_HUMAN,tr|A0A1W2PRZ7|A0A1W2PRZ7_HUMAN,tr|A0A1W2PPH7|A0A1W2PPH7_HUMAN,tr|A0A1W2PQD4|A0A1W2PQD4_HUMAN,tr|A0A1W2PP34|A0A1W2PP34_HUMAN,tr|A0A1X7SBS1|A0A1X7SBS1_HUMAN" 12 1549.781 0.85 139819 6589 2 1549.7804 775.8978 Heterogeneous nuclear ribonucleoprotein U OS=Homo sapiens OX=9606 GN=HNRNPU PE=1 SV=6 6.11 1667.3 - 171182 - - - -0.4065 - 3.239 0.724 - 1043.8 1 2 1 -0.0006 13 0 0 0 5.16E+06 6.09E+06 - - - 7.4046 0.9938 221125_WJC_METTL3_EV_vs_WT_F10.06595.06595.4 2.40E-09 15/108 S.LVSGLNSSASEPAK[136.11]EPAK[136.11]K[136.11].S "sp|Q86U44|MTA70_HUMAN,tr|F5H6D8|F5H6D8_HUMAN,tr|H0YFV6|H0YFV6_HUMAN,tr|B4DTN4|B4DTN4_HUMAN" 4 1936.0692 0 139823 6595 4 1936.067437 485.0246 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 8.5 1668.1 - 2.66E+06 - - - -0.8879 - 2.973 0.621 - 148 1 1 1 -0.0017 19 0 0 0 3.63E+05 6.03E+08 - - - 4.9993 0.9998 221125_WJC_METTL3_EV_vs_WT_F10.06597.06597.3 2.21E-06 14/44 R.HAEK[136.11]APTNIVYK[136.11].L "sp|P15927|RFA2_HUMAN,tr|Q5TEJ7|Q5TEJ7_HUMAN" 2 1385.7638 1.14 139825 6597 3 1385.76219 462.9285 Replication protein A 32 kDa subunit OS=Homo sapiens OX=9606 GN=RPA2 PE=1 SV=1 8.51 1668.3 - 831846 - - - -1.1618 - 2.681 0.448 - 212.3 1 2 1 -0.0016 12 0 0 0 1.99E+07 1.75E+07 - - - 6.2679 0.9985 221125_WJC_METTL3_EV_vs_WT_F10.06603.06603.4 0.00181 13/66 K.LK[136.11]QVEDEK[136.11]NSFR[166.11].E sp|P35579|MYH9_HUMAN 1 1517.8048 0.001 139829 6603 4 1517.804715 380.4585 Myosin-9 OS=Homo sapiens OX=9606 GN=MYH9 PE=1 SV=4 6.18 1669 - 733808 - - - -0.0738 - 2.137 0.341 - 143.9 1 2 2 -0.0001 12 0 0 0 0.00E+00 2.14E+07 - - - 2.4814 0.9993 221125_WJC_METTL3_EV_vs_WT_F10.06605.06605.4 0.00153 Oct-90 K.DPGTVANKKEEEDLAK.A "sp|Q92783|STAM1_HUMAN,tr|A6NMU3|A6NMU3_HUMAN" 2 1742.8687 2.53 139830 6605 4 1742.870275 436.7244 Signal transducing adapter molecule 1 OS=Homo sapiens OX=9606 GN=STAM PE=1 SV=3 4.51 1669.3 - 403706 - - - 0.9272 - 2.236 0.39 - 52.6 1 2 1 0.0016 16 0 0 0 1.12E+07 4.42E+06 - - - 2.9036 1 221125_WJC_METTL3_EV_vs_WT_F10.06607.06607.3 1.85E-10 13/60 K.VDC[160.03]TAHSDVC[160.03]SAQGVR[166.11].G sp|Q8NBS9|TXND5_HUMAN 1 1770.7653 0.44 139832 6607 3 1770.767636 591.2624 Thioredoxin domain-containing protein 5 OS=Homo sapiens OX=9606 GN=TXNDC5 PE=1 SV=2 5.21 1669.5 - 395561 - - - 1.3265 - 2.787 0.66 - 214.4 1 2 0 0.0023 16 0 0 0 2.04E+06 4.62E+06 - - - 8.5276 0.9996 221125_WJC_METTL3_EV_vs_WT_F10.06612.06612.3 0.00044 Nov-48 R.EDSVK[136.11]PGAHLTVK[136.11].K "sp|P51991|ROA3_HUMAN,tr|A0A7I2V5D8|A0A7I2V5D8_HUMAN,tr|A0A7I2V2R3|A0A7I2V2R3_HUMAN,tr|A0A7I2V4J6|A0A7I2V4J6_HUMAN,tr|A0A7I2V4G0|A0A7I2V4G0_HUMAN,tr|A0A7I2V402|A0A7I2V402_HUMAN" 6 1395.7693 1.33 139835 6612 3 1395.769693 466.2637 Heterogeneous nuclear ribonucleoprotein A3 OS=Homo sapiens OX=9606 GN=HNRNPA3 PE=1 SV=2 6.85 1670.2 - 8.29E+06 - - - 0.2966 - 1.851 0.341 - 93.8 1 2 0 0.0004 13 0 0 0 2.40E+08 1.80E+08 - - - 4.0111 0.9945 221125_WJC_METTL3_EV_vs_WT_F10.06613.06613.3 1.68E-09 20/72 S.LVSGLNSSASEPAK[136.11]EPAK[136.11]K[136.11].S "sp|Q86U44|MTA70_HUMAN,tr|F5H6D8|F5H6D8_HUMAN,tr|H0YFV6|H0YFV6_HUMAN,tr|B4DTN4|B4DTN4_HUMAN" 4 1936.0692 0.001 139836 6613 3 1936.066512 646.3637 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 8.5 1670.2 - 2.09E+06 - - - -1.3657 - 3.211 0.629 - 293.9 1 1 1 -0.0026 19 0 0 0 0.00E+00 1.75E+08 - - - 8.4181 0.9999 221125_WJC_METTL3_EV_vs_WT_F10.06615.06615.3 9.67E-05 15/36 K.RMHVQLSTSR.L "sp|Q9BWF3|RBM4_HUMAN,sp|Q9BQ04|RBM4B_HUMAN,tr|E9PB51|E9PB51_HUMAN" 3 1213.635 1.18 139838 6615 3 1213.635315 405.5523 RNA-binding protein 4 OS=Homo sapiens OX=9606 GN=RBM4 PE=1 SV=1 12 1670.4 - 1.12E+06 - - - 0.281 - 2.853 0.327 - 521.2 1 2 0 0.0003 10 0 0 0 1.14E+08 9.61E+07 - - - 5.2473 0.9997 221125_WJC_METTL3_EV_vs_WT_F10.06617.06617.2 6.51E-05 24-Sep R.EDSVKPGAHLTVK.K "sp|P51991|ROA3_HUMAN,tr|A0A7I2V5D8|A0A7I2V5D8_HUMAN,tr|A0A7I2V2R3|A0A7I2V2R3_HUMAN,tr|A0A7I2V4J6|A0A7I2V4J6_HUMAN,tr|A0A7I2V4G0|A0A7I2V4G0_HUMAN,tr|A0A7I2V402|A0A7I2V402_HUMAN" 6 1379.7409 1.59 139840 6617 2 1379.739627 690.8777 Heterogeneous nuclear ribonucleoprotein A3 OS=Homo sapiens OX=9606 GN=HNRNPA3 PE=1 SV=2 6.85 1670.7 - 322496 - - - -0.9074 - 1.84 0.432 - 187.7 1 2 0 -0.0013 13 0 0 0 8.81E+06 5.55E+06 - - - 3.7963 1 221125_WJC_METTL3_EV_vs_WT_F10.06621.06621.3 8.33E-09 13/56 K.ESMAGNK[136.11]PANAVLHK[136.11].V "sp|Q14839|CHD4_HUMAN,tr|A0A2R8Y4X2|A0A2R8Y4X2_HUMAN,tr|A0A2U3TZM0|A0A2U3TZM0_HUMAN,tr|A0A2R8YD40|A0A2R8YD40_HUMAN,tr|A0A2R8Y5J0|A0A2R8Y5J0_HUMAN,tr|A0A2R8Y425|A0A2R8Y425_HUMAN,tr|A0A2R8YFK9|A0A2R8YFK9_HUMAN,tr|A0A0C4DGG9|A0A0C4DGG9_HUMAN,tr|A0A2R8YFD8|A0A2R8YFD8_HUMAN,tr|A0A2R8YDW2|A0A2R8YDW2_HUMAN,tr|A0A2R8Y7I0|A0A2R8Y7I0_HUMAN,tr|F5GWX5|F5GWX5_HUMAN,tr|A0A2R8Y795|A0A2R8Y795_HUMAN,tr|A0A2R8Y7M9|A0A2R8Y7M9_HUMAN,tr|A0A2R8Y521|A0A2R8Y521_HUMAN,tr|A0A2R8YDJ9|A0A2R8YDJ9_HUMAN,tr|A0A2R8Y212|A0A2R8Y212_HUMAN" 17 1581.8268 1.6 139842 6621 3 1581.828273 528.2829 Chromodomain-helicase-DNA-binding protein 4 OS=Homo sapiens OX=9606 GN=CHD4 PE=1 SV=2 8.69 1671.2 - 441760 - - - 0.9242 - 2.637 0.497 - 160.9 1 2 0 0.0015 15 0 0 0 3.28E+07 2.06E+07 - - - 6.6108 0.9998 221125_WJC_METTL3_EV_vs_WT_F10.06622.06622.3 1.71E-06 Dec-44 K.FQQEK[136.11]EELINK[136.11]K[136.11].N "sp|Q92878|RAD50_HUMAN,tr|A0A1W2PQ90|A0A1W2PQ90_HUMAN" 2 1556.8625 0.97 139843 6622 3 1556.865105 519.9614 DNA repair protein RAD50 OS=Homo sapiens OX=9606 GN=RAD50 PE=1 SV=1 6.23 1671.4 - 600090 - - - 1.7002 - 1.887 0.554 - 104.5 1 2 1 0.0026 12 0 0 0 1.52E+07 1.56E+07 - - - 6.4759 0.9972 221125_WJC_METTL3_EV_vs_WT_F10.06623.06623.3 0.0132 Nov-56 K.ESMAGNKPANAVLHK.V "sp|Q14839|CHD4_HUMAN,tr|A0A2R8Y4X2|A0A2R8Y4X2_HUMAN,tr|A0A2U3TZM0|A0A2U3TZM0_HUMAN,tr|A0A2R8YD40|A0A2R8YD40_HUMAN,tr|A0A2R8Y5J0|A0A2R8Y5J0_HUMAN,tr|A0A2R8Y425|A0A2R8Y425_HUMAN,tr|A0A2R8YFK9|A0A2R8YFK9_HUMAN,tr|A0A0C4DGG9|A0A0C4DGG9_HUMAN,tr|A0A2R8YFD8|A0A2R8YFD8_HUMAN,tr|A0A2R8YDW2|A0A2R8YDW2_HUMAN,tr|A0A2R8Y7I0|A0A2R8Y7I0_HUMAN,tr|F5GWX5|F5GWX5_HUMAN,tr|A0A2R8Y795|A0A2R8Y795_HUMAN,tr|A0A2R8Y7M9|A0A2R8Y7M9_HUMAN,tr|A0A2R8Y521|A0A2R8Y521_HUMAN,tr|A0A2R8YDJ9|A0A2R8YDJ9_HUMAN,tr|A0A2R8Y212|A0A2R8Y212_HUMAN" 17 1565.7984 1.57 139844 6623 3 1565.802253 522.9401 Chromodomain-helicase-DNA-binding protein 4 OS=Homo sapiens OX=9606 GN=CHD4 PE=1 SV=2 8.69 1671.5 - 504014 - - - 2.4537 - 1.683 0.301 - 109.2 1 2 0 0.0038 15 0 0 0 2.35E+07 1.50E+07 - - - 3.2532 0.9999 221125_WJC_METTL3_EV_vs_WT_F10.06624.06624.3 0.000177 Dec-52 K.HIHITQATETTTTR.H sp|Q14677|EPN4_HUMAN 1 1608.822 1.6 139845 6624 3 1608.823384 537.2813 Clathrin interactor 1 OS=Homo sapiens OX=9606 GN=CLINT1 PE=1 SV=1 6.92 1671.6 - 442772 - - - 0.8708 - 2.013 0.419 - 234.5 1 2 0 0.0014 14 0 0 0 9.95E+06 6.20E+06 - - - 5.0703 0.9976 221125_WJC_METTL3_EV_vs_WT_F10.06625.06625.3 8.13E-06 14/44 E.DSVKPGAHLTVK.K "sp|P51991|ROA3_HUMAN,tr|A0A7I2V5D8|A0A7I2V5D8_HUMAN,tr|A0A7I2V2R3|A0A7I2V2R3_HUMAN,tr|A0A7I2V4J6|A0A7I2V4J6_HUMAN,tr|A0A7I2V4G0|A0A7I2V4G0_HUMAN,tr|A0A7I2V402|A0A7I2V402_HUMAN" 6 1250.6983 1.41 139846 6625 3 1250.698878 417.9067 Heterogeneous nuclear ribonucleoprotein A3 OS=Homo sapiens OX=9606 GN=HNRNPA3 PE=1 SV=2 8.6 1671.8 - 431148 - - - 0.4733 - 2.505 0.521 - 183.3 1 1 0 0.0006 12 0 0 0 1.01E+07 7.16E+06 - - - 6.8938 0.9975 221125_WJC_METTL3_EV_vs_WT_F10.06628.06628.2 0.0178 24-Aug R.EDSVK[136.11]PGAHLTVK[136.11].K "sp|P51991|ROA3_HUMAN,tr|A0A7I2V5D8|A0A7I2V5D8_HUMAN,tr|A0A7I2V2R3|A0A7I2V2R3_HUMAN,tr|A0A7I2V4J6|A0A7I2V4J6_HUMAN,tr|A0A7I2V4G0|A0A7I2V4G0_HUMAN,tr|A0A7I2V402|A0A7I2V402_HUMAN" 6 1395.7693 1.59 139847 6628 2 1395.77036 698.8919 Heterogeneous nuclear ribonucleoprotein A3 OS=Homo sapiens OX=9606 GN=HNRNPA3 PE=1 SV=2 6.85 1672.2 - 277825 - - - 0.7745 - 1.39 0.254 - 136.4 1 2 0 0.0011 13 0 0 0 8.81E+06 5.55E+06 - - - 1.7619 0.9999 221125_WJC_METTL3_EV_vs_WT_F10.06630.06630.3 2.27E-05 18/44 K.LK[136.11]QVEDEK[136.11]NSFR[166.11].E sp|P35579|MYH9_HUMAN 1 1517.8048 0.52 139849 6630 3 1517.806241 506.9422 Myosin-9 OS=Homo sapiens OX=9606 GN=MYH9 PE=1 SV=4 6.18 1672.4 - 1.70E+06 - - - 0.9316 - 3.068 0.527 - 365.7 1 2 2 0.0014 12 0 0 0 2.40E+07 4.64E+07 - - - 7.5225 1 221125_WJC_METTL3_EV_vs_WT_F10.06635.06635.3 3.45E-07 17/52 K.K[136.11]GPGEVAGTVTGQK[136.11].R "sp|Q86U44|MTA70_HUMAN,tr|F5H6D8|F5H6D8_HUMAN,tr|H0YFV6|H0YFV6_HUMAN,tr|B4DTN4|B4DTN4_HUMAN" 4 1343.738 0.02 139853 6635 3 1343.73975 448.9199 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 8.59 1673 - 7.90E+06 - - - 1.318 - 3.243 0.577 - 527.1 1 2 0 0.0018 14 0 0 0 2.13E+08 1.28E+10 - - - 8.0991 0.9999 221125_WJC_METTL3_EV_vs_WT_F10.06640.06640.2 0.000554 22-Nov K.KGDEC[160.03]ELLGHSK.N sp|P49411|EFTU_HUMAN 1 1371.6453 1.76 139857 6640 2 1371.647038 686.8299 "Elongation factor Tu, mitochondrial OS=Homo sapiens OX=9606 GN=TUFM PE=1 SV=2" 5.45 1673.6 - 203293 - - - 1.2933 - 2.412 0.533 - 385.4 1 2 0 0.0018 12 0 0 0 1.04E+07 5.93E+06 - - - 5.2938 1 221125_WJC_METTL3_EV_vs_WT_F10.06641.06641.3 5.03E-07 13/72 K.AVVTHSSGNHGQALTYAAK[136.11].L "sp|Q9GZT4|SRR_HUMAN,tr|I3L3N0|I3L3N0_HUMAN,tr|I3L4B4|I3L4B4_HUMAN" 3 1918.9741 0.99 139858 6641 3 1918.976446 640.6653 Serine racemase OS=Homo sapiens OX=9606 GN=SRR PE=1 SV=1 8.65 1673.7 - 194609 - - - 1.2361 - 2.475 0.557 - 145.6 1 2 0 0.0024 19 0 0 0 2.35E+06 2.38E+06 - - - 6.9758 0.9739 221125_WJC_METTL3_EV_vs_WT_F10.06642.06642.2 0.323 May-32 R.SSPSGPSNPSNPSVEEK[136.11].L "sp|Q8WY22|BRI3B_HUMAN,tr|A0A5F9ZHY7|A0A5F9ZHY7_HUMAN" 2 1706.7839 1.24 139859 6642 2 1706.782316 854.3992 BRI3-binding protein OS=Homo sapiens OX=9606 GN=BRI3BP PE=1 SV=1 4.53 1673.8 - 77368.4 - - - -0.9122 - 1.062 0.12 - 57.6 1 2 0 -0.0016 17 0 0 0 1.28E+07 1.03E+07 - - - 0.0747 0.9972 221125_WJC_METTL3_EV_vs_WT_F10.06645.06645.3 0.025 13/36 R.ERRPTWAEER.R "sp|Q8ND56|LS14A_HUMAN,tr|A0A096LP11|A0A096LP11_HUMAN,tr|A0A140TA76|A0A140TA76_HUMAN,tr|A0A0G2JQ95|A0A0G2JQ95_HUMAN" 4 1328.6585 0.91 139860 6645 3 1328.660341 443.8935 Protein LSM14 homolog A OS=Homo sapiens OX=9606 GN=LSM14A PE=1 SV=3 6.33 1674.2 - 786943 - - - 1.351 - 2.22 0.271 - 246.1 1 2 1 0.0018 10 0 0 0 2.81E+08 3.10E+08 - - - 3.89 0.9989 221125_WJC_METTL3_EV_vs_WT_F10.06647.06647.3 0.0082 13/36 R.ER[166.11]R[166.11]PTWAEER[166.11].R "sp|Q8ND56|LS14A_HUMAN,tr|A0A096LP11|A0A096LP11_HUMAN,tr|A0A140TA76|A0A140TA76_HUMAN,tr|A0A0G2JQ95|A0A0G2JQ95_HUMAN" 4 1358.6834 0.91 139862 6647 3 1358.684945 453.9017 Protein LSM14 homolog A OS=Homo sapiens OX=9606 GN=LSM14A PE=1 SV=3 6.33 1674.5 - 1.25E+06 - - - 1.1695 - 2.102 0.343 - 242.2 1 2 1 0.0016 10 0 0 0 2.81E+08 3.10E+08 - - - 4.5332 0.9909 221125_WJC_METTL3_EV_vs_WT_F10.06648.06648.3 4.67E-08 Dec-64 V.SGLNSSASEPAK[136.11]EPAK[136.11]K[136.11].S "sp|Q86U44|MTA70_HUMAN,tr|F5H6D8|F5H6D8_HUMAN,tr|H0YFV6|H0YFV6_HUMAN,tr|B4DTN4|B4DTN4_HUMAN" 4 1723.9167 0 139863 6648 3 1723.91668 575.6462 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 8.22 1674.6 - 210470 - - - 0.0012 - 2.463 0.567 - 147.6 1 1 1 0 17 0 0 0 2.80E+04 1.00E+07 - - - 7.1386 0.9388 221125_WJC_METTL3_EV_vs_WT_F10.06653.06653.3 0.0127 Sep-60 F.AGTNTGPNNSNTTFQK.R "sp|Q9NYF8|BCLF1_HUMAN,tr|H0YF14|H0YF14_HUMAN" 2 1650.7598 2.38 139866 6653 3 1650.757873 551.2605 Bcl-2-associated transcription factor 1 OS=Homo sapiens OX=9606 GN=BCLAF1 PE=1 SV=2 8.8 1675.3 - 337275 - - - -1.1534 - 1.614 0.354 - 94.9 1 1 0 -0.0019 16 0 0 0 5.21E+07 2.19E+07 - - - 3.7145 0.9993 221125_WJC_METTL3_EV_vs_WT_F10.06654.06654.3 0.000917 Jul-72 K.AVVTHSSGNHGQALTYAAK.L "sp|Q9GZT4|SRR_HUMAN,tr|I3L3N0|I3L3N0_HUMAN,tr|I3L4B4|I3L4B4_HUMAN" 3 1910.9599 0.99 139867 6654 3 1910.958954 637.9939 Serine racemase OS=Homo sapiens OX=9606 GN=SRR PE=1 SV=1 8.65 1675.4 - 183312 - - - -0.4814 - 1.47 0.37 - 36 1 2 0 -0.0009 19 0 0 0 2.35E+06 2.38E+06 - - - 3.6114 0.9996 221125_WJC_METTL3_EV_vs_WT_F10.06668.06668.2 0.00746 16-Jun R.SQESGYYDR.M "sp|P43243|MATR3_HUMAN,tr|A8MXP9|A8MXP9_HUMAN,tr|D6R991|D6R991_HUMAN,tr|A0A0R4J2E8|A0A0R4J2E8_HUMAN,tr|D6REM6|D6REM6_HUMAN" 5 1103.452 1.17 139875 6668 2 1103.450695 552.7333 Matrin-3 OS=Homo sapiens OX=9606 GN=MATR3 PE=1 SV=2 4.37 1677.4 - 114480 - - - -1.1527 - 1.434 0.486 - 179.2 1 2 0 -0.0013 9 0 0 0 3.00E+06 2.56E+06 - - - 3.673 1 221125_WJC_METTL3_EV_vs_WT_F10.06675.06675.3 2.64E-07 17/52 K.HPSAEQSSHIDVVR[166.11].F sp|Q69YN4|VIR_HUMAN 1 1570.7727 0.97 139876 6675 3 1570.774173 524.5982 Protein virilizer homolog OS=Homo sapiens OX=9606 GN=VIRMA PE=1 SV=2 5.99 1678.5 - 671768 - - - 0.9136 - 3.105 0.546 - 250 1 2 0 0.0014 14 0 0 0 1.34E+07 1.38E+07 - - - 7.638 0.9943 221125_WJC_METTL3_EV_vs_WT_F10.06679.06679.3 0.000581 Sep-52 R.TSKEPPSSPLQPQK.E "sp|Q92615|LAR4B_HUMAN,tr|A0A087X183|A0A087X183_HUMAN,tr|H0Y4V9|H0Y4V9_HUMAN" 3 1522.7991 1.33 139879 6679 3 1522.80305 508.607 La-related protein 4B OS=Homo sapiens OX=9606 GN=LARP4B PE=1 SV=3 8.26 1679 - 328804 - - - 2.5795 - 1.725 0.354 - 76.3 1 2 1 0.0039 14 0 0 0 3.77E+08 2.84E+08 - - - 3.9346 0.9932 221125_WJC_METTL3_EV_vs_WT_F10.06680.06680.2 0.000127 30-Aug K.TQASSSFQDSSQPAGK[136.11].A sp|P46087|NOP2_HUMAN 1 1632.7471 1.02 139880 6680 2 1632.752899 817.3808 Probable 28S rRNA (cytosine(4447)-C(5))-methyltransferase OS=Homo sapiens OX=9606 GN=NOP2 PE=1 SV=2 5.5 1679.1 - 103998 - - - 3.556 - 1.682 0.279 - 168.1 1 2 0 0.0058 16 0 0 0 1.26E+07 1.23E+07 - - - 2.3783 1 221125_WJC_METTL3_EV_vs_WT_F10.06685.06685.3 6.27E-09 15/44 K.K[136.11]GDEC[160.03]ELLGHSK[136.11].N sp|P49411|EFTU_HUMAN 1 1387.6737 1.54 139882 6685 3 1387.675251 463.5652 "Elongation factor Tu, mitochondrial OS=Homo sapiens OX=9606 GN=TUFM PE=1 SV=2" 5.45 1679.8 - 6.43E+06 - - - 1.1436 - 2.771 0.594 - 477 1 2 0 0.0016 12 0 0 0 4.15E+08 2.69E+08 - - - 7.9872 1 221125_WJC_METTL3_EV_vs_WT_F10.06692.06692.3 1.67E-06 14/36 R.K[136.11]QDSGHLDLR[166.11].N "sp|Q86U44|MTA70_HUMAN,tr|B4E349|B4E349_HUMAN,tr|F5H6D8|F5H6D8_HUMAN,tr|B4DTN4|B4DTN4_HUMAN" 4 1185.6221 0.07 139887 6692 3 1185.623561 396.2146 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 6.75 1680.8 - 1.27E+06 - - - 1.228 - 2.328 0.543 - 249.1 1 2 0 0.0015 10 0 0 0 4.27E+06 6.47E+07 - - - 7.0613 1 221125_WJC_METTL3_EV_vs_WT_F10.06693.06693.2 4.07E-08 30-Dec K.TQASSSFQDSSQPAGK.A sp|P46087|NOP2_HUMAN 1 1624.7329 1.02 139888 6693 2 1624.734186 813.3737 Probable 28S rRNA (cytosine(4447)-C(5))-methyltransferase OS=Homo sapiens OX=9606 GN=NOP2 PE=1 SV=2 5.5 1680.9 - 186380 - - - 0.7958 - 2.639 0.675 - 341.3 1 2 0 0.0013 16 0 0 0 1.26E+07 1.23E+07 - - - 6.4119 0.9999 221125_WJC_METTL3_EV_vs_WT_F10.06694.06694.3 0.222 24/52 K.RLEEEEAAAEKEDR.G sp|Q5T280|CI114_HUMAN 1 1673.7857 0.81 139889 6694 3 1673.788172 558.9358 Putative methyltransferase C9orf114 OS=Homo sapiens OX=9606 GN=SPOUT1 PE=1 SV=3 4.31 1681 - 681924 - - - 1.5026 - 4.312 0.537 - 1382.5 1 2 1 0.0025 14 0 0 0 1.16E+07 1.43E+07 - - - 8.41 0.9999 221125_WJC_METTL3_EV_vs_WT_F10.06695.06695.2 3.40E-07 28-Sep R.TSSTSSSVNSQTLNR[166.11].N "sp|Q9NYJ8|TAB2_HUMAN,tr|A0A1B0GV57|A0A1B0GV57_HUMAN" 2 1577.7521 1.83 139890 6695 2 1577.754098 789.8833 TGF-beta-activated kinase 1 and MAP3K7-binding protein 2 OS=Homo sapiens OX=9606 GN=TAB2 PE=1 SV=1 9.41 1681.2 - 129393 - - - 1.2904 - 2.29 0.612 - 254.2 1 2 0 0.002 15 0 0 0 8.33E+06 4.55E+06 - - - 5.5976 0.9917 221125_WJC_METTL3_EV_vs_WT_F10.06698.06698.3 3.56E-07 Dec-72 S.LVSGLNSSASEPAK[136.11]EPAKK[136.11].S "sp|Q86U44|MTA70_HUMAN,tr|F5H6D8|F5H6D8_HUMAN,tr|H0YFV6|H0YFV6_HUMAN,tr|B4DTN4|B4DTN4_HUMAN" 4 1928.055 - 139891 6698 3 1928.053333 643.6923 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 8.5 1681.6 - 195280 - - - -0.8418 - 2.522 0.58 - 87.2 1 1 1 -0.0016 19 0 0 0 - - - - - 7.2786 0.9994 221125_WJC_METTL3_EV_vs_WT_F10.06709.06709.3 0.0283 14/32 R.RKDDSYFDR.Y "sp|Q9HCD5|NCOA5_HUMAN,tr|Q5JY17|Q5JY17_HUMAN" 2 1200.5523 1.71 139899 6709 3 1200.553712 401.1914 Nuclear receptor coactivator 5 OS=Homo sapiens OX=9606 GN=NCOA5 PE=1 SV=2 6.04 1682.9 - 423361 - - - 1.1345 - 2.396 0.359 - 524 1 2 1 0.0014 9 0 0 0 1.88E+08 1.10E+08 - - - 5.1756 1 221125_WJC_METTL3_EV_vs_WT_F10.06710.06710.3 2.17E-07 Nov-56 R.KTGQAPGYSYTAANK.N "sp|P99999|CYC_HUMAN,tr|C9JFR7|C9JFR7_HUMAN" 2 1555.7631 0.98 139900 6710 3 1555.766451 519.595 Cytochrome c OS=Homo sapiens OX=9606 GN=CYCS PE=1 SV=2 9.53 1683.1 - 417910 - - - 2.1726 - 2.339 0.577 - 120.9 1 2 0 0.0034 15 0 0 0 1.26E+07 1.28E+07 - - - 7.1893 0.9994 221125_WJC_METTL3_EV_vs_WT_F10.06715.06715.4 0.000509 14/72 K.VMEEEGLKDEEKR.L sp|Q15208|STK38_HUMAN 1 1590.7559 3.3 139903 6715 4 1590.759742 398.6963 Serine\threonine-protein kinase 38 OS=Homo sapiens OX=9606 GN=STK38 PE=1 SV=1 4.42 1683.7 - 1.31E+06 - - - 2.3919 - 2.552 0.443 - 141.8 1 2 1 0.0038 13 0 0 0 3.18E+07 9.63E+06 - - - 3.4282 0.9671 221125_WJC_METTL3_EV_vs_WT_F10.06716.06716.3 0.0511 Jul-60 K.TQASSSFQDSSQPAGK.A sp|P46087|NOP2_HUMAN 1 1624.7329 1.78 139904 6716 3 1624.738408 542.5849 Probable 28S rRNA (cytosine(4447)-C(5))-methyltransferase OS=Homo sapiens OX=9606 GN=NOP2 PE=1 SV=2 5.5 1683.9 - 212255 - - - 3.3944 - 1.184 0.277 - 42.8 1 2 0 0.0055 16 0 0 0 6.52E+06 3.66E+06 - - - 2.0601 1 221125_WJC_METTL3_EV_vs_WT_F10.06719.06719.3 2.72E-08 13/52 K.IHSDC[160.03]AANQQVTYR.L sp|Q02413|DSG1_HUMAN 1 1661.758 1.29 139905 6719 3 1661.76165 554.9266 Desmoglein-1 OS=Homo sapiens OX=9606 GN=DSG1 PE=1 SV=2 6.73 1684.3 - 277220 - - - 2.1947 - 2.442 0.594 - 263.4 1 2 0 0.0036 14 0 0 0 9.50E+06 7.37E+06 - - - 7.5342 0.999 221125_WJC_METTL3_EV_vs_WT_F10.06724.06724.2 0.000271 26-Sep K.K[136.11]GPGEVAGTVTGQK[136.11].R "sp|Q86U44|MTA70_HUMAN,tr|F5H6D8|F5H6D8_HUMAN,tr|H0YFV6|H0YFV6_HUMAN,tr|B4DTN4|B4DTN4_HUMAN" 4 1343.738 0.01 139909 6724 2 1343.742827 672.8763 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 8.59 1684.9 - 155483 - - - 3.6078 - 1.944 0.521 - 168.9 1 2 0 0.0048 14 0 0 0 2.33E+07 4.65E+09 - - - 4.5557 0.9998 221125_WJC_METTL3_EV_vs_WT_F10.06728.06728.3 4.35E-06 14/64 R.LNSEQSQALQHQQETGR.S "sp|Q92817|EVPL_HUMAN,tr|K7EKI0|K7EKI0_HUMAN" 2 1952.93 999 139911 6728 3 1952.936368 651.984 Envoplakin OS=Homo sapiens OX=9606 GN=EVPL PE=1 SV=3 5.4 1685.5 - 194959 - - - 3.2454 - 2.82 0.448 - 248 1 2 0 0.0063 17 0 0 0 3.77E+06 0.00E+00 - - - 6.1521 0.9998 221125_WJC_METTL3_EV_vs_WT_F10.06731.06731.3 7.70E-06 16/52 K.RKGDEVDGVDEVAK.K "sp|P09874|PARP1_HUMAN,tr|A0A7I2V5E9|A0A7I2V5E9_HUMAN,tr|A0A7I2V625|A0A7I2V625_HUMAN,tr|A0A7I2V3E1|A0A7I2V3E1_HUMAN" 4 1515.7529 1.27 139913 6731 3 1515.756938 506.2582 Poly [ADP-ribose] polymerase 1 OS=Homo sapiens OX=9606 GN=PARP1 PE=1 SV=4 4.44 1685.9 - 611593 - - - 2.664 - 3.074 0.523 - 352 1 2 1 0.004 14 0 0 0 4.09E+07 3.23E+07 - - - 7.3542 0.9994 221125_WJC_METTL3_EV_vs_WT_F10.06732.06732.3 3.41E-05 Dec-48 K.K[136.11]SPDSDVAATLK[136.11]K[136.11].Q "sp|O60841|IF2P_HUMAN,tr|A0A087WUT6|A0A087WUT6_HUMAN" 2 1382.7831 0.55 139914 6732 3 1382.785265 461.935 Eukaryotic translation initiation factor 5B OS=Homo sapiens OX=9606 GN=EIF5B PE=1 SV=4 8.5 1686 - 771577 - - - 1.5331 - 2.293 0.286 - 185.6 1 2 0 0.0021 13 0 0 0 1.09E+07 1.98E+07 - - - 3.978 0.9999 221125_WJC_METTL3_EV_vs_WT_F10.06736.06736.3 1.23E-05 15/44 R.HDNIKPSDEVYR.R sp|Q86UA1|PRP39_HUMAN 1 1471.7056 0.27 139916 6736 3 1471.709553 491.5758 Pre-mRNA-processing factor 39 OS=Homo sapiens OX=9606 GN=PRPF39 PE=1 SV=3 5.38 1686.5 - 346029 - - - 2.7159 - 2.522 0.531 - 292.9 1 2 0 0.004 12 0 0 0 6.76E+06 2.53E+07 - - - 7.0231 1 221125_WJC_METTL3_EV_vs_WT_F10.06740.06740.3 6.08E-10 15/56 R.RPSQDDVEAAPEETR.A sp|O94761|RECQ4_HUMAN 1 1698.7809 1.59 139920 6740 3 1698.782226 567.2676 ATP-dependent DNA helicase Q4 OS=Homo sapiens OX=9606 GN=RECQL4 PE=1 SV=2 4.18 1687 - 174897 - - - 0.777 - 3.367 0.64 - 332.3 1 2 0 0.0013 15 0 0 0 6.60E+06 4.14E+06 - - - 8.8428 0.9999 221125_WJC_METTL3_EV_vs_WT_F10.06745.06745.3 1.05E-06 16/52 K.R[166.11]K[136.11]GDEVDGVDEVAK[136.11].K "sp|P09874|PARP1_HUMAN,tr|A0A7I2V5E9|A0A7I2V5E9_HUMAN,tr|A0A7I2V625|A0A7I2V625_HUMAN,tr|A0A7I2V3E1|A0A7I2V3E1_HUMAN" 4 1541.7896 1.26 139922 6745 3 1541.791554 514.9371 Poly [ADP-ribose] polymerase 1 OS=Homo sapiens OX=9606 GN=PARP1 PE=1 SV=4 4.44 1687.7 - 1.45E+06 - - - 1.2868 - 2.703 0.548 - 337.8 1 2 1 0.002 14 0 0 0 4.06E+07 3.23E+07 - - - 7.2917 0.9836 221125_WJC_METTL3_EV_vs_WT_F10.06747.06747.4 0.066 Aug-78 K.R[166.11]K[136.11]GDEVDGVDEVAK[136.11].K "sp|P09874|PARP1_HUMAN,tr|A0A7I2V5E9|A0A7I2V5E9_HUMAN,tr|A0A7I2V625|A0A7I2V625_HUMAN,tr|A0A7I2V3E1|A0A7I2V3E1_HUMAN" 4 1541.7896 0.03 139924 6747 4 1541.793208 386.4547 Poly [ADP-ribose] polymerase 1 OS=Homo sapiens OX=9606 GN=PARP1 PE=1 SV=4 4.44 1688 - 199066 - - - 2.3596 - 1.581 0.271 - 33.5 1 2 1 0.0036 14 0 0 0 1.18E+05 4.47E+06 - - - 1.7505 1 221125_WJC_METTL3_EV_vs_WT_F10.06748.06748.3 2.26E-05 Nov-56 R.R[166.11]PSQDDVEAAPEETR[166.11].A sp|O94761|RECQ4_HUMAN 1 1718.7974 1.59 139925 6748 3 1718.796427 573.9398 ATP-dependent DNA helicase Q4 OS=Homo sapiens OX=9606 GN=RECQL4 PE=1 SV=2 4.18 1688.1 - 139406 - - - -0.5929 - 2.481 0.519 - 171.1 1 2 0 -0.001 15 0 0 0 6.64E+06 4.18E+06 - - - 6.6971 0.9831 221125_WJC_METTL3_EV_vs_WT_F10.06753.06753.3 0.00752 14/36 R.R[166.11]R[166.11]EEEGIQLR[166.11].K "sp|O60684|IMA7_HUMAN,sp|O15131|IMA6_HUMAN,sp|P52294|IMA5_HUMAN,tr|C9JWD9|C9JWD9_HUMAN,tr|S4R3E5|S4R3E5_HUMAN,tr|C9JYI4|C9JYI4_HUMAN,tr|C9J352|C9J352_HUMAN,tr|C9J4U1|C9J4U1_HUMAN,tr|F2Z3G4|F2Z3G4_HUMAN,tr|Q5TD90|Q5TD90_HUMAN" 10 1314.7147 0.93 139928 6753 3 1314.717865 439.2455 Importin subunit alpha-7 OS=Homo sapiens OX=9606 GN=KPNA6 PE=1 SV=1 6.23 1688.8 - 507002 - - - 2.4401 - 1.773 0.255 - 252.3 1 2 1 0.0032 10 0 0 0 3.84E+07 4.12E+07 - - - 3.0546 0.9997 221125_WJC_METTL3_EV_vs_WT_F10.06760.06760.3 3.81E-05 13/32 R.R[166.11]K[136.11]DDSYFDR[166.11].Y "sp|Q9HCD5|NCOA5_HUMAN,tr|Q5JY17|Q5JY17_HUMAN" 2 1228.5831 1.71 139933 6760 3 1228.584852 410.535 Nuclear receptor coactivator 5 OS=Homo sapiens OX=9606 GN=NCOA5 PE=1 SV=2 6.04 1689.6 - 5.08E+06 - - - 1.4342 - 2.218 0.461 - 390.9 1 2 1 0.0018 9 0 0 0 1.89E+08 1.10E+08 - - - 6.08 0.9949 221125_WJC_METTL3_EV_vs_WT_F10.06766.06766.2 1.08E-06 16-Dec R.RKDDSYFDR.Y "sp|Q9HCD5|NCOA5_HUMAN,tr|Q5JY17|Q5JY17_HUMAN" 2 1200.5523 5.06 139937 6766 2 1200.555902 601.2835 Nuclear receptor coactivator 5 OS=Homo sapiens OX=9606 GN=NCOA5 PE=1 SV=2 6.04 1690.5 - 402143 - - - 2.9586 - 2.449 0.482 - 423.7 1 2 1 0.0036 9 0 0 0 1.56E+07 3.09E+06 - - - 5.1912 0.9999 221125_WJC_METTL3_EV_vs_WT_F10.06767.06767.3 1.66E-06 19/60 K.GVEAVAIHGGKDQEER.T sp|Q9UJV9|DDX41_HUMAN 1 1693.8384 0.98 139938 6767 3 1693.841729 565.6201 Probable ATP-dependent RNA helicase DDX41 OS=Homo sapiens OX=9606 GN=DDX41 PE=1 SV=2 4.83 1690.7 - 400362 - - - 1.9884 - 3.557 0.569 - 412.6 1 2 1 0.0034 16 0 0 0 4.21E+07 4.29E+07 - - - 8.1387 0.9998 221125_WJC_METTL3_EV_vs_WT_F10.06768.06768.4 1.21E-06 17/90 K.GVEAVAIHGGK[136.11]DQEER[166.11].T sp|Q9UJV9|DDX41_HUMAN 1 1711.8608 0.97 139939 6768 4 1711.86381 428.9725 Probable ATP-dependent RNA helicase DDX41 OS=Homo sapiens OX=9606 GN=DDX41 PE=1 SV=2 4.83 1690.8 - 643569 - - - 1.7402 - 2.835 0.474 - 156.2 1 2 1 0.003 16 0 0 0 4.34E+07 4.49E+07 - - - 3.7179 1 221125_WJC_METTL3_EV_vs_WT_F10.06775.06775.3 2.46E-06 22/60 K.GVEAVAIHGGK[136.11]DQEER[166.11].T sp|Q9UJV9|DDX41_HUMAN 1 1711.8608 0.98 139944 6775 3 1711.863994 571.6276 Probable ATP-dependent RNA helicase DDX41 OS=Homo sapiens OX=9606 GN=DDX41 PE=1 SV=2 4.83 1691.6 - 957533 - - - 1.8477 - 3.656 0.595 - 565.2 1 2 1 0.0032 16 0 0 0 4.20E+07 4.29E+07 - - - 8.4991 0.9996 221125_WJC_METTL3_EV_vs_WT_F10.06782.06782.4 7.48E-05 Dec-72 K.TVTEYK[136.11]IDEDGK[136.11]K[136.11].F "sp|O75821|EIF3G_HUMAN,tr|K7ER90|K7ER90_HUMAN,tr|K7EL20|K7EL20_HUMAN,tr|K7ENA8|K7ENA8_HUMAN,tr|K7EL60|K7EL60_HUMAN" 5 1548.8098 0.93 139949 6782 4 1548.81305 388.2097 Eukaryotic translation initiation factor 3 subunit G OS=Homo sapiens OX=9606 GN=EIF3G PE=1 SV=2 4.78 1692.5 - 401625 - - - 2.1281 - 2.296 0.465 - 85.6 1 2 1 0.0033 13 0 0 0 3.61E+07 3.88E+07 - - - 3.5806 0.9836 221125_WJC_METTL3_EV_vs_WT_F10.06783.06783.3 0.000259 13/48 K.K[136.11]EAPPMEK[136.11]PEVVK[136.11].T "sp|P62841|RS15_HUMAN,tr|K7EJ78|K7EJ78_HUMAN,tr|K7EM56|K7EM56_HUMAN,tr|A0A0B4J2B4|A0A0B4J2B4_HUMAN,tr|S4R456|S4R456_HUMAN,tr|K7ELC2|K7ELC2_HUMAN,tr|K7EQJ5|K7EQJ5_HUMAN,tr|S4R417|S4R417_HUMAN" 8 1504.8386 1.59 139950 6783 3 1504.845 502.6201 40S ribosomal protein S15 OS=Homo sapiens OX=9606 GN=RPS15 PE=1 SV=2 6.23 1692.7 - 299350 - - - 4.2855 - 1.999 0.227 - 203.3 1 2 0 0.0064 13 0 0 0 1.75E+07 1.10E+07 - - - 2.947 0.9995 221125_WJC_METTL3_EV_vs_WT_F10.06786.06786.3 7.10E-07 15/48 K.TVTEYK[136.11]IDEDGK[136.11]K[136.11].F "sp|O75821|EIF3G_HUMAN,tr|K7ER90|K7ER90_HUMAN,tr|K7EL20|K7EL20_HUMAN,tr|K7ENA8|K7ENA8_HUMAN,tr|K7EL60|K7EL60_HUMAN" 5 1548.8098 0.51 139951 6786 3 1548.81347 517.2772 Eukaryotic translation initiation factor 3 subunit G OS=Homo sapiens OX=9606 GN=EIF3G PE=1 SV=2 4.78 1693.1 - 608736 - - - 2.3993 - 2.491 0.464 - 215.5 1 2 1 0.0037 13 0 0 0 1.64E+07 3.23E+07 - - - 6.1867 0.9997 221125_WJC_METTL3_EV_vs_WT_F10.06787.06787.4 0.000108 13/72 K.TVTEYKIDEDGKK.F "sp|O75821|EIF3G_HUMAN,tr|K7ER90|K7ER90_HUMAN,tr|K7EL20|K7EL20_HUMAN,tr|K7ENA8|K7ENA8_HUMAN,tr|K7EL60|K7EL60_HUMAN" 5 1524.7672 0.93 139952 6787 4 1524.77014 382.1991 Eukaryotic translation initiation factor 3 subunit G OS=Homo sapiens OX=9606 GN=EIF3G PE=1 SV=2 4.78 1693.2 - 579654 - - - 1.9583 - 2.199 0.485 - 100.5 1 2 1 0.003 13 0 0 0 3.60E+07 3.88E+07 - - - 3.7388 0.9999 221125_WJC_METTL3_EV_vs_WT_F10.06791.06791.3 0.000125 Sep-40 K.ENGFTQHVYHK[136.11].Y sp|Q6PKG0|LARP1_HUMAN 1 1366.6509 0.95 139954 6791 3 1366.654558 456.5576 La-related protein 1 OS=Homo sapiens OX=9606 GN=LARP1 PE=1 SV=2 7.01 1693.8 - 793567 - - - 2.6415 - 1.98 0.53 - 75.5 1 2 0 0.0036 11 0 0 0 5.27E+07 5.56E+07 - - - 6.3885 0.9998 221125_WJC_METTL3_EV_vs_WT_F10.06793.06793.4 1.62E-07 20/90 K.GVEAVAIHGGKDQEER.T sp|Q9UJV9|DDX41_HUMAN 1 1693.8384 0.97 139956 6793 4 1693.843258 424.4669 Probable ATP-dependent RNA helicase DDX41 OS=Homo sapiens OX=9606 GN=DDX41 PE=1 SV=2 4.83 1694 - 1.84E+06 - - - 2.8911 - 3.153 0.578 - 286.8 1 2 1 0.0049 16 0 0 0 4.35E+07 4.49E+07 - - - 4.6601 0.988 221125_WJC_METTL3_EV_vs_WT_F10.06794.06794.3 0.0432 Jun-44 R.TSHGEVISVPHK[136.11].L sp|Q13505|MTX1_HUMAN 1 1297.687 1.08 139957 6794 3 1297.689856 433.5696 Metaxin-1 OS=Homo sapiens OX=9606 GN=MTX1 PE=1 SV=3 6.61 1694.1 - 302966 - - - 2.2008 - 1.376 0.247 - 51.1 1 2 0 0.0029 12 0 0 0 4.33E+07 4.02E+07 - - - 2.1777 0.9976 221125_WJC_METTL3_EV_vs_WT_F10.06803.06803.3 0.0108 Oct-60 R.SRADAGHAGVSANMMK.K sp|Q9Y657|SPIN1_HUMAN 1 1601.7402 0.9 139962 6803 3 1601.739387 534.9207 Spindlin-1 OS=Homo sapiens OX=9606 GN=SPIN1 PE=1 SV=3 8.49 1695.3 - 194090 - - - -0.535 - 1.538 0.373 - 83.7 1 2 1 -0.0009 16 0 0 0 5.99E+06 6.64E+06 - - - 3.8029 0.9887 221125_WJC_METTL3_EV_vs_WT_F10.06811.06811.3 0.0135 13/40 R.SAKEEIAEYRR.Q "sp|P07197|NFM_HUMAN,tr|E7ESP9|E7ESP9_HUMAN,tr|E7EMV2|E7EMV2_HUMAN" 3 1350.6892 2.63 139967 6811 3 1350.692906 451.237 Neurofilament medium polypeptide OS=Homo sapiens OX=9606 GN=NEFM PE=1 SV=3 5.95 1696.4 - 525806 - - - 2.7601 - 1.974 0.272 - 226.5 1 2 1 0.0037 11 0 0 0 3.41E+07 1.30E+07 - - - 3.5034 0.9998 221125_WJC_METTL3_EV_vs_WT_F10.06812.06812.3 0.00013 13/44 R.TSHGEVISVPHK.L sp|Q13505|MTX1_HUMAN 1 1289.6728 1.08 139968 6812 3 1289.675554 430.8982 Metaxin-1 OS=Homo sapiens OX=9606 GN=MTX1 PE=1 SV=3 6.61 1696.5 - 411509 - - - 2.1354 - 2.022 0.439 - 211.2 1 2 0 0.0028 12 0 0 0 4.32E+07 4.01E+07 - - - 5.3853 0.9999 221125_WJC_METTL3_EV_vs_WT_F10.06823.06823.3 3.14E-06 15/56 R.SYSC[160.03]QVTHEGSTVEK.T "sp|B9A064|IGLL5_HUMAN,sp|P0CG04|IGLC1_HUMAN,sp|P0DOY2|IGLC2_HUMAN,sp|P0DOY3|IGLC3_HUMAN,sp|P0CF74|IGLC6_HUMAN,tr|A0A5H1ZRQ4|A0A5H1ZRQ4_HUMAN,tr|A0A0B4J231|A0A0B4J231_HUMAN" 7 1710.7519 2520.29 139971 6823 3 1710.755866 571.2579 Immunoglobulin lambda-like polypeptide 5 OS=Homo sapiens OX=9606 GN=IGLL5 PE=2 SV=2 5.38 1698.3 - 988502 - - - 2.3101 - 2.35 0.548 - 150.4 1 2 0 0.004 15 0 0 0 1.46E+08 5.80E+04 - - - 6.878 0.9972 221125_WJC_METTL3_EV_vs_WT_F10.06825.06825.4 0.0532 Sep-96 K.VQADIHDTQAAAADEHR.T sp|Q8N5C8|TAB3_HUMAN 1 1846.8558 1.61 139973 6825 4 1846.859026 462.7212 TGF-beta-activated kinase 1 and MAP3K7-binding protein 3 OS=Homo sapiens OX=9606 GN=TAB3 PE=1 SV=3 4.64 1698.5 - 263008 - - - 1.7457 - 1.547 0.273 - 34.3 1 2 0 0.0032 17 0 0 0 5.43E+06 3.38E+06 - - - 1.7528 1 221125_WJC_METTL3_EV_vs_WT_F10.06829.06829.3 1.58E-05 13/40 R.KFSENPHVYQR.H sp|O75319|DUS11_HUMAN 1 1403.6946 1.23 139975 6829 3 1403.696947 468.9055 RNA\RNP complex-1-interacting phosphatase OS=Homo sapiens OX=9606 GN=DUSP11 PE=1 SV=2 8.6 1699.1 - 640428 - - - 1.6734 - 2.58 0.511 - 307.7 1 2 0 0.0023 11 0 0 0 3.37E+07 2.73E+07 - - - 6.929 0.9689 221125_WJC_METTL3_EV_vs_WT_F10.06831.06831.3 0.000165 Nov-44 N.KIDRPEAISEER.L "sp|Q9Y6B6|SAR1B_HUMAN,tr|D6RD69|D6RD69_HUMAN,tr|D6R9R5|D6R9R5_HUMAN,tr|Q9H029|Q9H029_HUMAN" 4 1441.7525 1.1 139977 6831 3 1441.756111 481.5914 GTP-binding protein SAR1b OS=Homo sapiens OX=9606 GN=SAR1B PE=1 SV=1 4.87 1699.4 - 353563 - - - 2.5004 - 1.954 0.42 - 211 1 1 0 0.0036 12 0 0 0 2.30E+07 2.10E+07 - - - 5.0784 0.9238 221125_WJC_METTL3_EV_vs_WT_F10.06836.06836.3 0.0924 Sep-52 R.DKQPGETNDLSAPK.K "tr|Q5JRY3|Q5JRY3_HUMAN,tr|Q5JRY5|Q5JRY5_HUMAN,tr|C6ZRK5|C6ZRK5_HUMAN,tr|H0YEE5|H0YEE5_HUMAN" 4 1498.7264 0.46 139980 6836 3 1498.730413 500.5827 Transcription factor 7-like 2 (Fragment) OS=Homo sapiens OX=9606 GN=TCF7L2 PE=1 SV=2 4.56 1700.1 - 129120 - - - 2.7103 - 1.548 0.22 - 96.8 1 2 1 0.0041 14 0 0 0 7.42E+06 1.60E+07 - - - 2.1529 0.9994 221125_WJC_METTL3_EV_vs_WT_F10.06837.06837.2 0.0069 28-Jun R.SYSC[160.03]QVTHEGSTVEK.T "sp|B9A064|IGLL5_HUMAN,sp|P0CG04|IGLC1_HUMAN,sp|P0DOY2|IGLC2_HUMAN,sp|P0DOY3|IGLC3_HUMAN,sp|P0CF74|IGLC6_HUMAN,tr|A0A5H1ZRQ4|A0A5H1ZRQ4_HUMAN,tr|A0A0B4J231|A0A0B4J231_HUMAN" 7 1710.7519 999 139981 6837 2 1710.755764 856.3832 Immunoglobulin lambda-like polypeptide 5 OS=Homo sapiens OX=9606 GN=IGLL5 PE=2 SV=2 5.38 1700.2 - 77218 - - - 2.2505 - 1.382 0.55 - 82.1 1 2 0 0.0038 15 0 0 0 5.03E+06 0.00E+00 - - - 3.8975 0.9458 221125_WJC_METTL3_EV_vs_WT_F10.06840.06840.3 0.000251 Nov-44 N.K[136.11]IDR[166.11]PEAISEER[166.11].L "sp|Q9Y6B6|SAR1B_HUMAN,tr|D6RD69|D6RD69_HUMAN,tr|D6R9R5|D6R9R5_HUMAN,tr|Q9H029|Q9H029_HUMAN" 4 1469.7832 1.14 139982 6840 3 1469.788809 490.935 GTP-binding protein SAR1b OS=Homo sapiens OX=9606 GN=SAR1B PE=1 SV=1 4.87 1700.7 - 483164 - - - 3.7849 - 2.05 0.438 - 217.9 1 1 0 0.0056 12 0 0 0 2.52E+07 2.21E+07 - - - 5.4115 0.9998 221125_WJC_METTL3_EV_vs_WT_F10.06845.06845.3 8.08E-06 15/52 K.YVAEIEK[136.11]EK[136.11]EENEK[136.11].K "sp|O14818|PSA7_HUMAN,tr|H0Y586|H0Y586_HUMAN" 2 1760.8895 0.56 139985 6845 3 1760.892968 587.9704 Proteasome subunit alpha type-7 OS=Homo sapiens OX=9606 GN=PSMA7 PE=1 SV=1 4.48 1701.3 - 442310 - - - 1.9922 - 2.733 0.533 - 204.9 1 2 2 0.0035 14 0 0 0 3.14E+07 5.56E+07 - - - 7.1533 0.9998 221125_WJC_METTL3_EV_vs_WT_F10.06850.06850.3 1.38E-05 15/52 R.HDSVFVAAHTSAGK[136.11].T sp|Q15477|SKIV2_HUMAN 1 1433.7143 1.23 139987 6850 3 1433.71993 478.912 Helicase SKI2W OS=Homo sapiens OX=9606 GN=SKIV2L PE=1 SV=3 6.92 1702.1 - 383233 - - - 3.9429 - 2.348 0.545 - 233.6 1 2 0 0.0057 14 0 0 0 1.55E+07 1.26E+07 - - - 6.883 0.9376 221125_WJC_METTL3_EV_vs_WT_F10.06853.06853.4 0.0581 Nov-90 R.AIQGGTSHHLGQNFSK[136.11].M sp|P07814|SYEP_HUMAN 1 1688.8474 0.84 139988 6853 4 1688.854201 423.2191 Bifunctional glutamate\proline--tRNA ligase OS=Homo sapiens OX=9606 GN=EPRS1 PE=1 SV=5 8.81 1702.5 - 469159 - - - 4.0175 - 1.571 0.205 - 48.5 1 2 0 0.0068 16 0 0 0 6.38E+07 7.55E+07 - - - 1.1676 0.9999 221125_WJC_METTL3_EV_vs_WT_F10.06855.06855.3 0.000429 14/64 K.SWAQASVTHGAHGDGGR.A sp|P48634|PRC2A_HUMAN 1 1692.7717 0.89 139989 6855 3 1692.775471 565.2645 Protein PRRC2A OS=Homo sapiens OX=9606 GN=PRRC2A PE=1 SV=3 6.66 1702.8 - 384354 - - - 2.2401 - 2.418 0.469 - 193.4 1 2 0 0.0038 17 0 0 0 9.40E+06 1.06E+07 - - - 5.9984 0.9998 221125_WJC_METTL3_EV_vs_WT_F10.06859.06859.3 0.000256 13/60 R.AIQGGTSHHLGQNFSK[136.11].M sp|P07814|SYEP_HUMAN 1 1688.8474 0.85 139991 6859 3 1688.851193 563.9564 Bifunctional glutamate\proline--tRNA ligase OS=Homo sapiens OX=9606 GN=EPRS1 PE=1 SV=5 8.81 1703.3 - 575023 - - - 2.2364 - 2.177 0.454 - 148.6 1 2 0 0.0038 16 0 0 0 5.73E+07 6.78E+07 - - - 5.5967 0.9996 221125_WJC_METTL3_EV_vs_WT_F10.06861.06861.3 0.00106 13/52 K.YVAEIEKEKEENEK.K "sp|O14818|PSA7_HUMAN,tr|H0Y586|H0Y586_HUMAN" 2 1736.8469 0.56 139993 6861 3 1736.849384 579.9562 Proteasome subunit alpha type-7 OS=Homo sapiens OX=9606 GN=PSMA7 PE=1 SV=1 4.48 1703.6 - 629689 - - - 1.4532 - 2.306 0.436 - 149.5 1 2 2 0.0025 14 0 0 0 3.14E+07 5.56E+07 - - - 5.6207 0.9998 221125_WJC_METTL3_EV_vs_WT_F10.06870.06870.3 2.01E-05 13/60 R.AIQGGTSHHLGQNFSK.M sp|P07814|SYEP_HUMAN 1 1680.8332 0.85 139998 6870 3 1680.837802 561.285 Bifunctional glutamate\proline--tRNA ligase OS=Homo sapiens OX=9606 GN=EPRS1 PE=1 SV=5 8.81 1704.7 - 726078 - - - 2.7284 - 2.153 0.468 - 132.5 1 2 0 0.0046 16 0 0 0 5.73E+07 6.78E+07 - - - 5.7241 0.9298 221125_WJC_METTL3_EV_vs_WT_F10.06872.06872.4 0.00142 Dec-78 K.YVAEIEKEKEENEK.K "sp|O14818|PSA7_HUMAN,tr|H0Y586|H0Y586_HUMAN" 2 1736.8469 0.56 140000 6872 4 1736.851865 435.219 Proteasome subunit alpha type-7 OS=Homo sapiens OX=9606 GN=PSMA7 PE=1 SV=1 4.48 1704.9 - 811085 - - - 2.8817 - 2.179 0.208 - 66.1 1 2 2 0.005 14 0 0 0 3.00E+07 5.34E+07 - - - 1.3185 0.9997 221125_WJC_METTL3_EV_vs_WT_F10.06875.06875.3 8.34E-07 13/48 R.QFQMNDQDGKENR.L sp|Q5JSZ5|PRC2B_HUMAN 1 1608.6951 1.46 140001 6875 3 1608.700216 537.239 Protein PRRC2B OS=Homo sapiens OX=9606 GN=PRRC2B PE=1 SV=2 4.56 1705.5 - 571474 - - - 3.2001 - 2.566 0.585 - 262.5 1 2 1 0.0051 13 0 0 0 4.19E+07 2.88E+07 - - - 7.6157 1 221125_WJC_METTL3_EV_vs_WT_F10.06880.06880.4 1.89E-09 15/90 R.AIQGGTSHHLGQNFSK.M sp|P07814|SYEP_HUMAN 1 1680.8332 0.85 140003 6880 4 1680.837049 421.2156 Bifunctional glutamate\proline--tRNA ligase OS=Homo sapiens OX=9606 GN=EPRS1 PE=1 SV=5 8.81 1706.1 - 1.28E+06 - - - 2.2804 - 2.856 0.554 - 124.1 1 2 0 0.0038 16 0 0 0 6.36E+07 7.46E+07 - - - 4.4166 1 221125_WJC_METTL3_EV_vs_WT_F10.06883.06883.3 5.08E-06 Nov-52 R.NHIILQENAQHATR[166.11].F "sp|Q69YN2|C19L1_HUMAN,tr|A0A286YF56|A0A286YF56_HUMAN" 2 1653.8575 0.51 140006 6883 3 1653.859301 552.2931 CWF19-like protein 1 OS=Homo sapiens OX=9606 GN=CWF19L1 PE=1 SV=2 6.92 1706.5 - 121822 - - - 1.1065 - 2.349 0.486 - 205.3 1 2 0 0.0018 14 0 0 0 6.98E+06 1.36E+07 - - - 6.2274 0.8931 221125_WJC_METTL3_EV_vs_WT_F10.06888.06888.3 0.000128 Aug-36 N.YHK[136.11]FDSEYER[166.11].M "sp|P43243|MATR3_HUMAN,tr|A8MXP9|A8MXP9_HUMAN,tr|D6R991|D6R991_HUMAN,tr|A0A0R4J2E8|A0A0R4J2E8_HUMAN,tr|H0Y8T4|H0Y8T4_HUMAN,tr|D6REM6|D6REM6_HUMAN" 6 1390.6273 1.3 140008 6888 3 1390.630988 464.5497 Matrin-3 OS=Homo sapiens OX=9606 GN=MATR3 PE=1 SV=2 5.45 1707.2 - 304425 - - - 2.688 - 1.523 0.506 - 85.8 1 1 1 0.0037 10 0 0 0 1.61E+07 1.24E+07 - - - 5.4089 1 221125_WJC_METTL3_EV_vs_WT_F10.06889.06889.2 3.70E-06 22-Nov K.VGGTSDVEVNEK.K "sp|P10809|CH60_HUMAN,tr|A0A7I2V2X6|A0A7I2V2X6_HUMAN,tr|A0A7I2YQK6|A0A7I2YQK6_HUMAN,tr|A0A7I2V599|A0A7I2V599_HUMAN" 4 1232.5885 1.39 140009 6889 2 1232.588707 617.3015 "60 kDa heat shock protein, mitochondrial OS=Homo sapiens OX=9606 GN=HSPD1 PE=1 SV=2" 4.14 1707.3 - 138240 - - - 0.1996 - 2.467 0.589 - 504.7 1 2 0 0.0002 12 0 0 0 1.89E+07 1.36E+07 - - - 5.7672 0.9998 221125_WJC_METTL3_EV_vs_WT_F10.06902.06902.3 1.98E-07 17/52 R.TSKEPPSSPLQPQK.E "sp|Q92615|LAR4B_HUMAN,tr|A0A087X183|A0A087X183_HUMAN,tr|H0Y4V9|H0Y4V9_HUMAN" 3 1522.7991 1.33 140015 6902 3 1522.803995 508.607 La-related protein 4B OS=Homo sapiens OX=9606 GN=LARP4B PE=1 SV=3 8.26 1709.1 - 3.64E+06 - - - 3.2 - 2.975 0.581 - 308.5 1 2 1 0.0049 14 0 0 0 3.77E+08 2.83E+08 - - - 7.9136 0.9997 221125_WJC_METTL3_EV_vs_WT_F10.06903.06903.3 2.32E-05 16/52 R.TSK[136.11]EPPSSPLQPQK[136.11].E "sp|Q92615|LAR4B_HUMAN,tr|A0A087X183|A0A087X183_HUMAN,tr|H0Y4V9|H0Y4V9_HUMAN" 3 1538.8275 1.33 140016 6903 3 1538.832137 513.9498 La-related protein 4B OS=Homo sapiens OX=9606 GN=LARP4B PE=1 SV=3 8.26 1709.2 - 2.89E+06 - - - 2.999 - 2.884 0.52 - 326.9 1 2 1 0.0046 14 0 0 0 3.76E+08 2.83E+08 - - - 7.151 0.9992 221125_WJC_METTL3_EV_vs_WT_F10.06909.06909.3 0.000559 Aug-56 K.QNAQC[160.03]LHGDIAQSQR.E sp|Q9BQ39|DDX50_HUMAN 1 1724.8013 1.46 140018 6909 3 1724.803194 575.941 ATP-dependent RNA helicase DDX50 OS=Homo sapiens OX=9606 GN=DDX50 PE=1 SV=1 6.74 1710 - 116602 - - - 1.1184 - 1.585 0.349 - 80.7 1 2 0 0.0019 15 0 0 0 1.07E+07 7.33E+06 - - - 3.6323 0.9869 221125_WJC_METTL3_EV_vs_WT_F10.06916.06916.3 0.0201 Sep-48 K.VEQATK[136.11]PSFESGR[166.11].R "sp|P38159|RBMX_HUMAN,tr|H3BT71|H3BT71_HUMAN,tr|H0Y6E7|H0Y6E7_HUMAN" 3 1452.7328 1.86 140023 6916 3 1452.736036 485.2515 "RNA-binding motif protein, X chromosome OS=Homo sapiens OX=9606 GN=RBMX PE=1 SV=3" 6.11 1711 - 181969 - - - 2.2434 - 1.349 0.25 - 82.5 1 2 0 0.0033 13 0 0 0 2.32E+07 1.25E+07 - - - 2.138 0.9994 221125_WJC_METTL3_EV_vs_WT_F10.06918.06918.3 0.000716 Nov-36 R.K[136.11]QDSGHLDLR[166.11].N "sp|Q86U44|MTA70_HUMAN,tr|B4E349|B4E349_HUMAN,tr|F5H6D8|F5H6D8_HUMAN,tr|B4DTN4|B4DTN4_HUMAN" 4 1185.6221 0.07 140024 6918 3 1185.625138 396.2146 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 6.75 1711.2 - 1.84E+06 - - - 2.5582 - 1.878 0.371 - 163.4 1 2 0 0.003 10 0 0 0 1.05E+07 1.49E+08 - - - 4.5159 0.9999 221125_WJC_METTL3_EV_vs_WT_F10.06921.06921.2 0.000897 22-Oct K.VGGTSDVEVNEK[136.11].K "sp|P10809|CH60_HUMAN,tr|A0A7I2V2X6|A0A7I2V2X6_HUMAN,tr|A0A7I2YQK6|A0A7I2YQK6_HUMAN,tr|A0A7I2V599|A0A7I2V599_HUMAN" 4 1240.6027 1.39 140025 6921 2 1240.603703 621.3086 "60 kDa heat shock protein, mitochondrial OS=Homo sapiens OX=9606 GN=HSPD1 PE=1 SV=2" 4.14 1711.6 - 450012 - - - 0.8399 - 2.544 0.525 - 505.7 1 2 0 0.001 12 0 0 0 1.89E+07 1.36E+07 - - - 5.3751 0.9271 221125_WJC_METTL3_EV_vs_WT_F10.06935.06935.3 3.52E-06 Oct-36 N.YHKFDSEYER.M "sp|P43243|MATR3_HUMAN,tr|A8MXP9|A8MXP9_HUMAN,tr|D6R991|D6R991_HUMAN,tr|A0A0R4J2E8|A0A0R4J2E8_HUMAN,tr|H0Y8T4|H0Y8T4_HUMAN,tr|D6REM6|D6REM6_HUMAN" 6 1372.6048 0.92 140031 6935 3 1372.6097 458.5422 Matrin-3 OS=Homo sapiens OX=9606 GN=MATR3 PE=1 SV=2 5.45 1713.7 - 340294 - - - 3.5844 - 2.051 0.536 - 139.1 1 1 1 0.0049 10 0 0 0 1.65E+07 1.78E+07 - - - 6.6123 0.9999 221125_WJC_METTL3_EV_vs_WT_F10.06941.06941.3 1.64E-06 17/64 K.AGYSTDESSSSSLHATR[166.11].T sp|P51116|FXR2_HUMAN 1 1764.779 1.45 140034 6941 3 1764.785692 589.2669 Fragile X mental retardation syndrome-related protein 2 OS=Homo sapiens OX=9606 GN=FXR2 PE=1 SV=2 5.32 1714.5 - 252913 - - - 3.7891 - 2.357 0.644 - 156.6 1 2 0 0.0067 17 0 0 0 1.50E+08 1.03E+08 - - - 7.8841 0.9647 221125_WJC_METTL3_EV_vs_WT_F10.06943.06943.3 0.0324 Jul-48 K.KAEGEPQEESPLK.S "sp|Q9NYF8|BCLF1_HUMAN,tr|E9PKI6|E9PKI6_HUMAN,tr|A0A1W2PQ43|A0A1W2PQ43_HUMAN,tr|E9PK91|E9PK91_HUMAN,tr|E9PJA7|E9PJA7_HUMAN,tr|E9PK09|E9PK09_HUMAN,tr|E9PQN2|E9PQN2_HUMAN" 7 1440.7096 2.59 140036 6943 3 1440.716226 481.2438 Bcl-2-associated transcription factor 1 OS=Homo sapiens OX=9606 GN=BCLAF1 PE=1 SV=2 4.49 1714.8 - 253117 - - - 4.5721 - 1.497 0.263 - 41.9 1 2 0 0.0066 13 0 0 0 1.61E+07 6.21E+06 - - - 2.5643 0.9999 221125_WJC_METTL3_EV_vs_WT_F10.06948.06948.3 0.0011 Oct-36 K.HTNYTMEHIR.V "sp|O43707|ACTN4_HUMAN,sp|P35609|ACTN2_HUMAN,sp|P12814|ACTN1_HUMAN,tr|A0A804HK61|A0A804HK61_HUMAN,tr|H7C5W8|H7C5W8_HUMAN,tr|A0A804HJU8|A0A804HJU8_HUMAN,tr|A0A804HIN7|A0A804HIN7_HUMAN,tr|H0YJ11|H0YJ11_HUMAN,tr|A0A494C060|A0A494C060_HUMAN,tr|H9KV75|H9KV75_HUMAN,tr|A0A804HLF4|A0A804HLF4_HUMAN,tr|H0YJW3|H0YJW3_HUMAN,tr|A0A7I2V4Y4|A0A7I2V4Y4_HUMAN,tr|A0A804HII9|A0A804HII9_HUMAN,tr|A0A804HL31|A0A804HL31_HUMAN,tr|A0A494C1A0|A0A494C1A0_HUMAN,tr|F5GXS2|F5GXS2_HUMAN,tr|A0A804HI95|A0A804HI95_HUMAN,tr|A0A804HKE2|A0A804HKE2_HUMAN,tr|A0A804HLD0|A0A804HLD0_HUMAN,tr|H7C144|H7C144_HUMAN" 21 1300.5983 1.33 140039 6948 3 1300.601408 434.54 Alpha-actinin-4 OS=Homo sapiens OX=9606 GN=ACTN4 PE=1 SV=2 6.92 1715.6 - 399462 - - - 2.425 - 2.236 0.478 - 156.3 1 2 0 0.0032 10 0 0 0 1.01E+07 7.60E+06 - - - 6.2184 0.9363 221125_WJC_METTL3_EV_vs_WT_F10.06949.06949.3 0.00291 13/44 R.SK[136.11]R[166.11]PALFSSSAK[136.11].A "sp|Q9Y5Q8|TF3C5_HUMAN,tr|Q5T7U1|Q5T7U1_HUMAN,tr|H7BY84|H7BY84_HUMAN" 3 1303.7459 0.57 140040 6949 3 1303.750749 435.5892 General transcription factor 3C polypeptide 5 OS=Homo sapiens OX=9606 GN=GTF3C5 PE=1 SV=2 11.17 1715.7 - 437745 - - - 3.7538 - 2.155 0.188 - 196.7 1 2 1 0.0049 12 0 0 0 7.64E+06 1.35E+07 - - - 2.7629 0.9998 221125_WJC_METTL3_EV_vs_WT_F10.06950.06950.3 2.23E-08 20/52 R.RLAQDGAHVVVSSR.K "sp|Q9BTZ2|DHRS4_HUMAN,tr|F5GWZ1|F5GWZ1_HUMAN" 2 1493.8063 1.43 140041 6950 3 1493.813028 498.9427 Dehydrogenase\reductase SDR family member 4 OS=Homo sapiens OX=9606 GN=DHRS4 PE=1 SV=3 9.61 1715.8 - 361373 - - - 4.522 - 2.793 0.568 - 467.4 1 2 0 0.0068 14 0 0 0 7.43E+07 5.20E+07 - - - 7.6004 0.9999 221125_WJC_METTL3_EV_vs_WT_F10.06951.06951.3 1.66E-06 19/52 R.R[166.11]LAQDGAHVVVSSR[166.11].K "sp|Q9BTZ2|DHRS4_HUMAN,tr|F5GWZ1|F5GWZ1_HUMAN" 2 1513.8228 1.43 140042 6951 3 1513.826822 505.6149 Dehydrogenase\reductase SDR family member 4 OS=Homo sapiens OX=9606 GN=DHRS4 PE=1 SV=3 9.61 1716 - 352641 - - - 2.6483 - 2.595 0.461 - 421.1 1 2 0 0.004 14 0 0 0 7.43E+07 5.20E+07 - - - 6.2128 1 221125_WJC_METTL3_EV_vs_WT_F10.06955.06955.3 1.71E-10 22/64 K.AGYSTDESSSSSLHATR.T sp|P51116|FXR2_HUMAN 1 1754.7707 1.45 140044 6955 3 1754.774265 585.9309 Fragile X mental retardation syndrome-related protein 2 OS=Homo sapiens OX=9606 GN=FXR2 PE=1 SV=2 5.32 1716.5 - 1.64E+06 - - - 2.0117 - 3.942 0.663 - 461.7 1 2 0 0.0035 17 0 0 0 1.50E+08 1.04E+08 - - - 9.3961 0.9999 221125_WJC_METTL3_EV_vs_WT_F10.06957.06957.3 7.04E-07 Oct-64 K.SNASTLESHETEEPAAK.K sp|Q9UJA5|TRM6_HUMAN 1 1799.8174 0.29 140046 6957 3 1799.82138 600.9464 tRNA (adenine(58)-N(1))-methyltransferase non-catalytic subunit TRM6 OS=Homo sapiens OX=9606 GN=TRMT6 PE=1 SV=1 4.48 1716.8 - 154765 - - - 2.2386 - 2.282 0.481 - 89.8 1 2 0 0.004 17 0 0 0 4.90E+06 1.67E+07 - - - 5.9859 1 221125_WJC_METTL3_EV_vs_WT_F10.06969.06969.3 2.97E-07 15/56 K.DQEPK[136.11]PSPEPAAVSR[166.11].G sp|Q9H7S9|ZN703_HUMAN 1 1624.8176 1.85 140052 6969 3 1624.820259 542.6131 Zinc finger protein 703 OS=Homo sapiens OX=9606 GN=ZNF703 PE=1 SV=1 4.68 1718.4 - 440625 - - - 1.655 - 2.559 0.534 - 245.4 1 2 0 0.0027 15 0 0 0 8.67E+08 4.68E+08 - - - 6.9446 1 221125_WJC_METTL3_EV_vs_WT_F10.06982.06982.3 3.04E-08 15/56 K.DQEPKPSPEPAAVSR.G sp|Q9H7S9|ZN703_HUMAN 1 1606.7951 1.85 140060 6982 3 1606.796752 536.6056 Zinc finger protein 703 OS=Homo sapiens OX=9606 GN=ZNF703 PE=1 SV=1 4.68 1720.1 - 1.73E+06 - - - 1.0281 - 2.748 0.584 - 253.4 1 2 0 0.0017 15 0 0 0 8.68E+08 4.69E+08 - - - 7.6883 0.9981 221125_WJC_METTL3_EV_vs_WT_F10.06984.06984.4 0.00176 Sep-78 K.IYPSRDEYEAHQER.V "sp|Q99496|RING2_HUMAN,tr|X6RFN3|X6RFN3_HUMAN" 2 1791.8176 1.68 140062 6984 4 1791.821529 448.9617 E3 ubiquitin-protein ligase RING2 OS=Homo sapiens OX=9606 GN=RNF2 PE=1 SV=1 4.83 1720.3 - 592216 - - - 2.1782 - 1.85 0.369 - 47.1 1 2 1 0.0039 14 0 0 0 4.68E+07 2.79E+07 - - - 2.6606 0.9783 221125_WJC_METTL3_EV_vs_WT_F10.06986.06986.3 0.00421 Nov-36 E.LATDPELEK[136.11]K[136.11].L "sp|Q86U44|MTA70_HUMAN,tr|B4E349|B4E349_HUMAN,tr|F5H6D8|F5H6D8_HUMAN,tr|H0YFV6|H0YFV6_HUMAN,tr|B4DTN4|B4DTN4_HUMAN" 5 1158.6467 0.01 140064 6986 3 1158.645402 387.2228 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 4.68 1720.5 - 362087 - - - -1.1237 - 2.136 0.342 - 146.8 1 1 0 -0.0013 10 0 0 0 3.70E+05 6.04E+07 - - - 4.569 0.9998 221125_WJC_METTL3_EV_vs_WT_F10.06987.06987.3 1.35E-06 Oct-52 K.IYPSRDEYEAHQER.V "sp|Q99496|RING2_HUMAN,tr|X6RFN3|X6RFN3_HUMAN" 2 1791.8176 1.32 140065 6987 3 1791.818408 598.2798 E3 ubiquitin-protein ligase RING2 OS=Homo sapiens OX=9606 GN=RNF2 PE=1 SV=1 4.83 1720.7 - 247252 - - - 0.4364 - 1.925 0.524 - 84.7 1 2 1 0.0008 14 0 0 0 2.64E+07 2.01E+07 - - - 6.1224 0.9999 221125_WJC_METTL3_EV_vs_WT_F10.06996.06996.3 4.16E-07 14/60 K.EDLRPSAPQQEGEASK.E sp|O76070|SYUG_HUMAN 1 1740.8279 3.23 140070 6996 3 1740.831025 581.2832 Gamma-synuclein OS=Homo sapiens OX=9606 GN=SNCG PE=1 SV=2 4.41 1721.9 - 534085 - - - 1.8204 - 2.372 0.509 - 221.4 1 2 0 0.0032 16 0 0 0 4.25E+07 1.32E+07 - - - 6.4302 1 221125_WJC_METTL3_EV_vs_WT_F10.06997.06997.3 4.91E-07 18/56 R.HLAMHAASSGDLSC[160.03]K.V sp|Q9UPG8|PLAL2_HUMAN 1 1583.7184 0.29 140071 6997 3 1583.717464 528.9134 Zinc finger protein PLAGL2 OS=Homo sapiens OX=9606 GN=PLAGL2 PE=1 SV=1 6.91 1722 - 274955 - - - -0.6201 - 3.365 0.65 - 339.5 1 2 0 -0.001 15 0 0 0 6.95E+06 2.38E+07 - - - 8.9529 0.9995 221125_WJC_METTL3_EV_vs_WT_F10.07000.07000.2 0.000794 28-Aug K.DQEPKPSPEPAAVSR.G sp|Q9H7S9|ZN703_HUMAN 1 1606.7951 1.88 140074 7000 2 1606.791546 804.4048 Zinc finger protein 703 OS=Homo sapiens OX=9606 GN=ZNF703 PE=1 SV=1 4.68 1722.4 - 133799 - - - -2.2119 - 1.501 0.536 - 121.4 1 2 0 -0.0036 15 0 0 0 3.05E+07 1.62E+07 - - - 3.9973 0.9965 221125_WJC_METTL3_EV_vs_WT_F10.07004.07004.3 0.000634 Nov-52 K.IYPSR[166.11]DEYEAHQER[166.11].V "sp|Q99496|RING2_HUMAN,tr|X6RFN3|X6RFN3_HUMAN" 2 1811.8342 1.28 140076 7004 3 1811.833416 604.952 E3 ubiquitin-protein ligase RING2 OS=Homo sapiens OX=9606 GN=RNF2 PE=1 SV=1 4.83 1722.9 - 755571 - - - -0.4139 - 1.562 0.339 - 103.3 1 2 1 -0.0008 14 0 0 0 2.66E+07 2.07E+07 - - - 3.5045 1 221125_WJC_METTL3_EV_vs_WT_F10.07007.07007.2 2.29E-09 Dec-32 R.QDDGSSSASPSVQGAPR.E "sp|Q9NQA3|WASH6_HUMAN,tr|A0A7I2YQU6|A0A7I2YQU6_HUMAN" 2 1644.734 1.43 140079 7007 2 1644.734148 823.3743 WAS protein family homolog 6 OS=Homo sapiens OX=9606 GN=WASH6P PE=1 SV=3 4.21 1723.3 - 199143 - - - 0.1167 - 2.805 0.742 - 330.1 1 2 0 0.0002 17 0 0 0 3.92E+07 2.74E+07 - - - 7.0571 0.9998 221125_WJC_METTL3_EV_vs_WT_F10.07008.07008.2 3.02E-05 28-Sep K.DQEPK[136.11]PSPEPAAVSR[166.11].G sp|Q9H7S9|ZN703_HUMAN 1 1624.8176 1.88 140080 7008 2 1624.815137 813.4161 Zinc finger protein 703 OS=Homo sapiens OX=9606 GN=ZNF703 PE=1 SV=1 4.68 1723.4 - 193310 - - - -1.4974 - 1.715 0.582 - 142.1 1 2 0 -0.0024 15 0 0 0 3.05E+07 1.62E+07 - - - 4.6651 1 221125_WJC_METTL3_EV_vs_WT_F10.07009.07009.2 0.000201 Nov-32 R.QDDGSSSASPSVQGAPR[166.11].E "sp|Q9NQA3|WASH6_HUMAN,tr|A0A7I2YQU6|A0A7I2YQU6_HUMAN" 2 1654.7422 1.43 140081 7009 2 1654.742669 828.3784 WAS protein family homolog 6 OS=Homo sapiens OX=9606 GN=WASH6P PE=1 SV=3 4.21 1723.6 - 149597 - - - 0.2677 - 2.612 0.671 - 293.8 1 2 0 0.0004 17 0 0 0 3.92E+07 2.74E+07 - - - 6.3574 0.9999 221125_WJC_METTL3_EV_vs_WT_F10.07014.07014.3 0.0003 18/60 R.NSVTPLASPEPTKKPR.L "sp|Q16875|F263_HUMAN,tr|A0A1W2PR17|A0A1W2PR17_HUMAN,tr|Q9H178|Q9H178_HUMAN,tr|Q5W015|Q5W015_HUMAN,tr|Q5VX20|Q5VX20_HUMAN" 5 1720.9472 3.76 140084 7014 3 1720.949711 574.6563 "6-phosphofructo-2-kinase\fructose-2,6-bisphosphatase 3 OS=Homo sapiens OX=9606 GN=PFKFB3 PE=1 SV=1" 9.99 1724.2 - 411488 - - - 1.4684 - 3.475 0.526 - 560.4 1 2 1 0.0025 16 0 0 0 4.92E+07 1.31E+07 - - - 7.5997 0.9999 221125_WJC_METTL3_EV_vs_WT_F10.07017.07017.4 9.42E-07 22/90 R.NSVTPLASPEPTKKPR.L "sp|Q16875|F263_HUMAN,tr|A0A1W2PR17|A0A1W2PR17_HUMAN,tr|Q9H178|Q9H178_HUMAN,tr|Q5W015|Q5W015_HUMAN,tr|Q5VX20|Q5VX20_HUMAN" 5 1720.9472 3.3 140085 7017 4 1720.946788 431.2441 "6-phosphofructo-2-kinase\fructose-2,6-bisphosphatase 3 OS=Homo sapiens OX=9606 GN=PFKFB3 PE=1 SV=1" 9.99 1724.6 - 612237 - - - -0.2301 - 3.495 0.531 - 344 1 2 1 -0.0004 16 0 0 0 5.21E+07 1.58E+07 - - - 4.2885 0.9975 221125_WJC_METTL3_EV_vs_WT_F10.07025.07025.3 0.00273 16/44 R.SATREPPYRVPR.D "sp|P43243|MATR3_HUMAN,tr|A8MXP9|A8MXP9_HUMAN,tr|D6R991|D6R991_HUMAN,tr|A0A0R4J2E8|A0A0R4J2E8_HUMAN,tr|D6REM6|D6REM6_HUMAN" 5 1427.7633 1.09 140091 7025 3 1427.764306 476.9284 Matrin-3 OS=Homo sapiens OX=9606 GN=MATR3 PE=1 SV=2 10.74 1725.6 - 3.45E+06 - - - 0.6724 - 1.851 0.314 - 220.1 1 2 2 0.001 12 0 0 0 3.79E+08 3.48E+08 - - - 3.7472 1 221125_WJC_METTL3_EV_vs_WT_F10.07029.07029.3 1.68E-09 15/64 R.QDDGSSSASPSVQGAPR.E "sp|Q9NQA3|WASH6_HUMAN,tr|A0A7I2YQU6|A0A7I2YQU6_HUMAN" 2 1644.734 1.7 140093 7029 3 1644.732519 549.2519 WAS protein family homolog 6 OS=Homo sapiens OX=9606 GN=WASH6P PE=1 SV=3 4.21 1726.1 - 611433 - - - -0.8737 - 2.377 0.561 - 314.4 1 2 0 -0.0014 17 0 0 0 2.03E+07 1.20E+07 - - - 6.9816 0.9999 221125_WJC_METTL3_EV_vs_WT_F10.07031.07031.4 2.17E-05 16/90 R.WATHGEPSPVNSHPQR.S "sp|Q06210|GFPT1_HUMAN,tr|A0A6I8PRN4|A0A6I8PRN4_HUMAN,tr|A0A6I8PTT9|A0A6I8PTT9_HUMAN" 3 1798.8499 1.35 140094 7031 4 1798.853293 450.7198 Glutamine--fructose-6-phosphate aminotransferase [isomerizing] 1 OS=Homo sapiens OX=9606 GN=GFPT1 PE=1 SV=3 6.92 1726.4 - 818127 - - - 1.8701 - 2.739 0.49 - 168.5 1 2 0 0.0034 16 0 0 0 5.38E+07 3.99E+07 - - - 3.845 0.9999 221125_WJC_METTL3_EV_vs_WT_F10.07034.07034.3 0.000186 Nov-56 R.ENQELNAHNQELNNR[166.11].L "sp|Q6WCQ1|MPRIP_HUMAN,tr|A0A494BZV2|A0A494BZV2_HUMAN,tr|H0Y7E2|H0Y7E2_HUMAN,tr|H0Y2S9|H0Y2S9_HUMAN,tr|J3KSW8|J3KSW8_HUMAN" 5 1831.8437 0.78 140097 7034 3 1831.843554 611.6218 Myosin phosphatase Rho-interacting protein OS=Homo sapiens OX=9606 GN=MPRIP PE=1 SV=3 4.75 1726.8 - 203868 - - - -0.0639 - 1.901 0.462 - 40.7 1 2 0 -0.0001 15 0 0 0 6.60E+06 8.44E+06 - - - 5.367 0.9997 221125_WJC_METTL3_EV_vs_WT_F10.07035.07035.2 0.000353 28-May R.DSGFSSGNTDTSSER[166.11].G sp|Q9NYL2|M3K20_HUMAN 1 1555.6262 0.62 140098 7035 2 1555.625955 778.8204 Mitogen-activated protein kinase kinase kinase 20 OS=Homo sapiens OX=9606 GN=MAP3K20 PE=1 SV=3 4.03 1726.9 - 76765.6 - - - -0.153 - 1.154 0.552 - 50.7 1 2 0 -0.0002 15 0 0 0 1.30E+06 2.11E+06 - - - 3.4701 1 221125_WJC_METTL3_EV_vs_WT_F10.07038.07038.2 1.21E-08 15/22 K.SKAEAESLYQSK.Y sp|P04264|K2C1_HUMAN 1 1339.662 999 140099 7038 2 1339.662088 670.8383 "Keratin, type II cytoskeletal 1 OS=Homo sapiens OX=9606 GN=KRT1 PE=1 SV=6" 5.86 1727.3 - 339252 - - - 0.0955 - 2.822 0.605 - 610.9 1 2 1 0.0001 12 0 0 0 4.51E+07 0.00E+00 - - - 6.2392 0.9916 221125_WJC_METTL3_EV_vs_WT_F10.07046.07046.3 0.00628 16/60 R.WATHGEPSPVNSHPQR.S "sp|Q06210|GFPT1_HUMAN,tr|A0A6I8PRN4|A0A6I8PRN4_HUMAN,tr|A0A6I8PTT9|A0A6I8PTT9_HUMAN" 3 1798.8499 1.64 140104 7046 3 1798.854797 600.6239 Glutamine--fructose-6-phosphate aminotransferase [isomerizing] 1 OS=Homo sapiens OX=9606 GN=GFPT1 PE=1 SV=3 6.92 1728.3 - 247721 - - - 2.7062 - 1.515 0.271 - 43.5 1 2 0 0.0049 16 0 0 0 2.09E+07 1.27E+07 - - - 2.6259 0.9994 221125_WJC_METTL3_EV_vs_WT_F10.07050.07050.3 0.0108 Aug-60 K.EDLR[166.11]PSAPQQEGEASK[136.11].E sp|O76070|SYUG_HUMAN 1 1758.8503 3.23 140105 7050 3 1758.851023 587.2907 Gamma-synuclein OS=Homo sapiens OX=9606 GN=SNCG PE=1 SV=2 4.41 1728.9 - 359822 - - - 0.3963 - 1.747 0.336 - 73.3 1 2 0 0.0007 16 0 0 0 4.25E+07 1.32E+07 - - - 3.7174 0.9999 221125_WJC_METTL3_EV_vs_WT_F10.07054.07054.3 1.93E-06 15/60 R.NSVTPLASPEPTK[136.11]K[136.11]PR[166.11].L "sp|Q16875|F263_HUMAN,tr|A0A1W2PR17|A0A1W2PR17_HUMAN,tr|Q9H178|Q9H178_HUMAN,tr|Q5W015|Q5W015_HUMAN,tr|Q5VX20|Q5VX20_HUMAN" 5 1746.9839 3.76 140107 7054 3 1746.985816 583.3352 "6-phosphofructo-2-kinase\fructose-2,6-bisphosphatase 3 OS=Homo sapiens OX=9606 GN=PFKFB3 PE=1 SV=1" 9.99 1729.3 - 378151 - - - 1.1231 - 3.573 0.587 - 374.9 1 2 1 0.002 16 0 0 0 4.92E+07 1.31E+07 - - - 8.3513 0.9547 221125_WJC_METTL3_EV_vs_WT_F10.07062.07062.3 0.00402 14/40 S.ATR[166.11]EPPYR[166.11]VPR[166.11].D "sp|P43243|MATR3_HUMAN,tr|A8MXP9|A8MXP9_HUMAN,tr|D6R991|D6R991_HUMAN,tr|A0A0R4J2E8|A0A0R4J2E8_HUMAN,tr|D6REM6|D6REM6_HUMAN" 5 1370.7561 1.89 140110 7062 3 1370.758062 457.926 Matrin-3 OS=Homo sapiens OX=9606 GN=MATR3 PE=1 SV=2 10.74 1730.5 - 509646 - - - 1.4116 - 2.723 0.371 - 236.5 1 1 2 0.0019 11 0 0 0 6.30E+07 3.33E+07 - - - 5.5215 0.9742 221125_WJC_METTL3_EV_vs_WT_F10.07068.07068.2 1.29E-05 26-Aug Y.SHGSQETDEEFDAR[166.11].W "sp|P20674|COX5A_HUMAN,tr|H3BNX8|H3BNX8_HUMAN,tr|H3BRI0|H3BRI0_HUMAN" 3 1616.6578 2.14 140111 7068 2 1616.661056 809.3362 "Cytochrome c oxidase subunit 5A, mitochondrial OS=Homo sapiens OX=9606 GN=COX5A PE=1 SV=2" 4.17 1731.5 - 112318 - - - 1.9967 - 1.789 0.494 - 156.5 1 1 0 0.0032 14 0 0 0 3.33E+07 1.56E+07 - - - 4.1483 0.9961 221125_WJC_METTL3_EV_vs_WT_F10.07070.07070.3 0.023 16/36 R.R[166.11]R[166.11]EEEGIQLR[166.11].K "sp|O60684|IMA7_HUMAN,sp|O15131|IMA6_HUMAN,sp|P52294|IMA5_HUMAN,tr|C9JWD9|C9JWD9_HUMAN,tr|S4R3E5|S4R3E5_HUMAN,tr|C9JYI4|C9JYI4_HUMAN,tr|C9J352|C9J352_HUMAN,tr|C9J4U1|C9J4U1_HUMAN,tr|F2Z3G4|F2Z3G4_HUMAN,tr|Q5TD90|Q5TD90_HUMAN" 10 1314.7147 0.79 140112 7070 3 1314.713489 439.2455 Importin subunit alpha-7 OS=Homo sapiens OX=9606 GN=KPNA6 PE=1 SV=1 6.23 1731.7 - 484141 - - - -0.8884 - 2 0.256 - 328.6 1 2 1 -0.0012 10 0 0 0 1.84E+07 2.32E+07 - - - 3.4181 1 221125_WJC_METTL3_EV_vs_WT_F10.07075.07075.3 3.05E-10 16/52 Y.SHGSQETDEEFDAR[166.11].W "sp|P20674|COX5A_HUMAN,tr|H3BNX8|H3BNX8_HUMAN,tr|H3BRI0|H3BRI0_HUMAN" 3 1616.6578 2.12 140114 7075 3 1616.658411 539.8932 "Cytochrome c oxidase subunit 5A, mitochondrial OS=Homo sapiens OX=9606 GN=COX5A PE=1 SV=2" 4.17 1732.3 - 4.08E+06 - - - 0.3606 - 3.264 0.698 - 372.4 1 1 0 0.0006 14 0 0 0 6.53E+08 3.08E+08 - - - 9.4656 0.9563 221125_WJC_METTL3_EV_vs_WT_F10.07076.07076.3 0.000295 15/36 A.TR[166.11]EPPYR[166.11]VPR[166.11].D "sp|P43243|MATR3_HUMAN,tr|A8MXP9|A8MXP9_HUMAN,tr|D6R991|D6R991_HUMAN,tr|A0A0R4J2E8|A0A0R4J2E8_HUMAN,tr|D6REM6|D6REM6_HUMAN" 5 1299.719 1.17 140115 7076 3 1299.719502 434.2469 Matrin-3 OS=Homo sapiens OX=9606 GN=MATR3 PE=1 SV=2 10.74 1732.4 - 439893 - - - 0.3755 - 2.506 0.361 - 245.1 1 1 2 0.0005 10 0 0 0 2.80E+07 2.39E+07 - - - 5.2476 1 221125_WJC_METTL3_EV_vs_WT_F10.07077.07077.3 2.04E-05 16/52 K.HGVDVEVQGPHEAR.D "sp|Q9HCE1|MOV10_HUMAN,tr|Q5JR04|Q5JR04_HUMAN" 2 1528.7383 1.48 140116 7077 3 1528.741087 510.5867 Helicase MOV-10 OS=Homo sapiens OX=9606 GN=MOV10 PE=1 SV=2 5.27 1732.6 - 398538 - - - 1.8538 - 2.672 0.549 - 366.4 1 2 0 0.0028 14 0 0 0 3.94E+07 2.66E+07 - - - 7.2719 1 221125_WJC_METTL3_EV_vs_WT_F10.07083.07083.2 0.00708 19/26 Y.SHGSQETDEEFDAR.W "sp|P20674|COX5A_HUMAN,tr|H3BNX8|H3BNX8_HUMAN,tr|H3BRI0|H3BRI0_HUMAN" 3 1606.6496 2.14 140119 7083 2 1606.652732 804.3321 "Cytochrome c oxidase subunit 5A, mitochondrial OS=Homo sapiens OX=9606 GN=COX5A PE=1 SV=2" 4.17 1733.3 - 548501 - - - 1.9755 - 2.887 0.614 - 964.8 1 1 0 0.0032 14 0 0 0 3.33E+07 1.56E+07 - - - 6.2356 0.9953 221125_WJC_METTL3_EV_vs_WT_F10.07085.07085.3 1.52E-06 15/52 Y.SHGSQETDEEFDAR.W "sp|P20674|COX5A_HUMAN,tr|H3BNX8|H3BNX8_HUMAN,tr|H3BRI0|H3BRI0_HUMAN" 3 1606.6496 2.12 140121 7085 3 1606.653354 536.5571 "Cytochrome c oxidase subunit 5A, mitochondrial OS=Homo sapiens OX=9606 GN=COX5A PE=1 SV=2" 4.17 1733.5 - 1.17E+07 - - - 2.3627 - 2.959 0.519 - 355.9 1 1 0 0.0038 14 0 0 0 6.53E+08 3.08E+08 - - - 7.2083 0.9986 221125_WJC_METTL3_EV_vs_WT_F10.07094.07094.3 0.00209 Dec-44 K.GR[166.11]DDITVHDNIK[136.11].Y "sp|Q5VSG8|MANEL_HUMAN,tr|E9PMU5|E9PMU5_HUMAN" 2 1399.7175 2.31 140128 7094 3 1399.716085 467.5798 "Glycoprotein endo-alpha-1,2-mannosidase-like protein OS=Homo sapiens OX=9606 GN=MANEAL PE=2 SV=1" 5.3 1734.6 - 424656 - - - -0.9838 - 1.708 0.375 - 220.2 1 2 1 -0.0014 12 0 0 0 1.85E+07 8.01E+06 - - - 4.2043 0.9995 221125_WJC_METTL3_EV_vs_WT_F10.07099.07099.3 0.000344 Jun-84 K.AENSAALGK[136.11]PTAGTTDAGEAAK[136.11].L sp|Q96T17|MA7D2_HUMAN 1 2046.02 0.6 140133 7099 3 2046.019565 683.014 MAP7 domain-containing protein 2 OS=Homo sapiens OX=9606 GN=MAP7D2 PE=1 SV=2 4.68 1735.3 - 96220.5 - - - -0.2258 - 1.792 0.379 - 22.1 6 2 0 -0.0005 22 0 0 0 9.19E+06 1.54E+07 - - - 3.7882 0.9997 221125_WJC_METTL3_EV_vs_WT_F10.07103.07103.3 1.93E-05 Sep-84 K.AENSAALGKPTAGTTDAGEAAK.L sp|Q96T17|MA7D2_HUMAN 1 2029.9916 0.6 140135 7103 3 2029.996809 677.6712 MAP7 domain-containing protein 2 OS=Homo sapiens OX=9606 GN=MAP7D2 PE=1 SV=2 4.68 1735.8 - 122013 - - - 2.5527 - 1.776 0.47 - 62.6 1 2 0 0.0052 22 0 0 0 9.19E+06 1.54E+07 - - - 5.1403 1 221125_WJC_METTL3_EV_vs_WT_F10.07115.07115.4 0.000147 15/78 K.HGVDVEVQGPHEAR.D "sp|Q9HCE1|MOV10_HUMAN,tr|Q5JR04|Q5JR04_HUMAN" 2 1528.7383 1.39 140139 7115 4 1528.739777 383.1918 Helicase MOV-10 OS=Homo sapiens OX=9606 GN=MOV10 PE=1 SV=2 5.27 1737.3 - 206136 - - - 0.9969 - 2.324 0.493 - 204.7 1 2 0 0.0015 14 0 0 0 9.80E+06 7.05E+06 - - - 3.8236 0.9998 221125_WJC_METTL3_EV_vs_WT_F10.07124.07124.3 0.000433 Oct-52 K.SDSGK[136.11]PYYYNSQTK[136.11].E "sp|O75400|PR40A_HUMAN,tr|F5H578|F5H578_HUMAN,tr|H0YG38|H0YG38_HUMAN,tr|A0A7N4I394|A0A7N4I394_HUMAN,tr|H7C2N3|H7C2N3_HUMAN" 5 1652.7653 1.11 140143 7124 3 1652.768962 551.929 Pre-mRNA-processing factor 40 homolog A OS=Homo sapiens OX=9606 GN=PRPF40A PE=1 SV=2 8.1 1738.5 - 401892 - - - 2.206 - 1.954 0.456 - 98.9 1 2 0 0.0036 14 0 0 0 3.42E+07 3.07E+07 - - - 5.4032 0.9673 221125_WJC_METTL3_EV_vs_WT_F10.07125.07125.3 245 0/64 K.DLDEMDDDDDDDDVGDH.D "sp|Q15029|U5S1_HUMAN,tr|K7EIV5|K7EIV5_HUMAN,tr|K7EIT3|K7EIT3_HUMAN" 3 1949.6229 - 140144 7125 3 1949.622448 650.8816 116 kDa U5 small nuclear ribonucleoprotein component OS=Homo sapiens OX=9606 GN=EFTUD2 PE=1 SV=1 3.28 1738.6 - 164940 - - - -0.2165 - 0.223 0.845 - 0 1 1 0 -0.0004 17 0 0 0 - - - - - 4.1699 0.9998 221125_WJC_METTL3_EV_vs_WT_F10.07129.07129.3 0.000361 14/40 K.LK[136.11]GDDLQAIK[136.11]K[136.11].E "sp|P07910|HNRPC_HUMAN,tr|B4DY08|B4DY08_HUMAN,tr|G3V5V7|G3V5V7_HUMAN,tr|B2R5W2|B2R5W2_HUMAN,tr|G3V4C1|G3V4C1_HUMAN,tr|G3V576|G3V576_HUMAN,tr|G3V2D6|G3V2D6_HUMAN,tr|G3V4W0|G3V4W0_HUMAN,tr|G3V2Q1|G3V2Q1_HUMAN" 9 1251.7613 1.39 140145 7129 3 1251.761951 418.261 Heterogeneous nuclear ribonucleoproteins C1\C2 OS=Homo sapiens OX=9606 GN=HNRNPC PE=1 SV=4 8.5 1739.1 - 2.95E+06 - - - 0.5305 - 2.39 0.448 - 160.5 1 2 1 0.0007 11 0 0 0 1.14E+08 8.21E+07 - - - 6.0098 0.9988 221125_WJC_METTL3_EV_vs_WT_F10.07130.07130.2 0.00518 20-May K.ENAGEDPGLAR.Q sp|P81605|DCD_HUMAN 1 1127.5207 999 140146 7130 2 1127.522686 564.7676 Dermcidin OS=Homo sapiens OX=9606 GN=DCD PE=1 SV=2 4.14 1739.2 - 206727 - - - 1.7472 - 1.239 0.437 - 59.9 1 2 0 0.002 11 0 0 0 5.41E+06 0.00E+00 - - - 2.8478 0.9999 221125_WJC_METTL3_EV_vs_WT_F10.07134.07134.3 2.49E-05 15/52 R.TSKEPPSSPLQPQK.E "sp|Q92615|LAR4B_HUMAN,tr|A0A087X183|A0A087X183_HUMAN,tr|H0Y4V9|H0Y4V9_HUMAN" 3 1522.7991 1.57 140149 7134 3 1522.800539 508.607 La-related protein 4B OS=Homo sapiens OX=9606 GN=LARP4B PE=1 SV=3 8.26 1739.7 - 939045 - - - 0.9305 - 2.479 0.533 - 186.6 1 2 1 0.0014 14 0 0 0 6.23E+07 3.97E+07 - - - 6.8947 0.9999 221125_WJC_METTL3_EV_vs_WT_F10.07136.07136.3 0.000227 Nov-52 K.SDSGKPYYYNSQTK.E "sp|O75400|PR40A_HUMAN,tr|F5H578|F5H578_HUMAN,tr|H0YG38|H0YG38_HUMAN,tr|A0A7N4I394|A0A7N4I394_HUMAN,tr|H7C2N3|H7C2N3_HUMAN" 5 1636.7369 1.11 140150 7136 3 1636.739212 546.5862 Pre-mRNA-processing factor 40 homolog A OS=Homo sapiens OX=9606 GN=PRPF40A PE=1 SV=2 8.1 1739.9 - 678366 - - - 1.4028 - 1.977 0.482 - 121.5 1 2 0 0.0023 14 0 0 0 3.42E+07 3.07E+07 - - - 5.7245 0.992 221125_WJC_METTL3_EV_vs_WT_F10.07145.07145.3 0.0106 Aug-52 R.K[136.11]IEQVDK[136.11]EDEITEK[136.11].K sp|Q9Y2X3|NOP58_HUMAN 1 1726.9051 1 140153 7145 3 1726.909541 576.6423 Nucleolar protein 58 OS=Homo sapiens OX=9606 GN=NOP58 PE=1 SV=1 4.36 1741.2 - 164088 - - - 2.5653 - 1.462 0.369 - 71.5 1 2 1 0.0044 14 0 0 0 2.87E+07 2.87E+07 - - - 3.6621 0.9988 221125_WJC_METTL3_EV_vs_WT_F10.07147.07147.3 0.000253 13/44 R.SATR[166.11]EPPYR[166.11]VPR[166.11].D "sp|P43243|MATR3_HUMAN,tr|A8MXP9|A8MXP9_HUMAN,tr|D6R991|D6R991_HUMAN,tr|A0A0R4J2E8|A0A0R4J2E8_HUMAN,tr|D6REM6|D6REM6_HUMAN" 5 1457.7882 1.09 140154 7147 3 1457.791125 486.9367 Matrin-3 OS=Homo sapiens OX=9606 GN=MATR3 PE=1 SV=2 10.74 1741.5 - 2.35E+06 - - - 2.0366 - 2.238 0.372 - 161.3 1 2 2 0.003 12 0 0 0 3.79E+08 3.47E+08 - - - 4.9196 0.9981 221125_WJC_METTL3_EV_vs_WT_F10.07163.07163.3 0.00986 Sep-56 K.K[136.11]QLAVAEGK[136.11]PPEAPK[136.11].G "sp|P56192|SYMC_HUMAN,tr|H0YIP0|H0YIP0_HUMAN" 2 1585.9254 1 140163 7163 3 1585.928712 529.6491 "Methionine--tRNA ligase, cytoplasmic OS=Homo sapiens OX=9606 GN=MARS1 PE=1 SV=2" 8.5 1743.5 - 182210 - - - 2.0934 - 1.447 0.346 - 69.8 1 2 0 0.0033 15 0 0 0 7.82E+06 7.83E+06 - - - 3.3608 0.9987 221125_WJC_METTL3_EV_vs_WT_F10.07167.07167.4 0.00696 14/78 K.AVVVC[160.03]PK[136.11]DEDYK[136.11]QR[166.11].T "sp|Q00839|HNRPU_HUMAN,tr|A0A1W2PQL0|A0A1W2PQL0_HUMAN,tr|A0A1W2PPL4|A0A1W2PPL4_HUMAN,tr|A0A1W2PQ74|A0A1W2PQ74_HUMAN,tr|Q5RI18|Q5RI18_HUMAN,tr|A0A1W2PP35|A0A1W2PP35_HUMAN,tr|A0A1W2PPS1|A0A1W2PPS1_HUMAN,tr|A0A1W2PRZ7|A0A1W2PRZ7_HUMAN,tr|A0A1W2PPH7|A0A1W2PPH7_HUMAN,tr|A0A1W2PQD4|A0A1W2PQD4_HUMAN,tr|A0A1W2PP34|A0A1W2PP34_HUMAN,tr|A0A1X7SBS1|A0A1X7SBS1_HUMAN" 12 1731.8824 0.9 140165 7167 4 1731.884052 433.9779 Heterogeneous nuclear ribonucleoprotein U OS=Homo sapiens OX=9606 GN=HNRNPU PE=1 SV=6 6.16 1744.1 - 221024 - - - 0.9394 - 2.564 0.344 - 98.9 1 2 2 0.0016 14 0 0 0 2.89E+07 3.21E+07 - - - 2.5624 1 221125_WJC_METTL3_EV_vs_WT_F10.07183.07183.3 3.84E-06 20/52 R.KIEQVDKEDEITEK.K sp|Q9Y2X3|NOP58_HUMAN 1 1702.8625 1 140172 7183 3 1702.864799 568.6281 Nucleolar protein 58 OS=Homo sapiens OX=9606 GN=NOP58 PE=1 SV=1 4.36 1746.3 - 1.00E+06 - - - 1.3436 - 3.673 0.633 - 487.4 1 2 1 0.0023 14 0 0 0 2.87E+07 2.87E+07 - - - 9.0542 0.9999 221125_WJC_METTL3_EV_vs_WT_F10.07201.07201.3 1.35E-06 13/56 K.DQEPK[136.11]PSPEPAAVSR[166.11].G sp|Q9H7S9|ZN703_HUMAN 1 1624.8176 1.85 140181 7201 3 1624.821276 542.6131 Zinc finger protein 703 OS=Homo sapiens OX=9606 GN=ZNF703 PE=1 SV=1 4.68 1748.7 - 328737 - - - 2.2809 - 2.414 0.512 - 214.9 1 2 0 0.0037 15 0 0 0 8.68E+08 4.69E+08 - - - 6.5469 0.9999 221125_WJC_METTL3_EV_vs_WT_F10.07214.07214.3 2.70E-06 20/52 K.AVVVC[160.03]PK[136.11]DEDYK[136.11]QR[166.11].T "sp|Q00839|HNRPU_HUMAN,tr|A0A1W2PQL0|A0A1W2PQL0_HUMAN,tr|A0A1W2PPL4|A0A1W2PPL4_HUMAN,tr|A0A1W2PQ74|A0A1W2PQ74_HUMAN,tr|Q5RI18|Q5RI18_HUMAN,tr|A0A1W2PP35|A0A1W2PP35_HUMAN,tr|A0A1W2PPS1|A0A1W2PPS1_HUMAN,tr|A0A1W2PRZ7|A0A1W2PRZ7_HUMAN,tr|A0A1W2PPH7|A0A1W2PPH7_HUMAN,tr|A0A1W2PQD4|A0A1W2PQD4_HUMAN,tr|A0A1W2PP34|A0A1W2PP34_HUMAN,tr|A0A1X7SBS1|A0A1X7SBS1_HUMAN" 12 1731.8824 0.93 140187 7214 3 1731.885537 578.3014 Heterogeneous nuclear ribonucleoprotein U OS=Homo sapiens OX=9606 GN=HNRNPU PE=1 SV=6 6.16 1750.3 - 395189 - - - 1.7969 - 3.462 0.573 - 673 1 2 2 0.0031 14 0 0 0 1.47E+07 1.57E+07 - - - 8.2278 0.9997 221125_WJC_METTL3_EV_vs_WT_F10.07216.07216.3 0.000864 Nov-56 K.DQEPKPSPEPAAVSR.G sp|Q9H7S9|ZN703_HUMAN 1 1606.7951 1.85 140188 7216 3 1606.795137 536.6056 Zinc finger protein 703 OS=Homo sapiens OX=9606 GN=ZNF703 PE=1 SV=1 4.68 1750.5 - 593111 - - - 0.023 - 1.906 0.358 - 142.7 1 2 0 0 15 0 0 0 8.68E+08 4.69E+08 - - - 4.2144 0.8218 221125_WJC_METTL3_EV_vs_WT_F10.07221.07221.3 0.00125 Sep-52 R.QSEVPK[136.11]PEDGEPPR[166.11].R "sp|Q9Y520|PRC2C_HUMAN,tr|E7EPN9|E7EPN9_HUMAN" 2 1581.7754 0.86 140192 7221 3 1581.783563 528.2657 Protein PRRC2C OS=Homo sapiens OX=9606 GN=PRRC2C PE=1 SV=4 4.41 1751.1 - 321147 - - - 5.1796 - 1.763 0.151 - 80.4 1 2 0 0.0082 14 0 0 0 4.75E+06 5.53E+06 - - - 1.7281 0.9999 221125_WJC_METTL3_EV_vs_WT_F10.07227.07227.3 7.87E-07 13/36 R.K[136.11]GTFTDDLHK[136.11].L "sp|Q9H4A3|WNK1_HUMAN,sp|Q9Y3S1|WNK2_HUMAN,tr|F5GWT4|F5GWT4_HUMAN,tr|H0Y7J9|H0Y7J9_HUMAN,tr|A0A6Q8PFM0|A0A6Q8PFM0_HUMAN,tr|H0Y493|H0Y493_HUMAN,tr|F8W9F9|F8W9F9_HUMAN,tr|H0Y7R3|H0Y7R3_HUMAN,tr|H0Y7T5|H0Y7T5_HUMAN" 9 1176.611 1.56 140196 7227 3 1176.61329 393.2109 Serine\threonine-protein kinase WNK1 OS=Homo sapiens OX=9606 GN=WNK1 PE=1 SV=2 6.75 1751.9 - 542830 - - - 1.9565 - 2.203 0.456 - 235.4 1 2 0 0.0023 10 0 0 0 1.80E+07 1.15E+07 - - - 5.9299 0.9211 221125_WJC_METTL3_EV_vs_WT_F10.07229.07229.3 0.0642 Sep-48 R.LRLEEEQKEEEER.K "sp|Q96HY6|DDRGK_HUMAN,tr|A0A0A0MRX2|A0A0A0MRX2_HUMAN" 2 1715.8326 1.39 140198 7229 3 1715.83662 572.9515 DDRGK domain-containing protein 1 OS=Homo sapiens OX=9606 GN=DDRGK1 PE=1 SV=2 4.36 1752.1 - 186130 - - - 2.3388 - 2.079 0.13 - 126.3 1 2 2 0.004 13 0 0 0 1.07E+07 7.68E+06 - - - 1.9726 1 221125_WJC_METTL3_EV_vs_WT_F10.07233.07233.2 1.62E-08 26-Nov R.NVIHASDSVEGAQR.E "sp|O00746|NDKM_HUMAN,tr|Q4TT34|Q4TT34_HUMAN,tr|A0A087WVT9|A0A087WVT9_HUMAN,tr|F2Z2X0|F2Z2X0_HUMAN" 4 1481.7223 2.63 140202 7233 2 1481.724702 741.8684 "Nucleoside diphosphate kinase, mitochondrial OS=Homo sapiens OX=9606 GN=NME4 PE=1 SV=1" 5.32 1752.6 - 86706.4 - - - 1.642 - 2.399 0.686 - 408 1 2 0 0.0024 14 0 0 0 4.68E+06 1.78E+06 - - - 6.3029 0.9999 221125_WJC_METTL3_EV_vs_WT_F10.07237.07237.3 0.000387 13/52 R.NVIHASDSVEGAQR.E "sp|O00746|NDKM_HUMAN,tr|Q4TT34|Q4TT34_HUMAN,tr|A0A087WVT9|A0A087WVT9_HUMAN,tr|F2Z2X0|F2Z2X0_HUMAN" 4 1481.7223 2.08 140204 7237 3 1481.726331 494.9147 "Nucleoside diphosphate kinase, mitochondrial OS=Homo sapiens OX=9606 GN=NME4 PE=1 SV=1" 5.32 1753.2 - 1.81E+06 - - - 2.7414 - 2.339 0.52 - 163 1 2 0 0.0041 14 0 0 0 4.40E+07 2.11E+07 - - - 6.5945 0.9867 221125_WJC_METTL3_EV_vs_WT_F10.07238.07238.3 0.0553 Sep-52 R.AHQITDESLESTR[166.11]R[166.11].L "sp|O00161|SNP23_HUMAN,tr|H3BNG6|H3BNG6_HUMAN,tr|H3BNE1|H3BNE1_HUMAN,tr|H3BR18|H3BR18_HUMAN,tr|H3BM38|H3BM38_HUMAN,tr|H3BU94|H3BU94_HUMAN,tr|H3BPJ0|H3BPJ0_HUMAN" 7 1661.8236 0.74 140205 7238 3 1661.831521 554.9485 Synaptosomal-associated protein 23 OS=Homo sapiens OX=9606 GN=SNAP23 PE=1 SV=1 5.45 1753.3 - 286408 - - - 4.7658 - 1.852 0.284 - 107.2 1 2 0 0.0079 14 0 0 0 6.30E+06 8.47E+06 - - - 3.3419 0.9992 221125_WJC_METTL3_EV_vs_WT_F10.07240.07240.4 0.000718 Nov-78 R.VRPDYTAQNLDHGK.A "sp|P82930|RT34_HUMAN,tr|C9JJ19|C9JJ19_HUMAN" 2 1612.7958 1.24 140207 7240 4 1612.800649 404.2062 "28S ribosomal protein S34, mitochondrial OS=Homo sapiens OX=9606 GN=MRPS34 PE=1 SV=2" 6.72 1753.6 - 357573 - - - 3.0264 - 1.968 0.372 - 90.3 1 2 0 0.0049 14 0 0 0 1.97E+08 1.59E+08 - - - 2.7089 0.9912 221125_WJC_METTL3_EV_vs_WT_F10.07241.07241.3 2.10E-06 Dec-48 R.LR[166.11]LEEEQK[136.11]EEEER[166.11].K "sp|Q96HY6|DDRGK_HUMAN,tr|A0A0A0MRX2|A0A0A0MRX2_HUMAN" 2 1743.8633 1.39 140208 7241 3 1743.863342 582.2951 DDRGK domain-containing protein 1 OS=Homo sapiens OX=9606 GN=DDRGK1 PE=1 SV=2 4.36 1753.7 - 202991 - - - -0.0029 - 2.588 0.156 - 272.2 1 2 2 0 13 0 0 0 1.07E+07 7.68E+06 - - - 2.8574 0.9996 221125_WJC_METTL3_EV_vs_WT_F10.07243.07243.2 0.000427 26-Sep R.NVIHASDSVEGAQR[166.11].E "sp|O00746|NDKM_HUMAN,tr|Q4TT34|Q4TT34_HUMAN,tr|A0A087WVT9|A0A087WVT9_HUMAN,tr|F2Z2X0|F2Z2X0_HUMAN" 4 1491.7305 2.63 140210 7243 2 1491.733479 746.8725 "Nucleoside diphosphate kinase, mitochondrial OS=Homo sapiens OX=9606 GN=NME4 PE=1 SV=1" 5.32 1754 - 70952.2 - - - 1.9709 - 2.111 0.457 - 271.5 1 2 0 0.0029 14 0 0 0 4.68E+06 1.78E+06 - - - 4.2904 0.9999 221125_WJC_METTL3_EV_vs_WT_F10.07248.07248.3 0.000219 Dec-52 R.NVIHASDSVEGAQR[166.11].E "sp|O00746|NDKM_HUMAN,tr|Q4TT34|Q4TT34_HUMAN,tr|A0A087WVT9|A0A087WVT9_HUMAN,tr|F2Z2X0|F2Z2X0_HUMAN" 4 1491.7305 2.08 140213 7248 3 1491.731981 498.2508 "Nucleoside diphosphate kinase, mitochondrial OS=Homo sapiens OX=9606 GN=NME4 PE=1 SV=1" 5.32 1754.6 - 1.18E+06 - - - 0.9667 - 2.107 0.403 - 189.4 1 2 0 0.0014 14 0 0 0 4.40E+07 2.11E+07 - - - 5.0132 0.9794 221125_WJC_METTL3_EV_vs_WT_F10.07249.07249.4 0.32 Nov-72 R.LRLEEEQKEEEER.K "sp|Q96HY6|DDRGK_HUMAN,tr|A0A0A0MRX2|A0A0A0MRX2_HUMAN" 2 1715.8326 1.34 140214 7249 4 1715.834497 429.9654 DDRGK domain-containing protein 1 OS=Homo sapiens OX=9606 GN=DDRGK1 PE=1 SV=2 4.36 1754.7 - 415027 - - - 1.1015 - 1.788 0.225 - 77.8 1 2 2 0.0019 13 0 0 0 8.87E+06 6.63E+06 - - - 1.3993 0.9999 221125_WJC_METTL3_EV_vs_WT_F10.07255.07255.3 3.42E-08 15/52 R.VR[166.11]PDYTAQNLDHGK[136.11].A "sp|P82930|RT34_HUMAN,tr|C9JJ19|C9JJ19_HUMAN" 2 1630.8182 1.22 140218 7255 3 1630.814348 544.6134 "28S ribosomal protein S34, mitochondrial OS=Homo sapiens OX=9606 GN=MRPS34 PE=1 SV=2" 6.72 1755.5 - 1.55E+06 - - - -2.3853 - 3.111 0.471 - 365.5 1 2 0 -0.0039 14 0 0 0 2.56E+08 2.10E+08 - - - 6.8063 0.9993 221125_WJC_METTL3_EV_vs_WT_F10.07258.07258.3 0.00139 Sep-52 R.AHQITDESLESTRR.L "sp|O00161|SNP23_HUMAN,tr|H3BNG6|H3BNG6_HUMAN,tr|H3BNE1|H3BNE1_HUMAN,tr|H3BR18|H3BR18_HUMAN,tr|H3BM38|H3BM38_HUMAN,tr|H3BU94|H3BU94_HUMAN,tr|H3BPJ0|H3BPJ0_HUMAN" 7 1641.8071 0.74 140221 7258 3 1641.80711 548.2763 Synaptosomal-associated protein 23 OS=Homo sapiens OX=9606 GN=SNAP23 PE=1 SV=1 5.45 1755.9 - 377159 - - - 0.0298 - 1.829 0.306 - 108.4 1 2 0 0 14 0 0 0 6.30E+06 8.47E+06 - - - 3.5561 0.9999 221125_WJC_METTL3_EV_vs_WT_F10.07263.07263.3 1.85E-05 Nov-44 R.LKPPVHYNGPSK.A "sp|P55265|DSRAD_HUMAN,tr|A0A3B3ITG9|A0A3B3ITG9_HUMAN,tr|A0A3B3IRQ9|A0A3B3IRQ9_HUMAN,tr|A0A3B3ISU1|A0A3B3ISU1_HUMAN,tr|A0A7P0Z4K3|A0A7P0Z4K3_HUMAN,tr|A0A7P0TA14|A0A7P0TA14_HUMAN,tr|A0A3B3ISX1|A0A3B3ISX1_HUMAN,tr|A0A7P0Z4F9|A0A7P0Z4F9_HUMAN" 8 1335.7299 0.82 140224 7263 3 1335.731554 446.2506 Double-stranded RNA-specific adenosine deaminase OS=Homo sapiens OX=9606 GN=ADAR PE=1 SV=4 9.7 1756.6 - 259735 - - - 1.2233 - 2 0.486 - 99.5 1 2 0 0.0016 12 0 0 0 4.84E+07 5.91E+07 - - - 5.8793 0.9982 221125_WJC_METTL3_EV_vs_WT_F10.07264.07264.3 0.067 Nov-52 K.LKESNTTKGELQLK.L sp|P12270|TPR_HUMAN 1 1587.8832 4.17 140225 7264 3 1587.886327 530.3017 Nucleoprotein TPR OS=Homo sapiens OX=9606 GN=TPR PE=1 SV=3 8.5 1756.7 - 337409 - - - 1.9781 - 2.279 0.341 - 87.7 1 2 2 0.0031 14 0 0 0 6.93E+06 1.66E+06 - - - 4.5301 1 221125_WJC_METTL3_EV_vs_WT_F10.07268.07268.3 4.23E-07 17/52 R.VRPDYTAQNLDHGK.A "sp|P82930|RT34_HUMAN,tr|C9JJ19|C9JJ19_HUMAN" 2 1612.7958 1.22 140227 7268 3 1612.797468 538.6059 "28S ribosomal protein S34, mitochondrial OS=Homo sapiens OX=9606 GN=MRPS34 PE=1 SV=2" 6.72 1757.2 - 3.01E+06 - - - 1.0541 - 3.486 0.526 - 464.2 1 2 0 0.0017 14 0 0 0 2.56E+08 2.10E+08 - - - 7.7225 0.999 221125_WJC_METTL3_EV_vs_WT_F10.07274.07274.3 1.50E-06 Oct-52 R.TSC[160.03]K[136.11]DDEAVVQAPR[166.11].H "sp|P35658|NU214_HUMAN,tr|A0A0A0MSW3|A0A0A0MSW3_HUMAN,tr|A0A494C1F2|A0A494C1F2_HUMAN" 3 1592.7583 2.08 140231 7274 3 1592.760367 531.9267 Nuclear pore complex protein Nup214 OS=Homo sapiens OX=9606 GN=NUP214 PE=1 SV=2 4.56 1758 - 414057 - - - 1.2726 - 2.151 0.368 - 124.8 1 2 1 0.002 14 0 0 0 1.44E+08 6.92E+07 - - - 4.6778 0.9999 221125_WJC_METTL3_EV_vs_WT_F10.07278.07278.3 3.35E-05 16/52 R.TSC[160.03]KDDEAVVQAPR.H "sp|P35658|NU214_HUMAN,tr|A0A0A0MSW3|A0A0A0MSW3_HUMAN,tr|A0A494C1F2|A0A494C1F2_HUMAN" 3 1574.7359 2.08 140233 7278 3 1574.738308 525.9192 Nuclear pore complex protein Nup214 OS=Homo sapiens OX=9606 GN=NUP214 PE=1 SV=2 4.56 1758.6 - 918712 - - - 1.5482 - 2.785 0.539 - 306.1 1 2 1 0.0024 14 0 0 0 1.43E+08 6.85E+07 - - - 7.2706 0.9994 221125_WJC_METTL3_EV_vs_WT_F10.07281.07281.2 0.00181 26-Jun R.VR[166.11]PDYTAQNLDHGK[136.11].A "sp|P82930|RT34_HUMAN,tr|C9JJ19|C9JJ19_HUMAN" 2 1630.8182 1.14 140236 7281 2 1630.817972 816.4164 "28S ribosomal protein S34, mitochondrial OS=Homo sapiens OX=9606 GN=MRPS34 PE=1 SV=2" 6.72 1758.9 - 85429 - - - -0.1631 - 1.297 0.433 - 81.3 1 2 0 -0.0003 14 0 0 0 4.68E+06 4.09E+06 - - - 2.8916 0.9997 221125_WJC_METTL3_EV_vs_WT_F10.07294.07294.2 0.00137 26-Jun R.VRPDYTAQNLDHGK.A "sp|P82930|RT34_HUMAN,tr|C9JJ19|C9JJ19_HUMAN" 2 1612.7958 1.14 140244 7294 2 1612.796801 807.4052 "28S ribosomal protein S34, mitochondrial OS=Homo sapiens OX=9606 GN=MRPS34 PE=1 SV=2" 6.72 1760.7 - 170591 - - - 0.6405 - 1.443 0.486 - 60 1 2 0 0.001 14 0 0 0 4.68E+06 4.09E+06 - - - 3.5505 0.9994 221125_WJC_METTL3_EV_vs_WT_F10.07303.07303.3 0.000135 Sep-76 K.TGGTVESDGSTESTGR[166.11]LEEK[136.11].G sp|Q8NDV7|TNR6A_HUMAN 1 2056.9516 2.97 140247 7303 3 2056.952137 686.6578 Trinucleotide repeat-containing gene 6A protein OS=Homo sapiens OX=9606 GN=TNRC6A PE=1 SV=2 4.25 1761.9 - 100256 - - - 0.282 - 1.65 0.46 - 86.6 1 2 1 0.0006 20 0 0 0 6.29E+06 2.12E+06 - - - 4.8833 1 221125_WJC_METTL3_EV_vs_WT_F10.07307.07307.3 6.80E-05 17/76 K.TGGTVESDGSTESTGRLEEK.G sp|Q8NDV7|TNR6A_HUMAN 1 2038.9291 2.97 140249 7307 3 2038.928927 680.6503 Trinucleotide repeat-containing gene 6A protein OS=Homo sapiens OX=9606 GN=TNRC6A PE=1 SV=2 4.25 1762.4 - 131003 - - - -0.0785 - 3.52 0.6 - 479.2 1 2 1 -0.0002 20 0 0 0 6.29E+06 2.12E+06 - - - 8.2824 0.9977 221125_WJC_METTL3_EV_vs_WT_F10.07317.07317.2 3.30E-06 26-Jul R.TSC[160.03]KDDEAVVQAPR.H "sp|P35658|NU214_HUMAN,tr|A0A0A0MSW3|A0A0A0MSW3_HUMAN,tr|A0A494C1F2|A0A494C1F2_HUMAN" 3 1574.7359 3.96 140255 7317 2 1574.733207 788.3752 Nuclear pore complex protein Nup214 OS=Homo sapiens OX=9606 GN=NUP214 PE=1 SV=2 4.56 1763.5 - 90791.5 - - - -1.6911 - 1.907 0.576 - 150.8 1 2 1 -0.0027 14 0 0 0 3.49E+06 8.82E+05 - - - 4.9144 0.9998 221125_WJC_METTL3_EV_vs_WT_F10.07328.07328.2 1.74E-06 Jul-34 K.TPGNGDGGSTSEAPQPPR.K "sp|Q15014|MO4L2_HUMAN,tr|Q5JXX2|Q5JXX2_HUMAN,tr|Q5JXX1|Q5JXX1_HUMAN" 3 1723.7762 1.59 140262 7328 2 1723.778431 862.8954 Mortality factor 4-like protein 2 OS=Homo sapiens OX=9606 GN=MORF4L2 PE=1 SV=1 4.37 1765 - 49841.1 - - - 1.3204 - 1.513 0.611 - 82.7 1 2 0 0.0023 18 0 0 0 5.26E+06 3.30E+06 - - - 4.5712 1 221125_WJC_METTL3_EV_vs_WT_F10.07337.07337.3 7.52E-06 15/60 K.HSGPNSADSANDGFVR[166.11].L sp|P52597|HNRPF_HUMAN 1 1639.7214 0.87 140266 7337 3 1639.722742 547.5811 Heterogeneous nuclear ribonucleoprotein F OS=Homo sapiens OX=9606 GN=HNRNPF PE=1 SV=3 5.21 1766.1 - 273080 - - - 0.7995 - 2.769 0.628 - 353.5 1 2 0 0.0013 16 0 0 0 1.62E+07 1.87E+07 - - - 8.1545 0.9601 221125_WJC_METTL3_EV_vs_WT_F10.07341.07341.3 1.15 Aug-36 R.KIVDQIRPDR.Q "sp|Q92841|DDX17_HUMAN,sp|P17844|DDX5_HUMAN,tr|A0A7I2V5F5|A0A7I2V5F5_HUMAN,tr|J3KRZ1|J3KRZ1_HUMAN,tr|J3QSF1|J3QSF1_HUMAN,tr|A0A7I2V507|A0A7I2V507_HUMAN,tr|A0A5H1ZRQ2|A0A5H1ZRQ2_HUMAN,tr|J3KTA4|J3KTA4_HUMAN,tr|A0A0G2JLI4|A0A0G2JLI4_HUMAN,tr|A0A1X7SBZ2|A0A1X7SBZ2_HUMAN,tr|A0A7I2V2S0|A0A7I2V2S0_HUMAN" 11 1238.7095 1.42 140267 7341 3 1238.711716 413.9104 Probable ATP-dependent RNA helicase DDX17 OS=Homo sapiens OX=9606 GN=DDX17 PE=1 SV=2 8.75 1766.6 - 458472 - - - 1.7736 - 1.454 0.148 - 150.6 1 2 0 0.0022 10 0 0 0 5.97E+07 4.21E+07 - - - 1.2826 0.9997 221125_WJC_METTL3_EV_vs_WT_F10.07343.07343.3 0.00285 Dec-44 R.R[166.11]K[136.11]PDTIEVQQMK[136.11].A "sp|P15311|EZRI_HUMAN,sp|P26038|MOES_HUMAN,sp|P35241|RADI_HUMAN,tr|A0A2R8Y5S7|A0A2R8Y5S7_HUMAN,tr|E7EQR4|E7EQR4_HUMAN,tr|A0A2R8Y7M3|A0A2R8Y7M3_HUMAN" 6 1497.8184 0.43 140268 7343 3 1497.821809 500.2801 Ezrin OS=Homo sapiens OX=9606 GN=EZR PE=1 SV=4 8.59 1766.9 - 345867 - - - 2.2973 - 1.969 0.422 - 200 1 2 0 0.0034 12 0 0 0 1.56E+07 3.59E+07 - - - 5.1219 0.9554 221125_WJC_METTL3_EV_vs_WT_F10.07345.07345.3 0.814 Jun-36 R.K[136.11]IVDQIR[166.11]PDR[166.11].Q "sp|Q92841|DDX17_HUMAN,sp|P17844|DDX5_HUMAN,tr|A0A7I2V5F5|A0A7I2V5F5_HUMAN,tr|J3KRZ1|J3KRZ1_HUMAN,tr|J3QSF1|J3QSF1_HUMAN,tr|A0A7I2V507|A0A7I2V507_HUMAN,tr|A0A5H1ZRQ2|A0A5H1ZRQ2_HUMAN,tr|J3KTA4|J3KTA4_HUMAN,tr|A0A0G2JLI4|A0A0G2JLI4_HUMAN,tr|A0A1X7SBZ2|A0A1X7SBZ2_HUMAN,tr|A0A7I2V2S0|A0A7I2V2S0_HUMAN" 11 1266.7403 1.42 140269 7345 3 1266.740939 423.254 Probable ATP-dependent RNA helicase DDX17 OS=Homo sapiens OX=9606 GN=DDX17 PE=1 SV=2 8.75 1767.1 - 452526 - - - 0.5368 - 1.249 0.168 - 46.4 2 2 0 0.0007 10 0 0 0 5.97E+07 4.21E+07 - - - 0.9229 0.9984 221125_WJC_METTL3_EV_vs_WT_F10.07349.07349.4 0.388 16/72 K.DLLHPSPEEEK[136.11]R[166.11]K[136.11].H sp|P42677|RS27_HUMAN 1 1602.8576 0.77 140270 7349 4 1602.861157 401.7217 40S ribosomal protein S27 OS=Homo sapiens OX=9606 GN=RPS27 PE=1 SV=3 5.53 1767.7 - 766789 - - - 2.2254 - 2.521 0.367 - 219 1 2 1 0.0036 13 0 0 0 1.92E+08 2.50E+08 - - - 2.7622 0.9998 221125_WJC_METTL3_EV_vs_WT_F10.07350.07350.3 0.00423 15/48 K.DLLHPSPEEEK[136.11]R[166.11]K[136.11].H sp|P42677|RS27_HUMAN 1 1602.8576 0.47 140271 7350 3 1602.860448 535.2931 40S ribosomal protein S27 OS=Homo sapiens OX=9606 GN=RPS27 PE=1 SV=3 5.53 1767.8 - 428565 - - - 1.7831 - 2.967 0.446 - 408 1 2 1 0.0029 13 0 0 0 8.47E+07 1.78E+08 - - - 6.4603 0.9995 221125_WJC_METTL3_EV_vs_WT_F10.07351.07351.2 0.000171 Apr-34 K.TPGNGDGGSTSEAPQPPR[166.11].K "sp|Q15014|MO4L2_HUMAN,tr|Q5JXX2|Q5JXX2_HUMAN,tr|Q5JXX1|Q5JXX1_HUMAN" 3 1733.7844 1.58 140272 7351 2 1733.785768 867.8995 Mortality factor 4-like protein 2 OS=Homo sapiens OX=9606 GN=MORF4L2 PE=1 SV=1 4.37 1768 - 55633.9 - - - 0.7746 - 1.089 0.547 - 27.5 1 2 0 0.0013 18 0 0 0 5.21E+06 3.30E+06 - - - 3.2903 1 221125_WJC_METTL3_EV_vs_WT_F10.07355.07355.2 6.21E-10 18/38 R.SGGGGGGGGC[160.03]GGGGGVSSLR.L "sp|P13645|K1C10_HUMAN,tr|A0A1B0GVI3|A0A1B0GVI3_HUMAN" 2 1548.6699 999 140274 7355 2 1548.672034 775.3422 "Keratin, type I cytoskeletal 10 OS=Homo sapiens OX=9606 GN=KRT10 PE=1 SV=6" 7.96 1768.5 - 217825 - - - 1.3676 - 3.625 0.749 - 959.9 1 2 0 0.0021 20 0 0 0 5.33E+07 0.00E+00 - - - 7.7387 0.9999 221125_WJC_METTL3_EV_vs_WT_F10.07362.07362.3 3.94E-06 14/52 K.R[166.11]YESHPVC[160.03]ADLQAK[136.11].L "sp|Q9NX63|MIC19_HUMAN,tr|C9JRZ6|C9JRZ6_HUMAN" 2 1690.8216 1.93 140279 7362 3 1690.825535 564.6145 MICOS complex subunit MIC19 OS=Homo sapiens OX=9606 GN=CHCHD3 PE=1 SV=1 6.74 1769.5 - 216644 - - - 2.3219 - 2.262 0.478 - 233.2 1 2 0 0.0039 14 0 0 0 7.55E+07 3.90E+07 - - - 6.0373 1 221125_WJC_METTL3_EV_vs_WT_F10.07366.07366.3 2.21E-09 20/52 K.RYESHPVC[160.03]ADLQAK.L "sp|Q9NX63|MIC19_HUMAN,tr|C9JRZ6|C9JRZ6_HUMAN" 2 1672.7991 1.94 140281 7366 3 1672.801031 558.607 MICOS complex subunit MIC19 OS=Homo sapiens OX=9606 GN=CHCHD3 PE=1 SV=1 6.74 1770 - 603782 - - - 1.131 - 3.433 0.626 - 658.9 1 2 0 0.0019 14 0 0 0 7.56E+07 3.90E+07 - - - 8.7966 1 221125_WJC_METTL3_EV_vs_WT_F10.07367.07367.3 4.87E-10 17/60 K.HSGPNSADSANDGFVR.L sp|P52597|HNRPF_HUMAN 1 1629.7132 0.84 140282 7367 3 1629.718145 544.245 Heterogeneous nuclear ribonucleoprotein F OS=Homo sapiens OX=9606 GN=HNRNPF PE=1 SV=3 5.21 1770.1 - 710167 - - - 3.0582 - 3.332 0.631 - 418.1 1 2 0 0.005 16 0 0 0 1.54E+07 1.84E+07 - - - 8.6619 0.9991 221125_WJC_METTL3_EV_vs_WT_F10.07381.07381.3 9.02E-07 18/48 K.DLLHPSPEEEKRK.H sp|P42677|RS27_HUMAN 1 1576.8209 0.45 140290 7381 3 1576.825078 526.6142 40S ribosomal protein S27 OS=Homo sapiens OX=9606 GN=RPS27 PE=1 SV=3 5.53 1772 - 939561 - - - 2.637 - 2.94 0.376 - 452.1 1 2 1 0.0042 13 0 0 0 7.93E+07 1.76E+08 - - - 5.6548 0.7903 221125_WJC_METTL3_EV_vs_WT_F10.07382.07382.3 0.107 Nov-40 K.EKLDFHEAQQK.K "sp|Q14966|ZN638_HUMAN,tr|C9JWN0|C9JWN0_HUMAN" 2 1371.6783 1.5 140291 7382 3 1371.68299 458.2334 Zinc finger protein 638 OS=Homo sapiens OX=9606 GN=ZNF638 PE=1 SV=2 5.45 1772.1 - 816682 - - - 3.4345 - 1.717 0.151 - 106 1 2 1 0.0047 11 0 0 0 3.53E+07 2.36E+07 - - - 1.7579 0.9999 221125_WJC_METTL3_EV_vs_WT_F10.07385.07385.4 0.000158 14/78 K.RYESHPVC[160.03]ADLQAK.L "sp|Q9NX63|MIC19_HUMAN,tr|C9JRZ6|C9JRZ6_HUMAN" 2 1672.7991 1.87 140292 7385 4 1672.801422 419.2071 MICOS complex subunit MIC19 OS=Homo sapiens OX=9606 GN=CHCHD3 PE=1 SV=1 6.74 1772.5 - 928548 - - - 1.3648 - 2.462 0.437 - 235.1 1 2 0 0.0023 14 0 0 0 2.16E+07 1.15E+07 - - - 3.3569 0.9983 221125_WJC_METTL3_EV_vs_WT_F10.07388.07388.3 0.00012 Sep-44 K.DDVGK[136.11]NVHELEK[136.11].S "sp|P35580|MYH10_HUMAN,sp|P35749|MYH11_HUMAN" 2 1397.7122 1.1 140294 7388 3 1397.71567 466.9113 Myosin-10 OS=Homo sapiens OX=9606 GN=MYH10 PE=1 SV=3 4.75 1772.9 - 266040 - - - 2.5127 - 1.995 0.4 - 68 1 2 1 0.0035 12 0 0 0 1.20E+07 1.08E+07 - - - 4.913 0.9999 221125_WJC_METTL3_EV_vs_WT_F10.07389.07389.3 1.18E-05 15/44 R.RKPDTIEVQQMK.A "sp|P15311|EZRI_HUMAN,sp|P26038|MOES_HUMAN,sp|P35241|RADI_HUMAN,tr|A0A2R8Y5S7|A0A2R8Y5S7_HUMAN,tr|E7EQR4|E7EQR4_HUMAN,tr|A0A2R8Y7M3|A0A2R8Y7M3_HUMAN" 6 1471.7817 0.43 140295 7389 3 1471.78419 491.6012 Ezrin OS=Homo sapiens OX=9606 GN=EZR PE=1 SV=4 8.59 1773 - 460285 - - - 1.6932 - 2.648 0.45 - 321.8 1 2 0 0.0025 12 0 0 0 1.53E+07 3.58E+07 - - - 6.2556 0.9771 221125_WJC_METTL3_EV_vs_WT_F10.07402.07402.4 0.0956 17/72 K.DLLHPSPEEEKRK.H sp|P42677|RS27_HUMAN 1 1576.8209 0.79 140304 7402 4 1576.827476 395.2125 40S ribosomal protein S27 OS=Homo sapiens OX=9606 GN=RPS27 PE=1 SV=3 5.53 1774.6 - 3.36E+06 - - - 4.1577 - 2.427 0.298 - 231.3 1 2 1 0.0066 13 0 0 0 1.98E+08 2.51E+08 - - - 2.1467 0.9991 221125_WJC_METTL3_EV_vs_WT_F10.07414.07414.3 0.0407 13/56 K.TK[136.11]EGVVHGVATVAEK[136.11].T "sp|P37840|SYUA_HUMAN,tr|A0A669KB41|A0A669KB41_HUMAN,tr|D6RA31|D6RA31_HUMAN,tr|A0A669KBH5|A0A669KBH5_HUMAN,tr|E7EPV7|E7EPV7_HUMAN" 5 1539.8592 1.59 140312 7414 3 1539.863691 514.2937 Alpha-synuclein OS=Homo sapiens OX=9606 GN=SNCA PE=1 SV=1 6.42 1776.3 - 1.33E+06 - - - 2.9444 - 2.955 0.406 - 120.7 1 2 1 0.0045 15 0 0 0 8.15E+08 5.12E+08 - - - 5.8925 0.9997 221125_WJC_METTL3_EV_vs_WT_F10.07416.07416.4 1.51E-06 15/84 K.TK[136.11]EGVVHGVATVAEK[136.11].T "sp|P37840|SYUA_HUMAN,tr|A0A669KB41|A0A669KB41_HUMAN,tr|D6RA31|D6RA31_HUMAN,tr|A0A669KBH5|A0A669KBH5_HUMAN,tr|E7EPV7|E7EPV7_HUMAN" 5 1539.8592 1.56 140314 7416 4 1539.862384 385.9721 Alpha-synuclein OS=Homo sapiens OX=9606 GN=SNCA PE=1 SV=1 6.42 1776.5 - 399755 - - - 2.0956 - 2.448 0.485 - 133.8 1 2 1 0.0032 15 0 0 0 1.71E+08 1.09E+08 - - - 3.7669 0.9938 221125_WJC_METTL3_EV_vs_WT_F10.07422.07422.3 0.00101 Dec-80 K.K[136.11]SYLSGGAGAAGGGGADPGNK[136.11].K "sp|P25490|TYY1_HUMAN,tr|H0YJU4|H0YJU4_HUMAN,tr|H0YJV7|H0YJV7_HUMAN" 3 1806.8831 0.9 140318 7422 3 1806.894086 603.3017 Transcriptional repressor protein YY1 OS=Homo sapiens OX=9606 GN=YY1 PE=1 SV=2 8.5 1777.3 - 247878 - - - 6.0579 - 1.997 0.398 - 119.2 1 2 0 0.0109 21 0 0 0 7.00E+07 7.76E+07 - - - 4.6325 0.9973 221125_WJC_METTL3_EV_vs_WT_F10.07423.07423.2 0.000178 28-Jul K.TK[136.11]EGVVHGVATVAEK[136.11].T "sp|P37840|SYUA_HUMAN,tr|A0A669KB41|A0A669KB41_HUMAN,tr|D6RA31|D6RA31_HUMAN,tr|A0A669KBH5|A0A669KBH5_HUMAN,tr|E7EPV7|E7EPV7_HUMAN" 5 1539.8592 1.62 140319 7423 2 1539.860505 770.9369 Alpha-synuclein OS=Homo sapiens OX=9606 GN=SNCA PE=1 SV=1 6.42 1777.5 - 94535.8 - - - 0.8754 - 1.822 0.486 - 113.4 1 2 1 0.0013 15 0 0 0 4.54E+07 2.80E+07 - - - 4.1051 0.9955 221125_WJC_METTL3_EV_vs_WT_F10.07430.07430.3 0.00904 Oct-60 K.ASAETPRPQPVDKLEK.L "sp|Q8ND24|RN214_HUMAN,tr|E9PN76|E9PN76_HUMAN" 2 1764.937 3 140324 7430 3 1764.933988 589.3196 RING finger protein 214 OS=Homo sapiens OX=9606 GN=RNF214 PE=1 SV=2 6.23 1778.4 - 264608 - - - -1.7139 - 1.69 0.334 - 67.2 1 2 1 -0.003 16 0 0 0 2.95E+07 9.84E+06 - - - 3.6093 0.997 221125_WJC_METTL3_EV_vs_WT_F10.07436.07436.3 0.000225 Nov-48 R.DQAEEEPNR[166.11]IPSR[166.11].S sp|Q14676|MDC1_HUMAN 1 1559.7443 1.16 140328 7436 3 1559.743876 520.922 Mediator of DNA damage checkpoint protein 1 OS=Homo sapiens OX=9606 GN=MDC1 PE=1 SV=3 4.41 1779.1 - 517927 - - - -0.2641 - 1.837 0.308 - 206.2 1 2 1 -0.0004 13 0 0 0 1.46E+07 1.26E+07 - - - 3.6226 1 221125_WJC_METTL3_EV_vs_WT_F10.07437.07437.2 6.18E-10 20/28 K.TKEGVVHGVATVAEK.T "sp|P37840|SYUA_HUMAN,tr|A0A669KB41|A0A669KB41_HUMAN,tr|D6RA31|D6RA31_HUMAN,tr|A0A669KBH5|A0A669KBH5_HUMAN,tr|E7EPV7|E7EPV7_HUMAN" 5 1523.8308 1.62 140329 7437 2 1523.831616 762.9227 Alpha-synuclein OS=Homo sapiens OX=9606 GN=SNCA PE=1 SV=1 6.42 1779.3 - 267509 - - - 0.5637 - 4.168 0.652 - 1265.3 1 2 1 0.0009 15 0 0 0 4.54E+07 2.80E+07 - - - 7.3658 0.9996 221125_WJC_METTL3_EV_vs_WT_F10.07444.07444.4 0.00842 13/102 K.K[136.11]GAVAEDGDELR[166.11]TEPEAK[136.11].K "sp|P27695|APEX1_HUMAN,tr|G3V3C7|G3V3C7_HUMAN,tr|G3V5D9|G3V5D9_HUMAN,tr|G3V3M6|G3V3M6_HUMAN,tr|A0A0C4DGK8|A0A0C4DGK8_HUMAN,tr|G3V5Q1|G3V5Q1_HUMAN" 6 1939.9697 0.93 140334 7444 4 1939.972831 485.9997 DNA-(apurinic or apyrimidinic site) endonuclease OS=Homo sapiens OX=9606 GN=APEX1 PE=1 SV=2 4.36 1780.2 - 329920 - - - 1.6036 - 2.442 0.43 - 109.4 1 2 1 0.0031 18 0 0 0 6.78E+06 7.33E+06 - - - 3.2737 0.7842 221125_WJC_METTL3_EV_vs_WT_F10.07448.07448.4 0.00312 Nov-90 K.ASAETPR[166.11]PQPVDK[136.11]LEK[136.11].L "sp|Q8ND24|RN214_HUMAN,tr|E9PN76|E9PN76_HUMAN" 2 1790.9737 2.1 140336 7448 4 1790.974722 448.7507 RING finger protein 214 OS=Homo sapiens OX=9606 GN=RNF214 PE=1 SV=2 6.23 1780.7 - 511309 - - - 0.5801 - 2.111 0.12 - 63.1 1 2 1 0.001 16 0 0 0 5.50E+07 2.61E+07 - - - 0.5334 0.9999 221125_WJC_METTL3_EV_vs_WT_F10.07462.07462.3 5.29E-06 16/48 K.DGVVEITGKHEER.Q "sp|P04792|HSPB1_HUMAN,tr|A0A6Q8PHJ6|A0A6Q8PHJ6_HUMAN,tr|A0A6Q8PFK8|A0A6Q8PFK8_HUMAN" 3 1467.7318 2.31 140346 7462 3 1467.73374 490.2512 Heat shock protein beta-1 OS=Homo sapiens OX=9606 GN=HSPB1 PE=1 SV=2 4.83 1782.6 - 517748 - - - 1.3415 - 3.156 0.481 - 437.8 1 2 1 0.002 13 0 0 0 3.61E+07 1.57E+07 - - - 7.0182 0.9236 221125_WJC_METTL3_EV_vs_WT_F10.07463.07463.3 0.543 May-68 K.LTSDIQGHASHQPAISEK[136.11].T sp|O00311|CDC7_HUMAN 1 1925.9687 0.47 140347 7463 3 1925.967694 642.9968 Cell division cycle 7-related protein kinase OS=Homo sapiens OX=9606 GN=CDC7 PE=1 SV=1 5.99 1782.7 - 101964 - - - -0.4985 - 1.253 0.16 - 27.1 4 2 0 -0.001 18 0 0 0 1.19E+06 2.51E+06 - - - 0.6065 0.9989 221125_WJC_METTL3_EV_vs_WT_F10.07470.07470.3 7.35E-05 Oct-60 K.ASAETPR[166.11]PQPVDK[136.11]LEK[136.11].L "sp|Q8ND24|RN214_HUMAN,tr|E9PN76|E9PN76_HUMAN" 2 1790.9737 2.92 140351 7470 3 1790.974203 597.9985 RING finger protein 214 OS=Homo sapiens OX=9606 GN=RNF214 PE=1 SV=2 6.23 1783.6 - 360792 - - - 0.2903 - 1.824 0.391 - 105.1 1 2 1 0.0005 16 0 0 0 2.88E+07 9.84E+06 - - - 4.4413 1 221125_WJC_METTL3_EV_vs_WT_F10.07471.07471.3 1.06E-10 15/56 R.HAVGNNEFGTVDHER[166.11].L sp|Q9P0J1|PDP1_HUMAN 1 1690.7687 1 140352 7471 3 1690.769487 564.5968 "[Pyruvate dehydrogenase [acetyl-transferring]]-phosphatase 1, mitochondrial OS=Homo sapiens OX=9606 GN=PDP1 PE=1 SV=3" 5.27 1783.7 - 310016 - - - 0.4566 - 2.743 0.64 - 331.4 1 2 0 0.0008 15 0 0 0 5.04E+06 5.05E+06 - - - 8.3081 0.9993 221125_WJC_METTL3_EV_vs_WT_F10.07472.07472.3 0.101 Oct-40 R.KDHNIPGELER.Q sp|P35580|MYH10_HUMAN 1 1306.663 1.05 140353 7472 3 1306.664788 436.5616 Myosin-10 OS=Homo sapiens OX=9606 GN=MYH10 PE=1 SV=3 5.45 1783.8 - 247364 - - - 1.3967 - 2.001 0.293 - 144 1 2 0 0.0018 11 0 0 0 1.18E+07 1.13E+07 - - - 3.7767 0.9999 221125_WJC_METTL3_EV_vs_WT_F10.07489.07489.3 1.89E-06 14/44 R.R[166.11]YDDPEVQK[136.11]DIK[136.11].N "sp|P38646|GRP75_HUMAN,tr|H0Y8K0|H0Y8K0_HUMAN,tr|A0A7I2V2S7|A0A7I2V2S7_HUMAN,tr|A0A7I2V2G2|A0A7I2V2G2_HUMAN,tr|A0A3B3ITI4|A0A3B3ITI4_HUMAN,tr|A0A7I2V3F7|A0A7I2V3F7_HUMAN,tr|A0A7I2YQB2|A0A7I2YQB2_HUMAN,tr|D6RCD7|D6RCD7_HUMAN" 8 1530.7888 0.42 140363 7489 3 1530.789121 511.2702 "Stress-70 protein, mitochondrial OS=Homo sapiens OX=9606 GN=HSPA9 PE=1 SV=2" 4.68 1786 - 649915 - - - 0.1823 - 2.694 0.535 - 251.1 1 2 1 0.0003 12 0 0 0 4.02E+07 9.48E+07 - - - 7.2516 0.9975 221125_WJC_METTL3_EV_vs_WT_F10.07490.07490.3 0.00261 Jun-60 K.EHGVVPQADNATPSER[166.11].F sp|Q99543|DNJC2_HUMAN 1 1715.8102 0.48 140364 7490 3 1715.803116 572.944 DnaJ homolog subfamily C member 2 OS=Homo sapiens OX=9606 GN=DNAJC2 PE=1 SV=4 4.65 1786.2 - 96952.6 - - - -4.1555 - 1.612 0.403 - 40 1 2 0 -0.0071 16 0 0 0 2.17E+06 4.52E+06 - - - 4.2562 0.9967 221125_WJC_METTL3_EV_vs_WT_F10.07491.07491.3 0.00282 Sep-44 K.KKDEELSSALEK.M "sp|Q99816|TS101_HUMAN,tr|F5H442|F5H442_HUMAN" 2 1375.7195 1.61 140365 7491 3 1375.720336 459.5804 Tumor susceptibility gene 101 protein OS=Homo sapiens OX=9606 GN=TSG101 PE=1 SV=2 4.87 1786.3 - 604845 - - - 0.6259 - 1.824 0.299 - 145.8 1 2 1 0.0009 12 0 0 0 2.84E+07 1.76E+07 - - - 3.5393 0.9975 221125_WJC_METTL3_EV_vs_WT_F10.07492.07492.3 0.0083 Dec-44 K.K[136.11]K[136.11]DEELSSALEK[136.11].M "sp|Q99816|TS101_HUMAN,tr|F5H442|F5H442_HUMAN" 2 1399.7621 1.61 140366 7492 3 1399.762361 467.5946 Tumor susceptibility gene 101 protein OS=Homo sapiens OX=9606 GN=TSG101 PE=1 SV=2 4.87 1786.4 - 339428 - - - 0.2043 - 2.239 0.268 - 302.6 1 2 1 0.0003 12 0 0 0 2.84E+07 1.76E+07 - - - 3.7621 0.9999 221125_WJC_METTL3_EV_vs_WT_F10.07498.07498.3 2.15E-06 Dec-52 R.YHGHSMSDPGVSYR[166.11].T "sp|P08559|ODPA_HUMAN,sp|P29803|ODPAT_HUMAN,tr|Q5JPU3|Q5JPU3_HUMAN" 3 1601.692 0.17 140370 7498 3 1601.69813 534.9046 "Pyruvate dehydrogenase E1 component subunit alpha, somatic form, mitochondrial OS=Homo sapiens OX=9606 GN=PDHA1 PE=1 SV=3" 6.92 1787.2 - 273953 - - - 3.7991 - 2.3 0.615 - 174.8 1 2 0 0.0061 14 0 0 0 4.58E+06 2.75E+07 - - - 7.6084 0.9704 221125_WJC_METTL3_EV_vs_WT_F10.07501.07501.3 0.0926 Aug-44 K.HK[136.11]ELQQQLVDAK[136.11].L sp|Q9NUQ3|TXLNG_HUMAN 1 1451.8067 1.31 140371 7501 3 1451.807874 484.9429 Gamma-taxilin OS=Homo sapiens OX=9606 GN=TXLNG PE=1 SV=2 6.75 1787.6 - 261110 - - - 0.7901 - 1.636 0.194 - 87.6 1 2 1 0.0011 12 0 0 0 1.65E+07 1.25E+07 - - - 2.067 0.9995 221125_WJC_METTL3_EV_vs_WT_F10.07504.07504.3 0.000336 Nov-52 K.QEYDESGPSIVHRK.C "sp|Q6S8J3|POTEE_HUMAN,sp|P63261|ACTG_HUMAN,sp|Q9BYX7|ACTBM_HUMAN,sp|P60709|ACTB_HUMAN,sp|A5A3E0|POTEF_HUMAN,sp|P0CG38|POTEI_HUMAN,sp|P0CG39|POTEJ_HUMAN,tr|A0A2R8YFE2|A0A2R8YFE2_HUMAN,tr|A0A804GS07|A0A804GS07_HUMAN,tr|A0A6Q8PFE4|A0A6Q8PFE4_HUMAN,tr|I3L4N8|I3L4N8_HUMAN" 11 1643.7903 1.13 140373 7504 3 1643.788259 548.9374 POTE ankyrin domain family member E OS=Homo sapiens OX=9606 GN=POTEE PE=2 SV=3 5.45 1788 - 205756 - - - -1.2715 - 1.628 0.364 - 120.5 1 2 0 -0.0021 14 0 0 0 1.72E+07 1.52E+07 - - - 3.8928 0.9999 221125_WJC_METTL3_EV_vs_WT_F10.07506.07506.3 0.00272 13/52 K.QEYDESGPSIVHR[166.11]K[136.11].C "sp|Q6S8J3|POTEE_HUMAN,sp|P63261|ACTG_HUMAN,sp|Q9BYX7|ACTBM_HUMAN,sp|P60709|ACTB_HUMAN,sp|A5A3E0|POTEF_HUMAN,sp|P0CG38|POTEI_HUMAN,sp|P0CG39|POTEJ_HUMAN,tr|A0A2R8YFE2|A0A2R8YFE2_HUMAN,tr|A0A804GS07|A0A804GS07_HUMAN,tr|A0A6Q8PFE4|A0A6Q8PFE4_HUMAN,tr|I3L4N8|I3L4N8_HUMAN" 11 1661.8128 1.13 140375 7506 3 1661.809911 554.9449 POTE ankyrin domain family member E OS=Homo sapiens OX=9606 GN=POTEE PE=2 SV=3 5.45 1788.3 - 177877 - - - -1.7499 - 2.287 0.499 - 210.9 1 2 0 -0.0029 14 0 0 0 1.69E+07 1.49E+07 - - - 6.301 0.9998 221125_WJC_METTL3_EV_vs_WT_F10.07508.07508.4 0.00024 19/84 K.TKEGVVHGVATVAEK.T "sp|P37840|SYUA_HUMAN,tr|A0A669KB41|A0A669KB41_HUMAN,tr|D6RA31|D6RA31_HUMAN,tr|A0A669KBH5|A0A669KBH5_HUMAN,tr|E7EPV7|E7EPV7_HUMAN" 5 1523.8308 1.56 140376 7508 4 1523.831669 381.965 Alpha-synuclein OS=Homo sapiens OX=9606 GN=SNCA PE=1 SV=1 6.42 1788.5 - 5.44E+06 - - - 0.5985 - 2.849 0.471 - 289.1 1 2 1 0.0009 15 0 0 0 1.71E+08 1.09E+08 - - - 3.6999 0.9999 221125_WJC_METTL3_EV_vs_WT_F10.07524.07524.2 2.96E-06 22-Sep M.SDTWSSIQAHK[136.11]K[136.11].Q "sp|Q86U44|MTA70_HUMAN,tr|B4E349|B4E349_HUMAN,tr|F5H6D8|F5H6D8_HUMAN,tr|B4DTN4|B4DTN4_HUMAN" 4 1402.7176 0.001 140386 7524 2 1402.717535 702.3661 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 8.33 1790.4 - 202377 - - - -0.0307 - 2.107 0.634 - 255.3 1 2 0 0 12 0 0 0 0.00E+00 2.27E+07 - - - 5.6846 1 221125_WJC_METTL3_EV_vs_WT_F10.07526.07526.3 2.17E-05 17/60 R.TPGR[166.11]PTSSQSYEQNIK[136.11].Q "sp|O60573|IF4E2_HUMAN,tr|B9A044|B9A044_HUMAN,tr|B8ZZ50|B8ZZ50_HUMAN,tr|C9JEL3|C9JEL3_HUMAN" 4 1809.8976 1.83 140388 7526 3 1809.897551 604.3065 Eukaryotic translation initiation factor 4E type 2 OS=Homo sapiens OX=9606 GN=EIF4E2 PE=1 SV=1 8.26 1790.6 - 2.41E+06 - - - -0.0332 - 3.066 0.482 - 394.3 1 2 0 -0.0001 16 0 0 0 1.51E+08 8.25E+07 - - - 6.7885 0.9999 221125_WJC_METTL3_EV_vs_WT_F10.07527.07527.4 0.000767 Nov-78 K.ASAHSIVEC[160.03]DPVRK.E "sp|P52732|KIF11_HUMAN,tr|A0A7I2YQY4|A0A7I2YQY4_HUMAN,tr|A0A7I2V3V3|A0A7I2V3V3_HUMAN" 3 1567.7777 4.07 140389 7527 4 1567.778504 392.9517 Kinesin-like protein KIF11 OS=Homo sapiens OX=9606 GN=KIF11 PE=1 SV=2 6.79 1790.7 - 556837 - - - 0.5281 - 2.026 0.402 - 74.8 1 2 0 0.0008 14 0 0 0 2.64E+08 6.50E+07 - - - 2.9817 1 221125_WJC_METTL3_EV_vs_WT_F10.07528.07528.3 0.000156 16/52 K.ASAHSIVEC[160.03]DPVRK.E "sp|P52732|KIF11_HUMAN,tr|A0A7I2YQY4|A0A7I2YQY4_HUMAN,tr|A0A7I2V3V3|A0A7I2V3V3_HUMAN" 3 1567.7777 4.13 140390 7528 3 1567.77636 523.5998 Kinesin-like protein KIF11 OS=Homo sapiens OX=9606 GN=KIF11 PE=1 SV=2 6.79 1790.8 - 486966 - - - -0.8394 - 2.72 0.468 - 312.1 1 2 0 -0.0013 14 0 0 0 2.60E+08 6.30E+07 - - - 6.4166 0.9999 221125_WJC_METTL3_EV_vs_WT_F10.07529.07529.4 3.73E-05 16/78 K.QEYDESGPSIVHR[166.11]K[136.11].C "sp|Q6S8J3|POTEE_HUMAN,sp|P63261|ACTG_HUMAN,sp|Q9BYX7|ACTBM_HUMAN,sp|P60709|ACTB_HUMAN,sp|A5A3E0|POTEF_HUMAN,sp|P0CG38|POTEI_HUMAN,sp|P0CG39|POTEJ_HUMAN,tr|A0A2R8YFE2|A0A2R8YFE2_HUMAN,tr|A0A804GS07|A0A804GS07_HUMAN,tr|A0A6Q8PFE4|A0A6Q8PFE4_HUMAN,tr|I3L4N8|I3L4N8_HUMAN" 11 1661.8128 1.27 140391 7529 4 1661.810357 416.4605 POTE ankyrin domain family member E OS=Homo sapiens OX=9606 GN=POTEE PE=2 SV=3 5.45 1791 - 328372 - - - -1.4815 - 2.813 0.456 - 272.3 1 2 0 -0.0025 14 0 0 0 1.50E+07 1.18E+07 - - - 3.5708 1 221125_WJC_METTL3_EV_vs_WT_F10.07530.07530.3 1.42E-07 Nov-80 K.TEEAR[166.11]PSPAPGPGTPTGTPTR[166.11].T sp|Q4KMP7|TB10B_HUMAN 1 2096.0401 0.89 140392 7530 3 2096.038199 699.6873 TBC1 domain family member 10B OS=Homo sapiens OX=9606 GN=TBC1D10B PE=1 SV=3 5.81 1791.1 - 123175 - - - -0.9241 - 2.689 0.488 - 79.7 1 2 0 -0.0019 21 0 0 0 1.80E+06 2.02E+06 - - - 6.3517 0.9784 221125_WJC_METTL3_EV_vs_WT_F10.07531.07531.2 0.043 30-Jun R.TPGRPTSSQSYEQNIK.Q "sp|O60573|IF4E2_HUMAN,tr|B9A044|B9A044_HUMAN,tr|B8ZZ50|B8ZZ50_HUMAN,tr|C9JEL3|C9JEL3_HUMAN" 4 1791.8751 4.49 140393 7531 2 1791.872116 896.9448 Eukaryotic translation initiation factor 4E type 2 OS=Homo sapiens OX=9606 GN=EIF4E2 PE=1 SV=1 8.26 1791.2 - 110455 - - - -1.6882 - 1.468 0.084 - 47.7 2 2 0 -0.003 16 0 0 0 2.91E+06 6.47E+05 - - - 0.4698 0.9999 221125_WJC_METTL3_EV_vs_WT_F10.07536.07536.3 4.07E-05 23/56 K.TKEGVVHGVATVAEK.T "sp|P37840|SYUA_HUMAN,tr|A0A669KB41|A0A669KB41_HUMAN,tr|D6RA31|D6RA31_HUMAN,tr|A0A669KBH5|A0A669KBH5_HUMAN,tr|E7EPV7|E7EPV7_HUMAN" 5 1523.8308 1.59 140395 7536 3 1523.831912 508.9509 Alpha-synuclein OS=Homo sapiens OX=9606 GN=SNCA PE=1 SV=1 6.42 1791.9 - 1.59E+07 - - - 0.758 - 3.483 0.463 - 545.5 1 2 1 0.0012 15 0 0 0 8.15E+08 5.12E+08 - - - 6.9579 0.9989 221125_WJC_METTL3_EV_vs_WT_F10.07537.07537.4 0.000704 13/72 R.R[166.11]R[166.11]TEEGPTLSYGR[166.11].D "sp|P43243|MATR3_HUMAN,tr|A8MXP9|A8MXP9_HUMAN,tr|D6R991|D6R991_HUMAN,tr|A0A0R4J2E8|A0A0R4J2E8_HUMAN,tr|D6REM6|D6REM6_HUMAN" 5 1550.7944 1.1 140396 7537 4 1550.795183 388.7059 Matrin-3 OS=Homo sapiens OX=9606 GN=MATR3 PE=1 SV=2 8.74 1791.9 - 1.77E+06 - - - 0.5281 - 2.348 0.358 - 193.8 1 2 1 0.0008 13 0 0 0 7.70E+07 7.02E+07 - - - 2.6583 0.9997 221125_WJC_METTL3_EV_vs_WT_F10.07539.07539.2 0.00517 18-Aug R.QDVDNASLAR.L "sp|P08670|VIME_HUMAN,tr|B0YJC5|B0YJC5_HUMAN,tr|B0YJC4|B0YJC4_HUMAN" 3 1087.5258 2.33 140398 7539 2 1087.525703 544.7702 Vimentin OS=Homo sapiens OX=9606 GN=VIM PE=1 SV=4 4.21 1792.2 - 286110 - - - -0.0901 - 1.471 0.453 - 125.1 1 2 0 -0.0001 10 0 0 0 3.92E+06 1.68E+06 - - - 3.4641 0.9999 221125_WJC_METTL3_EV_vs_WT_F10.07542.07542.3 4.62E-08 21/48 R.R[166.11]R[166.11]TEEGPTLSYGR[166.11].D "sp|P43243|MATR3_HUMAN,tr|A8MXP9|A8MXP9_HUMAN,tr|D6R991|D6R991_HUMAN,tr|A0A0R4J2E8|A0A0R4J2E8_HUMAN,tr|D6REM6|D6REM6_HUMAN" 5 1550.7944 1.18 140399 7542 3 1550.794327 517.9387 Matrin-3 OS=Homo sapiens OX=9606 GN=MATR3 PE=1 SV=2 8.74 1792.6 - 1.24E+07 - - - -0.0239 - 3.533 0.519 - 349.6 1 2 1 0 13 0 0 0 4.45E+08 3.78E+08 - - - 7.7484 0.9935 221125_WJC_METTL3_EV_vs_WT_F10.07543.07543.3 0.299 Jun-48 K.ELNHMLSDTGNRK.A sp|Q96FQ6|S10AG_HUMAN 1 1513.7307 134.95 140400 7543 3 1513.730006 505.5842 Protein S100-A16 OS=Homo sapiens OX=9606 GN=S100A16 PE=1 SV=1 6.85 1792.7 - 240696 - - - -0.475 - 1.491 0.232 - 35.1 2 2 0 -0.0007 13 0 0 0 5.57E+06 4.12E+04 - - - 2.0701 0.9999 221125_WJC_METTL3_EV_vs_WT_F10.07545.07545.3 1.48E-05 18/44 R.HGFEAASIK[136.11]EER[166.11].G "sp|P35580|MYH10_HUMAN,tr|E7ERA5|E7ERA5_HUMAN" 2 1390.696 0.84 140402 7545 3 1390.698585 464.5726 Myosin-10 OS=Homo sapiens OX=9606 GN=MYH10 PE=1 SV=3 5.5 1792.9 - 905048 - - - 1.8602 - 2.938 0.558 - 496.1 1 2 1 0.0026 12 0 0 0 1.82E+07 2.18E+07 - - - 7.7477 0.9362 221125_WJC_METTL3_EV_vs_WT_F10.07548.07548.3 0.00067 Sep-68 K.EATPVVHETEPESGSQPR[166.11].P "sp|Q9Y520|PRC2C_HUMAN,tr|E7EPN9|E7EPN9_HUMAN" 2 1958.9209 1.32 140405 7548 3 1958.926285 653.9809 Protein PRRC2C OS=Homo sapiens OX=9606 GN=PRRC2C PE=1 SV=4 4.48 1793.2 - 115418 - - - 2.7393 - 1.894 0.397 - 94.8 1 1 0 0.0054 18 0 0 0 6.16E+07 4.66E+07 - - - 4.5551 0.9999 221125_WJC_METTL3_EV_vs_WT_F10.07552.07552.3 1.39E-08 21/48 R.RRTEEGPTLSYGR.D "sp|P43243|MATR3_HUMAN,tr|A8MXP9|A8MXP9_HUMAN,tr|D6R991|D6R991_HUMAN,tr|A0A0R4J2E8|A0A0R4J2E8_HUMAN,tr|D6REM6|D6REM6_HUMAN" 5 1520.7696 1.18 140407 7552 3 1520.770646 507.9305 Matrin-3 OS=Homo sapiens OX=9606 GN=MATR3 PE=1 SV=2 8.74 1793.7 - 1.53E+07 - - - 0.7187 - 3.148 0.576 - 350.3 1 2 1 0.0011 13 0 0 0 4.45E+08 3.78E+08 - - - 8.0707 0.9682 221125_WJC_METTL3_EV_vs_WT_F10.07553.07553.4 0.753 13/72 R.RRTEEGPTLSYGR.D "sp|P43243|MATR3_HUMAN,tr|A8MXP9|A8MXP9_HUMAN,tr|D6R991|D6R991_HUMAN,tr|A0A0R4J2E8|A0A0R4J2E8_HUMAN,tr|D6REM6|D6REM6_HUMAN" 5 1520.7696 1.1 140408 7553 4 1520.769438 381.1997 Matrin-3 OS=Homo sapiens OX=9606 GN=MATR3 PE=1 SV=2 8.74 1793.7 - 2.66E+06 - - - -0.0756 - 2.088 0.2 - 172.9 1 2 1 -0.0001 13 0 0 0 7.70E+07 7.02E+07 - - - 1.2397 1 221125_WJC_METTL3_EV_vs_WT_F10.07554.07554.4 0.000131 18/78 K.QEYDESGPSIVHRK.C "sp|Q6S8J3|POTEE_HUMAN,sp|P63261|ACTG_HUMAN,sp|Q9BYX7|ACTBM_HUMAN,sp|P60709|ACTB_HUMAN,sp|A5A3E0|POTEF_HUMAN,sp|P0CG38|POTEI_HUMAN,sp|P0CG39|POTEJ_HUMAN,tr|A0A2R8YFE2|A0A2R8YFE2_HUMAN,tr|A0A804GS07|A0A804GS07_HUMAN,tr|A0A6Q8PFE4|A0A6Q8PFE4_HUMAN,tr|I3L4N8|I3L4N8_HUMAN" 11 1643.7903 1.3 140409 7554 4 1643.791005 411.9549 POTE ankyrin domain family member E OS=Homo sapiens OX=9606 GN=POTEE PE=2 SV=3 5.45 1793.8 - 491673 - - - 0.3991 - 2.083 0.523 - 233.1 1 2 0 0.0007 14 0 0 0 1.53E+07 1.18E+07 - - - 4.0451 0.9875 221125_WJC_METTL3_EV_vs_WT_F10.07556.07556.2 3.12E-05 18-Nov D.TWSSIQAHK[136.11]K[136.11].Q "sp|Q86U44|MTA70_HUMAN,tr|B4E349|B4E349_HUMAN,tr|F5H6D8|F5H6D8_HUMAN,tr|B4DTN4|B4DTN4_HUMAN" 4 1200.6586 0.001 140411 7556 2 1200.657248 601.3366 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 10 1794.1 - 251278 - - - -1.131 - 1.871 0.481 - 414 1 1 0 -0.0014 10 0 0 0 0.00E+00 8.93E+06 - - - 4.3419 1 221125_WJC_METTL3_EV_vs_WT_F10.07560.07560.3 8.40E-07 18/52 K.ASAHSIVEC[160.03]DPVR[166.11]K[136.11].E "sp|P52732|KIF11_HUMAN,tr|A0A7I2YQY4|A0A7I2YQY4_HUMAN,tr|A0A7I2V3V3|A0A7I2V3V3_HUMAN" 3 1585.8001 4.13 140413 7560 3 1585.799909 529.6073 Kinesin-like protein KIF11 OS=Homo sapiens OX=9606 GN=KIF11 PE=1 SV=2 6.79 1794.6 - 615168 - - - -0.1495 - 3.311 0.586 - 426.3 1 2 0 -0.0002 14 0 0 0 2.60E+08 6.29E+07 - - - 8.255 0.9995 221125_WJC_METTL3_EV_vs_WT_F10.07561.07561.4 0.000481 13/102 R.LPAGPANR[166.11]PPEPHTQVQR[166.11].A sp|Q96T58|MINT_HUMAN 1 1984.0506 1.64 140414 7561 4 1984.054841 497.0199 Msx2-interacting protein OS=Homo sapiens OX=9606 GN=SPEN PE=1 SV=1 9.61 1794.8 - 237711 - - - 2.1466 - 2.357 0.354 - 55.1 1 2 0 0.0043 18 0 0 0 8.92E+07 5.42E+07 - - - 2.5997 0.9971 221125_WJC_METTL3_EV_vs_WT_F10.07562.07562.3 4.55E-07 13/68 K.EATPVVHETEPESGSQPR.P "sp|Q9Y520|PRC2C_HUMAN,tr|E7EPN9|E7EPN9_HUMAN" 2 1948.9126 1.32 140415 7562 3 1948.911861 650.6448 Protein PRRC2C OS=Homo sapiens OX=9606 GN=PRRC2C PE=1 SV=4 4.48 1794.9 - 309799 - - - -0.4043 - 2.768 0.496 - 204.7 1 1 0 -0.0008 18 0 0 0 6.17E+07 4.66E+07 - - - 6.6049 0.9896 221125_WJC_METTL3_EV_vs_WT_F10.07563.07563.2 1.88E-06 20-Oct S.DTWSSIQAHK[136.11]K[136.11].Q "sp|Q86U44|MTA70_HUMAN,tr|B4E349|B4E349_HUMAN,tr|F5H6D8|F5H6D8_HUMAN,tr|B4DTN4|B4DTN4_HUMAN" 4 1315.6855 0.001 140416 7563 2 1315.683203 658.8501 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 8.6 1795 - 147924 - - - -1.7831 - 1.985 0.605 - 256.9 1 1 0 -0.0023 11 0 0 0 0.00E+00 2.99E+06 - - - 5.3636 0.9922 221125_WJC_METTL3_EV_vs_WT_F10.07567.07567.3 0.00031 Dec-48 A.SAHSIVEC[160.03]DPVRK.E "sp|P52732|KIF11_HUMAN,tr|A0A7I2YQY4|A0A7I2YQY4_HUMAN,tr|A0A7I2V3V3|A0A7I2V3V3_HUMAN" 3 1496.7406 5.27 140418 7567 3 1496.741497 499.9208 Kinesin-like protein KIF11 OS=Homo sapiens OX=9606 GN=KIF11 PE=1 SV=2 6.47 1795.6 - 289636 - - - 0.6247 - 2.19 0.432 - 153.3 1 1 0 0.0009 13 0 0 0 2.66E+07 5.05E+06 - - - 5.4815 1 221125_WJC_METTL3_EV_vs_WT_F10.07568.07568.3 1.37E-08 Dec-56 R.KPDYEPVENTDEAQK.K "sp|Q9NP61|ARFG3_HUMAN,tr|H0Y6A0|H0Y6A0_HUMAN" 2 1761.8057 0.55 140419 7568 3 1761.808035 588.2759 ADP-ribosylation factor GTPase-activating protein 3 OS=Homo sapiens OX=9606 GN=ARFGAP3 PE=1 SV=1 4.18 1795.7 - 324921 - - - 1.3117 - 2.388 0.627 - 180.8 1 2 0 0.0023 15 0 0 0 1.20E+07 2.20E+07 - - - 7.8011 0.9999 221125_WJC_METTL3_EV_vs_WT_F10.07569.07569.3 5.36E-08 16/52 K.VDGLSDDHK[136.11]IETQR[166.11].D "sp|Q9NQL2|RRAGD_HUMAN,sp|Q9HB90|RRAGC_HUMAN" 2 1629.8077 0.63 140420 7569 3 1629.80555 544.2765 Ras-related GTP-binding protein D OS=Homo sapiens OX=9606 GN=RRAGD PE=1 SV=1 4.66 1795.8 - 282763 - - - -1.3394 - 2.914 0.59 - 244.9 1 2 1 -0.0022 14 0 0 0 2.44E+06 3.88E+06 - - - 7.9596 0.9999 221125_WJC_METTL3_EV_vs_WT_F10.07572.07572.3 3.45E-05 17/44 R.RYDDPEVQKDIK.N "sp|P38646|GRP75_HUMAN,tr|H0Y8K0|H0Y8K0_HUMAN,tr|A0A7I2V2S7|A0A7I2V2S7_HUMAN,tr|A0A7I2V2G2|A0A7I2V2G2_HUMAN,tr|A0A3B3ITI4|A0A3B3ITI4_HUMAN,tr|A0A7I2V3F7|A0A7I2V3F7_HUMAN,tr|A0A7I2YQB2|A0A7I2YQB2_HUMAN,tr|D6RCD7|D6RCD7_HUMAN" 8 1504.7522 0.42 140421 7572 3 1504.752601 502.5913 "Stress-70 protein, mitochondrial OS=Homo sapiens OX=9606 GN=HSPA9 PE=1 SV=2" 4.68 1796.2 - 1.43E+06 - - - 0.2851 - 3.111 0.513 - 386.8 1 2 1 0.0004 12 0 0 0 4.02E+07 9.50E+07 - - - 7.4052 0.9999 221125_WJC_METTL3_EV_vs_WT_F10.07574.07574.4 4.75E-05 15/78 K.ASAHSIVEC[160.03]DPVR[166.11]K[136.11].E "sp|P52732|KIF11_HUMAN,tr|A0A7I2YQY4|A0A7I2YQY4_HUMAN,tr|A0A7I2V3V3|A0A7I2V3V3_HUMAN" 3 1585.8001 4.07 140422 7574 4 1585.80047 397.4573 Kinesin-like protein KIF11 OS=Homo sapiens OX=9606 GN=KIF11 PE=1 SV=2 6.79 1796.4 - 1.08E+06 - - - 0.2043 - 2.338 0.458 - 122.1 1 2 0 0.0003 14 0 0 0 2.64E+08 6.50E+07 - - - 3.5214 0.9997 221125_WJC_METTL3_EV_vs_WT_F10.07579.07579.2 0.00305 16-Sep K.QDSGHLDLR[166.11].N "sp|Q86U44|MTA70_HUMAN,tr|B4E349|B4E349_HUMAN,tr|F5H6D8|F5H6D8_HUMAN,tr|B4DTN4|B4DTN4_HUMAN" 4 1049.5129 0.01 140425 7579 2 1049.512258 525.7637 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 5.21 1797.1 - 4.10E+06 - - - -0.6508 - 1.87 0.395 - 241.3 1 2 0 -0.0007 9 0 0 0 1.02E+06 1.13E+08 - - - 3.7691 0.9985 221125_WJC_METTL3_EV_vs_WT_F10.07582.07582.2 0.00021 26-May K.ASAHSIVEC[160.03]DPVRK.E "sp|P52732|KIF11_HUMAN,tr|A0A7I2YQY4|A0A7I2YQY4_HUMAN,tr|A0A7I2V3V3|A0A7I2V3V3_HUMAN" 3 1567.7777 17.72 140427 7582 2 1567.781786 784.8961 Kinesin-like protein KIF11 OS=Homo sapiens OX=9606 GN=KIF11 PE=1 SV=2 6.79 1797.4 - 124054 - - - 2.6215 - 1.354 0.459 - 67.2 1 2 0 0.0041 14 0 0 0 5.02E+06 2.83E+05 - - - 3.1904 0.9144 221125_WJC_METTL3_EV_vs_WT_F10.07587.07587.2 0.654 12-Sep D.SGHLDLR[166.11].N "sp|Q86U44|MTA70_HUMAN,tr|D6R9M9|D6R9M9_HUMAN,tr|B4E349|B4E349_HUMAN,tr|F5H6D8|F5H6D8_HUMAN,tr|B4DTN4|B4DTN4_HUMAN,tr|D6R9X6|D6R9X6_HUMAN" 6 806.4274 0.06 140429 7587 2 806.427282 404.221 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 6.46 1798.2 - 842464 - - - -0.1724 - 1.416 0.25 - 401.5 1 1 0 -0.0001 7 0 0 0 1.50E+06 2.58E+07 - - - 1.9896 0.9992 221125_WJC_METTL3_EV_vs_WT_F10.07589.07589.4 0.00354 16/102 R.LPAGPANRPPEPHTQVQR.A sp|Q96T58|MINT_HUMAN 1 1964.034 1.64 140430 7589 4 1964.037015 492.0158 Msx2-interacting protein OS=Homo sapiens OX=9606 GN=SPEN PE=1 SV=1 9.61 1798.4 - 409677 - - - 1.5137 - 2.464 0.31 - 65.4 1 2 0 0.003 18 0 0 0 8.92E+07 5.42E+07 - - - 2.2323 0.9958 221125_WJC_METTL3_EV_vs_WT_F10.07590.07590.3 0.00237 Oct-36 R.HRNEVTVELR.K sp|O00505|IMA4_HUMAN 1 1251.6684 1.06 140431 7590 3 1251.669031 418.2301 Importin subunit alpha-4 OS=Homo sapiens OX=9606 GN=KPNA3 PE=1 SV=2 6.76 1798.5 - 274946 - - - 0.5177 - 2.14 0.234 - 248.4 1 2 1 0.0006 10 0 0 0 6.96E+06 6.57E+06 - - - 3.3706 0.9994 221125_WJC_METTL3_EV_vs_WT_F10.07595.07595.4 0.00281 17/90 R.LQAAYAGDKADDIQKR.E "sp|Q01082|SPTB2_HUMAN,tr|A0A087WUZ3|A0A087WUZ3_HUMAN" 2 1761.901 1.51 140433 7595 4 1761.903311 441.4825 "Spectrin beta chain, non-erythrocytic 1 OS=Homo sapiens OX=9606 GN=SPTBN1 PE=1 SV=2" 6.04 1799.2 - 397668 - - - 1.3332 - 2.338 0.396 - 207.4 1 2 1 0.0023 16 0 0 0 9.65E+06 6.41E+06 - - - 2.9713 0.9996 221125_WJC_METTL3_EV_vs_WT_F10.07602.07602.2 0.000163 May-38 K.SDQALNC[160.03]GGTASTGSAGNVK[136.11].L sp|O00287|RFXAP_HUMAN 1 1901.8629 2.8 140437 7602 2 1901.862946 951.9387 Regulatory factor X-associated protein OS=Homo sapiens OX=9606 GN=RFXAP PE=1 SV=1 5.55 1800 - 52410.3 - - - 0.041 - 1.516 0.446 - 41.8 1 2 0 0.0001 20 0 0 0 1.10E+06 3.94E+05 - - - 3.3581 0.9999 221125_WJC_METTL3_EV_vs_WT_F10.07606.07606.3 4.10E-06 15/60 R.LQAAYAGDKADDIQKR.E "sp|Q01082|SPTB2_HUMAN,tr|A0A087WUZ3|A0A087WUZ3_HUMAN" 2 1761.901 1.1 140440 7606 3 1761.901923 588.3076 "Spectrin beta chain, non-erythrocytic 1 OS=Homo sapiens OX=9606 GN=SPTBN1 PE=1 SV=2" 6.04 1800.4 - 261746 - - - 0.5454 - 2.863 0.508 - 308.5 1 2 1 0.001 16 0 0 0 4.50E+06 4.11E+06 - - - 6.9024 0.9999 221125_WJC_METTL3_EV_vs_WT_F10.07613.07613.4 1.91E-06 15/90 R.LQAAYAGDK[136.11]ADDIQK[136.11]R[166.11].E "sp|Q01082|SPTB2_HUMAN,tr|A0A087WUZ3|A0A087WUZ3_HUMAN" 2 1787.9376 1.49 140445 7613 4 1787.941019 447.9917 "Spectrin beta chain, non-erythrocytic 1 OS=Homo sapiens OX=9606 GN=SPTBN1 PE=1 SV=2" 6.04 1801.4 - 357538 - - - 1.8944 - 2.949 0.532 - 150.4 1 2 1 0.0034 16 0 0 0 9.59E+06 6.41E+06 - - - 4.2365 1 221125_WJC_METTL3_EV_vs_WT_F10.07617.07617.3 2.00E-09 14/68 R.DAQDVQASQAEADQQQTR.L "sp|Q9P2E9|RRBP1_HUMAN,tr|A0A087WVV2|A0A087WVV2_HUMAN,tr|F8W7S5|F8W7S5_HUMAN" 3 1987.8831 1.35 140447 7617 3 1987.88479 663.635 Ribosome-binding protein 1 OS=Homo sapiens OX=9606 GN=RRBP1 PE=1 SV=5 3.84 1801.9 - 246752 - - - 0.8305 - 3.096 0.678 - 333.3 1 2 0 0.0017 18 0 0 0 2.08E+07 1.54E+07 - - - 8.9127 0.9999 221125_WJC_METTL3_EV_vs_WT_F10.07618.07618.3 3.35E-08 18/60 R.LQAAYAGDK[136.11]ADDIQK[136.11]R[166.11].E "sp|Q01082|SPTB2_HUMAN,tr|A0A087WUZ3|A0A087WUZ3_HUMAN" 2 1787.9376 1.09 140448 7618 3 1787.941415 596.9865 "Spectrin beta chain, non-erythrocytic 1 OS=Homo sapiens OX=9606 GN=SPTBN1 PE=1 SV=2" 6.04 1802.1 - 182308 - - - 2.1158 - 3.492 0.579 - 499.2 1 2 1 0.0038 16 0 0 0 4.46E+06 4.11E+06 - - - 8.2028 1 221125_WJC_METTL3_EV_vs_WT_F10.07619.07619.3 6.47E-13 20/68 R.DAQDVQASQAEADQQQTR[166.11].L "sp|Q9P2E9|RRBP1_HUMAN,tr|A0A087WVV2|A0A087WVV2_HUMAN,tr|F8W7S5|F8W7S5_HUMAN" 3 1997.8914 1.35 140449 7619 3 1997.896088 666.9711 Ribosome-binding protein 1 OS=Homo sapiens OX=9606 GN=RRBP1 PE=1 SV=5 3.84 1802.2 - 224305 - - - 2.342 - 3.777 0.67 - 706.9 1 2 0 0.0047 18 0 0 0 2.08E+07 1.54E+07 - - - 9.3177 0.9965 221125_WJC_METTL3_EV_vs_WT_F10.07627.07627.3 0.0286 Aug-60 R.EFEEESK[136.11]QPGVSEQQR[166.11].H sp|O94776|MTA2_HUMAN 1 1923.8929 1.13 140455 7627 3 1923.896878 642.3049 Metastasis-associated protein MTA2 OS=Homo sapiens OX=9606 GN=MTA2 PE=1 SV=1 4.33 1803.3 - 158130 - - - 2.0578 - 1.583 0.387 - 77.6 1 2 1 0.004 16 0 0 0 3.18E+07 2.81E+07 - - - 4.0321 0.9985 221125_WJC_METTL3_EV_vs_WT_F10.07632.07632.3 0.0015 Dec-44 K.EKYEAIVEENKK.L "sp|Q99417|MYCBP_HUMAN,tr|A0A087WV05|A0A087WV05_HUMAN" 2 1478.7617 1.66 140458 7632 3 1478.76562 493.9278 c-Myc-binding protein OS=Homo sapiens OX=9606 GN=MYCBP PE=1 SV=3 4.95 1803.9 - 824001 - - - 2.6684 - 2.15 0.403 - 175.4 1 2 1 0.0039 12 0 0 0 6.38E+07 3.84E+07 - - - 5.1537 0.9999 221125_WJC_METTL3_EV_vs_WT_F10.07633.07633.3 3.78E-05 Dec-60 K.ELHNTPYGTASEPSEK.A sp|Q9NXV2|KCTD5_HUMAN 1 1758.8061 6 140459 7633 3 1758.808899 587.276 BTB\POZ domain-containing protein KCTD5 OS=Homo sapiens OX=9606 GN=KCTD5 PE=1 SV=1 4.75 1804.1 - 460037 - - - 1.6153 - 2.052 0.455 - 137.9 1 2 0 0.0028 16 0 0 0 6.95E+07 1.16E+07 - - - 5.4564 0.9996 221125_WJC_METTL3_EV_vs_WT_F10.07636.07636.3 1.91E-05 13/60 R.EFEEESKQPGVSEQQR.H sp|O94776|MTA2_HUMAN 1 1905.8704 1.13 140462 7636 3 1905.873704 636.2974 Metastasis-associated protein MTA2 OS=Homo sapiens OX=9606 GN=MTA2 PE=1 SV=1 4.33 1804.5 - 189685 - - - 1.7079 - 2.338 0.455 - 220 1 2 1 0.0033 16 0 0 0 3.15E+07 2.79E+07 - - - 5.7911 1 221125_WJC_METTL3_EV_vs_WT_F10.07637.07637.2 2.38E-08 16/34 R.DAQDVQASQAEADQQQTR.L "sp|Q9P2E9|RRBP1_HUMAN,tr|A0A087WVV2|A0A087WVV2_HUMAN,tr|F8W7S5|F8W7S5_HUMAN" 3 1987.8831 1.34 140463 7637 2 1987.890233 994.9488 Ribosome-binding protein 1 OS=Homo sapiens OX=9606 GN=RRBP1 PE=1 SV=5 3.84 1804.6 - 115387 - - - 3.5686 - 3.354 0.667 - 906.5 1 2 0 0.0071 18 0 0 0 4.76E+06 3.55E+06 - - - 6.9405 1 221125_WJC_METTL3_EV_vs_WT_F10.07643.07643.2 1.79E-05 13/34 R.DAQDVQASQAEADQQQTR[166.11].L "sp|Q9P2E9|RRBP1_HUMAN,tr|A0A087WVV2|A0A087WVV2_HUMAN,tr|F8W7S5|F8W7S5_HUMAN" 3 1997.8914 1.34 140467 7643 2 1997.898639 999.953 Ribosome-binding protein 1 OS=Homo sapiens OX=9606 GN=RRBP1 PE=1 SV=5 3.84 1805.4 - 108158 - - - 3.6188 - 3.016 0.679 - 537.6 1 2 0 0.0072 18 0 0 0 4.76E+06 3.55E+06 - - - 6.7679 0.9998 221125_WJC_METTL3_EV_vs_WT_F10.07647.07647.3 1.09E-05 13/44 K.EK[136.11]YEAIVEENK[136.11]K[136.11].L "sp|Q99417|MYCBP_HUMAN,tr|A0A087WV05|A0A087WV05_HUMAN" 2 1502.8043 1.76 140469 7647 3 1502.807453 501.942 c-Myc-binding protein OS=Homo sapiens OX=9606 GN=MYCBP PE=1 SV=3 4.95 1806 - 1.21E+06 - - - 2.1154 - 2.605 0.497 - 214.5 1 2 1 0.0032 12 0 0 0 6.24E+07 3.54E+07 - - - 6.734 0.9951 221125_WJC_METTL3_EV_vs_WT_F10.07650.07650.3 0.0234 Jun-84 K.AGAPPPSGSAVSTAPQQK[136.11]PIGK[136.11].L sp|P78362|SRPK2_HUMAN 1 2061.119 1.19 140472 7650 3 2061.121509 688.0469 SRSF protein kinase 2 OS=Homo sapiens OX=9606 GN=SRPK2 PE=1 SV=3 10 1806.3 - 93859.4 - - - 1.2401 - 1.282 0.292 - 29.8 1 2 0 0.0026 22 0 0 0 2.33E+06 1.96E+06 - - - 2.3838 0.9998 221125_WJC_METTL3_EV_vs_WT_F10.07660.07660.3 1.32E-06 13/40 K.DSELDK[136.11]HLESR[166.11].V "sp|O75688|PPM1B_HUMAN,tr|B8ZZF0|B8ZZF0_HUMAN,tr|A0A3B3IS24|A0A3B3IS24_HUMAN,tr|C9JIR6|C9JIR6_HUMAN" 4 1345.6593 3.14 140478 7660 3 1345.6618 449.5604 Protein phosphatase 1B OS=Homo sapiens OX=9606 GN=PPM1B PE=1 SV=1 4.75 1807.5 - 948246 - - - 1.8742 - 2.499 0.51 - 359.7 1 2 1 0.0025 11 0 0 0 1.04E+08 3.31E+07 - - - 6.8272 0.9987 221125_WJC_METTL3_EV_vs_WT_F10.07665.07665.3 0.000593 13/52 R.TSKEPPSSPLQPQK.E "sp|Q92615|LAR4B_HUMAN,tr|A0A087X183|A0A087X183_HUMAN,tr|H0Y4V9|H0Y4V9_HUMAN" 3 1522.7991 1.05 140481 7665 3 1522.799592 508.607 La-related protein 4B OS=Homo sapiens OX=9606 GN=LARP4B PE=1 SV=3 8.26 1808.2 - 454389 - - - 0.3086 - 2.163 0.331 - 197.2 1 2 1 0.0005 14 0 0 0 1.51E+07 1.44E+07 - - - 4.2805 1 221125_WJC_METTL3_EV_vs_WT_F10.07666.07666.3 4.19E-05 13/60 K.ELHNTPYGTASEPSEK[136.11].A sp|Q9NXV2|KCTD5_HUMAN 1 1766.8203 5.84 140482 7666 3 1766.822958 589.9474 BTB\POZ domain-containing protein KCTD5 OS=Homo sapiens OX=9606 GN=KCTD5 PE=1 SV=1 4.75 1808.3 - 330553 - - - 1.5282 - 2.077 0.536 - 213.2 1 2 0 0.0027 16 0 0 0 6.76E+07 1.16E+07 - - - 6.3906 1 221125_WJC_METTL3_EV_vs_WT_F10.07672.07672.3 8.17E-08 14/36 R.K[136.11]QDSGHLDLR[166.11].N "sp|Q86U44|MTA70_HUMAN,tr|B4E349|B4E349_HUMAN,tr|F5H6D8|F5H6D8_HUMAN,tr|B4DTN4|B4DTN4_HUMAN" 4 1185.6221 0.05 140485 7672 3 1185.625025 396.2146 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 6.75 1809.1 - 1.07E+06 - - - 2.4628 - 2.585 0.566 - 272.5 1 2 0 0.0029 10 0 0 0 1.38E+06 2.81E+07 - - - 7.6231 0.9999 221125_WJC_METTL3_EV_vs_WT_F10.07674.07674.3 4.20E-07 Dec-48 R.HLADHGQLSGIQR[166.11].A sp|O60783|RT14_HUMAN 1 1440.7461 1.26 140486 7674 3 1440.748874 481.256 "28S ribosomal protein S14, mitochondrial OS=Homo sapiens OX=9606 GN=MRPS14 PE=1 SV=1" 6.92 1809.3 - 243536 - - - 1.9053 - 2.212 0.493 - 164.5 1 2 0 0.0027 13 0 0 0 1.17E+07 9.27E+06 - - - 6.1882 1 221125_WJC_METTL3_EV_vs_WT_F10.07676.07676.3 0.000265 Dec-60 K.HSGPNSADSANDGFVR[166.11].L sp|P52597|HNRPF_HUMAN 1 1639.7214 0.92 140487 7676 3 1639.719576 547.5811 Heterogeneous nuclear ribonucleoprotein F OS=Homo sapiens OX=9606 GN=HNRNPF PE=1 SV=3 5.21 1809.6 - 216065 - - - -1.1313 - 2.244 0.583 - 192.1 1 2 0 -0.0019 16 0 0 0 5.61E+07 6.13E+07 - - - 7.1132 0.9853 221125_WJC_METTL3_EV_vs_WT_F10.07681.07681.3 0.0156 Aug-40 R.DHIFSQQHISK.V sp|Q15911|ZFHX3_HUMAN 1 1338.668 4.56 140489 7681 3 1338.671624 447.23 Zinc finger homeobox protein 3 OS=Homo sapiens OX=9606 GN=ZFHX3 PE=1 SV=2 6.92 1810.3 - 392683 - - - 2.6713 - 1.475 0.234 - 89.3 1 2 0 0.0036 11 0 0 0 8.46E+06 1.86E+06 - - - 2.252 1 221125_WJC_METTL3_EV_vs_WT_F10.07683.07683.3 3.56E-07 13/60 K.HSGPNSADSANDGFVR.L sp|P52597|HNRPF_HUMAN 1 1629.7132 0.88 140491 7683 3 1629.717585 544.245 Heterogeneous nuclear ribonucleoprotein F OS=Homo sapiens OX=9606 GN=HNRNPF PE=1 SV=3 5.21 1810.6 - 222475 - - - 2.7146 - 2.507 0.59 - 156.4 1 2 0 0.0044 16 0 0 0 5.65E+07 6.45E+07 - - - 7.4749 0.9998 221125_WJC_METTL3_EV_vs_WT_F10.07684.07684.3 0.00801 Aug-52 K.SSC[160.03]SFETC[160.03]PRPTEK.Q "sp|Q6WCQ1|MPRIP_HUMAN,tr|A0A494BZV2|A0A494BZV2_HUMAN,tr|J3KSW8|J3KSW8_HUMAN" 3 1684.7185 0.56 140492 7684 3 1684.720243 562.5801 Myosin phosphatase Rho-interacting protein OS=Homo sapiens OX=9606 GN=MPRIP PE=1 SV=3 5.86 1810.7 - 105626 - - - 1.031 - 1.627 0.418 - 45.9 1 2 0 0.0017 14 0 0 0 4.13E+06 7.39E+06 - - - 4.4933 0.995 221125_WJC_METTL3_EV_vs_WT_F10.07688.07688.3 1.13E-05 13/68 R.LPAGPANRPPEPHTQVQR.A sp|Q96T58|MINT_HUMAN 1 1964.034 1.63 140494 7688 3 1964.043962 655.6853 Msx2-interacting protein OS=Homo sapiens OX=9606 GN=SPEN PE=1 SV=1 9.61 1811.3 - 387494 - - - 5.0508 - 2.707 0.29 - 151.9 1 2 0 0.0099 18 0 0 0 1.13E+07 6.92E+06 - - - 4.2502 0.9996 221125_WJC_METTL3_EV_vs_WT_F10.07690.07690.4 3.23E-05 13/90 R.SFGTEDR[166.11]PTDR[166.11]PAPPR[166.11].E "sp|Q9BX40|LS14B_HUMAN,tr|Q5TBQ1|Q5TBQ1_HUMAN,tr|A0A0C4DFV2|A0A0C4DFV2_HUMAN,tr|Q5TBQ0|Q5TBQ0_HUMAN" 4 1827.9006 1.24 140496 7690 4 1827.90558 457.9824 Protein LSM14 homolog B OS=Homo sapiens OX=9606 GN=LSM14B PE=1 SV=1 5.84 1811.5 - 371848 - - - 2.7135 - 1.858 0.4 - 99.8 1 2 0 0.005 16 0 0 0 3.81E+07 3.06E+07 - - - 2.9245 0.9984 221125_WJC_METTL3_EV_vs_WT_F10.07691.07691.3 0.000346 Nov-64 R.K[136.11]ADGVHTVEPTEAGDYK[136.11].L sp|Q13445|TMED1_HUMAN 1 1831.8923 1.99 140497 7691 3 1831.901814 611.638 Transmembrane emp24 domain-containing protein 1 OS=Homo sapiens OX=9606 GN=TMED1 PE=1 SV=1 4.75 1811.6 - 181823 - - - 5.1892 - 2.107 0.44 - 144.9 1 2 0 0.0095 17 0 0 0 1.26E+07 6.31E+06 - - - 5.3257 0.988 221125_WJC_METTL3_EV_vs_WT_F10.07693.07693.2 0.325 30-Mar K.ELHNTPYGTASEPSEK.A sp|Q9NXV2|KCTD5_HUMAN 1 1758.8061 999 140499 7693 2 1758.806265 880.4103 BTB\POZ domain-containing protein KCTD5 OS=Homo sapiens OX=9606 GN=KCTD5 PE=1 SV=1 4.75 1811.9 - 41689.5 - - - 0.1177 - 0.804 0.27 - 18.6 1 2 0 0.0002 16 0 0 0 9.07E+05 0.00E+00 - - - 0.4988 0.9997 221125_WJC_METTL3_EV_vs_WT_F10.07696.07696.3 0.00303 13/68 R.LPAGPANR[166.11]PPEPHTQVQR[166.11].A sp|Q96T58|MINT_HUMAN 1 1984.0506 1.65 140500 7696 3 1984.056664 662.3575 Msx2-interacting protein OS=Homo sapiens OX=9606 GN=SPEN PE=1 SV=1 9.61 1812.3 - 276700 - - - 3.0654 - 2.42 0.416 - 169.7 1 2 0 0.0061 18 0 0 0 1.13E+07 6.86E+06 - - - 5.377 0.9794 221125_WJC_METTL3_EV_vs_WT_F10.07700.07700.3 0.0203 Sep-60 R.SFGTEDR[166.11]PTDR[166.11]PAPPR[166.11].E "sp|Q9BX40|LS14B_HUMAN,tr|Q5TBQ1|Q5TBQ1_HUMAN,tr|A0A0C4DFV2|A0A0C4DFV2_HUMAN,tr|Q5TBQ0|Q5TBQ0_HUMAN" 4 1827.9006 1.24 140503 7700 3 1827.906423 610.3075 Protein LSM14 homolog B OS=Homo sapiens OX=9606 GN=LSM14B PE=1 SV=1 5.84 1812.8 - 291581 - - - 3.1747 - 1.361 0.263 - 38.6 1 2 0 0.0058 16 0 0 0 1.60E+07 1.29E+07 - - - 2.2614 0.9999 221125_WJC_METTL3_EV_vs_WT_F10.07702.07702.3 3.06E-07 14/60 K.VMQQQQQTTQQQLPQK.V sp|Q15459|SF3A1_HUMAN 1 1940.9738 1 140505 7702 3 1940.979111 647.9985 Splicing factor 3A subunit 1 OS=Homo sapiens OX=9606 GN=SF3A1 PE=1 SV=1 8.72 1813.1 - 253349 - - - 2.7316 - 2.007 0.566 - 225 1 2 0 0.0053 16 0 0 0 4.27E+06 4.27E+06 - - - 6.6364 0.9995 221125_WJC_METTL3_EV_vs_WT_F10.07703.07703.3 0.00593 Aug-36 K.NHEEEMNALR.G "sp|Q04695|K1C17_HUMAN,sp|P02533|K1C14_HUMAN,tr|K7EPJ9|K7EPJ9_HUMAN,tr|K7ESE1|K7ESE1_HUMAN,tr|F5GWP8|F5GWP8_HUMAN" 5 1241.5459 0.63 140506 7703 3 1241.547855 414.8559 "Keratin, type I cytoskeletal 17 OS=Homo sapiens OX=9606 GN=KRT17 PE=1 SV=2" 4.75 1813.2 - 212775 - - - 1.5875 - 1.717 0.36 - 166.7 1 2 0 0.002 10 0 0 0 4.22E+06 6.73E+06 - - - 4.1318 0.9998 221125_WJC_METTL3_EV_vs_WT_F10.07707.07707.3 1.18E-05 14/64 K.ASVHTLSGHTNAVATVR[166.11].C "sp|O43660|PLRG1_HUMAN,tr|H0YA24|H0YA24_HUMAN" 2 1729.9099 0.88 140508 7707 3 1729.915014 577.6439 Pleiotropic regulator 1 OS=Homo sapiens OX=9606 GN=PLRG1 PE=1 SV=1 9.81 1813.8 - 361274 - - - 2.9562 - 2.544 0.468 - 240.2 1 2 0 0.0051 17 0 0 0 7.80E+06 8.85E+06 - - - 6.1152 0.9999 221125_WJC_METTL3_EV_vs_WT_F10.07710.07710.3 2.76E-07 16/64 K.ASVHTLSGHTNAVATVR.C "sp|O43660|PLRG1_HUMAN,tr|H0YA24|H0YA24_HUMAN" 2 1719.9016 0.84 140511 7710 3 1719.906569 574.3078 Pleiotropic regulator 1 OS=Homo sapiens OX=9606 GN=PLRG1 PE=1 SV=1 9.81 1814.2 - 241571 - - - 2.8717 - 2.442 0.506 - 329.3 1 2 0 0.0049 17 0 0 0 7.22E+06 8.56E+06 - - - 6.4356 0.9999 221125_WJC_METTL3_EV_vs_WT_F10.07715.07715.2 0.00485 30-Aug K.HSGPNSADSANDGFVR[166.11].L sp|P52597|HNRPF_HUMAN 1 1639.7214 0.86 140514 7715 2 1639.721479 820.868 Heterogeneous nuclear ribonucleoprotein F OS=Homo sapiens OX=9606 GN=HNRNPF PE=1 SV=3 5.21 1814.7 - 80449.2 - - - 0.0293 - 1.76 0.606 - 131.1 1 2 0 0 16 0 0 0 2.21E+06 2.58E+06 - - - 4.9068 0.9999 221125_WJC_METTL3_EV_vs_WT_F10.07716.07716.3 2.92E-06 Dec-60 R.SFGTEDRPTDRPAPPR.E "sp|Q9BX40|LS14B_HUMAN,tr|Q5TBQ1|Q5TBQ1_HUMAN,tr|A0A0C4DFV2|A0A0C4DFV2_HUMAN,tr|Q5TBQ0|Q5TBQ0_HUMAN" 4 1797.8758 1.24 140515 7716 3 1797.879565 600.2992 Protein LSM14 homolog B OS=Homo sapiens OX=9606 GN=LSM14B PE=1 SV=1 5.84 1814.9 - 526586 - - - 2.0886 - 2.069 0.477 - 65.3 1 2 0 0.0038 16 0 0 0 1.60E+07 1.29E+07 - - - 5.7226 0.9994 221125_WJC_METTL3_EV_vs_WT_F10.07717.07717.3 0.0025 Oct-60 K.VMQQQQQTTQQQLPQK[136.11].V sp|Q15459|SF3A1_HUMAN 1 1948.988 1 140516 7717 3 1948.992077 650.6699 Splicing factor 3A subunit 1 OS=Homo sapiens OX=9606 GN=SF3A1 PE=1 SV=1 8.72 1815 - 308726 - - - 2.0872 - 1.814 0.37 - 88.5 1 2 0 0.0041 16 0 0 0 4.27E+06 4.27E+06 - - - 4.1921 0.9986 221125_WJC_METTL3_EV_vs_WT_F10.07718.07718.3 0.0233 Oct-84 K.AGAPPPSGSAVSTAPQQKPIGK.L sp|P78362|SRPK2_HUMAN 1 2045.0906 1.38 140517 7718 3 2045.095195 682.7041 SRSF protein kinase 2 OS=Homo sapiens OX=9606 GN=SRPK2 PE=1 SV=3 10 1815.1 - 123634 - - - 2.2698 - 1.77 0.341 - 80.8 1 2 0 0.0046 22 0 0 0 7.34E+06 5.30E+06 - - - 3.6942 0.9965 221125_WJC_METTL3_EV_vs_WT_F10.07725.07725.3 0.0119 Aug-52 R.TSK[136.11]EPPSSPLQPQK[136.11].E "sp|Q92615|LAR4B_HUMAN,tr|A0A087X183|A0A087X183_HUMAN,tr|H0Y4V9|H0Y4V9_HUMAN" 3 1538.8275 1.83 140522 7725 3 1538.826736 513.9498 La-related protein 4B OS=Homo sapiens OX=9606 GN=LARP4B PE=1 SV=3 8.26 1816.1 - 351778 - - - -0.5108 - 1.845 0.299 - 65.4 1 2 1 -0.0008 14 0 0 0 2.16E+07 1.18E+07 - - - 3.501 1 221125_WJC_METTL3_EV_vs_WT_F10.07727.07727.3 4.06E-10 16/84 R.GLVHAAGPGQDSGSQAGSPPTR.D sp|Q96ER9|MITOK_HUMAN 1 2045.9879 1.59 140524 7727 3 2045.990081 683.0032 Mitochondrial potassium channel OS=Homo sapiens OX=9606 GN=CCDC51 PE=1 SV=2 6.74 1816.3 - 148865 - - - 1.0763 - 3.216 0.641 - 204.4 1 2 0 0.0022 22 0 0 0 2.08E+07 1.31E+07 - - - 8.4554 0.9993 221125_WJC_METTL3_EV_vs_WT_F10.07729.07729.2 0.000277 Jun-40 K.SVSTPSEAGSQDSGDGAVGSR[166.11].T "sp|Q13409|DC1I2_HUMAN,tr|E7EUM4|E7EUM4_HUMAN,tr|E7ET01|E7ET01_HUMAN,tr|E7ERR6|E7ERR6_HUMAN,tr|E7ETL8|E7ETL8_HUMAN,tr|E7EV09|E7EV09_HUMAN,tr|E9PGG1|E9PGG1_HUMAN,tr|E7ESD3|E7ESD3_HUMAN,tr|E7ERH4|E7ERH4_HUMAN,tr|E7EQU2|E7EQU2_HUMAN,tr|E7EQL5|E7EQL5_HUMAN,tr|E7EMU4|E7EMU4_HUMAN" 12 1959.8645 1.05 140526 7729 2 1959.869632 980.9395 Cytoplasmic dynein 1 intermediate chain 2 OS=Homo sapiens OX=9606 GN=DYNC1I2 PE=1 SV=3 4.03 1816.6 - 75279.2 - - - 2.6053 - 1.52 0.544 - 53.9 1 2 0 0.0051 21 0 0 0 6.37E+06 6.08E+06 - - - 4.0868 0.9935 221125_WJC_METTL3_EV_vs_WT_F10.07732.07732.3 0.00284 Nov-44 K.FSLQDPPNKKPK.V sp|O60701|UGDH_HUMAN 1 1397.7667 2.56 140527 7732 3 1397.769122 466.9295 UDP-glucose 6-dehydrogenase OS=Homo sapiens OX=9606 GN=UGDH PE=1 SV=1 9.7 1817 - 644146 - - - 1.7328 - 1.87 0.282 - 103.8 1 2 1 0.0024 12 0 0 0 2.93E+07 1.14E+07 - - - 3.4184 1 221125_WJC_METTL3_EV_vs_WT_F10.07736.07736.3 4.88E-10 14/84 R.GLVHAAGPGQDSGSQAGSPPTR[166.11].D sp|Q96ER9|MITOK_HUMAN 1 2055.9961 1.59 140531 7736 3 2056.000023 686.3393 Mitochondrial potassium channel OS=Homo sapiens OX=9606 GN=CCDC51 PE=1 SV=2 6.74 1817.5 - 149368 - - - 1.8842 - 3.069 0.626 - 174.3 1 2 0 0.0039 22 0 0 0 2.08E+07 1.31E+07 - - - 8.1767 0.991 221125_WJC_METTL3_EV_vs_WT_F10.07739.07739.4 0.104 Dec-90 R.SFGTEDRPTDRPAPPR.E "sp|Q9BX40|LS14B_HUMAN,tr|Q5TBQ1|Q5TBQ1_HUMAN,tr|A0A0C4DFV2|A0A0C4DFV2_HUMAN,tr|Q5TBQ0|Q5TBQ0_HUMAN" 4 1797.8758 1.23 140533 7739 4 1797.880802 450.4762 Protein LSM14 homolog B OS=Homo sapiens OX=9606 GN=LSM14B PE=1 SV=1 5.84 1817.9 - 2.27E+06 - - - 2.7766 - 1.465 0.253 - 76.4 1 2 0 0.005 16 0 0 0 3.77E+07 3.07E+07 - - - 1.5612 1 221125_WJC_METTL3_EV_vs_WT_F10.07743.07743.3 7.87E-06 17/48 K.C[160.03]TKPDC[160.03]PFTHVSR.R "sp|Q6PJT7|ZC3HE_HUMAN,tr|G3V256|G3V256_HUMAN,tr|H0YJ51|H0YJ51_HUMAN,tr|G3V5I6|G3V5I6_HUMAN,tr|H0YJA2|H0YJA2_HUMAN,tr|G3V411|G3V411_HUMAN" 6 1603.7235 0.73 140536 7743 3 1603.725225 535.5818 Zinc finger CCCH domain-containing protein 14 OS=Homo sapiens OX=9606 GN=ZC3H14 PE=1 SV=1 8.07 1818.4 - 252208 - - - 1.0557 - 2.804 0.564 - 420.1 1 2 0 0.0017 13 0 0 0 1.45E+07 1.98E+07 - - - 7.623 0.9997 221125_WJC_METTL3_EV_vs_WT_F10.07744.07744.2 0.000423 30-Jul K.HSGPNSADSANDGFVR.L sp|P52597|HNRPF_HUMAN 1 1629.7132 0.86 140537 7744 2 1629.713662 815.8639 Heterogeneous nuclear ribonucleoprotein F OS=Homo sapiens OX=9606 GN=HNRNPF PE=1 SV=3 5.21 1818.5 - 111942 - - - 0.3074 - 1.535 0.454 - 108.7 1 2 0 0.0005 16 0 0 0 2.21E+06 2.58E+06 - - - 3.4476 0.9996 221125_WJC_METTL3_EV_vs_WT_F10.07751.07751.2 1.28E-07 Aug-40 K.SVSTPSEAGSQDSGDGAVGSR.T "sp|Q13409|DC1I2_HUMAN,tr|E7EUM4|E7EUM4_HUMAN,tr|E7ET01|E7ET01_HUMAN,tr|E7ERR6|E7ERR6_HUMAN,tr|E7ETL8|E7ETL8_HUMAN,tr|E7EV09|E7EV09_HUMAN,tr|E9PGG1|E9PGG1_HUMAN,tr|E7ESD3|E7ESD3_HUMAN,tr|E7ERH4|E7ERH4_HUMAN,tr|E7EQU2|E7EQU2_HUMAN,tr|E7EQL5|E7EQL5_HUMAN,tr|E7EMU4|E7EMU4_HUMAN" 12 1949.8563 1.05 140542 7751 2 1949.861983 975.9354 Cytoplasmic dynein 1 intermediate chain 2 OS=Homo sapiens OX=9606 GN=DYNC1I2 PE=1 SV=3 4.03 1819.4 - 101726 - - - 2.9371 - 2.018 0.653 - 112.3 1 2 0 0.0057 21 0 0 0 6.37E+06 6.08E+06 - - - 5.5884 0.9998 221125_WJC_METTL3_EV_vs_WT_F10.07754.07754.3 6.66E-08 19/44 R.NKFNQVESDKLR.M sp|Q10471|GALT2_HUMAN 1 1476.7685 1.15 140543 7754 3 1476.772801 493.2634 Polypeptide N-acetylgalactosaminyltransferase 2 OS=Homo sapiens OX=9606 GN=GALNT2 PE=1 SV=1 8.59 1819.9 - 1.20E+06 - - - 2.9185 - 3.392 0.534 - 677 1 2 2 0.0043 12 0 0 0 1.73E+07 1.51E+07 - - - 7.878 1 221125_WJC_METTL3_EV_vs_WT_F10.07756.07756.3 7.17E-08 Oct-80 K.SVSTPSEAGSQDSGDGAVGSR[166.11].T "sp|Q13409|DC1I2_HUMAN,tr|E7EUM4|E7EUM4_HUMAN,tr|E7ET01|E7ET01_HUMAN,tr|E7ERR6|E7ERR6_HUMAN,tr|E7ETL8|E7ETL8_HUMAN,tr|E7EV09|E7EV09_HUMAN,tr|E9PGG1|E9PGG1_HUMAN,tr|E7ESD3|E7ESD3_HUMAN,tr|E7ERH4|E7ERH4_HUMAN,tr|E7EQU2|E7EQU2_HUMAN,tr|E7EQL5|E7EQL5_HUMAN,tr|E7EMU4|E7EMU4_HUMAN" 12 1959.8645 0.99 140545 7756 3 1959.864441 654.2955 Cytoplasmic dynein 1 intermediate chain 2 OS=Homo sapiens OX=9606 GN=DYNC1I2 PE=1 SV=3 4.03 1820.1 - 188448 - - - -0.0434 - 2.463 0.512 - 95 1 2 0 -0.0001 21 0 0 0 5.21E+06 5.25E+06 - - - 6.4093 1 221125_WJC_METTL3_EV_vs_WT_F10.07761.07761.3 0.0287 Dec-32 R.HDWDYC[160.03]EHR.D sp|P17568|NDUB7_HUMAN 1 1316.4993 1.83 140548 7761 3 1316.50097 439.8404 NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 7 OS=Homo sapiens OX=9606 GN=NDUFB7 PE=1 SV=4 5.21 1820.8 - 1.01E+06 - - - 1.2921 - 1.85 0.692 - 175.2 1 2 0 0.0017 9 0 0 0 4.79E+07 2.61E+07 - - - 8.1087 1 221125_WJC_METTL3_EV_vs_WT_F10.07762.07762.3 3.50E-06 13/32 R.HDWDYC[160.03]EHR[166.11].D sp|P17568|NDUB7_HUMAN 1 1326.5075 1.85 140549 7762 3 1326.508051 443.1765 NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 7 OS=Homo sapiens OX=9606 GN=NDUFB7 PE=1 SV=4 5.21 1820.9 - 689070 - - - 0.386 - 2.279 0.702 - 276.8 1 2 0 0.0005 9 0 0 0 4.83E+07 2.61E+07 - - - 8.849 0.9999 221125_WJC_METTL3_EV_vs_WT_F10.07763.07763.3 2.32E-05 17/44 R.NYVPEDEDLK[136.11]K[136.11]R[166.11].R "sp|Q8WUD4|CCD12_HUMAN,tr|C9JUN5|C9JUN5_HUMAN,tr|J3KR35|J3KR35_HUMAN,tr|S4R331|S4R331_HUMAN" 4 1530.7888 1.06 140550 7763 3 1530.790633 511.2702 Coiled-coil domain-containing protein 12 OS=Homo sapiens OX=9606 GN=CCDC12 PE=1 SV=1 4.78 1821 - 384738 - - - 1.17 - 2.682 0.505 - 562.4 1 2 1 0.0018 12 0 0 0 1.61E+07 1.52E+07 - - - 6.9044 0.9999 221125_WJC_METTL3_EV_vs_WT_F10.07767.07767.3 7.16E-05 Oct-64 K.SEVQQPVHPKPLSPDSR.A "sp|Q9UHB6|LIMA1_HUMAN,tr|F8VRN8|F8VRN8_HUMAN,tr|F8VQE1|F8VQE1_HUMAN,tr|F8VS07|F8VS07_HUMAN" 4 1899.9803 1.88 140551 7767 3 1899.983617 634.334 LIM domain and actin-binding protein 1 OS=Homo sapiens OX=9606 GN=LIMA1 PE=1 SV=1 6.47 1821.6 - 92286.5 - - - 1.759 - 2.041 0.51 - 132.4 1 2 0 0.0033 17 0 0 0 2.65E+06 1.41E+06 - - - 6.0274 0.9999 221125_WJC_METTL3_EV_vs_WT_F10.07771.07771.3 2.06E-06 13/44 K.TFSGQTHGFVHR.K sp|Q96DG6|CMBL_HUMAN 1 1372.6636 0.74 140554 7771 3 1372.665352 458.5618 Carboxymethylenebutenolidase homolog OS=Homo sapiens OX=9606 GN=CMBL PE=1 SV=1 9.47 1822.1 - 372842 - - - 1.253 - 1.989 0.485 - 245.1 1 2 0 0.0017 12 0 0 0 7.02E+06 9.50E+06 - - - 5.8528 0.9999 221125_WJC_METTL3_EV_vs_WT_F10.07777.07777.3 9.90E-06 Oct-80 K.SVSTPSEAGSQDSGDGAVGSR.T "sp|Q13409|DC1I2_HUMAN,tr|E7EUM4|E7EUM4_HUMAN,tr|E7ET01|E7ET01_HUMAN,tr|E7ERR6|E7ERR6_HUMAN,tr|E7ETL8|E7ETL8_HUMAN,tr|E7EV09|E7EV09_HUMAN,tr|E9PGG1|E9PGG1_HUMAN,tr|E7ESD3|E7ESD3_HUMAN,tr|E7ERH4|E7ERH4_HUMAN,tr|E7EQU2|E7EQU2_HUMAN,tr|E7EQL5|E7EQL5_HUMAN,tr|E7EMU4|E7EMU4_HUMAN" 12 1949.8563 0.99 140557 7777 3 1949.858426 650.9594 Cytoplasmic dynein 1 intermediate chain 2 OS=Homo sapiens OX=9606 GN=DYNC1I2 PE=1 SV=3 4.03 1822.9 - 160610 - - - 1.1129 - 2.137 0.496 - 87.6 1 2 0 0.0022 21 0 0 0 5.21E+06 5.25E+06 - - - 5.8899 0.9996 221125_WJC_METTL3_EV_vs_WT_F10.07783.07783.3 0.00092 Dec-44 R.TEFAGDKFKEEK.V "sp|O43615|TIM44_HUMAN,tr|M0QXU7|M0QXU7_HUMAN" 2 1427.6933 1.26 140561 7783 3 1427.696227 476.905 Mitochondrial import inner membrane translocase subunit TIM44 OS=Homo sapiens OX=9606 GN=TIMM44 PE=1 SV=2 4.87 1823.7 - 729712 - - - 2.0782 - 2.396 0.463 - 141.8 1 2 2 0.003 12 0 0 0 1.48E+07 1.17E+07 - - - 6.1232 0.9999 221125_WJC_METTL3_EV_vs_WT_F10.07790.07790.3 6.23E-05 16/48 K.AHQDIHTQLQDVK[136.11].Q "sp|O00461|GOLI4_HUMAN,tr|F8W785|F8W785_HUMAN" 2 1539.7885 1.8 140566 7790 3 1539.784587 514.2701 Golgi integral membrane protein 4 OS=Homo sapiens OX=9606 GN=GOLIM4 PE=1 SV=1 5.98 1824.5 - 402449 - - - -2.5445 - 2.53 0.438 - 344.5 1 2 0 -0.0039 13 0 0 0 4.35E+07 2.42E+07 - - - 5.9389 0.9064 221125_WJC_METTL3_EV_vs_WT_F10.07795.07795.3 0.0171 Oct-80 K.LKPGGVGAPSSSSPSPSPSAR.P sp|Q92797|SYMPK_HUMAN 1 1921.9858 1.14 140569 7795 3 1921.985006 641.6692 Symplekin OS=Homo sapiens OX=9606 GN=SYMPK PE=1 SV=2 11 1825.2 - 124853 - - - -0.3892 - 1.732 0.311 - 60.8 1 1 0 -0.0007 21 0 0 0 2.27E+06 1.99E+06 - - - 3.324 1 221125_WJC_METTL3_EV_vs_WT_F10.07796.07796.3 3.60E-06 Nov-64 K.GQDPGAPQLQSESK[136.11]PPK[136.11].K "sp|Q5T3I0|GPTC4_HUMAN,tr|F8W895|F8W895_HUMAN,tr|A0A0A0MRK1|A0A0A0MRK1_HUMAN,tr|E9PAV9|E9PAV9_HUMAN" 4 1778.9134 1.42 140570 7796 3 1778.913452 593.9784 G patch domain-containing protein 4 OS=Homo sapiens OX=9606 GN=GPATCH4 PE=1 SV=2 6.07 1825.3 - 204281 - - - 0.0422 - 2.32 0.498 - 102.1 1 2 0 0.0001 17 0 0 0 1.59E+07 1.12E+07 - - - 6.2182 0.9171 221125_WJC_METTL3_EV_vs_WT_F10.07801.07801.3 0.00156 Jul-64 K.NLDSGHC[160.03]VPEPSSSGQR[166.11].L sp|P48634|PRC2A_HUMAN 1 1835.8096 1.83 140573 7801 3 1835.810461 612.9438 Protein PRRC2A OS=Homo sapiens OX=9606 GN=PRRC2A PE=1 SV=3 5.32 1826 - 140063 - - - 0.4723 - 1.64 0.069 - 55.7 1 2 0 0.0009 17 0 0 0 6.05E+07 3.29E+07 - - - 0.5588 0.9999 221125_WJC_METTL3_EV_vs_WT_F10.07802.07802.3 2.01E-05 Sep-64 K.NLDSGHC[160.03]VPEPSSSGQR.L sp|P48634|PRC2A_HUMAN 1 1825.8013 1.83 140574 7802 3 1825.804019 609.6077 Protein PRRC2A OS=Homo sapiens OX=9606 GN=PRRC2A PE=1 SV=3 5.32 1826.1 - 237883 - - - 1.4761 - 1.768 0.543 - 79 1 2 0 0.0027 17 0 0 0 6.05E+07 3.29E+07 - - - 6.0328 0.9741 221125_WJC_METTL3_EV_vs_WT_F10.07803.07803.3 0.00781 Sep-40 R.R[166.11]EEER[166.11]DPAPWR[166.11].D sp|Q5T481|RBM20_HUMAN 1 1469.7154 0.98 140575 7803 3 1469.717611 490.9124 RNA-binding protein 20 OS=Homo sapiens OX=9606 GN=RBM20 PE=1 SV=3 4.87 1826.2 - 213610 - - - 1.5146 - 1.477 0.245 - 116.2 1 2 1 0.0022 11 0 0 0 7.98E+06 8.15E+06 - - - 2.3789 0.9998 221125_WJC_METTL3_EV_vs_WT_F10.07806.07806.3 3.69E-05 15/44 R.NYVPEDEDLKKR.R "sp|Q8WUD4|CCD12_HUMAN,tr|C9JUN5|C9JUN5_HUMAN,tr|J3KR35|J3KR35_HUMAN,tr|S4R331|S4R331_HUMAN" 4 1504.7522 1.06 140577 7806 3 1504.755357 502.5913 Coiled-coil domain-containing protein 12 OS=Homo sapiens OX=9606 GN=CCDC12 PE=1 SV=1 4.78 1826.6 - 436753 - - - 2.1166 - 2.6 0.507 - 401.5 1 2 1 0.0032 12 0 0 0 1.61E+07 1.52E+07 - - - 6.8402 0.9997 221125_WJC_METTL3_EV_vs_WT_F10.07810.07810.3 0.00184 Oct-48 R.KVVENEIYSESHR.V "sp|Q96I51|RCC1L_HUMAN,tr|A0A087WT38|A0A087WT38_HUMAN" 2 1588.7845 0.96 140579 7810 3 1588.787143 530.6021 RCC1-like G exchanging factor-like protein OS=Homo sapiens OX=9606 GN=RCC1L PE=1 SV=2 5.5 1827.1 - 318493 - - - 1.6415 - 1.859 0.392 - 133.6 1 2 0 0.0026 13 0 0 0 7.62E+06 7.95E+06 - - - 4.5908 0.9975 221125_WJC_METTL3_EV_vs_WT_F10.07811.07811.3 0.00253 Jul-48 K.QNSDHSNGSFNLK[136.11].A "sp|P29084|T2EB_HUMAN,tr|E5RIW4|E5RIW4_HUMAN,tr|E5RH41|E5RH41_HUMAN" 3 1454.663 1.72 140580 7811 3 1454.662236 485.8949 Transcription initiation factor IIE subunit beta OS=Homo sapiens OX=9606 GN=GTF2E2 PE=1 SV=1 6.74 1827.2 - 302292 - - - -0.5046 - 1.371 0.295 - 48.9 1 2 0 -0.0007 13 0 0 0 2.48E+07 1.44E+07 - - - 2.6843 0.9997 221125_WJC_METTL3_EV_vs_WT_F10.07817.07817.3 0.000167 Oct-64 R.VVSSQRPFQESSDNEGR.R "sp|Q9H992|MARH7_HUMAN,tr|F5H6W4|F5H6W4_HUMAN" 2 1920.8926 1.45 140584 7817 3 1920.89802 641.3048 E3 ubiquitin-protein ligase MARCHF7 OS=Homo sapiens OX=9606 GN=MARCHF7 PE=1 SV=1 4.68 1828 - 182997 - - - 2.831 - 1.724 0.486 - 71.8 1 2 0 0.0054 17 0 0 0 3.71E+06 2.56E+06 - - - 5.3329 0.9991 221125_WJC_METTL3_EV_vs_WT_F10.07820.07820.2 4.36E-06 22-Oct R.SQYEQLAEQNRK.D "sp|P13645|K1C10_HUMAN,tr|A0A1B0GVI3|A0A1B0GVI3_HUMAN" 2 1492.727 999 140587 7820 2 1492.733188 747.3708 "Keratin, type I cytoskeletal 10 OS=Homo sapiens OX=9606 GN=KRT10 PE=1 SV=6" 5.86 1828.4 - 83334 - - - 4.132 - 2.331 0.6 - 377.4 1 2 0 0.0062 12 0 0 0 2.20E+07 0.00E+00 - - - 5.6974 0.9998 221125_WJC_METTL3_EV_vs_WT_F10.07831.07831.3 0.00147 Jul-48 R.K[136.11]VVENEIYSESHR[166.11].V "sp|Q96I51|RCC1L_HUMAN,tr|A0A087WT38|A0A087WT38_HUMAN" 2 1606.807 0.98 140592 7831 3 1606.809335 536.6096 RCC1-like G exchanging factor-like protein OS=Homo sapiens OX=9606 GN=RCC1L PE=1 SV=2 5.5 1829.9 - 157361 - - - 1.4501 - 1.529 0.45 - 46.4 1 2 0 0.0023 13 0 0 0 7.71E+06 7.88E+06 - - - 4.7077 0.9999 221125_WJC_METTL3_EV_vs_WT_F10.07837.07837.3 2.26E-06 16/64 K.HVVQSISTQQEKETIAK.C "sp|P24539|AT5F1_HUMAN,tr|Q5QNZ2|Q5QNZ2_HUMAN" 2 1925.0218 1.53 140596 7837 3 1925.02608 642.6812 "ATP synthase F(0) complex subunit B1, mitochondrial OS=Homo sapiens OX=9606 GN=ATP5PB PE=1 SV=2" 6.76 1830.8 - 236712 - - - 2.2208 - 2.952 0.569 - 231 1 2 1 0.0043 17 0 0 0 6.67E+06 4.35E+06 - - - 7.6173 0.9998 221125_WJC_METTL3_EV_vs_WT_F10.07838.07838.4 9.99E-05 Dec-90 K.MMNGGHYTYSENRVEK.D "sp|Q99497|PARK7_HUMAN,tr|K7ELW0|K7ELW0_HUMAN" 2 1914.8353 2.33 140597 7838 4 1914.83798 479.7161 Parkinson disease protein 7 OS=Homo sapiens OX=9606 GN=PARK7 PE=1 SV=2 6.51 1830.9 - 417416 - - - 1.4168 - 2.154 0.5 - 58.5 1 2 1 0.0027 16 0 0 0 3.09E+07 1.33E+07 - - - 3.8475 0.9992 221125_WJC_METTL3_EV_vs_WT_F10.07839.07839.4 9.95E-06 13/72 R.VR[166.11]IEGDNENK[136.11]LPR[166.11].E "sp|P51114|FXR1_HUMAN,tr|E7EU85|E7EU85_HUMAN,tr|E9PFF5|E9PFF5_HUMAN,tr|B4DXZ6|B4DXZ6_HUMAN" 4 1566.8472 0.88 140598 7839 4 1566.85132 392.7191 Fragile X mental retardation syndrome-related protein 1 OS=Homo sapiens OX=9606 GN=FXR1 PE=1 SV=3 6.15 1831 - 316494 - - - 2.6014 - 2.199 0.431 - 207.9 1 2 2 0.0041 13 0 0 0 1.75E+07 1.98E+07 - - - 3.2685 0.9987 221125_WJC_METTL3_EV_vs_WT_F10.07840.07840.3 0.000198 Nov-48 R.VR[166.11]IEGDNENK[136.11]LPR[166.11].E "sp|P51114|FXR1_HUMAN,tr|E7EU85|E7EU85_HUMAN,tr|E9PFF5|E9PFF5_HUMAN,tr|B4DXZ6|B4DXZ6_HUMAN" 4 1566.8472 2.13 140599 7840 3 1566.851532 523.2897 Fragile X mental retardation syndrome-related protein 1 OS=Homo sapiens OX=9606 GN=FXR1 PE=1 SV=3 6.15 1831.1 - 309180 - - - 2.7367 - 1.919 0.452 - 153 1 2 2 0.0043 13 0 0 0 3.73E+07 1.75E+07 - - - 5.3454 0.9911 221125_WJC_METTL3_EV_vs_WT_F10.07846.07846.3 0.00217 Sep-60 K.MMNGGHYTYSENRVEK.D "sp|Q99497|PARK7_HUMAN,tr|K7ELW0|K7ELW0_HUMAN" 2 1914.8353 1.87 140603 7846 3 1914.835276 639.2857 Parkinson disease protein 7 OS=Homo sapiens OX=9606 GN=PARK7 PE=1 SV=2 6.51 1831.9 - 294644 - - - 0.0047 - 1.493 0.294 - 58.7 1 2 1 0 16 0 0 0 9.72E+06 5.19E+06 - - - 2.8462 0.9997 221125_WJC_METTL3_EV_vs_WT_F10.07847.07847.3 3.36E-06 15/64 K.HVVQSISTQQEK[136.11]ETIAK[136.11].C "sp|P24539|AT5F1_HUMAN,tr|Q5QNZ2|Q5QNZ2_HUMAN" 2 1941.0502 1.53 140604 7847 3 1941.053601 648.024 "ATP synthase F(0) complex subunit B1, mitochondrial OS=Homo sapiens OX=9606 GN=ATP5PB PE=1 SV=2" 6.76 1832.1 - 275383 - - - 1.7496 - 2.197 0.494 - 212.1 1 2 1 0.0034 17 0 0 0 6.67E+06 4.35E+06 - - - 6.0351 0.9992 221125_WJC_METTL3_EV_vs_WT_F10.07848.07848.3 0.000673 Jun-60 K.IIHEDGYSEDEC[160.03]KQYK.V sp|P08754|GNAI3_HUMAN 1 2012.8786 0.94 140605 7848 3 2012.874853 671.9668 Guanine nucleotide-binding protein G(i) subunit alpha-3 OS=Homo sapiens OX=9606 GN=GNAI3 PE=1 SV=3 4.5 1832.2 - 87197.8 - - - -1.8476 - 1.379 0.518 - 34.1 1 2 1 -0.0037 16 0 0 0 1.37E+06 1.47E+06 - - - 5.1387 0.9999 221125_WJC_METTL3_EV_vs_WT_F10.07856.07856.3 4.85E-06 Nov-60 K.MMNGGHYTYSENR[166.11]VEK[136.11].D "sp|Q99497|PARK7_HUMAN,tr|K7ELW0|K7ELW0_HUMAN" 2 1932.8577 1.9 140610 7856 3 1932.858775 645.2932 Parkinson disease protein 7 OS=Homo sapiens OX=9606 GN=PARK7 PE=1 SV=2 6.51 1833.2 - 270850 - - - 0.537 - 2.333 0.541 - 122.7 1 2 1 0.001 16 0 0 0 9.85E+06 5.19E+06 - - - 6.745 0.9969 221125_WJC_METTL3_EV_vs_WT_F10.07863.07863.3 0.000893 Sep-72 R.SEEPLKTDSSASNSNSELK.A sp|Q7LBC6|KDM3B_HUMAN 1 2021.9389 0.82 140615 7863 3 2021.941375 674.9869 Lysine-specific demethylase 3B OS=Homo sapiens OX=9606 GN=KDM3B PE=1 SV=2 4.41 1834 - 147415 - - - 1.2127 - 1.729 0.346 - 54.1 1 2 1 0.0025 19 0 0 0 5.55E+06 6.77E+06 - - - 3.7421 0.9999 221125_WJC_METTL3_EV_vs_WT_F10.07864.07864.4 6.63E-08 Dec-90 K.MMNGGHYTYSENR[166.11]VEK[136.11].D "sp|Q99497|PARK7_HUMAN,tr|K7ELW0|K7ELW0_HUMAN" 2 1932.8577 2.62 140616 7864 4 1932.8556 484.2217 Parkinson disease protein 7 OS=Homo sapiens OX=9606 GN=PARK7 PE=1 SV=2 6.51 1834.1 - 1.04E+06 - - - -1.1056 - 2.566 0.511 - 90.2 1 2 1 -0.0021 16 0 0 0 3.57E+07 1.36E+07 - - - 4.0051 0.9999 221125_WJC_METTL3_EV_vs_WT_F10.07868.07868.3 0.00011 Sep-64 K.GQDPGAPQLQSESKPPK.K "sp|Q5T3I0|GPTC4_HUMAN,tr|F8W895|F8W895_HUMAN,tr|A0A0A0MRK1|A0A0A0MRK1_HUMAN,tr|E9PAV9|E9PAV9_HUMAN" 4 1762.885 1.45 140619 7868 3 1762.884614 588.6356 G patch domain-containing protein 4 OS=Homo sapiens OX=9606 GN=GPATCH4 PE=1 SV=2 6.07 1834.6 - 343490 - - - -0.2059 - 1.998 0.47 - 92.6 1 2 0 -0.0004 17 0 0 0 1.60E+07 1.10E+07 - - - 5.5285 0.9943 221125_WJC_METTL3_EV_vs_WT_F10.07870.07870.3 1.10E-05 Nov-44 A.HPTLVTYADHSK[136.11].L "sp|Q86U44|MTA70_HUMAN,tr|F5H6D8|F5H6D8_HUMAN,tr|H0YFV6|H0YFV6_HUMAN,tr|B4DTN4|B4DTN4_HUMAN" 4 1375.6976 0.02 140620 7870 3 1375.696914 459.5731 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 6.92 1834.8 - 309862 - - - -0.4725 - 2.009 0.479 - 176.3 1 1 0 -0.0006 12 0 0 0 1.71E+05 6.95E+06 - - - 5.8139 1 221125_WJC_METTL3_EV_vs_WT_F10.07880.07880.3 6.73E-07 Dec-44 R.DEHQDFMDEQK[136.11]R[166.11].L "sp|Q9Y291|RT33_HUMAN,tr|C9JBY7|C9JBY7_HUMAN" 2 1594.6801 0.98 140628 7880 3 1594.680848 532.5673 "28S ribosomal protein S33, mitochondrial OS=Homo sapiens OX=9606 GN=MRPS33 PE=1 SV=1" 4.43 1836.1 - 404948 - - - 0.4753 - 2.575 0.669 - 239.3 1 2 0 0.0008 12 0 0 0 9.43E+06 9.61E+06 - - - 8.6202 0.9851 221125_WJC_METTL3_EV_vs_WT_F10.07885.07885.4 0.0595 Jul-72 K.QEPERNEC[160.03]FLQHK.D "sp|P02768|ALBU_HUMAN,tr|A0A087WWT3|A0A087WWT3_HUMAN,tr|H7C013|H7C013_HUMAN,tr|A0A0C4DGB6|A0A0C4DGB6_HUMAN" 4 1713.7893 169.06 140632 7885 4 1713.79101 429.4546 Albumin OS=Homo sapiens OX=9606 GN=ALB PE=1 SV=2 5.5 1836.7 - 344665 - - - 0.996 - 1.187 0.283 - 22.8 2 2 1 0.0017 13 0 0 0 5.26E+07 3.11E+05 - - - 1.5229 0.9754 221125_WJC_METTL3_EV_vs_WT_F10.07888.07888.3 0.35 Sep-40 R.NGMVLKPHFHK.D "sp|P26373|RL13_HUMAN,tr|H3BTH3|H3BTH3_HUMAN,tr|J3QSB4|J3QSB4_HUMAN" 3 1306.6968 0.95 140633 7888 3 1306.698512 436.5729 60S ribosomal protein L13 OS=Homo sapiens OX=9606 GN=RPL13 PE=1 SV=4 10 1837.1 - 244013 - - - 1.275 - 1.237 0.203 - 89 1 2 0 0.0017 11 0 0 0 5.26E+06 5.52E+06 - - - 1.407 1 221125_WJC_METTL3_EV_vs_WT_F10.07892.07892.3 8.16E-07 18/52 R.HSPSIHQSVVAVSR[166.11].T sp|P35573|GDE_HUMAN 1 1512.8036 1.2 140636 7892 3 1512.804807 505.2752 Glycogen debranching enzyme OS=Homo sapiens OX=9606 GN=AGL PE=1 SV=3 9.76 1837.6 - 437594 - - - 0.7688 - 2.933 0.493 - 318.2 1 2 0 0.0012 14 0 0 0 1.44E+07 1.20E+07 - - - 6.8957 0.8924 221125_WJC_METTL3_EV_vs_WT_F10.07893.07893.3 2.78 Jul-40 R.NGMVLK[136.11]PHFHK[136.11].D "sp|P26373|RL13_HUMAN,tr|H3BTH3|H3BTH3_HUMAN,tr|J3QSB4|J3QSB4_HUMAN" 3 1322.7252 0.96 140637 7893 3 1322.724228 441.9157 60S ribosomal protein L13 OS=Homo sapiens OX=9606 GN=RPL13 PE=1 SV=4 10 1837.7 - 235659 - - - -0.7696 - 1.024 0.161 - 47 1 2 0 -0.001 11 0 0 0 5.26E+06 5.47E+06 - - - 0.4021 0.9815 221125_WJC_METTL3_EV_vs_WT_F10.07894.07894.3 0.0203 Sep-60 R.DGGGR[166.11]GPDELEGPDSK[136.11].L sp|P48634|PRC2A_HUMAN 1 1602.7241 0.5 140638 7894 3 1602.717926 535.2486 Protein PRRC2A OS=Homo sapiens OX=9606 GN=PRRC2A PE=1 SV=3 4.11 1837.8 - 160167 - - - -3.8291 - 1.782 0.329 - 72.6 1 2 1 -0.0061 16 0 0 0 2.19E+06 4.37E+06 - - - 3.6887 0.9974 221125_WJC_METTL3_EV_vs_WT_F10.07905.07905.3 0.0097 Nov-52 R.TSKEPPSSPLQPQK.E "sp|Q92615|LAR4B_HUMAN,tr|A0A087X183|A0A087X183_HUMAN,tr|H0Y4V9|H0Y4V9_HUMAN" 3 1522.7991 0.73 140644 7905 3 1522.801241 508.607 La-related protein 4B OS=Homo sapiens OX=9606 GN=LARP4B PE=1 SV=3 8.26 1839.3 - 404490 - - - 1.3915 - 1.941 0.328 - 136.7 1 2 1 0.0021 14 0 0 0 1.19E+07 1.63E+07 - - - 3.9588 1 221125_WJC_METTL3_EV_vs_WT_F10.07913.07913.3 7.97E-07 13/36 R.K[136.11]QDSGHLDLR[166.11].N "sp|Q86U44|MTA70_HUMAN,tr|B4E349|B4E349_HUMAN,tr|F5H6D8|F5H6D8_HUMAN,tr|B4DTN4|B4DTN4_HUMAN" 4 1185.6221 0.03 140651 7913 3 1185.623756 396.2146 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 6.75 1840.3 - 835231 - - - 1.3925 - 2.388 0.498 - 211.4 1 2 0 0.0017 10 0 0 0 2.27E+06 7.51E+07 - - - 6.6339 0.9997 221125_WJC_METTL3_EV_vs_WT_F10.07916.07916.3 0.0028 Sep-60 K.LLETTDR[166.11]PDGHQNNLR[166.11].S "sp|Q14974|IMB1_HUMAN,tr|J3KTM9|J3KTM9_HUMAN" 2 1897.9509 1.12 140653 7916 3 1897.949374 633.6576 Importin subunit beta-1 OS=Homo sapiens OX=9606 GN=KPNB1 PE=1 SV=2 5.38 1840.6 - 198880 - - - -0.8183 - 1.999 0.357 - 92.8 1 2 0 -0.0016 16 0 0 0 4.31E+06 3.85E+06 - - - 4.297 0.9996 221125_WJC_METTL3_EV_vs_WT_F10.07917.07917.3 6.02E-05 Sep-72 K.QFSSASSQQGQEEK[136.11]EEDLK[136.11].K "sp|Q9NR50|EI2BG_HUMAN,tr|H0Y580|H0Y580_HUMAN" 2 2169.9997 0.83 140654 7917 3 2169.995921 724.3405 Translation initiation factor eIF-2B subunit gamma OS=Homo sapiens OX=9606 GN=EIF2B3 PE=1 SV=1 4.25 1840.8 - 157191 - - - -1.735 - 2.015 0.492 - 80.5 1 2 1 -0.0038 19 0 0 0 1.49E+06 1.80E+06 - - - 5.7456 0.9997 221125_WJC_METTL3_EV_vs_WT_F10.07920.07920.3 0.0317 Sep-60 K.LLETTDRPDGHQNNLR.S "sp|Q14974|IMB1_HUMAN,tr|J3KTM9|J3KTM9_HUMAN" 2 1877.9344 1.12 140655 7920 3 1877.933355 626.9854 Importin subunit beta-1 OS=Homo sapiens OX=9606 GN=KPNB1 PE=1 SV=2 5.38 1841.2 - 245797 - - - -0.5495 - 1.812 0.384 - 100.1 1 2 0 -0.001 16 0 0 0 4.31E+06 3.85E+06 - - - 4.3462 1 221125_WJC_METTL3_EV_vs_WT_F10.07932.07932.2 1.17E-07 Dec-40 K.TAEPAQPSSASGSGNSDDAIR.S sp|P39880|CUX1_HUMAN 1 2016.8985 1.76 140665 7932 2 2016.906568 1009.4565 Homeobox protein cut-like 1 OS=Homo sapiens OX=9606 GN=CUX1 PE=1 SV=3 4.03 1842.7 - 96420.7 - - - 4.0225 - 2.477 0.618 - 173 1 2 0 0.0081 21 0 0 0 3.95E+07 2.24E+07 - - - 5.833 1 221125_WJC_METTL3_EV_vs_WT_F10.07940.07940.2 1.53E-09 14/40 K.TAEPAQPSSASGSGNSDDAIR[166.11].S sp|P39880|CUX1_HUMAN 1 2026.9067 1.76 140671 7940 2 2026.908133 1014.4606 Homeobox protein cut-like 1 OS=Homo sapiens OX=9606 GN=CUX1 PE=1 SV=3 4.03 1843.7 - 138107 - - - 0.6947 - 2.832 0.684 - 226.2 1 2 0 0.0014 21 0 0 0 3.95E+07 2.24E+07 - - - 6.6519 1 221125_WJC_METTL3_EV_vs_WT_F10.07945.07945.3 2.19E-11 18/80 K.TAEPAQPSSASGSGNSDDAIR.S sp|P39880|CUX1_HUMAN 1 2016.8985 1.46 140674 7945 3 2016.903028 673.3068 Homeobox protein cut-like 1 OS=Homo sapiens OX=9606 GN=CUX1 PE=1 SV=3 4.03 1844.4 - 211783 - - - 2.2673 - 3.575 0.682 - 328.7 1 2 0 0.0046 21 0 0 0 2.78E+07 1.90E+07 - - - 9.1966 1 221125_WJC_METTL3_EV_vs_WT_F10.07946.07946.3 0.000104 14/52 R.HSPSIHQSVVAVSR.T sp|P35573|GDE_HUMAN 1 1502.7954 1.2 140675 7946 3 1502.796811 501.9391 Glycogen debranching enzyme OS=Homo sapiens OX=9606 GN=AGL PE=1 SV=3 9.76 1844.5 - 198844 - - - 0.9562 - 2.645 0.507 - 186.1 1 2 0 0.0014 14 0 0 0 1.44E+07 1.20E+07 - - - 6.7771 1 221125_WJC_METTL3_EV_vs_WT_F10.07947.07947.3 2.42E-09 20/80 K.TAEPAQPSSASGSGNSDDAIR[166.11].S sp|P39880|CUX1_HUMAN 1 2026.9067 1.5 140676 7947 3 2026.906748 676.6429 Homeobox protein cut-like 1 OS=Homo sapiens OX=9606 GN=CUX1 PE=1 SV=3 4.03 1844.7 - 147036 - - - 0.0113 - 3.738 0.643 - 524.3 1 2 0 0 21 0 0 0 2.90E+07 1.93E+07 - - - 8.87 0.9994 221125_WJC_METTL3_EV_vs_WT_F10.07948.07948.2 0.00229 20-Aug R.ADTQTYQPYNK.D sp|P84090|ERH_HUMAN 1 1327.6044 2.94 140677 7948 2 1327.606882 664.8095 Enhancer of rudimentary homolog OS=Homo sapiens OX=9606 GN=ERH PE=1 SV=1 5.88 1844.8 - 139123 - - - 1.8356 - 1.725 0.42 - 221.4 1 2 0 0.0024 11 0 0 0 5.38E+06 1.83E+06 - - - 3.6173 0.9998 221125_WJC_METTL3_EV_vs_WT_F10.07953.07953.3 5.76E-06 14/48 K.YSEKEDKYEEEIK.L "sp|P67936|TPM4_HUMAN,tr|A0A2R8Y5V9|A0A2R8Y5V9_HUMAN,tr|A0A5F9UN72|A0A5F9UN72_HUMAN,tr|K7EPB9|K7EPB9_HUMAN,tr|K7ENT6|K7ENT6_HUMAN,tr|A0A2R8YH90|A0A2R8YH90_HUMAN,tr|A0A2R8YE05|A0A2R8YE05_HUMAN,tr|A0A2R8YHD2|A0A2R8YHD2_HUMAN" 8 1688.7781 2.31 140680 7953 3 1688.780035 563.9333 Tropomyosin alpha-4 chain OS=Homo sapiens OX=9606 GN=TPM4 PE=1 SV=3 4.42 1845.4 - 338431 - - - 1.1387 - 2.44 0.499 - 160.9 1 2 2 0.0019 13 0 0 0 9.50E+06 4.11E+06 - - - 6.5213 0.9991 221125_WJC_METTL3_EV_vs_WT_F10.07957.07957.3 0.00954 16/56 K.LKETGYVVERPSTTK.D "sp|Q9NYF8|BCLF1_HUMAN,tr|E9PKI6|E9PKI6_HUMAN,tr|A0A1W2PQ43|A0A1W2PQ43_HUMAN,tr|E9PK91|E9PK91_HUMAN,tr|E9PK09|E9PK09_HUMAN,tr|E9PQN2|E9PQN2_HUMAN" 6 1706.9203 2.1 140684 7957 3 1706.927008 569.9807 Bcl-2-associated transcription factor 1 OS=Homo sapiens OX=9606 GN=BCLAF1 PE=1 SV=2 8.5 1845.9 - 268574 - - - 3.9299 - 2.722 0.497 - 213.4 1 2 1 0.0067 15 0 0 0 2.93E+09 1.40E+09 - - - 6.6921 0.9882 221125_WJC_METTL3_EV_vs_WT_F10.07962.07962.4 0.00967 Dec-84 K.LKETGYVVERPSTTK.D "sp|Q9NYF8|BCLF1_HUMAN,tr|E9PKI6|E9PKI6_HUMAN,tr|A0A1W2PQ43|A0A1W2PQ43_HUMAN,tr|E9PK91|E9PK91_HUMAN,tr|E9PK09|E9PK09_HUMAN,tr|E9PQN2|E9PQN2_HUMAN" 6 1706.9203 1.99 140687 7962 4 1706.924279 427.7374 Bcl-2-associated transcription factor 1 OS=Homo sapiens OX=9606 GN=BCLAF1 PE=1 SV=2 8.5 1846.6 - 972793 - - - 2.3311 - 2.117 0.274 - 79.8 1 2 1 0.004 15 0 0 0 3.89E+09 1.95E+09 - - - 1.8782 0.9998 221125_WJC_METTL3_EV_vs_WT_F10.07963.07963.3 1.88E-05 13/56 K.LK[136.11]ETGYVVER[166.11]PSTTK[136.11].D "sp|Q9NYF8|BCLF1_HUMAN,tr|E9PKI6|E9PKI6_HUMAN,tr|A0A1W2PQ43|A0A1W2PQ43_HUMAN,tr|E9PK91|E9PK91_HUMAN,tr|E9PK09|E9PK09_HUMAN,tr|E9PQN2|E9PQN2_HUMAN" 6 1732.957 2.1 140688 7963 3 1732.961055 578.6596 Bcl-2-associated transcription factor 1 OS=Homo sapiens OX=9606 GN=BCLAF1 PE=1 SV=2 8.5 1846.7 - 397918 - - - 2.3572 - 2.89 0.549 - 135.9 1 2 1 0.0041 15 0 0 0 2.93E+09 1.40E+09 - - - 7.4289 0.9992 221125_WJC_METTL3_EV_vs_WT_F10.07969.07969.2 0.000318 20-Jul R.ADTQTYQPYNK[136.11].D sp|P84090|ERH_HUMAN 1 1335.6186 2.94 140694 7969 2 1335.620217 668.8166 Enhancer of rudimentary homolog OS=Homo sapiens OX=9606 GN=ERH PE=1 SV=1 5.88 1847.5 - 114373 - - - 1.177 - 1.558 0.369 - 189.2 1 2 0 0.0016 11 0 0 0 5.38E+06 1.83E+06 - - - 2.9655 0.9978 221125_WJC_METTL3_EV_vs_WT_F10.07986.07986.4 0.000199 Oct-84 R.DSYGGPPRREPLPSR.R "sp|Q96E39|RMXL1_HUMAN,sp|P38159|RBMX_HUMAN,tr|H3BUY5|H3BUY5_HUMAN,tr|H3BT71|H3BT71_HUMAN,tr|H0Y6E7|H0Y6E7_HUMAN" 5 1682.8489 1.25 140707 7986 4 1682.849554 421.7195 "RNA binding motif protein, X-linked-like-1 OS=Homo sapiens OX=9606 GN=RBMXL1 PE=1 SV=1" 8.74 1849.6 - 1.03E+06 - - - 0.4088 - 2.165 0.323 - 68.2 1 2 1 0.0007 15 0 0 0 7.43E+07 5.94E+07 - - - 2.3136 0.9973 221125_WJC_METTL3_EV_vs_WT_F10.07987.07987.4 0.0047 Dec-66 R.TNYNDRYDEIRR.H "sp|P62424|RL7A_HUMAN,tr|Q5T8U2|Q5T8U2_HUMAN" 2 1613.7546 0.81 140708 7987 4 1613.755541 404.4459 60S ribosomal protein L7a OS=Homo sapiens OX=9606 GN=RPL7A PE=1 SV=2 5.79 1849.7 - 644244 - - - 0.5633 - 1.773 0.32 - 158.5 1 2 1 0.0009 12 0 0 0 7.65E+06 9.45E+06 - - - 2.2277 0.9996 221125_WJC_METTL3_EV_vs_WT_F10.07988.07988.3 0.00902 14/72 R.IQTVPASHLQQGTASGSSK.A sp|Q6P4R8|NFRKB_HUMAN 1 1895.9701 1.94 140709 7988 3 1895.971085 632.9973 Nuclear factor related to kappa-B-binding protein OS=Homo sapiens OX=9606 GN=NFRKB PE=1 SV=2 8.76 1849.9 - 308634 - - - 0.5174 - 2.44 0.295 - 196.6 1 2 0 0.001 19 0 0 0 3.73E+06 1.92E+06 - - - 4.0202 1 221125_WJC_METTL3_EV_vs_WT_F10.07989.07989.3 6.98E-07 14/52 R.KASAHSIVEC[160.03]DPVR.K "sp|P52732|KIF11_HUMAN,tr|A0A7I2YQY4|A0A7I2YQY4_HUMAN,tr|A0A7I2V3V3|A0A7I2V3V3_HUMAN" 3 1567.7777 6.69 140710 7989 3 1567.778501 523.5998 Kinesin-like protein KIF11 OS=Homo sapiens OX=9606 GN=KIF11 PE=1 SV=2 6.74 1850 - 286198 - - - 0.5262 - 2.779 0.528 - 242.3 1 2 0 0.0008 14 0 0 0 7.16E+07 1.07E+07 - - - 7.1427 0.9987 221125_WJC_METTL3_EV_vs_WT_F10.07997.07997.3 0.000761 Sep-44 R.TNYNDR[166.11]YDEIR[166.11]R[166.11].H "sp|P62424|RL7A_HUMAN,tr|Q5T8U2|Q5T8U2_HUMAN" 2 1643.7794 0.98 140716 7997 3 1643.783644 548.9338 60S ribosomal protein L7a OS=Homo sapiens OX=9606 GN=RPL7A PE=1 SV=2 5.79 1851.1 - 542852 - - - 2.5563 - 1.84 0.443 - 124.7 1 2 1 0.0042 12 0 0 0 5.66E+06 5.78E+06 - - - 5.168 0.9929 221125_WJC_METTL3_EV_vs_WT_F10.08000.08000.2 0.0226 28-Sep K.LKETGYVVERPSTTK.D "sp|Q9NYF8|BCLF1_HUMAN,tr|E9PKI6|E9PKI6_HUMAN,tr|A0A1W2PQ43|A0A1W2PQ43_HUMAN,tr|E9PK91|E9PK91_HUMAN,tr|E9PK09|E9PK09_HUMAN,tr|E9PQN2|E9PQN2_HUMAN" 6 1706.9203 2.27 140719 8000 2 1706.925691 854.4674 Bcl-2-associated transcription factor 1 OS=Homo sapiens OX=9606 GN=BCLAF1 PE=1 SV=2 8.5 1851.5 - 84125.3 - - - 3.1583 - 2.248 0.513 - 147.1 1 2 1 0.0054 15 0 0 0 8.24E+07 3.63E+07 - - - 4.8198 0.9995 221125_WJC_METTL3_EV_vs_WT_F10.08003.08003.3 0.00232 13/52 K.R[166.11]GGNR[166.11]FEPYANPTK[136.11].R "sp|P52272|HNRPM_HUMAN,tr|M0R019|M0R019_HUMAN,tr|M0R0Y6|M0R0Y6_HUMAN,tr|M0R0N3|M0R0N3_HUMAN,tr|A0A087X0X3|A0A087X0X3_HUMAN,tr|M0QYQ7|M0QYQ7_HUMAN,tr|M0R2T0|M0R2T0_HUMAN" 7 1633.8319 1.63 140720 8003 3 1633.8331 545.6179 Heterogeneous nuclear ribonucleoprotein M OS=Homo sapiens OX=9606 GN=HNRNPM PE=1 SV=3 9.99 1851.9 - 539622 - - - 0.7173 - 2.157 0.411 - 182.6 1 2 1 0.0012 14 0 0 0 3.64E+07 2.23E+07 - - - 5.1648 1 221125_WJC_METTL3_EV_vs_WT_F10.08010.08010.4 1.03E-07 17/96 R.SLEEDQEPIVSHQKPGK.G "sp|Q14241|ELOA1_HUMAN,tr|A0A024RAC6|A0A024RAC6_HUMAN" 2 1919.9589 1.33 140725 8010 4 1919.958573 480.997 Elongin-A OS=Homo sapiens OX=9606 GN=ELOA PE=1 SV=2 4.83 1852.8 - 805979 - - - -0.1552 - 2.747 0.498 - 253.3 1 2 0 -0.0003 17 0 0 0 5.36E+07 4.02E+07 - - - 3.9114 1 221125_WJC_METTL3_EV_vs_WT_F10.08012.08012.4 7.40E-10 18/96 R.SLEEDQEPIVSHQK[136.11]PGK[136.11].G "sp|Q14241|ELOA1_HUMAN,tr|A0A024RAC6|A0A024RAC6_HUMAN" 2 1935.9873 1.33 140727 8012 4 1935.991735 485.0041 Elongin-A OS=Homo sapiens OX=9606 GN=ELOA PE=1 SV=2 4.83 1853.1 - 595118 - - - 2.3058 - 3.524 0.638 - 304.4 1 2 0 0.0045 17 0 0 0 5.36E+07 4.02E+07 - - - 5.2152 1 221125_WJC_METTL3_EV_vs_WT_F10.08019.08019.3 6.26E-06 17/64 R.SLEEDQEPIVSHQKPGK.G "sp|Q14241|ELOA1_HUMAN,tr|A0A024RAC6|A0A024RAC6_HUMAN" 2 1919.9589 1.27 140732 8019 3 1919.957743 640.9936 Elongin-A OS=Homo sapiens OX=9606 GN=ELOA PE=1 SV=2 4.83 1853.9 - 549462 - - - -0.5875 - 2.908 0.619 - 186.4 1 2 0 -0.0011 17 0 0 0 2.47E+07 1.95E+07 - - - 8.1377 1 221125_WJC_METTL3_EV_vs_WT_F10.08020.08020.3 1.09E-10 15/64 R.SLEEDQEPIVSHQK[136.11]PGK[136.11].G "sp|Q14241|ELOA1_HUMAN,tr|A0A024RAC6|A0A024RAC6_HUMAN" 2 1935.9873 1.27 140733 8020 3 1935.984377 646.3364 Elongin-A OS=Homo sapiens OX=9606 GN=ELOA PE=1 SV=2 4.83 1854.1 - 531865 - - - -1.4948 - 2.741 0.632 - 164.6 1 2 0 -0.0029 17 0 0 0 2.47E+07 1.95E+07 - - - 8.1327 1 221125_WJC_METTL3_EV_vs_WT_F10.08021.08021.3 1.86E-08 14/64 R.PGTPSDHQSQEASQFER.K "sp|Q6Y7W6|GGYF2_HUMAN,tr|A0A7I2V3H7|A0A7I2V3H7_HUMAN,tr|I1E4Y6|I1E4Y6_HUMAN,tr|A0A7I2V516|A0A7I2V516_HUMAN,tr|A0A7I2V3H0|A0A7I2V3H0_HUMAN,tr|C9JHW1|C9JHW1_HUMAN,tr|A0A7I2V361|A0A7I2V361_HUMAN,tr|E7ESB6|E7ESB6_HUMAN" 8 1899.8347 2.33 140734 8021 3 1899.837012 634.2855 GRB10-interacting GYF protein 2 OS=Homo sapiens OX=9606 GN=GIGYF2 PE=1 SV=1 4.65 1854.2 - 445468 - - - 1.1996 - 3.144 0.646 - 276.5 1 1 0 0.0023 17 0 0 0 6.23E+06 2.68E+06 - - - 8.6355 0.9985 221125_WJC_METTL3_EV_vs_WT_F10.08022.08022.4 0.018 13/72 R.HQEGEIFDTEKEK.Y sp|Q02878|RL6_HUMAN 1 1588.7369 1.8 140735 8022 4 1588.73491 398.1915 60S ribosomal protein L6 OS=Homo sapiens OX=9606 GN=RPL6 PE=1 SV=3 4.57 1854.3 - 542274 - - - -1.2626 - 1.415 0.362 - 56.6 1 2 1 -0.002 13 0 0 0 5.45E+06 3.02E+06 - - - 2.505 0.9999 221125_WJC_METTL3_EV_vs_WT_F10.08023.08023.3 5.70E-05 Oct-56 R.AAHSEGNTTAGLDMR[166.11].E sp|P78371|TCPB_HUMAN 1 1539.6975 0.39 140736 8023 3 1539.698567 514.2398 T-complex protein 1 subunit beta OS=Homo sapiens OX=9606 GN=CCT2 PE=1 SV=4 5.32 1854.4 - 348658 - - - 0.6774 - 1.981 0.476 - 129.6 1 2 0 0.001 15 0 0 0 2.06E+06 5.21E+06 - - - 5.6304 0.9984 221125_WJC_METTL3_EV_vs_WT_F10.08024.08024.2 1.89E-05 28-Oct K.LK[136.11]ETGYVVER[166.11]PSTTK[136.11].D "sp|Q9NYF8|BCLF1_HUMAN,tr|E9PKI6|E9PKI6_HUMAN,tr|A0A1W2PQ43|A0A1W2PQ43_HUMAN,tr|E9PK91|E9PK91_HUMAN,tr|E9PK09|E9PK09_HUMAN,tr|E9PQN2|E9PQN2_HUMAN" 6 1732.957 2.27 140737 8024 2 1732.954549 867.4858 Bcl-2-associated transcription factor 1 OS=Homo sapiens OX=9606 GN=BCLAF1 PE=1 SV=2 8.5 1854.6 - 188963 - - - -1.397 - 2.511 0.532 - 168.6 1 2 1 -0.0024 15 0 0 0 8.24E+07 3.63E+07 - - - 5.2331 1 221125_WJC_METTL3_EV_vs_WT_F10.08030.08030.3 2.52E-10 18/60 R.KINNLNVEENSSGDQR.R sp|Q9Y5V3|MAGD1_HUMAN 1 1815.8711 2.07 140741 8030 3 1815.869542 606.2976 Melanoma-associated antigen D1 OS=Homo sapiens OX=9606 GN=MAGED1 PE=1 SV=3 4.68 1855.3 - 1.35E+06 - - - -0.8679 - 3.424 0.698 - 455.9 1 2 0 -0.0016 16 0 0 0 5.01E+07 2.43E+07 - - - 9.4797 0.9909 221125_WJC_METTL3_EV_vs_WT_F10.08031.08031.3 0.258 Aug-56 K.LKETGYVVER[166.11]PSTTK[136.11].D "sp|Q9NYF8|BCLF1_HUMAN,tr|E9PKI6|E9PKI6_HUMAN,tr|A0A1W2PQ43|A0A1W2PQ43_HUMAN,tr|E9PK91|E9PK91_HUMAN,tr|E9PK09|E9PK09_HUMAN,tr|E9PQN2|E9PQN2_HUMAN" 6 1724.9428 - 140742 8031 3 1724.942069 575.9882 Bcl-2-associated transcription factor 1 OS=Homo sapiens OX=9606 GN=BCLAF1 PE=1 SV=2 8.5 1855.4 - 319107 - - - -0.4064 - 1.749 0.274 - 31 3 2 1 -0.0007 15 0 0 0 - - - - - 2.8326 0.9902 221125_WJC_METTL3_EV_vs_WT_F10.08037.08037.4 2.46E-05 16/72 K.TDRPLPENPYHSR.P sp|P51970|NDUA8_HUMAN 1 1580.7696 1.26 140746 8037 4 1580.768765 396.1997 NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 8 OS=Homo sapiens OX=9606 GN=NDUFA8 PE=1 SV=3 6.42 1856.2 - 1.13E+06 - - - -0.4985 - 2.695 0.427 - 185 1 1 0 -0.0008 13 0 0 0 6.25E+07 4.97E+07 - - - 3.31 1 221125_WJC_METTL3_EV_vs_WT_F10.08038.08038.3 3.12E-09 16/52 R.GNTSGSHIVNHLVR[166.11].A sp|Q92900|RENT1_HUMAN 1 1499.7832 1.05 140747 8038 3 1499.784744 500.935 Regulator of nonsense transcripts 1 OS=Homo sapiens OX=9606 GN=UPF1 PE=1 SV=2 9.76 1856.4 - 619965 - - - 1.0008 - 3.267 0.529 - 428.3 1 2 0 0.0015 14 0 0 0 6.67E+07 6.37E+07 - - - 7.5836 1 221125_WJC_METTL3_EV_vs_WT_F10.08044.08044.3 2.77E-06 15/52 R.GNTSGSHIVNHLVR.A sp|Q92900|RENT1_HUMAN 1 1489.775 0.07 140751 8044 3 1489.77204 497.5989 Regulator of nonsense transcripts 1 OS=Homo sapiens OX=9606 GN=UPF1 PE=1 SV=2 9.76 1857.1 - 857716 - - - -1.9688 - 2.642 0.514 - 366.2 1 2 0 -0.0029 14 0 0 0 8.78E+07 1.28E+09 - - - 6.8517 0.9999 221125_WJC_METTL3_EV_vs_WT_F10.08046.08046.3 7.03E-08 14/44 K.QR[166.11]YPDGIISK[136.11]PK[136.11].N sp|Q86U44|MTA70_HUMAN 1 1426.8143 0 140753 8046 3 1426.811936 476.612 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 9.7 1857.3 - 2.97E+06 - - - -1.6351 - 2.359 0.604 - 325.5 1 2 1 -0.0023 12 0 0 0 1.08E+06 2.85E+08 - - - 7.6523 0.9816 221125_WJC_METTL3_EV_vs_WT_F10.08053.08053.2 0.00027 13/16 Y.VVER[166.11]PSTTK[136.11].D "sp|Q9NYF8|BCLF1_HUMAN,tr|E9PKI6|E9PKI6_HUMAN,tr|A0A1W2PQ43|A0A1W2PQ43_HUMAN,tr|E9PK91|E9PK91_HUMAN,tr|E9PK09|E9PK09_HUMAN,tr|E9PQN2|E9PQN2_HUMAN" 6 1033.5887 1.67 140757 8053 2 1033.587735 517.8016 Bcl-2-associated transcription factor 1 OS=Homo sapiens OX=9606 GN=BCLAF1 PE=1 SV=2 8.72 1858.2 - 1.19E+06 - - - -0.9133 - 2.311 0.303 - 559.2 1 1 0 -0.0009 9 0 0 0 1.38E+08 8.28E+07 - - - 3.7021 1 221125_WJC_METTL3_EV_vs_WT_F10.08054.08054.4 3.25E-07 15/78 R.KASAHSIVEC[160.03]DPVR.K "sp|P52732|KIF11_HUMAN,tr|A0A7I2YQY4|A0A7I2YQY4_HUMAN,tr|A0A7I2V3V3|A0A7I2V3V3_HUMAN" 3 1567.7777 5.77 140758 8054 4 1567.775735 392.9517 Kinesin-like protein KIF11 OS=Homo sapiens OX=9606 GN=KIF11 PE=1 SV=2 6.74 1858.4 - 321041 - - - -1.2381 - 3.012 0.511 - 174.2 1 2 0 -0.0019 14 0 0 0 1.74E+07 3.02E+06 - - - 4.0745 0.9981 221125_WJC_METTL3_EV_vs_WT_F10.08055.08055.3 1.51E-09 19/52 L.KETGYVVERPSTTK.D "sp|Q9NYF8|BCLF1_HUMAN,tr|E9PKI6|E9PKI6_HUMAN,tr|A0A1W2PQ43|A0A1W2PQ43_HUMAN,tr|E9PK91|E9PK91_HUMAN,tr|E9PK09|E9PK09_HUMAN,tr|E9PQN2|E9PQN2_HUMAN" 6 1593.8362 2.65 140759 8055 3 1593.832895 532.286 Bcl-2-associated transcription factor 1 OS=Homo sapiens OX=9606 GN=BCLAF1 PE=1 SV=2 8.5 1858.5 - 586267 - - - -2.0962 - 3.464 0.59 - 404.4 1 1 0 -0.0033 14 0 0 0 4.68E+07 1.77E+07 - - - 8.4188 1 221125_WJC_METTL3_EV_vs_WT_F10.08059.08059.3 2.00E-10 14/60 R.K[136.11]INNLNVEENSSGDQR[166.11].R sp|Q9Y5V3|MAGD1_HUMAN 1 1833.8936 2.08 140761 8059 3 1833.891307 612.3051 Melanoma-associated antigen D1 OS=Homo sapiens OX=9606 GN=MAGED1 PE=1 SV=3 4.68 1859 - 981633 - - - -1.2438 - 3.078 0.651 - 245.4 1 2 0 -0.0023 16 0 0 0 5.06E+07 2.43E+07 - - - 8.6821 0.8907 221125_WJC_METTL3_EV_vs_WT_F10.08062.08062.4 0.0586 Sep-66 K.NFREEPEHDFSK.L "sp|O75410|TACC1_HUMAN,tr|E5RFM9|E5RFM9_HUMAN,tr|R4GMT7|R4GMT7_HUMAN" 3 1533.6848 1.05 140763 8062 4 1533.681257 384.4285 Transforming acidic coiled-coil-containing protein 1 OS=Homo sapiens OX=9606 GN=TACC1 PE=1 SV=2 4.83 1859.4 - 490817 - - - -2.3238 - 1.639 0.182 - 66 1 2 1 -0.0036 12 0 0 0 7.72E+07 7.33E+07 - - - 0.9961 0.9843 221125_WJC_METTL3_EV_vs_WT_F10.08063.08063.2 0.00239 16-Dec Y.VVERPSTTK.D "sp|Q9NYF8|BCLF1_HUMAN,tr|E9PKI6|E9PKI6_HUMAN,tr|A0A1W2PQ43|A0A1W2PQ43_HUMAN,tr|E9PK91|E9PK91_HUMAN,tr|E9PK09|E9PK09_HUMAN,tr|E9PQN2|E9PQN2_HUMAN" 6 1015.5662 1.64 140764 8063 2 1015.564111 508.7904 Bcl-2-associated transcription factor 1 OS=Homo sapiens OX=9606 GN=BCLAF1 PE=1 SV=2 8.72 1859.4 - 1.67E+06 - - - -2.0658 - 2.325 0.464 - 448.5 1 1 0 -0.0021 9 0 0 0 1.38E+08 8.42E+07 - - - 4.9084 0.9997 221125_WJC_METTL3_EV_vs_WT_F10.08064.08064.3 0.000433 Nov-64 K.QQTPPSQQQPLHQPAMK.S "sp|Q8NDV7|TNR6A_HUMAN,tr|H3BTQ1|H3BTQ1_HUMAN,tr|H7C269|H7C269_HUMAN" 3 1942.9683 6.25 140765 8064 3 1942.970897 648.6634 Trinucleotide repeat-containing gene 6A protein OS=Homo sapiens OX=9606 GN=TNRC6A PE=1 SV=2 8.76 1859.6 - 417187 - - - 1.3212 - 1.721 0.402 - 69.7 1 2 0 0.0026 17 0 0 0 1.87E+07 2.99E+06 - - - 4.3927 1 221125_WJC_METTL3_EV_vs_WT_F10.08067.08067.4 1.07E-07 20/108 K.VASEAPLEHK[136.11]PQVEASSPR[166.11].L "sp|Q8TD19|NEK9_HUMAN,tr|A0A7I2V5R1|A0A7I2V5R1_HUMAN,tr|A0A7I2V454|A0A7I2V454_HUMAN" 3 2049.061 0.53 140766 8067 4 2049.056387 513.2725 Serine\threonine-protein kinase Nek9 OS=Homo sapiens OX=9606 GN=NEK9 PE=1 SV=2 5.5 1860 - 644591 - - - -2.2454 - 3.727 0.514 - 277.2 1 2 0 -0.0046 19 0 0 0 1.66E+07 3.14E+07 - - - 4.1436 0.9998 221125_WJC_METTL3_EV_vs_WT_F10.08069.08069.3 1.39E-06 14/60 R.MVQEAEK[136.11]YK[136.11]AEDEVQR[166.11].E "sp|P0DMV8|HS71A_HUMAN,sp|P0DMV9|HS71B_HUMAN,tr|V9GZ37|V9GZ37_HUMAN,tr|A0A0G2JIW1|A0A0G2JIW1_HUMAN" 4 1977.9676 0.01 140767 8069 3 1977.962646 660.3298 Heat shock 70 kDa protein 1A OS=Homo sapiens OX=9606 GN=HSPA1A PE=1 SV=1 4.58 1860.2 - 288374 - - - -2.5102 - 2.443 0.577 - 228.8 1 2 2 -0.005 16 0 0 0 1.75E+05 1.69E+07 - - - 7.2635 0.9624 221125_WJC_METTL3_EV_vs_WT_F10.08070.08070.2 0.0649 20-Jul T.GYVVERPSTTK.D "sp|Q9NYF8|BCLF1_HUMAN,tr|E9PKI6|E9PKI6_HUMAN,tr|A0A1W2PQ43|A0A1W2PQ43_HUMAN,tr|E9PK91|E9PK91_HUMAN,tr|E9PK09|E9PK09_HUMAN,tr|E9PQN2|E9PQN2_HUMAN" 6 1235.651 9 140768 8070 2 1235.649242 618.8328 Bcl-2-associated transcription factor 1 OS=Homo sapiens OX=9606 GN=BCLAF1 PE=1 SV=2 8.59 1860.3 - 141127 - - - -1.4235 - 1.687 0.366 - 173.2 1 1 0 -0.0018 11 0 0 0 5.00E+06 5.56E+05 - - - 3.1584 0.997 221125_WJC_METTL3_EV_vs_WT_F10.08071.08071.3 0.000621 Dec-52 K.RGGNRFEPYANPTK.R "sp|P52272|HNRPM_HUMAN,tr|M0R019|M0R019_HUMAN,tr|M0R0Y6|M0R0Y6_HUMAN,tr|M0R0N3|M0R0N3_HUMAN,tr|A0A087X0X3|A0A087X0X3_HUMAN,tr|M0QYQ7|M0QYQ7_HUMAN,tr|M0R2T0|M0R2T0_HUMAN" 7 1605.8012 1.63 140769 8071 3 1605.79767 536.2743 Heterogeneous nuclear ribonucleoprotein M OS=Homo sapiens OX=9606 GN=HNRNPM PE=1 SV=3 9.99 1860.4 - 1.24E+06 - - - -2.1908 - 2.127 0.326 - 144.4 1 2 1 -0.0035 14 0 0 0 3.64E+07 2.23E+07 - - - 4.1793 0.9998 221125_WJC_METTL3_EV_vs_WT_F10.08075.08075.3 2.38E-08 17/44 K.NFREEPEHDFSK.L "sp|O75410|TACC1_HUMAN,tr|E5RFM9|E5RFM9_HUMAN,tr|R4GMT7|R4GMT7_HUMAN" 3 1533.6848 1.01 140771 8075 3 1533.682323 512.2356 Transforming acidic coiled-coil-containing protein 1 OS=Homo sapiens OX=9606 GN=TACC1 PE=1 SV=2 4.83 1860.9 - 669618 - - - -1.6288 - 3.116 0.444 - 437.5 1 2 1 -0.0025 12 0 0 0 1.01E+08 1.00E+08 - - - 6.6398 1 221125_WJC_METTL3_EV_vs_WT_F10.08077.08077.3 1.10E-09 20/52 K.HELQANC[160.03]YEEVKDR.C "sp|P23528|COF1_HUMAN,tr|E9PP50|E9PP50_HUMAN,tr|G3V1A4|G3V1A4_HUMAN,tr|E9PK25|E9PK25_HUMAN" 4 1789.8053 1.33 140772 8077 3 1789.802067 597.6091 Cofilin-1 OS=Homo sapiens OX=9606 GN=CFL1 PE=1 SV=3 4.83 1861.1 - 2.74E+06 - - - -1.8326 - 3.855 0.591 - 852.5 1 2 1 -0.0033 14 0 0 0 5.14E+08 3.88E+08 - - - 8.7142 1 221125_WJC_METTL3_EV_vs_WT_F10.08081.08081.3 1.72E-13 23/52 K.HELQANC[160.03]YEEVK[136.11]DR[166.11].C "sp|P23528|COF1_HUMAN,tr|E9PP50|E9PP50_HUMAN,tr|G3V1A4|G3V1A4_HUMAN,tr|E9PK25|E9PK25_HUMAN" 4 1807.8278 1.33 140774 8081 3 1807.822858 603.6165 Cofilin-1 OS=Homo sapiens OX=9606 GN=CFL1 PE=1 SV=3 4.83 1861.7 - 3.33E+06 - - - -2.7431 - 4.116 0.747 - 1118.5 1 2 1 -0.005 14 0 0 0 5.14E+08 3.87E+08 - - - 10.627 0.9999 221125_WJC_METTL3_EV_vs_WT_F10.08083.08083.3 0.000335 16/72 K.VAQPPLSAQATGSGQPTR[166.11]K[136.11].A "sp|Q86UK7|ZN598_HUMAN,tr|H3BR87|H3BR87_HUMAN,tr|H3BQQ2|H3BQQ2_HUMAN,tr|H3BPG6|H3BPG6_HUMAN" 4 1911.0293 0.47 140776 8083 3 1911.024036 638.017 E3 ubiquitin-protein ligase ZNF598 OS=Homo sapiens OX=9606 GN=ZNF598 PE=1 SV=1 11 1861.9 - 339629 - - - -2.7514 - 2.839 0.458 - 181.7 1 2 0 -0.0053 19 0 0 0 5.83E+06 1.24E+07 - - - 6.2083 0.9999 221125_WJC_METTL3_EV_vs_WT_F10.08087.08087.4 1.59E-07 13/78 K.HELQANC[160.03]YEEVK[136.11]DR[166.11].C "sp|P23528|COF1_HUMAN,tr|E9PP50|E9PP50_HUMAN,tr|G3V1A4|G3V1A4_HUMAN,tr|E9PK25|E9PK25_HUMAN" 4 1807.8278 1.1 140778 8087 4 1807.824942 452.9642 Cofilin-1 OS=Homo sapiens OX=9606 GN=CFL1 PE=1 SV=3 4.83 1862.3 - 1.75E+06 - - - -1.5903 - 2.741 0.558 - 212.4 1 2 1 -0.0029 14 0 0 0 2.41E+08 2.20E+08 - - - 4.449 0.9988 221125_WJC_METTL3_EV_vs_WT_F10.08088.08088.3 0.000245 14/44 K.NFR[166.11]EEPEHDFSK[136.11].L "sp|O75410|TACC1_HUMAN,tr|E5RFM9|E5RFM9_HUMAN,tr|R4GMT7|R4GMT7_HUMAN" 3 1551.7073 0.93 140779 8088 3 1551.70145 518.243 Transforming acidic coiled-coil-containing protein 1 OS=Homo sapiens OX=9606 GN=TACC1 PE=1 SV=2 4.83 1862.4 - 1.53E+06 - - - -3.7642 - 2.386 0.467 - 276 1 2 1 -0.0058 12 0 0 0 1.01E+08 1.09E+08 - - - 6.1554 0.9986 221125_WJC_METTL3_EV_vs_WT_F10.08089.08089.4 0.00508 18/78 R.AIEALHGHELRPGR.A "sp|Q96PK6|RBM14_HUMAN,tr|B8ZZ74|B8ZZ74_HUMAN,tr|F8WDX3|F8WDX3_HUMAN,tr|A0A0A0MSL8|A0A0A0MSL8_HUMAN,tr|A0A0A6YYI9|A0A0A6YYI9_HUMAN" 5 1554.8379 1.77 140780 8089 4 1554.833023 389.7168 RNA-binding protein 14 OS=Homo sapiens OX=9606 GN=RBM14 PE=1 SV=2 6.97 1862.5 - 1.31E+06 - - - -3.1418 - 2.517 0.332 - 318.1 1 2 0 -0.0049 14 0 0 0 1.57E+09 8.86E+08 - - - 2.4503 0.9966 221125_WJC_METTL3_EV_vs_WT_F10.08095.08095.3 6.52E-06 17/48 K.TDR[166.11]PLPENPYHSR[166.11].P sp|P51970|NDUA8_HUMAN 1 1600.7861 1.53 140783 8095 3 1600.783282 534.6026 NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 8 OS=Homo sapiens OX=9606 GN=NDUFA8 PE=1 SV=3 6.42 1863.2 - 616983 - - - -1.7566 - 2.764 0.51 - 572 1 1 0 -0.0028 13 0 0 0 4.77E+07 3.13E+07 - - - 6.9817 1 221125_WJC_METTL3_EV_vs_WT_F10.08097.08097.3 5.47E-05 17/52 R.AIEALHGHELR[166.11]PGR[166.11].A "sp|Q96PK6|RBM14_HUMAN,tr|B8ZZ74|B8ZZ74_HUMAN,tr|F8WDX3|F8WDX3_HUMAN,tr|A0A0A0MSL8|A0A0A0MSL8_HUMAN,tr|A0A0A6YYI9|A0A0A6YYI9_HUMAN" 5 1574.8544 1.77 140784 8097 3 1574.852504 525.9588 RNA-binding protein 14 OS=Homo sapiens OX=9606 GN=RBM14 PE=1 SV=2 6.97 1863.4 - 927562 - - - -1.2344 - 2.729 0.495 - 466.6 1 2 0 -0.0019 14 0 0 0 6.95E+08 3.92E+08 - - - 6.7262 0.9999 221125_WJC_METTL3_EV_vs_WT_F10.08099.08099.4 0.00125 18/78 R.AIEALHGHELR[166.11]PGR[166.11].A "sp|Q96PK6|RBM14_HUMAN,tr|B8ZZ74|B8ZZ74_HUMAN,tr|F8WDX3|F8WDX3_HUMAN,tr|A0A0A0MSL8|A0A0A0MSL8_HUMAN,tr|A0A0A6YYI9|A0A0A6YYI9_HUMAN" 5 1574.8544 1.77 140785 8099 4 1574.851223 394.7209 RNA-binding protein 14 OS=Homo sapiens OX=9606 GN=RBM14 PE=1 SV=2 6.97 1863.6 - 2.55E+06 - - - -2.0478 - 2.579 0.425 - 302.1 1 2 0 -0.0032 14 0 0 0 1.57E+09 8.87E+08 - - - 3.2691 0.9993 221125_WJC_METTL3_EV_vs_WT_F10.08100.08100.4 0.0127 15/72 R.YNLHQIQGHSAPR.H sp|O75319|DUS11_HUMAN 1 1519.7644 1.23 140786 8100 4 1519.760862 380.9484 RNA\RNP complex-1-interacting phosphatase OS=Homo sapiens OX=9606 GN=DUSP11 PE=1 SV=2 8.76 1863.7 - 576293 - - - -2.3339 - 2.124 0.346 - 121.5 1 2 0 -0.0035 13 0 0 0 4.76E+07 3.87E+07 - - - 2.5159 0.9251 221125_WJC_METTL3_EV_vs_WT_F10.08103.08103.2 0.399 14-Oct V.VER[166.11]PSTTK[136.11].D "sp|Q9NYF8|BCLF1_HUMAN,tr|E9PKI6|E9PKI6_HUMAN,tr|A0A1W2PQ43|A0A1W2PQ43_HUMAN,tr|E9PK91|E9PK91_HUMAN,tr|E9PK09|E9PK09_HUMAN,tr|E9PQN2|E9PQN2_HUMAN" 6 934.5203 2.17 140787 8103 2 934.519477 468.2674 Bcl-2-associated transcription factor 1 OS=Homo sapiens OX=9606 GN=BCLAF1 PE=1 SV=2 8.72 1864.1 - 2.18E+06 - - - -0.8432 - 2.1 0.127 - 307.8 1 1 0 -0.0008 8 0 0 0 2.24E+08 1.04E+08 - - - 2.2164 0.9998 221125_WJC_METTL3_EV_vs_WT_F10.08105.08105.3 0.000303 13/52 R.AIEALHGHELRPGR.A "sp|Q96PK6|RBM14_HUMAN,tr|B8ZZ74|B8ZZ74_HUMAN,tr|F8WDX3|F8WDX3_HUMAN,tr|A0A0A0MSL8|A0A0A0MSL8_HUMAN,tr|A0A0A6YYI9|A0A0A6YYI9_HUMAN" 5 1554.8379 1.77 140788 8105 3 1554.833795 519.2866 RNA-binding protein 14 OS=Homo sapiens OX=9606 GN=RBM14 PE=1 SV=2 6.97 1864.3 - 2.36E+06 - - - -2.6453 - 2.94 0.385 - 233.8 1 2 0 -0.0041 14 0 0 0 6.94E+08 3.92E+08 - - - 5.6971 1 221125_WJC_METTL3_EV_vs_WT_F10.08111.08111.4 9.13E-10 16/78 K.HELQANC[160.03]YEEVKDR.C "sp|P23528|COF1_HUMAN,tr|E9PP50|E9PP50_HUMAN,tr|G3V1A4|G3V1A4_HUMAN,tr|E9PK25|E9PK25_HUMAN" 4 1789.8053 1.11 140791 8111 4 1789.801716 448.4586 Cofilin-1 OS=Homo sapiens OX=9606 GN=CFL1 PE=1 SV=3 4.83 1865.1 - 7.22E+06 - - - -2.0287 - 2.961 0.637 - 340 1 2 1 -0.0036 14 0 0 0 2.40E+08 2.17E+08 - - - 5.1645 1 221125_WJC_METTL3_EV_vs_WT_F10.08115.08115.3 5.95E-06 Dec-52 K.VETSDEEIHDLHQR[166.11].L "sp|P07099|HYEP_HUMAN,tr|B1AQP8|B1AQP8_HUMAN" 2 1716.7943 0.001 140793 8115 3 1716.793259 573.272 Epoxide hydrolase 1 OS=Homo sapiens OX=9606 GN=EPHX1 PE=1 SV=1 4.49 1865.5 - 389971 - - - -0.5836 - 2.435 0.562 - 207 1 2 0 -0.001 14 0 0 0 0.00E+00 1.13E+07 - - - 7.1705 0.929 221125_WJC_METTL3_EV_vs_WT_F10.08118.08118.2 0.000346 18-Sep G.YVVERPSTTK.D "sp|Q9NYF8|BCLF1_HUMAN,tr|E9PKI6|E9PKI6_HUMAN,tr|A0A1W2PQ43|A0A1W2PQ43_HUMAN,tr|E9PK91|E9PK91_HUMAN,tr|E9PK09|E9PK09_HUMAN,tr|E9PQN2|E9PQN2_HUMAN" 6 1178.6295 3.59 140794 8118 2 1178.625883 590.322 Bcl-2-associated transcription factor 1 OS=Homo sapiens OX=9606 GN=BCLAF1 PE=1 SV=2 8.59 1865.9 - 349032 - - - -3.1011 - 1.813 0.41 - 180.5 1 1 0 -0.0037 10 0 0 0 1.51E+07 4.21E+06 - - - 3.7289 0.9912 221125_WJC_METTL3_EV_vs_WT_F10.08128.08128.3 5.58E-05 13/44 L.EALHGHELR[166.11]PGR[166.11].A "sp|Q96PK6|RBM14_HUMAN,tr|B8ZZ74|B8ZZ74_HUMAN,tr|F8WDX3|F8WDX3_HUMAN,tr|A0A0A0MSL8|A0A0A0MSL8_HUMAN,tr|A0A0A6YYI9|A0A0A6YYI9_HUMAN" 5 1390.7333 1.7 140798 8128 3 1390.73065 464.585 RNA-binding protein 14 OS=Homo sapiens OX=9606 GN=RBM14 PE=1 SV=2 7.02 1867.1 - 2.49E+06 - - - -1.8839 - 2.103 0.475 - 229.6 1 1 0 -0.0026 12 0 0 0 2.62E+08 1.54E+08 - - - 5.8956 0.9897 221125_WJC_METTL3_EV_vs_WT_F10.08135.08135.3 0.00016 17/44 L.EALHGHELRPGR.A "sp|Q96PK6|RBM14_HUMAN,tr|B8ZZ74|B8ZZ74_HUMAN,tr|F8WDX3|F8WDX3_HUMAN,tr|A0A0A0MSL8|A0A0A0MSL8_HUMAN,tr|A0A0A6YYI9|A0A0A6YYI9_HUMAN" 5 1370.7167 1.71 140803 8135 3 1370.713275 457.9129 RNA-binding protein 14 OS=Homo sapiens OX=9606 GN=RBM14 PE=1 SV=2 7.02 1868.1 - 7.22E+06 - - - -2.5206 - 2.345 0.478 - 333.3 1 1 0 -0.0035 12 0 0 0 2.62E+08 1.53E+08 - - - 6.2307 1 221125_WJC_METTL3_EV_vs_WT_F10.08136.08136.3 9.48E-10 20/48 R.SK[136.11]VEETTEHLVTK[136.11].S "sp|P52732|KIF11_HUMAN,tr|A0A7I2V3A9|A0A7I2V3A9_HUMAN" 2 1515.8115 4.4 140804 8136 3 1515.808657 506.2778 Kinesin-like protein KIF11 OS=Homo sapiens OX=9606 GN=KIF11 PE=1 SV=2 5.47 1868.1 - 2.37E+06 - - - -1.9006 - 4.042 0.667 - 333.4 1 2 1 -0.0029 13 0 0 0 3.67E+09 8.34E+08 - - - 9.7626 0.9776 221125_WJC_METTL3_EV_vs_WT_F10.08137.08137.3 1.38E-05 16/48 A.IEALHGHELRPGR.A "sp|Q96PK6|RBM14_HUMAN,tr|B8ZZ74|B8ZZ74_HUMAN,tr|F8WDX3|F8WDX3_HUMAN,tr|A0A0A0MSL8|A0A0A0MSL8_HUMAN,tr|A0A0A6YYI9|A0A0A6YYI9_HUMAN" 5 1483.8008 3.14 140805 8137 3 1483.797107 495.6075 RNA-binding protein 14 OS=Homo sapiens OX=9606 GN=RBM14 PE=1 SV=2 6.93 1868.2 - 1.52E+06 - - - -2.4848 - 2.617 0.377 - 497.5 1 1 0 -0.0037 13 0 0 0 6.56E+07 2.09E+07 - - - 5.3505 1 221125_WJC_METTL3_EV_vs_WT_F10.08138.08138.2 8.18E-08 16/24 R.SKVEETTEHLVTK.S "sp|P52732|KIF11_HUMAN,tr|A0A7I2V3A9|A0A7I2V3A9_HUMAN" 2 1499.7831 4.51 140806 8138 2 1499.781585 750.8988 Kinesin-like protein KIF11 OS=Homo sapiens OX=9606 GN=KIF11 PE=1 SV=2 5.47 1868.4 - 541405 - - - -1.0355 - 3.191 0.614 - 698.1 1 2 1 -0.0016 13 0 0 0 2.22E+08 4.93E+07 - - - 6.5535 0.9999 221125_WJC_METTL3_EV_vs_WT_F10.08141.08141.4 1.69E-06 13/72 R.YNLHQIQGHSAPR[166.11].H sp|O75319|DUS11_HUMAN 1 1529.7727 1.23 140807 8141 4 1529.769245 383.4504 RNA\RNP complex-1-interacting phosphatase OS=Homo sapiens OX=9606 GN=DUSP11 PE=1 SV=2 8.76 1868.8 - 2.34E+06 - - - -2.2448 - 2.78 0.464 - 90 1 2 0 -0.0034 13 0 0 0 4.76E+07 3.87E+07 - - - 3.6428 0.9999 221125_WJC_METTL3_EV_vs_WT_F10.08143.08143.3 9.65E-07 18/48 R.RESLSTSSDLYKR.S sp|Q8TB72|PUM2_HUMAN 1 1540.7845 9.11 140809 8143 3 1540.780691 514.6021 Pumilio homolog 2 OS=Homo sapiens OX=9606 GN=PUM2 PE=1 SV=2 8.59 1869 - 473248 - - - -2.4948 - 3.392 0.434 - 721.7 1 2 0 -0.0038 13 0 0 0 6.36E+06 6.98E+05 - - - 6.6892 1 221125_WJC_METTL3_EV_vs_WT_F10.08146.08146.2 7.71E-05 14/24 R.SK[136.11]VEETTEHLVTK[136.11].S "sp|P52732|KIF11_HUMAN,tr|A0A7I2V3A9|A0A7I2V3A9_HUMAN" 2 1515.8115 4.51 140810 8146 2 1515.808903 758.913 Kinesin-like protein KIF11 OS=Homo sapiens OX=9606 GN=KIF11 PE=1 SV=2 5.47 1869.4 - 437252 - - - -1.7383 - 3.038 0.56 - 526 1 2 1 -0.0026 13 0 0 0 2.22E+08 4.93E+07 - - - 6.0283 0.8931 221125_WJC_METTL3_EV_vs_WT_F10.08148.08148.4 0.0206 16/78 R.AIEALHGHELR[166.11]PGR.A "sp|Q96PK6|RBM14_HUMAN,tr|B8ZZ74|B8ZZ74_HUMAN,tr|F8WDX3|F8WDX3_HUMAN,tr|A0A0A0MSL8|A0A0A0MSL8_HUMAN,tr|A0A0A6YYI9|A0A0A6YYI9_HUMAN" 5 1564.8462 - 140811 8148 4 1564.843294 392.2188 RNA-binding protein 14 OS=Homo sapiens OX=9606 GN=RBM14 PE=1 SV=2 6.97 1869.6 - 481179 - - - -1.843 - 2.413 0.13 - 210.9 2 2 0 -0.0029 14 0 0 0 - - - - - 0.4479 1 221125_WJC_METTL3_EV_vs_WT_F10.08149.08149.3 4.98E-11 19/72 K.DAQQVEPEGQEKPSPATVR.S "sp|Q9Y520|PRC2C_HUMAN,tr|E7EPN9|E7EPN9_HUMAN,tr|H7C5N8|H7C5N8_HUMAN,tr|A0A2R8Y7F4|A0A2R8Y7F4_HUMAN,tr|A0A2R8YET2|A0A2R8YET2_HUMAN" 5 2065.0076 2.3 140812 8149 3 2065.002778 689.3431 Protein PRRC2C OS=Homo sapiens OX=9606 GN=PRRC2C PE=1 SV=4 4.41 1869.8 - 556591 - - - -2.3409 - 3.452 0.664 - 415.1 1 2 0 -0.0048 19 0 0 0 9.09E+07 3.96E+07 - - - 8.9855 0.9999 221125_WJC_METTL3_EV_vs_WT_F10.08152.08152.3 2.26E-06 Dec-64 R.ISPPIKEEETKGDSVEK.N "sp|Q6PJT7|ZC3HE_HUMAN,tr|G3V256|G3V256_HUMAN,tr|G3V5I6|G3V5I6_HUMAN,tr|H0YJA2|H0YJA2_HUMAN,tr|A0A087WTC9|A0A087WTC9_HUMAN" 5 1884.968 0.81 140813 8152 3 1884.970262 629.33 Zinc finger CCCH domain-containing protein 14 OS=Homo sapiens OX=9606 GN=ZC3H14 PE=1 SV=1 4.59 1870.1 - 332154 - - - 1.1799 - 2.681 0.534 - 139.7 1 2 2 0.0022 17 0 0 0 2.79E+07 3.45E+07 - - - 6.9844 0.9998 221125_WJC_METTL3_EV_vs_WT_F10.08153.08153.2 0.000131 26-Oct R.AIEALHGHELRPGR.A "sp|Q96PK6|RBM14_HUMAN,tr|B8ZZ74|B8ZZ74_HUMAN,tr|F8WDX3|F8WDX3_HUMAN,tr|A0A0A0MSL8|A0A0A0MSL8_HUMAN,tr|A0A0A6YYI9|A0A0A6YYI9_HUMAN" 5 1554.8379 3.09 140814 8153 2 1554.837395 778.4262 RNA-binding protein 14 OS=Homo sapiens OX=9606 GN=RBM14 PE=1 SV=2 6.97 1870.3 - 230655 - - - -0.3299 - 2.017 0.471 - 100.7 1 2 0 -0.0005 14 0 0 0 5.84E+06 1.89E+06 - - - 4.2803 0.8991 221125_WJC_METTL3_EV_vs_WT_F10.08158.08158.4 5.21E-07 17/72 R.SK[136.11]VEETTEHLVTK[136.11].S "sp|P52732|KIF11_HUMAN,tr|A0A7I2V3A9|A0A7I2V3A9_HUMAN" 2 1515.8115 0.001 140817 8158 4 1516.809863 379.9602 Kinesin-like protein KIF11 OS=Homo sapiens OX=9606 GN=KIF11 PE=1 SV=2 5.47 1870.9 - 2.48E+06 - - - 658.6076 - 3.169 0.386 - 239.4 1 2 1 0.9983 13 0 0 0 0.00E+00 5.08E+06 - - - 2.7369 1 221125_WJC_METTL3_EV_vs_WT_F10.08165.08165.4 7.94E-06 17/78 R.NVQRPESVSDHMYR.M "sp|Q7Z4H3|HDDC2_HUMAN,tr|V9GZ04|V9GZ04_HUMAN,tr|V9GYS5|V9GYS5_HUMAN" 3 1716.8002 2.37 140822 8165 4 1716.800365 430.2073 5'-deoxynucleotidase HDDC2 OS=Homo sapiens OX=9606 GN=HDDC2 PE=1 SV=1 6.75 1871.9 - 919309 - - - 0.0949 - 2.653 0.489 - 298.1 1 2 0 0.0002 14 0 0 0 4.25E+07 1.79E+07 - - - 3.8373 0.9995 221125_WJC_METTL3_EV_vs_WT_F10.08167.08167.3 1.15E-05 17/48 R.SKVEETTEHLVTK[136.11].S "sp|P52732|KIF11_HUMAN,tr|A0A7I2V3A9|A0A7I2V3A9_HUMAN" 2 1507.7973 - 140824 8167 3 1507.794339 503.6064 Kinesin-like protein KIF11 OS=Homo sapiens OX=9606 GN=KIF11 PE=1 SV=2 5.47 1872.1 - 1.09E+06 - - - -1.989 - 2.442 0.431 - 193 1 2 1 -0.003 13 0 0 0 - - - - - 5.7651 1 221125_WJC_METTL3_EV_vs_WT_F10.08168.08168.3 4.23E-07 19/72 K.DAQQVEPEGQEK[136.11]PSPATVR[166.11].S "sp|Q9Y520|PRC2C_HUMAN,tr|E7EPN9|E7EPN9_HUMAN,tr|H7C5N8|H7C5N8_HUMAN,tr|A0A2R8Y7F4|A0A2R8Y7F4_HUMAN,tr|A0A2R8YET2|A0A2R8YET2_HUMAN" 5 2083.0301 2.28 140825 8168 3 2083.02775 695.3506 Protein PRRC2C OS=Homo sapiens OX=9606 GN=PRRC2C PE=1 SV=4 4.41 1872.2 - 846109 - - - -1.1195 - 3.291 0.6 - 385.1 1 2 0 -0.0023 19 0 0 0 9.13E+07 4.01E+07 - - - 8.1553 0.9387 221125_WJC_METTL3_EV_vs_WT_F10.08172.08172.3 0.000218 Nov-48 D.AHPTLVTYADHSK[136.11].L "sp|Q86U44|MTA70_HUMAN,tr|F5H6D8|F5H6D8_HUMAN,tr|H0YFV6|H0YFV6_HUMAN,tr|B4DTN4|B4DTN4_HUMAN" 4 1446.7347 0.05 140827 8172 3 1446.728427 483.2522 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 6.96 1872.7 - 537472 - - - -4.3208 - 2.309 0.435 - 182.5 1 1 0 -0.0063 13 0 0 0 8.10E+05 1.60E+07 - - - 5.6569 1 221125_WJC_METTL3_EV_vs_WT_F10.08175.08175.2 5.13E-05 14/20 K.VEETTEHLVTK.S "sp|P52732|KIF11_HUMAN,tr|A0A7I2V3A9|A0A7I2V3A9_HUMAN" 2 1284.6561 15.87 140830 8175 2 1284.654083 643.3353 Kinesin-like protein KIF11 OS=Homo sapiens OX=9606 GN=KIF11 PE=1 SV=2 4.75 1873 - 552204 - - - -1.6059 - 2.948 0.555 - 705.6 1 2 0 -0.0021 11 0 0 0 1.30E+07 8.20E+05 - - - 6.0643 0.9994 221125_WJC_METTL3_EV_vs_WT_F10.08181.08181.3 4.95E-06 Oct-64 R.ISPPIK[136.11]EEETK[136.11]GDSVEK[136.11].N "sp|Q6PJT7|ZC3HE_HUMAN,tr|G3V256|G3V256_HUMAN,tr|G3V5I6|G3V5I6_HUMAN,tr|H0YJA2|H0YJA2_HUMAN,tr|A0A087WTC9|A0A087WTC9_HUMAN" 5 1909.0106 1.21 140834 8181 3 1909.006005 637.3442 Zinc finger CCCH domain-containing protein 14 OS=Homo sapiens OX=9606 GN=ZC3H14 PE=1 SV=1 4.59 1873.8 - 424589 - - - -2.4269 - 2.156 0.48 - 104.6 1 2 2 -0.0046 17 0 0 0 1.57E+07 1.30E+07 - - - 5.8311 0.9999 221125_WJC_METTL3_EV_vs_WT_F10.08182.08182.4 0.000762 15/78 R.NVQR[166.11]PESVSDHMYR[166.11].M "sp|Q7Z4H3|HDDC2_HUMAN,tr|V9GZ04|V9GZ04_HUMAN,tr|V9GYS5|V9GYS5_HUMAN" 3 1736.8167 3.14 140835 8182 4 1736.814487 435.2115 5'-deoxynucleotidase HDDC2 OS=Homo sapiens OX=9606 GN=HDDC2 PE=1 SV=1 6.75 1874 - 851180 - - - -1.2984 - 2.575 0.407 - 245.8 1 2 0 -0.0023 14 0 0 0 5.98E+07 1.91E+07 - - - 3.1121 0.9998 221125_WJC_METTL3_EV_vs_WT_F10.08187.08187.4 0.0019 Nov-90 K.VKPISLADHC[160.03]TQPGQK.C "sp|O60259|KLK8_HUMAN,tr|A0A0A0MQY9|A0A0A0MQY9_HUMAN" 2 1777.9145 284.38 140838 8187 4 1777.912074 445.4859 Kallikrein-8 OS=Homo sapiens OX=9606 GN=KLK8 PE=1 SV=1 8.18 1874.6 - 731578 - - - -1.3668 - 1.932 0.399 - 39 1 2 0 -0.0024 16 0 0 0 1.17E+07 4.11E+04 - - - 2.9302 0.9982 221125_WJC_METTL3_EV_vs_WT_F10.08188.08188.3 0.0229 13/44 R.NMSVIAHVDHGK[136.11].S sp|P13639|EF2_HUMAN 1 1314.6594 0.3 140839 8188 3 1314.653952 439.2271 Elongation factor 2 OS=Homo sapiens OX=9606 GN=EEF2 PE=1 SV=4 6.92 1874.7 - 429657 - - - -4.1478 - 1.905 0.379 - 195.9 1 2 0 -0.0055 12 0 0 0 3.05E+06 1.02E+07 - - - 4.5504 0.9999 221125_WJC_METTL3_EV_vs_WT_F10.08190.08190.3 0.0436 Dec-44 K.K[136.11]GQTHTLEDFQR[166.11].V "sp|Q99714|HCD2_HUMAN,tr|Q5H928|Q5H928_HUMAN,tr|A0A804HHW5|A0A804HHW5_HUMAN" 3 1476.744 0.75 140841 8190 3 1476.744384 493.2553 3-hydroxyacyl-CoA dehydrogenase type-2 OS=Homo sapiens OX=9606 GN=HSD17B10 PE=1 SV=3 6.75 1874.9 - 1.32E+06 - - - 0.2526 - 2.324 0.359 - 254.3 1 2 0 0.0004 12 0 0 0 1.64E+07 2.18E+07 - - - 4.8799 0.9999 221125_WJC_METTL3_EV_vs_WT_F10.08195.08195.3 4.46E-06 15/44 K.KGQTHTLEDFQR.V "sp|Q99714|HCD2_HUMAN,tr|Q5H928|Q5H928_HUMAN,tr|A0A804HHW5|A0A804HHW5_HUMAN" 3 1458.7215 0.75 140844 8195 3 1458.718304 487.2478 3-hydroxyacyl-CoA dehydrogenase type-2 OS=Homo sapiens OX=9606 GN=HSD17B10 PE=1 SV=3 6.75 1875.6 - 844449 - - - -2.2191 - 2.84 0.45 - 424.2 1 2 0 -0.0032 12 0 0 0 1.65E+07 2.19E+07 - - - 6.4494 1 221125_WJC_METTL3_EV_vs_WT_F10.08196.08196.3 3.74E-07 14/60 K.VKPISLADHC[160.03]TQPGQK.C "sp|O60259|KLK8_HUMAN,tr|A0A0A0MQY9|A0A0A0MQY9_HUMAN" 2 1777.9145 999 140845 8196 3 1777.912967 593.6454 Kallikrein-8 OS=Homo sapiens OX=9606 GN=KLK8 PE=1 SV=1 8.18 1875.7 - 499492 - - - -0.8645 - 2.529 0.5 - 116.9 1 2 0 -0.0015 16 0 0 0 7.74E+06 0.00E+00 - - - 6.4948 0.9998 221125_WJC_METTL3_EV_vs_WT_F10.08197.08197.4 9.83E-08 16/96 R.ISPPIK[136.11]EEETK[136.11]GDSVEK[136.11].N "sp|Q6PJT7|ZC3HE_HUMAN,tr|G3V256|G3V256_HUMAN,tr|G3V5I6|G3V5I6_HUMAN,tr|H0YJA2|H0YJA2_HUMAN,tr|A0A087WTC9|A0A087WTC9_HUMAN" 5 1909.0106 1.27 140846 8197 4 1909.007402 478.2599 Zinc finger CCCH domain-containing protein 14 OS=Homo sapiens OX=9606 GN=ZC3H14 PE=1 SV=1 4.59 1875.8 - 1.09E+06 - - - -1.6951 - 3.343 0.495 - 126.3 1 2 2 -0.0032 17 0 0 0 5.46E+07 4.29E+07 - - - 3.9526 1 221125_WJC_METTL3_EV_vs_WT_F10.08198.08198.3 3.17E-07 16/52 R.NVQR[166.11]PESVSDHMYR[166.11].M "sp|Q7Z4H3|HDDC2_HUMAN,tr|V9GZ04|V9GZ04_HUMAN,tr|V9GYS5|V9GYS5_HUMAN" 3 1736.8167 2.26 140847 8198 3 1736.813481 579.9462 5'-deoxynucleotidase HDDC2 OS=Homo sapiens OX=9606 GN=HDDC2 PE=1 SV=1 6.75 1875.9 - 563240 - - - -1.8776 - 2.856 0.571 - 367.6 1 2 0 -0.0033 14 0 0 0 3.01E+07 1.33E+07 - - - 7.6941 1 221125_WJC_METTL3_EV_vs_WT_F10.08199.08199.3 8.11E-10 17/72 K.AAESVSK[136.11]PDVSEEAPGPSK[136.11].V "sp|Q9BY42|RTF2_HUMAN,tr|A0A0A0MQR2|A0A0A0MQR2_HUMAN,tr|A2A2L5|A2A2L5_HUMAN" 3 1899.9397 0.4 140848 8199 3 1899.939296 634.3205 Replication termination factor 2 OS=Homo sapiens OX=9606 GN=RTF2 PE=1 SV=3 4.41 1876.1 - 376234 - - - -0.1874 - 3.188 0.613 - 242.7 1 2 0 -0.0004 19 0 0 0 4.48E+06 1.13E+07 - - - 8.2226 0.9997 221125_WJC_METTL3_EV_vs_WT_F10.08202.08202.4 0.000671 14/96 R.ISPPIKEEETKGDSVEK.N "sp|Q6PJT7|ZC3HE_HUMAN,tr|G3V256|G3V256_HUMAN,tr|G3V5I6|G3V5I6_HUMAN,tr|H0YJA2|H0YJA2_HUMAN,tr|A0A087WTC9|A0A087WTC9_HUMAN" 5 1884.968 1.27 140849 8202 4 1884.966734 472.2493 Zinc finger CCCH domain-containing protein 14 OS=Homo sapiens OX=9606 GN=ZC3H14 PE=1 SV=1 4.59 1876.5 - 1.26E+06 - - - -0.6918 - 2.738 0.444 - 104.5 1 2 2 -0.0013 17 0 0 0 5.46E+07 4.29E+07 - - - 3.4399 1 221125_WJC_METTL3_EV_vs_WT_F10.08204.08204.3 0.0578 18/52 K.SINQQSGAHVELQR.N sp|Q96I24|FUBP3_HUMAN 1 1565.791 2.12 140851 8204 3 1565.788598 522.9376 Far upstream element-binding protein 3 OS=Homo sapiens OX=9606 GN=FUBP3 PE=1 SV=2 6.47 1876.6 - 2.38E+06 - - - -1.5449 - 3.146 0.502 - 322.4 1 2 0 -0.0024 14 0 0 0 4.35E+07 2.05E+07 - - - 7.182 0.9999 221125_WJC_METTL3_EV_vs_WT_F10.08205.08205.3 2.56E-09 16/88 R.GSGGGGPASASGPAASESR[166.11]PLPR[166.11].V sp|Q9Y6J9|TAF6L_HUMAN 1 2042.0044 1.23 140852 8205 3 2041.996027 681.6754 TAF6-like RNA polymerase II p300\CBP-associated factor-associated factor 65 kDa subunit 6L OS=Homo sapiens OX=9606 GN=TAF6L PE=1 SV=1 9.6 1876.7 - 439993 - - - -4.1097 - 2.964 0.641 - 190.5 1 2 0 -0.0084 23 0 0 0 6.60E+07 5.35E+07 - - - 8.2332 1 221125_WJC_METTL3_EV_vs_WT_F10.08206.08206.3 4.74E-07 17/88 R.GSGGGGPASASGPAASESRPLPR.V sp|Q9Y6J9|TAF6L_HUMAN 1 2021.9879 1.23 140853 8206 3 2021.98653 675.0032 TAF6-like RNA polymerase II p300\CBP-associated factor-associated factor 65 kDa subunit 6L OS=Homo sapiens OX=9606 GN=TAF6L PE=1 SV=1 9.6 1876.9 - 388577 - - - -0.6672 - 2.871 0.587 - 295.6 1 2 0 -0.0013 23 0 0 0 6.60E+07 5.35E+07 - - - 7.5583 1 221125_WJC_METTL3_EV_vs_WT_F10.08207.08207.3 0.000336 13/64 K.EESESTAVGQAHSDISK[136.11].D sp|Q02952|AKA12_HUMAN 1 1781.8159 0.44 140854 8207 3 1781.814736 594.9459 A-kinase anchor protein 12 OS=Homo sapiens OX=9606 GN=AKAP12 PE=1 SV=4 4.4 1877 - 335661 - - - -0.6538 - 2.2 0.524 - 119.9 1 2 0 -0.0012 17 0 0 0 2.78E+06 6.26E+06 - - - 6.3736 0.9999 221125_WJC_METTL3_EV_vs_WT_F10.08208.08208.3 0.00956 Dec-56 R.KHFSQAEGSQLDEVR.Q "sp|Q7L5Y9|MAEA_HUMAN,tr|B4DVN3|B4DVN3_HUMAN,tr|B4DQT1|B4DQT1_HUMAN,tr|E7ESC7|E7ESC7_HUMAN,tr|D6RE80|D6RE80_HUMAN" 5 1729.8384 1.68 140855 8208 3 1729.838021 577.6201 E3 ubiquitin-protein transferase MAEA OS=Homo sapiens OX=9606 GN=MAEA PE=1 SV=1 5.45 1877.1 - 282493 - - - -0.1966 - 2.467 0.371 - 269.4 1 2 0 -0.0003 15 0 0 0 4.49E+06 2.68E+06 - - - 5.0325 0.7992 221125_WJC_METTL3_EV_vs_WT_F10.08217.08217.4 2.09 Nov-78 K.NPSDSAVHSPFTKR.Q "sp|Q14157|UBP2L_HUMAN,tr|F8W726|F8W726_HUMAN" 2 1541.7587 2.17 140860 8217 4 1541.764204 386.4469 Ubiquitin-associated protein 2-like OS=Homo sapiens OX=9606 GN=UBAP2L PE=1 SV=2 8.75 1878.3 - 245501 - - - 3.5998 - 1.68 0.139 - 73.2 1 2 0 0.0055 14 0 0 0 4.43E+07 2.04E+07 - - - 0.6231 1 221125_WJC_METTL3_EV_vs_WT_F10.08219.08219.3 1.62E-08 30/88 A.YDPEAASAPGSGNPC[160.03]HEASAAQK.E sp|P81605|DCD_HUMAN 1 2313.992 3922.66 140862 8219 3 2313.991711 772.338 Dermcidin OS=Homo sapiens OX=9606 GN=DCD PE=1 SV=2 4.65 1878.6 - 1.48E+06 - - - -0.1413 - 4.278 0.616 - 751.3 1 1 0 -0.0003 23 0 0 0 1.18E+09 3.02E+05 - - - 8.8175 0.9956 221125_WJC_METTL3_EV_vs_WT_F10.08220.08220.2 0.00107 26-Aug K.MK[136.11]ETAENYLGHTAK[136.11].N "sp|P38646|GRP75_HUMAN,tr|H0Y8K0|H0Y8K0_HUMAN,tr|A0A7I2V2S7|A0A7I2V2S7_HUMAN,tr|A0A7I2V2G2|A0A7I2V2G2_HUMAN,tr|A0A7I2V3F7|A0A7I2V3F7_HUMAN,tr|A0A7I2YQB2|A0A7I2YQB2_HUMAN,tr|D6RCD7|D6RCD7_HUMAN" 7 1607.7948 0.25 140863 8220 2 1607.793762 804.9047 "Stress-70 protein, mitochondrial OS=Homo sapiens OX=9606 GN=HSPA9 PE=1 SV=2" 6.51 1878.7 - 130120 - - - -0.6717 - 1.634 0.416 - 126.8 1 2 1 -0.0011 14 0 0 0 7.28E+05 2.92E+06 - - - 3.3455 1 221125_WJC_METTL3_EV_vs_WT_F10.08223.08223.3 7.74E-10 18/52 K.MKETAENYLGHTAK.N "sp|P38646|GRP75_HUMAN,tr|H0Y8K0|H0Y8K0_HUMAN,tr|A0A7I2V2S7|A0A7I2V2S7_HUMAN,tr|A0A7I2V2G2|A0A7I2V2G2_HUMAN,tr|A0A7I2V3F7|A0A7I2V3F7_HUMAN,tr|A0A7I2YQB2|A0A7I2YQB2_HUMAN,tr|D6RCD7|D6RCD7_HUMAN" 7 1591.7664 0.33 140864 8223 3 1591.767023 531.5961 "Stress-70 protein, mitochondrial OS=Homo sapiens OX=9606 GN=HSPA9 PE=1 SV=2" 6.51 1879.1 - 2.49E+06 - - - 0.365 - 3.556 0.619 - 384.2 1 2 1 0.0006 14 0 0 0 5.68E+07 1.71E+08 - - - 8.8125 0.9996 221125_WJC_METTL3_EV_vs_WT_F10.08226.08226.3 0.000229 Sep-48 R.SNEKEQLQGLNDR.F "sp|P07197|NFM_HUMAN,tr|E7ESP9|E7ESP9_HUMAN,tr|E7EMV2|E7EMV2_HUMAN" 3 1529.7434 2.67 140867 8226 3 1529.741645 510.9217 Neurofilament medium polypeptide OS=Homo sapiens OX=9606 GN=NEFM PE=1 SV=3 4.68 1879.4 - 256377 - - - -1.1459 - 2.184 0.423 - 109.1 1 2 1 -0.0018 13 0 0 0 2.17E+07 8.12E+06 - - - 5.3735 0.9997 221125_WJC_METTL3_EV_vs_WT_F10.08228.08228.3 0.0013 Aug-56 R.K[136.11]HFSQAEGSQLDEVR[166.11].Q "sp|Q7L5Y9|MAEA_HUMAN,tr|B4DVN3|B4DVN3_HUMAN,tr|B4DQT1|B4DQT1_HUMAN,tr|E7ESC7|E7ESC7_HUMAN,tr|D6RE80|D6RE80_HUMAN" 5 1747.8608 1.68 140869 8228 3 1747.856871 583.6276 E3 ubiquitin-protein transferase MAEA OS=Homo sapiens OX=9606 GN=MAEA PE=1 SV=1 5.45 1879.7 - 211445 - - - -2.2656 - 2.015 0.405 - 121.7 1 2 0 -0.004 15 0 0 0 4.49E+06 2.68E+06 - - - 4.8824 0.9979 221125_WJC_METTL3_EV_vs_WT_F10.08229.08229.3 0.000223 Aug-76 R.R[166.11]TPAPPEPGSPAPGEGPSGR[166.11].K sp|P0C1Z6|TFPT_HUMAN 1 1932.9557 1.45 140870 8229 3 1932.963337 645.3258 TCF3 fusion partner OS=Homo sapiens OX=9606 GN=TFPT PE=1 SV=1 6.14 1879.8 - 120874 - - - 3.9623 - 1.766 0.394 - 47.7 1 2 0 0.0077 20 0 0 0 3.24E+06 2.23E+06 - - - 4.3103 1 221125_WJC_METTL3_EV_vs_WT_F10.08234.08234.3 0.0018 18/52 K.SINQQSGAHVELQR[166.11].N sp|Q96I24|FUBP3_HUMAN 1 1575.7993 2.12 140873 8234 3 1575.798669 526.2737 Far upstream element-binding protein 3 OS=Homo sapiens OX=9606 GN=FUBP3 PE=1 SV=2 6.47 1880.5 - 974206 - - - -0.3922 - 3.262 0.464 - 365.3 1 2 0 -0.0006 14 0 0 0 4.35E+07 2.05E+07 - - - 6.8551 0.9599 221125_WJC_METTL3_EV_vs_WT_F10.08247.08247.3 0.0775 Jul-64 K.AVPK[136.11]EDIYSGGGGGGSR[166.11].S sp|Q13151|ROA0_HUMAN 1 1623.7972 37.99 140884 8247 3 1623.795553 542.273 Heterogeneous nuclear ribonucleoprotein A0 OS=Homo sapiens OX=9606 GN=HNRNPA0 PE=1 SV=1 6.11 1882.2 - 181908 - - - -0.9946 - 1.46 0.213 - 39.5 1 2 1 -0.0016 17 0 0 0 9.51E+07 2.50E+06 - - - 1.8703 0.995 221125_WJC_METTL3_EV_vs_WT_F10.08255.08255.3 0.00376 Jun-72 K.ETPENLSNGTSSNVEAAKR.L "sp|Q9NYI0|PSD3_HUMAN,tr|H0YC20|H0YC20_HUMAN,tr|E5RFG7|E5RFG7_HUMAN,tr|E5RJ29|E5RJ29_HUMAN,tr|H0YAQ7|H0YAQ7_HUMAN,tr|E5RJE4|E5RJE4_HUMAN,tr|E5RH02|E5RH02_HUMAN" 7 2002.9556 0.04 140890 8255 3 2002.962344 668.6591 PH and SEC7 domain-containing protein 3 OS=Homo sapiens OX=9606 GN=PSD3 PE=1 SV=2 4.79 1883.2 - 66876.3 - - - 3.379 - 1.391 0.356 - 29.4 1 2 0 0.0068 19 0 0 0 6.93E+05 1.58E+07 - - - 3.318 0.9998 221125_WJC_METTL3_EV_vs_WT_F10.08257.08257.4 6.26E-08 16/78 K.MK[136.11]ETAENYLGHTAK[136.11].N "sp|P38646|GRP75_HUMAN,tr|H0Y8K0|H0Y8K0_HUMAN,tr|A0A7I2V2S7|A0A7I2V2S7_HUMAN,tr|A0A7I2V2G2|A0A7I2V2G2_HUMAN,tr|A0A7I2V3F7|A0A7I2V3F7_HUMAN,tr|A0A7I2YQB2|A0A7I2YQB2_HUMAN,tr|D6RCD7|D6RCD7_HUMAN" 7 1607.7948 0.42 140891 8257 4 1607.797696 402.956 "Stress-70 protein, mitochondrial OS=Homo sapiens OX=9606 GN=HSPA9 PE=1 SV=2" 6.51 1883.5 - 5.43E+06 - - - 1.7751 - 2.695 0.514 - 213.4 1 2 1 0.0029 14 0 0 0 4.77E+07 1.13E+08 - - - 4.0599 0.9999 221125_WJC_METTL3_EV_vs_WT_F10.08260.08260.3 8.16E-05 13/36 R.K[136.11]QDSGHLDLR[166.11].N "sp|Q86U44|MTA70_HUMAN,tr|B4E349|B4E349_HUMAN,tr|F5H6D8|F5H6D8_HUMAN,tr|B4DTN4|B4DTN4_HUMAN" 4 1185.6221 0.57 140893 8260 3 1185.626457 396.2146 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 6.75 1883.8 - 546265 - - - 3.6706 - 2.496 0.525 - 255.7 1 2 0 0.0044 10 0 0 0 6.44E+06 1.13E+07 - - - 7.0633 0.9997 221125_WJC_METTL3_EV_vs_WT_F10.08266.08266.4 1.39E-05 16/78 K.MKETAENYLGHTAK.N "sp|P38646|GRP75_HUMAN,tr|H0Y8K0|H0Y8K0_HUMAN,tr|A0A7I2V2S7|A0A7I2V2S7_HUMAN,tr|A0A7I2V2G2|A0A7I2V2G2_HUMAN,tr|A0A7I2V3F7|A0A7I2V3F7_HUMAN,tr|A0A7I2YQB2|A0A7I2YQB2_HUMAN,tr|D6RCD7|D6RCD7_HUMAN" 7 1591.7664 0.28 140898 8266 4 1591.769342 398.9489 "Stress-70 protein, mitochondrial OS=Homo sapiens OX=9606 GN=HSPA9 PE=1 SV=2" 6.51 1884.6 - 1.87E+06 - - - 1.8219 - 2.706 0.467 - 206.6 1 2 1 0.0029 14 0 0 0 4.97E+07 1.80E+08 - - - 3.6523 0.9999 221125_WJC_METTL3_EV_vs_WT_F10.08268.08268.3 2.91E-09 15/52 R.GGNR[166.11]FEPYANPTK[136.11]R[166.11].Y "sp|P52272|HNRPM_HUMAN,tr|M0R019|M0R019_HUMAN,tr|M0R0Y6|M0R0Y6_HUMAN,tr|M0R0N3|M0R0N3_HUMAN,tr|A0A087X0X3|A0A087X0X3_HUMAN,tr|M0QYQ7|M0QYQ7_HUMAN,tr|M0R2T0|M0R2T0_HUMAN" 7 1633.8319 2.73 140899 8268 3 1633.834497 545.6179 Heterogeneous nuclear ribonucleoprotein M OS=Homo sapiens OX=9606 GN=HNRNPM PE=1 SV=3 9.99 1884.8 - 353570 - - - 1.5724 - 2.616 0.565 - 296.8 1 2 1 0.0026 14 0 0 0 2.49E+08 9.10E+07 - - - 7.3941 0.9934 221125_WJC_METTL3_EV_vs_WT_F10.08277.08277.4 3.92E-07 15/132 A.YDPEAASAPGSGNPC[160.03]HEASAAQK.E sp|P81605|DCD_HUMAN 1 2313.992 999 140906 8277 4 2313.997787 579.5053 Dermcidin OS=Homo sapiens OX=9606 GN=DCD PE=1 SV=2 4.65 1885.9 - 312818 - - - 2.4845 - 2.473 0.536 - 146.1 1 1 0 0.0057 23 0 0 0 1.38E+07 0.00E+00 - - - 4.1831 0.9924 221125_WJC_METTL3_EV_vs_WT_F10.08281.08281.3 0.000246 Oct-68 K.ELAQIAGRPTEDEDEKEK.V sp|O15355|PPM1G_HUMAN 1 2056.9913 0.09 140910 8281 3 2056.997867 686.671 Protein phosphatase 1G OS=Homo sapiens OX=9606 GN=PPM1G PE=1 SV=1 4.25 1886.4 - 113838 - - - 3.1959 - 1.789 0.364 - 120.6 1 2 1 0.0066 18 0 0 0 2.04E+06 2.30E+07 - - - 4.0448 1 221125_WJC_METTL3_EV_vs_WT_F10.08284.08284.3 9.83E-08 18/48 R.SKVEETTEHLVTK.S "sp|P52732|KIF11_HUMAN,tr|A0A7I2V3A9|A0A7I2V3A9_HUMAN" 2 1499.7831 4.38 140912 8284 3 1499.786064 500.935 Kinesin-like protein KIF11 OS=Homo sapiens OX=9606 GN=KIF11 PE=1 SV=2 5.47 1886.8 - 1.75E+06 - - - 1.9509 - 3.526 0.588 - 261.5 1 2 1 0.0029 13 0 0 0 3.68E+09 8.39E+08 - - - 8.5115 0.9961 221125_WJC_METTL3_EV_vs_WT_F10.08287.08287.3 0.255 Aug-56 R.VHTGQR[166.11]PFSC[160.03]GIC[160.03]GK[136.11].S "sp|Q9H5H4|ZN768_HUMAN,tr|H3BS42|H3BS42_HUMAN" 2 1720.8256 1.2 140914 8287 3 1720.830085 574.6158 Zinc finger protein 768 OS=Homo sapiens OX=9606 GN=ZNF768 PE=1 SV=2 8.95 1887.1 - 171424 - - - 2.5778 - 1.673 0.287 - 48.9 1 2 0 0.0044 15 0 0 0 4.83E+06 4.04E+06 - - - 3.0814 1 221125_WJC_METTL3_EV_vs_WT_F10.08288.08288.4 6.98E-05 14/78 K.NPSDSAVHSPFTK[136.11]R[166.11].Q "sp|Q14157|UBP2L_HUMAN,tr|F8W726|F8W726_HUMAN" 2 1559.7811 2.17 140915 8288 4 1559.781492 390.9526 Ubiquitin-associated protein 2-like OS=Homo sapiens OX=9606 GN=UBAP2L PE=1 SV=2 8.75 1887.3 - 444643 - - - 0.2359 - 2.073 0.513 - 153.3 1 2 0 0.0004 14 0 0 0 4.42E+07 2.04E+07 - - - 3.9564 0.9983 221125_WJC_METTL3_EV_vs_WT_F10.08290.08290.3 0.171 Dec-72 R.RPLRPQVVTDDDGQAPEAK.D sp|Q9HDC9|APMAP_HUMAN 1 2091.0709 1.11 140917 8290 3 2091.074925 698.0309 Adipocyte plasma membrane-associated protein OS=Homo sapiens OX=9606 GN=APMAP PE=1 SV=2 4.68 1887.5 - 132947 - - - 1.9339 - 1.901 0.291 - 98.8 1 2 0 0.004 19 0 0 0 1.51E+07 1.36E+07 - - - 3.3614 0.9929 221125_WJC_METTL3_EV_vs_WT_F10.08295.08295.3 0.177 Jun-56 R.VHTGQRPFSC[160.03]GIC[160.03]GK.S "sp|Q9H5H4|ZN768_HUMAN,tr|H3BS42|H3BS42_HUMAN" 2 1702.8032 1.2 140920 8295 3 1702.806308 568.6083 Zinc finger protein 768 OS=Homo sapiens OX=9606 GN=ZNF768 PE=1 SV=2 8.95 1888.1 - 219925 - - - 1.8376 - 1.321 0.278 - 49.9 1 2 0 0.0031 15 0 0 0 4.83E+06 4.04E+06 - - - 2.365 0.9992 221125_WJC_METTL3_EV_vs_WT_F10.08297.08297.3 9.77E-05 14/44 R.K[136.11]R[166.11]EDEAPILEQR[166.11].E "sp|Q14202|ZMYM3_HUMAN,tr|A6NHB5|A6NHB5_HUMAN,tr|A6NHN7|A6NHN7_HUMAN" 3 1510.8098 0.76 140921 8297 3 1510.813877 504.6105 Zinc finger MYM-type protein 3 OS=Homo sapiens OX=9606 GN=ZMYM3 PE=1 SV=2 4.87 1888.4 - 259542 - - - 2.7012 - 2.571 0.418 - 365.2 1 2 1 0.0041 12 0 0 0 4.67E+06 6.11E+06 - - - 5.8166 1 221125_WJC_METTL3_EV_vs_WT_F10.08300.08300.2 4.28E-09 16/44 A.YDPEAASAPGSGNPC[160.03]HEASAAQK.E sp|P81605|DCD_HUMAN 1 2313.992 999 140924 8300 2 2313.991958 1158.0033 Dermcidin OS=Homo sapiens OX=9606 GN=DCD PE=1 SV=2 4.65 1888.7 - 143524 - - - -0.0346 - 2.964 0.638 - 324.7 1 1 0 -0.0001 23 0 0 0 5.41E+06 0.00E+00 - - - 6.4246 0.9995 221125_WJC_METTL3_EV_vs_WT_F10.08304.08304.4 1.66E-07 17/78 R.GGNRFEPYANPTKR.Y "sp|P52272|HNRPM_HUMAN,tr|M0R019|M0R019_HUMAN,tr|M0R0Y6|M0R0Y6_HUMAN,tr|M0R0N3|M0R0N3_HUMAN,tr|A0A087X0X3|A0A087X0X3_HUMAN,tr|M0QYQ7|M0QYQ7_HUMAN,tr|M0R2T0|M0R2T0_HUMAN" 7 1605.8012 1.72 140926 8304 4 1605.801852 402.4576 Heterogeneous nuclear ribonucleoprotein M OS=Homo sapiens OX=9606 GN=HNRNPM PE=1 SV=3 9.99 1889.3 - 3.83E+06 - - - 0.4135 - 3.013 0.391 - 341.4 1 2 1 0.0007 14 0 0 0 1.94E+08 1.12E+08 - - - 3.0305 0.9999 221125_WJC_METTL3_EV_vs_WT_F10.08306.08306.4 0.00113 15/108 R.RPLRPQVVTDDDGQAPEAK.D sp|Q9HDC9|APMAP_HUMAN 1 2091.0709 0.81 140928 8306 4 2091.07297 523.775 Adipocyte plasma membrane-associated protein OS=Homo sapiens OX=9606 GN=APMAP PE=1 SV=2 4.68 1889.6 - 466309 - - - 0.999 - 2.645 0.421 - 151.1 1 2 0 0.0021 19 0 0 0 1.74E+07 2.14E+07 - - - 3.2188 0.9999 221125_WJC_METTL3_EV_vs_WT_F10.08311.08311.4 2.41E-08 18/78 R.GGNR[166.11]FEPYANPTK[136.11]R[166.11].Y "sp|P52272|HNRPM_HUMAN,tr|M0R019|M0R019_HUMAN,tr|M0R0Y6|M0R0Y6_HUMAN,tr|M0R0N3|M0R0N3_HUMAN,tr|A0A087X0X3|A0A087X0X3_HUMAN,tr|M0QYQ7|M0QYQ7_HUMAN,tr|M0R2T0|M0R2T0_HUMAN" 7 1633.8319 2.09 140931 8311 4 1633.831709 409.4653 Heterogeneous nuclear ribonucleoprotein M OS=Homo sapiens OX=9606 GN=HNRNPM PE=1 SV=3 9.99 1890.2 - 3.15E+06 - - - -0.134 - 2.599 0.566 - 228.8 1 2 1 -0.0002 14 0 0 0 2.41E+08 1.16E+08 - - - 4.5 1 221125_WJC_METTL3_EV_vs_WT_F10.08312.08312.3 3.84E-06 15/52 K.NPSDSAVHSPFTK[136.11]R[166.11].Q "sp|Q14157|UBP2L_HUMAN,tr|F8W726|F8W726_HUMAN" 2 1559.7811 1.94 140932 8312 3 1559.781904 520.9343 Ubiquitin-associated protein 2-like OS=Homo sapiens OX=9606 GN=UBAP2L PE=1 SV=2 8.75 1890.3 - 612797 - - - 0.5001 - 2.724 0.502 - 374.1 1 2 0 0.0008 14 0 0 0 4.24E+07 2.18E+07 - - - 6.7997 0.9999 221125_WJC_METTL3_EV_vs_WT_F10.08313.08313.3 0.000297 15/72 R.R[166.11]PLR[166.11]PQVVTDDDGQAPEAK[136.11].D sp|Q9HDC9|APMAP_HUMAN 1 2119.1016 1.24 140933 8313 3 2119.102066 707.3745 Adipocyte plasma membrane-associated protein OS=Homo sapiens OX=9606 GN=APMAP PE=1 SV=2 4.68 1890.5 - 385166 - - - 0.21 - 2.773 0.416 - 159.4 1 2 0 0.0004 19 0 0 0 1.51E+07 1.21E+07 - - - 5.6836 0.9314 221125_WJC_METTL3_EV_vs_WT_F10.08317.08317.4 0.14 9/102 R.TPESSHEGLITDPHSPSR.F "sp|P42892|ECE1_HUMAN,tr|B4DKB2|B4DKB2_HUMAN,tr|A0A3B3ISF9|A0A3B3ISF9_HUMAN" 3 1945.913 2.06 140937 8317 4 1945.91413 487.4855 Endothelin-converting enzyme 1 OS=Homo sapiens OX=9606 GN=ECE1 PE=1 SV=2 5.26 1891 - 161926 - - - 0.5894 - 1.62 0.129 - 46.2 1 2 0 0.0011 18 0 0 0 3.14E+06 1.53E+06 - - - 0.5138 1 221125_WJC_METTL3_EV_vs_WT_F10.08319.08319.3 2.57E-09 24/52 R.GGNRFEPYANPTKR.Y "sp|P52272|HNRPM_HUMAN,tr|M0R019|M0R019_HUMAN,tr|M0R0Y6|M0R0Y6_HUMAN,tr|M0R0N3|M0R0N3_HUMAN,tr|A0A087X0X3|A0A087X0X3_HUMAN,tr|M0QYQ7|M0QYQ7_HUMAN,tr|M0R2T0|M0R2T0_HUMAN" 7 1605.8012 1.78 140938 8319 3 1605.802358 536.2743 Heterogeneous nuclear ribonucleoprotein M OS=Homo sapiens OX=9606 GN=HNRNPM PE=1 SV=3 9.99 1891.3 - 4.83E+06 - - - 0.7286 - 3.736 0.598 - 1066.3 1 2 1 0.0012 14 0 0 0 1.53E+08 8.63E+07 - - - 8.7095 0.9999 221125_WJC_METTL3_EV_vs_WT_F10.08324.08324.3 2.35E-06 14/44 K.QR[166.11]YPDGIISK[136.11]PK[136.11].N sp|Q86U44|MTA70_HUMAN 1 1426.8143 0 140940 8324 3 1426.813046 476.612 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 9.7 1891.9 - 3.02E+06 - - - -0.8572 - 2.256 0.55 - 302.4 1 2 1 -0.0012 12 0 0 0 1.79E+07 1.45E+10 - - - 6.9268 0.9966 221125_WJC_METTL3_EV_vs_WT_F10.08326.08326.3 1.79E-05 Dec-40 S.DTWSSIQAHK[136.11]K[136.11].Q "sp|Q86U44|MTA70_HUMAN,tr|B4E349|B4E349_HUMAN,tr|F5H6D8|F5H6D8_HUMAN,tr|B4DTN4|B4DTN4_HUMAN" 4 1315.6855 0.14 140942 8326 3 1315.685479 439.5691 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 8.6 1892.2 - 438724 - - - -0.0532 - 2.127 0.514 - 206.8 1 1 0 -0.0001 11 0 0 0 9.43E+05 6.58E+06 - - - 6.4146 0.9998 221125_WJC_METTL3_EV_vs_WT_F10.08327.08327.3 1.41E-05 13/44 K.NK[136.11]EHEIEVIDQR[166.11].L sp|Q9ULM3|YETS2_HUMAN 1 1526.7808 0.82 140943 8327 3 1526.781569 509.9342 YEATS domain-containing protein 2 OS=Homo sapiens OX=9606 GN=YEATS2 PE=1 SV=2 4.83 1892.3 - 349015 - - - 0.5102 - 2.527 0.468 - 263.8 1 2 1 0.0008 12 0 0 0 2.81E+06 3.44E+06 - - - 6.3271 1 221125_WJC_METTL3_EV_vs_WT_F10.08331.08331.3 4.98E-07 Dec-72 K.K[136.11]VAQPPLSAQATGSGQPTR[166.11].K "sp|Q86UK7|ZN598_HUMAN,tr|H3BR87|H3BR87_HUMAN,tr|H3BQQ2|H3BQQ2_HUMAN,tr|H3BPG6|H3BPG6_HUMAN" 4 1911.0293 0.4 140946 8331 3 1911.030696 638.017 E3 ubiquitin-protein ligase ZNF598 OS=Homo sapiens OX=9606 GN=ZNF598 PE=1 SV=1 11 1892.8 - 260281 - - - 0.7336 - 2.527 0.55 - 160.5 1 2 0 0.0014 19 0 0 0 4.20E+06 1.05E+07 - - - 6.9491 1 221125_WJC_METTL3_EV_vs_WT_F10.08334.08334.4 9.07E-07 20/108 R.R[166.11]PLR[166.11]PQVVTDDDGQAPEAK[136.11].D sp|Q9HDC9|APMAP_HUMAN 1 2119.1016 1.19 140948 8334 4 2119.102144 530.7827 Adipocyte plasma membrane-associated protein OS=Homo sapiens OX=9606 GN=APMAP PE=1 SV=2 4.68 1893.1 - 670376 - - - 0.2468 - 3.347 0.532 - 340.4 1 2 0 0.0005 19 0 0 0 1.64E+07 1.38E+07 - - - 4.265 0.8405 221125_WJC_METTL3_EV_vs_WT_F10.08336.08336.3 0.572 Sep-44 K.NKEHEIEVIDQR.L sp|Q9ULM3|YETS2_HUMAN 1 1508.7583 0.82 140950 8336 3 1508.756533 503.9267 YEATS domain-containing protein 2 OS=Homo sapiens OX=9606 GN=YEATS2 PE=1 SV=2 4.83 1893.4 - 174664 - - - -1.1844 - 1.565 0.113 - 122.4 1 2 1 -0.0018 12 0 0 0 2.81E+06 3.44E+06 - - - 1.0408 0.9968 221125_WJC_METTL3_EV_vs_WT_F10.08341.08341.3 0.00295 Aug-52 R.DQGGFGDR[166.11]NEYGSR[166.11].L "sp|Q92945|FUBP2_HUMAN,tr|M0R0I5|M0R0I5_HUMAN,tr|M0R0C6|M0R0C6_HUMAN,tr|A0A087WTP3|A0A087WTP3_HUMAN" 4 1576.6769 2.08 140953 8341 3 1576.672016 526.5663 Far upstream element-binding protein 2 OS=Homo sapiens OX=9606 GN=KHSRP PE=1 SV=4 4.56 1894 - 216219 - - - -3.1211 - 1.753 0.42 - 59.1 1 2 1 -0.0049 14 0 0 0 5.78E+06 2.77E+06 - - - 4.713 0.9995 221125_WJC_METTL3_EV_vs_WT_F10.08347.08347.3 0.0027 Dec-44 R.QSVENDIHGLR[166.11]K[136.11].V "sp|P05783|K1C18_HUMAN,tr|F8VZY9|F8VZY9_HUMAN" 2 1412.7491 2.21 140956 8347 3 1412.749358 471.9236 "Keratin, type I cytoskeletal 18 OS=Homo sapiens OX=9606 GN=KRT18 PE=1 SV=2" 6.75 1894.8 - 1.15E+06 - - - 0.1855 - 1.794 0.326 - 204.1 1 2 0 0.0003 12 0 0 0 7.23E+07 3.28E+07 - - - 3.7945 0.9998 221125_WJC_METTL3_EV_vs_WT_F10.08358.08358.3 4.22E-06 Dec-60 K.HPSVGDNKPVELQPER.S "sp|Q03112|MECOM_HUMAN,tr|E7EUL6|E7EUL6_HUMAN,tr|A0A0C3SFZ7|A0A0C3SFZ7_HUMAN" 3 1800.9119 2.05 140965 8358 3 1800.90666 601.3112 Histone-lysine N-methyltransferase MECOM OS=Homo sapiens OX=9606 GN=MECOM PE=1 SV=3 5.45 1896.3 - 550357 - - - -2.888 - 2.367 0.448 - 132.9 1 2 0 -0.0052 16 0 0 0 1.44E+07 7.04E+06 - - - 5.7441 0.9821 221125_WJC_METTL3_EV_vs_WT_F10.08360.08360.2 0.0674 14-Jul P.DGIISK[136.11]PK[136.11].N sp|Q86U44|MTA70_HUMAN 1 872.5302 0 140967 8360 2 872.52981 437.2724 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 8.59 1896.4 - 526935 - - - -0.4676 - 1.751 0.387 - 144.8 1 1 0 -0.0004 8 0 0 0 4.28E+04 1.97E+08 - - - 3.5888 0.9998 221125_WJC_METTL3_EV_vs_WT_F10.08361.08361.3 0.000399 16/52 R.FR[166.11]PLNESEVNR[166.11]GDK[136.11].Y sp|P33176|KINH_HUMAN 1 1687.8636 1.85 140968 8361 3 1687.864579 563.6285 Kinesin-1 heavy chain OS=Homo sapiens OX=9606 GN=KIF5B PE=1 SV=1 6.18 1896.6 - 422767 - - - 0.567 - 2.912 0.398 - 457.6 1 2 1 0.001 14 0 0 0 8.92E+06 4.81E+06 - - - 5.8175 1 221125_WJC_METTL3_EV_vs_WT_F10.08366.08366.3 9.80E-08 16/64 K.SSTTVSSFANSK[136.11]PGSAK[136.11].K "sp|Q13620|CUL4B_HUMAN,tr|A0A669KAX4|A0A669KAX4_HUMAN,tr|A0A7P0T8W4|A0A7P0T8W4_HUMAN,tr|K4DI93|K4DI93_HUMAN,tr|A0A804CL36|A0A804CL36_HUMAN,tr|A0A7P0T954|A0A7P0T954_HUMAN,tr|A0A669KAU9|A0A669KAU9_HUMAN,tr|A0A7P0T9R8|A0A7P0T9R8_HUMAN,tr|A0A7P0T9L3|A0A7P0T9L3_HUMAN,tr|A0A7P0TAQ3|A0A7P0TAQ3_HUMAN" 10 1670.8446 0.62 140971 8366 3 1670.845162 557.9555 Cullin-4B OS=Homo sapiens OX=9606 GN=CUL4B PE=1 SV=4 10 1897.2 - 445248 - - - 0.319 - 3.164 0.563 - 338.9 1 2 0 0.0005 17 0 0 0 1.53E+07 2.46E+07 - - - 7.7266 0.9975 221125_WJC_METTL3_EV_vs_WT_F10.08374.08374.2 0.000887 22-Dec K.QR[166.11]YPDGIISK[136.11]PK[136.11].N sp|Q86U44|MTA70_HUMAN 1 1426.8143 0.001 140977 8374 2 1426.812696 714.4144 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 9.7 1898.2 - 2.94E+06 - - - -1.1025 - 2.491 0.381 - 391.4 1 2 1 -0.0016 12 0 0 0 0.00E+00 6.98E+08 - - - 4.256 0.9999 221125_WJC_METTL3_EV_vs_WT_F10.08377.08377.3 0.000183 18/52 R.FRPLNESEVNRGDK.Y sp|P33176|KINH_HUMAN 1 1659.8329 1.92 140979 8377 3 1659.832381 554.2849 Kinesin-1 heavy chain OS=Homo sapiens OX=9606 GN=KIF5B PE=1 SV=1 6.18 1898.5 - 508069 - - - -0.3018 - 3.232 0.455 - 402.8 1 2 1 -0.0005 14 0 0 0 9.58E+06 4.99E+06 - - - 6.7302 0.9584 221125_WJC_METTL3_EV_vs_WT_F10.08379.08379.3 0.0521 Aug-60 R.QK[136.11]EEESQQQAVLEQER[166.11].R "sp|Q9UM54|MYO6_HUMAN,tr|Q5JVM0|Q5JVM0_HUMAN,tr|A0A0A0MRM8|A0A0A0MRM8_HUMAN,tr|A0A590UJ40|A0A590UJ40_HUMAN,tr|E7EW20|E7EW20_HUMAN,tr|A0A1Y0BRN3|A0A1Y0BRN3_HUMAN" 6 1975.9566 1.35 140981 8379 3 1975.94911 659.6595 Unconventional myosin-VI OS=Homo sapiens OX=9606 GN=MYO6 PE=1 SV=4 4.33 1898.8 - 284470 - - - -3.7815 - 1.838 0.266 - 73.1 1 2 1 -0.0075 16 0 0 0 4.83E+06 3.57E+06 - - - 3.0654 1 221125_WJC_METTL3_EV_vs_WT_F10.08382.08382.3 3.97E-07 15/52 K.NPSDSAVHSPFTKR.Q "sp|Q14157|UBP2L_HUMAN,tr|F8W726|F8W726_HUMAN" 2 1541.7587 0.59 140983 8382 3 1541.757357 514.9268 Ubiquitin-associated protein 2-like OS=Homo sapiens OX=9606 GN=UBAP2L PE=1 SV=2 8.75 1899.1 - 1.35E+06 - - - -0.8412 - 2.962 0.578 - 406.4 1 2 0 -0.0013 14 0 0 0 1.20E+08 2.05E+08 - - - 7.8695 1 221125_WJC_METTL3_EV_vs_WT_F10.08389.08389.3 6.33E-07 19/64 K.SSTTVSSFANSKPGSAK.K "sp|Q13620|CUL4B_HUMAN,tr|A0A669KAX4|A0A669KAX4_HUMAN,tr|A0A7P0T8W4|A0A7P0T8W4_HUMAN,tr|K4DI93|K4DI93_HUMAN,tr|A0A804CL36|A0A804CL36_HUMAN,tr|A0A7P0T954|A0A7P0T954_HUMAN,tr|A0A669KAU9|A0A669KAU9_HUMAN,tr|A0A7P0T9R8|A0A7P0T9R8_HUMAN,tr|A0A7P0T9L3|A0A7P0T9L3_HUMAN,tr|A0A7P0TAQ3|A0A7P0TAQ3_HUMAN" 10 1654.8162 0.62 140988 8389 3 1654.815573 552.6127 Cullin-4B OS=Homo sapiens OX=9606 GN=CUL4B PE=1 SV=4 10 1900 - 796176 - - - -0.3964 - 3.208 0.537 - 548.1 1 2 0 -0.0007 17 0 0 0 1.53E+07 2.46E+07 - - - 7.4716 1 221125_WJC_METTL3_EV_vs_WT_F10.08395.08395.3 8.82E-08 16/84 K.VLSANHGDPSIQTSGSEQTSPK.S "sp|Q9H694|BICC1_HUMAN,tr|A6NGY7|A6NGY7_HUMAN" 2 2239.0717 4.31 140994 8395 3 2239.068472 747.3645 Protein bicaudal C homolog 1 OS=Homo sapiens OX=9606 GN=BICC1 PE=1 SV=2 5.32 1900.7 - 549425 - - - -1.4278 - 2.861 0.603 - 303.2 1 2 0 -0.0032 22 0 0 0 2.04E+07 4.74E+06 - - - 7.7541 0.9854 221125_WJC_METTL3_EV_vs_WT_F10.08398.08398.3 2.94E-05 Dec-40 Q.R[166.11]YPDGIISK[136.11]PK[136.11].N sp|Q86U44|MTA70_HUMAN 1 1298.7557 0 140995 8398 3 1298.751741 433.9258 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 9.7 1901.1 - 860009 - - - -3.0414 - 2.27 0.484 - 252.3 1 1 0 -0.004 11 0 0 0 1.31E+05 5.03E+07 - - - 6.2639 0.9763 221125_WJC_METTL3_EV_vs_WT_F10.08413.08413.2 8.84E-06 16-Nov Y.PDGIISK[136.11]PK[136.11].N sp|Q86U44|MTA70_HUMAN 1 969.583 0 141006 8413 2 969.580527 485.7988 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 9.01 1902.9 - 3.81E+06 - - - -2.532 - 2.349 0.441 - 376.4 1 1 0 -0.0025 9 0 0 0 4.87E+05 1.86E+08 - - - 4.7681 0.9997 221125_WJC_METTL3_EV_vs_WT_F10.08422.08422.2 0.628 18-Sep R.YPDGIISK[136.11]PK[136.11].N sp|Q86U44|MTA70_HUMAN 1 1132.6463 0.001 141010 8422 2 1132.645357 567.3304 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 8.5 1904.1 - 0 - - - -0.8414 - 1.773 0.426 - 250.1 1 2 0 -0.001 10 0 0 0 0.00E+00 1.04E+07 - - - 3.7856 1 221125_WJC_METTL3_EV_vs_WT_F10.08426.08426.3 1.84E-06 22/48 R.RDSLTGSSDLYKR.T "sp|Q14671|PUM1_HUMAN,tr|Q5T1Z8|Q5T1Z8_HUMAN,tr|H0YDK8|H0YDK8_HUMAN,tr|Q5T1Z4|Q5T1Z4_HUMAN,tr|E9PR38|E9PR38_HUMAN" 5 1496.7583 4.27 141013 8426 3 1496.755066 499.9267 Pumilio homolog 1 OS=Homo sapiens OX=9606 GN=PUM1 PE=1 SV=3 8.59 1904.6 - 1.26E+06 - - - -2.174 - 3.706 0.556 - 705.7 1 2 0 -0.0033 13 0 0 0 6.55E+07 1.53E+07 - - - 8.2896 0.9999 221125_WJC_METTL3_EV_vs_WT_F10.08437.08437.3 0.000211 13/56 K.EQIVPKPEEEVAQKK.K "sp|P18621|RL17_HUMAN,tr|J3QLC8|J3QLC8_HUMAN,tr|J3QQT2|J3QQT2_HUMAN,tr|A0A0A0MRF8|A0A0A0MRF8_HUMAN,tr|J3KRX5|J3KRX5_HUMAN,tr|A0A087WXM6|A0A087WXM6_HUMAN,tr|A0A0A6YYL6|A0A0A6YYL6_HUMAN" 7 1750.9465 1.09 141017 8437 3 1750.943081 584.6561 60S ribosomal protein L17 OS=Homo sapiens OX=9606 GN=RPL17 PE=1 SV=3 4.95 1906 - 489847 - - - -1.9612 - 2.428 0.451 - 172.8 1 2 0 -0.0034 15 0 0 0 1.19E+08 1.09E+08 - - - 5.8819 0.9999 221125_WJC_METTL3_EV_vs_WT_F10.08444.08444.3 0.000331 13/56 K.EQIVPK[136.11]PEEEVAQK[136.11]K[136.11].K "sp|P18621|RL17_HUMAN,tr|J3QLC8|J3QLC8_HUMAN,tr|J3QQT2|J3QQT2_HUMAN,tr|A0A0A0MRF8|A0A0A0MRF8_HUMAN,tr|J3KRX5|J3KRX5_HUMAN,tr|A0A087WXM6|A0A087WXM6_HUMAN,tr|A0A0A6YYL6|A0A0A6YYL6_HUMAN" 7 1774.9891 1.09 141021 8444 3 1774.986668 592.6703 60S ribosomal protein L17 OS=Homo sapiens OX=9606 GN=RPL17 PE=1 SV=3 4.95 1906.8 - 889235 - - - -1.3786 - 2.226 0.426 - 172 1 2 0 -0.0024 15 0 0 0 1.19E+08 1.09E+08 - - - 5.3768 1 221125_WJC_METTL3_EV_vs_WT_F10.08445.08445.2 2.94E-12 16/34 K.SSQTSGTNEQSSAIVSAR[166.11].D sp|O60763|USO1_HUMAN 1 1818.8583 0.75 141022 8445 2 1818.85686 910.4364 General vesicular transport factor p115 OS=Homo sapiens OX=9606 GN=USO1 PE=1 SV=2 5.72 1906.9 - 496169 - - - -0.8016 - 3.272 0.667 - 906.1 1 2 0 -0.0015 18 0 0 0 8.89E+06 1.19E+07 - - - 6.8814 0.9622 221125_WJC_METTL3_EV_vs_WT_F10.08447.08447.2 0.029 13/20 V.STR[166.11]PLPSASQK[136.11].A sp|Q8ND56|LS14A_HUMAN 1 1188.6582 1.03 141024 8447 2 1188.655498 595.3364 Protein LSM14 homolog A OS=Homo sapiens OX=9606 GN=LSM14A PE=1 SV=3 11 1907.2 - 504842 - - - -2.2361 - 2.278 0.338 - 423.6 1 1 0 -0.0027 11 0 0 0 2.42E+07 2.35E+07 - - - 3.7638 0.9998 221125_WJC_METTL3_EV_vs_WT_F10.08452.08452.4 1.02E-05 19/84 K.EQIVPK[136.11]PEEEVAQK[136.11]K[136.11].K "sp|P18621|RL17_HUMAN,tr|J3QLC8|J3QLC8_HUMAN,tr|J3QQT2|J3QQT2_HUMAN,tr|A0A0A0MRF8|A0A0A0MRF8_HUMAN,tr|J3KRX5|J3KRX5_HUMAN,tr|A0A087WXM6|A0A087WXM6_HUMAN,tr|A0A0A6YYL6|A0A0A6YYL6_HUMAN" 7 1774.9891 1.03 141027 8452 4 1774.982409 444.7546 60S ribosomal protein L17 OS=Homo sapiens OX=9606 GN=RPL17 PE=1 SV=3 4.95 1907.8 - 1.57E+06 - - - -3.7781 - 2.447 0.494 - 202.4 1 2 0 -0.0067 15 0 0 0 1.29E+08 1.25E+08 - - - 3.8441 0.9225 221125_WJC_METTL3_EV_vs_WT_F10.08481.08481.3 0.145 Sep-36 R.DREEALHQFR.S "sp|O00571|DDX3X_HUMAN,sp|O15523|DDX3Y_HUMAN,tr|A0A2R8YFR4|A0A2R8YFR4_HUMAN,tr|A0A2R8YCW1|A0A2R8YCW1_HUMAN,tr|A0A2R8YDH3|A0A2R8YDH3_HUMAN,tr|A0A2R8YDT5|A0A2R8YDT5_HUMAN,tr|A0A2R8Y645|A0A2R8Y645_HUMAN,tr|A0A2R8YF78|A0A2R8YF78_HUMAN,tr|A0A0D9SFB3|A0A0D9SFB3_HUMAN,tr|A0A2R8YFS5|A0A2R8YFS5_HUMAN,tr|A0A0D9SF53|A0A0D9SF53_HUMAN,tr|A0A087WVZ1|A0A087WVZ1_HUMAN,tr|A0A0J9YVQ7|A0A0J9YVQ7_HUMAN,tr|A0A2R8Y5G6|A0A2R8Y5G6_HUMAN,tr|A0A2R8Y7T2|A0A2R8Y7T2_HUMAN,tr|A0A0D9SG12|A0A0D9SG12_HUMAN,tr|F6S8Q4|F6S8Q4_HUMAN,tr|A0A2U3TZJ9|A0A2U3TZJ9_HUMAN,tr|A0A2R8Y4A4|A0A2R8Y4A4_HUMAN" 19 1299.632 0.97 141045 8481 3 1299.634735 434.2179 ATP-dependent RNA helicase DDX3X OS=Homo sapiens OX=9606 GN=DDX3X PE=1 SV=3 5.45 1911.4 - 787714 - - - 2.1068 - 1.531 0.189 - 121.1 1 2 1 0.0027 10 0 0 0 1.60E+07 1.64E+07 - - - 1.8903 1 221125_WJC_METTL3_EV_vs_WT_F10.08485.08485.4 4.25E-06 19/84 K.EQIVPKPEEEVAQKK.K "sp|P18621|RL17_HUMAN,tr|J3QLC8|J3QLC8_HUMAN,tr|J3QQT2|J3QQT2_HUMAN,tr|A0A0A0MRF8|A0A0A0MRF8_HUMAN,tr|J3KRX5|J3KRX5_HUMAN,tr|A0A087WXM6|A0A087WXM6_HUMAN,tr|A0A0A6YYL6|A0A0A6YYL6_HUMAN" 7 1750.9465 1.03 141046 8485 4 1750.943986 438.7439 60S ribosomal protein L17 OS=Homo sapiens OX=9606 GN=RPL17 PE=1 SV=3 4.95 1912 - 2.24E+06 - - - -1.4444 - 3.123 0.5 - 276.3 1 2 0 -0.0025 15 0 0 0 1.28E+08 1.24E+08 - - - 3.9848 1 221125_WJC_METTL3_EV_vs_WT_F10.08496.08496.3 7.92E-12 21/84 R.GAQDVAGGSNPGAHNPSANLAR.G "sp|O14654|IRS4_HUMAN,tr|A0A804CF45|A0A804CF45_HUMAN" 2 2059.9784 1.37 141051 8496 3 2059.975385 687.6667 Insulin receptor substrate 4 OS=Homo sapiens OX=9606 GN=IRS4 PE=1 SV=1 6.74 1913.4 - 1.09E+06 - - - -1.4524 - 3.712 0.647 - 477.4 1 2 0 -0.003 22 0 0 0 3.89E+08 2.84E+08 - - - 8.8621 1 221125_WJC_METTL3_EV_vs_WT_F10.08503.08503.2 1.04E-11 20/28 K.NQQITHANNTVSNFK[136.11].R "sp|Q92598|HS105_HUMAN,tr|A0A0A0MSM0|A0A0A0MSM0_HUMAN,tr|R4GN69|R4GN69_HUMAN" 3 1722.8529 0.12 141056 8503 2 1722.849756 862.4337 Heat shock protein 105 kDa OS=Homo sapiens OX=9606 GN=HSPH1 PE=1 SV=1 8.76 1914.2 - 700989 - - - -1.8226 - 3.869 0.7 - 1614.4 1 2 0 -0.0031 15 0 0 0 5.66E+06 4.91E+07 - - - 7.5366 1 221125_WJC_METTL3_EV_vs_WT_F10.08509.08509.3 1.58E-10 26/84 R.GAQDVAGGSNPGAHNPSANLAR[166.11].G "sp|O14654|IRS4_HUMAN,tr|A0A804CF45|A0A804CF45_HUMAN" 2 2069.9866 1.37 141058 8509 3 2069.991075 691.0028 Insulin receptor substrate 4 OS=Homo sapiens OX=9606 GN=IRS4 PE=1 SV=1 6.74 1915.1 - 1.63E+06 - - - 2.1391 - 4.106 0.624 - 827.7 1 2 0 0.0044 22 0 0 0 3.88E+08 2.84E+08 - - - 8.8444 0.9971 221125_WJC_METTL3_EV_vs_WT_F10.08515.08515.4 0.0632 Dec-96 R.ASGNYATVISHNPETKK.T "sp|P62917|RL8_HUMAN,tr|G3V1A1|G3V1A1_HUMAN,tr|E9PKZ0|E9PKZ0_HUMAN" 3 1815.9115 0.95 141062 8515 4 1815.90753 454.9852 60S ribosomal protein L8 OS=Homo sapiens OX=9606 GN=RPL8 PE=1 SV=2 8.55 1915.9 - 346216 - - - -2.2005 - 2.358 0.265 - 95.2 1 2 0 -0.004 17 0 0 0 1.32E+07 1.39E+07 - - - 1.8293 0.9999 221125_WJC_METTL3_EV_vs_WT_F10.08523.08523.3 9.22E-06 18/68 R.GTQNIPAGKPSLQTSSAR.M sp|Q86YP4|P66A_HUMAN 1 1811.949 1.37 141068 8523 3 1811.944904 604.9903 Transcriptional repressor p66-alpha OS=Homo sapiens OX=9606 GN=GATAD2A PE=1 SV=1 11 1916.8 - 2.19E+06 - - - -2.2468 - 2.588 0.443 - 260.5 1 2 0 -0.0041 18 0 0 0 1.35E+08 9.87E+07 - - - 5.8457 0.9856 221125_WJC_METTL3_EV_vs_WT_F10.08524.08524.3 0.145 Dec-68 R.GTQNIPAGK[136.11]PSLQTSSAR[166.11].M sp|Q86YP4|P66A_HUMAN 1 1829.9714 1.56 141069 8524 3 1829.962886 610.9978 Transcriptional repressor p66-alpha OS=Homo sapiens OX=9606 GN=GATAD2A PE=1 SV=1 11 1916.9 - 1.61E+06 - - - -4.6771 - 1.952 0.27 - 101.5 1 2 0 -0.0086 18 0 0 0 1.31E+08 8.43E+07 - - - 3.2134 0.9732 221125_WJC_METTL3_EV_vs_WT_F10.08527.08527.3 7.37E-09 29/68 K.C[160.03]PEPC[160.03]PPPKC[160.03]PEPC[160.03]PPPK.C "sp|P22531|SPR2E_HUMAN,sp|P35326|SPR2A_HUMAN,sp|P35325|SPR2B_HUMAN" 3 2142.9359 999 141070 8527 3 2142.935324 715.3192 Small proline-rich protein 2E OS=Homo sapiens OX=9606 GN=SPRR2E PE=2 SV=2 6.12 1917.3 - 910860 - - - -0.2735 - 4.22 1 - 1002.7 1 2 1 -0.0006 18 0 0 0 3.99E+07 0.00E+00 - - - 2.1252 0.9998 221125_WJC_METTL3_EV_vs_WT_F10.08528.08528.3 3.92E-07 13/60 K.TATDEAYKDPSNLQGK.V "sp|Q13813|SPTN1_HUMAN,tr|A0A0D9SF54|A0A0D9SF54_HUMAN,tr|A0A0D9SGF6|A0A0D9SGF6_HUMAN" 3 1736.8217 1.65 141071 8528 3 1736.819072 579.9478 "Spectrin alpha chain, non-erythrocytic 1 OS=Homo sapiens OX=9606 GN=SPTAN1 PE=1 SV=3" 4.56 1917.4 - 531226 - - - -1.5177 - 2.262 0.535 - 160.7 1 2 1 -0.0026 16 0 0 0 1.31E+07 7.92E+06 - - - 6.5984 1 221125_WJC_METTL3_EV_vs_WT_F10.08533.08533.3 0.000145 15/56 K.NQQITHANNTVSNFK[136.11].R "sp|Q92598|HS105_HUMAN,tr|A0A0A0MSM0|A0A0A0MSM0_HUMAN,tr|R4GN69|R4GN69_HUMAN" 3 1722.8529 0.15 141075 8533 3 1722.849898 575.2916 Heat shock protein 105 kDa OS=Homo sapiens OX=9606 GN=HSPH1 PE=1 SV=1 8.76 1918 - 3.28E+07 - - - -1.7401 - 3.413 0.566 - 384.4 1 2 0 -0.003 15 0 0 0 9.07E+07 5.96E+08 - - - 8.0527 0.9862 221125_WJC_METTL3_EV_vs_WT_F10.08536.08536.3 0.284 13/40 P.ELATDPELEK[136.11]K[136.11].L "sp|Q86U44|MTA70_HUMAN,tr|B4E349|B4E349_HUMAN,tr|F5H6D8|F5H6D8_HUMAN,tr|H0YFV6|H0YFV6_HUMAN,tr|B4DTN4|B4DTN4_HUMAN" 5 1287.6893 0.01 141077 8536 3 1287.68587 430.237 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 4.41 1918.3 - 658014 - - - -2.6614 - 2.21 0.468 - 310.2 1 1 0 -0.0034 11 0 0 0 6.82E+05 6.93E+07 - - - 6.0095 1 221125_WJC_METTL3_EV_vs_WT_F10.08546.08546.2 1.91E-08 28-Oct K.NQQITHANNTVSNFK.R "sp|Q92598|HS105_HUMAN,tr|A0A0A0MSM0|A0A0A0MSM0_HUMAN,tr|R4GN69|R4GN69_HUMAN" 3 1714.8387 0.12 141085 8546 2 1714.836091 858.4266 Heat shock protein 105 kDa OS=Homo sapiens OX=9606 GN=HSPH1 PE=1 SV=1 8.76 1919.6 - 289192 - - - -1.5191 - 2.426 0.627 - 315.4 1 2 0 -0.0026 15 0 0 0 5.66E+06 4.91E+07 - - - 5.8501 1 221125_WJC_METTL3_EV_vs_WT_F10.08557.08557.4 3.51E-06 14/78 K.YELISETGGSHDK[136.11]R[166.11].F "sp|Q12906|ILF3_HUMAN,sp|Q96SI9|STRBP_HUMAN" 2 1608.7863 1.09 141092 8557 4 1608.785236 403.2038 Interleukin enhancer-binding factor 3 OS=Homo sapiens OX=9606 GN=ILF3 PE=1 SV=3 5.45 1921 - 2.98E+06 - - - -0.6421 - 2.978 0.492 - 210.5 1 2 0 -0.001 14 0 0 0 1.06E+08 9.77E+07 - - - 3.9052 1 221125_WJC_METTL3_EV_vs_WT_F10.08558.08558.3 1.21E-11 23/52 K.SGGASHSELIHNLR.K "sp|P22061|PIMT_HUMAN,tr|F6S8N6|F6S8N6_HUMAN,tr|A0A3F2YNX8|A0A3F2YNX8_HUMAN,tr|F8WAV5|F8WAV5_HUMAN,tr|A0A0A0MRJ6|A0A0A0MRJ6_HUMAN,tr|H7C4X2|H7C4X2_HUMAN,tr|F8WDT3|F8WDT3_HUMAN,tr|F8WAX2|F8WAX2_HUMAN" 8 1476.7433 1.36 141093 8558 3 1476.743276 493.2551 Protein-L-isoaspartate(D-aspartate) O-methyltransferase OS=Homo sapiens OX=9606 GN=PCMT1 PE=1 SV=4 6.66 1921.1 - 1.33E+06 - - - -0.0427 - 4.158 0.704 - 990.7 1 2 0 -0.0001 14 0 0 0 7.93E+07 5.84E+07 - - - 10.176 1 221125_WJC_METTL3_EV_vs_WT_F10.08562.08562.4 4.88E-07 13/78 K.YELISETGGSHDKR.F "sp|Q12906|ILF3_HUMAN,sp|Q96SI9|STRBP_HUMAN" 2 1590.7638 1.08 141095 8562 4 1590.763529 398.6982 Interleukin enhancer-binding factor 3 OS=Homo sapiens OX=9606 GN=ILF3 PE=1 SV=3 5.45 1921.6 - 4.27E+06 - - - -0.1697 - 2.889 0.531 - 176.2 1 2 0 -0.0003 14 0 0 0 1.07E+08 9.88E+07 - - - 4.2339 0.9553 221125_WJC_METTL3_EV_vs_WT_F10.08565.08565.2 0.00126 20-Oct P.ELATDPELEK[136.11]K[136.11].L "sp|Q86U44|MTA70_HUMAN,tr|B4E349|B4E349_HUMAN,tr|F5H6D8|F5H6D8_HUMAN,tr|H0YFV6|H0YFV6_HUMAN,tr|B4DTN4|B4DTN4_HUMAN" 5 1287.6893 0.001 141098 8565 2 1287.685798 644.8519 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 4.41 1922 - 644584 - - - -2.7173 - 2.081 0.402 - 354.5 1 1 0 -0.0035 11 0 0 0 0.00E+00 1.02E+07 - - - 3.9916 1 221125_WJC_METTL3_EV_vs_WT_F10.08571.08571.3 8.41E-08 15/68 K.K[136.11]IEESETIEDSSNQAAAR[166.11].E "sp|Q8N573|OXR1_HUMAN,tr|H0YC07|H0YC07_HUMAN" 2 1994.9512 1.14 141102 8571 3 1994.953563 665.991 Oxidation resistance protein 1 OS=Homo sapiens OX=9606 GN=OXR1 PE=1 SV=2 4.25 1922.8 - 654744 - - - 1.203 - 3.519 0.607 - 366.8 1 2 0 0.0024 18 0 0 0 1.98E+07 1.73E+07 - - - 8.4398 0.9997 221125_WJC_METTL3_EV_vs_WT_F10.08580.08580.3 0.000894 Aug-84 K.LSTSQDAAC[160.03]K[136.11]DAEEC[160.03]PETAEAK[136.11].C "sp|Q5H9R7|PP6R3_HUMAN,tr|H7BXH2|H7BXH2_HUMAN,tr|E9PQP7|E9PQP7_HUMAN,tr|H0YEN2|H0YEN2_HUMAN,tr|E9PKF6|E9PKF6_HUMAN" 5 2426.0548 5.33 141109 8580 3 2426.054253 809.6922 Serine\threonine-protein phosphatase 6 regulatory subunit 3 OS=Homo sapiens OX=9606 GN=PPP6R3 PE=1 SV=2 4.08 1923.9 - 207576 - - - -0.2399 - 1.618 0.529 - 48 1 2 1 -0.0006 22 0 0 0 5.36E+07 1.00E+07 - - - 5.5785 0.9887 221125_WJC_METTL3_EV_vs_WT_F10.08586.08586.3 5.65E-05 Dec-64 K.QTAISQPASGNTFSHHS.M "sp|Q14157|UBP2L_HUMAN,tr|F8W726|F8W726_HUMAN,tr|Q5VU77|Q5VU77_HUMAN" 3 1768.8129 - 141113 8586 3 1768.812931 590.6116 Ubiquitin-associated protein 2-like OS=Homo sapiens OX=9606 GN=UBAP2L PE=1 SV=2 6.92 1924.7 - 451578 - - - 0.0317 - 2.481 0.384 - 160.9 1 1 0 0.0001 17 0 0 0 - - - - - 5.1168 1 221125_WJC_METTL3_EV_vs_WT_F10.08587.08587.3 1.83E-07 18/52 K.YELISETGGSHDK[136.11]R[166.11].F "sp|Q12906|ILF3_HUMAN,sp|Q96SI9|STRBP_HUMAN" 2 1608.7863 1.06 141114 8587 3 1608.785818 537.2694 Interleukin enhancer-binding factor 3 OS=Homo sapiens OX=9606 GN=ILF3 PE=1 SV=3 5.45 1924.7 - 6.66E+06 - - - -0.2803 - 3.65 0.595 - 455.6 1 2 0 -0.0005 14 0 0 0 1.22E+08 1.15E+08 - - - 8.6143 0.9995 221125_WJC_METTL3_EV_vs_WT_F10.08591.08591.2 0.0132 26-Aug K.YELISETGGSHDKR.F "sp|Q12906|ILF3_HUMAN,sp|Q96SI9|STRBP_HUMAN" 2 1590.7638 1.19 141118 8591 2 1590.762914 796.3892 Interleukin enhancer-binding factor 3 OS=Homo sapiens OX=9606 GN=ILF3 PE=1 SV=3 5.45 1925.2 - 213051 - - - -0.5563 - 1.974 0.321 - 187.9 1 2 0 -0.0009 14 0 0 0 3.43E+06 2.88E+06 - - - 3.1182 1 221125_WJC_METTL3_EV_vs_WT_F10.08595.08595.3 5.84E-06 17/52 K.YELISETGGSHDKR.F "sp|Q12906|ILF3_HUMAN,sp|Q96SI9|STRBP_HUMAN" 2 1590.7638 1.05 141120 8595 3 1590.763514 531.2619 Interleukin enhancer-binding factor 3 OS=Homo sapiens OX=9606 GN=ILF3 PE=1 SV=3 5.45 1925.8 - 7.75E+06 - - - -0.1792 - 3.205 0.568 - 388.3 1 2 0 -0.0003 14 0 0 0 1.22E+08 1.16E+08 - - - 7.9678 1 221125_WJC_METTL3_EV_vs_WT_F10.08596.08596.3 4.99E-06 15/40 K.KDEIENSIVHR.V sp|Q9NYH9|UTP6_HUMAN 1 1338.6892 1.31 141121 8596 3 1338.688789 447.237 U3 small nucleolar RNA-associated protein 6 homolog OS=Homo sapiens OX=9606 GN=UTP6 PE=1 SV=2 5.45 1925.9 - 625112 - - - -0.2906 - 2.687 0.518 - 429.8 1 2 0 -0.0004 11 0 0 0 1.37E+07 1.04E+07 - - - 7.123 0.998 221125_WJC_METTL3_EV_vs_WT_F10.08600.08600.4 0.000516 Nov-90 K.SIIKEDIHPAPSTNSK.D tr|A0A1B0GTZ1|A0A1B0GTZ1_HUMAN 1 1735.9105 0.06 141125 8600 4 1735.910135 434.9849 Synaptotagmin-14 OS=Homo sapiens OX=9606 GN=SYT14 PE=4 SV=1 6.47 1926.4 - 230224 - - - -0.1895 - 2.116 0.329 - 69.2 1 2 1 -0.0003 16 0 0 0 2.23E+06 3.89E+07 - - - 2.3536 0.9995 221125_WJC_METTL3_EV_vs_WT_F10.08601.08601.3 2.22E-06 14/60 K.SIIKEDIHPAPSTNSK.D tr|A0A1B0GTZ1|A0A1B0GTZ1_HUMAN 1 1735.9105 0.08 141126 8601 3 1735.912421 579.6441 Synaptotagmin-14 OS=Homo sapiens OX=9606 GN=SYT14 PE=4 SV=1 6.47 1926.6 - 221650 - - - 1.1274 - 2.499 0.396 - 214.6 1 2 1 0.002 16 0 0 0 2.66E+06 3.28E+07 - - - 5.3045 1 221125_WJC_METTL3_EV_vs_WT_F10.08602.08602.2 2.10E-09 Sep-42 R.GAQDVAGGSNPGAHNPSANLAR.G "sp|O14654|IRS4_HUMAN,tr|A0A804CF45|A0A804CF45_HUMAN" 2 2059.9784 1.81 141127 8602 2 2059.981827 1030.9965 Insulin receptor substrate 4 OS=Homo sapiens OX=9606 GN=IRS4 PE=1 SV=1 6.74 1926.7 - 89418.5 - - - 1.6748 - 2.164 0.662 - 161.7 1 2 0 0.0034 22 0 0 0 2.98E+06 1.64E+06 - - - 5.8273 0.9993 221125_WJC_METTL3_EV_vs_WT_F10.08603.08603.3 0.00135 Jul-76 K.AQPAQPADEPAEK[136.11]ADEPMEH.- "sp|P25786|PSA1_HUMAN,tr|F5GX11|F5GX11_HUMAN" 2 2167.9572 0.78 141128 8603 3 2167.9572 723.6597 Proteasome subunit alpha type-1 OS=Homo sapiens OX=9606 GN=PSMA1 PE=1 SV=1 4.08 1926.8 - 0 - - - 0.0171 - 1.697 0.443 - 56.7 1 2 1 0 20 0 0 0 5.79E+06 7.44E+06 - - - 4.762 1 221125_WJC_METTL3_EV_vs_WT_F10.08607.08607.3 1.23E-08 14/68 R.SR[166.11]EDAGDNDDTEGAIGVR[166.11].N sp|Q9H0S4|DDX47_HUMAN 1 1895.836 1.14 141131 8607 3 1895.839476 632.9526 Probable ATP-dependent RNA helicase DDX47 OS=Homo sapiens OX=9606 GN=DDX47 PE=1 SV=1 3.96 1927.3 - 227144 - - - 1.8245 - 2.981 0.7 - 227.9 1 2 1 0.0035 18 0 0 0 1.30E+07 1.14E+07 - - - 9.0632 0.9992 221125_WJC_METTL3_EV_vs_WT_F10.08618.08618.2 0.000431 26-Aug K.YELISETGGSHDK[136.11]R[166.11].F "sp|Q12906|ILF3_HUMAN,sp|Q96SI9|STRBP_HUMAN" 2 1608.7863 1.19 141141 8618 2 1608.788415 805.4004 Interleukin enhancer-binding factor 3 OS=Homo sapiens OX=9606 GN=ILF3 PE=1 SV=3 5.45 1928.6 - 148784 - - - 1.3339 - 1.743 0.355 - 182.1 1 2 0 0.0021 14 0 0 0 3.43E+06 2.88E+06 - - - 3.0566 0.9996 221125_WJC_METTL3_EV_vs_WT_F10.08622.08622.3 8.92E-08 13/56 K.GQPDVVVKEDEEYKR.V "sp|P24752|THIL_HUMAN,tr|A0A5F9ZHJ7|A0A5F9ZHJ7_HUMAN,tr|A0A5F9ZHD4|A0A5F9ZHD4_HUMAN,tr|A0A5F9ZHJ0|A0A5F9ZHJ0_HUMAN,tr|A0A5F9ZHL1|A0A5F9ZHL1_HUMAN,tr|A0A5F9ZI66|A0A5F9ZI66_HUMAN" 6 1789.8846 1.38 141143 8622 3 1789.891097 597.6355 "Acetyl-CoA acetyltransferase, mitochondrial OS=Homo sapiens OX=9606 GN=ACAT1 PE=1 SV=1" 4.51 1929.2 - 179954 - - - 3.6058 - 2.828 0.55 - 200 1 2 1 0.0065 15 0 0 0 1.13E+08 8.23E+07 - - - 7.3828 0.9968 221125_WJC_METTL3_EV_vs_WT_F10.08627.08627.2 0.0382 Apr-34 R.SQDPTPPSAPQEATEGSK.V sp|Q9UPN7|PP6R1_HUMAN 1 1825.833 2.31 141148 8627 2 1825.83673 913.9238 Serine\threonine-protein phosphatase 6 regulatory subunit 1 OS=Homo sapiens OX=9606 GN=PPP6R1 PE=1 SV=5 4.14 1929.8 - 69232.2 - - - 2.0424 - 0.983 0.422 - 22 1 2 0 0.0037 18 0 0 0 1.96E+06 8.46E+05 - - - 2.1146 0.9998 221125_WJC_METTL3_EV_vs_WT_F10.08629.08629.3 0.00258 13/36 R.K[136.11]QDSGHLDLR[166.11].N "sp|Q86U44|MTA70_HUMAN,tr|B4E349|B4E349_HUMAN,tr|F5H6D8|F5H6D8_HUMAN,tr|B4DTN4|B4DTN4_HUMAN" 4 1185.6221 0.09 141149 8629 3 1185.62362 396.2146 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 6.75 1930.1 - 584697 - - - 1.2778 - 2.021 0.365 - 256.4 1 2 0 0.0015 10 0 0 0 1.68E+06 1.81E+07 - - - 4.6638 0.9999 221125_WJC_METTL3_EV_vs_WT_F10.08631.08631.4 8.26E-06 14/84 R.YSPSQNSPIHHIPSR.R "sp|Q9NYF8|BCLF1_HUMAN,tr|H0YF00|H0YF00_HUMAN,tr|E9PKI6|E9PKI6_HUMAN,tr|A0A1W2PQ43|A0A1W2PQ43_HUMAN,tr|E9PK91|E9PK91_HUMAN,tr|E9PJA7|E9PJA7_HUMAN,tr|E9PK09|E9PK09_HUMAN,tr|E9PQN2|E9PQN2_HUMAN" 8 1718.8489 3.04 141150 8631 4 1718.849635 430.7195 Bcl-2-associated transcription factor 1 OS=Homo sapiens OX=9606 GN=BCLAF1 PE=1 SV=2 8.76 1930.4 - 588436 - - - 0.4474 - 2.454 0.466 - 146.9 1 2 0 0.0008 15 0 0 0 3.45E+08 1.13E+08 - - - 3.6031 1 221125_WJC_METTL3_EV_vs_WT_F10.08636.08636.3 5.92E-11 15/56 R.YSPSQNSPIHHIPSR.R "sp|Q9NYF8|BCLF1_HUMAN,tr|H0YF00|H0YF00_HUMAN,tr|E9PKI6|E9PKI6_HUMAN,tr|A0A1W2PQ43|A0A1W2PQ43_HUMAN,tr|E9PK91|E9PK91_HUMAN,tr|E9PJA7|E9PJA7_HUMAN,tr|E9PK09|E9PK09_HUMAN,tr|E9PQN2|E9PQN2_HUMAN" 8 1718.8489 2.97 141155 8636 3 1718.849233 573.9569 Bcl-2-associated transcription factor 1 OS=Homo sapiens OX=9606 GN=BCLAF1 PE=1 SV=2 8.76 1931 - 291992 - - - 0.2135 - 2.719 0.642 - 334.7 1 2 0 0.0004 15 0 0 0 1.66E+08 5.60E+07 - - - 8.3076 1 221125_WJC_METTL3_EV_vs_WT_F10.08637.08637.3 5.02E-08 14/76 K.AQPAQPADEPAEKADEPMEH.- "sp|P25786|PSA1_HUMAN,tr|F5GX11|F5GX11_HUMAN" 2 2159.943 0.78 141156 8637 3 2159.943558 720.9883 Proteasome subunit alpha type-1 OS=Homo sapiens OX=9606 GN=PSMA1 PE=1 SV=1 4.08 1931.1 - 229347 - - - 0.2755 - 2.621 0.651 - 205.8 1 2 1 0.0006 20 0 0 0 5.79E+06 7.44E+06 - - - 8.1354 0.9999 221125_WJC_METTL3_EV_vs_WT_F10.08641.08641.4 7.73E-10 16/84 K.GQPDVVVKEDEEYKR.V "sp|P24752|THIL_HUMAN,tr|A0A5F9ZHJ7|A0A5F9ZHJ7_HUMAN,tr|A0A5F9ZHD4|A0A5F9ZHD4_HUMAN,tr|A0A5F9ZHJ0|A0A5F9ZHJ0_HUMAN,tr|A0A5F9ZHL1|A0A5F9ZHL1_HUMAN,tr|A0A5F9ZI66|A0A5F9ZI66_HUMAN" 6 1789.8846 1.22 141158 8641 4 1789.887094 448.4784 "Acetyl-CoA acetyltransferase, mitochondrial OS=Homo sapiens OX=9606 GN=ACAT1 PE=1 SV=1" 4.51 1931.6 - 893863 - - - 1.3694 - 3.445 0.533 - 252.3 1 2 1 0.0025 15 0 0 0 1.69E+08 1.39E+08 - - - 4.3071 0.9999 221125_WJC_METTL3_EV_vs_WT_F10.08643.08643.4 1.99E-05 Dec-84 R.YSPSQNSPIHHIPSR[166.11].R "sp|Q9NYF8|BCLF1_HUMAN,tr|H0YF00|H0YF00_HUMAN,tr|E9PKI6|E9PKI6_HUMAN,tr|A0A1W2PQ43|A0A1W2PQ43_HUMAN,tr|E9PK91|E9PK91_HUMAN,tr|E9PJA7|E9PJA7_HUMAN,tr|E9PK09|E9PK09_HUMAN,tr|E9PQN2|E9PQN2_HUMAN" 8 1728.8571 3.04 141160 8643 4 1728.857353 433.2216 Bcl-2-associated transcription factor 1 OS=Homo sapiens OX=9606 GN=BCLAF1 PE=1 SV=2 8.76 1931.9 - 283324 - - - 0.1255 - 2.256 0.446 - 104.5 1 2 0 0.0002 15 0 0 0 3.45E+08 1.13E+08 - - - 3.399 0.9999 221125_WJC_METTL3_EV_vs_WT_F10.08644.08644.3 3.74E-05 15/92 R.AAAGGQGSAVAAEAEPGK[136.11]EEPPAR[166.11].S sp|Q9GZT9|EGLN1_HUMAN 1 2238.0996 0.13 141161 8644 3 2238.099361 747.0405 Egl nine homolog 1 OS=Homo sapiens OX=9606 GN=EGLN1 PE=1 SV=1 4.49 1932 - 225940 - - - -0.088 - 3.043 0.498 - 139.3 1 2 1 -0.0002 24 0 0 0 1.11E+06 8.48E+06 - - - 6.6768 0.9986 221125_WJC_METTL3_EV_vs_WT_F10.08645.08645.3 0.000542 Sep-56 R.YSPSQNSPIHHIPSR[166.11].R "sp|Q9NYF8|BCLF1_HUMAN,tr|H0YF00|H0YF00_HUMAN,tr|E9PKI6|E9PKI6_HUMAN,tr|A0A1W2PQ43|A0A1W2PQ43_HUMAN,tr|E9PK91|E9PK91_HUMAN,tr|E9PJA7|E9PJA7_HUMAN,tr|E9PK09|E9PK09_HUMAN,tr|E9PQN2|E9PQN2_HUMAN" 8 1728.8571 2.97 141162 8645 3 1728.864341 577.293 Bcl-2-associated transcription factor 1 OS=Homo sapiens OX=9606 GN=BCLAF1 PE=1 SV=2 8.76 1932.1 - 120169 - - - 4.1675 - 1.997 0.396 - 85 1 2 0 0.0072 15 0 0 0 1.66E+08 5.60E+07 - - - 4.7578 0.9626 221125_WJC_METTL3_EV_vs_WT_F10.08650.08650.4 1.24E-05 Nov-72 M.IHIYLDK[136.11]ETGK[136.11]PK[136.11].G "sp|Q01844|EWS_HUMAN,tr|B0QYK0|B0QYK0_HUMAN,tr|H7BY36|H7BY36_HUMAN,tr|A0A0D9SFL3|A0A0D9SFL3_HUMAN,tr|C9JGE3|C9JGE3_HUMAN" 5 1564.9039 0.77 141165 8650 4 1564.90474 392.2333 RNA-binding protein EWS OS=Homo sapiens OX=9606 GN=EWSR1 PE=1 SV=1 8.44 1932.8 - 236112 - - - 0.5182 - 2.294 0.435 - 91.7 1 1 1 0.0008 13 0 0 0 4.44E+06 5.78E+06 - - - 3.3199 0.9999 221125_WJC_METTL3_EV_vs_WT_F10.08667.08667.3 3.78E-06 15/56 K.GQPDVVVK[136.11]EDEEYK[136.11]R[166.11].V "sp|P24752|THIL_HUMAN,tr|A0A5F9ZHJ7|A0A5F9ZHJ7_HUMAN,tr|A0A5F9ZHD4|A0A5F9ZHD4_HUMAN,tr|A0A5F9ZHJ0|A0A5F9ZHJ0_HUMAN,tr|A0A5F9ZHL1|A0A5F9ZHL1_HUMAN,tr|A0A5F9ZI66|A0A5F9ZI66_HUMAN" 6 1815.9213 1.38 141178 8667 3 1815.923699 606.3144 "Acetyl-CoA acetyltransferase, mitochondrial OS=Homo sapiens OX=9606 GN=ACAT1 PE=1 SV=1" 4.51 1934.8 - 1.21E+06 - - - 1.3139 - 3.266 0.568 - 399.8 1 2 1 0.0024 15 0 0 0 1.13E+08 8.17E+07 - - - 7.9603 0.9545 221125_WJC_METTL3_EV_vs_WT_F10.08670.08670.4 0.00425 Nov-72 M.IHIYLDKETGKPK.G "sp|Q01844|EWS_HUMAN,tr|B0QYK0|B0QYK0_HUMAN,tr|H7BY36|H7BY36_HUMAN,tr|A0A0D9SFL3|A0A0D9SFL3_HUMAN,tr|C9JGE3|C9JGE3_HUMAN" 5 1540.8613 0.77 141181 8670 4 1540.861789 386.2226 RNA-binding protein EWS OS=Homo sapiens OX=9606 GN=EWSR1 PE=1 SV=1 8.44 1935.2 - 209247 - - - 0.2985 - 2.218 0.422 - 100.2 1 1 1 0.0005 13 0 0 0 4.44E+06 5.78E+06 - - - 3.1943 0.9998 221125_WJC_METTL3_EV_vs_WT_F10.08683.08683.3 0.00018 Nov-80 K.QAEVANQETK[136.11]EDLPAENGETK[136.11].T "sp|P05114|HMGN1_HUMAN,tr|A6NEL0|A6NEL0_HUMAN,tr|A6NL93|A6NL93_HUMAN" 3 2316.1052 0.98 141188 8683 3 2316.104468 773.0423 Non-histone chromosomal protein HMG-14 OS=Homo sapiens OX=9606 GN=HMGN1 PE=1 SV=3 4.14 1937 - 265957 - - - -0.3221 - 2.666 0.461 - 84.3 1 2 1 -0.0007 21 0 0 0 8.56E+06 8.69E+06 - - - 6.0304 1 221125_WJC_METTL3_EV_vs_WT_F10.08685.08685.3 4.82E-08 17/48 Q.PDVVVKEDEEYKR.V "sp|P24752|THIL_HUMAN,tr|A0A5F9ZHJ7|A0A5F9ZHJ7_HUMAN,tr|A0A5F9ZHD4|A0A5F9ZHD4_HUMAN,tr|A0A5F9ZHJ0|A0A5F9ZHJ0_HUMAN,tr|A0A5F9ZHL1|A0A5F9ZHL1_HUMAN,tr|A0A5F9ZI66|A0A5F9ZI66_HUMAN" 6 1604.8046 1.47 141190 8685 3 1604.807666 535.9421 "Acetyl-CoA acetyltransferase, mitochondrial OS=Homo sapiens OX=9606 GN=ACAT1 PE=1 SV=1" 4.51 1937.2 - 682460 - - - 1.9093 - 3.496 0.612 - 582 1 1 1 0.0031 13 0 0 0 2.83E+07 1.93E+07 - - - 8.7559 0.9998 221125_WJC_METTL3_EV_vs_WT_F10.08691.08691.3 1.65E-06 Dec-68 R.SREDAGDNDDTEGAIGVR.N sp|Q9H0S4|DDX47_HUMAN 1 1875.8195 1.08 141194 8691 3 1875.823196 626.2804 Probable ATP-dependent RNA helicase DDX47 OS=Homo sapiens OX=9606 GN=DDX47 PE=1 SV=1 3.96 1938 - 261344 - - - 1.9826 - 2.143 0.565 - 176.3 1 2 1 0.0037 18 0 0 0 1.22E+07 1.13E+07 - - - 6.7361 0.9999 221125_WJC_METTL3_EV_vs_WT_F10.08699.08699.3 3.79E-06 14/36 R.TKYEHELALR.Q sp|P08779|K1C16_HUMAN 1 1258.667 1608.78 141199 8699 3 1258.669697 420.5629 "Keratin, type I cytoskeletal 16 OS=Homo sapiens OX=9606 GN=KRT16 PE=1 SV=4" 6.42 1939 - 742561 - - - 2.1539 - 2.78 0.544 - 320.1 1 2 1 0.0027 10 0 0 0 6.46E+07 4.01E+04 - - - 7.5903 1 221125_WJC_METTL3_EV_vs_WT_F10.08701.08701.3 1.89E-07 14/68 R.QHEQPGQGIAPDAVNGQR[166.11].R "sp|P50851|LRBA_HUMAN,tr|E9PEM5|E9PEM5_HUMAN,tr|A0A494BZW2|A0A494BZW2_HUMAN,tr|A0A494C1L5|A0A494C1L5_HUMAN,tr|A0A494C0R9|A0A494C0R9_HUMAN" 5 1910.9223 0.29 141200 8701 3 1910.922094 637.9814 Lipopolysaccharide-responsive and beige-like anchor protein OS=Homo sapiens OX=9606 GN=LRBA PE=1 SV=4 5.32 1939.3 - 256728 - - - -0.0848 - 2.629 0.535 - 219.1 1 2 0 -0.0002 18 0 0 0 1.65E+06 5.61E+06 - - - 6.9116 1 221125_WJC_METTL3_EV_vs_WT_F10.08704.08704.3 0.000234 Nov-60 R.WATHGVPSAVNSHPQR.S sp|O94808|GFPT2_HUMAN 1 1742.8601 1.09 141203 8704 3 1742.861317 581.9606 Glutamine--fructose-6-phosphate aminotransferase [isomerizing] 2 OS=Homo sapiens OX=9606 GN=GFPT2 PE=1 SV=3 9.76 1939.6 - 208909 - - - 0.6983 - 2.566 0.48 - 157.2 1 2 0 0.0012 16 0 0 0 3.17E+06 2.90E+06 - - - 6.3091 0.994 221125_WJC_METTL3_EV_vs_WT_F10.08708.08708.3 0.0129 Aug-68 R.QHEQPGQGIAPDAVNGQR.R "sp|P50851|LRBA_HUMAN,tr|E9PEM5|E9PEM5_HUMAN,tr|A0A494BZW2|A0A494BZW2_HUMAN,tr|A0A494C1L5|A0A494C1L5_HUMAN,tr|A0A494C0R9|A0A494C0R9_HUMAN" 5 1900.914 0.3 141205 8708 3 1900.914302 634.6453 Lipopolysaccharide-responsive and beige-like anchor protein OS=Homo sapiens OX=9606 GN=LRBA PE=1 SV=4 5.32 1940.2 - 124107 - - - 0.1662 - 1.489 0.232 - 22.5 1 2 0 0.0003 18 0 0 0 1.65E+06 5.53E+06 - - - 2.1178 0.9993 221125_WJC_METTL3_EV_vs_WT_F10.08709.08709.3 0.032 Dec-60 R.SPSPAHLPDDPK[136.11]VAEK[136.11].Q "sp|Q92615|LAR4B_HUMAN,tr|A0A087X183|A0A087X183_HUMAN,tr|H0Y641|H0Y641_HUMAN,tr|H0Y4V9|H0Y4V9_HUMAN" 4 1702.8861 1.81 141206 8709 3 1702.886114 568.636 La-related protein 4B OS=Homo sapiens OX=9606 GN=LARP4B PE=1 SV=3 5.36 1940.3 - 215797 - - - 0.0082 - 2.228 0.379 - 176.4 1 2 1 0 16 0 0 0 2.06E+07 1.14E+07 - - - 4.821 1 221125_WJC_METTL3_EV_vs_WT_F10.08714.08714.4 0.000327 16/90 R.WATHGVPSAVNSHPQR.S sp|O94808|GFPT2_HUMAN 1 1742.8601 1.21 141210 8714 4 1742.860774 436.7223 Glutamine--fructose-6-phosphate aminotransferase [isomerizing] 2 OS=Homo sapiens OX=9606 GN=GFPT2 PE=1 SV=3 9.76 1941 - 487044 - - - 0.3867 - 2.947 0.468 - 191.5 1 2 0 0.0007 16 0 0 0 7.70E+06 6.35E+06 - - - 3.68 1 221125_WJC_METTL3_EV_vs_WT_F10.08715.08715.4 7.22E-06 23/90 R.WATHGVPSAVNSHPQR[166.11].S sp|O94808|GFPT2_HUMAN 1 1752.8684 1.22 141211 8715 4 1752.86967 439.2244 Glutamine--fructose-6-phosphate aminotransferase [isomerizing] 2 OS=Homo sapiens OX=9606 GN=GFPT2 PE=1 SV=3 9.76 1941.1 - 340756 - - - 0.7416 - 3.333 0.518 - 348.3 1 2 0 0.0013 16 0 0 0 7.62E+06 6.25E+06 - - - 4.1584 0.9994 221125_WJC_METTL3_EV_vs_WT_F10.08718.08718.4 2.28E-05 14/90 R.SPSPAHLPDDPK[136.11]VAEK[136.11].Q "sp|Q92615|LAR4B_HUMAN,tr|A0A087X183|A0A087X183_HUMAN,tr|H0Y641|H0Y641_HUMAN,tr|H0Y4V9|H0Y4V9_HUMAN" 4 1702.8861 1.75 141212 8718 4 1702.889231 426.7288 La-related protein 4B OS=Homo sapiens OX=9606 GN=LARP4B PE=1 SV=3 5.36 1941.5 - 327715 - - - 1.8386 - 2.212 0.422 - 108.5 1 2 1 0.0031 16 0 0 0 3.47E+07 1.98E+07 - - - 3.1779 0.9998 221125_WJC_METTL3_EV_vs_WT_F10.08719.08719.4 0.0211 Sep-84 K.IDESSLTGESDHVK[136.11]K[136.11].S "sp|P20020|AT2B1_HUMAN,sp|P23634|AT2B4_HUMAN" 2 1659.8286 1.27 141213 8719 4 1659.828546 415.9644 Plasma membrane calcium-transporting ATPase 1 OS=Homo sapiens OX=9606 GN=ATP2B1 PE=1 SV=4 4.75 1941.6 - 349070 - - - -0.0596 - 2.005 0.388 - 65.9 1 2 0 -0.0001 15 0 0 0 1.04E+07 8.23E+06 - - - 2.852 0.9989 221125_WJC_METTL3_EV_vs_WT_F10.08722.08722.4 0.0262 Oct-84 K.IDESSLTGESDHVKK.S "sp|P20020|AT2B1_HUMAN,sp|P23634|AT2B4_HUMAN" 2 1643.8002 1.26 141216 8722 4 1643.801789 411.9573 Plasma membrane calcium-transporting ATPase 1 OS=Homo sapiens OX=9606 GN=ATP2B1 PE=1 SV=4 4.75 1941.9 - 285592 - - - 0.9393 - 1.657 0.298 - 41.8 1 2 0 0.0015 15 0 0 0 1.07E+07 8.43E+06 - - - 2.0001 1 221125_WJC_METTL3_EV_vs_WT_F10.08725.08725.3 2.78E-05 13/56 K.IDESSLTGESDHVK[136.11]K[136.11].S "sp|P20020|AT2B1_HUMAN,sp|P23634|AT2B4_HUMAN" 2 1659.8286 1.08 141217 8725 3 1659.830739 554.2835 Plasma membrane calcium-transporting ATPase 1 OS=Homo sapiens OX=9606 GN=ATP2B1 PE=1 SV=4 4.75 1942.4 - 316678 - - - 1.2616 - 2.833 0.572 - 286.3 1 2 0 0.0021 15 0 0 0 7.21E+06 6.69E+06 - - - 7.6339 0.9999 221125_WJC_METTL3_EV_vs_WT_F10.08726.08726.3 2.58E-08 14/56 R.QQQDTC[160.03]NSGIADIHR.L "sp|Q9UK61|TASOR_HUMAN,tr|A0A087X0F1|A0A087X0F1_HUMAN" 2 1741.7802 1.19 141218 8726 3 1741.78519 581.6007 Protein TASOR OS=Homo sapiens OX=9606 GN=TASOR PE=1 SV=3 5.21 1942.5 - 328443 - - - 2.8678 - 2.65 0.536 - 321.9 1 2 0 0.005 15 0 0 0 8.68E+06 7.29E+06 - - - 7.0575 0.9999 221125_WJC_METTL3_EV_vs_WT_F10.08727.08727.3 1.50E-06 15/76 K.ASVASEVSTTSSTSKPPTGR.R "sp|Q5SW79|CE170_HUMAN,tr|H0Y2V6|H0Y2V6_HUMAN" 2 1948.9702 1.14 141219 8727 3 1948.974682 650.664 Centrosomal protein of 170 kDa OS=Homo sapiens OX=9606 GN=CEP170 PE=1 SV=1 8.79 1942.6 - 401412 - - - 2.3181 - 2.753 0.501 - 205.8 1 2 0 0.0045 20 0 0 0 2.11E+07 1.85E+07 - - - 6.5812 1 221125_WJC_METTL3_EV_vs_WT_F10.08729.08729.3 4.68E-10 24/48 S.PSQNSPIHHIPSR.R "sp|Q9NYF8|BCLF1_HUMAN,tr|H0YF00|H0YF00_HUMAN,tr|E9PKI6|E9PKI6_HUMAN,tr|A0A1W2PQ43|A0A1W2PQ43_HUMAN,tr|E9PK91|E9PK91_HUMAN,tr|E9PJA7|E9PJA7_HUMAN,tr|E9PK09|E9PK09_HUMAN,tr|E9PQN2|E9PQN2_HUMAN" 8 1468.7535 2.99 141221 8729 3 1468.755658 490.5918 Bcl-2-associated transcription factor 1 OS=Homo sapiens OX=9606 GN=BCLAF1 PE=1 SV=2 10.18 1942.9 - 332395 - - - 1.4631 - 4.212 0.621 - 1026.5 1 1 0 0.0021 13 0 0 0 1.34E+07 4.47E+06 - - - 9.3616 1 221125_WJC_METTL3_EV_vs_WT_F10.08731.08731.3 3.82E-05 10/100 R.GGAAGEDEAGGPEGDPEEEDSQAETK.S "sp|O75410|TACC1_HUMAN,tr|E5RJG6|E5RJG6_HUMAN" 2 2531.0056 1.54 141223 8731 3 2531.008909 844.6758 Transforming acidic coiled-coil-containing protein 1 OS=Homo sapiens OX=9606 GN=TACC1 PE=1 SV=2 3.55 1943.1 - 139542 - - - 1.3236 - 2.288 0.596 - 74.3 1 2 0 0.0034 26 0 0 0 1.12E+07 7.25E+06 - - - 7.0881 0.9999 221125_WJC_METTL3_EV_vs_WT_F10.08733.08733.2 1.97E-06 Aug-38 K.SSATVTGEPPSYSSGSDSSK.A "sp|P35658|NU214_HUMAN,tr|A0A494C1F2|A0A494C1F2_HUMAN" 2 1929.844 2.31 141225 8733 2 1929.843677 965.9293 Nuclear pore complex protein Nup214 OS=Homo sapiens OX=9606 GN=NUP214 PE=1 SV=2 4.37 1943.4 - 107379 - - - -0.1466 - 1.948 0.634 - 64.8 1 2 0 -0.0003 20 0 0 0 2.69E+07 1.16E+07 - - - 5.363 0.9999 221125_WJC_METTL3_EV_vs_WT_F10.08738.08738.2 1.16E-05 Aug-38 K.SSATVTGEPPSYSSGSDSSK[136.11].A "sp|P35658|NU214_HUMAN,tr|A0A494C1F2|A0A494C1F2_HUMAN" 2 1937.8582 2.31 141228 8738 2 1937.859927 969.9364 Nuclear pore complex protein Nup214 OS=Homo sapiens OX=9606 GN=NUP214 PE=1 SV=2 4.37 1944.1 - 120370 - - - 0.9118 - 1.799 0.608 - 73.8 1 2 0 0.0018 20 0 0 0 2.69E+07 1.16E+07 - - - 4.9749 0.9999 221125_WJC_METTL3_EV_vs_WT_F10.08740.08740.3 4.29E-06 Sep-56 K.NEEPSEEEIDAPKPK.K sp|Q9NR30|DDX21_HUMAN 1 1710.7948 1.19 141230 8740 3 1710.799051 571.2722 Nucleolar RNA helicase 2 OS=Homo sapiens OX=9606 GN=DDX21 PE=1 SV=5 4.14 1944.3 - 273240 - - - 2.4702 - 2.012 0.5 - 105.4 1 2 0 0.0042 15 0 0 0 7.32E+06 6.15E+06 - - - 5.9376 1 221125_WJC_METTL3_EV_vs_WT_F10.08745.08745.3 1.79E-06 21/76 K.ASVASEVSTTSSTSK[136.11]PPTGR[166.11].R "sp|Q5SW79|CE170_HUMAN,tr|H0Y2V6|H0Y2V6_HUMAN" 2 1966.9926 1.16 141233 8745 3 1966.993408 656.6715 Centrosomal protein of 170 kDa OS=Homo sapiens OX=9606 GN=CEP170 PE=1 SV=1 8.79 1944.9 - 772119 - - - 0.3935 - 2.856 0.529 - 428.6 1 2 0 0.0008 20 0 0 0 2.17E+07 1.88E+07 - - - 6.9835 0.9999 221125_WJC_METTL3_EV_vs_WT_F10.08746.08746.3 0.000146 Nov-76 K.SSATVTGEPPSYSSGSDSSK.A "sp|P35658|NU214_HUMAN,tr|A0A494C1F2|A0A494C1F2_HUMAN" 2 1929.844 1.97 141234 8746 3 1929.849101 644.2886 Nuclear pore complex protein Nup214 OS=Homo sapiens OX=9606 GN=NUP214 PE=1 SV=2 4.37 1945.1 - 154855 - - - 2.6639 - 2.182 0.512 - 91.9 1 2 0 0.0051 20 0 0 0 8.53E+06 4.32E+06 - - - 6.1398 0.9984 221125_WJC_METTL3_EV_vs_WT_F10.08750.08750.4 0.00431 15/90 R.SPSPAHLPDDPKVAEK.Q "sp|Q92615|LAR4B_HUMAN,tr|A0A087X183|A0A087X183_HUMAN,tr|H0Y641|H0Y641_HUMAN,tr|H0Y4V9|H0Y4V9_HUMAN" 4 1686.8577 1.41 141236 8750 4 1686.861399 422.7217 La-related protein 4B OS=Homo sapiens OX=9606 GN=LARP4B PE=1 SV=3 5.36 1945.7 - 756440 - - - 2.1928 - 2.076 0.376 - 161.7 1 2 1 0.0037 16 0 0 0 2.01E+07 1.43E+07 - - - 2.755 0.9998 221125_WJC_METTL3_EV_vs_WT_F10.08753.08753.3 3.39E-06 Sep-72 K.IKADPDGPEAQAEAC[160.03]SGER.T "sp|Q9NX24|NHP2_HUMAN,tr|J3QSY4|J3QSY4_HUMAN,tr|D6RCB9|D6RCB9_HUMAN,tr|D6RC52|D6RC52_HUMAN" 4 1999.8905 1.29 141239 8753 3 1999.893289 667.6375 H\ACA ribonucleoprotein complex subunit 2 OS=Homo sapiens OX=9606 GN=NHP2 PE=1 SV=1 4.18 1946 - 124115 - - - 1.3781 - 2.094 0.56 - 65.1 1 2 1 0.0028 19 0 0 0 6.02E+06 4.67E+06 - - - 6.5984 0.9999 221125_WJC_METTL3_EV_vs_WT_F10.08756.08756.4 3.38E-08 16/84 K.GQPDVVVK[136.11]EDEEYK[136.11]R[166.11].V "sp|P24752|THIL_HUMAN,tr|A0A5F9ZHJ7|A0A5F9ZHJ7_HUMAN,tr|A0A5F9ZHD4|A0A5F9ZHD4_HUMAN,tr|A0A5F9ZHJ0|A0A5F9ZHJ0_HUMAN,tr|A0A5F9ZHL1|A0A5F9ZHL1_HUMAN,tr|A0A5F9ZI66|A0A5F9ZI66_HUMAN" 6 1815.9213 1.28 141241 8756 4 1815.922429 454.9876 "Acetyl-CoA acetyltransferase, mitochondrial OS=Homo sapiens OX=9606 GN=ACAT1 PE=1 SV=1" 4.51 1946.4 - 1.98E+06 - - - 0.6146 - 3.325 0.562 - 209.3 1 2 1 0.0011 15 0 0 0 1.69E+08 1.33E+08 - - - 4.5472 1 221125_WJC_METTL3_EV_vs_WT_F10.08760.08760.3 1.60E-09 16/100 R.GGAAGEDEAGGPEGDPEEEDSQAETK[136.11].S "sp|O75410|TACC1_HUMAN,tr|E5RJG6|E5RJG6_HUMAN" 2 2539.0198 1.54 141245 8760 3 2540.021312 847.3472 Transforming acidic coiled-coil-containing protein 1 OS=Homo sapiens OX=9606 GN=TACC1 PE=1 SV=2 3.55 1946.8 - 324668 - - - 394.4644 - 3.065 0.736 - 221.9 1 2 0 1.0016 26 0 0 0 1.12E+07 7.25E+06 - - - 9.0451 0.9996 221125_WJC_METTL3_EV_vs_WT_F10.08773.08773.3 4.06E-05 Nov-64 K.GPGDSTR[166.11]PSK[136.11]PGPVSWK[136.11].S "sp|O75880|SCO1_HUMAN,tr|J3QL56|J3QL56_HUMAN" 2 1777.9322 1.02 141254 8773 3 1777.9263 593.6513 "Protein SCO1 homolog, mitochondrial OS=Homo sapiens OX=9606 GN=SCO1 PE=1 SV=1" 9.99 1948.5 - 206181 - - - -3.2915 - 2.117 0.44 - 148.2 1 2 0 -0.0059 17 0 0 0 8.71E+06 8.53E+06 - - - 5.3387 0.9999 221125_WJC_METTL3_EV_vs_WT_F10.08778.08778.4 9.47E-06 17/96 K.GPGDSTRPSKPGPVSWK.S "sp|O75880|SCO1_HUMAN,tr|J3QL56|J3QL56_HUMAN" 2 1751.8955 0.98 141257 8778 4 1751.898752 438.9811 "Protein SCO1 homolog, mitochondrial OS=Homo sapiens OX=9606 GN=SCO1 PE=1 SV=1" 9.99 1949.2 - 497903 - - - 1.8665 - 2.721 0.469 - 223.7 1 2 0 0.0033 17 0 0 0 1.39E+07 1.42E+07 - - - 3.6548 0.9999 221125_WJC_METTL3_EV_vs_WT_F10.08779.08779.3 0.00505 14/64 K.GPGDSTRPSKPGPVSWK.S "sp|O75880|SCO1_HUMAN,tr|J3QL56|J3QL56_HUMAN" 2 1751.8955 1.03 141258 8779 3 1751.897937 584.9724 "Protein SCO1 homolog, mitochondrial OS=Homo sapiens OX=9606 GN=SCO1 PE=1 SV=1" 9.99 1949.3 - 313340 - - - 1.4013 - 2.581 0.397 - 225.1 1 2 0 0.0025 17 0 0 0 8.71E+06 8.47E+06 - - - 5.3609 0.9997 221125_WJC_METTL3_EV_vs_WT_F10.08781.08781.3 0.00525 Sep-80 R.DPAQPMSPGEATQSGAR[166.11]PADR[166.11].Y sp|Q9BQG0|MBB1A_HUMAN 1 2157.9976 0.85 141260 8781 3 2157.99949 720.3398 Myb-binding protein 1A OS=Homo sapiens OX=9606 GN=MYBBP1A PE=1 SV=2 4.56 1949.6 - 175906 - - - 0.867 - 1.918 0.38 - 60.4 1 2 0 0.0019 21 0 0 0 3.21E+06 3.77E+06 - - - 4.3375 0.9987 221125_WJC_METTL3_EV_vs_WT_F10.08792.08792.4 0.00214 Dec-96 K.GPGDSTR[166.11]PSK[136.11]PGPVSWK[136.11].S "sp|O75880|SCO1_HUMAN,tr|J3QL56|J3QL56_HUMAN" 2 1777.9322 0.98 141267 8792 4 1777.936245 445.4903 "Protein SCO1 homolog, mitochondrial OS=Homo sapiens OX=9606 GN=SCO1 PE=1 SV=1" 9.99 1951 - 900950 - - - 2.3021 - 2.361 0.311 - 61 1 2 0 0.0041 17 0 0 0 1.39E+07 1.42E+07 - - - 2.2301 0.99 221125_WJC_METTL3_EV_vs_WT_F10.08794.08794.3 0.00316 Oct-56 K.KVESTGAVPEFKEEK.L sp|Q6YN16|HSDL2_HUMAN 1 1676.8621 0.58 141269 8794 3 1676.867724 559.9613 Hydroxysteroid dehydrogenase-like protein 2 OS=Homo sapiens OX=9606 GN=HSDL2 PE=1 SV=1 4.95 1951.3 - 243062 - - - 3.3437 - 2.246 0.293 - 149.7 1 2 1 0.0056 15 0 0 0 2.45E+07 4.26E+07 - - - 3.9165 0.9983 221125_WJC_METTL3_EV_vs_WT_F10.08798.08798.3 0.000367 Dec-60 K.QRLDKDGIPVSSEAER.H "sp|Q9Y282|ERGI3_HUMAN,tr|A6PVJ2|A6PVJ2_HUMAN,tr|A0A0C4DH46|A0A0C4DH46_HUMAN,tr|H0Y621|H0Y621_HUMAN,tr|H0Y5K5|H0Y5K5_HUMAN" 5 1798.9173 1.25 141271 8798 3 1798.923352 600.6464 Endoplasmic reticulum-Golgi intermediate compartment protein 3 OS=Homo sapiens OX=9606 GN=ERGIC3 PE=1 SV=1 4.78 1951.8 - 191369 - - - 3.342 - 2.269 0.435 - 159.5 1 2 2 0.006 16 0 0 0 3.30E+06 2.64E+06 - - - 5.4905 1 221125_WJC_METTL3_EV_vs_WT_F10.08810.08810.3 1.65E-11 23/52 K.HYYEVSC[160.03]HDQGLC[160.03]R[166.11].V "sp|Q92499|DDX1_HUMAN,tr|A0A7I2V2M5|A0A7I2V2M5_HUMAN,tr|A0A087X2G1|A0A087X2G1_HUMAN,tr|A0A7I2V430|A0A7I2V430_HUMAN,tr|A0A7I2V421|A0A7I2V421_HUMAN,tr|A0A7I2V4F0|A0A7I2V4F0_HUMAN,tr|A0A7I2V4Q0|A0A7I2V4Q0_HUMAN,tr|A0A7I2YQD0|A0A7I2YQD0_HUMAN,tr|A0A7I2V5X8|A0A7I2V5X8_HUMAN,tr|A0A7I2V4J3|A0A7I2V4J3_HUMAN,tr|A0A087WZ71|A0A087WZ71_HUMAN,tr|A0A7I2YQ77|A0A7I2YQ77_HUMAN" 12 1832.7598 1.56 141280 8810 3 1832.760544 611.9272 ATP-dependent RNA helicase DDX1 OS=Homo sapiens OX=9606 GN=DDX1 PE=1 SV=2 5.99 1953.3 - 603520 - - - 0.4016 - 3.999 0.509 - 1002.1 1 2 0 0.0007 14 0 0 0 3.25E+07 2.08E+07 - - - 7.8981 0.9999 221125_WJC_METTL3_EV_vs_WT_F10.08812.08812.3 0.000423 Nov-68 R.TTASSELSEKPAESVTSK.K "sp|Q71F23|CENPU_HUMAN,tr|D6R9S4|D6R9S4_HUMAN,tr|Q09GN1|Q09GN1_HUMAN" 3 1850.9109 1.71 141282 8812 3 1850.913591 617.9776 Centromere protein U OS=Homo sapiens OX=9606 GN=CENPU PE=1 SV=1 4.78 1953.5 - 203903 - - - 1.4447 - 2.18 0.477 - 119.1 1 2 0 0.0027 18 0 0 0 4.52E+06 2.64E+06 - - - 5.7979 0.9946 221125_WJC_METTL3_EV_vs_WT_F10.08813.08813.4 0.106 Aug-90 K.ATVAAFAASEGHSHPR.V "sp|O14910|LIN7A_HUMAN,sp|Q9NUP9|LIN7C_HUMAN,tr|H0YIA8|H0YIA8_HUMAN,tr|G3V1D4|G3V1D4_HUMAN,tr|H0YI92|H0YI92_HUMAN" 5 1607.7805 1.55 141283 8813 4 1607.783978 402.9524 Protein lin-7 homolog A OS=Homo sapiens OX=9606 GN=LIN7A PE=1 SV=2 6.96 1953.6 - 146706 - - - 2.1925 - 1.393 0.26 - 40.5 1 2 0 0.0035 16 0 0 0 2.13E+06 1.38E+06 - - - 1.6048 1 221125_WJC_METTL3_EV_vs_WT_F10.08819.08819.3 8.13E-08 22/52 K.HYYEVSC[160.03]HDQGLC[160.03]R.V "sp|Q92499|DDX1_HUMAN,tr|A0A7I2V2M5|A0A7I2V2M5_HUMAN,tr|A0A087X2G1|A0A087X2G1_HUMAN,tr|A0A7I2V430|A0A7I2V430_HUMAN,tr|A0A7I2V421|A0A7I2V421_HUMAN,tr|A0A7I2V4F0|A0A7I2V4F0_HUMAN,tr|A0A7I2V4Q0|A0A7I2V4Q0_HUMAN,tr|A0A7I2YQD0|A0A7I2YQD0_HUMAN,tr|A0A7I2V5X8|A0A7I2V5X8_HUMAN,tr|A0A7I2V4J3|A0A7I2V4J3_HUMAN,tr|A0A087WZ71|A0A087WZ71_HUMAN,tr|A0A7I2YQ77|A0A7I2YQ77_HUMAN" 12 1822.7515 1.56 141287 8819 3 1822.754672 608.5911 ATP-dependent RNA helicase DDX1 OS=Homo sapiens OX=9606 GN=DDX1 PE=1 SV=2 5.99 1954.4 - 1.84E+06 - - - 1.7194 - 3.962 0.722 - 771.9 1 2 0 0.0031 14 0 0 0 3.25E+07 2.08E+07 - - - 10.2475 0.9999 221125_WJC_METTL3_EV_vs_WT_F10.08820.08820.3 0.000399 18/48 K.SSLHESLHIGQSR[166.11].T "sp|P82094|TMF1_HUMAN,tr|F8WF45|F8WF45_HUMAN,tr|A0A2R8Y7M0|A0A2R8Y7M0_HUMAN" 3 1459.7407 1.54 141288 8820 3 1459.744438 487.5875 TATA element modulatory factor OS=Homo sapiens OX=9606 GN=TMF1 PE=1 SV=2 6.66 1954.5 - 657099 - - - 2.5539 - 2.87 0.463 - 362.7 1 2 0 0.0037 13 0 0 0 7.97E+07 5.19E+07 - - - 6.5595 0.9969 221125_WJC_METTL3_EV_vs_WT_F10.08824.08824.4 5.93E-05 17/84 K.K[136.11]VESTGAVPEFK[136.11]EEK[136.11].L sp|Q6YN16|HSDL2_HUMAN 1 1700.9047 0.56 141292 8824 4 1700.907779 426.2335 Hydroxysteroid dehydrogenase-like protein 2 OS=Homo sapiens OX=9606 GN=HSDL2 PE=1 SV=1 4.95 1955 - 425953 - - - 1.8002 - 2.652 0.313 - 175 1 2 1 0.0031 15 0 0 0 1.28E+07 2.27E+07 - - - 2.2985 0.9999 221125_WJC_METTL3_EV_vs_WT_F10.08825.08825.3 1.37E-06 15/48 K.GHQFSC[160.03]VC[160.03]LHGDR.K "sp|Q92499|DDX1_HUMAN,tr|A0A7I2V2M5|A0A7I2V2M5_HUMAN,tr|A0A087X2G1|A0A087X2G1_HUMAN,tr|A0A7I2V430|A0A7I2V430_HUMAN,tr|A0A7I2V4F0|A0A7I2V4F0_HUMAN,tr|A0A087WZ71|A0A087WZ71_HUMAN,tr|A0A7I2YQ77|A0A7I2YQ77_HUMAN" 7 1571.6722 2.11 141293 8825 3 1571.677349 524.898 ATP-dependent RNA helicase DDX1 OS=Homo sapiens OX=9606 GN=DDX1 PE=1 SV=2 6.9 1955.1 - 328924 - - - 3.2984 - 2.811 0.565 - 298.3 1 2 0 0.0052 13 0 0 0 8.26E+06 3.91E+06 - - - 7.64 1 221125_WJC_METTL3_EV_vs_WT_F10.08828.08828.3 6.18E-05 15/40 M.GHQQLYWSHPR[166.11].K "sp|P62273|RS29_HUMAN,tr|A0A2R8Y851|A0A2R8Y851_HUMAN" 2 1417.6879 1.03 141294 8828 3 1417.690144 473.5699 40S ribosomal protein S29 OS=Homo sapiens OX=9606 GN=RPS29 PE=1 SV=2 8.76 1955.6 - 2.18E+06 - - - 1.5927 - 2.829 0.538 - 495.6 1 2 0 0.0023 11 0 0 0 2.09E+08 2.03E+08 - - - 7.4918 1 221125_WJC_METTL3_EV_vs_WT_F10.08829.08829.3 2.15E-05 16/40 M.GHQQLYWSHPR.K "sp|P62273|RS29_HUMAN,tr|A0A2R8Y851|A0A2R8Y851_HUMAN" 2 1407.6796 1.03 141295 8829 3 1407.682098 470.2338 40S ribosomal protein S29 OS=Homo sapiens OX=9606 GN=RPS29 PE=1 SV=2 8.76 1955.6 - 1.73E+06 - - - 1.7632 - 2.862 0.508 - 561.6 1 2 0 0.0025 11 0 0 0 2.10E+08 2.03E+08 - - - 7.1902 1 221125_WJC_METTL3_EV_vs_WT_F10.08831.08831.4 4.95E-09 16/72 K.GHQFSC[160.03]VC[160.03]LHGDR.K "sp|Q92499|DDX1_HUMAN,tr|A0A7I2V2M5|A0A7I2V2M5_HUMAN,tr|A0A087X2G1|A0A087X2G1_HUMAN,tr|A0A7I2V430|A0A7I2V430_HUMAN,tr|A0A7I2V4F0|A0A7I2V4F0_HUMAN,tr|A0A087WZ71|A0A087WZ71_HUMAN,tr|A0A7I2YQ77|A0A7I2YQ77_HUMAN" 7 1571.6722 2.02 141297 8831 4 1571.675057 393.9253 ATP-dependent RNA helicase DDX1 OS=Homo sapiens OX=9606 GN=DDX1 PE=1 SV=2 6.9 1955.8 - 638290 - - - 1.8401 - 3.039 0.632 - 370.2 1 2 0 0.0029 13 0 0 0 7.56E+06 3.74E+06 - - - 5.1382 1 221125_WJC_METTL3_EV_vs_WT_F10.08832.08832.4 6.03E-07 Dec-78 K.HYYEVSC[160.03]HDQGLC[160.03]R.V "sp|Q92499|DDX1_HUMAN,tr|A0A7I2V2M5|A0A7I2V2M5_HUMAN,tr|A0A087X2G1|A0A087X2G1_HUMAN,tr|A0A7I2V430|A0A7I2V430_HUMAN,tr|A0A7I2V421|A0A7I2V421_HUMAN,tr|A0A7I2V4F0|A0A7I2V4F0_HUMAN,tr|A0A7I2V4Q0|A0A7I2V4Q0_HUMAN,tr|A0A7I2YQD0|A0A7I2YQD0_HUMAN,tr|A0A7I2V5X8|A0A7I2V5X8_HUMAN,tr|A0A7I2V4J3|A0A7I2V4J3_HUMAN,tr|A0A087WZ71|A0A087WZ71_HUMAN,tr|A0A7I2YQ77|A0A7I2YQ77_HUMAN" 12 1822.7515 1.19 141298 8832 4 1822.75729 456.6952 ATP-dependent RNA helicase DDX1 OS=Homo sapiens OX=9606 GN=DDX1 PE=1 SV=2 5.99 1955.9 - 581368 - - - 3.1557 - 2.604 0.634 - 212.5 1 2 0 0.0058 14 0 0 0 5.40E+06 4.54E+06 - - - 5.0911 0.9997 221125_WJC_METTL3_EV_vs_WT_F10.08834.08834.3 0.00275 13/68 R.TTASSELSEK[136.11]PAESVTSK[136.11].K "sp|Q71F23|CENPU_HUMAN,tr|D6R9S4|D6R9S4_HUMAN,tr|Q09GN1|Q09GN1_HUMAN" 3 1866.9393 1.67 141300 8834 3 1866.944308 623.3204 Centromere protein U OS=Homo sapiens OX=9606 GN=CENPU PE=1 SV=1 4.78 1956.2 - 395390 - - - 2.6734 - 2.081 0.447 - 155.8 1 2 0 0.005 18 0 0 0 4.40E+06 2.64E+06 - - - 5.3471 0.9999 221125_WJC_METTL3_EV_vs_WT_F10.08837.08837.3 3.31E-07 13/80 K.GEGGTPAPASLPGGSKEEEEK.A "sp|Q96PM9|Z385A_HUMAN,tr|F8VQ24|F8VQ24_HUMAN,tr|F8VRY0|F8VRY0_HUMAN,tr|H0YI55|H0YI55_HUMAN" 4 2025.9491 1.55 141303 8837 3 2025.950953 676.3236 Zinc finger protein 385A OS=Homo sapiens OX=9606 GN=ZNF385A PE=1 SV=2 4.33 1956.6 - 213396 - - - 0.9176 - 2.548 0.556 - 127.9 1 2 1 0.0019 21 0 0 0 4.05E+06 2.61E+06 - - - 6.9807 0.9977 221125_WJC_METTL3_EV_vs_WT_F10.08839.08839.2 0.0197 28-Jul K.GSC[160.03]GIGGGIGGGSSR.L "sp|P02533|K1C14_HUMAN,sp|P08779|K1C16_HUMAN,tr|K7ENV3|K7ENV3_HUMAN" 3 1277.5782 999 141305 8839 2 1277.582354 639.7964 "Keratin, type I cytoskeletal 14 OS=Homo sapiens OX=9606 GN=KRT14 PE=1 SV=4" 8.25 1956.8 - 121747 - - - 3.2147 - 1.623 0.399 - 98 1 2 0 0.0041 15 0 0 0 4.51E+06 0.00E+00 - - - 3.1773 0.9997 221125_WJC_METTL3_EV_vs_WT_F10.08842.08842.4 6.41E-05 15/84 K.KVESTGAVPEFKEEK.L sp|Q6YN16|HSDL2_HUMAN 1 1676.8621 0.55 141307 8842 4 1676.865054 420.2228 Hydroxysteroid dehydrogenase-like protein 2 OS=Homo sapiens OX=9606 GN=HSDL2 PE=1 SV=1 4.95 1957.2 - 407172 - - - 1.7515 - 2.925 0.465 - 175.4 1 2 1 0.0029 15 0 0 0 1.30E+07 2.35E+07 - - - 3.6566 1 221125_WJC_METTL3_EV_vs_WT_F10.08844.08844.3 1.94E-07 19/48 K.SSLHESLHIGQSR.T "sp|P82094|TMF1_HUMAN,tr|F8WF45|F8WF45_HUMAN,tr|A0A2R8Y7M0|A0A2R8Y7M0_HUMAN" 3 1449.7324 1.54 141308 8844 3 1449.7347 484.2514 TATA element modulatory factor OS=Homo sapiens OX=9606 GN=TMF1 PE=1 SV=2 6.66 1957.4 - 4.37E+06 - - - 1.5589 - 2.959 0.529 - 426.6 1 2 0 0.0023 13 0 0 0 7.97E+07 5.19E+07 - - - 7.3785 1 221125_WJC_METTL3_EV_vs_WT_F10.08845.08845.3 3.82E-08 20/52 K.R[166.11]PAEDMEEEQAFK[136.11]R[166.11].S "sp|P61978|HNRPK_HUMAN,tr|S4R457|S4R457_HUMAN,tr|Q5T6W2|Q5T6W2_HUMAN" 3 1762.8303 1.06 141309 8845 3 1762.832707 588.6174 Heterogeneous nuclear ribonucleoprotein K OS=Homo sapiens OX=9606 GN=HNRNPK PE=1 SV=1 4.59 1957.5 - 839039 - - - 1.3807 - 3.908 0.634 - 717.9 1 2 0 0.0024 14 0 0 0 2.30E+07 2.17E+07 - - - 9.2301 1 221125_WJC_METTL3_EV_vs_WT_F10.08846.08846.3 1.85E-05 22/52 K.RPAEDMEEEQAFKR.S "sp|P61978|HNRPK_HUMAN,tr|S4R457|S4R457_HUMAN,tr|Q5T6W2|Q5T6W2_HUMAN" 3 1734.7995 1.09 141310 8846 3 1734.801964 579.2738 Heterogeneous nuclear ribonucleoprotein K OS=Homo sapiens OX=9606 GN=HNRNPK PE=1 SV=1 4.59 1957.6 - 909792 - - - 1.4013 - 4.269 0.645 - 861.1 1 2 0 0.0024 14 0 0 0 2.29E+07 2.11E+07 - - - 9.5875 0.9999 221125_WJC_METTL3_EV_vs_WT_F10.08848.08848.3 2.84E-09 15/64 R.SSEEPTEKEPPGQLQVK.A "sp|Q9ULV3|CIZ1_HUMAN,tr|Q5SYW2|Q5SYW2_HUMAN,tr|F5H2X7|F5H2X7_HUMAN,tr|H0Y5D5|H0Y5D5_HUMAN,tr|A0A494C0L7|A0A494C0L7_HUMAN,tr|Q9BTG3|Q9BTG3_HUMAN" 6 1881.932 3.42 141312 8848 3 1881.933662 628.3179 Cip1-interacting zinc finger protein OS=Homo sapiens OX=9606 GN=CIZ1 PE=1 SV=2 4.49 1957.9 - 545405 - - - 0.89 - 3.034 0.506 - 226.1 1 2 1 0.0017 17 0 0 0 1.16E+08 3.39E+07 - - - 6.9848 1 221125_WJC_METTL3_EV_vs_WT_F10.08849.08849.4 0.000185 Nov-78 K.HYYEVSC[160.03]HDQGLC[160.03]R[166.11].V "sp|Q92499|DDX1_HUMAN,tr|A0A7I2V2M5|A0A7I2V2M5_HUMAN,tr|A0A087X2G1|A0A087X2G1_HUMAN,tr|A0A7I2V430|A0A7I2V430_HUMAN,tr|A0A7I2V421|A0A7I2V421_HUMAN,tr|A0A7I2V4F0|A0A7I2V4F0_HUMAN,tr|A0A7I2V4Q0|A0A7I2V4Q0_HUMAN,tr|A0A7I2YQD0|A0A7I2YQD0_HUMAN,tr|A0A7I2V5X8|A0A7I2V5X8_HUMAN,tr|A0A7I2V4J3|A0A7I2V4J3_HUMAN,tr|A0A087WZ71|A0A087WZ71_HUMAN,tr|A0A7I2YQ77|A0A7I2YQ77_HUMAN" 12 1832.7598 1.2 141313 8849 4 1832.761402 459.1972 ATP-dependent RNA helicase DDX1 OS=Homo sapiens OX=9606 GN=DDX1 PE=1 SV=2 5.99 1958 - 532277 - - - 0.8697 - 2.242 0.528 - 119 1 2 0 0.0016 14 0 0 0 5.40E+06 4.49E+06 - - - 4.1151 1 221125_WJC_METTL3_EV_vs_WT_F10.08851.08851.4 0.000907 19/78 K.R[166.11]PAEDMEEEQAFK[136.11]R[166.11].S "sp|P61978|HNRPK_HUMAN,tr|S4R457|S4R457_HUMAN,tr|Q5T6W2|Q5T6W2_HUMAN" 3 1762.8303 1.14 141315 8851 4 1762.830907 441.7148 Heterogeneous nuclear ribonucleoprotein K OS=Homo sapiens OX=9606 GN=HNRNPK PE=1 SV=1 4.59 1958.2 - 483702 - - - 0.3596 - 3.083 0.498 - 412.1 1 2 0 0.0006 14 0 0 0 1.03E+07 9.06E+06 - - - 3.9702 0.9999 221125_WJC_METTL3_EV_vs_WT_F10.08852.08852.4 1.17E-07 14/72 R.ER[166.11]HPGSFDVVHVK[136.11].D "sp|P62701|RS4X_HUMAN,sp|P22090|RS4Y1_HUMAN,tr|C9JEH7|C9JEH7_HUMAN" 3 1523.7964 0.001 141316 8852 4 1523.798573 381.9564 "40S ribosomal protein S4, X isoform OS=Homo sapiens OX=9606 GN=RPS4X PE=1 SV=2" 7.02 1958.3 - 425070 - - - 1.4385 - 2.249 0.558 - 136 1 2 1 0.0022 13 0 0 0 0.00E+00 3.59E+06 - - - 4.3827 0.9996 221125_WJC_METTL3_EV_vs_WT_F10.08854.08854.3 0.00924 Dec-80 K.GEGGTPAPASLPGGSK[136.11]EEEEK[136.11].A "sp|Q96PM9|Z385A_HUMAN,tr|F8VQ24|F8VQ24_HUMAN,tr|F8VRY0|F8VRY0_HUMAN,tr|H0YI55|H0YI55_HUMAN" 4 2041.9775 1.55 141318 8854 3 2041.97748 681.6664 Zinc finger protein 385A OS=Homo sapiens OX=9606 GN=ZNF385A PE=1 SV=2 4.33 1958.6 - 286684 - - - -0.0069 - 2.58 0.399 - 53.1 1 2 1 0 21 0 0 0 4.05E+06 2.61E+06 - - - 5.2607 0.9995 221125_WJC_METTL3_EV_vs_WT_F10.08856.08856.2 2.20E-06 24-Oct K.SSLHESLHIGQSR[166.11].T "sp|P82094|TMF1_HUMAN,tr|F8WF45|F8WF45_HUMAN,tr|A0A2R8Y7M0|A0A2R8Y7M0_HUMAN" 3 1459.7407 1.92 141320 8856 2 1459.736382 730.8776 TATA element modulatory factor OS=Homo sapiens OX=9606 GN=TMF1 PE=1 SV=2 6.66 1958.9 - 89747.3 - - - -2.9649 - 1.857 0.57 - 247.7 1 2 0 -0.0043 13 0 0 0 2.41E+06 1.25E+06 - - - 4.8382 0.9998 221125_WJC_METTL3_EV_vs_WT_F10.08860.08860.4 0.000309 13/84 R.GLVMVK[136.11]PGSIK[136.11]PHQK[136.11].V sp|P49411|EFTU_HUMAN 1 1641.9815 1.06 141323 8860 4 1641.984272 411.5026 "Elongation factor Tu, mitochondrial OS=Homo sapiens OX=9606 GN=TUFM PE=1 SV=2" 10.3 1959.4 - 303041 - - - 1.7083 - 1.766 0.393 - 87.3 1 2 0 0.0028 15 0 0 0 9.69E+06 9.15E+06 - - - 2.8494 0.8921 221125_WJC_METTL3_EV_vs_WT_F10.08861.08861.4 0.439 Sep-84 R.GLVMVKPGSIKPHQK.V sp|P49411|EFTU_HUMAN 1 1617.9389 1.06 141324 8861 4 1617.941714 405.492 "Elongation factor Tu, mitochondrial OS=Homo sapiens OX=9606 GN=TUFM PE=1 SV=2" 10.3 1959.5 - 285118 - - - 1.7596 - 1.596 0.122 - 45.9 1 2 0 0.0028 15 0 0 0 9.69E+06 9.17E+06 - - - 0.4544 1 221125_WJC_METTL3_EV_vs_WT_F10.08865.08865.4 4.86E-07 18/78 K.RPAEDMEEEQAFKR.S "sp|P61978|HNRPK_HUMAN,tr|S4R457|S4R457_HUMAN,tr|Q5T6W2|Q5T6W2_HUMAN" 3 1734.7995 1.1 141326 8865 4 1734.802446 434.7072 Heterogeneous nuclear ribonucleoprotein K OS=Homo sapiens OX=9606 GN=HNRNPK PE=1 SV=1 4.59 1960 - 956852 - - - 1.6792 - 3.312 0.592 - 383 1 2 0 0.0029 14 0 0 0 1.03E+07 9.37E+06 - - - 4.8138 0.9999 221125_WJC_METTL3_EV_vs_WT_F10.08867.08867.3 2.58E-09 16/40 K.R[166.11]DENWDK[136.11]EIEK[136.11].M sp|Q96A49|SYAP1_HUMAN 1 1486.7262 1.34 141328 8867 3 1486.72786 496.5827 Synapse-associated protein 1 OS=Homo sapiens OX=9606 GN=SYAP1 PE=1 SV=1 4.51 1960.2 - 601418 - - - 1.0883 - 2.66 0.597 - 192.5 1 2 1 0.0016 11 0 0 0 2.77E+08 2.07E+08 - - - 7.9748 0.9999 221125_WJC_METTL3_EV_vs_WT_F10.08868.08868.2 2.50E-09 14/20 M.GHQQLYWSHPR[166.11].K "sp|P62273|RS29_HUMAN,tr|A0A2R8Y851|A0A2R8Y851_HUMAN" 2 1417.6879 1.21 141329 8868 2 1417.688038 709.8512 40S ribosomal protein S29 OS=Homo sapiens OX=9606 GN=RPS29 PE=1 SV=2 8.76 1960.4 - 470693 - - - 0.1072 - 3.003 0.5 - 832.4 1 2 0 0.0002 11 0 0 0 5.28E+06 4.35E+06 - - - 5.7087 1 221125_WJC_METTL3_EV_vs_WT_F10.08871.08871.3 9.48E-09 19/56 R.QELSHALYQHDAAC[160.03]R[166.11].V "sp|Q9UMS4|PRP19_HUMAN,tr|F5GY56|F5GY56_HUMAN,tr|F5H2I0|F5H2I0_HUMAN" 3 1807.8299 0.88 141330 8871 3 1807.831385 603.6173 Pre-mRNA-processing factor 19 OS=Homo sapiens OX=9606 GN=PRPF19 PE=1 SV=1 5.99 1960.8 - 1.94E+06 - - - 0.8015 - 3.349 0.625 - 658.9 1 2 0 0.0014 15 0 0 0 4.92E+07 5.61E+07 - - - 8.6616 0.9997 221125_WJC_METTL3_EV_vs_WT_F10.08872.08872.3 3.72E-06 Oct-64 K.ISC[160.03]AGPQTYK[136.11]EHLEGQK[136.11].H sp|Q96KR1|ZFR_HUMAN 1 1960.9648 1.04 141331 8872 3 1960.967383 654.6622 Zinc finger RNA-binding protein OS=Homo sapiens OX=9606 GN=ZFR PE=1 SV=2 6.75 1960.9 - 235555 - - - 1.3371 - 2.227 0.486 - 113.9 1 2 1 0.0026 17 0 0 0 3.67E+06 3.53E+06 - - - 5.9804 0.9993 221125_WJC_METTL3_EV_vs_WT_F10.08874.08874.4 3.47E-06 17/84 R.QELSHALYQHDAAC[160.03]R.V "sp|Q9UMS4|PRP19_HUMAN,tr|F5GY56|F5GY56_HUMAN,tr|F5H2I0|F5H2I0_HUMAN" 3 1797.8217 0.78 141333 8874 4 1797.824194 450.4627 Pre-mRNA-processing factor 19 OS=Homo sapiens OX=9606 GN=PRPF19 PE=1 SV=1 5.99 1961 - 2.09E+06 - - - 1.4061 - 2.567 0.312 - 248.5 1 2 0 0.0025 15 0 0 0 5.47E+07 7.03E+07 - - - 2.2783 0.9999 221125_WJC_METTL3_EV_vs_WT_F10.08880.08880.4 1.64E-08 15/102 K.IK[136.11]ELNNTC[160.03]EPVVTQPK[136.11]PK[136.11].L "sp|Q92598|HS105_HUMAN,tr|Q5TBM3|Q5TBM3_HUMAN,tr|A0A0A0MSM0|A0A0A0MSM0_HUMAN" 3 2118.1569 0.13 141337 8880 4 2118.157999 530.5465 Heat shock protein 105 kDa OS=Homo sapiens OX=9606 GN=HSPH1 PE=1 SV=1 8.18 1961.8 - 3.84E+06 - - - 0.5066 - 2.525 0.615 - 171.6 1 2 1 0.0011 18 0 0 0 1.37E+07 1.06E+08 - - - 4.896 1 221125_WJC_METTL3_EV_vs_WT_F10.08881.08881.3 3.51E-10 18/60 K.QTAISQPASGNTFSHH.S "sp|Q14157|UBP2L_HUMAN,tr|F8W726|F8W726_HUMAN,tr|Q5VU77|Q5VU77_HUMAN" 3 1681.7808 - 141338 8881 3 1681.781058 561.6009 Ubiquitin-associated protein 2-like OS=Homo sapiens OX=9606 GN=UBAP2L PE=1 SV=2 6.92 1961.9 - 1.27E+06 - - - 0.1261 - 3.517 0.621 - 567 1 1 0 0.0002 16 0 0 0 - - - - - 8.6903 0.9999 221125_WJC_METTL3_EV_vs_WT_F10.08882.08882.4 4.79E-05 13/84 R.QELSHALYQHDAAC[160.03]R[166.11].V "sp|Q9UMS4|PRP19_HUMAN,tr|F5GY56|F5GY56_HUMAN,tr|F5H2I0|F5H2I0_HUMAN" 3 1807.8299 0.98 141339 8882 4 1807.831073 452.9648 Pre-mRNA-processing factor 19 OS=Homo sapiens OX=9606 GN=PRPF19 PE=1 SV=1 5.99 1961.9 - 3.44E+06 - - - 0.6289 - 2.452 0.466 - 172.4 1 2 0 0.0011 15 0 0 0 5.38E+07 5.48E+07 - - - 3.6027 1 221125_WJC_METTL3_EV_vs_WT_F10.08883.08883.3 4.47E-12 21/68 K.IK[136.11]ELNNTC[160.03]EPVVTQPK[136.11]PK[136.11].L "sp|Q92598|HS105_HUMAN,tr|Q5TBM3|Q5TBM3_HUMAN,tr|A0A0A0MSM0|A0A0A0MSM0_HUMAN" 3 2118.1569 0.12 141340 8883 3 2118.170953 707.0596 Heat shock protein 105 kDa OS=Homo sapiens OX=9606 GN=HSPH1 PE=1 SV=1 8.18 1962 - 993660 - - - 6.6223 - 3.52 0.703 - 559.1 1 2 1 0.014 18 0 0 0 3.80E+06 3.20E+07 - - - 9.5076 0.9999 221125_WJC_METTL3_EV_vs_WT_F10.08885.08885.4 8.01E-06 14/102 K.IKELNNTC[160.03]EPVVTQPKPK.L "sp|Q92598|HS105_HUMAN,tr|Q5TBM3|Q5TBM3_HUMAN,tr|A0A0A0MSM0|A0A0A0MSM0_HUMAN" 3 2094.1143 0.13 141342 8885 4 2094.115509 524.5359 Heat shock protein 105 kDa OS=Homo sapiens OX=9606 GN=HSPH1 PE=1 SV=1 8.18 1962.3 - 478297 - - - 0.5649 - 2.077 0.508 - 136.8 1 2 1 0.0012 18 0 0 0 1.37E+07 1.06E+08 - - - 3.8977 0.9999 221125_WJC_METTL3_EV_vs_WT_F10.08886.08886.2 9.63E-09 14/20 M.GHQQLYWSHPR.K "sp|P62273|RS29_HUMAN,tr|A0A2R8Y851|A0A2R8Y851_HUMAN" 2 1407.6796 1.21 141343 8886 2 1407.679419 704.8471 40S ribosomal protein S29 OS=Homo sapiens OX=9606 GN=RPS29 PE=1 SV=2 8.76 1962.4 - 462999 - - - -0.1399 - 3.005 0.375 - 815.6 1 2 0 -0.0002 11 0 0 0 5.28E+06 4.35E+06 - - - 4.7872 0.9998 221125_WJC_METTL3_EV_vs_WT_F10.08889.08889.3 9.58E-05 Sep-56 R.KQAEETYENIPGQSK.L "sp|O00410|IPO5_HUMAN,tr|E7ETV3|E7ETV3_HUMAN,tr|E7ETV8|E7ETV8_HUMAN,tr|C9JXE0|C9JXE0_HUMAN,tr|C9JQT6|C9JQT6_HUMAN,tr|C9JZD8|C9JZD8_HUMAN,tr|E7EWK4|E7EWK4_HUMAN,tr|E7EV12|E7EV12_HUMAN,tr|E7EX05|E7EX05_HUMAN,tr|C9J875|C9J875_HUMAN,tr|E7EQT5|E7EQT5_HUMAN,tr|E7ESZ1|E7ESZ1_HUMAN" 12 1720.8268 1.35 141346 8889 3 1720.829091 574.6162 Importin-5 OS=Homo sapiens OX=9606 GN=IPO5 PE=1 SV=4 4.79 1962.8 - 348646 - - - 1.3348 - 1.802 0.431 - 81.2 1 2 0 0.0023 15 0 0 0 1.06E+07 7.81E+06 - - - 4.8812 0.9998 221125_WJC_METTL3_EV_vs_WT_F10.08895.08895.3 0.000185 14/40 K.RDENWDKEIEK.M sp|Q96A49|SYAP1_HUMAN 1 1460.6896 1.34 141350 8895 3 1460.690323 487.9038 Synapse-associated protein 1 OS=Homo sapiens OX=9606 GN=SYAP1 PE=1 SV=1 4.51 1963.5 - 1.22E+07 - - - 0.5141 - 2.851 0.431 - 312.3 1 2 1 0.0008 11 0 0 0 2.77E+08 2.07E+08 - - - 6.3213 0.9996 221125_WJC_METTL3_EV_vs_WT_F10.08896.08896.4 0.000574 13/84 R.EQLEEEEEAKHNLEK.Q sp|P35579|MYH9_HUMAN 1 1853.8643 1.19 141351 8896 4 1853.867367 464.4734 Myosin-9 OS=Homo sapiens OX=9606 GN=MYH9 PE=1 SV=4 4.35 1963.6 - 1.62E+06 - - - 1.6538 - 2.781 0.428 - 131.5 1 2 1 0.0031 15 0 0 0 6.60E+07 5.57E+07 - - - 3.3164 0.9999 221125_WJC_METTL3_EV_vs_WT_F10.08897.08897.3 3.30E-08 17/56 R.EQLEEEEEAKHNLEK.Q sp|P35579|MYH9_HUMAN 1 1853.8643 1.21 141352 8897 3 1853.865451 618.962 Myosin-9 OS=Homo sapiens OX=9606 GN=MYH9 PE=1 SV=4 4.35 1963.6 - 1.25E+06 - - - 0.6203 - 3.135 0.583 - 398 1 2 1 0.0011 15 0 0 0 5.37E+07 4.44E+07 - - - 8.0211 1 221125_WJC_METTL3_EV_vs_WT_F10.08899.08899.3 0.000292 18/56 R.KLDYGQHVVAGTPGR.V "sp|P38919|IF4A3_HUMAN,tr|I3L3H2|I3L3H2_HUMAN" 2 1596.8372 1.46 141354 8899 3 1596.838619 533.2864 Eukaryotic initiation factor 4A-III OS=Homo sapiens OX=9606 GN=EIF4A3 PE=1 SV=4 8.6 1963.8 - 1.45E+06 - - - 0.8642 - 3.135 0.531 - 400.6 1 2 0 0.0014 15 0 0 0 2.91E+07 1.99E+07 - - - 7.4413 1 221125_WJC_METTL3_EV_vs_WT_F10.08900.08900.3 3.10E-05 18/56 R.K[136.11]LDYGQHVVAGTPGR[166.11].V "sp|P38919|IF4A3_HUMAN,tr|I3L3H2|I3L3H2_HUMAN" 2 1614.8597 1.46 141355 8900 3 1614.860625 539.2938 Eukaryotic initiation factor 4A-III OS=Homo sapiens OX=9606 GN=EIF4A3 PE=1 SV=4 8.6 1963.9 - 650348 - - - 0.5672 - 3.311 0.579 - 480.3 1 2 0 0.0009 15 0 0 0 2.91E+07 1.99E+07 - - - 8.1191 0.9745 221125_WJC_METTL3_EV_vs_WT_F10.08902.08902.2 0.437 20-Sep K.RDENWDKEIEK.M sp|Q96A49|SYAP1_HUMAN 1 1460.6896 1.44 141357 8902 2 1460.685813 731.3521 Synapse-associated protein 1 OS=Homo sapiens OX=9606 GN=SYAP1 PE=1 SV=1 4.51 1964.2 - 254551 - - - -2.5734 - 1.966 0.245 - 182.1 1 2 1 -0.0038 11 0 0 0 6.54E+06 4.53E+06 - - - 2.6781 0.9999 221125_WJC_METTL3_EV_vs_WT_F10.08905.08905.3 1.72E-07 16/64 R.SSEEPTEK[136.11]EPPGQLQVK[136.11].A "sp|Q9ULV3|CIZ1_HUMAN,tr|Q5SYW2|Q5SYW2_HUMAN,tr|F5H2X7|F5H2X7_HUMAN,tr|H0Y5D5|H0Y5D5_HUMAN,tr|A0A494C0L7|A0A494C0L7_HUMAN,tr|Q9BTG3|Q9BTG3_HUMAN" 6 1897.9604 3.42 141358 8905 3 1897.963857 633.6607 Cip1-interacting zinc finger protein OS=Homo sapiens OX=9606 GN=CIZ1 PE=1 SV=2 4.49 1964.6 - 1.18E+06 - - - 1.8283 - 2.768 0.589 - 266.8 1 2 1 0.0035 17 0 0 0 1.16E+08 3.39E+07 - - - 7.6779 0.9999 221125_WJC_METTL3_EV_vs_WT_F10.08907.08907.3 4.81E-07 Dec-68 K.IKELNNTC[160.03]EPVVTQPKPK.L "sp|Q92598|HS105_HUMAN,tr|Q5TBM3|Q5TBM3_HUMAN,tr|A0A0A0MSM0|A0A0A0MSM0_HUMAN" 3 2094.1143 0.12 141360 8907 3 2094.11227 699.0454 Heat shock protein 105 kDa OS=Homo sapiens OX=9606 GN=HSPH1 PE=1 SV=1 8.18 1964.8 - 465491 - - - -0.9818 - 2.517 0.602 - 153 1 2 1 -0.0021 18 0 0 0 3.80E+06 3.20E+07 - - - 7.5497 1 221125_WJC_METTL3_EV_vs_WT_F10.08908.08908.3 9.03E-06 Dec-88 R.AAPSTAPAEATPPK[136.11]PGEAEAPPK[136.11].H sp|O95817|BAG3_HUMAN 1 2200.1347 0.13 141361 8908 3 2200.132471 734.3855 BAG family molecular chaperone regulator 3 OS=Homo sapiens OX=9606 GN=BAG3 PE=1 SV=3 4.79 1965 - 319405 - - - -0.9963 - 2.652 0.514 - 100.4 1 2 0 -0.0022 23 0 0 0 5.65E+05 4.33E+06 - - - 6.558 0.999 221125_WJC_METTL3_EV_vs_WT_F10.08909.08909.2 8.77E-05 14/20 K.R[166.11]DENWDK[136.11]EIEK[136.11].M sp|Q96A49|SYAP1_HUMAN 1 1486.7262 1.44 141362 8909 2 1486.72579 744.3704 Synapse-associated protein 1 OS=Homo sapiens OX=9606 GN=SYAP1 PE=1 SV=1 4.51 1965.1 - 307611 - - - -0.304 - 2.925 0.486 - 608.7 1 2 1 -0.0005 11 0 0 0 6.54E+06 4.53E+06 - - - 5.534 0.9993 221125_WJC_METTL3_EV_vs_WT_F10.08910.08910.4 0.000807 Nov-84 R.K[136.11]LDYGQHVVAGTPGR[166.11].V "sp|P38919|IF4A3_HUMAN,tr|I3L3H2|I3L3H2_HUMAN" 2 1614.8597 1.61 141363 8910 4 1614.862556 404.7222 Eukaryotic initiation factor 4A-III OS=Homo sapiens OX=9606 GN=EIF4A3 PE=1 SV=4 8.6 1965.2 - 280582 - - - 1.763 - 2.383 0.323 - 115.1 1 2 0 0.0028 15 0 0 0 5.64E+06 3.50E+06 - - - 2.3473 0.9996 221125_WJC_METTL3_EV_vs_WT_F10.08913.08913.4 0.0022 16/84 R.EQLEEEEEAK[136.11]HNLEK[136.11].Q sp|P35579|MYH9_HUMAN 1 1869.8927 1.19 141364 8913 4 1869.892609 468.4805 Myosin-9 OS=Homo sapiens OX=9606 GN=MYH9 PE=1 SV=4 4.35 1965.6 - 6.49E+06 - - - -0.0492 - 2.796 0.412 - 244.7 1 2 1 -0.0001 15 0 0 0 6.60E+07 5.57E+07 - - - 3.1799 0.9982 221125_WJC_METTL3_EV_vs_WT_F10.08918.08918.3 0.011 Nov-40 K.R[166.11]DENWDKEIEK[136.11].M sp|Q96A49|SYAP1_HUMAN 1 1478.712 - 141369 8918 3 1478.71314 493.9113 Synapse-associated protein 1 OS=Homo sapiens OX=9606 GN=SYAP1 PE=1 SV=1 4.51 1966.1 - 707951 - - - 0.7425 - 1.92 0.326 - 171.1 1 2 1 0.0011 11 0 0 0 - - - - - 4.0274 0.9989 221125_WJC_METTL3_EV_vs_WT_F10.08921.08921.3 0.00239 Sep-64 K.ISC[160.03]AGPQTYKEHLEGQK.H sp|Q96KR1|ZFR_HUMAN 1 1944.9364 1.06 141372 8921 3 1944.939443 649.3194 Zinc finger RNA-binding protein OS=Homo sapiens OX=9606 GN=ZFR PE=1 SV=2 6.75 1966.5 - 249426 - - - 1.5846 - 1.801 0.427 - 68.6 1 2 1 0.0031 17 0 0 0 3.67E+06 3.46E+06 - - - 4.7861 0.9998 221125_WJC_METTL3_EV_vs_WT_F10.08922.08922.3 4.11E-06 Nov-64 K.DQGPDK[136.11]ENSGAIEASVK[136.11].L sp|Q69YN4|VIR_HUMAN 1 1759.8559 0.63 141373 8922 3 1759.855274 587.6259 Protein virilizer homolog OS=Homo sapiens OX=9606 GN=VIRMA PE=1 SV=2 4.32 1966.6 - 220458 - - - -0.3682 - 2.409 0.472 - 160.7 1 2 1 -0.0006 17 0 0 0 1.14E+06 1.82E+06 - - - 6.0233 0.9945 221125_WJC_METTL3_EV_vs_WT_F10.08925.08925.4 0.00555 Oct-90 K.VPEPC[160.03]HPKVPEPC[160.03]QPK.V "sp|P35321|SPR1A_HUMAN,sp|P22528|SPR1B_HUMAN" 2 1897.9179 89.12 141374 8925 4 1897.920119 475.4867 Cornifin-A OS=Homo sapiens OX=9606 GN=SPRR1A PE=1 SV=2 6.71 1967 - 900467 - - - 1.1823 - 2.018 0.281 - 59.7 1 2 1 0.0022 16 0 0 0 1.75E+07 1.97E+05 - - - 1.9185 1 221125_WJC_METTL3_EV_vs_WT_F10.08926.08926.3 2.88E-08 15/60 K.HTGPNSPDTANDGFVR[166.11].L "sp|P55795|HNRH2_HUMAN,sp|P31943|HNRH1_HUMAN,tr|E5RGH4|E5RGH4_HUMAN,tr|E7EQJ0|E7EQJ0_HUMAN,tr|D6RIH9|D6RIH9_HUMAN,tr|D6RJ04|D6RJ04_HUMAN,tr|E5RGV0|E5RGV0_HUMAN,tr|D6RFM3|D6RFM3_HUMAN,tr|E9PCY7|E9PCY7_HUMAN,tr|D6RIT2|D6RIT2_HUMAN,tr|D6R9T0|D6R9T0_HUMAN,tr|D6RIU0|D6RIU0_HUMAN,tr|H0YAQ2|H0YAQ2_HUMAN,tr|D6RAM1|D6RAM1_HUMAN,tr|D6RBM0|D6RBM0_HUMAN,tr|G8JLB6|G8JLB6_HUMAN,tr|D6RDU3|D6RDU3_HUMAN" 17 1693.7684 1.17 141375 8926 3 1693.76775 565.5967 Heterogeneous nuclear ribonucleoprotein H2 OS=Homo sapiens OX=9606 GN=HNRNPH2 PE=1 SV=1 5.21 1967.2 - 751915 - - - -0.3725 - 3.496 0.569 - 324.1 1 2 0 -0.0006 16 0 0 0 1.52E+07 1.30E+07 - - - 8.0951 0.9981 221125_WJC_METTL3_EV_vs_WT_F10.08932.08932.3 0.00428 Aug-56 R.THYSNIEANESEEVR[166.11].Q "sp|P04632|CPNS1_HUMAN,tr|A0A075B7C0|A0A075B7C0_HUMAN,tr|A0A0C4DGQ5|A0A0C4DGQ5_HUMAN,tr|K7ELJ7|K7ELJ7_HUMAN,tr|U3KQE2|U3KQE2_HUMAN,tr|K7EIV0|K7EIV0_HUMAN,tr|K7EM73|K7EM73_HUMAN" 7 1786.7997 0.95 141381 8932 3 1786.794422 596.6072 Calpain small subunit 1 OS=Homo sapiens OX=9606 GN=CAPNS1 PE=1 SV=1 4.48 1967.9 - 185522 - - - -2.9768 - 1.614 0.361 - 32.7 1 2 0 -0.0053 15 0 0 0 9.70E+05 1.02E+06 - - - 3.8125 0.9613 221125_WJC_METTL3_EV_vs_WT_F10.08933.08933.2 0.000345 30-Jul N.QSNNQQSNFEAVQSGK.K "sp|Q6Y7W6|GGYF2_HUMAN,tr|A0A7I2V3H7|A0A7I2V3H7_HUMAN,tr|I1E4Y6|I1E4Y6_HUMAN,tr|A0A7I2V516|A0A7I2V516_HUMAN,tr|A0A7I2V3H0|A0A7I2V3H0_HUMAN,tr|A0A7I2V361|A0A7I2V361_HUMAN" 6 1764.8027 11.87 141382 8933 2 1764.807126 883.4086 GRB10-interacting GYF protein 2 OS=Homo sapiens OX=9606 GN=GIGYF2 PE=1 SV=1 6 1968.1 - 156506 - - - 2.5057 - 1.529 0.536 - 129.9 1 1 0 0.0044 16 0 0 0 1.29E+06 1.09E+05 - - - 4.0424 0.9982 221125_WJC_METTL3_EV_vs_WT_F10.08938.08938.4 0.0089 13/84 R.KLDYGQHVVAGTPGR.V "sp|P38919|IF4A3_HUMAN,tr|I3L3H2|I3L3H2_HUMAN" 2 1596.8372 1.61 141385 8938 4 1596.842634 400.2166 Eukaryotic initiation factor 4A-III OS=Homo sapiens OX=9606 GN=EIF4A3 PE=1 SV=4 8.6 1968.6 - 415355 - - - 3.3786 - 2.44 0.33 - 167.3 1 2 0 0.0054 15 0 0 0 5.64E+06 3.50E+06 - - - 2.416 0.9438 221125_WJC_METTL3_EV_vs_WT_F10.08943.08943.4 0.336 Sep-96 K.NK[136.11]QGLETDNK[136.11]ELAC[160.03]EVK[136.11].V sp|P35580|MYH10_HUMAN 1 1999.0107 0.68 141390 8943 4 1999.016431 500.7599 Myosin-10 OS=Homo sapiens OX=9606 GN=MYH10 PE=1 SV=3 4.87 1969.2 - 191569 - - - 2.8894 - 1.86 0.226 - 74.2 1 2 2 0.0058 17 0 0 0 1.26E+06 1.86E+06 - - - 1.407 0.9968 221125_WJC_METTL3_EV_vs_WT_F10.08944.08944.4 0.0138 Aug-78 R.TVIIHDRPDITHPR.H "sp|Q9NWH9|SLTM_HUMAN,tr|H7C3F4|H7C3F4_HUMAN" 2 1668.906 1.75 141391 8944 4 1668.908094 418.2338 SAFB-like transcription modulator OS=Homo sapiens OX=9606 GN=SLTM PE=1 SV=2 6.61 1969.3 - 191032 - - - 1.2625 - 1.73 0.275 - 54 2 2 0 0.0021 14 0 0 0 7.01E+06 4.01E+06 - - - 1.5891 0.9998 221125_WJC_METTL3_EV_vs_WT_F10.08946.08946.3 0.0133 Sep-60 K.K[136.11]EDSSDATQVPQASLK[136.11].A sp|Q9NX31|OSER1_HUMAN 1 1718.8658 1.52 141393 8946 3 1718.865464 573.9625 Oxidative stress-responsive serine-rich protein 1 OS=Homo sapiens OX=9606 GN=OSER1 PE=1 SV=2 4.56 1969.6 - 90151.1 - - - -0.171 - 1.975 0.379 - 90.8 1 2 0 -0.0003 16 0 0 0 1.36E+06 8.98E+05 - - - 4.5116 1 221125_WJC_METTL3_EV_vs_WT_F10.08951.08951.3 1.90E-07 14/68 R.EYSSELNAPSQESDSHPR[166.11].K "sp|P49756|RBM25_HUMAN,tr|E9PQU5|E9PQU5_HUMAN" 2 2041.8853 1.01 141396 8951 3 2041.889531 681.6357 RNA-binding protein 25 OS=Homo sapiens OX=9606 GN=RBM25 PE=1 SV=3 4.4 1970.3 - 345417 - - - 2.0912 - 2.891 0.62 - 228.2 1 2 0 0.0043 18 0 0 0 2.11E+07 2.09E+07 - - - 8.0947 0.9999 221125_WJC_METTL3_EV_vs_WT_F10.08952.08952.3 0.000256 18/68 R.EYSSELNAPSQESDSHPR.K "sp|P49756|RBM25_HUMAN,tr|E9PQU5|E9PQU5_HUMAN" 2 2031.877 1.01 141397 8952 3 2031.882736 678.2996 RNA-binding protein 25 OS=Homo sapiens OX=9606 GN=RBM25 PE=1 SV=3 4.4 1970.4 - 336886 - - - 2.8274 - 3.106 0.537 - 485.9 1 2 0 0.0057 18 0 0 0 2.11E+07 2.09E+07 - - - 7.3475 0.9706 221125_WJC_METTL3_EV_vs_WT_F10.08954.08954.3 2.54E-05 Nov-56 K.EMAK[136.11]DVIEEHGPSEK[136.11].A "sp|P51114|FXR1_HUMAN,tr|H7C4S4|H7C4S4_HUMAN,tr|B4DXZ6|B4DXZ6_HUMAN" 3 1713.8215 2.49 141399 8954 3 1713.838302 572.2811 Fragile X mental retardation syndrome-related protein 1 OS=Homo sapiens OX=9606 GN=FXR1 PE=1 SV=3 4.57 1970.6 - 124916 - - - 9.8324 - 2.118 0.463 - 96.8 1 2 1 0.0169 15 0 0 0 4.09E+06 1.64E+06 - - - 5.6556 1 221125_WJC_METTL3_EV_vs_WT_F10.08959.08959.3 2.44E-12 22/88 K.GPSAAGEQEPDK[136.11]ESGASVDEVAR[166.11].Q "sp|P50579|MAP2_HUMAN,tr|G3V1U3|G3V1U3_HUMAN,tr|F8VSC4|F8VSC4_HUMAN" 3 2303.0632 0.3 141402 8959 3 2303.069108 768.695 Methionine aminopeptidase 2 OS=Homo sapiens OX=9606 GN=METAP2 PE=1 SV=1 4.08 1971.4 - 396061 - - - 2.5514 - 3.764 0.692 - 460.1 1 2 1 0.0059 23 0 0 0 2.18E+06 7.34E+06 - - - 9.363 0.9999 221125_WJC_METTL3_EV_vs_WT_F10.08960.08960.3 2.67E-08 15/68 R.ASQPDLVDTPTSSK[136.11]PQPK[136.11].R sp|P46013|KI67_HUMAN 1 1910.992 4.63 141403 8960 3 1910.99804 638.0046 Proliferation marker protein Ki-67 OS=Homo sapiens OX=9606 GN=MKI67 PE=1 SV=2 6 1971.5 - 272617 - - - 3.1491 - 3.125 0.573 - 272.4 1 2 0 0.006 18 0 0 0 3.00E+07 6.49E+06 - - - 7.764 0.9603 221125_WJC_METTL3_EV_vs_WT_F10.08964.08964.2 0.628 Feb-30 K.HTGPNSPDTANDGFVR[166.11].L "sp|P55795|HNRH2_HUMAN,sp|P31943|HNRH1_HUMAN,tr|E5RGH4|E5RGH4_HUMAN,tr|E7EQJ0|E7EQJ0_HUMAN,tr|D6RIH9|D6RIH9_HUMAN,tr|D6RJ04|D6RJ04_HUMAN,tr|E5RGV0|E5RGV0_HUMAN,tr|D6RFM3|D6RFM3_HUMAN,tr|E9PCY7|E9PCY7_HUMAN,tr|D6RIT2|D6RIT2_HUMAN,tr|D6R9T0|D6R9T0_HUMAN,tr|D6RIU0|D6RIU0_HUMAN,tr|H0YAQ2|H0YAQ2_HUMAN,tr|D6RAM1|D6RAM1_HUMAN,tr|D6RBM0|D6RBM0_HUMAN,tr|G8JLB6|G8JLB6_HUMAN,tr|D6RDU3|D6RDU3_HUMAN" 17 1693.7684 1.04 141407 8964 2 1693.771712 847.8915 Heterogeneous nuclear ribonucleoprotein H2 OS=Homo sapiens OX=9606 GN=HNRNPH2 PE=1 SV=1 5.21 1972 - 33596.7 - - - 1.9666 - 0.646 0.349 - 8.3 5 2 0 0.0033 16 0 0 0 2.06E+05 1.97E+05 - - - 0.2312 0.9999 221125_WJC_METTL3_EV_vs_WT_F10.08974.08974.3 1.61E-08 17/60 R.RADLNQGIGEPQSPSR.R sp|Q96C19|EFHD2_HUMAN 1 1723.8602 1.37 141415 8974 3 1723.867046 575.6273 EF-hand domain-containing protein D2 OS=Homo sapiens OX=9606 GN=EFHD2 PE=1 SV=1 6.07 1973.4 - 168601 - - - 3.9951 - 3.48 0.574 - 420.9 1 2 0 0.0069 16 0 0 0 2.77E+06 2.01E+06 - - - 8.1373 1 221125_WJC_METTL3_EV_vs_WT_F10.08978.08978.2 1.23E-08 Dec-38 K.SSATVTGEPPSYSSGSDSSK.A "sp|P35658|NU214_HUMAN,tr|A0A494C1F2|A0A494C1F2_HUMAN" 2 1929.844 2.1 141418 8978 2 1929.850956 965.9293 Nuclear pore complex protein Nup214 OS=Homo sapiens OX=9606 GN=NUP214 PE=1 SV=2 4.37 1973.9 - 155150 - - - 3.6252 - 2.475 0.686 - 206.1 1 2 0 0.007 20 0 0 0 1.05E+07 5.00E+06 - - - 6.3336 0.9981 221125_WJC_METTL3_EV_vs_WT_F10.08984.08984.4 1.43E-05 14/96 R.QGR[166.11]PVVIC[160.03]DK[136.11]EDTETIK[136.11].N "sp|Q06210|GFPT1_HUMAN,tr|A0A6I8PRN4|A0A6I8PRN4_HUMAN" 2 2013.0411 1.13 141423 8984 4 2013.049557 504.2676 Glutamine--fructose-6-phosphate aminotransferase [isomerizing] 1 OS=Homo sapiens OX=9606 GN=GFPT1 PE=1 SV=3 4.78 1974.6 - 281745 - - - 4.1956 - 2.128 0.457 - 149.1 1 2 1 0.0084 17 0 0 0 4.80E+07 4.24E+07 - - - 3.4636 1 221125_WJC_METTL3_EV_vs_WT_F10.08985.08985.3 1.90E-11 17/88 K.GPSAAGEQEPDKESGASVDEVAR.Q "sp|P50579|MAP2_HUMAN,tr|G3V1U3|G3V1U3_HUMAN,tr|F8VSC4|F8VSC4_HUMAN" 3 2285.0408 0.3 141424 8985 3 2285.047928 762.6875 Methionine aminopeptidase 2 OS=Homo sapiens OX=9606 GN=METAP2 PE=1 SV=1 4.08 1974.7 - 213426 - - - 3.136 - 3.75 0.704 - 358.9 1 2 1 0.0072 23 0 0 0 2.18E+06 7.30E+06 - - - 9.4877 1 221125_WJC_METTL3_EV_vs_WT_F10.08987.08987.3 1.74E-06 Aug-92 R.GPVK[136.11]PTGGPGGGGTQTQQQMNQLK[136.11].N "sp|P26196|DDX6_HUMAN,tr|Q8IV96|Q8IV96_HUMAN" 2 2381.2092 1.08 141426 8987 3 2381.208037 794.7437 Probable ATP-dependent RNA helicase DDX6 OS=Homo sapiens OX=9606 GN=DDX6 PE=1 SV=2 10 1975 - 72512.4 - - - -0.506 - 2.252 0.565 - 61.2 1 2 0 -0.0012 24 0 0 0 1.58E+08 1.46E+08 - - - 6.7244 0.9909 221125_WJC_METTL3_EV_vs_WT_F10.08989.08989.2 0.187 Apr-38 K.SSATVTGEPPSYSSGSDSSK[136.11].A "sp|P35658|NU214_HUMAN,tr|A0A494C1F2|A0A494C1F2_HUMAN" 2 1937.8582 2.1 141427 8989 2 1937.859577 969.9364 Nuclear pore complex protein Nup214 OS=Homo sapiens OX=9606 GN=NUP214 PE=1 SV=2 4.37 1975.2 - 80793.7 - - - 0.7312 - 0.962 0.25 - 21.3 1 2 0 0.0014 20 0 0 0 1.05E+07 5.00E+06 - - - 0.7918 1 221125_WJC_METTL3_EV_vs_WT_F10.08994.08994.3 3.52E-07 17/64 R.QGR[166.11]PVVIC[160.03]DK[136.11]EDTETIK[136.11].N "sp|Q06210|GFPT1_HUMAN,tr|A0A6I8PRN4|A0A6I8PRN4_HUMAN" 2 2013.0411 1.38 141431 8994 3 2013.04423 672.021 Glutamine--fructose-6-phosphate aminotransferase [isomerizing] 1 OS=Homo sapiens OX=9606 GN=GFPT1 PE=1 SV=3 4.78 1975.9 - 243202 - - - 1.5494 - 3.597 0.652 - 362.8 1 2 1 0.0031 17 0 0 0 2.02E+07 1.46E+07 - - - 9.0422 0.9999 221125_WJC_METTL3_EV_vs_WT_F10.08995.08995.3 6.94E-10 13/64 R.QGRPVVIC[160.03]DKEDTETIK.N "sp|Q06210|GFPT1_HUMAN,tr|A0A6I8PRN4|A0A6I8PRN4_HUMAN" 2 1987.0044 1.38 141432 8995 3 1987.008783 663.3421 Glutamine--fructose-6-phosphate aminotransferase [isomerizing] 1 OS=Homo sapiens OX=9606 GN=GFPT1 PE=1 SV=3 4.78 1976.1 - 172284 - - - 2.1852 - 2.947 0.574 - 176.7 1 2 1 0.0043 17 0 0 0 2.02E+07 1.46E+07 - - - 7.6687 1 221125_WJC_METTL3_EV_vs_WT_F10.08996.08996.3 7.69E-12 15/92 R.GPVKPTGGPGGGGTQTQQQMNQLK.N "sp|P26196|DDX6_HUMAN,tr|Q8IV96|Q8IV96_HUMAN" 2 2365.1808 1.08 141433 8996 3 2365.187915 789.4009 Probable ATP-dependent RNA helicase DDX6 OS=Homo sapiens OX=9606 GN=DDX6 PE=1 SV=2 10 1976.2 - 157527 - - - 2.9905 - 3.129 0.642 - 282.8 1 2 0 0.0071 24 0 0 0 1.58E+08 1.46E+08 - - - 8.3451 0.8722 221125_WJC_METTL3_EV_vs_WT_F10.08998.08998.2 0.0317 Mar-42 R.GGSGGSHGGGSGFGGESGGSYG.G "sp|P35527|K1C9_HUMAN,tr|K7EQQ3|K7EQQ3_HUMAN" 2 1770.683 - 141435 8998 2 1770.685816 886.3488 "Keratin, type I cytoskeletal 9 OS=Homo sapiens OX=9606 GN=KRT9 PE=1 SV=3" 5.24 1976.5 - 68122.1 - - - 1.5999 - 0.672 0.549 - 13.8 1 1 0 0.0028 22 0 0 0 - - - - - 2.1178 0.9995 221125_WJC_METTL3_EV_vs_WT_F10.09002.09002.4 8.67E-06 14/96 R.QGRPVVIC[160.03]DKEDTETIK.N "sp|Q06210|GFPT1_HUMAN,tr|A0A6I8PRN4|A0A6I8PRN4_HUMAN" 2 1987.0044 1.13 141438 9002 4 1987.009996 497.7584 Glutamine--fructose-6-phosphate aminotransferase [isomerizing] 1 OS=Homo sapiens OX=9606 GN=GFPT1 PE=1 SV=3 4.78 1976.9 - 1.04E+06 - - - 2.7957 - 2.515 0.472 - 151.3 1 2 1 0.0056 17 0 0 0 4.79E+07 4.24E+07 - - - 3.653 1 221125_WJC_METTL3_EV_vs_WT_F10.09003.09003.3 2.01E-07 15/52 R.K[136.11]NPLPPSVGVVDK[136.11]K[136.11].E sp|Q8NC51|PAIRB_HUMAN 1 1500.909 0.74 141439 9003 3 1500.912433 501.3103 Plasminogen activator inhibitor 1 RNA-binding protein OS=Homo sapiens OX=9606 GN=SERBP1 PE=1 SV=2 9.7 1977 - 340771 - - - 2.278 - 2.81 0.576 - 263.2 1 2 0 0.0034 14 0 0 0 9.10E+06 1.23E+07 - - - 7.7066 0.9998 221125_WJC_METTL3_EV_vs_WT_F10.09007.09007.3 0.0346 Jul-68 K.QK[136.11]FNDSEGDDTEETEDYR[166.11].Q "sp|Q9NYF8|BCLF1_HUMAN,tr|E9PKI6|E9PKI6_HUMAN,tr|A0A1W2PQ43|A0A1W2PQ43_HUMAN,tr|E9PK91|E9PK91_HUMAN,tr|E9PK09|E9PK09_HUMAN,tr|E9PQN2|E9PQN2_HUMAN" 6 2194.8893 3.31 141443 9007 3 2194.890448 732.6371 Bcl-2-associated transcription factor 1 OS=Homo sapiens OX=9606 GN=BCLAF1 PE=1 SV=2 3.85 1977.6 - 102542 - - - 0.5003 - 1.819 0.53 - 58.4 1 2 1 0.0011 18 0 0 0 7.13E+06 2.15E+06 - - - 5.9385 0.9998 221125_WJC_METTL3_EV_vs_WT_F10.09014.09014.3 1.98E-06 Nov-72 R.SRGSGGLGGAC[160.03]GGAGFGSR.S "sp|P48668|K2C6C_HUMAN,sp|P04259|K2C6B_HUMAN,sp|P02538|K2C6A_HUMAN" 3 1666.7594 4.72 141448 9014 3 1666.762764 556.5937 "Keratin, type II cytoskeletal 6C OS=Homo sapiens OX=9606 GN=KRT6C PE=1 SV=3" 10.35 1978.4 - 291572 - - - 2.0183 - 2.523 0.545 - 122.9 1 2 1 0.0034 19 0 0 0 1.51E+07 3.20E+06 - - - 6.8889 1 221125_WJC_METTL3_EV_vs_WT_F10.09015.09015.3 4.67E-06 Dec-64 R.KSPSSDSWTC[160.03]ADTSTER.R "sp|Q8N6T3|ARFG1_HUMAN,tr|F8VWH9|F8VWH9_HUMAN,tr|H0YIQ0|H0YIQ0_HUMAN,tr|E5RHH7|E5RHH7_HUMAN" 4 1913.8061 0.38 141449 9015 3 1913.81007 638.9427 ADP-ribosylation factor GTPase-activating protein 1 OS=Homo sapiens OX=9606 GN=ARFGAP1 PE=1 SV=2 4.56 1978.6 - 197611 - - - 2.0561 - 2.196 0.576 - 211 1 2 0 0.0039 17 0 0 0 3.11E+06 8.28E+06 - - - 6.948 0.999 221125_WJC_METTL3_EV_vs_WT_F10.09016.09016.4 0.00222 Nov-72 R.EQVEVVEFHSNK[136.11]K[136.11].R "sp|Q8NDD1|CA131_HUMAN,tr|Q5TBI2|Q5TBI2_HUMAN,tr|Q5TBH9|Q5TBH9_HUMAN" 3 1587.8228 1.1 141450 9016 4 1587.826094 397.963 Uncharacterized protein C1orf131 OS=Homo sapiens OX=9606 GN=C1orf131 PE=1 SV=4 5.5 1978.7 - 193100 - - - 2.0928 - 1.594 0.332 - 54.1 1 2 0 0.0033 13 0 0 0 2.69E+06 2.45E+06 - - - 2.2877 0.9999 221125_WJC_METTL3_EV_vs_WT_F10.09035.09035.3 2.41E-08 16/52 K.KFWETDESSKDGPK.G "sp|Q14671|PUM1_HUMAN,tr|Q5T1Z8|Q5T1Z8_HUMAN,tr|H0YEH2|H0YEH2_HUMAN,tr|Q5T1Z4|Q5T1Z4_HUMAN" 4 1652.7682 2.32 141462 9035 3 1652.770231 551.93 Pumilio homolog 1 OS=Homo sapiens OX=9606 GN=PUM1 PE=1 SV=3 4.78 1981.2 - 287175 - - - 1.2192 - 3.069 0.556 - 319.8 1 2 1 0.002 14 0 0 0 1.21E+07 5.23E+06 - - - 7.7183 0.9998 221125_WJC_METTL3_EV_vs_WT_F10.09037.09037.3 2.87E-06 Aug-52 K.K[136.11]FWETDESSK[136.11]DGPK[136.11].G "sp|Q14671|PUM1_HUMAN,tr|Q5T1Z8|Q5T1Z8_HUMAN,tr|H0YEH2|H0YEH2_HUMAN,tr|Q5T1Z4|Q5T1Z4_HUMAN" 4 1676.8108 2.48 141464 9037 3 1676.809274 559.9442 Pumilio homolog 1 OS=Homo sapiens OX=9606 GN=PUM1 PE=1 SV=3 4.78 1981.5 - 151467 - - - -0.9196 - 1.747 0.525 - 72.2 1 2 1 -0.0015 14 0 0 0 1.33E+07 5.37E+06 - - - 5.8754 0.952 221125_WJC_METTL3_EV_vs_WT_F10.09038.09038.3 0.114 Sep-60 R.RKEEPPQPQLANGALK.V sp|Q9BUV8|RCAF1_HUMAN 1 1774.969 1.73 141465 9038 3 1774.975405 592.6636 Respirasome Complex Assembly Factor 1 OS=Homo sapiens OX=9606 GN=RAB5IF PE=1 SV=1 8.59 1981.6 - 121294 - - - 3.6187 - 1.51 0.296 - 45.1 1 2 1 0.0064 16 0 0 0 1.26E+06 7.28E+05 - - - 2.8957 0.9996 221125_WJC_METTL3_EV_vs_WT_F10.09039.09039.2 1.03E-05 26-Sep R.GNLGAGNGNLQGPR[166.11].H "sp|P43243|MATR3_HUMAN,tr|D6RE02|D6RE02_HUMAN,tr|B3KM87|B3KM87_HUMAN,tr|A8MXP9|A8MXP9_HUMAN,tr|D6RAY2|D6RAY2_HUMAN,tr|D6R991|D6R991_HUMAN,tr|A0A0R4J2E8|A0A0R4J2E8_HUMAN,tr|D6RAM9|D6RAM9_HUMAN,tr|D6RIA2|D6RIA2_HUMAN,tr|H0Y8T4|H0Y8T4_HUMAN,tr|D6REM6|D6REM6_HUMAN,tr|D6RBI2|D6RBI2_HUMAN" 12 1333.6726 1.73 141466 9039 2 1333.674974 667.8436 Matrin-3 OS=Homo sapiens OX=9606 GN=MATR3 PE=1 SV=2 9.75 1981.7 - 91750.4 - - - 1.7576 - 1.877 0.493 - 258.9 1 2 0 0.0023 14 0 0 0 2.98E+06 1.72E+06 - - - 4.2617 0.9997 221125_WJC_METTL3_EV_vs_WT_F10.09049.09049.3 0.00281 Sep-56 R.THTGEKPFAC[160.03]TIC[160.03]GR.A "sp|Q9NSC2|SALL1_HUMAN,tr|H3BSM9|H3BSM9_HUMAN" 2 1733.7978 29.06 141472 9049 3 1733.802039 578.9399 Sal-like protein 1 OS=Homo sapiens OX=9606 GN=SALL1 PE=1 SV=2 7.77 1983.1 - 215283 - - - 2.4686 - 1.952 0.419 - 113.9 1 2 0 0.0043 15 0 0 0 4.40E+06 1.51E+05 - - - 4.9555 0.9965 221125_WJC_METTL3_EV_vs_WT_F10.09067.09067.2 0.0358 14-Jun K.GANPVEIR.R "sp|P10809|CH60_HUMAN,tr|A0A7I2V2X6|A0A7I2V2X6_HUMAN,tr|A0A7I2YQK6|A0A7I2YQK6_HUMAN,tr|A0A7I2V599|A0A7I2V599_HUMAN,tr|E7EXB4|E7EXB4_HUMAN,tr|A0A7I2YQ71|A0A7I2YQ71_HUMAN,tr|E7ESH4|E7ESH4_HUMAN,tr|A0A7I2V5M1|A0A7I2V5M1_HUMAN,tr|A0A7I2V5K3|A0A7I2V5K3_HUMAN,tr|A0A7I2V369|A0A7I2V369_HUMAN" 10 854.461 1.41 141485 9067 2 854.462795 428.2378 "60 kDa heat shock protein, mitochondrial OS=Homo sapiens OX=9606 GN=HSPD1 PE=1 SV=2" 6 1985.3 - 263727 - - - 2.082 - 1.269 0.311 - 169.9 1 2 0 0.0018 8 0 0 0 5.09E+06 3.62E+06 - - - 2.056 1 221125_WJC_METTL3_EV_vs_WT_F10.09069.09069.3 6.05E-09 15/48 K.RTNAENEFVTIKK.D sp|P04264|K2C1_HUMAN 1 1548.826 102.78 141487 9069 3 1548.827732 517.2826 "Keratin, type II cytoskeletal 1 OS=Homo sapiens OX=9606 GN=KRT1 PE=1 SV=6" 8.59 1985.5 - 638231 - - - 1.1144 - 2.881 0.609 - 390.3 1 2 0 0.0017 13 0 0 0 4.36E+07 4.24E+05 - - - 8.1982 0.8027 221125_WJC_METTL3_EV_vs_WT_F10.09076.09076.4 0.495 8/138 R.GPVKPTGGPGGGGTQTQQQMNQLK.N "sp|P26196|DDX6_HUMAN,tr|Q8IV96|Q8IV96_HUMAN" 2 2365.1808 1.88 141492 9076 4 2365.186197 592.3025 Probable ATP-dependent RNA helicase DDX6 OS=Homo sapiens OX=9606 GN=DDX6 PE=1 SV=2 10 1986.4 - 336397 - - - 2.2641 - 1.421 0.141 - 33.4 2 2 0 0.0054 24 0 0 0 4.21E+06 2.24E+06 - - - 0.3351 0.9993 221125_WJC_METTL3_EV_vs_WT_F10.09078.09078.3 4.37E-05 Nov-72 R.SQSSIVPEEEQAANKGEEK.K "sp|Q969G3|SMCE1_HUMAN,tr|A0A2R8Y855|A0A2R8Y855_HUMAN,tr|A0A2R8YES3|A0A2R8YES3_HUMAN,tr|A0A2U3TZQ7|A0A2U3TZQ7_HUMAN,tr|A0A2R8Y7U4|A0A2R8Y7U4_HUMAN,tr|B4DGM3|B4DGM3_HUMAN,tr|A0A2R8Y4T4|A0A2R8Y4T4_HUMAN,tr|A0A2R8Y7I9|A0A2R8Y7I9_HUMAN,tr|A0A2R8Y765|A0A2R8Y765_HUMAN" 9 2058.9706 2.28 141494 9078 3 2058.978021 687.3308 SWI\SNF-related matrix-associated actin-dependent regulator of chromatin subfamily E member 1 OS=Homo sapiens OX=9606 GN=SMARCE1 PE=1 SV=2 4.32 1986.7 - 111460 - - - 3.6246 - 2.169 0.563 - 111.6 1 2 1 0.0075 19 0 0 0 2.13E+07 9.33E+06 - - - 6.717 0.9993 221125_WJC_METTL3_EV_vs_WT_F10.09083.09083.4 0.000155 Nov-78 K.KFWETDESSKDGPK.G "sp|Q14671|PUM1_HUMAN,tr|Q5T1Z8|Q5T1Z8_HUMAN,tr|H0YEH2|H0YEH2_HUMAN,tr|Q5T1Z4|Q5T1Z4_HUMAN" 4 1652.7682 2.64 141497 9083 4 1652.771636 414.1993 Pumilio homolog 1 OS=Homo sapiens OX=9606 GN=PUM1 PE=1 SV=3 4.78 1987.4 - 167603 - - - 2.0693 - 1.711 0.431 - 94.6 1 2 1 0.0034 14 0 0 0 4.06E+06 1.54E+06 - - - 3.1719 0.9998 221125_WJC_METTL3_EV_vs_WT_F10.09088.09088.3 1.26E-07 16/64 R.SSEEPTEKEPPGQLQVK.A "sp|Q9ULV3|CIZ1_HUMAN,tr|Q5SYW2|Q5SYW2_HUMAN,tr|F5H2X7|F5H2X7_HUMAN,tr|H0Y5D5|H0Y5D5_HUMAN,tr|A0A494C0L7|A0A494C0L7_HUMAN,tr|Q9BTG3|Q9BTG3_HUMAN" 6 1881.932 3.72 141500 9088 3 1881.933049 628.3179 Cip1-interacting zinc finger protein OS=Homo sapiens OX=9606 GN=CIZ1 PE=1 SV=2 4.49 1988.1 - 1.17E+06 - - - 0.5643 - 2.657 0.479 - 283.9 1 2 1 0.0011 17 0 0 0 4.68E+07 1.26E+07 - - - 6.3488 0.9999 221125_WJC_METTL3_EV_vs_WT_F10.09089.09089.4 1.06E-07 13/90 K.AIKVEQATKPSFESGR.R "sp|P38159|RBMX_HUMAN,tr|H3BT71|H3BT71_HUMAN,tr|H0Y6E7|H0Y6E7_HUMAN" 3 1746.9264 1.43 141501 9089 4 1746.929115 437.7389 "RNA-binding motif protein, X chromosome OS=Homo sapiens OX=9606 GN=RBMX PE=1 SV=3" 8.63 1988.2 - 692725 - - - 1.5267 - 2.897 0.529 - 90.6 1 2 1 0.0027 16 0 0 0 1.19E+08 8.27E+07 - - - 4.2044 0.9729 221125_WJC_METTL3_EV_vs_WT_F10.09091.09091.2 0.02 Jul-32 R.SSSGQYSGFGQHGSGSD.Q sp|Q5D862|FILA2_HUMAN 1 1643.6448 - 141503 9091 2 1643.646597 822.8297 Filaggrin-2 OS=Homo sapiens OX=9606 GN=FLG2 PE=1 SV=1 5.31 1988.4 - 271132 - - - 1.089 - 1.553 0.45 - 124.5 1 1 0 0.0018 17 0 0 0 - - - - - 3.4464 0.9999 221125_WJC_METTL3_EV_vs_WT_F10.09095.09095.3 7.42E-08 20/60 K.AIK[136.11]VEQATK[136.11]PSFESGR[166.11].R "sp|P38159|RBMX_HUMAN,tr|H3BT71|H3BT71_HUMAN,tr|H0Y6E7|H0Y6E7_HUMAN" 3 1772.9631 1.45 141505 9095 3 1772.965544 591.995 "RNA-binding motif protein, X chromosome OS=Homo sapiens OX=9606 GN=RBMX PE=1 SV=3" 8.63 1989 - 824178 - - - 1.3683 - 3.228 0.594 - 380.8 1 2 1 0.0024 16 0 0 0 7.04E+07 4.86E+07 - - - 8.1687 1 221125_WJC_METTL3_EV_vs_WT_F10.09096.09096.3 1.37E-11 18/68 R.SQTSTADSDLK[136.11]EDGISSR[166.11].K "sp|P27448|MARK3_HUMAN,tr|A0A7I2V3C6|A0A7I2V3C6_HUMAN,tr|A0A7I2V3I9|A0A7I2V3I9_HUMAN,tr|H0YIY6|H0YIY6_HUMAN,tr|A0A7I2V3P5|A0A7I2V3P5_HUMAN,tr|A0A7I2V5G3|A0A7I2V5G3_HUMAN,tr|A0A7I2YQF4|A0A7I2YQF4_HUMAN,tr|A0A7I2YQF7|A0A7I2YQF7_HUMAN,tr|A0A7I2V4K8|A0A7I2V4K8_HUMAN,tr|A0A7I2V3K2|A0A7I2V3K2_HUMAN,tr|A0A7I2V2U9|A0A7I2V2U9_HUMAN,tr|A0A7I2V4G7|A0A7I2V4G7_HUMAN,tr|H0YNV4|H0YNV4_HUMAN,tr|A0A7I2V2N8|A0A7I2V2N8_HUMAN,tr|H0YJI9|H0YJI9_HUMAN,tr|A0A7I2V409|A0A7I2V409_HUMAN,tr|A0A7I2V4T2|A0A7I2V4T2_HUMAN,tr|A0A7I2V549|A0A7I2V549_HUMAN,tr|A0A7I2V3B9|A0A7I2V3B9_HUMAN,tr|A0A7I2V602|A0A7I2V602_HUMAN,tr|A0A7I2V639|A0A7I2V639_HUMAN,tr|A0A7I2V2E3|A0A7I2V2E3_HUMAN,tr|A0A7I2V2I9|A0A7I2V2I9_HUMAN,tr|J3KNR0|J3KNR0_HUMAN,tr|H0YKP9|H0YKP9_HUMAN" 25 1913.8933 0.94 141506 9096 3 1913.896867 638.9717 MAP\microtubule affinity-regulating kinase 3 OS=Homo sapiens OX=9606 GN=MARK3 PE=1 SV=5 4.23 1989.1 - 240199 - - - 1.8569 - 3.855 0.631 - 472.2 1 2 1 0.0036 18 0 0 0 4.23E+06 4.50E+06 - - - 8.9341 0.9927 221125_WJC_METTL3_EV_vs_WT_F10.09100.09100.3 5.21E-08 13/100 R.PAPAVGEAEDKENQQATSGPNQPSVR.R sp|P16989|YBOX3_HUMAN 1 2676.2739 1.29 141510 9100 3 2676.276937 893.0986 Y-box-binding protein 3 OS=Homo sapiens OX=9606 GN=YBX3 PE=1 SV=4 4.41 1989.6 - 205586 - - - 1.1161 - 2.688 0.624 - 174.1 1 1 1 0.003 26 0 0 0 9.67E+06 7.47E+06 - - - 7.771 0.9846 221125_WJC_METTL3_EV_vs_WT_F10.09101.09101.3 3.93E-11 13/100 R.PAPAVGEAEDK[136.11]ENQQATSGPNQPSVR[166.11].R sp|P16989|YBOX3_HUMAN 1 2694.2964 1.3 141511 9101 3 2694.297352 899.1061 Y-box-binding protein 3 OS=Homo sapiens OX=9606 GN=YBX3 PE=1 SV=4 4.41 1989.7 - 173916 - - - 0.3459 - 2.833 0.491 - 144.2 1 1 1 0.0009 26 0 0 0 9.67E+06 7.43E+06 - - - 6.4096 0.9999 221125_WJC_METTL3_EV_vs_WT_F10.09105.09105.3 4.92E-07 20/60 K.AIKVEQATKPSFESGR.R "sp|P38159|RBMX_HUMAN,tr|H3BT71|H3BT71_HUMAN,tr|H0Y6E7|H0Y6E7_HUMAN" 3 1746.9264 1.45 141513 9105 3 1746.929073 583.3161 "RNA-binding motif protein, X chromosome OS=Homo sapiens OX=9606 GN=RBMX PE=1 SV=3" 8.63 1990.3 - 1.77E+06 - - - 1.5026 - 3.735 0.567 - 391.6 1 2 1 0.0026 16 0 0 0 7.04E+07 4.85E+07 - - - 8.2419 0.9999 221125_WJC_METTL3_EV_vs_WT_F10.09106.09106.4 1.69E-05 14/72 K.RTNAENEFVTIKK.D sp|P04264|K2C1_HUMAN 1 1548.826 36.19 141514 9106 4 1548.827276 388.2138 "Keratin, type II cytoskeletal 1 OS=Homo sapiens OX=9606 GN=KRT1 PE=1 SV=6" 8.59 1990.4 - 1.42E+06 - - - 0.82 - 2.436 0.468 - 237.7 1 2 0 0.0013 13 0 0 0 1.60E+07 4.41E+05 - - - 3.6292 1 221125_WJC_METTL3_EV_vs_WT_F10.09109.09109.4 1.34E-11 21/150 R.PAPAVGEAEDKENQQATSGPNQPSVR.R sp|P16989|YBOX3_HUMAN 1 2676.2739 1.18 141517 9109 4 2676.279077 670.0758 Y-box-binding protein 3 OS=Homo sapiens OX=9606 GN=YBX3 PE=1 SV=4 4.41 1990.7 - 260495 - - - 1.9157 - 3.825 0.623 - 245.6 1 1 1 0.0051 26 0 0 0 7.85E+06 6.65E+06 - - - 5.0703 0.9999 221125_WJC_METTL3_EV_vs_WT_F10.09113.09113.4 1.18E-07 10/108 K.R[166.11]TPAPEPEPC[160.03]EASELPAK[136.11]R[166.11].L "sp|Q9ULV3|CIZ1_HUMAN,tr|Q5SYW2|Q5SYW2_HUMAN,tr|F5H2X7|F5H2X7_HUMAN,tr|H0Y5D5|H0Y5D5_HUMAN,tr|A0A494C0L7|A0A494C0L7_HUMAN,tr|Q9BTG3|Q9BTG3_HUMAN" 6 2162.0784 3.82 141521 9113 4 2162.084837 541.5269 Cip1-interacting zinc finger protein OS=Homo sapiens OX=9606 GN=CIZ1 PE=1 SV=2 4.95 1991.3 - 158024 - - - 2.9573 - 2.331 0.559 - 53.3 1 2 0 0.0064 19 0 0 0 1.08E+07 2.84E+06 - - - 4.3761 0.9999 221125_WJC_METTL3_EV_vs_WT_F10.09119.09119.4 1.10E-09 16/90 K.AIK[136.11]VEQATK[136.11]PSFESGR[166.11].R "sp|P38159|RBMX_HUMAN,tr|H3BT71|H3BT71_HUMAN,tr|H0Y6E7|H0Y6E7_HUMAN" 3 1772.9631 1.43 141525 9119 4 1772.965313 444.2481 "RNA-binding motif protein, X chromosome OS=Homo sapiens OX=9606 GN=RBMX PE=1 SV=3" 8.63 1992 - 6.23E+06 - - - 1.238 - 3.132 0.606 - 154.1 1 2 1 0.0022 16 0 0 0 1.18E+08 8.26E+07 - - - 4.9022 1 221125_WJC_METTL3_EV_vs_WT_F10.09120.09120.3 1.48E-08 19/60 R.HGGGGGGFGGGGFGSR.S sp|P35908|K22E_HUMAN 1 1319.5755 108.54 141526 9120 3 1319.577653 440.8658 "Keratin, type II cytoskeletal 2 epidermal OS=Homo sapiens OX=9606 GN=KRT2 PE=1 SV=2" 9.76 1992 - 2.60E+06 - - - 1.5975 - 2.988 0.573 - 310.9 1 2 0 0.0021 16 0 0 0 3.47E+07 3.19E+05 - - - 7.7364 1 221125_WJC_METTL3_EV_vs_WT_F10.09123.09123.4 5.78E-10 22/108 K.RTPAPEPEPC[160.03]EASELPAKR.L "sp|Q9ULV3|CIZ1_HUMAN,tr|Q5SYW2|Q5SYW2_HUMAN,tr|F5H2X7|F5H2X7_HUMAN,tr|H0Y5D5|H0Y5D5_HUMAN,tr|A0A494C0L7|A0A494C0L7_HUMAN,tr|Q9BTG3|Q9BTG3_HUMAN" 6 2134.0477 3.22 141529 9123 4 2134.049237 534.5192 Cip1-interacting zinc finger protein OS=Homo sapiens OX=9606 GN=CIZ1 PE=1 SV=2 4.95 1992.4 - 469932 - - - 0.7188 - 3.406 0.592 - 336.2 1 2 0 0.0015 19 0 0 0 1.10E+07 3.42E+06 - - - 4.7929 1 221125_WJC_METTL3_EV_vs_WT_F10.09124.09124.3 2.16E-10 17/68 R.SQTSTADSDLKEDGISSR.K "sp|P27448|MARK3_HUMAN,tr|A0A7I2V3C6|A0A7I2V3C6_HUMAN,tr|A0A7I2V3I9|A0A7I2V3I9_HUMAN,tr|H0YIY6|H0YIY6_HUMAN,tr|A0A7I2V3P5|A0A7I2V3P5_HUMAN,tr|A0A7I2V5G3|A0A7I2V5G3_HUMAN,tr|A0A7I2YQF4|A0A7I2YQF4_HUMAN,tr|A0A7I2YQF7|A0A7I2YQF7_HUMAN,tr|A0A7I2V4K8|A0A7I2V4K8_HUMAN,tr|A0A7I2V3K2|A0A7I2V3K2_HUMAN,tr|A0A7I2V2U9|A0A7I2V2U9_HUMAN,tr|A0A7I2V4G7|A0A7I2V4G7_HUMAN,tr|H0YNV4|H0YNV4_HUMAN,tr|A0A7I2V2N8|A0A7I2V2N8_HUMAN,tr|H0YJI9|H0YJI9_HUMAN,tr|A0A7I2V409|A0A7I2V409_HUMAN,tr|A0A7I2V4T2|A0A7I2V4T2_HUMAN,tr|A0A7I2V549|A0A7I2V549_HUMAN,tr|A0A7I2V3B9|A0A7I2V3B9_HUMAN,tr|A0A7I2V602|A0A7I2V602_HUMAN,tr|A0A7I2V639|A0A7I2V639_HUMAN,tr|A0A7I2V2E3|A0A7I2V2E3_HUMAN,tr|A0A7I2V2I9|A0A7I2V2I9_HUMAN,tr|J3KNR0|J3KNR0_HUMAN,tr|H0YKP9|H0YKP9_HUMAN" 25 1895.8708 0.94 141530 9124 3 1895.877325 632.9642 MAP\microtubule affinity-regulating kinase 3 OS=Homo sapiens OX=9606 GN=MARK3 PE=1 SV=5 4.23 1992.5 - 339660 - - - 3.419 - 3.72 0.658 - 390 1 2 1 0.0065 18 0 0 0 4.23E+06 4.50E+06 - - - 9.1456 0.9999 221125_WJC_METTL3_EV_vs_WT_F10.09126.09126.4 1.82E-07 14/84 K.DLHDANTDLIGR[166.11]HPK[136.11].Q "sp|P53985|MOT1_HUMAN,tr|Q5T8R3|Q5T8R3_HUMAN,tr|Q5T8R5|Q5T8R5_HUMAN" 3 1718.8819 0.99 141532 9126 4 1718.88501 430.7278 Monocarboxylate transporter 1 OS=Homo sapiens OX=9606 GN=SLC16A1 PE=1 SV=3 5.99 1992.7 - 201248 - - - 1.8087 - 2.816 0.551 - 193 1 2 1 0.0031 15 0 0 0 3.74E+06 3.78E+06 - - - 4.3915 0.9187 221125_WJC_METTL3_EV_vs_WT_F10.09130.09130.3 6.08E-07 Nov-56 A.IKVEQATKPSFESGR.R "sp|P38159|RBMX_HUMAN,tr|H3BT71|H3BT71_HUMAN,tr|H0Y6E7|H0Y6E7_HUMAN" 3 1675.8893 1.94 141536 9130 3 1675.896531 559.6371 "RNA-binding motif protein, X chromosome OS=Homo sapiens OX=9606 GN=RBMX PE=1 SV=3" 8.59 1993.2 - 85194.5 - - - 4.2944 - 2.52 0.559 - 84.7 1 1 1 0.0072 15 0 0 0 1.59E+06 8.20E+05 - - - 7.182 0.9998 221125_WJC_METTL3_EV_vs_WT_F10.09135.09135.4 4.64E-07 13/84 K.DLHDANTDLIGRHPK.Q "sp|P53985|MOT1_HUMAN,tr|Q5T8R3|Q5T8R3_HUMAN,tr|Q5T8R5|Q5T8R5_HUMAN" 3 1700.8594 0.99 141539 9135 4 1700.862256 426.2221 Monocarboxylate transporter 1 OS=Homo sapiens OX=9606 GN=SLC16A1 PE=1 SV=3 5.99 1993.8 - 369035 - - - 1.6609 - 2.254 0.507 - 102.7 1 2 1 0.0028 15 0 0 0 3.72E+06 3.76E+06 - - - 3.9289 1 221125_WJC_METTL3_EV_vs_WT_F10.09136.09136.3 9.29E-06 14/56 R.TPTQTNGSNVPFK[136.11]PR[166.11].G "sp|P78347|GTF2I_HUMAN,tr|A0A494C1K3|A0A494C1K3_HUMAN" 2 1660.8652 1.56 141540 9136 3 1660.867772 554.629 General transcription factor II-I OS=Homo sapiens OX=9606 GN=GTF2I PE=1 SV=2 11 1994 - 344717 - - - 1.5558 - 2.496 0.539 - 141.2 1 2 0 0.0026 15 0 0 0 4.51E+07 2.89E+07 - - - 6.9354 1 221125_WJC_METTL3_EV_vs_WT_F10.09138.09138.3 3.55E-08 16/56 R.TPTQTNGSNVPFKPR.G "sp|P78347|GTF2I_HUMAN,tr|A0A494C1K3|A0A494C1K3_HUMAN" 2 1642.8427 1.56 141542 9138 3 1642.844019 548.6215 General transcription factor II-I OS=Homo sapiens OX=9606 GN=GTF2I PE=1 SV=2 11 1994.1 - 407434 - - - 0.7919 - 3.132 0.584 - 250.4 1 2 0 0.0013 15 0 0 0 4.51E+07 2.89E+07 - - - 8.0297 0.999 221125_WJC_METTL3_EV_vs_WT_F10.09140.09140.4 0.17 Oct-72 R.SSQDHVDEEVFK[136.11]R[166.11].A sp|Q9BRS2|RIOK1_HUMAN 1 1592.755 1.65 141544 9140 4 1592.756229 399.196 Serine\threonine-protein kinase RIO1 OS=Homo sapiens OX=9606 GN=RIOK1 PE=1 SV=2 4.75 1994.4 - 173584 - - - 0.7911 - 1.828 0.301 - 100.6 1 2 0 0.0013 13 0 0 0 1.99E+07 1.21E+07 - - - 2.0692 0.9999 221125_WJC_METTL3_EV_vs_WT_F10.09147.09147.3 1.23E-06 16/44 K.HKDLQQQLVDAK.L sp|P40222|TXLNA_HUMAN 1 1421.7627 1.39 141549 9147 3 1421.764239 474.9282 Alpha-taxilin OS=Homo sapiens OX=9606 GN=TXLNA PE=1 SV=3 6.75 1995.3 - 626386 - - - 1.0986 - 2.771 0.533 - 431.1 1 2 1 0.0016 12 0 0 0 2.42E+07 1.75E+07 - - - 7.3071 0.9998 221125_WJC_METTL3_EV_vs_WT_F10.09148.09148.3 1.74E-05 16/44 K.HK[136.11]DLQQQLVDAK[136.11].L sp|P40222|TXLNA_HUMAN 1 1437.7911 1.4 141550 9148 3 1437.794332 480.271 Alpha-taxilin OS=Homo sapiens OX=9606 GN=TXLNA PE=1 SV=3 6.75 1995.5 - 523812 - - - 2.2639 - 2.8 0.487 - 454.1 1 2 1 0.0033 12 0 0 0 2.44E+07 1.75E+07 - - - 6.8226 1 221125_WJC_METTL3_EV_vs_WT_F10.09149.09149.3 2.43E-11 18/48 R.SSQDHVDEEVFKR.A sp|Q9BRS2|RIOK1_HUMAN 1 1574.7325 1.58 141551 9149 3 1574.735221 525.9181 Serine\threonine-protein kinase RIO1 OS=Homo sapiens OX=9606 GN=RIOK1 PE=1 SV=2 4.75 1995.6 - 424890 - - - 1.7285 - 3.563 0.689 - 616 1 2 0 0.0027 13 0 0 0 2.44E+07 1.55E+07 - - - 9.6659 0.9914 221125_WJC_METTL3_EV_vs_WT_F10.09150.09150.4 6.26E-07 21/150 R.PAPAVGEAEDK[136.11]ENQQATSGPNQPSVR[166.11].R sp|P16989|YBOX3_HUMAN 1 2694.2964 1.18 141552 9150 4 2694.297454 674.5814 Y-box-binding protein 3 OS=Homo sapiens OX=9606 GN=YBX3 PE=1 SV=4 4.41 1995.7 - 383984 - - - 0.3838 - 3.07 0.569 - 197.7 1 1 1 0.001 26 0 0 0 7.85E+06 6.65E+06 - - - 4.5321 1 221125_WJC_METTL3_EV_vs_WT_F10.09151.09151.3 3.41E-13 20/48 R.SSQDHVDEEVFK[136.11]R[166.11].A sp|Q9BRS2|RIOK1_HUMAN 1 1592.755 1.58 141553 9151 3 1592.758794 531.9256 Serine\threonine-protein kinase RIO1 OS=Homo sapiens OX=9606 GN=RIOK1 PE=1 SV=2 4.75 1995.9 - 378502 - - - 2.4015 - 3.872 0.648 - 800.3 1 2 0 0.0038 13 0 0 0 2.44E+07 1.55E+07 - - - 9.434 1 221125_WJC_METTL3_EV_vs_WT_F10.09152.09152.3 4.76E-09 18/76 R.AGNEK[136.11]EEGETADTVGC[160.03]C[160.03]SLR[166.11].V "sp|P11387|TOP1_HUMAN,tr|A0A7P0T852|A0A7P0T852_HUMAN" 2 2199.9491 0.89 141554 9152 3 2199.949704 734.3237 DNA topoisomerase 1 OS=Homo sapiens OX=9606 GN=TOP1 PE=1 SV=2 4.25 1996 - 188222 - - - 0.2605 - 3.255 0.658 - 220 1 2 1 0.0006 20 0 0 0 1.12E+07 1.26E+07 - - - 8.7391 1 221125_WJC_METTL3_EV_vs_WT_F10.09157.09157.4 1.30E-08 18/72 R.SSQDHVDEEVFKR.A sp|Q9BRS2|RIOK1_HUMAN 1 1574.7325 1.64 141557 9157 4 1574.734237 394.6904 Serine\threonine-protein kinase RIO1 OS=Homo sapiens OX=9606 GN=RIOK1 PE=1 SV=2 4.75 1996.7 - 663890 - - - 1.1037 - 3.155 0.649 - 385.1 1 2 0 0.0017 13 0 0 0 1.99E+07 1.21E+07 - - - 5.3004 1 221125_WJC_METTL3_EV_vs_WT_F10.09158.09158.3 1.04E-13 26/76 R.AGNEKEEGETADTVGC[160.03]C[160.03]SLR.V "sp|P11387|TOP1_HUMAN,tr|A0A7P0T852|A0A7P0T852_HUMAN" 2 2181.9267 0.89 141558 9158 3 2181.927213 728.3162 DNA topoisomerase 1 OS=Homo sapiens OX=9606 GN=TOP1 PE=1 SV=2 4.25 1996.9 - 356631 - - - 0.253 - 4.312 0.718 - 605.8 1 2 1 0.0006 20 0 0 0 1.12E+07 1.26E+07 - - - 10.0902 0.9994 221125_WJC_METTL3_EV_vs_WT_F10.09161.09161.3 9.86E-07 Nov-64 R.SSEEPTEK[136.11]EPPGQLQVK[136.11].A "sp|Q9ULV3|CIZ1_HUMAN,tr|Q5SYW2|Q5SYW2_HUMAN,tr|F5H2X7|F5H2X7_HUMAN,tr|H0Y5D5|H0Y5D5_HUMAN,tr|A0A494C0L7|A0A494C0L7_HUMAN,tr|Q9BTG3|Q9BTG3_HUMAN" 6 1897.9604 1.21 141561 9161 3 1897.96178 633.6607 Cip1-interacting zinc finger protein OS=Homo sapiens OX=9606 GN=CIZ1 PE=1 SV=2 4.49 1997.2 - 281411 - - - 0.7339 - 2.341 0.377 - 127.9 1 2 1 0.0014 17 0 0 0 2.90E+07 2.40E+07 - - - 4.8916 1 221125_WJC_METTL3_EV_vs_WT_F10.09162.09162.3 4.96E-07 Dec-72 K.LSTSGNRPPANAETFSC[160.03]NK.L "sp|A6NHR9|SMHD1_HUMAN,tr|J3KTL8|J3KTL8_HUMAN,tr|A0A2R8YE92|A0A2R8YE92_HUMAN" 3 2049.9538 1.5 141562 9162 3 2049.957363 684.3252 Structural maintenance of chromosomes flexible hinge domain-containing protein 1 OS=Homo sapiens OX=9606 GN=SMCHD1 PE=1 SV=2 8.22 1997.4 - 235004 - - - 1.7371 - 2.394 0.556 - 129.5 1 2 0 0.0036 19 0 0 0 1.36E+07 9.07E+06 - - - 6.8826 0.9999 221125_WJC_METTL3_EV_vs_WT_F10.09169.09169.4 0.0438 13/102 K.SLTPAVPVESK[136.11]PDK[136.11]PSGK[136.11].S "sp|P20810|ICAL_HUMAN,tr|A0A6Q8PG72|A0A6Q8PG72_HUMAN,tr|A0A6Q8PFF6|A0A6Q8PFF6_HUMAN,tr|E7EQK6|E7EQK6_HUMAN,tr|F8W7E0|F8W7E0_HUMAN,tr|B7Z574|B7Z574_HUMAN,tr|A0A6Q8PFE5|A0A6Q8PFE5_HUMAN,tr|A0A6Q8PGN6|A0A6Q8PGN6_HUMAN,tr|E7EVY3|E7EVY3_HUMAN,tr|A0A0C4DGB5|A0A0C4DGB5_HUMAN,tr|E9PCH5|E9PCH5_HUMAN,tr|E7ES10|E7ES10_HUMAN,tr|H0Y944|H0Y944_HUMAN,tr|A0A6Q8PGG5|A0A6Q8PGG5_HUMAN,tr|A0A6Q8PH20|A0A6Q8PH20_HUMAN,tr|E9PSG1|E9PSG1_HUMAN,tr|H0YA91|H0YA91_HUMAN" 17 1860.0419 0.74 141567 9169 4 1860.044843 466.0177 Calpastatin OS=Homo sapiens OX=9606 GN=CAST PE=1 SV=4 8.22 1998.3 - 387866 - - - 1.5935 - 2.728 0.407 - 93.2 1 2 0 0.003 18 0 0 0 5.37E+06 7.26E+06 - - - 3.1115 1 221125_WJC_METTL3_EV_vs_WT_F10.09177.09177.3 5.56E-09 19/52 K.HEAFESDLAAHQDR.V "sp|O43707|ACTN4_HUMAN,sp|Q08043|ACTN3_HUMAN,sp|P35609|ACTN2_HUMAN,sp|P12814|ACTN1_HUMAN,tr|A0A804HK61|A0A804HK61_HUMAN,tr|H7C5W8|H7C5W8_HUMAN,tr|A0A804HJU8|A0A804HJU8_HUMAN,tr|A0A804HIN7|A0A804HIN7_HUMAN,tr|A0A494C060|A0A494C060_HUMAN,tr|H9KV75|H9KV75_HUMAN,tr|A0A087WSZ2|A0A087WSZ2_HUMAN,tr|A0A804HLF4|A0A804HLF4_HUMAN,tr|A0A7I2V4Y4|A0A7I2V4Y4_HUMAN,tr|A0A804HII9|A0A804HII9_HUMAN,tr|A0A804HL31|A0A804HL31_HUMAN,tr|A0A494C1A0|A0A494C1A0_HUMAN,tr|F5GXS2|F5GXS2_HUMAN,tr|A0A804HI95|A0A804HI95_HUMAN,tr|A0A804HKE2|A0A804HKE2_HUMAN,tr|A0A804HLD0|A0A804HLD0_HUMAN,tr|H7C144|H7C144_HUMAN" 21 1624.723 1.71 141573 9177 3 1624.724238 542.5816 Alpha-actinin-4 OS=Homo sapiens OX=9606 GN=ACTN4 PE=1 SV=2 4.72 1999.3 - 342640 - - - 0.7638 - 3.721 0.65 - 750.3 1 2 0 0.0012 14 0 0 0 3.89E+06 2.28E+06 - - - 9.2785 0.9995 221125_WJC_METTL3_EV_vs_WT_F10.09184.09184.4 1.46E-05 12/102 K.SLTPAVPVESKPDKPSGK.S "sp|P20810|ICAL_HUMAN,tr|A0A6Q8PG72|A0A6Q8PG72_HUMAN,tr|A0A6Q8PFF6|A0A6Q8PFF6_HUMAN,tr|E7EQK6|E7EQK6_HUMAN,tr|F8W7E0|F8W7E0_HUMAN,tr|B7Z574|B7Z574_HUMAN,tr|A0A6Q8PFE5|A0A6Q8PFE5_HUMAN,tr|A0A6Q8PGN6|A0A6Q8PGN6_HUMAN,tr|E7EVY3|E7EVY3_HUMAN,tr|A0A0C4DGB5|A0A0C4DGB5_HUMAN,tr|E9PCH5|E9PCH5_HUMAN,tr|E7ES10|E7ES10_HUMAN,tr|H0Y944|H0Y944_HUMAN,tr|A0A6Q8PGG5|A0A6Q8PGG5_HUMAN,tr|A0A6Q8PH20|A0A6Q8PH20_HUMAN,tr|E9PSG1|E9PSG1_HUMAN,tr|H0YA91|H0YA91_HUMAN" 17 1835.9993 0.55 141578 9184 4 1836.005601 460.0071 Calpastatin OS=Homo sapiens OX=9606 GN=CAST PE=1 SV=4 8.22 2000.2 - 309015 - - - 3.4434 - 2.147 0.417 - 80.4 1 2 0 0.0063 18 0 0 0 5.81E+06 1.05E+07 - - - 3.1156 0.9994 221125_WJC_METTL3_EV_vs_WT_F10.09185.09185.4 0.00155 13/96 K.VQSLNIENGSEK[136.11]HDLSK[136.11].A "sp|Q15643|TRIPB_HUMAN,tr|H0YJ97|H0YJ97_HUMAN" 2 1912.9825 0.93 141579 9185 4 1912.985335 479.2529 Thyroid receptor-interacting protein 11 OS=Homo sapiens OX=9606 GN=TRIP11 PE=1 SV=3 5.44 2000.3 - 1.09E+06 - - - 1.4715 - 2.713 0.398 - 157 1 2 1 0.0028 17 0 0 0 3.50E+07 3.76E+07 - - - 3.0359 0.9546 221125_WJC_METTL3_EV_vs_WT_F10.09192.09192.4 0.201 Jul-90 R.RSGEPMVSMQAAEEIR[166.11].L "sp|Q9H0B3|IQCN_HUMAN,tr|A0A087WXN0|A0A087WXN0_HUMAN" 2 1799.8534 - 141585 9192 4 1799.84817 450.9706 IQ domain-containing protein N OS=Homo sapiens OX=9606 GN=IQCN PE=1 SV=1 4.79 2001.2 - 132568 - - - -2.8908 - 1.34 0.191 - 27.9 1 2 0 -0.0052 16 0 0 0 - - - - - 0.9901 0.9994 221125_WJC_METTL3_EV_vs_WT_F10.09194.09194.4 1.52E-05 17/96 K.VQSLNIENGSEKHDLSK.A "sp|Q15643|TRIPB_HUMAN,tr|H0YJ97|H0YJ97_HUMAN" 2 1896.9541 0.92 141586 9194 4 1896.959771 475.2458 Thyroid receptor-interacting protein 11 OS=Homo sapiens OX=9606 GN=TRIP11 PE=1 SV=3 5.44 2001.4 - 1.62E+06 - - - 2.979 - 3.121 0.458 - 255 1 2 1 0.0057 17 0 0 0 3.51E+07 3.80E+07 - - - 3.606 0.9999 221125_WJC_METTL3_EV_vs_WT_F10.09202.09202.3 2.58E-08 19/64 K.VQSLNIENGSEK[136.11]HDLSK[136.11].A "sp|Q15643|TRIPB_HUMAN,tr|H0YJ97|H0YJ97_HUMAN" 2 1912.9825 1.24 141593 9202 3 1912.985306 638.6681 Thyroid receptor-interacting protein 11 OS=Homo sapiens OX=9606 GN=TRIP11 PE=1 SV=3 5.44 2002.4 - 848286 - - - 1.4564 - 3.732 0.552 - 481 1 2 1 0.0028 17 0 0 0 2.08E+07 1.68E+07 - - - 8.0205 0.9988 221125_WJC_METTL3_EV_vs_WT_F10.09209.09209.3 0.000263 Aug-52 R.K[136.11]GEITGEVHMPSGK[136.11].T "sp|O75369|FLNB_HUMAN,tr|E7EN95|E7EN95_HUMAN,tr|A0A804HL72|A0A804HL72_HUMAN" 3 1484.7628 0.63 141599 9209 3 1484.768734 495.9282 Filamin-B OS=Homo sapiens OX=9606 GN=FLNB PE=1 SV=2 6.76 2003.3 - 113460 - - - 3.9872 - 1.712 0.432 - 68.3 1 2 0 0.0059 14 0 0 0 1.93E+06 3.05E+06 - - - 4.7836 0.9874 221125_WJC_METTL3_EV_vs_WT_F10.09219.09219.2 0.0196 Mar-38 K.SSATVTGEPPSYSSGSDSSK.A "sp|P35658|NU214_HUMAN,tr|A0A494C1F2|A0A494C1F2_HUMAN" 2 1929.844 4.26 141606 9219 2 1929.850547 965.9293 Nuclear pore complex protein Nup214 OS=Homo sapiens OX=9606 GN=NUP214 PE=1 SV=2 4.37 2004.6 - 74833.6 - - - 3.4132 - 1.02 0.414 - 8 7 2 0 0.0066 20 0 0 0 3.16E+06 7.41E+05 - - - 1.7679 1 221125_WJC_METTL3_EV_vs_WT_F10.09223.09223.3 6.88E-11 14/72 K.AIEPQKEEADENYNSVNTR.M "sp|Q12846|STX4_HUMAN,tr|C9JFM5|C9JFM5_HUMAN" 2 2206.0138 2.37 141609 9223 3 2206.023667 736.3452 Syntaxin-4 OS=Homo sapiens OX=9606 GN=STX4 PE=1 SV=2 4.25 2005.1 - 136934 - - - 4.4642 - 2.87 0.691 - 193.7 1 2 1 0.0098 19 0 0 0 5.75E+06 2.43E+06 - - - 8.8315 0.9996 221125_WJC_METTL3_EV_vs_WT_F10.09229.09229.4 1.46E-05 15/96 K.SQQPLKPQVHTPVATVK.Q "sp|Q6P3W7|SCYL2_HUMAN,tr|A0A0U1RQQ9|A0A0U1RQQ9_HUMAN" 2 1857.0472 1.95 141613 9229 4 1857.054651 465.2691 SCY1-like protein 2 OS=Homo sapiens OX=9606 GN=SCYL2 PE=1 SV=1 10 2006 - 918465 - - - 3.9951 - 2.48 0.455 - 134.9 1 2 0 0.0074 17 0 0 0 2.20E+08 1.13E+08 - - - 3.4996 0.9999 221125_WJC_METTL3_EV_vs_WT_F10.09230.09230.3 4.23E-07 14/64 K.SQQPLKPQVHTPVATVK.Q "sp|Q6P3W7|SCYL2_HUMAN,tr|A0A0U1RQQ9|A0A0U1RQQ9_HUMAN" 2 1857.0472 2.08 141614 9230 3 1857.053866 620.023 SCY1-like protein 2 OS=Homo sapiens OX=9606 GN=SCYL2 PE=1 SV=1 10 2006.1 - 439849 - - - 3.5723 - 2.89 0.567 - 193 1 2 0 0.0066 17 0 0 0 1.20E+08 5.78E+07 - - - 7.5407 0.9913 221125_WJC_METTL3_EV_vs_WT_F10.09231.09231.4 0.0099 12/102 K.LKQESDQLVLNQHPASDK.L sp|P15924|DESP_HUMAN 1 2049.0491 25.17 141615 9231 4 2049.056957 513.2695 Desmoplakin OS=Homo sapiens OX=9606 GN=DSP PE=1 SV=3 5.38 2006.2 - 250602 - - - 3.8428 - 2.24 0.343 - 101.3 1 2 1 0.0079 18 0 0 0 4.23E+06 1.68E+05 - - - 2.4856 0.9999 221125_WJC_METTL3_EV_vs_WT_F10.09232.09232.3 1.02E-06 Nov-64 K.SQQPLK[136.11]PQVHTPVATVK[136.11].Q "sp|Q6P3W7|SCYL2_HUMAN,tr|A0A0U1RQQ9|A0A0U1RQQ9_HUMAN" 2 1873.0756 2.07 141616 9232 3 1873.082431 625.3658 SCY1-like protein 2 OS=Homo sapiens OX=9606 GN=SCYL2 PE=1 SV=1 10 2006.4 - 243629 - - - 3.6299 - 2.582 0.542 - 107.6 1 2 0 0.0068 17 0 0 0 1.19E+08 5.78E+07 - - - 6.9772 0.9997 221125_WJC_METTL3_EV_vs_WT_F10.09238.09238.3 4.22E-11 16/44 K.K[136.11]DEDPENK[136.11]IEFK[136.11].T "sp|Q13123|RED_HUMAN,tr|D6REL4|D6REL4_HUMAN,tr|E7EQZ7|E7EQZ7_HUMAN" 3 1514.7679 1.15 141620 9238 3 1514.77303 505.9299 Protein Red OS=Homo sapiens OX=9606 GN=IK PE=1 SV=3 4.51 2007.2 - 921563 - - - 3.3939 - 3.233 0.56 - 423.8 1 2 1 0.0051 12 0 0 0 4.65E+07 4.03E+07 - - - 8.0345 0.9998 221125_WJC_METTL3_EV_vs_WT_F10.09240.09240.3 3.03E-06 13/72 K.AIEPQK[136.11]EEADENYNSVNTR[166.11].M "sp|Q12846|STX4_HUMAN,tr|C9JFM5|C9JFM5_HUMAN" 2 2224.0363 2.37 141622 9240 3 2224.039181 742.3527 Syntaxin-4 OS=Homo sapiens OX=9606 GN=STX4 PE=1 SV=2 4.25 2007.4 - 276838 - - - 1.3003 - 2.49 0.53 - 166.5 1 2 1 0.0029 19 0 0 0 5.75E+06 2.43E+06 - - - 6.6895 0.9997 221125_WJC_METTL3_EV_vs_WT_F10.09250.09250.3 2.13E-06 Sep-80 K.VLQHYQESDK[136.11]GEELGPGNVQK[136.11].E sp|Q9Y6C9|MTCH2_HUMAN 1 2370.1787 0.98 141630 9250 3 2370.182912 791.0668 Mitochondrial carrier homolog 2 OS=Homo sapiens OX=9606 GN=MTCH2 PE=1 SV=1 4.83 2008.8 - 124353 - - - 1.7969 - 1.712 0.557 - 80.4 1 2 1 0.0043 21 0 0 0 1.90E+06 1.94E+06 - - - 6.0378 0.9997 221125_WJC_METTL3_EV_vs_WT_F10.09255.09255.4 4.90E-05 14/120 K.VLQHYQESDK[136.11]GEELGPGNVQK[136.11].E sp|Q9Y6C9|MTCH2_HUMAN 1 2370.1787 1.07 141633 9255 4 2370.183503 593.5519 Mitochondrial carrier homolog 2 OS=Homo sapiens OX=9606 GN=MTCH2 PE=1 SV=1 4.83 2009.4 - 594439 - - - 2.0463 - 2.838 0.462 - 131.3 1 2 1 0.0049 21 0 0 0 8.41E+06 7.84E+06 - - - 3.5908 0.9999 221125_WJC_METTL3_EV_vs_WT_F10.09256.09256.3 0.000337 13/36 K.EHFAQFGHVR[166.11].R "sp|Q9GZT3|SLIRP_HUMAN,tr|H0YJW7|H0YJW7_HUMAN,tr|A0A087WUN7|A0A087WUN7_HUMAN,tr|G3V2S9|G3V2S9_HUMAN,tr|H0YJU7|H0YJU7_HUMAN,tr|H0YJ07|H0YJ07_HUMAN,tr|H0YJ40|H0YJ40_HUMAN,tr|G3V4X6|G3V4X6_HUMAN" 8 1236.6028 1.35 141634 9256 3 1236.605721 413.2082 "SRA stem-loop-interacting RNA-binding protein, mitochondrial OS=Homo sapiens OX=9606 GN=SLIRP PE=1 SV=1" 7.02 2009.5 - 537555 - - - 2.3945 - 1.959 0.495 - 230.2 1 2 0 0.003 10 0 0 0 1.14E+07 8.40E+06 - - - 6.0217 0.9014 221125_WJC_METTL3_EV_vs_WT_F10.09259.09259.4 2.68E-06 16/66 K.K[136.11]DEDPENK[136.11]IEFK[136.11].T "sp|Q13123|RED_HUMAN,tr|D6REL4|D6REL4_HUMAN,tr|E7EQZ7|E7EQZ7_HUMAN" 3 1514.7679 0.001 141637 9259 4 1516.772727 379.6992 Protein Red OS=Homo sapiens OX=9606 GN=IK PE=1 SV=3 4.51 2009.9 - 221540 - - - 1323.5282 - 2.929 0.562 - 242.5 1 2 1 2.0048 12 0 0 0 0.00E+00 9.80E+05 - - - 3.969 0.9993 221125_WJC_METTL3_EV_vs_WT_F10.09265.09265.3 6.54E-05 Jul-60 K.IHIEENEDR[166.11]DTGLEQR[166.11].H sp|Q96AE7|TTC17_HUMAN 1 1972.9353 1.53 141643 9265 3 1972.933178 658.6524 Tetratricopeptide repeat protein 17 OS=Homo sapiens OX=9606 GN=TTC17 PE=1 SV=1 4.35 2010.7 - 114994 - - - -1.0943 - 1.879 0.424 - 59.6 1 2 1 -0.0022 16 0 0 0 1.69E+06 1.11E+06 - - - 4.885 1 221125_WJC_METTL3_EV_vs_WT_F10.09269.09269.3 5.21E-06 16/36 K.EHFAQFGHVR.R "sp|Q9GZT3|SLIRP_HUMAN,tr|H0YJW7|H0YJW7_HUMAN,tr|A0A087WUN7|A0A087WUN7_HUMAN,tr|G3V2S9|G3V2S9_HUMAN,tr|H0YJU7|H0YJU7_HUMAN,tr|H0YJ07|H0YJ07_HUMAN,tr|H0YJ40|H0YJ40_HUMAN,tr|G3V4X6|G3V4X6_HUMAN" 8 1226.5945 1.35 141645 9269 3 1226.596448 409.8721 "SRA stem-loop-interacting RNA-binding protein, mitochondrial OS=Homo sapiens OX=9606 GN=SLIRP PE=1 SV=1" 7.02 2011.3 - 1.13E+06 - - - 1.5963 - 2.485 0.575 - 473 1 2 0 0.002 10 0 0 0 1.14E+07 8.40E+06 - - - 7.6085 0.9999 221125_WJC_METTL3_EV_vs_WT_F10.09270.09270.4 6.57E-05 15/102 R.TSSAQVEGGVHSLHSYEK[136.11].R "sp|P12268|IMDH2_HUMAN,tr|A0A7I2YQK5|A0A7I2YQK5_HUMAN,tr|H0Y4R1|H0Y4R1_HUMAN,tr|A0A7I2V2T3|A0A7I2V2T3_HUMAN,tr|E7ETK5|E7ETK5_HUMAN" 5 1922.9214 0.74 141646 9270 4 1922.920781 481.7376 Inosine-5'-monophosphate dehydrogenase 2 OS=Homo sapiens OX=9606 GN=IMPDH2 PE=1 SV=2 5.94 2011.3 - 1.02E+06 - - - -0.3058 - 3.341 0.446 - 219 1 2 0 -0.0006 18 0 0 0 1.65E+07 2.23E+07 - - - 3.521 0.999 221125_WJC_METTL3_EV_vs_WT_F10.09271.09271.4 1.91E-06 15/120 K.VLQHYQESDKGEELGPGNVQK.E sp|Q9Y6C9|MTCH2_HUMAN 1 2354.1503 0.96 141647 9271 4 2354.156475 589.5448 Mitochondrial carrier homolog 2 OS=Homo sapiens OX=9606 GN=MTCH2 PE=1 SV=1 4.83 2011.5 - 692398 - - - 2.643 - 3.061 0.412 - 146.4 1 2 1 0.0062 21 0 0 0 7.55E+06 7.84E+06 - - - 3.1802 1 221125_WJC_METTL3_EV_vs_WT_F10.09274.09274.3 1.02E-06 22/68 R.TSSAQVEGGVHSLHSYEK[136.11].R "sp|P12268|IMDH2_HUMAN,tr|A0A7I2YQK5|A0A7I2YQK5_HUMAN,tr|H0Y4R1|H0Y4R1_HUMAN,tr|A0A7I2V2T3|A0A7I2V2T3_HUMAN,tr|E7ETK5|E7ETK5_HUMAN" 5 1922.9214 0.73 141650 9274 3 1922.923607 641.9811 Inosine-5'-monophosphate dehydrogenase 2 OS=Homo sapiens OX=9606 GN=IMPDH2 PE=1 SV=2 5.94 2011.9 - 384084 - - - 1.1639 - 3.807 0.569 - 747.8 1 2 0 0.0022 18 0 0 0 8.39E+06 1.15E+07 - - - 8.212 1 221125_WJC_METTL3_EV_vs_WT_F10.09280.09280.3 1.19E-11 16/76 K.VDNALQSGNSQESVTEQDSK.D "sp|P01834|IGKC_HUMAN,tr|A0A5H1ZRQ3|A0A5H1ZRQ3_HUMAN" 2 2134.9614 999 141654 9280 3 2134.962198 712.6611 Immunoglobulin kappa constant OS=Homo sapiens OX=9606 GN=IGKC PE=1 SV=2 3.92 2012.7 - 768957 - - - 0.3508 - 3.407 0.651 - 345.5 1 2 0 0.0007 20 0 0 0 1.86E+07 0.00E+00 - - - 8.7717 1 221125_WJC_METTL3_EV_vs_WT_F10.09284.09284.4 1.66E-08 15/84 K.EGEQHVDDVSSALKR.F "sp|Q96P48|ARAP1_HUMAN,tr|A0A0A0MSJ2|A0A0A0MSJ2_HUMAN,tr|E7EU13|E7EU13_HUMAN" 3 1668.8067 2.02 141658 9284 4 1668.808448 418.209 "Arf-GAP with Rho-GAP domain, ANK repeat and PH domain-containing protein 1 OS=Homo sapiens OX=9606 GN=ARAP1 PE=1 SV=3" 4.75 2013.2 - 236853 - - - 1.0313 - 2.711 0.58 - 259.3 1 2 0 0.0017 15 0 0 0 2.98E+06 1.48E+06 - - - 4.6307 0.9991 221125_WJC_METTL3_EV_vs_WT_F10.09285.09285.3 0.000123 Nov-56 K.EGEQHVDDVSSALKR.F "sp|Q96P48|ARAP1_HUMAN,tr|A0A0A0MSJ2|A0A0A0MSJ2_HUMAN,tr|E7EU13|E7EU13_HUMAN" 3 1668.8067 1.63 141659 9285 3 1668.814221 557.2762 "Arf-GAP with Rho-GAP domain, ANK repeat and PH domain-containing protein 1 OS=Homo sapiens OX=9606 GN=ARAP1 PE=1 SV=3" 4.75 2013.3 - 229533 - - - 4.4906 - 2.124 0.442 - 157.3 1 2 0 0.0075 15 0 0 0 3.16E+06 1.94E+06 - - - 5.4314 0.9777 221125_WJC_METTL3_EV_vs_WT_F10.09286.09286.4 0.000165 Oct-84 K.EGEQHVDDVSSALK[136.11]R[166.11].F "sp|Q96P48|ARAP1_HUMAN,tr|A0A0A0MSJ2|A0A0A0MSJ2_HUMAN,tr|E7EU13|E7EU13_HUMAN" 3 1686.8292 2.06 141660 9286 4 1686.83163 422.7146 "Arf-GAP with Rho-GAP domain, ANK repeat and PH domain-containing protein 1 OS=Homo sapiens OX=9606 GN=ARAP1 PE=1 SV=3" 4.75 2013.4 - 177729 - - - 1.4424 - 1.839 0.171 - 99.7 1 2 0 0.0024 15 0 0 0 3.10E+06 1.50E+06 - - - 0.9317 1 221125_WJC_METTL3_EV_vs_WT_F10.09291.09291.4 9.66E-09 17/108 R.YGDGGSSFQSTTGHC[160.03]VHMR[166.11].G sp|P55795|HNRH2_HUMAN 1 2092.8719 1.06 141663 9291 4 2092.872942 524.2252 Heterogeneous nuclear ribonucleoprotein H2 OS=Homo sapiens OX=9606 GN=HNRNPH2 PE=1 SV=1 6.91 2014.1 - 1.96E+06 - - - 0.5089 - 3.864 0.684 - 290.8 1 2 0 0.0011 19 0 0 0 4.85E+07 4.58E+07 - - - 5.6365 1 221125_WJC_METTL3_EV_vs_WT_F10.09292.09292.4 4.85E-12 21/108 R.YGDGGSSFQSTTGHC[160.03]VHMR.G sp|P55795|HNRH2_HUMAN 1 2082.8636 1.04 141664 9292 4 2082.865856 521.7232 Heterogeneous nuclear ribonucleoprotein H2 OS=Homo sapiens OX=9606 GN=HNRNPH2 PE=1 SV=1 6.91 2014.2 - 1.73E+06 - - - 1.0798 - 4.024 0.574 - 514.2 1 2 0 0.0022 19 0 0 0 4.77E+07 4.56E+07 - - - 4.6925 0.9999 221125_WJC_METTL3_EV_vs_WT_F10.09293.09293.3 0.000291 Oct-36 R.K[136.11]QDSGHLDLR[166.11].N "sp|Q86U44|MTA70_HUMAN,tr|B4E349|B4E349_HUMAN,tr|F5H6D8|F5H6D8_HUMAN,tr|B4DTN4|B4DTN4_HUMAN" 4 1185.6221 0.01 141665 9293 3 1185.622639 396.2146 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 6.75 2014.3 - 415602 - - - 0.4504 - 1.932 0.418 - 146.3 1 2 0 0.0005 10 0 0 0 5.96E+04 4.73E+06 - - - 5.1234 0.9995 221125_WJC_METTL3_EV_vs_WT_F10.09294.09294.2 0.0012 16-Jul K.AQYEEIAQR.S "sp|P48668|K2C6C_HUMAN,sp|Q01546|K22O_HUMAN,sp|P19013|K2C4_HUMAN,sp|P04259|K2C6B_HUMAN,sp|P35908|K22E_HUMAN,sp|P02538|K2C6A_HUMAN" 6 1106.5356 42.73 141666 9294 2 1106.53448 554.2751 "Keratin, type II cytoskeletal 6C OS=Homo sapiens OX=9606 GN=KRT6C PE=1 SV=3" 4.53 2014.4 - 392430 - - - -1.0456 - 1.649 0.378 - 269.3 1 2 0 -0.0012 9 0 0 0 8.31E+06 1.94E+05 - - - 3.2796 1 221125_WJC_METTL3_EV_vs_WT_F10.09297.09297.2 1.62E-09 Dec-38 K.VDNALQSGNSQESVTEQDSK.D "sp|P01834|IGKC_HUMAN,tr|A0A5H1ZRQ3|A0A5H1ZRQ3_HUMAN" 2 2134.9614 999 141669 9297 2 2134.962607 1068.488 Immunoglobulin kappa constant OS=Homo sapiens OX=9606 GN=IGKC PE=1 SV=2 3.92 2014.8 - 229190 - - - 0.5424 - 2.676 0.721 - 321 1 2 0 0.0012 20 0 0 0 3.37E+06 0.00E+00 - - - 6.7859 1 221125_WJC_METTL3_EV_vs_WT_F10.09300.09300.3 4.95E-14 22/72 R.YGDGGSSFQSTTGHC[160.03]VHMR.G sp|P55795|HNRH2_HUMAN 1 2082.8636 0.95 141671 9300 3 2082.866863 695.2951 Heterogeneous nuclear ribonucleoprotein H2 OS=Homo sapiens OX=9606 GN=HNRNPH2 PE=1 SV=1 6.91 2015.2 - 648564 - - - 1.5632 - 4.54 0.64 - 974.2 1 2 0 0.0033 19 0 0 0 1.19E+07 1.26E+07 - - - 9.3914 0.9982 221125_WJC_METTL3_EV_vs_WT_F10.09302.09302.4 0.0241 Dec-84 R.DLAQYDAAHHEEFKR.Y "sp|Q02818|NUCB1_HUMAN,tr|H7BZI1|H7BZI1_HUMAN,tr|C9JKZ2|C9JKZ2_HUMAN" 3 1828.8493 17.99 141672 9302 4 1828.846919 458.2196 Nucleobindin-1 OS=Homo sapiens OX=9606 GN=NUCB1 PE=1 SV=4 5.31 2015.5 - 705370 - - - -1.28 - 2.262 0.264 - 107 1 2 0 -0.0023 15 0 0 0 1.94E+07 1.08E+06 - - - 1.8153 1 221125_WJC_METTL3_EV_vs_WT_F10.09303.09303.3 8.41E-10 18/52 K.LTHFDHYNQYEQQK.M sp|Q9P2D1|CHD7_HUMAN 1 1849.8384 1.09 141673 9303 3 1849.840503 617.6201 Chromodomain-helicase-DNA-binding protein 7 OS=Homo sapiens OX=9606 GN=CHD7 PE=1 SV=3 5.99 2015.6 - 652505 - - - 1.1579 - 3.221 0.621 - 304.6 1 2 0 0.0021 14 0 0 0 6.13E+06 5.63E+06 - - - 8.5714 0.9914 221125_WJC_METTL3_EV_vs_WT_F10.09304.09304.4 0.109 Jul-72 K.YC[160.03]QR[166.11]PC[160.03]DNLHLC[160.03]K[136.11].L "sp|Q7Z2W4|ZCCHV_HUMAN,tr|C9J6P4|C9J6P4_HUMAN" 2 1780.7926 1 141674 9304 4 1780.792969 446.2054 Zinc finger CCCH-type antiviral protein 1 OS=Homo sapiens OX=9606 GN=ZC3HAV1 PE=1 SV=3 7.96 2015.8 - 528025 - - - 0.1876 - 1.182 0.222 - 25 1 2 0 0.0003 13 0 0 0 6.50E+06 6.52E+06 - - - 1.2202 0.9926 221125_WJC_METTL3_EV_vs_WT_F10.09305.09305.4 0.177 Jul-72 K.YC[160.03]QRPC[160.03]DNLHLC[160.03]K.L "sp|Q7Z2W4|ZCCHV_HUMAN,tr|C9J6P4|C9J6P4_HUMAN" 2 1762.7702 0.77 141675 9305 4 1762.770905 441.6998 Zinc finger CCCH-type antiviral protein 1 OS=Homo sapiens OX=9606 GN=ZC3HAV1 PE=1 SV=3 7.96 2015.9 - 496487 - - - 0.4198 - 1.191 0.228 - 25.4 1 2 0 0.0007 13 0 0 0 7.24E+06 9.39E+06 - - - 1.2751 1 221125_WJC_METTL3_EV_vs_WT_F10.09311.09311.3 1.90E-10 21/72 R.YGDGGSSFQSTTGHC[160.03]VHMR[166.11].G sp|P55795|HNRH2_HUMAN 1 2092.8719 0.95 141679 9311 3 2092.873658 698.6312 Heterogeneous nuclear ribonucleoprotein H2 OS=Homo sapiens OX=9606 GN=HNRNPH2 PE=1 SV=1 6.91 2016.7 - 829779 - - - 0.851 - 4.344 0.746 - 778.1 1 2 0 0.0018 19 0 0 0 1.19E+07 1.26E+07 - - - 10.4652 1 221125_WJC_METTL3_EV_vs_WT_F10.09312.09312.3 2.73E-08 15/60 R.NSATSADEQPHIGNYR.L "sp|Q7KZI7|MARK2_HUMAN,tr|F5H6N2|F5H6N2_HUMAN,tr|A0A0A0MRU9|A0A0A0MRU9_HUMAN,tr|E7ETY4|E7ETY4_HUMAN,tr|F5H4F6|F5H4F6_HUMAN,tr|A0A7I2YQR3|A0A7I2YQR3_HUMAN,tr|E9PC69|E9PC69_HUMAN,tr|A0A7I2V3R3|A0A7I2V3R3_HUMAN,tr|F5H4J8|F5H4J8_HUMAN" 9 1758.7921 1.29 141680 9312 3 1758.794863 587.2713 Serine\threonine-protein kinase MARK2 OS=Homo sapiens OX=9606 GN=MARK2 PE=1 SV=2 5.32 2016.8 - 460166 - - - 1.5488 - 2.952 0.617 - 288.3 1 2 0 0.0027 16 0 0 0 6.10E+06 4.73E+06 - - - 8.1957 0.9999 221125_WJC_METTL3_EV_vs_WT_F10.09318.09318.3 1.74E-05 Aug-48 K.YC[160.03]QR[166.11]PC[160.03]DNLHLC[160.03]K[136.11].L "sp|Q7Z2W4|ZCCHV_HUMAN,tr|C9J6P4|C9J6P4_HUMAN" 2 1780.7926 0.93 141684 9318 3 1780.794684 594.6048 Zinc finger CCCH-type antiviral protein 1 OS=Homo sapiens OX=9606 GN=ZC3HAV1 PE=1 SV=3 7.96 2017.6 - 254760 - - - 1.1506 - 1.905 0.503 - 44.5 1 2 0 0.002 13 0 0 0 2.86E+06 3.07E+06 - - - 5.8948 0.9995 221125_WJC_METTL3_EV_vs_WT_F10.09320.09320.3 6.15E-05 14/48 R.SK[136.11]DK[136.11]LDQVSSEIK[136.11].E "sp|Q53GQ0|DHB12_HUMAN,tr|A0A1B0GVY6|A0A1B0GVY6_HUMAN" 2 1499.8257 1.03 141686 9320 3 1499.830588 500.9492 Very-long-chain 3-oxoacyl-CoA reductase OS=Homo sapiens OX=9606 GN=HSD17B12 PE=1 SV=2 5.84 2017.9 - 519581 - - - 3.2337 - 2.933 0.474 - 158.4 1 2 2 0.0049 13 0 0 0 1.43E+07 1.39E+07 - - - 6.7407 0.9999 221125_WJC_METTL3_EV_vs_WT_F10.09321.09321.3 4.82E-06 Dec-48 R.SKDKLDQVSSEIK.E "sp|Q53GQ0|DHB12_HUMAN,tr|A0A1B0GVY6|A0A1B0GVY6_HUMAN" 2 1475.7831 1.03 141687 9321 3 1475.784086 492.935 Very-long-chain 3-oxoacyl-CoA reductase OS=Homo sapiens OX=9606 GN=HSD17B12 PE=1 SV=2 5.84 2018 - 426676 - - - 0.6424 - 2.43 0.52 - 130.4 1 2 2 0.0009 13 0 0 0 1.43E+07 1.39E+07 - - - 6.7446 0.9997 221125_WJC_METTL3_EV_vs_WT_F10.09329.09329.3 0.000384 16/64 R.SSEEPTEKEPPGQLQVK.A "sp|Q9ULV3|CIZ1_HUMAN,tr|Q5SYW2|Q5SYW2_HUMAN,tr|F5H2X7|F5H2X7_HUMAN,tr|H0Y5D5|H0Y5D5_HUMAN,tr|A0A494C0L7|A0A494C0L7_HUMAN,tr|Q9BTG3|Q9BTG3_HUMAN" 6 1881.932 2.12 141694 9329 3 1881.935494 628.3179 Cip1-interacting zinc finger protein OS=Homo sapiens OX=9606 GN=CIZ1 PE=1 SV=2 4.49 2019 - 541452 - - - 1.8635 - 2.512 0.492 - 272.1 1 2 1 0.0035 17 0 0 0 1.28E+07 6.07E+06 - - - 6.3513 0.9792 221125_WJC_METTL3_EV_vs_WT_F10.09332.09332.3 0.000529 Nov-60 K.KDVDSAYMNKVELQAK.V sp|P12035|K2C3_HUMAN 1 1837.9244 999 141696 9332 3 1837.930847 613.6487 "Keratin, type II cytoskeletal 3 OS=Homo sapiens OX=9606 GN=KRT3 PE=1 SV=3" 6.12 2019.4 - 434612 - - - 3.5083 - 2.274 0.251 - 138.8 1 2 1 0.0064 16 0 0 0 5.45E+06 0.00E+00 - - - 3.4446 0.9995 221125_WJC_METTL3_EV_vs_WT_F10.09333.09333.4 7.84E-06 18/96 R.EIHGAPSNFSSSHLESK[136.11].H "sp|Q5VT06|CE350_HUMAN,tr|E9PIK0|E9PIK0_HUMAN" 2 1833.8737 1.84 141697 9333 4 1833.877813 459.4757 Centrosome-associated protein 350 OS=Homo sapiens OX=9606 GN=CEP350 PE=1 SV=1 6.01 2019.5 - 669634 - - - 2.2477 - 2.863 0.347 - 302.5 1 2 0 0.0041 17 0 0 0 1.42E+07 7.68E+06 - - - 2.6104 1 221125_WJC_METTL3_EV_vs_WT_F10.09334.09334.3 3.86E-08 20/64 R.EIHGAPSNFSSSHLESK.H "sp|Q5VT06|CE350_HUMAN,tr|E9PIK0|E9PIK0_HUMAN" 2 1825.8595 1.54 141698 9334 3 1825.856055 609.6271 Centrosome-associated protein 350 OS=Homo sapiens OX=9606 GN=CEP350 PE=1 SV=1 6.01 2019.6 - 661407 - - - -1.8819 - 3.449 0.591 - 662.7 1 2 0 -0.0034 17 0 0 0 1.00E+07 6.49E+06 - - - 8.2559 1 221125_WJC_METTL3_EV_vs_WT_F10.09335.09335.3 1.62E-08 20/64 R.EIHGAPSNFSSSHLESK[136.11].H "sp|Q5VT06|CE350_HUMAN,tr|E9PIK0|E9PIK0_HUMAN" 2 1833.8737 1.54 141699 9335 3 1833.877118 612.2985 Centrosome-associated protein 350 OS=Homo sapiens OX=9606 GN=CEP350 PE=1 SV=1 6.01 2019.7 - 466529 - - - 1.8687 - 3.803 0.595 - 603.2 1 2 0 0.0034 17 0 0 0 1.00E+07 6.49E+06 - - - 8.5473 0.9923 221125_WJC_METTL3_EV_vs_WT_F10.09339.09339.3 0.065 Aug-68 R.VILDEGHAIRNPNAQQTK.A "sp|Q14527|HLTF_HUMAN,tr|H7C5K0|H7C5K0_HUMAN,tr|A0A0C4DGA6|A0A0C4DGA6_HUMAN" 3 2003.0548 0.01 141703 9339 3 2003.055846 668.6922 Helicase-like transcription factor OS=Homo sapiens OX=9606 GN=HLTF PE=1 SV=2 6.72 2020.2 - 160848 - - - 0.5037 - 1.549 0.31 - 46.9 2 2 1 0.001 18 0 0 0 3.28E+06 3.54E+08 - - - 2.9463 0.9997 221125_WJC_METTL3_EV_vs_WT_F10.09340.09340.4 3.02E-05 Oct-78 R.WPTGDNIHAEHQVR.S "sp|Q14671|PUM1_HUMAN,tr|Q5T1Z8|Q5T1Z8_HUMAN,tr|H0YEH2|H0YEH2_HUMAN,tr|Q5T1Z4|Q5T1Z4_HUMAN,tr|E9PR38|E9PR38_HUMAN" 5 1658.7914 0.78 141704 9340 4 1658.795641 415.7051 Pumilio homolog 1 OS=Homo sapiens OX=9606 GN=PUM1 PE=1 SV=3 5.99 2020.3 - 121963 - - - 2.5856 - 2.113 0.409 - 73.8 1 2 0 0.0043 14 0 0 0 4.62E+06 5.89E+06 - - - 3.057 0.9964 221125_WJC_METTL3_EV_vs_WT_F10.09349.09349.3 1.71E-05 20/68 N.VSVSVSTSHTTISGGGSR.G sp|P04264|K2C1_HUMAN 1 1717.8595 34.26 141711 9349 3 1717.864165 573.6271 "Keratin, type II cytoskeletal 1 OS=Homo sapiens OX=9606 GN=KRT1 PE=1 SV=6" 9.73 2021.4 - 475151 - - - 2.7208 - 3.671 0.568 - 657.5 1 1 0 0.0047 18 0 0 0 6.35E+06 1.85E+05 - - - 8.1096 1 221125_WJC_METTL3_EV_vs_WT_F10.09363.09363.3 8.73E-08 15/68 K.QR[166.11]PLTASLQC[160.03]NSTAQTEK[136.11].V "sp|Q9UFW8|CGBP1_HUMAN,tr|C9JUJ0|C9JUJ0_HUMAN" 2 2050.0232 0.85 141723 9363 3 2050.02615 684.3484 CGG triplet repeat-binding protein 1 OS=Homo sapiens OX=9606 GN=CGGBP1 PE=1 SV=2 8.22 2023.2 - 222947 - - - 1.4283 - 3.177 0.596 - 275.7 1 2 0 0.0029 18 0 0 0 1.71E+07 2.03E+07 - - - 8.0624 0.9998 221125_WJC_METTL3_EV_vs_WT_F10.09366.09366.3 6.17E-05 Nov-52 R.WPTGDNIHAEHQVR.S "sp|Q14671|PUM1_HUMAN,tr|Q5T1Z8|Q5T1Z8_HUMAN,tr|H0YEH2|H0YEH2_HUMAN,tr|Q5T1Z4|Q5T1Z4_HUMAN,tr|E9PR38|E9PR38_HUMAN" 5 1658.7914 0.86 141726 9366 3 1658.796663 553.9377 Pumilio homolog 1 OS=Homo sapiens OX=9606 GN=PUM1 PE=1 SV=3 5.99 2023.6 - 192435 - - - 3.2017 - 2.159 0.484 - 142.7 1 2 0 0.0053 14 0 0 0 2.94E+06 3.40E+06 - - - 5.98 0.9962 221125_WJC_METTL3_EV_vs_WT_F10.09367.09367.4 4.15E-07 15/120 R.LEGGGGPAGGFEDEGEDKKVR.G sp|P50548|ERF_HUMAN 1 2102.9869 1.26 141727 9367 4 2103.001098 526.754 ETS domain-containing transcription factor ERF OS=Homo sapiens OX=9606 GN=ERF PE=1 SV=2 4.36 2023.7 - 176902 - - - 6.7628 - 3.024 0.541 - 164.3 1 2 1 0.0142 21 0 0 0 2.51E+06 1.99E+06 - - - 4.2968 0.9923 221125_WJC_METTL3_EV_vs_WT_F10.09370.09370.4 2.65E-09 18/114 S.SLVSGLNSSASEPAK[136.11]EPAK[136.11]K[136.11].S "sp|Q86U44|MTA70_HUMAN,tr|F5H6D8|F5H6D8_HUMAN,tr|H0YFV6|H0YFV6_HUMAN,tr|B4DTN4|B4DTN4_HUMAN" 4 2023.1012 0 141728 9370 4 2023.100809 506.7826 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 8.22 2024.1 - 1.57E+06 - - - -0.1859 - 3.391 0.578 - 151.9 1 1 1 -0.0004 20 0 0 0 1.52E+07 6.38E+09 - - - 4.6651 1 221125_WJC_METTL3_EV_vs_WT_F10.09372.09372.3 1.73E-09 22/76 S.SLVSGLNSSASEPAK[136.11]EPAK[136.11]K[136.11].S "sp|Q86U44|MTA70_HUMAN,tr|F5H6D8|F5H6D8_HUMAN,tr|H0YFV6|H0YFV6_HUMAN,tr|B4DTN4|B4DTN4_HUMAN" 4 2023.1012 0 141730 9372 3 2023.101057 675.3743 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 8.22 2024.4 - 600406 - - - -0.0633 - 3.704 0.633 - 423.2 1 1 1 -0.0001 20 0 0 0 2.01E+05 3.21E+09 - - - 8.774 0.9993 221125_WJC_METTL3_EV_vs_WT_F10.09373.09373.3 0.00983 Oct-56 K.WK[136.11]PSSGVPSTSDDSR[166.11].R "sp|Q8TBF4|ZCRB1_HUMAN,tr|F8VXY6|F8VXY6_HUMAN,tr|G3V1V1|G3V1V1_HUMAN" 3 1622.7655 0.8 141731 9373 3 1622.769066 541.9291 Zinc finger CCHC-type and RNA-binding motif-containing protein 1 OS=Homo sapiens OX=9606 GN=ZCRB1 PE=1 SV=2 5.96 2024.5 - 331907 - - - 2.1765 - 1.986 0.349 - 66.7 1 2 0 0.0035 15 0 0 0 5.84E+06 7.34E+06 - - - 4.2204 0.9999 221125_WJC_METTL3_EV_vs_WT_F10.09374.09374.3 0.000256 Oct-56 R.DHAPDR[166.11]PFVC[160.03]PDC[160.03]GK[136.11].A sp|Q9BWE0|REPI1_HUMAN 1 1787.7838 1.17 141732 9374 3 1787.784223 596.9352 Replication initiator 1 OS=Homo sapiens OX=9606 GN=REPIN1 PE=1 SV=1 5.3 2024.7 - 292509 - - - 0.212 - 1.949 0.47 - 113.3 1 2 0 0.0004 15 0 0 0 1.24E+07 1.06E+07 - - - 5.5212 0.9987 221125_WJC_METTL3_EV_vs_WT_F10.09379.09379.4 0.000107 19/96 R.EIHGAPSNFSSSHLESK.H "sp|Q5VT06|CE350_HUMAN,tr|E9PIK0|E9PIK0_HUMAN" 2 1825.8595 1.84 141736 9379 4 1825.865839 457.4721 Centrosome-associated protein 350 OS=Homo sapiens OX=9606 GN=CEP350 PE=1 SV=1 6.01 2025.3 - 834768 - - - 3.4767 - 3.265 0.342 - 428.2 1 2 0 0.0063 17 0 0 0 1.42E+07 7.68E+06 - - - 2.6118 0.9996 221125_WJC_METTL3_EV_vs_WT_F10.09381.09381.4 0.000136 17/102 R.VILDEGHAIRNPNAQQTK.A "sp|Q14527|HLTF_HUMAN,tr|H7C5K0|H7C5K0_HUMAN,tr|A0A0C4DGA6|A0A0C4DGA6_HUMAN" 3 2003.0548 0.02 141737 9381 4 2003.057377 501.771 Helicase-like transcription factor OS=Homo sapiens OX=9606 GN=HLTF PE=1 SV=2 6.72 2025.6 - 620693 - - - 1.2681 - 2.994 0.417 - 146 1 2 1 0.0025 18 0 0 0 9.84E+07 5.02E+09 - - - 3.2305 1 221125_WJC_METTL3_EV_vs_WT_F10.09383.09383.3 4.09E-10 19/68 K.QRPLTASLQC[160.03]NSTAQTEK.V "sp|Q9UFW8|CGBP1_HUMAN,tr|C9JUJ0|C9JUJ0_HUMAN" 2 2032.0008 0.83 141739 9383 3 2031.999693 678.3409 CGG triplet repeat-binding protein 1 OS=Homo sapiens OX=9606 GN=CGGBP1 PE=1 SV=2 8.22 2025.9 - 550181 - - - -0.5212 - 3.546 0.637 - 353.4 1 2 0 -0.0011 18 0 0 0 1.69E+07 2.03E+07 - - - 8.7936 0.9999 221125_WJC_METTL3_EV_vs_WT_F10.09384.09384.3 1.98E-05 Oct-56 K.WKPSSGVPSTSDDSR.R "sp|Q8TBF4|ZCRB1_HUMAN,tr|F8VXY6|F8VXY6_HUMAN,tr|G3V1V1|G3V1V1_HUMAN" 3 1604.7431 0.71 141740 9384 3 1604.745097 535.9216 Zinc finger CCHC-type and RNA-binding motif-containing protein 1 OS=Homo sapiens OX=9606 GN=ZCRB1 PE=1 SV=2 5.96 2026 - 452114 - - - 1.2669 - 2.11 0.447 - 111.4 1 2 0 0.002 15 0 0 0 5.84E+06 8.21E+06 - - - 5.4714 0.9984 221125_WJC_METTL3_EV_vs_WT_F10.09396.09396.4 0.0252 Sep-72 R.TDFK[136.11]EEPEPGFK[136.11]R[166.11].L "sp|P47897|SYQ_HUMAN,tr|B4DDN1|B4DDN1_HUMAN,tr|H7C0R3|H7C0R3_HUMAN,tr|A0A0U1RQX5|A0A0U1RQX5_HUMAN,tr|A0A1B0GVU9|A0A1B0GVU9_HUMAN,tr|A0A0U1RRC8|A0A0U1RRC8_HUMAN" 6 1604.8045 1.09 141748 9396 4 1604.805731 402.2084 Glutamine--tRNA ligase OS=Homo sapiens OX=9606 GN=QARS1 PE=1 SV=1 4.87 2027.6 - 262454 - - - 0.7721 - 1.869 0.345 - 70.5 1 2 1 0.0012 13 0 0 0 4.69E+06 4.29E+06 - - - 2.4604 0.9937 221125_WJC_METTL3_EV_vs_WT_F10.09404.09404.3 5.93E-08 22/68 L.VSGLNSSASEPAK[136.11]EPAK[136.11]K[136.11].S "sp|Q86U44|MTA70_HUMAN,tr|F5H6D8|F5H6D8_HUMAN,tr|H0YFV6|H0YFV6_HUMAN,tr|B4DTN4|B4DTN4_HUMAN" 4 1822.9851 0.01 141753 9404 3 1822.982588 608.669 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 8.47 2028.7 - 604794 - - - -1.3736 - 4.035 0.547 - 763 1 1 1 -0.0025 18 0 0 0 1.57E+06 1.29E+08 - - - 8.1115 0.9983 221125_WJC_METTL3_EV_vs_WT_F10.09406.09406.3 5.50E-05 Nov-68 K.SDSGTAAQTSLDIDK[136.11]NEK[136.11].C sp|Q96RL1|UIMC1_HUMAN 1 1894.9091 1.15 141755 9406 3 1894.907699 632.6436 BRCA1-A complex subunit RAP80 OS=Homo sapiens OX=9606 GN=UIMC1 PE=1 SV=2 4.23 2029 - 313176 - - - -0.7288 - 1.635 0.385 - 91.2 1 2 1 -0.0014 18 0 0 0 5.99E+06 5.22E+06 - - - 4.0562 0.9991 221125_WJC_METTL3_EV_vs_WT_F10.09408.09408.4 0.000148 Dec-84 K.DSEADRFSDSHNALR.L sp|Q8TEM1|PO210_HUMAN 1 1718.7608 2.31 141757 9408 4 1718.756327 430.6975 Nuclear pore membrane glycoprotein 210 OS=Homo sapiens OX=9606 GN=NUP210 PE=1 SV=3 4.66 2029.2 - 264734 - - - -2.6251 - 2.133 0.429 - 119.3 1 2 1 -0.0045 15 0 0 0 2.77E+07 1.20E+07 - - - 3.2298 1 221125_WJC_METTL3_EV_vs_WT_F10.09411.09411.3 2.27E-06 13/84 R.ATQLQGDEEPSAPPTSTQAQQK.E "sp|O60231|DHX16_HUMAN,tr|A0A140T947|A0A140T947_HUMAN" 2 2311.0928 0.45 141758 9411 3 2311.09043 771.3715 Pre-mRNA-splicing factor ATP-dependent RNA helicase DHX16 OS=Homo sapiens OX=9606 GN=DHX16 PE=1 SV=2 4.14 2029.6 - 383406 - - - -1.0246 - 2.216 0.548 - 115 1 2 0 -0.0024 22 0 0 0 4.54E+07 1.02E+08 - - - 6.5355 0.9953 221125_WJC_METTL3_EV_vs_WT_F10.09412.09412.3 1.15E-08 22/64 V.SGLNSSASEPAK[136.11]EPAK[136.11]K[136.11].S "sp|Q86U44|MTA70_HUMAN,tr|F5H6D8|F5H6D8_HUMAN,tr|H0YFV6|H0YFV6_HUMAN,tr|B4DTN4|B4DTN4_HUMAN" 4 1723.9167 0.001 141759 9412 3 1723.915322 575.6462 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 8.22 2029.8 - 366538 - - - -0.7866 - 3.754 0.581 - 726.6 1 1 1 -0.0014 17 0 0 0 0.00E+00 4.41E+07 - - - 8.359 0.8282 221125_WJC_METTL3_EV_vs_WT_F10.09414.09414.2 1.54E-06 18-Oct A.SEPAK[136.11]EPAK[136.11]K[136.11].S "sp|Q86U44|MTA70_HUMAN,tr|F5H6D8|F5H6D8_HUMAN,tr|H0YFV6|H0YFV6_HUMAN,tr|B4DTN4|B4DTN4_HUMAN" 4 1107.635 0.001 141761 9414 2 1107.637395 554.8248 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 8.22 2030 - 163847 - - - 2.1406 - 1.799 0.565 - 310 1 1 1 0.0024 10 0 0 0 0.00E+00 2.37E+07 - - - 4.8525 1 221125_WJC_METTL3_EV_vs_WT_F10.09417.09417.3 1.02E-09 17/56 K.DSEADRFSDSHNALR.L sp|Q8TEM1|PO210_HUMAN 1 1718.7608 2.85 141762 9417 3 1718.756593 573.9276 Nuclear pore membrane glycoprotein 210 OS=Homo sapiens OX=9606 GN=NUP210 PE=1 SV=3 4.66 2030.3 - 825462 - - - -2.4704 - 3.857 0.635 - 460.9 1 2 1 -0.0042 15 0 0 0 3.70E+07 1.30E+07 - - - 9.1408 0.9998 221125_WJC_METTL3_EV_vs_WT_F10.09419.09419.4 8.88E-05 15/84 K.DSEADR[166.11]FSDSHNALR[166.11].L sp|Q8TEM1|PO210_HUMAN 1 1738.7774 2.33 141764 9419 4 1738.775743 435.7016 Nuclear pore membrane glycoprotein 210 OS=Homo sapiens OX=9606 GN=NUP210 PE=1 SV=3 4.66 2030.6 - 396515 - - - -0.9409 - 2.309 0.487 - 207.6 1 2 1 -0.0016 15 0 0 0 2.76E+07 1.19E+07 - - - 3.7638 0.9816 221125_WJC_METTL3_EV_vs_WT_F10.09426.09426.3 3.59E-06 14/52 L.NSSASEPAK[136.11]EPAK[136.11]K[136.11].S "sp|Q86U44|MTA70_HUMAN,tr|F5H6D8|F5H6D8_HUMAN,tr|H0YFV6|H0YFV6_HUMAN,tr|B4DTN4|B4DTN4_HUMAN" 4 1466.7791 0.09 141769 9426 3 1466.7763 489.9337 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 8.5 2031.5 - 312176 - - - -1.9239 - 2.604 0.52 - 243.9 1 1 1 -0.0028 14 0 0 0 1.55E+06 1.73E+07 - - - 6.8801 0.9986 221125_WJC_METTL3_EV_vs_WT_F10.09430.09430.4 0.00015 Nov-90 K.KDVDSAYMNKVELQAK.V sp|P12035|K2C3_HUMAN 1 1837.9244 17.77 141771 9430 4 1837.920891 460.4884 "Keratin, type II cytoskeletal 3 OS=Homo sapiens OX=9606 GN=KRT3 PE=1 SV=3" 6.12 2031.9 - 324761 - - - -1.9087 - 1.98 0.368 - 82.8 1 2 1 -0.0035 16 0 0 0 1.35E+07 7.59E+05 - - - 2.6687 0.9846 221125_WJC_METTL3_EV_vs_WT_F10.09431.09431.3 1.68E-06 16/64 K.EQSGTIYLQHADEER[166.11]EK[136.11].T "sp|P37198|NUP62_HUMAN,tr|M0QXN5|M0QXN5_HUMAN" 2 2049.9722 2.17 141772 9431 3 2049.957392 684.3314 Nuclear pore glycoprotein p62 OS=Homo sapiens OX=9606 GN=NUP62 PE=1 SV=3 4.57 2032 - 622052 - - - -7.2391 - 2.832 0.433 - 384.6 1 2 1 -0.0148 17 0 0 0 1.41E+08 6.48E+07 - - - 5.9932 0.9983 221125_WJC_METTL3_EV_vs_WT_F10.09432.09432.4 0.00459 16/96 K.EQSGTIYLQHADEER[166.11]EK[136.11].T "sp|P37198|NUP62_HUMAN,tr|M0QXN5|M0QXN5_HUMAN" 2 2049.9722 2.1 141773 9432 4 2049.966086 513.5003 Nuclear pore glycoprotein p62 OS=Homo sapiens OX=9606 GN=NUP62 PE=1 SV=3 4.57 2032.1 - 1.24E+06 - - - -2.9981 - 2.676 0.393 - 227.3 1 2 1 -0.0061 17 0 0 0 2.74E+08 1.30E+08 - - - 2.9867 1 221125_WJC_METTL3_EV_vs_WT_F10.09434.09434.3 1.76E-08 14/48 K.VDNDENEHQLSLR[166.11].T "sp|P06748|NPM_HUMAN,tr|A0A7I2V4G8|A0A7I2V4G8_HUMAN,tr|A0A7I2YQC0|A0A7I2YQC0_HUMAN,tr|A0A7I2V433|A0A7I2V433_HUMAN,tr|A0A7I2V579|A0A7I2V579_HUMAN,tr|A0A7I2V2X9|A0A7I2V2X9_HUMAN,tr|A0A7I2V3G5|A0A7I2V3G5_HUMAN,tr|A0A7I2V5S2|A0A7I2V5S2_HUMAN,tr|A0A7I2V3U2|A0A7I2V3U2_HUMAN,tr|E5RGW4|E5RGW4_HUMAN" 10 1577.7309 0.88 141775 9434 3 1577.726124 526.9176 Nucleophosmin OS=Homo sapiens OX=9606 GN=NPM1 PE=1 SV=2 4.31 2032.4 - 602060 - - - -3.048 - 3.035 0.59 - 407 1 2 0 -0.0048 13 0 0 0 1.72E+07 1.97E+07 - - - 8.1267 1 221125_WJC_METTL3_EV_vs_WT_F10.09436.09436.2 4.49E-09 18/26 L.NSSASEPAK[136.11]EPAK[136.11]K[136.11].S "sp|Q86U44|MTA70_HUMAN,tr|F5H6D8|F5H6D8_HUMAN,tr|H0YFV6|H0YFV6_HUMAN,tr|B4DTN4|B4DTN4_HUMAN" 4 1466.7791 0.06 141777 9436 2 1466.776135 734.3968 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 8.5 2032.6 - 329023 - - - -2.0364 - 3.051 0.646 - 1073 1 1 1 -0.003 14 0 0 0 1.10E+06 1.95E+07 - - - 6.6106 1 221125_WJC_METTL3_EV_vs_WT_F10.09440.09440.2 1.13E-10 19/38 S.SLVSGLNSSASEPAK[136.11]EPAK[136.11]K[136.11].S "sp|Q86U44|MTA70_HUMAN,tr|F5H6D8|F5H6D8_HUMAN,tr|H0YFV6|H0YFV6_HUMAN,tr|B4DTN4|B4DTN4_HUMAN" 4 2023.1012 0.001 141779 9440 2 2023.09544 1012.5579 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 8.22 2033.2 - 528977 - - - -2.8397 - 3.435 0.697 - 681.7 1 1 1 -0.0057 20 0 0 0 0.00E+00 2.95E+07 - - - 7.2211 1 221125_WJC_METTL3_EV_vs_WT_F10.09450.09450.2 8.36E-09 17/32 V.SGLNSSASEPAK[136.11]EPAK[136.11]K[136.11].S "sp|Q86U44|MTA70_HUMAN,tr|F5H6D8|F5H6D8_HUMAN,tr|H0YFV6|H0YFV6_HUMAN,tr|B4DTN4|B4DTN4_HUMAN" 4 1723.9167 0.001 141783 9450 2 1723.909922 862.9656 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 8.22 2034.4 - 360128 - - - -3.919 - 3.066 0.644 - 703 1 1 1 -0.0068 17 0 0 0 0.00E+00 9.25E+06 - - - 6.55 0.9859 221125_WJC_METTL3_EV_vs_WT_F10.09459.09459.2 1.48E-06 28-Oct R.SDSPVPTAPTSGGPK[136.11].P "sp|Q86U44|MTA70_HUMAN,tr|B4E349|B4E349_HUMAN,tr|F5H6D8|F5H6D8_HUMAN,tr|B4DTN4|B4DTN4_HUMAN" 4 1404.6976 0.36 141788 9459 2 1404.695029 703.3561 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 5.55 2035.6 - 511841 - - - -1.8474 - 2.144 0.531 - 187.9 1 1 0 -0.0026 15 0 0 0 2.82E+07 7.74E+07 - - - 4.8372 0.7853 221125_WJC_METTL3_EV_vs_WT_F10.09478.09478.4 0.000837 22/126 K.SHLVHGSSPGVMGTSVATSASK.L "sp|P35658|NU214_HUMAN,tr|A0A0A0MSW3|A0A0A0MSW3_HUMAN,tr|H0YF36|H0YF36_HUMAN,tr|A0A494C1F2|A0A494C1F2_HUMAN" 4 2096.0321 2.04 141796 9478 4 2097.016458 525.0153 Nuclear pore complex protein Nup214 OS=Homo sapiens OX=9606 GN=NUP214 PE=1 SV=2 8.51 2038.1 - 1.05E+06 - - - 469.6522 - 3.886 0.455 - 324.1 1 2 0 0.9844 22 0 0 0 4.70E+07 2.31E+07 - - - 3.3578 1 221125_WJC_METTL3_EV_vs_WT_F10.09482.09482.3 1.49E-10 16/64 K.QESENSC[160.03]NKEEEPVFTR.Q "sp|Q9Y520|PRC2C_HUMAN,tr|E7EPN9|E7EPN9_HUMAN" 2 2081.896 1 141798 9482 3 2081.891575 694.9726 Protein PRRC2C OS=Homo sapiens OX=9606 GN=PRRC2C PE=1 SV=4 4.33 2038.6 - 2.90E+06 - - - -2.1317 - 3.044 0.74 - 245 1 2 1 -0.0044 17 0 0 0 1.02E+08 1.02E+08 - - - 9.6012 0.9999 221125_WJC_METTL3_EV_vs_WT_F10.09485.09485.3 4.59E-05 Dec-56 R.K[136.11]K[136.11]AEAVVNTVDISER[166.11].E sp|Q8IY81|SPB1_HUMAN 1 1683.9366 0.99 141800 9485 3 1683.93536 562.3195 pre-rRNA 2'-O-ribose RNA methyltransferase FTSJ3 OS=Homo sapiens OX=9606 GN=FTSJ3 PE=1 SV=2 6.18 2038.9 - 229759 - - - -0.718 - 2.157 0.532 - 199.9 1 2 1 -0.0012 15 0 0 0 4.23E+06 4.27E+06 - - - 6.4768 0.9726 221125_WJC_METTL3_EV_vs_WT_F10.09486.09486.3 0.0465 Sep-68 W.ARPVDDGGTEIEGYILEK.R "sp|Q8WZ42|TITIN_HUMAN,tr|A0A0A0MTS7|A0A0A0MTS7_HUMAN,tr|A0A0A0MRA3|A0A0A0MRA3_HUMAN" 3 1960.9742 999 141801 9486 3 1960.973727 654.6653 Titin OS=Homo sapiens OX=9606 GN=TTN PE=1 SV=4 4.18 2039.1 - 501407 - - - -0.2341 - 1.875 0.378 - 87.4 1 1 0 -0.0005 18 0 0 0 1.43E+07 0.00E+00 - - - 4.3195 1 221125_WJC_METTL3_EV_vs_WT_F10.09502.09502.3 4.04E-08 20/56 R.DTNAPESFK[136.11]DTAESR[166.11].S "sp|Q15643|TRIPB_HUMAN,tr|H0YJ97|H0YJ97_HUMAN" 2 1684.7659 1.27 141806 9502 3 1684.763365 562.5959 Thyroid receptor-interacting protein 11 OS=Homo sapiens OX=9606 GN=TRIP11 PE=1 SV=3 4.32 2041.3 - 489145 - - - -1.5213 - 3.454 0.636 - 782.1 1 2 1 -0.0026 15 0 0 0 1.37E+08 1.08E+08 - - - 8.8645 0.9999 221125_WJC_METTL3_EV_vs_WT_F10.09503.09503.3 5.02E-09 16/56 R.DTNAPESFKDTAESR.S "sp|Q15643|TRIPB_HUMAN,tr|H0YJ97|H0YJ97_HUMAN" 2 1666.7435 1.27 141807 9503 3 1666.739149 556.5884 Thyroid receptor-interacting protein 11 OS=Homo sapiens OX=9606 GN=TRIP11 PE=1 SV=3 4.32 2041.5 - 719943 - - - -2.5853 - 3.46 0.586 - 387.7 1 2 1 -0.0043 15 0 0 0 1.37E+08 1.08E+08 - - - 8.3111 1 221125_WJC_METTL3_EV_vs_WT_F10.09504.09504.2 2.24E-09 Oct-40 R.GGSGGSHGGGSGFGGESGGSY.G "sp|P35527|K1C9_HUMAN,tr|K7EQQ3|K7EQQ3_HUMAN" 2 1713.6615 - 141808 9504 2 1713.657183 857.838 "Keratin, type I cytoskeletal 9 OS=Homo sapiens OX=9606 GN=KRT9 PE=1 SV=3" 5.24 2041.6 - 284890 - - - -2.5303 - 2.445 0.698 - 193.1 1 1 0 -0.0043 21 0 0 0 - - - - - 6.3931 0.9999 221125_WJC_METTL3_EV_vs_WT_F10.09508.09508.4 9.35E-06 Nov-78 R.QQANHPYWADTVK[136.11]R[166.11].L "sp|O95985|TOP3B_HUMAN,tr|H7C4B0|H7C4B0_HUMAN,tr|H0Y6W0|H0Y6W0_HUMAN" 3 1730.8608 1.41 141810 9508 4 1730.857259 433.7225 DNA topoisomerase 3-beta-1 OS=Homo sapiens OX=9606 GN=TOP3B PE=1 SV=1 8.6 2042.1 - 264999 - - - -2.0296 - 1.876 0.493 - 95.1 1 2 0 -0.0035 14 0 0 0 5.91E+06 4.18E+06 - - - 3.7451 0.9957 221125_WJC_METTL3_EV_vs_WT_F10.09513.09513.3 0.0295 Nov-52 K.KKIEQQGGFTFENK.G sp|O15397|IPO8_HUMAN 1 1652.8522 1.98 141813 9513 3 1652.847357 551.958 Importin-8 OS=Homo sapiens OX=9606 GN=IPO8 PE=1 SV=2 8.5 2042.8 - 544979 - - - -2.9428 - 1.813 0.379 - 155.7 1 2 1 -0.0049 14 0 0 0 9.96E+06 5.03E+06 - - - 4.3453 1 221125_WJC_METTL3_EV_vs_WT_F10.09515.09515.3 5.64E-06 16/80 K.GSTHPQPGVSPPAAPAAPGPK.D sp|O94925|GLSK_HUMAN 1 1919.9854 1.8 141814 9515 3 1919.982765 641.0024 "Glutaminase kidney isoform, mitochondrial OS=Homo sapiens OX=9606 GN=GLS PE=1 SV=1" 8.76 2043 - 288685 - - - -1.3516 - 3.081 0.54 - 184.3 1 2 0 -0.0026 21 0 0 0 1.14E+07 6.33E+06 - - - 7.2575 1 221125_WJC_METTL3_EV_vs_WT_F10.09522.09522.3 2.91E-09 29/84 K.SHLVHGSSPGVMGTSVATSASK.L "sp|P35658|NU214_HUMAN,tr|A0A0A0MSW3|A0A0A0MSW3_HUMAN,tr|H0YF36|H0YF36_HUMAN,tr|A0A494C1F2|A0A494C1F2_HUMAN" 4 2096.0321 0.7 141819 9522 3 2096.028399 699.6846 Nuclear pore complex protein Nup214 OS=Homo sapiens OX=9606 GN=NUP214 PE=1 SV=2 8.51 2043.9 - 1.30E+06 - - - -1.7428 - 5.139 0.671 - 1261.4 1 2 0 -0.0037 22 0 0 0 4.30E+07 6.11E+07 - - - 9.9007 0.9997 221125_WJC_METTL3_EV_vs_WT_F10.09524.09524.3 7.48E-05 16/68 K.LQTASDESYK[136.11]DPTNIQSK[136.11].H sp|Q13813|SPTN1_HUMAN 1 2039.9982 1.43 141821 9524 3 2039.996705 681.0067 "Spectrin alpha chain, non-erythrocytic 1 OS=Homo sapiens OX=9606 GN=SPTAN1 PE=1 SV=3" 4.56 2044.2 - 359151 - - - -0.7471 - 2.181 0.472 - 129.9 1 2 1 -0.0015 18 0 0 0 4.85E+07 3.38E+07 - - - 5.7437 0.9998 221125_WJC_METTL3_EV_vs_WT_F10.09530.09530.3 0.00082 14/56 K.KITESVAETAQTIKK.S sp|Q96A49|SYAP1_HUMAN 1 1645.9251 1.24 141825 9530 3 1645.926222 549.649 Synapse-associated protein 1 OS=Homo sapiens OX=9606 GN=SYAP1 PE=1 SV=1 8.5 2045 - 354516 - - - 0.7115 - 1.874 0.39 - 122.7 1 2 0 0.0012 15 0 0 0 2.40E+09 1.93E+09 - - - 4.5267 0.9999 221125_WJC_METTL3_EV_vs_WT_F10.09531.09531.3 0.00136 Sep-72 K.NNFGAEPPHQNGEC[160.03]YPNEK[136.11].N "sp|Q92598|HS105_HUMAN,tr|A0A0A0MSM0|A0A0A0MSM0_HUMAN" 2 2208.9374 0.02 141826 9531 3 2208.935211 737.3198 Heat shock protein 105 kDa OS=Homo sapiens OX=9606 GN=HSPH1 PE=1 SV=1 4.75 2045.1 - 284453 - - - -1.0046 - 1.521 0.535 - 34.2 1 2 0 -0.0022 19 0 0 0 1.19E+05 5.04E+06 - - - 5.5344 0.9989 221125_WJC_METTL3_EV_vs_WT_F10.09532.09532.2 4.42E-07 28-Oct R.DTNAPESFK[136.11]DTAESR[166.11].S "sp|Q15643|TRIPB_HUMAN,tr|H0YJ97|H0YJ97_HUMAN" 2 1684.7659 1.51 141827 9532 2 1684.764163 843.3902 Thyroid receptor-interacting protein 11 OS=Homo sapiens OX=9606 GN=TRIP11 PE=1 SV=3 4.32 2045.2 - 185681 - - - -1.0476 - 2.01 0.666 - 273.8 1 2 1 -0.0018 15 0 0 0 9.28E+06 6.16E+06 - - - 5.6759 0.9997 221125_WJC_METTL3_EV_vs_WT_F10.09533.09533.4 0.000234 Sep-78 K.HQAFEAELHANADR[166.11].L "sp|Q13813|SPTN1_HUMAN,tr|A0A0D9SF54|A0A0D9SF54_HUMAN,tr|A0A0D9SGF6|A0A0D9SGF6_HUMAN" 3 1617.7523 2.12 141828 9533 4 1617.754374 405.4454 "Spectrin alpha chain, non-erythrocytic 1 OS=Homo sapiens OX=9606 GN=SPTAN1 PE=1 SV=3" 5.27 2045.4 - 182454 - - - 1.2592 - 1.697 0.377 - 52.7 1 2 0 0.002 14 0 0 0 3.36E+06 1.58E+06 - - - 2.6993 1 221125_WJC_METTL3_EV_vs_WT_F10.09539.09539.2 1.11E-06 13/28 R.DTNAPESFKDTAESR.S "sp|Q15643|TRIPB_HUMAN,tr|H0YJ97|H0YJ97_HUMAN" 2 1666.7435 1.51 141831 9539 2 1666.741896 834.379 Thyroid receptor-interacting protein 11 OS=Homo sapiens OX=9606 GN=TRIP11 PE=1 SV=3 4.32 2046.2 - 204639 - - - -0.9372 - 2.649 0.68 - 521.8 1 2 1 -0.0016 15 0 0 0 9.28E+06 6.16E+06 - - - 6.4581 1 221125_WJC_METTL3_EV_vs_WT_F10.09540.09540.3 5.30E-07 13/68 K.LSPSTSGPHSHDYLPQER.E "sp|Q9HCE1|MOV10_HUMAN,tr|Q5JR04|Q5JR04_HUMAN" 2 2006.9446 1.02 141832 9540 3 2006.944025 669.9888 Helicase MOV-10 OS=Homo sapiens OX=9606 GN=MOV10 PE=1 SV=2 5.99 2046.4 - 178208 - - - -0.295 - 2.346 0.598 - 165.8 1 2 0 -0.0006 18 0 0 0 5.86E+06 5.75E+06 - - - 7.3303 0.9999 221125_WJC_METTL3_EV_vs_WT_F10.09544.09544.3 9.22E-06 14/80 K.GSTHPQPGVSPPAAPAAPGPK[136.11].D sp|O94925|GLSK_HUMAN 1 1927.9996 2.23 141834 9544 3 1927.994453 643.6738 "Glutaminase kidney isoform, mitochondrial OS=Homo sapiens OX=9606 GN=GLS PE=1 SV=1" 8.76 2046.9 - 124846 - - - -2.6489 - 2.342 0.498 - 146.3 1 2 0 -0.0051 21 0 0 0 9.71E+06 4.36E+06 - - - 6.131 1 221125_WJC_METTL3_EV_vs_WT_F10.09546.09546.4 5.66E-07 11/102 K.LSPSTSGPHSHDYLPQER.E "sp|Q9HCE1|MOV10_HUMAN,tr|Q5JR04|Q5JR04_HUMAN" 2 2006.9446 1 141836 9546 4 2006.944484 502.7434 Helicase MOV-10 OS=Homo sapiens OX=9606 GN=MOV10 PE=1 SV=2 5.99 2047.2 - 565713 - - - -0.0663 - 2.739 0.556 - 69.7 1 2 0 -0.0001 18 0 0 0 1.32E+07 1.32E+07 - - - 4.4105 0.9989 221125_WJC_METTL3_EV_vs_WT_F10.09549.09549.4 0.0195 Nov-84 K.AR[166.11]HEVLLISAEQDK[136.11]R[166.11].A "sp|Q00341|VIGLN_HUMAN,tr|A0A024R4E5|A0A024R4E5_HUMAN,tr|C9JIZ1|C9JIZ1_HUMAN,tr|H7C0A4|H7C0A4_HUMAN,tr|H0Y394|H0Y394_HUMAN" 5 1791.995 1.03 141839 9549 4 1791.996396 449.006 Vigilin OS=Homo sapiens OX=9606 GN=HDLBP PE=1 SV=2 6.8 2047.6 - 135854 - - - 0.7952 - 1.962 0.366 - 91.5 1 2 1 0.0014 15 0 0 0 2.06E+06 2.01E+06 - - - 2.6524 0.9999 221125_WJC_METTL3_EV_vs_WT_F10.09554.09554.4 5.09E-06 17/84 K.KITESVAETAQTIKK.S sp|Q96A49|SYAP1_HUMAN 1 1645.9251 1.21 141842 9554 4 1645.924639 412.4885 Synapse-associated protein 1 OS=Homo sapiens OX=9606 GN=SYAP1 PE=1 SV=1 8.5 2048.1 - 538313 - - - -0.2503 - 2.68 0.46 - 137.7 1 2 0 -0.0004 15 0 0 0 2.87E+08 2.37E+08 - - - 3.5825 0.9998 221125_WJC_METTL3_EV_vs_WT_F10.09555.09555.3 4.40E-09 17/68 K.LQTASDESYKDPTNIQSK.H sp|Q13813|SPTN1_HUMAN 1 2023.9698 1.43 141843 9555 3 2023.970882 675.6639 "Spectrin alpha chain, non-erythrocytic 1 OS=Homo sapiens OX=9606 GN=SPTAN1 PE=1 SV=3" 4.56 2048.2 - 2.50E+06 - - - 0.5203 - 2.688 0.458 - 246.6 1 2 1 0.0011 18 0 0 0 4.85E+07 3.38E+07 - - - 6.1082 1 221125_WJC_METTL3_EV_vs_WT_F10.09556.09556.4 7.86E-06 15/84 K.K[136.11]ITESVAETAQTIK[136.11]K[136.11].S sp|Q96A49|SYAP1_HUMAN 1 1669.9677 1.21 141844 9556 4 1669.966913 418.4992 Synapse-associated protein 1 OS=Homo sapiens OX=9606 GN=SYAP1 PE=1 SV=1 8.5 2048.3 - 559226 - - - -0.4419 - 2.67 0.529 - 158.8 1 2 0 -0.0007 15 0 0 0 2.87E+08 2.37E+08 - - - 4.1816 0.9998 221125_WJC_METTL3_EV_vs_WT_F10.09558.09558.4 0.000599 9/114 K.TQKPPQKPAPAVVSVTPAVK.D "sp|Q96CB8|INT12_HUMAN,tr|A0A087WXN4|A0A087WXN4_HUMAN" 2 2042.1888 1.39 141846 9558 4 2042.190093 511.5545 Integrator complex subunit 12 OS=Homo sapiens OX=9606 GN=INTS12 PE=1 SV=1 10.3 2048.6 - 150795 - - - 0.6278 - 2.131 0.378 - 53.8 1 2 0 0.0013 20 0 0 0 2.29E+07 1.65E+07 - - - 2.7687 0.9409 221125_WJC_METTL3_EV_vs_WT_F10.09562.09562.2 0.0209 14-Jul L.KWLDSDAR.N "sp|P34913|HYES_HUMAN,tr|E5RFU2|E5RFU2_HUMAN,tr|E5RFH6|E5RFH6_HUMAN" 3 989.493 192.99 141848 9562 2 989.493444 495.7538 Bifunctional epoxide hydrolase 2 OS=Homo sapiens OX=9606 GN=EPHX2 PE=1 SV=2 5.96 2049.1 - 1.28E+06 - - - 0.4042 - 1.44 0.304 - 290.2 1 1 0 0.0004 8 0 0 0 2.41E+07 1.25E+05 - - - 2.386 1 221125_WJC_METTL3_EV_vs_WT_F10.09564.09564.3 2.05E-11 20/56 K.K[136.11]ITESVAETAQTIK[136.11]K[136.11].S sp|Q96A49|SYAP1_HUMAN 1 1669.9677 1.24 141849 9564 3 1669.969953 557.6632 Synapse-associated protein 1 OS=Homo sapiens OX=9606 GN=SYAP1 PE=1 SV=1 8.5 2049.3 - 6.19E+06 - - - 1.3785 - 3.788 0.696 - 532.1 1 2 0 0.0023 15 0 0 0 2.40E+09 1.93E+09 - - - 9.7743 0.9247 221125_WJC_METTL3_EV_vs_WT_F10.09567.09567.4 0.119 Oct-72 R.DR[166.11]R[166.11]PVHLDQAAFR[166.11].T sp|Q9H0D6|XRN2_HUMAN 1 1609.858 0.96 141852 9567 4 1609.858168 403.4718 5'-3' exoribonuclease 2 OS=Homo sapiens OX=9606 GN=XRN2 PE=1 SV=1 9.52 2049.6 - 215615 - - - 0.1249 - 1.774 0.171 - 103.2 1 2 1 0.0002 13 0 0 0 4.08E+07 4.27E+07 - - - 0.9269 0.9993 221125_WJC_METTL3_EV_vs_WT_F10.09569.09569.3 7.88E-08 14/64 R.SSEEPTEKEPPGQLQVK.A "sp|Q9ULV3|CIZ1_HUMAN,tr|Q5SYW2|Q5SYW2_HUMAN,tr|F5H2X7|F5H2X7_HUMAN,tr|H0Y5D5|H0Y5D5_HUMAN,tr|A0A494C0L7|A0A494C0L7_HUMAN,tr|Q9BTG3|Q9BTG3_HUMAN" 6 1881.932 5.98 141853 9569 3 1881.933156 628.3179 Cip1-interacting zinc finger protein OS=Homo sapiens OX=9606 GN=CIZ1 PE=1 SV=2 4.49 2049.9 - 327378 - - - 0.6212 - 2.755 0.335 - 206.8 1 2 1 0.0012 17 0 0 0 4.97E+07 8.31E+06 - - - 4.8348 0.9998 221125_WJC_METTL3_EV_vs_WT_F10.09572.09572.4 1.52E-05 15/78 K.TSLTVADKIEDQKK.E "sp|P52732|KIF11_HUMAN,tr|A0A7I2V3A9|A0A7I2V3A9_HUMAN" 2 1574.8516 4.84 141855 9572 4 1574.851377 394.7202 Kinesin-like protein KIF11 OS=Homo sapiens OX=9606 GN=KIF11 PE=1 SV=2 5.79 2050.2 - 512255 - - - -0.1111 - 2.688 0.455 - 162.7 1 2 1 -0.0002 14 0 0 0 7.08E+07 1.46E+07 - - - 3.5461 0.9987 221125_WJC_METTL3_EV_vs_WT_F10.09573.09573.4 0.00454 18/120 R.AAPTAVHPVRDYAAQTSPSPK.A "sp|P06576|ATPB_HUMAN,tr|F8W0P7|F8W0P7_HUMAN" 2 2163.1073 3.33 141856 9573 4 2163.109344 541.7841 "ATP synthase subunit beta, mitochondrial OS=Homo sapiens OX=9606 GN=ATP5F1B PE=1 SV=3" 8.64 2050.3 - 368819 - - - 0.9607 - 2.64 0.348 - 56.2 1 2 1 0.0021 21 0 0 0 1.33E+07 3.98E+06 - - - 2.5754 1 221125_WJC_METTL3_EV_vs_WT_F10.09575.09575.3 3.45E-08 16/68 K.KAEADGSGQQNVGMNLTR.T "sp|P78364|PHC1_HUMAN,tr|J3KQH6|J3KQH6_HUMAN" 2 1874.8905 3.29 141858 9575 3 1874.892712 625.9708 Polyhomeotic-like protein 1 OS=Homo sapiens OX=9606 GN=PHC1 PE=1 SV=3 6.07 2050.6 - 299903 - - - 1.1942 - 2.88 0.516 - 254.4 1 2 0 0.0022 18 0 0 0 1.32E+07 4.02E+06 - - - 6.9263 0.9996 221125_WJC_METTL3_EV_vs_WT_F10.09577.09577.4 0.00291 14/78 K.TSLTVADK[136.11]IEDQK[136.11]K[136.11].E "sp|P52732|KIF11_HUMAN,tr|A0A7I2V3A9|A0A7I2V3A9_HUMAN" 2 1598.8942 4.85 141860 9577 4 1598.894243 400.7308 Kinesin-like protein KIF11 OS=Homo sapiens OX=9606 GN=KIF11 PE=1 SV=2 5.79 2050.9 - 254319 - - - 0.0569 - 2.408 0.417 - 129.3 1 2 1 0.0001 14 0 0 0 7.07E+07 1.46E+07 - - - 3.1754 1 221125_WJC_METTL3_EV_vs_WT_F10.09580.09580.3 1.63E-05 Aug-68 K.K[136.11]AEADGSGQQNVGMNLTR[166.11].T "sp|P78364|PHC1_HUMAN,tr|J3KQH6|J3KQH6_HUMAN" 2 1892.9129 3.24 141863 9580 3 1892.914471 631.9783 Polyhomeotic-like protein 1 OS=Homo sapiens OX=9606 GN=PHC1 PE=1 SV=3 6.07 2051.2 - 157967 - - - 0.8072 - 1.812 0.544 - 61.4 1 2 0 0.0015 18 0 0 0 1.33E+07 4.11E+06 - - - 6.0848 0.9999 221125_WJC_METTL3_EV_vs_WT_F10.09583.09583.3 6.51E-09 18/52 K.TSLTVADKIEDQKK.E "sp|P52732|KIF11_HUMAN,tr|A0A7I2V3A9|A0A7I2V3A9_HUMAN" 2 1574.8516 5.38 141864 9583 3 1574.852841 525.9578 Kinesin-like protein KIF11 OS=Homo sapiens OX=9606 GN=KIF11 PE=1 SV=2 5.79 2051.7 - 2.86E+06 - - - 0.8185 - 3.753 0.498 - 601.4 1 2 1 0.0013 14 0 0 0 1.15E+08 2.13E+07 - - - 7.6066 0.9998 221125_WJC_METTL3_EV_vs_WT_F10.09584.09584.3 1.75E-06 16/52 K.TSLTVADK[136.11]IEDQK[136.11]K[136.11].E "sp|P52732|KIF11_HUMAN,tr|A0A7I2V3A9|A0A7I2V3A9_HUMAN" 2 1598.8942 5.38 141865 9584 3 1598.897657 533.972 Kinesin-like protein KIF11 OS=Homo sapiens OX=9606 GN=KIF11 PE=1 SV=2 5.79 2051.8 - 700095 - - - 2.1921 - 2.926 0.51 - 395.5 1 2 1 0.0035 14 0 0 0 1.15E+08 2.13E+07 - - - 7.0782 0.9999 221125_WJC_METTL3_EV_vs_WT_F10.09586.09586.4 1.49E-07 13/114 K.TQK[136.11]PPQK[136.11]PAPAVVSVTPAVK[136.11].D "sp|Q96CB8|INT12_HUMAN,tr|A0A087WXN4|A0A087WXN4_HUMAN" 2 2066.2314 1.39 141867 9586 4 2066.238685 517.5651 Integrator complex subunit 12 OS=Homo sapiens OX=9606 GN=INTS12 PE=1 SV=1 10.3 2052 - 325923 - - - 3.5204 - 2.296 0.583 - 131 1 2 0 0.0073 20 0 0 0 2.29E+07 1.65E+07 - - - 4.5763 0.9998 221125_WJC_METTL3_EV_vs_WT_F10.09588.09588.3 0.000639 Nov-68 R.KDVGRPNFEEGGPTSVGR.K "sp|Q6Y7W6|GGYF2_HUMAN,tr|E7ESB6|E7ESB6_HUMAN" 2 1900.9391 5.63 141869 9588 3 1900.938816 634.6537 GRB10-interacting GYF protein 2 OS=Homo sapiens OX=9606 GN=GIGYF2 PE=1 SV=1 6.18 2052.3 - 237762 - - - -0.1694 - 2.049 0.373 - 84.3 1 2 0 -0.0003 18 0 0 0 1.52E+07 2.70E+06 - - - 4.4848 0.9962 221125_WJC_METTL3_EV_vs_WT_F10.09589.09589.3 0.00734 Sep-48 R.FREDHPDLIQNAK.K "sp|P17480|UBF1_HUMAN,tr|E9PKP7|E9PKP7_HUMAN" 2 1581.79 0.85 141870 9589 3 1581.789921 528.2706 Nucleolar transcription factor 1 OS=Homo sapiens OX=9606 GN=UBTF PE=1 SV=1 5.38 2052.4 - 220961 - - - -0.0215 - 1.648 0.319 - 86.9 1 2 1 0 13 0 0 0 1.37E+06 1.62E+06 - - - 3.451 0.9977 221125_WJC_METTL3_EV_vs_WT_F10.09590.09590.4 0.00457 12/120 R.AAPTAVHPVR[166.11]DYAAQTSPSPK[136.11].A "sp|P06576|ATPB_HUMAN,tr|F8W0P7|F8W0P7_HUMAN" 2 2181.1297 2.66 141871 9590 4 2181.132249 546.2897 "ATP synthase subunit beta, mitochondrial OS=Homo sapiens OX=9606 GN=ATP5F1B PE=1 SV=3" 8.64 2052.6 - 207629 - - - 1.1522 - 2.532 0.317 - 91.5 1 2 1 0.0025 21 0 0 0 7.43E+06 2.79E+06 - - - 2.2916 0.9999 221125_WJC_METTL3_EV_vs_WT_F10.09591.09591.2 3.16E-07 28-Nov K.K[136.11]ITESVAETAQTIK[136.11]K[136.11].S sp|Q96A49|SYAP1_HUMAN 1 1669.9677 1.27 141872 9591 2 1669.965101 835.9911 Synapse-associated protein 1 OS=Homo sapiens OX=9606 GN=SYAP1 PE=1 SV=1 8.5 2052.7 - 158098 - - - -1.527 - 2.346 0.597 - 253.2 1 2 0 -0.0026 15 0 0 0 4.32E+07 3.40E+07 - - - 5.5461 0.9999 221125_WJC_METTL3_EV_vs_WT_F10.09601.09601.2 2.30E-06 16/28 K.KITESVAETAQTIKK.S sp|Q96A49|SYAP1_HUMAN 1 1645.9251 1.27 141880 9601 2 1645.925462 823.9698 Synapse-associated protein 1 OS=Homo sapiens OX=9606 GN=SYAP1 PE=1 SV=1 8.5 2053.8 - 240230 - - - 0.2497 - 3.294 0.48 - 524.5 1 2 0 0.0004 15 0 0 0 4.32E+07 3.40E+07 - - - 5.517 1 221125_WJC_METTL3_EV_vs_WT_F10.09602.09602.3 1.44E-06 Nov-68 K.LSPSTSGPHSHDYLPQER[166.11].E "sp|Q9HCE1|MOV10_HUMAN,tr|Q5JR04|Q5JR04_HUMAN" 2 2016.9529 1.02 141881 9602 3 2016.956022 673.3249 Helicase MOV-10 OS=Homo sapiens OX=9606 GN=MOV10 PE=1 SV=2 5.99 2053.9 - 226021 - - - 1.5543 - 2.332 0.569 - 163.7 1 2 0 0.0031 18 0 0 0 5.86E+06 5.75E+06 - - - 6.9914 0.9995 221125_WJC_METTL3_EV_vs_WT_F10.09611.09611.3 0.00128 14/76 R.QEQQEGPVGPAPSR[166.11]PALQEK[136.11].Q sp|Q8TDD1|DDX54_HUMAN 1 2163.1039 0.79 141889 9611 3 2163.101857 722.0419 ATP-dependent RNA helicase DDX54 OS=Homo sapiens OX=9606 GN=DDX54 PE=1 SV=2 4.79 2054.9 - 533625 - - - -0.9514 - 2.758 0.252 - 261.1 1 2 0 -0.0021 20 0 0 0 1.89E+07 2.38E+07 - - - 3.8102 1 221125_WJC_METTL3_EV_vs_WT_F10.09612.09612.3 5.77E-11 25/92 R.RAASAATAAPTATPAAQESGTIPK.K "sp|O00116|ADAS_HUMAN,tr|A0A7P0TA54|A0A7P0TA54_HUMAN,tr|A0A2R8YEL0|A0A2R8YEL0_HUMAN,tr|B8ZZ81|B8ZZ81_HUMAN,tr|A0A7P0T857|A0A7P0T857_HUMAN,tr|A0A7P0T9C9|A0A7P0T9C9_HUMAN,tr|A0A7P0TAL3|A0A7P0TAL3_HUMAN,tr|A0A1B0GWA2|A0A1B0GWA2_HUMAN,tr|A0A7P0T984|A0A7P0T984_HUMAN,tr|A0A7P0T8Q7|A0A7P0T8Q7_HUMAN" 10 2238.1604 1.34 141890 9612 3 2238.159802 747.0608 "Alkyldihydroxyacetonephosphate synthase, peroxisomal OS=Homo sapiens OX=9606 GN=AGPS PE=1 SV=1" 8.75 2055.1 - 525772 - - - -0.2779 - 3.817 0.561 - 484.4 1 2 0 -0.0006 24 0 0 0 1.21E+07 9.04E+06 - - - 7.9055 1 221125_WJC_METTL3_EV_vs_WT_F10.09619.09619.3 0.000153 13/44 R.TLVAVKPDGVQR.R "sp|O00746|NDKM_HUMAN,tr|Q4TT34|Q4TT34_HUMAN,tr|A0A087WVT9|A0A087WVT9_HUMAN,tr|H0Y6J0|H0Y6J0_HUMAN,tr|F2Z2X0|F2Z2X0_HUMAN" 5 1281.7405 2.17 141895 9619 3 1281.73903 428.2541 "Nucleoside diphosphate kinase, mitochondrial OS=Homo sapiens OX=9606 GN=NME4 PE=1 SV=1" 8.41 2055.8 - 760015 - - - -1.1352 - 2.201 0.475 - 199.8 1 2 0 -0.0015 12 0 0 0 8.15E+06 3.76E+06 - - - 6.0221 0.9925 221125_WJC_METTL3_EV_vs_WT_F10.09620.09620.4 0.184 13/102 R.KDVGRPNFEEGGPTSVGR.K "sp|Q6Y7W6|GGYF2_HUMAN,tr|E7ESB6|E7ESB6_HUMAN" 2 1900.9391 2.65 141896 9620 4 1900.936076 476.2421 GRB10-interacting GYF protein 2 OS=Homo sapiens OX=9606 GN=GIGYF2 PE=1 SV=1 6.18 2055.9 - 609944 - - - -1.6108 - 1.878 0.215 - 94.8 1 2 0 -0.0031 18 0 0 0 1.79E+07 6.77E+06 - - - 1.3124 1 221125_WJC_METTL3_EV_vs_WT_F10.09622.09622.3 9.16E-05 20/92 R.R[166.11]AASAATAAPTATPAAQESGTIPK[136.11].K "sp|O00116|ADAS_HUMAN,tr|A0A7P0TA54|A0A7P0TA54_HUMAN,tr|A0A2R8YEL0|A0A2R8YEL0_HUMAN,tr|B8ZZ81|B8ZZ81_HUMAN,tr|A0A7P0T857|A0A7P0T857_HUMAN,tr|A0A7P0T9C9|A0A7P0T9C9_HUMAN,tr|A0A7P0TAL3|A0A7P0TAL3_HUMAN,tr|A0A1B0GWA2|A0A1B0GWA2_HUMAN,tr|A0A7P0T984|A0A7P0T984_HUMAN,tr|A0A7P0T8Q7|A0A7P0T8Q7_HUMAN" 10 2256.1829 1.34 141898 9622 3 2256.180237 753.0682 "Alkyldihydroxyacetonephosphate synthase, peroxisomal OS=Homo sapiens OX=9606 GN=AGPS PE=1 SV=1" 8.75 2056.2 - 472193 - - - -1.1777 - 3.61 0.551 - 266.7 1 2 0 -0.0027 24 0 0 0 1.21E+07 9.04E+06 - - - 7.6639 0.9999 221125_WJC_METTL3_EV_vs_WT_F10.09623.09623.4 1.15E-06 11/102 K.LSPSTSGPHSHDYLPQER[166.11].E "sp|Q9HCE1|MOV10_HUMAN,tr|Q5JR04|Q5JR04_HUMAN" 2 2016.9529 1.05 141899 9623 4 2016.951803 505.2455 Helicase MOV-10 OS=Homo sapiens OX=9606 GN=MOV10 PE=1 SV=2 5.99 2056.3 - 472015 - - - -0.5374 - 2.829 0.458 - 69.1 1 2 0 -0.0011 18 0 0 0 9.15E+06 8.73E+06 - - - 3.5684 0.9995 221125_WJC_METTL3_EV_vs_WT_F10.09624.09624.3 0.00523 Nov-44 R.TLVAVK[136.11]PDGVQR[166.11].R "sp|O00746|NDKM_HUMAN,tr|Q4TT34|Q4TT34_HUMAN,tr|A0A087WVT9|A0A087WVT9_HUMAN,tr|H0Y6J0|H0Y6J0_HUMAN,tr|F2Z2X0|F2Z2X0_HUMAN" 5 1299.763 2.17 141900 9624 3 1299.759715 434.2616 "Nucleoside diphosphate kinase, mitochondrial OS=Homo sapiens OX=9606 GN=NME4 PE=1 SV=1" 8.41 2056.4 - 223463 - - - -2.4928 - 2.178 0.346 - 138.4 1 2 0 -0.0032 12 0 0 0 8.15E+06 3.76E+06 - - - 4.5543 0.9561 221125_WJC_METTL3_EV_vs_WT_F10.09628.09628.4 9.13E-05 10/114 S.SLVSGLNSSASEPAK[136.11]EPAK[136.11]K[136.11].S "sp|Q86U44|MTA70_HUMAN,tr|F5H6D8|F5H6D8_HUMAN,tr|H0YFV6|H0YFV6_HUMAN,tr|B4DTN4|B4DTN4_HUMAN" 4 2023.1012 0.08 141902 9628 4 2023.099166 506.7826 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 8.22 2057 - 231439 - - - -0.998 - 2.052 0.431 - 40.5 1 1 1 -0.002 20 0 0 0 5.37E+05 6.55E+06 - - - 3.2172 1 221125_WJC_METTL3_EV_vs_WT_F10.09631.09631.3 2.44E-08 17/76 R.QEQQEGPVGPAPSRPALQEK.Q sp|Q8TDD1|DDX54_HUMAN 1 2145.0814 0.8 141905 9631 3 2145.079411 716.0344 ATP-dependent RNA helicase DDX54 OS=Homo sapiens OX=9606 GN=DDX54 PE=1 SV=2 4.79 2057.4 - 527235 - - - -0.9482 - 3.166 0.577 - 315.3 1 2 0 -0.002 20 0 0 0 1.89E+07 2.35E+07 - - - 7.7683 1 221125_WJC_METTL3_EV_vs_WT_F10.09632.09632.3 1.35E-07 15/96 K.VASTLTEEGGGGGGGGGSVAPKPPR.G "sp|Q8TF68|ZN384_HUMAN,tr|F5H105|F5H105_HUMAN,tr|F5H8L7|F5H8L7_HUMAN,tr|A0A804HJE2|A0A804HJE2_HUMAN,tr|E9PHB3|E9PHB3_HUMAN" 5 2194.0978 1.37 141906 9632 3 2194.099575 732.3732 Zinc finger protein 384 OS=Homo sapiens OX=9606 GN=ZNF384 PE=1 SV=2 6.11 2057.5 - 252726 - - - 0.7981 - 2.996 0.597 - 196 1 2 0 0.0018 25 0 0 0 5.56E+06 4.07E+06 - - - 7.7199 1 221125_WJC_METTL3_EV_vs_WT_F10.09635.09635.3 3.72E-08 18/56 K.K[136.11]ITESVAETAQTIKK[136.11].S sp|Q96A49|SYAP1_HUMAN 1 1661.9535 - 141907 9635 3 1661.952481 554.9918 Synapse-associated protein 1 OS=Homo sapiens OX=9606 GN=SYAP1 PE=1 SV=1 8.5 2057.9 - 2.26E+06 - - - -0.5837 - 3.606 0.608 - 469.3 1 2 0 -0.001 15 0 0 0 - - - - - 8.6651 0.9999 221125_WJC_METTL3_EV_vs_WT_F10.09636.09636.3 0.000118 Nov-76 K.TQKPPQKPAPAVVSVTPAVK.D "sp|Q96CB8|INT12_HUMAN,tr|A0A087WXN4|A0A087WXN4_HUMAN" 2 2042.1888 2.65 141908 9636 3 2042.18819 681.7369 Integrator complex subunit 12 OS=Homo sapiens OX=9606 GN=INTS12 PE=1 SV=1 10.3 2058 - 222454 - - - -0.3041 - 1.891 0.488 - 105.7 1 2 0 -0.0006 20 0 0 0 3.63E+06 1.37E+06 - - - 5.5262 0.9976 221125_WJC_METTL3_EV_vs_WT_F10.09657.09657.4 0.083 16/72 R.DRRPVHLDQAAFR.T sp|Q9H0D6|XRN2_HUMAN 1 1579.8332 0.96 141919 9657 4 1579.830373 395.9656 5'-3' exoribonuclease 2 OS=Homo sapiens OX=9606 GN=XRN2 PE=1 SV=1 9.52 2060.7 - 1.44E+06 - - - -1.7622 - 2.582 0.321 - 314.2 1 2 1 -0.0028 13 0 0 0 4.09E+07 4.28E+07 - - - 2.3709 0.9423 221125_WJC_METTL3_EV_vs_WT_F10.09658.09658.2 0.0802 16-Aug V.AETAQTIK[136.11]K[136.11].S sp|Q96A49|SYAP1_HUMAN 1 1004.5837 1.4 141920 9658 2 1004.583153 503.2991 Synapse-associated protein 1 OS=Homo sapiens OX=9606 GN=SYAP1 PE=1 SV=1 8.64 2060.8 - 1.23E+06 - - - -0.5545 - 1.758 0.232 - 250.3 1 1 0 -0.0006 9 0 0 0 4.60E+07 3.28E+07 - - - 2.3866 0.92 221125_WJC_METTL3_EV_vs_WT_F10.09662.09662.2 7.92E-06 20-Nov L.GTWDNK[136.11]GPVAK[136.11].A sp|Q9Y5A9|YTHD2_HUMAN 1 1187.627 1.35 141922 9662 2 1187.628221 594.8208 YTH domain-containing family protein 2 OS=Homo sapiens OX=9606 GN=YTHDF2 PE=1 SV=2 8.59 2061.4 - 313234 - - - 1.0517 - 2.313 0.545 - 356 1 1 1 0.0013 11 0 0 0 9.38E+06 6.93E+06 - - - 5.3344 0.8681 221125_WJC_METTL3_EV_vs_WT_F10.09664.09664.2 0.00239 14-Jun A.ETAQTIKK.S sp|Q96A49|SYAP1_HUMAN 1 917.5182 1.29 141924 9664 2 917.516531 459.7664 Synapse-associated protein 1 OS=Homo sapiens OX=9606 GN=SYAP1 PE=1 SV=1 8.69 2061.6 - 509800 - - - -1.8147 - 1.408 0.278 - 124.4 1 1 0 -0.0017 8 0 0 0 1.56E+07 1.20E+07 - - - 2.1258 0.9999 221125_WJC_METTL3_EV_vs_WT_F10.09673.09673.3 3.15E-08 Nov-72 K.VSESEGKLEGQATAVTPNK.N sp|Q9BXB4|OSB11_HUMAN 1 1943.98 0.53 141929 9673 3 1943.976348 649.0006 Oxysterol-binding protein-related protein 11 OS=Homo sapiens OX=9606 GN=OSBPL11 PE=1 SV=2 4.79 2062.8 - 134212 - - - -1.8786 - 2.473 0.584 - 87.7 1 2 1 -0.0037 19 0 0 0 4.13E+06 7.78E+06 - - - 7.2745 0.9313 221125_WJC_METTL3_EV_vs_WT_F10.09674.09674.3 1.76E-07 13/60 Y.R[166.11]DPEEIEK[136.11]EEQAAAEK[136.11].A "sp|P08865|RSSA_HUMAN,tr|C9J9K3|C9J9K3_HUMAN,tr|A0A0C4DG17|A0A0C4DG17_HUMAN" 3 1896.9275 0.66 141930 9674 3 1896.919151 633.3165 40S ribosomal protein SA OS=Homo sapiens OX=9606 GN=RPSA PE=1 SV=4 4.31 2062.9 - 494368 - - - -4.4124 - 2.841 0.57 - 130.8 1 1 1 -0.0084 16 0 0 0 7.97E+06 1.22E+07 - - - 7.5718 0.978 221125_WJC_METTL3_EV_vs_WT_F10.09680.09680.3 1.62E-05 Dec-84 F.ASSLVSGLNSSASEPAK[136.11]EPAK[136.11]K[136.11].S "sp|Q86U44|MTA70_HUMAN,tr|F5H6D8|F5H6D8_HUMAN,tr|H0YFV6|H0YFV6_HUMAN,tr|B4DTN4|B4DTN4_HUMAN" 4 2181.1703 0.001 141933 9680 3 2181.167838 728.0641 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 8.54 2063.8 - 308803 - - - -1.1411 - 2.334 0.494 - 123.1 1 1 1 -0.0025 22 0 0 0 0.00E+00 1.09E+07 - - - 6.0564 0.8203 221125_WJC_METTL3_EV_vs_WT_F10.09683.09683.3 1.55 Jun-32 K.NIHLNLDRR.T "sp|Q9Y5S9|RBM8A_HUMAN,tr|A0A0J9YW13|A0A0J9YW13_HUMAN" 2 1149.6367 1.99 141934 9683 3 1149.634527 384.2195 RNA-binding protein 8A OS=Homo sapiens OX=9606 GN=RBM8A PE=1 SV=1 9.61 2064.2 - 216217 - - - -1.8806 - 0.97 0.171 - 56 1 2 0 -0.0022 9 0 0 0 4.30E+06 2.16E+06 - - - 0.3541 1 221125_WJC_METTL3_EV_vs_WT_F10.09685.09685.4 2.64E-05 18/108 R.YGDGGSTFQSTTGHC[160.03]VHMR.G "sp|P31943|HNRH1_HUMAN,tr|H0YBD7|H0YBD7_HUMAN,tr|H0YB39|H0YB39_HUMAN,tr|H0YBG7|H0YBG7_HUMAN,tr|E9PCY7|E9PCY7_HUMAN,tr|D6RIT2|D6RIT2_HUMAN,tr|G8JLB6|G8JLB6_HUMAN" 7 2096.8793 1.04 141935 9685 4 2096.88321 525.2271 Heterogeneous nuclear ribonucleoprotein H OS=Homo sapiens OX=9606 GN=HNRNPH1 PE=1 SV=4 6.91 2064.4 - 1.39E+06 - - - 1.8852 - 3.68 0.625 - 351.7 1 2 0 0.004 19 0 0 0 3.49E+08 3.35E+08 - - - 5.1057 0.9667 221125_WJC_METTL3_EV_vs_WT_F10.09686.09686.3 0.0415 Jul-84 R.AAGTDSFNGHPPQGC[160.03]ASTPVAR[166.11].E "sp|Q9NVU0|RPC5_HUMAN,tr|A0A0C4DH01|A0A0C4DH01_HUMAN" 2 2207.0053 2 141936 9686 3 2207.01024 736.6757 DNA-directed RNA polymerase III subunit RPC5 OS=Homo sapiens OX=9606 GN=POLR3E PE=1 SV=1 6.78 2064.5 - 261102 - - - 2.2229 - 1.369 0.204 - 26.1 1 2 0 0.0049 22 0 0 0 2.35E+07 1.18E+07 - - - 1.5577 0.995 221125_WJC_METTL3_EV_vs_WT_F10.09694.09694.4 0.098 Nov-78 K.RQLDTETNLHLNTK.E sp|P12270|TPR_HUMAN 1 1681.8747 2.78 141942 9694 4 1681.875762 421.476 Nucleoprotein TPR OS=Homo sapiens OX=9606 GN=TPR PE=1 SV=3 6.75 2065.6 - 231287 - - - 0.6035 - 1.938 0.224 - 108.6 1 2 0 0.001 14 0 0 0 3.67E+06 1.32E+06 - - - 1.4162 1 221125_WJC_METTL3_EV_vs_WT_F10.09699.09699.3 1.32E-13 24/88 R.TGGPAYGPSSDVSTASETESEKR.E sp|P51116|FXR2_HUMAN 1 2312.0404 1.77 141945 9699 3 2312.037525 771.6874 Fragile X mental retardation syndrome-related protein 2 OS=Homo sapiens OX=9606 GN=FXR2 PE=1 SV=2 4.41 2066.3 - 508903 - - - -1.2556 - 4.838 0.722 - 617 1 2 0 -0.0029 23 0 0 0 2.82E+07 1.59E+07 - - - 10.2872 1 221125_WJC_METTL3_EV_vs_WT_F10.09701.09701.3 7.28E-08 18/52 K.RQLDTETNLHLNTK.E sp|P12270|TPR_HUMAN 1 1681.8747 7.64 141947 9701 3 1681.873932 561.6322 Nucleoprotein TPR OS=Homo sapiens OX=9606 GN=TPR PE=1 SV=3 6.75 2066.5 - 590007 - - - -0.4846 - 3.046 0.554 - 325 1 2 0 -0.0008 14 0 0 0 8.54E+06 1.12E+06 - - - 7.6764 1 221125_WJC_METTL3_EV_vs_WT_F10.09702.09702.3 1.85E-05 21/116 R.GGGGPGGGGPGGGSAGGPSQPPGGGGPGIR.K "sp|Q92945|FUBP2_HUMAN,tr|M0R0C6|M0R0C6_HUMAN,tr|A0A087WTP3|A0A087WTP3_HUMAN" 3 2269.0584 1.45 141948 9702 3 2269.057561 757.3601 Far upstream element-binding protein 2 OS=Homo sapiens OX=9606 GN=KHSRP PE=1 SV=4 9.75 2066.7 - 456512 - - - -0.3777 - 3.156 0.552 - 193.7 1 2 0 -0.0009 30 0 0 0 1.04E+08 7.19E+07 - - - 7.3382 1 221125_WJC_METTL3_EV_vs_WT_F10.09703.09703.3 7.96E-10 21/88 R.TGGPAYGPSSDVSTASETESEK[136.11]R[166.11].E sp|P51116|FXR2_HUMAN 1 2330.0629 1.77 141949 9703 3 2330.057874 777.6949 Fragile X mental retardation syndrome-related protein 2 OS=Homo sapiens OX=9606 GN=FXR2 PE=1 SV=2 4.41 2066.8 - 445393 - - - -2.1562 - 4.305 0.679 - 553 1 2 0 -0.005 23 0 0 0 2.82E+07 1.59E+07 - - - 9.5333 1 221125_WJC_METTL3_EV_vs_WT_F10.09709.09709.3 3.63E-07 25/116 R.GGGGPGGGGPGGGSAGGPSQPPGGGGPGIR[166.11].K "sp|Q92945|FUBP2_HUMAN,tr|M0R0C6|M0R0C6_HUMAN,tr|A0A087WTP3|A0A087WTP3_HUMAN" 3 2279.0667 1.45 141953 9709 3 2279.066463 760.6962 Far upstream element-binding protein 2 OS=Homo sapiens OX=9606 GN=KHSRP PE=1 SV=4 9.75 2067.6 - 505211 - - - -0.0987 - 3.01 0.554 - 302.1 1 2 0 -0.0002 30 0 0 0 1.04E+08 7.19E+07 - - - 7.2517 0.8756 221125_WJC_METTL3_EV_vs_WT_F10.09714.09714.4 0.0184 Nov-90 K.SKDEVAQPLNLSAKPK.T "sp|P35711|SOX5_HUMAN,tr|F5H0I3|F5H0I3_HUMAN,tr|I3L0A5|I3L0A5_HUMAN" 3 1723.9468 3.81 141958 9714 4 1723.94666 431.994 Transcription factor SOX-5 OS=Homo sapiens OX=9606 GN=SOX5 PE=1 SV=3 8.22 2068.2 - 317777 - - - -0.1096 - 2.018 0.146 - 69.4 1 2 1 -0.0002 16 0 0 0 4.31E+06 1.13E+06 - - - 0.7441 1 221125_WJC_METTL3_EV_vs_WT_F10.09719.09719.3 8.11E-18 24/72 R.YGDGGSTFQSTTGHC[160.03]VHMR[166.11].G "sp|P31943|HNRH1_HUMAN,tr|H0YBD7|H0YBD7_HUMAN,tr|H0YB39|H0YB39_HUMAN,tr|H0YBG7|H0YBG7_HUMAN,tr|E9PCY7|E9PCY7_HUMAN,tr|D6RIT2|D6RIT2_HUMAN,tr|G8JLB6|G8JLB6_HUMAN" 7 2106.8875 1.17 141961 9719 3 2106.883225 703.3031 Heterogeneous nuclear ribonucleoprotein H OS=Homo sapiens OX=9606 GN=HNRNPH1 PE=1 SV=4 6.91 2068.9 - 5.80E+06 - - - -2.0419 - 4.875 0.754 - 1185.4 1 2 0 -0.0043 19 0 0 0 1.13E+08 9.70E+07 - - - 10.837 1 221125_WJC_METTL3_EV_vs_WT_F10.09720.09720.3 1.54E-16 29/72 R.YGDGGSTFQSTTGHC[160.03]VHMR.G "sp|P31943|HNRH1_HUMAN,tr|H0YBD7|H0YBD7_HUMAN,tr|H0YB39|H0YB39_HUMAN,tr|H0YBG7|H0YBG7_HUMAN,tr|E9PCY7|E9PCY7_HUMAN,tr|D6RIT2|D6RIT2_HUMAN,tr|G8JLB6|G8JLB6_HUMAN" 7 2096.8793 1.17 141962 9720 3 2096.878785 699.967 Heterogeneous nuclear ribonucleoprotein H OS=Homo sapiens OX=9606 GN=HNRNPH1 PE=1 SV=4 6.91 2068.9 - 4.80E+06 - - - -0.2251 - 5.364 0.708 - 1915.1 1 2 0 -0.0005 19 0 0 0 1.14E+08 9.70E+07 - - - 10.5601 0.9996 221125_WJC_METTL3_EV_vs_WT_F10.09721.09721.4 8.71E-05 14/84 R.FDDTNPEK[136.11]EK[136.11]EDFEK[136.11].V "sp|P07814|SYEP_HUMAN,tr|V9GYZ6|V9GYZ6_HUMAN" 2 1893.8695 1.01 141963 9721 4 1893.87056 474.4746 Bifunctional glutamate\proline--tRNA ligase OS=Homo sapiens OX=9606 GN=EPRS1 PE=1 SV=5 4.2 2069 - 419706 - - - 0.5845 - 2.167 0.417 - 166.5 1 2 2 0.0011 15 0 0 0 3.27E+07 3.22E+07 - - - 3.132 1 221125_WJC_METTL3_EV_vs_WT_F10.09722.09722.3 8.80E-08 17/96 K.AAPEEPQQR[166.11]PPEAVAAAPAGTTSSR[166.11].V "sp|Q96JP5|ZFP91_HUMAN,tr|A0A0A6YYC7|A0A0A6YYC7_HUMAN" 2 2508.2472 0.98 141964 9722 3 2508.246133 837.0897 E3 ubiquitin-protein ligase ZFP91 OS=Homo sapiens OX=9606 GN=ZFP91 PE=1 SV=1 4.79 2069.2 - 243105 - - - -0.413 - 2.374 0.592 - 174.4 1 2 0 -0.001 25 0 0 0 5.59E+06 5.70E+06 - - - 7.129 0.9995 221125_WJC_METTL3_EV_vs_WT_F10.09723.09723.4 0.00108 10/102 R.ITHQIVDRPGQQTSVIGR.C "sp|O00541|PESC_HUMAN,tr|B3KXD6|B3KXD6_HUMAN,tr|B5MCF9|B5MCF9_HUMAN" 3 2004.0865 0.07 141965 9723 4 2004.089437 502.0289 Pescadillo homolog OS=Homo sapiens OX=9606 GN=PES1 PE=1 SV=1 9.61 2069.3 - 234081 - - - 1.48 - 2.195 0.337 - 96.5 1 2 0 0.003 18 0 0 0 3.15E+06 4.46E+07 - - - 2.4277 1 221125_WJC_METTL3_EV_vs_WT_F10.09724.09724.3 2.40E-07 13/48 K.KDEVC[160.03]VNPYHYQR.V "sp|Q15796|SMAD2_HUMAN,sp|P84022|SMAD3_HUMAN,tr|H3BVD1|H3BVD1_HUMAN,tr|H0YMP2|H0YMP2_HUMAN,tr|K7EJX0|K7EJX0_HUMAN,tr|H3BP09|H3BP09_HUMAN,tr|B7Z5N5|B7Z5N5_HUMAN,tr|H0YL71|H0YL71_HUMAN" 8 1706.7835 1.32 141966 9724 3 1706.785661 569.9351 Mothers against decapentaplegic homolog 2 OS=Homo sapiens OX=9606 GN=SMAD2 PE=1 SV=1 6.74 2069.4 - 169224 - - - 1.2726 - 2.948 0.539 - 297.1 1 2 0 0.0022 13 0 0 0 9.17E+06 6.93E+06 - - - 7.48 0.9999 221125_WJC_METTL3_EV_vs_WT_F10.09731.09731.3 6.45E-06 17/56 R.FDDTNPEK[136.11]EK[136.11]EDFEK[136.11].V "sp|P07814|SYEP_HUMAN,tr|V9GYZ6|V9GYZ6_HUMAN" 2 1893.8695 1.02 141971 9731 3 1893.867148 632.2971 Bifunctional glutamate\proline--tRNA ligase OS=Homo sapiens OX=9606 GN=EPRS1 PE=1 SV=5 4.2 2070.3 - 496821 - - - -1.2171 - 2.897 0.579 - 497.4 1 2 2 -0.0023 15 0 0 0 2.64E+07 2.58E+07 - - - 7.7702 1 221125_WJC_METTL3_EV_vs_WT_F10.09733.09733.3 4.69E-06 16/48 K.K[136.11]DEVC[160.03]VNPYHYQR[166.11].V "sp|Q15796|SMAD2_HUMAN,sp|P84022|SMAD3_HUMAN,tr|H3BVD1|H3BVD1_HUMAN,tr|H0YMP2|H0YMP2_HUMAN,tr|K7EJX0|K7EJX0_HUMAN,tr|H3BP09|H3BP09_HUMAN,tr|B7Z5N5|B7Z5N5_HUMAN,tr|H0YL71|H0YL71_HUMAN" 8 1724.806 1.31 141973 9733 3 1724.80671 575.9426 Mothers against decapentaplegic homolog 2 OS=Homo sapiens OX=9606 GN=SMAD2 PE=1 SV=1 6.74 2070.6 - 328893 - - - 0.4354 - 3.161 0.582 - 482.7 1 2 0 0.0008 13 0 0 0 9.21E+06 7.05E+06 - - - 8.1489 1 221125_WJC_METTL3_EV_vs_WT_F10.09735.09735.3 2.06E-09 19/56 R.FDDTNPEKEKEDFEK.V "sp|P07814|SYEP_HUMAN,tr|V9GYZ6|V9GYZ6_HUMAN" 2 1869.8269 1.01 141975 9735 3 1869.82663 624.2829 Bifunctional glutamate\proline--tRNA ligase OS=Homo sapiens OX=9606 GN=EPRS1 PE=1 SV=5 4.2 2070.8 - 301581 - - - -0.1193 - 3.4 0.632 - 621.2 1 2 2 -0.0002 15 0 0 0 2.65E+07 2.61E+07 - - - 8.7794 0.9999 221125_WJC_METTL3_EV_vs_WT_F10.09736.09736.2 0.000234 20-Nov R.VEIIANDQGNR[166.11].L "sp|P11021|BIP_HUMAN,sp|P48741|HSP77_HUMAN,sp|P54652|HSP72_HUMAN,sp|P0DMV8|HS71A_HUMAN,sp|P34931|HS71L_HUMAN,sp|P11142|HSP7C_HUMAN,sp|P0DMV9|HS71B_HUMAN,sp|P17066|HSP76_HUMAN,tr|E9PQQ4|E9PQQ4_HUMAN,tr|E9PNE6|E9PNE6_HUMAN,tr|E9PKE3|E9PKE3_HUMAN,tr|A0A7P0TB36|A0A7P0TB36_HUMAN,tr|E9PLF4|E9PLF4_HUMAN,tr|A0A7P0TAI0|A0A7P0TAI0_HUMAN,tr|Q53FA3|Q53FA3_HUMAN,tr|E9PI65|E9PI65_HUMAN,tr|E9PK54|E9PK54_HUMAN,tr|E9PN25|E9PN25_HUMAN,tr|E9PPY6|E9PPY6_HUMAN,tr|E9PQK7|E9PQK7_HUMAN,tr|A0A0G2JIW1|A0A0G2JIW1_HUMAN" 21 1237.629 0.16 141976 9736 2 1237.628673 619.8218 Endoplasmic reticulum chaperone BiP OS=Homo sapiens OX=9606 GN=HSPA5 PE=1 SV=2 4.37 2071 - 283534 - - - -0.2917 - 2.184 0.483 - 484.2 1 2 0 -0.0004 11 0 0 0 1.47E+06 9.00E+06 - - - 4.7215 1 221125_WJC_METTL3_EV_vs_WT_F10.09737.09737.3 6.44E-07 14/96 K.AAPEEPQQRPPEAVAAAPAGTTSSR.V "sp|Q96JP5|ZFP91_HUMAN,tr|A0A0A6YYC7|A0A0A6YYC7_HUMAN" 2 2488.2306 0.96 141977 9737 3 2488.228232 830.4175 E3 ubiquitin-protein ligase ZFP91 OS=Homo sapiens OX=9606 GN=ZFP91 PE=1 SV=1 4.79 2071.1 - 283182 - - - -0.9633 - 2.425 0.582 - 138.9 1 2 0 -0.0024 25 0 0 0 5.49E+06 5.70E+06 - - - 7.066 1 221125_WJC_METTL3_EV_vs_WT_F10.09741.09741.4 5.76E-07 15/72 K.KDEVC[160.03]VNPYHYQR.V "sp|Q15796|SMAD2_HUMAN,sp|P84022|SMAD3_HUMAN,tr|H3BVD1|H3BVD1_HUMAN,tr|H0YMP2|H0YMP2_HUMAN,tr|K7EJX0|K7EJX0_HUMAN,tr|H3BP09|H3BP09_HUMAN,tr|B7Z5N5|B7Z5N5_HUMAN,tr|H0YL71|H0YL71_HUMAN" 8 1706.7835 0.6 141979 9741 4 1706.784811 427.7031 Mothers against decapentaplegic homolog 2 OS=Homo sapiens OX=9606 GN=SMAD2 PE=1 SV=1 6.74 2071.7 - 715272 - - - 0.7746 - 2.985 0.516 - 351.8 1 2 0 0.0013 13 0 0 0 7.62E+06 1.27E+07 - - - 4.1224 0.9989 221125_WJC_METTL3_EV_vs_WT_F10.09742.09742.3 2.87E-06 13/76 K.VPSPPDEHQEAENAVSSGNR.D sp|Q9BXS6|NUSAP_HUMAN 1 2118.9566 1.34 141980 9742 3 2118.966702 707.3262 Nucleolar and spindle-associated protein 1 OS=Homo sapiens OX=9606 GN=NUSAP1 PE=1 SV=1 4.4 2071.8 - 308678 - - - 4.749 - 2.872 0.388 - 224.7 1 2 0 0.0101 20 0 0 0 1.49E+07 1.11E+07 - - - 5.4225 1 221125_WJC_METTL3_EV_vs_WT_F10.09744.09744.3 6.33E-09 18/64 K.TK[136.11]ENVNATENC[160.03]ISAVGK[136.11].L "sp|O00410|IPO5_HUMAN,tr|H0Y8C6|H0Y8C6_HUMAN" 2 1849.9175 0.98 141982 9744 3 1849.916417 617.6464 Importin-5 OS=Homo sapiens OX=9606 GN=IPO5 PE=1 SV=4 5.81 2072 - 536163 - - - -0.573 - 3.177 0.618 - 445 1 2 1 -0.0011 17 0 0 0 2.74E+07 2.80E+07 - - - 8.35 0.9876 221125_WJC_METTL3_EV_vs_WT_F10.09747.09747.2 8.57E-05 20-Oct F.QSTTGHC[160.03]VHMR.G "sp|P55795|HNRH2_HUMAN,sp|P52597|HNRPF_HUMAN,sp|P31943|HNRH1_HUMAN,tr|H0YBD7|H0YBD7_HUMAN,tr|H0YB39|H0YB39_HUMAN,tr|H0YBG7|H0YBG7_HUMAN,tr|E9PCY7|E9PCY7_HUMAN,tr|D6RIT2|D6RIT2_HUMAN,tr|G8JLB6|G8JLB6_HUMAN" 9 1312.5765 1.1 141985 9747 2 1312.579003 657.2955 Heterogeneous nuclear ribonucleoprotein H2 OS=Homo sapiens OX=9606 GN=HNRNPH2 PE=1 SV=1 8.27 2072.4 - 222995 - - - 1.9275 - 2.182 0.57 - 516 1 1 0 0.0025 11 0 0 0 2.12E+06 1.93E+06 - - - 5.361 1 221125_WJC_METTL3_EV_vs_WT_F10.09749.09749.2 5.18E-10 21/34 K.SIHANFSSGVGTTAASSK[136.11].N "sp|Q8IWZ3|ANKH1_HUMAN,tr|A0A0A0MQZ8|A0A0A0MQZ8_HUMAN,tr|H0Y472|H0Y472_HUMAN,tr|H0Y7Y3|H0Y7Y3_HUMAN,tr|H0Y4P6|H0Y4P6_HUMAN,tr|H0Y785|H0Y785_HUMAN" 6 1728.8522 1.35 141987 9749 2 1728.858351 865.4334 Ankyrin repeat and KH domain-containing protein 1 OS=Homo sapiens OX=9606 GN=ANKHD1 PE=1 SV=1 8.49 2072.6 - 156734 - - - 3.5422 - 3.659 0.694 - 1129.6 1 2 0 0.0061 18 0 0 0 2.41E+06 1.78E+06 - - - 7.3542 1 221125_WJC_METTL3_EV_vs_WT_F10.09750.09750.2 3.56E-13 22/34 K.SIHANFSSGVGTTAASSK.N "sp|Q8IWZ3|ANKH1_HUMAN,tr|A0A0A0MQZ8|A0A0A0MQZ8_HUMAN,tr|H0Y472|H0Y472_HUMAN,tr|H0Y7Y3|H0Y7Y3_HUMAN,tr|H0Y4P6|H0Y4P6_HUMAN,tr|H0Y785|H0Y785_HUMAN" 6 1720.838 1.35 141988 9750 2 1720.838093 861.4263 Ankyrin repeat and KH domain-containing protein 1 OS=Homo sapiens OX=9606 GN=ANKHD1 PE=1 SV=1 8.49 2072.8 - 149834 - - - 0.0384 - 3.964 0.716 - 1313.5 1 2 0 0.0001 18 0 0 0 2.41E+06 1.78E+06 - - - 7.7154 1 221125_WJC_METTL3_EV_vs_WT_F10.09753.09753.3 5.58E-08 19/64 K.TKENVNATENC[160.03]ISAVGK.L "sp|O00410|IPO5_HUMAN,tr|H0Y8C6|H0Y8C6_HUMAN" 2 1833.8891 0.88 141989 9753 3 1833.88579 612.3036 Importin-5 OS=Homo sapiens OX=9606 GN=IPO5 PE=1 SV=4 5.81 2073.2 - 657416 - - - -1.7924 - 3.557 0.613 - 576.8 1 2 1 -0.0033 17 0 0 0 2.45E+07 2.78E+07 - - - 8.5791 0.9994 221125_WJC_METTL3_EV_vs_WT_F10.09754.09754.4 0.000355 15/90 K.DLVIERPRPDSRPAVK.K "sp|Q9Y520|PRC2C_HUMAN,tr|E7EPN9|E7EPN9_HUMAN" 2 1847.0377 0.94 141990 9754 4 1847.037212 462.7667 Protein PRRC2C OS=Homo sapiens OX=9606 GN=PRRC2C PE=1 SV=4 8.74 2073.3 - 380444 - - - -0.2804 - 2.422 0.316 - 165.9 1 2 0 -0.0005 16 0 0 0 5.81E+07 6.19E+07 - - - 2.2879 1 221125_WJC_METTL3_EV_vs_WT_F10.09756.09756.4 8.43E-05 Oct-90 K.GHSAAVHSFAFSNDSR.R "sp|Q9Y4P3|TBL2_HUMAN,tr|E9PF19|E9PF19_HUMAN,tr|Q96E41|Q96E41_HUMAN" 3 1688.7655 1.65 141992 9756 4 1688.765792 423.1987 Transducin beta-like protein 2 OS=Homo sapiens OX=9606 GN=TBL2 PE=1 SV=1 6.92 2073.5 - 365065 - - - 0.1546 - 2.182 0.482 - 58.2 1 2 0 0.0003 16 0 0 0 4.17E+06 2.52E+06 - - - 3.6961 0.9581 221125_WJC_METTL3_EV_vs_WT_F10.09757.09757.4 0.133 10/102 K.VKLDSPAGTALSPSGHTK.L "sp|P32322|P5CR1_HUMAN,tr|E2QRB3|E2QRB3_HUMAN" 2 1764.937 2.22 141993 9757 4 1764.93832 442.2415 "Pyrroline-5-carboxylate reductase 1, mitochondrial OS=Homo sapiens OX=9606 GN=PYCR1 PE=1 SV=2" 8.57 2073.7 - 281434 - - - 0.7405 - 1.534 0.203 - 48.8 1 2 1 0.0013 18 0 0 0 1.52E+07 6.85E+06 - - - 1.1391 1 221125_WJC_METTL3_EV_vs_WT_F10.09758.09758.3 1.49E-06 13/68 K.KTFDEC[160.03]VAEGGSDC[160.03]APEK.L sp|Q7LGA3|HS2ST_HUMAN 1 1998.8299 2.35 141994 9758 3 1998.825157 667.2839 Heparan sulfate 2-O-sulfotransferase 1 OS=Homo sapiens OX=9606 GN=HS2ST1 PE=1 SV=1 4.18 2073.8 - 209181 - - - -2.3764 - 2.847 0.676 - 237 1 2 0 -0.0047 18 0 0 0 1.75E+06 7.43E+05 - - - 8.6807 0.9999 221125_WJC_METTL3_EV_vs_WT_F10.09773.09773.4 4.38E-06 16/84 R.FDDTNPEKEKEDFEK.V "sp|P07814|SYEP_HUMAN,tr|V9GYZ6|V9GYZ6_HUMAN" 2 1869.8269 1.02 142005 9773 4 1869.829386 468.464 Bifunctional glutamate\proline--tRNA ligase OS=Homo sapiens OX=9606 GN=EPRS1 PE=1 SV=5 4.2 2075.8 - 2.22E+06 - - - 1.3547 - 2.538 0.571 - 172.4 1 2 2 0.0025 15 0 0 0 3.27E+07 3.21E+07 - - - 4.5285 1 221125_WJC_METTL3_EV_vs_WT_F10.09775.09775.3 4.65E-08 27/84 R.GHGRPAAAVAQPLEPGPGPPER.A sp|Q14681|KCTD2_HUMAN 1 2160.1188 6.17 142007 9775 3 2160.121288 721.0469 BTB\POZ domain-containing protein KCTD2 OS=Homo sapiens OX=9606 GN=KCTD2 PE=1 SV=3 6.76 2076.1 - 710359 - - - 1.136 - 4.675 0.634 - 678.9 1 2 0 0.0025 22 0 0 0 1.30E+08 2.10E+07 - - - 9.2642 0.9808 221125_WJC_METTL3_EV_vs_WT_F10.09777.09777.2 0.00725 Jun-32 K.TK[136.11]ENVNATENC[160.03]ISAVGK[136.11].L "sp|O00410|IPO5_HUMAN,tr|H0Y8C6|H0Y8C6_HUMAN" 2 1849.9175 0.35 142009 9777 2 1849.916985 925.966 Importin-5 OS=Homo sapiens OX=9606 GN=IPO5 PE=1 SV=4 5.81 2076.3 - 104856 - - - -0.266 - 1.246 0.314 - 92.4 1 2 1 -0.0005 17 0 0 0 4.93E+05 1.41E+06 - - - 1.9008 0.9924 221125_WJC_METTL3_EV_vs_WT_F10.09781.09781.3 0.0296 Oct-56 K.LITQTFSHHNQLAQK.T "sp|Q9Y266|NUDC_HUMAN,tr|A0A0A0MSS4|A0A0A0MSS4_HUMAN,tr|A0A0A0MSU9|A0A0A0MSU9_HUMAN" 3 1764.9271 1.53 142011 9781 3 1764.930775 589.3163 Nuclear migration protein nudC OS=Homo sapiens OX=9606 GN=NUDC PE=1 SV=1 8.76 2076.9 - 401201 - - - 2.0726 - 1.871 0.201 - 73 1 2 0 0.0037 15 0 0 0 1.39E+07 9.11E+06 - - - 2.4146 1 221125_WJC_METTL3_EV_vs_WT_F10.09783.09783.4 4.49E-08 25/126 R.GHGRPAAAVAQPLEPGPGPPER.A sp|Q14681|KCTD2_HUMAN 1 2160.1188 5.79 142013 9783 4 2160.122828 541.037 BTB\POZ domain-containing protein KCTD2 OS=Homo sapiens OX=9606 GN=KCTD2 PE=1 SV=3 6.76 2077.1 - 3.36E+06 - - - 1.849 - 4.141 0.611 - 448 1 2 0 0.004 22 0 0 0 3.42E+08 5.91E+07 - - - 5.008 1 221125_WJC_METTL3_EV_vs_WT_F10.09785.09785.3 9.31E-07 Dec-60 K.GHSAAVHSFAFSNDSR.R "sp|Q9Y4P3|TBL2_HUMAN,tr|E9PF19|E9PF19_HUMAN,tr|Q96E41|Q96E41_HUMAN" 3 1688.7655 1.17 142015 9785 3 1688.765472 563.9291 Transducin beta-like protein 2 OS=Homo sapiens OX=9606 GN=TBL2 PE=1 SV=1 6.92 2077.3 - 253882 - - - -0.0349 - 2.742 0.575 - 174 1 2 0 -0.0001 16 0 0 0 5.80E+06 4.95E+06 - - - 7.5388 0.9999 221125_WJC_METTL3_EV_vs_WT_F10.09789.09789.3 0.00017 15/48 R.HR[166.11]LDLGEDYPSGK[136.11].K sp|O43143|DHX15_HUMAN 1 1503.7437 1.21 142017 9789 3 1503.742804 502.2552 Pre-mRNA-splicing factor ATP-dependent RNA helicase DHX15 OS=Homo sapiens OX=9606 GN=DHX15 PE=1 SV=2 5.38 2077.9 - 230419 - - - -0.5799 - 2.515 0.494 - 343.2 1 2 1 -0.0009 13 0 0 0 1.89E+07 1.56E+07 - - - 6.5479 0.9902 221125_WJC_METTL3_EV_vs_WT_F10.09790.09790.4 0.281 14/102 K.VK[136.11]LDSPAGTALSPSGHTK[136.11].L "sp|P32322|P5CR1_HUMAN,tr|E2QRB3|E2QRB3_HUMAN" 2 1780.9654 2.23 142018 9790 4 1780.965107 446.2486 "Pyrroline-5-carboxylate reductase 1, mitochondrial OS=Homo sapiens OX=9606 GN=PYCR1 PE=1 SV=2" 8.57 2078 - 241997 - - - -0.1718 - 2.154 0.252 - 84.5 1 2 1 -0.0003 18 0 0 0 1.53E+07 6.85E+06 - - - 1.6822 0.9979 221125_WJC_METTL3_EV_vs_WT_F10.09792.09792.3 0.00159 13/60 K.DLVIER[166.11]PR[166.11]PDSR[166.11]PAVK[136.11].K "sp|Q9Y520|PRC2C_HUMAN,tr|E7EPN9|E7EPN9_HUMAN" 2 1885.0767 0.97 142020 9792 3 1885.081466 629.3662 Protein PRRC2C OS=Homo sapiens OX=9606 GN=PRRC2C PE=1 SV=4 8.74 2078.2 - 339846 - - - 2.5071 - 1.643 0.329 - 69.4 1 2 0 0.0047 16 0 0 0 1.16E+07 1.20E+07 - - - 3.4807 0.9962 221125_WJC_METTL3_EV_vs_WT_F10.09797.09797.3 3.06E-07 Oct-52 D.DAHPTLVTYADHSK[136.11].L "sp|Q86U44|MTA70_HUMAN,tr|F5H6D8|F5H6D8_HUMAN,tr|H0YFV6|H0YFV6_HUMAN,tr|B4DTN4|B4DTN4_HUMAN" 4 1561.7616 0.02 142023 9797 3 1561.762803 521.5945 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 5.98 2078.9 - 266760 - - - 0.7568 - 2.096 0.517 - 115.6 1 1 0 0.0012 14 0 0 0 1.09E+05 5.74E+06 - - - 6.2704 0.9999 221125_WJC_METTL3_EV_vs_WT_F10.09799.09799.4 4.83E-06 15/90 K.DLVIER[166.11]PR[166.11]PDSR[166.11]PAVK[136.11].K "sp|Q9Y520|PRC2C_HUMAN,tr|E7EPN9|E7EPN9_HUMAN" 2 1885.0767 0.98 142025 9799 4 1885.080146 472.2765 Protein PRRC2C OS=Homo sapiens OX=9606 GN=PRRC2C PE=1 SV=4 8.74 2079.1 - 2.29E+06 - - - 1.8068 - 2.673 0.434 - 144.6 1 2 0 0.0034 16 0 0 0 5.81E+07 5.90E+07 - - - 3.3489 0.9799 221125_WJC_METTL3_EV_vs_WT_F10.09801.09801.2 0.0122 14-Sep E.PGPGPPER.A sp|Q14681|KCTD2_HUMAN 1 805.4083 4.29 142027 9801 2 805.408407 403.7114 BTB\POZ domain-containing protein KCTD2 OS=Homo sapiens OX=9606 GN=KCTD2 PE=1 SV=3 6.43 2079.4 - 206909 - - - 0.1924 - 1.765 0.365 - 251.9 1 1 0 0.0002 8 0 0 0 9.03E+06 2.10E+06 - - - 3.4504 0.9929 221125_WJC_METTL3_EV_vs_WT_F10.09805.09805.3 0.00386 May-88 R.ASLEEPPDGPSAGQATGPGEGR[166.11]R[166.11].S "sp|Q9BVG9|PTSS2_HUMAN,tr|E9PS47|E9PS47_HUMAN,tr|E9PLE4|E9PLE4_HUMAN" 3 2255.0681 2.14 142031 9805 3 2255.062935 752.6967 Phosphatidylserine synthase 2 OS=Homo sapiens OX=9606 GN=PTDSS2 PE=1 SV=1 4.41 2079.9 - 123048 - - - -2.309 - 1.421 0.296 - 16.6 2 2 0 -0.0052 23 0 0 0 4.46E+06 2.08E+06 - - - 2.5236 1 221125_WJC_METTL3_EV_vs_WT_F10.09810.09810.3 7.30E-12 20/76 K.EGEEPTVYSDEEEPKDESAR.K sp|O00264|PGRC1_HUMAN 1 2294.9663 4.44 142034 9810 3 2294.969446 765.996 Membrane-associated progesterone receptor component 1 OS=Homo sapiens OX=9606 GN=PGRMC1 PE=1 SV=3 3.89 2080.6 - 202645 - - - 1.3883 - 3.56 0.633 - 463.7 1 2 1 0.0032 20 0 0 0 6.04E+06 1.36E+06 - - - 8.6769 0.9851 221125_WJC_METTL3_EV_vs_WT_F10.09818.09818.3 0.0222 Dec-60 K.DLVIERPRPDSRPAVK.K "sp|Q9Y520|PRC2C_HUMAN,tr|E7EPN9|E7EPN9_HUMAN" 2 1847.0377 0.97 142040 9818 3 1847.040173 616.6865 Protein PRRC2C OS=Homo sapiens OX=9606 GN=PRRC2C PE=1 SV=4 8.74 2081.5 - 501926 - - - 1.3227 - 1.548 0.185 - 63.9 1 2 0 0.0024 16 0 0 0 1.16E+07 1.20E+07 - - - 1.7231 0.9964 221125_WJC_METTL3_EV_vs_WT_F10.09819.09819.4 1.20E-05 Nov-78 D.DAHPTLVTYADHSK[136.11].L "sp|Q86U44|MTA70_HUMAN,tr|F5H6D8|F5H6D8_HUMAN,tr|H0YFV6|H0YFV6_HUMAN,tr|B4DTN4|B4DTN4_HUMAN" 4 1561.7616 0.01 142041 9819 4 1561.763028 391.4477 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 5.98 2081.7 - 245855 - - - 0.9009 - 1.83 0.527 - 67.7 1 1 0 0.0014 14 0 0 0 3.46E+04 3.64E+06 - - - 4.0326 1 221125_WJC_METTL3_EV_vs_WT_F10.09820.09820.3 2.44E-09 30/84 R.GHGR[166.11]PAAAVAQPLEPGPGPPER[166.11].A sp|Q14681|KCTD2_HUMAN 1 2180.1354 6.17 142042 9820 3 2180.135819 727.7191 BTB\POZ domain-containing protein KCTD2 OS=Homo sapiens OX=9606 GN=KCTD2 PE=1 SV=3 6.76 2081.8 - 677422 - - - 0.2041 - 4.263 0.628 - 912.7 1 2 0 0.0004 22 0 0 0 1.30E+08 2.10E+07 - - - 8.9791 1 221125_WJC_METTL3_EV_vs_WT_F10.09827.09827.4 3.69E-10 25/126 R.GHGR[166.11]PAAAVAQPLEPGPGPPER[166.11].A sp|Q14681|KCTD2_HUMAN 1 2180.1354 5.79 142047 9827 4 2180.137212 546.0411 BTB\POZ domain-containing protein KCTD2 OS=Homo sapiens OX=9606 GN=KCTD2 PE=1 SV=3 6.76 2082.7 - 2.39E+06 - - - 0.8431 - 4.392 0.612 - 571.1 1 2 0 0.0018 22 0 0 0 3.42E+08 5.91E+07 - - - 5.0365 0.9999 221125_WJC_METTL3_EV_vs_WT_F10.09836.09836.4 0.000595 17/96 R.EENPLNHNVVDASTAHR.L "sp|Q6W2J9|BCOR_HUMAN,tr|H7BZ37|H7BZ37_HUMAN,tr|H7C2V9|H7C2V9_HUMAN,tr|A0A5F9ZGX7|A0A5F9ZGX7_HUMAN,tr|H7BYY2|H7BYY2_HUMAN,tr|H7C231|H7C231_HUMAN" 6 1901.898 2.34 142054 9836 4 1901.89869 476.4818 BCL-6 corepressor OS=Homo sapiens OX=9606 GN=BCOR PE=1 SV=1 5.28 2083.8 - 404472 - - - 0.3617 - 1.991 0.432 - 144.5 1 2 0 0.0007 17 0 0 0 2.17E+08 9.26E+07 - - - 3.225 0.9976 221125_WJC_METTL3_EV_vs_WT_F10.09839.09839.3 0.124 Oct-36 R.K[136.11]QDSGHLDLR[166.11].N "sp|Q86U44|MTA70_HUMAN,tr|B4E349|B4E349_HUMAN,tr|F5H6D8|F5H6D8_HUMAN,tr|B4DTN4|B4DTN4_HUMAN" 4 1185.6221 0.02 142057 9839 3 1185.620875 396.2146 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 6.75 2084.2 - 287604 - - - -1.0374 - 1.367 0.292 - 139.8 1 2 0 -0.0012 10 0 0 0 1.06E+05 4.92E+06 - - - 2.7082 0.9858 221125_WJC_METTL3_EV_vs_WT_F10.09843.09843.3 3.25E-05 Oct-40 H.PTLVTYADHSK[136.11].L "sp|Q86U44|MTA70_HUMAN,tr|F5H6D8|F5H6D8_HUMAN,tr|H0YFV6|H0YFV6_HUMAN,tr|B4DTN4|B4DTN4_HUMAN" 4 1238.6387 0.15 142059 9843 3 1238.641494 413.8868 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 7.16 2084.7 - 400676 - - - 2.2945 - 2.242 0.44 - 102.8 1 1 0 0.0028 11 0 0 0 8.51E+05 5.85E+06 - - - 5.7384 1 221125_WJC_METTL3_EV_vs_WT_F10.09855.09855.3 1.07E-05 23/68 R.R[166.11]C[160.03]SAGLGALAQR[166.11]PGSVSK[136.11].W "sp|Q9NXV2|KCTD5_HUMAN,tr|H3BSS5|H3BSS5_HUMAN" 2 1841.9888 4.74 142067 9855 3 1841.98783 615.0036 BTB\POZ domain-containing protein KCTD5 OS=Homo sapiens OX=9606 GN=KCTD5 PE=1 SV=1 10.86 2086.2 - 410971 - - - -0.5483 - 3.813 0.521 - 629.4 1 2 0 -0.001 18 0 0 0 4.21E+08 8.88E+07 - - - 7.6811 0.9999 221125_WJC_METTL3_EV_vs_WT_F10.09858.09858.3 0.00141 Oct-64 R.IGGGDTTEHIQTHFESK[136.11].T "sp|O14497|ARI1A_HUMAN,sp|Q8NFD5|ARI1B_HUMAN,tr|A0A3F2YNW7|A0A3F2YNW7_HUMAN,tr|A0A1B0GTJ8|A0A1B0GTJ8_HUMAN,tr|H0Y488|H0Y488_HUMAN,tr|A0A6Q8NVI4|A0A6Q8NVI4_HUMAN,tr|A0A1B0GTU5|A0A1B0GTU5_HUMAN,tr|A0A1B0GVK1|A0A1B0GVK1_HUMAN,tr|H0Y7H8|H0Y7H8_HUMAN,tr|A0A1B0GV63|A0A1B0GV63_HUMAN,tr|A0A1B0GWJ2|A0A1B0GWJ2_HUMAN" 11 1863.8843 0.89 142070 9858 3 1863.882196 622.302 AT-rich interactive domain-containing protein 1A OS=Homo sapiens OX=9606 GN=ARID1A PE=1 SV=3 5.27 2086.6 - 252218 - - - -1.1052 - 2.165 0.408 - 133.7 1 2 0 -0.0021 17 0 0 0 2.03E+07 2.29E+07 - - - 5.0396 1 221125_WJC_METTL3_EV_vs_WT_F10.09864.09864.3 0.000252 17/68 R.RC[160.03]SAGLGALAQRPGSVSK.W "sp|Q9NXV2|KCTD5_HUMAN,tr|H3BSS5|H3BSS5_HUMAN" 2 1813.9581 4.72 142074 9864 3 1813.959064 605.66 BTB\POZ domain-containing protein KCTD5 OS=Homo sapiens OX=9606 GN=KCTD5 PE=1 SV=1 10.86 2087.2 - 2.57E+06 - - - 0.5314 - 3.211 0.476 - 324.6 1 2 0 0.001 18 0 0 0 4.19E+08 8.88E+07 - - - 6.7516 1 221125_WJC_METTL3_EV_vs_WT_F10.09865.09865.3 8.80E-07 16/64 R.EENPLNHNVVDASTAHR.L "sp|Q6W2J9|BCOR_HUMAN,tr|H7BZ37|H7BZ37_HUMAN,tr|H7C2V9|H7C2V9_HUMAN,tr|A0A5F9ZGX7|A0A5F9ZGX7_HUMAN,tr|H7BYY2|H7BYY2_HUMAN,tr|H7C231|H7C231_HUMAN" 6 1901.898 3.15 142075 9865 3 1901.899687 634.9733 BCL-6 corepressor OS=Homo sapiens OX=9606 GN=BCOR PE=1 SV=1 5.28 2087.4 - 796342 - - - 0.886 - 3.239 0.591 - 242.7 1 2 0 0.0017 17 0 0 0 1.30E+08 4.14E+07 - - - 8.0977 0.999 221125_WJC_METTL3_EV_vs_WT_F10.09866.09866.4 0.00124 Oct-96 R.IGGGDTTEHIQTHFESK.T "sp|O14497|ARI1A_HUMAN,sp|Q8NFD5|ARI1B_HUMAN,tr|A0A3F2YNW7|A0A3F2YNW7_HUMAN,tr|A0A1B0GTJ8|A0A1B0GTJ8_HUMAN,tr|H0Y488|H0Y488_HUMAN,tr|A0A6Q8NVI4|A0A6Q8NVI4_HUMAN,tr|A0A1B0GTU5|A0A1B0GTU5_HUMAN,tr|A0A1B0GVK1|A0A1B0GVK1_HUMAN,tr|H0Y7H8|H0Y7H8_HUMAN,tr|A0A1B0GV63|A0A1B0GV63_HUMAN,tr|A0A1B0GWJ2|A0A1B0GWJ2_HUMAN" 11 1855.8701 1.01 142076 9866 4 1855.873926 464.9748 AT-rich interactive domain-containing protein 1A OS=Homo sapiens OX=9606 GN=ARID1A PE=1 SV=3 5.27 2087.5 - 514333 - - - 2.0853 - 1.966 0.326 - 48.4 1 2 0 0.0039 17 0 0 0 1.89E+07 1.86E+07 - - - 2.2971 1 221125_WJC_METTL3_EV_vs_WT_F10.09867.09867.3 3.70E-09 17/64 R.EENPLNHNVVDASTAHR[166.11].L "sp|Q6W2J9|BCOR_HUMAN,tr|H7BZ37|H7BZ37_HUMAN,tr|H7C2V9|H7C2V9_HUMAN,tr|A0A5F9ZGX7|A0A5F9ZGX7_HUMAN,tr|H7BYY2|H7BYY2_HUMAN,tr|H7C231|H7C231_HUMAN" 6 1911.9063 3.15 142077 9867 3 1911.905605 638.3094 BCL-6 corepressor OS=Homo sapiens OX=9606 GN=BCOR PE=1 SV=1 5.28 2087.6 - 432199 - - - -0.3489 - 2.913 0.647 - 360.5 1 2 0 -0.0007 17 0 0 0 1.30E+08 4.14E+07 - - - 8.4543 1 221125_WJC_METTL3_EV_vs_WT_F10.09873.09873.4 4.78E-06 18/102 R.RC[160.03]SAGLGALAQRPGSVSK.W "sp|Q9NXV2|KCTD5_HUMAN,tr|H3BSS5|H3BSS5_HUMAN" 2 1813.9581 4.7 142081 9873 4 1813.958839 454.4968 BTB\POZ domain-containing protein KCTD5 OS=Homo sapiens OX=9606 GN=KCTD5 PE=1 SV=1 10.86 2088.3 - 3.10E+06 - - - 0.4074 - 2.997 0.491 - 238.9 1 2 0 0.0007 18 0 0 0 2.02E+08 4.29E+07 - - - 3.8755 1 221125_WJC_METTL3_EV_vs_WT_F10.09878.09878.4 1.92E-06 15/96 R.EENPLNHNVVDASTAHR[166.11].L "sp|Q6W2J9|BCOR_HUMAN,tr|H7BZ37|H7BZ37_HUMAN,tr|H7C2V9|H7C2V9_HUMAN,tr|A0A5F9ZGX7|A0A5F9ZGX7_HUMAN,tr|H7BYY2|H7BYY2_HUMAN,tr|H7C231|H7C231_HUMAN" 6 1911.9063 2.34 142084 9878 4 1911.90706 478.9838 BCL-6 corepressor OS=Homo sapiens OX=9606 GN=BCOR PE=1 SV=1 5.28 2088.9 - 1.34E+06 - - - 0.4122 - 2.73 0.48 - 197.1 1 2 0 0.0008 17 0 0 0 2.17E+08 9.27E+07 - - - 3.7524 1 221125_WJC_METTL3_EV_vs_WT_F10.09879.09879.4 3.93E-06 19/102 R.R[166.11]C[160.03]SAGLGALAQR[166.11]PGSVSK[136.11].W "sp|Q9NXV2|KCTD5_HUMAN,tr|H3BSS5|H3BSS5_HUMAN" 2 1841.9888 4.71 142085 9879 4 1841.990269 461.5045 BTB\POZ domain-containing protein KCTD5 OS=Homo sapiens OX=9606 GN=KCTD5 PE=1 SV=1 10.86 2089 - 1.03E+06 - - - 0.7758 - 2.982 0.503 - 269.3 1 2 0 0.0014 18 0 0 0 2.02E+08 4.30E+07 - - - 3.978 0.9992 221125_WJC_METTL3_EV_vs_WT_F10.09881.09881.4 0.0138 18/102 K.QLGDSPAEDKSSFKPYSK.G sp|Q9H7S9|ZN703_HUMAN 1 1982.9585 1.58 142087 9881 4 1982.960295 496.7469 Zinc finger protein 703 OS=Homo sapiens OX=9606 GN=ZNF703 PE=1 SV=1 6.12 2089.2 - 534167 - - - 0.8871 - 2.772 0.369 - 221.7 1 2 1 0.0018 18 0 0 0 2.50E+07 1.58E+07 - - - 2.7865 0.9998 221125_WJC_METTL3_EV_vs_WT_F10.09889.09889.4 2.06E-05 16/102 K.QLGDSPAEDK[136.11]SSFK[136.11]PYSK[136.11].G sp|Q9H7S9|ZN703_HUMAN 1 2007.0011 1.58 142093 9889 4 2006.998935 502.7576 Zinc finger protein 703 OS=Homo sapiens OX=9606 GN=ZNF703 PE=1 SV=1 6.12 2090 - 450911 - - - -1.0967 - 3.143 0.451 - 213.7 1 2 1 -0.0022 18 0 0 0 2.50E+07 1.58E+07 - - - 3.5432 0.9904 221125_WJC_METTL3_EV_vs_WT_F10.09891.09891.3 0.0307 Jul-68 K.EGHPVTSEPSRPEPAVFK.A sp|Q16762|THTR_HUMAN 1 1962.9799 7.36 142095 9891 3 1962.984647 655.3339 Thiosulfate sulfurtransferase OS=Homo sapiens OX=9606 GN=TST PE=1 SV=4 5.5 2090.3 - 151914 - - - 2.3979 - 1.589 0.243 - 42.6 1 2 0 0.0047 18 0 0 0 1.01E+07 1.38E+06 - - - 2.4011 0.9998 221125_WJC_METTL3_EV_vs_WT_F10.09896.09896.3 1.05E-05 13/68 K.QLGDSPAEDKSSFKPYSK.G sp|Q9H7S9|ZN703_HUMAN 1 1982.9585 1.49 142098 9896 3 1982.959215 661.9935 Zinc finger protein 703 OS=Homo sapiens OX=9606 GN=ZNF703 PE=1 SV=1 6.12 2091 - 269940 - - - 0.3424 - 2.3 0.517 - 141.1 1 2 1 0.0007 18 0 0 0 8.21E+06 5.52E+06 - - - 6.3779 1 221125_WJC_METTL3_EV_vs_WT_F10.09900.09900.3 0.0018 Oct-60 R.DGQVINETSQHHDDLE.- sp|P08670|VIME_HUMAN 1 1835.7922 - 142100 9900 3 1835.788734 612.938 Vimentin OS=Homo sapiens OX=9606 GN=VIM PE=1 SV=4 4.28 2091.5 - 3.55E+06 - - - -1.8875 - 2.372 0.529 - 122.7 1 2 0 -0.0035 16 0 0 0 - - - - - 6.6531 0.9727 221125_WJC_METTL3_EV_vs_WT_F10.09901.09901.2 0.00167 22-Nov L.GALAQRPGSVSK.W "sp|Q9NXV2|KCTD5_HUMAN,tr|H3BSS5|H3BSS5_HUMAN" 2 1169.6517 6.38 142101 9901 2 1169.654162 585.8331 BTB\POZ domain-containing protein KCTD5 OS=Homo sapiens OX=9606 GN=KCTD5 PE=1 SV=1 11 2091.6 - 571735 - - - 2.1305 - 2.424 0.382 - 282.9 1 1 0 0.0025 12 0 0 0 1.39E+07 2.19E+06 - - - 4.1914 0.9997 221125_WJC_METTL3_EV_vs_WT_F10.09902.09902.2 3.38 18-Oct R.YPDGIISK[136.11]PK[136.11].N sp|Q86U44|MTA70_HUMAN 1 1132.6463 0 142102 9902 2 1132.647493 567.3304 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 8.5 2091.7 - 433201 - - - 1.0445 - 1.944 0.433 - 295.4 1 2 0 0.0012 10 0 0 0 4.50E+04 1.89E+08 - - - 4.0943 0.999 221125_WJC_METTL3_EV_vs_WT_F10.09903.09903.3 0.000299 Dec-68 K.QLGDSPAEDK[136.11]SSFK[136.11]PYSK[136.11].G sp|Q9H7S9|ZN703_HUMAN 1 2007.0011 1.49 142103 9903 3 2006.998226 670.0077 Zinc finger protein 703 OS=Homo sapiens OX=9606 GN=ZNF703 PE=1 SV=1 6.12 2091.9 - 364646 - - - -1.4499 - 2.124 0.385 - 135.4 1 2 1 -0.0029 18 0 0 0 8.21E+06 5.52E+06 - - - 4.7074 1 221125_WJC_METTL3_EV_vs_WT_F10.09907.09907.2 7.79E-10 30-Oct R.DGQVINETSQHHDDLE.- sp|P08670|VIME_HUMAN 1 1835.7922 - 142107 9907 2 1835.789514 918.9034 Vimentin OS=Homo sapiens OX=9606 GN=VIM PE=1 SV=4 4.28 2092.4 - 148280 - - - -1.4626 - 2.285 0.719 - 194.1 1 2 0 -0.0027 16 0 0 0 - - - - - 6.3823 0.9995 221125_WJC_METTL3_EV_vs_WT_F10.09920.09920.4 0.000138 12/108 R.LKTEEGEIDYSAEEGENRR.E "sp|Q8WVV9|HNRLL_HUMAN,tr|V9GYK2|V9GYK2_HUMAN,tr|C9IYN3|C9IYN3_HUMAN,tr|B7WPG3|B7WPG3_HUMAN" 4 2224.0244 1.16 142116 9920 4 2224.021399 557.0134 Heterogeneous nuclear ribonucleoprotein L-like OS=Homo sapiens OX=9606 GN=HNRNPLL PE=1 SV=1 4.31 2094 - 298329 - - - -1.3422 - 1.98 0.421 - 92.5 1 2 1 -0.003 19 0 0 0 5.79E+06 5.01E+06 - - - 3.1206 0.958 221125_WJC_METTL3_EV_vs_WT_F10.09927.09927.2 1.66E-06 16-Sep Y.PDGIISK[136.11]PK[136.11].N sp|Q86U44|MTA70_HUMAN 1 969.583 0.01 142120 9927 2 969.580803 485.7988 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 9.01 2094.8 - 291654 - - - -2.2474 - 2.091 0.334 - 196.3 1 1 0 -0.0022 9 0 0 0 1.99E+05 2.88E+07 - - - 3.6413 1 221125_WJC_METTL3_EV_vs_WT_F10.09940.09940.3 3.12E-09 18/96 K.SGGGTGEEPGSQGLNGEAGPEDSTR[166.11].E sp|O15355|PPM1G_HUMAN 1 2355.0086 0.53 142129 9940 3 2355.003438 786.0102 Protein phosphatase 1G OS=Homo sapiens OX=9606 GN=PPM1G PE=1 SV=1 3.91 2096.5 - 481334 - - - -2.2021 - 3.215 0.72 - 295.1 1 2 0 -0.0052 25 0 0 0 5.60E+06 1.06E+07 - - - 9.2526 0.9998 221125_WJC_METTL3_EV_vs_WT_F10.09950.09950.4 2.30E-08 20/84 K.DTGKTPVEPEVAIHR.L "sp|P60866|RS20_HUMAN,tr|E5RJX2|E5RJX2_HUMAN,tr|E5RIP1|E5RIP1_HUMAN" 3 1647.858 1.35 142134 9950 4 1647.856475 412.9718 40S ribosomal protein S20 OS=Homo sapiens OX=9606 GN=RPS20 PE=1 SV=1 5.45 2097.8 - 695628 - - - -0.9461 - 3.175 0.456 - 277.9 1 2 1 -0.0016 15 0 0 0 5.38E+08 3.99E+08 - - - 3.608 0.9993 221125_WJC_METTL3_EV_vs_WT_F10.09955.09955.3 4.13E-07 17/56 K.DTGK[136.11]TPVEPEVAIHR[166.11].L "sp|P60866|RS20_HUMAN,tr|E5RJX2|E5RJX2_HUMAN,tr|E5RIP1|E5RIP1_HUMAN" 3 1665.8805 1.4 142137 9955 3 1665.87365 556.3008 40S ribosomal protein S20 OS=Homo sapiens OX=9606 GN=RPS20 PE=1 SV=1 5.45 2098.4 - 863412 - - - -4.1143 - 3.178 0.511 - 510.3 1 2 1 -0.0069 15 0 0 0 4.47E+08 3.18E+08 - - - 7.2523 1 221125_WJC_METTL3_EV_vs_WT_F10.09960.09960.3 2.45E-09 19/68 R.GSSYGVTSTESYKETLHK.T sp|P98175|RBM10_HUMAN 1 1972.9378 4.08 142140 9960 3 1972.934229 658.6532 RNA-binding protein 10 OS=Homo sapiens OX=9606 GN=RBM10 PE=1 SV=3 6.75 2099 - 793035 - - - -1.8105 - 3.47 0.634 - 389.2 1 2 1 -0.0036 18 0 0 0 8.56E+07 2.10E+07 - - - 8.7056 0.9999 221125_WJC_METTL3_EV_vs_WT_F10.09962.09962.3 7.60E-09 21/56 K.DTGKTPVEPEVAIHR.L "sp|P60866|RS20_HUMAN,tr|E5RJX2|E5RJX2_HUMAN,tr|E5RIP1|E5RIP1_HUMAN" 3 1647.858 1.4 142142 9962 3 1647.8565 550.2933 40S ribosomal protein S20 OS=Homo sapiens OX=9606 GN=RPS20 PE=1 SV=1 5.45 2099.2 - 1.31E+06 - - - -0.9309 - 3.382 0.565 - 762.5 1 2 1 -0.0015 15 0 0 0 4.47E+08 3.18E+08 - - - 8.0182 0.9994 221125_WJC_METTL3_EV_vs_WT_F10.09968.09968.4 0.0576 16/84 K.DTGK[136.11]TPVEPEVAIHR[166.11].L "sp|P60866|RS20_HUMAN,tr|E5RJX2|E5RJX2_HUMAN,tr|E5RIP1|E5RIP1_HUMAN" 3 1665.8805 1.35 142145 9968 4 1665.877114 417.4774 40S ribosomal protein S20 OS=Homo sapiens OX=9606 GN=RPS20 PE=1 SV=1 5.45 2099.9 - 2.20E+06 - - - -2.035 - 3.125 0.41 - 266 1 2 1 -0.0034 15 0 0 0 5.38E+08 3.99E+08 - - - 3.2014 1 221125_WJC_METTL3_EV_vs_WT_F10.09980.09980.3 4.38E-09 19/68 R.GSSYGVTSTESYK[136.11]ETLHK[136.11].T sp|P98175|RBM10_HUMAN 1 1988.9662 4.08 142153 9980 3 1988.95995 663.996 RNA-binding protein 10 OS=Homo sapiens OX=9606 GN=RBM10 PE=1 SV=3 6.75 2101.3 - 1.60E+06 - - - -3.1428 - 3.536 0.649 - 487.4 1 2 1 -0.0063 18 0 0 0 8.56E+07 2.10E+07 - - - 8.919 0.9999 221125_WJC_METTL3_EV_vs_WT_F10.09981.09981.4 3.45E-05 18/102 R.GSSYGVTSTESYK[136.11]ETLHK[136.11].T sp|P98175|RBM10_HUMAN 1 1988.9662 2.66 142154 9981 4 1988.962024 498.2488 RNA-binding protein 10 OS=Homo sapiens OX=9606 GN=RBM10 PE=1 SV=3 6.75 2101.4 - 2.60E+06 - - - -2.1001 - 3.323 0.561 - 233.1 1 2 1 -0.0042 18 0 0 0 1.22E+08 4.57E+07 - - - 4.5192 0.9998 221125_WJC_METTL3_EV_vs_WT_F10.10049.10049.3 6.99E-07 17/60 R.K[136.11]VC[160.03]GDSDK[136.11]GFVVINQK[136.11].G sp|P40227|TCPZ_HUMAN 1 1816.9568 0.15 142177 10049 3 1816.95277 606.6595 T-complex protein 1 subunit zeta OS=Homo sapiens OX=9606 GN=CCT6A PE=1 SV=3 8.18 2110.9 - 4.89E+06 - - - -2.2009 - 2.688 0.531 - 270.6 1 2 1 -0.004 16 0 0 0 2.01E+07 1.38E+08 - - - 6.9961 1 221125_WJC_METTL3_EV_vs_WT_F10.10070.10070.3 1.53E-11 24/60 K.IDK[136.11]VNEIVETNR[166.11]PDSK[136.11].N sp|Q15008|PSMD6_HUMAN 1 1882.0006 0.75 142186 10070 3 1882.003351 628.3408 26S proteasome non-ATPase regulatory subunit 6 OS=Homo sapiens OX=9606 GN=PSMD6 PE=1 SV=1 4.78 2113.7 - 1.33E+06 - - - 1.4479 - 4.228 0.603 - 719.7 1 2 1 0.0027 16 0 0 0 3.83E+07 5.11E+07 - - - 8.9614 0.9997 221125_WJC_METTL3_EV_vs_WT_F10.10082.10082.4 2.96E-06 21/90 K.IDK[136.11]VNEIVETNR[166.11]PDSK[136.11].N sp|Q15008|PSMD6_HUMAN 1 1882.0006 0.79 142191 10082 4 1881.995506 471.5074 26S proteasome non-ATPase regulatory subunit 6 OS=Homo sapiens OX=9606 GN=PSMD6 PE=1 SV=1 4.78 2115.2 - 1.79E+06 - - - -2.7205 - 3.599 0.504 - 349.6 1 2 1 -0.0051 16 0 0 0 4.27E+07 5.39E+07 - - - 4.0625 1 221125_WJC_METTL3_EV_vs_WT_F10.10084.10084.3 2.25E-13 23/80 R.VSGAASEPSK[136.11]EEPQVEQLGSK[136.11].R sp|O95873|CF047_HUMAN 1 2172.0881 1.19 142193 10084 3 2172.084174 725.0366 Uncharacterized protein C6orf47 OS=Homo sapiens OX=9606 GN=C6orf47 PE=1 SV=2 4.49 2115.4 - 941116 - - - -1.8107 - 4.182 0.625 - 714.7 1 2 1 -0.0039 21 0 0 0 3.88E+07 3.26E+07 - - - 8.9373 0.9994 221125_WJC_METTL3_EV_vs_WT_F10.10091.10091.3 1.22E-06 15/76 K.K[136.11]GTENGVNGTLTSNVADSPR[166.11].N "sp|Q15629|TRAM1_HUMAN,tr|G3XAN4|G3XAN4_HUMAN" 2 2034.0097 0.97 142198 10091 3 2033.997834 679.0105 Translocating chain-associated membrane protein 1 OS=Homo sapiens OX=9606 GN=TRAM1 PE=1 SV=3 6.07 2116.2 - 349865 - - - -5.8245 - 3.441 0.491 - 270.2 1 2 0 -0.0118 20 0 0 0 2.08E+07 2.14E+07 - - - 7.0089 0.9999 221125_WJC_METTL3_EV_vs_WT_F10.10100.10100.4 3.19E-07 14/96 K.VHTEC[160.03]C[160.03]HGDLLEC[160.03]ADDR.A "sp|P02768|ALBU_HUMAN,tr|B7WNR0|B7WNR0_HUMAN,tr|H0YA55|H0YA55_HUMAN,tr|A0A0C4DGB6|A0A0C4DGB6_HUMAN,tr|D6RHD5|D6RHD5_HUMAN,tr|C9JKR2|C9JKR2_HUMAN" 6 2085.8303 25.99 142202 10100 4 2085.824601 522.4648 Albumin OS=Homo sapiens OX=9606 GN=ALB PE=1 SV=2 4.42 2117.3 - 1.26E+06 - - - -2.7121 - 2.506 0.459 - 138.7 1 2 0 -0.0057 17 0 0 0 5.63E+07 2.17E+06 - - - 3.5385 0.9919 221125_WJC_METTL3_EV_vs_WT_F10.10102.10102.3 0.12 Jul-44 R.SRAEAESWYQTK.Y "sp|P48668|K2C6C_HUMAN,sp|P04259|K2C6B_HUMAN,sp|O95678|K2C75_HUMAN,sp|P02538|K2C6A_HUMAN" 4 1454.679 9.93 142203 10102 3 1454.678084 485.9003 "Keratin, type II cytoskeletal 6C OS=Homo sapiens OX=9606 GN=KRT6C PE=1 SV=3" 5.86 2117.5 - 1.34E+06 - - - -0.6345 - 1.792 0.276 - 60 5 2 1 -0.0009 12 0 0 0 3.26E+07 3.28E+06 - - - 2.9103 1 221125_WJC_METTL3_EV_vs_WT_F10.10105.10105.3 1.35E-07 25/80 R.VSGAASEPSKEEPQVEQLGSK.R sp|O95873|CF047_HUMAN 1 2156.0597 1.19 142205 10105 3 2156.059981 719.6938 Uncharacterized protein C6orf47 OS=Homo sapiens OX=9606 GN=C6orf47 PE=1 SV=2 4.49 2117.8 - 1.40E+06 - - - 0.1271 - 4.222 0.597 - 844.6 1 2 1 0.0003 21 0 0 0 3.88E+07 3.26E+07 - - - 8.649 1 221125_WJC_METTL3_EV_vs_WT_F10.10106.10106.2 3.82E-16 21/36 K.SC[160.03]SGVEFSTSGSSNTDTGK[136.11].V "sp|P45880|VDAC2_HUMAN,tr|A2A3S1|A2A3S1_HUMAN,tr|Q5JSD1|Q5JSD1_HUMAN,tr|Q5JSD2|Q5JSD2_HUMAN,tr|A0A0A0MR02|A0A0A0MR02_HUMAN" 5 1914.7993 1.49 142206 10106 2 1914.795915 958.4069 Voltage-dependent anion-selective channel protein 2 OS=Homo sapiens OX=9606 GN=VDAC2 PE=1 SV=2 4.37 2118 - 687348 - - - -1.7495 - 4.387 0.785 - 1705.9 1 2 0 -0.0034 19 0 0 0 2.87E+08 1.92E+08 - - - 8.4733 1 221125_WJC_METTL3_EV_vs_WT_F10.10109.10109.3 1.15E-09 18/64 K.VHTEC[160.03]C[160.03]HGDLLEC[160.03]ADDR.A "sp|P02768|ALBU_HUMAN,tr|B7WNR0|B7WNR0_HUMAN,tr|H0YA55|H0YA55_HUMAN,tr|A0A0C4DGB6|A0A0C4DGB6_HUMAN,tr|D6RHD5|D6RHD5_HUMAN,tr|C9JKR2|C9JKR2_HUMAN" 6 2085.8303 999 142207 10109 3 2085.82374 696.284 Albumin OS=Homo sapiens OX=9606 GN=ALB PE=1 SV=2 4.42 2118.4 - 705970 - - - -3.1249 - 3.491 0.724 - 439.1 1 2 0 -0.0065 17 0 0 0 3.37E+07 0.00E+00 - - - 9.7684 1 221125_WJC_METTL3_EV_vs_WT_F10.10118.10118.2 6.46E-16 21/36 K.SC[160.03]SGVEFSTSGSSNTDTGK.V "sp|P45880|VDAC2_HUMAN,tr|A2A3S1|A2A3S1_HUMAN,tr|Q5JSD1|Q5JSD1_HUMAN,tr|Q5JSD2|Q5JSD2_HUMAN,tr|A0A0A0MR02|A0A0A0MR02_HUMAN" 5 1906.7851 1.5 142212 10118 2 1906.784003 954.3998 Voltage-dependent anion-selective channel protein 2 OS=Homo sapiens OX=9606 GN=VDAC2 PE=1 SV=2 4.37 2119.5 - 2.05E+06 - - - -0.557 - 4.49 0.785 - 1590.3 1 2 0 -0.0011 19 0 0 0 2.88E+08 1.92E+08 - - - 8.5311 0.9991 221125_WJC_METTL3_EV_vs_WT_F10.10119.10119.3 0.00159 15/52 K.EGLELPEDEEEK[136.11]K[136.11]K[136.11].Q "sp|Q58FG0|HS905_HUMAN,sp|P08238|HS90B_HUMAN,sp|Q58FF7|H90B3_HUMAN,sp|P07900|HS90A_HUMAN" 4 1695.8629 1.03 142213 10119 3 1695.866794 566.2949 Putative heat shock protein HSP 90-alpha A5 OS=Homo sapiens OX=9606 GN=HSP90AA5P PE=2 SV=1 4.31 2119.6 - 1.25E+06 - - - 2.2897 - 2.281 0.413 - 134.3 1 2 1 0.0039 14 0 0 0 4.43E+07 4.31E+07 - - - 5.3349 1 221125_WJC_METTL3_EV_vs_WT_F10.10120.10120.3 0.00176 25/60 K.RPELLTHSTTEVTQPR.T "sp|P78347|GTF2I_HUMAN,tr|A0A494C0Q7|A0A494C0Q7_HUMAN,tr|A0A494C1K3|A0A494C1K3_HUMAN" 3 1863.9803 1.51 142214 10120 3 1863.983451 622.334 General transcription factor II-I OS=Homo sapiens OX=9606 GN=GTF2I PE=1 SV=2 6.76 2119.7 - 1.02E+06 - - - 1.7039 - 4.27 0.558 - 1126.1 1 2 0 0.0032 16 0 0 0 7.02E+08 4.65E+08 - - - 8.4849 1 221125_WJC_METTL3_EV_vs_WT_F10.10126.10126.3 2.90E-08 14/48 K.YNIWC[160.03]STEHGNK[136.11]R[166.11].L sp|Q9Y5A9|YTHD2_HUMAN 1 1681.775 1.25 142218 10126 3 1681.770148 561.5989 YTH domain-containing family protein 2 OS=Homo sapiens OX=9606 GN=YTHDF2 PE=1 SV=2 8.21 2120.4 - 1.35E+06 - - - -2.8815 - 3.073 0.611 - 197.3 1 2 0 -0.0048 13 0 0 0 8.22E+07 6.58E+07 - - - 8.3945 1 221125_WJC_METTL3_EV_vs_WT_F10.10133.10133.3 1.88E-06 17/72 K.SC[160.03]SGVEFSTSGSSNTDTGK[136.11].V "sp|P45880|VDAC2_HUMAN,tr|A2A3S1|A2A3S1_HUMAN,tr|Q5JSD1|Q5JSD1_HUMAN,tr|Q5JSD2|Q5JSD2_HUMAN,tr|A0A0A0MR02|A0A0A0MR02_HUMAN" 5 1914.7993 1.51 142220 10133 3 1914.799992 639.2737 Voltage-dependent anion-selective channel protein 2 OS=Homo sapiens OX=9606 GN=VDAC2 PE=1 SV=2 4.37 2121.4 - 1.16E+06 - - - 0.3797 - 2.854 0.565 - 370.8 1 2 0 0.0007 19 0 0 0 8.23E+07 5.46E+07 - - - 7.4155 0.9999 221125_WJC_METTL3_EV_vs_WT_F10.10135.10135.4 0.00434 Nov-72 K.YNIWC[160.03]STEHGNK[136.11]R[166.11].L sp|Q9Y5A9|YTHD2_HUMAN 1 1681.775 1.11 142221 10135 4 1681.771299 421.451 YTH domain-containing family protein 2 OS=Homo sapiens OX=9606 GN=YTHDF2 PE=1 SV=2 8.21 2121.6 - 2.58E+06 - - - -2.1971 - 2.101 0.498 - 89.1 1 2 0 -0.0037 13 0 0 0 8.67E+07 7.84E+07 - - - 3.8348 1 221125_WJC_METTL3_EV_vs_WT_F10.10141.10141.4 1.13E-08 18/72 K.YNIWC[160.03]STEHGNKR.L sp|Q9Y5A9|YTHD2_HUMAN 1 1663.7525 1.11 142223 10141 4 1663.744664 416.9454 YTH domain-containing family protein 2 OS=Homo sapiens OX=9606 GN=YTHDF2 PE=1 SV=2 8.21 2122.4 - 2.05E+06 - - - -4.7237 - 3.015 0.63 - 295.7 1 2 0 -0.0079 13 0 0 0 8.67E+07 7.84E+07 - - - 5.1165 0.9999 221125_WJC_METTL3_EV_vs_WT_F10.10153.10153.4 4.56E-07 28/90 K.RPELLTHSTTEVTQPR.T "sp|P78347|GTF2I_HUMAN,tr|A0A494C0Q7|A0A494C0Q7_HUMAN,tr|A0A494C1K3|A0A494C1K3_HUMAN" 3 1863.9803 1.41 142225 10153 4 1863.974914 467.0023 General transcription factor II-I OS=Homo sapiens OX=9606 GN=GTF2I PE=1 SV=2 6.76 2124.3 - 3.53E+06 - - - -2.8761 - 4.094 0.534 - 785.9 1 2 0 -0.0054 16 0 0 0 3.29E+08 2.33E+08 - - - 4.369 1 221125_WJC_METTL3_EV_vs_WT_F10.10165.10165.3 1.71E-06 16/60 K.STAGDTHLGGEDFDNR[166.11].M "sp|P54652|HSP72_HUMAN,sp|P11142|HSP7C_HUMAN,tr|E9PKE3|E9PKE3_HUMAN,tr|E9PN89|E9PN89_HUMAN" 4 1700.7266 0.14 142228 10165 3 1700.722246 567.9161 Heat shock-related 70 kDa protein 2 OS=Homo sapiens OX=9606 GN=HSPA2 PE=1 SV=1 4.22 2126.1 - 3.69E+06 - - - -2.546 - 2.692 0.557 - 173.8 1 2 0 -0.0043 16 0 0 0 8.06E+07 5.69E+08 - - - 7.2897 1 221125_WJC_METTL3_EV_vs_WT_F10.10196.10196.3 1.13E-10 19/60 K.STAGDTHLGGEDFDNR.M "sp|P54652|HSP72_HUMAN,sp|P11142|HSP7C_HUMAN,tr|E9PKE3|E9PKE3_HUMAN,tr|E9PN89|E9PN89_HUMAN" 4 1690.7183 0.14 142236 10196 3 1690.716207 564.58 Heat shock-related 70 kDa protein 2 OS=Homo sapiens OX=9606 GN=HSPA2 PE=1 SV=1 4.22 2130.5 - 1.66E+06 - - - -1.2415 - 3.383 0.642 - 494.4 1 2 0 -0.0021 16 0 0 0 8.06E+07 5.69E+08 - - - 8.8243 1 221125_WJC_METTL3_EV_vs_WT_F10.10199.10199.3 1.97E-12 25/72 R.MREDYDSVEQDGDEPGPQR.S sp|Q9Y5S9|RBM8A_HUMAN 1 2221.9182 2.34 142238 10199 3 2221.91305 741.6467 RNA-binding protein 8A OS=Homo sapiens OX=9606 GN=RBM8A PE=1 SV=1 3.9 2130.8 - 2.21E+06 - - - -2.3196 - 4.649 0.804 - 708.6 1 2 1 -0.0052 19 0 0 0 1.74E+08 7.44E+07 - - - 11.2776 1 221125_WJC_METTL3_EV_vs_WT_F10.10201.10201.3 1.25E-14 24/72 R.MR[166.11]EDYDSVEQDGDEPGPQR[166.11].S sp|Q9Y5S9|RBM8A_HUMAN 1 2241.9347 2.34 142240 10201 3 2241.929653 748.3189 RNA-binding protein 8A OS=Homo sapiens OX=9606 GN=RBM8A PE=1 SV=1 3.9 2131 - 1.94E+06 - - - -2.2708 - 4.542 0.772 - 600.6 1 2 1 -0.0051 19 0 0 0 1.74E+08 7.44E+07 - - - 10.8637 0.9998 221125_WJC_METTL3_EV_vs_WT_F10.10232.10232.3 1.35E-06 16/60 K.ATAGDTHLGGEDFDNR[166.11].L "sp|P48741|HSP77_HUMAN,sp|P0DMV8|HS71A_HUMAN,sp|P34931|HS71L_HUMAN,sp|P0DMV9|HS71B_HUMAN,sp|P17066|HSP76_HUMAN,tr|Q53FA3|Q53FA3_HUMAN,tr|V9GZ37|V9GZ37_HUMAN,tr|A0A0G2JIW1|A0A0G2JIW1_HUMAN" 8 1684.7317 0.18 142253 10232 3 1684.723181 562.5845 Putative heat shock 70 kDa protein 7 OS=Homo sapiens OX=9606 GN=HSPA7 PE=5 SV=2 4.22 2134.7 - 2.30E+06 - - - -5.0334 - 3.147 0.541 - 367 1 2 0 -0.0085 16 0 0 0 7.09E+07 4.01E+08 - - - 7.5109 0.9999 221125_WJC_METTL3_EV_vs_WT_F10.10233.10233.3 2.38E-05 16/48 K.NNSDKDQSLGNWR.L sp|Q03252|LMNB2_HUMAN 1 1532.6968 1.37 142254 10233 3 1532.697403 511.9062 Lamin-B2 OS=Homo sapiens OX=9606 GN=LMNB2 PE=1 SV=4 5.96 2134.8 - 1.62E+06 - - - 0.4052 - 2.339 0.501 - 262.1 1 2 1 0.0006 13 0 0 0 4.59E+07 3.34E+07 - - - 6.4293 1 221125_WJC_METTL3_EV_vs_WT_F10.10252.10252.3 2.30E-06 16/60 K.ATAGDTHLGGEDFDNR.L "sp|P48741|HSP77_HUMAN,sp|P0DMV8|HS71A_HUMAN,sp|P34931|HS71L_HUMAN,sp|P0DMV9|HS71B_HUMAN,sp|P17066|HSP76_HUMAN,tr|Q53FA3|Q53FA3_HUMAN,tr|V9GZ37|V9GZ37_HUMAN,tr|A0A0G2JIW1|A0A0G2JIW1_HUMAN" 8 1674.7234 0.18 142260 10252 3 1674.724178 559.2484 Putative heat shock 70 kDa protein 7 OS=Homo sapiens OX=9606 GN=HSPA7 PE=5 SV=2 4.22 2137.5 - 1.06E+06 - - - 0.4699 - 3.429 0.641 - 394.3 1 2 0 0.0008 16 0 0 0 7.09E+07 4.00E+08 - - - 8.8481 0.9999 221125_WJC_METTL3_EV_vs_WT_F10.10253.10253.4 1.11E-07 24/120 R.TYVPALEQSADGHK[136.11]ETGAPSK[136.11].E sp|P98175|RBM10_HUMAN 1 2201.0935 2.76 142261 10253 4 2201.091663 551.2807 RNA-binding protein 10 OS=Homo sapiens OX=9606 GN=RBM10 PE=1 SV=3 5.41 2137.6 - 710832 - - - -0.8469 - 3.735 0.53 - 312.8 1 2 1 -0.0019 21 0 0 0 2.19E+08 7.94E+07 - - - 4.2743 1 221125_WJC_METTL3_EV_vs_WT_F10.10258.10258.4 4.05E-09 20/120 R.TYVPALEQSADGHKETGAPSK.E sp|P98175|RBM10_HUMAN 1 2185.0651 2.76 142263 10258 4 2185.060427 547.2736 RNA-binding protein 10 OS=Homo sapiens OX=9606 GN=RBM10 PE=1 SV=3 5.41 2138.2 - 4.43E+06 - - - -2.151 - 3.814 0.624 - 200.4 1 2 1 -0.0047 21 0 0 0 2.23E+08 8.07E+07 - - - 5.0986 1 221125_WJC_METTL3_EV_vs_WT_F10.10279.10279.3 7.28E-10 22/80 R.TYVPALEQSADGHKETGAPSK.E sp|P98175|RBM10_HUMAN 1 2185.0651 5.57 142270 10279 3 2185.062532 729.3623 RNA-binding protein 10 OS=Homo sapiens OX=9606 GN=RBM10 PE=1 SV=3 5.41 2140.9 - 949317 - - - -1.1876 - 3.114 0.642 - 154.6 1 2 1 -0.0026 21 0 0 0 4.59E+07 8.25E+06 - - - 8.4202 1 221125_WJC_METTL3_EV_vs_WT_F10.10291.10291.2 1.55E-08 Dec-38 R.SDSPVPTAPTSGGPK[136.11]PSTAS.A "sp|Q86U44|MTA70_HUMAN,tr|B4E349|B4E349_HUMAN,tr|F5H6D8|F5H6D8_HUMAN,tr|B4DTN4|B4DTN4_HUMAN" 4 1847.8992 0 142275 10291 2 1847.894212 924.9569 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 5.55 2142.3 - 774092 - - - -2.7193 - 2.695 0.625 - 233.4 1 1 0 -0.005 20 0 0 0 4.87E+04 3.84E+07 - - - 6.0931 0.9963 221125_WJC_METTL3_EV_vs_WT_F10.10292.10292.3 0.0158 Sep-72 R.TTSSANNPNLMYQDEC[160.03]DR[166.11]R[166.11].L "sp|Q92841|DDX17_HUMAN,tr|A0A5H1ZRQ2|A0A5H1ZRQ2_HUMAN,tr|A0A1X7SBZ2|A0A1X7SBZ2_HUMAN" 3 2290.981 1.1 142276 10292 3 2290.982835 764.6676 Probable ATP-dependent RNA helicase DDX17 OS=Homo sapiens OX=9606 GN=DDX17 PE=1 SV=2 4.56 2142.5 - 795695 - - - 0.8084 - 1.368 0.28 - 58.9 1 2 0 0.0019 19 0 0 0 4.70E+07 4.28E+07 - - - 2.431 0.9992 221125_WJC_METTL3_EV_vs_WT_F10.10297.10297.3 5.73E-05 Oct-52 K.HC[160.03]DKAEFFSSENVK.V sp|Q96EU7|C1GLC_HUMAN 1 1696.7515 1.75 142278 10297 3 1696.746401 566.5911 C1GALT1-specific chaperone 1 OS=Homo sapiens OX=9606 GN=C1GALT1C1 PE=1 SV=1 5.45 2143.1 - 347424 - - - -3.0169 - 1.908 0.516 - 39.6 1 2 1 -0.0051 14 0 0 0 4.99E+06 2.85E+06 - - - 6.0084 0.9999 221125_WJC_METTL3_EV_vs_WT_F10.10298.10298.3 0.00614 Oct-40 M.SDTWSSIQAHK[136.11].K "sp|Q86U44|MTA70_HUMAN,tr|B4E349|B4E349_HUMAN,tr|F5H6D8|F5H6D8_HUMAN,tr|B4DTN4|B4DTN4_HUMAN" 4 1266.6084 0.01 142279 10298 3 1266.60743 423.2101 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 6.46 2143.3 - 360129 - - - -0.7777 - 2.01 0.385 - 193 1 2 0 -0.001 11 0 0 0 5.54E+04 7.78E+06 - - - 4.8154 0.9998 221125_WJC_METTL3_EV_vs_WT_F10.10299.10299.3 1.40E-10 17/80 R.TYVPALEQSADGHK[136.11]ETGAPSK[136.11].E sp|P98175|RBM10_HUMAN 1 2201.0935 5.56 142280 10299 3 2201.088002 734.7051 RNA-binding protein 10 OS=Homo sapiens OX=9606 GN=RBM10 PE=1 SV=3 5.41 2143.4 - 460745 - - - -2.5101 - 2.988 0.595 - 193 1 2 1 -0.0055 21 0 0 0 4.59E+07 8.25E+06 - - - 7.7964 0.9998 221125_WJC_METTL3_EV_vs_WT_F10.10301.10301.3 0.00159 Aug-36 R.K[136.11]QDSGHLDLR[166.11].N "sp|Q86U44|MTA70_HUMAN,tr|B4E349|B4E349_HUMAN,tr|F5H6D8|F5H6D8_HUMAN,tr|B4DTN4|B4DTN4_HUMAN" 4 1185.6221 0.01 142282 10301 3 1185.62101 396.2146 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 6.75 2143.7 - 270864 - - - -0.9236 - 1.79 0.405 - 93.3 1 2 0 -0.0011 10 0 0 0 7.44E+04 1.23E+07 - - - 4.7554 1 221125_WJC_METTL3_EV_vs_WT_F10.10304.10304.3 1.23E-11 24/60 K.KAVDQHNAEAQDIFGK.N "sp|P52732|KIF11_HUMAN,tr|A0A7I2YQY4|A0A7I2YQY4_HUMAN,tr|A0A7I2V3A9|A0A7I2V3A9_HUMAN" 3 1769.8697 5.04 142283 10304 3 1769.873227 590.9638 Kinesin-like protein KIF11 OS=Homo sapiens OX=9606 GN=KIF11 PE=1 SV=2 5.38 2144.1 - 1.39E+06 - - - 2.0143 - 4.558 0.677 - 868.5 1 2 0 0.0036 16 0 0 0 2.46E+08 4.88E+07 - - - 9.979 0.9995 221125_WJC_METTL3_EV_vs_WT_F10.10312.10312.4 9.23E-12 17/90 K.KAVDQHNAEAQDIFGK.N "sp|P52732|KIF11_HUMAN,tr|A0A7I2YQY4|A0A7I2YQY4_HUMAN,tr|A0A7I2V3A9|A0A7I2V3A9_HUMAN" 3 1769.8697 5.83 142289 10312 4 1769.880192 443.4747 Kinesin-like protein KIF11 OS=Homo sapiens OX=9606 GN=KIF11 PE=1 SV=2 5.38 2144.9 - 1.10E+06 - - - 5.9496 - 3.714 0.558 - 324.2 1 2 0 0.0105 16 0 0 0 1.42E+08 2.43E+07 - - - 4.5421 1 221125_WJC_METTL3_EV_vs_WT_F10.10313.10313.4 7.87E-10 19/84 R.KPVLKPNKPLILANR.V "sp|Q96BP2|CHCH1_HUMAN,tr|A6NJX6|A6NJX6_HUMAN" 2 1700.0825 1.23 142290 10313 4 1700.08245 426.0279 Coiled-coil-helix-coiled-coil-helix domain-containing protein 1 OS=Homo sapiens OX=9606 GN=CHCHD1 PE=1 SV=1 11.26 2145 - 932508 - - - -0.0265 - 3.162 0.633 - 348.7 1 2 0 0 15 0 0 0 2.79E+08 2.26E+08 - - - 5.1475 0.9983 221125_WJC_METTL3_EV_vs_WT_F10.10314.10314.3 1.26E-05 13/72 R.TTSSANNPNLMYQDEC[160.03]DRR.L "sp|Q92841|DDX17_HUMAN,tr|A0A5H1ZRQ2|A0A5H1ZRQ2_HUMAN,tr|A0A1X7SBZ2|A0A1X7SBZ2_HUMAN" 3 2270.9644 1.09 142291 10314 3 2271.962104 757.9954 Probable ATP-dependent RNA helicase DDX17 OS=Homo sapiens OX=9606 GN=DDX17 PE=1 SV=2 4.56 2145.1 - 930982 - - - 439.3116 - 2.934 0.536 - 151.9 1 2 0 0.9977 19 0 0 0 4.68E+07 4.28E+07 - - - 6.8839 1 221125_WJC_METTL3_EV_vs_WT_F10.10318.10318.3 2.43E-10 Dec-68 K.TC[160.03]NTNPHLNALSTDSAC[160.03]R.R "sp|Q9NZB2|F120A_HUMAN,tr|A0A0C4DG79|A0A0C4DG79_HUMAN" 2 2030.8898 0.64 142295 10318 3 2030.889093 677.9706 Constitutive coactivator of PPAR-gamma-like protein 1 OS=Homo sapiens OX=9606 GN=FAM120A PE=1 SV=2 6.4 2145.6 - 176169 - - - -0.359 - 2.505 0.681 - 215.3 1 2 0 -0.0007 18 0 0 0 2.44E+06 3.80E+06 - - - 8.4189 0.9996 221125_WJC_METTL3_EV_vs_WT_F10.10321.10321.4 0.000126 Dec-72 R.DLLHPSLEEEK[136.11]K[136.11]K[136.11].H "sp|Q71UM5|RS27L_HUMAN,tr|H0YMV8|H0YMV8_HUMAN,tr|C9JLI6|C9JLI6_HUMAN" 3 1588.8887 0.61 142296 10321 4 1588.889447 398.2294 40S ribosomal protein S27-like OS=Homo sapiens OX=9606 GN=RPS27L PE=1 SV=3 5.53 2146.1 - 431876 - - - 0.4871 - 2.131 0.422 - 94.7 1 2 1 0.0008 13 0 0 0 6.09E+06 9.95E+06 - - - 3.1794 0.9999 221125_WJC_METTL3_EV_vs_WT_F10.10322.10322.4 1.17E-07 13/108 K.GVPHPEDDHSQVEGPESLR.- "sp|Q6P996|PDXD1_HUMAN,tr|H3BND4|H3BND4_HUMAN" 2 2083.9559 1.9 142297 10322 4 2083.962795 521.9963 Pyridoxal-dependent decarboxylase domain-containing protein 1 OS=Homo sapiens OX=9606 GN=PDXDC1 PE=1 SV=2 4.49 2146.2 - 235107 - - - 3.3038 - 2.656 0.508 - 89.4 1 2 0 0.0069 19 0 0 0 4.08E+06 2.15E+06 - - - 3.9762 0.9999 221125_WJC_METTL3_EV_vs_WT_F10.10323.10323.4 7.66E-08 15/108 R.VALENDDRSEEEKYTAVQR.N "sp|Q99700|ATX2_HUMAN,tr|F8W0B5|F8W0B5_HUMAN,tr|A0A5F9ZHW5|A0A5F9ZHW5_HUMAN,tr|A0A5F9ZHH4|A0A5F9ZHH4_HUMAN,tr|A0A5F9ZI57|A0A5F9ZI57_HUMAN,tr|A0A2R8YDM9|A0A2R8YDM9_HUMAN,tr|F8VQP2|F8VQP2_HUMAN,tr|A0A2R8Y5A6|A0A2R8Y5A6_HUMAN,tr|F8WB06|F8WB06_HUMAN,tr|A0A5F9ZH85|A0A5F9ZH85_HUMAN,tr|F8VRK6|F8VRK6_HUMAN,tr|V9GY86|V9GY86_HUMAN,tr|A0A2R8Y7E6|A0A2R8Y7E6_HUMAN,tr|A0A5F9ZHX3|A0A5F9ZHX3_HUMAN,tr|H0YH87|H0YH87_HUMAN,tr|A0A2R8Y7P6|A0A2R8Y7P6_HUMAN" 16 2251.0717 0.32 142298 10323 4 2251.074757 563.7752 Ataxin-2 OS=Homo sapiens OX=9606 GN=ATXN2 PE=1 SV=2 4.36 2146.3 - 1.20E+06 - - - 1.3718 - 3.13 0.538 - 176.7 1 2 2 0.0031 19 0 0 0 3.62E+07 1.12E+08 - - - 4.2939 0.9983 221125_WJC_METTL3_EV_vs_WT_F10.10325.10325.4 0.0316 Nov-72 R.DLLHPSLEEEKKK.H "sp|Q71UM5|RS27L_HUMAN,tr|H0YMV8|H0YMV8_HUMAN,tr|C9JLI6|C9JLI6_HUMAN" 3 1564.8461 0.61 142300 10325 4 1564.846005 392.2188 40S ribosomal protein S27-like OS=Homo sapiens OX=9606 GN=RPS27L PE=1 SV=3 5.53 2146.5 - 276310 - - - -0.0435 - 1.908 0.341 - 64.6 1 2 1 -0.0001 13 0 0 0 6.09E+06 9.95E+06 - - - 2.4336 1 221125_WJC_METTL3_EV_vs_WT_F10.10331.10331.3 4.91E-08 19/60 K.K[136.11]AVDQHNAEAQDIFGK[136.11].N "sp|P52732|KIF11_HUMAN,tr|A0A7I2YQY4|A0A7I2YQY4_HUMAN,tr|A0A7I2V3A9|A0A7I2V3A9_HUMAN" 3 1785.8981 5.05 142304 10331 3 1785.906848 596.3066 Kinesin-like protein KIF11 OS=Homo sapiens OX=9606 GN=KIF11 PE=1 SV=2 5.38 2147.2 - 2.02E+06 - - - 4.9197 - 3.702 0.606 - 479.9 1 2 0 0.0088 16 0 0 0 2.46E+08 4.87E+07 - - - 8.6523 1 221125_WJC_METTL3_EV_vs_WT_F10.10333.10333.4 1.04E-07 16/84 R.K[136.11]PVLK[136.11]PNK[136.11]PLILANR[166.11].V "sp|Q96BP2|CHCH1_HUMAN,tr|A6NJX6|A6NJX6_HUMAN" 2 1734.1334 1.23 142306 10333 4 1734.135417 434.5406 Coiled-coil-helix-coiled-coil-helix domain-containing protein 1 OS=Homo sapiens OX=9606 GN=CHCHD1 PE=1 SV=1 11.26 2147.4 - 1.71E+06 - - - 1.1833 - 2.654 0.673 - 240.7 1 2 0 0.0021 15 0 0 0 2.79E+08 2.26E+08 - - - 5.4325 1 221125_WJC_METTL3_EV_vs_WT_F10.10334.10334.3 2.22E-09 20/56 R.KPVLKPNKPLILANR.V "sp|Q96BP2|CHCH1_HUMAN,tr|A6NJX6|A6NJX6_HUMAN" 2 1700.0825 1.4 142307 10334 3 1700.086516 567.7014 Coiled-coil-helix-coiled-coil-helix domain-containing protein 1 OS=Homo sapiens OX=9606 GN=CHCHD1 PE=1 SV=1 11.26 2147.5 - 502697 - - - 2.3652 - 3.67 0.732 - 581.6 1 2 0 0.004 15 0 0 0 7.58E+07 5.42E+07 - - - 10.0926 1 221125_WJC_METTL3_EV_vs_WT_F10.10336.10336.3 0.000232 18/56 R.K[136.11]PVLK[136.11]PNK[136.11]PLILANR[166.11].V "sp|Q96BP2|CHCH1_HUMAN,tr|A6NJX6|A6NJX6_HUMAN" 2 1734.1334 1.4 142309 10336 3 1734.13781 579.0517 Coiled-coil-helix-coiled-coil-helix domain-containing protein 1 OS=Homo sapiens OX=9606 GN=CHCHD1 PE=1 SV=1 11.26 2147.8 - 438984 - - - 2.5632 - 2.75 0.653 - 382.3 1 2 0 0.0044 15 0 0 0 7.48E+07 5.34E+07 - - - 8.4587 0.9999 221125_WJC_METTL3_EV_vs_WT_F10.10337.10337.4 1.89E-05 10/108 K.GVPHPEDDHSQVEGPESLR[166.11].- "sp|Q6P996|PDXD1_HUMAN,tr|H3BND4|H3BND4_HUMAN" 2 2093.9642 1.9 142310 10337 4 2093.962961 524.4983 Pyridoxal-dependent decarboxylase domain-containing protein 1 OS=Homo sapiens OX=9606 GN=PDXDC1 PE=1 SV=2 4.49 2147.9 - 181205 - - - -0.5821 - 2.02 0.449 - 55.5 1 2 0 -0.0012 19 0 0 0 4.08E+06 2.15E+06 - - - 3.3716 1 221125_WJC_METTL3_EV_vs_WT_F10.10339.10339.3 2.86E-07 15/68 K.SSQSSVTVENASK[136.11]PDFTK[136.11].N "sp|Q8ND82|Z280C_HUMAN,tr|Q9UJJ2|Q9UJJ2_HUMAN" 2 1926.9506 1.26 142312 10339 3 1926.948778 643.3241 Zinc finger protein 280C OS=Homo sapiens OX=9606 GN=ZNF280C PE=1 SV=1 5.79 2148.2 - 132118 - - - -0.9201 - 3.204 0.539 - 300.5 1 2 0 -0.0018 18 0 0 0 9.53E+06 7.55E+06 - - - 7.4483 1 221125_WJC_METTL3_EV_vs_WT_F10.10340.10340.2 7.92E-07 17/30 K.KAVDQHNAEAQDIFGK.N "sp|P52732|KIF11_HUMAN,tr|A0A7I2YQY4|A0A7I2YQY4_HUMAN,tr|A0A7I2V3A9|A0A7I2V3A9_HUMAN" 3 1769.8697 19.62 142313 10340 2 1769.868553 885.9421 Kinesin-like protein KIF11 OS=Homo sapiens OX=9606 GN=KIF11 PE=1 SV=2 5.38 2148.3 - 121387 - - - -0.6266 - 3.277 0.626 - 798.5 1 2 0 -0.0011 16 0 0 0 3.48E+06 1.78E+05 - - - 6.5824 1 221125_WJC_METTL3_EV_vs_WT_F10.10346.10346.4 2.44E-10 18/90 K.K[136.11]AVDQHNAEAQDIFGK[136.11].N "sp|P52732|KIF11_HUMAN,tr|A0A7I2YQY4|A0A7I2YQY4_HUMAN,tr|A0A7I2V3A9|A0A7I2V3A9_HUMAN" 3 1785.8981 5.73 142317 10346 4 1785.901371 447.4818 Kinesin-like protein KIF11 OS=Homo sapiens OX=9606 GN=KIF11 PE=1 SV=2 5.38 2149.1 - 1.93E+06 - - - 1.8528 - 3.358 0.562 - 322.8 1 2 0 0.0033 16 0 0 0 1.39E+08 2.43E+07 - - - 4.5434 0.9994 221125_WJC_METTL3_EV_vs_WT_F10.10351.10351.3 8.06E-07 Nov-48 R.DLLHPSLEEEK[136.11]K[136.11]K[136.11].H "sp|Q71UM5|RS27L_HUMAN,tr|H0YMV8|H0YMV8_HUMAN,tr|C9JLI6|C9JLI6_HUMAN" 3 1588.8887 0.52 142322 10351 3 1588.892979 530.6368 40S ribosomal protein S27-like OS=Homo sapiens OX=9606 GN=RPS27L PE=1 SV=3 5.53 2149.8 - 317987 - - - 2.7101 - 2.309 0.48 - 117.7 1 2 1 0.0043 13 0 0 0 2.93E+06 5.62E+06 - - - 6.1592 0.9999 221125_WJC_METTL3_EV_vs_WT_F10.10354.10354.3 2.72E-07 15/64 K.ALEEETK[136.11]NHEAQIQDMR[166.11].Q sp|P35580|MYH10_HUMAN 1 2058.9759 0.7 142325 10354 3 2058.97738 687.3326 Myosin-10 OS=Homo sapiens OX=9606 GN=MYH10 PE=1 SV=3 4.57 2150.1 - 181155 - - - 0.7003 - 2.639 0.574 - 307.1 1 2 1 0.0014 17 0 0 0 1.61E+06 2.30E+06 - - - 7.3907 0.9978 221125_WJC_METTL3_EV_vs_WT_F10.10355.10355.3 0.00713 Aug-68 K.EAGQFGQGVHHTLEQAGK.E sp|Q6UWP8|SBSN_HUMAN 1 1892.9129 999 142326 10355 3 1892.91892 631.9783 Suprabasin OS=Homo sapiens OX=9606 GN=SBSN PE=1 SV=2 6.01 2150.3 - 171757 - - - 3.1681 - 1.81 0.341 - 42.9 1 2 0 0.006 18 0 0 0 5.38E+06 0.00E+00 - - - 3.8176 0.9957 221125_WJC_METTL3_EV_vs_WT_F10.10357.10357.2 0.129 12-Jun R.LASYLDK.V "sp|Q04695|K1C17_HUMAN,sp|Q99456|K1C12_HUMAN,sp|P13645|K1C10_HUMAN,sp|P02533|K1C14_HUMAN,sp|P08727|K1C19_HUMAN,sp|P35527|K1C9_HUMAN,sp|P08779|K1C16_HUMAN,sp|P19012|K1C15_HUMAN,tr|K7EPJ9|K7EPJ9_HUMAN,tr|C9JM50|C9JM50_HUMAN,tr|A0A1B0GVI3|A0A1B0GVI3_HUMAN,tr|A0A3B3ITG2|A0A3B3ITG2_HUMAN" 12 808.4331 135.31 142328 10357 2 808.434725 405.2238 "Keratin, type I cytoskeletal 17 OS=Homo sapiens OX=9606 GN=KRT17 PE=1 SV=2" 5.83 2150.5 - 104851 - - - 2.0472 - 1.32 0.265 - 116.3 1 2 0 0.0017 7 0 0 0 1.14E+07 8.41E+04 - - - 1.8775 0.9991 221125_WJC_METTL3_EV_vs_WT_F10.10380.10380.4 0.00222 18/102 K.LQQLK[136.11]DETGELSSADEK[136.11]R[166.11].Y sp|Q92900|RENT1_HUMAN 1 2072.0596 1.18 142345 10380 4 2072.062408 519.0222 Regulator of nonsense transcripts 1 OS=Homo sapiens OX=9606 GN=UPF1 PE=1 SV=2 4.51 2153.4 - 665801 - - - 1.3566 - 2.483 0.37 - 178.9 1 2 1 0.0028 18 0 0 0 6.17E+07 5.25E+07 - - - 2.7572 0.9938 221125_WJC_METTL3_EV_vs_WT_F10.10381.10381.3 2.49E-05 16/72 R.RLLEGEDAHLSSQQASGQS.Y sp|P08779|K1C16_HUMAN 1 2011.9559 1.37 142346 10381 3 2011.96093 671.6592 "Keratin, type I cytoskeletal 16 OS=Homo sapiens OX=9606 GN=KRT16 PE=1 SV=4" 4.65 2153.5 - 461430 - - - 2.4951 - 2.808 0.525 - 389.4 1 1 0 0.005 19 0 0 0 2.00E+07 1.46E+07 - - - 6.9284 0.9998 221125_WJC_METTL3_EV_vs_WT_F10.10393.10393.4 6.86E-06 13/96 K.LSHSDEKPFEC[160.03]PIC[160.03]NQR.F "sp|Q14119|VEZF1_HUMAN,tr|J3QSH4|J3QSH4_HUMAN,tr|J9JIC7|J9JIC7_HUMAN" 3 2115.9466 1.51 142354 10393 4 2115.955449 529.9939 Vascular endothelial zinc finger 1 OS=Homo sapiens OX=9606 GN=VEZF1 PE=1 SV=2 5.44 2155.1 - 402301 - - - 4.1778 - 2.56 0.546 - 97.5 1 2 0 0.0088 17 0 0 0 1.29E+07 8.54E+06 - - - 4.3023 0.9871 221125_WJC_METTL3_EV_vs_WT_F10.10396.10396.4 1.13E-05 20/90 G.GSRPHPLRPEAELAVR.A sp|Q8N5Z5|KCD17_HUMAN 1 1783.9805 3.25 142357 10396 4 1783.986297 447.0024 BTB\POZ domain-containing protein KCTD17 OS=Homo sapiens OX=9606 GN=KCTD17 PE=1 SV=3 9.52 2155.4 - 874171 - - - 3.222 - 3.077 0.509 - 327.9 1 1 0 0.0057 16 0 0 0 1.95E+08 6.02E+07 - - - 4.0507 0.9985 221125_WJC_METTL3_EV_vs_WT_F10.10398.10398.3 2.13E-05 17/68 K.LQQLKDETGELSSADEKR.Y sp|Q92900|RENT1_HUMAN 1 2046.0229 1.11 142359 10398 3 2046.032825 683.0149 Regulator of nonsense transcripts 1 OS=Homo sapiens OX=9606 GN=UPF1 PE=1 SV=2 4.51 2155.6 - 668059 - - - 4.8377 - 2.857 0.514 - 235.9 1 2 1 0.0099 18 0 0 0 2.54E+07 2.28E+07 - - - 6.8819 0.9683 221125_WJC_METTL3_EV_vs_WT_F10.10399.10399.4 639 2/108 P.GEGEEGSDDC[160.03]SEMC[160.03]DGEER.Q sp|Q13342|SP140_HUMAN 1 2146.6998 18.85 142360 10399 4 2146.700639 537.6822 Nuclear body protein SP140 OS=Homo sapiens OX=9606 GN=SP140 PE=1 SV=2 3.58 2155.7 - 169111 - - - 0.4109 - 0.308 0.439 - 2 1 1 0 0.0009 19 0 0 0 2.78E+07 1.47E+06 - - - 2.6484 1 221125_WJC_METTL3_EV_vs_WT_F10.10405.10405.3 2.41E-09 25/68 K.LQQLK[136.11]DETGELSSADEK[136.11]R[166.11].Y sp|Q92900|RENT1_HUMAN 1 2072.0596 1.11 142364 10405 3 2072.060384 691.6938 Regulator of nonsense transcripts 1 OS=Homo sapiens OX=9606 GN=UPF1 PE=1 SV=2 4.51 2156.6 - 594605 - - - 0.3798 - 4.535 0.633 - 825 1 2 1 0.0008 18 0 0 0 2.54E+07 2.28E+07 - - - 9.3617 1 221125_WJC_METTL3_EV_vs_WT_F10.10406.10406.4 2.73E-05 15/96 K.LSHSDEK[136.11]PFEC[160.03]PIC[160.03]NQR[166.11].F "sp|Q14119|VEZF1_HUMAN,tr|J3QSH4|J3QSH4_HUMAN,tr|J9JIC7|J9JIC7_HUMAN" 3 2133.9691 1.51 142365 10406 4 2133.969848 534.4995 Vascular endothelial zinc finger 1 OS=Homo sapiens OX=9606 GN=VEZF1 PE=1 SV=2 5.44 2156.7 - 469361 - - - 0.3604 - 2.166 0.488 - 132.3 1 2 0 0.0008 17 0 0 0 1.29E+07 8.54E+06 - - - 3.7417 0.9998 221125_WJC_METTL3_EV_vs_WT_F10.10407.10407.4 0.000561 Oct-78 R.LLEGEDAHLTQYKK.E "sp|Q04695|K1C17_HUMAN,tr|A0A3B3IS58|A0A3B3IS58_HUMAN,tr|F5GWP8|F5GWP8_HUMAN" 3 1643.8519 16.4 142366 10407 4 1643.853739 411.9702 "Keratin, type I cytoskeletal 17 OS=Homo sapiens OX=9606 GN=KRT17 PE=1 SV=2" 5.45 2156.9 - 289771 - - - 1.1272 - 1.399 0.392 - 36 1 2 0 0.0019 14 0 0 0 6.21E+06 3.78E+05 - - - 2.7597 0.9595 221125_WJC_METTL3_EV_vs_WT_F10.10413.10413.4 0.025 Oct-96 K.SSPVPYQDHDQPPVLKK.E "sp|Q8TEK3|DOT1L_HUMAN,tr|H7C2S2|H7C2S2_HUMAN" 2 1933.9898 2.44 142370 10413 4 1933.994998 484.5047 "Histone-lysine N-methyltransferase, H3 lysine-79 specific OS=Homo sapiens OX=9606 GN=DOT1L PE=1 SV=3" 6.46 2157.6 - 205043 - - - 2.6996 - 1.63 0.184 - 47.8 1 2 0 0.0052 17 0 0 0 6.06E+06 2.48E+06 - - - 0.9957 1 221125_WJC_METTL3_EV_vs_WT_F10.10415.10415.3 1.20E-05 Dec-64 K.LSHSDEK[136.11]PFEC[160.03]PIC[160.03]NQR[166.11].F "sp|Q14119|VEZF1_HUMAN,tr|J3QSH4|J3QSH4_HUMAN,tr|J9JIC7|J9JIC7_HUMAN" 3 2133.9691 1.58 142372 10415 3 2133.967044 712.3303 Vascular endothelial zinc finger 1 OS=Homo sapiens OX=9606 GN=VEZF1 PE=1 SV=2 5.44 2157.9 - 166293 - - - -0.9536 - 2.579 0.563 - 156.2 1 2 0 -0.002 17 0 0 0 4.87E+06 3.07E+06 - - - 7.2098 1 221125_WJC_METTL3_EV_vs_WT_F10.10425.10425.3 9.57E-07 16/64 K.LSHSDEKPFEC[160.03]PIC[160.03]NQR.F "sp|Q14119|VEZF1_HUMAN,tr|J3QSH4|J3QSH4_HUMAN,tr|J9JIC7|J9JIC7_HUMAN" 3 2115.9466 1.58 142378 10425 3 2115.939685 706.3228 Vascular endothelial zinc finger 1 OS=Homo sapiens OX=9606 GN=VEZF1 PE=1 SV=2 5.44 2159.2 - 224487 - - - -3.2723 - 3.017 0.656 - 269.3 1 2 0 -0.0069 17 0 0 0 4.87E+06 3.07E+06 - - - 8.6415 1 221125_WJC_METTL3_EV_vs_WT_F10.10427.10427.4 4.41E-06 15/102 K.EEAIEHNYGGHDDDLSVR[166.11].H "sp|Q93009|UBP7_HUMAN,tr|A0A669KBL1|A0A669KBL1_HUMAN,tr|F5H2X1|F5H2X1_HUMAN,tr|H3BND8|H3BND8_HUMAN" 4 2064.9012 1.19 142380 10427 4 2064.903503 517.2326 Ubiquitin carboxyl-terminal hydrolase 7 OS=Homo sapiens OX=9606 GN=USP7 PE=1 SV=2 4.29 2159.5 - 349278 - - - 1.093 - 3.032 0.6 - 234.8 1 2 0 0.0023 18 0 0 0 1.89E+07 1.58E+07 - - - 4.8277 1 221125_WJC_METTL3_EV_vs_WT_F10.10428.10428.3 5.24E-10 15/108 R.AAPSSEGDSC[160.03]DGVEATEGPGSADTEEPK.S "sp|P39880|CUX1_HUMAN,tr|A0A2R8Y852|A0A2R8Y852_HUMAN,tr|A0A2R8YDI1|A0A2R8YDI1_HUMAN" 3 2749.1145 1.78 142381 10428 3 2749.115339 917.3788 Homeobox protein cut-like 1 OS=Homo sapiens OX=9606 GN=CUX1 PE=1 SV=3 3.62 2159.6 - 279900 - - - 0.3205 - 3.312 0.757 - 188.1 1 2 0 0.0009 28 0 0 0 9.89E+06 5.54E+06 - - - 9.7347 1 221125_WJC_METTL3_EV_vs_WT_F10.10435.10435.4 2.81E-08 18/102 K.EEAIEHNYGGHDDDLSVR.H "sp|Q93009|UBP7_HUMAN,tr|A0A669KBL1|A0A669KBL1_HUMAN,tr|F5H2X1|F5H2X1_HUMAN,tr|H3BND8|H3BND8_HUMAN" 4 2054.893 1.19 142386 10435 4 2054.898196 514.7305 Ubiquitin carboxyl-terminal hydrolase 7 OS=Homo sapiens OX=9606 GN=USP7 PE=1 SV=2 4.29 2160.6 - 580665 - - - 2.5403 - 3.5 0.595 - 332.9 1 2 0 0.0052 18 0 0 0 1.89E+07 1.58E+07 - - - 4.8326 0.9969 221125_WJC_METTL3_EV_vs_WT_F10.10436.10436.4 0.0191 13/90 K.IELHGK[136.11]PIEVEHSVPK[136.11].R "sp|O00425|IF2B3_HUMAN,tr|F8WD15|F8WD15_HUMAN" 2 1827.0225 2.48 142387 10436 4 1827.022712 457.7629 Insulin-like growth factor 2 mRNA-binding protein 3 OS=Homo sapiens OX=9606 GN=IGF2BP3 PE=1 SV=2 6.02 2160.7 - 504570 - - - 0.0974 - 2.054 0.244 - 85.8 1 2 0 0.0002 16 0 0 0 1.13E+08 4.55E+07 - - - 1.6033 0.9977 221125_WJC_METTL3_EV_vs_WT_F10.10443.10443.3 3.03E-06 20/60 G.GSRPHPLRPEAELAVR.A sp|Q8N5Z5|KCD17_HUMAN 1 1783.9805 3.69 142392 10443 3 1783.981029 595.6675 BTB\POZ domain-containing protein KCTD17 OS=Homo sapiens OX=9606 GN=KCTD17 PE=1 SV=3 9.52 2161.7 - 755525 - - - 0.2691 - 3.043 0.497 - 210.4 1 1 0 0.0005 16 0 0 0 4.26E+07 1.15E+07 - - - 6.9363 1 221125_WJC_METTL3_EV_vs_WT_F10.10448.10448.3 7.91E-07 20/68 K.EEAIEHNYGGHDDDLSVR.H "sp|Q93009|UBP7_HUMAN,tr|A0A669KBL1|A0A669KBL1_HUMAN,tr|F5H2X1|F5H2X1_HUMAN,tr|H3BND8|H3BND8_HUMAN" 4 2054.893 1.05 142395 10448 3 2054.896313 685.9716 Ubiquitin carboxyl-terminal hydrolase 7 OS=Homo sapiens OX=9606 GN=USP7 PE=1 SV=2 4.29 2162.3 - 570415 - - - 1.6239 - 4.106 0.636 - 804.4 1 2 0 0.0033 18 0 0 0 6.99E+06 6.64E+06 - - - 9.147 0.9999 221125_WJC_METTL3_EV_vs_WT_F10.10454.10454.4 0.000137 13/96 R.ATSLGRPEEEEDELAHR.C "sp|P36551|HEM6_HUMAN,tr|D6RER6|D6RER6_HUMAN" 2 1937.9079 1.29 142399 10454 4 1937.90925 485.4843 "Oxygen-dependent coproporphyrinogen-III oxidase, mitochondrial OS=Homo sapiens OX=9606 GN=CPOX PE=1 SV=3" 4.41 2163.1 - 321361 - - - 0.6977 - 2.23 0.4 - 137.7 1 2 0 0.0014 17 0 0 0 8.20E+06 6.35E+06 - - - 2.9857 1 221125_WJC_METTL3_EV_vs_WT_F10.10458.10458.3 2.56E-06 16/60 K.IELHGKPIEVEHSVPK.R "sp|O00425|IF2B3_HUMAN,tr|F8WD15|F8WD15_HUMAN" 2 1810.9941 2.26 142401 10458 3 1810.992433 604.672 Insulin-like growth factor 2 mRNA-binding protein 3 OS=Homo sapiens OX=9606 GN=IGF2BP3 PE=1 SV=2 6.02 2163.6 - 735846 - - - -0.9393 - 2.86 0.513 - 223.6 1 2 0 -0.0017 16 0 0 0 2.69E+07 1.19E+07 - - - 6.9552 0.9997 221125_WJC_METTL3_EV_vs_WT_F10.10459.10459.4 0.000637 Nov-96 R.ATSLGR[166.11]PEEEEDELAHR[166.11].C "sp|P36551|HEM6_HUMAN,tr|D6RER6|D6RER6_HUMAN" 2 1957.9244 1.66 142402 10459 4 1957.924017 490.4884 "Oxygen-dependent coproporphyrinogen-III oxidase, mitochondrial OS=Homo sapiens OX=9606 GN=CPOX PE=1 SV=3" 4.41 2163.7 - 269025 - - - -0.215 - 2.142 0.362 - 109.3 1 2 0 -0.0004 17 0 0 0 7.47E+06 4.49E+06 - - - 2.6412 1 221125_WJC_METTL3_EV_vs_WT_F10.10460.10460.3 2.85E-10 18/68 K.EEAIEHNYGGHDDDLSVR[166.11].H "sp|Q93009|UBP7_HUMAN,tr|A0A669KBL1|A0A669KBL1_HUMAN,tr|F5H2X1|F5H2X1_HUMAN,tr|H3BND8|H3BND8_HUMAN" 4 2064.9012 1.05 142403 10460 3 2064.899938 689.3077 Ubiquitin carboxyl-terminal hydrolase 7 OS=Homo sapiens OX=9606 GN=USP7 PE=1 SV=2 4.29 2163.9 - 359230 - - - -0.6334 - 3.744 0.639 - 490.6 1 2 0 -0.0013 18 0 0 0 6.99E+06 6.64E+06 - - - 8.9512 0.9997 221125_WJC_METTL3_EV_vs_WT_F10.10464.10464.4 0.000932 14/90 K.IELHGKPIEVEHSVPK.R "sp|O00425|IF2B3_HUMAN,tr|F8WD15|F8WD15_HUMAN" 2 1810.9941 2.49 142405 10464 4 1810.993597 453.7558 Insulin-like growth factor 2 mRNA-binding protein 3 OS=Homo sapiens OX=9606 GN=IGF2BP3 PE=1 SV=2 6.02 2164.4 - 2.72E+06 - - - -0.2965 - 2.382 0.347 - 102 1 2 0 -0.0005 16 0 0 0 1.14E+08 4.59E+07 - - - 2.5519 0.9999 221125_WJC_METTL3_EV_vs_WT_F10.10465.10465.4 6.04E-05 15/126 R.SVAYNGPPASPSHETGAFAHAR[166.11].R "sp|Q9P0L2|MARK1_HUMAN,tr|A0A7I2V550|A0A7I2V550_HUMAN,tr|A0A087X0I6|A0A087X0I6_HUMAN,tr|A0A7I2YQC1|A0A7I2YQC1_HUMAN,tr|B4DIB3|B4DIB3_HUMAN" 5 2233.054 0.89 142406 10465 4 2233.050271 559.2708 Serine\threonine-protein kinase MARK1 OS=Homo sapiens OX=9606 GN=MARK1 PE=1 SV=2 6.66 2164.5 - 168271 - - - -1.6695 - 2.722 0.469 - 107.4 1 2 0 -0.0037 22 0 0 0 2.77E+06 3.11E+06 - - - 3.6348 0.9998 221125_WJC_METTL3_EV_vs_WT_F10.10468.10468.3 8.20E-07 14/84 K.EHYPVSSPSSPSPPAQPGGVSR.N "sp|O75179|ANR17_HUMAN,tr|H0YM23|H0YM23_HUMAN" 2 2219.0607 4.05 142409 10468 3 2219.072573 740.6942 Ankyrin repeat domain-containing protein 17 OS=Homo sapiens OX=9606 GN=ANKRD17 PE=1 SV=3 6.85 2164.9 - 171089 - - - 5.346 - 2.742 0.63 - 126.1 1 2 0 0.0119 22 0 0 0 1.74E+07 4.29E+06 - - - 7.952 0.9999 221125_WJC_METTL3_EV_vs_WT_F10.10476.10476.4 7.15E-08 18/114 R.GHLSRPEAQSLSPYTTSANR.A sp|O94776|MTA2_HUMAN 1 2171.0719 0.95 142412 10476 4 2171.075577 543.7753 Metastasis-associated protein MTA2 OS=Homo sapiens OX=9606 GN=MTA2 PE=1 SV=1 8.75 2165.9 - 292707 - - - 1.6738 - 3.293 0.467 - 321.6 1 2 0 0.0036 20 0 0 0 1.29E+07 1.36E+07 - - - 3.6882 1 221125_WJC_METTL3_EV_vs_WT_F10.10477.10477.4 0.000687 19/114 R.GHLSR[166.11]PEAQSLSPYTTSANR[166.11].A sp|O94776|MTA2_HUMAN 1 2191.0885 0.95 142413 10477 4 2191.08898 548.7794 Metastasis-associated protein MTA2 OS=Homo sapiens OX=9606 GN=MTA2 PE=1 SV=1 8.75 2166.1 - 266883 - - - 0.2268 - 3.713 0.501 - 327.4 1 2 0 0.0005 20 0 0 0 1.29E+07 1.36E+07 - - - 4.0251 0.9999 221125_WJC_METTL3_EV_vs_WT_F10.10481.10481.3 6.92E-06 15/76 R.GHLSR[166.11]PEAQSLSPYTTSANR[166.11].A sp|O94776|MTA2_HUMAN 1 2191.0885 0.96 142417 10481 3 2191.089211 731.3701 Metastasis-associated protein MTA2 OS=Homo sapiens OX=9606 GN=MTA2 PE=1 SV=1 8.75 2166.6 - 188893 - - - 0.3323 - 3.05 0.328 - 144.7 1 2 0 0.0007 20 0 0 0 6.01E+06 6.29E+06 - - - 4.902 0.9761 221125_WJC_METTL3_EV_vs_WT_F10.10486.10486.4 0.0506 12/114 K.LEVQATDR[166.11]EENK[136.11]QIALGTSK[136.11].L "sp|P11387|TOP1_HUMAN,tr|A0A7P0T852|A0A7P0T852_HUMAN" 2 2255.1968 0.52 142420 10486 4 2255.198958 564.8065 DNA topoisomerase 1 OS=Homo sapiens OX=9606 GN=TOP1 PE=1 SV=2 4.87 2167.2 - 460184 - - - 0.9746 - 2.148 0.214 - 93.9 1 2 2 0.0022 20 0 0 0 4.64E+06 8.99E+06 - - - 1.3436 0.9704 221125_WJC_METTL3_EV_vs_WT_F10.10488.10488.4 4.51E-05 10/114 T.C[160.03]VAASPHKDSVFLSC[160.03]SEDNR.L "sp|Q9BQA1|MEP50_HUMAN,tr|H0Y711|H0Y711_HUMAN" 2 2278.0107 3.15 142422 10488 4 2278.006889 570.5099 Methylosome protein 50 OS=Homo sapiens OX=9606 GN=WDR77 PE=1 SV=1 5.38 2167.5 - 177714 - - - -1.6576 - 2.127 0.471 - 68 1 1 1 -0.0038 20 0 0 0 9.56E+06 3.04E+06 - - - 3.5769 0.9999 221125_WJC_METTL3_EV_vs_WT_F10.10489.10489.3 3.50E-07 Dec-96 R.R[166.11]ASGLSTEGATGPSADTSGSELDGR[166.11].C sp|Q7Z628|ARHG8_HUMAN 1 2398.1111 1.03 142423 10489 3 2398.118691 800.3777 Neuroepithelial cell-transforming gene 1 protein OS=Homo sapiens OX=9606 GN=NET1 PE=1 SV=1 4.32 2167.6 - 154087 - - - 3.1533 - 2.738 0.571 - 152.3 1 2 0 0.0076 25 0 0 0 1.79E+06 1.74E+06 - - - 7.2213 1 221125_WJC_METTL3_EV_vs_WT_F10.10490.10490.3 7.91E-07 8/100 K.SQVPAAQPTAETK[136.11]PATAAVPTSQSVK[136.11].H sp|Q9UKY1|ZHX1_HUMAN 1 2580.373 1.24 142424 10490 3 2580.376309 861.1316 Zinc fingers and homeoboxes protein 1 OS=Homo sapiens OX=9606 GN=ZHX1 PE=1 SV=1 8.31 2167.7 - 108663 - - - 1.2839 - 2.011 0.557 - 37.5 1 2 0 0.0033 26 0 0 0 5.55E+06 4.47E+06 - - - 6.3564 0.9582 221125_WJC_METTL3_EV_vs_WT_F10.10495.10495.4 0.0168 8/114 K.LEVQATDREENKQIALGTSK.L "sp|P11387|TOP1_HUMAN,tr|A0A7P0T852|A0A7P0T852_HUMAN" 2 2229.1601 0.47 142427 10495 4 2229.171492 558.2973 DNA topoisomerase 1 OS=Homo sapiens OX=9606 GN=TOP1 PE=1 SV=2 4.87 2168.4 - 475240 - - - 5.1149 - 1.991 0.313 - 37.3 1 2 2 0.0114 20 0 0 0 4.23E+06 8.94E+06 - - - 2.1774 0.9491 221125_WJC_METTL3_EV_vs_WT_F10.10496.10496.4 0.000329 11/114 R.LSLQGHPTDLQTSNVKNEEK.L "sp|Q9P270|SLAI2_HUMAN,tr|D6RIF6|D6RIF6_HUMAN" 2 2237.1288 1.47 142428 10496 4 2237.141489 560.2895 SLAIN motif-containing protein 2 OS=Homo sapiens OX=9606 GN=SLAIN2 PE=1 SV=2 5.45 2168.6 - 480786 - - - 5.6765 - 2.459 0.314 - 72 1 2 1 0.0127 20 0 0 0 4.72E+06 3.21E+06 - - - 2.2563 0.9998 221125_WJC_METTL3_EV_vs_WT_F10.10500.10500.3 1.65E-09 15/96 R.RASGLSTEGATGPSADTSGSELDGR.C sp|Q7Z628|ARHG8_HUMAN 1 2378.0946 1.03 142432 10500 3 2378.106498 793.7055 Neuroepithelial cell-transforming gene 1 protein OS=Homo sapiens OX=9606 GN=NET1 PE=1 SV=1 4.32 2169 - 115940 - - - 5.0078 - 3.674 0.592 - 181.4 1 2 0 0.0119 25 0 0 0 1.79E+06 1.74E+06 - - - 8.1307 0.9999 221125_WJC_METTL3_EV_vs_WT_F10.10502.10502.3 0.000684 Nov-40 K.TPVEPEVAIHR.L "sp|P60866|RS20_HUMAN,tr|E5RJX2|E5RJX2_HUMAN,tr|E5RIP1|E5RIP1_HUMAN,tr|A0A7P0S5H5|A0A7P0S5H5_HUMAN" 4 1246.667 1.33 142434 10502 3 1246.669115 416.5629 40S ribosomal protein S20 OS=Homo sapiens OX=9606 GN=RPS20 PE=1 SV=1 5.37 2169.3 - 74282.1 - - - 1.7078 - 2.395 0.455 - 291.5 1 2 0 0.0021 11 0 0 0 3.65E+06 2.73E+06 - - - 6.0933 0.9998 221125_WJC_METTL3_EV_vs_WT_F10.10505.10505.3 6.34E-07 13/76 K.LEVQATDR[166.11]EENK[136.11]QIALGTSK[136.11].L "sp|P11387|TOP1_HUMAN,tr|A0A7P0T852|A0A7P0T852_HUMAN" 2 2255.1968 0.4 142435 10505 3 2255.20242 752.7395 DNA topoisomerase 1 OS=Homo sapiens OX=9606 GN=TOP1 PE=1 SV=2 4.87 2169.7 - 125662 - - - 2.5098 - 2.867 0.539 - 172.4 1 2 2 0.0057 20 0 0 0 5.58E+05 1.39E+06 - - - 7.103 0.9999 221125_WJC_METTL3_EV_vs_WT_F10.10508.10508.3 3.19E-06 Dec-84 K.EHYPVSSPSSPSPPAQPGGVSR[166.11].N "sp|O75179|ANR17_HUMAN,tr|H0YM23|H0YM23_HUMAN" 2 2229.069 4.05 142438 10508 3 2229.068928 744.0303 Ankyrin repeat domain-containing protein 17 OS=Homo sapiens OX=9606 GN=ANKRD17 PE=1 SV=3 6.85 2170.1 - 107661 - - - -0.0233 - 2.07 0.487 - 109.1 1 2 0 -0.0001 22 0 0 0 1.74E+07 4.29E+06 - - - 5.6944 0.9668 221125_WJC_METTL3_EV_vs_WT_F10.10519.10519.3 0.0192 Jul-40 K.SKWDEEWDKNK.S sp|Q14677|EPN4_HUMAN 1 1463.6681 1.53 142445 10519 3 1463.673302 488.8966 Clathrin interactor 1 OS=Homo sapiens OX=9606 GN=CLINT1 PE=1 SV=1 4.78 2171.6 - 230946 - - - 3.5486 - 1.426 0.321 - 37.9 1 2 2 0.0052 11 0 0 0 1.34E+08 8.78E+07 - - - 3.1255 1 221125_WJC_METTL3_EV_vs_WT_F10.10528.10528.3 5.07E-14 20/92 K.APPTLQAETATKPQATSAPSPAPK.Q "sp|Q96HA1|P121A_HUMAN,sp|A8CG34|P121C_HUMAN" 2 2359.2383 2.07 142451 10528 3 2359.246738 787.4201 Nuclear envelope pore membrane protein POM 121 OS=Homo sapiens OX=9606 GN=POM121 PE=1 SV=2 8.64 2172.8 - 218877 - - - 3.5596 - 4.231 0.669 - 425.1 1 2 0 0.0084 24 0 0 0 1.06E+07 5.10E+06 - - - 9.3466 0.9996 221125_WJC_METTL3_EV_vs_WT_F10.10529.10529.3 5.62E-07 14/40 K.SK[136.11]WDEEWDK[136.11]NK[136.11].S sp|Q14677|EPN4_HUMAN 1 1487.7107 1.53 142452 10529 3 1487.716056 496.9108 Clathrin interactor 1 OS=Homo sapiens OX=9606 GN=CLINT1 PE=1 SV=1 4.78 2173 - 497501 - - - 3.5948 - 2.784 0.556 - 162.5 1 2 2 0.0053 11 0 0 0 1.34E+08 8.78E+07 - - - 7.6461 1 221125_WJC_METTL3_EV_vs_WT_F10.10535.10535.3 7.86E-07 Nov-92 K.APPTLQAETATK[136.11]PQATSAPSPAPK[136.11].Q "sp|Q96HA1|P121A_HUMAN,sp|A8CG34|P121C_HUMAN" 2 2375.2667 2.07 142456 10535 3 2375.272568 792.7629 Nuclear envelope pore membrane protein POM 121 OS=Homo sapiens OX=9606 GN=POM121 PE=1 SV=2 8.64 2173.8 - 168663 - - - 2.4536 - 2.429 0.587 - 84.1 1 2 0 0.0058 24 0 0 0 1.06E+07 5.10E+06 - - - 7.1441 0.959 221125_WJC_METTL3_EV_vs_WT_F10.10538.10538.3 0.0995 Aug-36 R.K[136.11]QDSGHLDLR[166.11].N "sp|Q86U44|MTA70_HUMAN,tr|B4E349|B4E349_HUMAN,tr|F5H6D8|F5H6D8_HUMAN,tr|B4DTN4|B4DTN4_HUMAN" 4 1185.6221 0.03 142458 10538 3 1185.627134 396.2146 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 6.75 2174.2 - 269424 - - - 4.2417 - 1.471 0.237 - 95.7 1 2 0 0.005 10 0 0 0 1.92E+05 6.80E+06 - - - 2.308 0.9997 221125_WJC_METTL3_EV_vs_WT_F10.10540.10540.3 5.13E-06 18/72 K.DSEKENQIPEEAGSSGLGK.A "sp|Q15004|PAF15_HUMAN,tr|H0YMA4|H0YMA4_HUMAN,tr|A0A0U1RQM0|A0A0U1RQM0_HUMAN,tr|H0YKX3|H0YKX3_HUMAN" 4 1973.9178 0.8 142459 10540 3 1973.924527 658.9799 PCNA-associated factor OS=Homo sapiens OX=9606 GN=PCLAF PE=1 SV=1 4.25 2174.4 - 246133 - - - 3.411 - 2.912 0.573 - 385.8 1 2 1 0.0067 19 0 0 0 9.13E+06 1.14E+07 - - - 7.5524 1 221125_WJC_METTL3_EV_vs_WT_F10.10547.10547.4 1.56E-06 19/84 R.KPVLKPNKPLILANR.V "sp|Q96BP2|CHCH1_HUMAN,tr|A6NJX6|A6NJX6_HUMAN" 2 1700.0825 1.23 142464 10547 4 1700.08994 426.0279 Coiled-coil-helix-coiled-coil-helix domain-containing protein 1 OS=Homo sapiens OX=9606 GN=CHCHD1 PE=1 SV=1 11.26 2175.5 - 1.10E+06 - - - 4.3792 - 2.928 0.714 - 299 1 2 0 0.0074 15 0 0 0 2.78E+08 2.26E+08 - - - 5.823 0.8982 221125_WJC_METTL3_EV_vs_WT_F10.10548.10548.3 3.94E-06 14/56 T.KKITESVAETAQTIK.K sp|Q96A49|SYAP1_HUMAN 1 1645.9251 1.23 142465 10548 3 1645.932205 549.649 Synapse-associated protein 1 OS=Homo sapiens OX=9606 GN=SYAP1 PE=1 SV=1 8.5 2175.6 - 608532 - - - 4.3465 - 2.554 0.529 - 344.4 1 1 1 0.0072 15 0 0 0 1.28E+07 1.04E+07 - - - 6.8825 0.9924 221125_WJC_METTL3_EV_vs_WT_F10.10555.10555.2 0.0017 20-Nov K.SKWDEEWDKNK.S sp|Q14677|EPN4_HUMAN 1 1463.6681 1.66 142470 10555 2 1463.672696 732.8413 Clathrin interactor 1 OS=Homo sapiens OX=9606 GN=CLINT1 PE=1 SV=1 4.78 2176.6 - 159000 - - - 3.1346 - 2.118 0.487 - 289.1 1 2 2 0.0046 11 0 0 0 4.36E+06 2.62E+06 - - - 4.6667 0.9984 221125_WJC_METTL3_EV_vs_WT_F10.10567.10567.3 3.70E-07 16/72 K.SAIKDAEEDDDTGGINLHK.A "sp|Q13206|DDX10_HUMAN,tr|E9PIF2|E9PIF2_HUMAN" 2 2026.9443 0.64 142480 10567 3 2026.955185 676.6554 Probable ATP-dependent RNA helicase DDX10 OS=Homo sapiens OX=9606 GN=DDX10 PE=1 SV=2 4.23 2178.1 - 203340 - - - 5.3489 - 2.951 0.554 - 234.8 1 2 1 0.0108 19 0 0 0 3.57E+06 5.56E+06 - - - 7.3722 0.9999 221125_WJC_METTL3_EV_vs_WT_F10.10572.10572.3 4.89E-10 14/72 K.SAIK[136.11]DAEEDDDTGGINLHK[136.11].A "sp|Q13206|DDX10_HUMAN,tr|E9PIF2|E9PIF2_HUMAN" 2 2042.9727 0.63 142483 10572 3 2042.97581 681.9982 Probable ATP-dependent RNA helicase DDX10 OS=Homo sapiens OX=9606 GN=DDX10 PE=1 SV=2 4.23 2178.8 - 216771 - - - 1.5012 - 3.132 0.624 - 240.9 1 2 1 0.0031 19 0 0 0 3.77E+06 6.02E+06 - - - 8.301 0.9995 221125_WJC_METTL3_EV_vs_WT_F10.10574.10574.3 0.000202 13/40 R.KNHEEEMLALR.G "sp|P08779|K1C16_HUMAN,tr|K7ENW6|K7ENW6_HUMAN" 2 1368.682 6.1 142485 10574 3 1368.688519 457.2346 "Keratin, type I cytoskeletal 16 OS=Homo sapiens OX=9606 GN=KRT16 PE=1 SV=4" 5.5 2179 - 338041 - - - 4.7747 - 2.546 0.448 - 278.7 1 2 0 0.0065 11 0 0 0 7.05E+06 1.16E+06 - - - 6.1878 1 221125_WJC_METTL3_EV_vs_WT_F10.10578.10578.4 5.00E-07 13/84 R.K[136.11]PVLK[136.11]PNK[136.11]PLILANR[166.11].V "sp|Q96BP2|CHCH1_HUMAN,tr|A6NJX6|A6NJX6_HUMAN" 2 1734.1334 1.23 142487 10578 4 1734.139919 434.5406 Coiled-coil-helix-coiled-coil-helix domain-containing protein 1 OS=Homo sapiens OX=9606 GN=CHCHD1 PE=1 SV=1 11.26 2179.6 - 581639 - - - 3.7794 - 2.549 0.644 - 157.4 1 2 0 0.0066 15 0 0 0 2.79E+08 2.26E+08 - - - 5.1644 0.9064 221125_WJC_METTL3_EV_vs_WT_F10.10580.10580.2 0.00105 May-36 R.SDSPVPTAPTSGGPK[136.11]PSTA.S "sp|Q86U44|MTA70_HUMAN,tr|B4E349|B4E349_HUMAN,tr|F5H6D8|F5H6D8_HUMAN,tr|B4DTN4|B4DTN4_HUMAN" 4 1760.8672 0.001 142489 10580 2 1760.872932 881.4409 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 5.55 2179.8 - 81459 - - - 3.2507 - 1.395 0.497 - 44.9 1 1 0 0.0057 19 0 0 0 0.00E+00 7.04E+06 - - - 3.5285 0.9987 221125_WJC_METTL3_EV_vs_WT_F10.10585.10585.4 0.000526 12/108 K.SAIK[136.11]DAEEDDDTGGINLHK[136.11].A "sp|Q13206|DDX10_HUMAN,tr|E9PIF2|E9PIF2_HUMAN" 2 2042.9727 0.58 142492 10585 4 2042.978085 511.7505 Probable ATP-dependent RNA helicase DDX10 OS=Homo sapiens OX=9606 GN=DDX10 PE=1 SV=2 4.23 2180.5 - 326893 - - - 2.6148 - 1.999 0.408 - 86.7 1 2 1 0.0053 19 0 0 0 5.72E+06 9.94E+06 - - - 3.0101 0.9999 221125_WJC_METTL3_EV_vs_WT_F10.10586.10586.3 5.13E-07 14/72 K.GNEKEDAAGTSGLGELNSR.E "sp|Q5T3I0|GPTC4_HUMAN,tr|F8W895|F8W895_HUMAN,tr|A0A0A0MRK1|A0A0A0MRK1_HUMAN,tr|E9PAV9|E9PAV9_HUMAN" 4 1903.8872 1.13 142493 10586 3 1903.890261 635.6363 G patch domain-containing protein 4 OS=Homo sapiens OX=9606 GN=GPATCH4 PE=1 SV=2 4.41 2180.6 - 207580 - - - 1.6277 - 2.883 0.567 - 182.5 1 2 1 0.0031 19 0 0 0 6.46E+06 5.69E+06 - - - 7.462 0.9998 221125_WJC_METTL3_EV_vs_WT_F10.10592.10592.4 2.29E-08 18/126 K.VTSAVVGPSHEVQEQSSGPFKK.Q "sp|Q2KHR3|QSER1_HUMAN,tr|A0A3B3IRW6|A0A3B3IRW6_HUMAN" 2 2297.1652 7.99 142497 10592 4 2297.175633 575.2986 Glutamine and serine-rich protein 1 OS=Homo sapiens OX=9606 GN=QSER1 PE=1 SV=3 6.73 2181.5 - 640800 - - - 4.5526 - 3.689 0.555 - 204.2 1 2 0 0.0105 22 0 0 0 2.64E+07 3.31E+06 - - - 4.4809 0.9999 221125_WJC_METTL3_EV_vs_WT_F10.10593.10593.3 2.24E-10 18/56 K.KVLHFDQVTENTTGK.A sp|P29508|SPB3_HUMAN 1 1715.8842 2.53 142498 10593 3 1715.890262 572.9687 Serpin B3 OS=Homo sapiens OX=9606 GN=SERPINB3 PE=1 SV=2 6.75 2181.6 - 431322 - - - 3.5043 - 3.681 0.583 - 577.7 1 2 0 0.006 15 0 0 0 8.86E+06 3.50E+06 - - - 8.4387 0.9992 221125_WJC_METTL3_EV_vs_WT_F10.10595.10595.3 4.83E-05 Oct-72 K.GNEK[136.11]EDAAGTSGLGELNSR[166.11].E "sp|Q5T3I0|GPTC4_HUMAN,tr|F8W895|F8W895_HUMAN,tr|A0A0A0MRK1|A0A0A0MRK1_HUMAN,tr|E9PAV9|E9PAV9_HUMAN" 4 1921.9096 1.01 142500 10595 3 1921.916107 641.6438 G patch domain-containing protein 4 OS=Homo sapiens OX=9606 GN=GPATCH4 PE=1 SV=2 4.41 2181.9 - 211410 - - - 3.369 - 2.253 0.514 - 83.4 1 2 1 0.0065 19 0 0 0 6.56E+06 6.50E+06 - - - 6.2644 0.7757 221125_WJC_METTL3_EV_vs_WT_F10.10604.10604.3 0.0555 Jun-64 R.DKEQC[160.03]AEENIPASSLNK.G "sp|Q9UL03|INT6_HUMAN,tr|B3KQH5|B3KQH5_HUMAN,tr|G5E9X1|G5E9X1_HUMAN" 3 1931.8895 1.25 142507 10604 3 1931.898707 644.9704 Integrator complex subunit 6 OS=Homo sapiens OX=9606 GN=INTS6 PE=1 SV=1 4.41 2183 - 126181 - - - 4.7808 - 1.447 0.255 - 32.5 1 2 1 0.0092 17 0 0 0 1.51E+06 1.21E+06 - - - 2.3139 0.9998 221125_WJC_METTL3_EV_vs_WT_F10.10611.10611.3 0.00045 Nov-84 K.VTSAVVGPSHEVQEQSSGPFKK.Q "sp|Q2KHR3|QSER1_HUMAN,tr|A0A3B3IRW6|A0A3B3IRW6_HUMAN" 2 2297.1652 6.61 142512 10611 3 2297.174046 766.729 Glutamine and serine-rich protein 1 OS=Homo sapiens OX=9606 GN=QSER1 PE=1 SV=3 6.73 2183.9 - 150323 - - - 3.8617 - 2.486 0.507 - 109.6 1 2 0 0.0089 22 0 0 0 3.83E+06 5.79E+05 - - - 6.3492 0.9975 221125_WJC_METTL3_EV_vs_WT_F10.10616.10616.4 2.49E-05 Nov-84 R.NDTK[136.11]EDVFVHQTAIK[136.11].R "sp|Q9Y2T7|YBOX2_HUMAN,sp|P67809|YBOX1_HUMAN,sp|P16989|YBOX3_HUMAN,tr|H0Y449|H0Y449_HUMAN,tr|A0A0D9SEI8|A0A0D9SEI8_HUMAN" 5 1759.9076 1.1 142515 10616 4 1759.914679 440.9842 Y-box-binding protein 2 OS=Homo sapiens OX=9606 GN=YBX2 PE=1 SV=2 5.38 2184.6 - 391098 - - - 4.0428 - 1.721 0.439 - 65.9 1 2 1 0.0071 15 0 0 0 1.44E+07 1.31E+07 - - - 3.2393 0.9959 221125_WJC_METTL3_EV_vs_WT_F10.10617.10617.3 2.14E-06 12/100 R.EK[136.11]GSVGAVPSGTSPGGVATTAAAGSR[166.11].H sp|Q6ZNB6|NFXL1_HUMAN 1 2289.168 0.65 142516 10617 3 2289.182159 764.0633 NF-X1-type zinc finger protein NFXL1 OS=Homo sapiens OX=9606 GN=NFXL1 PE=1 SV=2 8.85 2184.8 - 125187 - - - 6.1974 - 2.577 0.544 - 118.3 1 2 1 0.0142 26 0 0 0 2.01E+06 3.09E+06 - - - 6.779 0.9994 221125_WJC_METTL3_EV_vs_WT_F10.10628.10628.3 5.78E-10 17/56 R.NDTK[136.11]EDVFVHQTAIK[136.11].R "sp|Q9Y2T7|YBOX2_HUMAN,sp|P67809|YBOX1_HUMAN,sp|P16989|YBOX3_HUMAN,tr|H0Y449|H0Y449_HUMAN,tr|A0A0D9SEI8|A0A0D9SEI8_HUMAN" 5 1759.9076 1.58 142523 10628 3 1759.915133 587.6431 Y-box-binding protein 2 OS=Homo sapiens OX=9606 GN=YBX2 PE=1 SV=2 5.38 2186.2 - 415019 - - - 4.3008 - 3.305 0.553 - 352.6 1 2 1 0.0076 15 0 0 0 1.84E+07 1.16E+07 - - - 7.8226 0.9979 221125_WJC_METTL3_EV_vs_WT_F10.10629.10629.4 0.0101 11/120 K.INHSNNAIVK[136.11]PPEMTPQAAAK[136.11].E "sp|Q8WXA9|SREK1_HUMAN,tr|H0YC47|H0YC47_HUMAN" 2 2246.1812 1.68 142524 10629 4 2246.188016 562.5526 Splicing regulatory glutamine\lysine-rich protein 1 OS=Homo sapiens OX=9606 GN=SREK1 PE=1 SV=1 8.6 2186.4 - 168560 - - - 3.0185 - 1.67 0.325 - 44.9 1 2 0 0.0068 21 0 0 0 9.71E+06 5.79E+06 - - - 2.2225 0.9997 221125_WJC_METTL3_EV_vs_WT_F10.10631.10631.3 0.000211 Oct-44 K.LSAMMGAVAEK[136.11]K[136.11].G "sp|Q86U44|MTA70_HUMAN,tr|F5H6D8|F5H6D8_HUMAN,tr|H0YFV6|H0YFV6_HUMAN,tr|B4DTN4|B4DTN4_HUMAN" 4 1250.6698 0.01 142525 10631 3 1250.67402 417.8972 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 8.59 2186.6 - 161012 - - - 3.4022 - 2.037 0.47 - 123.3 1 2 0 0.0043 12 0 0 0 1.62E+04 2.79E+06 - - - 5.751 0.9996 221125_WJC_METTL3_EV_vs_WT_F10.10633.10633.4 0.00025 11/126 K.VTSAVVGPSHEVQEQSSGPFK[136.11]K[136.11].Q "sp|Q2KHR3|QSER1_HUMAN,tr|A0A3B3IRW6|A0A3B3IRW6_HUMAN" 2 2313.1936 7.39 142526 10633 4 2313.200262 579.3057 Glutamine and serine-rich protein 1 OS=Homo sapiens OX=9606 GN=QSER1 PE=1 SV=3 6.73 2186.8 - 254851 - - - 2.8908 - 1.966 0.415 - 37.9 1 2 0 0.0067 22 0 0 0 2.44E+07 3.31E+06 - - - 3.0575 0.9981 221125_WJC_METTL3_EV_vs_WT_F10.10655.10655.3 1.96E-05 Nov-68 K.EVFGDDSEISKESSGVKK.R sp|O43395|PRPF3_HUMAN 1 1939.9375 1.63 142542 10655 3 1939.946652 647.6531 U4\U6 small nuclear ribonucleoprotein Prp3 OS=Homo sapiens OX=9606 GN=PRPF3 PE=1 SV=2 4.51 2189.8 - 149834 - - - 4.7352 - 2.12 0.544 - 108.1 1 2 1 0.0092 18 0 0 0 2.59E+06 1.59E+06 - - - 6.4736 1 221125_WJC_METTL3_EV_vs_WT_F10.10664.10664.3 0.000274 7/112 R.EPTSSEQGGLEGSGSAAGEGK[136.11]PALSEEER[166.11].Q "sp|Q04323|UBXN1_HUMAN,tr|E9PJ81|E9PJ81_HUMAN,tr|E9PRQ7|E9PRQ7_HUMAN" 3 2863.3074 0.84 142549 10664 3 2863.308921 955.4431 UBX domain-containing protein 1 OS=Homo sapiens OX=9606 GN=UBXN1 PE=1 SV=2 4.12 2191.1 - 122842 - - - 0.5176 - 1.864 0.555 - 19.8 1 2 0 0.0015 29 0 0 0 2.85E+06 3.39E+06 - - - 6.16 0.9999 221125_WJC_METTL3_EV_vs_WT_F10.10666.10666.3 1.08E-06 Oct-76 R.GQVK[136.11]PSTSSQPILSAPGPTK[136.11].L "sp|Q9ULT8|HECD1_HUMAN,tr|G3V4V5|G3V4V5_HUMAN,tr|A0A087X2H1|A0A087X2H1_HUMAN,tr|H0YJP0|H0YJP0_HUMAN" 4 1995.0972 0.38 142551 10666 3 1995.100264 666.0397 E3 ubiquitin-protein ligase HECTD1 OS=Homo sapiens OX=9606 GN=HECTD1 PE=1 SV=3 10 2191.4 - 81626.1 - - - 1.5583 - 2.142 0.526 - 84.8 1 2 0 0.0031 20 0 0 0 6.80E+05 1.79E+06 - - - 6.2515 0.9996 221125_WJC_METTL3_EV_vs_WT_F10.10674.10674.3 5.36E-06 17/100 R.EKGSVGAVPSGTSPGGVATTAAAGSR.H sp|Q6ZNB6|NFXL1_HUMAN 1 2271.1455 0.65 142557 10674 3 2271.149493 758.0558 NF-X1-type zinc finger protein NFXL1 OS=Homo sapiens OX=9606 GN=NFXL1 PE=1 SV=2 8.85 2192.5 - 138331 - - - 1.7573 - 2.36 0.468 - 147.1 1 2 1 0.004 26 0 0 0 2.01E+06 3.09E+06 - - - 5.7321 0.9993 221125_WJC_METTL3_EV_vs_WT_F10.10682.10682.4 8.21E-05 10/102 K.EVFGDDSEISKESSGVKK.R sp|O43395|PRPF3_HUMAN 1 1939.9375 0.61 142563 10682 4 1939.94182 485.9916 U4\U6 small nuclear ribonucleoprotein Prp3 OS=Homo sapiens OX=9606 GN=PRPF3 PE=1 SV=2 4.51 2193.5 - 158399 - - - 2.2444 - 1.951 0.43 - 51.5 1 2 1 0.0044 18 0 0 0 4.33E+06 7.04E+06 - - - 3.1965 1 221125_WJC_METTL3_EV_vs_WT_F10.10683.10683.3 3.38E-07 14/112 R.EPTSSEQGGLEGSGSAAGEGKPALSEEER.Q "sp|Q04323|UBXN1_HUMAN,tr|E9PJ81|E9PJ81_HUMAN,tr|E9PRQ7|E9PRQ7_HUMAN" 3 2845.285 0.84 142564 10683 3 2845.286808 949.4356 UBX domain-containing protein 1 OS=Homo sapiens OX=9606 GN=UBXN1 PE=1 SV=2 4.12 2193.7 - 121738 - - - 0.6463 - 2.544 0.55 - 116.7 1 2 0 0.0018 29 0 0 0 2.85E+06 3.39E+06 - - - 6.8196 0.9948 221125_WJC_METTL3_EV_vs_WT_F10.10697.10697.3 8.85E-10 8/104 N.GVDGNGVGQSQAGSGSTPSEPHPVLEK.L sp|Q9Y5A9|YTHD2_HUMAN 1 2590.2259 2.11 142576 10697 3 2590.229345 864.4159 YTH domain-containing family protein 2 OS=Homo sapiens OX=9606 GN=YTHDF2 PE=1 SV=2 4.65 2195.4 - 139135 - - - 1.3157 - 2.181 0.526 - 43.1 1 1 0 0.0034 27 0 0 0 1.88E+06 8.93E+05 - - - 6.1974 1 221125_WJC_METTL3_EV_vs_WT_F10.10703.10703.3 3.44E-11 15/88 K.GQEADLEAGGEEVPEANGSAGKR.S sp|Q9NX58|LYAR_HUMAN 1 2270.0411 0.85 142580 10703 3 2270.048186 757.6876 Cell growth-regulating nucleolar protein OS=Homo sapiens OX=9606 GN=LYAR PE=1 SV=2 4.14 2196.3 - 247345 - - - 3.1229 - 3.232 0.646 - 124.6 1 2 0 0.0071 23 0 0 0 3.32E+06 3.91E+06 - - - 8.4923 0.9695 221125_WJC_METTL3_EV_vs_WT_F10.10705.10705.3 1.08E-05 Nov-76 K.KGTENGVNGTLTSNVADSPR.N "sp|Q15629|TRAM1_HUMAN,tr|G3XAN4|G3XAN4_HUMAN" 2 2015.9872 -1 142582 10705 3 2016.980771 673.003 Translocating chain-associated membrane protein 1 OS=Homo sapiens OX=9606 GN=TRAM1 PE=1 SV=3 6.07 2196.6 - 150388 - - - 492.8404 - 2.382 0.458 - 160.4 1 2 0 0.9936 20 0 0 0 0.00E+00 0.00E+00 - - - 5.4767 1 221125_WJC_METTL3_EV_vs_WT_F10.10709.10709.3 4.44E-09 23/88 K.GQEADLEAGGEEVPEANGSAGK[136.11]R[166.11].S sp|Q9NX58|LYAR_HUMAN 1 2288.0636 0.85 142584 10709 3 2288.056174 763.6951 Cell growth-regulating nucleolar protein OS=Homo sapiens OX=9606 GN=LYAR PE=1 SV=2 4.14 2197.1 - 320174 - - - -3.2311 - 3.529 0.622 - 332.1 1 2 0 -0.0074 23 0 0 0 3.32E+06 3.91E+06 - - - 8.4309 1 221125_WJC_METTL3_EV_vs_WT_F10.10712.10712.4 1.81E-07 15/90 R.EYEDNDEVHIEVHNPR.N "sp|Q9UKF6|CPSF3_HUMAN,tr|G5E9W3|G5E9W3_HUMAN" 2 1993.8766 1.18 142587 10712 4 1993.879229 499.4764 Cleavage and polyadenylation specificity factor subunit 3 OS=Homo sapiens OX=9606 GN=CPSF3 PE=1 SV=1 4.35 2197.4 - 458250 - - - 1.32 - 3.1 0.665 - 169.6 1 2 0 0.0026 16 0 0 0 2.26E+07 1.92E+07 - - - 5.412 0.9998 221125_WJC_METTL3_EV_vs_WT_F10.10713.10713.4 0.000171 13/84 R.QFQDAGHFDAENIKK.K "sp|Q13813|SPTN1_HUMAN,tr|A0A0D9SF54|A0A0D9SF54_HUMAN,tr|A0A0D9SGF6|A0A0D9SGF6_HUMAN" 3 1746.8325 1.15 142588 10713 4 1746.834866 437.7154 "Spectrin alpha chain, non-erythrocytic 1 OS=Homo sapiens OX=9606 GN=SPTAN1 PE=1 SV=3" 5.38 2197.5 - 328110 - - - 1.327 - 2.021 0.373 - 82.5 1 2 0 0.0023 15 0 0 0 7.62E+06 6.64E+06 - - - 2.7237 0.9965 221125_WJC_METTL3_EV_vs_WT_F10.10715.10715.4 0.0286 Jul-84 R.QFQDAGHFDAENIK[136.11]K[136.11].K "sp|Q13813|SPTN1_HUMAN,tr|A0A0D9SF54|A0A0D9SF54_HUMAN,tr|A0A0D9SGF6|A0A0D9SGF6_HUMAN" 3 1762.8609 1.12 142590 10715 4 1762.860083 441.7225 "Spectrin alpha chain, non-erythrocytic 1 OS=Homo sapiens OX=9606 GN=SPTAN1 PE=1 SV=3" 5.38 2197.8 - 267156 - - - -0.4907 - 1.13 0.262 - 20.3 1 2 0 -0.0009 15 0 0 0 8.00E+06 7.16E+06 - - - 1.5499 0.8259 221125_WJC_METTL3_EV_vs_WT_F10.10717.10717.3 0.489 Sep-60 R.R[166.11]K[136.11]PLFC[160.03]GNSEADQLGK[136.11].L "sp|P11802|CDK4_HUMAN,tr|F8VZZ0|F8VZZ0_HUMAN,tr|F8VZ51|F8VZ51_HUMAN" 3 1844.9413 0.2 142592 10717 3 1844.95067 615.9877 Cyclin-dependent kinase 4 OS=Homo sapiens OX=9606 GN=CDK4 PE=1 SV=2 8.2 2198.1 - 183489 - - - 5.0587 - 1.505 0.189 - 65.2 1 2 0 0.0093 16 0 0 0 5.58E+05 2.81E+06 - - - 1.6935 1 221125_WJC_METTL3_EV_vs_WT_F10.10718.10718.3 6.49E-08 Nov-60 R.EYEDNDEVHIEVHNPR.N "sp|Q9UKF6|CPSF3_HUMAN,tr|G5E9W3|G5E9W3_HUMAN" 2 1993.8766 1.19 142593 10718 3 1993.876625 665.6328 Cleavage and polyadenylation specificity factor subunit 3 OS=Homo sapiens OX=9606 GN=CPSF3 PE=1 SV=1 4.35 2198.2 - 107016 - - - 0.014 - 2.191 0.666 - 122.8 1 2 0 0 16 0 0 0 5.87E+06 4.94E+06 - - - 7.9778 0.9986 221125_WJC_METTL3_EV_vs_WT_F10.10723.10723.4 0.0165 Sep-96 R.SK[136.11]C[160.03]EELSGLHGQLQEAR[166.11].A "sp|Q9P2E9|RRBP1_HUMAN,tr|A0A087WVV2|A0A087WVV2_HUMAN,tr|F8W7S5|F8W7S5_HUMAN" 3 1958.9599 1.58 142596 10723 4 1958.962242 490.7472 Ribosome-binding protein 1 OS=Homo sapiens OX=9606 GN=RRBP1 PE=1 SV=5 5.47 2198.9 - 178683 - - - 1.1986 - 2.052 0.349 - 67.9 1 2 1 0.0023 17 0 0 0 8.71E+06 5.52E+06 - - - 2.5126 0.9844 221125_WJC_METTL3_EV_vs_WT_F10.10725.10725.3 0.0423 Sep-48 R.KKVEAQLQELQVK.F sp|P35579|MYH9_HUMAN 1 1539.8984 0.91 142598 10725 3 1539.901654 514.3068 Myosin-9 OS=Homo sapiens OX=9606 GN=MYH9 PE=1 SV=4 8.5 2199.1 - 324835 - - - 2.0859 - 1.733 0.262 - 125.2 1 2 1 0.0032 13 0 0 0 1.79E+07 1.95E+07 - - - 2.951 0.9994 221125_WJC_METTL3_EV_vs_WT_F10.10726.10726.3 8.97E-08 13/64 R.SK[136.11]C[160.03]EELSGLHGQLQEAR[166.11].A "sp|Q9P2E9|RRBP1_HUMAN,tr|A0A087WVV2|A0A087WVV2_HUMAN,tr|F8W7S5|F8W7S5_HUMAN" 3 1958.9599 1.44 142599 10726 3 1958.964948 653.9939 Ribosome-binding protein 1 OS=Homo sapiens OX=9606 GN=RRBP1 PE=1 SV=5 5.47 2199.3 - 204152 - - - 2.5799 - 2.579 0.458 - 133.5 1 2 1 0.0051 17 0 0 0 6.11E+06 4.25E+06 - - - 6.0383 1 221125_WJC_METTL3_EV_vs_WT_F10.10727.10727.3 2.89E-15 21/80 K.GPSHSGNPSHGTLGLSGTLGR.A sp|Q86XN7|PRSR1_HUMAN 1 1987.9824 1.86 142600 10727 3 1987.986177 663.6681 Proline and serine-rich protein 1 OS=Homo sapiens OX=9606 GN=PROSER1 PE=1 SV=2 9.76 2199.4 - 162151 - - - 1.8999 - 3.791 0.622 - 497.6 1 2 0 0.0038 21 0 0 0 4.17E+07 2.25E+07 - - - 8.6686 0.9925 221125_WJC_METTL3_EV_vs_WT_F10.10730.10730.3 0.00113 Dec-76 K.GAC[160.03]DKTDEGALHGAAEANFR.L sp|P31268|HXA7_HUMAN 1 2088.9283 3.21 142601 10730 3 2088.93957 697.3167 Homeobox protein Hox-A7 OS=Homo sapiens OX=9606 GN=HOXA7 PE=1 SV=3 4.75 2199.8 - 244277 - - - 5.3875 - 2.321 0.438 - 98.3 1 2 1 0.0113 20 0 0 0 3.95E+06 1.23E+06 - - - 5.4629 1 221125_WJC_METTL3_EV_vs_WT_F10.10731.10731.3 4.05E-08 Oct-64 K.QHLSNMEVQVASQSSQR.T sp|P12270|TPR_HUMAN 1 1927.917 0.33 142602 10731 3 1927.916638 643.6463 Nucleoprotein TPR OS=Homo sapiens OX=9606 GN=TPR PE=1 SV=3 6.75 2199.9 - 122481 - - - -0.1992 - 2.382 0.472 - 113.8 1 2 0 -0.0004 17 0 0 0 1.95E+06 5.91E+06 - - - 5.9949 1 221125_WJC_METTL3_EV_vs_WT_F10.10733.10733.3 6.44E-13 14/60 K.HDDSSEVANIEERPIK.A "sp|Q9HC77|CENPJ_HUMAN,tr|F6VUX8|F6VUX8_HUMAN" 2 1837.8806 2.04 142604 10733 3 1837.882272 613.6341 Centromere protein J OS=Homo sapiens OX=9606 GN=CENPJ PE=1 SV=2 4.5 2200.2 - 257834 - - - 0.8989 - 3.196 0.699 - 284.4 1 2 0 0.0017 16 0 0 0 3.99E+06 1.96E+06 - - - 9.314 1 221125_WJC_METTL3_EV_vs_WT_F10.10738.10738.4 6.05E-10 18/120 K.GPSHSGNPSHGTLGLSGTLGR.A sp|Q86XN7|PRSR1_HUMAN 1 1987.9824 1.8 142607 10738 4 1987.984386 498.0029 Proline and serine-rich protein 1 OS=Homo sapiens OX=9606 GN=PROSER1 PE=1 SV=2 9.76 2200.9 - 1.64E+06 - - - 0.999 - 3.126 0.598 - 227.1 1 2 0 0.002 21 0 0 0 8.62E+07 4.79E+07 - - - 4.8073 0.9999 221125_WJC_METTL3_EV_vs_WT_F10.10740.10740.4 5.12E-05 18/120 K.GPSHSGNPSHGTLGLSGTLGR[166.11].A sp|Q86XN7|PRSR1_HUMAN 1 1997.9907 1.8 142609 10740 4 1997.993291 500.5049 Proline and serine-rich protein 1 OS=Homo sapiens OX=9606 GN=PROSER1 PE=1 SV=2 9.76 2201.1 - 1.28E+06 - - - 1.3118 - 3.193 0.465 - 274.6 1 2 0 0.0026 21 0 0 0 8.61E+07 4.79E+07 - - - 3.6565 0.9998 221125_WJC_METTL3_EV_vs_WT_F10.10741.10741.3 1.44E-06 14/48 R.K[136.11]K[136.11]VEAQLQELQVK[136.11].F sp|P35579|MYH9_HUMAN 1 1563.941 0.91 142610 10741 3 1563.943474 522.321 Myosin-9 OS=Homo sapiens OX=9606 GN=MYH9 PE=1 SV=4 8.5 2201.2 - 1.08E+06 - - - 1.555 - 2.5 0.494 - 401.8 1 2 1 0.0024 13 0 0 0 1.79E+07 1.95E+07 - - - 6.5313 0.7843 221125_WJC_METTL3_EV_vs_WT_F10.10742.10742.4 0.000555 Oct-96 K.NFSYKDDDRYEQASDVR.A "sp|O00268|TAF4_HUMAN,tr|A0A0G2JRY5|A0A0G2JRY5_HUMAN" 2 2106.9243 0.83 142611 10742 4 2106.941204 527.7383 Transcription initiation factor TFIID subunit 4 OS=Homo sapiens OX=9606 GN=TAF4 PE=1 SV=2 4.36 2201.3 - 672125 - - - 8.0345 - 2.182 0.297 - 49.8 1 2 2 0.0169 17 0 0 0 1.37E+07 1.66E+07 - - - 2.0773 0.9998 221125_WJC_METTL3_EV_vs_WT_F10.10743.10743.4 0.000103 Nov-96 K.NFSYK[136.11]DDDR[166.11]YEQASDVR[166.11].A "sp|O00268|TAF4_HUMAN,tr|A0A0G2JRY5|A0A0G2JRY5_HUMAN" 2 2134.955 0.81 142612 10743 4 2134.955261 534.746 Transcription initiation factor TFIID subunit 4 OS=Homo sapiens OX=9606 GN=TAF4 PE=1 SV=2 4.36 2201.5 - 359350 - - - 0.1148 - 2.113 0.479 - 62.3 1 2 2 0.0002 17 0 0 0 1.38E+07 1.70E+07 - - - 3.6549 0.9894 221125_WJC_METTL3_EV_vs_WT_F10.10744.10744.4 0.0742 Aug-72 R.K[136.11]K[136.11]VEAQLQELQVK[136.11].F sp|P35579|MYH9_HUMAN 1 1563.941 0.83 142613 10744 4 1563.940479 391.9925 Myosin-9 OS=Homo sapiens OX=9606 GN=MYH9 PE=1 SV=4 8.5 2201.6 - 174340 - - - -0.36 - 1.528 0.261 - 30.1 1 2 1 -0.0006 13 0 0 0 3.29E+06 3.98E+06 - - - 1.6548 1 221125_WJC_METTL3_EV_vs_WT_F10.10747.10747.3 5.52E-13 17/92 K.LEAIEDDSVKETDSSSASAATPSK.K "sp|P54578|UBP14_HUMAN,tr|A6NJA2|A6NJA2_HUMAN" 2 2437.1344 1.01 142616 10747 3 2437.133241 813.3854 Ubiquitin carboxyl-terminal hydrolase 14 OS=Homo sapiens OX=9606 GN=USP14 PE=1 SV=3 4.02 2202 - 154705 - - - -0.4706 - 3.731 0.713 - 258.9 1 2 1 -0.0011 24 0 0 0 3.98E+06 3.95E+06 - - - 9.547 0.9999 221125_WJC_METTL3_EV_vs_WT_F10.10752.10752.3 5.79E-05 Oct-64 K.NFSYKDDDRYEQASDVR.A "sp|O00268|TAF4_HUMAN,tr|A0A0G2JRY5|A0A0G2JRY5_HUMAN" 2 2106.9243 2.62 142619 10752 3 2106.926104 703.3154 Transcription initiation factor TFIID subunit 4 OS=Homo sapiens OX=9606 GN=TAF4 PE=1 SV=2 4.36 2202.6 - 292536 - - - 0.8676 - 2.115 0.545 - 91.3 1 2 2 0.0018 17 0 0 0 5.81E+06 2.22E+06 - - - 6.508 1 221125_WJC_METTL3_EV_vs_WT_F10.10753.10753.3 7.05E-11 15/60 R.EYEDNDEVHIEVHNPR[166.11].N "sp|Q9UKF6|CPSF3_HUMAN,tr|G5E9W3|G5E9W3_HUMAN" 2 2003.8849 1.18 142620 10753 3 2003.885841 668.9689 Cleavage and polyadenylation specificity factor subunit 3 OS=Homo sapiens OX=9606 GN=CPSF3 PE=1 SV=1 4.35 2202.8 - 257604 - - - 0.4861 - 2.764 0.706 - 301.8 1 2 0 0.001 16 0 0 0 5.84E+06 4.94E+06 - - - 9.0196 1 221125_WJC_METTL3_EV_vs_WT_F10.10754.10754.3 2.27E-10 14/72 K.KLEPLSQDEDQHADLTQSR.R "sp|P49366|DHYS_HUMAN,tr|M0QX43|M0QX43_HUMAN,tr|Q5J8M5|Q5J8M5_HUMAN,tr|B4E3M2|B4E3M2_HUMAN,tr|M0R264|M0R264_HUMAN,tr|A0A087WZK0|A0A087WZK0_HUMAN,tr|A0A3B3IU31|A0A3B3IU31_HUMAN,tr|M0R253|M0R253_HUMAN,tr|M0R0J4|M0R0J4_HUMAN,tr|M0QYZ7|M0QYZ7_HUMAN" 10 2209.0611 1.1 142621 10754 3 2209.063578 737.361 Deoxyhypusine synthase OS=Homo sapiens OX=9606 GN=DHPS PE=1 SV=1 4.43 2202.9 - 245069 - - - 1.1199 - 3.387 0.571 - 227.6 1 2 0 0.0025 19 0 0 0 3.39E+06 3.08E+06 - - - 7.9026 0.9994 221125_WJC_METTL3_EV_vs_WT_F10.10755.10755.2 0.00224 12-Jun K.DNNLLGR[166.11].F "sp|P0DMV8|HS71A_HUMAN,sp|P34931|HS71L_HUMAN,sp|P0DMV9|HS71B_HUMAN,sp|P17066|HSP76_HUMAN,tr|Q53FA3|Q53FA3_HUMAN,tr|V9GZ37|V9GZ37_HUMAN,tr|A0A0G2JIW1|A0A0G2JIW1_HUMAN" 7 810.4223 0.14 142622 10755 2 810.422751 406.2184 Heat shock 70 kDa protein 1A OS=Homo sapiens OX=9606 GN=HSPA1A PE=1 SV=1 5.84 2203 - 226508 - - - 0.5121 - 1.417 0.386 - 203.4 1 2 0 0.0004 7 0 0 0 5.71E+05 4.19E+06 - - - 2.9962 0.9995 221125_WJC_METTL3_EV_vs_WT_F10.10759.10759.4 9.62E-06 14/84 K.QPPKPPQIHYC[160.03]DVC[160.03]K.L sp|Q96KR1|ZFR_HUMAN 1 1865.8917 1.44 142624 10759 4 1865.901023 467.4802 Zinc finger RNA-binding protein OS=Homo sapiens OX=9606 GN=ZFR PE=1 SV=2 8.04 2203.6 - 502546 - - - 5.018 - 2.661 0.497 - 136.8 1 2 0 0.0094 15 0 0 0 1.93E+07 1.34E+07 - - - 3.8995 1 221125_WJC_METTL3_EV_vs_WT_F10.10761.10761.3 6.56E-12 16/92 K.LEAIEDDSVK[136.11]ETDSSSASAATPSK[136.11].K "sp|P54578|UBP14_HUMAN,tr|A6NJA2|A6NJA2_HUMAN" 2 2453.1628 1.01 142626 10761 3 2453.164234 818.7282 Ubiquitin carboxyl-terminal hydrolase 14 OS=Homo sapiens OX=9606 GN=USP14 PE=1 SV=3 4.02 2203.8 - 286787 - - - 0.5894 - 3.506 0.683 - 219.3 1 2 1 0.0014 24 0 0 0 3.98E+06 3.95E+06 - - - 9.068 0.9995 221125_WJC_METTL3_EV_vs_WT_F10.10762.10762.3 0.000462 Dec-64 K.NFSYK[136.11]DDDR[166.11]YEQASDVR[166.11].A "sp|O00268|TAF4_HUMAN,tr|A0A0G2JRY5|A0A0G2JRY5_HUMAN" 2 2134.955 2.63 142627 10762 3 2134.95521 712.6589 Transcription initiation factor TFIID subunit 4 OS=Homo sapiens OX=9606 GN=TAF4 PE=1 SV=2 4.36 2203.9 - 211711 - - - 0.0909 - 1.966 0.433 - 107.2 1 2 2 0.0002 17 0 0 0 5.73E+06 2.18E+06 - - - 5.0752 0.9911 221125_WJC_METTL3_EV_vs_WT_F10.10764.10764.4 1.38E-06 15/126 S.SVVLHDEGQNEEDVEKEEETER.M "sp|Q9Y2L1|RRP44_HUMAN,tr|F2Z2C0|F2Z2C0_HUMAN,tr|G3V1J5|G3V1J5_HUMAN" 3 2599.1522 1.36 142629 10764 4 2599.156082 650.7953 Exosome complex exonuclease RRP44 OS=Homo sapiens OX=9606 GN=DIS3 PE=1 SV=2 4.04 2204.2 - 99718 - - - 1.5078 - 2.536 0.592 - 127.7 1 1 1 0.0039 22 0 0 0 1.09E+07 8.06E+06 - - - 4.6822 0.9999 221125_WJC_METTL3_EV_vs_WT_F10.10768.10768.3 0.00147 Sep-36 R.K[136.11]QDSGHLDLR[166.11].N "sp|Q86U44|MTA70_HUMAN,tr|B4E349|B4E349_HUMAN,tr|F5H6D8|F5H6D8_HUMAN,tr|B4DTN4|B4DTN4_HUMAN" 4 1185.6221 0.08 142632 10768 3 1185.622513 396.2146 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 6.75 2204.7 - 280751 - - - 0.3441 - 2.006 0.433 - 110.2 1 2 0 0.0004 10 0 0 0 7.35E+05 9.50E+06 - - - 5.4004 1 221125_WJC_METTL3_EV_vs_WT_F10.10769.10769.3 8.89E-10 25/80 K.GPSHSGNPSHGTLGLSGTLGR[166.11].A sp|Q86XN7|PRSR1_HUMAN 1 1997.9907 1.86 142633 10769 3 1997.992095 667.0042 Proline and serine-rich protein 1 OS=Homo sapiens OX=9606 GN=PROSER1 PE=1 SV=2 9.76 2204.8 - 1.31E+06 - - - 0.7132 - 4.658 0.689 - 692.5 1 2 0 0.0014 21 0 0 0 4.17E+07 2.24E+07 - - - 9.91 1 221125_WJC_METTL3_EV_vs_WT_F10.10776.10776.3 2.88E-10 13/72 K.K[136.11]LEPLSQDEDQHADLTQSR[166.11].R "sp|P49366|DHYS_HUMAN,tr|M0QX43|M0QX43_HUMAN,tr|Q5J8M5|Q5J8M5_HUMAN,tr|B4E3M2|B4E3M2_HUMAN,tr|M0R264|M0R264_HUMAN,tr|A0A087WZK0|A0A087WZK0_HUMAN,tr|A0A3B3IU31|A0A3B3IU31_HUMAN,tr|M0R253|M0R253_HUMAN,tr|M0R0J4|M0R0J4_HUMAN,tr|M0QYZ7|M0QYZ7_HUMAN" 10 2227.0836 1.1 142638 10776 3 2227.085003 743.3685 Deoxyhypusine synthase OS=Homo sapiens OX=9606 GN=DHPS PE=1 SV=1 4.43 2205.7 - 222725 - - - 0.6416 - 2.446 0.625 - 197 1 2 0 0.0014 19 0 0 0 3.39E+06 3.08E+06 - - - 7.7052 1 221125_WJC_METTL3_EV_vs_WT_F10.10777.10777.4 6.45E-10 18/108 K.KLEPLSQDEDQHADLTQSR.R "sp|P49366|DHYS_HUMAN,tr|M0QX43|M0QX43_HUMAN,tr|Q5J8M5|Q5J8M5_HUMAN,tr|B4E3M2|B4E3M2_HUMAN,tr|M0R264|M0R264_HUMAN,tr|A0A087WZK0|A0A087WZK0_HUMAN,tr|A0A3B3IU31|A0A3B3IU31_HUMAN,tr|M0R253|M0R253_HUMAN,tr|M0R0J4|M0R0J4_HUMAN,tr|M0QYZ7|M0QYZ7_HUMAN" 10 2209.0611 0.81 142639 10777 4 2209.067331 553.2726 Deoxyhypusine synthase OS=Homo sapiens OX=9606 GN=DHPS PE=1 SV=1 4.43 2205.8 - 343361 - - - 2.8188 - 3.398 0.608 - 367.2 1 2 0 0.0062 19 0 0 0 6.40E+06 7.90E+06 - - - 4.9301 1 221125_WJC_METTL3_EV_vs_WT_F10.10778.10778.3 2.31E-13 20/84 R.RQDSDLVQC[160.03]GVTSPSSAEATGK.L sp|Q9HC52|CBX8_HUMAN 1 2292.0652 999 142640 10778 3 2292.060039 765.029 Chromobox protein homolog 8 OS=Homo sapiens OX=9606 GN=CBX8 PE=1 SV=3 4.56 2206 - 277688 - - - -2.253 - 4.051 0.74 - 471.7 1 2 0 -0.0052 22 0 0 0 1.11E+07 0.00E+00 - - - 10.1055 0.9999 221125_WJC_METTL3_EV_vs_WT_F10.10784.10784.2 4.55E-06 Jul-42 K.EAQSSQATPVQTSQPDSSNIVK[136.11].V "sp|Q8IZH2|XRN1_HUMAN,tr|H7C5E4|H7C5E4_HUMAN" 2 2309.1226 1.56 142643 10784 2 2309.122782 1155.5686 5'-3' exoribonuclease 1 OS=Homo sapiens OX=9606 GN=XRN1 PE=1 SV=1 4.37 2206.7 - 122615 - - - 0.058 - 1.742 0.635 - 70.2 1 2 0 0.0001 22 0 0 0 4.32E+06 2.76E+06 - - - 5.0956 0.9989 221125_WJC_METTL3_EV_vs_WT_F10.10785.10785.3 0.00832 Aug-56 K.QPPK[136.11]PPQIHYC[160.03]DVC[160.03]K[136.11].L sp|Q96KR1|ZFR_HUMAN 1 1881.9201 1.91 142644 10785 3 1881.923871 628.314 Zinc finger RNA-binding protein OS=Homo sapiens OX=9606 GN=ZFR PE=1 SV=2 8.04 2206.9 - 171460 - - - 2.0251 - 1.479 0.373 - 64.7 1 2 0 0.0038 15 0 0 0 9.15E+06 4.78E+06 - - - 3.7187 0.9887 221125_WJC_METTL3_EV_vs_WT_F10.10787.10787.3 1.11E-06 Oct-84 S.SVVLHDEGQNEEDVEK[136.11]EEETER[166.11].M "sp|Q9Y2L1|RRP44_HUMAN,tr|F2Z2C0|F2Z2C0_HUMAN,tr|G3V1J5|G3V1J5_HUMAN" 3 2617.1746 1.96 142646 10787 3 2617.178833 873.3988 Exosome complex exonuclease RRP44 OS=Homo sapiens OX=9606 GN=DIS3 PE=1 SV=2 4.04 2207.1 - 112912 - - - 1.6048 - 2.479 0.607 - 102.4 1 1 1 0.0042 22 0 0 0 3.53E+06 1.80E+06 - - - 7.4587 1 221125_WJC_METTL3_EV_vs_WT_F10.10791.10791.3 9.66E-07 16/84 S.SVVLHDEGQNEEDVEKEEETER.M "sp|Q9Y2L1|RRP44_HUMAN,tr|F2Z2C0|F2Z2C0_HUMAN,tr|G3V1J5|G3V1J5_HUMAN" 3 2599.1522 1.96 142648 10791 3 2599.151883 867.3913 Exosome complex exonuclease RRP44 OS=Homo sapiens OX=9606 GN=DIS3 PE=1 SV=2 4.04 2207.7 - 229531 - - - -0.1077 - 3.249 0.647 - 134 1 1 1 -0.0003 22 0 0 0 3.53E+06 1.80E+06 - - - 8.547 0.9999 221125_WJC_METTL3_EV_vs_WT_F10.10793.10793.3 4.16E-05 Sep-56 K.QPPKPPQIHYC[160.03]DVC[160.03]K.L sp|Q96KR1|ZFR_HUMAN 1 1865.8917 2.01 142650 10793 3 1865.893778 622.9712 Zinc finger RNA-binding protein OS=Homo sapiens OX=9606 GN=ZFR PE=1 SV=2 8.04 2207.9 - 207344 - - - 1.1351 - 2.064 0.458 - 94.4 1 2 0 0.0021 15 0 0 0 9.64E+06 4.80E+06 - - - 5.5365 0.9708 221125_WJC_METTL3_EV_vs_WT_F10.10798.10798.4 2.92E-05 18/132 R.PGRPADKDAASC[160.03]GPGAAVAAVER.G sp|A6NJT0|UNC4_HUMAN 1 2222.0862 3.38 142652 10798 4 2222.090978 556.5288 Homeobox protein unc-4 homolog OS=Homo sapiens OX=9606 GN=UNCX PE=3 SV=1 6.5 2208.6 - 229838 - - - 2.1444 - 3.448 0.489 - 208.7 1 1 1 0.0048 23 0 0 0 1.08E+07 3.20E+06 - - - 3.882 1 221125_WJC_METTL3_EV_vs_WT_F10.10801.10801.2 1.11E-10 Nov-42 K.EAQSSQATPVQTSQPDSSNIVK.V "sp|Q8IZH2|XRN1_HUMAN,tr|H7C5E4|H7C5E4_HUMAN" 2 2301.1084 1.56 142655 10801 2 2301.110345 1151.5615 5'-3' exoribonuclease 1 OS=Homo sapiens OX=9606 GN=XRN1 PE=1 SV=1 4.37 2209 - 182592 - - - 0.8244 - 2.553 0.642 - 192.9 1 2 0 0.0019 22 0 0 0 4.32E+06 2.76E+06 - - - 6.0865 0.9985 221125_WJC_METTL3_EV_vs_WT_F10.10809.10809.4 0.0219 8/126 K.ILEHMPVSNQKPDTDEAEDPEK.M sp|Q9BUQ8|DDX23_HUMAN 1 2521.1642 3.57 142661 10809 4 2521.167539 631.2983 Probable ATP-dependent RNA helicase DDX23 OS=Homo sapiens OX=9606 GN=DDX23 PE=1 SV=3 4.19 2210 - 228782 - - - 1.3053 - 1.502 0.292 - 35 1 2 0 0.0033 22 0 0 0 8.32E+06 2.33E+06 - - - 1.8998 0.8774 221125_WJC_METTL3_EV_vs_WT_F10.10810.10810.4 0.32 Jun-78 K.VEYSEEELKTHISK.G "sp|P12956|XRCC6_HUMAN,tr|B1AHC9|B1AHC9_HUMAN" 2 1690.8414 1.01 142662 10810 4 1690.84111 423.7176 X-ray repair cross-complementing protein 6 OS=Homo sapiens OX=9606 GN=XRCC6 PE=1 SV=2 4.91 2210.1 - 230811 - - - -0.1603 - 0.954 0.177 - 18.4 1 2 1 -0.0003 14 0 0 0 2.97E+06 2.95E+06 - - - 0.7494 0.9999 221125_WJC_METTL3_EV_vs_WT_F10.10816.10816.3 2.92E-05 Dec-60 K.NK[136.11]EDQYDHLDAADMTK[136.11].V sp|P34932|HSP74_HUMAN 1 1908.8495 0.08 142665 10816 3 1908.850115 637.2904 Heat shock 70 kDa protein 4 OS=Homo sapiens OX=9606 GN=HSPA4 PE=1 SV=4 4.35 2210.9 - 351702 - - - 0.3452 - 2.889 0.543 - 117.2 1 2 1 0.0007 16 0 0 0 1.10E+07 1.45E+08 - - - 7.3159 1 221125_WJC_METTL3_EV_vs_WT_F10.10831.10831.3 5.54E-11 23/76 R.SSLGQSASETEEDTVSVSK[136.11]K[136.11].E "sp|Q13435|SF3B2_HUMAN,tr|E9PPJ0|E9PPJ0_HUMAN,tr|H0YCG1|H0YCG1_HUMAN,tr|E9PJ04|E9PJ04_HUMAN" 4 2084.0092 1 142677 10831 3 2084.009164 695.677 Splicing factor 3B subunit 2 OS=Homo sapiens OX=9606 GN=SF3B2 PE=1 SV=2 4.41 2212.7 - 270312 - - - -0.0115 - 4.05 0.632 - 312.4 1 2 0 0 20 0 0 0 2.32E+07 2.32E+07 - - - 8.9795 0.9999 221125_WJC_METTL3_EV_vs_WT_F10.10832.10832.3 2.46E-07 Oct-80 R.VPSGGYSSINNVQDPQKPEPR.D "sp|Q9UKM7|MA1B1_HUMAN,tr|A0A804HL61|A0A804HL61_HUMAN,tr|A0A804HJ66|A0A804HJ66_HUMAN,tr|H0YI64|H0YI64_HUMAN" 4 2268.1135 2.3 142678 10832 3 2268.122115 757.0451 "Endoplasmic reticulum mannosyl-oligosaccharide 1,2-alpha-mannosidase OS=Homo sapiens OX=9606 GN=MAN1B1 PE=1 SV=2" 6.04 2212.9 - 143707 - - - 3.8098 - 2.375 0.582 - 76.2 1 2 0 0.0086 21 0 0 0 3.34E+06 1.45E+06 - - - 7.1001 0.9999 221125_WJC_METTL3_EV_vs_WT_F10.10846.10846.4 8.56E-08 16/90 K.NK[136.11]EDQYDHLDAADMTK[136.11].V sp|P34932|HSP74_HUMAN 1 1908.8495 0.07 142688 10846 4 1908.853598 478.2196 Heat shock 70 kDa protein 4 OS=Homo sapiens OX=9606 GN=HSPA4 PE=1 SV=4 4.35 2214.8 - 4.23E+06 - - - 2.1699 - 3.285 0.616 - 219.5 1 2 1 0.0041 16 0 0 0 1.09E+07 1.53E+08 - - - 5.0055 0.9919 221125_WJC_METTL3_EV_vs_WT_F10.10847.10847.3 0.000727 Sep-44 R.KKEEQVIQVWNK.K "sp|Q9Y520|PRC2C_HUMAN,tr|E7EPN9|E7EPN9_HUMAN,tr|H7C5N8|H7C5N8_HUMAN" 3 1527.8409 1.83 142689 10847 3 1527.844535 510.2876 Protein PRRC2C OS=Homo sapiens OX=9606 GN=PRRC2C PE=1 SV=4 8.5 2214.9 - 222058 - - - 2.3608 - 1.778 0.306 - 122.9 1 2 1 0.0036 12 0 0 0 6.88E+06 3.75E+06 - - - 3.5458 0.9847 221125_WJC_METTL3_EV_vs_WT_F10.10849.10849.3 3.51E-05 13/52 K.R[166.11]PK[136.11]EEEWDPEYTPK[136.11].S "sp|Q9NYF8|BCLF1_HUMAN,tr|H0YF14|H0YF14_HUMAN" 2 1828.8842 2.47 142691 10849 3 1828.894633 610.6353 Bcl-2-associated transcription factor 1 OS=Homo sapiens OX=9606 GN=BCLAF1 PE=1 SV=2 4.59 2215.1 - 178837 - - - 5.7051 - 2.253 0.384 - 268.6 1 2 1 0.0104 14 0 0 0 4.39E+08 1.77E+08 - - - 4.9769 0.9999 221125_WJC_METTL3_EV_vs_WT_F10.10854.10854.3 3.29E-06 22/52 K.RPKEEEWDPEYTPK.S "sp|Q9NYF8|BCLF1_HUMAN,tr|H0YF14|H0YF14_HUMAN" 2 1802.8475 2.48 142694 10854 3 1802.851805 601.9565 Bcl-2-associated transcription factor 1 OS=Homo sapiens OX=9606 GN=BCLAF1 PE=1 SV=2 4.59 2215.8 - 786797 - - - 2.3718 - 3.648 0.528 - 971.5 1 2 1 0.0043 14 0 0 0 4.40E+08 1.77E+08 - - - 7.8648 0.9979 221125_WJC_METTL3_EV_vs_WT_F10.10857.10857.2 7.77E-07 30-Jul K.NK[136.11]EDQYDHLDAADMTK[136.11].V sp|P34932|HSP74_HUMAN 1 1908.8495 0.001 142697 10857 2 1908.852813 955.432 Heat shock 70 kDa protein 4 OS=Homo sapiens OX=9606 GN=HSPA4 PE=1 SV=4 4.35 2216.2 - 82232.1 - - - 1.7587 - 1.843 0.645 - 109.2 1 2 1 0.0034 16 0 0 0 0.00E+00 1.14E+06 - - - 5.3071 0.9998 221125_WJC_METTL3_EV_vs_WT_F10.10861.10861.4 1.08E-07 14/132 R.NTAQASPAGAKPGIADSVMEPHK.K "sp|Q8IXK0|PHC2_HUMAN,tr|A0A0A0MSI2|A0A0A0MSI2_HUMAN" 2 2276.1219 1.8 142699 10861 4 2276.130813 570.0378 Polyhomeotic-like protein 2 OS=Homo sapiens OX=9606 GN=PHC2 PE=1 SV=1 6.75 2216.8 - 209146 - - - 3.9027 - 3.029 0.504 - 125.3 1 2 0 0.0089 23 0 0 0 5.86E+06 3.26E+06 - - - 3.9694 0.9998 221125_WJC_METTL3_EV_vs_WT_F10.10863.10863.4 9.52E-07 14/90 K.NKEDQYDHLDAADMTK.V sp|P34932|HSP74_HUMAN 1 1892.8211 0.07 142701 10863 4 1892.82602 474.2125 Heat shock 70 kDa protein 4 OS=Homo sapiens OX=9606 GN=HSPA4 PE=1 SV=4 4.35 2217 - 519655 - - - 2.6225 - 2.788 0.565 - 196.5 1 2 1 0.005 16 0 0 0 1.09E+07 1.53E+08 - - - 4.5036 0.8948 221125_WJC_METTL3_EV_vs_WT_F10.10864.10864.3 0.0381 Oct-44 R.K[136.11]K[136.11]EEQVIQVWNK[136.11].K "sp|Q9Y520|PRC2C_HUMAN,tr|E7EPN9|E7EPN9_HUMAN,tr|H7C5N8|H7C5N8_HUMAN" 3 1551.8835 1.65 142702 10864 3 1551.88476 518.3018 Protein PRRC2C OS=Homo sapiens OX=9606 GN=PRRC2C PE=1 SV=4 8.5 2217.1 - 219303 - - - 0.7939 - 1.447 0.153 - 93 1 2 1 0.0012 12 0 0 0 6.20E+06 3.75E+06 - - - 1.2696 0.9963 221125_WJC_METTL3_EV_vs_WT_F10.10865.10865.4 0.0395 Sep-72 R.HLYTK[136.11]DIDIHEVR[166.11].L "sp|Q00839|HNRPU_HUMAN,tr|A0A1W2PQL0|A0A1W2PQL0_HUMAN,tr|A0A1W2PPL4|A0A1W2PPL4_HUMAN,tr|A0A1W2PQ74|A0A1W2PQ74_HUMAN,tr|Q5RI18|Q5RI18_HUMAN,tr|A0A1W2PP35|A0A1W2PP35_HUMAN,tr|A0A1W2PPS1|A0A1W2PPS1_HUMAN,tr|A0A1W2PRZ7|A0A1W2PRZ7_HUMAN,tr|A0A1W2PPH7|A0A1W2PPH7_HUMAN,tr|A0A1W2PP34|A0A1W2PP34_HUMAN,tr|A0A1X7SBS1|A0A1X7SBS1_HUMAN" 11 1655.875 0.99 142703 10865 4 1655.87466 414.976 Heterogeneous nuclear ribonucleoprotein U OS=Homo sapiens OX=9606 GN=HNRNPU PE=1 SV=6 6 2217.3 - 99592.8 - - - -0.2204 - 1.621 0.308 - 65.5 1 2 1 -0.0004 13 0 0 0 4.60E+06 4.63E+06 - - - 2.0858 1 221125_WJC_METTL3_EV_vs_WT_F10.10868.10868.3 1.05E-11 26/76 R.SSLGQSASETEEDTVSVSKK.E "sp|Q13435|SF3B2_HUMAN,tr|E9PPJ0|E9PPJ0_HUMAN,tr|H0YCG1|H0YCG1_HUMAN,tr|E9PJ04|E9PJ04_HUMAN" 4 2067.9808 1 142704 10868 3 2067.983803 690.3342 Splicing factor 3B subunit 2 OS=Homo sapiens OX=9606 GN=SF3B2 PE=1 SV=2 4.41 2217.7 - 1.61E+06 - - - 1.4579 - 4.74 0.671 - 1163.5 1 2 0 0.003 20 0 0 0 2.32E+07 2.32E+07 - - - 9.7951 0.9999 221125_WJC_METTL3_EV_vs_WT_F10.10869.10869.3 2.16E-08 17/60 K.NKEDQYDHLDAADMTK.V sp|P34932|HSP74_HUMAN 1 1892.8211 0.08 142705 10869 3 1892.82517 631.9476 Heat shock 70 kDa protein 4 OS=Homo sapiens OX=9606 GN=HSPA4 PE=1 SV=4 4.35 2217.8 - 616950 - - - 2.1735 - 3.293 0.549 - 373.8 1 2 1 0.0041 16 0 0 0 1.11E+07 1.45E+08 - - - 7.7177 0.9997 221125_WJC_METTL3_EV_vs_WT_F10.10872.10872.3 0.0403 Dec-48 K.HR[166.11]DYETATLSDIK[136.11].A "sp|O43707|ACTN4_HUMAN,tr|F5GXS2|F5GXS2_HUMAN,tr|H7C144|H7C144_HUMAN" 3 1565.7805 1.36 142708 10872 3 1565.783083 522.9341 Alpha-actinin-4 OS=Homo sapiens OX=9606 GN=ACTN4 PE=1 SV=2 5.38 2218.2 - 203387 - - - 1.6778 - 2.654 0.436 - 206.6 1 2 1 0.0026 13 0 0 0 7.44E+06 5.45E+06 - - - 6.0466 0.9998 221125_WJC_METTL3_EV_vs_WT_F10.10876.10876.4 3.49E-05 18/78 K.R[166.11]PK[136.11]EEEWDPEYTPK[136.11].S "sp|Q9NYF8|BCLF1_HUMAN,tr|H0YF14|H0YF14_HUMAN" 2 1828.8842 2.36 142710 10876 4 1828.886672 458.2283 Bcl-2-associated transcription factor 1 OS=Homo sapiens OX=9606 GN=BCLAF1 PE=1 SV=2 4.59 2218.7 - 578624 - - - 1.3522 - 2.765 0.475 - 233.8 1 2 1 0.0025 14 0 0 0 1.47E+08 6.21E+07 - - - 3.7299 1 221125_WJC_METTL3_EV_vs_WT_F10.10879.10879.4 4.28E-05 14/96 K.SEDYPHETMAPDIHEER.Q "sp|Q03112|MECOM_HUMAN,tr|E7ERX0|E7ERX0_HUMAN,tr|E7EUL6|E7EUL6_HUMAN,tr|A0A0C3SFZ7|A0A0C3SFZ7_HUMAN,tr|A0A1B0GXI8|A0A1B0GXI8_HUMAN,tr|E9PGE9|E9PGE9_HUMAN,tr|E7EPY2|E7EPY2_HUMAN,tr|E7EU48|E7EU48_HUMAN" 8 2054.864 1.7 142713 10879 4 2054.865566 514.7233 Histone-lysine N-methyltransferase MECOM OS=Homo sapiens OX=9606 GN=MECOM PE=1 SV=3 4.35 2219.1 - 246248 - - - 0.7699 - 2.829 0.575 - 230.7 1 2 0 0.0016 17 0 0 0 4.21E+06 2.48E+06 - - - 4.5914 1 221125_WJC_METTL3_EV_vs_WT_F10.10892.10892.3 1.05E-07 16/52 K.RNREEEWDPEYTPK.S "sp|Q9Y2W1|TR150_HUMAN,tr|A0A3B3ITZ9|A0A3B3ITZ9_HUMAN" 2 1847.8438 2.33 142722 10892 3 1847.844629 616.9552 Thyroid hormone receptor-associated protein 3 OS=Homo sapiens OX=9606 GN=THRAP3 PE=1 SV=2 4.59 2220.8 - 284845 - - - 0.4264 - 2.907 0.612 - 263.2 1 2 1 0.0008 14 0 0 0 1.44E+08 6.17E+07 - - - 8.1989 0.9995 221125_WJC_METTL3_EV_vs_WT_F10.10893.10893.3 0.000181 Nov-60 R.TREEGKDWAEAVGASR.V sp|Q5JSZ5|PRC2B_HUMAN 1 1760.8442 1.82 142723 10893 3 1760.845477 587.9553 Protein PRRC2B OS=Homo sapiens OX=9606 GN=PRRC2B PE=1 SV=2 4.87 2221 - 255955 - - - 0.7394 - 2.025 0.434 - 163.5 1 2 2 0.0013 16 0 0 0 2.49E+07 1.37E+07 - - - 5.1887 0.9995 221125_WJC_METTL3_EV_vs_WT_F10.10894.10894.4 4.06E-05 15/90 R.TREEGKDWAEAVGASR.V sp|Q5JSZ5|PRC2B_HUMAN 1 1760.8442 1.37 142724 10894 4 1760.848221 441.2183 Protein PRRC2B OS=Homo sapiens OX=9606 GN=PRRC2B PE=1 SV=2 4.87 2221.1 - 258058 - - - 2.2978 - 2.696 0.452 - 129.1 1 2 2 0.004 16 0 0 0 1.92E+07 1.40E+07 - - - 3.5084 0.9995 221125_WJC_METTL3_EV_vs_WT_F10.10901.10901.3 1.26E-05 16/48 K.HRDYETATLSDIK.A "sp|O43707|ACTN4_HUMAN,tr|F5GXS2|F5GXS2_HUMAN,tr|H7C144|H7C144_HUMAN" 3 1547.758 1.37 142729 10901 3 1547.758466 516.9266 Alpha-actinin-4 OS=Homo sapiens OX=9606 GN=ACTN4 PE=1 SV=2 5.38 2222 - 345823 - - - 0.3101 - 2.911 0.329 - 297.8 1 2 1 0.0005 13 0 0 0 7.47E+06 5.45E+06 - - - 5.1049 0.9997 221125_WJC_METTL3_EV_vs_WT_F10.10902.10902.4 1.43E-06 20/78 K.RPKEEEWDPEYTPK.S "sp|Q9NYF8|BCLF1_HUMAN,tr|H0YF14|H0YF14_HUMAN" 2 1802.8475 2.37 142730 10902 4 1802.851645 451.7192 Bcl-2-associated transcription factor 1 OS=Homo sapiens OX=9606 GN=BCLAF1 PE=1 SV=2 4.59 2222.1 - 3.18E+06 - - - 2.2831 - 3.262 0.482 - 408.8 1 2 1 0.0041 14 0 0 0 1.47E+08 6.21E+07 - - - 3.8505 0.9984 221125_WJC_METTL3_EV_vs_WT_F10.10904.10904.3 0.000139 14/60 R.TR[166.11]EEGK[136.11]DWAEAVGASR[166.11].V sp|Q5JSZ5|PRC2B_HUMAN 1 1788.8749 1.8 142732 10904 3 1788.882256 597.2989 Protein PRRC2B OS=Homo sapiens OX=9606 GN=PRRC2B PE=1 SV=2 4.87 2222.3 - 302117 - - - 4.1037 - 2.647 0.46 - 316.1 1 2 2 0.0073 16 0 0 0 2.34E+07 1.30E+07 - - - 6.1642 0.9946 221125_WJC_METTL3_EV_vs_WT_F10.10908.10908.2 0.00346 26-Jun K.RPKEEEWDPEYTPK.S "sp|Q9NYF8|BCLF1_HUMAN,tr|H0YF14|H0YF14_HUMAN" 2 1802.8475 5.42 142736 10908 2 1802.848279 902.431 Bcl-2-associated transcription factor 1 OS=Homo sapiens OX=9606 GN=BCLAF1 PE=1 SV=2 4.59 2222.9 - 58815.6 - - - 0.416 - 1.611 0.39 - 99.2 1 2 1 0.0008 14 0 0 0 4.74E+06 8.75E+05 - - - 3.1179 0.999 221125_WJC_METTL3_EV_vs_WT_F10.10915.10915.4 0.00478 10/114 K.SAK[136.11]PTK[136.11]PAASDLPVPAEGVR[166.11].N "sp|Q05682|CALD1_HUMAN,tr|C9J813|C9J813_HUMAN,tr|E7EX44|E7EX44_HUMAN,tr|A0A6Q8PGI1|A0A6Q8PGI1_HUMAN,tr|E9PGZ1|E9PGZ1_HUMAN" 5 2016.1214 0.43 142741 10915 4 2016.117758 505.0376 Caldesmon OS=Homo sapiens OX=9606 GN=CALD1 PE=1 SV=3 8.31 2223.8 - 127710 - - - -1.8114 - 1.888 0.312 - 45.2 1 2 0 -0.0037 20 0 0 0 4.56E+06 1.05E+07 - - - 2.1531 0.9999 221125_WJC_METTL3_EV_vs_WT_F10.10929.10929.4 1.59E-07 20/114 R.LLEGEDAHLTQYKKEPVTTR.Q "sp|Q04695|K1C17_HUMAN,tr|F5GWP8|F5GWP8_HUMAN" 2 2327.2121 999 142752 10929 4 2327.217099 582.8103 "Keratin, type I cytoskeletal 17 OS=Homo sapiens OX=9606 GN=KRT17 PE=1 SV=2" 5.53 2225.5 - 357807 - - - 2.1373 - 3.485 0.597 - 239.1 1 2 1 0.005 20 0 0 0 1.04E+07 0.00E+00 - - - 4.8383 0.9911 221125_WJC_METTL3_EV_vs_WT_F10.10933.10933.4 0.0104 9/114 K.SAKPTKPAASDLPVPAEGVR.N "sp|Q05682|CALD1_HUMAN,tr|C9J813|C9J813_HUMAN,tr|E7EX44|E7EX44_HUMAN,tr|A0A6Q8PGI1|A0A6Q8PGI1_HUMAN,tr|E9PGZ1|E9PGZ1_HUMAN" 5 1990.0847 0.43 142756 10933 4 1990.087857 498.5285 Caldesmon OS=Homo sapiens OX=9606 GN=CALD1 PE=1 SV=3 8.31 2226 - 97313.3 - - - 1.5663 - 1.863 0.212 - 54.3 1 2 0 0.0031 20 0 0 0 4.56E+06 1.05E+07 - - - 1.2784 1 221125_WJC_METTL3_EV_vs_WT_F10.10939.10939.3 4.39E-06 14/68 K.QAKPQHFQSDPEVASLPR.R "sp|Q9NSC2|SALL1_HUMAN,tr|H3BQ32|H3BQ32_HUMAN" 2 2034.0283 2.3 142761 10939 3 2034.029598 679.0167 Sal-like protein 1 OS=Homo sapiens OX=9606 GN=SALL1 PE=1 SV=2 6.75 2226.8 - 158584 - - - 0.644 - 2.836 0.531 - 220.4 1 2 0 0.0013 18 0 0 0 6.53E+06 2.84E+06 - - - 7.0554 0.9998 221125_WJC_METTL3_EV_vs_WT_F10.10955.10955.3 2.06E-06 15/52 K.R[166.11]NR[166.11]EEEWDPEYTPK[136.11].S "sp|Q9Y2W1|TR150_HUMAN,tr|A0A3B3ITZ9|A0A3B3ITZ9_HUMAN" 2 1875.8746 2.52 142773 10955 3 1875.877066 626.2988 Thyroid hormone receptor-associated protein 3 OS=Homo sapiens OX=9606 GN=THRAP3 PE=1 SV=2 4.59 2228.9 - 1.14E+06 - - - 1.3247 - 2.705 0.481 - 239.5 1 2 1 0.0025 14 0 0 0 1.58E+08 6.27E+07 - - - 6.5465 0.9999 221125_WJC_METTL3_EV_vs_WT_F10.10962.10962.4 9.96E-07 16/78 K.RNREEEWDPEYTPK.S "sp|Q9Y2W1|TR150_HUMAN,tr|A0A3B3ITZ9|A0A3B3ITZ9_HUMAN" 2 1847.8438 0.99 142778 10962 4 1847.844915 462.9682 Thyroid hormone receptor-associated protein 3 OS=Homo sapiens OX=9606 GN=THRAP3 PE=1 SV=2 4.59 2229.9 - 3.11E+06 - - - 0.5812 - 2.441 0.548 - 201.6 1 2 1 0.0011 14 0 0 0 9.07E+07 9.20E+07 - - - 4.3203 0.9999 221125_WJC_METTL3_EV_vs_WT_F10.10972.10972.4 7.58E-08 26/114 K.AGDRDPLGNDC[160.03]PEQDRLPQR.S sp|Q9Y5Z9|UBIA1_HUMAN 1 2308.0615 1.23 142786 10972 4 2308.061805 578.0226 UbiA prenyltransferase domain-containing protein 1 OS=Homo sapiens OX=9606 GN=UBIAD1 PE=1 SV=1 4.36 2231 - 573565 - - - 0.1516 - 3.818 0.591 - 467.7 1 2 2 0.0003 20 0 0 0 1.53E+07 1.25E+07 - - - 4.8179 0.9996 221125_WJC_METTL3_EV_vs_WT_F10.10978.10978.4 2.21E-06 16/126 R.ALDVTDK[136.11]EGEER[166.11]EDADVSVTQR[166.11].T "sp|Q9NVI1|FANCI_HUMAN,tr|F8W7R3|F8W7R3_HUMAN,tr|A0A6Q8PGF4|A0A6Q8PGF4_HUMAN,tr|A0A6Q8PH09|A0A6Q8PH09_HUMAN,tr|H3BP78|H3BP78_HUMAN" 5 2489.1876 1.84 142790 10978 4 2489.18652 623.3042 Fanconi anemia group I protein OS=Homo sapiens OX=9606 GN=FANCI PE=1 SV=4 4.07 2231.8 - 324038 - - - -0.4319 - 2.484 0.425 - 177.7 1 2 2 -0.0011 22 0 0 0 9.02E+06 4.91E+06 - - - 3.2226 0.9999 221125_WJC_METTL3_EV_vs_WT_F10.10980.10980.3 0.000309 Oct-44 K.LHGVNINVEASK.N "sp|Q9BWF3|RBM4_HUMAN,sp|Q9BQ04|RBM4B_HUMAN,tr|E9PM61|E9PM61_HUMAN,tr|D6R9K7|D6R9K7_HUMAN,tr|J3QRR5|J3QRR5_HUMAN,tr|E9PB51|E9PB51_HUMAN,tr|U3KQD5|U3KQD5_HUMAN,tr|E9PLB0|E9PLB0_HUMAN" 8 1279.6885 1.43 142792 10980 3 1279.688859 427.5701 RNA-binding protein 4 OS=Homo sapiens OX=9606 GN=RBM4 PE=1 SV=1 6.75 2232 - 171305 - - - 0.3196 - 2.159 0.407 - 161.5 1 2 0 0.0004 12 0 0 0 2.65E+06 1.85E+06 - - - 5.2109 0.9996 221125_WJC_METTL3_EV_vs_WT_F10.10997.10997.4 0.00263 10/132 K.LLK[136.11]EGEEPTVYSDEEEPK[136.11]DESAR[166.11].K sp|O00264|PGRC1_HUMAN 1 2675.266 1.65 142805 10997 4 2675.264045 669.8238 Membrane-associated progesterone receptor component 1 OS=Homo sapiens OX=9606 GN=PGRMC1 PE=1 SV=3 4.1 2234.3 - 179813 - - - -0.7386 - 1.819 0.439 - 40.4 1 2 2 -0.002 23 0 0 0 3.02E+06 1.83E+06 - - - 3.2403 0.9996 221125_WJC_METTL3_EV_vs_WT_F10.11001.11001.4 3.99E-06 13/108 R.SGDPRPQAAEPPDHLTITR.R "sp|Q96L14|C170L_HUMAN,sp|Q5SW79|CE170_HUMAN,tr|H0Y2V6|H0Y2V6_HUMAN,tr|E7EMW0|E7EMW0_HUMAN,tr|H0Y4T4|H0Y4T4_HUMAN,tr|E7EWM2|E7EWM2_HUMAN,tr|E5RG47|E5RG47_HUMAN" 7 2057.029 1.47 142807 11001 4 2057.037984 515.2645 Cep170-like protein OS=Homo sapiens OX=9606 GN=CEP170P1 PE=5 SV=2 5.36 2234.8 - 378383 - - - 4.3597 - 2.718 0.484 - 115.9 1 2 0 0.009 19 0 0 0 6.31E+07 4.28E+07 - - - 3.7745 0.9999 221125_WJC_METTL3_EV_vs_WT_F10.11002.11002.4 1.53E-07 14/132 K.LLKEGEEPTVYSDEEEPKDESAR.K sp|O00264|PGRC1_HUMAN 1 2649.2294 1.65 142808 11002 4 2649.230482 663.3146 Membrane-associated progesterone receptor component 1 OS=Homo sapiens OX=9606 GN=PGRMC1 PE=1 SV=3 4.1 2234.9 - 294828 - - - 0.4269 - 2.635 0.614 - 110.1 1 2 2 0.0011 23 0 0 0 3.02E+06 1.83E+06 - - - 4.8838 1 221125_WJC_METTL3_EV_vs_WT_F10.11003.11003.3 2.97E-08 14/60 K.AGDK[136.11]PHMQTYEVDLNK[136.11].C "sp|P21912|SDHB_HUMAN,tr|A0A087WWT1|A0A087WWT1_HUMAN" 2 1860.9011 0.37 142809 11003 3 1860.903276 621.3076 "Succinate dehydrogenase [ubiquinone] iron-sulfur subunit, mitochondrial OS=Homo sapiens OX=9606 GN=SDHB PE=1 SV=3" 5.38 2235.1 - 489295 - - - 1.1704 - 2.88 0.604 - 208.2 1 2 0 0.0022 16 0 0 0 2.92E+06 7.81E+06 - - - 7.9875 0.9993 221125_WJC_METTL3_EV_vs_WT_F10.11009.11009.3 0.00442 Aug-32 K.KDDSHWWSR.F sp|Q9Y4W6|AFG32_HUMAN 1 1215.5421 0.27 142815 11009 3 1215.544732 406.188 AFG3-like protein 2 OS=Homo sapiens OX=9606 GN=AFG3L2 PE=1 SV=2 6.75 2235.8 - 71300.8 - - - 2.1488 - 1.475 0.394 - 104.6 1 2 0 0.0026 9 0 0 0 9.13E+05 3.39E+06 - - - 4.1033 0.9952 221125_WJC_METTL3_EV_vs_WT_F10.11011.11011.3 0.207 Aug-36 R.K[136.11]QDSGHLDLR[166.11].N "sp|Q86U44|MTA70_HUMAN,tr|B4E349|B4E349_HUMAN,tr|F5H6D8|F5H6D8_HUMAN,tr|B4DTN4|B4DTN4_HUMAN" 4 1185.6221 0.19 142816 11011 3 1185.623656 396.2146 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 6.75 2236.2 - 237216 - - - 1.3082 - 1.403 0.26 - 107.5 1 2 0 0.0016 10 0 0 0 1.57E+06 8.42E+06 - - - 2.4272 0.9999 221125_WJC_METTL3_EV_vs_WT_F10.11013.11013.3 1.48E-05 Nov-64 R.QKNGDTSTEEPMLNVQR.L "sp|P82930|RT34_HUMAN,tr|C9JJ19|C9JJ19_HUMAN" 2 1945.9164 0.77 142817 11013 3 1945.915063 649.6461 "28S ribosomal protein S34, mitochondrial OS=Homo sapiens OX=9606 GN=MRPS34 PE=1 SV=2" 4.68 2236.4 - 760758 - - - -0.6634 - 2.618 0.49 - 139.1 1 2 1 -0.0013 17 0 0 0 1.01E+07 1.30E+07 - - - 6.434 1 221125_WJC_METTL3_EV_vs_WT_F10.11014.11014.4 3.85E-07 16/108 R.SGDPR[166.11]PQAAEPPDHLTITR[166.11].R "sp|Q96L14|C170L_HUMAN,sp|Q5SW79|CE170_HUMAN,tr|H0Y2V6|H0Y2V6_HUMAN,tr|E7EMW0|E7EMW0_HUMAN,tr|H0Y4T4|H0Y4T4_HUMAN,tr|E7EWM2|E7EWM2_HUMAN,tr|E5RG47|E5RG47_HUMAN" 7 2077.0456 1.49 142818 11014 4 2077.046519 520.2687 Cep170-like protein OS=Homo sapiens OX=9606 GN=CEP170P1 PE=5 SV=2 5.36 2236.5 - 1.01E+06 - - - 0.4636 - 2.857 0.534 - 212.3 1 2 0 0.001 19 0 0 0 6.43E+07 4.32E+07 - - - 4.2288 0.9997 221125_WJC_METTL3_EV_vs_WT_F10.11015.11015.4 0.000204 14/120 K.TVETRDGQVINETSQHHDDLE.- sp|P08670|VIME_HUMAN 1 2422.0997 1.78 142819 11015 4 2422.101243 606.5322 Vimentin OS=Homo sapiens OX=9606 GN=VIM PE=1 SV=4 4.44 2236.6 - 1.47E+06 - - - 0.6478 - 2.414 0.45 - 51.1 1 2 1 0.0016 21 0 0 0 1.54E+07 8.65E+06 - - - 3.4338 0.9996 221125_WJC_METTL3_EV_vs_WT_F10.11016.11016.3 0.00692 Oct-64 R.QK[136.11]NGDTSTEEPMLNVQR[166.11].L "sp|P82930|RT34_HUMAN,tr|C9JJ19|C9JJ19_HUMAN" 2 1963.9388 0.68 142820 11016 3 1963.936877 655.6536 "28S ribosomal protein S34, mitochondrial OS=Homo sapiens OX=9606 GN=MRPS34 PE=1 SV=2" 4.68 2236.7 - 539590 - - - -0.9914 - 2.181 0.422 - 114.8 1 2 1 -0.0019 17 0 0 0 9.92E+06 1.47E+07 - - - 5.2143 1 221125_WJC_METTL3_EV_vs_WT_F10.11019.11019.3 3.56E-05 13/72 R.SGDPRPQAAEPPDHLTITR.R "sp|Q96L14|C170L_HUMAN,sp|Q5SW79|CE170_HUMAN,tr|H0Y2V6|H0Y2V6_HUMAN,tr|E7EMW0|E7EMW0_HUMAN,tr|H0Y4T4|H0Y4T4_HUMAN,tr|E7EWM2|E7EWM2_HUMAN,tr|E5RG47|E5RG47_HUMAN" 7 2057.029 1.54 142823 11019 3 2057.029786 686.6836 Cep170-like protein OS=Homo sapiens OX=9606 GN=CEP170P1 PE=5 SV=2 5.36 2237.1 - 262218 - - - 0.3743 - 2.402 0.508 - 131.6 1 2 0 0.0008 19 0 0 0 1.47E+07 9.52E+06 - - - 6.3564 0.9732 221125_WJC_METTL3_EV_vs_WT_F10.11027.11027.4 0.00716 12/120 K.TVETR[166.11]DGQVINETSQHHDDLE.- sp|P08670|VIME_HUMAN 1 2432.1079 1.78 142829 11027 4 2432.100021 609.0343 Vimentin OS=Homo sapiens OX=9606 GN=VIM PE=1 SV=4 4.44 2238.1 - 1.16E+06 - - - -3.2577 - 1.654 0.276 - 38.7 1 2 1 -0.0079 21 0 0 0 1.54E+07 8.65E+06 - - - 1.7925 1 221125_WJC_METTL3_EV_vs_WT_F10.11028.11028.3 2.09E-10 15/80 K.TVETRDGQVINETSQHHDDLE.- sp|P08670|VIME_HUMAN 1 2422.0997 2.13 142830 11028 3 2422.097768 808.3738 Vimentin OS=Homo sapiens OX=9606 GN=VIM PE=1 SV=4 4.44 2238.2 - 524422 - - - -0.7869 - 3.49 0.696 - 226.4 1 2 1 -0.0019 21 0 0 0 4.89E+06 2.30E+06 - - - 9.2958 0.9993 221125_WJC_METTL3_EV_vs_WT_F10.11030.11030.4 0.0161 Sep-90 K.AGDK[136.11]PHMQTYEVDLNK[136.11].C "sp|P21912|SDHB_HUMAN,tr|A0A087WWT1|A0A087WWT1_HUMAN" 2 1860.9011 0.41 142832 11030 4 1860.898943 466.2326 "Succinate dehydrogenase [ubiquinone] iron-sulfur subunit, mitochondrial OS=Homo sapiens OX=9606 GN=SDHB PE=1 SV=3" 5.38 2238.4 - 301657 - - - -1.158 - 1.979 0.313 - 49.7 1 2 0 -0.0022 16 0 0 0 2.83E+06 6.83E+06 - - - 2.1902 0.9997 221125_WJC_METTL3_EV_vs_WT_F10.11032.11032.3 1.72E-05 Nov-44 R.TNTPVK[136.11]EDWNVR[166.11].L "sp|P78347|GTF2I_HUMAN,tr|A0A494C0Q7|A0A494C0Q7_HUMAN,tr|A0A494C1K3|A0A494C1K3_HUMAN" 3 1475.7488 3.41 142834 11032 3 1475.750407 492.9235 General transcription factor II-I OS=Homo sapiens OX=9606 GN=GTF2I PE=1 SV=2 5.74 2238.7 - 151604 - - - 1.1147 - 2.113 0.481 - 121 1 2 1 0.0016 12 0 0 0 7.35E+06 2.16E+06 - - - 5.9759 1 221125_WJC_METTL3_EV_vs_WT_F10.11035.11035.3 9.40E-05 19/72 R.SGDPR[166.11]PQAAEPPDHLTITR[166.11].R "sp|Q96L14|C170L_HUMAN,sp|Q5SW79|CE170_HUMAN,tr|H0Y2V6|H0Y2V6_HUMAN,tr|E7EMW0|E7EMW0_HUMAN,tr|H0Y4T4|H0Y4T4_HUMAN,tr|E7EWM2|E7EWM2_HUMAN,tr|E5RG47|E5RG47_HUMAN" 7 2077.0456 1.54 142835 11035 3 2077.046012 693.3558 Cep170-like protein OS=Homo sapiens OX=9606 GN=CEP170P1 PE=5 SV=2 5.36 2239.1 - 481848 - - - 0.2195 - 3.405 0.541 - 367.2 1 2 0 0.0005 19 0 0 0 1.47E+07 9.52E+06 - - - 7.5817 0.9999 221125_WJC_METTL3_EV_vs_WT_F10.11038.11038.3 1.66E-06 Nov-88 K.VAEQC[160.03]EPAESQPEALSEKEDVC[160.03]K.T "sp|P82094|TMF1_HUMAN,tr|F8WF45|F8WF45_HUMAN,tr|A0A2R8Y7M0|A0A2R8Y7M0_HUMAN" 3 2632.1633 1.79 142838 11038 3 2632.163131 878.395 TATA element modulatory factor OS=Homo sapiens OX=9606 GN=TMF1 PE=1 SV=2 4.06 2239.5 - 172050 - - - -0.0501 - 2.325 0.591 - 91.4 1 2 1 -0.0001 23 0 0 0 5.26E+07 2.94E+07 - - - 7.1083 0.9998 221125_WJC_METTL3_EV_vs_WT_F10.11039.11039.3 0.000668 Jun-68 R.K[136.11]PEEEEEEELEETAQEK[136.11]K[136.11].L sp|O43818|U3IP2_HUMAN 1 2227.0442 1.64 142839 11039 3 2227.042052 743.3553 U3 small nucleolar RNA-interacting protein 2 OS=Homo sapiens OX=9606 GN=RRP9 PE=1 SV=1 4.12 2239.6 - 146509 - - - -0.9569 - 1.43 0.456 - 32.2 1 2 0 -0.0021 18 0 0 0 1.27E+06 7.73E+05 - - - 4.514 0.9999 221125_WJC_METTL3_EV_vs_WT_F10.11042.11042.3 1.47E-06 13/64 R.GGSDDSSKDPIDVNYEK.L "sp|P09874|PARP1_HUMAN,tr|A0A7I2V3E1|A0A7I2V3E1_HUMAN" 2 1824.8014 1.13 142840 11042 3 1824.801951 609.2744 Poly [ADP-ribose] polymerase 1 OS=Homo sapiens OX=9606 GN=PARP1 PE=1 SV=4 4.04 2240.1 - 2.48E+06 - - - 0.32 - 2.453 0.539 - 154.9 1 2 1 0.0006 17 0 0 0 3.20E+08 2.83E+08 - - - 6.816 1 221125_WJC_METTL3_EV_vs_WT_F10.11043.11043.3 1.31E-10 16/64 R.GGSDDSSK[136.11]DPIDVNYEK[136.11].L "sp|P09874|PARP1_HUMAN,tr|A0A7I2V3E1|A0A7I2V3E1_HUMAN" 2 1840.8298 1.13 142841 11043 3 1840.828727 614.6172 Poly [ADP-ribose] polymerase 1 OS=Homo sapiens OX=9606 GN=PARP1 PE=1 SV=4 4.04 2240.1 - 2.46E+06 - - - -0.565 - 3.017 0.641 - 346.6 1 2 1 -0.001 17 0 0 0 3.20E+08 2.83E+08 - - - 8.4759 0.9999 221125_WJC_METTL3_EV_vs_WT_F10.11050.11050.3 2.52E-05 Jul-80 K.TVETR[166.11]DGQVINETSQHHDDLE.- sp|P08670|VIME_HUMAN 1 2432.1079 2.13 142848 11050 3 2432.107787 811.7099 Vimentin OS=Homo sapiens OX=9606 GN=VIM PE=1 SV=4 4.44 2241 - 219991 - - - -0.0646 - 2.015 0.607 - 43.4 1 2 1 -0.0002 21 0 0 0 4.89E+06 2.30E+06 - - - 6.9871 1 221125_WJC_METTL3_EV_vs_WT_F10.11051.11051.4 5.61E-09 13/114 R.DTHPGSPGSPGPALRPLPAR.E sp|Q8N0Y2|ZN444_HUMAN 1 1979.0337 1.45 142849 11051 4 1979.037519 495.7657 Zinc finger protein 444 OS=Homo sapiens OX=9606 GN=ZNF444 PE=1 SV=1 9.61 2241.1 - 201011 - - - 1.9262 - 2.816 0.555 - 104.7 1 2 0 0.0038 20 0 0 0 2.67E+06 1.84E+06 - - - 4.4018 0.9976 221125_WJC_METTL3_EV_vs_WT_F10.11052.11052.4 0.0101 11/114 R.DTHPGSPGSPGPALR[166.11]PLPAR[166.11].E sp|Q8N0Y2|ZN444_HUMAN 1 1999.0502 1.47 142850 11052 4 1999.053212 500.7698 Zinc finger protein 444 OS=Homo sapiens OX=9606 GN=ZNF444 PE=1 SV=1 9.61 2241.3 - 184778 - - - 1.4832 - 1.787 0.269 - 80.3 1 2 0 0.003 20 0 0 0 2.67E+06 1.82E+06 - - - 1.7606 1 221125_WJC_METTL3_EV_vs_WT_F10.11057.11057.3 2.40E-11 20/72 K.SC[160.03]SGVEFSTSGHAYTDTGK[136.11].A "sp|Q9Y277|VDAC3_HUMAN,tr|E5RHE1|E5RHE1_HUMAN,tr|E5RJN6|E5RJN6_HUMAN,tr|E5RHZ6|E5RHZ6_HUMAN" 4 1997.8516 1.14 142853 11057 3 1997.854369 666.9578 Voltage-dependent anion-selective channel protein 3 OS=Homo sapiens OX=9606 GN=VDAC3 PE=1 SV=1 5.3 2241.9 - 654339 - - - 1.3685 - 3.919 0.687 - 620.4 1 2 0 0.0027 19 0 0 0 3.98E+07 3.48E+07 - - - 9.5542 1 221125_WJC_METTL3_EV_vs_WT_F10.11058.11058.3 1.93E-15 25/72 K.SC[160.03]SGVEFSTSGHAYTDTGK.A "sp|Q9Y277|VDAC3_HUMAN,tr|E5RHE1|E5RHE1_HUMAN,tr|E5RJN6|E5RJN6_HUMAN,tr|E5RHZ6|E5RHZ6_HUMAN" 4 1989.8374 1.15 142854 11058 3 1989.836138 664.2864 Voltage-dependent anion-selective channel protein 3 OS=Homo sapiens OX=9606 GN=VDAC3 PE=1 SV=1 5.3 2242.1 - 616601 - - - -0.6518 - 4.828 0.756 - 1134.8 1 2 0 -0.0013 19 0 0 0 3.98E+07 3.47E+07 - - - 10.8364 1 221125_WJC_METTL3_EV_vs_WT_F10.11062.11062.4 1.29E-08 13/138 R.SVGAPGGAPTPALGPSAPQKPLRR.A sp|Q9P206|K1522_HUMAN 1 2281.2655 0.89 142858 11062 4 2281.266593 571.3237 Uncharacterized protein KIAA1522 OS=Homo sapiens OX=9606 GN=KIAA1522 PE=1 SV=2 12.01 2242.6 - 328239 - - - 0.48 - 2.966 0.588 - 103 1 2 0 0.0011 24 0 0 0 5.10E+06 5.74E+06 - - - 4.6926 1 221125_WJC_METTL3_EV_vs_WT_F10.11063.11063.3 7.36E-08 23/88 R.APSPAPSSVPLGSEK[136.11]PSNVSQDR[166.11].K "sp|O75179|ANR17_HUMAN,tr|H0YM23|H0YM23_HUMAN" 2 2324.1727 3.29 142859 11063 3 2324.171819 775.7315 Ankyrin repeat domain-containing protein 17 OS=Homo sapiens OX=9606 GN=ANKRD17 PE=1 SV=3 6.11 2242.7 - 259205 - - - -0.389 - 4.028 0.572 - 586.8 1 2 0 -0.0009 23 0 0 0 8.29E+07 2.52E+07 - - - 8.1855 0.9999 221125_WJC_METTL3_EV_vs_WT_F10.11065.11065.3 0.000348 13/92 K.SLAGSSGPGASSGTSGDHGELVVR.L "sp|P29692|EF1D_HUMAN,tr|E9PI39|E9PI39_HUMAN,tr|E9PMW7|E9PMW7_HUMAN,tr|E9PQ49|E9PQ49_HUMAN,tr|A0A087X1X7|A0A087X1X7_HUMAN,tr|E9PL12|E9PL12_HUMAN,tr|H0YCK7|H0YCK7_HUMAN,tr|E9PIZ1|E9PIZ1_HUMAN,tr|E9PPR1|E9PPR1_HUMAN,tr|E9PRY8|E9PRY8_HUMAN,tr|E9PK01|E9PK01_HUMAN" 11 2184.0407 3.43 142861 11065 3 2184.043631 729.0208 Elongation factor 1-delta OS=Homo sapiens OX=9606 GN=EEF1D PE=1 SV=5 5.3 2243 - 177720 - - - 1.3406 - 2.999 0.452 - 90 1 2 0 0.0029 24 0 0 0 1.61E+06 4.68E+05 - - - 6.1294 1 221125_WJC_METTL3_EV_vs_WT_F10.11066.11066.2 8.18E-08 Sep-32 R.GGSDDSSKDPIDVNYEK.L "sp|P09874|PARP1_HUMAN,tr|A0A7I2V3E1|A0A7I2V3E1_HUMAN" 2 1824.8014 1.09 142862 11066 2 1824.801317 913.408 Poly [ADP-ribose] polymerase 1 OS=Homo sapiens OX=9606 GN=PARP1 PE=1 SV=4 4.04 2243.1 - 123774 - - - -0.0274 - 2.559 0.716 - 187.1 1 2 1 -0.0001 17 0 0 0 8.80E+06 8.05E+06 - - - 6.6395 1 221125_WJC_METTL3_EV_vs_WT_F10.11071.11071.3 2.20E-13 30/88 R.APSPAPSSVPLGSEKPSNVSQDR.K "sp|O75179|ANR17_HUMAN,tr|H0YM23|H0YM23_HUMAN" 2 2306.1503 3.29 142865 11071 3 2306.152638 769.724 Ankyrin repeat domain-containing protein 17 OS=Homo sapiens OX=9606 GN=ANKRD17 PE=1 SV=3 6.11 2243.8 - 1.88E+06 - - - 1.0342 - 5.267 0.598 - 1063.8 1 2 0 0.0024 23 0 0 0 8.29E+07 2.52E+07 - - - 9.1041 0.9971 221125_WJC_METTL3_EV_vs_WT_F10.11080.11080.4 0.000374 Oct-96 K.TNHPDSASEKNPVTLLK.E "sp|Q8WVK7|SKA2_HUMAN,tr|J3KSP0|J3KSP0_HUMAN,tr|J3QL03|J3QL03_HUMAN" 3 1849.9534 1.96 142872 11080 4 1849.956562 463.4956 Spindle and kinetochore-associated protein 2 OS=Homo sapiens OX=9606 GN=SKA2 PE=1 SV=1 6.42 2244.9 - 341300 - - - 1.7141 - 2.133 0.325 - 54.1 1 2 1 0.0032 17 0 0 0 2.85E+07 1.45E+07 - - - 2.3169 0.9999 221125_WJC_METTL3_EV_vs_WT_F10.11082.11082.4 5.57E-08 21/114 R.TGGIGDSRPPSFHPNVASSR.D "sp|O14640|DVL1_HUMAN,tr|A0A087WWA7|A0A087WWA7_HUMAN" 2 2037.998 0.08 142874 11082 4 2038.002447 510.5068 Segment polarity protein dishevelled homolog DVL-1 OS=Homo sapiens OX=9606 GN=DVL1 PE=1 SV=2 9.29 2245.1 - 434806 - - - 2.1575 - 4.016 0.485 - 297 1 2 0 0.0044 20 0 0 0 5.01E+06 6.51E+07 - - - 3.911 0.9999 221125_WJC_METTL3_EV_vs_WT_F10.11086.11086.3 2.12E-05 Oct-52 R.GHNTNVGAIVFHPK.S sp|O43172|PRP4_HUMAN 1 1489.779 1.68 142878 11086 3 1489.780265 497.6003 U4\U6 small nuclear ribonucleoprotein Prp4 OS=Homo sapiens OX=9606 GN=PRPF4 PE=1 SV=2 8.76 2245.7 - 163654 - - - 0.8518 - 2.193 0.413 - 108.2 1 2 0 0.0013 14 0 0 0 6.50E+06 3.88E+06 - - - 5.2311 0.9997 221125_WJC_METTL3_EV_vs_WT_F10.11092.11092.3 0.00984 13/32 R.EHLLDQLKR.K "sp|P52732|KIF11_HUMAN,tr|A0A7I2V3A9|A0A7I2V3A9_HUMAN" 2 1150.6459 5.18 142882 11092 3 1150.645814 384.5559 Kinesin-like protein KIF11 OS=Homo sapiens OX=9606 GN=KIF11 PE=1 SV=2 6.85 2246.5 - 298506 - - - -0.0365 - 2.449 0.266 - 344.3 1 2 0 0 9 0 0 0 8.12E+06 1.57E+06 - - - 4.205 0.9814 221125_WJC_METTL3_EV_vs_WT_F10.11104.11104.3 1.7 Aug-32 R.EHLLDQLK[136.11]R[166.11].K "sp|P52732|KIF11_HUMAN,tr|A0A7I2V3A9|A0A7I2V3A9_HUMAN" 2 1168.6683 5.18 142892 11104 3 1168.669757 390.5634 Kinesin-like protein KIF11 OS=Homo sapiens OX=9606 GN=KIF11 PE=1 SV=2 6.85 2248 - 118139 - - - 1.2245 - 1.69 0.129 - 81.6 1 2 0 0.0014 9 0 0 0 8.12E+06 1.57E+06 - - - 1.5593 1 221125_WJC_METTL3_EV_vs_WT_F10.11109.11109.3 3.39E-09 19/88 K.VAEQC[160.03]EPAESQPEALSEK[136.11]EDVC[160.03]K[136.11].T "sp|P82094|TMF1_HUMAN,tr|F8WF45|F8WF45_HUMAN,tr|A0A2R8Y7M0|A0A2R8Y7M0_HUMAN" 3 2648.1917 1.79 142895 11109 3 2648.190794 883.7378 TATA element modulatory factor OS=Homo sapiens OX=9606 GN=TMF1 PE=1 SV=2 4.06 2248.6 - 1.89E+06 - - - -0.3281 - 3.381 0.638 - 347.4 1 2 1 -0.0009 23 0 0 0 5.26E+07 2.94E+07 - - - 8.5106 1 221125_WJC_METTL3_EV_vs_WT_F10.11111.11111.3 2.04E-12 20/76 R.YFNK[136.11]NEDVC[160.03]SC[160.03]STDTSEVPR[166.11].W sp|P49790|NU153_HUMAN 1 2425.0281 1.29 142897 11111 3 2425.02383 809.35 Nuclear pore complex protein Nup153 OS=Homo sapiens OX=9606 GN=NUP153 PE=1 SV=2 4.32 2248.9 - 398866 - - - -1.7649 - 3.562 0.784 - 666.4 1 2 1 -0.0043 20 0 0 0 8.17E+06 6.31E+06 - - - 10.3615 0.9998 221125_WJC_METTL3_EV_vs_WT_F10.11113.11113.3 7.70E-07 Oct-64 K.TNHPDSASEK[136.11]NPVTLLK[136.11].E "sp|Q8WVK7|SKA2_HUMAN,tr|J3KSP0|J3KSP0_HUMAN,tr|J3QL03|J3QL03_HUMAN" 3 1865.9818 1.78 142899 11113 3 1865.979728 623.0012 Spindle and kinetochore-associated protein 2 OS=Homo sapiens OX=9606 GN=SKA2 PE=1 SV=1 6.42 2249.2 - 303522 - - - -1.1056 - 2.232 0.519 - 95.1 1 2 1 -0.0021 17 0 0 0 1.87E+07 1.05E+07 - - - 6.3541 1 221125_WJC_METTL3_EV_vs_WT_F10.11118.11118.3 8.83E-11 18/76 R.YFNKNEDVC[160.03]SC[160.03]STDTSEVPR.W sp|P49790|NU153_HUMAN 1 2407.0056 1.29 142902 11118 3 2407.00619 803.3425 Nuclear pore complex protein Nup153 OS=Homo sapiens OX=9606 GN=NUP153 PE=1 SV=2 4.32 2249.8 - 595745 - - - 0.2285 - 3.547 0.725 - 478.3 1 2 1 0.0006 20 0 0 0 8.17E+06 6.31E+06 - - - 9.6945 0.9999 221125_WJC_METTL3_EV_vs_WT_F10.11119.11119.3 1.62E-09 14/64 K.TNHPDSASEKNPVTLLK.E "sp|Q8WVK7|SKA2_HUMAN,tr|J3KSP0|J3KSP0_HUMAN,tr|J3QL03|J3QL03_HUMAN" 3 1849.9534 1.78 142903 11119 3 1849.952675 617.6584 Spindle and kinetochore-associated protein 2 OS=Homo sapiens OX=9606 GN=SKA2 PE=1 SV=1 6.42 2250 - 789899 - - - -0.387 - 2.696 0.591 - 196.9 1 2 1 -0.0007 17 0 0 0 1.87E+07 1.05E+07 - - - 7.6344 0.9999 221125_WJC_METTL3_EV_vs_WT_F10.11120.11120.4 6.65E-08 15/96 K.TNHPDSASEK[136.11]NPVTLLK[136.11].E "sp|Q8WVK7|SKA2_HUMAN,tr|J3KSP0|J3KSP0_HUMAN,tr|J3QL03|J3QL03_HUMAN" 3 1865.9818 2.02 142904 11120 4 1865.982929 467.5027 Spindle and kinetochore-associated protein 2 OS=Homo sapiens OX=9606 GN=SKA2 PE=1 SV=1 6.42 2250.1 - 609177 - - - 0.6099 - 2.499 0.571 - 139.1 1 2 1 0.0011 17 0 0 0 2.92E+07 1.45E+07 - - - 4.5137 0.9991 221125_WJC_METTL3_EV_vs_WT_F10.11131.11131.4 0.00172 10/114 R.YLTEHPDPNNENIVGYNNK[136.11]K[136.11].C sp|Q6P2Q9|PRP8_HUMAN 1 2374.1524 1.35 142913 11131 4 2374.158663 594.5454 Pre-mRNA-processing-splicing factor 8 OS=Homo sapiens OX=9606 GN=PRPF8 PE=1 SV=2 5.45 2251.6 - 476223 - - - 2.622 - 1.8 0.354 - 40.6 1 2 0 0.0062 20 0 0 0 4.87E+07 3.60E+07 - - - 2.502 0.9974 221125_WJC_METTL3_EV_vs_WT_F10.11135.11135.2 0.00632 Aug-32 R.GGSDDSSK[136.11]DPIDVNYEK[136.11].L "sp|P09874|PARP1_HUMAN,tr|A0A7I2V3E1|A0A7I2V3E1_HUMAN" 2 1840.8298 1.09 142916 11135 2 1840.830182 921.4222 Poly [ADP-ribose] polymerase 1 OS=Homo sapiens OX=9606 GN=PARP1 PE=1 SV=4 4.04 2252.1 - 142235 - - - 0.2254 - 1.916 0.441 - 217.2 1 2 1 0.0004 17 0 0 0 8.80E+06 8.05E+06 - - - 3.8967 1 221125_WJC_METTL3_EV_vs_WT_F10.11160.11160.3 2.12E-11 16/76 R.YLTEHPDPNNENIVGYNNKK.C sp|Q6P2Q9|PRP8_HUMAN 1 2358.124 1.44 142936 11160 3 2358.130716 787.0486 Pre-mRNA-processing-splicing factor 8 OS=Homo sapiens OX=9606 GN=PRPF8 PE=1 SV=2 5.45 2255.2 - 331595 - - - 2.8319 - 3.141 0.724 - 252.1 1 2 0 0.0067 20 0 0 0 1.19E+07 8.30E+06 - - - 9.3867 0.9999 221125_WJC_METTL3_EV_vs_WT_F10.11172.11172.4 9.92E-06 Dec-84 R.LK[136.11]GSGNLEAIHIIK[136.11]K[136.11].L "sp|P78371|TCPB_HUMAN,tr|F8VQ14|F8VQ14_HUMAN,tr|F5GWF6|F5GWF6_HUMAN" 3 1644.0149 0.45 142946 11172 4 1644.015873 412.011 T-complex protein 1 subunit beta OS=Homo sapiens OX=9606 GN=CCT2 PE=1 SV=4 9.7 2256.9 - 470236 - - - 0.6064 - 2.14 0.533 - 85.7 1 2 1 0.001 15 0 0 0 9.14E+06 2.05E+07 - - - 4.1372 1 221125_WJC_METTL3_EV_vs_WT_F10.11173.11173.3 5.57E-08 15/76 R.YLTEHPDPNNENIVGYNNK[136.11]K[136.11].C sp|Q6P2Q9|PRP8_HUMAN 1 2374.1524 1.44 142947 11173 3 2374.154396 792.3914 Pre-mRNA-processing-splicing factor 8 OS=Homo sapiens OX=9606 GN=PRPF8 PE=1 SV=2 5.45 2257 - 342460 - - - 0.8247 - 3.151 0.576 - 203.1 1 2 0 0.002 20 0 0 0 1.19E+07 8.30E+06 - - - 7.7457 0.999 221125_WJC_METTL3_EV_vs_WT_F10.11180.11180.4 0.000747 13/114 R.YLTEHPDPNNENIVGYNNKK.C sp|Q6P2Q9|PRP8_HUMAN 1 2358.124 1.32 142952 11180 4 2358.131613 590.5383 Pre-mRNA-processing-splicing factor 8 OS=Homo sapiens OX=9606 GN=PRPF8 PE=1 SV=2 5.45 2257.9 - 2.46E+06 - - - 3.2123 - 2.322 0.359 - 104.7 1 2 0 0.0076 20 0 0 0 4.75E+07 3.59E+07 - - - 2.6303 0.9993 221125_WJC_METTL3_EV_vs_WT_F10.11182.11182.3 5.35E-06 Dec-64 K.NK[136.11]DK[136.11]YVGVSSDSVGGFR[166.11].Y sp|Q14677|EPN4_HUMAN 1 1839.9325 1.81 142954 11182 3 1839.938379 614.3181 Clathrin interactor 1 OS=Homo sapiens OX=9606 GN=CLINT1 PE=1 SV=1 8.5 2258.1 - 280738 - - - 3.1702 - 2.459 0.5 - 166.2 1 2 2 0.0058 17 0 0 0 1.08E+07 5.97E+06 - - - 6.3859 0.9993 221125_WJC_METTL3_EV_vs_WT_F10.11183.11183.4 0.00604 Dec-84 R.LKGSGNLEAIHIIKK.L "sp|P78371|TCPB_HUMAN,tr|F8VQ14|F8VQ14_HUMAN,tr|F5GWF6|F5GWF6_HUMAN" 3 1619.9723 0.45 142955 11183 4 1619.976576 406.0003 T-complex protein 1 subunit beta OS=Homo sapiens OX=9606 GN=CCT2 PE=1 SV=4 9.7 2258.3 - 248186 - - - 2.6544 - 2.595 0.436 - 95 1 2 1 0.0043 15 0 0 0 9.14E+06 2.05E+07 - - - 3.361 0.9967 221125_WJC_METTL3_EV_vs_WT_F10.11184.11184.4 0.00159 Aug-90 R.NEC[160.03]FLQHKDDNPNLPR.L "sp|P02768|ALBU_HUMAN,tr|A0A087WWT3|A0A087WWT3_HUMAN,tr|H7C013|H7C013_HUMAN,tr|A0A0C4DGB6|A0A0C4DGB6_HUMAN" 4 1995.9221 23.58 142956 11184 4 1995.927129 499.9878 Albumin OS=Homo sapiens OX=9606 GN=ALB PE=1 SV=2 5.38 2258.4 - 198444 - - - 2.5156 - 1.764 0.352 - 61.8 1 2 1 0.005 16 0 0 0 2.14E+07 9.08E+05 - - - 2.4884 0.9207 221125_WJC_METTL3_EV_vs_WT_F10.11191.11191.2 1.07 16-Apr R.NIVEAAAVR.D "sp|Q5JNZ5|RS26L_HUMAN,sp|P62854|RS26_HUMAN" 2 941.5294 0.49 142961 11191 2 941.532546 471.772 Putative 40S ribosomal protein S26-like 1 OS=Homo sapiens OX=9606 GN=RPS26P11 PE=5 SV=1 6 2259.3 - 129812 - - - 3.3095 - 0.959 0.258 - 36.7 11 2 0 0.0031 9 0 0 0 2.07E+06 4.27E+06 - - - 0.3593 0.9993 221125_WJC_METTL3_EV_vs_WT_F10.11193.11193.4 8.48E-05 Oct-90 K.SGDKNDDGLVEIKVDK.L tr|A8MXP9|A8MXP9_HUMAN 1 1730.8687 1.55 142963 11193 4 1730.874078 433.7244 Matrin-3 OS=Homo sapiens OX=9606 GN=MATR3 PE=1 SV=1 4.36 2259.6 - 176604 - - - 3.1308 - 1.928 0.479 - 68.9 1 2 2 0.0054 16 0 0 0 3.70E+07 2.39E+07 - - - 3.625 0.9999 221125_WJC_METTL3_EV_vs_WT_F10.11194.11194.3 1.07E-07 Oct-64 K.NKDVLQAETSQQLC[160.03]C[160.03]QK.F "sp|Q9UNH7|SNX6_HUMAN,tr|A0A0A0MRI2|A0A0A0MRI2_HUMAN" 2 2048.9619 1.37 142964 11194 3 2048.963025 683.9946 Sorting nexin-6 OS=Homo sapiens OX=9606 GN=SNX6 PE=1 SV=1 6.05 2259.7 - 140138 - - - 0.5373 - 2.305 0.548 - 130 1 2 1 0.0011 17 0 0 0 1.85E+07 1.36E+07 - - - 6.759 1 221125_WJC_METTL3_EV_vs_WT_F10.11199.11199.3 5.98E-09 13/76 R.DGEDQTQDTELVETR[166.11]PAGDR[166.11].T "sp|P01889|HLAB_HUMAN,tr|A0A140T951|A0A140T951_HUMAN,tr|Q2L6G2|Q2L6G2_HUMAN,tr|D5H3J5|D5H3J5_HUMAN,tr|S6AU73|S6AU73_HUMAN,tr|A0A140T9G0|A0A140T9G0_HUMAN,tr|A0A140T9H3|A0A140T9H3_HUMAN,tr|Q5SS57|Q5SS57_HUMAN,tr|D9J307|D9J307_HUMAN,tr|A0A140T9A9|A0A140T9A9_HUMAN,tr|A0A140T9S9|A0A140T9S9_HUMAN" 11 2251.0104 1.61 142967 11199 3 2251.015396 751.3441 "HLA class I histocompatibility antigen, B alpha chain OS=Homo sapiens OX=9606 GN=HLA-B PE=1 SV=3" 3.9 2260.4 - 157617 - - - 2.2408 - 2.824 0.661 - 187.8 1 2 0 0.005 20 0 0 0 4.85E+06 3.02E+06 - - - 8.4267 0.9999 221125_WJC_METTL3_EV_vs_WT_F10.11201.11201.3 3.46E-09 13/60 R.NEC[160.03]FLQHKDDNPNLPR.L "sp|P02768|ALBU_HUMAN,tr|A0A087WWT3|A0A087WWT3_HUMAN,tr|H7C013|H7C013_HUMAN,tr|A0A0C4DGB6|A0A0C4DGB6_HUMAN" 4 1995.9221 22.56 142969 11201 3 1995.926772 666.3146 Albumin OS=Homo sapiens OX=9606 GN=ALB PE=1 SV=2 5.38 2260.7 - 121666 - - - 2.3368 - 2.935 0.61 - 267.9 1 2 1 0.0047 16 0 0 0 4.53E+06 2.01E+05 - - - 8.1023 0.9999 221125_WJC_METTL3_EV_vs_WT_F10.11205.11205.3 2.12E-07 14/44 R.TNAENEFVTIKK.D sp|P04264|K2C1_HUMAN 1 1392.7249 242.57 142971 11205 3 1392.729022 465.2489 "Keratin, type II cytoskeletal 1 OS=Homo sapiens OX=9606 GN=KRT1 PE=1 SV=6" 5.81 2261.3 - 845503 - - - 2.9633 - 2.396 0.572 - 288.6 1 2 0 0.0041 12 0 0 0 4.65E+07 1.92E+05 - - - 7.3381 0.9998 221125_WJC_METTL3_EV_vs_WT_F10.11206.11206.4 4.73E-07 13/90 K.SGDK[136.11]NDDGLVEIK[136.11]VDK[136.11].L tr|A8MXP9|A8MXP9_HUMAN 1 1754.9113 1.55 142972 11206 4 1754.915987 439.7351 Matrin-3 OS=Homo sapiens OX=9606 GN=MATR3 PE=1 SV=1 4.36 2261.4 - 505796 - - - 2.6942 - 2.218 0.553 - 119 1 2 2 0.0047 16 0 0 0 3.70E+07 2.39E+07 - - - 4.3186 0.9172 221125_WJC_METTL3_EV_vs_WT_F10.11212.11212.4 0.000783 13/114 R.MSVTEGGIKYPETTEGGRPK.L "sp|P24928|RPB1_HUMAN,tr|A0A6Q8PGB0|A0A6Q8PGB0_HUMAN" 2 2136.0521 1.46 142976 11212 4 2136.061962 535.0203 DNA-directed RNA polymerase II subunit RPB1 OS=Homo sapiens OX=9606 GN=POLR2A PE=1 SV=2 5.99 2262.2 - 277875 - - - 4.608 - 2.393 0.254 - 83.7 1 2 1 0.0098 20 0 0 0 9.15E+06 6.25E+06 - - - 1.7258 0.9999 221125_WJC_METTL3_EV_vs_WT_F10.11219.11219.3 3.02E-06 16/76 R.QFQGHTDGASC[160.03]IDISNDGTK.L "sp|Q04727|TLE4_HUMAN,sp|Q04724|TLE1_HUMAN" 2 2149.9335 1.37 142981 11219 3 2149.943026 717.6518 Transducin-like enhancer protein 4 OS=Homo sapiens OX=9606 GN=TLE4 PE=1 SV=3 4.41 2263.2 - 640112 - - - 4.449 - 2.968 0.587 - 247.8 1 2 0 0.0096 20 0 0 0 1.25E+07 9.19E+06 - - - 7.7211 0.9996 221125_WJC_METTL3_EV_vs_WT_F10.11220.11220.3 0.000612 13/60 K.SGDK[136.11]NDDGLVEIK[136.11]VDK[136.11].L tr|A8MXP9|A8MXP9_HUMAN 1 1754.9113 1.43 142982 11220 3 1754.916007 585.9777 Matrin-3 OS=Homo sapiens OX=9606 GN=MATR3 PE=1 SV=1 4.36 2263.3 - 501673 - - - 2.7055 - 2.56 0.499 - 160.4 1 2 2 0.0047 16 0 0 0 2.02E+07 1.42E+07 - - - 6.514 0.9969 221125_WJC_METTL3_EV_vs_WT_F10.11221.11221.3 5.88E-05 Sep-44 K.HKLDVTSVEDYK.A "sp|P48643|TCPE_HUMAN,tr|E9PCA1|E9PCA1_HUMAN,tr|B7ZAR1|B7ZAR1_HUMAN,tr|E7ENZ3|E7ENZ3_HUMAN" 4 1432.7198 0.62 142983 11221 3 1432.7256 478.5805 T-complex protein 1 subunit epsilon OS=Homo sapiens OX=9606 GN=CCT5 PE=1 SV=1 5.38 2263.4 - 167696 - - - 4.042 - 1.977 0.444 - 133.2 1 2 1 0.0058 12 0 0 0 8.93E+07 1.44E+08 - - - 5.3778 0.999 221125_WJC_METTL3_EV_vs_WT_F10.11222.11222.3 0.000338 Jul-84 K.ASEQETAK[136.11]EEDGSVELESQVQK[136.11].D "sp|Q96B23|CR025_HUMAN,tr|A0A087WVF1|A0A087WVF1_HUMAN,tr|K7EQH1|K7EQH1_HUMAN" 3 2436.1475 1.14 142984 11222 3 2436.143287 813.0564 Uncharacterized protein C18orf25 OS=Homo sapiens OX=9606 GN=C18orf25 PE=1 SV=3 4.06 2263.6 - 123942 - - - -1.7179 - 1.655 0.459 - 62.6 1 2 1 -0.0042 22 0 0 0 1.62E+06 1.42E+06 - - - 4.8507 0.9984 221125_WJC_METTL3_EV_vs_WT_F10.11227.11227.3 0.000412 14/76 R.QFQGHTDGASC[160.03]IDISNDGTK[136.11].L "sp|Q04727|TLE4_HUMAN,sp|Q04724|TLE1_HUMAN" 2 2157.9477 1.24 142987 11227 3 2157.960084 720.3232 Transducin-like enhancer protein 4 OS=Homo sapiens OX=9606 GN=TLE4 PE=1 SV=3 4.41 2264.3 - 988031 - - - 5.7569 - 2.151 0.478 - 156.2 1 2 0 0.0124 20 0 0 0 1.14E+07 9.19E+06 - - - 5.724 1 221125_WJC_METTL3_EV_vs_WT_F10.11228.11228.3 6.16E-10 18/64 K.NK[136.11]DVLQAETSQQLC[160.03]C[160.03]QK[136.11].F "sp|Q9UNH7|SNX6_HUMAN,tr|A0A0A0MRI2|A0A0A0MRI2_HUMAN" 2 2064.9903 1.47 142988 11228 3 2064.993784 689.3374 Sorting nexin-6 OS=Homo sapiens OX=9606 GN=SNX6 PE=1 SV=1 6.05 2264.4 - 472851 - - - 1.6756 - 3.959 0.648 - 517.4 1 2 1 0.0035 17 0 0 0 1.85E+07 1.26E+07 - - - 9.2398 0.9921 221125_WJC_METTL3_EV_vs_WT_F10.11230.11230.3 0.000145 13/60 K.QAQTQTSPEHLVLQQK.Q "sp|Q9ULV3|CIZ1_HUMAN,tr|Q5SYW2|Q5SYW2_HUMAN,tr|F5H2X7|F5H2X7_HUMAN,tr|H0Y5D5|H0Y5D5_HUMAN,tr|A0A494C0L7|A0A494C0L7_HUMAN,tr|Q9BTG3|Q9BTG3_HUMAN" 6 1834.9537 3.84 142990 11230 3 1834.965951 612.6585 Cip1-interacting zinc finger protein OS=Homo sapiens OX=9606 GN=CIZ1 PE=1 SV=2 6.75 2264.6 - 249355 - - - 6.6623 - 2.256 0.369 - 192.2 1 2 0 0.0122 16 0 0 0 1.54E+07 4.02E+06 - - - 4.7382 0.9998 221125_WJC_METTL3_EV_vs_WT_F10.11234.11234.3 1.64E-09 15/60 K.SGDKNDDGLVEIKVDK.L tr|A8MXP9|A8MXP9_HUMAN 1 1730.8687 1.43 142992 11234 3 1730.873882 577.9635 Matrin-3 OS=Homo sapiens OX=9606 GN=MATR3 PE=1 SV=1 4.36 2265.2 - 887550 - - - 3.0176 - 2.82 0.584 - 243.5 1 2 2 0.0052 16 0 0 0 2.02E+07 1.42E+07 - - - 7.7097 0.9997 221125_WJC_METTL3_EV_vs_WT_F10.11236.11236.4 9.20E-09 15/102 R.QRQPPLLGDHPAEYGEGR.G tr|A0A3B3ITJ4|A0A3B3ITJ4_HUMAN 1 2018.9922 1.32 142994 11236 4 2018.99969 505.7553 Heterogeneous nuclear ribonucleoprotein L (Fragment) OS=Homo sapiens OX=9606 GN=HNRNPL PE=1 SV=1 5.45 2265.5 - 214022 - - - 3.6919 - 2.748 0.59 - 131.2 1 2 1 0.0075 18 0 0 0 6.23E+06 4.73E+06 - - - 4.7056 0.9991 221125_WJC_METTL3_EV_vs_WT_F10.11238.11238.2 0.00145 26-Jul R.SSFYPDGGDQETAK[136.11].T "sp|Q9NYF8|BCLF1_HUMAN,tr|H0YF00|H0YF00_HUMAN,tr|E9PKI6|E9PKI6_HUMAN,tr|A0A1W2PQ43|A0A1W2PQ43_HUMAN,tr|E9PK91|E9PK91_HUMAN,tr|E9PJA7|E9PJA7_HUMAN,tr|E9PK09|E9PK09_HUMAN,tr|E9PQN2|E9PQN2_HUMAN" 8 1508.6511 3.13 142996 11238 2 1508.652784 755.3328 Bcl-2-associated transcription factor 1 OS=Homo sapiens OX=9606 GN=BCLAF1 PE=1 SV=2 4.03 2265.7 - 128719 - - - 1.1374 - 1.13 0.468 - 77.8 1 2 0 0.0017 14 0 0 0 1.24E+07 3.96E+06 - - - 2.8038 1 221125_WJC_METTL3_EV_vs_WT_F10.11242.11242.3 1.76E-11 15/76 Q.ITQIEHEVSSSGQEVQSSAK.E "sp|P35527|K1C9_HUMAN,tr|K7EQQ3|K7EQQ3_HUMAN" 2 2143.0393 2252.75 142998 11242 3 2143.039531 715.3537 "Keratin, type I cytoskeletal 9 OS=Homo sapiens OX=9606 GN=KRT9 PE=1 SV=3" 4.75 2266.3 - 342442 - - - 0.105 - 3.324 0.648 - 273 1 1 0 0.0002 20 0 0 0 1.56E+08 6.90E+04 - - - 8.6786 1 221125_WJC_METTL3_EV_vs_WT_F10.11243.11243.3 1.27E-09 Dec-84 R.SDPLGSTQDHALSQESSEPGC[160.03]R[166.11].V "sp|Q5VZL5|ZMYM4_HUMAN,tr|H7C1I7|H7C1I7_HUMAN" 2 2367.0273 0.45 142999 11243 3 2367.023584 790.0164 Zinc finger MYM-type protein 4 OS=Homo sapiens OX=9606 GN=ZMYM4 PE=1 SV=1 4.31 2266.4 - 176004 - - - -1.5492 - 2.493 0.688 - 124.1 1 2 0 -0.0037 22 0 0 0 2.11E+06 4.70E+06 - - - 8.3752 1 221125_WJC_METTL3_EV_vs_WT_F10.11244.11244.3 2.95E-06 20/88 K.TLSSPSNRPSGETSVPPPPAVGR.M sp|Q8WWM7|ATX2L_HUMAN 1 2289.1713 1.78 143000 11244 3 2289.172288 764.0644 Ataxin-2-like protein OS=Homo sapiens OX=9606 GN=ATXN2L PE=1 SV=2 9.26 2266.6 - 311325 - - - 0.4215 - 3.17 0.42 - 261.1 1 2 0 0.001 23 0 0 0 2.57E+07 1.45E+07 - - - 5.9289 0.9992 221125_WJC_METTL3_EV_vs_WT_F10.11245.11245.3 0.01 Aug-36 R.K[136.11]QDSGHLDLR[166.11].N "sp|Q86U44|MTA70_HUMAN,tr|B4E349|B4E349_HUMAN,tr|F5H6D8|F5H6D8_HUMAN,tr|B4DTN4|B4DTN4_HUMAN" 4 1185.6221 0.05 143001 11245 3 1185.622629 396.2146 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 6.75 2266.7 - 269777 - - - 0.442 - 1.547 0.331 - 102.4 1 2 0 0.0005 10 0 0 0 8.69E+05 1.63E+07 - - - 3.5044 0.9999 221125_WJC_METTL3_EV_vs_WT_F10.11252.11252.2 1.83E-06 26-Nov R.SSFYPDGGDQETAK.T "sp|Q9NYF8|BCLF1_HUMAN,tr|H0YF00|H0YF00_HUMAN,tr|E9PKI6|E9PKI6_HUMAN,tr|A0A1W2PQ43|A0A1W2PQ43_HUMAN,tr|E9PK91|E9PK91_HUMAN,tr|E9PJA7|E9PJA7_HUMAN,tr|E9PK09|E9PK09_HUMAN,tr|E9PQN2|E9PQN2_HUMAN" 8 1500.6369 3.13 143006 11252 2 1500.637978 751.3257 Bcl-2-associated transcription factor 1 OS=Homo sapiens OX=9606 GN=BCLAF1 PE=1 SV=2 4.03 2267.6 - 519059 - - - 0.7397 - 1.668 0.616 - 234.8 1 2 0 0.0011 14 0 0 0 1.24E+07 3.96E+06 - - - 4.8743 1 221125_WJC_METTL3_EV_vs_WT_F10.11267.11267.3 1.33E-17 24/84 R.LLEGEDAHLSSQQASGQSYSSR.E sp|P08779|K1C16_HUMAN 1 2349.0833 999 143015 11267 3 2349.084114 784.035 "Keratin, type I cytoskeletal 16 OS=Homo sapiens OX=9606 GN=KRT16 PE=1 SV=4" 4.65 2269.5 - 570787 - - - 0.3482 - 4.19 0.723 - 591.4 1 2 0 0.0008 22 0 0 0 1.91E+08 0.00E+00 - - - 9.9972 0.9984 221125_WJC_METTL3_EV_vs_WT_F10.11277.11277.3 0.0104 Aug-60 K.QQHLSQAFINQHTVER[166.11].K "sp|Q8N5P1|ZC3H8_HUMAN,tr|A0A0C4DGZ1|A0A0C4DGZ1_HUMAN" 2 1944.9794 1.19 143023 11277 3 1944.976683 649.3337 Zinc finger CCCH domain-containing protein 8 OS=Homo sapiens OX=9606 GN=ZC3H8 PE=1 SV=2 6.92 2270.8 - 118916 - - - -1.3851 - 1.635 0.299 - 80.4 1 2 0 -0.0027 16 0 0 0 4.54E+06 3.82E+06 - - - 3.1343 0.9997 221125_WJC_METTL3_EV_vs_WT_F10.11283.11283.3 9.59E-06 Sep-64 R.GGSDDSSKDPIDVNYEK.L "sp|P09874|PARP1_HUMAN,tr|A0A7I2V3E1|A0A7I2V3E1_HUMAN" 2 1824.8014 0.83 143027 11283 3 1824.797491 609.2744 Poly [ADP-ribose] polymerase 1 OS=Homo sapiens OX=9606 GN=PARP1 PE=1 SV=4 4.04 2271.5 - 242815 - - - -2.1241 - 1.596 0.618 - 91.5 1 2 1 -0.0039 17 0 0 0 7.13E+06 8.59E+06 - - - 6.6101 0.9999 221125_WJC_METTL3_EV_vs_WT_F10.11287.11287.4 3.19E-05 Dec-90 K.IR[166.11]K[136.11]PTLDK[136.11]PSPETFVK[136.11].S "sp|Q53GQ0|DHB12_HUMAN,tr|A0A1B0GV93|A0A1B0GV93_HUMAN" 2 1889.1076 0.81 143029 11287 4 1889.10758 473.2842 Very-long-chain 3-oxoacyl-CoA reductase OS=Homo sapiens OX=9606 GN=HSD17B12 PE=1 SV=2 9.7 2272 - 297593 - - - -0.0127 - 2.6 0.567 - 85.5 1 2 1 0 16 0 0 0 1.23E+07 1.52E+07 - - - 4.4977 0.9605 221125_WJC_METTL3_EV_vs_WT_F10.11291.11291.3 9.33E-06 Oct-76 A.SSLVSGLNSSASEPAK[136.11]EPAK[136.11].K "sp|Q86U44|MTA70_HUMAN,tr|F5H6D8|F5H6D8_HUMAN,tr|H0YFV6|H0YFV6_HUMAN,tr|B4DTN4|B4DTN4_HUMAN" 4 1974.024 0.001 143033 11291 3 1974.022881 659.0153 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 5.86 2272.5 - 178505 - - - -0.5922 - 2.075 0.452 - 94 1 1 1 -0.0012 20 0 0 0 0.00E+00 6.61E+06 - - - 5.3499 0.9807 221125_WJC_METTL3_EV_vs_WT_F10.11295.11295.4 5.13E-05 13/90 K.IRKPTLDKPSPETFVK.S "sp|Q53GQ0|DHB12_HUMAN,tr|A0A1B0GV93|A0A1B0GV93_HUMAN" 2 1855.0567 0.83 143035 11295 4 1855.057299 464.7715 Very-long-chain 3-oxoacyl-CoA reductase OS=Homo sapiens OX=9606 GN=HSD17B12 PE=1 SV=2 9.7 2273.1 - 402124 - - - 0.3046 - 2.073 0.223 - 83.7 1 2 1 0.0006 16 0 0 0 1.26E+07 1.52E+07 - - - 1.4236 0.9968 221125_WJC_METTL3_EV_vs_WT_F10.11299.11299.3 4.67E-05 14/72 R.QVEKEETNEIQVVNEEPQR.D sp|Q8NBJ4|GOLM1_HUMAN 1 2297.1135 1.91 143037 11299 3 2297.123479 766.7118 Golgi membrane protein 1 OS=Homo sapiens OX=9606 GN=GOLM1 PE=1 SV=1 4.21 2273.5 - 381315 - - - 4.3298 - 2.632 0.417 - 228.4 1 2 1 0.0099 19 0 0 0 1.94E+07 1.01E+07 - - - 5.5639 0.9934 221125_WJC_METTL3_EV_vs_WT_F10.11301.11301.3 0.00416 Sep-60 K.QQHLSQAFINQHTVER.K "sp|Q8N5P1|ZC3H8_HUMAN,tr|A0A0C4DGZ1|A0A0C4DGZ1_HUMAN" 2 1934.9711 1.19 143039 11301 3 1934.964944 645.9976 Zinc finger CCCH domain-containing protein 8 OS=Homo sapiens OX=9606 GN=ZC3H8 PE=1 SV=2 6.92 2273.8 - 137841 - - - -3.1851 - 1.862 0.258 - 69.4 1 2 0 -0.0062 16 0 0 0 4.54E+06 3.82E+06 - - - 3.0098 0.9999 221125_WJC_METTL3_EV_vs_WT_F10.11303.11303.3 0.000229 Nov-88 K.TLSSPSNR[166.11]PSGETSVPPPPAVGR[166.11].M sp|Q8WWM7|ATX2L_HUMAN 1 2309.1879 1.78 143040 11303 3 2309.188451 770.7366 Ataxin-2-like protein OS=Homo sapiens OX=9606 GN=ATXN2L PE=1 SV=2 9.26 2274 - 392593 - - - 0.2546 - 2.375 0.478 - 83.5 1 2 0 0.0006 23 0 0 0 2.57E+07 1.45E+07 - - - 5.8983 0.9933 221125_WJC_METTL3_EV_vs_WT_F10.11305.11305.3 0.00156 Aug-92 K.K[136.11]PAEQAEETAPIEATATK[136.11]EEEGSS.- sp|Q8N4Q1|MIA40_HUMAN 1 2518.1893 0.35 143041 11305 3 2518.182976 840.4037 Mitochondrial intermembrane space import and assembly protein 40 OS=Homo sapiens OX=9606 GN=CHCHD4 PE=1 SV=1 4.12 2274.2 - 311292 - - - -2.526 - 1.53 0.378 - 41.7 1 2 1 -0.0064 24 0 0 0 3.18E+06 8.97E+06 - - - 3.7403 0.9936 221125_WJC_METTL3_EV_vs_WT_F10.11309.11309.2 0.523 12-Jun R.LAADDFR.T "sp|Q04695|K1C17_HUMAN,sp|P13645|K1C10_HUMAN,sp|O76015|KRT38_HUMAN,sp|Q2M2I5|K1C24_HUMAN,sp|Q15323|K1H1_HUMAN,sp|P02533|K1C14_HUMAN,sp|P05783|K1C18_HUMAN,sp|P08727|K1C19_HUMAN,sp|P08779|K1C16_HUMAN,sp|Q7Z3Y7|K1C28_HUMAN,sp|Q14532|K1H2_HUMAN,sp|P19012|K1C15_HUMAN,sp|O76013|KRT36_HUMAN,sp|Q14525|KT33B_HUMAN,sp|Q92764|KRT35_HUMAN,sp|O76014|KRT37_HUMAN,sp|P13646|K1C13_HUMAN,tr|F8VZY9|F8VZY9_HUMAN,tr|K7EPJ9|K7EPJ9_HUMAN,tr|C9JM50|C9JM50_HUMAN,tr|A0A1B0GVI3|A0A1B0GVI3_HUMAN,tr|K7EMD9|K7EMD9_HUMAN,tr|F5GWP8|F5GWP8_HUMAN,tr|K7ERE3|K7ERE3_HUMAN,tr|C4AM86|C4AM86_HUMAN" 25 806.3923 16.09 143043 11309 2 806.390984 404.2034 "Keratin, type I cytoskeletal 17 OS=Homo sapiens OX=9606 GN=KRT17 PE=1 SV=2" 4.21 2274.7 - 198739 - - - -1.591 - 1.307 0.188 - 122.2 1 2 0 -0.0013 7 0 0 0 9.36E+06 5.82E+05 - - - 1.2775 1 221125_WJC_METTL3_EV_vs_WT_F10.11317.11317.3 7.82E-12 17/80 Y.SQAPSQYSQQSSSYGQQSSFR.Q "sp|Q01844|EWS_HUMAN,tr|B0QYJ7|B0QYJ7_HUMAN,tr|B0QYK0|B0QYK0_HUMAN,tr|F8WC90|F8WC90_HUMAN" 4 2337.0258 1.11 143047 11317 3 2337.020689 780.0159 RNA-binding protein EWS OS=Homo sapiens OX=9606 GN=EWSR1 PE=1 SV=1 8.31 2275.8 - 361112 - - - -2.1788 - 3.174 0.744 - 324.3 1 1 0 -0.0051 21 0 0 0 1.04E+07 9.43E+06 - - - 9.6025 0.999 221125_WJC_METTL3_EV_vs_WT_F10.11324.11324.4 0.000812 Dec-90 K.QQHLSQAFINQHTVER[166.11].K "sp|Q8N5P1|ZC3H8_HUMAN,tr|A0A0C4DGZ1|A0A0C4DGZ1_HUMAN" 2 1944.9794 1.05 143051 11324 4 1944.975849 487.2521 Zinc finger CCCH domain-containing protein 8 OS=Homo sapiens OX=9606 GN=ZC3H8 PE=1 SV=2 6.92 2276.7 - 338717 - - - -1.8139 - 2.636 0.3 - 146.1 1 2 0 -0.0035 16 0 0 0 7.86E+06 7.49E+06 - - - 2.1777 0.9999 221125_WJC_METTL3_EV_vs_WT_F10.11326.11326.3 4.93E-05 Dec-48 R.SLENYHFVDEHGK.D sp|Q14677|EPN4_HUMAN 1 1573.7161 0.93 143053 11326 3 1573.719372 525.5793 Clathrin interactor 1 OS=Homo sapiens OX=9606 GN=CLINT1 PE=1 SV=1 5.26 2277 - 206880 - - - 2.0658 - 2.281 0.46 - 128.6 1 2 0 0.0033 13 0 0 0 6.57E+06 7.04E+06 - - - 5.9034 0.9969 221125_WJC_METTL3_EV_vs_WT_F10.11327.11327.3 0.0251 Aug-48 R.SLENYHFVDEHGK[136.11].D sp|Q14677|EPN4_HUMAN 1 1581.7303 0.93 143054 11327 3 1581.730428 528.2507 Clathrin interactor 1 OS=Homo sapiens OX=9606 GN=CLINT1 PE=1 SV=1 5.26 2277.1 - 174118 - - - 0.0676 - 1.291 0.296 - 53.8 1 2 0 0.0001 13 0 0 0 6.57E+06 7.07E+06 - - - 2.5326 0.983 221125_WJC_METTL3_EV_vs_WT_F10.11328.11328.3 0.00147 Aug-52 K.KSVEEGKIDGIIDK.T sp|Q96A49|SYAP1_HUMAN 1 1529.8301 0.64 143055 11328 3 1529.822435 510.9506 Synapse-associated protein 1 OS=Homo sapiens OX=9606 GN=SYAP1 PE=1 SV=1 4.78 2277.2 - 169958 - - - -5.0025 - 1.791 0.39 - 67.8 1 2 1 -0.0077 14 0 0 0 2.87E+07 4.50E+07 - - - 4.4347 1 221125_WJC_METTL3_EV_vs_WT_F10.11335.11335.3 5.73E-10 17/68 G.R[166.11]AQVQEFC[160.03]DYGTK[136.11]EEC[160.03]MK[136.11].A "sp|Q86U44|MTA70_HUMAN,tr|H0YFV6|H0YFV6_HUMAN" 2 2304.0183 0.001 143060 11335 3 2304.009854 769.0134 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 4.87 2278.2 - 321877 - - - -3.6849 - 3.842 0.695 - 381.8 1 1 1 -0.0085 18 0 0 0 0.00E+00 1.38E+07 - - - 9.6379 0.9998 221125_WJC_METTL3_EV_vs_WT_F10.11337.11337.3 9.37E-05 Dec-64 R.EIVHLQAGQC[160.03]GNQIGAK[136.11].F "sp|P04350|TBB4A_HUMAN,sp|Q9BVA1|TBB2B_HUMAN,sp|P07437|TBB5_HUMAN,sp|Q13509|TBB3_HUMAN,sp|Q13885|TBB2A_HUMAN,sp|P68371|TBB4B_HUMAN,tr|M0R2D3|M0R2D3_HUMAN,tr|G3V3W7|G3V3W7_HUMAN,tr|M0R2T4|M0R2T4_HUMAN,tr|G3V3R4|G3V3R4_HUMAN,tr|M0R042|M0R042_HUMAN,tr|M0QY85|M0QY85_HUMAN,tr|M0QZL7|M0QZL7_HUMAN,tr|G3V5W4|G3V5W4_HUMAN,tr|M0R0X0|M0R0X0_HUMAN,tr|M0QYM7|M0QYM7_HUMAN,tr|G3V4U2|G3V4U2_HUMAN,tr|M0R278|M0R278_HUMAN,tr|M0QY37|M0QY37_HUMAN,tr|G3V2R8|G3V2R8_HUMAN,tr|G3V3J6|G3V3J6_HUMAN,tr|M0QX14|M0QX14_HUMAN,tr|G3V2N6|G3V2N6_HUMAN" 23 1829.9298 0.44 143062 11337 3 1829.926938 610.9839 Tubulin beta-4A chain OS=Homo sapiens OX=9606 GN=TUBB4A PE=1 SV=2 6.83 2278.4 - 263102 - - - -1.5454 - 2.114 0.39 - 132.9 1 2 0 -0.0028 17 0 0 0 1.68E+06 3.84E+06 - - - 4.7785 1 221125_WJC_METTL3_EV_vs_WT_F10.11342.11342.4 8.55E-06 13/72 R.SLENYHFVDEHGK.D sp|Q14677|EPN4_HUMAN 1 1573.7161 1.4 143065 11342 4 1573.715571 394.4363 Clathrin interactor 1 OS=Homo sapiens OX=9606 GN=CLINT1 PE=1 SV=1 5.26 2279.1 - 505438 - - - -0.3495 - 2.08 0.493 - 96.5 1 2 0 -0.0006 13 0 0 0 7.21E+06 5.14E+06 - - - 3.7885 1 221125_WJC_METTL3_EV_vs_WT_F10.11347.11347.3 8.89E-08 16/52 K.K[136.11]PGQSFQEQVEHYR[166.11].D "sp|O15042|SR140_HUMAN,tr|E7ET15|E7ET15_HUMAN,tr|H7C4V2|H7C4V2_HUMAN" 3 1749.8554 0.73 143070 11347 3 1749.854485 584.2924 U2 snRNP-associated SURP motif-containing protein OS=Homo sapiens OX=9606 GN=U2SURP PE=1 SV=2 6.76 2279.7 - 310833 - - - -0.4955 - 3.263 0.51 - 404.7 1 2 0 -0.0009 14 0 0 0 1.41E+07 1.93E+07 - - - 7.3687 0.9964 221125_WJC_METTL3_EV_vs_WT_F10.11349.11349.4 0.0261 11/120 K.KPSAAPEAGASALPNPPALKK.E "sp|P39880|CUX1_HUMAN,tr|A0A2R8Y852|A0A2R8Y852_HUMAN,tr|A0A2R8YDI1|A0A2R8YDI1_HUMAN" 3 2014.1211 1.64 143072 11349 4 2014.117562 504.5376 Homeobox protein cut-like 1 OS=Homo sapiens OX=9606 GN=CUX1 PE=1 SV=3 9.7 2280 - 144542 - - - -1.769 - 1.528 0.26 - 41.2 1 2 0 -0.0036 21 0 0 0 3.21E+06 1.96E+06 - - - 1.6282 0.9999 221125_WJC_METTL3_EV_vs_WT_F10.11357.11357.4 0.000227 14/78 K.K[136.11]PGQSFQEQVEHYR[166.11].D "sp|O15042|SR140_HUMAN,tr|E7ET15|E7ET15_HUMAN,tr|H7C4V2|H7C4V2_HUMAN" 3 1749.8554 0.78 143078 11357 4 1749.852563 438.4711 U2 snRNP-associated SURP motif-containing protein OS=Homo sapiens OX=9606 GN=U2SURP PE=1 SV=2 6.76 2281 - 423695 - - - -1.5938 - 2.674 0.422 - 260.2 1 2 0 -0.0028 14 0 0 0 1.03E+07 1.31E+07 - - - 3.2563 0.9999 221125_WJC_METTL3_EV_vs_WT_F10.11359.11359.4 1.36E-06 9/156 K.VVASVHASISGSSASSTSSTPEVKPLK.S "sp|P52594|AGFG1_HUMAN,tr|B8ZZY2|B8ZZY2_HUMAN,tr|C9J2I0|C9J2I0_HUMAN" 3 2612.3657 2.84 143080 11359 4 2612.37431 654.0987 Arf-GAP domain and FG repeat-containing protein 1 OS=Homo sapiens OX=9606 GN=AGFG1 PE=1 SV=2 8.57 2281.3 - 307050 - - - 3.2863 - 2.182 0.511 - 39.4 1 2 0 0.0086 27 0 0 0 2.71E+06 9.53E+05 - - - 3.9155 1 221125_WJC_METTL3_EV_vs_WT_F10.11364.11364.3 1.23E-09 23/56 R.KDEPDAFKELGTGNR.L sp|P13674|P4HA1_HUMAN 1 1675.8166 1.17 143083 11364 3 1675.816687 559.6128 Prolyl 4-hydroxylase subunit alpha-1 OS=Homo sapiens OX=9606 GN=P4HA1 PE=1 SV=2 4.78 2282 - 1.76E+06 - - - 0.074 - 3.806 0.636 - 728.4 1 2 1 0.0001 15 0 0 0 1.53E+08 1.31E+08 - - - 9.1184 0.9992 221125_WJC_METTL3_EV_vs_WT_F10.11365.11365.4 0.000305 13/84 R.K[136.11]DEPDAFK[136.11]ELGTGNR[166.11].L sp|P13674|P4HA1_HUMAN 1 1701.8532 1.91 143084 11365 4 1701.851656 426.4706 Prolyl 4-hydroxylase subunit alpha-1 OS=Homo sapiens OX=9606 GN=P4HA1 PE=1 SV=2 4.78 2282.1 - 486745 - - - -0.9266 - 1.638 0.392 - 91.1 1 2 1 -0.0016 15 0 0 0 3.64E+07 1.91E+07 - - - 2.8141 0.9982 221125_WJC_METTL3_EV_vs_WT_F10.11367.11367.4 0.000506 Dec-78 K.KSVEEGKIDGIIDK.T sp|Q96A49|SYAP1_HUMAN 1 1529.8301 1.13 143086 11367 4 1529.831507 383.4648 Synapse-associated protein 1 OS=Homo sapiens OX=9606 GN=SYAP1 PE=1 SV=1 4.78 2282.3 - 373574 - - - 0.9276 - 2.544 0.325 - 117.1 1 2 1 0.0014 14 0 0 0 5.39E+06 4.76E+06 - - - 2.3942 0.9994 221125_WJC_METTL3_EV_vs_WT_F10.11368.11368.4 0.00116 13/78 K.K[136.11]SVEEGK[136.11]IDGIIDK[136.11].T sp|Q96A49|SYAP1_HUMAN 1 1553.8727 1.14 143087 11368 4 1553.871251 389.4754 Synapse-associated protein 1 OS=Homo sapiens OX=9606 GN=SYAP1 PE=1 SV=1 4.78 2282.4 - 327241 - - - -0.9248 - 2.478 0.388 - 153.7 1 2 1 -0.0014 14 0 0 0 5.39E+06 4.74E+06 - - - 2.933 0.9999 221125_WJC_METTL3_EV_vs_WT_F10.11374.11374.4 2.97E-05 15/78 K.KPGQSFQEQVEHYR.D "sp|O15042|SR140_HUMAN,tr|E7ET15|E7ET15_HUMAN,tr|H7C4V2|H7C4V2_HUMAN" 3 1731.8329 0.61 143091 11374 4 1731.830492 433.9655 U2 snRNP-associated SURP motif-containing protein OS=Homo sapiens OX=9606 GN=U2SURP PE=1 SV=2 6.76 2283.2 - 620686 - - - -1.38 - 2.631 0.424 - 171.8 1 2 0 -0.0024 14 0 0 0 1.14E+07 1.87E+07 - - - 3.2679 1 221125_WJC_METTL3_EV_vs_WT_F10.11389.11389.3 2.80E-11 26/60 K.HNNQQALSHSIEEGLK.L "sp|Q99496|RING2_HUMAN,tr|X6RFN3|X6RFN3_HUMAN" 2 1803.8864 4.25 143103 11389 3 1803.891601 602.3027 E3 ubiquitin-protein ligase RING2 OS=Homo sapiens OX=9606 GN=RNF2 PE=1 SV=1 6 2284.9 - 2.01E+06 - - - 2.8976 - 4.987 0.691 - 1572.8 1 2 0 0.0052 16 0 0 0 2.03E+08 4.77E+07 - - - 10.3654 1 221125_WJC_METTL3_EV_vs_WT_F10.11390.11390.3 1.80E-12 19/80 K.VLHEAEGHIVTC[160.03]ETNTGEVYR.G "sp|P62318|SMD3_HUMAN,tr|H3BT13|H3BT13_HUMAN" 2 2413.1332 1.74 143104 11390 3 2413.128063 805.385 Small nuclear ribonucleoprotein Sm D3 OS=Homo sapiens OX=9606 GN=SNRPD3 PE=1 SV=1 4.87 2285.1 - 735451 - - - -2.1383 - 3.91 0.65 - 423.3 1 2 0 -0.0052 21 0 0 0 4.85E+07 2.79E+07 - - - 9.0544 1 221125_WJC_METTL3_EV_vs_WT_F10.11392.11392.3 5.21E-09 21/80 K.VLHEAEGHIVTC[160.03]ETNTGEVYR[166.11].G "sp|P62318|SMD3_HUMAN,tr|H3BT13|H3BT13_HUMAN" 2 2423.1415 1.74 143106 11392 3 2423.133226 808.7211 Small nuclear ribonucleoprotein Sm D3 OS=Homo sapiens OX=9606 GN=SNRPD3 PE=1 SV=1 4.87 2285.3 - 467688 - - - -3.4117 - 4.004 0.642 - 465.6 1 2 0 -0.0083 21 0 0 0 4.85E+07 2.79E+07 - - - 9.0213 0.9997 221125_WJC_METTL3_EV_vs_WT_F10.11396.11396.3 0.179 Nov-36 R.LKYENEVALR.Q "sp|P13645|K1C10_HUMAN,tr|A0A1B0GVI3|A0A1B0GVI3_HUMAN" 2 1233.6717 4.23 143108 11396 3 1233.671818 412.2312 "Keratin, type I cytoskeletal 10 OS=Homo sapiens OX=9606 GN=KRT10 PE=1 SV=6" 6.14 2285.9 - 833102 - - - 0.0657 - 2.293 0.41 - 145.4 1 2 1 0.0001 10 0 0 0 2.92E+07 6.89E+06 - - - 5.5346 0.9073 221125_WJC_METTL3_EV_vs_WT_F10.11407.11407.4 5.85 7/114 L.DC[160.03]GYGGLGC[160.03]GYGSFC[160.03]GC[160.03]GYR.G sp|Q3LI67|KRA63_HUMAN 1 2221.8074 21.07 143116 11407 4 2222.807604 556.4591 Keratin-associated protein 6-3 OS=Homo sapiens OX=9606 GN=KRTAP6-3 PE=3 SV=3 5.81 2287.2 - 1.05E+06 - - - 450.1691 - 1.038 0.597 - 15.6 1 1 0 1.0002 20 0 0 0 4.31E+08 2.05E+07 - - - 4.1577 0.9999 221125_WJC_METTL3_EV_vs_WT_F10.11408.11408.4 5.57E-06 14/96 K.EGIKPMWEDDANKNGGK.W "sp|O60573|IF4E2_HUMAN,tr|B4E1E4|B4E1E4_HUMAN,tr|B9A044|B9A044_HUMAN,tr|B8ZZL3|B8ZZL3_HUMAN,tr|B9A023|B9A023_HUMAN,tr|B8ZZ50|B8ZZ50_HUMAN,tr|C9JEL3|C9JEL3_HUMAN" 7 1887.8785 2.5 143117 11408 4 1887.877371 472.9769 Eukaryotic translation initiation factor 4E type 2 OS=Homo sapiens OX=9606 GN=EIF4E2 PE=1 SV=1 4.78 2287.3 - 689236 - - - -0.6044 - 2.738 0.507 - 110.5 1 2 1 -0.0011 17 0 0 0 1.55E+07 6.17E+06 - - - 3.9883 1 221125_WJC_METTL3_EV_vs_WT_F10.11415.11415.4 5.33E-08 24/120 K.VLHEAEGHIVTC[160.03]ETNTGEVYR[166.11].G "sp|P62318|SMD3_HUMAN,tr|H3BT13|H3BT13_HUMAN" 2 2423.1415 6.62 143120 11415 4 2423.136411 606.7926 Small nuclear ribonucleoprotein Sm D3 OS=Homo sapiens OX=9606 GN=SNRPD3 PE=1 SV=1 4.87 2288.2 - 2.47E+06 - - - -2.0973 - 4.365 0.593 - 448.6 1 2 0 -0.0051 21 0 0 0 1.96E+08 2.96E+07 - - - 4.8733 1 221125_WJC_METTL3_EV_vs_WT_F10.11421.11421.3 7.32E-15 25/84 R.ISC[160.03]GGGINVDVNQHPDGGPGGK.A sp|Q96F45|ZN503_HUMAN 1 2133.9862 1.58 143123 11421 3 2133.982936 712.336 Zinc finger protein 503 OS=Homo sapiens OX=9606 GN=ZNF503 PE=1 SV=1 5.21 2289 - 4.92E+06 - - - -1.5131 - 4.837 0.692 - 656.6 1 2 0 -0.0032 22 0 0 0 1.10E+09 6.96E+08 - - - 9.9914 1 221125_WJC_METTL3_EV_vs_WT_F10.11437.11437.3 4.46E-12 26/68 K.RVEAAQETVADYQQTIKK.Y "sp|Q14203|DCTN1_HUMAN,tr|A0A804CDA6|A0A804CDA6_HUMAN,tr|E7EX90|E7EX90_HUMAN,tr|A0A7P0Z4C3|A0A7P0Z4C3_HUMAN,tr|Q6AWB1|Q6AWB1_HUMAN" 5 2077.0804 2.29 143130 11437 3 2077.080843 693.3674 Dynactin subunit 1 OS=Homo sapiens OX=9606 GN=DCTN1 PE=1 SV=3 6.18 2291.2 - 976303 - - - 0.2215 - 4.999 0.598 - 1309.2 1 2 0 0.0005 18 0 0 0 9.14E+07 3.98E+07 - - - 9.2142 1 221125_WJC_METTL3_EV_vs_WT_F10.11442.11442.4 2.38E-10 20/102 K.R[166.11]VEAAQETVADYQQTIK[136.11]K[136.11].Y "sp|Q14203|DCTN1_HUMAN,tr|A0A804CDA6|A0A804CDA6_HUMAN,tr|E7EX90|E7EX90_HUMAN,tr|A0A7P0Z4C3|A0A7P0Z4C3_HUMAN,tr|Q6AWB1|Q6AWB1_HUMAN" 5 2103.1171 1.46 143133 11442 4 2103.112668 526.7865 Dynactin subunit 1 OS=Homo sapiens OX=9606 GN=DCTN1 PE=1 SV=3 6.18 2291.9 - 1.29E+06 - - - -2.085 - 3.824 0.554 - 394.2 1 2 0 -0.0044 18 0 0 0 6.10E+07 4.17E+07 - - - 4.5063 0.9999 221125_WJC_METTL3_EV_vs_WT_F10.11444.11444.4 6.66E-06 21/90 K.IFVGGIK[136.11]EDTEEHHLR[166.11].D "sp|Q32P51|RA1L2_HUMAN,sp|P09651|ROA1_HUMAN,sp|P22626|ROA2_HUMAN,tr|A0A7I2YQN4|A0A7I2YQN4_HUMAN,tr|A0A7I2YQX9|A0A7I2YQX9_HUMAN,tr|A0A7I2V4N0|A0A7I2V4N0_HUMAN,tr|A0A024RA28|A0A024RA28_HUMAN,tr|A0A7I2V4N1|A0A7I2V4N1_HUMAN,tr|A0A7I2V4I6|A0A7I2V4I6_HUMAN,tr|F8VZ49|F8VZ49_HUMAN,tr|A0A7I2V3R8|A0A7I2V3R8_HUMAN,tr|A0A087WUI2|A0A087WUI2_HUMAN,tr|A0A7I2V4S4|A0A7I2V4S4_HUMAN,tr|F8VTQ5|F8VTQ5_HUMAN,tr|F8W6I7|F8W6I7_HUMAN,tr|A0A7I2V2L6|A0A7I2V2L6_HUMAN,tr|A0A7I2V323|A0A7I2V323_HUMAN,tr|A0A7I2V3W0|A0A7I2V3W0_HUMAN,tr|A0A7I2V5U9|A0A7I2V5U9_HUMAN,tr|A0A2R8Y4L2|A0A2R8Y4L2_HUMAN,tr|A0A7I2V3P1|A0A7I2V3P1_HUMAN,tr|A0A7I2V3P7|A0A7I2V3P7_HUMAN" 22 1896.9813 1.09 143134 11444 4 1896.980509 475.2526 Heterogeneous nuclear ribonucleoprotein A1-like 2 OS=Homo sapiens OX=9606 GN=HNRNPA1L2 PE=2 SV=2 5.36 2292.1 - 507500 - - - -0.407 - 3.382 0.514 - 367.7 1 2 1 -0.0008 16 0 0 0 8.85E+07 8.10E+07 - - - 4.1289 0.9765 221125_WJC_METTL3_EV_vs_WT_F10.11457.11457.2 0.121 16-Aug R.K[136.11]IELFGR[166.11]PH.N sp|Q86U44|MTA70_HUMAN 1 1113.6414 0.001 143139 11457 2 1113.640887 557.828 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 8.75 2293.9 - 493025 - - - -0.4454 - 1.831 0.336 - 209.9 1 1 0 -0.0005 9 0 0 0 0.00E+00 2.02E+07 - - - 3.2724 1 221125_WJC_METTL3_EV_vs_WT_F10.11463.11463.3 1.56E-07 25/68 K.R[166.11]VEAAQETVADYQQTIK[136.11]K[136.11].Y "sp|Q14203|DCTN1_HUMAN,tr|A0A804CDA6|A0A804CDA6_HUMAN,tr|E7EX90|E7EX90_HUMAN,tr|A0A7P0Z4C3|A0A7P0Z4C3_HUMAN,tr|Q6AWB1|Q6AWB1_HUMAN" 5 2103.1171 2.29 143141 11463 3 2103.112014 702.0463 Dynactin subunit 1 OS=Homo sapiens OX=9606 GN=DCTN1 PE=1 SV=3 6.18 2294.8 - 1.98E+06 - - - -2.396 - 4.384 0.569 - 1117.7 1 2 0 -0.005 18 0 0 0 9.14E+07 3.98E+07 - - - 8.5627 0.9999 221125_WJC_METTL3_EV_vs_WT_F10.11469.11469.3 8.95E-09 16/60 K.IFVGGIK[136.11]EDTEEHHLR[166.11].D "sp|Q32P51|RA1L2_HUMAN,sp|P09651|ROA1_HUMAN,sp|P22626|ROA2_HUMAN,tr|A0A7I2YQN4|A0A7I2YQN4_HUMAN,tr|A0A7I2YQX9|A0A7I2YQX9_HUMAN,tr|A0A7I2V4N0|A0A7I2V4N0_HUMAN,tr|A0A024RA28|A0A024RA28_HUMAN,tr|A0A7I2V4N1|A0A7I2V4N1_HUMAN,tr|A0A7I2V4I6|A0A7I2V4I6_HUMAN,tr|F8VZ49|F8VZ49_HUMAN,tr|A0A7I2V3R8|A0A7I2V3R8_HUMAN,tr|A0A087WUI2|A0A087WUI2_HUMAN,tr|A0A7I2V4S4|A0A7I2V4S4_HUMAN,tr|F8VTQ5|F8VTQ5_HUMAN,tr|F8W6I7|F8W6I7_HUMAN,tr|A0A7I2V2L6|A0A7I2V2L6_HUMAN,tr|A0A7I2V323|A0A7I2V323_HUMAN,tr|A0A7I2V3W0|A0A7I2V3W0_HUMAN,tr|A0A7I2V5U9|A0A7I2V5U9_HUMAN,tr|A0A2R8Y4L2|A0A2R8Y4L2_HUMAN,tr|A0A7I2V3P1|A0A7I2V3P1_HUMAN,tr|A0A7I2V3P7|A0A7I2V3P7_HUMAN" 22 1896.9813 0.94 143143 11469 3 1896.97979 633.3344 Heterogeneous nuclear ribonucleoprotein A1-like 2 OS=Homo sapiens OX=9606 GN=HNRNPA1L2 PE=2 SV=2 5.36 2295.6 - 451834 - - - -0.786 - 3.129 0.595 - 303.7 1 2 1 -0.0015 16 0 0 0 2.34E+07 2.49E+07 - - - 8.1002 0.9998 221125_WJC_METTL3_EV_vs_WT_F10.11471.11471.4 0.000698 12/120 K.K[136.11]PSAAPEAGASALPNPPALK[136.11]K[136.11].E "sp|P39880|CUX1_HUMAN,tr|A0A2R8Y852|A0A2R8Y852_HUMAN,tr|A0A2R8YDI1|A0A2R8YDI1_HUMAN" 3 2038.1637 1.55 143144 11471 4 2038.16054 510.5482 Homeobox protein cut-like 1 OS=Homo sapiens OX=9606 GN=CUX1 PE=1 SV=3 9.7 2295.9 - 324460 - - - -1.5627 - 1.917 0.382 - 70.9 1 2 0 -0.0032 21 0 0 0 2.26E+07 1.46E+07 - - - 2.7652 0.9992 221125_WJC_METTL3_EV_vs_WT_F10.11474.11474.4 1.49E-07 22/108 -.MR[166.11]EIVHLQAGQC[160.03]GNQIGAK[136.11].F "sp|P04350|TBB4A_HUMAN,sp|Q9BVA1|TBB2B_HUMAN,sp|P07437|TBB5_HUMAN,sp|Q13509|TBB3_HUMAN,sp|Q13885|TBB2A_HUMAN,sp|P68371|TBB4B_HUMAN,tr|M0R2D3|M0R2D3_HUMAN,tr|G3V3W7|G3V3W7_HUMAN,tr|M0R2T4|M0R2T4_HUMAN,tr|G3V3R4|G3V3R4_HUMAN,tr|M0R042|M0R042_HUMAN,tr|M0QY85|M0QY85_HUMAN,tr|M0QZL7|M0QZL7_HUMAN,tr|G3V5W4|G3V5W4_HUMAN,tr|M0R0X0|M0R0X0_HUMAN,tr|M0QYM7|M0QYM7_HUMAN,tr|G3V4U2|G3V4U2_HUMAN,tr|M0R278|M0R278_HUMAN,tr|M0QY37|M0QY37_HUMAN,tr|G3V2R8|G3V2R8_HUMAN,tr|G3V3J6|G3V3J6_HUMAN,tr|M0QX14|M0QX14_HUMAN,tr|G3V2N6|G3V2N6_HUMAN" 23 2127.0796 0.65 143145 11474 4 2127.070889 532.7772 Tubulin beta-4A chain OS=Homo sapiens OX=9606 GN=TUBB4A PE=1 SV=2 8 2296.2 - 616710 - - - -4.1103 - 3.735 0.504 - 570.1 1 2 1 -0.0087 19 0 0 0 1.80E+07 2.78E+07 - - - 4.0562 1 221125_WJC_METTL3_EV_vs_WT_F10.11476.11476.4 1.28E-10 24/102 K.RVEAAQETVADYQQTIKK.Y "sp|Q14203|DCTN1_HUMAN,tr|A0A804CDA6|A0A804CDA6_HUMAN,tr|E7EX90|E7EX90_HUMAN,tr|A0A7P0Z4C3|A0A7P0Z4C3_HUMAN,tr|Q6AWB1|Q6AWB1_HUMAN" 5 2077.0804 1.49 143146 11476 4 2077.078783 520.2774 Dynactin subunit 1 OS=Homo sapiens OX=9606 GN=DCTN1 PE=1 SV=3 6.18 2296.5 - 2.66E+06 - - - -0.7703 - 4.188 0.593 - 549.1 1 2 0 -0.0016 18 0 0 0 6.07E+07 4.06E+07 - - - 4.8776 0.9997 221125_WJC_METTL3_EV_vs_WT_F10.11489.11489.3 1.94E-05 22/72 -.MR[166.11]EIVHLQAGQC[160.03]GNQIGAK[136.11].F "sp|P04350|TBB4A_HUMAN,sp|Q9BVA1|TBB2B_HUMAN,sp|P07437|TBB5_HUMAN,sp|Q13509|TBB3_HUMAN,sp|Q13885|TBB2A_HUMAN,sp|P68371|TBB4B_HUMAN,tr|M0R2D3|M0R2D3_HUMAN,tr|G3V3W7|G3V3W7_HUMAN,tr|M0R2T4|M0R2T4_HUMAN,tr|G3V3R4|G3V3R4_HUMAN,tr|M0R042|M0R042_HUMAN,tr|M0QY85|M0QY85_HUMAN,tr|M0QZL7|M0QZL7_HUMAN,tr|G3V5W4|G3V5W4_HUMAN,tr|M0R0X0|M0R0X0_HUMAN,tr|M0QYM7|M0QYM7_HUMAN,tr|G3V4U2|G3V4U2_HUMAN,tr|M0R278|M0R278_HUMAN,tr|M0QY37|M0QY37_HUMAN,tr|G3V2R8|G3V2R8_HUMAN,tr|G3V3J6|G3V3J6_HUMAN,tr|M0QX14|M0QX14_HUMAN,tr|G3V2N6|G3V2N6_HUMAN" 23 2127.0796 0.4 143155 11489 3 2127.085743 710.0338 Tubulin beta-4A chain OS=Homo sapiens OX=9606 GN=TUBB4A PE=1 SV=2 8 2298.2 - 478114 - - - 2.873 - 3.568 0.503 - 478.2 1 2 1 0.0061 19 0 0 0 4.84E+06 1.21E+07 - - - 7.2713 0.9999 221125_WJC_METTL3_EV_vs_WT_F10.11490.11490.3 5.52E-10 18/60 K.IFVGGIKEDTEEHHLR.D "sp|Q32P51|RA1L2_HUMAN,sp|P09651|ROA1_HUMAN,sp|P22626|ROA2_HUMAN,tr|A0A7I2YQN4|A0A7I2YQN4_HUMAN,tr|A0A7I2YQX9|A0A7I2YQX9_HUMAN,tr|A0A7I2V4N0|A0A7I2V4N0_HUMAN,tr|A0A024RA28|A0A024RA28_HUMAN,tr|A0A7I2V4N1|A0A7I2V4N1_HUMAN,tr|A0A7I2V4I6|A0A7I2V4I6_HUMAN,tr|F8VZ49|F8VZ49_HUMAN,tr|A0A7I2V3R8|A0A7I2V3R8_HUMAN,tr|A0A087WUI2|A0A087WUI2_HUMAN,tr|A0A7I2V4S4|A0A7I2V4S4_HUMAN,tr|F8VTQ5|F8VTQ5_HUMAN,tr|F8W6I7|F8W6I7_HUMAN,tr|A0A7I2V2L6|A0A7I2V2L6_HUMAN,tr|A0A7I2V323|A0A7I2V323_HUMAN,tr|A0A7I2V3W0|A0A7I2V3W0_HUMAN,tr|A0A7I2V5U9|A0A7I2V5U9_HUMAN,tr|A0A2R8Y4L2|A0A2R8Y4L2_HUMAN,tr|A0A7I2V3P1|A0A7I2V3P1_HUMAN,tr|A0A7I2V3P7|A0A7I2V3P7_HUMAN" 22 1878.9588 0.94 143156 11490 3 1878.957746 627.3269 Heterogeneous nuclear ribonucleoprotein A1-like 2 OS=Homo sapiens OX=9606 GN=HNRNPA1L2 PE=2 SV=2 5.36 2298.3 - 1.21E+06 - - - -0.5668 - 3.186 0.538 - 401.9 1 2 1 -0.0011 16 0 0 0 2.34E+07 2.48E+07 - - - 7.5111 0.9999 221125_WJC_METTL3_EV_vs_WT_F10.11491.11491.4 1.11E-09 23/108 -.MREIVHLQAGQC[160.03]GNQIGAK.F "sp|P04350|TBB4A_HUMAN,sp|Q9BVA1|TBB2B_HUMAN,sp|P07437|TBB5_HUMAN,sp|Q13509|TBB3_HUMAN,sp|Q13885|TBB2A_HUMAN,sp|P68371|TBB4B_HUMAN,tr|M0R2D3|M0R2D3_HUMAN,tr|G3V3W7|G3V3W7_HUMAN,tr|M0R2T4|M0R2T4_HUMAN,tr|G3V3R4|G3V3R4_HUMAN,tr|M0R042|M0R042_HUMAN,tr|M0QY85|M0QY85_HUMAN,tr|M0QZL7|M0QZL7_HUMAN,tr|G3V5W4|G3V5W4_HUMAN,tr|M0R0X0|M0R0X0_HUMAN,tr|M0QYM7|M0QYM7_HUMAN,tr|G3V4U2|G3V4U2_HUMAN,tr|M0R278|M0R278_HUMAN,tr|M0QY37|M0QY37_HUMAN,tr|G3V2R8|G3V2R8_HUMAN,tr|G3V3J6|G3V3J6_HUMAN,tr|M0QX14|M0QX14_HUMAN,tr|G3V2N6|G3V2N6_HUMAN" 23 2109.0572 0.54 143157 11491 4 2109.055538 528.2716 Tubulin beta-4A chain OS=Homo sapiens OX=9606 GN=TUBB4A PE=1 SV=2 8 2298.4 - 717403 - - - -0.77 - 3.946 0.608 - 596.7 1 2 1 -0.0016 19 0 0 0 1.51E+07 2.78E+07 - - - 4.9819 0.9999 221125_WJC_METTL3_EV_vs_WT_F10.11493.11493.4 0.000114 9/126 K.DHTPSQELALTQSVGGDSSADR[166.11].L "sp|Q86U44|MTA70_HUMAN,tr|H0YFV6|H0YFV6_HUMAN" 2 2280.0494 0.01 143159 11493 4 2280.047579 571.0196 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 4.22 2298.7 - 337571 - - - -0.7842 - 2.173 0.478 - 48.8 1 2 0 -0.0018 22 0 0 0 5.20E+04 4.86E+06 - - - 3.64 0.9978 221125_WJC_METTL3_EV_vs_WT_F10.11496.11496.3 0.0526 Jul-36 R.K[136.11]QDSGHLDLR[166.11].N "sp|Q86U44|MTA70_HUMAN,tr|B4E349|B4E349_HUMAN,tr|F5H6D8|F5H6D8_HUMAN,tr|B4DTN4|B4DTN4_HUMAN" 4 1185.6221 0.02 143160 11496 3 1185.620407 396.2146 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 6.75 2299.1 - 260444 - - - -1.4322 - 1.393 0.307 - 71.6 1 2 0 -0.0017 10 0 0 0 4.03E+05 1.75E+07 - - - 2.9303 1 221125_WJC_METTL3_EV_vs_WT_F10.11499.11499.3 3.99E-10 16/84 K.DHTPSQELALTQSVGGDSSADR[166.11].L "sp|Q86U44|MTA70_HUMAN,tr|H0YFV6|H0YFV6_HUMAN" 2 2280.0494 0.06 143162 11499 3 2280.046847 761.0237 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 4.22 2299.4 - 261388 - - - -1.1052 - 3.172 0.631 - 219 1 2 0 -0.0025 22 0 0 0 1.57E+05 2.68E+06 - - - 8.3111 0.9999 221125_WJC_METTL3_EV_vs_WT_F10.11505.11505.4 5.05E-07 18/102 R.EANFTVSSMHGDMPQK[136.11]ER[166.11].E "sp|P38919|IF4A3_HUMAN,tr|I3L3H2|I3L3H2_HUMAN" 2 2080.9425 1.32 143166 11505 4 2080.941046 521.2429 Eukaryotic initiation factor 4A-III OS=Homo sapiens OX=9606 GN=EIF4A3 PE=1 SV=4 5.45 2300.2 - 921297 - - - -0.7127 - 2.503 0.576 - 196.6 1 2 1 -0.0015 18 0 0 0 6.12E+06 4.62E+06 - - - 4.5534 0.9997 221125_WJC_METTL3_EV_vs_WT_F10.11520.11520.4 4.38E-06 14/108 K.TKYPTQSGKPPLLVSAPSK.S "sp|Q9GZR7|DDX24_HUMAN,tr|A0A087WXU8|A0A087WXU8_HUMAN,tr|F5GYL3|F5GYL3_HUMAN,tr|G3V529|G3V529_HUMAN" 4 1998.115 0.74 143177 11520 4 1998.117793 500.536 ATP-dependent RNA helicase DDX24 OS=Homo sapiens OX=9606 GN=DDX24 PE=1 SV=1 10 2302.1 - 290409 - - - 1.4093 - 2.985 0.432 - 148.6 1 2 1 0.0028 19 0 0 0 3.61E+06 4.88E+06 - - - 3.3553 0.8915 221125_WJC_METTL3_EV_vs_WT_F10.11522.11522.4 1.05 Jun-90 K.TDKTADGFAVPEPPKR.K sp|Q86XP3|DDX42_HUMAN 1 1727.8842 1.71 143179 11522 4 1727.885341 432.9783 ATP-dependent RNA helicase DDX42 OS=Homo sapiens OX=9606 GN=DDX42 PE=1 SV=1 5.79 2302.4 - 239531 - - - 0.632 - 1.352 0.168 - 26 1 2 1 0.0011 16 0 0 0 7.09E+06 4.14E+06 - - - 0.7942 0.9991 221125_WJC_METTL3_EV_vs_WT_F10.11523.11523.3 2.19E-10 Dec-92 R.QFTSSSSMKGSC[160.03]GIGGGIGGGSSR.L "sp|P02533|K1C14_HUMAN,sp|P08779|K1C16_HUMAN,tr|K7ENV3|K7ENV3_HUMAN" 3 2261.0165 1.89 143180 11523 3 2261.027757 754.6794 "Keratin, type I cytoskeletal 14 OS=Homo sapiens OX=9606 GN=KRT14 PE=1 SV=4" 9.51 2302.5 - 218965 - - - 4.988 - 2.675 0.645 - 111.1 1 2 1 0.0113 24 0 0 0 4.84E+06 2.56E+06 - - - 8.0133 0.9645 221125_WJC_METTL3_EV_vs_WT_F10.11541.11541.4 0.0122 Sep-84 K.NSFQPVNSLREEERR.E sp|P52756|RBM5_HUMAN 1 1859.9238 1.94 143194 11541 4 1859.92746 465.9882 RNA-binding protein 5 OS=Homo sapiens OX=9606 GN=RBM5 PE=1 SV=2 6.23 2304.9 - 188678 - - - 1.956 - 1.803 0.22 - 69.4 1 2 1 0.0036 15 0 0 0 4.36E+06 2.25E+06 - - - 1.3508 0.9995 221125_WJC_METTL3_EV_vs_WT_F10.11542.11542.3 0.0711 15/80 K.KPSAAPEAGASALPNPPALKK.E "sp|P39880|CUX1_HUMAN,tr|A0A2R8Y852|A0A2R8Y852_HUMAN,tr|A0A2R8YDI1|A0A2R8YDI1_HUMAN" 3 2014.1211 1.95 143195 11542 3 2014.128431 672.381 Homeobox protein cut-like 1 OS=Homo sapiens OX=9606 GN=CUX1 PE=1 SV=3 9.7 2305 - 174431 - - - 3.6274 - 2.664 0.4 - 205.2 1 2 0 0.0073 21 0 0 0 3.00E+06 1.54E+06 - - - 5.3467 0.9913 221125_WJC_METTL3_EV_vs_WT_F10.11543.11543.3 0.00857 Jul-72 K.TK[136.11]YPTQSGK[136.11]PPLLVSAPSK[136.11].S "sp|Q9GZR7|DDX24_HUMAN,tr|A0A087WXU8|A0A087WXU8_HUMAN,tr|F5GYL3|F5GYL3_HUMAN,tr|G3V529|G3V529_HUMAN" 4 2022.1576 0.8 143196 11543 3 2022.162281 675.0598 ATP-dependent RNA helicase DDX24 OS=Homo sapiens OX=9606 GN=DDX24 PE=1 SV=1 10 2305.2 - 163873 - - - 2.3262 - 1.739 0.321 - 43.6 1 2 1 0.0047 19 0 0 0 1.25E+06 1.55E+06 - - - 3.4769 0.9861 221125_WJC_METTL3_EV_vs_WT_F10.11545.11545.3 0.000105 Aug-72 K.TKYPTQSGKPPLLVSAPSK.S "sp|Q9GZR7|DDX24_HUMAN,tr|A0A087WXU8|A0A087WXU8_HUMAN,tr|F5GYL3|F5GYL3_HUMAN,tr|G3V529|G3V529_HUMAN" 4 1998.115 0.8 143198 11545 3 1998.124747 667.0456 ATP-dependent RNA helicase DDX24 OS=Homo sapiens OX=9606 GN=DDX24 PE=1 SV=1 10 2305.4 - 131650 - - - 4.8896 - 1.893 0.4 - 74.1 1 2 1 0.0098 19 0 0 0 1.25E+06 1.55E+06 - - - 4.5647 0.9998 221125_WJC_METTL3_EV_vs_WT_F10.11552.11552.4 0.00336 15/90 K.GAVLPQEISQVNQHHK.S "sp|Q8IZH2|XRN1_HUMAN,tr|H7C5E4|H7C5E4_HUMAN" 2 1783.9329 1.77 143203 11552 4 1783.937811 446.9905 5'-3' exoribonuclease 1 OS=Homo sapiens OX=9606 GN=XRN1 PE=1 SV=1 6.92 2306.4 - 302031 - - - 2.7361 - 2.7 0.439 - 166.7 1 2 0 0.0049 16 0 0 0 4.69E+06 2.65E+06 - - - 3.3956 0.8436 221125_WJC_METTL3_EV_vs_WT_F10.11555.11555.3 7.21E-09 20/80 F.ASSLVSGLNSSASEPAK[136.11]EPAK[136.11].K "sp|Q86U44|MTA70_HUMAN,tr|F5H6D8|F5H6D8_HUMAN,tr|H0YFV6|H0YFV6_HUMAN,tr|B4DTN4|B4DTN4_HUMAN" 4 2045.0612 0 143206 11555 3 2046.065881 682.6943 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 6.19 2306.8 - 435312 - - - 491.2895 - 3.548 0.571 - 439.5 1 1 1 1.0047 21 0 0 0 2.44E+05 8.60E+07 - - - 7.6639 0.9996 221125_WJC_METTL3_EV_vs_WT_F10.11557.11557.4 5.24E-07 13/108 K.TK[136.11]YPTQSGK[136.11]PPLLVSAPSK[136.11].S "sp|Q9GZR7|DDX24_HUMAN,tr|A0A087WXU8|A0A087WXU8_HUMAN,tr|F5GYL3|F5GYL3_HUMAN,tr|G3V529|G3V529_HUMAN" 4 2022.1576 0.76 143208 11557 4 2022.164597 506.5467 ATP-dependent RNA helicase DDX24 OS=Homo sapiens OX=9606 GN=DDX24 PE=1 SV=1 10 2307.1 - 364655 - - - 3.4715 - 2.345 0.537 - 105.5 1 2 1 0.007 19 0 0 0 3.61E+06 4.75E+06 - - - 4.1864 0.9992 221125_WJC_METTL3_EV_vs_WT_F10.11558.11558.4 0.000208 Nov-96 R.EGYAWAEDK[136.11]EHC[160.03]EEYGR[166.11].M sp|Q9Y3I0|RTCB_HUMAN 1 2145.8817 1.75 143209 11558 4 2145.889989 537.4777 RNA-splicing ligase RtcB homolog OS=Homo sapiens OX=9606 GN=RTCB PE=1 SV=1 4.41 2307.2 - 223250 - - - 3.8613 - 2.683 0.498 - 106.9 1 2 1 0.0083 17 0 0 0 2.15E+06 1.23E+06 - - - 3.901 1 221125_WJC_METTL3_EV_vs_WT_F10.11570.11570.4 2.13E-09 21/120 K.SLIGVEYKPVSATGAEDKDKK.K sp|P07814|SYEP_HUMAN 1 2234.1794 0.93 143219 11570 4 2234.18736 559.5521 Bifunctional glutamate\proline--tRNA ligase OS=Homo sapiens OX=9606 GN=EPRS1 PE=1 SV=5 5.94 2308.7 - 459243 - - - 3.5503 - 4.507 0.667 - 176.4 1 2 1 0.0079 21 0 0 0 7.90E+06 8.50E+06 - - - 5.5272 0.9234 221125_WJC_METTL3_EV_vs_WT_F10.11573.11573.4 0.0121 7/102 R.SQEIDDHQHEMSVLQNAH.Q sp|Q15643|TRIPB_HUMAN 1 2116.9232 - 143222 11573 4 2116.926645 530.2381 Thyroid receptor-interacting protein 11 OS=Homo sapiens OX=9606 GN=TRIP11 PE=1 SV=3 4.7 2309.1 - 297236 - - - 1.6132 - 1.679 0.334 - 30 1 1 0 0.0034 18 0 0 0 - - - - - 2.3097 0.9994 221125_WJC_METTL3_EV_vs_WT_F10.11576.11576.4 0.000365 Dec-96 R.EGYAWAEDKEHC[160.03]EEYGR.M sp|Q9Y3I0|RTCB_HUMAN 1 2127.8592 1.73 143225 11576 4 2127.866693 532.9721 RNA-splicing ligase RtcB homolog OS=Homo sapiens OX=9606 GN=RTCB PE=1 SV=1 4.41 2309.5 - 239445 - - - 3.5059 - 2.093 0.514 - 73.8 1 2 1 0.0075 17 0 0 0 2.18E+06 1.26E+06 - - - 3.9542 0.9999 221125_WJC_METTL3_EV_vs_WT_F10.11577.11577.3 0.000165 12/108 R.SSGATPVSGPPPPSASSTPAGQPTAVSR.L "sp|Q9C0H9|SRCN1_HUMAN,tr|A0A087X165|A0A087X165_HUMAN,tr|A0A087WVV7|A0A087WVV7_HUMAN,tr|A0A590UJ70|A0A590UJ70_HUMAN" 4 2547.2565 6.93 143226 11577 3 2547.260383 850.0928 SRC kinase signaling inhibitor 1 OS=Homo sapiens OX=9606 GN=SRCIN1 PE=1 SV=4 9.47 2309.6 - 105299 - - - 1.5209 - 1.839 0.473 - 79.9 1 2 0 0.0039 28 0 0 0 7.80E+05 1.13E+05 - - - 5.214 0.9998 221125_WJC_METTL3_EV_vs_WT_F10.11591.11591.4 5.66E-08 24/120 K.KPSAAPEAGASALPNPPALKK.E "sp|P39880|CUX1_HUMAN,tr|A0A2R8Y852|A0A2R8Y852_HUMAN,tr|A0A2R8YDI1|A0A2R8YDI1_HUMAN" 3 2014.1211 1.76 143238 11591 4 2014.129306 504.5376 Homeobox protein cut-like 1 OS=Homo sapiens OX=9606 GN=CUX1 PE=1 SV=3 9.7 2311.5 - 731057 - - - 4.0618 - 2.841 0.507 - 320.3 1 2 0 0.0082 21 0 0 0 3.56E+07 2.02E+07 - - - 3.9819 1 221125_WJC_METTL3_EV_vs_WT_F10.11595.11595.3 2.07E-11 15/96 K.VNFSEEGETEEDDQDSSHSSVTTVK[136.11].A "sp|Q5JTV8|TOIP1_HUMAN,tr|H0YD16|H0YD16_HUMAN,tr|J3KN66|J3KN66_HUMAN,tr|A0A0A0MSK5|A0A0A0MSK5_HUMAN" 4 2763.1722 1.29 143242 11595 3 2763.174523 922.0647 Torsin-1A-interacting protein 1 OS=Homo sapiens OX=9606 GN=TOR1AIP1 PE=1 SV=2 3.89 2312 - 178993 - - - 0.8273 - 3.274 0.782 - 141.4 1 2 0 0.0023 25 0 0 0 2.65E+06 2.05E+06 - - - 9.9865 1 221125_WJC_METTL3_EV_vs_WT_F10.11603.11603.4 1.03E-09 21/102 R.SPSKPLPEVTDEYKNDVK.N "sp|P05455|LA_HUMAN,tr|E9PGX9|E9PGX9_HUMAN,tr|E9PFL9|E9PFL9_HUMAN,tr|E7ERC4|E7ERC4_HUMAN" 4 2045.0317 0.96 143248 11603 4 2045.041105 512.2652 Lupus La protein OS=Homo sapiens OX=9606 GN=SSB PE=1 SV=2 4.78 2313.1 - 773287 - - - 4.5985 - 4.16 0.622 - 375.7 1 2 1 0.0094 18 0 0 0 5.28E+07 5.51E+07 - - - 5.1256 1 221125_WJC_METTL3_EV_vs_WT_F10.11606.11606.3 2.45E-11 18/96 K.VNFSEEGETEEDDQDSSHSSVTTVK.A "sp|Q5JTV8|TOIP1_HUMAN,tr|H0YD16|H0YD16_HUMAN,tr|J3KN66|J3KN66_HUMAN,tr|A0A0A0MSK5|A0A0A0MSK5_HUMAN" 4 2755.158 1.29 143251 11606 3 2755.166403 919.3933 Torsin-1A-interacting protein 1 OS=Homo sapiens OX=9606 GN=TOR1AIP1 PE=1 SV=2 3.89 2313.4 - 247652 - - - 3.0365 - 4.425 0.772 - 265.5 1 2 0 0.0084 25 0 0 0 2.65E+06 2.05E+06 - - - 10.5664 0.9997 221125_WJC_METTL3_EV_vs_WT_F10.11615.11615.4 2.65E-08 17/102 R.SPSK[136.11]PLPEVTDEYK[136.11]NDVK[136.11].N "sp|P05455|LA_HUMAN,tr|E9PGX9|E9PGX9_HUMAN,tr|E9PFL9|E9PFL9_HUMAN,tr|E7ERC4|E7ERC4_HUMAN" 4 2069.0743 1.02 143258 11615 4 2069.081644 518.2759 Lupus La protein OS=Homo sapiens OX=9606 GN=SSB PE=1 SV=2 4.78 2314.6 - 1.27E+06 - - - 3.5489 - 3.665 0.568 - 189 1 2 1 0.0073 18 0 0 0 5.25E+07 5.16E+07 - - - 4.6128 0.9998 221125_WJC_METTL3_EV_vs_WT_F10.11617.11617.4 0.00011 Oct-96 R.RDGTGHYLC[160.03]NAC[160.03]GLYSK.M sp|Q92908|GATA6_HUMAN 1 1970.8727 0.49 143260 11617 4 1970.878791 493.7255 Transcription factor GATA-6 OS=Homo sapiens OX=9606 GN=GATA6 PE=1 SV=2 8.04 2314.9 - 91563.4 - - - 3.0829 - 1.85 0.489 - 66 1 2 0 0.0061 17 0 0 0 6.52E+05 1.33E+06 - - - 3.6942 1 221125_WJC_METTL3_EV_vs_WT_F10.11630.11630.3 1.73E-09 30/68 R.SPSK[136.11]PLPEVTDEYK[136.11]NDVK[136.11].N "sp|P05455|LA_HUMAN,tr|E9PGX9|E9PGX9_HUMAN,tr|E9PFL9|E9PFL9_HUMAN,tr|E7ERC4|E7ERC4_HUMAN" 4 2069.0743 0.001 143269 11630 3 2069.079445 690.6987 Lupus La protein OS=Homo sapiens OX=9606 GN=SSB PE=1 SV=2 4.78 2316.7 - 889987 - - - 2.4861 - 5.096 0.662 - 1340.7 1 2 1 0.0051 18 0 0 0 0.00E+00 2.39E+07 - - - 9.9742 0.9921 221125_WJC_METTL3_EV_vs_WT_F10.11631.11631.3 0.0189 Aug-36 R.TKYETELNLR.M sp|P02533|K1C14_HUMAN 1 1265.6616 999 143270 11631 3 1265.664403 422.8945 "Keratin, type I cytoskeletal 14 OS=Homo sapiens OX=9606 GN=KRT14 PE=1 SV=4" 5.81 2316.8 - 279929 - - - 2.2415 - 1.853 0.284 - 151.2 1 2 1 0.0028 10 0 0 0 4.99E+06 0.00E+00 - - - 3.5069 0.9999 221125_WJC_METTL3_EV_vs_WT_F10.11638.11638.4 5.74E-07 Dec-72 K.AFDTDIHALRPHR.G sp|P42357|HUTH_HUMAN 1 1547.7957 21.64 143275 11638 4 1547.798414 387.9562 Histidine ammonia-lyase OS=Homo sapiens OX=9606 GN=HAL PE=1 SV=1 6.96 2317.8 - 238160 - - - 1.7476 - 2.542 0.489 - 103.8 1 2 0 0.0027 13 0 0 0 3.01E+06 1.39E+05 - - - 3.8274 0.9998 221125_WJC_METTL3_EV_vs_WT_F10.11647.11647.3 2.37E-05 Oct-80 K.GAQVNAVNQNGC[160.03]TPLHYAASK.N "sp|O75832|PSD10_HUMAN,tr|B1AJY7|B1AJY7_HUMAN" 2 2199.0491 1.23 143282 11647 3 2199.057613 734.0236 26S proteasome non-ATPase regulatory subunit 10 OS=Homo sapiens OX=9606 GN=PSMD10 PE=1 SV=1 8.21 2319 - 159732 - - - 3.8712 - 2.345 0.569 - 93.5 1 2 0 0.0085 21 0 0 0 4.37E+06 3.55E+06 - - - 6.9247 0.9993 221125_WJC_METTL3_EV_vs_WT_F10.11648.11648.3 0.000682 Dec-48 R.K[136.11]TEELEEESFPER[166.11].S "sp|Q9Y2W1|TR150_HUMAN,tr|A0A3B3ITZ9|A0A3B3ITZ9_HUMAN" 2 1639.7696 2.88 143283 11648 3 1639.77537 547.5971 Thyroid hormone receptor-associated protein 3 OS=Homo sapiens OX=9606 GN=THRAP3 PE=1 SV=2 4.21 2319.1 - 155391 - - - 3.509 - 2.512 0.356 - 256.4 1 2 0 0.0058 13 0 0 0 2.37E+07 8.23E+06 - - - 5.0048 0.9999 221125_WJC_METTL3_EV_vs_WT_F10.11650.11650.3 3.45E-05 10/112 K.AQGPAASAEEPKPVEAPAANSDQTVTVKE.- sp|P80723|BASP1_HUMAN 1 2891.4149 1.66 143285 11650 3 2891.420849 964.8122 Brain acid soluble protein 1 OS=Homo sapiens OX=9606 GN=BASP1 PE=1 SV=2 4.43 2319.4 - 123399 - - - 2.071 - 2.432 0.504 - 73.2 1 2 0 0.006 29 0 0 0 1.16E+06 6.96E+05 - - - 6.2021 1 221125_WJC_METTL3_EV_vs_WT_F10.11655.11655.3 1.14E-13 24/76 R.LSDAGQYLC[160.03]QAGDDSNSNKK.N sp|P01833|PIGR_HUMAN 1 2169.9597 999 143288 11655 3 2169.975909 724.3272 Polymeric immunoglobulin receptor OS=Homo sapiens OX=9606 GN=PIGR PE=1 SV=4 4.43 2320.1 - 542975 - - - 7.4808 - 4.636 0.695 - 806 1 2 0 0.0162 20 0 0 0 1.14E+07 0.00E+00 - - - 10.0052 1 221125_WJC_METTL3_EV_vs_WT_F10.11656.11656.4 3.26E-14 16/114 R.YGAQC[160.03]TSAHSQEELAEWQKR.Y "sp|P42694|HELZ_HUMAN,tr|J3QS41|J3QS41_HUMAN,tr|A0A075B6R3|A0A075B6R3_HUMAN" 3 2378.071 1.81 143289 11656 4 2378.08151 595.525 Probable helicase with zinc finger domain OS=Homo sapiens OX=9606 GN=HELZ PE=1 SV=2 5.5 2320.2 - 286850 - - - 4.4376 - 3.609 0.721 - 230.2 1 2 0 0.0106 20 0 0 0 6.28E+06 3.48E+06 - - - 5.9277 1 221125_WJC_METTL3_EV_vs_WT_F10.11657.11657.4 2.11E-12 20/108 R.GR[166.11]AQVQEFC[160.03]DYGTK[136.11]EEC[160.03]MK[136.11].A "sp|Q86U44|MTA70_HUMAN,tr|H0YFV6|H0YFV6_HUMAN" 2 2361.0398 0.01 143290 11657 4 2361.046894 591.2672 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 4.87 2320.4 - 843468 - - - 3.0016 - 3.864 0.678 - 305.5 1 2 2 0.0071 19 0 0 0 4.16E+05 4.71E+07 - - - 5.5826 1 221125_WJC_METTL3_EV_vs_WT_F10.11659.11659.3 7.45E-06 19/72 R.GR[166.11]AQVQEFC[160.03]DYGTK[136.11]EEC[160.03]MK[136.11].A "sp|Q86U44|MTA70_HUMAN,tr|H0YFV6|H0YFV6_HUMAN" 2 2361.0398 0.001 143292 11659 3 2362.045234 788.0205 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 4.87 2320.6 - 264622 - - - 425.8408 - 4.079 0.67 - 427.6 1 2 2 1.0054 19 0 0 0 0.00E+00 1.41E+07 - - - 9.1852 0.9972 221125_WJC_METTL3_EV_vs_WT_F10.11660.11660.4 0.000147 13/156 K.ADGLGGKGEPGGGPGELAPVGPDEKEK.G sp|P55316|FOXG1_HUMAN 1 2517.2347 1.8 143293 11660 4 2517.24327 630.316 Forkhead box protein G1 OS=Homo sapiens OX=9606 GN=FOXG1 PE=1 SV=2 4.36 2320.7 - 232760 - - - 3.4002 - 2.675 0.387 - 76.1 1 2 2 0.0086 27 0 0 0 1.31E+07 7.28E+06 - - - 2.8999 0.946 221125_WJC_METTL3_EV_vs_WT_F10.11662.11662.3 0.000239 Aug-76 L.KIVSSSDVGHDEYSTQSLVK.K "sp|Q01082|SPTB2_HUMAN,tr|A0A087WUZ3|A0A087WUZ3_HUMAN" 2 2178.0804 0.92 143295 11662 3 2178.088435 727.0341 "Spectrin beta chain, non-erythrocytic 1 OS=Homo sapiens OX=9606 GN=SPTBN1 PE=1 SV=2" 5.38 2321 - 142560 - - - 3.6697 - 1.897 0.47 - 51.6 1 1 0 0.008 20 0 0 0 9.39E+05 1.02E+06 - - - 5.3311 0.9873 221125_WJC_METTL3_EV_vs_WT_F10.11663.11663.3 0.00806 7/112 K.AQGPAASAEEPK[136.11]PVEAPAANSDQTVTVK[136.11]E.- sp|P80723|BASP1_HUMAN 1 2907.4433 1.66 143296 11663 3 2907.455096 970.155 Brain acid soluble protein 1 OS=Homo sapiens OX=9606 GN=BASP1 PE=1 SV=2 4.43 2321.1 - 63393.7 - - - 4.0706 - 1.374 0.336 - 21.7 1 2 0 0.0118 29 0 0 0 1.16E+06 6.96E+05 - - - 3.0138 0.9996 221125_WJC_METTL3_EV_vs_WT_F10.11668.11668.4 0.000186 16/156 K.ADGLGGK[136.11]GEPGGGPGELAPVGPDEK[136.11]EK[136.11].G sp|P55316|FOXG1_HUMAN 1 2541.2773 1.78 143298 11668 4 2541.284542 636.3266 Forkhead box protein G1 OS=Homo sapiens OX=9606 GN=FOXG1 PE=1 SV=2 4.36 2321.8 - 291290 - - - 2.8454 - 3.38 0.483 - 119.9 1 2 2 0.0072 27 0 0 0 1.29E+07 7.28E+06 - - - 3.8091 0.9952 221125_WJC_METTL3_EV_vs_WT_F10.11669.11669.4 0.0109 8/108 R.GLLQDDAHPTLVTYADHSK[136.11].L "sp|Q86U44|MTA70_HUMAN,tr|F5H6D8|F5H6D8_HUMAN,tr|H0YFV6|H0YFV6_HUMAN,tr|B4DTN4|B4DTN4_HUMAN" 4 2088.0367 0.02 143299 11669 4 2088.041761 523.0165 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 5.13 2321.9 - 198348 - - - 2.408 - 2.082 0.257 - 56.1 1 2 0 0.005 19 0 0 0 5.07E+05 3.22E+07 - - - 1.7096 0.9992 221125_WJC_METTL3_EV_vs_WT_F10.11671.11671.3 9.62E-09 16/108 R.AAPRPAPVAQPPAAAPPSAVGSSAAAPR.Q "sp|Q5T1J5|CHCH9_HUMAN,sp|Q9Y6H1|CHCH2_HUMAN" 2 2532.3561 8.82 143301 11671 3 2532.369713 845.126 "Putative coiled-coil-helix-coiled-coil-helix domain-containing protein CHCHD2P9, mitochondrial OS=Homo sapiens OX=9606 GN=CHCHD2P9 PE=5 SV=1" 12 2322.2 - 168711 - - - 5.374 - 2.952 0.464 - 162.7 1 2 0 0.0136 28 0 0 0 1.13E+06 1.28E+05 - - - 6.1998 1 221125_WJC_METTL3_EV_vs_WT_F10.11675.11675.3 1.32E-10 19/84 R.ISC[160.03]GGGINVDVNQHPDGGPGGK.A sp|Q96F45|ZN503_HUMAN 1 2133.9862 2.01 143303 11675 3 2133.991634 712.336 Zinc finger protein 503 OS=Homo sapiens OX=9606 GN=ZNF503 PE=1 SV=1 5.21 2322.8 - 323091 - - - 2.5628 - 3.514 0.519 - 332.6 1 2 0 0.0055 22 0 0 0 6.35E+06 3.15E+06 - - - 7.3044 0.9998 221125_WJC_METTL3_EV_vs_WT_F10.11676.11676.3 0.149 17/48 R.KTEELEEESFPER.S "sp|Q9Y2W1|TR150_HUMAN,tr|A0A3B3ITZ9|A0A3B3ITZ9_HUMAN" 2 1621.7471 2.88 143304 11676 3 1621.752472 541.5897 Thyroid hormone receptor-associated protein 3 OS=Homo sapiens OX=9606 GN=THRAP3 PE=1 SV=2 4.21 2322.9 - 1.01E+06 - - - 3.2841 - 2.82 0.432 - 509.3 1 2 0 0.0053 13 0 0 0 2.37E+07 8.23E+06 - - - 6.1658 0.9999 221125_WJC_METTL3_EV_vs_WT_F10.11677.11677.3 2.76E-06 Dec-84 R.ISC[160.03]GGGINVDVNQHPDGGPGGK[136.11].A sp|Q96F45|ZN503_HUMAN 1 2142.0004 1.97 143305 11677 3 2142.007383 715.0074 Zinc finger protein 503 OS=Homo sapiens OX=9606 GN=ZNF503 PE=1 SV=1 5.21 2323 - 211109 - - - 3.2764 - 2.219 0.544 - 108.6 1 2 0 0.007 22 0 0 0 5.17E+06 2.62E+06 - - - 6.4928 0.9984 221125_WJC_METTL3_EV_vs_WT_F10.11678.11678.4 2.70E-05 12/120 K.KPYQLIAQDNETEKPIDSETK.M "sp|P43003|EAA1_HUMAN,tr|A0A087WT87|A0A087WT87_HUMAN,tr|A0A7P0TAG7|A0A7P0TAG7_HUMAN,tr|A0A087X0U3|A0A087X0U3_HUMAN,tr|A0A7P0Z4R4|A0A7P0Z4R4_HUMAN" 5 2446.2227 2.31 143306 11678 4 2446.235033 612.563 Excitatory amino acid transporter 1 OS=Homo sapiens OX=9606 GN=SLC1A3 PE=1 SV=1 4.51 2323.1 - 172608 - - - 5.0212 - 2.289 0.415 - 79.2 1 2 0 0.0123 21 0 0 0 2.42E+06 1.05E+06 - - - 3.1086 0.9996 221125_WJC_METTL3_EV_vs_WT_F10.11681.11681.4 0.000248 Sep-72 K.KIHEEFSEHALLR.K "sp|Q9Y2L1|RRP44_HUMAN,tr|G3V1J5|G3V1J5_HUMAN" 2 1607.842 1.46 143309 11681 4 1607.844942 402.9678 Exosome complex exonuclease RRP44 OS=Homo sapiens OX=9606 GN=DIS3 PE=1 SV=2 6.02 2323.5 - 126196 - - - 1.836 - 1.787 0.365 - 84.7 1 2 0 0.003 13 0 0 0 3.33E+06 2.29E+06 - - - 2.6174 0.8465 221125_WJC_METTL3_EV_vs_WT_F10.11688.11688.4 0.0454 Sep-84 K.K[136.11]FDEK[136.11]ENVSNC[160.03]IQLK[136.11].T sp|Q9ULC4|MCTS1_HUMAN 1 1874.9622 0.36 143314 11688 4 1874.967333 469.7478 Malignant T-cell-amplified sequence 1 OS=Homo sapiens OX=9606 GN=MCTS1 PE=1 SV=1 6.17 2324.4 - 259667 - - - 2.7115 - 1.619 0.181 - 60 1 2 1 0.0051 15 0 0 0 2.06E+06 5.65E+06 - - - 0.9724 0.9996 221125_WJC_METTL3_EV_vs_WT_F10.11691.11691.3 3.45E-08 13/56 K.KFDEKENVSNC[160.03]IQLK.T sp|Q9ULC4|MCTS1_HUMAN 1 1850.9196 0.48 143315 11691 3 1850.924736 617.9805 Malignant T-cell-amplified sequence 1 OS=Homo sapiens OX=9606 GN=MCTS1 PE=1 SV=1 6.17 2324.9 - 273602 - - - 2.7484 - 2.526 0.519 - 166.2 1 2 1 0.0051 15 0 0 0 3.69E+06 7.73E+06 - - - 6.7429 0.9897 221125_WJC_METTL3_EV_vs_WT_F10.11695.11695.4 0.00061 Dec-96 L.LQDDAHPTLVTYADHSK[136.11].L "sp|Q86U44|MTA70_HUMAN,tr|F5H6D8|F5H6D8_HUMAN,tr|H0YFV6|H0YFV6_HUMAN,tr|B4DTN4|B4DTN4_HUMAN" 4 1917.9312 0.23 143317 11695 4 1917.933755 480.4901 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 5.13 2325.6 - 248168 - - - 1.329 - 1.869 0.445 - 101.3 1 1 0 0.0025 17 0 0 0 1.13E+06 4.88E+06 - - - 3.3157 0.9997 221125_WJC_METTL3_EV_vs_WT_F10.11701.11701.2 3.85E-06 24-Sep R.KTEELEEESFPER.S "sp|Q9Y2W1|TR150_HUMAN,tr|A0A3B3ITZ9|A0A3B3ITZ9_HUMAN" 2 1621.7471 13.39 143323 11701 2 1621.751209 811.8808 Thyroid hormone receptor-associated protein 3 OS=Homo sapiens OX=9606 GN=THRAP3 PE=1 SV=2 4.21 2326.4 - 83847.4 - - - 2.5053 - 2.135 0.602 - 258.6 1 2 0 0.0041 13 0 0 0 2.36E+06 1.76E+05 - - - 5.4327 0.9999 221125_WJC_METTL3_EV_vs_WT_F10.11703.11703.4 6.62E-08 25/120 K.K[136.11]PSAAPEAGASALPNPPALK[136.11]K[136.11].E "sp|P39880|CUX1_HUMAN,tr|A0A2R8Y852|A0A2R8Y852_HUMAN,tr|A0A2R8YDI1|A0A2R8YDI1_HUMAN" 3 2038.1637 1.75 143324 11703 4 2038.170434 510.5482 Homeobox protein cut-like 1 OS=Homo sapiens OX=9606 GN=CUX1 PE=1 SV=3 9.7 2326.6 - 789558 - - - 3.2917 - 2.93 0.563 - 430.4 1 2 0 0.0067 21 0 0 0 3.72E+07 2.12E+07 - - - 4.4799 0.9324 221125_WJC_METTL3_EV_vs_WT_F10.11706.11706.3 1.14 Sep-72 R.GLLQDDAHPTLVTYADHSK[136.11].L "sp|Q86U44|MTA70_HUMAN,tr|F5H6D8|F5H6D8_HUMAN,tr|H0YFV6|H0YFV6_HUMAN,tr|B4DTN4|B4DTN4_HUMAN" 4 2088.0367 0.01 143326 11706 3 2088.042804 697.0195 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 5.13 2327 - 396074 - - - 2.9075 - 1.691 0.141 - 87.9 1 2 0 0.0061 19 0 0 0 3.13E+04 4.61E+06 - - - 1.4009 1 221125_WJC_METTL3_EV_vs_WT_F10.11708.11708.3 4.02E-10 23/76 K.HLEQQQGQLEVPEQQVGQPK.N sp|P07476|INVO_HUMAN 1 2299.1557 999 143328 11708 3 2299.168234 767.3925 Involucrin OS=Homo sapiens OX=9606 GN=IVL PE=1 SV=2 4.75 2327.2 - 255320 - - - 5.4633 - 4.427 0.652 - 676.9 1 2 0 0.0126 20 0 0 0 2.76E+06 0.00E+00 - - - 9.4149 0.9967 221125_WJC_METTL3_EV_vs_WT_F10.11710.11710.2 0.000284 14-Jul K.VIPELNGK[136.11].L "sp|P04406|G3P_HUMAN,tr|E7EUT5|E7EUT5_HUMAN" 2 876.516 1.1 143330 11710 2 876.51919 439.2653 Glyceraldehyde-3-phosphate dehydrogenase OS=Homo sapiens OX=9606 GN=GAPDH PE=1 SV=3 5.97 2327.5 - 132209 - - - 3.6189 - 1.424 0.406 - 132.2 1 2 0 0.0032 8 0 0 0 2.68E+06 2.42E+06 - - - 3.1048 1 221125_WJC_METTL3_EV_vs_WT_F10.11716.11716.3 3.23E-11 29/80 R.EQAGGDATENFEDVGHSTDAR.E sp|P00167|CYB5_HUMAN 1 2204.9206 1.97 143334 11716 3 2204.92713 735.9808 Cytochrome b5 OS=Homo sapiens OX=9606 GN=CYB5A PE=1 SV=2 4.01 2328.3 - 1.01E+06 - - - 2.9402 - 4.317 0.736 - 880 1 2 0 0.0065 21 0 0 0 1.55E+08 7.87E+07 - - - 10.2503 0.9999 221125_WJC_METTL3_EV_vs_WT_F10.11717.11717.3 2.14E-09 19/80 K.K[136.11]PSAAPEAGASALPNPPALK[136.11]K[136.11].E "sp|P39880|CUX1_HUMAN,tr|A0A2R8Y852|A0A2R8Y852_HUMAN,tr|A0A2R8YDI1|A0A2R8YDI1_HUMAN" 3 2038.1637 1.46 143335 11717 3 2038.16763 680.3952 Homeobox protein cut-like 1 OS=Homo sapiens OX=9606 GN=CUX1 PE=1 SV=3 9.7 2328.4 - 207036 - - - 1.9159 - 3.056 0.403 - 337.5 1 2 0 0.0039 21 0 0 0 1.29E+07 8.87E+06 - - - 5.7102 1 221125_WJC_METTL3_EV_vs_WT_F10.11722.11722.3 3.99E-06 Oct-80 K.C[160.03]DITTAPGPPDQC[160.03]K[136.11]PPQVTC[160.03]R[166.11].S sp|Q9Y2H6|FND3A_HUMAN 1 2415.11 0.75 143340 11722 3 2415.111568 806.0439 Fibronectin type-III domain-containing protein 3A OS=Homo sapiens OX=9606 GN=FNDC3A PE=1 SV=4 5.94 2329 - 107052 - - - 0.6468 - 2.107 0.584 - 94.7 1 2 0 0.0016 21 0 0 0 1.94E+06 2.60E+06 - - - 6.8373 0.9993 221125_WJC_METTL3_EV_vs_WT_F10.11725.11725.3 0.00419 Jul-36 R.K[136.11]QDSGHLDLR[166.11].N "sp|Q86U44|MTA70_HUMAN,tr|B4E349|B4E349_HUMAN,tr|F5H6D8|F5H6D8_HUMAN,tr|B4DTN4|B4DTN4_HUMAN" 4 1185.6221 0.01 143342 11725 3 1185.625093 396.2146 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 6.75 2329.4 - 196609 - - - 2.5202 - 1.692 0.386 - 73.7 1 2 0 0.003 10 0 0 0 1.45E+05 1.12E+07 - - - 4.3786 0.984 221125_WJC_METTL3_EV_vs_WT_F10.11730.11730.4 0.0214 Nov-96 K.EDGSKYETIHLTEEPTK.L "sp|Q9H2P0|ADNP_HUMAN,tr|A0A2R8Y6X0|A0A2R8Y6X0_HUMAN,tr|A0A669KBJ7|A0A669KBJ7_HUMAN" 3 1975.9375 0.4 143346 11730 4 1975.940809 494.9916 Activity-dependent neuroprotector homeobox protein OS=Homo sapiens OX=9606 GN=ADNP PE=1 SV=1 4.57 2330 - 195187 - - - 1.6919 - 1.982 0.245 - 92.7 1 2 1 0.0033 17 0 0 0 3.51E+06 8.87E+06 - - - 1.5951 1 221125_WJC_METTL3_EV_vs_WT_F10.11734.11734.2 1.82E-08 16/38 K.ASESSKPWPDATYGTGSASR.A "sp|Q9Y2W1|TR150_HUMAN,tr|A0A3B3ITZ9|A0A3B3ITZ9_HUMAN" 2 2053.9341 3.15 143350 11734 2 2053.936364 1027.9743 Thyroid hormone receptor-associated protein 3 OS=Homo sapiens OX=9606 GN=THRAP3 PE=1 SV=2 6.11 2330.5 - 95177.6 - - - 1.0964 - 2.852 0.569 - 337.9 1 2 0 0.0023 20 0 0 0 6.72E+08 2.13E+08 - - - 5.8195 0.9992 221125_WJC_METTL3_EV_vs_WT_F10.11735.11735.2 4.35E-08 Oct-38 K.ASESSK[136.11]PWPDATYGTGSASR[166.11].A "sp|Q9Y2W1|TR150_HUMAN,tr|A0A3B3ITZ9|A0A3B3ITZ9_HUMAN" 2 2071.9566 3.15 143351 11735 2 2071.964618 1036.9856 Thyroid hormone receptor-associated protein 3 OS=Homo sapiens OX=9606 GN=THRAP3 PE=1 SV=2 6.11 2330.7 - 61697.1 - - - 3.8785 - 1.977 0.632 - 136.2 1 2 0 0.008 20 0 0 0 6.72E+08 2.13E+08 - - - 5.3821 1 221125_WJC_METTL3_EV_vs_WT_F10.11737.11737.3 8.26E-11 32/76 K.ASESSKPWPDATYGTGSASR.A "sp|Q9Y2W1|TR150_HUMAN,tr|A0A3B3ITZ9|A0A3B3ITZ9_HUMAN" 2 2053.9341 2.69 143352 11737 3 2053.939794 685.652 Thyroid hormone receptor-associated protein 3 OS=Homo sapiens OX=9606 GN=THRAP3 PE=1 SV=2 6.11 2330.9 - 3.17E+07 - - - 2.7664 - 4.265 0.553 - 1010.6 1 2 0 0.0057 20 0 0 0 2.11E+10 7.86E+09 - - - 8.2226 0.9509 221125_WJC_METTL3_EV_vs_WT_F10.11742.11742.4 0.0155 9/114 K.ASESSKPWPDATYGTGSASR.A "sp|Q9Y2W1|TR150_HUMAN,tr|A0A3B3ITZ9|A0A3B3ITZ9_HUMAN" 2 2053.9341 4.41 143356 11742 4 2053.943077 514.4908 Thyroid hormone receptor-associated protein 3 OS=Homo sapiens OX=9606 GN=THRAP3 PE=1 SV=2 6.11 2331.6 - 291323 - - - 4.3648 - 1.882 0.22 - 62.6 1 2 0 0.009 20 0 0 0 5.52E+07 1.25E+07 - - - 1.3498 0.9848 221125_WJC_METTL3_EV_vs_WT_F10.11745.11745.3 0.059 Aug-64 K.EDGSKYETIHLTEEPTK.L "sp|Q9H2P0|ADNP_HUMAN,tr|A0A2R8Y6X0|A0A2R8Y6X0_HUMAN,tr|A0A669KBJ7|A0A669KBJ7_HUMAN" 3 1975.9375 1.4 143359 11745 3 1975.935155 659.6531 Activity-dependent neuroprotector homeobox protein OS=Homo sapiens OX=9606 GN=ADNP PE=1 SV=1 4.57 2331.9 - 161142 - - - -1.1696 - 1.913 0.212 - 93.4 1 2 1 -0.0023 17 0 0 0 2.03E+06 1.45E+06 - - - 2.5417 1 221125_WJC_METTL3_EV_vs_WT_F10.11750.11750.3 5.99E-10 31/76 K.ASESSK[136.11]PWPDATYGTGSASR[166.11].A "sp|Q9Y2W1|TR150_HUMAN,tr|A0A3B3ITZ9|A0A3B3ITZ9_HUMAN" 2 2071.9566 2.69 143363 11750 3 2071.956636 691.6595 Thyroid hormone receptor-associated protein 3 OS=Homo sapiens OX=9606 GN=THRAP3 PE=1 SV=2 6.11 2332.6 - 4.88E+07 - - - 0.0261 - 4.722 0.669 - 918.5 1 2 0 0.0001 20 0 0 0 2.11E+10 7.86E+09 - - - 9.7644 0.9998 221125_WJC_METTL3_EV_vs_WT_F10.11755.11755.4 0.000735 19/108 K.QAQEKFELSENC[160.03]SERPGLR.G "sp|Q14203|DCTN1_HUMAN,tr|A0A804CDA6|A0A804CDA6_HUMAN,tr|E7EX90|E7EX90_HUMAN,tr|A0A7P0Z4C3|A0A7P0Z4C3_HUMAN,tr|Q6AWB1|Q6AWB1_HUMAN" 5 2277.0808 3.66 143366 11755 4 2277.078472 570.2775 Dynactin subunit 1 OS=Homo sapiens OX=9606 GN=DCTN1 PE=1 SV=3 4.95 2333.2 - 806887 - - - -1.0197 - 3.369 0.451 - 284.5 1 2 1 -0.0023 19 0 0 0 2.78E+07 7.58E+06 - - - 3.5617 0.9998 221125_WJC_METTL3_EV_vs_WT_F10.11759.11759.3 1.48E-06 24/76 K.QSAQLTALAAQQQAAGK[136.11]EEK[136.11].S sp|Q96A49|SYAP1_HUMAN 1 2086.0989 1.39 143368 11759 3 2086.092793 696.3736 Synapse-associated protein 1 OS=Homo sapiens OX=9606 GN=SYAP1 PE=1 SV=1 6.14 2333.7 - 1.16E+06 - - - -2.9495 - 4.394 0.548 - 966.6 1 2 1 -0.0062 20 0 0 0 5.98E+07 4.29E+07 - - - 8.2391 0.9823 221125_WJC_METTL3_EV_vs_WT_F10.11766.11766.3 0.000188 16/60 K.LK[136.11]GEATVSFDDPPSAK[136.11].A "sp|P35637|FUS_HUMAN,tr|H3BPE7|H3BPE7_HUMAN" 2 1676.8592 0.75 143372 11766 3 1676.85416 559.9603 RNA-binding protein FUS OS=Homo sapiens OX=9606 GN=FUS PE=1 SV=1 4.56 2334.6 - 453757 - - - -3.0152 - 2.392 0.225 - 273.3 1 2 1 -0.0051 16 0 0 0 1.68E+07 2.25E+07 - - - 3.2849 0.9997 221125_WJC_METTL3_EV_vs_WT_F10.11800.11800.4 7.97E-06 19/90 K.HPELADKNVPNLHVMK.A "sp|Q9NQ39|RS10L_HUMAN,sp|P46783|RS10_HUMAN,tr|A0A2R8Y6L3|A0A2R8Y6L3_HUMAN,tr|F6U211|F6U211_HUMAN,tr|A0A1W2PQS6|A0A1W2PQS6_HUMAN,tr|A0A2R8YFH6|A0A2R8YFH6_HUMAN,tr|A0A2R8Y7H1|A0A2R8Y7H1_HUMAN,tr|S4R435|S4R435_HUMAN" 8 1840.9618 1.18 143390 11800 4 1840.957381 461.2477 Putative 40S ribosomal protein S10-like OS=Homo sapiens OX=9606 GN=RPS10P5 PE=5 SV=1 6.92 2338.9 - 780108 - - - -2.3939 - 3.228 0.482 - 328.5 1 2 1 -0.0044 16 0 0 0 2.17E+08 1.84E+08 - - - 3.8329 1 221125_WJC_METTL3_EV_vs_WT_F10.11813.11813.3 1.19E-11 23/84 R.RLLEGEDAHLSSQQASGQSYSS.R sp|P08779|K1C16_HUMAN 1 2349.0833 999 143396 11813 3 2349.076651 784.035 "Keratin, type I cytoskeletal 16 OS=Homo sapiens OX=9606 GN=KRT16 PE=1 SV=4" 4.65 2340.7 - 1.60E+06 - - - -2.8288 - 4.278 0.684 - 694.4 1 1 0 -0.0066 22 0 0 0 6.08E+07 0.00E+00 - - - 9.6101 0.9955 221125_WJC_METTL3_EV_vs_WT_F10.11825.11825.3 0.00449 Nov-60 K.HPELADK[136.11]NVPNLHVMK[136.11].A "sp|Q9NQ39|RS10L_HUMAN,sp|P46783|RS10_HUMAN,tr|A0A2R8Y6L3|A0A2R8Y6L3_HUMAN,tr|F6U211|F6U211_HUMAN,tr|A0A1W2PQS6|A0A1W2PQS6_HUMAN,tr|A0A2R8YFH6|A0A2R8YFH6_HUMAN,tr|A0A2R8Y7H1|A0A2R8Y7H1_HUMAN,tr|S4R435|S4R435_HUMAN" 8 1856.9902 1.22 143402 11825 3 1856.987481 620.004 Putative 40S ribosomal protein S10-like OS=Homo sapiens OX=9606 GN=RPS10P5 PE=5 SV=1 6.92 2342.1 - 775577 - - - -1.4577 - 1.94 0.292 - 110.2 1 2 1 -0.0027 16 0 0 0 3.10E+07 2.53E+07 - - - 3.4951 0.9972 221125_WJC_METTL3_EV_vs_WT_F10.11831.11831.4 1.05E-06 32/120 R.PRPDPSPEIEGDLQPATHGSR.F sp|P51970|NDUA8_HUMAN 1 2255.0931 1.57 143406 11831 4 2255.088547 564.7805 NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 8 OS=Homo sapiens OX=9606 GN=NDUFA8 PE=1 SV=3 4.75 2342.9 - 1.19E+06 - - - -2.007 - 4.51 0.574 - 575.9 1 1 0 -0.0045 21 0 0 0 8.90E+07 5.68E+07 - - - 4.7189 0.9998 221125_WJC_METTL3_EV_vs_WT_F10.11841.11841.3 6.79E-09 21/60 K.HPELADKNVPNLHVMK.A "sp|Q9NQ39|RS10L_HUMAN,sp|P46783|RS10_HUMAN,tr|A0A2R8Y6L3|A0A2R8Y6L3_HUMAN,tr|F6U211|F6U211_HUMAN,tr|A0A1W2PQS6|A0A1W2PQS6_HUMAN,tr|A0A2R8YFH6|A0A2R8YFH6_HUMAN,tr|A0A2R8Y7H1|A0A2R8Y7H1_HUMAN,tr|S4R435|S4R435_HUMAN" 8 1840.9618 1.22 143411 11841 3 1840.958121 614.6612 Putative 40S ribosomal protein S10-like OS=Homo sapiens OX=9606 GN=RPS10P5 PE=5 SV=1 6.92 2344.2 - 1.05E+06 - - - -1.9919 - 3.434 0.479 - 468.3 1 2 1 -0.0037 16 0 0 0 3.11E+07 2.54E+07 - - - 7.0449 0.9866 221125_WJC_METTL3_EV_vs_WT_F10.11843.11843.3 0.00044 Oct-72 A.SESSKPWPDATYGTGSASR.A "sp|Q9Y2W1|TR150_HUMAN,tr|A0A3B3ITZ9|A0A3B3ITZ9_HUMAN" 2 1982.897 3.72 143412 11843 3 1982.892544 661.9729 Thyroid hormone receptor-associated protein 3 OS=Homo sapiens OX=9606 GN=THRAP3 PE=1 SV=2 5.79 2344.4 - 480956 - - - -2.2467 - 2.164 0.473 - 89 1 1 0 -0.0045 19 0 0 0 1.06E+07 2.84E+06 - - - 5.7088 0.9978 221125_WJC_METTL3_EV_vs_WT_F10.11845.11845.4 1.23E-07 25/120 R.PR[166.11]PDPSPEIEGDLQPATHGSR[166.11].F sp|P51970|NDUA8_HUMAN 1 2275.1096 1.57 143413 11845 4 2275.107077 569.7847 NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 8 OS=Homo sapiens OX=9606 GN=NDUFA8 PE=1 SV=3 4.75 2344.7 - 1.00E+06 - - - -1.1147 - 4.251 0.556 - 302.4 1 1 0 -0.0025 21 0 0 0 8.90E+07 5.65E+07 - - - 4.5432 1 221125_WJC_METTL3_EV_vs_WT_F10.11846.11846.3 6.27E-15 23/88 R.GSTPYSQDSAYSSSTTSTSFK[136.11]PR[166.11].R sp|O15047|SET1A_HUMAN 1 2459.1207 1.14 143414 11846 3 2459.114493 820.7142 Histone-lysine N-methyltransferase SETD1A OS=Homo sapiens OX=9606 GN=SETD1A PE=1 SV=3 8.5 2344.8 - 874009 - - - -2.5432 - 4.732 0.762 - 605 1 2 0 -0.0063 23 0 0 0 1.98E+07 1.74E+07 - - - 10.6802 1 221125_WJC_METTL3_EV_vs_WT_F10.11847.11847.3 1.09E-13 28/88 R.GSTPYSQDSAYSSSTTSTSFKPR.R sp|O15047|SET1A_HUMAN 1 2441.0983 1.14 143415 11847 3 2441.096224 814.7067 Histone-lysine N-methyltransferase SETD1A OS=Homo sapiens OX=9606 GN=SETD1A PE=1 SV=3 8.5 2344.9 - 1.18E+06 - - - -0.841 - 5.247 0.756 - 1159.3 1 2 0 -0.0021 23 0 0 0 1.98E+07 1.74E+07 - - - 10.8569 0.9982 221125_WJC_METTL3_EV_vs_WT_F10.11848.11848.3 8.55E-09 21/80 R.PRPDPSPEIEGDLQPATHGSR.F sp|P51970|NDUA8_HUMAN 1 2255.0931 1.66 143416 11848 3 2255.09573 752.705 NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 8 OS=Homo sapiens OX=9606 GN=NDUFA8 PE=1 SV=3 4.75 2345.1 - 562192 - - - 1.1782 - 3.837 0.526 - 291.9 1 1 0 0.0027 21 0 0 0 2.56E+07 1.54E+07 - - - 7.6275 1 221125_WJC_METTL3_EV_vs_WT_F10.11849.11849.3 3.54E-07 24/80 R.PR[166.11]PDPSPEIEGDLQPATHGSR[166.11].F sp|P51970|NDUA8_HUMAN 1 2275.1096 1.66 143417 11849 3 2275.105326 759.3771 NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 8 OS=Homo sapiens OX=9606 GN=NDUFA8 PE=1 SV=3 4.75 2345.2 - 462217 - - - -1.8843 - 4.021 0.639 - 465.7 1 1 0 -0.0043 21 0 0 0 2.56E+07 1.54E+07 - - - 8.9992 1 221125_WJC_METTL3_EV_vs_WT_F10.11860.11860.3 1.28E-06 18/64 R.C[160.03]SAGLGALAQRPGSVSK.W "sp|Q9NXV2|KCTD5_HUMAN,tr|H3BSS5|H3BSS5_HUMAN" 2 1657.857 6.18 143426 11860 3 1657.856394 553.6263 BTB\POZ domain-containing protein KCTD5 OS=Homo sapiens OX=9606 GN=KCTD5 PE=1 SV=1 9.51 2346.7 - 323494 - - - -0.3589 - 3.57 0.551 - 509.1 1 2 0 -0.0006 17 0 0 0 7.58E+06 1.23E+06 - - - 7.8978 0.9965 221125_WJC_METTL3_EV_vs_WT_F10.11872.11872.4 0.000953 15/90 K.NVMVEPHR[166.11]HEGVFIC[160.03]R[166.11].G "sp|P22087|FBRL_HUMAN,tr|M0R0P1|M0R0P1_HUMAN,tr|M0R1H0|M0R1H0_HUMAN,tr|M0QXL5|M0QXL5_HUMAN,tr|M0R2Q4|M0R2Q4_HUMAN,tr|M0R2B0|M0R2B0_HUMAN,tr|M0R2U2|M0R2U2_HUMAN" 7 1998.9783 1.03 143436 11872 4 1998.982414 500.7519 rRNA 2'-O-methyltransferase fibrillarin OS=Homo sapiens OX=9606 GN=FBL PE=1 SV=2 6.92 2348.2 - 326088 - - - 2.0355 - 2.363 0.321 - 226 1 2 1 0.0041 16 0 0 0 1.04E+07 1.00E+07 - - - 2.3218 0.9965 221125_WJC_METTL3_EV_vs_WT_F10.11877.11877.3 0.000608 Dec-64 R.TQHLSVETSYLQHESGR.L "sp|Q9Y276|BCS1_HUMAN,tr|C9J8G3|C9J8G3_HUMAN,tr|C9JAS4|C9JAS4_HUMAN,tr|A0A2R8Y7T3|A0A2R8Y7T3_HUMAN" 4 1970.9446 1.55 143439 11877 3 1971.950071 657.9888 Mitochondrial chaperone BCS1 OS=Homo sapiens OX=9606 GN=BCS1L PE=1 SV=1 5.94 2348.9 - 270783 - - - 510.1381 - 2.16 0.442 - 163.2 1 2 0 1.0055 17 0 0 0 5.73E+06 3.69E+06 - - - 5.1349 0.9992 221125_WJC_METTL3_EV_vs_WT_F10.11879.11879.4 0.00385 14/126 K.EETPGQRPAVTETHQLAELNEK.K "sp|Q9UQ35|SRRM2_HUMAN,tr|I3L1I8|I3L1I8_HUMAN,tr|I3L1C0|I3L1C0_HUMAN,tr|I3L4D8|I3L4D8_HUMAN,tr|I3L182|I3L182_HUMAN,tr|A0A087X1W1|A0A087X1W1_HUMAN" 6 2476.2194 0.93 143441 11879 4 2476.221712 620.0621 Serine\arginine repetitive matrix protein 2 OS=Homo sapiens OX=9606 GN=SRRM2 PE=1 SV=2 4.64 2349.1 - 858174 - - - 0.9357 - 2.977 0.293 - 91.7 1 2 0 0.0023 22 0 0 0 1.41E+07 1.52E+07 - - - 2.1326 0.9978 221125_WJC_METTL3_EV_vs_WT_F10.11880.11880.4 0.00131 16/96 R.TQHLSVETSYLQHESGR[166.11].L "sp|Q9Y276|BCS1_HUMAN,tr|C9J8G3|C9J8G3_HUMAN,tr|C9JAS4|C9JAS4_HUMAN,tr|A0A2R8Y7T3|A0A2R8Y7T3_HUMAN" 4 1980.9529 1.16 143442 11880 4 1980.954379 496.2455 Mitochondrial chaperone BCS1 OS=Homo sapiens OX=9606 GN=BCS1L PE=1 SV=1 5.94 2349.3 - 399771 - - - 0.7532 - 3.062 0.244 - 249.3 1 2 0 0.0015 17 0 0 0 1.19E+07 1.03E+07 - - - 1.7379 0.9998 221125_WJC_METTL3_EV_vs_WT_F10.11881.11881.3 4.88E-12 13/100 R.VTLLTPAGATGSGGGTSGDSSKGEDK.Q sp|Q9BZI7|REN3B_HUMAN 1 2349.1296 999 143443 11881 3 2349.136458 784.0505 Regulator of nonsense transcripts 3B OS=Homo sapiens OX=9606 GN=UPF3B PE=1 SV=1 4.56 2349.4 - 212319 - - - 2.9292 - 2.515 0.697 - 94.6 1 2 1 0.0069 26 0 0 0 2.67E+06 0.00E+00 - - - 8.4308 1 221125_WJC_METTL3_EV_vs_WT_F10.11888.11888.4 1.66E-09 22/138 K.TDHPEIGEGKPTPALSEASSSSIR.E "tr|A0A087WYS0|A0A087WYS0_HUMAN,tr|C9J406|C9J406_HUMAN" 2 2465.2034 1.22 143448 11888 4 2465.210769 617.3081 MICOS complex subunit MIC60 OS=Homo sapiens OX=9606 GN=IMMT PE=1 SV=1 4.83 2350.3 - 936651 - - - 2.9847 - 3.364 0.615 - 243.7 1 2 0 0.0074 24 0 0 0 4.56E+07 3.75E+07 - - - 4.9663 0.9995 221125_WJC_METTL3_EV_vs_WT_F10.11890.11890.4 1.24E-05 17/96 K.VRIDEYDYSKPIQGQQK.K "sp|P31040|SDHA_HUMAN,tr|A0A087X1I3|A0A087X1I3_HUMAN,tr|D6RFM5|D6RFM5_HUMAN" 3 2066.0433 0.49 143450 11890 4 2066.048994 517.5181 "Succinate dehydrogenase [ubiquinone] flavoprotein subunit, mitochondrial OS=Homo sapiens OX=9606 GN=SDHA PE=1 SV=2" 6.09 2350.6 - 284468 - - - 2.771 - 2.59 0.473 - 252.4 1 2 1 0.0057 17 0 0 0 8.47E+06 1.74E+07 - - - 3.6718 0.9999 221125_WJC_METTL3_EV_vs_WT_F10.11896.11896.3 1.31E-06 Nov-84 K.EETPGQR[166.11]PAVTETHQLAELNEK[136.11].K "sp|Q9UQ35|SRRM2_HUMAN,tr|I3L1I8|I3L1I8_HUMAN,tr|I3L1C0|I3L1C0_HUMAN,tr|I3L4D8|I3L4D8_HUMAN,tr|I3L182|I3L182_HUMAN,tr|A0A087X1W1|A0A087X1W1_HUMAN" 6 2494.2419 0.74 143454 11896 3 2494.248976 832.4212 Serine\arginine repetitive matrix protein 2 OS=Homo sapiens OX=9606 GN=SRRM2 PE=1 SV=2 4.64 2351.4 - 168621 - - - 2.851 - 2.328 0.544 - 96.2 1 2 0 0.0071 22 0 0 0 2.01E+06 2.73E+06 - - - 6.6065 1 221125_WJC_METTL3_EV_vs_WT_F10.11901.11901.4 1.40E-11 21/138 K.TDHPEIGEGK[136.11]PTPALSEASSSSIR[166.11].E "tr|A0A087WYS0|A0A087WYS0_HUMAN,tr|C9J406|C9J406_HUMAN" 2 2483.2259 1.21 143457 11901 4 2483.228263 621.8137 MICOS complex subunit MIC60 OS=Homo sapiens OX=9606 GN=IMMT PE=1 SV=1 4.83 2352.1 - 1.16E+06 - - - 0.9592 - 3.795 0.612 - 251.8 1 2 0 0.0024 24 0 0 0 4.56E+07 3.76E+07 - - - 4.9803 1 221125_WJC_METTL3_EV_vs_WT_F10.11906.11906.3 2.10E-09 16/92 K.TDHPEIGEGK[136.11]PTPALSEASSSSIR[166.11].E "tr|A0A087WYS0|A0A087WYS0_HUMAN,tr|C9J406|C9J406_HUMAN" 2 2483.2259 1.42 143462 11906 3 2483.23032 828.7492 MICOS complex subunit MIC60 OS=Homo sapiens OX=9606 GN=IMMT PE=1 SV=1 4.83 2352.8 - 159346 - - - 1.7876 - 3.287 0.651 - 176.1 1 2 0 0.0044 24 0 0 0 8.96E+06 6.32E+06 - - - 8.5606 1 221125_WJC_METTL3_EV_vs_WT_F10.11911.11911.3 3.66E-13 23/92 K.TDHPEIGEGKPTPALSEASSSSIR.E "tr|A0A087WYS0|A0A087WYS0_HUMAN,tr|C9J406|C9J406_HUMAN" 2 2465.2034 1.42 143465 11911 3 2465.212965 822.7417 MICOS complex subunit MIC60 OS=Homo sapiens OX=9606 GN=IMMT PE=1 SV=1 4.83 2353.4 - 360813 - - - 3.8755 - 3.984 0.662 - 526.5 1 2 0 0.0096 24 0 0 0 8.96E+06 6.32E+06 - - - 9.1285 0.9999 221125_WJC_METTL3_EV_vs_WT_F10.11920.11920.4 1.10E-07 20/144 R.ASPGHSPHYFAASSPTSPNALPPAR.K sp|Q8TEM1|PO210_HUMAN 1 2516.2197 3.04 143471 11920 4 2516.228744 630.0622 Nuclear pore membrane glycoprotein 210 OS=Homo sapiens OX=9606 GN=NUP210 PE=1 SV=3 8.8 2354.6 - 693475 - - - 3.6062 - 3.596 0.598 - 136.8 1 2 0 0.0091 25 0 0 0 8.61E+06 2.83E+06 - - - 4.8356 0.9995 221125_WJC_METTL3_EV_vs_WT_F10.11929.11929.3 3.48E-07 17/72 K.TQIQSQESDLKSQEDDLNR.A "sp|Q9UBC2|EP15R_HUMAN,tr|M0R2S2|M0R2S2_HUMAN,tr|M0R165|M0R165_HUMAN" 3 2233.0458 2.42 143478 11929 3 2233.054671 745.3559 Epidermal growth factor receptor substrate 15-like 1 OS=Homo sapiens OX=9606 GN=EPS15L1 PE=1 SV=1 4.1 2356 - 133294 - - - 3.9511 - 3.173 0.569 - 254.7 1 2 1 0.0088 19 0 0 0 2.61E+06 1.08E+06 - - - 7.7182 0.9424 221125_WJC_METTL3_EV_vs_WT_F10.11930.11930.4 0.00911 May-90 R.IVIHQSHPLQYIGHDR[166.11].T "sp|Q3KNV8|PCGF3_HUMAN,tr|C9J3G7|C9J3G7_HUMAN" 2 1922.015 1.34 143479 11930 4 1922.025202 481.511 Polycomb group RING finger protein 3 OS=Homo sapiens OX=9606 GN=PCGF3 PE=1 SV=1 7.02 2356.1 - 123363 - - - 5.2903 - 1.311 0.307 - 15.6 4 2 0 0.0102 16 0 0 0 2.27E+06 1.70E+06 - - - 1.5318 0.999 221125_WJC_METTL3_EV_vs_WT_F10.11932.11932.3 0.000121 Jul-92 K.GTMDDISQEEGSSQGEDSVSGSQR[166.11].L "sp|Q14683|SMC1A_HUMAN,tr|G8JLG1|G8JLG1_HUMAN,tr|A0A6Q8PHC3|A0A6Q8PHC3_HUMAN,tr|V9GY57|V9GY57_HUMAN" 4 2495.023 0.78 143481 11932 3 2495.035404 832.6816 Structural maintenance of chromosomes protein 1A OS=Homo sapiens OX=9606 GN=SMC1A PE=1 SV=2 3.71 2356.4 - 93180.8 - - - 4.9899 - 1.72 0.532 - 41.4 1 2 0 0.0124 24 0 0 0 2.70E+06 3.48E+06 - - - 5.7274 0.9984 221125_WJC_METTL3_EV_vs_WT_F10.11937.11937.3 0.011 May-88 K.FQPASAPAEDC[160.03]ISSSTEPK[136.11]PDPK[136.11].K sp|Q14008|CKAP5_HUMAN 1 2474.1606 2.46 143484 11937 3 2474.163732 825.7275 Cytoskeleton-associated protein 5 OS=Homo sapiens OX=9606 GN=CKAP5 PE=1 SV=3 4.32 2357.1 - 153206 - - - 1.2578 - 1.453 0.333 - 14.9 1 2 0 0.0031 23 0 0 0 4.40E+06 1.79E+06 - - - 3.1283 0.9999 221125_WJC_METTL3_EV_vs_WT_F10.11938.11938.3 0.00127 14/72 K.YNDDSDDSYFTSSSR[166.11]PTAR[166.11].R tr|H0Y6A0|H0Y6A0_HUMAN 1 2202.9205 1.03 143485 11938 3 2202.911871 735.3141 ADP-ribosylation factor GTPase-activating protein 3 (Fragment) OS=Homo sapiens OX=9606 GN=ARFGAP3 PE=1 SV=1 4.14 2357.2 - 262839 - - - -3.9053 - 2.766 0.598 - 223.6 1 2 0 -0.0086 19 0 0 0 8.83E+06 8.54E+06 - - - 7.7043 1 221125_WJC_METTL3_EV_vs_WT_F10.11939.11939.3 8.57E-08 13/72 K.YNDDSDDSYFTSSSRPTAR.R tr|H0Y6A0|H0Y6A0_HUMAN 1 2182.9039 1.01 143486 11939 3 2182.901253 728.6419 ADP-ribosylation factor GTPase-activating protein 3 (Fragment) OS=Homo sapiens OX=9606 GN=ARFGAP3 PE=1 SV=1 4.14 2357.3 - 209962 - - - -1.2282 - 2.717 0.68 - 229 1 2 0 -0.0027 19 0 0 0 8.87E+06 8.80E+06 - - - 8.5762 0.9953 221125_WJC_METTL3_EV_vs_WT_F10.11940.11940.3 0.00594 Jun-44 R.LLASTLVHSVK[136.11]K[136.11].E "sp|Q9NYF8|BCLF1_HUMAN,tr|E9PKI6|E9PKI6_HUMAN,tr|A0A1W2PQ43|A0A1W2PQ43_HUMAN,tr|E9PK91|E9PK91_HUMAN,tr|E9PJA7|E9PJA7_HUMAN,tr|E9PK09|E9PK09_HUMAN,tr|E9PQN2|E9PQN2_HUMAN" 7 1310.8257 1.87 143487 11940 3 1310.830597 437.9492 Bcl-2-associated transcription factor 1 OS=Homo sapiens OX=9606 GN=BCLAF1 PE=1 SV=2 10 2357.4 - 143327 - - - 3.7572 - 1.411 0.365 - 48.7 1 2 0 0.0049 12 0 0 0 2.23E+06 1.19E+06 - - - 3.5624 0.9994 221125_WJC_METTL3_EV_vs_WT_F10.11944.11944.4 7.10E-09 18/90 K.HPELADK[136.11]NVPNLHVMK[136.11].A "sp|Q9NQ39|RS10L_HUMAN,sp|P46783|RS10_HUMAN,tr|A0A2R8Y6L3|A0A2R8Y6L3_HUMAN,tr|F6U211|F6U211_HUMAN,tr|A0A1W2PQS6|A0A1W2PQS6_HUMAN,tr|A0A2R8YFH6|A0A2R8YFH6_HUMAN,tr|A0A2R8Y7H1|A0A2R8Y7H1_HUMAN,tr|S4R435|S4R435_HUMAN" 8 1856.9902 1.18 143490 11944 4 1856.99519 465.2548 Putative 40S ribosomal protein S10-like OS=Homo sapiens OX=9606 GN=RPS10P5 PE=5 SV=1 6.92 2357.9 - 1.36E+06 - - - 2.6936 - 3.265 0.442 - 294.8 1 2 1 0.005 16 0 0 0 2.17E+08 1.83E+08 - - - 3.4886 0.9996 221125_WJC_METTL3_EV_vs_WT_F10.11945.11945.3 2.54E-07 13/64 K.VR[166.11]IDEYDYSK[136.11]PIQGQQK[136.11].K "sp|P31040|SDHA_HUMAN,tr|A0A087X1I3|A0A087X1I3_HUMAN,tr|D6RFM5|D6RFM5_HUMAN" 3 2092.0799 0.57 143491 11945 3 2092.087319 698.3673 "Succinate dehydrogenase [ubiquinone] flavoprotein subunit, mitochondrial OS=Homo sapiens OX=9606 GN=SDHA PE=1 SV=2" 6.09 2358.1 - 194983 - - - 3.5276 - 2.651 0.583 - 184.7 1 2 1 0.0074 17 0 0 0 4.95E+06 8.69E+06 - - - 7.5008 0.9961 221125_WJC_METTL3_EV_vs_WT_F10.11950.11950.4 0.0303 Sep-78 K.SHLEVPLEENVNRR.V "sp|Q96CT7|CC124_HUMAN,tr|M0R2F5|M0R2F5_HUMAN" 2 1690.8751 0.73 143496 11950 4 1690.882635 423.726 Coiled-coil domain-containing protein 124 OS=Homo sapiens OX=9606 GN=CCDC124 PE=1 SV=1 5.47 2358.7 - 73290.1 - - - 4.4675 - 1.714 0.346 - 75.5 1 2 0 0.0076 14 0 0 0 1.30E+06 1.77E+06 - - - 2.4316 0.9994 221125_WJC_METTL3_EV_vs_WT_F10.11957.11957.3 0.00384 Aug-84 K.VDSDSSKPPETLTDPPGVC[160.03]QEK.V "sp|Q9Y520|PRC2C_HUMAN,tr|E7EPN9|E7EPN9_HUMAN,tr|H7C5N8|H7C5N8_HUMAN,tr|A0A2R8YET2|A0A2R8YET2_HUMAN" 4 2385.1006 2.47 143501 11957 3 2385.106855 796.0408 Protein PRRC2C OS=Homo sapiens OX=9606 GN=PRRC2C PE=1 SV=4 4.11 2359.6 - 174497 - - - 2.6284 - 1.919 0.402 - 39.3 1 2 0 0.0063 22 0 0 0 4.58E+07 1.85E+07 - - - 4.5655 0.9977 221125_WJC_METTL3_EV_vs_WT_F10.11961.11961.3 2.24E-06 Dec-88 R.QPPPAPPEQADGNAPGPQPPPVR.L sp|Q12948|FOXC1_HUMAN 1 2313.1502 5.59 143505 11961 3 2313.166537 772.0573 Forkhead box protein C1 OS=Homo sapiens OX=9606 GN=FOXC1 PE=1 SV=3 4.37 2360.1 - 107819 - - - 7.0653 - 2.23 0.518 - 95.4 1 2 0 0.0163 23 0 0 0 1.78E+06 3.19E+05 - - - 6.1921 0.9584 221125_WJC_METTL3_EV_vs_WT_F10.11971.11971.3 0.352 Jun-36 R.K[136.11]QDSGHLDLR[166.11].N "sp|Q86U44|MTA70_HUMAN,tr|B4E349|B4E349_HUMAN,tr|F5H6D8|F5H6D8_HUMAN,tr|B4DTN4|B4DTN4_HUMAN" 4 1185.6221 0.13 143513 11971 3 1185.624855 396.2146 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 6.75 2361.5 - 149111 - - - 2.3195 - 1.282 0.197 - 58.7 1 2 0 0.0027 10 0 0 0 1.30E+06 9.97E+06 - - - 1.4611 1 221125_WJC_METTL3_EV_vs_WT_F10.11977.11977.3 4.62E-09 25/76 K.ASESSKPWPDATYGTGSASR.A "sp|Q9Y2W1|TR150_HUMAN,tr|A0A3B3ITZ9|A0A3B3ITZ9_HUMAN" 2 2053.9341 3.03 143518 11977 3 2053.939087 685.652 Thyroid hormone receptor-associated protein 3 OS=Homo sapiens OX=9606 GN=THRAP3 PE=1 SV=2 6.11 2362.2 - 579722 - - - 2.4222 - 3.786 0.62 - 578.6 1 2 0 0.005 20 0 0 0 3.36E+07 1.11E+07 - - - 8.6808 0.9999 221125_WJC_METTL3_EV_vs_WT_F10.11979.11979.3 3.19E-06 Dec-92 K.GTMDDISQEEGSSQGEDSVSGSQR.L "sp|Q14683|SMC1A_HUMAN,tr|G8JLG1|G8JLG1_HUMAN,tr|A0A6Q8PHC3|A0A6Q8PHC3_HUMAN,tr|V9GY57|V9GY57_HUMAN" 4 2485.0147 0.78 143520 11979 3 2485.022034 829.3455 Structural maintenance of chromosomes protein 1A OS=Homo sapiens OX=9606 GN=SMC1A PE=1 SV=2 3.71 2362.5 - 261094 - - - 2.9577 - 1.972 0.571 - 124.3 1 2 0 0.0073 24 0 0 0 2.70E+06 3.48E+06 - - - 6.4812 1 221125_WJC_METTL3_EV_vs_WT_F10.11989.11989.3 2.16E-12 21/100 R.NEGQLNGETNTPIEGNQAGDAAASAR.S "sp|P18583|SON_HUMAN,tr|J3QSZ5|J3QSZ5_HUMAN" 2 2584.175 10.64 143528 11989 3 2584.181238 862.3989 Protein SON OS=Homo sapiens OX=9606 GN=SON PE=1 SV=4 4 2363.8 - 280941 - - - 2.4279 - 3.698 0.689 - 421.9 1 2 0 0.0063 26 0 0 0 3.70E+07 3.48E+06 - - - 9.2287 0.8086 221125_WJC_METTL3_EV_vs_WT_F10.11990.11990.4 0.0202 Oct-78 R.K[136.11]IELFGR[166.11]PHNVQPN.W sp|Q86U44|MTA70_HUMAN 1 1665.907 0.02 143529 11990 4 1665.910754 417.484 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 8.75 2364 - 207399 - - - 2.257 - 2.101 0.291 - 92.4 1 1 0 0.0038 14 0 0 0 9.01E+06 5.57E+08 - - - 2.028 1 221125_WJC_METTL3_EV_vs_WT_F10.11998.11998.4 1.62E-06 23/144 K.TDHPEIGEGK[136.11]PTPALSEEASSSSIR[166.11].E sp|Q16891|MIC60_HUMAN 1 2612.2685 1.56 143535 11998 4 2612.276086 654.0744 MICOS complex subunit MIC60 OS=Homo sapiens OX=9606 GN=IMMT PE=1 SV=1 4.57 2365 - 534183 - - - 2.9139 - 4.059 0.585 - 357.5 1 2 0 0.0076 25 0 0 0 3.10E+08 1.98E+08 - - - 4.7614 1 221125_WJC_METTL3_EV_vs_WT_F10.12000.12000.4 9.63E-08 21/144 K.TDHPEIGEGKPTPALSEEASSSSIR.E sp|Q16891|MIC60_HUMAN 1 2594.246 1.56 143537 12000 4 2594.253105 649.5688 MICOS complex subunit MIC60 OS=Homo sapiens OX=9606 GN=IMMT PE=1 SV=1 4.57 2365.3 - 647352 - - - 2.7372 - 3.497 0.583 - 262.3 1 2 0 0.0071 25 0 0 0 3.10E+08 1.98E+08 - - - 4.6967 1 221125_WJC_METTL3_EV_vs_WT_F10.12010.12010.4 1.28E-08 16/120 K.MGVSPGNPVDSHAYPHIQNSK.Q "sp|Q6W2J9|BCOR_HUMAN,tr|H7BZ37|H7BZ37_HUMAN,tr|H7C2V9|H7C2V9_HUMAN,tr|H7BYY2|H7BYY2_HUMAN,tr|H7C231|H7C231_HUMAN" 5 2234.0538 2.02 143544 12010 4 2234.058617 559.5207 BCL-6 corepressor OS=Homo sapiens OX=9606 GN=BCOR PE=1 SV=1 6.69 2366.6 - 302018 - - - 2.1338 - 3.041 0.602 - 180.2 1 2 0 0.0048 21 0 0 0 2.60E+07 1.29E+07 - - - 4.8322 1 221125_WJC_METTL3_EV_vs_WT_F10.12021.12021.3 1.20E-13 19/96 K.TDHPEIGEGK[136.11]PTPALSEEASSSSIR[166.11].E sp|Q16891|MIC60_HUMAN 1 2612.2685 1.26 143553 12021 3 2612.27676 871.7634 MICOS complex subunit MIC60 OS=Homo sapiens OX=9606 GN=IMMT PE=1 SV=1 4.57 2368.1 - 217946 - - - 3.172 - 3.586 0.589 - 312.2 1 2 0 0.0083 25 0 0 0 4.18E+07 3.32E+07 - - - 8.0425 1 221125_WJC_METTL3_EV_vs_WT_F10.12024.12024.3 3.31E-07 Nov-76 K.ASESSK[136.11]PWPDATYGTGSASR[166.11].A "sp|Q9Y2W1|TR150_HUMAN,tr|A0A3B3ITZ9|A0A3B3ITZ9_HUMAN" 2 2071.9566 3.4 143556 12024 3 2071.960998 691.6595 Thyroid hormone receptor-associated protein 3 OS=Homo sapiens OX=9606 GN=THRAP3 PE=1 SV=2 6.11 2368.5 - 156814 - - - 2.1313 - 2.646 0.54 - 100.7 1 2 0 0.0044 20 0 0 0 3.04E+07 8.93E+06 - - - 6.9199 1 221125_WJC_METTL3_EV_vs_WT_F10.12027.12027.4 1.02E-06 Nov-84 R.C[160.03]RDDSFFGETSHNYH.K "sp|P43243|MATR3_HUMAN,tr|A8MXP9|A8MXP9_HUMAN,tr|D6R991|D6R991_HUMAN,tr|A0A0R4J2E8|A0A0R4J2E8_HUMAN,tr|H0Y8T4|H0Y8T4_HUMAN,tr|D6REM6|D6REM6_HUMAN" 6 1870.7329 1 143557 12027 4 1870.733378 468.6905 Matrin-3 OS=Homo sapiens OX=9606 GN=MATR3 PE=1 SV=2 5.21 2368.9 - 352024 - - - 0.2502 - 2.476 0.634 - 114.2 1 1 1 0.0005 15 0 0 0 1.64E+07 1.64E+07 - - - 5.0686 0.9918 221125_WJC_METTL3_EV_vs_WT_F10.12030.12030.2 4.14E-06 26-Sep R.K[136.11]IELFGR[166.11]PHNVQPN.W sp|Q86U44|MTA70_HUMAN 1 1665.907 0.001 143560 12030 2 1665.908121 833.9608 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 8.75 2369.3 - 236103 - - - 0.6765 - 2.072 0.543 - 166 1 1 0 0.0011 14 0 0 0 0.00E+00 3.13E+07 - - - 4.8794 1 221125_WJC_METTL3_EV_vs_WT_F10.12031.12031.3 1.11E-11 16/88 K.SSSADFGTFNTSQSHQTASAVSK.V "sp|P52594|AGFG1_HUMAN,tr|B8ZZY2|B8ZZY2_HUMAN,tr|C9J2I0|C9J2I0_HUMAN" 3 2344.0567 1.6 143561 12031 3 2344.061854 782.3595 Arf-GAP domain and FG repeat-containing protein 1 OS=Homo sapiens OX=9606 GN=AGFG1 PE=1 SV=2 6.46 2369.4 - 215279 - - - 2.1787 - 3.384 0.719 - 246.9 1 2 0 0.0051 23 0 0 0 2.78E+06 1.74E+06 - - - 9.4146 0.9984 221125_WJC_METTL3_EV_vs_WT_F10.12032.12032.3 1.88E-05 Sep-68 K.TGQELQSAC[160.03]DALK[136.11]DQNSK[136.11].L "sp|Q14789|GOGB1_HUMAN,tr|E7EU81|E7EU81_HUMAN,tr|H0Y867|H0Y867_HUMAN" 3 2007.9502 1.7 143562 12032 3 2007.942308 670.324 Golgin subfamily B member 1 OS=Homo sapiens OX=9606 GN=GOLGB1 PE=1 SV=2 4.56 2369.6 - 160397 - - - -3.9468 - 2.005 0.514 - 92 1 2 1 -0.0079 18 0 0 0 2.55E+06 1.50E+06 - - - 6.0006 1 221125_WJC_METTL3_EV_vs_WT_F10.12038.12038.3 8.60E-09 16/56 R.C[160.03]RDDSFFGETSHNYH.K "sp|P43243|MATR3_HUMAN,tr|A8MXP9|A8MXP9_HUMAN,tr|D6R991|D6R991_HUMAN,tr|A0A0R4J2E8|A0A0R4J2E8_HUMAN,tr|H0Y8T4|H0Y8T4_HUMAN,tr|D6REM6|D6REM6_HUMAN" 6 1870.7329 1.12 143566 12038 3 1870.736789 624.5849 Matrin-3 OS=Homo sapiens OX=9606 GN=MATR3 PE=1 SV=2 5.21 2370.4 - 412538 - - - 2.0735 - 3.058 0.724 - 359.3 1 1 1 0.0039 15 0 0 0 1.22E+07 1.09E+07 - - - 9.5275 0.9999 221125_WJC_METTL3_EV_vs_WT_F10.12044.12044.4 3.12E-08 20/90 K.IFVGGIK[136.11]EDTEEHHLR[166.11].D "sp|Q32P51|RA1L2_HUMAN,sp|P09651|ROA1_HUMAN,sp|P22626|ROA2_HUMAN,tr|A0A7I2YQN4|A0A7I2YQN4_HUMAN,tr|A0A7I2YQX9|A0A7I2YQX9_HUMAN,tr|A0A7I2V4N0|A0A7I2V4N0_HUMAN,tr|A0A024RA28|A0A024RA28_HUMAN,tr|A0A7I2V4N1|A0A7I2V4N1_HUMAN,tr|A0A7I2V4I6|A0A7I2V4I6_HUMAN,tr|F8VZ49|F8VZ49_HUMAN,tr|A0A7I2V3R8|A0A7I2V3R8_HUMAN,tr|A0A087WUI2|A0A087WUI2_HUMAN,tr|A0A7I2V4S4|A0A7I2V4S4_HUMAN,tr|F8VTQ5|F8VTQ5_HUMAN,tr|F8W6I7|F8W6I7_HUMAN,tr|A0A7I2V2L6|A0A7I2V2L6_HUMAN,tr|A0A7I2V323|A0A7I2V323_HUMAN,tr|A0A7I2V3W0|A0A7I2V3W0_HUMAN,tr|A0A7I2V5U9|A0A7I2V5U9_HUMAN,tr|A0A2R8Y4L2|A0A2R8Y4L2_HUMAN,tr|A0A7I2V3P1|A0A7I2V3P1_HUMAN,tr|A0A7I2V3P7|A0A7I2V3P7_HUMAN" 22 1896.9813 1.32 143570 12044 4 1896.980827 475.2526 Heterogeneous nuclear ribonucleoprotein A1-like 2 OS=Homo sapiens OX=9606 GN=HNRNPA1L2 PE=2 SV=2 5.36 2371.1 - 593766 - - - -0.2393 - 3.421 0.589 - 315.2 1 2 1 -0.0005 16 0 0 0 3.81E+07 2.89E+07 - - - 4.7858 0.993 221125_WJC_METTL3_EV_vs_WT_F10.12047.12047.4 4.15E-06 Dec-84 R.C[160.03]R[166.11]DDSFFGETSHNYH.K "sp|P43243|MATR3_HUMAN,tr|A8MXP9|A8MXP9_HUMAN,tr|D6R991|D6R991_HUMAN,tr|A0A0R4J2E8|A0A0R4J2E8_HUMAN,tr|H0Y8T4|H0Y8T4_HUMAN,tr|D6REM6|D6REM6_HUMAN" 6 1880.7412 0.99 143573 12047 4 1880.740483 471.1926 Matrin-3 OS=Homo sapiens OX=9606 GN=MATR3 PE=1 SV=2 5.21 2371.5 - 705324 - - - -0.3706 - 2.212 0.607 - 113.3 1 1 1 -0.0007 15 0 0 0 1.64E+07 1.65E+07 - - - 4.7932 1 221125_WJC_METTL3_EV_vs_WT_F10.12064.12064.3 2.38E-09 15/56 R.C[160.03]R[166.11]DDSFFGETSHNYH.K "sp|P43243|MATR3_HUMAN,tr|A8MXP9|A8MXP9_HUMAN,tr|D6R991|D6R991_HUMAN,tr|A0A0R4J2E8|A0A0R4J2E8_HUMAN,tr|H0Y8T4|H0Y8T4_HUMAN,tr|D6REM6|D6REM6_HUMAN" 6 1880.7412 1.12 143583 12064 3 1880.739432 627.921 Matrin-3 OS=Homo sapiens OX=9606 GN=MATR3 PE=1 SV=2 5.21 2373.7 - 442883 - - - -0.9294 - 2.934 0.748 - 251 1 1 1 -0.0017 15 0 0 0 1.22E+07 1.09E+07 - - - 9.6876 0.9878 221125_WJC_METTL3_EV_vs_WT_F10.12067.12067.2 1.8 22-Jul R.K[136.11]LEEDLLVEVSR.Y sp|Q9Y259|CHKB_HUMAN 1 1436.7966 - 143584 12067 2 1436.797847 719.4056 Choline\ethanolamine kinase OS=Homo sapiens OX=9606 GN=CHKB PE=1 SV=3 4.41 2374.1 - 453170 - - - 0.8609 - 1.413 0.11 - 100.8 2 2 0 0.0012 12 0 0 0 - - - - - 0.6282 0.9987 221125_WJC_METTL3_EV_vs_WT_F10.12075.12075.4 8.38E-08 15/120 K.MGVSPGNPVDSHAYPHIQNSK[136.11].Q "sp|Q6W2J9|BCOR_HUMAN,tr|H7BZ37|H7BZ37_HUMAN,tr|H7C2V9|H7C2V9_HUMAN,tr|H7BYY2|H7BYY2_HUMAN,tr|H7C231|H7C231_HUMAN" 5 2242.068 2 143588 12075 4 2243.067699 561.5243 BCL-6 corepressor OS=Homo sapiens OX=9606 GN=BCOR PE=1 SV=1 6.69 2375.1 - 335477 - - - 445.8602 - 3.017 0.529 - 149 1 2 0 0.9996 21 0 0 0 2.58E+07 1.29E+07 - - - 3.9186 1 221125_WJC_METTL3_EV_vs_WT_F10.12077.12077.3 2.25E-16 26/80 R.TR[166.11]EEEC[160.03]HFYAGGQVYPGEASR[166.11].V "sp|Q13162|PRDX4_HUMAN,tr|A6NG45|A6NG45_HUMAN" 2 2462.0824 0.59 143589 12077 3 2462.076233 821.7014 Peroxiredoxin-4 OS=Homo sapiens OX=9606 GN=PRDX4 PE=1 SV=1 4.9 2375.5 - 475682 - - - -2.5097 - 4.599 0.781 - 1083.4 1 2 1 -0.0062 21 0 0 0 8.56E+06 1.45E+07 - - - 10.9038 0.9999 221125_WJC_METTL3_EV_vs_WT_F10.12082.12082.3 1.16E-05 16/60 K.IFVGGIKEDTEEHHLR.D "sp|Q32P51|RA1L2_HUMAN,sp|P09651|ROA1_HUMAN,sp|P22626|ROA2_HUMAN,tr|A0A7I2YQN4|A0A7I2YQN4_HUMAN,tr|A0A7I2YQX9|A0A7I2YQX9_HUMAN,tr|A0A7I2V4N0|A0A7I2V4N0_HUMAN,tr|A0A024RA28|A0A024RA28_HUMAN,tr|A0A7I2V4N1|A0A7I2V4N1_HUMAN,tr|A0A7I2V4I6|A0A7I2V4I6_HUMAN,tr|F8VZ49|F8VZ49_HUMAN,tr|A0A7I2V3R8|A0A7I2V3R8_HUMAN,tr|A0A087WUI2|A0A087WUI2_HUMAN,tr|A0A7I2V4S4|A0A7I2V4S4_HUMAN,tr|F8VTQ5|F8VTQ5_HUMAN,tr|F8W6I7|F8W6I7_HUMAN,tr|A0A7I2V2L6|A0A7I2V2L6_HUMAN,tr|A0A7I2V323|A0A7I2V323_HUMAN,tr|A0A7I2V3W0|A0A7I2V3W0_HUMAN,tr|A0A7I2V5U9|A0A7I2V5U9_HUMAN,tr|A0A2R8Y4L2|A0A2R8Y4L2_HUMAN,tr|A0A7I2V3P1|A0A7I2V3P1_HUMAN,tr|A0A7I2V3P7|A0A7I2V3P7_HUMAN" 22 1878.9588 2.56 143592 12082 3 1878.957163 627.3269 Heterogeneous nuclear ribonucleoprotein A1-like 2 OS=Homo sapiens OX=9606 GN=HNRNPA1L2 PE=2 SV=2 5.36 2376.1 - 313499 - - - -0.8771 - 2.807 0.515 - 222.7 1 2 1 -0.0016 16 0 0 0 8.78E+06 3.43E+06 - - - 6.9296 1 221125_WJC_METTL3_EV_vs_WT_F10.12084.12084.3 1.54E-14 25/80 R.TREEEC[160.03]HFYAGGQVYPGEASR.V "sp|Q13162|PRDX4_HUMAN,tr|A6NG45|A6NG45_HUMAN" 2 2442.0659 0.59 143594 12084 3 2442.075859 815.0292 Peroxiredoxin-4 OS=Homo sapiens OX=9606 GN=PRDX4 PE=1 SV=1 4.9 2376.3 - 300756 - - - 4.0896 - 4.418 0.746 - 960.2 1 2 1 0.01 21 0 0 0 8.56E+06 1.45E+07 - - - 10.4163 1 221125_WJC_METTL3_EV_vs_WT_F10.12087.12087.3 5.47E-19 31/96 K.TDHPEIGEGKPTPALSEEASSSSIR.E sp|Q16891|MIC60_HUMAN 1 2594.246 1.26 143595 12087 3 2594.247523 865.7559 MICOS complex subunit MIC60 OS=Homo sapiens OX=9606 GN=IMMT PE=1 SV=1 4.57 2376.7 - 1.31E+06 - - - 0.5855 - 4.882 0.718 - 1016.3 1 2 0 0.0015 25 0 0 0 4.18E+07 3.31E+07 - - - 10.1924 0.9999 221125_WJC_METTL3_EV_vs_WT_F10.12098.12098.3 0.000137 7/116 R.KVDC[160.03]PGPGSGAEGSGPGSVVPGSSGVGTPR.Q "sp|O00268|TAF4_HUMAN,tr|A0A0G2JRY5|A0A0G2JRY5_HUMAN" 2 2708.2824 1.87 143602 12098 3 2708.284273 903.7681 Transcription initiation factor TFIID subunit 4 OS=Homo sapiens OX=9606 GN=TAF4 PE=1 SV=2 6.06 2378.2 - 141337 - - - 0.689 - 1.616 0.489 - 20.8 1 2 0 0.0019 30 0 0 0 2.49E+07 1.33E+07 - - - 5.0955 0.9996 221125_WJC_METTL3_EV_vs_WT_F10.12102.12102.3 1.00E-05 Oct-60 K.IFVGGIK[136.11]EDTEEHHLR[166.11].D "sp|Q32P51|RA1L2_HUMAN,sp|P09651|ROA1_HUMAN,sp|P22626|ROA2_HUMAN,tr|A0A7I2YQN4|A0A7I2YQN4_HUMAN,tr|A0A7I2YQX9|A0A7I2YQX9_HUMAN,tr|A0A7I2V4N0|A0A7I2V4N0_HUMAN,tr|A0A024RA28|A0A024RA28_HUMAN,tr|A0A7I2V4N1|A0A7I2V4N1_HUMAN,tr|A0A7I2V4I6|A0A7I2V4I6_HUMAN,tr|F8VZ49|F8VZ49_HUMAN,tr|A0A7I2V3R8|A0A7I2V3R8_HUMAN,tr|A0A087WUI2|A0A087WUI2_HUMAN,tr|A0A7I2V4S4|A0A7I2V4S4_HUMAN,tr|F8VTQ5|F8VTQ5_HUMAN,tr|F8W6I7|F8W6I7_HUMAN,tr|A0A7I2V2L6|A0A7I2V2L6_HUMAN,tr|A0A7I2V323|A0A7I2V323_HUMAN,tr|A0A7I2V3W0|A0A7I2V3W0_HUMAN,tr|A0A7I2V5U9|A0A7I2V5U9_HUMAN,tr|A0A2R8Y4L2|A0A2R8Y4L2_HUMAN,tr|A0A7I2V3P1|A0A7I2V3P1_HUMAN,tr|A0A7I2V3P7|A0A7I2V3P7_HUMAN" 22 1896.9813 2.56 143604 12102 3 1896.984721 633.3344 Heterogeneous nuclear ribonucleoprotein A1-like 2 OS=Homo sapiens OX=9606 GN=HNRNPA1L2 PE=2 SV=2 5.36 2378.7 - 220487 - - - 1.8134 - 2.288 0.479 - 106.7 1 2 1 0.0034 16 0 0 0 8.78E+06 3.43E+06 - - - 6.0031 0.9999 221125_WJC_METTL3_EV_vs_WT_F10.12104.12104.4 1.47E-06 17/120 R.TR[166.11]EEEC[160.03]HFYAGGQVYPGEASR[166.11].V "sp|Q13162|PRDX4_HUMAN,tr|A6NG45|A6NG45_HUMAN" 2 2462.0824 1.05 143605 12104 4 2462.085463 616.5279 Peroxiredoxin-4 OS=Homo sapiens OX=9606 GN=PRDX4 PE=1 SV=1 4.9 2379 - 2.73E+06 - - - 1.2392 - 3.077 0.555 - 134.3 1 2 1 0.0031 21 0 0 0 2.76E+07 2.63E+07 - - - 4.4275 0.9999 221125_WJC_METTL3_EV_vs_WT_F10.12105.12105.4 4.62E-09 13/120 K.KTEAELSQDLETSPTAKPQIK.T "sp|Q5VT06|CE350_HUMAN,tr|H0Y7F7|H0Y7F7_HUMAN" 2 2313.2064 2.18 143606 12105 4 2313.212848 579.3089 Centrosome-associated protein 350 OS=Homo sapiens OX=9606 GN=CEP350 PE=1 SV=1 4.87 2379.1 - 346498 - - - 2.8 - 3.126 0.542 - 106.8 1 2 0 0.0065 21 0 0 0 6.27E+06 2.87E+06 - - - 4.3186 1 221125_WJC_METTL3_EV_vs_WT_F10.12106.12106.3 7.65E-08 15/60 R.RRPYNDDADIDYINER.N sp|O95926|SYF2_HUMAN 1 2023.9348 6.23 143607 12106 3 2023.937983 675.6522 Pre-mRNA-splicing factor SYF2 OS=Homo sapiens OX=9606 GN=SYF2 PE=1 SV=1 4.36 2379.2 - 229138 - - - 1.5821 - 2.623 0.54 - 204 1 2 0 0.0032 16 0 0 0 4.19E+06 6.73E+05 - - - 7.0339 0.9998 221125_WJC_METTL3_EV_vs_WT_F10.12110.12110.4 6.84E-06 13/120 K.K[136.11]TEAELSQDLETSPTAK[136.11]PQIK[136.11].T "sp|Q5VT06|CE350_HUMAN,tr|H0Y7F7|H0Y7F7_HUMAN" 2 2337.249 2.18 143609 12110 4 2337.256957 585.3195 Centrosome-associated protein 350 OS=Homo sapiens OX=9606 GN=CEP350 PE=1 SV=1 4.87 2379.8 - 208449 - - - 3.4168 - 2.711 0.47 - 119.4 1 2 0 0.008 21 0 0 0 6.27E+06 2.87E+06 - - - 3.6444 0.999 221125_WJC_METTL3_EV_vs_WT_F10.12116.12116.4 0.00967 Jul-78 R.DDSFFGETSHNYHK[136.11].F "sp|P43243|MATR3_HUMAN,tr|A8MXP9|A8MXP9_HUMAN,tr|D6R991|D6R991_HUMAN,tr|A0A0R4J2E8|A0A0R4J2E8_HUMAN,tr|H0Y8T4|H0Y8T4_HUMAN,tr|D6REM6|D6REM6_HUMAN" 6 1690.7103 1.35 143613 12116 4 1690.711847 423.6849 Matrin-3 OS=Homo sapiens OX=9606 GN=MATR3 PE=1 SV=2 5.21 2380.6 - 183714 - - - 0.9067 - 1.338 0.313 - 18.4 1 2 0 0.0015 14 0 0 0 1.92E+07 1.42E+07 - - - 2.0559 0.9998 221125_WJC_METTL3_EV_vs_WT_F10.12119.12119.3 0.00272 15/56 R.R[166.11]NLDIER[166.11]PTYTNLNR[166.11].L "sp|Q9NY65|TBA8_HUMAN,sp|Q6PEY2|TBA3E_HUMAN,sp|P0DPH7|TBA3C_HUMAN,sp|Q71U36|TBA1A_HUMAN,sp|P0DPH8|TBA3D_HUMAN,sp|P68366|TBA4A_HUMAN,sp|P68363|TBA1B_HUMAN,sp|Q9BQE3|TBA1C_HUMAN,tr|F8VVB9|F8VVB9_HUMAN,tr|C9JDS9|C9JDS9_HUMAN,tr|A0A7P0TA31|A0A7P0TA31_HUMAN,tr|F5H5D3|F5H5D3_HUMAN,tr|C9J2C0|C9J2C0_HUMAN,tr|F8VQQ4|F8VQQ4_HUMAN,tr|A0A7P0T945|A0A7P0T945_HUMAN" 15 1904.0007 0.48 143615 12119 3 1904.005002 635.6742 Tubulin alpha-8 chain OS=Homo sapiens OX=9606 GN=TUBA8 PE=1 SV=1 8.74 2381 - 307671 - - - 2.2763 - 2.623 0.393 - 140.7 1 2 0 0.0043 15 0 0 0 2.40E+06 5.00E+06 - - - 5.4366 1 221125_WJC_METTL3_EV_vs_WT_F10.12120.12120.3 1.02E-08 19/116 R.K[136.11]VDC[160.03]PGPGSGAEGSGPGSVVPGSSGVGTPR[166.11].Q "sp|O00268|TAF4_HUMAN,tr|A0A0G2JRY5|A0A0G2JRY5_HUMAN" 2 2726.3049 1.87 143616 12120 3 2726.305116 909.7756 Transcription initiation factor TFIID subunit 4 OS=Homo sapiens OX=9606 GN=TAF4 PE=1 SV=2 6.06 2381.1 - 334262 - - - 0.0877 - 3.392 0.672 - 155.8 1 2 0 0.0002 30 0 0 0 2.49E+07 1.33E+07 - - - 8.8421 1 221125_WJC_METTL3_EV_vs_WT_F10.12125.12125.3 1.06E-08 13/52 R.DDSFFGETSHNYHK[136.11].F "sp|P43243|MATR3_HUMAN,tr|A8MXP9|A8MXP9_HUMAN,tr|D6R991|D6R991_HUMAN,tr|A0A0R4J2E8|A0A0R4J2E8_HUMAN,tr|H0Y8T4|H0Y8T4_HUMAN,tr|D6REM6|D6REM6_HUMAN" 6 1690.7103 1.4 143619 12125 3 1690.711007 564.5774 Matrin-3 OS=Homo sapiens OX=9606 GN=MATR3 PE=1 SV=2 5.21 2381.8 - 478804 - - - 0.4099 - 2.466 0.652 - 174.8 1 2 0 0.0007 14 0 0 0 2.53E+07 1.81E+07 - - - 8.2076 0.9993 221125_WJC_METTL3_EV_vs_WT_F10.12129.12129.3 0.00574 Aug-56 R.RNLDIERPTYTNLNR.L "sp|Q9NY65|TBA8_HUMAN,sp|Q6PEY2|TBA3E_HUMAN,sp|P0DPH7|TBA3C_HUMAN,sp|Q71U36|TBA1A_HUMAN,sp|P0DPH8|TBA3D_HUMAN,sp|P68366|TBA4A_HUMAN,sp|P68363|TBA1B_HUMAN,sp|Q9BQE3|TBA1C_HUMAN,tr|F8VVB9|F8VVB9_HUMAN,tr|C9JDS9|C9JDS9_HUMAN,tr|A0A7P0TA31|A0A7P0TA31_HUMAN,tr|F5H5D3|F5H5D3_HUMAN,tr|C9J2C0|C9J2C0_HUMAN,tr|F8VQQ4|F8VQQ4_HUMAN,tr|A0A7P0T945|A0A7P0T945_HUMAN" 15 1873.9759 0.48 143623 12129 3 1873.979208 625.6659 Tubulin alpha-8 chain OS=Homo sapiens OX=9606 GN=TUBA8 PE=1 SV=1 8.74 2382.3 - 234509 - - - 1.7876 - 1.825 0.344 - 39.4 1 2 0 0.0034 15 0 0 0 2.40E+06 5.00E+06 - - - 3.9441 0.9999 221125_WJC_METTL3_EV_vs_WT_F10.12130.12130.3 0.0015 Dec-40 R.SLGTADVHFER[166.11].K "sp|Q86V81|THOC4_HUMAN,tr|E9PB61|E9PB61_HUMAN" 2 1240.6076 0.75 143624 12130 3 1240.609935 414.5431 THO complex subunit 4 OS=Homo sapiens OX=9606 GN=ALYREF PE=1 SV=3 5.3 2382.4 - 232381 - - - 1.9063 - 2.238 0.498 - 180.4 1 2 0 0.0024 11 0 0 0 2.89E+06 3.83E+06 - - - 6.3801 1 221125_WJC_METTL3_EV_vs_WT_F10.12137.12137.3 9.64E-07 17/52 R.DDSFFGETSHNYHK.F "sp|P43243|MATR3_HUMAN,tr|A8MXP9|A8MXP9_HUMAN,tr|D6R991|D6R991_HUMAN,tr|A0A0R4J2E8|A0A0R4J2E8_HUMAN,tr|H0Y8T4|H0Y8T4_HUMAN,tr|D6REM6|D6REM6_HUMAN" 6 1682.6961 1.41 143629 12137 3 1682.69788 561.906 Matrin-3 OS=Homo sapiens OX=9606 GN=MATR3 PE=1 SV=2 5.21 2383.4 - 1.46E+06 - - - 1.0495 - 3.247 0.642 - 355.1 1 2 0 0.0018 14 0 0 0 2.55E+07 1.81E+07 - - - 8.827 1 221125_WJC_METTL3_EV_vs_WT_F10.12142.12142.3 4.51E-16 25/112 K.GGGSAAAAAAAAASGGAGSDNSVEHSDYR.A "sp|P40424|PBX1_HUMAN,tr|H0YLB0|H0YLB0_HUMAN,tr|H0YLF5|H0YLF5_HUMAN,tr|H0YLD4|H0YLD4_HUMAN,tr|H0YKH1|H0YKH1_HUMAN,tr|H0YLM3|H0YLM3_HUMAN,tr|F8WA05|F8WA05_HUMAN,tr|H0YLT4|H0YLT4_HUMAN,tr|A0A087X0P4|A0A087X0P4_HUMAN,tr|A0A0A0MTI0|A0A0A0MTI0_HUMAN" 10 2534.1018 1.41 143634 12142 3 2534.106706 845.7079 Pre-B-cell leukemia transcription factor 1 OS=Homo sapiens OX=9606 GN=PBX1 PE=1 SV=1 4.54 2384 - 371817 - - - 1.936 - 4.685 0.718 - 462.7 1 2 0 0.0049 29 0 0 0 2.95E+06 2.09E+06 - - - 10.0967 0.9999 221125_WJC_METTL3_EV_vs_WT_F10.12153.12153.4 9.38E-10 18/90 K.IFVGGIKEDTEEHHLR.D "sp|Q32P51|RA1L2_HUMAN,sp|P09651|ROA1_HUMAN,sp|P22626|ROA2_HUMAN,tr|A0A7I2YQN4|A0A7I2YQN4_HUMAN,tr|A0A7I2YQX9|A0A7I2YQX9_HUMAN,tr|A0A7I2V4N0|A0A7I2V4N0_HUMAN,tr|A0A024RA28|A0A024RA28_HUMAN,tr|A0A7I2V4N1|A0A7I2V4N1_HUMAN,tr|A0A7I2V4I6|A0A7I2V4I6_HUMAN,tr|F8VZ49|F8VZ49_HUMAN,tr|A0A7I2V3R8|A0A7I2V3R8_HUMAN,tr|A0A087WUI2|A0A087WUI2_HUMAN,tr|A0A7I2V4S4|A0A7I2V4S4_HUMAN,tr|F8VTQ5|F8VTQ5_HUMAN,tr|F8W6I7|F8W6I7_HUMAN,tr|A0A7I2V2L6|A0A7I2V2L6_HUMAN,tr|A0A7I2V323|A0A7I2V323_HUMAN,tr|A0A7I2V3W0|A0A7I2V3W0_HUMAN,tr|A0A7I2V5U9|A0A7I2V5U9_HUMAN,tr|A0A2R8Y4L2|A0A2R8Y4L2_HUMAN,tr|A0A7I2V3P1|A0A7I2V3P1_HUMAN,tr|A0A7I2V3P7|A0A7I2V3P7_HUMAN" 22 1878.9588 1.29 143644 12153 4 1878.960585 470.747 Heterogeneous nuclear ribonucleoprotein A1-like 2 OS=Homo sapiens OX=9606 GN=HNRNPA1L2 PE=2 SV=2 5.36 2385.4 - 485743 - - - 0.9441 - 3.455 0.602 - 318.7 1 2 1 0.0018 16 0 0 0 3.81E+07 2.95E+07 - - - 4.9021 0.9824 221125_WJC_METTL3_EV_vs_WT_F10.12157.12157.4 0.183 14/114 K.VVTTNYKPVANHQYNIEYER.K sp|P13984|T2FB_HUMAN 1 2437.2026 0.91 143648 12157 4 2437.203248 610.3079 General transcription factor IIF subunit 2 OS=Homo sapiens OX=9606 GN=GTF2F2 PE=1 SV=2 6.72 2385.8 - 752354 - - - 0.2564 - 1.664 0.181 - 88.7 1 2 0 0.0006 20 0 0 0 4.48E+06 4.90E+06 - - - 0.9715 0.9999 221125_WJC_METTL3_EV_vs_WT_F10.12159.12159.4 2.57E-05 12/114 K.VVTTNYK[136.11]PVANHQYNIEYER[166.11].K sp|P13984|T2FB_HUMAN 1 2455.2251 0.93 143650 12159 4 2455.225406 614.8135 General transcription factor IIF subunit 2 OS=Homo sapiens OX=9606 GN=GTF2F2 PE=1 SV=2 6.72 2386.1 - 466546 - - - 0.1275 - 2.364 0.413 - 77.6 1 2 0 0.0003 20 0 0 0 4.48E+06 4.81E+06 - - - 3.1083 1 221125_WJC_METTL3_EV_vs_WT_F10.12163.12163.3 3.40E-05 13/40 R.SLGTADVHFER.K "sp|Q86V81|THOC4_HUMAN,tr|E9PB61|E9PB61_HUMAN" 2 1230.5993 0.77 143654 12163 3 1230.598974 411.207 THO complex subunit 4 OS=Homo sapiens OX=9606 GN=ALYREF PE=1 SV=3 5.3 2386.6 - 362987 - - - -0.2649 - 2.524 0.509 - 211 1 2 0 -0.0003 11 0 0 0 2.99E+06 3.86E+06 - - - 6.8449 0.7739 221125_WJC_METTL3_EV_vs_WT_F10.12164.12164.2 0.204 14-Jun T.LVPEQIGK.L "sp|O75674|TM1L1_HUMAN,tr|J3KQU4|J3KQU4_HUMAN,tr|I3L367|I3L367_HUMAN,tr|I3NI44|I3NI44_HUMAN,tr|I3L4I4|I3L4I4_HUMAN,tr|I3L3T4|I3L3T4_HUMAN,tr|I3L1G1|I3L1G1_HUMAN" 7 882.5175 43.95 143655 12164 2 882.517285 442.266 TOM1-like protein 1 OS=Homo sapiens OX=9606 GN=TOM1L1 PE=1 SV=2 6 2386.7 - 330876 - - - -0.2074 - 0.997 0.283 - 133.8 1 1 0 -0.0002 8 0 0 0 2.49E+07 5.67E+05 - - - 1.1221 1 221125_WJC_METTL3_EV_vs_WT_F10.12165.12165.4 0.000649 15/144 R.ASPGHSPHYFAASSPTSPNALPPAR.K sp|Q8TEM1|PO210_HUMAN 1 2516.2197 3.31 143656 12165 4 2516.22179 630.0622 Nuclear pore membrane glycoprotein 210 OS=Homo sapiens OX=9606 GN=NUP210 PE=1 SV=3 8.8 2386.8 - 251694 - - - 0.8425 - 2.611 0.5 - 82.7 1 2 0 0.0021 25 0 0 0 2.98E+07 8.99E+06 - - - 3.8827 1 221125_WJC_METTL3_EV_vs_WT_F10.12176.12176.3 1.71E-08 16/80 R.DQQNLPYGVTPASPSGHSQGR[166.11].R "sp|Q7KZI7|MARK2_HUMAN,tr|A0A0A0MRU9|A0A0A0MRU9_HUMAN,tr|E7ETY4|E7ETY4_HUMAN,tr|A0A7I2YQF3|A0A7I2YQF3_HUMAN,tr|A0A7I2YQR3|A0A7I2YQR3_HUMAN,tr|E9PC69|E9PC69_HUMAN" 6 2205.0438 0.96 143665 12176 3 2205.040229 736.0219 Serine\threonine-protein kinase MARK2 OS=Homo sapiens OX=9606 GN=MARK2 PE=1 SV=2 6.74 2388.1 - 258506 - - - -1.6322 - 3.141 0.591 - 245.2 1 2 0 -0.0036 21 0 0 0 2.86E+07 2.98E+07 - - - 7.8721 1 221125_WJC_METTL3_EV_vs_WT_F10.12178.12178.3 5.76E-09 14/112 K.GGGSAAAAAAAAASGGAGSDNSVEHSDYR[166.11].A "sp|P40424|PBX1_HUMAN,tr|H0YLB0|H0YLB0_HUMAN,tr|H0YLF5|H0YLF5_HUMAN,tr|H0YLD4|H0YLD4_HUMAN,tr|H0YKH1|H0YKH1_HUMAN,tr|H0YLM3|H0YLM3_HUMAN,tr|F8WA05|F8WA05_HUMAN,tr|H0YLT4|H0YLT4_HUMAN,tr|A0A087X0P4|A0A087X0P4_HUMAN,tr|A0A0A0MTI0|A0A0A0MTI0_HUMAN" 10 2544.1101 1.41 143667 12178 3 2544.110083 849.044 Pre-B-cell leukemia transcription factor 1 OS=Homo sapiens OX=9606 GN=PBX1 PE=1 SV=1 4.54 2388.4 - 222935 - - - 0.0051 - 2.782 0.68 - 112.1 1 2 0 0 29 0 0 0 2.95E+06 2.09E+06 - - - 8.4753 0.9998 221125_WJC_METTL3_EV_vs_WT_F10.12179.12179.4 0.00217 Oct-78 R.LVLTQEQLHQLHSR.L "sp|Q14203|DCTN1_HUMAN,tr|A0A804CDA6|A0A804CDA6_HUMAN,tr|E7EX90|E7EX90_HUMAN,tr|A0A7P0Z4C3|A0A7P0Z4C3_HUMAN,tr|E7EWF7|E7EWF7_HUMAN" 5 1700.9322 1.69 143668 12179 4 1700.935815 426.2403 Dynactin subunit 1 OS=Homo sapiens OX=9606 GN=DCTN1 PE=1 SV=3 6.92 2388.5 - 150587 - - - 2.1241 - 1.529 0.43 - 41.6 1 2 0 0.0036 14 0 0 0 1.13E+06 6.68E+05 - - - 3.1223 0.9955 221125_WJC_METTL3_EV_vs_WT_F10.12180.12180.4 171 1/108 R.NPC[160.03]C[160.03]LC[160.03]WC[160.03]C[160.03]C[160.03]C[160.03]SC[160.03]SWNQER.R sp|P49795|RGS19_HUMAN 1 2695.9034 30.69 143669 12180 4 2695.923206 674.9831 Regulator of G-protein signaling 19 OS=Homo sapiens OX=9606 GN=RGS19 PE=1 SV=1 5.95 2388.6 - 100070 - - - 7.3467 - 0.326 0.542 - 0.3 2 2 0 0.0198 19 0 0 0 4.09E+06 1.33E+05 - - - 3.3295 1 221125_WJC_METTL3_EV_vs_WT_F10.12189.12189.3 2.02E-05 Nov-88 R.QTTAAELDSHTPALEQQTTSSEK.T "sp|Q6N021|TET2_HUMAN,tr|E7EQS8|E7EQS8_HUMAN,tr|E7EPB1|E7EPB1_HUMAN" 3 2472.1616 2.63 143676 12189 3 2472.165888 825.0611 Methylcytosine dioxygenase TET2 OS=Homo sapiens OX=9606 GN=TET2 PE=1 SV=3 4.4 2389.8 - 229070 - - - 1.7321 - 2.179 0.554 - 88.5 1 2 0 0.0043 23 0 0 0 2.60E+06 9.88E+05 - - - 6.5425 0.9999 221125_WJC_METTL3_EV_vs_WT_F10.12199.12199.3 3.60E-06 14/84 K.VDSDSSKPPETLTDPPGVC[160.03]QEK.V "sp|Q9Y520|PRC2C_HUMAN,tr|E7EPN9|E7EPN9_HUMAN,tr|H7C5N8|H7C5N8_HUMAN,tr|A0A2R8YET2|A0A2R8YET2_HUMAN" 4 2385.1006 2.47 143685 12199 3 2385.106455 796.0408 Protein PRRC2C OS=Homo sapiens OX=9606 GN=PRRC2C PE=1 SV=4 4.11 2391.2 - 478338 - - - 2.4607 - 3.01 0.509 - 105.1 1 2 0 0.0059 22 0 0 0 4.58E+07 1.85E+07 - - - 6.8257 0.9999 221125_WJC_METTL3_EV_vs_WT_F10.12201.12201.4 9.82E-07 21/126 K.TKPIVKPQTSPEYGQGINPISR.L sp|O95793|STAU1_HUMAN 1 2409.3016 2.1 143686 12201 4 2409.30836 603.3327 Double-stranded RNA-binding protein Staufen homolog 1 OS=Homo sapiens OX=9606 GN=STAU1 PE=1 SV=2 9.7 2391.4 - 2.68E+06 - - - 2.8021 - 3.418 0.525 - 222.8 1 2 0 0.0068 22 0 0 0 3.23E+08 1.53E+08 - - - 4.1959 1 221125_WJC_METTL3_EV_vs_WT_F10.12204.12204.3 6.04E-08 20/84 K.TKPIVKPQTSPEYGQGINPISR.L sp|O95793|STAU1_HUMAN 1 2409.3016 2.2 143689 12204 3 2409.306584 804.1078 Double-stranded RNA-binding protein Staufen homolog 1 OS=Homo sapiens OX=9606 GN=STAU1 PE=1 SV=2 9.7 2391.8 - 520830 - - - 2.0649 - 3.699 0.602 - 484.1 1 2 0 0.005 22 0 0 0 8.13E+07 3.69E+07 - - - 8.3515 1 221125_WJC_METTL3_EV_vs_WT_F10.12205.12205.3 8.17E-10 21/80 R.DQQNLPYGVTPASPSGHSQGR.R "sp|Q7KZI7|MARK2_HUMAN,tr|A0A0A0MRU9|A0A0A0MRU9_HUMAN,tr|E7ETY4|E7ETY4_HUMAN,tr|A0A7I2YQF3|A0A7I2YQF3_HUMAN,tr|A0A7I2YQR3|A0A7I2YQR3_HUMAN,tr|E9PC69|E9PC69_HUMAN" 6 2195.0356 0.94 143690 12205 3 2195.039353 732.6858 Serine\threonine-protein kinase MARK2 OS=Homo sapiens OX=9606 GN=MARK2 PE=1 SV=2 6.74 2392 - 466152 - - - 1.7289 - 3.51 0.557 - 435 1 2 0 0.0038 21 0 0 0 2.81E+07 2.97E+07 - - - 7.7592 0.9797 221125_WJC_METTL3_EV_vs_WT_F10.12206.12206.4 2.58E-12 21/120 R.KEDIAVNGEVEGKEEVEQETK.E "sp|P07197|NFM_HUMAN,tr|E7ESP9|E7ESP9_HUMAN" 2 2359.1391 2.18 143691 12206 4 2360.133531 590.792 Neurofilament medium polypeptide OS=Homo sapiens OX=9606 GN=NEFM PE=1 SV=3 4.22 2392.1 - 447516 - - - 421.5317 - 4.267 0.529 - 385.1 1 2 1 0.9945 21 0 0 0 2.09E+06 9.59E+05 - - - 4.0347 1 221125_WJC_METTL3_EV_vs_WT_F10.12207.12207.3 3.53E-12 16/84 K.TK[136.11]PIVK[136.11]PQTSPEYGQGINPISR[166.11].L sp|O95793|STAU1_HUMAN 1 2435.3383 2.2 143692 12207 3 2435.343275 812.7867 Double-stranded RNA-binding protein Staufen homolog 1 OS=Homo sapiens OX=9606 GN=STAU1 PE=1 SV=2 9.7 2392.2 - 368293 - - - 2.0515 - 3.235 0.714 - 254.4 1 2 0 0.005 22 0 0 0 8.13E+07 3.69E+07 - - - 9.2824 0.9999 221125_WJC_METTL3_EV_vs_WT_F10.12210.12210.3 3.60E-07 17/84 R.ESAEQSSGPGPSLRPQNSTTWR.D sp|P48634|PRC2A_HUMAN 1 2371.1153 1.21 143695 12210 3 2371.121864 791.379 Protein PRRC2A OS=Homo sapiens OX=9606 GN=PRRC2A PE=1 SV=3 6.24 2392.6 - 233481 - - - 2.7831 - 3.169 0.487 - 310.7 1 2 0 0.0066 22 0 0 0 5.72E+07 4.73E+07 - - - 6.7023 0.881 221125_WJC_METTL3_EV_vs_WT_F10.12214.12214.3 1.09E-06 13/80 R.KEDIAVNGEVEGKEEVEQETK.E "sp|P07197|NFM_HUMAN,tr|E7ESP9|E7ESP9_HUMAN" 2 2359.1391 -1 143699 12214 3 2360.127453 787.387 Neurofilament medium polypeptide OS=Homo sapiens OX=9606 GN=NEFM PE=1 SV=3 4.22 2393.1 - 150113 - - - 418.9554 - 2.895 0.534 - 163.8 1 2 1 0.9884 21 0 0 0 0.00E+00 0.00E+00 - - - 6.7683 1 221125_WJC_METTL3_EV_vs_WT_F10.12219.12219.3 4.13E-07 13/76 K.ASESSKPWPDATYGTGSASR.A "sp|Q9Y2W1|TR150_HUMAN,tr|A0A3B3ITZ9|A0A3B3ITZ9_HUMAN" 2 2053.9341 2.18 143703 12219 3 2053.935472 685.652 Thyroid hormone receptor-associated protein 3 OS=Homo sapiens OX=9606 GN=THRAP3 PE=1 SV=2 6.11 2393.7 - 336298 - - - 0.6621 - 2.88 0.575 - 144.6 1 2 0 0.0014 20 0 0 0 1.35E+07 6.19E+06 - - - 7.5165 0.9744 221125_WJC_METTL3_EV_vs_WT_F10.12220.12220.3 0.79 Jun-36 R.K[136.11]QDSGHLDLR[166.11].N "sp|Q86U44|MTA70_HUMAN,tr|B4E349|B4E349_HUMAN,tr|F5H6D8|F5H6D8_HUMAN,tr|B4DTN4|B4DTN4_HUMAN" 4 1185.6221 0.05 143704 12220 3 1185.622927 396.2146 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 6.75 2393.9 - 207168 - - - 0.6933 - 1.169 0.202 - 61.5 1 2 0 0.0008 10 0 0 0 3.84E+05 7.67E+06 - - - 1.2479 0.9999 221125_WJC_METTL3_EV_vs_WT_F10.12221.12221.4 7.56E-05 17/126 K.TK[136.11]PIVK[136.11]PQTSPEYGQGINPISR[166.11].L sp|O95793|STAU1_HUMAN 1 2435.3383 2.1 143705 12221 4 2435.344096 609.8418 Double-stranded RNA-binding protein Staufen homolog 1 OS=Homo sapiens OX=9606 GN=STAU1 PE=1 SV=2 9.7 2393.9 - 4.36E+06 - - - 2.3886 - 2.559 0.449 - 167.9 1 2 0 0.0058 22 0 0 0 3.23E+08 1.53E+08 - - - 3.4399 0.9998 221125_WJC_METTL3_EV_vs_WT_F10.12224.12224.4 0.000163 15/102 R.SESPQPAPDWGSQRPFHR.F "sp|O00165|HAX1_HUMAN,tr|E9PIQ7|E9PIQ7_HUMAN" 2 2077.9718 1.64 143708 12224 4 2077.977068 520.5002 HCLS1-associated protein X-1 OS=Homo sapiens OX=9606 GN=HAX1 PE=1 SV=2 6.47 2394.3 - 512805 - - - 2.5183 - 2.485 0.424 - 170.9 1 2 0 0.0052 18 0 0 0 6.27E+07 3.81E+07 - - - 3.2269 0.9999 221125_WJC_METTL3_EV_vs_WT_F10.12225.12225.4 1.19E-05 13/108 K.ASELGHSLNENVLKPAQEK.V "sp|Q8N6T3|ARFG1_HUMAN,tr|F8VWH9|F8VWH9_HUMAN,tr|E5RHT6|E5RHT6_HUMAN,tr|F8W1U7|F8W1U7_HUMAN,tr|E5RHC5|E5RHC5_HUMAN" 5 2063.0647 2.14 143709 12225 4 2063.070895 516.7735 ADP-ribosylation factor GTPase-activating protein 1 OS=Homo sapiens OX=9606 GN=ARFGAP1 PE=1 SV=2 5.5 2394.4 - 377948 - - - 2.9868 - 2.356 0.494 - 81.4 1 2 0 0.0062 19 0 0 0 4.71E+07 2.20E+07 - - - 3.814 1 221125_WJC_METTL3_EV_vs_WT_F10.12232.12232.4 4.23E-07 18/102 R.SESPQPAPDWGSQR[166.11]PFHR[166.11].F "sp|O00165|HAX1_HUMAN,tr|E9PIQ7|E9PIQ7_HUMAN" 2 2097.9884 1.64 143714 12232 4 2097.992218 525.5044 HCLS1-associated protein X-1 OS=Homo sapiens OX=9606 GN=HAX1 PE=1 SV=2 6.47 2395.4 - 745158 - - - 1.8318 - 2.768 0.532 - 200.5 1 2 0 0.0038 18 0 0 0 6.27E+07 3.81E+07 - - - 4.2042 0.9998 221125_WJC_METTL3_EV_vs_WT_F10.12234.12234.3 9.13E-05 14/68 R.SESPQPAPDWGSQRPFHR.F "sp|O00165|HAX1_HUMAN,tr|E9PIQ7|E9PIQ7_HUMAN" 2 2077.9718 1.67 143715 12234 3 2077.976559 693.6646 HCLS1-associated protein X-1 OS=Homo sapiens OX=9606 GN=HAX1 PE=1 SV=2 6.47 2395.6 - 357553 - - - 2.2734 - 1.998 0.45 - 160.7 1 2 0 0.0047 18 0 0 0 2.88E+07 1.73E+07 - - - 5.2793 0.9984 221125_WJC_METTL3_EV_vs_WT_F10.12235.12235.3 0.149 Oct-68 R.SESPQPAPDWGSQR[166.11]PFHR[166.11].F "sp|O00165|HAX1_HUMAN,tr|E9PIQ7|E9PIQ7_HUMAN" 2 2097.9884 1.66 143716 12235 3 2097.993731 700.3367 HCLS1-associated protein X-1 OS=Homo sapiens OX=9606 GN=HAX1 PE=1 SV=2 6.47 2395.8 - 373243 - - - 2.5529 - 1.734 0.341 - 82.9 1 2 0 0.0054 18 0 0 0 2.87E+07 1.73E+07 - - - 3.711 0.9999 221125_WJC_METTL3_EV_vs_WT_F10.12236.12236.3 1.05E-07 15/72 K.ASELGHSLNENVLKPAQEK.V "sp|Q8N6T3|ARFG1_HUMAN,tr|F8VWH9|F8VWH9_HUMAN,tr|E5RHT6|E5RHT6_HUMAN,tr|F8W1U7|F8W1U7_HUMAN,tr|E5RHC5|E5RHC5_HUMAN" 5 2063.0647 1.81 143717 12236 3 2063.07059 688.6955 ADP-ribosylation factor GTPase-activating protein 1 OS=Homo sapiens OX=9606 GN=ARFGAP1 PE=1 SV=2 5.5 2395.9 - 241325 - - - 2.839 - 2.72 0.523 - 191.1 1 2 0 0.0059 19 0 0 0 1.94E+07 1.07E+07 - - - 6.8277 0.9999 221125_WJC_METTL3_EV_vs_WT_F10.12237.12237.3 9.56E-08 15/68 K.SVEDRFDQQKNDYDQLQK.A sp|P15924|DESP_HUMAN 1 2255.0455 64.85 143718 12237 3 2255.04499 752.6891 Desmoplakin OS=Homo sapiens OX=9606 GN=DSP PE=1 SV=3 4.36 2396 - 226388 - - - -0.2058 - 3.231 0.588 - 233.3 1 2 2 -0.0005 18 0 0 0 3.49E+07 5.38E+05 - - - 8.0159 0.9999 221125_WJC_METTL3_EV_vs_WT_F10.12242.12242.4 1.83E-05 17/144 R.K[136.11]QPPVSPGTALVGSQK[136.11]EPSEVPTPK[136.11].R sp|P17096|HMGA1_HUMAN 1 2581.4178 0.92 143721 12242 4 2581.421582 646.3617 High mobility group protein HMG-I\HMG-Y OS=Homo sapiens OX=9606 GN=HMGA1 PE=1 SV=3 8.5 2396.6 - 162208 - - - 1.4775 - 3.215 0.564 - 153.2 1 2 1 0.0038 25 0 0 0 7.45E+07 8.13E+07 - - - 4.5055 0.9987 221125_WJC_METTL3_EV_vs_WT_F10.12248.12248.4 0.00055 10/102 K.SVEDRFDQQKNDYDQLQK.A sp|P15924|DESP_HUMAN 1 2255.0455 14.89 143726 12248 4 2255.04541 564.7686 Desmoplakin OS=Homo sapiens OX=9606 GN=DSP PE=1 SV=3 4.36 2397.3 - 772362 - - - -0.0195 - 2.092 0.352 - 26 1 2 2 0 18 0 0 0 5.60E+07 3.76E+06 - - - 2.5426 1 221125_WJC_METTL3_EV_vs_WT_F10.12251.12251.3 4.74E-12 16/72 R.HESGASIK[136.11]IDEPLEGSEDR[166.11].L "sp|P61978|HNRPK_HUMAN,tr|S4R359|S4R359_HUMAN" 2 2085.9934 1.34 143729 12251 3 2086.002388 696.3384 Heterogeneous nuclear ribonucleoprotein K OS=Homo sapiens OX=9606 GN=HNRNPK PE=1 SV=1 4.35 2397.7 - 190751 - - - 4.327 - 3.774 0.66 - 349.4 1 2 1 0.009 19 0 0 0 1.27E+07 9.46E+06 - - - 9.1588 0.9999 221125_WJC_METTL3_EV_vs_WT_F10.12254.12254.4 1.76E-07 17/108 K.SQPNLDTC[160.03]AFHEQPELQKK.Q "sp|P01037|CYTN_HUMAN,sp|P09228|CYTT_HUMAN,sp|P01036|CYTS_HUMAN" 3 2269.0797 113.6 143730 12254 4 2269.086326 568.2772 Cystatin-SN OS=Homo sapiens OX=9606 GN=CST1 PE=1 SV=3 5.42 2398.1 - 1.31E+06 - - - 2.9065 - 2.902 0.467 - 197.2 1 2 0 0.0066 19 0 0 0 3.93E+07 3.46E+05 - - - 3.6493 0.9999 221125_WJC_METTL3_EV_vs_WT_F10.12255.12255.4 5.90E-10 15/108 R.HESGASIK[136.11]IDEPLEGSEDR[166.11].L "sp|P61978|HNRPK_HUMAN,tr|S4R359|S4R359_HUMAN" 2 2085.9934 1.26 143731 12255 4 2085.991779 522.5056 Heterogeneous nuclear ribonucleoprotein K OS=Homo sapiens OX=9606 GN=HNRNPK PE=1 SV=1 4.35 2398.3 - 224229 - - - -0.7589 - 2.71 0.539 - 216.1 1 2 1 -0.0016 19 0 0 0 1.29E+07 1.03E+07 - - - 4.2543 1 221125_WJC_METTL3_EV_vs_WT_F10.12257.12257.3 4.12E-07 21/84 R.SGERPVTAGEEDEQVPDSIDAR.E "sp|Q9Y3D0|CIA2B_HUMAN,tr|H3BNV7|H3BNV7_HUMAN" 2 2356.0779 5.54 143733 12257 3 2356.084761 786.3666 Cytosolic iron-sulfur assembly component 2B OS=Homo sapiens OX=9606 GN=CIAO2B PE=1 SV=1 3.95 2398.5 - 235228 - - - 2.9222 - 3.828 0.593 - 358.4 1 2 0 0.0069 22 0 0 0 4.93E+06 8.89E+05 - - - 8.3319 0.983 221125_WJC_METTL3_EV_vs_WT_F10.12258.12258.3 0.00721 Dec-44 K.TRLEQEIATYRR.L "sp|Q04695|K1C17_HUMAN,sp|P02533|K1C14_HUMAN,sp|P35900|K1C20_HUMAN,sp|P08779|K1C16_HUMAN,tr|A0A3B3IS58|A0A3B3IS58_HUMAN,tr|F5GWP8|F5GWP8_HUMAN" 6 1534.8216 10.54 143734 12258 3 1534.827469 512.6145 "Keratin, type I cytoskeletal 17 OS=Homo sapiens OX=9606 GN=KRT17 PE=1 SV=2" 8.41 2398.6 - 212201 - - - 3.8311 - 2.044 0.292 - 119.2 1 2 1 0.0059 12 0 0 0 6.28E+06 5.95E+05 - - - 3.7755 1 221125_WJC_METTL3_EV_vs_WT_F10.12267.12267.3 2.16E-05 13/72 K.SQPNLDTC[160.03]AFHEQPELQKK.Q "sp|P01037|CYTN_HUMAN,sp|P09228|CYTT_HUMAN,sp|P01036|CYTS_HUMAN" 3 2269.0797 999 143740 12267 3 2269.08212 757.3672 Cystatin-SN OS=Homo sapiens OX=9606 GN=CST1 PE=1 SV=3 5.42 2399.8 - 145914 - - - 1.0528 - 2.358 0.604 - 140.9 1 2 0 0.0024 19 0 0 0 7.79E+06 0.00E+00 - - - 7.3808 0.9993 221125_WJC_METTL3_EV_vs_WT_F10.12278.12278.4 0.00143 12/168 R.GAEGILAPQPPPPQQHQERPGAAAIGSAR.G "sp|Q8WWM7|ATX2L_HUMAN,tr|H3BUF6|H3BUF6_HUMAN" 2 2900.5005 1.89 143746 12278 4 2900.505911 726.1324 Ataxin-2-like protein OS=Homo sapiens OX=9606 GN=ATXN2L PE=1 SV=2 6.76 2401.3 - 136216 - - - 1.8528 - 2.273 0.333 - 59.7 1 2 0 0.0054 29 0 0 0 1.05E+08 5.56E+07 - - - 2.376 0.9739 221125_WJC_METTL3_EV_vs_WT_F10.12279.12279.4 0.209 7/114 R.HQPGLLLQQKPPDDPVVKPK.D "sp|Q5VWN6|TASO2_HUMAN,tr|A0A2R8YH03|A0A2R8YH03_HUMAN" 2 2233.2583 2.13 143747 12279 4 2233.264073 559.3218 Protein TASOR 2 OS=Homo sapiens OX=9606 GN=TASOR2 PE=1 SV=1 8.51 2401.4 - 117300 - - - 2.5904 - 1.491 0.203 - 29.7 1 2 0 0.0058 20 0 0 0 3.76E+06 1.76E+06 - - - 1.1249 0.9996 221125_WJC_METTL3_EV_vs_WT_F10.12291.12291.3 1.67E-08 15/60 K.HNMDIGTWDNKGPVAK.A sp|Q9Y5A9|YTHD2_HUMAN 1 1781.8519 1.28 143754 12291 3 1781.858134 594.9579 YTH domain-containing family protein 2 OS=Homo sapiens OX=9606 GN=YTHDF2 PE=1 SV=2 6.75 2403 - 502674 - - - 3.4969 - 2.907 0.561 - 277.7 1 2 1 0.0062 16 0 0 0 2.69E+07 2.11E+07 - - - 7.531 0.7778 221125_WJC_METTL3_EV_vs_WT_F10.12292.12292.3 0.141 Apr-96 R.EKHC[160.03]VFDAATENGTANGVPPMATK[136.11]K[136.11].A "sp|Q2M1K9|ZN423_HUMAN,tr|F5H7S1|F5H7S1_HUMAN,tr|A0A7P0Q1F0|A0A7P0Q1F0_HUMAN" 3 2688.2971 - 143755 12292 3 2688.295843 897.1063 Zinc finger protein 423 OS=Homo sapiens OX=9606 GN=ZNF423 PE=1 SV=1 6.84 2403.2 - 166321 - - - -0.4568 - 1.055 0.201 - 10.5 2 2 1 -0.0012 25 0 0 0 - - - - - 0.7645 0.9994 221125_WJC_METTL3_EV_vs_WT_F10.12304.12304.3 0.000107 Aug-92 R.SSEDLAGPLPSSVSSSSTTSSKPK.L sp|Q9NRF2|SH2B1_HUMAN 1 2335.1391 0.92 143761 12304 3 2335.145767 779.387 SH2B adapter protein 1 OS=Homo sapiens OX=9606 GN=SH2B1 PE=1 SV=3 5.79 2404.7 - 93725.2 - - - 2.8641 - 1.922 0.419 - 49.6 1 2 0 0.0067 24 0 0 0 2.12E+06 2.30E+06 - - - 4.7271 0.9998 221125_WJC_METTL3_EV_vs_WT_F10.12306.12306.4 2.15E-11 27/144 R.KQPPVSPGTALVGSQKEPSEVPTPK.R sp|P17096|HMGA1_HUMAN 1 2557.3752 0.92 143762 12306 4 2557.381833 640.3511 High mobility group protein HMG-I\HMG-Y OS=Homo sapiens OX=9606 GN=HMGA1 PE=1 SV=3 8.5 2405 - 677289 - - - 2.6062 - 4.627 0.553 - 446.5 1 2 1 0.0067 25 0 0 0 7.45E+07 8.13E+07 - - - 4.5248 0.9829 221125_WJC_METTL3_EV_vs_WT_F10.12307.12307.4 0.0082 11/138 R.SVEEIAPDPSEAKRPEPPSTSTLK.Q "sp|Q9NS91|RAD18_HUMAN,tr|F8WE49|F8WE49_HUMAN" 2 2564.297 1.34 143763 12307 4 2564.306204 642.0815 E3 ubiquitin-protein ligase RAD18 OS=Homo sapiens OX=9606 GN=RAD18 PE=1 SV=2 4.58 2405.1 - 143624 - - - 3.5983 - 1.864 0.307 - 62.8 1 2 1 0.0092 24 0 0 0 5.84E+06 4.36E+06 - - - 2.0954 0.9989 221125_WJC_METTL3_EV_vs_WT_F10.12315.12315.3 1.64E-05 Dec-60 K.HNMDIGTWDNK[136.11]GPVAK[136.11].A sp|Q9Y5A9|YTHD2_HUMAN 1 1797.8803 1.28 143768 12315 3 1797.88535 600.3007 YTH domain-containing family protein 2 OS=Homo sapiens OX=9606 GN=YTHDF2 PE=1 SV=2 6.75 2406.2 - 838680 - - - 2.8072 - 2.199 0.443 - 158.1 1 2 1 0.005 16 0 0 0 2.69E+07 2.11E+07 - - - 5.4995 0.916 221125_WJC_METTL3_EV_vs_WT_F10.12317.12317.4 0.64 10/108 K.SPVLPSGHHLQIPAHAEVK.S sp|Q5T3J3|LRIF1_HUMAN 1 2016.0905 1.69 143770 12317 4 2016.096716 505.0299 Ligand-dependent nuclear receptor-interacting factor 1 OS=Homo sapiens OX=9606 GN=LRIF1 PE=1 SV=1 6.78 2406.4 - 229704 - - - 3.0862 - 1.642 0.165 - 35.5 1 2 0 0.0062 19 0 0 0 2.04E+07 1.21E+07 - - - 0.8282 0.9841 221125_WJC_METTL3_EV_vs_WT_F10.12324.12324.4 0.00561 12/138 R.SVEEIAPDPSEAK[136.11]R[166.11]PEPPSTSTLK[136.11].Q "sp|Q9NS91|RAD18_HUMAN,tr|F8WE49|F8WE49_HUMAN" 2 2590.3336 1.35 143775 12324 4 2590.341131 648.5907 E3 ubiquitin-protein ligase RAD18 OS=Homo sapiens OX=9606 GN=RAD18 PE=1 SV=2 4.58 2407.4 - 172653 - - - 2.8892 - 1.906 0.285 - 46.3 1 2 1 0.0075 24 0 0 0 5.84E+06 4.32E+06 - - - 1.9116 0.9998 221125_WJC_METTL3_EV_vs_WT_F10.12327.12327.4 3.07E-06 15/102 K.STWSPDPIGHNPTHLSNK.M "sp|Q9UPQ9|TNR6B_HUMAN,tr|H0Y720|H0Y720_HUMAN" 2 1986.9548 2.67 143776 12327 4 1986.962447 497.746 Trinucleotide repeat-containing gene 6B protein OS=Homo sapiens OX=9606 GN=TNRC6B PE=1 SV=4 6.66 2407.8 - 333978 - - - 3.8546 - 2.57 0.515 - 140 1 2 0 0.0077 18 0 0 0 2.37E+07 8.86E+06 - - - 4.0298 0.9997 221125_WJC_METTL3_EV_vs_WT_F10.12328.12328.4 1.97E-06 18/90 R.SK[136.11]VDEAVAVLQAHHAK[136.11].K "sp|Q13310|PABP4_HUMAN,tr|A0A7I2V5W9|A0A7I2V5W9_HUMAN,tr|H0YEU6|H0YEU6_HUMAN,tr|B1ANR0|B1ANR0_HUMAN,tr|A0A7I2V4L7|A0A7I2V4L7_HUMAN,tr|H0YER0|H0YER0_HUMAN,tr|A0A7I2V598|A0A7I2V598_HUMAN,tr|A0A7I2V4V6|A0A7I2V4V6_HUMAN,tr|H0Y5F5|H0Y5F5_HUMAN,tr|H0Y6X6|H0Y6X6_HUMAN" 10 1717.9446 1.41 143777 12328 4 1717.950074 430.4934 Polyadenylate-binding protein 4 OS=Homo sapiens OX=9606 GN=PABPC4 PE=1 SV=1 6.66 2408 - 293584 - - - 3.1759 - 3.099 0.554 - 371.3 1 2 1 0.0055 16 0 0 0 1.19E+08 8.43E+07 - - - 4.4449 0.9999 221125_WJC_METTL3_EV_vs_WT_F10.12329.12329.4 1.43E-05 17/168 R.GAEGILAPQPPPPQQHQER[166.11]PGAAAIGSAR[166.11].G "sp|Q8WWM7|ATX2L_HUMAN,tr|H3BUF6|H3BUF6_HUMAN" 2 2920.5171 1.89 143778 12329 4 2920.525799 731.1365 Ataxin-2-like protein OS=Homo sapiens OX=9606 GN=ATXN2L PE=1 SV=2 6.76 2408.1 - 155621 - - - 2.9865 - 3.131 0.52 - 119.7 1 2 0 0.0087 29 0 0 0 1.05E+08 5.56E+07 - - - 4.1014 1 221125_WJC_METTL3_EV_vs_WT_F10.12337.12337.4 1.23E-07 12/132 R.DYGPGSYGGMDR[166.11]DYGHGSYGGQR[166.11].S "sp|Q5BKZ1|ZN326_HUMAN,tr|A0A0A0MRN4|A0A0A0MRN4_HUMAN" 2 2471.01 1.31 143784 12337 4 2471.023613 618.7598 DBIRD complex subunit ZNF326 OS=Homo sapiens OX=9606 GN=ZNF326 PE=1 SV=2 5.3 2409.2 - 108048 - - - 5.5192 - 2.5 0.693 - 54.4 1 2 1 0.0136 23 0 0 0 6.19E+06 4.71E+06 - - - 5.551 0.9991 221125_WJC_METTL3_EV_vs_WT_F10.12342.12342.3 1.49E-09 19/60 R.SK[136.11]VDEAVAVLQAHHAK[136.11].K "sp|Q13310|PABP4_HUMAN,tr|A0A7I2V5W9|A0A7I2V5W9_HUMAN,tr|H0YEU6|H0YEU6_HUMAN,tr|B1ANR0|B1ANR0_HUMAN,tr|A0A7I2V4L7|A0A7I2V4L7_HUMAN,tr|H0YER0|H0YER0_HUMAN,tr|A0A7I2V598|A0A7I2V598_HUMAN,tr|A0A7I2V4V6|A0A7I2V4V6_HUMAN,tr|H0Y5F5|H0Y5F5_HUMAN,tr|H0Y6X6|H0Y6X6_HUMAN" 10 1717.9446 1.33 143787 12342 3 1717.953813 573.6555 Polyadenylate-binding protein 4 OS=Homo sapiens OX=9606 GN=PABPC4 PE=1 SV=1 6.66 2409.9 - 328809 - - - 5.3523 - 3.553 0.592 - 388.8 1 2 1 0.0092 16 0 0 0 3.54E+07 2.66E+07 - - - 8.3907 0.9922 221125_WJC_METTL3_EV_vs_WT_F10.12344.12344.4 0.00176 12/120 K.GIHHGPSVAQPIHLDSTQLSR.K sp|Q8NBT2|SPC24_HUMAN 1 2249.1665 3.23 143789 12344 4 2249.178143 563.2989 Kinetochore protein Spc24 OS=Homo sapiens OX=9606 GN=SPC24 PE=1 SV=2 7.02 2410.1 - 198867 - - - 5.1712 - 2.411 0.325 - 81.4 1 2 0 0.0116 21 0 0 0 7.28E+06 2.25E+06 - - - 2.3426 0.9999 221125_WJC_METTL3_EV_vs_WT_F10.12358.12358.3 3.90E-07 14/68 K.STWSPDPIGHNPTHLSNK.M "sp|Q9UPQ9|TNR6B_HUMAN,tr|H0Y720|H0Y720_HUMAN" 2 1986.9548 2.47 143798 12358 3 1986.961096 663.3255 Trinucleotide repeat-containing gene 6B protein OS=Homo sapiens OX=9606 GN=TNRC6B PE=1 SV=4 6.66 2412.1 - 394447 - - - 3.1747 - 2.873 0.609 - 169.9 1 2 0 0.0063 18 0 0 0 1.14E+07 4.61E+06 - - - 7.9559 0.9285 221125_WJC_METTL3_EV_vs_WT_F10.12366.12366.2 0.0172 18-Oct A.VAVLQAHHAK.K "sp|Q13310|PABP4_HUMAN,tr|A0A7I2V5W9|A0A7I2V5W9_HUMAN,tr|H0YEU6|H0YEU6_HUMAN,tr|B1ANR0|B1ANR0_HUMAN,tr|A0A7I2V4L7|A0A7I2V4L7_HUMAN,tr|H0YER0|H0YER0_HUMAN,tr|A0A7I2V598|A0A7I2V598_HUMAN,tr|A0A7I2V4V6|A0A7I2V4V6_HUMAN,tr|H0Y5F5|H0Y5F5_HUMAN,tr|H0Y6X6|H0Y6X6_HUMAN" 10 1072.6142 1.2 143802 12366 2 1072.61708 537.3144 Polyadenylate-binding protein 4 OS=Homo sapiens OX=9606 GN=PABPC4 PE=1 SV=1 8.74 2413.2 - 85306.5 - - - 2.7205 - 1.923 0.348 - 331.2 1 1 0 0.0029 10 0 0 0 1.69E+06 1.42E+06 - - - 3.4356 1 221125_WJC_METTL3_EV_vs_WT_F10.12369.12369.4 3.71E-09 18/90 K.ELEDAYWK[136.11]DDDK[136.11]HVMR[166.11].K "sp|Q96CT7|CC124_HUMAN,tr|M0R2F5|M0R2F5_HUMAN" 2 2074.9629 0.06 143804 12369 4 2074.970589 519.748 Coiled-coil domain-containing protein 124 OS=Homo sapiens OX=9606 GN=CCDC124 PE=1 SV=1 4.52 2413.6 - 258162 - - - 3.7249 - 3.295 0.662 - 215.9 1 2 2 0.0077 16 0 0 0 3.90E+06 6.71E+07 - - - 5.4059 0.9998 221125_WJC_METTL3_EV_vs_WT_F10.12374.12374.3 5.63E-05 Dec-68 K.STWSPDPIGHNPTHLSNK[136.11].M "sp|Q9UPQ9|TNR6B_HUMAN,tr|H0Y720|H0Y720_HUMAN" 2 1994.969 2.45 143807 12374 3 1994.972163 665.9969 Trinucleotide repeat-containing gene 6B protein OS=Homo sapiens OX=9606 GN=TNRC6B PE=1 SV=4 6.66 2414.3 - 229465 - - - 1.5915 - 2.11 0.397 - 118 1 2 0 0.0032 18 0 0 0 1.14E+07 4.65E+06 - - - 4.8246 1 221125_WJC_METTL3_EV_vs_WT_F10.12376.12376.3 1.08E-08 16/68 K.NQDEC[160.03]VIALHDC[160.03]NGDVNR[166.11].A "sp|Q14157|UBP2L_HUMAN,tr|Q5VU78|Q5VU78_HUMAN,tr|F8W726|F8W726_HUMAN,tr|Q5VU81|Q5VU81_HUMAN,tr|Q5VU79|Q5VU79_HUMAN,tr|Q5VU80|Q5VU80_HUMAN,tr|Q5VU77|Q5VU77_HUMAN" 7 2137.9145 2.43 143809 12376 3 2138.923578 713.6454 Ubiquitin-associated protein 2-like OS=Homo sapiens OX=9606 GN=UBAP2L PE=1 SV=2 4.22 2414.6 - 251320 - - - 472.0058 - 3.445 0.665 - 453.4 1 2 0 1.0091 18 0 0 0 1.39E+07 5.74E+06 - - - 8.7546 0.9996 221125_WJC_METTL3_EV_vs_WT_F10.12377.12377.4 0.000165 13/126 R.EK[136.11]ESAC[160.03]ALSGADEQPPFHPEPR[166.11].K sp|P17509|HXB6_HUMAN 1 2469.135 2.44 143810 12377 4 2469.141316 618.291 Homeobox protein Hox-B6 OS=Homo sapiens OX=9606 GN=HOXB6 PE=1 SV=4 4.57 2414.7 - 221369 - - - 2.575 - 2.46 0.49 - 95 1 2 1 0.0064 22 0 0 0 3.30E+07 1.35E+07 - - - 3.7837 0.9542 221125_WJC_METTL3_EV_vs_WT_F10.12380.12380.2 4.19E-05 24-Sep A.VPELATDPELEK[136.11]K[136.11].L "sp|Q86U44|MTA70_HUMAN,tr|B4E349|B4E349_HUMAN,tr|F5H6D8|F5H6D8_HUMAN,tr|H0YFV6|H0YFV6_HUMAN,tr|B4DTN4|B4DTN4_HUMAN" 5 1483.8105 0.12 143813 12380 2 1483.815008 742.9125 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 4.41 2415.1 - 94242.1 - - - 3.055 - 1.982 0.479 - 205.1 1 1 0 0.0045 13 0 0 0 3.26E+05 2.82E+06 - - - 4.3332 0.9997 221125_WJC_METTL3_EV_vs_WT_F10.12385.12385.4 1.04E-07 21/126 R.EKESAC[160.03]ALSGADEQPPFHPEPR.K sp|P17509|HXB6_HUMAN 1 2451.1125 2.42 143816 12385 4 2451.120763 613.7854 Homeobox protein Hox-B6 OS=Homo sapiens OX=9606 GN=HOXB6 PE=1 SV=4 4.57 2415.8 - 638046 - - - 3.376 - 3.868 0.552 - 240.8 1 2 1 0.0083 22 0 0 0 3.30E+07 1.36E+07 - - - 4.4709 0.9986 221125_WJC_METTL3_EV_vs_WT_F10.12395.12395.3 0.361 Jun-80 K.QKPAQNYDDNFNVNGPGEGVK.V "sp|Q5F1R6|DJC21_HUMAN,tr|A0A2R8Y534|A0A2R8Y534_HUMAN" 2 2290.0614 0.69 143824 12395 3 2290.061782 764.3611 DnaJ homolog subfamily C member 21 OS=Homo sapiens OX=9606 GN=DNAJC21 PE=1 SV=2 4.56 2417.1 - 140066 - - - 0.1502 - 1.308 0.348 - 39.2 1 2 0 0.0003 21 0 0 0 5.66E+06 8.19E+06 - - - 3.0635 0.9995 221125_WJC_METTL3_EV_vs_WT_F10.12400.12400.2 0.0024 22-Sep R.ALEESNYELEGK.L "sp|P13645|K1C10_HUMAN,tr|A0A1B0GVI3|A0A1B0GVI3_HUMAN" 2 1380.6409 68.35 143827 12400 2 1380.643978 691.3277 "Keratin, type I cytoskeletal 10 OS=Homo sapiens OX=9606 GN=KRT10 PE=1 SV=6" 4.09 2417.8 - 304979 - - - 2.2366 - 2.095 0.436 - 171.7 1 2 0 0.0031 12 0 0 0 1.07E+07 1.56E+05 - - - 4.2062 0.9998 221125_WJC_METTL3_EV_vs_WT_F10.12401.12401.3 8.77E-05 Nov-52 K.K[136.11]HPDSSVNFAEFSK[136.11].K "sp|P26583|HMGB2_HUMAN,tr|D6R9A6|D6R9A6_HUMAN" 2 1607.7915 0.21 143828 12401 3 1607.794615 536.9378 High mobility group protein B2 OS=Homo sapiens OX=9606 GN=HMGB2 PE=1 SV=2 6.75 2418 - 285289 - - - 1.9555 - 2.388 0.386 - 177.6 1 2 0 0.0031 14 0 0 0 6.11E+06 2.95E+07 - - - 5.1559 0.9999 221125_WJC_METTL3_EV_vs_WT_F10.12402.12402.3 7.48E-06 Oct-84 R.EKESAC[160.03]ALSGADEQPPFHPEPR.K sp|P17509|HXB6_HUMAN 1 2451.1125 2.46 143829 12402 3 2451.11414 818.0448 Homeobox protein Hox-B6 OS=Homo sapiens OX=9606 GN=HOXB6 PE=1 SV=4 4.57 2418.1 - 160638 - - - 0.674 - 2.782 0.636 - 84.8 1 2 1 0.0017 22 0 0 0 5.24E+06 2.13E+06 - - - 8.0561 0.9985 221125_WJC_METTL3_EV_vs_WT_F10.12406.12406.3 1.01E-08 20/48 A.VPELATDPELEK[136.11]K[136.11].L "sp|Q86U44|MTA70_HUMAN,tr|B4E349|B4E349_HUMAN,tr|F5H6D8|F5H6D8_HUMAN,tr|H0YFV6|H0YFV6_HUMAN,tr|B4DTN4|B4DTN4_HUMAN" 5 1483.8105 0.02 143831 12406 3 1483.81267 495.6108 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 4.41 2418.6 - 3.29E+06 - - - 1.4793 - 3.196 0.591 - 664 1 1 0 0.0022 13 0 0 0 1.14E+06 7.60E+07 - - - 8.2787 0.9879 221125_WJC_METTL3_EV_vs_WT_F10.12410.12410.2 0.0354 16-Jun R.SLVNLGGSK.S sp|P04264|K2C1_HUMAN 1 873.492 999 143835 12410 2 873.493953 437.7533 "Keratin, type II cytoskeletal 1 OS=Homo sapiens OX=9606 GN=KRT1 PE=1 SV=6" 8.47 2419.2 - 238573 - - - 2.2565 - 1.198 0.22 - 96.6 1 2 0 0.002 9 0 0 0 5.61E+06 0.00E+00 - - - 1.1879 0.9998 221125_WJC_METTL3_EV_vs_WT_F10.12413.12413.4 1.50E-09 21/90 R.SKVDEAVAVLQAHHAK.K "sp|Q13310|PABP4_HUMAN,tr|A0A7I2V5W9|A0A7I2V5W9_HUMAN,tr|H0YEU6|H0YEU6_HUMAN,tr|B1ANR0|B1ANR0_HUMAN,tr|A0A7I2V4L7|A0A7I2V4L7_HUMAN,tr|H0YER0|H0YER0_HUMAN,tr|A0A7I2V598|A0A7I2V598_HUMAN,tr|A0A7I2V4V6|A0A7I2V4V6_HUMAN,tr|H0Y5F5|H0Y5F5_HUMAN,tr|H0Y6X6|H0Y6X6_HUMAN" 10 1701.9162 1.41 143837 12413 4 1701.920211 426.4863 Polyadenylate-binding protein 4 OS=Homo sapiens OX=9606 GN=PABPC4 PE=1 SV=1 6.66 2419.5 - 2.72E+06 - - - 2.3462 - 3.262 0.517 - 439.2 1 2 1 0.004 16 0 0 0 1.19E+08 8.43E+07 - - - 4.1414 0.9999 221125_WJC_METTL3_EV_vs_WT_F10.12419.12419.3 9.29E-06 Nov-84 R.EK[136.11]ESAC[160.03]ALSGADEQPPFHPEPR[166.11].K sp|P17509|HXB6_HUMAN 1 2469.135 2.46 143842 12419 3 2469.134959 824.0523 Homeobox protein Hox-B6 OS=Homo sapiens OX=9606 GN=HOXB6 PE=1 SV=4 4.57 2420.3 - 151933 - - - 0.0004 - 2.391 0.535 - 111.5 1 2 1 0 22 0 0 0 5.24E+06 2.13E+06 - - - 6.5714 1 221125_WJC_METTL3_EV_vs_WT_F10.12425.12425.3 1.60E-05 18/76 R.DDIIENAPTTHTEEYSGEEK.T "sp|O14744|ANM5_HUMAN,tr|G3V580|G3V580_HUMAN,tr|G3V2X6|G3V2X6_HUMAN,tr|G3V5L5|G3V5L5_HUMAN,tr|H0YJX6|H0YJX6_HUMAN" 5 2276.9921 2.01 143846 12425 3 2277.001307 760.0046 Protein arginine N-methyltransferase 5 OS=Homo sapiens OX=9606 GN=PRMT5 PE=1 SV=4 4 2421.1 - 215615 - - - 4.0518 - 3.565 0.63 - 408 1 2 0 0.0092 20 0 0 0 1.43E+07 7.10E+06 - - - 8.6452 0.9999 221125_WJC_METTL3_EV_vs_WT_F10.12429.12429.3 0.00224 Aug-52 K.KHPDSSVNFAEFSK.K "sp|P26583|HMGB2_HUMAN,tr|D6R9A6|D6R9A6_HUMAN" 2 1591.7631 0.21 143848 12429 3 1591.765779 531.595 High mobility group protein B2 OS=Homo sapiens OX=9606 GN=HMGB2 PE=1 SV=2 6.75 2421.7 - 290838 - - - 1.7013 - 2.107 0.436 - 81.9 1 2 0 0.0027 14 0 0 0 6.07E+06 2.94E+07 - - - 5.3808 0.8904 221125_WJC_METTL3_EV_vs_WT_F10.12431.12431.4 1.5 9/144 R.ASPGHSPHYFAASSPTSPNALPPAR.K sp|Q8TEM1|PO210_HUMAN 1 2516.2197 2.53 143850 12431 4 2516.220736 630.0622 Nuclear pore membrane glycoprotein 210 OS=Homo sapiens OX=9606 GN=NUP210 PE=1 SV=3 8.8 2421.9 - 160791 - - - 0.4237 - 1.581 0.113 - 24.8 1 2 0 0.0011 25 0 0 0 2.47E+06 9.76E+05 - - - 0.355 0.9997 221125_WJC_METTL3_EV_vs_WT_F10.12436.12436.4 8.50E-08 14/96 R.YTC[160.03]HVQHEGLPKPLTLR.W "sp|P01889|HLAB_HUMAN,sp|P04439|HLAA_HUMAN,tr|A0A140T941|A0A140T941_HUMAN,tr|A0A1W2PQS8|A0A1W2PQS8_HUMAN,tr|A0A0G2JI36|A0A0G2JI36_HUMAN,tr|A0A140T8W8|A0A140T8W8_HUMAN,tr|A0A140T951|A0A140T951_HUMAN,tr|Q9GJ45|Q9GJ45_HUMAN,tr|Q53Z42|Q53Z42_HUMAN,tr|Q5RJ27|Q5RJ27_HUMAN,tr|Q5SRN5|Q5SRN5_HUMAN,tr|A0A1W2PS24|A0A1W2PS24_HUMAN,tr|A0A0G2JIF2|A0A0G2JIF2_HUMAN,tr|Q2L6G2|Q2L6G2_HUMAN,tr|A0A1W2PQD0|A0A1W2PQD0_HUMAN,tr|A0A140T955|A0A140T955_HUMAN,tr|A0A0G2JPD3|A0A0G2JPD3_HUMAN,tr|D5H3J5|D5H3J5_HUMAN,tr|S6AU73|S6AU73_HUMAN,tr|A0A140T913|A0A140T913_HUMAN,tr|A0A1W2PPQ2|A0A1W2PPQ2_HUMAN,tr|A0A1W2PQE2|A0A1W2PQE2_HUMAN,tr|Q5SPM2|Q5SPM2_HUMAN,tr|A0A1W2PQZ3|A0A1W2PQZ3_HUMAN,tr|Q5SUL5|Q5SUL5_HUMAN,tr|A0A140T8Y4|A0A140T8Y4_HUMAN,tr|A0A140T975|A0A140T975_HUMAN,tr|A0A1W2PP29|A0A1W2PP29_HUMAN,tr|A0A140T933|A0A140T933_HUMAN,tr|A0A1W2PSE7|A0A1W2PSE7_HUMAN,tr|A0A1W2PRT9|A0A1W2PRT9_HUMAN,tr|A0A140T9G0|A0A140T9G0_HUMAN,tr|A0A140T9H3|A0A140T9H3_HUMAN,tr|A0A1W2PPF8|A0A1W2PPF8_HUMAN,tr|Q5SS57|Q5SS57_HUMAN,tr|D9J307|D9J307_HUMAN,tr|A0A140T9A9|A0A140T9A9_HUMAN,tr|Q5SRN7|Q5SRN7_HUMAN,tr|A0A1W2PR61|A0A1W2PR61_HUMAN,tr|A0A140T9I0|A0A140T9I0_HUMAN,tr|A0A140T9S9|A0A140T9S9_HUMAN,tr|A0A140T9X5|A0A140T9X5_HUMAN,tr|A0A1W2PS39|A0A1W2PS39_HUMAN,tr|A0A140T9Z6|A0A140T9Z6_HUMAN,tr|B0UXQ0|B0UXQ0_HUMAN,tr|A0A0G2JL56|A0A0G2JL56_HUMAN" 46 2048.0626 0.47 143852 12436 4 2048.073004 513.0229 "HLA class I histocompatibility antigen, B alpha chain OS=Homo sapiens OX=9606 GN=HLA-B PE=1 SV=3" 8.22 2422.6 - 232195 - - - 5.097 - 2.331 0.577 - 113.2 1 2 0 0.0104 17 0 0 0 8.22E+06 1.74E+07 - - - 4.5391 0.9966 221125_WJC_METTL3_EV_vs_WT_F10.12437.12437.4 0.014 Sep-78 K.K[136.11]HPDSSVNFAEFSK[136.11].K "sp|P26583|HMGB2_HUMAN,tr|D6R9A6|D6R9A6_HUMAN" 2 1607.7915 0.29 143853 12437 4 1607.796023 402.9551 High mobility group protein B2 OS=Homo sapiens OX=9606 GN=HMGB2 PE=1 SV=2 6.75 2422.7 - 201992 - - - 2.8312 - 1.547 0.297 - 50 1 2 0 0.0046 14 0 0 0 9.96E+05 3.47E+06 - - - 1.9686 0.9999 221125_WJC_METTL3_EV_vs_WT_F10.12438.12438.4 1.03E-05 10/150 K.APSATSPSGQLPHHSSTQPLDLAPGR[166.11].M sp|P0C7T5|ATX1L_HUMAN 1 2618.3076 2.84 143854 12438 4 2618.313342 655.5842 Ataxin-1-like OS=Homo sapiens OX=9606 GN=ATXN1L PE=1 SV=1 6.96 2422.8 - 198089 - - - 2.1751 - 2.6 0.443 - 47.7 1 2 0 0.0057 26 0 0 0 1.75E+07 6.18E+06 - - - 3.3817 0.9994 221125_WJC_METTL3_EV_vs_WT_F10.12443.12443.3 0.000631 11/112 R.GAEGILAPQPPPPQQHQERPGAAAIGSAR.G "sp|Q8WWM7|ATX2L_HUMAN,tr|H3BUF6|H3BUF6_HUMAN" 2 2900.5005 2.46 143857 12443 3 2900.509641 967.8408 Ataxin-2-like protein OS=Homo sapiens OX=9606 GN=ATXN2L PE=1 SV=2 6.76 2423.5 - 136265 - - - 3.1388 - 1.935 0.438 - 67.1 1 2 0 0.0091 29 0 0 0 4.59E+06 1.87E+06 - - - 4.9394 0.9979 221125_WJC_METTL3_EV_vs_WT_F10.12444.12444.3 0.00803 8/112 R.GAEGILAPQPPPPQQHQER[166.11]PGAAAIGSAR[166.11].G "sp|Q8WWM7|ATX2L_HUMAN,tr|H3BUF6|H3BUF6_HUMAN" 2 2920.5171 2.46 143858 12444 3 2920.524367 974.513 Ataxin-2-like protein OS=Homo sapiens OX=9606 GN=ATXN2L PE=1 SV=2 6.76 2423.7 - 74740.5 - - - 2.4961 - 1.456 0.367 - 26.9 1 2 0 0.0073 29 0 0 0 4.59E+06 1.87E+06 - - - 3.494 0.9999 221125_WJC_METTL3_EV_vs_WT_F10.12452.12452.4 3.96E-05 11/102 R.SHTGER[166.11]PFQC[160.03]SLC[160.03]SYASR[166.11].D "sp|P49711|CTCF_HUMAN,tr|A0A2R8YFL0|A0A2R8YFL0_HUMAN,tr|A0A2R8Y595|A0A2R8Y595_HUMAN" 3 2161.9536 1.06 143863 12452 4 2161.960348 541.4957 Transcriptional repressor CTCF OS=Homo sapiens OX=9606 GN=CTCF PE=1 SV=1 7.82 2424.7 - 130824 - - - 3.0995 - 2.005 0.49 - 99.3 1 2 0 0.0067 18 0 0 0 3.08E+06 2.90E+06 - - - 3.7274 0.9918 221125_WJC_METTL3_EV_vs_WT_F10.12453.12453.4 0.098 Sep-90 R.SGK[136.11]YDLDFK[136.11]SPDDPSR[166.11].Y "sp|P06733|ENOA_HUMAN,tr|A0A2R8Y6G6|A0A2R8Y6G6_HUMAN" 2 1851.8849 1.53 143864 12453 4 1851.88852 463.9785 Alpha-enolase OS=Homo sapiens OX=9606 GN=ENO1 PE=1 SV=2 4.58 2424.9 - 112178 - - - 1.9402 - 2.084 0.28 - 53.7 1 2 2 0.0036 16 0 0 0 5.29E+07 3.46E+07 - - - 1.9208 0.9631 221125_WJC_METTL3_EV_vs_WT_F10.12460.12460.3 4.37E-05 Oct-88 K.HGSYGPAEYDYGHTGYGPSGGSR.K sp|Q5D862|FILA2_HUMAN 1 2370.989 2.52 143869 12460 3 2371.975646 791.3369 Filaggrin-2 OS=Homo sapiens OX=9606 GN=FLG2 PE=1 SV=1 5.99 2426 - 149377 - - - 416.1318 - 2.263 0.615 - 99.5 1 2 0 0.9866 23 0 0 0 2.20E+06 8.72E+05 - - - 7.0393 0.9998 221125_WJC_METTL3_EV_vs_WT_F10.12461.12461.3 3.99E-08 14/84 K.HGAPSPSHPISAPQAAAAAALR.R "sp|P35658|NU214_HUMAN,tr|A0A0A0MSW3|A0A0A0MSW3_HUMAN,tr|H0YF36|H0YF36_HUMAN,tr|A0A494C1F2|A0A494C1F2_HUMAN" 4 2077.0817 3.6 143870 12461 3 2077.091464 693.3678 Nuclear pore complex protein Nup214 OS=Homo sapiens OX=9606 GN=NUP214 PE=1 SV=2 9.76 2426.1 - 119852 - - - 4.6912 - 2.765 0.565 - 142.6 1 2 0 0.0097 22 0 0 0 7.46E+06 2.07E+06 - - - 7.2477 1 221125_WJC_METTL3_EV_vs_WT_F10.12465.12465.4 2.35E-10 17/126 K.HGAPSPSHPISAPQAAAAAALR[166.11].R "sp|P35658|NU214_HUMAN,tr|A0A0A0MSW3|A0A0A0MSW3_HUMAN,tr|H0YF36|H0YF36_HUMAN,tr|A0A494C1F2|A0A494C1F2_HUMAN" 4 2087.09 2.98 143872 12465 4 2087.09387 522.7798 Nuclear pore complex protein Nup214 OS=Homo sapiens OX=9606 GN=NUP214 PE=1 SV=2 9.76 2426.6 - 130719 - - - 1.859 - 3.47 0.557 - 229.6 1 2 0 0.0039 22 0 0 0 1.59E+07 5.31E+06 - - - 4.4801 0.9994 221125_WJC_METTL3_EV_vs_WT_F10.12466.12466.4 0.00876 14/150 K.APSATSPSGQLPHHSSTQPLDLAPGR.M sp|P0C7T5|ATX1L_HUMAN 1 2608.2994 3.22 143873 12466 4 2608.307965 653.0821 Ataxin-1-like OS=Homo sapiens OX=9606 GN=ATXN1L PE=1 SV=1 6.96 2426.8 - 567677 - - - 3.2926 - 2.091 0.397 - 78 1 2 0 0.0086 26 0 0 0 1.99E+07 6.18E+06 - - - 2.9118 0.9983 221125_WJC_METTL3_EV_vs_WT_F10.12467.12467.4 9.09E-05 16/90 R.SGKYDLDFKSPDDPSR.Y "sp|P06733|ENOA_HUMAN,tr|A0A2R8Y6G6|A0A2R8Y6G6_HUMAN" 2 1825.8483 1.52 143874 12467 4 1825.853931 457.4693 Alpha-enolase OS=Homo sapiens OX=9606 GN=ENO1 PE=1 SV=2 4.58 2426.9 - 383764 - - - 3.1076 - 2.38 0.406 - 198.1 1 2 2 0.0057 16 0 0 0 5.27E+07 3.46E+07 - - - 3.0637 0.9998 221125_WJC_METTL3_EV_vs_WT_F10.12471.12471.4 1.77E-11 27/144 R.K[136.11]QPPVSPGTALVGSQK[136.11]EPSEVPTPK[136.11].R sp|P17096|HMGA1_HUMAN 1 2581.4178 0.92 143877 12471 4 2581.426371 646.3617 High mobility group protein HMG-I\HMG-Y OS=Homo sapiens OX=9606 GN=HMGA1 PE=1 SV=3 8.5 2427.4 - 732978 - - - 3.3327 - 4.48 0.601 - 388 1 2 1 0.0086 25 0 0 0 7.45E+07 8.13E+07 - - - 4.9318 0.9995 221125_WJC_METTL3_EV_vs_WT_F10.12476.12476.2 0.000222 Jul-32 R.TDYNASVSVPDSSGPER[166.11].L "sp|P61978|HNRPK_HUMAN,tr|Q5T6W2|Q5T6W2_HUMAN" 2 1789.7994 1.53 143880 12476 2 1789.803787 895.907 Heterogeneous nuclear ribonucleoprotein K OS=Homo sapiens OX=9606 GN=HNRNPK PE=1 SV=1 4.03 2428 - 56389.4 - - - 2.4478 - 1.604 0.558 - 95.4 1 2 0 0.0044 17 0 0 0 1.26E+06 8.22E+05 - - - 4.3227 1 221125_WJC_METTL3_EV_vs_WT_F10.12477.12477.4 4.41E-14 23/126 K.HGAPSPSHPISAPQAAAAAALR.R "sp|P35658|NU214_HUMAN,tr|A0A0A0MSW3|A0A0A0MSW3_HUMAN,tr|H0YF36|H0YF36_HUMAN,tr|A0A494C1F2|A0A494C1F2_HUMAN" 4 2077.0817 2.61 143881 12477 4 2077.088681 520.2777 Nuclear pore complex protein Nup214 OS=Homo sapiens OX=9606 GN=NUP214 PE=1 SV=2 9.76 2428.1 - 441314 - - - 3.3513 - 4.091 0.668 - 431.3 1 2 0 0.007 22 0 0 0 9.09E+06 3.48E+06 - - - 5.4993 0.9997 221125_WJC_METTL3_EV_vs_WT_F10.12478.12478.3 2.23E-07 Oct-92 R.RVENSIPAAGETQNVEVAAGPAGK.C "sp|Q15020|SART3_HUMAN,tr|A0A499FI31|A0A499FI31_HUMAN" 2 2364.2034 27.37 143882 12478 3 2364.213693 789.0751 Squamous cell carcinoma antigen recognized by T-cells 3 OS=Homo sapiens OX=9606 GN=SART3 PE=1 SV=1 4.79 2428.3 - 92886.4 - - - 4.3744 - 2.088 0.562 - 92.3 1 2 0 0.0103 24 0 0 0 2.31E+06 8.42E+04 - - - 6.5128 0.9998 221125_WJC_METTL3_EV_vs_WT_F10.12481.12481.3 0.000147 Dec-60 R.SGK[136.11]YDLDFK[136.11]SPDDPSR[166.11].Y "sp|P06733|ENOA_HUMAN,tr|A0A2R8Y6G6|A0A2R8Y6G6_HUMAN" 2 1851.8849 1.57 143883 12481 3 1851.888859 618.3023 Alpha-enolase OS=Homo sapiens OX=9606 GN=ENO1 PE=1 SV=2 4.58 2428.7 - 228266 - - - 2.1232 - 2.371 0.565 - 127.6 1 2 2 0.0039 16 0 0 0 2.92E+07 1.85E+07 - - - 7.0532 1 221125_WJC_METTL3_EV_vs_WT_F10.12489.12489.4 4.21E-09 13/84 R.NHDHQEIAVPVANLK[136.11].L sp|O75607|NPM3_HUMAN 1 1691.8835 1.05 143888 12489 4 1691.886136 423.9781 Nucleoplasmin-3 OS=Homo sapiens OX=9606 GN=NPM3 PE=1 SV=3 5.99 2429.7 - 78441.3 - - - 1.5769 - 2.263 0.592 - 148.6 1 2 0 0.0027 15 0 0 0 3.89E+06 3.71E+06 - - - 4.6702 1 221125_WJC_METTL3_EV_vs_WT_F10.12490.12490.3 3.03E-10 16/56 R.NHDHQEIAVPVANLK.L sp|O75607|NPM3_HUMAN 1 1683.8693 1.11 143889 12490 3 1683.871315 562.297 Nucleoplasmin-3 OS=Homo sapiens OX=9606 GN=NPM3 PE=1 SV=3 5.99 2429.8 - 282124 - - - 1.2157 - 3.369 0.662 - 333.3 1 2 0 0.002 15 0 0 0 9.68E+06 8.69E+06 - - - 9.0895 1 221125_WJC_METTL3_EV_vs_WT_F10.12501.12501.4 7.43E-09 13/84 R.NHDHQEIAVPVANLK.L sp|O75607|NPM3_HUMAN 1 1683.8693 1.02 143896 12501 4 1683.873193 421.9746 Nucleoplasmin-3 OS=Homo sapiens OX=9606 GN=NPM3 PE=1 SV=3 5.99 2431.4 - 150319 - - - 2.3309 - 2.394 0.599 - 153.2 1 2 0 0.0039 15 0 0 0 3.74E+06 3.66E+06 - - - 4.751 0.9995 221125_WJC_METTL3_EV_vs_WT_F10.12502.12502.4 8.12E-10 17/102 K.SK[136.11]EEYQQTWYHEGPNSLK[136.11].V sp|O43172|PRP4_HUMAN 1 2239.0517 3.24 143897 12502 4 2239.058997 560.7702 U4\U6 small nuclear ribonucleoprotein Prp4 OS=Homo sapiens OX=9606 GN=PRPF4 PE=1 SV=2 5.47 2431.5 - 508160 - - - 3.2759 - 3.672 0.486 - 343.2 1 2 1 0.0073 18 0 0 0 3.22E+08 9.95E+07 - - - 3.8997 0.9995 221125_WJC_METTL3_EV_vs_WT_F10.12503.12503.4 4.52E-06 15/114 R.LREHDAAAESLVDQSAALHR.R sp|Q9BRV8|SIKE1_HUMAN 1 2188.0985 6.19 143898 12503 4 2188.106645 548.0319 Suppressor of IKBKE 1 OS=Homo sapiens OX=9606 GN=SIKE1 PE=1 SV=1 5.31 2431.6 - 175317 - - - 3.7261 - 3.199 0.534 - 183.2 1 2 1 0.0082 20 0 0 0 8.43E+06 1.36E+06 - - - 4.2604 0.9991 221125_WJC_METTL3_EV_vs_WT_F10.12507.12507.4 4.22E-05 24/168 R.GAEGILAPQPPPPQQHQERPGAAAIGSAR.G "sp|Q8WWM7|ATX2L_HUMAN,tr|H3BUF6|H3BUF6_HUMAN" 2 2900.5005 1.89 143901 12507 4 2900.509305 726.1324 Ataxin-2-like protein OS=Homo sapiens OX=9606 GN=ATXN2L PE=1 SV=2 6.76 2432.1 - 1.44E+06 - - - 3.0229 - 2.899 0.356 - 235.1 1 2 0 0.0088 29 0 0 0 1.05E+08 5.56E+07 - - - 2.6502 0.9997 221125_WJC_METTL3_EV_vs_WT_F10.12509.12509.4 7.26E-10 18/102 K.SKEEYQQTWYHEGPNSLK.V sp|O43172|PRP4_HUMAN 1 2223.0233 3.25 143903 12509 4 2223.03117 556.7631 U4\U6 small nuclear ribonucleoprotein Prp4 OS=Homo sapiens OX=9606 GN=PRPF4 PE=1 SV=2 5.47 2432.3 - 2.13E+06 - - - 3.5573 - 3.497 0.586 - 402.6 1 2 1 0.0079 18 0 0 0 3.23E+08 9.94E+07 - - - 4.7532 0.9999 221125_WJC_METTL3_EV_vs_WT_F10.12510.12510.4 1.50E-06 14/90 K.VHFFTQDHK[136.11]PSNPLEK[136.11].E "sp|P35813|PPM1A_HUMAN,tr|E9PKB5|E9PKB5_HUMAN" 2 1938.9923 0.54 143904 12510 4 1938.998271 485.7554 Protein phosphatase 1A OS=Homo sapiens OX=9606 GN=PPM1A PE=1 SV=1 6.89 2432.4 - 276560 - - - 3.0815 - 2.808 0.5 - 159.9 1 2 0 0.006 16 0 0 0 1.61E+07 3.00E+07 - - - 3.94 0.9999 221125_WJC_METTL3_EV_vs_WT_F10.12511.12511.4 2.41E-05 15/138 K.TTNPDVHPTEATPSSTFTGIR[166.11]PAR[166.11].V sp|Q8N573|OXR1_HUMAN 1 2572.2785 1.37 143905 12511 4 2572.283925 644.0769 Oxidation resistance protein 1 OS=Homo sapiens OX=9606 GN=OXR1 PE=1 SV=2 6.42 2432.6 - 250296 - - - 2.1211 - 3.019 0.514 - 79.4 1 2 0 0.0055 24 0 0 0 1.13E+07 8.22E+06 - - - 4.053 1 221125_WJC_METTL3_EV_vs_WT_F10.12517.12517.3 5.65E-05 16/56 R.NHDHQEIAVPVANLK[136.11].L sp|O75607|NPM3_HUMAN 1 1691.8835 1.11 143909 12517 3 1691.887142 564.9684 Nucleoplasmin-3 OS=Homo sapiens OX=9606 GN=NPM3 PE=1 SV=3 5.99 2433.4 - 407092 - - - 2.1715 - 3.448 0.572 - 369.4 1 2 0 0.0037 15 0 0 0 9.68E+06 8.69E+06 - - - 8.1461 1 221125_WJC_METTL3_EV_vs_WT_F10.12519.12519.3 4.03E-10 25/68 K.SKEEYQQTWYHEGPNSLK.V sp|O43172|PRP4_HUMAN 1 2223.0233 2.67 143911 12519 3 2223.028889 742.015 U4\U6 small nuclear ribonucleoprotein Prp4 OS=Homo sapiens OX=9606 GN=PRPF4 PE=1 SV=2 5.47 2433.7 - 1.34E+06 - - - 2.5312 - 4.15 0.71 - 1008.5 1 2 1 0.0056 18 0 0 0 1.32E+08 4.95E+07 - - - 9.9979 0.9936 221125_WJC_METTL3_EV_vs_WT_F10.12527.12527.4 0.00991 11/138 K.TTNPDVHPTEATPSSTFTGIRPAR.V sp|Q8N573|OXR1_HUMAN 1 2552.2619 1.37 143915 12527 4 2552.272031 639.0728 Oxidation resistance protein 1 OS=Homo sapiens OX=9606 GN=OXR1 PE=1 SV=2 6.42 2434.8 - 348872 - - - 3.9581 - 2.243 0.294 - 45.2 1 2 0 0.0101 24 0 0 0 1.13E+07 8.22E+06 - - - 2.0415 1 221125_WJC_METTL3_EV_vs_WT_F10.12531.12531.3 3.17E-10 13/72 C.KYVHYEIDAC[160.03]MDSEAPGSK[136.11].D "sp|Q86U44|MTA70_HUMAN,tr|H0YFV6|H0YFV6_HUMAN" 2 2206.9755 - 143917 12531 3 2206.979662 736.6658 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 4.75 2435.4 - 141640 - - - 1.9062 - 2.616 0.719 - 161.7 1 1 0 0.0042 19 0 0 0 - - - - - 8.9175 1 221125_WJC_METTL3_EV_vs_WT_F10.12543.12543.3 2.01E-07 17/72 C.K[136.11]YVHYEIDAC[160.03]MDSEAPGSK[136.11].D "sp|Q86U44|MTA70_HUMAN,tr|H0YFV6|H0YFV6_HUMAN" 2 2214.9897 0.01 143925 12543 3 2214.993132 739.3372 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 4.75 2436.9 - 316555 - - - 1.5698 - 3.384 0.638 - 288.6 1 1 0 0.0035 19 0 0 0 3.36E+05 2.35E+07 - - - 8.6471 1 221125_WJC_METTL3_EV_vs_WT_F10.12547.12547.4 1.12E-12 28/216 K.LASVPAGGAVAVSAAPGSAAPAAGSAPAAAEEKKDEK.K "sp|P05387|RLA2_HUMAN,tr|H0YDD8|H0YDD8_HUMAN" 2 3273.6841 1.39 143928 12547 4 3273.690599 819.4283 60S acidic ribosomal protein P2 OS=Homo sapiens OX=9606 GN=RPLP2 PE=1 SV=1 4.87 2437.4 - 393520 - - - 1.9852 - 4.527 0.623 - 310.4 1 2 1 0.0065 37 0 0 0 5.01E+08 3.60E+08 - - - 5.0895 1 221125_WJC_METTL3_EV_vs_WT_F10.12548.12548.3 3.42E-12 18/124 R.ALQRPSAAAPQAENGPAAAPAVAAPAATEAPK.M "sp|Q15020|SART3_HUMAN,tr|A0A499FI31|A0A499FI31_HUMAN" 2 2964.5417 20.28 143929 12548 3 2964.544653 989.1879 Squamous cell carcinoma antigen recognized by T-cells 3 OS=Homo sapiens OX=9606 GN=SART3 PE=1 SV=1 6.19 2437.5 - 136487 - - - 0.985 - 3.542 0.714 - 174.9 1 2 0 0.0029 32 0 0 0 8.55E+06 4.22E+05 - - - 9.4092 0.9996 221125_WJC_METTL3_EV_vs_WT_F10.12553.12553.4 1.14E-06 18/168 R.GAEGILAPQPPPPQQHQER[166.11]PGAAAIGSAR[166.11].G "sp|Q8WWM7|ATX2L_HUMAN,tr|H3BUF6|H3BUF6_HUMAN" 2 2920.5171 1.89 143931 12553 4 2920.52255 731.1365 Ataxin-2-like protein OS=Homo sapiens OX=9606 GN=ATXN2L PE=1 SV=2 6.76 2438.3 - 306936 - - - 1.874 - 3.472 0.352 - 155 1 2 0 0.0055 29 0 0 0 1.05E+08 5.56E+07 - - - 2.6719 0.9995 221125_WJC_METTL3_EV_vs_WT_F10.12566.12566.3 5.38E-06 12/144 K.LASVPAGGAVAVSAAPGSAAPAAGSAPAAAEEKKDEK.K "sp|P05387|RLA2_HUMAN,tr|H0YDD8|H0YDD8_HUMAN" 2 3273.6841 1.93 143940 12566 3 3273.695794 1092.2353 60S acidic ribosomal protein P2 OS=Homo sapiens OX=9606 GN=RPLP2 PE=1 SV=1 4.87 2440 - 110792 - - - 3.5721 - 2.538 0.595 - 54.3 1 2 1 0.0117 37 0 0 0 1.07E+07 5.57E+06 - - - 7.3132 0.9997 221125_WJC_METTL3_EV_vs_WT_F10.12567.12567.4 0.000217 10/144 R.RAPSTSPSFEGTQETYTVAHEENVR.F sp|Q9BUT9|MCRI2_HUMAN 1 2792.3002 1.72 143941 12567 4 2792.309632 699.0823 MAPK regulated corepressor interacting protein 2 OS=Homo sapiens OX=9606 GN=MCRIP2 PE=1 SV=2 4.91 2440.1 - 76391.3 - - - 3.3904 - 1.959 0.463 - 39.6 1 2 0 0.0095 25 0 0 0 5.39E+07 3.12E+07 - - - 3.4672 0.9952 221125_WJC_METTL3_EV_vs_WT_F10.12575.12575.3 0.00794 10/144 K.LASVPAGGAVAVSAAPGSAAPAAGSAPAAAEEK[136.11]K[136.11]DEK[136.11].K "sp|P05387|RLA2_HUMAN,tr|H0YDD8|H0YDD8_HUMAN" 2 3297.7267 1.93 143946 12575 3 3297.719525 1100.2495 60S acidic ribosomal protein P2 OS=Homo sapiens OX=9606 GN=RPLP2 PE=1 SV=1 4.87 2441.2 - 175470 - - - -2.1757 - 1.841 0.346 - 32.3 1 2 1 -0.0072 37 0 0 0 1.07E+07 5.57E+06 - - - 3.7997 0.9952 221125_WJC_METTL3_EV_vs_WT_F10.12576.12576.2 0.0105 16-Jul R.QLDSIVGER.G "sp|P48668|K2C6C_HUMAN,sp|P13647|K2C5_HUMAN,sp|P02538|K2C6A_HUMAN,tr|F8W0C6|F8W0C6_HUMAN" 4 1015.5298 9.29 143947 12576 2 1015.533391 508.7722 "Keratin, type II cytoskeletal 6C OS=Homo sapiens OX=9606 GN=KRT6C PE=1 SV=3" 4.37 2441.4 - 160586 - - - 3.5125 - 1.323 0.381 - 145.5 1 2 0 0.0036 9 0 0 0 3.24E+06 3.49E+05 - - - 2.6637 1 221125_WJC_METTL3_EV_vs_WT_F10.12581.12581.4 1.89E-11 20/144 R.R[166.11]APSTSPSFEGTQETYTVAHEENVR[166.11].F sp|Q9BUT9|MCRI2_HUMAN 1 2812.3167 1.73 143949 12581 4 2812.319077 704.0865 MAPK regulated corepressor interacting protein 2 OS=Homo sapiens OX=9606 GN=MCRIP2 PE=1 SV=2 4.91 2442.1 - 354866 - - - 0.8434 - 4.091 0.647 - 222 1 2 0 0.0024 25 0 0 0 5.39E+07 3.12E+07 - - - 5.305 1 221125_WJC_METTL3_EV_vs_WT_F10.12584.12584.4 7.14E-07 19/138 R.ASPAPGSGHPEGPGAHLDMNSLDR[166.11].A sp|O94826|TOM70_HUMAN 1 2379.0901 2.69 143952 12584 4 2379.092805 595.7798 Mitochondrial import receptor subunit TOM70 OS=Homo sapiens OX=9606 GN=TOMM70 PE=1 SV=1 5.21 2442.4 - 577934 - - - 1.1261 - 2.948 0.484 - 228.5 1 2 0 0.0027 24 0 0 0 3.67E+07 1.36E+07 - - - 3.785 0.9995 221125_WJC_METTL3_EV_vs_WT_F10.12604.12604.3 3.82E-05 Dec-36 K.R[166.11]LHVSNIPFR[166.11].F "sp|O43251|RFOX2_HUMAN,sp|Q9NWB1|RFOX1_HUMAN,sp|A6NFN3|RFOX3_HUMAN,tr|A0A6Q8PGE0|A0A6Q8PGE0_HUMAN,tr|A0A6Q8PH77|A0A6Q8PH77_HUMAN,tr|A0A286YEU2|A0A286YEU2_HUMAN,tr|A0A087X2B1|A0A087X2B1_HUMAN,tr|F8VR27|F8VR27_HUMAN,tr|B7Z1U7|B7Z1U7_HUMAN,tr|B0QYY6|B0QYY6_HUMAN,tr|B0QYV1|B0QYV1_HUMAN,tr|A0A6Q8PHA3|A0A6Q8PHA3_HUMAN,tr|A0A3B3ITL7|A0A3B3ITL7_HUMAN,tr|F8VZY7|F8VZY7_HUMAN,tr|B0QYY4|B0QYY4_HUMAN,tr|J3KNW3|J3KNW3_HUMAN,tr|F8VZG9|F8VZG9_HUMAN,tr|J3QRF4|J3QRF4_HUMAN,tr|F8VRS4|F8VRS4_HUMAN,tr|A0A6Q8PFM4|A0A6Q8PFM4_HUMAN,tr|S4R469|S4R469_HUMAN,tr|A0A804HKG7|A0A804HKG7_HUMAN,tr|A0A0G2JRA5|A0A0G2JRA5_HUMAN,tr|A0A804HJM2|A0A804HJM2_HUMAN,tr|J3QQZ2|J3QQZ2_HUMAN,tr|I3L1D4|I3L1D4_HUMAN,tr|B0QYY7|B0QYY7_HUMAN,tr|A0A0G2JSB3|A0A0G2JSB3_HUMAN" 28 1257.7209 1.09 143961 12604 3 1257.718659 420.2476 RNA binding protein fox-1 homolog 2 OS=Homo sapiens OX=9606 GN=RBFOX2 PE=1 SV=3 12 2445.1 - 169843 - - - -1.7929 - 2.386 0.271 - 263.8 1 2 0 -0.0023 10 0 0 0 8.83E+06 8.07E+06 - - - 4.1004 0.9971 221125_WJC_METTL3_EV_vs_WT_F10.12613.12613.2 0.0564 26-Jun K.K[136.11]HPDASVNFSEFSK[136.11].K "sp|P09429|HMGB1_HUMAN,tr|Q5T7C4|Q5T7C4_HUMAN" 2 1607.7915 0.001 143966 12613 2 1607.790488 804.903 High mobility group protein B1 OS=Homo sapiens OX=9606 GN=HMGB1 PE=1 SV=3 6.75 2446.2 - 157367 - - - -0.6114 - 1.077 0.313 - 65.2 1 2 0 -0.001 14 0 0 0 0.00E+00 1.76E+06 - - - 1.5387 0.9999 221125_WJC_METTL3_EV_vs_WT_F10.12623.12623.4 9.98E-10 31/216 K.LASVPAGGAVAVSAAPGSAAPAAGSAPAAAEEK[136.11]K[136.11]DEK[136.11].K "sp|P05387|RLA2_HUMAN,tr|H0YDD8|H0YDD8_HUMAN" 2 3297.7267 1.39 143972 12623 4 3297.720488 825.439 60S acidic ribosomal protein P2 OS=Homo sapiens OX=9606 GN=RPLP2 PE=1 SV=1 4.87 2447.5 - 4.91E+06 - - - -1.8837 - 4.62 0.582 - 375.7 1 2 1 -0.0062 37 0 0 0 5.01E+08 3.60E+08 - - - 4.7387 0.9999 221125_WJC_METTL3_EV_vs_WT_F10.12626.12626.3 0.0775 Dec-36 K.RLHVSNIPFR.F "sp|O43251|RFOX2_HUMAN,sp|Q9NWB1|RFOX1_HUMAN,sp|A6NFN3|RFOX3_HUMAN,tr|A0A6Q8PGE0|A0A6Q8PGE0_HUMAN,tr|A0A6Q8PH77|A0A6Q8PH77_HUMAN,tr|A0A286YEU2|A0A286YEU2_HUMAN,tr|A0A087X2B1|A0A087X2B1_HUMAN,tr|F8VR27|F8VR27_HUMAN,tr|B7Z1U7|B7Z1U7_HUMAN,tr|B0QYY6|B0QYY6_HUMAN,tr|B0QYV1|B0QYV1_HUMAN,tr|A0A6Q8PHA3|A0A6Q8PHA3_HUMAN,tr|A0A3B3ITL7|A0A3B3ITL7_HUMAN,tr|F8VZY7|F8VZY7_HUMAN,tr|B0QYY4|B0QYY4_HUMAN,tr|J3KNW3|J3KNW3_HUMAN,tr|F8VZG9|F8VZG9_HUMAN,tr|J3QRF4|J3QRF4_HUMAN,tr|F8VRS4|F8VRS4_HUMAN,tr|A0A6Q8PFM4|A0A6Q8PFM4_HUMAN,tr|S4R469|S4R469_HUMAN,tr|A0A804HKG7|A0A804HKG7_HUMAN,tr|A0A0G2JRA5|A0A0G2JRA5_HUMAN,tr|A0A804HJM2|A0A804HJM2_HUMAN,tr|J3QQZ2|J3QQZ2_HUMAN,tr|I3L1D4|I3L1D4_HUMAN,tr|B0QYY7|B0QYY7_HUMAN,tr|A0A0G2JSB3|A0A0G2JSB3_HUMAN" 28 1237.7044 1.17 143975 12626 3 1237.703647 413.5754 RNA binding protein fox-1 homolog 2 OS=Homo sapiens OX=9606 GN=RBFOX2 PE=1 SV=3 12 2447.8 - 311411 - - - -0.5874 - 2.344 0.342 - 130.9 1 2 0 -0.0007 10 0 0 0 1.76E+07 1.51E+07 - - - 4.8406 1 221125_WJC_METTL3_EV_vs_WT_F10.12629.12629.3 0.000551 16/52 K.K[136.11]HPDASVNFSEFSK[136.11].K "sp|P09429|HMGB1_HUMAN,tr|Q5T7C4|Q5T7C4_HUMAN" 2 1607.7915 0.18 143977 12629 3 1607.790772 536.9378 High mobility group protein B1 OS=Homo sapiens OX=9606 GN=HMGB1 PE=1 SV=3 6.75 2448.2 - 4.06E+06 - - - -0.4348 - 3.05 0.588 - 462.2 1 2 0 -0.0007 14 0 0 0 2.65E+07 1.49E+08 - - - 8.0589 0.895 221125_WJC_METTL3_EV_vs_WT_F10.12633.12633.3 0.0028 Dec-64 R.AQVQEFC[160.03]DYGTK[136.11]EEC[160.03]MK[136.11].A "sp|Q86U44|MTA70_HUMAN,tr|H0YFV6|H0YFV6_HUMAN" 2 2137.909 0.03 143978 12633 3 2138.900913 713.6436 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 4.41 2448.8 - 546444 - - - 463.9814 - 2.353 0.506 - 122.3 1 2 1 0.9919 17 0 0 0 1.29E+05 4.75E+06 - - - 6.0684 0.9946 221125_WJC_METTL3_EV_vs_WT_F10.12635.12635.3 0.059 Jul-56 K.AVDQHNAEAQDIFGK.N "sp|P52732|KIF11_HUMAN,tr|A0A7I2YQY4|A0A7I2YQY4_HUMAN,tr|A0A7I2V3A9|A0A7I2V3A9_HUMAN" 3 1641.7747 9.74 143980 12635 3 1641.776555 548.2655 Kinesin-like protein KIF11 OS=Homo sapiens OX=9606 GN=KIF11 PE=1 SV=2 4.54 2449 - 228531 - - - 1.1311 - 1.336 0.269 - 50.7 1 2 0 0.0019 15 0 0 0 6.12E+06 6.28E+05 - - - 2.2945 0.9576 221125_WJC_METTL3_EV_vs_WT_F10.12638.12638.3 1.63 Oct-84 R.ISAEVEVVEMVENDISAFTYER[166.11].T "sp|Q9Y666|S12A7_HUMAN,tr|A0A0G2JQE3|A0A0G2JQE3_HUMAN,tr|A0A0U1RR18|A0A0U1RR18_HUMAN,tr|A0A0G2JNW7|A0A0G2JNW7_HUMAN,tr|H0YB78|H0YB78_HUMAN" 5 2539.2028 1.94 143982 12638 3 2539.203016 847.4082 Solute carrier family 12 member 7 OS=Homo sapiens OX=9606 GN=SLC12A7 PE=1 SV=3 3.83 2449.4 - 966714 - - - 0.1024 - 1.452 0.137 - 54.7 1 2 0 0.0003 22 0 0 0 3.22E+07 1.66E+07 - - - 0.9515 0.9994 221125_WJC_METTL3_EV_vs_WT_F10.12640.12640.4 0.000211 13/114 K.VQSYLENPTSYHLQQSQHQK.V "sp|P19484|TFEB_HUMAN,tr|B0QYS7|B0QYS7_HUMAN,tr|A0A1B0GXL9|A0A1B0GXL9_HUMAN,tr|B1AKB4|B1AKB4_HUMAN,tr|B1AKB1|B1AKB1_HUMAN,tr|B1AKB2|B1AKB2_HUMAN,tr|A0A7I2YQR9|A0A7I2YQR9_HUMAN,tr|B0QYS6|B0QYS6_HUMAN" 8 2414.1615 5.76 143983 12640 4 2414.155164 604.5476 Transcription factor EB OS=Homo sapiens OX=9606 GN=TFEB PE=1 SV=3 6.89 2449.6 - 380337 - - - -2.6191 - 2.821 0.356 - 66.2 1 2 0 -0.0063 20 0 0 0 8.08E+06 1.40E+06 - - - 2.6696 0.834 221125_WJC_METTL3_EV_vs_WT_F10.12641.12641.3 0.0338 5/112 R.VPSSSSISSSSGSPYHPC[160.03]GSASQSPC[160.03]SPP.G sp|Q15517|CDSN_HUMAN 1 2877.2182 - 143984 12641 3 2877.21159 960.08 Corneodesmosin OS=Homo sapiens OX=9606 GN=CDSN PE=1 SV=3 6.69 2449.7 - 223428 - - - -2.2807 - 0.908 0.458 - 8.4 1 1 0 -0.0066 29 0 0 0 - - - - - 3.4224 0.9887 221125_WJC_METTL3_EV_vs_WT_F10.12642.12642.4 0.0241 11/102 R.ETHSVDRLPSALTATAC[160.03]K.S "sp|Q92615|LAR4B_HUMAN,tr|A0A087X183|A0A087X183_HUMAN,tr|H0Y641|H0Y641_HUMAN,tr|H0Y4V9|H0Y4V9_HUMAN" 4 1955.9735 1.29 143985 12642 4 1955.969265 490.0006 La-related protein 4B OS=Homo sapiens OX=9606 GN=LARP4B PE=1 SV=3 6.84 2449.9 - 312316 - - - -2.1524 - 2.268 0.266 - 86.9 1 2 1 -0.0042 18 0 0 0 3.83E+07 2.96E+07 - - - 1.8206 0.9999 221125_WJC_METTL3_EV_vs_WT_F10.12649.12649.3 0.000759 Oct-48 R.SIFQHIQSAQSQR[166.11].S "sp|Q9Y2W1|TR150_HUMAN,tr|A0A3B3ITZ9|A0A3B3ITZ9_HUMAN" 2 1538.7829 2.54 143990 12649 3 1538.780763 513.9349 Thyroid hormone receptor-associated protein 3 OS=Homo sapiens OX=9606 GN=THRAP3 PE=1 SV=2 9.49 2450.8 - 317611 - - - -1.3946 - 1.881 0.458 - 99.8 1 2 0 -0.0021 13 0 0 0 7.35E+07 2.89E+07 - - - 5.3587 1 221125_WJC_METTL3_EV_vs_WT_F10.12650.12650.4 1.36E-06 16/114 K.GGAAVDPDSGLEHSAHVLEK[136.11].G "sp|P09874|PARP1_HUMAN,tr|A0A7I2V3E1|A0A7I2V3E1_HUMAN" 2 1995.9741 1.12 143991 12650 4 1995.970845 500.0008 Poly [ADP-ribose] polymerase 1 OS=Homo sapiens OX=9606 GN=PARP1 PE=1 SV=4 4.72 2450.9 - 128515 - - - -1.6473 - 3.185 0.55 - 221.2 1 2 0 -0.0033 20 0 0 0 9.38E+06 8.34E+06 - - - 4.3996 1 221125_WJC_METTL3_EV_vs_WT_F10.12654.12654.3 4.39E-06 13/48 R.SIFQHIQSAQSQR.S "sp|Q9Y2W1|TR150_HUMAN,tr|A0A3B3ITZ9|A0A3B3ITZ9_HUMAN" 2 1528.7746 2.55 143993 12654 3 1528.773522 510.5988 Thyroid hormone receptor-associated protein 3 OS=Homo sapiens OX=9606 GN=THRAP3 PE=1 SV=2 9.49 2451.5 - 1.04E+06 - - - -0.7307 - 2.323 0.533 - 167.1 1 2 0 -0.0011 13 0 0 0 7.35E+07 2.89E+07 - - - 6.7673 0.9999 221125_WJC_METTL3_EV_vs_WT_F10.12655.12655.3 1.67E-07 19/68 R.ETHSVDR[166.11]LPSALTATAC[160.03]K[136.11].S "sp|Q92615|LAR4B_HUMAN,tr|A0A087X183|A0A087X183_HUMAN,tr|H0Y641|H0Y641_HUMAN,tr|H0Y4V9|H0Y4V9_HUMAN" 4 1973.9959 1.37 143994 12655 3 1973.995661 659.0059 La-related protein 4B OS=Homo sapiens OX=9606 GN=LARP4B PE=1 SV=3 6.84 2451.6 - 516509 - - - -0.1439 - 3.578 0.508 - 447.6 1 2 1 -0.0003 18 0 0 0 2.83E+07 2.06E+07 - - - 7.378 0.9996 221125_WJC_METTL3_EV_vs_WT_F10.12656.12656.4 6.35E-05 17/102 R.ETHSVDR[166.11]LPSALTATAC[160.03]K[136.11].S "sp|Q92615|LAR4B_HUMAN,tr|A0A087X183|A0A087X183_HUMAN,tr|H0Y641|H0Y641_HUMAN,tr|H0Y4V9|H0Y4V9_HUMAN" 4 1973.9959 1.29 143995 12656 4 1973.996184 494.5063 La-related protein 4B OS=Homo sapiens OX=9606 GN=LARP4B PE=1 SV=3 6.84 2451.7 - 781021 - - - 0.1211 - 3.015 0.42 - 236.8 1 2 1 0.0002 18 0 0 0 3.83E+07 2.96E+07 - - - 3.2597 1 221125_WJC_METTL3_EV_vs_WT_F10.12658.12658.4 7.21E-05 17/114 K.GGAAVDPDSGLEHSAHVLEK.G "sp|P09874|PARP1_HUMAN,tr|A0A7I2V3E1|A0A7I2V3E1_HUMAN" 2 1987.9599 1.12 143997 12658 4 1987.95698 497.9973 Poly [ADP-ribose] polymerase 1 OS=Homo sapiens OX=9606 GN=PARP1 PE=1 SV=4 4.72 2452 - 180697 - - - -1.4854 - 3.025 0.477 - 223.7 1 2 0 -0.003 20 0 0 0 9.11E+06 8.13E+06 - - - 3.7471 1 221125_WJC_METTL3_EV_vs_WT_F10.12664.12664.3 0.0289 23/72 K.TEELNKEVASNSELVQSSR.S "sp|P08779|K1C16_HUMAN,tr|K7ENW6|K7ENW6_HUMAN" 2 2119.0393 719.42 144001 12664 3 2119.038975 707.3537 "Keratin, type I cytoskeletal 16 OS=Homo sapiens OX=9606 GN=KRT16 PE=1 SV=4" 4.49 2452.8 - 1.03E+06 - - - -0.1562 - 4.334 0.618 - 712.4 1 2 1 -0.0003 19 0 0 0 7.03E+07 9.77E+04 - - - 9.0329 0.9999 221125_WJC_METTL3_EV_vs_WT_F10.12667.12667.3 7.62E-05 15/92 K.EVTQATQPEAIPQGTNITEEKPGR.K "sp|Q6W2J9|BCOR_HUMAN,tr|H7BZ37|H7BZ37_HUMAN,tr|H7C2V9|H7C2V9_HUMAN,tr|H7BYY2|H7BYY2_HUMAN,tr|H7C231|H7C231_HUMAN" 5 2593.2984 2.17 144004 12667 3 2593.299185 865.4401 BCL-6 corepressor OS=Homo sapiens OX=9606 GN=BCOR PE=1 SV=1 4.49 2453.2 - 215557 - - - 0.3127 - 2.156 0.489 - 125.5 1 2 0 0.0008 24 0 0 0 4.93E+07 2.27E+07 - - - 5.776 1 221125_WJC_METTL3_EV_vs_WT_F10.12668.12668.3 9.77E-08 Dec-56 K.KAEAGAGSATEFQFR.G "sp|Q9NQ39|RS10L_HUMAN,sp|P46783|RS10_HUMAN" 2 1568.7583 1.32 144005 12668 3 1568.760727 523.9267 Putative 40S ribosomal protein S10-like OS=Homo sapiens OX=9606 GN=RPS10P5 PE=5 SV=1 6.14 2453.3 - 184614 - - - 1.5343 - 2.511 0.574 - 228.5 1 2 0 0.0024 15 0 0 0 2.36E+07 1.79E+07 - - - 7.3413 1 221125_WJC_METTL3_EV_vs_WT_F10.12672.12672.2 1.66E-08 16/24 R.SIFQHIQSAQSQR.S "sp|Q9Y2W1|TR150_HUMAN,tr|A0A3B3ITZ9|A0A3B3ITZ9_HUMAN" 2 1528.7746 3.15 144007 12672 2 1528.774239 765.3946 Thyroid hormone receptor-associated protein 3 OS=Homo sapiens OX=9606 GN=THRAP3 PE=1 SV=2 9.49 2453.8 - 254144 - - - -0.2616 - 3.066 0.608 - 1116 1 2 0 -0.0004 13 0 0 0 7.81E+06 2.48E+06 - - - 6.407 1 221125_WJC_METTL3_EV_vs_WT_F10.12674.12674.3 3.14E-06 13/56 K.K[136.11]AEAGAGSATEFQFR[166.11].G "sp|Q9NQ39|RS10L_HUMAN,sp|P46783|RS10_HUMAN" 2 1586.7808 1.32 144009 12674 3 1586.78101 529.9342 Putative 40S ribosomal protein S10-like OS=Homo sapiens OX=9606 GN=RPS10P5 PE=5 SV=1 6.14 2454.1 - 268432 - - - 0.1386 - 2.527 0.515 - 267.6 1 2 0 0.0002 15 0 0 0 2.36E+07 1.79E+07 - - - 6.7006 0.9991 221125_WJC_METTL3_EV_vs_WT_F10.12675.12675.3 0.00248 Aug-76 K.GGAAVDPDSGLEHSAHVLEK.G "sp|P09874|PARP1_HUMAN,tr|A0A7I2V3E1|A0A7I2V3E1_HUMAN" 2 1987.9599 0.6 144010 12675 3 1987.960153 663.6606 Poly [ADP-ribose] polymerase 1 OS=Homo sapiens OX=9606 GN=PARP1 PE=1 SV=4 4.72 2454.2 - 175671 - - - 0.1107 - 1.716 0.316 - 63.2 1 2 0 0.0002 20 0 0 0 4.02E+06 6.75E+06 - - - 3.3731 1 221125_WJC_METTL3_EV_vs_WT_F10.12676.12676.3 8.98E-09 12/116 R.AGEPNSPDAEEANSPDVTAGC[160.03]DPAGVHPPR.- sp|Q08J23|NSUN2_HUMAN 1 3013.3108 1.65 144011 12676 3 3013.308359 1005.4442 RNA cytosine C(5)-methyltransferase NSUN2 OS=Homo sapiens OX=9606 GN=NSUN2 PE=1 SV=2 4.01 2454.4 - 172138 - - - -0.8121 - 2.611 0.759 - 67.4 1 2 0 -0.0024 30 0 0 0 1.07E+07 6.52E+06 - - - 9.2094 0.9999 221125_WJC_METTL3_EV_vs_WT_F10.12681.12681.4 0.000123 10/144 K.VEELPPKPLEQGDETPKPPKPDPLK.L sp|P48634|PRC2A_HUMAN 1 2777.4851 1.56 144014 12681 4 2777.487792 695.3786 Protein PRRC2A OS=Homo sapiens OX=9606 GN=PRRC2A PE=1 SV=3 4.66 2455 - 204334 - - - 0.9649 - 1.994 0.481 - 39.6 1 2 0 0.0027 25 0 0 0 1.39E+07 8.89E+06 - - - 3.6314 0.9999 221125_WJC_METTL3_EV_vs_WT_F10.12682.12682.3 1.20E-06 16/48 R.NREEEWDPEYTPK.S "sp|Q9Y2W1|TR150_HUMAN,tr|A0A3B3ITZ9|A0A3B3ITZ9_HUMAN" 2 1691.7427 3.29 144015 12682 3 1691.743178 564.9215 Thyroid hormone receptor-associated protein 3 OS=Homo sapiens OX=9606 GN=THRAP3 PE=1 SV=2 4.25 2455.2 - 633600 - - - 0.2648 - 2.68 0.596 - 517.5 1 2 1 0.0004 13 0 0 0 6.21E+07 1.89E+07 - - - 7.8575 1 221125_WJC_METTL3_EV_vs_WT_F10.12683.12683.3 1.35E-06 21/92 K.EVTQATQPEAIPQGTNITEEK[136.11]PGR[166.11].K "sp|Q6W2J9|BCOR_HUMAN,tr|H7BZ37|H7BZ37_HUMAN,tr|H7C2V9|H7C2V9_HUMAN,tr|H7BYY2|H7BYY2_HUMAN,tr|H7C231|H7C231_HUMAN" 5 2611.3208 2.17 144016 12683 3 2611.316494 871.4476 BCL-6 corepressor OS=Homo sapiens OX=9606 GN=BCOR PE=1 SV=1 4.49 2455.3 - 447609 - - - -1.6658 - 3.274 0.489 - 301.1 1 2 0 -0.0043 24 0 0 0 4.93E+07 2.27E+07 - - - 6.7453 1 221125_WJC_METTL3_EV_vs_WT_F10.12690.12690.3 6.39E-10 18/76 R.WQPDTEEEYEDSSGNVVNKK.T sp|Q12874|SF3A3_HUMAN 1 2353.0346 7.8 144021 12690 3 2353.025958 785.3521 Splicing factor 3A subunit 3 OS=Homo sapiens OX=9606 GN=SF3A3 PE=1 SV=1 4.08 2456.3 - 629146 - - - -3.6787 - 3.327 0.738 - 362.4 1 2 0 -0.0087 20 0 0 0 1.28E+07 1.64E+06 - - - 9.6818 0.9992 221125_WJC_METTL3_EV_vs_WT_F10.12695.12695.3 3.58E-06 9/116 R.AGEPNSPDAEEANSPDVTAGC[160.03]DPAGVHPPR[166.11].- sp|Q08J23|NSUN2_HUMAN 1 3023.3191 1.64 144026 12695 3 3024.319596 1008.7803 RNA cytosine C(5)-methyltransferase NSUN2 OS=Homo sapiens OX=9606 GN=NSUN2 PE=1 SV=2 4.01 2456.9 - 162931 - - - 330.9343 - 1.798 0.618 - 38.8 1 2 0 1.0005 30 0 0 0 1.07E+07 6.52E+06 - - - 6.5027 0.9999 221125_WJC_METTL3_EV_vs_WT_F10.12700.12700.2 2.01E-05 22-Dec R.AQVQEFC[160.03]DYGTK[136.11].E "sp|Q86U44|MTA70_HUMAN,tr|H0YFV6|H0YFV6_HUMAN" 2 1452.6435 0.01 144029 12700 2 1452.643882 727.329 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 4.37 2457.5 - 1.53E+06 - - - 0.2767 - 2.629 0.55 - 463.2 1 2 0 0.0004 12 0 0 0 1.17E+06 1.10E+08 - - - 5.6465 1 221125_WJC_METTL3_EV_vs_WT_F10.12709.12709.3 1.01E-05 Sep-44 R.AQVQEFC[160.03]DYGTK[136.11].E "sp|Q86U44|MTA70_HUMAN,tr|H0YFV6|H0YFV6_HUMAN" 2 1452.6435 0.001 144034 12709 3 1452.642912 485.2218 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 4.37 2458.8 - 134040 - - - -0.391 - 2.089 0.572 - 104.1 1 2 0 -0.0006 12 0 0 0 0.00E+00 4.70E+06 - - - 6.9591 0.9997 221125_WJC_METTL3_EV_vs_WT_F10.12719.12719.3 7.08E-06 Aug-76 R.WQPDTEEEYEDSSGNVVNK[136.11]K[136.11].T sp|Q12874|SF3A3_HUMAN 1 2369.063 7.73 144040 12719 3 2369.061559 790.6949 Splicing factor 3A subunit 3 OS=Homo sapiens OX=9606 GN=SF3A3 PE=1 SV=1 4.08 2460 - 87138.7 - - - -0.6142 - 1.63 0.416 - 58.8 1 2 0 -0.0015 20 0 0 0 1.27E+07 1.64E+06 - - - 4.3629 1 221125_WJC_METTL3_EV_vs_WT_F10.12720.12720.3 6.73E-07 10/104 R.GTEAGQVGEPGIPTGEAGPSC[160.03]SSASDK[136.11].L sp|O15355|PPM1G_HUMAN 1 2553.138 0.86 144041 12720 3 2553.141145 852.0533 Protein phosphatase 1G OS=Homo sapiens OX=9606 GN=PPM1G PE=1 SV=1 4 2460.1 - 125857 - - - 1.2162 - 2.272 0.625 - 80.6 1 2 0 0.0031 27 0 0 0 4.99E+06 5.81E+06 - - - 7.3953 1 221125_WJC_METTL3_EV_vs_WT_F10.12725.12725.4 1.33E-05 15/120 R.K[136.11]EDLFGR[166.11]PSQGLYSSSASSGK[136.11].C "sp|O95071|UBR5_HUMAN,tr|E7EMW7|E7EMW7_HUMAN" 2 2226.1127 0.47 144044 12725 4 2226.114784 557.5355 E3 ubiquitin-protein ligase UBR5 OS=Homo sapiens OX=9606 GN=UBR5 PE=1 SV=2 8.5 2460.8 - 704216 - - - 0.938 - 2.955 0.475 - 156.5 1 2 0 0.0021 21 0 0 0 9.16E+06 1.96E+07 - - - 3.7181 0.9985 221125_WJC_METTL3_EV_vs_WT_F10.12734.12734.3 2.58E-05 8/100 R.MSGEC[160.03]APNVSVSVSTSHTTISGGGSR.G sp|P04264|K2C1_HUMAN 1 2564.1595 999 144049 12734 3 2565.157175 855.7271 "Keratin, type II cytoskeletal 1 OS=Homo sapiens OX=9606 GN=KRT1 PE=1 SV=6" 6.5 2462 - 168865 - - - 389.0791 - 2.271 0.591 - 44.2 1 2 0 0.9977 26 0 0 0 2.41E+06 0.00E+00 - - - 6.7397 0.9998 221125_WJC_METTL3_EV_vs_WT_F10.12737.12737.4 6.67E-05 14/96 R.ADTQTYQPYNKDWIKEK.L sp|P84090|ERH_HUMAN 1 2127.0273 2.4 144051 12737 4 2127.029096 532.7641 Enhancer of rudimentary homolog OS=Homo sapiens OX=9606 GN=ERH PE=1 SV=1 6.16 2462.3 - 434195 - - - 0.8519 - 2.3 0.463 - 114.8 1 2 2 0.0018 17 0 0 0 1.34E+08 5.58E+07 - - - 3.5446 0.912 221125_WJC_METTL3_EV_vs_WT_F10.12741.12741.4 5.38E-06 13/114 P.K[136.11]PSTASAVPELATDPELEK[136.11]K[136.11].L "sp|Q86U44|MTA70_HUMAN,tr|B4E349|B4E349_HUMAN,tr|F5H6D8|F5H6D8_HUMAN,tr|H0YFV6|H0YFV6_HUMAN,tr|B4DTN4|B4DTN4_HUMAN" 5 2134.1584 0 144053 12741 4 2134.14766 534.5469 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 4.87 2462.9 - 392246 - - - -5.016 - 2.861 0.452 - 96.2 1 1 0 -0.0107 20 0 0 0 1.99E+05 5.92E+07 - - - 3.5087 0.9998 221125_WJC_METTL3_EV_vs_WT_F10.12743.12743.4 1.69E-05 14/96 R.ADTQTYQPYNK[136.11]DWIK[136.11]EK[136.11].L sp|P84090|ERH_HUMAN 1 2151.0699 2.39 144054 12743 4 2151.070607 538.7747 Enhancer of rudimentary homolog OS=Homo sapiens OX=9606 GN=ERH PE=1 SV=1 6.16 2463.1 - 452649 - - - 0.3356 - 3.018 0.487 - 180.8 1 2 2 0.0007 17 0 0 0 1.33E+08 5.57E+07 - - - 3.8482 0.9996 221125_WJC_METTL3_EV_vs_WT_F10.12744.12744.3 0.00221 Sep-44 K.QQHVIETLIGK[136.11]K[136.11].Q "sp|P48643|TCPE_HUMAN,tr|E9PCA1|E9PCA1_HUMAN,tr|B7ZAR1|B7ZAR1_HUMAN,tr|E7ENZ3|E7ENZ3_HUMAN" 4 1408.8373 0.51 144055 12744 3 1408.836222 470.6197 T-complex protein 1 subunit epsilon OS=Homo sapiens OX=9606 GN=CCT5 PE=1 SV=1 8.6 2463.2 - 165122 - - - -0.7645 - 1.509 0.389 - 124.1 1 2 0 -0.0011 12 0 0 0 5.45E+06 1.06E+07 - - - 4.0171 0.9948 221125_WJC_METTL3_EV_vs_WT_F10.12745.12745.3 0.000787 7/104 R.IR[166.11]LEDGQTADGQTEEAAEPGEQLQTQK[136.11].R "sp|Q96G46|DUS3L_HUMAN,tr|K7EJX8|K7EJX8_HUMAN,tr|K7EPA4|K7EPA4_HUMAN" 3 2959.4126 1.35 144056 12745 3 2959.42399 987.4781 tRNA-dihydrouridine(47) synthase [NAD(P)(+)]-like OS=Homo sapiens OX=9606 GN=DUS3L PE=1 SV=2 4 2463.4 - 123489 - - - 3.8582 - 1.596 0.462 - 25 1 2 1 0.0114 27 0 0 0 1.03E+06 7.63E+05 - - - 4.7632 1 221125_WJC_METTL3_EV_vs_WT_F10.12754.12754.3 1.17E-08 12/112 R.VPSAAC[160.03]PPFPPHGAPVSASSSSSSPGGSR.G sp|Q9H7S9|ZN703_HUMAN 1 2734.2769 2.16 144061 12754 3 2734.278713 912.4329 Zinc finger protein 703 OS=Homo sapiens OX=9606 GN=ZNF703 PE=1 SV=1 8.23 2464.5 - 172744 - - - 0.6532 - 2.634 0.61 - 67.7 1 2 0 0.0018 29 0 0 0 2.68E+07 1.24E+07 - - - 7.5686 0.9996 221125_WJC_METTL3_EV_vs_WT_F10.12758.12758.3 7.06E-08 Sep-96 R.NKEPPAPAQQLQPQPVAVQGPEPAR.V "sp|Q9HC07|TM165_HUMAN,tr|D6RBL0|D6RBL0_HUMAN,tr|D6RD79|D6RD79_HUMAN" 3 2646.3878 1.44 144063 12758 3 2646.395947 883.1365 Transmembrane protein 165 OS=Homo sapiens OX=9606 GN=TMEM165 PE=1 SV=1 6.14 2465.1 - 138940 - - - 3.0793 - 2.465 0.559 - 48.2 1 2 1 0.0081 25 0 0 0 1.03E+08 7.17E+07 - - - 6.8457 0.9999 221125_WJC_METTL3_EV_vs_WT_F10.12763.12763.3 9.99E-09 Dec-96 R.NK[136.11]EPPAPAQQLQPQPVAVQGPEPAR[166.11].V "sp|Q9HC07|TM165_HUMAN,tr|D6RBL0|D6RBL0_HUMAN,tr|D6RD79|D6RD79_HUMAN" 3 2664.4103 1.44 144066 12763 3 2664.41101 889.144 Transmembrane protein 165 OS=Homo sapiens OX=9606 GN=TMEM165 PE=1 SV=1 6.14 2465.8 - 176191 - - - 0.2785 - 2.771 0.645 - 79.1 1 2 1 0.0007 25 0 0 0 1.03E+08 7.17E+07 - - - 8.0757 1 221125_WJC_METTL3_EV_vs_WT_F10.12766.12766.4 5.80E-10 16/126 R.ENYSSYSSFSSPHMKPAPVGSR.G sp|Q5BKZ1|ZN326_HUMAN 1 2414.0961 1.12 144068 12766 4 2414.095539 604.5313 DBIRD complex subunit ZNF326 OS=Homo sapiens OX=9606 GN=ZNF326 PE=1 SV=2 8.6 2466.1 - 238365 - - - -0.2361 - 2.961 0.608 - 191.6 1 2 0 -0.0006 22 0 0 0 6.94E+06 6.22E+06 - - - 4.8731 1 221125_WJC_METTL3_EV_vs_WT_F10.12772.12772.4 0.000184 14/150 K.VLVPGIPGHHAAIK[136.11]PAPPQTEQVESK[136.11].R sp|Q15061|WDR43_HUMAN 1 2715.5043 1.27 144072 12772 4 2715.504585 679.8833 WD repeat-containing protein 43 OS=Homo sapiens OX=9606 GN=WDR43 PE=1 SV=3 6.9 2466.9 - 249995 - - - 0.1105 - 2.541 0.56 - 67.7 1 2 0 0.0003 26 0 0 0 2.83E+07 2.22E+07 - - - 4.3943 0.9999 221125_WJC_METTL3_EV_vs_WT_F10.12773.12773.3 0.000191 9/104 R.GTEAGQVGEPGIPTGEAGPSC[160.03]SSASDK.L sp|O15355|PPM1G_HUMAN 1 2545.1238 0.85 144073 12773 3 2545.118764 849.3819 Protein phosphatase 1G OS=Homo sapiens OX=9606 GN=PPM1G PE=1 SV=1 4 2467.1 - 189955 - - - -1.9944 - 2.354 0.545 - 63.8 1 2 0 -0.0051 27 0 0 0 4.92E+06 5.81E+06 - - - 6.5844 0.9626 221125_WJC_METTL3_EV_vs_WT_F10.12775.12775.3 0.00401 6/112 R.VPSAAC[160.03]PPFPPHGAPVSASSSSSSPGGSR[166.11].G sp|Q9H7S9|ZN703_HUMAN 1 2744.2852 2.14 144075 12775 3 2745.286972 915.769 Zinc finger protein 703 OS=Homo sapiens OX=9606 GN=ZNF703 PE=1 SV=1 8.23 2467.3 - 121480 - - - 365.0404 - 1.39 0.358 - 12 1 2 0 1.0018 29 0 0 0 2.77E+07 1.29E+07 - - - 3.0115 0.9999 221125_WJC_METTL3_EV_vs_WT_F10.12778.12778.3 3.03E-06 Dec-64 R.ADTQTYQPYNK[136.11]DWIK[136.11]EK[136.11].L sp|P84090|ERH_HUMAN 1 2151.0699 2.58 144076 12778 3 2151.06961 718.0306 Enhancer of rudimentary homolog OS=Homo sapiens OX=9606 GN=ERH PE=1 SV=1 6.16 2467.7 - 621640 - - - -0.1278 - 2.735 0.503 - 177.3 1 2 2 -0.0003 17 0 0 0 4.94E+07 1.92E+07 - - - 6.6897 0.9999 221125_WJC_METTL3_EV_vs_WT_F10.12780.12780.4 5.62E-05 13/150 K.VLVPGIPGHHAAIKPAPPQTEQVESK.R sp|Q15061|WDR43_HUMAN 1 2699.4759 1.27 144078 12780 4 2699.477678 675.8762 WD repeat-containing protein 43 OS=Homo sapiens OX=9606 GN=WDR43 PE=1 SV=3 6.9 2468 - 371254 - - - 0.6642 - 2.513 0.421 - 58.9 1 2 0 0.0018 26 0 0 0 2.83E+07 2.22E+07 - - - 3.1806 0.9997 221125_WJC_METTL3_EV_vs_WT_F10.12785.12785.3 0.000812 6/108 R.VTEAPC[160.03]YPGAPSTEASGQTGPQEPTSAR.A sp|P40222|TXLNA_HUMAN 1 2845.2825 1.37 144081 12785 3 2845.27225 949.4348 Alpha-taxilin OS=Homo sapiens OX=9606 GN=TXLNA PE=1 SV=3 4.25 2468.7 - 79774.3 - - - -3.5905 - 1.666 0.557 - 21.2 1 2 0 -0.0102 28 0 0 0 1.37E+07 1.00E+07 - - - 5.9215 0.9999 221125_WJC_METTL3_EV_vs_WT_F10.12790.12790.3 2.94E-08 16/64 R.ADTQTYQPYNKDWIKEK.L sp|P84090|ERH_HUMAN 1 2127.0273 2.58 144084 12790 3 2127.029463 710.0164 Enhancer of rudimentary homolog OS=Homo sapiens OX=9606 GN=ERH PE=1 SV=1 6.16 2469.3 - 2.23E+06 - - - 1.0244 - 3.303 0.512 - 261.2 1 2 2 0.0022 17 0 0 0 4.94E+07 1.92E+07 - - - 7.2662 0.9999 221125_WJC_METTL3_EV_vs_WT_F10.12797.12797.4 1.99E-07 24/144 R.NKEPPAPAQQLQPQPVAVQGPEPAR.V "sp|Q9HC07|TM165_HUMAN,tr|D6RBL0|D6RBL0_HUMAN,tr|D6RD79|D6RD79_HUMAN" 3 2646.3878 1.46 144088 12797 4 2646.392368 662.6042 Transmembrane protein 165 OS=Homo sapiens OX=9606 GN=TMEM165 PE=1 SV=1 6.14 2470.2 - 514771 - - - 1.7269 - 3.591 0.556 - 322.3 1 2 1 0.0046 25 0 0 0 2.09E+07 1.43E+07 - - - 4.4709 0.9999 221125_WJC_METTL3_EV_vs_WT_F10.12798.12798.4 1.41E-07 24/144 R.NK[136.11]EPPAPAQQLQPQPVAVQGPEPAR[166.11].V "sp|Q9HC07|TM165_HUMAN,tr|D6RBL0|D6RBL0_HUMAN,tr|D6RD79|D6RD79_HUMAN" 3 2664.4103 1.46 144089 12798 4 2664.414769 667.1098 Transmembrane protein 165 OS=Homo sapiens OX=9606 GN=TMEM165 PE=1 SV=1 6.14 2470.3 - 315656 - - - 1.6893 - 3.69 0.604 - 307.4 1 2 1 0.0045 25 0 0 0 2.04E+07 1.40E+07 - - - 4.8973 1 221125_WJC_METTL3_EV_vs_WT_F10.12806.12806.3 6.39E-09 18/92 R.QRPTLLPATGSTPQPGSSQQIQQR.L "sp|Q96KQ4|ASPP1_HUMAN,tr|H0YJL1|H0YJL1_HUMAN,tr|A0A3B3ISJ2|A0A3B3ISJ2_HUMAN" 3 2575.3467 3.89 144095 12806 3 2575.348364 859.4562 Apoptosis-stimulating of p53 protein 1 OS=Homo sapiens OX=9606 GN=PPP1R13B PE=1 SV=3 12 2471.4 - 356511 - - - 0.6609 - 3.065 0.661 - 210.8 1 2 0 0.0017 24 0 0 0 1.04E+07 2.67E+06 - - - 8.5104 1 221125_WJC_METTL3_EV_vs_WT_F10.12813.12813.3 1.89E-11 12/108 R.VTEAPC[160.03]YPGAPSTEASGQTGPQEPTSAR[166.11].A sp|P40222|TXLNA_HUMAN 1 2855.2907 1.37 144099 12813 3 2855.29753 952.7709 Alpha-taxilin OS=Homo sapiens OX=9606 GN=TXLNA PE=1 SV=3 4.25 2472.3 - 204934 - - - 2.3794 - 2.856 0.659 - 90.2 1 2 0 0.0068 28 0 0 0 1.37E+07 1.00E+07 - - - 8.2997 1 221125_WJC_METTL3_EV_vs_WT_F10.12821.12821.3 6.41E-12 21/76 K.RQTSGGPVDASSEYQQELER.E "sp|P18859|ATP5J_HUMAN,tr|A8MUH2|A8MUH2_HUMAN" 2 2236.0356 1.27 144105 12821 3 2236.056104 746.3525 "ATP synthase-coupling factor 6, mitochondrial OS=Homo sapiens OX=9606 GN=ATP5PF PE=1 SV=1" 4.41 2473.3 - 252981 - - - 9.1622 - 4.002 0.653 - 678 1 2 0 0.0205 20 0 0 0 5.46E+06 4.30E+06 - - - 9.179 0.9969 221125_WJC_METTL3_EV_vs_WT_F10.12823.12823.3 0.122 Sep-44 K.QQHVIETLIGKK.Q "sp|P48643|TCPE_HUMAN,tr|E9PCA1|E9PCA1_HUMAN,tr|B7ZAR1|B7ZAR1_HUMAN,tr|E7ENZ3|E7ENZ3_HUMAN" 4 1392.8089 0.51 144107 12823 3 1392.810791 465.2769 T-complex protein 1 subunit epsilon OS=Homo sapiens OX=9606 GN=CCT5 PE=1 SV=1 8.6 2473.6 - 168014 - - - 1.3584 - 1.4 0.291 - 89 1 2 0 0.0019 12 0 0 0 5.45E+06 1.06E+07 - - - 2.7165 1 221125_WJC_METTL3_EV_vs_WT_F10.12824.12824.3 5.73E-09 14/92 R.QR[166.11]PTLLPATGSTPQPGSSQQIQQR[166.11].L "sp|Q96KQ4|ASPP1_HUMAN,tr|H0YJL1|H0YJL1_HUMAN,tr|A0A3B3ISJ2|A0A3B3ISJ2_HUMAN" 3 2595.3632 3.89 144108 12824 3 2595.370321 866.1283 Apoptosis-stimulating of p53 protein 1 OS=Homo sapiens OX=9606 GN=PPP1R13B PE=1 SV=3 12 2473.7 - 139752 - - - 2.743 - 3.046 0.619 - 113.8 1 2 0 0.0071 24 0 0 0 1.04E+07 2.67E+06 - - - 8.0262 0.9985 221125_WJC_METTL3_EV_vs_WT_F10.12833.12833.4 8.50E-06 11/132 K.NNFTC[160.03]VAC[160.03]HPTEDC[160.03]IASGHMDGK[136.11].L sp|Q8IWA0|WDR75_HUMAN 1 2628.0705 1.33 144115 12833 4 2629.078833 658.0249 WD repeat-containing protein 75 OS=Homo sapiens OX=9606 GN=WDR75 PE=1 SV=1 5.21 2474.9 - 168651 - - - 383.6735 - 2.118 0.553 - 57.5 1 2 0 1.0083 23 0 0 0 5.63E+06 4.25E+06 - - - 4.0032 1 221125_WJC_METTL3_EV_vs_WT_F10.12841.12841.3 1.95E-11 22/76 K.R[166.11]QTSGGPVDASSEYQQELER[166.11].E "sp|P18859|ATP5J_HUMAN,tr|A8MUH2|A8MUH2_HUMAN" 2 2256.0522 1.27 144121 12841 3 2256.057006 753.0247 "ATP synthase-coupling factor 6, mitochondrial OS=Homo sapiens OX=9606 GN=ATP5PF PE=1 SV=1" 4.41 2476.1 - 266194 - - - 2.1493 - 3.978 0.724 - 703.4 1 2 0 0.0048 20 0 0 0 5.46E+06 4.30E+06 - - - 9.9603 0.9951 221125_WJC_METTL3_EV_vs_WT_F10.12842.12842.2 0.623 16-Jul K.LSDGVAVLK[136.11].V "sp|P10809|CH60_HUMAN,tr|A0A7I2V2X6|A0A7I2V2X6_HUMAN,tr|A0A7I2YQK6|A0A7I2YQK6_HUMAN,tr|A0A7I2V599|A0A7I2V599_HUMAN" 4 908.5422 1.1 144122 12842 2 908.543148 455.2784 "60 kDa heat shock protein, mitochondrial OS=Homo sapiens OX=9606 GN=HSPD1 PE=1 SV=2" 5.84 2476.2 - 228734 - - - 1.0071 - 1.391 0.179 - 80.7 1 2 0 0.0009 9 0 0 0 3.74E+06 3.39E+06 - - - 1.3176 0.9873 221125_WJC_METTL3_EV_vs_WT_F10.12844.12844.3 0.144 Jul-36 R.K[136.11]QDSGHLDLR[166.11].N "sp|Q86U44|MTA70_HUMAN,tr|B4E349|B4E349_HUMAN,tr|F5H6D8|F5H6D8_HUMAN,tr|B4DTN4|B4DTN4_HUMAN" 4 1185.6221 0.02 144124 12844 3 1185.621246 396.2146 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 6.75 2476.5 - 131976 - - - -0.7245 - 1.383 0.195 - 74.5 1 2 0 -0.0009 10 0 0 0 1.89E+05 8.57E+06 - - - 1.6608 0.9998 221125_WJC_METTL3_EV_vs_WT_F10.12845.12845.4 7.35E-05 Sep-90 R.RDNEVDGQDYHFVVSR.E "sp|Q92796|DLG3_HUMAN,tr|Q5JUW8|Q5JUW8_HUMAN" 2 1934.8871 0.68 144125 12845 4 1934.894212 484.7291 Disks large homolog 3 OS=Homo sapiens OX=9606 GN=DLG3 PE=1 SV=2 4.66 2476.6 - 91969.3 - - - 3.6741 - 1.945 0.49 - 75.2 1 2 0 0.0071 16 0 0 0 9.02E+05 1.33E+06 - - - 3.7233 1 221125_WJC_METTL3_EV_vs_WT_F10.12850.12850.4 2.38E-11 33/150 R.MSGEC[160.03]APNVSVSVSTSHTTISGGGSR.G sp|P04264|K2C1_HUMAN 1 2564.1595 129 144128 12850 4 2564.161724 642.0472 "Keratin, type II cytoskeletal 1 OS=Homo sapiens OX=9606 GN=KRT1 PE=1 SV=6" 6.5 2477.3 - 693091 - - - 0.8619 - 5.234 0.712 - 868.8 1 2 0 0.0022 26 0 0 0 2.00E+07 1.55E+05 - - - 5.9447 0.9985 221125_WJC_METTL3_EV_vs_WT_F10.12863.12863.4 0.0707 13/78 K.DRLLASTLVHSVKK.E "sp|Q9NYF8|BCLF1_HUMAN,tr|E9PKI6|E9PKI6_HUMAN,tr|A0A1W2PQ43|A0A1W2PQ43_HUMAN,tr|E9PK91|E9PK91_HUMAN,tr|E9PJA7|E9PJA7_HUMAN,tr|E9PK09|E9PK09_HUMAN,tr|E9PQN2|E9PQN2_HUMAN" 7 1565.9253 1.22 144139 12863 4 1565.929256 392.4886 Bcl-2-associated transcription factor 1 OS=Homo sapiens OX=9606 GN=BCLAF1 PE=1 SV=2 9.99 2479 - 134885 - - - 2.5097 - 2.461 0.384 - 179.1 1 2 1 0.0039 14 0 0 0 2.99E+06 2.44E+06 - - - 2.895 1 221125_WJC_METTL3_EV_vs_WT_F10.12864.12864.3 1.78E-10 13/88 K.NSVHEQEAINSDPELSNC[160.03]ENFQK.T sp|Q8IX90|SKA3_HUMAN 1 2688.1722 2.48 144140 12864 3 2688.16551 897.0647 Spindle and kinetochore-associated protein 3 OS=Homo sapiens OX=9606 GN=SKA3 PE=1 SV=2 4.25 2479.1 - 114946 - - - -2.4842 - 2.939 0.731 - 177.7 1 2 0 -0.0067 23 0 0 0 2.11E+06 8.50E+05 - - - 9.2172 1 221125_WJC_METTL3_EV_vs_WT_F10.12870.12870.2 3.57E-15 22/50 R.MSGEC[160.03]APNVSVSVSTSHTTISGGGSR.G sp|P04264|K2C1_HUMAN 1 2564.1595 999 144144 12870 2 2564.156879 1283.087 "Keratin, type II cytoskeletal 1 OS=Homo sapiens OX=9606 GN=KRT1 PE=1 SV=6" 6.5 2479.9 - 349880 - - - -1.0276 - 4.307 0.802 - 1158 1 2 0 -0.0026 26 0 0 0 6.85E+06 0.00E+00 - - - 8.5538 0.9244 221125_WJC_METTL3_EV_vs_WT_F10.12878.12878.4 1.38E-05 13/90 Y.RADTQTYQPYNKDWIK.E sp|P84090|ERH_HUMAN 1 2025.9908 1.6 144150 12878 4 2025.985511 507.505 Enhancer of rudimentary homolog OS=Homo sapiens OX=9606 GN=ERH PE=1 SV=1 8.43 2481 - 559710 - - - -2.6298 - 2.451 0.441 - 162.4 1 1 1 -0.0053 16 0 0 0 8.23E+06 5.16E+06 - - - 3.3788 0.9974 221125_WJC_METTL3_EV_vs_WT_F10.12879.12879.4 0.000147 10/102 R.DTLLALHQHGHSGPFESK[136.11].F sp|Q7Z5L9|I2BP2_HUMAN 1 1980.9897 1.46 144151 12879 4 1980.987712 496.2547 Interferon regulatory factor 2-binding protein 2 OS=Homo sapiens OX=9606 GN=IRF2BP2 PE=1 SV=2 6.26 2481.1 - 515914 - - - -1.0157 - 2.476 0.271 - 59.5 2 2 0 -0.002 18 0 0 0 9.88E+07 6.76E+07 - - - 1.6654 0.9999 221125_WJC_METTL3_EV_vs_WT_F10.12880.12880.4 2.59E-05 Nov-78 K.DR[166.11]LLASTLVHSVK[136.11]K[136.11].E "sp|Q9NYF8|BCLF1_HUMAN,tr|E9PKI6|E9PKI6_HUMAN,tr|A0A1W2PQ43|A0A1W2PQ43_HUMAN,tr|E9PK91|E9PK91_HUMAN,tr|E9PJA7|E9PJA7_HUMAN,tr|E9PK09|E9PK09_HUMAN,tr|E9PQN2|E9PQN2_HUMAN" 7 1591.962 1.22 144152 12880 4 1591.962041 398.9978 Bcl-2-associated transcription factor 1 OS=Homo sapiens OX=9606 GN=BCLAF1 PE=1 SV=2 9.99 2481.2 - 189875 - - - 0.0283 - 2.118 0.559 - 138.9 1 2 1 0 14 0 0 0 2.99E+06 2.44E+06 - - - 4.3647 1 221125_WJC_METTL3_EV_vs_WT_F10.12889.12889.4 1.01E-08 15/102 R.DTLLALHQHGHSGPFESK.F sp|Q7Z5L9|I2BP2_HUMAN 1 1972.9755 1.46 144158 12889 4 1972.975281 494.2512 Interferon regulatory factor 2-binding protein 2 OS=Homo sapiens OX=9606 GN=IRF2BP2 PE=1 SV=2 6.26 2482.3 - 435524 - - - -0.1232 - 3.253 0.52 - 169.9 1 2 0 -0.0002 18 0 0 0 9.87E+07 6.76E+07 - - - 4.1561 0.9999 221125_WJC_METTL3_EV_vs_WT_F10.12898.12898.3 6.52E-07 19/68 K.K[136.11]GESQTDIEITR[166.11]EEDFTR[166.11].L "sp|P49368|TCPG_HUMAN,tr|B4DUR8|B4DUR8_HUMAN" 2 2181.0544 0.22 144165 12898 3 2181.05498 728.0254 T-complex protein 1 subunit gamma OS=Homo sapiens OX=9606 GN=CCT3 PE=1 SV=4 4.36 2483.5 - 686619 - - - 0.2678 - 2.802 0.584 - 314.4 1 2 1 0.0006 18 0 0 0 2.38E+07 1.06E+08 - - - 7.6165 0.9999 221125_WJC_METTL3_EV_vs_WT_F10.12906.12906.4 1.36E-09 22/102 K.K[136.11]GESQTDIEITR[166.11]EEDFTR[166.11].L "sp|P49368|TCPG_HUMAN,tr|B4DUR8|B4DUR8_HUMAN" 2 2181.0544 0.23 144171 12906 4 2181.05466 546.2709 T-complex protein 1 subunit gamma OS=Homo sapiens OX=9606 GN=CCT3 PE=1 SV=4 4.36 2484.6 - 3.91E+06 - - - 0.121 - 3.12 0.556 - 440.4 1 2 1 0.0003 18 0 0 0 4.62E+07 1.99E+08 - - - 4.4551 0.9972 221125_WJC_METTL3_EV_vs_WT_F10.12912.12912.4 0.0787 9/144 K.VEELPPKPLEQGDETPKPPKPDPLK.L sp|P48634|PRC2A_HUMAN 1 2777.4851 2.09 144176 12912 4 2777.489527 695.3786 Protein PRRC2A OS=Homo sapiens OX=9606 GN=PRRC2A PE=1 SV=3 4.66 2485.3 - 233192 - - - 1.5896 - 1.804 0.264 - 39 1 2 0 0.0044 25 0 0 0 4.79E+06 2.29E+06 - - - 1.7103 0.9999 221125_WJC_METTL3_EV_vs_WT_F10.12914.12914.3 1.65E-06 21/68 K.KGESQTDIEITREEDFTR.L "sp|P49368|TCPG_HUMAN,tr|B4DUR8|B4DUR8_HUMAN" 2 2153.0237 0.22 144177 12914 3 2153.023356 718.6818 T-complex protein 1 subunit gamma OS=Homo sapiens OX=9606 GN=CCT3 PE=1 SV=4 4.36 2485.6 - 805148 - - - -0.1393 - 3.192 0.536 - 358.3 1 2 1 -0.0003 18 0 0 0 2.38E+07 1.06E+08 - - - 7.4059 0.9999 221125_WJC_METTL3_EV_vs_WT_F10.12916.12916.4 5.58E-05 21/102 K.KGESQTDIEITREEDFTR.L "sp|P49368|TCPG_HUMAN,tr|B4DUR8|B4DUR8_HUMAN" 2 2153.0237 0.23 144179 12916 4 2153.026569 539.2632 T-complex protein 1 subunit gamma OS=Homo sapiens OX=9606 GN=CCT3 PE=1 SV=4 4.36 2485.8 - 1.25E+06 - - - 1.353 - 3.798 0.514 - 326 1 2 1 0.0029 18 0 0 0 4.54E+07 1.98E+08 - - - 4.1562 1 221125_WJC_METTL3_EV_vs_WT_F10.12924.12924.4 1.52E-10 23/132 A.FASSLVSGLNSSASEPAK[136.11]EPAK[136.11]K[136.11].S "sp|Q86U44|MTA70_HUMAN,tr|F5H6D8|F5H6D8_HUMAN,tr|H0YFV6|H0YFV6_HUMAN,tr|B4DTN4|B4DTN4_HUMAN" 4 2328.2387 0 144185 12924 4 2328.239457 583.067 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 8.5 2486.8 - 1.41E+06 - - - 0.3075 - 4.143 0.615 - 329.7 1 1 1 0.0007 23 0 0 0 4.50E+06 4.86E+09 - - - 5.0393 0.9744 221125_WJC_METTL3_EV_vs_WT_F10.12926.12926.3 8.52E-08 17/88 A.FASSLVSGLNSSASEPAK[136.11]EPAK[136.11]K[136.11].S "sp|Q86U44|MTA70_HUMAN,tr|F5H6D8|F5H6D8_HUMAN,tr|H0YFV6|H0YFV6_HUMAN,tr|B4DTN4|B4DTN4_HUMAN" 4 2328.2387 0.001 144187 12926 3 2328.243966 777.0869 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 8.5 2487 - 359131 - - - 2.2442 - 2.609 0.54 - 178.5 1 1 1 0.0052 23 0 0 0 0.00E+00 1.32E+09 - - - 6.8087 1 221125_WJC_METTL3_EV_vs_WT_F10.12928.12928.4 5.88E-06 14/108 R.ALVDHENVISC[160.03]PHLGASTK.E "sp|O43175|SERA_HUMAN,tr|A0A286YF78|A0A286YF78_HUMAN,tr|A0A2C9F2M7|A0A2C9F2M7_HUMAN,tr|A0A286YF22|A0A286YF22_HUMAN,tr|A0A286YFL2|A0A286YFL2_HUMAN,tr|A0A286YFA2|A0A286YFA2_HUMAN" 6 2047.0157 0.94 144189 12928 4 2047.015669 512.7612 D-3-phosphoglycerate dehydrogenase OS=Homo sapiens OX=9606 GN=PHGDH PE=1 SV=4 5.99 2487.3 - 266230 - - - -0.0024 - 3.058 0.489 - 103.6 1 2 0 0 19 0 0 0 6.44E+06 6.87E+06 - - - 3.8604 0.9996 221125_WJC_METTL3_EV_vs_WT_F10.12934.12934.4 1.40E-06 14/102 R.TGQPMIHIYLDK[136.11]ETGK[136.11]PK[136.11].G "sp|Q01844|EWS_HUMAN,tr|B0QYK0|B0QYK0_HUMAN,tr|H7BY36|H7BY36_HUMAN,tr|A0A0D9SFL3|A0A0D9SFL3_HUMAN,tr|C9JGE3|C9JGE3_HUMAN" 5 2079.1249 0.62 144192 12934 4 2079.132162 520.7885 RNA-binding protein EWS OS=Homo sapiens OX=9606 GN=EWSR1 PE=1 SV=1 8.13 2488.1 - 317675 - - - 3.4943 - 3.177 0.527 - 116 1 2 1 0.0073 18 0 0 0 4.37E+08 6.99E+08 - - - 4.207 0.9859 221125_WJC_METTL3_EV_vs_WT_F10.12935.12935.3 0.103 Dec-68 R.DTLLALHQHGHSGPFESK.F sp|Q7Z5L9|I2BP2_HUMAN 1 1972.9755 1.74 144193 12935 3 1972.979026 658.6658 Interferon regulatory factor 2-binding protein 2 OS=Homo sapiens OX=9606 GN=IRF2BP2 PE=1 SV=2 6.26 2488.2 - 235246 - - - 1.775 - 1.625 0.194 - 39.4 1 2 0 0.0035 18 0 0 0 2.87E+07 1.65E+07 - - - 1.9109 0.9999 221125_WJC_METTL3_EV_vs_WT_F10.12938.12938.3 0.00103 Nov-48 R.IQFKPDDGISPER.A sp|Q96I24|FUBP3_HUMAN 1 1500.7573 0.74 144196 12938 3 1500.75801 501.2597 Far upstream element-binding protein 3 OS=Homo sapiens OX=9606 GN=FUBP3 PE=1 SV=2 4.56 2488.6 - 220570 - - - 0.5017 - 2.363 0.388 - 131.3 1 2 0 0.0008 13 0 0 0 6.56E+06 8.82E+06 - - - 5.1971 0.9999 221125_WJC_METTL3_EV_vs_WT_F10.12943.12943.3 3.00E-07 Dec-64 R.C[160.03]R[166.11]NPNK[136.11]LDINTLTGEER[166.11].V sp|Q9P2D1|CHD7_HUMAN 1 2057.0318 1.47 144199 12943 3 2057.035576 686.6846 Chromodomain-helicase-DNA-binding protein 7 OS=Homo sapiens OX=9606 GN=CHD7 PE=1 SV=3 6.17 2489.2 - 253863 - - - 1.8225 - 2.864 0.545 - 150.1 1 2 2 0.0037 17 0 0 0 1.41E+07 9.56E+06 - - - 7.2734 0.9999 221125_WJC_METTL3_EV_vs_WT_F10.12966.12966.4 0.000105 Dec-90 R.QATINIGTIGHVAHGK[136.11].S "sp|Q2VIR3|IF2GL_HUMAN,sp|P41091|IF2G_HUMAN,tr|H7BZU1|H7BZU1_HUMAN" 3 1623.8936 0.94 144213 12966 4 1623.890411 406.9807 Eukaryotic translation initiation factor 2 subunit 3B OS=Homo sapiens OX=9606 GN=EIF2S3B PE=2 SV=2 8.76 2492.3 - 241770 - - - -1.9872 - 2.568 0.46 - 128.7 1 2 0 -0.0032 16 0 0 0 5.61E+06 5.97E+06 - - - 3.5612 1 221125_WJC_METTL3_EV_vs_WT_F10.12967.12967.3 1.28E-07 16/68 R.DTLLALHQHGHSGPFESK[136.11].F sp|Q7Z5L9|I2BP2_HUMAN 1 1980.9897 1.74 144214 12967 3 1980.988619 661.3372 Interferon regulatory factor 2-binding protein 2 OS=Homo sapiens OX=9606 GN=IRF2BP2 PE=1 SV=2 6.26 2492.4 - 343103 - - - -0.5578 - 3.17 0.488 - 327.1 1 2 0 -0.0011 18 0 0 0 2.87E+07 1.65E+07 - - - 6.8533 1 221125_WJC_METTL3_EV_vs_WT_F10.12970.12970.3 4.62E-10 19/100 R.MSGEC[160.03]APNVSVSVSTSHTTISGGGSR.G sp|P04264|K2C1_HUMAN 1 2564.1595 999 144216 12970 3 2564.157745 855.7271 "Keratin, type II cytoskeletal 1 OS=Homo sapiens OX=9606 GN=KRT1 PE=1 SV=6" 6.5 2492.7 - 579573 - - - -0.6899 - 3.873 0.726 - 323.4 1 2 0 -0.0018 26 0 0 0 1.16E+07 0.00E+00 - - - 9.7488 0.9998 221125_WJC_METTL3_EV_vs_WT_F10.12972.12972.4 1.87E-07 17/102 R.TGQPMIHIYLDKETGKPK.G "sp|Q01844|EWS_HUMAN,tr|B0QYK0|B0QYK0_HUMAN,tr|H7BY36|H7BY36_HUMAN,tr|A0A0D9SFL3|A0A0D9SFL3_HUMAN,tr|C9JGE3|C9JGE3_HUMAN" 5 2055.0823 0.62 144217 12972 4 2055.085718 514.7779 RNA-binding protein EWS OS=Homo sapiens OX=9606 GN=EWSR1 PE=1 SV=1 8.13 2493 - 512283 - - - 1.6647 - 3.235 0.491 - 193.4 1 2 1 0.0034 18 0 0 0 4.37E+08 6.99E+08 - - - 3.9009 0.9999 221125_WJC_METTL3_EV_vs_WT_F10.12977.12977.4 6.81E-06 Oct-84 K.HSFDTFSHQRPC[160.03]LLK.S "sp|P51648|AL3A2_HUMAN,tr|A0A5F9ZHN9|A0A5F9ZHN9_HUMAN,tr|J3KTD9|J3KTD9_HUMAN,tr|A0A5K1VW72|A0A5K1VW72_HUMAN,tr|A0A5F9ZGX4|A0A5F9ZGX4_HUMAN,tr|A0A5F9ZHP6|A0A5F9ZHP6_HUMAN" 6 1871.9101 0.91 144220 12977 4 1871.908041 468.9848 Aldehyde dehydrogenase family 3 member A2 OS=Homo sapiens OX=9606 GN=ALDH3A2 PE=1 SV=1 8.24 2493.6 - 448047 - - - -1.093 - 2.276 0.469 - 91.3 1 2 0 -0.002 15 0 0 0 5.84E+06 6.42E+06 - - - 3.6019 0.9997 221125_WJC_METTL3_EV_vs_WT_F10.12978.12978.2 0.00199 22-Nov R.ALEEANADLEVK.L "sp|P02533|K1C14_HUMAN,sp|P08779|K1C16_HUMAN,sp|P19012|K1C15_HUMAN,sp|P13646|K1C13_HUMAN,tr|K7EMD9|K7EMD9_HUMAN,tr|K7ERE3|K7ERE3_HUMAN" 6 1300.6511 25.42 144221 12978 2 1300.652342 651.3328 "Keratin, type I cytoskeletal 14 OS=Homo sapiens OX=9606 GN=KRT14 PE=1 SV=4" 4 2493.8 - 260421 - - - 0.9849 - 2.425 0.319 - 323.5 1 2 0 0.0013 12 0 0 0 6.28E+06 2.47E+05 - - - 3.7275 1 221125_WJC_METTL3_EV_vs_WT_F10.12979.12979.2 7.08E-11 16/26 L.NSSASEPAK[136.11]EPAK[136.11]K[136.11].S "sp|Q86U44|MTA70_HUMAN,tr|F5H6D8|F5H6D8_HUMAN,tr|H0YFV6|H0YFV6_HUMAN,tr|B4DTN4|B4DTN4_HUMAN" 4 1466.7791 0.001 144222 12979 2 1466.777305 734.3968 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 8.5 2493.9 - 426297 - - - -1.2388 - 2.735 0.664 - 758.1 1 1 1 -0.0018 14 0 0 0 0.00E+00 3.49E+07 - - - 6.4696 0.9994 221125_WJC_METTL3_EV_vs_WT_F10.12984.12984.3 0.00414 Sep-60 R.QATINIGTIGHVAHGK[136.11].S "sp|Q2VIR3|IF2GL_HUMAN,sp|P41091|IF2G_HUMAN,tr|H7BZU1|H7BZU1_HUMAN" 3 1623.8936 0.95 144225 12984 3 1623.892508 542.3052 Eukaryotic translation initiation factor 2 subunit 3B OS=Homo sapiens OX=9606 GN=EIF2S3B PE=2 SV=2 8.76 2494.4 - 165948 - - - -0.6959 - 1.939 0.312 - 71.2 1 2 0 -0.0011 16 0 0 0 3.32E+06 3.49E+06 - - - 3.7172 1 221125_WJC_METTL3_EV_vs_WT_F10.12985.12985.2 1.38E-11 17/32 V.SGLNSSASEPAK[136.11]EPAK[136.11]K[136.11].S "sp|Q86U44|MTA70_HUMAN,tr|F5H6D8|F5H6D8_HUMAN,tr|H0YFV6|H0YFV6_HUMAN,tr|B4DTN4|B4DTN4_HUMAN" 4 1723.9167 0.001 144226 12985 2 1723.914171 862.9656 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 8.22 2494.6 - 238278 - - - -1.4542 - 3.191 0.708 - 848.5 1 1 1 -0.0025 17 0 0 0 0.00E+00 9.74E+06 - - - 7.1222 1 221125_WJC_METTL3_EV_vs_WT_F10.12989.12989.3 1.35E-14 26/112 R.VPSAAC[160.03]PPFPPHGAPVSASSSSSSPGGSR.G sp|Q9H7S9|ZN703_HUMAN 1 2734.2769 2.47 144228 12989 3 2734.276226 912.4329 Zinc finger protein 703 OS=Homo sapiens OX=9606 GN=ZNF703 PE=1 SV=1 8.23 2495.1 - 883334 - - - -0.2564 - 4.195 0.732 - 404.7 1 2 0 -0.0007 29 0 0 0 8.86E+07 3.59E+07 - - - 9.9998 1 221125_WJC_METTL3_EV_vs_WT_F10.12991.12991.3 3.96E-12 20/96 R.NKEPPAPAQQLQPQPVAVQGPEPAR.V "sp|Q9HC07|TM165_HUMAN,tr|D6RBL0|D6RBL0_HUMAN,tr|D6RD79|D6RD79_HUMAN" 3 2646.3878 1.57 144229 12991 3 2646.388454 883.1365 Transmembrane protein 165 OS=Homo sapiens OX=9606 GN=TMEM165 PE=1 SV=1 6.14 2495.5 - 945503 - - - 0.2479 - 4.272 0.627 - 275.8 1 2 1 0.0007 25 0 0 0 5.95E+07 3.79E+07 - - - 8.871 1 221125_WJC_METTL3_EV_vs_WT_F10.12994.12994.4 0.000367 20/156 R.SPR[166.11]PTSAPAITQGQVAEGGVLDASAK[136.11]K[136.11].T "sp|P11171|EPB41_HUMAN,tr|A0A2R8Y6D0|A0A2R8Y6D0_HUMAN,tr|A0A2R8YFR9|A0A2R8YFR9_HUMAN,tr|A0A2R8Y420|A0A2R8Y420_HUMAN,tr|A0A2R8YCW8|A0A2R8YCW8_HUMAN,tr|A0A2R8Y7N0|A0A2R8Y7N0_HUMAN,tr|A0A3B3ITP0|A0A3B3ITP0_HUMAN,tr|A0A2R8Y5C8|A0A2R8Y5C8_HUMAN,tr|A0A3B3IU06|A0A3B3IU06_HUMAN,tr|A0A2R8Y5G2|A0A2R8Y5G2_HUMAN,tr|A0A1B0GWG0|A0A1B0GWG0_HUMAN,tr|A0A2U3TZH6|A0A2U3TZH6_HUMAN,tr|A0A3B3IUD6|A0A3B3IUD6_HUMAN,tr|A0A2R8Y7Y3|A0A2R8Y7Y3_HUMAN,tr|A0A2R8Y570|A0A2R8Y570_HUMAN,tr|A0A2R8Y6G5|A0A2R8Y6G5_HUMAN,tr|A0A2R8Y5Z6|A0A2R8Y5Z6_HUMAN,tr|A0A2R8YD30|A0A2R8YD30_HUMAN,tr|A0A2R8Y4N6|A0A2R8Y4N6_HUMAN" 19 2661.4296 1.66 144231 12994 4 2661.425198 666.3647 Protein 4.1 OS=Homo sapiens OX=9606 GN=EPB41 PE=1 SV=4 8.31 2495.8 - 306559 - - - -1.6589 - 3.341 0.565 - 250.1 1 2 0 -0.0044 27 0 0 0 8.58E+06 5.18E+06 - - - 4.52 0.9997 221125_WJC_METTL3_EV_vs_WT_F10.12999.12999.3 0.000843 Dec-68 R.TGQPMIHIYLDK[136.11]ETGK[136.11]PK[136.11].G "sp|Q01844|EWS_HUMAN,tr|B0QYK0|B0QYK0_HUMAN,tr|H7BY36|H7BY36_HUMAN,tr|A0A0D9SFL3|A0A0D9SFL3_HUMAN,tr|C9JGE3|C9JGE3_HUMAN" 5 2079.1249 0.62 144234 12999 3 2079.121896 694.0489 RNA-binding protein EWS OS=Homo sapiens OX=9606 GN=EWSR1 PE=1 SV=1 8.13 2496.4 - 388521 - - - -1.4434 - 2.285 0.464 - 151.5 1 2 1 -0.003 18 0 0 0 6.23E+07 1.00E+08 - - - 5.77 0.9996 221125_WJC_METTL3_EV_vs_WT_F10.13001.13001.3 1.15E-10 20/96 R.NK[136.11]EPPAPAQQLQPQPVAVQGPEPAR[166.11].V "sp|Q9HC07|TM165_HUMAN,tr|D6RBL0|D6RBL0_HUMAN,tr|D6RD79|D6RD79_HUMAN" 3 2664.4103 1.57 144236 13001 3 2664.399561 889.144 Transmembrane protein 165 OS=Homo sapiens OX=9606 GN=TMEM165 PE=1 SV=1 6.14 2496.7 - 446228 - - - -4.0185 - 3.666 0.597 - 225 1 2 1 -0.0107 25 0 0 0 5.95E+07 3.79E+07 - - - 8.1818 0.9994 221125_WJC_METTL3_EV_vs_WT_F10.13012.13012.3 0.0122 Dec-68 R.TGQPMIHIYLDKETGKPK.G "sp|Q01844|EWS_HUMAN,tr|B0QYK0|B0QYK0_HUMAN,tr|H7BY36|H7BY36_HUMAN,tr|A0A0D9SFL3|A0A0D9SFL3_HUMAN,tr|C9JGE3|C9JGE3_HUMAN" 5 2055.0823 0.62 144241 13012 3 2055.079437 686.0347 RNA-binding protein EWS OS=Homo sapiens OX=9606 GN=EWSR1 PE=1 SV=1 8.13 2498.3 - 482034 - - - -1.3917 - 2.561 0.387 - 178.9 1 2 1 -0.0029 18 0 0 0 6.23E+07 9.99E+07 - - - 5.1956 1 221125_WJC_METTL3_EV_vs_WT_F10.13015.13015.2 5.83E-08 15/24 N.SSASEPAK[136.11]EPAK[136.11]K[136.11].S "sp|Q86U44|MTA70_HUMAN,tr|F5H6D8|F5H6D8_HUMAN,tr|H0YFV6|H0YFV6_HUMAN,tr|B4DTN4|B4DTN4_HUMAN" 4 1352.7362 0.03 144242 13015 2 1352.732148 677.3754 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 8.22 2498.6 - 379073 - - - -2.9917 - 2.651 0.588 - 606.2 1 1 1 -0.004 13 0 0 0 7.00E+05 2.02E+07 - - - 5.8849 1 221125_WJC_METTL3_EV_vs_WT_F10.13021.13021.3 9.41E-11 18/92 R.QDHPSSMGVYGQESGGFSGPGENR[166.11].S "sp|Q01844|EWS_HUMAN,tr|B0QYK0|B0QYK0_HUMAN" 2 2489.0541 0.71 144245 13021 3 2489.048273 830.692 RNA-binding protein EWS OS=Homo sapiens OX=9606 GN=EWSR1 PE=1 SV=1 4.65 2499.3 - 492377 - - - -2.3551 - 3.992 0.716 - 315 1 2 0 -0.0059 24 0 0 0 8.16E+08 1.15E+09 - - - 9.7362 1 221125_WJC_METTL3_EV_vs_WT_F10.13026.13026.3 6.67E-10 18/112 R.VPSAAC[160.03]PPFPPHGAPVSASSSSSSPGGSR[166.11].G sp|Q9H7S9|ZN703_HUMAN 1 2744.2852 2.41 144248 13026 3 2744.284797 915.769 Zinc finger protein 703 OS=Homo sapiens OX=9606 GN=ZNF703 PE=1 SV=1 8.23 2499.9 - 449511 - - - -0.1458 - 3.44 0.647 - 131.4 1 2 0 -0.0004 29 0 0 0 4.23E+07 1.76E+07 - - - 8.5957 1 221125_WJC_METTL3_EV_vs_WT_F10.13033.13033.3 1.66E-14 27/92 R.QDHPSSMGVYGQESGGFSGPGENR.S "sp|Q01844|EWS_HUMAN,tr|B0QYK0|B0QYK0_HUMAN" 2 2479.0459 0.71 144251 13033 3 2479.040253 827.3559 RNA-binding protein EWS OS=Homo sapiens OX=9606 GN=EWSR1 PE=1 SV=1 4.65 2501 - 715200 - - - -2.2638 - 4.368 0.778 - 861.6 1 2 0 -0.0056 24 0 0 0 8.16E+08 1.15E+09 - - - 10.6366 0.9956 221125_WJC_METTL3_EV_vs_WT_F10.13043.13043.3 0.000371 Oct-76 R.SYNQEHSQSFTFDDAQQEDR[166.11].K "sp|Q9NPQ8|RIC8A_HUMAN,tr|E9PI04|E9PI04_HUMAN" 2 2441.0031 0.52 144257 13043 3 2441.998138 814.675 Synembryn-A OS=Homo sapiens OX=9606 GN=RIC8A PE=1 SV=3 4.1 2502.2 - 318509 - - - 407.6164 - 2.173 0.571 - 134.4 1 2 0 0.995 20 0 0 0 1.60E+06 3.08E+06 - - - 6.5133 0.9999 221125_WJC_METTL3_EV_vs_WT_F10.13054.13054.4 6.42E-05 Aug-84 K.HANIVTLHDIVHTDK[136.11].S "sp|Q00537|CDK17_HUMAN,tr|F5H6Z0|F5H6Z0_HUMAN" 2 1719.9148 1.2 144259 13054 4 1719.911499 430.986 Cyclin-dependent kinase 17 OS=Homo sapiens OX=9606 GN=CDK17 PE=1 SV=2 6.26 2503.9 - 171647 - - - -1.9007 - 1.473 0.451 - 42.6 1 2 0 -0.0033 15 0 0 0 7.27E+06 6.06E+06 - - - 3.2892 0.9993 221125_WJC_METTL3_EV_vs_WT_F10.13062.13062.4 7.48E-05 15/90 K.KLKEDISQGVHISVYR.V sp|O43395|PRPF3_HUMAN 1 1871.0265 3.57 144264 13062 4 1871.021503 468.7639 U4\U6 small nuclear ribonucleoprotein Prp3 OS=Homo sapiens OX=9606 GN=PRPF3 PE=1 SV=2 8.5 2504.9 - 415858 - - - -2.6691 - 2.585 0.444 - 229.7 1 2 1 -0.005 16 0 0 0 8.94E+06 2.50E+06 - - - 3.4237 1 221125_WJC_METTL3_EV_vs_WT_F10.13067.13067.3 1.30E-08 14/120 K.YGGSVGSQPPPVAPEPGPVPSSPSQEPPTK[136.11]R[166.11].E "sp|Q04323|UBXN1_HUMAN,tr|E9PS08|E9PS08_HUMAN,tr|A0A087WTZ5|A0A087WTZ5_HUMAN,tr|E9PJ81|E9PJ81_HUMAN,tr|E9PRQ7|E9PRQ7_HUMAN" 5 3100.5584 1.07 144266 13067 3 3100.554241 1034.5268 UBX domain-containing protein 1 OS=Homo sapiens OX=9606 GN=UBXN1 PE=1 SV=2 6.14 2505.6 - 350397 - - - -1.3572 - 2.569 0.619 - 82.9 1 2 0 -0.0042 31 0 0 0 2.84E+07 2.65E+07 - - - 7.6108 1 221125_WJC_METTL3_EV_vs_WT_F10.13069.13069.3 9.85E-09 18/120 K.YGGSVGSQPPPVAPEPGPVPSSPSQEPPTKR.E "sp|Q04323|UBXN1_HUMAN,tr|E9PS08|E9PS08_HUMAN,tr|A0A087WTZ5|A0A087WTZ5_HUMAN,tr|E9PJ81|E9PJ81_HUMAN,tr|E9PRQ7|E9PRQ7_HUMAN" 5 3082.536 1.06 144267 13069 3 3082.53664 1028.5193 UBX domain-containing protein 1 OS=Homo sapiens OX=9606 GN=UBXN1 PE=1 SV=2 6.14 2505.8 - 412850 - - - 0.2144 - 2.998 0.59 - 164.2 1 2 0 0.0007 31 0 0 0 2.67E+07 2.51E+07 - - - 7.6437 0.9904 221125_WJC_METTL3_EV_vs_WT_F10.13077.13077.4 5.63E-07 17/120 G.PK[136.11]PSTASAVPELATDPELEK[136.11]K[136.11].L "sp|Q86U44|MTA70_HUMAN,tr|B4E349|B4E349_HUMAN,tr|F5H6D8|F5H6D8_HUMAN,tr|H0YFV6|H0YFV6_HUMAN,tr|B4DTN4|B4DTN4_HUMAN" 5 2231.2111 0 144271 13077 4 2231.213091 558.8101 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 4.87 2506.7 - 512920 - - - 0.8793 - 3.075 0.428 - 185 1 1 0 0.002 21 0 0 0 4.63E+04 7.49E+07 - - - 3.3222 0.9997 221125_WJC_METTL3_EV_vs_WT_F10.13081.13081.4 2.49E-09 22/126 R.NKETLGSEAVSSNVIDYGHASK.Y sp|Q14966|ZN638_HUMAN 1 2305.1186 1.27 144273 13081 4 2305.126394 577.2869 Zinc finger protein 638 OS=Homo sapiens OX=9606 GN=ZNF638 PE=1 SV=2 5.45 2507.1 - 648410 - - - 3.3729 - 4.578 0.562 - 329.5 1 2 1 0.0078 22 0 0 0 3.31E+07 2.60E+07 - - - 4.6133 0.9354 221125_WJC_METTL3_EV_vs_WT_F10.13085.13085.3 2.45 Jul-36 R.K[136.11]QDSGHLDLR[166.11].N "sp|Q86U44|MTA70_HUMAN,tr|B4E349|B4E349_HUMAN,tr|F5H6D8|F5H6D8_HUMAN,tr|B4DTN4|B4DTN4_HUMAN" 4 1185.6221 0.02 144274 13085 3 1185.622204 396.2146 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 6.75 2507.7 - 130910 - - - 0.0835 - 1.235 0.139 - 84.7 1 2 0 0.0001 10 0 0 0 3.67E+05 1.62E+07 - - - 0.7061 1 221125_WJC_METTL3_EV_vs_WT_F10.13089.13089.3 1.87E-09 19/92 R.TQSSASLAASYAAQQHPQAAASYR.G sp|Q96PK6|RBM14_HUMAN 1 2464.1731 1.94 144275 13089 3 2464.167699 822.3983 RNA-binding protein 14 OS=Homo sapiens OX=9606 GN=RBM14 PE=1 SV=2 8.29 2508.3 - 230508 - - - -2.1975 - 3.774 0.679 - 322.5 1 2 0 -0.0054 24 0 0 0 8.13E+07 4.19E+07 - - - 9.1934 0.9996 221125_WJC_METTL3_EV_vs_WT_F10.13091.13091.4 0.00145 10/108 R.C[160.03]DLHAVNYHGDTPLHIAAR.E "sp|Q96KQ7|EHMT2_HUMAN,tr|A0A0G2JRR0|A0A0G2JRR0_HUMAN,tr|H0Y4K5|H0Y4K5_HUMAN,tr|A0A0G2JIS2|A0A0G2JIS2_HUMAN,tr|A0A0G2JRN8|A0A0G2JRN8_HUMAN,tr|A2ABF9|A2ABF9_HUMAN,tr|A0A0G2JIR1|A0A0G2JIR1_HUMAN,tr|A2ABF8|A2ABF8_HUMAN,tr|A0A0G2JK64|A0A0G2JK64_HUMAN" 9 2159.0331 0.85 144277 13091 4 2159.032739 540.7655 Histone-lysine N-methyltransferase EHMT2 OS=Homo sapiens OX=9606 GN=EHMT2 PE=1 SV=3 6.25 2508.5 - 149791 - - - -0.1468 - 1.859 0.351 - 60.2 1 2 0 -0.0003 19 0 0 0 3.77E+06 4.42E+06 - - - 2.4908 1 221125_WJC_METTL3_EV_vs_WT_F10.13094.13094.4 1.46E-10 22/162 R.IR[166.11]GPEESQPPQLYAADEEEAPGTR[166.11]DPTR[166.11].L sp|Q5RKV6|EXOS6_HUMAN 1 3138.4996 1.12 144278 13094 4 3138.492808 785.6322 Exosome complex component MTR3 OS=Homo sapiens OX=9606 GN=EXOSC6 PE=1 SV=1 4.25 2509 - 372893 - - - -2.1784 - 3.912 0.665 - 207.9 1 2 2 -0.0068 28 0 0 0 4.60E+07 4.10E+07 - - - 5.4358 0.9978 221125_WJC_METTL3_EV_vs_WT_F10.13112.13112.4 0.00789 9/108 R.WC[160.03]DKSDEDDWSKPLPPSER.L "sp|O00571|DDX3X_HUMAN,tr|A0A2R8YFR4|A0A2R8YFR4_HUMAN,tr|A0A2R8YCW1|A0A2R8YCW1_HUMAN,tr|A0A2R8YDH3|A0A2R8YDH3_HUMAN,tr|A0A2R8Y645|A0A2R8Y645_HUMAN,tr|A0A2R8YF78|A0A2R8YF78_HUMAN,tr|A0A2R8YCU0|A0A2R8YCU0_HUMAN,tr|A0A0D9SFB3|A0A0D9SFB3_HUMAN,tr|A0A2R8YFS5|A0A2R8YFS5_HUMAN,tr|A0A0D9SF53|A0A0D9SF53_HUMAN,tr|A0A2R8Y650|A0A2R8Y650_HUMAN,tr|A0A2R8Y5G6|A0A2R8Y5G6_HUMAN,tr|A0A0D9SG12|A0A0D9SG12_HUMAN,tr|F6S8Q4|F6S8Q4_HUMAN,tr|A0A2U3TZJ9|A0A2U3TZJ9_HUMAN,tr|A0A2R8Y4A4|A0A2R8Y4A4_HUMAN" 16 2346.0223 1.03 144288 13112 4 2346.026003 587.5128 ATP-dependent RNA helicase DDX3X OS=Homo sapiens OX=9606 GN=DDX3X PE=1 SV=3 4.23 2511.3 - 464088 - - - 1.5886 - 1.558 0.348 - 42.2 1 2 1 0.0037 19 0 0 0 3.41E+07 3.29E+07 - - - 2.404 1 221125_WJC_METTL3_EV_vs_WT_F10.13116.13116.4 1.76E-08 24/156 R.VLVHR[166.11]PHGPELDADPYDPGEEDPAQSR[166.11].A sp|Q9BVI4|NOC4L_HUMAN 1 3015.4226 1.11 144289 13116 4 3015.415714 754.8629 Nucleolar complex protein 4 homolog OS=Homo sapiens OX=9606 GN=NOC4L PE=1 SV=1 4.37 2511.9 - 310050 - - - -2.2726 - 3.158 0.659 - 310.7 1 2 0 -0.0069 27 0 0 0 1.45E+07 1.30E+07 - - - 5.3198 1 221125_WJC_METTL3_EV_vs_WT_F10.13118.13118.4 5.70E-10 31/162 R.IRGPEESQPPQLYAADEEEAPGTRDPTR.L sp|Q5RKV6|EXOS6_HUMAN 1 3108.4748 1.12 144290 13118 4 3108.473257 778.126 Exosome complex component MTR3 OS=Homo sapiens OX=9606 GN=EXOSC6 PE=1 SV=1 4.25 2512.1 - 1.56E+06 - - - -0.5076 - 4.329 0.642 - 517.5 1 2 2 -0.0016 28 0 0 0 4.60E+07 4.10E+07 - - - 5.2685 1 221125_WJC_METTL3_EV_vs_WT_F10.13119.13119.3 2.32E-09 23/84 R.NK[136.11]ETLGSEAVSSNVIDYGHASK[136.11].Y sp|Q14966|ZN638_HUMAN 1 2321.147 3.15 144291 13119 3 2321.148413 774.7229 Zinc finger protein 638 OS=Homo sapiens OX=9606 GN=ZNF638 PE=1 SV=2 5.45 2512.2 - 434462 - - - 0.6006 - 4.54 0.659 - 618.7 1 2 1 0.0014 22 0 0 0 2.18E+07 6.91E+06 - - - 9.4737 0.9995 221125_WJC_METTL3_EV_vs_WT_F10.13120.13120.4 1.31E-05 23/126 R.NK[136.11]ETLGSEAVSSNVIDYGHASK[136.11].Y sp|Q14966|ZN638_HUMAN 1 2321.147 1.27 144292 13120 4 2321.14111 581.294 Zinc finger protein 638 OS=Homo sapiens OX=9606 GN=ZNF638 PE=1 SV=2 5.45 2512.3 - 1.09E+06 - - - -2.5457 - 2.986 0.46 - 368.3 1 2 1 -0.0059 22 0 0 0 3.31E+07 2.60E+07 - - - 3.5861 1 221125_WJC_METTL3_EV_vs_WT_F10.13121.13121.4 3.96E-07 14/138 R.QDHPSSMGVYGQESGGFSGPGENR[166.11].S "sp|Q01844|EWS_HUMAN,tr|B0QYK0|B0QYK0_HUMAN" 2 2489.0541 0.68 144293 13121 4 2489.055492 623.2708 RNA-binding protein EWS OS=Homo sapiens OX=9606 GN=EWSR1 PE=1 SV=1 4.65 2512.4 - 392400 - - - 0.5452 - 3.033 0.596 - 152.4 1 2 0 0.0014 24 0 0 0 6.80E+06 1.00E+07 - - - 4.7693 1 221125_WJC_METTL3_EV_vs_WT_F10.13122.13122.4 1.49E-05 14/138 R.QDHPSSMGVYGQESGGFSGPGENR.S "sp|Q01844|EWS_HUMAN,tr|B0QYK0|B0QYK0_HUMAN" 2 2479.0459 0.63 144294 13122 4 2479.045004 620.7687 RNA-binding protein EWS OS=Homo sapiens OX=9606 GN=EWSR1 PE=1 SV=1 4.65 2512.6 - 318287 - - - -0.3473 - 2.611 0.575 - 135.2 1 2 0 -0.0009 24 0 0 0 6.27E+06 9.94E+06 - - - 4.5386 1 221125_WJC_METTL3_EV_vs_WT_F10.13126.13126.4 5.47E-07 18/120 R.HIDC[160.03]AHVYQNENEVGVAIQEK.L "sp|P15121|ALDR_HUMAN,tr|E9PCX2|E9PCX2_HUMAN,tr|E9PEF9|E9PEF9_HUMAN" 3 2452.1441 0.24 144296 13126 4 2452.148466 614.0433 Aldo-keto reductase family 1 member B1 OS=Homo sapiens OX=9606 GN=AKR1B1 PE=1 SV=3 4.8 2513 - 333584 - - - 1.7715 - 3.424 0.599 - 275.1 1 2 0 0.0043 21 0 0 0 4.68E+06 1.98E+07 - - - 4.8454 0.9996 221125_WJC_METTL3_EV_vs_WT_F10.13127.13127.4 0.000309 13/156 K.ASETPPPVAQPK[136.11]PEAPHPGLETTLQER[166.11].L sp|Q6P1N0|C2D1A_HUMAN 1 2894.4893 0.67 144297 13127 4 2894.487266 724.6296 Coiled-coil and C2 domain-containing protein 1A OS=Homo sapiens OX=9606 GN=CC2D1A PE=1 SV=1 4.91 2513.1 - 319198 - - - -0.7048 - 2.049 0.348 - 82.9 1 2 0 -0.002 27 0 0 0 5.32E+06 7.95E+06 - - - 2.4789 1 221125_WJC_METTL3_EV_vs_WT_F10.13128.13128.4 2.38E-11 21/138 R.TQSSASLAASYAAQQHPQAAASYR.G sp|Q96PK6|RBM14_HUMAN 1 2464.1731 2.68 144298 13128 4 2464.172023 617.0506 RNA-binding protein 14 OS=Homo sapiens OX=9606 GN=RBM14 PE=1 SV=2 8.29 2513.3 - 854528 - - - -0.4427 - 4.304 0.592 - 200.3 1 2 0 -0.0011 24 0 0 0 2.17E+07 8.10E+06 - - - 4.8469 1 221125_WJC_METTL3_EV_vs_WT_F10.13129.13129.4 3.62E-10 21/156 R.VLVHRPHGPELDADPYDPGEEDPAQSR.A sp|Q9BVI4|NOC4L_HUMAN 1 2995.406 1.11 144299 13129 4 2995.408082 749.8588 Nucleolar complex protein 4 homolog OS=Homo sapiens OX=9606 GN=NOC4L PE=1 SV=1 4.37 2513.4 - 469812 - - - 0.6861 - 3.423 0.65 - 213.9 1 2 0 0.0021 27 0 0 0 1.45E+07 1.30E+07 - - - 5.268 0.9995 221125_WJC_METTL3_EV_vs_WT_F10.13130.13130.4 7.77E-05 13/102 K.AQQNNVEHK[136.11]VETFSGVYK[136.11].K "sp|P62081|RS7_HUMAN,tr|A0A2R8Y623|A0A2R8Y623_HUMAN" 2 2093.0513 0.81 144300 13130 4 2093.051756 524.2701 40S ribosomal protein S7 OS=Homo sapiens OX=9606 GN=RPS7 PE=1 SV=1 6.8 2513.5 - 465744 - - - 0.2332 - 2.674 0.399 - 137.8 1 2 1 0.0005 18 0 0 0 1.39E+08 1.71E+08 - - - 3.0357 1 221125_WJC_METTL3_EV_vs_WT_F10.13132.13132.3 1.16E-10 17/92 K.LSLDVEQAPSGQHSQAQLSGQQQR[166.11].L "sp|O00411|RPOM_HUMAN,tr|K7EMH3|K7EMH3_HUMAN" 2 2601.2771 0.8 144302 13132 3 2601.2808 868.0996 "DNA-directed RNA polymerase, mitochondrial OS=Homo sapiens OX=9606 GN=POLRMT PE=1 SV=2" 5.32 2513.8 - 267814 - - - 1.432 - 3.486 0.587 - 185.1 1 2 0 0.0037 24 0 0 0 6.69E+06 8.41E+06 - - - 7.9838 1 221125_WJC_METTL3_EV_vs_WT_F10.13133.13133.4 0.000289 11/180 K.KVASGVLSPPPAAPPPSSSSVPEAGGPPIKK.Q "sp|Q8IXM2|BAP18_HUMAN,tr|H0YIS7|H0YIS7_HUMAN,tr|F8W038|F8W038_HUMAN,tr|F8W1H0|F8W1H0_HUMAN" 4 2905.5913 1.78 144303 13133 4 2905.593809 727.4051 Chromatin complexes subunit BAP18 OS=Homo sapiens OX=9606 GN=BAP18 PE=1 SV=1 9.7 2513.9 - 242299 - - - 0.8604 - 2.092 0.504 - 21.4 1 2 0 0.0025 31 0 0 0 1.13E+07 6.34E+06 - - - 3.8365 0.9999 221125_WJC_METTL3_EV_vs_WT_F10.13138.13138.3 2.00E-09 17/68 K.AQQNNVEHK[136.11]VETFSGVYK[136.11].K "sp|P62081|RS7_HUMAN,tr|A0A2R8Y623|A0A2R8Y623_HUMAN" 2 2093.0513 0.79 144307 13138 3 2093.048163 698.691 40S ribosomal protein S7 OS=Homo sapiens OX=9606 GN=RPS7 PE=1 SV=1 6.8 2514.5 - 968040 - - - -1.4835 - 3.223 0.568 - 320.3 1 2 1 -0.0031 18 0 0 0 1.10E+08 1.40E+08 - - - 7.786 0.9996 221125_WJC_METTL3_EV_vs_WT_F10.13142.13142.4 0.00555 14/102 K.AQQNNVEHKVETFSGVYK.K "sp|P62081|RS7_HUMAN,tr|A0A2R8Y623|A0A2R8Y623_HUMAN" 2 2077.0229 0.81 144309 13142 4 2077.025877 520.263 40S ribosomal protein S7 OS=Homo sapiens OX=9606 GN=RPS7 PE=1 SV=1 6.8 2515 - 1.40E+06 - - - 1.4487 - 2.91 0.427 - 157.4 1 2 1 0.003 18 0 0 0 1.39E+08 1.71E+08 - - - 3.3077 0.9999 221125_WJC_METTL3_EV_vs_WT_F10.13143.13143.3 7.16E-07 15/68 K.AQQNNVEHKVETFSGVYK.K "sp|P62081|RS7_HUMAN,tr|A0A2R8Y623|A0A2R8Y623_HUMAN" 2 2077.0229 0.79 144310 13143 3 2077.025409 693.3482 40S ribosomal protein S7 OS=Homo sapiens OX=9606 GN=RPS7 PE=1 SV=1 6.8 2515.2 - 773995 - - - 1.2234 - 3.51 0.57 - 231 1 2 1 0.0025 18 0 0 0 1.10E+08 1.40E+08 - - - 8.0208 1 221125_WJC_METTL3_EV_vs_WT_F10.13148.13148.4 3.32E-11 23/138 R.TQSSASLAASYAAQQHPQAAASYR[166.11].G sp|Q96PK6|RBM14_HUMAN 1 2474.1814 2.69 144313 13148 4 2474.180325 619.5526 RNA-binding protein 14 OS=Homo sapiens OX=9606 GN=RBM14 PE=1 SV=2 8.29 2515.9 - 701181 - - - -0.428 - 4.194 0.554 - 289.4 1 2 0 -0.0011 24 0 0 0 2.17E+07 8.08E+06 - - - 4.5079 0.9999 221125_WJC_METTL3_EV_vs_WT_F10.13149.13149.3 0.000342 Dec-44 R.QSVEADINGLRR.V "sp|P13645|K1C10_HUMAN,sp|Q7Z3Y8|K1C27_HUMAN,sp|P13646|K1C13_HUMAN,tr|A0A1B0GVI3|A0A1B0GVI3_HUMAN,tr|K7EMD9|K7EMD9_HUMAN,tr|K7ERE3|K7ERE3_HUMAN" 6 1356.711 272.66 144314 13149 3 1356.711365 453.2443 "Keratin, type I cytoskeletal 10 OS=Homo sapiens OX=9606 GN=KRT10 PE=1 SV=6" 6.07 2516 - 528126 - - - 0.2867 - 2.107 0.389 - 241.9 1 2 0 0.0004 12 0 0 0 2.78E+07 1.02E+05 - - - 4.9426 0.9999 221125_WJC_METTL3_EV_vs_WT_F10.13151.13151.4 1.02E-05 14/168 R.VPSAAC[160.03]PPFPPHGAPVSASSSSSSPGGSR.G sp|Q9H7S9|ZN703_HUMAN 1 2734.2769 3.81 144316 13151 4 2734.268556 684.5765 Zinc finger protein 703 OS=Homo sapiens OX=9606 GN=ZNF703 PE=1 SV=1 8.23 2516.2 - 223066 - - - -3.0615 - 2.419 0.493 - 95.8 1 2 0 -0.0084 29 0 0 0 4.63E+06 1.22E+06 - - - 3.787 0.9999 221125_WJC_METTL3_EV_vs_WT_F10.13156.13156.4 2.62E-08 17/108 R.WC[160.03]DK[136.11]SDEDDWSK[136.11]PLPPSER[166.11].L "sp|O00571|DDX3X_HUMAN,tr|A0A2R8YFR4|A0A2R8YFR4_HUMAN,tr|A0A2R8YCW1|A0A2R8YCW1_HUMAN,tr|A0A2R8YDH3|A0A2R8YDH3_HUMAN,tr|A0A2R8Y645|A0A2R8Y645_HUMAN,tr|A0A2R8YF78|A0A2R8YF78_HUMAN,tr|A0A2R8YCU0|A0A2R8YCU0_HUMAN,tr|A0A0D9SFB3|A0A0D9SFB3_HUMAN,tr|A0A2R8YFS5|A0A2R8YFS5_HUMAN,tr|A0A0D9SF53|A0A0D9SF53_HUMAN,tr|A0A2R8Y650|A0A2R8Y650_HUMAN,tr|A0A2R8Y5G6|A0A2R8Y5G6_HUMAN,tr|A0A0D9SG12|A0A0D9SG12_HUMAN,tr|F6S8Q4|F6S8Q4_HUMAN,tr|A0A2U3TZJ9|A0A2U3TZJ9_HUMAN,tr|A0A2R8Y4A4|A0A2R8Y4A4_HUMAN" 16 2372.0589 1.03 144319 13156 4 2372.058588 594.022 ATP-dependent RNA helicase DDX3X OS=Homo sapiens OX=9606 GN=DDX3X PE=1 SV=3 4.23 2516.9 - 778852 - - - -0.1509 - 2.468 0.622 - 187.7 1 2 1 -0.0004 19 0 0 0 3.38E+07 3.27E+07 - - - 4.9454 0.9999 221125_WJC_METTL3_EV_vs_WT_F10.13159.13159.4 2.16E-05 13/96 R.EIAGHIMEFSQDQHGSR[166.11].F "sp|Q14671|PUM1_HUMAN,tr|Q5T1Z8|Q5T1Z8_HUMAN,tr|H0YDK8|H0YDK8_HUMAN,tr|H0YEH2|H0YEH2_HUMAN,tr|Q5T1Z4|Q5T1Z4_HUMAN,tr|E9PR38|E9PR38_HUMAN" 6 1950.8882 2.44 144322 13159 4 1950.884785 488.7293 Pumilio homolog 1 OS=Homo sapiens OX=9606 GN=PUM1 PE=1 SV=3 5.28 2517.3 - 262041 - - - -1.7397 - 2.504 0.48 - 119.8 1 2 0 -0.0034 17 0 0 0 2.35E+07 9.62E+06 - - - 3.7217 1 221125_WJC_METTL3_EV_vs_WT_F10.13165.13165.4 4.42E-05 19/96 R.EIAGHIMEFSQDQHGSR.F "sp|Q14671|PUM1_HUMAN,tr|Q5T1Z8|Q5T1Z8_HUMAN,tr|H0YDK8|H0YDK8_HUMAN,tr|H0YEH2|H0YEH2_HUMAN,tr|Q5T1Z4|Q5T1Z4_HUMAN,tr|E9PR38|E9PR38_HUMAN" 6 1940.8799 2.42 144326 13165 4 1940.880746 486.2273 Pumilio homolog 1 OS=Homo sapiens OX=9606 GN=PUM1 PE=1 SV=3 5.28 2518 - 787907 - - - 0.4312 - 3.389 0.589 - 288.9 1 2 0 0.0008 17 0 0 0 2.53E+07 1.05E+07 - - - 4.7762 0.9932 221125_WJC_METTL3_EV_vs_WT_F10.13171.13171.3 5.08E-08 17/80 G.PK[136.11]PSTASAVPELATDPELEK[136.11]K[136.11].L "sp|Q86U44|MTA70_HUMAN,tr|B4E349|B4E349_HUMAN,tr|F5H6D8|F5H6D8_HUMAN,tr|H0YFV6|H0YFV6_HUMAN,tr|B4DTN4|B4DTN4_HUMAN" 5 2231.2111 0.001 144330 13171 3 2231.203492 744.7443 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 4.87 2518.8 - 594535 - - - -3.4228 - 3.278 0.575 - 244.8 1 1 0 -0.0076 21 0 0 0 0.00E+00 1.46E+07 - - - 7.7949 0.9999 221125_WJC_METTL3_EV_vs_WT_F10.13178.13178.4 1.22E-07 21/180 K.K[136.11]VASGVLSPPPAAPPPSSSSVPEAGGPPIK[136.11]K[136.11].Q "sp|Q8IXM2|BAP18_HUMAN,tr|H0YIS7|H0YIS7_HUMAN,tr|F8W038|F8W038_HUMAN,tr|F8W1H0|F8W1H0_HUMAN" 4 2929.6339 1.89 144334 13178 4 2929.632644 733.4158 Chromatin complexes subunit BAP18 OS=Homo sapiens OX=9606 GN=BAP18 PE=1 SV=1 9.7 2519.7 - 300781 - - - -0.4318 - 3.448 0.461 - 169.2 1 2 0 -0.0013 31 0 0 0 1.39E+07 7.35E+06 - - - 3.6144 0.9999 221125_WJC_METTL3_EV_vs_WT_F10.13184.13184.4 2.00E-07 16/90 K.R[166.11]K[136.11]DLANLEVPHELPTK[136.11].Q "sp|Q8WXI9|P66B_HUMAN,tr|A0A0U1RR34|A0A0U1RR34_HUMAN,tr|A0A0U1RRM1|A0A0U1RRM1_HUMAN,tr|A0A0U1RRK3|A0A0U1RRK3_HUMAN" 4 1885.0632 1.76 144338 13184 4 1885.062686 472.2731 Transcriptional repressor p66-beta OS=Homo sapiens OX=9606 GN=GATAD2B PE=1 SV=1 6.76 2520.4 - 323823 - - - -0.2552 - 3.071 0.49 - 174.3 1 2 1 -0.0005 16 0 0 0 1.24E+07 7.06E+06 - - - 3.8861 0.8866 221125_WJC_METTL3_EV_vs_WT_F10.13185.13185.3 1.02 May-76 K.YDLSGR[166.11]PLNIK[136.11]EDPDGENAR[166.11].R "sp|Q9P2K5|MYEF2_HUMAN,tr|A0A0A0MR39|A0A0A0MR39_HUMAN,tr|A0A087WUT0|A0A087WUT0_HUMAN,tr|A0A0A0MQW0|A0A0A0MQW0_HUMAN" 4 2286.1235 0.43 144339 13185 3 2286.125579 763.0484 Myelin expression factor 2 OS=Homo sapiens OX=9606 GN=MYEF2 PE=1 SV=3 4.44 2520.6 - 218570 - - - 0.919 - 1.295 0.212 - 19.7 4 2 1 0.0021 20 0 0 0 3.71E+06 8.73E+06 - - - 1.2515 0.9999 221125_WJC_METTL3_EV_vs_WT_F10.13193.13193.4 0.000175 Nov-96 K.KEENDDDFTFGQSALKK.L sp|Q8N5C6|SRBD1_HUMAN 1 1970.9222 0.64 144345 13193 4 1970.917468 493.7378 S1 RNA-binding domain-containing protein 1 OS=Homo sapiens OX=9606 GN=SRBD1 PE=1 SV=2 4.44 2521.7 - 213906 - - - -2.376 - 2.051 0.487 - 95.7 1 2 0 -0.0047 17 0 0 0 2.08E+06 3.28E+06 - - - 3.713 1 221125_WJC_METTL3_EV_vs_WT_F10.13197.13197.3 4.09E-11 21/64 R.EIAGHIMEFSQDQHGSR[166.11].F "sp|Q14671|PUM1_HUMAN,tr|Q5T1Z8|Q5T1Z8_HUMAN,tr|H0YDK8|H0YDK8_HUMAN,tr|H0YEH2|H0YEH2_HUMAN,tr|Q5T1Z4|Q5T1Z4_HUMAN,tr|E9PR38|E9PR38_HUMAN" 6 1950.8882 1.88 144347 13197 3 1950.886479 651.3033 Pumilio homolog 1 OS=Homo sapiens OX=9606 GN=PUM1 PE=1 SV=3 5.28 2522.1 - 565234 - - - -0.8714 - 3.607 0.636 - 582.2 1 2 0 -0.0017 17 0 0 0 2.35E+07 1.25E+07 - - - 8.8712 1 221125_WJC_METTL3_EV_vs_WT_F10.13204.13204.4 3.47E-08 17/138 R.QVQHEESTEGEADHSGYAGELGFR.A "sp|Q92890|UFD1_HUMAN,tr|C9JNP9|C9JNP9_HUMAN" 2 2632.1426 1.35 144352 13204 4 2632.144138 659.0429 Ubiquitin recognition factor in ER-associated degradation protein 1 OS=Homo sapiens OX=9606 GN=UFD1 PE=1 SV=3 4.41 2523 - 529420 - - - 0.5836 - 3.482 0.626 - 238.5 1 2 0 0.0015 24 0 0 0 6.11E+06 4.52E+06 - - - 5.0747 0.9973 221125_WJC_METTL3_EV_vs_WT_F10.13205.13205.4 5.11E-07 20/126 G.GPK[136.11]PSTASAVPELATDPELEK[136.11]K[136.11].L "sp|Q86U44|MTA70_HUMAN,tr|B4E349|B4E349_HUMAN,tr|F5H6D8|F5H6D8_HUMAN,tr|H0YFV6|H0YFV6_HUMAN,tr|B4DTN4|B4DTN4_HUMAN" 5 2288.2326 0.04 144353 13205 4 2288.232171 573.0654 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 4.87 2523 - 1.45E+06 - - - -0.1844 - 3.453 0.536 - 221.3 1 1 0 -0.0004 22 0 0 0 1.45E+06 3.48E+07 - - - 4.2967 0.9998 221125_WJC_METTL3_EV_vs_WT_F10.13210.13210.4 0.00477 16/96 K.DHPALNYNIVSGPPSHK.T "sp|O15269|SPTC1_HUMAN,tr|A0A2R8Y6A2|A0A2R8Y6A2_HUMAN,tr|A0A2R8Y4S0|A0A2R8Y4S0_HUMAN" 3 1844.9169 1.5 144358 13210 4 1844.918944 462.2365 Serine palmitoyltransferase 1 OS=Homo sapiens OX=9606 GN=SPTLC1 PE=1 SV=1 6.92 2523.7 - 220825 - - - 1.083 - 2.683 0.389 - 202.1 1 2 0 0.002 17 0 0 0 8.16E+06 5.44E+06 - - - 2.954 1 221125_WJC_METTL3_EV_vs_WT_F10.13211.13211.3 4.17E-08 Sep-64 K.K[136.11]EENDDDFTFGQSALK[136.11]K[136.11].L sp|Q8N5C6|SRBD1_HUMAN 1 1994.9648 0.84 144359 13211 3 1994.9656 665.9955 S1 RNA-binding domain-containing protein 1 OS=Homo sapiens OX=9606 GN=SRBD1 PE=1 SV=2 4.44 2523.8 - 216179 - - - 0.4256 - 2.16 0.546 - 107.7 1 2 0 0.0008 17 0 0 0 1.59E+06 1.90E+06 - - - 6.5726 0.9998 221125_WJC_METTL3_EV_vs_WT_F10.13215.13215.4 1.24E-07 20/114 K.YDLSGRPLNIKEDPDGENAR.R "sp|Q9P2K5|MYEF2_HUMAN,tr|A0A0A0MR39|A0A0A0MR39_HUMAN,tr|A0A087WUT0|A0A087WUT0_HUMAN,tr|A0A0A0MQW0|A0A0A0MQW0_HUMAN" 4 2258.0927 0.15 144361 13215 4 2258.098514 565.5305 Myelin expression factor 2 OS=Homo sapiens OX=9606 GN=MYEF2 PE=1 SV=3 4.44 2524.4 - 560038 - - - 2.5579 - 3.307 0.551 - 212.6 1 2 1 0.0058 20 0 0 0 8.96E+06 5.94E+07 - - - 4.4202 0.9986 221125_WJC_METTL3_EV_vs_WT_F10.13217.13217.3 0.0285 Sep-52 R.TYSLGSALR[166.11]PSTSR[166.11].S "sp|P08670|VIME_HUMAN,tr|B0YJC4|B0YJC4_HUMAN,tr|A0A1B0GVG8|A0A1B0GVG8_HUMAN,tr|A0A1B0GTT5|A0A1B0GTT5_HUMAN" 4 1514.7956 1.93 144363 13217 3 1514.79921 505.9391 Vimentin OS=Homo sapiens OX=9606 GN=VIM PE=1 SV=4 10.83 2524.6 - 350245 - - - 2.3858 - 1.347 0.395 - 82.3 1 2 0 0.0036 14 0 0 0 1.34E+07 6.94E+06 - - - 3.7345 0.9954 221125_WJC_METTL3_EV_vs_WT_F10.13219.13219.3 7.07E-07 13/84 G.GPK[136.11]PSTASAVPELATDPELEK[136.11]K[136.11].L "sp|Q86U44|MTA70_HUMAN,tr|B4E349|B4E349_HUMAN,tr|F5H6D8|F5H6D8_HUMAN,tr|H0YFV6|H0YFV6_HUMAN,tr|B4DTN4|B4DTN4_HUMAN" 5 2288.2326 0.001 144365 13219 3 2288.237688 763.7515 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 4.87 2524.9 - 234787 - - - 2.2266 - 2.938 0.539 - 159.7 1 1 0 0.0051 22 0 0 0 0.00E+00 6.76E+06 - - - 7.103 0.9994 221125_WJC_METTL3_EV_vs_WT_F10.13220.13220.4 4.39E-05 Sep-84 K.GVIVDK[136.11]DFSHPQMPK[136.11].K "sp|P48643|TCPE_HUMAN,tr|E9PCA1|E9PCA1_HUMAN,tr|B7ZAR1|B7ZAR1_HUMAN,tr|E7ENZ3|E7ENZ3_HUMAN" 4 1712.8891 0.74 144366 13220 4 1712.89491 429.2295 T-complex protein 1 subunit epsilon OS=Homo sapiens OX=9606 GN=CCT5 PE=1 SV=1 6.75 2525 - 183851 - - - 3.4054 - 1.997 0.512 - 30.9 1 2 1 0.0058 15 0 0 0 5.05E+06 6.82E+06 - - - 3.9283 1 221125_WJC_METTL3_EV_vs_WT_F10.13223.13223.3 1.12E-15 30/112 R.VPSAAC[160.03]PPFPPHGAPVSASSSSSSPGGSR.G sp|Q9H7S9|ZN703_HUMAN 1 2734.2769 2.24 144368 13223 3 2734.278613 912.4329 Zinc finger protein 703 OS=Homo sapiens OX=9606 GN=ZNF703 PE=1 SV=1 8.23 2525.5 - 567529 - - - 0.6166 - 5.125 0.74 - 642.9 1 2 0 0.0017 29 0 0 0 2.24E+07 1.00E+07 - - - 10.5493 1 221125_WJC_METTL3_EV_vs_WT_F10.13231.13231.3 0.000393 17/64 R.EIAGHIMEFSQDQHGSR.F "sp|Q14671|PUM1_HUMAN,tr|Q5T1Z8|Q5T1Z8_HUMAN,tr|H0YDK8|H0YDK8_HUMAN,tr|H0YEH2|H0YEH2_HUMAN,tr|Q5T1Z4|Q5T1Z4_HUMAN,tr|E9PR38|E9PR38_HUMAN" 6 1940.8799 1.82 144373 13231 3 1940.884848 647.9672 Pumilio homolog 1 OS=Homo sapiens OX=9606 GN=PUM1 PE=1 SV=3 5.28 2526.6 - 319827 - - - 2.5447 - 3.261 0.563 - 358.4 1 2 0 0.0049 17 0 0 0 2.40E+07 1.32E+07 - - - 7.8017 0.9125 221125_WJC_METTL3_EV_vs_WT_F10.13232.13232.4 0.00181 9/102 G.LLQDDAHPTLVTYADHSK[136.11].L "sp|Q86U44|MTA70_HUMAN,tr|F5H6D8|F5H6D8_HUMAN,tr|H0YFV6|H0YFV6_HUMAN,tr|B4DTN4|B4DTN4_HUMAN" 4 2031.0153 0.15 144374 13232 4 2031.022404 508.7611 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 5.13 2526.7 - 269656 - - - 3.5125 - 1.678 0.399 - 65.3 1 1 0 0.0071 18 0 0 0 1.43E+06 9.28E+06 - - - 2.8742 1 221125_WJC_METTL3_EV_vs_WT_F10.13238.13238.3 4.04E-13 17/64 K.DHPALNYNIVSGPPSHK[136.11].T "sp|O15269|SPTC1_HUMAN,tr|A0A2R8Y6A2|A0A2R8Y6A2_HUMAN,tr|A0A2R8Y4S0|A0A2R8Y4S0_HUMAN" 3 1852.9311 0.63 144378 13238 3 1852.936363 618.651 Serine palmitoyltransferase 1 OS=Homo sapiens OX=9606 GN=SPTLC1 PE=1 SV=1 6.92 2527.5 - 231220 - - - 2.8155 - 3.624 0.67 - 444.9 1 2 0 0.0052 17 0 0 0 2.97E+06 4.70E+06 - - - 9.2612 0.9999 221125_WJC_METTL3_EV_vs_WT_F10.13243.13243.3 3.54E-09 15/76 K.R[166.11]GLLQDDAHPTLVTYADHSK[136.11].L "sp|Q86U44|MTA70_HUMAN,tr|F5H6D8|F5H6D8_HUMAN,tr|H0YFV6|H0YFV6_HUMAN,tr|B4DTN4|B4DTN4_HUMAN" 4 2254.1461 0 144383 13243 3 2254.152672 752.3893 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 5.99 2528.1 - 161265 - - - 2.9089 - 3.17 0.563 - 292.5 1 2 0 0.0066 20 0 0 0 4.51E+04 9.55E+06 - - - 7.6141 1 221125_WJC_METTL3_EV_vs_WT_F10.13248.13248.3 5.02E-12 17/60 K.KQISNLQQSISDAEQR.G sp|P04264|K2C1_HUMAN 1 1843.9388 1510.32 144386 13248 3 1843.945076 615.6535 "Keratin, type II cytoskeletal 1 OS=Homo sapiens OX=9606 GN=KRT1 PE=1 SV=6" 6.07 2528.8 - 1.28E+06 - - - 3.4014 - 3.297 0.606 - 349.7 1 2 0 0.0063 16 0 0 0 1.10E+08 7.26E+04 - - - 8.3557 0.9999 221125_WJC_METTL3_EV_vs_WT_F10.13250.13250.4 2.88E-08 18/96 K.DHPALNYNIVSGPPSHK[136.11].T "sp|O15269|SPTC1_HUMAN,tr|A0A2R8Y6A2|A0A2R8Y6A2_HUMAN,tr|A0A2R8Y4S0|A0A2R8Y4S0_HUMAN" 3 1852.9311 1.94 144388 13250 4 1852.937712 464.2401 Serine palmitoyltransferase 1 OS=Homo sapiens OX=9606 GN=SPTLC1 PE=1 SV=1 6.92 2529.1 - 339398 - - - 3.5436 - 2.862 0.614 - 274 1 2 0 0.0066 17 0 0 0 1.15E+07 5.96E+06 - - - 4.9335 0.9991 221125_WJC_METTL3_EV_vs_WT_F10.13251.13251.3 0.00135 Sep-76 R.QSDENNLKDPGGSEFDSISK.N "sp|Q9H6K1|ILRUN_HUMAN,tr|Q5TH58|Q5TH58_HUMAN" 2 2165.9713 0.97 144389 13251 3 2165.976428 722.9977 Protein ILRUN OS=Homo sapiens OX=9606 GN=ILRUN PE=1 SV=2 4.11 2529.2 - 204557 - - - 2.374 - 2.128 0.449 - 100.2 1 2 1 0.0051 20 0 0 0 2.38E+06 2.45E+06 - - - 5.3766 1 221125_WJC_METTL3_EV_vs_WT_F10.13256.13256.3 1.84E-10 15/84 R.LLEGEDAHLSSSQFSSGSQSSR.D sp|P02533|K1C14_HUMAN 1 2308.0567 999 144392 13256 3 2308.064789 770.3595 "Keratin, type I cytoskeletal 14 OS=Homo sapiens OX=9606 GN=KRT14 PE=1 SV=4" 4.65 2529.8 - 481734 - - - 3.4843 - 3.266 0.716 - 150.3 1 2 0 0.008 22 0 0 0 6.13E+07 0.00E+00 - - - 9.3265 1 221125_WJC_METTL3_EV_vs_WT_F10.13257.13257.3 6.99E-10 20/68 R.HYNEEGSQVYNDAHILEK[136.11].L "sp|Q86U86|PB1_HUMAN,tr|H0Y5B5|H0Y5B5_HUMAN,tr|E7EVG2|E7EVG2_HUMAN" 3 2152.9905 1.69 144393 13257 3 2153.000364 718.6708 Protein polybromo-1 OS=Homo sapiens OX=9606 GN=PBRM1 PE=1 SV=1 4.8 2530 - 355849 - - - 4.576 - 4.31 0.708 - 785.5 1 2 0 0.0099 18 0 0 0 2.88E+07 1.70E+07 - - - 10.0687 0.9955 221125_WJC_METTL3_EV_vs_WT_F10.13264.13264.3 5.19E-06 17/52 S.AVPELATDPELEK[136.11]K[136.11].L "sp|Q86U44|MTA70_HUMAN,tr|B4E349|B4E349_HUMAN,tr|F5H6D8|F5H6D8_HUMAN,tr|H0YFV6|H0YFV6_HUMAN,tr|B4DTN4|B4DTN4_HUMAN" 5 1554.8476 0 144398 13264 3 1554.850972 519.2898 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 4.41 2530.9 - 1.40E+06 - - - 2.1758 - 2.832 0.518 - 387.5 1 1 0 0.0034 14 0 0 0 2.16E+04 2.66E+07 - - - 7.0807 0.9999 221125_WJC_METTL3_EV_vs_WT_F10.13265.13265.4 7.86E-08 19/120 R.KGSLESPATDVFGSTEEGEKR.W sp|O00232|PSD12_HUMAN 1 2223.0655 0.82 144399 13265 4 2223.074773 556.7737 26S proteasome non-ATPase regulatory subunit 12 OS=Homo sapiens OX=9606 GN=PSMD12 PE=1 SV=3 4.59 2531.1 - 457716 - - - 4.1618 - 3.704 0.564 - 211.5 1 2 0 0.0093 21 0 0 0 6.19E+07 7.52E+07 - - - 4.5654 0.9997 221125_WJC_METTL3_EV_vs_WT_F10.13272.13272.4 5.86E-05 13/144 K.VPEPC[160.03]HPKVPEPC[160.03]PSIVTPAPAQQK.T sp|P22528|SPR1B_HUMAN 1 2762.3884 9.85 144404 13272 4 2762.395167 691.6044 Cornifin-B OS=Homo sapiens OX=9606 GN=SPRR1B PE=1 SV=2 6.71 2532 - 193721 - - - 2.4526 - 2.901 0.5 - 83.5 1 2 1 0.0068 25 0 0 0 7.98E+06 8.10E+05 - - - 3.9149 0.9999 221125_WJC_METTL3_EV_vs_WT_F10.13273.13273.4 0.000505 Oct-96 R.DSAYQSITHYR[166.11]PVSASR[166.11].S "sp|P50402|EMD_HUMAN,tr|A0A804HIV7|A0A804HIV7_HUMAN,tr|Q5HY57|Q5HY57_HUMAN" 3 1956.9557 1.36 144405 13273 4 1956.956576 490.2462 Emerin OS=Homo sapiens OX=9606 GN=EMD PE=1 SV=1 8.6 2532.1 - 114472 - - - 0.4589 - 1.575 0.47 - 50.9 1 2 0 0.0009 17 0 0 0 6.69E+07 4.92E+07 - - - 3.4743 1 221125_WJC_METTL3_EV_vs_WT_F10.13275.13275.3 3.39E-12 21/112 R.VPSAAC[160.03]PPFPPHGAPVSASSSSSSPGGSR[166.11].G sp|Q9H7S9|ZN703_HUMAN 1 2744.2852 2.12 144407 13275 3 2744.292671 915.769 Zinc finger protein 703 OS=Homo sapiens OX=9606 GN=ZNF703 PE=1 SV=1 8.23 2532.4 - 292562 - - - 2.7235 - 3.155 0.697 - 237.8 1 2 0 0.0075 29 0 0 0 3.50E+07 1.65E+07 - - - 8.9522 1 221125_WJC_METTL3_EV_vs_WT_F10.13276.13276.4 1.52E-08 17/102 R.HYNEEGSQVYNDAHILEK.L "sp|Q86U86|PB1_HUMAN,tr|H0Y5B5|H0Y5B5_HUMAN,tr|E7EVG2|E7EVG2_HUMAN" 3 2144.9763 1.4 144408 13276 4 2144.981923 537.2514 Protein polybromo-1 OS=Homo sapiens OX=9606 GN=PBRM1 PE=1 SV=1 4.8 2532.5 - 280619 - - - 2.6159 - 3.232 0.636 - 241.9 1 2 0 0.0056 18 0 0 0 5.09E+06 3.65E+06 - - - 5.162 0.9987 221125_WJC_METTL3_EV_vs_WT_F10.13278.13278.3 9.70E-06 Oct-52 R.NALQQENHIIDGVK.V "sp|Q9GZT3|SLIRP_HUMAN,tr|H0YJW7|H0YJW7_HUMAN,tr|A0A087WUN7|A0A087WUN7_HUMAN,tr|G3V2S9|G3V2S9_HUMAN,tr|H0YJ40|H0YJ40_HUMAN,tr|G3V4X6|G3V4X6_HUMAN" 6 1577.8162 1.38 144410 13278 3 1577.82306 526.946 "SRA stem-loop-interacting RNA-binding protein, mitochondrial OS=Homo sapiens OX=9606 GN=SLIRP PE=1 SV=1" 5.32 2532.8 - 120312 - - - 4.3674 - 2.018 0.411 - 136.3 1 2 0 0.0069 14 0 0 0 3.57E+06 2.58E+06 - - - 4.9862 1 221125_WJC_METTL3_EV_vs_WT_F10.13282.13282.4 2.09E-11 18/102 R.HYNEEGSQVYNDAHILEK[136.11].L "sp|Q86U86|PB1_HUMAN,tr|H0Y5B5|H0Y5B5_HUMAN,tr|E7EVG2|E7EVG2_HUMAN" 3 2152.9905 1.43 144412 13282 4 2152.997352 539.2549 Protein polybromo-1 OS=Homo sapiens OX=9606 GN=PBRM1 PE=1 SV=1 4.8 2533.2 - 263243 - - - 3.177 - 3.542 0.669 - 329.8 1 2 0 0.0068 18 0 0 0 5.55E+06 3.88E+06 - - - 5.4803 0.9837 221125_WJC_METTL3_EV_vs_WT_F10.13283.13283.4 0.00539 13/96 R.DSAYQSITHYRPVSASR.S "sp|P50402|EMD_HUMAN,tr|A0A804HIV7|A0A804HIV7_HUMAN,tr|Q5HY57|Q5HY57_HUMAN" 3 1936.9391 1.36 144413 13283 4 1936.946191 485.2421 Emerin OS=Homo sapiens OX=9606 GN=EMD PE=1 SV=1 8.6 2533.4 - 306876 - - - 3.6413 - 2.101 0.24 - 118.1 1 2 0 0.0071 17 0 0 0 6.68E+07 4.92E+07 - - - 1.5708 1 221125_WJC_METTL3_EV_vs_WT_F10.13284.13284.4 4.27E-09 19/102 R.HWGAGWDGGHHYPEMDAR[166.11].Q sp|Q00587|BORG5_HUMAN 1 2087.8684 1.53 144414 13284 4 2087.874039 522.9744 Cdc42 effector protein 1 OS=Homo sapiens OX=9606 GN=CDC42EP1 PE=1 SV=1 5.73 2533.5 - 272598 - - - 2.6788 - 2.561 0.613 - 235.7 1 2 0 0.0056 18 0 0 0 2.89E+06 1.89E+06 - - - 4.8821 0.982 221125_WJC_METTL3_EV_vs_WT_F10.13285.13285.3 0.00236 Sep-48 K.SVEEGKIDGIIDK.T sp|Q96A49|SYAP1_HUMAN 1 1401.7351 1.53 144415 13285 3 1401.739463 468.2523 Synapse-associated protein 1 OS=Homo sapiens OX=9606 GN=SYAP1 PE=1 SV=1 4.32 2533.6 - 261237 - - - 3.0947 - 1.51 0.33 - 67.1 1 2 1 0.0043 13 0 0 0 5.43E+06 3.55E+06 - - - 3.3353 1 221125_WJC_METTL3_EV_vs_WT_F10.13286.13286.3 1.80E-07 Oct-92 R.QDHPSSMGVYGQESGGFSGPGENR[166.11].S "sp|Q01844|EWS_HUMAN,tr|B0QYK0|B0QYK0_HUMAN" 2 2489.0541 0.59 144416 13286 3 2489.049578 830.692 RNA-binding protein EWS OS=Homo sapiens OX=9606 GN=EWSR1 PE=1 SV=1 4.65 2533.8 - 122976 - - - -1.8308 - 2.564 0.637 - 89.3 1 2 0 -0.0046 24 0 0 0 1.73E+06 2.93E+06 - - - 7.8275 1 221125_WJC_METTL3_EV_vs_WT_F10.13288.13288.2 3.13E-10 30-Dec K.KQISNLQQSISDAEQR.G sp|P04264|K2C1_HUMAN 1 1843.9388 999 144418 13288 2 1843.940942 922.9767 "Keratin, type II cytoskeletal 1 OS=Homo sapiens OX=9606 GN=KRT1 PE=1 SV=6" 6.07 2534 - 105329 - - - 1.1595 - 2.74 0.669 - 384.7 1 2 0 0.0021 16 0 0 0 1.41E+06 0.00E+00 - - - 6.4597 1 221125_WJC_METTL3_EV_vs_WT_F10.13291.13291.3 1.64E-10 25/80 R.KGSLESPATDVFGSTEEGEKR.W sp|O00232|PSD12_HUMAN 1 2223.0655 0.76 144419 13291 3 2223.070597 742.0291 26S proteasome non-ATPase regulatory subunit 12 OS=Homo sapiens OX=9606 GN=PSMD12 PE=1 SV=3 4.59 2534.5 - 281226 - - - 2.2833 - 4.482 0.658 - 768.9 1 2 0 0.0051 21 0 0 0 1.80E+07 2.36E+07 - - - 9.471 1 221125_WJC_METTL3_EV_vs_WT_F10.13293.13293.3 1.55E-20 29/68 R.HYNEEGSQVYNDAHILEK.L "sp|Q86U86|PB1_HUMAN,tr|H0Y5B5|H0Y5B5_HUMAN,tr|E7EVG2|E7EVG2_HUMAN" 3 2144.9763 1.69 144421 13293 3 2144.983264 715.9994 Protein polybromo-1 OS=Homo sapiens OX=9606 GN=PBRM1 PE=1 SV=1 4.8 2534.7 - 2.31E+06 - - - 3.2411 - 5.304 0.789 - 1549.9 1 2 0 0.007 18 0 0 0 2.88E+07 1.70E+07 - - - 11.4893 1 221125_WJC_METTL3_EV_vs_WT_F10.13296.13296.3 1.95E-13 13/88 R.GHETC[160.03]PDDPC[160.03]EDPGPTPPVQLAK.N "sp|Q9HCH0|NCK5L_HUMAN,tr|H7C1V4|H7C1V4_HUMAN" 2 2516.0948 4.04 144424 13296 3 2516.096941 839.7055 Nck-associated protein 5-like OS=Homo sapiens OX=9606 GN=NCKAP5L PE=1 SV=3 4.1 2535.1 - 121181 - - - 0.8553 - 2.849 0.764 - 136.4 1 2 0 0.0022 23 0 0 0 2.05E+06 5.08E+05 - - - 9.5134 0.9998 221125_WJC_METTL3_EV_vs_WT_F10.13303.13303.3 2.11E-07 Dec-64 R.DSAYQSITHYRPVSASR.S "sp|P50402|EMD_HUMAN,tr|A0A804HIV7|A0A804HIV7_HUMAN,tr|Q5HY57|Q5HY57_HUMAN" 3 1936.9391 1.4 144429 13303 3 1936.947153 646.6537 Emerin OS=Homo sapiens OX=9606 GN=EMD PE=1 SV=1 8.6 2536.1 - 472934 - - - 4.138 - 2.269 0.543 - 202.2 1 2 0 0.008 17 0 0 0 3.48E+07 2.49E+07 - - - 6.6616 1 221125_WJC_METTL3_EV_vs_WT_F10.13304.13304.3 0.000124 26/80 R.K[136.11]GSLESPATDVFGSTEEGEK[136.11]R[166.11].W sp|O00232|PSD12_HUMAN 1 2249.1022 0.76 144430 13304 3 2249.106986 750.708 26S proteasome non-ATPase regulatory subunit 12 OS=Homo sapiens OX=9606 GN=PSMD12 PE=1 SV=3 4.59 2536.2 - 450204 - - - 2.132 - 5.422 0.644 - 931.3 1 2 0 0.0048 21 0 0 0 1.79E+07 2.36E+07 - - - 9.7714 0.9994 221125_WJC_METTL3_EV_vs_WT_F10.13305.13305.4 7.27E-06 9/144 K.TQKPPQKPAPAVVSVTPAVKDPLVK.K "sp|Q96CB8|INT12_HUMAN,tr|A0A087WXN4|A0A087WXN4_HUMAN" 2 2594.516 1.61 144431 13305 4 2594.525977 649.6363 Integrator complex subunit 12 OS=Homo sapiens OX=9606 GN=INTS12 PE=1 SV=1 10 2536.3 - 242955 - - - 3.8612 - 1.996 0.552 - 34.8 1 2 1 0.01 25 0 0 0 3.94E+06 2.44E+06 - - - 4.2477 0.9999 221125_WJC_METTL3_EV_vs_WT_F10.13309.13309.4 1.19E-10 25/120 R.K[136.11]GSLESPATDVFGSTEEGEK[136.11]R[166.11].W sp|O00232|PSD12_HUMAN 1 2249.1022 0.83 144433 13309 4 2249.112235 563.2828 26S proteasome non-ATPase regulatory subunit 12 OS=Homo sapiens OX=9606 GN=PSMD12 PE=1 SV=3 4.59 2536.9 - 1.93E+06 - - - 4.4658 - 4.325 0.606 - 619 1 2 0 0.01 21 0 0 0 6.14E+07 7.35E+07 - - - 4.982 0.9989 221125_WJC_METTL3_EV_vs_WT_F10.13311.13311.4 0.00605 Aug-90 R.KEPFFHGHDNYDQLVR.L "sp|P68400|CSK21_HUMAN,tr|A0A2R8YFU2|A0A2R8YFU2_HUMAN,tr|A0A2R8YD58|A0A2R8YD58_HUMAN,tr|A0A2R8YF43|A0A2R8YF43_HUMAN,tr|A0A2R8Y5A0|A0A2R8Y5A0_HUMAN,tr|A0A2R8YDP2|A0A2R8YDP2_HUMAN,tr|E7EU96|E7EU96_HUMAN" 7 2000.9493 1.98 144435 13311 4 2000.956019 501.2446 Casein kinase II subunit alpha OS=Homo sapiens OX=9606 GN=CSNK2A1 PE=1 SV=1 6 2537.1 - 221259 - - - 3.3534 - 1.567 0.374 - 59.9 1 2 0 0.0067 16 0 0 0 9.82E+06 4.96E+06 - - - 2.6377 1 221125_WJC_METTL3_EV_vs_WT_F10.13313.13313.3 3.21E-10 14/64 Y.VHYEIDAC[160.03]MDSEAPGSK[136.11].D "sp|Q86U44|MTA70_HUMAN,tr|H0YFV6|H0YFV6_HUMAN" 2 1915.8172 0.001 144437 13313 3 1916.824697 639.613 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 4.31 2537.4 - 114767 - - - 525.9025 - 3.071 0.698 - 244.5 1 1 0 1.0075 17 0 0 0 0.00E+00 5.55E+06 - - - 8.8774 0.9999 221125_WJC_METTL3_EV_vs_WT_F10.13317.13317.3 2.12E-10 19/68 K.C[160.03]ENIQKPLSSVQENIQQK.S "sp|P52732|KIF11_HUMAN,tr|A0A7I2V3A9|A0A7I2V3A9_HUMAN" 2 2142.0739 4.69 144439 13317 3 2142.080381 715.0319 Kinesin-like protein KIF11 OS=Homo sapiens OX=9606 GN=KIF11 PE=1 SV=2 6.14 2537.9 - 1.50E+06 - - - 3.0176 - 3.702 0.528 - 479.2 1 2 0 0.0065 18 0 0 0 9.48E+08 2.02E+08 - - - 7.6841 0.9996 221125_WJC_METTL3_EV_vs_WT_F10.13318.13318.3 3.66E-07 15/64 R.DSAYQSITHYR[166.11]PVSASR[166.11].S "sp|P50402|EMD_HUMAN,tr|A0A804HIV7|A0A804HIV7_HUMAN,tr|Q5HY57|Q5HY57_HUMAN" 3 1956.9557 1.4 144440 13318 3 1956.966279 653.3258 Emerin OS=Homo sapiens OX=9606 GN=EMD PE=1 SV=1 8.6 2538.1 - 998915 - - - 5.4171 - 2.376 0.576 - 278.6 1 2 0 0.0106 17 0 0 0 3.48E+07 2.49E+07 - - - 7.1452 0.9988 221125_WJC_METTL3_EV_vs_WT_F10.13319.13319.3 0.000774 Oct-64 K.MAPVPLDDSNRPASLTK.D "sp|Q9NYF8|BCLF1_HUMAN,tr|E9PKI6|E9PKI6_HUMAN,tr|A0A1W2PQ43|A0A1W2PQ43_HUMAN,tr|E9PK91|E9PK91_HUMAN,tr|E9PJA7|E9PJA7_HUMAN,tr|E9PK09|E9PK09_HUMAN,tr|E9PQN2|E9PQN2_HUMAN" 7 1810.9247 2.67 144441 13319 3 1810.930351 604.6489 Bcl-2-associated transcription factor 1 OS=Homo sapiens OX=9606 GN=BCLAF1 PE=1 SV=2 5.71 2538.2 - 347695 - - - 3.1017 - 1.876 0.373 - 75.6 1 2 0 0.0056 17 0 0 0 1.39E+07 5.19E+06 - - - 4.2864 0.9996 221125_WJC_METTL3_EV_vs_WT_F10.13321.13321.3 0.00477 Aug-36 R.K[136.11]QDSGHLDLR[166.11].N "sp|Q86U44|MTA70_HUMAN,tr|B4E349|B4E349_HUMAN,tr|F5H6D8|F5H6D8_HUMAN,tr|B4DTN4|B4DTN4_HUMAN" 4 1185.6221 0.02 144443 13321 3 1185.625371 396.2146 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 6.75 2538.4 - 154605 - - - 2.7547 - 1.65 0.442 - 96.1 1 2 0 0.0033 10 0 0 0 1.17E+05 5.74E+06 - - - 4.9294 0.9996 221125_WJC_METTL3_EV_vs_WT_F10.13322.13322.3 1.32E-05 Aug-92 R.QDHPSSMGVYGQESGGFSGPGENR.S "sp|Q01844|EWS_HUMAN,tr|B0QYK0|B0QYK0_HUMAN" 2 2479.0459 0.5 144444 13322 3 2479.058419 827.3559 RNA-binding protein EWS OS=Homo sapiens OX=9606 GN=EWSR1 PE=1 SV=1 4.65 2538.6 - 84147.8 - - - 5.064 - 2.13 0.587 - 67.8 1 2 0 0.0126 24 0 0 0 3.13E+06 6.21E+06 - - - 6.8372 0.9922 221125_WJC_METTL3_EV_vs_WT_F10.13326.13326.4 0.000592 15/132 S.GGPK[136.11]PSTASAVPELATDPELEK[136.11]K[136.11].L "sp|Q86U44|MTA70_HUMAN,tr|B4E349|B4E349_HUMAN,tr|F5H6D8|F5H6D8_HUMAN,tr|H0YFV6|H0YFV6_HUMAN,tr|B4DTN4|B4DTN4_HUMAN" 5 2345.2541 0.08 144446 13326 4 2345.257236 587.3208 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 4.87 2539.1 - 458687 - - - 1.3555 - 2.585 0.457 - 97.1 1 1 0 0.0032 23 0 0 0 1.62E+06 2.13E+07 - - - 3.5105 0.9956 221125_WJC_METTL3_EV_vs_WT_F10.13333.13333.4 0.00143 Aug-90 K.KHLEINPDHPIVETLR.Q sp|P08238|HS90B_HUMAN 1 1910.0374 0.97 144451 13333 4 1910.0441 478.5166 Heat shock protein HSP 90-beta OS=Homo sapiens OX=9606 GN=HSP90AB1 PE=1 SV=4 6.01 2540.1 - 157910 - - - 3.5099 - 1.913 0.3 - 48.2 1 2 0 0.0067 16 0 0 0 1.12E+07 1.16E+07 - - - 2.0638 0.9995 221125_WJC_METTL3_EV_vs_WT_F10.13341.13341.4 0.000779 Oct-90 K.K[136.11]HLEINPDHPIVETLR[166.11].Q sp|P08238|HS90B_HUMAN 1 1928.0599 0.96 144457 13341 4 1928.06598 483.0222 Heat shock protein HSP 90-beta OS=Homo sapiens OX=9606 GN=HSP90AB1 PE=1 SV=4 6.01 2541.2 - 214119 - - - 3.1711 - 2.023 0.41 - 74.8 1 2 0 0.0061 16 0 0 0 1.17E+07 1.21E+07 - - - 3.0411 0.9993 221125_WJC_METTL3_EV_vs_WT_F10.13344.13344.4 0.0051 Oct-78 R.QRPSEIKDYSPYFK.T sp|P08779|K1C16_HUMAN 1 1756.8784 1157.8 144458 13344 4 1756.881112 440.2269 "Keratin, type I cytoskeletal 16 OS=Homo sapiens OX=9606 GN=KRT16 PE=1 SV=4" 8.43 2541.6 - 194980 - - - 1.5237 - 1.6 0.406 - 86.4 1 2 1 0.0027 14 0 0 0 3.12E+07 2.70E+04 - - - 2.9301 1 221125_WJC_METTL3_EV_vs_WT_F10.13348.13348.2 4.30E-11 14/34 K.C[160.03]ENIQKPLSSVQENIQQK.S "sp|P52732|KIF11_HUMAN,tr|A0A7I2V3A9|A0A7I2V3A9_HUMAN" 2 2142.0739 10.99 144462 13348 2 2142.076307 1072.0442 Kinesin-like protein KIF11 OS=Homo sapiens OX=9606 GN=KIF11 PE=1 SV=2 6.14 2542.1 - 207598 - - - 1.1157 - 3.022 0.699 - 465.1 1 2 0 0.0024 18 0 0 0 8.77E+06 7.98E+05 - - - 6.922 0.9923 221125_WJC_METTL3_EV_vs_WT_F10.13353.13353.4 0.000258 13/144 P.TSGGPK[136.11]PSTASAVPELATDPELEK[136.11]K[136.11].L "sp|Q86U44|MTA70_HUMAN,tr|B4E349|B4E349_HUMAN,tr|F5H6D8|F5H6D8_HUMAN,tr|H0YFV6|H0YFV6_HUMAN,tr|B4DTN4|B4DTN4_HUMAN" 5 2533.3338 0.02 144465 13353 4 2533.335466 634.3407 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 4.87 2542.8 - 327526 - - - 0.6718 - 2.806 0.45 - 73.8 1 1 0 0.0017 25 0 0 0 1.02E+06 4.47E+07 - - - 3.4706 0.9999 221125_WJC_METTL3_EV_vs_WT_F10.13368.13368.4 0.000103 14/180 K.KVASGVLSPPPAAPPPSSSSVPEAGGPPIKK.Q "sp|Q8IXM2|BAP18_HUMAN,tr|H0YIS7|H0YIS7_HUMAN,tr|F8W038|F8W038_HUMAN,tr|F8W1H0|F8W1H0_HUMAN" 4 2905.5913 2.2 144477 13368 4 2905.600775 727.4051 Chromatin complexes subunit BAP18 OS=Homo sapiens OX=9606 GN=BAP18 PE=1 SV=1 9.7 2544.6 - 331584 - - - 3.2579 - 2.561 0.555 - 61.2 1 2 0 0.0095 31 0 0 0 2.59E+07 1.17E+07 - - - 4.3399 0.9988 221125_WJC_METTL3_EV_vs_WT_F10.13370.13370.3 1.13E-07 24/92 T.SGGPK[136.11]PSTASAVPELATDPELEK[136.11]K[136.11].L "sp|Q86U44|MTA70_HUMAN,tr|B4E349|B4E349_HUMAN,tr|F5H6D8|F5H6D8_HUMAN,tr|H0YFV6|H0YFV6_HUMAN,tr|B4DTN4|B4DTN4_HUMAN" 5 2432.2861 0.001 144479 13370 3 2432.28323 811.7693 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 4.87 2544.9 - 601694 - - - -1.1738 - 3.596 0.594 - 571.5 1 1 0 -0.0029 24 0 0 0 0.00E+00 2.54E+07 - - - 8.1342 0.9857 221125_WJC_METTL3_EV_vs_WT_F10.13376.13376.3 0.00125 15/88 S.GGPK[136.11]PSTASAVPELATDPELEK[136.11]K[136.11].L "sp|Q86U44|MTA70_HUMAN,tr|B4E349|B4E349_HUMAN,tr|F5H6D8|F5H6D8_HUMAN,tr|H0YFV6|H0YFV6_HUMAN,tr|B4DTN4|B4DTN4_HUMAN" 5 2345.2541 0.02 144483 13376 3 2345.24777 782.7586 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 4.87 2545.6 - 274476 - - - -2.6807 - 2.724 0.457 - 185.1 1 1 0 -0.0063 23 0 0 0 7.16E+04 4.28E+06 - - - 5.9842 1 221125_WJC_METTL3_EV_vs_WT_F10.13377.13377.3 2.26E-08 9/112 K.IC[160.03]EEETGSTSIQAADSTAVNGSITPTDK[136.11]K[136.11].L "sp|Q49A26|GLYR1_HUMAN,tr|K7EPU6|K7EPU6_HUMAN" 2 3025.4369 1.36 144484 13377 3 3025.438024 1009.4862 Putative oxidoreductase GLYR1 OS=Homo sapiens OX=9606 GN=GLYR1 PE=1 SV=4 4.18 2545.8 - 119459 - - - 0.3864 - 2.124 0.702 - 56.5 1 2 0 0.0012 29 0 0 0 4.55E+06 3.35E+06 - - - 8.0994 0.998 221125_WJC_METTL3_EV_vs_WT_F10.13389.13389.4 5.32E-08 32/138 T.SGGPK[136.11]PSTASAVPELATDPELEK[136.11]K[136.11].L "sp|Q86U44|MTA70_HUMAN,tr|B4E349|B4E349_HUMAN,tr|F5H6D8|F5H6D8_HUMAN,tr|H0YFV6|H0YFV6_HUMAN,tr|B4DTN4|B4DTN4_HUMAN" 5 2432.2861 0 144490 13389 4 2432.287145 609.0788 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 4.87 2547.4 - 5.36E+06 - - - 0.4358 - 4.69 0.566 - 655.3 1 1 0 0.0011 24 0 0 0 1.97E+05 1.30E+08 - - - 4.6482 0.999 221125_WJC_METTL3_EV_vs_WT_F10.13401.13401.2 0.0408 16-Jul K.SPLQSVVVR.R "sp|Q9Y2W1|TR150_HUMAN,tr|A0A3B3ITZ9|A0A3B3ITZ9_HUMAN" 2 983.5764 1.54 144499 13401 2 983.577052 492.7955 Thyroid hormone receptor-associated protein 3 OS=Homo sapiens OX=9606 GN=THRAP3 PE=1 SV=2 9.47 2548.9 - 85827.3 - - - 0.6832 - 1.459 0.321 - 138.4 1 2 0 0.0007 9 0 0 0 7.52E+06 4.88E+06 - - - 2.5045 0.9999 221125_WJC_METTL3_EV_vs_WT_F10.13406.13406.4 4.91E-05 Oct-90 R.DLLHNEDRHDDYFQER.N sp|Q8N684|CPSF7_HUMAN 1 2100.9249 1.13 144502 13406 4 2100.923282 526.2385 Cleavage and polyadenylation specificity factor subunit 7 OS=Homo sapiens OX=9606 GN=CPSF7 PE=1 SV=1 4.51 2549.6 - 280362 - - - -0.7916 - 2.087 0.51 - 77.4 1 2 1 -0.0017 16 0 0 0 3.56E+06 3.15E+06 - - - 3.9237 0.997 221125_WJC_METTL3_EV_vs_WT_F10.13415.13415.3 0.0345 Oct-36 R.R[166.11]K[136.11]PFYPALIR[166.11].Y "sp|O00746|NDKM_HUMAN,tr|Q4TT34|Q4TT34_HUMAN,tr|H0Y6J0|H0Y6J0_HUMAN,tr|F2Z2X0|F2Z2X0_HUMAN,tr|A2IDC9|A2IDC9_HUMAN" 5 1287.781 1.75 144509 13415 3 1287.783382 430.2676 "Nucleoside diphosphate kinase, mitochondrial OS=Homo sapiens OX=9606 GN=NME4 PE=1 SV=1" 11 2550.9 - 264280 - - - 1.8481 - 1.611 0.27 - 150.5 1 2 0 0.0024 10 0 0 0 1.14E+07 6.50E+06 - - - 2.9422 0.9903 221125_WJC_METTL3_EV_vs_WT_F10.13419.13419.4 7.51E-05 16/120 R.LELREENPLNHNVVDASTAHR.L "sp|Q6W2J9|BCOR_HUMAN,tr|H7BZ37|H7BZ37_HUMAN,tr|H7C2V9|H7C2V9_HUMAN,tr|A0A5F9ZGX7|A0A5F9ZGX7_HUMAN,tr|H7BYY2|H7BYY2_HUMAN,tr|H7C231|H7C231_HUMAN" 6 2413.2098 0.21 144511 13419 4 2413.223265 604.3097 BCL-6 corepressor OS=Homo sapiens OX=9606 GN=BCOR PE=1 SV=1 5.36 2551.5 - 223779 - - - 5.5656 - 2.989 0.401 - 171.6 1 2 1 0.0134 21 0 0 0 4.74E+07 2.22E+08 - - - 3.0746 1 221125_WJC_METTL3_EV_vs_WT_F10.13423.13423.3 8.44E-09 10/112 K.IC[160.03]EEETGSTSIQAADSTAVNGSITPTDKK.L "sp|Q49A26|GLYR1_HUMAN,tr|K7EPU6|K7EPU6_HUMAN" 2 3009.4085 1.36 144515 13423 3 3009.415893 1004.1434 Putative oxidoreductase GLYR1 OS=Homo sapiens OX=9606 GN=GLYR1 PE=1 SV=4 4.18 2552 - 177242 - - - 2.4716 - 2.578 0.673 - 76.3 1 2 0 0.0074 29 0 0 0 4.55E+06 3.35E+06 - - - 8.22 0.9972 221125_WJC_METTL3_EV_vs_WT_F10.13430.13430.4 0.0183 Sep-90 R.DLLHNEDR[166.11]HDDYFQER[166.11].N sp|Q8N684|CPSF7_HUMAN 1 2120.9415 1.13 144520 13430 4 2120.948181 531.2426 Cleavage and polyadenylation specificity factor subunit 7 OS=Homo sapiens OX=9606 GN=CPSF7 PE=1 SV=1 4.51 2553 - 228561 - - - 3.1571 - 1.842 0.387 - 59.6 1 2 1 0.0067 16 0 0 0 3.63E+06 3.23E+06 - - - 2.8078 0.994 221125_WJC_METTL3_EV_vs_WT_F10.13438.13438.4 0.00199 7/114 R.ASFNHFDKDHGGALGPEEFK.A "sp|O43707|ACTN4_HUMAN,tr|F5GXS2|F5GXS2_HUMAN" 2 2202.013 1.67 144526 13438 4 2202.018923 551.5105 Alpha-actinin-4 OS=Homo sapiens OX=9606 GN=ACTN4 PE=1 SV=2 5.31 2554 - 195054 - - - 2.6757 - 1.791 0.327 - 25.2 1 2 1 0.0059 20 0 0 0 3.04E+07 1.83E+07 - - - 2.2654 0.9979 221125_WJC_METTL3_EV_vs_WT_F10.13439.13439.3 1.31E-05 16/96 P.TSGGPK[136.11]PSTASAVPELATDPELEK[136.11]K[136.11].L "sp|Q86U44|MTA70_HUMAN,tr|B4E349|B4E349_HUMAN,tr|F5H6D8|F5H6D8_HUMAN,tr|H0YFV6|H0YFV6_HUMAN,tr|B4DTN4|B4DTN4_HUMAN" 5 2533.3338 0.13 144527 13439 3 2533.335779 845.4519 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 4.87 2554.1 - 191096 - - - 0.7954 - 2.789 0.551 - 193.1 1 1 0 0.002 25 0 0 0 3.71E+05 2.75E+06 - - - 7.0423 1 221125_WJC_METTL3_EV_vs_WT_F10.13443.13443.3 1.81E-11 11/124 K.EAPAEGEAAEPGSPTAAEGEAASAASSTSSPK.A sp|P29966|MARCS_HUMAN 1 2914.2952 1.39 144531 13443 3 2914.303902 972.439 Myristoylated alanine-rich C-kinase substrate OS=Homo sapiens OX=9606 GN=MARCKS PE=1 SV=4 3.9 2554.7 - 81802.1 - - - 2.9863 - 3.098 0.685 - 86.5 1 2 0 0.0087 32 0 0 0 3.88E+07 2.78E+07 - - - 8.7761 0.9999 221125_WJC_METTL3_EV_vs_WT_F10.13447.13447.4 8.33E-06 14/138 K.LNSHETTITQQSVSDSHLAELQEK.L "sp|Q5VU43|MYOME_HUMAN,tr|E9PQG4|E9PQG4_HUMAN,tr|A0A087WX83|A0A087WX83_HUMAN,tr|A0A075B749|A0A075B749_HUMAN" 4 2694.3097 1.89 144533 13447 4 2694.31282 674.5847 Myomegalin OS=Homo sapiens OX=9606 GN=PDE4DIP PE=1 SV=3 4.8 2555.2 - 288195 - - - 1.1702 - 2.537 0.462 - 70.2 1 2 0 0.0032 24 0 0 0 3.02E+06 1.60E+06 - - - 3.5452 0.9994 221125_WJC_METTL3_EV_vs_WT_F10.13450.13450.2 0.000636 Sep-32 R.AIGGGLSSVGGGSSTIK.Y "sp|P48668|K2C6C_HUMAN,sp|P02538|K2C6A_HUMAN" 2 1446.7678 20.77 144536 13450 2 1446.768053 724.3912 "Keratin, type II cytoskeletal 6C OS=Homo sapiens OX=9606 GN=KRT6C PE=1 SV=3" 8.8 2555.6 - 115833 - - - 0.1597 - 1.806 0.32 - 184.5 1 2 0 0.0002 17 0 0 0 1.86E+06 8.94E+04 - - - 2.8577 1 221125_WJC_METTL3_EV_vs_WT_F10.13453.13453.3 3.55E-16 26/112 R.VPSAAC[160.03]PPFPPHGAPVSASSSSSSPGGSR.G sp|Q9H7S9|ZN703_HUMAN 1 2734.2769 5.87 144537 13453 3 2734.277771 912.4329 Zinc finger protein 703 OS=Homo sapiens OX=9606 GN=ZNF703 PE=1 SV=1 8.23 2556.1 - 611557 - - - 0.3087 - 4.213 0.745 - 382.5 1 2 0 0.0008 29 0 0 0 7.47E+07 1.27E+07 - - - 10.1545 0.8099 221125_WJC_METTL3_EV_vs_WT_F10.13464.13464.4 0.096 18/120 R.LELR[166.11]EENPLNHNVVDASTAHR[166.11].L "sp|Q6W2J9|BCOR_HUMAN,tr|H7BZ37|H7BZ37_HUMAN,tr|H7C2V9|H7C2V9_HUMAN,tr|A0A5F9ZGX7|A0A5F9ZGX7_HUMAN,tr|H7BYY2|H7BYY2_HUMAN,tr|H7C231|H7C231_HUMAN" 6 2433.2264 0.2 144544 13464 4 2433.233535 609.3139 BCL-6 corepressor OS=Homo sapiens OX=9606 GN=BCOR PE=1 SV=1 5.36 2557.3 - 3.41E+06 - - - 2.943 - 1.994 0.171 - 83 1 2 1 0.0072 21 0 0 0 4.72E+07 2.31E+08 - - - 0.9406 1 221125_WJC_METTL3_EV_vs_WT_F10.13465.13465.3 3.23E-12 19/88 R.VEHNQSYSQAGITETEWTSGSSK.G sp|P42167|LAP2B_HUMAN 1 2525.1306 1.6 144545 13465 3 2525.128878 842.7175 "Lamina-associated polypeptide 2, isoforms beta\gamma OS=Homo sapiens OX=9606 GN=TMPO PE=1 SV=2" 4.75 2557.5 - 573447 - - - -0.6978 - 3.638 0.691 - 432.5 1 2 0 -0.0018 23 0 0 0 2.71E+07 1.69E+07 - - - 9.2731 0.9962 221125_WJC_METTL3_EV_vs_WT_F10.13472.13472.3 3.18E-07 14/52 D.DAHPTLVTYADHSK[136.11].L "sp|Q86U44|MTA70_HUMAN,tr|F5H6D8|F5H6D8_HUMAN,tr|H0YFV6|H0YFV6_HUMAN,tr|B4DTN4|B4DTN4_HUMAN" 4 1561.7616 0 144549 13472 3 1561.758517 521.5945 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 5.98 2558.3 - 278926 - - - -1.9875 - 2.617 0.534 - 206.5 1 1 0 -0.0031 14 0 0 0 5.52E+05 1.99E+08 - - - 7.0493 1 221125_WJC_METTL3_EV_vs_WT_F10.13478.13478.3 9.10E-09 19/56 Q.DDAHPTLVTYADHSK[136.11].L "sp|Q86U44|MTA70_HUMAN,tr|F5H6D8|F5H6D8_HUMAN,tr|H0YFV6|H0YFV6_HUMAN,tr|B4DTN4|B4DTN4_HUMAN" 4 1676.7886 0.01 144552 13478 3 1676.787383 559.9368 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 5.13 2559 - 4.54E+06 - - - -0.7043 - 3.09 0.633 - 543.7 1 1 0 -0.0012 15 0 0 0 2.09E+07 1.68E+09 - - - 8.5408 1 221125_WJC_METTL3_EV_vs_WT_F10.13484.13484.2 6.15E-08 19/38 K.R[166.11]GLLQDDAHPTLVTYADHSK[136.11].L "sp|Q86U44|MTA70_HUMAN,tr|F5H6D8|F5H6D8_HUMAN,tr|H0YFV6|H0YFV6_HUMAN,tr|B4DTN4|B4DTN4_HUMAN" 4 2254.1461 0.001 144555 13484 2 2254.137939 1128.0803 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 5.99 2559.7 - 768862 - - - -3.6271 - 3.511 0.66 - 490.7 1 2 0 -0.0082 20 0 0 0 0.00E+00 4.38E+08 - - - 7.0009 1 221125_WJC_METTL3_EV_vs_WT_F10.13510.13510.3 3.01E-11 24/72 K.HTGC[160.03]C[160.03]GDNDPIDVC[160.03]EIGSK[136.11].V "sp|Q15181|IPYR_HUMAN,tr|Q5SQT6|Q5SQT6_HUMAN" 2 2140.8703 0.59 144563 13510 3 2140.864368 714.6307 Inorganic pyrophosphatase OS=Homo sapiens OX=9606 GN=PPA1 PE=1 SV=2 4.22 2563.2 - 2.33E+06 - - - -2.7891 - 2.471 0.719 - 413.7 1 2 0 -0.006 19 0 0 0 7.47E+07 1.26E+08 - - - 8.777 0.9808 221125_WJC_METTL3_EV_vs_WT_F10.13521.13521.2 5.07E-07 20-Dec H.PTLVTYADHSK[136.11].L "sp|Q86U44|MTA70_HUMAN,tr|F5H6D8|F5H6D8_HUMAN,tr|H0YFV6|H0YFV6_HUMAN,tr|B4DTN4|B4DTN4_HUMAN" 4 1238.6387 0.29 144564 13521 2 1238.635308 620.3266 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 7.16 2565 - 1.79E+06 - - - -2.6997 - 2.316 0.56 - 519.7 1 1 0 -0.0033 11 0 0 0 3.22E+07 1.11E+08 - - - 5.4481 1 221125_WJC_METTL3_EV_vs_WT_F10.13531.13531.3 3.36E-05 24/76 K.R[166.11]GLLQDDAHPTLVTYADHSK[136.11].L "sp|Q86U44|MTA70_HUMAN,tr|F5H6D8|F5H6D8_HUMAN,tr|H0YFV6|H0YFV6_HUMAN,tr|B4DTN4|B4DTN4_HUMAN" 4 2254.1461 0 144565 13531 3 2254.138444 752.3893 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 5.99 2566.6 - 1.98E+08 - - - -3.4031 - 4.101 0.621 - 754.5 1 2 0 -0.0077 20 0 0 0 3.21E+07 1.65E+10 - - - 8.8851 1 221125_WJC_METTL3_EV_vs_WT_F10.13535.13535.4 7.93E-08 19/114 K.R[166.11]GLLQDDAHPTLVTYADHSK[136.11].L "sp|Q86U44|MTA70_HUMAN,tr|F5H6D8|F5H6D8_HUMAN,tr|H0YFV6|H0YFV6_HUMAN,tr|B4DTN4|B4DTN4_HUMAN" 4 2254.1461 0.01 144568 13535 4 2254.14109 564.5438 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 5.99 2567 - 1.21E+09 - - - -2.2292 - 3.74 0.608 - 411.1 1 2 0 -0.005 20 0 0 0 6.19E+08 9.09E+10 - - - 4.9576 1 221125_WJC_METTL3_EV_vs_WT_F10.13539.13539.3 4.14E-09 21/56 R.STSHK[136.11]PDEIYGMIER[166.11].L sp|Q86U44|MTA70_HUMAN 1 1779.8581 0 144569 13539 3 1779.85516 594.2933 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 5.42 2567.6 - 7.14E+06 - - - -1.626 - 3.495 0.51 - 552.1 1 2 0 -0.0029 15 0 0 0 3.69E+07 2.14E+10 - - - 7.4904 0.998 221125_WJC_METTL3_EV_vs_WT_F10.13540.13540.4 1.86E-05 17/84 R.STSHK[136.11]PDEIYGMIER[166.11].L sp|Q86U44|MTA70_HUMAN 1 1779.8581 0 144570 13540 4 1779.849709 445.9718 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 5.42 2567.6 - 2.92E+06 - - - -4.6886 - 2.865 0.371 - 209.6 1 2 0 -0.0083 15 0 0 0 3.22E+07 9.76E+09 - - - 2.8295 1 221125_WJC_METTL3_EV_vs_WT_F10.13560.13560.2 2.13E-08 19/28 R.STSHK[136.11]PDEIYGMIER[166.11].L sp|Q86U44|MTA70_HUMAN 1 1779.8581 0.001 144576 13560 2 1779.848935 890.9363 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 5.42 2570.5 - 2.90E+06 - - - -5.1234 - 2.626 0.644 - 734.7 1 2 0 -0.0091 15 0 0 0 0.00E+00 1.28E+09 - - - 6.1684 0.9999 221125_WJC_METTL3_EV_vs_WT_F10.13561.13561.3 1.08E-06 16/40 R.LVNHFVEEFK[136.11]R[166.11].K "sp|P0DMV8|HS71A_HUMAN,sp|P0DMV9|HS71B_HUMAN,tr|V9GZ37|V9GZ37_HUMAN,tr|A0A0G2JIW1|A0A0G2JIW1_HUMAN" 4 1434.7739 0.06 144577 13561 3 1434.769153 479.2652 Heat shock 70 kDa protein 1A OS=Homo sapiens OX=9606 GN=HSPA1A PE=1 SV=1 6.76 2570.6 - 2.58E+06 - - - -3.2765 - 2.71 0.488 - 403.6 1 2 0 -0.0047 11 0 0 0 6.84E+06 1.07E+08 - - - 6.8116 0.9999 221125_WJC_METTL3_EV_vs_WT_F10.13588.13588.2 9.05E-08 15/22 R.FLEQQNQVLQTK.W "sp|Q7Z794|K2C1B_HUMAN,sp|P04264|K2C1_HUMAN,sp|P35908|K22E_HUMAN" 3 1474.778 999 144585 13588 2 1474.776584 738.3963 "Keratin, type II cytoskeletal 1b OS=Homo sapiens OX=9606 GN=KRT77 PE=1 SV=3" 6 2574.2 - 1.67E+06 - - - -0.9554 - 2.528 0.572 - 702 1 2 0 -0.0014 12 0 0 0 4.28E+07 0.00E+00 - - - 5.7056 0.9979 221125_WJC_METTL3_EV_vs_WT_F10.13634.13634.3 1.15E-06 15/48 T.SHK[136.11]PDEIYGMIER[166.11].L sp|Q86U44|MTA70_HUMAN 1 1591.7783 0 144603 13634 3 1591.777132 531.6001 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 5.42 2580.1 - 790922 - - - -0.7633 - 2.86 0.506 - 345.5 1 1 0 -0.0012 13 0 0 0 4.89E+04 1.83E+07 - - - 7.0301 1 221125_WJC_METTL3_EV_vs_WT_F10.13640.13640.4 7.76E-10 30/144 R.YYEVLGAAATTDYNNNHEGREEDQR.L "sp|P46379|BAG6_HUMAN,tr|A0A7I2V508|A0A7I2V508_HUMAN,tr|A0A0G2JJM1|A0A0G2JJM1_HUMAN,tr|X6REW1|X6REW1_HUMAN,tr|A0A7P0MQS5|A0A7P0MQS5_HUMAN,tr|F6S6P2|F6S6P2_HUMAN,tr|A0A0G2JL47|A0A0G2JL47_HUMAN,tr|A0A024RCR6|A0A024RCR6_HUMAN,tr|A0A0G2JK23|A0A0G2JK23_HUMAN" 9 2914.2754 1.61 144605 13640 4 2914.269169 729.5761 Large proline-rich protein BAG6 OS=Homo sapiens OX=9606 GN=BAG6 PE=1 SV=2 4.35 2580.9 - 2.37E+06 - - - -2.1405 - 3.439 0.628 - 387.8 1 2 1 -0.0062 25 0 0 0 9.07E+07 5.63E+07 - - - 5.0833 0.9799 221125_WJC_METTL3_EV_vs_WT_F10.13644.13644.4 0.0323 22/162 P.TAPTSGGPK[136.11]PSTASAVPELATDPELEK[136.11]K[136.11].L "sp|Q86U44|MTA70_HUMAN,tr|B4E349|B4E349_HUMAN,tr|F5H6D8|F5H6D8_HUMAN,tr|H0YFV6|H0YFV6_HUMAN,tr|B4DTN4|B4DTN4_HUMAN" 5 2802.4713 0.001 144607 13644 4 2802.465526 701.6251 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 4.87 2581.4 - 1.29E+06 - - - -2.0675 - 3.23 0.407 - 216.4 1 1 0 -0.0058 28 0 0 0 0.00E+00 8.79E+07 - - - 3.131 0.9965 221125_WJC_METTL3_EV_vs_WT_F10.13654.13654.4 4.74E-09 22/156 T.APTSGGPK[136.11]PSTASAVPELATDPELEK[136.11]K[136.11].L "sp|Q86U44|MTA70_HUMAN,tr|B4E349|B4E349_HUMAN,tr|F5H6D8|F5H6D8_HUMAN,tr|H0YFV6|H0YFV6_HUMAN,tr|B4DTN4|B4DTN4_HUMAN" 5 2701.4236 0 144611 13654 4 2701.418753 676.3632 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 4.87 2582.7 - 2.27E+06 - - - -1.8094 - 3.995 0.534 - 197.3 1 1 0 -0.0049 27 0 0 0 1.33E+05 7.11E+07 - - - 4.306 1 221125_WJC_METTL3_EV_vs_WT_F10.13656.13656.3 1.48E-13 26/132 K.GEGESPPVNGTDEAAGATGDAIEPAPPSQGAEAK[136.11].G sp|P49006|MRP_HUMAN 1 3184.4524 1.09 144612 13656 3 3184.446368 1062.4914 MARCKS-related protein OS=Homo sapiens OX=9606 GN=MARCKSL1 PE=1 SV=2 3.71 2582.9 - 1.38E+06 - - - -1.8864 - 4.12 0.695 - 321.1 1 2 0 -0.006 34 0 0 0 1.59E+08 1.46E+08 - - - 9.5443 0.9878 221125_WJC_METTL3_EV_vs_WT_F10.13660.13660.3 0.00182 15/76 K.RGLLQDDAHPTLVTYADHSK[136.11].L "sp|Q86U44|MTA70_HUMAN,tr|F5H6D8|F5H6D8_HUMAN,tr|H0YFV6|H0YFV6_HUMAN,tr|B4DTN4|B4DTN4_HUMAN" 4 2244.1378 - 144614 13660 3 2245.134768 749.0532 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 5.99 2583.4 - 733659 - - - 444.2343 - 2.776 0.38 - 269.6 1 2 0 0.9969 20 0 0 0 - - - - - 4.9775 0.9996 221125_WJC_METTL3_EV_vs_WT_F10.13663.13663.4 0.000392 12/102 K.KYEDIC[160.03]PSTHNMDVPNIK.R "sp|P63241|IF5A1_HUMAN,sp|Q9GZV4|IF5A2_HUMAN,sp|Q6IS14|IF5AL_HUMAN,tr|C9J4W5|C9J4W5_HUMAN,tr|I3L397|I3L397_HUMAN,tr|I3L504|I3L504_HUMAN,tr|C9J7B5|C9J7B5_HUMAN,tr|F8WCJ1|F8WCJ1_HUMAN" 8 2159.998 1.54 144617 13663 4 2159.988027 541.0068 Eukaryotic translation initiation factor 5A-1 OS=Homo sapiens OX=9606 GN=EIF5A PE=1 SV=2 5.38 2583.8 - 434765 - - - -4.6056 - 2.528 0.486 - 110.3 1 2 0 -0.0099 18 0 0 0 2.39E+07 1.56E+07 - - - 3.7711 1 221125_WJC_METTL3_EV_vs_WT_F10.13666.13666.3 7.89E-18 39/132 K.GEGESPPVNGTDEAAGATGDAIEPAPPSQGAEAK.G sp|P49006|MRP_HUMAN 1 3176.4382 1.09 144618 13666 3 3176.437181 1059.82 MARCKS-related protein OS=Homo sapiens OX=9606 GN=MARCKSL1 PE=1 SV=2 3.71 2584.2 - 2.70E+06 - - - -0.3129 - 5.618 0.786 - 917.5 1 2 0 -0.001 34 0 0 0 1.59E+08 1.46E+08 - - - 11.2737 1 221125_WJC_METTL3_EV_vs_WT_F10.13673.13673.3 8.67E-09 14/60 K.AQVQLDSDHLEEDIHR.L "sp|P07197|NFM_HUMAN,tr|E7ESP9|E7ESP9_HUMAN,tr|E7EMV2|E7EMV2_HUMAN" 3 1903.9024 2.69 144622 13673 3 1903.896944 635.6414 Neurofilament medium polypeptide OS=Homo sapiens OX=9606 GN=NEFM PE=1 SV=3 4.42 2585.1 - 346892 - - - -2.8751 - 2.757 0.594 - 220.6 1 2 0 -0.0055 16 0 0 0 2.73E+06 1.02E+06 - - - 7.7631 0.9999 221125_WJC_METTL3_EV_vs_WT_F10.13677.13677.4 2.68E-07 19/90 K.AQVQLDSDHLEEDIHR.L "sp|P07197|NFM_HUMAN,tr|E7ESP9|E7ESP9_HUMAN,tr|E7EMV2|E7EMV2_HUMAN" 3 1903.9024 0.9 144624 13677 4 1903.896277 476.9829 Neurofilament medium polypeptide OS=Homo sapiens OX=9606 GN=NEFM PE=1 SV=3 4.42 2585.7 - 716010 - - - -3.2255 - 3.111 0.478 - 392.6 1 2 0 -0.0061 16 0 0 0 8.55E+06 9.50E+06 - - - 3.7846 0.9999 221125_WJC_METTL3_EV_vs_WT_F10.13680.13680.4 0.000114 11/198 K.GEGESPPVNGTDEAAGATGDAIEPAPPSQGAEAK.G sp|P49006|MRP_HUMAN 1 3176.4382 0.88 144627 13680 4 3176.446373 795.1168 MARCKS-related protein OS=Homo sapiens OX=9606 GN=MARCKSL1 PE=1 SV=2 3.71 2586.1 - 296538 - - - 2.5809 - 2.427 0.554 - 36.9 1 2 0 0.0082 34 0 0 0 8.43E+06 9.57E+06 - - - 4.3102 0.9869 221125_WJC_METTL3_EV_vs_WT_F10.13681.13681.3 0.73 Jun-36 R.K[136.11]QDSGHLDLR[166.11].N "sp|Q86U44|MTA70_HUMAN,tr|B4E349|B4E349_HUMAN,tr|F5H6D8|F5H6D8_HUMAN,tr|B4DTN4|B4DTN4_HUMAN" 4 1185.6221 0.04 144628 13681 3 1185.62059 396.2146 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 6.75 2586.2 - 146228 - - - -1.2778 - 1.38 0.201 - 58.6 1 2 0 -0.0015 10 0 0 0 2.09E+05 5.57E+06 - - - 1.7212 1 221125_WJC_METTL3_EV_vs_WT_F10.13683.13683.3 8.79E-14 29/112 R.VPSAAC[160.03]PPFPPHGAPVSASSSSSSPGGSR.G sp|Q9H7S9|ZN703_HUMAN 1 2734.2769 3.75 144629 13683 3 2734.274298 912.4329 Zinc finger protein 703 OS=Homo sapiens OX=9606 GN=ZNF703 PE=1 SV=1 8.23 2586.4 - 758469 - - - -0.9615 - 5.018 0.749 - 569 1 2 0 -0.0026 29 0 0 0 3.38E+07 8.99E+06 - - - 10.6009 0.9999 221125_WJC_METTL3_EV_vs_WT_F10.13685.13685.4 3.93E-06 20/144 R.YYEVLGAAATTDYNNNHEGR[166.11]EEDQR[166.11].L "sp|P46379|BAG6_HUMAN,tr|A0A7I2V508|A0A7I2V508_HUMAN,tr|A0A0G2JJM1|A0A0G2JJM1_HUMAN,tr|X6REW1|X6REW1_HUMAN,tr|A0A7P0MQS5|A0A7P0MQS5_HUMAN,tr|F6S6P2|F6S6P2_HUMAN,tr|A0A0G2JL47|A0A0G2JL47_HUMAN,tr|A0A024RCR6|A0A024RCR6_HUMAN,tr|A0A0G2JK23|A0A0G2JK23_HUMAN" 9 2934.2919 1.61 144630 13685 4 2934.291269 734.5803 Large proline-rich protein BAG6 OS=Homo sapiens OX=9606 GN=BAG6 PE=1 SV=2 4.35 2586.7 - 1.07E+06 - - - -0.2311 - 3.507 0.61 - 194.5 1 2 1 -0.0007 25 0 0 0 9.07E+07 5.63E+07 - - - 4.9344 0.9985 221125_WJC_METTL3_EV_vs_WT_F10.13690.13690.3 6.04E-08 15/108 P.TAPTSGGPK[136.11]PSTASAVPELATDPELEK[136.11]K[136.11].L "sp|Q86U44|MTA70_HUMAN,tr|B4E349|B4E349_HUMAN,tr|F5H6D8|F5H6D8_HUMAN,tr|H0YFV6|H0YFV6_HUMAN,tr|B4DTN4|B4DTN4_HUMAN" 5 2802.4713 0.001 144635 13690 3 2802.473946 935.1644 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 4.87 2587.3 - 242698 - - - 0.937 - 2.911 0.607 - 168.7 1 1 0 0.0026 28 0 0 0 0.00E+00 3.22E+06 - - - 7.7649 0.9967 221125_WJC_METTL3_EV_vs_WT_F10.13696.13696.4 6.34E-08 15/138 R.SQSC[160.03]GPQPSWGASC[160.03]PELRPHVEPR.P sp|Q5T749|KPRP_HUMAN 1 2718.2391 458.91 144639 13696 4 2718.244775 680.5671 Keratinocyte proline-rich protein OS=Homo sapiens OX=9606 GN=KPRP PE=1 SV=1 6.47 2588 - 789610 - - - 2.087 - 2.352 0.592 - 116.8 1 1 0 0.0057 24 0 0 0 1.26E+08 2.73E+05 - - - 4.6517 0.9937 221125_WJC_METTL3_EV_vs_WT_F10.13698.13698.4 0.0363 Nov-78 R.QRPAEIKDYSPYFK.T sp|P02533|K1C14_HUMAN 1 1740.8835 340.04 144641 13698 4 1740.886752 436.2282 "Keratin, type I cytoskeletal 14 OS=Homo sapiens OX=9606 GN=KRT14 PE=1 SV=4" 8.43 2588.3 - 312497 - - - 1.856 - 1.782 0.296 - 96.4 1 2 1 0.0032 14 0 0 0 7.20E+06 2.12E+04 - - - 2.0118 0.9997 221125_WJC_METTL3_EV_vs_WT_F10.13703.13703.4 4.47E-08 17/198 K.GEGESPPVNGTDEAAGATGDAIEPAPPSQGAEAK[136.11].G sp|P49006|MRP_HUMAN 1 3184.4524 1.18 144644 13703 4 3185.456695 797.1204 MARCKS-related protein OS=Homo sapiens OX=9606 GN=MARCKSL1 PE=1 SV=2 3.71 2588.9 - 384519 - - - 315.3823 - 2.782 0.655 - 97.6 1 2 0 1.0043 34 0 0 0 8.43E+06 7.13E+06 - - - 4.954 0.9997 221125_WJC_METTL3_EV_vs_WT_F10.13711.13711.3 4.49E-12 16/112 R.VPSAAC[160.03]PPFPPHGAPVSASSSSSSPGGSR[166.11].G sp|Q9H7S9|ZN703_HUMAN 1 2744.2852 4.81 144649 13711 3 2745.287069 915.769 Zinc finger protein 703 OS=Homo sapiens OX=9606 GN=ZNF703 PE=1 SV=1 8.23 2589.9 - 259896 - - - 365.0758 - 3.246 0.657 - 113.2 1 2 0 1.0019 29 0 0 0 5.25E+07 1.09E+07 - - - 8.2962 1 221125_WJC_METTL3_EV_vs_WT_F10.13713.13713.4 1.25E-09 18/114 R.K[136.11]QTIDNSQGAYQEAFDISK[136.11]K[136.11].E sp|P27348|1433T_HUMAN 1 2294.1605 1.65 144650 13713 4 2294.158162 574.5474 14-3-3 protein theta OS=Homo sapiens OX=9606 GN=YWHAQ PE=1 SV=1 6.12 2590.1 - 842030 - - - -1.0148 - 3.232 0.559 - 202.5 1 2 0 -0.0023 20 0 0 0 1.38E+08 8.33E+07 - - - 4.4831 0.9998 221125_WJC_METTL3_EV_vs_WT_F10.13716.13716.3 7.05E-07 Nov-76 R.KQTIDNSQGAYQEAFDISKK.E sp|P27348|1433T_HUMAN 1 2270.1179 1.21 144653 13716 3 2270.128269 757.7132 14-3-3 protein theta OS=Homo sapiens OX=9606 GN=YWHAQ PE=1 SV=1 6.12 2590.5 - 212538 - - - 4.572 - 2.79 0.609 - 92 1 2 0 0.0104 20 0 0 0 2.84E+07 2.34E+07 - - - 7.8161 0.9984 221125_WJC_METTL3_EV_vs_WT_F10.13722.13722.3 8.57E-09 17/76 R.K[136.11]QTIDNSQGAYQEAFDISK[136.11]K[136.11].E sp|P27348|1433T_HUMAN 1 2294.1605 1.21 144657 13722 3 2295.160152 765.7274 14-3-3 protein theta OS=Homo sapiens OX=9606 GN=YWHAQ PE=1 SV=1 6.12 2591.3 - 403561 - - - 435.742 - 3.028 0.469 - 346.7 1 2 0 0.9997 20 0 0 0 2.84E+07 2.34E+07 - - - 6.1798 0.9993 221125_WJC_METTL3_EV_vs_WT_F10.13724.13724.2 0.00032 22-Aug K.NAGVEGSLIVEK[136.11].L "sp|P10809|CH60_HUMAN,tr|A0A7I2V2X6|A0A7I2V2X6_HUMAN,tr|A0A7I2YQK6|A0A7I2YQK6_HUMAN,tr|A0A7I2V599|A0A7I2V599_HUMAN" 4 1222.6649 1.33 144659 13724 2 1222.667693 612.3397 "60 kDa heat shock protein, mitochondrial OS=Homo sapiens OX=9606 GN=HSPD1 PE=1 SV=2" 4.53 2591.6 - 247254 - - - 2.3113 - 1.73 0.443 - 171.9 1 2 0 0.0028 12 0 0 0 5.63E+06 4.24E+06 - - - 3.7543 0.9881 221125_WJC_METTL3_EV_vs_WT_F10.13725.13725.3 0.19 Jun-64 R.KSANNTPENSPNFPNFR.V sp|Q9NRL2|BAZ1A_HUMAN 1 1932.9078 0.87 144660 13725 3 1932.904628 645.3099 Bromodomain adjacent to zinc finger domain protein 1A OS=Homo sapiens OX=9606 GN=BAZ1A PE=1 SV=2 8.75 2591.7 - 171298 - - - -1.6607 - 1.556 0.203 - 38.6 1 2 0 -0.0032 17 0 0 0 3.43E+06 3.94E+06 - - - 1.9193 0.9997 221125_WJC_METTL3_EV_vs_WT_F10.13727.13727.4 0.00333 Aug-84 R.VLSAPPHFHFGQTNR.T sp|P26641|EF1G_HUMAN 1 1706.8641 1.12 144662 13727 4 1706.865235 427.7233 Elongation factor 1-gamma OS=Homo sapiens OX=9606 GN=EEF1G PE=1 SV=3 9.73 2592 - 93702 - - - 0.6515 - 1.728 0.363 - 25.6 1 2 0 0.0011 15 0 0 0 3.48E+06 3.11E+06 - - - 2.581 0.9999 221125_WJC_METTL3_EV_vs_WT_F10.13731.13731.4 4.36E-08 18/144 K.LTDTSKDEENHEESESLQEDMLGNR.L "sp|Q8IX12|CCAR1_HUMAN,tr|A0A0C4DGG8|A0A0C4DGG8_HUMAN" 2 2905.252 6.03 144664 13731 4 2905.246742 727.3203 Cell division cycle and apoptosis regulator protein 1 OS=Homo sapiens OX=9606 GN=CCAR1 PE=1 SV=2 4.05 2592.4 - 629492 - - - -1.794 - 2.831 0.612 - 202.5 1 2 1 -0.0052 25 0 0 0 1.19E+07 1.97E+06 - - - 4.8825 0.9999 221125_WJC_METTL3_EV_vs_WT_F10.13739.13739.4 0.000245 Aug-84 R.VLSAPPHFHFGQTNR[166.11].T sp|P26641|EF1G_HUMAN 1 1716.8724 1.15 144669 13739 4 1716.87178 430.2254 Elongation factor 1-gamma OS=Homo sapiens OX=9606 GN=EEF1G PE=1 SV=3 9.73 2593.5 - 152373 - - - -0.357 - 1.708 0.418 - 37.1 1 2 0 -0.0006 15 0 0 0 4.00E+06 3.49E+06 - - - 3.0556 0.9987 221125_WJC_METTL3_EV_vs_WT_F10.13741.13741.3 2.10E-12 16/92 R.SQSC[160.03]GPQPSWGASC[160.03]PELRPHVEPR.P sp|Q5T749|KPRP_HUMAN 1 2718.2391 107.17 144671 13741 3 2718.242484 907.087 Keratinocyte proline-rich protein OS=Homo sapiens OX=9606 GN=KPRP PE=1 SV=1 6.47 2593.8 - 325746 - - - 1.2442 - 2.812 0.654 - 154.5 1 1 0 0.0034 24 0 0 0 1.25E+07 1.17E+05 - - - 8.2318 1 221125_WJC_METTL3_EV_vs_WT_F10.13744.13744.3 2.90E-09 14/88 R.NSESESNK[136.11]VAAETQSPSLFGSTK[136.11].L sp|Q9UKX7|NUP50_HUMAN 1 2413.158 1.42 144672 13744 3 2413.155734 805.3933 Nuclear pore complex protein Nup50 OS=Homo sapiens OX=9606 GN=NUP50 PE=1 SV=2 4.79 2594.2 - 345884 - - - -0.9295 - 3.374 0.659 - 176.8 1 2 1 -0.0022 23 0 0 0 4.07E+07 2.86E+07 - - - 8.7395 1 221125_WJC_METTL3_EV_vs_WT_F10.13746.13746.3 2.45E-13 21/88 R.NSESESNKVAAETQSPSLFGSTK.L sp|Q9UKX7|NUP50_HUMAN 1 2397.1296 1.42 144674 13746 3 2397.12402 800.0505 Nuclear pore complex protein Nup50 OS=Homo sapiens OX=9606 GN=NUP50 PE=1 SV=2 4.79 2594.4 - 487322 - - - -2.3182 - 4.227 0.753 - 391.9 1 2 1 -0.0056 23 0 0 0 4.07E+07 2.86E+07 - - - 10.3153 1 221125_WJC_METTL3_EV_vs_WT_F10.13753.13753.4 1.24E-07 27/198 K.GPPAATATSAAAAAAATGAPATSSSDSGGGGGC[160.03]R.E "sp|P31270|HXA11_HUMAN,tr|H0YIA6|H0YIA6_HUMAN" 2 2831.274 1.46 144679 13753 4 2831.272083 708.8258 Homeobox protein Hox-A11 OS=Homo sapiens OX=9606 GN=HOXA11 PE=2 SV=2 5.83 2595.3 - 424124 - - - -0.6866 - 4.381 0.658 - 326.2 1 2 0 -0.0019 34 0 0 0 1.10E+07 7.54E+06 - - - 5.3932 1 221125_WJC_METTL3_EV_vs_WT_F10.13754.13754.3 5.39E-11 24/116 R.GTEAGQVGEPGIPTGEAGPSC[160.03]SSASDK[136.11]LPR[166.11].V sp|O15355|PPM1G_HUMAN 1 2929.3842 0.71 144680 13754 3 2929.38039 977.4687 Protein phosphatase 1G OS=Homo sapiens OX=9606 GN=PPM1G PE=1 SV=1 4.41 2595.5 - 454563 - - - -1.3173 - 4.338 0.644 - 333 1 2 1 -0.0039 30 0 0 0 2.00E+07 2.80E+07 - - - 9.0949 0.9998 221125_WJC_METTL3_EV_vs_WT_F10.13755.13755.4 1.87E-07 19/102 K.KQQEQLQLQLLQQQHAGK.Q "sp|Q9H334|FOXP1_HUMAN,tr|C9J5T4|C9J5T4_HUMAN,tr|A0A3B3IRW5|A0A3B3IRW5_HUMAN,tr|G5E965|G5E965_HUMAN,tr|A0A3B3IRS5|A0A3B3IRS5_HUMAN,tr|A0A3B3IST0|A0A3B3IST0_HUMAN,tr|A0A3B3IT14|A0A3B3IT14_HUMAN,tr|A0A3B3ISA4|A0A3B3ISA4_HUMAN,tr|C9J0F0|C9J0F0_HUMAN,tr|A0A3B3IU15|A0A3B3IU15_HUMAN,tr|A0A3B3IUB6|A0A3B3IUB6_HUMAN,tr|A0A3B3IT66|A0A3B3IT66_HUMAN,tr|A0A087X2G3|A0A087X2G3_HUMAN,tr|A0A0B4J2F3|A0A0B4J2F3_HUMAN,tr|A0A3B3IU08|A0A3B3IU08_HUMAN,tr|A0A3B3IST6|A0A3B3IST6_HUMAN,tr|C9IYY1|C9IYY1_HUMAN,tr|A0A3B3IT26|A0A3B3IT26_HUMAN" 18 2145.1654 3.78 144681 13755 4 2145.172894 537.2986 Forkhead box protein P1 OS=Homo sapiens OX=9606 GN=FOXP1 PE=1 SV=1 8.6 2595.6 - 239931 - - - 3.4701 - 3.41 0.471 - 341.4 1 2 0 0.0074 18 0 0 0 2.09E+07 5.53E+06 - - - 3.7437 0.9136 221125_WJC_METTL3_EV_vs_WT_F10.13756.13756.3 0.795 Feb-80 R.GSWTSC[160.03]SSSSHDNFQSLPNPK[136.11].S "sp|Q8TEU7|RPGF6_HUMAN,tr|E9PCH4|E9PCH4_HUMAN,tr|A0A5F9ZHG7|A0A5F9ZHG7_HUMAN" 3 2330.0113 0.1 144682 13756 3 2330.010728 777.6777 Rap guanine nucleotide exchange factor 6 OS=Homo sapiens OX=9606 GN=RAPGEF6 PE=1 SV=2 6.73 2595.7 - 233491 - - - -0.2558 - 0.837 0.279 - 4.7 31 2 0 -0.0006 21 0 0 0 3.07E+05 3.19E+06 - - - 0.5336 0.8057 221125_WJC_METTL3_EV_vs_WT_F10.13758.13758.2 21.5 12-Apr K.FIEIAAR[166.11].K "sp|Q00839|HNRPU_HUMAN,tr|A0A1W2PQL0|A0A1W2PQL0_HUMAN,tr|A0A1W2PPE9|A0A1W2PPE9_HUMAN,tr|A0A1W2PPL4|A0A1W2PPL4_HUMAN,tr|A0A1W2PQ74|A0A1W2PQ74_HUMAN,tr|Q5RI18|Q5RI18_HUMAN,tr|A0A1W2PP35|A0A1W2PP35_HUMAN,tr|A0A1W2PPS1|A0A1W2PPS1_HUMAN,tr|A0A1W2PRZ7|A0A1W2PRZ7_HUMAN,tr|A0A1W2PPH7|A0A1W2PPH7_HUMAN,tr|A0A1W2PQD4|A0A1W2PQD4_HUMAN,tr|A0A1W2PP34|A0A1W2PP34_HUMAN,tr|A0A1X7SBS1|A0A1X7SBS1_HUMAN" 13 828.4733 1.05 144684 13758 2 828.472427 415.2439 Heterogeneous nuclear ribonucleoprotein U OS=Homo sapiens OX=9606 GN=HNRNPU PE=1 SV=6 6 2596 - 112744 - - - -1.0634 - 0.977 0 - 67.1 3 2 0 -0.0009 7 0 0 0 3.18E+06 3.02E+06 - - - -1.2461 1 221125_WJC_METTL3_EV_vs_WT_F10.13763.13763.3 7.86E-13 23/116 R.GTEAGQVGEPGIPTGEAGPSC[160.03]SSASDKLPR.V sp|O15355|PPM1G_HUMAN 1 2911.3618 0.71 144687 13763 3 2911.364217 971.4612 Protein phosphatase 1G OS=Homo sapiens OX=9606 GN=PPM1G PE=1 SV=1 4.41 2596.7 - 524523 - - - 0.8374 - 4.284 0.669 - 318.4 1 2 1 0.0024 30 0 0 0 2.00E+07 2.80E+07 - - - 9.3452 0.9935 221125_WJC_METTL3_EV_vs_WT_F10.13766.13766.4 0.0245 13/144 R.FNSHESAAHAIVSVNGTTIEGHVVK.C "sp|P31483|TIA1_HUMAN,tr|F8W8I6|F8W8I6_HUMAN,tr|F8WE16|F8WE16_HUMAN" 3 2603.3092 2.49 144690 13766 4 2603.309069 651.8346 Nucleolysin TIA-1 isoform p40 OS=Homo sapiens OX=9606 GN=TIA1 PE=1 SV=3 6.27 2597 - 159571 - - - -0.0557 - 1.913 0.217 - 61.4 1 2 0 -0.0001 25 0 0 0 5.83E+06 2.34E+06 - - - 1.3211 0.9983 221125_WJC_METTL3_EV_vs_WT_F10.13773.13773.2 0.262 14-Aug K.IEISELNR.V "sp|P04264|K2C1_HUMAN,sp|P35908|K22E_HUMAN" 2 972.524 47.23 144695 13773 2 972.524215 487.2693 "Keratin, type II cytoskeletal 1 OS=Homo sapiens OX=9606 GN=KRT1 PE=1 SV=6" 4.53 2597.9 - 432165 - - - 0.2108 - 1.769 0.16 - 223.9 1 2 0 0.0002 8 0 0 0 1.90E+07 4.03E+05 - - - 1.943 1 221125_WJC_METTL3_EV_vs_WT_F10.13774.13774.3 1.35E-17 27/132 K.GPPAATATSAAAAAAATGAPATSSSDSGGGGGC[160.03]R.E "sp|P31270|HXA11_HUMAN,tr|H0YIA6|H0YIA6_HUMAN" 2 2831.274 10.53 144696 13774 3 2831.276015 944.7653 Homeobox protein Hox-A11 OS=Homo sapiens OX=9606 GN=HOXA11 PE=2 SV=2 5.83 2598 - 323521 - - - 0.7022 - 4.778 0.787 - 498.9 1 2 0 0.002 34 0 0 0 5.06E+06 4.80E+05 - - - 10.912 1 221125_WJC_METTL3_EV_vs_WT_F10.13776.13776.3 0.00984 18/56 R.STSHK[136.11]PDEIYGMIER[166.11].L sp|Q86U44|MTA70_HUMAN 1 1779.8581 0.01 144697 13776 3 1779.856982 594.2933 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 5.42 2598.2 - 1.17E+06 - - - -0.6023 - 3.098 0.452 - 402.3 1 2 0 -0.0011 15 0 0 0 4.69E+05 5.55E+07 - - - 6.5296 1 221125_WJC_METTL3_EV_vs_WT_F10.13778.13778.4 1.68E-05 15/84 R.STSHK[136.11]PDEIYGMIER[166.11].L sp|Q86U44|MTA70_HUMAN 1 1779.8581 0.06 144698 13778 4 1779.858874 445.9718 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 5.42 2598.4 - 779700 - - - 0.4607 - 2.438 0.508 - 127.8 1 2 0 0.0008 15 0 0 0 1.81E+06 3.06E+07 - - - 3.9663 0.9987 221125_WJC_METTL3_EV_vs_WT_F10.13783.13783.3 0.0465 Jun-40 K.IWHHTFYNELR[166.11].V "sp|Q6S8J3|POTEE_HUMAN,sp|P63261|ACTG_HUMAN,sp|P68133|ACTS_HUMAN,sp|Q9BYX7|ACTBM_HUMAN,sp|P68032|ACTC_HUMAN,sp|P60709|ACTB_HUMAN,sp|A5A3E0|POTEF_HUMAN,sp|P0CG38|POTEI_HUMAN,sp|P0CG39|POTEJ_HUMAN,tr|A0A804GS07|A0A804GS07_HUMAN,tr|I3L3I0|I3L3I0_HUMAN,tr|G5E9R0|G5E9R0_HUMAN,tr|E7EVS6|E7EVS6_HUMAN,tr|A0A6Q8PFE4|A0A6Q8PFE4_HUMAN,tr|J3KT65|J3KT65_HUMAN,tr|I3L3R2|I3L3R2_HUMAN,tr|K7EM38|K7EM38_HUMAN,tr|A0A6Q8PH58|A0A6Q8PH58_HUMAN,tr|I3L1U9|I3L1U9_HUMAN,tr|A0A804HKV3|A0A804HKV3_HUMAN,tr|A0A2R8Y793|A0A2R8Y793_HUMAN,tr|I3L4N8|I3L4N8_HUMAN,tr|C9JUM1|C9JUM1_HUMAN,tr|C9JZR7|C9JZR7_HUMAN,tr|A0A2R8YGF8|A0A2R8YGF8_HUMAN,tr|A6NL76|A6NL76_HUMAN" 26 1524.7502 0.91 144701 13783 3 1524.750976 509.2573 POTE ankyrin domain family member E OS=Homo sapiens OX=9606 GN=POTEE PE=2 SV=3 6.92 2599.1 - 94436.7 - - - 0.5404 - 1.144 0.378 - 36.8 1 2 0 0.0008 11 0 0 0 1.06E+07 1.17E+07 - - - 3.1363 0.9999 221125_WJC_METTL3_EV_vs_WT_F10.13792.13792.4 1.55E-05 12/102 K.K[136.11]QQEQLQLQLLQQQHAGK[136.11].Q "sp|Q9H334|FOXP1_HUMAN,tr|C9J5T4|C9J5T4_HUMAN,tr|A0A3B3IRW5|A0A3B3IRW5_HUMAN,tr|G5E965|G5E965_HUMAN,tr|A0A3B3IRS5|A0A3B3IRS5_HUMAN,tr|A0A3B3IST0|A0A3B3IST0_HUMAN,tr|A0A3B3IT14|A0A3B3IT14_HUMAN,tr|A0A3B3ISA4|A0A3B3ISA4_HUMAN,tr|C9J0F0|C9J0F0_HUMAN,tr|A0A3B3IU15|A0A3B3IU15_HUMAN,tr|A0A3B3IUB6|A0A3B3IUB6_HUMAN,tr|A0A3B3IT66|A0A3B3IT66_HUMAN,tr|A0A087X2G3|A0A087X2G3_HUMAN,tr|A0A0B4J2F3|A0A0B4J2F3_HUMAN,tr|A0A3B3IU08|A0A3B3IU08_HUMAN,tr|A0A3B3IST6|A0A3B3IST6_HUMAN,tr|C9IYY1|C9IYY1_HUMAN,tr|A0A3B3IT26|A0A3B3IT26_HUMAN" 18 2161.1939 3.83 144706 13792 4 2161.194417 541.3057 Forkhead box protein P1 OS=Homo sapiens OX=9606 GN=FOXP1 PE=1 SV=1 8.6 2600.2 - 182422 - - - 0.2624 - 2.499 0.43 - 102.9 1 2 0 0.0006 18 0 0 0 2.09E+07 5.46E+06 - - - 3.2823 1 221125_WJC_METTL3_EV_vs_WT_F10.13801.13801.3 5.39E-05 Nov-40 K.IWHHTFYNELR.V "sp|Q6S8J3|POTEE_HUMAN,sp|P63261|ACTG_HUMAN,sp|P68133|ACTS_HUMAN,sp|Q9BYX7|ACTBM_HUMAN,sp|P68032|ACTC_HUMAN,sp|P60709|ACTB_HUMAN,sp|A5A3E0|POTEF_HUMAN,sp|P0CG38|POTEI_HUMAN,sp|P0CG39|POTEJ_HUMAN,tr|A0A804GS07|A0A804GS07_HUMAN,tr|I3L3I0|I3L3I0_HUMAN,tr|G5E9R0|G5E9R0_HUMAN,tr|E7EVS6|E7EVS6_HUMAN,tr|A0A6Q8PFE4|A0A6Q8PFE4_HUMAN,tr|J3KT65|J3KT65_HUMAN,tr|I3L3R2|I3L3R2_HUMAN,tr|K7EM38|K7EM38_HUMAN,tr|A0A6Q8PH58|A0A6Q8PH58_HUMAN,tr|I3L1U9|I3L1U9_HUMAN,tr|A0A804HKV3|A0A804HKV3_HUMAN,tr|A0A2R8Y793|A0A2R8Y793_HUMAN,tr|I3L4N8|I3L4N8_HUMAN,tr|C9JUM1|C9JUM1_HUMAN,tr|C9JZR7|C9JZR7_HUMAN,tr|A0A2R8YGF8|A0A2R8YGF8_HUMAN,tr|A6NL76|A6NL76_HUMAN" 26 1514.7419 0.91 144711 13801 3 1514.742547 505.9212 POTE ankyrin domain family member E OS=Homo sapiens OX=9606 GN=POTEE PE=2 SV=3 6.92 2601.4 - 340406 - - - 0.439 - 2.226 0.512 - 215.7 1 2 0 0.0007 11 0 0 0 1.06E+07 1.17E+07 - - - 6.5214 0.8748 221125_WJC_METTL3_EV_vs_WT_F10.13806.13806.4 1.72 May-60 K.IWHHTFYNELR[166.11].V "sp|Q6S8J3|POTEE_HUMAN,sp|P63261|ACTG_HUMAN,sp|P68133|ACTS_HUMAN,sp|Q9BYX7|ACTBM_HUMAN,sp|P68032|ACTC_HUMAN,sp|P60709|ACTB_HUMAN,sp|A5A3E0|POTEF_HUMAN,sp|P0CG38|POTEI_HUMAN,sp|P0CG39|POTEJ_HUMAN,tr|A0A804GS07|A0A804GS07_HUMAN,tr|I3L3I0|I3L3I0_HUMAN,tr|G5E9R0|G5E9R0_HUMAN,tr|E7EVS6|E7EVS6_HUMAN,tr|A0A6Q8PFE4|A0A6Q8PFE4_HUMAN,tr|J3KT65|J3KT65_HUMAN,tr|I3L3R2|I3L3R2_HUMAN,tr|K7EM38|K7EM38_HUMAN,tr|A0A6Q8PH58|A0A6Q8PH58_HUMAN,tr|I3L1U9|I3L1U9_HUMAN,tr|A0A804HKV3|A0A804HKV3_HUMAN,tr|A0A2R8Y793|A0A2R8Y793_HUMAN,tr|I3L4N8|I3L4N8_HUMAN,tr|C9JUM1|C9JUM1_HUMAN,tr|C9JZR7|C9JZR7_HUMAN,tr|A0A2R8YGF8|A0A2R8YGF8_HUMAN,tr|A6NL76|A6NL76_HUMAN" 26 1524.7502 0.01 144714 13806 4 1524.751179 382.1948 POTE ankyrin domain family member E OS=Homo sapiens OX=9606 GN=POTEE PE=2 SV=3 6.92 2602.1 - 203325 - - - 0.6736 - 1.057 0.122 - 14.5 1 2 0 0.001 11 0 0 0 1.67E+04 2.58E+06 - - - 0.3091 0.9521 221125_WJC_METTL3_EV_vs_WT_F10.13807.13807.4 0.646 Apr-90 R.FHMDSETHDPIDLQTK.E "sp|Q9Y2L1|RRP44_HUMAN,tr|G3V1J5|G3V1J5_HUMAN" 2 1912.8625 1.63 144715 13807 4 1912.86575 479.2229 Exosome complex exonuclease RRP44 OS=Homo sapiens OX=9606 GN=DIS3 PE=1 SV=2 4.64 2602.2 - 57846.8 - - - 1.6849 - 1.005 0.213 - 12.3 3 2 0 0.0032 16 0 0 0 2.14E+06 1.31E+06 - - - 0.7172 0.9997 221125_WJC_METTL3_EV_vs_WT_F10.13810.13810.2 0.00115 20-Sep K.IGGIGTVPVGR.V "sp|Q05639|EF1A2_HUMAN,sp|P68104|EF1A1_HUMAN,sp|Q5VTE0|EF1A3_HUMAN,tr|A0A7I2V659|A0A7I2V659_HUMAN,tr|A0A7I2V3H3|A0A7I2V3H3_HUMAN,tr|A0A2U3TZH3|A0A2U3TZH3_HUMAN,tr|A0A7I2V5N4|A0A7I2V5N4_HUMAN,tr|A0A087WVQ9|A0A087WVQ9_HUMAN" 8 1024.6029 9.82 144716 13810 2 1024.60404 513.3087 Elongation factor 1-alpha 2 OS=Homo sapiens OX=9606 GN=EEF1A2 PE=1 SV=1 9.75 2602.6 - 312491 - - - 1.0843 - 2.209 0.376 - 199.4 1 2 0 0.0011 11 0 0 0 3.14E+07 3.19E+06 - - - 3.9618 0.9998 221125_WJC_METTL3_EV_vs_WT_F10.13816.13816.4 4.98E-05 14/120 K.FKDPNC[160.03]VGTVLASRPHTLDGR.N "sp|Q96EP5|DAZP1_HUMAN,tr|K7EK33|K7EK33_HUMAN,tr|K7EQ55|K7EQ55_HUMAN,tr|K7EQ02|K7EQ02_HUMAN" 4 2339.1804 1.37 144720 13816 4 2339.184598 585.8024 DAZ-associated protein 1 OS=Homo sapiens OX=9606 GN=DAZAP1 PE=1 SV=1 8.23 2603.4 - 362084 - - - 1.7741 - 2.839 0.49 - 124 1 2 1 0.0042 21 0 0 0 4.74E+07 3.46E+07 - - - 3.8348 1 221125_WJC_METTL3_EV_vs_WT_F10.13818.13818.3 6.29E-14 20/100 K.VSGGSTHGTWGSLQETC[160.03]ESEVSGTQK.V sp|Q8NDV7|TNR6A_HUMAN 1 2708.1984 1.45 144722 13818 3 2708.198495 903.7401 Trinucleotide repeat-containing gene 6A protein OS=Homo sapiens OX=9606 GN=TNRC6A PE=1 SV=2 4.75 2603.7 - 437480 - - - 0.0343 - 3.83 0.66 - 383.8 1 2 0 0.0001 26 0 0 0 9.34E+06 6.46E+06 - - - 8.9878 1 221125_WJC_METTL3_EV_vs_WT_F10.13819.13819.4 4.45E-07 20/120 R.C[160.03]HDGTIEFTSIDAHNGVAPSR.R "sp|Q99986|VRK1_HUMAN,tr|A0A7P0T838|A0A7P0T838_HUMAN,tr|H0YJJ9|H0YJJ9_HUMAN,tr|A0A7P0TA16|A0A7P0TA16_HUMAN,tr|A0A7P0T8N0|A0A7P0T8N0_HUMAN,tr|H0YJF7|H0YJF7_HUMAN,tr|A0A7P0T9T1|A0A7P0T9T1_HUMAN,tr|A0A7P0Z4A4|A0A7P0Z4A4_HUMAN,tr|A0A7P0Z445|A0A7P0Z445_HUMAN,tr|A0A7P0TAA6|A0A7P0TAA6_HUMAN,tr|A0A7P0T9E5|A0A7P0T9E5_HUMAN,tr|A0A7P0TBB8|A0A7P0TBB8_HUMAN,tr|A0A7P0Z462|A0A7P0Z462_HUMAN,tr|A0A7P0TBE4|A0A7P0TBE4_HUMAN,tr|A0A7P0T925|A0A7P0T925_HUMAN,tr|H0YJ50|H0YJ50_HUMAN,tr|A0A7P0TA65|A0A7P0TA65_HUMAN,tr|A0A7P0T824|A0A7P0T824_HUMAN,tr|A0A7P0T9I1|A0A7P0T9I1_HUMAN,tr|A0A7P0T977|A0A7P0T977_HUMAN,tr|A0A7P0Z3Z7|A0A7P0Z3Z7_HUMAN,tr|A0A7P0TAS8|A0A7P0TAS8_HUMAN,tr|A0A7P0T9C6|A0A7P0T9C6_HUMAN,tr|A0A7P0TBI6|A0A7P0TBI6_HUMAN,tr|A0A7P0T952|A0A7P0T952_HUMAN" 25 2283.0338 0.42 144723 13819 4 2283.034091 571.7657 Serine\threonine-protein kinase VRK1 OS=Homo sapiens OX=9606 GN=VRK1 PE=1 SV=1 5.21 2603.8 - 282713 - - - 0.1086 - 4.053 0.657 - 448 1 2 0 0.0002 21 0 0 0 5.78E+06 1.37E+07 - - - 5.4072 1 221125_WJC_METTL3_EV_vs_WT_F10.13836.13836.4 6.18E-11 19/120 R.C[160.03]HDGTIEFTSIDAHNGVAPSR[166.11].R "sp|Q99986|VRK1_HUMAN,tr|A0A7P0T838|A0A7P0T838_HUMAN,tr|H0YJJ9|H0YJJ9_HUMAN,tr|A0A7P0TA16|A0A7P0TA16_HUMAN,tr|A0A7P0T8N0|A0A7P0T8N0_HUMAN,tr|H0YJF7|H0YJF7_HUMAN,tr|A0A7P0T9T1|A0A7P0T9T1_HUMAN,tr|A0A7P0Z4A4|A0A7P0Z4A4_HUMAN,tr|A0A7P0Z445|A0A7P0Z445_HUMAN,tr|A0A7P0TAA6|A0A7P0TAA6_HUMAN,tr|A0A7P0T9E5|A0A7P0T9E5_HUMAN,tr|A0A7P0TBB8|A0A7P0TBB8_HUMAN,tr|A0A7P0Z462|A0A7P0Z462_HUMAN,tr|A0A7P0TBE4|A0A7P0TBE4_HUMAN,tr|A0A7P0T925|A0A7P0T925_HUMAN,tr|H0YJ50|H0YJ50_HUMAN,tr|A0A7P0TA65|A0A7P0TA65_HUMAN,tr|A0A7P0T824|A0A7P0T824_HUMAN,tr|A0A7P0T9I1|A0A7P0T9I1_HUMAN,tr|A0A7P0T977|A0A7P0T977_HUMAN,tr|A0A7P0Z3Z7|A0A7P0Z3Z7_HUMAN,tr|A0A7P0TAS8|A0A7P0TAS8_HUMAN,tr|A0A7P0T9C6|A0A7P0T9C6_HUMAN,tr|A0A7P0TBI6|A0A7P0TBI6_HUMAN,tr|A0A7P0T952|A0A7P0T952_HUMAN" 25 2293.0421 0.41 144733 13836 4 2293.047557 574.2678 Serine\threonine-protein kinase VRK1 OS=Homo sapiens OX=9606 GN=VRK1 PE=1 SV=1 5.21 2606.2 - 452656 - - - 2.3741 - 3.98 0.67 - 407.6 1 2 0 0.0054 21 0 0 0 5.78E+06 1.39E+07 - - - 5.5129 1 221125_WJC_METTL3_EV_vs_WT_F10.13844.13844.4 5.44E-13 27/120 K.FK[136.11]DPNC[160.03]VGTVLASR[166.11]PHTLDGR[166.11].N "sp|Q96EP5|DAZP1_HUMAN,tr|K7EK33|K7EK33_HUMAN,tr|K7EQ55|K7EQ55_HUMAN,tr|K7EQ02|K7EQ02_HUMAN" 4 2367.2112 1.37 144738 13844 4 2367.219928 592.8101 DAZ-associated protein 1 OS=Homo sapiens OX=9606 GN=DAZAP1 PE=1 SV=1 8.23 2607.2 - 1.78E+06 - - - 3.6921 - 4.11 0.632 - 433.6 1 2 1 0.0087 21 0 0 0 4.74E+07 3.47E+07 - - - 5.1918 1 221125_WJC_METTL3_EV_vs_WT_F10.13845.13845.4 2.78E-08 15/84 K.THINIVVIGHVDSGK[136.11].S "sp|Q05639|EF1A2_HUMAN,sp|P68104|EF1A1_HUMAN,sp|Q5VTE0|EF1A3_HUMAN,tr|A0A2R8Y488|A0A2R8Y488_HUMAN,tr|A0A2R8YDN5|A0A2R8YDN5_HUMAN,tr|A0A7I2V659|A0A7I2V659_HUMAN,tr|A0A7I2V3H3|A0A7I2V3H3_HUMAN,tr|Q5JR01|Q5JR01_HUMAN,tr|A0A2U3TZH3|A0A2U3TZH3_HUMAN,tr|A0A7I2V5N4|A0A7I2V5N4_HUMAN,tr|A0A087WVQ9|A0A087WVQ9_HUMAN,tr|A6PW80|A6PW80_HUMAN,tr|A0A087WV01|A0A087WV01_HUMAN,tr|A0A2R8Y660|A0A2R8Y660_HUMAN,tr|A0A6Q8PFK6|A0A6Q8PFK6_HUMAN" 15 1595.8875 0.37 144739 13845 4 1595.891394 399.9791 Elongation factor 1-alpha 2 OS=Homo sapiens OX=9606 GN=EEF1A2 PE=1 SV=1 6.61 2607.4 - 151884 - - - 2.4463 - 2.886 0.56 - 211.8 1 2 0 0.0039 15 0 0 0 2.43E+06 6.50E+06 - - - 4.4784 1 221125_WJC_METTL3_EV_vs_WT_F10.13848.13848.3 8.54E-09 12/100 K.VSGGSTHGTWGSLQETC[160.03]ESEVSGTQK[136.11].V sp|Q8NDV7|TNR6A_HUMAN 1 2716.2126 1.45 144742 13848 3 2716.217003 906.4115 Trinucleotide repeat-containing gene 6A protein OS=Homo sapiens OX=9606 GN=TNRC6A PE=1 SV=2 4.75 2607.8 - 169865 - - - 1.6203 - 2.795 0.665 - 135.8 1 2 0 0.0044 26 0 0 0 9.34E+06 6.46E+06 - - - 8.3175 0.9992 221125_WJC_METTL3_EV_vs_WT_F10.13850.13850.4 9.28E-05 8/132 R.SK[136.11]EVINR[166.11]PFTNESLQPHALGPVK[136.11].L "sp|Q14807|KIF22_HUMAN,tr|H3BRB3|H3BRB3_HUMAN" 2 2586.4128 1.85 144744 13850 4 2586.418695 647.6105 Kinesin-like protein KIF22 OS=Homo sapiens OX=9606 GN=KIF22 PE=1 SV=5 8.33 2608 - 122927 - - - 2.2634 - 1.813 0.432 - 37.1 1 2 1 0.0059 23 0 0 0 2.71E+06 1.46E+06 - - - 3.1773 0.9976 221125_WJC_METTL3_EV_vs_WT_F10.13852.13852.4 0.00751 17/114 K.R[166.11]GLLQDDAHPTLVTYADHSK[136.11].L "sp|Q86U44|MTA70_HUMAN,tr|F5H6D8|F5H6D8_HUMAN,tr|H0YFV6|H0YFV6_HUMAN,tr|B4DTN4|B4DTN4_HUMAN" 4 2254.1461 0.01 144745 13852 4 2254.155368 564.5438 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 5.99 2608.3 - 5.90E+06 - - - 4.1049 - 2.548 0.345 - 236.1 1 2 0 0.0093 20 0 0 0 1.57E+07 1.46E+09 - - - 2.539 1 221125_WJC_METTL3_EV_vs_WT_F10.13856.13856.3 2.12E-11 18/92 R.DGEDQTQDTELVETRPAGDGTFQK.W "sp|P04439|HLAA_HUMAN,sp|P01893|HLAH_HUMAN,sp|P10321|HLAC_HUMAN,tr|A0A1W2PP77|A0A1W2PP77_HUMAN,tr|A0A140T941|A0A140T941_HUMAN,tr|A0A1W2PQS8|A0A1W2PQS8_HUMAN,tr|A0A140T921|A0A140T921_HUMAN,tr|A0A1W2PNZ7|A0A1W2PNZ7_HUMAN,tr|A0A0G2JI36|A0A0G2JI36_HUMAN,tr|A0A140T8W8|A0A140T8W8_HUMAN,tr|Q9GJ45|Q9GJ45_HUMAN,tr|O19617|O19617_HUMAN,tr|Q53Z42|Q53Z42_HUMAN,tr|Q5RJ27|Q5RJ27_HUMAN,tr|Q53YP1|Q53YP1_HUMAN,tr|Q5RIP0|Q5RIP0_HUMAN,tr|Q5SRN5|Q5SRN5_HUMAN,tr|A0A1W2PS24|A0A1W2PS24_HUMAN,tr|A0A0G2JIF2|A0A0G2JIF2_HUMAN,tr|A0A1W2PQD0|A0A1W2PQD0_HUMAN,tr|A0A1W2PRZ0|A0A1W2PRZ0_HUMAN,tr|A0A0G2JH50|A0A0G2JH50_HUMAN,tr|A0A140T9U0|A0A140T9U0_HUMAN,tr|A0A140T955|A0A140T955_HUMAN,tr|A0A0G2JPD3|A0A0G2JPD3_HUMAN,tr|A0A140T9W2|A0A140T9W2_HUMAN,tr|O78179|O78179_HUMAN,tr|A0A140T913|A0A140T913_HUMAN,tr|A2AEA2|A2AEA2_HUMAN,tr|A0A1W2PPQ2|A0A1W2PPQ2_HUMAN,tr|Q5SPM2|Q5SPM2_HUMAN,tr|Q5SUL5|Q5SUL5_HUMAN,tr|A0A140T8Y4|A0A140T8Y4_HUMAN,tr|A0A140T975|A0A140T975_HUMAN,tr|A2BF26|A2BF26_HUMAN,tr|A0A140T933|A0A140T933_HUMAN,tr|A0A140T9H5|A0A140T9H5_HUMAN,tr|A0A1W2PS56|A0A1W2PS56_HUMAN,tr|A0A0G2JIF0|A0A0G2JIF0_HUMAN,tr|A0A1W2PSE7|A0A1W2PSE7_HUMAN,tr|Q5QT33|Q5QT33_HUMAN,tr|A0A140T9J9|A0A140T9J9_HUMAN,tr|A0A1W2PRT9|A0A1W2PRT9_HUMAN,tr|A0A140T9B3|A0A140T9B3_HUMAN,tr|A0A1W2PPF8|A0A1W2PPF8_HUMAN,tr|A0A1W2PRX1|A0A1W2PRX1_HUMAN,tr|A0A140T937|A0A140T937_HUMAN,tr|Q5SRN7|Q5SRN7_HUMAN,tr|A0A1W2PR61|A0A1W2PR61_HUMAN,tr|A0A140T912|A0A140T912_HUMAN,tr|A0A140T962|A0A140T962_HUMAN,tr|A0A140T9M0|A0A140T9M0_HUMAN,tr|A0A140T9I0|A0A140T9I0_HUMAN,tr|A0A140T9U8|A0A140T9U8_HUMAN,tr|A0A140T9X5|A0A140T9X5_HUMAN,tr|A0A1W2PS39|A0A1W2PS39_HUMAN,tr|A0A140T9Z6|A0A140T9Z6_HUMAN,tr|A0A1W2PR11|A0A1W2PR11_HUMAN,tr|A0A140T930|A0A140T930_HUMAN,tr|B0UXQ0|B0UXQ0_HUMAN,tr|A0A0G2JL56|A0A0G2JL56_HUMAN" 61 2636.1838 1.61 144748 13856 3 2636.189395 879.7352 "HLA class I histocompatibility antigen, A alpha chain OS=Homo sapiens OX=9606 GN=HLA-A PE=1 SV=2" 3.9 2608.8 - 222941 - - - 2.1231 - 3.998 0.52 - 361.1 1 2 0 0.0056 24 0 0 0 1.06E+07 6.58E+06 - - - 7.5546 0.9895 221125_WJC_METTL3_EV_vs_WT_F10.13860.13860.3 0.566 Sep-80 K.FKDPNC[160.03]VGTVLASRPHTLDGR.N "sp|Q96EP5|DAZP1_HUMAN,tr|K7EK33|K7EK33_HUMAN,tr|K7EQ55|K7EQ55_HUMAN,tr|K7EQ02|K7EQ02_HUMAN" 4 2339.1804 2.17 144750 13860 3 2339.181669 780.7341 DAZ-associated protein 1 OS=Homo sapiens OX=9606 GN=DAZAP1 PE=1 SV=1 8.23 2609.3 - 153804 - - - 0.522 - 1.719 0.26 - 60.6 1 2 1 0.0012 21 0 0 0 1.97E+06 9.11E+05 - - - 2.7372 0.9993 221125_WJC_METTL3_EV_vs_WT_F10.13861.13861.3 2.23E-06 Nov-56 K.THINIVVIGHVDSGK.S "sp|Q05639|EF1A2_HUMAN,sp|P68104|EF1A1_HUMAN,sp|Q5VTE0|EF1A3_HUMAN,tr|A0A2R8Y488|A0A2R8Y488_HUMAN,tr|A0A2R8YDN5|A0A2R8YDN5_HUMAN,tr|A0A7I2V659|A0A7I2V659_HUMAN,tr|A0A7I2V3H3|A0A7I2V3H3_HUMAN,tr|Q5JR01|Q5JR01_HUMAN,tr|A0A2U3TZH3|A0A2U3TZH3_HUMAN,tr|A0A7I2V5N4|A0A7I2V5N4_HUMAN,tr|A0A087WVQ9|A0A087WVQ9_HUMAN,tr|A6PW80|A6PW80_HUMAN,tr|A0A087WV01|A0A087WV01_HUMAN,tr|A0A2R8Y660|A0A2R8Y660_HUMAN,tr|A0A6Q8PFK6|A0A6Q8PFK6_HUMAN" 15 1587.8733 0.97 144751 13861 3 1587.882179 530.2984 Elongation factor 1-alpha 2 OS=Homo sapiens OX=9606 GN=EEF1A2 PE=1 SV=1 6.61 2609.4 - 113306 - - - 5.5981 - 2.45 0.516 - 139 1 2 0 0.0089 15 0 0 0 6.04E+06 6.23E+06 - - - 6.6286 1 221125_WJC_METTL3_EV_vs_WT_F10.13863.13863.3 2.31E-06 14/56 K.THINIVVIGHVDSGK[136.11].S "sp|Q05639|EF1A2_HUMAN,sp|P68104|EF1A1_HUMAN,sp|Q5VTE0|EF1A3_HUMAN,tr|A0A2R8Y488|A0A2R8Y488_HUMAN,tr|A0A2R8YDN5|A0A2R8YDN5_HUMAN,tr|A0A7I2V659|A0A7I2V659_HUMAN,tr|A0A7I2V3H3|A0A7I2V3H3_HUMAN,tr|Q5JR01|Q5JR01_HUMAN,tr|A0A2U3TZH3|A0A2U3TZH3_HUMAN,tr|A0A7I2V5N4|A0A7I2V5N4_HUMAN,tr|A0A087WVQ9|A0A087WVQ9_HUMAN,tr|A6PW80|A6PW80_HUMAN,tr|A0A087WV01|A0A087WV01_HUMAN,tr|A0A2R8Y660|A0A2R8Y660_HUMAN,tr|A0A6Q8PFK6|A0A6Q8PFK6_HUMAN" 15 1595.8875 0.97 144753 13863 3 1595.887591 532.9698 Elongation factor 1-alpha 2 OS=Homo sapiens OX=9606 GN=EEF1A2 PE=1 SV=1 6.61 2609.7 - 286418 - - - 0.0633 - 2.732 0.573 - 128.4 1 2 0 0.0001 15 0 0 0 6.04E+06 6.23E+06 - - - 7.5509 0.9945 221125_WJC_METTL3_EV_vs_WT_F10.13867.13867.3 3.84E-10 16/56 A.SAVPELATDPELEK[136.11]K[136.11].L "sp|Q86U44|MTA70_HUMAN,tr|B4E349|B4E349_HUMAN,tr|F5H6D8|F5H6D8_HUMAN,tr|H0YFV6|H0YFV6_HUMAN,tr|B4DTN4|B4DTN4_HUMAN" 5 1641.8796 0 144755 13867 3 1641.884946 548.3005 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 4.41 2610.2 - 967943 - - - 3.2451 - 2.99 0.592 - 317.7 1 1 0 0.0053 15 0 0 0 1.55E+05 7.45E+07 - - - 7.9967 0.9997 221125_WJC_METTL3_EV_vs_WT_F10.13869.13869.4 8.24E-09 16/132 K.QHSSSINAVAWSPSGSHVVSVDK.G "sp|Q676U5|A16L1_HUMAN,tr|E7EVC7|E7EVC7_HUMAN" 2 2378.1615 1.82 144757 13869 4 2378.173515 595.5476 Autophagy-related protein 16-1 OS=Homo sapiens OX=9606 GN=ATG16L1 PE=1 SV=2 6.92 2610.5 - 352983 - - - 5.0577 - 3.553 0.546 - 163.1 1 2 0 0.012 23 0 0 0 5.39E+06 2.97E+06 - - - 4.3858 0.9995 221125_WJC_METTL3_EV_vs_WT_F10.13870.13870.4 1.24E-05 Nov-90 R.ERLEHPVLHVSWNDAR.A "sp|Q8NBJ7|SUMF2_HUMAN,tr|A8MXB9|A8MXB9_HUMAN,tr|F8WA42|F8WA42_HUMAN,tr|H7C3B2|H7C3B2_HUMAN,tr|J3KQJ1|J3KQJ1_HUMAN,tr|C9JL30|C9JL30_HUMAN,tr|A0A494C1B1|A0A494C1B1_HUMAN,tr|C9J660|C9J660_HUMAN" 8 1956.9918 1.2 144758 13870 4 1956.997152 490.2552 Inactive C-alpha-formylglycine-generating enzyme 2 OS=Homo sapiens OX=9606 GN=SUMF2 PE=1 SV=2 6.02 2610.6 - 121397 - - - 2.7133 - 2.655 0.474 - 114.5 1 2 1 0.0053 16 0 0 0 4.51E+06 3.76E+06 - - - 3.6942 0.9958 221125_WJC_METTL3_EV_vs_WT_F10.13871.13871.4 0.00932 9/102 K.VGK[136.11]DHTLEDEDVIQIVK[136.11]K[136.11].- sp|Q9Y295|DRG1_HUMAN 1 2089.1481 0.84 144759 13871 4 2089.154711 523.2943 Developmentally-regulated GTP-binding protein 1 OS=Homo sapiens OX=9606 GN=DRG1 PE=1 SV=1 4.83 2610.8 - 93454.9 - - - 3.1477 - 1.714 0.366 - 47.2 1 2 1 0.0066 18 0 0 0 2.18E+06 2.59E+06 - - - 2.5944 0.9991 221125_WJC_METTL3_EV_vs_WT_F10.13872.13872.4 0.00074 Aug-90 R.ER[166.11]LEHPVLHVSWNDAR[166.11].A "sp|Q8NBJ7|SUMF2_HUMAN,tr|A8MXB9|A8MXB9_HUMAN,tr|F8WA42|F8WA42_HUMAN,tr|H7C3B2|H7C3B2_HUMAN,tr|J3KQJ1|J3KQJ1_HUMAN,tr|C9JL30|C9JL30_HUMAN,tr|A0A494C1B1|A0A494C1B1_HUMAN,tr|C9J660|C9J660_HUMAN" 8 1977.0084 1.69 144760 13872 4 1977.01178 495.2594 Inactive C-alpha-formylglycine-generating enzyme 2 OS=Homo sapiens OX=9606 GN=SUMF2 PE=1 SV=2 6.02 2610.9 - 65766 - - - 1.7188 - 1.87 0.398 - 45.9 1 2 1 0.0034 16 0 0 0 4.16E+06 2.46E+06 - - - 2.9097 0.9164 221125_WJC_METTL3_EV_vs_WT_F10.13881.13881.3 0.0353 Sep-40 K.IRLENEIQTYR.S "sp|P13645|K1C10_HUMAN,tr|A0A1B0GVI3|A0A1B0GVI3_HUMAN" 2 1433.7627 246.83 144765 13881 3 1433.770092 478.9282 "Keratin, type I cytoskeletal 10 OS=Homo sapiens OX=9606 GN=KRT10 PE=1 SV=6" 6.14 2612.2 - 298133 - - - 5.1717 - 1.722 0.286 - 168.5 1 2 1 0.0074 11 0 0 0 1.51E+07 6.14E+04 - - - 3.2705 1 221125_WJC_METTL3_EV_vs_WT_F10.13887.13887.3 1.86E-10 17/92 R.DGEDQTQDTELVETR[166.11]PAGDGTFQK[136.11].W "sp|P04439|HLAA_HUMAN,sp|P01893|HLAH_HUMAN,sp|P10321|HLAC_HUMAN,tr|A0A1W2PP77|A0A1W2PP77_HUMAN,tr|A0A140T941|A0A140T941_HUMAN,tr|A0A1W2PQS8|A0A1W2PQS8_HUMAN,tr|A0A140T921|A0A140T921_HUMAN,tr|A0A1W2PNZ7|A0A1W2PNZ7_HUMAN,tr|A0A0G2JI36|A0A0G2JI36_HUMAN,tr|A0A140T8W8|A0A140T8W8_HUMAN,tr|Q9GJ45|Q9GJ45_HUMAN,tr|O19617|O19617_HUMAN,tr|Q53Z42|Q53Z42_HUMAN,tr|Q5RJ27|Q5RJ27_HUMAN,tr|Q53YP1|Q53YP1_HUMAN,tr|Q5RIP0|Q5RIP0_HUMAN,tr|Q5SRN5|Q5SRN5_HUMAN,tr|A0A1W2PS24|A0A1W2PS24_HUMAN,tr|A0A0G2JIF2|A0A0G2JIF2_HUMAN,tr|A0A1W2PQD0|A0A1W2PQD0_HUMAN,tr|A0A1W2PRZ0|A0A1W2PRZ0_HUMAN,tr|A0A0G2JH50|A0A0G2JH50_HUMAN,tr|A0A140T9U0|A0A140T9U0_HUMAN,tr|A0A140T955|A0A140T955_HUMAN,tr|A0A0G2JPD3|A0A0G2JPD3_HUMAN,tr|A0A140T9W2|A0A140T9W2_HUMAN,tr|O78179|O78179_HUMAN,tr|A0A140T913|A0A140T913_HUMAN,tr|A2AEA2|A2AEA2_HUMAN,tr|A0A1W2PPQ2|A0A1W2PPQ2_HUMAN,tr|Q5SPM2|Q5SPM2_HUMAN,tr|Q5SUL5|Q5SUL5_HUMAN,tr|A0A140T8Y4|A0A140T8Y4_HUMAN,tr|A0A140T975|A0A140T975_HUMAN,tr|A2BF26|A2BF26_HUMAN,tr|A0A140T933|A0A140T933_HUMAN,tr|A0A140T9H5|A0A140T9H5_HUMAN,tr|A0A1W2PS56|A0A1W2PS56_HUMAN,tr|A0A0G2JIF0|A0A0G2JIF0_HUMAN,tr|A0A1W2PSE7|A0A1W2PSE7_HUMAN,tr|Q5QT33|Q5QT33_HUMAN,tr|A0A140T9J9|A0A140T9J9_HUMAN,tr|A0A1W2PRT9|A0A1W2PRT9_HUMAN,tr|A0A140T9B3|A0A140T9B3_HUMAN,tr|A0A1W2PPF8|A0A1W2PPF8_HUMAN,tr|A0A1W2PRX1|A0A1W2PRX1_HUMAN,tr|A0A140T937|A0A140T937_HUMAN,tr|Q5SRN7|Q5SRN7_HUMAN,tr|A0A1W2PR61|A0A1W2PR61_HUMAN,tr|A0A140T912|A0A140T912_HUMAN,tr|A0A140T962|A0A140T962_HUMAN,tr|A0A140T9M0|A0A140T9M0_HUMAN,tr|A0A140T9I0|A0A140T9I0_HUMAN,tr|A0A140T9U8|A0A140T9U8_HUMAN,tr|A0A140T9X5|A0A140T9X5_HUMAN,tr|A0A1W2PS39|A0A1W2PS39_HUMAN,tr|A0A140T9Z6|A0A140T9Z6_HUMAN,tr|A0A1W2PR11|A0A1W2PR11_HUMAN,tr|A0A140T930|A0A140T930_HUMAN,tr|B0UXQ0|B0UXQ0_HUMAN,tr|A0A0G2JL56|A0A0G2JL56_HUMAN" 61 2654.2063 1.61 144769 13887 3 2654.214577 885.7427 "HLA class I histocompatibility antigen, A alpha chain OS=Homo sapiens OX=9606 GN=HLA-A PE=1 SV=2" 3.9 2613 - 307147 - - - 3.1305 - 3.679 0.698 - 316.8 1 2 0 0.0083 24 0 0 0 1.06E+07 6.58E+06 - - - 9.3452 0.9993 221125_WJC_METTL3_EV_vs_WT_F10.13899.13899.4 1.73E-08 15/90 R.YTK[136.11]EELLDIK[136.11]ELPHSK[136.11].Q "sp|Q9NRA8|4ET_HUMAN,tr|B1AKL6|B1AKL6_HUMAN,tr|B1AKL5|B1AKL5_HUMAN,tr|B1AKL4|B1AKL4_HUMAN" 4 1966.0837 1.04 144777 13899 4 1966.092633 492.5282 Eukaryotic translation initiation factor 4E transporter OS=Homo sapiens OX=9606 GN=EIF4ENIF1 PE=1 SV=2 5.53 2614.6 - 202929 - - - 4.5212 - 3.037 0.555 - 100.3 1 2 2 0.0089 16 0 0 0 5.75E+06 5.50E+06 - - - 4.4456 0.9996 221125_WJC_METTL3_EV_vs_WT_F10.13900.13900.4 7.74E-14 25/216 K.AEAAAAAMATPARPGEAEDAAERPLQDEPAAAAGPGK.G sp|Q9NUD5|ZCHC3_HUMAN 1 3528.6903 2.12 144778 13900 4 3528.708687 883.1799 Zinc finger CCHC domain-containing protein 3 OS=Homo sapiens OX=9606 GN=ZCCHC3 PE=1 SV=2 4.25 2614.8 - 192879 - - - 5.2039 - 4.292 0.535 - 344.1 1 2 0 0.0184 37 0 0 0 2.06E+06 9.74E+05 - - - 4.3046 0.9797 221125_WJC_METTL3_EV_vs_WT_F10.13905.13905.4 4.45E-06 9/168 V.PTAPTSGGPK[136.11]PSTASAVPELATDPELEK[136.11]K[136.11].L "sp|Q86U44|MTA70_HUMAN,tr|B4E349|B4E349_HUMAN,tr|F5H6D8|F5H6D8_HUMAN,tr|H0YFV6|H0YFV6_HUMAN,tr|B4DTN4|B4DTN4_HUMAN" 5 2899.5241 0 144780 13905 4 2899.530259 725.8883 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 4.87 2615.6 - 222523 - - - 2.1297 - 2.653 0.421 - 32.5 1 1 0 0.0062 29 0 0 0 4.88E+04 4.54E+07 - - - 3.1894 0.9788 221125_WJC_METTL3_EV_vs_WT_F10.13906.13906.4 0.000652 11/114 R.RPASHQTFPLQLENGQTVER.T sp|Q9H9G7|AGO3_HUMAN 1 2307.172 1.03 144781 13906 4 2307.186272 577.8003 Protein argonaute-3 OS=Homo sapiens OX=9606 GN=AGO3 PE=1 SV=2 6.76 2615.7 - 208996 - - - 6.1894 - 2.445 0.307 - 83.6 1 2 0 0.0143 20 0 0 0 2.94E+06 2.86E+06 - - - 2.1931 1 221125_WJC_METTL3_EV_vs_WT_F10.13913.13913.3 1.05E-14 29/112 R.VPSAAC[160.03]PPFPPHGAPVSASSSSSSPGGSR.G sp|Q9H7S9|ZN703_HUMAN 1 2734.2769 1.71 144785 13913 3 2734.285666 912.4329 Zinc finger protein 703 OS=Homo sapiens OX=9606 GN=ZNF703 PE=1 SV=1 8.23 2616.7 - 407907 - - - 3.1961 - 5.029 0.733 - 489.4 1 2 0 0.0087 29 0 0 0 1.32E+07 7.69E+06 - - - 10.4258 0.9737 221125_WJC_METTL3_EV_vs_WT_F10.13923.13923.3 0.335 Jul-36 R.K[136.11]QDSGHLDLR[166.11].N "sp|Q86U44|MTA70_HUMAN,tr|B4E349|B4E349_HUMAN,tr|F5H6D8|F5H6D8_HUMAN,tr|B4DTN4|B4DTN4_HUMAN" 4 1185.6221 0.02 144793 13923 3 1185.625253 396.2146 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 6.75 2618 - 101295 - - - 2.6551 - 1.289 0.233 - 79.3 1 2 0 0.0031 10 0 0 0 5.90E+04 3.35E+06 - - - 1.8782 0.9895 221125_WJC_METTL3_EV_vs_WT_F10.13940.13940.4 3.19E-05 13/84 R.HIDALEDK[136.11]IDEEVR[166.11]R[166.11].F "sp|P49959|MRE11_HUMAN,tr|F8W7U8|F8W7U8_HUMAN" 2 1864.9637 1.22 144804 13940 4 1864.97894 467.2482 Double-strand break repair protein MRE11 OS=Homo sapiens OX=9606 GN=MRE11 PE=1 SV=3 4.58 2620.4 - 119940 - - - 8.1557 - 2.195 0.506 - 155.3 1 2 1 0.0152 15 0 0 0 2.14E+07 1.76E+07 - - - 3.9073 0.9992 221125_WJC_METTL3_EV_vs_WT_F10.13954.13954.4 0.000703 9/132 K.RPEPSTLENITDDKYATVSSPSK.S sp|Q01804|OTUD4_HUMAN 1 2534.25 1.7 144814 13954 4 2534.256322 634.5698 OTU domain-containing protein 4 OS=Homo sapiens OX=9606 GN=OTUD4 PE=1 SV=4 4.78 2622.4 - 132236 - - - 2.484 - 2.246 0.429 - 52.1 1 2 1 0.0063 23 0 0 0 1.87E+07 1.10E+07 - - - 3.2204 1 221125_WJC_METTL3_EV_vs_WT_F10.13955.13955.3 5.48E-08 19/112 R.VPSAAC[160.03]PPFPPHGAPVSASSSSSSPGGSR[166.11].G sp|Q9H7S9|ZN703_HUMAN 1 2744.2852 2.21 144815 13955 3 2744.289743 915.769 Zinc finger protein 703 OS=Homo sapiens OX=9606 GN=ZNF703 PE=1 SV=1 8.23 2622.5 - 232963 - - - 1.6565 - 3.301 0.613 - 136.8 1 2 0 0.0045 29 0 0 0 1.14E+07 5.16E+06 - - - 8.1206 0.9593 221125_WJC_METTL3_EV_vs_WT_F10.13956.13956.4 0.0221 Oct-90 R.SK[136.11]VDEAVAVLQAHQAK[136.11].E "sp|Q9H361|PABP3_HUMAN,sp|P11940|PABP1_HUMAN,tr|H0YAS6|H0YAS6_HUMAN,tr|H0YB75|H0YB75_HUMAN,tr|H0YAS7|H0YAS7_HUMAN,tr|A0A7I2YQE4|A0A7I2YQE4_HUMAN,tr|A0A7I2V649|A0A7I2V649_HUMAN,tr|H0YC10|H0YC10_HUMAN,tr|H0YAR2|H0YAR2_HUMAN,tr|E7ERJ7|E7ERJ7_HUMAN,tr|A0A7I2YQ88|A0A7I2YQ88_HUMAN,tr|A0A087WTT1|A0A087WTT1_HUMAN,tr|A0A7I2YQ90|A0A7I2YQ90_HUMAN,tr|A0A7I2V4N4|A0A7I2V4N4_HUMAN,tr|E7EQV3|E7EQV3_HUMAN" 15 1708.9443 1.39 144816 13956 4 1708.952244 428.2433 Polyadenylate-binding protein 3 OS=Homo sapiens OX=9606 GN=PABPC3 PE=1 SV=2 6.47 2622.6 - 140355 - - - 4.6584 - 1.741 0.302 - 49.6 1 2 1 0.008 16 0 0 0 6.16E+06 4.43E+06 - - - 2.0477 0.9957 221125_WJC_METTL3_EV_vs_WT_F10.13958.13958.4 0.000254 Nov-90 R.SKVDEAVAVLQAHQAK.E "sp|Q9H361|PABP3_HUMAN,sp|P11940|PABP1_HUMAN,tr|H0YAS6|H0YAS6_HUMAN,tr|H0YB75|H0YB75_HUMAN,tr|H0YAS7|H0YAS7_HUMAN,tr|A0A7I2YQE4|A0A7I2YQE4_HUMAN,tr|A0A7I2V649|A0A7I2V649_HUMAN,tr|H0YC10|H0YC10_HUMAN,tr|H0YAR2|H0YAR2_HUMAN,tr|E7ERJ7|E7ERJ7_HUMAN,tr|A0A7I2YQ88|A0A7I2YQ88_HUMAN,tr|A0A087WTT1|A0A087WTT1_HUMAN,tr|A0A7I2YQ90|A0A7I2YQ90_HUMAN,tr|A0A7I2V4N4|A0A7I2V4N4_HUMAN,tr|E7EQV3|E7EQV3_HUMAN" 15 1692.9159 1.39 144818 13958 4 1692.924482 424.2362 Polyadenylate-binding protein 3 OS=Homo sapiens OX=9606 GN=PABPC3 PE=1 SV=2 6.47 2622.9 - 135068 - - - 5.0794 - 2.06 0.446 - 88.9 1 2 1 0.0086 16 0 0 0 6.14E+06 4.42E+06 - - - 3.3602 0.9949 221125_WJC_METTL3_EV_vs_WT_F10.13962.13962.4 0.000879 12/102 K.DAYRPTTDADKIEDEVTR.Q "sp|Q9UPN3|MACF1_HUMAN,tr|A0A804HL78|A0A804HL78_HUMAN,tr|H3BQK9|H3BQK9_HUMAN,tr|H0Y314|H0Y314_HUMAN,tr|A0A7P0MQR8|A0A7P0MQR8_HUMAN,tr|H0Y390|H0Y390_HUMAN,tr|H0Y4F5|H0Y4F5_HUMAN,tr|H3BPE1|H3BPE1_HUMAN,tr|H0Y6T5|H0Y6T5_HUMAN,tr|A0A590UJG2|A0A590UJG2_HUMAN" 10 2093.9865 0.96 144820 13962 4 2093.998004 524.5039 "Microtubule-actin cross-linking factor 1, isoforms 1\2\3\5 OS=Homo sapiens OX=9606 GN=MACF1 PE=1 SV=4" 4.23 2623.5 - 132916 - - - 5.4738 - 2.245 0.452 - 105.5 1 2 1 0.0115 18 0 0 0 4.02E+06 4.17E+06 - - - 3.4341 0.9998 221125_WJC_METTL3_EV_vs_WT_F10.13963.13963.4 9.73E-06 11/144 R.FSTHESAAHAIVSVNGTTIEGHVVK[136.11].C sp|Q01085|TIAR_HUMAN 1 2598.3282 1.87 144821 13963 4 2598.337413 650.5893 Nucleolysin TIAR OS=Homo sapiens OX=9606 GN=TIAL1 PE=1 SV=1 6.27 2623.6 - 94555.6 - - - 3.5592 - 2.153 0.508 - 72.6 1 2 0 0.0092 25 0 0 0 1.87E+07 9.98E+06 - - - 3.889 0.9997 221125_WJC_METTL3_EV_vs_WT_F10.13964.13964.4 2.81E-06 11/144 R.FSTHESAAHAIVSVNGTTIEGHVVK.C sp|Q01085|TIAR_HUMAN 1 2590.314 1.87 144822 13964 4 2590.32612 648.5858 Nucleolysin TIAR OS=Homo sapiens OX=9606 GN=TIAL1 PE=1 SV=1 6.27 2623.7 - 143100 - - - 4.6925 - 2.084 0.542 - 78.5 1 2 0 0.0122 25 0 0 0 1.87E+07 9.98E+06 - - - 4.1738 0.9926 221125_WJC_METTL3_EV_vs_WT_F10.13986.13986.4 0.000934 12/132 R.K[136.11]LDDTPSGAGK[136.11]FPAGHSVIQLAR[166.11].R "sp|Q9HC52|CBX8_HUMAN,tr|C9J6K3|C9J6K3_HUMAN" 2 2390.2917 3.15 144833 13986 4 2390.304001 598.5802 Chromobox protein homolog 8 OS=Homo sapiens OX=9606 GN=CBX8 PE=1 SV=3 8.6 2626.8 - 172079 - - - 5.1617 - 2.115 0.414 - 96.9 1 2 1 0.0123 23 0 0 0 1.70E+07 5.39E+06 - - - 3.0687 0.9642 221125_WJC_METTL3_EV_vs_WT_F10.13987.13987.3 5.51E-06 Jul-64 K.K[136.11]ILDSVGIEADDDR[166.11]LNK[136.11].V sp|P05387|RLA2_HUMAN 1 1926.0268 1.33 144834 13987 3 1926.043762 643.0162 60S acidic ribosomal protein P2 OS=Homo sapiens OX=9606 GN=RPLP2 PE=1 SV=1 4.36 2626.9 - 85833.8 - - - 8.7854 - 1.618 0.512 - 38.8 1 2 1 0.0169 17 0 0 0 6.24E+06 4.71E+06 - - - 5.4592 0.9997 221125_WJC_METTL3_EV_vs_WT_F10.13992.13992.3 0.000721 17/60 R.SK[136.11]VDEAVAVLQAHQAK[136.11].E "sp|Q9H361|PABP3_HUMAN,sp|P11940|PABP1_HUMAN,tr|H0YAS6|H0YAS6_HUMAN,tr|H0YB75|H0YB75_HUMAN,tr|H0YAS7|H0YAS7_HUMAN,tr|A0A7I2YQE4|A0A7I2YQE4_HUMAN,tr|A0A7I2V649|A0A7I2V649_HUMAN,tr|H0YC10|H0YC10_HUMAN,tr|H0YAR2|H0YAR2_HUMAN,tr|E7ERJ7|E7ERJ7_HUMAN,tr|A0A7I2YQ88|A0A7I2YQ88_HUMAN,tr|A0A087WTT1|A0A087WTT1_HUMAN,tr|A0A7I2YQ90|A0A7I2YQ90_HUMAN,tr|A0A7I2V4N4|A0A7I2V4N4_HUMAN,tr|E7EQV3|E7EQV3_HUMAN" 15 1708.9443 0.93 144837 13992 3 1708.949471 570.6554 Polyadenylate-binding protein 3 OS=Homo sapiens OX=9606 GN=PABPC3 PE=1 SV=2 6.47 2627.6 - 458288 - - - 3.0358 - 3.186 0.544 - 289.4 1 2 1 0.0052 16 0 0 0 1.19E+07 1.28E+07 - - - 7.5769 0.9958 221125_WJC_METTL3_EV_vs_WT_F10.13993.13993.3 0.000132 10/132 K.GEGESPPVNGTDEAAGATGDAIEPAPPSQGAEAK[136.11].G sp|P49006|MRP_HUMAN 1 3184.4524 2.69 144838 13993 3 3185.446871 1062.4914 MARCKS-related protein OS=Homo sapiens OX=9606 GN=MARCKSL1 PE=1 SV=2 3.71 2627.8 - 62070.8 - - - 312.2973 - 2 0.55 - 50.4 1 2 0 0.9945 34 0 0 0 3.28E+06 1.22E+06 - - - 5.9912 0.9991 221125_WJC_METTL3_EV_vs_WT_F10.13998.13998.4 4.23E-05 19/84 R.HIDALEDKIDEEVRR.F "sp|P49959|MRE11_HUMAN,tr|F8W7U8|F8W7U8_HUMAN" 2 1836.933 1.22 144841 13998 4 1836.940746 460.2405 Double-strand break repair protein MRE11 OS=Homo sapiens OX=9606 GN=MRE11 PE=1 SV=3 4.58 2628.5 - 294434 - - - 4.2223 - 3.343 0.505 - 360.6 1 2 1 0.0078 15 0 0 0 2.20E+07 1.81E+07 - - - 4.0512 0.9982 221125_WJC_METTL3_EV_vs_WT_F10.13999.13999.3 0.00145 Nov-56 R.STSHK[136.11]PDEIYGMIER[166.11].L sp|Q86U44|MTA70_HUMAN 1 1779.8581 0 144842 13999 3 1779.867084 594.2933 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 5.42 2628.6 - 229306 - - - 5.0734 - 2.16 0.414 - 154.1 1 2 0 0.009 15 0 0 0 6.90E+05 1.47E+08 - - - 5.1627 1 221125_WJC_METTL3_EV_vs_WT_F10.14002.14002.4 3.22E-11 26/132 R.KLDDTPSGAGKFPAGHSVIQLAR.R "sp|Q9HC52|CBX8_HUMAN,tr|C9J6K3|C9J6K3_HUMAN" 2 2364.255 3.15 144843 14002 4 2364.265637 592.071 Chromobox protein homolog 8 OS=Homo sapiens OX=9606 GN=CBX8 PE=1 SV=3 8.6 2629 - 478896 - - - 4.5021 - 4.397 0.644 - 508.1 1 2 1 0.0106 23 0 0 0 1.70E+07 5.39E+06 - - - 5.3082 0.9964 221125_WJC_METTL3_EV_vs_WT_F10.14003.14003.3 8.95E-06 Dec-64 K.DKQNKPTGFALGSIEGR.V "sp|P78406|RAE1L_HUMAN,tr|E9PQ57|E9PQ57_HUMAN" 2 1816.9432 1.63 144844 14003 3 1816.953857 606.655 mRNA export factor OS=Homo sapiens OX=9606 GN=RAE1 PE=1 SV=1 8.59 2629.2 - 227962 - - - 5.8868 - 2.528 0.523 - 98.3 1 2 1 0.0107 17 0 0 0 5.81E+07 3.55E+07 - - - 6.7109 1 221125_WJC_METTL3_EV_vs_WT_F10.14004.14004.4 5.63E-17 26/168 R.R[166.11]ATAPVPTVGEGYGYGHESELSQASAAAR[166.11].N "sp|Q9BWF3|RBM4_HUMAN,tr|E9PB51|E9PB51_HUMAN" 2 2951.4277 1.16 144845 14004 4 2951.438148 738.8642 RNA-binding protein 4 OS=Homo sapiens OX=9606 GN=RBM4 PE=1 SV=1 5.5 2629.3 - 575207 - - - 3.5559 - 4.95 0.708 - 244.3 1 2 0 0.0105 29 0 0 0 2.23E+07 1.93E+07 - - - 5.8784 0.999 221125_WJC_METTL3_EV_vs_WT_F10.14005.14005.3 1.71E-06 12/132 K.GEGESPPVNGTDEAAGATGDAIEPAPPSQGAEAK.G sp|P49006|MRP_HUMAN 1 3176.4382 3.11 144846 14005 3 3177.439731 1059.82 MARCKS-related protein OS=Homo sapiens OX=9606 GN=MARCKSL1 PE=1 SV=2 3.71 2629.4 - 108459 - - - 315.3079 - 2.13 0.552 - 67.9 1 2 0 1.0016 34 0 0 0 2.02E+07 6.50E+06 - - - 6.1564 0.9857 221125_WJC_METTL3_EV_vs_WT_F10.14009.14009.4 0.0087 Dec-96 K.DKQNKPTGFALGSIEGR.V "sp|P78406|RAE1L_HUMAN,tr|E9PQ57|E9PQ57_HUMAN" 2 1816.9432 1.73 144848 14009 4 1816.952986 455.2431 mRNA export factor OS=Homo sapiens OX=9606 GN=RAE1 PE=1 SV=1 8.59 2630 - 359162 - - - 5.4074 - 2.46 0.375 - 106.5 1 2 1 0.0098 17 0 0 0 4.64E+07 2.68E+07 - - - 2.7998 0.9998 221125_WJC_METTL3_EV_vs_WT_F10.14010.14010.3 1.64E-07 15/64 K.DK[136.11]QNK[136.11]PTGFALGSIEGR[166.11].V "sp|P78406|RAE1L_HUMAN,tr|E9PQ57|E9PQ57_HUMAN" 2 1842.9798 1.62 144849 14010 3 1842.984594 615.3339 mRNA export factor OS=Homo sapiens OX=9606 GN=RAE1 PE=1 SV=1 8.59 2630.1 - 268688 - - - 2.5844 - 3.211 0.549 - 279.6 1 2 1 0.0048 17 0 0 0 5.81E+07 3.58E+07 - - - 7.6066 1 221125_WJC_METTL3_EV_vs_WT_F10.14011.14011.4 3.50E-20 40/168 R.RATAPVPTVGEGYGYGHESELSQASAAAR.N "sp|Q9BWF3|RBM4_HUMAN,tr|E9PB51|E9PB51_HUMAN" 2 2931.4111 1.17 144850 14011 4 2931.427272 733.8601 RNA-binding protein 4 OS=Homo sapiens OX=9606 GN=RBM4 PE=1 SV=1 5.5 2630.3 - 977096 - - - 5.5124 - 6.093 0.777 - 733.6 1 2 0 0.0162 29 0 0 0 2.22E+07 1.90E+07 - - - 6.5415 1 221125_WJC_METTL3_EV_vs_WT_F10.14012.14012.4 6.70E-13 24/114 R.SLENYHFVDEHGK[136.11]DQGINIR[166.11].Q sp|Q14677|EPN4_HUMAN 1 2388.1577 1.59 144851 14012 4 2388.171322 598.0467 Clathrin interactor 1 OS=Homo sapiens OX=9606 GN=CLINT1 PE=1 SV=1 5.3 2630.4 - 569402 - - - 5.6864 - 4.584 0.701 - 264.2 1 2 1 0.0136 20 0 0 0 3.58E+08 2.25E+08 - - - 5.8328 1 221125_WJC_METTL3_EV_vs_WT_F10.14013.14013.3 1.18E-21 29/120 R.KGTGVVQPLPAAQTVTVSQGSQTEAESAAAK.K "sp|P78364|PHC1_HUMAN,tr|J3KQH6|J3KQH6_HUMAN" 2 3010.5571 4.86 144852 14013 3 3010.569269 1004.5263 Polyhomeotic-like protein 1 OS=Homo sapiens OX=9606 GN=PHC1 PE=1 SV=3 6.14 2630.5 - 246124 - - - 4.0395 - 5.23 0.812 - 799.9 1 2 0 0.0122 31 0 0 0 4.22E+07 8.68E+06 - - - 11.3958 1 221125_WJC_METTL3_EV_vs_WT_F10.14014.14014.4 8.30E-09 18/180 R.KGTGVVQPLPAAQTVTVSQGSQTEAESAAAK.K "sp|P78364|PHC1_HUMAN,tr|J3KQH6|J3KQH6_HUMAN" 2 3010.5571 5.39 144853 14014 4 3010.574369 753.6466 Polyhomeotic-like protein 1 OS=Homo sapiens OX=9606 GN=PHC1 PE=1 SV=3 6.14 2630.6 - 172546 - - - 5.7335 - 3.688 0.634 - 137.4 1 2 0 0.0173 31 0 0 0 1.71E+07 3.17E+06 - - - 5.1362 0.9968 221125_WJC_METTL3_EV_vs_WT_F10.14015.14015.4 3.28E-05 14/156 R.LQAPQASVTAPSEQTTEFGIHKPHLGK.S sp|Q6WKZ4|RFIP1_HUMAN 1 2871.4879 1.48 144854 14015 4 2871.506332 718.8793 Rab11 family-interacting protein 1 OS=Homo sapiens OX=9606 GN=RAB11FIP1 PE=1 SV=3 6.92 2630.8 - 150483 - - - 6.4169 - 2.616 0.426 - 94.5 1 2 0 0.0184 27 0 0 0 2.64E+06 1.78E+06 - - - 3.2297 1 221125_WJC_METTL3_EV_vs_WT_F10.14018.14018.4 2.26E-14 29/114 R.SLENYHFVDEHGKDQGINIR.Q sp|Q14677|EPN4_HUMAN 1 2370.1353 1.59 144855 14018 4 2370.145147 593.5411 Clathrin interactor 1 OS=Homo sapiens OX=9606 GN=CLINT1 PE=1 SV=1 5.3 2631.2 - 2.97E+06 - - - 4.1664 - 4.639 0.668 - 444.7 1 2 1 0.0099 20 0 0 0 3.58E+08 2.25E+08 - - - 5.5506 0.9997 221125_WJC_METTL3_EV_vs_WT_F10.14020.14020.4 0.00554 9/114 K.VAHPIR[166.11]PK[136.11]PPSATSIPAILK[136.11].A "sp|Q9UMS4|PRP19_HUMAN,tr|F5GY56|F5GY56_HUMAN" 2 2118.2888 1.43 144857 14020 4 2118.295851 530.5795 Pre-mRNA-processing factor 19 OS=Homo sapiens OX=9606 GN=PRPF19 PE=1 SV=1 11.17 2631.5 - 282398 - - - 3.3522 - 2.05 0.449 - 53.3 1 2 0 0.0071 20 0 0 0 3.06E+07 2.15E+07 - - - 3.3721 1 221125_WJC_METTL3_EV_vs_WT_F10.14022.14022.3 1.58E-07 8/112 R.R[166.11]ATAPVPTVGEGYGYGHESELSQASAAAR[166.11].N "sp|Q9BWF3|RBM4_HUMAN,tr|E9PB51|E9PB51_HUMAN" 2 2951.4277 1.62 144859 14022 3 2951.434157 984.8165 RNA-binding protein 4 OS=Homo sapiens OX=9606 GN=RBM4 PE=1 SV=1 5.5 2631.8 - 87865.4 - - - 2.2037 - 2.441 0.59 - 20.8 1 2 0 0.0065 29 0 0 0 1.51E+06 9.31E+05 - - - 7.1692 1 221125_WJC_METTL3_EV_vs_WT_F10.14026.14026.3 4.94E-10 23/76 R.SLENYHFVDEHGKDQGINIR.Q sp|Q14677|EPN4_HUMAN 1 2370.1353 1.52 144861 14026 3 2370.14243 791.0524 Clathrin interactor 1 OS=Homo sapiens OX=9606 GN=CLINT1 PE=1 SV=1 5.3 2632.3 - 425481 - - - 3.0201 - 4.783 0.705 - 601.6 1 2 1 0.0072 20 0 0 0 3.21E+07 2.11E+07 - - - 10.195 0.9999 221125_WJC_METTL3_EV_vs_WT_F10.14027.14027.3 3.89E-05 8/112 R.SPISDNSGC[160.03]DAPGNSNPSLSVPSSAESEK.Q "sp|Q99590|SCAFB_HUMAN,tr|F8VXG7|F8VXG7_HUMAN,tr|A0A0A0MTP7|A0A0A0MTP7_HUMAN" 3 2889.257 1.17 144862 14027 3 2889.264795 964.093 Protein SCAF11 OS=Homo sapiens OX=9606 GN=SCAF11 PE=1 SV=2 3.92 2632.4 - 98066.8 - - - 2.6841 - 2.067 0.598 - 27.2 1 2 0 0.0078 29 0 0 0 4.17E+06 3.56E+06 - - - 6.8754 1 221125_WJC_METTL3_EV_vs_WT_F10.14032.14032.3 3.26E-17 24/76 R.SLENYHFVDEHGK[136.11]DQGINIR[166.11].Q sp|Q14677|EPN4_HUMAN 1 2388.1577 1.52 144865 14032 3 2388.163075 797.0599 Clathrin interactor 1 OS=Homo sapiens OX=9606 GN=CLINT1 PE=1 SV=1 5.3 2633.1 - 552470 - - - 2.2331 - 5.2 0.724 - 580 1 2 1 0.0053 20 0 0 0 3.21E+07 2.11E+07 - - - 10.6101 1 221125_WJC_METTL3_EV_vs_WT_F10.14033.14033.3 2.05E-08 Dec-84 R.QNTLGHNTQTSIAQDFSSEQGR.T "sp|P09630|HXC6_HUMAN,tr|D6RBH4|D6RBH4_HUMAN,tr|D6RC34|D6RC34_HUMAN" 3 2418.116 1.51 144866 14033 3 2418.122464 807.0459 Homeobox protein Hox-C6 OS=Homo sapiens OX=9606 GN=HOXC6 PE=2 SV=3 5.32 2633.3 - 402478 - - - 2.6761 - 3.01 0.58 - 148.4 1 2 0 0.0065 22 0 0 0 1.83E+07 1.22E+07 - - - 7.6172 1 221125_WJC_METTL3_EV_vs_WT_F10.14039.14039.3 3.17E-15 18/120 R.K[136.11]GTGVVQPLPAAQTVTVSQGSQTEAESAAAK[136.11].K "sp|P78364|PHC1_HUMAN,tr|J3KQH6|J3KQH6_HUMAN" 2 3026.5855 4.85 144869 14039 3 3026.587709 1009.8691 Polyhomeotic-like protein 1 OS=Homo sapiens OX=9606 GN=PHC1 PE=1 SV=3 6.14 2634 - 210358 - - - 0.7272 - 4.25 0.764 - 217.8 1 2 0 0.0022 31 0 0 0 4.21E+07 8.68E+06 - - - 10.3861 0.9998 221125_WJC_METTL3_EV_vs_WT_F10.14043.14043.3 0.000759 Aug-52 K.SQIHDIVLVGGSTR[166.11].L "sp|P11142|HSP7C_HUMAN,tr|E9PNE6|E9PNE6_HUMAN,tr|A8K7Q2|A8K7Q2_HUMAN,tr|E9PKE3|E9PKE3_HUMAN,tr|E9PN89|E9PN89_HUMAN" 5 1490.8081 0.14 144870 14043 3 1490.810663 497.9433 Heat shock cognate 71 kDa protein OS=Homo sapiens OX=9606 GN=HSPA8 PE=1 SV=1 6.46 2634.6 - 179733 - - - 1.7454 - 1.706 0.443 - 84.1 1 2 0 0.0026 14 0 0 0 3.87E+06 2.74E+07 - - - 4.8978 1 221125_WJC_METTL3_EV_vs_WT_F10.14075.14075.4 2.51E-11 16/114 K.K[136.11]NQDDFEC[160.03]VTTLEGHENEVK[136.11].S sp|O76071|CIAO1_HUMAN 1 2407.0933 1.54 144888 14075 4 2407.097272 602.7806 Probable cytosolic iron-sulfur protein assembly protein CIAO1 OS=Homo sapiens OX=9606 GN=CIAO1 PE=1 SV=1 4.35 2638.8 - 246783 - - - 1.663 - 3.541 0.613 - 202.9 1 2 0 0.004 20 0 0 0 7.45E+06 4.84E+06 - - - 4.9832 0.998 221125_WJC_METTL3_EV_vs_WT_F10.14080.14080.3 0.00474 Sep-52 K.SQIHDIVLVGGSTR.L "sp|P11142|HSP7C_HUMAN,tr|E9PNE6|E9PNE6_HUMAN,tr|A8K7Q2|A8K7Q2_HUMAN,tr|E9PKE3|E9PKE3_HUMAN,tr|E9PN89|E9PN89_HUMAN" 5 1480.7998 0.14 144890 14080 3 1480.804575 494.6072 Heat shock cognate 71 kDa protein OS=Homo sapiens OX=9606 GN=HSPA8 PE=1 SV=1 6.46 2639.6 - 196710 - - - 3.2307 - 1.91 0.33 - 95.4 1 2 0 0.0048 14 0 0 0 3.87E+06 2.74E+07 - - - 3.9375 0.9936 221125_WJC_METTL3_EV_vs_WT_F10.14086.14086.3 2.21E-08 14/88 K.DHTPSQELALTQSVGGDSSADRL.F "sp|Q86U44|MTA70_HUMAN,tr|H0YFV6|H0YFV6_HUMAN" 2 2383.1252 77.08 144893 14086 3 2383.117876 795.3823 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 4.22 2640.3 - 495671 - - - -3.0569 - 3.532 0.532 - 129 1 1 0 -0.0073 23 0 0 0 1.88E+07 2.44E+05 - - - 7.4295 0.9999 221125_WJC_METTL3_EV_vs_WT_F10.14088.14088.2 7.98E-08 26-Oct K.SQIHDIVLVGGSTR[166.11].L "sp|P11142|HSP7C_HUMAN,tr|E9PNE6|E9PNE6_HUMAN,tr|A8K7Q2|A8K7Q2_HUMAN,tr|E9PKE3|E9PKE3_HUMAN,tr|E9PN89|E9PN89_HUMAN" 5 1490.8081 0.001 144895 14088 2 1490.80857 746.4113 Heat shock cognate 71 kDa protein OS=Homo sapiens OX=9606 GN=HSPA8 PE=1 SV=1 6.46 2640.6 - 96505.9 - - - 0.3414 - 2.375 0.593 - 316.5 1 2 0 0.0005 14 0 0 0 0.00E+00 1.26E+06 - - - 5.5914 0.9889 221125_WJC_METTL3_EV_vs_WT_F10.14089.14089.4 0.223 8/144 R.GGTFQMGGSSSHNRPSGSNVDTLLR.L sp|Q7Z6Z7|HUWE1_HUMAN 1 2561.2041 0.31 144896 14089 4 2561.209662 641.3083 E3 ubiquitin-protein ligase HUWE1 OS=Homo sapiens OX=9606 GN=HUWE1 PE=1 SV=3 9.61 2640.7 - 81633.4 - - - 2.1728 - 1.875 0.219 - 31 1 2 0 0.0056 25 0 0 0 4.15E+06 1.36E+07 - - - 1.3306 1 221125_WJC_METTL3_EV_vs_WT_F10.14105.14105.3 1.22E-08 16/84 K.DHTPSQELALTQSVGGDSSADR[166.11].L "sp|Q86U44|MTA70_HUMAN,tr|H0YFV6|H0YFV6_HUMAN" 2 2280.0494 0.001 144906 14105 3 2280.053021 761.0237 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 4.22 2642.9 - 167885 - - - 1.6026 - 3.309 0.618 - 240.3 1 2 0 0.0037 22 0 0 0 0.00E+00 6.17E+06 - - - 8.2661 1 221125_WJC_METTL3_EV_vs_WT_F10.14106.14106.4 6.64E-08 27/198 R.LGEASDSELADADK[136.11]ASVASEVSTTSSTSK[136.11]PPTGR[166.11].R "sp|Q5SW79|CE170_HUMAN,tr|H0Y2V6|H0Y2V6_HUMAN" 2 3376.6328 0.64 144907 14106 4 3376.647327 845.1655 Centrosomal protein of 170 kDa OS=Homo sapiens OX=9606 GN=CEP170 PE=1 SV=1 4.3 2643.1 - 466429 - - - 4.3016 - 4.682 0.619 - 273.6 1 2 1 0.0145 34 0 0 0 5.31E+06 8.23E+06 - - - 5.0701 0.9999 221125_WJC_METTL3_EV_vs_WT_F10.14107.14107.4 7.28E-07 12/126 R.SPLEK[136.11]PHNGLLFPQHGDYQYGR[166.11].N "sp|Q96K37|S35E1_HUMAN,tr|H7C1I0|H7C1I0_HUMAN" 2 2570.2785 1.26 144908 14107 4 2570.286049 643.5769 Solute carrier family 35 member E1 OS=Homo sapiens OX=9606 GN=SLC35E1 PE=1 SV=2 6.66 2643.2 - 171319 - - - 2.9269 - 2.962 0.554 - 100.8 1 2 0 0.0075 22 0 0 0 3.60E+06 2.85E+06 - - - 4.4012 0.9998 221125_WJC_METTL3_EV_vs_WT_F10.14110.14110.4 9.48E-09 15/126 R.SPLEKPHNGLLFPQHGDYQYGR.N "sp|Q96K37|S35E1_HUMAN,tr|H7C1I0|H7C1I0_HUMAN" 2 2552.2561 1.47 144909 14110 4 2552.269827 639.0713 Solute carrier family 35 member E1 OS=Homo sapiens OX=9606 GN=SLC35E1 PE=1 SV=2 6.66 2643.6 - 206528 - - - 5.3956 - 2.659 0.619 - 151 1 2 0 0.0138 22 0 0 0 4.26E+06 2.90E+06 - - - 4.93 0.9999 221125_WJC_METTL3_EV_vs_WT_F10.14111.14111.3 0.000235 13/76 K.R[166.11]GLLQDDAHPTLVTYADHSK[136.11].L "sp|Q86U44|MTA70_HUMAN,tr|F5H6D8|F5H6D8_HUMAN,tr|H0YFV6|H0YFV6_HUMAN,tr|B4DTN4|B4DTN4_HUMAN" 4 2254.1461 0.01 144910 14111 3 2254.150957 752.3893 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 5.99 2643.8 - 157059 - - - 2.148 - 2.652 0.479 - 198.9 1 2 0 0.0048 20 0 0 0 1.29E+05 1.28E+07 - - - 6.2452 0.8671 221125_WJC_METTL3_EV_vs_WT_F10.14113.14113.4 0.0382 Nov-84 K.KKPIYINVIRDPIER.L "sp|Q7LGA3|HS2ST_HUMAN,tr|K7EP71|K7EP71_HUMAN" 2 1853.0887 1.14 144912 14113 4 1853.097217 464.2795 Heparan sulfate 2-O-sulfotransferase 1 OS=Homo sapiens OX=9606 GN=HS2ST1 PE=1 SV=1 9.7 2644 - 146701 - - - 4.5945 - 1.916 0.237 - 98.1 1 2 1 0.0085 15 0 0 0 3.23E+06 2.83E+06 - - - 1.5192 0.9977 221125_WJC_METTL3_EV_vs_WT_F10.14118.14118.3 0.0199 May-96 K.LVC[160.03]SGENDNHGQIANLPSAVTSDQK[136.11].S sp|Q8WYP5|ELYS_HUMAN 1 2661.2544 1.37 144915 14118 3 2661.257082 888.0921 Protein ELYS OS=Homo sapiens OX=9606 GN=AHCTF1 PE=1 SV=3 4.54 2644.7 - 69341.9 - - - 1.0048 - 1.279 0.332 - 14.9 1 2 0 0.0027 25 0 0 0 2.95E+06 2.16E+06 - - - 2.8069 1 221125_WJC_METTL3_EV_vs_WT_F10.14120.14120.4 1.45E-13 19/144 K.NLEEGHSSTVAAHYNELQEVGLEK[136.11]R[166.11].S sp|O43148|MCES_HUMAN 1 2827.3856 0.71 144917 14120 4 2827.39366 707.8537 mRNA cap guanine-N7 methyltransferase OS=Homo sapiens OX=9606 GN=RNMT PE=1 SV=1 4.98 2645 - 509195 - - - 2.8613 - 3.808 0.7 - 153.5 1 2 0 0.0081 25 0 0 0 6.87E+06 9.74E+06 - - - 5.7419 0.9994 221125_WJC_METTL3_EV_vs_WT_F10.14121.14121.3 9.43E-06 10/128 R.TVGTPIASVPGSTNTGTVPGSEK[136.11]DSDSMETEEK[136.11].T "sp|Q99460|PSMD1_HUMAN,tr|A0A7I2V4X0|A0A7I2V4X0_HUMAN,tr|A0A7I2V2K8|A0A7I2V2K8_HUMAN,tr|A0A7I2YQY1|A0A7I2YQY1_HUMAN,tr|A0A7I2V523|A0A7I2V523_HUMAN,tr|A0A7I2V641|A0A7I2V641_HUMAN,tr|H7BZR6|H7BZR6_HUMAN,tr|A0A7I2V491|A0A7I2V491_HUMAN,tr|A0A7I2YQI9|A0A7I2YQI9_HUMAN,tr|A0A7I2V262|A0A7I2V262_HUMAN,tr|A0A087WW66|A0A087WW66_HUMAN,tr|A0A7P0MW50|A0A7P0MW50_HUMAN,tr|A0A7I2V4A5|A0A7I2V4A5_HUMAN,tr|A0A7I2V5C8|A0A7I2V5C8_HUMAN,tr|A0A7I2V479|A0A7I2V479_HUMAN" 15 3323.5533 0.67 144918 14121 3 3323.561984 1108.8584 26S proteasome non-ATPase regulatory subunit 1 OS=Homo sapiens OX=9606 GN=PSMD1 PE=1 SV=2 4.08 2645.1 - 252290 - - - 2.6005 - 2.222 0.512 - 35.2 1 2 1 0.0086 33 0 0 0 6.69E+06 9.94E+06 - - - 6.0827 0.9996 221125_WJC_METTL3_EV_vs_WT_F10.14122.14122.3 2.32E-08 14/128 R.TVGTPIASVPGSTNTGTVPGSEKDSDSMETEEK.T "sp|Q99460|PSMD1_HUMAN,tr|A0A7I2V4X0|A0A7I2V4X0_HUMAN,tr|A0A7I2V2K8|A0A7I2V2K8_HUMAN,tr|A0A7I2YQY1|A0A7I2YQY1_HUMAN,tr|A0A7I2V523|A0A7I2V523_HUMAN,tr|A0A7I2V641|A0A7I2V641_HUMAN,tr|H7BZR6|H7BZR6_HUMAN,tr|A0A7I2V491|A0A7I2V491_HUMAN,tr|A0A7I2YQI9|A0A7I2YQI9_HUMAN,tr|A0A7I2V262|A0A7I2V262_HUMAN,tr|A0A087WW66|A0A087WW66_HUMAN,tr|A0A7P0MW50|A0A7P0MW50_HUMAN,tr|A0A7I2V4A5|A0A7I2V4A5_HUMAN,tr|A0A7I2V5C8|A0A7I2V5C8_HUMAN,tr|A0A7I2V479|A0A7I2V479_HUMAN" 15 3307.5249 0.67 144919 14122 3 3307.53636 1103.5156 26S proteasome non-ATPase regulatory subunit 1 OS=Homo sapiens OX=9606 GN=PSMD1 PE=1 SV=2 4.08 2645.2 - 158432 - - - 3.4524 - 2.352 0.626 - 82.8 1 2 1 0.0114 33 0 0 0 6.69E+06 9.94E+06 - - - 7.4838 0.9992 221125_WJC_METTL3_EV_vs_WT_F10.14125.14125.2 1.66E-05 20-Sep R.EEAENTLQSFR.Q "sp|P08670|VIME_HUMAN,tr|B0YJC5|B0YJC5_HUMAN,tr|B0YJC4|B0YJC4_HUMAN" 3 1322.6103 2.93 144920 14125 2 1322.615045 662.3124 Vimentin OS=Homo sapiens OX=9606 GN=VIM PE=1 SV=4 4.25 2645.7 - 134342 - - - 3.6186 - 2.112 0.533 - 370.6 1 2 0 0.0048 11 0 0 0 3.06E+06 1.04E+06 - - - 4.9988 0.9187 221125_WJC_METTL3_EV_vs_WT_F10.14131.14131.4 0.199 Jul-78 R.DHFGFNPEK[136.11]PWGHR[166.11].G "sp|Q9UPN6|SCAF8_HUMAN,tr|A0A0A0MT33|A0A0A0MT33_HUMAN" 2 1740.824 0.54 144923 14131 4 1740.8298 436.2133 SR-related and CTD-associated factor 8 OS=Homo sapiens OX=9606 GN=SCAF8 PE=1 SV=1 6.92 2646.6 - 64029.1 - - - 3.3364 - 1.013 0.192 - 22.1 1 2 0 0.0058 14 0 0 0 1.20E+06 2.20E+06 - - - 0.9003 1 221125_WJC_METTL3_EV_vs_WT_F10.14136.14136.3 2.60E-13 29/112 R.VPSAAC[160.03]PPFPPHGAPVSASSSSSSPGGSR.G sp|Q9H7S9|ZN703_HUMAN 1 2734.2769 2.73 144926 14136 3 2734.283759 912.4329 Zinc finger protein 703 OS=Homo sapiens OX=9606 GN=ZNF703 PE=1 SV=1 8.23 2647.3 - 572400 - - - 2.4986 - 4.833 0.75 - 533.8 1 2 0 0.0068 29 0 0 0 5.76E+07 2.11E+07 - - - 10.5244 0.9975 221125_WJC_METTL3_EV_vs_WT_F10.14143.14143.3 0.00159 Sep-44 R.DLDELSR[166.11]YPEDK[136.11].L "sp|P43243|MATR3_HUMAN,tr|A8MXP9|A8MXP9_HUMAN,tr|D6R991|D6R991_HUMAN,tr|A0A0R4J2E8|A0A0R4J2E8_HUMAN,tr|D6REM6|D6REM6_HUMAN" 5 1496.7114 1.36 144931 14143 3 1496.716552 499.9111 Matrin-3 OS=Homo sapiens OX=9606 GN=MATR3 PE=1 SV=2 4.11 2648.1 - 121750 - - - 3.4603 - 1.909 0.433 - 78.7 1 2 1 0.0052 12 0 0 0 1.24E+07 9.11E+06 - - - 5.1583 1 221125_WJC_METTL3_EV_vs_WT_F10.14151.14151.3 2.83E-06 11/128 K.NTSPTTQPTASGAGAPVMTGAGESTNPENSELK.Y sp|Q92908|GATA6_HUMAN 1 3201.4732 6.2 144937 14151 3 3201.477088 1068.165 Transcription factor GATA-6 OS=Homo sapiens OX=9606 GN=GATA6 PE=1 SV=2 4.25 2649.1 - 165340 - - - 1.2207 - 2.419 0.541 - 74.5 1 2 0 0.0039 33 0 0 0 6.16E+06 9.93E+05 - - - 6.6028 1 221125_WJC_METTL3_EV_vs_WT_F10.14158.14158.4 1.83E-12 24/114 K.R[166.11]GLLQDDAHPTLVTYADHSK[136.11].L "sp|Q86U44|MTA70_HUMAN,tr|F5H6D8|F5H6D8_HUMAN,tr|H0YFV6|H0YFV6_HUMAN,tr|B4DTN4|B4DTN4_HUMAN" 4 2254.1461 0.03 144942 14158 4 2254.152196 564.5438 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 5.99 2649.9 - 4.67E+06 - - - 2.6977 - 4.312 0.593 - 571.1 1 2 0 0.0061 20 0 0 0 8.50E+06 2.67E+08 - - - 4.8744 0.9999 221125_WJC_METTL3_EV_vs_WT_F10.14167.14167.4 0.000336 9/120 K.DFETLYNDC[160.03]TNASSR[166.11]PGR[166.11]PPK[136.11].R sp|Q9UI36|DACH1_HUMAN 1 2452.1436 1.96 144949 14167 4 2452.15012 614.0432 Dachshund homolog 1 OS=Homo sapiens OX=9606 GN=DACH1 PE=1 SV=4 6.11 2651.2 - 217885 - - - 2.6744 - 1.767 0.479 - 47.3 1 2 0 0.0066 21 0 0 0 2.61E+07 1.33E+07 - - - 3.5816 1 221125_WJC_METTL3_EV_vs_WT_F10.14171.14171.3 7.44E-15 19/76 K.C[160.03]QPVFSFGNSEQTKDENSSK.S sp|P49790|NU153_HUMAN 1 2288.0015 1.61 144951 14171 3 2288.005752 763.6745 Nuclear pore complex protein Nup153 OS=Homo sapiens OX=9606 GN=NUP153 PE=1 SV=2 4.68 2651.7 - 459868 - - - 1.8409 - 3.96 0.71 - 307.7 1 2 1 0.0042 20 0 0 0 1.25E+08 7.77E+07 - - - 9.7934 0.9587 221125_WJC_METTL3_EV_vs_WT_F10.14174.14174.2 3.24E-05 22-Jul K.DHTPSQELALTQ.S "sp|Q86U44|MTA70_HUMAN,tr|H0YFV6|H0YFV6_HUMAN" 2 1338.6416 - 144954 14174 2 1338.644912 670.3281 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 4.35 2652.1 - 240734 - - - 2.5048 - 1.713 0.473 - 161.5 1 1 0 0.0034 12 0 0 0 - - - - - 3.9497 1 221125_WJC_METTL3_EV_vs_WT_F10.14180.14180.3 2.06E-12 26/112 R.VPSAAC[160.03]PPFPPHGAPVSASSSSSSPGGSR[166.11].G sp|Q9H7S9|ZN703_HUMAN 1 2744.2852 2.93 144958 14180 3 2744.286217 915.769 Zinc finger protein 703 OS=Homo sapiens OX=9606 GN=ZNF703 PE=1 SV=1 8.23 2652.9 - 324569 - - - 0.3717 - 4.254 0.695 - 393.4 1 2 0 0.001 29 0 0 0 4.38E+07 1.49E+07 - - - 9.6193 1 221125_WJC_METTL3_EV_vs_WT_F10.14190.14190.4 2.12E-08 21/162 R.GQGPSAEAHEGAPDPMPAALHPEEVAAR.L sp|Q9HCJ3|RAVR2_HUMAN 1 2791.2984 2.6 144964 14190 4 2791.300873 698.8319 Ribonucleoprotein PTB-binding 2 OS=Homo sapiens OX=9606 GN=RAVER2 PE=1 SV=2 4.56 2654.2 - 1.81E+06 - - - 0.8892 - 3.52 0.576 - 161.6 1 2 0 0.0025 28 0 0 0 3.66E+07 1.41E+07 - - - 4.6295 1 221125_WJC_METTL3_EV_vs_WT_F10.14191.14191.4 2.14E-06 21/162 R.GQGPSAEAHEGAPDPMPAALHPEEVAAR[166.11].L sp|Q9HCJ3|RAVR2_HUMAN 1 2801.3067 2.44 144965 14191 4 2801.305805 701.3339 Ribonucleoprotein PTB-binding 2 OS=Homo sapiens OX=9606 GN=RAVER2 PE=1 SV=2 4.56 2654.3 - 1.15E+06 - - - -0.3056 - 3.303 0.528 - 164.8 1 2 0 -0.0009 28 0 0 0 3.66E+07 1.50E+07 - - - 4.1924 1 221125_WJC_METTL3_EV_vs_WT_F10.14192.14192.3 9.89E-10 27/76 K.C[160.03]QPVFSFGNSEQTK[136.11]DENSSK[136.11].S sp|P49790|NU153_HUMAN 1 2304.0299 1.6 144966 14192 3 2304.03103 769.0173 Nuclear pore complex protein Nup153 OS=Homo sapiens OX=9606 GN=NUP153 PE=1 SV=2 4.68 2654.4 - 1.38E+06 - - - 0.4731 - 4.61 0.706 - 690.6 1 2 1 0.0011 20 0 0 0 1.25E+08 7.76E+07 - - - 10.1184 1 221125_WJC_METTL3_EV_vs_WT_F10.14193.14193.4 8.81E-12 17/162 R.TLENPVNVYNPSHSDSLASQQSVASHPR.Q "sp|O15027|SC16A_HUMAN,tr|A0A3F2YNX0|A0A3F2YNX0_HUMAN,tr|A0A3F2YNZ0|A0A3F2YNZ0_HUMAN,tr|F1T0I1|F1T0I1_HUMAN" 4 3033.454 1.24 144967 14193 4 3033.455526 759.3708 Protein transport protein Sec16A OS=Homo sapiens OX=9606 GN=SEC16A PE=1 SV=4 5.92 2654.6 - 413226 - - - 0.4899 - 3.337 0.612 - 81.7 1 2 0 0.0015 28 0 0 0 1.53E+07 1.24E+07 - - - 4.9266 1 221125_WJC_METTL3_EV_vs_WT_F10.14197.14197.4 3.15E-09 18/120 K.DFETLYNDC[160.03]TNASSRPGRPPK.R sp|Q9UI36|DACH1_HUMAN 1 2424.1128 1.96 144969 14197 4 2424.112836 607.0355 Dachshund homolog 1 OS=Homo sapiens OX=9606 GN=DACH1 PE=1 SV=4 6.11 2655.1 - 1.57E+06 - - - 0.0058 - 3.083 0.612 - 203.7 1 2 0 0 21 0 0 0 2.61E+07 1.33E+07 - - - 4.9251 0.9609 221125_WJC_METTL3_EV_vs_WT_F10.14200.14200.4 0.0352 8/162 F.SSASK[136.11]PAASGPLSHPTPLSAPPSSVPLK[136.11].S "sp|P35658|NU214_HUMAN,tr|A0A0A0MSW3|A0A0A0MSW3_HUMAN,tr|A0A494BZU9|A0A494BZU9_HUMAN,tr|A0A494C1F2|A0A494C1F2_HUMAN" 4 2683.4516 4.11 144972 14200 4 2683.45358 671.8702 Nuclear pore complex protein Nup214 OS=Homo sapiens OX=9606 GN=NUP214 PE=1 SV=2 10 2655.5 - 311677 - - - 0.7449 - 1.561 0.365 - 23.4 1 1 0 0.002 28 0 0 0 1.92E+07 4.69E+06 - - - 2.5407 0.9985 221125_WJC_METTL3_EV_vs_WT_F10.14205.14205.4 2.58E-06 18/114 K.DIELHLESSSHQETLDHIQK.Q "sp|Q5BKZ1|ZN326_HUMAN,tr|A0A0A0MRN4|A0A0A0MRN4_HUMAN" 2 2358.1452 1.36 144975 14205 4 2358.151488 590.5436 DBIRD complex subunit ZNF326 OS=Homo sapiens OX=9606 GN=ZNF326 PE=1 SV=2 4.84 2656.1 - 664675 - - - 2.6801 - 2.18 0.321 - 100.5 1 2 0 0.0063 20 0 0 0 3.78E+07 2.79E+07 - - - 2.2788 1 221125_WJC_METTL3_EV_vs_WT_F10.14206.14206.3 6.09E-15 18/100 R.VNDGVC[160.03]DC[160.03]C[160.03]DGTDEYNSGVIC[160.03]ENTC[160.03]K[136.11].E "sp|P14314|GLU2B_HUMAN,tr|K7ELL7|K7ELL7_HUMAN,tr|A0A7I2V2T6|A0A7I2V2T6_HUMAN,tr|K7EKX1|K7EKX1_HUMAN,tr|K7EJ70|K7EJ70_HUMAN,tr|K7EPW7|K7EPW7_HUMAN" 6 3048.1391 1.07 144976 14206 3 3048.134665 1017.0537 Glucosidase 2 subunit beta OS=Homo sapiens OX=9606 GN=PRKCSH PE=1 SV=2 3.66 2656.3 - 322093 - - - -1.4622 - 3.671 0.886 - 314.8 1 2 0 -0.0045 26 0 0 0 1.15E+07 1.07E+07 - - - 11.4087 1 221125_WJC_METTL3_EV_vs_WT_F10.14215.14215.4 8.30E-12 17/96 R.REEMEQLFHDDQGGVTR.W "sp|Q15643|TRIPB_HUMAN,tr|H0YJ97|H0YJ97_HUMAN" 2 2045.9225 1.52 144982 14215 4 2045.923404 512.4879 Thyroid receptor-interacting protein 11 OS=Homo sapiens OX=9606 GN=TRIP11 PE=1 SV=3 4.5 2657.4 - 239887 - - - 0.4409 - 3.529 0.64 - 343 1 2 0 0.0009 17 0 0 0 5.54E+06 3.64E+06 - - - 5.2341 1 221125_WJC_METTL3_EV_vs_WT_F10.14219.14219.4 2.12E-06 18/114 K.DIELHLESSSHQETLDHIQK[136.11].Q "sp|Q5BKZ1|ZN326_HUMAN,tr|A0A0A0MRN4|A0A0A0MRN4_HUMAN" 2 2366.1594 1.37 144984 14219 4 2366.158629 592.5471 DBIRD complex subunit ZNF326 OS=Homo sapiens OX=9606 GN=ZNF326 PE=1 SV=2 4.84 2657.9 - 1.04E+06 - - - -0.3123 - 3.21 0.523 - 97.1 1 2 0 -0.0007 20 0 0 0 3.77E+07 2.75E+07 - - - 4.1679 1 221125_WJC_METTL3_EV_vs_WT_F10.14220.14220.3 7.86E-13 18/100 R.VNDGVC[160.03]DC[160.03]C[160.03]DGTDEYNSGVIC[160.03]ENTC[160.03]K.E "sp|P14314|GLU2B_HUMAN,tr|K7ELL7|K7ELL7_HUMAN,tr|A0A7I2V2T6|A0A7I2V2T6_HUMAN,tr|K7EKX1|K7EKX1_HUMAN,tr|K7EJ70|K7EJ70_HUMAN,tr|K7EPW7|K7EPW7_HUMAN" 6 3040.1249 1.07 144985 14220 3 3040.124245 1014.3823 Glucosidase 2 subunit beta OS=Homo sapiens OX=9606 GN=PRKCSH PE=1 SV=2 3.66 2658 - 477579 - - - -0.2227 - 3.262 0.874 - 335.9 1 2 0 -0.0007 26 0 0 0 1.15E+07 1.07E+07 - - - 11.0042 1 221125_WJC_METTL3_EV_vs_WT_F10.14226.14226.4 3.73E-11 18/96 R.R[166.11]EEMEQLFHDDQGGVTR[166.11].W "sp|Q15643|TRIPB_HUMAN,tr|H0YJ97|H0YJ97_HUMAN" 2 2065.939 1.52 144988 14226 4 2065.935553 517.492 Thyroid receptor-interacting protein 11 OS=Homo sapiens OX=9606 GN=TRIP11 PE=1 SV=3 4.5 2658.8 - 191129 - - - -1.6888 - 3.538 0.654 - 359.8 1 2 0 -0.0035 17 0 0 0 5.54E+06 3.64E+06 - - - 5.3562 1 221125_WJC_METTL3_EV_vs_WT_F10.14235.14235.3 1.07E-13 21/84 R.R[166.11]DDIEDGDSMISSATSDTGSAK[136.11].R "sp|Q86U86|PB1_HUMAN,tr|H0Y5B5|H0Y5B5_HUMAN,tr|E7EVG2|E7EVG2_HUMAN" 3 2274.9877 1.68 144993 14235 3 2274.985671 759.3365 Protein polybromo-1 OS=Homo sapiens OX=9606 GN=PBRM1 PE=1 SV=1 3.9 2659.9 - 731128 - - - -0.8848 - 3.69 0.742 - 529.7 1 2 0 -0.002 22 0 0 0 4.51E+07 2.69E+07 - - - 9.9074 0.9999 221125_WJC_METTL3_EV_vs_WT_F10.14247.14247.3 7.95E-05 Aug-60 K.KAADHLKPFLDDSTLR.F sp|O43395|PRPF3_HUMAN 1 1825.9686 3.58 144998 14247 3 1825.966783 609.6635 U4\U6 small nuclear ribonucleoprotein Prp3 OS=Homo sapiens OX=9606 GN=PRPF3 PE=1 SV=2 6.75 2661.5 - 156246 - - - -1.0208 - 1.895 0.478 - 54.4 1 2 0 -0.0019 16 0 0 0 3.15E+06 8.79E+05 - - - 5.5089 0.9993 221125_WJC_METTL3_EV_vs_WT_F10.14256.14256.4 0.00308 11/120 K.QQEQLHLQLLTQQQAGKPQPK.E "sp|Q8IVH2|FOXP4_HUMAN,tr|B7ZBM3|B7ZBM3_HUMAN" 2 2440.3187 3.74 145000 14256 4 2440.323594 611.0869 Forkhead box protein P4 OS=Homo sapiens OX=9606 GN=FOXP4 PE=1 SV=1 8.6 2662.6 - 357644 - - - 2.0235 - 1.982 0.338 - 76 1 2 0 0.0049 21 0 0 0 6.08E+07 1.62E+07 - - - 2.3928 0.9987 221125_WJC_METTL3_EV_vs_WT_F10.14257.14257.3 0.0216 Jul-40 R.LLASTLVHSVK.K "sp|Q9NYF8|BCLF1_HUMAN,tr|E9PKI6|E9PKI6_HUMAN,tr|A0A1W2PQ43|A0A1W2PQ43_HUMAN,tr|E9PK91|E9PK91_HUMAN,tr|E9PJA7|E9PJA7_HUMAN,tr|E9PK09|E9PK09_HUMAN,tr|E9PQN2|E9PQN2_HUMAN" 7 1166.7023 1.6 145001 14257 3 1166.703327 389.908 Bcl-2-associated transcription factor 1 OS=Homo sapiens OX=9606 GN=BCLAF1 PE=1 SV=2 8.76 2662.8 - 131557 - - - 0.8725 - 1.522 0.306 - 36.5 1 2 0 0.001 11 0 0 0 9.97E+06 6.25E+06 - - - 3.1445 1 221125_WJC_METTL3_EV_vs_WT_F10.14258.14258.4 4.51E-09 15/126 K.SQEEPKDTFEHDPSESIDEFNK.S "sp|Q9NYF8|BCLF1_HUMAN,tr|E9PKI6|E9PKI6_HUMAN,tr|A0A1W2PQ43|A0A1W2PQ43_HUMAN,tr|E9PK91|E9PK91_HUMAN,tr|E9PJA7|E9PJA7_HUMAN,tr|E9PK09|E9PK09_HUMAN,tr|E9PQN2|E9PQN2_HUMAN" 7 2607.1249 2.47 145002 14258 4 2607.129902 652.7885 Bcl-2-associated transcription factor 1 OS=Homo sapiens OX=9606 GN=BCLAF1 PE=1 SV=2 4.12 2662.9 - 341420 - - - 1.924 - 2.76 0.643 - 105.2 1 2 1 0.005 22 0 0 0 9.06E+08 3.67E+08 - - - 5.1535 0.9993 221125_WJC_METTL3_EV_vs_WT_F10.14262.14262.4 0.000247 10/126 K.SQEEPK[136.11]DTFEHDPSESIDEFNK[136.11].S "sp|Q9NYF8|BCLF1_HUMAN,tr|E9PKI6|E9PKI6_HUMAN,tr|A0A1W2PQ43|A0A1W2PQ43_HUMAN,tr|E9PK91|E9PK91_HUMAN,tr|E9PJA7|E9PJA7_HUMAN,tr|E9PK09|E9PK09_HUMAN,tr|E9PQN2|E9PQN2_HUMAN" 7 2623.1533 2.47 145004 14262 4 2623.153064 656.7956 Bcl-2-associated transcription factor 1 OS=Homo sapiens OX=9606 GN=BCLAF1 PE=1 SV=2 4.12 2663.4 - 210504 - - - -0.0846 - 2.197 0.388 - 51.1 1 2 1 -0.0002 22 0 0 0 9.04E+08 3.66E+08 - - - 2.8606 0.9997 221125_WJC_METTL3_EV_vs_WT_F10.14263.14263.4 0.000673 11/102 K.LLNTVEETTKDVSGLHSK.L "sp|P52732|KIF11_HUMAN,tr|A0A7I2YQY4|A0A7I2YQY4_HUMAN,tr|A0A7I2V3A9|A0A7I2V3A9_HUMAN" 3 1970.032 3.92 145005 14263 4 1970.030636 493.5153 Kinesin-like protein KIF11 OS=Homo sapiens OX=9606 GN=KIF11 PE=1 SV=2 5.45 2663.6 - 193197 - - - -0.7106 - 1.904 0.463 - 74 1 2 1 -0.0014 18 0 0 0 5.83E+06 1.49E+06 - - - 3.4762 0.9077 221125_WJC_METTL3_EV_vs_WT_F10.14264.14264.4 1.54 9/138 R.LGYTHLYSSTQVSVRPLQHTQYER.F "sp|P39656|OST48_HUMAN,tr|A0A0C4DGS1|A0A0C4DGS1_HUMAN" 2 2862.4413 1.56 145006 14264 4 2862.442618 716.6176 Dolichyl-diphosphooligosaccharide--protein glycosyltransferase 48 kDa subunit OS=Homo sapiens OX=9606 GN=DDOST PE=1 SV=4 8.51 2663.7 - 150054 - - - 0.4639 - 1.651 0.118 - 43 1 2 0 0.0013 24 0 0 0 2.47E+06 1.59E+06 - - - 0.4136 0.9998 221125_WJC_METTL3_EV_vs_WT_F10.14265.14265.4 2.11E-05 10/138 R.LGYTHLYSSTQVSVR[166.11]PLQHTQYER[166.11].F "sp|P39656|OST48_HUMAN,tr|A0A0C4DGS1|A0A0C4DGS1_HUMAN" 2 2882.4578 1.56 145007 14265 4 2882.468213 721.6217 Dolichyl-diphosphooligosaccharide--protein glycosyltransferase 48 kDa subunit OS=Homo sapiens OX=9606 GN=DDOST PE=1 SV=4 8.51 2663.8 - 125239 - - - 3.6021 - 2.339 0.48 - 56.1 1 2 0 0.0104 24 0 0 0 2.47E+06 1.59E+06 - - - 3.6738 0.9998 221125_WJC_METTL3_EV_vs_WT_F10.14268.14268.4 0.000902 24/180 K.VTTAAAAAATSQDPEQHLTELREPAPGTNQR.Q sp|Q9UBW8|CSN7A_HUMAN 1 3230.5916 1.3 145008 14268 4 3230.596101 808.6552 COP9 signalosome complex subunit 7a OS=Homo sapiens OX=9606 GN=COPS7A PE=1 SV=1 4.83 2664.2 - 377858 - - - 1.3945 - 4.034 0.452 - 212.2 1 2 1 0.0045 31 0 0 0 1.53E+07 1.18E+07 - - - 3.5829 0.9998 221125_WJC_METTL3_EV_vs_WT_F10.14269.14269.4 5.96E-10 26/180 K.VTTAAAAAATSQDPEQHLTELR[166.11]EPAPGTNQR[166.11].Q sp|Q9UBW8|CSN7A_HUMAN 1 3250.6081 1.29 145009 14269 4 3250.615411 813.6593 COP9 signalosome complex subunit 7a OS=Homo sapiens OX=9606 GN=COPS7A PE=1 SV=1 4.83 2664.4 - 373013 - - - 2.238 - 4.518 0.516 - 240.6 1 2 1 0.0073 31 0 0 0 1.52E+07 1.18E+07 - - - 4.1736 0.9147 221125_WJC_METTL3_EV_vs_WT_F10.14284.14284.4 0.013 11/120 K.QQEQLHLQLLTQQQAGK[136.11]PQPK[136.11].E "sp|Q8IVH2|FOXP4_HUMAN,tr|B7ZBM3|B7ZBM3_HUMAN" 2 2456.3471 3.74 145016 14284 4 2456.365058 615.094 Forkhead box protein P4 OS=Homo sapiens OX=9606 GN=FOXP4 PE=1 SV=1 8.6 2666.5 - 483260 - - - 7.3288 - 2.034 0.274 - 74.2 1 2 0 0.018 21 0 0 0 6.08E+07 1.62E+07 - - - 1.8407 0.9099 221125_WJC_METTL3_EV_vs_WT_F10.14286.14286.4 0.00327 10/102 R.HSNLMLEDLDKSQEEIKK.H "sp|P11171|EPB41_HUMAN,tr|A0A2R8Y420|A0A2R8Y420_HUMAN,tr|A0A2R8YCW8|A0A2R8YCW8_HUMAN,tr|A0A2R8Y5C8|A0A2R8Y5C8_HUMAN,tr|A0A2R8Y5G2|A0A2R8Y5G2_HUMAN,tr|A0A2R8Y5Z6|A0A2R8Y5Z6_HUMAN,tr|A0A2R8YD30|A0A2R8YD30_HUMAN" 7 2156.0783 0.82 145017 14286 4 2156.092897 540.0269 Protein 4.1 OS=Homo sapiens OX=9606 GN=EPB41 PE=1 SV=4 4.9 2666.7 - 212284 - - - 6.7544 - 2.101 0.322 - 67.9 1 2 1 0.0146 18 0 0 0 2.92E+06 3.58E+06 - - - 2.279 1 221125_WJC_METTL3_EV_vs_WT_F10.14294.14294.3 3.14E-09 19/84 K.SQEEPKDTFEHDPSESIDEFNK.S "sp|Q9NYF8|BCLF1_HUMAN,tr|E9PKI6|E9PKI6_HUMAN,tr|A0A1W2PQ43|A0A1W2PQ43_HUMAN,tr|E9PK91|E9PK91_HUMAN,tr|E9PJA7|E9PJA7_HUMAN,tr|E9PK09|E9PK09_HUMAN,tr|E9PQN2|E9PQN2_HUMAN" 7 2607.1249 2.84 145022 14294 3 2607.127373 870.0489 Bcl-2-associated transcription factor 1 OS=Homo sapiens OX=9606 GN=BCLAF1 PE=1 SV=2 4.12 2667.9 - 682865 - - - 0.9539 - 3.844 0.597 - 333.3 1 2 1 0.0025 22 0 0 0 2.12E+08 7.49E+07 - - - 8.3876 0.8834 221125_WJC_METTL3_EV_vs_WT_F10.14296.14296.4 1.41E-06 18/144 A.SESSGIPERPC[160.03]VLTGTPESIEQAKR.L sp|Q96I24|FUBP3_HUMAN 1 2727.3498 2.48 145023 14296 4 2727.366107 682.8447 Far upstream element-binding protein 3 OS=Homo sapiens OX=9606 GN=FUBP3 PE=1 SV=2 4.94 2668.1 - 837498 - - - 5.9945 - 2.958 0.484 - 162.1 1 1 0 0.0163 25 0 0 0 4.33E+07 1.75E+07 - - - 3.7792 1 221125_WJC_METTL3_EV_vs_WT_F10.14305.14305.3 1.16E-07 21/84 K.SQEEPK[136.11]DTFEHDPSESIDEFNK[136.11].S "sp|Q9NYF8|BCLF1_HUMAN,tr|E9PKI6|E9PKI6_HUMAN,tr|A0A1W2PQ43|A0A1W2PQ43_HUMAN,tr|E9PK91|E9PK91_HUMAN,tr|E9PJA7|E9PJA7_HUMAN,tr|E9PK09|E9PK09_HUMAN,tr|E9PQN2|E9PQN2_HUMAN" 7 2623.1533 2.84 145027 14305 3 2623.156722 875.3917 Bcl-2-associated transcription factor 1 OS=Homo sapiens OX=9606 GN=BCLAF1 PE=1 SV=2 4.12 2669.5 - 551207 - - - 1.3099 - 3.935 0.64 - 469.3 1 2 1 0.0034 22 0 0 0 2.12E+08 7.49E+07 - - - 8.9222 0.9997 221125_WJC_METTL3_EV_vs_WT_F10.14307.14307.4 4.42E-10 18/108 K.SKEIENGHIFTVNDQFTSK.L "sp|Q13618|CUL3_HUMAN,tr|A0A087WTG3|A0A087WTG3_HUMAN" 2 2193.0702 1.27 145029 14307 4 2193.077683 549.2748 Cullin-3 OS=Homo sapiens OX=9606 GN=CUL3 PE=1 SV=2 5.42 2669.7 - 568527 - - - 3.4066 - 3.624 0.551 - 317.1 1 2 1 0.0075 19 0 0 0 3.00E+07 2.36E+07 - - - 4.4554 0.9881 221125_WJC_METTL3_EV_vs_WT_F10.14312.14312.3 0.000602 Nov-88 R.QNSQLPAQVQNGPSQEELEIQRR.Q "sp|Q8N8S7|ENAH_HUMAN,tr|A0A0U1RQP7|A0A0U1RQP7_HUMAN,tr|A0A075B6E5|A0A075B6E5_HUMAN,tr|A0A0U1RRM6|A0A0U1RRM6_HUMAN" 4 2648.3267 0.95 145032 14312 3 2648.335748 883.7828 Protein enabled homolog OS=Homo sapiens OX=9606 GN=ENAH PE=1 SV=2 4.79 2670.5 - 220095 - - - 3.4335 - 1.916 0.24 - 65 1 2 0 0.0091 23 0 0 0 6.47E+06 6.78E+06 - - - 2.7387 0.9998 221125_WJC_METTL3_EV_vs_WT_F10.14313.14313.3 0.000668 Nov-88 R.QNSQLPAQVQNGPSQEELEIQR[166.11]R[166.11].Q "sp|Q8N8S7|ENAH_HUMAN,tr|A0A0U1RQP7|A0A0U1RQP7_HUMAN,tr|A0A075B6E5|A0A075B6E5_HUMAN,tr|A0A0U1RRM6|A0A0U1RRM6_HUMAN" 4 2668.3432 0.95 145033 14313 3 2668.342452 890.455 Protein enabled homolog OS=Homo sapiens OX=9606 GN=ENAH PE=1 SV=2 4.79 2670.7 - 182060 - - - -0.2784 - 1.9 0.4 - 69.5 1 2 0 -0.0007 23 0 0 0 6.47E+06 6.78E+06 - - - 4.5052 1 221125_WJC_METTL3_EV_vs_WT_F10.14316.14316.3 1.20E-11 17/72 K.SKEIENGHIFTVNDQFTSK.L "sp|Q13618|CUL3_HUMAN,tr|A0A087WTG3|A0A087WTG3_HUMAN" 2 2193.0702 0.79 145036 14316 3 2193.070786 732.0307 Cullin-3 OS=Homo sapiens OX=9606 GN=CUL3 PE=1 SV=2 5.42 2671.1 - 305698 - - - 0.2617 - 3.734 0.639 - 418.7 1 2 1 0.0006 19 0 0 0 1.17E+07 1.48E+07 - - - 8.9008 0.9997 221125_WJC_METTL3_EV_vs_WT_F10.14319.14319.4 0.000386 18/108 K.SK[136.11]EIENGHIFTVNDQFTSK[136.11].L "sp|Q13618|CUL3_HUMAN,tr|A0A087WTG3|A0A087WTG3_HUMAN" 2 2209.0986 1.13 145037 14319 4 2209.099059 553.2819 Cullin-3 OS=Homo sapiens OX=9606 GN=CUL3 PE=1 SV=2 5.42 2671.5 - 545540 - - - 0.2023 - 3.273 0.441 - 362.7 1 2 1 0.0004 19 0 0 0 3.04E+07 2.69E+07 - - - 3.4654 1 221125_WJC_METTL3_EV_vs_WT_F10.14320.14320.3 1.33E-06 14/104 R.ASHSANSQPSATTVTAITPAPIQQPVK.S sp|O95835|LATS1_HUMAN 1 2701.4035 2.64 145038 14320 3 2701.40744 901.4751 Serine\threonine-protein kinase LATS1 OS=Homo sapiens OX=9606 GN=LATS1 PE=1 SV=1 8.8 2671.6 - 260837 - - - 1.4555 - 2.757 0.581 - 104.1 1 2 0 0.0039 27 0 0 0 2.22E+07 8.41E+06 - - - 7.3497 0.9999 221125_WJC_METTL3_EV_vs_WT_F10.14330.14330.3 2.37E-06 21/76 K.SAVADK[136.11]HELLSLASSNHLGK[136.11].N "sp|O15372|EIF3H_HUMAN,tr|B3KS98|B3KS98_HUMAN,tr|A0A087WZK9|A0A087WZK9_HUMAN,tr|E5RJT0|E5RJT0_HUMAN" 4 2092.1248 2.23 145044 14330 3 2092.124154 698.3822 Eukaryotic translation initiation factor 3 subunit H OS=Homo sapiens OX=9606 GN=EIF3H PE=1 SV=1 6.66 2672.8 - 1.72E+06 - - - -0.293 - 3.574 0.571 - 407.5 1 2 1 -0.0006 20 0 0 0 1.01E+08 4.54E+07 - - - 7.9959 0.9851 221125_WJC_METTL3_EV_vs_WT_F10.14335.14335.3 0.000622 Nov-64 S.TASAVPELATDPELEK[136.11]K[136.11].L "sp|Q86U44|MTA70_HUMAN,tr|B4E349|B4E349_HUMAN,tr|F5H6D8|F5H6D8_HUMAN,tr|H0YFV6|H0YFV6_HUMAN,tr|B4DTN4|B4DTN4_HUMAN" 5 1813.9644 0.06 145046 14335 3 1813.960302 605.6621 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 4.41 2673.5 - 275591 - - - -2.2647 - 2.515 0.425 - 114.6 1 1 0 -0.0041 17 0 0 0 2.38E+06 3.96E+07 - - - 5.6071 1 221125_WJC_METTL3_EV_vs_WT_F10.14336.14336.3 8.00E-08 9/104 R.ASHSANSQPSATTVTAITPAPIQQPVK[136.11].S sp|O95835|LATS1_HUMAN 1 2709.4177 2.64 145047 14336 3 2709.41834 904.1465 Serine\threonine-protein kinase LATS1 OS=Homo sapiens OX=9606 GN=LATS1 PE=1 SV=1 8.8 2673.7 - 173860 - - - 0.2333 - 2.208 0.573 - 43.8 1 2 0 0.0006 27 0 0 0 2.22E+07 8.41E+06 - - - 6.7505 0.9894 221125_WJC_METTL3_EV_vs_WT_F10.14347.14347.4 0.0154 Oct-84 K.NK[136.11]LDFLR[166.11]PYTVPNK[136.11]K[136.11].G sp|Q99436|PSB7_HUMAN 1 1866.0817 0.53 145052 14347 4 1866.082647 467.5277 Proteasome subunit beta type-7 OS=Homo sapiens OX=9606 GN=PSMB7 PE=1 SV=1 10 2675.1 - 243617 - - - 0.4946 - 1.664 0.258 - 82.8 1 2 1 0.0009 15 0 0 0 3.58E+06 6.77E+06 - - - 1.6536 0.9999 221125_WJC_METTL3_EV_vs_WT_F10.14362.14362.3 9.97E-07 6/100 R.C[160.03]GPTHQGSEDPSMLSQAQSATEVEER[166.11].H "sp|Q9BVS5|TR61B_HUMAN,tr|F8WDR2|F8WDR2_HUMAN" 2 2840.2217 0.001 145062 14362 3 2840.222544 947.7478 "tRNA (adenine(58)-N(1))-methyltransferase, mitochondrial OS=Homo sapiens OX=9606 GN=TRMT61B PE=1 SV=2" 4.25 2677.1 - 132221 - - - 0.3074 - 1.612 0.532 - 27.3 1 2 0 0.0009 26 0 0 0 0.00E+00 4.65E+05 - - - 5.5695 1 221125_WJC_METTL3_EV_vs_WT_F10.14364.14364.3 9.08E-16 25/112 R.VPSAAC[160.03]PPFPPHGAPVSASSSSSSPGGSR.G sp|Q9H7S9|ZN703_HUMAN 1 2734.2769 2.8 145063 14364 3 2734.276737 912.4329 Zinc finger protein 703 OS=Homo sapiens OX=9606 GN=ZNF703 PE=1 SV=1 8.23 2677.4 - 557586 - - - -0.0695 - 4.661 0.723 - 345.7 1 2 0 -0.0002 29 0 0 0 2.35E+07 8.39E+06 - - - 10.1419 1 221125_WJC_METTL3_EV_vs_WT_F10.14370.14370.2 1.11E-13 15/38 R.FSSC[160.03]GGGGGSFGAGGGFGSR.S sp|P04264|K2C1_HUMAN 1 1764.7274 999 145067 14370 2 1764.72389 883.371 "Keratin, type II cytoskeletal 1 OS=Homo sapiens OX=9606 GN=KRT1 PE=1 SV=6" 8.25 2678.2 - 236429 - - - -2.0065 - 3.503 0.759 - 603.8 1 2 0 -0.0035 20 0 0 0 3.94E+06 0.00E+00 - - - 7.7279 0.9983 221125_WJC_METTL3_EV_vs_WT_F10.14375.14375.3 0.0208 Jul-36 R.K[136.11]QDSGHLDLR[166.11].N "sp|Q86U44|MTA70_HUMAN,tr|B4E349|B4E349_HUMAN,tr|F5H6D8|F5H6D8_HUMAN,tr|B4DTN4|B4DTN4_HUMAN" 4 1185.6221 0.01 145069 14375 3 1185.623649 396.2146 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 6.75 2678.9 - 84789.8 - - - 1.3023 - 1.439 0.315 - 79.3 1 2 0 0.0015 10 0 0 0 4.41E+04 7.94E+06 - - - 3.1144 0.9999 221125_WJC_METTL3_EV_vs_WT_F10.14381.14381.4 1.65E-08 19/114 K.SAVADKHELLSLASSNHLGK.N "sp|O15372|EIF3H_HUMAN,tr|B3KS98|B3KS98_HUMAN,tr|A0A087WZK9|A0A087WZK9_HUMAN,tr|E5RJT0|E5RJT0_HUMAN" 4 2076.0964 1.87 145071 14381 4 2076.100151 520.0314 Eukaryotic translation initiation factor 3 subunit H OS=Homo sapiens OX=9606 GN=EIF3H PE=1 SV=1 6.66 2679.7 - 5.35E+06 - - - 1.8227 - 3.991 0.53 - 273.2 1 2 1 0.0038 20 0 0 0 5.71E+08 3.05E+08 - - - 4.3008 1 221125_WJC_METTL3_EV_vs_WT_F10.14391.14391.3 1.10E-11 22/104 K.TNHIGHTGYLNTVTVSPDGSLC[160.03]ASGGK[136.11].D "sp|P63244|RACK1_HUMAN,tr|H0YAM7|H0YAM7_HUMAN,tr|D6RFX4|D6RFX4_HUMAN,tr|D6R9Z1|D6R9Z1_HUMAN,tr|J3KPE3|J3KPE3_HUMAN,tr|D6R9L0|D6R9L0_HUMAN,tr|D6RHH4|D6RHH4_HUMAN,tr|D6RAC2|D6RAC2_HUMAN,tr|H0Y8R5|H0Y8R5_HUMAN,tr|D6REE5|D6REE5_HUMAN,tr|H0Y8W2|H0Y8W2_HUMAN" 11 2750.3173 0.67 145077 14391 3 2750.310175 917.7797 Receptor of activated protein C kinase 1 OS=Homo sapiens OX=9606 GN=RACK1 PE=1 SV=3 6.61 2680.9 - 338608 - - - -2.6059 - 4.011 0.683 - 428 1 2 0 -0.0072 27 0 0 0 2.49E+07 3.72E+07 - - - 9.3485 1 221125_WJC_METTL3_EV_vs_WT_F10.14404.14404.3 3.37E-10 22/104 K.TNHIGHTGYLNTVTVSPDGSLC[160.03]ASGGK.D "sp|P63244|RACK1_HUMAN,tr|H0YAM7|H0YAM7_HUMAN,tr|D6RFX4|D6RFX4_HUMAN,tr|D6R9Z1|D6R9Z1_HUMAN,tr|J3KPE3|J3KPE3_HUMAN,tr|D6R9L0|D6R9L0_HUMAN,tr|D6RHH4|D6RHH4_HUMAN,tr|D6RAC2|D6RAC2_HUMAN,tr|H0Y8R5|H0Y8R5_HUMAN,tr|D6REE5|D6REE5_HUMAN,tr|H0Y8W2|H0Y8W2_HUMAN" 11 2742.3031 0.69 145084 14404 3 2742.309469 915.1083 Receptor of activated protein C kinase 1 OS=Homo sapiens OX=9606 GN=RACK1 PE=1 SV=3 6.61 2682.7 - 445683 - - - 2.3072 - 3.82 0.596 - 488.6 1 2 0 0.0063 27 0 0 0 2.61E+07 3.80E+07 - - - 8.2665 0.9996 221125_WJC_METTL3_EV_vs_WT_F10.14405.14405.2 0.000195 16-Oct K.VGLQVVAVK.A "sp|P10809|CH60_HUMAN,tr|A0A7I2V2X6|A0A7I2V2X6_HUMAN,tr|A0A7I2YQK6|A0A7I2YQK6_HUMAN,tr|A0A7I2V599|A0A7I2V599_HUMAN,tr|A0A7I2V5M1|A0A7I2V5M1_HUMAN" 5 911.5804 1.2 145085 14405 2 911.580842 456.7975 "60 kDa heat shock protein, mitochondrial OS=Homo sapiens OX=9606 GN=HSPD1 PE=1 SV=2" 8.72 2682.8 - 269337 - - - 0.4816 - 1.984 0.307 - 232.6 1 2 0 0.0004 9 0 0 0 7.98E+06 6.66E+06 - - - 3.2904 1 221125_WJC_METTL3_EV_vs_WT_F10.14409.14409.3 1.02E-08 17/116 R.IEVQDTSGGTTALR[166.11]PSASTQALSSSVSSSK[136.11].L "sp|Q16531|DDB1_HUMAN,tr|A0A7P0TAK7|A0A7P0TAK7_HUMAN,tr|A0A7P0T870|A0A7P0T870_HUMAN,tr|A0A7P0TB30|A0A7P0TB30_HUMAN,tr|A0A7P0Z3Z5|A0A7P0Z3Z5_HUMAN,tr|F5GY55|F5GY55_HUMAN,tr|A0A7P0Z4B9|A0A7P0Z4B9_HUMAN,tr|A0A7P0T965|A0A7P0T965_HUMAN" 8 2969.4908 0.65 145086 14409 3 2969.49964 990.8376 DNA damage-binding protein 1 OS=Homo sapiens OX=9606 GN=DDB1 PE=1 SV=1 6.07 2683.4 - 198842 - - - 2.9692 - 3.196 0.63 - 175.7 1 2 0 0.0088 30 0 0 0 4.83E+07 7.45E+07 - - - 8.2345 1 221125_WJC_METTL3_EV_vs_WT_F10.14424.14424.3 1.04E-10 24/116 R.IEVQDTSGGTTALRPSASTQALSSSVSSSK.L "sp|Q16531|DDB1_HUMAN,tr|A0A7P0TAK7|A0A7P0TAK7_HUMAN,tr|A0A7P0T870|A0A7P0T870_HUMAN,tr|A0A7P0TB30|A0A7P0TB30_HUMAN,tr|A0A7P0Z3Z5|A0A7P0Z3Z5_HUMAN,tr|F5GY55|F5GY55_HUMAN,tr|A0A7P0Z4B9|A0A7P0Z4B9_HUMAN,tr|A0A7P0T965|A0A7P0T965_HUMAN" 8 2951.4684 0.65 145092 14424 3 2951.475488 984.8301 DNA damage-binding protein 1 OS=Homo sapiens OX=9606 GN=DDB1 PE=1 SV=1 6.07 2685.6 - 339326 - - - 2.4174 - 3.901 0.662 - 369.6 1 2 0 0.0071 30 0 0 0 4.83E+07 7.45E+07 - - - 9.0504 1 221125_WJC_METTL3_EV_vs_WT_F10.14437.14437.4 9.35E-12 32/156 K.TNHIGHTGYLNTVTVSPDGSLC[160.03]ASGGK.D "sp|P63244|RACK1_HUMAN,tr|H0YAM7|H0YAM7_HUMAN,tr|D6RFX4|D6RFX4_HUMAN,tr|D6R9Z1|D6R9Z1_HUMAN,tr|J3KPE3|J3KPE3_HUMAN,tr|D6R9L0|D6R9L0_HUMAN,tr|D6RHH4|D6RHH4_HUMAN,tr|D6RAC2|D6RAC2_HUMAN,tr|H0Y8R5|H0Y8R5_HUMAN,tr|D6REE5|D6REE5_HUMAN,tr|H0Y8W2|H0Y8W2_HUMAN" 11 2742.3031 1.17 145098 14437 4 2742.309598 686.5831 Receptor of activated protein C kinase 1 OS=Homo sapiens OX=9606 GN=RACK1 PE=1 SV=3 6.61 2687.3 - 5.19E+06 - - - 2.3542 - 5.438 0.585 - 827.4 1 2 0 0.0065 27 0 0 0 1.98E+08 1.70E+08 - - - 4.8459 1 221125_WJC_METTL3_EV_vs_WT_F10.14439.14439.4 2.03E-08 17/108 R.RPGQSFHVNSEVNSVLSPR.S "sp|Q14671|PUM1_HUMAN,tr|Q5T1Z8|Q5T1Z8_HUMAN,tr|H0YEH2|H0YEH2_HUMAN,tr|Q5T1Z4|Q5T1Z4_HUMAN" 4 2109.0715 1.04 145099 14439 4 2109.074039 528.2752 Pumilio homolog 1 OS=Homo sapiens OX=9606 GN=PUM1 PE=1 SV=3 9.61 2687.5 - 239911 - - - 1.1806 - 3.598 0.579 - 226.5 1 2 0 0.0025 19 0 0 0 2.26E+07 2.18E+07 - - - 4.6981 1 221125_WJC_METTL3_EV_vs_WT_F10.14445.14445.4 9.14E-06 19/114 R.K[136.11]PTDGASSSNC[160.03]VTDISHLVR[166.11].K "sp|P49321|NASP_HUMAN,tr|H0YDS9|H0YDS9_HUMAN,tr|Q5T624|Q5T624_HUMAN" 3 2161.0553 0.42 145103 14445 4 2161.059409 541.2711 Nuclear autoantigenic sperm protein OS=Homo sapiens OX=9606 GN=NASP PE=1 SV=2 6.74 2688.3 - 214344 - - - 1.9241 - 3.733 0.641 - 375.3 1 2 0 0.0042 20 0 0 0 2.72E+07 6.43E+07 - - - 5.2445 1 221125_WJC_METTL3_EV_vs_WT_F10.14450.14450.3 2.55E-12 17/76 R.K[136.11]PTDGASSSNC[160.03]VTDISHLVR[166.11].K "sp|P49321|NASP_HUMAN,tr|H0YDS9|H0YDS9_HUMAN,tr|Q5T624|Q5T624_HUMAN" 3 2161.0553 0.54 145106 14450 3 2161.053557 721.359 Nuclear autoantigenic sperm protein OS=Homo sapiens OX=9606 GN=NASP PE=1 SV=2 6.74 2689 - 207442 - - - -0.7839 - 3.638 0.645 - 309.3 1 2 0 -0.0017 20 0 0 0 2.21E+07 4.12E+07 - - - 8.8637 0.9998 221125_WJC_METTL3_EV_vs_WT_F10.14451.14451.4 1.22E-06 14/174 R.IEVQDTSGGTTALRPSASTQALSSSVSSSK.L "sp|Q16531|DDB1_HUMAN,tr|A0A7P0TAK7|A0A7P0TAK7_HUMAN,tr|A0A7P0T870|A0A7P0T870_HUMAN,tr|A0A7P0TB30|A0A7P0TB30_HUMAN,tr|A0A7P0Z3Z5|A0A7P0Z3Z5_HUMAN,tr|F5GY55|F5GY55_HUMAN,tr|A0A7P0Z4B9|A0A7P0Z4B9_HUMAN,tr|A0A7P0T965|A0A7P0T965_HUMAN" 8 2951.4684 0.12 145107 14451 4 2951.467368 738.8744 DNA damage-binding protein 1 OS=Homo sapiens OX=9606 GN=DDB1 PE=1 SV=1 6.07 2689.1 - 415261 - - - -0.3337 - 2.682 0.386 - 78 1 2 0 -0.001 30 0 0 0 1.20E+07 9.70E+07 - - - 2.8874 0.9347 221125_WJC_METTL3_EV_vs_WT_F10.14466.14466.3 0.615 Jul-60 K.NQVALNPQNTVFDAK[136.11]R[166.11].L "sp|P0DMV8|HS71A_HUMAN,sp|P0DMV9|HS71B_HUMAN,tr|A0A0G2JIW1|A0A0G2JIW1_HUMAN" 3 1831.966 1.25 145117 14466 3 1831.968645 611.6626 Heat shock 70 kDa protein 1A OS=Homo sapiens OX=9606 GN=HSPA1A PE=1 SV=1 8.75 2690.9 - 68563.3 - - - 1.4629 - 1.173 0.174 - 30 1 2 0 0.0027 16 0 0 0 6.00E+06 4.82E+06 - - - 0.8886 1 221125_WJC_METTL3_EV_vs_WT_F10.14478.14478.3 2.86E-11 17/84 K.DHTPSQELALTQSVGGDSSADR[166.11].L "sp|Q86U44|MTA70_HUMAN,tr|H0YFV6|H0YFV6_HUMAN" 2 2280.0494 0.01 145123 14478 3 2280.039257 761.0237 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 4.22 2692.4 - 479584 - - - -4.4341 - 3.457 0.656 - 271.3 1 2 0 -0.0101 22 0 0 0 8.81E+04 1.71E+07 - - - 8.7917 1 221125_WJC_METTL3_EV_vs_WT_F10.14479.14479.3 3.36E-12 19/76 R.KPTDGASSSNC[160.03]VTDISHLVR.K "sp|P49321|NASP_HUMAN,tr|H0YDS9|H0YDS9_HUMAN,tr|Q5T624|Q5T624_HUMAN" 3 2143.0328 0.53 145124 14479 3 2143.034939 715.3515 Nuclear autoantigenic sperm protein OS=Homo sapiens OX=9606 GN=NASP PE=1 SV=2 6.74 2692.6 - 349061 - - - 1.007 - 3.853 0.664 - 327.2 1 2 0 0.0022 20 0 0 0 2.20E+07 4.12E+07 - - - 9.2147 0.9999 221125_WJC_METTL3_EV_vs_WT_F10.14483.14483.4 9.17E-13 24/126 K.SQEEPKDTFEHDPSESIDEFNK.S "sp|Q9NYF8|BCLF1_HUMAN,tr|E9PKI6|E9PKI6_HUMAN,tr|A0A1W2PQ43|A0A1W2PQ43_HUMAN,tr|E9PK91|E9PK91_HUMAN,tr|E9PJA7|E9PJA7_HUMAN,tr|E9PK09|E9PK09_HUMAN,tr|E9PQN2|E9PQN2_HUMAN" 7 2607.1249 2.47 145126 14483 4 2607.128672 652.7885 Bcl-2-associated transcription factor 1 OS=Homo sapiens OX=9606 GN=BCLAF1 PE=1 SV=2 4.12 2693.1 - 3.13E+06 - - - 1.4522 - 4.237 0.569 - 375.3 1 2 1 0.0038 22 0 0 0 9.06E+08 3.66E+08 - - - 4.65 0.9999 221125_WJC_METTL3_EV_vs_WT_F10.14488.14488.4 4.08E-12 21/126 K.SQEEPK[136.11]DTFEHDPSESIDEFNK[136.11].S "sp|Q9NYF8|BCLF1_HUMAN,tr|E9PKI6|E9PKI6_HUMAN,tr|A0A1W2PQ43|A0A1W2PQ43_HUMAN,tr|E9PK91|E9PK91_HUMAN,tr|E9PJA7|E9PJA7_HUMAN,tr|E9PK09|E9PK09_HUMAN,tr|E9PQN2|E9PQN2_HUMAN" 7 2623.1533 2.47 145129 14488 4 2623.154869 656.7956 Bcl-2-associated transcription factor 1 OS=Homo sapiens OX=9606 GN=BCLAF1 PE=1 SV=2 4.12 2693.7 - 1.17E+06 - - - 0.6035 - 3.943 0.519 - 251.9 1 2 1 0.0016 22 0 0 0 9.04E+08 3.66E+08 - - - 4.1918 1 221125_WJC_METTL3_EV_vs_WT_F10.14495.14495.4 5.81E-07 15/120 R.FSPANYDQAHLHPHLFSDQSR.G "sp|Q9Y2K2|SIK3_HUMAN,tr|H0Y4E8|H0Y4E8_HUMAN" 2 2466.1465 4.62 145133 14495 4 2466.148978 617.5439 Serine\threonine-protein kinase SIK3 OS=Homo sapiens OX=9606 GN=SIK3 PE=1 SV=4 6.26 2694.6 - 299931 - - - 1.0028 - 2.988 0.571 - 174.2 1 2 0 0.0025 21 0 0 0 6.88E+06 1.49E+06 - - - 4.5572 1 221125_WJC_METTL3_EV_vs_WT_F10.14503.14503.4 3.33E-14 23/168 K.RPFAVTTQSFGSNAEGQHSGFGPQPNPEK.V "sp|Q96PV6|LENG8_HUMAN,tr|A0A0G2JNN3|A0A0G2JNN3_HUMAN,tr|E7EWC7|E7EWC7_HUMAN,tr|C9JMY0|C9JMY0_HUMAN,tr|A0A087WUE4|A0A087WUE4_HUMAN" 5 3071.4486 1.09 145136 14503 4 3071.452432 768.8694 Leukocyte receptor cluster member 8 OS=Homo sapiens OX=9606 GN=LENG8 PE=1 SV=3 6.76 2695.6 - 352386 - - - 1.2603 - 4.528 0.725 - 320.6 1 2 0 0.0039 29 0 0 0 1.09E+07 1.01E+07 - - - 6.0008 1 221125_WJC_METTL3_EV_vs_WT_F10.14506.14506.4 1.43E-09 20/168 K.R[166.11]PFAVTTQSFGSNAEGQHSGFGPQPNPEK[136.11].V "sp|Q96PV6|LENG8_HUMAN,tr|A0A0G2JNN3|A0A0G2JNN3_HUMAN,tr|E7EWC7|E7EWC7_HUMAN,tr|C9JMY0|C9JMY0_HUMAN,tr|A0A087WUE4|A0A087WUE4_HUMAN" 5 3089.471 1.08 145139 14506 4 3089.466396 773.375 Leukocyte receptor cluster member 8 OS=Homo sapiens OX=9606 GN=LENG8 PE=1 SV=3 6.76 2696 - 418077 - - - -1.5003 - 3.71 0.58 - 197.1 1 2 0 -0.0046 29 0 0 0 1.13E+07 1.05E+07 - - - 4.6771 0.9999 221125_WJC_METTL3_EV_vs_WT_F10.14516.14516.4 9.84E-06 18/108 R.SQELHLRPESHSYLPELGK.S "sp|Q9Y618|NCOR2_HUMAN,tr|C9JQE8|C9JQE8_HUMAN,tr|C9JE98|C9JE98_HUMAN,tr|H0YGK8|H0YGK8_HUMAN,tr|C9J330|C9J330_HUMAN,tr|C9J0Q5|C9J0Q5_HUMAN" 6 2219.1335 1.44 145143 14516 4 2219.13566 555.7906 Nuclear receptor corepressor 2 OS=Homo sapiens OX=9606 GN=NCOR2 PE=1 SV=3 5.97 2697.4 - 838389 - - - 0.9819 - 3.342 0.443 - 200.2 1 2 0 0.0022 19 0 0 0 1.68E+07 1.16E+07 - - - 3.4894 0.7827 221125_WJC_METTL3_EV_vs_WT_F10.14518.14518.4 0.0331 11/174 P.VPTAPTSGGPK[136.11]PSTASAVPELATDPELEK[136.11]K[136.11].L "sp|Q86U44|MTA70_HUMAN,tr|B4E349|B4E349_HUMAN,tr|F5H6D8|F5H6D8_HUMAN,tr|H0YFV6|H0YFV6_HUMAN,tr|B4DTN4|B4DTN4_HUMAN" 5 2998.5925 0.001 145144 14518 4 2998.593942 750.6554 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 4.87 2697.6 - 382639 - - - 0.4816 - 2.189 0.258 - 33.4 1 1 0 0.0014 30 0 0 0 0.00E+00 2.65E+08 - - - 1.711 0.9999 221125_WJC_METTL3_EV_vs_WT_F10.14519.14519.3 5.71E-06 8/100 R.YSQGDDDGSSSSGGSSVAGSQSTLFK.D "sp|Q9UH99|SUN2_HUMAN,tr|B0QY65|B0QY65_HUMAN,tr|B0QY69|B0QY69_HUMAN,tr|B0QY64|B0QY64_HUMAN,tr|B0QY67|B0QY67_HUMAN,tr|B0QY66|B0QY66_HUMAN,tr|B0QY63|B0QY63_HUMAN,tr|B0QY68|B0QY68_HUMAN" 8 2510.0681 9.21 145145 14519 3 2510.069165 837.6966 SUN domain-containing protein 2 OS=Homo sapiens OX=9606 GN=SUN2 PE=1 SV=3 3.93 2697.7 - 331575 - - - 0.4247 - 1.731 0.512 - 42.2 1 2 0 0.0011 26 0 0 0 5.87E+06 6.37E+05 - - - 5.5104 1 221125_WJC_METTL3_EV_vs_WT_F10.14521.14521.4 8.55E-15 27/132 R.KVTFFEPGSGDENGTSNKEDEFR.M "sp|O95793|STAU1_HUMAN,tr|Q5JW30|Q5JW30_HUMAN" 2 2589.1619 2.44 145147 14521 4 2589.158321 648.2978 Double-stranded RNA-binding protein Staufen homolog 1 OS=Homo sapiens OX=9606 GN=STAU1 PE=1 SV=2 4.36 2698 - 411488 - - - -1.3977 - 5.245 0.653 - 885.4 1 2 1 -0.0036 23 0 0 0 9.26E+07 3.79E+07 - - - 5.4456 1 221125_WJC_METTL3_EV_vs_WT_F10.14527.14527.4 3.53E-06 18/114 K.R[166.11]GLLQDDAHPTLVTYADHSK[136.11].L "sp|Q86U44|MTA70_HUMAN,tr|F5H6D8|F5H6D8_HUMAN,tr|H0YFV6|H0YFV6_HUMAN,tr|B4DTN4|B4DTN4_HUMAN" 4 2254.1461 0.01 145150 14527 4 2254.146242 564.5438 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 5.99 2698.7 - 895369 - - - 0.0563 - 3.261 0.485 - 298.6 1 2 0 0.0001 20 0 0 0 6.34E+05 7.47E+07 - - - 3.8426 1 221125_WJC_METTL3_EV_vs_WT_F10.14530.14530.2 1.18E-08 17/42 K.DHTPSQELALTQSVGGDSSADR[166.11].L "sp|Q86U44|MTA70_HUMAN,tr|H0YFV6|H0YFV6_HUMAN" 2 2280.0494 0.01 145153 14530 2 2281.043062 1141.032 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 4.22 2699.1 - 331391 - - - 435.8217 - 3.272 0.672 - 444.6 1 2 0 0.9937 22 0 0 0 2.34E+06 2.98E+08 - - - 6.6067 1 221125_WJC_METTL3_EV_vs_WT_F10.14534.14534.3 3.37E-09 17/68 K.YVHYEIDAC[160.03]MDSEAPGSK[136.11].D "sp|Q86U44|MTA70_HUMAN,tr|H0YFV6|H0YFV6_HUMAN" 2 2078.8805 0.02 145155 14534 3 2079.877754 693.9674 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 4.31 2699.7 - 6.38E+06 - - - 479.7111 - 3.501 0.698 - 320.5 1 2 0 0.9973 18 0 0 0 5.57E+06 2.94E+08 - - - 9.166 1 221125_WJC_METTL3_EV_vs_WT_F10.14541.14541.3 8.04E-11 27/84 K.DHTPSQELALTQSVGGDSSADR.L "sp|Q86U44|MTA70_HUMAN,tr|H0YFV6|H0YFV6_HUMAN" 2 2270.0411 0.04 145159 14541 3 2271.039534 757.6876 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 4.22 2700.5 - 2.30E+06 - - - 439.8321 - 4.643 0.648 - 816.3 1 2 0 0.9984 22 0 0 0 5.84E+08 1.52E+10 - - - 9.1281 0.9999 221125_WJC_METTL3_EV_vs_WT_F10.14546.14546.4 1.67E-10 23/132 M.VKETTYYDVLGVKPNATQEELKK.A sp|P31689|DNJA1_HUMAN 1 2652.401 0.45 145162 14546 4 2652.398941 664.1075 DnaJ homolog subfamily A member 1 OS=Homo sapiens OX=9606 GN=DNAJA1 PE=1 SV=2 6.22 2701.1 - 2.72E+06 - - - -0.7944 - 4.758 0.601 - 297.4 1 2 1 -0.0021 23 0 0 0 2.29E+08 5.05E+08 - - - 4.9619 0.9732 221125_WJC_METTL3_EV_vs_WT_F10.14547.14547.3 0.000228 Oct-68 P.STASAVPELATDPELEK[136.11]K[136.11].L "sp|Q86U44|MTA70_HUMAN,tr|B4E349|B4E349_HUMAN,tr|F5H6D8|F5H6D8_HUMAN,tr|H0YFV6|H0YFV6_HUMAN,tr|B4DTN4|B4DTN4_HUMAN" 5 1900.9964 0.001 145163 14547 3 1900.991237 634.6728 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 4.41 2701.2 - 625106 - - - -2.7359 - 2.173 0.438 - 95.7 1 1 0 -0.0052 18 0 0 0 0.00E+00 1.64E+08 - - - 5.3544 1 221125_WJC_METTL3_EV_vs_WT_F10.14575.14575.4 2.67E-13 27/132 R.K[136.11]VTFFEPGSGDENGTSNK[136.11]EDEFR[166.11].M "sp|O95793|STAU1_HUMAN,tr|Q5JW30|Q5JW30_HUMAN" 2 2615.1986 2.44 145171 14575 4 2615.188865 654.8069 Double-stranded RNA-binding protein Staufen homolog 1 OS=Homo sapiens OX=9606 GN=STAU1 PE=1 SV=2 4.36 2705.2 - 1.06E+06 - - - -3.7263 - 5.079 0.702 - 786 1 2 1 -0.0097 23 0 0 0 9.23E+07 3.79E+07 - - - 5.86 1 221125_WJC_METTL3_EV_vs_WT_F10.14588.14588.4 1.54E-11 20/126 K.DHTPSQELALTQSVGGDSSADR[166.11].L "sp|Q86U44|MTA70_HUMAN,tr|H0YFV6|H0YFV6_HUMAN" 2 2280.0494 0.01 145176 14588 4 2280.040477 571.0196 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 4.22 2706.9 - 3.58E+06 - - - -3.899 - 4.228 0.645 - 275.8 1 2 0 -0.0089 22 0 0 0 1.35E+06 9.66E+07 - - - 5.3094 1 221125_WJC_METTL3_EV_vs_WT_F10.14593.14593.4 9.36E-10 24/102 R.HPDSHQLFIGNLPHEVDK[136.11].S "sp|Q13283|G3BP1_HUMAN,tr|A0A7I2V5M7|A0A7I2V5M7_HUMAN,tr|A0A7I2V2X7|A0A7I2V2X7_HUMAN,tr|A0A7P0P2U7|A0A7P0P2U7_HUMAN,tr|A0A7I2YQN9|A0A7I2YQN9_HUMAN,tr|A0A7I2YQH0|A0A7I2YQH0_HUMAN" 6 2090.0425 1.2 145177 14593 4 2090.035326 523.5179 Ras GTPase-activating protein-binding protein 1 OS=Homo sapiens OX=9606 GN=G3BP1 PE=1 SV=1 5.73 2707.6 - 994147 - - - -3.4267 - 4.325 0.633 - 567.9 1 2 0 -0.0072 18 0 0 0 1.44E+08 1.20E+08 - - - 5.2353 1 221125_WJC_METTL3_EV_vs_WT_F10.14602.14602.4 0.000138 29/102 R.HPDSHQLFIGNLPHEVDK.S "sp|Q13283|G3BP1_HUMAN,tr|A0A7I2V5M7|A0A7I2V5M7_HUMAN,tr|A0A7I2V2X7|A0A7I2V2X7_HUMAN,tr|A0A7P0P2U7|A0A7P0P2U7_HUMAN,tr|A0A7I2YQN9|A0A7I2YQN9_HUMAN,tr|A0A7I2YQH0|A0A7I2YQH0_HUMAN" 6 2082.0283 1.14 145179 14602 4 2082.024813 521.5143 Ras GTPase-activating protein-binding protein 1 OS=Homo sapiens OX=9606 GN=G3BP1 PE=1 SV=1 5.73 2709 - 2.13E+06 - - - -1.669 - 4.553 0.561 - 886.7 1 2 0 -0.0035 18 0 0 0 1.45E+08 1.27E+08 - - - 4.6272 1 221125_WJC_METTL3_EV_vs_WT_F10.14610.14610.3 5.49E-14 24/112 R.VPSAAC[160.03]PPFPPHGAPVSASSSSSSPGGSR.G sp|Q9H7S9|ZN703_HUMAN 1 2734.2769 29.58 145182 14610 3 2734.275361 912.4329 Zinc finger protein 703 OS=Homo sapiens OX=9606 GN=ZNF703 PE=1 SV=1 8.23 2710.1 - 569303 - - - -0.5727 - 4.293 0.697 - 322.3 1 2 0 -0.0016 29 0 0 0 3.54E+07 1.20E+06 - - - 9.6624 0.9964 221125_WJC_METTL3_EV_vs_WT_F10.14613.14613.4 0.000107 12/120 R.EQQAQVEK[136.11]EDFSDMVAEHAAK[136.11].Q "sp|Q13435|SF3B2_HUMAN,tr|E9PPJ0|E9PPJ0_HUMAN,tr|H0YEX5|H0YEX5_HUMAN" 3 2405.114 0.93 145183 14613 4 2405.105899 602.2858 Splicing factor 3B subunit 2 OS=Homo sapiens OX=9606 GN=SF3B2 PE=1 SV=2 4.35 2710.5 - 863271 - - - -3.3699 - 2.257 0.373 - 61.8 1 2 1 -0.0081 21 0 0 0 1.66E+07 1.79E+07 - - - 2.7395 0.9997 221125_WJC_METTL3_EV_vs_WT_F10.14615.14615.3 1.76E-07 12/124 K.QLSQATAAATNHTTDNGVGPEEESVDPNQYYK.L "sp|Q15046|SYK_HUMAN,tr|H3BVA8|H3BVA8_HUMAN" 2 3434.5499 0.65 145185 14615 3 3434.533811 1145.8572 Lysine--tRNA ligase OS=Homo sapiens OX=9606 GN=KARS1 PE=1 SV=3 4.17 2710.7 - 772916 - - - -4.6702 - 3.207 0.52 - 47.5 1 2 0 -0.016 32 0 0 0 1.53E+07 2.35E+07 - - - 7.0141 1 221125_WJC_METTL3_EV_vs_WT_F10.14616.14616.3 3.04E-08 Dec-88 R.SMDSYLNQSYGMDNHSGGGGGSR.F sp|Q5BKZ1|ZN326_HUMAN 1 2375.9495 13.14 145186 14616 3 2375.95633 792.9905 DBIRD complex subunit ZNF326 OS=Homo sapiens OX=9606 GN=ZNF326 PE=1 SV=2 5.19 2710.9 - 364896 - - - 2.8658 - 2.339 0.688 - 94.5 1 2 0 0.0068 23 0 0 0 1.60E+07 1.22E+06 - - - 8.202 1 221125_WJC_METTL3_EV_vs_WT_F10.14620.14620.3 1.49E-06 17/124 K.QLSQATAAATNHTTDNGVGPEEESVDPNQYYK[136.11].L "sp|Q15046|SYK_HUMAN,tr|H3BVA8|H3BVA8_HUMAN" 2 3442.5641 0.65 145187 14620 3 3442.555439 1148.5286 Lysine--tRNA ligase OS=Homo sapiens OX=9606 GN=KARS1 PE=1 SV=3 4.17 2711.5 - 1.23E+06 - - - -2.5016 - 3.149 0.595 - 117.6 1 2 0 -0.0086 32 0 0 0 1.53E+07 2.35E+07 - - - 7.8103 0.9999 221125_WJC_METTL3_EV_vs_WT_F10.14624.14624.4 2.08E-09 20/126 R.KLTALDYHNPAGFNC[160.03]KDETEFR.N "sp|Q9Y224|RTRAF_HUMAN,tr|G3V4C6|G3V4C6_HUMAN,tr|G3V4E7|G3V4E7_HUMAN" 3 2625.2282 1.3 145189 14624 4 2625.233448 657.3143 "RNA transcription, translation and transport factor protein OS=Homo sapiens OX=9606 GN=RTRAF PE=1 SV=1" 5.48 2711.9 - 511076 - - - 2.0044 - 3.998 0.599 - 295.5 1 2 1 0.0053 22 0 0 0 2.27E+07 1.74E+07 - - - 4.8917 1 221125_WJC_METTL3_EV_vs_WT_F10.14629.14629.4 1.15E-12 24/132 K.YQGDGIVEDEEETMENNEEKKDR.R "sp|Q9NYF8|BCLF1_HUMAN,tr|H0YF63|H0YF63_HUMAN,tr|E9PK91|E9PK91_HUMAN,tr|H0YF14|H0YF14_HUMAN" 4 2756.1719 2.43 145191 14629 4 2756.169865 690.0503 Bcl-2-associated transcription factor 1 OS=Homo sapiens OX=9606 GN=BCLAF1 PE=1 SV=2 4 2712.5 - 9.70E+06 - - - -0.7431 - 5.144 0.649 - 596.5 1 2 1 -0.002 23 0 0 0 2.11E+09 8.70E+08 - - - 5.405 1 221125_WJC_METTL3_EV_vs_WT_F10.14630.14630.4 4.43E-08 19/126 R.K[136.11]LTALDYHNPAGFNC[160.03]K[136.11]DETEFR[166.11].N "sp|Q9Y224|RTRAF_HUMAN,tr|G3V4C6|G3V4C6_HUMAN,tr|G3V4E7|G3V4E7_HUMAN" 3 2651.2649 1.37 145192 14630 4 2651.261328 663.8235 "RNA transcription, translation and transport factor protein OS=Homo sapiens OX=9606 GN=RTRAF PE=1 SV=1" 5.48 2712.6 - 348340 - - - -1.3307 - 3.817 0.621 - 243.4 1 2 1 -0.0035 22 0 0 0 2.43E+07 1.77E+07 - - - 5.0685 1 221125_WJC_METTL3_EV_vs_WT_F10.14631.14631.3 1.52E-07 22/88 K.YQGDGIVEDEEETMENNEEKKDR.R "sp|Q9NYF8|BCLF1_HUMAN,tr|H0YF63|H0YF63_HUMAN,tr|E9PK91|E9PK91_HUMAN,tr|H0YF14|H0YF14_HUMAN" 4 2756.1719 2.42 145193 14631 3 2756.170685 919.7312 Bcl-2-associated transcription factor 1 OS=Homo sapiens OX=9606 GN=BCLAF1 PE=1 SV=2 4 2712.8 - 907561 - - - -0.4455 - 4.312 0.651 - 597 1 2 1 -0.0012 23 0 0 0 2.13E+08 8.80E+07 - - - 9.226 0.9993 221125_WJC_METTL3_EV_vs_WT_F10.14632.14632.2 4.10E-05 Oct-32 R.ISIGGGSC[160.03]AISGGYGSR.A "sp|P48668|K2C6C_HUMAN,sp|P04259|K2C6B_HUMAN,sp|P02538|K2C6A_HUMAN" 3 1597.7519 999 145194 14632 2 1597.757804 799.8832 "Keratin, type II cytoskeletal 6C OS=Homo sapiens OX=9606 GN=KRT6C PE=1 SV=3" 8.22 2712.9 - 228262 - - - 3.7234 - 2.445 0.587 - 212.1 1 2 0 0.0059 17 0 0 0 5.06E+06 0.00E+00 - - - 5.5728 1 221125_WJC_METTL3_EV_vs_WT_F10.14635.14635.4 5.87E-11 29/132 K.YQGDGIVEDEEETMENNEEK[136.11]K[136.11]DR[166.11].R "sp|Q9NYF8|BCLF1_HUMAN,tr|H0YF63|H0YF63_HUMAN,tr|E9PK91|E9PK91_HUMAN,tr|H0YF14|H0YF14_HUMAN" 4 2782.2086 2.43 145195 14635 4 2782.206689 696.5594 Bcl-2-associated transcription factor 1 OS=Homo sapiens OX=9606 GN=BCLAF1 PE=1 SV=2 4 2713.3 - 6.86E+06 - - - -0.6808 - 5.446 0.683 - 978.5 1 2 1 -0.0019 23 0 0 0 2.12E+09 8.70E+08 - - - 5.7194 0.9991 221125_WJC_METTL3_EV_vs_WT_F10.14641.14641.4 3.30E-06 22/120 K.SQHQEDPNNTSLLTNKPALLR.S "sp|Q6KC79|NIPBL_HUMAN,tr|A0A590UJS4|A0A590UJS4_HUMAN" 2 2375.2193 3.09 145199 14641 4 2376.221653 594.8121 Nipped-B-like protein OS=Homo sapiens OX=9606 GN=NIPBL PE=1 SV=2 6.47 2714.1 - 602605 - - - 421.9892 - 3.192 0.51 - 367.2 1 2 0 1.0023 21 0 0 0 2.89E+07 9.37E+06 - - - 3.7712 1 221125_WJC_METTL3_EV_vs_WT_F10.14649.14649.3 0.000366 25/88 K.YQGDGIVEDEEETMENNEEK[136.11]K[136.11]DR[166.11].R "sp|Q9NYF8|BCLF1_HUMAN,tr|H0YF63|H0YF63_HUMAN,tr|E9PK91|E9PK91_HUMAN,tr|H0YF14|H0YF14_HUMAN" 4 2782.2086 2.42 145203 14649 3 2782.204526 928.4101 Bcl-2-associated transcription factor 1 OS=Homo sapiens OX=9606 GN=BCLAF1 PE=1 SV=2 4 2715.1 - 1.10E+06 - - - -1.4582 - 4.87 0.705 - 694.9 1 2 1 -0.0041 23 0 0 0 2.13E+08 8.80E+07 - - - 10.1128 1 221125_WJC_METTL3_EV_vs_WT_F10.14651.14651.3 7.30E-08 17/136 K.GPGAHASGAAGTAPAPPGEPPAPGTC[160.03]DPAFYPSQR.S sp|A6NJT0|UNC4_HUMAN 1 3313.5211 5.59 145205 14651 3 3313.518061 1105.5143 Homeobox protein unc-4 homolog OS=Homo sapiens OX=9606 GN=UNCX PE=3 SV=1 5.32 2715.4 - 286365 - - - -0.9093 - 3.263 0.655 - 136.2 1 2 0 -0.003 35 0 0 0 9.56E+06 1.71E+06 - - - 8.5626 0.9994 221125_WJC_METTL3_EV_vs_WT_F10.14652.14652.4 2.28E-07 11/162 R.LSDVDANTAIK[136.11]HEEQSNEDIPIAEQSSK[136.11].D "sp|Q12888|TP53B_HUMAN,tr|A6NNK5|A6NNK5_HUMAN,tr|C9JXV0|C9JXV0_HUMAN" 3 3083.4866 0.96 145206 14652 4 3083.486103 771.8789 TP53-binding protein 1 OS=Homo sapiens OX=9606 GN=TP53BP1 PE=1 SV=2 4.19 2715.5 - 225240 - - - -0.1553 - 2.78 0.391 - 49.8 1 2 1 -0.0005 28 0 0 0 3.45E+06 3.60E+06 - - - 2.9466 1 221125_WJC_METTL3_EV_vs_WT_F10.14657.14657.4 4.09E-11 23/204 K.GPGAHASGAAGTAPAPPGEPPAPGTC[160.03]DPAFYPSQR.S sp|A6NJT0|UNC4_HUMAN 1 3313.5211 6.37 145209 14657 4 3313.522926 829.3875 Homeobox protein unc-4 homolog OS=Homo sapiens OX=9606 GN=UNCX PE=3 SV=1 5.32 2716.2 - 414349 - - - 0.5589 - 3.44 0.67 - 201 1 2 0 0.0019 35 0 0 0 1.15E+07 1.81E+06 - - - 5.4234 1 221125_WJC_METTL3_EV_vs_WT_F10.14661.14661.4 3.77E-11 22/120 K.SQHQEDPNNTSLLTNK[136.11]PALLR[166.11].S "sp|Q6KC79|NIPBL_HUMAN,tr|A0A590UJS4|A0A590UJS4_HUMAN" 2 2393.2418 3.08 145211 14661 4 2393.253496 599.3177 Nipped-B-like protein OS=Homo sapiens OX=9606 GN=NIPBL PE=1 SV=2 6.47 2716.7 - 553940 - - - 4.8846 - 3.602 0.636 - 313.6 1 2 0 0.0117 21 0 0 0 2.88E+07 9.37E+06 - - - 5.1822 0.9997 221125_WJC_METTL3_EV_vs_WT_F10.14663.14663.4 0.00178 14/126 R.QHEAPSNR[166.11]PLNELLTPQGPSPR[166.11].T sp|P10398|ARAF_HUMAN 1 2457.2628 0.39 145213 14663 4 2457.262341 615.323 Serine\threonine-protein kinase A-Raf OS=Homo sapiens OX=9606 GN=ARAF PE=1 SV=2 6.76 2717 - 476522 - - - -0.1701 - 2.158 0.354 - 104.9 1 2 0 -0.0004 22 0 0 0 9.00E+06 2.30E+07 - - - 2.5588 1 221125_WJC_METTL3_EV_vs_WT_F10.14675.14675.4 1.18E-07 Nov-90 K.K[136.11]HLEINPDHSIIETLR[166.11].Q sp|P07900|HS90A_HUMAN 1 1932.0548 0.5 145220 14675 4 1932.053807 484.021 Heat shock protein HSP 90-alpha OS=Homo sapiens OX=9606 GN=HSP90AA1 PE=1 SV=5 6.01 2718.5 - 202890 - - - -0.5036 - 2.419 0.549 - 115.2 1 2 0 -0.001 16 0 0 0 5.90E+06 1.19E+07 - - - 4.3154 0.9997 221125_WJC_METTL3_EV_vs_WT_F10.14676.14676.3 0.000832 13/56 R.ADTQTYQPYNK[136.11]DWIK[136.11].E sp|P84090|ERH_HUMAN 1 1885.9181 2.82 145221 14676 3 1885.918065 629.6467 Enhancer of rudimentary homolog OS=Homo sapiens OX=9606 GN=ERH PE=1 SV=1 6 2718.6 - 491489 - - - -0.0334 - 2.406 0.421 - 249.5 1 2 1 -0.0001 15 0 0 0 5.56E+07 1.97E+07 - - - 5.5247 0.9999 221125_WJC_METTL3_EV_vs_WT_F10.14677.14677.4 3.84E-05 14/90 R.ETNLDSLPLVDTHSK[136.11]R[166.11].T sp|P08670|VIME_HUMAN 1 1841.9602 1.85 145222 14677 4 1841.958578 461.4973 Vimentin OS=Homo sapiens OX=9606 GN=VIM PE=1 SV=4 5.38 2718.8 - 118134 - - - -0.8866 - 2.392 0.456 - 123.6 1 2 0 -0.0016 16 0 0 0 2.41E+07 1.30E+07 - - - 3.5018 0.9999 221125_WJC_METTL3_EV_vs_WT_F10.14686.14686.4 8.50E-05 15/156 R.RQPPARPPGPSTDTGALADGVVSQAVK.E sp|Q92917|GPKOW_HUMAN 1 2671.4042 1.66 145227 14686 4 2671.404234 668.8583 G-patch domain and KOW motifs-containing protein OS=Homo sapiens OX=9606 GN=GPKOW PE=1 SV=2 8.75 2720 - 324940 - - - 0.0213 - 3.001 0.454 - 98.7 1 2 0 0.0001 27 0 0 0 2.58E+07 1.55E+07 - - - 3.5215 1 221125_WJC_METTL3_EV_vs_WT_F10.14690.14690.4 2.68E-05 15/90 R.ETNLDSLPLVDTHSKR.T sp|P08670|VIME_HUMAN 1 1823.9377 1.85 145229 14690 4 1823.939161 456.9917 Vimentin OS=Homo sapiens OX=9606 GN=VIM PE=1 SV=4 5.38 2720.4 - 282057 - - - 0.7785 - 2.963 0.507 - 249.7 1 2 0 0.0014 16 0 0 0 2.41E+07 1.30E+07 - - - 4.0212 0.9999 221125_WJC_METTL3_EV_vs_WT_F10.14691.14691.4 3.59E-07 15/102 K.TANK[136.11]DHLVTAYNHLFETK[136.11].R sp|Q00688|FKBP3_HUMAN 1 2117.0877 0.12 145230 14691 4 2117.087045 530.2792 Peptidyl-prolyl cis-trans isomerase FKBP3 OS=Homo sapiens OX=9606 GN=FKBP3 PE=1 SV=1 6.62 2720.5 - 399897 - - - -0.2872 - 3.526 0.535 - 188.1 1 2 1 -0.0006 18 0 0 0 7.29E+06 5.87E+07 - - - 4.3141 0.9848 221125_WJC_METTL3_EV_vs_WT_F10.14697.14697.2 0.159 14-May R.AFLIEEQK.L sp|P49207|RL34_HUMAN 1 976.5229 76.88 145233 14697 2 976.523515 489.2687 60S ribosomal protein L34 OS=Homo sapiens OX=9606 GN=RPL34 PE=1 SV=3 4.53 2721.3 - 101609 - - - 0.5817 - 1.102 0.188 - 62.2 5 2 0 0.0006 8 0 0 0 3.77E+06 4.90E+04 - - - 0.4101 0.9886 221125_WJC_METTL3_EV_vs_WT_F10.14701.14701.4 0.00414 10/174 K.QNPSLPAPQTLAGGNPETAQPHAGTLPRPR.P "sp|Q68EM7|RHG17_HUMAN,tr|I3L3P1|I3L3P1_HUMAN,tr|I3L4Y5|I3L4Y5_HUMAN,tr|I3L460|I3L460_HUMAN" 4 3072.5853 2.98 145236 14701 4 3072.584869 769.1536 Rho GTPase-activating protein 17 OS=Homo sapiens OX=9606 GN=ARHGAP17 PE=1 SV=1 9.61 2721.8 - 333418 - - - -0.1497 - 1.969 0.435 - 33.9 1 1 0 -0.0005 30 0 0 0 7.38E+06 2.47E+06 - - - 3.2194 0.9999 221125_WJC_METTL3_EV_vs_WT_F10.14703.14703.3 4.62E-10 Oct-84 K.AK[136.11]ENDENC[160.03]GPTTTVFVGNISEK[136.11].A "sp|P49756|RBM25_HUMAN,tr|E9PQU5|E9PQU5_HUMAN,tr|E9PSE8|E9PSE8_HUMAN" 3 2425.1402 1.02 145238 14703 3 2425.134121 809.3873 RNA-binding protein 25 OS=Homo sapiens OX=9606 GN=RBM25 PE=1 SV=3 4.41 2722 - 152756 - - - -2.5145 - 2.236 0.694 - 80.3 1 2 1 -0.0061 22 0 0 0 2.03E+07 1.99E+07 - - - 8.1835 0.9999 221125_WJC_METTL3_EV_vs_WT_F10.14711.14711.4 0.00467 12/156 R.R[166.11]QPPAR[166.11]PPGPSTDTGALADGVVSQAVK[136.11].E sp|Q92917|GPKOW_HUMAN 1 2699.4349 1.65 145242 14711 4 2699.438213 675.866 G-patch domain and KOW motifs-containing protein OS=Homo sapiens OX=9606 GN=GPKOW PE=1 SV=2 8.75 2723 - 248846 - - - 1.221 - 2.374 0.469 - 55.8 1 2 0 0.0033 27 0 0 0 2.56E+07 1.55E+07 - - - 3.5778 0.9767 221125_WJC_METTL3_EV_vs_WT_F10.14718.14718.4 0.0318 12/102 K.TANKDHLVTAYNHLFETK.R sp|Q00688|FKBP3_HUMAN 1 2101.0593 0.12 145245 14718 4 2101.058019 526.2721 Peptidyl-prolyl cis-trans isomerase FKBP3 OS=Homo sapiens OX=9606 GN=FKBP3 PE=1 SV=1 6.62 2723.9 - 337527 - - - -0.5873 - 1.729 0.223 - 51.5 1 2 1 -0.0012 18 0 0 0 7.29E+06 5.87E+07 - - - 1.3542 0.9995 221125_WJC_METTL3_EV_vs_WT_F10.14723.14723.3 1.05E-06 Oct-84 K.AKENDENC[160.03]GPTTTVFVGNISEK.A "sp|P49756|RBM25_HUMAN,tr|E9PQU5|E9PQU5_HUMAN,tr|E9PSE8|E9PSE8_HUMAN" 3 2409.1118 1.02 145248 14723 3 2409.119921 804.0445 RNA-binding protein 25 OS=Homo sapiens OX=9606 GN=RBM25 PE=1 SV=3 4.41 2724.6 - 318598 - - - 3.3631 - 2.087 0.592 - 56.8 1 2 1 0.0081 22 0 0 0 2.03E+07 1.99E+07 - - - 6.8823 0.9999 221125_WJC_METTL3_EV_vs_WT_F10.14728.14728.4 2.26E-06 17/150 K.LTLQHVNSNQC[160.03]LDKATEEDSQVPSIR.D sp|Q10472|GALT1_HUMAN 1 2981.4513 1.48 145251 14728 4 2981.449206 746.3701 Polypeptide N-acetylgalactosaminyltransferase 1 OS=Homo sapiens OX=9606 GN=GALNT1 PE=1 SV=1 4.75 2725.3 - 331396 - - - -0.6899 - 2.76 0.612 - 77.2 1 2 1 -0.0021 26 0 0 0 8.99E+06 6.07E+06 - - - 4.8725 1 221125_WJC_METTL3_EV_vs_WT_F10.14737.14737.4 5.16E-05 Nov-90 K.KHLEINPDHSIIETLR.Q sp|P07900|HS90A_HUMAN 1 1914.0323 0.5 145256 14737 4 1914.033177 479.5154 Heat shock protein HSP 90-alpha OS=Homo sapiens OX=9606 GN=HSP90AA1 PE=1 SV=5 6.01 2726.5 - 246043 - - - 0.453 - 2.135 0.509 - 104.2 1 2 0 0.0009 16 0 0 0 5.90E+06 1.19E+07 - - - 3.9233 1 221125_WJC_METTL3_EV_vs_WT_F10.14742.14742.4 0.000133 14/138 R.K[136.11]QYDAYGSAGFDPGASGSQHSYWK[136.11].G sp|Q96EY1|DNJA3_HUMAN 1 2622.1746 1.08 145259 14742 4 2622.169701 656.5509 "DnaJ homolog subfamily A member 3, mitochondrial OS=Homo sapiens OX=9606 GN=DNAJA3 PE=1 SV=2" 6.74 2727.1 - 295232 - - - -1.8801 - 2.79 0.502 - 77.3 1 2 0 -0.0049 24 0 0 0 3.22E+06 2.98E+06 - - - 3.9234 0.9708 221125_WJC_METTL3_EV_vs_WT_F10.14744.14744.4 6.54E-05 10/198 R.SDSPVPTAPTSGGPK[136.11]PSTASAVPELATDPELEK[136.11]K[136.11].L "sp|Q86U44|MTA70_HUMAN,tr|B4E349|B4E349_HUMAN,tr|F5H6D8|F5H6D8_HUMAN,tr|B4DTN4|B4DTN4_HUMAN" 4 3384.7363 0.31 145260 14744 4 3384.709737 847.1913 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 4.51 2727.3 - 266733 - - - -7.8364 - 2.178 0.351 - 33.6 1 2 0 -0.0265 34 0 0 0 2.97E+07 9.49E+07 - - - 2.5059 0.9999 221125_WJC_METTL3_EV_vs_WT_F10.14748.14748.3 0.0456 15/60 R.ETNLDSLPLVDTHSKR.T sp|P08670|VIME_HUMAN 1 1823.9377 2.21 145261 14748 3 1823.937665 608.9865 Vimentin OS=Homo sapiens OX=9606 GN=VIM PE=1 SV=4 5.38 2727.9 - 294525 - - - -0.0417 - 2.754 0.414 - 285.6 1 2 0 -0.0001 16 0 0 0 1.22E+07 5.53E+06 - - - 5.755 1 221125_WJC_METTL3_EV_vs_WT_F10.14753.14753.2 0.00022 24-Dec R.FSGSGSGTDFTLK.L "sp|A2NJV5|KV229_HUMAN,sp|A0A087WW87|KV240_HUMAN,sp|P06310|KV230_HUMAN,sp|A0A075B6S2|KVD29_HUMAN,sp|P01614|KVD40_HUMAN,sp|P01615|KVD28_HUMAN,sp|A0A075B6S6|KVD30_HUMAN,sp|A0A075B6P5|KV228_HUMAN,sp|A0A0A0MRZ7|KVD26_HUMAN" 9 1302.6092 29.43 145264 14753 2 1302.610303 652.3119 Immunoglobulin kappa variable 2-29 OS=Homo sapiens OX=9606 GN=IGKV2-29 PE=3 SV=2 5.84 2728.6 - 1.93E+06 - - - 0.8498 - 2.56 0.613 - 278.2 1 2 0 0.0011 13 0 0 0 3.20E+08 1.09E+07 - - - 5.9808 0.9999 221125_WJC_METTL3_EV_vs_WT_F10.14760.14760.4 1.06E-07 15/132 K.ANVNAVDKLESSHQLISEYKEER.L "sp|Q9UPS8|ANR26_HUMAN,tr|A0A6Q8PHI6|A0A6Q8PHI6_HUMAN,tr|A0A6Q8PF30|A0A6Q8PF30_HUMAN,tr|A0A6Q8PHK2|A0A6Q8PHK2_HUMAN,tr|A0A6Q8PH02|A0A6Q8PH02_HUMAN,tr|A0A6Q8PHK8|A0A6Q8PHK8_HUMAN,tr|E7ESJ3|E7ESJ3_HUMAN" 7 2658.3249 3.2 145268 14760 4 2658.326777 665.5885 Ankyrin repeat domain-containing protein 26 OS=Homo sapiens OX=9606 GN=ANKRD26 PE=1 SV=4 4.96 2729.5 - 214065 - - - 0.6974 - 3.554 0.487 - 101.1 1 2 2 0.0019 23 0 0 0 4.14E+06 1.29E+06 - - - 3.8752 1 221125_WJC_METTL3_EV_vs_WT_F10.14763.14763.4 4.88E-09 20/114 K.R[166.11]GLLQDDAHPTLVTYADHSK[136.11].L "sp|Q86U44|MTA70_HUMAN,tr|F5H6D8|F5H6D8_HUMAN,tr|H0YFV6|H0YFV6_HUMAN,tr|B4DTN4|B4DTN4_HUMAN" 4 2254.1461 0.02 145271 14763 4 2254.148715 564.5438 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 5.99 2729.8 - 583193 - - - 1.1534 - 3.462 0.566 - 290.6 1 2 0 0.0026 20 0 0 0 4.40E+05 2.57E+07 - - - 4.5669 1 221125_WJC_METTL3_EV_vs_WT_F10.14764.14764.2 2.52E-06 13/20 R.NPEAALSPTFR[166.11].S "sp|Q86U44|MTA70_HUMAN,tr|B4E349|B4E349_HUMAN,tr|F5H6D8|F5H6D8_HUMAN,tr|B4DTN4|B4DTN4_HUMAN" 4 1211.6174 0.001 145272 14764 2 1211.620326 606.816 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 6 2730 - 254137 - - - 2.4092 - 2.815 0.539 - 808.8 1 2 0 0.0029 11 0 0 0 0.00E+00 2.78E+08 - - - 5.821 1 221125_WJC_METTL3_EV_vs_WT_F10.14765.14765.3 2.78E-06 Oct-80 K.R[166.11]PIGSWEC[160.03]SVC[160.03]C[160.03]VSNNAEDNK[136.11].C sp|P49790|NU153_HUMAN 1 2499.0696 0.12 145273 14765 3 2499.06579 834.0305 Nuclear pore complex protein Nup153 OS=Homo sapiens OX=9606 GN=NUP153 PE=1 SV=2 4.68 2730.1 - 191356 - - - -1.5238 - 2.509 0.589 - 77.6 1 2 0 -0.0038 21 0 0 0 2.73E+05 2.34E+06 - - - 7.3111 0.9744 221125_WJC_METTL3_EV_vs_WT_F10.14773.14773.3 1.39 Oct-48 K.DRLLASTLVHSVK.K "sp|Q9NYF8|BCLF1_HUMAN,tr|E9PKI6|E9PKI6_HUMAN,tr|A0A1W2PQ43|A0A1W2PQ43_HUMAN,tr|E9PK91|E9PK91_HUMAN,tr|E9PJA7|E9PJA7_HUMAN,tr|E9PK09|E9PK09_HUMAN,tr|E9PQN2|E9PQN2_HUMAN" 7 1437.8304 0.91 145278 14773 3 1437.831103 480.2841 Bcl-2-associated transcription factor 1 OS=Homo sapiens OX=9606 GN=BCLAF1 PE=1 SV=2 8.75 2731.1 - 97089.2 - - - 0.5147 - 1.794 0.182 - 160.5 1 2 1 0.0007 13 0 0 0 3.96E+06 4.38E+06 - - - 2.1535 0.9998 221125_WJC_METTL3_EV_vs_WT_F10.14780.14780.4 8.72E-07 15/138 K.AVHTVDFTADKYHVVSGADDYTVK.L "sp|Q8TED0|UTP15_HUMAN,tr|H0Y8P4|H0Y8P4_HUMAN" 2 2637.2711 1.86 145281 14780 4 2637.275668 660.3251 U3 small nucleolar RNA-associated protein 15 homolog OS=Homo sapiens OX=9606 GN=UTP15 PE=1 SV=3 5.2 2732 - 568553 - - - 1.7332 - 3.463 0.499 - 138.3 1 2 1 0.0046 24 0 0 0 1.37E+07 7.33E+06 - - - 3.9667 1 221125_WJC_METTL3_EV_vs_WT_F10.14781.14781.3 2.15E-06 Oct-32 R.VVHIMDFQR.G "sp|P43243|MATR3_HUMAN,tr|D6RE02|D6RE02_HUMAN,tr|B3KM87|B3KM87_HUMAN,tr|A8MXP9|A8MXP9_HUMAN,tr|D6RAY2|D6RAY2_HUMAN,tr|D6R991|D6R991_HUMAN,tr|A0A0R4J2E8|A0A0R4J2E8_HUMAN,tr|D6RAM9|D6RAM9_HUMAN,tr|D6RIA2|D6RIA2_HUMAN,tr|H0Y8T4|H0Y8T4_HUMAN,tr|D6REM6|D6REM6_HUMAN,tr|D6RBI2|D6RBI2_HUMAN" 12 1143.5859 1.21 145282 14781 3 1143.587244 382.2026 Matrin-3 OS=Homo sapiens OX=9606 GN=MATR3 PE=1 SV=2 6.71 2732.2 - 122558 - - - 1.1761 - 1.881 0.547 - 166.8 1 2 0 0.0013 9 0 0 0 4.84E+06 3.99E+06 - - - 6.5423 0.8751 221125_WJC_METTL3_EV_vs_WT_F10.14782.14782.4 0.0029 9/120 R.DSFDDRGPSLNPVLDYDHGSR.S "sp|P43243|MATR3_HUMAN,tr|A8MXP9|A8MXP9_HUMAN,tr|D6R991|D6R991_HUMAN,tr|A0A0R4J2E8|A0A0R4J2E8_HUMAN,tr|D6REM6|D6REM6_HUMAN" 5 2361.0622 1.62 145283 14782 4 2361.073717 591.2728 Matrin-3 OS=Homo sapiens OX=9606 GN=MATR3 PE=1 SV=2 4.28 2732.3 - 195045 - - - 4.8923 - 1.895 0.252 - 52.6 1 2 1 0.0116 21 0 0 0 7.29E+06 4.51E+06 - - - 1.6276 0.9999 221125_WJC_METTL3_EV_vs_WT_F10.14788.14788.3 4.05E-05 Aug-32 R.VVHIMDFQR[166.11].G "sp|P43243|MATR3_HUMAN,tr|D6RE02|D6RE02_HUMAN,tr|B3KM87|B3KM87_HUMAN,tr|A8MXP9|A8MXP9_HUMAN,tr|D6RAY2|D6RAY2_HUMAN,tr|D6R991|D6R991_HUMAN,tr|A0A0R4J2E8|A0A0R4J2E8_HUMAN,tr|D6RAM9|D6RAM9_HUMAN,tr|D6RIA2|D6RIA2_HUMAN,tr|H0Y8T4|H0Y8T4_HUMAN,tr|D6REM6|D6REM6_HUMAN,tr|D6RBI2|D6RBI2_HUMAN" 12 1153.5942 1.19 145287 14788 3 1153.594996 385.5387 Matrin-3 OS=Homo sapiens OX=9606 GN=MATR3 PE=1 SV=2 6.71 2733.1 - 269760 - - - 0.7169 - 1.641 0.484 - 88.3 1 2 0 0.0008 9 0 0 0 4.75E+06 3.99E+06 - - - 5.4286 0.9927 221125_WJC_METTL3_EV_vs_WT_F10.14795.14795.3 2.23E-05 18/84 A.FASSLVSGLNSSASEPAK[136.11]EPAK[136.11].K "sp|Q86U44|MTA70_HUMAN,tr|F5H6D8|F5H6D8_HUMAN,tr|H0YFV6|H0YFV6_HUMAN,tr|B4DTN4|B4DTN4_HUMAN" 4 2192.1296 0.001 145292 14795 3 2192.12986 731.7171 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 6.14 2734 - 451199 - - - 0.1286 - 3.557 0.533 - 336.8 1 1 1 0.0003 22 0 0 0 0.00E+00 1.70E+07 - - - 7.4907 0.9999 221125_WJC_METTL3_EV_vs_WT_F10.14802.14802.3 1.45E-06 13/80 K.HGDEIITSTTSNYETQTFSSK[136.11].T sp|Q6P2Q9|PRP8_HUMAN 1 2353.0801 1.64 145297 14802 3 2353.087656 785.3673 Pre-mRNA-processing-splicing factor 8 OS=Homo sapiens OX=9606 GN=PRPF8 PE=1 SV=2 4.65 2735 - 287126 - - - 3.2047 - 2.518 0.566 - 201 1 2 0 0.0075 21 0 0 0 4.64E+06 2.83E+06 - - - 7.0622 1 221125_WJC_METTL3_EV_vs_WT_F10.14810.14810.3 1.41E-13 15/80 K.HGDEIITSTTSNYETQTFSSK.T sp|Q6P2Q9|PRP8_HUMAN 1 2345.0659 1.64 145302 14810 3 2345.071318 782.6959 Pre-mRNA-processing-splicing factor 8 OS=Homo sapiens OX=9606 GN=PRPF8 PE=1 SV=2 4.65 2736.1 - 302388 - - - 2.304 - 3.186 0.677 - 251 1 2 0 0.0054 21 0 0 0 4.64E+06 2.83E+06 - - - 8.8645 0.9998 221125_WJC_METTL3_EV_vs_WT_F10.14812.14812.4 0.000288 11/102 K.KKIEVIKPGDLGVDLTSK.L "sp|P38117|ETFB_HUMAN,tr|M0QY67|M0QY67_HUMAN" 2 1939.1354 2.16 145304 14812 4 1939.136073 485.7911 Electron transfer flavoprotein subunit beta OS=Homo sapiens OX=9606 GN=ETFB PE=1 SV=3 8.43 2736.3 - 129062 - - - 0.3584 - 2.041 0.479 - 104.9 1 2 1 0.0007 18 0 0 0 7.48E+06 3.47E+06 - - - 3.6394 0.9955 221125_WJC_METTL3_EV_vs_WT_F10.14824.14824.3 7.33E-12 19/92 A.AFASSLVSGLNSSASEPAK[136.11]EPAK[136.11]K[136.11].S "sp|Q86U44|MTA70_HUMAN,tr|F5H6D8|F5H6D8_HUMAN,tr|H0YFV6|H0YFV6_HUMAN,tr|B4DTN4|B4DTN4_HUMAN" 4 2399.2759 0.001 145312 14824 3 2399.275757 800.7659 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 8.54 2737.9 - 415540 - - - -0.0408 - 3.472 0.63 - 272.8 1 1 1 -0.0001 24 0 0 0 0.00E+00 1.81E+08 - - - 8.4549 1 221125_WJC_METTL3_EV_vs_WT_F10.14846.14846.3 3.43E-14 27/112 R.VPSAAC[160.03]PPFPPHGAPVSASSSSSSPGGSR.G sp|Q9H7S9|ZN703_HUMAN 1 2734.2769 2.6 145324 14846 3 2734.279876 912.4329 Zinc finger protein 703 OS=Homo sapiens OX=9606 GN=ZNF703 PE=1 SV=1 8.23 2740.9 - 404623 - - - 1.0785 - 4.958 0.734 - 412.1 1 2 0 0.0029 29 0 0 0 2.76E+07 1.06E+07 - - - 10.4059 0.9999 221125_WJC_METTL3_EV_vs_WT_F10.14848.14848.4 0.000208 12/108 R.GLLQDDAHPTLVTYADHSK[136.11].L "sp|Q86U44|MTA70_HUMAN,tr|F5H6D8|F5H6D8_HUMAN,tr|H0YFV6|H0YFV6_HUMAN,tr|B4DTN4|B4DTN4_HUMAN" 4 2088.0367 0.06 145325 14848 4 2088.037982 523.0165 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 5.13 2741.1 - 580463 - - - 0.5982 - 2.365 0.46 - 134.3 1 2 0 0.0012 19 0 0 0 7.74E+05 1.32E+07 - - - 3.5207 1 221125_WJC_METTL3_EV_vs_WT_F10.14858.14858.3 2.50E-05 Nov-96 K.TPVVQNAASIVQPSPAHVGQQGLSK.L "sp|Q8WXI9|P66B_HUMAN,tr|A0A0U1RRM1|A0A0U1RRM1_HUMAN" 2 2512.3398 2.11 145331 14858 3 2512.339313 838.4539 Transcriptional repressor p66-beta OS=Homo sapiens OX=9606 GN=GATAD2B PE=1 SV=1 8.44 2742.4 - 235582 - - - -0.1879 - 2.838 0.484 - 94.9 1 2 0 -0.0005 25 0 0 0 5.89E+06 2.79E+06 - - - 6.3358 0.9996 221125_WJC_METTL3_EV_vs_WT_F10.14868.14868.4 1.33E-05 12/102 R.VKEESSSISSLKDEFTQR.L "sp|P82094|TMF1_HUMAN,tr|F8WF45|F8WF45_HUMAN,tr|A0A2R8Y7M0|A0A2R8Y7M0_HUMAN" 3 2069.0277 1.58 145336 14868 4 2069.032637 518.2642 TATA element modulatory factor OS=Homo sapiens OX=9606 GN=TMF1 PE=1 SV=2 4.87 2743.8 - 338990 - - - 2.3968 - 2.175 0.488 - 86.7 1 2 2 0.005 18 0 0 0 2.22E+08 1.41E+08 - - - 3.7384 0.999 221125_WJC_METTL3_EV_vs_WT_F10.14870.14870.2 0.000165 20-Sep R.TNAENEFVTIK.K sp|P04264|K2C1_HUMAN 1 1264.6299 6.81 145338 14870 2 1264.634191 633.3222 "Keratin, type II cytoskeletal 1 OS=Homo sapiens OX=9606 GN=KRT1 PE=1 SV=6" 4.53 2744 - 219513 - - - 3.3678 - 1.894 0.487 - 316.7 1 2 0 0.0043 11 0 0 0 1.14E+07 1.68E+06 - - - 4.3645 1 221125_WJC_METTL3_EV_vs_WT_F10.14873.14873.4 1.44E-05 13/132 R.HTHLDDPIAEVEPTDSEPYSC[160.03]SK[136.11].S "sp|Q8TEU7|RPGF6_HUMAN,tr|E9PCH4|E9PCH4_HUMAN,tr|A0A5F9ZHG7|A0A5F9ZHG7_HUMAN" 3 2634.1635 0.36 145339 14873 4 2634.162717 659.5482 Rap guanine nucleotide exchange factor 6 OS=Homo sapiens OX=9606 GN=RAPGEF6 PE=1 SV=2 4.29 2744.4 - 133162 - - - -0.3075 - 2.72 0.496 - 84.3 1 2 0 -0.0008 23 0 0 0 1.87E+06 5.16E+06 - - - 3.8672 0.9999 221125_WJC_METTL3_EV_vs_WT_F10.14875.14875.4 9.73E-06 20/102 R.VK[136.11]EESSSISSLK[136.11]DEFTQR[166.11].L "sp|P82094|TMF1_HUMAN,tr|F8WF45|F8WF45_HUMAN,tr|A0A2R8Y7M0|A0A2R8Y7M0_HUMAN" 3 2095.0643 1.58 145340 14875 4 2095.066223 524.7734 TATA element modulatory factor OS=Homo sapiens OX=9606 GN=TMF1 PE=1 SV=2 4.87 2744.6 - 517787 - - - 0.895 - 3.655 0.514 - 344.3 1 2 2 0.0019 18 0 0 0 2.22E+08 1.41E+08 - - - 4.1433 1 221125_WJC_METTL3_EV_vs_WT_F10.14877.14877.3 2.20E-12 22/84 K.DHTPSQELALTQSVGGDSSADR[166.11].L "sp|Q86U44|MTA70_HUMAN,tr|H0YFV6|H0YFV6_HUMAN" 2 2280.0494 0 145342 14877 3 2280.04396 761.0237 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 4.22 2744.9 - 534862 - - - -2.3714 - 4.071 0.672 - 498.3 1 2 0 -0.0054 22 0 0 0 6.03E+04 1.43E+07 - - - 9.359 0.9854 221125_WJC_METTL3_EV_vs_WT_F10.14878.14878.4 0.000989 9/144 R.GTDIYLPYTPPSSESC[160.03]HDGYQHQEK[136.11].M "sp|Q2KHR3|QSER1_HUMAN,tr|A0A3B3IRW6|A0A3B3IRW6_HUMAN,tr|H0YCQ7|H0YCQ7_HUMAN" 3 2916.2752 1.84 145343 14878 4 2916.266366 730.0761 Glutamine and serine-rich protein 1 OS=Homo sapiens OX=9606 GN=QSER1 PE=1 SV=3 4.72 2745 - 184789 - - - -3.0302 - 1.851 0.232 - 28.5 1 2 0 -0.0088 25 0 0 0 1.05E+07 5.71E+06 - - - 1.4388 0.9985 221125_WJC_METTL3_EV_vs_WT_F10.14881.14881.4 0.0988 8/144 R.SEAEEAITSFNGHKPPGSSEPITVK.F sp|Q15717|ELAV1_HUMAN 1 2611.2766 1.26 145344 14881 4 2611.279305 653.8264 ELAV-like protein 1 OS=Homo sapiens OX=9606 GN=ELAVL1 PE=1 SV=2 4.9 2745.4 - 212921 - - - 1.0451 - 1.795 0.285 - 27.2 1 2 0 0.0027 25 0 0 0 2.71E+06 2.15E+06 - - - 1.892 0.99 221125_WJC_METTL3_EV_vs_WT_F10.14890.14890.3 0.333 Jul-36 R.K[136.11]QDSGHLDLR[166.11].N "sp|Q86U44|MTA70_HUMAN,tr|B4E349|B4E349_HUMAN,tr|F5H6D8|F5H6D8_HUMAN,tr|B4DTN4|B4DTN4_HUMAN" 4 1185.6221 0.01 145350 14890 3 1185.622314 396.2146 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 6.75 2746.6 - 138063 - - - 0.1763 - 1.196 0.246 - 83.7 1 2 0 0.0002 10 0 0 0 2.39E+04 4.19E+06 - - - 1.8053 0.9523 221125_WJC_METTL3_EV_vs_WT_F10.14894.14894.3 0.00256 8/108 E.SRMSGEC[160.03]APNVSVSVSTSHTTISGGGSR.G sp|P04264|K2C1_HUMAN 1 2807.2927 999 145351 14894 3 2807.290787 936.7715 "Keratin, type II cytoskeletal 1 OS=Homo sapiens OX=9606 GN=KRT1 PE=1 SV=6" 7.99 2747.1 - 291366 - - - -0.6651 - 1.978 0.453 - 20.8 1 1 1 -0.0019 28 0 0 0 1.61E+07 0.00E+00 - - - 5.1592 1 221125_WJC_METTL3_EV_vs_WT_F10.14902.14902.4 1.44E-12 28/126 R.RIC[160.03]NAVSPDKDVDGFHVINVGR.M "sp|P13995|MTDC_HUMAN,tr|A0A7I2V482|A0A7I2V482_HUMAN,tr|A0A7I2V2U6|A0A7I2V2U6_HUMAN,tr|A0A7I2YQD4|A0A7I2YQD4_HUMAN,tr|B8ZZU9|B8ZZU9_HUMAN" 5 2467.239 1.1 145357 14902 4 2467.243915 617.817 "Bifunctional methylenetetrahydrofolate dehydrogenase\cyclohydrolase, mitochondrial OS=Homo sapiens OX=9606 GN=MTHFD2 PE=1 SV=2" 6.74 2748.2 - 429088 - - - 1.9816 - 5.04 0.646 - 717.1 1 2 1 0.0049 22 0 0 0 9.12E+06 8.26E+06 - - - 5.3767 1 221125_WJC_METTL3_EV_vs_WT_F10.14907.14907.4 1.75E-16 26/126 R.R[166.11]IC[160.03]NAVSPDK[136.11]DVDGFHVINVGR[166.11].M "sp|P13995|MTDC_HUMAN,tr|A0A7I2V482|A0A7I2V482_HUMAN,tr|A0A7I2V2U6|A0A7I2V2U6_HUMAN,tr|A0A7I2YQD4|A0A7I2YQD4_HUMAN,tr|B8ZZU9|B8ZZU9_HUMAN" 5 2495.2698 1.1 145360 14907 4 2495.271383 624.8247 "Bifunctional methylenetetrahydrofolate dehydrogenase\cyclohydrolase, mitochondrial OS=Homo sapiens OX=9606 GN=MTHFD2 PE=1 SV=2" 6.74 2748.8 - 425979 - - - 0.648 - 4.794 0.709 - 478.6 1 2 1 0.0016 22 0 0 0 9.12E+06 8.26E+06 - - - 5.9095 0.9987 221125_WJC_METTL3_EV_vs_WT_F10.14908.14908.4 0.000885 10/144 K.VGAVDADKHHSLGGQYGVQGFPTIK.L sp|Q15084|PDIA6_HUMAN 1 2580.3085 1.13 145361 14908 4 2580.307119 646.0844 Protein disulfide-isomerase A6 OS=Homo sapiens OX=9606 GN=PDIA6 PE=1 SV=1 6.89 2749 - 239384 - - - -0.5294 - 1.697 0.365 - 62.9 1 2 1 -0.0014 25 0 0 0 3.57E+07 3.15E+07 - - - 2.5708 0.9991 221125_WJC_METTL3_EV_vs_WT_F10.14911.14911.3 1.76E-07 13/112 R.VPSAAC[160.03]PPFPPHGAPVSASSSSSSPGGSR[166.11].G sp|Q9H7S9|ZN703_HUMAN 1 2744.2852 2.65 145362 14911 3 2744.303935 915.769 Zinc finger protein 703 OS=Homo sapiens OX=9606 GN=ZNF703 PE=1 SV=1 8.23 2749.4 - 200219 - - - 6.828 - 2.66 0.587 - 71.1 1 2 0 0.0187 29 0 0 0 9.78E+06 3.69E+06 - - - 7.3301 0.9994 221125_WJC_METTL3_EV_vs_WT_F10.14912.14912.4 0.00477 Sep-96 K.K[136.11]YFLHDDR[166.11]DDGVDYWAK[136.11].R "sp|Q9NYF8|BCLF1_HUMAN,tr|H0YF14|H0YF14_HUMAN" 2 2168.0173 2.28 145363 14912 4 2168.01491 543.0116 Bcl-2-associated transcription factor 1 OS=Homo sapiens OX=9606 GN=BCLAF1 PE=1 SV=2 4.66 2749.5 - 265210 - - - -1.1204 - 1.933 0.406 - 44.4 1 2 1 -0.0024 17 0 0 0 8.78E+07 3.86E+07 - - - 2.988 0.9997 221125_WJC_METTL3_EV_vs_WT_F10.14921.14921.4 0.000433 13/90 R.STDTSLKDGLFHEFKK.F "sp|Q96T58|MINT_HUMAN,tr|H0Y5U7|H0Y5U7_HUMAN,tr|A0A669KB49|A0A669KB49_HUMAN,tr|F6WRY4|F6WRY4_HUMAN" 4 1851.9367 1.32 145370 14921 4 1851.93567 463.9914 Msx2-interacting protein OS=Homo sapiens OX=9606 GN=SPEN PE=1 SV=1 6.47 2750.7 - 189410 - - - -0.5448 - 2.357 0.431 - 80.2 1 2 1 -0.001 16 0 0 0 5.18E+06 3.92E+06 - - - 3.2792 0.9998 221125_WJC_METTL3_EV_vs_WT_F10.14925.14925.4 9.29E-06 15/144 K.VGAVDADK[136.11]HHSLGGQYGVQGFPTIK[136.11].L sp|Q15084|PDIA6_HUMAN 1 2596.3369 1.13 145372 14925 4 2596.339901 650.0915 Protein disulfide-isomerase A6 OS=Homo sapiens OX=9606 GN=PDIA6 PE=1 SV=1 6.89 2751.3 - 368445 - - - 1.1616 - 2.281 0.476 - 117.9 1 2 1 0.003 25 0 0 0 3.56E+07 3.15E+07 - - - 3.6306 0.9987 221125_WJC_METTL3_EV_vs_WT_F10.14927.14927.3 5.31E-12 16/72 K.PSTASAVPELATDPELEK[136.11]K[136.11].L "sp|Q86U44|MTA70_HUMAN,tr|B4E349|B4E349_HUMAN,tr|F5H6D8|F5H6D8_HUMAN,tr|H0YFV6|H0YFV6_HUMAN,tr|B4DTN4|B4DTN4_HUMAN" 5 1998.0492 0 145374 14927 3 1998.048709 667.0237 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 4.41 2751.5 - 352406 - - - -0.2467 - 3.233 0.577 - 265.5 1 1 0 -0.0005 19 0 0 0 1.99E+05 1.01E+08 - - - 7.8557 1 221125_WJC_METTL3_EV_vs_WT_F10.14930.14930.4 2.34E-06 17/138 K.QTAISQPASGNTFSHHSMVSMLGK[136.11].G "sp|Q14157|UBP2L_HUMAN,tr|F8W726|F8W726_HUMAN" 2 2523.209 0.51 145375 14930 4 2523.210494 631.8095 Ubiquitin-associated protein 2-like OS=Homo sapiens OX=9606 GN=UBAP2L PE=1 SV=2 8.76 2751.9 - 462259 - - - 0.6012 - 3.78 0.536 - 246.3 1 2 0 0.0015 24 0 0 0 4.17E+06 8.20E+06 - - - 4.3177 1 221125_WJC_METTL3_EV_vs_WT_F10.14932.14932.3 9.98E-11 26/68 R.VKEESSSISSLKDEFTQR.L "sp|P82094|TMF1_HUMAN,tr|F8WF45|F8WF45_HUMAN,tr|A0A2R8Y7M0|A0A2R8Y7M0_HUMAN" 3 2069.0277 1.49 145376 14932 3 2069.030936 690.6832 TATA element modulatory factor OS=Homo sapiens OX=9606 GN=TMF1 PE=1 SV=2 4.87 2752.1 - 5.07E+06 - - - 1.5747 - 4.919 0.628 - 1026.3 1 2 2 0.0033 18 0 0 0 1.44E+08 9.71E+07 - - - 9.5077 1 221125_WJC_METTL3_EV_vs_WT_F10.14938.14938.4 1.27E-07 18/144 R.SEAEEAITSFNGHK[136.11]PPGSSEPITVK[136.11].F sp|Q15717|ELAV1_HUMAN 1 2627.305 1.56 145380 14938 4 2627.3066 657.8335 ELAV-like protein 1 OS=Homo sapiens OX=9606 GN=ELAVL1 PE=1 SV=2 4.9 2752.9 - 575012 - - - 0.6181 - 3.158 0.57 - 151.4 1 2 0 0.0016 25 0 0 0 1.01E+08 6.47E+07 - - - 4.5526 0.9974 221125_WJC_METTL3_EV_vs_WT_F10.14939.14939.3 0.00205 Aug-64 K.K[136.11]YFLHDDR[166.11]DDGVDYWAK[136.11].R "sp|Q9NYF8|BCLF1_HUMAN,tr|H0YF14|H0YF14_HUMAN" 2 2168.0173 3.25 145381 14939 3 2168.020414 723.6797 Bcl-2-associated transcription factor 1 OS=Homo sapiens OX=9606 GN=BCLAF1 PE=1 SV=2 4.66 2753.1 - 266625 - - - 1.4183 - 1.88 0.345 - 70.6 1 2 1 0.0031 17 0 0 0 1.77E+07 5.46E+06 - - - 3.9803 0.9999 221125_WJC_METTL3_EV_vs_WT_F10.14963.14963.3 0.0537 13/52 K.AQIHDLVLVGGSTR[166.11].L "sp|P0DMV8|HS71A_HUMAN,sp|P0DMV9|HS71B_HUMAN,tr|V9GZ37|V9GZ37_HUMAN,tr|A0A0G2JIW1|A0A0G2JIW1_HUMAN" 4 1474.8131 0.31 145390 14963 3 1474.812157 492.6117 Heat shock 70 kDa protein 1A OS=Homo sapiens OX=9606 GN=HSPA1A PE=1 SV=1 6.79 2756.5 - 234429 - - - -0.6706 - 2.354 0.431 - 198.9 1 2 0 -0.001 14 0 0 0 7.43E+06 2.38E+07 - - - 5.6201 0.9994 221125_WJC_METTL3_EV_vs_WT_F10.14966.14966.4 1.11E-06 15/138 K.NIDDGTSDRPYSHALVAGIDRYPR.K "sp|P61353|RL27_HUMAN,tr|K7ELC7|K7ELC7_HUMAN" 2 2687.3052 1.22 145393 14966 4 2687.313293 672.8336 60S ribosomal protein L27 OS=Homo sapiens OX=9606 GN=RPL27 PE=1 SV=2 5.36 2756.9 - 230895 - - - 3.0149 - 2.228 0.485 - 75 1 2 1 0.0081 24 0 0 0 6.53E+07 5.36E+07 - - - 3.7023 0.8776 221125_WJC_METTL3_EV_vs_WT_F10.14970.14970.4 0.0679 9/120 K.K[136.11]LDASILEDR[166.11]DK[136.11]PYAC[160.03]DIC[160.03]GK[136.11].R sp|Q92785|REQU_HUMAN 1 2500.2392 1.07 145395 14970 4 2500.238407 626.0671 Zinc finger protein ubi-d4 OS=Homo sapiens OX=9606 GN=DPF2 PE=1 SV=2 4.78 2757.4 - 197446 - - - -0.3036 - 1.837 0.152 - 57.2 1 2 1 -0.0008 21 0 0 0 4.90E+06 4.57E+06 - - - 0.7499 0.9999 221125_WJC_METTL3_EV_vs_WT_F10.14975.14975.4 8.88E-05 11/108 R.VIHLSNLPHSGYSDSAVLK.L "sp|P43243|MATR3_HUMAN,tr|B3KM87|B3KM87_HUMAN,tr|A8MXP9|A8MXP9_HUMAN,tr|D6RBK5|D6RBK5_HUMAN,tr|A0A0R4J2E8|A0A0R4J2E8_HUMAN,tr|H0Y8T4|H0Y8T4_HUMAN,tr|D6REM6|D6REM6_HUMAN" 7 2036.0691 1.36 145398 14975 4 2036.070765 510.0245 Matrin-3 OS=Homo sapiens OX=9606 GN=MATR3 PE=1 SV=2 6.89 2758.1 - 270745 - - - 0.8227 - 2.526 0.452 - 105.5 1 2 0 0.0017 19 0 0 0 8.65E+07 6.35E+07 - - - 3.4732 1 221125_WJC_METTL3_EV_vs_WT_F10.14981.14981.4 1.73E-13 31/174 K.IYQNIQDGSLDLNAAESGVQHK[136.11]PSAPQGGR[166.11].L sp|P61106|RAB14_HUMAN 1 3167.5715 1.12 145401 14981 4 3167.573151 792.9001 Ras-related protein Rab-14 OS=Homo sapiens OX=9606 GN=RAB14 PE=1 SV=4 5.38 2758.8 - 1.16E+06 - - - 0.5297 - 5.152 0.68 - 418.8 1 2 0 0.0017 30 0 0 0 7.83E+07 7.01E+07 - - - 5.6459 1 221125_WJC_METTL3_EV_vs_WT_F10.14982.14982.4 7.34E-10 18/108 R.VIHLSNLPHSGYSDSAVLK[136.11].L "sp|P43243|MATR3_HUMAN,tr|B3KM87|B3KM87_HUMAN,tr|A8MXP9|A8MXP9_HUMAN,tr|D6RBK5|D6RBK5_HUMAN,tr|A0A0R4J2E8|A0A0R4J2E8_HUMAN,tr|H0Y8T4|H0Y8T4_HUMAN,tr|D6REM6|D6REM6_HUMAN" 7 2044.0833 1.36 145402 14982 4 2044.080875 512.0281 Matrin-3 OS=Homo sapiens OX=9606 GN=MATR3 PE=1 SV=2 6.89 2759 - 405110 - - - -1.1815 - 3.566 0.609 - 286.5 1 2 0 -0.0024 19 0 0 0 8.64E+07 6.35E+07 - - - 4.9562 0.9671 221125_WJC_METTL3_EV_vs_WT_F10.14984.14984.4 0.0397 14/180 S.PVPTAPTSGGPK[136.11]PSTASAVPELATDPELEK[136.11]K[136.11].L "sp|Q86U44|MTA70_HUMAN,tr|B4E349|B4E349_HUMAN,tr|F5H6D8|F5H6D8_HUMAN,tr|B4DTN4|B4DTN4_HUMAN" 4 3095.6453 0.001 145404 14984 4 3095.651985 774.9186 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 4.87 2759.2 - 369811 - - - 2.1721 - 2.568 0.392 - 73.1 1 1 0 0.0067 31 0 0 0 0.00E+00 2.01E+07 - - - 2.9227 0.9999 221125_WJC_METTL3_EV_vs_WT_F10.14985.14985.4 0.000108 Nov-96 K.GYPHLC[160.03]SIC[160.03]DLPVHSNK.E "sp|P43243|MATR3_HUMAN,tr|A8MXP9|A8MXP9_HUMAN,tr|D6R991|D6R991_HUMAN,tr|A0A0R4J2E8|A0A0R4J2E8_HUMAN,tr|H0Y8T4|H0Y8T4_HUMAN,tr|D6REM6|D6REM6_HUMAN" 6 1995.9295 1.35 145405 14985 4 1995.932337 499.9897 Matrin-3 OS=Homo sapiens OX=9606 GN=MATR3 PE=1 SV=2 6.9 2759.4 - 262219 - - - 1.4204 - 1.991 0.442 - 65.6 1 2 0 0.0028 17 0 0 0 3.17E+07 2.34E+07 - - - 3.3115 1 221125_WJC_METTL3_EV_vs_WT_F10.14990.14990.4 4.52E-17 34/174 K.IYQNIQDGSLDLNAAESGVQHKPSAPQGGR.L sp|P61106|RAB14_HUMAN 1 3149.549 1.12 145408 14990 4 3149.5525 788.3945 Ras-related protein Rab-14 OS=Homo sapiens OX=9606 GN=RAB14 PE=1 SV=4 5.38 2760 - 2.75E+06 - - - 1.1103 - 5.415 0.694 - 529.6 1 2 0 0.0035 30 0 0 0 7.83E+07 7.01E+07 - - - 5.7825 0.9997 221125_WJC_METTL3_EV_vs_WT_F10.14991.14991.3 0.000249 Nov-60 K.ILDSVGIEADDDR[166.11]LNK[136.11].V sp|P05387|RLA2_HUMAN 1 1789.9177 1.28 145409 14991 3 1789.919541 597.6465 60S acidic ribosomal protein P2 OS=Homo sapiens OX=9606 GN=RPLP2 PE=1 SV=1 4.04 2760.2 - 279858 - - - 1.0408 - 2.315 0.45 - 113.9 1 2 1 0.0019 16 0 0 0 6.99E+06 5.48E+06 - - - 5.7104 0.9995 221125_WJC_METTL3_EV_vs_WT_F10.14992.14992.4 8.24E-05 19/138 K.NIDDGTSDR[166.11]PYSHALVAGIDR[166.11]YPR[166.11].K "sp|P61353|RL27_HUMAN,tr|K7ELC7|K7ELC7_HUMAN" 2 2717.33 1.22 145410 14992 4 2717.3367 680.3398 60S ribosomal protein L27 OS=Homo sapiens OX=9606 GN=RPL27 PE=1 SV=2 5.36 2760.3 - 1.77E+06 - - - 2.4653 - 2.564 0.458 - 129.6 1 2 1 0.0067 24 0 0 0 6.53E+07 5.36E+07 - - - 3.5128 0.9999 221125_WJC_METTL3_EV_vs_WT_F10.14996.14996.3 0.00491 Sep-40 R.AVFPSIVGRPR.Q "sp|Q6S8J3|POTEE_HUMAN,sp|P63261|ACTG_HUMAN,sp|P68133|ACTS_HUMAN,sp|P62736|ACTA_HUMAN,sp|Q9BYX7|ACTBM_HUMAN,sp|P68032|ACTC_HUMAN,sp|P60709|ACTB_HUMAN,sp|P63267|ACTH_HUMAN,sp|A5A3E0|POTEF_HUMAN,sp|P0CG38|POTEI_HUMAN,tr|A0A804GS07|A0A804GS07_HUMAN,tr|I3L3I0|I3L3I0_HUMAN,tr|G5E9R0|G5E9R0_HUMAN,tr|E7EVS6|E7EVS6_HUMAN,tr|B8ZZJ2|B8ZZJ2_HUMAN,tr|J3KT65|J3KT65_HUMAN,tr|I3L3R2|I3L3R2_HUMAN,tr|K7EM38|K7EM38_HUMAN,tr|F6QUT6|F6QUT6_HUMAN,tr|C9JTX5|C9JTX5_HUMAN,tr|A0A6Q8PH58|A0A6Q8PH58_HUMAN,tr|F6UVQ4|F6UVQ4_HUMAN,tr|F8WB63|F8WB63_HUMAN,tr|I3L1U9|I3L1U9_HUMAN,tr|A0A2R8Y793|A0A2R8Y793_HUMAN,tr|I3L4N8|I3L4N8_HUMAN,tr|C9JUM1|C9JUM1_HUMAN,tr|F8WCH0|F8WCH0_HUMAN,tr|C9JZR7|C9JZR7_HUMAN,tr|C9JFL5|C9JFL5_HUMAN,tr|A0A2R8YGF8|A0A2R8YGF8_HUMAN,tr|A6NL76|A6NL76_HUMAN" 32 1197.6982 2.28 145412 14996 3 1197.698243 400.24 POTE ankyrin domain family member E OS=Homo sapiens OX=9606 GN=POTEE PE=2 SV=3 12 2760.8 - 188234 - - - 0.0142 - 1.931 0.457 - 112.7 1 2 0 0 11 0 0 0 1.21E+07 5.29E+06 - - - 5.5045 0.9997 221125_WJC_METTL3_EV_vs_WT_F10.15002.15002.3 5.33E-07 14/60 K.ILDSVGIEADDDRLNK.V sp|P05387|RLA2_HUMAN 1 1771.8952 1.28 145416 15002 3 1771.898217 591.639 60S acidic ribosomal protein P2 OS=Homo sapiens OX=9606 GN=RPLP2 PE=1 SV=1 4.04 2761.6 - 372716 - - - 1.6982 - 2.81 0.451 - 199.6 1 2 1 0.003 16 0 0 0 6.99E+06 5.48E+06 - - - 6.2184 1 221125_WJC_METTL3_EV_vs_WT_F10.15006.15006.3 5.14E-08 23/72 R.VIHLSNLPHSGYSDSAVLK[136.11].L "sp|P43243|MATR3_HUMAN,tr|B3KM87|B3KM87_HUMAN,tr|A8MXP9|A8MXP9_HUMAN,tr|D6RBK5|D6RBK5_HUMAN,tr|A0A0R4J2E8|A0A0R4J2E8_HUMAN,tr|H0Y8T4|H0Y8T4_HUMAN,tr|D6REM6|D6REM6_HUMAN" 7 2044.0833 1.67 145418 15006 3 2044.089599 682.3684 Matrin-3 OS=Homo sapiens OX=9606 GN=MATR3 PE=1 SV=2 6.89 2762.1 - 1.15E+06 - - - 3.0865 - 3.714 0.563 - 706.9 1 2 0 0.0063 19 0 0 0 3.69E+07 2.21E+07 - - - 8.0387 0.9999 221125_WJC_METTL3_EV_vs_WT_F10.15007.15007.4 0.000137 Nov-96 K.GYPHLC[160.03]SIC[160.03]DLPVHSNK[136.11].E "sp|P43243|MATR3_HUMAN,tr|A8MXP9|A8MXP9_HUMAN,tr|D6R991|D6R991_HUMAN,tr|A0A0R4J2E8|A0A0R4J2E8_HUMAN,tr|H0Y8T4|H0Y8T4_HUMAN,tr|D6REM6|D6REM6_HUMAN" 6 2003.9437 1.35 145419 15007 4 2003.947444 501.9932 Matrin-3 OS=Homo sapiens OX=9606 GN=MATR3 PE=1 SV=2 6.9 2762.3 - 251827 - - - 1.8673 - 1.855 0.473 - 63.7 1 2 0 0.0037 17 0 0 0 3.17E+07 2.34E+07 - - - 3.5565 0.9986 221125_WJC_METTL3_EV_vs_WT_F10.15013.15013.3 0.00316 Aug-52 K.AQIHDLVLVGGSTR.L "sp|P0DMV8|HS71A_HUMAN,sp|P0DMV9|HS71B_HUMAN,tr|V9GZ37|V9GZ37_HUMAN,tr|A0A0G2JIW1|A0A0G2JIW1_HUMAN" 4 1464.8049 0.34 145422 15013 3 1464.806091 489.2756 Heat shock 70 kDa protein 1A OS=Homo sapiens OX=9606 GN=HSPA1A PE=1 SV=1 6.79 2763.1 - 144169 - - - 0.8295 - 1.647 0.289 - 91.5 1 2 0 0.0012 14 0 0 0 8.02E+06 2.39E+07 - - - 3.0877 1 221125_WJC_METTL3_EV_vs_WT_F10.15017.15017.3 1.08E-07 15/80 R.R[166.11]VNSASSSNPPAEVDPDTILK[136.11].A "sp|Q9BY77|PDIP3_HUMAN,tr|F6VRR5|F6VRR5_HUMAN" 2 2214.1247 2.13 145423 15017 3 2214.127394 739.0488 Polymerase delta-interacting protein 3 OS=Homo sapiens OX=9606 GN=POLDIP3 PE=1 SV=2 4.56 2763.6 - 210376 - - - 1.2122 - 3.001 0.568 - 199.3 1 2 0 0.0027 21 0 0 0 2.74E+07 1.29E+07 - - - 7.5066 1 221125_WJC_METTL3_EV_vs_WT_F10.15019.15019.4 1.50E-07 18/114 K.R[166.11]GLLQDDAHPTLVTYADHSK[136.11].L "sp|Q86U44|MTA70_HUMAN,tr|F5H6D8|F5H6D8_HUMAN,tr|H0YFV6|H0YFV6_HUMAN,tr|B4DTN4|B4DTN4_HUMAN" 4 2254.1461 0.02 145425 15019 4 2254.149853 564.5438 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 5.99 2763.9 - 381985 - - - 1.6583 - 3.317 0.503 - 213 1 2 0 0.0037 20 0 0 0 1.21E+06 6.06E+07 - - - 4.0039 1 221125_WJC_METTL3_EV_vs_WT_F10.15025.15025.3 1.39E-07 17/80 R.RVNSASSSNPPAEVDPDTILK.A "sp|Q9BY77|PDIP3_HUMAN,tr|F6VRR5|F6VRR5_HUMAN" 2 2196.1022 2.15 145427 15025 3 2196.104856 733.0414 Polymerase delta-interacting protein 3 OS=Homo sapiens OX=9606 GN=POLDIP3 PE=1 SV=2 4.56 2764.7 - 448067 - - - 1.1912 - 3.149 0.565 - 198.8 1 2 0 0.0026 21 0 0 0 2.77E+07 1.29E+07 - - - 7.5886 0.9989 221125_WJC_METTL3_EV_vs_WT_F10.15026.15026.3 0.026 Jul-40 R.AVFPSIVGR[166.11]PR[166.11].Q "sp|Q6S8J3|POTEE_HUMAN,sp|P63261|ACTG_HUMAN,sp|P68133|ACTS_HUMAN,sp|P62736|ACTA_HUMAN,sp|Q9BYX7|ACTBM_HUMAN,sp|P68032|ACTC_HUMAN,sp|P60709|ACTB_HUMAN,sp|P63267|ACTH_HUMAN,sp|A5A3E0|POTEF_HUMAN,sp|P0CG38|POTEI_HUMAN,tr|A0A804GS07|A0A804GS07_HUMAN,tr|I3L3I0|I3L3I0_HUMAN,tr|G5E9R0|G5E9R0_HUMAN,tr|E7EVS6|E7EVS6_HUMAN,tr|B8ZZJ2|B8ZZJ2_HUMAN,tr|J3KT65|J3KT65_HUMAN,tr|I3L3R2|I3L3R2_HUMAN,tr|K7EM38|K7EM38_HUMAN,tr|F6QUT6|F6QUT6_HUMAN,tr|C9JTX5|C9JTX5_HUMAN,tr|A0A6Q8PH58|A0A6Q8PH58_HUMAN,tr|F6UVQ4|F6UVQ4_HUMAN,tr|F8WB63|F8WB63_HUMAN,tr|I3L1U9|I3L1U9_HUMAN,tr|A0A2R8Y793|A0A2R8Y793_HUMAN,tr|I3L4N8|I3L4N8_HUMAN,tr|C9JUM1|C9JUM1_HUMAN,tr|F8WCH0|F8WCH0_HUMAN,tr|C9JZR7|C9JZR7_HUMAN,tr|C9JFL5|C9JFL5_HUMAN,tr|A0A2R8YGF8|A0A2R8YGF8_HUMAN,tr|A6NL76|A6NL76_HUMAN" 32 1217.7148 2.28 145428 15026 3 1217.715008 406.9122 POTE ankyrin domain family member E OS=Homo sapiens OX=9606 GN=POTEE PE=2 SV=3 12 2764.9 - 124260 - - - 0.1987 - 1.56 0.308 - 80.9 1 2 0 0.0002 11 0 0 0 1.21E+07 5.29E+06 - - - 3.2371 0.9999 221125_WJC_METTL3_EV_vs_WT_F10.15028.15028.4 0.000146 Nov-96 K.KRGFAFVTFDDHDSVDK.L "sp|Q32P51|RA1L2_HUMAN,sp|P09651|ROA1_HUMAN,tr|A0A7I2YQX9|A0A7I2YQX9_HUMAN,tr|F8VZ49|F8VZ49_HUMAN,tr|A0A7I2V3R8|A0A7I2V3R8_HUMAN,tr|F8VTQ5|F8VTQ5_HUMAN,tr|F8W6I7|F8W6I7_HUMAN,tr|H0YH80|H0YH80_HUMAN,tr|A0A7I2V2L6|A0A7I2V2L6_HUMAN,tr|A0A7I2V3W0|A0A7I2V3W0_HUMAN,tr|A0A7I2V5U9|A0A7I2V5U9_HUMAN,tr|A0A2R8Y4L2|A0A2R8Y4L2_HUMAN" 12 1982.9486 0.91 145430 15028 4 1982.950272 496.7444 Heterogeneous nuclear ribonucleoprotein A1-like 2 OS=Homo sapiens OX=9606 GN=HNRNPA1L2 PE=2 SV=2 5.36 2765.1 - 157719 - - - 0.823 - 2.489 0.527 - 95.5 1 2 1 0.0016 17 0 0 0 3.82E+06 4.21E+06 - - - 4.1292 0.9994 221125_WJC_METTL3_EV_vs_WT_F10.15032.15032.4 6.32E-06 16/168 K.TTGTPPDSSLVTYELHSRPEQDKFSQAAK.V "sp|Q13561|DCTN2_HUMAN,tr|H0YI98|H0YI98_HUMAN,tr|A8K8J9|A8K8J9_HUMAN,tr|A0A7I2V5R4|A0A7I2V5R4_HUMAN,tr|F8W1I6|F8W1I6_HUMAN,tr|A0A7I2V4H4|A0A7I2V4H4_HUMAN,tr|A0A7I2V390|A0A7I2V390_HUMAN,tr|A0A7I2V4Y9|A0A7I2V4Y9_HUMAN,tr|F8VW18|F8VW18_HUMAN" 9 3189.5578 4.66 145431 15032 4 3189.561984 798.3967 Dynactin subunit 2 OS=Homo sapiens OX=9606 GN=DCTN2 PE=1 SV=4 5.45 2765.7 - 232637 - - - 1.3005 - 2.631 0.398 - 70.4 1 2 1 0.0041 29 0 0 0 1.20E+07 2.58E+06 - - - 2.9872 0.9328 221125_WJC_METTL3_EV_vs_WT_F10.15034.15034.4 0.0484 9/186 D.SPVPTAPTSGGPK[136.11]PSTASAVPELATDPELEK[136.11]K[136.11].L "sp|Q86U44|MTA70_HUMAN,tr|B4E349|B4E349_HUMAN,tr|F5H6D8|F5H6D8_HUMAN,tr|B4DTN4|B4DTN4_HUMAN" 4 3182.6773 0 145433 15034 4 3182.675191 796.6766 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 4.87 2766 - 284188 - - - -0.6595 - 2.331 0.321 - 24.9 1 1 0 -0.0021 32 0 0 0 7.57E+05 1.54E+09 - - - 2.2749 1 221125_WJC_METTL3_EV_vs_WT_F10.15043.15043.4 8.65E-10 14/174 K.AAVSHWQQQSYLDSGIHSGATTTAPSLSGK.G "sp|P35222|CTNB1_HUMAN,tr|A0A2R8Y5C3|A0A2R8Y5C3_HUMAN,tr|A0A2R8YCH5|A0A2R8YCH5_HUMAN,tr|A0A2R8Y543|A0A2R8Y543_HUMAN,tr|A0A2R8Y750|A0A2R8Y750_HUMAN,tr|B4DGU4|B4DGU4_HUMAN,tr|C9IZ65|C9IZ65_HUMAN,tr|A0A2R8Y5A3|A0A2R8Y5A3_HUMAN,tr|A0A2R8Y804|A0A2R8Y804_HUMAN,tr|A0A2R8Y5Z1|A0A2R8Y5Z1_HUMAN,tr|A0A2R8Y7Z0|A0A2R8Y7Z0_HUMAN" 11 3084.4901 1.18 145440 15043 4 3084.492436 772.1298 Catenin beta-1 OS=Homo sapiens OX=9606 GN=CTNNB1 PE=1 SV=1 6.96 2767.2 - 218498 - - - 0.7603 - 3.206 0.556 - 71.3 1 2 0 0.0023 30 0 0 0 4.28E+06 3.62E+06 - - - 4.4213 0.9531 221125_WJC_METTL3_EV_vs_WT_F10.15046.15046.3 2.18 Jun-92 K.ELQQAQTTRPESTQIQPQPGFC[160.03]IK.T "sp|Q9NWS0|PIHD1_HUMAN,tr|M0QYF4|M0QYF4_HUMAN,tr|M0QXD5|M0QXD5_HUMAN,tr|M0R3A8|M0R3A8_HUMAN,tr|M0R0J2|M0R0J2_HUMAN,tr|M0QYA2|M0QYA2_HUMAN" 6 2784.3865 2.36 145441 15046 3 2784.387695 929.1361 PIH1 domain-containing protein 1 OS=Homo sapiens OX=9606 GN=PIH1D1 PE=1 SV=1 6.23 2767.6 - 195475 - - - 0.4371 - 1.387 0.143 - 22.4 1 2 0 0.0012 24 0 0 0 8.51E+06 3.61E+06 - - - 0.8938 0.989 221125_WJC_METTL3_EV_vs_WT_F10.15051.15051.2 0.306 12-May K.FASFIDK.V "sp|Q86Y46|K2C73_HUMAN,sp|Q7RTS7|K2C74_HUMAN,sp|Q9NSB2|KRT84_HUMAN,sp|P48668|K2C6C_HUMAN,sp|Q3SY84|K2C71_HUMAN,sp|P05787|K2C8_HUMAN,sp|Q01546|K22O_HUMAN,sp|P19013|K2C4_HUMAN,sp|Q7Z794|K2C1B_HUMAN,sp|Q8N1N4|K2C78_HUMAN,sp|P12035|K2C3_HUMAN,sp|P04264|K2C1_HUMAN,sp|P04259|K2C6B_HUMAN,sp|P13647|K2C5_HUMAN,sp|P35908|K22E_HUMAN,sp|Q14CN4|K2C72_HUMAN,sp|P08729|K2C7_HUMAN,sp|O95678|K2C75_HUMAN,sp|Q5XKE5|K2C79_HUMAN,sp|P02538|K2C6A_HUMAN,tr|F8VUG2|F8VUG2_HUMAN,tr|F8W0C6|F8W0C6_HUMAN,tr|F8W1U3|F8W1U3_HUMAN,tr|H0YHD9|H0YHD9_HUMAN,tr|F8W1S1|F8W1S1_HUMAN,tr|F8VS61|F8VS61_HUMAN" 26 826.4225 83.59 145443 15051 2 826.423495 414.2185 "Keratin, type II cytoskeletal 73 OS=Homo sapiens OX=9606 GN=KRT73 PE=1 SV=1" 5.84 2768.3 - 245569 - - - 1.1979 - 1.15 0.18 - 52.4 1 2 0 0.001 7 0 0 0 1.17E+07 1.40E+05 - - - 0.813 0.9934 221125_WJC_METTL3_EV_vs_WT_F10.15053.15053.4 8.71E-06 10/114 R.DC[160.03]QLNAHKDHQYQFLEDAVR.N "sp|Q13263|TIF1B_HUMAN,tr|M0R2I3|M0R2I3_HUMAN,tr|M0R3C0|M0R3C0_HUMAN" 3 2486.1397 0.9 145444 15053 4 2486.145979 622.5422 Transcription intermediary factor 1-beta OS=Homo sapiens OX=9606 GN=TRIM28 PE=1 SV=5 5.26 2768.5 - 274744 - - - 2.5232 - 2.135 0.31 - 75.1 1 2 1 0.0063 20 0 0 0 5.83E+07 6.48E+07 - - - 2.1761 0.9996 221125_WJC_METTL3_EV_vs_WT_F10.15057.15057.4 1.64E-06 12/114 R.DC[160.03]QLNAHK[136.11]DHQYQFLEDAVR[166.11].N "sp|Q13263|TIF1B_HUMAN,tr|M0R2I3|M0R2I3_HUMAN,tr|M0R3C0|M0R3C0_HUMAN" 3 2504.1622 0.9 145446 15057 4 2504.168788 627.0478 Transcription intermediary factor 1-beta OS=Homo sapiens OX=9606 GN=TRIM28 PE=1 SV=5 5.26 2769.1 - 358111 - - - 2.6404 - 2.411 0.481 - 106.7 1 2 1 0.0066 20 0 0 0 5.83E+07 6.48E+07 - - - 3.705 1 221125_WJC_METTL3_EV_vs_WT_F10.15063.15063.4 5.20E-09 16/174 K.AAVSHWQQQSYLDSGIHSGATTTAPSLSGK[136.11].G "sp|P35222|CTNB1_HUMAN,tr|A0A2R8Y5C3|A0A2R8Y5C3_HUMAN,tr|A0A2R8YCH5|A0A2R8YCH5_HUMAN,tr|A0A2R8Y543|A0A2R8Y543_HUMAN,tr|A0A2R8Y750|A0A2R8Y750_HUMAN,tr|B4DGU4|B4DGU4_HUMAN,tr|C9IZ65|C9IZ65_HUMAN,tr|A0A2R8Y5A3|A0A2R8Y5A3_HUMAN,tr|A0A2R8Y804|A0A2R8Y804_HUMAN,tr|A0A2R8Y5Z1|A0A2R8Y5Z1_HUMAN,tr|A0A2R8Y7Z0|A0A2R8Y7Z0_HUMAN" 11 3092.5043 1.18 145448 15063 4 3092.507528 774.1333 Catenin beta-1 OS=Homo sapiens OX=9606 GN=CTNNB1 PE=1 SV=1 6.96 2770 - 219375 - - - 1.0467 - 3.112 0.612 - 105.1 1 2 0 0.0032 30 0 0 0 4.28E+06 3.62E+06 - - - 4.8993 0.9966 221125_WJC_METTL3_EV_vs_WT_F10.15066.15066.4 3.92E-05 9/108 K.VTEGLTDVILYHQPDDK[136.11]K[136.11]K[136.11].N "sp|O60506|HNRPQ_HUMAN,tr|A0A7I2YQV8|A0A7I2YQV8_HUMAN,tr|A0A7I2YQN2|A0A7I2YQN2_HUMAN,tr|A0A7I2V5Q6|A0A7I2V5Q6_HUMAN,tr|A0A7I2V4Z0|A0A7I2V4Z0_HUMAN,tr|B7Z645|B7Z645_HUMAN,tr|A0A7I2V2F2|A0A7I2V2F2_HUMAN,tr|A0A7I2V346|A0A7I2V346_HUMAN,tr|A0A7I2V309|A0A7I2V309_HUMAN" 9 2222.2009 1.24 145450 15066 4 2222.208682 556.5575 Heterogeneous nuclear ribonucleoprotein Q OS=Homo sapiens OX=9606 GN=SYNCRIP PE=1 SV=2 5.43 2770.3 - 138788 - - - 3.5024 - 2.201 0.384 - 49 1 2 1 0.0078 19 0 0 0 1.90E+07 1.54E+07 - - - 2.8331 0.9999 221125_WJC_METTL3_EV_vs_WT_F10.15074.15074.4 7.02E-05 11/144 K.VETVHC[160.03]SAC[160.03]SVYIPALHSSVQQHLK.S "sp|Q5BKZ1|ZN326_HUMAN,tr|A0A0A0MRN4|A0A0A0MRN4_HUMAN" 2 2849.3953 1.67 145453 15074 4 2849.398045 713.3561 DBIRD complex subunit ZNF326 OS=Homo sapiens OX=9606 GN=ZNF326 PE=1 SV=2 6.98 2771.4 - 209156 - - - 0.9742 - 2.198 0.446 - 44.2 1 2 0 0.0028 25 0 0 0 1.00E+07 6.01E+06 - - - 3.3578 0.9999 221125_WJC_METTL3_EV_vs_WT_F10.15078.15078.3 3.30E-08 Nov-76 R.DC[160.03]QLNAHK[136.11]DHQYQFLEDAVR[166.11].N "sp|Q13263|TIF1B_HUMAN,tr|M0R2I3|M0R2I3_HUMAN,tr|M0R3C0|M0R3C0_HUMAN" 3 2504.1622 0.83 145455 15078 3 2504.162877 835.728 Transcription intermediary factor 1-beta OS=Homo sapiens OX=9606 GN=TRIM28 PE=1 SV=5 5.26 2771.8 - 177624 - - - 0.2799 - 2.403 0.628 - 146.9 1 2 1 0.0007 20 0 0 0 5.25E+06 6.34E+06 - - - 7.6683 0.9998 221125_WJC_METTL3_EV_vs_WT_F10.15083.15083.3 3.42E-07 14/76 R.DC[160.03]QLNAHKDHQYQFLEDAVR.N "sp|Q13263|TIF1B_HUMAN,tr|M0R2I3|M0R2I3_HUMAN,tr|M0R3C0|M0R3C0_HUMAN" 3 2486.1397 0.83 145457 15083 3 2486.140482 829.7205 Transcription intermediary factor 1-beta OS=Homo sapiens OX=9606 GN=TRIM28 PE=1 SV=5 5.26 2772.6 - 169280 - - - 0.3121 - 2.036 0.522 - 98.2 1 2 1 0.0008 20 0 0 0 5.25E+06 6.34E+06 - - - 6.0844 0.9965 221125_WJC_METTL3_EV_vs_WT_F10.15087.15087.3 2.78E-06 Dec-60 L.QDDAHPTLVTYADHSK[136.11].L "sp|Q86U44|MTA70_HUMAN,tr|F5H6D8|F5H6D8_HUMAN,tr|H0YFV6|H0YFV6_HUMAN,tr|B4DTN4|B4DTN4_HUMAN" 4 1804.8471 0.03 145459 15087 3 1804.848144 602.623 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 5.13 2773.1 - 392004 - - - 0.5552 - 2.383 0.504 - 187.5 1 1 0 0.001 16 0 0 0 2.16E+06 7.02E+07 - - - 6.3869 0.9999 221125_WJC_METTL3_EV_vs_WT_F10.15088.15088.2 1.59E-06 Sep-36 R.GLLQDDAHPTLVTYADHSK[136.11].L "sp|Q86U44|MTA70_HUMAN,tr|F5H6D8|F5H6D8_HUMAN,tr|H0YFV6|H0YFV6_HUMAN,tr|B4DTN4|B4DTN4_HUMAN" 4 2088.0367 0.001 145460 15088 2 2088.038257 1045.0256 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 5.13 2773.2 - 150263 - - - 0.7299 - 1.98 0.599 - 141.3 1 2 0 0.0015 19 0 0 0 0.00E+00 3.61E+07 - - - 5.1442 0.9985 221125_WJC_METTL3_EV_vs_WT_F10.15095.15095.3 2.16E-08 18/64 L.LQDDAHPTLVTYADHSK[136.11].L "sp|Q86U44|MTA70_HUMAN,tr|F5H6D8|F5H6D8_HUMAN,tr|H0YFV6|H0YFV6_HUMAN,tr|B4DTN4|B4DTN4_HUMAN" 4 1917.9312 0 145462 15095 3 1917.928847 640.3177 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 5.13 2774.2 - 2.00E+06 - - - -1.23 - 3.087 0.575 - 374.7 1 1 0 -0.0024 17 0 0 0 6.35E+05 1.43E+08 - - - 7.7977 0.997 221125_WJC_METTL3_EV_vs_WT_F10.15099.15099.4 0.000191 8/114 K.HAAENPGKYNILGTNTIMDK.M "sp|Q00839|HNRPU_HUMAN,tr|A0A1W2PQL0|A0A1W2PQL0_HUMAN,tr|A0A1W2PPL4|A0A1W2PPL4_HUMAN,tr|A0A1W2PQ74|A0A1W2PQ74_HUMAN,tr|Q5RI18|Q5RI18_HUMAN,tr|A0A1W2PP35|A0A1W2PP35_HUMAN,tr|A0A1W2PPS1|A0A1W2PPS1_HUMAN,tr|A0A1W2PRZ7|A0A1W2PRZ7_HUMAN,tr|A0A1W2PPH7|A0A1W2PPH7_HUMAN,tr|A0A1W2PQD4|A0A1W2PQD4_HUMAN,tr|A0A1W2PP34|A0A1W2PP34_HUMAN,tr|A0A1X7SBS1|A0A1X7SBS1_HUMAN" 12 2186.079 1.28 145464 15099 4 2186.073266 547.527 Heterogeneous nuclear ribonucleoprotein U OS=Homo sapiens OX=9606 GN=HNRNPU PE=1 SV=6 6.75 2774.7 - 173946 - - - -2.6243 - 2.222 0.353 - 46 1 2 1 -0.0057 20 0 0 0 1.02E+07 8.01E+06 - - - 2.5638 0.9998 221125_WJC_METTL3_EV_vs_WT_F10.15103.15103.4 0.000151 17/108 K.VTEGLTDVILYHQPDDKKK.N "sp|O60506|HNRPQ_HUMAN,tr|A0A7I2YQV8|A0A7I2YQV8_HUMAN,tr|A0A7I2YQN2|A0A7I2YQN2_HUMAN,tr|A0A7I2V5Q6|A0A7I2V5Q6_HUMAN,tr|A0A7I2V4Z0|A0A7I2V4Z0_HUMAN,tr|B7Z645|B7Z645_HUMAN,tr|A0A7I2V2F2|A0A7I2V2F2_HUMAN,tr|A0A7I2V346|A0A7I2V346_HUMAN,tr|A0A7I2V309|A0A7I2V309_HUMAN" 9 2198.1583 1.24 145466 15103 4 2198.15546 550.5469 Heterogeneous nuclear ribonucleoprotein Q OS=Homo sapiens OX=9606 GN=SYNCRIP PE=1 SV=2 5.43 2775.2 - 619083 - - - -1.2915 - 2.89 0.484 - 149.8 1 2 1 -0.0028 19 0 0 0 1.92E+07 1.54E+07 - - - 3.797 0.9982 221125_WJC_METTL3_EV_vs_WT_F10.15117.15117.3 3.29E-08 14/56 Q.DDAHPTLVTYADHSK[136.11].L "sp|Q86U44|MTA70_HUMAN,tr|F5H6D8|F5H6D8_HUMAN,tr|H0YFV6|H0YFV6_HUMAN,tr|B4DTN4|B4DTN4_HUMAN" 4 1676.7886 0.03 145471 15117 3 1676.785968 559.9368 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 5.13 2777.1 - 549768 - - - -1.5482 - 2.768 0.589 - 286 1 1 0 -0.0026 15 0 0 0 4.76E+05 1.65E+07 - - - 7.7627 0.9924 221125_WJC_METTL3_EV_vs_WT_F10.15125.15125.4 6.16E-05 11/102 G.LLQDDAHPTLVTYADHSK[136.11].L "sp|Q86U44|MTA70_HUMAN,tr|F5H6D8|F5H6D8_HUMAN,tr|H0YFV6|H0YFV6_HUMAN,tr|B4DTN4|B4DTN4_HUMAN" 4 2031.0153 0.23 145475 15125 4 2031.013466 508.7611 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 5.13 2778.1 - 385050 - - - -0.8882 - 2.131 0.459 - 79.5 1 1 0 -0.0018 18 0 0 0 1.50E+06 6.64E+06 - - - 3.4798 0.9922 221125_WJC_METTL3_EV_vs_WT_F10.15133.15133.3 7.60E-08 17/124 D.SPVPTAPTSGGPK[136.11]PSTASAVPELATDPELEK[136.11]K[136.11].L "sp|Q86U44|MTA70_HUMAN,tr|B4E349|B4E349_HUMAN,tr|F5H6D8|F5H6D8_HUMAN,tr|B4DTN4|B4DTN4_HUMAN" 4 3182.6773 0.001 145478 15133 3 3182.667061 1061.8997 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 4.87 2779.2 - 1.46E+06 - - - -3.214 - 3.062 0.555 - 117.2 1 1 0 -0.0102 32 0 0 0 0.00E+00 5.58E+07 - - - 7.2994 0.9996 221125_WJC_METTL3_EV_vs_WT_F10.15142.15142.4 0.000486 14/192 R.SDSPVPTAPTSGGPK[136.11]PSTASAVPELATDPELEK[136.11].K "sp|Q86U44|MTA70_HUMAN,tr|B4E349|B4E349_HUMAN,tr|F5H6D8|F5H6D8_HUMAN,tr|B4DTN4|B4DTN4_HUMAN" 4 3248.6271 0.16 145483 15142 4 3248.623259 813.1641 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 4.18 2780.3 - 793807 - - - -1.1817 - 2.216 0.347 - 81.9 1 2 0 -0.0038 33 0 0 0 2.30E+07 1.45E+08 - - - 2.484 1 221125_WJC_METTL3_EV_vs_WT_F10.15164.15164.3 7.74E-09 18/72 R.GLLQDDAHPTLVTYADHSK[136.11].L "sp|Q86U44|MTA70_HUMAN,tr|F5H6D8|F5H6D8_HUMAN,tr|H0YFV6|H0YFV6_HUMAN,tr|B4DTN4|B4DTN4_HUMAN" 4 2088.0367 0.01 145492 15164 3 2088.034446 697.0195 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 5.13 2783.3 - 1.44E+07 - - - -1.0953 - 3.381 0.653 - 343.4 1 2 0 -0.0023 19 0 0 0 3.66E+07 2.54E+09 - - - 8.8125 0.9987 221125_WJC_METTL3_EV_vs_WT_F10.15175.15175.3 0.000306 12/128 K.LASVPAGGAVAVSAAPGSAAPAAGSAPAAAEEK.K "sp|P05387|RLA2_HUMAN,tr|H0YDD8|H0YDD8_HUMAN" 2 2773.4246 2.13 145496 15175 3 2773.434113 925.4822 60S acidic ribosomal protein P2 OS=Homo sapiens OX=9606 GN=RPLP2 PE=1 SV=1 4.53 2784.8 - 216724 - - - 3.4167 - 2.117 0.371 - 65.4 1 2 0 0.0095 33 0 0 0 8.48E+06 3.98E+06 - - - 4.3991 1 221125_WJC_METTL3_EV_vs_WT_F10.15178.15178.4 8.64E-08 14/108 R.GLLQDDAHPTLVTYADHSK[136.11].L "sp|Q86U44|MTA70_HUMAN,tr|F5H6D8|F5H6D8_HUMAN,tr|H0YFV6|H0YFV6_HUMAN,tr|B4DTN4|B4DTN4_HUMAN" 4 2088.0367 0.02 145497 15178 4 2088.034554 523.0165 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 5.13 2785.2 - 9.10E+06 - - - -1.0436 - 2.797 0.599 - 179.2 1 2 0 -0.0022 19 0 0 0 1.22E+08 5.05E+09 - - - 4.787 1 221125_WJC_METTL3_EV_vs_WT_F10.15188.15188.3 6.56E-10 20/84 K.DHTPSQELALTQSVGGDSSADR[166.11].L "sp|Q86U44|MTA70_HUMAN,tr|H0YFV6|H0YFV6_HUMAN" 2 2280.0494 0.02 145503 15188 3 2280.042271 761.0237 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 4.22 2786.6 - 221192 - - - -3.1122 - 3.778 0.67 - 373.8 1 2 0 -0.0071 22 0 0 0 2.53E+05 1.22E+07 - - - 9.1592 1 221125_WJC_METTL3_EV_vs_WT_F10.15189.15189.4 1.66E-07 17/120 R.LHNFHQLSAPQPC[160.03]FTFSHPNR.D "sp|O14744|ANM5_HUMAN,tr|H0YJD3|H0YJD3_HUMAN,tr|H7BZ44|H7BZ44_HUMAN" 3 2534.2026 2.18 145504 15189 4 2534.20591 634.5579 Protein arginine N-methyltransferase 5 OS=Homo sapiens OX=9606 GN=PRMT5 PE=1 SV=4 8.28 2786.7 - 292879 - - - 1.3136 - 3.712 0.599 - 234 1 2 0 0.0033 21 0 0 0 2.26E+07 1.04E+07 - - - 4.8724 1 221125_WJC_METTL3_EV_vs_WT_F10.15194.15194.3 1.51E-14 22/128 R.GGGGYGGSGDGYNGFGNDGGYGGGGPGYSGGSR.G sp|P09651|ROA1_HUMAN 1 2873.1298 1.77 145507 15194 3 2873.129917 958.7172 Heterogeneous nuclear ribonucleoprotein A1 OS=Homo sapiens OX=9606 GN=HNRNPA1 PE=1 SV=5 4.21 2787.3 - 440471 - - - 0.039 - 3.578 0.838 - 334.8 1 2 0 0.0001 33 0 0 0 2.44E+07 1.38E+07 - - - 10.8157 1 221125_WJC_METTL3_EV_vs_WT_F10.15195.15195.3 1.62E-10 17/128 R.GGGGYGGSGDGYNGFGNDGGYGGGGPGYSGGSR[166.11].G sp|P09651|ROA1_HUMAN 1 2883.1381 1.77 145508 15195 3 2883.140603 962.0533 Heterogeneous nuclear ribonucleoprotein A1 OS=Homo sapiens OX=9606 GN=HNRNPA1 PE=1 SV=5 4.21 2787.4 - 430051 - - - 0.8768 - 3.395 0.835 - 193 1 2 0 0.0025 33 0 0 0 2.44E+07 1.38E+07 - - - 10.6608 1 221125_WJC_METTL3_EV_vs_WT_F10.15200.15200.4 1.60E-08 23/180 K.TAR[166.11]PFGAPPPADSAPQQNGQPLR[166.11]PLVPDASK[136.11].Q "sp|Q9NR12|PDLI7_HUMAN,tr|D6RF83|D6RF83_HUMAN,tr|H7BYK4|H7BYK4_HUMAN,tr|D6RH06|D6RH06_HUMAN" 4 3207.6783 46.2 145510 15200 4 3207.674945 802.9269 PDZ and LIM domain protein 7 OS=Homo sapiens OX=9606 GN=PDLIM7 PE=1 SV=1 8.41 2788 - 480681 - - - -1.0568 - 3.891 0.571 - 182.9 1 2 0 -0.0034 31 0 0 0 1.33E+09 2.89E+07 - - - 4.608 0.9998 221125_WJC_METTL3_EV_vs_WT_F10.15203.15203.3 2.65E-07 14/128 K.LASVPAGGAVAVSAAPGSAAPAAGSAPAAAEEK[136.11].K "sp|P05387|RLA2_HUMAN,tr|H0YDD8|H0YDD8_HUMAN" 2 2781.4388 2.13 145512 15203 3 2781.42662 928.1536 60S acidic ribosomal protein P2 OS=Homo sapiens OX=9606 GN=RPLP2 PE=1 SV=1 4.53 2788.4 - 246458 - - - -4.3923 - 2.742 0.542 - 100.2 1 2 0 -0.0122 33 0 0 0 8.48E+06 3.98E+06 - - - 6.9 0.9958 221125_WJC_METTL3_EV_vs_WT_F10.15209.15209.3 5.95E-06 11/128 R.SDSPVPTAPTSGGPK[136.11]PSTASAVPELATDPELEK[136.11].K "sp|Q86U44|MTA70_HUMAN,tr|B4E349|B4E349_HUMAN,tr|F5H6D8|F5H6D8_HUMAN,tr|B4DTN4|B4DTN4_HUMAN" 4 3248.6271 0.001 145516 15209 3 3249.635886 1083.883 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 4.18 2789.1 - 297794 - - - 310.5275 - 2.228 0.463 - 56.4 1 2 0 1.0088 33 0 0 0 0.00E+00 5.15E+06 - - - 5.2656 1 221125_WJC_METTL3_EV_vs_WT_F10.15214.15214.3 3.42E-08 15/100 K.NQSPTEAEKPASSSLPSSPPPQLLTR.N "sp|Q99567|NUP88_HUMAN,tr|I3L2W3|I3L2W3_HUMAN" 2 2718.3824 2.6 145518 15214 3 2718.387293 907.1348 Nuclear pore complex protein Nup88 OS=Homo sapiens OX=9606 GN=NUP88 PE=1 SV=2 6.14 2789.8 - 314440 - - - 1.786 - 3.164 0.633 - 148.7 1 2 0 0.0049 26 0 0 0 5.45E+07 2.10E+07 - - - 8.2459 0.9922 221125_WJC_METTL3_EV_vs_WT_F10.15217.15217.4 2.74 6/156 D.GYC[160.03]DKAC[160.03]NNSAC[160.03]DWDGGDC[160.03]SGNSGGSR.Y sp|Q3T906|GNPTA_HUMAN 1 2926.0396 11.92 145520 15217 4 2926.040469 732.5172 N-acetylglucosamine-1-phosphotransferase subunits alpha\beta OS=Homo sapiens OX=9606 GN=GNPTAB PE=1 SV=1 4.14 2790.1 - 430542 - - - 0.3131 - 0.888 0.628 - 14.2 1 1 1 0.0009 27 0 0 0 8.51E+06 7.13E+05 - - - 4.6547 0.9915 221125_WJC_METTL3_EV_vs_WT_F10.15230.15230.4 0.0294 9/108 R.EATSVHDLNDKLENEIANK.D "sp|Q13136|LIPA1_HUMAN,tr|H0YEF9|H0YEF9_HUMAN,tr|E9PJZ7|E9PJZ7_HUMAN,tr|A0A2R8Y7R9|A0A2R8Y7R9_HUMAN" 4 2139.0444 0.75 145527 15230 4 2139.048142 535.7684 Liprin-alpha-1 OS=Homo sapiens OX=9606 GN=PPFIA1 PE=1 SV=1 4.5 2791.9 - 338408 - - - 1.7536 - 1.741 0.281 - 35 1 2 1 0.0038 19 0 0 0 8.83E+06 1.18E+07 - - - 1.8583 0.9919 221125_WJC_METTL3_EV_vs_WT_F10.15232.15232.4 0.0333 Dec-96 R.RAPEEELPPLDPEEIRK.R "sp|Q8IY67|RAVR1_HUMAN,tr|K7EKR9|K7EKR9_HUMAN,tr|E9PAU2|E9PAU2_HUMAN,tr|A0A087WZ13|A0A087WZ13_HUMAN" 4 2017.048 1.03 145529 15232 4 2017.050425 505.2693 Ribonucleoprotein PTB-binding 1 OS=Homo sapiens OX=9606 GN=RAVER1 PE=1 SV=1 4.42 2792.1 - 242169 - - - 1.1923 - 1.722 0.21 - 78.5 1 2 0 0.0024 17 0 0 0 7.52E+06 7.31E+06 - - - 1.2419 1 221125_WJC_METTL3_EV_vs_WT_F10.15236.15236.4 2.94E-10 28/126 R.RDSFDDRGPSLNPVLDYDHGSR.S "sp|P43243|MATR3_HUMAN,tr|A8MXP9|A8MXP9_HUMAN,tr|D6R991|D6R991_HUMAN,tr|A0A0R4J2E8|A0A0R4J2E8_HUMAN,tr|D6REM6|D6REM6_HUMAN" 5 2517.1633 1.29 145530 15236 4 2517.16877 630.2981 Matrin-3 OS=Homo sapiens OX=9606 GN=MATR3 PE=1 SV=2 4.67 2792.7 - 1.03E+06 - - - 2.1818 - 4.469 0.664 - 388.5 1 2 1 0.0055 22 0 0 0 1.65E+08 1.28E+08 - - - 5.4938 1 221125_WJC_METTL3_EV_vs_WT_F10.15241.15241.4 3.30E-09 28/126 R.R[166.11]DSFDDR[166.11]GPSLNPVLDYDHGSR[166.11].S "sp|P43243|MATR3_HUMAN,tr|A8MXP9|A8MXP9_HUMAN,tr|D6R991|D6R991_HUMAN,tr|A0A0R4J2E8|A0A0R4J2E8_HUMAN,tr|D6REM6|D6REM6_HUMAN" 5 2547.1881 1.29 145533 15241 4 2547.189771 637.8043 Matrin-3 OS=Homo sapiens OX=9606 GN=MATR3 PE=1 SV=2 4.67 2793.4 - 1.23E+06 - - - 0.6607 - 4.25 0.641 - 398.2 1 2 1 0.0017 22 0 0 0 1.65E+08 1.28E+08 - - - 5.2782 0.9999 221125_WJC_METTL3_EV_vs_WT_F10.15243.15243.4 2.23E-05 12/180 K.SK[136.11]PELPPGLSPEATAPVTPSR[166.11]PEGGEPGLSK[136.11].T sp|Q9BRP8|PYM1_HUMAN 1 3107.6349 0.87 145535 15243 4 3107.641378 777.916 Partner of Y14 and mago OS=Homo sapiens OX=9606 GN=PYM1 PE=1 SV=1 4.94 2793.6 - 189680 - - - 2.0797 - 2.275 0.493 - 42.1 1 2 0 0.0065 31 0 0 0 3.87E+07 4.44E+07 - - - 3.7651 1 221125_WJC_METTL3_EV_vs_WT_F10.15249.15249.4 6.41E-06 21/114 K.R[166.11]GLLQDDAHPTLVTYADHSK[136.11].L "sp|Q86U44|MTA70_HUMAN,tr|F5H6D8|F5H6D8_HUMAN,tr|H0YFV6|H0YFV6_HUMAN,tr|B4DTN4|B4DTN4_HUMAN" 4 2254.1461 0.02 145537 15249 4 2254.148227 564.5438 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 5.99 2794.4 - 398184 - - - 0.9369 - 3.492 0.523 - 425.3 1 2 0 0.0021 20 0 0 0 1.21E+06 6.04E+07 - - - 4.1957 1 221125_WJC_METTL3_EV_vs_WT_F10.15251.15251.3 1.94E-08 9/100 K.NQSPTEAEK[136.11]PASSSLPSSPPPQLLTR[166.11].N "sp|Q99567|NUP88_HUMAN,tr|I3L2W3|I3L2W3_HUMAN" 2 2736.4049 2.58 145539 15251 3 2736.402446 913.1422 Nuclear pore complex protein Nup88 OS=Homo sapiens OX=9606 GN=NUP88 PE=1 SV=2 6.14 2794.7 - 282517 - - - -0.8997 - 2.288 0.547 - 52.1 1 2 0 -0.0025 26 0 0 0 5.37E+07 2.08E+07 - - - 6.542 0.9999 221125_WJC_METTL3_EV_vs_WT_F10.15254.15254.4 0.000263 13/138 K.K[136.11]PQDLAHTGISSGLIAGSSIQNPK[136.11].V sp|Q6ZU65|UBN2_HUMAN 1 2434.3151 1.29 145542 15254 4 2434.315855 609.586 Ubinuclein-2 OS=Homo sapiens OX=9606 GN=UBN2 PE=1 SV=2 8.6 2795.1 - 170081 - - - 0.3155 - 2.241 0.412 - 73.8 1 2 0 0.0008 24 0 0 0 1.18E+07 9.16E+06 - - - 3.0708 1 221125_WJC_METTL3_EV_vs_WT_F10.15258.15258.4 4.56E-05 14/180 K.SKPELPPGLSPEATAPVTPSRPEGGEPGLSK.T sp|Q9BRP8|PYM1_HUMAN 1 3081.5982 0.79 145544 15258 4 3081.600365 771.4068 Partner of Y14 and mago OS=Homo sapiens OX=9606 GN=PYM1 PE=1 SV=1 4.94 2795.6 - 378493 - - - 0.688 - 2.385 0.49 - 62.3 1 2 0 0.0021 31 0 0 0 2.75E+07 3.49E+07 - - - 3.7545 1 221125_WJC_METTL3_EV_vs_WT_F10.15259.15259.4 7.84E-07 20/126 K.HDGTGGQSIYGDK[136.11]FEDENFDVK[136.11].H sp|P49792|RBP2_HUMAN 1 2473.1005 0.96 145545 15259 4 2473.102755 619.2824 E3 SUMO-protein ligase RanBP2 OS=Homo sapiens OX=9606 GN=RANBP2 PE=1 SV=2 4.23 2795.7 - 576794 - - - 0.9268 - 2.757 0.659 - 154 1 2 1 0.0023 22 0 0 0 2.17E+07 2.27E+07 - - - 5.2931 1 221125_WJC_METTL3_EV_vs_WT_F10.15263.15263.4 3.61E-10 21/126 K.HDGTGGQSIYGDKFEDENFDVK.H sp|P49792|RBP2_HUMAN 1 2457.0721 0.96 145547 15263 4 2457.071508 615.2753 E3 SUMO-protein ligase RanBP2 OS=Homo sapiens OX=9606 GN=RANBP2 PE=1 SV=2 4.23 2796.3 - 514030 - - - -0.2259 - 3.195 0.668 - 387.1 1 2 1 -0.0006 22 0 0 0 2.17E+07 2.27E+07 - - - 5.4202 1 221125_WJC_METTL3_EV_vs_WT_F10.15264.15264.4 5.32E-16 29/138 K.TAHNSEADLEESFNEHELEPSSPK.S sp|Q8IWS0|PHF6_HUMAN 1 2696.1838 0.71 145548 15264 4 2696.189288 675.0532 PHD finger protein 6 OS=Homo sapiens OX=9606 GN=PHF6 PE=1 SV=1 4.3 2796.4 - 794792 - - - 2.0362 - 5.135 0.739 - 688.6 1 2 0 0.0055 24 0 0 0 2.85E+07 4.04E+07 - - - 6.1819 0.9999 221125_WJC_METTL3_EV_vs_WT_F10.15267.15267.3 2.28E-08 Sep-84 K.HDGTGGQSIYGDKFEDENFDVK.H sp|P49792|RBP2_HUMAN 1 2457.0721 2.08 145549 15267 3 2457.077262 820.0313 E3 SUMO-protein ligase RanBP2 OS=Homo sapiens OX=9606 GN=RANBP2 PE=1 SV=2 4.23 2796.8 - 246029 - - - 2.1159 - 2.14 0.649 - 77.2 1 2 1 0.0052 22 0 0 0 5.16E+06 2.48E+06 - - - 7.578 0.9993 221125_WJC_METTL3_EV_vs_WT_F10.15269.15269.4 1.76E-06 17/138 K.KPQDLAHTGISSGLIAGSSIQNPK.V sp|Q6ZU65|UBN2_HUMAN 1 2418.2867 1.29 145550 15269 4 2418.298131 605.5789 Ubinuclein-2 OS=Homo sapiens OX=9606 GN=UBN2 PE=1 SV=2 8.6 2797 - 457707 - - - 4.7323 - 3.595 0.442 - 193.6 1 2 0 0.0114 24 0 0 0 1.17E+07 9.08E+06 - - - 3.4807 0.9962 221125_WJC_METTL3_EV_vs_WT_F10.15283.15283.2 0.0282 16-Jun K.IGPLGLSPK.K sp|P30050|RL12_HUMAN 1 880.5382 12.87 145557 15283 2 880.53819 441.2764 60S ribosomal protein L12 OS=Homo sapiens OX=9606 GN=RPL12 PE=1 SV=1 8.75 2798.7 - 172654 - - - -0.0148 - 1.046 0.287 - 101 1 2 0 0 9 0 0 0 9.65E+06 7.50E+05 - - - 1.2909 0.9997 221125_WJC_METTL3_EV_vs_WT_F10.15287.15287.4 0.00577 18/108 R.SDK[136.11]PNASDPSVPLK[136.11]IPLQR[166.11].N "sp|Q9BQP7|MGME1_HUMAN,tr|Q5QPE7|Q5QPE7_HUMAN" 2 2087.1585 0.74 145559 15287 4 2087.157033 522.7969 Mitochondrial genome maintenance exonuclease 1 OS=Homo sapiens OX=9606 GN=MGME1 PE=1 SV=1 8.31 2799.3 - 345953 - - - -0.7144 - 3.099 0.432 - 216.5 1 2 1 -0.0015 19 0 0 0 7.63E+06 1.04E+07 - - - 3.3683 1 221125_WJC_METTL3_EV_vs_WT_F10.15291.15291.4 9.45E-09 21/144 K.WTHDKYQGDGIVEDEEETMENNEEK.K "sp|Q9NYF8|BCLF1_HUMAN,tr|H0YF63|H0YF63_HUMAN,tr|E9PK91|E9PK91_HUMAN,tr|H0YF14|H0YF14_HUMAN" 4 3024.2567 2.5 145560 15291 4 3024.261863 757.0715 Bcl-2-associated transcription factor 1 OS=Homo sapiens OX=9606 GN=BCLAF1 PE=1 SV=2 4 2799.9 - 592649 - - - 1.7055 - 4.229 0.666 - 332 1 2 1 0.0052 25 0 0 0 2.85E+08 1.14E+08 - - - 5.4802 0.9998 221125_WJC_METTL3_EV_vs_WT_F10.15296.15296.4 4.29E-08 15/108 R.SDKPNASDPSVPLKIPLQR.N "sp|Q9BQP7|MGME1_HUMAN,tr|Q5QPE7|Q5QPE7_HUMAN" 2 2061.1219 0.74 145563 15296 4 2061.123454 516.2877 Mitochondrial genome maintenance exonuclease 1 OS=Homo sapiens OX=9606 GN=MGME1 PE=1 SV=1 8.31 2800.5 - 213606 - - - 0.7763 - 3.047 0.447 - 159.8 1 2 1 0.0016 19 0 0 0 7.63E+06 1.04E+07 - - - 3.4931 1 221125_WJC_METTL3_EV_vs_WT_F10.15298.15298.4 1.23E-11 26/138 K.TAHNSEADLEESFNEHELEPSSPK[136.11].S sp|Q8IWS0|PHF6_HUMAN 1 2704.198 0.71 145564 15298 4 2704.196719 677.0568 PHD finger protein 6 OS=Homo sapiens OX=9606 GN=PHF6 PE=1 SV=1 4.3 2800.8 - 1.27E+06 - - - -0.473 - 4.758 0.651 - 488.8 1 2 0 -0.0013 24 0 0 0 2.85E+07 4.04E+07 - - - 5.3926 0.9999 221125_WJC_METTL3_EV_vs_WT_F10.15303.15303.3 0.000324 Jun-92 K.TAHNSEADLEESFNEHELEPSSPK.S sp|Q8IWS0|PHF6_HUMAN 1 2696.1838 0.44 145567 15303 3 2696.182211 899.7352 PHD finger protein 6 OS=Homo sapiens OX=9606 GN=PHF6 PE=1 SV=1 4.3 2801.4 - 268182 - - - -0.5886 - 1.635 0.463 - 29.3 1 2 0 -0.0016 24 0 0 0 3.32E+06 7.49E+06 - - - 4.8434 1 221125_WJC_METTL3_EV_vs_WT_F10.15306.15306.4 7.02E-10 27/144 K.WTHDK[136.11]YQGDGIVEDEEETMENNEEK[136.11].K "sp|Q9NYF8|BCLF1_HUMAN,tr|H0YF63|H0YF63_HUMAN,tr|E9PK91|E9PK91_HUMAN,tr|H0YF14|H0YF14_HUMAN" 4 3040.2851 2.49 145568 15306 4 3040.281082 761.0786 Bcl-2-associated transcription factor 1 OS=Homo sapiens OX=9606 GN=BCLAF1 PE=1 SV=2 4 2801.8 - 1.18E+06 - - - -1.3232 - 4.063 0.67 - 428.1 1 2 1 -0.004 25 0 0 0 2.84E+08 1.14E+08 - - - 5.5025 1 221125_WJC_METTL3_EV_vs_WT_F10.15312.15312.3 9.46E-14 21/96 K.WTHDKYQGDGIVEDEEETMENNEEK.K "sp|Q9NYF8|BCLF1_HUMAN,tr|H0YF63|H0YF63_HUMAN,tr|E9PK91|E9PK91_HUMAN,tr|H0YF14|H0YF14_HUMAN" 4 3024.2567 3.53 145569 15312 3 3024.255363 1009.0928 Bcl-2-associated transcription factor 1 OS=Homo sapiens OX=9606 GN=BCLAF1 PE=1 SV=2 4 2802.8 - 343634 - - - -0.4437 - 4.159 0.788 - 470.1 1 2 1 -0.0013 25 0 0 0 3.32E+07 9.39E+06 - - - 10.6041 1 221125_WJC_METTL3_EV_vs_WT_F10.15315.15315.3 4.66E-05 Dec-52 K.K[136.11]QELEEIC[160.03]HDLEAR[166.11].V sp|P35579|MYH9_HUMAN 1 1786.8639 0.64 145571 15315 3 1786.865053 596.6286 Myosin-9 OS=Homo sapiens OX=9606 GN=MYH9 PE=1 SV=4 4.57 2803.1 - 226797 - - - 0.6632 - 2.824 0.541 - 212.6 1 2 0 0.0012 14 0 0 0 3.65E+06 5.68E+06 - - - 7.3302 1 221125_WJC_METTL3_EV_vs_WT_F10.15326.15326.4 0.000264 9/108 R.SQLESHSDQNMHQAEEWFK.C "sp|P07197|NFM_HUMAN,tr|E7ESP9|E7ESP9_HUMAN,tr|E7EMV2|E7EMV2_HUMAN" 3 2330.0022 2.31 145577 15326 4 2330.001167 583.5078 Neurofilament medium polypeptide OS=Homo sapiens OX=9606 GN=NEFM PE=1 SV=3 4.8 2804.6 - 489684 - - - -0.4472 - 2.321 0.5 - 49.3 1 2 0 -0.001 19 0 0 0 1.08E+07 4.65E+06 - - - 3.8625 0.9987 221125_WJC_METTL3_EV_vs_WT_F10.15336.15336.4 0.000133 Nov-90 R.HDK[136.11]VEDALNLK[136.11]EEFDR[166.11].L "sp|P42704|LPPRC_HUMAN,tr|A0A804HI14|A0A804HI14_HUMAN,tr|A0A804HL40|A0A804HL40_HUMAN,tr|A0A804HKJ0|A0A804HKJ0_HUMAN,tr|A0A804HKR3|A0A804HKR3_HUMAN,tr|A0A804HIN4|A0A804HIN4_HUMAN,tr|A0A804HLG8|A0A804HLG8_HUMAN,tr|A0A804HHY9|A0A804HHY9_HUMAN,tr|A0A804HJH8|A0A804HJH8_HUMAN,tr|B8ZZ38|B8ZZ38_HUMAN,tr|A0A804HI40|A0A804HI40_HUMAN,tr|A0A804HJZ1|A0A804HJZ1_HUMAN,tr|C9JCA9|C9JCA9_HUMAN,tr|A0A804HIQ7|A0A804HIQ7_HUMAN,tr|A0A804HK30|A0A804HK30_HUMAN,tr|A0A804HKI2|A0A804HKI2_HUMAN,tr|A0A804HJI0|A0A804HJI0_HUMAN,tr|A0A804HIG4|A0A804HIG4_HUMAN,tr|A0A804HK02|A0A804HK02_HUMAN" 19 1982.9908 3.91 145583 15336 4 1982.9875 496.755 "Leucine-rich PPR motif-containing protein, mitochondrial OS=Homo sapiens OX=9606 GN=LRPPRC PE=1 SV=3" 4.58 2805.9 - 204817 - - - -1.6591 - 2.141 0.359 - 90.7 1 2 2 -0.0033 16 0 0 0 2.19E+07 5.59E+06 - - - 2.618 0.9322 221125_WJC_METTL3_EV_vs_WT_F10.15347.15347.3 0.53 May-36 R.LVNHFVEEFK[136.11].R "sp|P0DMV8|HS71A_HUMAN,sp|P0DMV9|HS71B_HUMAN,tr|V9GZ37|V9GZ37_HUMAN,tr|A0A0G2JIW1|A0A0G2JIW1_HUMAN" 4 1268.6645 0.07 145589 15347 3 1268.663678 423.8954 Heat shock 70 kDa protein 1A OS=Homo sapiens OX=9606 GN=HSPA1A PE=1 SV=1 5.4 2807.2 - 212636 - - - -0.6266 - 0.98 0.197 - 41.3 1 2 0 -0.0008 10 0 0 0 1.33E+06 1.83E+07 - - - 0.6771 0.9876 221125_WJC_METTL3_EV_vs_WT_F10.15350.15350.3 2.01E-07 18/92 R.TSFSPC[160.03]VPQC[160.03]QTQGSYGSFTEQHR.S sp|Q5T749|KPRP_HUMAN 1 2788.197 999 145590 15350 3 2789.217046 930.4063 Keratinocyte proline-rich protein OS=Homo sapiens OX=9606 GN=KPRP PE=1 SV=1 6.41 2807.6 - 852220 - - - 365.8576 - 3.196 0.607 - 148.2 1 2 0 1.0201 24 0 0 0 2.53E+08 0.00E+00 - - - 7.7235 1 221125_WJC_METTL3_EV_vs_WT_F10.15351.15351.4 0.000141 14/168 K.EGEEQPVLPEETESSK[136.11]PGPSAHDLAAQLK[136.11].S "sp|O95071|UBR5_HUMAN,tr|E7EMW7|E7EMW7_HUMAN" 2 3088.5172 0.54 145591 15351 4 3088.512815 773.1366 E3 ubiquitin-protein ligase UBR5 OS=Homo sapiens OX=9606 GN=UBR5 PE=1 SV=2 4.3 2807.7 - 560240 - - - -1.4049 - 2.823 0.506 - 63.5 1 2 0 -0.0043 29 0 0 0 7.42E+06 1.38E+07 - - - 3.9489 1 221125_WJC_METTL3_EV_vs_WT_F10.15352.15352.3 4.23E-07 20/108 R.VSGLQGSDALNIQQNQTSGGSLQAGQQK[136.11].E sp|P08047|SP1_HUMAN 1 2821.4046 0.98 145592 15352 3 2821.402075 941.4755 Transcription factor Sp1 OS=Homo sapiens OX=9606 GN=SP1 PE=1 SV=3 5.81 2807.9 - 716344 - - - -0.8868 - 3.906 0.643 - 374.2 1 2 0 -0.0025 28 0 0 0 4.03E+07 4.12E+07 - - - 8.8428 1 221125_WJC_METTL3_EV_vs_WT_F10.15360.15360.3 2.69E-14 22/108 R.VSGLQGSDALNIQQNQTSGGSLQAGQQK.E sp|P08047|SP1_HUMAN 1 2813.3904 0.98 145595 15360 3 2813.387291 938.8041 Transcription factor Sp1 OS=Homo sapiens OX=9606 GN=SP1 PE=1 SV=3 5.81 2808.9 - 1.18E+06 - - - -1.0969 - 4.637 0.694 - 541.5 1 2 0 -0.0031 28 0 0 0 4.03E+07 4.12E+07 - - - 9.8059 1 221125_WJC_METTL3_EV_vs_WT_F10.15375.15375.3 5.27E-07 Oct-96 K.QGSLINSLKPSGPTPASGQLSSGDK.A "sp|P35658|NU214_HUMAN,tr|A0A0A0MSW3|A0A0A0MSW3_HUMAN,tr|A0A494C1F2|A0A494C1F2_HUMAN,tr|A0A494C104|A0A494C104_HUMAN,tr|H0Y837|H0Y837_HUMAN" 5 2425.2449 8.22 145601 15375 3 2425.245009 809.4222 Nuclear pore complex protein Nup214 OS=Homo sapiens OX=9606 GN=NUP214 PE=1 SV=2 8.59 2811 - 281812 - - - 0.0524 - 2.352 0.534 - 75.5 1 2 0 0.0001 25 0 0 0 1.13E+07 1.37E+06 - - - 6.4612 1 221125_WJC_METTL3_EV_vs_WT_F10.15382.15382.4 1.02E-09 11/126 T.GVHEEATEEDIHDK[136.11]FAEYGEIK[136.11].N "sp|Q9Y5S9|RBM8A_HUMAN,tr|A0A0J9YW13|A0A0J9YW13_HUMAN" 2 2561.1893 8.17 145604 15382 4 2561.188708 641.3046 RNA-binding protein 8A OS=Homo sapiens OX=9606 GN=RBM8A PE=1 SV=1 4.37 2812 - 377025 - - - -0.2226 - 3.049 0.628 - 81.2 1 1 1 -0.0006 22 0 0 0 1.07E+08 1.31E+07 - - - 5.0567 0.9999 221125_WJC_METTL3_EV_vs_WT_F10.15399.15399.3 3.03E-05 Oct-56 R.GPSLNPVLDYDHGSR[166.11].S "sp|P43243|MATR3_HUMAN,tr|A8MXP9|A8MXP9_HUMAN,tr|D6R991|D6R991_HUMAN,tr|A0A0R4J2E8|A0A0R4J2E8_HUMAN,tr|D6REM6|D6REM6_HUMAN" 5 1635.7881 1.1 145611 15399 3 1635.784926 546.27 Matrin-3 OS=Homo sapiens OX=9606 GN=MATR3 PE=1 SV=2 5.21 2814.3 - 190118 - - - -1.9122 - 2.221 0.445 - 151.8 1 2 0 -0.0031 15 0 0 0 8.14E+06 7.37E+06 - - - 5.5826 0.9999 221125_WJC_METTL3_EV_vs_WT_F10.15402.15402.4 7.84E-07 26/168 K.TPSSDVLVFDYTK[136.11]HPSK[136.11]PDPSGEC[160.03]NPDLR[166.11].L sp|Q09028|RBBP4_HUMAN 1 3283.5666 0.4 145612 15402 4 3283.56938 821.8989 Histone-binding protein RBBP4 OS=Homo sapiens OX=9606 GN=RBBP4 PE=1 SV=3 4.75 2814.7 - 1.23E+06 - - - 0.8536 - 4.35 0.596 - 275.8 1 2 1 0.0028 29 0 0 0 1.88E+07 4.68E+07 - - - 4.8659 0.9999 221125_WJC_METTL3_EV_vs_WT_F10.15414.15414.3 1.31E-06 Dec-56 R.GPSLNPVLDYDHGSR.S "sp|P43243|MATR3_HUMAN,tr|A8MXP9|A8MXP9_HUMAN,tr|D6R991|D6R991_HUMAN,tr|A0A0R4J2E8|A0A0R4J2E8_HUMAN,tr|D6REM6|D6REM6_HUMAN" 5 1625.7798 1.14 145616 15414 3 1625.774357 542.9339 Matrin-3 OS=Homo sapiens OX=9606 GN=MATR3 PE=1 SV=2 5.21 2816.4 - 110641 - - - -3.3381 - 2.373 0.558 - 192.1 1 2 0 -0.0054 15 0 0 0 8.23E+06 7.21E+06 - - - 7.0145 0.9999 221125_WJC_METTL3_EV_vs_WT_F10.15424.15424.4 1.68E-08 19/120 K.TTQFSC[160.03]TLGEKFEETTADGRK.T "sp|Q01469|FABP5_HUMAN,tr|I6L8B7|I6L8B7_HUMAN" 2 2405.1169 113.65 145620 15424 4 2405.114789 602.2865 Fatty acid-binding protein 5 OS=Homo sapiens OX=9606 GN=FABP5 PE=1 SV=3 4.87 2817.6 - 866569 - - - -0.8798 - 3.948 0.558 - 348.1 1 2 1 -0.0021 21 0 0 0 4.17E+07 3.67E+05 - - - 4.5363 0.9197 221125_WJC_METTL3_EV_vs_WT_F10.15425.15425.4 3.42E-06 13/144 V.AAFASSLVSGLNSSASEPAK[136.11]EPAK[136.11]K[136.11].S "sp|Q86U44|MTA70_HUMAN,tr|F5H6D8|F5H6D8_HUMAN,tr|H0YFV6|H0YFV6_HUMAN,tr|B4DTN4|B4DTN4_HUMAN" 4 2470.313 0 145621 15425 4 2470.30442 618.5855 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 8.54 2817.8 - 321747 - - - -3.4603 - 2.652 0.485 - 69.6 1 1 1 -0.0085 25 0 0 0 1.19E+05 9.48E+07 - - - 3.7553 0.9919 221125_WJC_METTL3_EV_vs_WT_F10.15435.15435.3 1.92E-08 13/108 F.GEQKPTGTFSSGGGSVASQGFGFSSPNK.T "sp|P35658|NU214_HUMAN,tr|A0A494C0Y1|A0A494C0Y1_HUMAN,tr|A0A0A0MSW3|A0A0A0MSW3_HUMAN,tr|B7ZAV2|B7ZAV2_HUMAN,tr|A0A494C1F2|A0A494C1F2_HUMAN,tr|H0Y837|H0Y837_HUMAN" 6 2702.2572 2.88 145626 15435 3 2702.247906 901.7597 Nuclear pore complex protein Nup214 OS=Homo sapiens OX=9606 GN=NUP214 PE=1 SV=2 8.59 2819 - 602812 - - - -3.4534 - 2.648 0.606 - 133.5 1 1 0 -0.0093 28 0 0 0 6.99E+07 2.43E+07 - - - 7.5341 1 221125_WJC_METTL3_EV_vs_WT_F10.15439.15439.3 6.14E-11 20/108 R.ATAPVPTVGEGYGYGHESELSQASAAAR.N "sp|Q9BWF3|RBM4_HUMAN,tr|E9PB51|E9PB51_HUMAN" 2 2775.31 2.16 145628 15439 3 2775.312945 926.1106 RNA-binding protein 4 OS=Homo sapiens OX=9606 GN=RBM4 PE=1 SV=1 4.75 2819.6 - 472015 - - - 1.0608 - 3.786 0.687 - 254.9 1 2 0 0.0029 28 0 0 0 1.45E+07 6.73E+06 - - - 9.2614 1 221125_WJC_METTL3_EV_vs_WT_F10.15441.15441.4 4.71E-12 19/120 K.TSHSSTEAC[160.03]C[160.03]ELC[160.03]GLYFENRK.A "sp|O95785|WIZ_HUMAN,tr|A0A669KBG4|A0A669KBG4_HUMAN,tr|A0A2R8YFV2|A0A2R8YFV2_HUMAN,tr|A0A669KAV7|A0A669KAV7_HUMAN,tr|M0QXA7|M0QXA7_HUMAN,tr|A0A669KBH9|A0A669KBH9_HUMAN,tr|B9EGQ5|B9EGQ5_HUMAN" 7 2548.0781 1.02 145629 15441 4 2548.077822 638.0268 Protein Wiz OS=Homo sapiens OX=9606 GN=WIZ PE=1 SV=2 5.46 2819.8 - 426697 - - - -0.1064 - 3.498 0.687 - 328.1 1 2 0 -0.0003 21 0 0 0 7.21E+06 7.07E+06 - - - 5.6196 1 221125_WJC_METTL3_EV_vs_WT_F10.15456.15456.3 5.52E-12 19/108 F.GEQK[136.11]PTGTFSSGGGSVASQGFGFSSPNK[136.11].T "sp|P35658|NU214_HUMAN,tr|A0A494C0Y1|A0A494C0Y1_HUMAN,tr|A0A0A0MSW3|A0A0A0MSW3_HUMAN,tr|B7ZAV2|B7ZAV2_HUMAN,tr|A0A494C1F2|A0A494C1F2_HUMAN,tr|H0Y837|H0Y837_HUMAN" 6 2718.2856 2.88 145635 15456 3 2718.286984 907.1025 Nuclear pore complex protein Nup214 OS=Homo sapiens OX=9606 GN=NUP214 PE=1 SV=2 8.59 2821.7 - 599738 - - - 0.4952 - 3.961 0.617 - 321.8 1 1 0 0.0013 28 0 0 0 6.99E+07 2.43E+07 - - - 8.5854 1 221125_WJC_METTL3_EV_vs_WT_F10.15466.15466.3 1.53E-13 26/132 R.SDSPVPTAPTSGGPK[136.11]PSTASAVPELATDPELEK[136.11]K[136.11].L "sp|Q86U44|MTA70_HUMAN,tr|B4E349|B4E349_HUMAN,tr|F5H6D8|F5H6D8_HUMAN,tr|B4DTN4|B4DTN4_HUMAN" 4 3384.7363 -1 145638 15466 3 3384.728282 1129.2527 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 4.51 2823.1 - 1.52E+06 - - - -2.3573 - 3.756 0.685 - 342.9 1 2 0 -0.008 34 0 0 0 0.00E+00 0.00E+00 - - - 9.2194 0.9591 221125_WJC_METTL3_EV_vs_WT_F10.15483.15483.3 0.00429 Oct-44 K.NKLEGLEDALQK.A "sp|P48668|K2C6C_HUMAN,sp|P04259|K2C6B_HUMAN,sp|P02538|K2C6A_HUMAN" 3 1356.7249 999 145644 15483 3 1356.721969 453.2489 "Keratin, type II cytoskeletal 6C OS=Homo sapiens OX=9606 GN=KRT6C PE=1 SV=3" 4.68 2825.3 - 639253 - - - -2.1567 - 1.986 0.166 - 202.4 1 2 1 -0.0029 12 0 0 0 1.36E+07 0.00E+00 - - - 2.2918 1 221125_WJC_METTL3_EV_vs_WT_F10.15519.15519.4 4.23E-09 26/132 R.GGDVFGDTSFLSNHGGSSGSTHR.S sp|Q00587|BORG5_HUMAN 1 2277.9999 2.13 145647 15519 4 2277.993746 570.5073 Cdc42 effector protein 1 OS=Homo sapiens OX=9606 GN=CDC42EP1 PE=1 SV=1 5.98 2831.1 - 5.11E+06 - - - -2.7019 - 3.885 0.612 - 500.5 1 2 0 -0.0062 23 0 0 0 9.65E+07 4.53E+07 - - - 4.9908 1 221125_WJC_METTL3_EV_vs_WT_F10.15549.15549.2 1.10E-05 17/22 V.PELATDPELEK[136.11]K[136.11].L "sp|Q86U44|MTA70_HUMAN,tr|B4E349|B4E349_HUMAN,tr|F5H6D8|F5H6D8_HUMAN,tr|H0YFV6|H0YFV6_HUMAN,tr|B4DTN4|B4DTN4_HUMAN" 5 1384.7421 0.01 145648 15549 2 1384.736178 693.3783 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 4.41 2836.2 - 6.77E+06 - - - -4.2484 - 3.324 0.503 - 971.2 1 1 0 -0.0059 12 0 0 0 5.70E+06 1.00E+09 - - - 5.9148 1 221125_WJC_METTL3_EV_vs_WT_F10.15609.15609.2 6.65E-05 26/66 R.SDSPVPTAPTSGGPK[136.11]PSTASAVPELATDPELEK[136.11]K[136.11].L "sp|Q86U44|MTA70_HUMAN,tr|B4E349|B4E349_HUMAN,tr|F5H6D8|F5H6D8_HUMAN,tr|B4DTN4|B4DTN4_HUMAN" 4 3384.7363 0.001 145649 15609 2 3386.73206 1693.3754 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 4.51 2846.5 - 1.34E+07 - - - 589.6468 - 3.791 0.608 - 508.7 1 2 0 1.9958 34 0 0 0 0.00E+00 7.56E+08 - - - 6.1813 0.9904 221125_WJC_METTL3_EV_vs_WT_F10.15636.15636.3 0.000549 20/44 V.PELATDPELEK[136.11]K[136.11].L "sp|Q86U44|MTA70_HUMAN,tr|B4E349|B4E349_HUMAN,tr|F5H6D8|F5H6D8_HUMAN,tr|H0YFV6|H0YFV6_HUMAN,tr|B4DTN4|B4DTN4_HUMAN" 5 1384.7421 0.001 145651 15636 3 1384.737076 462.588 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 4.41 2851 - 1.23E+06 - - - -3.5999 - 3.333 0.497 - 590.4 1 1 0 -0.005 12 0 0 0 0.00E+00 2.42E+08 - - - 7.4166 0.9992 221125_WJC_METTL3_EV_vs_WT_F10.15695.15695.3 1.02E-06 18/40 K.FAAQELIEVK[136.11]R[166.11].G "sp|Q86U44|MTA70_HUMAN,tr|F5H6D8|F5H6D8_HUMAN,tr|H0YFV6|H0YFV6_HUMAN,tr|B4DTN4|B4DTN4_HUMAN" 4 1320.7521 0.001 145653 15695 3 1320.747909 441.258 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 6.14 2861 - 1.24E+06 - - - -3.1399 - 2.606 0.298 - 342.5 1 2 0 -0.0041 11 0 0 0 0.00E+00 5.01E+07 - - - 4.5823 1 221125_WJC_METTL3_EV_vs_WT_F10.15699.15699.4 3.56E-07 25/120 R.DDSFFGETSHNYHKFDSEYER.M "sp|P43243|MATR3_HUMAN,tr|A8MXP9|A8MXP9_HUMAN,tr|D6R991|D6R991_HUMAN,tr|A0A0R4J2E8|A0A0R4J2E8_HUMAN,tr|H0Y8T4|H0Y8T4_HUMAN,tr|D6REM6|D6REM6_HUMAN" 6 2609.0731 1.41 145654 15699 4 2609.067218 653.2756 Matrin-3 OS=Homo sapiens OX=9606 GN=MATR3 PE=1 SV=2 4.57 2861.5 - 1.64E+06 - - - -2.264 - 4.603 0.615 - 580.3 1 2 1 -0.0059 21 0 0 0 6.56E+07 4.64E+07 - - - 5.0821 1 221125_WJC_METTL3_EV_vs_WT_F10.15711.15711.4 2.28E-08 24/138 K.KQSKPVTTPEEIAQVATISANGDK.E "sp|P10809|CH60_HUMAN,tr|A0A7I2V599|A0A7I2V599_HUMAN,tr|E7EXB4|E7EXB4_HUMAN,tr|A0A7I2YQ71|A0A7I2YQ71_HUMAN,tr|E7ESH4|E7ESH4_HUMAN,tr|A0A7I2V5M1|A0A7I2V5M1_HUMAN,tr|A0A7I2V5K3|A0A7I2V5K3_HUMAN,tr|A0A7I2V369|A0A7I2V369_HUMAN" 8 2511.318 1.4 145659 15711 4 2511.316994 628.8368 "60 kDa heat shock protein, mitochondrial OS=Homo sapiens OX=9606 GN=HSPD1 PE=1 SV=2" 6.18 2863 - 1.90E+06 - - - -0.4193 - 4.242 0.585 - 383.1 1 2 0 -0.0011 24 0 0 0 1.48E+08 1.05E+08 - - - 4.7814 1 221125_WJC_METTL3_EV_vs_WT_F10.15714.15714.3 4.42E-12 31/132 R.SDSPVPTAPTSGGPK[136.11]PSTASAVPELATDPELEK[136.11]K[136.11].L "sp|Q86U44|MTA70_HUMAN,tr|B4E349|B4E349_HUMAN,tr|F5H6D8|F5H6D8_HUMAN,tr|B4DTN4|B4DTN4_HUMAN" 4 3384.7363 0 145660 15714 3 3384.726829 1129.2527 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 4.51 2863.4 - 2.05E+07 - - - -2.7866 - 4.465 0.67 - 512 1 2 0 -0.0094 34 0 0 0 3.74E+07 2.91E+10 - - - 9.4496 1 221125_WJC_METTL3_EV_vs_WT_F10.15716.15716.4 2.32E-09 20/138 K.K[136.11]QSK[136.11]PVTTPEEIAQVATISANGDK[136.11].E "sp|P10809|CH60_HUMAN,tr|A0A7I2V599|A0A7I2V599_HUMAN,tr|E7EXB4|E7EXB4_HUMAN,tr|A0A7I2YQ71|A0A7I2YQ71_HUMAN,tr|E7ESH4|E7ESH4_HUMAN,tr|A0A7I2V5M1|A0A7I2V5M1_HUMAN,tr|A0A7I2V5K3|A0A7I2V5K3_HUMAN,tr|A0A7I2V369|A0A7I2V369_HUMAN" 8 2535.3606 1.41 145661 15716 4 2535.35954 634.8474 "60 kDa heat shock protein, mitochondrial OS=Homo sapiens OX=9606 GN=HSPD1 PE=1 SV=2" 6.18 2863.6 - 1.96E+06 - - - -0.4366 - 3.548 0.51 - 268.9 1 2 0 -0.0011 24 0 0 0 1.49E+08 1.06E+08 - - - 4.0712 0.9999 221125_WJC_METTL3_EV_vs_WT_F10.15722.15722.4 9.46E-13 28/120 R.DDSFFGETSHNYHK[136.11]FDSEYER[166.11].M "sp|P43243|MATR3_HUMAN,tr|A8MXP9|A8MXP9_HUMAN,tr|D6R991|D6R991_HUMAN,tr|A0A0R4J2E8|A0A0R4J2E8_HUMAN,tr|H0Y8T4|H0Y8T4_HUMAN,tr|D6REM6|D6REM6_HUMAN" 6 2627.0956 1.41 145664 15722 4 2627.091205 657.7812 Matrin-3 OS=Homo sapiens OX=9606 GN=MATR3 PE=1 SV=2 4.57 2864.3 - 1.26E+06 - - - -1.671 - 4.876 0.607 - 848 1 2 1 -0.0044 21 0 0 0 6.56E+07 4.64E+07 - - - 5.032 0.9999 221125_WJC_METTL3_EV_vs_WT_F10.15751.15751.4 2.02E-08 21/120 R.K[136.11]QDSGHLDLR[166.11]NPEAALSPTFR[166.11].S "sp|Q86U44|MTA70_HUMAN,tr|B4E349|B4E349_HUMAN,tr|F5H6D8|F5H6D8_HUMAN,tr|B4DTN4|B4DTN4_HUMAN" 4 2379.2289 0 145674 15751 4 2379.231809 595.8145 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 6.76 2868.2 - 586444 - - - 1.2033 - 3.826 0.546 - 326.6 1 2 1 0.0029 21 0 0 0 6.96E+04 1.38E+08 - - - 4.4212 1 221125_WJC_METTL3_EV_vs_WT_F10.15755.15755.3 2.97E-08 21/52 K.HWPFQVINDGDK[136.11]PK[136.11].V "sp|P0DMV8|HS71A_HUMAN,sp|P0DMV9|HS71B_HUMAN,tr|A0A0G2JIW1|A0A0G2JIW1_HUMAN" 3 1695.8704 0.11 145675 15755 3 1695.868077 566.2974 Heat shock 70 kDa protein 1A OS=Homo sapiens OX=9606 GN=HSPA1A PE=1 SV=1 6.75 2868.8 - 1.12E+06 - - - -1.3639 - 3.328 0.587 - 867.6 1 2 0 -0.0023 14 0 0 0 2.95E+07 2.69E+08 - - - 8.2792 1 221125_WJC_METTL3_EV_vs_WT_F10.15756.15756.4 7.39E-06 15/78 K.HWPFQVINDGDK[136.11]PK[136.11].V "sp|P0DMV8|HS71A_HUMAN,sp|P0DMV9|HS71B_HUMAN,tr|A0A0G2JIW1|A0A0G2JIW1_HUMAN" 3 1695.8704 0.12 145676 15756 4 1695.868779 424.9749 Heat shock 70 kDa protein 1A OS=Homo sapiens OX=9606 GN=HSPA1A PE=1 SV=1 6.75 2868.9 - 335924 - - - -0.95 - 2.414 0.581 - 156.6 1 2 0 -0.0016 14 0 0 0 7.11E+06 5.88E+07 - - - 4.6033 0.9999 221125_WJC_METTL3_EV_vs_WT_F10.15798.15798.3 1.69E-06 Nov-52 K.HWPFQVINDGDKPK.V "sp|P0DMV8|HS71A_HUMAN,sp|P0DMV9|HS71B_HUMAN,tr|A0A0G2JIW1|A0A0G2JIW1_HUMAN" 3 1679.842 0.11 145695 15798 3 1679.847077 560.9546 Heat shock 70 kDa protein 1A OS=Homo sapiens OX=9606 GN=HSPA1A PE=1 SV=1 6.75 2874.5 - 155295 - - - 3.0283 - 2.263 0.513 - 195.6 1 2 0 0.0051 14 0 0 0 2.99E+07 2.80E+08 - - - 6.4284 0.9914 221125_WJC_METTL3_EV_vs_WT_F10.15837.15837.3 0.0525 Jul-68 K.FAASGGFLHHMAGLSSSK.L "sp|Q9BY77|PDIP3_HUMAN,tr|F6VRR5|F6VRR5_HUMAN,tr|F8WCX5|F8WCX5_HUMAN,tr|Q8WUT1|Q8WUT1_HUMAN" 4 1803.8726 4.76 145713 15837 3 1803.875662 602.2982 Polymerase delta-interacting protein 3 OS=Homo sapiens OX=9606 GN=POLDIP3 PE=1 SV=2 8.76 2879.8 - 120793 - - - 1.6764 - 1.375 0.256 - 45.6 1 2 0 0.003 18 0 0 0 1.17E+07 2.47E+06 - - - 2.1863 0.9999 221125_WJC_METTL3_EV_vs_WT_F10.15843.15843.3 2.51E-08 Nov-80 R.K[136.11]QDSGHLDLR[166.11]NPEAALSPTFR[166.11].S "sp|Q86U44|MTA70_HUMAN,tr|B4E349|B4E349_HUMAN,tr|F5H6D8|F5H6D8_HUMAN,tr|B4DTN4|B4DTN4_HUMAN" 4 2379.2289 0.02 145715 15843 3 2379.231767 794.0836 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 6.76 2880.6 - 241950 - - - 1.1857 - 2.659 0.541 - 96.3 1 2 1 0.0028 21 0 0 0 1.39E+05 6.44E+06 - - - 6.9154 0.9999 221125_WJC_METTL3_EV_vs_WT_F10.15845.15845.3 3.81E-09 13/100 K.SEPVKEESSELEQPFAQDTSSVGPDR.K "sp|Q14151|SAFB2_HUMAN,sp|Q15424|SAFB1_HUMAN" 2 2847.3046 2.03 145716 15845 3 2847.30373 950.1088 Scaffold attachment factor B2 OS=Homo sapiens OX=9606 GN=SAFB2 PE=1 SV=1 4 2880.9 - 197029 - - - -0.32 - 2.958 0.612 - 119 1 2 1 -0.0009 26 0 0 0 2.09E+07 1.03E+07 - - - 7.858 0.9998 221125_WJC_METTL3_EV_vs_WT_F10.15862.15862.4 0.000944 8/102 R.K[136.11]TSDANETEDHLESLIC[160.03]K[136.11].V "sp|Q09161|NCBP1_HUMAN,tr|F2Z2T1|F2Z2T1_HUMAN" 2 2104.9918 1.44 145723 15862 4 2104.996238 527.2552 Nuclear cap-binding protein subunit 1 OS=Homo sapiens OX=9606 GN=NCBP1 PE=1 SV=1 4.5 2883.3 - 114577 - - - 2.1254 - 1.933 0.438 - 42.7 1 2 0 0.0045 18 0 0 0 1.19E+07 8.21E+06 - - - 3.2629 0.9992 221125_WJC_METTL3_EV_vs_WT_F10.15867.15867.4 0.000428 12/102 R.KTSDANETEDHLESLIC[160.03]K.V "sp|Q09161|NCBP1_HUMAN,tr|F2Z2T1|F2Z2T1_HUMAN" 2 2088.9634 1.44 145726 15867 4 2088.966411 523.2481 Nuclear cap-binding protein subunit 1 OS=Homo sapiens OX=9606 GN=NCBP1 PE=1 SV=1 4.5 2884 - 186790 - - - 1.4586 - 2.134 0.314 - 104.7 1 2 0 0.003 18 0 0 0 1.19E+07 8.21E+06 - - - 2.2179 1 221125_WJC_METTL3_EV_vs_WT_F10.15873.15873.3 1.33E-11 16/100 K.SEPVK[136.11]EESSELEQPFAQDTSSVGPDR[166.11].K "sp|Q14151|SAFB2_HUMAN,sp|Q15424|SAFB1_HUMAN" 2 2865.3271 2.03 145728 15873 3 2865.336108 956.1163 Scaffold attachment factor B2 OS=Homo sapiens OX=9606 GN=SAFB2 PE=1 SV=1 4 2884.9 - 224678 - - - 3.14 - 3.557 0.686 - 204.5 1 2 1 0.009 26 0 0 0 2.09E+07 1.03E+07 - - - 9.105 0.9799 221125_WJC_METTL3_EV_vs_WT_F10.15881.15881.2 0.306 16-Aug K.TLLDIDNTR.M sp|P35527|K1C9_HUMAN 1 1059.556 999 145729 15881 2 1059.560024 530.7853 "Keratin, type I cytoskeletal 9 OS=Homo sapiens OX=9606 GN=KRT9 PE=1 SV=3" 4.21 2886.2 - 192228 - - - 3.762 - 1.466 0.197 - 228.6 1 2 0 0.004 9 0 0 0 1.54E+07 0.00E+00 - - - 1.6015 0.9998 221125_WJC_METTL3_EV_vs_WT_F10.15883.15883.4 1.37E-06 11/162 K.ITSSSAIYDNPNLIKPIPVKPSENQQQR.L "sp|Q8IZD4|DCP1B_HUMAN,tr|F5GZK9|F5GZK9_HUMAN" 2 3136.6517 1.3 145730 15883 4 3136.666297 785.1702 mRNA-decapping enzyme 1B OS=Homo sapiens OX=9606 GN=DCP1B PE=1 SV=2 8.5 2886.4 - 191797 - - - 4.661 - 2.769 0.571 - 51.2 1 2 0 0.0146 28 0 0 0 6.44E+06 4.96E+06 - - - 4.5082 0.9518 221125_WJC_METTL3_EV_vs_WT_F10.15885.15885.4 0.65 7/156 R.NTTPLPRPPPGLTNPKPSSPWSSTAPR.S "sp|Q9UPQ9|TNR6B_HUMAN,tr|H0Y720|H0Y720_HUMAN" 2 2852.4933 5.19 145731 15885 4 2852.492187 714.1306 Trinucleotide repeat-containing gene 6B protein OS=Homo sapiens OX=9606 GN=TNRC6B PE=1 SV=4 12.01 2886.6 - 173334 - - - -0.3993 - 1.418 0.149 - 18.7 1 2 0 -0.0011 27 0 0 0 9.85E+06 1.90E+06 - - - 0.6319 0.9999 221125_WJC_METTL3_EV_vs_WT_F10.15926.15926.3 6.39E-09 19/76 K.R[166.11]GLLQDDAHPTLVTYADHSK[136.11].L "sp|Q86U44|MTA70_HUMAN,tr|F5H6D8|F5H6D8_HUMAN,tr|H0YFV6|H0YFV6_HUMAN,tr|B4DTN4|B4DTN4_HUMAN" 4 2254.1461 11.75 145744 15926 3 2254.154838 752.3893 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 5.99 2892.5 - 353213 - - - 3.8698 - 3.707 0.576 - 474 1 2 0 0.0087 20 0 0 0 5.48E+07 4.67E+06 - - - 8.138 0.995 221125_WJC_METTL3_EV_vs_WT_F10.15927.15927.3 0.000202 Aug-52 K.LGKDAVEDLESVGK.G sp|P81605|DCD_HUMAN 1 1458.7566 999 145745 15927 3 1458.756603 487.2595 Dermcidin OS=Homo sapiens OX=9606 GN=DCD PE=1 SV=2 4.32 2892.6 - 179629 - - - 0.0096 - 1.775 0.286 - 104.7 1 2 1 0 14 0 0 0 6.52E+06 0.00E+00 - - - 3.2535 1 221125_WJC_METTL3_EV_vs_WT_F10.15933.15933.3 1.93E-10 24/124 R.TPGAATASASGAAEDGAC[160.03]GC[160.03]LPNPGTFEEC[160.03]HR.K "sp|O96008|TOM40_HUMAN,tr|K7EJ57|K7EJ57_HUMAN" 2 3218.3452 2.04 145748 15933 3 3218.346314 1073.789 Mitochondrial import receptor subunit TOM40 homolog OS=Homo sapiens OX=9606 GN=TOMM40 PE=1 SV=1 4.4 2893.4 - 326585 - - - 0.3586 - 3.991 0.774 - 272.3 1 2 0 0.0012 32 0 0 0 2.55E+07 1.25E+07 - - - 10.3532 0.9997 221125_WJC_METTL3_EV_vs_WT_F10.15952.15952.4 0.0346 8/120 K.ETTYYDVLGVK[136.11]PNATQEELK[136.11]K[136.11].A sp|P31689|DNJA1_HUMAN 1 2449.2803 0.7 145758 15952 4 2449.277738 613.3273 DnaJ homolog subfamily A member 1 OS=Homo sapiens OX=9606 GN=DNAJA1 PE=1 SV=2 4.87 2896 - 276137 - - - -1.0342 - 1.787 0.36 - 36.7 1 2 0 -0.0025 21 0 0 0 3.99E+06 5.71E+06 - - - 2.5507 1 221125_WJC_METTL3_EV_vs_WT_F10.15965.15965.4 1.06E-10 21/114 K.R[166.11]GLLQDDAHPTLVTYADHSK[136.11].L "sp|Q86U44|MTA70_HUMAN,tr|F5H6D8|F5H6D8_HUMAN,tr|H0YFV6|H0YFV6_HUMAN,tr|B4DTN4|B4DTN4_HUMAN" 4 2254.1461 0.01 145762 15965 4 2254.145492 564.5438 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 5.99 2897.7 - 1.61E+06 - - - -0.2764 - 3.864 0.608 - 447.6 1 2 0 -0.0006 20 0 0 0 8.04E+05 8.85E+07 - - - 4.9698 1 221125_WJC_METTL3_EV_vs_WT_F10.15974.15974.3 4.09E-07 16/52 K.HWPFQVINDGDK[136.11]PK[136.11].V "sp|P0DMV8|HS71A_HUMAN,sp|P0DMV9|HS71B_HUMAN,tr|A0A0G2JIW1|A0A0G2JIW1_HUMAN" 3 1695.8704 0.11 145766 15974 3 1695.869261 566.2974 Heat shock 70 kDa protein 1A OS=Homo sapiens OX=9606 GN=HSPA1A PE=1 SV=1 6.75 2898.9 - 516331 - - - -0.6657 - 3.102 0.509 - 483.2 1 2 0 -0.0011 14 0 0 0 2.95E+07 2.69E+08 - - - 7.223 0.9999 221125_WJC_METTL3_EV_vs_WT_F10.15978.15978.4 1.08E-06 12/126 K.KTATQTGHTLLEDYQIVDNSQR.E sp|Q8N0X7|SPART_HUMAN 1 2517.2459 0.96 145767 15978 4 2517.251239 630.3188 Spartin OS=Homo sapiens OX=9606 GN=SPART PE=1 SV=1 5.38 2899.4 - 234773 - - - 2.1031 - 2.61 0.491 - 105.5 1 2 0 0.0053 22 0 0 0 5.26E+07 5.50E+07 - - - 3.8121 0.9738 221125_WJC_METTL3_EV_vs_WT_F10.15983.15983.4 0.00707 7/174 K.QPTEEEASSK[136.11]EDSAPSK[136.11]PVVGIIYPPPEVR[166.11].N "sp|Q15459|SF3A1_HUMAN,tr|F8WB66|F8WB66_HUMAN" 2 3261.6615 -1 145769 15983 4 3261.672049 816.4227 Splicing factor 3A subunit 1 OS=Homo sapiens OX=9606 GN=SF3A1 PE=1 SV=1 4.42 2900.1 - 157207 - - - 3.2272 - 1.687 0.278 - 19.1 1 2 1 0.0105 30 0 0 0 0.00E+00 0.00E+00 - - - 1.8028 1 221125_WJC_METTL3_EV_vs_WT_F10.16001.16001.4 2.63E-07 19/204 K.LPSNSLGFTATHNTSPAAPPTEVTIC[160.03]QSSEVSKPK.L sp|Q5VT52|RPRD2_HUMAN 1 3652.8043 3.11 145777 16001 4 3652.803628 914.2083 Regulation of nuclear pre-mRNA domain-containing protein 2 OS=Homo sapiens OX=9606 GN=RPRD2 PE=1 SV=1 6.75 2902.5 - 680297 - - - -0.1815 - 3.229 0.567 - 103.7 1 2 0 -0.0007 35 0 0 0 7.27E+06 2.34E+06 - - - 4.5085 1 221125_WJC_METTL3_EV_vs_WT_F10.16016.16016.4 6.77E-08 17/192 R.ITPEPAVSNTEEPSTTSTASNYPDVLTRPSLHR.S sp|P49790|NU153_HUMAN 1 3566.7489 1.97 145782 16016 4 3566.754224 892.6945 Nuclear pore complex protein Nup153 OS=Homo sapiens OX=9606 GN=NUP153 PE=1 SV=2 4.83 2904.5 - 1.06E+06 - - - 1.4969 - 3.558 0.535 - 129 1 2 0 0.0053 33 0 0 0 4.40E+07 2.23E+07 - - - 4.262 0.9593 221125_WJC_METTL3_EV_vs_WT_F10.16022.16022.3 0.11 Jun-36 R.MVNHFIAEFK[136.11].R "sp|P11142|HSP7C_HUMAN,tr|A8K7Q2|A8K7Q2_HUMAN,tr|E9PKE3|E9PKE3_HUMAN,tr|E9PN89|E9PN89_HUMAN" 4 1242.6311 0.09 145785 16022 3 1242.629708 415.2176 Heat shock cognate 71 kDa protein OS=Homo sapiens OX=9606 GN=HSPA8 PE=1 SV=1 6.5 2905.4 - 200940 - - - -1.092 - 1.275 0.157 - 61.6 1 2 0 -0.0014 10 0 0 0 6.40E+05 6.91E+06 - - - 0.9995 1 221125_WJC_METTL3_EV_vs_WT_F10.16031.16031.4 2.16E-11 17/132 K.EKDSPHMQDPNQADEEAMTQIIR.V sp|P23511|NFYA_HUMAN 1 2682.2014 0.57 145790 16031 4 2682.203302 671.5576 Nuclear transcription factor Y subunit alpha OS=Homo sapiens OX=9606 GN=NFYA PE=1 SV=2 4.29 2906.5 - 548733 - - - 0.7169 - 3.661 0.665 - 185.3 1 2 1 0.0019 23 0 0 0 6.01E+06 1.05E+07 - - - 5.4341 0.9994 221125_WJC_METTL3_EV_vs_WT_F10.16033.16033.2 3.73E-05 24-Sep R.TTPSYVAFTDTER[166.11].L "sp|P48741|HSP77_HUMAN,sp|P54652|HSP72_HUMAN,sp|P0DMV8|HS71A_HUMAN,sp|P34931|HS71L_HUMAN,sp|P11142|HSP7C_HUMAN,sp|P0DMV9|HS71B_HUMAN,sp|P17066|HSP76_HUMAN,tr|E9PQQ4|E9PQQ4_HUMAN,tr|E9PNE6|E9PNE6_HUMAN,tr|E9PKE3|E9PKE3_HUMAN,tr|E9PLF4|E9PLF4_HUMAN,tr|Q53FA3|Q53FA3_HUMAN,tr|E9PI65|E9PI65_HUMAN,tr|E9PK54|E9PK54_HUMAN,tr|E9PN25|E9PN25_HUMAN,tr|E9PPY6|E9PPY6_HUMAN,tr|E9PQK7|E9PQK7_HUMAN,tr|A0A0G2JIW1|A0A0G2JIW1_HUMAN" 18 1496.7023 0.09 145792 16033 2 1496.697953 749.3584 Putative heat shock 70 kDa protein 7 OS=Homo sapiens OX=9606 GN=HSPA7 PE=5 SV=2 4.37 2906.8 - 241846 - - - -2.877 - 2.082 0.499 - 273 1 2 0 -0.0043 13 0 0 0 2.42E+06 2.59E+07 - - - 4.6074 1 221125_WJC_METTL3_EV_vs_WT_F10.16037.16037.4 9.87E-10 22/192 R.ITPEPAVSNTEEPSTTSTASNYPDVLTR[166.11]PSLHR[166.11].S sp|P49790|NU153_HUMAN 1 3586.7654 1.97 145793 16037 4 3586.774291 897.6986 Nuclear pore complex protein Nup153 OS=Homo sapiens OX=9606 GN=NUP153 PE=1 SV=2 4.83 2907.4 - 956529 - - - 2.4719 - 3.912 0.569 - 227.3 1 2 0 0.0089 33 0 0 0 4.40E+07 2.23E+07 - - - 4.5854 0.9999 221125_WJC_METTL3_EV_vs_WT_F10.16041.16041.4 3.56E-09 17/144 K.ESSSVLSC[160.03]DISADDKYIVTGSGDKK.A "sp|Q04726|TLE3_HUMAN,tr|A0A0D9SES8|A0A0D9SES8_HUMAN,tr|H0YL70|H0YL70_HUMAN,tr|H0YKN8|H0YKN8_HUMAN,tr|H0YKT5|H0YKT5_HUMAN,tr|H0YNI7|H0YNI7_HUMAN,tr|H0YNT2|H0YNT2_HUMAN" 7 2660.2487 1.35 145795 16041 4 2660.24649 666.0695 Transducin-like enhancer protein 3 OS=Homo sapiens OX=9606 GN=TLE3 PE=1 SV=2 4.36 2907.9 - 890040 - - - -0.8334 - 3.098 0.543 - 152.7 1 2 1 -0.0022 25 0 0 0 2.27E+07 1.68E+07 - - - 4.3114 0.9999 221125_WJC_METTL3_EV_vs_WT_F10.16043.16043.3 7.62E-05 Oct-52 K.SFFDNISC[160.03]DDNR[166.11]ER[166.11].R "sp|Q8ND56|LS14A_HUMAN,tr|A0A096LP11|A0A096LP11_HUMAN,tr|A0A140TA76|A0A140TA76_HUMAN,tr|A0A0G2JQ95|A0A0G2JQ95_HUMAN" 4 1793.7542 1.1 145796 16043 3 1793.753065 598.9253 Protein LSM14 homolog A OS=Homo sapiens OX=9606 GN=LSM14A PE=1 SV=3 4.23 2908.1 - 256362 - - - -0.6333 - 2.07 0.598 - 107.9 1 2 1 -0.0011 14 0 0 0 2.16E+07 1.97E+07 - - - 7.1403 0.9994 221125_WJC_METTL3_EV_vs_WT_F10.16045.16045.4 0.00462 8/174 K.QPTEEEASSKEDSAPSKPVVGIIYPPPEVR.N "sp|Q15459|SF3A1_HUMAN,tr|F8WB66|F8WB66_HUMAN" 2 3235.6249 0.68 145798 16045 4 3235.627004 809.9135 Splicing factor 3A subunit 1 OS=Homo sapiens OX=9606 GN=SF3A1 PE=1 SV=1 4.42 2908.3 - 389458 - - - 0.6648 - 1.964 0.409 - 23.2 1 2 1 0.0022 30 0 0 0 1.22E+07 1.80E+07 - - - 2.9919 1 221125_WJC_METTL3_EV_vs_WT_F10.16058.16058.4 1.83E-14 21/144 K.ESSSVLSC[160.03]DISADDK[136.11]YIVTGSGDK[136.11]K[136.11].A "sp|Q04726|TLE3_HUMAN,tr|A0A0D9SES8|A0A0D9SES8_HUMAN,tr|H0YL70|H0YL70_HUMAN,tr|H0YKN8|H0YKN8_HUMAN,tr|H0YKT5|H0YKT5_HUMAN,tr|H0YNI7|H0YNI7_HUMAN,tr|H0YNT2|H0YNT2_HUMAN" 7 2684.2913 1.35 145804 16058 4 2684.294069 672.0801 Transducin-like enhancer protein 3 OS=Homo sapiens OX=9606 GN=TLE3 PE=1 SV=2 4.36 2910.1 - 780162 - - - 1.0289 - 3.581 0.69 - 334.2 1 2 1 0.0028 25 0 0 0 2.27E+07 1.68E+07 - - - 5.6368 0.9999 221125_WJC_METTL3_EV_vs_WT_F10.16073.16073.3 5.91E-05 14/52 K.SFFDNISC[160.03]DDNRER.R "sp|Q8ND56|LS14A_HUMAN,tr|A0A096LP11|A0A096LP11_HUMAN,tr|A0A140TA76|A0A140TA76_HUMAN,tr|A0A0G2JQ95|A0A0G2JQ95_HUMAN" 4 1773.7377 1.1 145811 16073 3 1773.740056 592.2532 Protein LSM14 homolog A OS=Homo sapiens OX=9606 GN=LSM14A PE=1 SV=3 4.23 2912.1 - 912589 - - - 1.3503 - 2.239 0.548 - 214.3 1 2 1 0.0024 14 0 0 0 2.16E+07 1.97E+07 - - - 6.791 1 221125_WJC_METTL3_EV_vs_WT_F10.16088.16088.3 2.48E-12 17/128 K.AAEAAPPTQEAQGETEPTEQAPDALEQAADTSR[166.11].R "sp|Q8N163|CCAR2_HUMAN,tr|H0YB24|H0YB24_HUMAN,tr|G3V119|G3V119_HUMAN" 3 3389.5371 1.59 145817 16088 3 3389.542009 1130.853 Cell cycle and apoptosis regulator protein 2 OS=Homo sapiens OX=9606 GN=CCAR2 PE=1 SV=2 3.67 2914.2 - 385713 - - - 1.4627 - 3.798 0.659 - 177.9 1 2 0 0.005 33 0 0 0 1.78E+07 1.12E+07 - - - 8.956 0.9998 221125_WJC_METTL3_EV_vs_WT_F10.16094.16094.4 1.95E-10 18/144 R.KLVFDDFC[160.03]DSSNVSNKDSSEDDISR.S sp|Q5W0B1|OBI1_HUMAN 1 2878.2563 0.19 145819 16094 4 2878.264542 720.5714 ORC ubiquitin ligase 1 OS=Homo sapiens OX=9606 GN=OBI1 PE=1 SV=1 4.04 2915 - 192995 - - - 2.8597 - 3.749 0.577 - 233.3 1 2 1 0.0082 25 0 0 0 3.53E+06 1.90E+07 - - - 4.6663 1 221125_WJC_METTL3_EV_vs_WT_F10.16111.16111.4 3.80E-13 21/210 K.GVSEAAVLK[136.11]PSEELPAEATSSVEPEK[136.11]DSGSAAEAPR[166.11].- sp|O95104|SCAF4_HUMAN 1 3620.7904 0.82 145828 16111 4 3620.793106 906.2049 SR-related and CTD-associated factor 4 OS=Homo sapiens OX=9606 GN=SCAF4 PE=1 SV=3 4.22 2917.3 - 389921 - - - 0.757 - 4.113 0.672 - 135.3 1 2 1 0.0027 36 0 0 0 1.64E+07 2.01E+07 - - - 5.4912 0.998 221125_WJC_METTL3_EV_vs_WT_F10.16112.16112.4 0.000311 Oct-96 K.QVK[136.11]PYVEEGLHPQIIIR[166.11].A "sp|Q99832|TCPH_HUMAN,tr|F8WAM2|F8WAM2_HUMAN" 2 2036.1538 0.13 145829 16112 4 2036.154229 510.0457 T-complex protein 1 subunit eta OS=Homo sapiens OX=9606 GN=CCT7 PE=1 SV=2 6.76 2917.4 - 147432 - - - 0.2274 - 1.669 0.272 - 62.4 1 2 0 0.0005 17 0 0 0 1.04E+06 8.24E+06 - - - 1.7712 0.9601 221125_WJC_METTL3_EV_vs_WT_F10.16118.16118.4 0.125 8/114 R.AISHEHSPSDLEAHFVPLVK[136.11].R "sp|P30153|2AAA_HUMAN,tr|C9J9C1|C9J9C1_HUMAN" 2 2220.1419 -1 145832 16118 4 2220.142083 556.0427 Serine\threonine-protein phosphatase 2A 65 kDa regulatory subunit A alpha isoform OS=Homo sapiens OX=9606 GN=PPP2R1A PE=1 SV=4 5.75 2918.2 - 197011 - - - 0.0973 - 1.397 0.156 - 32.5 1 2 0 0.0002 20 0 0 0 0.00E+00 0.00E+00 - - - 0.6955 0.9525 221125_WJC_METTL3_EV_vs_WT_F10.16121.16121.4 3.84E-07 13/102 N.HNILQIVDVC[160.03]HDVEKDEK.L "sp|P17844|DDX5_HUMAN,tr|A0A7I2V5F5|A0A7I2V5F5_HUMAN,tr|J3KRZ1|J3KRZ1_HUMAN,tr|J3QSF1|J3QSF1_HUMAN,tr|A0A7I2V507|A0A7I2V507_HUMAN,tr|J3KTA4|J3KTA4_HUMAN,tr|A0A0G2JLI4|A0A0G2JLI4_HUMAN,tr|A0A7I2V2S0|A0A7I2V2S0_HUMAN" 8 2190.0739 1.64 145833 16121 4 2190.0786 548.5258 Probable ATP-dependent RNA helicase DDX5 OS=Homo sapiens OX=9606 GN=DDX5 PE=1 SV=1 4.8 2918.6 - 290355 - - - 2.1383 - 2.58 0.455 - 161.8 1 1 1 0.0047 18 0 0 0 9.35E+06 5.69E+06 - - - 3.5097 0.9985 221125_WJC_METTL3_EV_vs_WT_F10.16123.16123.3 0.00471 Jul-36 R.K[136.11]QDSGHLDLR[166.11].N "sp|Q86U44|MTA70_HUMAN,tr|B4E349|B4E349_HUMAN,tr|F5H6D8|F5H6D8_HUMAN,tr|B4DTN4|B4DTN4_HUMAN" 4 1185.6221 0.001 145835 16123 3 1185.6246 396.2146 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 6.75 2918.9 - 87638.3 - - - 2.1044 - 1.626 0.321 - 78.1 1 2 0 0.0025 10 0 0 0 0.00E+00 4.41E+06 - - - 3.5378 0.9998 221125_WJC_METTL3_EV_vs_WT_F10.16127.16127.4 4.21E-06 13/138 R.QDGSQEAPEAPLSSELEPFHPKPK.L "sp|Q14676|MDC1_HUMAN,tr|H0Y6Z8|H0Y6Z8_HUMAN" 2 2617.266 2.38 145837 16127 4 2617.276772 655.3238 Mediator of DNA damage checkpoint protein 1 OS=Homo sapiens OX=9606 GN=MDC1 PE=1 SV=3 4.57 2919.4 - 364215 - - - 4.1115 - 2.362 0.55 - 85.6 1 2 0 0.0108 24 0 0 0 1.11E+07 4.66E+06 - - - 4.2861 1 221125_WJC_METTL3_EV_vs_WT_F10.16134.16134.4 1.52E-14 23/210 K.GVSEAAVLKPSEELPAEATSSVEPEKDSGSAAEAPR.- sp|O95104|SCAF4_HUMAN 1 3594.7537 0.82 145840 16134 4 3594.755753 899.6957 SR-related and CTD-associated factor 4 OS=Homo sapiens OX=9606 GN=SCAF4 PE=1 SV=3 4.22 2920.4 - 348753 - - - 0.5725 - 4.882 0.646 - 218.4 1 2 1 0.0021 36 0 0 0 1.64E+07 2.01E+07 - - - 5.3156 0.8709 221125_WJC_METTL3_EV_vs_WT_F10.16136.16136.4 0.000327 10/102 N.HNILQIVDVC[160.03]HDVEK[136.11]DEK[136.11].L "sp|P17844|DDX5_HUMAN,tr|A0A7I2V5F5|A0A7I2V5F5_HUMAN,tr|J3KRZ1|J3KRZ1_HUMAN,tr|J3QSF1|J3QSF1_HUMAN,tr|A0A7I2V507|A0A7I2V507_HUMAN,tr|J3KTA4|J3KTA4_HUMAN,tr|A0A0G2JLI4|A0A0G2JLI4_HUMAN,tr|A0A7I2V2S0|A0A7I2V2S0_HUMAN" 8 2206.1023 1.97 145841 16136 4 2206.110463 552.5329 Probable ATP-dependent RNA helicase DDX5 OS=Homo sapiens OX=9606 GN=DDX5 PE=1 SV=1 4.8 2920.6 - 145493 - - - 3.6925 - 2.155 0.463 - 97.4 1 1 1 0.0081 18 0 0 0 1.70E+07 8.65E+06 - - - 3.5167 1 221125_WJC_METTL3_EV_vs_WT_F10.16138.16138.3 2.54E-08 14/108 K.GDSGVDTQNSEGNADEEDPLGPNC[160.03]YYDK.T "sp|Q8ND56|LS14A_HUMAN,tr|A0A096LP11|A0A096LP11_HUMAN,tr|A0A140TA76|A0A140TA76_HUMAN,tr|K7EMZ9|K7EMZ9_HUMAN,tr|A0A0G2JQ95|A0A0G2JQ95_HUMAN" 5 3045.2054 1.29 145842 16138 3 3045.218558 1016.0757 Protein LSM14 homolog A OS=Homo sapiens OX=9606 GN=LSM14A PE=1 SV=3 3.54 2920.9 - 243308 - - - 4.3215 - 3.304 0.776 - 123.8 1 2 0 0.0132 28 0 0 0 1.10E+07 8.56E+06 - - - 9.9376 0.9994 221125_WJC_METTL3_EV_vs_WT_F10.16139.16139.4 9.12E-05 11/138 R.QDGSQEAPEAPLSSELEPFHPK[136.11]PK[136.11].L "sp|Q14676|MDC1_HUMAN,tr|H0Y6Z8|H0Y6Z8_HUMAN" 2 2633.2944 2.32 145843 16139 4 2633.306492 659.3309 Mediator of DNA damage checkpoint protein 1 OS=Homo sapiens OX=9606 GN=MDC1 PE=1 SV=3 4.57 2921 - 212221 - - - 4.5878 - 2.087 0.473 - 42.4 1 2 0 0.0121 24 0 0 0 1.05E+07 4.53E+06 - - - 3.5758 1 221125_WJC_METTL3_EV_vs_WT_F10.16158.16158.3 8.35E-10 14/108 K.GDSGVDTQNSEGNADEEDPLGPNC[160.03]YYDK[136.11].T "sp|Q8ND56|LS14A_HUMAN,tr|A0A096LP11|A0A096LP11_HUMAN,tr|A0A140TA76|A0A140TA76_HUMAN,tr|K7EMZ9|K7EMZ9_HUMAN,tr|A0A0G2JQ95|A0A0G2JQ95_HUMAN" 5 3053.2196 1.29 145851 16158 3 3053.22532 1018.7471 Protein LSM14 homolog A OS=Homo sapiens OX=9606 GN=LSM14A PE=1 SV=3 3.54 2923.6 - 256231 - - - 1.8741 - 2.928 0.736 - 115.6 1 2 0 0.0057 28 0 0 0 1.10E+07 8.56E+06 - - - 9.2157 0.9799 221125_WJC_METTL3_EV_vs_WT_F10.16161.16161.4 0.0134 Aug-96 K.EDTEEHHLR[166.11]DYFEEYGK[136.11].L "sp|P22626|ROA2_HUMAN,tr|A0A7I2YQN4|A0A7I2YQN4_HUMAN,tr|A0A7I2V4N0|A0A7I2V4N0_HUMAN,tr|A0A024RA28|A0A024RA28_HUMAN,tr|A0A7I2V4N1|A0A7I2V4N1_HUMAN,tr|A0A7I2V4I6|A0A7I2V4I6_HUMAN,tr|A0A087WUI2|A0A087WUI2_HUMAN,tr|A0A7I2V4S4|A0A7I2V4S4_HUMAN,tr|A0A7I2V323|A0A7I2V323_HUMAN,tr|A0A7I2V3P1|A0A7I2V3P1_HUMAN,tr|A0A7I2V3P7|A0A7I2V3P7_HUMAN" 11 2213.9621 1.6 145852 16161 4 2213.971502 554.4978 Heterogeneous nuclear ribonucleoproteins A2\B1 OS=Homo sapiens OX=9606 GN=HNRNPA2B1 PE=1 SV=2 4.48 2924 - 267150 - - - 4.2638 - 1.666 0.326 - 55.8 1 2 1 0.0094 17 0 0 0 2.00E+07 1.25E+07 - - - 2.2381 1 221125_WJC_METTL3_EV_vs_WT_F10.16163.16163.3 1.24E-06 14/120 R.K[136.11]YTELPHGAISEDQAVGPADIPC[160.03]DSTGQTST.- "sp|Q9H773|DCTP1_HUMAN,tr|H3BPN2|H3BPN2_HUMAN,tr|H3BSA6|H3BSA6_HUMAN" 3 3252.4972 0.62 145853 16163 3 3252.503574 1085.173 dCTP pyrophosphatase 1 OS=Homo sapiens OX=9606 GN=DCTPP1 PE=1 SV=1 4.1 2924.2 - 353750 - - - 1.9545 - 2.764 0.623 - 105 1 2 0 0.0064 31 0 0 0 3.09E+07 5.02E+07 - - - 7.8231 0.9999 221125_WJC_METTL3_EV_vs_WT_F10.16167.16167.3 0.000767 9/120 R.KYTELPHGAISEDQAVGPADIPC[160.03]DSTGQTST.- "sp|Q9H773|DCTP1_HUMAN,tr|H3BPN2|H3BPN2_HUMAN,tr|H3BSA6|H3BSA6_HUMAN" 3 3244.483 0.62 145855 16167 3 3244.487424 1082.5016 dCTP pyrophosphatase 1 OS=Homo sapiens OX=9606 GN=DCTPP1 PE=1 SV=1 4.1 2924.7 - 227817 - - - 1.3583 - 2.238 0.502 - 40.3 1 2 0 0.0044 31 0 0 0 3.09E+07 5.02E+07 - - - 5.9889 0.9946 221125_WJC_METTL3_EV_vs_WT_F10.16173.16173.4 0.0382 Jun-96 K.EDTEEHHLRDYFEEYGK.L "sp|P22626|ROA2_HUMAN,tr|A0A7I2YQN4|A0A7I2YQN4_HUMAN,tr|A0A7I2V4N0|A0A7I2V4N0_HUMAN,tr|A0A024RA28|A0A024RA28_HUMAN,tr|A0A7I2V4N1|A0A7I2V4N1_HUMAN,tr|A0A7I2V4I6|A0A7I2V4I6_HUMAN,tr|A0A087WUI2|A0A087WUI2_HUMAN,tr|A0A7I2V4S4|A0A7I2V4S4_HUMAN,tr|A0A7I2V323|A0A7I2V323_HUMAN,tr|A0A7I2V3P1|A0A7I2V3P1_HUMAN,tr|A0A7I2V3P7|A0A7I2V3P7_HUMAN" 11 2195.9396 1.61 145858 16173 4 2195.946076 549.9922 Heterogeneous nuclear ribonucleoproteins A2\B1 OS=Homo sapiens OX=9606 GN=HNRNPA2B1 PE=1 SV=2 4.48 2925.5 - 355490 - - - 2.9527 - 1.449 0.351 - 13.6 1 2 1 0.0065 17 0 0 0 2.00E+07 1.25E+07 - - - 2.4081 1 221125_WJC_METTL3_EV_vs_WT_F10.16191.16191.4 1.97E-07 13/180 R.K[136.11]YTELPHGAISEDQAVGPADIPC[160.03]DSTGQTST.- "sp|Q9H773|DCTP1_HUMAN,tr|H3BPN2|H3BPN2_HUMAN,tr|H3BSA6|H3BSA6_HUMAN" 3 3252.4972 0.42 145867 16191 4 3252.50229 814.1316 dCTP pyrophosphatase 1 OS=Homo sapiens OX=9606 GN=DCTPP1 PE=1 SV=1 4.1 2927.9 - 374136 - - - 1.5597 - 2.871 0.61 - 81.7 1 2 0 0.0051 31 0 0 0 8.66E+06 2.06E+07 - - - 4.8546 1 221125_WJC_METTL3_EV_vs_WT_F10.16192.16192.4 4.54E-09 19/114 K.R[166.11]GLLQDDAHPTLVTYADHSK[136.11].L "sp|Q86U44|MTA70_HUMAN,tr|F5H6D8|F5H6D8_HUMAN,tr|H0YFV6|H0YFV6_HUMAN,tr|B4DTN4|B4DTN4_HUMAN" 4 2254.1461 0.01 145868 16192 4 2254.150649 564.5438 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 5.99 2928.1 - 412409 - - - 2.0114 - 3.231 0.555 - 341.2 1 2 0 0.0045 20 0 0 0 2.27E+05 2.06E+07 - - - 4.4476 1 221125_WJC_METTL3_EV_vs_WT_F10.16225.16225.4 2.97E-05 14/84 K.HTTSIFDDFSHYEKR.Q sp|Q9Y5A9|YTHD2_HUMAN 1 1881.8646 1.16 145880 16225 4 1881.864025 471.4734 YTH domain-containing family protein 2 OS=Homo sapiens OX=9606 GN=YTHDF2 PE=1 SV=2 6 2932.8 - 177245 - - - -0.2928 - 3.035 0.577 - 251.5 1 2 0 -0.0006 15 0 0 0 1.30E+07 1.12E+07 - - - 4.6453 1 221125_WJC_METTL3_EV_vs_WT_F10.16233.16233.3 1.64E-09 15/96 K.NDQDTWDYTNPNLSGQGDPGSNPNK.R "sp|P14866|HNRPL_HUMAN,tr|A0A3B3ITJ4|A0A3B3ITJ4_HUMAN,tr|M0QXS5|M0QXS5_HUMAN" 3 2733.1539 1.72 145885 16233 3 2733.152509 912.0586 Heterogeneous nuclear ribonucleoprotein L OS=Homo sapiens OX=9606 GN=HNRNPL PE=1 SV=2 3.77 2933.9 - 240837 - - - -0.5071 - 2.537 0.757 - 132.7 1 2 0 -0.0014 25 0 0 0 1.47E+07 8.56E+06 - - - 9.1213 1 221125_WJC_METTL3_EV_vs_WT_F10.16238.16238.4 2.33E-06 29/180 R.PC[160.03]LQPC[160.03]EHPEPC[160.03]PRPEPIPLPAPC[160.03]PSPEPC[160.03]R.E sp|Q5T749|KPRP_HUMAN 1 3670.6612 999 145886 16238 4 3670.664097 918.6726 Keratinocyte proline-rich protein OS=Homo sapiens OX=9606 GN=KPRP PE=1 SV=1 4.91 2934.6 - 700970 - - - 0.8012 - 4.754 0.692 - 346.7 1 1 0 0.0029 31 0 0 0 4.90E+07 0.00E+00 - - - 5.7222 1 221125_WJC_METTL3_EV_vs_WT_F10.16249.16249.3 2.58E-06 16/96 K.NDQDTWDYTNPNLSGQGDPGSNPNK[136.11].R "sp|P14866|HNRPL_HUMAN,tr|A0A3B3ITJ4|A0A3B3ITJ4_HUMAN,tr|M0QXS5|M0QXS5_HUMAN" 3 2741.1681 1.72 145892 16249 3 2741.172126 914.73 Heterogeneous nuclear ribonucleoprotein L OS=Homo sapiens OX=9606 GN=HNRNPL PE=1 SV=2 3.77 2936.1 - 322477 - - - 1.4705 - 2.834 0.707 - 167 1 2 0 0.004 25 0 0 0 1.47E+07 8.56E+06 - - - 8.8178 1 221125_WJC_METTL3_EV_vs_WT_F10.16257.16257.4 1.67E-09 14/84 K.HTTSIFDDFSHYEK[136.11]R[166.11].Q sp|Q9Y5A9|YTHD2_HUMAN 1 1899.887 1.16 145895 16257 4 1899.886083 475.979 YTH domain-containing family protein 2 OS=Homo sapiens OX=9606 GN=YTHDF2 PE=1 SV=2 6 2937.1 - 361806 - - - -0.5069 - 2.934 0.612 - 155.3 1 2 0 -0.001 15 0 0 0 1.30E+07 1.12E+07 - - - 4.9377 0.8833 221125_WJC_METTL3_EV_vs_WT_F10.16321.16321.4 0.0299 8/120 K.HGITELHPDVVSYVSHATQQR.L "sp|O00268|TAF4_HUMAN,tr|A0A0G2JRY5|A0A0G2JRY5_HUMAN" 2 2373.1826 1.77 145925 16321 4 2373.194076 594.3029 Transcription initiation factor TFIID subunit 4 OS=Homo sapiens OX=9606 GN=TAF4 PE=1 SV=2 6.26 2945.7 - 106502 - - - 4.8542 - 1.504 0.205 - 26.4 1 2 0 0.0115 21 0 0 0 3.05E+07 1.72E+07 - - - 1.1421 0.9996 221125_WJC_METTL3_EV_vs_WT_F10.16337.16337.4 0.000359 10/120 K.HGITELHPDVVSYVSHATQQR[166.11].L "sp|O00268|TAF4_HUMAN,tr|A0A0G2JRY5|A0A0G2JRY5_HUMAN" 2 2383.1908 1.8 145934 16337 4 2383.198349 596.805 Transcription initiation factor TFIID subunit 4 OS=Homo sapiens OX=9606 GN=TAF4 PE=1 SV=2 6.26 2947.9 - 117693 - - - 3.1567 - 2.118 0.421 - 47 1 2 0 0.0075 21 0 0 0 3.02E+07 1.68E+07 - - - 3.1364 0.9996 221125_WJC_METTL3_EV_vs_WT_F10.16356.16356.4 1.01E-06 20/150 R.SPSPC[160.03]WGPNPVPYPGDLGC[160.03]HESSPHR.L sp|Q5T749|KPRP_HUMAN 1 2886.2602 290.74 145947 16356 4 2886.275749 722.5723 Keratinocyte proline-rich protein OS=Homo sapiens OX=9606 GN=KPRP PE=1 SV=1 5.94 2950.6 - 467437 - - - 5.3762 - 2.511 0.565 - 147 1 2 0 0.0155 26 0 0 0 1.14E+08 3.91E+05 - - - 4.4299 0.9997 221125_WJC_METTL3_EV_vs_WT_F10.16363.16363.3 8.69E-08 Oct-64 R.HDGSEPC[160.03]VDVLFGDGHR[166.11].L sp|Q96EL3|RM53_HUMAN 1 1905.8303 1.36 145951 16363 3 1905.841112 636.2841 "39S ribosomal protein L53, mitochondrial OS=Homo sapiens OX=9606 GN=MRPL53 PE=1 SV=1" 4.64 2951.5 - 105116 - - - 5.6574 - 2.144 0.7 - 131.9 1 2 0 0.0108 17 0 0 0 4.29E+06 3.15E+06 - - - 8.2681 0.9902 221125_WJC_METTL3_EV_vs_WT_F10.16365.16365.3 1.16E-07 15/84 E.TQITQIEHEVSSSGQEVQSSAK.E "sp|P35527|K1C9_HUMAN,tr|K7EQQ3|K7EQQ3_HUMAN" 2 2372.1456 999 145952 16365 3 2372.155639 791.7225 "Keratin, type I cytoskeletal 9 OS=Homo sapiens OX=9606 GN=KRT9 PE=1 SV=3" 4.75 2951.8 - 238671 - - - 4.2481 - 3.442 0.617 - 168.3 1 1 0 0.0101 22 0 0 0 6.19E+06 0.00E+00 - - - 8.3466 0.9981 221125_WJC_METTL3_EV_vs_WT_F10.16374.16374.4 2.36E-10 15/180 R.HRGQAAQPEPSTGFTATPPAPDSPQEPLVLR.L "sp|Q9BVT8|TMUB1_HUMAN,tr|C9JE12|C9JE12_HUMAN,tr|A0A590UJA9|A0A590UJA9_HUMAN,tr|C9JCW7|C9JCW7_HUMAN" 4 3251.6323 2.1 145955 16374 4 3251.653428 813.9154 Transmembrane and ubiquitin-like domain-containing protein 1 OS=Homo sapiens OX=9606 GN=TMUB1 PE=1 SV=1 5.45 2953.1 - 140089 - - - 6.4857 - 3.154 0.615 - 100.1 1 2 1 0.0211 31 0 0 0 3.71E+06 1.77E+06 - - - 4.9222 0.8378 221125_WJC_METTL3_EV_vs_WT_F10.16376.16376.4 0.00041 13/138 K.QISNLQQSISDAEQRGENALKDAK.N sp|P04264|K2C1_HUMAN 1 2642.326 9.98 145956 16376 4 2643.32684 661.5888 "Keratin, type II cytoskeletal 1 OS=Homo sapiens OX=9606 GN=KRT1 PE=1 SV=6" 4.78 2953.3 - 383298 - - - 378.7776 - 1.982 0.301 - 67.1 1 2 2 1.0009 24 0 0 0 6.82E+06 6.83E+05 - - - 1.7882 0.9985 221125_WJC_METTL3_EV_vs_WT_F10.16384.16384.4 8.20E-05 12/102 K.R[166.11]PLDDGVGNQLGALVHQR[166.11].T sp|Q96I24|FUBP3_HUMAN 1 1964.0455 2.2 145960 16384 4 1964.055963 492.0187 Far upstream element-binding protein 3 OS=Homo sapiens OX=9606 GN=FUBP3 PE=1 SV=2 6.75 2954.5 - 98801.7 - - - 5.3293 - 2.065 0.434 - 127.5 1 2 0 0.0105 18 0 0 0 2.95E+07 1.34E+07 - - - 3.249 0.9999 221125_WJC_METTL3_EV_vs_WT_F10.16386.16386.3 2.10E-06 Sep-64 R.HDGSEPC[160.03]VDVLFGDGHR.L sp|Q96EL3|RM53_HUMAN 1 1895.8221 1.06 145962 16386 3 1895.829112 632.948 "39S ribosomal protein L53, mitochondrial OS=Homo sapiens OX=9606 GN=MRPL53 PE=1 SV=1" 4.64 2954.7 - 90108.3 - - - 3.7198 - 2.05 0.611 - 97.1 1 2 0 0.0071 17 0 0 0 4.54E+06 4.27E+06 - - - 7.1636 0.9998 221125_WJC_METTL3_EV_vs_WT_F10.16390.16390.3 5.69E-09 16/68 K.R[166.11]PLDDGVGNQLGALVHQR[166.11].T sp|Q96I24|FUBP3_HUMAN 1 1964.0455 1.97 145963 16390 3 1964.055904 655.6891 Far upstream element-binding protein 3 OS=Homo sapiens OX=9606 GN=FUBP3 PE=1 SV=2 6.75 2955.5 - 116716 - - - 5.2993 - 3.447 0.569 - 337.7 1 2 0 0.0104 18 0 0 0 2.31E+07 1.17E+07 - - - 7.9624 0.999 221125_WJC_METTL3_EV_vs_WT_F10.16402.16402.3 0.0094 8/100 R.SPSPC[160.03]WGPNPVPYPGDLGC[160.03]HESSPHR.L sp|Q5T749|KPRP_HUMAN 1 2886.2602 2.49 145968 16402 3 2886.272218 963.094 Keratinocyte proline-rich protein OS=Homo sapiens OX=9606 GN=KPRP PE=1 SV=1 5.94 2957.2 - 129324 - - - 4.1528 - 1.505 0.507 - 35.3 1 2 0 0.012 26 0 0 0 5.74E+06 2.31E+06 - - - 5.1297 1 221125_WJC_METTL3_EV_vs_WT_F10.16419.16419.4 1.64E-08 16/114 K.R[166.11]GLLQDDAHPTLVTYADHSK[136.11].L "sp|Q86U44|MTA70_HUMAN,tr|F5H6D8|F5H6D8_HUMAN,tr|H0YFV6|H0YFV6_HUMAN,tr|B4DTN4|B4DTN4_HUMAN" 4 2254.1461 0.02 145977 16419 4 2254.158535 564.5438 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 5.99 2959.6 - 235963 - - - 5.5098 - 3.258 0.624 - 206.2 1 2 0 0.0124 20 0 0 0 2.50E+05 1.27E+07 - - - 5.0487 0.9968 221125_WJC_METTL3_EV_vs_WT_F10.16423.16423.3 7.97E-05 15/132 K.TQPSSQPLQSGQVLPSATPTPSAPPTSQQELQAK[136.11].L sp|Q9HCD5|NCOA5_HUMAN 1 3493.778 2.45 145978 16423 3 3493.80318 1165.5999 Nuclear receptor coactivator 5 OS=Homo sapiens OX=9606 GN=NCOA5 PE=1 SV=2 5.66 2960.3 - 176294 - - - 7.2051 - 2.807 0.449 - 80.2 1 2 0 0.0252 34 0 0 0 1.35E+08 5.52E+07 - - - 5.9135 1 221125_WJC_METTL3_EV_vs_WT_F10.16425.16425.3 7.05E-10 31/132 K.TQPSSQPLQSGQVLPSATPTPSAPPTSQQELQAK.L sp|Q9HCD5|NCOA5_HUMAN 1 3485.7638 2.46 145979 16425 3 3485.783339 1162.9285 Nuclear receptor coactivator 5 OS=Homo sapiens OX=9606 GN=NCOA5 PE=1 SV=2 5.66 2960.6 - 487976 - - - 5.6034 - 3.974 0.643 - 560.5 1 2 0 0.0195 34 0 0 0 1.36E+08 5.53E+07 - - - 8.8778 0.998 221125_WJC_METTL3_EV_vs_WT_F10.16428.16428.4 9.02E-06 32/198 K.TQPSSQPLQSGQVLPSATPTPSAPPTSQQELQAK.L sp|Q9HCD5|NCOA5_HUMAN 1 3485.7638 2.07 145980 16428 4 3485.783478 872.4482 Nuclear receptor coactivator 5 OS=Homo sapiens OX=9606 GN=NCOA5 PE=1 SV=2 5.66 2961.1 - 900122 - - - 5.6432 - 3.935 0.413 - 323.2 1 2 0 0.0197 34 0 0 0 1.23E+08 5.96E+07 - - - 3.2238 0.9967 221125_WJC_METTL3_EV_vs_WT_F10.16430.16430.3 0.00113 7/112 K.QKGDTPASATAGDTLSVPAPAVQPEESLK.T "tr|A0A087WYS0|A0A087WYS0_HUMAN,tr|C9J406|C9J406_HUMAN,tr|H7C463|H7C463_HUMAN" 3 2864.4403 1.94 145982 16430 3 2864.447228 955.8207 MICOS complex subunit MIC60 OS=Homo sapiens OX=9606 GN=IMMT PE=1 SV=1 4.32 2961.4 - 111605 - - - 2.4022 - 1.526 0.426 - 23.7 1 2 1 0.0069 29 0 0 0 1.89E+06 9.74E+05 - - - 4.2599 0.9971 221125_WJC_METTL3_EV_vs_WT_F10.16435.16435.3 0.00222 Oct-68 R.VAPEEHPVLLTEAPLNPK.A "sp|P63261|ACTG_HUMAN,sp|P60709|ACTB_HUMAN,tr|A0A804GS07|A0A804GS07_HUMAN,tr|I3L3I0|I3L3I0_HUMAN,tr|G5E9R0|G5E9R0_HUMAN,tr|E7EVS6|E7EVS6_HUMAN,tr|A0A6Q8PFE4|A0A6Q8PFE4_HUMAN,tr|J3KT65|J3KT65_HUMAN,tr|I3L3R2|I3L3R2_HUMAN,tr|K7EM38|K7EM38_HUMAN,tr|A0A6Q8PH58|A0A6Q8PH58_HUMAN,tr|I3L1U9|I3L1U9_HUMAN,tr|A0A2R8Y793|A0A2R8Y793_HUMAN,tr|I3L4N8|I3L4N8_HUMAN,tr|A0A2R8YGF8|A0A2R8YGF8_HUMAN" 15 1953.0571 1.27 145984 16435 3 1953.064792 652.0263 "Actin, cytoplasmic 2 OS=Homo sapiens OX=9606 GN=ACTG1 PE=1 SV=1" 4.75 2962.1 - 141099 - - - 3.9241 - 2.239 0.312 - 134.4 1 2 0 0.0077 18 0 0 0 8.09E+06 6.35E+06 - - - 4.0235 0.9953 221125_WJC_METTL3_EV_vs_WT_F10.16451.16451.3 4.20E-05 Jul-52 K.HWPFMVVNDAGR[166.11]PK[136.11].V "sp|P11142|HSP7C_HUMAN,tr|E9PQQ4|E9PQQ4_HUMAN,tr|E9PNE6|E9PNE6_HUMAN,tr|E9PKE3|E9PKE3_HUMAN,tr|E9PN89|E9PN89_HUMAN,tr|E9PLF4|E9PLF4_HUMAN,tr|E9PK54|E9PK54_HUMAN,tr|E9PN25|E9PN25_HUMAN,tr|E9PPY6|E9PPY6_HUMAN,tr|E9PQK7|E9PQK7_HUMAN" 10 1670.847 0.09 145990 16451 3 1670.857062 557.9563 Heat shock cognate 71 kDa protein OS=Homo sapiens OX=9606 GN=HSPA8 PE=1 SV=1 8.75 2964.4 - 38629.9 - - - 6.0005 - 1.514 0.467 - 58.8 1 2 0 0.01 14 0 0 0 2.53E+06 2.92E+07 - - - 4.846 1 221125_WJC_METTL3_EV_vs_WT_F10.16455.16455.4 1.38E-14 30/234 R.ESPRPLQLPGAEGPAISDGEEGGGEPGAGGGAAGAAGAGR.R "sp|Q6PKG0|LARP1_HUMAN,tr|A0A0B4J210|A0A0B4J210_HUMAN" 2 3526.6673 0.21 145992 16455 4 3526.669856 882.6741 La-related protein 1 OS=Homo sapiens OX=9606 GN=LARP1 PE=1 SV=2 4.14 2964.9 - 318298 - - - 0.7304 - 4.998 0.723 - 383.2 1 2 0 0.0026 40 0 0 0 1.20E+07 5.71E+07 - - - 5.9827 1 221125_WJC_METTL3_EV_vs_WT_F10.16474.16474.3 7.99E-10 17/156 R.ESPRPLQLPGAEGPAISDGEEGGGEPGAGGGAAGAAGAGR.R "sp|Q6PKG0|LARP1_HUMAN,tr|A0A0B4J210|A0A0B4J210_HUMAN" 2 3526.6673 1.44 146003 16474 3 3526.67201 1176.563 La-related protein 1 OS=Homo sapiens OX=9606 GN=LARP1 PE=1 SV=2 4.14 2967.6 - 153891 - - - 1.3412 - 3.68 0.703 - 104.9 1 2 0 0.0047 40 0 0 0 4.29E+06 2.98E+06 - - - 9.374 0.9986 221125_WJC_METTL3_EV_vs_WT_F10.16475.16475.3 0.000438 Dec-68 R.VAPEEHPVLLTEAPLNPK[136.11].A "sp|P63261|ACTG_HUMAN,sp|P60709|ACTB_HUMAN,tr|A0A804GS07|A0A804GS07_HUMAN,tr|I3L3I0|I3L3I0_HUMAN,tr|G5E9R0|G5E9R0_HUMAN,tr|E7EVS6|E7EVS6_HUMAN,tr|A0A6Q8PFE4|A0A6Q8PFE4_HUMAN,tr|J3KT65|J3KT65_HUMAN,tr|I3L3R2|I3L3R2_HUMAN,tr|K7EM38|K7EM38_HUMAN,tr|A0A6Q8PH58|A0A6Q8PH58_HUMAN,tr|I3L1U9|I3L1U9_HUMAN,tr|A0A2R8Y793|A0A2R8Y793_HUMAN,tr|I3L4N8|I3L4N8_HUMAN,tr|A0A2R8YGF8|A0A2R8YGF8_HUMAN" 15 1961.0713 1.27 146004 16475 3 1961.080948 654.6977 "Actin, cytoplasmic 2 OS=Homo sapiens OX=9606 GN=ACTG1 PE=1 SV=1" 4.75 2967.7 - 176792 - - - 4.9055 - 2.254 0.424 - 173.2 1 2 0 0.0096 18 0 0 0 8.09E+06 6.35E+06 - - - 5.2882 0.9971 221125_WJC_METTL3_EV_vs_WT_F10.16476.16476.2 0.00248 16-Aug R.VLDELTLTK.A "sp|P13645|K1C10_HUMAN,tr|A0A1B0GVI3|A0A1B0GVI3_HUMAN" 2 1030.591 999 146005 16476 2 1030.594784 516.3028 "Keratin, type I cytoskeletal 10 OS=Homo sapiens OX=9606 GN=KRT10 PE=1 SV=6" 4.37 2967.8 - 137730 - - - 3.6455 - 1.6 0.387 - 177.1 1 2 0 0.0038 9 0 0 0 1.17E+07 0.00E+00 - - - 3.2579 0.9864 221125_WJC_METTL3_EV_vs_WT_F10.16478.16478.3 0.000163 7/156 R.ESPR[166.11]PLQLPGAEGPAISDGEEGGGEPGAGGGAAGAAGAGR[166.11].R "sp|Q6PKG0|LARP1_HUMAN,tr|A0A0B4J210|A0A0B4J210_HUMAN" 2 3546.6838 1.44 146007 16478 3 3546.706932 1183.2352 La-related protein 1 OS=Homo sapiens OX=9606 GN=LARP1 PE=1 SV=2 4.14 2968.1 - 87135.3 - - - 6.5165 - 1.62 0.409 - 17.5 1 2 0 0.0231 40 0 0 0 4.29E+06 2.98E+06 - - - 4.2034 1 221125_WJC_METTL3_EV_vs_WT_F10.16490.16490.3 4.65E-07 Oct-52 R.SDSFENPVLQQHFR[166.11].N "sp|P12956|XRCC6_HUMAN,tr|B1AHC9|B1AHC9_HUMAN" 2 1712.8146 0.51 146015 16490 3 1712.816954 571.9455 X-ray repair cross-complementing protein 6 OS=Homo sapiens OX=9606 GN=XRCC6 PE=1 SV=2 5.3 2969.7 - 87233.8 - - - 1.3726 - 2.13 0.596 - 149.3 1 2 0 0.0024 14 0 0 0 2.15E+06 4.23E+06 - - - 7.1936 0.962 221125_WJC_METTL3_EV_vs_WT_F10.16502.16502.4 0.144 4/138 K.EKETNDDNYGPGPSLRPPNVAC[160.03]WR.D "sp|Q9Y520|PRC2C_HUMAN,tr|E7EPN9|E7EPN9_HUMAN" 2 2771.2722 1.19 146021 16502 4 2771.274121 693.8253 Protein PRRC2C OS=Homo sapiens OX=9606 GN=PRRC2C PE=1 SV=4 4.78 2971.4 - 159448 - - - 0.7018 - 1.238 0.216 - 10.3 1 2 1 0.0019 24 0 0 0 9.47E+06 7.95E+06 - - - 1.1741 0.9999 221125_WJC_METTL3_EV_vs_WT_F10.16509.16509.4 2.27E-07 15/204 K.IINLDNESQTTSSSNNEK[136.11]PGEQEK[136.11]EEDIAVLAEEK[136.11].L sp|Q8TAF3|WDR48_HUMAN 1 3911.8822 0.41 146024 16509 4 3911.889984 978.9778 WD repeat-containing protein 48 OS=Homo sapiens OX=9606 GN=WDR48 PE=1 SV=1 4.04 2972.5 - 232279 - - - 1.9873 - 3.129 0.61 - 89.6 1 2 1 0.0078 35 0 0 0 1.57E+06 3.84E+06 - - - 4.8715 0.8762 221125_WJC_METTL3_EV_vs_WT_F10.16534.16534.4 0.000688 11/138 E.VSNRFSGVPDRFSGSGSGTDFTLK.L "sp|A0A075B6S2|KVD29_HUMAN,sp|A0A0A0MRZ7|KVD26_HUMAN" 2 2517.2248 7.19 146036 16534 4 2517.230968 630.3135 Immunoglobulin kappa variable 2D-29 OS=Homo sapiens OX=9606 GN=IGKV2D-29 PE=3 SV=1 8.72 2975.9 - 484948 - - - 2.4444 - 2.119 0.406 - 56.1 1 1 2 0.0062 24 0 0 0 2.67E+07 3.71E+06 - - - 2.9991 1 221125_WJC_METTL3_EV_vs_WT_F10.16540.16540.4 0.0014 15/168 K.IQIASESSGIPER[166.11]PC[160.03]VLTGTPESIEQAK[136.11]R[166.11].L sp|Q96I24|FUBP3_HUMAN 1 3180.6443 2.01 146039 16540 4 3180.646278 796.1684 Far upstream element-binding protein 3 OS=Homo sapiens OX=9606 GN=FUBP3 PE=1 SV=2 4.95 2976.7 - 341741 - - - 0.6165 - 2.776 0.49 - 96.8 1 2 0 0.002 29 0 0 0 3.01E+07 1.49E+07 - - - 3.8051 1 221125_WJC_METTL3_EV_vs_WT_F10.16541.16541.3 4.01E-10 9/116 K.TGQEYK[136.11]PGNPPAEIGQNISSNSSASILESK[136.11].S "sp|P07814|SYEP_HUMAN,tr|V9GYZ6|V9GYZ6_HUMAN" 2 3118.539 0.94 146040 16541 3 3118.540581 1040.5203 Bifunctional glutamate\proline--tRNA ligase OS=Homo sapiens OX=9606 GN=EPRS1 PE=1 SV=5 4.78 2976.8 - 202690 - - - 0.5224 - 2.92 0.636 - 35.4 1 2 0 0.0016 30 0 0 0 1.14E+07 1.22E+07 - - - 8.0956 1 221125_WJC_METTL3_EV_vs_WT_F10.16548.16548.4 6.94E-12 23/168 K.IQIASESSGIPERPC[160.03]VLTGTPESIEQAKR.L sp|Q96I24|FUBP3_HUMAN 1 3152.6136 2.01 146045 16548 4 3152.61343 789.1607 Far upstream element-binding protein 3 OS=Homo sapiens OX=9606 GN=FUBP3 PE=1 SV=2 4.95 2977.7 - 1.02E+06 - - - -0.0466 - 3.87 0.556 - 204.6 1 2 0 -0.0001 29 0 0 0 3.01E+07 1.49E+07 - - - 4.4824 1 221125_WJC_METTL3_EV_vs_WT_F10.16554.16554.3 0.000231 20/116 K.TGQEYKPGNPPAEIGQNISSNSSASILESK.S "sp|P07814|SYEP_HUMAN,tr|V9GYZ6|V9GYZ6_HUMAN" 2 3102.5106 1 146049 16554 3 3102.514207 1035.1775 Bifunctional glutamate\proline--tRNA ligase OS=Homo sapiens OX=9606 GN=EPRS1 PE=1 SV=5 4.78 2978.6 - 267158 - - - 1.1781 - 4.321 0.658 - 319.8 1 2 0 0.0037 30 0 0 0 1.30E+08 1.30E+08 - - - 9.242 0.9997 221125_WJC_METTL3_EV_vs_WT_F10.16564.16564.4 1.93E-08 17/150 K.K[136.11]PLPDHVSIVEPK[136.11]DEILPTTPISEQK[136.11].G "sp|P23396|RS3_HUMAN,tr|H0YEU2|H0YEU2_HUMAN,tr|E9PSF4|E9PSF4_HUMAN,tr|E9PL09|E9PL09_HUMAN,tr|E9PPU1|E9PPU1_HUMAN" 5 2933.6176 0.77 146055 16564 4 2933.628155 734.4117 40S ribosomal protein S3 OS=Homo sapiens OX=9606 GN=RPS3 PE=1 SV=2 4.9 2979.9 - 222504 - - - 3.6014 - 3.648 0.566 - 150.2 1 2 1 0.0106 26 0 0 0 8.49E+07 1.10E+08 - - - 4.5578 0.957 221125_WJC_METTL3_EV_vs_WT_F10.16568.16568.4 1.22 10/156 R.LNEQEGVPSVFNPPPSR[166.11]PLQVNTADHR[166.11].L sp|Q96CS3|FAF2_HUMAN 1 3017.5222 1.15 146057 16568 4 3017.529339 755.3878 FAS-associated factor 2 OS=Homo sapiens OX=9606 GN=FAF2 PE=1 SV=2 5.45 2980.4 - 243699 - - - 2.3586 - 1.898 0.169 - 45.3 1 2 0 0.0071 27 0 0 0 1.09E+07 9.49E+06 - - - 0.8955 0.9934 221125_WJC_METTL3_EV_vs_WT_F10.16575.16575.4 2.88E-06 15/150 K.KPLPDHVSIVEPKDEILPTTPISEQK.G "sp|P23396|RS3_HUMAN,tr|H0YEU2|H0YEU2_HUMAN,tr|E9PSF4|E9PSF4_HUMAN,tr|E9PL09|E9PL09_HUMAN,tr|E9PPU1|E9PPU1_HUMAN" 5 2909.575 0.77 146059 16575 4 2909.596733 728.401 40S ribosomal protein S3 OS=Homo sapiens OX=9606 GN=RPS3 PE=1 SV=2 4.9 2981.4 - 150401 - - - 7.4729 - 3.019 0.52 - 121.6 1 2 1 0.0217 26 0 0 0 8.49E+07 1.10E+08 - - - 4.0946 0.9903 221125_WJC_METTL3_EV_vs_WT_F10.16582.16582.3 0.00312 Jul-48 R.LVHPGVAEVVFVK[136.11].K "sp|Q9BY77|PDIP3_HUMAN,tr|F6VRR5|F6VRR5_HUMAN" 2 1400.8271 1.53 146062 16582 3 1400.834104 467.9497 Polymerase delta-interacting protein 3 OS=Homo sapiens OX=9606 GN=POLDIP3 PE=1 SV=2 6.75 2982.4 - 61708.5 - - - 4.9842 - 1.405 0.379 - 63.5 1 2 0 0.007 13 0 0 0 2.43E+06 1.58E+06 - - - 3.6855 1 221125_WJC_METTL3_EV_vs_WT_F10.16597.16597.4 1.62E-07 17/150 R.SPSPC[160.03]WGPNPVPYPGDLGC[160.03]HESSPHR.L sp|Q5T749|KPRP_HUMAN 1 2886.2602 290.74 146070 16597 4 2886.276197 722.5723 Keratinocyte proline-rich protein OS=Homo sapiens OX=9606 GN=KPRP PE=1 SV=1 5.94 2984.4 - 144122 - - - 5.5314 - 2.71 0.667 - 107.6 1 2 0 0.016 26 0 0 0 1.14E+08 3.91E+05 - - - 5.3416 0.9913 221125_WJC_METTL3_EV_vs_WT_F10.16611.16611.3 0.000207 7/132 R.SDSPVPTAPTSGGPK[136.11]PSTASAVPELATDPELEK[136.11]K[136.11].L "sp|Q86U44|MTA70_HUMAN,tr|B4E349|B4E349_HUMAN,tr|F5H6D8|F5H6D8_HUMAN,tr|B4DTN4|B4DTN4_HUMAN" 4 3384.7363 0.001 146075 16611 3 3385.748466 1129.2527 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 4.51 2986.5 - 43183.2 - - - 299.0499 - 1.794 0.498 - 24.3 1 2 0 1.0122 34 0 0 0 0.00E+00 1.66E+06 - - - 5.1564 0.9989 221125_WJC_METTL3_EV_vs_WT_F10.16619.16619.4 1.78E-05 10/174 K.TGQEYK[136.11]PGNPPAEIGQNISSNSSASILESK[136.11].S "sp|P07814|SYEP_HUMAN,tr|V9GYZ6|V9GYZ6_HUMAN" 2 3118.539 0.9 146080 16619 4 3118.55711 780.642 Bifunctional glutamate\proline--tRNA ligase OS=Homo sapiens OX=9606 GN=EPRS1 PE=1 SV=5 4.78 2987.6 - 80755.2 - - - 5.8226 - 2.045 0.486 - 48.5 1 2 0 0.0182 30 0 0 0 1.81E+07 2.01E+07 - - - 3.67 1 221125_WJC_METTL3_EV_vs_WT_F10.16624.16624.4 1.22E-08 22/168 K.SQWVAPSSVVLHDEGQNEEDVEKEEETER.M "sp|Q9Y2L1|RRP44_HUMAN,tr|F2Z2C0|F2Z2C0_HUMAN,tr|G3V1J5|G3V1J5_HUMAN" 3 3354.5124 2.1 146083 16624 4 3354.534292 839.6354 Exosome complex exonuclease RRP44 OS=Homo sapiens OX=9606 GN=DIS3 PE=1 SV=2 4.04 2988.3 - 345126 - - - 6.5255 - 4.1 0.644 - 261.6 1 2 1 0.0219 29 0 0 0 1.30E+07 6.20E+06 - - - 5.2602 0.9976 221125_WJC_METTL3_EV_vs_WT_F10.16631.16631.4 2.06E-06 11/174 K.TGQEYKPGNPPAEIGQNISSNSSASILESK.S "sp|P07814|SYEP_HUMAN,tr|V9GYZ6|V9GYZ6_HUMAN" 2 3102.5106 0.9 146087 16631 4 3102.537653 776.6349 Bifunctional glutamate\proline--tRNA ligase OS=Homo sapiens OX=9606 GN=EPRS1 PE=1 SV=5 4.78 2989.3 - 120718 - - - 8.7352 - 2.515 0.53 - 47.3 1 2 0 0.0271 30 0 0 0 1.81E+07 2.02E+07 - - - 4.1138 0.981 221125_WJC_METTL3_EV_vs_WT_F10.16638.16638.3 0.00182 Jun-52 R.IVATKPLYVALAQR.K "sp|Q9H361|PABP3_HUMAN,sp|P11940|PABP1_HUMAN,tr|A0A7I2YQE4|A0A7I2YQE4_HUMAN,tr|A0A7I2V649|A0A7I2V649_HUMAN,tr|H0YB86|H0YB86_HUMAN,tr|H0YAR2|H0YAR2_HUMAN,tr|E7ERJ7|E7ERJ7_HUMAN,tr|A0A7I2YQ88|A0A7I2YQ88_HUMAN,tr|A0A087WTT1|A0A087WTT1_HUMAN,tr|A0A7I2YQ90|A0A7I2YQ90_HUMAN,tr|A0A7I2V4N4|A0A7I2V4N4_HUMAN,tr|E7EQV3|E7EQV3_HUMAN" 12 1541.9293 1.33 146091 16638 3 1541.938433 514.9837 Polyadenylate-binding protein 3 OS=Homo sapiens OX=9606 GN=PABPC3 PE=1 SV=2 9.99 2990.2 - 90799.7 - - - 5.8913 - 1.423 0.386 - 40 2 2 0 0.0091 14 0 0 0 2.00E+06 1.51E+06 - - - 3.6392 0.9975 221125_WJC_METTL3_EV_vs_WT_F10.16647.16647.2 1.74E-07 28-Nov K.NQVALNPQNTVFDAK[136.11].R "sp|P0DMV8|HS71A_HUMAN,sp|P0DMV9|HS71B_HUMAN,tr|A0A0G2JIW1|A0A0G2JIW1_HUMAN" 3 1665.8566 0.03 146094 16647 2 1665.864934 833.9356 Heat shock 70 kDa protein 1A OS=Homo sapiens OX=9606 GN=HSPA1A PE=1 SV=1 5.84 2991.6 - 82319.2 - - - 5.0124 - 2.094 0.53 - 310.3 1 2 0 0.0083 15 0 0 0 6.33E+05 2.01E+07 - - - 4.77 0.9943 221125_WJC_METTL3_EV_vs_WT_F10.16649.16649.4 0.000121 11/168 K.SQWVAPSSVVLHDEGQNEEDVEK[136.11]EEETER[166.11].M "sp|Q9Y2L1|RRP44_HUMAN,tr|F2Z2C0|F2Z2C0_HUMAN,tr|G3V1J5|G3V1J5_HUMAN" 3 3372.5349 2.1 146095 16649 4 3372.549375 844.141 Exosome complex exonuclease RRP44 OS=Homo sapiens OX=9606 GN=DIS3 PE=1 SV=2 4.04 2991.9 - 256247 - - - 4.3003 - 2.436 0.388 - 50.9 1 2 1 0.0145 29 0 0 0 1.30E+07 6.20E+06 - - - 2.8735 0.9996 221125_WJC_METTL3_EV_vs_WT_F10.16653.16653.4 0.00029 7/162 R.HVNGQDQIVPGLYAC[160.03]GEAAC[160.03]ASVHGANR[166.11].L "sp|P31040|SDHA_HUMAN,tr|A0A087X1I3|A0A087X1I3_HUMAN,tr|D6RFM5|D6RFM5_HUMAN" 3 2960.3645 0.92 146097 16653 4 2960.377253 741.0984 "Succinate dehydrogenase [ubiquinone] flavoprotein subunit, mitochondrial OS=Homo sapiens OX=9606 GN=SDHA PE=1 SV=2" 5.99 2992.3 - 98020 - - - 4.2988 - 1.911 0.492 - 20.3 1 2 0 0.0127 28 0 0 0 1.59E+07 1.73E+07 - - - 3.7059 0.9995 221125_WJC_METTL3_EV_vs_WT_F10.16656.16656.4 1.47E-06 11/120 K.KSESEVEEAAAIIAQRPDNPR.E "sp|Q16643|DREB_HUMAN,tr|D6R9Q9|D6R9Q9_HUMAN,tr|D6R9W4|D6R9W4_HUMAN" 3 2309.1612 0.83 146099 16656 4 2309.172509 578.2976 Drebrin OS=Homo sapiens OX=9606 GN=DBN1 PE=1 SV=4 4.59 2992.7 - 122105 - - - 4.9182 - 2.324 0.497 - 101.9 1 2 0 0.0114 21 0 0 0 4.15E+06 5.00E+06 - - - 3.8276 0.9999 221125_WJC_METTL3_EV_vs_WT_F10.16668.16668.4 3.45E-07 8/162 R.HVNGQDQIVPGLYAC[160.03]GEAAC[160.03]ASVHGANR.L "sp|P31040|SDHA_HUMAN,tr|A0A087X1I3|A0A087X1I3_HUMAN,tr|D6RFM5|D6RFM5_HUMAN" 3 2950.3563 0.93 146103 16668 4 2950.365098 738.5963 "Succinate dehydrogenase [ubiquinone] flavoprotein subunit, mitochondrial OS=Homo sapiens OX=9606 GN=SDHA PE=1 SV=2" 5.99 2994.4 - 95844.2 - - - 2.9966 - 2.265 0.579 - 21.3 1 2 0 0.0088 28 0 0 0 1.54E+07 1.66E+07 - - - 4.517 0.9908 221125_WJC_METTL3_EV_vs_WT_F10.16673.16673.4 0.00138 9/120 K.QEILENKDVVVQHVHFDGLGR.T sp|Q9Y512|SAM50_HUMAN 1 2431.2608 2.97 146105 16673 4 2431.27128 608.8225 Sorting and assembly machinery component 50 homolog OS=Homo sapiens OX=9606 GN=SAMM50 PE=1 SV=3 5.31 2995.1 - 108747 - - - 4.3076 - 1.88 0.367 - 45.2 1 2 1 0.0105 21 0 0 0 3.70E+06 1.24E+06 - - - 2.6262 0.978 221125_WJC_METTL3_EV_vs_WT_F10.16675.16675.4 0.00744 11/138 K.QREEYQPATPGLGMFVEVK[136.11]DPEDK[136.11].V sp|Q9BVK6|TMED9_HUMAN 1 2778.3505 - 146106 16675 4 2778.333403 695.5949 Transmembrane emp24 domain-containing protein 9 OS=Homo sapiens OX=9606 GN=TMED9 PE=1 SV=2 4.36 2995.5 - 524201 - - - -6.1702 - 2.459 0.382 - 53.6 1 2 2 -0.0171 24 0 0 0 - - - - - 2.835 0.99 221125_WJC_METTL3_EV_vs_WT_F10.16684.16684.3 0.076 Oct-56 R.ETNLDSLPLVDTHSK.R sp|P08670|VIME_HUMAN 1 1667.8366 4.56 146111 16684 3 1667.844688 556.9528 Vimentin OS=Homo sapiens OX=9606 GN=VIM PE=1 SV=4 4.54 2996.8 - 312048 - - - 4.8314 - 2.018 0.288 - 134.7 1 2 0 0.0081 15 0 0 0 3.90E+07 8.56E+06 - - - 3.5807 0.9998 221125_WJC_METTL3_EV_vs_WT_F10.16706.16706.4 2.52E-08 10/180 K.IGVFNTSGGSHSGQNSGTLNGGDVINLRPNK.Q sp|Q9ULC3|RAB23_HUMAN 1 3096.5337 0.68 146120 16706 4 3096.547856 775.1407 Ras-related protein Rab-23 OS=Homo sapiens OX=9606 GN=RAB23 PE=1 SV=1 8.75 3000 - 161381 - - - 4.5758 - 3.138 0.554 - 43.2 1 2 0 0.0142 31 0 0 0 1.39E+07 2.04E+07 - - - 4.3917 0.9999 221125_WJC_METTL3_EV_vs_WT_F10.16743.16743.4 6.95E-09 17/114 K.R[166.11]GLLQDDAHPTLVTYADHSK[136.11].L "sp|Q86U44|MTA70_HUMAN,tr|F5H6D8|F5H6D8_HUMAN,tr|H0YFV6|H0YFV6_HUMAN,tr|B4DTN4|B4DTN4_HUMAN" 4 2254.1461 0.01 146138 16743 4 2254.154955 564.5438 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 5.99 3005.4 - 168396 - - - 3.9217 - 2.749 0.572 - 252.1 1 2 0 0.0088 20 0 0 0 2.06E+05 1.50E+07 - - - 4.5403 1 221125_WJC_METTL3_EV_vs_WT_F10.16756.16756.3 2.15E-17 31/116 K.TGQEYK[136.11]PGNPPAEIGQNISSNSSASILESK[136.11].S "sp|P07814|SYEP_HUMAN,tr|V9GYZ6|V9GYZ6_HUMAN" 2 3118.539 1.01 146142 16756 3 3118.543726 1040.5203 Bifunctional glutamate\proline--tRNA ligase OS=Homo sapiens OX=9606 GN=EPRS1 PE=1 SV=5 4.78 3007.4 - 2.35E+06 - - - 1.5308 - 5.781 0.735 - 811.4 1 2 0 0.0048 30 0 0 0 1.19E+08 1.18E+08 - - - 10.7698 0.9998 221125_WJC_METTL3_EV_vs_WT_F10.16757.16757.4 1.23E-05 13/120 K.NQEHHNALGVILQVSSNSTSR.V sp|Q15477|SKIV2_HUMAN 1 2290.1414 0.93 146143 16757 4 2290.149648 573.5426 Helicase SKI2W OS=Homo sapiens OX=9606 GN=SKIV2L PE=1 SV=3 6.92 3007.5 - 180452 - - - 3.5928 - 2.526 0.506 - 117.8 1 2 0 0.0082 21 0 0 0 6.09E+06 6.55E+06 - - - 3.9343 1 221125_WJC_METTL3_EV_vs_WT_F10.16769.16769.3 7.36E-15 30/116 K.TGQEYKPGNPPAEIGQNISSNSSASILESK.S "sp|P07814|SYEP_HUMAN,tr|V9GYZ6|V9GYZ6_HUMAN" 2 3102.5106 1 146150 16769 3 3102.514707 1035.1775 Bifunctional glutamate\proline--tRNA ligase OS=Homo sapiens OX=9606 GN=EPRS1 PE=1 SV=5 4.78 3009.1 - 2.29E+06 - - - 1.3392 - 5.177 0.736 - 736.5 1 2 0 0.0042 30 0 0 0 1.30E+08 1.30E+08 - - - 10.5273 1 221125_WJC_METTL3_EV_vs_WT_F10.16778.16778.4 2.08E-10 30/150 K.K[136.11]PLPDHVSIVEPK[136.11]DEILPTTPISEQK[136.11].G "sp|P23396|RS3_HUMAN,tr|H0YEU2|H0YEU2_HUMAN,tr|E9PSF4|E9PSF4_HUMAN,tr|E9PL09|E9PL09_HUMAN,tr|E9PPU1|E9PPU1_HUMAN" 5 2933.6176 0.77 146155 16778 4 2933.619569 734.4117 40S ribosomal protein S3 OS=Homo sapiens OX=9606 GN=RPS3 PE=1 SV=2 4.9 3010.3 - 812550 - - - 0.6746 - 4.744 0.631 - 616.9 1 2 1 0.002 26 0 0 0 8.49E+07 1.10E+08 - - - 5.2088 0.9955 221125_WJC_METTL3_EV_vs_WT_F10.16788.16788.3 0.174 Jun-36 R.K[136.11]QDSGHLDLR[166.11].N "sp|Q86U44|MTA70_HUMAN,tr|B4E349|B4E349_HUMAN,tr|F5H6D8|F5H6D8_HUMAN,tr|B4DTN4|B4DTN4_HUMAN" 4 1185.6221 0.001 146162 16788 3 1185.620983 396.2146 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 6.75 3011.7 - 103745 - - - -0.9463 - 1.226 0.284 - 60 1 2 0 -0.0011 10 0 0 0 0.00E+00 4.69E+06 - - - 2.3011 1 221125_WJC_METTL3_EV_vs_WT_F10.16790.16790.4 5.32E-13 30/150 K.KPLPDHVSIVEPKDEILPTTPISEQK.G "sp|P23396|RS3_HUMAN,tr|H0YEU2|H0YEU2_HUMAN,tr|E9PSF4|E9PSF4_HUMAN,tr|E9PL09|E9PL09_HUMAN,tr|E9PPU1|E9PPU1_HUMAN" 5 2909.575 0.77 146163 16790 4 2909.585845 728.401 40S ribosomal protein S3 OS=Homo sapiens OX=9606 GN=RPS3 PE=1 SV=2 4.9 3011.9 - 683373 - - - 3.7308 - 4.897 0.687 - 658 1 2 1 0.0109 26 0 0 0 8.49E+07 1.10E+08 - - - 5.7037 1 221125_WJC_METTL3_EV_vs_WT_F10.16826.16826.3 7.61E-18 21/92 R.HQDDEPVNSQYFQTTSTNLSLSNK[136.11].L "sp|Q6NSI4|RADX_HUMAN,tr|B1AQ74|B1AQ74_HUMAN" 2 2760.2718 1.9 146180 16826 3 2760.265354 921.0979 RPA-related protein RADX OS=Homo sapiens OX=9606 GN=RADX PE=1 SV=2 4.54 3016.7 - 323202 - - - -2.3469 - 4.214 0.796 - 466.3 1 2 0 -0.0065 24 0 0 0 1.70E+07 8.95E+06 - - - 10.7537 1 221125_WJC_METTL3_EV_vs_WT_F10.16845.16845.4 1.83E-14 20/156 K.TQTVC[160.03]NFTDGALVQHQEWDGKESTITR.K "sp|Q01469|FABP5_HUMAN,sp|A8MUU1|FB5L3_HUMAN,tr|I6L8B7|I6L8B7_HUMAN" 3 3120.4571 888.12 146189 16845 4 3120.456763 781.1215 Fatty acid-binding protein 5 OS=Homo sapiens OX=9606 GN=FABP5 PE=1 SV=3 4.75 3019.1 - 706566 - - - -0.1006 - 4.296 0.704 - 206.9 1 2 1 -0.0003 27 0 0 0 8.66E+07 9.75E+04 - - - 5.8096 1 221125_WJC_METTL3_EV_vs_WT_F10.16847.16847.3 2.56E-14 20/104 R.DEQAFPALSSSSVNQSASQSSNPC[160.03]VQR.K sp|Q01804|OTUD4_HUMAN 1 2880.2944 2.12 146191 16847 3 2880.295823 961.1054 OTU domain-containing protein 4 OS=Homo sapiens OX=9606 GN=OTUD4 PE=1 SV=4 4.37 3019.3 - 678373 - - - 0.4843 - 3.964 0.753 - 358.4 1 2 0 0.0014 27 0 0 0 4.81E+07 2.27E+07 - - - 10.1034 1 221125_WJC_METTL3_EV_vs_WT_F10.16856.16856.3 2.43E-09 15/104 R.DEQAFPALSSSSVNQSASQSSNPC[160.03]VQR[166.11].K sp|Q01804|OTUD4_HUMAN 1 2890.3027 2.12 146194 16856 3 2890.296602 964.4415 OTU domain-containing protein 4 OS=Homo sapiens OX=9606 GN=OTUD4 PE=1 SV=4 4.37 3020.6 - 345297 - - - -2.1091 - 2.986 0.681 - 194.9 1 2 0 -0.0061 27 0 0 0 4.79E+07 2.26E+07 - - - 8.6475 0.9811 221125_WJC_METTL3_EV_vs_WT_F10.16864.16864.2 2.70E-05 Oct-54 R.SDSPVPTAPTSGGPK[136.11]PSTASAVPELATD.P "sp|Q86U44|MTA70_HUMAN,tr|B4E349|B4E349_HUMAN,tr|F5H6D8|F5H6D8_HUMAN,tr|B4DTN4|B4DTN4_HUMAN" 4 2644.2959 0.001 146196 16864 2 2644.289807 1323.1552 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 4.27 3021.8 - 652058 - - - -2.3121 - 1.953 0.57 - 102.6 1 1 0 -0.0061 28 0 0 0 0.00E+00 2.95E+07 - - - 4.8948 0.9999 221125_WJC_METTL3_EV_vs_WT_F10.16882.16882.4 1.17E-07 22/198 R.SDSPVPTAPTSGGPK[136.11]PSTASAVPELATDPELEK[136.11]K[136.11].L "sp|Q86U44|MTA70_HUMAN,tr|B4E349|B4E349_HUMAN,tr|F5H6D8|F5H6D8_HUMAN,tr|B4DTN4|B4DTN4_HUMAN" 4 3384.7363 0 146203 16882 4 3384.727769 847.1913 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 4.51 3024.2 - 3.13E+06 - - - -2.5089 - 3.356 0.463 - 186.2 1 2 0 -0.0085 34 0 0 0 1.03E+06 2.31E+08 - - - 3.6147 1 221125_WJC_METTL3_EV_vs_WT_F10.16903.16903.4 7.34E-10 24/144 R.SLNNFC[160.03]SQIGDDRPISYC[160.03]HFSPNSK.M sp|O43172|PRP4_HUMAN 1 2942.3076 4.4 146211 16903 4 2942.297444 736.5842 U4\U6 small nuclear ribonucleoprotein Prp4 OS=Homo sapiens OX=9606 GN=PRPF4 PE=1 SV=2 6.46 3027 - 1.38E+06 - - - -3.4436 - 4.316 0.632 - 348.3 1 2 0 -0.0101 25 0 0 0 4.44E+07 1.01E+07 - - - 5.1893 0.9999 221125_WJC_METTL3_EV_vs_WT_F10.16934.16934.4 7.09E-11 21/132 K.VKADRDESSPYAAMLAAQDVAQR.C "sp|P62263|RS14_HUMAN,tr|A0A2R8Y811|A0A2R8Y811_HUMAN,tr|E5RH77|E5RH77_HUMAN" 3 2491.2125 1.87 146220 16934 4 2491.210018 623.8104 40S ribosomal protein S14 OS=Homo sapiens OX=9606 GN=RPS14 PE=1 SV=3 4.68 3031.1 - 1.30E+06 - - - -1.0108 - 3.692 0.539 - 298.5 1 2 2 -0.0025 23 0 0 0 5.95E+07 3.18E+07 - - - 4.3399 0.9971 221125_WJC_METTL3_EV_vs_WT_F10.16967.16967.4 0.000276 Oct-72 K.LKDLFDYSPPLHK.N "sp|Q9NYF8|BCLF1_HUMAN,tr|E9PKI6|E9PKI6_HUMAN,tr|A0A1W2PQ43|A0A1W2PQ43_HUMAN,tr|E9PK91|E9PK91_HUMAN,tr|E9PK09|E9PK09_HUMAN,tr|E9PQN2|E9PQN2_HUMAN" 6 1571.8348 3.57 146234 16967 4 1571.834279 393.966 Bcl-2-associated transcription factor 1 OS=Homo sapiens OX=9606 GN=BCLAF1 PE=1 SV=2 6.75 3035.6 - 279817 - - - -0.3187 - 1.643 0.319 - 58.9 1 2 1 -0.0005 13 0 0 0 1.65E+07 4.64E+06 - - - 2.1865 0.9934 221125_WJC_METTL3_EV_vs_WT_F10.16974.16974.3 0.122 Jun-48 K.LKDLFDYSPPLHK.N "sp|Q9NYF8|BCLF1_HUMAN,tr|E9PKI6|E9PKI6_HUMAN,tr|A0A1W2PQ43|A0A1W2PQ43_HUMAN,tr|E9PK91|E9PK91_HUMAN,tr|E9PK09|E9PK09_HUMAN,tr|E9PQN2|E9PQN2_HUMAN" 6 1571.8348 7.65 146239 16974 3 1571.833519 524.9522 Bcl-2-associated transcription factor 1 OS=Homo sapiens OX=9606 GN=BCLAF1 PE=1 SV=2 6.75 3036.6 - 215317 - - - -0.8022 - 1.421 0.319 - 34 1 2 1 -0.0013 13 0 0 0 5.97E+06 7.80E+05 - - - 3.0488 0.7671 221125_WJC_METTL3_EV_vs_WT_F10.16977.16977.4 52.4 2/174 A.GGTGLSLGALVIVLASALLLLVLVLLVALR.A sp|P55291|CAD15_HUMAN 1 2926.8926 999 146240 16977 4 2927.902174 732.7304 Cadherin-15 OS=Homo sapiens OX=9606 GN=CDH15 PE=1 SV=1 9.75 3037 - 251018 - - - 344.9225 - 0.489 0.571 - 0.6 1 1 0 1.0096 30 0 0 0 1.10E+07 0.00E+00 - - - 3.6974 0.9998 221125_WJC_METTL3_EV_vs_WT_F10.16998.16998.3 0.000336 Dec-48 R.GYFEYIEENKYSR.A "sp|Q00839|HNRPU_HUMAN,tr|Q5RI18|Q5RI18_HUMAN,tr|A0A1W2PP35|A0A1W2PP35_HUMAN,tr|A0A1W2PPS1|A0A1W2PPS1_HUMAN,tr|A0A1W2PRI6|A0A1W2PRI6_HUMAN" 5 1696.7733 1.2 146249 16998 3 1696.776723 566.5984 Heterogeneous nuclear ribonucleoprotein U OS=Homo sapiens OX=9606 GN=HNRNPU PE=1 SV=6 4.79 3039.7 - 146207 - - - 2.0162 - 2.569 0.508 - 154.4 1 2 1 0.0034 13 0 0 0 9.82E+06 8.22E+06 - - - 6.7609 0.9991 221125_WJC_METTL3_EV_vs_WT_F10.17001.17001.3 0.00274 Aug-48 R.GYFEYIEENK[136.11]YSR[166.11].A "sp|Q00839|HNRPU_HUMAN,tr|Q5RI18|Q5RI18_HUMAN,tr|A0A1W2PP35|A0A1W2PP35_HUMAN,tr|A0A1W2PPS1|A0A1W2PPS1_HUMAN,tr|A0A1W2PRI6|A0A1W2PRI6_HUMAN" 5 1714.7958 1.2 146251 17001 3 1714.794939 572.6059 Heterogeneous nuclear ribonucleoprotein U OS=Homo sapiens OX=9606 GN=HNRNPU PE=1 SV=6 4.79 3040 - 248750 - - - -0.4858 - 1.982 0.377 - 53 1 2 1 -0.0008 13 0 0 0 9.82E+06 8.22E+06 - - - 4.5978 1 221125_WJC_METTL3_EV_vs_WT_F10.17004.17004.4 9.48E-06 20/198 R.TASTPTPPQTGGGLEPQANGETPQVAVIVR[166.11]PDDR[166.11].S "sp|Q04637|IF4G1_HUMAN,tr|C9J2Z7|C9J2Z7_HUMAN,tr|C9JWH7|C9JWH7_HUMAN,tr|E7EUU4|E7EUU4_HUMAN,tr|E9PGM1|E9PGM1_HUMAN,tr|C9J6B6|C9J6B6_HUMAN,tr|E7EX73|E7EX73_HUMAN,tr|C9JWW9|C9JWW9_HUMAN,tr|C9K073|C9K073_HUMAN,tr|C9JSU8|C9JSU8_HUMAN,tr|C9J556|C9J556_HUMAN,tr|A0A7I2Y1C3|A0A7I2Y1C3_HUMAN,tr|C9JF13|C9JF13_HUMAN" 13 3475.7446 1.06 146252 17004 4 3475.745251 869.9434 Eukaryotic translation initiation factor 4 gamma 1 OS=Homo sapiens OX=9606 GN=EIF4G1 PE=1 SV=4 4.32 3040.5 - 714061 - - - 0.1787 - 3.41 0.52 - 191.1 1 2 0 0.0006 34 0 0 0 5.69E+07 5.37E+07 - - - 4.1177 1 221125_WJC_METTL3_EV_vs_WT_F10.17012.17012.3 7.26E-06 Dec-80 K.C[160.03]QNEQLQTAVTQQVSQIQQHK.D sp|O60763|USO1_HUMAN 1 2495.2187 0.66 146256 17012 3 2495.223155 832.7468 General vesicular transport factor p115 OS=Homo sapiens OX=9606 GN=USO1 PE=1 SV=2 6.74 3041.5 - 154580 - - - 1.7918 - 2.561 0.583 - 137.8 1 2 0 0.0045 21 0 0 0 1.06E+07 1.62E+07 - - - 7.2932 1 221125_WJC_METTL3_EV_vs_WT_F10.17015.17015.3 5.00E-12 Dec-80 K.C[160.03]QNEQLQTAVTQQVSQIQQHK[136.11].D sp|O60763|USO1_HUMAN 1 2503.2329 0.65 146257 17015 3 2503.231393 835.4182 General vesicular transport factor p115 OS=Homo sapiens OX=9606 GN=USO1 PE=1 SV=2 6.74 3041.9 - 260377 - - - -0.5956 - 2.767 0.662 - 172.1 1 2 0 -0.0015 21 0 0 0 1.06E+07 1.64E+07 - - - 8.3603 0.9759 221125_WJC_METTL3_EV_vs_WT_F10.17032.17032.4 0.0195 Jul-96 R.EKDRDPEAQFEMPYVVR.L "sp|O14744|ANM5_HUMAN,tr|H0YJD3|H0YJD3_HUMAN,tr|H7BZ44|H7BZ44_HUMAN" 3 2107.9997 2.77 146263 17032 4 2107.99232 528.0072 Protein arginine N-methyltransferase 5 OS=Homo sapiens OX=9606 GN=PRMT5 PE=1 SV=4 4.51 3044.2 - 189730 - - - -3.4962 - 1.838 0.284 - 34.3 1 2 2 -0.0074 17 0 0 0 5.73E+06 2.07E+06 - - - 1.9072 0.9999 221125_WJC_METTL3_EV_vs_WT_F10.17047.17047.4 1.41E-05 Sep-90 K.YFLHDDR[166.11]DDGVDYWAK[136.11].R "sp|Q9NYF8|BCLF1_HUMAN,tr|H0YF14|H0YF14_HUMAN" 2 2031.9082 2.42 146269 17047 4 2031.907433 508.9843 Bcl-2-associated transcription factor 1 OS=Homo sapiens OX=9606 GN=BCLAF1 PE=1 SV=2 4.28 3046.3 - 226613 - - - -0.3657 - 1.884 0.542 - 58.7 1 2 1 -0.0007 16 0 0 0 1.87E+07 7.72E+06 - - - 4.1665 0.9998 221125_WJC_METTL3_EV_vs_WT_F10.17049.17049.4 0.000272 13/90 K.YFLHDDRDDGVDYWAK.R "sp|Q9NYF8|BCLF1_HUMAN,tr|H0YF14|H0YF14_HUMAN" 2 2013.8857 2.42 146271 17049 4 2013.883576 504.4787 Bcl-2-associated transcription factor 1 OS=Homo sapiens OX=9606 GN=BCLAF1 PE=1 SV=2 4.28 3046.5 - 439526 - - - -1.0577 - 2.223 0.464 - 99 1 2 1 -0.0021 16 0 0 0 1.88E+07 7.78E+06 - - - 3.5455 1 221125_WJC_METTL3_EV_vs_WT_F10.17050.17050.4 2.15E-09 14/84 K.HTTSIFDDFAHYEK[136.11]R[166.11].Q "sp|Q9BYJ9|YTHD1_HUMAN,sp|Q7Z739|YTHD3_HUMAN,tr|A0A087X0Q1|A0A087X0Q1_HUMAN,tr|A0A024R7W5|A0A024R7W5_HUMAN,tr|A0A087WY31|A0A087WY31_HUMAN" 5 1883.8921 1.29 146272 17050 4 1883.885778 471.9803 YTH domain-containing family protein 1 OS=Homo sapiens OX=9606 GN=YTHDF1 PE=1 SV=1 6 3046.7 - 261917 - - - -3.3728 - 3.076 0.622 - 285 1 2 0 -0.0064 15 0 0 0 1.54E+07 1.20E+07 - - - 5.0402 0.9999 221125_WJC_METTL3_EV_vs_WT_F10.17058.17058.3 7.17E-05 14/132 R.TASTPTPPQTGGGLEPQANGETPQVAVIVRPDDR.S "sp|Q04637|IF4G1_HUMAN,tr|C9J2Z7|C9J2Z7_HUMAN,tr|C9JWH7|C9JWH7_HUMAN,tr|E7EUU4|E7EUU4_HUMAN,tr|E9PGM1|E9PGM1_HUMAN,tr|C9J6B6|C9J6B6_HUMAN,tr|E7EX73|E7EX73_HUMAN,tr|C9JWW9|C9JWW9_HUMAN,tr|C9K073|C9K073_HUMAN,tr|C9JSU8|C9JSU8_HUMAN,tr|C9J556|C9J556_HUMAN,tr|A0A7I2Y1C3|A0A7I2Y1C3_HUMAN,tr|C9JF13|C9JF13_HUMAN" 13 3455.7281 1.94 146276 17058 3 3455.720221 1152.9166 Eukaryotic translation initiation factor 4 gamma 1 OS=Homo sapiens OX=9606 GN=EIF4G1 PE=1 SV=4 4.32 3047.8 - 642083 - - - -2.2771 - 2.079 0.498 - 48.9 1 2 0 -0.0079 34 0 0 0 2.01E+07 1.04E+07 - - - 5.7738 1 221125_WJC_METTL3_EV_vs_WT_F10.17059.17059.4 3.83E-08 15/84 K.HTTSIFDDFAHYEKR.Q "sp|Q9BYJ9|YTHD1_HUMAN,sp|Q7Z739|YTHD3_HUMAN,tr|A0A087X0Q1|A0A087X0Q1_HUMAN,tr|A0A024R7W5|A0A024R7W5_HUMAN,tr|A0A087WY31|A0A087WY31_HUMAN" 5 1865.8697 1.29 146277 17059 4 1865.870609 467.4747 YTH domain-containing family protein 1 OS=Homo sapiens OX=9606 GN=YTHDF1 PE=1 SV=1 6 3047.9 - 392290 - - - 0.5075 - 3.33 0.591 - 380.8 1 2 0 0.0009 15 0 0 0 1.54E+07 1.19E+07 - - - 4.8002 1 221125_WJC_METTL3_EV_vs_WT_F10.17064.17064.3 7.40E-07 20/84 K.TKEQVTNVGGAVVTGVTAVAQK.T "sp|P37840|SYUA_HUMAN,tr|A0A669KB41|A0A669KB41_HUMAN,tr|A0A669KBH5|A0A669KBH5_HUMAN,tr|H6UYS7|H6UYS7_HUMAN,tr|E7EPV7|E7EPV7_HUMAN" 5 2156.1801 1.66 146279 17064 3 2156.181424 719.734 Alpha-synuclein OS=Homo sapiens OX=9606 GN=SNCA PE=1 SV=1 8.26 3048.6 - 448066 - - - 0.6154 - 3.523 0.597 - 472.9 1 2 1 0.0013 22 0 0 0 3.42E+07 2.06E+07 - - - 8.1812 0.9989 221125_WJC_METTL3_EV_vs_WT_F10.17071.17071.3 0.00399 9/132 R.TASTPTPPQTGGGLEPQANGETPQVAVIVR[166.11]PDDR[166.11].S "sp|Q04637|IF4G1_HUMAN,tr|C9J2Z7|C9J2Z7_HUMAN,tr|C9JWH7|C9JWH7_HUMAN,tr|E7EUU4|E7EUU4_HUMAN,tr|E9PGM1|E9PGM1_HUMAN,tr|C9J6B6|C9J6B6_HUMAN,tr|E7EX73|E7EX73_HUMAN,tr|C9JWW9|C9JWW9_HUMAN,tr|C9K073|C9K073_HUMAN,tr|C9JSU8|C9JSU8_HUMAN,tr|C9J556|C9J556_HUMAN,tr|A0A7I2Y1C3|A0A7I2Y1C3_HUMAN,tr|C9JF13|C9JF13_HUMAN" 13 3475.7446 1.94 146283 17071 3 3475.736405 1159.5888 Eukaryotic translation initiation factor 4 gamma 1 OS=Homo sapiens OX=9606 GN=EIF4G1 PE=1 SV=4 4.32 3049.4 - 358071 - - - -2.3664 - 1.556 0.385 - 19.4 1 2 0 -0.0082 34 0 0 0 2.01E+07 1.04E+07 - - - 3.8472 0.9993 221125_WJC_METTL3_EV_vs_WT_F10.17072.17072.4 0.000694 11/150 R.NSQWVPTLPNSSHHLDAVPC[160.03]STTINR.N "sp|Q12824|SNF5_HUMAN,tr|A0A2R8Y5N5|A0A2R8Y5N5_HUMAN,tr|A0A2R8YEE8|A0A2R8YEE8_HUMAN,tr|C9JTA6|C9JTA6_HUMAN,tr|G5E975|G5E975_HUMAN,tr|A0A0G2JSE9|A0A0G2JSE9_HUMAN" 6 2930.4093 1.95 146284 17072 4 2930.404665 733.6096 SWI\SNF-related matrix-associated actin-dependent regulator of chromatin subfamily B member 1 OS=Homo sapiens OX=9606 GN=SMARCB1 PE=1 SV=2 6.91 3049.6 - 426831 - - - -1.595 - 2.349 0.32 - 53.9 1 2 0 -0.0047 26 0 0 0 1.38E+07 7.10E+06 - - - 2.2794 0.9996 221125_WJC_METTL3_EV_vs_WT_F10.17082.17082.2 0.00275 20-Aug K.DAVEDLESVGK.G sp|P81605|DCD_HUMAN 1 1160.5561 12.25 146287 17082 2 1160.557055 581.2853 Dermcidin OS=Homo sapiens OX=9606 GN=DCD PE=1 SV=2 3.92 3051.1 - 116414 - - - 0.8246 - 1.82 0.399 - 191 1 2 0 0.001 11 0 0 0 5.95E+06 4.86E+05 - - - 3.6077 1 221125_WJC_METTL3_EV_vs_WT_F10.17086.17086.3 2.10E-05 11/128 R.SDSPVPTAPTSGGPK[136.11]PSTASAVPELATDPELEK[136.11].K "sp|Q86U44|MTA70_HUMAN,tr|B4E349|B4E349_HUMAN,tr|F5H6D8|F5H6D8_HUMAN,tr|B4DTN4|B4DTN4_HUMAN" 4 3248.6271 0.02 146289 17086 3 3248.630289 1083.883 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 4.18 3051.6 - 263836 - - - 0.9823 - 2.4 0.563 - 62.7 1 2 0 0.0032 33 0 0 0 4.81E+05 3.13E+07 - - - 6.8301 1 221125_WJC_METTL3_EV_vs_WT_F10.17092.17092.4 1.49E-14 27/144 K.HSTPHAAFQPNSQIGEEMSQNSFIK[136.11].Q "sp|Q9UKV3|ACINU_HUMAN,tr|S4R3H4|S4R3H4_HUMAN,tr|E7EQT4|E7EQT4_HUMAN" 3 2792.3068 1.53 146292 17092 4 2792.30915 699.084 Apoptotic chromatin condensation inducer in the nucleus OS=Homo sapiens OX=9606 GN=ACIN1 PE=1 SV=2 6 3052.4 - 492340 - - - 0.8498 - 4.878 0.628 - 606.5 1 2 0 0.0024 25 0 0 0 1.41E+07 9.23E+06 - - - 5.1956 1 221125_WJC_METTL3_EV_vs_WT_F10.17102.17102.3 3.05E-06 14/72 R.HPHDIIDDINSGAVEC[160.03]PAS.- sp|P30050|RL12_HUMAN 1 2045.9113 - 146297 17102 3 2045.913111 682.9777 60S ribosomal protein L12 OS=Homo sapiens OX=9606 GN=RPL12 PE=1 SV=1 4.21 3053.7 - 552593 - - - 0.9003 - 2.882 0.538 - 231.5 1 2 0 0.0018 19 0 0 0 - - - - - 7.1381 0.9999 221125_WJC_METTL3_EV_vs_WT_F10.17103.17103.4 0.00346 8/150 R.NSQWVPTLPNSSHHLDAVPC[160.03]STTINR[166.11].N "sp|Q12824|SNF5_HUMAN,tr|A0A2R8Y5N5|A0A2R8Y5N5_HUMAN,tr|A0A2R8YEE8|A0A2R8YEE8_HUMAN,tr|C9JTA6|C9JTA6_HUMAN,tr|G5E975|G5E975_HUMAN,tr|A0A0G2JSE9|A0A0G2JSE9_HUMAN" 6 2940.4176 1.89 146298 17103 4 2940.418787 736.1117 SWI\SNF-related matrix-associated actin-dependent regulator of chromatin subfamily B member 1 OS=Homo sapiens OX=9606 GN=SMARCB1 PE=1 SV=2 6.91 3053.8 - 354007 - - - 0.4006 - 2.031 0.435 - 25.2 1 2 0 0.0012 26 0 0 0 1.23E+07 6.48E+06 - - - 3.2354 1 221125_WJC_METTL3_EV_vs_WT_F10.17114.17114.4 3.70E-06 18/96 K.HSQAVEELAEQLEQTK[136.11]R[166.11].V sp|P35579|MYH9_HUMAN 1 2013.0246 0.84 146303 17114 4 2013.022533 504.2634 Myosin-9 OS=Homo sapiens OX=9606 GN=MYH9 PE=1 SV=4 4.91 3055.3 - 200801 - - - -1.0278 - 3.494 0.567 - 275.3 1 2 0 -0.0021 17 0 0 0 5.50E+06 6.52E+06 - - - 4.595 1 221125_WJC_METTL3_EV_vs_WT_F10.17129.17129.3 7.86E-05 19/112 R.QSGQTDPLQK[136.11]EELQSGVDAANSAAQQYQR[166.11].R "sp|P46940|IQGA1_HUMAN,tr|A0A0J9YXZ5|A0A0J9YXZ5_HUMAN" 2 3164.5089 1.06 146310 17129 3 3164.505544 1055.8436 Ras GTPase-activating-like protein IQGAP1 OS=Homo sapiens OX=9606 GN=IQGAP1 PE=1 SV=1 4.32 3057.2 - 454299 - - - -1.0706 - 3.434 0.61 - 337.7 1 2 1 -0.0034 29 0 0 0 2.44E+07 2.31E+07 - - - 8.1783 1 221125_WJC_METTL3_EV_vs_WT_F10.17138.17138.3 7.35E-19 23/112 R.QSGQTDPLQKEELQSGVDAANSAAQQYQR.R "sp|P46940|IQGA1_HUMAN,tr|A0A0J9YXZ5|A0A0J9YXZ5_HUMAN" 2 3146.4865 1.06 146314 17138 3 3146.480002 1049.8361 Ras GTPase-activating-like protein IQGAP1 OS=Homo sapiens OX=9606 GN=IQGAP1 PE=1 SV=1 4.32 3058.4 - 498324 - - - -2.0531 - 4.554 0.762 - 628.8 1 2 1 -0.0065 29 0 0 0 2.44E+07 2.31E+07 - - - 10.5215 1 221125_WJC_METTL3_EV_vs_WT_F10.17147.17147.4 2.11E-06 21/198 R.SDSPVPTAPTSGGPK[136.11]PSTASAVPELATDPELEK[136.11]K[136.11].L "sp|Q86U44|MTA70_HUMAN,tr|B4E349|B4E349_HUMAN,tr|F5H6D8|F5H6D8_HUMAN,tr|B4DTN4|B4DTN4_HUMAN" 4 3384.7363 0 146318 17147 4 3384.734613 847.1913 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 4.51 3059.4 - 1.73E+06 - - - -0.4869 - 3.201 0.491 - 188.4 1 2 0 -0.0016 34 0 0 0 1.48E+05 1.13E+08 - - - 3.8462 0.8198 221125_WJC_METTL3_EV_vs_WT_F10.17176.17176.3 0.0863 Jun-44 D.GIHLLDPDVVAR[166.11].F sp|Q86U44|MTA70_HUMAN 1 1313.7331 0.26 146335 17176 3 1313.732581 438.9183 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 5.21 3063.3 - 71747.8 - - - -0.3989 - 1.444 0.291 - 56.1 1 1 0 -0.0005 12 0 0 0 5.61E+05 2.18E+06 - - - 2.8026 0.9991 221125_WJC_METTL3_EV_vs_WT_F10.17186.17186.4 1.21E-05 14/168 R.QSGQTDPLQKEELQSGVDAANSAAQQYQR.R "sp|P46940|IQGA1_HUMAN,tr|A0A0J9YXZ5|A0A0J9YXZ5_HUMAN" 2 3146.4865 3.33 146343 17186 4 3146.49081 787.6289 Ras GTPase-activating-like protein IQGAP1 OS=Homo sapiens OX=9606 GN=IQGAP1 PE=1 SV=1 4.32 3064.6 - 249646 - - - 1.3819 - 2.896 0.372 - 89.9 1 2 1 0.0043 29 0 0 0 1.06E+07 3.18E+06 - - - 2.7904 0.9913 221125_WJC_METTL3_EV_vs_WT_F10.17193.17193.2 0.103 14-Apr R.EFADFEYR.K "sp|Q8ND56|LS14A_HUMAN,tr|A0A140TA66|A0A140TA66_HUMAN,tr|A0A096LP11|A0A096LP11_HUMAN,tr|A0A0G2JQ95|A0A0G2JQ95_HUMAN" 4 1075.4611 1.04 146348 17193 2 1075.463431 538.7378 Protein LSM14 homolog A OS=Homo sapiens OX=9606 GN=LSM14A PE=1 SV=3 4.14 3065.5 - 93246.6 - - - 2.1907 - 0.914 0.356 - 56.2 1 2 0 0.0024 8 0 0 0 1.88E+06 1.82E+06 - - - 1.3985 1 221125_WJC_METTL3_EV_vs_WT_F10.17196.17196.4 6.86E-07 15/150 K.SQSEYK[136.11]PDTPQSGLEYSGIQELEDR[166.11]R[166.11].S sp|Q16513|PKN2_HUMAN 1 3039.4416 0.91 146349 17196 4 3039.443172 760.8677 Serine\threonine-protein kinase N2 OS=Homo sapiens OX=9606 GN=PKN2 PE=1 SV=1 4.36 3065.9 - 381350 - - - 0.5244 - 2.863 0.564 - 129.1 1 2 0 0.0016 26 0 0 0 1.70E+07 1.87E+07 - - - 4.4664 0.9993 221125_WJC_METTL3_EV_vs_WT_F10.17198.17198.2 0.0695 16-Aug R.VLDELTLAR.A "sp|Q04695|K1C17_HUMAN,sp|P02533|K1C14_HUMAN,sp|P08727|K1C19_HUMAN,sp|P08779|K1C16_HUMAN,sp|P19012|K1C15_HUMAN,tr|K7EPJ9|K7EPJ9_HUMAN,tr|C9JM50|C9JM50_HUMAN,tr|C9JTG5|C9JTG5_HUMAN,tr|F5GWP8|F5GWP8_HUMAN,tr|K7EMS3|K7EMS3_HUMAN,tr|A8MT21|A8MT21_HUMAN" 11 1028.5866 391.56 146350 17198 2 1028.588387 515.3006 "Keratin, type I cytoskeletal 17 OS=Homo sapiens OX=9606 GN=KRT17 PE=1 SV=2" 4.37 3066.1 - 221593 - - - 1.7276 - 1.842 0.343 - 223.6 1 2 0 0.0018 9 0 0 0 9.61E+06 2.45E+04 - - - 3.3411 1 221125_WJC_METTL3_EV_vs_WT_F10.17202.17202.4 1.48E-07 17/114 K.R[166.11]GLLQDDAHPTLVTYADHSK[136.11].L "sp|Q86U44|MTA70_HUMAN,tr|F5H6D8|F5H6D8_HUMAN,tr|H0YFV6|H0YFV6_HUMAN,tr|B4DTN4|B4DTN4_HUMAN" 4 2254.1461 0.01 146352 17202 4 2254.144786 564.5438 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 5.99 3066.6 - 200263 - - - -0.5896 - 2.983 0.513 - 177.3 1 2 0 -0.0013 20 0 0 0 1.16E+05 1.56E+07 - - - 4.0562 1 221125_WJC_METTL3_EV_vs_WT_F10.17204.17204.4 3.79E-06 14/150 K.SQSEYKPDTPQSGLEYSGIQELEDRR.S sp|Q16513|PKN2_HUMAN 1 3011.4108 0.91 146353 17204 4 3011.416415 753.86 Serine\threonine-protein kinase N2 OS=Homo sapiens OX=9606 GN=PKN2 PE=1 SV=1 4.36 3066.8 - 523798 - - - 1.852 - 2.64 0.571 - 102.6 1 2 0 0.0056 26 0 0 0 1.70E+07 1.86E+07 - - - 4.5007 0.9383 221125_WJC_METTL3_EV_vs_WT_F10.17220.17220.3 0.12 Jun-36 R.K[136.11]QDSGHLDLR[166.11].N "sp|Q86U44|MTA70_HUMAN,tr|B4E349|B4E349_HUMAN,tr|F5H6D8|F5H6D8_HUMAN,tr|B4DTN4|B4DTN4_HUMAN" 4 1185.6221 0.01 146360 17220 3 1185.61869 396.2146 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 6.75 3068.9 - 66320.8 - - - -2.8803 - 1.17 0.218 - 60.9 1 2 0 -0.0034 10 0 0 0 1.54E+04 3.00E+06 - - - 1.4281 0.9987 221125_WJC_METTL3_EV_vs_WT_F10.17239.17239.2 0.0433 16-Jul R.LFEGNALLR.R "sp|P46781|RS9_HUMAN,tr|C9JM19|C9JM19_HUMAN,tr|B5MCT8|B5MCT8_HUMAN" 3 1031.5764 46.54 146365 17239 2 1031.576951 516.7955 40S ribosomal protein S9 OS=Homo sapiens OX=9606 GN=RPS9 PE=1 SV=3 6 3071.7 - 224653 - - - 0.5535 - 1.285 0.335 - 145.8 1 2 0 0.0006 9 0 0 0 1.36E+07 2.93E+05 - - - 2.2406 1 221125_WJC_METTL3_EV_vs_WT_F10.17252.17252.3 1.83E-12 23/136 K.QGSGSSQPMEVQEGYGFGSGDDPYSSAEPHVSGVK[136.11].R sp|Q13263|TIF1B_HUMAN 1 3564.5467 0.68 146368 17252 3 3564.539935 1189.1895 Transcription intermediary factor 1-beta OS=Homo sapiens OX=9606 GN=TRIM28 PE=1 SV=5 4.17 3073.7 - 724002 - - - -1.8939 - 3.593 0.779 - 249.5 1 2 0 -0.0068 35 0 0 0 2.55E+07 3.77E+07 - - - 10.1657 1 221125_WJC_METTL3_EV_vs_WT_F10.17258.17258.3 8.17E-16 21/136 K.QGSGSSQPMEVQEGYGFGSGDDPYSSAEPHVSGVK.R sp|Q13263|TIF1B_HUMAN 1 3556.5325 0.68 146370 17258 3 3556.525318 1186.5181 Transcription intermediary factor 1-beta OS=Homo sapiens OX=9606 GN=TRIM28 PE=1 SV=5 4.17 3074.4 - 1.08E+06 - - - -2.0154 - 4.005 0.814 - 238.2 1 2 0 -0.0072 35 0 0 0 2.55E+07 3.77E+07 - - - 10.8055 0.9999 221125_WJC_METTL3_EV_vs_WT_F10.17273.17273.4 0.00102 17/138 K.DTSSEEVNLSHIVPC[160.03]EPVPEEKPK.E sp|Q8N0X7|SPART_HUMAN 1 2719.3011 1.5 146372 17273 4 2719.294775 680.8325 Spartin OS=Homo sapiens OX=9606 GN=SPART PE=1 SV=1 4.41 3076.8 - 1.22E+06 - - - -2.3175 - 2.386 0.461 - 113.4 1 2 0 -0.0063 24 0 0 0 7.29E+07 4.86E+07 - - - 3.5159 0.9999 221125_WJC_METTL3_EV_vs_WT_F10.17281.17281.4 1.27E-05 16/138 K.DTSSEEVNLSHIVPC[160.03]EPVPEEK[136.11]PK[136.11].E sp|Q8N0X7|SPART_HUMAN 1 2735.3295 1.48 146375 17281 4 2735.329085 684.8396 Spartin OS=Homo sapiens OX=9606 GN=SPART PE=1 SV=1 4.41 3077.8 - 621109 - - - -0.1433 - 2.443 0.438 - 108.1 1 2 0 -0.0004 24 0 0 0 5.74E+07 3.88E+07 - - - 3.3249 0.9999 221125_WJC_METTL3_EV_vs_WT_F10.17285.17285.4 7.95E-09 16/120 R.DSFDDR[166.11]GPSLNPVLDYDHGSR[166.11].S "sp|P43243|MATR3_HUMAN,tr|A8MXP9|A8MXP9_HUMAN,tr|D6R991|D6R991_HUMAN,tr|A0A0R4J2E8|A0A0R4J2E8_HUMAN,tr|D6REM6|D6REM6_HUMAN" 5 2381.0787 1.31 146376 17285 4 2381.082086 596.277 Matrin-3 OS=Homo sapiens OX=9606 GN=MATR3 PE=1 SV=2 4.28 3078.4 - 439422 - - - 1.4195 - 3.223 0.568 - 168.6 1 2 1 0.0034 21 0 0 0 1.03E+08 7.88E+07 - - - 4.5559 0.9999 221125_WJC_METTL3_EV_vs_WT_F10.17298.17298.4 3.63E-06 18/120 R.DSFDDRGPSLNPVLDYDHGSR.S "sp|P43243|MATR3_HUMAN,tr|A8MXP9|A8MXP9_HUMAN,tr|D6R991|D6R991_HUMAN,tr|A0A0R4J2E8|A0A0R4J2E8_HUMAN,tr|D6REM6|D6REM6_HUMAN" 5 2361.0622 1.31 146380 17298 4 2361.062388 591.2728 Matrin-3 OS=Homo sapiens OX=9606 GN=MATR3 PE=1 SV=2 4.28 3080.4 - 1.77E+06 - - - 0.094 - 3.17 0.514 - 221 1 2 1 0.0002 21 0 0 0 1.04E+08 7.94E+07 - - - 4.0813 0.9526 221125_WJC_METTL3_EV_vs_WT_F10.17303.17303.4 7.53E-08 16/186 R.AEQDSTTVAAFASSLVSGLNSSASEPAK[136.11]EPAK[136.11].K "sp|Q86U44|MTA70_HUMAN,tr|F5H6D8|F5H6D8_HUMAN,tr|H0YFV6|H0YFV6_HUMAN,tr|B4DTN4|B4DTN4_HUMAN" 4 3165.5648 0.04 146382 17303 4 3166.555736 792.3985 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 4.41 3081.1 - 550849 - - - 313.026 - 3.262 0.478 - 99.1 1 2 1 0.9909 32 0 0 0 4.38E+05 1.08E+07 - - - 3.469 1 221125_WJC_METTL3_EV_vs_WT_F10.17304.17304.4 4.03E-05 12/102 K.EKPKPTPDYLMQLMNDKK.L sp|Q96PU8|QKI_HUMAN 1 2175.1068 2.02 146383 17304 4 2175.10534 544.784 Protein quaking OS=Homo sapiens OX=9606 GN=QKI PE=1 SV=1 8.47 3081.2 - 468346 - - - -0.6699 - 2.418 0.479 - 100.6 1 2 0 -0.0015 18 0 0 0 6.47E+07 3.21E+07 - - - 3.6973 1 221125_WJC_METTL3_EV_vs_WT_F10.17310.17310.3 2.26E-07 18/80 R.DSFDDR[166.11]GPSLNPVLDYDHGSR[166.11].S "sp|P43243|MATR3_HUMAN,tr|A8MXP9|A8MXP9_HUMAN,tr|D6R991|D6R991_HUMAN,tr|A0A0R4J2E8|A0A0R4J2E8_HUMAN,tr|D6REM6|D6REM6_HUMAN" 5 2381.0787 1.22 146387 17310 3 2381.077357 794.7002 Matrin-3 OS=Homo sapiens OX=9606 GN=MATR3 PE=1 SV=2 4.28 3082 - 504169 - - - -0.5665 - 3.309 0.648 - 320.8 1 2 1 -0.0014 21 0 0 0 1.89E+07 1.55E+07 - - - 8.6331 0.999 221125_WJC_METTL3_EV_vs_WT_F10.17318.17318.3 0.000179 Sep-44 R.YLYTLVITDKEK.A "sp|P63173|RL38_HUMAN,tr|J3KT73|J3KT73_HUMAN,tr|J3QL01|J3QL01_HUMAN" 3 1484.8126 0.99 146391 17318 3 1484.810474 495.9448 60S ribosomal protein L38 OS=Homo sapiens OX=9606 GN=RPL38 PE=1 SV=2 6.07 3083 - 269868 - - - -1.4635 - 1.767 0.412 - 63.8 1 2 1 -0.0022 12 0 0 0 6.14E+06 6.20E+06 - - - 4.7108 0.9994 221125_WJC_METTL3_EV_vs_WT_F10.17319.17319.3 0.00013 Oct-44 R.YLYTLVITDK[136.11]EK[136.11].A "sp|P63173|RL38_HUMAN,tr|J3KT73|J3KT73_HUMAN,tr|J3QL01|J3QL01_HUMAN" 3 1500.841 0.99 146392 17319 3 1500.840833 501.2876 60S ribosomal protein L38 OS=Homo sapiens OX=9606 GN=RPL38 PE=1 SV=2 6.07 3083.2 - 287932 - - - -0.1426 - 1.809 0.432 - 89.3 1 2 1 -0.0002 12 0 0 0 6.14E+06 6.20E+06 - - - 4.9994 0.9707 221125_WJC_METTL3_EV_vs_WT_F10.17332.17332.4 0.0551 7/150 R.QKDNLELPSAEHQAIESSQASVETWK.Y "sp|Q96DF8|ESS2_HUMAN,tr|F8WEF8|F8WEF8_HUMAN" 2 2924.4152 1.94 146402 17332 4 2924.421133 732.1111 Splicing factor ESS-2 homolog OS=Homo sapiens OX=9606 GN=ESS2 PE=1 SV=1 4.57 3084.8 - 240540 - - - 2.0305 - 1.674 0.236 - 24.9 1 2 1 0.0059 26 0 0 0 6.92E+06 3.58E+06 - - - 1.441 1 221125_WJC_METTL3_EV_vs_WT_F10.17337.17337.4 6.66E-18 31/198 R.TERPVNSAALSPNYDHVVLGGGQEAMDVTTTSTR.L "sp|Q13347|EIF3I_HUMAN,tr|A0A7I2YQT9|A0A7I2YQT9_HUMAN,tr|A0A7I2V613|A0A7I2V613_HUMAN,tr|A0A7I2V3N2|A0A7I2V3N2_HUMAN,tr|A0A7I2YQU2|A0A7I2YQU2_HUMAN,tr|A0A7I2YQI6|A0A7I2YQI6_HUMAN,tr|A0A7I2YQF8|A0A7I2YQF8_HUMAN,tr|Q5TFK1|Q5TFK1_HUMAN,tr|A0A7I2V3U3|A0A7I2V3U3_HUMAN,tr|A0A7I2V607|A0A7I2V607_HUMAN,tr|A0A7I2V640|A0A7I2V640_HUMAN,tr|A0A7P0MRT9|A0A7P0MRT9_HUMAN,tr|A0A7I2V5V8|A0A7I2V5V8_HUMAN,tr|A0A7I2V2M3|A0A7I2V2M3_HUMAN,tr|A0A7I2V4C2|A0A7I2V4C2_HUMAN,tr|A0A7I2YQI2|A0A7I2YQI2_HUMAN,tr|A0A7I2YQC8|A0A7I2YQC8_HUMAN,tr|A0A7I2V685|A0A7I2V685_HUMAN" 18 3572.7165 1.16 146405 17337 4 3572.723326 894.1864 Eukaryotic translation initiation factor 3 subunit I OS=Homo sapiens OX=9606 GN=EIF3I PE=1 SV=1 4.75 3085.6 - 876044 - - - 1.8997 - 6.012 0.707 - 551.1 1 2 0 0.0068 34 0 0 0 2.00E+07 1.72E+07 - - - 5.9128 0.9858 221125_WJC_METTL3_EV_vs_WT_F10.17339.17339.4 0.00573 8/150 R.QK[136.11]DNLELPSAEHQAIESSQASVETWK[136.11].Y "sp|Q96DF8|ESS2_HUMAN,tr|F8WEF8|F8WEF8_HUMAN" 2 2940.4436 2.03 146407 17339 4 2940.454874 736.1182 Splicing factor ESS-2 homolog OS=Homo sapiens OX=9606 GN=ESS2 PE=1 SV=1 4.57 3085.8 - 148124 - - - 3.8358 - 1.665 0.33 - 30.1 1 2 1 0.0113 26 0 0 0 7.25E+06 3.58E+06 - - - 2.256 0.9627 221125_WJC_METTL3_EV_vs_WT_F10.17340.17340.3 3.35E-06 Nov-52 W.ELISNASDALDKIR.Y "sp|Q58FF8|H90B2_HUMAN,sp|P08238|HS90B_HUMAN,sp|Q58FF6|H90B4_HUMAN,sp|Q58FF7|H90B3_HUMAN,sp|P14625|ENPL_HUMAN,tr|A0A7P0T917|A0A7P0T917_HUMAN,tr|A0A7P0Z405|A0A7P0Z405_HUMAN,tr|A0A7P0T823|A0A7P0T823_HUMAN,tr|A0A7P0TAE1|A0A7P0TAE1_HUMAN,tr|H0YIV0|H0YIV0_HUMAN,tr|A0A7P0T8R3|A0A7P0T8R3_HUMAN,tr|A0A7P0T885|A0A7P0T885_HUMAN,tr|A0A7P0TAY2|A0A7P0TAY2_HUMAN,tr|A0A087WT78|A0A087WT78_HUMAN,tr|F8W026|F8W026_HUMAN,tr|A0A7P0TBC2|A0A7P0TBC2_HUMAN,tr|A0A7P0TAT8|A0A7P0TAT8_HUMAN" 17 1543.8206 22.65 146408 17340 3 1543.824548 515.6141 Putative heat shock protein HSP 90-beta 2 OS=Homo sapiens OX=9606 GN=HSP90AB2P PE=1 SV=2 4.56 3085.9 - 83413.8 - - - 2.5664 - 2.43 0.51 - 182.6 1 1 1 0.004 14 0 0 0 2.24E+06 9.89E+04 - - - 6.5845 1 221125_WJC_METTL3_EV_vs_WT_F10.17368.17368.2 1.45E-09 14/34 K.PSTASAVPELATDPELEK[136.11].K "sp|Q86U44|MTA70_HUMAN,tr|B4E349|B4E349_HUMAN,tr|F5H6D8|F5H6D8_HUMAN,tr|H0YFV6|H0YFV6_HUMAN,tr|B4DTN4|B4DTN4_HUMAN" 5 1861.94 0.001 146425 17368 2 1861.946232 931.9773 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 4 3089.6 - 116522 - - - 3.3261 - 2.689 0.633 - 386.7 1 1 0 0.0062 18 0 0 0 0.00E+00 5.36E+06 - - - 6.1463 0.9999 221125_WJC_METTL3_EV_vs_WT_F10.17369.17369.4 1.73E-05 13/144 R.SGNTDKPRPPPLPSEPPPPLPPLPK.- sp|O60563|CCNT1_HUMAN 1 2624.4326 1.75 146426 17369 4 2624.440989 657.1154 Cyclin-T1 OS=Homo sapiens OX=9606 GN=CCNT1 PE=1 SV=1 8.31 3089.7 - 123164 - - - 3.1877 - 2.602 0.557 - 86.2 1 2 0 0.0084 25 0 0 0 9.98E+06 5.71E+06 - - - 4.376 0.9999 221125_WJC_METTL3_EV_vs_WT_F10.17372.17372.4 3.01E-07 13/132 K.ASHHIYPYSSSQDDEEWLRPVMR.K sp|Q92922|SMRC1_HUMAN 1 2802.282 0.89 146427 17372 4 2802.292773 701.5778 SWI\SNF complex subunit SMARCC1 OS=Homo sapiens OX=9606 GN=SMARCC1 PE=1 SV=3 5.31 3090.1 - 256183 - - - 3.8397 - 2.925 0.581 - 117 1 2 0 0.0108 23 0 0 0 8.66E+06 9.72E+06 - - - 4.6278 1 221125_WJC_METTL3_EV_vs_WT_F10.17373.17373.4 3.24E-07 13/132 K.DGSGDSHPDFPEDADIDLKDVDK.L sp|Q08752|PPID_HUMAN 1 2486.0721 2.01 146428 17373 4 2486.081104 622.5253 Peptidyl-prolyl cis-trans isomerase D OS=Homo sapiens OX=9606 GN=PPID PE=1 SV=3 3.86 3090.3 - 188527 - - - 3.6129 - 2.661 0.634 - 76 1 2 1 0.009 23 0 0 0 1.18E+07 5.85E+06 - - - 5.0589 0.9999 221125_WJC_METTL3_EV_vs_WT_F10.17375.17375.4 3.27E-06 13/144 R.SGNTDK[136.11]PR[166.11]PPPLPSEPPPPLPPLPK[136.11].- sp|O60563|CCNT1_HUMAN 1 2650.4693 2.19 146430 17375 4 2650.478903 663.6246 Cyclin-T1 OS=Homo sapiens OX=9606 GN=CCNT1 PE=1 SV=1 8.31 3090.5 - 94784.1 - - - 3.6258 - 2.806 0.608 - 108.7 1 2 0 0.0096 25 0 0 0 4.72E+06 2.15E+06 - - - 4.8436 0.9446 221125_WJC_METTL3_EV_vs_WT_F10.17393.17393.4 0.0258 9/150 R.HNLITEMVALNPDFK[136.11]PPADYK[136.11]PPATR.V "sp|Q15637|SF01_HUMAN,tr|A0A7P0T9U7|A0A7P0T9U7_HUMAN" 2 2950.5346 - 146440 17393 4 2950.510173 738.6409 Splicing factor 1 OS=Homo sapiens OX=9606 GN=SF1 PE=1 SV=4 6.75 3093.1 - 302447 - - - -8.2785 - 1.893 0.328 - 27.9 1 2 0 -0.0244 26 0 0 0 - - - - - 2.2754 0.9876 221125_WJC_METTL3_EV_vs_WT_F10.17394.17394.4 0.0283 10/108 K.LAAAILGGVDQIHIKPGAK.V "sp|P22087|FBRL_HUMAN,tr|M0R299|M0R299_HUMAN,tr|M0R0P1|M0R0P1_HUMAN,tr|M0R1H0|M0R1H0_HUMAN,tr|M0QXL5|M0QXL5_HUMAN,tr|M0R2Q4|M0R2Q4_HUMAN,tr|M0R2B0|M0R2B0_HUMAN,tr|M0R2U2|M0R2U2_HUMAN" 8 1871.0993 0.86 146441 17394 4 1871.107783 468.7821 rRNA 2'-O-methyltransferase fibrillarin OS=Homo sapiens OX=9606 GN=FBL PE=1 SV=2 8.6 3093.2 - 72589 - - - 4.5508 - 1.815 0.29 - 97.4 1 2 0 0.0085 19 0 0 0 1.20E+06 1.41E+06 - - - 1.9494 1 221125_WJC_METTL3_EV_vs_WT_F10.17395.17395.4 1.07E-05 9/132 K.ASHHIYPYSSSQDDEEWLR[166.11]PVMR[166.11].K sp|Q92922|SMRC1_HUMAN 1 2822.2986 1.31 146442 17395 4 2822.299418 706.5819 SWI\SNF complex subunit SMARCC1 OS=Homo sapiens OX=9606 GN=SMARCC1 PE=1 SV=3 5.31 3093.3 - 201599 - - - 0.3065 - 2.391 0.534 - 41.3 1 2 0 0.0009 23 0 0 0 8.18E+06 6.26E+06 - - - 4.1561 0.8862 221125_WJC_METTL3_EV_vs_WT_F10.17396.17396.4 0.487 5/114 R.VANYC[160.03]STHLLEHITTNEDFR.A "sp|O75688|PPM1B_HUMAN,tr|B8ZZF0|B8ZZF0_HUMAN,tr|A0A3B3IS24|A0A3B3IS24_HUMAN,tr|C9JIR6|C9JIR6_HUMAN" 4 2419.1227 0.27 146443 17396 4 2419.133571 605.7879 Protein phosphatase 1B OS=Homo sapiens OX=9606 GN=PPM1B PE=1 SV=1 5.27 3093.4 - 130408 - - - 4.5107 - 1.162 0.206 - 16.9 1 2 0 0.0109 20 0 0 0 5.13E+06 1.91E+07 - - - 1.0662 0.994 221125_WJC_METTL3_EV_vs_WT_F10.17408.17408.4 9.00E-06 16/114 R.TSQNSELNNMQDLVEDYKKK.Y sp|P35908|K22E_HUMAN 1 2383.1326 147.82 146450 17408 4 2383.147047 596.7904 "Keratin, type II cytoskeletal 2 epidermal OS=Homo sapiens OX=9606 GN=KRT2 PE=1 SV=2" 4.78 3095.2 - 610375 - - - 6.0815 - 3.227 0.456 - 226.5 1 2 1 0.0145 20 0 0 0 1.61E+08 1.09E+06 - - - 3.5827 0.9877 221125_WJC_METTL3_EV_vs_WT_F10.17409.17409.4 6.99E-06 14/150 R.NALTALFTSSGRPPSQPNTQDKTPSK.V "sp|Q9ULV3|CIZ1_HUMAN,tr|Q5SYW2|Q5SYW2_HUMAN,tr|F5H2X7|F5H2X7_HUMAN,tr|H0Y5D5|H0Y5D5_HUMAN,tr|A0A494C0L7|A0A494C0L7_HUMAN,tr|Q9BTG3|Q9BTG3_HUMAN" 6 2742.3937 3.08 146451 17409 4 2742.410943 686.6057 Cip1-interacting zinc finger protein OS=Homo sapiens OX=9606 GN=CIZ1 PE=1 SV=2 9.99 3095.3 - 365826 - - - 6.2978 - 2.619 0.423 - 112.5 1 2 1 0.0173 26 0 0 0 4.58E+08 1.49E+08 - - - 3.2067 0.9993 221125_WJC_METTL3_EV_vs_WT_F10.17415.17415.3 1.10E-08 Dec-76 R.TSQNSELNNMQDLVEDYKKK.Y sp|P35908|K22E_HUMAN 1 2383.1326 999 146455 17415 3 2383.143815 795.3848 "Keratin, type II cytoskeletal 2 epidermal OS=Homo sapiens OX=9606 GN=KRT2 PE=1 SV=2" 4.78 3096.1 - 173796 - - - 4.7253 - 2.747 0.63 - 254.4 1 2 1 0.0113 20 0 0 0 2.47E+07 0.00E+00 - - - 8.0123 0.9995 221125_WJC_METTL3_EV_vs_WT_F10.17436.17436.3 1.96E-05 Sep-56 K.AAVEWFDGK[136.11]DFQGSK[136.11].L "sp|Q01844|EWS_HUMAN,tr|B0QYK0|B0QYK0_HUMAN,tr|H7BY36|H7BY36_HUMAN,tr|A0A0D9SFL3|A0A0D9SFL3_HUMAN,tr|C9JGE3|C9JGE3_HUMAN" 5 1699.8177 1.7 146465 17436 3 1699.813845 567.6132 RNA-binding protein EWS OS=Homo sapiens OX=9606 GN=EWSR1 PE=1 SV=1 4.56 3099 - 78708.8 - - - -2.2597 - 2.142 0.484 - 83.3 1 2 1 -0.0038 15 0 0 0 5.05E+06 2.97E+06 - - - 5.9227 0.99 221125_WJC_METTL3_EV_vs_WT_F10.17456.17456.3 3.57E-06 Nov-88 Y.ETQITQIEHEVSSSGQEVQSSAK.E "sp|P35527|K1C9_HUMAN,tr|K7EQQ3|K7EQQ3_HUMAN" 2 2501.1882 272.08 146479 17456 3 2501.180995 834.7367 "Keratin, type I cytoskeletal 9 OS=Homo sapiens OX=9606 GN=KRT9 PE=1 SV=3" 4.48 3101.8 - 275783 - - - -2.8626 - 2.666 0.515 - 69.9 1 1 0 -0.0072 23 0 0 0 2.93E+07 1.08E+05 - - - 6.5801 0.9999 221125_WJC_METTL3_EV_vs_WT_F10.17498.17498.4 3.92E-06 17/198 R.SDSPVPTAPTSGGPK[136.11]PSTASAVPELATDPELEK[136.11]K[136.11].L "sp|Q86U44|MTA70_HUMAN,tr|B4E349|B4E349_HUMAN,tr|F5H6D8|F5H6D8_HUMAN,tr|B4DTN4|B4DTN4_HUMAN" 4 3384.7363 0.01 146497 17498 4 3384.727718 847.1913 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 4.51 3107.1 - 2.43E+06 - - - -2.524 - 3.089 0.464 - 101 1 2 0 -0.0085 34 0 0 0 7.02E+05 1.39E+08 - - - 3.5986 0.9999 221125_WJC_METTL3_EV_vs_WT_F10.17521.17521.3 1.05E-07 18/100 R.NALTALFTSSGRPPSQPNTQDKTPSK.V "sp|Q9ULV3|CIZ1_HUMAN,tr|Q5SYW2|Q5SYW2_HUMAN,tr|F5H2X7|F5H2X7_HUMAN,tr|H0Y5D5|H0Y5D5_HUMAN,tr|A0A494C0L7|A0A494C0L7_HUMAN,tr|Q9BTG3|Q9BTG3_HUMAN" 6 2742.3937 3.98 146507 17521 3 2742.391642 915.1385 Cip1-interacting zinc finger protein OS=Homo sapiens OX=9606 GN=CIZ1 PE=1 SV=2 9.99 3110.1 - 778484 - - - -0.7402 - 3.322 0.575 - 226.1 1 2 1 -0.002 26 0 0 0 7.99E+07 2.01E+07 - - - 7.7122 0.9996 221125_WJC_METTL3_EV_vs_WT_F10.17538.17538.3 3.38E-09 14/56 K.HKELAPYDENWFYTR.A "sp|P39019|RS19_HUMAN,tr|M0R140|M0R140_HUMAN,tr|M0R2L9|M0R2L9_HUMAN,tr|M0QYF7|M0QYF7_HUMAN" 4 1967.9166 1 146510 17538 3 1967.90835 656.9795 40S ribosomal protein S19 OS=Homo sapiens OX=9606 GN=RPS19 PE=1 SV=2 5.45 3112.6 - 407550 - - - -4.1983 - 2.968 0.627 - 333 1 2 1 -0.0083 15 0 0 0 1.30E+07 1.30E+07 - - - 8.3668 0.9998 221125_WJC_METTL3_EV_vs_WT_F10.17540.17540.3 6.18E-09 14/56 K.HK[136.11]ELAPYDENWFYTR[166.11].A "sp|P39019|RS19_HUMAN,tr|M0R140|M0R140_HUMAN,tr|M0R2L9|M0R2L9_HUMAN,tr|M0QYF7|M0QYF7_HUMAN" 4 1985.9391 1 146511 17540 3 1985.933618 662.987 40S ribosomal protein S19 OS=Homo sapiens OX=9606 GN=RPS19 PE=1 SV=2 5.45 3112.8 - 616466 - - - -2.7513 - 2.778 0.564 - 234.3 1 2 1 -0.0055 15 0 0 0 1.30E+07 1.30E+07 - - - 7.4926 1 221125_WJC_METTL3_EV_vs_WT_F10.17543.17543.4 7.45E-15 30/186 R.QRHELLLGAGSGPGAGQQQATPGALLQAGPPR.C sp|Q96DI7|SNR40_HUMAN 1 3132.6541 1.99 146512 17543 4 3132.647911 784.1708 U5 small nuclear ribonucleoprotein 40 kDa protein OS=Homo sapiens OX=9606 GN=SNRNP40 PE=1 SV=1 9.61 3113.2 - 565802 - - - -1.9683 - 5.454 0.657 - 363.8 1 2 1 -0.0062 32 0 0 0 2.13E+07 1.07E+07 - - - 5.455 1 221125_WJC_METTL3_EV_vs_WT_F10.17544.17544.3 6.80E-05 17/100 R.NALTALFTSSGR[166.11]PPSQPNTQDK[136.11]TPSK[136.11].V "sp|Q9ULV3|CIZ1_HUMAN,tr|Q5SYW2|Q5SYW2_HUMAN,tr|F5H2X7|F5H2X7_HUMAN,tr|H0Y5D5|H0Y5D5_HUMAN,tr|A0A494C0L7|A0A494C0L7_HUMAN,tr|Q9BTG3|Q9BTG3_HUMAN" 6 2768.4303 3.93 146513 17544 3 2768.432342 923.8174 Cip1-interacting zinc finger protein OS=Homo sapiens OX=9606 GN=CIZ1 PE=1 SV=2 9.99 3113.4 - 448966 - - - 0.7224 - 3.613 0.595 - 269.9 1 2 1 0.002 26 0 0 0 7.86E+07 2.00E+07 - - - 8.1284 0.9998 221125_WJC_METTL3_EV_vs_WT_F10.17549.17549.4 2.59E-05 Dec-84 K.HK[136.11]ELAPYDENWFYTR[166.11].A "sp|P39019|RS19_HUMAN,tr|M0R140|M0R140_HUMAN,tr|M0R2L9|M0R2L9_HUMAN,tr|M0QYF7|M0QYF7_HUMAN" 4 1985.9391 1.05 146515 17549 4 1985.934316 497.492 40S ribosomal protein S19 OS=Homo sapiens OX=9606 GN=RPS19 PE=1 SV=2 5.45 3114 - 358081 - - - -2.3999 - 1.993 0.545 - 103.5 1 2 1 -0.0048 15 0 0 0 7.76E+06 7.41E+06 - - - 4.2151 0.9999 221125_WJC_METTL3_EV_vs_WT_F10.17551.17551.4 0.000116 Dec-84 K.HKELAPYDENWFYTR.A "sp|P39019|RS19_HUMAN,tr|M0R140|M0R140_HUMAN,tr|M0R2L9|M0R2L9_HUMAN,tr|M0QYF7|M0QYF7_HUMAN" 4 1967.9166 1.05 146516 17551 4 1967.920058 492.9864 40S ribosomal protein S19 OS=Homo sapiens OX=9606 GN=RPS19 PE=1 SV=2 5.45 3114.2 - 324520 - - - 1.7511 - 1.971 0.574 - 120 1 2 1 0.0034 15 0 0 0 7.76E+06 7.41E+06 - - - 4.4639 1 221125_WJC_METTL3_EV_vs_WT_F10.17565.17565.4 9.68E-10 27/186 R.QR[166.11]HELLLGAGSGPGAGQQQATPGALLQAGPPR[166.11].C sp|Q96DI7|SNR40_HUMAN 1 3152.6706 1.99 146524 17565 4 3152.675728 789.1749 U5 small nuclear ribonucleoprotein 40 kDa protein OS=Homo sapiens OX=9606 GN=SNRNP40 PE=1 SV=1 9.61 3116.1 - 325430 - - - 1.6212 - 4.891 0.678 - 344.7 1 2 1 0.0051 32 0 0 0 2.13E+07 1.07E+07 - - - 5.6052 0.9999 221125_WJC_METTL3_EV_vs_WT_F10.17582.17582.4 1.35E-05 15/120 R.K[136.11]HAASDVDLEIESLLNQQSTK[136.11].E "sp|Q86U44|MTA70_HUMAN,tr|F5H6D8|F5H6D8_HUMAN,tr|H0YFV6|H0YFV6_HUMAN,tr|B4DTN4|B4DTN4_HUMAN" 4 2341.2096 0.02 146536 17582 4 2341.209856 586.3097 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 4.75 3118.3 - 448910 - - - 0.1012 - 2.882 0.449 - 170.7 1 2 0 0.0002 21 0 0 0 1.86E+05 8.91E+06 - - - 3.484 1 221125_WJC_METTL3_EV_vs_WT_F10.17595.17595.4 7.39E-09 9/168 R.PQSC[160.03]HPC[160.03]C[160.03]YKPEAPGC[160.03]EAPDHLQGLGVPI.- sp|Q8N5Z5|KCD17_HUMAN 1 3273.4464 5.95 146544 17595 4 3273.458735 819.3689 BTB\POZ domain-containing protein KCTD17 OS=Homo sapiens OX=9606 GN=KCTD17 PE=1 SV=3 5.28 3120 - 243991 - - - 3.7697 - 2.106 0.675 - 18.5 1 1 0 0.0123 29 0 0 0 2.44E+07 4.11E+06 - - - 5.3273 0.9873 221125_WJC_METTL3_EV_vs_WT_F10.17605.17605.4 0.0946 8/126 K.QTQQRPTDMSALNNLFGPQKPK.V "sp|Q6P3W7|SCYL2_HUMAN,tr|A0A0U1RQQ9|A0A0U1RQQ9_HUMAN" 2 2498.27 1.98 146549 17605 4 2498.275463 625.5748 SCY1-like protein 2 OS=Homo sapiens OX=9606 GN=SCYL2 PE=1 SV=1 9.99 3121.3 - 158509 - - - 2.1903 - 1.532 0.221 - 32.3 1 2 0 0.0055 22 0 0 0 1.89E+08 9.52E+07 - - - 1.2876 0.9998 221125_WJC_METTL3_EV_vs_WT_F10.17611.17611.4 0.000793 9/126 K.QTQQR[166.11]PTDMSALNNLFGPQK[136.11]PK[136.11].V "sp|Q6P3W7|SCYL2_HUMAN,tr|A0A0U1RQQ9|A0A0U1RQQ9_HUMAN" 2 2524.3067 1.98 146555 17611 4 2524.309097 632.0839 SCY1-like protein 2 OS=Homo sapiens OX=9606 GN=SCYL2 PE=1 SV=1 9.99 3122.1 - 161045 - - - 0.965 - 1.779 0.395 - 46.5 1 2 0 0.0024 22 0 0 0 1.89E+08 9.52E+07 - - - 2.8519 0.9896 221125_WJC_METTL3_EV_vs_WT_F10.17621.17621.4 0.0491 Jun-84 R.GFC[160.03]FITFKEEEPVKK.L "sp|Q14103|HNRPD_HUMAN,tr|H0Y8G5|H0Y8G5_HUMAN,tr|H0YA96|H0YA96_HUMAN" 3 1857.9335 1.07 146561 17621 4 1857.939044 465.4907 Heterogeneous nuclear ribonucleoprotein D0 OS=Homo sapiens OX=9606 GN=HNRNPD PE=1 SV=1 6.22 3123.5 - 84626.9 - - - 2.9797 - 1.226 0.324 - 19.9 1 2 1 0.0055 15 0 0 0 2.12E+06 1.98E+06 - - - 2.1175 0.9998 221125_WJC_METTL3_EV_vs_WT_F10.17628.17628.3 0.00237 Jul-36 R.K[136.11]QDSGHLDLR[166.11].N "sp|Q86U44|MTA70_HUMAN,tr|B4E349|B4E349_HUMAN,tr|F5H6D8|F5H6D8_HUMAN,tr|B4DTN4|B4DTN4_HUMAN" 4 1185.6221 0.01 146565 17628 3 1185.623591 396.2146 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 6.75 3124.3 - 58046.7 - - - 1.2534 - 1.585 0.423 - 72.2 1 2 0 0.0015 10 0 0 0 4.82E+04 4.15E+06 - - - 4.6007 1 221125_WJC_METTL3_EV_vs_WT_F10.17633.17633.4 1.55E-08 13/114 K.DK[136.11]LESEMEDAYHEHQANLLR[166.11].Q "sp|P23246|SFPQ_HUMAN,tr|H0Y9K7|H0Y9K7_HUMAN" 2 2445.135 0.84 146568 17633 4 2445.140523 612.291 "Splicing factor, proline- and glutamine-rich OS=Homo sapiens OX=9606 GN=SFPQ PE=1 SV=2" 4.63 3125 - 117818 - - - 2.2759 - 2.648 0.639 - 129 1 2 1 0.0056 20 0 0 0 1.36E+07 1.62E+07 - - - 5.1119 0.9996 221125_WJC_METTL3_EV_vs_WT_F10.17636.17636.4 3.87E-06 11/192 K.TATQTGHTLLEDYQIVDNSQR[166.11]ENQEGAANVNVR[166.11].G sp|Q8N0X7|SPART_HUMAN 1 3690.7737 0.96 146569 17636 4 3690.785742 923.7007 Spartin OS=Homo sapiens OX=9606 GN=SPART PE=1 SV=1 4.5 3125.6 - 130170 - - - 3.2633 - 2.451 0.531 - 41.9 1 2 1 0.012 33 0 0 0 2.95E+06 3.08E+06 - - - 4.1135 0.9985 221125_WJC_METTL3_EV_vs_WT_F10.17638.17638.4 0.00593 12/138 R.KPRPVSQLVAQQVTQQFVPPTQSK.K sp|Q8IY57|YAF2_HUMAN 1 2690.4868 1.28 146571 17638 4 2690.496804 673.629 YY1-associated factor 2 OS=Homo sapiens OX=9606 GN=YAF2 PE=1 SV=3 11.17 3125.8 - 272719 - - - 3.7242 - 2.202 0.363 - 58.1 1 2 0 0.01 24 0 0 0 6.75E+06 5.29E+06 - - - 2.6361 1 221125_WJC_METTL3_EV_vs_WT_F10.17649.17649.4 9.33E-11 17/114 K.DKLESEMEDAYHEHQANLLR.Q "sp|P23246|SFPQ_HUMAN,tr|H0Y9K7|H0Y9K7_HUMAN" 2 2427.1125 0.84 146578 17649 4 2427.120372 607.7854 "Splicing factor, proline- and glutamine-rich OS=Homo sapiens OX=9606 GN=SFPQ PE=1 SV=2" 4.63 3127.3 - 321094 - - - 3.2483 - 3.655 0.675 - 288.7 1 2 1 0.0079 20 0 0 0 1.36E+07 1.62E+07 - - - 5.5323 1 221125_WJC_METTL3_EV_vs_WT_F10.17650.17650.4 6.30E-11 17/168 K.SLHHTQNDHFQNDGIVQPNPSVLIGNPIR.A "sp|P42694|HELZ_HUMAN,tr|J3QS41|J3QS41_HUMAN" 2 3246.6283 2.31 146579 17650 4 3246.637577 812.6643 Probable helicase with zinc finger domain OS=Homo sapiens OX=9606 GN=HELZ PE=1 SV=2 6.19 3127.4 - 267924 - - - 2.871 - 3.307 0.644 - 206.1 1 2 0 0.0093 29 0 0 0 2.36E+07 1.02E+07 - - - 5.1974 1 221125_WJC_METTL3_EV_vs_WT_F10.17663.17663.3 4.35E-11 16/84 K.QTQQR[166.11]PTDMSALNNLFGPQK[136.11]PK[136.11].V "sp|Q6P3W7|SCYL2_HUMAN,tr|A0A0U1RQQ9|A0A0U1RQQ9_HUMAN" 2 2524.3067 1.44 146586 17663 3 2524.312881 842.4428 SCY1-like protein 2 OS=Homo sapiens OX=9606 GN=SCYL2 PE=1 SV=1 9.99 3129.2 - 210357 - - - 2.464 - 3.167 0.598 - 243.6 1 2 0 0.0062 22 0 0 0 2.28E+07 1.58E+07 - - - 7.9384 0.9998 221125_WJC_METTL3_EV_vs_WT_F10.17665.17665.4 0.000126 13/144 R.SNSFNSTFEHHLPPSPLEHGTPFQR.E sp|Q5VT52|RPRD2_HUMAN 1 2862.3474 1.79 146588 17665 4 2862.35942 716.5941 Regulation of nuclear pre-mRNA domain-containing protein 2 OS=Homo sapiens OX=9606 GN=RPRD2 PE=1 SV=1 6.2 3129.4 - 182051 - - - 4.2028 - 2.391 0.513 - 75.8 1 2 0 0.012 25 0 0 0 8.09E+06 4.52E+06 - - - 3.9651 1 221125_WJC_METTL3_EV_vs_WT_F10.17676.17676.4 4.11E-10 13/150 K.HGEEFFPTSNSLLHGTHVPSTEEIDR.M sp|O95926|SYF2_HUMAN 1 2935.3737 1.57 146593 17676 4 2935.386731 734.8507 Pre-mRNA-splicing factor SYF2 OS=Homo sapiens OX=9606 GN=SYF2 PE=1 SV=1 4.89 3131.1 - 309787 - - - 4.4516 - 3.109 0.659 - 78.3 1 2 0 0.0131 26 0 0 0 1.87E+07 1.19E+07 - - - 5.3161 1 221125_WJC_METTL3_EV_vs_WT_F10.17688.17688.4 1.96E-09 11/168 K.SLHHTQNDHFQNDGIVQPNPSVLIGNPIR[166.11].A "sp|P42694|HELZ_HUMAN,tr|J3QS41|J3QS41_HUMAN" 2 3256.6365 2.39 146597 17688 4 3256.643196 815.1664 Probable helicase with zinc finger domain OS=Homo sapiens OX=9606 GN=HELZ PE=1 SV=2 6.19 3132.9 - 228853 - - - 2.0481 - 2.699 0.58 - 62.5 1 2 0 0.0067 29 0 0 0 2.21E+07 9.24E+06 - - - 4.5785 0.9999 221125_WJC_METTL3_EV_vs_WT_F10.17695.17695.4 0.000252 18/150 K.HGEEFFPTSNSLLHGTHVPSTEEIDR[166.11].M sp|O95926|SYF2_HUMAN 1 2945.3819 1.62 146599 17695 4 2945.390924 737.3528 Pre-mRNA-splicing factor SYF2 OS=Homo sapiens OX=9606 GN=SYF2 PE=1 SV=1 4.89 3134 - 346793 - - - 3.0522 - 3.211 0.48 - 118.6 1 2 0 0.009 26 0 0 0 1.93E+07 1.19E+07 - - - 3.7694 1 221125_WJC_METTL3_EV_vs_WT_F10.17710.17710.4 4.09E-06 12/138 R.K[136.11]SPTMEQAVQTASAHLPAPAAVGR[166.11].R sp|Q8ND56|LS14A_HUMAN 1 2435.271 1.65 146609 17710 4 2435.27315 609.825 Protein LSM14 homolog A OS=Homo sapiens OX=9606 GN=LSM14A PE=1 SV=3 8.75 3135.9 - 193789 - - - 0.8837 - 2.648 0.557 - 45.4 1 2 0 0.0022 24 0 0 0 1.51E+07 9.13E+06 - - - 4.3861 0.9997 221125_WJC_METTL3_EV_vs_WT_F10.17717.17717.4 0.000728 Jul-78 R.KVESLQEEIAFLKK.L "sp|P08670|VIME_HUMAN,tr|B0YJC5|B0YJC5_HUMAN,tr|B0YJC4|B0YJC4_HUMAN" 3 1660.94 1.67 146612 17717 4 1660.937313 416.2423 Vimentin OS=Homo sapiens OX=9606 GN=VIM PE=1 SV=4 6.23 3136.9 - 122933 - - - -1.6015 - 1.604 0.385 - 45.5 1 2 0 -0.0027 14 0 0 0 4.63E+06 2.76E+06 - - - 2.7483 1 221125_WJC_METTL3_EV_vs_WT_F10.17730.17730.3 0.000275 Dec-52 R.KVESLQEEIAFLKK.L "sp|P08670|VIME_HUMAN,tr|B0YJC5|B0YJC5_HUMAN,tr|B0YJC4|B0YJC4_HUMAN" 3 1660.94 0.03 146618 17730 3 1660.942637 554.6539 Vimentin OS=Homo sapiens OX=9606 GN=VIM PE=1 SV=4 6.23 3138.6 - 160596 - - - 1.6039 - 2.641 0.489 - 181.6 1 2 0 0.0027 14 0 0 0 1.02E+07 3.32E+08 - - - 6.572 0.9883 221125_WJC_METTL3_EV_vs_WT_F10.17736.17736.2 0.0322 20-May K.IGLFGGAGVGK.T "sp|P06576|ATPB_HUMAN,tr|F8W079|F8W079_HUMAN,tr|F8W0P7|F8W0P7_HUMAN,tr|H0YH81|H0YH81_HUMAN" 4 974.5549 16.22 146622 17736 2 974.557311 488.2847 "ATP synthase subunit beta, mitochondrial OS=Homo sapiens OX=9606 GN=ATP5F1B PE=1 SV=3" 8.75 3139.4 - 50543.3 - - - 2.4575 - 0.951 0.326 - 37.2 1 2 0 0.0024 11 0 0 0 1.54E+06 9.47E+04 - - - 1.3122 0.8055 221125_WJC_METTL3_EV_vs_WT_F10.17738.17738.4 2.71E-06 9/180 F.TAQVIILNHPGQISAGYAPVLDC[160.03]HTAHIAC[160.03]K[136.11].F "sp|P68104|EF1A1_HUMAN,tr|A0A7I2V659|A0A7I2V659_HUMAN,tr|A0A7I2V5N4|A0A7I2V5N4_HUMAN,tr|A0A087WVQ9|A0A087WVQ9_HUMAN,tr|A0A087WV01|A0A087WV01_HUMAN" 5 3362.7107 0.35 146624 17738 4 3362.742122 841.685 Elongation factor 1-alpha 1 OS=Homo sapiens OX=9606 GN=EEF1A1 PE=1 SV=1 6.73 3139.6 - 127205 - - - 9.3335 - 2.399 0.553 - 33.6 1 1 0 0.0314 31 0 0 0 1.81E+06 5.11E+06 - - - 4.2966 0.9955 221125_WJC_METTL3_EV_vs_WT_F10.17752.17752.4 1.31E-05 11/132 R.IVSR[166.11]PEELR[166.11]EDDVGTGAGLLEIK[136.11].K "sp|P49368|TCPG_HUMAN,tr|B4DUR8|B4DUR8_HUMAN" 2 2523.3539 0.46 146631 17752 4 2523.372191 631.8457 T-complex protein 1 subunit gamma OS=Homo sapiens OX=9606 GN=CCT3 PE=1 SV=4 4.36 3141.6 - 353990 - - - 7.2598 - 2.468 0.56 - 62.4 1 2 1 0.0183 23 0 0 0 3.35E+06 7.23E+06 - - - 4.3879 0.9756 221125_WJC_METTL3_EV_vs_WT_F10.17757.17757.4 0.001 11/150 R.NALTALFTSSGRPPSQPNTQDKTPSK.V "sp|Q9ULV3|CIZ1_HUMAN,tr|Q5SYW2|Q5SYW2_HUMAN,tr|F5H2X7|F5H2X7_HUMAN,tr|H0Y5D5|H0Y5D5_HUMAN,tr|A0A494C0L7|A0A494C0L7_HUMAN,tr|Q9BTG3|Q9BTG3_HUMAN" 6 2742.3937 3.8 146634 17757 4 2742.402302 686.6057 Cip1-interacting zinc finger protein OS=Homo sapiens OX=9606 GN=CIZ1 PE=1 SV=2 9.99 3142.3 - 205666 - - - 3.1469 - 1.945 0.273 - 63.3 1 2 1 0.0086 26 0 0 0 1.28E+07 3.37E+06 - - - 1.8096 1 221125_WJC_METTL3_EV_vs_WT_F10.17766.17766.4 2.90E-08 20/198 R.SDSPVPTAPTSGGPK[136.11]PSTASAVPELATDPELEK[136.11]K[136.11].L "sp|Q86U44|MTA70_HUMAN,tr|B4E349|B4E349_HUMAN,tr|F5H6D8|F5H6D8_HUMAN,tr|B4DTN4|B4DTN4_HUMAN" 4 3384.7363 0 146639 17766 4 3384.738776 847.1913 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 4.51 3143.5 - 867079 - - - 0.743 - 3.46 0.509 - 140.6 1 2 0 0.0025 34 0 0 0 3.51E+05 7.85E+07 - - - 4.0258 0.9999 221125_WJC_METTL3_EV_vs_WT_F10.17779.17779.4 3.48E-06 16/150 K.NDK[136.11]ESEAQISWFAPEDHGYGTEVSTK[136.11].N "sp|Q9H2U1|DHX36_HUMAN,tr|E7EWK3|E7EWK3_HUMAN" 2 2940.3385 0.8 146645 17779 4 2940.34108 736.0919 ATP-dependent DNA\RNA helicase DHX36 OS=Homo sapiens OX=9606 GN=DHX36 PE=1 SV=2 4.35 3145.2 - 297063 - - - 0.8907 - 3.045 0.557 - 100.2 1 2 1 0.0026 26 0 0 0 9.26E+06 1.15E+07 - - - 4.4246 0.9982 221125_WJC_METTL3_EV_vs_WT_F10.17844.17844.3 1.01E-06 10/128 R.SDSPVPTAPTSGGPK[136.11]PSTASAVPELATDPELEK[136.11].K "sp|Q86U44|MTA70_HUMAN,tr|B4E349|B4E349_HUMAN,tr|F5H6D8|F5H6D8_HUMAN,tr|B4DTN4|B4DTN4_HUMAN" 4 3248.6271 0.01 146674 17844 3 3248.605657 1083.883 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 4.18 3154.2 - 182478 - - - -6.6 - 2.255 0.523 - 49.7 1 2 0 -0.0214 33 0 0 0 1.46E+05 1.03E+07 - - - 6.2358 0.9999 221125_WJC_METTL3_EV_vs_WT_F10.17850.17850.3 0.000125 Sep-52 K.HTTSIFDDFSHYEK.R sp|Q9Y5A9|YTHD2_HUMAN 1 1725.7635 1.41 146677 17850 3 1725.768337 576.2618 YTH domain-containing family protein 2 OS=Homo sapiens OX=9606 GN=YTHDF2 PE=1 SV=2 5.21 3154.9 - 173110 - - - 2.8231 - 2.15 0.615 - 58.5 1 2 0 0.0049 14 0 0 0 4.01E+07 2.84E+07 - - - 7.4295 0.9723 221125_WJC_METTL3_EV_vs_WT_F10.17856.17856.2 0.000275 26-May K.HTDESLGDC[160.03]SFLNT.C "sp|Q86U44|MTA70_HUMAN,tr|H0YFV6|H0YFV6_HUMAN" 2 1594.657 - 146679 17856 2 1594.654886 798.3358 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 4.02 3155.8 - 191389 - - - -1.2949 - 1.342 0.493 - 44 1 1 0 -0.0021 14 0 0 0 - - - - - 3.4198 1 221125_WJC_METTL3_EV_vs_WT_F10.17857.17857.3 6.02E-08 13/52 K.HTTSIFDDFSHYEK[136.11].R sp|Q9Y5A9|YTHD2_HUMAN 1 1733.7777 1.41 146680 17857 3 1733.773227 578.9332 YTH domain-containing family protein 2 OS=Homo sapiens OX=9606 GN=YTHDF2 PE=1 SV=2 5.21 3155.9 - 399780 - - - -2.5597 - 2.904 0.647 - 155.5 1 2 0 -0.0044 14 0 0 0 4.00E+07 2.84E+07 - - - 8.5853 1 221125_WJC_METTL3_EV_vs_WT_F10.17866.17866.4 5.47E-09 Nov-78 K.HTTSIFDDFSHYEK.R sp|Q9Y5A9|YTHD2_HUMAN 1 1725.7635 1.57 146686 17866 4 1725.766715 432.4481 YTH domain-containing family protein 2 OS=Homo sapiens OX=9606 GN=YTHDF2 PE=1 SV=2 5.21 3157.2 - 147847 - - - 1.8832 - 2.406 0.644 - 56.1 1 2 0 0.0032 14 0 0 0 1.16E+07 7.36E+06 - - - 5.15 0.9999 221125_WJC_METTL3_EV_vs_WT_F10.17876.17876.4 0.00178 Oct-78 K.HTTSIFDDFSHYEK[136.11].R sp|Q9Y5A9|YTHD2_HUMAN 1 1733.7777 1.57 146690 17876 4 1733.776662 434.4517 YTH domain-containing family protein 2 OS=Homo sapiens OX=9606 GN=YTHDF2 PE=1 SV=2 5.21 3158.4 - 224038 - - - -0.5785 - 2.278 0.446 - 45.3 1 2 0 -0.001 14 0 0 0 1.16E+07 7.36E+06 - - - 3.4073 0.9999 221125_WJC_METTL3_EV_vs_WT_F10.17899.17899.4 2.64E-06 11/102 K.NVQDAIADAEQRGEHALK.D sp|P35908|K22E_HUMAN 1 1963.9712 1162.98 146700 17899 4 1963.970985 492.0001 "Keratin, type II cytoskeletal 2 epidermal OS=Homo sapiens OX=9606 GN=KRT2 PE=1 SV=2" 4.75 3161.4 - 167700 - - - -0.0927 - 2.084 0.516 - 103.8 1 2 1 -0.0002 18 0 0 0 3.63E+07 3.13E+04 - - - 3.9687 0.999 221125_WJC_METTL3_EV_vs_WT_F10.17904.17904.3 0.00302 Sep-68 K.NVQDAIADAEQRGEHALK.D sp|P35908|K22E_HUMAN 1 1963.9712 9.29 146703 17904 3 1963.969063 655.6643 "Keratin, type II cytoskeletal 2 epidermal OS=Homo sapiens OX=9606 GN=KRT2 PE=1 SV=2" 4.75 3162.1 - 131837 - - - -1.0713 - 1.95 0.387 - 65 1 2 1 -0.0021 18 0 0 0 1.88E+07 2.02E+06 - - - 4.517 0.9939 221125_WJC_METTL3_EV_vs_WT_F10.17906.17906.3 0.122 Jun-48 R.SIFDHIKLPQASK.S "sp|Q9NYF8|BCLF1_HUMAN,tr|E9PKI6|E9PKI6_HUMAN,tr|A0A1W2PQ43|A0A1W2PQ43_HUMAN,tr|E9PK91|E9PK91_HUMAN,tr|E9PJA7|E9PJA7_HUMAN,tr|E9PK09|E9PK09_HUMAN,tr|E9PQN2|E9PQN2_HUMAN" 7 1482.8195 3.9 146704 17906 3 1482.818994 495.2804 Bcl-2-associated transcription factor 1 OS=Homo sapiens OX=9606 GN=BCLAF1 PE=1 SV=2 8.33 3162.3 - 76641.5 - - - -0.317 - 1.155 0.375 - 33.5 1 2 1 -0.0005 13 0 0 0 4.58E+06 1.17E+06 - - - 3.1114 0.9999 221125_WJC_METTL3_EV_vs_WT_F10.17976.17976.4 3.60E-05 11/180 K.APDTNKEDDSKDNDSESDYMFMAPGAGAIPK.N "sp|O14654|IRS4_HUMAN,tr|A0A804CF45|A0A804CF45_HUMAN" 2 3315.4184 1.14 146731 17976 4 3315.416808 829.8619 Insulin receptor substrate 4 OS=Homo sapiens OX=9606 GN=IRS4 PE=1 SV=1 3.98 3171.9 - 282247 - - - -0.4702 - 2.38 0.623 - 49.6 1 2 2 -0.0016 31 0 0 0 7.28E+06 6.40E+06 - - - 4.9117 0.9995 221125_WJC_METTL3_EV_vs_WT_F10.17978.17978.4 0.00056 9/126 K.HFSIHPDTGVITTTTPFLDREK.C sp|Q08554|DSC1_HUMAN 1 2511.2758 15.96 146733 17978 4 2511.278923 628.8262 Desmocollin-1 OS=Homo sapiens OX=9606 GN=DSC1 PE=1 SV=2 6 3172.1 - 165131 - - - 1.2484 - 2.213 0.414 - 44.4 1 2 1 0.0031 22 0 0 0 2.81E+06 1.76E+05 - - - 3.0885 0.9999 221125_WJC_METTL3_EV_vs_WT_F10.17988.17988.4 2.01E-06 8/180 K.APDTNK[136.11]EDDSK[136.11]DNDSESDYMFMAPGAGAIPK[136.11].N "sp|O14654|IRS4_HUMAN,tr|A0A804CF45|A0A804CF45_HUMAN" 2 3339.461 1.14 146737 17988 4 3339.455303 835.8725 Insulin receptor substrate 4 OS=Homo sapiens OX=9606 GN=IRS4 PE=1 SV=1 3.98 3173.5 - 217647 - - - -1.6961 - 1.834 0.587 - 27.2 1 2 2 -0.0057 31 0 0 0 7.32E+06 6.40E+06 - - - 4.518 0.9995 221125_WJC_METTL3_EV_vs_WT_F10.18005.18005.3 9.55E-06 Nov-80 R.QVQSLTC[160.03]EVDALKGTNESLER.Q "sp|P08670|VIME_HUMAN,tr|B0YJC5|B0YJC5_HUMAN,tr|B0YJC4|B0YJC4_HUMAN" 3 2376.1591 1.86 146743 18005 3 2376.164055 793.0603 Vimentin OS=Homo sapiens OX=9606 GN=VIM PE=1 SV=4 4.41 3176 - 213850 - - - 2.0836 - 2.344 0.468 - 98 1 2 1 0.005 21 0 0 0 9.28E+06 4.99E+06 - - - 5.7987 1 221125_WJC_METTL3_EV_vs_WT_F10.18015.18015.3 1.40E-11 18/80 R.QVQSLTC[160.03]EVDALK[136.11]GTNESLER[166.11].Q "sp|P08670|VIME_HUMAN,tr|B0YJC5|B0YJC5_HUMAN,tr|B0YJC4|B0YJC4_HUMAN" 3 2394.1816 1.86 146749 18015 3 2394.186849 799.0678 Vimentin OS=Homo sapiens OX=9606 GN=VIM PE=1 SV=4 4.41 3177.2 - 239142 - - - 2.2033 - 3.578 0.641 - 293.1 1 2 1 0.0053 21 0 0 0 9.28E+06 4.99E+06 - - - 8.7413 0.9974 221125_WJC_METTL3_EV_vs_WT_F10.18021.18021.4 0.000933 7/114 K.TSAK[136.11]EEDAFHFVSYVPVNGR[166.11].L "sp|Q9Y5K5|UCHL5_HUMAN,tr|H0Y4E0|H0Y4E0_HUMAN,tr|Q5LJA9|Q5LJA9_HUMAN,tr|H0Y6Y4|H0Y6Y4_HUMAN,tr|Q5LJB0|Q5LJB0_HUMAN,tr|Q5LJA5|Q5LJA5_HUMAN" 6 2270.1087 0.99 146753 18021 4 2270.11485 568.5344 Ubiquitin carboxyl-terminal hydrolase isozyme L5 OS=Homo sapiens OX=9606 GN=UCHL5 PE=1 SV=3 5.41 3178 - 118638 - - - 2.7241 - 1.748 0.377 - 23 1 2 1 0.0062 20 0 0 0 4.98E+06 5.04E+06 - - - 2.6924 1 221125_WJC_METTL3_EV_vs_WT_F10.18045.18045.2 1.28E-08 Nov-36 K.GSLGGGFSSGGFSGGSFSR.G "sp|P13645|K1C10_HUMAN,tr|A0A1B0GVI3|A0A1B0GVI3_HUMAN" 2 1706.7649 39.93 146765 18045 2 1706.766389 854.3897 "Keratin, type I cytoskeletal 10 OS=Homo sapiens OX=9606 GN=KRT10 PE=1 SV=6" 9.75 3181.4 - 170960 - - - 0.8947 - 2.698 0.659 - 265.6 1 2 0 0.0015 19 0 0 0 3.37E+06 8.43E+04 - - - 6.348 0.8949 221125_WJC_METTL3_EV_vs_WT_F10.18059.18059.4 0.269 6/120 K.EQQSK[136.11]K[136.11]VSQEILELLNTTTAK[136.11].E "sp|Q86U44|MTA70_HUMAN,tr|H0YFV6|H0YFV6_HUMAN" 2 2411.3334 0 146772 18059 4 2411.340475 603.8406 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 6.33 3183.3 - 168467 - - - 2.9465 - 1.429 0.211 - 24.3 1 2 1 0.0071 21 0 0 0 7.04E+04 3.31E+07 - - - 1.1786 0.9793 221125_WJC_METTL3_EV_vs_WT_F10.18083.18083.3 0.655 Aug-80 K.EQQSK[136.11]K[136.11]VSQEILELLNTTTAK[136.11].E "sp|Q86U44|MTA70_HUMAN,tr|H0YFV6|H0YFV6_HUMAN" 2 2411.3334 0 146786 18083 3 2411.333373 804.7851 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 6.33 3186.6 - 252058 - - - 0.0012 - 1.75 0.216 - 79.3 1 2 1 0 21 0 0 0 5.12E+04 1.17E+07 - - - 2.2898 0.997 221125_WJC_METTL3_EV_vs_WT_F10.18120.18120.2 0.0613 16-Jul R.LLLPGELAK[136.11].H "sp|Q8N257|H2B3B_HUMAN,sp|A0A2R8Y619|H2BE1_HUMAN,sp|P33778|H2B1B_HUMAN,sp|Q96A08|H2B1A_HUMAN,sp|Q5QNW6|H2B2F_HUMAN,sp|P58876|H2B1D_HUMAN,sp|Q99880|H2B1L_HUMAN,sp|P62807|H2B1C_HUMAN,sp|Q99877|H2B1N_HUMAN,sp|P57053|H2BFS_HUMAN,sp|P23527|H2B1O_HUMAN,sp|O60814|H2B1K_HUMAN,sp|Q93079|H2B1H_HUMAN,sp|Q99879|H2B1M_HUMAN,sp|Q16778|H2B2E_HUMAN,sp|P06899|H2B1J_HUMAN,tr|U3KQK0|U3KQK0_HUMAN" 17 960.6099 1.82 146806 18120 2 960.611764 481.3122 Histone H2B type 3-B OS=Homo sapiens OX=9606 GN=H2BU1 PE=1 SV=3 6 3191.6 - 138797 - - - 1.9217 - 1.453 0.27 - 118.4 1 2 0 0.0018 9 0 0 0 2.51E+07 1.38E+07 - - - 2.1156 1 221125_WJC_METTL3_EV_vs_WT_F10.18137.18137.4 4.82E-16 34/204 K.ESEKPLQTGLPTGLTENQSGGPLGVDSPSAELDKK.A "sp|P78364|PHC1_HUMAN,tr|J3KQH6|J3KQH6_HUMAN" 2 3578.7952 11.76 146814 18137 4 3578.799567 895.7061 Polyhomeotic-like protein 1 OS=Homo sapiens OX=9606 GN=PHC1 PE=1 SV=3 4.36 3194 - 1.38E+06 - - - 1.2297 - 5.89 0.597 - 613.4 1 2 0 0.0044 35 0 0 0 4.99E+07 4.24E+06 - - - 4.9468 0.9934 221125_WJC_METTL3_EV_vs_WT_F10.18146.18146.2 0.194 16-Jul R.LLLPGELAK.H "sp|Q8N257|H2B3B_HUMAN,sp|A0A2R8Y619|H2BE1_HUMAN,sp|P33778|H2B1B_HUMAN,sp|Q96A08|H2B1A_HUMAN,sp|Q5QNW6|H2B2F_HUMAN,sp|P58876|H2B1D_HUMAN,sp|Q99880|H2B1L_HUMAN,sp|P62807|H2B1C_HUMAN,sp|Q99877|H2B1N_HUMAN,sp|P57053|H2BFS_HUMAN,sp|P23527|H2B1O_HUMAN,sp|O60814|H2B1K_HUMAN,sp|Q93079|H2B1H_HUMAN,sp|Q99879|H2B1M_HUMAN,sp|Q16778|H2B2E_HUMAN,sp|P06899|H2B1J_HUMAN,tr|U3KQK0|U3KQK0_HUMAN" 17 952.5957 1.82 146818 18146 2 952.596141 477.3051 Histone H2B type 3-B OS=Homo sapiens OX=9606 GN=H2BU1 PE=1 SV=3 6 3195.3 - 406391 - - - 0.444 - 1.256 0.17 - 151 1 2 0 0.0004 9 0 0 0 2.51E+07 1.38E+07 - - - 0.9559 0.8581 221125_WJC_METTL3_EV_vs_WT_F10.18178.18178.4 0.0643 6/138 K.K[136.11]SPLALLAQTC[160.03]SQIGK[136.11]PDPPPSSK[136.11].L sp|Q9H7S9|ZN703_HUMAN 1 2543.3844 1.63 146833 18178 4 2543.386141 636.8534 Zinc finger protein 703 OS=Homo sapiens OX=9606 GN=ZNF703 PE=1 SV=1 9.2 3199.5 - 197867 - - - 0.7002 - 1.328 0.109 - 12.8 1 2 0 0.0018 24 0 0 0 2.00E+07 1.23E+07 - - - 0.2653 0.9991 221125_WJC_METTL3_EV_vs_WT_F10.18184.18184.4 0.00927 8/138 K.KSPLALLAQTC[160.03]SQIGKPDPSPSSK.L sp|Q96F45|ZN503_HUMAN 1 2509.321 1.81 146835 18184 4 2509.319268 628.3375 Zinc finger protein 503 OS=Homo sapiens OX=9606 GN=ZNF503 PE=1 SV=1 9.2 3200.3 - 171032 - - - -0.6998 - 1.65 0.311 - 34.4 1 2 0 -0.0018 24 0 0 0 1.23E+07 6.77E+06 - - - 2.0932 0.9999 221125_WJC_METTL3_EV_vs_WT_F10.18214.18214.4 8.50E-07 9/174 K.SDDSQPTVWPAHDVKDDYVFEC[160.03]EAGTQYQK.T "sp|Q8NEM7|SP20H_HUMAN,tr|R4GND2|R4GND2_HUMAN,tr|F6S7C4|F6S7C4_HUMAN" 3 3514.5259 1.15 146847 18214 4 3514.533274 879.6388 Transcription factor SPT20 homolog OS=Homo sapiens OX=9606 GN=SUPT20H PE=1 SV=2 4.09 3204.5 - 761711 - - - 2.0856 - 2.51 0.567 - 40.2 1 2 1 0.0073 30 0 0 0 2.34E+07 2.03E+07 - - - 4.4407 1 221125_WJC_METTL3_EV_vs_WT_F10.18222.18222.4 1.63E-08 15/174 K.SDDSQPTVWPAHDVK[136.11]DDYVFEC[160.03]EAGTQYQK[136.11].T "sp|Q8NEM7|SP20H_HUMAN,tr|R4GND2|R4GND2_HUMAN,tr|F6S7C4|F6S7C4_HUMAN" 3 3530.5543 1.15 146850 18222 4 3530.55208 883.6459 Transcription factor SPT20 homolog OS=Homo sapiens OX=9606 GN=SUPT20H PE=1 SV=2 4.09 3205.6 - 513898 - - - -0.6413 - 2.879 0.646 - 141.5 1 2 1 -0.0023 30 0 0 0 2.34E+07 2.03E+07 - - - 5.1717 0.9994 221125_WJC_METTL3_EV_vs_WT_F10.18223.18223.4 0.000496 9/138 K.K[136.11]SPLALLAQTC[160.03]SQIGK[136.11]PDPSPSSK[136.11].L sp|Q96F45|ZN503_HUMAN 1 2533.3636 2.29 146851 18223 4 2533.358415 634.3482 Zinc finger protein 503 OS=Homo sapiens OX=9606 GN=ZNF503 PE=1 SV=1 9.2 3205.7 - 137670 - - - -2.0562 - 1.77 0.352 - 39.6 1 2 0 -0.0052 24 0 0 0 2.29E+07 9.98E+06 - - - 2.4716 1 221125_WJC_METTL3_EV_vs_WT_F10.18234.18234.3 2.77E-06 15/64 R.IINEPTAAAIAYGLDKK.G "sp|P54652|HSP72_HUMAN,sp|P11142|HSP7C_HUMAN,tr|E9PKE3|E9PKE3_HUMAN,tr|E9PN89|E9PN89_HUMAN,tr|E9PI65|E9PI65_HUMAN" 5 1786.9829 1.01 146857 18234 3 1786.982348 596.6682 Heat shock-related 70 kDa protein 2 OS=Homo sapiens OX=9606 GN=HSPA2 PE=1 SV=1 6.07 3207 - 609819 - - - -0.3089 - 2.923 0.526 - 218.7 1 2 0 -0.0006 17 0 0 0 3.51E+07 3.46E+07 - - - 7.114 0.9789 221125_WJC_METTL3_EV_vs_WT_F10.18247.18247.3 0.000901 Sep-88 A.HSALSSASTSSHNLQSIFNIGSR.G "sp|P43243|MATR3_HUMAN,tr|A8MXP9|A8MXP9_HUMAN,tr|D6R991|D6R991_HUMAN,tr|D6REK4|D6REK4_HUMAN,tr|A0A0R4J2E8|A0A0R4J2E8_HUMAN,tr|D6RCM3|D6RCM3_HUMAN,tr|D6R8Z5|D6R8Z5_HUMAN,tr|D6REM6|D6REM6_HUMAN" 8 2400.1782 1.06 146861 18247 3 2400.175223 801.0667 Matrin-3 OS=Homo sapiens OX=9606 GN=MATR3 PE=1 SV=2 9.76 3208.8 - 134408 - - - -1.2399 - 1.674 0.439 - 53.2 1 1 0 -0.003 23 0 0 0 3.33E+06 3.15E+06 - - - 4.6423 1 221125_WJC_METTL3_EV_vs_WT_F10.18249.18249.3 4.43E-08 15/64 R.IINEPTAAAIAYGLDK[136.11]K[136.11].G "sp|P54652|HSP72_HUMAN,sp|P11142|HSP7C_HUMAN,tr|E9PKE3|E9PKE3_HUMAN,tr|E9PN89|E9PN89_HUMAN,tr|E9PI65|E9PI65_HUMAN" 5 1803.0113 1.01 146862 18249 3 1803.012358 602.011 Heat shock-related 70 kDa protein 2 OS=Homo sapiens OX=9606 GN=HSPA2 PE=1 SV=1 6.07 3209.1 - 824131 - - - 0.5868 - 3.014 0.606 - 260.6 1 2 0 0.0011 17 0 0 0 3.51E+07 3.46E+07 - - - 8.0832 0.9975 221125_WJC_METTL3_EV_vs_WT_F10.18255.18255.3 6.26E-05 Aug-88 A.HSALSSASTSSHNLQSIFNIGSR[166.11].G "sp|P43243|MATR3_HUMAN,tr|A8MXP9|A8MXP9_HUMAN,tr|D6R991|D6R991_HUMAN,tr|D6REK4|D6REK4_HUMAN,tr|A0A0R4J2E8|A0A0R4J2E8_HUMAN,tr|D6RCM3|D6RCM3_HUMAN,tr|D6R8Z5|D6R8Z5_HUMAN,tr|D6REM6|D6REM6_HUMAN" 8 2410.1865 1.06 146865 18255 3 2410.185945 804.4028 Matrin-3 OS=Homo sapiens OX=9606 GN=MATR3 PE=1 SV=2 9.76 3209.8 - 123676 - - - -0.2174 - 1.908 0.608 - 57 1 1 0 -0.0005 23 0 0 0 3.33E+06 3.15E+06 - - - 6.8341 0.999 221125_WJC_METTL3_EV_vs_WT_F10.18271.18271.4 0.000144 8/126 R.TKIDC[160.03]DNLEQYFIQQGGGPDKK.G "sp|Q92499|DDX1_HUMAN,tr|A0A7I2V2M5|A0A7I2V2M5_HUMAN,tr|A0A087X2G1|A0A087X2G1_HUMAN,tr|A0A7I2V430|A0A7I2V430_HUMAN,tr|A0A7I2V4F0|A0A7I2V4F0_HUMAN,tr|A0A087WZ71|A0A087WZ71_HUMAN,tr|A0A7I2YQ77|A0A7I2YQ77_HUMAN" 7 2553.217 1.42 146869 18271 4 2553.225796 639.3115 ATP-dependent RNA helicase DDX1 OS=Homo sapiens OX=9606 GN=DDX1 PE=1 SV=2 4.68 3212.4 - 87390.8 - - - 3.4635 - 1.704 0.473 - 31.1 1 2 1 0.0088 22 0 0 0 3.21E+07 2.26E+07 - - - 3.5149 0.9969 221125_WJC_METTL3_EV_vs_WT_F10.18274.18274.4 0.00127 9/126 K.HTDESLGDC[160.03]SFLNTC[160.03]FHMDTC[160.03]K.Y "sp|Q86U44|MTA70_HUMAN,tr|H0YFV6|H0YFV6_HUMAN" 2 2674.0556 0.07 146870 18274 4 2674.038843 669.5212 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 4.64 3212.8 - 629826 - - - -6.2826 - 1.979 0.434 - 36.1 1 2 0 -0.0168 22 0 0 0 2.75E+07 3.76E+08 - - - 3.2222 1 221125_WJC_METTL3_EV_vs_WT_F10.18275.18275.4 7.04E-10 22/132 K.GRAEGEWEDQEALDYFSDKESGK.Q "sp|Q9NYF8|BCLF1_HUMAN,tr|E9PKI6|E9PKI6_HUMAN,tr|A0A1W2PQ43|A0A1W2PQ43_HUMAN,tr|E9PK91|E9PK91_HUMAN,tr|E9PK09|E9PK09_HUMAN,tr|E9PQN2|E9PQN2_HUMAN" 6 2645.1518 2.5 146871 18275 4 2645.158135 662.2952 Bcl-2-associated transcription factor 1 OS=Homo sapiens OX=9606 GN=BCLAF1 PE=1 SV=2 4.12 3212.9 - 307965 - - - 2.4067 - 3.689 0.632 - 322.7 1 2 2 0.0064 23 0 0 0 7.36E+06 2.94E+06 - - - 5.1481 0.9586 221125_WJC_METTL3_EV_vs_WT_F10.18286.18286.4 2.3 8/210 K.QPSEGAFSENNAENESGGDKPPIDPNNPAANWLHAR.S "sp|P31269|HXA9_HUMAN,tr|A0A669K9T0|A0A669K9T0_HUMAN,tr|A0A669KBC8|A0A669KBC8_HUMAN,tr|D6RAR5|D6RAR5_HUMAN" 4 3829.7317 30.62 146877 18286 4 3829.72343 958.4402 Homeobox protein Hox-A9 OS=Homo sapiens OX=9606 GN=HOXA9 PE=1 SV=4 4.35 3214.5 - 388891 - - - -2.1521 - 1.23 0.179 - 18.4 1 2 0 -0.0082 36 0 0 0 3.93E+06 1.29E+05 - - - 0.8428 0.9244 221125_WJC_METTL3_EV_vs_WT_F10.18288.18288.4 0.000498 12/132 K.DFDFESANAQFNKEEIDREFHNK.L "sp|Q8ND56|LS14A_HUMAN,tr|A0A140TA76|A0A140TA76_HUMAN,tr|K7EMZ9|K7EMZ9_HUMAN" 3 2829.2631 0.94 146879 18288 4 2830.256246 708.323 Protein LSM14 homolog A OS=Homo sapiens OX=9606 GN=LSM14A PE=1 SV=3 4.43 3214.7 - 186367 - - - 351.0437 - 1.896 0.443 - 39.8 1 2 2 0.9932 23 0 0 0 3.86E+06 4.09E+06 - - - 3.014 1 221125_WJC_METTL3_EV_vs_WT_F10.18291.18291.4 7.43E-11 19/126 R.TK[136.11]IDC[160.03]DNLEQYFIQQGGGPDK[136.11]K[136.11].G "sp|Q92499|DDX1_HUMAN,tr|A0A7I2V2M5|A0A7I2V2M5_HUMAN,tr|A0A087X2G1|A0A087X2G1_HUMAN,tr|A0A7I2V430|A0A7I2V430_HUMAN,tr|A0A7I2V4F0|A0A7I2V4F0_HUMAN,tr|A0A087WZ71|A0A087WZ71_HUMAN,tr|A0A7I2YQ77|A0A7I2YQ77_HUMAN" 7 2577.2596 1.42 146880 18291 4 2577.271239 645.3222 ATP-dependent RNA helicase DDX1 OS=Homo sapiens OX=9606 GN=DDX1 PE=1 SV=2 4.68 3215.1 - 468316 - - - 4.5343 - 3.769 0.632 - 230.5 1 2 1 0.0117 22 0 0 0 3.21E+07 2.26E+07 - - - 5.1578 0.9819 221125_WJC_METTL3_EV_vs_WT_F10.18292.18292.4 0.0201 13/186 R.TPESSGSGSGGGGKRPAVPAAVSLLPPADPLR.Q sp|Q9H7S9|ZN703_HUMAN 1 2984.5679 2.04 146881 18292 4 2984.582723 747.1493 Zinc finger protein 703 OS=Homo sapiens OX=9606 GN=ZNF703 PE=1 SV=1 8.41 3215.3 - 51851.3 - - - 4.9505 - 1.994 0.355 - 54.2 1 2 1 0.0148 32 0 0 0 2.04E+06 1.00E+06 - - - 2.5202 1 221125_WJC_METTL3_EV_vs_WT_F10.18300.18300.4 1.29E-14 21/126 R.TK[136.11]IDC[160.03]DNLEQYFIQQGGGPDK[136.11]K[136.11].G "sp|Q92499|DDX1_HUMAN,tr|A0A7I2V2M5|A0A7I2V2M5_HUMAN,tr|A0A087X2G1|A0A087X2G1_HUMAN,tr|A0A7I2V430|A0A7I2V430_HUMAN,tr|A0A7I2V4F0|A0A7I2V4F0_HUMAN,tr|A0A087WZ71|A0A087WZ71_HUMAN,tr|A0A7I2YQ77|A0A7I2YQ77_HUMAN" 7 2577.2596 1.42 146885 18300 4 2577.26925 645.3222 ATP-dependent RNA helicase DDX1 OS=Homo sapiens OX=9606 GN=DDX1 PE=1 SV=2 4.68 3216.3 - 827914 - - - 3.7625 - 3.966 0.675 - 386.9 1 2 1 0.0097 22 0 0 0 3.21E+07 2.26E+07 - - - 5.5493 1 221125_WJC_METTL3_EV_vs_WT_F10.18305.18305.3 1.27E-10 17/84 R.TKIDC[160.03]DNLEQYFIQQGGGPDKK.G "sp|Q92499|DDX1_HUMAN,tr|A0A7I2V2M5|A0A7I2V2M5_HUMAN,tr|A0A087X2G1|A0A087X2G1_HUMAN,tr|A0A7I2V430|A0A7I2V430_HUMAN,tr|A0A7I2V4F0|A0A7I2V4F0_HUMAN,tr|A0A087WZ71|A0A087WZ71_HUMAN,tr|A0A7I2YQ77|A0A7I2YQ77_HUMAN" 7 2553.217 2.61 146888 18305 3 2553.221553 852.0796 ATP-dependent RNA helicase DDX1 OS=Homo sapiens OX=9606 GN=DDX1 PE=1 SV=2 4.68 3217 - 170092 - - - 1.8016 - 3.905 0.671 - 384.5 1 2 1 0.0046 22 0 0 0 5.85E+06 2.24E+06 - - - 9.2494 0.9603 221125_WJC_METTL3_EV_vs_WT_F10.18318.18318.3 0.433 May-36 R.K[136.11]QDSGHLDLR[166.11].N "sp|Q86U44|MTA70_HUMAN,tr|B4E349|B4E349_HUMAN,tr|F5H6D8|F5H6D8_HUMAN,tr|B4DTN4|B4DTN4_HUMAN" 4 1185.6221 0.03 146895 18318 3 1185.624988 396.2146 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 6.75 3218.9 - 56886.6 - - - 2.4316 - 1.128 0.237 - 37.6 1 2 0 0.0029 10 0 0 0 2.16E+05 7.63E+06 - - - 1.5333 1 221125_WJC_METTL3_EV_vs_WT_F10.18320.18320.2 3.43E-11 22-Nov K.SFFDNISC[160.03]DDNR.E "sp|Q8ND56|LS14A_HUMAN,tr|A0A096LP11|A0A096LP11_HUMAN,tr|A0A140TA76|A0A140TA76_HUMAN,tr|A0A0G2JQ95|A0A0G2JQ95_HUMAN" 4 1488.594 0.6 146897 18320 2 1488.590761 745.3043 Protein LSM14 homolog A OS=Homo sapiens OX=9606 GN=LSM14A PE=1 SV=3 3.93 3219.2 - 92874.4 - - - -2.147 - 2.45 0.734 - 401.6 1 2 0 -0.0032 12 0 0 0 2.69E+06 4.51E+06 - - - 6.8191 0.953 221125_WJC_METTL3_EV_vs_WT_F10.18329.18329.4 0.0309 6/144 R.AGSHISSNR[166.11]AYDFLYELTLLFR[166.11]C[160.03]LK[136.11].K tr|F8WEV1|F8WEV1_HUMAN 1 3001.5478 0.02 146902 18329 4 3001.551888 751.3942 Cilia- and flagella-associated protein 91 OS=Homo sapiens OX=9606 GN=CFAP91 PE=1 SV=1 8.23 3220.4 - 315041 - - - 1.3493 - 1.406 0.289 - 7.7 9 2 2 0.004 25 0 0 0 5.06E+06 2.84E+08 - - - 1.1215 0.9906 221125_WJC_METTL3_EV_vs_WT_F10.18339.18339.3 0.0122 May-84 K.KQISNLQQSISDAEQRGENALK.D sp|P04264|K2C1_HUMAN 1 2456.2619 999 146907 18339 3 2456.265521 819.7613 "Keratin, type II cytoskeletal 1 OS=Homo sapiens OX=9606 GN=KRT1 PE=1 SV=6" 6.18 3221.8 - 162588 - - - 1.4624 - 1.417 0.33 - 18.6 1 2 1 0.0036 22 0 0 0 4.91E+07 0.00E+00 - - - 3.0445 1 221125_WJC_METTL3_EV_vs_WT_F10.18343.18343.4 5.30E-07 10/234 K.SQSVSVSGPGPGPGPGLC[160.03]PGPNVLLNQQNPPAPQPQHLAR.R sp|Q9H0L4|CSTFT_HUMAN 1 4006.0232 4.49 146909 18343 4 4006.022918 1002.5131 Cleavage stimulation factor subunit 2 tau variant OS=Homo sapiens OX=9606 GN=CSTF2T PE=1 SV=1 7.99 3222.3 - 308395 - - - -0.0622 - 2.677 0.563 - 22.9 1 2 0 -0.0002 40 0 0 0 3.62E+07 8.06E+06 - - - 4.4105 1 221125_WJC_METTL3_EV_vs_WT_F10.18347.18347.4 3.94E-09 18/126 K.KQISNLQQSISDAEQRGENALK.D sp|P04264|K2C1_HUMAN 1 2456.2619 999 146911 18347 4 2456.269644 615.0728 "Keratin, type II cytoskeletal 1 OS=Homo sapiens OX=9606 GN=KRT1 PE=1 SV=6" 6.18 3222.8 - 592209 - - - 3.141 - 3.387 0.628 - 200.7 1 2 1 0.0077 22 0 0 0 1.04E+08 0.00E+00 - - - 5.0891 1 221125_WJC_METTL3_EV_vs_WT_F10.18360.18360.4 1.27E-06 17/198 R.SDSPVPTAPTSGGPK[136.11]PSTASAVPELATDPELEK[136.11]K[136.11].L "sp|Q86U44|MTA70_HUMAN,tr|B4E349|B4E349_HUMAN,tr|F5H6D8|F5H6D8_HUMAN,tr|B4DTN4|B4DTN4_HUMAN" 4 3384.7363 0.001 146918 18360 4 3384.735667 847.1913 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 4.51 3224.5 - 941718 - - - -0.1755 - 3.003 0.474 - 93.9 1 2 0 -0.0006 34 0 0 0 0.00E+00 3.90E+07 - - - 3.6794 0.9959 221125_WJC_METTL3_EV_vs_WT_F10.18363.18363.2 0.288 16-Jul R.LGSLVDEFK[136.11].E "sp|P12956|XRCC6_HUMAN,tr|B1AHC9|B1AHC9_HUMAN" 2 1014.5477 0.26 146921 18363 2 1014.546629 508.2811 X-ray repair cross-complementing protein 6 OS=Homo sapiens OX=9606 GN=XRCC6 PE=1 SV=2 4.37 3224.9 - 145436 - - - -1.0675 - 1.294 0.219 - 102 1 2 0 -0.0011 9 0 0 0 1.34E+06 5.27E+06 - - - 1.4038 0.9981 221125_WJC_METTL3_EV_vs_WT_F10.18369.18369.4 7.31E-07 15/156 N.QQGAHSALSSASTSSHNLQSIFNIGSR.G "sp|P43243|MATR3_HUMAN,tr|A8MXP9|A8MXP9_HUMAN,tr|D6R991|D6R991_HUMAN,tr|D6REK4|D6REK4_HUMAN,tr|A0A0R4J2E8|A0A0R4J2E8_HUMAN,tr|D6RCM3|D6RCM3_HUMAN,tr|D6R8Z5|D6R8Z5_HUMAN,tr|D6REM6|D6REM6_HUMAN" 8 2784.3539 1.34 146924 18369 4 2784.356677 697.0958 Matrin-3 OS=Homo sapiens OX=9606 GN=MATR3 PE=1 SV=2 9.76 3225.8 - 425680 - - - 0.9859 - 2.859 0.595 - 107.7 1 1 0 0.0027 27 0 0 0 8.28E+07 6.17E+07 - - - 4.7328 0.9997 221125_WJC_METTL3_EV_vs_WT_F10.18375.18375.4 0.00421 11/240 K.EGGTASVATGPDSPSPVPLPPGKPALPGADGTPFGC[160.03]PPGRK.E "sp|Q6SPF0|SAMD1_HUMAN,tr|E9PIW9|E9PIW9_HUMAN,tr|F8WDT5|F8WDT5_HUMAN" 3 3892.9418 3.3 146927 18375 4 3892.939099 974.2427 Sterile alpha motif domain-containing protein 1 OS=Homo sapiens OX=9606 GN=SAMD1 PE=1 SV=1 6.21 3226.6 - 215565 - - - -0.6907 - 2.254 0.363 - 21.1 1 2 0 -0.0027 41 0 0 0 6.42E+06 1.94E+06 - - - 2.6183 1 221125_WJC_METTL3_EV_vs_WT_F10.18392.18392.4 4.75E-09 15/156 K.IGEEQSPEDAEDGPPELLFIHGGHTAK.L "sp|Q09028|RBBP4_HUMAN,tr|H0YCT5|H0YCT5_HUMAN,tr|H0YDK2|H0YDK2_HUMAN,tr|H0YEU5|H0YEU5_HUMAN,tr|H0YF10|H0YF10_HUMAN" 5 2872.3515 1.97 146934 18392 4 2872.351965 719.0952 Histone-binding protein RBBP4 OS=Homo sapiens OX=9606 GN=RBBP4 PE=1 SV=3 4.24 3228.9 - 334384 - - - 0.1507 - 3.003 0.616 - 116.8 1 2 0 0.0004 27 0 0 0 1.22E+07 6.21E+06 - - - 4.9316 1 221125_WJC_METTL3_EV_vs_WT_F10.18393.18393.3 7.54E-16 21/112 Q.HSQSGSTTTSSWDMGSTTQSPSLVQYDLK.N "sp|Q14157|UBP2L_HUMAN,tr|F8W726|F8W726_HUMAN" 2 3115.404 1.85 146935 18393 3 3115.407469 1039.4753 Ubiquitin-associated protein 2-like OS=Homo sapiens OX=9606 GN=UBAP2L PE=1 SV=2 5.21 3229 - 303891 - - - 1.1013 - 4.031 0.731 - 391.2 1 1 0 0.0034 29 0 0 0 4.50E+06 2.44E+06 - - - 9.8961 1 221125_WJC_METTL3_EV_vs_WT_F10.18404.18404.4 2.84E-09 31/156 N.QQGAHSALSSASTSSHNLQSIFNIGSR[166.11].G "sp|P43243|MATR3_HUMAN,tr|A8MXP9|A8MXP9_HUMAN,tr|D6R991|D6R991_HUMAN,tr|D6REK4|D6REK4_HUMAN,tr|A0A0R4J2E8|A0A0R4J2E8_HUMAN,tr|D6RCM3|D6RCM3_HUMAN,tr|D6R8Z5|D6R8Z5_HUMAN,tr|D6REM6|D6REM6_HUMAN" 8 2794.3622 1.34 146942 18404 4 2794.362411 699.5978 Matrin-3 OS=Homo sapiens OX=9606 GN=MATR3 PE=1 SV=2 9.76 3230.4 - 1.76E+06 - - - 0.0748 - 4.746 0.626 - 511.4 1 1 0 0.0002 27 0 0 0 8.27E+07 6.17E+07 - - - 5.1619 0.9974 221125_WJC_METTL3_EV_vs_WT_F10.18405.18405.3 0.0203 Jul-64 R.GAPPSSNIEDFHGLLPK.G "sp|P43243|MATR3_HUMAN,tr|A8MXP9|A8MXP9_HUMAN,tr|D6R991|D6R991_HUMAN,tr|A0A0R4J2E8|A0A0R4J2E8_HUMAN,tr|H0Y8T4|H0Y8T4_HUMAN,tr|D6REM6|D6REM6_HUMAN" 6 1777.8999 1.42 146943 18405 3 1777.900263 593.6406 Matrin-3 OS=Homo sapiens OX=9606 GN=MATR3 PE=1 SV=2 5.32 3230.6 - 124709 - - - 0.2047 - 1.399 0.294 - 36.2 1 2 0 0.0004 17 0 0 0 2.02E+07 1.42E+07 - - - 2.6659 1 221125_WJC_METTL3_EV_vs_WT_F10.18408.18408.4 1.60E-11 19/162 L.NQQGAHSALSSASTSSHNLQSIFNIGSR.G "sp|P43243|MATR3_HUMAN,tr|A8MXP9|A8MXP9_HUMAN,tr|D6R991|D6R991_HUMAN,tr|D6REK4|D6REK4_HUMAN,tr|A0A0R4J2E8|A0A0R4J2E8_HUMAN,tr|D6RCM3|D6RCM3_HUMAN,tr|D6R8Z5|D6R8Z5_HUMAN,tr|D6REM6|D6REM6_HUMAN" 8 2898.3969 1.43 146944 18408 4 2898.400533 725.6065 Matrin-3 OS=Homo sapiens OX=9606 GN=MATR3 PE=1 SV=2 9.76 3231 - 530858 - - - 1.2676 - 3.544 0.629 - 189.3 1 1 0 0.0037 28 0 0 0 8.41E+07 5.88E+07 - - - 5.0926 0.9984 221125_WJC_METTL3_EV_vs_WT_F10.18409.18409.3 3.74E-10 15/104 N.QQGAHSALSSASTSSHNLQSIFNIGSR.G "sp|P43243|MATR3_HUMAN,tr|A8MXP9|A8MXP9_HUMAN,tr|D6R991|D6R991_HUMAN,tr|D6REK4|D6REK4_HUMAN,tr|A0A0R4J2E8|A0A0R4J2E8_HUMAN,tr|D6RCM3|D6RCM3_HUMAN,tr|D6R8Z5|D6R8Z5_HUMAN,tr|D6REM6|D6REM6_HUMAN" 8 2784.3539 1.19 146945 18409 3 2784.349889 929.1253 Matrin-3 OS=Homo sapiens OX=9606 GN=MATR3 PE=1 SV=2 9.76 3231.1 - 286168 - - - -1.452 - 2.538 0.645 - 138.5 1 1 0 -0.004 27 0 0 0 7.47E+06 6.25E+06 - - - 7.8727 0.9999 221125_WJC_METTL3_EV_vs_WT_F10.18410.18410.3 7.72E-07 15/52 K.NKLNDLEDALQQAK.E sp|P04264|K2C1_HUMAN 1 1598.8264 1148.79 146946 18410 3 1598.826703 533.9494 "Keratin, type II cytoskeletal 1 OS=Homo sapiens OX=9606 GN=KRT1 PE=1 SV=6" 4.56 3231.2 - 283325 - - - 0.1895 - 2.207 0.566 - 222.1 1 2 1 0.0003 14 0 0 0 4.70E+07 4.09E+04 - - - 6.954 0.9424 221125_WJC_METTL3_EV_vs_WT_F10.18411.18411.2 0.000175 26-Sep K.NKLNDLEDALQQAK.E sp|P04264|K2C1_HUMAN 1 1598.8264 999 146947 18411 2 1598.833823 800.4205 "Keratin, type II cytoskeletal 1 OS=Homo sapiens OX=9606 GN=KRT1 PE=1 SV=6" 4.56 3231.4 - 115515 - - - 4.6428 - 1.975 0.357 - 218.1 1 2 1 0.0074 14 0 0 0 1.27E+07 0.00E+00 - - - 3.3833 0.9997 221125_WJC_METTL3_EV_vs_WT_F10.18414.18414.4 2.97E-05 Dec-96 R.HGDSLKEIKIEISELNR.V sp|P35908|K22E_HUMAN 1 1980.064 79.98 146948 18414 4 1980.061727 496.0233 "Keratin, type II cytoskeletal 2 epidermal OS=Homo sapiens OX=9606 GN=KRT2 PE=1 SV=2" 5.53 3231.8 - 84893.6 - - - -1.15 - 2.243 0.447 - 137 1 2 2 -0.0023 17 0 0 0 4.22E+06 5.28E+04 - - - 3.3965 0.9988 221125_WJC_METTL3_EV_vs_WT_F10.18416.18416.3 3.43E-08 13/104 N.QQGAHSALSSASTSSHNLQSIFNIGSR[166.11].G "sp|P43243|MATR3_HUMAN,tr|A8MXP9|A8MXP9_HUMAN,tr|D6R991|D6R991_HUMAN,tr|D6REK4|D6REK4_HUMAN,tr|A0A0R4J2E8|A0A0R4J2E8_HUMAN,tr|D6RCM3|D6RCM3_HUMAN,tr|D6R8Z5|D6R8Z5_HUMAN,tr|D6REM6|D6REM6_HUMAN" 8 2794.3622 1.19 146949 18416 3 2794.35948 932.4613 Matrin-3 OS=Homo sapiens OX=9606 GN=MATR3 PE=1 SV=2 9.76 3232 - 196763 - - - -0.9741 - 2.655 0.641 - 88.9 1 1 0 -0.0027 27 0 0 0 7.47E+06 6.25E+06 - - - 7.9322 0.9999 221125_WJC_METTL3_EV_vs_WT_F10.18418.18418.4 4.84E-10 23/132 K.DFDFESANAQFNK[136.11]EEIDR[166.11]EFHNK[136.11].L "sp|Q8ND56|LS14A_HUMAN,tr|A0A140TA76|A0A140TA76_HUMAN,tr|K7EMZ9|K7EMZ9_HUMAN" 3 2855.2997 0.98 146951 18418 4 2855.300842 714.8322 Protein LSM14 homolog A OS=Homo sapiens OX=9606 GN=LSM14A PE=1 SV=3 4.43 3232.3 - 881074 - - - 0.3926 - 3.796 0.572 - 163 1 2 2 0.0011 23 0 0 0 7.00E+08 7.12E+08 - - - 4.6366 1 221125_WJC_METTL3_EV_vs_WT_F10.18421.18421.4 4.38E-09 13/156 K.IGEEQSPEDAEDGPPELLFIHGGHTAK[136.11].L "sp|Q09028|RBBP4_HUMAN,tr|H0YCT5|H0YCT5_HUMAN,tr|H0YDK2|H0YDK2_HUMAN,tr|H0YEU5|H0YEU5_HUMAN,tr|H0YF10|H0YF10_HUMAN" 5 2880.3657 2.49 146952 18421 4 2880.368527 721.0987 Histone-binding protein RBBP4 OS=Homo sapiens OX=9606 GN=RBBP4 PE=1 SV=3 4.24 3232.7 - 235505 - - - 0.9704 - 3.039 0.643 - 87.1 1 2 0 0.0028 27 0 0 0 1.20E+07 4.83E+06 - - - 5.1697 0.999 221125_WJC_METTL3_EV_vs_WT_F10.18427.18427.3 1.41E-05 Aug-88 K.DFDFESANAQFNKEEIDREFHNK.L "sp|Q8ND56|LS14A_HUMAN,tr|A0A140TA76|A0A140TA76_HUMAN,tr|K7EMZ9|K7EMZ9_HUMAN" 3 2829.2631 1.02 146956 18427 3 2829.253148 944.095 Protein LSM14 homolog A OS=Homo sapiens OX=9606 GN=LSM14A PE=1 SV=3 4.43 3233.5 - 71431.8 - - - -3.5002 - 1.958 0.546 - 39.5 1 2 2 -0.0099 23 0 0 0 5.51E+07 5.39E+07 - - - 6.2009 1 221125_WJC_METTL3_EV_vs_WT_F10.18435.18435.3 2.44E-08 15/88 K.DFDFESANAQFNK[136.11]EEIDR[166.11]EFHNK[136.11].L "sp|Q8ND56|LS14A_HUMAN,tr|A0A140TA76|A0A140TA76_HUMAN,tr|K7EMZ9|K7EMZ9_HUMAN" 3 2855.2997 1.02 146961 18435 3 2855.301447 952.7739 Protein LSM14 homolog A OS=Homo sapiens OX=9606 GN=LSM14A PE=1 SV=3 4.43 3234.5 - 239305 - - - 0.6045 - 3.156 0.707 - 164.7 1 2 2 0.0017 23 0 0 0 5.51E+07 5.39E+07 - - - 9.1181 1 221125_WJC_METTL3_EV_vs_WT_F10.18441.18441.4 4.37E-14 33/162 L.NQQGAHSALSSASTSSHNLQSIFNIGSR[166.11].G "sp|P43243|MATR3_HUMAN,tr|A8MXP9|A8MXP9_HUMAN,tr|D6R991|D6R991_HUMAN,tr|D6REK4|D6REK4_HUMAN,tr|A0A0R4J2E8|A0A0R4J2E8_HUMAN,tr|D6RCM3|D6RCM3_HUMAN,tr|D6R8Z5|D6R8Z5_HUMAN,tr|D6REM6|D6REM6_HUMAN" 8 2908.4051 1.43 146963 18441 4 2908.40242 728.1086 Matrin-3 OS=Homo sapiens OX=9606 GN=MATR3 PE=1 SV=2 9.76 3235.4 - 1.97E+06 - - - -0.9314 - 4.806 0.714 - 564.3 1 1 0 -0.0027 28 0 0 0 8.41E+07 5.88E+07 - - - 5.9273 0.9961 221125_WJC_METTL3_EV_vs_WT_F10.18448.18448.4 3.22E-06 10/144 Q.GAHSALSSASTSSHNLQSIFNIGSR.G "sp|P43243|MATR3_HUMAN,tr|A8MXP9|A8MXP9_HUMAN,tr|D6R991|D6R991_HUMAN,tr|D6REK4|D6REK4_HUMAN,tr|A0A0R4J2E8|A0A0R4J2E8_HUMAN,tr|D6RCM3|D6RCM3_HUMAN,tr|D6R8Z5|D6R8Z5_HUMAN,tr|D6REM6|D6REM6_HUMAN" 8 2528.2368 1.44 146966 18448 4 2528.23574 633.0665 Matrin-3 OS=Homo sapiens OX=9606 GN=MATR3 PE=1 SV=2 9.76 3236.4 - 220726 - - - -0.4102 - 2.094 0.518 - 46.3 1 1 0 -0.001 25 0 0 0 5.51E+06 3.84E+06 - - - 3.9695 1 221125_WJC_METTL3_EV_vs_WT_F10.18511.18511.4 6.06E-19 33/132 K.DFDFESANAQFNKEEIDREFHNK.L "sp|Q8ND56|LS14A_HUMAN,tr|A0A140TA76|A0A140TA76_HUMAN,tr|K7EMZ9|K7EMZ9_HUMAN" 3 2829.2631 0.98 146991 18511 4 2829.272011 708.323 Protein LSM14 homolog A OS=Homo sapiens OX=9606 GN=LSM14A PE=1 SV=3 4.43 3245 - 4.50E+06 - - - 3.1669 - 5.71 0.67 - 430.4 1 2 2 0.009 23 0 0 0 7.00E+08 7.12E+08 - - - 5.6197 0.9999 221125_WJC_METTL3_EV_vs_WT_F10.18516.18516.4 2.28E-06 11/156 K.KQSHAASAAPQASSPPDYTMAWAEYYR.Q sp|Q96I24|FUBP3_HUMAN 1 2983.3559 1.92 146994 18516 4 2983.362173 746.8463 Far upstream element-binding protein 3 OS=Homo sapiens OX=9606 GN=FUBP3 PE=1 SV=2 6.75 3245.7 - 230296 - - - 2.1007 - 2.822 0.513 - 62.6 1 2 0 0.0063 27 0 0 0 7.65E+06 3.98E+06 - - - 4.014 0.9886 221125_WJC_METTL3_EV_vs_WT_F10.18517.18517.3 0.00992 Jul-44 R.FATSEELLSHLR.T "sp|Q9H7S9|ZN703_HUMAN,sp|Q96F45|ZN503_HUMAN" 2 1401.7252 1.42 146995 18517 3 1401.727637 468.249 Zinc finger protein 703 OS=Homo sapiens OX=9606 GN=ZNF703 PE=1 SV=1 5.4 3245.8 - 90145 - - - 1.7179 - 1.349 0.238 - 44.1 1 2 0 0.0024 12 0 0 0 1.98E+06 1.39E+06 - - - 2.0226 1 221125_WJC_METTL3_EV_vs_WT_F10.18526.18526.3 8.84E-15 16/140 R.GTSTSRPLNATATPLSGVSYEDDFVSSPGTGTSTEK.K sp|Q5VT06|CE350_HUMAN 1 3616.7017 2.7 147002 18526 3 3616.718894 1206.5745 Centrosome-associated protein 350 OS=Homo sapiens OX=9606 GN=CEP350 PE=1 SV=1 4.32 3247 - 110619 - - - 4.7651 - 3.199 0.763 - 130.9 1 2 0 0.0172 36 0 0 0 3.14E+06 1.16E+06 - - - 9.7172 0.9999 221125_WJC_METTL3_EV_vs_WT_F10.18536.18536.3 0.00643 7/140 R.GTSTSR[166.11]PLNATATPLSGVSYEDDFVSSPGTGTSTEK[136.11].K sp|Q5VT06|CE350_HUMAN 1 3634.7241 2.7 147008 18536 3 3634.730044 1212.582 Centrosome-associated protein 350 OS=Homo sapiens OX=9606 GN=CEP350 PE=1 SV=1 4.32 3248.3 - 89435.8 - - - 1.6271 - 1.54 0.521 - 22.9 1 2 0 0.0059 36 0 0 0 3.14E+06 1.16E+06 - - - 5.3404 1 221125_WJC_METTL3_EV_vs_WT_F10.18548.18548.3 2.70E-08 Sep-52 K.HTTSIFDDFAHYEK[136.11].R "sp|Q9BYJ9|YTHD1_HUMAN,sp|Q7Z739|YTHD3_HUMAN,tr|A0A087X0Q1|A0A087X0Q1_HUMAN,tr|A0A024R7W5|A0A024R7W5_HUMAN,tr|A0A087WY31|A0A087WY31_HUMAN" 5 1717.7828 1.61 147016 18548 3 1717.783865 573.6015 YTH domain-containing family protein 1 OS=Homo sapiens OX=9606 GN=YTHDF1 PE=1 SV=1 5.21 3250 - 113567 - - - 0.6491 - 2.334 0.624 - 59.1 1 2 0 0.0011 14 0 0 0 6.01E+06 3.74E+06 - - - 7.7492 0.999 221125_WJC_METTL3_EV_vs_WT_F10.18553.18553.2 0.0145 18-Jul K.FAAQELIEVK[136.11].R "sp|Q86U44|MTA70_HUMAN,tr|F5H6D8|F5H6D8_HUMAN,tr|H0YFV6|H0YFV6_HUMAN,tr|B4DTN4|B4DTN4_HUMAN" 4 1154.6427 0.02 147018 18553 2 1154.643215 578.3286 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 4.53 3250.8 - 140919 - - - 0.4677 - 1.601 0.286 - 113.1 1 2 0 0.0005 10 0 0 0 5.97E+06 2.82E+08 - - - 2.4669 0.9797 221125_WJC_METTL3_EV_vs_WT_F10.18556.18556.3 0.209 Jun-36 R.K[136.11]QDSGHLDLR[166.11].N "sp|Q86U44|MTA70_HUMAN,tr|B4E349|B4E349_HUMAN,tr|F5H6D8|F5H6D8_HUMAN,tr|B4DTN4|B4DTN4_HUMAN" 4 1185.6221 0.05 147021 18556 3 1185.624795 396.2146 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 6.75 3251.2 - 51142.3 - - - 2.2689 - 1.149 0.263 - 60.5 1 2 0 0.0027 10 0 0 0 6.22E+04 1.14E+06 - - - 1.8771 1 221125_WJC_METTL3_EV_vs_WT_F10.18565.18565.3 1.06E-11 Dec-52 K.HTTSIFDDFAHYEK.R "sp|Q9BYJ9|YTHD1_HUMAN,sp|Q7Z739|YTHD3_HUMAN,tr|A0A087X0Q1|A0A087X0Q1_HUMAN,tr|A0A024R7W5|A0A024R7W5_HUMAN,tr|A0A087WY31|A0A087WY31_HUMAN" 5 1709.7686 1.62 147025 18565 3 1709.772656 570.9301 YTH domain-containing family protein 1 OS=Homo sapiens OX=9606 GN=YTHDF1 PE=1 SV=1 5.21 3252.5 - 244177 - - - 2.4015 - 2.933 0.67 - 122.7 1 2 0 0.0041 14 0 0 0 6.12E+06 3.78E+06 - - - 8.8683 0.971 221125_WJC_METTL3_EV_vs_WT_F10.18569.18569.4 0.0797 8/120 K.EQQSK[136.11]K[136.11]VSQEILELLNTTTAK[136.11].E "sp|Q86U44|MTA70_HUMAN,tr|H0YFV6|H0YFV6_HUMAN" 2 2411.3334 0.001 147027 18569 4 2411.333627 603.8406 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 6.33 3253.1 - 248163 - - - 0.1066 - 1.616 0.217 - 44.2 1 2 1 0.0003 21 0 0 0 0.00E+00 8.24E+06 - - - 1.2734 0.9952 221125_WJC_METTL3_EV_vs_WT_F10.18638.18638.4 0.000999 11/168 R.KVPGVTAIDLDEDTC[160.03]TFHIYGEDQDAVKK.A "sp|Q06787|FMR1_HUMAN,tr|A0A087WY29|A0A087WY29_HUMAN,tr|R9WNI0|R9WNI0_HUMAN,tr|A8MQB8|A8MQB8_HUMAN,tr|A0A087WWR6|A0A087WWR6_HUMAN,tr|A0A087WXI3|A0A087WXI3_HUMAN,tr|Q8IXW7|Q8IXW7_HUMAN,tr|G3V0J0|G3V0J0_HUMAN" 8 3263.5656 0.92 147065 18638 4 3263.581524 816.8987 Synaptic functional regulator FMR1 OS=Homo sapiens OX=9606 GN=FMR1 PE=1 SV=1 4.32 3262.9 - 140980 - - - 4.872 - 1.86 0.351 - 35.5 1 2 0 0.0159 29 0 0 0 4.19E+06 4.56E+06 - - - 2.468 0.999 221125_WJC_METTL3_EV_vs_WT_F10.18639.18639.4 0.000767 5/168 R.K[136.11]VPGVTAIDLDEDTC[160.03]TFHIYGEDQDAVK[136.11]K[136.11].A "sp|Q06787|FMR1_HUMAN,tr|A0A087WY29|A0A087WY29_HUMAN,tr|R9WNI0|R9WNI0_HUMAN,tr|A8MQB8|A8MQB8_HUMAN,tr|A0A087WWR6|A0A087WWR6_HUMAN,tr|A0A087WXI3|A0A087WXI3_HUMAN,tr|Q8IXW7|Q8IXW7_HUMAN,tr|G3V0J0|G3V0J0_HUMAN" 8 3287.6082 1.04 147066 18639 4 3287.625507 822.9093 Synaptic functional regulator FMR1 OS=Homo sapiens OX=9606 GN=FMR1 PE=1 SV=1 4.32 3263.1 - 109568 - - - 5.257 - 1.391 0.479 - 11.5 1 2 0 0.0173 29 0 0 0 4.16E+06 3.99E+06 - - - 3.4921 0.9997 221125_WJC_METTL3_EV_vs_WT_F10.18644.18644.4 2.05E-06 18/198 R.SDSPVPTAPTSGGPK[136.11]PSTASAVPELATDPELEK[136.11]K[136.11].L "sp|Q86U44|MTA70_HUMAN,tr|B4E349|B4E349_HUMAN,tr|F5H6D8|F5H6D8_HUMAN,tr|B4DTN4|B4DTN4_HUMAN" 4 3384.7363 0 147069 18644 4 3384.749485 847.1913 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 4.51 3263.7 - 587567 - - - 3.907 - 3.347 0.466 - 123.2 1 2 0 0.0132 34 0 0 0 4.27E+04 3.93E+07 - - - 3.6387 0.9998 221125_WJC_METTL3_EV_vs_WT_F10.18648.18648.4 0.00372 8/120 R.K[136.11]HAASDVDLEIESLLNQQSTK[136.11].E "sp|Q86U44|MTA70_HUMAN,tr|F5H6D8|F5H6D8_HUMAN,tr|H0YFV6|H0YFV6_HUMAN,tr|B4DTN4|B4DTN4_HUMAN" 4 2341.2096 0.01 147071 18648 4 2341.217442 586.3097 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 4.75 3264.2 - 146964 - - - 3.3414 - 1.927 0.482 - 38.7 1 2 0 0.0078 21 0 0 0 1.24E+05 1.10E+07 - - - 3.636 0.918 221125_WJC_METTL3_EV_vs_WT_F10.18650.18650.4 0.1 10/180 R.KMFRALMPALEELTFDPSSAHPSLVVSSSGR[166.11].R sp|Q6ZMU5|TRI72_HUMAN 1 3369.7089 - 147072 18650 4 3369.705734 843.4345 Tripartite motif-containing protein 72 OS=Homo sapiens OX=9606 GN=TRIM72 PE=1 SV=2 6.76 3264.5 - 280613 - - - -0.936 - 1.877 0.17 - 26.1 1 2 1 -0.0032 31 0 0 0 - - - - - 0.8962 0.9943 221125_WJC_METTL3_EV_vs_WT_F10.18652.18652.4 7.69E-05 8/162 R.DSSR[166.11]LPSEGPR[166.11]PAHVVVGDVLQAADVDK[136.11].T "sp|P30043|BLVRB_HUMAN,tr|A0A2R8YEP4|A0A2R8YEP4_HUMAN,tr|A0A2R8Y7Y9|A0A2R8Y7Y9_HUMAN,tr|M0R192|M0R192_HUMAN,tr|M0QZL1|M0QZL1_HUMAN" 5 2941.5252 0.75 147073 18652 4 2941.542609 736.3886 Flavin reductase (NADPH) OS=Homo sapiens OX=9606 GN=BLVRB PE=1 SV=3 4.75 3264.7 - 45529.5 - - - 5.9224 - 2.115 0.471 - 27.7 1 2 1 0.0174 28 0 0 0 8.44E+05 1.12E+06 - - - 3.5533 0.9981 221125_WJC_METTL3_EV_vs_WT_F10.18677.18677.3 3.44E-06 Nov-80 K.ADRDESSPYAAMLAAQDVAQR.C "sp|P62263|RS14_HUMAN,tr|A0A2R8Y811|A0A2R8Y811_HUMAN,tr|E5RH77|E5RH77_HUMAN" 3 2264.0492 1.02 147083 18677 3 2264.061778 755.6903 40S ribosomal protein S14 OS=Homo sapiens OX=9606 GN=RPS14 PE=1 SV=3 4.23 3268.3 - 85319.4 - - - 5.5736 - 2.608 0.58 - 105.1 1 2 1 0.0126 21 0 0 0 7.06E+06 6.91E+06 - - - 7.3011 0.9539 221125_WJC_METTL3_EV_vs_WT_F10.18705.18705.4 0.0554 May-96 R.K[136.11]K[136.11]DASDDLDDLNFFNQK[136.11].K sp|P20042|IF2B_HUMAN 1 2035.9913 0.73 147097 18705 4 2036.000876 510.0051 Eukaryotic translation initiation factor 2 subunit 2 OS=Homo sapiens OX=9606 GN=EIF2S2 PE=1 SV=2 4.28 3272.3 - 89749.9 - - - 4.7034 - 1.13 0.315 - 15.2 1 2 1 0.0096 17 0 0 0 1.99E+06 2.71E+06 - - - 2.0075 0.8893 221125_WJC_METTL3_EV_vs_WT_F10.18719.18719.4 0.0565 6/174 K.VDRQPSGDSGLAAETSAISQDLEGVPPSKK.M sp|Q4VC05|BCL7A_HUMAN 1 3038.5156 3.74 147104 18719 4 3038.5235 760.6362 B-cell CLL\lymphoma 7 protein family member A OS=Homo sapiens OX=9606 GN=BCL7A PE=1 SV=1 4.44 3274.3 - 137976 - - - 2.5878 - 1.225 0.205 - 10.9 1 2 1 0.0079 30 0 0 0 1.27E+07 3.40E+06 - - - 1.0702 0.9998 221125_WJC_METTL3_EV_vs_WT_F10.18727.18727.4 0.000553 10/222 R.SPHPAIQPLQAPQPAVHVQGQEPLTASMLAAAPPQEQK.Q "sp|Q13310|PABP4_HUMAN,tr|A0A7I2V5W9|A0A7I2V5W9_HUMAN,tr|H0YEU6|H0YEU6_HUMAN,tr|B1ANR0|B1ANR0_HUMAN,tr|A0A7I2V4L7|A0A7I2V4L7_HUMAN,tr|A0A7I2V598|A0A7I2V598_HUMAN,tr|A0A7I2V4V6|A0A7I2V4V6_HUMAN,tr|H0Y6X6|H0Y6X6_HUMAN" 8 3962.0473 2.89 147108 18727 4 3962.059458 991.5191 Polyadenylate-binding protein 4 OS=Homo sapiens OX=9606 GN=PABPC4 PE=1 SV=1 5.95 3275.6 - 87594.6 - - - 3.0797 - 1.939 0.467 - 25.2 1 2 0 0.0122 38 0 0 0 3.16E+06 1.09E+06 - - - 3.4805 0.9994 221125_WJC_METTL3_EV_vs_WT_F10.18732.18732.4 5.69E-10 14/156 K.AYHDLC[160.03]DGSANQLQQLQSQLAHQTEQK.E "sp|Q9UPN3|MACF1_HUMAN,tr|H3BQK9|H3BQK9_HUMAN,tr|A0A7P0MQR8|A0A7P0MQR8_HUMAN,tr|E9PNZ4|E9PNZ4_HUMAN,tr|H0Y390|H0Y390_HUMAN,tr|H3BPE1|H3BPE1_HUMAN,tr|A0A669KB84|A0A669KB84_HUMAN,tr|A0A590UJG2|A0A590UJG2_HUMAN,tr|A0A5F9ZGX0|A0A5F9ZGX0_HUMAN" 9 3110.4476 1.86 147110 18732 4 3110.468411 778.6192 "Microtubule-actin cross-linking factor 1, isoforms 1\2\3\5 OS=Homo sapiens OX=9606 GN=MACF1 PE=1 SV=4" 5.21 3276.3 - 127375 - - - 6.6987 - 3.281 0.609 - 92.1 1 2 0 0.0208 27 0 0 0 1.10E+07 5.91E+06 - - - 4.8927 0.9999 221125_WJC_METTL3_EV_vs_WT_F10.18750.18750.4 9.32E-09 13/234 R.EVGGQGAGNTGGLEPVHPASLPDSSLATSAPLC[160.03]C[160.03]TLC[160.03]HER.L sp|Q7Z5L9|I2BP2_HUMAN 1 4101.8943 2.07 147119 18750 4 4101.909586 1026.4808 Interferon regulatory factor 2-binding protein 2 OS=Homo sapiens OX=9606 GN=IRF2BP2 PE=1 SV=2 4.8 3278.7 - 152286 - - - 3.7356 - 2.58 0.609 - 29.6 1 2 0 0.0153 40 0 0 0 6.95E+06 3.36E+06 - - - 4.7961 0.9973 221125_WJC_METTL3_EV_vs_WT_F10.18752.18752.4 0.000636 7/174 K.VDR[166.11]QPSGDSGLAAETSAISQDLEGVPPSK[136.11]K[136.11].M sp|Q4VC05|BCL7A_HUMAN 1 3064.5523 4.02 147120 18752 4 3064.569288 767.1454 B-cell CLL\lymphoma 7 protein family member A OS=Homo sapiens OX=9606 GN=BCL7A PE=1 SV=1 4.44 3279 - 96495.4 - - - 5.5411 - 1.901 0.517 - 13.2 1 2 1 0.017 30 0 0 0 1.13E+07 2.81E+06 - - - 3.9178 0.9999 221125_WJC_METTL3_EV_vs_WT_F10.18765.18765.4 1.17E-06 12/234 R.EVGGQGAGNTGGLEPVHPASLPDSSLATSAPLC[160.03]C[160.03]TLC[160.03]HER[166.11].L sp|Q7Z5L9|I2BP2_HUMAN 1 4111.9025 2.07 147124 18765 4 4111.916099 1028.9829 Interferon regulatory factor 2-binding protein 2 OS=Homo sapiens OX=9606 GN=IRF2BP2 PE=1 SV=2 4.8 3281.2 - 112140 - - - 3.2992 - 2.296 0.581 - 33.7 1 2 0 0.0136 40 0 0 0 6.95E+06 3.36E+06 - - - 4.5192 1 221125_WJC_METTL3_EV_vs_WT_F10.18772.18772.4 6.17E-14 21/156 K.AYHDLC[160.03]DGSANQLQQLQSQLAHQTEQK[136.11].E "sp|Q9UPN3|MACF1_HUMAN,tr|H3BQK9|H3BQK9_HUMAN,tr|A0A7P0MQR8|A0A7P0MQR8_HUMAN,tr|E9PNZ4|E9PNZ4_HUMAN,tr|H0Y390|H0Y390_HUMAN,tr|H3BPE1|H3BPE1_HUMAN,tr|A0A669KB84|A0A669KB84_HUMAN,tr|A0A590UJG2|A0A590UJG2_HUMAN,tr|A0A5F9ZGX0|A0A5F9ZGX0_HUMAN" 9 3118.4618 1.86 147126 18772 4 3118.462976 780.6227 "Microtubule-actin cross-linking factor 1, isoforms 1\2\3\5 OS=Homo sapiens OX=9606 GN=MACF1 PE=1 SV=4" 5.21 3282.1 - 203958 - - - 0.3851 - 4.286 0.735 - 386.6 1 2 0 0.0012 27 0 0 0 1.11E+07 5.96E+06 - - - 6.0785 0.9673 221125_WJC_METTL3_EV_vs_WT_F10.18784.18784.4 0.0247 5/138 K.QREEYQPATPGLGMFVEVKDPEDK.V sp|Q9BVK6|TMED9_HUMAN 1 2762.3221 2.1 147130 18784 4 2762.33232 691.5878 Transmembrane emp24 domain-containing protein 9 OS=Homo sapiens OX=9606 GN=TMED9 PE=1 SV=2 4.36 3284 - 44678.2 - - - 3.6831 - 1.25 0.293 - 15.3 1 2 2 0.0102 24 0 0 0 6.29E+05 2.99E+05 - - - 1.8451 0.9946 221125_WJC_METTL3_EV_vs_WT_F10.18791.18791.4 0.0416 6/132 R.QTTSNLGHLNK[136.11]PSIQALIHGLNR[166.11].H sp|O00487|PSDE_HUMAN 1 2529.3895 0.75 147135 18791 4 2529.398934 633.3546 26S proteasome non-ATPase regulatory subunit 14 OS=Homo sapiens OX=9606 GN=PSMD14 PE=1 SV=1 11 3285 - 61756.4 - - - 3.7404 - 1.398 0.312 - 18.1 1 2 0 0.0095 23 0 0 0 8.58E+06 1.14E+07 - - - 2.0476 0.9993 221125_WJC_METTL3_EV_vs_WT_F10.18801.18801.2 0.0145 20-Aug K.NALESYAFNMK[136.11].S "sp|P0DMV8|HS71A_HUMAN,sp|P34931|HS71L_HUMAN,sp|P0DMV9|HS71B_HUMAN,tr|Q53FA3|Q53FA3_HUMAN,tr|V9GZ37|V9GZ37_HUMAN,tr|A0A0G2JIW1|A0A0G2JIW1_HUMAN" 6 1294.6107 0.62 147141 18801 2 1294.613647 648.3126 Heat shock 70 kDa protein 1A OS=Homo sapiens OX=9606 GN=HSPA1A PE=1 SV=1 6 3286.4 - 77400.8 - - - 2.2586 - 1.911 0.392 - 216.9 1 2 0 0.0029 11 0 0 0 1.62E+06 2.60E+06 - - - 3.6874 1 221125_WJC_METTL3_EV_vs_WT_F10.18805.18805.3 6.84E-11 14/72 R.TSQNSELNNMQDLVEDYKK.K sp|P35908|K22E_HUMAN 1 2255.0376 38.61 147143 18805 3 2255.041319 752.6865 "Keratin, type II cytoskeletal 2 epidermal OS=Homo sapiens OX=9606 GN=KRT2 PE=1 SV=2" 4.32 3287 - 203442 - - - 1.6532 - 2.919 0.66 - 276.3 1 2 0 0.0037 19 0 0 0 3.79E+07 9.81E+05 - - - 8.5291 0.998 221125_WJC_METTL3_EV_vs_WT_F10.18821.18821.2 0.0175 14-Aug R.VDEIIWVK[136.11].T sp|Q86U44|MTA70_HUMAN 1 1008.5735 0.02 147151 18821 2 1008.576076 505.294 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 4.37 3289.3 - 473800 - - - 2.5214 - 1.904 0.251 - 223.7 1 2 0 0.0025 8 0 0 0 1.15E+06 5.71E+07 - - - 2.8362 0.9951 221125_WJC_METTL3_EV_vs_WT_F10.18832.18832.4 0.00693 13/132 R.QTTSNLGHLNKPSIQALIHGLNR.H sp|O00487|PSDE_HUMAN 1 2511.367 0.76 147158 18832 4 2511.37859 628.849 26S proteasome non-ATPase regulatory subunit 14 OS=Homo sapiens OX=9606 GN=PSMD14 PE=1 SV=1 11 3290.8 - 219646 - - - 4.6138 - 2.756 0.325 - 95.5 1 2 0 0.0116 23 0 0 0 8.58E+06 1.13E+07 - - - 2.38 1 221125_WJC_METTL3_EV_vs_WT_F10.18845.18845.3 9.78E-10 14/68 K.DFDFESANAQFNK[136.11]EEIDR[166.11].E "sp|Q8ND56|LS14A_HUMAN,tr|A0A140TA76|A0A140TA76_HUMAN,tr|K7EMZ9|K7EMZ9_HUMAN" 3 2191.9777 1.09 147167 18845 3 2191.980729 731.6665 Protein LSM14 homolog A OS=Homo sapiens OX=9606 GN=LSM14A PE=1 SV=3 4.02 3292.6 - 159024 - - - 1.3764 - 2.677 0.714 - 120.3 1 2 1 0.003 18 0 0 0 6.87E+06 6.31E+06 - - - 8.9516 0.9997 221125_WJC_METTL3_EV_vs_WT_F10.18846.18846.3 5.23E-06 14/68 K.DFDFESANAQFNKEEIDR.E "sp|Q8ND56|LS14A_HUMAN,tr|A0A140TA76|A0A140TA76_HUMAN,tr|K7EMZ9|K7EMZ9_HUMAN" 3 2173.9552 1.09 147168 18846 3 2173.961901 725.659 Protein LSM14 homolog A OS=Homo sapiens OX=9606 GN=LSM14A PE=1 SV=3 4.02 3292.7 - 128438 - - - 3.0631 - 2.759 0.585 - 139.4 1 2 1 0.0067 18 0 0 0 6.87E+06 6.31E+06 - - - 7.5875 0.988 221125_WJC_METTL3_EV_vs_WT_F10.18847.18847.3 0.0391 Jul-76 K.HYFQNTQGLIFVVDSNDRER.L "sp|P18085|ARF4_HUMAN,sp|P84077|ARF1_HUMAN,sp|P61204|ARF3_HUMAN,sp|P84085|ARF5_HUMAN,tr|F5H423|F5H423_HUMAN,tr|C9J1Z8|C9J1Z8_HUMAN,tr|C9JPM4|C9JPM4_HUMAN,tr|C9JAK5|C9JAK5_HUMAN,tr|F5H0C7|F5H0C7_HUMAN" 9 2437.1775 1.36 147169 18847 3 2437.178137 813.3998 ADP-ribosylation factor 4 OS=Homo sapiens OX=9606 GN=ARF4 PE=1 SV=3 5.38 3292.9 - 58414.9 - - - 0.2733 - 1.355 0.302 - 44.4 1 2 1 0.0007 20 0 0 0 1.28E+06 9.45E+05 - - - 2.6438 1 221125_WJC_METTL3_EV_vs_WT_F10.18867.18867.4 1.28E-06 14/126 K.HTDESLGDC[160.03]SFLNTC[160.03]FHMDTC[160.03]K[136.11].Y "sp|Q86U44|MTA70_HUMAN,tr|H0YFV6|H0YFV6_HUMAN" 2 2682.0698 0.22 147178 18867 4 2683.068714 671.5247 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 4.64 3295.8 - 267540 - - - 372.4251 - 3.377 0.682 - 149.7 1 2 0 0.9989 22 0 0 0 4.68E+06 2.16E+07 - - - 5.2836 1 221125_WJC_METTL3_EV_vs_WT_F10.18872.18872.3 3.46E-12 11/132 S.QDAANKNPFSSASGGFGSTATSNTSNLFGNSGAK.T "sp|P35658|NU214_HUMAN,tr|A0A494C0Y1|A0A494C0Y1_HUMAN,tr|A0A0A0MSW3|A0A0A0MSW3_HUMAN,tr|B7ZAV2|B7ZAV2_HUMAN,tr|A0A494C1F2|A0A494C1F2_HUMAN,tr|H0Y837|H0Y837_HUMAN" 6 3291.5028 2.19 147181 18872 3 3291.505108 1098.1749 Nuclear pore complex protein Nup214 OS=Homo sapiens OX=9606 GN=NUP214 PE=1 SV=2 8.59 3296.5 - 176751 - - - 0.6887 - 3.112 0.72 - 65.4 1 1 1 0.0023 34 0 0 0 9.22E+06 4.22E+06 - - - 9.1785 1 221125_WJC_METTL3_EV_vs_WT_F10.18878.18878.4 3.84E-08 15/198 R.SDSPVPTAPTSGGPK[136.11]PSTASAVPELATDPELEK[136.11]K[136.11].L "sp|Q86U44|MTA70_HUMAN,tr|B4E349|B4E349_HUMAN,tr|F5H6D8|F5H6D8_HUMAN,tr|B4DTN4|B4DTN4_HUMAN" 4 3384.7363 0.02 147184 18878 4 3384.740295 847.1913 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 4.51 3297.4 - 639452 - - - 1.1918 - 2.899 0.505 - 74.4 1 2 0 0.004 34 0 0 0 1.14E+06 7.27E+07 - - - 3.9378 1 221125_WJC_METTL3_EV_vs_WT_F10.18880.18880.3 1.56E-09 10/132 S.QDAANK[136.11]NPFSSASGGFGSTATSNTSNLFGNSGAK[136.11].T "sp|P35658|NU214_HUMAN,tr|A0A494C0Y1|A0A494C0Y1_HUMAN,tr|A0A0A0MSW3|A0A0A0MSW3_HUMAN,tr|B7ZAV2|B7ZAV2_HUMAN,tr|A0A494C1F2|A0A494C1F2_HUMAN,tr|H0Y837|H0Y837_HUMAN" 6 3307.5312 2.19 147186 18880 3 3307.530209 1103.5177 Nuclear pore complex protein Nup214 OS=Homo sapiens OX=9606 GN=NUP214 PE=1 SV=2 8.59 3297.6 - 94637.6 - - - -0.312 - 2.661 0.714 - 76.3 1 1 1 -0.001 34 0 0 0 9.22E+06 4.22E+06 - - - 8.7517 1 221125_WJC_METTL3_EV_vs_WT_F10.18883.18883.4 4.07E-16 30/168 S.LNQQGAHSALSSASTSSHNLQSIFNIGSR.G "sp|P43243|MATR3_HUMAN,tr|A8MXP9|A8MXP9_HUMAN,tr|D6R991|D6R991_HUMAN,tr|D6REK4|D6REK4_HUMAN,tr|A0A0R4J2E8|A0A0R4J2E8_HUMAN,tr|D6RCM3|D6RCM3_HUMAN,tr|D6R8Z5|D6R8Z5_HUMAN,tr|D6REM6|D6REM6_HUMAN" 8 3011.4809 1.23 147187 18883 4 3011.484239 753.8775 Matrin-3 OS=Homo sapiens OX=9606 GN=MATR3 PE=1 SV=2 9.76 3298.1 - 639652 - - - 1.1011 - 4.892 0.708 - 472.2 1 1 0 0.0033 29 0 0 0 4.25E+07 3.45E+07 - - - 5.8768 0.9997 221125_WJC_METTL3_EV_vs_WT_F10.18898.18898.2 0.00022 22-Aug R.GYISPYFINTSK[136.11].G "sp|P10809|CH60_HUMAN,tr|A0A7I2V2X6|A0A7I2V2X6_HUMAN,tr|A0A7I2V599|A0A7I2V599_HUMAN,tr|A0A7I2YQ71|A0A7I2YQ71_HUMAN,tr|E7ESH4|E7ESH4_HUMAN,tr|A0A7I2V5M1|A0A7I2V5M1_HUMAN,tr|A0A7I2V5K3|A0A7I2V5K3_HUMAN,tr|A0A7I2V369|A0A7I2V369_HUMAN" 8 1396.7118 2.07 147195 18898 2 1396.713857 699.3632 "60 kDa heat shock protein, mitochondrial OS=Homo sapiens OX=9606 GN=HSPD1 PE=1 SV=2" 8.5 3300.1 - 87002.4 - - - 1.4606 - 1.655 0.507 - 208.1 1 2 0 0.002 12 0 0 0 1.20E+07 5.81E+06 - - - 4.1106 0.9997 221125_WJC_METTL3_EV_vs_WT_F10.18901.18901.2 3.03E-06 22-Oct R.GYISPYFINTSK.G "sp|P10809|CH60_HUMAN,tr|A0A7I2V2X6|A0A7I2V2X6_HUMAN,tr|A0A7I2V599|A0A7I2V599_HUMAN,tr|A0A7I2YQ71|A0A7I2YQ71_HUMAN,tr|E7ESH4|E7ESH4_HUMAN,tr|A0A7I2V5M1|A0A7I2V5M1_HUMAN,tr|A0A7I2V5K3|A0A7I2V5K3_HUMAN,tr|A0A7I2V369|A0A7I2V369_HUMAN" 8 1388.6976 2.09 147196 18901 2 1388.700456 695.3561 "60 kDa heat shock protein, mitochondrial OS=Homo sapiens OX=9606 GN=HSPD1 PE=1 SV=2" 8.5 3300.5 - 239098 - - - 2.0444 - 2.086 0.508 - 379.2 1 2 0 0.0028 12 0 0 0 1.22E+07 5.83E+06 - - - 4.7268 0.9966 221125_WJC_METTL3_EV_vs_WT_F10.18904.18904.3 8.89E-07 9/112 S.LNQQGAHSALSSASTSSHNLQSIFNIGSR.G "sp|P43243|MATR3_HUMAN,tr|A8MXP9|A8MXP9_HUMAN,tr|D6R991|D6R991_HUMAN,tr|D6REK4|D6REK4_HUMAN,tr|A0A0R4J2E8|A0A0R4J2E8_HUMAN,tr|D6RCM3|D6RCM3_HUMAN,tr|D6R8Z5|D6R8Z5_HUMAN,tr|D6REM6|D6REM6_HUMAN" 8 3011.4809 1.24 147199 18904 3 3011.484169 1004.8343 Matrin-3 OS=Homo sapiens OX=9606 GN=MATR3 PE=1 SV=2 9.76 3300.9 - 75571.6 - - - 1.0779 - 1.961 0.581 - 39.1 1 1 0 0.0032 29 0 0 0 1.96E+06 1.58E+06 - - - 6.566 0.9958 221125_WJC_METTL3_EV_vs_WT_F10.18924.18924.4 0.169 6/174 K.QGGQGDGIQVNSQFQQEFPSLQAAGDQEKK.E "sp|Q9Y520|PRC2C_HUMAN,tr|E7EPN9|E7EPN9_HUMAN" 2 3218.5228 0.89 147207 18924 4 3218.523197 805.638 Protein PRRC2C OS=Homo sapiens OX=9606 GN=PRRC2C PE=1 SV=4 4.32 3303.8 - 196104 - - - 0.1084 - 1.437 0.247 - 16.9 1 2 0 0.0003 30 0 0 0 4.06E+06 4.54E+06 - - - 1.4867 1 221125_WJC_METTL3_EV_vs_WT_F10.18936.18936.4 2.12E-20 21/150 K.SNEHDDC[160.03]QVTNPSTGHLFDLSSLSGR.A sp|P11717|MPRI_HUMAN 1 2872.2682 1.52 147212 18936 4 2872.26549 719.0743 Cation-independent mannose-6-phosphate receptor OS=Homo sapiens OX=9606 GN=IGF2R PE=1 SV=3 4.63 3305.4 - 240364 - - - -0.948 - 4.267 0.796 - 302.5 1 2 0 -0.0027 26 0 0 0 2.89E+07 1.90E+07 - - - 6.6113 1 221125_WJC_METTL3_EV_vs_WT_F10.18940.18940.4 2.48E-21 28/150 K.SNEHDDC[160.03]QVTNPSTGHLFDLSSLSGR[166.11].A sp|P11717|MPRI_HUMAN 1 2882.2765 1.52 147213 18940 4 2882.272661 721.5764 Cation-independent mannose-6-phosphate receptor OS=Homo sapiens OX=9606 GN=IGF2R PE=1 SV=3 4.63 3306 - 488236 - - - -1.326 - 4.844 0.822 - 570.5 1 2 0 -0.0038 26 0 0 0 2.89E+07 1.90E+07 - - - 6.8773 0.9549 221125_WJC_METTL3_EV_vs_WT_F10.18970.18970.2 0.774 14-May K.VFLENVIR.D sp|P62805|H4_HUMAN 1 988.5706 1.84 147222 18970 2 988.567879 495.2926 Histone H4 OS=Homo sapiens OX=9606 GN=H4C1 PE=1 SV=2 5.97 3310.4 - 113555 - - - -2.7181 - 1.145 0.136 - 89.6 1 2 0 -0.0027 8 0 0 0 1.47E+07 7.94E+06 - - - 0.453 0.9044 221125_WJC_METTL3_EV_vs_WT_F10.18974.18974.4 3.60E-06 14/168 R.SDSAHQIDEVLHFNEFSQNESKEPDPC[160.03]LK.S sp|Q96P63|SPB12_HUMAN 1 3399.5314 199.39 147224 18974 4 3400.515096 850.8901 Serpin B12 OS=Homo sapiens OX=9606 GN=SERPINB12 PE=1 SV=1 4.43 3310.9 - 844239 - - - 289.3728 - 2.895 0.528 - 61.3 1 2 1 0.9837 29 0 0 0 1.17E+07 5.85E+04 - - - 3.8768 0.9987 221125_WJC_METTL3_EV_vs_WT_F10.18979.18979.2 0.161 14-Jul K.VFLENVIR[166.11].D sp|P62805|H4_HUMAN 1 998.5788 1.84 147226 18979 2 998.577578 500.2967 Histone H4 OS=Homo sapiens OX=9606 GN=H4C1 PE=1 SV=2 5.97 3311.5 - 186132 - - - -1.2598 - 1.474 0.296 - 200.8 1 2 0 -0.0013 8 0 0 0 1.47E+07 7.94E+06 - - - 2.397 0.9983 221125_WJC_METTL3_EV_vs_WT_F10.18982.18982.2 0.766 14-Jul R.ILELDQFK[136.11].G "sp|P12956|XRCC6_HUMAN,tr|B1AHC9|B1AHC9_HUMAN" 2 1012.5684 0.32 147228 18982 2 1012.56614 507.2915 X-ray repair cross-complementing protein 6 OS=Homo sapiens OX=9606 GN=XRCC6 PE=1 SV=2 4.37 3311.8 - 150186 - - - -2.2784 - 1.562 0.323 - 104.8 1 2 0 -0.0023 8 0 0 0 1.69E+06 5.25E+06 - - - 2.771 0.9999 221125_WJC_METTL3_EV_vs_WT_F10.18986.18986.4 1.23E-07 15/156 K.GEWIK[136.11]PGAIVIDC[160.03]GINYVPDDK[136.11]K[136.11]PNGR[166.11].K "sp|P11586|C1TC_HUMAN,tr|F5H2F4|F5H2F4_HUMAN,tr|V9GZ78|V9GZ78_HUMAN,tr|V9GYY3|V9GYY3_HUMAN" 4 3044.5843 2.49 147229 18986 4 3044.582267 762.1534 "C-1-tetrahydrofolate synthase, cytoplasmic OS=Homo sapiens OX=9606 GN=MTHFD1 PE=1 SV=4" 6.15 3312.4 - 127363 - - - -0.6832 - 3.112 0.609 - 115.6 1 2 1 -0.0021 27 0 0 0 7.69E+06 3.09E+06 - - - 4.8814 1 221125_WJC_METTL3_EV_vs_WT_F10.18995.18995.4 4.79E-11 18/150 A.DEHEHTYQDK[136.11]EEVVLWMNTVGPYHNR[166.11].Q sp|Q9HD45|TM9S3_HUMAN 1 3243.4799 1.64 147234 18995 4 3243.471118 811.8772 Transmembrane 9 superfamily member 3 OS=Homo sapiens OX=9606 GN=TM9SF3 PE=1 SV=2 4.94 3313.6 - 154028 - - - -2.7017 - 3.541 0.684 - 140.9 1 1 1 -0.0088 26 0 0 0 8.27E+06 5.05E+06 - - - 5.5759 1 221125_WJC_METTL3_EV_vs_WT_F10.18996.18996.4 2.15E-05 22/150 A.DEHEHTYQDKEEVVLWMNTVGPYHNR.Q sp|Q9HD45|TM9S3_HUMAN 1 3225.4574 1.62 147235 18996 4 3225.452705 807.3716 Transmembrane 9 superfamily member 3 OS=Homo sapiens OX=9606 GN=TM9SF3 PE=1 SV=2 4.94 3313.7 - 220627 - - - -1.459 - 4.296 0.674 - 261.6 1 1 1 -0.0047 26 0 0 0 8.15E+06 5.03E+06 - - - 5.551 1 221125_WJC_METTL3_EV_vs_WT_F10.19008.19008.3 1.09E-14 22/84 K.HTDESLGDC[160.03]SFLNTC[160.03]FHMDTC[160.03]K[136.11].Y "sp|Q86U44|MTA70_HUMAN,tr|H0YFV6|H0YFV6_HUMAN" 2 2682.0698 0.01 147242 19008 3 2683.074496 895.0306 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 4.64 3315.6 - 316918 - - - 374.5808 - 4.819 0.764 - 699.6 1 2 0 1.0047 22 0 0 0 2.35E+06 2.76E+08 - - - 10.5079 1 221125_WJC_METTL3_EV_vs_WT_F10.19017.19017.4 2.54E-10 19/156 K.GEWIKPGAIVIDC[160.03]GINYVPDDKKPNGR.K "sp|P11586|C1TC_HUMAN,tr|F5H2F4|F5H2F4_HUMAN,tr|V9GZ78|V9GZ78_HUMAN,tr|V9GYY3|V9GYY3_HUMAN" 4 3010.5335 2.5 147246 19017 4 3010.546951 753.6406 "C-1-tetrahydrofolate synthase, cytoplasmic OS=Homo sapiens OX=9606 GN=MTHFD1 PE=1 SV=4" 6.15 3316.8 - 143362 - - - 4.4756 - 3.597 0.692 - 190.1 1 2 1 0.0135 27 0 0 0 7.73E+06 3.09E+06 - - - 5.646 1 221125_WJC_METTL3_EV_vs_WT_F10.19018.19018.4 1.66E-11 14/156 K.FC[160.03]KYEHDDIVSTVSVLSSGTQAVSGSK.D "sp|Q9BQA1|MEP50_HUMAN,tr|H0Y711|H0Y711_HUMAN" 2 2900.3862 3.72 147247 19018 4 2900.400682 726.1038 Methylosome protein 50 OS=Homo sapiens OX=9606 GN=WDR77 PE=1 SV=1 5.38 3316.9 - 63338.1 - - - 4.9921 - 3.083 0.644 - 144.2 1 2 1 0.0145 27 0 0 0 2.53E+06 6.80E+05 - - - 5.1797 0.9923 221125_WJC_METTL3_EV_vs_WT_F10.19047.19047.4 1.72E-09 18/204 R.SNGTNTSAPQDIYAVNGIAFHPVHGTLATVGSDGR.F "sp|P78406|RAE1L_HUMAN,tr|E9PQ57|E9PQ57_HUMAN" 2 3523.708 1.87 147264 19047 4 3524.694077 881.9343 mRNA export factor OS=Homo sapiens OX=9606 GN=RAE1 PE=1 SV=1 5.93 3321.2 - 272124 - - - 279.8342 - 3.278 0.591 - 109.2 1 2 0 0.9861 35 0 0 0 7.08E+06 3.79E+06 - - - 4.4489 0.9945 221125_WJC_METTL3_EV_vs_WT_F10.19050.19050.3 0.0236 Sep-80 K.NVQDAIADAEQRGEHALKDAR.N sp|P35908|K22E_HUMAN 1 2306.1363 123.9 147267 19050 3 2306.146542 769.7194 "Keratin, type II cytoskeletal 2 epidermal OS=Homo sapiens OX=9606 GN=KRT2 PE=1 SV=2" 4.83 3321.6 - 57879.1 - - - 4.4265 - 2.031 0.437 - 77.1 1 2 2 0.0102 21 0 0 0 5.14E+06 4.15E+04 - - - 5.108 0.9999 221125_WJC_METTL3_EV_vs_WT_F10.19057.19057.4 8.73E-09 17/138 K.C[160.03]NEIINWLDK[136.11]NQTAEK[136.11]EEFEHQQK[136.11].E "sp|P11142|HSP7C_HUMAN,tr|E9PNE6|E9PNE6_HUMAN,tr|A8K7Q2|A8K7Q2_HUMAN,tr|E9PKE3|E9PKE3_HUMAN,tr|E9PM13|E9PM13_HUMAN,tr|E9PS65|E9PS65_HUMAN" 6 3054.4567 0.05 147270 19057 4 3054.460637 764.6215 Heat shock cognate 71 kDa protein OS=Homo sapiens OX=9606 GN=HSPA8 PE=1 SV=1 4.7 3322.6 - 190788 - - - 1.2729 - 3.579 0.573 - 197 1 2 2 0.0039 24 0 0 0 3.24E+06 6.24E+07 - - - 4.6216 1 221125_WJC_METTL3_EV_vs_WT_F10.19059.19059.4 3.85E-11 22/204 R.SNGTNTSAPQDIYAVNGIAFHPVHGTLATVGSDGR[166.11].F "sp|P78406|RAE1L_HUMAN,tr|E9PQ57|E9PQ57_HUMAN" 2 3533.7163 1.89 147272 19059 4 3534.706782 884.4363 mRNA export factor OS=Homo sapiens OX=9606 GN=RAE1 PE=1 SV=1 5.93 3322.9 - 274719 - - - 280.2967 - 3.807 0.672 - 150.6 1 2 0 0.9905 35 0 0 0 7.08E+06 3.75E+06 - - - 5.197 0.9989 221125_WJC_METTL3_EV_vs_WT_F10.19080.19080.3 0.000765 5/136 K.VGLPSPSSLVPGSSSQLSGNGNSGTSGPSGSTTSK.T "sp|Q96CB8|INT12_HUMAN,tr|A0A087WXN4|A0A087WXN4_HUMAN" 2 3174.5277 0.93 147284 19080 3 3174.538833 1059.1832 Integrator complex subunit 12 OS=Homo sapiens OX=9606 GN=INTS12 PE=1 SV=1 8.72 3325.9 - 52771.7 - - - 3.5199 - 1.478 0.462 - 14.1 1 2 0 0.0112 35 0 0 0 2.76E+07 2.96E+07 - - - 4.5866 0.9998 221125_WJC_METTL3_EV_vs_WT_F10.19081.19081.3 3.76E-05 6/136 K.VGLPSPSSLVPGSSSQLSGNGNSGTSGPSGSTTSK[136.11].T "sp|Q96CB8|INT12_HUMAN,tr|A0A087WXN4|A0A087WXN4_HUMAN" 2 3182.5419 0.94 147285 19081 3 3182.536339 1061.8546 Integrator complex subunit 12 OS=Homo sapiens OX=9606 GN=INTS12 PE=1 SV=1 8.72 3326 - 58980.2 - - - -1.7345 - 1.412 0.485 - 21.8 1 2 0 -0.0055 35 0 0 0 2.86E+07 3.05E+07 - - - 4.7395 0.9728 221125_WJC_METTL3_EV_vs_WT_F10.19086.19086.3 0.000282 Sep-44 R.ARFEELNADLFR.G "sp|P54652|HSP72_HUMAN,sp|P11142|HSP7C_HUMAN,tr|E9PNE6|E9PNE6_HUMAN,tr|A8K7Q2|A8K7Q2_HUMAN,tr|E9PKE3|E9PKE3_HUMAN,tr|E9PN89|E9PN89_HUMAN" 6 1479.747 0.17 147288 19086 3 1479.759405 494.2563 Heat shock-related 70 kDa protein 2 OS=Homo sapiens OX=9606 GN=HSPA2 PE=1 SV=1 4.68 3326.7 - 58277.9 - - - 8.3649 - 1.829 0.49 - 152.8 1 2 1 0.0124 12 0 0 0 2.36E+06 1.40E+07 - - - 5.6731 0.9999 221125_WJC_METTL3_EV_vs_WT_F10.19089.19089.4 3.92E-09 18/138 K.C[160.03]NEIINWLDKNQTAEKEEFEHQQK.E "sp|P11142|HSP7C_HUMAN,tr|E9PNE6|E9PNE6_HUMAN,tr|A8K7Q2|A8K7Q2_HUMAN,tr|E9PKE3|E9PKE3_HUMAN,tr|E9PM13|E9PM13_HUMAN,tr|E9PS65|E9PS65_HUMAN" 6 3030.4141 0.05 147290 19089 4 3030.414961 758.6108 Heat shock cognate 71 kDa protein OS=Homo sapiens OX=9606 GN=HSPA8 PE=1 SV=1 4.7 3327.1 - 157457 - - - 0.268 - 3.386 0.595 - 221.3 1 2 2 0.0008 24 0 0 0 3.24E+06 6.09E+07 - - - 4.7961 0.9999 221125_WJC_METTL3_EV_vs_WT_F10.19091.19091.4 2.83E-07 13/138 K.KDTSNHFHVFVGDLSPEITTEDIK.S "sp|Q01085|TIAR_HUMAN,tr|C9JTN7|C9JTN7_HUMAN,tr|E7ETC0|E7ETC0_HUMAN,tr|H7BY49|H7BY49_HUMAN,tr|A6NKZ9|A6NKZ9_HUMAN,tr|E7ETJ9|E7ETJ9_HUMAN" 6 2728.3344 1.85 147292 19091 4 2728.34339 683.0909 Nucleolysin TIAR OS=Homo sapiens OX=9606 GN=TIAL1 PE=1 SV=1 4.8 3327.3 - 108549 - - - 3.2859 - 2.735 0.544 - 111.6 1 2 0 0.009 24 0 0 0 2.91E+06 1.58E+06 - - - 4.2814 0.9763 221125_WJC_METTL3_EV_vs_WT_F10.19094.19094.4 0.00407 5/180 S.SSLNQQGAHSALSSASTSSHNLQSIFNIGSR.G "sp|P43243|MATR3_HUMAN,tr|A8MXP9|A8MXP9_HUMAN,tr|D6R991|D6R991_HUMAN,tr|D6REK4|D6REK4_HUMAN,tr|A0A0R4J2E8|A0A0R4J2E8_HUMAN,tr|D6RCM3|D6RCM3_HUMAN,tr|D6R8Z5|D6R8Z5_HUMAN,tr|D6REM6|D6REM6_HUMAN" 8 3185.545 1.3 147293 19094 4 3185.551198 797.3935 Matrin-3 OS=Homo sapiens OX=9606 GN=MATR3 PE=1 SV=2 9.51 3327.8 - 59361.6 - - - 1.9519 - 1.378 0.426 - 11.3 1 1 0 0.0062 31 0 0 0 2.10E+08 1.62E+08 - - - 3.0296 0.994 221125_WJC_METTL3_EV_vs_WT_F10.19096.19096.4 6.47E-08 14/186 M.SSSLNQQGAHSALSSASTSSHNLQSIFNIGSR[166.11].G "sp|P43243|MATR3_HUMAN,tr|A8MXP9|A8MXP9_HUMAN,tr|D6R991|D6R991_HUMAN,tr|D6REK4|D6REK4_HUMAN,tr|A0A0R4J2E8|A0A0R4J2E8_HUMAN,tr|D6RCM3|D6RCM3_HUMAN,tr|D6R8Z5|D6R8Z5_HUMAN,tr|D6REM6|D6REM6_HUMAN" 8 3282.5853 1.36 147295 19096 4 3282.595358 821.6536 Matrin-3 OS=Homo sapiens OX=9606 GN=MATR3 PE=1 SV=2 9.51 3328 - 182150 - - - 3.0704 - 2.762 0.601 - 99.8 1 1 0 0.0101 32 0 0 0 6.91E+07 5.08E+07 - - - 4.7611 1 221125_WJC_METTL3_EV_vs_WT_F10.19100.19100.4 2.30E-08 16/198 R.SDSPVPTAPTSGGPK[136.11]PSTASAVPELATDPELEK[136.11]K[136.11].L "sp|Q86U44|MTA70_HUMAN,tr|B4E349|B4E349_HUMAN,tr|F5H6D8|F5H6D8_HUMAN,tr|B4DTN4|B4DTN4_HUMAN" 4 3384.7363 0 147297 19100 4 3384.741443 847.1913 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 4.51 3328.6 - 502092 - - - 1.531 - 3.176 0.535 - 112.5 1 2 0 0.0052 34 0 0 0 2.19E+05 5.22E+07 - - - 4.2258 0.9997 221125_WJC_METTL3_EV_vs_WT_F10.19101.19101.3 4.75E-07 Dec-44 R.AR[166.11]FEELNADLFR[166.11].G "sp|P54652|HSP72_HUMAN,sp|P11142|HSP7C_HUMAN,tr|E9PNE6|E9PNE6_HUMAN,tr|A8K7Q2|A8K7Q2_HUMAN,tr|E9PKE3|E9PKE3_HUMAN,tr|E9PN89|E9PN89_HUMAN" 6 1499.7636 0.17 147298 19101 3 1499.768312 500.9285 Heat shock-related 70 kDa protein 2 OS=Homo sapiens OX=9606 GN=HSPA2 PE=1 SV=1 4.68 3328.7 - 425488 - - - 3.1638 - 2.63 0.545 - 335 1 2 1 0.0047 12 0 0 0 2.48E+06 1.47E+07 - - - 7.2952 1 221125_WJC_METTL3_EV_vs_WT_F10.19102.19102.4 3.51E-15 30/186 M.SSSLNQQGAHSALSSASTSSHNLQSIFNIGSR.G "sp|P43243|MATR3_HUMAN,tr|A8MXP9|A8MXP9_HUMAN,tr|D6R991|D6R991_HUMAN,tr|D6REK4|D6REK4_HUMAN,tr|A0A0R4J2E8|A0A0R4J2E8_HUMAN,tr|D6RCM3|D6RCM3_HUMAN,tr|D6R8Z5|D6R8Z5_HUMAN,tr|D6REM6|D6REM6_HUMAN" 8 3272.577 1.36 147299 19102 4 3272.585298 819.1515 Matrin-3 OS=Homo sapiens OX=9606 GN=MATR3 PE=1 SV=2 9.51 3328.9 - 332927 - - - 2.5329 - 4.931 0.744 - 547.5 1 1 0 0.0083 32 0 0 0 6.91E+07 5.08E+07 - - - 6.1812 1 221125_WJC_METTL3_EV_vs_WT_F10.19112.19112.4 1.07E-14 26/180 S.SSLNQQGAHSALSSASTSSHNLQSIFNIGSR[166.11].G "sp|P43243|MATR3_HUMAN,tr|A8MXP9|A8MXP9_HUMAN,tr|D6R991|D6R991_HUMAN,tr|D6REK4|D6REK4_HUMAN,tr|A0A0R4J2E8|A0A0R4J2E8_HUMAN,tr|D6RCM3|D6RCM3_HUMAN,tr|D6R8Z5|D6R8Z5_HUMAN,tr|D6REM6|D6REM6_HUMAN" 8 3195.5532 1.3 147304 19112 4 3195.550053 799.8956 Matrin-3 OS=Homo sapiens OX=9606 GN=MATR3 PE=1 SV=2 9.51 3330.1 - 505830 - - - -1.0005 - 4.259 0.668 - 333.4 1 1 0 -0.0032 31 0 0 0 2.10E+08 1.62E+08 - - - 5.4798 0.9963 221125_WJC_METTL3_EV_vs_WT_F10.19130.19130.4 2.43E-09 14/174 S.SLNQQGAHSALSSASTSSHNLQSIFNIGSR.G "sp|P43243|MATR3_HUMAN,tr|A8MXP9|A8MXP9_HUMAN,tr|D6R991|D6R991_HUMAN,tr|D6REK4|D6REK4_HUMAN,tr|A0A0R4J2E8|A0A0R4J2E8_HUMAN,tr|D6RCM3|D6RCM3_HUMAN,tr|D6R8Z5|D6R8Z5_HUMAN,tr|D6REM6|D6REM6_HUMAN" 8 3098.513 1.2 147312 19130 4 3098.519992 775.6355 Matrin-3 OS=Homo sapiens OX=9606 GN=MATR3 PE=1 SV=2 9.51 3332.9 - 165531 - - - 2.2721 - 2.941 0.588 - 102.3 1 1 0 0.007 30 0 0 0 2.08E+07 1.74E+07 - - - 4.6721 0.9971 221125_WJC_METTL3_EV_vs_WT_F10.19136.19136.4 0.000257 12/174 S.SLNQQGAHSALSSASTSSHNLQSIFNIGSR[166.11].G "sp|P43243|MATR3_HUMAN,tr|A8MXP9|A8MXP9_HUMAN,tr|D6R991|D6R991_HUMAN,tr|D6REK4|D6REK4_HUMAN,tr|A0A0R4J2E8|A0A0R4J2E8_HUMAN,tr|D6RCM3|D6RCM3_HUMAN,tr|D6R8Z5|D6R8Z5_HUMAN,tr|D6REM6|D6REM6_HUMAN" 8 3108.5212 1.2 147316 19136 4 3108.52269 778.1376 Matrin-3 OS=Homo sapiens OX=9606 GN=MATR3 PE=1 SV=2 9.51 3333.7 - 185083 - - - 0.4723 - 2.632 0.542 - 71.3 1 1 0 0.0015 30 0 0 0 2.08E+07 1.74E+07 - - - 4.2393 0.9982 221125_WJC_METTL3_EV_vs_WT_F10.19140.19140.3 2.74E-08 14/120 S.SSLNQQGAHSALSSASTSSHNLQSIFNIGSR[166.11].G "sp|P43243|MATR3_HUMAN,tr|A8MXP9|A8MXP9_HUMAN,tr|D6R991|D6R991_HUMAN,tr|D6REK4|D6REK4_HUMAN,tr|A0A0R4J2E8|A0A0R4J2E8_HUMAN,tr|D6RCM3|D6RCM3_HUMAN,tr|D6R8Z5|D6R8Z5_HUMAN,tr|D6REM6|D6REM6_HUMAN" 8 3195.5532 3.31 147318 19140 3 3195.556845 1066.1917 Matrin-3 OS=Homo sapiens OX=9606 GN=MATR3 PE=1 SV=2 9.51 3334.2 - 134397 - - - 1.125 - 2.299 0.634 - 86.4 1 1 0 0.0036 31 0 0 0 2.92E+07 8.82E+06 - - - 7.5227 0.9986 221125_WJC_METTL3_EV_vs_WT_F10.19177.19177.3 0.0028 Nov-52 R.NKLNDLEEALQQAK.E sp|P35908|K22E_HUMAN 1 1612.842 999 147332 19177 3 1612.83971 538.6213 "Keratin, type II cytoskeletal 2 epidermal OS=Homo sapiens OX=9606 GN=KRT2 PE=1 SV=2" 4.68 3339.6 - 217721 - - - -1.4509 - 1.989 0.361 - 64.4 1 2 1 -0.0023 14 0 0 0 7.93E+06 0.00E+00 - - - 4.3915 1 221125_WJC_METTL3_EV_vs_WT_F10.19193.19193.4 6.31E-12 20/162 R.KQQNVDQAVATLQGEGLSVTGTVC[160.03]HVGK.A "sp|Q6PKH6|DR4L2_HUMAN,sp|Q9BTZ2|DHRS4_HUMAN,tr|F5GWZ1|F5GWZ1_HUMAN,tr|F6TD35|F6TD35_HUMAN,tr|E9PFL3|E9PFL3_HUMAN,tr|A0A087WXI8|A0A087WXI8_HUMAN" 6 2923.4822 1.33 147340 19193 4 2923.477683 731.8778 Dehydrogenase\reductase SDR family member 4-like 2 OS=Homo sapiens OX=9606 GN=DHRS4L2 PE=2 SV=2 6.74 3341.7 - 227983 - - - -1.5345 - 4.086 0.669 - 231.3 1 2 0 -0.0045 28 0 0 0 1.33E+07 1.00E+07 - - - 5.4848 1 221125_WJC_METTL3_EV_vs_WT_F10.19194.19194.4 1.11E-14 23/162 R.K[136.11]QQNVDQAVATLQGEGLSVTGTVC[160.03]HVGK[136.11].A "sp|Q6PKH6|DR4L2_HUMAN,sp|Q9BTZ2|DHRS4_HUMAN,tr|F5GWZ1|F5GWZ1_HUMAN,tr|F6TD35|F6TD35_HUMAN,tr|E9PFL3|E9PFL3_HUMAN,tr|A0A087WXI8|A0A087WXI8_HUMAN" 6 2939.5106 1.33 147341 19194 4 2939.506508 735.8849 Dehydrogenase\reductase SDR family member 4-like 2 OS=Homo sapiens OX=9606 GN=DHRS4L2 PE=2 SV=2 6.74 3341.9 - 202486 - - - -1.3815 - 4.736 0.652 - 340.9 1 2 0 -0.0041 28 0 0 0 1.33E+07 1.00E+07 - - - 5.3827 0.9997 221125_WJC_METTL3_EV_vs_WT_F10.19200.19200.3 1.08E-06 Oct-64 K.MLQAPESVLAEHYQDLR.R "sp|O00746|NDKM_HUMAN,tr|Q4TT34|Q4TT34_HUMAN,tr|H0Y6J0|H0Y6J0_HUMAN,tr|F2Z2X0|F2Z2X0_HUMAN,tr|A2IDC9|A2IDC9_HUMAN" 5 1998.9833 3.73 147344 19200 3 1998.991667 667.335 "Nucleoside diphosphate kinase, mitochondrial OS=Homo sapiens OX=9606 GN=NME4 PE=1 SV=1" 4.65 3342.6 - 90668.7 - - - 4.1801 - 2.037 0.532 - 108.1 1 2 0 0.0084 17 0 0 0 3.37E+06 9.04E+05 - - - 6.2664 1 221125_WJC_METTL3_EV_vs_WT_F10.19206.19206.4 1.24E-07 17/126 R.SDSAHQIDEVLHFNEFSQNESK.E sp|Q96P63|SPB12_HUMAN 1 2560.1466 100.2 147346 19206 4 2560.145346 641.0439 Serpin B12 OS=Homo sapiens OX=9606 GN=SERPINB12 PE=1 SV=1 4.49 3343.4 - 223048 - - - -0.4992 - 2.947 0.625 - 211.2 1 2 0 -0.0013 22 0 0 0 6.27E+06 6.26E+04 - - - 5.0193 0.9999 221125_WJC_METTL3_EV_vs_WT_F10.19225.19225.3 3.22E-06 13/48 R.KIEEIKDFLLTAR.R "sp|P63173|RL38_HUMAN,tr|J3KT73|J3KT73_HUMAN,tr|J3QL01|J3QL01_HUMAN,tr|J3KSP2|J3KSP2_HUMAN" 4 1574.9032 1.11 147355 19225 3 1574.905096 525.975 60S ribosomal protein L38 OS=Homo sapiens OX=9606 GN=RPL38 PE=1 SV=2 6.18 3346.1 - 134808 - - - 1.2077 - 2.706 0.603 - 240.7 1 2 1 0.0019 13 0 0 0 4.08E+07 3.68E+07 - - - 7.9613 0.9999 221125_WJC_METTL3_EV_vs_WT_F10.19229.19229.3 0.000212 16/48 R.K[136.11]IEEIK[136.11]DFLLTAR[166.11].R "sp|P63173|RL38_HUMAN,tr|J3KT73|J3KT73_HUMAN,tr|J3QL01|J3QL01_HUMAN,tr|J3KSP2|J3KSP2_HUMAN" 4 1600.9399 1.11 147357 19229 3 1600.94292 534.6539 60S ribosomal protein L38 OS=Homo sapiens OX=9606 GN=RPL38 PE=1 SV=2 6.18 3346.7 - 310118 - - - 1.9095 - 2.757 0.558 - 338.7 1 2 1 0.0031 13 0 0 0 4.08E+07 3.68E+07 - - - 7.5099 0.9996 221125_WJC_METTL3_EV_vs_WT_F10.19238.19238.4 3.62E-05 Dec-72 R.K[136.11]IEEIK[136.11]DFLLTAR[166.11].R "sp|P63173|RL38_HUMAN,tr|J3KT73|J3KT73_HUMAN,tr|J3QL01|J3QL01_HUMAN,tr|J3KSP2|J3KSP2_HUMAN" 4 1600.9399 1.05 147364 19238 4 1600.942325 401.2422 60S ribosomal protein L38 OS=Homo sapiens OX=9606 GN=RPL38 PE=1 SV=2 6.18 3347.9 - 131343 - - - 1.5378 - 2.157 0.436 - 140.2 1 2 1 0.0025 13 0 0 0 8.61E+06 8.21E+06 - - - 3.3053 1 221125_WJC_METTL3_EV_vs_WT_F10.19245.19245.4 2.28E-07 11/168 K.NQSQGYNQWQQGQFWGQK[136.11]PWSQHYHQGYY.- "sp|Q00839|HNRPU_HUMAN,tr|A0A1W2PPL4|A0A1W2PPL4_HUMAN,tr|Q5RI18|Q5RI18_HUMAN,tr|A0A1W2PP35|A0A1W2PP35_HUMAN,tr|A0A1W2PPH7|A0A1W2PPH7_HUMAN,tr|A0A1X7SBS1|A0A1X7SBS1_HUMAN" 6 3665.6129 0.92 147369 19245 4 3665.614596 917.4105 Heterogeneous nuclear ribonucleoprotein U OS=Homo sapiens OX=9606 GN=HNRNPU PE=1 SV=6 8.39 3348.8 - 220937 - - - 0.4499 - 2.645 0.593 - 53.6 1 2 0 0.0016 29 0 0 0 1.67E+07 1.82E+07 - - - 4.6868 1 221125_WJC_METTL3_EV_vs_WT_F10.19250.19250.4 3.19E-08 13/168 K.NQSQGYNQWQQGQFWGQKPWSQHYHQGYY.- "sp|Q00839|HNRPU_HUMAN,tr|A0A1W2PPL4|A0A1W2PPL4_HUMAN,tr|Q5RI18|Q5RI18_HUMAN,tr|A0A1W2PP35|A0A1W2PP35_HUMAN,tr|A0A1W2PPH7|A0A1W2PPH7_HUMAN,tr|A0A1X7SBS1|A0A1X7SBS1_HUMAN" 6 3657.5987 0.92 147372 19250 4 3657.601161 915.407 Heterogeneous nuclear ribonucleoprotein U OS=Homo sapiens OX=9606 GN=HNRNPU PE=1 SV=6 8.39 3349.5 - 230472 - - - 0.66 - 2.813 0.687 - 73.1 1 2 0 0.0024 29 0 0 0 1.67E+07 1.82E+07 - - - 5.5237 0.9999 221125_WJC_METTL3_EV_vs_WT_F10.19263.19263.3 0.000419 Aug-80 R.K[136.11]HAASDVDLEIESLLNQQSTK[136.11].E "sp|Q86U44|MTA70_HUMAN,tr|F5H6D8|F5H6D8_HUMAN,tr|H0YFV6|H0YFV6_HUMAN,tr|B4DTN4|B4DTN4_HUMAN" 4 2341.2096 0.001 147379 19263 3 2341.211044 781.4105 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 4.75 3351.4 - 120301 - - - 0.6087 - 2.108 0.411 - 78.5 1 2 0 0.0014 21 0 0 0 0.00E+00 2.83E+06 - - - 4.9097 0.999 221125_WJC_METTL3_EV_vs_WT_F10.19272.19272.4 0.00456 Dec-72 R.KIEEIKDFLLTAR.R "sp|P63173|RL38_HUMAN,tr|J3KT73|J3KT73_HUMAN,tr|J3QL01|J3QL01_HUMAN,tr|J3KSP2|J3KSP2_HUMAN" 4 1574.9032 1.05 147386 19272 4 1574.903714 394.7331 60S ribosomal protein L38 OS=Homo sapiens OX=9606 GN=RPL38 PE=1 SV=2 6.18 3352.6 - 286215 - - - 0.3302 - 2.1 0.367 - 74.1 1 2 1 0.0005 13 0 0 0 8.61E+06 8.21E+06 - - - 2.6953 0.9995 221125_WJC_METTL3_EV_vs_WT_F10.19290.19290.4 0.00396 6/204 R.SNGTNTSAPQDIYAVNGIAFHPVHGTLATVGSDGR.F "sp|P78406|RAE1L_HUMAN,tr|E9PQ57|E9PQ57_HUMAN" 2 3523.708 2.16 147394 19290 4 3523.697665 881.9343 mRNA export factor OS=Homo sapiens OX=9606 GN=RAE1 PE=1 SV=1 5.93 3355 - 165093 - - - -2.9395 - 1.569 0.409 - 13.6 1 2 0 -0.0104 35 0 0 0 2.31E+06 1.07E+06 - - - 2.9166 0.9825 221125_WJC_METTL3_EV_vs_WT_F10.19296.19296.3 0.309 Jun-36 R.K[136.11]QDSGHLDLR[166.11].N "sp|Q86U44|MTA70_HUMAN,tr|B4E349|B4E349_HUMAN,tr|F5H6D8|F5H6D8_HUMAN,tr|B4DTN4|B4DTN4_HUMAN" 4 1185.6221 0.03 147397 19296 3 1185.62243 396.2146 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 6.75 3355.9 - 72642.2 - - - 0.2741 - 1.055 0.249 - 54.8 1 2 0 0.0003 10 0 0 0 3.79E+04 1.48E+06 - - - 1.4724 0.9383 221125_WJC_METTL3_EV_vs_WT_F10.19300.19300.4 0.398 8/216 K.GSESATYVPVAPPTPAWQPEIKPEPAWHDQDETSSVK.S "sp|Q6PKG0|LARP1_HUMAN,tr|A0A0B4J210|A0A0B4J210_HUMAN,tr|E5RH50|E5RH50_HUMAN,tr|H0YAN4|H0YAN4_HUMAN" 4 4030.9225 1.32 147399 19300 4 4030.928753 1008.7379 La-related protein 1 OS=Homo sapiens OX=9606 GN=LARP1 PE=1 SV=2 4.35 3356.4 - 169685 - - - 1.5532 - 1.466 0.146 - 14.1 1 2 0 0.0063 37 0 0 0 4.76E+06 3.59E+06 - - - 0.6072 0.9998 221125_WJC_METTL3_EV_vs_WT_F10.19301.19301.4 0.000258 9/108 K.ER[166.11]VEAVNMAEGIIHDTETK[136.11].M "sp|P38646|GRP75_HUMAN,tr|A0A7I2V2S7|A0A7I2V2S7_HUMAN,tr|A0A7I2V2G2|A0A7I2V2G2_HUMAN,tr|A0A7I2V3F7|A0A7I2V3F7_HUMAN,tr|A0A7I2YQB2|A0A7I2YQB2_HUMAN,tr|D6RCD7|D6RCD7_HUMAN" 6 2159.0648 0.46 147400 19301 4 2159.067309 540.7735 "Stress-70 protein, mitochondrial OS=Homo sapiens OX=9606 GN=HSPA9 PE=1 SV=2" 4.57 3356.6 - 67939.1 - - - 1.1838 - 1.848 0.49 - 61.5 1 2 1 0.0026 19 0 0 0 9.17E+05 1.99E+06 - - - 3.698 1 221125_WJC_METTL3_EV_vs_WT_F10.19302.19302.4 1.32E-14 29/240 R.TQQTPAAAASGPTPTQPVLPSLALKPTPGGSQPLPTPAQSR.N "sp|Q8IXK0|PHC2_HUMAN,tr|A0A0A0MSI2|A0A0A0MSI2_HUMAN" 2 4016.1331 2.06 147401 19302 4 4016.139779 1005.0405 Polyhomeotic-like protein 2 OS=Homo sapiens OX=9606 GN=PHC2 PE=1 SV=1 11 3356.7 - 297590 - - - 1.6645 - 4.387 0.74 - 234.6 1 2 0 0.0067 41 0 0 0 7.47E+07 3.63E+07 - - - 6.0899 0.9997 221125_WJC_METTL3_EV_vs_WT_F10.19304.19304.3 3.98E-06 Aug-52 K.C[160.03]EFQDAYVLLSEKK.L "sp|P10809|CH60_HUMAN,tr|A0A7I2V2X6|A0A7I2V2X6_HUMAN,tr|A0A7I2YQK6|A0A7I2YQK6_HUMAN,tr|A0A7I2V599|A0A7I2V599_HUMAN,tr|A0A7I2YQ71|A0A7I2YQ71_HUMAN,tr|A0A7I2V5M1|A0A7I2V5M1_HUMAN,tr|A0A7I2V5K3|A0A7I2V5K3_HUMAN,tr|A0A7I2V369|A0A7I2V369_HUMAN" 8 1728.8393 1.53 147403 19304 3 1728.845432 577.287 "60 kDa heat shock protein, mitochondrial OS=Homo sapiens OX=9606 GN=HSPD1 PE=1 SV=2" 4.68 3357 - 69517.1 - - - 3.5625 - 1.529 0.554 - 69.3 1 2 0 0.0062 14 0 0 0 2.28E+06 1.48E+06 - - - 5.8433 0.9997 221125_WJC_METTL3_EV_vs_WT_F10.19308.19308.3 7.39E-05 Oct-72 K.GLEEITVHNKDEVYQILEK.G "sp|P52732|KIF11_HUMAN,tr|A0A7I2YQY4|A0A7I2YQY4_HUMAN,tr|A0A7I2V3A9|A0A7I2V3A9_HUMAN,tr|A0A7I2V3V3|A0A7I2V3V3_HUMAN" 4 2256.1638 999 147405 19308 3 2256.161932 753.0619 Kinesin-like protein KIF11 OS=Homo sapiens OX=9606 GN=KIF11 PE=1 SV=2 4.57 3357.5 - 178950 - - - -0.8182 - 2.363 0.434 - 105.3 1 2 1 -0.0018 19 0 0 0 3.31E+06 0.00E+00 - - - 5.4908 1 221125_WJC_METTL3_EV_vs_WT_F10.19310.19310.3 8.03E-13 19/136 K.VGLPSPSSLVPGSSSQLSGNGNSGTSGPSGSTTSK[136.11].T "sp|Q96CB8|INT12_HUMAN,tr|A0A087WXN4|A0A087WXN4_HUMAN" 2 3182.5419 1.25 147407 19310 3 3182.544825 1061.8546 Integrator complex subunit 12 OS=Homo sapiens OX=9606 GN=INTS12 PE=1 SV=1 8.72 3357.8 - 245234 - - - 0.932 - 3.932 0.683 - 276.3 1 2 0 0.003 35 0 0 0 1.69E+07 1.35E+07 - - - 9.3039 0.9999 221125_WJC_METTL3_EV_vs_WT_F10.19312.19312.3 2.96E-06 Nov-72 K.ER[166.11]VEAVNMAEGIIHDTETK[136.11].M "sp|P38646|GRP75_HUMAN,tr|A0A7I2V2S7|A0A7I2V2S7_HUMAN,tr|A0A7I2V2G2|A0A7I2V2G2_HUMAN,tr|A0A7I2V3F7|A0A7I2V3F7_HUMAN,tr|A0A7I2YQB2|A0A7I2YQB2_HUMAN,tr|D6RCD7|D6RCD7_HUMAN" 6 2159.0648 0.51 147409 19312 3 2159.0651 720.6955 "Stress-70 protein, mitochondrial OS=Homo sapiens OX=9606 GN=HSPA9 PE=1 SV=2" 4.57 3358 - 91942.1 - - - 0.1607 - 2.822 0.593 - 153.5 1 2 1 0.0003 19 0 0 0 8.75E+05 1.70E+06 - - - 7.7001 1 221125_WJC_METTL3_EV_vs_WT_F10.19321.19321.4 2.33E-08 14/198 R.SDSPVPTAPTSGGPK[136.11]PSTASAVPELATDPELEK[136.11]K[136.11].L "sp|Q86U44|MTA70_HUMAN,tr|B4E349|B4E349_HUMAN,tr|F5H6D8|F5H6D8_HUMAN,tr|B4DTN4|B4DTN4_HUMAN" 4 3384.7363 0 147415 19321 4 3384.736013 847.1913 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 4.51 3359.2 - 567109 - - - -0.0733 - 2.734 0.57 - 79.2 1 2 0 -0.0002 34 0 0 0 1.83E+05 5.33E+07 - - - 4.4871 1 221125_WJC_METTL3_EV_vs_WT_F10.19352.19352.4 3.83E-09 14/204 Q.QGSSPAPDSC[160.03]QPGPGPSPGLTSIVSGTSEDLR[166.11]PPR[166.11].R sp|Q96IQ9|ZN414_HUMAN 1 3507.6803 0.85 147432 19352 4 3507.685467 877.9274 Zinc finger protein 414 OS=Homo sapiens OX=9606 GN=ZNF414 PE=1 SV=2 4.56 3363.5 - 129049 - - - 1.4688 - 2.601 0.659 - 58.9 1 1 0 0.0052 35 0 0 0 1.96E+07 2.30E+07 - - - 5.2439 1 221125_WJC_METTL3_EV_vs_WT_F10.19353.19353.3 3.03E-08 13/160 R.TQQTPAAAASGPTPTQPVLPSLALKPTPGGSQPLPTPAQSR.N "sp|Q8IXK0|PHC2_HUMAN,tr|A0A0A0MSI2|A0A0A0MSI2_HUMAN" 2 4016.1331 5.06 147433 19353 3 4016.141458 1339.7183 Polyhomeotic-like protein 2 OS=Homo sapiens OX=9606 GN=PHC2 PE=1 SV=1 11 3363.6 - 117559 - - - 2.0826 - 2.759 0.645 - 49 1 2 0 0.0084 41 0 0 0 4.61E+06 9.11E+05 - - - 8.0636 1 221125_WJC_METTL3_EV_vs_WT_F10.19357.19357.4 0.000187 28/240 R.TQQTPAAAASGPTPTQPVLPSLALK[136.11]PTPGGSQPLPTPAQSR[166.11].N "sp|Q8IXK0|PHC2_HUMAN,tr|A0A0A0MSI2|A0A0A0MSI2_HUMAN" 2 4034.1556 2.06 147435 19357 4 4034.161497 1009.5462 Polyhomeotic-like protein 2 OS=Homo sapiens OX=9606 GN=PHC2 PE=1 SV=1 11 3364.2 - 871759 - - - 1.4707 - 4.037 0.577 - 223.4 1 2 0 0.0059 41 0 0 0 7.47E+07 3.63E+07 - - - 4.6474 1 221125_WJC_METTL3_EV_vs_WT_F10.19371.19371.4 6.07E-11 19/204 Q.QGSSPAPDSC[160.03]QPGPGPSPGLTSIVSGTSEDLRPPR.R sp|Q96IQ9|ZN414_HUMAN 1 3487.6638 0.85 147444 19371 4 3487.668223 872.9232 Zinc finger protein 414 OS=Homo sapiens OX=9606 GN=ZNF414 PE=1 SV=2 4.56 3366.2 - 136829 - - - 1.2754 - 3.193 0.653 - 143.5 1 1 0 0.0044 35 0 0 0 1.96E+07 2.30E+07 - - - 5.2527 0.9882 221125_WJC_METTL3_EV_vs_WT_F10.19377.19377.3 8.10E-05 6/136 Q.QGSSPAPDSC[160.03]QPGPGPSPGLTSIVSGTSEDLR[166.11]PPR[166.11].R sp|Q96IQ9|ZN414_HUMAN 1 3507.6803 1.12 147446 19377 3 3507.683878 1170.234 Zinc finger protein 414 OS=Homo sapiens OX=9606 GN=ZNF414 PE=1 SV=2 4.56 3367.1 - 50972.4 - - - 1.0158 - 1.503 0.511 - 15.5 1 1 0 0.0036 35 0 0 0 5.96E+06 5.31E+06 - - - 5.1736 1 221125_WJC_METTL3_EV_vs_WT_F10.19379.19379.3 6.81E-09 12/136 K.VGLPSPSSLVPGSSSQLSGNGNSGTSGPSGSTTSK.T "sp|Q96CB8|INT12_HUMAN,tr|A0A087WXN4|A0A087WXN4_HUMAN" 2 3174.5277 1.24 147447 19379 3 3174.527498 1059.1832 Integrator complex subunit 12 OS=Homo sapiens OX=9606 GN=INTS12 PE=1 SV=1 8.72 3367.3 - 53948.3 - - - -0.0507 - 2.689 0.642 - 97.7 1 2 0 -0.0002 35 0 0 0 1.81E+07 1.47E+07 - - - 7.9733 0.9892 221125_WJC_METTL3_EV_vs_WT_F10.19414.19414.3 7.53E-10 10/136 Q.QGSSPAPDSC[160.03]QPGPGPSPGLTSIVSGTSEDLRPPR.R sp|Q96IQ9|ZN414_HUMAN 1 3487.6638 1.13 147462 19414 3 3487.678778 1163.5619 Zinc finger protein 414 OS=Homo sapiens OX=9606 GN=ZNF414 PE=1 SV=2 4.56 3372.4 - 72534.5 - - - 4.3017 - 2.43 0.685 - 36.3 1 1 0 0.015 35 0 0 0 6.05E+06 5.34E+06 - - - 8.2156 0.927 221125_WJC_METTL3_EV_vs_WT_F10.19430.19430.4 0.000619 7/204 R.SNGTNTSAPQDIYAVNGIAFHPVHGTLATVGSDGR[166.11].F "sp|P78406|RAE1L_HUMAN,tr|E9PQ57|E9PQ57_HUMAN" 2 3533.7163 3.02 147468 19430 4 3534.702107 884.4363 mRNA export factor OS=Homo sapiens OX=9606 GN=RAE1 PE=1 SV=1 5.93 3374.7 - 102630 - - - 278.9737 - 1.867 0.424 - 15.5 1 2 0 0.9858 35 0 0 0 6.18E+06 2.05E+06 - - - 2.8285 0.9997 221125_WJC_METTL3_EV_vs_WT_F10.19451.19451.3 6.55E-05 Aug-64 R.DLIGHIVEFSQDQHGSR.F "sp|Q8TB72|PUM2_HUMAN,tr|A0A0C4DG68|A0A0C4DG68_HUMAN" 2 1936.9391 1.33 147476 19451 3 1936.933779 646.6537 Pumilio homolog 2 OS=Homo sapiens OX=9606 GN=PUM2 PE=1 SV=2 5.21 3378.2 - 49455.2 - - - -2.7667 - 1.646 0.496 - 59.5 1 2 0 -0.0054 17 0 0 0 3.94E+06 2.96E+06 - - - 5.3274 0.9501 221125_WJC_METTL3_EV_vs_WT_F10.19499.19499.3 0.038 May-64 R.HGVQELEIELQSQLSKK.A "sp|P35527|K1C9_HUMAN,tr|K7EQQ3|K7EQQ3_HUMAN" 2 1965.0531 999 147502 19499 3 1965.059976 656.025 "Keratin, type I cytoskeletal 9 OS=Homo sapiens OX=9606 GN=KRT9 PE=1 SV=3" 5.5 3384.7 - 57900.2 - - - 3.4966 - 1.094 0.276 - 25.9 1 2 0 0.0069 17 0 0 0 3.55E+06 0.00E+00 - - - 1.8422 0.9814 221125_WJC_METTL3_EV_vs_WT_F10.19502.19502.3 0.0539 May-68 R.DVQIGDIVTVGEC[160.03]RPLSK.T "sp|P62280|RS11_HUMAN,tr|M0R1H5|M0R1H5_HUMAN" 2 1985.0252 1.11 147503 19502 3 1985.029071 662.6823 40S ribosomal protein S11 OS=Homo sapiens OX=9606 GN=RPS11 PE=1 SV=3 4.56 3385.2 - 57899.9 - - - 1.9622 - 1.335 0.229 - 22.5 1 2 0 0.0039 18 0 0 0 9.84E+05 8.84E+05 - - - 1.8115 0.9977 221125_WJC_METTL3_EV_vs_WT_F10.19524.19524.4 0.00303 8/192 R.SALPVSPSISSAPVPVEIENLPQSPGTDQHDRK.C sp|Q9HCM4|E41L5_HUMAN 1 3451.7583 0.92 147514 19524 4 3451.773351 863.9469 Band 4.1-like protein 5 OS=Homo sapiens OX=9606 GN=EPB41L5 PE=1 SV=3 4.75 3388.4 - 87862.3 - - - 4.3526 - 1.933 0.372 - 21 1 2 0 0.015 33 0 0 0 1.95E+06 2.11E+06 - - - 2.6575 1 221125_WJC_METTL3_EV_vs_WT_F10.19525.19525.4 1.01E-07 8/144 R.TNHEDSDKDHSFLTNDELAVLPVVK.V sp|Q12923|PTN13_HUMAN 1 2822.3723 0.76 147515 19525 4 2822.382787 706.6003 Tyrosine-protein phosphatase non-receptor type 13 OS=Homo sapiens OX=9606 GN=PTPN13 PE=1 SV=2 4.51 3388.6 - 88183.9 - - - 3.7274 - 1.965 0.645 - 44.7 1 2 1 0.0105 25 0 0 0 9.04E+05 1.19E+06 - - - 5.0521 0.9999 221125_WJC_METTL3_EV_vs_WT_F10.19543.19543.3 1.72E-09 Dec-72 R.MDSFDEDLARPSGLLAQER.K "sp|Q9Y2W1|TR150_HUMAN,tr|A0A3B3ITZ9|A0A3B3ITZ9_HUMAN" 2 2149.011 5.3 147524 19543 3 2149.019399 717.3443 Thyroid hormone receptor-associated protein 3 OS=Homo sapiens OX=9606 GN=THRAP3 PE=1 SV=2 4.1 3391.1 - 139629 - - - 3.9162 - 2.508 0.606 - 214.2 1 2 0 0.0084 19 0 0 0 9.27E+06 1.75E+06 - - - 7.553 0.9999 221125_WJC_METTL3_EV_vs_WT_F10.19556.19556.3 4.23E-06 Oct-72 R.MDSFDEDLAR[166.11]PSGLLAQER[166.11].K "sp|Q9Y2W1|TR150_HUMAN,tr|A0A3B3ITZ9|A0A3B3ITZ9_HUMAN" 2 2169.0275 5.35 147531 19556 3 2169.031348 724.0165 Thyroid hormone receptor-associated protein 3 OS=Homo sapiens OX=9606 GN=THRAP3 PE=1 SV=2 4.1 3393 - 93734.4 - - - 1.7635 - 2.327 0.482 - 125.4 1 2 0 0.0038 19 0 0 0 9.13E+06 1.71E+06 - - - 5.9877 0.9999 221125_WJC_METTL3_EV_vs_WT_F10.19564.19564.3 4.84E-07 Nov-68 K.TVTNAVVTVPAYFNDSQR[166.11].Q "sp|P11142|HSP7C_HUMAN,tr|E9PQQ4|E9PQQ4_HUMAN,tr|E9PN89|E9PN89_HUMAN,tr|E9PLF4|E9PLF4_HUMAN,tr|E9PI65|E9PI65_HUMAN,tr|E9PK54|E9PK54_HUMAN,tr|E9PQK7|E9PQK7_HUMAN" 7 1990.9988 0.14 147537 19564 3 1991.005365 664.6735 Heat shock cognate 71 kDa protein OS=Homo sapiens OX=9606 GN=HSPA8 PE=1 SV=1 5.5 3394.1 - 83999.3 - - - 3.3099 - 2.288 0.588 - 155.3 1 2 0 0.0066 18 0 0 0 1.69E+06 1.22E+07 - - - 7.1548 0.9998 221125_WJC_METTL3_EV_vs_WT_F10.19571.19571.2 0.00117 Jul-34 K.TVTNAVVTVPAYFNDSQR[166.11].Q "sp|P11142|HSP7C_HUMAN,tr|E9PQQ4|E9PQQ4_HUMAN,tr|E9PN89|E9PN89_HUMAN,tr|E9PLF4|E9PLF4_HUMAN,tr|E9PI65|E9PI65_HUMAN,tr|E9PK54|E9PK54_HUMAN,tr|E9PQK7|E9PQK7_HUMAN" 7 1990.9988 0.001 147540 19571 2 1990.998801 996.5067 Heat shock cognate 71 kDa protein OS=Homo sapiens OX=9606 GN=HSPA8 PE=1 SV=1 5.5 3395.1 - 36418.6 - - - 0.0131 - 1.564 0.524 - 101.4 1 2 0 0 18 0 0 0 0.00E+00 1.96E+06 - - - 4.0108 0.9795 221125_WJC_METTL3_EV_vs_WT_F10.19575.19575.2 0.369 16-Jun R.YLDVSILGK[136.11].F sp|Q86U44|MTA70_HUMAN 1 1014.5841 0.01 147542 19575 2 1014.586838 508.2993 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 5.83 3395.7 - 51843.7 - - - 2.7006 - 1.128 0.221 - 80.1 1 2 0 0.0027 9 0 0 0 1.36E+06 1.09E+08 - - - 1.0209 0.9992 221125_WJC_METTL3_EV_vs_WT_F10.19584.19584.3 0.000407 Aug-68 K.QQLSAEELDAQLDAYNAR[166.11].M "sp|Q86V81|THOC4_HUMAN,tr|E9PB61|E9PB61_HUMAN" 2 2043.9737 0.62 147547 19584 3 2043.9814 682.3318 THO complex subunit 4 OS=Homo sapiens OX=9606 GN=ALYREF PE=1 SV=3 3.92 3397 - 63034.2 - - - 3.7755 - 1.607 0.473 - 86.7 1 2 0 0.0077 18 0 0 0 1.36E+06 2.17E+06 - - - 4.9926 1 221125_WJC_METTL3_EV_vs_WT_F10.19588.19588.4 1.05E-14 18/138 K.KGADSLEDFLYHEGYAC[160.03]TSIHGDR.S "sp|O00571|DDX3X_HUMAN,sp|O15523|DDX3Y_HUMAN,tr|A0A2R8YFR4|A0A2R8YFR4_HUMAN,tr|A0A2R8YCW1|A0A2R8YCW1_HUMAN,tr|A0A2R8YDH3|A0A2R8YDH3_HUMAN,tr|A0A2R8YDT5|A0A2R8YDT5_HUMAN,tr|A0A2R8Y645|A0A2R8Y645_HUMAN,tr|A0A2R8YF78|A0A2R8YF78_HUMAN,tr|A0A0D9SFB3|A0A0D9SFB3_HUMAN,tr|A0A2R8YFS5|A0A2R8YFS5_HUMAN,tr|A0A0D9SF53|A0A0D9SF53_HUMAN,tr|A0A0J9YVQ7|A0A0J9YVQ7_HUMAN,tr|A0A2R8Y5G6|A0A2R8Y5G6_HUMAN,tr|A0A2R8Y7T2|A0A2R8Y7T2_HUMAN,tr|A0A0D9SG12|A0A0D9SG12_HUMAN,tr|F6S8Q4|F6S8Q4_HUMAN,tr|A0A2U3TZJ9|A0A2U3TZJ9_HUMAN,tr|A0A2R8Y4A4|A0A2R8Y4A4_HUMAN" 18 2740.2187 1.04 147549 19588 4 2740.224231 686.062 ATP-dependent RNA helicase DDX3X OS=Homo sapiens OX=9606 GN=DDX3X PE=1 SV=3 4.8 3397.6 - 142683 - - - 2.0024 - 4.306 0.755 - 208.6 1 2 0 0.0055 24 0 0 0 1.14E+07 1.09E+07 - - - 6.2646 0.9986 221125_WJC_METTL3_EV_vs_WT_F10.19603.19603.3 0.000627 Aug-68 K.QQLSAEELDAQLDAYNAR.M "sp|Q86V81|THOC4_HUMAN,tr|E9PB61|E9PB61_HUMAN" 2 2033.9654 0.65 147556 19603 3 2033.971148 678.9957 THO complex subunit 4 OS=Homo sapiens OX=9606 GN=ALYREF PE=1 SV=3 3.92 3399.7 - 78269 - - - 2.8196 - 1.596 0.382 - 78.3 1 2 0 0.0057 18 0 0 0 1.43E+06 2.21E+06 - - - 3.9615 1 221125_WJC_METTL3_EV_vs_WT_F10.19612.19612.4 4.99E-09 24/138 K.K[136.11]GADSLEDFLYHEGYAC[160.03]TSIHGDR[166.11].S "sp|O00571|DDX3X_HUMAN,sp|O15523|DDX3Y_HUMAN,tr|A0A2R8YFR4|A0A2R8YFR4_HUMAN,tr|A0A2R8YCW1|A0A2R8YCW1_HUMAN,tr|A0A2R8YDH3|A0A2R8YDH3_HUMAN,tr|A0A2R8YDT5|A0A2R8YDT5_HUMAN,tr|A0A2R8Y645|A0A2R8Y645_HUMAN,tr|A0A2R8YF78|A0A2R8YF78_HUMAN,tr|A0A0D9SFB3|A0A0D9SFB3_HUMAN,tr|A0A2R8YFS5|A0A2R8YFS5_HUMAN,tr|A0A0D9SF53|A0A0D9SF53_HUMAN,tr|A0A0J9YVQ7|A0A0J9YVQ7_HUMAN,tr|A0A2R8Y5G6|A0A2R8Y5G6_HUMAN,tr|A0A2R8Y7T2|A0A2R8Y7T2_HUMAN,tr|A0A0D9SG12|A0A0D9SG12_HUMAN,tr|F6S8Q4|F6S8Q4_HUMAN,tr|A0A2U3TZJ9|A0A2U3TZJ9_HUMAN,tr|A0A2R8Y4A4|A0A2R8Y4A4_HUMAN" 18 2758.2412 1.04 147559 19612 4 2758.237175 690.5676 ATP-dependent RNA helicase DDX3X OS=Homo sapiens OX=9606 GN=DDX3X PE=1 SV=3 4.8 3401 - 420065 - - - -1.4643 - 4.573 0.679 - 329.6 1 2 0 -0.004 24 0 0 0 1.14E+07 1.09E+07 - - - 5.6228 0.9993 221125_WJC_METTL3_EV_vs_WT_F10.19619.19619.3 0.0015 Jun-68 R.SPSELFAQHIVTIVHHVK.E "sp|Q9Y2W1|TR150_HUMAN,tr|A0A3B3ITZ9|A0A3B3ITZ9_HUMAN" 2 2041.1109 2.5 147562 19619 3 2041.111796 681.3776 Thyroid hormone receptor-associated protein 3 OS=Homo sapiens OX=9606 GN=THRAP3 PE=1 SV=2 6.78 3401.9 - 143720 - - - 0.4414 - 1.331 0.384 - 29.1 1 2 0 0.0009 18 0 0 0 6.35E+07 2.54E+07 - - - 3.533 1 221125_WJC_METTL3_EV_vs_WT_F10.19631.19631.4 5.55E-07 16/198 R.SDSPVPTAPTSGGPK[136.11]PSTASAVPELATDPELEK[136.11]K[136.11].L "sp|Q86U44|MTA70_HUMAN,tr|B4E349|B4E349_HUMAN,tr|F5H6D8|F5H6D8_HUMAN,tr|B4DTN4|B4DTN4_HUMAN" 4 3384.7363 0.05 147566 19631 4 3384.730496 847.1913 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 4.51 3403.7 - 567218 - - - -1.7032 - 2.317 0.528 - 60.6 1 2 0 -0.0058 34 0 0 0 3.09E+06 6.41E+07 - - - 4.0707 0.9997 221125_WJC_METTL3_EV_vs_WT_F10.19638.19638.3 1.89E-05 Sep-44 R.AR[166.11]FEELC[160.03]SDLFR[166.11].S "sp|P48741|HSP77_HUMAN,sp|P0DMV8|HS71A_HUMAN,sp|P0DMV9|HS71B_HUMAN,sp|P17066|HSP76_HUMAN,tr|V9GZ37|V9GZ37_HUMAN,tr|A0A0G2JIW1|A0A0G2JIW1_HUMAN" 6 1561.7462 0.02 147570 19638 3 1561.742779 521.5893 Putative heat shock 70 kDa protein 7 OS=Homo sapiens OX=9606 GN=HSPA7 PE=5 SV=2 4.68 3404.6 - 172788 - - - -2.1924 - 1.825 0.567 - 176.8 1 2 1 -0.0034 12 0 0 0 9.76E+04 5.55E+06 - - - 6.528 1 221125_WJC_METTL3_EV_vs_WT_F10.19646.19646.4 1.57E-05 10/162 K.NDQNNC[160.03]PVKPC[160.03]YLNILEDEQPLNSAAHK.E "sp|Q15154|PCM1_HUMAN,tr|H0YBA1|H0YBA1_HUMAN,tr|A0A5H1ZRS1|A0A5H1ZRS1_HUMAN" 3 3280.5241 3.61 147572 19646 4 3280.527934 821.1383 Pericentriolar material 1 protein OS=Homo sapiens OX=9606 GN=PCM1 PE=1 SV=5 4.75 3405.8 - 234310 - - - 1.1654 - 2.026 0.584 - 31.3 1 2 0 0.0038 28 0 0 0 3.50E+06 9.70E+05 - - - 4.5273 1 221125_WJC_METTL3_EV_vs_WT_F10.19653.19653.2 4.32E-08 26-Dec R.GVVDSEDIPLNLSR.E "sp|Q12931|TRAP1_HUMAN,sp|P08238|HS90B_HUMAN,sp|Q58FF7|H90B3_HUMAN,sp|P07900|HS90A_HUMAN,tr|I3L0K7|I3L0K7_HUMAN,tr|I3L239|I3L239_HUMAN" 6 1512.7784 0.63 147575 19653 2 1512.776708 757.3965 "Heat shock protein 75 kDa, mitochondrial OS=Homo sapiens OX=9606 GN=TRAP1 PE=1 SV=3" 4.03 3406.6 - 358189 - - - -1.1099 - 2.486 0.644 - 391.2 1 2 0 -0.0017 14 0 0 0 1.64E+07 2.62E+07 - - - 6.0823 1 221125_WJC_METTL3_EV_vs_WT_F10.19661.19661.3 3.05E-09 13/68 R.SPSELFAQHIVTIVHHVK[136.11].E "sp|Q9Y2W1|TR150_HUMAN,tr|A0A3B3ITZ9|A0A3B3ITZ9_HUMAN" 2 2049.1251 2.5 147578 19661 3 2049.121333 684.049 Thyroid hormone receptor-associated protein 3 OS=Homo sapiens OX=9606 GN=THRAP3 PE=1 SV=2 6.78 3407.7 - 137854 - - - -1.8359 - 2.512 0.598 - 171.7 1 2 0 -0.0038 18 0 0 0 6.35E+07 2.54E+07 - - - 7.4996 0.9017 221125_WJC_METTL3_EV_vs_WT_F10.19667.19667.2 0.00958 26-May R.GLLQDDAHPTLVTY.A "sp|Q86U44|MTA70_HUMAN,tr|F5H6D8|F5H6D8_HUMAN,tr|H0YFV6|H0YFV6_HUMAN,tr|B4DTN4|B4DTN4_HUMAN" 4 1541.7726 - 147579 19667 2 1541.774476 771.8936 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 4.2 3408.6 - 135014 - - - 1.2343 - 1.271 0.346 - 61.9 1 1 0 0.0019 14 0 0 0 - - - - - 2.1977 0.9933 221125_WJC_METTL3_EV_vs_WT_F10.19679.19679.3 7.02E-09 11/136 K.VGLPSPSSLVPGSSSQLSGNGNSGTSGPSGSTTSK[136.11].T "sp|Q96CB8|INT12_HUMAN,tr|A0A087WXN4|A0A087WXN4_HUMAN" 2 3182.5419 -1 147583 19679 3 3183.532102 1061.8546 Integrator complex subunit 12 OS=Homo sapiens OX=9606 GN=INTS12 PE=1 SV=1 8.72 3410.3 - 102148 - - - 311.1485 - 2.609 0.551 - 76.7 1 2 0 0.9902 35 0 0 0 0.00E+00 0.00E+00 - - - 6.615 0.9924 221125_WJC_METTL3_EV_vs_WT_F10.19683.19683.3 0.157 May-56 R.GFAFVTFDDHDSVDK[136.11].L "sp|Q32P51|RA1L2_HUMAN,sp|P09651|ROA1_HUMAN,tr|A0A7I2YQX9|A0A7I2YQX9_HUMAN,tr|F8VZ49|F8VZ49_HUMAN,tr|A0A7I2V3R8|A0A7I2V3R8_HUMAN,tr|F8VTQ5|F8VTQ5_HUMAN,tr|F8W6I7|F8W6I7_HUMAN,tr|H0YH80|H0YH80_HUMAN,tr|A0A7I2V2L6|A0A7I2V2L6_HUMAN,tr|A0A7I2V3W0|A0A7I2V3W0_HUMAN,tr|A0A7I2V5U9|A0A7I2V5U9_HUMAN,tr|A0A2R8Y4L2|A0A2R8Y4L2_HUMAN" 12 1706.7668 1.15 147585 19683 3 1706.767188 569.9295 Heterogeneous nuclear ribonucleoprotein A1-like 2 OS=Homo sapiens OX=9606 GN=HNRNPA1L2 PE=2 SV=2 4.13 3410.8 - 41082 - - - 0.2473 - 0.899 0.333 - 18.5 1 2 0 0.0004 15 0 0 0 3.84E+06 3.33E+06 - - - 1.9747 0.9991 221125_WJC_METTL3_EV_vs_WT_F10.19688.19688.3 1.81E-07 12/136 K.VGLPSPSSLVPGSSSQLSGNGNSGTSGPSGSTTSK.T "sp|Q96CB8|INT12_HUMAN,tr|A0A087WXN4|A0A087WXN4_HUMAN" 2 3174.5277 4 147587 19688 3 3175.524714 1059.1832 Integrator complex subunit 12 OS=Homo sapiens OX=9606 GN=INTS12 PE=1 SV=1 8.72 3411.6 - 137830 - - - 314.0798 - 2.332 0.633 - 92.4 1 2 0 0.9971 35 0 0 0 1.46E+06 3.65E+05 - - - 7.2691 0.9994 221125_WJC_METTL3_EV_vs_WT_F10.19696.19696.3 0.0235 Sep-56 R.GFAFVTFDDHDSVDK.L "sp|Q32P51|RA1L2_HUMAN,sp|P09651|ROA1_HUMAN,tr|A0A7I2YQX9|A0A7I2YQX9_HUMAN,tr|F8VZ49|F8VZ49_HUMAN,tr|A0A7I2V3R8|A0A7I2V3R8_HUMAN,tr|F8VTQ5|F8VTQ5_HUMAN,tr|F8W6I7|F8W6I7_HUMAN,tr|H0YH80|H0YH80_HUMAN,tr|A0A7I2V2L6|A0A7I2V2L6_HUMAN,tr|A0A7I2V3W0|A0A7I2V3W0_HUMAN,tr|A0A7I2V5U9|A0A7I2V5U9_HUMAN,tr|A0A2R8Y4L2|A0A2R8Y4L2_HUMAN" 12 1698.7526 1.15 147590 19696 3 1698.756806 567.2581 Heterogeneous nuclear ribonucleoprotein A1-like 2 OS=Homo sapiens OX=9606 GN=HNRNPA1L2 PE=2 SV=2 4.13 3412.8 - 96901.2 - - - 2.4959 - 1.809 0.4 - 64.8 1 2 0 0.0042 15 0 0 0 3.84E+06 3.33E+06 - - - 4.5452 0.9993 221125_WJC_METTL3_EV_vs_WT_F10.19719.19719.4 1.49E-05 11/150 K.QLPDKWQHDLFDSGFGGGAGVETGGK.L "sp|Q86V81|THOC4_HUMAN,tr|E9PB61|E9PB61_HUMAN" 2 2702.2725 0.72 147600 19719 4 2702.281618 676.5754 THO complex subunit 4 OS=Homo sapiens OX=9606 GN=ALYREF PE=1 SV=3 4.66 3416.3 - 116351 - - - 3.3764 - 1.903 0.498 - 70.4 1 2 1 0.0091 26 0 0 0 5.07E+06 7.00E+06 - - - 3.761 0.9973 221125_WJC_METTL3_EV_vs_WT_F10.19742.19742.3 0.00621 Jun-92 K.YEHDDIVSTVSVLSSGTQAVSGSK.D "sp|Q9BQA1|MEP50_HUMAN,tr|H0Y711|H0Y711_HUMAN" 2 2465.1922 2.33 147607 19742 3 2465.182881 822.738 Methylosome protein 50 OS=Homo sapiens OX=9606 GN=WDR77 PE=1 SV=1 4.54 3419.7 - 60061 - - - -3.7713 - 1.346 0.426 - 25.1 1 2 0 -0.0093 24 0 0 0 3.83E+06 1.64E+06 - - - 3.977 1 221125_WJC_METTL3_EV_vs_WT_F10.19798.19798.4 2.89E-10 22/102 R.SPSELFAQHIVTIVHHVK.E "sp|Q9Y2W1|TR150_HUMAN,tr|A0A3B3ITZ9|A0A3B3ITZ9_HUMAN" 2 2041.1109 2.72 147635 19798 4 2041.113647 511.285 Thyroid hormone receptor-associated protein 3 OS=Homo sapiens OX=9606 GN=THRAP3 PE=1 SV=2 6.78 3427.4 - 3.04E+06 - - - 1.3483 - 3.662 0.594 - 356 1 2 0 0.0028 18 0 0 0 2.67E+08 9.83E+07 - - - 4.8401 1 221125_WJC_METTL3_EV_vs_WT_F10.19812.19812.4 5.59E-12 22/192 K.R[166.11]K[136.11]ELEQVC[160.03]NPIISGLYQGAGGPGPGGFGAQGPK[136.11].G "sp|P0DMV8|HS71A_HUMAN,sp|P0DMV9|HS71B_HUMAN,tr|V9GZ37|V9GZ37_HUMAN,tr|A0A0G2JIW1|A0A0G2JIW1_HUMAN" 4 3364.7197 0.97 147641 19812 4 3364.724725 842.1872 Heat shock 70 kDa protein 1A OS=Homo sapiens OX=9606 GN=HSPA1A PE=1 SV=1 8.18 3429.6 - 227388 - - - 1.5041 - 4.539 0.679 - 228 1 2 1 0.0051 33 0 0 0 1.83E+07 1.88E+07 - - - 5.5885 1 221125_WJC_METTL3_EV_vs_WT_F10.19829.19829.4 1.32E-09 24/102 R.SPSELFAQHIVTIVHHVK[136.11].E "sp|Q9Y2W1|TR150_HUMAN,tr|A0A3B3ITZ9|A0A3B3ITZ9_HUMAN" 2 2049.1251 2.71 147651 19829 4 2049.128811 513.2886 Thyroid hormone receptor-associated protein 3 OS=Homo sapiens OX=9606 GN=THRAP3 PE=1 SV=2 6.78 3432 - 739774 - - - 1.8135 - 3.997 0.633 - 513.7 1 2 0 0.0037 18 0 0 0 2.67E+08 9.83E+07 - - - 5.2092 1 221125_WJC_METTL3_EV_vs_WT_F10.19831.19831.3 2.98E-10 13/68 R.SPSELFAQHIVTIVHHVK.E "sp|Q9Y2W1|TR150_HUMAN,tr|A0A3B3ITZ9|A0A3B3ITZ9_HUMAN" 2 2041.1109 2.5 147652 19831 3 2041.115321 681.3776 Thyroid hormone receptor-associated protein 3 OS=Homo sapiens OX=9606 GN=THRAP3 PE=1 SV=2 6.78 3432.2 - 306767 - - - 2.1684 - 3.127 0.609 - 187.7 1 2 0 0.0044 18 0 0 0 6.35E+07 2.54E+07 - - - 8.1674 0.995 221125_WJC_METTL3_EV_vs_WT_F10.19832.19832.2 0.00413 Jun-32 R.AETEC[160.03]QNTEYQQLLDIK.L "sp|P13645|K1C10_HUMAN,tr|A0A1B0GVI3|A0A1B0GVI3_HUMAN" 2 2081.9576 999 147653 19832 2 2081.958111 1041.9861 "Keratin, type I cytoskeletal 10 OS=Homo sapiens OX=9606 GN=KRT10 PE=1 SV=6" 4 3432.3 - 30115.3 - - - 0.2695 - 1.327 0.188 - 79 1 2 0 0.0006 17 0 0 0 1.82E+06 0.00E+00 - - - 1.125 0.9981 221125_WJC_METTL3_EV_vs_WT_F10.19835.19835.4 0.0107 7/156 K.TKEQASHLGGAVFSGAGNIAAATGLVK.R "sp|Q16143|SYUB_HUMAN,tr|G4Y816|G4Y816_HUMAN" 2 2554.3504 1.45 147654 19835 4 2554.357106 639.5949 Beta-synuclein OS=Homo sapiens OX=9606 GN=SNCB PE=1 SV=1 8.29 3432.8 - 97458.7 - - - 2.6449 - 1.41 0.4 - 25.4 1 2 1 0.0068 27 0 0 0 4.13E+06 2.85E+06 - - - 2.8132 1 221125_WJC_METTL3_EV_vs_WT_F10.19837.19837.3 0.000203 Oct-64 R.AETEC[160.03]QNTEYQQLLDIK.L "sp|P13645|K1C10_HUMAN,tr|A0A1B0GVI3|A0A1B0GVI3_HUMAN" 2 2081.9576 999 147655 19837 3 2081.959118 694.9931 "Keratin, type I cytoskeletal 10 OS=Homo sapiens OX=9606 GN=KRT10 PE=1 SV=6" 4 3433 - 126355 - - - 0.7531 - 2.253 0.49 - 170.9 1 2 0 0.0016 17 0 0 0 7.11E+06 0.00E+00 - - - 6.0546 0.9991 221125_WJC_METTL3_EV_vs_WT_F10.19838.19838.4 0.0002 9/156 K.TK[136.11]EQASHLGGAVFSGAGNIAAATGLVK[136.11].R "sp|Q16143|SYUB_HUMAN,tr|G4Y816|G4Y816_HUMAN" 2 2570.3787 1.45 147656 19838 4 2570.381088 643.602 Beta-synuclein OS=Homo sapiens OX=9606 GN=SNCB PE=1 SV=1 8.29 3433.1 - 58427.9 - - - 0.9096 - 1.631 0.385 - 37.3 1 2 1 0.0023 27 0 0 0 4.13E+06 2.85E+06 - - - 2.7295 1 221125_WJC_METTL3_EV_vs_WT_F10.19847.19847.4 1.85E-09 14/198 R.SDSPVPTAPTSGGPK[136.11]PSTASAVPELATDPELEK[136.11]K[136.11].L "sp|Q86U44|MTA70_HUMAN,tr|B4E349|B4E349_HUMAN,tr|F5H6D8|F5H6D8_HUMAN,tr|B4DTN4|B4DTN4_HUMAN" 4 3384.7363 0.3 147658 19847 4 3384.740995 847.1913 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 4.51 3434.7 - 382904 - - - 1.3986 - 2.958 0.57 - 70.5 1 2 0 0.0047 34 0 0 0 6.45E+06 2.14E+07 - - - 4.5094 0.9997 221125_WJC_METTL3_EV_vs_WT_F10.19849.19849.4 0.000137 12/138 K.QHNSGPNSKPVVSFIAGLTAPPGR.R sp|P53597|SUCA_HUMAN 1 2430.2768 1.71 147659 19849 4 2430.283514 608.5765 "Succinate--CoA ligase [ADP\GDP-forming] subunit alpha, mitochondrial OS=Homo sapiens OX=9606 GN=SUCLG1 PE=1 SV=4" 11 3434.9 - 233311 - - - 2.7664 - 2.632 0.422 - 78.8 1 2 0 0.0067 24 0 0 0 1.38E+07 8.09E+06 - - - 3.2078 0.9999 221125_WJC_METTL3_EV_vs_WT_F10.19851.19851.4 6.32E-06 8/156 R.HAEQQASRPPPPNSVIHLPFIIVNTSK.K sp|Q14186|TFDP1_HUMAN 1 2976.5934 2.85 147661 19851 4 2976.602582 745.1556 Transcription factor Dp-1 OS=Homo sapiens OX=9606 GN=TFDP1 PE=1 SV=1 8.76 3435.2 - 73489.7 - - - 3.0935 - 1.984 0.562 - 31.5 1 2 0 0.0092 27 0 0 0 5.84E+06 2.05E+06 - - - 4.3295 1 221125_WJC_METTL3_EV_vs_WT_F10.19857.19857.4 6.34E-11 16/246 K.LDRPAGGPSAESPRPSSAYNGDLNGLLVPDPLC[160.03]SGDSTSANK.T sp|Q6P2E9|EDC4_HUMAN 1 4239.0138 1.05 147663 19857 4 4239.019063 1060.7607 Enhancer of mRNA-decapping protein 4 OS=Homo sapiens OX=9606 GN=EDC4 PE=1 SV=1 4.36 3436.1 - 158074 - - - 1.2314 - 2.817 0.569 - 72.7 1 2 0 0.0052 42 0 0 0 7.98E+06 7.61E+06 - - - 4.4732 1 221125_WJC_METTL3_EV_vs_WT_F10.19858.19858.4 8.92E-06 12/186 K.SIDDTSNFDEFPESDILKPTVATSNHPETDYK.N sp|Q15208|STK38_HUMAN 1 3611.6427 4.34 147664 19858 4 3611.647428 903.918 Serine\threonine-protein kinase 38 OS=Homo sapiens OX=9606 GN=STK38 PE=1 SV=1 4.02 3436.2 - 126958 - - - 1.2958 - 2.062 0.583 - 49.2 1 2 0 0.0047 32 0 0 0 4.02E+07 9.27E+06 - - - 4.5176 1 221125_WJC_METTL3_EV_vs_WT_F10.19868.19868.4 5.62E-09 22/246 K.LDR[166.11]PAGGPSAESPR[166.11]PSSAYNGDLNGLLVPDPLC[160.03]SGDSTSANK[136.11].T sp|Q6P2E9|EDC4_HUMAN 1 4267.0446 1.05 147670 19868 4 4267.047139 1067.7684 Enhancer of mRNA-decapping protein 4 OS=Homo sapiens OX=9606 GN=EDC4 PE=1 SV=1 4.36 3437.5 - 246073 - - - 0.599 - 2.69 0.65 - 147.1 1 2 0 0.0026 42 0 0 0 7.98E+06 7.61E+06 - - - 5.1658 0.9967 221125_WJC_METTL3_EV_vs_WT_F10.19884.19884.4 0.158 7/156 R.HAEQQASR[166.11]PPPPNSVIHLPFIIVNTSK[136.11].K sp|Q14186|TFDP1_HUMAN 1 2994.6158 3.01 147678 19884 4 2994.618591 749.6612 Transcription factor Dp-1 OS=Homo sapiens OX=9606 GN=TFDP1 PE=1 SV=1 8.76 3439.8 - 110670 - - - 0.9173 - 1.746 0.25 - 18.1 1 2 0 0.0027 27 0 0 0 5.83E+06 1.94E+06 - - - 1.5756 0.9997 221125_WJC_METTL3_EV_vs_WT_F10.19899.19899.4 0.000189 6/108 K.KISSIQSIVPALEIANAHR.K "sp|P10809|CH60_HUMAN,tr|A0A7I2V2X6|A0A7I2V2X6_HUMAN,tr|A0A7I2YQK6|A0A7I2YQK6_HUMAN,tr|A0A7I2V599|A0A7I2V599_HUMAN,tr|A0A7I2YQ71|A0A7I2YQ71_HUMAN,tr|A0A7I2V5M1|A0A7I2V5M1_HUMAN,tr|A0A7I2V5K3|A0A7I2V5K3_HUMAN,tr|A0A7I2V369|A0A7I2V369_HUMAN" 8 2046.1586 1.36 147686 19899 4 2046.163118 512.5469 "60 kDa heat shock protein, mitochondrial OS=Homo sapiens OX=9606 GN=HSPD1 PE=1 SV=2" 8.75 3441.8 - 118213 - - - 2.2212 - 1.762 0.399 - 26.8 1 2 0 0.0045 19 0 0 0 1.34E+07 9.87E+06 - - - 2.8893 0.9997 221125_WJC_METTL3_EV_vs_WT_F10.19906.19906.3 0.000325 6/124 K.SIDDTSNFDEFPESDILKPTVATSNHPETDYK.N sp|Q15208|STK38_HUMAN 1 3611.6427 26.16 147691 19906 3 3611.644948 1204.8882 Serine\threonine-protein kinase 38 OS=Homo sapiens OX=9606 GN=STK38 PE=1 SV=1 4.02 3442.7 - 69747.5 - - - 0.6091 - 1.363 0.444 - 18.3 1 2 0 0.0022 32 0 0 0 1.23E+06 4.69E+04 - - - 4.202 0.9871 221125_WJC_METTL3_EV_vs_WT_F10.19909.19909.3 0.058 Aug-56 R.GFGFVTFDDHDPVDK[136.11].L "sp|P22626|ROA2_HUMAN,tr|A0A7I2V4N0|A0A7I2V4N0_HUMAN,tr|A0A024RA28|A0A024RA28_HUMAN,tr|A0A7I2V4N1|A0A7I2V4N1_HUMAN,tr|A0A7I2V4I6|A0A7I2V4I6_HUMAN,tr|A0A087WUI2|A0A087WUI2_HUMAN,tr|A0A7I2V4S4|A0A7I2V4S4_HUMAN,tr|A0A7I2V323|A0A7I2V323_HUMAN,tr|A0A7I2V3P1|A0A7I2V3P1_HUMAN,tr|A0A7I2V3P7|A0A7I2V3P7_HUMAN" 10 1702.7719 1.17 147692 19909 3 1702.775299 568.5979 Heterogeneous nuclear ribonucleoproteins A2\B1 OS=Homo sapiens OX=9606 GN=HNRNPA2B1 PE=1 SV=2 4.13 3443.2 - 80448.6 - - - 2.0249 - 1.104 0.293 - 55.5 1 2 0 0.0034 15 0 0 0 4.26E+06 3.63E+06 - - - 2.0639 1 221125_WJC_METTL3_EV_vs_WT_F10.19915.19915.4 2.33E-08 16/186 K.SIDDTSNFDEFPESDILK[136.11]PTVATSNHPETDYK[136.11].N sp|Q15208|STK38_HUMAN 1 3627.6711 4.33 147696 19915 4 3627.674693 907.9251 Serine\threonine-protein kinase 38 OS=Homo sapiens OX=9606 GN=STK38 PE=1 SV=1 4.02 3444 - 368538 - - - 0.9772 - 3.119 0.617 - 87.7 1 2 0 0.0035 32 0 0 0 4.01E+07 9.27E+06 - - - 4.9388 0.9999 221125_WJC_METTL3_EV_vs_WT_F10.19916.19916.3 1.11E-07 Oct-56 R.GFGFVTFDDHDPVDK.L "sp|P22626|ROA2_HUMAN,tr|A0A7I2V4N0|A0A7I2V4N0_HUMAN,tr|A0A024RA28|A0A024RA28_HUMAN,tr|A0A7I2V4N1|A0A7I2V4N1_HUMAN,tr|A0A7I2V4I6|A0A7I2V4I6_HUMAN,tr|A0A087WUI2|A0A087WUI2_HUMAN,tr|A0A7I2V4S4|A0A7I2V4S4_HUMAN,tr|A0A7I2V323|A0A7I2V323_HUMAN,tr|A0A7I2V3P1|A0A7I2V3P1_HUMAN,tr|A0A7I2V3P7|A0A7I2V3P7_HUMAN" 10 1694.7577 1.17 147697 19916 3 1694.762078 565.9265 Heterogeneous nuclear ribonucleoproteins A2\B1 OS=Homo sapiens OX=9606 GN=HNRNPA2B1 PE=1 SV=2 4.13 3444.2 - 150786 - - - 2.6122 - 2.286 0.585 - 71.4 1 2 0 0.0044 15 0 0 0 4.26E+06 3.63E+06 - - - 7.2184 0.9965 221125_WJC_METTL3_EV_vs_WT_F10.19920.19920.2 0.00674 26-May R.FTQAGSEVSALLGR.L "sp|P06576|ATPB_HUMAN,tr|F8W0P7|F8W0P7_HUMAN,tr|H0YH81|H0YH81_HUMAN" 3 1434.7467 16.9 147699 19920 2 1434.749298 718.3806 "ATP synthase subunit beta, mitochondrial OS=Homo sapiens OX=9606 GN=ATP5F1B PE=1 SV=3" 6 3444.7 - 56345.4 - - - 1.8157 - 1.136 0.348 - 67.2 1 2 0 0.0026 14 0 0 0 1.33E+06 7.86E+04 - - - 1.9305 1 221125_WJC_METTL3_EV_vs_WT_F10.19926.19926.4 4.71E-06 14/108 K.K[136.11]ISSIQSIVPALEIANAHR[166.11].K "sp|P10809|CH60_HUMAN,tr|A0A7I2V2X6|A0A7I2V2X6_HUMAN,tr|A0A7I2YQK6|A0A7I2YQK6_HUMAN,tr|A0A7I2V599|A0A7I2V599_HUMAN,tr|A0A7I2YQ71|A0A7I2YQ71_HUMAN,tr|A0A7I2V5M1|A0A7I2V5M1_HUMAN,tr|A0A7I2V5K3|A0A7I2V5K3_HUMAN,tr|A0A7I2V369|A0A7I2V369_HUMAN" 8 2064.181 1.36 147703 19926 4 2064.180782 517.0525 "60 kDa heat shock protein, mitochondrial OS=Homo sapiens OX=9606 GN=HSPD1 PE=1 SV=2" 8.75 3445.6 - 170425 - - - -0.1264 - 2.634 0.587 - 140.3 1 2 0 -0.0003 19 0 0 0 1.34E+07 9.85E+06 - - - 4.6628 0.9998 221125_WJC_METTL3_EV_vs_WT_F10.19932.19932.2 0.000221 18-Jun R.EC[160.03]LNLWGYER[166.11].V sp|Q86U44|MTA70_HUMAN 1 1348.6109 0.01 147707 19932 2 1348.609638 675.3127 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 4.53 3446.4 - 62446.7 - - - -0.9662 - 1.452 0.548 - 166.7 1 2 0 -0.0013 10 0 0 0 1.96E+05 1.40E+07 - - - 4.1291 0.9999 221125_WJC_METTL3_EV_vs_WT_F10.19936.19936.3 5.10E-06 Oct-72 K.KISSIQSIVPALEIANAHR.K "sp|P10809|CH60_HUMAN,tr|A0A7I2V2X6|A0A7I2V2X6_HUMAN,tr|A0A7I2YQK6|A0A7I2YQK6_HUMAN,tr|A0A7I2V599|A0A7I2V599_HUMAN,tr|A0A7I2YQ71|A0A7I2YQ71_HUMAN,tr|A0A7I2V5M1|A0A7I2V5M1_HUMAN,tr|A0A7I2V5K3|A0A7I2V5K3_HUMAN,tr|A0A7I2V369|A0A7I2V369_HUMAN" 8 2046.1586 1.47 147709 19936 3 2046.164406 683.0601 "60 kDa heat shock protein, mitochondrial OS=Homo sapiens OX=9606 GN=HSPD1 PE=1 SV=2" 8.75 3447 - 74124.9 - - - 2.8507 - 2.212 0.52 - 108 1 2 0 0.0058 19 0 0 0 5.48E+06 3.74E+06 - - - 6.2863 0.9993 221125_WJC_METTL3_EV_vs_WT_F10.19941.19941.3 0.00506 5/136 K.SVGSTQQTLENISNIAGNGSFSSPSSSHLPSENEK.Q sp|O94916|NFAT5_HUMAN 1 3589.6768 1.55 147712 19941 3 3589.678415 1197.5662 Nuclear factor of activated T-cells 5 OS=Homo sapiens OX=9606 GN=NFAT5 PE=1 SV=1 4.75 3447.7 - 48734.7 - - - 0.4382 - 1.178 0.42 - 10.9 1 2 0 0.0016 35 0 0 0 6.07E+05 3.92E+05 - - - 3.599 0.999 221125_WJC_METTL3_EV_vs_WT_F10.20004.20004.2 9.93E-05 22-Jul K.DAGTIAGLNVLR.L "sp|P11142|HSP7C_HUMAN,tr|E9PQQ4|E9PQQ4_HUMAN,tr|E9PKE3|E9PKE3_HUMAN,tr|E9PN89|E9PN89_HUMAN,tr|E9PLF4|E9PLF4_HUMAN,tr|E9PI65|E9PI65_HUMAN,tr|E9PK54|E9PK54_HUMAN,tr|E9PQK7|E9PQK7_HUMAN" 8 1198.667 4.16 147740 20004 2 1198.669991 600.3408 Heat shock cognate 71 kDa protein OS=Homo sapiens OX=9606 GN=HSPA8 PE=1 SV=1 5.84 3456.6 - 109696 - - - 2.507 - 1.637 0.432 - 165.6 1 2 0 0.003 12 0 0 0 3.17E+07 7.61E+06 - - - 3.5276 1 221125_WJC_METTL3_EV_vs_WT_F10.20011.20011.4 1.91E-12 15/192 R.AEQDSTTVAAFASSLVSGLNSSASEPAK[136.11]EPAK[136.11]K[136.11].S "sp|Q86U44|MTA70_HUMAN,tr|F5H6D8|F5H6D8_HUMAN,tr|H0YFV6|H0YFV6_HUMAN,tr|B4DTN4|B4DTN4_HUMAN" 4 3301.674 0.01 147742 20011 4 3302.67078 826.4258 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 4.87 3457.8 - 221594 - - - 301.9029 - 3.542 0.658 - 74.9 1 2 1 0.9968 33 0 0 0 1.59E+05 3.04E+07 - - - 5.0566 0.9999 221125_WJC_METTL3_EV_vs_WT_F10.20018.20018.2 6.61E-07 22-Oct K.DAGTIAGLNVLR[166.11].L "sp|P11142|HSP7C_HUMAN,tr|E9PQQ4|E9PQQ4_HUMAN,tr|E9PKE3|E9PKE3_HUMAN,tr|E9PN89|E9PN89_HUMAN,tr|E9PLF4|E9PLF4_HUMAN,tr|E9PI65|E9PI65_HUMAN,tr|E9PK54|E9PK54_HUMAN,tr|E9PQK7|E9PQK7_HUMAN" 8 1208.6753 4.16 147746 20018 2 1208.674671 605.3449 Heat shock cognate 71 kDa protein OS=Homo sapiens OX=9606 GN=HSPA8 PE=1 SV=1 5.84 3458.9 - 114754 - - - -0.484 - 2.288 0.5 - 341.3 1 2 0 -0.0006 12 0 0 0 3.17E+07 7.61E+06 - - - 4.9116 0.9988 221125_WJC_METTL3_EV_vs_WT_F10.20036.20036.3 1.34E-07 11/136 R.TPGNC[160.03]QNSANEVDLLGPNQNGSEGLAQLTSTNGAK.P "sp|Q14671|PUM1_HUMAN,tr|Q5T1Z8|Q5T1Z8_HUMAN,tr|H0YDK8|H0YDK8_HUMAN,tr|H0YEH2|H0YEH2_HUMAN,tr|Q5T1Z4|Q5T1Z4_HUMAN,tr|H0YED4|H0YED4_HUMAN" 6 3555.6496 3.77 147753 20036 3 3555.653599 1186.2238 Pumilio homolog 1 OS=Homo sapiens OX=9606 GN=PUM1 PE=1 SV=3 4.14 3461.6 - 76649.8 - - - 1.1298 - 2.747 0.673 - 82.5 1 1 0 0.004 35 0 0 0 3.51E+06 9.32E+05 - - - 8.367 1 221125_WJC_METTL3_EV_vs_WT_F10.20047.20047.4 8.34E-09 14/204 R.TPGNC[160.03]QNSANEVDLLGPNQNGSEGLAQLTSTNGAK.P "sp|Q14671|PUM1_HUMAN,tr|Q5T1Z8|Q5T1Z8_HUMAN,tr|H0YDK8|H0YDK8_HUMAN,tr|H0YEH2|H0YEH2_HUMAN,tr|Q5T1Z4|Q5T1Z4_HUMAN,tr|H0YED4|H0YED4_HUMAN" 6 3555.6496 3.95 147757 20047 4 3555.651478 889.9197 Pumilio homolog 1 OS=Homo sapiens OX=9606 GN=PUM1 PE=1 SV=3 4.14 3463.3 - 103670 - - - 0.5332 - 2.26 0.648 - 74.1 1 1 0 0.0019 35 0 0 0 1.75E+06 4.44E+05 - - - 5.1074 1 221125_WJC_METTL3_EV_vs_WT_F10.20067.20067.4 1.35E-07 14/198 R.SDSPVPTAPTSGGPK[136.11]PSTASAVPELATDPELEK[136.11]K[136.11].L "sp|Q86U44|MTA70_HUMAN,tr|B4E349|B4E349_HUMAN,tr|F5H6D8|F5H6D8_HUMAN,tr|B4DTN4|B4DTN4_HUMAN" 4 3384.7363 0 147765 20067 4 3384.739276 847.1913 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 4.51 3466.4 - 402479 - - - 0.8908 - 3.035 0.513 - 72.6 1 2 0 0.003 34 0 0 0 4.34E+04 3.81E+07 - - - 4.0214 0.9999 221125_WJC_METTL3_EV_vs_WT_F10.20077.20077.3 1.04E-05 Sep-48 R.KVESLQEEIAFLK.K "sp|P08670|VIME_HUMAN,tr|B0YJC5|B0YJC5_HUMAN,tr|B0YJC4|B0YJC4_HUMAN" 3 1532.845 1.34 147768 20077 3 1532.847513 511.9556 Vimentin OS=Homo sapiens OX=9606 GN=VIM PE=1 SV=4 4.79 3468 - 71423.1 - - - 1.6329 - 2.026 0.458 - 160 1 2 0 0.0025 13 0 0 0 3.77E+06 2.82E+06 - - - 5.5599 0.9997 221125_WJC_METTL3_EV_vs_WT_F10.20082.20082.2 0.0104 22-Jul K.WELLQQVDTSTR.T sp|P04264|K2C1_HUMAN 1 1474.7416 89.8 147771 20082 2 1474.74079 738.3781 "Keratin, type II cytoskeletal 1 OS=Homo sapiens OX=9606 GN=KRT1 PE=1 SV=6" 4.37 3468.7 - 60287.6 - - - -0.554 - 1.955 0.39 - 169.6 1 2 0 -0.0008 12 0 0 0 7.51E+06 8.37E+04 - - - 3.6852 0.9945 221125_WJC_METTL3_EV_vs_WT_F10.20096.20096.4 0.00314 9/120 R.K[136.11]HAASDVDLEIESLLNQQSTK[136.11].E "sp|Q86U44|MTA70_HUMAN,tr|F5H6D8|F5H6D8_HUMAN,tr|H0YFV6|H0YFV6_HUMAN,tr|B4DTN4|B4DTN4_HUMAN" 4 2341.2096 0.04 147774 20096 4 2342.210991 586.3097 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 4.75 3470.9 - 111256 - - - 427.7157 - 2.157 0.407 - 59.2 1 2 0 1.0014 21 0 0 0 1.04E+05 2.69E+06 - - - 2.7453 0.9976 221125_WJC_METTL3_EV_vs_WT_F10.20109.20109.2 0.00113 16-Jul K.LLQDFFNGK[136.11].E "sp|P54652|HSP72_HUMAN,sp|P11142|HSP7C_HUMAN,sp|P17066|HSP76_HUMAN,tr|E9PNE6|E9PNE6_HUMAN,tr|A8K7Q2|A8K7Q2_HUMAN,tr|E9PKE3|E9PKE3_HUMAN,tr|E9PN89|E9PN89_HUMAN" 7 1088.5746 0.27 147781 20109 2 1088.578389 545.2946 Heat shock-related 70 kDa protein 2 OS=Homo sapiens OX=9606 GN=HSPA2 PE=1 SV=1 5.84 3472.8 - 125914 - - - 3.4853 - 1.307 0.476 - 121.3 1 2 0 0.0038 9 0 0 0 1.38E+06 5.09E+06 - - - 3.3301 0.9991 221125_WJC_METTL3_EV_vs_WT_F10.20118.20118.4 0.00849 8/150 R.TGHILHPEYLQPLPSTPVSPIELDAK.K sp|Q96F45|ZN503_HUMAN 1 2851.512 2.91 147786 20118 4 2851.51942 713.8853 Zinc finger protein 503 OS=Homo sapiens OX=9606 GN=ZNF503 PE=1 SV=1 5.26 3474 - 47555.1 - - - 2.6035 - 1.943 0.352 - 31.6 1 2 0 0.0074 26 0 0 0 9.38E+05 3.23E+05 - - - 2.4973 0.9936 221125_WJC_METTL3_EV_vs_WT_F10.20146.20146.4 0.0615 5/144 K.KVEHEISEGNVATAAAAALASAATK.A sp|Q92922|SMRC1_HUMAN 1 2409.25 11.58 147802 20146 4 2409.250651 603.3198 SWI\SNF complex subunit SMARCC1 OS=Homo sapiens OX=9606 GN=SMARCC1 PE=1 SV=3 5.5 3477.9 - 56659.8 - - - 0.2839 - 1.196 0.235 - 10.4 1 2 0 0.0007 25 0 0 0 2.07E+06 1.78E+05 - - - 1.3282 0.9657 221125_WJC_METTL3_EV_vs_WT_F10.20189.20189.3 0.0192 Aug-52 Q.LDGIHLLDPDVVAR[166.11].F sp|Q86U44|MTA70_HUMAN 1 1541.8441 0 147818 20189 3 1541.843569 514.9553 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 4.41 3483.9 - 114248 - - - -0.3522 - 1.976 0.339 - 74 1 1 0 -0.0005 14 0 0 0 4.07E+04 8.86E+06 - - - 4.1293 1 221125_WJC_METTL3_EV_vs_WT_F10.20210.20210.2 2.02E-10 13/38 K.GNPQGFNQGLDC[160.03]DVIVAEVR[166.11].S sp|Q86U44|MTA70_HUMAN 1 2197.0461 0.001 147827 20210 2 2198.044768 1099.5303 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 4.03 3486.9 - 139350 - - - 454.5339 - 2.66 0.657 - 370.2 1 2 0 0.9986 20 0 0 0 0.00E+00 2.26E+07 - - - 5.9853 0.9986 221125_WJC_METTL3_EV_vs_WT_F10.20225.20225.3 4.82E-07 Oct-76 K.GNPQGFNQGLDC[160.03]DVIVAEVR.S sp|Q86U44|MTA70_HUMAN 1 2187.0379 0.02 147835 20225 3 2188.037506 730.0199 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 4.03 3488.9 - 61252.5 - - - 457.0748 - 2.085 0.571 - 121.9 1 2 0 0.9996 20 0 0 0 3.27E+06 1.68E+08 - - - 6.4117 1 221125_WJC_METTL3_EV_vs_WT_F10.20240.20240.3 1.28E-07 14/124 R.GGGGSFGYSYGGGSGGGFSASSLGGGFGGGSR.G sp|P35527|K1C9_HUMAN 1 2704.1538 999 147841 20240 3 2704.148701 902.3919 "Keratin, type I cytoskeletal 9 OS=Homo sapiens OX=9606 GN=KRT9 PE=1 SV=3" 8.59 3491.2 - 227833 - - - -1.8986 - 2.494 0.67 - 97.8 1 2 0 -0.0051 32 0 0 0 4.16E+06 0.00E+00 - - - 8.1109 1 221125_WJC_METTL3_EV_vs_WT_F10.20248.20248.4 1.24E-12 17/198 K.DVHKGESGSQEGGVNSFSTLIGLPSTSAVTSQPK.S sp|P55197|AF10_HUMAN 1 3400.6747 4.06 147845 20248 4 3400.673326 851.1759 Protein AF-10 OS=Homo sapiens OX=9606 GN=MLLT10 PE=1 SV=2 5.45 3492.3 - 347674 - - - -0.3914 - 3.797 0.704 - 86.5 1 2 1 -0.0013 34 0 0 0 2.47E+07 6.09E+06 - - - 5.7511 1 221125_WJC_METTL3_EV_vs_WT_F10.20264.20264.4 3.37E-10 15/198 K.DVHK[136.11]GESGSQEGGVNSFSTLIGLPSTSAVTSQPK[136.11].S sp|P55197|AF10_HUMAN 1 3416.7031 4.06 147853 20264 4 3416.701377 855.183 Protein AF-10 OS=Homo sapiens OX=9606 GN=MLLT10 PE=1 SV=2 5.45 3494.4 - 249802 - - - -0.4917 - 3.543 0.68 - 71 1 2 1 -0.0017 34 0 0 0 2.47E+07 6.09E+06 - - - 5.5215 1 221125_WJC_METTL3_EV_vs_WT_F10.20285.20285.4 5.44E-06 15/198 R.SDSPVPTAPTSGGPK[136.11]PSTASAVPELATDPELEK[136.11]K[136.11].L "sp|Q86U44|MTA70_HUMAN,tr|B4E349|B4E349_HUMAN,tr|F5H6D8|F5H6D8_HUMAN,tr|B4DTN4|B4DTN4_HUMAN" 4 3384.7363 0.01 147862 20285 4 3384.741076 847.1913 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 4.51 3497.4 - 387572 - - - 1.4226 - 2.977 0.499 - 85.3 1 2 0 0.0048 34 0 0 0 1.04E+05 1.74E+07 - - - 3.8933 0.9999 221125_WJC_METTL3_EV_vs_WT_F10.20292.20292.4 8.66E-10 11/192 R.R[166.11]PHDYQPLPGMSENPSVYVPGVVSTVVPDSAHK[136.11].L "sp|P26368|U2AF2_HUMAN,tr|K7ENG2|K7ENG2_HUMAN" 2 3576.779 0.94 147865 20292 4 3576.76822 895.202 Splicing factor U2AF 65 kDa subunit OS=Homo sapiens OX=9606 GN=U2AF2 PE=1 SV=4 6 3498.4 - 70458.4 - - - -3.0203 - 2.593 0.59 - 49 1 2 0 -0.0108 33 0 0 0 2.11E+06 2.23E+06 - - - 4.6442 0.9963 221125_WJC_METTL3_EV_vs_WT_F10.20294.20294.3 0.234 Apr-80 R.VIISAPSADAPMFVMGVNHEK.Y "sp|P04406|G3P_HUMAN,tr|E7EUT5|E7EUT5_HUMAN" 2 2212.102 1.41 147866 20294 3 2212.105165 738.3746 Glyceraldehyde-3-phosphate dehydrogenase OS=Homo sapiens OX=9606 GN=GAPDH PE=1 SV=3 5.32 3498.7 - 79172.8 - - - 1.41 - 1.084 0.35 - 15.9 1 2 0 0.0031 21 0 0 0 2.64E+06 1.88E+06 - - - 2.6347 0.9997 221125_WJC_METTL3_EV_vs_WT_F10.20301.20301.3 0.00454 Apr-80 R.VIISAPSADAPMFVMGVNHEK[136.11].Y "sp|P04406|G3P_HUMAN,tr|E7EUT5|E7EUT5_HUMAN" 2 2220.1162 1.39 147870 20301 3 2220.120113 741.046 Glyceraldehyde-3-phosphate dehydrogenase OS=Homo sapiens OX=9606 GN=GAPDH PE=1 SV=3 5.32 3499.7 - 78570.1 - - - 1.7418 - 1.254 0.493 - 11.8 1 2 0 0.0039 21 0 0 0 2.61E+06 1.88E+06 - - - 4.578 1 221125_WJC_METTL3_EV_vs_WT_F10.20306.20306.4 1.04E-06 12/192 R.RPHDYQPLPGMSENPSVYVPGVVSTVVPDSAHK.L "sp|P26368|U2AF2_HUMAN,tr|K7ENG2|K7ENG2_HUMAN" 2 3558.7566 0.94 147873 20306 4 3558.761912 890.6964 Splicing factor U2AF 65 kDa subunit OS=Homo sapiens OX=9606 GN=U2AF2 PE=1 SV=4 6 3500.4 - 59913 - - - 1.5059 - 2.922 0.554 - 58 1 2 0 0.0054 33 0 0 0 2.11E+06 2.23E+06 - - - 4.3682 0.9999 221125_WJC_METTL3_EV_vs_WT_F10.20307.20307.2 8.59E-08 20-Aug K.GFAFVQYVNER.N "sp|P07910|HNRPC_HUMAN,tr|G3V251|G3V251_HUMAN,tr|B4DY08|B4DY08_HUMAN,tr|G3V575|G3V575_HUMAN,tr|B4DSU6|B4DSU6_HUMAN,tr|G3V3K6|G3V3K6_HUMAN,tr|B2R5W2|B2R5W2_HUMAN,tr|G3V4C1|G3V4C1_HUMAN,tr|G3V576|G3V576_HUMAN,tr|G3V5X6|G3V5X6_HUMAN,tr|G3V4W0|G3V4W0_HUMAN,tr|G3V555|G3V555_HUMAN,tr|G3V4M8|G3V4M8_HUMAN,tr|G3V2Q1|G3V2Q1_HUMAN" 14 1328.6513 1.57 147874 20307 2 1328.649463 665.3329 Heterogeneous nuclear ribonucleoproteins C1\C2 OS=Homo sapiens OX=9606 GN=HNRNPC PE=1 SV=4 6 3500.5 - 64726.8 - - - -1.4097 - 2.051 0.622 - 228.9 1 2 0 -0.0019 11 0 0 0 2.00E+06 1.27E+06 - - - 5.5777 0.9796 221125_WJC_METTL3_EV_vs_WT_F10.20331.20331.4 2.37E-06 12/120 R.K[136.11]HAASDVDLEIESLLNQQSTK[136.11].E "sp|Q86U44|MTA70_HUMAN,tr|F5H6D8|F5H6D8_HUMAN,tr|H0YFV6|H0YFV6_HUMAN,tr|B4DTN4|B4DTN4_HUMAN" 4 2341.2096 0.02 147885 20331 4 2342.204376 586.3097 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 4.75 3504.1 - 130037 - - - 424.8902 - 2.845 0.43 - 129.3 1 2 0 0.9948 21 0 0 0 8.29E+04 3.66E+06 - - - 3.0389 0.9991 221125_WJC_METTL3_EV_vs_WT_F10.20341.20341.2 0.00157 22-Sep K.SLNNQFASFIDK.V sp|P04264|K2C1_HUMAN 1 1382.683 46.06 147889 20341 2 1382.6879 692.3488 "Keratin, type II cytoskeletal 1 OS=Homo sapiens OX=9606 GN=KRT1 PE=1 SV=6" 5.55 3505.6 - 45663.2 - - - 3.5221 - 1.918 0.539 - 276.4 1 2 0 0.0049 12 0 0 0 1.67E+07 3.63E+05 - - - 4.7342 0.9998 221125_WJC_METTL3_EV_vs_WT_F10.20347.20347.4 7.70E-05 6/192 R.AEQDSTTVAAFASSLVSGLNSSASEPAK[136.11]EPAK[136.11]K[136.11].S "sp|Q86U44|MTA70_HUMAN,tr|F5H6D8|F5H6D8_HUMAN,tr|H0YFV6|H0YFV6_HUMAN,tr|B4DTN4|B4DTN4_HUMAN" 4 3301.674 0.7 147892 20347 4 3301.668877 826.4258 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 4.87 3506.3 - 60945.7 - - - -1.5501 - 1.37 0.506 - 17 1 2 1 -0.0051 33 0 0 0 2.44E+06 3.48E+06 - - - 3.7233 0.9981 221125_WJC_METTL3_EV_vs_WT_F10.20375.20375.2 0.0753 14-Jun K.DVIEEYFK.C sp|P25398|RS12_HUMAN 1 1041.5019 2.12 147904 20375 2 1041.502141 521.7582 40S ribosomal protein S12 OS=Homo sapiens OX=9606 GN=RPS12 PE=1 SV=3 4.14 3510.5 - 85877.4 - - - 0.2525 - 1.215 0.304 - 123.4 1 2 0 0.0003 8 0 0 0 1.63E+06 7.69E+05 - - - 1.8736 1 221125_WJC_METTL3_EV_vs_WT_F10.20392.20392.3 1.20E-05 Sep-96 K.IDSIPHLNNSTPLVDPSVYGYGVQK.R sp|Q96I24|FUBP3_HUMAN 1 2712.3759 2.74 147915 20392 3 2712.378217 905.1326 Far upstream element-binding protein 3 OS=Homo sapiens OX=9606 GN=FUBP3 PE=1 SV=2 5.21 3512.9 - 90487.9 - - - 0.8557 - 2.183 0.516 - 63.3 1 2 0 0.0023 25 0 0 0 3.95E+06 1.44E+06 - - - 6.0884 0.8346 221125_WJC_METTL3_EV_vs_WT_F10.20393.20393.4 0.0241 5/144 K.HAASDVDLEIESLLNQQSTK[136.11]EQQSK[136.11].K "sp|Q86U44|MTA70_HUMAN,tr|F5H6D8|F5H6D8_HUMAN,tr|H0YFV6|H0YFV6_HUMAN,tr|B4DTN4|B4DTN4_HUMAN" 4 2813.4014 0.01 147916 20393 4 2814.401239 704.3576 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 4.5 3513 - 41050.4 - - - 355.3858 - 0.91 0.335 - 9.2 1 2 1 0.9998 25 0 0 0 9.05E+04 1.11E+07 - - - 1.8349 0.9997 221125_WJC_METTL3_EV_vs_WT_F10.20409.20409.2 0.000644 16-Jul K.LLQDFFNGR[166.11].D "sp|P0DMV8|HS71A_HUMAN,sp|P0DMV9|HS71B_HUMAN,tr|V9GZ37|V9GZ37_HUMAN,tr|A0A0G2JIW1|A0A0G2JIW1_HUMAN" 4 1118.5748 45.93 147924 20409 2 1118.574603 560.2947 Heat shock 70 kDa protein 1A OS=Homo sapiens OX=9606 GN=HSPA1A PE=1 SV=1 5.84 3515.1 - 140107 - - - -0.1877 - 1.403 0.499 - 154.6 1 2 0 -0.0002 9 0 0 0 3.23E+08 7.04E+06 - - - 3.7062 0.9932 221125_WJC_METTL3_EV_vs_WT_F10.20410.20410.3 0.0845 Apr-96 K.IDSIPHLNNSTPLVDPSVYGYGVQK[136.11].R sp|Q96I24|FUBP3_HUMAN 1 2720.3901 2.74 147925 20410 3 2720.389184 907.804 Far upstream element-binding protein 3 OS=Homo sapiens OX=9606 GN=FUBP3 PE=1 SV=2 5.21 3515.3 - 80702.1 - - - -0.3352 - 1.109 0.293 - 10.7 1 2 0 -0.0009 25 0 0 0 3.95E+06 1.44E+06 - - - 2.0444 0.9082 221125_WJC_METTL3_EV_vs_WT_F10.20426.20426.2 0.287 14-Jun Y.LFALGVYR.T sp|P24390|ERD21_HUMAN 1 937.5385 87.24 147930 20426 2 937.537984 469.7765 ER lumen protein-retaining receptor 1 OS=Homo sapiens OX=9606 GN=KDELR1 PE=1 SV=1 8.75 3517.8 - 93457.1 - - - -0.5909 - 1.467 0.24 - 124.7 1 1 0 -0.0006 8 0 0 0 9.36E+06 1.07E+05 - - - 1.9692 0.945 221125_WJC_METTL3_EV_vs_WT_F10.20432.20432.3 0.000504 Jul-96 K.HAASDVDLEIESLLNQQSTK[136.11]EQQSK[136.11].K "sp|Q86U44|MTA70_HUMAN,tr|F5H6D8|F5H6D8_HUMAN,tr|H0YFV6|H0YFV6_HUMAN,tr|B4DTN4|B4DTN4_HUMAN" 4 2813.4014 0.001 147933 20432 3 2814.3974 938.8077 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 4.5 3518.6 - 48286.6 - - - 354.0213 - 1.562 0.493 - 27.3 1 2 1 0.996 25 0 0 0 0.00E+00 8.42E+05 - - - 4.7866 1 221125_WJC_METTL3_EV_vs_WT_F10.20459.20459.2 2.27E-09 16/40 R.K[136.11]HAASDVDLEIESLLNQQSTK[136.11].E "sp|Q86U44|MTA70_HUMAN,tr|F5H6D8|F5H6D8_HUMAN,tr|H0YFV6|H0YFV6_HUMAN,tr|B4DTN4|B4DTN4_HUMAN" 4 2341.2096 0.001 147942 20459 2 2341.200615 1171.6121 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 4.75 3522.5 - 162049 - - - -3.8459 - 3.487 0.647 - 497.3 1 2 0 -0.009 21 0 0 0 0.00E+00 1.11E+07 - - - 6.8877 0.9991 221125_WJC_METTL3_EV_vs_WT_F10.20495.20495.4 3.90E-07 14/198 R.SDSPVPTAPTSGGPK[136.11]PSTASAVPELATDPELEK[136.11]K[136.11].L "sp|Q86U44|MTA70_HUMAN,tr|B4E349|B4E349_HUMAN,tr|F5H6D8|F5H6D8_HUMAN,tr|B4DTN4|B4DTN4_HUMAN" 4 3384.7363 0.02 147953 20495 4 3384.721198 847.1913 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 4.51 3527.4 - 757338 - - - -4.4503 - 2.867 0.419 - 64.1 1 2 0 -0.0151 34 0 0 0 6.34E+05 3.73E+07 - - - 3.1829 0.9993 221125_WJC_METTL3_EV_vs_WT_F10.20525.20525.4 2.04E-06 26/138 K.QISNLQQSISDAEQRGENALKDAK.N sp|P04264|K2C1_HUMAN 1 2642.326 999 147957 20525 4 2642.314838 661.5888 "Keratin, type II cytoskeletal 1 OS=Homo sapiens OX=9606 GN=KRT1 PE=1 SV=6" 4.78 3532.3 - 890372 - - - -4.219 - 3.651 0.538 - 350.9 1 2 2 -0.0111 24 0 0 0 6.16E+07 0.00E+00 - - - 4.3213 0.9978 221125_WJC_METTL3_EV_vs_WT_F10.20549.20549.3 0.000196 Oct-92 K.QISNLQQSISDAEQRGENALKDAK.N sp|P04264|K2C1_HUMAN 1 2642.326 999 147963 20549 3 2642.318952 881.7826 "Keratin, type II cytoskeletal 1 OS=Homo sapiens OX=9606 GN=KRT1 PE=1 SV=6" 4.78 3535.8 - 257307 - - - -2.662 - 2.098 0.401 - 84.7 1 2 2 -0.007 24 0 0 0 5.40E+06 0.00E+00 - - - 4.7298 1 221125_WJC_METTL3_EV_vs_WT_F10.20560.20560.4 7.95E-14 23/192 R.AEQDSTTVAAFASSLVSGLNSSASEPAK[136.11]EPAK[136.11]K[136.11].S "sp|Q86U44|MTA70_HUMAN,tr|F5H6D8|F5H6D8_HUMAN,tr|H0YFV6|H0YFV6_HUMAN,tr|B4DTN4|B4DTN4_HUMAN" 4 3301.674 0.05 147968 20560 4 3301.657972 826.4258 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 4.87 3537.2 - 410856 - - - -4.853 - 4.005 0.697 - 118.8 1 2 1 -0.016 33 0 0 0 3.24E+05 6.28E+06 - - - 5.7046 0.9941 221125_WJC_METTL3_EV_vs_WT_F10.20569.20569.3 0.00038 Aug-44 K.IEEIK[136.11]DFLLTAR[166.11].R "sp|P63173|RL38_HUMAN,tr|J3KT73|J3KT73_HUMAN,tr|J3QL01|J3QL01_HUMAN,tr|J3KSP2|J3KSP2_HUMAN" 4 1464.8307 2.28 147972 20569 3 1464.827534 489.2842 60S ribosomal protein L38 OS=Homo sapiens OX=9606 GN=RPL38 PE=1 SV=2 4.68 3538.5 - 126647 - - - -2.1613 - 1.488 0.359 - 77.6 1 2 1 -0.0032 12 0 0 0 6.37E+06 2.79E+06 - - - 3.6432 1 221125_WJC_METTL3_EV_vs_WT_F10.20596.20596.4 2.47E-11 23/120 R.K[136.11]HAASDVDLEIESLLNQQSTK[136.11].E "sp|Q86U44|MTA70_HUMAN,tr|F5H6D8|F5H6D8_HUMAN,tr|H0YFV6|H0YFV6_HUMAN,tr|B4DTN4|B4DTN4_HUMAN" 4 2341.2096 0.01 147985 20596 4 2341.205527 586.3097 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 4.75 3542 - 1.19E+06 - - - -1.7478 - 4.304 0.586 - 419.4 1 2 0 -0.0041 21 0 0 0 6.37E+07 4.32E+09 - - - 4.808 0.9999 221125_WJC_METTL3_EV_vs_WT_F10.20633.20633.4 2.23E-11 17/288 R.DSSKGEDSAEETEAKPAVVAPAPVVEAVSTPSAAFPSDATAEQGPILTK.H sp|Q12906|ILF3_HUMAN 1 4851.3826 1.53 148005 20633 4 4851.393887 1213.8529 Interleukin enhancer-binding factor 3 OS=Homo sapiens OX=9606 GN=ILF3 PE=1 SV=3 4.06 3547.4 - 113724 - - - 2.334 - 3.404 0.597 - 54 1 2 1 0.0113 49 0 0 0 1.21E+07 7.93E+06 - - - 4.7592 0.994 221125_WJC_METTL3_EV_vs_WT_F10.20644.20644.2 0.037 26-Apr K.NIYVLQELDNPGAK[136.11].R "sp|P12956|XRCC6_HUMAN,tr|B1AHC9|B1AHC9_HUMAN" 2 1580.829 0.6 148010 20644 2 1580.831499 791.4218 X-ray repair cross-complementing protein 6 OS=Homo sapiens OX=9606 GN=XRCC6 PE=1 SV=2 4.37 3549 - 28863.7 - - - 1.5985 - 1.044 0.305 - 43.1 1 2 0 0.0025 14 0 0 0 8.27E+05 1.38E+06 - - - 1.401 1 221125_WJC_METTL3_EV_vs_WT_F10.20656.20656.3 9.49E-08 18/80 R.K[136.11]HAASDVDLEIESLLNQQSTK[136.11].E "sp|Q86U44|MTA70_HUMAN,tr|F5H6D8|F5H6D8_HUMAN,tr|H0YFV6|H0YFV6_HUMAN,tr|B4DTN4|B4DTN4_HUMAN" 4 2341.2096 0.07 148016 20656 3 2341.212537 781.4105 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 4.75 3550.6 - 262403 - - - 1.2464 - 3.453 0.542 - 409.4 1 2 0 0.0029 21 0 0 0 1.88E+06 2.67E+07 - - - 7.553 0.993 221125_WJC_METTL3_EV_vs_WT_F10.20665.20665.2 0.334 14-May R.LTILELER[166.11].E sp|Q569K6|CC157_HUMAN 1 995.5891 0 148020 20665 2 995.589807 498.8018 Coiled-coil domain-containing protein 157 OS=Homo sapiens OX=9606 GN=CCDC157 PE=1 SV=3 4.53 3551.9 - 46312.1 - - - 0.7433 - 1.154 0.205 - 101.7 1 2 0 0.0007 8 0 0 0 4.12E+04 5.54E+07 - - - 0.9869 0.9999 221125_WJC_METTL3_EV_vs_WT_F10.20705.20705.4 0.000488 6/144 K.GDTNIK[136.11]PILQVINIR[166.11]PITTGNSPPR[166.11].Y "sp|P27694|RFA1_HUMAN,tr|I3L2M5|I3L2M5_HUMAN,tr|I3L524|I3L524_HUMAN" 3 2741.5546 1.25 148039 20705 4 2741.557327 686.3959 Replication protein A 70 kDa DNA-binding subunit OS=Homo sapiens OX=9606 GN=RPA1 PE=1 SV=2 10.84 3557.6 - 67875 - - - 0.9808 - 1.649 0.48 - 22 1 2 0 0.0027 25 0 0 0 5.64E+06 4.53E+06 - - - 3.5623 0.9819 221125_WJC_METTL3_EV_vs_WT_F10.20711.20711.3 0.134 Apr-60 R.IINEPTAAAIAYGLDR[166.11].T "sp|P0DMV8|HS71A_HUMAN,sp|P0DMV9|HS71B_HUMAN,sp|P17066|HSP76_HUMAN,tr|A0A0G2JIW1|A0A0G2JIW1_HUMAN" 4 1696.9024 0.14 148040 20711 3 1696.900525 566.6414 Heat shock 70 kDa protein 1A OS=Homo sapiens OX=9606 GN=HSPA1A PE=1 SV=1 4.37 3558.4 - 36252.1 - - - -1.0784 - 1.262 0.222 - 21.8 2 2 0 -0.0018 16 0 0 0 6.73E+05 4.87E+06 - - - 1.4723 1 221125_WJC_METTL3_EV_vs_WT_F10.20716.20716.4 6.88E-09 16/198 R.SDSPVPTAPTSGGPK[136.11]PSTASAVPELATDPELEK[136.11]K[136.11].L "sp|Q86U44|MTA70_HUMAN,tr|B4E349|B4E349_HUMAN,tr|F5H6D8|F5H6D8_HUMAN,tr|B4DTN4|B4DTN4_HUMAN" 4 3384.7363 0.01 148042 20716 4 3384.737156 847.1913 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 4.51 3559.2 - 296030 - - - 0.2644 - 2.987 0.558 - 101.4 1 2 0 0.0009 34 0 0 0 1.50E+05 2.10E+07 - - - 4.4089 0.9318 221125_WJC_METTL3_EV_vs_WT_F10.20718.20718.2 0.364 30-Jun R.DGLK[136.11]LMLLLEVISGER[166.11].L "sp|O43707|ACTN4_HUMAN,sp|P12814|ACTN1_HUMAN,tr|A0A804HK61|A0A804HK61_HUMAN,tr|A0A804HIN7|A0A804HIN7_HUMAN,tr|G3V5M4|G3V5M4_HUMAN,tr|A0A804HLF4|A0A804HLF4_HUMAN,tr|A0A804HIY0|A0A804HIY0_HUMAN,tr|A0A7I2V4Y4|A0A7I2V4Y4_HUMAN,tr|A0A804HII9|A0A804HII9_HUMAN,tr|A0A804HJQ9|A0A804HJQ9_HUMAN,tr|F5GXS2|F5GXS2_HUMAN,tr|A0A804HKE2|A0A804HKE2_HUMAN,tr|G3V2N5|G3V2N5_HUMAN,tr|A0A804HLD0|A0A804HLD0_HUMAN,tr|H7C144|H7C144_HUMAN" 15 1803.0295 0.001 148044 20718 2 1803.032783 902.522 Alpha-actinin-4 OS=Homo sapiens OX=9606 GN=ACTN4 PE=1 SV=2 4.68 3559.5 - 122006 - - - 1.8336 - 1.246 0.253 - 57.6 1 2 1 0.0033 16 0 0 0 0.00E+00 2.64E+06 - - - 1.4493 1 221125_WJC_METTL3_EV_vs_WT_F10.20721.20721.4 4.79E-08 18/228 K.TKKPGAGDTAFPGTGGFSATFDYQQAFGNSTGGFDGQAR.Q sp|Q96PK6|RBM14_HUMAN 1 3913.7932 1.64 148045 20721 4 3913.803059 979.4556 RNA-binding protein 14 OS=Homo sapiens OX=9606 GN=RBM14 PE=1 SV=2 5.71 3559.9 - 170499 - - - 2.5167 - 3.707 0.647 - 173 1 2 1 0.0098 39 0 0 0 4.69E+06 2.86E+06 - - - 5.2349 1 221125_WJC_METTL3_EV_vs_WT_F10.20723.20723.4 8.68E-09 9/228 K.TK[136.11]K[136.11]PGAGDTAFPGTGGFSATFDYQQAFGNSTGGFDGQAR[166.11].Q sp|Q96PK6|RBM14_HUMAN 1 3939.8299 1.62 148046 20723 4 3939.828813 985.9647 RNA-binding protein 14 OS=Homo sapiens OX=9606 GN=RBM14 PE=1 SV=2 5.71 3560.1 - 94291 - - - -0.2706 - 2.339 0.688 - 31.3 1 2 1 -0.0011 39 0 0 0 4.65E+06 2.86E+06 - - - 5.4606 0.9998 221125_WJC_METTL3_EV_vs_WT_F10.20726.20726.2 4.95E-06 30-Jun K.SYELPDGQVITIGNER.F "sp|Q6S8J3|POTEE_HUMAN,sp|P63261|ACTG_HUMAN,sp|P68133|ACTS_HUMAN,sp|P62736|ACTA_HUMAN,sp|Q9BYX7|ACTBM_HUMAN,sp|P68032|ACTC_HUMAN,sp|Q562R1|ACTBL_HUMAN,sp|P60709|ACTB_HUMAN,sp|P63267|ACTH_HUMAN,sp|A5A3E0|POTEF_HUMAN,tr|A0A804GS07|A0A804GS07_HUMAN,tr|E7EVS6|E7EVS6_HUMAN,tr|A0A6Q8PFE4|A0A6Q8PFE4_HUMAN,tr|A0A2R8YEA7|A0A2R8YEA7_HUMAN,tr|A0A804HKV3|A0A804HKV3_HUMAN,tr|A0A2R8Y793|A0A2R8Y793_HUMAN,tr|I3L4N8|I3L4N8_HUMAN,tr|A6NL76|A6NL76_HUMAN" 18 1789.8846 60.95 148049 20726 2 1789.88154 895.9496 POTE ankyrin domain family member E OS=Homo sapiens OX=9606 GN=POTEE PE=2 SV=3 4.14 3560.5 - 33307.5 - - - -1.7336 - 1.632 0.622 - 91.4 1 2 0 -0.0031 16 0 0 0 6.69E+06 1.10E+05 - - - 4.8383 0.9178 221125_WJC_METTL3_EV_vs_WT_F10.20736.20736.4 2.18E-06 10/132 L.SSQHRGDADQASNILASFGLSAR.D "sp|P43243|MATR3_HUMAN,tr|A8MXP9|A8MXP9_HUMAN,tr|D6R991|D6R991_HUMAN,tr|A0A0R4J2E8|A0A0R4J2E8_HUMAN,tr|D6REM6|D6REM6_HUMAN" 5 2387.1578 1.31 148052 20736 4 2387.165611 597.7967 Matrin-3 OS=Homo sapiens OX=9606 GN=MATR3 PE=1 SV=2 6.47 3562.2 - 116212 - - - 3.2729 - 2.003 0.483 - 74.1 1 1 1 0.0078 23 0 0 0 4.43E+06 3.38E+06 - - - 3.6529 1 221125_WJC_METTL3_EV_vs_WT_F10.20740.20740.4 1.28E-09 19/144 K.GDTNIKPILQVINIRPITTGNSPPR.Y "sp|P27694|RFA1_HUMAN,tr|I3L2M5|I3L2M5_HUMAN,tr|I3L524|I3L524_HUMAN" 3 2713.5239 1.25 148053 20740 4 2713.530306 679.3883 Replication protein A 70 kDa DNA-binding subunit OS=Homo sapiens OX=9606 GN=RPA1 PE=1 SV=2 10.84 3562.8 - 251162 - - - 2.3615 - 4.003 0.615 - 178.6 1 2 0 0.0064 25 0 0 0 5.64E+06 4.53E+06 - - - 5.0184 0.7903 221125_WJC_METTL3_EV_vs_WT_F10.20763.20763.3 0.0418 May-84 K.DSGPLPTPPGVSLLGEPPKDYR.L "tr|E9PAU2|E9PAU2_HUMAN,tr|A0A087WZ13|A0A087WZ13_HUMAN" 2 2291.1798 1.06 148064 20763 3 2291.184845 764.7339 Ribonucleoprotein PTB-binding 1 OS=Homo sapiens OX=9606 GN=RAVER1 PE=1 SV=1 4.56 3566 - 37002.8 - - - 2.2185 - 0.927 0.26 - 18.1 1 2 1 0.0051 22 0 0 0 1.74E+06 1.64E+06 - - - 1.2576 0.9982 221125_WJC_METTL3_EV_vs_WT_F10.20780.20780.3 0.00155 Jun-92 R.NGPGFHNDIDSNSTIQEILIPASK[136.11].V sp|Q96I24|FUBP3_HUMAN 1 2574.2805 2.67 148073 20780 3 2574.286854 859.1008 Far upstream element-binding protein 3 OS=Homo sapiens OX=9606 GN=FUBP3 PE=1 SV=2 4.54 3568.4 - 55228.5 - - - 2.4504 - 1.399 0.381 - 22.5 1 2 0 0.0063 24 0 0 0 4.81E+06 1.80E+06 - - - 3.5659 0.9027 221125_WJC_METTL3_EV_vs_WT_F10.20790.20790.2 0.233 18-Apr R.FEELC[160.03]SDLFR.S "sp|P48741|HSP77_HUMAN,sp|P0DMV8|HS71A_HUMAN,sp|P0DMV9|HS71B_HUMAN,sp|P17066|HSP76_HUMAN,tr|V9GZ37|V9GZ37_HUMAN,tr|A0A0G2JIW1|A0A0G2JIW1_HUMAN" 6 1314.5914 1.85 148080 20790 2 1314.594492 658.303 Putative heat shock 70 kDa protein 7 OS=Homo sapiens OX=9606 GN=HSPA7 PE=5 SV=2 4.14 3569.6 - 67534.3 - - - 2.3232 - 0.797 0.185 - 39.1 1 2 0 0.0031 10 0 0 0 1.75E+06 9.45E+05 - - - -0.2269 0.9997 221125_WJC_METTL3_EV_vs_WT_F10.20791.20791.3 0.00875 Sep-60 R.HGVQELEIELQSQLSK.K "sp|P35527|K1C9_HUMAN,tr|K7EQQ3|K7EQQ3_HUMAN" 2 1836.9581 786.53 148081 20791 3 1836.961231 613.3267 "Keratin, type I cytoskeletal 9 OS=Homo sapiens OX=9606 GN=KRT9 PE=1 SV=3" 4.75 3569.7 - 57021.2 - - - 1.6816 - 1.982 0.401 - 33.4 1 2 0 0.0031 16 0 0 0 6.35E+06 8.08E+03 - - - 4.7652 0.9977 221125_WJC_METTL3_EV_vs_WT_F10.20797.20797.3 0.0303 Jun-60 K.SYELPDGQVITIGNER.F "sp|Q6S8J3|POTEE_HUMAN,sp|P63261|ACTG_HUMAN,sp|P68133|ACTS_HUMAN,sp|P62736|ACTA_HUMAN,sp|Q9BYX7|ACTBM_HUMAN,sp|P68032|ACTC_HUMAN,sp|Q562R1|ACTBL_HUMAN,sp|P60709|ACTB_HUMAN,sp|P63267|ACTH_HUMAN,sp|A5A3E0|POTEF_HUMAN,tr|A0A804GS07|A0A804GS07_HUMAN,tr|E7EVS6|E7EVS6_HUMAN,tr|A0A6Q8PFE4|A0A6Q8PFE4_HUMAN,tr|A0A2R8YEA7|A0A2R8YEA7_HUMAN,tr|A0A804HKV3|A0A804HKV3_HUMAN,tr|A0A2R8Y793|A0A2R8Y793_HUMAN,tr|I3L4N8|I3L4N8_HUMAN,tr|A6NL76|A6NL76_HUMAN" 18 1789.8846 6.99 148084 20797 3 1789.886496 597.6355 POTE ankyrin domain family member E OS=Homo sapiens OX=9606 GN=POTEE PE=2 SV=3 4.14 3570.7 - 129834 - - - 1.0353 - 1.411 0.305 - 47.9 1 2 0 0.0019 16 0 0 0 4.11E+06 5.88E+05 - - - 2.8234 0.9712 221125_WJC_METTL3_EV_vs_WT_F10.20818.20818.4 0.112 7/150 R.HNLITEMVALNPDFKPPADYKPPATR.V "sp|Q15637|SF01_HUMAN,tr|A0A7P0T9U7|A0A7P0T9U7_HUMAN" 2 2934.5062 2.33 148093 20818 4 2934.513666 734.6338 Splicing factor 1 OS=Homo sapiens OX=9606 GN=SF1 PE=1 SV=4 6.75 3573.7 - 65062.3 - - - 2.5446 - 1.4 0.201 - 20.2 1 2 0 0.0075 26 0 0 0 1.58E+06 6.76E+05 - - - 1.0796 0.8146 221125_WJC_METTL3_EV_vs_WT_F10.20821.20821.4 8.17E-06 13/120 R.K[136.11]HAASDVDLEIESLLNQQSTK[136.11].E "sp|Q86U44|MTA70_HUMAN,tr|F5H6D8|F5H6D8_HUMAN,tr|H0YFV6|H0YFV6_HUMAN,tr|B4DTN4|B4DTN4_HUMAN" 4 2341.2096 0.01 148095 20821 4 2342.196113 586.3097 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 4.75 3574.1 - 82595.4 - - - 421.3608 - 2.815 0.435 - 143.7 1 2 0 0.9865 21 0 0 0 1.35E+04 1.72E+06 - - - 3.0812 0.7939 221125_WJC_METTL3_EV_vs_WT_F10.20841.20841.4 0.0953 4/126 K.EK[136.11]K[136.11]DELDSLITAITTNGAHPSK[136.11].C "sp|Q13485|SMAD4_HUMAN,tr|K7EIU8|K7EIU8_HUMAN,tr|K7EL18|K7EL18_HUMAN,tr|K7ENG1|K7ENG1_HUMAN,tr|K7EL15|K7EL15_HUMAN,tr|K7EIJ2|K7EIJ2_HUMAN,tr|K7ES96|K7ES96_HUMAN" 7 2391.2708 1.41 148104 20841 4 2391.272082 598.825 Mothers against decapentaplegic homolog 4 OS=Homo sapiens OX=9606 GN=SMAD4 PE=1 SV=1 5.49 3576.9 - 66011.2 - - - 0.5491 - 1.175 0.199 - 8.4 4 2 1 0.0013 22 0 0 0 3.97E+06 2.82E+06 - - - 0.5516 0.8728 221125_WJC_METTL3_EV_vs_WT_F10.20845.20845.2 0.0563 20-Jun R.TVSESVQR[166.11]NK[136.11]R[166.11].D sp|Q8N103|TAGAP_HUMAN 1 1330.7312 0.001 148105 20845 2 1330.736826 666.3729 T-cell activation Rho GTPase-activating protein OS=Homo sapiens OX=9606 GN=TAGAP PE=1 SV=1 10.83 3577.5 - 427531 - - - 4.2646 - 1.53 0.282 - 162 1 2 1 0.0057 11 0 0 0 0.00E+00 1.30E+07 - - - 2.2725 0.9996 221125_WJC_METTL3_EV_vs_WT_F10.20910.20910.2 0.000442 Jul-34 K.SSGPTSLFAVTVAPPGAR[166.11].Q "sp|Q00839|HNRPU_HUMAN,tr|A0A1W2PP35|A0A1W2PP35_HUMAN,tr|A0A1W2PPS1|A0A1W2PPS1_HUMAN,tr|A0A1W2PP22|A0A1W2PP22_HUMAN,tr|A0A1X7SBS1|A0A1X7SBS1_HUMAN" 5 1723.9133 1.08 148133 20910 2 1723.916018 862.9639 Heterogeneous nuclear ribonucleoprotein U OS=Homo sapiens OX=9606 GN=HNRNPU PE=1 SV=6 9.47 3587.4 - 55239 - - - 1.6033 - 1.671 0.489 - 138.3 1 2 0 0.0028 18 0 0 0 3.02E+06 2.79E+06 - - - 3.9142 0.9998 221125_WJC_METTL3_EV_vs_WT_F10.20914.20914.3 3.83E-06 Dec-68 K.LVINGNPITIFQER[166.11]DPSK[136.11].L sp|P04406|G3P_HUMAN 1 2058.1229 1.08 148135 20914 3 2058.124865 687.0482 Glyceraldehyde-3-phosphate dehydrogenase OS=Homo sapiens OX=9606 GN=GAPDH PE=1 SV=3 6.07 3587.9 - 242450 - - - 0.9742 - 2.591 0.484 - 122.4 1 2 1 0.002 18 0 0 0 9.05E+06 8.42E+06 - - - 6.3063 1 221125_WJC_METTL3_EV_vs_WT_F10.20916.20916.4 2.09E-08 15/138 R.ERPQDRPEDLDVPPALADFIHQQR.T sp|Q01780|EXOSX_HUMAN 1 2841.4158 1.42 148136 20916 4 2841.416807 711.3612 Exosome component 10 OS=Homo sapiens OX=9606 GN=EXOSC10 PE=1 SV=2 4.52 3588.2 - 62080.3 - - - 0.353 - 2.967 0.626 - 130.2 1 2 0 0.001 24 0 0 0 6.97E+06 4.92E+06 - - - 5.0235 1 221125_WJC_METTL3_EV_vs_WT_F10.20919.20919.4 1.27E-07 12/138 R.ER[166.11]PQDR[166.11]PEDLDVPPALADFIHQQR[166.11].T sp|Q01780|EXOSX_HUMAN 1 2871.4406 1.52 148138 20919 4 2871.447932 718.8674 Exosome component 10 OS=Homo sapiens OX=9606 GN=EXOSC10 PE=1 SV=2 4.52 3588.5 - 60445 - - - 2.5485 - 2.56 0.642 - 92.8 1 2 0 0.0073 24 0 0 0 7.50E+06 4.95E+06 - - - 5.1137 0.9984 221125_WJC_METTL3_EV_vs_WT_F10.20924.20924.3 1.31E-07 15/80 C.LAISTPDAPATQDGVESLLQK[136.11].F "sp|Q86U44|MTA70_HUMAN,tr|B4E349|B4E349_HUMAN,tr|F5H6D8|F5H6D8_HUMAN,tr|H0YFV6|H0YFV6_HUMAN,tr|B4DTN4|B4DTN4_HUMAN" 5 2161.1358 0 148141 20924 3 2161.134223 721.3859 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 4.03 3589.2 - 241284 - - - -0.72 - 2.93 0.57 - 263.1 1 1 0 -0.0016 21 0 0 0 3.90E+04 9.51E+06 - - - 7.4718 0.9675 221125_WJC_METTL3_EV_vs_WT_F10.20928.20928.3 0.00231 Aug-52 K.LLHHLSDLALTLPT.D "sp|Q86U44|MTA70_HUMAN,tr|B4E349|B4E349_HUMAN,tr|F5H6D8|F5H6D8_HUMAN,tr|H0YFV6|H0YFV6_HUMAN,tr|B4DTN4|B4DTN4_HUMAN" 5 1542.877 - 148143 20928 3 1542.877491 515.2996 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 5.97 3589.8 - 126962 - - - 0.3318 - 1.994 0.341 - 63.5 1 1 0 0.0005 14 0 0 0 - - - - - 4.1757 0.9998 221125_WJC_METTL3_EV_vs_WT_F10.20932.20932.4 0.000428 8/108 K.NTHATTHNAYDLEVIDIFK[136.11].L "sp|P09874|PARP1_HUMAN,tr|A0A7I2V3E1|A0A7I2V3E1_HUMAN" 2 2209.0895 1.28 148145 20932 4 2209.08746 553.2797 Poly [ADP-ribose] polymerase 1 OS=Homo sapiens OX=9606 GN=PARP1 PE=1 SV=4 5.21 3590.5 - 82679.9 - - - -0.9221 - 1.778 0.384 - 53.1 1 2 0 -0.002 19 0 0 0 1.40E+06 1.09E+06 - - - 2.7624 1 221125_WJC_METTL3_EV_vs_WT_F10.20944.20944.4 0.000522 18/144 K.RSEQDVKPKPVDATDPAALIAEALK.K "sp|Q15390|MTFR1_HUMAN,tr|H0YBZ4|H0YBZ4_HUMAN,tr|H7C5V5|H7C5V5_HUMAN,tr|H0YF01|H0YF01_HUMAN" 4 2661.4337 1.97 148148 20944 4 2661.43927 666.3657 Mitochondrial fission regulator 1 OS=Homo sapiens OX=9606 GN=MTFR1 PE=1 SV=2 4.86 3592.4 - 215908 - - - 2.0759 - 3.428 0.582 - 221.8 1 2 0 0.0055 25 0 0 0 8.52E+06 4.32E+06 - - - 4.6821 0.9983 221125_WJC_METTL3_EV_vs_WT_F10.20974.20974.2 0.0398 22-May K.NIEDVIAQGIGK[136.11].L "sp|P05387|RLA2_HUMAN,tr|H0YDD8|H0YDD8_HUMAN" 2 1263.6914 1.28 148162 20974 2 1263.693295 632.853 60S acidic ribosomal protein P2 OS=Homo sapiens OX=9606 GN=RPLP2 PE=1 SV=1 4.37 3596.9 - 50802.9 - - - 1.4869 - 1.174 0.392 - 48.2 1 2 0 0.0019 12 0 0 0 3.38E+06 2.64E+06 - - - 2.3578 0.9554 221125_WJC_METTL3_EV_vs_WT_F10.21017.21017.3 0.579 Apr-44 K.K[136.11]PGGFDISLFYR[166.11].D "sp|P12956|XRCC6_HUMAN,tr|B1AHC9|B1AHC9_HUMAN" 2 1416.7521 0.21 148176 21017 3 1416.756756 473.258 X-ray repair cross-complementing protein 6 OS=Homo sapiens OX=9606 GN=XRCC6 PE=1 SV=2 8.59 3603.7 - 28604.2 - - - 3.3174 - 1.052 0.283 - 18.6 1 2 0 0.0047 12 0 0 0 3.62E+05 1.73E+06 - - - 1.8344 0.9481 221125_WJC_METTL3_EV_vs_WT_F10.21024.21024.4 0.0619 5/120 R.K[136.11]HAASDVDLEIESLLNQQSTK[136.11].E "sp|Q86U44|MTA70_HUMAN,tr|F5H6D8|F5H6D8_HUMAN,tr|H0YFV6|H0YFV6_HUMAN,tr|B4DTN4|B4DTN4_HUMAN" 4 2341.2096 0.03 148179 21024 4 2342.211763 586.3097 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 4.75 3604.6 - 62740.1 - - - 428.0454 - 1.207 0.308 - 10.1 1 2 0 1.0021 21 0 0 0 1.57E+05 5.58E+06 - - - 1.6914 0.9999 221125_WJC_METTL3_EV_vs_WT_F10.21053.21053.4 1.21E-05 13/198 R.SDSPVPTAPTSGGPK[136.11]PSTASAVPELATDPELEK[136.11]K[136.11].L "sp|Q86U44|MTA70_HUMAN,tr|B4E349|B4E349_HUMAN,tr|F5H6D8|F5H6D8_HUMAN,tr|B4DTN4|B4DTN4_HUMAN" 4 3384.7363 0 148190 21053 4 3384.73834 847.1913 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 4.51 3608.9 - 347327 - - - 0.6142 - 2.879 0.456 - 53.6 1 2 0 0.0021 34 0 0 0 7.64E+04 1.94E+07 - - - 3.5098 1 221125_WJC_METTL3_EV_vs_WT_F10.21098.21098.3 6.09E-07 9/124 R.KINSSPNVNTTASGVEDLNIIQVTIPDDDNER.L "sp|P78347|GTF2I_HUMAN,tr|A0A494C1K3|A0A494C1K3_HUMAN" 2 3467.7016 1.75 148204 21098 3 3467.706986 1156.9078 General transcription factor II-I OS=Homo sapiens OX=9606 GN=GTF2I PE=1 SV=2 3.96 3615.8 - 59732.2 - - - 1.5532 - 1.966 0.669 - 38.1 1 2 0 0.0054 32 0 0 0 2.96E+06 1.69E+06 - - - 7.5524 0.9996 221125_WJC_METTL3_EV_vs_WT_F10.21101.21101.3 1.09E-05 5/124 R.K[136.11]INSSPNVNTTASGVEDLNIIQVTIPDDDNER[166.11].L "sp|P78347|GTF2I_HUMAN,tr|A0A494C1K3|A0A494C1K3_HUMAN" 2 3485.7241 1.75 148205 21101 3 3485.712272 1162.9153 General transcription factor II-I OS=Homo sapiens OX=9606 GN=GTF2I PE=1 SV=2 3.96 3616.3 - 44187.1 - - - -3.3847 - 1.518 0.527 - 11.9 1 2 0 -0.0118 32 0 0 0 2.96E+06 1.69E+06 - - - 5.3725 0.9988 221125_WJC_METTL3_EV_vs_WT_F10.21130.21130.2 0.0179 22-Jun R.VFIGNLNTLVVK.K "sp|P0DMR1|HNRC4_HUMAN,sp|P07910|HNRPC_HUMAN,sp|O60812|HNRC1_HUMAN,sp|B2RXH8|HNRC2_HUMAN,sp|B7ZW38|HNRC3_HUMAN,tr|G3V251|G3V251_HUMAN,tr|B4DY08|B4DY08_HUMAN,tr|G3V575|G3V575_HUMAN,tr|B4DSU6|B4DSU6_HUMAN,tr|G3V3K6|G3V3K6_HUMAN,tr|B2R5W2|B2R5W2_HUMAN,tr|G3V4C1|G3V4C1_HUMAN,tr|A0A0G2JPF8|A0A0G2JPF8_HUMAN,tr|A0A0G2JNQ3|A0A0G2JNQ3_HUMAN,tr|G3V576|G3V576_HUMAN,tr|G3V5X6|G3V5X6_HUMAN,tr|G3V2H6|G3V2H6_HUMAN,tr|G3V4W0|G3V4W0_HUMAN,tr|G3V555|G3V555_HUMAN,tr|G3V4M8|G3V4M8_HUMAN,tr|G3V2Q1|G3V2Q1_HUMAN" 21 1315.7864 1.13 148216 21130 2 1315.787799 658.9005 Heterogeneous nuclear ribonucleoprotein C-like 4 OS=Homo sapiens OX=9606 GN=HNRNPCL4 PE=3 SV=1 8.72 3620.8 - 38547.8 - - - 1.0838 - 1.196 0.405 - 86.6 1 2 0 0.0014 12 0 0 0 4.41E+06 3.92E+06 - - - 2.5028 0.8824 221125_WJC_METTL3_EV_vs_WT_F10.21162.21162.3 0.302 Mar-52 K.SNSFFEGVDWEHIR.E sp|Q15208|STK38_HUMAN 1 1721.7798 52.28 148229 21162 3 1721.774523 574.9339 Serine\threonine-protein kinase 38 OS=Homo sapiens OX=9606 GN=STK38 PE=1 SV=1 4.65 3625.6 - 70576.7 - - - -3.0556 - 0.91 0.252 - 9.8 1 2 0 -0.0053 14 0 0 0 1.51E+06 2.88E+04 - - - 1.0975 0.9958 221125_WJC_METTL3_EV_vs_WT_F10.21167.21167.2 0.000941 22-Jul K.GLTPSQIGVILR.D "sp|P62277|RS13_HUMAN,tr|J3KMX5|J3KMX5_HUMAN" 2 1252.7503 726.19 148231 21167 2 1252.749062 627.3824 40S ribosomal protein S13 OS=Homo sapiens OX=9606 GN=RPS13 PE=1 SV=2 9.75 3626.2 - 41640.3 - - - -1.0058 - 1.538 0.161 - 191.2 1 2 0 -0.0013 12 0 0 0 1.03E+07 1.42E+04 - - - 1.3624 0.9991 221125_WJC_METTL3_EV_vs_WT_F10.21194.21194.2 0.00273 28-May K.GFGFVTFENSADADR.A "sp|O43251|RFOX2_HUMAN,sp|Q9NWB1|RFOX1_HUMAN,tr|A0A6Q8PGE0|A0A6Q8PGE0_HUMAN,tr|A0A6Q8PH77|A0A6Q8PH77_HUMAN,tr|A0A286YEU2|A0A286YEU2_HUMAN,tr|A0A087X2B1|A0A087X2B1_HUMAN,tr|F8VR27|F8VR27_HUMAN,tr|B7Z1U7|B7Z1U7_HUMAN,tr|B0QYV1|B0QYV1_HUMAN,tr|A0A6Q8PHA3|A0A6Q8PHA3_HUMAN,tr|F8VZY7|F8VZY7_HUMAN,tr|B0QYY4|B0QYY4_HUMAN,tr|J3KNW3|J3KNW3_HUMAN,tr|F8VZG9|F8VZG9_HUMAN,tr|F8VRS4|F8VRS4_HUMAN,tr|A0A6Q8PFM4|A0A6Q8PFM4_HUMAN,tr|S4R469|S4R469_HUMAN,tr|A0A804HKG7|A0A804HKG7_HUMAN,tr|A0A0G2JRD1|A0A0G2JRD1_HUMAN,tr|A0A0G2JRA5|A0A0G2JRA5_HUMAN,tr|A0A804HJM2|A0A804HJM2_HUMAN,tr|I3L1D4|I3L1D4_HUMAN,tr|B0QYY7|B0QYY7_HUMAN,tr|A0A0G2JSB3|A0A0G2JSB3_HUMAN,tr|S4R3K7|S4R3K7_HUMAN" 25 1631.7216 1.42 148241 21194 2 1631.718927 816.8681 RNA binding protein fox-1 homolog 2 OS=Homo sapiens OX=9606 GN=RBFOX2 PE=1 SV=3 4.03 3630.2 - 57032.1 - - - -1.6381 - 1.428 0.411 - 68 1 2 0 -0.0027 15 0 0 0 1.21E+06 8.52E+05 - - - 2.9517 0.9895 221125_WJC_METTL3_EV_vs_WT_F10.21197.21197.2 0.0435 28-Apr K.GFGFVTFENSADADR[166.11].A "sp|O43251|RFOX2_HUMAN,sp|Q9NWB1|RFOX1_HUMAN,tr|A0A6Q8PGE0|A0A6Q8PGE0_HUMAN,tr|A0A6Q8PH77|A0A6Q8PH77_HUMAN,tr|A0A286YEU2|A0A286YEU2_HUMAN,tr|A0A087X2B1|A0A087X2B1_HUMAN,tr|F8VR27|F8VR27_HUMAN,tr|B7Z1U7|B7Z1U7_HUMAN,tr|B0QYV1|B0QYV1_HUMAN,tr|A0A6Q8PHA3|A0A6Q8PHA3_HUMAN,tr|F8VZY7|F8VZY7_HUMAN,tr|B0QYY4|B0QYY4_HUMAN,tr|J3KNW3|J3KNW3_HUMAN,tr|F8VZG9|F8VZG9_HUMAN,tr|F8VRS4|F8VRS4_HUMAN,tr|A0A6Q8PFM4|A0A6Q8PFM4_HUMAN,tr|S4R469|S4R469_HUMAN,tr|A0A804HKG7|A0A804HKG7_HUMAN,tr|A0A0G2JRD1|A0A0G2JRD1_HUMAN,tr|A0A0G2JRA5|A0A0G2JRA5_HUMAN,tr|A0A804HJM2|A0A804HJM2_HUMAN,tr|I3L1D4|I3L1D4_HUMAN,tr|B0QYY7|B0QYY7_HUMAN,tr|A0A0G2JSB3|A0A0G2JSB3_HUMAN,tr|S4R3K7|S4R3K7_HUMAN" 25 1641.7299 1.42 148243 21197 2 1641.723983 821.8722 RNA binding protein fox-1 homolog 2 OS=Homo sapiens OX=9606 GN=RBFOX2 PE=1 SV=3 4.03 3630.6 - 37977.9 - - - -3.5859 - 0.869 0.448 - 36.8 1 2 0 -0.0059 15 0 0 0 1.21E+06 8.52E+05 - - - 2.0029 1 221125_WJC_METTL3_EV_vs_WT_F10.21242.21242.4 3.90E-10 25/192 R.AEQDSTTVAAFASSLVSGLNSSASEPAK[136.11]EPAK[136.11]K[136.11].S "sp|Q86U44|MTA70_HUMAN,tr|F5H6D8|F5H6D8_HUMAN,tr|H0YFV6|H0YFV6_HUMAN,tr|B4DTN4|B4DTN4_HUMAN" 4 3301.674 0.05 148254 21242 4 3301.661593 826.4258 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 4.87 3637.6 - 333914 - - - -3.7563 - 4.195 0.683 - 303.9 1 2 1 -0.0124 33 0 0 0 2.03E+06 3.77E+07 - - - 5.5976 1 221125_WJC_METTL3_EV_vs_WT_F10.21280.21280.4 1.70E-07 17/198 R.SDSPVPTAPTSGGPK[136.11]PSTASAVPELATDPELEK[136.11]K[136.11].L "sp|Q86U44|MTA70_HUMAN,tr|B4E349|B4E349_HUMAN,tr|F5H6D8|F5H6D8_HUMAN,tr|B4DTN4|B4DTN4_HUMAN" 4 3384.7363 0 148265 21280 4 3384.737811 847.1913 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 4.51 3643.6 - 221240 - - - 0.4579 - 3.11 0.494 - 105 1 2 0 0.0015 34 0 0 0 1.44E+05 3.56E+07 - - - 3.8637 0.9956 221125_WJC_METTL3_EV_vs_WT_F10.21370.21370.2 0.173 22-Jun K.DAGVIAGLNVLR[166.11].L "sp|P0DMV8|HS71A_HUMAN,sp|P34931|HS71L_HUMAN,sp|P0DMV9|HS71B_HUMAN,tr|Q53FA3|Q53FA3_HUMAN,tr|A0A0G2JIW1|A0A0G2JIW1_HUMAN" 5 1206.696 0.15 148294 21370 2 1206.69679 604.3553 Heat shock 70 kDa protein 1A OS=Homo sapiens OX=9606 GN=HSPA1A PE=1 SV=1 5.84 3657.4 - 29964.4 - - - 0.6621 - 1.243 0.228 - 115.5 1 2 0 0.0008 12 0 0 0 9.22E+05 6.13E+06 - - - 1.2971 0.9983 221125_WJC_METTL3_EV_vs_WT_F10.21372.21372.2 8.60E-05 26-May K.LISWYDNEFGYSNR[166.11].V "sp|P04406|G3P_HUMAN,tr|E7EUT5|E7EUT5_HUMAN" 2 1772.8034 1.06 148296 21372 2 1772.810443 887.409 Glyceraldehyde-3-phosphate dehydrogenase OS=Homo sapiens OX=9606 GN=GAPDH PE=1 SV=3 4.37 3657.7 - 26702.1 - - - 3.9897 - 1.465 0.577 - 69.2 1 2 0 0.0071 14 0 0 0 3.93E+06 3.69E+06 - - - 4.2587 0.9994 221125_WJC_METTL3_EV_vs_WT_F10.21373.21373.2 4.94E-05 26-Aug K.LISWYDNEFGYSNR.V "sp|P04406|G3P_HUMAN,tr|E7EUT5|E7EUT5_HUMAN" 2 1762.7951 1.06 148297 21373 2 1762.800188 882.4048 Glyceraldehyde-3-phosphate dehydrogenase OS=Homo sapiens OX=9606 GN=GAPDH PE=1 SV=3 4.37 3657.8 - 22531.4 - - - 2.8863 - 1.725 0.567 - 176.1 1 2 0 0.0051 14 0 0 0 3.93E+06 3.69E+06 - - - 4.5955 0.9812 221125_WJC_METTL3_EV_vs_WT_F10.21404.21404.4 0.000281 11/162 S.TTVAAFASSLVSGLNSSASEPAK[136.11]EPAK[136.11]K[136.11].S "sp|Q86U44|MTA70_HUMAN,tr|F5H6D8|F5H6D8_HUMAN,tr|H0YFV6|H0YFV6_HUMAN,tr|B4DTN4|B4DTN4_HUMAN" 4 2771.4767 0 148310 21404 4 2771.478147 693.8765 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 8.17 3662.2 - 80427.1 - - - 0.508 - 2.092 0.5 - 56.7 1 1 1 0.0014 28 0 0 0 1.11E+04 4.06E+06 - - - 3.8068 0.8973 221125_WJC_METTL3_EV_vs_WT_F10.21406.21406.3 0.114 Apr-52 K.LISWYDNEFGYSNR.V "sp|P04406|G3P_HUMAN,tr|E7EUT5|E7EUT5_HUMAN" 2 1762.7951 1.22 148311 21406 3 1762.793582 588.6056 Glyceraldehyde-3-phosphate dehydrogenase OS=Homo sapiens OX=9606 GN=GAPDH PE=1 SV=3 4.37 3662.4 - 61504.6 - - - -0.8611 - 0.914 0.191 - 24 1 2 0 -0.0015 14 0 0 0 1.46E+06 1.20E+06 - - - 0.4301 1 221125_WJC_METTL3_EV_vs_WT_F10.21463.21463.4 1.66E-06 17/168 R.R[166.11]AEQDSTTVAAFASSLVSGLNSSASEPAK[136.11].E "sp|Q86U44|MTA70_HUMAN,tr|F5H6D8|F5H6D8_HUMAN,tr|H0YFV6|H0YFV6_HUMAN,tr|B4DTN4|B4DTN4_HUMAN" 4 2898.4326 0.001 148326 21463 4 2898.427642 725.6154 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 4.68 3671.4 - 200297 - - - -1.7037 - 3.082 0.579 - 132.6 1 2 0 -0.0049 29 0 0 0 0.00E+00 4.49E+06 - - - 4.6111 1 221125_WJC_METTL3_EV_vs_WT_F10.21485.21485.4 2.62E-07 15/198 R.SDSPVPTAPTSGGPK[136.11]PSTASAVPELATDPELEK[136.11]K[136.11].L "sp|Q86U44|MTA70_HUMAN,tr|B4E349|B4E349_HUMAN,tr|F5H6D8|F5H6D8_HUMAN,tr|B4DTN4|B4DTN4_HUMAN" 4 3384.7363 0 148337 21485 4 3384.739836 847.1913 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 4.51 3674.3 - 242869 - - - 1.0562 - 2.928 0.533 - 90.9 1 2 0 0.0036 34 0 0 0 4.02E+04 1.72E+07 - - - 4.1846 0.9997 221125_WJC_METTL3_EV_vs_WT_F10.21492.21492.3 0.000966 Jul-60 K.K[136.11]VSQEILELLNTTTAK[136.11].E "sp|Q86U44|MTA70_HUMAN,tr|H0YFV6|H0YFV6_HUMAN" 2 1803.0324 0.01 148341 21492 3 1803.025989 602.0181 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 6.14 3675.2 - 60934.4 - - - -3.5723 - 1.616 0.539 - 70.8 1 2 0 -0.0064 16 0 0 0 2.90E+06 4.21E+08 - - - 5.779 0.9808 221125_WJC_METTL3_EV_vs_WT_F10.21515.21515.3 0.0536 Mar-76 K.FEAHPNDLYVEGLPENIPFR.S "sp|P78347|GTF2I_HUMAN,tr|A0A494C0Q7|A0A494C0Q7_HUMAN,tr|A0A494C1K3|A0A494C1K3_HUMAN" 3 2356.1488 2.25 148349 21515 3 2356.154851 786.3902 General transcription factor II-I OS=Homo sapiens OX=9606 GN=GTF2I PE=1 SV=2 4.4 3678.4 - 51852.3 - - - 2.5694 - 1.208 0.33 - 4.5 24 2 0 0.0061 20 0 0 0 1.64E+06 7.32E+05 - - - 2.0371 0.9999 221125_WJC_METTL3_EV_vs_WT_F10.21539.21539.3 0.00173 Oct-60 K.KVSQEILELLNTTTAK[136.11].E "sp|Q86U44|MTA70_HUMAN,tr|H0YFV6|H0YFV6_HUMAN" 2 1795.0182 - 148356 21539 3 1795.017126 599.3467 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 6.14 3682.1 - 120504 - - - -0.615 - 1.996 0.439 - 129.6 1 2 0 -0.0011 16 0 0 0 - - - - - 5.2075 0.9976 221125_WJC_METTL3_EV_vs_WT_F10.21555.21555.2 0.0651 24-Apr K.C[160.03]EFQDAYVLLSEK.K "sp|P10809|CH60_HUMAN,tr|A0A7I2V2X6|A0A7I2V2X6_HUMAN,tr|A0A7I2YQK6|A0A7I2YQK6_HUMAN,tr|A0A7I2V599|A0A7I2V599_HUMAN,tr|A0A7I2YQ71|A0A7I2YQ71_HUMAN,tr|A0A7I2V5M1|A0A7I2V5M1_HUMAN,tr|A0A7I2V5K3|A0A7I2V5K3_HUMAN,tr|A0A7I2V369|A0A7I2V369_HUMAN" 8 1600.7443 1.79 148359 21555 2 1600.741499 801.3794 "60 kDa heat shock protein, mitochondrial OS=Homo sapiens OX=9606 GN=HSPD1 PE=1 SV=2" 4.14 3684.7 - 47708.3 - - - -1.7561 - 0.909 0.453 - 45.8 1 2 0 -0.0028 13 0 0 0 1.84E+06 1.03E+06 - - - 2.1411 0.9833 221125_WJC_METTL3_EV_vs_WT_F10.21557.21557.4 2.83E-09 20/168 D.STTVAAFASSLVSGLNSSASEPAK[136.11]EPAK[136.11]K[136.11].S "sp|Q86U44|MTA70_HUMAN,tr|F5H6D8|F5H6D8_HUMAN,tr|H0YFV6|H0YFV6_HUMAN,tr|B4DTN4|B4DTN4_HUMAN" 4 2858.5088 0.01 148360 21557 4 2858.502205 715.6345 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 8.22 3684.9 - 453099 - - - -2.296 - 3.722 0.554 - 177.6 1 1 1 -0.0066 29 0 0 0 3.34E+05 2.87E+07 - - - 4.4512 1 221125_WJC_METTL3_EV_vs_WT_F10.21559.21559.4 1.25E-12 35/192 R.R[166.11]AEQDSTTVAAFASSLVSGLNSSASEPAK[136.11]EPAK[136.11].K "sp|Q86U44|MTA70_HUMAN,tr|F5H6D8|F5H6D8_HUMAN,tr|H0YFV6|H0YFV6_HUMAN,tr|B4DTN4|B4DTN4_HUMAN" 4 3331.6742 0.49 148361 21559 4 3332.656424 833.9258 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 4.87 3685.1 - 634484 - - - 294.81 - 5.452 0.683 - 912.4 1 2 1 0.9822 33 0 0 0 7.56E+06 1.55E+07 - - - 5.4076 0.9991 221125_WJC_METTL3_EV_vs_WT_F10.21573.21573.2 0.00264 18-May K.NGFLLDGFPR[166.11].T "sp|P54819|KAD2_HUMAN,tr|A0A5F9ZHP2|A0A5F9ZHP2_HUMAN,tr|G3V213|G3V213_HUMAN,tr|F8VY04|F8VY04_HUMAN,tr|F8W1A4|F8W1A4_HUMAN,tr|A0A5K1VW67|A0A5K1VW67_HUMAN,tr|F8VZG5|F8VZG5_HUMAN" 7 1144.5905 0.41 148367 21573 2 1144.589565 573.3025 "Adenylate kinase 2, mitochondrial OS=Homo sapiens OX=9606 GN=AK2 PE=1 SV=2" 5.84 3687.1 - 82229.3 - - - -0.7854 - 1.234 0.4 - 75.3 1 2 0 -0.0009 10 0 0 0 3.14E+06 7.61E+06 - - - 2.582 1 221125_WJC_METTL3_EV_vs_WT_F10.21691.21691.4 8.57E-07 12/198 R.SDSPVPTAPTSGGPK[136.11]PSTASAVPELATDPELEK[136.11]K[136.11].L "sp|Q86U44|MTA70_HUMAN,tr|B4E349|B4E349_HUMAN,tr|F5H6D8|F5H6D8_HUMAN,tr|B4DTN4|B4DTN4_HUMAN" 4 3384.7363 0 148398 21691 4 3384.739737 847.1913 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 4.51 3705.6 - 230364 - - - 1.027 - 2.557 0.488 - 46.5 1 2 0 0.0035 34 0 0 0 6.69E+04 3.56E+07 - - - 3.7526 1 221125_WJC_METTL3_EV_vs_WT_F10.21692.21692.3 1.88E-06 Aug-60 K.K[136.11]VSQEILELLNTTTAK[136.11].E "sp|Q86U44|MTA70_HUMAN,tr|H0YFV6|H0YFV6_HUMAN" 2 1803.0324 0.02 148399 21692 3 1803.032467 602.0181 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 6.14 3705.7 - 135289 - - - 0.0205 - 1.96 0.562 - 77.6 1 2 0 0 16 0 0 0 1.24E+05 7.26E+06 - - - 6.5324 0.9944 221125_WJC_METTL3_EV_vs_WT_F10.21714.21714.2 0.00488 26-Apr R.GFAFVTFESPADAK.A "sp|O75526|RMXL2_HUMAN,sp|Q96E39|RMXL1_HUMAN,sp|Q8N7X1|RMXL3_HUMAN,sp|P38159|RBMX_HUMAN,tr|A0A1B0GUK8|A0A1B0GUK8_HUMAN,tr|H3BT71|H3BT71_HUMAN,tr|H0Y6E7|H0Y6E7_HUMAN,tr|H3BR27|H3BR27_HUMAN" 8 1485.714 1.15 148408 21714 2 1485.717493 743.8643 "RNA-binding motif protein, X-linked-like-2 OS=Homo sapiens OX=9606 GN=RBMXL2 PE=1 SV=3" 4.37 3709 - 17165.2 - - - 2.3538 - 0.883 0.42 - 33.5 1 2 0 0.0035 14 0 0 0 5.77E+05 5.03E+05 - - - 1.8298 1 221125_WJC_METTL3_EV_vs_WT_F10.21757.21757.4 8.02E-16 29/192 R.AEQDSTTVAAFASSLVSGLNSSASEPAK[136.11]EPAK[136.11]K[136.11].S "sp|Q86U44|MTA70_HUMAN,tr|F5H6D8|F5H6D8_HUMAN,tr|H0YFV6|H0YFV6_HUMAN,tr|B4DTN4|B4DTN4_HUMAN" 4 3301.674 0.19 148421 21757 4 3302.670236 826.4258 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 4.87 3715.7 - 309606 - - - 301.7381 - 4.423 0.725 - 541.7 1 2 1 0.9962 33 0 0 0 4.36E+06 2.32E+07 - - - 5.7065 1 221125_WJC_METTL3_EV_vs_WT_F10.21803.21803.3 2.84E-07 19/76 K.HAASDVDLEIESLLNQQSTK[136.11].E "sp|Q86U44|MTA70_HUMAN,tr|F5H6D8|F5H6D8_HUMAN,tr|H0YFV6|H0YFV6_HUMAN,tr|B4DTN4|B4DTN4_HUMAN" 4 2205.1005 0.02 148432 21803 3 2206.091234 736.0408 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 4.31 3722.9 - 762609 - - - 449.312 - 3.961 0.665 - 441.2 1 2 0 0.9908 20 0 0 0 6.21E+06 2.53E+08 - - - 9.0191 0.9998 221125_WJC_METTL3_EV_vs_WT_F10.21855.21855.4 5.39E-05 8/114 K.HAASDVDLEIESLLNQQSTK[136.11].E "sp|Q86U44|MTA70_HUMAN,tr|F5H6D8|F5H6D8_HUMAN,tr|H0YFV6|H0YFV6_HUMAN,tr|B4DTN4|B4DTN4_HUMAN" 4 2205.1005 0.23 148447 21855 4 2205.092097 552.2824 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 4.31 3730.6 - 103021 - - - -3.7908 - 1.988 0.512 - 39.3 1 2 0 -0.0084 20 0 0 0 1.88E+06 8.19E+06 - - - 3.9099 0.9999 221125_WJC_METTL3_EV_vs_WT_F10.21860.21860.3 3.12E-07 9/120 R.SSSTGSSSSTGGGGQESQPSPLALLAATC[160.03]SR[166.11].L "sp|P08047|SP1_HUMAN,tr|H3BVI2|H3BVI2_HUMAN" 2 2934.35 1.28 148450 21860 3 2934.34145 979.124 Transcription factor Sp1 OS=Homo sapiens OX=9606 GN=SP1 PE=1 SV=3 5.72 3731.2 - 73012.6 - - - -2.9281 - 2.059 0.643 - 63.2 1 2 0 -0.0086 31 0 0 0 3.37E+06 2.64E+06 - - - 7.368 1 221125_WJC_METTL3_EV_vs_WT_F10.21926.21926.4 8.28E-07 10/198 R.SDSPVPTAPTSGGPK[136.11]PSTASAVPELATDPELEK[136.11]K[136.11].L "sp|Q86U44|MTA70_HUMAN,tr|B4E349|B4E349_HUMAN,tr|F5H6D8|F5H6D8_HUMAN,tr|B4DTN4|B4DTN4_HUMAN" 4 3384.7363 0.01 148475 21926 4 3384.738536 847.1913 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 4.51 3741.4 - 224879 - - - 0.6721 - 2.452 0.495 - 36 1 2 0 0.0023 34 0 0 0 3.25E+05 2.18E+07 - - - 3.8013 0.9982 221125_WJC_METTL3_EV_vs_WT_F10.21938.21938.2 0.0888 18-May K.ILLAELEQLK.G "sp|P08670|VIME_HUMAN,tr|B0YJC4|B0YJC4_HUMAN,tr|A0A1B0GTT5|A0A1B0GTT5_HUMAN" 3 1168.7067 2.08 148482 21938 2 1168.706304 585.3606 Vimentin OS=Homo sapiens OX=9606 GN=VIM PE=1 SV=4 4.53 3743 - 95022.2 - - - -0.3602 - 1.278 0.291 - 58 1 2 0 -0.0004 10 0 0 0 2.48E+06 1.19E+06 - - - 1.8749 1 221125_WJC_METTL3_EV_vs_WT_F10.21977.21977.3 1.02E-14 21/128 R.R[166.11]AEQDSTTVAAFASSLVSGLNSSASEPAK[136.11]EPAK[136.11].K "sp|Q86U44|MTA70_HUMAN,tr|F5H6D8|F5H6D8_HUMAN,tr|H0YFV6|H0YFV6_HUMAN,tr|B4DTN4|B4DTN4_HUMAN" 4 3331.6742 0.05 148497 21977 3 3332.668539 1111.5653 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 4.87 3748.7 - 508101 - - - 298.4463 - 4.603 0.713 - 381.9 1 2 1 0.9943 33 0 0 0 7.43E+06 1.39E+08 - - - 9.7262 0.9996 221125_WJC_METTL3_EV_vs_WT_F10.21989.21989.4 7.76E-11 27/174 K.R[166.11]R[166.11]AEQDSTTVAAFASSLVSGLNSSASEPAK[136.11].E "sp|Q86U44|MTA70_HUMAN,tr|F5H6D8|F5H6D8_HUMAN,tr|H0YFV6|H0YFV6_HUMAN,tr|B4DTN4|B4DTN4_HUMAN" 4 3064.542 0.02 148500 21989 4 3064.528869 767.1428 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 6.18 3750.5 - 936582 - - - -4.2721 - 4.05 0.604 - 427.1 1 2 1 -0.0131 30 0 0 0 2.51E+06 1.24E+08 - - - 4.9076 1 221125_WJC_METTL3_EV_vs_WT_F10.22002.22002.2 2.83E-07 17/30 V.SGLNSSASEPAK[136.11]EPAK[136.11].K "sp|Q86U44|MTA70_HUMAN,tr|F5H6D8|F5H6D8_HUMAN,tr|H0YFV6|H0YFV6_HUMAN,tr|B4DTN4|B4DTN4_HUMAN" 4 1587.8075 0.01 148502 22002 2 1588.798885 794.911 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 5.86 3752.5 - 2.04E+06 - - - 624.3641 - 2.976 0.599 - 813 1 1 1 0.9914 16 0 0 0 1.31E+05 2.46E+07 - - - 5.8352 1 221125_WJC_METTL3_EV_vs_WT_F10.22022.22022.2 3.69E-16 27/64 R.R[166.11]AEQDSTTVAAFASSLVSGLNSSASEPAK[136.11]EPAK[136.11].K "sp|Q86U44|MTA70_HUMAN,tr|F5H6D8|F5H6D8_HUMAN,tr|H0YFV6|H0YFV6_HUMAN,tr|B4DTN4|B4DTN4_HUMAN" 4 3331.6742 -1 148503 22022 2 3332.655895 1666.8444 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 4.87 3755.8 - 1.58E+06 - - - 294.6513 - 4.753 0.72 - 320.8 1 2 1 0.9817 33 0 0 0 0.00E+00 0.00E+00 - - - 7.883 1 221125_WJC_METTL3_EV_vs_WT_F10.22029.22029.2 6.85E-15 20/30 V.SGLNSSASEPAK[136.11]EPAK[136.11].K "sp|Q86U44|MTA70_HUMAN,tr|F5H6D8|F5H6D8_HUMAN,tr|H0YFV6|H0YFV6_HUMAN,tr|B4DTN4|B4DTN4_HUMAN" 4 1587.8075 0.01 148505 22029 2 1587.797073 794.911 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 5.86 3756.9 - 3.49E+06 - - - -6.5764 - 3.723 0.668 - 1296.9 1 1 1 -0.0104 16 0 0 0 1.31E+05 2.46E+07 - - - 7.2034 1 221125_WJC_METTL3_EV_vs_WT_F10.22040.22040.2 6.75E-12 17/28 S.GLNSSASEPAK[136.11]EPAK[136.11].K "sp|Q86U44|MTA70_HUMAN,tr|F5H6D8|F5H6D8_HUMAN,tr|H0YFV6|H0YFV6_HUMAN,tr|B4DTN4|B4DTN4_HUMAN" 4 1500.7755 0.02 148506 22040 2 1500.769544 751.395 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 6.14 3758.6 - 680063 - - - -3.96 - 3.071 0.638 - 1002.6 1 1 1 -0.0059 15 0 0 0 5.22E+05 2.63E+07 - - - 6.5099 0.998 221125_WJC_METTL3_EV_vs_WT_F10.22085.22085.3 0.00226 Aug-56 R.DYLHLPPEIVPATLR[166.11].R "sp|P46783|RS10_HUMAN,tr|A0A2R8Y6L3|A0A2R8Y6L3_HUMAN,tr|F6U211|F6U211_HUMAN,tr|A0A1W2PQS6|A0A1W2PQS6_HUMAN,tr|A0A2R8YFH6|A0A2R8YFH6_HUMAN,tr|A0A2R8Y7H1|A0A2R8Y7H1_HUMAN,tr|S4R435|S4R435_HUMAN" 7 1742.9595 1.71 148513 22085 3 1742.95262 581.9938 40S ribosomal protein S10 OS=Homo sapiens OX=9606 GN=RPS10 PE=1 SV=1 5.32 3765.8 - 115343 - - - -3.9335 - 1.615 0.407 - 65.1 1 2 0 -0.0069 15 0 0 0 4.08E+06 2.39E+06 - - - 4.3265 0.999 221125_WJC_METTL3_EV_vs_WT_F10.22097.22097.3 3.41E-08 14/116 K.R[166.11]R[166.11]AEQDSTTVAAFASSLVSGLNSSASEPAK[136.11].E "sp|Q86U44|MTA70_HUMAN,tr|F5H6D8|F5H6D8_HUMAN,tr|H0YFV6|H0YFV6_HUMAN,tr|B4DTN4|B4DTN4_HUMAN" 4 3064.542 0.001 148517 22097 3 3064.526702 1022.5213 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 6.18 3767.4 - 215980 - - - -4.9792 - 2.772 0.616 - 78.9 1 2 1 -0.0153 30 0 0 0 0.00E+00 5.41E+06 - - - 7.7492 0.9872 221125_WJC_METTL3_EV_vs_WT_F10.22102.22102.2 0.00577 22-Apr R.LFPPQWIC[160.03]C[160.03]DIR[166.11].Y sp|Q86U44|MTA70_HUMAN 1 1613.7722 0.001 148519 22102 2 1613.767413 807.8934 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 5.82 3768 - 146874 - - - -2.9725 - 1.028 0.322 - 42.6 1 2 0 -0.0048 12 0 0 0 0.00E+00 1.12E+07 - - - 1.4904 0.9689 221125_WJC_METTL3_EV_vs_WT_F10.22108.22108.3 0.0154 Jul-56 R.DYLHLPPEIVPATLR.R "sp|P46783|RS10_HUMAN,tr|A0A2R8Y6L3|A0A2R8Y6L3_HUMAN,tr|F6U211|F6U211_HUMAN,tr|A0A1W2PQS6|A0A1W2PQS6_HUMAN,tr|A0A2R8YFH6|A0A2R8YFH6_HUMAN,tr|A0A2R8Y7H1|A0A2R8Y7H1_HUMAN,tr|S4R435|S4R435_HUMAN" 7 1732.9512 1.7 148521 22108 3 1732.942754 578.6577 40S ribosomal protein S10 OS=Homo sapiens OX=9606 GN=RPS10 PE=1 SV=1 5.32 3768.8 - 84812.2 - - - -4.8772 - 1.501 0.285 - 43.5 1 2 0 -0.0085 15 0 0 0 4.28E+06 2.51E+06 - - - 2.7749 0.9998 221125_WJC_METTL3_EV_vs_WT_F10.22111.22111.4 6.86E-07 14/114 K.R[166.11]GLLQDDAHPTLVTYADHSK[136.11].L "sp|Q86U44|MTA70_HUMAN,tr|F5H6D8|F5H6D8_HUMAN,tr|H0YFV6|H0YFV6_HUMAN,tr|B4DTN4|B4DTN4_HUMAN" 4 2254.1461 0 148522 22111 4 2254.137965 564.5438 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 5.99 3769.2 - 474453 - - - -3.6156 - 2.517 0.486 - 130.3 1 2 0 -0.0081 20 0 0 0 9.33E+04 4.60E+07 - - - 3.7625 0.9926 221125_WJC_METTL3_EV_vs_WT_F10.22139.22139.3 0.022 May-68 R.IGPYQPNVPVGIDYVIPK.T "sp|P43243|MATR3_HUMAN,tr|B3KM87|B3KM87_HUMAN,tr|A8MXP9|A8MXP9_HUMAN,tr|A0A0R4J2E8|A0A0R4J2E8_HUMAN" 4 1968.072 1.53 148526 22139 3 1968.066645 657.0313 Matrin-3 OS=Homo sapiens OX=9606 GN=MATR3 PE=1 SV=2 5.83 3773.9 - 67392.4 - - - -2.7463 - 1.319 0.312 - 28.8 1 2 0 -0.0054 18 0 0 0 3.45E+06 2.26E+06 - - - 2.7064 0.9587 221125_WJC_METTL3_EV_vs_WT_F10.22144.22144.3 0.576 Apr-68 R.IGPYQPNVPVGIDYVIPK[136.11].T "sp|P43243|MATR3_HUMAN,tr|B3KM87|B3KM87_HUMAN,tr|A8MXP9|A8MXP9_HUMAN,tr|A0A0R4J2E8|A0A0R4J2E8_HUMAN" 4 1976.0863 1.63 148528 22144 3 1976.080352 659.7027 Matrin-3 OS=Homo sapiens OX=9606 GN=MATR3 PE=1 SV=2 5.83 3774.5 - 77707.6 - - - -2.9847 - 1.101 0.264 - 15.7 1 2 0 -0.0059 18 0 0 0 3.45E+06 2.12E+06 - - - 1.7213 0.9378 221125_WJC_METTL3_EV_vs_WT_F10.22148.22148.2 0.59 Mar-34 R.IGPYQPNVPVGIDYVIPK.T "sp|P43243|MATR3_HUMAN,tr|B3KM87|B3KM87_HUMAN,tr|A8MXP9|A8MXP9_HUMAN,tr|A0A0R4J2E8|A0A0R4J2E8_HUMAN" 4 1968.072 1.9 148530 22148 2 1968.069869 985.0433 Matrin-3 OS=Homo sapiens OX=9606 GN=MATR3 PE=1 SV=2 5.83 3774.9 - 68898.9 - - - -1.1082 - 0.771 0.157 - 14.5 1 2 0 -0.0022 18 0 0 0 1.72E+06 9.08E+05 - - - -0.4395 0.9771 221125_WJC_METTL3_EV_vs_WT_F10.22158.22158.3 1.14 Jun-76 K.R[166.11]GLLQDDAHPTLVTYADHSK[136.11].L "sp|Q86U44|MTA70_HUMAN,tr|F5H6D8|F5H6D8_HUMAN,tr|H0YFV6|H0YFV6_HUMAN,tr|B4DTN4|B4DTN4_HUMAN" 4 2254.1461 0.001 148533 22158 3 2254.143309 752.3893 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 5.99 3776.3 - 70639.9 - - - -1.2448 - 1.24 0.208 - 33 1 2 0 -0.0028 20 0 0 0 0.00E+00 4.01E+06 - - - 1.3801 0.9999 221125_WJC_METTL3_EV_vs_WT_F10.22166.22166.3 2.49E-07 13/56 R.STSHK[136.11]PDEIYGMIER[166.11].L sp|Q86U44|MTA70_HUMAN 1 1779.8581 0.01 148537 22166 3 1779.852337 594.2933 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 5.42 3777.4 - 337931 - - - -3.2121 - 2.411 0.525 - 226.8 1 2 0 -0.0057 15 0 0 0 9.21E+04 6.73E+06 - - - 6.688 0.9996 221125_WJC_METTL3_EV_vs_WT_F10.22172.22172.4 0.00191 16/84 R.STSHK[136.11]PDEIYGMIER[166.11].L sp|Q86U44|MTA70_HUMAN 1 1779.8581 0.001 148541 22172 4 1779.850134 445.9718 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 5.42 3778.2 - 297265 - - - -4.4498 - 2.432 0.486 - 190.8 1 2 0 -0.0079 15 0 0 0 0.00E+00 5.01E+06 - - - 3.7719 0.9994 221125_WJC_METTL3_EV_vs_WT_F10.22193.22193.4 0.027 11/198 R.SDSPVPTAPTSGGPK[136.11]PSTASAVPELATDPELEK[136.11]K[136.11].L "sp|Q86U44|MTA70_HUMAN,tr|B4E349|B4E349_HUMAN,tr|F5H6D8|F5H6D8_HUMAN,tr|B4DTN4|B4DTN4_HUMAN" 4 3384.7363 0.03 148551 22193 4 3384.727462 847.1913 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 4.51 3781.1 - 505078 - - - -2.5996 - 2.273 0.368 - 38.1 1 2 0 -0.0088 34 0 0 0 4.13E+05 1.25E+07 - - - 2.6715 0.9994 221125_WJC_METTL3_EV_vs_WT_F10.22202.22202.4 7.62E-07 21/174 K.R[166.11]R[166.11]AEQDSTTVAAFASSLVSGLNSSASEPAK[136.11].E "sp|Q86U44|MTA70_HUMAN,tr|F5H6D8|F5H6D8_HUMAN,tr|H0YFV6|H0YFV6_HUMAN,tr|B4DTN4|B4DTN4_HUMAN" 4 3064.542 0 148553 22202 4 3064.530756 767.1428 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 6.18 3782.5 - 509735 - - - -3.6563 - 3.12 0.513 - 181.6 1 2 1 -0.0112 30 0 0 0 1.30E+05 6.82E+07 - - - 4.0362 1 221125_WJC_METTL3_EV_vs_WT_F10.22213.22213.3 1.33E-17 43/128 R.R[166.11]AEQDSTTVAAFASSLVSGLNSSASEPAK[136.11]EPAK[136.11].K "sp|Q86U44|MTA70_HUMAN,tr|F5H6D8|F5H6D8_HUMAN,tr|H0YFV6|H0YFV6_HUMAN,tr|B4DTN4|B4DTN4_HUMAN" 4 3331.6742 0.07 148555 22213 3 3331.659664 1111.5653 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 4.87 3784.2 - 301537 - - - -4.3669 - 7.085 0.767 - 1965.7 1 2 1 -0.0145 33 0 0 0 9.22E+06 1.39E+08 - - - 11.5919 0.9583 221125_WJC_METTL3_EV_vs_WT_F10.22219.22219.4 0.00135 9/186 A.EQDSTTVAAFASSLVSGLNSSASEPAK[136.11]EPAK[136.11]K[136.11].S "sp|Q86U44|MTA70_HUMAN,tr|F5H6D8|F5H6D8_HUMAN,tr|H0YFV6|H0YFV6_HUMAN,tr|B4DTN4|B4DTN4_HUMAN" 4 3230.6369 0.04 148556 22219 4 3230.627763 808.6665 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 4.87 3785.1 - 200356 - - - -2.8227 - 1.537 0.526 - 21.8 1 1 1 -0.0091 32 0 0 0 4.24E+06 1.15E+08 - - - 3.9316 1 221125_WJC_METTL3_EV_vs_WT_F10.22220.22220.2 2.06E-10 14/32 V.SGLNSSASEPAK[136.11]EPAK[136.11]K[136.11].S "sp|Q86U44|MTA70_HUMAN,tr|F5H6D8|F5H6D8_HUMAN,tr|H0YFV6|H0YFV6_HUMAN,tr|B4DTN4|B4DTN4_HUMAN" 4 1723.9167 0.04 148557 22220 2 1723.902396 862.9656 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 8.22 3785.2 - 0 - - - -8.2846 - 2.887 0.579 - 505 1 1 1 -0.0143 17 0 0 0 8.01E+05 1.94E+07 - - - 5.9196 1 221125_WJC_METTL3_EV_vs_WT_F10.22262.22262.2 5.78E-17 25/64 R.AEQDSTTVAAFASSLVSGLNSSASEPAK[136.11]EPAK[136.11]K[136.11].S "sp|Q86U44|MTA70_HUMAN,tr|F5H6D8|F5H6D8_HUMAN,tr|H0YFV6|H0YFV6_HUMAN,tr|B4DTN4|B4DTN4_HUMAN" 4 3301.674 -1 148560 22262 2 3303.665447 1651.8443 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 4.87 3792.1 - 3.57E+06 - - - 603.1643 - 4.303 0.742 - 474.7 1 2 1 1.9915 33 0 0 0 0.00E+00 0.00E+00 - - - 7.4839 1 221125_WJC_METTL3_EV_vs_WT_F10.22267.22267.4 1.53E-17 26/192 R.R[166.11]AEQDSTTVAAFASSLVSGLNSSASEPAK[136.11]EPAK[136.11].K "sp|Q86U44|MTA70_HUMAN,tr|F5H6D8|F5H6D8_HUMAN,tr|H0YFV6|H0YFV6_HUMAN,tr|B4DTN4|B4DTN4_HUMAN" 4 3331.6742 92.59 148562 22267 4 3331.643515 833.9258 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 4.87 3792.7 - 5.25E+06 - - - -9.214 - 4.986 0.707 - 394.2 1 2 1 -0.0307 33 0 0 0 3.55E+10 3.84E+08 - - - 5.8533 0.8562 221125_WJC_METTL3_EV_vs_WT_F10.22304.22304.3 2.45E-09 21/84 F.ASSLVSGLNSSASEPAK[136.11]EPAK[136.11]K[136.11].S "sp|Q86U44|MTA70_HUMAN,tr|F5H6D8|F5H6D8_HUMAN,tr|H0YFV6|H0YFV6_HUMAN,tr|B4DTN4|B4DTN4_HUMAN" 4 2181.1703 0.001 148565 22304 3 2181.160529 728.0641 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 8.54 3798.8 - 328662 - - - -4.4921 - 3.607 0.438 - 448.2 1 1 1 -0.0098 22 0 0 0 0.00E+00 1.03E+07 - - - 6.462 0.9999 221125_WJC_METTL3_EV_vs_WT_F10.22309.22309.4 1.96E-07 23/114 K.R[166.11]GLLQDDAHPTLVTYADHSK[136.11].L "sp|Q86U44|MTA70_HUMAN,tr|F5H6D8|F5H6D8_HUMAN,tr|H0YFV6|H0YFV6_HUMAN,tr|B4DTN4|B4DTN4_HUMAN" 4 2254.1461 0.001 148566 22309 4 2254.136435 564.5438 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 5.99 3799.5 - 1.89E+06 - - - -4.2943 - 4.038 0.572 - 559.8 1 2 0 -0.0097 20 0 0 0 0.00E+00 7.47E+07 - - - 4.6686 0.9826 221125_WJC_METTL3_EV_vs_WT_F10.22312.22312.3 1.47E-09 15/64 V.SGLNSSASEPAK[136.11]EPAK[136.11]K[136.11].S "sp|Q86U44|MTA70_HUMAN,tr|F5H6D8|F5H6D8_HUMAN,tr|H0YFV6|H0YFV6_HUMAN,tr|B4DTN4|B4DTN4_HUMAN" 4 1723.9167 0.001 148567 22312 3 1723.911594 575.6462 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 8.22 3799.9 - 0 - - - -2.9491 - 3.092 0.617 - 277.9 1 1 1 -0.0051 17 0 0 0 0.00E+00 1.06E+07 - - - 8.2693 0.9985 221125_WJC_METTL3_EV_vs_WT_F10.22339.22339.4 0.00468 5/126 K.TKPIVKPQTSPEYGQGINPISR.L sp|O95793|STAU1_HUMAN 1 2409.3016 5.01 148570 22339 4 2409.292505 603.3327 Double-stranded RNA-binding protein Staufen homolog 1 OS=Homo sapiens OX=9606 GN=STAU1 PE=1 SV=2 9.7 3804.3 - 179360 - - - -3.7787 - 1.076 0.391 - 15.4 1 2 0 -0.0091 22 0 0 0 2.76E+06 5.50E+05 - - - 2.6507 0.9829 221125_WJC_METTL3_EV_vs_WT_F10.22366.22366.2 0.771 22-Feb R.LFPPQWIC[160.03]C[160.03]DIR[166.11].Y sp|Q86U44|MTA70_HUMAN 1 1613.7722 0.001 148581 22366 2 1613.772835 807.8934 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 5.82 3808.1 - 477899 - - - 0.3873 - 0.733 0.323 - 13.2 5 2 0 0.0006 12 0 0 0 0.00E+00 1.63E+06 - - - 0.297 0.9998 221125_WJC_METTL3_EV_vs_WT_F10.22376.22376.3 0.000188 Sep-56 K.VSQEILELLNTTTAK[136.11].E "sp|Q86U44|MTA70_HUMAN,tr|H0YFV6|H0YFV6_HUMAN" 2 1666.9233 0.02 148585 22376 3 1666.92055 556.6484 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 4.53 3809.5 - 565031 - - - -1.6299 - 2.011 0.417 - 125.4 1 2 0 -0.0027 15 0 0 0 1.39E+06 6.38E+07 - - - 5.0114 0.9997 221125_WJC_METTL3_EV_vs_WT_F10.22397.22397.4 3.73E-06 12/198 R.SDSPVPTAPTSGGPK[136.11]PSTASAVPELATDPELEK[136.11]K[136.11].L "sp|Q86U44|MTA70_HUMAN,tr|B4E349|B4E349_HUMAN,tr|F5H6D8|F5H6D8_HUMAN,tr|B4DTN4|B4DTN4_HUMAN" 4 3384.7363 0.01 148591 22397 4 3384.723781 847.1913 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 4.51 3812.8 - 236054 - - - -3.6871 - 2.716 0.454 - 56.7 1 2 0 -0.0125 34 0 0 0 1.15E+05 2.26E+07 - - - 3.4721 0.8528 221125_WJC_METTL3_EV_vs_WT_F10.22456.22456.4 0.000611 7/174 Q.DSTTVAAFASSLVSGLNSSASEPAK[136.11]EPAK[136.11]K[136.11].S "sp|Q86U44|MTA70_HUMAN,tr|F5H6D8|F5H6D8_HUMAN,tr|H0YFV6|H0YFV6_HUMAN,tr|B4DTN4|B4DTN4_HUMAN" 4 2973.5357 0.01 148609 22456 4 2973.537308 744.3912 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 6.18 3821.8 - 103343 - - - 0.5371 - 1.504 0.363 - 20.5 1 1 1 0.0016 30 0 0 0 6.48E+04 4.39E+06 - - - 2.51 1 221125_WJC_METTL3_EV_vs_WT_F10.22461.22461.3 9.55E-14 23/128 R.AEQDSTTVAAFASSLVSGLNSSASEPAK[136.11]EPAK[136.11]K[136.11].S "sp|Q86U44|MTA70_HUMAN,tr|F5H6D8|F5H6D8_HUMAN,tr|H0YFV6|H0YFV6_HUMAN,tr|B4DTN4|B4DTN4_HUMAN" 4 3301.674 0.01 148610 22461 3 3301.667068 1101.5653 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 4.87 3822.6 - 555683 - - - -2.098 - 3.688 0.692 - 334.9 1 2 1 -0.0069 33 0 0 0 7.66E+06 6.50E+08 - - - 9.2557 0.9504 221125_WJC_METTL3_EV_vs_WT_F10.22465.22465.2 5.78 18-Mar K.FLLFGIQDGK.R "sp|P22105|TENX_HUMAN,tr|A0A140TA52|A0A140TA52_HUMAN,tr|A0A140T956|A0A140T956_HUMAN,tr|A0A140TA33|A0A140TA33_HUMAN,tr|A0A140T8Y3|A0A140T8Y3_HUMAN,tr|A0A3B3ISX9|A0A3B3ISX9_HUMAN,tr|A0A140T9C0|A0A140T9C0_HUMAN,tr|A0A140T902|A0A140T902_HUMAN,tr|A0A140T8Z8|A0A140T8Z8_HUMAN,tr|A0A140TA41|A0A140TA41_HUMAN" 10 1136.623 875.68 148612 22465 2 1136.623072 569.3188 Tenascin-X OS=Homo sapiens OX=9606 GN=TNXB PE=1 SV=5 5.84 3823.2 - 27388.4 - - - 0.0669 - 0.927 0.129 - 23.2 3 2 0 0.0001 10 0 0 0 5.11E+06 5.83E+03 - - - -0.4309 1 221125_WJC_METTL3_EV_vs_WT_F10.22485.22485.3 3.74E-10 21/128 R.R[166.11]AEQDSTTVAAFASSLVSGLNSSASEPAK[136.11]EPAK[136.11].K "sp|Q86U44|MTA70_HUMAN,tr|F5H6D8|F5H6D8_HUMAN,tr|H0YFV6|H0YFV6_HUMAN,tr|B4DTN4|B4DTN4_HUMAN" 4 3331.6742 0.01 148616 22485 3 3332.667461 1111.5653 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 4.87 3826.7 - 14726.4 - - - 298.1228 - 4.369 0.684 - 351.3 1 2 1 0.9932 33 0 0 0 2.39E+05 2.79E+07 - - - 9.2832 1 221125_WJC_METTL3_EV_vs_WT_F10.22491.22491.4 2.14E-13 32/192 R.R[166.11]AEQDSTTVAAFASSLVSGLNSSASEPAK[136.11]EPAK[136.11].K "sp|Q86U44|MTA70_HUMAN,tr|F5H6D8|F5H6D8_HUMAN,tr|H0YFV6|H0YFV6_HUMAN,tr|B4DTN4|B4DTN4_HUMAN" 4 3331.6742 29.81 148618 22491 4 3332.669978 833.9258 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 4.87 3827.5 - 498912 - - - 298.8783 - 5.188 0.691 - 632.9 1 2 1 0.9958 33 0 0 0 7.62E+09 2.56E+08 - - - 5.4586 0.9987 221125_WJC_METTL3_EV_vs_WT_F10.22507.22507.4 0.00774 5/114 K.R[166.11]GLLQDDAHPTLVTYADHSK[136.11].L "sp|Q86U44|MTA70_HUMAN,tr|F5H6D8|F5H6D8_HUMAN,tr|H0YFV6|H0YFV6_HUMAN,tr|B4DTN4|B4DTN4_HUMAN" 4 2254.1461 0.001 148626 22507 4 2254.14278 564.5438 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 5.99 3829.7 - 64263.2 - - - -1.4795 - 1.461 0.36 - 10.2 5 2 0 -0.0033 20 0 0 0 0.00E+00 1.04E+07 - - - 1.9525 0.9978 221125_WJC_METTL3_EV_vs_WT_F10.22512.22512.2 0.0418 26-Apr K.LVINGNPITIFQER.D sp|P04406|G3P_HUMAN 1 1612.8937 1.48 148628 22512 2 1612.894622 807.4541 Glyceraldehyde-3-phosphate dehydrogenase OS=Homo sapiens OX=9606 GN=GAPDH PE=1 SV=3 6 3830.6 - 45258.1 - - - 0.5772 - 0.995 0.376 - 36.1 1 2 0 0.0009 14 0 0 0 8.95E+05 6.06E+05 - - - 1.8053 1 221125_WJC_METTL3_EV_vs_WT_F10.22608.22608.4 3.58E-09 14/198 R.SDSPVPTAPTSGGPK[136.11]PSTASAVPELATDPELEK[136.11]K[136.11].L "sp|Q86U44|MTA70_HUMAN,tr|B4E349|B4E349_HUMAN,tr|F5H6D8|F5H6D8_HUMAN,tr|B4DTN4|B4DTN4_HUMAN" 4 3384.7363 0.001 148656 22608 4 3384.739616 847.1913 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 4.51 3846.2 - 125501 - - - 0.9912 - 2.996 0.576 - 66.6 1 2 0 0.0034 34 0 0 0 0.00E+00 8.74E+06 - - - 4.5658 0.9999 221125_WJC_METTL3_EV_vs_WT_F10.22690.22690.4 0.00313 9/114 K.R[166.11]GLLQDDAHPTLVTYADHSK[136.11].L "sp|Q86U44|MTA70_HUMAN,tr|F5H6D8|F5H6D8_HUMAN,tr|H0YFV6|H0YFV6_HUMAN,tr|B4DTN4|B4DTN4_HUMAN" 4 2254.1461 0.001 148672 22690 4 2254.148303 564.5438 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 5.99 3860.2 - 69237.3 - - - 0.9707 - 1.394 0.429 - 37.1 1 2 0 0.0022 20 0 0 0 0.00E+00 5.40E+06 - - - 3.0705 0.9972 221125_WJC_METTL3_EV_vs_WT_F10.22692.22692.2 0.061 18-Apr K.LLEPVLLLGK.E "sp|P62249|RS16_HUMAN,tr|M0R210|M0R210_HUMAN,tr|M0R3H0|M0R3H0_HUMAN,tr|M0QX76|M0QX76_HUMAN,tr|M0R1M5|M0R1M5_HUMAN,tr|Q6IPX4|Q6IPX4_HUMAN" 6 1093.7111 0.94 148673 22692 2 1093.711931 547.8628 40S ribosomal protein S16 OS=Homo sapiens OX=9606 GN=RPS16 PE=1 SV=2 6 3860.6 - 32853.4 - - - 0.7753 - 1.053 0.338 - 44.6 1 2 0 0.0008 10 0 0 0 3.86E+06 4.12E+06 - - - 1.6814 0.996 221125_WJC_METTL3_EV_vs_WT_F10.22702.22702.2 0.0664 18-Jun K.LLEPVLLLGK[136.11].E "sp|P62249|RS16_HUMAN,tr|M0R210|M0R210_HUMAN,tr|M0R3H0|M0R3H0_HUMAN,tr|M0QX76|M0QX76_HUMAN,tr|M0R1M5|M0R1M5_HUMAN,tr|Q6IPX4|Q6IPX4_HUMAN" 6 1101.7253 0.94 148676 22702 2 1101.727136 551.8699 40S ribosomal protein S16 OS=Homo sapiens OX=9606 GN=RPS16 PE=1 SV=2 6 3862.1 - 53223.6 - - - 1.6819 - 1.213 0.294 - 100.7 1 2 0 0.0019 10 0 0 0 3.86E+06 4.12E+06 - - - 1.7509 1 221125_WJC_METTL3_EV_vs_WT_F10.22749.22749.3 5.78E-07 Jul-68 K.STSESFIQHIVSLVHHVK[136.11].E "sp|Q9NYF8|BCLF1_HUMAN,tr|E9PKI6|E9PKI6_HUMAN,tr|A0A1W2PQ43|A0A1W2PQ43_HUMAN,tr|E9PK91|E9PK91_HUMAN,tr|E9PJA7|E9PJA7_HUMAN,tr|E9PK09|E9PK09_HUMAN,tr|E9PQN2|E9PQN2_HUMAN" 7 2055.0993 2.75 148686 22749 3 2055.101991 686.0404 Bcl-2-associated transcription factor 1 OS=Homo sapiens OX=9606 GN=BCLAF1 PE=1 SV=2 6.78 3870 - 50991.7 - - - 1.3221 - 1.706 0.616 - 55 1 2 0 0.0027 18 0 0 0 3.01E+06 1.09E+06 - - - 6.7371 0.9976 221125_WJC_METTL3_EV_vs_WT_F10.22788.22788.4 4.66E-12 18/192 R.R[166.11]AEQDSTTVAAFASSLVSGLNSSASEPAK[136.11]EPAK[136.11].K "sp|Q86U44|MTA70_HUMAN,tr|F5H6D8|F5H6D8_HUMAN,tr|H0YFV6|H0YFV6_HUMAN,tr|B4DTN4|B4DTN4_HUMAN" 4 3331.6742 0.001 148696 22788 4 3332.67096 833.9258 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 4.87 3876 - 324488 - - - 299.173 - 3.845 0.653 - 145 1 2 1 0.9967 33 0 0 0 0.00E+00 6.95E+06 - - - 5.0377 0.9982 221125_WJC_METTL3_EV_vs_WT_F10.22795.22795.3 0.00426 Aug-76 K.R[166.11]GLLQDDAHPTLVTYADHSK[136.11].L "sp|Q86U44|MTA70_HUMAN,tr|F5H6D8|F5H6D8_HUMAN,tr|H0YFV6|H0YFV6_HUMAN,tr|B4DTN4|B4DTN4_HUMAN" 4 2254.1461 0.001 148699 22795 3 2254.14648 752.3893 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 5.99 3876.9 - 77036.6 - - - 0.1619 - 1.466 0.309 - 65.4 1 2 0 0.0004 20 0 0 0 0.00E+00 7.20E+05 - - - 2.913 0.9999 221125_WJC_METTL3_EV_vs_WT_F10.22799.22799.4 8.66E-05 10/198 R.SDSPVPTAPTSGGPK[136.11]PSTASAVPELATDPELEK[136.11]K[136.11].L "sp|Q86U44|MTA70_HUMAN,tr|B4E349|B4E349_HUMAN,tr|F5H6D8|F5H6D8_HUMAN,tr|B4DTN4|B4DTN4_HUMAN" 4 3384.7363 0 148700 22799 4 3384.736526 847.1913 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 4.51 3877.6 - 106233 - - - 0.0783 - 2.196 0.441 - 36.4 1 2 0 0.0003 34 0 0 0 1.31E+04 8.30E+06 - - - 3.299 0.9998 221125_WJC_METTL3_EV_vs_WT_F10.22870.22870.4 0.00025 14/84 R.STSHK[136.11]PDEIYGMIER[166.11].L sp|Q86U44|MTA70_HUMAN 1 1779.8581 0.001 148720 22870 4 1779.852337 445.9718 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 5.42 3888.8 - 484325 - - - -3.2121 - 2.384 0.478 - 152.4 1 2 0 -0.0057 15 0 0 0 0.00E+00 3.91E+06 - - - 3.6958 1 221125_WJC_METTL3_EV_vs_WT_F10.22881.22881.4 6.48E-06 17/114 K.R[166.11]GLLQDDAHPTLVTYADHSK[136.11].L "sp|Q86U44|MTA70_HUMAN,tr|F5H6D8|F5H6D8_HUMAN,tr|H0YFV6|H0YFV6_HUMAN,tr|B4DTN4|B4DTN4_HUMAN" 4 2254.1461 0 148723 22881 4 2254.145906 564.5438 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 5.99 3890.6 - 227272 - - - -0.0927 - 3.215 0.573 - 286.3 1 2 0 -0.0002 20 0 0 0 4.56E+04 2.40E+07 - - - 4.6038 1 221125_WJC_METTL3_EV_vs_WT_F10.22997.22997.4 1.90E-08 12/198 R.SDSPVPTAPTSGGPK[136.11]PSTASAVPELATDPELEK[136.11]K[136.11].L "sp|Q86U44|MTA70_HUMAN,tr|B4E349|B4E349_HUMAN,tr|F5H6D8|F5H6D8_HUMAN,tr|B4DTN4|B4DTN4_HUMAN" 4 3384.7363 0.01 148746 22997 4 3384.73419 847.1913 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 4.51 3909.9 - 159831 - - - -0.6119 - 2.417 0.57 - 62.2 1 2 0 -0.0021 34 0 0 0 2.24E+05 1.51E+07 - - - 4.4499 0.9632 221125_WJC_METTL3_EV_vs_WT_F10.23005.23005.4 0.00112 5/168 R.R[166.11]AEQDSTTVAAFASSLVSGLNSSASEPAK[136.11].E "sp|Q86U44|MTA70_HUMAN,tr|F5H6D8|F5H6D8_HUMAN,tr|H0YFV6|H0YFV6_HUMAN,tr|B4DTN4|B4DTN4_HUMAN" 4 2898.4326 0.001 148752 23005 4 2899.426516 725.6154 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 4.68 3911.1 - 77176.7 - - - 342.9219 - 1.209 0.408 - 5.7 1 2 0 0.9939 29 0 0 0 0.00E+00 5.93E+05 - - - 2.5604 0.9999 221125_WJC_METTL3_EV_vs_WT_F10.23071.23071.4 3.42E-07 17/114 K.R[166.11]GLLQDDAHPTLVTYADHSK[136.11].L "sp|Q86U44|MTA70_HUMAN,tr|F5H6D8|F5H6D8_HUMAN,tr|H0YFV6|H0YFV6_HUMAN,tr|B4DTN4|B4DTN4_HUMAN" 4 2254.1461 -1 148775 23071 4 2254.1409 564.5438 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 5.99 3920.9 - 278084 - - - -2.3135 - 3.309 0.503 - 278.3 1 2 0 -0.0052 20 0 0 0 0.00E+00 0.00E+00 - - - 4.0027 1 221125_WJC_METTL3_EV_vs_WT_F10.23085.23085.3 3.48E-12 24/124 R.AEQDSTTVAAFASSLVSGLNSSASEPAK[136.11]EPAK[136.11].K "sp|Q86U44|MTA70_HUMAN,tr|F5H6D8|F5H6D8_HUMAN,tr|H0YFV6|H0YFV6_HUMAN,tr|B4DTN4|B4DTN4_HUMAN" 4 3165.5648 0 148780 23085 3 3166.553698 1056.1956 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 4.41 3923 - 434930 - - - 312.3822 - 4.565 0.644 - 476.2 1 2 1 0.9889 32 0 0 0 2.62E+04 9.07E+06 - - - 8.9394 1 221125_WJC_METTL3_EV_vs_WT_F10.23089.23089.4 1.18E-11 11/186 R.AEQDSTTVAAFASSLVSGLNSSASEPAK[136.11]EPAK[136.11].K "sp|Q86U44|MTA70_HUMAN,tr|F5H6D8|F5H6D8_HUMAN,tr|H0YFV6|H0YFV6_HUMAN,tr|B4DTN4|B4DTN4_HUMAN" 4 3165.5648 0.001 148782 23089 4 3166.555374 792.3985 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 4.41 3923.6 - 178495 - - - 312.9116 - 3.084 0.669 - 53.9 1 2 1 0.9905 32 0 0 0 0.00E+00 5.80E+06 - - - 5.1146 0.9678 221125_WJC_METTL3_EV_vs_WT_F10.23110.23110.3 0.0575 May-56 R.STSHK[136.11]PDEIYGMIER[166.11].L sp|Q86U44|MTA70_HUMAN 1 1779.8581 0.001 148790 23110 3 1779.848363 594.2933 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 5.42 3926.8 - 70052 - - - -5.4448 - 1.134 0.373 - 33.2 1 2 0 -0.0097 15 0 0 0 0.00E+00 5.33E+06 - - - 3.024 0.9974 221125_WJC_METTL3_EV_vs_WT_F10.23128.23128.3 8.83E-06 7/128 R.R[166.11]AEQDSTTVAAFASSLVSGLNSSASEPAK[136.11]EPAK[136.11].K "sp|Q86U44|MTA70_HUMAN,tr|F5H6D8|F5H6D8_HUMAN,tr|H0YFV6|H0YFV6_HUMAN,tr|B4DTN4|B4DTN4_HUMAN" 4 3331.6742 1.51 148796 23128 3 3331.661219 1111.5653 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 4.87 3929.3 - 31623.5 - - - -3.9001 - 2.004 0.476 - 44.3 1 2 1 -0.013 33 0 0 0 8.37E+05 5.54E+05 - - - 5.4426 0.9847 221125_WJC_METTL3_EV_vs_WT_F10.23132.23132.2 0.0123 22-May K.VDLLNQEIEFLK.V sp|P35908|K22E_HUMAN 1 1459.7922 999 148797 23132 2 1459.786977 730.9034 "Keratin, type II cytoskeletal 2 epidermal OS=Homo sapiens OX=9606 GN=KRT2 PE=1 SV=2" 4.14 3929.8 - 48633.4 - - - -3.6094 - 0.993 0.364 - 54.4 1 2 0 -0.0053 12 0 0 0 1.16E+06 0.00E+00 - - - 1.7094 1 221125_WJC_METTL3_EV_vs_WT_F10.23220.23220.4 1.56E-09 21/102 R.SPSELFAQHIVTIVHHVK.E "sp|Q9Y2W1|TR150_HUMAN,tr|A0A3B3ITZ9|A0A3B3ITZ9_HUMAN" 2 2041.1109 3.34 148821 23220 4 2041.115591 511.285 Thyroid hormone receptor-associated protein 3 OS=Homo sapiens OX=9606 GN=THRAP3 PE=1 SV=2 6.78 3943.1 - 200111 - - - 2.3007 - 3.488 0.601 - 328.8 1 2 0 0.0047 18 0 0 0 4.34E+06 1.30E+06 - - - 4.8838 1 221125_WJC_METTL3_EV_vs_WT_F10.23223.23223.4 1.45E-10 20/102 R.SPSELFAQHIVTIVHHVK[136.11].E "sp|Q9Y2W1|TR150_HUMAN,tr|A0A3B3ITZ9|A0A3B3ITZ9_HUMAN" 2 2049.1251 3.34 148822 23223 4 2049.126531 513.2886 Thyroid hormone receptor-associated protein 3 OS=Homo sapiens OX=9606 GN=THRAP3 PE=1 SV=2 6.78 3943.5 - 198515 - - - 0.7008 - 3.316 0.552 - 334.8 1 2 0 0.0014 18 0 0 0 4.34E+06 1.30E+06 - - - 4.4409 0.9981 221125_WJC_METTL3_EV_vs_WT_F10.23224.23224.4 0.0119 8/108 R.GLLQDDAHPTLVTYADHSK[136.11].L "sp|Q86U44|MTA70_HUMAN,tr|F5H6D8|F5H6D8_HUMAN,tr|H0YFV6|H0YFV6_HUMAN,tr|B4DTN4|B4DTN4_HUMAN" 4 2088.0367 0.001 148823 23224 4 2088.035803 523.0165 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 5.13 3943.6 - 127365 - - - -0.4454 - 1.511 0.278 - 17.3 1 2 0 -0.0009 19 0 0 0 0.00E+00 1.38E+06 - - - 1.7851 1 221125_WJC_METTL3_EV_vs_WT_F10.23227.23227.4 999 2/144 R.K[136.11]GGDSDYDDDDDDDSDDQGDEDDED.E sp|Q9UIF8|BAZ2B_HUMAN 1 2773.8594 0.001 148824 23227 4 2773.878839 694.4721 Bromodomain adjacent to zinc finger domain protein 2B OS=Homo sapiens OX=9606 GN=BAZ2B PE=1 SV=3 3.2 3944 - 239953 - - - 7.0029 - 0.172 0.833 - 1.1 1 1 0 0.0194 25 0 0 0 0.00E+00 1.58E+06 - - - 5.9111 1 221125_WJC_METTL3_EV_vs_WT_F10.23229.23229.4 2.69E-10 17/222 K.GILGYTEHQVVSSDFNSDTHSSTFDAGAGIALNDHFVK.L "sp|P04406|G3P_HUMAN,tr|E7EUT5|E7EUT5_HUMAN" 2 4035.8875 0.92 148825 23229 4 4035.887541 1009.9792 Glyceraldehyde-3-phosphate dehydrogenase OS=Homo sapiens OX=9606 GN=GAPDH PE=1 SV=3 4.7 3944.3 - 249389 - - - 0.0092 - 3.654 0.586 - 90.7 1 2 0 0 38 0 0 0 2.48E+06 2.69E+06 - - - 4.7044 0.9899 221125_WJC_METTL3_EV_vs_WT_F10.23246.23246.4 9.60E-08 18/204 K.QSKPVTTPEEIAQVATISANGDKEIGNIISDAMK[136.11]K[136.11].V "sp|P10809|CH60_HUMAN,tr|A0A7I2V599|A0A7I2V599_HUMAN,tr|E7EXB4|E7EXB4_HUMAN,tr|A0A7I2YQ71|A0A7I2YQ71_HUMAN,tr|E7ESH4|E7ESH4_HUMAN,tr|A0A7I2V5M1|A0A7I2V5M1_HUMAN,tr|A0A7I2V5K3|A0A7I2V5K3_HUMAN,tr|A0A7I2V369|A0A7I2V369_HUMAN" 8 3698.9372 - 148836 23246 4 3698.900701 925.7416 "60 kDa heat shock protein, mitochondrial OS=Homo sapiens OX=9606 GN=HSPD1 PE=1 SV=2" 4.94 3946.5 - 566694 - - - -9.8555 - 3.805 0.525 - 89.6 1 2 1 -0.0365 35 0 0 0 - - - - - 4.1817 0.9996 221125_WJC_METTL3_EV_vs_WT_F10.23261.23261.4 5.14E-06 21/150 R.SFGTEDRPTDRPIPPRDEVFEYIIFR.G "sp|Q8ND56|LS14A_HUMAN,tr|I3L4Q1|I3L4Q1_HUMAN,tr|A0A140TA76|A0A140TA76_HUMAN,tr|K7EMZ9|K7EMZ9_HUMAN" 4 3151.5727 1.06 148841 23261 4 3151.561822 788.9005 Protein LSM14 homolog A OS=Homo sapiens OX=9606 GN=LSM14A PE=1 SV=3 4.59 3948.6 - 490403 - - - -3.4513 - 2.208 0.549 - 70.6 1 2 1 -0.0109 26 0 0 0 1.30E+07 1.22E+07 - - - 4.2513 0.9949 221125_WJC_METTL3_EV_vs_WT_F10.23265.23265.3 0.00281 May-60 K.K[136.11]VSQEILELLNTTTAK[136.11].E "sp|Q86U44|MTA70_HUMAN,tr|H0YFV6|H0YFV6_HUMAN" 2 1803.0324 0.01 148843 23265 3 1803.024107 602.0181 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 6.14 3949.1 - 73806.8 - - - -4.6161 - 1.256 0.434 - 28.2 1 2 0 -0.0083 16 0 0 0 2.84E+04 2.78E+06 - - - 3.9612 0.9998 221125_WJC_METTL3_EV_vs_WT_F10.23281.23281.4 4.06E-07 22/114 K.R[166.11]GLLQDDAHPTLVTYADHSK[136.11].L "sp|Q86U44|MTA70_HUMAN,tr|F5H6D8|F5H6D8_HUMAN,tr|H0YFV6|H0YFV6_HUMAN,tr|B4DTN4|B4DTN4_HUMAN" 4 2254.1461 0 148849 23281 4 2254.135548 564.5438 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 5.99 3951.5 - 556489 - - - -4.6878 - 3.627 0.55 - 421.6 1 2 0 -0.0106 20 0 0 0 9.16E+04 3.35E+07 - - - 4.441 0.9984 221125_WJC_METTL3_EV_vs_WT_F10.23293.23293.4 1.01E-09 28/174 K.R[166.11]R[166.11]AEQDSTTVAAFASSLVSGLNSSASEPAK[136.11].E "sp|Q86U44|MTA70_HUMAN,tr|F5H6D8|F5H6D8_HUMAN,tr|H0YFV6|H0YFV6_HUMAN,tr|B4DTN4|B4DTN4_HUMAN" 4 3064.542 0.01 148854 23293 4 3064.523678 767.1428 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 6.18 3953 - 914468 - - - -5.966 - 4.04 0.583 - 459.1 1 2 1 -0.0183 30 0 0 0 1.57E+05 1.28E+07 - - - 4.7226 1 221125_WJC_METTL3_EV_vs_WT_F10.23309.23309.4 4.25E-07 10/102 K.STSESFIQHIVSLVHHVK[136.11].E "sp|Q9NYF8|BCLF1_HUMAN,tr|E9PKI6|E9PKI6_HUMAN,tr|A0A1W2PQ43|A0A1W2PQ43_HUMAN,tr|E9PK91|E9PK91_HUMAN,tr|E9PJA7|E9PJA7_HUMAN,tr|E9PK09|E9PK09_HUMAN,tr|E9PQN2|E9PQN2_HUMAN" 7 2055.0993 2.5 148857 23309 4 2055.094988 514.7821 Bcl-2-associated transcription factor 1 OS=Homo sapiens OX=9606 GN=BCLAF1 PE=1 SV=2 6.78 3955.5 - 129097 - - - -2.0855 - 2.43 0.558 - 78.4 1 2 0 -0.0043 18 0 0 0 4.08E+06 1.64E+06 - - - 4.3858 0.9999 221125_WJC_METTL3_EV_vs_WT_F10.23313.23313.4 4.97E-07 16/102 K.STSESFIQHIVSLVHHVK.E "sp|Q9NYF8|BCLF1_HUMAN,tr|E9PKI6|E9PKI6_HUMAN,tr|A0A1W2PQ43|A0A1W2PQ43_HUMAN,tr|E9PK91|E9PK91_HUMAN,tr|E9PJA7|E9PJA7_HUMAN,tr|E9PK09|E9PK09_HUMAN,tr|E9PQN2|E9PQN2_HUMAN" 7 2047.0851 2.5 148859 23313 4 2047.07796 512.7785 Bcl-2-associated transcription factor 1 OS=Homo sapiens OX=9606 GN=BCLAF1 PE=1 SV=2 6.78 3956 - 310892 - - - -3.4752 - 3.053 0.585 - 129.2 1 2 0 -0.0071 18 0 0 0 4.08E+06 1.64E+06 - - - 4.6982 0.9973 221125_WJC_METTL3_EV_vs_WT_F10.23330.23330.4 4.41E-06 14/168 R.KDGNASGTTLLEALDC[160.03]ILPPTRPTDKPLR.L "sp|P68104|EF1A1_HUMAN,sp|Q5VTE0|EF1A3_HUMAN,tr|A0A7I2V659|A0A7I2V659_HUMAN,tr|A0A7I2V3H3|A0A7I2V3H3_HUMAN,tr|A0A7I2V5N4|A0A7I2V5N4_HUMAN,tr|A0A087WVQ9|A0A087WVQ9_HUMAN,tr|A0A087WV01|A0A087WV01_HUMAN" 7 3148.655 0.22 148866 23330 4 3148.633037 788.171 Elongation factor 1-alpha 1 OS=Homo sapiens OX=9606 GN=EEF1A1 PE=1 SV=1 6.16 3958.3 - 216464 - - - -6.9906 - 2.813 0.468 - 67.5 1 2 0 -0.022 29 0 0 0 1.26E+06 5.76E+06 - - - 3.6121 0.9679 221125_WJC_METTL3_EV_vs_WT_F10.23334.23334.3 0.0581 May-60 R.THNLEPYFESFINNLR.R sp|P04264|K2C1_HUMAN 1 1992.9694 15.85 148868 23334 3 1992.965007 665.3304 "Keratin, type II cytoskeletal 1 OS=Homo sapiens OX=9606 GN=KRT1 PE=1 SV=6" 5.37 3958.7 - 38725.9 - - - -2.1922 - 1.127 0.241 - 25.5 1 2 0 -0.0044 16 0 0 0 3.55E+06 2.24E+05 - - - 1.5325 0.9719 221125_WJC_METTL3_EV_vs_WT_F10.23338.23338.3 0.478 Apr-64 R.THNLEPYFESFINNLRR.R sp|P04264|K2C1_HUMAN 1 2149.0705 999 148869 23338 3 2149.069012 717.3641 "Keratin, type II cytoskeletal 1 OS=Homo sapiens OX=9606 GN=KRT1 PE=1 SV=6" 6.42 3959.3 - 47488.2 - - - -0.6863 - 0.903 0.261 - 19.3 1 2 0 -0.0015 17 0 0 0 7.90E+05 0.00E+00 - - - 1.1917 1 221125_WJC_METTL3_EV_vs_WT_F10.23342.23342.4 6.76E-14 21/192 R.AEQDSTTVAAFASSLVSGLNSSASEPAK[136.11]EPAK[136.11]K[136.11].S "sp|Q86U44|MTA70_HUMAN,tr|F5H6D8|F5H6D8_HUMAN,tr|H0YFV6|H0YFV6_HUMAN,tr|B4DTN4|B4DTN4_HUMAN" 4 3301.674 0.03 148871 23342 4 3301.657035 826.4258 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 4.87 3959.8 - 303535 - - - -5.1368 - 3.83 0.718 - 205.4 1 2 1 -0.017 33 0 0 0 3.74E+06 1.22E+08 - - - 5.8737 0.8845 221125_WJC_METTL3_EV_vs_WT_F10.23368.23368.3 3.53 Apr-76 K.R[166.11]GLLQDDAHPTLVTYADHSK[136.11].L "sp|Q86U44|MTA70_HUMAN,tr|F5H6D8|F5H6D8_HUMAN,tr|H0YFV6|H0YFV6_HUMAN,tr|B4DTN4|B4DTN4_HUMAN" 4 2254.1461 0.03 148884 23368 3 2254.13848 752.3893 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 5.99 3963.4 - 35158.9 - - - -3.3871 - 0.84 0.281 - 10.6 1 2 0 -0.0076 20 0 0 0 1.97E+04 6.61E+05 - - - 1.2478 0.9997 221125_WJC_METTL3_EV_vs_WT_F10.23374.23374.2 0.0452 22-Jul R.NLDLDSIIAEVK.A "sp|P48668|K2C6C_HUMAN,sp|P04259|K2C6B_HUMAN,sp|P13647|K2C5_HUMAN,sp|P35908|K22E_HUMAN,sp|O95678|K2C75_HUMAN,sp|Q5XKE5|K2C79_HUMAN,sp|P02538|K2C6A_HUMAN,tr|H0YI76|H0YI76_HUMAN,tr|H0YIN9|H0YIN9_HUMAN" 9 1328.7187 218.02 148888 23374 2 1328.717519 665.3666 "Keratin, type II cytoskeletal 6C OS=Homo sapiens OX=9606 GN=KRT6C PE=1 SV=3" 4.03 3964.2 - 72454.1 - - - -0.9242 - 1.944 0.395 - 95.9 1 2 0 -0.0012 12 0 0 0 2.03E+06 9.30E+03 - - - 3.7071 0.9996 221125_WJC_METTL3_EV_vs_WT_F10.23385.23385.2 0.0271 22-Aug R.SLDLDSIIAEVK.A sp|P04264|K2C1_HUMAN 1 1301.7078 999 148893 23385 2 1301.705251 651.8612 "Keratin, type II cytoskeletal 1 OS=Homo sapiens OX=9606 GN=KRT1 PE=1 SV=6" 4.03 3965.8 - 76952.2 - - - -1.9951 - 1.922 0.444 - 134.2 1 2 0 -0.0026 12 0 0 0 2.00E+06 0.00E+00 - - - 4.0387 0.9999 221125_WJC_METTL3_EV_vs_WT_F10.23446.23446.4 1.31E-07 9/192 R.R[166.11]AEQDSTTVAAFASSLVSGLNSSASEPAK[136.11]EPAK[136.11].K "sp|Q86U44|MTA70_HUMAN,tr|F5H6D8|F5H6D8_HUMAN,tr|H0YFV6|H0YFV6_HUMAN,tr|B4DTN4|B4DTN4_HUMAN" 4 3331.6742 0.11 148914 23446 4 3331.665644 833.9258 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 4.87 3975.2 - 84653.5 - - - -2.572 - 2.509 0.624 - 33.4 1 2 1 -0.0086 33 0 0 0 4.06E+05 3.80E+06 - - - 4.9309 0.994 221125_WJC_METTL3_EV_vs_WT_F10.23449.23449.2 0.00563 Apr-34 R.GDADQASNILASFGLSAR.D "sp|P43243|MATR3_HUMAN,tr|A8MXP9|A8MXP9_HUMAN,tr|D6R991|D6R991_HUMAN,tr|A0A0R4J2E8|A0A0R4J2E8_HUMAN,tr|D6REM6|D6REM6_HUMAN" 5 1791.8751 2.02 148916 23449 2 1791.868282 896.9448 Matrin-3 OS=Homo sapiens OX=9606 GN=MATR3 PE=1 SV=2 4.21 3975.6 - 19234.4 - - - -3.8278 - 1.058 0.47 - 34.5 1 2 0 -0.0069 18 0 0 0 1.45E+05 7.20E+04 - - - 2.6489 0.9999 221125_WJC_METTL3_EV_vs_WT_F10.23495.23495.4 7.57E-05 15/114 K.R[166.11]GLLQDDAHPTLVTYADHSK[136.11].L "sp|Q86U44|MTA70_HUMAN,tr|F5H6D8|F5H6D8_HUMAN,tr|H0YFV6|H0YFV6_HUMAN,tr|B4DTN4|B4DTN4_HUMAN" 4 2254.1461 0.001 148946 23495 4 2254.141513 564.5438 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 5.99 3982.1 - 102610 - - - -2.0416 - 2.541 0.456 - 182.9 1 2 0 -0.0046 20 0 0 0 0.00E+00 4.60E+06 - - - 3.5055 1 221125_WJC_METTL3_EV_vs_WT_F10.23499.23499.3 1.85E-12 13/84 R.K[136.11]PLVIIAEDVDGEALSTLVLNR[166.11].L "sp|P10809|CH60_HUMAN,tr|A0A7I2V2X6|A0A7I2V2X6_HUMAN,tr|A0A7I2YQK6|A0A7I2YQK6_HUMAN,tr|A0A7I2V599|A0A7I2V599_HUMAN,tr|A0A7I2YQ71|A0A7I2YQ71_HUMAN,tr|A0A7I2V5M1|A0A7I2V5M1_HUMAN,tr|A0A7I2V5K3|A0A7I2V5K3_HUMAN" 7 2382.3489 1.44 148949 23499 3 2382.344491 795.1236 "60 kDa heat shock protein, mitochondrial OS=Homo sapiens OX=9606 GN=HSPD1 PE=1 SV=2" 4.32 3982.6 - 91843.4 - - - -1.8494 - 2.936 0.68 - 140.1 1 2 0 -0.0044 22 0 0 0 2.49E+06 1.73E+06 - - - 8.6736 1 221125_WJC_METTL3_EV_vs_WT_F10.23535.23535.4 7.30E-07 13/198 R.SDSPVPTAPTSGGPK[136.11]PSTASAVPELATDPELEK[136.11]K[136.11].L "sp|Q86U44|MTA70_HUMAN,tr|B4E349|B4E349_HUMAN,tr|F5H6D8|F5H6D8_HUMAN,tr|B4DTN4|B4DTN4_HUMAN" 4 3384.7363 0.001 148964 23535 4 3384.734969 847.1913 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 4.51 3987.9 - 204817 - - - -0.3817 - 2.696 0.595 - 66.2 1 2 0 -0.0013 34 0 0 0 0.00E+00 1.46E+07 - - - 4.7003 0.9999 221125_WJC_METTL3_EV_vs_WT_F10.23568.23568.4 7.46E-09 10/192 R.AEQDSTTVAAFASSLVSGLNSSASEPAK[136.11]EPAK[136.11]K[136.11].S "sp|Q86U44|MTA70_HUMAN,tr|F5H6D8|F5H6D8_HUMAN,tr|H0YFV6|H0YFV6_HUMAN,tr|B4DTN4|B4DTN4_HUMAN" 4 3301.674 0.01 148972 23568 4 3301.670614 826.4258 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 4.87 3993.2 - 88026.5 - - - -1.024 - 2.271 0.636 - 38.3 1 2 1 -0.0034 33 0 0 0 4.92E+04 6.01E+06 - - - 5.0069 1 221125_WJC_METTL3_EV_vs_WT_F10.23569.23569.4 6.49E-05 7/162 K.DGNASGTTLLEALDC[160.03]ILPPTR[166.11]PTDK[136.11]PLR[166.11].L "sp|P68104|EF1A1_HUMAN,sp|Q5VTE0|EF1A3_HUMAN,tr|A0A7I2V659|A0A7I2V659_HUMAN,tr|A0A7I2V3H3|A0A7I2V3H3_HUMAN,tr|A0A7I2V5N4|A0A7I2V5N4_HUMAN,tr|A0A087WVQ9|A0A087WVQ9_HUMAN,tr|A0A087WV01|A0A087WV01_HUMAN" 7 3048.5908 0.22 148973 23569 4 3048.584828 763.155 Elongation factor 1-alpha 1 OS=Homo sapiens OX=9606 GN=EEF1A1 PE=1 SV=1 4.68 3993.3 - 32451.9 - - - -1.9671 - 1.47 0.582 - 20.5 1 2 0 -0.006 28 0 0 0 6.39E+04 2.86E+05 - - - 4.4097 0.9471 221125_WJC_METTL3_EV_vs_WT_F10.23664.23664.3 1.69E-08 20/100 H.NVQPNWITLGNQLDGIHLLDPDVVAR[166.11].F sp|Q86U44|MTA70_HUMAN 1 2906.5278 -1 149017 23664 3 2907.527382 969.8499 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 4.41 4007.2 - 205334 - - - 343.9055 - 3.437 0.567 - 204.1 1 1 0 0.9996 26 0 0 0 0.00E+00 0.00E+00 - - - 7.425 1 221125_WJC_METTL3_EV_vs_WT_F10.24434.24434.3 0.000197 Sep-52 K.K[136.11]GPGEVAGTVTGQK[136.11].R "sp|Q86U44|MTA70_HUMAN,tr|F5H6D8|F5H6D8_HUMAN,tr|H0YFV6|H0YFV6_HUMAN,tr|B4DTN4|B4DTN4_HUMAN" 4 1343.738 0.001 149121 24434 3 1343.738367 448.9199 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 8.59 4136.5 - 232287 - - - 0.2887 - 2.367 0.488 - 134.3 1 2 0 0.0004 14 0 0 0 0.00E+00 1.29E+06 - - - 6.2704 0.9995 221125_WJC_METTL3_EV_vs_WT_F10.24435.24435.2 0.00245 26-Jun K.K[136.11]GPGEVAGTVTGQK[136.11].R "sp|Q86U44|MTA70_HUMAN,tr|F5H6D8|F5H6D8_HUMAN,tr|H0YFV6|H0YFV6_HUMAN,tr|B4DTN4|B4DTN4_HUMAN" 4 1343.738 -1 149122 24435 2 1343.737067 672.8763 N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2 8.59 4136.6 - 28920.6 - - - -0.6787 - 1.427 0.432 - 89.4 1 2 0 -0.0009 14 0 0 0 0.00E+00 0.00E+00 - - - 3.1238